LOCUS       DAOQPD010000001       164295 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_24_length_164295_cov_19.783415, whole genome shotgun sequence.
ACCESSION   DAOQPD010000001 DAOQPD010000000
VERSION     DAOQPD010000001.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 164295)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 164295)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..164295
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_24_length_164295_cov_19.783415"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            314..1174
                     /locus_tag="PK063_00005"
     CDS             314..1174
                     /locus_tag="PK063_00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HMZ95441.1"
                     /translation="MKSKSIGILTKPKFPEVKATVQAVVSWLRSRNIDVLLDTTSTTL
                     LGEQGGFQKTQLASKADVLLVLGGDGTMLNAARLAGERGIPILGVNMGGLGFLTEVVL
                     ENLYPSLERVFANDFVLDERLMLRTHVHRHGETVARGVVLNDVVISKGTLARMIELKI
                     AIQGQFVTNLRGDGLIISTPTGSTAYSLSAGGPIINPAVPSLILTPICPHTLTHRPLI
                     VPASAQIEVVLTSKDDGAMATLDGQVGVALSQGDTVEIHASEHLTRLIRFPESSYYEV
                     LREKLKWGDG"
     gene            complement(1190..2560)
                     /locus_tag="PK063_00010"
     CDS             complement(1190..2560)
                     /locus_tag="PK063_00010"
                     /inference="COORDINATES: protein motif:HMM:NF019604.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HMZ95442.1"
                     /translation="MSATGSETSGHVVVVVGAGPAGMALAKKMADAGHEVIILNRDIK
                     FGGLAEYGIFPSKLKLRGGLKKQYWDMLEQPNVHYFGNVSVGQGKDLTVEELRGLGAS
                     AVAFSIGAQGTKAIGVEGDSAKGVFHAKDVVYHFNRLPGFGDRPFDMGKHVAIIGVGD
                     VMVDIAHWLIRYKKVERVTAIARRGPVERKYNPKEIRAVCSNMDHEGIAQEFARIKDR
                     LAAVGQNADEVLANLTAEFTKCEPTGSSSKMGFRFLASPKRVLVDANNRVRALEMEEN
                     KLEPKGEDTAAVGLKQLYEFPVDSVVFAVGDRVDETVGLPYKNGVYVTNPTKTANDPD
                     DSLFQAYDEKSGQVVDGVFLAGWARKASEGLVGIAKRDGDWCAEVISRYLTTKSVQSV
                     SGVDQVLSKLQAILKERKSKPVDLEGLKVLDTVEKAHAASPEAIGEFKFASNADMLAH
                     IERGRA"
     gene            complement(2745..4202)
                     /locus_tag="PK063_00015"
     CDS             complement(2745..4202)
                     /locus_tag="PK063_00015"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004333 - fumarate hydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0006106 - fumarate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006108 - malate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fumarate hydratase"
                     /protein_id="HMZ95443.1"
                     /translation="MMKNASRTPKSTASATTATRMERDTMGELPVPSNAYYGVQTARA
                     IENFPISSLRIPRAMIRAMGLIKRAAASVNHSLKLLDKKPADAIIRAATEVVDGGLDA
                     EFPVDIFQTGSGTSTNMNTNEVISNRATELLGGARGSKLVHPNDHVNLGQSSNDVIPT
                     AIHIAASETIQRQLLPALTQLHKALSGKAREFDKIVKIGRTHLQDATPVRLGQEFGGY
                     ARQIELGIARMKRAQAALSEVALGGTAVGTGLNCHPKFAGKVMALISKETGCSFKEAV
                     NHFEGQSAQDSLVEASGELRTLAVSLMKIANDIRWLGSGPRCGLGEINLPETQPGSSI
                     MPGKVNPVIAESVTMVCAQVIGNDVTITVGGQAANFELIVMLPVMAYNLLQSIELLST
                     ASTNFAVKCIAGIKANEERCKSLIEESLAMCTALAPVIGYEAAAKLAKDAYKSGKTVR
                     EVAREQNVLPEKRLNQLLDPWRMTQAGGPVGSAGG"
     gene            complement(4409..4864)
                     /locus_tag="PK063_00020"
     CDS             complement(4409..4864)
                     /locus_tag="PK063_00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HMZ95444.1"
                     /translation="MAIVRWDPFRELEEMSDRLNRMITRPGAAQTATQGKEVMTVADW
                     APTVDISETEAEYAIKAELPEVKKEDVKVTVEDGVLTLQGERKQEKEDKGKKYHRIER
                     SYGRFVRSFTLPDTVDESKVKAEYTDGVLHLHLPKSEKAKPKQIDVKIA"
     gene            complement(5154..6287)
                     /locus_tag="PK063_00025"
     CDS             complement(5154..6287)
                     /locus_tag="PK063_00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate synthase"
                     /protein_id="HMZ95445.1"
                     /translation="MPHDFMPGLAGVPAAKSAISDVDGIRGVLEYRGIRVEELCQHSS
                     FLETSYLLLFGRLPTATELTQWVDDVTHHRRIKFRIVDLLKVMPEHGHPMDALQAAVA
                     ALGMFYPGRNVKDVENNYWSAVRLIAKLPTIVAAWARLRRGDEYIPPRDDLPFADNFL
                     YMLTETVPHPLWSAVFDDCLILHAEHTMNASTFAGMVTASTLADPYTVVASSIGALKG
                     PLHGGANEEVVTMLKEIGTPAQARAAVEARLGGKNKLMGFGHRVYKVKDPRATVLQDL
                     CMRLFNVCGTSPLYEVAVAVEQLASERLQGKGIYPNVDFYSGIIYDKMGIEVDLFTPL
                     FAMARVSGWLAHWLEQLRENKLYRPDQIYSGEHDRHYVPIDRR"
     gene            6758..7141
                     /locus_tag="PK063_00030"
     CDS             6758..7141
                     /locus_tag="PK063_00030"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95446.1"
                     /translation="MGRFRSLALGVLMVIGLNVPAWADDEQVFFAVVSDVPKDKTRIS
                     AKVLQDGASSDIKLIPSESVVANPVWRTLEVCHALKIEGMKIGDGLKVMSARVLDASM
                     LPMGLQGFAGDCLIKKAVEIAPLAE"
     gene            complement(7199..7573)
                     /locus_tag="PK063_00035"
     CDS             complement(7199..7573)
                     /locus_tag="PK063_00035"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95447.1"
                     /translation="MPIFGTDTSDQTGKFSCATATQRTLKDLRTKRKGQPVFVVGHRL
                     ERKGKEATFEVFNDRLAIIRFEDDVRLGYDPFELLLPTEIDDKGVAYFEIRTCRLCEQ
                     FFPLTADECDEEEERTTCPECA"
     gene            7674..8024
                     /gene="arsC"
                     /locus_tag="PK063_00040"
     CDS             7674..8024
                     /gene="arsC"
                     /locus_tag="PK063_00040"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248978.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0008794 - arsenate reductase
                     (glutaredoxin) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HMZ95448.1"
                     /translation="MAEITIYQKPTCSTCREAVRLVRESGQPFTAVNYYEQPFTKSRL
                     KELLKKAGLSPRDVLRTKEDLYKSLKLADSTLSDDHLLDQMIAHPDLIQRPIVVKGDK
                     VMLARPADTVTELL"
     gene            8085..8327
                     /locus_tag="PK063_00045"
     CDS             8085..8327
                     /locus_tag="PK063_00045"
                     /inference="COORDINATES: protein motif:HMM:NF040329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95449.1"
                     /translation="MLAFDSVDRVSLLGRVLQRLNLRFPSLFVLFAVLTLVDVIVPDV
                     IPLADEIGFALLTLLLGMWKDRRHQPRQRTAGKAFR"
     gene            complement(8361..9566)
                     /gene="rnd"
                     /locus_tag="PK063_00050"
     CDS             complement(8361..9566)
                     /gene="rnd"
                     /locus_tag="PK063_00050"
                     /EC_number="3.1.13.5"
                     /inference="COORDINATES: protein motif:HMM:TIGR01388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - endoribonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease D"
                     /protein_id="HMZ95450.1"
                     /translation="MATLDPDQTFITSDHMLDRLCDQLANSAVIAIDTEFMGEDHFIP
                     RLELIQVAAEGVAAVIDFPAVQDSAPMVRFWELVCDARIEKVLHAGRQDLELFAHHAG
                     RLPKPFFDTQIAAAMVGYGAQTAYANLVQRVQGVKLDKAHTFTNWSQRPLSKDQLVYA
                     LDDVTFLLPIHRHLRQKLSVMGRLDWVDEEFSRLEVSLGAQARDPQERYQRIRGWDSL
                     KPRAAGVLRDLAAWREGEARRRNVPRGRVMRDEVLVQLARQTPRTLDQLRGMRGMYSS
                     EVERNGQALLATMQQALARPESEWPEVPRDRKPDPESTGVLELLQAVLKSRAAMENIA
                     PTLIATTGDLQALVERTSPVEEVDIPVLRGWRRQLVGETLLSVLSGNLKVWIDPQIGK
                     LRFGHLDHP"
     gene            complement(9570..10199)
                     /locus_tag="PK063_00055"
     CDS             complement(9570..10199)
                     /locus_tag="PK063_00055"
                     /inference="COORDINATES: protein motif:HMM:NF012451.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="HMZ95451.1"
                     /translation="MAFSTNRLFKYQRGMRRRIGMLRAKNIDSMEFAVDFMMQERVDS
                     YFRIEPALEEVERSLGQIEDELDLVKDVSGAIRLESRLEFVEDRWDELDSEIRERPRR
                     RRRKINLADFLKAAGGEGNPAGTSSEVTNAYDAYQLLGLEFGTPLADVTTAFRQRAKE
                     LHPDARNGDRSSEPELRRILEAYQFLKEYLSLSNTEPPISRGAEYRPTE"
     gene            complement(10311..11570)
                     /locus_tag="PK063_00060"
     CDS             complement(10311..11570)
                     /locus_tag="PK063_00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative Na+/H+ antiporter"
                     /protein_id="HMZ95452.1"
                     /translation="MTPTTIQLIGTLLFAVAILHTFATAFFEHLAHTRPAHAGLWHLL
                     GEVEVAFGFWALVLIVAMFVTDGAAAATHYLDSRSFTEPLFVFAIMVIAGTRPILQTA
                     MTGVRIVSSAIPLPQGMRVYLTVLALVPLLGSFITEPAAMTLAALLLRDVFFRHGCST
                     NLKYATLGVLFVNVSIGGTLTPFAAPPVLMVAGAWQWDIAFMLGTFGWKAALAVLINA
                     FGATMLFRRELSRISTAIDQREENRAPLALVITHLALLAMVVVFAHHPAMFLGILLLF
                     LGIAQAYEQYQDRLILREGLLVSFFLAGLVVLGGQQQWWLQPILLGMGADAVFVGATI
                     LTAFTDNAALTYLGSLVEGLSDAFKYALVAGAVTGGGLTIIANAPNPAGLAILRTYFD
                     DEAVHPLRLFLAALPPTLIAAAMFWCL"
     gene            complement(11738..13180)
                     /locus_tag="PK063_00065"
     CDS             complement(11738..13180)
                     /locus_tag="PK063_00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HMZ95453.1"
                     /translation="MTTDDIGPYSNYRLTVRLALLNKPGIFAKVAALLAEEGANLGAV
                     DIVSANAERMIRDITFDVQNEAHGDRVLERLEALPEVNVLSASDRIFLLHLGGKIRVQ
                     SKVPVTTRNVLSMIYTPGVGRVCKAIAKDPVKAYAFTSKSNSVAVVTDGSAVLGLGNL
                     GPAAALPVMEGKVMLFRELAGIDAWPICVSTQDPEEIIRIVRGIAPGFGGINLEDISA
                     PRCFEIERALKTSLDIPVMHDDQHGTAVVLLAALTNALKVVGKRMEDVRIVVNGLGAA
                     GTACCRILLAAGACHLVGCDKEGIVLMGEAEELRACRTDLQACIRRDQPRGTIHDALR
                     GADVFIGLSVGNVLEKADLDNMNSDRIVFAMANPDPEIDPKIGDEVSRIFATGRSDYP
                     NQINNALSFPGIFRGALDVQASEINEAMKLAAAQAIAECVPTEALSEDYIIPSVFDRD
                     VVPRVAKAVAAAARTTGVARRRIKIEDDPR"
     gene            13572..13796
                     /locus_tag="PK063_00070"
     CDS             13572..13796
                     /locus_tag="PK063_00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95454.1"
                     /translation="MKRALFAFVAAAILVAFTAPSFAGDDKKKEEKKGGHFSQTLFGD
                     DKKKEEKKGGHLSQTVFGEEKKKDEKKGGH"
     gene            13946..17635
                     /locus_tag="PK063_00075"
     CDS             13946..17635
                     /locus_tag="PK063_00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HMZ95455.1"
                     /translation="MTDHHANRPANRLIRETSPYLLQHAYNPVDWYPWGPEALAQAAA
                     LKRPILLSIGYSSCHWCHVMERESFENEAIAALMNQHFICVKVDREERPDLDEIYMQA
                     TLALNRNQGGWPMTVFLTPDQKPFFAGTYFPPTDRYGRPGFPTLLKKIAEYWEKDHDG
                     VVAQAVNLTARLQEGAHAPSPTTVGEAELDMAVTQFAEDFDARQGGFGGAPKFPPATG
                     LSLLLHCYQRTKDPHTLTMVRKTLDAMAAGGIYDHIGGGFARYSTDERWLVPHFEKML
                     YDNALLARVYVEAYQVTADETYRRVACETLDYILKEMTSPEGGFYSATDADSEGVEGK
                     FFVWTPEDVRAAVDSDEEARRFCAYYDVTAGGNWEHTNVLHTAKSVEAVAKELSITAG
                     ELTETITRLRPKLYAVRAKRIAPGLDDKVITAWNGMMISAMAEAGRVFDIPRYREAAE
                     RACDFLLTTLSTADGRLLRTYRAGTAHLNAYLEDYAYFAEGLIDTYEAGGEERYLLAS
                     VRLAERMLADFADSQHGGFFTTATGHEALIMRSREGPDGATPSGNAVAASVLARLSSH
                     FAREDFREAATAAVRAYGRQIARYPRAFAKSLIVVDFLMSGPAEIALVGRLGDQGMES
                     LRAAVNRTYLPNRVLVHRDSDQSATSHPLLQGKTLIDGKAAVYVCRNFACGRPITDPK
                     EFPSLLDPRQQASSPPASEQKILSGTLYPGHATVQGTAAYAARHIHESNGALAHGFAL
                     FGATGLTASRLGFGTYRVGQREAEHREALRSALRQGCNVIDTSTNYMDGESEQLVGSV
                     LREMMRAGDLTREGVIVVSKIGYVQGQNLTQAQAREKSGKPYPDMVKYGDDIWHCIHP
                     EFLADQLTLSLDRLGLATLDVCLLHNPEYFLSHATRLGGDESRDLPALRQEFYARLQR
                     AFEYFETQVQAGRLRGYGVSSNTATSAPDDPGATSLSHMIDAAKLAATTVGAPSHHFQ
                     VLQCPMNVYESGAALIKNTGIHNGSTLLEEAMRERIAVLVNRPLNAMPVQRGGVIRLA
                     DVSVPAPEADFEAQRKKVAALEEEYRNSLAPAVAHSGQGMLPADFFRWADELTRIRGQ
                     VQGLEHWEQIEQQMIAPHVNQVLRALAEAFTGNVAEQWESWRDRYVPELLALLRILHR
                     EASEKSRLRSDELHHTMNPLLPEQRRTATLSQKALWVLASTPGVTCVLNGMRTPAYVE
                     DALTILQWPPLPEWRSVYDRCAGKK"
     gene            17710..18285
                     /locus_tag="PK063_00080"
     CDS             17710..18285
                     /locus_tag="PK063_00080"
                     /inference="COORDINATES: protein motif:HMM:NF012894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HMZ95456.1"
                     /translation="MIVLRPFALVGLLAVAAPFLFDGCASKAGTSGGATVTPSKPRVE
                     ERIAAAPVQEIPPAPEPAPVPLRSVEMAARNATGEQNIPFPDVLFDFDQYVLRDDALN
                     AVEANAKRLKDNRVTKVLLEGRCDEIGTAEYNLVLGERRALSVKRYLESLGMSQVQVD
                     VTSYGKDRPLCLQHNPVCWQKNRSVHFVVKE"
     gene            18492..18875
                     /locus_tag="PK063_00085"
     CDS             18492..18875
                     /locus_tag="PK063_00085"
                     /inference="COORDINATES: protein motif:HMM:NF012780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HMZ95457.1"
                     /translation="MVTVSELMTKKLVTVPVGTTTAEAAKVMNERHVGSVFIEQNNRV
                     VGIVTESDIVRKVVGENKPVHFVPVESIMSSPVISLDERRSITEAADLMQCHHTRHLG
                     VLQSGAIVGVLSVRDLLQPVAVDEF"
     gene            19380..20498
                     /locus_tag="PK063_00090"
     CDS             19380..20498
                     /locus_tag="PK063_00090"
                     /inference="COORDINATES: protein motif:HMM:NF024921.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PstS family phosphate ABC transporter
                     substrate-binding protein"
                     /protein_id="HMZ95458.1"
                     /translation="MLSHGQKHGWRRRAVVVGLAGILATAESLAVLPAGVARAENAGP
                     TASLAIQEGLVQYNPQTQVAGSLRVQGSDTMSLLMSRLAGEFQRRQPNVSINVSGGGS
                     TKAVNEFVQPPAKLSGKITLKEERPTYVSLVASSRELLDAEVKQFVAQHGYEPTAIPV
                     AVDAVALYVHRDNPIQGLTLDQVDAMFSTTHNRGLKTSLSQWGALGLQDGWEKAPVRL
                     YGRDRRSGTRAFFQEHCLAGGEFAPSVREEPGAASVILDLTRDQLGIGYSGLGLETSN
                     VRIVPLAENQGMPFIAPTATTVSDQTYPLRRMLYLYVDKSPKAALAPAVQEFLTFVTS
                     REGQEAVMKAGFFPLPMNQLKKNFLALGLSGQETPLPN"
     gene            complement(21012..21986)
                     /locus_tag="PK063_00095"
     CDS             complement(21012..21986)
                     /locus_tag="PK063_00095"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95459.1"
                     /translation="MPVASMVTIPYPRLALRRSLCLVLLMYLTSACSLLTGGKVLFDQ
                     QDSQVGVQTDPTVHRGPAPTENNHPAQLTTEEVRVLLGSLMVSGWSGTLVGILERPRP
                     IPVFTELELNRIAAPVAAAFQQATPSERVFFSLPKSQTTYSEERTTGALFLRGRYLHV
                     VLTDHSAFTRADTAGGEVKDLRDTKGMKLWVTAPATAATVPDAEEPRWAHFETVHVSL
                     NAKEVIAARNRPASPSADVSPSISLHPSEAVGAGAKSNGPADTTGNQTDELRLQVREL
                     TTSNLELRNRLDTQLKQMQALQDQLTKLQQDLDSARAKSKTPRRSTTP"
     gene            complement(22321..22860)
                     /locus_tag="PK063_00100"
     CDS             complement(22321..22860)
                     /locus_tag="PK063_00100"
                     /inference="COORDINATES: protein motif:HMM:NF015782.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Slp family lipoprotein"
                     /protein_id="HMZ95460.1"
                     /translation="MKIYRGAIAAVLIGLVLNGCGPQRVFSPQVLDGVDPNFDFTAWR
                     MVPNAKAGKKVQLGGRILQAPQKDGLVTMVLTQLPIVEHPAYGPTDTERGRGEFLVYF
                     NGKVPTNHLQPGNRVIAIGTTQNAAVVAIEDSQRSLPALTAQCLHIWNTGGKEIADFP
                     NFGAGYQPLEEETYCAESR"
     gene            complement(22929..24467)
                     /locus_tag="PK063_00105"
     CDS             complement(22929..24467)
                     /locus_tag="PK063_00105"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95461.1"
                     /translation="MEMRPLVASISGLVGSAMLGLCVTASWADDSSRQGQSSHTVVAQ
                     AMGPAPNGTSSPPPAPDMPLGGTSIEDLLMQKGTITKEEWIQIRAEQEYKAGERDKRV
                     DSLDEWKSKAELLPILRDKVNFGLNALQWLYTHQDAHVPEGRSQDNLSIRRSEILFWG
                     RISDTLPRWHTLMEFQSINLLNNTPTGGSAATGGVPTSSTFFREAYLDIRPVQSWAPN
                     VNYFRMGIFRMPFGIFTETSGGLRDVISSPYLTSVGSGVGNRTGSAGTVEFLQERDYF
                     LDMRGKLFNRLEYVVGIMNNNNYEANATGSNAPKSFYSRVRLFGSDVSFISFTTIQGE
                     SNNANTNINGRGKGAFDRYGLDFRYTSKILPGFMVQGEIWQGHDGANQTTVGRPANGA
                     CDVQAICGGSGAPGVQRRTWYVLAKYLITDGPFENFEPVIMYEQFDPNTRIGNDLYTR
                     TIVGLSYYFENFPPKVQSKLQVNYEFRHHSGNGPNNVVDPTRGVGDPFAQNAFLVQWQ
                     IRFM"
     gene            complement(24622..25332)
                     /locus_tag="PK063_00110"
     CDS             complement(24622..25332)
                     /locus_tag="PK063_00110"
                     /inference="COORDINATES: protein motif:HMM:NF012698.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ95462.1"
                     /translation="MQHATEPLRHHGIPVLLVTKDEEFAMSVHQLLRPNGYHVSLAPT
                     AEAALSLASGASFKLALIDRRHKVVGTLRQNLAFRHIPMIALQPLGEPCTEEETVEDL
                     AAGFDIVIDSHRHREWLAIIKALLRRQEIQAAPLREFRVNTLCMNLDRHEVRVEGKSI
                     QLTPKEFQILRVLLQHPGRVLTRQELLNLVWGEDYALEEHALDVHIHALRHKLETKPS
                     APQWILTVRGVGYKLSTD"
     gene            25504..26103
                     /locus_tag="PK063_00115"
     CDS             25504..26103
                     /locus_tag="PK063_00115"
                     /inference="COORDINATES: protein motif:HMM:NF017913.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-starvation-inducible PsiE family
                     protein"
                     /protein_id="HMZ95463.1"
                     /translation="MKVMVHGDPGTDLSSTLLNHDRVIHQEVSQMTFTSFPVRVPRVA
                     DLAGRAIETDLTDLWMKGIKAVLSLLILTILIALTGGVIKTFLDIKLLLEAPVEVGLR
                     QIIVDTLILLAVVEVFKTTLTYFSEGRVKVTFIVDTILVVMLTEIISLWFKEADQTKL
                     LSLGAIVLALGAVRVVAVRCSPAQGDGNGKCAGSCREGI"
     gene            26168..26503
                     /locus_tag="PK063_00120"
     CDS             26168..26503
                     /locus_tag="PK063_00120"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95464.1"
                     /translation="MLHSQLHVIQQSAGCQGQRVEGLGTFQPGGSTMVHQSAVLSSEC
                     RVLELLHGRKSLTLEQVVTLLPELSWNQVFKTIDELSRHGKIILLRRGFDYEIERISS
                     RQPALSCFG"
     gene            complement(26540..27232)
                     /locus_tag="PK063_00125"
     CDS             complement(26540..27232)
                     /locus_tag="PK063_00125"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ95465.1"
                     /translation="MRPSTVHIVEDEPLHAGLLDRALRLAGFDTLLSSDGASGWQEIQ
                     RRLPTLILLDLMLPALSGQEICRMVRQHSATRHIPIIMLTAVGGEPERIAGLDMGADD
                     YVVKPFSPREVVSRVRTVLRRGAHSADGVAPIVNAAVRMQGPYFAVLLGERELLLSRK
                     ETALLQTLLGRENALVAAEELLTLPEGERPGLLLQELDYDVRGLRRKLENSGAGSVDM
                     LPGFRYRFRSRL"
     gene            27447..28457
                     /locus_tag="PK063_00130"
     CDS             27447..28457
                     /locus_tag="PK063_00130"
                     /inference="COORDINATES: protein motif:HMM:TIGR02136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HMZ95466.1"
                     /translation="MTVSRQICLSLTLTALGPFMTMCLVSAAPGDTPAVETLTVDAGI
                     KPYHKVSGVSGTINSIGSDTLNNLITLWAEGFRKQYPNVKIQVEGKGSSTAPPALIEN
                     TAQLGPMSRTMKSSEIDAFESKFGYPPTAYPVAVDALALFVNKDNPVAGLTIAEVDAL
                     FSKSRRQGHTTDLTRWGQLGQNGDWANAPVSLYGRNSASGTYGFFKDHALKNGDFKDQ
                     VKEQPGSASVVQGISEDRYGIGYSGIGYSTSGVKMVPLAAKAGQPYIEPTQANTKNGT
                     YPLWRYLYIYVNQAPGKPLSPIVKEFLAYVYSKEGQSDVLRDGYFPVDAKLAEQQLGK
                     IR"
     gene            28457..30685
                     /locus_tag="PK063_00135"
     CDS             28457..30685
                     /locus_tag="PK063_00135"
                     /inference="COORDINATES: protein motif:HMM:NF012738.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HMZ95467.1"
                     /translation="MITNPLSYLSGPVHLRSVIDRLARGIITVGGLATIVSILGIFFF
                     LFREVTPLFTAPSAKLSQRLSVPALLADEGPAQVAVDEHREIAQVFTSGAIQFFDLAS
                     GQPIALEMPAQLTSRQVTAMASGGGPTARLAVGTAAGEILLLKIGTTTEFSDQGERRK
                     RPHVRAGAPIPVTDSPIVRLAYRSNDHGSLLALATKTGRLFLARIAPDDPTGAGVMVT
                     ELPQPSGGVASLALEASLDHLYVGTTDGHIIHVGVSETQPPDVRASYAVAGPTTAISM
                     LGFLSGDRSLVVMAADGAVSTWGLVRRSDVPTGWTLTQMHTFRSHAAPVTAFAPSQRV
                     KGFVTGDTKGNVFLHHATSSQTLLRVANGEFPIRAVAFAPKGDGVIALDGAGQLSLYQ
                     VQNPYPEVTLDTLFGKVWYEGYGQPAYVWQSSSGSDEVEPKLGLLPLAFGTLKGTIYA
                     LFLAVPIAIFAAICTSQFMHHDLRAKVKPIIEVMAALPTVVLGFLAGLWLAPLLERML
                     PALAGMVLVLPVLVIVASFSWHLCPMSIKRHFSPGNEALLLMPILALGIGGCLWAHSF
                     FEVWWFDGNIKTWLSSRLGIQYDQRNALVVGIVMGFAIVPVIYSIAEEALSNVPKSQI
                     AGSLALGATRWQTVLHLVLLSASPGIFSGVMIGFGRAIGETMIVLMATGNTPILDWNW
                     ANGFRTLSANIAVEIPEAPHGGSLYRVLFLAALLLFIVTFVINSLAELVRQRLRDKYS
                     HG"
     gene            30678..32327
                     /gene="pstA"
                     /locus_tag="PK063_00140"
     CDS             30678..32327
                     /gene="pstA"
                     /locus_tag="PK063_00140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HMZ95468.1"
                     /translation="MGKPSLRMKEFWRGGELFVWMTASGVAISLLMVAGMLVLIMFNG
                     LGQFWPGTLQQVTLKTQETVIGHLVGEETIPHSMTTDALLGQRRFRYRVGNRDQFGSE
                     YRWINESEIASISAPDDLVFVERREWGPAYGRISLAAESTAATNADGSAWSTIETLVD
                     RANQLRQRIEHLEREDIGSINYRIEKARLARQTLVLKGAHNPASIEADRRLVEQIAAL
                     EREYLSKTDALEQLHKEATQEVVLLTLSTGRSVRLSLDQVLAVSRPNAMNGFEKAVAY
                     VRNLWHFVSGEPREANTEGGIFPAIFGTVLMVFLMTLAVMPFGVMAAVYLREYAKQGP
                     LVRLVRIAVNNLAGVPSIVFGVFGLAFFVYALGGTIDQILFPESLPNPTFGTGGILWA
                     SLTLALLTVPVVIVATEEGLSAVPRDFREGSVGLGATKFETIRHVILPCALPGILTGL
                     ILAMARAAGEVAPLMLTGVVKLAPALPLDEYLPFLHLERKFMHLGFHIYDVGFQSPNV
                     EAAKPMVYMTTLILILVVVLLNLAAVMLRNRLRKRFATSAV"
     gene            32454..33209
                     /gene="pstB"
                     /locus_tag="PK063_00145"
     CDS             32454..33209
                     /gene="pstB"
                     /locus_tag="PK063_00145"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004810563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HMZ95469.1"
                     /translation="MQTKISVRDLDFYYGHRQALFHVGLTIRSHSVTAFIGPSGCGKS
                     TLLRCLNRMNDLVEGARPVGRVELDGMDIYDPAIDVTDLRKRVGMVFQKSNPFPKSIY
                     DNVAYGPRLHGIKDKRSLDERVQHSLQGAGLWDEVKDRLQHSAVGLSGGQQQRLCIAR
                     ALAVQPEVILMDEPCSALDPIATGKIEELIYSLKETYTVVIVTHNMQQAARVSDQCGF
                     FLMGELVEFGDTKTIFTTPRDKRTEDYITGRFG"
     gene            33231..33899
                     /gene="phoU"
                     /locus_tag="PK063_00150"
     CDS             33231..33899
                     /gene="phoU"
                     /locus_tag="PK063_00150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0051049 - regulation of transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HMZ95470.1"
                     /translation="MQRHFDQDLAHLKQQLLRMGGLVESQIQQALQALVDRDSDLAVD
                     VIKQDHDVNGLDVEIDELCVQLLALQQPTARDLRFVTTGMKISSELERMGDLADNIAQ
                     RALELNSEPQLKPYIDIPRMANWTMRMVKECLDAFVNSDPVLARKVCTDDDFVDEVNE
                     QLFRELLSFMLEDTRTITRAIRLTFVAKSLERIADHATNIAELVVYMVEGKNIRHVAP
                     TASF"
     gene            33900..35453
                     /locus_tag="PK063_00155"
     CDS             33900..35453
                     /locus_tag="PK063_00155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA phosphatase family protein"
                     /protein_id="HMZ95471.1"
                     /translation="MPKLAVLDIGTNSIHMVLAEVQPDYSYKILDRFKDMTRLGDGVF
                     TSRRLSDQAMMRGLEVIRTLVNLARNKGYEQIEGVATSAVREARNGGEFLDHVMQQTG
                     LTVRVITGAEEARLIFLGVQNSVALPESPTLVIDIGGGSVEVIVGNREAIFQARSLKL
                     GAIRLKDLYLSKTPPSKAMLRDLEAAVTAQLKNALGSYKTKRVEQIIATSGMAGNLAE
                     VIHLQRTGRPLPQLNLARVSAKDIAAVEKRLAGASLKTRLAMPGLDPKRVDTLLPAAI
                     VFRILLELLQKTELTLCDKAIREGIIYDFIQRHHDRIQAERDIPDVRKRNILALAHRC
                     HVSETHALHVAGLALRLFDQTKALHGLGQREREWLEGAAILHDIGYMINSRQHHKHAY
                     YLIKNSDLSGFTAEEIDLIANIARYHRRSVPTRKHDEFTVLPEGSQRVINVLSALLRI
                     ADGLDRSQFSVVQNIDVKLGKTVVITAQVSGDAELEIWAARGRSDLFEKVFKRPVQFI
                     TTTRDDDAT"
     gene            complement(35579..36076)
                     /locus_tag="PK063_00160"
     CDS             complement(35579..36076)
                     /locus_tag="PK063_00160"
                     /inference="COORDINATES: protein motif:HMM:NF012521.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HMZ95472.1"
                     /translation="MDCLLFRHGIAYDREDWRGNEHNRPLTDKGLVRTRQSSKGLLTL
                     GCIPTLILSSPLTRAQQTAKIARSLIPATPPLRICQELNPEVPPRALIALLNTLPSDA
                     VVLCVGHEPHLSATAGILLTGKLCKGLSLKKAGACLLHLEGSVRPAKGRLEWWLTASQ
                     LRALA"
     gene            36180..37034
                     /locus_tag="PK063_00165"
     CDS             36180..37034
                     /locus_tag="PK063_00165"
                     /inference="COORDINATES: protein motif:HMM:NF017085.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAD domain-containing protein"
                     /protein_id="HMZ95473.1"
                     /translation="MGDMLHSIHTGPQSPTQGLLTMAASSHATVLHLLRQAIAGREHV
                     DTIHAIRTHCRRLQALLELYGEAKRARAVAACVRRLSKLRALQVFRQYVIRCHAGRKD
                     VAVVDDRLTKQIRKLNHTEAYRRIEQVVSKQALPAILSPPQSWNRRLDELRQEHECAL
                     KRLIAAASDKPRRKRLHALRLALKTIRYQTEWLPGRTAAKEEMLSQLKRVQSLLGKYE
                     ELADFHRWGKKLSLPVRKRMKKDWKRARKRARHVPGTMSWLLDALASGHVWSGENLHV
                     ASVNRRSA"
     gene            complement(37011..37733)
                     /locus_tag="PK063_00170"
     CDS             complement(37011..37733)
                     /locus_tag="PK063_00170"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ95474.1"
                     /translation="MALEIIEIVEDDQSQAKLLDQILRQASYRTNVAFDGPAGMQDVW
                     RIKPSLIVADDNLPGLTGREMCKRLRQDPSTTHIPIIVMSGFSSEERRAEALDAGADD
                     FIVKPYSGMELLARVRALLRRCRQSQAQDEELPEDLALTENLYVAVYRGKSLTLSAHE
                     WKALRRLASTVGNVVPREELKSLLWGDDSLMHDGELDRCMQQLNRKLSQDAPLVESIK
                     IVPGGFRLSTPASDDSGGPAVH"
     gene            complement(37823..39247)
                     /locus_tag="PK063_00175"
     CDS             complement(37823..39247)
                     /locus_tag="PK063_00175"
                     /inference="COORDINATES: protein motif:HMM:NF024793.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HMZ95475.1"
                     /translation="MYERFYHLTVKPFTLVPNPDFLYRGETHRLALTTLEYGILNHAG
                     FVVLTGEPGMGKTTLIQQILAEHRNHFTTGLITNTHEGMETLLPWILLAFGQNDKNLD
                     KLEGFHAFQQFLGKEAAAKRRVLLIVDEAQNLGANLLEELRLLSNLNKDKAPILQIIL
                     SGQPDLRQLLQRKDLTQFAQRVMVDYSLEPFKEEDSIGYIAHRLRVAGREEPLFTHEA
                     ARTIHRLTGGIPRLINQLCDTALTYGFAEEAPFLSARIVAQAAKDRTKGGILPLSNTE
                     SLTAVTPDQQAAEQTELAALSARAASTSNEVPRRDDAVPTSSGVATARPDTNEQYERG
                     LSLKKAGSYKEALQAFSLAAQDAAFTFKAMAQVGICLKSLAQPEEAVTAFRKSLQAKR
                     SASPDTIQVRYLLARTLESLERTDDALEQYRWIGREEPSFKDVAERLERLHGRPIRST
                     RNEAASSDGSSWVTQLQRILGASK"
     gene            complement(39274..40110)
                     /locus_tag="PK063_00180"
     CDS             complement(39274..40110)
                     /locus_tag="PK063_00180"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0004715 - non-membrane spanning protein
                     tyrosine kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HMZ95476.1"
                     /translation="MEPLHSAMERFKREEQRRPTPVVLKAPPPRIGKDAVQDIVYTHT
                     RTVDIPDDVLRERRVLAGFERGPFLDAYKILRTQVMHRLREHGWNVLGITSPSKQEGK
                     TLTAVNLAISLAMDTTQTVLLVDADLTNPSAHLAFGIEECGGLVDYLLDGIPVEHLLI
                     HPGIGRFVLMPAGRSITNSTEALTSPKMASLVEEFKHRYPSRIVLFDLPPLLQTADVL
                     AFSPYTDALLLVVEDGKTTREEVERALQLVKGSTPVLGTVLNKAGKGHMTPAAMKRML
                     LT"
     gene            complement(40129..41874)
                     /locus_tag="PK063_00185"
     CDS             complement(40129..41874)
                     /locus_tag="PK063_00185"
                     /inference="COORDINATES: protein motif:HMM:NF014732.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="HMZ95477.1"
                     /translation="MNKPTVGIQDIISMAKRRKMPIIMITLGILLLGATLAFTIPAVY
                     RSTATILIEEQEIPSDLVRSAITTYADQRIETIKQQVMSRSTLWKIVEQYDLYKHMRK
                     QSPTEEVLHRFTKDTNIDVINAKVVDKRTQNPTQATIAFTLSYDGESPESAQKVANEL
                     TSLFLAENLKTRERHAQETTAFLKQEADGLSRHIEEIEKKLSIVKQRADGALPELTQL
                     NMQLLNGAERELTDTDRDIRSLEERKTFLEGELATIKPNTPILSSTGERILDSGERLK
                     ALRAEYADKAGYLSPEHPDIWKMQQEIRALERETGGAAPIDDVLKRLTGERATLATLL
                     DKYGEDHPDVTRSRRTISSLEKDLREYENAPAKMPAIKPENPAYINTQTQLASATSML
                     EALKAQRAKLRKRAEDYARRLEKTHHFEPEYLDLARERDNSARKYEELRSKLLEAQVS
                     EGLETQRKGERFSLIDPPDLPEKPEKPNRPLILLLSFVLALAGGAGSGVLLENVDRSI
                     RGPESLAHITQTYPLAVIPYIPNNADLRQLIAKRRTIRLAGIGIAAACILLAHFFWLP
                     LDVVWFAALRKFGLD"
     gene            complement(41909..43114)
                     /locus_tag="PK063_00190"
     CDS             complement(41909..43114)
                     /locus_tag="PK063_00190"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95478.1"
                     /translation="MKHRLIPTAWLWAILLTTAWSSHSLDQEVWSAEWFLEPALTVRG
                     EVNSNLTLTTFDHKTTYGHWVSPGAKFGGSTEALEVNGRLAADFVRYYGGQNTSLTNL
                     YFPLSAKYKMERDSFGFDGGFTRDNTLMGELRQTGVVLSFTQRNQWILNPSWTHAITE
                     RLSATGSYTFYDTRYENGLRLGLADYTLHVGSTGMTYQVGERDQVQLNAVGVRFNAAD
                     LRLSSTIIGPQITYSHMFSETLTGTVSGGPRHVSSTINTSAGSLSDGVWTWVFSGNLE
                     RRWEDWRVKGEIGREINPSGFGLLLRTDKLSLEVSHQMTDRLSASVTGLFLIADGVKT
                     RAVSTVFPENRLFYVTPKLSWRLSEWWTADITYTYAQRDLPSQSLTALGNSATIMFTY
                     YPPRFTVGR"
     gene            complement(43155..43772)
                     /locus_tag="PK063_00195"
     CDS             complement(43155..43772)
                     /locus_tag="PK063_00195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015159 - polysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015774 - polysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis/export family
                     protein"
                     /protein_id="HMZ95479.1"
                     /translation="MKIAGSLLIKKLARGCQPGLLALYAVVLMTGCVTPEHTAAQNMA
                     DPGYHLGPEDVVMISVWKDENLTREAIVRPDGMVSFPLIGDVPAMGHTVEEVRQDIAK
                     RLARFIPNPHVSVAITKLQSYKVYVMGRVTKPGEYLVGHYTDVLQALSLAGGLTPFAS
                     ENDIKIIRRENGDQRVFLFRYGDVQKGRDLNQNILLERGDVVMVP"
     gene            complement(43784..46189)
                     /locus_tag="PK063_00200"
     CDS             complement(43784..46189)
                     /locus_tag="PK063_00200"
                     /inference="COORDINATES: protein motif:HMM:NF024824.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ95480.1"
                     /translation="MATTWHRCHTIARFGLAIVLILAVGCGGPEERKAKYRTKAQEYL
                     QAGNFPKARVALRNVLKIDPKDSEAYFLYAQVEEKEKNWRNAFAHYQRVIELEPDHER
                     ALVKLGKFYLQGRLDEKAHETADHLLRVYPGHVSAQAIKAALLAADGKLTQAVVAGEA
                     LFKQFPTEPDAAILLSTLYALQNSPQRVEAVLRKAVAAHPHDLDLLNSLAMAYMRAGN
                     QAQAESVFRDILALEPSVFDHHLKLALFFDQQRQYDKAEAILREALRLDQDNEQRHLA
                     LADYLAGRKNVETAEAALNEAHRVLPHAVNIQFALGRLYELHQLPDKARATYEDIRDH
                     NRSKPAGGNAKIKLATLDWAAGKQDDAMQQLREVLRDNPRASDALMLEGRIALQHGSA
                     REAVQAFRTVLKDQPEQSEAYALLGQAHLMLEETSLARENLERAVTLSPNLYQAHLAL
                     AILDASSGRTRDARVRLEELLKQAPTNLGTLGMLLNLQAADRDWDGSDQTLSRIREAG
                     ANRFVADLAEGNLYQARLQWDKAVAAFERASSLNPDAPEPIFALVRIDARLGKLAQAH
                     NRLSGLIAKNAQHPFAHGLLGEILILKGDPMRAEQEFRLATTLKPEWGTPWVNWVTLK
                     LSQRKHEEAGDILQRGLQINPASEELRLLYASHLGERGQFDQAILEYETILKHNPRQL
                     MAANNLASILADQKGDAKSLDRALALSREFEQRAPNPFFLDTLGWVHLKMGHQDDAIR
                     VIQRAVTEAPQHPILNYHLGMAHFKAGHRVEAQTHLKKALNTKQPFPGMDEAKSVLAE
                     VTG"
     gene            complement(46207..47835)
                     /locus_tag="PK063_00205"
     CDS             complement(46207..47835)
                     /locus_tag="PK063_00205"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: protein motif:HMM:NF013146.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HMZ95481.1"
                     /translation="MISTLFFSFVGSLIICMALIPPLMATASRLQFLDIPKDQRRVHA
                     IPVAKVGGIAFGVGTFSAMLIWAPKDDIVVAGLLGGVTILLFGMWDDRVGLPYTIKFL
                     GQTLGALIIMWQGNIHLNSLPFVETELPLWVAYPLTTLIIVGVTNAVNLADGLDGLAG
                     GLSLLSFAGMACLAYLGGDQTVTLLMVPVLGGLLGFLRFNTYPARIFMGDAGSQFLGF
                     FMAVSAIVLTDPQRGPYTPALGLFLLGLPLLDTVGVMLQRLKEGRSPFVADKNHLHHK
                     LLAMGLSHYEAVLMIYLLQAALVTLAYILRWQSELAILSTYGLVATMILYPFLRSRSW
                     KIQSNRMLKTADRLLTRASTITSSPWLTTEPIQILGIAVPAFLILSVFLPKHVPDDMG
                     YVAAVMFAVMLIGLWASPRISSLVVRGGLYVGSTFIMYLSEQPASSTDILSPIHIFFV
                     GLAVLVALTIRFNSEHRFQTTPLDYLMVFLAIMVPALPEMQMGDIHLSFLTAKLIVLF
                     FSFELLLHVFARRLTQLALVALWLLCGIAVRAWI"
     gene            complement(47855..49474)
                     /gene="xrtD"
                     /locus_tag="PK063_00210"
     CDS             complement(47855..49474)
                     /gene="xrtD"
                     /locus_tag="PK063_00210"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: protein motif:HMM:TIGR04152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004197 - cysteine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VPLPA-CTERM-specific exosortase XrtD"
                     /protein_id="HMZ95482.1"
                     /translation="MRSTPELATKTARFLAEPVASVSAAAPTRSLALGLTVLLPVTIL
                     GLVFTDSVAYMADLWLTDENYGHGMLVPLISLYLIWQQRRRLMEQSRSGSWWGLIWIL
                     LGAALYVVGELATVYQFLHVALWCIIVGLLVSALGARAVSTIAFPLGFLLTVVPLPQF
                     LYQGLSGKLQLISSALGVGCLQFIGITAFRDGNVIDLGPIQLQVVDACSGLRYLFPLA
                     TLALLCSYLFRERLWKRIVLFISSIPISILLNGFRIGMIGVLVEHFGQGAAEGFYHAF
                     EGWVLFMASLGLLLAEMFVLRKIGATRVTRDTPSQPQPEMVPPASLPSRAILLRPTYL
                     YSVGLVCLLPFAATELTERGDVPPVRQPFLDFPMQFKGWSGTPFPLEGRYVEVLKFDD
                     YVLADYQQPQSAAVNLYIAYYRSQRKGQSAHSPQSCIPGGGWEIGTIETVQLDSAAGQ
                     APANRVSIQKGDQRQLVLYWFKQRHRIVANEYLVKLYVLWDAMTRQRTDGALIRLTTP
                     IQQNESEGAAEQRLLHFAQDMNPILTRYVPD"
     gene            complement(49471..50205)
                     /locus_tag="PK063_00215"
     CDS             complement(49471..50205)
                     /locus_tag="PK063_00215"
                     /inference="COORDINATES: protein motif:HMM:TIGR00696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HMZ95483.1"
                     /translation="MVPTRVDILNIPVDCVTMDQAVAWADSRMTLSEPKTVIAVNPEK
                     IMKAQSDPTLRQFLRSAGLLIPDGIGVVIATKLLGLGYAERVPGSELMPRLCGLAAEK
                     GYSIFLFGASPEVNERAAHKLRQEFPGLTIAGTQHGYVDDADMPAVIDHINAVAPHFL
                     FIALGSPKQELWMSTYLPRLRVKVCQGVGGTFDVLAGRVKRAPWIFRCIHLEWFYRLL
                     SQPSRLVRQTALPLFAFHILRKRVLG"
     gene            complement(50186..52129)
                     /locus_tag="PK063_00220"
     CDS             complement(50186..52129)
                     /locus_tag="PK063_00220"
                     /inference="COORDINATES: protein motif:HMM:NF019552.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HMZ95484.1"
                     /translation="MFSIDFSVNTKVLPKGLAWYAKRLSVMGPGEIMHRMREGIAMQS
                     LQLQYRLSKRATAQHYGPKDIPQHVFCSGQDQRLPSLPWKFHLAQEEIACLLNGTLSA
                     LSHEWTWRADAKVWHEAPDTRQLWPQIFFHRIPYREGNPFGDIRIAWEPSRLQHLLTL
                     ALYAQQAEPDKRRQAVAMIEGQLLSWFAANPPLTGIHYISVMECALRLMAVCHTLDLV
                     RPWLSQPEAIWAGTLNLVSTHAELIRKRVSGHSSSGNHTIAEAAGLVYAGLLFPKMEM
                     AERWLAYGLYLLEQEAPHQIRQDGGGREEAIWYLRFISDLYGLTVALLRQHEQLIPQK
                     LIQATERSHTFLQAMMRPGDGALPRIGDADSGYALSPFLQFVPVSAEAAPGLTSFHLS
                     GCSILQGSKGERLLFDHGELGMAPCYAHGHADALSVQLEIGQQEILIDPGTYSYTGHS
                     EWRRYFRSTRAHNTVTVDGRDQATQETSFLWSQPFETHLIYRDETPEGKITVLARHYG
                     YTQPCGVTHWRGVVYQPPGAWLIWDWLTGTGTHHLELNWHLGVSPVQNSASYVLACRE
                     QPVQISVEGGLASLHHGETAPPSGWRSSTYGSKEPITTLRAEYRGALPHEFLTRIWCG
                     EGPPPTQLQTFSLSRSFHGSNTR"
     gene            complement(52122..54281)
                     /locus_tag="PK063_00225"
     CDS             complement(52122..54281)
                     /locus_tag="PK063_00225"
                     /inference="COORDINATES: protein motif:HMM:NF014893.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bi-domain-containing oxidoreductase"
                     /protein_id="HMZ95485.1"
                     /translation="MKQVIQNFRSGVLKIDDVPPPMLRDGGLLVMNHVSLISPGTEKS
                     TVQVAQKSLLGKAMERPEMVKKVLTAIQKDGLKDTLQRVFERLDTPAALGYSCAGTVA
                     AVGADASQFSVGDRVACAGQNYASHAEVVYVPKNLCVKLPTTVDFEDAACVTLGAIAL
                     QGVRQAEPRLGDRIAVIGLGLLGQLTVQMLKAAGCRVLGSDLDGTKLDLARQLGADLT
                     VRPSGLMDAATGFSEGHGVDAVIITASTKDNSPVEIAGAIARKKGRVVVVGAVGMNLP
                     REPYYKKELDFKLSMSYGPGRYDSAYEEKGQDYPYSYVRWTENRNMAAFLDLVGDGKV
                     QLKPLITHRFEISKADDAYRMMTEGQTPYMGMLITYPLDQQQALQPSITVVSDKPTGR
                     LTLGLIGVGNHVKDMLLPQLQSQAAVSIRAVCTASGINAKALGEKLHAGYCTSDSQDV
                     LRDPAINTVLIGTRHDTHGRLVVKALEADKHVFVEKPLCLTEEELDAIHAVYCDKAAK
                     GLRLMVGFNRRFSPHAEKAREFFAHRENPLVMWYRINAGKIPAEHWIQDPSVGGGRLI
                     GEACHFVDYMQSVCGARPNSVFARRIGRQSSGITDDQCIITLTFEDGSIGSIIYTAGG
                     NSGLAKERFEAHADGKSLTMDDFEETHLYSGSHREVFKTSKRDKGFKTEIAHFVQTVE
                     QGIPCVMSFGEIAAVTRACLLAVRSLQSGSAHDIAYV"
     gene            complement(54576..55265)
                     /locus_tag="PK063_00230"
     CDS             complement(54576..55265)
                     /locus_tag="PK063_00230"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95486.1"
                     /translation="MMKRALNLSLSLLVLAVGSVLPIGEETRAEAALVTYEFSGNISE
                     VPGSLFTSGGTGANGFNTGLKLSGTYTFDTAAAGLLPSSLPIQLYNNSVSSLNLSIGN
                     YSAVLQGGGTNLTTVSSGNPAFYSVNVGTAGNLVKGLAPSLFSINLADETGTAFSSVT
                     LPGNQAPNLNAFNVNRWTLAFSNGKTLVGSLDTLKAVPLPATVLLFGAGLIGLVGLGA
                     RGRFNQSSVRG"
     gene            complement(55550..57451)
                     /gene="asnB"
                     /locus_tag="PK063_00235"
     CDS             complement(55550..57451)
                     /gene="asnB"
                     /locus_tag="PK063_00235"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: protein motif:HMM:TIGR01536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HMZ95487.1"
                     /translation="MCGIVGFMAQDAESALTERTLTIMRDQMIHRGPDDGGVYVRREG
                     ASTIGLGHRRLSIIDLSPLGHQPMSTADGSLWIVFNGEIFNYRELRAELPARIQAQFR
                     SQTDTEVILYAIREWGLDGCLQRLRGMYAFAVYDSTSEILTLVRDPLGVKPLYYTHDR
                     GRVTFASEIKALAAMPGFKPVINDQALYHYLTFANAPAPQTFFEGILKLEAGTYLTCD
                     KKGSMRQHRYWNPSTFQPGSASLTEQDYVDELRRLLRQSVRRRMVSDVPFGVFLSGGV
                     DSSLNVALMAELLDRPVETFSIGIKDDPSNEFDYARQVAEHFHTNHHEAVISDEDFIR
                     FLPQMAYLQDEPVADPVCVPIYYISKLARESGTPVIQVGEGSDEIFAGYQTYHLFDDW
                     NRRYYEPYLQAPEFVRRAVYSLGSHVCSSEKQDALRRAMLGDPLFLGNAIAFWDNEKA
                     GLLHQAFLPRHTSSEYIRNLGGSLGIDDSLLKIIHVELKNRLPELLLMRVDKMSMANS
                     IETRVPFLDEDVVSFALTIPSALKYKQNQPKYILRQAARGIIPDSIIDRKKWGFCGSA
                     TNMLSTRLTDYARSRILDSPLMHERFDRNAIEVIFIALRQQKRFNSFKIWNLLNLVLW
                     YERWFASTR"
     gene            complement(57486..58355)
                     /locus_tag="PK063_00240"
     CDS             complement(57486..58355)
                     /locus_tag="PK063_00240"
                     /inference="COORDINATES: protein motif:HMM:NF024880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HMZ95488.1"
                     /translation="MNTLHDIEQFWDANPCGETLVGKDQEWATFFNRYDEFRYRTEGH
                     ILGELDRLQLAGKNVLEIGIGQAADSAQIIRRGGRWHGLDLTAEAVFRAKTRFELFQL
                     PYQAVKQGSATAIPYPDKSFDIVYSHGVLHHIPPIRQVSPEIRRVLKPGGKLVIMMYH
                     KHSLNYLVSINIVRRLLMIGLFGLAKIGARPLITHPLLAGHLQNAEEFGLWTYLQNPL
                     FMMRNTDGPGNPYSKVYDAQDIAADFAEFRLENTRVHFLNERHLPVLKLLPPRVRTYL
                     ASKLGWHLWATLG"
     gene            complement(58355..59530)
                     /locus_tag="PK063_00245"
     CDS             complement(58355..59530)
                     /locus_tag="PK063_00245"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HMZ95489.1"
                     /translation="MTTRNDTIEVIGPTPPPYHGVSVATQVLLDALPHSQLAVVHLDT
                     ADRRGIAHVDQPDLWDVFLFIRQWFAHLFILLRKRPRICYLPLSQSRVGFLRDSLFMV
                     PAFLTGSAVVAHLHGANFYQVYEGGGTAFKWYVDQVLKRVAKFVVLGDMLKPIFHRWA
                     SLESIAVVPNGVPELSTDGSPGPHCVRSAGPRIVFLSTLSRNKGLFVLLDAVPLVVQE
                     FPTAEFHIAGPWWGADTERLVRAQLEQGNVSSQVIFHGQLAGAKKMAFLRSGDLFVFP
                     GIQQEGQPLTVLEAMCAGLPVIATDRGCLRETVMEGETGFVVPPNSPTAIAERILLLL
                     REPHIRQRLGANARLRYEREYTMPLYAARMADLFAQVSQSDYHENPKSMDSRHWSIR"
     gene            complement(59527..60705)
                     /locus_tag="PK063_00250"
     CDS             complement(59527..60705)
                     /locus_tag="PK063_00250"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HMZ95490.1"
                     /translation="MKLAVLTNILTPYRIPLFQAMAEQVDEFSIILMAQQEENRLWKI
                     EDVPFPVYVLPGFHVRPWGAPVAVHLNYGVTARLTQLDPDVVLNAGFAVANIAAYWYC
                     RRAHIPFIHWAHLSLNDGAQASFVRRRIRHWLIGRSAGAVGESSHARDAFIHYGAPKE
                     RILVATMPLDVTGLHDRVLARKQWPETSTPLNTLSKPVLLSIGQLIPRKGYHELFAIY
                     ERLLTTHPHTSLLIVGDGPDRQHFETVVREKGWTRVHFAGFVQAQDLPRYFALSDAFI
                     FHTLYDPFGLVLSEAMAAEVPVVSSIHAMATHDLVEDGVTGFRIDPLQPEASAETVRH
                     LFDMSSDQRTSLIDAAYRRVLPCDSRTSASRIVEFLRSFRTPHEPRMATTPSPSQRIS
                     "
     gene            complement(60724..62250)
                     /locus_tag="PK063_00255"
     CDS             complement(60724..62250)
                     /locus_tag="PK063_00255"
                     /inference="COORDINATES: protein motif:HMM:NF024832.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HMZ95491.1"
                     /translation="MKKSDEHSHQGQTDQLVVAGSAVLLSSIFGNGLNYLFGVFLARF
                     LGADQFGLYALALAFFTTLTLVVPLGMDAGAIKFISEYRTRQDSEGAQRIVLMAGTVT
                     FLTAALTAICLAGLSSLISLSVYHKPELNILLLYVAAGIPLYALTSILLASLQSHHTV
                     RPLIVVRYLWEPIGKFILAGLVISAGWGLAGVFGALLIAMLVSLTLTLGFLRTVVRFR
                     RPMIDLWSREEAARLMTYCLPLGVATVFGVVAPRADILMLGSWVNVHEIGIYQAAFQT
                     AAALALILGALESSLTPFFGQLHAQNDIAGLRHMYQTASKLVLLFTVPLFVLLAVFSE
                     EVLSLFGTEFRAGGTLLIVLASGQLLSSAGGSPNNLLLMGGHSRLVMWNTIGVGLLAF
                     GVFACTIPLWGVLGAAIGAASTQVFGVGLRILQVWRIFHIQPFSQRLVKPLLAGLGSA
                     VLGLSLKPDAPALLLPGLGLMMGLVYIVLLIALKLDPQDRQALNALVSKAKMIVAVRA
                     "
     gene            complement(62396..63730)
                     /locus_tag="PK063_00260"
     CDS             complement(62396..63730)
                     /locus_tag="PK063_00260"
                     /inference="COORDINATES: protein motif:HMM:NF016800.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HMZ95492.1"
                     /translation="MAYAFGFLILALLVKDTAPIGDQYVLRTLSQGLCLTAGFWWLFT
                     QGNIIAMRRYWLILLYSAVLCSTAFVSMDSTRVLLQVLSLVAVTLFFMSYCEQAQQMP
                     SMHDTAARIVLYALLPVCLGSLLLYKIAPTLAFDQTVERMVWDNPHRFKGLFGKPAGI
                     AAASGILLGLCAFTKVHWLIRAVGALSSLMCLYLTLSRSFWVGSSVALLVTAFLYAKR
                     KGLLLGAGIGGLLLILATVSIMDTKIPGLNQSRSMRSDSLENLSGRTTLWTLALDRFW
                     DRPVLGYGYTVGHQAFLYSRKAKGADVAGDNVDLFRNETFSLHNGYVQALLDSGGMGA
                     LLYTIILAITVWRIVWYDRVKAHAAALYSLVFLSIANIGETLVYTPATFHAAFYWYVA
                     VLALGLRFTVEPPPASFAEPIVLPVRERTTKYPIVSRPEPQVQQGKTSPGLC"
     gene            complement(63851..65014)
                     /locus_tag="PK063_00265"
     CDS             complement(63851..65014)
                     /locus_tag="PK063_00265"
                     /inference="COORDINATES: protein motif:HMM:NF014675.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 10 glycosylhydrolase"
                     /protein_id="HMZ95493.1"
                     /translation="MLSRRQFLQISAACTASALCASLPRFAQAQETFESRVIFDESLS
                     WVTEHSAHSMCQRMKQAGFNVVMPCVWHGRGTSWPSNLAPWDSYKLDEMARWNSSFDP
                     LGKLVEIAAQYQIEVHPWFNVTLRQREFLPHFYGPGTPADAFDVHRPDFRTFISNLMI
                     ECVSRYPVHGINLDYIRSVSICQSPECARQYHHHTNRNLMLDRLSYGASADAREAIAD
                     WNEQAVGDIVRRVSSHLRKNQPNVLISLCGHPGHPNLYIQGQKSIKWADEGLIDVVYD
                     MRYPAEPNWEEIRSVQKTMKRPEAYAVLIGNYDLAGAHQISVSSSGARVAAQIVRSRQ
                     VAPGNGVGVYLYSLLNDEQITALRSGPFQTPASPKWSRAKGLDLSTPTGLLVQ"
     gene            complement(65018..66229)
                     /locus_tag="PK063_00270"
     CDS             complement(65018..66229)
                     /locus_tag="PK063_00270"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HMZ95494.1"
                     /translation="MSHVKSIALIQLHIPHYRVPLFAALQAEAARRGYALTVYSGEQQ
                     PMPFSHRKLSLRYLSHDKSGGCWMEGLAEAVAGSDIIIAPHGLQCLTIPFLWLQRNRL
                     CTSWIWWGHGYNFQASTQGSTAEWITSAIKNFLLTRGDGVITYTHGGAQYWCNRGLPP
                     ERVAPFLNTIDVEGLREARRQVTDDQLSLVRERLALGKKQVLLFSGRLYAEKQVDFLL
                     EAFSKIQQACPETALLILGEGQERARLEQLCSSLHLHDVHFLGEITDPHETSIYFKLA
                     ELLVIPGLVGLAIVHGFAFNLPLMTTERPFHSPEIEYLSSLNGRMTRHDTDAYAAEII
                     RVLSSPQEIEAMRWHCAESAQQLTLAASSSRFVQAVAQFSNPTGSLTSNRRRSQRTSF
                     SSSAATPSLRR"
     gene            complement(66723..67823)
                     /gene="wecB"
                     /locus_tag="PK063_00275"
     CDS             complement(66723..67823)
                     /gene="wecB"
                     /locus_tag="PK063_00275"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HMZ95495.1"
                     /translation="MTRIDLIAGARPNFMKIAPIIDALNAARSRGSHLRFRLIHTGQH
                     YDRAMSGSFFEELGIPDPDINLEVGSGTQAEQTSAIMVNYEKVLAKDKSHLCLVVGDV
                     TSTMACSIVARKMGIPVAHVEGGIRSNDWTMPEEINRVVTDSITNWFFTTSETANENL
                     RRAGVTSDRIFFVGNTMIDTLLKHADRLRPPACWSSLALKPNHYFVVTLHRPANVDGE
                     QQLLGLLRAIAEGTQGLPVVFPVHPRTAKNLRESGQALPSMHYVDPLGYLEFNYLVKH
                     ARGVITDSGGITEETTVLGVPCLTLRDNTERPETVTIGTNELIGTDPAKLPPALQRLM
                     AGQWKKGAIPPLWDGKTAVRIVEHLTTLLAKP"
     gene            complement(68018..68257)
                     /locus_tag="PK063_00280"
     CDS             complement(68018..68257)
                     /locus_tag="PK063_00280"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95496.1"
                     /translation="MTSLTRPVFLLMLCAFSAGCSTAEWVHPNRPKDQFTLDYNKCQA
                     DTMRDPKLQQGIQLLIIQATERCVQKQGWRLVEKE"
     gene            complement(68364..69263)
                     /locus_tag="PK063_00285"
     CDS             complement(68364..69263)
                     /locus_tag="PK063_00285"
                     /inference="COORDINATES: protein motif:HMM:NF024970.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ95497.1"
                     /translation="MIGHAASPTMLVVDASPETWAMALEEGKLRGISVITAPDPQVAL
                     AMIDMAAPDILMTDLFPADQAGVLLIRELRMRSPKTAILATGESGDAETILNVVRAGA
                     GDYLRKPLLVEELGLALDRALRQLPSTVENIAGVEQVDYRLVLGTNPDHVEACVTWLI
                     QQTALTLPEMQRLHLRTTLIELIVNAVEHGSLEILYQEKHAALSSDQFERLIEERRRH
                     PRFARRRVVVQASHDKTRRRLRYAITDEGKGFAWSRFVATPEQPCDSRHPNGRGVFLA
                     KAFFPDLTYNERGTEVTFSVPVP"
     gene            complement(69260..69619)
                     /locus_tag="PK063_00290"
     CDS             complement(69260..69619)
                     /locus_tag="PK063_00290"
                     /inference="COORDINATES: protein motif:HMM:NF013767.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hpt domain-containing protein"
                     /protein_id="HMZ95498.1"
                     /translation="MDSQPVMDLAAALDRFDGDQDLFLTLAGLFVERSGQALAALQTA
                     LSAQDLPVLVKEAHKLKGSAMEFCARPAVAAAAHLEEAARKAAAQDIPALAEQTRAEV
                     ERLTAALAEIMQKGFPS"
     gene            complement(69619..70884)
                     /locus_tag="PK063_00295"
     CDS             complement(69619..70884)
                     /locus_tag="PK063_00295"
                     /inference="COORDINATES: protein motif:HMM:NF018884.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HMZ95499.1"
                     /translation="MAEPARRIDPQSGTDSDAKPAPVILLVDDDEITRTGMAGRLKRL
                     GYRVIEAGDGTAGLTAIRAQRPDLVILDWMMPGMDGPSVCEAIRADPELKSSQVVLMT
                     AHDRPEQIAEGLSRGADDFLSKAASKQEVLARVQASLRSSALVREIEHTRDDLDRSHR
                     LLSAKQAELESELQSAADFVRAQLPLPGMPATGVSMQWAYQPSLALGGDLFQVCSWGA
                     DALGLYILDASGHGVAAALRAVGLMSFLREDNLAKVVGSFDPGAIITEANRLFPLTQD
                     GEYFTLWVGRLDISSRMLSYATAGHSGAFLQAAGDGSRWLSMASLPLGFDPHSVFESM
                     HTPLLSLDRLYLLSDGIYEAPSPTGELWGRDRLQATLEAHRSHSLGQSIADTMATARQ
                     WLAGEIFPDDVALLGLEMLDTLLGQKERA"
     gene            complement(70908..71258)
                     /locus_tag="PK063_00300"
     CDS             complement(70908..71258)
                     /locus_tag="PK063_00300"
                     /inference="COORDINATES: protein motif:HMM:TIGR00377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HMZ95500.1"
                     /translation="MQITERRVGESVILDLVGELTYANRATFKASVERSRAGGVRHLI
                     LNMQGVRFLDSSALGTLALLTQSLSATRGTIGLLNPQSYVKEILTLANLHQLLPVYHS
                     EQDALAACRLPKAG"
     gene            complement(71291..71629)
                     /locus_tag="PK063_00305"
     CDS             complement(71291..71629)
                     /locus_tag="PK063_00305"
                     /inference="COORDINATES: protein motif:HMM:TIGR00377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HMZ95501.1"
                     /translation="MKITSEIHNHKVTLKLEGNFTYTQRKPFQEMLKSVSVDPMEHIV
                     IDLSQVAFLDSAALGLLMISHRQLQAEKRTLSLAYPQATVRQIIELANLHKTIPLIES
                     PASTVTKKSA"
     gene            complement(71661..72707)
                     /locus_tag="PK063_00310"
     CDS             complement(71661..72707)
                     /locus_tag="PK063_00310"
                     /EC_number="3.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0008984 - protein-glutamate methylesterase
                     activity [Evidence IEA];
                     GO_function: GO:0050568 - protein-glutamine glutaminase
                     activity [Evidence IEA];
                     GO_process: GO:0006482 - protein demethylation [Evidence
                     IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0018277 - protein deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis response regulator protein-glutamate
                     methylesterase"
                     /protein_id="HMZ95502.1"
                     /translation="MAKIRVLTIDDSALMRQVLAELLSKDPGIEVIGSAPDPYVAREK
                     IKALNPDVLTLDVEMPKMDGLTFLEKLMRGRPTPVIMVSSLTEAGCQTTLRALELGAV
                     DFITKPKIDLREGMDQVAQDLIAKIKAAATASVRPTTAAASSTSRPTSLNSAMIKTTD
                     MIIAIGSSTGGTEAVKDVLQVLPPNTPPILITQHMPERFTKTWADRMNQLCRISVKEA
                     EDGDSVLPGHALVAPGNYHMTLVRSGARYSVRINQDEPVNRHRPSVDVMFDSVAQYAG
                     GNAVGVILTGMGGDGAKGLLRMKEAGAFTIAQDEASCVVFGMPKEAIKLGAADIVRPL
                     GDIASAILTQVTRA"
     gene            complement(72769..73386)
                     /locus_tag="PK063_00315"
     CDS             complement(72769..73386)
                     /locus_tag="PK063_00315"
                     /inference="COORDINATES: protein motif:HMM:NF015908.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95503.1"
                     /translation="MAIIDTDAFSHIRRMRDGRFPHEVACILPGEFFVSREPMVVYTV
                     LGSCISACIRDPIVGVGGMNHFMLPAPKEHQSGDAWGGESTRYGSFAMEQLINEILKR
                     GGLRHRLEVKLFGAGKIYDGNIDVGARNTEWVLQYLKTEGYALAKSDLGDVYPRKVYY
                     FTDSGRVLMKKIERVKNRTIYERETEYQHRIEVEPTVQQDNITLF"
     gene            complement(73392..74210)
                     /locus_tag="PK063_00320"
     CDS             complement(73392..74210)
                     /locus_tag="PK063_00320"
                     /inference="COORDINATES: protein motif:HMM:NF013867.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase"
                     /protein_id="HMZ95504.1"
                     /translation="MDYPISKKEYDQIRTLLYDESGISLGESKQSLVVSRLTKRLRDL
                     QLGDFSSYYEYVTEDNSGEEFTRMLDLLSTNKTDFFREPKHFDFLRERILPSLEKEKR
                     IRIWSSACSTGEEPYTIAMTLHEGVQQPAQWNFQILASDISTRVLAHAAKGLYAEDRV
                     REVPPEIVKHHFLQGRGDSAGLVKVKPHLSAIIKFRRLNLMDDHFPIKAPLDVIFCRN
                     VMIYFDRPTQERLVNKFYHHLKPGGHLFIGHSESLQWVSHPFKTIAPTIYWKES"
     gene            complement(74215..74676)
                     /locus_tag="PK063_00325"
     CDS             complement(74215..74676)
                     /locus_tag="PK063_00325"
                     /inference="COORDINATES: protein motif:HMM:NF016153.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF420 domain-containing protein"
                     /protein_id="HMZ95505.1"
                     /translation="MDVKTLLWYLVLSSLTVAYLVVLAGVKAAKSHDVTHHSHRMIVG
                     CTIVGIWLVAYVLKQALFGRESFQGPESAYWSVYVPIFVTHMLLAVTTIGLGAYNLYM
                     GLHRLRFGSVGAMVAGMTTHRRMGNALIWTFSGTMVTAYLVYLMLFVWYRS"
     gene            complement(74882..77332)
                     /locus_tag="PK063_00330"
     CDS             complement(74882..77332)
                     /locus_tag="PK063_00330"
                     /inference="COORDINATES: protein motif:HMM:NF012245.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HMZ95506.1"
                     /translation="MALQVELLESSFKLVAPKGEELVTRFYERLFKKYPAVKPLFKHT
                     TIKEQKKKLLASLVLVIQNLRRPEKLTPVLQDMGARHVGYGAKPAHYDAVGENLLAVL
                     GEVAGPAWTPQVKQAWTEAYGAIKTIMLAGAERVHNTQGEKTMSKPKGKKGTAAQADM
                     TEFYLGALDQSQNNILLCDRNLVITYANSTAQKTLATLEPAIKKVLPKFNLSTVVGTC
                     IDDFHLDPSKQRRILSDPANMPHRADIQIGPLTLSLLVTAVMSPSGEYLGNALEWADV
                     TEKRRLETEMSRLKASLDNARSNVLVCDRSYTIVYANNQSVTTLRRLETEIQKVMPAF
                     AVAKVVGSNIDQYHKNPAQQRTLLDNPKNLPYKTEIKIGPLTLDLAVAAIMNEKGDYL
                     GNVVEWADISAQKKAQVEIDKLIEAAASGQLSERINAAEFDGFFKTLSEGVNKMLDAV
                     VTPLHEAQTVLTAMAANDLTKTMTGHYQGEFEQMKSSLNGALNTLSTAISTVRDGAQS
                     VTAGAEQITKGNEDLSQRTSEQASALEETSASMEEMTSTVKQNADNAKQANQLAIAAR
                     DIADKGGSVTVRAVEAMGEINKSSKKIADIITVIDEIAFQTNLLALNAAVEAARAGEH
                     GRGFAVVAAEVRNLAQRSATAAKEIKGLINESIQRVNDGSELVNQSGKTLEEIVSSVK
                     RVTDIIAEITAASQEQAQGIDQVNKAIMQMDETTQQNAALVEETTSASQSMKDQAQEL
                     MRQVEVFKIEAGETQRQSNAHSSVGKSPAKSAIVATKPALKKPSFTARPADAKQPVGT
                     PAGNGHDRHKKDDDFEEF"
     gene            complement(77360..77869)
                     /locus_tag="PK063_00335"
     CDS             complement(77360..77869)
                     /locus_tag="PK063_00335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HMZ95507.1"
                     /translation="MASQESASKESNQQIGITTDGSQFLTFQLGEELYGVDILRVQEI
                     KGYTAVTRIPNTPPHIKGVLNLRGTIVPIVELRTKFGMPTIEYTMFTVIVVVVVKEKI
                     MGLVVDAVSDVLDIDKKDIQPAPQFGAQVDVSFLNGIGKAGDKLVALLDMDRLLTDGD
                     LQETEKVAA"
     gene            complement(77930..80053)
                     /locus_tag="PK063_00340"
     CDS             complement(77930..80053)
                     /locus_tag="PK063_00340"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HMZ95508.1"
                     /translation="MSTDLSHFKNAFFEESQEHLTTIEEGLLQLEQRPGDIDLLNRIF
                     RGAHSIKGNSGMFGFTAVSQFTHKMESVLDQLRSSQMVVTVEITDLLLQSLDCLKTLI
                     DCAKTGESPDEDQIARLGAQLEACQGGTPAATPSAAAASPRQSQVAGTHHFTITWVPP
                     RYLFQRGLDPVQFIKELGDLGSVTSVTLDPSRLPALKDLDPEQCYLGWTIEMDTVKDL
                     KVIEAVFDFVREDSTLTIVDTPPPAEESHGSTEGTKPLGEILVETGVVSQSQLNQALS
                     QQKRVGEILVEQKIATPEQISEALKKQTESSTPSKKAETPSIRVDTVKIDRLINLVGE
                     LVITQSMLSDLGSRFDMSQLPVLLERVAQLERNTREIQERVMGIRMVPIGNAFSRFPR
                     LVRDLSGKAGKKIHLILSGEETELDKTVIESIGDPLTHLVRNSADHGLEPPDERLAAG
                     KSEQGTIRLNAFHEGGNICITVEDDGRGLNRDKILAKGIKQGLISETEKLSDEQIWML
                     IFKPGFSTAEKVTDVSGRGVGMDVVKRNIEGLGGTVSIKTSAGKGTTFTLKLPLTLAI
                     IEGMTVRVGRDTYIVPLLSILESIQPKREMIKTIVGKGELVNVRGTYLPLMRLYDVFR
                     LEPELSDPTKAILLILETEGERVAVMVDEILGQQQVVIKSMEQNFRKIEGVAGATILG
                     DGTVGFILDVRGLLNIARQRKAKAA"
     gene            complement(80148..80519)
                     /locus_tag="PK063_00345"
     CDS             complement(80148..80519)
                     /locus_tag="PK063_00345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ95509.1"
                     /translation="MAKTVLVVDDSPTMRQMVAFTLTNAGYQVVEAGNGKEAVGKVNG
                     GAKPDLVVTDLNMPEMDGITLIKEIRKMPALKFTPILMLTTEASDDKKKAGQAAGATG
                     WIVKPFNPEQMMAVIKKVLPG"
     gene            complement(80557..81672)
                     /locus_tag="PK063_00350"
     CDS             complement(80557..81672)
                     /locus_tag="PK063_00350"
                     /inference="COORDINATES: protein motif:HMM:NF012245.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HMZ95510.1"
                     /translation="MILHWLFLLCAFLAGAFLSWMWCQRRAAAAQQALEAAQQHILKQ
                     HMDRDAIWEQLGHSIIPLVAVLNAQMKSVINQTEQAATDLGQRFSTIASRASFQANES
                     MNLFGDGEMNLDTVLKTTDTMLEGFVSDVMKSSEMALQIATIMDEVERSTKAITGMIG
                     EIEFIADQTRLLALNAAIEAARAGEHGRGFAVVADEVTKLANRSGQAASSINTMVKDV
                     QRSTTQAMQTVESLASVDLSKTLSIKHRLDQMTRNLADRNKTLHSAVMNSKSHSDELS
                     KDVGHIIMSLQFQDITRQKLEHVIEPLTEVRDIMDALIQRHPDDQIAARMNILANLDR
                     SYTMEEERAIFNQSTNGQVSGNAQISAPSEDANVTLF"
     gene            complement(81714..81944)
                     /locus_tag="PK063_00355"
     CDS             complement(81714..81944)
                     /locus_tag="PK063_00355"
                     /inference="COORDINATES: protein motif:HMM:NF024857.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HMZ95511.1"
                     /translation="MTLKPVGDLTIFEVGALCEEVKQAAATHPQVEIDLSEIDKLDAA
                     ALQLLIAVRRSEHCVLTGMTDPIRTRMTELGA"
     gene            complement(82070..82843)
                     /locus_tag="PK063_00360"
     CDS             complement(82070..82843)
                     /locus_tag="PK063_00360"
                     /inference="COORDINATES: protein motif:HMM:NF012894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein MotB"
                     /protein_id="HMZ95512.1"
                     /translation="MAKKKHEEHENHERWLVSYADFITLLFAFFVVMYSVSSVNEGKY
                     RTVSDSIKAALNPVNSTPSSRLPFAVGDSKPKMINTDMSSPNDPVIRRMKEVIKKIHP
                     SLALEMPDIKIIETGNGTIMISLPESILFGSGEARVRPEALPFLKSLAQILIEMDRHI
                     RVLGHTDNVPIRTAQFPSNWELSAVRAVMVVRIFSELNEVPISHLSATGFADSKPIAT
                     NDTPEGRTKNRRVEIIVLEKNLTEESLDSVLPNPGPPAL"
     gene            complement(82927..83697)
                     /locus_tag="PK063_00365"
     CDS             complement(82927..83697)
                     /locus_tag="PK063_00365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HMZ95513.1"
                     /translation="MDIATIIGIVVALGSIIGGQALEGGHLGSILQLTAFIIVAGGTF
                     GACCVQNPLSVVIKAATGATLVITNPPHDVKGTITQILDLANVARKQGLLALEGKLKD
                     LHDPFFKKGIQLIVDGTDPKLLQEILEIEVEHHEEEGVHAAKVWEAAGGYAPTVGILG
                     AVLGLIHVMENLADPSKLGGGIAVAFVATVYGVGLANLFFLPIANKMKFKLKEEAGLR
                     TMVIMGLVGLAQGENPRLLQEKLESFLPPHERTKEDKK"
     gene            83828..84070
                     /locus_tag="PK063_00370"
     CDS             83828..84070
                     /locus_tag="PK063_00370"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95514.1"
                     /translation="MGPADSLILDAKQAILDEQHRKFQVLQKEGRWTEAMQQFHVTLN
                     CASDVLAESIQLLERVLDARNRRGPSLPDSPDVPQS"
     gene            complement(84124..84642)
                     /locus_tag="PK063_00375"
     CDS             complement(84124..84642)
                     /locus_tag="PK063_00375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HMZ95515.1"
                     /translation="MSATEQQVQSHIQAAAENSADRLVEKSADDLLQFVICLIGSEEF
                     AVDVLSVQEINRIVEVTRVPKTPPYVEGVINLRGRIIPVLDLRKLFGLTGAQQTTQTR
                     IVVVSVQARLVGLIVDSVEEVLRVPKSAIEPPPSVGTMAGAEFTQGVGRIDDRLLILV
                     DLSRLLLAREAA"
     gene            complement(84670..86346)
                     /locus_tag="PK063_00380"
     CDS             complement(84670..86346)
                     /locus_tag="PK063_00380"
                     /inference="COORDINATES: protein motif:HMM:NF012245.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HMZ95516.1"
                     /translation="MMKHMSIGPKFIISISAVALVVITLGLVVLYQQEETKIDTLLTG
                     RMNVVSTQIMISRAYITQNYVAKIKKSKAGNEIQVLKDHTGVADAIPFPATAVREMGE
                     EANRTGLYNVRLISQNPMNPSNTPKDNFENEAIRAIMSGAESYARRDEVNGVPTFRRA
                     TVDKATSTACLSCHTNNQVGDVLGMLSMSVPMTEAIALSNRSMWQTGGLMGAIVAIIL
                     VVMYLLLRNIVLQPMAKMSEISRDIAKGEGDLTKRVPAEGHDEIAQMGQYFNEFIEKL
                     QHMIKKVAHVTDKVASASVELSATAEEISKGTDTLTSRASQTAAAVEEMNATVGQVAQ
                     NSGKAASLAQDTVKTAQEGGTVVSSTISGMQQLSEAVSNSATIISDLGKSSDQIGEIV
                     RTIEDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLAERTTKATKEIGDMIRQ
                     IQQDTRGAVDSMQQGTQKVTAGVDLVNKTGEALSQIVRMVSESADMIRQIAVASEEQS
                     VATQQIASDIENVAKVTKESSSGAHESAKASQDLSQLAVELQGIVGGFKL"
     gene            complement(86404..87501)
                     /locus_tag="PK063_00385"
     CDS             complement(86404..87501)
                     /locus_tag="PK063_00385"
                     /EC_number="3.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0008984 - protein-glutamate methylesterase
                     activity [Evidence IEA];
                     GO_function: GO:0050568 - protein-glutamine glutaminase
                     activity [Evidence IEA];
                     GO_process: GO:0006482 - protein demethylation [Evidence
                     IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0018277 - protein deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis response regulator protein-glutamate
                     methylesterase"
                     /protein_id="HMZ95517.1"
                     /translation="MALPLTQPQSAAKPVRVLVVDDSAFMRKSLTTMLEEGKQIQVVG
                     VARNGEEAVQQVQQLKPDVVTMDVEMPGMTGLQALQQIMTKNPVPVIMVSSVTVEGAQ
                     ETLQALEWGAVDFIPKQLDGVASKIAEIQKILVPKVLAARYAGSKLKRLNVTGAPKLA
                     VPAAKALSSRSVSVTRGTKLIAIGCSTGGPQALFEIVPTIPADCPAGIVIVQHMPSSF
                     TKPFAERLNNLCALEVREAVDGDEVKAGRVLVAPGGMQFRVVKKSITTSVVKLSPNYE
                     RHAHSPSVDIMLQSVAALFGERSIGVILTGMGHDGLEGMKAIKAAGGRTVAQDEASSV
                     VYGMPKAVVEAGCAEKVVSLSKVIGEIMNMV"
     gene            complement(87582..88565)
                     /locus_tag="PK063_00390"
     CDS             complement(87582..88565)
                     /locus_tag="PK063_00390"
                     /inference="COORDINATES: protein motif:HMM:NF013731.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HMZ95518.1"
                     /translation="MSTLINEIDARTRLAGANQMELLLFKLGTNEIFGINVFKVREVM
                     KLPELTQIPEADNRIVGMANIRGIMVPVVGLKRSLGLGMETEGQGNGAPGGNPYLIVS
                     EYNGSLQGFLVAGVDRIIRFSWSAIKTPPAIVRENNKGAVTAVTMLEDGRMVLILDVE
                     KVLNDICPRTDDDVFAGMTIAPELRSKCVLFADDSSVARMQIRKALDRLSMSYVIATT
                     GGEAWQKLQALADQATAEGKEQVDQIQCILSDIEMPEMDGFTLTKHIRADPRLAHLPV
                     MLHSSLTGACNMEKGRTVGATDYITKFDAKMLGEKLALYIQNPNANVKKAA"
     gene            complement(88651..90543)
                     /locus_tag="PK063_00395"
     CDS             complement(88651..90543)
                     /locus_tag="PK063_00395"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HMZ95519.1"
                     /translation="MSDEMQEILNDFLTESNEMLEVLDQRFVTLESDPNNTDLLNEIF
                     RAMHSMKGSAGFLGFNHLVDVAHRGENILNKLRQGEMAVNPAIISIILETIDVIKAIM
                     ADIRESGTDNHVATASIAAKLDDILNGNTAPAAAPVQTEAVAPPKVEAASSAPAAAAP
                     VAAPQTLGEILVNDGLASKEQVLDALTAQQHQPEPKTPLGEILLQAKAITERALDQAL
                     HKQDKQPKPVEEDATIRVETKRLDSVMNLVGELVLGRNRLIKIGTQLEQQHESDPQVR
                     VLSETLAQLNLVTTDLQLAVMKTRMLPIKKVFAKLPRMVRDLSQKLNKQVHLEMRGEE
                     TELDKSVADEIGDPLVHLVRNAIDHGIETPAERQAKGKAGEGQLTIAASQEGNSIVIR
                     INDDGRGIQVEKVKEKALAKGLISEAELATMEHREILNLIFLPGFSTAEKVTDVSGRG
                     VGMDVVRTNIRKINGSVDLESEPGKGSQIIIKLPLTIAIIQALMVEVERSIFAIPLST
                     VIEAVRISRSEIKTINGREVLHLRDRVLPLIRLAQEFDIPTDANRERFYVVVAALGDR
                     RVGVVVDELRSQEEVVIKSIWDYLETVKGVSGATITGEGKVVLILDTSELVQNAQAWH
                     NPGIAA"
     gene            complement(90552..91202)
                     /locus_tag="PK063_00400"
     CDS             complement(90552..91202)
                     /locus_tag="PK063_00400"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF016247.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0050920 - regulation of chemotaxis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase CheZ"
                     /protein_id="HMZ95520.1"
                     /translation="MAQPRAAAQSQPATHESEQEEKAPDTKLYEELGELARFIDTTMK
                     TLSEFSTPVSTSTEQLPQALSHLTNLKTMTEQGTHRVMLEVEAIQDNHMKISGMIKDL
                     TLAMQKAQAAPALLQQMQAVGNAINVDDKRLLDIMTALSFQDLVAQSVNKLVTILQEV
                     EHKLLQLVVVFGPYQKQAAKKEQDKASEMLKQLEATKNTSMNQDLADEILKQFGFN"
     gene            complement(91229..91609)
                     /gene="cheY"
                     /locus_tag="PK063_00405"
     CDS             complement(91229..91609)
                     /gene="cheY"
                     /locus_tag="PK063_00405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014960018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis response regulator CheY"
                     /protein_id="HMZ95521.1"
                     /translation="MPADPNMKILVVDDMSTMRRIVKNILKQLGFNNLEEAENGQEAL
                     TKLKADTYGFVVSDWNMPVMMGIDMLRAIRADESLKKIPVLMVTAEAQKENLMEAVQA
                     GVSNYVVKPFTAETMQDKINKIFK"
     gene            complement(91619..92482)
                     /locus_tag="PK063_00410"
     CDS             complement(91619..92482)
                     /locus_tag="PK063_00410"
                     /inference="COORDINATES: protein motif:HMM:NF013867.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CheR family methyltransferase"
                     /protein_id="HMZ95522.1"
                     /translation="MAESNAVRKTEMPAPKLSPDTFKQLRDLIYEMTGIHFQDNKTYL
                     LESRLLPRLKACRCQTFESYLNFLRFDAYRDREITELYTVITTNETYFFRDEAQLDSF
                     MKVMIPEVMKTNAQTKQLRIWSAACSTGDEPYTLALLLRDYPPLNGWTIDILATDISE
                     NVLNIARTATYSSHSLRKVPPAMLARYFTGKKEEQTLVQPVKDMVRFMNVNLYDRPRL
                     KLIRGIDIIFCRNCLIYFDEKAKAQIVSDLRDALRPKGYLMIGFSETLHDAAGHFKTI
                     HAGRSVIHEKQ"
     gene            complement(92588..92818)
                     /locus_tag="PK063_00415"
     CDS             complement(92588..92818)
                     /locus_tag="PK063_00415"
                     /inference="COORDINATES: protein motif:HMM:NF024139.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HMZ95523.1"
                     /translation="MNNAIAPTTNVNFDSVSPSEGEILTVSDVARFLRVPKSTVYKLA
                     RLGELPASKIGKHWRFLRRDIHEWMHSRTQQH"
     gene            93007..93936
                     /locus_tag="PK063_00420"
     CDS             93007..93936
                     /locus_tag="PK063_00420"
                     /inference="COORDINATES: protein motif:HMM:NF013793.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-loop NTPase"
                     /protein_id="HMZ95524.1"
                     /translation="MATIVSIGSGKGGVGKSVIAANLAMLLAKRGKRVVLADLDVGGA
                     DAHILFGLLNPPRTLTDFVERRVERLEEVLQPISAHPFLQLLPGTGDTLATANLPYAK
                     KKRLIRHFSQLQADVIIVDIGAGTSYHALDFFLMADCYLTVATPDPTSVLDLYRFIKL
                     AAIRRVLSAFLSRDAVSEALSDRDFASIDEVIQAVGETDPNAKETASNTLQGFQPYLI
                     VNRVSGKSRVNVLQLKKLLKEYVGGDLTMLGEIPDDPAMVRAVRSYLPVVEFEPTAPA
                     SVALNGAADALLAQLTKPATMPQPSAPSPERAA"
     gene            complement(93967..94587)
                     /locus_tag="PK063_00425"
     CDS             complement(93967..94587)
                     /locus_tag="PK063_00425"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ95525.1"
                     /translation="MRPSPERPLQRPHHDIKNEERREWLRIDDRLLLEYRRADEPLEA
                     MNQYLPPATEDTIATAVSKPTVDLLVRAGETFAGSPLLPWVSKIDWMLETILKSMVKS
                     HPGSVSIARLTDVDISAGGLGFNTPREFQADDLLMLKVILPPFSMIETMAKIIRVTPL
                     DEGKAGFHLATQFVDLGGDEQELIIRHILQIQAERLRTRKAAHNHL"
     gene            complement(94645..94986)
                     /locus_tag="PK063_00430"
     CDS             complement(94645..94986)
                     /locus_tag="PK063_00430"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95526.1"
                     /translation="MSPSSSHPGSPHDRRSIEQLTIQALNAARAGDWDQVDACYSERG
                     LSLAACKPDHTVAQQLLIMDEEIRQAILLAQAGISALLAEASHVTRHLRQLRESSGQL
                     ASDSVTIHREA"
     gene            complement(94976..95365)
                     /gene="fliS"
                     /locus_tag="PK063_00435"
     CDS             complement(94976..95365)
                     /gene="fliS"
                     /locus_tag="PK063_00435"
                     /inference="COORDINATES: protein motif:HMM:TIGR00208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HMZ95527.1"
                     /translation="MIATAANAYQQTQVMTASRVQLIVLLYDSAIQSMELAREAILTN
                     NYKDKARFLDRSMAIVGELSSVLDFERGGEIAVSLHRLYDYMVQQCIQANLRHNGKHL
                     DGPIRCLTTLREGWQVVARQEAVAHVA"
     gene            complement(95381..96775)
                     /gene="fliD"
                     /locus_tag="PK063_00440"
     CDS             complement(95381..96775)
                     /gene="fliD"
                     /locus_tag="PK063_00440"
                     /inference="COORDINATES: protein motif:HMM:NF018852.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HMZ95528.1"
                     /translation="MAISFGGLGNGVDFGQVVTELAKVQRVPIDALNAKKKDLQTKLT
                     DYGTLGNKLLALQSAANALRLPNSFDRTTTTVSNETKLTAQAGVGAATGSYTVQVTQL
                     AKAHQITNSTAKAVAATTTPIVSGGSGTFTFKVGTGANQTVTLNDGATLDDLRSAIND
                     LGAGVTASVINTGTVSTPAYRLTLTATATGAANAVTVVTDTTSLDFTNTSGTGGTSTL
                     QAGQNAIVVIGEPGQTTISIERESNVISDAIPDVTLTLKSKTVTTPTPEPVTVNITTD
                     PDSVKTNIKALATAYNDIVKFVNERTTYDISTKTGGIFFNESTAKSVLSQLRTALSGE
                     VSGLSTYKSVGTVGFKTERDGTVTVDDAKLDAALASNYSATKALFVTQTTSSGIADRV
                     VKAVDFLDAIDTGAFTVRKTAITSQISKLTDEIGRKEDIASQYEERLRLQFASLDALL
                     QKLKGQTSALQALQ"
     gene            complement(96803..97162)
                     /locus_tag="PK063_00445"
     CDS             complement(96803..97162)
                     /locus_tag="PK063_00445"
                     /inference="COORDINATES: protein motif:HMM:NF015602.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlaG"
                     /protein_id="HMZ95529.1"
                     /translation="MVHDVSNYKDLPAAAIQATQSGPQHTTEKKVEAKAPEPESSTPE
                     TKGKDLEQALTRVREVFKKADSRLEFTVDPDLDRVVVKVMDGDSGTVIRQIPQQEVID
                     LAKRLETPTGLLLHHKV"
     gene            complement(97228..98055)
                     /locus_tag="PK063_00450"
     CDS             complement(97228..98055)
                     /locus_tag="PK063_00450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HMZ95530.1"
                     /translation="MALVVNTNVASLAAQRNLAVNQAQLGRSVERLSSGLRITRAADD
                     AAGLGVSETLRAQIRSINQANRNAGDGISLTQVADGAAATIGSLLSRMRELATQSASG
                     TLGTTERSYLDQEFVALRSEIDRISTTTEYNGQPLLSGSSNTFEVFIGFKSGSGNSLS
                     VALDDLDVAAVGLTGASVSTATAAQSMLAKIDSAISAVATARANYGSIQSRFEVAIQN
                     LTVTAENFTAAESRIRDADIAQETSVFTKNQILTQSGIAILAQANSLPQQALALLRG"
     gene            complement(98292..98834)
                     /locus_tag="PK063_00455"
     CDS             complement(98292..98834)
                     /locus_tag="PK063_00455"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95531.1"
                     /translation="MHITLDGEQLQVPEDTSMMNALATLSDKAHAKHHIVTSLTIGGK
                     TISDRDLTPPFLNQPVRDAGAIQAISQSLHTIILEAKQAIERFAAELRSDGQVLLAPL
                     RSGTAQVGTIDAWLGRLADYTEMLEAGQAQGVEGLSSASLLPWIQELLGARTTADAIR
                     VADLLEYELLPRLADARLAA"
     gene            complement(98877..100553)
                     /locus_tag="PK063_00460"
     CDS             complement(98877..100553)
                     /locus_tag="PK063_00460"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013257.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 9 protein"
                     /protein_id="HMZ95532.1"
                     /translation="MNKRVLLINITRMGDLVQMGTLLQRLQHEWPGAEVDLVVDQRFA
                     PVAKLLPHLRHIVEYDFHRLVDESRAQTKDVVTLYHDMTRWAAPLVEARYDRVVNLTF
                     NRRSGLLTSYVGAKEIRGIAAPKDGDVTIHNPWMAYLTDVHHERRFNHFNLVDIYALG
                     GSGSGPFAPLSLTIPPDTAEWARNFLATQGGQVRSWIAVQVGASDPMKAWRPELFGQT
                     LAALSRQTTAGYVFIGTEEERKAIHLAQTTYRKSGGTGPLCDAVGKTSLPQLAAVLSQ
                     CRLLLTNDTGPMHLAVGVGTPVIDLSVGHVDFRETGPYGPGHWMVQPDLGCAPCGFDQ
                     VCFHHACKDRIVPDQVAALCLHVLAGVPFPRSISGVRIYRSCADEDGLGNTELQAGRE
                     DLLVDWYGRFWRRFWFEEFTGRPSRVPCDHEPSPDCSDALAVLEHLKPLAKKLVSNAE
                     ELVRLTTKRPLPVSALQQMQRLETAERQQIVALSMQSPAAASLAVAMVRDTHNDDGHE
                     LTGLAQSRLATYRRWHKRLQAVSNSFRSFTAAQGSVRRGKTRQLPMARSA"
     gene            complement(100550..>101517)
                     /locus_tag="PK063_00465"
     CDS             complement(100550..>101517)
                     /locus_tag="PK063_00465"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024914.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HMZ95533.1"
                     /translation="LTAMWFVENYRHLTYWQQLAPGYEFWFVFQQGACLDAFRQAGAR
                     QVNYLPMAADAELHCPMSLSEEDRQRFGADVSFVGAGYANRRRLFPALLRQPWSFKLW
                     GNEWDGADDLRSVLQLDGARIDTATCMKVFNATAINLNLHSTTGAGLDPQADFVNPRT
                     FELAACGAFQLVDHRSQLRQFFTEQEMVSFQDFGDVPGLVQQWLNDHAARQAMANAAR
                     AHVLSEHTYVHRMRDLLGHIGLSQPDRVGSVLRGERQQESLVKRCADDRPLEALIQDC
                     PGGQRIELKDLAARIRSKGPTATLKREELMVLMLDEYRSETRDLL"
     assembly_gap    101518..101617
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<101618..102522)
                     /locus_tag="PK063_00470"
     CDS             complement(<101618..102522)
                     /locus_tag="PK063_00470"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95534.1"
                     /translation="MNMFQDNLNRLASRHRDLAAAVKSAAGGVLTIEPARTGLPSARR
                     SGRWIHSAYDPLREAQTWADTHAAACKSGEMVVVAGVGLLYHVEALRKKLTTDVSLAV
                     LLPNLDEFHDALVTRSLEGWSESILWLPGTPAEIAETLATIGRPIRCLSYTPAALADA
                     EFHRAVEDALRQGIARQAGGQLTIALVGPIYGGSLPITGYVKRALETLGHKVQLIDHS
                     IHAASYEVMGALKDPRNRQLMQGRMADVLSQWTLATLAESPPDLVLSMAQAPMTLQVL
                     EHLRKKKFLTAMWFVENYRHLTYWQ"
     gene            complement(102519..103712)
                     /locus_tag="PK063_00475"
     CDS             complement(102519..103712)
                     /locus_tag="PK063_00475"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013257.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 9 protein"
                     /protein_id="HMZ95535.1"
                     /translation="MPHEPSPAPRDLVIQMARLGDLVQTLPAIESLQEAYPKRTLDVL
                     CAAPLSSLLAGVSHIGRVIPWDGAQWRDWATGWPENPTVTLQVMQQYLASLGDTTYER
                     VYPLNQHERSHLMTQLFLSHSTREQEHDRMEARILPWAQHLRHVARERGANRVHLADA
                     WCGMCGVLPRGQAPSCEPPPVELPQDLAEIGERQGRWIAVVTGAGEADRCIPPAVWSQ
                     WIREFLAQTQDGQVVLIGSGTERETAQAILDSVPTLLHGRVWDATGRTTISQLMRVLQ
                     QCHWVIGADTGPLHLGTLAGARALGWYFSRARMHETGPYGEGHWVYQHATQAQPQRWP
                     IQESIALMCGDQGRRATDWTLWRSGMDRWGAYFDDGSGSATVESSRADIWRACAPALC
                     ESMAA"
     gene            complement(103702..110238)
                     /locus_tag="PK063_00480"
     CDS             complement(103702..110238)
                     /locus_tag="PK063_00480"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF025025.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HMZ95536.1"
                     /translation="MTPRPPMKVLLLQLEFPTWKQARAWTYPACFGVAEGLRASGVDC
                     TTLPLIADPPYSSTAWLAHMKRMLKGQRFDQVWVWLVHAPLDEAILNWLSELAPIRVG
                     IIMESLQYSEEDYAWAPHLRARQGFVEQQVRALTHVLVPDECDVERTAARTGVPALWF
                     PPMVPERFISTPQNAPVHRVGVFHGVPYGPREQWIHHPALKSCLTFARPSAPTLFQQL
                     FDRLQQSAIQRLATPAGMPAAELTHYTTMLQEVREGEFREWMTQLPLWAAIVNLPSLA
                     KFFGGRVFEGIAAGRPVVSYAVPGHPMNNSLFVEGEEILYFSPSRPDSLAEVLDRLLA
                     DDTFATRIAGNAQHKLRTYHTSERRLVETLAWIQSGTTPVYGEREAGAAYMLSSAKTG
                     HAAPSVEPRPTQAIGHVDTTIFILTVDDPAYPACKAAVDAQQGGPFHVEIIRNVAPFS
                     AAAQRMIADCRTEFFIQVDEDMILNLDAATKMTDLMRRAPSEVGMICFHLYDEDRACR
                     IQGIKIYRTAAMKPFAFQNVKASEMDLLEQMGQRGVRWVLHPDVLGRHGTVYTPETIY
                     RRYKTMYEKDIRQWNTLTSDIRRKADQFRATGDLLALFALLGAAHGIIESPRSADREK
                     DARAYGLNELDIFARLFRQTPPASQPYDAKRSGTPVANSPLAPEEVRWGGEAAIGNAP
                     DQQAFQRATPAAQPPRHHAARILIVTPYFWPSVGGVEKVAESLAVGLQSRGHAVEVAT
                     YALTERSAQSHRGIPIIDLTFPADFETTSPYSMLEVKRLIESGHYGCCILLGAPLHLM
                     FYAALAIPKDRPVRFILQPTINKEIAESLQGSEQGRTMLSQLGQRVNAVVTFGGNGYD
                     EQFFQERRIPTCVIPNGTPALAPKNDFRQRYGIARDTFLVIHLANLYKVKNHPGLLDA
                     LDHLPNGVQLVLIGNDTHETEYVETVKARLKTRPDVRLLAGLEPADVASALAAADLVV
                     LASHAEVSPLCLLEAMSVGRPWLATPDCGTAAEHAGGLVLPLSQFASTVGLLKKHPEL
                     CAELGRLGREHWAQSHDWATVLTAWEDLIEGRPVSHSFGTPVSIAERRETLREAFRRL
                     LAQEGTAVASTASTLQVETKGVVMDGLNQGPRGSVDRLAISNSAPTPQEQKQQDQFYI
                     DMFVKSRGWSSPGPNHDEAARWSKIAAFLEYLLRRVRQTDPQRQLRMLDVGCGRGWLT
                     NLATAYGTCEGIEPVAGVIEHARRLFPHLRFEAGTAQSVLSRPDFAPYDVILCSEVIE
                     HIPHGRKEGFVAELSMLLKPDGYVILTTPRGEMWEQWKTIAPPCQPVEDWVTEAQLRD
                     IFTSQGFCELGLERVHCELPSLRYIPAPTPADFHKLNLVPIYQIWACQRRGASPVPSF
                     TRPPMVSVIVPTYNRPDRLQVALSSILAQTYQDFEIIVVNDGTVDVSDVIAPLNRDGR
                     ITVIRHDRNRGLAAARNTGIRAAKGTYIAYLDDDDTYLPDHLQTLVTTLQGGEHKVAY
                     TDAWRIHEVRQGDQYVVTGQDIPYSRDFNCIDLLLCNYFPVLCVMHEKACLEQVGVFD
                     ESLFAHEDWDLWIRMATIYPFLHIKHTTAAFTWRRDGSSMTSSTSDTYRRTTEIIYRK
                     YRPYAERIAGVLEAQHKKLEGMRSDAQAKTFDCSIIIPVWNNLALTTQCLTALAEVTQ
                     GVSYEVIVVDNHSTDDTPAFLAGLGGDVKIITNNDNLGFAKACNQGAQAAKGEYLVFL
                     NNDTIPQAGWLSALVEEVKAHSEVAVVGSKLLYEDGTIQHAGVAFSREFLMPYHMYPG
                     VPADAPFVSRRRELQCVTAACMLIRRQVFAQVGGFDEGYKNGFEDVDLCLKVGEKNWK
                     IVYQPQSTVIHLESRTPGRKAHEEENTLRFRERWGRCWWVTDEDRLHFDDGYSVHTHL
                     KDGLLGYTLYLITDPAIRAERAFVADVQRATAVKDQQKIVSLLKRIEQWPTDAWILRW
                     GALLSEGIGHLELALSFWKRVISLKNDPQARLALAKQALESGAMKEADHHVTALLQAE
                     PSHGEGWLLRGILAMQLNAYRDAEQAFEQAKQAGAHPRKAMLGLVMAAMGDNRPEAAW
                     SHVAGLCADYPDDEECMHWMLKCGTLLQRWDALATRLSSFVARNPGNIAMRFALAGVL
                     LRAGRRADAQREYDWLRAMVPTFEGMDELAKQLAESERPLVPNHAA"
     gene            complement(110260..111885)
                     /locus_tag="PK063_00485"
     CDS             complement(110260..111885)
                     /locus_tag="PK063_00485"
                     /inference="COORDINATES: protein motif:HMM:NF015983.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HMZ95537.1"
                     /translation="MNVLLLYPTWTGAYGLFGHFARRNSTWPPLNLALLAAIAERHGH
                     NVTILDGESEQVPLEEMVQRAVAMKPDLIGFTATSPFFHLSKTVAEGIKRLAPEIPIA
                     VGGPHITIMKEQALLGCFDYAFIGEAEESWPQFLNAYEQRKDLSTVRGIIYRRNGELV
                     STGQPADITDLDALPIPARHRLPMSRYKLGTLRGRLPFTSIQTMRGCPWKCIFCASEA
                     LKTTEMRVRSPRSVVNEMKQVVEIFGTRHFYIVDDVMTLWKDHILQICDLIDQEGLQI
                     TFEGSTRANLVEEDVIARLVKSGLIRLSFGLETVDPEIRRTMKKQVPLEHYVKANGIC
                     NRYGVEALNSVMIGLPGETRETVRATLNFLRQAREVKQANFAIAVPYPGTEFHKLAVN
                     GEKGVRLMTQDFSEYRRYGSAVTTVGELTPHDLIDLQNEGFVSIYSAPWRWIPMLQKH
                     GMIGGSLMLVRVARLLSKKLFAGHGQSSQEQLISLGDGAFGRIQESAMSSQPVGVAPT
                     GPNSSAPLLTIASSSRAGAAPAGHFGHPTNPNG"
     gene            complement(111957..113795)
                     /locus_tag="PK063_00490"
     CDS             complement(111957..113795)
                     /locus_tag="PK063_00490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-binding protein"
                     /protein_id="HMZ95538.1"
                     /translation="MIKVADFIINTLAERGIDKMFVVYGAANGDLIDAFTRTAATQYV
                     AVMHEQAGGFAAEAYAKVKGIPGVAIATSGPGGMNLLTSMGNCFYDSIPCVFLTGQIN
                     SRFLRPDPSIRQIGFQETDIVAMASPVTKYAKMILNPEDVRFELEKALWMCQEGRPGP
                     VLLDIPLNVQKAMVDAKQLTGFEPPAAMSFDLTVVDQQIARFISDLQQAERPVILVGG
                     GVRLADAQDDVRALGRRLNVPCFPTWNALDVISSDYENYGGRVGTYGGAGRNFGIQNS
                     DLLLSIGSRISGRITGGNVQSFARQAKKYLVEIDPAMVQRKFQQVPFDVNILCDAKAF
                     TQRVLIALDRRSKPVPDFSAWTGRVMEWKRRYDPVRPEFFAQRERVHPYAFMRRLSEK
                     MGATDVLVGDCGGNIVVSNHAFETKYGQRNLTNNGNSPMGFSFAGAMGAWFADPTRQV
                     VCTIGDGGFNMNPQELQTFVNYGVKVKTFILNNHIYGITKAYQETNFQGRAEACGPKG
                     YHPPDFLKVVQAYGIKTVAIANHAEMDAKIDEVLQFDGPVVCDVDMHEFHTYEPRIFG
                     WKTPIEDMYPYLPREEFRANMVIEPAEGWMSPEYPDVVRRTDQSQP"
     gene            complement(113820..115328)
                     /locus_tag="PK063_00495"
     CDS             complement(113820..115328)
                     /locus_tag="PK063_00495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HMZ95539.1"
                     /translation="MSKPLDVLLVTPPSRVQVYQELSRDFAAIEPPVWSGLIATYLRQ
                     HSCSVAILDAEAQGLTHQQTAEQIAAIAPRLAVFVIYGQQPSASTQCMPAGRKVCEIL
                     NTLADIPTLVMGTHPSALPKRTLLEEPYTYVCQGEGPATILGLVVALRAPQHSLREIP
                     GLWHLEEGHAVGNVPAPLFSNLDRDLPGQAWDLLDMSRYRAHNWHCFGNPEARSPYAS
                     LQTSLGCPFTCSFCCINAPFTTPMLRVWSPDNVIGQIDRLVREYGVSNIKIPDEMFVL
                     NRRHVMGICDRIIERGYRLNIWAYARVDTVQDEVLEKLARAGFTWLGLGIESGSQHVR
                     DGVEKGRFGEREIVATVERIRSHGIHVAANYIFGLPDDTLESMRATLDLALTLNTEWA
                     NFYCAMAYPGSALYGLAKQHHWTLPDDQGGPGWIGYSQHAYECLPLPTDSLTATQVLD
                     FRDRAFQEYFGHPSYLAMLQRTFGSHVVAHVAEMCRHQVRRRHHDQASHQAA"
     gene            complement(115312..>115596)
                     /locus_tag="PK063_00500"
     CDS             complement(115312..>115596)
                     /locus_tag="PK063_00500"
                     /inference="COORDINATES: protein motif:HMM:NF012382.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HMZ95540.1"
                     /translation="HDRITHDGVLQCRRPDAAFYLFVDISRTGLDDMTFCRRLLEEEH
                     TAVTPGRCFGDAYASCIRLAVCGQEEDVLEGVSRTIAFAKKLGGCHVQAA"
     assembly_gap    115597..115696
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<115697..116370)
                     /locus_tag="PK063_00505"
     CDS             complement(<115697..116370)
                     /locus_tag="PK063_00505"
                     /inference="COORDINATES: protein motif:HMM:NF012382.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HMZ95541.1"
                     /translation="MTQQRASMPQFKSRPAFSSRGERLIGQEMFRVLDQAQALERQGH
                     RIYHLELGNPRVAPPSQILEATIGELQAKRVGYAPMGGLQELRSAVVERYASLSGKPI
                     AASQVVISPANMLIHQFLDITCNPGERIVLFTPAFPSYWAAAAHLGLDVVPVPLPARD
                     GFSLSRPSIDAALAAKPRAIIVNSANNPTGAVYEPAILHELVARCGQAGIWLLSDETY
                     ADLTFAG"
     gene            complement(116367..117131)
                     /locus_tag="PK063_00510"
     CDS             complement(116367..117131)
                     /locus_tag="PK063_00510"
                     /inference="COORDINATES: protein motif:HMM:NF012695.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HMZ95542.1"
                     /translation="MAQFADCDVIILCGGFGTRLQSVVSDRPKPMAEIHGRPFVSLLV
                     EHFLRHGARRFIFSTGHFGEMIEDWFLRHRGAYETLFVRDPVPLGTGGALAHAMPLVR
                     SNPFLVLNGDSFCEIDPERLLRFHTRKRAGATIAVTHDESREDTGAVALGEGDRVLSM
                     VEKPRTRTANYHNAGVYLFDRAVTTLFPDMPVWSLERDLLPRLVTHQCYGFVTASPLH
                     DIGTPERLAHFREIWKDTSAYFPTSLLHQTQGSIAR"
     gene            complement(117131..118201)
                     /locus_tag="PK063_00515"
     CDS             complement(117131..118201)
                     /locus_tag="PK063_00515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HMZ95543.1"
                     /translation="MIISRTPFRISFFGGGTDYPVWFREHGGAVLATTIDKYCYISCR
                     QLPPFFEHRTRIAYSRIELVNNNQEIEHPAVRGVLKYLNIDDGLEIHHDGDLPARTGL
                     GSSSSFTVGLLHTLYALQHIMPSKAQLAQAAIHVEQDVLGEAVGCQDQVLAAHGGLCK
                     ATFFQNGDIGHAPIIMRPERLAAFQNHLQLYFTGFSRIASEVAREQIDRTNQRRSELS
                     TMLQMVDEGVSILTGDRDLADFGSMLHEAWMLKRRLTSRITTPAIDAIYAAAREAGAL
                     GGKLLGAGGGGFMLLFARPEDHERIRLALPGLLQVPFKFEGLGTQIVFYQEDQLMLDD
                     VWAQSSAQTAARLKATLIGKAA"
     gene            complement(118232..119179)
                     /locus_tag="PK063_00520"
     CDS             complement(118232..119179)
                     /locus_tag="PK063_00520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HMZ95544.1"
                     /translation="MTTGSTHVLITGGAGYLGSVLTRRLLDRGYAVTVLDNFMYRQNS
                     LMDCCAEEKFQVVRGDCRDERLVTDLLRKADIIIPLAALVGAPLCDRDRVGAYTVNFE
                     AVQLLCKLSSPRQQIIFPVTNSGYGIGQPGVPCTEDSPLRPISLYGETKVKAERVVLD
                     RGNAITLRLATVFGVSPRMRMDLLVNDFVWRAVHDRAVVVFEGHCKRNYIHIRDVVRT
                     FLHAIDHFDDMKNRPYNVGLDDANLSKLELCREIQRVLPQFVSFEAPIGEDPDKRDYI
                     VSNQRLLETGFKPEWSLERGIRELIKCYTVVKAGQYANV"
     gene            complement(119232..120425)
                     /locus_tag="PK063_00525"
     CDS             complement(119232..120425)
                     /locus_tag="PK063_00525"
                     /inference="COORDINATES: protein motif:HMM:NF013227.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HMZ95545.1"
                     /translation="MTLHAHSAKLNPRWCLAQDTIDRQDIDHLIDWLRTYPRLTKGAV
                     TVDFEQRWSQWLGRPYSVHCNSGSSANLLMYYALLRSGKLRNTNVIVPSVGWVTSIAP
                     AIQFGFTPFMCEADPDTFGLDLNHLEDLLKRHHAQTVLLVQVLGVPHRMRELQTLKDR
                     YGFYLLEDACAAIGAEYDGKKVGTFGDMASFSFYFGHQMSTIEGGMVSSSDKELTNLL
                     LMLRSHGWSKDVDQARHQELVGQYQVDDFHSPFVFYEPGFNLRSTDLNAFIGLEQLRK
                     LDWMTGRRQANHDRYLEQLGTRFYTQRPPKGSKVASISFGLLAESPEQRKRIVRALVA
                     EGVETRIFSAGNLGLHPFWMNRYGKASFPVADRVHHCGFFLPNHASMTDQDVLHISRI
                     VLEAA"
     gene            complement(120623..121336)
                     /locus_tag="PK063_00530"
     CDS             complement(120623..121336)
                     /locus_tag="PK063_00530"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar brake protein"
                     /protein_id="HMZ95546.1"
                     /translation="MSDLIVHRHPASFLEVGLSLQLSLPAEGTGAQYGATVLGWKERS
                     WIVCEWPFHFGQPISCAAGTPCLLRYIYNGKMIGYRTDVLHAQLQPFPFLLLAFPATL
                     DEVPLRKHGRVTAQEPIVLLQADQNLRNQPTGSPCRIGGLLTDLSASGCAVLVQRPMQ
                     DFFPGMVIRAEFEIVGTGHVNNLTGVVRNVSMQADGTHLGLEFRFDGKETIEYRGWGG
                     SVRKALESFVLQKHSFESA"
     gene            121543..122793
                     /locus_tag="PK063_00535"
     CDS             121543..122793
                     /locus_tag="PK063_00535"
                     /inference="COORDINATES: protein motif:HMM:NF023299.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3391 domain-containing protein"
                     /protein_id="HMZ95547.1"
                     /translation="MASTKRIPIDQLTVGMFIAGLDQPWYRTPFLLHKWLVSNPDDIV
                     QLKRHGIQIVTIDTDRGLDVGAAPVAAPESTAPVPEPSPASAESVDASTNGHSSHAAA
                     AAATYREAMEAVERVFTDLEAGQPPKIAALKPVVSKLLKQIIEQPEAMMIQFCLDKMR
                     RFDGTLANHGMDVCVLTLILAVENSCTESDMESLGLGALLHDIGFVRLPRNLYRKTSA
                     LTEQEQVLMRQHPQLAATVLSKIDSLPETVSQIIAQHHEFQDGSGFPKLVKSGGLSPL
                     AQLMALADTYDDLVTSRYGRAPLLPHDAIRQLFVLGAKGRYDKNLVEVAIKMLGVYPL
                     GSLIKLNTNECAVVIGLNHEDRLRPRIRIIRGPDGEIQNPPIDSDLQNQAADQPVRTI
                     LRALDPKQEQIDLPQYLDVAVGGA"
     gene            122796..125636
                     /locus_tag="PK063_00540"
     CDS             122796..125636
                     /locus_tag="PK063_00540"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ95548.1"
                     /translation="MSRPSHSRSHHPQPPSGFTPSPEMMGLLWEAVPLGICLLAPDHT
                     IVFANRMAARLLGRSPADCAGKRCSELTGQPLELNDSLHSTGVWKFQSGAAAASDETT
                     DMNATDAPALTVIEWEQLRLSGIPSVSTLLTLRDISRECELEQDRDRLATVAEESPCP
                     IVEIDRNGNILYVNPAMVEVLCRFGYDPNGKPDILPDNLPALVATCLLEGRSLTSQEV
                     VRGEACYSWTLCPVPSNQLVRAYGIDLSEVHATHRALNATADHLRESNRQLDQALQQA
                     QAAARAKSSFLAMITHELRTPMNGVIGMASLLLDTSLTEEQRSFTQTIQQCGEAQLSL
                     INDVLECSKIEAGKLELETLDFQLRTTVEDVLSQFAERAQRKGLEITGLVHAAVPNAL
                     RGDPGRLRQVLTNFVGNAVKFTEQGEVTLQAFLESDTPAGVMIKFEVTDSGIGISEEV
                     QGRLFQAFTQADSSTTRKYGGTGLGLAISKQLVELMGGTVGLRSKPGEGTTFWCTALF
                     QKQAVCSPAIVPSAELSGRRILIVDDNESNRTILHHLVSGWGMHDGQARNATEAMHML
                     EQAAAKGEPYDAAVLDMLMPGKDGLQLAQDIRAHQHGAGVRLVVLTSLIQPGHAERAR
                     RAGFTAYLTKPVRHDQLQGCLRVVFGIQHKAATASTATGKGQPISPTLITRHTLAEQS
                     PRPRILVAEDNVVNQKLAVRMLDRLGYQPDVVSNGQEAVTAFERESYAAIVMDCQMPT
                     MDGYEATRLIRAQEERPDASRTRAHIPIIALTANALPGDRERCKAAGMDDYVTKPVKT
                     DDLGIILQRWAPVKAAAEVAPPAPARDLSKTDARVFDAGAMLANIGGDAELFDQLIRL
                     FLDRHSVMMKEIESAIGQADAAALERAAHSLKGTAGNLCAPDVVLLASQLEASGRLGT
                     LTEAPSLLVRLDRTVQELVAVLSRQINPTDSQ"
     gene            complement(125753..126232)
                     /locus_tag="PK063_00545"
     CDS             complement(125753..126232)
                     /locus_tag="PK063_00545"
                     /inference="COORDINATES: protein motif:HMM:NF014660.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HMZ95549.1"
                     /translation="MKCQSTRFGTFEVNDDTLLVFPSGILGFPDWTKYVMLDHDTDAP
                     FKWLQCVEEPQLAFVILDPALFKPDYQVTITTDALIEIQKQENDEVSIVTILTIPSDD
                     PTAVTANLRGPLVMNHRTRLCKQLVLPEDLPTRYPLFAAASAAPSQSPSQPLQASAR"
     gene            complement(126326..126487)
                     /gene="csrA"
                     /locus_tag="PK063_00550"
                     /pseudo
     CDS             complement(126326..126487)
                     /gene="csrA"
                     /locus_tag="PK063_00550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774971.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
     gene            complement(126562..127452)
                     /gene="flgL"
                     /locus_tag="PK063_00555"
     CDS             complement(126562..127452)
                     /gene="flgL"
                     /locus_tag="PK063_00555"
                     /inference="COORDINATES: protein motif:HMM:TIGR02550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009424 - bacterial-type flagellum hook
                     [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HMZ95550.1"
                     /translation="MRVADQQMYNTLLGNLQRSRLQMLTSQEQVSSQRRVSTPEDDPS
                     SYGQIVLDKSALSQTKQWIRNIDFGTSRVNAADQALGQVQTLITRVRELTIQASSDTT
                     SAEGRQSIAKEVRQLQRQLVQLGNTEVAGQAVFGGTKTNVTPYVITTGDTVTYQGNTE
                     TQSISVGENQTVQILVPGSSIFTGGTTNMFDSLRDLLTALESNNRAGIQTGIGNLDLA
                     TAQISDAQGTVGALANRLQVTHDALDTATLTISKAISDNQDADLATAISQLSLQQVAV
                     QAASQTFSKIFDSSLINYLR"
     gene            complement(127483..128877)
                     /gene="flgK"
                     /locus_tag="PK063_00560"
     CDS             complement(127483..128877)
                     /gene="flgK"
                     /locus_tag="PK063_00560"
                     /inference="COORDINATES: protein motif:HMM:TIGR02492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009424 - bacterial-type flagellum hook
                     [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HMZ95551.1"
                     /translation="MSGLNGLFGVGSNALASFQRAMSVTGQNIANVSTPGYSRQEAVL
                     TETLPENGRPGQIGTGVQVSEIRRSVDSFVEQQLLNSNERIGQFGASQKALSQIQILF
                     NDANDQGIAAGLNEFFKAWQDVATNPADLTARTVLLTKADGLTKVLNQASSQLSTQRI
                     SLDGQIGSAINDINALASKIADLNAQIKLTEVGGQQANDLRDQRGRFLNDLAGLVDIS
                     SIEDGNGQVTVFVGVGQVLVTDHTAFKLTGVPDATNNGLLDVRYDGGTGPNTDITSSI
                     SGGRLKGLLDARDTTATGLQTSLDTLTAQLVSQVNTQHKLGYGLDGSTTQDFFTATGT
                     TAGTISMALTDRQKIAASSTAAGVPGNNVNALALANLQTASVAGLGNTTFQSYYGAMA
                     GSFGATLQGATRDLQGQEILHDQLLAHRAEVSGVSMDEELINMLKYQRAFQAASKLIT
                     TSDEMLQTILSLKR"
     gene            complement(128889..129332)
                     /locus_tag="PK063_00565"
     CDS             complement(128889..129332)
                     /locus_tag="PK063_00565"
                     /inference="COORDINATES: protein motif:HMM:NF016985.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HMZ95552.1"
                     /translation="MSTLSQTTPTESDMLVRGMLDKMLAFQSLLLEEQDAIRSLSFGQ
                     FTSVTTRKSQLLDEIRDFEQRRRQQTSSELSRQDARTTMEAKLLAAIGETDRLNRFNA
                     ALIGQSLEFLQGALKRWQRAPESAALYSSAGTAVPAGAGLVRAKG"
     gene            complement(129408..129713)
                     /gene="flgM"
                     /locus_tag="PK063_00570"
     CDS             complement(129408..129713)
                     /gene="flgM"
                     /locus_tag="PK063_00570"
                     /inference="COORDINATES: protein motif:HMM:TIGR03824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HMZ95553.1"
                     /translation="MEISHNGRAADLAKILLGVQETDRTQNKKNASQTTPSQDRVQIS
                     ERAKELQRLRAAAEQPDHERDARVGQIQQSVEGGTYNVDGKKVADAIIRNVLTDAVL"
     gene            complement(129814..130143)
                     /locus_tag="PK063_00575"
     CDS             complement(129814..130143)
                     /locus_tag="PK063_00575"
                     /inference="COORDINATES: protein motif:HMM:NF021638.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod-binding protein"
                     /protein_id="HMZ95554.1"
                     /translation="MDIKNLLSGQLDLAQMNATQPAGLERVQGLEKAGQKSTEAMHKA
                     GQEFEAYFISYLIGKMRETVPKGLLDRKGEQVWYSFYDQEIAKLATQAGGIGLTAFVD
                     AYVEKNK"
     gene            complement(130161..131471)
                     /locus_tag="PK063_00580"
     CDS             complement(130161..131471)
                     /locus_tag="PK063_00580"
                     /inference="COORDINATES: protein motif:HMM:NF003676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009428 - bacterial-type flagellum basal
                     body, distal rod, P ring [Evidence IEA];
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring protein FlgI"
                     /protein_id="HMZ95555.1"
                     /translation="MTKPRKQQRAMIMQCFRLMLSSGVLRTPSVDPELLARPWTPPPP
                     KPAPVSEPRQQMSPWFRRTAVGMLAFLTISFFSASLAHAVRVKDVATIEGVRENQLIG
                     YGLVVGLDRTGDQVIGGQFTIQAMMSMLNKMGINLVIDPIQLLTRNIASVMVTAKLPP
                     FVKPGMTLDAIVSSMANAKSLQGGTLLLTPLKAPNQQVFAVAQGPVSIGGFLGGTGGA
                     GGATVTKNHQAAGVVPAGAIVEKELVVDIDQWDTVSVLLRHPDFTTAIRTAEAIDGTF
                     GKGTAVPVNAGLVKTTLPSTFQGRVVEYIATMEGLDVSVDVAAKVVVNERTGTVVLGE
                     HVRLSTCAISHGNLTISVKNTLNVSQPPAPLIGSTQGQTTVTPDVQTDVAEEQSRLIV
                     VDQTVTLGEVVRALNAVGVTPRDLVAILSALRAAGALQANLEIV"
     gene            complement(131514..132098)
                     /locus_tag="PK063_00585"
     CDS             complement(131514..132098)
                     /locus_tag="PK063_00585"
                     /inference="COORDINATES: protein motif:HMM:NF014195.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009427 - bacterial-type flagellum basal
                     body, distal rod, L ring [Evidence IEA];
                     GO_function: GO:0003774 - cytoskeletal motor activity
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body L-ring protein FlgH"
                     /protein_id="HMZ95556.1"
                     /translation="MPPPKTTGSLWQEENGRAYLYEDLRAMRAGDIITILISEKHKGS
                     KSADTSAEKDSTVSNGLGGTGMGYLGLPGIRLGGEAKRGFGIDASAKNKFGGKGATNR
                     EDTLTGTISAIVTEVLPNGDLRIEGRREVTVNSERQIMTIAGIVRRVDVNTKNTVQSS
                     AIADAKIEYSGLGVVDDVQRPGWFVRILDWVYPF"
     gene            complement(132217..132990)
                     /gene="flgA"
                     /locus_tag="PK063_00590"
     CDS             complement(132217..132990)
                     /gene="flgA"
                     /locus_tag="PK063_00590"
                     /inference="COORDINATES: protein motif:HMM:TIGR03170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009428 - bacterial-type flagellum basal
                     body, distal rod, P ring [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring formation chaperone
                     FlgA"
                     /protein_id="HMZ95557.1"
                     /translation="MATISLLASAVLPAMAGERAPIRPLFRVHEALVQGAHSLPLARG
                     KHTIYPEQIRGVIRDFVKRELAGRAVDCQVALGDPQQPIVVPSGTMDLQVSANHSEEP
                     LGRRVFQIHLTVNGRFIKTVEATADVAAIVEVVVPVRSIKVDEEIAADDVATERLVLY
                     DLKQPFAMNPSDVVGKAAIRPLPPQNAIRLTSLRRPFAVHKGDRVTIEARQGGLSIQT
                     VGVTKSHGELGQTITVSNVDSGKDLRATVVGPGVVRVSF"
     gene            complement(133048..133839)
                     /gene="flgG"
                     /locus_tag="PK063_00595"
     CDS             complement(133048..133839)
                     /gene="flgG"
                     /locus_tag="PK063_00595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009426 - bacterial-type flagellum basal
                     body, distal rod [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgG"
                     /protein_id="HMZ95558.1"
                     /translation="MIRAMWTAATGMTAQQLNVDTIANNLANVNTNAFKRSRAEFGDL
                     LYQIQRLPGTNASNVGVFPVGVQVGGGVRPITVAKEWMQGNMRQTSNDLDLAIDGAGF
                     FQVARPDGTIMYTRNGSFKRDNVGNLVTGDGDQLTPVITIPSGALKIDIGQDGTVSVL
                     LPGVTQASQVGQIQLVRFDNPSGLVAMGGNLFLDSFASGPAQQGTGGFSTGFGTLQQG
                     FLESSNVNLAEEMVNMIIAQRSYEINSKTIQASDEMMQIANNLRR"
     gene            complement(133850..134617)
                     /gene="flgF"
                     /locus_tag="PK063_00600"
     CDS             complement(133850..134617)
                     /gene="flgF"
                     /locus_tag="PK063_00600"
                     /inference="COORDINATES: protein motif:HMM:TIGR02490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgF"
                     /protein_id="HMZ95559.1"
                     /translation="MNRAIYPILSGAVAQEKQLQVFANNLANVNTAGFKQDQQGFRGL
                     LARGGSVGMGAASSGITSTISTRPAGPTERVFTEANGMRTTFEPGRIRITGNPLDLAI
                     QTDGFFEVKTPDGVRYTRNGIFSLDGQRRLVTNLGHPVMGTKGEIKVPPGNIQINAEG
                     GIQVDGNAIGTIKVVEFPPNEMPQKFAEGLFTGGKPSVSKKPQLQSGHIEESNVNSLS
                     EMVKMIQGMRSYESAQKLIQTLDHMTDTAIQDLGRVQ"
     gene            complement(134896..135765)
                     /locus_tag="PK063_00605"
     CDS             complement(134896..135765)
                     /locus_tag="PK063_00605"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: protein motif:HMM:TIGR00254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HMZ95560.1"
                     /translation="MSVPPSVTGESSAAVEPEPDHHHAWSDNDALTRSYDAARFGVLA
                     CLLFMAGGLYWTAAIGLLTISALTAYPVMVSIGVAFTLMIFGATFWTPRSRSSAVRPL
                     WSAAESGSKTTYDPVTGLPLNRLFLSLLNQALIRGQKHGRQVAVLIIELDYFTPAAES
                     PAELNRHLMYRIEAARVKSALRTTDTVARIAERTFAVLVDQITDADNLLLLARKMQGA
                     IALPITLDHHEVFLTGRIGLALSKRDDLDPNALLEAAARALEMARTDASGMSGIETAL
                     PQPQTDSTSTIAA"
     gene            complement(135926..136687)
                     /locus_tag="PK063_00610"
     CDS             complement(135926..136687)
                     /locus_tag="PK063_00610"
                     /inference="COORDINATES: protein motif:HMM:NF005413.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliA/WhiG family RNA polymerase sigma factor"
                     /protein_id="HMZ95561.1"
                     /translation="MMEARKMSATGNASRRVIAEADRERVIQEFTHVVKAMAHRLAFR
                     LPAYMDAEDLMSVGIMGLMDAMDKYDPTREAKFKTYAEFRIRGAMLDEIRSMDWIPRS
                     VHERISLLQKTYSELLHRFGRPPTDQEVGKELKMSADELDEFLTRSRGAVVISLDDLG
                     VQDADGHKIISMLTDSNQPDPLSVLVNERARHVLEAAIQDLPEKERLVLSLYYFEELT
                     MKEIGQALKVTESRVCQIHSKAILHLKARLEPVDV"
     gene            complement(136707..137573)
                     /locus_tag="PK063_00615"
     CDS             complement(136707..137573)
                     /locus_tag="PK063_00615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HMZ95562.1"
                     /translation="MAIEPDILDPQLNTFDGSVGPSRTQVITVTSGKGGVGKTNVVAN
                     TAIALAQTGKRVLVLDADLGLGNVDILLGLTPKYTLEHVLAKTCRLEEIALTGPNGIV
                     VLPASTGISQLTVLTEAQQLILQEELERLASTMDVLLIDTGAGISSTVTYFAAAAQSI
                     VVVVSPEPTSLTDAYALMKVLLRQYRERRFHVLVNMVKSPRDAARIYRKLEVAVSRFL
                     HISLDYLGAIPQDDYVPMAVSQQRAVIDLFPHAPASRAFRELTEAVAQLTPPALPKGT
                     VQFLWQQLLRTH"
     gene            complement(137601..138884)
                     /gene="flhF"
                     /locus_tag="PK063_00620"
     CDS             complement(137601..138884)
                     /gene="flhF"
                     /locus_tag="PK063_00620"
                     /inference="COORDINATES: protein motif:HMM:TIGR03499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0044781 - bacterial-type flagellum
                     organization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HMZ95563.1"
                     /translation="MKVRTFHVASMHEAIRSIKDTLGPDAVILSTKRVRSWDNGFGLL
                     GGSMLEVMAAIEDDAAVPESAPILGEDERSAPAVAQAPAVPAEESRFQKTLQGAIEKR
                     EDQPRPASRQASFVPQELSRTAKSSPVTKDGQGTTFQSFQRVYEDLLAQGVEHATAEA
                     CLRELRETLVEQGTSQRNSSLQLLRTVLLDRVSTAGPLLSNAGEQKIAMFVGPSGVGK
                     TSTIAKLATHYGIVEQRSVALITMDTYRPAAVEHLRLYAEVLGIELAVASSCEDARAA
                     IAQAREAELILIDTAGFNPYEPIAAQRWRGLLNGALPLEVHLVLAAGTRVPDIVVSTS
                     QCVDVPSLRLLFTKLDETTGYGGIFEATHRTGIPLSYWGTGQRVPDDLVQAQVNRLGD
                     LLLGGQVRTPGEQNGQPWIRQAAPAVVPGIKTYTR"
     gene            complement(138881..140989)
                     /gene="flhA"
                     /locus_tag="PK063_00625"
     CDS             complement(138881..140989)
                     /gene="flhA"
                     /locus_tag="PK063_00625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HMZ95564.1"
                     /translation="MAKDNTSIPSTSLVKHPDILMSVGVVGILMVMLVPLPRFFLDLL
                     LSFNITLSIIILLVGMQVRRPLEFSVFPSILLMVTLLRLALNIASTRLILLHGNEGAA
                     AAGEVIRAFGNFVVGGNYTVGLVVFTILVIINFVVITKGAGRVAEVAARFTLDAMPGK
                     QMAIDADLNAGLINDKEARQRRKEIAQEADFYGAMDGSSKFVRGDAVAAVVITLVNIL
                     GGLTIGVLQQGMTVAAAAQTYTLLTVGEGLVAQVPALIVSTAAGIVITRAASEVNLGF
                     EITRQVLISPKAIGTASGILLAMGLVPGLPHLAFLALGSLTGWMAFQLNEHQKTAVAT
                     PEPESPQVKAEEAATQVVPLDLMEVQVGYGLIGLVDGGQGGALLDRIKGLRRQFAEQM
                     GFVLPPIHIRDNLQLRPNEYAALLKGVELAKSEVMPAHVLAIDPGTAQRGIIHGLPTK
                     EPAFGLPALWVPEQQREQAQMAGYTVVDPGSAIATHLSELIKRHAHELLGRQEVQGLL
                     DQLGKNHPKLVEEVVPNLIPLGTLVRVLSHLLREGVPIRDLRTILETLADHAASTKDA
                     DILTEVARQALGRTITKQYLAPDGSLPIIGLDPRLDRTLADQANAVGQGNQWIPDPMV
                     AQKLLSALKQAAERMVGRGHQPVILCSPSLRRHLRKLTDRILHSVPILGLNEVDSVTR
                     LQAMETVRLDLDGGDTRSLA"
     gene            complement(141010..142092)
                     /gene="flhB"
                     /locus_tag="PK063_00630"
     CDS             complement(141010..142092)
                     /gene="flhB"
                     /locus_tag="PK063_00630"
                     /inference="COORDINATES: protein motif:HMM:TIGR00328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhB"
                     /protein_id="HMZ95565.1"
                     /translation="MADSAQNRTEQATPKRKAEARSKGQIALSRDAAMAVALLGSFAA
                     LYWMTPGIMERLRHSLQRWLSQSMEDSTLRALSLDHLHLILRQIGIDVFVMLGPVVAG
                     IAVVGVGANLMQTGFLWRKDGLSIDWSRISPVGGFSRLFSVRALSELVKSWLKILAIG
                     SVGYLTIKEDMLQFLPLTQFGMETLLPTVGWATFKAALMMSGAALVIGALDYGYQRFE
                     WERGLRMSRDEIKEESRAAEGDPGLKAKIRSTQREMSRKRMMAAVPTADVIITNPTHL
                     AVALKYDSKAMGAPIVVAKGAGFIAEKIREIGRQHGVMIVENKLVARTLYKLVEVGRE
                     VPEDLYRAVAEILAFVYRVRGKLPPA"
     gene            complement(142085..142873)
                     /gene="fliR"
                     /locus_tag="PK063_00635"
     CDS             complement(142085..142873)
                     /gene="fliR"
                     /locus_tag="PK063_00635"
                     /inference="COORDINATES: protein motif:HMM:TIGR01400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0044780 - bacterial-type flagellum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthetic protein FliR"
                     /protein_id="HMZ95566.1"
                     /translation="MNVAQTLHLALPQFQSFSILLVRIAGIISVFPILNTLTIPMPVK
                     AGLVTMLGLVLAPIIQLPSFPNDPALVVAGIGSEFLIGLTIGLAVRLLFSGFQVAGEL
                     VGTQMGFSAIQMFDPMSHQNAPIIAQFQLTLGSLVFLSLNAHLMVVHAIGMSYEFVPP
                     FGAKLSDSIATDIIHLAQNMLGVALKMAAPVFATLLIVNTVLAILGRAVPQMNVFVLS
                     FPITIGAGLFAMSLAMPFTLSLFEKEFENLVETILSLLKGLGHG"
     gene            complement(142889..143158)
                     /gene="fliQ"
                     /locus_tag="PK063_00640"
     CDS             complement(142889..143158)
                     /gene="fliQ"
                     /locus_tag="PK063_00640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HMZ95567.1"
                     /translation="MTIETVTEIGRQAIETAMLVSAPVLGLSLVVGLMVSTFQAMTQI
                     NEATLTFVPKVLAVFAATLLFLPWMMGVLIAFMTHIITSIPTLIH"
     gene            complement(143170..143970)
                     /gene="fliP"
                     /locus_tag="PK063_00645"
     CDS             complement(143170..143970)
                     /gene="fliP"
                     /locus_tag="PK063_00645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014960008.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HMZ95568.1"
                     /translation="MPDDNLTSLQQAKKGGAGTVPRCMGWVGLVLLVVLAGASSVHAE
                     GPSLTLDLGQSGTKQTAVVLQILALLTVLSLAPALFIMVTSFTRMVIVLSFLRQALGT
                     QQVPPNQVLISLALFLTMFVMAPVGQAVYKDALQPLLAEQIGYEDAWNRGIQPIRGFM
                     LKQMRDKDLELFLELSHSPKPAQVDQVPTHVIIPAFVLSELRISFQIGFLLYIPFLIV
                     DMVVASVLMSMGMMLLPPVMISLPFKLILFVLADGWYLVVGSMVKSFQ"
     gene            complement(143957..144325)
                     /locus_tag="PK063_00650"
     CDS             complement(143957..144325)
                     /locus_tag="PK063_00650"
                     /inference="COORDINATES: protein motif:HMM:NF016250.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthetic protein FliO"
                     /protein_id="HMZ95569.1"
                     /translation="MEIWESVVRMVSALGIVLALILGLLAIVKSRVGQRFLPVGGAPL
                     IKVLGSSSLGARKQVMLVAVAGEVLILGTTPTDLVSLGKVTDPEQVKRLLLEASSNMA
                     LSPAQAVGSEYREETLHAGR"
     gene            complement(144382..144750)
                     /gene="fliN"
                     /locus_tag="PK063_00655"
     CDS             complement(144382..144750)
                     /gene="fliN"
                     /locus_tag="PK063_00655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_function: GO:0003774 - cytoskeletal motor activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliN"
                     /protein_id="HMZ95570.1"
                     /translation="MGNGDTTPQADASSGADMSPQATSFPPVDNQGAVPANKNIDFVL
                     DIPLQVTVQIGSTRMLIRELLQLGQGSVIELNKLAGEPMEVLVNNKLVARGEVVVVNE
                     KFGIRLTDVVSPNQRIQQLG"
     gene            complement(144780..145751)
                     /gene="fliM"
                     /locus_tag="PK063_00660"
     CDS             complement(144780..145751)
                     /gene="fliM"
                     /locus_tag="PK063_00660"
                     /inference="COORDINATES: protein motif:HMM:TIGR01397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliM"
                     /protein_id="HMZ95571.1"
                     /translation="MDKILSQEEIDALMGGVMSGEVETAPKEEEEPGGIKTYSLTSQE
                     RIIRGRMPTMEMINDRFTRQQSVSWTSVLREKIEFSVLGTQIIKFGDFIQKVPVPSSF
                     NLFAMEPLRGNGLYIMDAMLVYLIVDFFFGGKVQTHVKPEGREFTTIQLRLIKKLVQQ
                     ALVDLEKAWQAVMPVKLNYLRSESNPQFAMVVTTSEIVVVVTLQVHLGDITREMFIAY
                     PYSMLEPIKEKLYSGLFADNVEQDSSWGSRFKDSLQECDVAVTVQLGTAKINVEDLMN
                     FSPGDVLMLDQHPGDPMLCLVEGDPKFHGQPGVFKGNHACRVTKVLS"
     gene            complement(145773..146312)
                     /locus_tag="PK063_00665"
     CDS             complement(145773..146312)
                     /locus_tag="PK063_00665"
                     /inference="COORDINATES: protein motif:HMM:NF015693.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HMZ95572.1"
                     /translation="MSEAAEEKAPAAPAGIPMKMVIIIVGGVLILALGGAFAMMKMMG
                     GSSAEKTQAEGGGEKAAAHGAAEEKSGGEHGAVADASAIADLDPFIVNLADSPEIRYL
                     KVTMKVEADNAGTVEQIKARTPQIRDAILVLLTSLDSATARSPQGKHKLRDDITERIN
                     GLLPKKSVKSTYFTEFVIQ"
     gene            complement(146645..147868)
                     /locus_tag="PK063_00670"
     CDS             complement(146645..147868)
                     /locus_tag="PK063_00670"
                     /inference="COORDINATES: protein motif:HMM:TIGR03506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook protein FlgE"
                     /protein_id="HMZ95573.1"
                     /translation="MGILTSMFTAVTGLSSYGNAMGVIGNNIANVGTAGFKSSRATFS
                     DLISSSMAGGAGSDQIGLGVYLNDVQTNFSQGSMTTTGNTFDLAIDGNGFYLVRNASG
                     SNFYTRAGQFKVDSVGQVVDASGALLQGYQADTLGNITSTIGGITLTSSAVPPQSTST
                     ATILGNLNANATAPTAAFATTDTTSYNFSTGMTFYDSLGNSHQMQLYFRKTAANAWGV
                     YSQIDGGAATAQTNMTFNASGAVTAGGTQTITAALTNGATTPQSISVNLASLTQFGAA
                     SGVQSQTQNGYSSGTLDRISVDKEGKVMAQFTNGQTRALAQVVLSRFTNPDGLANVGD
                     NHFLETVESGAALAGAPTINGLGRVLSGTVEQSNVDLGKEFVDMIITQRAFQANSRAI
                     TTSDEMLQELVNLKR"
     gene            complement(147942..148232)
                     /locus_tag="PK063_00675"
     CDS             complement(147942..148232)
                     /locus_tag="PK063_00675"
                     /inference="COORDINATES: protein motif:HMM:NF015896.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook capping FlgD N-terminal
                     domain-containing protein"
                     /protein_id="HMZ95574.1"
                     /translation="MDISKVITQTPAADPSTPTTEGPKPLGKDDFLKLLVTQLQHQDP
                     LKPMENEAFIAQTAQFSQLDQMTKMVSLMEKSVALQESAQNKTTQTGTTAVA"
     gene            complement(148244..149839)
                     /locus_tag="PK063_00680"
     CDS             complement(148244..149839)
                     /locus_tag="PK063_00680"
                     /inference="COORDINATES: protein motif:HMM:NF014207.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HMZ95575.1"
                     /translation="MATDMQPVFNGFPSRSSQGIQDARDRQPAVHGSDPSRNFESVLG
                     RAEARQTPPKHEAPTPRSGEKAGLHARQVSRSISDSSSQPSERSSVAPSDDHSSNRCE
                     CAGEKAQPSTDKSEEKSTTKESKKKDPGQDAVSQDMLLASMMVPTAQAAPPEQQTPQA
                     EAQSDSHSETSVNAAAAISSDRAEDGSASVTTLVAATSEAGAGTQEVLAGQSDPKADA
                     GKDAAQAKERAENGNEMVQTTAKELPSLAGDNSSPDARVEDRTDSTAAARTDADRMNP
                     AIAAMTSSKQNPHMAEQGPSEGADRSAILDALAQGASLSEGQAGSSTGRFLEPDGQNL
                     SDSSGGTDRSLPNQVPSVEQNARPAFMDRINDVHQSTPSVNDSSSGRSESGQTTAVLR
                     ASESERVGELRGMAPVSQSVTLDLDPLDMGPLRVRVMMSDQTVHAHIRTEHGELGQGL
                     LQQGQSLESSLRTSGLEMGMLRVTVDQQQGRGDNAWMFQQQQQQQNRPSSPGLSQTVA
                     REDERGARGERGAGSNERVSFFA"
     gene            complement(150036..150668)
                     /locus_tag="PK063_00685"
     CDS             complement(150036..150668)
                     /locus_tag="PK063_00685"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95576.1"
                     /translation="MMETGSRSEQGRCVGVVALIAFGAVFLTLITTAHATEEVKPAAV
                     PQKEETKPESVKKDVQGPATSAPREIYEMLEQRKRLLDKRETAVRGSETHLLELKAEL
                     EQIVTRHEQAVEAEKKRRQAAQAKGAGEAEKAKTTAKATPAVNVNQAQLAKIYEAMPA
                     EEAAARLERMPERKALEVLRLLKGKSAGAILAEVKPERAARLTEQLLTTP"
     gene            complement(150665..151105)
                     /locus_tag="PK063_00690"
     CDS             complement(150665..151105)
                     /locus_tag="PK063_00690"
                     /inference="COORDINATES: protein motif:HMM:NF014144.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009288 - bacterial-type flagellum
                     [Evidence IEA];
                     GO_process: GO:0071973 - bacterial-type
                     flagellum-dependent cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FliJ family protein"
                     /protein_id="HMZ95577.1"
                     /translation="MNVTVLRAYAVQLEEVAKLELAELSHALQQTVNRMAMLESRAKE
                     DADRYLHQVRAGSTVDQVYGHLDAMDQAIAARKGLEQALATEQARMEQKRAELLEAMQ
                     YRKKLDLLDARAALEIRRRRERQDQQLLDERAWRRSPLHKGERA"
     gene            complement(151102..152415)
                     /locus_tag="PK063_00695"
     CDS             complement(151102..152415)
                     /locus_tag="PK063_00695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliI/YscN family ATPase"
                     /protein_id="HMZ95578.1"
                     /translation="MPVKLSARLEHVEPLSVTGRVAQAVGIVIEASGPFTSVGEVCEI
                     TREGGHGSVMAEVVGFREDRVLLMPLGEMQGIGPGSRVVMKGHVASVPVGPQMLGRIF
                     DGLGHPLDGLPALRSDVRVPLYAPPLNPLHRARITQPVDLGIRAINALLTCGQGQKIG
                     VFAGSGVGKSVLLGMISRYTQADVRVIALVGERGREVKEFLERDLTPEARARSIVVVA
                     TSDQPPLVRIRGALVATAIAEYFRDCGKHVLLMMDSLSRLAYSQREVGLAIGEPPTTK
                     GYTPSVFAVLPKLLERVGPAQSGGSITGLYTVLVDGDDLNDPVADAVRSILDGHIVLS
                     RELAARNHFPAIDILQSTSRVMRDIVTPAHYAAARLVLERTALYRRSEDLITLGAYKP
                     GTSKDLDKAVSAHDGITAFLRQETKQAVGLPQSIDALLALAGTIQ"
     gene            complement(152399..153448)
                     /locus_tag="PK063_00700"
     CDS             complement(152399..153448)
                     /locus_tag="PK063_00700"
                     /inference="COORDINATES: protein motif:HMM:NF014196.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ95579.1"
                     /translation="MGSAAAGTGVSMAASPESEKELSPRAVLIVDDEPSICLLLAEML
                     ESTGHPVLTAGSVPEALSHLRTRSVAVVIVDVQLGGADGIAFLQQALDIDNRLLGIVM
                     TGHGNIELAVRAMKSGAADFLTKPFQVELVRLAVSRLLELYRLRQENTVLTRTLIRSG
                     NIQLRPVPLADFSRGNRPFGTEDLTEFERGVAEGEKRSTERVAAARQREQSLVASLMT
                     RLEETWQSLHETVEEEIASLSFMIAHKVVRDVVTEKRDLIVTQVRTALAHLHESGLVR
                     VRVHPSDLTVLESARTALSQTPHGLLTLKFETDPSISPGGCLVQAQSLLIDATLDTQL
                     LRLGEALRKRDAGEA"
     gene            complement(153449..154450)
                     /gene="fliG"
                     /locus_tag="PK063_00705"
     CDS             complement(153449..154450)
                     /gene="fliG"
                     /locus_tag="PK063_00705"
                     /inference="COORDINATES: protein motif:HMM:TIGR00207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009433 - bacterial-type flagellum basal
                     body, C ring [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HMZ95580.1"
                     /translation="MAINKELSGAQKAAILLRAIGEEAAAAVMKSLDPKDIRKLGEFM
                     KETANITKQEEDSVIAEFEQASSSGEVQFEGREFMEAILKKALGPEKAARMMESLNTK
                     TYPGIDALKWVDARTVAQILKIEHPQTIAVCLGQMEAEQASAVLALLPVHLHADVSLR
                     LATMQEVQPEVLAELSDSLQEILSASMGMSSMSVGGAELMADILTRVDKNTEGAIMAK
                     ITERDQALAESIRALMFVFDDLVDLDSRGMQELMKEISKEDLPIALRGATPEIKDKFL
                     KNMSSRAAEMLKEDMETRGPVKVSDVEKSQQNILKVCRKLEEEGRIVIGGGGGEELL"
     gene            complement(154456..156015)
                     /gene="fliF"
                     /locus_tag="PK063_00710"
     CDS             complement(154456..156015)
                     /gene="fliF"
                     /locus_tag="PK063_00710"
                     /inference="COORDINATES: protein motif:HMM:TIGR00206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009431 - bacterial-type flagellum basal
                     body, MS ring [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body MS-ring/collar protein
                     FliF"
                     /protein_id="HMZ95581.1"
                     /translation="MFSKFSQFTINQRFIILLALAGSIAGLVAVTLWTQQPDMQVLFA
                     NLATDDAAGIIDKLKDAKVPYETTNGGTTILVPNAQVHDLRLEMAGQGLPHGGGVGYE
                     IFDRTTMGMSDFVQKLNYRRALQGELARTITQMPEVERARVHLAIPERRLFATEQDRA
                     RASVVVSLRPNQNLSKAQIQGIVHLVSSSVEGLQARDVTVVDGHGNLLSNSSSDESAG
                     LSGTQMEYQRTLEKDIETRIQTMLERIVGVNKAVVRVSSVLDFRKIETTEERYDPNGQ
                     VVRSEQRGQEKSSGVNGTTGGVPGVESNVPGGAEGEGGQTSSNNNQTKNETVNYEISR
                     TVSRIVEPTGTIKKLSVAVLVDGTYEGGGKAAEGAAEQPKKYVPRSEEEMKRIEEIVK
                     KAMGYSTERQDQVEVVSIQFGLGVEEPVGAGVEAAADSTRAWMPYIRYAVGGLLFFLI
                     LFMVVRPLMVMLVQSAPVEAVGETPALPASVGQVEAAISGKQPGQILDMAKNNPANTA
                     VVVKQWLKSNA"
     gene            complement(156063..156374)
                     /gene="fliE"
                     /locus_tag="PK063_00715"
     CDS             complement(156063..156374)
                     /gene="fliE"
                     /locus_tag="PK063_00715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HMZ95582.1"
                     /translation="MSDLHIAGANLIKPIEAPGLQQAGQTGEAGGANFLGSLKEAIGH
                     INDAQAGASQAVESLVTGQNTNIHQTMVALQQADASFQLMMQVRNKLVTAYEEIQRMQ
                     I"
     gene            complement(156377..156826)
                     /gene="flgC"
                     /locus_tag="PK063_00720"
     CDS             complement(156377..156826)
                     /gene="flgC"
                     /locus_tag="PK063_00720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009425 - bacterial-type flagellum basal
                     body [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HMZ95583.1"
                     /translation="MDLSDSLAVSVSALDAQRHRLNVIASNLANAQSTKTSTGGPYRR
                     RDVVFQAAPVSSAFQKAFTQVSKGSGRHALDGVKVARVIEDQKPGQTVYDPRHPDADK
                     KGFVTMPNVNVMEEMVNMIGASRAYEANVQAVNATRTMWNRALEIGR"
     gene            complement(156888..157295)
                     /gene="flgB"
                     /locus_tag="PK063_00725"
     CDS             complement(156888..157295)
                     /gene="flgB"
                     /locus_tag="PK063_00725"
                     /inference="COORDINATES: protein motif:HMM:TIGR01396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009429 - bacterial-type flagellum basal
                     body, proximal rod [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0001539 - cilium or flagellum-dependent
                     cell motility [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HMZ95584.1"
                     /translation="MTIFDRTMQLLERSLDLRGARQQVIAANIANEETPKYRATDLNF
                     GQALANAQQGKLPIALVSTHQQHIGPKGSGFQRVQGRIEEVPAGDLPLDANSVNIELE
                     MAKMSDNAQQYNTSASIISMRFKTLLSAIREGR"
     gene            complement(157466..158884)
                     /locus_tag="PK063_00730"
     CDS             complement(157466..158884)
                     /locus_tag="PK063_00730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ95585.1"
                     /translation="MSAQPALQGPSASADEARMVLIVDDEPSMRTALSETVRRMGYQV
                     RSAIDGADAIEQVERLKPWLVVTDLKMPRLNGLELVKALKQKAPQTFIILMTAYGTVE
                     TAVEAMKYGANDYILKPFSTDLLERVILNLQASAEPDEQDAPAALEARAILTQDPGMI
                     RLLTTLEGVAASQATVLISGESGTGKELLARYIHARSPRAHRPFVALNCAALPDSLLE
                     SELFGHERGAFTGAIQKKLGKFEMAHTGTLFLDEISEMNLGLQSKLLRVLQEREVDRI
                     GGRDPVPVNIRVIATTNRSLYHEVTQGRFREDLFYRLNVFPVTVPPLRERPGDIPLLA
                     RHFLRSSAQRNGLTVPTLSERAIADLQQRAWKGNVRELENVMERAILVTTGNAVDVDH
                     LMPGDGTVPIQPVETVETLVAPSAHGSLWEMERDLIFKTLARVKENRTHAAKELGISI
                     RTLRNKLREYRDLGYQVEAEKP"
     gene            complement(158881..160170)
                     /locus_tag="PK063_00735"
     CDS             complement(158881..160170)
                     /locus_tag="PK063_00735"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ95586.1"
                     /translation="MIRQEGDTTNNDLLTRAFRDFDQAATVLQQSYDALTTRLQQMDL
                     ELAQTNASLREHLRETEEMRAHVTAVLESLDTGVIVADSQDVVVRCNHSTEQLLGVPQ
                     AQLRGRQASALLAEIRKDHGEYPLVLPSGVTIALSQTDLTDESGNPIGKLVLIHDVTR
                     IRQLEDRLQRRNRLEAMGQMVGSIAHEIRNPLGSVELFASMLRKDLRDQPQLRSYAEH
                     ISMAVQSMDQLLSNLLVYTRPDCSRLGWHDTEVLIREVLTLASHAIPPDTVDVRCQMH
                     PLVPQLWCDGPKMKQVLLNLVLNAVQAMPKGGTLTLTACPSPPEIQEVPAVHITVSDT
                     GTGIPAELQSRVFDPFFTTKDQGTGLGLAIVHALVEAHHGRIDVESRPGHGTSFVITL
                     PRGPRQPSSTPVSLVTVSAPSERSRHITSITEEKRYE"
     gene            complement(160167..162224)
                     /locus_tag="PK063_00740"
     CDS             complement(160167..162224)
                     /locus_tag="PK063_00740"
                     /inference="COORDINATES: protein motif:HMM:NF024824.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ95587.1"
                     /translation="MRQELPAMMAEPSELVRGALPDPGPRFERLPEIPEWKQFEQGVG
                     LYHQGQYLEARLHFTNMLRDRRESPLRSSIQAFLAESTLQSHDPGVRPLDIIDQYKTL
                     MRENPQSTNAKRAAWRIGDVYRIEGWFQEAQIAYQHALSLSEIDSFDANRAMLGLAYV
                     QRGFKNWKESTQTFDHVLKRTVDPTLLVSASLGEAHSLYRLGRMKDADALYESISGRW
                     PAALRSDAFALLRYADTAGEAKRGPVMREQLLHFYNLYPNRPETPFVLTYLADSYKEA
                     GRWAESSIFYAALLSQYPEAPVAATARLRYADVQEHLDPEGEEINLRHTISAHLDHVP
                     LKAGEMLSPRRLFEQSAKDNEGSIVGSEALFHLGETLERAGKPEGAVRAYEQVVLRSG
                     KFDNDPWPEKGGVQLVRFLRPRLEAALKAEDDFELINIFHRHGPFADRLYAGTELLLK
                     IAEAHRRLGFPVESARLFQSLVRDAKAEKFHEAALMGLAYSYMEQKDMRAARSVFERY
                     RLEFPTGRFSGEALRGILNSFEGEGNLAALLKLGKQWLAHNPRHHDRTMVQLKLAAAL
                     AQSKQPAEAAAIYDGLIKAGQELPAADLLRHAEVLARLNRRSQALAMYKEAVVAGLEL
                     EQEAWAQLQMVQLARGEKREDFAKNGLRALSVNPDSLVRRMAAMLDNELPEPPVDKRG
                     KKP"
     gene            complement(162501..163916)
                     /locus_tag="PK063_00745"
     CDS             complement(162501..163916)
                     /locus_tag="PK063_00745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ95588.1"
                     /translation="MSQSHILVIDDDPAVRQLLAETLTSEGHQVTVMSSGLDGVEAVK
                     DQPVHVVLTDLQMPGIDGLETIDRISKIDSKVIAIVMTGYGTVDYAVRAMKAGAFDFI
                     TKPFEPDTVAVVVRKALDVYKLKQENHLLRKAVRDQYRLEHLVGTSAPMRMVLDFVEK
                     VADSDSTVLIEGESGTGKELIARMLHFNSMRRDRPLVPVNCGAIPETLLESELFGHEK
                     GAFTGAAHTRLGRFELAHGGTIFLDEVGEMSLPLQVKLLRVLQERCFERVGGTRTINV
                     DVRIIAATNQDLAQAVQERRFRQDLYYRLHVIPIHIPPLRERRSDIPLLVNHFIAQFN
                     QLRRTEILGMEPDALVRMTEEEWPGNIRELENMIERLCVLKKRGMITLADLPERALKT
                     AGGKAVEAPEQFIRFSEDGINLTKELEHYENRLIGEALRKANGITSRAAQLLQVNRTT
                     LVEKLKRKGFDPKSHGYSIQN"
     gene            164210..164285
                     /locus_tag="PK063_00750"
     tRNA            164210..164285
                     /locus_tag="PK063_00750"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:164243..164245,aa:Thr,seq:tgt)
BASE COUNT        33741 a        46997 c        47322 g        36035 t
ORIGIN      
        1 cccttgtccg tgaaccgttc gaacatcccg cctccttatg gtgatggggt ctgtaagaga
       61 agccttagct gagtgaatcg atgcaggtca aaggctcgaa aatacttgat gatgtgattc
      121 taactaccgc aatttggggt gtcaaggtat tgagcgaatc gcaaacgacg cgctgcgact
      181 ggtgaagcgc gtgtatttac gatgcgcaga tgcgaggcca agccgcacgc cggtttgaca
      241 gtaaaagaat catcccgata caatcccgca cctttcaacc ggctcctcac ctcagcgcga
      301 cgcggtctta cgtatgaaaa gcaaaagcat cggcattctg acgaaaccca aatttcctga
      361 agtgaaggcc acggtgcagg ccgtggtgag ttggttgcgc tcgcgaaaca tcgacgtgct
      421 cctggatacg acgtcgacaa cattgcttgg agaacaaggc gggtttcaga aaactcaatt
      481 agccagtaag gccgatgtgt tgctggttct gggtggcgac ggcacgatgc tgaatgctgc
      541 gcgcctggcc ggcgaacgcg ggatacccat tctcggagtc aatatgggtg gcctcggatt
      601 tttgaccgaa gtcgtgctgg agaatttgta tccgtctctc gagcgcgtgt tcgccaatga
      661 tttcgtgctc gatgaaaggt tgatgctgag gacccatgtc catcggcacg gcgaaacggt
      721 ggcgcgaggg gtcgtcttga atgatgtggt catcagcaag ggcacgcttg cccggatgat
      781 cgaactcaag attgcgattc agggtcagtt tgtcacgaat ttgcgcggtg acgggttgat
      841 catcagcacg ccgactggat cgacggccta ttcactctca gcagggggac cgattatcaa
      901 cccggccgtc ccctcattga ttctcactcc gatctgtccc catacgctga cgcatcgccc
      961 cttgatcgtc ccggcaagcg ctcaaattga agtggtgttg accagcaagg atgatggagc
     1021 aatggcgacg ctggatggcc aggtcggtgt ggccctgagt cagggcgaca ccgtggaaat
     1081 tcatgcctcc gagcacctga ccaggctgat ccgatttcca gagagcagtt actacgaagt
     1141 gttacgcgag aaactgaaat ggggtgacgg ctgactggca gcgggcgcgt tatgcgcgcc
     1201 cgcgttcgat gtgcgccagc atatcggcgt tcgaagcaaa cttgaattct ccgatggctt
     1261 caggtgatgc cgcgtgagcc ttctccacgg tatccagcac cttgaggcct tcgaggtcca
     1321 ccggcttact ctttcgttcc ttcaggatcg cctgcaattt cgacaggacc tggtcgactc
     1381 cactgactga ttggaccgac ttggtcgtga ggtagcgcga gatgacttcc gcacaccaat
     1441 ccccgtcccg cttggcaatt ccgacgagcc cttcgctggc tttgcgcgcc cacccggcga
     1501 gaaacacccc gtcgaccacc tgccctgatt tttcatcata ggcttggaat aacgaatcgt
     1561 ccggatcatt ggcggtcttg gtcgggttcg tgacatacac gccgttcttg tagggcaagc
     1621 caaccgtctc atcgacccga tcacctacgg caaagacgac actgtctacc gggaactcat
     1681 acagctgctt gagtccgacc gcggcggtgt cttcgccctt cggttccaat ttgttttctt
     1741 ccatctcgag ggcgcgcacg cggttgttgg catcgacgag cacccgtttt ggtgacgcaa
     1801 gaaaccggaa tcccattttg gaggagcttc ccgtcggttc gcacttcgta aattccgcgg
     1861 tcaaatttgc caggacttcg tcggcattct gtccgactgc ggccaggcgg tccttgatcc
     1921 gtgcgaattc ttgagcgatg ccttcgtgat ccatattcga gcagacggct cgaatttcct
     1981 tgggattata tttgcgctcc acgggcccgc gacgagcaat agccgtcacc cgttctacct
     2041 tcttgtagcg aatgagccag tgtgcgatgt cgaccatgac gtcgcctact ccgatgatgg
     2101 ccacatgttt gcccatatcg aacggacggt cgccgaaacc aggcaggcga ttgaagtggt
     2161 agaccacatc cttggcatgg aacacgccct tggcggagtc accttccacg ccgatggctt
     2221 ttgtgccctg ggcgccgatg gagaaggcca cggcactggc acccaatccc cgcagttcct
     2281 ccaccgtgag gtctttgccc tgcccgactg acacattgcc gaagtagtgc acattcggct
     2341 gttccagcat gtcccaatat tgtttcttca gaccgccgcg cagtttgagc ttgctgggga
     2401 aaatcccgta ctccgccaac ccgccaaact tgatgtcacg attgaggatg atgacttcat
     2461 ggccggcatc ggccattttc ttggccaggg ccattccggc aggacctgcg cccacaacaa
     2521 caactacatg cccgcttgtc tcggaaccgg ttgcactcat tatctaccct tcaatgtata
     2581 tcgataatag taacgcgtga tgaccttcga ccgtcggacg gccaaagaac ccaaaatttt
     2641 tggcacggta gcacaggggt tgtcgggctg tcaaaatcac gtaggcggtt cagctgcccc
     2701 gatgtcgacg gctttggggg aggctggtgt aaccccctcg tcgcctaccc tccggcgctg
     2761 ccgaccgggc caccggcctg ggtcatacgc cagggatcga gaagttggtt gagtcgcttt
     2821 tcaggcaaca cgttttgttc gcgcgccacc tcacggacgg tcttgccgga cttgtaggcg
     2881 tccttggcca gtttggcggc ggcttcgtaa ccgatgaccg gcgcgagcgc tgtgcacatc
     2941 gcaaggctct cctcaatgag gctcttgcag cgctcttcgt tcgccttgat gcccgcgatg
     3001 cacttcacgg caaagttggt cgaggctgtc gagagcagtt cgatggactg caagaggttg
     3061 taggccatga ccggcaacat cacgatcagt tcaaagttcg cggcctgccc tccgacggtg
     3121 atggtgacgt cattgccgat gacctgggcg cagaccatgg tgacggattc cgcaatcacg
     3181 ggattcactt tgccgggcat gatggacgag ccgggctggg tttccggaag attgatttcg
     3241 ccgaggccgc agcgcggacc ggacccgagc cagcggatgt cgttggcaat cttcatcagg
     3301 ctgacggcga gggtgcgtaa ctctccgctc gcctcgacca gcgaatcctg agcggactga
     3361 ccttcgaagt ggttcaccgc ctccttgaag ctacagccgg tttctttcga aatgagcgcc
     3421 atcaccttgc cggcaaattt cgggtgacag ttgagtccgg tgccgacggc ggtgcctccg
     3481 agggcgactt cgctcaaggc cgcctgggcc cgcttcattc tggcaatccc cagttcgatt
     3541 tgtctggcgt atccgccgaa ctcttgtcct aggcgaaccg gtgttgcatc ctgcaaatgc
     3601 gtgcggccga tcttgacgat cttgtcgaac tcgcgggctt tgccgctgag tgccttgtgg
     3661 agttgggtca gggcagggag aagctgccgc tggatggttt ccgaagcggc aatatgaatg
     3721 gcggttggaa tgacgtcatt gctcgattgt cccaggttca cgtggtcgtt cgggtgcacc
     3781 agtttgctgc ctctggcgcc gccgagcagt tcggtcgccc ggttcgaaat gacttcgttc
     3841 gtattcatgt tcgtcgacgt gcccgagccg gtctgaaaaa tatcaaccgg aaattcggcg
     3901 tccagccccc cgtcaacgac ttcggtcgcg gcccgaatga tggcgtccgc cggtttttta
     3961 tcgagcaact tcagcgagtg attgacggag gcggcggcgc gcttaatgag tcccatcgcc
     4021 cgaatcatgg cgcggggaat gcgtagcgaa ctgatcggaa agttttcaat cgcgcgggcc
     4081 gtttgcacgc cataatacgc attggaggga accggaagtt ctcccatggt gtctcgttcc
     4141 atgcgcgtgg cggttgtcgc tgatgcagtg ctcttgggcg tgcgcgaagc gttcttcatc
     4201 attgaatctc ctcgaatgac tggcggttga gctgcttgaa ccgcgcataa taaacgctcg
     4261 cccttctgaa gcacaagcat ggccttggag agaggaacga gggggcgctc agggagttgt
     4321 tgtatggggt gaagaagttc agggacgaac tgaaaaagaa aaggcccgcc ggaaggcggg
     4381 ccttgctctc tcaccggggt tcgttgtctt aggcgatttt gacgtcgatt tgtttcggtt
     4441 tcgccttttc tgattttggc agatgcaggt ggagcacacc atcggtatat tccgccttca
     4501 ccttactctc atccacggtg tcgggaagcg tgaagcttcg gacaaagcgt ccatatgacc
     4561 gttcgatccg atggtacttt ttccccttgt cttccttttc ctgcttccgc tcgccctgca
     4621 acgtgaggac accgtcttcg accgtgacct tcacatcttc ctttttgacc tctggaagct
     4681 cggccttaat ggcatattcg gcttcggtct cgctgatgtc gaccgtcggc gcccaatcag
     4741 cgacggtcat cacttccttg ccctgagtag cggtttgagc tgcgcccggc cgtgtaatca
     4801 tccggttcaa ccggtcagac atttcttcca attcccggaa cggatcccaa cgtacgatcg
     4861 ccatggtgga acctccttgt gtgaatgcgt tgctggtgtt cacttgagcc atcctactta
     4921 atacaaggaa ggtaatctcc acgccggtga agtcaagggt gtgccctgaa gagtaattgt
     4981 catgagcggg ctcttgacat tgcagccctc ggcattattt attagccccc ttcatattgg
     5041 agacgatcac catgttggaa ttcatttcct acgcattgct cggcggtatc ttgatggttg
     5101 cgtccatggt cgtatggtgg ttcatcggtc gtaccgaata gttcgccgtc ggtttatcgc
     5161 cgatcgatcg gcacgtaatg ccggtcatgt tccccggaat agatctgatc gggccggtag
     5221 agtttgtttt cccgcagttg ttccagccaa tgcgccagcc aaccgctcac ccgcgccatg
     5281 gcgaagagcg gcgtaaacag atcgacctcg attcccatct tgtcgtaaat gatgcccgaa
     5341 tagaaatcga cgttcgggta aatgcccttt ccttgtaatc gttcgctggc cagctgttcc
     5401 acggctactg cgacttcgta gagcggcgaa gtcccgcaga cattgaacag ccgcatgcaa
     5461 agatcctgta gcacggtggc gcgcggatct ttcaccttgt acacgcgatg gccgaatccc
     5521 atgagtttgt ttttcccgcc gagccgggct tccaccgccg cgcgagcctg cgccggcgtg
     5581 ccgatctcct tcaacatcgt caccacttct tcattggcgc ccccgtgtaa cgggcccttg
     5641 agcgcgccga tcgacgaggc cacgacggta taggggtccg cgagtgtcga cgcggtgacc
     5701 atgccggcga aggtggaggc attcatggtg tgttcggcat gaaggatcag gcagtcatcg
     5761 aaaaccgcgc tccacaacgg gtgcggaacg gtttccgtca gcatgtagag aaagttgtcg
     5821 gcaaagggca gatcgtcgcg cggcggaata tattcgtctc cccgtcgcaa ccgcgcccag
     5881 gcggctacga tagtaggcag cttcgcgatg agtcgcaccg ccgaccagta gttgttttca
     5941 acgtccttga cgttgcggcc cgggtaaaac atgcccagcg ccgcgaccgc ggcctgcaac
     6001 gcgtccatgg gatgcccatg ttcaggcatg accttcagca ggtctacaat acgaaacttg
     6061 atccgccggt ggtgtgtgac atcatccacc cactgcgtga gttccgtcgc agtcggtaac
     6121 cgtccgaaca acaggaggta actcgtttcg agaaaggacg agtgctgaca cagctcctcg
     6181 acccggattc cgcgatattc aaggacgcct cgtattccat ccacatcgct gatcgctgat
     6241 tttgcggcag gaacaccggc cagacccggc atgaaatcgt gcggcataga ttctgtctcc
     6301 tatcttcaac aatccgaatg gggcatcacg cgtgatgcga tcggttccat gagcggccct
     6361 cgtgtccggg cttcctgagt gacggtcgtc tggcctcagc ttatcacgat cgacggcatt
     6421 gactcagcct tcaccttgaa ttgaatggat tcgcttggca tactacctcg aaacgaagag
     6481 gacttcgacc gcggagaaca cggtgactcc attcgtacgc attcttctgc tggtcggact
     6541 gttggttgca ggcgtcgctc tgtggatgtt gcggatcgga gacccgccga ctgaagaacg
     6601 ttccgccgtc gccccgggat ccccacgggc aggacgcagc accctgagtc atggcggtcc
     6661 cggcgccgga tctcagtccg acaattcccc acgtcttcct gcaggcgaga ggaatgaatc
     6721 gtccacacag gctccacccg caacaacgag gtaaggcatg ggccggtttc ggtcgctcgc
     6781 gctgggagtg ctaatggtca ttggtctgaa tgtcccggcc tgggctgatg atgagcaggt
     6841 ctttttcgcg gtcgtcagtg atgtgccgaa agataagacg cgtatttctg cgaaggtcct
     6901 tcaggacggc gcttcctccg acatcaaact gattccgagc gagtcggtcg tcgccaatcc
     6961 cgtatggcgc acgctggaag tctgtcacgc actcaagatc gaaggtatga aaatcggcga
     7021 cggattgaag gtgatgtcag cccgggtgct ggatgccagc atgttgccga tgggactgca
     7081 agggttcgcg ggagattgcc tgatcaagaa agcggtcgag attgcgccgc tggcagagtg
     7141 acaagtctat cgtaagtcgg gaatatgtag ttgtgcgtcc tgagtcgtat cctgcttgtc
     7201 aggcgcactc cgggcaggtt gtccgttctt cttcctcgtc acattcatcc gccgtgaggg
     7261 ggaaaaactg ctcgcagagc cggcaggtgc ggatctcgaa ataggccacg cccttgtcat
     7321 cgatctccgt gggaagcagc agttcgaacg gatcgtagcc cagccggacg tcatcttcga
     7381 accggatgat ggccaagcgg tcattgaaga cctcaaacgt ggcttctttc cccttacgct
     7441 ccagccgatg tcccacgaca aacaccggtt ggcccttgcg tttggtgcgc aaatctttca
     7501 aggtgcgctg tgtcgcggtg gcacaggaga atttgccggt ctggtcgctc gtatcggttc
     7561 caaagatggg catcggtaat cacaatcgcg ttgatatgaa tcttgtgtgt ccatgtaaca
     7621 caggtgaaaa atttgcgtca agggaaccct catgaaggag aaaggttaac ggcatggcgg
     7681 agatcacgat ctatcagaaa cccacctgtt caacctgtcg agaggcggtg cgtctggtgc
     7741 gggagagcgg gcagccattt acggcggtca actactacga acaaccgttt acgaagagcc
     7801 ggctcaaaga gctgctgaag aaagccggcc tgtccccgcg cgatgtcttg cgcacaaaag
     7861 aagatctcta caagtcgttg aagcttgcgg attcgacgtt gagcgacgat cacttactgg
     7921 atcagatgat cgcacatccg gatttgattc agcggcccat cgtggtcaaa ggagacaagg
     7981 tcatgctggc gcgcccggct gacaccgtca ccgaattgct ctaaggttcc cgagagagac
     8041 gatgcaaggc ggggcgtggg tagcggattg gcggagggac agagatgttg gctttcgatt
     8101 ccgtagatcg ggtgtcactg ctgggacggg ttctgcagcg gctcaatctt cgcttcccat
     8161 ccctctttgt gttgttcgcc gttctcaccc tggtggatgt gattgtcccg gatgtgattc
     8221 cgttggccga cgaaatcggg ttcgcattgc tgacgctgtt gttggggatg tggaaggatc
     8281 gtcggcatca gccgcgacag cgaacggctg gcaaggcatt ccggtgaggg gcagagaagg
     8341 ttcggtcgag gtgagctcga ctacggatgg tccaaatgtc cgaagcggag tttgccgatt
     8401 tgcgggtcga tccagacttt gagattgccg gataagacgc tgagcagcgt ttcccccacc
     8461 agttggcgcc gccatcctcg caggaccgga atgtcaactt cttccaccgg cgacgtccgt
     8521 tccaccaagg cctgcaaatc gcccgtcgtg gcgatgagag tcggggcgat gttctccatg
     8581 gcagcgcggg atttcagcac ggcctgcagc agttccagca ccccggtgga ttcaggatcc
     8641 ggtttccggt cgcgtggcac ttccggccac tcggattccg gtctggccaa ggcctgctgc
     8701 atcgtggcaa gcagggcctg cccgttgcgt tcgacttccg aggaatacat gccgcgcata
     8761 ccgcgaagtt gatcgagcgt gcgcggggtt tgacgggcca actgcaccaa cacttcatcg
     8821 cgcatcaccc gccctcgtgg gacgttgcgg cggcgggctt ccccttcccg ccaggcggcc
     8881 aggtcgcgca acacgccggc ggcgcgcggc ttgaggctgt cccacccgcg aatacgctgg
     8941 taccgctcct gcgggtcgcg agcctgggct ccgagcgaga cctccaggcg ggagaattct
     9001 tcgtccaccc agtccaaacg gcccatcacc gacagtttct gacggagatg ccgatggata
     9061 ggcagcaaga aggtcacgtc atcgagggcg tagaccaatt ggtccttgct caacggtcgt
     9121 tgactccagt tggtgaaggt gtgagcttta tcgagtttca ccccctgcac ccgctgcacc
     9181 agattggcgt aagcggtctg cgcaccgtac ccgaccatcg cggcggcaat ttgcgtgtcg
     9241 aaaaacggct tcggcaatcg gccggcatgg tgcgcgaaca gttcgagatc ctgccgacct
     9301 gcatgaagca ccttctcgat gcgcgcatca cagaccagtt cccagaagcg gaccatcggc
     9361 gcgctgtcct gcacggcagg aaagtcgatg acggcagcca ccccttccgc cgcaacctgg
     9421 atcaattcca ggcgcggaat gaaatggtct tcacccatga actcggtgtc gatggcgatc
     9481 accgcgctgt tggccagctg gtcgcataac cggtcgagca tatggtctga ggtgatgaag
     9541 gtctgatccg gatccaatgt ggccatgggt tactcggtgg gacgatattc cgcgccgcgt
     9601 gaaatcggcg gttcggtgtt gctcaagctc agatattctt tgaggaactg ataggcttcg
     9661 agaatgcgcc ggagttcggg ctcggaactg cggtcgccgt tccgggcatc gggatgcaat
     9721 tccttggcgc gttgacgaaa cgctgtggtg acgtctgcga gcggcgtgcc gaattccagg
     9781 cccagcaact gataggcgtc gtaggcgttc gtgacttcgc tggacgtacc ggcgggattc
     9841 ccctcccctc cggcggcttt gaggaaatcg gcgagattga tttttcgccg gcgccgtcgc
     9901 gggcgttcac gtatctcgct gtcaagctca tcccagcgat cttcgacgaa ttccaggcgt
     9961 gattccaaac gaatggcccc ggacacatcc ttcaccaggt ccaattcgtc ttcgatctgt
    10021 cccagcgaac gttcgacttc ttccaaggcc ggttcgatgc ggaaatagct atcgacccgt
    10081 tcctgcatca tgaaatcgac ggcaaactcc atgctgtcga tattcttggc gcgcagcatg
    10141 ccgatccggc gccgcatgcc ccgctgatat ttgaacaggc gattggttga aaatgccacg
    10201 agtcctcgtt aggcgtgacc ttgcaggtaa gaggcaagtc gatcgcatct tagcacatca
    10261 ctttgtccgg cgataagagt cgattgagtg aatcgttgct gcgtcgcagg ctacagacac
    10321 cagaacatgg ctgccgcgat cagtgtgggc ggcagcgcgg ccaggaacag tcggagcgga
    10381 tgtaccgcct cgtcgtcgaa ataggtccgc aggatggcca gtccggccgg attcggcgca
    10441 ttggcgataa tggtcaagcc accgcccgtg acggcgcctg ccaccagggc atacttaaat
    10501 gcatccgaaa ggccttcgac gagcgacccg agataggtca gagcggcatt gtcagtgaag
    10561 gcagtcagaa tcgtggcgcc tacgaacacc gcatcggctc ccatgccgag caggatcggc
    10621 tgcagccacc attgttgttg tccgcctaag accaccaggc ctgccaggaa aaaagagacg
    10681 agcaaccctt cgcgaagaat cagacgatcc tgatactgct cgtaggcctg cgcgatcccg
    10741 agaaacaaca gcaggatgcc caggaacatc gcgggatggt gggcgaacac cacgaccatg
    10801 gcgagcaaag caagatgtgt gatcaccaga gccagtggcg cgcggttctc ctcgcgttga
    10861 tcgatggcgg tcgagatgcg gctgagttct cgacgaaaca gcatggttgc cccaaacgca
    10921 ttgatcaata cagccaacgc cgctttccaa ccgaatgtgc ccagcatgaa tgcgatatcc
    10981 cactgccagg caccggccac cattaacaca ggcggcgcag cgaagggagt gagcgttccc
    11041 ccgatggaca cattcacgaa gaggacgccg agagtcgcgt atttcaggtt cgtggagcag
    11101 ccatggcgaa aaaagacatc acgcagcagg agtgccgcca acgtcatcgc ggccggttct
    11161 gtgatgaagg atcccaatag cggaacaagt gccagcacgg tgagatacac ccgcattccc
    11221 tgtggcagcg ggatggcact gctcacaata cggactcccg tcatggcggt ctgtaagatc
    11281 ggcctggttc ctgcgatcac catgatggcg aagacgaaca ggggttccgt aaaactgcgg
    11341 gagtcgagat agtgcgtggc ggcagccgca ccgtcggtga caaacatggc gacgatgagc
    11401 acgagagccc agaatccgaa cgcaacctcg acttcaccga gcaaatgcca gaggccggca
    11461 tgtgccggtc tggtatgcgc cagatgttcg aagaatgccg tcgcaaacgt gtgcaggatc
    11521 gcgacggcga acaacagggt tccgatcagt tgaatggtgg ttggcgtcac actggattcc
    11581 ggatgatctc actgaggcgg aggcaaagcc acgagagacg ggcgacggcc tcgagcgtcg
    11641 gccctactct acatggattc tgcgtaccac gccaatgttg cagaaaaacg attgatcact
    11701 gtgcgcaagc ggagatcgga acggtgagcg gcctgggtca gcgggggtcg tcttcgattt
    11761 tgatgcggcg tcgggcgaca ccggtggtgc gagccgcggc cgccacggcc ttggccaccc
    11821 gcggcacgac gtcgcgatcg aagacgctgg ggataatata gtcttccgac agcgcttcgg
    11881 tcggcacaca ttcggcaatg gcctgcgctg cagccagctt catggcttcg ttgatttcgc
    11941 tggcttgcac gtcgagggca ccgcgaaaaa ttcccggaaa cgagagggca ttattgattt
    12001 gattgggata gtcggatcgg ccggtagcaa aaatgcgcga cacttcatcg ccgatcttcg
    12061 gatcgatttc gggatcggga ttggccatgg cgaacacgat gcgatctgag ttcatgttgt
    12121 cgagatcggc tttctccagc acattcccca ccgagagccc gatgaagaca tcggcgccgc
    12181 gcaaggcgtc gtgaatggtg ccgcgcggct ggtcccgccg gatgcaggcc tgaaggtcgg
    12241 tccggcaggc gcggagttcc tctgcctccc ccatcaacac gatgccttcc ttgtcgcatc
    12301 cgacaaggtg acaggctccg gcggccaaca gaatgcggca acaggccgtt cctgctgcgc
    12361 cgaggccatt caccacgatg cgaacgtcct ccatccgctt gccgacaacc ttcagcgcat
    12421 tggtcaacgc tgccagcaag acaacggctg tgccgtgctg gtcgtcgtgc atgacgggaa
    12481 tgtcgagcga ggtcttgaga gcgcgttcga tctcgaaaca acgcggggcg ctgatatctt
    12541 ccagattgat tccgccgaac ccgggagcga taccgcggac gatgcggatg atttcttccg
    12601 gatcctgtgt gctgacgcaa atcggccagg cgtcgatgcc ggccaattcc cgaaagagca
    12661 tcaccttccc ttccatcacc ggaagcgccg ctgccgggcc gaggttcccg agcccgagaa
    12721 cggcggaccc gtcggtgacg acggccacgc tattgctctt gctcgtgaag gcataggctt
    12781 ttaccggatc cttggcgatg gctttgcaga cgcgtccaac gccgggcgta tagatcatgg
    12841 acaaaacgtt gcgggtcgtg accgggactt tactctggac tctgattttt ccgcccaggt
    12901 gcaggaggaa gatccggtct gaggccgaca ggacattcac ttccggcagc gcttccaggc
    12961 gctcaagcac ccggtcgcca tgcgcctcat tctgcacatc gaaggtaatg tccctgatca
    13021 tgcgctccgc attggcggac acgatatcga ccgcccccag gttggctcct tcctccgcaa
    13081 gcagggcggc cactttcgcg aagatgcccg gtttgttgag gagcgcgagg cggacggtca
    13141 ggcggtagtt ggagtacggg ccgatgtcgt cggtggtcat aggattgatc cgagaccgtg
    13201 tggattactt atgaagagtg tatcacagcg cggacggatc tgagcttctg gtgaagcatg
    13261 acgtttcctg cattggcctc cttccacttc gtctatctca cgaagaagtg tcccatcagg
    13321 gtggcacttc gtgaaggccg agcgttgatg ggttcgcggt gaaccatagg ctgtcgagat
    13381 ccgttaacgt ctcgaaaagt aaagcgctcc agacatcccc ggcaggagga ggccgtgacg
    13441 catccgttgg atgacgaggc tggtgaaata tacgcaaaga gtttcgttga ctttttctga
    13501 caggttggct accctcgggc gcccttgtgg tgtgggcact tatattctca acctttcaag
    13561 gaggggtttc catgaagcgt gctctattcg cattcgtagc ggcagccatt ctcgttgcgt
    13621 tcaccgctcc gtctttcgcc ggagatgaca agaagaagga agagaagaag ggcggccact
    13681 tctcccagac cctcttcggt gacgacaaga agaaggaaga gaagaagggt ggacacctgt
    13741 cccagaccgt gttcggcgaa gagaagaaga aggacgagaa gaagggcggc cactgagccc
    13801 cgctttcgac gttctgtcgt agtataaagt tggctcgcga cccgggattg ccggcgcggg
    13861 ccaatttttt tatctcttcc gccccttccc tgcccggctc cccgcttcat tgacccattc
    13921 actgagcccg tgttacggtt cgcgaatgac tgatcaccac gcgaatcgcc ccgccaatcg
    13981 gctcattcga gaaaccagtc cctatctctt acagcatgcg tacaaccccg tggattggta
    14041 tccctggggg ccggaagcct tggctcaggc cgcagcactg aagcgcccca tcctgctctc
    14101 catcgggtat tcctcttgtc actggtgtca cgtgatggag cgggagtcgt ttgaaaacga
    14161 ggcgattgcc gccctgatga accaacactt catctgcgtg aaggtcgatc gcgaagagcg
    14221 gccggatctg gatgaaatct acatgcaggc gaccttggcg ttgaaccgca atcaaggtgg
    14281 ctggccgatg accgtcttcc tcactccgga ccagaaaccg ttttttgcgg gcacgtattt
    14341 tcctccgaca gatcgctacg gtcgtcccgg cttcccgacc ctgttgaaga agatcgccga
    14401 gtactgggag aaggaccacg atggcgtggt tgcgcaggcg gtgaatctga cggcacggct
    14461 ccaagagggg gctcacgcgc cttctccgac gacagtcggc gaagcggaac tcgatatggc
    14521 cgtgacccag tttgctgaag attttgatgc gagacagggc ggcttcggcg gcgccccaaa
    14581 atttcctccg gccacagggt tgtccctgct cctccattgt taccagcgca cgaaggatcc
    14641 ccatacgctg acgatggtgc gcaagacgtt ggatgccatg gcggcgggcg gaatctacga
    14701 tcacatcggc ggcggtttcg ctcggtattc gaccgacgaa cgttggctgg ttccgcactt
    14761 cgaaaagatg ctttatgaca atgcgttgct ggctcgcgtc tatgtcgaag cctaccaggt
    14821 cacggcagac gagacctacc gccgggttgc ctgcgagacg ctggattata tcctcaagga
    14881 aatgacgtca cccgagggag ggttttactc cgccaccgat gccgattccg aaggcgtcga
    14941 gggcaagttc tttgtgtgga cgccggaaga cgtgcgagcg gcggtggaca gtgatgaaga
    15001 ggcgcgccgc ttctgcgcct attacgatgt aacggcgggg ggtaactggg aacacacgaa
    15061 tgtgctccat accgcgaaga gcgtcgaggc ggtcgccaag gaactgagca tcactgccgg
    15121 cgagttaact gaaaccatca cccgtctcag accgaagctt tacgcagtgc gtgcgaagcg
    15181 cattgcgccc ggcctcgatg ataaggtgat cacggcgtgg aacgggatga tgatcagcgc
    15241 catggcggaa gccggacggg tgtttgacat accccgttat cgcgaagcgg ccgaacgggc
    15301 ctgcgatttt ctgctgacga cactctcgac tgccgatggc cggctccttc gaacgtatcg
    15361 tgcgggtacc gcccacctga atgcctatct ggaagattac gcctattttg ctgaaggctt
    15421 gatcgatacc tatgaagccg ggggcgagga acgctatctg ctcgcgtcgg ttcgcctcgc
    15481 cgagcggatg ctggcggatt ttgccgacag ccagcacggt gggttcttca ccaccgccac
    15541 cggccatgag gcgttgatca tgcgcagccg tgagggacca gacggggcca cgcccagcgg
    15601 caacgcggtg gctgcctcgg tgctggctcg attgtcttct cattttgccc gggaggattt
    15661 ccgcgaggcc gcgaccgccg ccgttcgcgc ctatggccgt cagattgcgc gctacccgcg
    15721 ggcatttgcc aagagcctca tcgtggtcga tttcctcatg agtgggcctg cggagattgc
    15781 gttggtcggg cggctcgggg atcaagggat ggagtcttta cgggccgccg tgaatcgcac
    15841 ctaccttccc aatcgcgtgc tcgttcatcg cgactcagat cagagcgcaa ccagtcatcc
    15901 gctcctgcag ggaaagacgt tgatcgacgg caaggcagcc gtgtatgtgt gccggaattt
    15961 tgcttgcggc cggccgatca ccgatccgaa agaatttccc tctctgcttg atccccggca
    16021 acaggcctcc tcacctcccg catcggagca gaagatcttg agcggaacgt tatacccggg
    16081 ccatgcgacc gtgcagggca cagcggctta tgctgcgcga cacattcacg agagcaacgg
    16141 ggcgctcgcg catggattcg ccctgtttgg tgcgactgga ctgacagcca gtcgattagg
    16201 attcggaacg tatcgagtcg gccagcggga ggccgaacat cgtgaggcct tacgcagcgc
    16261 attgcgccag ggctgtaatg tgatcgacac ctcgaccaat tacatggatg gtgagagtga
    16321 gcaattggtg ggatcggtcc tgcgggagat gatgcgcgcg ggcgatctaa cccgcgaggg
    16381 cgtcatcgtg gtgtcgaaga tcgggtacgt acagggccag aatttgacgc aggcccaggc
    16441 gcgggaaaaa tcgggcaaac cctaccccga catggtcaag tatggtgacg atatctggca
    16501 ttgcatccac ccggagtttc tggcggacca actcacgctg tcgttggacc ggctggggtt
    16561 agccacgctc gatgtgtgcc tgctccataa tccggaatat ttcctgtccc atgccacgcg
    16621 tctcggcggc gatgagtcgc gcgacctgcc tgcgttacgc caggagtttt atgcgcgact
    16681 tcagcgggcc ttcgagtatt tcgagacgca ggttcaggcg ggtcgcttgc gtggctatgg
    16741 tgtctcatcg aatacggcca cgtcagctcc cgacgatccc ggtgccactt ccctgtctca
    16801 catgatcgac gcggcgaagt tggcggccac gaccgttgga gccccgtccc atcacttcca
    16861 ggtgctccaa tgtccgatga atgtgtacga gtcgggcgca gctctgatca aaaacaccgg
    16921 gattcacaac ggcagcacgc tgctggagga agccatgcgc gagcggatcg ccgtgctggt
    16981 caatcgtcca ctcaatgcga tgcccgtgca gcgcggagga gtgattcgat tggcggacgt
    17041 ctcggtgccg gctccagagg ccgatttcga ggcgcagcga aagaaagtcg ccgcattgga
    17101 ggaggaatat cgcaacagtc tcgcccctgc agtcgcgcac agcggtcagg gcatgctacc
    17161 cgccgacttt tttcgatggg ccgatgagtt gactcgaata cgaggccagg tgcaggggct
    17221 cgagcattgg gaacaaatcg aacagcagat gatcgcgccg cacgtgaacc aggtgcttcg
    17281 tgcgctggcc gaggcgttta ccggaaacgt cgctgaacag tgggagtcct ggcgggaccg
    17341 atacgtgccg gaattgttgg cgctcctgag aattctgcat cgggaggcat cagaaaaaag
    17401 ccgcctccgc tccgatgaac tccatcacac catgaatccc cttctaccgg aacagcgacg
    17461 cacggccacc ttgtcgcaaa aggccctctg ggtgctcgcc agcacgccgg gtgtcacctg
    17521 tgtgctcaac ggtatgcgca cgccggccta tgtggaggat gcgctcacga ttctgcagtg
    17581 gccccccttg ccggagtggc gatcggtcta cgatcgttgt gccgggaaga agtaacttgc
    17641 caggttcgca tcttttgatt attctgtgcc tcgtctggtc cacgaactca cctagcgccg
    17701 gaggttttca tgatcgtttt gcgcccgttt gccttggttg gactgttagc cgtcgccgct
    17761 ccctttctgt ttgacggctg cgcgagcaag gcgggaacca gtggaggagc caccgtaact
    17821 ccttccaaac cccgtgtgga ggagcggatt gctgctgctc ctgttcagga aattcctccg
    17881 gctcccgaac cggcgccggt tcccttgcgc tcagtggaaa tggccgcccg taatgcgacg
    17941 ggggaacaga atatcccctt ccctgatgtg ttgttcgatt tcgatcagta tgttctgcgg
    18001 gacgatgcgc tgaatgccgt cgaggcgaat gccaaacgat taaaagacaa tcgggtcacc
    18061 aaagtgttgt tggaaggccg gtgtgacgaa atcggcaccg cggaatacaa cttggtgctc
    18121 ggcgaacgtc gtgccctttc cgtgaagcgt tacctggaat cactcggcat gagtcaggtg
    18181 caggtggatg tcacgagtta tggcaaagac cgtcccctgt gtttgcagca taatccggtc
    18241 tgttggcaga agaatcgcag tgtgcacttc gtcgtgaaag aataaactcc ccccatctgg
    18301 ttgtgacgac ggcggcatgg gcgtacgtgg cccatgccgc gcttggttcg acgttcttcc
    18361 gactctccgt cagtcgtaac aaagatttta cctgcccata acccgctttc aatatgcccg
    18421 ttctatcctt cgagttagag actcagaagg gcgtgtttct gagtcaaccc atctaaccag
    18481 gaggatcgga tatggtgact gtcagcgagc tcatgacgaa gaaactggta acggtaccgg
    18541 ttggcacaac gacggccgag gccgctaaag tgatgaatga gcgtcatgtc ggtagtgtgt
    18601 tcatcgagca gaacaatcgt gttgtgggca tcgtgaccga gtccgacatt gttcgaaaag
    18661 ttgtcggaga aaacaaaccg gtgcattttg ttccggtcga atcgatcatg agcagcccgg
    18721 tcatcagtct cgacgagcgg cgatcgatta ccgaggctgc cgatctcatg cagtgccatc
    18781 acactcgtca tctcggcgtg ttgcagagcg gcgcgatcgt cggggtgctc tcggtgcgcg
    18841 acctcttgca gccggtcgcg gtggacgagt tctaatcgtt ttttcacagt gcattggcgt
    18901 tcgtcgtttg gctgagcgct ccgatcgcgt gtgtggtcgg agctccgaca gccgcaagac
    18961 gttgctccga aacctctctc ccgttcactc ttccttgtgt cagtcacagc cctcagccga
    19021 cagtgttcct cacgacatcg gagacatccc ttggctggta tggctgcgaa taccgtctcg
    19081 acatgcgagg gcaacggtgt agcagtttct gccgggagtg gccttgtctt cgtgctatcg
    19141 aagtgctact tgcgtagaga gtcgaggctt gtcgaagagg atccgttcag tcggtggtta
    19201 agaccgagca cgatcaggtc aggctgcatt cacgctccaa cggggtccat cccgctggca
    19261 tcggactcta ggggacgatt taacacatcc gtaacatgcc agtgatgaag cagcaatcat
    19321 cggttagtag gatacataca gttatagccg ataccaccac tctagcggag gagaagagca
    19381 tgttaagtca tggacagaag catggatggc gacggcgagc agtggttgtg ggattggcag
    19441 gaatccttgc tactgctgag tcgttggctg tgcttccggc gggagtcgca cgggccgaga
    19501 acgccggacc aacggcgagt ctggccattc aagaaggatt ggtacaatac aatccgcaga
    19561 ctcaagtggc gggaagcctt cgggttcaag gttccgatac gatgtctctg cttatgagtc
    19621 gtcttgcagg tgagtttcaa cgacgccagc cgaatgtctc gattaatgtg agcgggggtg
    19681 gatcgaccaa agctgtgaac gagttcgtcc agccgcccgc caaattgagc gggaaaatta
    19741 ccctcaagga agaacgaccg acctatgtct ccctggtggc gtcctcacgc gagttgcttg
    19801 atgccgaagt gaaacaattt gtcgcccagc atggatatga acccaccgcc atccccgtcg
    19861 cagtcgatgc cgtggcactg tatgtccatc gtgataatcc gatccaaggc ctcacgctcg
    19921 accaggtcga tgccatgttt tcaaccacgc acaaccgcgg attaaaaacc agcctgtcgc
    19981 aatggggggc tctgggactg caagacggtt gggagaaggc tcccgtcaga ctctatggtc
    20041 gagatcggcg atccgggacg cgcgcgttct ttcaggaaca ttgcttagcc ggtggcgaat
    20101 tcgcaccgtc tgttcgggag gaaccgggtg ccgcatcggt cattcttgat ctgacgcgcg
    20161 atcaattggg tatcggatac agtggattgg gccttgaaac gtccaatgtg cggatcgttc
    20221 cgctcgctga gaatcagggc atgccattta tcgcaccgac ggcgacaact gtttccgacc
    20281 aaacgtatcc ccttcgccgg atgctctatc tgtatgtcga taaatctccc aaggctgccc
    20341 tcgcccctgc tgtgcaagag ttcctgacgt ttgtgacgag tcgtgaaggc caggaagccg
    20401 tgatgaaggc gggatttttc cctcttccga tgaaccagct gaaaaagaac tttctggcgc
    20461 tcggcctttc cggccaagag actcccctcc caaactgatc caccgtcgtt tcgcataatg
    20521 gctactgccg caggtcatcg agactattcc tcgatgcctg cggtgcaaac cgttctcatc
    20581 ctttcctcgc tgaccaactg cgtctcccgc cagcattcga gagaggctac ccgccttcga
    20641 gaattatcga tagcctgaat acttattgct cgtgcgttgc accaccgtcc tcgcccgaca
    20701 gaatggctga cctagggggc cggaacttcg gcctgatgcg agcggccgag cgggtaacgc
    20761 agcacatgac gataccggat gttacgccaa tgtgtagatt gtgaggcgcc gaacatgcgc
    20821 agccgtcagg ttggcgtgat tcagcggatc acggatgcga agaggtgagc ggctcgcctt
    20881 attggatcgc gcaatcgctg ctcactgggc cggtactcct ctcgaggaga aacaccgagg
    20941 tgtctcacga tatgagcgag gattccaaca acggattatg cgtagatggc tgatagtaaa
    21001 ggtgtggatg gctatggggt tgtagatcgg cgaggtgtct tgctttttgc tcgagcggag
    21061 tcaaggtctt gttgaagttt tgttaattga tcctgcaacg cctgcatctg tttcagttga
    21121 gtatctaaac gattccgaag ttccagattt gaggtcgtca gctcacgcac ttgcaggcga
    21181 agctcatcgg tctgattgcc ggtcgtgtcg gctggcccgt tgctctttgc gccggctccc
    21241 actgcctctg atgggtgaag cgatattgag ggtgaaacgt cagccgaggg agaagcaggc
    21301 cggtttctgg cagcaatgac ctccttggca ttcagggaga cgtgtactgt ttcaaaatga
    21361 gcccagcgtg gctcttccgc atcgggtacg gtggctgctg ttgccggagc ggtgacccac
    21421 aacttcattc cttttgtatc tcggagatcc ttcacctccc ctccggccgt gtccgccctc
    21481 gtgaaggcgg agtggtccgt gagcacgacg tgaagatatc gtcctcgaag aaagagcgca
    21541 ccggtggtcc gttcttcgct ataggtcgtc tgtgatttag gtaaggaaaa aaacacgcgc
    21601 tcgctgggag ttgcttgttg aaaagcggct gcgaccggcg cggcgatccg attcaattcc
    21661 agctcagtga agacagggat cggacggggc cgttccagga tgcccaccag cgttccgctc
    21721 caaccactca ccatcaacga accgagaagc acgcgcacct cctccgtggt cagctgcgca
    21781 ggatggttgt tttccgtggg ggcaggtccg cgatggacag tcgggtccgt ttgcactccc
    21841 acctgactgt cctgttggtc gaacagcacc tttcctccgg tcaatagcga gcatgcggag
    21901 gtcaggtaca tgaggagaac gaggcagagg ctgcggcgca atgccagccg gggatagggt
    21961 atggtgacca tcgacgctac tggcatgtga actgaattcc ccatactctg tcccctccca
    22021 tttgtcctcg ccaggctcga tccgcagcgc ggctcacctt tggtatttcg ccttctttct
    22081 gaactttgaa cccagccggg catttgcggt tgatcaactc catcgcgtca cgccgctcgc
    22141 tggaagtgag gacatcgact tcattttgga aggggtacgt gacgagccct cctgtcggcg
    22201 tgtcgcgaac tagggtcacg ccggctccgc aggcgctgca tgcccacacc agcacgagag
    22261 cggcggtcac atcaagtgtg cgaagccgcc ctcgtgaagg tggaatactt tcagggcttg
    22321 tcagcgggat tcggcgcaat acgtctcctc ctcgagtggc tgatatcctg ccccaaagtt
    22381 cgggaaatca gcaatctctt ttcccccggt gttccagata tgtaggcact gggccgtgag
    22441 agcgggcaga ctgcgttggc tatcctcgat agcgaccacc gccgcgtttt gcgtggtccc
    22501 gatggcaatg acgcgattcc cgggctgcag atggtttgtg ggaaccttgc cgttaaaata
    22561 caccagaaat tcacccctcc cccgttccgt atccgtcgga ccataggccg ggtgttcgac
    22621 aatcggcaat tgggtcagca ccatggtgac caggccgtct ttttgcggag cctgcaggat
    22681 gcgaccaccc agttgcacct ttttccccgc cttggcattc ggcaccatgc gccaggccgt
    22741 aaagtcgaaa tttgggtcca ccccgtccag cacttgaggt gagaagacgc gttgtggtcc
    22801 gcatccgttg agcactaaac cgatcagcac cgccgcgatc gctccccggt atatcttcat
    22861 tgctagcctt tctctttgct cgagaccgaa tcggttagac agttgttgcc gcagttgcag
    22921 tcatcccgtt acatgaatcg gatttgccac tgtaccaaga aggcattctg ggcgaaaggg
    22981 tcgcccacac cgcgcgtcgg atcgacgaca ttgttaggcc cgttgcccga gtgatggcgg
    23041 aactcgtaat tgacttgcag tttggactgc accttcggcg gaaagttttc gaaatagtag
    23101 ctcaagccga cgatggttct ggtgtagaga tcattgccga tcctggtatt cgggtcgaat
    23161 tgttcataca tgatgaccgg ctcgaagttt tcgaaggggc cgtcagtgat gagatatttg
    23221 gccagtacgt accaggtacg tcgttgtacc cccggtgcgc cggagccgcc gcagatggct
    23281 tggacatcgc aagcaccgtt ggccgggcgt ccgactgtcg tctgattggc cccatcatgc
    23341 ccctgccata tttctccctg caccatgaag ccaggaagaa ttttcgaggt ataccgaaag
    23401 tccagtccat agcgatcgaa ggctcccttg ccgcgaccat tgatgttggt gttggcgttg
    23461 ttcgactcgc cttgaatcgt ggtgaaactg ataaatgaca cgtcgctccc gaacaatcgg
    23521 acgcgggagt agaagctttt cggcgcgttg gatccggtcg cgttggcctc atagttgttg
    23581 ttgttcataa taccgaccac atactccagc cggttgaaca gtttcccgcg catatcgagg
    23641 aagtaatccc gctcttggag aaactcgacg gtgccagccg acccggtacg attgccgacc
    23701 ccagagccca ccgaggtaag gtagggagag ctgatgacat cgcgcaagcc gccggaggtt
    23761 tccgtgaaga tgccgaaggg cattcgaaag atacccatgc ggaaataatt cacgttgggc
    23821 gcccacgact gcaccggtcg tatgtcgagg taggcttccc gaaagaatgt cgacgaggtc
    23881 ggcactccgc cagtggccgc gctgcctcct gtcggtgtgt tgttcaagag attgatgctt
    23941 tgaaactcca tcaaggtgtg ccatcgcggc agggtgtcgc tgatacggcc ccagaagaga
    24001 atttccgacc ggcggatgga taggttgtcc tgactccgtc cttcgggcac atgcgcatcc
    24061 tggtgcgtgt acaaccattg gagtgcgttg agtccgaagt tcaccttatc cctaaggatc
    24121 ggcagcaact cagccttgga cttccactcg tccaagctat cgacccgttt gtcccgctct
    24181 ccagctttgt attcctgttc ggcccgaatc tgaatccact cttctttggt gatcgtgccc
    24241 ttctgcataa gcaggtcttc gattgacgtg ccgcccagag gcatatccgg cgcaggcggc
    24301 ggactgctgg ttccgttcgg agccgggccc attgcctggg ctaccacggt gtgtgacgac
    24361 tggccctggc gtgaggaatc atcggcccag gacgctgtta cgcagagccc gagcatcgcg
    24421 ctcccgacaa ggccgctgat ggatgcaacc aacggacgca tttccattac gaacatcctc
    24481 cttgtagtgt ctgttaatgt cgtgaaagcg gtgggattgt aattgcgagg catcacaccc
    24541 acgttcaatc tctgttaccg atgtgtaaaa ccgtgtcgtg cgtcattgat gtctgttgcg
    24601 gtgccgactt atggcaacgg ctcaatccgt ggacagtttg taccccacgc ctctgaccgt
    24661 gagaatccat tgcggagccg acggcttagt ttccaatttg tggcgcagtg cgtggatatg
    24721 cacgtccaag gcatgttctt cgagcgcgta gtcttctccc cagacaaggt tgagtagttc
    24781 ctggcgcgtc agcacgcgcc ccggatgctg caagagcacg cgcagaatct ggaactcctt
    24841 cggcgtgagc tggatggatt tgccttcgac cctcacctcg tgtcgatcga gattcatgca
    24901 tagcgtattg actcgaaatt ccctgagggg cgcagcttgt atttcctgtc gtcgaagcag
    24961 ggccttgatg atcgccagcc attctcgatg ccgatgtgag tcgatgacga tatcgaatcc
    25021 ggcggcaagg tcctccacgg tctcctcttc cgtacacggt tctcccaggg gttgaagcgc
    25081 gatcatcggg atgtgccgga atgcgaggtt ctgccgcaac gtcccgacga ctttgtgacg
    25141 ccggtcgatg agcgccagtt tgaacgaggc accggaagca agagacaagg cggcctcagc
    25201 ggttggtgcg agagacacat gatacccgtt cggccgtaac agctggtgga cagacatggc
    25261 aaattcttcg tctttggtga caagaagcac cggaatgccg tgatgacgta gcggttccgt
    25321 cgcgtgctgc atagcctgat gctagcggca tcgagttgcc tgcctgtatc ccgtttgtta
    25381 cggctgtgta aatactgcag tgagatgtcc gcatggtccg ctgaggcggc tcgcccctag
    25441 aaaacgtaac gctgctgtaa tgccgttgtg aatatcacgg aacaattcag cggtacagtg
    25501 gcgatgaagg ttatggtcca tggggatccg gggacggacc tctcgagcac gttgctcaac
    25561 catgatcgtg tcattcacca ggaggtttca cagatgacgt ttaccagttt ccccgttcgg
    25621 gttccccgtg tggcagatct cgcagggcgc gccatcgaaa cggatctcac cgacctctgg
    25681 atgaagggta ttaaagccgt gctgagtctt ctgattctga cgatcctcat cgccctgacg
    25741 ggcggggtca tcaagacatt tctggatatc aaattgttac ttgaggctcc ggttgaggtt
    25801 gggcttcggc agattattgt ggatacgctc atccttctgg cggtggtcga agtctttaag
    25861 acgacgctga cctatttttc ggagggacgc gtcaaagtga catttattgt cgacacgatt
    25921 ttggtcgtca tgctgacgga gatcatttcc ctgtggttca aagaagccga ccaaacgaag
    25981 ctcctgtcgt tgggtgccat cgttctggcg ttaggggcgg tacgtgtcgt cgcagtgcgc
    26041 tgctcacctg ctcagggtga tggcaacgga aaatgcgcag gatcctgccg ggagggaatc
    26101 taattccttc gcgtacaggt gacaagtgct cgcatgttca tgcagggttg agttgaaaga
    26161 gaggcgcatg ttgcacagtc agctgcatgt gatccagcag tcagccggtt gccagggaca
    26221 gcgagtagaa ggcttgggga cattccaacc aggaggatcc accatggttc atcagtctgc
    26281 agtgctgagc agtgagtgca gggttctgga gttattgcat ggcaggaaat cgcttacgct
    26341 tgagcaggtc gtcacactcc ttcccgaact gagctggaat caggtcttca agacgattga
    26401 tgagttgagc cggcatggga agatcattct cttgcgaaga gggtttgatt acgaaataga
    26461 acggatctct tcccgtcaac ctgcattgtc ctgctttggg tgaaggcgtg atctgcggat
    26521 tgcttacgta tgatgggcgt caaagccgtg acctgaatcg atagcgaaat cccggcaaca
    26581 tgtcgacgga tccggccccg ctgttctcca gttttcgacg cagaccacgg acgtcgtaat
    26641 ccagttcttg gagtagcagc cccggcctct ccccttccgg aagcgttaac aactcttctg
    26701 cagccaccaa ggcattttcc cgaccgagta aggtctggag cagcgccgtc tcctttcggg
    26761 acaggagcag ttctcgttcc cccaacagaa cggcaaaata cggcccctgc atcctgacag
    26821 ccgcattcac aatgggggcg accccgtccg ctgagtgtgc acctcgacga agaacagtgc
    26881 gcacgcgcga gacgacctct ctcggactga atggcttcac gacataatca tctgcgccca
    26941 tatcgaggcc ggcgatccgt tcgggttccc ctccaacggc tgtcagcatg atgatcggga
    27001 tgtgccgggt tgcggaatgt tggcgcacca tccggcagat ctcttgacca ctgagtgccg
    27061 gcaacatgag gtcgagcaga atgagtgtcg gtaggcggcg ttgaatctcc tgccacccgc
    27121 tggcgccgtc gctggacagc aaggtgtcaa agcccgcaag gcgtagtgca cgatcgagca
    27181 gtccggcgtg gagcggttcg tcttcaacga tatgtacggt cgagggtctc atgacataag
    27241 agggtacgga gcgacggttt cagattcctc acggcgagat gtcggtgtgg ttaactcgag
    27301 aagccgatca cgattctttc atcagaaagc gaggctcacc gagagttaac acggtgttta
    27361 cattgggctg atggtctgga aatgaaacgg ccgtatgctc gacggtgcaa tagtttacgg
    27421 ctcttttaac cggaggaatg tcttctatga ccgtctcacg ccagatttgc ttgagtctca
    27481 cgttgaccgc gttaggccca tttatgacga tgtgcctggt cagcgcagcg ccgggtgata
    27541 ctcccgcggt cgaaacgctc actgttgatg ccggtatcaa accctatcat aaggtcagcg
    27601 gcgtgtctgg aacgatcaac agcatcggat cggataccct caacaatctc atcaccctct
    27661 gggcggaggg attccgtaaa caatatccca acgtgaaaat tcaagtagaa ggcaaaggat
    27721 cgagcacggc cccgcccgcc ctgatcgaaa acacggctca gctcgggccg atgtcgcgaa
    27781 caatgaaatc gagcgagatc gatgcctttg aatcgaagtt cggttaccct cccactgcct
    27841 atccggtggc ggtagatgcg ctggcgctct tcgtgaacaa ggacaatccg gtggcaggac
    27901 tcacgattgc cgaagtggat gcgttgtttt ccaagtcgcg acgccagggg cacaccacgg
    27961 acctgacgcg ctggggacag cttggccaga acggcgattg ggcgaatgcg ccggtcagcc
    28021 tctacggtcg caactcggcg tccgggacct atggattctt caaggaccat gcgctcaaaa
    28081 acggagactt caaagatcaa gtgaaggagc agccgggatc tgcctctgtc gtgcagggta
    28141 tcagcgagga ccggtatggc atcggctata gcggcatcgg gtatagcacg tccggggtga
    28201 aaatggtgcc gctcgcagcg aaggcggggc aaccgtacat tgagccgacg caggcgaaca
    28261 cgaagaacgg aacctatccg ttgtggcggt acctctacat ttatgtgaac caggcgccgg
    28321 gaaaaccgct ctcccctatc gtcaaggagt ttctggccta cgtatacagc aaggaaggcc
    28381 agtccgacgt gttacgagac ggctacttcc ctgtcgatgc gaaattggct gaacagcaac
    28441 tcggcaagat tcggtaatga tcacgaatcc tttgagctat ctctccgggc cggtccactt
    28501 gcggtcagtg atcgaccggc tcgcccgtgg catcattaca gtgggcgggc tggcgaccat
    28561 cgtcagcatt ctcggcatct tcttttttct ctttcgcgag gtcacgccgc ttttcaccgc
    28621 gccgagtgca aagttaagcc aacgcttgag cgtgccggcc ttgctggcag acgaaggccc
    28681 cgcgcaggtg gcggtggatg agcatcgaga gatcgcgcag gtcttcacgt ccggtgcgat
    28741 tcaatttttt gatctggcct ccggccagcc catcgcactg gaaatgccgg ctcagctgac
    28801 ttcgaggcaa gtgacggcca tggcctccgg cggcggcccc actgcgcgtc tggccgtagg
    28861 gaccgcagcc ggcgaaatct tgctgttgaa gatcggcacc acgacggagt tttccgatca
    28921 gggcgaacgg cggaaacggc ctcacgttcg cgccggcgcg cccattccgg taacggatag
    28981 ccccattgtt cgtctggcct atcgctccaa tgatcatggc agtctccttg cgctcgctac
    29041 caagacggga cgtctcttcc tcgccagaat tgctccggac gatccaacag gagcaggtgt
    29101 aatggtcacg gaactgccgc aaccgtcggg tggcgtcgcg tctctggcgc tggaagcatc
    29161 acttgatcat ctgtatgtgg gcacaaccga tgggcacatc atccatgtgg gtgtgtcaga
    29221 gacgcagccg ccggatgtca gggcgtcgta tgcggtcgcc ggacccacta cggcgatcag
    29281 tatgctggga tttctcagtg gagatcgcag tctggtggtg atggcggctg acggggccgt
    29341 gtcgacgtgg ggcctggtgc ggcgatccga tgtgcccacg ggatggacgc tcactcagat
    29401 gcataccttc cgttcccatg cggctccggt gaccgcgttt gccccgtctc aacgggtcaa
    29461 aggctttgtc acgggcgata caaaagggaa tgtgttcctt caccatgcga cctcttcgca
    29521 aacgctgttg cgagtggcca acggcgagtt tccgattcgt gccgtggcct ttgctcccaa
    29581 aggcgatggg gtgattgcct tggatggagc cggacagctg tcgctctatc aggtacaaaa
    29641 cccctatccg gaagtgacgc tggacactct cttcggcaag gtttggtacg aagggtacgg
    29701 tcaaccagcc tatgtctggc aatcgtcctc cggatcggac gaggtagagc cgaaactggg
    29761 gctgctgccc ttggccttcg ggactctcaa gggaacgata tacgcgctgt ttcttgccgt
    29821 ccctatcgcc attttcgcgg ccatctgtac ctcacagttc atgcatcacg accttcgcgc
    29881 gaaagttaaa ccgattattg aagtcatggc ggccttgccg accgtggtcc tggggtttct
    29941 ggccgggctc tggttagctc ccctgctcga acggatgctt cccgcgcttg ccggcatggt
    30001 gttggttttg cccgtgctgg tcatcgtggc gtccttctct tggcatctct gccccatgtc
    30061 tatcaaacgg catttctccc ctgggaatga agccctgctg ttaatgccca ttctggctct
    30121 cgggatcggc gggtgtctgt gggcccattc attttttgaa gtctggtggt ttgacggcaa
    30181 catcaaaacc tggctttcta gtcggctcgg tatccaatat gatcagcgta acgccttggt
    30241 cgtcggcatc gtgatgggat ttgccatcgt gccggtgatc tacagcatcg ccgaagaggc
    30301 cctctccaac gtgccgaaat ctcaaattgc cgggtctctg gcgttgggtg ccacgcgttg
    30361 gcaaaccgtg ttgcacctgg tgttgttatc ggccagcccg ggaatctttt ccggcgtgat
    30421 gatcggtttc ggccgcgcta ttggagaaac catgatcgtc ctcatggcca caggaaatac
    30481 tccgatcctg gactggaact gggccaacgg gttccggaca ttgtcggcca acatcgccgt
    30541 ggaaatcccc gaggcgccgc acggcggaag tctgtaccgg gtcttgttcc tggccgcgct
    30601 actcctgttc attgtcacgt ttgtcattaa ttcgctcgcc gaactggttc gccagcgact
    30661 ccgggacaaa tatagccatg ggtaagccat ctctgcgcat gaaggagttt tggcgaggcg
    30721 gagaactctt cgtctggatg acggcatccg gcgtggccat cagcttgctg atggtggccg
    30781 ggatgctggt cctcattatg ttcaacggcc tggggcagtt ttggcccggc accttgcaac
    30841 aggtgacgct gaagacgcag gagacggtga tcggacacct cgtcggcgag gaaacgattc
    30901 cccattcgat gacgactgat gcgctactgg ggcaacggcg ctttcgttat cgcgtcggca
    30961 atcgggatca attcggttcc gaataccggt ggatcaatga atccgagatc gcctcgatat
    31021 ctgcgcccga cgatctggtg ttcgtggagc gtcgtgaatg gggccctgcc tacggccgta
    31081 tcagcctcgc agcagaaagc actgcggcaa ccaacgccga tggcagcgcc tggagcacca
    31141 tcgaaacgct cgtggaccgc gccaaccagt tgcgccagcg gatcgaacat ctcgagcggg
    31201 aggacatcgg gtcgattaac tatcgtatcg aaaaggccag gcttgcgcgc cagactctgg
    31261 tgttgaaagg tgcacataac cccgccagca ttgaagcaga ccggcgtctc gtcgaacaga
    31321 tcgccgcgct tgaacgtgaa tacctttcaa agaccgacgc actggagcaa ttgcataaag
    31381 aggcaaccca ggaggtcgtg ctcctcaccc tctccaccgg acgatcggtg cgcctctcgc
    31441 tcgatcaggt cttggctgtc agccggccga atgcgatgaa tgggttcgaa aaggctgtgg
    31501 cctatgtccg gaacctttgg cattttgtct ccggcgaacc tcgcgaagcc aatacggagg
    31561 gcgggatctt tcctgccatc ttcgggacgg tgctgatggt gtttttgatg accttggccg
    31621 tgatgccttt cggggtgatg gcggcggtgt acttacgaga gtatgcgaaa caaggaccgc
    31681 tcgtcaggct ggtcagaatt gcggtgaaca acctggcggg agtgccctcg attgtgttcg
    31741 gcgtgttcgg gttggccttc tttgtctatg cgctgggggg aactatcgat cagatcctct
    31801 ttcctgaatc cttgccgaat cccacgttcg ggacgggcgg gattctctgg gcttcgctga
    31861 ctctcgcact gctcaccgtt cctgtcgtga tcgtcgccac ggaagaaggc ctctccgcgg
    31921 tgccgcgcga ttttcgggaa ggatccgtgg ggttgggggc caccaaattt gagacgatcc
    31981 ggcatgtcat tctgccttgc gccttgcccg gaattttgac gggattgatt ctcgctatgg
    32041 ccagagccgc aggcgaagtg gcgccgctga tgcttaccgg cgtggtgaag ctggccccgg
    32101 cgcttccgct ggacgagtat cttcccttcc tgcatctcga acgcaaattc atgcacttgg
    32161 gttttcatat ttatgacgtg gggtttcagt cgccgaatgt cgaagcggcc aagcccatgg
    32221 tctacatgac caccctcatt ctgattcttg tggtggtgct gttgaatctg gctgcggtga
    32281 tgttgcgcaa ccgcttacgc aagcgattcg cgacctcggc agtgtgatca cagagaggag
    32341 ttcccatgga agttcaatca gacaggatga cggtgacggc gccaaaggtt tctttacgcc
    32401 ccgccatctc cccctcccgg ctcgcgtcgc ctcaacgggc tttcgggtcg ccggtgcaga
    32461 caaaaatatc agtgcgcgat ctggattttt attacggaca tcggcaggcg ctgtttcatg
    32521 tggggttgac gatccggagc cattcggtca cggccttcat cggcccttcc ggttgtggaa
    32581 agtccacgtt gctccggtgc ttgaatcgca tgaacgatct ggtggaggga gcccgtccgg
    32641 taggccgtgt ggaattggac ggcatggata tctacgatcc ggccatcgat gtcaccgatt
    32701 tgcggaagcg cgtcgggatg gtgtttcaaa aatccaatcc ctttcccaaa tccatctacg
    32761 acaacgtggc ctacggtccg cgtctgcatg ggatcaaaga taaacggtcg ctcgacgaac
    32821 gggtccaaca cagtttgcaa ggcgcaggcc tttgggatga ggtgaaggat cgccttcagc
    32881 acagtgccgt gggactttca ggcggccagc agcaacggct gtgtatcgcc cgtgccctgg
    32941 cggtgcaacc ggaagtgatc ctcatggatg agccctgctc cgcgctggat cctatcgcga
    33001 cagggaaaat cgaagagctc atctatagct tgaaggagac ctacaccgtc gtcatcgtga
    33061 cgcataatat gcaacaggcg gcacgggtct ctgaccagtg cggatttttt ctgatgggcg
    33121 agttagtcga gttcggtgac accaaaacca ttttcaccac gcctcgtgac aaacgaaccg
    33181 aagactacat cacgggacga ttcggataaa tcgcgagagg agcctgaact atgcaacgac
    33241 acttcgatca agacctcgcg catctcaaac agcagctgct ccgcatgggc ggcctggtcg
    33301 agtcgcaaat ccagcaggcc ttgcaggccc tggtggaccg agattccgat ctcgccgtcg
    33361 atgtcatcaa gcaggatcac gacgtgaacg gattggatgt cgagatcgac gaactctgcg
    33421 tacagttgtt agcccttcaa cagcccacgg cccgtgacct caggttcgtc accaccggca
    33481 tgaagatttc ttccgagctg gaacggatgg gtgacctggc cgacaatatc gcgcagcggg
    33541 cgttggagct gaacagcgaa ccgcagctca agccatacat cgacattccg cgcatggcga
    33601 attggaccat gcgcatggtt aaggagtgcc tggatgcctt cgtgaattcc gatccggtct
    33661 tggcgaggaa agtctgcacg gacgacgatt ttgtcgatga ggtgaacgaa cagttgtttc
    33721 gagagttgct ctcctttatg ctggaggaca cgcgtaccat tacacgcgcg atccgtctga
    33781 cgtttgtggc aaaatcgctc gagcgaattg ccgatcatgc cactaacatc gcggaacttg
    33841 tcgtctatat ggttgaaggc aagaacatcc ggcacgtcgc tcctaccgcg agtttctaga
    33901 tgcccaaact ggccgtcctc gacatcggca ccaattccat ccatatggtg ttggccgaag
    33961 ttcagccgga ttactcctat aaaatcctcg atcgtttcaa agacatgacg cgtctgggcg
    34021 acggggtgtt cacctcccgg cgtctttccg accaggccat gatgcgcgga ttggaagtga
    34081 tccgcacact cgtgaatctt gcccgcaata aagggtacga acagatcgaa ggtgtagcca
    34141 ccagcgccgt gcgggaggcg aggaacggcg gcgaattcct agatcatgtc atgcagcaaa
    34201 ccggcctgac tgtgcgagtg attaccggcg cggaagaagc ccggttgatt ttcctcggcg
    34261 tgcagaacag cgtggccctg cccgagtcgc ccacgctggt gatcgatatc ggcggggggt
    34321 cggtggaggt catcgtcggg aatcgcgagg ccatttttca ggcccggagc ctgaagctgg
    34381 gcgcaattcg cttaaaggat ctctacctct ctaaaacgcc tccatcaaaa gcgatgcttc
    34441 gggatctgga agcggcggtg accgctcaac tcaagaatgc cttgggctcg tacaaaacca
    34501 aacgggtgga gcagattatc gcgacgtccg gcatggcggg caacctggct gaggtgattc
    34561 atctgcaacg caccggccgg ccgcttccgc agctcaatct ggccagggta tccgccaagg
    34621 acatcgccgc cgttgaaaaa cgacttgccg gcgcttcgtt gaaaacgcgt ctggccatgc
    34681 cggggctgga tcccaaacgt gtggacaccc tgcttccggc cgccatagtg tttaggatct
    34741 tgctggagct gttgcagaaa acggagctca ccctctgcga caaagcgatc cgcgaaggga
    34801 ttatttacga tttcattcag cggcaccacg accgtatcca agcggagcga gacattcccg
    34861 acgtgcgtaa acgcaacatc ctggccctcg cccatcgatg ccatgtctcc gaaacgcatg
    34921 cgttgcatgt ggcgggattg gccttacgtc tatttgatca gacgaaggcg ttacatggac
    34981 tcggacagcg ggaacgcgag tggttggaag gtgccgcgat tctgcatgat atcggctata
    35041 tgatcaattc gcgacagcat cacaagcatg cctactacct gatcaagaat agcgatctct
    35101 cggggtttac cgctgaggaa atcgatttga ttgcgaatat cgcccgctat catcgccgtt
    35161 ccgttcctac caggaagcat gacgaattta cggtattgcc ggagggctcc cagcgagtca
    35221 tcaatgtctt gtcggcattg ctgcgcattg ccgatggctt agaccgaagc cagttttcgg
    35281 tggtgcagaa tatcgacgtc aaactcggca agaccgtggt gattactgcg caggtgtcgg
    35341 gtgatgcgga gttagagatt tgggcggcgc gaggccggag cgatctgttt gagaaagtct
    35401 tcaagcggcc ggtgcagttc ataacgacca cccgagacga cgatgccacc tgaatcggga
    35461 tccacggtca actcctacag gcactcctta ctgcacgaac ttactttcga agccgcgtgt
    35521 attctaagcg agggcgctca gcagtgaatc atcgaatggc gacgcttgcg cgagcacctt
    35581 acgccagtgc gcgcaattgt gacgcggtga gccaccactc caggcggcct tttgcgggac
    35641 gcacggaccc ttcaagatga agtaggcacg cgcctgcttt tttgagcgaa agccctttgc
    35701 acagctttcc cgtgaggagg attccagccg tcgcgctcag gtgtggttcg tgccccacgc
    35761 agaggaccac ggcgtcggac gggagtgtgt tgagcagtgc aatcaatgca cgcggaggga
    35821 cttctggatt gagttcctgg cagatccgca gcggcggcgt tgcaggaatc aacgatctcg
    35881 caatcttggc cgtttgctgg gcgcgtgtca gggggcttga aaggataagc gtcgggatac
    35941 agcctagagt cagcaatcct ttacttgatt gccgcgtccg aaccaggcct ttatccgtga
    36001 gtggccggtt gtgctcgttc ccccgccagt cctcacgatc gtaggcaatg ccgtgtcgaa
    36061 ataagagaca atccatcaac gtactccctt gggatggacg caaggtggtc gggccggcca
    36121 taattcatgc aatgggtgat cttccgtgag ccccatcgca caggaattga ttattcgtca
    36181 tgggtgacat gctccattct attcatacag gaccgcagtc accgactcaa gggttgctca
    36241 cgatggcggc ttccagtcac gccaccgttc tccatttgtt gcgccaagcg attgcgggaa
    36301 gagaacatgt ggacacgata cacgccatcc gtacgcattg ccgaagactt caagctttgc
    36361 tggaactcta cggcgaggcg aaacgtgctc gtgcagtggc agcttgtgtg aggcggttga
    36421 gcaaactgcg agcgctccag gtgttcaggc agtacgtgat caggtgtcac gccgggcgaa
    36481 aagatgtggc cgtggtggat gaccggctga cgaaacagat caggaagttg aatcacacgg
    36541 aggcctatcg caggatcgaa caggttgtct cgaagcaggc gcttcccgcg atcctctccc
    36601 ctcctcagtc ctggaatcgc cggcttgatg aactgcgtca ggagcatgaa tgcgcgctca
    36661 aacggctcat cgcggctgca tcggacaagc ctcggcggaa acgcctccac gcgttgcgtc
    36721 tcgccttgaa gacgatccgg tatcagactg aatggttgcc cggtcgaaca gcagcgaaag
    36781 aagagatgct ttcccaactc aagcgggttc aatctttatt gggaaaatat gaggagctgg
    36841 cagattttca tcgttggggt aagaagctga gtcttccggt gcggaagcgc atgaagaagg
    36901 actggaagcg agcgagaaaa cgagcccggc atgtccccgg aacgatgtcg tggttactgg
    36961 atgcgttggc atccgggcat gtgtggagcg gcgaaaatct tcacgtggca tcagtgaacc
    37021 gcaggtccgc ctgagtcgtc cgaggctggt gtcgagaggc gaaaacctcc cggcacgatt
    37081 ttgatggact ccaccaatgg ggcatcttgc gacagctttc ggttgagctg ttgcatgcat
    37141 cgatcgagtt ctccgtcgtg catgaggctg tcgtctcccc agagcagaga tttgagttcc
    37201 tcgcgcggaa caacgttccc gacggtactc gccaatcgac gcagcgcttt ccactcgtgc
    37261 gcggataacg tcaggctctt tcctcgatag accgcaacat acaaattttc agtcaaggcg
    37321 agatcttcag ggagttcttc atcctgcgcc tggctctgcc ggcaacgacg caacagtgcg
    37381 cgtacgcgag cgagcagttc catcccggaa tagggcttga cgatgaagtc gtcggcccct
    37441 gcgtcgaggg cttctgcccg gcgctcttcg gacgaaaacc cggacatgac aatgatggga
    37501 atgtgtgtgg tggaagggtc ctgccgtaag cgcttgcaca tctcccggcc ggtcaatccg
    37561 ggaaggttgt catcggccac gattaaggag ggtttgatcc gccagacatc ctgcataccg
    37621 gccggcccat cgaatgccac gttggtgcgg tatgacgcct gccggaggat ttgatccaat
    37681 aatttagcct gactctggtc atcttcgaca atttcaatga tttctaaagc catgcggaca
    37741 ctcccctgca cttatcatcg gttggtaccg aatgaaactt gaacgcggtg gtagcaggca
    37801 gaaatgtcag gagtgttgct ggctacttgg aggcgccgag aatacgctgc agttgggtca
    37861 cccaggagga tccgtcgctg cttgccgctt cattgcgagt ggatcggatg gggcggccgt
    37921 ggagccgctc gagccgttcc gccacgtcct tgaagctggg ctcttctcgg ccgatccagc
    37981 ggtattgctc aagcgcatca tctgtgcgct ctaacgactc aagggtgcgc gccaacagat
    38041 accgaacctg gatagtatca ggggatgccg agcgctttgc ctgtaatgac tttcgaaatg
    38101 ccgtaacggc ctcttccggt tgcgcgaggg atttcaagca aatcccaacc tgcgccattg
    38161 ctttaaaggt gaaggcggca tcctgggcgg cgagagaaaa cgcttgtaag gcttccttat
    38221 acgatccggc tttcttgagc gacagtcccc gctcgtactg ttcattggtg tctggtcgtg
    38281 ctgtagccac acctgaagaa gtcgggactg catcatcacg gcgcggaact tcattggacg
    38341 tggatgcggc tcgagctgac agtgccgcca gttcggtttg ttcggcagcc tgttgatcag
    38401 gcgtcactgc cgtgagggat tcagtgttcg acagcggaag aatgccccct ttggtccggt
    38461 ctttcgcggc ttgcgccacg atccgcgccg acagaaatgg cgcttcctcg gcgaagccat
    38521 acgtcagggc cgtatcgcac agttggttga tcaagcgagg aatgccgccg gtcagccgat
    38581 gaatcgtccg cgcggcctca tgtgtgaaga gcggctcttc tcgccccgcg actcgcaaac
    38641 gatgggcaat gtatccgatg ctatcttctt ctttgaacgg ttcaagactg taatccacca
    38701 tcacacgttg cgcgaattgg gtcagatctt tccgttgcag cagctgtcga aggtccggtt
    38761 gtcctgacaa aatgatctgg aggatgggcg ccttatcctt gttgagattg gagagcagcc
    38821 gcaactcttc cagtagattt gctccgagat tctgcgcctc atcgacgatc aacaagaccc
    38881 ggcgtttagc cgccgcttct ttgccgagga attgctggaa cgcatgaaac ccttccagct
    38941 tgtccaggtt tttatcgttc tggccgaagg cgagtaaaat ccacggcaag agagtttcca
    39001 tgccctcatg cgtattggtg atgagccccg tggtgaaatg gttccgatgt tcggccagga
    39061 tttgctgaat aagtgtggtc ttccccatcc cgggctctcc ggtgagcacc acgaaccccg
    39121 cgtgattgag gatgccgtat tcgagggtgg tgagcgcgag gcgatgggtc tccccgcgat
    39181 agagaaaatc gggattcggg acgagagtaa aaggcttgac cgtcaggtga tagaagcgtt
    39241 cgtacatgga tcttctttac gagagtaagg tgtttaggtc aataacattc gcttcattgc
    39301 cgccggggtc atgtggcctt tgccggcttt gttaagcacg gtgcccaata ccggtgtgct
    39361 gcctttgact aattgcaggg ctcgctcgac ctcttcacgg gtggtcttcc cgtcctcgac
    39421 gacaaggagc aaggcgtcgg tgtagggcga aaaggccaac acatcggcgg tctgcagcag
    39481 cggtggcaaa tcaaacagta cgatgcggga tggataccgg tgcttgaact cctcgacgag
    39541 cgaggccatc ttgggcgagg tcaatgcttc cgttgaattc gtaatagatc ggccggccgg
    39601 cataagcaca aaccgtccga ttccgggatg aatcaacagg tgctcaacgg gtattccatc
    39661 cagcaaataa tcgaccagcc ctccacactc ctcaattcca aatgccagat gagcgctggg
    39721 attggtcagg tcggcatcta ccaacaggac cgtttgtgtc gtatccatgg cgaggctgat
    39781 ggccagattc accgcagtca gcgttttgcc ttcttgtttg ctcgggctgg tgatgcccag
    39841 cacgttccaa ccatgttcgc gcagtcggtg catgacttgg gtgcggagaa ttttatacgc
    39901 atcaagaaag gggccgcgct cgaaaccggc aaggactcgt cgttcacgca ggacgtcgtc
    39961 cgggatgtcg acggtgcggg tgtgcgtata cacaatatcc tgcacagcat cttttccgat
    40021 tcgagggggc ggtgctttga gaacgaccgg cgtggggcgt cgctgttcct cccgcttgaa
    40081 tcgttccatt gcactgtgta gcggttccat gtgaaatctc ctactcggtt aatcgagacc
    40141 gaatttacgt agcgcggcga accacaccac atcgagcggt agccagaaga aatgtgccaa
    40201 taaaatgcag gcagccgcga tgccgatgcc ggcaaggcgg atggttcgac gcttggcaat
    40261 cagttggcga aggtccgcgt tattgggaat gtagggaatc acggcaagtg gataggtctg
    40321 ggtgatatga gccagtgatt ccgggccgcg gattgaacgg tcgacgtttt ccagtaagac
    40381 cccgctgccc gctcctcctg ccaaagccag cacaaaactc aggagcagga taagtggacg
    40441 attcggcttt tccggttttt cgggaaggtc cggcggatca atcagggaaa accgttcacc
    40501 tttgcgctgt gtctcgagcc cttcggaaac ttgtgcctca agaagtttgg aacgcaattc
    40561 ttcatatttc cgggcggagt tgtcccgctc ccgcgcgagg tctaagtact ccggttcgaa
    40621 atggtgagtt ttttcgagac gccgggcata gtcttccgca cgtttccgca atttggctcg
    40681 ttgcgctttc agcgcttcca acatcgaagt ggccgaagct aattgcgttt gggtgttgat
    40741 gtacgcgggg ttctccggtt tgatggctgg catcttggcc ggtgcatttt catattcccg
    40801 aaggtctttc tccaaagagg aaatggtccg tctggacctc gttacgtccg ggtgatcctc
    40861 cccgtatttg tcgagtagag ttgctaaggt agctcgttca ccggtgagac gtttcagcac
    40921 atcgtcgatg ggagccgctc cgcccgtctc tctctccagc gctcgaatct cttgctgcat
    40981 tttccaaata tccggatgct caggcgagag ataccccgct ttatcagcat attccgcgcg
    41041 caaggctttc agccgctcgc ccgagtccaa aattctttct ccagtcgacg agagaatcgg
    41101 cgtgttaggt ttaatggtgg cgagttcacc ttcgagaaac gtctttcgct cctccaaact
    41161 gcgaatgtcc cgatcagtat cggtcagttc gcgctcggca ccattcaaga gttgcatatt
    41221 taattgtgtc agttcaggaa gtgcgccatc tgcacgctgt ttgacgatag agagtttctt
    41281 ttcaatctcc tcaatgtgac gggagagacc atcggcttcc tgcttgagga aggcggtcgt
    41341 ttcctgggca tgccgttcgc gagttttcag gttttccgcc agaaataaac tggtcagttc
    41401 attggcgacc ttttgcgctg attcaggact ctctccgtca tacgatagtg tgaaagcgat
    41461 ggtggcttgg gtgggattct gagtccgttt gtcgacgact ttcgcattga tgacatcgat
    41521 attcgtatct tttgtaaacc gatgaagcac ttcttcggtc ggactctgct tccgcatgtg
    41581 tttgtacaag tcgtactgct ccacgatttt ccacaatgtg ctgcggctca tgacttgttg
    41641 cttaatggtt tcgattcgtt gatccgcgta cgtagtaatg gcggaacgca cgagatccga
    41701 ggggatttcc tgttcttcaa tcaggatggt cgccgtggag cgatagaccg ctggaatggt
    41761 gaatgcgagg gtggcaccca ggaggagaat gccgagggtg atcatgatga tgggcatctt
    41821 acgtcgcttc gccatcgaaa tgatgtcttg gatgccgacc gttggcttat tcatggtccc
    41881 ctgccacttt ccgatccagt ggatctctct accgtcctac cgtaaacctt ggagggtaat
    41941 acgtaaacat aatagttgca gaattgccca gtgcggtcaa cgattggctg ggaaggtctc
    42001 gttgggcata cgtataggta atgtccgccg tccaccattc cgacagccgc cagctgagct
    42061 tcggtgtcac ataaaagagc cggttctcag ggaacacggt ggaaacggcc ctggttttca
    42121 ccccatcggc gatgagaaac aagccggtga ccgaagccga caggcgatcc gtcatttgat
    42181 gggacacttc caggcttagt ttatcggtac ggagcagcag gccgaatccg ctcgggttaa
    42241 tttctcttcc gatctcacct ttcacccgcc agtcttccca tcgtctttcc aagttccctg
    42301 aaaagaccca ggtccacaca ccatcggata aagacccggc ggaagtgttg atggtggacg
    42361 acacatgcct tggtcctccc gatacagttc ccgtcaaggt ttcagaaaac atgtgtgaat
    42421 aggtgatctg agggccgata atcgttgaac taagccgaag atctgcggca ttgaaacgca
    42481 cgcccacagc attcagctgt acctgatcgc gctcaccaac ctggtatgtc atgcccgtcg
    42541 acccaacatg caaggtatag tctgccaatc cgaggcgcag gccgttctca tagcgcgtgt
    42601 cgtaaaacgt gtaagagccc gttgcggaga gccgttcggt aatggcatgc gtccatgacg
    42661 ggttgagtat ccactgattc cgctgagtga aactgagcac cacgcctgtc tgtcgcagtt
    42721 cgcccatgag ggtattatcg cgtgtgaatc cgccatcaaa accgaagctg tcacgctcca
    42781 ttttgtactt ggcggaaagc gggaaataca gattcgtaag gctggtattc tgccctccat
    42841 agtatcgaac aaaatccgcc gccaatcgtc cgttgacctc cagcgcttcc gttgagcccc
    42901 cgaacttggc accgggggat acccaatgac catacgtcgt cttatggtcg aacgtggtga
    42961 gagtcaggtt actattgacc tccccgcgca ccgtcaaggc cggttccaaa aaccattctg
    43021 cagaccagac ctcctgatcg aggctatgac tcgaccacgc ggtcgtcaaa agaatggccc
    43081 ataaccaggc tgttggaata agacgatgct tcaccgcgac acgttcgcga tgccgatcga
    43141 gtttcgatga tgcatcacgg caccatcacc acatcccccc gctcaaggag gatgttttga
    43201 ttgaggtctc tgcctttttg aacgtcgccg tatcggaaca ggaagacgcg ttggtcaccg
    43261 ttttcccggc ggataatctt aatgtcattc tccgatgcaa acggcgtaag accgccggca
    43321 aggctcaggg cctgtagaac gtcggtatag tgtcccacga ggtattcgcc cggcttcgtg
    43381 acccgaccca tgacatacac tttgtagctc tggagttttg tgattgccac ggagacatgc
    43441 ggattaggaa taaaccgggc taagcgtttg gcaatgtcct gacgcacctc ttcaacggta
    43501 tgtcccatag ccggcacatc cccgatgagc ggaaacgaca ccatgccatc tggacgaacg
    43561 atcgcctctc gtgtgagatt ttcgtctttc cacacggaga tcatgacgac atcttccggc
    43621 ccgagatggt atcccggatc ggccatgttt tgagcggcag tgtgttcggg cgtgacacag
    43681 ccagtcatca gcacaacagc gtagagcgca agcaaacctg gctggcaacc tcgggctagt
    43741 ttcttgatca gtaacgaacc ggcaatcttc accctctttc ctcctatcct gtaacttccg
    43801 caaggaccga tttggcttcg tccatgccgg gaaacggttg tttcgtgttg agtgcttttt
    43861 tgagatgggt ttgggcttcc acccggtggc cggctttgaa gtgagccatg cccaagtgat
    43921 aattgagaat gggatgttgc ggggcctctg taaccgcacg ttgaatcaca cggatggcat
    43981 catcctgatg tcccattttt aggtggaccc accccagtgt gtcgagaaaa aatggatttg
    44041 gtgcgcgctg ctcaaactcg cggctcaacg ccagcgcccg atccaggctc ttcgcatcac
    44101 ctttctgatc ggccagaatc gaagcgaggt tgttggccgc catcagttgc ctggggttgt
    44161 gtttcagaat cgtttcatac tccaggatgg cctgatcgaa ctgcccacgc tcacccaggt
    44221 gcgaggcata gaggaggcgg agttcctcgc tggcggggtt gatctgcaat ccgcgttgaa
    44281 gaatgtcgcc tgcttcctcg tgtttcctct gagagagttt gagcgtgacc cagttgaccc
    44341 aaggagtgcc ccactccggc ttgagggtag tggcaagccg aaattcttgt tccgcccgca
    44401 tcggatcgcc tttgaggata agaatttctc ccagtaggcc atgcgcgaat ggatgctgtg
    44461 cgttttttgc gatgaggcca ctgaggcgat tgtgagcttg agccaacttg cctaaccgtg
    44521 catcgatgcg gaccaatgca aagatcggtt ccggcgcgtc aggattcagg gaagaagccc
    44581 gttcaaaggc cgccacagct ttatcccatt gcaagcgggc ctgatataga ttgccctcgg
    44641 cgagatccgc tacaaaccgg ttggcaccgg cctcgcgaat gcgtgataag gtctggtcgg
    44701 atccatccca atcacggtcg gctgcctgca gattcaacag catgcccaat gttccgagat
    44761 tcgtcggcgc ctgtttgagc aattcttcca ggcgcactcg ggcgtccctt gtccgtccgg
    44821 acgaggcatc aagaatggcc agtgccaggt gcgcctgata gagattcgga ctgagtgtta
    44881 cggctctttc aaggttctca cgggctaagc ttgtttcctc caacattaaa tgagcctgtc
    44941 ctagcaacgc gtaagcttct gattgttccg gctggtcttt gagcacggtg cgaaaggctt
    45001 gaaccgcctc tcgagcggaa ccatgttgaa gcgcaatccg cccttctagc atgagcgcat
    45061 ccgacgcacg cggattatcg cgaagcactt cacgcagctg ttgcatggcg tcgtcctgtt
    45121 ttcccgcagc ccaatcgagc gtggccagct ttatctttgc attccctccc gccggtttag
    45181 accgattgtg atcgcggatg tcctcgtagg tcgcgcgtgc cttgtcaggc agttgatgca
    45241 attcatacaa acgtcccagt gcaaattgaa tattcaccgc atgaggaagt acccgatggg
    45301 cttcgttgag agcggcttcc gctgtctcca cattttttcg acctgccaga taatcggcga
    45361 gcgcgagatg tcgctgttcg ttgtcctgat cgagacgcag cgcttcgcgc aagatcgctt
    45421 cggccttgtc atattgccgt tgctggtcga aaaagagtgc gagtttgagg tgatgatcga
    45481 agacgctggg ttcgagagcc agaatgtcac ggaacaccga ttccgcttgt gcctgattgc
    45541 ctgcacgcat atacgccatg gctaacgaat tcagcagatc aaggtcatgc ggatgggctg
    45601 ccacagcttt tcggagaacg gcttcgaccc gctgaggcga gttctgaagc gcatacaatg
    45661 tgctcaacag gatggctgca tccggttcgg ttggaaattg cttaaagaga gcctcgccgg
    45721 caaccaccgc ttgggtaagt ttgccgtcag cggcaagaag cgctgctttg atggcttgcg
    45781 cggagacgtg tcctgggtat acccgaagca ggtgatcggc cgtttcatgt gccttctcat
    45841 ccaagcggcc ttgcaaataa aatttgccta atttgacgag tgcacgctcg tgatccggct
    45901 caagctcaat cacccgctgg tagtgcgcaa acgcgtttcg ccagttcttc tccttctcct
    45961 cgacctgcgc atagagaaaa taggcttccg aatcttttgg atcgattttt aagacattcc
    46021 gaagtgcaac gcgggctttc ggaaaattcc ctgcctggag atattcttgc gctttggtgc
    46081 ggtacttcgc tttgcgttct tcgggccctc cacagccaac cgcaagaatc agcactatgg
    46141 ccaagccgaa tctcgcgatt gtgtgacatc gatgccatgt cgtagccata gtgtcttgct
    46201 tccttgttat atccaggctc gcacggcgat gccgcacagc agccagagag cgaccaatgc
    46261 cagttgagtc agccggcggg cgaatacgtg gaggaggagt tcaaaagaaa agaatagtac
    46321 gatcaatttt gccgtcagga agctcaaatg tatgtcgccc atctgcattt ccggcaatgc
    46381 ggggaccatg atcgcgagaa acaccattag atagtctaag ggcgtcgttt gaaaccgatg
    46441 ttcagagttg aaacggatgg tgagagccac cagcacggcg aggcccacaa agaagatatg
    46501 gatggggctg agaatgtccg tggaagaagc gggctgctca ctgagataca taatgaacgt
    46561 acttccgaca tagagtccgc cccggacgac cagcgatgaa atcctgggag aggcccacag
    46621 tccgatcagc atcacggcaa acatcaccgc ggcgacatag cccatatcgt ccggaacgtg
    46681 tttgggcaaa aagacgctga gaattaaaaa cgccggcacg gcaattccga gaatctggat
    46741 cggttcagtc gtcagccagg gcgaagaggt aatggtgctg gctcgagtca ggagacggtc
    46801 ggccgtcttc agcatccgat tcgattgaat cttccaggag cgggagcgta agaacggata
    46861 caaaatcatg gtcgccacga ggccataggt gcttaggatg gccaattcac tctgccagcg
    46921 cagaatatag gccagcgtga cgagagccgc ctgcagaaga taaatcatca ggacggcctc
    46981 atagtgggag agccccatgg cgagcaattt gtggtgcaaa tgatttttgt ccgcgacaaa
    47041 cggcgaccgt ccttccttca gccgttgcaa catgactccg acggtgtcga gtagcggaag
    47101 gccaagaagg aacaggccca gggctggcgt atagggaccg cgttgcggat cggtcaagac
    47161 gatcgcagag accgccataa aaaatcccaa aaactggctt ccggcatctc ccatgaagat
    47221 ccgcgccggg taggtattga agcgtaaaaa tcccagcaat cctcccagga ccggaaccat
    47281 gagcagtgtg acggtttgat ctcctcccag gtacgctagg caggccatgc ctgcgaagct
    47341 caacaacgac aagccgccgg cgagcccgtc caatccatcg gcaagattca cggcgttcgt
    47401 caccccgaca atgatcagcg tcgtcaaggg ataggcgacc cacaggggga gttccgtttc
    47461 gacaaatggc agcgagttga ggtgaatatt gccctgccac atgatgatga gcgcgccgag
    47521 agtttgccca agaaatttga tcgtatacgg caagccaacc cggtcatccc acataccaaa
    47581 cagcagaatg gtgactccgc cgagaagtcc ggccaccaca atgtcgtcct ttggcgccca
    47641 gatcagcatt gcggaaaacg tgccgacccc gaaggcgatt cccccaacct tggccacggg
    47701 gatggcatgc acccggcgct gatctttcgg aatatccaga aattggaggc ggctggcagt
    47761 cgccatcaat ggcgggatga gcgccatgca gatgatcagc gaaccgacaa agctgaaaaa
    47821 taatgtggaa atcatgctgt gctatctgct cagtctagtc gggaacatac cgggtcaaga
    47881 tcggattcat gtcttgagcg aagtgcagga gccgctgttc tgccgcgccc tcgctttcat
    47941 tctgttggat cggggtggtc aatcgtatca atgcgccgtc ggtccgctgt cgtgtcatgg
    48001 catcccacag gacgtacagt ttcaccaggt attcgttcgc cacgatgcga tggcgttgtt
    48061 taaaccaata cagcaccagt tggcgctgat cacctttctg gatcgaaaca cgattggcgg
    48121 gtgcctgccc tgcggccgag tcaagctgca ccgtctcaat cgtgccgatt tcccaccctc
    48181 ccccgggaat gcaactctgc ggtgaatgag cggactgtcc tttgcgttga gaccgatagt
    48241 aagcaatgta caaattgacc gccgctgatt gaggttgctg atagtcggcc aatacgtagt
    48301 cgtcaaactt cagcacctcg acatagcgcc cttcgagggg aaacggggta ccggaccatc
    48361 ctttgaactg catcggaaaa tccaggaacg gctgccgaac gggcggcacg tctccccgct
    48421 cagtcaattc tgtggcggcg aacggcagca ggcataccag gccgacgcta tacagatacg
    48481 ttgggcggag cagtatggct ctagaaggca gtgatgcagg aggcaccatt tcaggttgag
    48541 gttgagaagg tgtgtctcgt gtgacacgcg tcgcgccgat tttgcgtagg acaaacattt
    48601 cggcgaggag caagcccaga ctcgccatga ataagaccca gccttcaaat gcgtgataga
    48661 acccttctgc cgcaccctgg ccgaaatgtt cgaccagcac accgatcatc ccgatgcgga
    48721 atccgttgag aagaatggaa atgggaatgc tcgatatgaa cagcacgatg cgtttccaca
    48781 agcgttcccg gaagagataa ctgcagagca gtgccagggt cgccagcggg aaaaggtatc
    48841 gcaggccgct gcaggcatcg actacctgga gctgaatggg ccccaaatca atcacattcc
    48901 cgtcccgaaa ggccgtgatg ccgataaatt ggaggcaccc gacgccgagc gcggatgaga
    48961 tgagctgcaa tttccccgag agcccttgat agaggaactg tggcaagggg acgacggtga
    49021 gaagaaatcc caaaggaaag gcaatcgtgg agacggcccg agcccctaat gcagacacta
    49081 acaaccccac aatgatgcac cacaatgcga cgtgcagaaa ctgatagacg gtggcgagtt
    49141 cacccacgac atacagggcg gctccgagca gaatccagat gagaccccac cacgatccgg
    49201 accggctctg ttccatgagg cgtcgtcgtt gttgccagat aaggtacagg ctgatcagag
    49261 gcaccagcat tccgtgcccg taattttcgt cggtgagcca caaatcagcc atgtaggcca
    49321 cgctgtctgt gaagactagg ccgagtatgg tcacgggcag aagcaccgtg aggcccaacg
    49381 caagtgagcg ggtcggtgct gctgcggaga cggaggcaac cggctctgcc aagaagcgag
    49441 ccgttttcgt cgcaagctcg ggagtggatc tcatcctaat actcgttttc gcagaatgtg
    49501 aaacgcgaaa agaggtaaag cggtctgccg tacaaggcgg ctgggttgtg acagcaatcg
    49561 atagaaccat tcaagatgaa tgcaccgaaa aatccatgga gcgcgtttga cccggccggc
    49621 gaggacatcg aaggttcccc caacgccttg gcagaccttc acgcgcaagc gaggaagata
    49681 cgtggacatc cacagttcct gcttgggact gccgagcgcg ataaagagga aatgcggagc
    49741 gacggcatta atatgatcga tgaccgccgg catgtctgcg tcgtcaacat atccgtgctg
    49801 cgttccagca atcgtgagtc ccgggaattc ctgccgaagt ttgtgtgcag cccgttcgtt
    49861 cacttcagga ctggcaccga acagaaagat gctatatccc ttctccgcag ccaaaccgca
    49921 gaggcgtggc atcagttcgg accctggcac tcgttcggca taacctaacc cgaggagttt
    49981 ggtggcgatg acgaccccga ttccatcggg aatcaagagt cccgcagagc gtaaaaattg
    50041 ccgaagcgtg ggatcactct gggctttcat gatcttctca ggattgaccg caatcaccgt
    50101 cttgggttcc gacaatgtca tgcgagagtc ggcccacgcc acagcctggt ccatcgtgac
    50161 gcaatcgact ggaatattta aaatgtcaac gcgtgttgga accatggaag cttctggaca
    50221 acgaaaaagt ttgcagctgc gtcgggggtg gcccctcccc gcaccaaatt cttgtcagga
    50281 actcatgcgg aagcgcaccg cgatattcag ctcgtagtgt ggtaatgggc tcctttgatc
    50341 cataagtcga agagcgccat cccgaaggcg gagcggtttc gccgtgatgg agcgaggcga
    50401 gtcctccttc gacggagatt tgaaccggtt gctcccggca tgccaggacg taggacgcgg
    50461 agttttgaac gggagacact cccagatgcc aattcaattc caagtggtga gtgccggttc
    50521 cggttagcca atcccaaatg agccatgcgc caggtggctg atagaccact cctcgccagt
    50581 gggtgacccc gcatggctgc gtgtagccat aatgtcgcgc cagcaccgta atttttcctt
    50641 caggtgtttc gtcacgatag attaaatggg tttcgaaagg ctgtgaccag agaaaagacg
    50701 tttcctgcgt ggcttgatcc cggccatcga cggtgaccgt attatgggcg cgagtgcttc
    50761 gaaaataacg ccgccactcg gaatggccgg tgtaactgta ggtgccggga tcgatcagaa
    50821 tttcctgttg tccgatctcc aattgcaccg acaaggcatc ggcatggcca tgcgcataac
    50881 agggtgccat gcctaattcc ccgtggtcga acagcagtcg ctcgcctttg ctgccctgca
    50941 gaattgaaca gccggacaga tgaaacgagg tcaagccggg ggctgcctcg gcagaaaccg
    51001 gcacgaactg gaggaatgga gagagcgcat acccactgtc cgcgtccccg atacgtggca
    51061 gggcgccatc gcccggacgc atcatcgcct gaagaaacgt atggcttcgt tcagtggcct
    51121 ggatcagttt ttgaggaatg agttgttcat gctggcgtaa cagggcgacg gtgagtccgt
    51181 acaaatcgga gataaaccgg aggtaccaga tcgcctcttc acgccctcct ccatcctgtc
    51241 taatttggtg aggagcctct tgctctaaga gatagagtcc ataggctaac cagcgttcag
    51301 ccatctccat tttggggaag agaagccctg cgtatacgag gccggccgct tcggcaatcg
    51361 tatgattgcc ggaggaggaa tgtccggaca cgcgtttgcg gatgagctcc gcgtgggtgg
    51421 agacgaggtt caaggttccg gcccagatcg cttctggctg tgacagccat ggcctgacca
    51481 ggtctagcgt gtggcacacc gccatgaggc gaagtgcgca ttccatgact gagatgtaat
    51541 gaatccctgt caatggtggg ttcgcggcga accaggacag gagttgtccc tcgatcatcg
    51601 cgacagcctg tcgacgtttg tccggctctg cctgctgggc atacaaggcc aacgtgagga
    51661 gatgttgaag acgggagggt tcccaggcaa tacgaatatc cccgaacgga ttgccctctc
    51721 gataaggaat gcgatgaaag aaaatctgtg gccatagctg cctggtatcc ggcgcttcat
    51781 gccagacctt cgcatcggcc cgccatgtcc actcatggct caaggccgac agtgtgccat
    51841 tcaaaaggca ggcaatttct tcctgagcga gatggaattt ccaaggcaga gagggaagtc
    51901 gttggtcttg ccccgagcaa aatacatgct gtggtatatc cttcggccca tagtgttgag
    51961 cggtggcgcg cttggagagc cggtactgca attggagtga ttgcatcgcg atgccttcgc
    52021 gcatgcgatg catgatttca ccgggtccca tgacgctgag acgtttggca taccaggcca
    52081 agcctttcgg aagcaccttc gtattgacgg agaaatcgat actaaacata tgcgatatcg
    52141 tgtgcagagc cggattgcag actcctgaca gcaagcaggc aggctcgggt tacggcggcg
    52201 atctctccaa acgacatcac gcaaggaatc ccctgctcca cggtttgaac aaagtgagcg
    52261 atctcagttt tgaacccttt gtctcgtttg gatgttttga agacctcgcg atgagaacct
    52321 gaatagaggt gcgtttcctc aaagtcatcc atggtcaacg atttaccgtc cgcatgtgcc
    52381 tcgaagcgtt ctttggccag gccggaattc ccgcctgcgg tgtagatgat ggatccgatt
    52441 gagccgtctt cgaacgtgag cgtgatgatg cattgatcat cagtgatgcc cgagctctgg
    52501 cggccgatcc gtcgtgcaaa gacggagttg ggacgggcgc cgcataccga ctgcatgtaa
    52561 tcgacaaaat gacaggcctc gccgatgaga cgtcctccgc cgacggacgg gtcttgaatc
    52621 caatgttcgg cgggaatttt cccggcattg atgcggtacc acatgaccag cggattttcg
    52681 cgatgggcaa aaaactcgcg cgccttctct gcgtgagggg aaaaacggcg attgaacccg
    52741 accatcagac gaagtccctt cgcagccttg tcgcaataga cggcatggat ggcgtcaagc
    52801 tcctcctcgg ttaggcacag gggtttttcc acaaacacgt gcttgtcggc ttccagggct
    52861 ttcacaacca gacgaccgtg ggtgtcgtgt cgggtaccaa tgagaacggt attaatggcc
    52921 ggatctcgaa gcacatcctg ggagtcgctg gtgcaatagc ctgcgtgcaa tttttccccg
    52981 agagctttcg cgttgatgcc ggaagccgtg cacacggctc ggatagagac ggccgcctgg
    53041 ctctgcaatt gaggcaataa catgtctttg acgtgatttc cgactccaat caaaccgaga
    53101 gtcaatcgac cggtcggctt gtcgctcacg actgtgatgg aaggttgcag ggcctgttgt
    53161 tgatccagcg ggtacgtaat cagcatgccc atgtagggcg tctgaccttc cgtcatcatg
    53221 cggtaggcat catcggcctt gctgatttca aagcggtgcg taatgagcgg tttgagctgc
    53281 acctttccgt cgccgaccag atcgagaaag gcagccatat tccggttttc tgtccagcga
    53341 acatagctgt aggggtaatc ctgtcccttc tcttcgtatg cgctgtcata gcggcctggt
    53401 ccataggaca tggagagttt gaagtcgagc tcttttttgt aatacggctc tcggggcaga
    53461 ttcatgccga ccgcccctac gaccaccacc cttcccttct tacgggcaat cgctccggca
    53521 atctcgaccg ggctattgtc ctttgtgctg gccgtgatga tcaccgcatc aaccccatgg
    53581 ccttctgaga agccagtcgc ggcatccatc agccctgagg gacgtactgt gaggtcggcg
    53641 cctagttggc gcgcgagatc cagcttggtg ccatcaaggt cagagccgag gacccgacat
    53701 ccggccgctt tcaacatttg tacggtcagt tggcccagga gtccgaggcc gatcacagcg
    53761 atacgatccc ccagacgagg ctctgcctgt cgaacccctt gaagggcgat ggctcccaac
    53821 gtcacgcaag cggcatcttc gaaatccacc gtcgtaggta gtttcacaca gaggttcttg
    53881 ggtacataca ccacctcagc atgggaggca tagttttgac cggcacaggc gacacggtct
    53941 ccgaccgaaa actgagacgc atcagcaccg accgccgcaa cggttccggc gcagctatac
    54001 cccagtgcag ccggggtgtc gaggcgctcg aacacgcgtt gtaaggtatc tttcaggccg
    54061 tctttttgga tggccgtaag gacctttttc accatctccg gacgttccat ggctttgccg
    54121 agaaggcttt tctgtgccac ttggacggtt gatttttccg tgccaggact gatcagtgac
    54181 acgtggttca tcaccaacaa gccaccatcg cgaagcatgg gaggaggaac atcgtcgatc
    54241 ttcagcactc cggagcgaaa attttgaatc acttgtttca tagtgtcgcg ataccaaata
    54301 cgtaaaagtg ttggattgat actgaatcaa aacaaaagaa caggcaggac gagcagccca
    54361 tttcggagac taccttcgtt cgtccggaag gtcaatgctt gaacggaatt tttgcaggat
    54421 tcgcgctgta cgaggtgttt ttgtagagca aagtgctaca gggagccttg ggagaaaagt
    54481 cgggcggcag aatgttctgc gcgccccact tttctcacaa ccggtcttgt gcgaacacaa
    54541 gtcacatgat gcggtggtac gtcagcggca agccgttacc cgcgcacaga ggattggttg
    54601 aaacggccgc gcgcgcccaa cccaaccaga ccgataaggc cggctccgaa caacagcacc
    54661 gtggcaggaa ggggaactgc tttcagcgta tccaatgaac cgaccagggt cttgccgtta
    54721 ctaaacgcca gtgtccaacg attgacattg aaggcgttga ggttcggagc ttgattgccg
    54781 ggcaaggtca cactgctgaa ggccgtgccg gtctcatccg caagattgat ggagaataac
    54841 gacggtgcca gtccttttac gagattgccc gccgttccaa cattcacgga ataaaacgca
    54901 ggattgccgc tgctcacggt cgtcaaattg gttccgccgc cctgaagcac cgccgagtag
    54961 tttccaatcg aaagattcag gctcgaaacg gaattgttat acaactgaat cggcaaactc
    55021 gacggcagca atcccgccgc ggccgtatcg aatgtgtagg tccctgacag cttgaggccc
    55081 gtgttgaacc cgtttgctcc cgttccacct gacgtgaaga gagagccggg aacttcgctg
    55141 atgttcccgc tgaattcgta ggtcacgagt gcagcctcag ccctggtctc ttccccgatc
    55201 ggcagaaccg atcccacggc aagaacgagg agactcagcg agaggttgag tgcacgtttc
    55261 atcatgatga ctccttcggt tgagtaaacg cttcaggatc gtacggcagt gtcgttcccg
    55321 gttggcgagg gggattgagc aagtcctggg ccactcagac cgtggttaag tcgttgaaat
    55381 atggatgatg gattggcggg agccggtgag cgaggtatgg aatcgtacac agggcgttca
    55441 attttgggcg acggaacaaa aacaggagtg ctacggagag acttcgggga gttggcgaag
    55501 gaagaaaaaa aatatggagc ggcgcgccac cggagggtgg cgatcaggct tatcgggtgg
    55561 aagcaaacca acgctcgtac cacaggacga gattcagcag attccagatt ttgaaactgt
    55621 taaatcgctt ctgttggcgg agagctatga aaatgacttc gatggcgttg cgatcgaatc
    55681 gttcgtgcat caacggacta tcgaggatgc gcgaacgagc atagtcggta agccgggtgg
    55741 acagcatatt cgtggccgac ccgcaaaacc cccacttctt tcgatcgatg atgctgtcag
    55801 gaatgattcc acgggccgct tgccgaagga tgtacttcgg ttgattctgt ttatatttca
    55861 gggcagaggg aatggtgagc gcaaacgaaa ccacatcctc gtccaggaat ggcactctgg
    55921 tctcaattga gttggccatg ctcatcttgt cgactcgcat caacaataat tcaggaagtc
    55981 ggttcttgag ttccacgtga atgatcttga ggagcgaatc gtcaatgccc aacgacccac
    56041 ccaggttgcg aatatactcg ctggatgtgt gccgcggaag aaacgcctgg tgaagcaatc
    56101 cggccttttc gttgtcccag aatgcaatgg cattgccgag aaacagcgga tcacccaaca
    56161 tcgctcgtcg cagagcgtcc tgtttctcag aagaacagac gtgggaccca aggctgtaga
    56221 ctgcacgccg cacgaattcc ggcgcctgaa gatacggttc ataataccgg cgattccagt
    56281 catcgaagag atgataggtc tggtagccgg caaaaatttc gtcgctgccc tcccccactt
    56341 gaatcactgg ggtcccggat tctcgcgcca atttggagat gtaataaatg ggcacgcaga
    56401 cagggtctgc gaccggttcg tcttgcaaat aggccatctg cggcagaaaa cgaatgaagt
    56461 cctcgtcgga gatgacggcc tcatggtgat tcgtatggaa atgttccgcg acctgcctcg
    56521 catagtcgaa ttcgttggac ggatcgtctt tgatcccgat ggaaaaggtt tcaaccggcc
    56581 ggtcgaggag ttctgccatg agagcgacgt tcagagagga atccacgcct ccgctgagaa
    56641 agactccgaa cggcacatct gacaccatgc ggcgacgaac cgattgcctg agaaggcggc
    56701 gcagttcgtc cacgtagtcc tgttccgtga gtgacgcaga tcccggctgg aatgtggatg
    56761 gattccagta ccggtgctga cgcattgatc ccttcttgtc acaagtcagg tacgtaccgg
    56821 cttcaagttt taagatccct tcaaagaacg tctgcggcgc gggggcattg gcaaaggtga
    56881 ggtaatgata caacgcctga tcattgatca ccggtttgaa accgggcatg gccgcgagcg
    56941 ctttgatctc cgaagcaaat gtcacacgtc cacggtcgtg tgtgtagtac agcggtttga
    57001 cgcctaacgg gtcgcggacc agggtaagga tctcggatgt actgtcatag actgcgaagg
    57061 catacatgcc gcgcagccgc tgcaaacagc catcaaggcc ccattctcga atggcataga
    57121 gaatcacctc ggtatccgtt tgtgagcgaa actgcgcctg aatgcgtgcc ggcagctcgg
    57181 cccgcagttc acggtagttg aagatctccc cgttgaacac gatccagagc gaaccatcgg
    57241 cggtgctcat cggttgatga ccgagtggcg agaggtcaat gatggacagc cgacgatgtc
    57301 ccagcccgat cgtggaagcg ccttcgcgac gaacgtagac tcctccatcg tcaggtccac
    57361 gatgaatcat ctgatcgcgc atgatggtca gggtgcgctc ggtcagggcc gattcggcat
    57421 cctgtgccat gaatccgaca atgccacaca tgtcgtgaaa tactcctacg gcgagatgcg
    57481 cgcgattagc ccagcgtggc ccacaggtgc cacccgagct tcgacgcaag atatgttcga
    57541 acacgtggcg gcaacagttt caacaccggc agatggcgtt cattgagaaa atgtacacgg
    57601 gtattttcga ggcggaactc ggcgaagtcc gccgcaatgt cctgagcgtc atacactttg
    57661 gaataggggt tgcccggccc atctgtattt cgcatcataa agagtggatt ctggaggtag
    57721 gtccagaggc cgaattcctc ggcgttttgt agatggcctg ccaggagagg atgtgtgatc
    57781 aacggacgtg cgccaatttt cgccagacca aagaggccga tcatcagcaa gcggcgaacg
    57841 atgttgatgc tcaccagata gttcaacgaa tgtttgtgat acatcatgat gactaatttg
    57901 ccaccgggct tcagcacccg gcgaatttcc ggactgactt gacggattgg cgggatgtga
    57961 tgaagcacac catgggagta gacgatgtca aagcttttat cgggataagg gatcgccgtg
    58021 gcactcccct gtttgaccgc ctggtacggg agttggaaga gttcaaagcg cgttttggcg
    58081 cggaacacgg cctctgccgt caggtcaaga ccatgccagc gtccgcctcg ccgaatgatc
    58141 tgtgcactat ctgcagcctg accgatcccg atttcaagca cgtttttccc agcgagctgc
    58201 aggcggtcga gctccccgag aatgtggcct tcagtccgat aacgaaactc gtcatagcga
    58261 ttgaagaacg tcgcccattc ctgatccttg cccactaagg tttcgccgca aggattggca
    58321 tcccaaaact gctcgatgtc gtgaagcgta ttcatcagcg tatgctccag tgtcgcgaat
    58381 ccatcgattt cggattctca tggtagtccg attggctgac ctgtgcaaat agatccgcca
    58441 ttcgtgcggc atagagaggc atcgtatatt cacgttcata tcgcaatcga gcattggcac
    58501 caagcctttg ccggatgtgc ggctcacgga gcagcagaag aattcgctcc gctatcgcgg
    58561 tcggtgagtt cggcggtacc acaaacccgg tttcaccttc catcacggtt tcacggaggc
    58621 atcctctgtc cgtggcaatg actggtagtc ctgcgcacat ggcttccaac accgtcaacg
    58681 gttgcccttc ctgttgaatg ccggggaaga cgaacagatc tccactccgc agaaacgcca
    58741 tcttcttcgc gccggccagc tggccgtgga aaattacctg cgagctcaca ttcccctgct
    58801 ccaattgcgc tctcaccaga cgttcagtat cggcccccca ccaggggccg gcgatatgaa
    58861 attcggctgt gggaaactcc tgcaccacca gcggcacggc gtccagcagg acgaagagac
    58921 ctttgttccg gctgagggtt gagagaaaga cgattcgggg tcctgccgac cggacgcagt
    58981 gtgggccagg gctcccatcg gtcgatagtt ccggcacccc gttcggcacg acggcaatcg
    59041 attcgagaga ggcccacctg tgaaagatcg gtttgagcat gtcgccaagc acgacaaatt
    59101 tggccacgcg tttcagcact tgatcgacgt accatttaaa cgctgttccg ccgccctcat
    59161 agacctgata aaagttcgcc ccatgcagat gtgccacgac ggctgagccc gtaagaaacg
    59221 ctggaaccat aaacaggctg tcacgcaaaa agccaacgcg gctttgggaa agcggaaggt
    59281 aacaaatacg aggccgtttc cggagcagaa tgaagagatg ggcgaaccac tggcgaatga
    59341 agaggaagac gtcccaaaga tccggttgat ccacatgggc gatgccgcgc ctgtccgccg
    59401 tatccagatg gacgacggcc agctgggaat gaggcaacgc gtcgagtaac acctgtgtcg
    59461 ccacactcac accatgataa ggcggcggag tcgggccgat gacttcgatg gtgtcgttgc
    59521 gagtcgtcat gaaatacgct gtgaggggct cggtgtggtt gccatacggg gttcgtgcgg
    59581 cgtcctgaaa ctcctaagaa actccacaat tcttgatgca ctcgttcgac tgtcacaggg
    59641 aagcacccgg cgataggctg cgtcgatcaa actggtacgt tggtctgaag acatgtcgaa
    59701 aagatgccgg accgtctctg ctgaagcctc tggctgcaag ggatcaatac gaaaacccgt
    59761 gaccccgtcc tcgactaaat catgagtggc catggcatga atcgatgaga cgacaggaac
    59821 ttcagccgcc atggcttcac tcagcaccag gccaaaagga tcgtaaagtg tatggaaaat
    59881 gaatgcatcg ctgagggcaa agtagcgtgg gagatcctgc gcctgcacaa accccgcaaa
    59941 gtgtactcgc gtccatccct tttcccgcac cactgtttcg aaatgctgtc ggtccggtcc
    60001 atctccaacg atcagcaggg atgtgtgcgg atgtgtcgtg aggagtctct catagatggc
    60061 gaagagctca tggtagcctt tacgcggaat gagttggccg attgagagca ggactggttt
    60121 tgaaagcgtg ttgagcggcg tagaggtttc cggccattgt ttgcgcgcaa ggacacgatc
    60181 gtgaagaccc gtcacatcca gaggcatggt cgccactaat attcgttctt tcggcgcgcc
    60241 gtagtgaatg aacgcgtctc gagcgtggga ggattcgccg actgcgccag cgctgcgtcc
    60301 gattagccag tgccggattc gacgccgaac aaacgaggcc tgtgctccat cgttgaggga
    60361 cagatgagcc caatggataa atgggatgtg tgcgcgtcgg cagtaccaat acgccgctat
    60421 gttggctacg gcaaacccgg cattcaggac gacatccgga tcaagctgcg tcagccgggc
    60481 ggtgacgccg taattcaagt gcacggccac gggcgcaccc caagggcgca cgtgaaatcc
    60541 cggtaacacg taaaccggaa aaggcacatc ctcaattttc cacagccggt tctcctcctg
    60601 ctgcgccatc aatatgatgg aaaactcgtc cacctgttcg gccatcgcct gaaacaatgg
    60661 tatgcgatag ggtgtgagaa tattcgtcag gacagcgagc ttcataagta gtctgtatca
    60721 gtatcacgca cgcactgcaa cgatcatttt ggctttgctg accaaggcat tcaacgcctg
    60781 gcgatcctga gggtcgagtt tgagggcaat cagaagaaca atatagacca gccccatcat
    60841 caatccgagg cccgggagca acagggccgg cgcatcaggt ttcaacgaca agcccaacac
    60901 tgcgctgcca agacccgcca agagtggttt cacaagacgc tggctgaacg gctgaatgtg
    60961 aaatatccgc cacacctgca ggatgcgaag cccaacgcca aatacctggg tggaagccgc
    61021 tccaatagcc gcgcccaaca ctccccacag gggaatggta caggcgaaca ccccgaaggc
    61081 caggaggccg acgccgatcg tgttccacat gacgagtcgt gagtgtcctc ccatcaggag
    61141 gagattattg ggtgatcctc ctgcgctact gaggagttgt ccggaagcca acacgattaa
    61201 caatgtgccc cccgccctga attccgttcc aaagagagac agcacctcct cgctgaacac
    61261 agccaagagc acaaacaagg ggacagtaaa taagaggacg agttttgagg cagtctgata
    61321 catatggcgt aggcccgcga tgtcgttctg tgcgtgcaat tggccgaaga atggggtgag
    61381 tgaggattcc aatgcgccaa gaattaacgc caaggcggcg gccgtctgga atgcggcctg
    61441 ataaataccg atctcgtgca cattcaccca ggaaccgagc atcagaatat cggcgcgcgg
    61501 ggccacgacg ccgaacacgg tcgccacccc cagcggaagg caatacgtca tcaatcgtgc
    61561 ggcttcctct cggctccaaa gatcgatcat cggtcgacga aatcggacga ccgttcgaag
    61621 gaaaccaagc gtcagagtca ggctgaccag catggcaatg agaagtgcgc cgaacacgcc
    61681 ggccagcccc catccagccg aaataacgag accggcgagg ataaacttgc cgatcggctc
    61741 ccacagatac cttacgacga tgagtggccg aaccgtgtgg tgggattgaa gagacgccaa
    61801 taagatgctt gtcagcgcgt atagaggaat accggccgcc acgtatagca gcaaaatgtt
    61861 cagctccggc ttgtgataga ccgacaggct gatcagtgag gacaatccgg ccagacagat
    61921 ggcggtcaac gcggcggtca aaaaggtgac tgttccggcc atgagcacga tgcgctgcgc
    61981 cccctcagaa tcctgacgtg tccggtattc ggaaataaac ttgatcgcgc cggcatccat
    62041 tcccagcggg accaccaggg tcaaggttgt gaaaaacgcg agggctaatg cgtacagccc
    62101 aaattgatcg gctcccagaa atcgtgccag gaatactccg aacagataat tgagtccgtt
    62161 tccaaatatc gatgaaagaa ggactgcgga gccggcaacc accagttgat cggtctggcc
    62221 ttgatgcgaa tgttcgtcag atttcttcat atcaagtctg gagtcttcac agcatgggcc
    62281 cgtgtcccag agacgttagt ccgacacgct gggtagttcg cgcaatgttt taccattcac
    62341 gcaggctgca tcgttcctgt cggcagagcg cgaaatcatc tgcgcgttgg caaaatcagc
    62401 agaggcccgg agaagtcttg ccctgctgaa cctgaggttc aggccgtgac actatcggat
    62461 attttgtcgt ccgttcacgt acagggagaa cgatgggctc agcaaatgac gctgggggtg
    62521 gttcgaccgt gaagcggagt cccagcgcaa ggactgcgac ataccagtaa aacgcagcgt
    62581 gaaaggttgc cggcgtatac acgagtgtct ctccgatgtt cgcaatggat aggaacacca
    62641 gggagtacaa tgccgcggca tgggccttta cgcggtcgta ccatacgatc ctccataccg
    62701 tgattgcgag gataatggtg tagagcagtg cgcccattcc tcctgaatca agcagcgcct
    62761 ggacatatcc gttgtgcaat gaaaatgttt cattacgaaa cagatcgaca ttgtcaccgg
    62821 ccacgtcagc ccctttcgcc ttccggctgt agagaaacgc ctggtgtcca accgtatacc
    62881 catatccaag gaccgggcga tcccagaagc gatcaagcgc gagggtccag agtgtcgttc
    62941 tgccggagag attctccaac gagtcagatc gcatggatcg tgattggttg agtcccggaa
    63001 tttttgtatc catgatggag accgtcgcca ggataagcag cagccctcca atccccgctc
    63061 caagcaggag gcctttccgt ttggcataca aaaatgccgt gaccagcaac gcgacagacg
    63121 atccgaccca gaagctccgt gaaagtgtca ggtacaggca catgagagag gagagtgcgc
    63181 cgacggcacg gatcagccaa tgaacctttg taaacgcgca caagccaagc agaatgccag
    63241 acgcggctgc gattcccgct ggtttgccga aaagaccttt aaagcggtgc ggattgtccc
    63301 ataccatgcg ttccaccgtc tgatcgaacg ccaaggtcgg tgcgatttta tagagcaaca
    63361 ggcttcccag gcagaccggc agcagggcat acagaacgat acgagcggcc gtgtcatgca
    63421 tggaaggcat ctgttgggct tgttcacaat agctcataaa aaacagggtt actgccacca
    63481 gcgagagaac ctggagcaag actcgtgtcg agtccatgga gacaaacgcc gtgctgcaca
    63541 ggactgcgct gtagagcaga atcagccagt agcgtcgcat ggcaatgatg ttgccctgcg
    63601 taaagagcca ccagaatccc gctgtcagac agagaccctg cgagagggtc cgcaatacgt
    63661 attgatcgcc gatgggtgcg gtatctttga ccagcagcgc aagaatcaaa aagccgaagg
    63721 cataggccat gaaccgcatc ctatctgaaa aggaaactgc gtagctctga acgagctacg
    63781 cattatatac gtcacaatga taggcgatgt aattgaaatt cgaagagcgc gcaatcccga
    63841 tgcgactgga ctattggacg agcaggccgg tcggcgttga gagatccaac ccttttgcgc
    63901 gcgaccattt cggggaggcc ggcgtttgga agggaccgga ccgcaatgca gtgatctgtt
    63961 cgtcgttgag taagctatat agatagacac ctactccatt ccccggtgca acttgacggc
    64021 ttcgaacaat ttgagccgcc acgcgcgctc ccgagctgga cacggagatt tgatgcgctc
    64081 cggccagatc gtagttacca atcagaacgg cgtaggcttc gggccgcttc atggttttct
    64141 gaacggatcg gatctcttcc caatttggtt cggcggggta gcgcatgtcg tagaccacat
    64201 cgatcaagcc ttcatcggcc catttaatgc ttttttggcc ttggatatac aagttcggat
    64261 gcccgggatg tccgcacagg ctgatcagaa cattgggttg gtttttccga agatggctgg
    64321 acacccgccg cacgatatct ccgactgcct gttcgttcca atcagcaatg gcttcccgcg
    64381 catcggcgga ggcgccatag ctcaatcgat ccaacatgag gttgcgattc gtatgatgat
    64441 gatattgccg ggcacactct gggctctggc agatggaaac gctacggatg taatcgagat
    64501 tgatgccgtg aacgggatac cgcgacacac actcaatcat taaatttgag atgaacgtgc
    64561 gaaagtccgg acgatgcacg tcgaatgcgt cggctggcgt gcccggccca tagaagtgcg
    64621 gcaggaattc tcgctgacgg agtgtgacat taaaccaggg gtgaacctca atctgatact
    64681 gcgcggcgat ttccaccagc tttcccaagg gatcaaagct ggaattccac cgggccattt
    64741 cgtccaattt gtaactgtcc cagggggcca ggttggatgg ccaactggtt ccccggccat
    64801 gccagacaca tggcatcacc acgttgaaac cggcttgctt catccgttga cacatactat
    64861 gtgcggaatg ttcggtcacc cagctgaggc tctcatcaaa aatgacccgg ctttcaaagg
    64921 tttcctgggc ctgagcgaat cgcggaagtg aagcgcagag agctgacgca gtgcaagcgg
    64981 ctgagatctg cagaaattga cgtcgtgaca gcatgaacta tctcctcagg gatggcgtag
    65041 cagcggatga tgaaaacgat gttctctgtg atctgcgccg gttgctcgta agcgaacctg
    65101 tcggattgga gaactgggcg acggcttgta cgaatcgact cgaggatgcc gccaatgtga
    65161 gctgctgggc gctctcggca cagtgccatc gcatggcctc gatctcctgc ggcgacgaga
    65221 ggacccggat gatttccgcc gcataggcgt ccgtgtcgtg cctggtcatc ctgccgttca
    65281 gggacgacag atattcgatt tccggactgt gaaacggacg ttcggtcgtc atcagaggaa
    65341 ggttgaacgc aaatccatgg acaatggcca gacccacgag gcccggtatg acaagtagct
    65401 cggccagttt aaaatagata ctcgtttcat gcggatcggt tatttcaccc aaaaagtgca
    65461 cgtcatgcaa gtgcagtgag ctgcacaact gttcgagccg cgcacgctcc tggccttcgc
    65521 caagaatcaa taaagcagtt tctgggcagg cctgttgaat tttggagaat gcttcaagaa
    65581 ggaagtcgac ctgcttttcc gcatacagac gtccggaaaa gagcagcacc tgtttcttgc
    65641 cgagcgcgag acgttctcgt accagcgaca gttggtcatc agtcacctgc cggcgtgctt
    65701 ccctgagccc ctcgacatcg atggtattca gaaatggcgc cactcgttcg ggcggcaggc
    65761 cccggttaca ccagtattga gctcctccat gcgtgtaggt gatgacccca tcgcctcgtg
    65821 tcagtaaaaa gttctttatc gcggaggtga tccattcagc agtggaaccc tgtgtcgacg
    65881 cctgaaaatt gtacccgtgg ccccaccaga tccaggatgt gcagagacgg ttccgctgca
    65941 gccagagaaa aggaatcgtc agacattgca ggccatgagg cgcgatgatg atatccgagc
    66001 cggcgacagc ctcagcaagc ccttccatcc agcagccccc gctcttgtca tgactcaggt
    66061 atcggaggga cagtttccga tgcgaaaagg gcatgggctg ttgttcgcct gaatagactg
    66121 tcagggcata gcctctgcgg gcagcctccg cctgaagcgc ggcgaacagg ggcacacgat
    66181 agtgcggaat atgtagttga atgagtgcaa tagattttac gtgcgacacg catatctccg
    66241 tcggttccta gaccccttgt tcggcgaggg gaaaatgtga catggcctgg tccattgacc
    66301 gtcgtgagga gtatgcaact gacaggcctg cgctacccgc tccgaccgtt cttctaaaac
    66361 catgatgaaa tggggaatta ggacggaacg atacctcctg cgtaccggcc gatgtcgtca
    66421 gtcagcccag tgaattgagc aggattgtac atagcggccg tggcctgaat acgtatgcgg
    66481 ctatgtgttg tagaatgaca agctaggaga attctaggga cgtttgactc tggcctatcg
    66541 tatgtactct gcgagaagtt gacgatttcg gagagaaccc tcgtcaacaa tttggcgagg
    66601 agccaagcac aatgtcagat tgtcgccatt gaatggctac tgactattgg caggtagagc
    66661 gtctgcgggt tggttcggtt ttccgcacca agcaggagac catggtcgtg ttgtcttagc
    66721 gactagggtt ttgcgagtaa ggtcgtcaga tgttctacga tccgcacggc ggtcttccca
    66781 tcccagagcg ggggaattgc gcctttcttc cactgccctg ccatcaatcg ctgcagcgcc
    66841 ggcggcagct tcgctgggtc ggtacctatc agttcattgg taccgatggt caccgtttcc
    66901 ggccgttcgg tgttatcgcg caaggtcagg cagggaacgc ctagcacggt ggtttcctcg
    66961 gtgatgccgc ctgaatcggt aattacgccg cgggcatgct tcaccaaata attgaactcg
    67021 agatacccta acggatcgac atagtgcatc gacggaagtg cttgccctga ttcgcggagg
    67081 tttttggcag ttcgaggatg aaccggaaag accaccggta aaccttgggt accctccgca
    67141 atggcccgta acagtcccag caactgctgc tcgccgtcca cgtttgccgg acgatgcagg
    67201 gtgacaacaa agtagtgatt gggtttgagg gcaagagaac tccagcaggc cggaggccgt
    67261 aaccggtccg catgtttgag cagcgtatcg atcatagtgt tgccgacaaa gaagatacgg
    67321 tcgcttgtga cacctgcccg gcgcaaattc tcattggccg tttcgctcgt ggtgaagaac
    67381 cagttggtaa tggaatccgt gacgacgcga ttgatttcct ccggcattgt ccaatcgttt
    67441 gaacggatac caccctccac atgagccacc ggaatcccca tcttgcgggc gacaatcgaa
    67501 caggccatgg tcgaggtcac gtccccgacg accaagcaga gatggctttt atctttggcc
    67561 agaacttttt cgtagttcac catgatggcc gacgtttgtt cggcttgcgt gccggagccg
    67621 acttccagat tgatgtccgg atccgggata cccagttcct cgaaaaagct gcccgacatg
    67681 gcgcggtcgt agtgctgccc tgtatgaatg agtcgaaaac gaagatggct tccacgcgac
    67741 cgggcggcat tcagcgcatc gatgatcggc gcgattttca tgaaattcgg gcgtgctccg
    67801 gcgatgagat cgatgcgtgt catggcatgg tttcctgtac ggcggcggag gtggatggtc
    67861 gatcagttca ttacataacg aaccttgatc gatccgtcaa caaaaacgac tcgaagacaa
    67921 gtgatgcgaa aaggtgggag gcgtgtcacg gagcgaatgg cgagggctga cacaggcaca
    67981 gaagccggct tgcctgccga tcgccattcg ggagtggcta ctctttttct accagccgcc
    68041 acccctgttt ttgcacacag cgttccgtgg cctggatgat caggagttga atgccctgct
    68101 gcagtttagg gtcgcgcatg gtgtcggcct ggcacttgtt atagtccagg gtaaattggt
    68161 ccttcgggcg attggggtga acccactcgg cagtactgca accagccgaa aaggcacata
    68221 gcatgagaag aaacaccgga cgagtgagag aagtcatgag acgcctcatt tgtgagcggt
    68281 caggagggaa cggaatcagc gagggaagat aaaccgcgaa gcggaggcgc gtcaagccgc
    68341 aggacgcgtc gaaattgtag agcctagggc accggcacgg aaaacgtcac ttccgtcccg
    68401 cgttcgttgt aggtcaaatc ggggaaaaac gccttggcaa gaaaaacccc ccggccgttg
    68461 ggatggcgac tgtcgcaggg ctgttcaggt gtggccacaa aacggctcca ggcaaagccc
    68521 tttccttcgt ccgtgatcgc ataacggagg cgccggcgag ttttgtcatg ggaggcctgc
    68581 accacgacac gccgcctggc aaaccgcggg tggcggcggc gctcctcaat cagccgctca
    68641 aactggtcgc tgctcaatgc cgcgtgtttt tcctggtaca ggatctcgag actgccatgt
    68701 tctacggcgt tgacgatgag ttcgatcaag gtggtgcgaa gatgcaggcg ctgcatctcg
    68761 ggaagcgtca gggcggtctg ctgaatcaac caggtcacac aggcctcgac atgatccgga
    68821 ttggtgccta acaccagacg gtagtccacc tgttcgacgc cagcgatatt ttcgacggtc
    68881 gacggaagct gtcgaagcgc ccgatccagc gccaagccca gttcttccac gagcaggggc
    68941 ttccgtagat agtccccagc gcccgcccgt actacgttca ggatcgtctc agcatctcca
    69001 gactcgccgg tcgcaaggat ggctgttttc ggggaccgca tgcggagttc acggatcagc
    69061 aacacaccgg cctggtcagc cgggaacaga tcagtcatga ggatatcggg ggcagccata
    69121 tcaatcatgg ccaatgccac ttgcggatcc ggcgctgtaa tgacggagat ccctcggagt
    69181 ttcccctcct ccagggccat tgcccaggtc tcgggagagg catcgacgac cagcatcgtg
    69241 ggcgatgcgg cgtgaccaat catgagggaa agcctttttg catgatctca gccagtgcgg
    69301 ccgtcaggcg ttcgacttct gcacgagtct gctcagccag cgccgggatg tcctgcgcgg
    69361 cggcctttcg ggcggcttct tcaagatgtg cagctgcagc gacagcggga cgcgcacaaa
    69421 actccatggc cgaccctttt aatttatgtg cttccttgac cagcaccgga aggtcctggg
    69481 ccgacagagc ggtctgaagt gcggccagcg cctgccccga gcgttccaca aagaggccgg
    69541 caagggtcag aaacaaatcc tgatccccgt cgaagcgatc gagggcggca gccaggtcca
    69601 tgaccggttg cgagtccatt acgccctttc cttttggccc aacagagtat ccagcatctc
    69661 taaccccagc agagcgacgt catcggggaa aatctcccct gccagccact gtcgggcggt
    69721 ggccatggtg tcagcgatgc tttgtccaag actgtggctc cggtgcgctt ccagcgttgc
    69781 ttgcaggcgg tctcgtcccc agagttcccc tgtcggtgaa ggggcctcat agatgccgtc
    69841 actcagcaga tacagacgat ccagcgacag caacggggta tgcatgcttt caaacacact
    69901 gtgcggatcg aatcccaagg gaagactggc catggagagc catcgggatc catcgccggc
    69961 tgcctgcaga aatgctccgc tatggcctgc ggtggcgtag gacagcatac gtgaggagat
    70021 gtccagacgc cccacccata aggtgaaata ttctccgtcc tgcgtcagcg gaaacagacg
    70081 attcgcctcc gtaatgatcg ctcccggatc aaaacttccg accactttcg ccagattgtc
    70141 ttcacggaga aaactcataa gtcccactgc tcgcaaggcg gcagccactc cgtgccccga
    70201 cgcgtcgagg atgtataacc ctagagcatc ggctccccag gagcacactt gaaacaagtc
    70261 gccgcccagg gcaagagatg gctggtaggc ccactgcata ctgactcccg tggccggcat
    70321 gccgggcaga gggagttgcg cgcggacgaa atccgcggct gattgcagct cgctttccaa
    70381 ctccgcttgt ttcgccgaca gcagacggtg agagcgatcg aggtcgtcgc gcgtgtgttc
    70441 gatttcacgt accagggcgc tcgaccgaag gctggcttgc acccgcgcca atacttcctg
    70501 tttgctcgcc gctttgctca ggaagtcatc ggccccgcgg gagagccctt ccgcgatctg
    70561 ttcgggtcgg tcgtgtgccg tcatgagcac gacctggctg gatttcaact cggggtcggc
    70621 gcggatcgct tcgcagacac tcgggccgtc catccccggc atcatccaat ccaagatgac
    70681 cagatccggg cgttgagcac ggatggcggt caagccggcg gttccgtcgc cggcctcaat
    70741 gacccggtac cccaagcgtt tcagtcgtcc ggccataccg gtccgggtga tctcgtcgtc
    70801 gtcgacgaga aggatgaccg gtgccggctt cgcgtcgctg tcagtgccgg attgcggatc
    70861 gatacgtcgt gcgggttcag ccacgtgtcg tgctcctgat gtgtccctta cccggctttg
    70921 ggcaaccggc aggcagccag tgcgtcctgc tccgaatggt agaccggcag cagttgatgc
    70981 aaattcgcca gggtcaggat ttctttgaca taactctggg ggttcaggag accgatcgtg
    71041 ccccgcgtcg cgctgaggct ttgcgtcagt aacgccagtg tcccgagcgc cgaactgtcg
    71101 aggaaccgaa cgccttgcat attcaaaatc agatgacgga cgccgccggc tctgctgcgc
    71161 tccaccgacg ctttgaacgt ggctcgattc gcatacgtca gttcgcccac caagtcgaga
    71221 atgacggact ccccgactcg ccgttcagta atctgcatgc ctgcttcctt tcatcttcag
    71281 aaaagaaggg tcacgcgctt ttcttcgtca cagtggaagc tggcgattcg atcagcggaa
    71341 tggtcttgtg cagattcgcc agctcgatga tctgccgcac cgtcgcctga ggataggcca
    71401 acgacaaggt gcgcttttcg gcctgcaact gccgatgaga aatcatcagg agtcccaacg
    71461 cggcgctgtc gaggaacgcc acctgcgaca gatcgatgac gatgtgttcc atgggatcga
    71521 cgctgacgga cttcaacatt tcctgaaacg gtttccgctg ggtataggta aagttgcctt
    71581 ccagttttaa ggtcacttta tgattgtgga tttcgctggt gattttcatt gctgctcctc
    71641 ttagtgcaaa aggtgaacga tcaggcacgg gtgacttgag tcaaaatcgc tgacgcgatg
    71701 tcgccaagcg gacggacgat gtcggcggca ccaagcttaa tggcttcttt cggcatgccg
    71761 aacaccacgc aggaggcctc gtcctgggcg atggtaaagg cgccggcttc tttcatgcgt
    71821 aacaaccctt tggcaccgtc tccgcccatg ccggtgagga tcacgccgac cgcgttgcct
    71881 cctgcatact gggcgacgga gtcgaacatc acatcgaccg aggggcgatg gcgattgacc
    71941 ggttcatcct ggttgatgcg gaccgaatag cgcgcgccgc tgcgaaccag ggtcatgtgg
    72001 tagttgcccg gcgccacgag cgcatgcccc ggcagcacgc tatccccatc ctcggcttct
    72061 ttgacggaga tgcggcagag ctgattcatg cgatctgccc aggtcttcgt aaaccgttcc
    72121 ggcatgtgct gggtgatgag gatcggcggg gtattgggag ggagcacctg gagcacgtct
    72181 ttgaccgcct ctgtcccacc cgtggaggag ccgatcgcaa taatcatatc cgtggtcttg
    72241 atcatggccg aattgagaga tgtcggacgc gaggtgctcg atgccgccgc cgtggtggga
    72301 cgcacggagg ccgttgcggc agccttgatt ttggcaatga gatcctgcgc cacctggtcc
    72361 atgccttctc gcaaatcgat tttcggtttc gtgatgaaat cgaccgcacc gagttccagc
    72421 gcccggagag tcgtttggca cccagcctca gtgagcgagc tgaccatgat taccggcgtc
    72481 gggcgtccgc gcatcagctt ttcgagaaac gtgagcccgt ccattttggg catttccaca
    72541 tcaagggtca gcacatcggg attcaacgcc ttaatttttt cccgggcgac atagggatcc
    72601 ggtgcgctgc cgatcacttc gatgccagga tcttttgaca acaactcagc caacacctgt
    72661 cgcatcagtg cggaatcatc gatagtcagg actcgaatct tagccattgc cacacatctc
    72721 ctggtcttct ggtgtgcgca tgttctgtgc cgccaccggt ctcctgtgtc aaaacaacgt
    72781 aatattgtct tgttgcaccg tcggttcgac ttcgatccga tgctggtatt ccgtctcccg
    72841 ctcgtagatc gtgcggtttt tcacgcgctc gatcttcttc atcaggacgc ggcccgagtc
    72901 ggtgaagtag tacactttcc tcggatacac atcgcccagg tcgcttttcg cgagggcgta
    72961 gccttccgtc ttcaaatatt ggagcaccca ttccgtgttg cgtgccccga cgtcgatgtt
    73021 accgtcatag atcttccctg ccccgaataa tttcacttcc agacggtgcc ggagtccgcc
    73081 gcgtttcaaa atttcgttga tcagctgttc catcgcgaag gacccatagc gggtcgattc
    73141 tccgccccag gcatcgccgg actgatgctc cttcggagcc ggaagcatga agtgattcat
    73201 gccgccgacc cccacgatgg gatcccggat acaggcggag atgcaggaac caaggaccgt
    73261 atagacgacc atcggttccc ggctcacgaa aaactctccc ggcagaatgc acgccacctc
    73321 gtgggggaat cgtccatcgc gcatgcgccg gatatgcgag aacgcatcgg tgtcgatgat
    73381 ggccatgtct ctcaggattc cttccaatag atcgtcggcg cgatggtttt gaagggatga
    73441 gacacccact gcaaactttc cgagtggccg atgaagagat gcccacccgg tttgagatgg
    73501 tgataaaact tgttgaccag gcgttcctgt gtcgggcgat cgaaataaat catgacattc
    73561 cggcagaaaa tcacatccag cggcgctttg atgggaaaat gatcgtccat caggttcaac
    73621 cgccggaact tgatgatggc ggagaggtgg ggcttcacct tcaccagtcc cgcactatct
    73681 ccccgtccct gaaggaaatg atgtttgacg atttcgggcg gcacctcgcg cacccggtct
    73741 tccgcataca gccccttggc agcatgggcc agaactcgtg tcgaaatgtc cgaagccaga
    73801 atttggaagt tccactgggc cggctgctgg accccttcgt gaagggtcat ggcaatggtg
    73861 tagggttcct cgccggtcga gcaggctgaa gaccagatgc ggatacgctt ctccttctcg
    73921 agagaaggaa gaatgcgctc gcgcagaaaa tcgaaatgct tcggttcgcg aaagaagtcg
    73981 gtcttgttgg tcgagagcag atcgagcatg cgcgtaaatt cttcgccgct gttgtcctcc
    74041 gtcacatact catagtacga ggagaaatcg cccaattgga ggtcgcgcaa ccgctttgtg
    74101 aggcgtgaca ccacgagtga ctgtttgctc tctccgagag agatgccgct ctcgtcatag
    74161 agcagggtcc ggatttgatc gtactctttc ttcgaaatgg gatagtccat cgtctcagct
    74221 ccgataccag acaaacagca tgagatatac gaggtaggcc gtgaccatcg tgccgctaaa
    74281 cgtccagata agcgcgttgc ccattcggcg atgcgtggtc atgccggcca ccatggctcc
    74341 gacgcttccg aaccgtagcc ggtggagccc catatacagg ttgtacgcac ccaggccaat
    74401 agtggtgaca gcgagcagca tgtgcgtgac gaaaattggg acgtacaccg accaataggc
    74461 actttccggc ccctggaagg actctcgtcc aaacagggct tgtttcagga cgtaggcgac
    74521 cagccagata ccgacgatcg tgcaaccaac aatcatgcga tgagaatgat gcgtgacatc
    74581 gtgagacttg gccgctttga cgccggctaa cacgacgaga tacgcgacag tcagactgga
    74641 caggacgagg taccaaagaa gcgttttgac gtccatgatc gtcctcgggc tagaggtgga
    74701 atcgtcggaa ccgtcgaaac gggtccggca tacagacacc cgcaccatca tgtatcggtt
    74761 gtgtcacgct atttcttgag ggggtgggca ctgcacacgt gaggcgaagc tgaggaaagg
    74821 aaacgtcatg cgaggcagcc gcgcgggtgg gcaagatctg cccacccgcg cattcaggag
    74881 gctagaattc ttcgaagtcg tcatccttct tatggcgatc atgtccgtta ccagcagggg
    74941 tccccaccgg ctgcttggca tctgccggcc tggccgtgaa gctcggtttc ttcagggctg
    75001 gctttgtggc aacgatcgcg ctttttgccg gagacttccc gaccgaggaa tgggcgttcg
    75061 actgccgttg ggtctcgcct gcctcgatct tgaagacctc tacctgacgc atcaattcct
    75121 gcgcctggtc tttcatcgac tgactcgccg acgtggtctc ttcgaccaat gctgcgttct
    75181 gctgggtcgt ttcgtccatc tgcatgatgg ctttattgac ctggtcgatg ccctgggcct
    75241 gttcctgaga cgccgccgtg atttcagcga tgatgtcagt gacgcgtttg actgagctga
    75301 cgatttcttc cagcgtcttc ccggattggt tgaccaactc gctgccgtcg ttgacgcgct
    75361 ggatcgactc gttgatcaac cctttgatct ctttcgcggc agttgcggac cgttgcgcca
    75421 ggttgcgcac ttccgcggcg acgacggcga agccgcgacc atgttcccct gccctggccg
    75481 cttccacggc ggcattcaaa gccaggagat ttgtctggaa cgcgatctcg tcgatcaccg
    75541 tgataatatc cgcgatcttc ttgctgctct tgttgatttc gcccatggct tctaccgcgc
    75601 gcaccgtcac cgatccgccc ttgtcggcga tatcgcgtgc agcgatggcc aactgattgg
    75661 cctgtttagc attgtcggcg ttctgcttca cggtcgaagt catttcttcc atggaggccg
    75721 aggtctcctc cagggcgcta gcctgctccg aggtgcgttg ggacaggtct tcgttcccct
    75781 tggtgatctg ctcagcgcct gcggtcacgc tttgagcacc gtcgcgtacc gtcgagatgg
    75841 ctgtgctcag tgtgttcaag gcaccgttga ggctgctttt catctgctcg aactctcctt
    75901 gataatgacc ggtcatcgtc ttggtgagat cgttcgccgc catcgccgta aggaccgtct
    75961 gcgcttcatg caggggcgtt acgactgcgt cgagcatctt attgactccc tccgacagtg
    76021 tcttaaagaa gccgtcgaat tccgcggcat tgatccgttc ggaaagctga cccgatgcgg
    76081 ccgcctcaat gagcttgtcg atttcgacct gcgctttctt ctgtgcgctg atgtcagccc
    76141 actctacgac gttgccgagg tagtctccct tttcgttcat gatggcggca acggcaaggt
    76201 ccagtgtcag tgggccgatc ttgatttccg tcttgtaagg gagatttttg ggattatcca
    76261 gcaacgtgcg ttgttgggcc ggatttttgt gatactggtc tatgttcgag ccgactacct
    76321 tggccactgc aaacgcgggc atgactttct ggatttccgt ttccagtcga cgtaatgtcg
    76381 tcacagactg gttgttggca tagacgatcg tgtagcttcg gtcgcagacc aagacgttcg
    76441 accgcgcgtt atcgagggaa gccttcagac gggacatttc agtctcgagt cggcgtttct
    76501 cggttacatc ggcccactcc aacgcattcc cgagatactc tccgcttggg ctcatgacag
    76561 cggtgaccaa taggctcagc gtcaacgggc cgatttggat gtccgcgcgg tgcggcatgt
    76621 tcgccgggtc ggacaagatt ctgcgctgtt tgctgggatc taaatggaaa tcgtctatac
    76681 aggtgcccac cacagtactt agattgaact ttggcaacac cttcttgatt gccggctcca
    76741 gggtggccag cgtcttctga gccgtcgagt tggcataggt gatgacgagg ttacgatcac
    76801 agaggagaat gttattctgc gactgatcaa gcgctcccag gtaaaattcc gtcatatcgg
    76861 cttgagctgc ggtacctttt ttccccttcg gcttactcat cgtcttttct ccttgtgtgt
    76921 tgtgtacacg ttcggctcca gcgagcatga tggtcttgat ggcgccatag gcctctgtcc
    76981 acgcttgttt gacctgcggc gtccacgctg gtccggcgac ttccccgagc acggccagga
    77041 ggttttctcc aaccgcgtca taatgggccg gcttcgctcc gtatccaacg tgtcgagcgc
    77101 ccatatcttg caggacaggc gtaagcttct ccgggcggcg gagattctgg atgaccagga
    77161 caagagacgc caggagcttc ttcttctgtt ccttaatcgt ggtgtgttta aagagcggct
    77221 tcacggccgg atattttttg aagagccgtt cgtagaaccg ggtgaccaac tcctcgcctt
    77281 tgggcgccac caatttaaaa ctggattcca acaattcgac ctgtaatgcc atgtccttct
    77341 ctccctgggt ttcgagtggt tatgccgcga ctttttccgt ttcctgcaag tcgccgtcag
    77401 tcaggagacg atccatatcc aacagcgcca cgagcttgtc gccggcctta ccgattccat
    77461 tcagaaagct gacatcgacc tgggcgccaa actgcggagc cggttgaata tctttcttgt
    77521 cgatgtcgag cacatcggaa accgcatcca ccacgaggcc catgatcttt tcttttacga
    77581 ccacgaccac gatgaccgta aacatcgtgt attcaatcgt cggcatgccg aacttggtcc
    77641 gcaactcgac gatgggcaca atggtaccgc gcaaattcaa cacgcccttg atatgaggag
    77701 gtgtattggg aatacgcgtg accgccgtat accctttgat ttcctgtacg cggagaatat
    77761 cgaccccgta cagttcctcc cccaattgga acgtcaggaa ttgactgccg tccgttgtga
    77821 tcccgatctg ctgattcgac tctttgcttg ccgattcctg tgatgccatc gtgtcctcct
    77881 cgccctgttc gtacaatctt atgtgccgat gcagttcatg agtgggttgt tatgccgcct
    77941 tcgctttcct ttgccgcgca atattgagta atccacgcac atcgagaata aagccgacgg
    78001 tgccgtcacc gagaatggtc gccccggcca ctccttcaat cttgcggaag ttctgctcca
    78061 tacttttaat gacgacctgc tgttgcccga gaatctcgtc caccatgacg gcgacgcgtt
    78121 cgccttcagt ttcgaggatc aacaaaatgg cttttgtggg gtcggacagc tccggttcca
    78181 accgaaacac gtcatacaag cgcatgagcg ggagataggt cccacgtaca ttgaccaact
    78241 ccccttttcc gacgatggtc ttaatcatct cgcgcttagg ttgaatcgat tccagaatcg
    78301 acaggagagg aacgatatag gtgtccctcc ctacccgaac ggtcatgccc tcgatgatgg
    78361 cgagggtcag cggaagcttg agcgtaaaag tggtgccttt gcctgcgctg gtcttaatgc
    78421 tgacggtgcc gccaagacct tcgatattcc gtttgacgac atccatgccg acgccgcgcc
    78481 cggacacgtc cgtgaccttt tcggccgtgg aaaagcccgg tttgaagatg agcatccaga
    78541 tctgttcatc ggagagtttt tcagtctcag agatgaggcc ctgcttgatg cctttggcca
    78601 gaatcttgtc tcgattcaat ccgcgtccat catcttcaac cgtgatgcag atattgccgc
    78661 cttcgtggaa ggcattgagc cgtatggtgc cctgctctga ttttcccgcg gcgaggcgct
    78721 cgtcaggtgg ttccaatcca tggtcggctg agttgcgcac gaggtgcgtc aacgggtcac
    78781 cgatcgactc gatcacagtc ttgtcgagtt ctgtttcttc tccggaaaga atgaggtgga
    78841 tcttttttcc tgctttgccg gagagatccc gcaccaggcg tgggaatcgg ctgaacgcgt
    78901 tcccgatggg caccatgcga atgcccatga cacgctcttg aatctcccgg gtattgcgct
    78961 ccagttgtgc aacgcgttcc agcaacacgg gcagctggct catgtcaaaa cgggagccga
    79021 gatcacttag catcgactgc gtgatcacga gttcgccgac caggttaatg aggcgatcga
    79081 ttttgaccgt gtccacgcga atggacggcg tctcagcttt cttcgatggt gtgctgcttt
    79141 cggtttgctt tttgagggct tcggaaattt gttcaggcgt cgcgatcttt tgctcgacta
    79201 aaatttcacc gacgcgcttc tgttgcgaca aggcttggtt gagctgcgac tgcgacacga
    79261 cgccggtttc gacaagaatc tcgcccaatg gtttcgtgcc ttccgttgag ccatgggact
    79321 cttcggcagg aggtggcgtg tcaacgatgg tcagggtgct gtcttcgcgg acgaagtcga
    79381 atacggcttc gatgaccttg aggtctttga ccgtgtccat ttcgatggtc cagcccagat
    79441 aacattgctc cgggtccaga tccttcaacg caggtaatcg gctgggatcg agggtgacgc
    79501 tggtgacgga ccccaaatcg cccaattcct tgatgaattg aaccggatcc agtccgcgtt
    79561 ggaacaagta tcgaggggga acccaggtga tcgtgaagtg atgggtcccg gctacctgcg
    79621 attgtcgagg cgaggcagca gcagcactcg gggttgccgc aggtgttccg ccctggcagg
    79681 cttcgagttg ggcacccaat ctggcgatct ggtcttcatc cggagattca ccggtcttcg
    79741 cgcagtcgat caatgtcttc aggcaatcga gcgactggag cagcagatcc gtgatctcta
    79801 ccgtcacgac catctgactg ctgcgcagct ggtccaagac cgattccatt ttatgggtga
    79861 actgcgagac ggcggtgaag ccgaacatgc cgctgtttcc cttgatggaa tgggcgccgc
    79921 gaaaaatacg atttaagaga tcgatatccc ccggccgttg ctcaagctgg agtaagcctt
    79981 cttcaatggt cgtgagatgc tcttgggact cttcgaagaa ggcgtttttg aaatgcgaaa
    80041 ggtctgtgct catggtctct ccgagtcctt cgtcgcacgt cagagggaac gttcgtgtct
    80101 cgctttggat gtgcgagaca taaacgaccc gtaaggatcg agatcggtca gccgggcagt
    80161 accttcttga tcacggccat catctgttcg ggattgaaag gcttgacgat ccatccggtc
    80221 gcgccggccg cctgcccggc ttttttcttg tcgtcggagg cttctgtcgt cagcatgaga
    80281 attggtgtga acttgagcgc cggcattttc cggatttcct tgatcaatgt gatgccgtcc
    80341 atttccggca tattcaggtc ggtgacgacc aggtccggct tggccccgcc attcactttg
    80401 ccgacggcct ctttgccatt gccggcctcg acgacctgat agccggcgtt agtcagggta
    80461 aacgccacca tctgccgcat cgtgggagaa tcgtcgacaa ccaatactgt tttcgccatg
    80521 gcgagctcct taattctttc gacaaccggg tgttacttaa aacaacgtga cattcgcatc
    80581 ttcagacggg gcagaaatct gagcatttcc cgacacctgt ccattcgtcg actgattgaa
    80641 tatggcccgc tcttcttcca tggtgtagct gcggtccagg ttcgccagaa tattcatcct
    80701 ggcggcgatc tggtcgtcag ggtgtctttg gatcaaggcg tccatgatgt cgcgcacctc
    80761 agttaacggt tcgatcacat gttcaagctt ttgtcgtgtg atgtcctgga attggaggga
    80821 cataatgatg tgaccgacgt ctttggaaag ttcatccgag tgcgacttgg aattcatgac
    80881 cgctgaatgc aacgttttgt tgcgatccgc caagttacgg gtcatttggt ccagtcgatg
    80941 cttgatggac aaggtcttgc tcaaatcgac cgatgcgaga ctttccacgg tctgcatggc
    81001 ctgggtcgtg cttctctgca cgtctttgac catcgtgttg atgctgctgg cagcctgtcc
    81061 cgagcgattg gctaatttgg tgacttcatc ggcgactacg gcaaatccgc ggccatgttc
    81121 accagccctc gccgcctcga tggccgcatt gagggcgagc aatcgtgtct ggtccgcaat
    81181 aaactcaatt tcgccgatca tgccggtaat ggctttcgtg ctgcgttcga cctcatccat
    81241 aatggtcgcg atctgaagcg ccatttccga agacttcatg acgtcgctca cgaaaccttc
    81301 gagcatcgtg tccgtggttt tcagaaccgt atcgaggttc atctcgccat caccgaacag
    81361 attcatcgat tcgttggcct ggaatgacgc ccgcgacgca atcgtgctga accgttggcc
    81421 caggtccgtc gcggcctgtt cagtttggtt gatcacactt ttcatttgtg cgttgagcac
    81481 cgccaccagc ggaatgatgg aatgtccgag ttgttcccag atcgcgtcgc gatccatatg
    81541 ttgcttgaga atatgttgtt gtgccgcctc gagcgcctgt tgggcggcag cggcccggcg
    81601 ttggcaccac atccacgaga ggaaggcacc ggcgaggaac gcacacaata ggaataacca
    81661 gtgtaaaatc attggtggat ctattcctta cccgatcgcg cggtaaaaca cgtctatgca
    81721 cccaactcgg tcattcgcgt tcgtatggga tcagtcattc ctgtcaggac acaatgctcc
    81781 gaccggcgaa cggcgatgag cagttgaagg gcggcggcat ccagcttgtc gatctcagag
    81841 agatcgattt cgacctgcgg atgggtcgct gccgcttgtt tgacttcctc gcacaaggca
    81901 cccacctcaa aaatcgtcag atcaccaacc ggcttgagcg tcatacactc gttcctttcg
    81961 agaggcggtc gctacctcac gtgactctgt atcggtgtgt ctcccaaaaa cctttacacg
    82021 taaggggttg tatttagcac tggagtcgac tgaggccttt ggaccatggt catagagccg
    82081 gaggacccgg attcggcagg accgaatcga gggactcctc cgtcaggttt ttctcgagca
    82141 caatgatttc tacccgtcta ttcttcgtcc ggccttcagg ggtgtcgttg gtggcgatgg
    82201 gtttagagtc ggcaaagccc gtggctgaga gatgcgagat ggggacttca ttcagttcgg
    82261 agaagatccg gaccaccatg accgcccgca cggccgagag ttcccaattg gaaggaaact
    82321 gagcggtccg gatcggcaca ttgtccgtat ggccgagtac ccggatgtgc cgatccattt
    82381 caatgaggat ctgggccagg gacttcagga acggaagcgc ttcggggcgg acccgcgctt
    82441 ccccgctgcc gaagagaatg gattccggca gggaaatcat gatggtcccg tttccggtct
    82501 cgatgatttt gatgtccggc atttccagcg caagcgacgg atgaatcttt ttgatgacct
    82561 ccttcatccg ccgaataacc ggatcgttcg ggctcgacat gtcggtattg atcatcttgg
    82621 gcttggagtc gccgacggcg aagggcagcc ggctggaggg cgtgctattc accggattca
    82681 acgccgcctt gatcgaatca ctgaccgttc gatatttgcc ttcgttcaca gacgacaccg
    82741 aatacatgac cacgaagaag gcgaacagca gcgtgatgaa gtccgcgtag gacaccagcc
    82801 agcgttcgtg attttcatgt tcttcgtgtt ttttcttcgc catggcttca acccgtgcgg
    82861 gctatgcggc actcatgcag acgctcggtg tacatctgtc ccggcggcaa ctggcggggt
    82921 gacgcatcac ttcttgtctt ccttggtgcg ctcgtgcgga gggaggaagc tttcgagttt
    82981 ctcttgtaga aggcgggggt tttcgccctg agccagaccg accagcccca tgatcaccat
    83041 cgtgcggagg ccggcttcct ctttgagttt gaacttcatc ttgttggcga tggggagaaa
    83101 aaacaggttg gcgagtccga cgccatatac cgtggccacg aatgccaccg cgataccacc
    83161 gccgagtttg gatggatcgg cgaggttctc catgacgtga atcaaaccga gcacggcgcc
    83221 caaaataccg acggtcggcg cgtatccacc cgcggcttcc cagaccttcg ccgcgtggac
    83281 gccttcttct tcatgatgct cgacttcgat ttccaggatt tcctgcagca acttgggatc
    83341 tgtgccgtcg acgatcagct ggatcccttt cttgaaaaac gggtcgtgaa gatctttgag
    83401 tttgccttcc agtgcgagca agccttgttt gcgcgcgacg ttggcaagat cgagaatttg
    83461 cgtgatcgtg cccttcacat cgtgcggtgg gttggtaatg acgagggtgg ccccggtcgc
    83521 cgccttgatc acaacagaca gcgggttctg cacgcaacag gcgccgaagg tccctccggc
    83581 gacgatgata aacgccgtca attggaggat ggatccgaga tggccccctt cgagtgcttg
    83641 tccaccgatg atcgagccga gggctacgac aatacctatg attgtggcga tatccacagt
    83701 tcagttacct caccgtccca gcgcactgtg gccttcgcca tctacctaga atggtgggct
    83761 tgcgcccccg ggaaccgctt tgatagcgtg caaccgaatc acacacgttt tccatggagg
    83821 tgttcttgtg ggccctgccg atagcttgat cctcgatgcc aaacaggcca tcctcgatga
    83881 acaacaccgc aagtttcagg tcttgcagaa ggaaggccgt tggacggaag ccatgcaaca
    83941 gtttcatgtc accctaaact gcgcgtcgga cgttctggcg gagtcgattc agttgctgga
    84001 acgggtcctc gacgcacgga atcgccgagg accctcccta cccgattcgc ccgatgttcc
    84061 ccagtcctga ttcgtgctca ctccccatgc agaaggcagg ccttcactgc ccatccttcc
    84121 ggcttaggct gcttcccggg ccaagagaag ccggctcaga tccacgagga tcagcagccg
    84181 atcatcaatc cggccgactc cctgcgtaaa ctccgccccg gccatggtac cgaccgaggg
    84241 cggtggttca atcgcacttt tcggcacacg caggacctct tccactgaat cgacgatcag
    84301 cccgaccaat cgcgcctgta ccgatacgac cacgatgcgg gtctgagtgg tctgctgtgc
    84361 cccggtgagg ccgaagagtt tacgaagatc cagaacggga atgatgcggc cccgcagatt
    84421 gatcacccct tccacatagg gaggggtttt gggcactcgc gttacttcca cgatccggtt
    84481 gatctcctgc acgctcaaga catccaccgc gaattcttca ctgccgatca ggcagatcac
    84541 gaactgcagc agatcgtcgg cggacttctc gaccagacgg tccgcagaat tttctgcggc
    84601 cgcctggatg tgagattgca cttgttgttc agtcgcactc atgctgggct ccttctcgtg
    84661 gttggctgct tacagcttga atccacccac gatcccctgc aattcgaccg ccaactggct
    84721 gaggtcctga ctggcctttg ccgactcatg tgcgccggac gaagactctt tcgtgacctt
    84781 cgccacgttt tcgatatcgc tggcaatctg ttgcgtcgca accgattgct cttcggacgc
    84841 cacggcaatc tgacggatca tatcggcgct ttccgacacc atccgcacga tctgggagag
    84901 ggcttcgccg gtcttgttga ccaggtccac acccgccgtg actttctgcg tgccctgctg
    84961 catcgaatcg acggctccgc gcgtatcctg ttggatctgg cggatcatat cgccgatttc
    85021 cttcgtggct ttggtcgttc gctctgcgag cttccggact tcatcggcca cgacggcgaa
    85081 tccacgaccc tgttcgccgg ctcgagccgc ttcgattgcg gcgttcaagg ccagcaagtt
    85141 ggtttggtcg gcgatgtctt cgatcgtgcg gacaatttcg ccgatttgat cggatgattt
    85201 gccgagatca gagatgatgg tcgccgagtt cgacaccgcc tcggacaact gctgcattcc
    85261 gctgatggtg ctcgacacga ccgttccacc ctcctgggcg gtcttgaccg tatcctgcgc
    85321 caggctcgcg gctttgccgg agttctgcgc aacctgtccg accgtggcat tcatttcttc
    85381 caccgcggcg gctgtctgcg acgcacggga cgtcaaggta tcggtgccct tcgagatctc
    85441 ctcggcggtg gccgacagct cgactgaggc ggacgcgacc ttatccgtca cgtgagccac
    85501 cttcttgatc atgtgctgca acttctcgat gaattcgttg aagtactggc ccatctgcgc
    85561 gatttcgtca tggccttcgg ccggcacccg cttcgtgaga tcgccttcgc ccttggcaat
    85621 gtcgcgggag atctcgctca tcttggccat cggctgcaag acgatgttgc gcagcaacag
    85681 atacatgacg acgagaatga tggcgacgat ggcgcccatc aggccgcccg tctgccacat
    85741 ggagcggttc gacaatgcga tcgcttcggt catcggcacc gacatgctca gcatgcctaa
    85801 cacgtcacca acctggttgt tggtatggca gctcaggcag gccgtcgaag tggctttgtc
    85861 cacggtggca cgacggaacg tcggcacgcc gttgacttcg tcccggcgcg cataggattc
    85921 ggcgccgctc atgatggccc gaatcgcctc gttctcaaaa ttgtctttcg gcgtattgga
    85981 cggattcatg gggttctgac tgatgagccg tacgttgtat aaccccgtgc gattagcctc
    86041 ttcacccatt tcacgaacgg ccgttgcggg gaacggaatg gcatcggcca cgcctgtatg
    86101 gtctttcagc acctggattt cattgccggc cttggatttc ttaatttttg ccacataatt
    86161 ctgggtaata taggcgcggc taatcatgat ctgcgtgctg accacattca ttcgaccagt
    86221 caatagggtg tcgatcttcg tttcttcctg ctgatacagg accacaagcc caagtgtgat
    86281 caccactagg gctactgcgg aaatcgatat aataaacttc ggcccaatcg acatgtgctt
    86341 catcatgctc cccataactc ctcctagctg tccatgcgtg aacggttgaa tgaacgatcc
    86401 ctgtcacacc atgttcatga tctcgccgat gacttttgaa agtgacacca ccttctccgc
    86461 acatcctgct tcgaccacgg ctttcggcat gccgtatacg acacttgacg cttcgtcctg
    86521 cgccacggtt cgacctcctg ctgctttgat ggccttcatc ccctccagtc cgtcatgccc
    86581 cattccggtc aaaatcactc cgatgctgcg ctctccgaac aatgcggcga ccgactggag
    86641 catgatgtcg acggatggcg aatgggcatg cctttcataa ttcggcgaca atttgacgac
    86701 tgacgtcgtg atggacttct tcacgacccg gaattgcatc ccgcccggag ccaccaacac
    86761 ccgccccgct ttcacctcat cgccgtcaac cgcttcccgt acttccaatg cgcacaaatt
    86821 gttcaagcgt tcagcgaacg gtttggtaaa cgaactcggc atgtgctgca cgatgacgat
    86881 gccggccgga caatcggcgg ggatcgtcgg gacgatttca aacaaggctt gtggcccacc
    86941 cgtggaacat ccgatcgcaa tgagtttggt gccgcgtgtt acggagacgg agcgactgct
    87001 caacgctttg gcggctggca cagcgagctt cggtgcgcct gtaacgttca gtcgtttcag
    87061 tttgctgccc gcatatctgg ctgcgagcac cttggggacg aggatttttt gaatctcggc
    87121 gattttcgat gccacgccat cgagttgttt ggggataaaa tcaaccgccc cccactccaa
    87181 cgcctgcaat gtctcttgcg cgccttcgac cgtcaccgaa ctcaccatga tgaccgggac
    87241 tggattcttg gtcatgatct gctgaagtgc ctgaagcccg gtcatccccg gcatttcgac
    87301 atccatcgtg acgacgtcgg gcttgagctg ttgtacctgc tgaaccgctt cttcaccgtt
    87361 gcgtgcgact cccaccacct ggatctgttt gccttcttcg agcatcgtgg tcagactttt
    87421 ccgcatgaat gcggaatcat cgacgactaa gacgcgaacc ggcttcgcgg cgctctgcgg
    87481 ctgtgtgagt ggaagtgcca taggatcttt agcgatacat cggccgtctc tgacaaaagc
    87541 ttgaatcagc cgtcaccctg acgccagggt ctgcggcgat atcaggccgc ttttttcaca
    87601 ttggcgttcg ggttttgaat gtagagcgcc agtttctcgc ccagcatttt tgcgtcaaac
    87661 ttcgtgatgt aatccgtcgc gccgaccgtc cgtcccttct ccatgttgca ggcaccggtc
    87721 agagaggagt gcagcatgac cggcagatgc gccagtctcg gatcagcccg gatgtgtttg
    87781 gtcaaggtaa agccgtccat ctcgggcatt tcgatgtcac tgagaatgca ctggatctga
    87841 tccacttgct ctttaccttc tgcggtggct tgatccgcca acgcttgcag cttttgccag
    87901 gcttcgccgc cggtcgtcgc aatcacatac gacatggaga ggcgatccag tgctttgcga
    87961 atctgcatgc gggccactga agaatcgtcg gcaaacaaga cgcactttga tcggagttcg
    88021 ggggcgatcg tcatcccggc gaagacatcg tcgtccgtgc gcgggcaaat gtcgttcaag
    88081 actttttcca cgtcgaggat caagaccatc cgcccgtctt ccagcatcgt gacggcagtg
    88141 acggctccct tgttgttctc ccggacgatg gccggcggcg tcttgatggc cgaccaggaa
    88201 aagcgaatga tgcgatccac gccggcgacg agaaagccct gcaagctgcc gttatattca
    88261 gagacgatca ggtagggatt cccgccggga gccccgttgc cctgtccctc ggtttccatt
    88321 cccaggccca agcttcgctt cagtccgacg acggggacca tgatgccccg gatattcgcc
    88381 atgccgacga tgcggttgtc cgcttccgga atctgggtca gctccggcag cttcatcacc
    88441 tcacgcacct tgaagacatt gatgccgaaa atctcgtttg tcccgagctt gaacagcagc
    88501 aattccatct ggtttgcgcc ggctagcctg gtcctggcat cgatttcatt gatcagtgtg
    88561 gacatacttc ctccgatctc gcgcgtctca gttcatcgac tattcttgaa cccgtctccc
    88621 cgcccacagc tcagggcata cacccttgtg tcaggcggcg atgcccgggt tatgccacgc
    88681 ttgtgcattt tgaaccagct cggacgtatc cagaatgagc accaccttgc cttcgccggt
    88741 gatcgtggcg cccgatacgc ccttgacggt ttcgagataa tcccaaatcg acttgatcac
    88801 cacttcttcc tgggatcgca actcatcaac caccactccc actcgacggt ctcccaatgc
    88861 ggcaacgacc acgtagaagc gctcacgatt ggcgtccgtc ggaatgtcaa actcctgagc
    88921 caggcgaatg agcggcagca cccggtcacg caggtgcagg acttcacgcc cgttgatggt
    88981 cttgatctca gagcgagaaa ttcgcacggc ttcaatgacc gtgctcagcg gaatggcgaa
    89041 aatcgaacgc tcgacttcca ccatcaaggc ctgaataatc gcgatcgtca gtggcagctt
    89101 gataatgatc tggctgccct tccccggctc ggattccaga tccacgctgc cgttgatttt
    89161 gcggatattc gtgcgaacca cgtccatgcc gacgccgcgt ccggagacat ccgtcacttt
    89221 ttcggcagtg ctgaatcccg gcaggaaaat cagattgaga atttcacggt gctccatcgt
    89281 cgcgagttcg gcttcgctga tcagcccttt ggccaaggcc ttctccttga ccttctcgac
    89341 ctgaataccg cgcccgtcgt cgttgatccg aatgacgatg ctgttgcctt cctggctcgc
    89401 cgcaatggtc agttgtcctt cccctgcttt gcctttcgcc tggcgctcgg ccggggtttc
    89461 gattccgtga tcgatggcat tgcgcaccag gtgtacgagc ggatcgccga tctcatcggc
    89521 gacggactta tcaagctccg tttcctctcc gcgcatttcc aaatgaacct gcttgttcag
    89581 tttttgcgaa aggtcgcgca ccatgcgagg cagtttggcg aacacttttt tgatcgggag
    89641 catgcgggtc ttcatgacgg ctaactgcag gtcggtcgtc accaggttga gttgcgcgag
    89701 tgtttcgctc agcacacgaa cctgcggatc agattcgtgc tgctgctcca attgggtgcc
    89761 gatcttgatc aaccggttgc gcccaaggac cagctcgccg accagattca tcacactgtc
    89821 gaggcgtttc gtttccacgc gaatggtggc atcttcttcc accggcttcg gctgtttatc
    89881 ttgtttgtgc agggcttgat cgagggcgcg ttcggtaatg gcttttgcct gcaagagaat
    89941 ttcgcccagc ggagtcttcg gttccggttg atgctgttgc gccgtaaggg catcaaggac
    90001 ctgctctttg gaggccaggc cgtcgttcac cagaatttca cccagcgtct ggggagcagc
    90061 gaccggagcg gccgcggcag gtgccgacga ggcggcttcg actttcgggg gcgcaacggc
    90121 ttccgtctgt accggcgcag cagccggggc tgtgttgccg ttcagaatgt cgtcaagctt
    90181 tgcggcaatc gatgccgtgg cgacgtggtt gtcagtgcct gattcccgaa tgtcggccat
    90241 gatcgccttg atgacgtcga tggtttcgag aatgatactg atgatggccg ggttcacggc
    90301 catttcgccc tggcgcagct tgttgagaat gttctcgccg cgatgggcca catccaccag
    90361 atggttgaag ccgaggaagc cggcggaccc cttcatgcta tgcatcgcgc ggaagatctc
    90421 gttcaggaga tcggtgttgt tgggatcgga ttccaacgtc acgaagcgct ggtccaacac
    90481 ttccagcatc tcgttggact cagtcagaaa gtcattcagg atttcctgca tttcatcgct
    90541 cataacccac ctcagttaaa accgaattgc ttcaggattt cgtcagccaa atcctgattc
    90601 atcgatgtat tcttggtcgc ttccaattgc ttcagcattt cgctggcctt gtcctgctct
    90661 ttttttgccg cctgcttttg ataggggccg aagaccacca cgagttggag cagtttgtgt
    90721 tcgacttctt gcaggatggt gacgagcttg ttgacgcttt gtgccaccag atcctggaat
    90781 gacaaggccg tcatgatatc gagcagccgc ttgtcgtcca cgttgatggc attgccgacg
    90841 gcttgcatct gctggaggag tgcgggagcc gcctgcgcct tctgcatggc gagcgtcagg
    90901 tccttgatca tgccgctgat tttcatgtga ttgtcttgaa tggcctcaac ctcgagcatg
    90961 acccgatgag ttccctgctc ggtcatggtc ttgagattgg tgaggtggct gagcgcttgc
    91021 ggcagctgct cggtcgaggt gctgaccggc gtgctgaatt cggacaaggt cttcatcgtg
    91081 gtgtcgatga agcgggccaa ttctccgagt tcctcataga gcttggtatc aggtgctttt
    91141 tcttcctgct ctgattcatg cgtcgctggt tgcgactggg ccgccgcgcg tggttgtgcc
    91201 atcgtccccc ccaccggtta agagccgatt acttgaaaat cttattgatt ttgtcctgca
    91261 tcgtctctgc ggtgaacggc ttgacgacgt agttactcac gccggcctgc acggcctcca
    91321 tgagattttc cttctgggct tccgccgtga ccatcaggac cggaattttc ttgagcgatt
    91381 catccgcgcg aatggcgcgc agcatgtcga tgcccatcat gacgggcatg ttccagtcag
    91441 acaccacgaa gccgtacgtg tcggctttga gtttggtcaa cgcttcttga ccgttttccg
    91501 cctcttccag gttgttgaaa ccaagttgtt tcaggatgtt cttgacgatc cgccgcatgg
    91561 tggacatgtc atcgacaacg agaatcttca tattcggatc agccggcatg ggtcctcctt
    91621 actgtttctc atgaatgact gaacggcccg catgaatggt tttgaagtgg cctgccgcgt
    91681 cgtgcagggt ctcggaaaat ccgatcatca agtatccctt gggacgaagg gcgtcgcgca
    91741 gatccgagac aatctgcgcc ttggcttttt cgtcgaaata gatgaggcag ttgcggcaaa
    91801 aaatgatatc gatgccgcgg atcagcttca gtctgggtcg gtcgtacaaa ttgacgttca
    91861 tgaaccgcac catgtctttc accggttgca ccagcgtctg ttcttctttc ttcccggtga
    91921 agtagcgcgc aagcatcgcc ggcggcacct tgcgcagcga atgggaggaa taggtggcgg
    91981 ttcgtgcgat gttcagaaca ttttcactga tgtcggttgc gaggatatcg atggtccagc
    92041 cgttcagcgg aggatagtca cgcagcagca gcgccaaggt atacggttcg tccccggtcg
    92101 aacaggcggc gctccagatg cgcaattgtt tcgtctgggc gttcgttttc atgacttccg
    92161 gaatcatcac cttcatgaaa ctatcgagct gggcttcatc gcggaaaaag tatgtttcat
    92221 tcgtggtgat gaccgtatag agctcggtga tttcacggtc ccggtaggca tcgaagcgca
    92281 aaaagttgag atagctttca aaggtctgac agcggcaggc cttcagccga ggaagcaagc
    92341 gactttcaag cagatacgtc ttgttgtctt gaaagtgaat gccggtcatc tcatagatga
    92401 gatcccggag ctgcttgaat gtgtccgggc ttagcttcgg ggcgggcatt tccgttttgc
    92461 gcaccgcgtt tgactcggcc atcccttacc tcgtgtgatc cgctaaaggt gagctcaatc
    92521 aacggacatc ccgggagtcc gcgctgctca cgtgttgtcg tctctgcagc tgctctccaa
    92581 cgagagttca gtgctgctgg gtccggctgt gcatccactc gtgaatgtcg cgtcggagga
    92641 accgccagtg ctttccgatt ttggaagccg gcaattctcc gagacgggcg agtttataca
    92701 ccgtggattt gggtacacgc agaaaccgcg cgacgtccga cacggtgaga atctcgcctt
    92761 ccgaaggcga tacactgtcg aagttgacgt tggttgtggg cgcaatagcg ttgttcataa
    92821 cggatatggt atcggtgggc gccatctcaa actttagttg ccggttcttg gacgatgggg
    92881 tttaataagg cacaggctgg agtcgcaggg agatattctc cctatgggct tattccgctc
    92941 aggttcctag gccgaaggac cgacaacaga catcggcgaa cacacacagc tgagagagag
    93001 ttgcggatgg ccaccatcgt atcgatagga tcagggaagg gcggtgtagg aaagagcgtc
    93061 attgccgcca atttggccat gctattggct aaacggggca agcgcgttgt gctggcggat
    93121 ctcgatgtcg gcggtgccga cgcgcacatt ctgttcgggt tgctgaaccc tccccgcacc
    93181 ctgaccgatt ttgttgaacg gcgggtggag cgtttggagg aggtgcttca gcctatttcg
    93241 gcccatcctt tcctgcaact cctgcccggt accggggata cgttagccac cgccaacctc
    93301 ccctatgcca agaaaaaacg cctgattcgc cacttttccc agttgcaggc tgatgtcatc
    93361 atcgtcgata tcggcgccgg caccagttat catgcgctcg atttttttct catggccgac
    93421 tgctatctca cggtggcgac accagatccg acctcggtcc ttgatctcta ccggttcatt
    93481 aagctggccg ccattcgacg tgtattatcg gcattcttgt cccgtgacgc ggtgagcgaa
    93541 gcgctgtcgg atcgcgattt cgccagtatc gacgaggtga ttcaggcggt gggcgagaca
    93601 gatccgaatg caaaagagac ggcgagtaac accttgcaag ggtttcaacc ctacctcatc
    93661 gtcaatcgcg tatcaggcaa atcacgggtc aacgtgctgc aattgaaaaa gctgctgaag
    93721 gagtatgtcg ggggagacct gacgatgctg ggcgagattc cggacgatcc ggcgatggtc
    93781 cgggcggttc gcagctattt gccggtggtg gagttcgaac cgaccgcgcc ggcttccgtc
    93841 gccctcaacg gagcggctga tgcgctcttg gctcagctca ccaaaccagc gacgatgccg
    93901 cagccatccg ctccctctcc ggaacgggcg gcctagacgg ttagcgcctc aaatcctgct
    93961 caccattcag agatgattat gcgcggcctt cctcgttcgt agccgctcgg cttgaatctg
    94021 gaggatatgc cggataatca gttcctgctc gtccccgccc agatcgacaa actgggtggc
    94081 gagatgaaat cctgccttcc cctcatcgag cggcgtcacc cggatgatct tggccatggt
    94141 ttcaatcatg ctgaacggcg gcaggatcac tttcaacatc agcaggtcat cggcctgaaa
    94201 ttcgcgaggt gtgttgaatc ccaacccgcc cgcactaata tccacatcgg tcagtcgcgc
    94261 gatgctcaca ctgcccgggt gactcttgac catcgacttg aggatcgtct ccagcatcca
    94321 gtcgattttt gatacccacg gcaggagcgg agaacccgca aacgtctccc ctgcccgtac
    94381 cagcaaatca acggttggct tcgatacggc cgtggcaatg gtgtcttccg ttgccggcgg
    94441 caaatattgg ttcatcgcct ccagcggctc gtcggctcgt cgatattcta gcagaaggcg
    94501 atcgtcgatg cggagccact cgcgccgctc ttcgttcttg atgtcgtgat gcgggcgctg
    94561 cagcggccgc tcaggtgaag gcctcatacc aaacctctct agtggaaggt cacggggaag
    94621 ccagggtatc tggctgcaag aacgctaggc ttctcgatgt atcgttacac tgtctgaggc
    94681 cagttgtccg ctactttcgc gtaattggcg caggtggcgg gtcacgtgag aggcctcagc
    94741 caagagagcg gagattccag cttgcgcgag caggatggcc tggcgaattt cttcatccat
    94801 gatgagaagc tgttgtgcaa cggtgtgatc aggtttgcat gcggcaagac tgagtccgcg
    94861 ctcgctataa caggcgtcga cttgatccca gtcccctgct cgggcggcgt tcagtgcttg
    94921 gatggtgagt tgttcgatgg agcgacggtc gtgaggggaa ccgggatggg aggaactagg
    94981 cgacatgcgc caccgcttct tgtcgtgcga cgacttgcca tccttcccgg agggtcgtca
    95041 ggcagcgaat cggtccatcc aagtgtttgc cgttatgccg aagattcgct tgtatgcatt
    95101 gctggaccat atagtcatac agccggtgca gggacacggc gatctccccg cctcgctcga
    95161 aatccaggac gctggacaat tctccgacga tggccatgct gcgatcgagg aatcgggcct
    95221 tatccttgta gttgttcgtg agaatggctt cccgggcgag ctccatcgat tgaatcgcag
    95281 aatcgtagag caacacgatg agttgtaccc gactggctgt catgacttga gtctgttggt
    95341 aggcgttagc tgccgtagca atcatggtga ccttatctgg ttattgtaac gcctggagag
    95401 cgctggtttg gcctttgagt ttttgaagta atgcatcgag ggaggcgaat tgcagtcgca
    95461 accgctcctc atattgcgag gcgatgtctt ccttgcgacc gatttcatcg gtgagtttgc
    95521 tgatctgact ggtgatagct gtctttctca ccgtaaaggc gccggtatcg atggcatcga
    95581 ggaaatcgac ggccttgacc acccggtccg caatgccgct ggatgttgtt tgtgtgacaa
    95641 acagggcttt cgtggcgctg tagttgctcg ccaatgcggc atctaatttg gcgtcgtcta
    95701 ccgtgacggt tccatcgcgt tccgttttaa acccgacggt tcccacgctt ttgtacgtgg
    95761 acagtccgct gacctctccg gaaagcgcag ttcgcagctg gctcaggacg cttttcgccg
    95821 tactctcgtt gaagaaaatg ccgccggtct tcgtcgagat atcataggtt gtgcgctcat
    95881 tgacgaattt cacaatatcg ttgtaggcgg tcgccagagc tttgatattg gttttgacac
    95941 tgtccggatc ggtcgtgata ttaacggtga ccggttccgg cgtgggagtg gtgacggtct
    96001 tggatttcaa cgtgagcgtg acatcgggaa tggcgtcgct gatcacatta ctttcacgct
    96061 cgatggaaat cgtcgtctga cccggttcac cgatcaccac aatggcgttc tgtcctgctt
    96121 gcagcgtact ggtgccgccg gttccgctcg tgttggtgaa gtctaagctg gtggtgtctg
    96181 tgacaaccgt cacggcattg gcagcgcccg tagcagtggc cgtgagcgtc agtcgatagg
    96241 ccggtgtgga tacagttccg gtgttgatca cggaggcggt gacaccggct cccagatcgt
    96301 tgatggcgga acgaagatcg tcgagcgtag cgccatcgtt gagcgtcacc gtttgattgg
    96361 cgccggttcc gaccttgaag gtaaaggtcc ctgagccgcc tgagacgatt ggagtggtcg
    96421 tcgcggcgac cgccttggca gtgctgttgg taatctggtg cgctttggct aactgagtga
    96481 cctggaccgt atagctgccg gtcgccgcgc ccacgccggc ttgagcggtt aatttggtct
    96541 cgttgctgac ggtggtggtc gtgcggtcaa aactgtttgg gaggcgaagc gcattggctg
    96601 cgctttggag tgcgagcagt ttgttgccca gggtcccgta gtcggtcagt ttagtctgga
    96661 ggtctttctt cttcgcgttt aacgcgtcga taggcacacg ttggacttta gccagctcag
    96721 tgacgacctg gccaaagtcc acgccattgc ctaacccgcc aaaactgatc gccatgacat
    96781 ccctttcatg ccgtgatgca gcttacacct tgtggtgcag gagcagcccc gtgggggtct
    96841 ccagcctctt cgcaaggtcg atgacttcct gctgcggtat ctggcggatt acggtaccag
    96901 aatccccatc catcaccttg accactaccc gatcgagatc cggatcgacg gtaaactcca
    96961 gcctggagtc tgccttcttg aagacctcac gcacgcgcgt gagcgcctgt tccagatctt
    97021 ttcccttcgt ctcaggggtt gacgactcag gttcgggagc cttcgcctcg accttctttt
    97081 cagtcgtatg ctgaggcccg ctttgcgtcg cttgaatagc ggctgcggga aggtctttat
    97141 aattggaaac atcgtggacc atgttaccct cctcggatca gtcctggggt agccctccct
    97201 atggagagct acccgccggc tgaagcctta ccctcgcagc agcgctaacg cttgctgtgg
    97261 cagcgaattg gcttgcgcca aaatcgcgat accggattga gtgaggatct ggttcttcgt
    97321 gaacacagat gtttcctgag caatgtccgc atcgcgaatc cgcgattcgg ccgcggtgaa
    97381 gttctcggcc gtgaccgtca gattctggat cgcgacttca aaacggctct ggatagaacc
    97441 gtaattggcg cgggcggtag cgaccgcgct gatcgcgctg tcgatcttcg ccagcatcga
    97501 ctgtgcggcc gttgccgtcg acacgcttgc gccggtcaaa ccgaccgccg ccacgtcgag
    97561 gtcatccaag gccacactca aggaattgcc cgatccactc ttgaagccga tgaagacctc
    97621 aaacgtgttg ctgctaccgc tgagaagcgg ctgaccgtta tattcggtcg tggtcgaaat
    97681 acgatcgatt tccgaacgca acgccacgaa ttcctggtcc agatacgaac gctccgttgt
    97741 gcccaacgtg ccgctggctg actgggtcgc caactcacgc atacgagaca acaggctgcc
    97801 aatcgtcgcc gccgcgccgt ccgcgacctg cgtcaagctg atgccgtcac cggcgtttcg
    97861 attggcctga ttgatactac ggatctgcgc ccgcaaggtt tcagacacgc ccaatccggc
    97921 cgcgtcatcg gccgcacggg taatccgtaa gccagatgac aaccgctcaa ctgaacggcc
    97981 caattgggct tggttgacgg ccaggtttcg ctgagctgcc agtgacgcaa cgttggtgtt
    98041 gactactaat gccatgacgt acttcctcct gaagcttccg cactactctc ggaatcgcca
    98101 gcgtccgtgc cgacgaggtg gtaaccaggt ccggtggaga tgtggccaca tccccgctgc
    98161 cccttattac cgtgttgctg tgccccttat cggtaggctc tcaggaagac ttaagtcgtg
    98221 aaggatgcgc agaaaatgcc tgtaacgagg agcagcgcgg ggcggtgtgc cctattgagc
    98281 aacaatggat attaagcagc caaacgggca tcggcgagcc ggggtaataa ttcgtattcg
    98341 agcaggtctg ccacgcggat cgcgtcggcc gtggttcgtg cgcccaagag ttcctggatc
    98401 catgggagca acgaggcaga cgacaaccct tcgacaccct gggcctgtcc ggcttccaac
    98461 atttcggtgt aatcggccag tcggccaagc caggcatcaa tggttcccac ctgggcggtt
    98521 cctgaacgca agggggccag caacacctgc ccgtcggatc gcagctcggc ggcaaatcgc
    98581 tcgatggcct gcttcgcctc gagaatgatg gtgtgcagtg actgggagat ggcttgtatg
    98641 gcccccgcat cacgaaccgg ttgattgaga aacggcggag tgagatcgcg atcgctgatc
    98701 gtctttcccc caatggtcaa tgacgtcacg atatgatgtt tggcatgcgc cttatcgctc
    98761 agcgtcgcaa gcgcgttcat catcgacgtg tcttccggta cctgtaactg ctcgccatca
    98821 agagtgatat gcatgtcagg ctcctgtaaa agaattcgtg ctgtcttctt ctctcgttat
    98881 gcggaacgcg ccatggggag ctgtcgggtc tttccccgac gcactgatcc ctgcgctgcg
    98941 gtgaaggaac ggaaactatt cgacaccgcc tgcaatcgct tgtgccaccg ccgataggta
    99001 gcgagtcggg attgcgccag tccggtcagt tcgtgcccgt catcattgtg ggtatcacgt
    99061 accatggcca cggccaggga agcggcggcc ggtgattgca tgctgagcgc aacgatctgt
    99121 tgccgctccg cagtttcaag acgctgcatc tgttgcaagg cgctaaccgg caacggacgt
    99181 ttggtcgtga gacgaaccag ctcttctgcg ttcgacacca gcttcttggc cagaggcttc
    99241 aggtgctcca acacagcgag agcgtcggag caatcgggtg acggttcgtg atcgcaagga
    99301 acccggctgg gacggccggt gaattcttca aaccagaaac ggcgccaaaa gcgaccatac
    99361 caatcgacca gcaggtcttc ccgtccggct tgcagttcgg tgtttcccag gccatcttca
    99421 tccgcacagg agcggtagat cctcacgcct gagatcgacc ggggaaatgg gactcccgcg
    99481 agtacatgca gacacaaggc agcgacctgg tccggcacga tgcgatcttt gcaggcatga
    99541 tgaaagcaga cctggtcgaa tccacaggga gcgcatccca gatccggctg caccatccaa
    99601 tgaccgggcc catagggtcc ggtttcccga aaatcgacat gcccgaccga caggtcaatg
    99661 accggtgtgc ccactcccac tgcgagatgc atggggccgg tgtcattggt cagcaggagt
    99721 cggcactggg agagcacggc ggcaagttgc ggtaacgacg tctttcccac cgcgtcgcag
    99781 agcggaccgg ttccgccact tttccggtat gtcgtttgag cgaggtgaat cgctttccgt
    99841 tcttcttctg tgccgataaa tacatacccg gctgtggttt gccggctgag agccgccaag
    99901 gtttgtccga acagttcagg acgccaggcc ttcatcggat cgctggcccc gacctgcacc
    99961 gctatccagg accgtacctg tccgccctga gttgcgagga agttgcgcgc ccattcagcc
   100021 gtatccggcg gaatcgtcag tgagagcggc gcaaacggtc cactgccact gccgcccaag
   100081 gcatagatat cgacgaggtt gaaatggttg aagcgacgct catgatgcac gtcggtcaga
   100141 taggccatcc aggggttgtg aatggtcaca tctccgtctt tcggagcggc gataccgcga
   100201 atttccttcg cgcccacata ggacgtcagc agtccgcttc gccgattgaa ggtcagattg
   100261 acgacccggt catagcgggc ctcaaccaac ggtgccgccc accgcgtcat atcgtgatag
   100321 agggtcacca catctttggt ttgagcgcga ctctcatcca ccagtcgatg aaaatcgtac
   100381 tcgacgatgt gtcgaaggtg cggcagcagc ttcgccacag gagcaaaccg ttgatccacg
   100441 acgagatcga cctctgcccc tggccattcg tgctggagcc gctgaagcag cgtgcccatt
   100501 tgcacgagat cgcccatccg ggtgatgttg atcagaagga cgcgcttgtt cataagaggt
   100561 cgcgggtctc gctgcggtat tcatccaaca tgaggaccat cagttcctca cgcttgaggg
   100621 tggcggtcgg acctttgcta cgaatacggg ctgccaggtc cttcagctcg attcgttgcc
   100681 cgccgggaca gtcttggatg agcgcctcca acggacgatc atcggcgcag cgcttcacga
   100741 gcgattcctg ctggcgctcg ccacggagga cggacccgac ccggtccggc tgagacaagc
   100801 cgatgtgtcc aagcaaatcc cgcatccgat gcacataggt atgttcgctc agcacatggg
   100861 ctcgagccgc atttgccatg gcctggcggg cagcgtgatc attcagccac tgctgcacca
   100921 atccgggaac gtcaccaaaa tcctggaacg acaccatctc ctgctccgtg aagaactggc
   100981 gtagctggga gcgatgatcg accagttgaa acgcgccgca ggcggccaat tcaaatgtgc
   101041 gtggattgac gaagtcagct tggggatcca ggcctgcgcc tgtggtggaa tgcagattca
   101101 aattgatcgc ggtcgcattg aacaccttca tgcacgtcgc ggtgtcgatc ctggccccgt
   101161 ccagctggag aacagaacgc aggtcgtctg ccccatccca ttcattcccc cacagtttga
   101221 acgaccaggg ctggcgaagc agcgccggaa aaagacgccg tcgattggca tagcccgcgc
   101281 cgacaaacga gacatcagcc ccaaaccgct gccggtcttc ctcggataac gacatcggac
   101341 aatgcaactc cgcatcggcg gccatcggaa gataattcac ctggcgcgca ccggcctgac
   101401 ggaatgcgtc gagacatgcc ccctgttgaa agacaaacca gaactcgtat cccggcgcca
   101461 actgctgcca gtacgtgaga tgccggtagt tctcaacgaa ccacatggcc gtcaggannn
   101521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
   101581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnntgc tgccagtacg tgagatgccg
   101641 gtagttctca acgaaccaca tggccgtcag gaatttcttc ttgcgcaagt gctccagtac
   101701 ctgcaatgtc atgggagcct gcgccattga gagcacgaga tcaggaggcg actcggcgag
   101761 cgtggctaag gtccattggc tcaacacatc ggccatccgg ccttgcatca attgacggtt
   101821 gcgcgggtct ttgagcgcgc ccatcacctc ataactcgcc gcatggatgc tgtgatcgat
   101881 gagctgtacc ttatgaccga gggtttccag ggcgcgtttg acgtagcccg taatcggcag
   101941 cgaccctccg taaatgggcc ccacgagggc aatggtcaat tggccaccgg cctggcgtgc
   102001 aatcccctga cgtaacgcgt cttcaacggc gcgatggaac tctgcatcag caagagcagc
   102061 cggcgtatag gacagacagc gtatcggccg gcctatcgtt gccaatgtct cggcaatctc
   102121 agccggcgtt cctggaagcc agagaatgga ctcactccag ccttcgagcg agcgagtcac
   102181 cagggcatcg tgaaactcgt cgaggttggg aagcaggact gcgagagaga catcagtcgt
   102241 cagcttcttt cgaagcgcct cgacatgata gagcagccct accccggcta cgacgaccat
   102301 ttcaccagat ttgcaggccg ctgcatgggt atccgcccag gtctgcgctt cacgaagcgg
   102361 gtcgtacgcg ctgtgaatcc agcgaccgga acgacgcgcg gacggtaggc cggttcgggc
   102421 cggctcgatc gtgagcactc cgccggctgc agatttcacc gctgccgcga gatcccggtg
   102481 gcgtgaagcg aggcgattca gattgtcttg aaacatattc atgccgccat cgattcgcaa
   102541 agggccggtg cacaagctcg ccagatgtcg gcacgcgagg actcgacagt tgcgcttccg
   102601 gatccgtcat cgaaatacgc tccccatcga tccataccgc tcctccaaag ggtccaatcg
   102661 gttgcacgac gaccctggtc gccgcacatc aatgcgatgc tttcctggat cggccaacgt
   102721 tggggctgtg cctgcgtggc atgctgatag acccaatgcc cttcaccata gggaccggtt
   102781 tcgtgcattc gggcacgcga aaaataccag ccgagagctc gagcccccgc cagcgtgcca
   102841 agatgaagcg gccccgtatc agcgccaatg acccagtggc actgctgcag cacacgcatc
   102901 aactgggaga tggtcgtacg accagtcgca tcccagacgc gaccgtggag caatgtcgga
   102961 actgaatcga gaatcgcctg cgcggtttca cgctccgtac cgcttccgat cagcacgacc
   103021 tgcccatcct gggtctgcgc aaggaactca cgaatccatt ggctccacac ggcgggagga
   103081 atacaacgat ccgcctcccc tgctccggtg accaccgcaa tccagcgccc ctggcgctca
   103141 ccgatttcgg caaggtcttg cgggagttcg acgggcggcg gctcacacga cggcgcttgt
   103201 ccgcgcggca gcactccaca catgccgcac caggcatcag cgagatgcac gcgattggcc
   103261 ccccgttccc tggcgacgtg ccggagatgc tgtgcccatg gaaggatgcg cgcctccatg
   103321 cggtcgtgct cctgttcgcg cgtggaatgg ctcaggaaca gctgcgtcat cagatggctt
   103381 cgttcatgtt gatttaacgg gtacacccgt tcatacgtcg tgtcgccgag cgatgcgaga
   103441 tactgttgca tgacctgtag tgtgactgtc ggattctctg gccacccagt ggcccaatcc
   103501 cgccattgtg ccccgtccca gggaatgact cggccgatat gactcactcc ggcaaggagg
   103561 ctgctcaacg gtgccgcaca gagaacatcc agagtgcgtt tcggataagc ctcctgcaac
   103621 gattcgatgg cggggagcgt ttgcaccaga tcacccagtc gagccatctg aatcaccaga
   103681 tcgcggggcg ccggcgatgg ctcatgcggc atggttcggt accaacgggc gttctgattc
   103741 ggccaattgt tttgccaact cgtccatccc ttcgaacgtc ggcaccatgg cgcgtaacca
   103801 gtcatattcc cgctgcgcat ccgctcgacg tcctgctctc aacagtactc ccgcgagggc
   103861 aaatcgcata gcaatattgc ccggattgcg agcgacaaac gaggaaagcc gtgtcgcgag
   103921 ggcgtcccag cgttgaagga gggttccgca tttcagcatc cagtgcatgc attcttcatc
   103981 atcggggtaa tcggcgcaaa gacctgccac gtgagaccag gcggcctcag gccgattgtc
   104041 ccccatggct gccatgacca ggccgagcat ggccttccgc ggatgtgcgc ctgcctgttt
   104101 cgcttgctcg aaggcttgtt ccgcgtctcg gtaggcattg agctgcatag ccagaatgcc
   104161 gcgcaggagc cagccttccc cgtgtgacgg ttctgcctgc agcaaggcgg tcacatgatg
   104221 atccgcttct ttcatggcgc ctgattccag tgcctgcttc gctaacgcca agcgagcctg
   104281 cgggtcattt ttcagactga tcacacgttt ccagaacgaa agcgccaatt ccagatggcc
   104341 gatgccctcg cttagtaagg cgccccaacg aagaatccat gcatcggtgg gccactgttc
   104401 gattcgtttg agcaaggaga caatcttctg ctgatccttc acggctgtcg ctcgctgcac
   104461 gtcggcgacg aatgcccgtt ctgctcgaat cgcaggatcg gtgatgaggt acagcgtgta
   104521 cccaaggagg ccatctttga gatgggtatg cacagaatag ccatcgtcaa aatgcagccg
   104581 atcctcgtcc gtcacccacc agcaacggcc ccagcgctcc cgaaaacgaa gggtgttttc
   104641 ttcctcgtgc gccttccgtc caggtgtgcg gctttccaaa tgaatgaccg tgctctgagg
   104701 ctggtagacg attttccaat tcttctcgcc gaccttgaga cagagatcga cgtcttcaaa
   104761 tccgttctta tagccctcgt cgaatccccc gacctgcgcg aatacctgcc ggcggatgag
   104821 catgcaggcg gcggtcacgc attgcagctc gcggcggcgc gagacaaagg gtgcgtctgc
   104881 cggcactccc ggatacatat ggtagggcat caggaactca cgcgagaagg cgactcccgc
   104941 atgttgaatc gtgccgtctt cgtacaacag tttgcttccc accaccgcca cctcggaatg
   105001 ggcttttacc tcttctacca gagcactgag ccacccggct tgtggaatgg tgtcgttgtt
   105061 caggaacacg aggtattcac ccttggccgc ctgagccccc tggttgcagg ctttggcaaa
   105121 tcccagattg tcgttgttgg tgatgatttt gacatcgccg ccaagaccgg ccaggaacgc
   105181 tggggtgtcg tccgtcgagt gattgtccac cacgatgact tcgtaagaca cgccctgtgt
   105241 gacctccgcc agggctgtca aacactgggt ggtgagggcc aggttgttcc acacgggaat
   105301 gataatggag caatcgaacg tcttggcctg ggcgtcggat cgcatgcctt ccaatttctt
   105361 gtgttgcgcc tccagcaccc ccgctatgcg ctccgcatag ggccggtatt ttcgatagat
   105421 gatttcggtc gtgcgccggt aggtgtcgct ggtgctgctg gtcatcgatg agccatcgcg
   105481 acgccaggtg aatgccgcgg tggtgtgctt gatgtggaga aacgggtaga tcgtcgccat
   105541 ccggatccac agatcccagt cttcgtgcgc gaagagcgat tcgtcgaaga cgccgacctg
   105601 ttcgaggcag gctttctcat gcatgacgca gagcaccggg aaatagttgc acaacaggag
   105661 atcgatgcag ttgaagtcgc gcgaatacgg gatatcctgg ccggtcacca cgtactgatc
   105721 accctgccgt acttcatgga tccgccaggc gtccgtgtac gcgaccttgt gctcgccgcc
   105781 ctgtaatgtc gtgaccagcg tctgcagatg gtccgggaga taggtgtcat cgtcgtcgag
   105841 atacgcgatg taggtgcctt tggctgcccg gattcccgta ttgcgagccg ccgccagtcc
   105901 acggttgcga tcgtgccgga tcacggtgat acgaccgtcc cggttgaggg gggcgatcac
   105961 gtcgctcaca tcgaccgtgc cgtcgttgac gacgatgatc tcaaaatcct gataggtctg
   106021 cgccaggatg ctggagagcg ccacctgcag acgatctggt cgattgtagg tcggcacaat
   106081 gaccgagacc atcggcgggc gtgtaaacga gggaacggga gaggcacccc gacgctgaca
   106141 ggcccagatt tgataaatgg gaaccaggtt cagtttatgg aaatccgccg gggtgggcgc
   106201 agggatatat cgcagcgaag gaagttcgca gtgcacccgt tccaggccga gttcgcagaa
   106261 cccttggctc gtgaagatgt cgcgcagttg cgcttccgtg acccaatcct cgaccggctg
   106321 acaaggcggc gcgatggttt tccactgttc ccacatctcc ccgcgcggtg tcgtcagaat
   106381 gacatagcca tccggcttca gaagcatgct caattctgcg acaaaccctt ctttccggcc
   106441 gtgtggaata tgttcgatga cttcagaaca gaggatgaca tcatacggag caaagtccgg
   106501 tcgactgagc acgctctggg cagtacctgc ttcgaatcgc aggtgcggaa atagccgtcg
   106561 tgcatgctcg atcacgcctg ctaccggttc gatgccttcg catgtgccat aggccgtcgc
   106621 cagattcgtc agccagccgc gtccacatcc gacatccaac atgcgaagtt gccgctgagg
   106681 gtctgtctgg cgcacgcgac ggagcagata ttccagaaag gcggcgattt tgctccaacg
   106741 agccgcttcg tcatgattgg ggcctggcga tgaccagcca cggctcttca cgaacatgtc
   106801 gatgtaaaat tggtcctgct gtttctgttc ttgaggcgtc ggggcggaat tcgatatggc
   106861 gagtcggtct accgagcctc gcggtccctg gtttaacccg tccatcacga cccctttcgt
   106921 ttcgacctgc agcgtggacg cagtcgacgc tacggcagtg ccttcctgtg ccagaagacg
   106981 acggaatgct tcgcggagag tctctcgtcg ttcggcgatg gagactggtg tgccaaatga
   107041 atgtgacacc ggacgccctt cgatcaggtc ctcccaagcc gtcaggacgg tcgcccagtc
   107101 atgcgactgt gcccaatgtt cacggcccag tcgtccgagc tcggcgcaca actccggatg
   107161 tttcttcagc aatcctacgg tggaggcgaa ctgggacagg ggaagcacca ggccccccgc
   107221 atgctcggct gcggttccgc agtccggcgt cgcgagccag ggccgaccga cactcatcgc
   107281 ttccagtagg cagagaggcg agacttccgc atgcgaggcc aacaccacga gatcggctgc
   107341 cgccagggct gaggcgacat cggcaggctc cagtcccgca agcagtcgga catccggtcg
   107401 agtcttcaga cgggctttca cggtctcgac atattcggtt tcgtgtgtgt cattcccgat
   107461 caacacgagt tggacgccat tcggcaggtg atccagcgca tcgagcaagc ccggatgatt
   107521 tttaaccttg tagagattgg cgaggtgaat caccaggaag gtgtcgcggg caatcccgta
   107581 gcgctgcctg aaatcattct tgggcgccag tgccggggtg ccgttcggaa tgacacaggt
   107641 tggaatccgg cgttcttgaa agaactgttc gtcgtatcca ttgccgccga acgtgacgac
   107701 tgcgttcacg cgttgtccca gttgagacaa catggtgcgc ccttgctcgc ttccctgtaa
   107761 cgattcagcg atctctttgt tgatggtcgg ctgaaggata aaccgaaccg gtcggtcctt
   107821 cggaatggcg agtgcggcat aaaacatcag atgcagcggg gcgcccagga gaatacagca
   107881 gccatagtgc cctgactcga tcagccgctt cacttccagc atggaatagg gactggtcgt
   107941 ttcaaagtcg gccgggaatg tcagatcgat gatggggatg ccacgatgcg attgtgccga
   108001 ccgctccgtg agcgcatagg tcgccacttc cacggcatgt cctcgagact gcaaaccgac
   108061 ggctaaactt tcggccacct tttccacgcc gccaacggag ggccaaaaat acggggtgac
   108121 aatgaggatt cgggcggcat gatgacgagg tggctgcgct gccggggtcg cgcgctggaa
   108181 ggcctgctgg tcgggcgcat tcccgatcgc tgcctcccct ccccaacgca cctcctccgg
   108241 cgccaacgga ctattggcga cgggcgttcc gcttcgcttt gcatcatagg gttggctggc
   108301 cggcggggtc tgccggaaga gccgggcaaa gatatccagt tcgttcaatc catacgctcg
   108361 cgcatctttt tcacggtcgg ccgatcgagg gctttcgatg attccatgtg cggccccgag
   108421 cagcgcaaac agtgcaagca agtcccctgt cgcgcgaaac tgatcggctt tcctacggat
   108481 gtccgaggtc agggtattcc actgccggat gtctttttca tacatcgtct tgtagcggcg
   108541 atagatggtt tccggcgtat agaccgtccc gtggcgaccc aggacatccg gatgcagcac
   108601 ccaccggaca ccccgttggc ccatctgctc gagcagatcc atctcactgg ccttcacatt
   108661 ctggaaagcg aagggtttca tggccgccgt gcgatagatc ttgatgccct ggatccggca
   108721 ggcacgatct tcatcgtaga gatgaaaaca gatcatgccg acctccgacg gggcccggcg
   108781 catgaggtcc gtcatcttgg tcgccgcgtc gaggttgagg atcatgtcct cgtcgacctg
   108841 gatgaagaac tcggttcgac aatcagcgat catgcgttga gccgccgcgc tgaagggggc
   108901 gacattgcgg atgatctcga cgtgaaacgg accgccctgc tgcgcatcga cggctgcttt
   108961 gcacgcggga tacgcgggat cgtcaaccgt gaggatgaag atcgtcgtat cgacgtggcc
   109021 aatggcttgt gtggggcgcg gttcgacaga tggagccgcg tggccggtct tggcagagga
   109081 cagcatgtag gcggcgccag cctctcgttc accatacaca ggcgtggttc ccgactgtat
   109141 ccaggcgaga gtctctacaa gccgtcgctc gctggtgtga taggtgcgca atttgtgttg
   109201 ggcgttgcct gctattcgcg tcgcgaatgt gtcatcggcc aatagacggt ccagaacctc
   109261 cgccagtgag tcgggccggc tcggtgaaaa atagaggatc tcctcccctt ccacgaacaa
   109321 actgttgttc atcggatgtc ccggcacggc gtacgacacg accggtcggc cggcggcgat
   109381 cccttcaaac acccgaccac caaaaaattt cgccagactc ggtagattga caatcgccgc
   109441 ccatagcggc aattgagtca tccactcccg gaattcccct tcgcgcactt cctgcaacat
   109501 cgtcgtgtag tgagtgagct cagcggcggg cattcccgcc ggtgtggcca accgctgaat
   109561 ggctgactgc tgcagccggt cgaataattg ttgaaacaac gtgggagccg atgggcgagc
   109621 gaatgtgagg catgatttca gcgccggatg atggatccac tgttcgcgtg gaccgtaggg
   109681 cacgccgtgg aagacgccga ctcgatgaac gggtgcgttc tgtggcgtac tgataaagcg
   109741 ttccggcacc atcggcggaa accagagagc aggaacgccg gtgcgtgcgg cggttcgctc
   109801 tacgtcgcat tcatccggaa cgagcacatg ggtcaatgca cggacctgtt gttccacgaa
   109861 cccctgccgt gcccgaagat gaggcgccca tgcgtagtcc tcctcgctgt actgcaagga
   109921 ttccatgatg atgccgacac gaatcggggc taactcactc aaccagttca gaatcgcctc
   109981 atcgaggggc gcatgaacca gccacaccca cacctgatcg aaccgttgcc ctttgagcat
   110041 ccgcttcatg tgcgccagcc aggccgtact ggaatagggc gggtcggcga tgaggggaag
   110101 cgtggtacag tccacgccac ttgcccgtaa cccttcagcg actccaaaac aggccggata
   110161 cgtccaagcg cgagcttgtt tccacgtggg aaactccagc tgcaagagaa gcactttcat
   110221 gggtggacgt ggtgtcatga ggcctttccg ttgggaccat tagccattgg ggtttgtggg
   110281 atgaccgaaa tgcccggcgg gcgcggctcc cgcccgggat gacgaggcga tcgtcaacaa
   110341 tggagcgctg ctgttcggtc ccgttggagc gactccaacc ggctgtgagc tcatggctga
   110401 ttcctggatg cgaccgaacg ctccatctcc caggctgatg agctgctcct gtgaggattg
   110461 cccgtggccg gcaaacagtt tttttgacag gaggcgtgcc acacggacca gcatgagtga
   110521 gccgccgatc atgccgtgtt tctgcagcat gggaatccag cgccagggcg cggaataaat
   110581 actgacgaat ccctcattct gcagatcgat gaggtcatga ggcgtcagct cccccaccgt
   110641 ggtgacggcc gatccatagc gtcgatattc ggagaaatcc tgcgtcatca gccgaacgcc
   110701 tttttcgccg ttgaccgcca gcttgtgaaa ctcggtcccc ggatacggca cggcgatggc
   110761 aaaattcgct tgcttgactt ctctggcctg ccgtaaaaag ttcagcgtcg ctcgcacggt
   110821 ttctcgtgtt tcccccggca atccgatcat cacggagttc aaggcttcga ctccgtaccg
   110881 gttgcagatg ccgtttgctt tcacgtagtg ctccagcggg acctgttttt tcatcgtccg
   110941 ccgtatttcg gggtcgacgg tttcgagtcc gaacgacagc cggatgagcc cgctcttgac
   111001 cagccgggcg atcacgtctt cttccacgag attggccctg gtgctgcctt cgaaggtaat
   111061 ttgcaaccct tcctgatcga tgaggtcaca aatctgtaga atgtggtctt tccagagcgt
   111121 catcacatcg tcgacaatat agaagtgccg cgtaccgaag atctccacga cttgcttcat
   111181 ctcgttgacg accgatcgcg gagagcgcac acgcatctcg gtggtcttca acgcttccga
   111241 agcgcagaaa atacatttcc acgggcagcc gcgcatggtt tgaatcgaag tgaacgggag
   111301 acgtccgcgg agcgtgccga gcttgtaccg ggacatcggt aatcgatgcc gcgcaggaat
   111361 cggcaaggcg tcgagatccg tgatgtcagc cggctgaccg gtcgagacga gttccccatt
   111421 ccgccgatat atgatcccgc gcaccgtcga caggtccttg cgttgttcat acgcgttcag
   111481 gaattgaggc caagactcct cggcctcgcc gatgaaggca tagtcgaagc agcctaacaa
   111541 cgcctgttct ttcatgatgg tgatatgagg gcctcccacg gcgatgggaa tctcgggagc
   111601 caggcgtttg atcccttccg ctacggtttt gctcaaatgg aaaaaggggc tcgtcgcggt
   111661 aaagccgatg agatcgggct tcatcgccac cgcccgctgc accatttcct ccaggggcac
   111721 ctgctcggat tcgccgtcga gaatcgtgac attgtgcccg tggcgttcag caatggccgc
   111781 caggagcgcg aggttcagcg gcggccaggt ggaattccgc cgggcaaaat ggccgaacag
   111841 tccgtaggca ccggtccatg tgggatacag taacaagacg ttcatacatc acctcatgta
   111901 atcgatgagc gcccttgcct cactaaccgg gccgccgcat cgtgtcgctc cactcactac
   111961 ggctgtgact gatccgtccg gcgcaccaca tcgggatact cgggactcat ccatccttcc
   112021 gccggttcga tgaccatgtt ggcgcggaat tcttctcgag gcagataggg atacatatcc
   112081 tcgatgggcg tcttccaacc gaagattctc ggctcgtacg tatggaactc gtgcatatcc
   112141 acatcgcaga cgaccggtcc gtcaaactgc agcacctcgt cgatcttggc atccatctcg
   112201 gcatggttcg cgatggcgac ggtcttgatg ccataggctt ggacgacctt gaggaaatcc
   112261 ggcggatggt agcccttcgg cccgcaggct tcggcacgtc cctggaaatt ggtttcctgg
   112321 taggccttgg taatgccgta aatatggttg ttcagaatga acgttttgac tttgacgcca
   112381 tagttgacga atgtctgcaa ctcctgcggg ttcatgttga agccgccgtc gccgatcgtg
   112441 cagaccactt gtctcgttgg atcggcaaac caggcgccca ttgctcccgc aaaggagaac
   112501 cccatcggag aattgccatt gttggtcagg ttgcgctggc cgtacttggt ctcgaaggca
   112561 tggttgctga cgacgatatt gccgccgcag tcacccacca gcacgtccgt ggctcccatc
   112621 ttttctgaga gacggcgcat gaacgcatag gggtggacgc gctcacgttg ggcgaagaac
   112681 tccggacgaa ccggatcgta ccgccgcttc cattccatga cgcggcccgt ccaggctgag
   112741 aaatccggca cgggtttgct gcgtcgatcg agcgcgatca agacacgctg tgtaaacgcc
   112801 ttggcgtcgc acaggatgtt gacatcgaac ggcacctgtt gaaatttccg ctggaccatg
   112861 gccggatcga tttcgaccag atacttcttg gcctgtcgag caaaactctg aacgttgccg
   112921 ccggtgatgc gtccagaaat gcgactgccg atggacagga gcagatcact gttctgaatg
   112981 ccgaagttgc ggccggcgcc accataggtc cctacccgtc cgccgtagtt ctcataatcg
   113041 gaactgatca catccagcgc gttccaggtc ggaaaacagg gtacgttcaa ccggcgcccc
   113101 aaggcccgta catcgtcctg tgcatcggcc aggcgcacgc cgcctcccac cagaatcacc
   113161 gggcgctccg cctgctggag gtcgctgatg aaacgggcga tctgctgatc gacaaccgtg
   113221 aggtcgaagc tcatggctgc gggcggctcg aagcccgtga gctgtttggc gtcgaccatc
   113281 gctttttgca cgttgagggg tatatcgagc agcaccggtc ccggtcggcc ctcttgacac
   113341 atccacaggg ccttttcgag ctcgaaccgt acgtcttcag gattcaggat catcttggcg
   113401 tatttggtga ccggcgacgc catcgcgaca atgtccgttt cctgaaaccc gatttgccgg
   113461 attgagggat cggggcgcag aaaccgcgag ttgatctgac cggtgaggaa gacacagggg
   113521 atcgaatcgt agaagcaatt gcccatcgag gtgagcagat tcatcccgcc cggcccgctg
   113581 gtcgcgatgg caaccccggg gatgcccttc actttggcat aggcttcggc cgcgaacccg
   113641 ccggcctgtt catgcatgac ggcgacatat tgggtcgcgg cggtccgtgt gaacgcatcg
   113701 atcaaatcgc cgttggccgc gccgtacacg acgaacatct tgtcgatgcc ccgttccgcc
   113761 aacgtattga tgatgaagtc tgccaccttg atcatggatg ctcctttccc tgcgctcatc
   113821 tacgccgcct gatgcgacgc ctgatcatga tgacgacggc gcacctgatg ccgacacatc
   113881 tccgctacgt gagcgacgac gtgcgagccg aacgttcgtt gcaacatggc cagatagctg
   113941 ggatggccga agtactcctg aaaggcgcgg tcgcgaaaat ccaggacctg ggtggcggtc
   114001 aggctgtcag tcggcagcgg gaggcattcg tacgcatgtt gcgaataccc gatccagccg
   114061 gggccgcctt gatcatccgg caacgtccaa tgatgctgtt tggcaagacc gtagagcgcc
   114121 gagccgggat aggccatagc acagtaaaaa ttcgcccatt cggtgttgag ggtcagcgct
   114181 aaatccaacg tcgcgcgcat gctctcgagg gtgtcgtccg gaagcccgaa aatataattt
   114241 gccgcgacat ggatgccgtg agagcggatg cgctccaccg tggcgacgat ctcccgttca
   114301 ccgaagcggc ccttctcgac cccgtcacgg acatgctggc tgccggattc gatgccgagc
   114361 cccagccagg taaagccggc gcgcgccagc ttctccagca cttcgtcctg caccgtatcg
   114421 acccgcgcgt atgcccagat gttcaggcga tagccccgtt cgatgatgcg gtcgcagata
   114481 cccatgacat ggcggcggtt caagacgaac atttcatccg gaatcttgat attcgagacg
   114541 ccgtactcgc gcacgagacg gtcgatctgg ccgatgacat tgtcgggact ccagacacgc
   114601 aacatcgggg tggtgaaggg tgcgttgatg cagcagaagg aacaggtaaa cgggcatccc
   114661 aggctggtct gaagcgaggc gtagggactc ctggcttccg ggtttccgaa acagtgccaa
   114721 ttgtgggcgc gatagcggct catatcgagc agatcccacg cttgccccgg caggtcgcgg
   114781 tcgagattcg agaagagcgg cgcgggcaca ttgccgaccg catgcccctc ctccaaatgc
   114841 cacagtcccg ggatctcgcg gagtgaatgc tgcggggcgc gcaaggcgac gacgaggccg
   114901 agaattgtcg ccggtccctc cccttgacag acatacgtat agggttcctc caacaaggtg
   114961 cgtttgggca gcgccgatgg atgggtgccc atcaccaatg tgggaatatc ggccagcgta
   115021 ttcaggatct cgcagacttt ccggccggcg ggcatgcact gcgtggacgc cgacggttgt
   115081 tgcccgtaga tgacgaagac cgccagcctg ggggcgatgg ccgcgatctg ctcggctgtc
   115141 tgctgatggg tcagcccttg agcctccgca tcaagaatgg ccacggagca actgtgttgc
   115201 cggaggtagg tggcgatcaa gcccgaccag accggcggct cgatggcggc gaagtcccgg
   115261 ctgagttcct ggtagacctg gacgcggctg ggtggtgtca ccagcaagac gtcaagcggc
   115321 ttggacatgg caccctccca gtttcttggc aaacgcgatg gtgcgcgaca ccccctccag
   115381 cacatcttct tcctgtccgc acaccgcaag tcggatacag gacgcgtagg catcgccgaa
   115441 gcagcgaccc ggcgtcaccg ccgtatgttc ttcctcaagc aggcgccggc aaaacgtcat
   115501 atcgtcgagc ccggtcctgc tgatgtcgac aaagagataa aacgccgcat caggacggcg
   115561 gcactgcaac acaccgtcgt gagtgatgcg gtcatgnnnn nnnnnnnnnn nnnnnnnnnn
   115621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
   115681 nnnnnnnnnn nnnnnnccgg cgaaggtcag atcggcatag gtttcatcgc tgaggagcca
   115741 gattcctgcc tggccgcacc gtgccaccag ctcgtgcagg atcgccggct catagacggc
   115801 gccggtggga ttattggcac tgttgacgat gatcgcccta ggctttgccg ccagagccgc
   115861 atcgatggac ggccgtgaca gcgaaaagcc gtcgcgtgcc gggagtggca cgggtacgac
   115921 atcaagtccg agatgtgcgg ctgcggccca ataggaggga aacgccggcg tgaagagcac
   115981 tatccgctcg ccgggattgc aggtgatatc caggaactgg tgaatgagca tattcgccgg
   116041 gctgatgaca acctgcgaag cggcaatcgg tttcccgctc aacgaggcgt agcgttcaac
   116101 aactgccgag cgcaattctt gtaagccgcc catcggcgca tatccgacgc gcttggcctg
   116161 cagttccccg atcgtggcct caagaatttg agacggagga gccacgcgcg gattgccgag
   116221 ttcaaggtga taaatgcggt ggccctggcg ttccagcgcc tgcgcctgat ccaaaacacg
   116281 aaacatttcc tgtccgatca aacgttcgcc gcgtgaagag aaagccggtc gagacttgaa
   116341 ctgcggcatc gacgctctct gctgggtcat cgtgcgatcg atccttgtgt ctgatgaaga
   116401 agcgaggttg ggaaataggc cgaggtgtcc ttccagattt cacggaaatg ggccagacgt
   116461 tcgggcgtcc cgatgtcgtg caacggactg gcggtgacga atccgtaaca ctgatgcgtg
   116521 acgagacgcg gcagcaggtc ccgctccaga gaccagaccg gcatgtccgg aaagagtgtg
   116581 gtcacggcgc ggtcgaacag gtagacgccg gcattatgat agttcgctgt ccgcgttcgc
   116641 ggtttttcca ccatcgataa gacgcggtca ccttctccca acgccacggc gccggtgtct
   116701 tcgcggctct catcgtgggt gacggcaatc gtcgcgccag cccgcttgcg cgtatggaat
   116761 cgcaacagcc gctcaggatc gatctcgcag aacgagtcgc cgttcagcac aagaaacggg
   116821 ttgctgcgca ccaatggcat ggcatgcgcc agtgccccac cggtgcccaa ggggacagga
   116881 tcacgcacga acagcgtttc ataggccccg cggtggcgca ggaaccagtc ctcgatcatc
   116941 tcgccgaaat gtcccgtgct gaaaataaag cggcgcgcgc cgtgacgcag gaaatgttcg
   117001 accagtaatg acacgaacgg tcgaccgtga atctccgcca tcggtttcgg acgatccgag
   117061 acaacggatt gcagtcgcgt tccgaatccc ccgcagagaa tgatcacatc acaatcggca
   117121 aactgagcca tcaagccgcc tttccgatga gggtggcctt cagccgggct gcggtctgcg
   117181 cggagctttg cgcccacacg tcatccagca tcagctgatc ttcctggtaa aacacgattt
   117241 gagtgcccag gccctcaaac ttaaacggca cctgcagcaa tccgggaagc gccagacgaa
   117301 ttcgctcatg atcctccggc ctggcgaaga gcagcatgaa tccgcccccg ccggcaccca
   117361 ggagttttcc tccgagcgcg cctgcttctc tggccgccgc ataaatcgcg tcgatagccg
   117421 gcgtcgtgat gcgcgaggtc agtcgccgtt tgagcatcca ggcctcgtgc agcatgctgc
   117481 cgaagtctgc cagatcgcgg tctccggtaa gaatcgatac accttcatcg accatctgca
   117541 gcatcgtcga taattcactc cggcgttggt tggtgcggtc gatctgctcg cgagccactt
   117601 ccgatgcaat gcgtgaaaag ccggtgaagt acaattggag atggttttga aacgccgcaa
   117661 gccgctccgg acgcataatg atcggcgcat gcccgatgtc accgttctga aaaaacgtgg
   117721 ccttgcacaa gccgccatgt gccgcaagca cctggtcctg gcatcccacg gcctcgccga
   117781 gcacatcctg ctcgacatgg atcgcagcct gagccagttg cgctttgctg ggcatgatgt
   117841 gctgcaaggc gtacagcgtg tggagtaagc ccacggtaaa ggaggaactg gatcccaagc
   117901 ccgttcgcgc cggcagatcg ccgtcgtgat gaatctccag cccgtcgtcg atattgaggt
   117961 acttcagcac gccgcgaacc gcgggatgct cgatctcctg attgttgttc accagttcga
   118021 tgcgcgaata cgcaattctg gtgcgatgct cgaagaacgg cggcaactga cggcagctga
   118081 tatagcaata cttatcgatg gtcgttgcca gcaccgctcc gccatgttcc cggaaccaga
   118141 cggggtaatc ggtaccgcca ccgaaaaacg agatacggaa cggcgttcgg ctgatgatca
   118201 tcctcgccct ccctgccggc ttgcgctgcg ctcagacatt ggcatattga ccggctttga
   118261 cgaccgtgta gcacttgatc aactcacgga tcccgcgctc caaggaccat tccggcttga
   118321 acccggtctc cagcagtcgc tggttcgaga cgatgtaatc gcgcttatcc ggatcctccc
   118381 cgatcggggc ttcgaaagac acgaactgtg gaaggactcg ctggatttct cggcagagtt
   118441 ccagtttcga gagattggcg tcgtccaacc cgacgttgta cggcctgttc ttcatatcgt
   118501 cgaagtggtc gatggcatgg agaaaggtgc gcacgacatc ccggatatgg atgtaattgc
   118561 gtttgcagtg gccttcgaac accaccaccg ctcgatcatg caccgcccgc cagacgaaat
   118621 cgttgaccag caggtccatg cgcatccggg gggacacgcc gaacaccgtc gccaggcgca
   118681 gcgtaatcgc attgccacgg tccaggacga cgcgttccgc cttcaccttc gtttcgccat
   118741 agagactgat gggacgaagc ggcgagtctt cggtgcaggg cacaccaggt tgcccgatgc
   118801 catacccgct gttggtcaca gggaaaatga tctgctgccg cggagaggac agtttgcaga
   118861 gcagttgcac ggcttcgaag ttcaccgtgt aggccccgac acggtctctg tcgcacaagg
   118921 gagccccgac cagggcggca agcggaatga tgatatcggc tttgcgcagc aggtctgtca
   118981 ccagccgctc atcccggcaa tcgccgcgca cgacttgaaa tttctcctcg gcacagcaat
   119041 ccatcaagct gttttgccgg tacataaaat tgtcgagaac ggtgaccgca tacccccggt
   119101 caagcaatcg tctggtcagc actgaaccca gatatccggc gcccccggtg atgaggacat
   119161 gtgtcgagcc tgtcgtcata gttacacgcg ctccttctgg ctgtgccact cgtgctgccc
   119221 tgctcccctg ctcatgcagc ctccaggacg atacgggaaa tgtgcaggac atcctggtcg
   119281 gtcattgagg catggttcgg cagaaaaaat ccgcaatgat ggactcggtc tgccacaggg
   119341 aaactggcct tcccgtagcg attcatccag aacggatgca gacccagatt gccggctgag
   119401 aagatgcgtg tctcgactcc ctcggccacc aacgcccgga cgatgcgttt ccgttgttcc
   119461 gggctctcgg ccagtaagcc gaaagaaatg cttgcgactt tgctgccttt cggcggccgc
   119521 tgcgtgtaaa accgcgtccc cagctgctcg agatagcgat cgtgattggc ttgccgtcgg
   119581 ccggtcatcc aatccagctt acgcaattgc tcgaggccga tgaatgcgtt cagatcggtg
   119641 gatcgcagat tgaatcccgg ttcgtagaac acgaagggcg aatgaaagtc gtccacctga
   119701 tactggccca ccaattcctg gtggcgcgcc tggtctacat ctttgctcca cccgtggctg
   119761 cgcaacatga ggagaagatt cgtgagctcc ttgtcgctgg atgagaccat cccgccttcg
   119821 atcgtggaca tttgatgccc gaagtaaaac gaaaagctcg ccatgtcgcc gaatgtcccg
   119881 acctttttgc cgtcgtattc ggctccgatg gcggcgcagg catcttcaag gagataaaag
   119941 ccatatcgat ctttcaacgt ctgcagctca cgcatccggt ggggtacacc aaggacctga
   120001 accagcagga ccgtctgcgc gtgatgacgc ttcaggaggt cttcaagatg attgagatcg
   120061 aggccgaatg tgtcgggatc ggcctcgcac atgaacggag taaatccgaa ttggatggcc
   120121 ggagcgatgg aggtgaccca tccgacgctc gggacgatga cattggtatt gcgcaacttt
   120181 cccgatcgca gcaaggcgta atacatgagg agattggccg atgatcctga attgcaatgc
   120241 accgaatagg ggcgtcccag ccactgcgac cagcgttgct cgaaatcgac ggtcaccgcg
   120301 cccttggtga gtcgcggata ggtccgcagc cagtcgatca aatgatcaat atcctgccgg
   120361 tcgatcgtat cctgagccag gcaccatcgc gggttgagct tggcactgtg tgcgtgaagc
   120421 gtcatggtag tagtccctct cgcgccaaaa aggaggcctg cgtctgtcaa cagaccaggc
   120481 accgcaccag gatactaatc aagatgtatg ccactgagga tggcagaggg aggatgggaa
   120541 accgtaggat ttcttagttg gagaactgct gcgggctttg taaccgggca aaaaattccc
   120601 agtccccggc aaccgctgta gtctaggcgg actcgaagga atgtttctga aggacgaacg
   120661 attccagcgc ttttctgacc gatcctcccc acccccggta ctcgatggtt tccttcccgt
   120721 cgaaccggaa ttccaggccg agatgcgttc cgtctgcctg cattgacacg tttcggacga
   120781 cccctgtcag attgttgacg tggcccgtcc ccacgatttc gaattctgcg cgtatgacca
   120841 tgccggggaa aaagtcctgc atcggccgct gcaccagtac cgcgcatccg gacgcgctga
   120901 ggtctgttaa caatccgccg atgcggcatg gactaccggt tggctgattg cgcaggttct
   120961 gatccgcttg taacagaacg atgggttcct gcgccgtcac gcgtccatgt ttacggagcg
   121021 gcacttcgtc cagcgtggcg ggaaaagcca gcagtaaaaa tggaaacggc tgcaactgcg
   121081 catggaggac gtccgtacga tatccgatca tttttccatt atagatgtat cgcaacagac
   121141 agggagttcc cgcagcgcaa gaaatcggtt ggccgaaatg aaacggccat tcacagacga
   121201 tccagctgcg ctctttccat cccagcaccg tggcgccgta ctgggctccg gtgccctccg
   121261 ccggaaggct gagttgcagc gagagcccca cttcgaggaa cgaagctgga tgacgatgga
   121321 cgatgagatc actcatgaag tctccccgcg cgagtcatgc aaggcataga cacacccctg
   121381 tcagccctat cggcagatgc cttcagaatc tgaagcctgt gtcacgctcg cgacatattt
   121441 ctcagtaaag accgttctca catcgaccga tagatacaag acagaaacca caccctgggc
   121501 gcactcagca caggcctttt gaggattggg cataactctg acatggcatc gacaaaacgt
   121561 atccctatcg atcagctcac cgtcggcatg ttcatcgcag gtctggatca accctggtac
   121621 aggacgccct ttctccttca caagtggctg gtatccaacc ccgacgacat cgtgcaactc
   121681 aaacggcacg gcattcagat tgtcaccatt gatacggatc gcgggttgga tgtaggcgca
   121741 gctccagtgg ccgcgccgga atccactgct ccggttcctg agccgtcgcc cgcttctgca
   121801 gaatccgtcg atgcgtcgac gaacggccat tcttcgcatg ccgcggcagc ggccgcgaca
   121861 taccgggaag cgatggaagc ggttgaacgc gtgttcaccg accttgaagc cggccagcca
   121921 ccgaagattg cggcgctcaa accggtagtg agcaaattgt tgaagcagat catcgaacaa
   121981 ccggaagcga tgatgatcca gttttgtctg gataagatgc gtcgcttcga cggcacgctg
   122041 gccaatcatg gcatggatgt ctgtgtgttg acactcattc tggccgtgga aaatagctgc
   122101 acggaaagcg acatggagtc gctcggcctc ggcgcgctgc tgcacgatat cggcttcgtt
   122161 cggctgcccc gcaacttgta ccggaagacc tcggccttga cggagcagga acaagtcctg
   122221 atgcggcaac acccgcagtt ggccgccacg gtgttatcga aaatcgactc gctccccgaa
   122281 acggtctccc aaatcatcgc gcaacaccat gagtttcagg acggcagcgg attccccaag
   122341 ttggtcaaat cgggcggact ctcgccgctg gcgcagttga tggccctggc ggatacctat
   122401 gacgatctcg tgacctcgcg ctatggccgc gcaccgctgt tgcctcacga tgccatccgt
   122461 caactgtttg tgttgggcgc gaaaggccga tacgataaga atctcgtcga agtcgccatc
   122521 aagatgctgg gcgtctatcc cctcggaagc ctgatcaagc tcaatacgaa cgaatgcgcg
   122581 gtcgtcatcg gcctcaatca tgaggaccgt ctgcgtccgc gtatccgcat catcagaggg
   122641 cccgatgggg aaattcagaa tccccccatc gacagtgatc ttcaaaacca ggcggccgat
   122701 cagccggtgc gcaccattct tcgcgcgttg gatcctaagc aggaacagat cgacctcccg
   122761 caatatcttg atgtcgccgt aggtggggca taagtatgag ccgtccatcc cattcacgtt
   122821 cacaccatcc tcaaccccct tcggggttta cgccgtcgcc tgaaatgatg ggcctgctct
   122881 gggaagcggt cccactgggg atttgtctgc tggccccgga tcacaccatc gtcttcgcca
   122941 accggatggc ggcccgtctg ctgggccgct cgccggctga ctgcgccggg aaacgatgtt
   123001 cggagcttac cggtcaaccc cttgaactga atgattcctt gcattcaacg ggggtgtgga
   123061 aattccagag cggcgccgcg gcggcatctg atgagaccac cgatatgaat gcgaccgatg
   123121 cgccggccct caccgtgatc gaatgggagc aactccgtct ttccggcatt ccctctgtgt
   123181 ccacactgct gacgctccgg gacatttcac gggaatgcga attggagcag gatcgtgacc
   123241 gtcttgccac cgtggccgaa gaaagcccct gcccgattgt cgaaatcgac cggaatggca
   123301 atattctgta tgtgaacccc gcgatggtgg aggttctgtg ccgattcgga tatgacccca
   123361 acggcaaacc ggatatcctt cccgacaatc ttcccgcgct tgtggccacc tgcctgctgg
   123421 aagggcgatc gctgacctca caggaagtag tcagaggcga ggcgtgttat agctggacgt
   123481 tatgccccgt ccccagcaat caactcgtgc gtgcctacgg aatcgacctc agtgaggtgc
   123541 atgcgacgca tcgcgcgctg aacgccacag ccgatcatct tcgtgagagc aatcgccaac
   123601 tggaccaggc gctgcagcag gcccaagcgg ccgcccgcgc aaaatcgtcg tttttagcca
   123661 tgatcacgca tgagttgcgc acgcccatga acggcgtgat cggtatggcc agcctgttgc
   123721 tggacacgtc cctgaccgaa gagcaacgct cgtttaccca aacgattcag caatgcggcg
   123781 aagcgcaact gtcgctgatc aatgacgtgc tggaatgcag caaaatcgaa gccggcaaat
   123841 tggaattgga gacactcgat ttccaactcc ggaccaccgt ggaagacgtg ctgtcgcagt
   123901 ttgcggaacg ggcgcagcgg aaaggcctcg aaattaccgg gctggtccat gccgccgtgc
   123961 ccaatgcgtt acgcggagac ccgggccgcc tgcggcaagt cttgacgaac ttcgttggaa
   124021 acgcggtcaa gtttactgaa cagggcgagg taacgctgca ggccttcctg gagagcgaca
   124081 caccggccgg cgtgatgatc aaatttgaag tcacggactc cggcatcggg atcagcgaag
   124141 aagtgcaagg gcgtctgttt caggcattta cccaggccga cagttccacg acacgaaagt
   124201 acggcggcac aggactggga ctggccatct ccaagcaact ggtggagttg atgggcggga
   124261 cagtggggct ccgcagcaag cctggcgaag gaaccacctt ctggtgcacg gccctcttcc
   124321 agaaacaagc ggtgtgttcc cctgccatcg tcccttcggc ggaactgagc ggtcgccgca
   124381 ttctcatcgt cgacgacaac gagtcgaatc gaacgattct ccatcatctg gtctcgggat
   124441 gggggatgca cgatgggcag gcacggaatg ccacggaagc catgcacatg ctggagcagg
   124501 cagcggcgaa gggggaaccc tatgatgcgg ccgtgctgga tatgctgatg cccggcaaag
   124561 acgggcttca actggcccag gacatccgcg ctcaccagca tggcgccgga gttcgcttgg
   124621 ttgttctgac gtcgctgatt cagcccggcc atgcggagcg ggcgcggcgt gccggcttca
   124681 cggcctatct gaccaaaccg gtccgccatg atcagctaca aggctgtctg cgggtggtct
   124741 tcgggatcca gcacaaggca gcgaccgcat caactgcgac cggcaagggg caacccatct
   124801 cgccgacgct catcacgcgt cacacattgg ccgaacaatc cccgcgtccg cgaattctgg
   124861 tggccgaaga caacgtggtc aatcagaaac tggccgtgcg catgctggat cgccttggct
   124921 atcaacctga cgtggtctcc aatggccagg aagcggtcac ggccttcgag cgggaatcct
   124981 atgcggcgat cgtgatggat tgccagatgc cgacgatgga cgggtacgaa gccacgaggc
   125041 tcatccgggc gcaggaagag cgaccggacg cgtcccggac gcgcgcccac atccccatca
   125101 ttgcgttgac ggcgaatgcg ttgcctggcg accgggaacg gtgcaaggcc gccgggatgg
   125161 acgactatgt caccaagccg gtgaagacgg atgatctcgg catcatcctg caacgatggg
   125221 cgccggtgaa ggctgcggca gaggtcgcgc cccccgcccc tgcccgcgac ctgagcaaga
   125281 ccgacgcgcg agtcttcgac gctggcgcca tgctggcaaa catcggtggc gatgccgaac
   125341 tgttcgatca attgatccgg ctgtttctgg accgccatag cgtcatgatg aaagaaatcg
   125401 agtccgctat cgggcaggct gacgccgcgg cgctggagcg ggctgcgcac agtctcaagg
   125461 gcacggcagg caatctctgc gcccccgatg tcgtgttgtt ggcaagtcag ctggaagcat
   125521 ccggacgact cggaacgttg acggaagccc ccagcctgct ggtgaggctg gaccgcaccg
   125581 tgcaggaatt ggtggccgtg ttatctcgcc agatcaatcc caccgactcg cagtgacact
   125641 tgcccatctg cgcgcgaaac ccaaccaggc gaacgtcgcc gtctgaaacg ctattggtag
   125701 cacaaggtaa ccaggcctga cgcggcttgc gggtgacgta ctgcaatgtg gcttagcgag
   125761 ctgaggcttg caggggctgg gatggtgact gactgggcgc tgcggaagcg gcggcaaaga
   125821 gcggatagcg ggtcggcaaa tcttccggca acaccaactg cttacacagc ctggtgcggt
   125881 ggttcatgac cagcgggcca cgcagattgg ccgtcactgc cgtgggatca tccgagggaa
   125941 tcgtcagaat cgtcacgatg gagacttcgt cgttctcctg cttctgaatt tcgatcaggg
   126001 cgtccgtcgt gatcgtgacc tggtaatcgg gcttgaagag cgcaggatcg agaatgacga
   126061 aggcgagctg tggttcctcg acacattgca gccacttgaa cggcgcatcc gtatcatggt
   126121 cgagcatgac gtatttggtc cagtcgggaa agcccagaat gccggatggg aacaccaaca
   126181 acgtgtcgtc gttgacttcg aaggtgccga atctggtcga ctgacacttc atggacggtt
   126241 ctcagctccc gcggcgtcct gttttattgg acagttgacg gaaggcttcc agaggaatga
   126301 ctccggggcc tgcggcaatg cgattctcgt cttgaatcct cgcatgcact tcatcgcgat
   126361 gcacttgcac attgggcggc gcttcgattc ccagtctgac ctgtccgcct ttgatgccga
   126421 gcaccacaat gcggacatcg ggaccgatgg tgacgccctc tccccgacgt cgtgttaaga
   126481 ccagcataca agccttcctt ggcgtgtgaa tacgggtaca ttgggtatat cggtacagga
   126541 gagaatgaac ttgagcgttg gttaccgcag atagttgatc aacgaggagt caaaaatctt
   126601 actgaacgtc tggctggcgg cctgcaccgc aacctgctgg aggctcaact ggctgatggc
   126661 tgtagcgagg tcggcatcct gattgtcgga aatggccttg gaaatcgtca gggtcgccgt
   126721 atccagcgcg tcgtgggtga cctgcaggcg gttagccaac gccccgaccg tcccctgcgc
   126781 gtcgctgatc tgtgccgtcg ccaggtcaag attgccgatt cccgtttgaa tacccgcacg
   126841 attgttgctt tcgagcgccg tgagcaaatc ccggagcgaa tcgaacatgt tcgtggttcc
   126901 gccggtaaaa atgctgctac ccggaacaag aatttgcacg gtctggtttt cgcccaccga
   126961 gatggactgc gtttcggtgt tgccctgata ggtcaccgta tcaccggtgg taatgacgta
   127021 gggagtcaca ttggttttgg tcccgccgaa taccgcctgc ccggccactt ccgtattgcc
   127081 cagttgcacc agctgccgtt ggagctgccg gacttctttg gcgatcgact gacggccttc
   127141 ggcggaggtc gtatcgctgc tggcctgaat ggtcaattcg cgtacccgcg tgataagggt
   127201 ctgaacctgg cctagtgcct ggtcggcggc gttgactcgc gaagtcccga aatcgatatt
   127261 acgaatccat tgcttggtct gcgacagcgc ggacttgtcg aggacgatct ggccatagga
   127321 gctcggatcg tcttcgggag tcgagacccg tcgctggctc gagacctgtt cctgagaggt
   127381 cagcatttgt aaccgggagc gttgcagatt gccgagcagg gtgttgtaca tctgttggtc
   127441 ggcgactctc ataatacctg ctccgggtga actgaatgac ggttaccgtt tcaaggacaa
   127501 gatcgtctgc agcatttcgt cgctggtggt gatcagcttc gaggcggctt gaaacgcccg
   127561 ctgatacttc aacatattga ttaactcttc gtccatcgag acgccggaca cttccgcccg
   127621 atgggccaac agttgatcgt gcagaatctc ctgcccttgc aggtcccgcg tggccccttg
   127681 cagggttgct ccgaagctcc cggccattgc accgtagtag ctttgaaacg tcgtgtttcc
   127741 caagcccgcg accgatgccg tctgtaaatt cgccagggcg agggcgttga cgttattgcc
   127801 cggcacgccg gccgcagtcg aggacgcggc gatcttctgt cgatccgtca gcgccatgct
   127861 gatcgtgccc gccgtagttc ctgtcgccgt gaagaagtcc tgcgtcgtcg acccgtccaa
   127921 gccatacccc aatttatgct gggtgttcac ttgcgagacg agttgcgccg tgagcgtgtc
   127981 gagagaggtt tgcaggccgg tcgctgtggt atcccgcgca tcgagcagac ctttgaggcg
   128041 cccgccactg atcgatgagg tgatatcggt gttggggccg gttccgccgt cataccgcac
   128101 gtcgagcaat ccgttgttgg tggcatcggg aacgcccgtg agcttgaagg ccgtgtggtc
   128161 tgtcacaagg acctggccga ccccgacaaa cacggtgacc tgcccgtttc catcttcgat
   128221 tgaagaaata tccaccaggc cggcaaggtc attcaggaac cggccacgtt ggtctcgcag
   128281 gtcattcgcc tgttgcccgc ccacttcggt caacttgatc tgggcattca ggtccgcaat
   128341 cttactcgcc agcgcgttga tgtcattgat ggcacttccg atttgcccgt cgagggagat
   128401 tcgttgggtc gacagctgcg atgaagcctg gttgaggact ttcgtcagcc cgtcggcctt
   128461 ggtcaggagc accgtccgcg ccgtcagatc ggcgggattg gtcgcgacat cctgccacgc
   128521 cttgaagaat tcgttgagcc ctgccgcgat gccttgatcg ttcgcatcgt taaacagaat
   128581 ctgaatttgt gagagagcct tctgtgaggc gccgaattgc cctatccgct catttgagtt
   128641 caacaattgc tgttcaacaa agctgtcgac ggaacggcgg atttccgaga cctgcacgcc
   128701 ggtcccgatc tggccggggc gtccgttttc cggaagggtc tcggtgagga cggcctcctg
   128761 gcgcgaatag ccgggagtgc tgacattcgc gatgttttgc ccggtgacgg acatcgcgcg
   128821 ctggaaactg gccagcgcat tggaacccac tccgaataat ccgtttagtc ctgacatacg
   128881 accactcgtt atcctttggc tctcaccaga ccggcgcctg ccgggaccgc cgtgccggct
   128941 gacgaataca gcgccgccga ctccggagct ctttgccagc gtttcagggc gccttgcaaa
   129001 aattcaagcg actgcccgat gagtgcggca ttgaatcgat tcaagcgatc agtctcgccg
   129061 atcgccgcaa gcagcttggc ttccatcgtg gtgcgcgcgt cctgtcgaga caattcagac
   129121 gaggtctgct gacgccgccg ttgctcgaaa tcacgaatct catctagaag ttgagatttt
   129181 cgcgtggtga cggaggtgaa ttggccgaag gacagggatc ggatcgcatc ctgttcctcc
   129241 agcagcaagg actggaacgc gagcattttg tcgagcatgc cccgcacgag catgtctgat
   129301 tcagtgggag tagtttgcga gagcgtcgac accgtgcttc ctcctcgaca gtaacgttcc
   129361 ggcatacgag gacagcgagc gaagggtcga gccggtgaag cgactcgtta caggaccgcg
   129421 tccgtcaaga cgttacgaat gatggcatcc gcaacttttt tgccgtcgac gttataggtg
   129481 cccccttcga ctgactgctg gatctggccg actctggcgt cacgttcgtg atccggttgt
   129541 tccgctgcgg ccctcagacg ttggagttcc ttggcccgct cggaaatctg tacgcggtct
   129601 tgcgacggcg tggtctgaga tgcgtttttc ttgttctgtg tccggtcagt ctcctgaaca
   129661 cctaagagaa ttttcgcgag atctgcggcc cggccattgt gagagatctc catgactgct
   129721 tctcctcccc tttgcagggt gttccgtagg ctttccccta gtcgagtact ctatcggcga
   129781 ggtcggcctg gaactttagg agaaccggtc gatttatttg tttttttcga cgtacgcatc
   129841 cacgaaggcc gtaaggccaa tgcctcccgc ctgtgtcgcc agcttggcaa tctcctggtc
   129901 gtagaaggag taccagacct gctccccctt cctgtccaac aggccttttg gcactgtttc
   129961 cctcatcttt ccaataagat aggatataaa gtaggcttcg aactcctgtc cggccttatg
   130021 catcgcttca gtggatttct gccctgcctt ctccaggcct tggactcgct cgaggcctgc
   130081 gggctgagtc gcattcatct gggccagatc aagctggccg ctcaacagat tcttgatgtc
   130141 catgatggtc cagacctttc ttacacgatc tcaagattcg cttgaagtgc tccggccgca
   130201 cgcagcgccg acagaatcgc gaccaggtca cgtggtgtga cgccgacggc attgagggcc
   130261 cgcacgactt ctccaagggt aacggtctgg tccacgacga tcagccggga ctgctcttcg
   130321 gccacatcgg tctgcacatc cggcgtgact gtggtctggc cttgggtgga gccgatcaag
   130381 ggcgcaggag gttgcgagac gttgagggta ttcttcacgg aaatggtgag attaccatgc
   130441 gagatggcgc aggtagagag gcggacatgt tcacccagca ccaccgtacc ggtgcgttca
   130501 ttgaccacca ccttagccgc cacatccaca ctcacatcca atccttccat cgtcgcgata
   130561 tattccacca ccctcccctg gaaggtcgac ggcagcgtgg tcttgacgag gcctgcattg
   130621 accgggacgg cagttccttt tccaaatgtc ccgtcgatgg cttcggcggt gcgaatggcg
   130681 gtcgtgaaat caggatgccg caggagaacc gacacggtat cccactggtc gatatcgacg
   130741 accaattcct tttcgacgat cgccccggcc ggcacgacac ctgcggcctg atgattcttg
   130801 gtgactgtgg cgccgcccgc gccgccggtc cctcccaaaa atccgccgat cgacacagga
   130861 ccctgcgcga ccgcaaacac ttgctggttc ggcgccttca acggcgtgag gagcaacgtg
   130921 ccgccttgga ggctcttggc gttcgccatg gaagatacga tcgcatcaag cgtcatgccc
   130981 ggtttgacga acggcggaag cttggccgtg accatcactg acgcgatgtt tcgcgtgagc
   131041 aactgaatcg gatcaatgac cagattgatg cccatcttgt tcagcatgga catcatggcc
   131101 tgaatcgtga actgaccgcc gatgacttga tcgccggtac ggtccagacc aacgaccagt
   131161 ccatatccga tcaattggtt ttcccgtacg ccttcaatcg tggcgacatc tttgacgcgc
   131221 acagcatggg cgagcgaagc gctgaagaag gagatcgtca ggaacgccag catgcccacc
   131281 gcggtgcggc gaaaccaggg actcatctgc tgtcgaggtt ccgagacggg agccggtttg
   131341 ggaggcggcg gcgtccatgg acgggccaga agctctggat ccaccgaggg cgtccgaagg
   131401 acgccgctcg acagcatgag acgaaaacac tgcataatca tcgcccgttg ttgtttgcgt
   131461 ggcttcgtca taatgactcc tgtctcgctc ctgtcggtcc tactgctcgg tcattagaag
   131521 ggatagaccc aatccagaat cctgacgaac cagcccggcc gctgcacatc gtccaccact
   131581 cccaggccgg aatattcgat tttcgcatcg gcaatggcgc tcgattgcac ggtgttcttg
   131641 gtgttgacgt cgacacggcg cacgataccg gcgatcgtca tgatctgccg ctccgagttc
   131701 acggtgactt cgcgccgtcc ttcgattcgc aaatcgccgt tgggcagcac ttcggtcaca
   131761 atggctgaga tggtgccggt caacgtgtct tcgcgattgg tggcgccttt gccgccgaac
   131821 ttatttttgg cgctggcgtc gatgccgaat ccccgcttgg cttctccacc gagtcggata
   131881 cccggaaggc cgagataccc catgcctgtg ccgccgagtc cattggacac cgtcgaatcc
   131941 ttttccgcgc tggtgtcggc gctcttcgat cccttgtgtt tctcggagat cagaatcgtg
   132001 atgatgtccc cggcacgcat ggcacgcaga tcttcataca gataggcccg cccgttctcc
   132061 tcctgccaca gcgagccggt cgtcttgggc ggcggcattt tggccaactc cgctttcgcg
   132121 ggcttcgcgg cagacgaagt cgaacagcct ggcagggcgc agagcgcaag cccgcagagg
   132181 atgaatccga tcgtctgata ccttgtggat gatgggttag aagctgacac ggaccacccc
   132241 cggaccgacc acggtcgctc gtagatcctt gccggaatca acattggaca ccgtgatggt
   132301 ttgacccagt tcaccgtgcg acttcgtcac acctacggtt tgaatggaga gtcccccctg
   132361 ccgggcttcg atcgtcaccc gatcgccctt atgcaccgca aacgggcgac ggagggaggt
   132421 cagccgaatc gcgttttgag gcggcagcgg gcggatcgcc gctttgccga cgacgtctga
   132481 cggattcatg gcgaacggtt gcttcaggtc gtacagcacg agacgttcgg tcgccacgtc
   132541 gtccgcagcg atttcctcat cgaccttaat cgaacgaacc gggactacca cttcgacgat
   132601 ggcagcgaca tccgctgtgg cttcgacggt tttgataaag cggccgttga cggtcaggtg
   132661 aatctggaac actcgccggc cgagcggctc ctcggaatga ttcgcgctga cttgcagatc
   132721 catcgtgccg gaaggcacca cgatcggctg ttggggatcg cccagcgcca cctggcaatc
   132781 gaccgcgcgt ccggcaagtt cacgcttgac gaagtcgcgg ataactccac gaatctgttc
   132841 cggatagatc gtgtgtttcc cgcgagccag tggaagactg tgcgcaccct gcacgagggc
   132901 ttcatgcacc cggaacagag gccgaatcgg agcccgctcc cctgccattg caggaaggac
   132961 ggcgctggcc aacaggctta tggttgccac agagataagg ccggctcgat tcacaggtgt
   133021 cacccctggt tcaaggtacg gcgccgatta ccggcgcagg ttattcgcga tctgcatcat
   133081 ttcgtcggac gcttggatcg tcttcgagtt aatctcgtaa ctgcgctggg cgatgatcat
   133141 gttgaccatc tcttccgcca gattgacgtt cgaactttcc agaaagccct gctgcaacgt
   133201 gccgaagccg gtggaaaatc cgccggttcc ctgctgcgcc ggtcccgacg cgaaactgtc
   133261 gaggaacaaa ttgccgccca ttgcgacaag accggaggga ttgtcgaaac gcacgagctg
   133321 aatctgtccg acctgcgacg cctgggtcac accggggagc aagacggaga cggtgccgtc
   133381 ctgcccgata tcgattttga gcgcgccgga agggatggta atgaccgggg tcaactgatc
   133441 accgtcgccg gtgaccagat tgccgacgtt atcgcgcttg aaggatccgt tacgcgtata
   133501 catgatcgtg ccgtccggac gcgcaacttg gaaaaatcct gcgccgtcga tggccagatc
   133561 gaggtcgttg ctcgtctgtc gcatgttgcc ctgcatccat tccttggcaa ccgtaatggg
   133621 acggacgccg ccgccgacct gtacgcccac gggaaacacg ccgacgttcg acgcgttcgt
   133681 gccgggcaac cgttgaatct gatacagcag gtcgccgaat tccgcacggc tgcgcttgaa
   133741 cgcattcgtg ttcacgttgg ccaggttgtt ggcgatcgtg tcgacgttga gttgctgggc
   133801 cgtcattccg gtggcggccg tccacattgc acgaatcata caactcctcc tattgcaccc
   133861 ggccgagatc ctggatggcc gtatccgtca tatggtccag cgtctgaatg agcttctgcg
   133921 ccgattcata actccgcatg ccctgaatca tcttcaccat ttcgctcaac gaattgacgt
   133981 tcgattcttc gatatggccg gactggagct gcggtttctt cgacacgctg ggcttcccgc
   134041 cggtgaacaa gccttccgcg aatttctgcg gcatctcgtt agggggaaat tcgacgacct
   134101 tgatcgtgcc gatcgcgttg ccatcgactt ggatgccgcc ctcggcgttg atctgaatgt
   134161 tgccgggcgg cactttgatc tcccctttcg tgcccatgac cggatgtccc agattggtga
   134221 ccaaacgtcg ttggccatcg agggagaata ttccgttgcg ggtatagcgc acgccgtcag
   134281 gcgtcttgac ctcaaaaaat ccgtcggtct gaatggccag gtcgagcgga ttgccggtga
   134341 tgcggatccg tcccggctcg aaggtcgtac gcatgccgtt tgcttcggta aacacgcgct
   134401 cggtggggcc ggccggtctg gttgatatcg tcgaggtgat gccgctggat gcggcgccca
   134461 tacccaccga cccgccacgg gccaggaggc cgcgaaaccc ctgttggtcc tgtttgaatc
   134521 cggctgtatt gacgttcgcc aaattgttgg cgaatacctg gagctgtttt tcttgggcga
   134581 ctgcgccgga aagtatggga tagatagctc gattcatatg gtgtcggttc caacccttct
   134641 ctctgttcac agggagagtt agcaatcgac atgccattgc tgcgggaagc gctgcatcgc
   134701 tcgcaccgct accgcagact gagaaaatca ctcatgattg ccgatagatg gcgacggtgt
   134761 gctgcgtaaa cgcgcgcagg cgcagcccgg tgcggtcgac gagagctgtc aaagatgctg
   134821 gcgagtggaa gtctttaccg caggctggga aagtcctgcc tacctgagca ggtgccgagg
   134881 atgagtgagg gagaattagg ccgcaatcgt ggaggtggaa tccgtctgtg gctgagggag
   134941 cgccgtctcg atgccggaca ttcccgacgc gtcggtccgc gccatctcaa gggctcgtgc
   135001 agcagcctca agcaaggcat tggggtcaag atcgtcccgc ttggaaagcg cgagaccaat
   135061 ccggccggtg aggaacactt catgatgatc gagggtaatc ggcaaggcga tggcgccttg
   135121 cattttcctg gcgagcagca acaggttatc cgcatcggtg atctgatcca ctaacacggc
   135181 aaacgtccgt tccgctattc gcgccacagt gtcggtcgtg cgcaaggcgc ttttcacgcg
   135241 ggcggcttcg atccggtaca tgagatgacg gttcagttct gcagggcttt cggcggcggg
   135301 cgtgaaataa tccagctcga tgatgaggac cgccacctgg cgtccatgct tctgtccacg
   135361 gatcagggct tgattcagga gcgagagaaa cagacgattc agggggaggc cggtgaccgg
   135421 atcgtacgtg gtcttgctgc cactttctgc ggcgctccag agcggccgca cagcggaaga
   135481 gcgacttcgc ggagtccaga aggtcgcccc gaaaatcatc agcgtgaagg cgacgccgat
   135541 cgaaaccatc acgggatagg ccgttaatgc ggagatggtc aggagaccaa tggccgcggt
   135601 ccaatacaag ccgcctgcca taaacaggag acaggccaat acgccgaatc gggcggcatc
   135661 ataggatcgg gtgagcgcgt cattgtccga ccaggcatga tgatggtcgg gctcaggctc
   135721 aacggcagcg ctcgactcgc cggttactga tggaggcacg ctcatacgcg cgaagagaac
   135781 tgataggttg cccaatggct attggggttt agagcgtatc ggacggagcg gggggaaact
   135841 aaaggcggtg ggtcggtgtc actgaagatc gttcatagaa ccgacaacaa ggaggagcag
   135901 tggatgcgaa tggccggttt gacatctaga catcaaccgg ttcaagccgg gccttaagat
   135961 gaagaatggc tttcgaatgg atttggcaga cacgcgattc cgtgactttt aaggcctgcc
   136021 cgatctcttt catggtcaac tcctcgaaat agtagagtga cagcaccagg cgctcctttt
   136081 caggcaagtc ctggatcgcg gcttccagca cgtggcgggc tcgctcattc accagcactg
   136141 agagcggatc cggctgattg gagtcggtca acatgctgat gatcttgtgt ccatccgcat
   136201 cctggactcc gaggtcatcc aggctgatga ccacggcgcc tcgcgagcgg gtcaggaact
   136261 cgtccaactc gtccgcagac attttcagtt ctttgccgac ttcctggtct gttggcggac
   136321 gaccgaatcg atgcaacagc tcggagtagg ttttttgaag cagggaaatg cgttcatgaa
   136381 ccgagcgcgg aatccaatcc atcgatcgga tttcatcaag catggcgccc cgaatccgga
   136441 attccgcata ggttttgaac ttggcctcgc gggtcggatc gtatttgtcc atcgcatcca
   136501 tgagccccat gatgcccacg gacatcaggt cctccgcatc catgtaggcc ggcagccgga
   136561 aagccaaccg atgggccatg gccttcacga catgcgtgaa ttcctgaatg acccgctcac
   136621 gatccgcttc cgcaatcacc cggcgcgagg catttccggt cgcagacatt tttcgtgctt
   136681 ccatcatgcg agttcagtcc tttcagtcag tgcgttcgca agagttgttg ccagaggaac
   136741 tgcactgtgc ccttcggaag cgccggaggc gtcaactggg ccaccgcttc agtcagctct
   136801 cggaatgcgc ggctggccgg cgcgtgagga aacagatcga tgacggcacg ctgctgggac
   136861 accgccatcg gcacatagtc gtcctgcggg atggcgccca ggtagtcgag agaaatgtgt
   136921 agaaagcggc tgacggccac ttccagctta cggtagatgc gtgcggcgtc acgcggtgac
   136981 ttcaccatat tgacgaggac gtgaaagcgc cgttcacggt attgccgcag caagaccttc
   137041 atcaacgcat aggcgtccgt cagcgacgtg ggctccggag acacgacgac cacgatggac
   137101 tgggcagcag ccgcgaagta cgtcaccgtt gacgagatgc cggcgccggt atcgatcaac
   137161 agcacgtcca tcgtggaggc caggcgttcc agctcttcct gcagaataag ctgctgcgct
   137221 tcggtcaaga cagtcagttg cgaaatgccg gtgctggcag gaagcaccac gatcccgttg
   137281 ggaccggtca aggcgatctc ctcgagccgg cacgttttcg ccaggacatg ttccagcgtg
   137341 tatttgggcg tcagccccag gagaatatcg acattcccca agccaagatc ggcatctaac
   137401 accagcacgc gtttcccggt ctgggcgagg gcgatggcgg tgttggccac cacattggtc
   137461 ttccctaccc cgccctttcc gctcgtgacg gtgatgacct gcgtgcggga gggaccgaca
   137521 ctgccgtcaa acgtgttcag ttgcggatcc aaaatgtctg gttcgatcgc catcgtctct
   137581 cccctgttat tcgctaccgt ctatcgcgtg taggtcttga tgcctggcac aactgccggt
   137641 gcggcctgcc tgatccatgg ctggccattc tgctctcccg gcgtccgaac ctgcccaccc
   137701 agcagcaggt cgcccaagcg gttgacttgc gcctggacta agtcgtcggg cacacgttga
   137761 ccggtgcccc aataagacag cgggatgccc gtccgatgcg tggcttcaaa aattccgccg
   137821 tacccggtcg tttcatccag cttggtaaac agcagtcgca acgagggcac gtccacacac
   137881 tggctggtac tgaccacgat atccggcaca cgcgtgccgg cggccaacac gagatgaact
   137941 tccaggggaa gggccccgtt cagcaaccct cgccaccgct gcgccgcgat cggttcatag
   138001 gggttgaatc ccgccgtatc gatcaggatc aactctgctt cacgcgcttg cgcgatagcg
   138061 gcgcgagcgt cctcgcatga cgatgcgacc gccagctcga ttcccaggac ctcggcgtac
   138121 agccggaggt gttccaccgc cgcgggacga taggtgtcca tggtgatgag ggcgacactc
   138181 cgctgttcaa cgatgccgta gtgcgtcgcc agcttcgcga tcgttgaagt tttgccgacg
   138241 ccgctgggcc cgacaaacat cgcgatcttt tgctcgccgg cgttgctcag caacggaccg
   138301 gcggtcgaga cacgatcgag cagtaccgtc cgcaaaagct ggagagaaga attgcgctgg
   138361 gaggtcccct gttcaaccaa cgtctcgcgc aactctcgca aacaggcttc agcagtggca
   138421 tgctccacgc cttgggccag gaggtcttca tagacccgtt ggaatgattg gaaggttgtg
   138481 ccctgaccgt ccttggtgac gggggaagac tttgccgtgc gggaaagttc ttgaggaaca
   138541 aaagaggcct ggcgggaagc agggcgcggc tggtcctctc tcttctctat ggcgccttga
   138601 agtgttttct ggaaccgtga ctcctcggcc ggcaccgcgg gagcttgtgc gacagccgga
   138661 gcggaacgtt catcttcgcc cagtatgggt gcagattccg gcaccgcggc atcgtcttca
   138721 atcgccgcca tcacttcgag catcgatccg cccaggaggc cgaacccgtt atcccaggat
   138781 cgcacgcgct tcgtcgacaa aatgacggca tccggcccca gcgtatcctt gatggagcga
   138841 atggcctcat gcattgatgc aacgtgaaag gtccgtacct tcatgccaag ctcctcgtgt
   138901 caccgccgtc gagatcgaga cgaactgttt ccatagcctg taatcgcgtc acgctatcca
   138961 cttcgttcaa tcccaggatc ggtaccgagt gcaaaatgcg gtccgtcaat ttccgcagat
   139021 gcctacgtag tgaaggggaa caaagaatca ccggttgatg tcctcttccg accatgcgct
   139081 ccgcggcctg cttcaatgca ctgagcagtt tctgtgccac cataggatcg gggatccatt
   139141 gatttccctg cccgactgca ttggcctgat cggcaagggt gcgatccagg cgcgggtcga
   139201 ggccgatgat cggcaacgag ccgtccggcg cgagatattg tttcgtaatc gtccgtccca
   139261 gggcctgacg cgcgacttcc gtgagaatat ccgcgtcttt tgtgctcgcc gcatggtcgg
   139321 cgagggtttc caggatcgtt cgcaagtcgc gaatgggcac gccttctcgc aggagatgcg
   139381 acaacacgcg taccagcgtc ccgagaggaa tcaagttcgg aaccacttcc tcgaccagct
   139441 tagggtgatt cttgcctagc tgatccaata agccctgcac ttcctgccgc cccagcaact
   139501 catgcgcatg tcgcttgatg agctccgaca gatgtgtcgc gatggcggac ccgggatcca
   139561 cgaccgtgta tccggccatc tgcgcctgtt cacgttgttg ctcgggaacc cagagggctg
   139621 gaagtccgaa cgcaggttcc ttggtcggca acccatgaat gattccacgt tgagcggtcc
   139681 ccggatcgat agccaacaca tgggccggca tgacctccga cttagccagc tcaacgccct
   139741 tgaggagtgc ggcatattcg ttgggcctga gttgcagatt gtctcgaatg tggatcggcg
   139801 gcagaacgaa tcccatttgt tcggcaaatt gacgtcgtaa gcctttgatc cggtcgagca
   139861 aggcgccacc ctgccctcca tcgaccagac cgatgagtcc gtatccgacc tggacttcca
   139921 tgaggtccag cggcacgacc tgggtagcgg cttcctcggc tttgacctga ggggattccg
   139981 gttcgggagt tgcgaccgcc gtcttctggt gctcattgag ttggaaggcc atccagccgg
   140041 tcaaactacc gagcgccaga aaggccagat ggggtaatcc cggcaccaat cccatggcga
   140101 ggagaatccc ggaagctgtc ccgatggctt tcggcgagat caggacctgg cgagtgattt
   140161 cgaatccgag gttgacctcg gaggctgcgc gggtgatgac gataccggcg gcggtggaga
   140221 cgatgagcgc cggcacttgc gcgacgaggc cttcgccgac cgtcagcaag gtgtacgtct
   140281 gtgcggccgc cgctaccgtc attccctgtt gcagcacgcc gatcgtcaag ccacccaaaa
   140341 tattcacgag cgtaatgacc actgccgcca cggcatcgcc acggacgaac ttgctcgaac
   140401 cgtccatggc tccgtaaaag tctgcttcct gggcaatttc ctttcgccgc tggcgggctt
   140461 ccttgtcatt gatgaggccg gcattcagat cggcatcgat ggccatttgt ttgccgggca
   140521 tggcatccaa ggtaaaccgt gcggcgacct ccgccacgcg tcccgcacct ttggtgatga
   140581 cgacaaagtt gatgatcacc aaaatcgtaa agacgaccag accgacggta tagtttccgc
   140641 cgacgacgaa attcccgaat gcgcgaatga cttcgcccgc cgcggccgcg ccttcattgc
   140701 catgcaacag aatcaggcgg gtcgatgcga tgttgagcgc cagccgcagc aaggtgacca
   140761 tcagaagaat ggaggggaag accgaaaact ccagcggacg ccggacctgc atgccgacca
   140821 ggagaatgat gatcgacagg gtgatattga agctcagcag taagtccaga aagaagcgcg
   140881 gcagcgggac gagcatcacc atcagaatgc cgaccacgcc cacggacatc agaatgtccg
   140941 gatgcttcac gagggatgtg ctgggtatcg aggtattgtc cttcgccatc tccgctccct
   141001 accggctgac tatgccggcg gcaatttgcc acgcacgcga tacacaaagg ccagaatctc
   141061 ggccacggca cgatagaggt cttccggcac ttcccggccc acttcgacca acttgtacaa
   141121 cgtcctggcc accagcttgt tttcgacgat catgacgcca tgctgacgac cgatttcccg
   141181 aattttttcc gcgatgaatc cagcgccctt cgccacgaca atcggtgcgc ccatcgcctt
   141241 tgaatcgtat ttcaatgcga ctgccaggtg ggtcgggttc gtgatgatga cgtccgccgt
   141301 gggcaccgcg gccatcatgc gcttgcgaga catctcgcgc tgggtgctgc gaatcttcgc
   141361 tttgagcccg ggatctcctt ccgcggcacg actctcttcc ttgatttcgt cgcgcgacat
   141421 tcgcagacca cgttcccatt caaagcgttg atacccgtag tcgagggcac cgatgaccag
   141481 agcggcgccg ctcatcatga gtgcggcctt gaaggtcgcc caccccaccg tgggcagcag
   141541 ggtttccatg ccgaactggg ttagcggcaa aaattggagc atatcctctt tgattgtgag
   141601 gtagccgacg ctgccgatcg cgaggatctt gagccaggac ttcaccagtt cgctcaatgc
   141661 gcgcaccgaa aacagccgcg aaaagcctcc caccggactg atacgcgacc aatcaatact
   141721 gaggccgtct tttctccaca ggaagccggt ttgcatcaag ttggcgccca cacctacgac
   141781 agcgattccc gccactaccg gtcccagcat cacaaacacg tcgattccga tctggcggag
   141841 aatcaaatgc aggtggtcga gactgagtgc ccgaagtgtc gagtcctcca tggattggct
   141901 gagccagcgc tgcaaggaat ggcggagtcg ctccataatg ccaggcgtca tccagtagag
   141961 cgccgcgaaa cttcccaata aagcgacggc catggcggca tcgcggctga gggcgatttg
   142021 acctttcgat ctcgcctctg ctttgcgttt cggtgtggcc tgttctgtgc gattttgggc
   142081 gctgtcagcc atgccccaac cccttcagga gactcaagat cgtctccacc aggttctcga
   142141 attctttctc aaacagcgac agcgtaaagg gcatggccaa actcatggcg aacaggcccg
   142201 ccccgatcgt gatcgggaag ctcaggacaa agacgttcat ctgcggcacg gcgcgaccaa
   142261 ggatggcgag gaccgtattg acgatcagca gggtggcaaa gaccggcgcc gccatcttga
   142321 gtgcgacgcc cagcatgttc tgggctaaat gaataatgtc cgtggcgatg ctgtcggaca
   142381 gtttggcgcc gaagggcggc acaaattcgt aactcatacc gatggcatgc acgaccatca
   142441 ggtgtgcatt gagcgaaaga aagaccaacg agccgagcgt cagttggaat tgcgcgatga
   142501 tgggtgcgtt ttggtggctc atcggatcaa acatctggat cgcgctgaac cccatctgcg
   142561 tgccgaccaa ttctccggcc acctgaaagc cggaaaacaa gagacggacg gccaggccga
   142621 tggtcaggcc gatcaggaat tcgctgccga tgcccgccac caccagggcg ggatcgttcg
   142681 gaaaactggg caattgaatg atcggagcca gcacgagccc cagcattgtc actaaccccg
   142741 ccttgaccgg catcgggatg gtcaacgtgt tcagaatggg aaagacgctg atgataccgg
   142801 caatcctgac caacagaatc gaaaacgact gaaactgtgg caatgcgagg tgcaacgttt
   142861 gcgcgacgtt catgctgtgg acgacctatc agtgaatcaa cgtcggaatg ctggtgatga
   142921 tatgagtcat aaatgcgatg agcacgccca tcatccacgg cagaaacaac agcgtcgcgg
   142981 caaagacggc caacaccttc gggacgaacg tgagtgtcgc ctcattgatc tgcgtcatcg
   143041 cctgaaaggt actgaccatc aagccgacca cgaggctcag gcctaaaacc ggtgccgaca
   143101 ccagcatggc ggtttcgatc gcttgacgtc cgatttccgt gaccgtttca atcgtcatgt
   143161 gcagccatcc tattgaaagc tcttcaccat ggagcccacc acgagatacc agccgtcggc
   143221 caggacgaag agaatcagct taaacggaag agaaatcatg acgggtggca gcagcatcat
   143281 gcccatggac atcaggacgc tggccacgac catatcgacg atgagaaagg gaatgtagag
   143341 gaggaagccg atctgaaacg aaatgcgcaa ctcactgagg acaaacgccg gaatgatcac
   143401 atgggtcgga acctgatcta cttgcgccgg tttgggcgaa tgggacaatt ccaggaaaag
   143461 ttccagatcc ttgtcccgca tctgcttcaa catgaagccg cggatcggtt gaataccgcg
   143521 attccaggca tcttcgtagc cgatttgttc cgcaagcagc ggctgcagcg catccttgta
   143581 gaccgcctgc cccaccggag ccatcacaaa catggtgaga aagagggcca aactgatcag
   143641 cacctgattg ggcggcacct gttgcgttcc gagagcctgg cgaaggaagg agagcacgat
   143701 caccatgcgc gtgaacgagg tcaccatgat gaacaaagcg ggcgccagtg acaggacggt
   143761 caacagcgca agaatctgca gcaccacggc ggtctgtttg gtcccgctct ggccgagatc
   143821 aagcgtcagc gatggcccct ctgcgtgaac cgatgacgcg ccggccagaa ccacgagcag
   143881 gacgagaccg acccatccca tgcatcgggg gacggttcct gcgcctccct tttttgcctg
   143941 ctgcagagat gtgaggttat cgtccggcat gtaacgtctc ctcgcggtat tcagacccga
   144001 cagcctgcgc cggggagaga gccatattcg aggaggcttc aagcaacagt cgctttacct
   144061 gctccgggtc ggtgactttt ccaagcgaca ccagatccgt tggcgtggta ccgagaatca
   144121 gaacctcgcc ggcgacggca accagcatga cctgcttgcg cgctcccagc gaactgctgc
   144181 ccagcacttt gatcaatgga gcgccgccga ccggaagaaa gcgctggccg accctggatt
   144241 tcacgatggc caacagtccc agaatcaacg ccaggacaat gcccagcgcc gagaccatgc
   144301 ggaccacact ttcccaaatc tccatggaac gatcgacttt ctgctcgctc gcaccggcgg
   144361 tctcgccgaa tgacgcggcg cctatccgag ttgctgaatg cgctggttgg ggctcaccac
   144421 atccgtcaag cgaatgccga acttctcgtt gaccaccacg acctcgccgc gcgccaccaa
   144481 cttgttattg accagcactt ccatcggctc tccggccagc ttgttcagct cgatgacaga
   144541 cccctgtccg agctgtaaca actcccgaat cagcatgcgc gtcgagccga tctgcaccgt
   144601 tacctgcagc ggaatgtcga gcacgaaatc gatatttttg ttggccggta ccgcaccctg
   144661 gttatcgacc gggggaaatg aggtcgcctg cgggctcatg tccgcgccgc tggaggcatc
   144721 cgcctgcggg gttgtatcgc cattgcccat gcgcaaatct cctttacttc cggcgcgacc
   144781 taactcaaca ctttggtaac gcggcaggca tgattgcctt tgaatacacc gggctgcccg
   144841 tggaatttcg gatcgccctc taccagacac agcatcggat cgcccggatg ttgatcgagc
   144901 atcagcacat cgccaggact aaagttcatc aggtcttcca cgttgatttt ggctgtcccc
   144961 agttgaaccg tcactgccac gtcacactcc tgcagcgaat ccttaaagcg gcttccccaa
   145021 ctgctgtcct gctccacgtt gtcggcaaag aggcccgagt agagcttttc cttgatgggc
   145081 tccagcatgg aatagggata cgcgataaac atttcgcggg tgatgtcgcc gagatgcacc
   145141 tggagcgtga ccaccacgac aatttccgac gtggtgacga ccatggcgaa ttgagggttg
   145201 ctctccgagc gcagatagtt gagcttcacg ggcatgaccg cctgccatgc cttctccagg
   145261 tcgaccaacg cctgctgaac gagtttcttg atcaaccgca actgaatcgt cgtgaattct
   145321 cgcccctccg gcttcacgtg cgtctgcact tttccgccga agaaaaaatc cacgatcagg
   145381 tacaccagca tggcgtccat gatgtagagc ccgttgccgc gcaacggctc catggcaaac
   145441 agattgaagg aggacggcac cgggaccttc tggatgaagt ctccgaactt gatgatctgc
   145501 gtgccgagga cgctgaattc gatcttctcg cgcagcacgc tggtccagga gacagattgc
   145561 tggcgcgtga agcggtcatt gatcatctcc atcgtgggca tgcgcccgcg aatgatccgc
   145621 tcctgactcg tcagactata ggttttgatt cccccgggtt cttcttcttc cttcggcgcc
   145681 gtttcaacct cgccggacat gactccgccc atcaaggcat cgatttcttc ctgggagagt
   145741 atcttgtcca tgatgttgct gacgtcgcgt ggttactgaa tcacgaattc ggtgaagtac
   145801 gtcgacttga ccgatttctt gggcaacagg ccgttgatcc gttcggtgat gtcgtcgcgc
   145861 aacttatgct ttccctgggg agaacgcgcg gtagccgaat ccaagctggt caacaacaca
   145921 agaatcgcat ctcgaatttg cggtgtccgc gctttgattt gttcgacggt gcccgcattg
   145981 tcggcttcca ccttcatggt gactttgagg taccgaattt ccggtgaatc cgcgaggttg
   146041 acgatgaagg gatccagatc ggcgatggcg ctcgcatcag cgacggcccc atgctcgcct
   146101 ccagacttct cttcagcggc gccatgcgca gccgcctttt ctcccccacc ctcggcctgc
   146161 gtcttttcgg cggatgaccc gcccatcatt ttcatcatcg caaaggcgcc gcccaacgcg
   146221 aggatcaaca ctcccccgac gatgatgatg accatcttca tgggaatacc tgccggtgct
   146281 gctggggcct tttcttcagc tgcttctgac atacaaccct cctgcggaca gtgtttgccg
   146341 gtgccggtca gttgtgcaat gcatatgcca cgtgccgcac agagcagccc tcccgcctgt
   146401 cacaacacag gtcgcagatc gcgtgataag acaatgattt ggagttagtc actctcccgc
   146461 gcgaggacac gtcgcctgag cggcatacgt gttgtcacgg tagtgacgcg ggatctctgg
   146521 gggccgacag aatgttgacg agagacagaa gacgaagagc cgcgaggatg agcgcttcaa
   146581 ctaggtagaa attgccgagt tgagccccgg cgacgggatt gcaccgcgcc ggggccctca
   146641 ccgcttaccg cttgagattc acgagttcct gcaacatttc gtcgctggtc gtgatggctc
   146701 gggagttcgc ctgaaaggcg cgctgggtaa tgatcatgtc cacaaactct ttgccgaggt
   146761 ctacattgga ttgctccacg gttcccgaaa gaacccggcc caatccattg attgtcgggg
   146821 cgccggccag cgctgcaccg gactcgaccg tctccagaaa gtggttgtct ccgacgttgg
   146881 ccaatccatc aggattagta aaacggctca agaccacctg cgccagggcg cgggtttgcc
   146941 cgttcgtaaa ctgtgccatg accttgcctt ccttatcgac gctgatgcga tccagcgtgc
   147001 ctgaggaata gccgttttga gtctggcttt gtacgccgga cgctgcaccg aattgcgtga
   147061 gggaggcgag attcaccgag atgctttgtg gcgtcgtggc gccattcgtc agcgcggcgg
   147121 tgatggtttg tgttccgcct gcggtcacag ctccgctggc attaaaggtc atattggttt
   147181 gcgcggtggc cgctccgcca tcgatttggg aatagacccc ccaggcattc gcggcagttt
   147241 tccggaaata caactgcatc tggtgcgaat tgcccagcga gtcataaaat gtcatccctg
   147301 tggagaagtt gtatgaggta gtgtcagtcg tcgcgaaggc cgccgtgggt gccgtggcgt
   147361 tggcattgag gttcccgaga atggttgcag tactggtgga ttgtggcggg accgcactcg
   147421 aggtcaatgt gatccctccg atcgtactcg tgatgtttcc cagcgtatcg gcctgataac
   147481 cttgcagaag cgctccgctt gcatcaacca cctgccccac gctgtcgacc ttgaattgtc
   147541 cggcccgtgt atagaagttc gatccggaag catttcgtac caggtaaaac ccgttgccgt
   147601 cgatggccag atcgaacgta ttccccgtgg tggtcatgga tccctgggaa aaattcgttt
   147661 gcacatcgtt gaggtacacg ccgaggccga tctgatcgct tcccgcgccg cctgccatgc
   147721 tggaagaaat caaatctgaa aaggtcgccc ggcttgattt gaatcccgcc gtgcccacgt
   147781 tggcaatgtt attgccgatg acacccatgg cgttcccgta tgaacttaat ccggtcaccg
   147841 cggtgaacat cgaagtcaga atgcccatga tctctcctcc ttgttgccgt actctgtcgc
   147901 gtgcgctatc tgcattcggc cggcattcac accggcctcg atcaggctac tgccgtcgtg
   147961 ccggtctgtg tggtcttgtt ctgcgccgac tcctggagcg ccacgctttt ctccatcaag
   148021 gacaccattt tcgtcatctg gtccagttgt gagaattgcg cggtctgcgc aataaacgct
   148081 tcattttcca tcggcttcag gggatcctgg tgttggagct gcgtgacgag caatttgaga
   148141 aaatcgtcct tgccgagcgg tttaggtccc tcagtcgtcg gcgtcgacgg atccgctgca
   148201 ggtgtctggg taatcacttt actgatatcc atagttcctc caatcaggca aaaaagctca
   148261 cccgttcgtt cgatccggca ccacgctctc cccttgctcc gcgctcatcc tctcgtgcca
   148321 ccgtctggga tagacctggt gatgatggac ggttctgctg ctgttgctgt tgttgaaaca
   148381 tccaggcgtt gtctccgcgt ccttgttgct ggtcgaccgt gacccgcaac atgcccattt
   148441 cgaggcctga cgtgcgcaac gacgactcca acgattgtcc ctgttgcagc agcccctgac
   148501 ccaactctcc atgttccgtt cggatatgcg catgaaccgt ctgatcgctc atcatgaccc
   148561 gaacccgcaa cggccccata tctagcggat ccagatccag tgtcacgctc tgtgacactg
   148621 gagccatccc tcgaagctca cccacccgtt ccgattcaga agcacggagc actgcggtgg
   148681 tctggccaga ttcgcttcga ccggacgaac tgtcgttgac ggaaggcgtc gattggtgaa
   148741 cgtcattgat cctatccatg aatgccggcc gggcattctg ctcgactgac ggcacctggt
   148801 tgggaaggga ccgatcagtt ccgccggatg aatcggaaag attctgtccg tccggctcca
   148861 gaaatcggcc tgtgctggat cccgcttgcc cctcgctcag tgacgcacct tgcgccagtg
   148921 catcaagaat cgccgaacgg tccgcgccct cactcgggcc ttgttccgcc atgtgcgggt
   148981 tttgcttcga cgaggtcatg gcagcaatgg cgggattcat gcgatccgca tctgtccgag
   149041 ccgctgcagt cgagtctgtg cggtcttcca ctctggcgtc cggcgaagaa ttgtcgccgg
   149101 cgagggatgg cagctctttc gctgttgtct gcaccatctc gttcccgttc tctgcccgtt
   149161 ccttagcctg ggccgcgtcc ttgcctgcgt ctgctttagg atccgactga cccgcaagaa
   149221 cctcttgcgt accagcacca gcttcagatg tcgccgcgac cagagtcgtg actgaggcag
   149281 acccatcttc ggcgcgatcg cttgaaatgg ctgcagccgc gttgacggac gtctcagagt
   149341 ggctgtccga ctgagcctca gcttgaggtg tctgctgttc aggtggagcg gcctgagcag
   149401 tgggcaccat catggaggcg agcaacatgt cctgcgacac ggcgtcttgc ccgggatctt
   149461 tctttttgga ttccttggtg gtgctctttt cttctgattt gtctgtggac ggctgtgcct
   149521 tctccccggc acattcacac cggttcgacg agtgatcatc ggacggtgct acgcttgatc
   149581 gctccgatgg ttggctggag gagtcggaga tagagcgact gacttggcgc gcgtggagac
   149641 ctgccttctc cccgctgcga ggcgtaggag cctcgtgttt gggtggcgtc tgtcgcgcct
   149701 ctgcccgccc gagcaccgac tcgaagttcc gtgatggatc cgaaccgtga accgccggct
   149761 gacgatccct ggcatcctga atcccctgtg acgagcggct tggaaatccg ttgaagactg
   149821 gttgcatatc agtggccata caattcctgt ctgtgacgag accgtgaata gacagtggag
   149881 actattacaa aggccatgcc atgagactgc cgcaggaaaa tggcctctga cgcgaggttt
   149941 tgtgatccga gagggaatcg agaatggaga gaaggaaatt tctgcagttg aagatcggca
   150001 aaagctgccg tgagaacgag acgtgaaacg aatgactagg gtgtggtcag caattgttcg
   150061 gtcaaccggg ctgctcgctc cggcttgacc tccgcgagaa tggcgcccgc ggatttgcct
   150121 ttgagcagcc gaagcacttc cagcgcttta cgttcaggca tacgttccag tctggctgcg
   150181 gcttcttcgg ccggcatggc ttcatagatc ttcgcaagtt gggcctgatt cacgttgaca
   150241 gccggagtgg ctttggccgt cgtcttagcc ttttcggctt cgcccgcgcc tttggcctga
   150301 gcagcctggc ggcgcttctt ctccgcctcc accgcttgct catggcgggt cacgatttgt
   150361 tccaactccg ccttgagctc cagaagatgc gtctcggatc cacgcacggc cgtttcgcgt
   150421 ttgtctaaga gccgtttccg ttgttccaac atttcataga tttcacgtgg ggcgctggtc
   150481 gccgggcctt gcacatcttt tttcacgctc tcaggcttgg tctcttcttt ctgcggcaca
   150541 gcagccggtt tcacttcttc tgtcgcatgg gcggtcgtga tgagcgtgag gaacaccgca
   150601 ccaaatgcta tcagcgccac cacgccaaca cacctgccct gctcagagcg gctccccgtc
   150661 tccatcatgc ccgttctccc ttatgcaatg ggcttcgtct ccaggcacgt tcatcgagta
   150721 attgctgatc ctggcgctca cgacggcgtc gtatctccag cgcggctcgc gcatcgagga
   150781 gatcgagctt tttgcgatac tgcatcgctt cgagaagttc tgcgcgcttc tgttccatcc
   150841 tcgcttgctc ggtcgccaat gcctgttcca accctttccg tgctgcgatg gcctgatcca
   150901 tggcgtcgag atggccgtag acctgatcca cggtgctgcc tgcacgaacc tgatgcagat
   150961 accggtcggc atcttctttg gctcgggatt ccaacatggc cattcgattc accgtttgtt
   151021 gcagggcatg actgagttcc gccaattcca gtttggcgac ttcctccagt tgcaccgcat
   151081 aggctcggag cacagtcacg ttcattgaat cgtccctgcc agtgccagaa gtgcgtcgat
   151141 ggattgcggc aacccgaccg cttgtttggt ctcctgccgc agaaacgccg taatgccgtc
   151201 gtgggccgag acggccttat cgagatcttt gcttgtaccg ggcttgtatg cgccaagggt
   151261 aatcagatct tccgagcgac gatacagtgc cgtacgttcg agtaccaggc gcgcggccgc
   151321 ataatgggcg ggcgtcacga tatcccgcat cacccggctg gtgctctgca gaatatcaat
   151381 tgccggaaaa tgattacgcg cggcgagttc acgcgacagc acgatatgtc cgtcaagaat
   151441 cgagcgcacg gcgtccgcga ccggatcatt gagatcgtcg ccgtcgacca gcacggtgta
   151501 gagcccggta atgctccccc cgctttgtgc cggcccgacc cgctccagta gcttcggcag
   151561 gacggcaaat acagaggggg tatagccctt ggtcgtcggc ggctcaccaa tggccaggcc
   151621 gacttctcgc tggctgtagg ccaatcgtga aagcgagtcc atcatgagca ggacatgttt
   151681 gccgcagtcg cggaaatatt ccgcaatggc agtggcgacc agggctccac gaatgcggac
   151741 gagtggtggt tggtcggatg tcgccacgac gacgatggac cgagcccgtg cttcaggcgt
   151801 gagatcgcgt tccaggaatt ctttgacttc ccgcccccgc tccccgacca gggcaatcac
   151861 ccgcacatcc gcctgcgtat agcggctgat catgcccagg agcacgcttt tccccacgcc
   151921 ggatccggcg aacacaccga tcttctgacc ttgcccgcat gtcagcaagg cattgatggc
   151981 ccgaataccc agatcgaccg gttgcgtgat tctggcccga tgcaaaggat tcaatggcgg
   152041 cgcatacagc ggcacacgca catcgctgcg aagagccggc aagccatcca agggatggcc
   152101 gaggccgtca aaaatacgtc ctaacatctg tggcccgacg gggacggagg cgacatgtcc
   152161 cttcatcacc actcggctgc ccggcccgat cccctgcatt tcacccaatg gcatcagcaa
   152221 cacgcgatct tcgcggaacc cgacgacttc cgccatcacg gacccgtggc ccccctcacg
   152281 tgtgatctca cagacttctc ccacggaggt gaacggtcct gaggcttcaa tgacaatgcc
   152341 cacagcctga gcgaccctgc ccgtgaccga taagggttcg acatgttcga ggcgtgcgct
   152401 aagcttcacc ggcatcccgc tttcttaagg cttcgccgag tcgcaataat tgggtgtcca
   152461 gtgtcgcatc gatcagcagg ctctgcgcct ggacgaggca ccctcctgga ctgatggaag
   152521 ggtcggtctc aaattttaat gtcaacagtc catggggtgt ctgactcaat gccgttcgtg
   152581 ccgattcgag cacggtgaga tcggacggat gcacccgtac acgtacgagc ccgctttcat
   152641 gcaggtgtgc gagagcggtg cggacttgcg tcacgatcag gtcgcgcttt tccgtcacga
   152701 catcccgcac caccttgtgg gcgatcataa acgagaggga cgcgatttct tcttcgaccg
   152761 tctcgtgcag gctttgccag gtttcttcca agcgtgtcat cagggatgcc acgaggctct
   152821 gctcacgctg ccgcgccgca gccacccgct cggtcgaacg cttttcccct tccgcaacac
   152881 cccgttcaaa ctcggtaaga tcttcagttc caaacggccg attgccgcgg ctgaaatccg
   152941 caagcggcac gggacggagt tgaatattgc cggagcgaat caacgtgcgg gtgagcacgg
   153001 tattttcctg tcgcaaccgg tagagttcca gcaatctgga caccgccagc cggaccagct
   153061 cgacttggaa cggtttggta agaaaatccg ccgctccgga tttcatggct ctcacggcca
   153121 gttcgatgtt gccgtggcct gtcatcacga tcccgagcaa gcgattatcg atgtcgagcg
   153181 cctgctgcag aaaggcgatg ccatcggcgc cgccaagctg cacgtccaca atcacgacag
   153241 caacggagcg ggttcgcaga tgactcaacg cttccggaac ggagccggcg gtgagaacgg
   153301 gatgccccgt ggactcgagc atctcggcca gcagcaagca gatggagggc tcgtcatcga
   153361 cgatcaggac ggcccgcggc gacagttcct tttctgactc gggcgaagcc gccatcgaaa
   153421 cgcccgtgcc cgcggcagcg ctccccattt acaataactc ctcgcctccg ccgcctccga
   153481 tgacgatgcg gccttcctcc tcgagtttgc ggcagacttt gagaatattc tgctgggact
   153541 tttcgacgtc cgacaccttg accggcccgc gtgtctccat atcctctttc agcatttctg
   153601 ccgcacggct cgacatgttc ttcaggaact tgtctttgat ttcaggcgtc gcgccccgca
   153661 acgcgatggg caggtcttcc ttgctgattt ctttcatgag ctcttgcatg cctcgagaat
   153721 ccagatcgac caggtcatcg aagacaaaca tcaacgcacg gatgctttcc gccagggcct
   153781 gatcacgttc ggtgatcttg gccatgatgg cgccttcggt gttcttatcg acgcgggtca
   153841 ggatgtcagc catcagctcc gcgcctccga cggacatgct cgacatcccc atcgacgccg
   153901 acaggatttc ctgcaaactg tcgctgagct cggccagcac ttcaggctgc acttcctgca
   153961 tggtggccag ccgaagagag acgtcggcat gcagatgcac aggcaacaga gccagaaccg
   154021 cgctcgcctg ctccgcctcc atttgcccca ggcagacagc aatggtctgc ggatgttcga
   154081 tcttgagaat ctgcgcgacc gtgcgagcgt cgacccattt caatgcgtcg atccccggat
   154141 aggttttggt gttcagggat tccatcatcc gcgcagcctt ttccgggccc agcgcctttt
   154201 tcaggatggc ttccatgaat tcccgtcctt cgaattgcac ctcgcctgaa gagctcgcct
   154261 gctcaaattc cgcgatcacg ctgtcttctt cctgcttcgt gatattcgcg gtttctttca
   154321 tgaactcgcc gagcttccga atatctttcg gatcgagcga cttcatgacc gccgcggcgg
   154381 cctcctcccc gatcgctcga agtaaaatgg cagctttttg cgcgccgctg agctctttgt
   154441 tgatggccat acgcgttacg cgttactctt cagccactgc ttgaccacga cggcggtgtt
   154501 cgcagggttg tttttcgcca tgtcgaggat ctggccaggc tgcttgccgc tgatggcggc
   154561 ctcaacctgt ccgaccgatg cgggcagtgc cggcgtctcg ccgactgcct cgaccggagc
   154621 ggactgtacg agcatgacca ttaacggccg aacgaccatg aagagaatca ggaagaacag
   154681 cagtccgccc acggcatacc ggatatacgg catccacgcc ctggtgctgt cagccgcagc
   154741 ttcgacacca gcgccgaccg gttcttccac tccaagcccg aactggatac tcaccacctc
   154801 cacctgatct tgacgttcgg tggaatagcc catggccttc ttgacgattt cttcgatgcg
   154861 cttcatttct tcttccgaac gaggcacata cttcttcggc tgctcggcag caccctccgc
   154921 tgctttgcca ccgccctcat acgtcccgtc aaccagcacc gcgaccgaga gctttttgat
   154981 cgtgccggtc ggctcgacga tgcgggatac ggtccggctg atctcgtagt tcaccgtctc
   155041 attcttcgtc tggttattgt tcgagctggt ttgtcccccc tcgccttctg ccccaccggg
   155101 cacattcgat tccacgccgg gtacaccgcc ggtggtccca ttgacgccgc tcgacttttc
   155161 ctgtccgcgc tgttcgctgc gtacgacttg gccgttcggg tcatagcgtt cttccgtggt
   155221 ctcgattttc cggaaatcga ggacactcga cacccggacg acggccttat tcactccaac
   155281 aatgcgttcc agcatggttt gaatgcgcgt ctcgatgtct ttctccaagg tgcgctggta
   155341 ttccatttga gtgccggaca gaccggccga ttcatcgcta ctggaattgg agaggagatt
   155401 tccgtgacca tcgaccacgg tcacgtcgcg agcctgcaat ccttccacac tgctggagac
   155461 gagatgcacg atgccctgaa tctgagcttt cgataagttc tggttgggcc ggagagatac
   155521 gacgaccgat gcgcgtgcgc gatcctgttc agttgcaaac agccgccgct caggaatggc
   155581 taagtgaaca cgagcccgtt cgacttccgg catctgcgtg atcgtacgcg ccaattctcc
   155641 ttgaagcgct cgccggtagt tcagcttctg cacaaaatcc gacatgccca tagtggtgcg
   155701 atcaaaaatt tcgtaaccca caccgccgcc atgcgggagc ccctgcccgg ccatttccag
   155761 ccgtagatcg tgcacctgcg cattgggcac gaggatggtg gtgccgccgt tggtggtctc
   155821 atagggcact ttggcgtctt ttaatttgtc gatgataccc gcggcatcgt cggtcgccag
   155881 attggcaaac agaacctgca tgtccggttg ctgtgtccag agcgtcacgg ccaccagccc
   155941 cgcgatggat ccggccaggg cgagcagaat gatgaaccgt tggttgatcg tgaactggct
   156001 gaattttgaa aacatgtgct gtgaaatcct ttatgcgtga tatccgcgcg ggagtccgat
   156061 cgctaaatct gcatccgttg gatttcctcg taggccgtca cgagtttgtt tcgcacctgc
   156121 atcatgagct ggaaggaggc atcagcctgt tgcaacgcca ccatggtttg atgaatgttg
   156181 gtattttggc cggtcaccaa cgactcaacg gcctgactgg cccctgcttg cgcatcgttg
   156241 atatgcccga tcgcttcttt gagcgaaccc aaaaaattgg cccctcctgc ctcgccggtt
   156301 tgcccagctt gctggagccc gggcgcttcg atcggcttga tgagattggc acccgcgatg
   156361 tgcagatcgg acatgattac ctcccgattt ccagggcgcg attccacatg gtacgggtcg
   156421 cattgacggc ttgtacgtta gcctcatagg ctcgagacgc gccgatcata ttgaccattt
   156481 cttccatgac gttcacgttc ggcatcgtga cgaacccctt cttgtcggca tcaggatgac
   156541 gcgggtcata caccgtttgc cccggtttct gatcttcgat gacccgggcg actttcactc
   156601 catccaaggc atgtcggccc gatcctttgg acacttgcgt gaacgccttc tgaaaggccg
   156661 aggacacggg ggctgcctga aacacgacat cacgccgacg atacgggcca ccggtactgg
   156721 ttttggtgga ttgcgcattg gccaggttgc tggcaatcac attcaaccgg tgtcgttgtg
   156781 catcgagcgc cgatacggag acagcgagac tatctgataa atccatcaca cacctcgtta
   156841 tggttcgccc atgactcgaa caagcgcatc actgtatccc cgaaagatta ccgtccttcg
   156901 cgaatcgcac taaggagcgt tttgaatctc atgctgatga tggaagcgga cgtgttgtac
   156961 tgctgggcgt tgtccgacat cttggccatt tccagttcga tgttgacgga attggcatcg
   157021 agaggcagat cgccggcagg aacctcttca atgcgtccct gtactcgttg aaacccgctg
   157081 cccttcggcc cgatgtgctg ctgatgggtt gagaccaagg cgatcggcag tttgccctgt
   157141 tgcgcattcg ccagagcctg accgaagttc aggtccgtgg cgcgatactt cggggtttcc
   157201 tcattggcaa tgttggctgc aatcacctgc tggcgggccc cgcgcagatc caatgaacgt
   157261 tcaagcagct gcatggtccg gtcaaaaatg gtcatggtcc acactccgta gaaagttcgg
   157321 tgttcaacgg tgcaatctgt gtaccccgtt cagaatgggg atttttccgg gttcacccga
   157381 gtctgtgtga caatgtgcgc tcggccggca ccgggcaaat acgacctaga gggaaaattt
   157441 tgcccagcat cgggcgaatg agacgtcagg gtttttctgc ctccacctga tatcccagat
   157501 cacgatattc ccgtaactta ttgcgcaacg tgcggatact gatgcccaac tccttggcgg
   157561 catgcgtccg attctctttg actcgcgcca aggtcttgaa gatcagatcc cgttccattt
   157621 cccacagcga cccgtgcgct gagggcgcga cgagcgtttc tacggtttcg actggttgga
   157681 tgggaaccgt tccgtccccc ggcatcaagt gatcgacgtc aaccgcgttc cccgttgtca
   157741 ctaaaatggc gcgttccatg acattttcca gctcgcgcac gttccccttc catgcccgct
   157801 gctgaagatc tgcgatggcg cgctcggaca gggtcggcac ggtaaggcca ttgcgttggg
   157861 ccgaggaacg gagaaaatgt ctggcgagca gcggaatgtc gcccggtcgt tcacggagcg
   157921 gaggcaccgt gacgggaaat acattcaaac ggtaaaacag gtcctctcgg aaacgccctt
   157981 gcgtcacctc gtggtagaga gagcgattcg tcgtcgcgat cacacggatg ttgaccggga
   158041 ccggatctcg ccctccgatg cgatcaactt ccctctcctg caacactcgc aagagtttcg
   158101 attgcaggcc taaattcatt tcgctgattt catcgagaaa cagcgtgccg gtatgggcca
   158161 tttcaaactt gcccagcttt ttctgaatcg ccccggtaaa cgccccgcgc tcatgcccga
   158221 acaactcact ctccagcaaa ctgtccggaa gcgccgcgca gttgagggcc acgaaaggtc
   158281 gatgggcacg ggggcttctc gcatgaatgt accgggccag taactctttt cccgtgccgc
   158341 tttcgccgct gatcaacacg gtggcttggc tggcggcgac cccttccagc gtcgtgagca
   158401 gacgaatcat gccgggatct tgcgtgagta tcgcgcgtgc ctccagcgcc gcaggggcat
   158461 cctgctcatc aggctctgcg ctggcttgaa gattgagaat cacccgctcg agcaggtcgg
   158521 tcgagaacgg ttttaaaata taatcattcg cgccatattt catggcttcg acagccgtct
   158581 cgacggtgcc gtacgcggtc ataagaatga tgaacgtctg cggagctttc tgttttaggg
   158641 ctttgacgag ctcgagcccg ttcagacggg gcatttttaa gtcggtcacc accaaccagg
   158701 gcttcaaccg ttccacctgc tcgatcgcat ccgccccgtc gatggcgcta cggacttgat
   158761 accccattcg acgcacggtt tctgacaatg ccgttcgcat cgacggttca tcatccacga
   158821 tcaagaccat gcgagcctca tcggcagaag cggaaggccc ttgtaaggct ggttgcgcgc
   158881 tcattcgtac ctcttttctt cggtgatgct cgtaatgtga cgtgaacgtt ctgaaggggc
   158941 agacacggtg acaagtgaaa caggcgtcga cgaaggttgt cgtggtcctc gcgggagggt
   159001 gatcacaaac gaggtgccat ggcccgggcg actttccaca tcaatccgcc cgtggtgggc
   159061 ttcgaccagg gcgtgcacga tggcgaggcc caacccggtc ccctgatcct tcgtggtaaa
   159121 gaacggatca aatactctcg actgcagttc agccggaatt cccgtaccgg tgtcgcttac
   159181 cgtgatatga accgccggta cctcctggat ctccggaggg gatggacagg ccgtgagcgt
   159241 gagcgtcccg cccttcggca tggcctgaac cgcattcaag actaaattta agaggacctg
   159301 tttcatcttg gggccgtcgc accagagctg gggtacaagc ggatgcatct ggcagcggac
   159361 gtcgacggtg tccggcggga tggcgtgact ggccagtgtc agcacttcac gtatcagtac
   159421 ttccgtgtca tgccatccca ggcgcgagca gtcgggacgg gtatacacga gcaggttcga
   159481 gaggagctga tccatggatt gaaccgccat ggaaatatgt tccgcataac tccggagttg
   159541 aggctggtcc cgaaggtcct tgcgtaacat ggaggcaaat aactcgacac tgcctaacgg
   159601 gtttcgaatt tcgtgggcga tgctgccgac catctggccc atggcctcca accggttgcg
   159661 ccgttgcaac cgatcctcaa gctggcgaat gcgcgtcacg tcatggatca acaccagttt
   159721 tccgataggg ttcccggatt cgtcggtgag gtcggtttgt gagagggcga tggtgacgcc
   159781 gctggggagc acgagcgggt actctccatg gtctttgcgg atttctgcca acagggcgct
   159841 tgcctggcgc cctcgcagtt gagcctgtgg tacgcccagc agctgctctg tggaatgatt
   159901 gcaccgcacc accacatcct gtgagtcggc cacgatgacg ccggtgtcca gggattccaa
   159961 cacggccgtg acatgggcac gcatttcctc ggtttcgcga agatgctcgc ggagactggc
   160021 attggtttgc gcgagctcga gatccatttg ctggagccgc gtcgtcaacg catcgtacga
   160081 ctgctgcagg acggtggcgg cctgatcaaa atcgcgaaac gcgcgcgtca gcaaatcgtt
   160141 gttggtggtg tcgccttcct gcctgatcac ggttttttcc cccgtttatc gaccggtggt
   160201 tccggcaatt cattgtccaa catggctgcc atgcggcgaa cgagactatc aggattgacg
   160261 ctcagtgcac gcagaccgtt tttcgcgaaa tcctcgcgct tctcaccgcg tgccagttga
   160321 accatctgta gttgggccca cgcctcctgc tccagctcaa ggccagcgac gacagcctct
   160381 ttgtacatgg ccagtgcctg cgaccggcga ttcagacgag ccagcacctc ggcatgccgc
   160441 agcaggtctg ccgcgggaag ttcctgaccg gctttgatca ggccgtcata aatagccgcc
   160501 gcctcggcgg gttgtttgga ctgcgccaac gcggccgcga gtttgagctg caccatcgtg
   160561 cggtcatggt gccgcggatt gtgagccaac cattgtttac ccagcttgag cagggcggcg
   160621 agatttcctt ccccctcgaa cgagttcaga attccacgca aggcctcccc ggaaaaccgg
   160681 ccggttggaa attccaggcg gtaccgttca aacaccgagc gggcggcccg catatctttt
   160741 tgttccatgt agctgtaagc cagccccatg agcgccgctt catggaactt ctctgccttt
   160801 gcatcgcgaa ccagtgactg gaacagccgc gcggactcca cgggaaatcc taagcgacga
   160861 tgtgcctctg caatcttgag caacagctct gtgccggcat acaaccggtc ggcaaacggc
   160921 ccgtgccgat ggaagatgtt gatcagttca aaatcgtctt ctgccttaag cgcagcttca
   160981 agacgagggc gaaggaaacg gaccagctgc acgccgcctt tttccggcca gggatcgttg
   161041 tcgaattttc cactgcgtaa caccacctgt tcatacgcac ggacggcacc ttctggcttg
   161101 cctgccctct ccaaggtttc tccgaggtgg aatagcgcct cgctgccgac aattgatcct
   161161 tcattgtcct tggcactctg ctcgaataat cggcgaggac tgagcatctc ccctgccttc
   161221 aagggaacat ggtccagatg cgccgaaatg gtatgtcgaa gattgatctc ttctccctcc
   161281 ggatccagat gttcctgcac atcggcatat cgaaggcggg ccgtcgcggc cactggagcc
   161341 tcggggtatt ggcttaataa cgctgcgtag aaaatgctcg actcagccca ccgcccggct
   161401 tctttgtaac tatcggccag gtaagtcagc acaaacggag tttcaggccg gtttggatat
   161461 agattgtaga aatgcagcaa ctgctcccgc atgaccggac cgcgcttggc ctcccctgcc
   161521 gtatcagcat accgcagcaa cgcaaaggca tcgctccgca gcgcggccgg ccatcggccg
   161581 gaaatactct cgtagagcgc gtcggcatct ttcatccggc ccagccgata gagactgtgg
   161641 gcttcgccca aggaggcaga gaccagcagc gtgggatcca cggtccgctt caatacgtga
   161701 tcgaaggttt gggtgctctc tttccaattt ttaaaacctc gctggacata ggcgagaccg
   161761 agcatggccc ggttggcatc aaacgagtcg atttccgaca gggaaagcgc atgctgatag
   161821 gcaatctgcg cttcctggaa ccacccttcg atgcgataga catcgccgat gcgccaggcg
   161881 gcccgcttgg cattcgtcga ttgcgggttc tcgcgcatga gtgttttgta ctgatcgatg
   161941 atgtccagtg ggcggacacc agggtcgtga ctctgaagcg tactttccgc gaggaacgcc
   162001 tggatggacg atctgagcgg cgactcccgg cggtcacgaa gcatgttcgt gaaatggagg
   162061 cgtgcctcga gatattgccc ttgatggtag agaccgactc cctgttcgaa ctgcttccat
   162121 tccggaattt ccggcagccg ctcgaaacgt ggacctggat caggtaatgc tccacgaacg
   162181 agctccgatg gctccgccat catggctggc agctcttgtc gcatcgtgga aaggccaccc
   162241 gtggccgtgg cggggacgat tcctactagt agaagccaac ttacaatagg agtgaggacg
   162301 tagcgggctg tggtggatga atttcgcaca ggcggcaatt cagcaagtcc tgtgccccta
   162361 gaggagtccg gtaacacact gcatcgcttg atgatttagg cgaaccgagg cggaaaactg
   162421 agagaggtgt cagaaatacc aacggcggga acgaggaagc ggtcaaaaaa atgacatggc
   162481 aagagaggtc gtaagatttg tcagttttgg atcgagtagc cgtgactttt cggatcaaag
   162541 cctttccgtt tcagtttttc caccagtgtt gtccgattga cctgcagcaa ctgcgcggcc
   162601 cgactggtta tgccatttgc cttgcgtagc gcttccccaa tgagacggtt ttcgtaatgt
   162661 tcgagttctt tggtcagatt gataccatct tcggagaagc ggataaattg ctcgggggcc
   162721 tcgaccgcct ttccgcctgc cgttttcaac gcacgttcag gaagatcggc cagcgtaatc
   162781 attcccctct tcttcaacac gcagagacgt tcgatcatgt tctcaagttc acggatattt
   162841 cccggccatt cctcttcggt catgcgaacc agggcatccg gctccatgcc aagaatctcg
   162901 gtcctgcgta gttgattgaa ttgagcgata aagtggttca cgaggagcgg aatatcgctg
   162961 cgccgttccc gtaatggagg aatgtgaatg ggaatgacgt gcaatcggta atacaagtcc
   163021 tgccggaatc gtcgctcctg tacggcttgc gccaaatcct gattggtggc ggcaataatc
   163081 cgcacatcca cgtttatagt cctcgttccg ccaactcgtt cgaagcatcg ttcctgtaat
   163141 acccgtaaca gtttcacctg caacggcagg ctcatttcac cgacttcatc taaaaagatg
   163201 gtgccgccat gggccaattc aaaacggccc agccgcgtgt gcgccgctcc ggtaaaggct
   163261 cccttttcat ggccgaacag ctccgattcc agtagcgttt caggaatcgc cccgcaatta
   163321 acgggcacca gtggacggtc tcggcgcatg ctattgaaat gcagcattcg cgcgatcaat
   163381 tcctttcccg ttccgctctc cccctcgatc agtacggtgc tatcgctatc ggcaaccttc
   163441 tcgacaaaat ccagcaccat ccgcatgggc gcgctggtac ccactaaatg ttcaagacga
   163501 tactggtctc gtaccgcttt tcgtagcaga tgattttcct gtttaagttt gtagacgtcc
   163561 aatgcttttc gcaccacgac cgcaacggtg tcaggctcaa acggtttggt gataaagtcg
   163621 aacgcgccgg ccttcatcgc ccgcacggca taatcaaccg tgccatagcc ggtcatcacg
   163681 atcgcaatca ctttggagtc gatttttgag attcggtcta tggtttccag tccgtcaatc
   163741 cccggcatct gaagatccgt cagtacgacg tgtaccggct gatccttcac cgcctccact
   163801 ccatccagtc cgctcgacat gaccgtgacc tgatggcctt cgctcgtaag tgtttccgcc
   163861 agtagttggc ggactgcggg atcatcatcg atcacgagaa tgtgtgactg gctcataagg
   163921 gagcactcct ctctggaaga ccgcaatctc ggagatggct ggatgcaaga tgactctgga
   163981 caggaagaaa ctgagcgatt cgcatggtag acatatgttg gttcagctta ttgggaattc
   164041 agactttatt caagtaaaag taaggccttg cgggaaaatt gcgctcgtct gctttacacg
   164101 atagtcgacg gactcaagat gcccaaacgc aacttgacag ccaggaagaa caattgtagg
   164161 gttccgctct gcgggacttc cacgattctc tcgacagtta ctcgtgcggg ctggcgtagc
   164221 tcaattggca gagcagcggt tttgtaaacc gccggttggg ggttcgattc ctctcgccag
   164281 ctccacaaat accta
//
LOCUS       DAOQPD010000002       132302 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_35_length_132302_cov_21.768471, whole genome shotgun sequence.
ACCESSION   DAOQPD010000002 DAOQPD010000000
VERSION     DAOQPD010000002.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 132302)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 132302)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..132302
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_35_length_132302_cov_21.768471"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            40..1335
                     /locus_tag="PK063_00755"
     CDS             40..1335
                     /locus_tag="PK063_00755"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HMZ95589.1"
                     /translation="MQTTAFTSFDSLGLSPTLLRNLTKAGFSEPTAIQAQAIPHALSG
                     RDVLGCAQTGTGKTAAFVIPMLERLTGTPKGQPRALILAPTRELAIQIQATIDTLGRD
                     LQLFATTVVGGADMQAQVRGLRQRPDIIVATPGRLLDHMWNGTISLLAMNILVLDEAD
                     RMLDMGFAQQINQILDAMPEERQTLLFSATMPMDLARLAQASVKDPVRVMVAKSATTA
                     EGVAQAVHHTTHDRKNALLMSLLQSESDTVLVFARTKHRADRLGNLLDTAGHRVAVLH
                     GGRTLPQRRAALEGFRRGTYRVLVATDIAARGIDVANIAHVINYDVPNCPEDYVHRVG
                     RTARMRTTGRATTFVTAEDQEQLRAIERLLGQAVPRAEGSPASLPPSSRPDGHAPRNE
                     PERRRRRGGSAQGWRQTTDGGSREANGGIKNGSDLGPVS"
     gene            1371..1712
                     /locus_tag="PK063_00760"
     CDS             1371..1712
                     /locus_tag="PK063_00760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95590.1"
                     /translation="MSDQNQDAPRAATQWVRIPDGTMVQHRLDGQKGHIDGLTEIVTG
                     PSRNPDGRTQYRINVGKGDRVLIAEEDLLILTDAEGMVRMAKEKGEYRSLVSKQLRGI
                     FGEDRFIVKTS"
     gene            complement(1992..2273)
                     /locus_tag="PK063_00765"
     CDS             complement(1992..2273)
                     /locus_tag="PK063_00765"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95591.1"
                     /translation="MKITSVWRGNKPNHKKKRTVPKLRIRWTELGLVDPSVEPHETPM
                     DQIRREVTALASSGFGAETRARSEQTQTRPARTLARTSTTRTARRPAGS"
     gene            complement(2634..4187)
                     /locus_tag="PK063_00770"
     CDS             complement(2634..4187)
                     /locus_tag="PK063_00770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HMZ95592.1"
                     /translation="MQRATLNFETLLEVTNALNSQRDIESLWRVIADQIQKVIPWDRA
                     GITLYESNTDAFRFYAVITNMASPALAHDSVIPREGSAVGWVYDHRRLHIRGNLQKEQ
                     VFLEDRFYAQEGLGRMINLPLLVREHCLGTLNIGSVHGGEPDPDDCKFLQQVATQIAY
                     AIDHVLAYQQIKQLSERLRRENEYLAEEVKASRNQRLLVGASSSFSKVVELVKAVAPT
                     DTTVLLLGETGTGKEVLAQALHDLSARSQKPFIRVNCAALPSGLIESELFGHERGAFT
                     GAQLRRAGRFELAHTGTLFLDEIGEMPLETQAKLLRVLQDGMVDRIGGTQPVSVNVRL
                     IAATNADLSAAIQQGTFRADLYYRLHIFPIAVPPLRERREDIQLLAQHFLTQIGAKHK
                     RPHLTFDPQSMARLLSYNWPGNVRELQNVIERAVILSSSSQVTVDEMLLPIVRAGRAV
                     LTHQPESLEDLERHHIIMILERTKWRIYGDQGAANLLGLNPETLRSRLRKLGIRRPVS
                     RSSETSPMA"
     gene            complement(4194..5879)
                     /locus_tag="PK063_00775"
     CDS             complement(4194..5879)
                     /locus_tag="PK063_00775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate export family protein"
                     /protein_id="HMZ95593.1"
                     /translation="MWKFLLLWFAFTLPSGAILAPTSLMAEAGHVGYGPTSPALFSSA
                     ESLVIDTDPVALLPPPAAFDIRNFWMRADLRVRPEWRSGVCFGGGPPMNGACNSLNLS
                     GSGTSAHDGSKASDFFIQQWARLGLGYDPSPTLNFYVELQDSATWGGSGNPTDGGQSA
                     DAANHQCGTQRPGQCRLGIRAGYALIRNLAGVEGLSAKFGRQYVVFGNQRLFGHFDWA
                     NTGYSHDGVMLSYARTDFDLKLGWFRHSETDLGQGHPGGSLTPNLLTCNQDVTSQSVC
                     NPAVAQHAADAGSDVDMVVFYNQIRGVPRMIVEPYYVLYYNRLPERANPGQYLPKSAS
                     QLRHMVGLRLELRDGNWDLVHETAYQFGRTADGFGFDNQRNLSINAWASGTWLGHTWY
                     AHPWKPRVAIGFDYASGDGDSNCVTPGGTLARSCGGNANTFENFFPTNFLHVGYMLNG
                     AWRNTVQPQVNLQARPTTRDHVEVWAMRKYLASARDNWYRGSQGPLIFSRSDNQTTHV
                     GDELDVAWSHMFADGTVSVAVIYGHFFSGPYIRHQLGTSMDQDWGIVQLWTNF"
     gene            complement(6012..6503)
                     /locus_tag="PK063_00780"
     CDS             complement(6012..6503)
                     /locus_tag="PK063_00780"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95594.1"
                     /translation="MKNTIALYSTAFLIGAWPLLDLSQAQAFSNNPEPVVWNSNQKSA
                     AWAEELLGQVVTYQTMAEKNLIPGSFQPYVEQTSKIRELHRSGNRRATYDGVNALMVM
                     LEARVGGIDEHSAEALWDFCYRVTPDEFHARDRHIRAKGADTVKEHEEFMRNMEERAG
                     MSF"
     gene            complement(6787..8730)
                     /gene="glgB"
                     /locus_tag="PK063_00785"
     CDS             complement(6787..8730)
                     /gene="glgB"
                     /locus_tag="PK063_00785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HMZ95595.1"
                     /translation="MSPQNLAQNPGPSATTRLTDDDVYLFNEGTQFQLYDKLGAHPMV
                     SHGEAGTYFAVWAPNAEQVSVIGSFNDWNRDAHILHPRGDSGLWEGFITECAKGALYK
                     YHVHSRHADYRVDKSDPLSFFNEIPPKSASIVWDLDYTWTDDDWLRTRGRANALNAPM
                     AIYEMHVGSWKRIAAEQNRSLSYRELAVPLAEYLQKTGFTHVEFMPLTDHPFFGSWGY
                     QTTGYFAPTGNYGTPQDLMYLIDTLHDHGIGVLLDWVPSHFPTDEQGLGFFDGTHLYE
                     HADPRQGFQLDWNTFIFNFGRNEVRSFLISSALFWLDKYHFDGLRLDAVASMLYLDYS
                     RKEGEWIPNRYGGRENLEAIAFLKRLNEEVYRHFPDVQTIAEESTAWPLVSRPTYLGG
                     LGFGLKWDMGWMHDTLTYMQKDPIDRKYHHHNLTFRMLYAFHENFVLPLSHDEVVYGK
                     GSLLGKMPGDEWQKFSNLRLLFGHMYSQAAKKLVFMGGEFGQPAEWSHDGQLEWSALE
                     LPLHQGVHRWVTDLNHTYRRESSLHEGDVDPSGIEWIDCRDAESSVISLIRKGRATDE
                     IILVVCNFTPVPRPNYRLGAPRGGYWKELLNSDAAIYGGHGWGNAGGIEATPVPLHGR
                     THSITCTLPALSVLFLKHSSSPL"
     gene            complement(8727..>10021)
                     /locus_tag="PK063_00790"
     CDS             complement(8727..>10021)
                     /locus_tag="PK063_00790"
                     /inference="COORDINATES: protein motif:HMM:TIGR02457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016866 - intramolecular transferase
                     activity [Evidence IEA];
                     GO_process: GO:0000023 - maltose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="putative maltokinase"
                     /protein_id="HMZ95596.1"
                     /translation="SIGTLVGSATELFDEASHCAHAASSSVLKGEQSNTSVKFGDCAI
                     MKLYRRIEPGMNPELEVGRALTARHFTHSPSLIGALEYVQEAGEPMTLALAQTFVANR
                     GNAWDYTLEQLSRYINGILALDHRKEEAGQPAHDRSNQEPTTSDLLLGYRDSAHLLGQ
                     RTGELHIALAQPSDEAAFTPEPCATSYVQSRVHAMQQSATQALALLRRRLPSLSVTDQ
                     EQAQKVLEQESPLLSRLATLARQPLSALRIRCHGDYHLGQVLYTGEDFVIIDFEGEPA
                     KPLAERRAKCLPMVDLAGMIRSFHYAAHVALRTGEARRPHLPASLDLVSWMEHWYRTV
                     RTAFLRGYRTTAGQAPFSPQSPDEFNLLLDVQMLDKAMYELTYELNNRPDWVGIPLTG
                     LLHSMSASIAIEDADNDDVRNDGAIPRSGGQVRDEVNQ"
     assembly_gap    10022..10121
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<10122..10597)
                     /locus_tag="PK063_00795"
     CDS             complement(<10122..10597)
                     /locus_tag="PK063_00795"
                     /inference="COORDINATES: protein motif:HMM:NF037041.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95597.1"
                     /translation="MITVRDNWKVAFEGSSRAEIEKLLPDFLTASRWFGGKAKTIRSA
                     KLADVLQQEHGDGTMVLALIDVSYLEGGADRYTLPMTAAFDAEADRVKHDYPEAIIGA
                     LTVLQNGTALAGILYDALWHPDCAYSLLDSMGRRGQFRRSIGTLVGSATELFDEAS"
     gene            complement(10622..12658)
                     /locus_tag="PK063_00800"
     CDS             complement(10622..12658)
                     /locus_tag="PK063_00800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014960487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3416 domain-containing protein"
                     /protein_id="HMZ95598.1"
                     /translation="MPSKPASRKKQASSPVLGEGRLRVAIEHVEPQADDGRYPIKRVV
                     GETIIVEADLFADGHDVIQGILRSRHERQEEWLTTPLSPLVNDRWRASFDVTELGQYR
                     YGIMGWVDPFATWQRDMRKRLRARQDVTVEILIGKHLIEQATAPAPDVSRRRLKDIQA
                     RVSRSDLASQALLDLLLEEDTAEIMADCIDHALMSTYDRELIVVVDRPKARFSAWYEM
                     FPRSTTDEEQPHGTFKDCESRLPYIAEMGFDVLYLPPIHPIGETHRKGRNNNPRGDSS
                     SVGSPWAIGSRDGGHTAIHSELGSLGDFEQLVAAAQTNGIEIALDLAFQCSPDHPYVK
                     EHPEWFKTRPDGTIQFAENPPKQYQDIFPLHFETDAYPDLWKELREVVQYWIDHGIRI
                     FRVDNPHTKPFLFWKWLISDVKASYPETIFLAEAFTRPKVMYHLAKIGFTQSYTYFAW
                     RNSKQELTDYFTELTTSSVREYFRPNLWTNTPDILTEHLQHGGRPVFMARLALAATLG
                     SSYGIYGPAFELYENRPQKPGSEEYLDSEKYEVRRWDINRPDSLKEFISLINRIRREN
                     PALHRDESLQFHPIDNEYLLAYSKQSADGSNVVLIVVNLSPHHVHSGWMELNLAALGI
                     EANQPFQVHDLLTQAYYVWQGPRNYVQLDPHSVPAQIFTVRRNLRREEDFDYYL"
     gene            complement(12691..13392)
                     /locus_tag="PK063_00805"
     CDS             complement(12691..13392)
                     /locus_tag="PK063_00805"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95599.1"
                     /translation="MSDLWRETMVAGFRDTVMQIVLVLPRLLALLTFLSLGLLAAWSV
                     KVLTLRVLRTFGFDSFCERLGIVQPLSQAGVRRPVSLVVSGVLFWIVFLLFAFMGVDA
                     MNLPATANLISQIVAFLPNVLAASLVLLVGVLCANFFAEAALIAAVNAQVEEARVVAG
                     LVRWGLLLFTCAMVLTQLGIAKEIVIAAFSITFGGVVLALALAVGLGARHLMREILER
                     RFSQHEHKADQLSHL"
     gene            complement(13385..>14520)
                     /locus_tag="PK063_00810"
     CDS             complement(13385..>14520)
                     /locus_tag="PK063_00810"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95600.1"
                     /translation="GMRQFFPHASALLVNCDAGSQDDTPGLITRLADGVIPVRIVSNA
                     TGSYAHLTREPGFPGRDESIHNFCLTAQRLRPKICLILEGQLRSLSPSWIDHLGRPVY
                     EQGEDYVVPLYRRHRYEGTLATNLLYPLTRALYGKRLRYPSGGAYALSGKFAGDVISQ
                     PTWKGPAAKYSVDSRLTTAALAGGYRVCHTCLGTRDQESTLGAVDLSVLIAQSVGGIF
                     HSMEAYESSWEAIKASSEVPLYGEPESAPDPGPLHTGRMISGFKQGLRDLLPLWELIL
                     SRDTVGQIIALDIQDPEEFRFPPSLWVQTVYDFSLAYHNQTLHREHMLKALTPLYLGR
                     TASFVLETQHGDAGEVERTVETVCREFEAAKPYLVEQWRWRDE"
     assembly_gap    14521..14620
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<14621..14859)
                     /locus_tag="PK063_00815"
     CDS             complement(<14621..14859)
                     /locus_tag="PK063_00815"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95601.1"
                     /translation="MTTVMSKPQGGKSETEVLAPSPELSVSRTDMEWPTDTIDIMIGL
                     LTLNNAGSIEPVLKSIVEGMRQFFPHASALLVNCDA"
     gene            complement(14876..16075)
                     /locus_tag="PK063_00820"
     CDS             complement(14876..16075)
                     /locus_tag="PK063_00820"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HMZ95602.1"
                     /translation="MHSALDEYREVSPKGTVDFLYRLSDLVQGKSFLHLNAVRYGGGM
                     SEVLRRLVPMMVSLGVEARWEVLAGSQEYFVVVTRMLNALQGRDDKLTDDMYQTYANV
                     IERNAKALKLEADMVMVHDHQPAGLVDYRTNGCWLWRCHLDLAQPQRPAWAFLRRYVL
                     KYDAAIFSLSGFAQRLPIPKFLIYPSIDPLSPKNRDMSRSEIAQVLDRLAIPRVKPTI
                     LQVARFDRFKDPLGAIHTYQLVKRHHDCQLVLAGSGVMHDPEGEAVLMELREAGARDP
                     DIHVIQLPPEADLEINALQRSATVVLQKSVKEGFGLTVSEAMWKGKPVVGSTAGGIAA
                     QIVDGVTGYVVHSVEGAAFRIRHLLNNPGLMNRMGAMAREHVRRNFLITRQLGDYLTL
                     LKLLPAA"
     gene            complement(16124..17803)
                     /gene="treS"
                     /locus_tag="PK063_00825"
     CDS             complement(16124..17803)
                     /gene="treS"
                     /locus_tag="PK063_00825"
                     /EC_number="5.4.99.16"
                     /inference="COORDINATES: protein motif:HMM:TIGR02456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047471 - maltose
                     alpha-D-glucosyltransferase activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="maltose alpha-D-glucosyltransferase"
                     /protein_id="HMZ95603.1"
                     /translation="MLNQDPLWYKDAVFYELHVRAFYDGNDDGVGDFPGLIQKLDYLE
                     WLGVDCLWLLPFYPSPLRDDGYDVADFRSIAASYGTTDDFRRLLEEAHRRGMRVIVDL
                     ILNHTSDQHAWFQAAKASPDAPTRNYYVWSETDQKYPRARIIFVDTEKSNWTWDHEAQ
                     AYFWHRFFSHQPDLNYDNPEVRRAMIQVMEYWLDQGLDGFRCDAVPYLFEREDTICEN
                     LPETHQYLKDIRSSIDQRYKGRVLLAEANQWPSDVRPYFGDGDEFHMAFHFPLMPRLF
                     MGVRSEDRQPIVDMFKHTPDIPSACQWCLFLRNHDELTLEMCTGEERDYMYYAYARDP
                     QMRRNIGIARRLAPLLDNDRRKVELLNSIVFTLPGSPIIYYGDEIGMGDNIHLGDRNG
                     VRTPMHWTADRNAGFSKADPSQLFLPVVADAVYGYQAVNIDAQKQATHSLLNWMRRMI
                     AIRKKHKVFGRGTLQFLSPANEKVLAYIRAYEQETLLLVHNLAGSSQAVELDLSRYKD
                     VVPEELLGESRFPTIHEHPYVLTLGPYSSYWLHLPAVRSPTTAYSMEWSAI"
     gene            complement(17807..18481)
                     /locus_tag="PK063_00830"
     CDS             complement(17807..18481)
                     /locus_tag="PK063_00830"
                     /inference="COORDINATES: protein motif:HMM:NF039842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5752 family protein"
                     /protein_id="HMZ95604.1"
                     /translation="MVLTADAPFAFIGCSELQESIAHQADDEKELAELIEEVPLDSIH
                     FHTHSYFLRHGLIEGTYPNDFAQWVVMQIGDHVLGERLAVLDPFDYPDLENLREELIS
                     IIDDHLSRSPIIPRVVFGQPFHFKRSRILEVPIGLEARTLQEFRDIVTDIDVSSIYYH
                     MFEAHFRLRRAENDFSAWLRTSLKLTNLADRIRSINPYQGSLERLRSKLISACDDFLT
                     SESAKS"
     gene            19136..19852
                     /locus_tag="PK063_00835"
     CDS             19136..19852
                     /locus_tag="PK063_00835"
                     /inference="COORDINATES: protein motif:HMM:NF016041.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sterol desaturase family protein"
                     /protein_id="HMZ95605.1"
                     /translation="MLNPYLLFWSIGLLFFVAEWLRPARKITYRAVFWRDLLALGAYN
                     LSFLLVVQVTDRIPVPQYLPVALYNLPTAGKLLLFYIVEDFGLYWVHRLMHTRVVWPI
                     HRWHHSPTSLYWLAGIRTTIPHIALFNVTYVAALPLLHDASGWAFQVIMVEHIVRNNW
                     MHVNVTWKSSWLEWVFVTPRYHHIHHSSDPAHQVKNLGALLTIWDRLFGTYYNPDDVT
                     GELKFGLSERVNPIRLVIGV"
     gene            complement(19990..21303)
                     /locus_tag="PK063_00840"
     CDS             complement(19990..21303)
                     /locus_tag="PK063_00840"
                     /inference="COORDINATES: protein motif:HMM:NF023301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase domain-containing
                     protein"
                     /protein_id="HMZ95606.1"
                     /translation="MRIMTVSEILFSSRPHLLYTPAMRTRRMSLLLLSLAVPTLFSGC
                     ETTDKMLGAAERAVGSTTGRTVLDIVHGKDPADIARQRVEQYGRDPQALLRDLRAIQR
                     DFQALMAALTGEVGKKWGTKEVKLPEQKKYVKYTQNYRSRAIVDFDAGNILIETLDEK
                     DPRASLKNAVVTTLLTPNDPRSVDLFSDKEITLTGDKEPYLLGLVVNQAGKPVRTPTE
                     AEQFAESLLAKSTTRPVEQENGAKTAHLVNIPMVTNFSHKQAEKYRTVVAQFAERYQI
                     SPSLVFAIIRTESNFNPFAVSSAPAYGLMQLVPTSGGRDAYRKAKGEDKAPSRDYLFD
                     PDNNIELGTAYLNVLTYSQLDDVTDMVSREYCVISAYNTGAGNVFKTFAKDQRTALQQ
                     INGLQPSTLYDRLRSGLPYQETRDYLAKVVGFRKQFVVIGENGAQ"
     gene            21449..22051
                     /locus_tag="PK063_00845"
     CDS             21449..22051
                     /locus_tag="PK063_00845"
                     /inference="COORDINATES: protein motif:HMM:NF017319.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HMZ95607.1"
                     /translation="MNTRASAAVWCWVIVLLMTLAPSPGRAAQTPTEAVQVTMKDLLY
                     LLTELKETSRSAQRQWEIEQVVRRAFNYEEMAERALGEGSEKTTIADRRQFTRLFVQV
                     LRDDLADKLRDYSLPQVAYLSEQGDGTGTQVLVAPAGREVDTKIEFSVVERSGRWLIN
                     DVSIDGASIVATYQTQFSRILREGSFSDLMEFLKQKAVVA"
     gene            complement(22218..22922)
                     /locus_tag="PK063_00850"
     CDS             complement(22218..22922)
                     /locus_tag="PK063_00850"
                     /inference="COORDINATES: protein motif:HMM:NF012422.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ95608.1"
                     /translation="MSDLHACHAPITVAIVTKNHLVRIGLQAALSAQQHIQLVGEANG
                     AHEAETLVSREQPHVLVIEMETDLDVRELVRSVKTSVPKTRIILLSNIEDKAHIVGSV
                     SSGIDGIVLTIQPAVVLLATISHVCGLPDATTLYERRTRRRLHCTESSIDDDSPPSLS
                     STSPDTALTGREREIVYLIGQALSNKDIAERLCISSVTVRHHLTSIFGKFDVNSRQKL
                     LLRAYEYGLLKVHAHH"
     gene            complement(22946..23353)
                     /locus_tag="PK063_00855"
     CDS             complement(22946..23353)
                     /locus_tag="PK063_00855"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95609.1"
                     /translation="MMLCPATHCGQMMETDVRAGYDPDSGLECLFCPRCGHRGMKART
                     GVQLLFTGQHEYVFSYGPSLSHLKIVLSTVAINLFRTQGMPPTQLAAHVADWALLMGQ
                     VCGTVRFSGDLILSSCYEYCRREATKSPAVSSL"
     gene            complement(23399..23716)
                     /locus_tag="PK063_00860"
     CDS             complement(23399..23716)
                     /locus_tag="PK063_00860"
                     /inference="COORDINATES: protein motif:HMM:NF022603.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2934 domain-containing protein"
                     /protein_id="HMZ95610.1"
                     /translation="MPERNAQAPAGDEPIRNISRGATSRSIPKRKDRLQPSPQAETTD
                     TAEDIRTRIEKLAYARYQQRGQQDGYDYEDWLEAERIVQGESAPQSGEGSGRSGTHAL
                     HSA"
     gene            complement(23774..24202)
                     /locus_tag="PK063_00865"
     CDS             complement(23774..24202)
                     /locus_tag="PK063_00865"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95611.1"
                     /translation="MSPTMHPVKQAGRSRVMIVDSAMQFGLKLADCLATRGYHAVLVR
                     DLESTLPQLGEIQPAAILFSHDSGGSHCDTPGMDALRALNALCPQAPVLALSEPVHPV
                     LSGESRSGDTLSAKSASPPLEHPVEAVLLTTLGIPCVRLQ"
     gene            complement(24199..24504)
                     /locus_tag="PK063_00870"
     CDS             complement(24199..24504)
                     /locus_tag="PK063_00870"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95612.1"
                     /translation="MTTLAEIEGLITRELTRRGACTLEALAQQLQTCTWNQVFMAVDI
                     LSRRGTLVLRPLPEFQYTVSLAGSGSSTLRHLIPVTAGKPSLGVAAVDQIMNKEGQR"
     gene            complement(24749..25438)
                     /locus_tag="PK063_00875"
     CDS             complement(24749..25438)
                     /locus_tag="PK063_00875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ95613.1"
                     /translation="MTGPFLDQTQQMEPIVTKILVVDDHAVVRQGVKQILNEQFQGAV
                     IGEARNAEEMIDRIRKFTWDIVVLDVGMPGKSGLDALKELKQVCPKLPVLVLSAYPED
                     QLARRMLKAGASGYLTKDSAPNELVQALKKILGGGKFVSASMAELLVANLNEEAGRPQ
                     HELLSDREYQVMCLIAVGKSLKEIADDLCVGISTINTYRARILEKMQFKNNTELTHYA
                     LENRLVNRLVS"
     gene            complement(25462..27705)
                     /locus_tag="PK063_00880"
     CDS             complement(25462..27705)
                     /locus_tag="PK063_00880"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ95614.1"
                     /translation="MTNRPIHVLLIEDNPGDIRLVRELFAQTGNGQFTLTHVGRLDAG
                     IRCLSESLIDVILLDLSLPDSQGIETLIRMHAAAHGIPIVLMTGLEDEELGLHLIQAG
                     AQDYLIKGQTSAPLLARALRYAVGRKRLEEELREQTRFLQSVLNSMADGVVMADETGT
                     FRVWNPAAEQILGSGPAKRTVGHWSEDFTIFRPDRVTPYPAEDIPLARAIRGESVTGS
                     TLFLKRRSQGNDLWLDVSARPLRDEMGLIKGGVVVFRDITEARRTDEALRDSENRFRA
                     IMDNSPALIFLKDLEGRYLQANRQFETVSHLANKDLVGKTDEEIFAPAQAAVFRENDR
                     KVLQADAPMQFEESALHDDGPHTSIVVKFPLRNAEGRCYALCGIATDITDKQRAEEIR
                     QQLAKDRLLLLESTGEGIYGLDRQGRCTFINSAASRMLGYSPDELLCQDMHERIHHSS
                     PDGGIYHRTRCHIHETLVDGRGRKVDDEVYWRKDRTSFPVEYSSFPVIEQGKVTGAVV
                     VFLDITDRKRAEQQLTASHAQLRKLTARLESVREEERILIAREIHDELGQALTGVKLE
                     LSLLQDQLPSVPPTVHSRLESISGLVDATIQSVRRIATDLRPIVLDQLGLIPAIEWQT
                     HEFQSRTGIECRLDIYLRSACLSQTASTAMFRIFQEILTNVVRHAKASVVKITLQEQG
                     GGLVLEVQDNGRGITETELADPQSLGLVGMRERALLLGGSITFAGNAGSGTIVRVRIP
                     LDQPAQE"
     gene            complement(27702..28166)
                     /locus_tag="PK063_00885"
     CDS             complement(27702..28166)
                     /locus_tag="PK063_00885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ95615.1"
                     /translation="MVVPELVKPIEILLVEDNPGDVRLTIEALKEAKVINHLTVVKDG
                     MEALAFLRRQGSYTAAPRPHLIVLDLNLPRKDGREVLADIKADDSLKRIPVVVLTTSQ
                     DEQDVLKSYNLHANCYITKPVDLDQFVRVVRSIEDFWLGIVVLPVSHQPGAV"
     gene            complement(28198..29985)
                     /locus_tag="PK063_00890"
     CDS             complement(28198..29985)
                     /locus_tag="PK063_00890"
                     /inference="COORDINATES: protein motif:HMM:NF014763.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ95616.1"
                     /translation="MIALPTTTVQTTAFDSSSRWTERILPILLFLCFFIATALGLYAL
                     SFLRAMLVAERGDELAMNAATVAETVDRVLFERYGDIQLFANDGVIRDGSSEERTARL
                     QHYHQLYWYYSWLGITDADGTVIAATDMRPASGPPPLNRAAFDAVRRSGTIYLEPVVP
                     SAMPPQQKAVGFMAPIYGPRGEFRGVVASRVPIDNLRSIFEQEGRLRYGKDPYDWLLL
                     TRDGAIISEKQTSAESPKGSAILDIPSRSRAASDRNQSGFVEEVHHRQGHSVVTGYAS
                     TRGYRDFPGFDWIVLFRQTHDQVYAPVDRLLWTVGGIGLLVILPLTGFGILVSWKLGR
                     ERSELLKTRQDLEKSVAELGRSNADLQQFAYVASHDLQEPLRMVSSYTQLLAKRYRGQ
                     LDADADEFIAYAVDGATRMQKLIQDLLAYSRVSTGSQPFEPTPMGAVLSYAMDNLLSA
                     IKESQAVITHDRLPTVRGDAKQLAQLFQNLLSNAIKFHGDQPPRIHISAQRREDEWLF
                     SVRDEGIGIDPQFAGRIFVIFQRLHTRAEYPGTGIGLAICKKIVERHGGRMWVESETG
                     KGATFWFSIPDPPQQPSVTRSEGATTGVA"
     gene            30141..30557
                     /gene="arfB"
                     /locus_tag="PK063_00895"
     CDS             30141..30557
                     /gene="arfB"
                     /locus_tag="PK063_00895"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alternative ribosome rescue aminoacyl-tRNA
                     hydrolase ArfB"
                     /protein_id="HMZ95617.1"
                     /translation="MLSISTHVSIPDEEIELTAVRAQGAGGQHVNKVSSAIHLRFDVR
                     ASSLPPFYKERVLELRDHRVSRDGVIIIKAQDSRSQERNRALALERLRELIQQAAIPR
                     IPRRPTKPTKGSKKRRLEDKSKRGQLKSLRSRPHEQ"
     gene            complement(30629..30946)
                     /locus_tag="PK063_00900"
     CDS             complement(30629..30946)
                     /locus_tag="PK063_00900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HMZ95618.1"
                     /translation="MGNKLYVGGLPYAATESQLSNLFSAHGTVESARVITDKFTGQSR
                     GFGFVEMSTAEEAKAAITALNGSDMDGRQLTVNEAKPQEPRSGGGGGGRFGGGDRGGR
                     NRF"
     gene            complement(31240..32109)
                     /locus_tag="PK063_00905"
     CDS             complement(31240..32109)
                     /locus_tag="PK063_00905"
                     /EC_number="1.14.19.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016717 - oxidoreductase activity, acting
                     on paired donors, with oxidation of a pair of donors
                     resulting in the reduction of molecular oxygen to two
                     molecules of water [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA desaturase"
                     /protein_id="HMZ95619.1"
                     /translation="MQQVSPTPVPAHIVHRVHHKFWTYLLFWSIVAGSVICVPGYGIL
                     YGYSWLDWTMFAVLYLITGLGITVGYHRLLTHRSFECPDWVKACLLVAGGWALQNSGA
                     KWTADHLRHHAHCDDPADPYNAKRGFWYSHCGWLLNPVPCNDERFGSRVMQDPVAMWQ
                     HRNYAAIVVVGLALPFVIGFLHNGWQGGIGGFMLAGVGRTFAVLNSTFCINSVCHIWG
                     EQPYGTSDSSRNSWLVSLLTFGEGYHNYHHTYPSDYRNGPLWYNFDPSKWLIYTLSKL
                     GLASSLRTASPGN"
     gene            32319..32669
                     /locus_tag="PK063_00910"
     CDS             32319..32669
                     /locus_tag="PK063_00910"
                     /inference="COORDINATES: protein motif:HMM:NF013035.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine rich repeat-containing protein"
                     /protein_id="HMZ95620.1"
                     /translation="MPTGYPRKATSMVLWSCVVIGLSGLYAPVNAAPDPASTGQEQPA
                     ATSEEPGSSGKRPEGQGRGGRPGRKACADDVKKLCAGVKAGEGRIMQCLREHTQELSP
                     ACADMMQQRGKHRP"
     gene            32833..33213
                     /locus_tag="PK063_00915"
     CDS             32833..33213
                     /locus_tag="PK063_00915"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ95621.1"
                     /translation="MSDTTRQEQFSVDLRQHPRLRVPAPFACSLSRLGLAKWLGRGGE
                     GIGVVFDVSMRGAKVMSEAGIQRGDRVSVSLSLPNQVSPMTVEKATVRWEREQVYGLE
                     FVDLSPVAEMRLRKFISLATKPAA"
     gene            33388..34326
                     /gene="lpxL"
                     /locus_tag="PK063_00920"
     CDS             33388..34326
                     /gene="lpxL"
                     /locus_tag="PK063_00920"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:TIGR02207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LpxL/LpxP family Kdo(2)-lipid IV(A)
                     lauroyl/palmitoleoyl acyltransferase"
                     /protein_id="HMZ95622.1"
                     /translation="MSNPQANHKRRQPRSVYHPMYWPTWVGITLFRLLSWLPYHAQLA
                     FGRQCGRLLHGLLTKRRDIVRVNLALCFPEQSPEERNRVALHSFESMGMGVLEIAMAW
                     WAKDPRAHCECTIKGLEHIRDALHRGRGVLLCGAHLHAAELAGRFMALEQPVAIVYRP
                     QNDVVADMVANRCRSRYYSELIQHRDMRGILRALARNQVVWYAPDIDAGSKRSVFAPF
                     FGVPASSLTATSRLAKVSGAAVVPCFYYRRADGSGYDIEVGEALDHFPSGEMIEDATR
                     VNRLIEGAVRRVPEQYFWQHRRFKSRPPGEPPLYRR"
     gene            34473..34850
                     /locus_tag="PK063_00925"
     CDS             34473..34850
                     /locus_tag="PK063_00925"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ95623.1"
                     /translation="MDQDKQVSPVRIELRQHRRCPVAETCLLSFAPFAPTLSFNGDAE
                     GEGTVLNLSPGGCKISSEAGVKVGDAMSLIILLPGETAPTAVDLALVRWGKDLSFGVE
                     FVSMGTAEQDRLRQFLASAAVSE"
     gene            34897..35229
                     /locus_tag="PK063_00930"
     CDS             34897..35229
                     /locus_tag="PK063_00930"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ95624.1"
                     /translation="MEETRTLRKSRRVAADCRLEFVGEDEIEGEAEVLDLSSTGCMAK
                     SDQAMPPGLRMKVSLLLPDGHEWPVRIEEAVVRWARGGEFGVEFLVMRPPQLQRIQQF
                     VIKHRPLG"
     gene            35422..36201
                     /locus_tag="PK063_00935"
     CDS             35422..36201
                     /locus_tag="PK063_00935"
                     /inference="COORDINATES: protein motif:HMM:NF014460.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HMZ95625.1"
                     /translation="MFTWVGRKTIAGYAYLAALATLFAQAVFDLIIPPKQGRGETFRV
                     LVRQILFTGVDALPVTTVIALLLGIIIVTQAGTQLPRLGAGGLVGSIIVVTVIRELGP
                     LVTAFIVVGRSGSAIATELGNMSVTREVVALRLMGIPISRFVIMPRMVGMVLSMVCLT
                     LYFDVVAVFGGYLVADAQLTIPLDAFAESVIRALSTTDVLMTAIKGLGFGSAVAAVCC
                     YHGLAVRSSYTEVPQQTTRAMINSFVLCLLIDVVVTVPLYL"
     gene            36198..36929
                     /locus_tag="PK063_00940"
     CDS             36198..36929
                     /locus_tag="PK063_00940"
                     /inference="COORDINATES: protein motif:HMM:NF012235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HMZ95626.1"
                     /translation="MSEAAIIFDKIRAPMLGGDLWLELDLKIMAGECVVCVGPSRAGK
                     SLMVELAAGLIAPESGRVLVLGQGWSEVSDDAPGSVRLKVGVVLQQPGLLSNMTLFNN
                     VLLPLRYHRSAMPDRHREQVVMGELERLGLASLRDRFPAELNQGEARRGAIARALILE
                     PEVLLLDDPVAGLDADMVLGLKSSIDERRAQRPLTVLAALRTCSPFVDAADRLIVLRD
                     GHVEADGTRDTVRDLAPEALRRYVE"
     gene            36962..37954
                     /locus_tag="PK063_00945"
     CDS             36962..37954
                     /locus_tag="PK063_00945"
                     /inference="COORDINATES: protein motif:HMM:NF014523.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MlaD family protein"
                     /protein_id="HMZ95627.1"
                     /translation="MMHYSHRLSSGRLAQIVGTFVLIPAVILAVAGFWMSRTEHLFES
                     KYLLKASLSKSYGLEPGAPIVVSGIRIGRVKQVDLNDRGTVDLTLQLLARYQDMVKEN
                     SELHITKSGVVVGQTQVDIAMGTASSPVLSEGSIIRAVEPRDIGDLLNEVEPVLMAVK
                     QTLLRVETITQDMQGGLKAGGKALEQVALATQELPAVVASVQRTIASVEQTATALPAM
                     TGSIKRTLSMVDRVTADVQQTTGRLPAILDSAQTTLTSVKRLSDSVSEVSQELGPIIH
                     SAETTLADMSILVRGAKQTFPFNRFVQNAGPAPKESPPPSREGTQSLRGDQLRR"
     gene            38113..38910
                     /locus_tag="PK063_00950"
     CDS             38113..38910
                     /locus_tag="PK063_00950"
                     /inference="COORDINATES: protein motif:HMM:NF024816.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ95628.1"
                     /translation="MRGDLTRAAEEYEAARRMAESLDDTQGLIVAINDVGRVALRRGD
                     VPRAVSSHERAVALAQQRGEPDLLIASLTDLATAEHQSGALQEAEHRYEQALDLAQQR
                     GDRSAEATIRNNLGLIRQAKGDVEQAAQLFRQALALNQALGNLESEASNHVNLGMLAE
                     ARHEYDAAEREYERALELDKTAEQRMEIAADLLRLGKIADRRGFPDRGQTYSERAYQS
                     YLAQDAFAEARSALSQAVACAKKLERAGDIARLERELTRLTAVHPAR"
     gene            complement(38939..41248)
                     /locus_tag="PK063_00955"
     CDS             complement(38939..41248)
                     /locus_tag="PK063_00955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GspE/PulE family protein"
                     /protein_id="HMZ95629.1"
                     /translation="MQPKAPLPSGDATLKSGNAEQVKRISGQILAAADVDQILLDLRH
                     EILGCFDAEDLTLFVVDSEKKEIFSKIPHLDTVQEVRTPITEQSLAGFCAKYLRPVNV
                     GDAYSLVELSAIHPSLTHDATYDKSTGFKTKQVLAYPVVAENKYLMGVIQLLNKKSGG
                     RFTRKDEECVAEIAKSLGTAFYTLRKTSKKPPSKYDYLLTNGKISQHDLDVALAEAKK
                     GTTDIESLLIEKYKIPKAEIGKSLANFHKCPYIEYNERTIVDIELLKNLNVDYLKKNH
                     WMPLKRDRAAIEILTDDPGDLDRVQDIKRTFPGLNIRFAVSLRRDISLFLASTTGTPD
                     VTNKMNENVSDILGELVNESQLEAQEEASAAGLDENDNAIVRLANQIIADAFRQGTSD
                     IHIEPYGEKRDTLVRFRVDGDCFEYMKIPPSYRRAIVSRLKIMASLDIAERRKPQDGK
                     IKFKIGENKEIELRVATIPTAGYNEDVVMRILAASEPLPVDKMGFSERNLREIKSIAE
                     KPYGIILCVGPTGSGKTTTLHSVLGYINTPDIKIWTAEDPVEITQYGLRQVQVHAKIG
                     FTFAAAMRAFLRADPDVIMVGEMRDKETADTGIEASLTGHLVLSTLHTNSAVETITRL
                     LDMGCDSFSFADAMLGVLAQRLARRICKDCKEAYQPSKEEYEELRLGYGPDYWDALKV
                     PFDANFRLYRGKGCDACNRTGLKGRVALHELLLGTDKMKKLIQNKAKTDEMLHAGMED
                     GMTTLVQDGIQKVLQGHTTYKEVKAVAIK"
     gene            complement(41487..43193)
                     /locus_tag="PK063_00960"
     CDS             complement(41487..43193)
                     /locus_tag="PK063_00960"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: protein motif:HMM:TIGR00409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HMZ95630.1"
                     /translation="MRVSETLIPTLREDPGEAETVSHRLMLRAGLIRKVAAGIYTYLP
                     LGLRVLRKIERIVREEMNRAGAQEVLMPVASPAELWRETGRWDFYGKELLRFKDRHER
                     DFCLGPTHEEVITDLFRREVRSYRQMPLNFYQIQTKFRDEIRPRFGLMRGREFIMKDA
                     YSFDRDEAGARLNYQKMYDAYNRIFARCGLTFRPVEADTGLIGGSSSHEFMVLAETGE
                     ETIVYAEGGTYAANVERAEVLPPDVSPLPALRPLTAVSTPGRRTVEEVTKFLTIAPSQ
                     LVKTLLYTTGKETVAVLVRGDHEVNEIKLKRLLGATDIELVAPELIPKLTGAPVGFAG
                     PVGLKQIRILADWSVKAMANFVVGGNQVDTHFTDVNWERDFTVAQFSDLRNAQAGDLS
                     PRKDGVLKTAKGIEVGHVFMLGTKYSQAMKATFLDAQGQEQLAVMGCYGIGVSRVSAA
                     SVEQNHDAKGIKWPIPIAPFHVTLLPLSQSEPVLQLAESLYRAMEQAGIEVLWDDRDE
                     RAGVKFNDADLIGAPFHLVIGEKGLAQGQVELKLRHTGETKKIAPDQVIPTLTALLQA
                     AS"
     gene            complement(43200..44591)
                     /gene="rseP"
                     /locus_tag="PK063_00965"
     CDS             complement(43200..44591)
                     /gene="rseP"
                     /locus_tag="PK063_00965"
                     /inference="COORDINATES: protein motif:HMM:TIGR00054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HMZ95631.1"
                     /translation="MGTTFAWSPDVVSMLTHWALPFLVVLGVLVAFHEAGHFLAARWV
                     GVKVLKFSLGFGPKIFGRQIGETEYLLSIVPLGGYVKLFGEDEHEPLTPEDKKRAFVH
                     QSLWGKTLIVAAGPIFNFILAYLIYTAYIGLGYTLPVPSFKDIIPEIEAVLPGSPADQ
                     AGLKPGDRVIRVNEKEISTNAELLKYIAQSNGKQLTLDLTRGQQIKTVLVTPNKTTVQ
                     DNGKATTLFQLGIEERAPVITAVIPGSRAQAAGLVAGDRVLRIDGHDIFTWSQMTALV
                     RENPNHALQFEIQRNGSAQSVSVTPMGEKATVDGKPAEIGKIGISAQNQTILQTNEPL
                     KAPLLGAQATWGWTELTVVGIYKIITGDISRKNIGGPLTIAKTAGDAAEQGTSSLVFL
                     MAMLSINLGVLNLLPIPILDGGHLLFFFIEAIRRKPLEDRQRELAQQVGLVLLVGIMI
                     FAFWNDIERLISP"
     gene            complement(44617..45777)
                     /locus_tag="PK063_00970"
     CDS             complement(44617..45777)
                     /locus_tag="PK063_00970"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0030604 - 1-deoxy-D-xylulose-5-phosphate
                     reductoisomerase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070402 - NADPH binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HMZ95632.1"
                     /translation="MKNIVILGSTGSIGTNTLDIVERFPQEFRVIGLTAGSNDEKLEA
                     QIRRFRPAFAALASEPAAAKLRQRCADLPVKILSGNEGVAQVAQSPDAELVISAIVGG
                     AGLLPTLAAIKAGKQIALANKEPMVMAGALMQAEAHKHQVRIFPIDSEHSAIFQSLEG
                     HRREDVKRIILTASGGPLWGFSREQLQDVSPERALQHPNWKMGSKITIDSATLMNKGL
                     EVIEARWLFDIPETQIEVLVHRESIIHSLVEYRDRSMIAQLGLPDMRTPISYAMRYPE
                     RMPLDLPSLDLTEVSTLTFFKPDHDRFPCLQLGYDALRIGGSMPATMNAANEVAVEAF
                     LQNGIRFLDIPDIIRSTMDAHQPRPIDGLDDALEADRWAREKAESLVHALTR"
     gene            complement(45810..46658)
                     /locus_tag="PK063_00975"
     CDS             complement(45810..46658)
                     /locus_tag="PK063_00975"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: protein motif:HMM:NF013327.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HMZ95633.1"
                     /translation="MSPTVDKARPRSSSETVRRVMAAVVFLPIFYILVHDLGPIAFFG
                     LVALSGMLAVAEFYRLHLAQAPWPWWSWAGVVATGLLLSSIQWPTIVADRTVLIATVV
                     MALCMPLLSGKALRDSLNDGMVLVMGVLYIGLLLGYLLLIRAMPDGALLIFFVVLVTW
                     AADTGAYIAGKSVGRHPLAPVVSPKKTYEGLAGGILLACLGAVAARAWFLPSISLVDC
                     LVLGVILTLAGLIGDLAESAMKRSTGFKDSGALIPGHGGMLDRLDSLLFTGPAFYYYV
                     AIVTTV"
     gene            complement(46699..47484)
                     /locus_tag="PK063_00980"
     CDS             complement(46699..47484)
                     /locus_tag="PK063_00980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HMZ95634.1"
                     /translation="MSDPRSRDIEPAPDSDLLSQLDPDLLPKHLAVIMDGNGRWAELR
                     GLPRIAGHQEGIKSVRELISLSLDLGIKVLTIYAFSQENWNRPAQEITALMGLLEHYL
                     STERSSLVEKGVRFQTIGRVTALPPSALRWVRTTEQETAHLDKLILNVALSYGGRAEL
                     ADAAKELARSVQEGRLSLEQIDERAMQQALYTHDLPDPDLLIRTSGETRISNFLLWQL
                     AYTELYFTPTLWPDFRRRETLVALIEYQRRERRFGRVFSSVSS"
     gene            47677..49119
                     /gene="tldD"
                     /locus_tag="PK063_00985"
     CDS             47677..49119
                     /gene="tldD"
                     /locus_tag="PK063_00985"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease TldD"
                     /protein_id="HMZ95635.1"
                     /translation="MTNNETGALARFGVTDRDIEQALGRVKVSAVDYADLYFEYCQSE
                     SVSMEEGIVKRATKSVGQGVGVRATAGEKTGFAYSDELTAKDLNIAADTARYIANSVQ
                     GTAPVPVTHRPPLARNLYPHDRATIEVATRDRVTLLNAIDAEARRYDPRIKNVMAAYN
                     TEYKVMLVATSDGLMVGDIQPLSRLQVTCIAEENGNRQVGTFGGGGRIGLEYFQNDQR
                     YLHFAREAAREAILNLSAVDAPAGVMPVVLGGGWPGILLHEAIGHGLEADFNRKKTSA
                     FSTLMGKKVASEVCTIVDDGTLPFRRGSLNVDDEGTPTSRTVLIEKGILRGYITDKLN
                     ARLMGIPVTGNGRRESYQSVVLPRMTNTFMLAGESDPQDIIKSVKKGLYAVSFGGGQV
                     DITNGKFVFSASEAYLIEDGKITRPVKGATLIGSGPDILKQVSMVGHDLKLDEGIGTC
                     GKEGQSVPVGVGLPTIRIDEITVGGTKASS"
     gene            49116..50474
                     /locus_tag="PK063_00990"
     CDS             49116..50474
                     /locus_tag="PK063_00990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallopeptidase TldD-related protein"
                     /protein_id="HMZ95636.1"
                     /translation="MTRMIGEQDYTTVAQDLLTRASKQGATAADVMVADGETLSVQVR
                     MGAVDRLTKAREKRLGLRVFFGQRSASASTSDFSRDSLERFVQETCALAQAVVEDPVS
                     GLPEPGQFATELPELHIHDSTKLQTDEQIALALRAERAAFAADPRITNSEGGECDSSS
                     GRIILANSHGFLGHYANSSFSLSVSPIASDAAGMQRDYWYGVNRSFAKLESPEAIGQE
                     ATRRTVRKLGARKAATGRVSVIFDPEVAGSLLSHLCSALSGYALYKGASFLIGQLGQQ
                     IAPDFVTIYDDGRMPGGLGTRPFDGEGLPTRKQAVVERGRLTSYLLDTYSGKKLGLPS
                     TGNAARSIGESPSAGPTNFYMVPGTTRPEDILASVKQGLYVTDLIGFGINMVTGDYSR
                     GASGFWIENGELAYPVEEITIASNLKQMYSAIETIGSDLVFRGRIASPTVKIAEMMVA
                     GN"
     gene            50495..51049
                     /locus_tag="PK063_00995"
     CDS             50495..51049
                     /locus_tag="PK063_00995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HMZ95637.1"
                     /translation="MQRLMASMLGALLTIPAIGMAAEFHVTSPTIKDQSTIGSEHVFN
                     GFGCTGQNVSPALQWEHAPKDTKSFAVTVYDPDAPTGSGWWHWLIFNLPPGTTGLSAG
                     AGNPDSAGAPAGSIQSMTDFGQPGFGGPCPPPGDKPHRYIFTVFALKVDQLPLKKDAS
                     GAMVGYYLNQNALGKASVTGLYGR"
     gene            51085..51540
                     /locus_tag="PK063_01000"
     CDS             51085..51540
                     /locus_tag="PK063_01000"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95638.1"
                     /translation="MALDAEQGKIMLQLITSRYEDRHWRKKIEKTLSLPQSGVGDERQ
                     QQMFLYLKLNLKAYKSRRADPDDWILGGYATKEVIDRAKFQPHLVGQGITAEDVAFLG
                     VDPGPDVDEAWWEDMLVAWFGAPEDEEATEATEEESPSETAAESHPART"
     gene            complement(51600..52271)
                     /locus_tag="PK063_01005"
     CDS             complement(51600..52271)
                     /locus_tag="PK063_01005"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HMZ95639.1"
                     /translation="MSSPHIALQELADSLHDCQRCPLAKLGRRQVVFGVGNPQASVMF
                     VGEAPGFHEDQKGEPFVGAAGQLLNELLQSVGLSRADIYIANVIKCRPPNNRDPEPPE
                     VDTCKPFLLKQIALIRPKLVCSLGNWATQTLLERKVGITRVRGQAFYMKDFVLFPLLH
                     PAAALHQSSMLQPLREDFQKLKEFLDRHNQPAPAKEQEVASAARTLEIERPSSPAQQM
                     DLFGS"
     gene            complement(52366..53664)
                     /locus_tag="PK063_01010"
     CDS             complement(52366..53664)
                     /locus_tag="PK063_01010"
                     /inference="COORDINATES: protein motif:HMM:NF013739.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HMZ95640.1"
                     /translation="MLILGGGIAGLTAARSLAAKGHAVTVIEQGAHLGGRMWHAPPPI
                     LLEAHGATWSLLKTLGQDAVTRPLRHTPLEFLQSTGARIQFLHLPLPSPLNTLLGTTL
                     FQGLSMRDRWHLLSFLERTWEQDPPLPNDLDSRVADEWLTSIGQSETARHGVWNSLAR
                     LLLGAALEDISAGLFMRTLRRCFLTGARATKLIVPPQGVDSFLLAPLTRELDRLGVRV
                     KLNATATQVRFSHNRVTEVELADRTRLTADWYLSALPPQRLTPLLPERVVTHYAYFQQ
                     LSRLSESPLVMVRLHLDQPVRQTQLILLEGKTFHWIIRHPDEERHEQTSVLWAQAVGE
                     PSLLPQSTEELVRLAADAMAAAFPTTSPPRILDFDVMRLASAMLASKPGTHQYRPIST
                     SPFTNFFVAGAWTDTGWPANLESAILSGHRCAEAISTRPS"
     gene            complement(53673..54548)
                     /gene="hpnD"
                     /locus_tag="PK063_01015"
     CDS             complement(53673..54548)
                     /gene="hpnD"
                     /locus_tag="PK063_01015"
                     /EC_number="2.5.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA];
                     GO_process: GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="HMZ95641.1"
                     /translation="MMTPTEAQTYCTTLTKKSGSNFYYSFLFLPKARRDAMYTVYAFC
                     KEVDNAVDEPPPGSHPQEELARWRRELSAAYEGTPTLPVTISLARHVRELSIPQAYFE
                     ELIKGVEMDLTTTRYATFEQLSLYCYRVASVVGLICLHVFGTTSPRAQDYAVNLGMAF
                     QLTNILRDLGNDAECGRVYLPQEDFTRFGYREDDLLHRRYKPEFTELMIYEVGRAKEF
                     YAKAARALESLPREERQALTVAEIMRGVYSRILQRIEQSGYRVLGDRVTLTPSHRLAV
                     AAGVWLRSRLLSSAP"
     gene            complement(54545..55486)
                     /locus_tag="PK063_01020"
     CDS             complement(54545..55486)
                     /locus_tag="PK063_01020"
                     /inference="COORDINATES: protein motif:HMM:NF013648.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-binding protein"
                     /protein_id="HMZ95642.1"
                     /translation="MRICSLVPGATEVVAALGLADQLVGISHECDFPPQLSHVPVMVR
                     ARIESRSLSSAQIDAQVSTMLSAGEGLYELDERGLLAAKPEVLITQNLCDVCAITPTQ
                     LTGILRKLAPPPRLVTLNPRRLDDILLDIATLGNALGQAETATRFLSQLRGRLDAVHA
                     RIEKESLRPRVACLEWLSPLYTAGHWVPDMVAAAGGIDALAEAGAASHKIDWDVFAAS
                     EPDVIVLMPCGFTVARTKMELASLTSRPEWKDLPAVRRGQVYLVDALSYFSRPGPRLI
                     DGVEQLAAIFHPACFNHGLPEAVEQLTSDDIPTSMTR"
     gene            complement(55483..56190)
                     /locus_tag="PK063_01025"
     CDS             complement(55483..56190)
                     /locus_tag="PK063_01025"
                     /inference="COORDINATES: protein motif:HMM:NF024811.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HMZ95643.1"
                     /translation="MSELRALIFDFDGVIADTEPLHFAALRQVLAGIDISLTEQEYYT
                     DYLGFDDRGCFLAALQSHQRQALPTLLGELMDRKAQAYLSAVREHLAIFPGVRELVHD
                     AAARYPLAIASGALRNEIELILEEAGLRKAFLHITSAEDVTRGKPAPEPFLHAMAALN
                     RQPSQPALTPDDCLVIEDSLPGIRAARAAGMKVLAVANTHTVQDLGEADAITHSLADT
                     RLSDLRSRLWGPAQGRL"
     gene            complement(56346..57113)
                     /locus_tag="PK063_01030"
     CDS             complement(56346..57113)
                     /locus_tag="PK063_01030"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0070064 - proline-rich region binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HMZ95644.1"
                     /translation="MVSSTGIPAIGSVWTDWRLLFASQPEPDLEFTEDDLDEAVPPPA
                     PPMNAPKRSKKGPFLWILLLLLVGGIGYVAMDPDAAMQMIQPYLDGGTETSQPVAQRP
                     PAPAPKPAPPAVQAPAAPIPAPAPAPSMAPPAVVDSVPPPPAEAPTPMPAPAPAAVVP
                     APVPAMKPASAPVRVAGPLYAEGQRVMVIADPSRPKSPMPLFADSIGTKTSTTVPAST
                     TLTILDGEYQKNGWIYSVRTQDGKKGWISERSLRLKR"
     gene            57397..57810
                     /locus_tag="PK063_01035"
     CDS             57397..57810
                     /locus_tag="PK063_01035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="secondary thiamine-phosphate synthase enzyme
                     YjbQ"
                     /protein_id="HMZ95645.1"
                     /translation="MRSYREELWFETKTRRAYLNITAQVEAAVRKSGVREGLVLVNAM
                     HITASVYINDDEAGLLQDYDTFLERLAPHDATYRHNNTGEDNGDAHIKRQLMGREVVV
                     AITDGKLDFGPWEQIFYGEFDGRRRKRVLVKVIGE"
     gene            57964..58977
                     /locus_tag="PK063_01040"
     CDS             57964..58977
                     /locus_tag="PK063_01040"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95646.1"
                     /translation="MLSWSRPDPLTRDLIHLINARRHDHGDTDAAIDTLQAFIEQGRE
                     QDLLTVLAALDEEMAEWMFDLVAEASCAVIMDGPDEEKNAYALMAALELPLQANLGQP
                     LGLKIDPVATADLLHRHLHIPAGVVVRVEPRLLTDATLEGLTLQTLNEHLASIADSQR
                     TQAIASRLYPPVENTAFLFFQLIGMPDPGLPDSLEEPERRALLEGLVTQCSELALAPD
                     TLEVPVYASYALFDAQNAVRLHRLADETAAVWRDLDPMVRARTIVHLHTQCGNGVYMP
                     VWTDLFDPELPEDHGPVWTSPDVWVFTADLPIEWPGEMLTNRLLAEGCTRFENHIVEA
                     PEN"
     gene            59030..59638
                     /locus_tag="PK063_01045"
     CDS             59030..59638
                     /locus_tag="PK063_01045"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine rich repeat-containing protein"
                     /protein_id="HMZ95647.1"
                     /translation="MAGSSRIGAVVLVTLLSCLVLGGIWGVVLFVLPQSESPPEALPV
                     SVPTPPLPVPAATQPPDRPMIDDAARPGVANAEPPVVVPQPSVPPVAEAARMPIGREV
                     KCALEMDALCPEEEGDRRACLQRKAAQMSQPCRPMLRDKLARMKENWQQLRVACEADR
                     RQFCREVPSAGGELLLQCLESHAQEVSDQCFQFLPKRGRLLN"
     gene            complement(59639..60361)
                     /locus_tag="PK063_01050"
     CDS             complement(59639..60361)
                     /locus_tag="PK063_01050"
                     /inference="COORDINATES: protein motif:HMM:NF028007.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051219 - phosphoprotein binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FHA domain-containing protein"
                     /protein_id="HMZ95648.1"
                     /translation="MSQHSIPPLLLVRSPHGGTRECEIRRTPFTIGRKPDNDLCLEDP
                     AVSAHHARIVQVQGVLFLEDLSSTNGSFVNEHPIDRRQLQDADALRFGTHRVIFREKP
                     GLAAEPIIPADMLVADKTMVVPSQAPRESPAPARKVGIVEILSGRTGQSHYPLTRQVS
                     LIGAQDDAVITLTGWFAPKTAAMISRRGEAYVVSQTESGKRILVNGRPVQREHALRHG
                     DVVEVAGITMRFVLRDERSHAA"
     gene            complement(60383..61207)
                     /locus_tag="PK063_01055"
     CDS             complement(60383..61207)
                     /locus_tag="PK063_01055"
                     /inference="COORDINATES: protein motif:HMM:NF018884.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HMZ95649.1"
                     /translation="MHAWHVTHGAASDVGLVRRLNEDRYHADPAAGIFVVCDGMGGHR
                     AGEIASSRTVETIAHHLAEAETDRSLPLIGISRPEFSSATNRLASAVRLANHRVHQEA
                     ARRTEYAGMGTTVVAVRLTGAVLSIAHVGDSRLYLIRDGAVQLLTVDHSLVQEQMQSG
                     LLAAADMARAPHRHVLTRAVGVHPLVDVELGEMPVLPDDILLLCSDGLTAGVTADVIL
                     RVSQESIDPQAMADRLIALSNAAGGTDNATVIVALVTQRPTSLWDRIYTQLVSPPA"
     gene            complement(61216..62625)
                     /locus_tag="PK063_01060"
     CDS             complement(61216..62625)
                     /locus_tag="PK063_01060"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: protein motif:HMM:NF012298.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase"
                     /protein_id="HMZ95650.1"
                     /translation="MTTSWGWIGPYFIVILLAVLVGPFLATLPLFTHTYLRPLGMNVA
                     QVVRFIADGICLLMIWSAASRARRDLKDNGKGQTFLRAILFPSASLLIVIAAFQAYEA
                     HGISVLGPPRQPLYTWLVTGGLIGSATWLTFAWVRHVDALTSMFAWRPRRRAVAEEPV
                     RAEKPDEVRAADEAIPAAPPRPTAGIAVRNGNGVPSTLGRYQVLKELGRGAMGVVYLG
                     KDPTIQRFVAIKTMRLDDIDKEEDLKEFRDRFFREAESTGRLSHPNIITVYDAGEQDG
                     LAYIAMEYLEGVLLNCYCQKSTLVPAKQALQIVATVAEALDYAHSQGVIHRDVKPPNI
                     MILKQRLVKVMDFGIAKMASASKTQSSMIVGTPRYMSPEQATGKDVDGRSDVFSLGIV
                     LFELLTGERPFDAENMPALVMRIAKSPHAPLMKYRRDLPTRVQSILDRALQKEIQNRY
                     RHAGDMAQDLRDVFQVMPR"
     gene            complement(62766..63614)
                     /locus_tag="PK063_01065"
     CDS             complement(62766..63614)
                     /locus_tag="PK063_01065"
                     /inference="COORDINATES: protein motif:HMM:NF014826.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HMZ95651.1"
                     /translation="MSRIDLHLHTTHSDGSCSTAEVMAFAKQAGLTALAITDHDIVDG
                     IPEATAIGKELGIEVVPGVEISSRLGESELHILGYFLNWTDPLLAQRLSTLRDSRHLR
                     NPKIVQRLNELGIPITYEEVRALAGTESVGRPHIARLLMEKKFVTSAKEAFDRYLANG
                     RPAFVDRELPEPAEAVRWIREAGGVPVLAHPTWVRTSAEGLRVLVRDLKAAGLGGMEV
                     HYSTHTPSQTTEYLDLARQCDLLVTGGSDFHGVTKPDIEVGIGRGQLKVSQKLLDPLR
                     KAATSS"
     gene            complement(63611..64549)
                     /gene="folB"
                     /locus_tag="PK063_01070"
     CDS             complement(63611..64549)
                     /gene="folB"
                     /locus_tag="PK063_01070"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: protein motif:HMM:TIGR00526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004150 - dihydroneopterin aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006760 - folic acid-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HMZ95652.1"
                     /translation="MAERIVIERLEFYGRCGVTEEERRKPQLIVVDLELDAAVEAAAV
                     SDRLSETIDYAQVAERIVALSTSLTCQLLETLAEQLVGMLFAEFPADRVRIWIRKVHA
                     PLAMVAGSVGIRFERTRAAHQSTHQALSAAPFLIQQLARLPKGHILDVAAGRGRNALY
                     LLAQGSQVEAIDRDTDALSALEAAAGTQRLSGLTTRVLNLEASADHPPSLGHECYDAI
                     VVFFYLHRPLFPVIIDALKPNGILLYETFTIDNYFRHQHPRRWEFCLAQNELLRLTSP
                     LRVLHYDEGEHDGGHGSGPCYTARLVAQKTGPETSP"
     gene            complement(64608..65078)
                     /locus_tag="PK063_01075"
     CDS             complement(64608..65078)
                     /locus_tag="PK063_01075"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95653.1"
                     /translation="MFLPARVFTSKNRRTSLQSIPRRFNGQSIDEQIRAVQSAWVDVL
                     TLPLCLTVLAFYEWWRWLFSIPSNPLLLTVVAAVAIHATRRRRKAYKAELKQLHLNRT
                     PQPTVSDVTEFLYRGARRMVQDFTAKCSPATIVASARRFASPANWLTKRLFARS"
     assembly_gap    65197..65296
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(65328..65846)
                     /locus_tag="PK063_01080"
     CDS             complement(65328..65846)
                     /locus_tag="PK063_01080"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95654.1"
                     /translation="MTMRHFVHIAAIIGVLAVSGSTEAAELAGAWKGVLSSPDGSRAE
                     VQIDFSPQGLPLYSYTNNKGVTRQVELSHVGQTIEYVPPGGGVQRMAVKRFEQGPGRV
                     SISIIGSFERASQGYMDQRQEAALFEYTLVPEGMKMRVTTRTASHFGDKDLIVGGDPS
                     SVVAEGVLHRLH"
     gene            complement(65891..66802)
                     /locus_tag="PK063_01085"
     CDS             complement(65891..66802)
                     /locus_tag="PK063_01085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="caspase family protein"
                     /protein_id="HMZ95655.1"
                     /translation="MAKTTTASAAKPKALSLHIGLNAVSPAAYGGWSGELAACEFDAK
                     DMAAIAKSQGMKSTVLLTKQGTRAKMLAAMRKAAKQLKQGDLFFLTYSGHGGQVPDVT
                     GEEIDKQDETWCLYDGQLIDDELYFELSRFAAGVRILVLSDSCHSGTVTRAVPPPIDR
                     TKVTGRSKMMPPAVAIRTYREHQAFYNKLQHDVAKAAGKAGTTDPDSVLAQLAVSPRL
                     TAIAKEFHPAVILISGCQDNQTSMDGDHNGAFTEQVLKAWNHGNYRGNYAKFHAAVKA
                     GLPASQSPNLFTLGAAGRFLRQQPFKV"
     gene            complement(66981..67136)
                     /locus_tag="PK063_01090"
     CDS             complement(66981..67136)
                     /locus_tag="PK063_01090"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95656.1"
                     /translation="MVVKQGYRLIVVDKDGVLVSEFQLTAQALAAPETFVAAIKESIE
                     EIEEEDT"
     gene            67326..68348
                     /locus_tag="PK063_01095"
     CDS             67326..68348
                     /locus_tag="PK063_01095"
                     /inference="COORDINATES: protein motif:HMM:NF016190.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HMZ95657.1"
                     /translation="MHTTKLIAAFLVLVLVGVPTISFAKARGGSGGGFSSGSRSGSSG
                     SMGSRGSRTYQDNGAKPIEQSTTARPSATPPPSMAGNPSTASRPAPAAQPSWFQRNPL
                     LAGIVGGLAGTWLGHMIFGATDTSARTTEGGEGEQAAAGAGSSGMLLLLMVMGGGALW
                     WYMRSRRTPAPNFSGLSRTSVASGSLLAESSRAGFGAAAVEEEMTSTDKAAFQQALID
                     IQTAWSHQDLAGLRRLVTPEMLDYFSTGLAEQASEGVANRVEDVVLGQAEVRESWSEG
                     ATQYATVSLCWRAKDYTISLAKQPGEQGYIVEGNAELPIETTEVWTFMRFGAGKWLLS
                     AIQQVS"
     gene            complement(68550..68861)
                     /locus_tag="PK063_01100"
     CDS             complement(68550..68861)
                     /locus_tag="PK063_01100"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95658.1"
                     /translation="MPISRRPELEKDNPVAPQIYVGPRRKRSLARKTSSELQAPSDEM
                     ATRLQRLVEAAEQFVHSMPPVQETDQERHALLEAISQAQGCLPIEDTAATRLRQASHT
                     R"
     gene            69628..70128
                     /gene="moaC"
                     /locus_tag="PK063_01105"
     CDS             69628..70128
                     /gene="moaC"
                     /locus_tag="PK063_01105"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018465116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HMZ95659.1"
                     /translation="MADFTHFNESGRARMVDVGAKASTERLATAQAIVFLQPETLEKI
                     QQGKIAKGDVLSVAQVAGVMGAKKTPDLIPMCHPILLTSVDISFQEIAQRDREGRCSI
                     VISATAKTTGPTGVEMEAMTAASVAALTIYDMCKAVDRGMSFGDICLLTKSGGKSGTY
                     QRPVPV"
     gene            70138..70401
                     /locus_tag="PK063_01110"
     CDS             70138..70401
                     /locus_tag="PK063_01110"
                     /inference="COORDINATES: protein motif:HMM:NF014636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoaD/ThiS family protein"
                     /protein_id="HMZ95660.1"
                     /translation="MVTVRLFGMTKMLAGNQGALSLALPEGRRVKDLVSVIEAAYPKI
                     GELLHKKKVLVSVNQDIAHEDLEVRDGDEIALLPPFAGGSAGC"
     gene            70550..71023
                     /locus_tag="PK063_01115"
     CDS             70550..71023
                     /locus_tag="PK063_01115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein MoaE"
                     /protein_id="HMZ95661.1"
                     /translation="MSLEQVTKADQPVTGDEAMLVRVQREDFSIDEELCRVRARSKRI
                     GGIAIFLGTARDRSKGKDVDGITFEHYEGMAQKKLREIRERALKDFGIIELSILHRYG
                     EIGIGDNIVLIIAGAEHRAEAFQACKWAIDELKQITPIWKLEHTPEGEVWVEEHP"
     gene            71071..72132
                     /gene="moaA"
                     /locus_tag="PK063_01120"
     CDS             71071..72132
                     /gene="moaA"
                     /locus_tag="PK063_01120"
                     /EC_number="4.1.99.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HMZ95662.1"
                     /translation="MDHTPDTPVPTIYDRLGRPLRSLRLSVTDRCNLRCKYCMPEDDY
                     AWLPRDTILTFEEMAELTAVFTELGVDKVRLTGGEPLLRRDLPRFVRQLSENRRITEI
                     ALTSNGVLMADQAADLSFAGLNRVTISLDTLRADRFRTLTKRDLHHQVFDGIKAVVQA
                     GFPSLKFDTVVIKGYNDDELIDLIEYGKTVGGEVRFIEYMDVGGATDWSMKQVLSKAE
                     MLELVGRHYGGVKPVVENSAAPAERFVLPDGTIFGIIPSTTTPFCRACDRSRLTADGM
                     WYLCLYAKDGLDLRAPLRQGRTRDELKALIIAAWEGRADRGAEERKALEVLGLREQRL
                     IEINRLREDPHLEMHARGG"
     gene            72193..72900
                     /locus_tag="PK063_01125"
     CDS             72193..72900
                     /locus_tag="PK063_01125"
                     /inference="COORDINATES: protein motif:HMM:NF015763.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95663.1"
                     /translation="MFDPHTLTILSLGFVLGLRHALDADHLAALSTVLAERPTVQAST
                     AIGFFWGLGHTLMLLCVGTLLLALNLTIPESMANLFEFAVGGMLVALGLSLARRVYRE
                     QWHVHTHEHGGRPHVHLHSHHLQADHTHGHWYQGSLRPLAIGMAHGLAGSAALMLVVL
                     STVTGMAQGIGYIVVFGVGSILGMVGVGAVLSLPVIYSVTVGPRAYWMVQGLTCLASI
                     GLGVVMMVRIGLAGGWS"
     gene            73100..73888
                     /locus_tag="PK063_01130"
     CDS             73100..73888
                     /locus_tag="PK063_01130"
                     /EC_number="3.1.4.17"
                     /inference="COORDINATES: protein motif:HMM:NF024874.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004114 - 3',5'-cyclic-nucleotide
                     phosphodiesterase activity [Evidence IEA];
                     GO_function: GO:0008081 - phosphoric diester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3',5'-cyclic-nucleotide phosphodiesterase"
                     /protein_id="HMZ95664.1"
                     /translation="MNVRVLGCHGSGQLVPGENGPVQCGTCGFLINEELLVDAGTVGS
                     RLYLEEQRRIRLVLLTHLHFDHIRELPTLADNLVGEIEEPVVIAAIPEVLDGLRRHIF
                     NGTVYPDFFRLPDPVKPVFVSRELLPGQETLLCGLGVTPIPVNHVVPTVGFLIREQRR
                     TVLFSGDTYQTDALWQAAGDVDALQAAFIECSFSDEMAELARVAKHLTPALLAEEFAK
                     LAKPEVPVYAYHLKPRFRAQIRQELGGLGIRHLTALEEGQTLVL"
     gene            73899..74735
                     /gene="accD"
                     /locus_tag="PK063_01135"
     CDS             73899..74735
                     /gene="accD"
                     /locus_tag="PK063_01135"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HMZ95665.1"
                     /translation="MAWFKKGKTEEAEPPKRSKTAEGMWLKCNHCREIVYRKEVDRNN
                     KVCPKCDYHFPISVIERINLLVDLGTFKEWDPELEPQDPLQFQDTRSYKDRIKAQQEK
                     TGRKDAMVIGQGVINGRKVALCVFDFGFMGGSMGSVVGEKICRAVDRALEARMPLILV
                     TASGGARMQEGILSLMQMAKTSAAVAKLGEAKLPFISILADPTFGGVTASIAMLGDVI
                     IAEPKALIGFAGPRVIEQTIKQQLPDQFQRAEFLLDHGMIDMIVERKQLKEAVSTLVG
                     HF"
     gene            74816..76198
                     /locus_tag="PK063_01140"
     CDS             74816..76198
                     /locus_tag="PK063_01140"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: protein motif:HMM:TIGR01499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HMZ95666.1"
                     /translation="MFATAFPDDHFRILVSFDVNMQCESPVAPMTYPATVQFLYGLQL
                     HGIKLGLETIRTLLARVGDPHRQYPVLHIGGTNGKGSTAAMTASILQVSGHRVGLYTS
                     PHLIDFRERIRVNGEMIPESRVIHGVELLRAASAPDLAPTFFEFTTALAFHHFAECQV
                     DVVVLEVGLGGRFDATNVVEPLAAAITTIGLDHEAYLGSTIEAIAMEKAGIIKPGVPV
                     VLGRIGEPGSRVIEERASTVGAPVLRLDRDFRCEGSSPADCRYTGFGLRLEHLSCPLQ
                     GRFQIDNVACSLALIELAHERGVTVTETSVRAGLQQVAWEGRLEIVGQEPTVMVDGAH
                     NPAAAAVLAEYLSEWKRVSPAARLCLIVGMMRDKHPREFLAPLLPLIDTLILTQADLP
                     RAATGSELRLLLEHDAPFAQVATTPSDALAMAKHSAAASDVVCVTGSLMLVGEIKALL
                     RGDSLSPVRG"
     gene            76200..>77158
                     /locus_tag="PK063_01145"
     CDS             76200..>77158
                     /locus_tag="PK063_01145"
                     /inference="COORDINATES: protein motif:HMM:NF040057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative LPS assembly protein LptD"
                     /protein_id="HMZ95667.1"
                     /translation="MGRDGYSVSTWQRLISHFPCILSISILFGLFPLFAPSAWGESTV
                     TTVSPTNQPLTVTAERIDHLQEREVYEADGSVVVTQGNLRLTADHVTINALPGTLTAT
                     GRVHFWDASSDLKSERLELNVNTEAGIVANGSMFIRPSNSFFTGRSIRRLSEDHYRIK
                     EGTFTNCDAKEGEVPAWRFTFEDLDVNAGESIGMKRAWLCANDTPIIPVPTLTYPLSN
                     RHSGFLIPTPGYDNRFGLHYQQGYFWAINPSQDLTIAPSYYNNLGYGSDFTYRYYLDR
                     RSSGQWFASFLQQTKLPNVSGVDQVSSDERRLRGLISGQHVQQV"
     assembly_gap    77159..77258
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <77259..78841
                     /gene="lptD"
                     /locus_tag="PK063_01150"
     CDS             <77259..78841
                     /gene="lptD"
                     /locus_tag="PK063_01150"
                     /inference="COORDINATES: protein motif:HMM:NF016348.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_process: GO:0010033 - response to organic substance
                     [Evidence IEA];
                     GO_process: GO:0061024 - membrane organization [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="LPS assembly protein LptD"
                     /protein_id="HMZ95668.1"
                     /translation="SDERRLRGLISGQHVQQVTDTLLVRGQASFVSDRQYLQQLSNSG
                     TQRASPSGESTLLATQRLPYGSAYFLGQYLQPLNSGGPDTFQRLPEVGYVLPNTSPFG
                     MPVLLNLDTNFVNFYREQGFAVNRMDFMPGVTTEVMDVGHVIGLTPHVKFKEVYYTRG
                     IQEASPLHRETFWAAMDATSKLSRRYTGGEGGSFLHTIEPSVIYEYVPGSDQSKIAQI
                     DQIDDIPKKNLLTYALRTKFLEQQLNGQSFNWLDLTVAQSYHVGAVQTRAREFTPGVL
                     PFLGSLTQPLQPATVDVQGRKMSDVWMRAVIGNTAPEFFRPPAINEALGKNVTGGQML
                     PPTNSYLQVDAFLDPYRGTFSQWNTDLRVQQSNYWYVEVGQRFSHDGNRVRRGDIWNP
                     VSFNEVYAPTKEIQFATAGGGFRTPWGWTIGAKGYYDVKGGRSPEFDVVALYQNPCKC
                     WSLGLYYLQFPDRQSYSFMFSMTGIGWTENFGTIVARTILGPLLVGDRGLPWAAPGGP
                     YGRVQNALPVQSMPMGRY"
     gene            78884..79450
                     /locus_tag="PK063_01155"
     CDS             78884..79450
                     /locus_tag="PK063_01155"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95669.1"
                     /translation="MIETKRAAGIRLNRRTVLTTCLLMLAIAVQEIYPSGLSATEHMA
                     HLERAAVFLKAGDYRQALEACQAEVKDRPSARSYLYLTYAYHALDGYLQYLANTDQWV
                     RVEHLYVNLSTGRVEDLLDPPDVLARIAKEVIQQAAQRQADVTAALAGRLDETLVKQL
                     WQQQTAWRQARPDDWWSAAPPQWQWAAP"
     gene            79553..79900
                     /gene="trxA"
                     /locus_tag="PK063_01160"
     CDS             79553..79900
                     /gene="trxA"
                     /locus_tag="PK063_01160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HMZ95670.1"
                     /translation="MAGDALKATDATWDEDVMKASELVMVDFWAVWCGPCQMVAPIVD
                     ELATEYAGKVKVRKLNTDENPEIAGRYQVMSIPTILFFKNGQAVERLVGARPKRQFKE
                     IIDTLLAQHSGAA"
     gene            79919..81604
                     /gene="recN"
                     /locus_tag="PK063_01165"
     CDS             79919..81604
                     /gene="recN"
                     /locus_tag="PK063_01165"
                     /inference="COORDINATES: protein motif:HMM:NF008121.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HMZ95671.1"
                     /translation="MLTELRISNFGVIEQLAVTFGAGFIVFTGETGAGKSLLIDAVTL
                     LVGGRASAEHIRAQAEEAELEAAFHLPPEHPLLALLRNKGFARSGETDILIRRIISRT
                     GRNRTYLNGNLCPVHLLEELGGALVDVHGQHEQQSLLSPSAQMDALDAFGGFQPLRQE
                     YQHAYRDWQDRVGDLETLTAQIAQRREREDLLRFQFQEMTDAGIEAGEDARLEQERPR
                     LMHSQQLGELSDQLHELLYAGDQGVLSLLAGARKLLAKMESLDATTVEWIKTMDEAVV
                     PLKDLADQVRRYRDHVEANPSRLLEIEQRLDRLHRLAKKYGGSLDAMLAWQDSLRAQL
                     AELDHAETHLQERTRAVEQAVLSLRDVADRLSRKRLDAAKKITAQVMKELGGLRMERT
                     RFSVEVSRLSGDAPYGQTGQDTVEFMFSANPGEPLKPLAKVASGGELSRVMLALKTIL
                     AESDQVPVLIFDEVDAGVGGAVAEVMGVRLRSLSRHHQVLCVTHLPQVGSQAHAHYLV
                     EKWVRQNRTMTQVRLLDLDEREEEVARMLAGVTVTKKARAAAAEMIASAKDRQ"
     gene            complement(81612..82754)
                     /locus_tag="PK063_01170"
     CDS             complement(81612..82754)
                     /locus_tag="PK063_01170"
                     /inference="COORDINATES: protein motif:HMM:NF014069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ95672.1"
                     /translation="MGTQASTEQISIKPSVLVVDDETGPRDALKVILRPFFTIHSADN
                     AKSALRVLKDQHIDLITLDQKLPDRQGIDLLQDIKQDYADIEVIIITGYGSLKSAMEG
                     IRHGAAGYLLKPFNVTELITLINQTLEKKQRLDYLRSFLKTSTALWGTEQEAAEAWKD
                     LQSKYFAIGNSSTDATGTAADVTALIPLLSDLLEAKDRQLLNHCSRVSFYASLLANQL
                     TLPLPDQKALALGAFLHDIGKISLSNYKYSADDDESLKTNTHGKECFETGARMLLPLG
                     FQAEVGQIVAYHQERFDGVGNPHGLEGEGIPLLARIVAIAQAFDNLTVDMPGHQPTSI
                     DEAIRQILLQADTYFDPKLTELFAHVVRECKSSLPALAIAKTSPTN"
     gene            complement(82941..84356)
                     /locus_tag="PK063_01175"
     CDS             complement(82941..84356)
                     /locus_tag="PK063_01175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ95673.1"
                     /translation="MKKRVLLVDDEPRVRASLRTVLEPTYEIFEAADAAEGLRSFKHD
                     APDLVLLDVILPGADGLSALQTMRTENRAVPVIMLTGTKAVKTAVDAMKLGAADYLSK
                     PFDVEELQIVIERTLGKQELEQEVRQLRAQVVQRYAFHNLIGKSPAMQEIYAKIEQVA
                     DSRTTVLVTGESGTGKELVAKAIHYNSARRERPFVALNCAALPETLIESELFGHEKGS
                     FTDATARRVGQFELAHTGTLFLDEIGDLSPATQAKLLRVLQEREFTRVGGVQSIKVDV
                     RIVAATNKNLDEMVRKNQFREDLYYRINVIALYLPPLRERGEDIALLAKHFLSKRIEE
                     EKRPSQEFTKDALELISHYPWPGNVREMENIIEQAFIWSKGSTVITPEHLPNILRTDT
                     RSSSLRDDTLAGRLSLEKAVMEFEREIILDALKRTTYVQTHAATMLGISRRMLKYRMD
                     TLGISRPDSGGGNAEASLPQE"
     gene            complement(84358..85512)
                     /locus_tag="PK063_01180"
     CDS             complement(84358..85512)
                     /locus_tag="PK063_01180"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ95674.1"
                     /translation="MTALSQYTRLPEVALWIRESTGERYRLLASYGHNHPSSLPSTLT
                     GDHPLVAGLSAKPYVCHGSENPSKPLGLAMATARASLCLGLRTKGRLLGICILGPLDT
                     KAQVGEELLAIVDAITHIAGNSLDHYLTQDDLRRSSTLMRRTDRLRSLEIMAGGFAHE
                     IRNPLTSIKTFVQLAPQRQQDPVFIKEFSKLAIEDIHRIERLLHEILDYASYMTPRPT
                     EVDLNDLVASCIGFISSSAAHRGIQVQTHLSPQLPLLLLDRQQIKQVLLNLLLNALDA
                     MPNGNGIIRVHTRLLSEAGRPPWVQLQVEDEGCGIAPDHLEHIFDPFFSTKHSNSASE
                     GAGLGLTTAHQIVREHGGTLIVESRLGAGSTFSVNLPVPDSAPTVSAARE"
     gene            complement(85748..89929)
                     /locus_tag="PK063_01185"
     CDS             complement(85748..89929)
                     /locus_tag="PK063_01185"
                     /inference="COORDINATES: protein motif:HMM:NF024880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HMZ95675.1"
                     /translation="MSLPEPSLHILLINENADEIKLVTTSLRSFFVGCRIEAGYSSED
                     ALAFTRQGDWQIILIDQDLSPERGLDLLARLRRNAPYAAILLQTNESDSHTAVQALQH
                     GADFLLFKRSPGFLTELLFSVQEALEKRDLQMKLDHTFQRHLRVIETLSDLLYELDAD
                     GRFVYVSPTVTAMLGYTAEELAGRHYSLLLPPQQEPTARFRLNERRAGSRSTRRVELT
                     LYRKALPEAPSVPIIVEVTAKGLFDSTNRYLGTVGLLRDLSQQKAQQNRLAELESRLQ
                     ETDRQLTLSREAARVSRQLQQPLTSLLQDSQRLLTSIQHSRFEQHVETMVAQASQASQ
                     LGHQLAEAIHAPPTELILLDLNEVLQTVAQTTHGETEDSQFLLTTQFAANLPLILGSR
                     ADLEDLTHILLSYACRSTPDNTRPSLTLHTAVLAVETSGSPGQEVASLSRPLRTYASF
                     TIRGSASSLRLPPDSQSGHDRSAVSLFQAHRIVQVHRGAIEVEHTPESGLAITVRIPA
                     SEDFSLTGTPATTISPPPTDIHKPGRDTSQRPERRRSERKPFSLPVQLSIGGTTLRGL
                     LRNMSTEGALLTIRGMESSIHLQPAYVVIKTPVSFLELQGVVHERPSASTELSLPAIK
                     DFVISFALAVEHERNVLRSLLEGLQEGSPQITFEGLILPLPIAQTIQHRNLLPLREMP
                     EDRREAARLSVSCPVYITGSDAASSRPFGKIINLNLNGACIELPTEVVLTEHSRVIHL
                     NPLESITMVPGTSQAPEAEQPLTAQILWNDSAERRLKLRLAATGHHLQQIGIRFDTLS
                     PAQEQRLRSIMEAEFRAEQHLAETPSDAPVLTVSHTVRNREGYTIALRHDFPTGGGSE
                     HDPLVLLCPGYGTTQHAYVALAYMLAGRGFHVVRYDHSRHIGLSDGDPSQTTFTSLED
                     DLDTVLTFVQEHWPERPLTILAPDLPARIALRRQDWHRRIRRLLLLNPTLDLGQCLQT
                     LHHRDLLQEHLNGTCLGLGNLLGIPLDIDHFLADAVAAQYTDVRVLHNELAHCETEVV
                     VLTGGQDGPDCSIPPPPQPLVNDLLSRLGVKGRKVLLPSSTLTSGPQPPSTLRASWQQ
                     VSHLCQAGQALHEPGRVMLPSLLLATSTRARFERDQLRHKHAIGTTSNERLWTAHTEL
                     TRALDELPAHWQSIDQLYQLLQPLDGNVALLDIGCGMHSFARLLLLNLSYRLRAQTWH
                     HNHPLRYVGLDFSSASLHAARASTKEALQHLDELFSGRISAPTPVTQQWILGRSADAL
                     PFADCSFDRVVANFSLSFVRSPVHSLREFFRVLRPGGKLILKAFTPATDLARLYRPAL
                     HEIGIDAFSGAPRLALHRMGQCAVALRTGQLHTFEEESLTTLIARFTPLTPRLVRTLA
                     GQILLAAAEKPDSSS"
     gene            complement(90309..91310)
                     /locus_tag="PK063_01190"
     CDS             complement(90309..91310)
                     /locus_tag="PK063_01190"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95676.1"
                     /translation="MNRALLLVVMFLGVTSLAYADGGHDHHAIPTMPSLGETKLTIDE
                     QTVTLTFGPVDLPTGHDGDLASSMPKKVFQLPEDTYMIGYKSEVFTKDGKPLPKNYLH
                     HILMLNNDKPSVSCDGEPLFFAGAGLEMTEARFPDGYGVKLGKGQNLMSVVAFYHKAP
                     PTKDVMARFTMYVAPKGAKVQEMDVYQVGVNIVCYSKFAQRGPDQTDEGIEIKSGVSV
                     LSAPLKFNMDGCVKFAYPHGHDELLMVALENKTSKETLLRTVPEVDADGTFRDFRPHQ
                     VYRDSKGFSVTKQDDYEMVMVHHHLLQNPNIQHGMGNYLLYMTPGACQQSSTTAAAH"
     gene            complement(91386..92291)
                     /locus_tag="PK063_01195"
     CDS             complement(91386..92291)
                     /locus_tag="PK063_01195"
                     /inference="COORDINATES: protein motif:HMM:NF024865.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HMZ95677.1"
                     /translation="MESHYFRPLSLRVRTWLLLGPLLGMLYLPTARAGEPHDAETTLR
                     RLVQANAERDLATMSKYMSHDVDAIGYTIDGRKYIGWSDLAADMRSEFDSVVKLEIPI
                     TDLRMWNNKDVAWFAMELDYIRYSDPADLAQRMVLHLRETGVLEQRNGRWILVAWHES
                     TRHHDSGTEQTAANGAALLHRASDAQPAVPNGVDLSGEWEVTEIEDNKKYVATLNAQG
                     TGPYTWQGGQFSTTSFNDRRWQGTWKQTGNDREGAFEVVLSEDGTEAKGIWWYVRVGT
                     RDNIPPRQHGGSYLWKRLTPPPTAP"
     gene            complement(92378..93184)
                     /locus_tag="PK063_01200"
     CDS             complement(92378..93184)
                     /locus_tag="PK063_01200"
                     /inference="COORDINATES: protein motif:HMM:NF018884.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase 2C domain-containing
                     protein"
                     /protein_id="HMZ95678.1"
                     /translation="MALAQGKWDWTGYGQTDRGLVRSTNQDAFLVDNRRRLWAVADGM
                     GGHPGGDVASRIVMDTLADFSPSLIRNSDNLDEDHTEQQSFRLTTMAEQAHDAVRAYA
                     DRHPSVYGMGTTLVMAHLMPLPAPRLLVLNVGDSRAYLVRAGRITQLTRDHTLIDDYV
                     REGRLTPEQAARHPDRHVLTRAIGLEPVLQIDLFPVDVFVGDVLLLCSDGLTKMLPDE
                     HILKIAQSHRDSPSLTTQALIQAAIDTGGIDNITVVACAMTSLPDQGNIH"
     gene            complement(93186..93959)
                     /locus_tag="PK063_01205"
     CDS             complement(93186..93959)
                     /locus_tag="PK063_01205"
                     /inference="COORDINATES: protein motif:HMM:NF024873.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H-like domain-containing protein"
                     /protein_id="HMZ95679.1"
                     /translation="MLTSTFVHLKGIGPSTERRLWESGIADWATFRREAHLTGIAPAR
                     KAAYDAELALAQDHLDLHNPRYFADCLHTRDHWRLFQTFGARALYLDIETTGLSAREG
                     QVTIVGLHRQGRMRTLIHGQDLTLEAIQEELDQADLLITFFGTVFDIPYLQTCFHGLR
                     VAIPHFDLCFAARRVGLQGGLKSIERELDIARESDLLQLDGLEAVRLWHHYRAGHDEA
                     LDQLVRYNAADTQNLEPLAACLYERLVLRYGPQSLGLVG"
     gene            94076..94486
                     /locus_tag="PK063_01210"
     CDS             94076..94486
                     /locus_tag="PK063_01210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclophilin-like fold protein"
                     /protein_id="HMZ95680.1"
                     /translation="MTTNGTMKRIRIKVGGLQLEAELKGTRTAEELYRALPAEGPLNV
                     WGEEFYFKIPGVKDHRETATTQVKIGDVAFWGAGQVLAIFFGRTPMSMGADPVPADRV
                     NVVGRVLGDAATLRQAMNASMIRVERIEPAQPVG"
     gene            94522..95112
                     /locus_tag="PK063_01215"
                     /pseudo
     CDS             94522..95112
                     /locus_tag="PK063_01215"
                     /inference="COORDINATES: protein motif:HMM:NF016271.2"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF507 family protein"
     gene            95147..95587
                     /locus_tag="PK063_01220"
     CDS             95147..95587
                     /locus_tag="PK063_01220"
                     /inference="COORDINATES: protein motif:HMM:NF025910.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ95681.1"
                     /translation="MRVSRWIALVVVVLSCSACAHEKPKPLVPLELAYGAKADANALN
                     NQGRQAFLAGQMAEAKDFFGQVIKIAPDSGQAHYNYGLTLNALGQTDQARQEFIEAAN
                     LAPGDKVIWDSPALRPFGNPEVPKGPAREHPYGTSRPTIGSGPR"
     gene            95622..96089
                     /gene="bcp"
                     /locus_tag="PK063_01225"
     CDS             95622..96089
                     /gene="bcp"
                     /locus_tag="PK063_01225"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016209 - antioxidant activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HMZ95682.1"
                     /translation="MASGVEVGAKAPEFSLPDQDGNLVTLKSLKGKQVVLYFYPKDDT
                     SGCTKEACDFRDSLAAIKKTGAVVIGVSKDGKTSHQKFIAKYGLPFALLSDEDTAVST
                     AYDVYKEKSMYGRKYMGIERSTFVIDATGRIKASFRKVKVPGHVEEVLAALKA"
     gene            96193..96381
                     /locus_tag="PK063_01230"
     CDS             96193..96381
                     /locus_tag="PK063_01230"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95683.1"
                     /translation="MPGLGHLYIGEKRGGPLLAAGLLLIILWTNWFAFALVPLLGLVL
                     FSMGDTYLTVSRDRGLFS"
     gene            96421..97287
                     /locus_tag="PK063_01235"
     CDS             96421..97287
                     /locus_tag="PK063_01235"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95684.1"
                     /translation="MAEVVGLGLRIFGVLLCAALALATTGEAAGKVSGTLILHDALTL
                     PNHSVRIEAQVAVTAAGPPLSGLMLHLQIDGKDVATAKTNEGGRAAFDYLAKMRGTNV
                     ISVSIDPDAPVAAEKVDATLCVWERRRPIVVVELDALIQQSPAPATPAASPGIGVTDD
                     TVPTPVPEAAEELSRLTQYYYNVVYVSNNEQGPMGNVSSGQVRRWLEAHQFPVGFVAT
                     PTSGGLNATLDALKHDGWTTMKSGIGRTRGFADMLLQHRMEVVVVPELPKGELPRKAK
                     AAKDWKEVRKKL"
     gene            97540..98319
                     /locus_tag="PK063_01240"
     CDS             97540..98319
                     /locus_tag="PK063_01240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase"
                     /protein_id="HMZ95685.1"
                     /translation="MLLEGKKGLIIGVANKHSIAWAIAQAAAREGAQMLFSYQNERLR
                     ENVEELVQTLPGASACVCDVGDDSQIAAMMKEAAEKLGRLDFVVHSLAFAPREELTGE
                     FVNTTRQGFATALDVSAYSLVAVTRAAMPLMTDGGSVVTLTYLGSERVVPHYNVMGVA
                     KAALEATVRYLAHDLGPKNIRVNAVSAGPIKTLAARGVSGISKMVDHHRAFAPLRRAT
                     EQGEVGDTALFLVSPLGRGITGEVIYVDGGYHILGSLASVD"
     gene            98402..99280
                     /locus_tag="PK063_01245"
     CDS             98402..99280
                     /locus_tag="PK063_01245"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95686.1"
                     /translation="MISPPILFFCLFTLVMAGAPPPALSAQLTAREEDGLIGTVQSVE
                     TIDSLVSQTDYYDPQGRILERIQGGKDTSHGLWPLRFTYVYDKEGRRIAEMIRDAQGE
                     LVKETRAVYDAQGNRSAELSAWGDGTFENVSLYDYDELRRLRRGLHYNAVHVVNRNLY
                     SYDGGGRLLQERFERNYRYDADGHQMVTTDRFDVGHDVAIIYNDRGQVQQKTVSDLRG
                     RRQGHSEFRYDERGSQIEERSYDAAGRLMDRKTYRYEYDTVGNWITETFQWWELRDGE
                     PRIKQSHVRERRITYH"
     gene            99397..100866
                     /locus_tag="PK063_01250"
     CDS             99397..100866
                     /locus_tag="PK063_01250"
                     /inference="COORDINATES: protein motif:HMM:NF040048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6298 domain-containing protein"
                     /protein_id="HMZ95687.1"
                     /translation="MVRYSNLWQCLVTVLLLCGAGQVECWAGDTPHASHAHGPLRQSP
                     DNPRYFADADNRIVYLTGSHTWENFQDVTQVFDYPAYLDRLTALHHNFMRLWVTESIH
                     SDGGWLMNPPPNEKDIAPLPYLRTGPGLALDGGPRLDLSRFNPAYFERLRARVKDAGQ
                     RGIYVSVMFFQGFSVVTPGGWKAHPLNGQNNVNGIDGDANGDELGLEVHRSPGVPVLQ
                     IQEAYVRHVLETLHDLDNVLYEVVNEATPESVSWQYHFISFIKRYERERGFMAHPVGM
                     TFFQLGEFGGGDNRTLFESEADWISPGGYTKYARNPPATDGRQVQVLDTDHIHGIGGD
                     QQYVWESFMRGYNPIYMDPFDAVHELTIGEPVLNEPQHERARVAMGQTRRWADRINLK
                     RVTPQSELASTGYCLADRGREYLIYIPASDSVAESGAEKPTRPVTVNLTGASGVFTAE
                     WMELETGRTKQADSLIGGSERMLTVPFPGSGLLYLRKSG"
     gene            101038..101415
                     /locus_tag="PK063_01255"
     CDS             101038..101415
                     /locus_tag="PK063_01255"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95688.1"
                     /translation="MRKLTPLHGDFLAYCVDDWTGLWLLVKRIKPLHSSTDADKIQAH
                     ALEIIRDLIEAGYIMAGDVDFGLGKFRQWNLSVDKIIGRIEQEWIELGRDPTICEIVW
                     FVSTTEGDYAFASGQFPETPSTE"
     gene            complement(101475..102572)
                     /locus_tag="PK063_01260"
     CDS             complement(101475..102572)
                     /locus_tag="PK063_01260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ95689.1"
                     /translation="MKIEVRGLTKKFGSGTAVGNVSFVVHEGELLGLLGPSGSGKTTV
                     LRLIAGLEVPTSGDIFIDGKRVNDLTVQERNIGFVFQHYALFKHLTVFDNIAFGLKIK
                     KWNRQDIEQRVLELLSLMSLDGLGSRYPHQLSGGQRQRVAIARALAPRPSVLLMDEPF
                     GAVDAKVRQELREWLIRLHTDLNVTSLFVTHDQEEAMEVSGRIIVFSKGKLEQAGSPA
                     DVYEEPATEFVARFIGSMNIVEGIVRRNQVQVGSLEFPAPGFSDGQKLQVGFRPYYVK
                     VAEDATRYRQQAKLRHIYFLGVAYRLEIETADGLILRSRMNKEEFRRCNFTVGQAVSF
                     AVTHFRILPQEGAEASSEAKPGSPITGPLTP"
     gene            complement(102577..103386)
                     /locus_tag="PK063_01265"
     CDS             complement(102577..103386)
                     /locus_tag="PK063_01265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015419 - ABC-type sulfate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008272 - sulfate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate ABC transporter permease subunit"
                     /protein_id="HMZ95690.1"
                     /translation="MRWLLIGIVWLYFLVLLVGPILYMASQSFSEGLAAFWTEISRPE
                     AVHGFTLTAEITLIVLVLNLIFGTLTALVLARQQFWGRSLVSGVIDLPFAVSPVIAGF
                     MLILLFGPDTMLGALFGQAHIKILFALPAMILATLFVTFPFMVRELTPLLQTLGTEEE
                     EAARTLGAGEWQVFLKVTLPALRWGLVYGATLTVARAIGEFGAVLVVSGNILLLTQTA
                     TLHIYQSYVDFNYVAANAVALTLLAVSFAILTVLEIAKARAETTVAEAGAQ"
     gene            complement(103435..104316)
                     /gene="cysT"
                     /locus_tag="PK063_01270"
     CDS             complement(103435..104316)
                     /gene="cysT"
                     /locus_tag="PK063_01270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015419 - ABC-type sulfate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008272 - sulfate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate ABC transporter permease subunit CysT"
                     /protein_id="HMZ95691.1"
                     /translation="MTSHMLLRVALRSAAVGYVLLLIFLPLATLTQQSIASGWDRFIQ
                     DLSAPQAAAALWLTIETSAIATAINAVFGTLSALVLVRYEFPGRWLLNALVDLPFAIP
                     TLVAGLMIAAIYGPTSVLGTWLQQGGLTVLYNQPGIILAMLFVTMPFTIRSLQPVLMG
                     LERDQEEAAFTLGASPWTTFWKVTVPSVLPGLLTGVFLTFVRALGEFGSIVIVAGNIP
                     MKTQVASVYVYGEIESYNPQAATSVSVLILLISFVVLLLLERLTRRPGERLPKLFRWA
                     NRHDQPGRDAAAATAAH"
     gene            complement(104578..105642)
                     /locus_tag="PK063_01275"
     CDS             complement(104578..105642)
                     /locus_tag="PK063_01275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009897 - external side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015419 - ABC-type sulfate transporter
                     activity [Evidence IEA];
                     GO_function: GO:0043199 - sulfate binding [Evidence IEA];
                     GO_process: GO:0008272 - sulfate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate ABC transporter substrate-binding
                     protein"
                     /protein_id="HMZ95692.1"
                     /translation="MRTITHTFSTLMLSVIASWGLFTFPVAPSHAAETRDLILAAYSV
                     PKEAYERHIIPAFQRYWKQKTGQDVRVRSSYGASGAQARAIIGGFDADVAVLSLEGDV
                     DQITKAGLITHDWRKAPHGGMISASVVALGVRKGNPKGVKGWEDAARPGVEVLYPNPK
                     TSGGAMWDVIAIYGAGLKLAEQRAGKPVAPEAAATQAVDLLTRIQRNVKVMDKSGRES
                     VTTFERGVGDVIVTYENELLPRVKSGRPYELIVPAETVWIENPAAVVDTYADRHKAKD
                     LAEAFVAFLHGPEAQAAFIELGFRPLDRGAVAPASGAALPQPARLFTIADLGGWESVS
                     TKLFGAQGVWTKIVEDVSKK"
     gene            complement(105642..106082)
                     /locus_tag="PK063_01280"
     CDS             complement(105642..106082)
                     /locus_tag="PK063_01280"
                     /inference="COORDINATES: protein motif:HMM:NF014173.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HMZ95693.1"
                     /translation="MKFSKKSEYGLRALLELCETYGGRVLQRHEIAERQNIPVEFLEQ
                     ILLALKRAGLLASRRGIRGGYSLIKSPEEITLGQVIRILDGPLAPISCVSKTAYQKCS
                     DCPYAAKPSCPLQQAMGEVRDAIANILDHYTLSRFAHTKLAEGS"
     gene            106327..107247
                     /locus_tag="PK063_01285"
     CDS             106327..107247
                     /locus_tag="PK063_01285"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HMZ95694.1"
                     /translation="MNFQDLILTLHRFWADRGCVIHQPYDLEVGAGTFHPATFLRSLG
                     PEPWSAAYPQACRRPTDGRYGENPNRMQHYYQYQVVLKPAPDNIQGLYLESLKQLGID
                     PKKHDIRFVQDDWESPTLGAWGLGWEVRLDGMEITQFTYFQEIGGIPLNPITGEITYG
                     TERIAMYLQQVDNVYDLQWSDGVTYGDVHHRSEVEFSRYNFEEGEVPMLMATFQSFEG
                     ECQRLLDKKLTLPAYDYCIKTSHMFNLLDARGAISVTERTSYIARVRALARRCAESYV
                     ADREAMGHPLIKQPAGAGKGTINHSPVTTK"
     gene            107269..109470
                     /gene="glyS"
                     /locus_tag="PK063_01290"
     CDS             107269..109470
                     /gene="glyS"
                     /locus_tag="PK063_01290"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: protein motif:HMM:TIGR00211.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009345 - glycine-tRNA ligase complex
                     [Evidence IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HMZ95695.1"
                     /translation="MPSKKTKTKTVSRAKKPASASRAKTPSTTELLLEIGTEELPYQF
                     VAPALRALQQGAETLLKDSRLTYGTVRTMGTPRRLVLLVEGLARQQASAVKEAMGPSK
                     AVAFDQSGQPTRAAIGFAAGQGVPVESLQVRQTPKGDYLFAVKPEKGQAVAAVLTQAL
                     PQLLAKLSFPKAMHWNQTGVRFARPVRWLIALCGGKVLPIQFATIKAGNYSQGHRVLG
                     AKVSSPKGFAVQSIAHYFKETERHSVIVDQDRRRAMILDQLAALAKSARGHLHQDEEL
                     LEQAVYMVECPLTILGSFKPHYLALPKEILMTSMKEHQGYFSLVDSKGALLPNFLAVT
                     NMKLANMQLIREGNERVLAARLADAKFFFDEDRKTSLADRVAKQLAVTFHQKLGSLHQ
                     KTQRVVAMAAHLAGQLGDDQLVHDCRRAAELSKADLLTGIVGEFPTLQGMMGGEYAKH
                     DGESATVSAAIREQYLPRAMEGELPESLAGKVLSLADRLDSIAGFFLVGLVPSGSEDP
                     FALRRHATAIVRILIESRLQINLAQAVRATQEGLAGQHVAAAPQPAKGGAPDVIGFLF
                     ERVRFYGKSAHQLRDDVMEAVLKSADRQSIDLTDLFDKMQSLQQITSRAEFDPLIVGF
                     KRAHRLTEKEQWDRKPVESGLFREPAESALYETVQQSHAAYAAAMRGGQYGQALDVLV
                     RMKGPIDDFFNAVMVNADDPAVRGNRLSLLKEVDDLFMSFADFSQIMVQGT"
     gene            109590..110003
                     /locus_tag="PK063_01295"
     CDS             109590..110003
                     /locus_tag="PK063_01295"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95696.1"
                     /translation="MMVVCNAVFLFGIWVTGLNFERLVRTPDIYDSRQDICLRLAYQH
                     VPGSENPVQFCSEWLNLADPTGKTHTFQKDAQLKQGADGSFYFDYGPFVDYRLFAVGA
                     FVVGIIVCGIRVTRHVVNRYRMRLEAAARHSVPTH"
     gene            110029..>111721
                     /locus_tag="PK063_01300"
     CDS             110029..>111721
                     /locus_tag="PK063_01300"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HMZ95697.1"
                     /translation="MAKKYVYYFGDGKAEGTGNMKELLGGKGAGLAEMTNLKVSVPPG
                     FTISTEACVEYYKRGKAYPPGMMEEALVALKKIERSMKAGFGDPDSPLLVSVRSGARA
                     SMPGMMDTVLNVGLTTKTVHGLALKTKNERFAQDSYRRFIGMFGSIVMGINREHFEDI
                     LKHKKRDLGVTQDTHLDAKALKELVVSFKELVKEETKRDFPDDPLEQLRMAINAVFSS
                     WYGARAVTYRRLYNIPETWGTAVNVVAMVFGNMGETSGTGVAFTRDPATGQRQFFGEC
                     LTNAQGEDVVAGIRTPLPVNQLEKFMPQAYKDLEVTYKKLERHYRDMLDLEFTIQEGK
                     LYMLQTRVGKRTGVAAVRIAVDMVKEGLISKKEALQRIGPDQLAQYLYPIFDAKEESH
                     CTPLGKGLPAGPGAAAGKIALTADRAVEMQAAGNRVVLVRQETSPDDIHGMNAALGFL
                     TARGGMTSHAAVVARQMGKVCVAGCEAIEVVDNQTVRIGTQTFREGDYLSVNGSTGNV
                     YGGDIPVVESEVIQVLQGKMEATASEKYQLFESVLKWADGVRKLKVRANADVPDQA"
     assembly_gap    111722..111821
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <111822..113033
                     /locus_tag="PK063_01305"
     CDS             <111822..113033
                     /locus_tag="PK063_01305"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248193.1"
                     /note="catalyzes the formation of phosphoenolpyruvate from
                     pyruvate; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HMZ95698.1"
                     /translation="DGVRKLKVRANADVPDQARIARSFGAEGIGLCRTEHMFFAEDRI
                     QIMQKMILARKREEREMYLDQLLPLQKQDFIGLYREMKGFPVTIRLLDPPLHEFLPKR
                     EDLMVEIAQLELTSGSQTVLEEKKRLLTRVEELHEFNPMLGLRGCRLGITMPEITKMQ
                     ARAIIEAACELAKEGTKIVPEIMIPLVGMVSEMKAQKDLVREVAAETMKRYGVKLSYL
                     VGTMIELPRAAVTADGIAEEAEFFSFGTNDLTQTTFGFSRDDAAKFIDFYKTANILES
                     DPFAVLDREGVGSLMRTAITGGRKTRPTIKLGICGEHGGDPSSVEFCHQLGLDYVSCS
                     PYRVGIARLAAAQAALAEAEKEKPKPAKSKPKAAKPSAVKSVKKSAKSAPAKKRPVAK
                     RVVRRSKRTSR"
     gene            113030..>113546
                     /gene="ribD"
                     /locus_tag="PK063_01310"
     CDS             113030..>113546
                     /gene="ribD"
                     /locus_tag="PK063_01310"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HMZ95699.1"
                     /translation="MKLSSRDREVMALALRLAAKGRGHTSPNPMVGAVVVNRGEIVGQ
                     GSHRKAGGPHAEVLALSQAGSRAKGGTLYVTLEPCSHLKKRTPPCVPLVISSGVRRVV
                     VAMVDPNPQVQGRGIAQLKRAGIQVEVGCLEPEARQLNETYIHWVQTGRPFTILKAGM
                     TLDGQIATATGE"
     assembly_gap    113547..113646
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <113647..114312
                     /locus_tag="PK063_01315"
     CDS             <113647..114312
                     /locus_tag="PK063_01315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HMZ95700.1"
                     /translation="ILKAGMTLDGQIATATGESQWITDEAARMQAHQLRADVDAVLVG
                     IGTVLRDNPQLTARTGGDPVRLAARQPLRVVVDSRLRIPSRAAVLKRQEEAHTVIATT
                     RAASVTKVERLRGQGIDVLVLPAAGGHVNLTALWARLGQLGVTSVLVEGGSDLNAAVL
                     RAGLPQRLMCFVAPLLLGGQDAKGVLGGLSPRRLREAVLLNNLRMTPVGRDMLIQADF
                     PTR"
     gene            114320..115648
                     /locus_tag="PK063_01320"
     CDS             114320..115648
                     /locus_tag="PK063_01320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95701.1"
                     /translation="MRSSLRPAYRVHPRRPGLLLSLVCIWLALLSVSLTHAAETASSS
                     DLAAQVWQYLTTQDSEQANSALASIMQRPDATLQAVQDILRKGQPHGLQPVGVLADEQ
                     VMVRDRPYRVSLSIPQSYEPTKDYALVVCLHGAGFTGEAYLDRWKSRLGEQYILACPT
                     YPAGAWFTRRAEDLVLATVHLVRERYRIDPNRIFLSGMSNGGIGAWLIGMHHAPLFAG
                     LAPMASGIDDVLFPFLENLRTTPVYIIHGSQDQVMPVELSRKLAGELKNLDYPYIYRE
                     HDRTHAMAGGHFFPREELPDLVKWFDTQHRTPVPKTVTVVRDASHLLPFGWVRIDATD
                     QIASFSEDLVDKRDDSIRKRIYARLTAQVTGPNRIDVRTDRVRQYTLYLNEDLVDLSK
                     PVVITTDGQPSFEGLLEPHVETLLRQARLRQDPAQLFPAHVTVTVPQRAS"
     gene            115663..>116035
                     /locus_tag="PK063_01325"
     CDS             115663..>116035
                     /locus_tag="PK063_01325"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95702.1"
                     /translation="MVRRIGPLAAVLTAALALCDSTGQAEPERCSLPSHHVGMVFPLD
                     QVDAAWTCRLEPIIAHYTTANKVGPIRTLLPEDVYLYLLEHPVMAAALVNRLDLGLYK
                     AEWRGPDEFWATDGEGTEGIVH"
     assembly_gap    116036..116135
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            116206..117381
                     /locus_tag="PK063_01330"
     CDS             116206..117381
                     /locus_tag="PK063_01330"
                     /inference="COORDINATES: protein motif:HMM:NF017760.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HMZ95703.1"
                     /translation="MTTSRSFFYLCTLGVFCFISYNLVRMPVLSLFAESLGAGPERIG
                     LIVSVSTITGVLLKLPSGALSDIYGRKMLLRIGVVAFGLPPFIYPFISDLNALTALRF
                     VHGLATAIFAPSALATVADLYKERRGAAMGTYTACTQSGSLLGPFIGGWLAHAAGFPA
                     AFVTAGVFGCIAILIFFSLHLDEPPPRVREKGLAPVITEMGKGFLAVARNRKVLITSS
                     TDAAKMIANGALMAFLPLYGLSVGLNAGEVGLMFSVQAVTSFLSKPVMGRISDRVGRQ
                     PLIVLGLVICAATFISIPHVGSFAVLLMLSSGFGFGEAVVSSSSAALVADSSEFKRLG
                     AGMGMQGTVMDIGHASGPLLAGFLIAHASYQGAFAVIAGIQILAAVAFWATMRTILR"
     gene            117561..118217
                     /locus_tag="PK063_01335"
     CDS             117561..118217
                     /locus_tag="PK063_01335"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HMZ95704.1"
                     /translation="MFSGIVEEMGAVSILNKGLAGTRLTIMASTIMTDLTIGASVSVN
                     GACLTAVARTDHDFSVDVSPETLSVTTLSDLTTGSPVNLERAMKLNERIGGHMVSGHV
                     DGIGAIRSRHQDGNALVLEIEAPKDILRLCVHKGSITVEGISLTINEVTERSFLVAII
                     PHTAKVTTLGLKQVGDKVNLESDLIGKYVERLLQDRGLLPPKPTPVIDKDYLQRRGLI
                     "
     gene            complement(118434..118949)
                     /locus_tag="PK063_01340"
     CDS             complement(118434..118949)
                     /locus_tag="PK063_01340"
                     /inference="COORDINATES: protein motif:HMM:NF013955.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IPT/TIG domain-containing protein"
                     /protein_id="HMZ95705.1"
                     /translation="MLGQRTTRGLLWSMVTGIILLGGVVPILAADDTPKAAGQAPAQA
                     KKAPEKKSVKKGEGRKTTTAPVKSPATKYASAETAAKAQACFGEAPKIESVKPDEGKA
                     GEKVTISGMNFGPAECLRSLSFGPGNAATFKLDSPTQITATVPASKRKGMAIMTVTTA
                     SGEDSKGFLLK"
     gene            complement(119002..120891)
                     /gene="acs"
                     /locus_tag="PK063_01345"
     CDS             complement(119002..120891)
                     /gene="acs"
                     /locus_tag="PK063_01345"
                     /EC_number="6.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003987 - acetate-CoA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0019427 - acetyl-CoA biosynthetic process
                     from acetate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase"
                     /protein_id="HMZ95706.1"
                     /translation="MSEKIDTLLKEGRVIQPSARIKAAAHIPDYDQAYKASIADPEAF
                     WGGVAKELEWFSPWSRVLEWNYPWAKWFVGATCNIAYNCLDRHTNGWRRNKVAIIWVG
                     ENGEERIFTYGELLRQVNRCANALKALGLNKGDRVTIYLPKIPEQVVAMLACARLGII
                     HSVVYSGFSAPALASRIQDAEARLVITADVGYDRGKTIPLKPVVDAAVQSCPSVEKVV
                     VVRRDALSVALTAPKEIDWADWLKEQNAVCAAEPLDAETPLYILYTSGTTGKPKGVVH
                     VHGGYMVGTYITTKYVFDLKEEDVYFCVADPGWVTGHSYIVYGPLLNGATILMAEGKP
                     DYPNPGRWWDLISRYGVSIFYTTPTAVRLLMKYGEEWPKKYDLSTLRILGSVGEPINP
                     EAWEWFYRVTGSDKPIMDTWWQTETGAILVTPLPSVPLKPGSATRPFLGIEADVVDKE
                     GNSLPANAGGFAVIKKPWPAMMRTIYKDPDRYKVYWNTIPNCYTAGDVCRKDQDGYMW
                     FMGRADDVIKVAGNRIGTAEVESALVSHEAVAEAAVIGKPHRTAGEAIKAFVILKQGY
                     QDSKELVQSLKDHVLKELGKIAVPQEIDIVSSLPKTRSGKIMRRVLKAKELGQDVGDI
                     STIED"
     gene            121153..122499
                     /locus_tag="PK063_01350"
     CDS             121153..122499
                     /locus_tag="PK063_01350"
                     /inference="COORDINATES: protein motif:HMM:NF012862.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="caspase family protein"
                     /protein_id="HMZ95707.1"
                     /translation="MITCLAALFVAGMSTDHAAAQVGKPEGLYYKSWAVVVGIENYLV
                     APKVPGALESSHAVAEALRGLGFDEVIEIQDKEAASKRLLHILNDYLPRKVGRQDRIV
                     FFFTGHAGLTQDSQAKDSGFVVPWDAQLNNPAKAITLDQLKEFSRRSASKHILMVFDA
                     NLRGWDVTAPQPLSLEGRLSPEDDTEKRSVQVLTAAEKEESVVRTSGQSAFVTALVAG
                     LKGAADLNKNGWIMASELAAQVKQDVERETKGAQHPQLLQLEGDGDVILVEGRKAMFS
                     VGKEPSTEADRMKEARVQYEQAFALLQQQKSAEEALERLNRAITYDPSFGDAYVLKSF
                     IRLEVLPNLEESLAAAQAAVQHAPQNPDSHYSLALALEKKGQHQEAERAMLQALAVNP
                     AYTDVYFSLGTLYADHLNEPQKSVDAFRRYLELGGQSERATLAIQGDRAPGEKPAP"
     gene            complement(122591..122761)
                     /locus_tag="PK063_01355"
     CDS             complement(122591..122761)
                     /locus_tag="PK063_01355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95708.1"
                     /translation="MADVQIEDGIIRVVQLDIQDPKAAAVLAEYPQVRWPEITRRALK
                     IGLGYLKGGGKD"
     gene            122998..123564
                     /locus_tag="PK063_01360"
     CDS             122998..123564
                     /locus_tag="PK063_01360"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95709.1"
                     /translation="MSRVEGAFSKFTGSALMLVLLIGLTACGGPPNWVKKGSGAFNEK
                     SDKSFYGVGSVVGVRNEPLAWDTAENRSRAEIAKTFETYTAYLMRDYAASTTAGDFSR
                     NSEEQNIERAVKTFSAVTLNGVKPMDRYKDEKSGTYYVLTKLSLEDMKNNLEQAKELN
                     SQVRDFVRKNADRLFDRLEKEEDKRATK"
     gene            123604..124233
                     /locus_tag="PK063_01365"
     CDS             123604..124233
                     /locus_tag="PK063_01365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator LpoB"
                     /protein_id="HMZ95710.1"
                     /translation="MIEWREHSVLRTCAVGLLVGCAAVVSGCGHETKVTRVDTGTVTD
                     LSGRWNDTDSQMVAEAMVKEALANPWLGNFTKGKNRQPVVIVGTVLNKSHEHINVQTF
                     VNDLERELTNSQKVTFVAAKGERDEVREERREQAVHAREDTQKAPGKEIGADYMMRGS
                     IATILDEQDGAKAVFYQIDLEMVDLENNVKSWFGQKKIKKVIEKKRTIF"
     gene            124311..125744
                     /locus_tag="PK063_01370"
     CDS             124311..125744
                     /locus_tag="PK063_01370"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95711.1"
                     /translation="MHSVIGWCLLWVLSGCGLSSNHYLLIDQSLAAHDARRADAIMAE
                     AESEYGPRNRLLYSMDRGMTLHLAGEYMQSNAQLESAAQEVERLYTRTIRTETAAFLT
                     NDNVLPYEGDPYEHVMINIIKALNYAAMGQLMEAVVEARQIDHRLNVLSDAAKEKDGY
                     REDAFARYLTGVLYEATGDLNNAFIAYRKAYDIYDATKSWARTPMPPMLRADLLRTTD
                     ALHMTTEFEEYRRLFPETRWLPRADQQNLAQVVVIGYNGRAPRKEDAFLDIPISLSAL
                     QLVLLNRGVIHASNRQERRVADSVLYGLNGRVVRVALPKLILQKTQVVHETVTLIPRG
                     GEPISATSELVYNGTALAERSLSDRLPGITTKALARAAVKFAAAEAATRGSQHAVNKG
                     DAPWVGLLVGVLAHGLAVASESADTRSWRTLPDEIQISRLWVPPGEYESRIQAMVRGN
                     GTPQVEGPRPLVLRAGQTLFLIERVML"
     gene            125759..126877
                     /locus_tag="PK063_01375"
     CDS             125759..126877
                     /locus_tag="PK063_01375"
                     /inference="COORDINATES: protein motif:HMM:NF014248.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPP20 family lipoprotein"
                     /protein_id="HMZ95712.1"
                     /translation="MVSDRGTRISLVALVMLLCAGCGWVGGPSRPSWIDGSSTQFPST
                     QYLVGVGQADSRPQATEQAYAAVSRIFKAEITAQAKDWESYLVVESRGQTSTQRKLIL
                     DNVTRVTTDKVLENVQVLDTWFDQKARQYYALAGMNRAQAESAMLERLADLDRSIQTE
                     VTEAHQAQDKLSHVRNLKRAAKNLVLREAYNTDLRTIRSNGQGHPAAYRVAELTAELE
                     HYLAANMGMAVEVSGEQAEPLERALIEGLTQEGFSVVGSGPGAATAELLITGTVRMWP
                     IQVPDPQFRYVRWCTDAVIEEVSTHRVIGAVSKGGKEGHVTEREAAAKAVRVMQQEFS
                     ADLAQAVAAHIYGERDLSVSSSAPSGCPKEAGQPPLSR"
     gene            126912..127160
                     /locus_tag="PK063_01380"
     CDS             126912..127160
                     /locus_tag="PK063_01380"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95713.1"
                     /translation="MAKTGTRKAGEQAGGGRRMSSQAMKKHLRERLTADTQQVLKSDI
                     VSIFRKQGYYEELPLDELQDRLSKLQSPLADSLLKGRV"
     gene            127162..>127586
                     /locus_tag="PK063_01385"
     CDS             127162..>127586
                     /locus_tag="PK063_01385"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family
                     toxin"
                     /protein_id="HMZ95714.1"
                     /translation="MPYYYFDSTALVKRYSMERGTRIVNKLMVKRGKVAILPMWSVTD
                     FYSALSVRSQQGEITRDDCYSVLYKFEMEASQGLFQFISPTMDTYLAAKELILDYPAL
                     RSPQLLHLALALELKPLRLTVVSADKQLLAACRPAGLHI"
     assembly_gap    127587..127686
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(127949..128491)
                     /locus_tag="PK063_01390"
     CDS             complement(127949..128491)
                     /locus_tag="PK063_01390"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95715.1"
                     /translation="MRNGIHIGRCEHCLAASILSFFILVAAAGIGQAQVMGEEAELDR
                     LRAKAEDAMGNDDAEGAAMNMGRAALMAAQLGKRQTEPALRQVFKSTEHLYRSQEHGY
                     RGLALFRRAGGELPASAGVCGSLQLAQLELQHAQETLASSETPDRPGAVSPKLPAIRQ
                     TADDWAIVLASMMGEFRCPN"
     gene            complement(128488..129564)
                     /locus_tag="PK063_01395"
     CDS             complement(128488..129564)
                     /locus_tag="PK063_01395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HMZ95716.1"
                     /translation="MRCILSLVILGVLLLYGDPSWARREALTAEQKSQMERIDRVLIT
                     VLALSDKGSVDAGPLAEVAANRMKEFGYTPVTDPTQPHDVELKIKCEQKKTWEGTTTM
                     GSDADLPDAPSRIWKGPACQLGYLLNGKKMAWRKEVRTDFDDAQAAATLAKAGDPTSF
                     AMGRLQARLEEYDFPALITAEWGQEARLFRLYDDPKTPVARKVKLVALFGDLFSVKAI
                     PRLLDGLNGPDRSIAKASALALGNIGQKDTIPVLIKTMKNGAPDLRAPAAKALGIVGA
                     LHGDFTIVDPLLETLNTEDVAVKTEVAWALGKLPDMRAYEPLFALQKSLYHVHENDAD
                     PNLVKLKEAVNWSIKQIDTWEHVQ"
     gene            129681..130511
                     /gene="proC"
                     /locus_tag="PK063_01400"
     CDS             129681..130511
                     /gene="proC"
                     /locus_tag="PK063_01400"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HMZ95717.1"
                     /translation="MLTGRQIGFVGGGNMAESLLAGLLRKGLSSPGRLVVSDPLASRR
                     ELLSRNLGVSVTPDNQAAVRGADIVVLCVEPQVLDDVLRELAPSLPSDPVIISVAAGY
                     PLSRVQHHLPSATRLIRAMPNTPSAIGEGVTAMSLAPGVSSEDRETARQLFESVGMAV
                     VVEERLLDAVTALSGSGPAYVFAMIEALADGGVLGGLPRSTAQLLAAHTVAGAASMVL
                     EQGEHPAVLKDRVASPGGTTIAGLYQLEQRKLRATLMSAVEAATQRSQELGKTENHHL
                     "
     gene            130527..130721
                     /locus_tag="PK063_01405"
     CDS             130527..130721
                     /locus_tag="PK063_01405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95718.1"
                     /translation="MQYWVKVVFADNQELLVKDAIRHTISEDMEVLEVDSAKEVIIVP
                     MKQIKYIACDATVFAQKSKT"
     gene            complement(130718..131914)
                     /locus_tag="PK063_01410"
     CDS             complement(130718..131914)
                     /locus_tag="PK063_01410"
                     /inference="COORDINATES: protein motif:HMM:NF012798.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HMZ95719.1"
                     /translation="MARKEGKDRGITQRKGREGWWVRVYEEGRQTWHKCDTKSQARTL
                     YGKLKAEAREGKLFPKQKTTKSILLKDYFVTWLKNQPARGKKITTIKTYESRLRKHAL
                     PAFGTSQLSAISRPRIKAWAAGLLEKGLDFDTALNALLTLSAVLTEAVEDGLITHNPA
                     LRSGKLLKRPATIEESELAIFTPEEEGLLLETIRRDRPLFYPMALTFFRTGLRAGEVL
                     GLHRGDLNFHSRSIYVQRNWSRGILGTPKNGKARRVDMSQGLAKALTEWIELQDLEAA
                     AAGHAAPEVLFPGNLGGTRREPSYMAENWLRYKLWFPMVEKAGLRRLDMHSVRHTYAS
                     RLIANGENLKYVQEQLGHASITITCDTYGHLIPGGNRQAVDKLDSLKIGSGTVTKTVT
                     NAYENS"
     gene            complement(131889..>132302)
                     /locus_tag="PK063_01415"
     CDS             complement(131889..>132302)
                     /locus_tag="PK063_01415"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95720.1"
                     /translation="GEGFRGTLPSRGEAKEIQGMVLGSLEKLWKNAVAAFTFPQFTII
                     VTLPIEDARKGSVFVATKRKVKEFEYRFAHLLMDYSGRIRRCPECQRIYLAIRVDQIY
                     CGPRCQTRVATRKWRENHKTEQQKESHRGKKRRQG"
BASE COUNT        26723 a        36414 c        40221 g        28144 t
ORIGIN      
        1 atcccgtctt aatgcgatcc acaacgaaag gatagctgcg tgcagacgac tgcgtttacg
       61 agttttgact cccttggtct gtctcccacc ctgttgcgaa atctcacgaa agctggtttt
      121 tctgaaccga cggccattca ggctcaggcc ataccgcatg ccttgtcagg gcgtgacgtg
      181 ctgggctgcg cacagacagg aacgggaaaa accgcggcat ttgttattcc gatgctggag
      241 cggttgaccg gcacaccgaa gggacagcca cgcgcgctca ttttggctcc gacgcgtgag
      301 ctggcgatac agattcaagc gacgatcgat acattgggcc gcgacctgca gttgtttgcc
      361 accacggtgg ttggcggagc ggacatgcag gctcaggtga gagggttgcg gcaacgtccg
      421 gatattatcg tggctactcc ggggcgattg ctcgatcata tgtggaatgg aacgatcagc
      481 ttattggcga tgaacattct tgtgctcgac gaggccgatc ggatgctgga tatgggattt
      541 gcccagcaga tcaatcagat tctggatgcc atgccggaag agcggcagac attgctgttt
      601 tctgcgacga tgcctatgga tctggccagg ctggcgcagg ccagcgtaaa ggatccggtg
      661 cgcgtcatgg tggcgaagtc agcaacgacg gccgagggcg tcgcccaggc tgtgcatcac
      721 acaacgcatg atcggaaaaa tgcgctcctg atgtccctcc tgcagtccga atccgatacc
      781 gtgctggtat tcgccagaac gaagcatcgg gccgaccgac tcggcaatct gttggatacg
      841 gccggtcacc gggtggcggt gctccacgga gggcgtacgc tgccgcaacg gcgagccgcc
      901 ctggaaggat tccggcgagg gacgtatcga gtattagtcg cgacggatat tgccgcccga
      961 ggcattgatg tggcaaatat tgcgcacgtc atcaattacg acgtgcctaa ttgcccggaa
     1021 gattatgtgc atcgtgtcgg gcgtacggcg cggatgagga ccaccggccg tgcgacgacg
     1081 tttgtgacgg cggaagacca ggaacaactg cgagccatcg agcgattgct gggccaagcg
     1141 gtgcctcgcg ccgagggaag cccggcttca ctgccgcctt cgtcacgacc ggatggtcac
     1201 gcgccacgca atgaaccgga gcggcgccga cgccgtggcg ggtctgccca gggatggcgt
     1261 cagacaactg atggcggatc tcgagaggcc aatgggggaa tcaaaaacgg aagcgacctt
     1321 gggccggtct cttaatttgg acgagtctac gttgcaaggg aggaagaaag gtgagtgatc
     1381 agaaccaaga tgcaccgcga gctgcgaccc agtgggtcag aattccggat gggacgatgg
     1441 tgcagcatcg tttggacggg caaaagggac atatcgacgg attgacggaa attgtcaccg
     1501 gtccgagccg gaatcccgat ggacggacac agtaccggat taacgtcggc aagggagatc
     1561 gagtgctgat tgcggaagaa gatcttctga ttctgacgga tgccgaagga atggtccgaa
     1621 tggcgaaaga gaagggcgag tatcgctcac tggtcagtaa gcagttgcgc gggatctttg
     1681 gggaagaccg ctttatcgtc aagacatctt aacgacgatg ccccttcgcg gcctcccagg
     1741 aacctctgct agtacagggg ttcctggggc ccccatcgta acccttccag atcgggatct
     1801 tctcctcccg acgtcgcagg ccgttccggc ttctcggcct tccgttgcac ccgacgagct
     1861 tctttctccc gctgcttcac ctgcctggct ttttctcgat cgcgtttcgc gatggtcgtt
     1921 ttgcctgctc gtgcgatggt tccctccttc tattcacctt ccccgatcgg ggagcaaata
     1981 ggcttgcctc gttatgatcc agctggccga cgggcggttc gggttgtact ggtccgtgcc
     2041 agagtgcgcg ccggacgtgt ctgggtttgt tctgaccggg cgcgggtctc tgcaccaaat
     2101 ccggaactgg ccagtgccgt cacttcacgg cggatctgat ccatcggcgt ctcatgtggt
     2161 tccacggagg gatcaaccag gccgagttcc gtccaccgga ttctcaactt gggaacggtt
     2221 cgcttcttct tatggttggg tttgttgcca cgccagacgg acgttatctt catcgtacac
     2281 tcctttcggc gaacaacagg atggcgatgt ccaggccatc aaactgggtg cagtggggga
     2341 ggaatactct cgccccatgc tttgcccatt tcctgtcaga atgtaagaaa tgggccgtag
     2401 gaggagcgta acttggggat gcgatcgcgc ggcaatgacg gaaacgcgaa gcgtgggatc
     2461 tcgctcgtta ctcgtacggt ttagcaactt atcatgctta cgacaccttg gtcaaatgag
     2521 ccgtccgcgg tcaacaatac ccggcgattg aggcggatag ctcctcccgt tcaaccatcg
     2581 atcttatgct gcttacgaag gagcacgaga gtgatgcttg aaatgtcagg gagttaggcc
     2641 atggggctgg tttccgatga tcgtgagacg ggccggcgaa tgccaagttt tcgtaagcgg
     2701 ctgcgcaggg tttctggatt gagtcctaac agattggctg ccccttggtc gccatagatt
     2761 cgccatttgg tccgttccag tatcatgatg atgtgatgcc gttcgagatc ttcaaggctc
     2821 tcaggctgat gcgtcaagac ggcccgtcct gcccggacga tcggaagcaa catttcgtcc
     2881 acggtgactt gggatgaact ggaaaggatc accgcgcgtt caatcacatt ttgcagctcg
     2941 cgcacattgc caggccagtt gtaagagagg aggcgtgcca tggactgtgg gtcaaaggtc
     3001 agatgcggcc gcttgtgctt cgcgccgatt tgcgtgagaa aatgttgggc aaggagctga
     3061 atatcctcgc ggcgttcccg gaggggaggg actgcgatgg gaaagatgtg gagccgatag
     3121 tacaagtcgg ctcggaaagt tccctgttga atcgcggcgg acaagtcggc attggtggcg
     3181 gcgatgagtc gaacattcac ggaaaccggc tgcgtgccgc cgattcgatc gaccatgccg
     3241 tcctggagca cccgcaatag tttggcctgg gtttccagcg gcatttcacc gatctcatcc
     3301 aaaaacaatg ttccggtgtg agccagttcg aaacgtcctg ctcgtcggag ttgtgcgccg
     3361 gtaaaggcac cgcgttcatg accgaataat tcactttcga tcagtccgga agggagcgct
     3421 gcgcaattga cgcgaataaa tggcttttgg ctccgcgcgc tcaagtcatg aagggcctgg
     3481 gccagcactt ctttccccgt tccggtttcg ccgagcagga gcacggttgt gtctgtcggc
     3541 gcgaccgcct tcacaagctc gaccaccttg ctgaatgatg aagatgctcc aacgagcaac
     3601 cgctgattac ggctggcctt cacctcttcg gcgagatact cgttctcgcg gcgcaaccgc
     3661 tcgctcaatt gtttgatctg ctggtatgcc aggacgtgat cgatggcgta ggcgatctgg
     3721 gtggcgactt gctgcaaaaa cttgcagtcg tccgggtcgg gctcgccacc atggacgctg
     3781 ccgatgttga gtgtcccgag acaatgctca cgcaccagca gcggcaggtt aatcatgcgg
     3841 cccaatcctt cttgggcata aaaacggtct tccagaaaca cttgttcctt ctgaaggttg
     3901 ccacgaatgt gtaggcgccg gtggtcatac acccatccca ccgcgctgcc ttcacgggga
     3961 atgacgctat catgcgccag ggccggactg gccatgttgg tgatgacggc gtaaaaccgg
     4021 aaggcgtcag tattggattc gtacaaggta atccccgcac gatcccatgg aatcactttc
     4081 tggatttggt cggcgatgac tcgccagagg ctctcgatgt ctcgctgcga gttcagtgca
     4141 ttggtgactt cgagaagtgt ttcaaaattc agggttgcgc gttgcatgac gaattaaaaa
     4201 ttggtccaga gttgtacgat gccccagtcc tgatccattg aggtgccgag ctggtggcgg
     4261 atatagggcc cagagaaaaa atggccatag atgacggcca ctgacacggt accgtccgca
     4321 aacatgtgac tccatgcgac atcgagttcg tcgcccacgt gggtcgtctg gttgtcggat
     4381 cgtgaaaaaa tgagtggccc ttgtgatcca cggtaccaat tgtcgcgagc gcttgccaag
     4441 tacttgcgca tggcccagac ttcgacgtga tctcgagtgg tcggcctggc ttgcaggttc
     4501 acctgcggct gaaccgtgtt cctccaggcc ccgttcagca tgtagccgac gtgcaggaag
     4561 tttgtgggaa agaaattttc gaacgtgttg gcattgccac cgcagctgcg cgcgagagtt
     4621 ccgccgggtg tgacgcaatt gctgtctccg tctcccgacg catagtcaaa cccgatcgcg
     4681 actcgtggct tccaaggatg ggcataccac gtgtggccaa gccaggtgcc agaggcccag
     4741 gcattaatgc tcaggttgcg ctggttgtcg aagccaaacc cgtccgcggt ccgcccgaat
     4801 tggtacgctg tttcatgcac cagatcccaa ttgccatcgc gtagttcgag acgaagcccg
     4861 accatatgtc tgagctgaga ggccgacttg ggaaggtact gcccaggatt ggctcgttct
     4921 ggaagccggt tgtagtagag gacgtaatac ggctcgacaa tcattcgcgg cacgcctcgg
     4981 atttgattgt aaaacactac catgtcgaca tcgcttcccg cgtcggccgc atgctgcgcc
     5041 acggccggat tgcagacgga ctgggatgtg acgtcctggt tgcacgttaa aagattcggg
     5101 gtcagacttc cgccagggtg cccttggccc aggtcagtct ccgaatgacg aaaccagccg
     5161 agtttcagat caaaatcggt gcgggcgtaa ctcaacatga cgccatcgtg agaatagccg
     5221 gtattcgccc aatcgaagtg tccgaacaaa cgttgattgc cgaacacgac gtattggcgg
     5281 ccgaacttcg cactgaggcc ttcgacaccg gcgagattcc ggatgagcgc atagcccgct
     5341 cggatcccga gccggcattg tcccggtcgc tgagttccgc attgatggtt ggcggcgtct
     5401 gcactctggc ctccatccgt cgggttgccg ctgcctcccc atgtcgccga atcctgaagt
     5461 tcaacgtaaa aattgagagt gggcgaagga tcatacccga ggccgagccg cgcccattgc
     5521 tgaatgaaga agtcgctggc cttggagcca tcgtgggcgc tggtgccgga tccggagagg
     5581 ttgaggctgt tgcaggcgcc attcatcgga ggtcctcctc caaaacagac cccgctacgc
     5641 cattccggtc tgacccgcag gtcggcgcgc atccagaaat tccggatgtc aaaggcagca
     5701 gggggaggca gtagtgcgac ggggtcagtg tcgatcacca gactttcagc cgacgagaaa
     5761 agcgccggtg aggtcggccc atagccgaca tgccccgctt cggccatgag ggaagtcggg
     5821 gcaaggatcg cgcccgatgg aagtgtgaag gcaaaccaca acaacaggaa tttccacatg
     5881 gcgaagatgc ggcgtctcga cagtcatgga acatagaatc ctccatttcc ccaagtgtcg
     5941 gggcgaatag gccgggggcc acttggtagc gcacccccgg cagattcact gttcgacgaa
     6001 acgaacgacg actagaagct cattcccgcc cgctcttcca tgttgcgcat gaattcctcg
     6061 tgctctttca cagtgtccgc gcctttcgcc cgaatgtgcc gatcccgcgc gtggaattca
     6121 tcgggtgtca cccgatagca aaaatcccac aaggcctcgg cgctatgctc gtcaatgccg
     6181 cccacgcgtg cctcaagcat gaccatcaag gcgttgacgc cgtcatacgt cgcacgtcga
     6241 ttgccggacc ggtgcaactc tcgtatcttg ctcgtctgtt ccacataggg ttgaaaactt
     6301 cctggaatca gatttttttc cgccatggtt tgataggtca ccacttgacc gagcaactct
     6361 tcagcccagg cggcggattt ttgattactg ttccatacga ccggttcagg gttattcgaa
     6421 aatgcctgcg cctgggacag gtccagcagg ggccaggctc cgatcaggaa cgctgtcgaa
     6481 tacagtgcga tggtgttctt catgtgatcc tcctcaggta gcccggcctg gaggccggag
     6541 tgatgtgcat gcttgggcaa atggtcatcg atggttgctg cccctacatc agcaacaccc
     6601 atgcctcgga gaacgccatg gattgcggct ataacctttt gatttcctga gggagcagtc
     6661 gtcaggagcg gatcgagggg tatgcggatc gtgattggca acggtgggcg gtgaaatgca
     6721 acggttccac cgcgagggaa ttgcagcaat cagttggagg agccgcggtg caccgtttcg
     6781 acgagatcac agcggtgatg aagaatgttt aaggaagagg acagacagcg ctggcaaggt
     6841 acaggtgatc gaatgcgttc gtccatgcag gggtacaggt gtcgcttcta tcccgccggc
     6901 atttccccag ccatggccgc cgtagatcgc ggcatcgctg ttcaagagtt ctttccagta
     6961 tccaccgcgt ggcgcgccga ggcgataatt gggacgcggc acaggggtaa aattgcacac
     7021 gacgagaatg atctcgtcag tggcccggcc ttttctgatc agactgatga cgctcgattc
     7081 cgcgtcccgg cagtcaatcc attcgatgcc ggagggatcg acatcgcctt catggagtga
     7141 cgattcccgg cgatacgtgt gattgagatc cgtcacccac cggtgcaccc cttgatggag
     7201 cggtaactcc agcgcactcc attccaactg gccatcatgg gaccattcag ccggttggcc
     7261 gaattctcct cccatgaaca cgagtttctt cgcggcttgg gagtacatat gtccgaagag
     7321 cagacgaagg ttggaaaatt tctgccattc gtctcccggc attttcccca gtaaagagcc
     7381 tttcccatac accacttcgt catgcgagag cggtagcacg aagttctcgt ggaaggcata
     7441 gagcatccga aaggtcaggt tgtgatgatg atatttgcga tcgatcgggt ccttttgcat
     7501 ataggtcagg gtgtcgtgca tccagcccat atcccatttc aatccgaagc ccaggccacc
     7561 gaggtatgtg gggcgagaga ccaggggcca agcggtggat tcttccgcaa tggtttggac
     7621 gtcgggaaag tgccggtaca cttcttcgtt cagccgcttg aggaaagcga tggcctcgag
     7681 attttcgcga cccccatatc gattaggaat ccattcgcct tctttccgcg agtagtctag
     7741 gtacagcatg gaggccaccg cgtccaatcg caggccgtcg aagtgatact tgtccagcca
     7801 gaagagtgcg ctgctaatga gaaagctgcg gacttcattg cggccgaaat taaagataaa
     7861 cgtgttccaa tccagctgaa atccttgccg cgggtcggca tgttcataca gatgcgtgcc
     7921 gtcgaaaaac cccagtcctt gttcatcagt tgggaaatgg gacgggaccc aatccagcag
     7981 aaccccgatc ccgtgatcgt gcaacgtatc gatgagatac atcaggtcct gcggtgtgcc
     8041 gtaattcccg gtcggtgcga aatagccggt tgtttgatag ccccacgaac cgaaaaaggg
     8101 atgatccgtc agcggcataa attccacatg cgtgaatccg gtcttctgca gatactcggc
     8161 cagcgggact gccagttcgc gataactgag cgaccgattc tgttcggcgg cgatgcgttt
     8221 ccatgatccg acatgcattt cgtaaattgc catcggcgcg ttcaatgcat tggcgcgccc
     8281 gcgtgtgcgc agccagtcgt cgtctgtcca tgtgtaatcg aggtcccaga caatcgacgc
     8341 cgatttcggc gggatttcat taaagaagga cagggggtcg cttttatcga cgcgatagtc
     8401 ggcatggcgc gagtggacat ggtacttgta taacgctccc ttggcgcact cggtgatgaa
     8461 cccttcccac aggccggagt ctcctcgtgg atggaggatg tgggcgtcgc gattccagtc
     8521 gttgaatgag ccgatgaccg acacctgttc tgcattcggg gcccacaccg caaagtaagt
     8581 gcctgcctct ccgtgagaaa ccatcgggtg cgcgcccagt ttgtcgtaca gttgaaattg
     8641 tgtcccctca ttgaagagat agacatcatc atcagtcagt ctggtggttg ccgaaggccc
     8701 cggattctgt gcaaggttct gtggactcac tggttcacct cgtctctcac ctgtccgcct
     8761 gaacggggaa tggccccatc gttacgcaca tcgtcgttgt cagcatcctc aatggcgata
     8821 gaggcactca tcgagtgtag gaggccggtg agggggatgc ccacccaatc cggtctatta
     8881 ttcagctcat acgtcagttc atacatggct ttatccagca tctgcacatc caataagagg
     8941 ttgaactcgt ccggtgattg aggggaaaac ggcgcctgcc ctgcggtagt tcgatatcct
     9001 ctcagaaacg ccgtgcgcac cgttcgatac cagtgctcca tccacgaaac caagtcgagc
     9061 gacgccggta ggtgagggcg gcgtgcttct cctgtgcgca atgccacatg ggcggcgtag
     9121 tgaaaggagc gaatcattcc ggcgagatcc accatgggga ggcatttcgc ccggcgctca
     9181 gccaaaggct ttgccggttc tccctcaaaa tcgatgatga caaaatcttc gcctgtgtag
     9241 aggacctgtc ccaggtgata gtcgccatgg caccgaatgc gcaacgcgct caagggttgc
     9301 cgcgccagtg ttgctaaccg gctgagaagc ggagactcct gttccaggac cttttgagcc
     9361 tgttcctggt ccgtcacaga gagtgaagga agtcggcgtc gcagtaatgc caaggcctga
     9421 gtggcagact gttgcatggc gtgaacgcgc gactgtacat atgacgtggc acagggctcc
     9481 ggcgtaaacg cggcctcatc actcggttgt gcgagtgcga tatggagttc gcccgtacgt
     9541 tggcccaata ggtgtgccga atcacggtag cccaaaagaa gatcactggt cgtgggttcc
     9601 tgattcgatc ggtcatgcgc cggctgccca gcctcttcct tcctgtgatc gagcgcgagg
     9661 atgccattta tgtagcggga cagttgttcc agggtgtaat cccaggcatt ccctcgattg
     9721 gcgacaaagg tttgtgccag agcgagcgtc atcggctcgc cagcctcttg tacgtattcc
     9781 agtgcaccga tgaggctggg ggagtgtgta aagtgtcgtg ccgtaagggc acggccgact
     9841 tccaattctg gattcatgcc gggctcgatt cgtcggtaca gcttcatgat ggcacagtcg
     9901 ccaaatttca ccgacgtatt actctgctcg cctttcagaa cggaactgga ggcggcatgc
     9961 gcgcagtggg acgcttcatc aaacaattcg gtagccgatc cgaccaacgt gccgattgat
    10021 cnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ntgggacgct tcatcaaaca
    10141 attcggtagc cgatccgacc aacgtgccga ttgatctccg gaattgcccg cgtcggccca
    10201 tgctgtccag cagcgagtac gcgcagtccg gatgccataa cgcatcgtac agaattccag
    10261 cgagtgccgt tccgttctgg aggacagtca gtgccccgat gatcgcctct ggatagtcat
    10321 gtttgacgcg atctgcctcc gcatcaaaag cggccgtcat cggcagtgtg tacctgtccg
    10381 ctcctccttc aaggtaggac acgtcgatca atgccaggac catagtgccg tccccatgtt
    10441 cctgctgtag aacgtctgca agcttggccg agcgaatcgt tttcgctttc ccgccaaacc
    10501 atcgcgaggc cgtaaggaag tccggcagca gcttctcgat ttccgcccgt gacgagcctt
    10561 caaaggcgac tttccaattg tcccgcacgg tgatcatgag attggtatgc ctgcgcaacg
    10621 gttagaggta ataatcaaaa tcctcttcgc gccgaagatt gcggcgcact gtaaaaattt
    10681 gtgccggcac tgaatgtggg tcgagctgga cataatttcg aggtccctgc cacacgtaat
    10741 aggcctgcgt caggagatca tggacttgaa acggttggtt tgcctcgatc ccgagagccg
    10801 ccagattcaa ttccatccag cccgaatgaa catggtgcgg gctgagattc actacaatga
    10861 gaacgacatt cgagccgtcg gccgattgtt tgctgtaggc caggagatac tcgttgtcga
    10921 tggggtgaaa ctgcagactc tcgtcgcgat gtagcgcagg attctcgcgg cggatacggt
    10981 tgatcaaact gatgaattct ttaaggctat caggtcgatt gatatcccat cgccgcactt
    11041 catatttttc agaatccagg tattcctcac tgcctggttt ctgcggacgg ttttcataga
    11101 gctcgaaggc cgggccataa atgccataac tcgatcccaa ggtcgccgcc aacgccagcc
    11161 gggccatgaa caccggacgc ccgccgtgct gtaaatgctc ggtgaggatg tcgggcgtat
    11221 tcgtccagag gttggggcga aaatattccc gtactgagga ggtcgtgagc tcggtgaaat
    11281 agtcggtcag ctcctgcttg ctgttgcgcc acgcaaagta ggtgtacgac tgcgtaaaac
    11341 ctatcttcgc taagtgatac atgactttcg gcctggtaaa cgcctctgcc aggaagatcg
    11401 tttccggata ggaggctttc acgtcgctga tgagccattt ccagaacaga aaaggtttgg
    11461 tatgcggatt gtccacgcga aaaatccgga tgccgtggtc gatccagtac tggaccacct
    11521 cgcgtagctc tttccaaagg tctgggtacg cgtctgtctc gaaatgtaat ggaaagatat
    11581 cctggtactg tttgggcgga ttttccgcga attgaatggt gccgtcaggg cgtgttttga
    11641 accattccgg atgctctttg acgtaaggat ggtcgggtga gcattgaaag gcgaggtcga
    11701 gggcaatctc gatgccgttc gtctgggcgg cagccacgag ttgctcgaaa tcgcccaggc
    11761 ttcctagttc cgaatgaatt gcggtgtgcc cgccatcgcg agatccgatc gcccagggac
    11821 tgcctaccga agacgagtca cctcgcggat tgttatttcg tcctttgcgg tgggtttcgc
    11881 cgataggatg gatgggcggc agatagagca cgtcaaatcc catctccgcg atgtagggga
    11941 gccgtgactc gcaatccttg aatgtgccgt ggggctgttc ttcgtctgtc gtcgaacggg
    12001 gaaacatttc gtaccaggcg ctgaatcgcg ctttgggccg atccaccacg acgatgagct
    12061 cgcggtcata tgtactcatc agggcgtgat caatacagtc ggccatgatc tctgccgtgt
    12121 cctcttcgag caggaggtcc agcagagcct gcgaagcgag atcagaacga gacacccttg
    12181 cctggatgtc cttcaggcgt cgtcgggata cgtcaggcgc gggagcggtc gcctgttcga
    12241 tcaagtgctt cccgatcaag atctccaccg tgacatcctg ccgagcccgc agccgtttac
    12301 gcatgtcacg ctgccatgtc gcgaagggat ccacccatcc catgatgccg tagcggtatt
    12361 ggcccagttc cgtgacatcg aacgaggcac gccagcggtc attgaccagg gggctcaacg
    12421 gcgtagttag ccattcctcc tgacgttcat gacgggaacg cagaatgcct tggatcacgt
    12481 cgtgtccgtc cgcgaagagg tctgcttcga cgatgatcgt ctctccgacc actcgtttga
    12541 tcggatagcg cccgtcgtca gcttgtggct cgacatgttc aatggccacg cgcaaccggc
    12601 cctcgcccaa gacaggggac gaggcttgct tcttccggct cgccggcttg gacggcacgt
    12661 ttcgccgagc atctgtaggc cgcgcttttt tcataaatgt gataactggt cggccttgtg
    12721 ttcgtgttga ctgaagcggc gttcaagaat ctcccgcatg agatgccgcg cgcccaagcc
    12781 cacggccagg gccagggcga gcacgacacc gccgaaggtg atggagaacg cggcgatgac
    12841 aatttccttc gcaatgccta actgggtgag caccatcgcg caggtgaata gcagcagccc
    12901 ccaccgcacc agtcccgcaa cgacgcgcgc ttcctccacc tgggcgttca cggcggcgat
    12961 caatgcggcc tcggcaaaga aattggcgca cagtactccc acgaggagca caagggatgc
    13021 ggccaggaca ttcggtaaga acgcgacgat ttggctgatc aaattcgccg tggccggaag
    13081 gttcatggca tcgacgccca tgaaggcaaa taacaaaaag acgatccaga acagcacgcc
    13141 gctgacgacc agggataccg gtcggcgaac tcctgcctgg gagagcggct gaacaatgcc
    13201 caatcgttcg caaaacgaat cgaacccgaa ggtccggaga acccggagtg tgagcacttt
    13261 caccgaccag gcagccaaca gacccagact gagaaacgtt agcaaggcga ggagccgcgg
    13321 caacacgagc acgatctgca tcaccgtgtc acgaaaaccg gcgaccatcg tctctctcca
    13381 caggtcactc atcgcgccac ctccattgct ccacgaggta tggtttcgcc gcttcgaact
    13441 cgcggcatac tgtttccacc gtgcgctcca cctcgccggc atccccatgc tgagtttcta
    13501 aaacgaacga ggctgttcgt cccaggtaga gaggggtcag tgctttcagc atatgttccc
    13561 gatgcagcgt ctggttgtga tacgccaagg aaaaatcgta aacagtttgc acccagaggg
    13621 aagggggaaa gcggaactcc tctggatcct gtatgtcgag cgcgatgatc tgtcccacgg
    13681 tgtcccgaga taaaatcagc tcccagagtg gaagcaaatc gcgcaatccc tgtttgaacc
    13741 cactgatcat ccgtccggtg tgcagcgggc cgggatcggg tgccgactcc ggctcgccgt
    13801 agagcggcac ttcactggac gccttaattg cctcccacga cgactcgtac gcttccatcg
    13861 aatggaagat gcctccaacg ctctgggcga tcagcaccga cagatcaacg gcgccaagtg
    13921 tgctctcctg atctctggtg ccgagacagg tatggcacac acgatacccg ccggcgagcg
    13981 cggccgtcgt cagccggcta tccacactgt atttcgcggc aggccctttc catgtcggct
    14041 ggctaatcac gtcaccggcg aatttcccgg agagggcgta tgctccgccg ctcgggtacc
    14101 gtaatcgttt gccgtacagc gcacgggtca gggggtacag cagattggtc gcgagtgtcc
    14161 cctcataccg atggcgacga tatagtggaa ccacatagtc ttcgccctgt tcgtagaccg
    14221 gcctgccgag atggtcgatc cagcttgggc tcagcgagcg cagctgtccc tccagaatca
    14281 ggcatatctt tggtcggagg cgctgggctg tcaggcagaa gttatggatg ctttcgtctc
    14341 gccctggaaa gccaggttct ctcgtgagat gggcgtagct cccagtcgca ttggacacga
    14401 tgcggaccgg aatcacgccg tctgccagcc gggtgatgag gcctggagtg tcgtcttgtg
    14461 aacccgcatc gcaattcacg agcagcgcag acgcatgggg gaagaattgc cgcatccctt
    14521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn gcatcgcaat tcacgagcag
    14641 cgcagacgca tgggggaaga attgccgcat cccttccaca atcgatttca ggacaggctc
    14701 gatggatccg gcattgttga gggtcaagag gccgatcatg atgtcaatag tgtccgtcgg
    14761 ccactccatg tcggttctcg acacgctcag ctctgggctg ggtgccagca cctccgtctc
    14821 actcttcccg ccttgcggct tcgacatgac ggtggtcatg aagtctccat ccctctcacg
    14881 ctgccggtag gagtttgagt agggtgaggt aatcacccag ctgccgggta atcaggaaat
    14941 tgcgccgtac atgttctcgc gccatggccc ccatcctgtt catcaggccg ggattgttga
    15001 gcaaatgccg gatacggaat gccgcgccct ctacggaatg gaccacatac cccgtaacgc
    15061 cgtccacgat ctgggcggca ataccgccgg cggtgctgcc gacgaccggt ttgcctttcc
    15121 acatcgcttc cgacacggtt aacccaaacc cttctttgac ggatttttgc aagaccaccg
    15181 tggcactccg ctgcagcgca ttgatctcca gatccgcttc cgggggaagt tgaatgacat
    15241 gaatgtcggg atcgcgtgcc ccggcctccc ggagctccat gaggaccgct tcgccctccg
    15301 gatcgtgcat gaccccggac cccgccaaca cgagctggca atcatgatga cgcttgacga
    15361 gttggtaggt gtgaatcgca cccaacggat ccttgaagcg gtcaaatcgt gccacttgca
    15421 agatcgttgg tttcacccgg ggaatggcga gtcgatccag cacctgcgcg atctccgatc
    15481 ggctcatgtc acggtttttc ggactcagcg gatcgatgga cggataaatg agaaactttg
    15541 ggatcggtag tcgttgggca aatccggaca gcgagaaaat ggcggcatca tatttgagga
    15601 cgtaacgccg aagaaacgcc caggccggac gttgaggctg ggcgaggtcc aagtggcagc
    15661 gccacaacca gcagccattg gtccgatagt cgaccagtcc cgccggttga tggtcgtgaa
    15721 ccatcaccat gtcggcttcg agtttcagcg ccttggcatt tcgctcgatg acattcgcat
    15781 aggtctggta catgtcgtca gtcagcttgt cgtctcggcc ctgtaaggcg ttcagcatgc
    15841 gcgtgaccac cacaaagtac tcttgtgatc cggccaggac ttcccatcgg gcctcaacgc
    15901 ccaacgacac catcatcggc acgagtcgcc gcaacacctc tgacatcccg cctccatacc
    15961 tgacggcatt cagatgcagg aaactcttgc cttgtacgag gtcgctcagc cggtagagaa
    16021 aatccaccgt ccctttcggt gatacctcac gatattcgtc caatgccgaa tgcactcgat
    16081 ccttctcctt acgtggcgtg agatcccggg cgattcatgt tcgtcaaatt gcgctccatt
    16141 ccatgctgta ggcggttgtc ggcgaccgca cggccggcaa gtgcaaccaa tacgagctat
    16201 agggcccgag ggtcagcaca tacgggtgct cgtgaatggt ggggaagcgt gactcaccga
    16261 gcaattcttc gggcaccacg tctttgtagc gactgagatc cagctcaacg gcctgtgagg
    16321 atcccgccag gttatgcacg agcagcaagg tttcctgttc ataggcacga atgtacgcga
    16381 ggactttttc attggccgga ctgaggaact gcaacgttcc gcgcccaaac accttatgct
    16441 tcttccggat cgcgatcatg cggcgcatcc aattaagtaa cgaatgggtg gcttgtttct
    16501 gcgcgtcgat gttgacggcc tgataaccgt agacggcatc cgcgacgaca ggaagaaaca
    16561 attgcgacgg gtcggccttg gaaaagccgg cattacgatc ggcggtccaa tgcatcgggg
    16621 tgcgcacgcc gttcctgtcg ccaaggtgaa tgttgtcgcc catcccgatt tcatctccgt
    16681 aataaatgat gggactgccg ggaagggtga agacgatact gttcaaaagc tcgaccttgc
    16741 ggcgatcgtt atccagcagc ggagccaggc ggcgggcaat cccgatattg cgacgcatct
    16801 gcggatcgcg agcgtaggcg taatacatat agtcgcgctc ttcgccggta cacatttcca
    16861 atgtcagctc atcatggttc cgtagaaaga ggcaccattg gcaggctgat ggaatgtccg
    16921 gcgtatgttt gaacatgtcg acgatcggct gccgatcctc gctccgaacg cccatgaaca
    16981 agcggggcat caacggaaaa tggaaggcca tgtggaattc atcgccgtcc ccgaagtagg
    17041 ggcgcacgtc gctgggccat tgattggcct cggccaataa gacccggcct ttgtatcgct
    17101 gatcgatgct gctgcggatg tctttcaggt actgatgggt ttccggcaga ttttcgcaga
    17161 tggtgtcttc gcgctcgaag aggtagggca ctgcatcaca tcgaaacccg tcgaggccct
    17221 gatcgagcca atactccatg acctggatca tggcccggcg cacctcgggg ttgtcgtagt
    17281 tcaggtccgg ctggtggctg aagaaccggt gccaaaagta ggcctgtgcc tcatggtccc
    17341 aggtccaatt ggatttttcc gtatcgacga aaataatccg tgcgcgagga tatttctgat
    17401 ccgtctcgct ccagacgtaa tagttgcggg tgggggcatc cggagaagct ttggctgcct
    17461 gaaaccaggc atgttggtcg gaggtgtggt tgagaatcag gtctacgatc acccgcatgc
    17521 cgcggcggtg cgcctcctcc agcaaacggc gaaaatcgtc tgtcgtgccg taggatgcgg
    17581 cgatgctgcg aaagtccgcg acatcgtatc catcgtcccg caagggcgag ggatagaagg
    17641 ggagcagcca caagcaatcc acaccgagcc attcgagata gtccagtttc tgaatcaagc
    17701 ctggaaaatc cccgactccg tcgtcgttgc catcgtagaa ggcgcggacg tggagttcat
    17761 aaaacacggc gtctttgtac caaagcggat cttgattcaa catggatcag ctctttgccg
    17821 actcgctggt caggaaatca tcacatgcgc tgatgagttt ggaacgcagc cgctccagac
    17881 tgccctggta gggattgatc gagcggatgc ggtcagccag attcgtcaat ttcagactgg
    17941 tgcggagcca ggccgaaaaa tcgttttcgg cccgtcgtaa tcgaaagtgc gcttcaaaca
    18001 tatggtagta gatgctgctc acatcgatgt ccgtcacgat gtcgcggaac tcctgcagcg
    18061 tgcgcgcctc gagaccgatg gggacttcaa ggatcctgga gcgcttgaaa tggaatggct
    18121 ggccgaacac caccctagga atgatggggc tgcgggaaag gtggtcgtcg atgatggaaa
    18181 tcagttcctc tcgcaagttt tccaaatccg ggtagtcgaa gggatcaagg accgcaagac
    18241 gctcgcccag cacgtgatcc ccgatttgca tgacgaccca ttgcgcaaag tcattgggat
    18301 aggtgccctc aatcagtcca tggcggagga aatagctgtg tgtgtggaaa tggatggagt
    18361 ccagcggcac ttcttcgatg agctccgcca gttccttttc atcgtccgcc tgatgcgcga
    18421 tactttcctg gagttcgctg cagccgataa aggcaaacgg ggcatctgct gtaaggacca
    18481 caatccagac tccttcagag agttcagccg taagtcacac gcatcccgcg tctctcggac
    18541 aacatctaat cctcaggatg cgtccctgat gggttcacta taaaacttcg gccgcgggat
    18601 ccttactagt gaaacaccta gatggagaga gacgaagtcc agcgacatac tggtctctga
    18661 ctgagtgggt atcgtgtaga tggagtgatc actcggccat ggctctcaga acagcatgcc
    18721 tcgttccgat tgatgagtca ttgaatgtac gatgcggcag gaacgcggta gggcgtcgtg
    18781 tcacaaagta caccagcgac gggcagccac tgtgccattt tgaatgtgaa gcgggacatc
    18841 tgttccattc tgatgaaacg tgccgatatt attttgcctg cgattgtctg ccgcgctatg
    18901 cgcggcaggg tcgctcacct gcgatgcccc agcagtaaag acgctcggtt tccgcgaggc
    18961 cttaaacgta cctgcctgac agcgaacaag acccttccac cacgctgata gacgcgattt
    19021 tcttcacaaa cttcagggtg tcgtgtaccg tacaagcatc gactccaacc ctggtgttcg
    19081 gagtgtggat gcgcgagtca gtgctggggc atccaaccct tggtctagcg tctacatgct
    19141 caatccctat ctattgtttt ggagtatcgg cctgctgttt tttgtcgccg aatggctcag
    19201 gccggcgaga aagattacct atcgtgccgt cttctggcgc gacctcctcg cgctgggcgc
    19261 gtataaccta tcgttcctgc tggtcgtgca ggtgaccgat cggattccgg ttccgcagta
    19321 tctccccgtt gccctgtata atctgcccac agccggaaaa ctcttgttgt tttacatcgt
    19381 cgaagacttc ggcctctatt gggtgcaccg tctcatgcac acgagggtgg tttggcccat
    19441 tcaccggtgg catcattcac cgacgtctct gtactggttg gcaggcatac gcaccacgat
    19501 cccgcatatc gccctcttca atgtgaccta tgtcgccgcg cttccgctcc tgcacgatgc
    19561 ctcaggctgg gcgttccagg tcatcatggt ggaacatatt gtgcgtaaca attggatgca
    19621 cgtgaatgtc acctggaagt cgtcctggtt ggaatgggtg ttcgtcaccc cccgctatca
    19681 tcacattcac cacagcagcg atccggcgca tcaagtcaaa aatctcggcg cgttgctcac
    19741 gatctgggac cggttattcg ggacctacta caatcccgac gatgtgactg gtgaattgaa
    19801 gtttggtttg agcgaacgtg tgaacccgat acggcttgtc atcggcgtct agcacgccta
    19861 ttcagcgcta gagagacctg ctcagacgac ggcacttctc cattacctga ccatccagcc
    19921 acgcccgtgg tcgagtctca cgaatctaaa caacgtgtgc tgtaggaagc tcgtggagcg
    19981 ggtgcgaggt tattgagcgc cgttctcgcc gatcacgacg aactgcttgc ggaacccgac
    20041 gactttggcg agatagtccc gggtctcttg gtaaggaagc ccgctgcgga gccggtcata
    20101 gagggtggat ggctgaaggc cgttgatctg ttgcagggcg gtacgctgat ctttggcaaa
    20161 cgttttgaac acgttgccgg cgccggtatt gtaggccgag atgacgcagt attcacgtga
    20221 caccatgtcc gtgacgtcgt ccaattgaga ataggtcaac acgttgagat acgcagtgcc
    20281 cagttcgatg ttattgtccg gatcaaaaag ataatcccgc gacggggctt tgtcttcccc
    20341 tttcgctttc cgatacgcat cccgccctcc gctggtgggc accagttgca tcaacccgta
    20401 ggcgggggcg gagctgacgg caaatggatt gaaattactc tctgtgcgga taatcgcaaa
    20461 cacgagactc ggactgatct ggtaccgctc tgcgaactgc gcgaccacgg tgcgatattt
    20521 ctcggcctgt ttgtgcgaga aattggtcac catggggatg ttgacgagat gtgcggtttt
    20581 ggcaccgttc tcctgctcga ctggccgggt cgtgcttttg gccaggagcg attccgcgaa
    20641 ttgttccgct tccgtcggcg tacgcaccgg cttgccggcc tgattcacga ccagaccaag
    20701 aagatacggt tccttatcgc cggtcagggt gatttctttg tccgaaaaca aatcgacgct
    20761 acgcggatcg ttgggagtta ggagcgtcgt gacgacggca ttcttcaggc ttgcacgcgg
    20821 atccttctcg tcgagcgtct cgatcagaat gttcccggca tcgaagtcca cgatcgcccg
    20881 gctgcgatag ttctgggtgt atttcacata cttcttctgc tcgggtaatt tgacttcctt
    20941 ggtgccccat ttcttgccga cctctcccgt caacgccgcc atcaatgctt ggaagtcgcg
    21001 ttgaatggct cgcagatctc gaagcaatgc ctgggggtct cggccgtact gctcgacccg
    21061 ttgccgagcg atatcggcag ggtccttccc gtggacgata tccagaacgg ttctgccggt
    21121 cgtgctgccg acagcccgct cggcagcgcc gagcatctta tcggtggttt cacagccgga
    21181 aaataacgtg gggacagcga gacttagcag caacagggac attcggcgag tgcgcatggc
    21241 gggagtatac agaaggtgtg gccgggagga aaagagaatt tccgaaaccg tcattattcg
    21301 catggacagg gcccgtttcc tccggtcggc catcgggcat aggccagtaa atccacgtgc
    21361 ttgacgcctg gttttggggg ccagtaccat accccatcgc cgggattccg ggatgaaagg
    21421 cggaggtatg gggaacggac tggtgggtat gaacacacgt gcttcagctg cggtatggtg
    21481 ctgggtaatt gtgctgttga tgacgttggc cccaagcccc ggccgcgcgg cccagacgcc
    21541 gaccgaggcc gtgcaggtca cgatgaagga tctgctctac ctgctgaccg aactcaagga
    21601 aaccagccga tccgctcagc gacagtggga aattgaacag gtggtgcgac gcgcctttaa
    21661 ttatgaagaa atggctgaac gggcgttagg ggaggggagc gaaaagacca cgattgccga
    21721 tcgccggcaa tttacccgac tctttgtgca ggtcctccgt gacgacttag ccgataagct
    21781 ccgcgattat tctcttcctc aggtggccta tctctccgaa caaggcgatg gcacgggaac
    21841 tcaggtgctc gtggcgcctg cggggcgaga ggtcgatacg aagatcgaat tttctgtcgt
    21901 ggagcggtcc gggcgttggc tgatcaatga cgtcagcatc gacggtgcca gtattgtggc
    21961 gacgtatcag acgcagttct cccgcatcct ccgcgaaggc tctttctccg accttatgga
    22021 attcctcaag cagaaagccg tggttgctta gatcagatct tccggacggc tgccctcata
    22081 tattcccacg attgtcctca tgcctcatcg gccgttgtca tcaacggcgt gactcctgct
    22141 catgccgaac ggatccctcg gcctccggcc gaattgccgc cagacattgt tcccggaata
    22201 ccgtgtcgct gcgcgagtta gtggtgcgcg tggaccttca gcaagccgta ctcataggcc
    22261 cgcaacagca gtttctggcg gctgttcaca tcgaacttcc cgaaaatact ggtgaggtga
    22321 tggcggacgg tgacgctgga aatacagagc cgttcggcaa tgtccttatt cgagagggcc
    22381 tggccaatca gatagacgat ctcccgttcc cgtccggtca atgcagtgtc gggagatgtc
    22441 gacgagaggc ttggcggaga atcatcgtcg atggatgatt ccgtgcagtg caatctgcgg
    22501 cgcgtccttc gttcatacag ggttgtggcg tctgggaggc cgcagacgtg gctgatggta
    22561 gcgagcaata ccaccgccgg ttgaatggtc aggacaatgc cgtctattcc ggaggaaact
    22621 gatcccacga tgtgggcctt gtcctcaatg ttgctgagaa gaatgatgcg tgtcttcggg
    22681 acggaggtct tcacggatcg aacgagttct ctgacatcca ggtcggtctc catttcgatg
    22741 acaagcacat ggggctgttc ccgggaaacg agggtttccg cctcatgtgc gccgttggcc
    22801 tcacctacca gctgtatatg ctgctgggcg gatagcgcgg cttggagacc gatgcggacc
    22861 agatggttct tggtaactat cgccaccgta atgggggcat ggcatgcgtg cagatcgctc
    22921 atggatggtt ccgtccgagg agaccttaga gcgatgacac ggcggggctt ttcgtcgctt
    22981 cgcgccggca atactcataa cagctggaaa gaatgaggtc gcccgagaaa cgcacggtgc
    23041 cacagacctg tcccataaga agggcccagt cggccacatg ggcggccaac tgggtcggag
    23101 gcattccctg ggtacgaaac agattaatgg ccaccgtcga gaggactatt ttgagatgtg
    23161 acagggaagg accgtaactg aacacatatt cgtgttgtcc tgtaaagagg agttgcaccc
    23221 ccgttctagc cttcatgcca cgatgaccgc agcggggaca aaagaggcat tcaagtccgc
    23281 tgtcggggtc atacccggcc cgaacatccg tttccatcat ttggccacaa tgggtcgcag
    23341 ggcacagcat catgataatc tccctgaaga ataatcggtg cattgcgcgg ttgtcgtctc
    23401 aggcgctatg gagcgcgtga gttcccgagc ggccggaacc ttctccgctt tgcggggccg
    23461 attctccctg gacgatccgt tccgcctcga gccaatcttc atagtcgtat ccgtcctgct
    23521 gtcctcgttg ctgatatctg gcatacgcca gcttttcgat cctggttctg atgtcctcgg
    23581 ctgtatccgt ggtctcggct tgcggcgacg gctggagtcg atcctttcgc ttgggaatcg
    23641 acctgctggt ggcccctcgg gagatgtttc gtatgggttc gtcgcctgca ggtgcctgtg
    23701 cgttacgttc tggcatgatg accactcctt gccgatcagg ccggccgctg agatgttatc
    23761 gatgaatctt gctttactga agtcgtacgc agggtatgcc gagcgtcgtc aggagcaccg
    23821 cttcgacggg gtgttccaga gggggactgg cggatttcgc tgagagcgta tcgccggatc
    23881 gggactctcc gctcaagacg ggatggaccg gctccgagag ggcaagaacg ggtgcctggg
    23941 gacagagggc gttaagggcg cggagtgcgt ccatccccgg agtgtcgcag tgggaaccgc
    24001 ctgaatcgtg actgaacagg atggctgccg gctgaatttc gccgagttgc gggagtgtgg
    24061 actcgaggtc tcgcacgagc accgcatgat accctctcgt tgccaggcaa tcggccaatt
    24121 tgagcccgaa ctgcatcgca gaatcgacga tcatgacgcg tgatcttccc gcttgcttga
    24181 cagggtgcat cgtgggactc atcgttggcc ctccttgttc atgatctggt caactgcggc
    24241 tacccccaaa gacggtttcc cggccgtgac ggggatgaga tggcgcaagg tgctcgatcc
    24301 cgatccggcg agggacaccg tgtactgaaa ttcaggcagg ggacgcagaa cgagcgtgcc
    24361 tcggcgggac aggatgtcca cggccatgaa tacctggttc caggtacagg tctggagttg
    24421 ctgcgccaag gcttccagcg tgcaggctcc gcgccgtgtg agttctcggg taatcaatcc
    24481 ctctatctca gccagcgtag tcatctgatc gttccttttc ggtactctcc tgatgtccgg
    24541 gcagggtcca attgtacggc cttcgctgct ccggccttcg ggggacgcag cagactcaat
    24601 gtgacgcgac agtgctaggt gtacctcttg agaggcaggc acgccatcgc cctttgcgca
    24661 aaatgcgcgt cgccgttctc ccagttctgg ctgtcgccgt ttatgctacg aattggagag
    24721 gagaggcagg aacaacgtct gaacggagtc aggacacgag acggttgacc agacgatttt
    24781 cgagggcgta atgggtcaat tcggtattgt tcttgaactg cattttttcg aggattcgcg
    24841 cacgataggt attgatggtg ctgatgccca cgcacaggtc atccgcgatc tccttgaggc
    24901 ttttcccgac cgcaattaaa cacatgactt ggtattcgcg gtcggagagc aactcgtgct
    24961 gcggtcttcc cgcctcctca ttgaggttgg cgacgagtag ttccgccatg gaggcgctca
    25021 caaatttccc gcctcccagg atcttcttga gcgcctggac caactcgttc ggggcactgt
    25081 ccttggtgag gtaccccgag gctcccgctt tgagcattcg ccgggccaac tgatcttcgg
    25141 ggtaggcgct gagcaccagg accggaagtt tcgggcagac ctgcttgagc tctttgagcg
    25201 catcgaggcc gctctttccc ggcatgccga cgtcgaggac cacgatatcc caggtgaatt
    25261 tccggatccg gtcgatcatc tcctctgcat tccgggcctc gccgatgacg gcgccctgga
    25321 attgctcgtt gaggatttgt ttgacgcctt gtcgaacgac cgcgtgatca tccacgacca
    25381 gaatttttgt cacgataggc tccatctgtt gcgtctggtc caagaatgga ccggtcatga
    25441 tgactcaaat ctgttcccgg cttactcctg agccggctgg tcaagcggga tcctgactcg
    25501 cacgattgtt cccgatccgg cattgcctgc gaacgtgatg ctgccgccga gcagtaaggc
    25561 gcgttcgcgc atgccgacca atcccaggga ctggggatcc gccaactcgg tttcggtgat
    25621 gccgcgcccg ttgtcttgca cttcaagcac cagcccgccg ccctgttcct ggagcgtgat
    25681 cttgacgacg gaggccttcg catggcgcac cacattggtc aggatttcct gaaaaatccg
    25741 aaacatcgcg gtcgatgcgg tctgcgatag gcacgcggac cgcagataga tatcgagtcg
    25801 gcattctatg ccggtgcgtg actgaaattc gtgcgtctgc cattcaatgg ccggaatcag
    25861 gccgagttga tcgaggacga tggggcgcag gtccgtggca attcgtcgca cggactggat
    25921 cgtggcgtcg acgagaccgg aaatggattc caggcgactg tgcacagtgg ggggcacact
    25981 ggggagctga tcctgcaaca aggagagttc aagtttgacg ccggtcaacg cctgcccgag
    26041 ttcatcatgg atctcgcgcg cgatgagaat ccgttcttct tcccgcaccg attccaggcg
    26101 ggcggtcagc tttctcagct gtgcatgcga ggcggtcagt tgctgctccg cccgtttgcg
    26161 gtcggtaatg tccagaaaga cgaccacggc gcctgtgacc ttcccctgtt caatcacggg
    26221 gaaggaggag tattccacgg ggaatgacgt tctgtccttg cgccagtaca cttcatcgtc
    26281 gaccttgcgg cctctcccat ccacaagcgt ttcgtggatg tggcaccgtg tccgatgata
    26341 gatgccgccg tccggcgagg agtgatggat ccgttcatgc atgtcttggc acagcagttc
    26401 atcgggcgaa taccctaaca tacgcgaggc ggcggaattg atgaacgtgc agcggccctg
    26461 tcgatcgagg ccatagatgc cttccccggt ggattccagc aggagaaggc gatctttggc
    26521 gagttgctgt cggatttctt ccgcccgctg tttatcggtg atgtcggtgg ctattccgca
    26581 gagcgcgtaa cagcggccct ctgcgttgcg caaaggaaac ttgaccacaa tgctggtgtg
    26641 tgggccgtcg tcatgcaacg ctgattcttc gaattgcatc ggggcgtcgg cttgaagcac
    26701 cttccggtcg ttctcgcgaa agaccgccgc ttgagccggc gcaaaaattt cctcatcggt
    26761 tttcccgacg agatccttgt tcgccaggtg ggacaccgtt tcgaattgcc ggttggcttg
    26821 gaggtagcgt ccttctaaat ctttgagaaa gatcagggcg ggactgttgt ccataatggc
    26881 ccgaaagcgg ttttcgctgt ccctgagcgc ttcatcggtg cgcctggctt cggtgatgtc
    26941 gcgaaagacc accacgccgc ctttgatcag gcccatctca tcccgcaggg gcctggcgga
    27001 cacatccagc cagaggtcgt taccctgact ccggcgtttg agaaacaggg tcgagccggt
    27061 cacggattcc ccccggatgg cccgtgcgag cggaatatcc tccgcggggt aaggggtcac
    27121 gcggtcagga cgaaagatgg tgaagtcctc ggaccaatgg ccgactgttc gtttggccgg
    27181 gccacttccc aagatctgtt ctgcggcggg attccagacc cgaaaggtgc cggtttcatc
    27241 ggccatcacc acgccgtcag ccatgctatt gagtaccgat tggaggaagc gtgtctgctc
    27301 gcgcagttct tcctccagcc gcttgcggcc cacggcatat ctcagcgcgc gtgcgaggag
    27361 aggggccgag gtctgtcctt tgatcagata gtcttgcgcg ccggcttgaa tgaggtggag
    27421 gcctaactct tcatcctcca agccggtcat cagcacgatc ggaatcccat gtgcggcggc
    27481 atgcattctg atcagggttt caatgccctg gctgtcgggc aaagacagat cgaggagaat
    27541 gacatcgatg agggactcgc tcagacatcg gattcccgca tcgagacggc cgacgtgcgt
    27601 aagggtgaac tgtccattgc cggtttgtgc aaagagctca cgcaccaggc gaatgtcgcc
    27661 cggattgtct tcgatcagca ggacatggat aggccggttg gtcataccgc tcccggttga
    27721 tgtgagaccg gcagcaccac gatgcccagc cagaaatctt cgatcgatcg cacgacccgc
    27781 acgaactggt ccaggtcgac cggcttcgtg atgtagcagt tcgcatgaag attataactc
    27841 ttgaggacat cctgttcgtc ttgagaggta gtgagcacga ccactggaat gcgcttcagg
    27901 ctgtcatcgg ccttgatatc ggcgagcacc tcgcggccgt ccttcctcgg caggtttaaa
    27961 tcgagcacga tgaggtgagg gcggggggcg gcggtgtagg aaccctgccg ccgcagaaag
    28021 gccaaggctt ccatcccgtc cttgacgacc gtcagatgat tgatcacctt ggcctctttc
    28081 aaggcctcga tggtcaaacg aacatctccg ggattgtctt ctaccagaag aatttcaatc
    28141 ggctttacca gttctggcac gaccatcgtg atggctcctt tggattgtgg acgtgaatca
    28201 tgcaacgcct gttgtcgcgc cttctgagcg agtgacggag ggttgctgcg gagggtcggg
    28261 aatgctgaac cagaaggtcg cccctttccc cgtttcagac tccacccaca tgcgaccccc
    28321 atgacgttcg acaatctttt tgcagatggc cagaccgatg ccggttccgg ggtattccgc
    28381 cctggtatgg agtcgctgga aaatgacaaa aatccggccg gcaaattgcg gatctatgcc
    28441 gattccttcg tcgcgtaccg aaaagagcca ctcatcttct ctccgctggg cggatatgtg
    28501 gatgcgcggc ggctggtccc cgtggaactt aatggcgttg ctcagaagat tctgaaacag
    28561 ctgcgccaac tgtttggcat cgcctctgac cgtcggcagc cggtcgtggg taatgaccgc
    28621 ctggctttct ttgatggcgc tcaggagatt gtccatcgca taggagagca cggctcccat
    28681 tggtgtaggc tcaaacggct ggctgcctgt gctgacccga gaataggcga gcaggtcctg
    28741 aatcagcttc tgcatacggg tggcgccatc gacggcatag gcgatgaatt catccgcgtc
    28801 ggcgtccaac tggcctcgat accgcttcgc caggagttgg gtataactgc tcaccattcg
    28861 cagcggctcc tgcagatcgt gtgacgccac ataggcaaat tgttggaggt cggcgttgga
    28921 gcgtcccagt tctgccacag atttttcaag gtcctgtcgc gttttcagga gttcggatcg
    28981 ctcgcgtccc aatttccacg aaaccaggat gccgaatccc gtcaggggta ggatgacgag
    29041 caatccgatg ccgccgaccg tccacagtag ccgatcgaca ggcgcataga cctggtcatg
    29101 cgtctgacgg aacagcacaa tccaatcaaa tcctggaaaa tcccgatagc ctctggtcga
    29161 ggcatacccg gtgacgacgg agtgcccctg gcgatgatgg acttcttcga caaatcctga
    29221 ttgattccgg tcggaggctg cccgggatcg agagggaatg tctaagatcg ctgatccctt
    29281 ggggctctcc gctgaggtct gtttttcgct gatgatggcc ccgtcccgag tgagcagcaa
    29341 ccaatcatag gggtctttgc cgtaccgtag tctgccttcc tgttcgaaaa tcgagcgaag
    29401 attgtcgatg gggacgcggc tggccaccac tccacgaaat tcacctcgcg gaccgtagat
    29461 cggtgccatg aatcccactg ctttctgctg tgggggcatg gcagaaggga ccaccggttc
    29521 taggtaaatg gtgcctgacc gccgaacggc atcaaaggct gcacggttga gagggggggg
    29581 gcctgacgca ggacgcatgt cggtggccgc gatgaccgtt ccgtcggcat cggtgattcc
    29641 cagccagctg tagtaccagt agagctggtg gtaatgctgc agccgggcgg tcctctcttc
    29701 ggatgaaccg tcccggatca cgccatcgtt ggcaaacaac tggatatcgc cataccgctc
    29761 gaacaacacg cgatcgactg tctccgccac ggtcgcagca ttcatggcga gttcgtctcc
    29821 tcgttctgcg accagcatgg cacgcaggaa ggagagggcg tataacccga gggcggtcgc
    29881 gatgaaaaag cacagaaaga ggaggatcgg caggatgcgt tccgtccacc ggctgctact
    29941 atcgaatgct gtggtctgca cggttgttgt cgggagcgca atcatgtcag gtgattagag
    30001 ggtaaagcct taatagttta acctgttcgg ataggcagtt gcacgaggaa gccggtgagc
    30061 atccattcat ggctgcgttc gattgactcc gcgccggcgt ccgggtacgt tcagaccact
    30121 ctaggcgcgc aaaggacagg atgttgagca tttcgacaca tgtctcgatt ccggatgagg
    30181 agatcgagtt gacggcagtg cgggcgcaag gcgccggcgg gcaacacgtc aataaagtct
    30241 cgtccgccat tcacctccgg tttgacgtca gggcgtcctc cctgcccccg ttttacaaag
    30301 aacgtgtgtt ggagctgcgg gaccatcgtg tgtcgcgtga cggggtcatc atcatcaaag
    30361 cacaggactc gcggagccag gagcggaacc gtgcattggc gttggaacgg ctccgggagt
    30421 tgatccaaca ggcggcgatt ccgcggatac cgcgtcgacc taccaaaccg acgaaaggct
    30481 ctaagaaaag acggctggag gataaatcga aacgcggcca gctcaaaagt ttgcgaagcc
    30541 ggcctcatga gcagtgaggc gcaggaagaa aaaaaggggc gcttcgggtg aagcgcccct
    30601 tccaggacga gacgaacctc gtcaccaatt agaagcggtt gcgtccgccg cggtcaccgc
    30661 cgccgaaccg tccacccccg ccgccaccgg agcgaggctc ttgcggcttc gcttcattga
    30721 cggtgagttg ccggccatcc atgtcggagc cgttcaacgc cgtgatggct gccttggctt
    30781 cttccgccgt ggacatttcc acgaagccga agccgcgtga ttgtcccgtg aacttgtccg
    30841 tgatcacgcg cgccgattca acggtgccat gagcggagaa caagttgctc agttgcgatt
    30901 cagtggcagc atacggcagt ccgccgacat acaatttgtt acccataggg gtctcctttt
    30961 gaaatgtgac attgtcggcg acacgagaac aggcatatga ggggaatgag cgggccgaag
    31021 gcgcggtggt aggggcgact tgggtctgac ttccgatcaa cttctcggta acaaacaata
    31081 tcggtgatga gccatcaaca cactgtgatt ctcatgcggc ccgtcataag atcactctgc
    31141 atcgtaacag atgaagcagg ggattactac cggtttcagg gctgtccaaa aaatactttg
    31201 aggcgcggca gagagctgca accgtagcca gacccggttc taattgcctg gggacgcggt
    31261 acggagcgat gaggccaagc ctaacttcga cagggtatag atcagccact tcgacgggtc
    31321 aaaattgtac cacagcggtc cattgcgata gtcgctcggg taggtgtggt ggtaattgtg
    31381 gtacccctcc ccgaaggtca gcaaggagac gagccatgag ttgcggctcg aatcggaggt
    31441 gccatacggc tgctcacccc agatgtggca gaccgagttg atgcagaagg tggaattcag
    31501 gaccgcaaag gtgcgtccga cgccggccag cataaatcct ccgattccac cctgccatcc
    31561 gttatggagg aagccgatga cgaaggggag ggccaggccc acgacgacga tggccgcata
    31621 attgcggtgt tgccacatgg ccaccggatc ctgcatcacg cgggagccga atcgttcatc
    31681 gttgcagggc acgggattga ggagccagcc gcaatggcta taccagaatc cccgcttggc
    31741 attgtacgga tcagcgggat cgtcacaatg ggcatgatga cgcaaatgat cggccgtcca
    31801 tttcgcgccg gagttttgca aggcccaccc accggcgacc agcaggcagg ccttgaccca
    31861 atcgggacat tcaaagctgc gatgcgtcaa caggcgatgg tatcccacgg taattcccag
    31921 gccggtgatc aggtagagga cggcgaacat cgtccaatcc agccaggaat agccatacag
    31981 gattccgtac ccgggcacgc aaatcaccga gcctgcgaca atcgaccaga agagaaggta
    32041 ggtccagaac ttatgatgca cgcggtggac gatgtgtgcc ggaacggggg tcggggaaac
    32101 ttgttgcatg tcgctacaat agtgaagcag acggtttttc gcaagaggcg atgcgcgatg
    32161 accggagagt gggggcggtg cgcagatctg ttcggtgagg gcgtggcgtc aaccgtctgc
    32221 cgctcgccgc gttgaatcct gtgggtagag gaacatttac gttgaggcca tccacggccc
    32281 ggacaaggat ggtgtcacca acagagaagg aggacagtat gcctactggg tatccacgaa
    32341 aggcgacatc gatggtgctc tggagttgtg tcgtgatcgg attgtctggt ctgtatgcac
    32401 cggtgaacgc cgcaccggat cctgcctcca cgggtcagga acagccggcg gcgacttccg
    32461 aagagcccgg cagcagcggg aagcgaccgg aggggcaggg gcggggaggt cgtccaggca
    32521 ggaaggcttg tgccgatgac gtgaagaaat tgtgtgcggg ggtcaaagcc ggagaggggc
    32581 ggatcatgca atgcctgaga gagcacacgc aagagctctc tccggcttgc gccgacatga
    32641 tgcaacaacg aggaaagcat cggccgtaac ccttgtatgg cattgccgcc gggcggcgcg
    32701 atgagccgcc cggtcgaccg ttctcacggt tcacgcctct ccctctccat gcctgtcgtg
    32761 tgatttcgat attttattct cgaagtgctg cgagtgcgat acagtaccct tgatagatac
    32821 gggagggtac gtatgagtga tactactcgt caggaacagt tttcggtcga cttgcgtcag
    32881 cacccgcgct tgcgtgtgcc ggcgccgttt gcctgttcgt tatcccgatt gggcctggcc
    32941 aagtggctcg gtcgcggagg cgaggggatc ggtgtcgtct ttgacgtatc gatgcgaggg
    33001 gccaaggtga tgagcgaagc aggaatccag cgcggcgatc gagtatcggt cagtctgtca
    33061 cttcccaatc aggtctcgcc gatgacggtc gagaaagcca cggtgcggtg ggagcgggag
    33121 caggtctacg gcttggaatt tgtcgacctg tcgccggtgg ctgaaatgcg tttgcgaaag
    33181 ttcatctccc tggcgacaaa gccggcagcc tgaggcttcg gtgcggctcg cgatttcttc
    33241 cgcctggtag agcagcctcg atacggtcga tccttcgaac ttggtgccac gttccagaag
    33301 acgggggtat ctgctcgacc cctttcccct ctccttcgac attgcgctcc tcgctccgtt
    33361 tccctacaat gactgacccg tttggccatg tcgaaccctc aggcaaacca taagcggcgc
    33421 cagccacgta gtgtctatca tccgatgtat tggcccacgt gggtcggcat tacgctcttt
    33481 cgactgctct cctggcttcc ctatcatgct cagcttgcgt ttgggcgtca gtgtggacgc
    33541 ctgttgcacg ggctgctcac gaagcgccgg gacatcgtcc gcgtgaatct cgccctctgt
    33601 tttcccgaac agtcgccgga ggagcgcaat agggtggcgc tgcactcgtt cgaatccatg
    33661 ggaatgggtg tattggaaat cgccatggcc tggtgggcga aagatccccg ggcgcattgc
    33721 gaatgcacga tcaagggctt ggagcatatc cgcgacgcgc tccatcgcgg gcggggcgtg
    33781 ctgctctgcg gggcacattt gcatgcggcg gaactagccg gtcgattcat ggcgctggag
    33841 cagccggtcg ccatcgtgta tcggccgcag aatgatgtcg tggccgatat ggtcgcgaac
    33901 cgctgccgga gccgatatta ttcagaactg attcaacatc gggatatgcg gggcatcctt
    33961 cgcgcattag ccaggaacca ggtggtctgg tacgcgcccg acatcgatgc cggatcgaag
    34021 cgtagtgtgt ttgctccatt cttcggcgtg ccggcctctt cgctgacggc gacgtctcgc
    34081 ctggccaagg tcagtggtgc cgcggtcgtc ccctgctttt attatcggcg ggcggatggg
    34141 tccgggtatg acatcgaggt aggggaagct ctggaccatt ttccgtccgg cgaaatgatc
    34201 gaggatgcga cccgtgtcaa ccggttgatc gaaggggctg tccgtcgcgt gcctgaacaa
    34261 tatttctggc agcatcgccg cttcaaaagc cgtcctcccg gcgaaccgcc gctgtatcgg
    34321 cgatagccgc catccccggt acgcgggttt ttctcactgc ctcatcagtc gccgtggtca
    34381 gcgaaatcat cagaaatatt cggcgtttcg cgccccctgg ggtatactga cgttggctgt
    34441 tttcagacga cgactgcacc atccgctccg ccatggatca agataaacag gtctctcccg
    34501 ttcgcattga gctccggcaa catcgtcgct gcccggtggc cgagacctgc ctgctgtcat
    34561 ttgccccctt cgcaccaacc ttgagtttca atggcgatgc ggaaggtgaa gggacggttc
    34621 tcaatctgtc gcccggcggt tgcaaaatca gcagcgaggc cggagtgaag gtgggcgatg
    34681 ccatgtcgct gattattctc cttcctggag agactgctcc tacggcggtc gatctggcgt
    34741 tggtgcgatg gggcaaggat ttgtcttttg gtgtggaatt cgtctcgatg ggcacagctg
    34801 aacaggatcg attgcgccaa tttctcgcct ccgccgctgt ctcggagtaa ggtgataccg
    34861 acgtggatat ggtgcgcgtg acgaagagga gtgcaggtgg aagaaacaag aaccttgcgt
    34921 aagtcccggc gcgtcgcggc ggattgtcgt ctcgagttcg tcggcgaaga tgagattgaa
    34981 ggagaggccg aggtgctgga cctctcgtcg accggatgca tggcaaaatc cgaccaggcg
    35041 atgccgccgg gccttcgcat gaaagtctcc ttattgttgc ccgacggaca tgaatggccg
    35101 gttcgcatag aggaagccgt ggtccggtgg gcccggggcg gagagttcgg ggtggaattc
    35161 ctggtgatgc ggcctccgca actccagcgc atccagcagt tcgtgatcaa gcatagaccc
    35221 ctgggttaag tcgcgatcga cacctgaccc tctctgtccc ttgcccggtt gccccccagc
    35281 gattcgtgcc tttccgccct gagcctgcca ctcccgtttc cccactcgtt gctttacgat
    35341 gactgcttcc ctacaatttc gccgtcgatc gcggcttcag gcgcccgaca tgctccttac
    35401 acgcgaggcg attcagaaga catgttcacg tgggtcggac ggaagaccat cgcggggtac
    35461 gcctatctgg cggcgttggc gacgctgttt gcgcaagccg tttttgatct gatcattccc
    35521 ccgaagcagg ggcgggggga gaccttccgg gtgttggtca ggcagattct tttcacggga
    35581 gtcgacgccc tgccggtcac gacagtcatc gccctgttgc tcggcatcat cattgtgact
    35641 caggccggta cgcagcttcc caggctcggg gcaggggggc tggtgggcag catcatcgtg
    35701 gtcaccgtga tccgagaact cggccccctg gtcacagcat ttattgtggt tgggcgttcc
    35761 gggtcggcca ttgccactga gctcgggaac atgtcggtga cacgcgaggt ggtcgcctta
    35821 cggctcatgg ggatccccat cagccggttt gtcatcatgc ctcgtatggt cggcatggtg
    35881 ctctcgatgg tgtgcctgac actgtatttc gatgtggtgg cggtcttcgg gggctacctc
    35941 gtggctgatg cgcaattgac cattccgctc gatgcattcg cggagagtgt catcagggcc
    36001 ttgtccacga cggacgtcct tatgacggcg atcaagggcc tgggctttgg ctcggcggtt
    36061 gcggcggtct gttgttacca tggcctggct gtccgatcgt cctatacgga ggtgccgcaa
    36121 caaacaaccc gcgcgatgat caactctttc gtcctgtgtc tgctgatcga tgtcgtcgtg
    36181 acggtaccgt tgtatctatg agcgaggcag ccattatttt cgacaaaatc cgcgcgccca
    36241 tgttgggcgg agacctatgg ctggaactcg atctcaaaat tatggcgggg gagtgcgtcg
    36301 tctgtgtggg gccgagtcgt gccgggaaga gtttgatggt ggagcttgcc gccggactga
    36361 ttgctccgga atcggggcgg gttcttgtgt tgggccaggg ttggagcgag gtttcggacg
    36421 atgctccggg gtccgtacgg ctcaaggtcg gagtggtgct ccaacagccg gggttgttga
    36481 gcaatatgac gctctttaac aatgtgctgc tgccgctgcg ctatcatcga agtgccatgc
    36541 cggatcgtca ccgtgaacaa gtggtgatgg gagagttgga gcgattaggt ctggcctcgc
    36601 tgcgtgatcg gtttcctgcg gagctgaatc agggggaggc ccggcgggga gccattgccc
    36661 gagccctgat attggagccg gaggtgctcc tcctcgatga tcccgtcgcc ggcttagacg
    36721 ctgacatggt gttgggactc aagagctcta tcgacgaacg gcgggcccag cggcccctca
    36781 cggtcctcgc ggcgttgcgc acctgctcgc cattcgttga tgccgccgat cgcttgattg
    36841 ttcttcgcga tggccatgtg gaagcggacg gaacccgtga cacggtgcgt gacctggccc
    36901 ccgaagcgtt gcggaggtat gtagaatagc cgtgcgatat ggtcggatag agaggtgagt
    36961 gatgatgcac tattcgcatc gtctgtctag cgggcggctg gcgcagatcg tgggcacgtt
    37021 tgtgctgatc cccgcggtga ttcttgccgt ggctggtttt tggatgtcga ggacggaaca
    37081 cctgttcgag tcaaaatatc tgctcaaggc cagcttgagt aagtcttacg gcctcgagcc
    37141 gggggcgccc atcgtcgtat ccgggattcg catcgggcgc gtcaagcagg tggacctcaa
    37201 tgatcgaggg accgtcgatc tgacgcttca gctcttggcg cggtatcagg atatggtgaa
    37261 ggagaattcc gagctgcaca tcaccaagag tggtgtggtg gtgggccaga cgcaagtcga
    37321 catcgccatg ggcacggcca gcagcccggt attgtccgag ggctccatca tccgtgccgt
    37381 cgaaccgcgg gacatcggag acttgctcaa tgaggtcgag ccggtactga tggccgtgaa
    37441 gcaaacgctg ctgcgggtag aaaccatcac gcaggatatg cagggtggcc tgaaggccgg
    37501 tgggaaagcg cttgaacagg ttgccctggc aacgcaggag ctgccggcag tcgtcgcctc
    37561 ggtacagcgg acgattgcct ccgtggaaca gacggccacg gcgctgcccg ccatgaccgg
    37621 atccattaag cggacgctga gcatggtcga tcgcgtcacg gccgatgtcc aacagacgac
    37681 cggacggctt ccggccattc tcgacagcgc ccaaacgacg ctcaccagcg tcaagcgact
    37741 ctccgattcc gtgagtgaag tgagtcagga gctgggcccc atcatccaca gcgccgagac
    37801 cacgttggcg gatatgtcga ttctggtgcg tggagccaag cagacatttc ctttcaatcg
    37861 gtttgtgcag aatgccgggc cggcgcccaa ggagtcaccg ccaccctcgc gggaagggac
    37921 tcaaagtttg agaggagatc agttgcgtcg atgagagtgc ccacaccagc ttcaggagcc
    37981 acatgctgcg cggtggcatt gtgtctgctg tcgggatgcg cgagcccccc gccgcccccc
    38041 tctcctgcgc cactgcccag accattggcc gagcagggtg aatcgttgcg gcgtcaaggt
    38101 gaccgttcgt tcatgcgagg tgatctgact cgcgccgctg aagagtatga ggcggcgcgc
    38161 cggatggcgg aaagcctgga tgatacgcag gggcttatcg tcgcgatcaa tgatgtcggg
    38221 cgcgtggctc tcaggcgcgg ggacgttccc cgggcggtca gttcgcatga gcgagctgtg
    38281 gccttggcgc aacaacgggg agagccggat cttctgattg ccagtctgac tgacttggcc
    38341 actgcggaac atcaatcggg tgcactccag gaggcagaac atcgatacga acaagcgtta
    38401 gacctggctc agcagcgagg cgatcgttcg gctgaagcga caatccgtaa caatctcggg
    38461 ttgatacggc aggccaaggg cgacgtggag caggccgcgc aactgttccg tcaggccctg
    38521 gccttgaatc aagcactggg aaatttggaa tccgaggcca gcaaccatgt caacctcggc
    38581 atgttggccg aagcacggca tgagtatgac gcggccgaac gggaatatga gcgagccctg
    38641 gagttagaca aaacggcgga gcagcggatg gagattgcgg cggatctctt gcggctgggg
    38701 aagattgcgg atcgacgagg atttcccgat cgaggccaga cgtattcgga gcgggcttac
    38761 caaagctacc tggcacaaga tgcatttgcc gaggcccggt cggcgctgag tcaggctgtg
    38821 gcttgcgcga agaaactgga gcgggccgga gacattgcgc ggttggaacg ggaattgacc
    38881 cgtctgaccg cggtgcatcc cgcacggtag ccggttcccc tggcgtaccg ccgcatgctt
    38941 acttgatggc gacggctttg acttctttat acgtcgtgtg tccctgcagg actttctgaa
    39001 tgccgtcctg aaccagggtc gtcatcccgt cttccatgcc ggcatgcagc atctcatcgg
    39061 tcttcgcttt attctgaatc aacttcttca tcttgtcggt acccaagagt aactcatgca
    39121 acgccacgcg gcctttcagg ccggtgcgat tgcaggcgtc gcatcctttg ccgcgataga
    39181 gacggaagtt cgcgtcgaac ggcactttga gggcgtccca atagtcaggg ccgtacccca
    39241 aacgcagctc ctcatactct tccttcgaag gctgataggc ctccttgcag tctttgcaga
    39301 tgcgccgggc caaccgttga gccagtacgc ccagcatggc gtcggcgaaa ctgaatgagt
    39361 cgcagcccat gtccagcaat cgggtgatgg tttccaccgc gctattggtg tgcaacgtgc
    39421 tgagcaccaa gtgacctgtc aatgaggctt caatgccggt gtctgccgtt tctttatccc
    39481 gcatttcgcc gaccataatg acgtccggat cggcgcgaag gaaggcgcgc atagccgccg
    39541 cgaaggtgaa tccgattttg gcatgcacct ggacctggcg caggccgtac tgcgtgattt
    39601 cgaccgggtc ttctgcggtc cagatcttga tgtccggcgt attgatgtag ccgagtactg
    39661 agtgcaacgt ggtcgtcttt ccggaaccgg tgggacccac gcagagaatg atgccgtagg
    39721 gtttctcggc gatgcttttg atctcgcgca gattacgttc cgaaaagccc attttatcga
    39781 ccggcagcgg ctcgctggcg gccaggatac gcatgacgac gtcttcgtta tagccggcag
    39841 tcgggatggt ggcgacgcgc agctcgattt ccttgttttc gccgatttta aatttgatct
    39901 ttccgtcctg cggcttacgc cgctccgcga tgtcgaggct ggccatgatc ttcaggcgcg
    39961 acacgatggc acggcgatag ctcggtggaa ttttcatgta ctcgaagcag tcgccgtcga
    40021 cccggaaccg gacgagggtg tcgcgttttt caccgtaggg ttcgatgtga atgtcggagg
    40081 tgccttgccg gaacgcatcg gcaatgattt ggttcgccag gcggacgatg gcattatcgt
    40141 tttcgtcgag tcccgcggcg gaggcttctt cctgggcttc gagctgggat tcgttgacca
    40201 gttcgccgag aatgtcggac acattctcgt tcatcttgtt ggtgacgtcg ggggttccgg
    40261 tcgtgcttgc caggaagagc gagatgtcgc ggcgcagact gacggcaaac cggatgttga
    40321 gccccgggaa ggtgcgcttg atgtcttgaa cgcggtcgag atcgccggga tcgtccgtga
    40381 gaatctcaat ggcggcgcga tcccgcttga gcggcatcca gtgattcttc ttcaggtagt
    40441 cgacgttgag gttcttgagc aattcgatgt cgacgatcgt gcgctcgttg tattcgatat
    40501 aggggcactt gtggaaattg gcgagtgatt tgccgatctc agctttcggg atcttgtatt
    40561 tctcaatgag cagcgactcg atatccgtcg tgcccttttt tgcctcagcg agtgcgacat
    40621 cgagatcgtg ttgggaaatt tttccattgg tgagcaggta gtcgtatttg gacggcggct
    40681 ttttcgaggt ctttcgaagg gtgtagaacg cggtgcccag ggatttggca atctccgcga
    40741 cgcactcttc gtctttgcgc gtgaagcgtc cgccgctctt tttgttcagg agttgaatca
    40801 cccccatcag atacttgttt tcggcgacga ccggatacgc gagaacttgt ttggttttga
    40861 agccggtact tttatcgtac gtggcatcgt gggtcagcga cggatgaatc gcgctcagtt
    40921 cgaccaagct gtaggcatca ccgacattga ccgggcgcag gtatttggcg caaaaccccg
    40981 ccaggctttg ctcagtgatc ggcgtacgca cttcctggac ggtatcgaga tgaggaatct
    41041 tggagaagat ttcttttttc tcggaatcca cgacgaagag ggtgaggtct tctgcgtcga
    41101 aacatccgag gatttcgtgg cgtagatcca ggagaatttg atcgacgtct gcggcggcga
    41161 ggatttgtcc gctgatccgc ttgacctgtt cggcgttccc ggatttgaga gtggcatcgc
    41221 cactaggcag cggagcttta ggctgcatca acgtgtctcc acgcgggctg aacggggaat
    41281 tgcatgcagg gtcagaaacg cgatgccggc ctggaatcgt tcgccgtaca ggagtttcgg
    41341 acggtgcgtc ttccgtgtga gtcagtgtat cgcaacttgt agtcaaggca agcaaaaggc
    41401 attttctcaa accccggcct ggagcttgcc ttcgtcggcg tgatgagatt gtcgtgaagg
    41461 tggcgaacga ggatcgggag tggattttag gacgcagctt ggagcagtgc cgtgagtgtc
    41521 ggaatgacct gatccggagc aatttttttc gtttcgccgg tgtgacgaag tttgagctcg
    41581 acctgcccct gcgccaagcc tttttctccg atcaccaggt gaaagggggc gccgatcagg
    41641 tcggcatcgt tgaatttaac accggctcgc tcgtcgcgat catcccacag gacttcaatg
    41701 ccggcttgtt ccatcgctcg gtagagcgac tcggcgagtt ggagaaccgg ctcagactgg
    41761 ctgagcggca acagcgtgac atgaaagggc gcgataggaa tcggccactt gatgcccttg
    41821 gcgtcgtgat tctgttcgac tgatgcggcc gaaacacggc tcacgccaat gccataacaa
    41881 cccatgacgg ccagttgttc ctggccctgc gcatccagga aggtggcctt catcgcctgg
    41941 ctgtatttcg tgcccagcat gaagacgtgg ccgacttcga tacccttcgc cgtcttgagc
    42001 acgccatcct tgcgcgggga gagatcgccg gcttgcgcat tgcggaggtc cgagaattgg
    42061 gcgactgtga aatcgcgttc ccagttcacg tcggtgaaat gggtatcgac ctggttgccg
    42121 ccgacgacaa agttcgccat ggcctttacg gaccaatcgg cgaggattcg gatctgtttc
    42181 aagccgactg gccctgcaaa gccgactggt gcaccggtca gcttgggtat caactccggc
    42241 gcgacgagct cgatatcagt tgccccgagc aggcgcttga gcttgatttc gttcacctca
    42301 tgatcgcctc gaaccaggac ggcgacggtt tccttgccgg tggtgtagag cagcgttttg
    42361 acgagttgcg agggagcaat ggttaagaac ttggtgacct cttctaccgt ccgtcgcccc
    42421 ggggtggaga cggcggtgag gggtcgtaag gccggcagcg gggatacgtc gggtggaagg
    42481 acctcggccc gttcgacgtt ggcggcgtag gtgcctccct cggcgtagac gatagtttcc
    42541 tcaccggttt ctgccagcac cataaactcg tgggaggaac ttcctccgat caatccggtg
    42601 tctgcttcca cgggacggaa ggtcaatccg cagcgagcga agatgcggtt ataggcgtca
    42661 tacattttct gatagttcag cctggctccc gcttcgtccc gatcaaagct gtacgcatcc
    42721 ttcatgatga actcgcggcc gcgcatcaag ccgaaacgcg gacggatttc gtcacggaac
    42781 ttcgtctgga tctgatagaa gttcagtggc atctgccgat aggaacggac ttcgcggcgg
    42841 aagagatcag taatgacttc ctcgtgggtc gggcccaggc agaaatcgcg ctcatgccgg
    42901 tctttgaacc ggaggagctc tttgccatag aagtcccacc ggccggtttc acgccacagt
    42961 tcggccggcg atgcgaccgg catgaggact tcctgtgcgc cggcccggtt catttcctcg
    43021 cggacgatgc gttcgatttt ccgtagaacg cgcaacccaa gcggaagata ggtatagatg
    43081 ccggcggcaa ctttccggat gaggccggcg cgcagcatga ggcgatgact gaccgtttca
    43141 gcctcgcccg gatcctcacg taatgttgga atgagagttt cggagacgcg catgtggggc
    43201 tatggggaaa tcaatcgctc gatgtcattc caaaaggcga aaatcataat accgaccaga
    43261 agtaccaacc ccacctgttg tgccagttct cgctgccgat cttcaagtgg ttttcgtcga
    43321 atcgcttcaa taaaaaagaa taacagatgg ccgccgtcga gaattgggat gggtagaaga
    43381 ttgaggacac ccaggttgat gctcagcatc gccatgagga agaccagact ggaggtgccc
    43441 tgttcggccg catcgccggc ggttttggcg atggtgagcg ggccgccgat attcttgcgg
    43501 gaaatatctc cggtgatgat cttgtaaatt ccgaccaccg tgagttcggt ccatccccac
    43561 gtcgcctggg cgcccaataa cggggctttc aagggttcgt tggtttgtaa aatagtctgg
    43621 ttctgggcag agatgccgat ttttccgatc tcggccggct ttccgtctac cgtggccttt
    43681 tcacccatcg gcgttacgga aaccgattgg gcgcttccgt ttcgttggat ctcaaactgc
    43741 aaggcgtgat tcggattttc ccgcaccagc gcggtcatct gcgaccaggt gaagatgtca
    43801 tgcccatcaa tgcgaaggac acggtcgccg gctacaagcc cagcggcttg tgcgcgcgat
    43861 cccgggatga cggccgtaat aaccggcgcg cgttcctcaa tcccgagctg gaacagggtc
    43921 gtggctttgc cgttgtcttg gacggtggtc ttattggggg tgacgagcac cgttttgatc
    43981 tgctgcccgc gcgtcaggtc caaggtgagt tgcttcccat tgctctgggc gatgtacttc
    44041 agcagttccg cattcgtcga aatttctttc tcattcaccc ggatgacccg gtcacctggt
    44101 ttcaatcctg cctgatcggc tggcgacccc gggagcacgg cttcaatttc aggaatgatg
    44161 tctttgaagc ttggcacggg aagggtgtag ccaagcccga tgtaggccgt atagatgaga
    44221 taggccagga tgaagttgaa aatcggtccc gccgccacaa tcagggtctt cccccagaga
    44281 gattgatgaa cgaaggcccg ctttttgtct tccggagtca gcggttcatg ctcgtcttct
    44341 ccgaacagct tgacgtagcc gccgagcggc acgatcgaca ggaggtattc ggtttcaccg
    44401 atctgtcgtc cgaagatctt gggcccgaac ccgagtgaaa acttcagaac cttcacgccg
    44461 acccagcgtg ccgctaggaa atgccccgct tcatggaagg cgacgagtac gcccaggacc
    44521 accaggaacg gaagggccca gtgagtcagc atcgacacca cgtcagggga ccaggcaaag
    44581 gttgttccca caacaacact ccttaggttc agggtattac cgcgtcaagg catgcacgag
    44641 ggactcggct ttttcccgag cccagcgatc cgcttccagc gcatcatcca aaccatcgat
    44701 gggtctcggc tggtgagcgt ccattgtact ccgaataatg tccggaatat cgagaaaacg
    44761 aataccgttc tgcaggaagg cttccaccgc cacttcattg gcggcgttca tcgtggccgg
    44821 catactgccg ccgatccgca gggcgtcgta gcccagttgc aggcacggaa agcgatcatg
    44881 atccggcttg aagaaggtca aggtgctcac ttcggtcaaa tccagagagg gaagatccaa
    44941 cggcatccgt tcaggatacc gcatggcgta agaaataggg gttcgcatat cgggcaggcc
    45001 caattgcgcg atcatcgacc gatctctgta ttctaccaga gaatggataa tgctctcccg
    45061 atgcaccaag acctcgatct gggtttccgg aatatcaaag agccaacgcg cctcaataac
    45121 ctccaatccc ttattcatta aggttgccga atcgatggtg attttcgatc ccattttcca
    45181 gttcgggtgt tgcaacgctc gttcagggct gacgtcttgc aactgctccc gggaaaagcc
    45241 ccagagcggt ccgccggatg ccgtgaggat aatgcgtttg acgtcctcac gccggtgccc
    45301 ttcaagggat tggaagatcg cgctatgttc actatcgatg gggaaaatgc gaacctgatg
    45361 tttgtgggct tctgcctgca tcaaggcgcc ggccatcacc atcggttcct tattcgccag
    45421 ggcgatttgt ttgccggcct tgattgcagc cagcgtgggc agcaatcccg cgccgcccac
    45481 gatcgctgaa atcaccaatt cagcgtccgg ggattgtgcg acctgggcca cgccttcgtt
    45541 gccggagaga atttttaccg gcaggtctgc gcaccgttgt cgcaacttcg cggcggccgg
    45601 ttcgctggcc agggcggcaa aggccggccg gaaacgccgg atttgcgctt caagtttctc
    45661 gtcattcgag ccagcggtca gaccgatgac gcgaaactct tggggaaacc gttccacgat
    45721 atcgagggtg ttcgtgccga tcgagccggt cgaacccaaa atcacgatgt tcttcatggc
    45781 atactccaga gcaggcgacc gatcacccgt tacacggtcg tgacgatcgc gacatagtag
    45841 tagaaggccg gtccagtgaa caagaggcta tccagacggt ccagcatccc gccgtggcct
    45901 ggaatcaggg cgccggaatc cttgaatccc gtgctgcgtt tcatggccga ttcagccagg
    45961 tcgccgatga ggccggcgag ggtgaggatc acgccaagca ccagacaatc gacgagtgag
    46021 atgctgggaa ggaaccaggc gcgtgccgcg accgctccca ggcaggccag aagaatgcct
    46081 cccgccaagc cctcataggt ttttttcggg ctgaccaccg gggccaatgg gtgtcgtcca
    46141 acggactttc ctgcgatgta ggcgccggta tccgctgccc aggtcaccag cacgacaaag
    46201 aaaatcagta aggccccgtc aggcatggct cgaatgagca gcaggtagcc gagcaagagt
    46261 ccgatataca ggacgcccat caccagcacc atgccatcgt tcagcgaatc gcgcagcgct
    46321 ttgcctgaga gcaggggcat acagagcgcc atcaccacgg tcgcgatcaa gaccgtacgg
    46381 tctgccacga ttgtcggcca ctggatgctg ctcaacagta accccgttgc gacgactcct
    46441 gcccaactcc accagggcca aggcgcttgg gccaaatgaa gccgatagaa ttctgcgacc
    46501 gccagcatgc cggagagggc aaccaatccg aagaaggcga tcggcccgag gtcgtgcacc
    46561 aggatataga aaatcggcag aaaaacaacc gcggccatca cccggcgaac ggtttccgag
    46621 gagctgcgtg gtcgagcctt gtccaccgtg ggtgacatct cctcgcactg gcatgctccc
    46681 ggtttcacca cgggaagact aggaggagac gctactgaac actcggccga aacggcgctc
    46741 gcgccgctgg tattcgatca acgcgaccaa ggtttcgcgc cgacggaaat ccggccagag
    46801 agtcggggtg aagtagagtt ccgtataggc cagttgccat aacagaaaat tgctgatgcg
    46861 ggtttcgccg ctcgtgcgga tcaacagatc cgggtcgggc aggtcgtgcg tatacagggc
    46921 ctgttgcatg gcgcgttcat cgatctgctc caaagacagg cgcccctcct gcacagaccg
    46981 cgcaagctcc ttcgcggcat cggccagttc cgcgcgcccg ccgtagctga gcgcgacgtt
    47041 caggattaac ttgtccagat gcgccgtttc ctgttcggtc gtgcgcaccc agcgcagtgc
    47101 cgatggcggc agcgcagtga cccggccgat ggtctggaag cgcacgccct tttcgaccag
    47161 gctggaacgc tcggtggaga gatagtgttc cagcaatccc atcaaggccg tgatttcctg
    47221 ggccggccga ttccaatttt cctgggaaaa ggcatagatg gtgagcacct tgatgccgag
    47281 gtcgagcgac agcgagatca attcccggac ggacttaatg ccttcctggt gaccggcaat
    47341 acggggtagt ccacgcaatt cggcccatcg gccattgcca tccatgatga cggccaaatg
    47401 tttcggcagc agatcagggt cgagttgcga gagcaggtcg gagtcgggtg caggctcgat
    47461 atcgcgggat cgaggatcgc tcatggaacg gcgtaggcac cttttcttgt gacgacgtga
    47521 atccttagac aggtaacgcg agtctagcgg tggggtgtgg gaaagtcaaa ctatatttcc
    47581 caatttcgct gtatttgcag gtggttcggc agtgtttaca ttgcgcctcc agaaaagagt
    47641 acgttatact cacgcaccgt atgagaggag taatccatga ccaataacga gaccggcgcg
    47701 ctggcgcgtt tcggggtcac cgatcgagat atcgagcagg cgctgggacg ggtgaaggtc
    47761 tccgctgtcg actatgccga cctgtatttc gaatattgcc agtcggaatc ggtctccatg
    47821 gaagagggga tcgtcaaacg cgcgacaaaa agtgtcgggc agggtgttgg ggtgcgggcg
    47881 acggccggtg aaaaaaccgg gtttgcctat tccgatgaac tcaccgccaa ggatttgaac
    47941 attgccgccg atacggcacg ctatatcgcc aattctgtgc aaggcacggc cccggttccc
    48001 gtcacccatc ggccacctct ggctcgtaat ctgtatcctc acgaccgcgc tacgatcgaa
    48061 gtggcgaccc gggaccgggt gacgctgttg aacgccatcg atgcggaagc caggcgctat
    48121 gatccccgga tcaagaacgt catggcggcc tataacaccg aatataaagt gatgttagtc
    48181 gcgacgtccg acggactcat ggtcggagat attcagccgt tgtccaggct acaggtgacc
    48241 tgtatcgcgg aagaaaacgg taaccggcag gtcggtacat tcggcggggg cggccggatc
    48301 gggctggaat attttcaaaa cgatcagcgg tatctgcact ttgcgcggga agcggcgcgg
    48361 gaagccattc tgaatctgag cgccgtcgat gccccggccg gtgtcatgcc ggttgtgctg
    48421 ggcggtggtt ggccgggcat tttgctccac gaagccatcg gccacgggtt ggaagcggat
    48481 ttcaatcgta agaaaacctc agcgttctcg accttgatgg ggaaaaaggt ggcgtccgag
    48541 gtctgcacca tcgtcgatga cggtacgctt ccgttccggc gcggttcgtt gaatgtcgac
    48601 gatgaaggga cgccaaccag ccgtacggtc ttgatcgaaa agggcattct acgtggttat
    48661 atcaccgaca aactgaatgc caggctcatg ggcattccgg tgaccggcaa cgggcggcgc
    48721 gaaagttatc agagtgtggt gttgccgcgg atgacgaata ccttcatgct ggccggtgaa
    48781 tccgatccgc aggacatcat caaatcggtc aagaagggcc tctacgccgt gtcatttggc
    48841 ggcgggcagg ttgatatcac caatggcaaa ttcgtgtttt ccgccagcga ggcctacctc
    48901 atcgaggacg ggaaaatcac ccgtcccgtg aagggcgcca cgttgatcgg cagcggaccg
    48961 gacattttga agcaagtttc catggtgggc catgatttga agctcgatga aggaattggc
    49021 acctgtggta aggaagggca gtcagtcccg gttggcgtcg gcctacccac catccgcatc
    49081 gacgaaatca ccgtcggtgg aacgaaagca tcatcatgac acgtatgatc ggagagcaag
    49141 actatacgac ggtcgcgcag gatttgctga cgcgagcttc gaaacagggc gcgacggcgg
    49201 cggacgtcat ggtggccgac ggggaaaccc tctcggtaca ggtccgaatg ggggccgtcg
    49261 atcgcttgac gaaagcgcgt gagaagcgat tggggttgcg ggttttcttt ggccagcggt
    49321 cagccagtgc gtccacctcc gacttttctc gcgactcgct ggaacggttt gtccaggaaa
    49381 cctgtgcctt ggctcaagcg gtggtggagg atcctgtctc cggccttccc gaaccggggc
    49441 agttcgctac cgaattgccc gagttgcaca tccacgatag cacgaagctg cagacggatg
    49501 agcagattgc cttggccctt cgcgctgaac gcgcggcgtt tgccgcggat cctcgcatta
    49561 cgaactcgga agggggcgaa tgcgactcgt cctccggccg gatcatttta gccaacagcc
    49621 atgggtttct cgggcactac gccaacagca gtttttccct gtcggtctcg ccgatcgcct
    49681 cggatgcggc cgggatgcag cgggattatt ggtatggcgt gaaccgatcg tttgccaaac
    49741 tggaaagccc ggaagccatc ggacaagagg ccaccaggcg cacggtccgc aagttgggcg
    49801 cccgcaaggc ggcgactggc cgggtgtcgg tgatctttga tcccgaagtg gcgggcagtc
    49861 tgctgagtca tctctgcagt gcgctgtctg gttacgccct gtacaagggg gcctcatttc
    49921 tcatcgggca actcggccag cagatcgctc cggactttgt gaccatttat gacgacggcc
    49981 ggatgcctgg cggtctgggc acgcgcccgt ttgacggcga gggattgccg acaagaaaac
    50041 aggccgtggt tgaacgcggc cggttgacca gttatttgct ggacacgtac tccgggaaaa
    50101 agttgggatt gccttcgacg ggaaacgcgg cgcgcagcat cggtgaaagt ccctctgccg
    50161 gcccgacgaa cttttatatg gtgccgggca cgaccagacc ggaagacatt ctggcgtcgg
    50221 tgaaacaagg attgtatgtg accgatctga tcggcttcgg catcaacatg gtcaccggag
    50281 attattcccg cggggcgagc gggttctgga tcgagaacgg cgagttagcc tatccggtcg
    50341 aagaaattac catcgcgagc aatttgaagc agatgtattc agccattgag acaatcggct
    50401 cggatctggt gttccgcgga cgcatcgcca gcccgacggt gaagattgcc gaaatgatgg
    50461 tcgcagggaa ctagcgacaa aggggggatg ggtgatgcaa cgattgatgg cctcaatgct
    50521 cggcgcccta ctgacgatcc ctgcgatcgg catggcggca gagtttcacg tgaccagccc
    50581 gacgatcaag gatcagagca cgatcggtag tgaacacgtg ttcaacggat ttggctgtac
    50641 ggggcagaat gtctcgcctg cgctgcaatg ggagcatgcc ccgaaggaca cgaagagttt
    50701 tgctgtgacg gtgtacgatc ccgatgctcc caccggaagc ggctggtggc attggctcat
    50761 cttcaacctt ccgccgggta ccaccggttt gtcggctggt gcaggaaatc cggacagcgc
    50821 cggcgctccg gcgggcagca ttcaaagcat gaccgatttt ggacagccgg gcttcggggg
    50881 gccatgccct cccccgggag acaagccgca tcggtatatc tttacggtct ttgcgttgaa
    50941 ggtggaccaa ttgccgctga agaaagacgc gtccggcgcg atggtcgggt attacctcaa
    51001 tcagaatgcc ctcggaaaag catcggtcac cgggttatat ggacgataag caggcaatca
    51061 tcagaacaga gtaaggaaca caccatggct cttgatgccg aacagggaaa aatcatgctg
    51121 cagctgatca cctcgcgata cgaggatcgg cattggcgca agaagatcga gaagacgctc
    51181 agtttgccgc agagcggagt cggggacgag cgccagcagc agatgtttct ctatctgaag
    51241 ctgaatttga aggcgtacaa atctaggcgg gcggaccccg acgactggat cttaggcgga
    51301 tacgccacga aggaagtcat cgatcgggcg aagtttcaac cgcacttggt ggggcaggga
    51361 atcacggctg aggacgtcgc gttcctcggt gttgatccgg gcccggatgt tgatgaagcc
    51421 tggtgggaag acatgctggt tgcctggttt ggtgctcccg aagatgaaga agcgactgag
    51481 gcaacggagg aggaatctcc gtccgaaacc gctgccgaga gtcatcctgc ccgtacgtga
    51541 acgaacgcgc tgtctggctg cttcgcctgt tggtgaggcg gccaggccag gcggcgttgc
    51601 taagatccga ataaatccat ttgctgggcg ggcgaagacg gacgctcgat ctcaagtgtc
    51661 cgtgcagcac tggcaacttc ttgttccttc gccggggctg gctgattgtg ccggtccaaa
    51721 aactccttga gcttctgaaa atcttcccgc aagggctgca gcatgctgct ttgatgcagg
    51781 gctgcggcag gatgaagcaa aggaaagagc acaaagtctt tcatgtaaaa agcctgcccg
    51841 cggactcgcg taatgcctac cttacgttcc agcagcgttt gtgtcgccca gttgccgagc
    51901 gagcagacca acttcggtcg aatcagagcg atctgtttca ggaggaacgg tttgcaggtg
    51961 tcgacttccg gcggttccgg gtcgcgatta ttgggcggcc gacatttgat gacgttggca
    52021 atgtagatat ctgcgcggga tagtccgacc gactgcagca gttcattcag caattgcccc
    52081 gccgcgccta cgaacggctc acctttttga tcctcgtgaa agcccggtgc ttcccccaca
    52141 aacatgacgg aggcctgcgg attgcccacg ccgaatacca cctgacgccg gcctagtttg
    52201 gcgagcgggc atcgttggca gtcgtgaagc gagtcggcga gttcctgcag ggcgatatgc
    52261 ggtgaagaca tggacgtgac atctcgcgtg gagcgccaaa tcttagtcgc gccatcgggg
    52321 cttgtcaacg ctgcgctgcg cgttggcgcg caccggtgcg agtcgttatg agggacgggt
    52381 agagatggcc tcggcacaac ggtggccgct gagaatggct gattccagat tggccggcca
    52441 tcccgtgtcc gtccacgctc ccgccacgaa aaaattggta aaggggctgg tcgagatcgg
    52501 tcgatactga tgcgtgcccg gtttgctggc cagcatggcg gaggcgaggc gcatgacgtc
    52561 gaagtcgaga atgcgcggcg gcgacgtcgt cggaaatgcg gccgccatgg catccgcggc
    52621 aaggcgaacg agttcttccg tcgactgtgg caacagactc ggctcgccca ccgcctgagc
    52681 ccagaggacc gacgtctgct cgtgtcgctc ttcatcggga tgacggatga tccagtggaa
    52741 agtttttcct tcgaggagga tgagctgtgt ctgtcgaacc ggctggtcga ggtgcaggcg
    52801 aaccatcacg agcggggatt cgctgagacg gctgagttgc tggaaatagg catagtgagt
    52861 caccacgcgt tccgggagaa gcggtgtgag acgctggggc ggcagcgcgg agagatacca
    52921 gtcggcagtg agcctggtcc gatcggctaa ctcaacttct gtgactcggt tgtgtgagaa
    52981 gcgcacttga gtggctgtgg cattcagttt cactcgaacg ccgagccggt cgagttctct
    53041 cgtcaggggc gccagcaaaa atgaatccac tccttgaggc ggcacgatca gcttcgttgc
    53101 ccgggcaccg gtcaagaaac accgccgcaa ggtacgcata aacaggccgg cagaaatgtc
    53161 ttccagcgcg gctcccaaca acagcctggc gagactgttc cacacaccgt gacgggcggt
    53221 ttccgactgg ccgatgctcg tgagccattc gtcggccaca cgcgagtcga gatcgttcgg
    53281 cagcggcggg tcctgttccc aggtccgctc gagaaacgag agcaggtgcc agcggtcacg
    53341 catggacagg ccctggaata aggtcgtccc gagcaacgta tttaatggag aggggagagg
    53401 aagatgcagg aactggatgc gggcgccggt cgattgcaaa aattccaacg gagtatgccg
    53461 gagcggtcgg gtcactgcgt cctggccgag agtcttgagc aatgaccagg tggctccatg
    53521 cgcttcgagg agaatgggtg gcggcgcatg ccacatccgg cctccaaggt gagcgccttg
    53581 ctcgatcacg gtgacggcgt ggcctttggc ggcgagggaa cgggccgcgg tcagaccggc
    53641 gatgccgccg cccaggatga gcaccgatcg gctcatgggg cggaggagag aaggcgggag
    53701 cgcagccaga ctccggctgc caccgctaac cggtggctag gggtgagggt cacccgatct
    53761 ccgagcacgc ggtaaccgga ttgctcgatg cgctgcaaaa tacggctgta cacaccgcgc
    53821 atgatttcgg ctacggtcag agcctggcgt tcttcgcgtg gcagtgactc gagcgcgcgc
    53881 gcggctttgg cataaaattc cttcgcgcgt ccgacctcat agatcatgag ttcggtgaac
    53941 tccggcttat accggcggtg cagaagatcg tcttcccggt agccgaagcg cgtgaaatcc
    54001 tcctgcggca gatacacgcg tccgcactcg gcgtcgttgc ccaggtcgcg cagaatgttg
    54061 gtcagttgaa aggccatgcc gagattcacc gcataatcct gggcgcgcgg agacgtagtg
    54121 ccaaacacgt gcaggcagat caaacccacg accgaggcta cgcgataaca atagagcgag
    54181 agttgctcga acgtggcata tcgggtggtc gtgaggtcca tctcgacgcc cttgatcaat
    54241 tcttcgaaat acgcctgcgg aatggacaat tcgcgcacgt gtcgggcgag gctgatggtc
    54301 accggcaacg tcggcgtccc ctcataggct gcgctcagtt cgcggcgcca gcgagccaac
    54361 tcctcttgcg gatggctacc ggggggtggt tcgtcgacgg cattgtccac ctccttgcag
    54421 aaggcataga cggtatacat ggcgtcgcga cgcgcctttg gcaggaagag aaaggaatag
    54481 taaaaattgc tgccactttt tttagtcagg gtcgtgcaat aggtttgcgc ttcggtcggt
    54541 gtcatcatcg tgtcattgac gtcggaatgt catcggaggt gagttgctcg acggcctcgg
    54601 gcagaccatg attgaaacaa gccgggtgga agatggccgc cagctgttcc acgccatcga
    54661 tgagtctcgg gcctggtcga ctgaagtacg agagcgcatc gaccagatac acctgtcccc
    54721 gtcggacagc cggaaggtcc ttccattcag ggcggctcgt gagggaagcc agttccattt
    54781 tggtgcgggc aacagtaaac ccgcacggca tcagcacgat cacgtccggt tcggaggcag
    54841 cgaagacgtc ccagtcaatt ttgtgagagg cggcaccggc ctctgccaga gcatcgatac
    54901 cgcctgccgc tgccaccatg tcgggtaccc aatgaccggc cgtgtataaa ggggacagcc
    54961 attccaggca ggccaccctc gggcgcagcg attctttctc tatccgcgcg tgcaccgcgt
    55021 cgagcctgcc acgaagttgg ctcagaaacc gggttgcggt ttcagcctgg cccaacgcgt
    55081 tgccaagcgt ggcaatgtcc aacaggatat cgtcgagccg tcgcgggtta agagtcacca
    55141 ggcgcggagg cggcgccagc ttgcgcaaga tccccgttag ctgtgtcgga gtgatcgcac
    55201 agacatcgca caaattctgc gtgatgagca cctcgggctt ggctgccaga agccctcgtt
    55261 cgtccagttc gtagaggcct tcaccggccg agagcatggt gctgacttgc gcatcaatct
    55321 gcgcactgga tagtgaccgg ctttcgatgc gagcgcggac catgacgggg acgtggctca
    55381 gctgcggagg gaaatcacat tcatggctga tgccgaccag ttgatcggcg agacccagcg
    55441 ccgcaacgac ttccgtggct ccgggtacca gcgaacaaat tctcataaac ggccttgagc
    55501 cggtccccag aggcgcgatc ggaggtccga gagtctggtg tccgccaatg aatgcgtgat
    55561 ggcgtctgcc tcgccgagat cctgcactgt gtgggtgttg gcgactgcaa ggactttcat
    55621 gccggccgct cgcgcggccc tgatcccggg cagggaatct tcaatgacca ggcagtcgtc
    55681 tggagttaat gccggttgcg acggctgccg attcagggcg gccatggcat ggaggaatgg
    55741 ctctggcgca ggtttccccc gagtcacgtc ctcagcgctg gtgatatgga gaaaggcttt
    55801 tcggagcccg gcttcctcga gaatcaattc gatttcgttc cgcagcgctc ccgaagcaat
    55861 ggcgagtgga taccgggcgg cagcgtcatg aaccaactcg cgcacgccag ggaaaatcgc
    55921 cagatgttct ctgaccgcgg acagatacgc ctgagcctta cggtccatca attcacccag
    55981 gagtgtgggc aacgcctgcc gctgatgcga ctgtaatgcg gccaggaaac acccgcgatc
    56041 gtcaaagccg agataatcgg tgtagtactc ttgttctgtc agggaaatat cgatgccggc
    56101 cagaacctgt cgaagggccg cgaaatgcag cggctcggtg tcggcaatta ctccgtcgaa
    56161 atcaaaaatg agggcgcgta attcgctcat gaggtccggg cctatcctta tgcggagatc
    56221 gtctgagacc ggtttgccga ttatgcgggc gcagcattat agcaagggtg gcgtggcaaa
    56281 aaaagacgac ggcccgttcc aagggaaacg ggccgtcgtt cgcgaagcga aaagcaggaa
    56341 tgtacttagc gtttcagcct gagactgcgt tcagaaatcc aacctttttt gccgtcctgg
    56401 gtgcgcactg agtagatcca gccgtttttc tggtattccc cgtcaagaat cgtcagcgtg
    56461 gtgctggccg gcacggtggt gctggttttc gtgccgatgg aatcggcaaa taaaggcatc
    56521 ggagacttgg gcctgctggg atcagcgatc accatcaccc gctgaccttc cgcatacaac
    56581 ggacccgcca ctctgacggg cgccgaagcc ggtttcatcg caggaacggg agcagggacc
    56641 acagcagcgg gtgctggtgc cggcattgga gtcggggctt ccgcgggcgg cggtggcacg
    56701 ctatcgacca cggcgggcgg agccatcgat ggcgcaggtg ccggcgcagg tatcggtgcc
    56761 gcaggtgcct gtacggcggg cggagccggt ttcggggccg gcgccggcgg tcgctgggcc
    56821 acgggttggc tggtctccgt gccaccatcc agatacggct ggatcatctg catggctgcg
    56881 tcaggatcca tggccacata gccgatgcct cctaccagaa ggagcagcag tatccagagg
    56941 aagggaccct tcttggatcg cttgggcgca ttcatcggcg gggccggtgg cggcacggct
    57001 tcatccaaat cgtcttcagt gaattccaaa tcaggctcgg gctggcttgc gaacagcaga
    57061 cgccagtctg tccacacact gcctatcgca ggaatgcccg tagatgacac catcggagga
    57121 cctcctcatt cggaatcatg gcgagagtct gtctaatcgt aggtacttat cacccgttct
    57181 ccgacctgtc aattttgttc gagaaaacga cgacatgact ttccgggcac ggtgcgcctc
    57241 gcgagcggag ctcacgacgc ctgatgagtc agccgcgcag gcgaatacac gatcattccg
    57301 atggggcatt cgccgggtca tcgcgcacat gcacaagggc ttgcaagttc gaacttcccc
    57361 gttgcagaat cgcgcaccac ctgtgcacgg agaccgatga gatcctaccg agaagagctc
    57421 tggttcgaga cgaaaaccag gcgcgcgtat ctgaacatca cggcccaggt tgaagccgcc
    57481 gtgcgaaaga gcggcgtgcg tgaaggactg gtgttggtga atgccatgca tatcacggcg
    57541 agcgtctata tcaacgacga cgaagccgga ctgctccagg attatgacac gtttctggaa
    57601 cggcttgcgc cgcacgacgc gacctatcgt cacaataaca cgggcgagga caatggtgat
    57661 gcgcacatca aacggcagtt gatggggcgg gaggtcgtgg tcgcgatcac ggatggtaag
    57721 ctggacttcg gtccctggga acaaattttt tatggtgagt ttgacgggcg acggcgcaag
    57781 cgcgtactgg taaaagtcat cggagaatga cgacgcgatc cttgtacgga gacgctgcgt
    57841 cggccggagc gataaggaac cgcattcgcg cttgccacgt atgggaaagt ttggcaacat
    57901 ggacaacagg atgaacgacg actacctcgc aacacgaacg cgcatcgacc tgggaggcca
    57961 gccatgttga gttggtcacg accggacccg ctgacgcgag atctgatcca tctcattaac
    58021 gcccgacgcc acgatcacgg tgataccgac gcggcgatcg ataccctgca agccttcatt
    58081 gagcaggggc gggagcagga tctgttgacc gtgctggccg cactcgacga ggagatggcg
    58141 gaatggatgt tcgacctggt cgcggaggcc tcctgtgccg tgatcatgga cggacctgat
    58201 gaagagaaaa acgcctatgc gttgatggcg gcactggagt tgccccttca ggccaatctg
    58261 ggccagcccc tcggattaaa gatcgacccc gtggcgacgg ccgatctcct tcaccggcat
    58321 cttcacattc ccgcaggcgt ggtcgtgcgt gtcgagccgc ggttgctgac cgatgcgaca
    58381 ctcgaagggc tgacgctcca aacactcaac gagcacctcg caagtatcgc cgattcccaa
    58441 cgcacgcagg ccattgcctc ccggctctat cctccggttg aaaatacggc cttcctcttt
    58501 ttccagctga tcgggatgcc ggatcccgga ttgcccgact cattggaaga gccggaacgt
    58561 cgcgccttgc tcgagggcct ggtgacccaa tgttccgaac tggcgctggc cccggacacg
    58621 ctggaggtgc cggtgtatgc gtcgtatgcc ctgttcgatg cccagaatgc cgtgcggctg
    58681 catcgcctgg ccgacgaaac cgccgctgtc tggcgtgacc tcgatccgat ggtgcgggct
    58741 cgcacgatcg tccacctgca cacgcagtgc gggaacgggg tgtatatgcc ggtctggaca
    58801 gatctctttg atcccgagtt gccggaggac catggtccgg tgtggacttc accggatgtg
    58861 tgggtgttca cggccgacct gccgatcgag tggccgggcg aaatgctgac gaatcgtctg
    58921 ctcgccgagg gctgcactcg cttcgagaac cacatcgtcg aagcgcccga aaactgacgg
    58981 tcgctgttcc gtttgccgat cgagttggat actctcatag aggagtttct tggctggctc
    59041 atcgcgaatc ggcgctgtcg tgctggtgac cctcctcagt tgtctggtgt taggcggtat
    59101 ctggggagtc gtcctgtttg tccttccgca aagcgagtct cctcccgagg ccctgccggt
    59161 gtccgttccc acgcctccgc ttccggttcc tgccgcgacg cagcccccag accgccctat
    59221 gatcgatgat gctgctcgcc ccggcgtggc gaatgctgag cctccagtcg tcgtgccgca
    59281 accttccgtt ccgcctgttg ccgaggccgc gcgcatgccc atcggacggg aggtcaaatg
    59341 cgcgctggag atggatgcgc tctgtcctga agaggaaggg gaccggcggg cctgtttgca
    59401 acggaaggca gcccagatgt ctcagccttg tcgcccgatg ctgcgcgaca agcttgctcg
    59461 aatgaaagaa aattggcagc aacttcgagt ggcgtgcgaa gcggatcgac ggcagttttg
    59521 tcgtgaggtg ccgtcagcgg gcggcgaatt gttgcttcag tgcttggaat cgcatgcgca
    59581 agaagtgtcc gatcagtgct ttcaattcct tccgaagcgc ggtcgtctgc tcaattagtc
    59641 aggcggcgtg gctccgttcg tctcgcaaca caaagcgcat cgtaattccc gcgacttcca
    59701 ccacgtctcc atgccgcagg gcatgttctc gctgaaccgg ccggccgttg accagaatgc
    59761 gtttcccgct ttccgtctgg ctgaccacat aggcctctcc gcggcggctg atcatcgcgg
    59821 cggttttcgg tgcaaaccag ccggtgagag tgatgacggc atcatcctgc gcgccgatca
    59881 gtgagacctg tctcgtcaaa ggatagtgcg attgaccggt ccggccagaa agaatttcca
    59941 cgattcccac cttgcgtgcg ggagccggtg actcgcgtgg cgcctgagat ggcaccacca
    60001 tggtcttgtc ggccacgagc atgtctgcgg ggatgatggg ttctgctgcc agtcctggct
    60061 tctcgcgaaa aatcacccga tgagttccaa accggagcgc atcggcatcc tgcaattgac
    60121 gccgatcgat ggggtgttcg ttcacgaaac ttccgttggt gctgctgagg tcctcgagaa
    60181 acagcacacc ttgaacttgg acgatgcggg catggtgcgc agaaaccgcc ggatcttcca
    60241 ggcagagatc gttatccggc ttgcgaccga tggtgaaggg ggtgcgccta atttcacatt
    60301 ctctcgtgcc gccatgaggg gatctcacga gcaggagggg tggtatcgag tgctgagaca
    60361 tggaggctcc ttcaaagtct atctaggctg ggggcgaaac caattgggtg taaatgcggt
    60421 cccagaggct ggtgggccgt tgcgtcacca gcgccacgat gacggtcgcg ttgtcggtgc
    60481 cgccggcggc attcgagaga gcgatgagac ggtctgccat agcctgagga tcgatggatt
    60541 cctgactcac tcgcaggatg acatcggccg tcactccagc ggtcaatcca tcggagcaga
    60601 gtaacaggat atcgtcgggc agtaccggca tctcccctaa ctcgacgtcc accaggggat
    60661 gcacacccac cgcacgggtc agcacatgtc gatgcggggc gcgcgccatg tctgcagcgg
    60721 ccaagagtcc ggattgcatt tgctcttgaa cgagcgaatg gtcgaccgtc agcaactgca
    60781 ctgcgccgtc acgaatcaga tacagtcggc tatcgccgac gtgagcgatc gacagaacgg
    60841 ctccagtaag ccggactgcg acgaccgtcg tccccatccc ggcatattcg gtgcgtcgtg
    60901 ccgcttcctg atgcacccgg tgattggcga ggcgcaccgc gctcgccaat cgattggtgg
    60961 ccgaagaaaa ctctggacgg gaaatgccta tcaacgggag ggaccggtct gtctccgcct
    61021 ccgcaagatg gtgagcaata gtctcaaccg tgcggctgct ggcgatttcc ccggcccgat
    61081 gcccgcccat cccgtcgcat acgacaaaaa ttccggcggc cggatcggca tgatagcggt
    61141 cttcgttgag gcggcggacc aggccgacgt ccgaagcggc tccatgtgtg acgtgccagg
    61201 cgtgcatggg cgtggttatc tcggcatcac ctggaagacg tcacggaggt cttgcgccat
    61261 gtcccccgca tgccggtagc ggttctgaat ctctttctgc agcgcccggt ccaggatgct
    61321 ttggacgcgc gtcggcaggt cgcggcggta cttcatcaac ggggcatgtg gagacttggc
    61381 gatacgcatg accagcgccg gcatattctc ggcatcaaag ggccgttctc ccgtcaaaag
    61441 ttcgaagagc acaataccga gtgaaaagac atctgagcgt ccgtccacgt cttttcctgt
    61501 cgcctgttca ggcgacatgt accgcggcgt cccgacgatc atgctgctct gtgtttttga
    61561 agcgctcgcc atcttggcga tgccgaagtc catcaccttc accaggcgtt gcttgaggat
    61621 catgatgttc ggcggtttca cgtcacggtg aatgacgccc tgactatgcg catagtccag
    61681 cgcttcggca acggtggcca cgatctgcag cgcctgtttg gctgggacca gcgtcgattt
    61741 ctggcagtaa cagttgagga ggactccctc gagatactcc atggcgatat aggccaggcc
    61801 gtcctgctcg ccggcgtcgt agaccgtgat gatattcgga tgggacaggc gcccggtgga
    61861 ttcggcttcg cgaaagaacc ggtctcgaaa ctctttcagg tcttcttcct tgtcgatgtc
    61921 gtccagccgc atggttttaa tggccacaaa tcgctggatc gtcggatctt ttcccaggta
    61981 gacgactccc atggcaccgc gccccagttc cttgagcacc tggtatcgtc ccagcgtaga
    62041 cggcacgccg tttccgttgc gcacggctat gccggctgtc gggcgggggg gggcggcggg
    62101 aatggcttcg tctgccgcac gcacctcgtc gggcttctcc gctcgcaccg gttcttcggc
    62161 aaccgcccgg cggcgtggac gccaggcaaa catgctggtc agggcatcga catgacggac
    62221 ccaggcaaac gtcagccagg tcgctgagcc gatgaggccg ccggtgacca accaggtata
    62281 gagcggctgt ctaggcgggc cgagcacaga tatgccgtgt gcttcatagg cctggaatgc
    62341 ggcaatgacg atcagaaggg aggcggacgg gaaaagaatg gcgcggagaa aggtttgacc
    62401 cttgccgttg tccttcaggt ctcgtctggc tcgcgaggcc gcagaccaga tcatgagcag
    62461 gcagatgccg tctgcaatga accgaacgac ttgcgcgacg ttcatgccca acggccggag
    62521 gtaggtgtgc gtaaacagcg ggagggtcgc gagaaatggc ccgaccagaa ccgcaaggag
    62581 aatgacgatg aaatacgggc cgatccagcc ccaagatgtg gtcatgtgtt ggcgcggtac
    62641 gtcgttgtag ccagtgtaac ggaaggtcgt actgtgtcaa cgaaacgagg gaatcacgca
    62701 ccgccggggc agagtctcgt ggcatccgga tgaggacaga ggaggcgtgt ttgggagaaa
    62761 agggctcagg acgaggtggc ggcttttctg agtggatcga gcaatttctg tgagactttg
    62821 agctggccgc ggccgatccc gacctcaata tccggtttgg tgacgccgtg gaaatcgctg
    62881 ccgccggtga cgaggagatc gcattgcctg gccagatcca ggtattcggt cgtttgactg
    62941 ggcgtatggg tgctgtaatg aacctccatt cctcccaatc cggcagcctt gaggtctctc
    63001 acaagtaccc gcaacccttc ggcggatgtt ctgacccacg tcgggtgggc gagcaccggc
    63061 acgccgccgg cttcgcgaat ccatcgcacg gcttcggccg gttccggtaa ttcccggtcg
    63121 acaaaggccg ggcggccgtt tgccaggtat cgatcgaagg cctctttcgc cgaggtcaca
    63181 aattttttct ccatcaaaag acgggcgatg tgggggcgcc ccacggattc cgtgcctgcc
    63241 agggcccgca cttcttcata agtaatcgga atgcccaatt cgttgaggcg ttgaacaatc
    63301 ttaggattac gaagatgtcg gctgtcgcgc aatgtgctca ggcgttgcgc taataacgga
    63361 tcggtccaat tcaaaaaata tccgaggata tgcagttcgc tctctccgag ccgcgaactg
    63421 atttcgacgc cgggaactac ctcgatgccg agttcttttc cgatagctgt cgcttcggga
    63481 atgccgtcga caatgtcgtg atccgtgatc gccagcgccg tgaggccggc ctgcttggca
    63541 aaggccatga cctcggccgt ggagcaactg ccgtcggagt gcgtggtgtg cagatggaga
    63601 tcaatgcggc tcatggtgat gtctctggcc ccgttttctg cgcgaccagt cgcgcggtgt
    63661 agcatggccc gctgccatga cctccgtcgt gttcgccctc gtcatagtga agaacgcgca
    63721 ggggcgaggt gaggcggagg agttcgttct gcgccaggca aaactcccat cgccgcggat
    63781 gctgatggcg aaaataattg tcgatggtaa atgtttcgta gaggaggatg ccattgggtt
    63841 tcagggcgtc aatgatgaca gggaacagag gccgatgcag gtaaaaaaag acgacgatgg
    63901 catcataaca ttcgtggccc aagctgggcg ggtgatccgc agaggcttcc aggttgagga
    63961 cgcgtgtcgt gagaccggag agacgctgtg tgcccgcagc ggcttccaat gcggagaggg
    64021 cgtcggtgtc tcgatcgatg gcctccacct gtgacccctg ggccaggagg tacagggcat
    64081 tccgtccgcg tccagcggcg acgtcgagga tgtgtccctt ggggagacgc gcaagttgtt
    64141 ggatgagaaa cggtgcggcg ctcagtgcct ggtgtgttga ctgatgggcg gcacgcgtgc
    64201 gttcaaaccg gatgccgact gacccggcga ccatggccag cggggcatgg acttttcgaa
    64261 tccagatgcg gacccgatca gccggaaatt ccgcgaataa catgccgacc aactgctcgg
    64321 ccagggtttc aagaagctgg caggtgaggc tcgtgctgag tgcgacgatt cgttccgcta
    64381 cttgagcata atcgatcgtt tcactcaagc gatccgaaac cgcggcggct tccacggcgg
    64441 cgtccagttc gaggtcgacg acgatcagct ggggtttgcg gcgttcttcc tccgtcacgc
    64501 cgcagcggcc gtagaactcc aggcgttcga tgacaatccg ctctgccatg gcggcattgt
    64561 cgtagatggg ctttcagact gtcaagcaaa gcgggcgcgc cattgagcta ggagcgtgcg
    64621 aagagacgct tcgtgagcca attggcgggc gaggcgaacc ggcgggcaga ggcgacgatc
    64681 gtcgcaggag aacacttcgc cgtgaagtct tgcaccatcc gtctcgcacc cctgtacaga
    64741 aactcggtca cgtcactgac tgtcggttgt ggggtacggt tcagatgaag ctgcttcaat
    64801 tcggccttgt aggctttgcg gcggcggcgt gtggcatgaa tcgccacggc cgcgacaacg
    64861 gtcaacagca agggattcga ggggatggag aacaaccacc gccaccattc atagaatgcc
    64921 agcacggtca ggcagagggg cagcgtcaac acatcaaccc atgccgattg tacggcgcgg
    64981 atctgttcgt ctatcgattg accgttgaac cggcggggta tgctttgcag ggacgtgcgt
    65041 cggtttttcg aggtgaagac tcgcgcgggg agaaacattc cgggtacctc cagtagtgaa
    65101 cgacatcctt ctggaggcat tgtaggacag gttgcacaat cagaatagaa aagacggaat
    65161 ttctgcgggt gtcgactcgg tagttttacc cgtatgnnnn nnnnnnnnnn nnnnnnnnnn
    65221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    65281 nnnnnnnnnn nnnnnnacga atcgacgtgc ccgccgtggc tttcaattca gtggagccga
    65341 tgcagcacgc cttcggcgac aacggagctc ggatcgccac cgacaatcaa atccttatca
    65401 ccgaaatggg aggcggtccg cgtcgtcacg cgcatcttca ttccctcggg gaccagcgtg
    65461 tactcaaaca aggcggcttc ctggcgttgg tccatatacc cctgactggc gcgttcgaac
    65521 gagccgataa tactgatcga cacacgcccc gggccctgtt cgaaacgctt cacagccatc
    65581 cgttgcacac cgccacctgg tggcacgtat tcaatcgttt gcccgacgtg tgacaattcc
    65641 acctggcgtg tgacgccctt gttgttggta taggagtaga gagggaggcc ctgcggactg
    65701 aagtcgattt ggacttcagc ccggctgccg tctgggctgc tcaggacccc tttccacgcg
    65761 ccggccaatt ccgcggcctc agtggagccg gatacggcca ggacgccgat gatcgctgcg
    65821 atgtgcacga agtgtctcat agtcatgagc ctaccctcct gtgcgatggc cggtcgcgcg
    65881 ccgagctctc ttatactttg aatggctgtt gccggagaaa gcgccccgcc gccccgagcg
    65941 taaacagatt gggcgactgg ctggcgggca gccccgcctt cactgccgca tggaatttgg
    66001 catagttccc ccgatagttc ccgtggttcc acgccttcag cacctgttcg gtaaaggcgc
    66061 cattgtggtc gccgtccatg gacgtctggt tgtcctggca gcctgaaatg agaatcacgg
    66121 caggatgaaa ttctttggcg atggccgtga ggcgggggct cacggccagt tgggccagca
    66181 cgctgtccgg atccgtcgtc ccggccttgc cggcggcttt cgccacgtca tgctgcaatt
    66241 tgttgtagaa cgcctgatgt tcccgatacg tccgaatggc gacggcaggg ggcatcattt
    66301 tcgagcgtcc cgtcactttc gtccgatcaa tcggcggtgg gacggcgcgg gtgaccgtac
    66361 cgctatggca gctgtccgac aacacaagga ttcgcacgcc cgccgcaaag cggctgagtt
    66421 cgaagtacaa ttcatcgtcg atgagttgac cgtcgtacag acaccaggtc tcatcctgct
    66481 tgtcgatttc ttctcctgtc acgtcgggca cctgaccgcc atggccggaa taggtcagaa
    66541 aaaacagatc gccttgtttg agctgcttcg cggcttttcg catcgcagcc agcattttgg
    66601 cgcgggtgcc ttgtttggtc agcagcacgg tggatttcat gccctgcgat ttggcgatgg
    66661 ccgccatgtc tttggcatcg aactcacagg cggccagttc accgctccag ccgccatagg
    66721 cggcgggact cacggcgttg aggccgatgt gtaacgagag ggctttcggc tttgcagcgg
    66781 atgctgtggt ggttttggcc atacgtacct ccttggtcgg ctggctccat gtcttgatag
    66841 gttcggatga agagcaaatg atggcggtac ggtaatcgtt acgccgaaat ctgtcaacgg
    66901 agcttcgtgg gaaatactgg tattgtggcc gtccggtgac gctcatggat cgggacgaga
    66961 tgtggcgatg aaccacatga ttaggtgtcc tcctcctcga tttcttcgat tgactccttg
    67021 atcgcagcca caaatgtttc cggtgcggcg agggcctgcg cagtcagttg gaattcagag
    67081 accagcaccc catctttatc cacgacgatc agccgatacc cttgtttcac gaccacgacc
    67141 tttctctgcg catttcgcag gcagatgcta ttgacgagag gccctacggg caggctactg
    67201 tatcgaacga tcagccgtca tgtcttcgtt gggaggcagg atgaccggtt ggtgttcgcc
    67261 attcaggcct ggtaggatga cacaatcacc agtacgattc gatcgtccaa ggaaaggata
    67321 gtcacttgca tacaaccaaa ctcatagccg catttctcgt gcttgtgttg gtcggcgtgc
    67381 cgacgatttc ttttgcgaag gcgcgagggg gatcaggggg aggattctcc agcgggtcac
    67441 gaagcggatc ttcaggaagc atgggcagtc gtggatcgcg cacctatcag gacaatgggg
    67501 ccaagcccat cgaacaatcc acgacagcca ggccttccgc caccccgccg ccttcgatgg
    67561 cgggcaatcc ttcgactgca tctaggcccg ctcccgctgc gcaaccgtca tggtttcaac
    67621 gcaaccccct tctggccggc attgtcggag gtcttgccgg aacgtggctc gggcacatga
    67681 tttttggtgc gaccgacacg agtgcccgca cgacggaagg tggtgagggc gaacaggccg
    67741 ccgcaggggc aggctcaagc ggcatgttgc tgctgttgat ggtgatgggt ggcggtgcac
    67801 tctggtggta tatgcggtcg cgacgtacac cggcgccgaa tttttctggg ctttcgcgaa
    67861 ccagtgtcgc gagcggctca ttgctggccg aatcatcgcg tgcaggattc ggggcggccg
    67921 ctgttgagga ggagatgacg tcaacagaca aggcggcgtt tcaacaagcg ctgatcgata
    67981 ttcaaaccgc ctggagtcac caggacctcg ccggcttgcg tcgcctcgtg acgccggaaa
    68041 tgctggatta tttcagcacc ggtctggccg agcaggccag tgagggtgtc gcgaatcgcg
    68101 tggaagatgt ggtcttagga caggcggaag tccgtgaatc gtggagtgaa ggtgcgacgc
    68161 aatatgcgac ggtcagtctc tgctggagag ccaaggacta caccatctct ctggcgaagc
    68221 agccgggcga acagggctac attgtggagg gcaacgctga gctgccgatc gaaacaacgg
    68281 aggtatggac cttcatgcgg tttggagccg ggaagtggct tttgtcagcc attcagcaag
    68341 tgtcatagcg gaatgttgaa aaatcccgcc agcttcgttc tcacgtcgtt cagaggatca
    68401 acgtacggct cgagtacgtc tcacctcttc cctcgttgcg gccttgctgg acgggatttt
    68461 tgaacatccc gcgggcctcg tgaattgcga atggatcggt attgttcctt ggggtagtca
    68521 caccggtggc tgcccccgtt gttctttggt tagcgtgtat gtgatgcctg ccgcaaacgg
    68581 gtagcggcgg tgtcttcaat aggcaggcaa ccttgggctt gagaaattgc ctcgagcagc
    68641 gcatgccgct cctggtccgt ctcctgcacc ggcggcatgc tgtgcacgaa ttgttctgcc
    68701 gcctccacca agcgttgcag cctggtggcc atttcgtccg acggtgcctg gagttcggac
    68761 gaagtcttgc gagccagtga ccgctttctt ctcggcccga catagatctg cggggccacg
    68821 ggattatcct tctccaattc cggtcgtctc gatatcggca tgcgtcctcc caaatggcaa
    68881 acgagtaatg cccactctac tcgattctgc cgcgcgtttg catggtcgaa atcattcttg
    68941 tctcaatgga gaggtgagcc tgaatccgtc aaacgattca tggcttgtca cactgattat
    69001 ctggaatcgt aaccgtgtca tggctgcgat tgacggggcg ccacagggat gacgggtgag
    69061 gtggtatgtc gactcagata gaccgttagg ggaaaacgag tgcaccggtc aactgtatgg
    69121 aaggattcag ggaaatcgca tcgcctctga tcgatgcatc agtcagtctc tcatttctcc
    69181 ttcggtgaat tataggcacg actgttgcgt cagtaattgc cgttgttgta acgcgaggtg
    69241 acattcattc ggccaaggct gtcagcgatg ccggccagag gagtgaagca tgcgccagtc
    69301 tctcggaatg cgttgctatt ttaccgcctt cgccatgttt ctttcggccc tcgtcggccg
    69361 gtcctgggcg tccaggagat aggttgcgct agcaatctcc cggtttcgtg tctgtcagcg
    69421 gtgttttccc tcacgcagtc ctttgtctga ctgaattcgg ttccttcctc cttgatcccg
    69481 ctcggaccag atactcgcct gccgttcaac gcgctcgatt tcgttgacga ggcgcgggca
    69541 tcggccggat gtcgcttgac tcccattttc cccggctcct ataatttggc ggttttgatg
    69601 cgacaaccag ctgatttggc ataaagaatg gccgacttta cgcatttcaa cgaatcgggg
    69661 cgggcgcgga tggttgatgt cggggcaaag gcctcgaccg agcgcctggc caccgcgcag
    69721 gccatcgtct tcctgcaacc ggaaaccctt gaaaaaattc agcaaggaaa gatcgcaaag
    69781 ggcgatgtgt tgtctgtcgc ccaggtggcc ggcgtcatgg gggcaaagaa gaccccggat
    69841 ctcattccga tgtgtcaccc cattttgttg acgagcgtcg atatttcgtt ccaggaaatc
    69901 gctcaacggg accgtgaggg gcgctgctcg atcgtgatca gtgctaccgc caagactacg
    69961 ggcccgacgg gcgttgaaat ggaagccatg acggccgctt cggtggccgc gttgacgata
    70021 tatgatatgt gcaaggcggt cgatcggggc atgagcttcg gcgacatctg tctgctgacg
    70081 aagtcgggcg gcaagtccgg cacctatcaa cgtccggttc cagtgtaagg gcgtgacatg
    70141 gtaacggttc gactcttcgg catgacgaaa atgttggcgg gaaaccaagg tgccttgtct
    70201 ctggccctgc cggaaggccg acgggtgaaa gacctggtgt ctgtgatcga agccgcctac
    70261 ccgaagatcg gtgagttgct ccacaagaaa aaagtgctcg tttcggtcaa tcaggatatc
    70321 gcgcatgagg atcttgaagt gcgtgacggg gatgaaattg ctttgctgcc gccgtttgcc
    70381 ggcggaagtg ccggatgctg aacaagcctg ccagcggcgt tctcgctttg cgcgtcggct
    70441 cgacgtactc aaaggtacgc ctcgcctccg tgcgcgctgc ggccttgccg gacaggcttg
    70501 ttgagcatcc tttccgcaga gccaacggga aaccggaggg agagaatcga tgagtcttga
    70561 acaggtcacg aaagccgacc agcccgttac cggcgacgag gcgatgctgg ttcgggtgca
    70621 gcgagaagat ttctcgatcg acgaagaact ctgccgtgtc cgcgctcgtt ccaagcgcat
    70681 cggcggcatt gcgatctttc tggggactgc cagagaccgg tcgaagggaa aagatgtcga
    70741 cggcattacc ttcgagcatt acgagggaat ggcgcagaaa aaattgcggg agattcgtga
    70801 acgcgcgctg aaggatttcg ggatcatcga actgtcgatc ttgcaccgat atggcgagat
    70861 cggcatcggc gataacattg tattgattat tgccggtgcg gagcatcgag ccgaggcctt
    70921 tcaggcctgt aagtgggcca ttgatgaatt gaagcaaatc accccgatct ggaaactcga
    70981 gcacactccg gaaggcgagg tgtgggtcga ggagcaccct tagcctatcc cgacagcaat
    71041 agggaaagag gcccgcgtcc tcgacatatt atggaccaca cgcccgatac acccgttcct
    71101 acgatatacg accggctggg acgtccgctc cgcagcctgc gcctgtccgt gacggaccgc
    71161 tgcaatcttc ggtgtaagta ttgtatgccg gaggatgatt acgcctggtt gccgcgcgat
    71221 accattctga ccttcgagga gatggcggag ctcactgcag tctttaccga gctcggggta
    71281 gacaaggttc gtctgacggg tggggagccg ctgttgcggc gggacctgcc ccgatttgtc
    71341 cggcagctgt cggaaaatcg acggatcacg gagattgccc tcaccagcaa cggcgttctc
    71401 atggctgatc aggccgccga tctctcgttc gccggtctga atcgcgtgac catcagcctc
    71461 gataccctcc gtgcggaccg attccgtact ttgaccaagc gggatctcca tcaccaggtg
    71521 tttgacggca tcaaggcggt ggtgcaagcg gggtttccgt cgctgaagtt cgacaccgtc
    71581 gtcatcaagg ggtacaacga cgacgaactc atcgacctga tcgaatatgg caaaacggtc
    71641 ggcggcgaag tccgattcat tgaatacatg gatgtcggcg gcgccaccga ttggtccatg
    71701 aagcaagtat tgtcgaaggc cgaaatgctc gaactggttg gccgccacta tggcggcgtc
    71761 aagccggtgg ttgagaacag cgctgcgccg gcggagcgtt ttgtgcttcc ggatggcacc
    71821 atcttcggca tcattccctc gacgaccaca cccttttgcc gtgcctgtga tcgcagccgg
    71881 ttgacagccg acgggatgtg gtatctctgt ctctatgcga aagacgggct cgatctccgt
    71941 gcaccgctcc ggcagggccg aacccgggac gaattgaaag cgttgatcat cgcggcctgg
    72001 gaaggtcggg cggatcgtgg cgccgaagag cgcaaagcgc tggaggtgtt agggttgcgt
    72061 gagcagcgcc tcattgaaat taatcggctc cgagaagatc cccacctgga aatgcatgcg
    72121 cgtgggggat gaccgccagt gtgtgctgct cccactgccg gatccgctga tgaccctctc
    72181 ctggagcagt cgatgtttga tcctcatacg ctgactatcc tgagtcttgg attcgtgctg
    72241 gggcttcgtc acgccctgga cgcggatcac cttgccgcgc tttccactgt gctggcagaa
    72301 cgtcctaccg tacaggcgtc cacggcgatc gggtttttct ggggacttgg ccacacgctg
    72361 atgctgttgt gcgtcgggac cctcttgctg gcgttgaacc tcaccattcc ggaatccatg
    72421 gcaaatctgt tcgaatttgc cgtcgggggc atgctcgtgg cgctggggct ttccttggcc
    72481 cgccgggtct atcgtgagca gtggcatgta cacacccatg agcatggggg ccggccgcac
    72541 gtccatctcc acagtcacca cttgcaggcg gatcacacac acgggcattg gtatcagggc
    72601 tcgttgcggc ctctggcgat cgggatggca catggattgg ccggttcggc agcgttgatg
    72661 ttggtcgtat tgtcgacggt gacggggatg gcccagggga tcggctatat tgtggtgttc
    72721 ggtgtcgggt ccattcttgg gatggtgggt gtcggggcgg tactcagtct gccggtgatc
    72781 tattctgtga cggtcggtcc tcgtgcctac tggatggtgc agggactcac ctgtcttgcc
    72841 agcatcggcc ttggggtggt gatgatggtc cgaatcgggt tagccggtgg ctggtcctag
    72901 ccgcttggtt cgtcgcagat cttccgcgct cctgcccaca ctcccttttt ccatgacacg
    72961 cctcggtaac gaatgaccta tgtaaatctg tgtgcgcctt tttcagaggt atgttattct
    73021 gccgcccagt gcggaggact cgtctacaat atcgtaaaaa catgctgaca cgccggggca
    73081 cgtccggaga gcctcggcca tgaatgtacg tgtattgggt tgccatggtt cggggcagct
    73141 tgttccgggt gagaatggtc cggttcagtg cgggacctgc ggctttctga tcaatgagga
    73201 attgctagtt gatgcgggaa ccgtcggatc ccggctctat ctggaagagc agcggcggat
    73261 ccggctggtc ctcttgaccc acctgcattt tgatcatatt cgcgagttgc cgacactggc
    73321 cgataatctg gtcggtgaga tcgaggagcc ggtcgtcatc gcggcgattc ccgaagtttt
    73381 ggacgggttg cgtcggcaca tttttaacgg cacggtctat ccggattttt tccggttgcc
    73441 cgatcctgtg aagccggtgt ttgtgtcccg tgaacttctc ccggggcagg agacgttgtt
    73501 gtgcggtctg ggagtgacgc cgattccggt gaaccatgtg gtcccgacgg tgggatttct
    73561 gatccgcgaa cagagacgga cggtgctgtt tagcggtgac acctatcaga cggacgcgct
    73621 ctggcaagcg gccggggatg tggatgcatt gcaggcggca tttatcgaat gttcgttttc
    73681 cgacgagatg gccgaattgg cacgagtggc gaaacacctc acgccggcat tgctggccga
    73741 ggagtttgcc aagcttgcga aaccggaggt gccggtctat gcctaccatt tgaagccgcg
    73801 gtttcgagca cagatccggc aggaactcgg aggactcggc attcgacatt tgaccgcgct
    73861 tgaagagggc caaacccttg tactataggt gagcagagat ggcttggttt aaaaaaggaa
    73921 aaactgagga agcagagcca cccaaacgct cgaaaacggc ggaggggatg tggctgaagt
    73981 gtaatcattg tcgggagatc gtgtatcgca aggaggtcga tcgtaacaat aaggtctgcc
    74041 ccaagtgcga ttatcacttt cccatctcgg tcatcgaacg catcaatctg ttggttgatc
    74101 tcggcacgtt caaagagtgg gatcccgagc tcgagccgca ggacccgctg cagtttcagg
    74161 acacccgcag ctataaagac cggattaagg cacagcagga gaagacgggt cggaaggacg
    74221 ccatggtcat cggccagggt gtcatcaacg gacgaaaggt cgccctttgc gtgttcgatt
    74281 tcgggtttat gggcggcagt atgggctctg tggtgggtga aaaaatctgc cgcgcagtcg
    74341 atcgcgcctt ggaagcgcgg atgccattga tcctcgtgac ggcttccggc ggagcccgta
    74401 tgcaggaggg gatcctgtcg ctgatgcaaa tggcgaaaac gtccgcagcg gtcgcgaaac
    74461 tgggcgaggc caaactgccg tttatctcga ttctggccga tccgaccttc ggcggcgtga
    74521 cggcaagtat cgcgatgctc ggagacgtga ttattgccga gcccaaagcg ctgatcggat
    74581 tcgccggccc gcgcgtcatt gagcagacga tcaagcaaca attgccggac cagttccagc
    74641 gggcggagtt tttgctcgac catgggatga tcgatatgat cgtcgagcgc aagcagctga
    74701 aagaggcggt cagcaccctg gtcggtcatt tctaacggga tgcggacaca gtctgccggc
    74761 aatgttcccg ctctgtccgc tcgcgtgagg taccagcacc gttcggtctc gctccgtgtt
    74821 cgccacggcc ttcccggacg atcatttccg catcctggtg agcttcgacg tcaacatgca
    74881 atgtgagtct cccgtggccc cgatgaccta tcccgctacc gtgcaatttt tgtatggctt
    74941 gcaactgcac gggattaaat taggtctcga aacgattcgc acgctgctcg cgcgggtagg
    75001 cgatccgcat cgtcagtacc ccgtgttgca catcggcgga acaaacggca aaggctcgac
    75061 tgccgcgatg accgcgtcga ttttgcaggt ctccggccat cgggtgggac tgtatacctc
    75121 gccgcatttg atcgactttc gcgagcgcat tcgcgtcaac ggcgagatga ttcccgagtc
    75181 gcgcgtcatc catggcgtcg aattgttgcg cgcggcttcc gcgccggatc tggctccgac
    75241 attttttgag ttcaccacgg cgctcgcgtt tcaccatttc gcggaatgtc aggtggatgt
    75301 cgttgtgctc gaagtgggct tgggaggacg ctttgacgcc acgaatgtcg tggagccgct
    75361 cgcagccgcc atcaccacga tcggactcga tcatgaggcc tatctgggct cgacgattga
    75421 agctattgcg atggaaaaag ccgggatcat caagccggga gtgccggtag tgctgggtcg
    75481 aatcggtgag ccgggttctc gagtaatcga agagcgcgcc tcgacagtag gcgctcccgt
    75541 ccttcgtctc gatcgggact tccgctgtga aggatcctcg ccggctgact gccgatacac
    75601 aggtttcgga ctgcggctgg agcacctcag ttgtccctta cagggtcgat ttcagatcga
    75661 caatgtggcc tgctccctgg cgctgatcga gctggctcat gagcgcggtg tcacagtgac
    75721 ggagacgtcc gtacgagcag ggctgcagca ggtggcatgg gaggggcggc tggagattgt
    75781 cggccaggag ccgacggtga tggtagacgg ggcccacaat ccggcggctg cggcggtcct
    75841 cgctgaatat ctatccgaat ggaagcgtgt cagccccgcc gcgcggctct gtctaatcgt
    75901 gggaatgatg cgtgataagc atccgcgcga atttctggcg ccattgctgc cgttgatcga
    75961 tacgctgatt ctgactcagg cggaccttcc gcgtgccgcg accgggtcgg aacttcgtct
    76021 gttgcttgag catgacgcac cgtttgcgca agttgcgacg accccttcgg atgccttggc
    76081 catggccaag cattcagccg ctgcgtccga cgtggtttgt gtcacgggct ccttgatgct
    76141 ggtcggcgag atcaaggccc ttcttcgagg ggattccctc tcgcctgttc gtggttgaga
    76201 tggggcgaga cggttattcg gtttcaacgt ggcagcgcct gatcagccac tttccgtgca
    76261 tcctctccat ttccattctt ttcggtctct ttccgctctt cgcgccctcg gcgtgggggg
    76321 aatcgaccgt caccaccgtt tcaccgacaa accagcctct gacggtcacc gctgagcgca
    76381 tcgatcatct ccaagagcgt gaagtgtatg aggcggatgg atccgtcgtg gtgacccaag
    76441 ggaatttacg gctgaccgcc gatcatgtga cgatcaatgc cttgcctggc acgttgacgg
    76501 caacgggccg tgtgcatttc tgggacgcga gttccgatct caaatccgaa cggctggaat
    76561 tgaatgtgaa taccgaagcc ggcatcgtcg ccaacgggtc gatgtttatc cggccaagca
    76621 attcattttt taccggccgc agtatccgaa ggttgtcgga ggatcactac cgcatcaagg
    76681 aaggtacgtt taccaattgc gatgccaagg agggcgaagt gccggcctgg cgatttacct
    76741 tcgaggatct cgatgtgaat gcgggagaga gcatcgggat gaagcgggcg tggctctgtg
    76801 cgaacgatac gccgatcatt ccggtaccaa cactgacgta cccgctgagc aaccggcata
    76861 gcgggtttct cattccgacg cccggctacg ataaccggtt cggcttgcac tatcagcagg
    76921 ggtacttctg ggcaatcaac cccagccagg atctcactat cgcgccgtcg tactacaata
    76981 atctggggta cggcagcgat ttcacctatc gctattatct ggaccggcga tcgagcgggc
    77041 agtggtttgc cagtttcctg cagcagacca agttgccgaa tgtgtcggga gtggatcagg
    77101 ttagttcgga tgagcggcgt ctgcgcggat taatcagcgg ccagcatgtc cagcaggtnn
    77161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    77221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnngt tcggatgagc ggcgtctgcg
    77281 cggattaatc agcggccagc atgtccagca ggtgacggac acgctcctgg tgcgcgggca
    77341 ggcctcgttc gtctcagacc ggcaatacct ccagcaattg agcaattcag gtacgcaacg
    77401 ggcctcgccc agcggtgaat cgacgttgct ggccacgcag cggctaccgt acggaagcgc
    77461 ctattttctc ggacaatatc tgcagccgtt gaattccggc ggcccagaca cctttcagcg
    77521 ccttcccgag gtggggtacg tcctgccgaa cacatcgcca ttcgggatgc cggttctcct
    77581 gaacctggac acgaactttg tgaacttcta tcgcgaacag ggtttcgcgg tgaatcgcat
    77641 ggacttcatg ccgggggtaa ccacagaggt gatggacgtg gggcatgtga ttggcttgac
    77701 gccgcatgtc aaatttaagg aggtctatta cacgcgcggg attcaggagg ccagtccgct
    77761 gcatcgcgag acattctggg ccgcaatgga tgcgacctcg aagttgagcc ggcggtacac
    77821 aggcggggaa ggaggaagct tccttcacac gatcgaacca agcgtgattt atgaatacgt
    77881 cccgggcagc gatcaaagca agattgcgca gatcgatcag atcgacgaca ttccgaagaa
    77941 aaatttgctg acctatgcgc tgcgtacgaa gttcctggag caacagctca atgggcagag
    78001 tttcaattgg ttggatctga ccgtggcgca aagttatcac gtaggagcgg tgcagacgcg
    78061 ggcgcgagaa tttactcccg gcgtattgcc gttcctgggg tcgctgacac agcctttgca
    78121 gccggcgacg gtagatgtgc agggccggaa gatgtccgat gtgtggatgc gtgcggtgat
    78181 cgggaacacg gcaccggaat tttttcgtcc tcccgctatt aacgaagcac tcggaaagaa
    78241 tgtgacaggc ggacaaatgt tgccgccgac aaattcctat ctacaggtgg atgcgttttt
    78301 ggacccgtat cgggggacgt tcagccagtg gaataccgac ctgcgagtgc agcaatccaa
    78361 ttactggtac gttgaggtcg ggcaacggtt cagtcatgac ggcaatcgag tccgccgcgg
    78421 agatatttgg aatccggttt ccttcaatga agtctatgcc cccaccaagg aaattcaatt
    78481 cgccacggcc ggcggcggat tccggacgcc ctgggggtgg accatcggcg ccaagggata
    78541 ttacgatgtg aaaggcggac gcagcccgga atttgatgtg gtggcgctct atcaaaatcc
    78601 atgtaagtgc tggtcgctcg ggctgtacta cctgcagttc ccggaccgac agagttattc
    78661 cttcatgttc agtatgaccg gcattggctg gacggaaaat ttcggtacga ttgtggctag
    78721 gaccatcctc ggtccgttgc tggtaggaga tcgtgggttg ccctgggccg ctcccggtgg
    78781 tccctatggt cgtgtacaaa atgcgctccc tgttcagtcg atgccaatgg ggcgctatta
    78841 gtgaagcgcc cggttggatt tccatctctc aggagcatcg cccatgatcg aaacgaagcg
    78901 tgcagctgga attcgactca accggcgtac cgttctgacg acctgtcttc tgatgctagc
    78961 catcgccgtg caggaaattt acccgtcagg gctttctgcc acagagcaca tggcacatct
    79021 cgaacgggcc gcggtgtttt tgaaggcggg agattatcga caagcgctgg aggcgtgtca
    79081 ggcagaagtg aaggataggc cgtccgctcg gagttatctg tatctgacct atgcctatca
    79141 tgctcttgat ggctacttgc agtatttagc aaacaccgat caatgggttc gagtcgaaca
    79201 tctctatgtg aatctgtcta caggacgcgt ggaggatttg ctcgatccgc cggatgtcct
    79261 ggctcggata gccaaagagg tgattcagca ggctgcgcaa cggcaggcgg atgtcaccgc
    79321 agctctagcc gggcgcttgg acgagactct ggtcaaacaa ctgtggcagc agcaaaccgc
    79381 atggagacag gcccgaccgg atgattggtg gtcggctgca ccgccgcagt ggcaatgggc
    79441 ggcaccgtga tttgactctc cgcaaaacca tgttatagga tgaccaacag tacctgaagc
    79501 cgcttcagga cgtgaaccag acagcagttt gtgagtagag aaggaggcaa ttgtggcagg
    79561 cgatgcgttg aaagcgactg atgcaacgtg ggatgaagat gtcatgaagg catccgaatt
    79621 ggtcatggta gatttttggg cggtgtggtg tggcccctgt cagatggtcg ctccgatcgt
    79681 cgatgaattg gcgacagaat atgctggtaa agtaaaggtt cgtaaactca atactgatga
    79741 aaacccggaa atcgccggcc gttatcaggt catgagcatt ccgaccatct tgttcttcaa
    79801 gaatggtcag gccgtagaac ggctggtcgg tgcgcgtccc aaacgccagt tcaaagagat
    79861 catcgatacg ctccttgctc aacattccgg cgccgcctag cgccagactc tcagcggcat
    79921 gctgaccgag ctgcgcatct cgaatttcgg tgtgatcgag cagctggccg tcacctttgg
    79981 cgccggtttc attgtattta ccggtgaaac cggcgccgga aaatctcttc tcatcgatgc
    80041 tgtgacgctc ctcgtcggag gccgtgcttc cgcagaacac attcgtgcgc aggccgaaga
    80101 agcagagctg gaagcggcct ttcatctgcc accagaacat ccgctccttg cattgttgcg
    80161 caacaaaggc tttgcacggt ccggcgagac cgatattctc attcggcgca tcatctcacg
    80221 cacaggtcgc aatcgaacct atctaaacgg caacctgtgc cctgtccatc tcctggaaga
    80281 actggggggc gccctcgtgg atgtgcacgg acaacacgag cagcaatcct tgttgtcacc
    80341 ttccgctcag atggatgcgc tggatgcgtt cggcggcttt cagccgctcc ggcaggaata
    80401 tcagcatgcg tatcgggatt ggcaggaccg ggtgggtgat ctggaaacgc tcactgctca
    80461 gattgcacag cgtcgggagc gggaggacct cctcagattt caatttcagg aaatgacgga
    80521 cgcggggatt gaggcaggcg aagatgcacg actcgaacag gagcgtccac ggctgatgca
    80581 cagccagcag ctcggagaat tgtccgacca gctccatgag ctgctctacg cgggtgacca
    80641 gggagtctta agtctattgg ctggtgccag gaagctgctt gccaaaatgg agtcgctcga
    80701 cgccacgact gtcgagtgga tcaagacgat ggatgaagcg gtcgtcccgt taaaagatct
    80761 tgctgaccag gtccgccgct accgtgatca tgtggaggcc aatcccagcc gattgctgga
    80821 gatcgagcag cggctggatc ggttgcatcg gctcgcgaaa aaatacggcg gttcgttgga
    80881 tgcgatgctg gcttggcagg attctctgcg tgcacagctg gctgaattag accatgcgga
    80941 gacccatctg caggaacgta ctcgtgcggt cgagcaggct gtactcagcc tacgcgatgt
    81001 ggcggaccgt ctatctcgta agcggctcga cgcggccaaa aaaataacgg cccaggtgat
    81061 gaaggaactg ggggggctcc gaatggagcg gactcgtttc agcgtggagg tctcgcgtct
    81121 gtccggcgac gcgccctacg gtcagacagg acaggacacg gtggagttta tgttctccgc
    81181 aaatccaggg gaaccgctca aaccgctggc aaaggtggct tcgggcggag aattgtcgcg
    81241 tgtcatgttg gcattaaaaa cgattttggc cgagagcgat caggtgcctg tcctgatttt
    81301 tgatgaagtc gatgccggtg tcgggggcgc cgttgccgag gtaatggggg tgagactgag
    81361 gagtctcagt cggcaccatc aggtgttgtg cgttacccat cttcctcagg tgggctctca
    81421 agcgcatgcg cattatctcg tggaaaaatg ggttcggcag aatcgaacca tgacacaagt
    81481 ccgcctgctg gacctggatg aacgggaaga agaagtggcg cggatgttgg ccggcgtgac
    81541 ggtgaccaag aaggcgcgcg cggcggcggc tgaaatgatt gcgagcgcga aggaccggca
    81601 gtaacggccg gttagttcgt gggcgaggtt ttggcgatcg cgagtgccgg cagggaagac
    81661 ttacattctc gcaccacgtg cgcgaagagc tcggtcaact tgggatcgaa gtaggtatcg
    81721 gcttgcagca gaatctgtcg aatggcttca tcgatggatg tcggctggtg tcccggcata
    81781 tccaccgtca ggttgtcgaa cgcctgggcg atggcgacaa tccgtgccaa aagcgggatg
    81841 ccttcgcctt ctagaccgtg tggattgccc acaccgtcga agcgctcctg atgatacgcc
    81901 acgatctgtc cgacctccgc ttggaatcca agtggcagca gcatccgggc ccctgtctca
    81961 aagcactctt tcccatgagt gttcgtcttc aggctctcat catcatccgc tgaatacttg
    82021 tagttggaga ggctgatctt gccgatatca tgtagaaatg ctcccagcgc cagagccttt
    82081 tggtcgggca ggggcagcgt gagctggttg gcgagaagtg aggcatagaa actcacgcgg
    82141 ctgcaatggt tgagcagttg ccggtccttg gcttcgagca ggtcggataa cagtgggatg
    82201 agcgctgtga cgtccgctgc agttccggtc gcgtccgttg aggaattgcc gatcgcgaag
    82261 tacttcgatt gcagatcttt ccacgcttct gccgcttcct gttcggtgcc ccacaaggcc
    82321 gtcgatgttt tcaggaacga tcgtaagtag tccagtcgct gtttcttttc cagggtctgg
    82381 ttgatcaggg tgatcagctc cgtgacgttg aatggcttga gcaggtagcc ggccgcgccg
    82441 tgccggatgc cttccatggc cgatttcaag ctgccatagc ctgtaatgat gatgacttct
    82501 atgtctgcgt aatcctgctt gatgtcctgc aggaggtcga taccttgacg gtcgggtagt
    82561 ttctgatcca gggtgatgag atcgatgtgc tggtccttca gaacccggag cgcggatttc
    82621 gcattgtcgg cagagtggat cgtgaagaag gggcgaagaa taactttcag cgcgtctcgc
    82681 gggcctgttt cgtcgtcaac gaccaggacc gacggtttta tgctgatctg ttcagttgat
    82741 gcctgagttc ccatccagag cgctcccggt gcattgcgaa cttcaggaaa gataaaacgc
    82801 aaaacctgta ccgtctacgt ataccgtaaa cggtcaatat atagcaggtc taactatttc
    82861 aggccacaag atatttgagc ggggcgaccg gcacgtgaaa aagtatgaga cacatgccga
    82921 gactcttgtg ccagtctgtg tcattcctga ggcagtgaag cctcggcatt tcccccgccg
    82981 ctatcaggtc ggctgatgcc caatgtgtcc atgcgatatt tcagcatgcg acggctaatg
    83041 cccagcatcg tggccgcatg agtttgtacg tatgtcgtcc gcttgagcgc atctaaaata
    83101 atttcacgct cgaattccat gacagccttt tccagggata atcgtccggc gagggtgtca
    83161 tcccgaaggg acgatgagcg cgtatcagtc cggagaatat tcgggagatg ctccggggtg
    83221 atcaccgtgg agcccttcga ccagatgaag gcttgctcga tgatattttc catctcgcgc
    83281 acgttgcctg gccacggata atgtgaaatc aattcgaggg cgtctttggt gaattcctga
    83341 gacggtcgtt tctcttcctc aatgcgtttc gaaagaaaat gcttcgcgag aagggcaatg
    83401 tcctcgccgc gctcacgtaa tggcggaagg tacagcgcaa tcacgttgat acggtaatac
    83461 aagtcctcgc ggaactggtt tttcctgacc atctcatcaa ggttcttgtt ggtggccgcg
    83521 acgatccgga catcgacctt gatggattgc accccgccga cccgcgtaaa ttcccgttcc
    83581 tgcagtaccc gcaagagctt ggcttgtgtt gcgggactga gatcgccgat ttcatccagg
    83641 aacagcgtgc ccgtatgcgc taattcgaac tgtcccactc gtcgtgccgt ggcatcggtg
    83701 aacgaaccct tttcatggcc gaacagctcg ctttcgatga gcgtttcagg caacgccgcg
    83761 caattgaggg cgacgaacgg gcgttcccgc ctagcgctgt tgtaatggat ggctttggcg
    83821 accagttctt ttccagtccc gctttcaccg gtgaccagga cggtggtgcg gctatctgcc
    83881 acttgttcga ttttggcgta gatttcctgc atcgcggggc ttttgccgat gaggttgtgg
    83941 aaggcatagc gctgcacaac ctgagcgcgc aattgccgga cctcttgttc cagttcctgc
    84001 ttacccaagg ttcgttcgat gacaatttga agttcctcga cgtcgaacgg tttggataga
    84061 tagtcggcgg ctccgagctt catcgcatcg acagcggttt tcactgcctt ggtgccggtc
    84121 agcataatca ccggtacggc tcgattctcg gttcgcatgg tctgaagcgc ggacagaccg
    84181 tccgctcccg gtaggatgac gtccaggagg accaggtccg gggcatcgtg tttaaaactg
    84241 cgaaggccct cagcagcatc cgccgcttca aaaatttcat acgtgggttc taggaccgtt
    84301 ctcagcgagg cccggacacg cggctcatcg tcgacaagta ggactcgttt tttcatatta
    84361 ctcccgtgct gctgagactg tgggcgctga atcgggaaca ggaagattca cggagaacgt
    84421 ggagcccgct cctaggcggc tttcgactat cagggtgcca ccgtgctctc gaacaatttg
    84481 atgcgcggtg gtgagcccga ggccggctcc ttcactggca ctgttggaat gtttggtgct
    84541 gaaaaatgga tcgaaaatgt gctcgagatg atcgggcgcg ataccacatc cttcatcctc
    84601 gacctgcaat tgtacccatg gggggcggcc ggcttcggac aggagtcgcg tatgaacccg
    84661 aatgatgccg ttgccattgg gcattgcatc cagagcattc aggagcagat tcaacaacac
    84721 ctgtttgatt tgctggcgat cgagcaagag cagaggaagc tgcggcgaca ggtgcgtctg
    84781 aacctgaatt ccccgatgcg cggcgctcga tgagatgaag ccgatacaag aggcgacgag
    84841 atcgttcagg tccacttccg tggggcgcgg cgtcatgtaa ctggcatagt cgagaatctc
    84901 atgaagcagt cgttcgatgc gatggatgtc ttcgatagcc agtttgctga attctttgat
    84961 gaagacggga tcctgctgtc gctggggggc cagctggacg aatgttttga tggacgtgag
    85021 cgggtttcga atttcatggg caaacccgcc ggccatgatt tcgagagaac ggagtcgatc
    85081 cgtccgtctc atcaatgtgg atgagcggcg gaggtcgtct tgcgtcaggt aatgatcgag
    85141 gctattgcct gcgatgtggg taatcgcgtc aacgatggcg agcagttctt cgccgacctg
    85201 cgctttcgtg tcgagaggcc ccaggatgca gatcccgagc agtcgccctt tggttcgtag
    85261 tccgaggcac aggctcgcgc gggccgtcgc catcgccaac ccaagcggtt tagagggatt
    85321 ctcgctccca tgacatacgt agggtttggc ggagagacct gcaacgagcg ggtgatcacc
    85381 cgtcaaagtc gatggtaatg aagagggatg gttgtgtcca tacgatgcaa ggagacgata
    85441 ccgttcacct gtagactcgc gaatccacag ggctacttcg ggcaaccgag tgtattgcga
    85501 aagagccgtc acaatcgaat gtccgagaca tgacaggtct cgtgccgatc ccagggtttc
    85561 agcgaagtca cggatcagtc tgacaatgtc cgtggaagct gaaaggacgg gcatctgccg
    85621 gatgttggcg tggagcgtca tagtcccgtg ggaggaatat cattccggac accaggtttc
    85681 cccaggtgtc gcctgactca ctgcatgttt tatgctagtg agtgaagtat atatgcgctc
    85741 tattgtttca gctagaggaa tccggttttt cagcggcggc gagcagaatc tgtccggcga
    85801 gagtacgaac aagtctaggt gtaagcggtg tgaagcgtgc gatcagtgtg gtcagactct
    85861 cttcctcaaa cgtgtgtaat tgccctgtac gtagtgctac cgcgcactgt cccatacggt
    85921 gcaaggccaa gcgaggcgct cctgaaaatg cgtcgatgcc gatttcgtgt aaggccggtc
    85981 tgtacaggcg agccagatct gtggcggggg taaaagcctt caggataagt ttcccgccgg
    86041 gccgaagcac gcggaagaat tctcggagcg agtgcacggg tgagcgtaca aagctcaacg
    86101 agaaatttgc caccacacga tcgaatgagc agtccgcaaa tggcagcgcg tctgccgagc
    86161 gaccgaggat ccattgctgg gtgacgggcg tcggtgcaga gatccgtcct gaaaagagct
    86221 cgtcaaggtg ttgcagcgct tcttttgtcg aggctcgggc agcatgcagt gaagcagagg
    86281 aaaaatccag cccgacatat cggagtgggt ggttatgatg ccaggtttga gcgcgcaggc
    86341 gatatgaaag attgagtagc agcaaccgag cgaaggaatg catgccgcat ccgatatcca
    86401 ggagggcgac attgccgtcg agaggctgca agagttgata gagttgatcg atagactgcc
    86461 aatgtgccgg cagttcatcc agggcccggg tgagttccgt gtgtgccgtc caaagtcgtt
    86521 cgttactcgt cgtgccgatg gcgtgtttat gacgaagctg atcgcgttcg aaccgggcac
    86581 gtgtggatgt tgcaagcaag agcgacggaa gcatgaccct tcctggttcg tgaagtgcct
    86641 gtcccgcttg gcagaggtgt gacacctgtt gccaacttgc gcgtagagtc gaaggtggct
    86701 gagggcctga tgtcaaggta gacgacggca acagtacttt cctgccttta acgccaagcc
    86761 gggagaggag gtcattcacg agaggttgag gaggaggcgg gatcgagcag tcagggccat
    86821 cttgtccgcc ggtgaggacg actacctccg tttcacagtg ggccagttca ttgtgcagga
    86881 ccctgacatc cgtatactgc gcggcaactg cgtcggccaa aaaatggtcg atgtcgagcg
    86941 gaatcccgag taaatttccc aggcccaggc acgtcccgtt taggtgttcc tgtaacagat
    87001 ctcggtggtg gagggtttgc aggcactgtc cgaggtcgag tgtcggattg agaagcagaa
    87061 ggcgccgaat ccgcctgtgc caatcctgtc tgcgcaatgc gattcgagcg ggaaggtccg
    87121 gcgccaatat cgtcaggggt ctttccggcc agtgttcctg cacgaaggtc aacactgtat
    87181 caaggtcgtc ctcaagagag gtgaatgtgg tttgcgaagg gtctccgtcg ctgaggccaa
    87241 tatggcggct gtgatcgtaa cgcaccacat gaaagccgcg gccagccagc atataagcca
    87301 acgcgacata ggcgtgctgc gtcgtgccgt atccggggca caggagtacc agcggatcat
    87361 gctcgctgcc gcctcctgta gggaagtcat gccgcaacgc aatcgtatag ccttcacggt
    87421 tccgcaccgt gtgtgacacg gtgagaacag gggcatccga cggggtttcg gccagatgct
    87481 gctctgcccg gaattcagcc tccatgatgc tacgcagtct ctgctcttgt gcgggggaca
    87541 gagtatcaaa gcgtataccg atctgctgga ggtgatgtcc cgttgctgcg aggcggagtt
    87601 tcagcctcct ttccgccgaa tcgttccaga gaatctgtgc cgtcagtggc tgttcggcct
    87661 ctggtgcttg ggaggtgccg ggcaccatgg tgatcgactc cagagggttc agatggatga
    87721 cccgtgagtg ttcggtcaag acgacctctg tcggcagttc gatgcaagcc ccgttcagat
    87781 tgagattgat gatcttgccg aacggacgcg atgaggccgc gtcggatcca gttatgtata
    87841 cggggcaaga cacgctcagt cgagcggctt cccgccggtc ttccggcatc tctcgaagtg
    87901 gaaggaggtt ccggtgctgg atcgtttggg ctatgggcag ggggagaatc agtccttcga
    87961 atgtgatctg cggggacccc tcctgcaggc cctcgagcaa ggatctgagt acattgcgct
    88021 catgttcgac ggcgagagca aaggaaatca caaaatcctt aatggccggc aacgacaatt
    88081 cggtggatgc ggagggccgc tcatgcacga ctccttgcag ttcaaggaag ctgaccgggg
    88141 tcttgatcac gacataggcg ggctgcagat ggatcgaact ttccattcct cggatcgtaa
    88201 ggagcgcccc ttccgtactc atattgcgta acagcccgcg tagggtcgtg cctccgatcg
    88261 acaattgaac agggagggaa aacggcttgc gctctgaccg gcgacgttca gggcgttgcg
    88321 aggtgtctct cccaggcttg tgaatgtcgg ttgggggcgg cgagattgtt gttgccggtg
    88381 ttccagtcag ggagaagtct tccgaggcgg ggatgcgaac tgtgatggct aatccggatt
    88441 ctggtgtgtg ttcgacttcg atggcacccc ggtgtacctg aacgatgcga tgtgcctgga
    88501 ataaactcac tgccgagcga tcgtggcctg attggctgtc cggaggcaga cggagtgagc
    88561 tggcacttcc ccggatcgta aagctcgcat acgtacgaag cggccgggaa agcgatgcca
    88621 cctcctgccc aggacttcct gaagtctcca cggcgagtac tgctgtgtgc aaggttaagc
    88681 tgggacgtgt gttgtcaggt gtggatcggc aggcatagct gagcaagata tgggtgaggt
    88741 cttccaggtc cgcacgcgaa ccgagaatga gtggaaggtt cgccgcaaac tgagtggtga
    88801 ggagaaattg ggaatcttcc gtctcaccgt gcgtcgtctg ggcaactgtc tggagaacct
    88861 cattcagatc aagaagaatc aattctgtcg gcggggcatg gatcgcttcg gccaattgat
    88921 gtcccagctg gctcgcttgc gaagcctgag cgaccatcgt ttcaacatgt tgctcgaacc
    88981 ggctgtgttg gatcgacgtc agcaatcgtt gtgagtcctg aagaagggac gtaaggggtt
    89041 gctgcagttg gcgggagacc cgggctgcct cgcgggagag ggtgagttga cgatcggtct
    89101 cctggagacg agactccagt tccgccaacc ggttctgttg ggccttttgc tgggatagat
    89161 cccgcagcaa tccgaccgtt cccaagtatc gattcgtgga gtcgaaaagg cctttcgctg
    89221 tgacttcgac gatgatgggt acggatggag cctcggggag ggctttgcgg tagagcgtga
    89281 gttccacccg gcgtgtcgaa cggctgcctg cccggcgctc attcaatcga aaacgcgcgg
    89341 ttggttcctg ttgaggagga agcaggagag agtagtgccg accggcgagt tcctcagccg
    89401 tgtatccaag cattgcggtg acggttggac tcacatacac gaaacgaccg tccgcatcga
    89461 gttcgtacaa gagatcactc aacgtttcga tcacgcggag gtggcgttga aacgtatggt
    89521 ccagcttcat ttgcaggtcg cgcttttcga gggcttcctg tacggaaaag aggagctccg
    89581 tgagaaatcc gggcgatcgt ttgaagagca aaaagtcggc tccgtgctgg agggcttgaa
    89641 cggccgtgtg tgagtcactc tcgttcgtct gaagaaggat tgccgcatag ggcgcattgc
    89701 gacgaaggcg cgcgagcaga tcgagacctc gttccggact cagatcctga tcaatgagaa
    89761 tgatttgcca gtcgccctgg cgggtgaatg caagggcatc ttcggacgag tacccggctt
    89821 cgatgcgaca gcccacaaaa aagctccgca agctggtggt caccaacttg atttcgtcgg
    89881 cattctcatt gatgaggagg atatgcagcg agggttcggg caaggacatg gaagatctca
    89941 tggtcttcat gcaggggcgc gttcagcgtg ccccgaggct gtgagtgccc cggggaatgc
    90001 accaccgtac agtgatgaac atgctctccc tctcaggcgg acaaatctgt ccttccccag
    90061 ctgattggac tgcatgattg gttcaatatc atacaccttc ttgagaatcc cagtccgccg
    90121 cccgaggggg cggttccact tcggtagggg aggaacgatt gaaatctgag cgactgacga
    90181 aagctaggga gaccctgaat tggagaagtg ttccgattgg aacaggtttt agtatgagtc
    90241 ggtgcggagc ctggattggg ctgaacccac cacagccgcg tcctgtggtg ggtgcctgac
    90301 agtgttggct agtgggccgc ggccgtggtc gacgactgct ggcaggcgcc aggcgtcata
    90361 tagagcagat agttacccat gccatgttgg atgttagggt tttgcagaag atgatggtga
    90421 accatcacca tttcgtagtc atcctgcttc gtcaccgaaa atcctttgct atcccgataa
    90481 acctgatgcg gtcgaaagtc ccggaatgta ccgtcggcat cgacctcggg gacggtgcgt
    90541 agcagggtct cttttgaagt cttattctcg agcgccacca tgagaagttc gtcatgccca
    90601 tggggatagg caaatttgac gcagccatcc atgttgaatt tcagcggcgc cgaaaggacc
    90661 gagactcccg acttgatttc gatcccttcg tccgtctggt ccgggccccg ttgggcgaac
    90721 ttgctgtagc acacaatgtt cacgcctacc tggtagacgt ccatctcctg caccttcgcc
    90781 cctttgggag cgacgtacat ggtgaagcgc gccatcacgt ctttcgtcgg cggggccttg
    90841 tgataaaagg ccacaacgga catgagattt tggcctttgc ccaactttac tccatatccg
    90901 tccgggaaac gggcttccgt catctccagt ccggcccccg caaaaaacaa cggctcgcca
    90961 tcgcatgaga cgctgggttt gtcattgttc aacatgagga tgtgatggag ataatttttc
    91021 ggaaggggtt tgccatcttt cgtgaacacc tcggatttgt agccgatcat gtaggtgtcc
    91081 tctggcagtt ggaacacctt cttcggcatg ctggaggcta gatcgccatc atggccggtc
    91141 ggcagatcga cggggccgaa tgtgagcgtg acggtctgct catcgatcgt cagtttcgtc
    91201 tcccccaaac tcggcatggt aggaatagcg tgatgatcat gtccgccgtc ggcatacgcc
    91261 aaactcgtga cgcccaagaa catgactact aacagaagcg cacgattcat aggcccctcc
    91321 tcgttgtaac agaccggccg tccatgagtg tgtgtaaagc gttgtagggc gtgaccgcct
    91381 gtccgttaag gagctgtcgg aggcggggtg agtcgtttcc acaggtagct gccgccatgt
    91441 tgccggggcg ggatattgtc tctggtgccg acacgcacat accaccagat gcctttggct
    91501 tccgtgccat cctctgagag aacgacttca aaggcaccct cgcgatcgtt tcccgtttgt
    91561 ttccacgtgc cctgccagcg tcgatcgttg aagctggtgg tggaaaactg tccgccttgc
    91621 cacgtgtagg gaccggtgcc ctgggcattc agcgtggcga cgtatttctt attatcttcg
    91681 atttccgtga cttcccattc accacttaag tcgacgccgt tcgggacggc cggctgcgca
    91741 tccgaggcgc gatgaagcag tgccgcgccg ttggccgcgg tctgttccgt tccgctgtca
    91801 tgatggcgtg tcgattcatg ccaggccacc agaatccacc ggccgttccg ttgctccagc
    91861 actccggttt cacgcaggtg gagcaccatg cgttgagcga gatccgccgg atcgctgtag
    91921 cggatgtagt ctaattccat tgcgaaccag gccacatctt tgttgttcca catgcgcaga
    91981 tcggtgatcg gaatttccag tttgaccacc gaatcaaact cgctacgcat atcggccgcc
    92041 agatccgacc atccgatgta tttgcgtccg tcaatcgtgt acccgatggc atccacgtcg
    92101 tgtgacatat atttggacat ggtggccaga tcacgttcgg cattggcctg aacaagcctc
    92161 cgcagggtgg tctccgcatc gtggggttcc ccggctcgcg ccgtcggaag gtacagcatt
    92221 cccaagagcg gaccaagcag gagccaggtt cggactcgca gactgagtgg acgaaagtaa
    92281 tgcgattcca tgttcattag aagtgagcta tggaggcctc tgaggcctta cctcgtggat
    92341 gtatggtttt gaggctacct ggtgccttga ggcactgtca atggatattt ccctgatcgg
    92401 ggagactggt catggcgcag gccacgacgg tgatgttgtc gatgccgccg gtatcaatcg
    92461 ccgcttggat cagggcctgg gtcgtgaggg agggactgtc tctatgcgac tgtgcaattt
    92521 tgagtatgtg ttcgtccggc agcattttgg tgagcccgtc ggaacagagc aacagcacat
    92581 cgccgacgaa gacgtcgaca ggaaagagat cgatctgcag gactggttca agcccgatcg
    92641 cacgggtcag cacgtggcgg tccgggtggc gggcagcctg ctcaggcgtg aggcggccct
    92701 cgcgcacata gtcgtcaatg agggtgtggt ctcgggtcaa ctgcgtgatg cgtcccgccc
    92761 ggacgagata cgcccgactg tcgccgacat tgagcacaag gagtcgaggg gcgggcagag
    92821 gcatcagatg ggccatcacc agcgtcgttc ccatcccgta gacagagggg tgacgatcag
    92881 cataggcgcg cacggcatca tgagcctgtt ccgccatagt tgtgaggcga aaagactgct
    92941 gctcggtatg gtcctcgtcg aggttgtcgg aattgcgaat gaggcttggt gaaaaatcgg
    93001 cgagcgtgtc catgacgatc cggctggcca cgtctcctcc gggatgtcct cccatgccat
    93061 cagcgactgc ccacaggcgg cgccggttgt cgacgagaaa ggcatcctga ttggtcgagc
    93121 ggaccagtcc acggtccgtc tgcccgtagc ctgtccagtc ccacttgcct tgagcgagcg
    93181 ccacgttatc cgaccagacc gagtgactga ggcccgtatc gcaagaccag ccgttcgtac
    93241 aggcaggctg cgaggggctc caggttttga gtgtcggctg cattataacg gaccagctga
    93301 tccagggcct cgtcgtgacc tgcgcggtaa tggtgccaca atcgaacggc ttccaatcca
    93361 tcgagctgca gcaggtctga ttcccgtgca atgtccaact ctcgttcgat ggacttcaag
    93421 ccgccttgca agccgacgcg tcgggcggca aaacagagat cgaaatgagg gatcgccacg
    93481 cgcaagccgt gaaagcaggt ttgcagatag gggatatcga agaccgttcc aaaaaatgtg
    93541 atgagcaggt cggcttgatc gagttcctct tgaatggcct ctagagtaag atcctggcca
    93601 tggatcaacg tccgcatgcg cccctgacga tgaagtccga cgatggtcac ctgtccctcg
    93661 cgggccgaga gtcctgtggt ttcaatatcg aggtagagcg cgcgggcccc gaaggtctga
    93721 aacaatcgcc aatgatcccg ggtgtggagg caatctgcga aataccgggg gttatgcagg
    93781 tcgaggtggt cctgtgcaag ggccagctcg gcgtcgtagg cagctttacg cgccggcgcg
    93841 ataccggtca ggtgggcttc ccgccggaag gtcgcccaat cggcgatgcc gctttcccac
    93901 agacgtcgct cggtcgatgg cccgatacct tttaaatgga caaacgtgga tgtcagcata
    93961 gaagcggccg ggattgtaac cttgatttca ggggataaac aagttagagt ccgcgactgg
    94021 tgcggagttt cgtcatttgg tgttgcgcac agtatcacgg tgtgaatgag ggatcatgac
    94081 cacgaacggc acgatgaaac gaattcgaat caaggtcggc ggcctccaac tggaggccga
    94141 gttgaagggg acgcgaacgg ccgaggaact gtatcgagcc ttgccggcgg aagggccgtt
    94201 gaatgtgtgg ggcgaagagt tctattttaa aattcccggc gtgaaagatc atcgcgaaac
    94261 ggcgacgacg caagtcaaaa tcggcgacgt ggcattctgg ggagccggcc aggttctggc
    94321 gatctttttt ggccgcacgc cgatgagcat gggcgccgac cctgtgcctg ccgaccgggt
    94381 gaacgttgtg gggcgggtgt tgggtgatgc ggcgacatta cggcaggcca tgaacgccag
    94441 tatgatccgg gtggaacgaa tcgagccggc acaaccggtc gggtagggtt cagcgatgaa
    94501 ggcgaacggg gagcgattgc catgagattg gcgaaagagc gcgtgcatca tatggctgat
    94561 tcggtagtcg cacgactgca ggagttgaat tttctcgagg tgaccggaga tcgaaaggct
    94621 cttcgcgaag tgttggaaca cacgatgacg gaagagctga tggtcgaaga ccgcctcaat
    94681 gccgaagtgc gtcggatgat gcagccatat gaacgccaga tcgagcaagg gcaggtcgac
    94741 tatcaaaaga tgttcaccat gatcaaacag aaactggtgc gtgagcgcgg gatcatctta
    94801 tgagtggccg tgccactcga gacgggagcc gtaatcgtga tcagtgatga caaagccagc
    94861 caccttgccc acctgatact gggcacgtta aagaaaagcc ctcagtgcag gctgaccgaa
    94921 gacgacggca aggtcttgag agagatcaaa cgcgtggtcg ctgctgaact cgccctggac
    94981 gcggagattg ataaaaaagt gcgggcgaaa ctggcgtcct acacgaagca gatcgtggag
    95041 ggcagtcccg aatgggacgt catgtatcga aaaacgtccg aagaagaaca gaaaaaacgc
    95101 gtcaagccct aatcacgctg gcgaatgata tgaacgaggt ggcgcgatga gagtgagtcg
    95161 ctggatagcc ctggtagtgg tggtgctgtc gtgttcggcc tgtgctcatg aaaagccgaa
    95221 accgctcgtg cctctcgagc tggcctacgg ggcgaaggcg gatgcgaatg cgctgaataa
    95281 tcagggcagg caggcctttc tggccggcca aatggctgag gccaaggact tcttcggaca
    95341 ggtgatcaag atagcgccgg actccggaca ggcgcattac aattacgggt tgacgttgaa
    95401 tgccttgggg caaactgatc aggcccgtca ggaattcatc gaggcggcaa atctggcccc
    95461 cggggacaag gtcatctggg attctccggc attgcgtccc tttggaaatc cggaagtgcc
    95521 caaggggccg gcgagagagc atccctacgg aacgagcagg cctacgatcg gtagcggccc
    95581 gcggtaacgc aaacgatggt ggagaaggag agacgcgtag catggcaagt ggagtagaag
    95641 tcggggcaaa ggcgccggag ttttcccttc cggatcagga cggcaacctc gtgacgctca
    95701 agagtttgaa gggcaaacaa gtcgtgctct atttttatcc caaagacgat acctccggtt
    95761 gcacgaaaga ggcctgcgat tttcgggatt ccctggcggc gatcaagaag accggagcag
    95821 tggtgatcgg ggtcagcaag gacggcaaaa cttctcacca gaagtttatc gccaagtacg
    95881 gattgccgtt tgcgctgttg agcgatgaag atacggcggt cagcacagcc tatgacgtct
    95941 ataaagaaaa aagcatgtac ggccggaaat acatgggcat tgagcgcagt acgtttgtga
    96001 tcgatgcaac gggtcgaatc aaggcctcct tcaggaaggt caaggtgccc ggtcatgtgg
    96061 aagaggtctt ggccgcgttg aaggcctagc ttctgttcgg accacagcga ttgcgtcgtt
    96121 gactcctctg tatcttctat ggatccgctg gaaaaaccat cccatgctct ccgtgcagct
    96181 gcgttgtctc tgatgccggg acttggacac ctgtatatcg gtgaaaagcg cggcgggccg
    96241 ctcctcgcgg ccgggttgtt gctgatcatc ctgtggacga actggtttgc gtttgccctc
    96301 gtgccgttgc tcggcctcgt cctgttctcc atgggggata cctatctcac cgtcagccgc
    96361 gaccgcggat tgttctcctg atcacgcatg tgctgctcac cagagaagac cacccgcacc
    96421 atggcagaag ttgttggtct gggactgcgc atattcggtg tgcttctctg tgccgccctc
    96481 gcactggcga cgaccggcga ggcagccggc aaggtctccg gtaccttgat cctgcacgat
    96541 gcgctgacct tgcccaatca ttcggttcgc atagaagcgc aggtcgctgt gacggccgca
    96601 ggtccgccgt tgagcggtct gatgctgcac ctgcagatcg acggaaaaga cgttgcgacg
    96661 gccaaaacca atgaaggcgg ccgggccgcg ttcgattatc tggcgaaaat gcgaggcact
    96721 aatgtcatca gtgtgtcgat cgatccggat gctcccgttg cggcggaaaa agtcgacgcg
    96781 accctgtgtg tgtgggaacg ccggcgcccg attgtggtgg tcgaattaga cgcgctcatc
    96841 cagcagtctc ccgccccggc aactcctgcc gcatcgcctg ggataggggt aacggatgac
    96901 accgtgccga cgccggttcc ggaggctgcc gaggaactct cccgactgac ccagtactac
    96961 tacaacgtgg tctacgtctc gaacaacgag caggggccga tgggaaatgt ctccagtgga
    97021 caggtgcgcc gctggttgga agcgcatcag tttccggtgg ggttcgtggc aacgccgaca
    97081 tcagggggac tgaacgcgac cctcgatgcg ttgaaacatg acggatggac gacgatgaaa
    97141 tccggcatcg ggcgcacgag gggatttgcg gatatgctgc tgcagcaccg catggaagtc
    97201 gtggtggtgc cggaattacc caagggcgaa ttgcctcgca aagccaaggc tgcgaaggat
    97261 tggaaagagg tgcgaaagaa gttgtaggtg gcgtctggat agccatatgg tcgcagaacg
    97321 cgcacctcag aagatgcatc gttcgatgcg cgcaatctat ggccatccgg acatcacctt
    97381 gcgtgaggca aaggtaaaga ctgagagagc gacggaacgt gcagagaagc gcgcaacgcg
    97441 gcgatggcgg atggtgggaa ggtcattcac tccatccgcg aatcatggta tgttcagccc
    97501 ccaatcaggt gtcatctcat tgaaggagca caagccggta tgttgctaga aggtaaaaag
    97561 ggactgatca tcggtgtggc caataagcac agtatcgcct gggccatcgc gcaggctgcc
    97621 gcgcgggaag gcgcgcagat gttgtttagc tatcagaatg aacgattgcg cgaaaacgtc
    97681 gaagaattgg tccagaccct gccgggcgca tcggcctgcg tgtgtgatgt cggagatgac
    97741 agtcagatcg ccgcgatgat gaaagaagcc gctgagaaac tcgggcggtt ggattttgtt
    97801 gtccattcac tcgcttttgc gccccgcgaa gaactcacgg gggaatttgt gaataccacc
    97861 cgccagggat ttgcgacggc cctcgacgtg agcgcctatt ccctcgtcgc cgtcacgcgg
    97921 gcggcgatgc cgttgatgac ggacggcggt tcagtcgtca cgctgaccta tctcggcagc
    97981 gagcgggtcg tgccgcacta taacgtgatg ggcgtcgcca aagccgcgct tgaagcaacg
    98041 gtgcggtacc ttgcccacga tctaggaccc aagaacatcc gcgtgaatgc cgtctccgcc
    98101 ggaccgatca aaacgctggc ggctcgcgga gtatcgggaa tcagcaaaat ggtcgaccac
    98161 catcgcgcgt tcgcaccgct tcggcgggcg accgagcaag gcgaagtcgg cgacacggcg
    98221 ttgttcctcg tcagtccttt aggccgcggc atcaccggag aggtgatcta cgtcgatggg
    98281 ggataccata ttctcggctc gctggcttcc gtcgactagg aagccgaccg tcctgtccgc
    98341 ccgatcccgg ctgcgcgatg tctcggactc attcgggatg tggtggcgat ggaatcgggc
    98401 ggtgatttct ccgcccattc ttttcttctg cctgttcacc ctcgtcatgg cgggcgcgcc
    98461 accgcctgcc ctctctgccc agctcacggc tcgagaagaa gacggattga tcggtaccgt
    98521 tcagtccgta gaaacgatcg acagtctcgt ctcgcagacc gactactacg atcctcaggg
    98581 gcgtattctc gaacgcattc agggcggcaa ggatacatct cacggcttat ggccgctgcg
    98641 atttacctat gtctatgaca aggagggaag acgtatcgcc gaaatgatcc gtgatgcgca
    98701 aggcgaactc gtgaaggaga ctcgcgcggt ttatgatgcg cagggcaacc gctctgccga
    98761 gttgtcggcg tggggggatg ggaccttcga aaatgtgtcc ttgtatgact acgatgaatt
    98821 gcgacggctc aggcgtggcc tccattacaa tgccgtgcac gtcgtgaatc ggaacctcta
    98881 ttcctatgat ggaggtgggc gtctgttaca ggagcgattc gaacggaatt atcggtacga
    98941 cgcggacgga catcagatgg tcaccacgga tcgattcgac gtggggcacg acgtggcgat
    99001 catctataac gatcgtggac aggtacagca aaagaccgtg tcggatctgc gggggcgtag
    99061 gcaagggcat tcggagtttc gctacgatga gcgaggtagt cagatcgaag agcgcagcta
    99121 tgatgctgcc ggccggctca tggatcgcaa gacataccgg tatgaatacg atacggtcgg
    99181 caactggatt acagagacct ttcaatggtg ggaactgcgt gatggtgagc ctcgaatcaa
    99241 gcaatcgcac gtccgcgagc gtcgaatcac ctaccactaa cgcacttcgt ccggcatgtt
    99301 ccggatgtct caggtccctc cacgaaagac tgtaagcgcc gctcgtctct gcggcgtaaa
    99361 ttttcgacgc ctcgtgtgtg atctcgacgg agggcgatgg tgcggtattc caacctgtgg
    99421 caatgtctcg tgactgtcct gctgttatgc ggcgccggcc aagtagagtg ttgggccggg
    99481 gatactcctc acgcgtcgca cgcacacgga cccttgcgac agtctcccga caatccacga
    99541 tattttgccg atgctgacaa ccggatcgtt tacctcaccg gatcccatac ctgggaaaat
    99601 tttcaggatg tcacgcaggt cttcgactat ccggcctatc tcgatcgtct gacggcgctg
    99661 catcacaatt tcatgcgctt gtgggtcact gaatcgatcc attcggacgg cgggtggctc
    99721 atgaatcctc cccccaatga aaaggatatc gccccgcttc cgtatctgcg gaccgggcca
    99781 ggccttgctc tggatggtgg cccacgattg gatctgtccc gcttcaatcc ggcctacttc
    99841 gaacggcttc gagcgagggt gaaggacgcg gggcagcgcg gtatctatgt ttcggtgatg
    99901 ttctttcaag gcttcagcgt ggtgacgccg ggagggtgga aggcgcatcc gctgaatggt
    99961 cagaacaatg tgaacggcat cgacggtgac gccaacggcg acgagctggg tttggaggtt
   100021 catcgatcgc caggagttcc agtgctccag attcaagaag cctatgtgcg gcacgtgttg
   100081 gagacgctgc acgatctgga caatgtcttg tatgaggtgg tgaacgaggc cacgcccgag
   100141 tcggtcagct ggcaatacca tttcattagc ttcatcaagc gctatgagcg tgagcgaggc
   100201 ttcatggcgc atccggtcgg catgacgttt tttcaactag gagagtttgg cggcggtgac
   100261 aatcgcaccc tgtttgagag cgaggccgac tggatctctc ccggcgggta taccaaatat
   100321 gcgcgaaatc ccccggccac ggatggacgt caggtgcagg tgctggatac ggatcatatc
   100381 cacggcatcg gcggtgatca gcaatatgtc tgggaaagct tcatgcgggg gtataacccc
   100441 atctatatgg atccctttga cgcggtccat gagttaacca tcggcgagcc ggtgctaaac
   100501 gaaccgcaac atgagcgcgc gcgagtggcg atggggcaga cgcgccggtg ggcggacagg
   100561 attaacttga agcgtgtaac tccacaaagc gagctggctt caaccggcta ctgcttggct
   100621 gatcgggggc gtgagtattt gatctatatt cctgccagcg actcggtggc tgagtccggc
   100681 gctgaaaagc ctactcgacc ggtgaccgtc aatctgacgg gcgcaagcgg cgtcttcacc
   100741 gcggagtgga tggaactgga aaccggacgc actaaacaag cagattccct catcggcggc
   100801 agcgagcgca tgcttaccgt gcctttccct gggagcgggc tgctgtatct ccggaagtca
   100861 ggataaagaa tttctcgtca cagcatcaga gaagattgcg ggaaaaggta tcgctgcatt
   100921 tcagtggaag gacgatcgga tgtaatctaa ttccgcatgt gatagctcag caatagattt
   100981 gagtccgaaa gttttttgaa gctcttgacc ggttccattt tgagtgaaga taaagtaatg
   101041 cgtaaattga ctcctctgca cggcgacttt cttgcatatt gcgttgacga ttggaccggt
   101101 ctttggctcc tagtaaaacg gatcaagccc cttcactcaa gcactgacgc cgacaaaatt
   101161 caagctcatg cccttgagat catacgtgac ttaatagagg caggctatat catggcgggt
   101221 gatgtggact ttggcttagg aaaatttagg caatggaatc tgtctgttga caagattatc
   101281 ggccgaattg agcaagagtg gatcgagttg ggtcgcgatc cgacaatatg tgaaattgtg
   101341 tggtttgtca gcacgactga aggggattac gcctttgcca gtgggcagtt ccctgagacg
   101401 ccttctactg aataaccaag atcaaggtgg gggtggaatc ctctagtttg ctccactagc
   101461 tggctcggtt cgggttatgg cgtcagcggt cccgtgatgg ggctgccggg cttggcctcg
   101521 ctcgacgcct cagcgccttc ttgcggcagg atgcggaagt gggtgacggc aaacgaaacg
   101581 gcttgcccca ccgtaaaatt gcagcggcga aactcttctt tgttcatgcg tgagcggaga
   101641 atcaatccgt ccgccgtttc aatttccaac cgatacgcga caccgagaaa ataaatgtgg
   101701 cggagtttgg cctgctgacg gtagcgggtc gcatcttcgg ccaccttcac gtagtagggg
   101761 cggaagccga cctgcaactt ctggccgtcg gaaaatcccg gcgcggggaa ttcgagtgag
   101821 cccacctgca cctgattgcg ccgcacgatg ccttccacga tattcatcga cccgatgaaa
   101881 cgcgcgacga attccgtggc tggttcttcg tagacatcag cgggcgatcc ggcctgctcc
   101941 agcttgcctt tggagaagac gatgatgcgg ccggatactt ccatcgcttc ttcctgatcg
   102001 tgagtgacga agaggctggt gacgttcaga tccgtatgca ggcggatgag ccactcgcgc
   102061 aattcctgcc ggaccttcgc atccaccgcg ccgaacggtt catccattaa gagaaccgag
   102121 gggcgaggtg ccagcgcccg ggcgatcgcg acgcgctgtc gttgcccgcc ggaaagctgg
   102181 tgcgggtagc ggctaccgag tccgtcgagg ctcatcaatg agaggagctc cagtacacgc
   102241 tgttcgatat cctgccggtt ccacttcttg atcttgaggc cgaaggcgat gttgtcgaag
   102301 accgtcaggt gcttgaagag ggcgtaatgt tggaacacga agccgatgtt gcgttcctgc
   102361 acggtgaggt cgttgacgcg cttcccatcg atgaagatgt cgccggaggt tgggacttcg
   102421 aggcctgcaa tcaaccgcag caccgtggtc ttgccgctgc cgctcgggcc gagcagtccc
   102481 agcagttcac cttcgtgcac cacgaacgaa acattgccga ccgccgttcc ggaaccgaat
   102541 tttttggtga gcccgcggac ttctattttc accggcttac tgcgctcctg cttctgcgac
   102601 ggtcgtttcc gctctggcct tggcgatctc cagcaccgtg aggatcgcga aggagacggc
   102661 gagcagggtc aaggccacgg cattggccgc cacgtaattg aaatcgacat aactttgata
   102721 gatatgcaag gtggcagtct gggtcagcaa caggatattg ccggatacga ccagcacggc
   102781 tccgaattcg ccgatggcgc gcgccacggt gagcgtggcg ccataaacca gaccccagcg
   102841 caaggcgggg agcgtcacct tgagaaagac ttgccactcg cccgccccca atgtccgtgc
   102901 ggcctcttct tcttccgtcc ccagcgtctg cagcagaggc gtgagttctc gcaccatgaa
   102961 gggaaaggtg acgaacaggg tggcgagaat catggcgggc agcgcgaaga gtatcttgat
   103021 atgcgcctgg ccgaacaacg cgcccagcat ggtgtccggt ccgaacagca ggatcagcat
   103081 gaatcccgcg atcacgggcg agacggcaaa aggcaaatcg atcacgccgc tgaccaggct
   103141 gcggccccag aactgttggc gcgccaacac gagcgccgtg agggttccga aaatcaggtt
   103201 gagcacgagg acgatcagcg tgatttccgc ggtgagggtg aagccatgca ccgcttccgg
   103261 ccgggagatc tccgtccaga acgccgccag cccctcgctg aaactttggc tcgccatgta
   103321 cagaatcggg ccgaccagga gcaccagaaa atagagccag acgattccga tcaacaacca
   103381 acgcatgccc gcactcccat tacacgtcac acaatctcaa acccggctgg cttttcagtg
   103441 cgccgccgtc gccgctgccg catcacggcc gggctgatcg tgccggttcg cccagcgaaa
   103501 cagtttgggc aaccgttcac cgggacgccg ggtcaaccgt tccaagagca gcagcaccac
   103561 aaacgaaatg agcagaatca gcaccgagac ggaggtcgcg gcctgggggt tgtagctttc
   103621 gatttctccg tagacgtaga ccgacgccac ctgagtcttc atcggaatat tgcccgccac
   103681 gatgacgatg gagccgaatt cgcccaaagc ccgtacgaag gtcagaaaca ctccggtcag
   103741 cagcccggga aggaccgacg ggaccgtcac cttccaaaag gtcgtccagg ggctcgctcc
   103801 gagggtgaat gccgcttctt cctgatcgcg ttccagtccc atcaacaccg gctgaaggga
   103861 gcgaatcgta aacggcatgg tgacaaacag catggccaga atgatgccgg gctggttata
   103921 cagcaccgtc aggccacctt gctggagcca ggtgccgagc acgctcgtgg gcccataaat
   103981 ggcggcaatc atcagcccgg cgacgagagt gggaatggcg aagggcagat cgaccaacgc
   104041 attcaagagc cagcggccgg gaaattcata acgcaccagc acgagtgccg aaagagtgcc
   104101 gaagacggca ttgatggcgg tggcgatcgc ggatgtttca atggtcagcc agagggcggc
   104161 tgccgcttga ggggccgata aatcctgaat gaaacggtcc catcccgagg cgatggattg
   104221 ctgcgtcagg gtagccagcg gaagaaagat cagcagcagg acatacccca ccgctgcaga
   104281 ccgtagtgcc acacgcaaga gcatgtgtga ggtcatgcgc ccgttccgtg tctgtggtga
   104341 cggtcattta tgtttggcat gcaactattt ccacttgtgg tggcgatcat gtgttactgg
   104401 ttcattcaca ggaggctcaa caggtcagtc cagcaaggcc gcagcgagtg aaggcctgag
   104461 ctgcatgttc ttacccgccc accctgagcc tggcgagaca gactcatgtc ccatgggcgg
   104521 tacgttgagg gcctgaacga tgcgagaacg ccgctggctg gcctgttcag cctcctgcta
   104581 tttctttgac acgtcttcga caatcttcgt ccacacgccc tgtgcgccga agagtttggt
   104641 gctcacggac tcccatccac caaggtctgc aatggtgaac agccgggccg gttgaggcag
   104701 ggcggcaccc gaagcaggcg ccactgcgcc acggtccaac ggacggaatc ccagttcgat
   104761 gaacgcagcc tgcgcctccg gaccatggag gaaagcgacg aacgcttcag ccagatcctt
   104821 ggccttgtgc cggtcggcat aggtatcgac caccgccgcc gggttttcga tccacaccgt
   104881 ttcggccggc acaatgagtt cgtaggggcg cccgcttttc acgcgcggca acaattcgtt
   104941 ttcataggtc acgatcacat cgccgacgcc gcgttcgaac gtcgtcaccg attcccggcc
   105001 gcttttgtcc atgaccttca cgttgcgctg aatgcgcgtg agcaagtcga ccgcctgcgt
   105061 cgccgccgct tccggagcca ccggttttcc cgcccgttgt tcggcgagtt tcagccctgc
   105121 gccataaatg gcgatcacat cccacatggc accgccggag gttttgggat tgggatacag
   105181 cacttcaacg ccgggccgtg ccgcatcttc ccagcccttc acgcctttgg gattgccttt
   105241 ccggacaccg agcgccacga ccgaggcgga gatcatgcct ccatgcggag ctttcctcca
   105301 gtcatgcgta atcaggccgg ctttggtgat ttgatcgaca tcgccttcca gcgagagcac
   105361 ggcgacatcc gcatcgaacc ctccgatgat ggcgcgcgcc tgggctccgg acgccccgta
   105421 cgaactgcgg acccgcacat cctgtcccgt cttctgtttc caataccgtt ggaaggcggg
   105481 aatgatgtgt cgttcatagg cttccttggg cacgctgtag gccgccagaa tcaaatcgcg
   105541 cgtctcggct gcgtggctcg gtgcaaccgg gaacgtgaac agaccccagg acgcgatgac
   105601 gctgagcatc agggtcgaaa atgtatgggt gatggtacgc atcaggatcc ttccgccagt
   105661 ttggtatggg caaatcgact caaggtgtaa tggtcgagaa tgttggcaat ggcatcgcgc
   105721 acctccccca tggcctgctg gagcggacag gagggtttag cggcgtaagg acagtcggag
   105781 catttttgat aggcggtttt gctcacacag ctaatcgggg ccagtggccc gtccagaatc
   105841 cggatgacct gcccgagcgt gatttcttca ggggatttga tcagtgaata cccgccgcga
   105901 atgccgcgcc gactcgccag cagcccggcg cgtttgaggg cgagcagaat ctgctcgaga
   105961 aattccacag ggatgttctg ccgctcggca atctcatggc gctggaggac gcgccctcca
   106021 tacgtctcgc agagctcgag aagcgcccgg agcccgtatt cactcttttt ggagaacttc
   106081 atggtcgagg tagttgtcta gtgagttgct caagatttgg cagaataaac cagcgcgtct
   106141 cgcgattcaa gcgattcgac cacgaggtgg cgaagaagaa atccgttcca ctgcgtagcc
   106201 ggttccatcc tgcaacctat tgaaaacgga cgctccgttt cttgacaccc tgtaaccgtt
   106261 cttgctagct tcagcgtgat ttttgtccgt caccacgagc agcctgcggc tagatctgga
   106321 catccggtga atttccaaga cctcattttg actctgcatc gcttctgggc cgaccgtggg
   106381 tgtgtcatcc atcaaccgta tgatctggaa gtgggcgcgg gaacatttca tcccgccacg
   106441 ttcctccgct ccctcgggcc tgaaccctgg tccgctgcgt atccgcaagc ctgccgccgg
   106501 ccgaccgatg gccgctacgg tgaaaatccc aaccgcatgc agcattacta ccagtaccag
   106561 gtagttttga aaccagctcc ggacaatatc cagggactct atctggagag cctcaagcaa
   106621 ctgggcatcg atcccaaaaa gcacgacatc cggtttgtgc aggatgattg ggaatcacca
   106681 acgctggggg cctgggggtt gggctgggaa gtgcgtctcg acggcatgga gattacccag
   106741 tttacgtatt ttcaagaaat cggcggcatt ccgctcaatc cgatcaccgg cgaaatcacg
   106801 tatggcaccg agcgcatcgc catgtatctg cagcaggtcg ataacgtcta cgatctgcag
   106861 tggagtgacg gcgtcaccta cggcgacgtg catcaccgca gcgaagtcga gttttcacgc
   106921 tacaacttcg aagagggcga ggtgcccatg ctgatggcca ccttccaatc cttcgaaggg
   106981 gaatgtcagc gtctgctgga caagaagttg acgttgccgg cctacgatta ctgcatcaag
   107041 acctcgcaca tgtttaacct gctggatgcg cgcggggcga tcagcgtcac tgagcggacg
   107101 tcctacatcg ccagggtgcg ggcgctggcg cgtcgctgcg cggaatcgta cgtggccgac
   107161 cgggaggcca tgggccatcc tttgatcaag caaccggctg gggcaggtaa gggaaccatc
   107221 aaccactcac cggtcactac caagtagccc gcggatccta tttccacaat gccatctaaa
   107281 aaaaccaaga cgaagaccgt ttcacgcgcg aagaagcctg catctgcctc acgcgccaag
   107341 actccctcta cgacggaatt gctgctcgaa atcgggacgg aagagttgcc ctatcagttt
   107401 gtcgctcccg cgttacgcgc cttgcagcag ggagcggaga cgttgctgaa agactcacgt
   107461 ctcacctacg gcactgtccg gacgatgggc acaccgcggc ggctcgtgtt gttggtcgaa
   107521 gggctggcgc gacagcaggc ctccgccgtc aaagaagcca tggggccttc aaaagccgtg
   107581 gccttcgatc agtcgggaca gccgacgaga gcggccattg ggtttgctgc gggtcaaggc
   107641 gtgccggttg agtctctgca agtccggcag acgcccaaag gcgactatct gtttgcggtg
   107701 aagccggaga agggccaggc cgtggctgcg gtcctgacgc aggcgttgcc gcagttgttg
   107761 gccaagttgt cgtttcccaa ggccatgcat tggaaccaga ccggggtgcg ctttgcccgg
   107821 ccggtgcgtt ggttgattgc gctctgcggg ggcaaggtcc tgccgattca gttcgcgacg
   107881 atcaaggccg gcaattacag ccaggggcat cgagtgctgg gtgcgaaggt gtccagcccc
   107941 aaaggtttcg ccgtgcaatc catcgcgcac tatttcaaag agaccgaacg ccacagcgtg
   108001 atcgtcgatc aggatcgccg gcgcgccatg atcctcgatc aactagccgc gttggccaaa
   108061 tcagcacgcg ggcacctgca tcaggacgag gagttgctgg agcaggctgt ctacatggtg
   108121 gaatgcccgc tgacgattct cggttccttc aaaccgcatt atctggcgct cccgaaagaa
   108181 atcctgatga cctcgatgaa ggagcatcag ggatattttt ccctcgtgga ctccaagggc
   108241 gcgctgttgc ccaatttcct cgcggtcaca aatatgaagt tggcgaacat gcagttgatc
   108301 cgtgagggga acgaacgggt tctggctgcg cgcttggccg acgcgaaatt tttcttcgac
   108361 gaggatcgca aaacgtcgct ggcggatcgt gtggcaaagc agctcgcggt caccttccac
   108421 cagaaacttg gcagcctcca tcagaaaacg cagcgcgtcg tggcgatggc ggctcatctc
   108481 gccgggcagc ttggtgacga ccaattggtt cacgactgcc ggcgcgcggc ggaactcagc
   108541 aaagctgatt tgttgacggg tatcgtcggc gagttcccga ctcttcaagg catgatgggc
   108601 ggggagtacg cgaaacacga cggggaatcg gcgacggtca gcgccgcgat tcgagaacag
   108661 tatctgccac gggcgatgga aggagagttg ccggaatcgc tggcagggaa agtgctctct
   108721 ctggccgacc ggttagacag cattgccgga tttttcctgg tcgggctggt tccgagcggc
   108781 tccgaagatc ccttcgccct cagacgccat gccacggcga ttgtgcgtat tctcatcgag
   108841 agccgattgc agatcaatct cgcgcaagca gtgcgggcga cccaggaagg gttggccggt
   108901 cagcatgtgg cggctgcgcc tcagccggcc aaaggcggcg cgccggacgt gatcggattt
   108961 ctttttgagc gggtccgttt ttacggaaaa agcgcgcacc aattgcggga cgatgtgatg
   109021 gaggctgttc tgaaatcggc cgaccgccag tccatcgatc tcaccgacct cttcgacaag
   109081 atgcagtcgc tgcagcagat tacgtcgagg gcggagttcg atccgctgat cgttggattc
   109141 aaacgcgcgc atcggctgac cgaaaaggaa cagtgggatc gtaagccggt ggagtccggg
   109201 ttatttcggg agcctgccga gtccgcctta tatgagactg tgcagcaaag ccatgctgcc
   109261 tatgcggccg ccatgcgcgg cgggcaatac ggacaggcgc tggacgtgct ggttcggatg
   109321 aagggtccga tcgacgactt tttcaatgcg gtgatggtca acgccgacga tccggccgtg
   109381 cgtggaaacc ggctgtcact cttgaaagag gtcgatgatt tgttcatgtc attcgctgat
   109441 ttctcccaga ttatggtaca agggacgtag cggatggtga gcatttggac tcaacttcag
   109501 agagccaccc tgagtcaccc gaggccagtg cctcggctca agtaagagcg accaaagtcc
   109561 ggcgatttgc gtccggcatc agcgtcgtga tgatggtggt gtgcaatgcg gtcttcctgt
   109621 tcggcatctg ggtgaccggc ctgaattttg aacggctggt gcggacaccg gatatctatg
   109681 attccagaca agacatttgc ttgcgactgg cctaccaaca tgttccgggc tcggaaaatc
   109741 ccgtgcagtt ctgttcggag tggctcaacc tcgccgatcc aaccggaaaa acccatacgt
   109801 ttcagaaaga cgcacaactc aagcagggtg cagacggatc attctatttc gactacggac
   109861 cgttcgtgga ctatcgtctg tttgcggtcg gcgcgttcgt cgtggggatc atcgtgtgtg
   109921 gcattcgcgt gaccaggcac gtcgtcaacc gctatcgtat gcgactggaa gccgccgccc
   109981 gccattcggt tccgactcat tgacctcata gcagaaggag agcgtcgcgt ggccaagaaa
   110041 tacgtctatt actttggaga tggaaaagcc gaaggcaccg gcaacatgaa ggaactgctc
   110101 ggcggcaaag gcgcaggtct ggccgagatg accaatctca aagtgtccgt gccccccggg
   110161 tttacgatct ccaccgaggc ctgcgtcgaa tattacaagc ggggcaaagc ctaccctccc
   110221 ggcatgatgg aggaagccct ggtggcgctc aagaagatcg agcggtcgat gaaggcgggc
   110281 ttcggcgatc ccgacagccc gttattggtc tccgttcgct ccggtgcgcg tgcttccatg
   110341 cccggcatga tggataccgt gctgaacgtg ggattgacca ccaagaccgt gcacggcttg
   110401 gcgctcaaga ccaagaacga acggtttgcg caggatagtt atcgccgctt catcggcatg
   110461 ttcggcagca tcgtcatggg catcaatcgc gagcatttcg aggacattct caaacataaa
   110521 aagcgcgatc tcggggtcac gcaggatacg catctcgatg cgaaggcgct caaggaactc
   110581 gtcgtcagtt tcaaggaact cgtcaaagag gaaaccaagc gcgattttcc ggatgatccg
   110641 ctcgaacaac tacgcatggc tatcaatgcg gtgttctcct cctggtacgg cgcccgggcc
   110701 gtgacctatc gtcgcctcta caatattccc gaaacctggg gcacggcggt gaacgtggtc
   110761 gccatggtgt tcggcaacat gggcgagacc agcgggaccg gcgtggcctt cacgcgcgat
   110821 ccggccaccg gtcagcggca attcttcggt gaatgcttga cgaatgcgca gggagaggat
   110881 gtcgtcgccg gcattcggac tccgttgccg gtcaatcagc tcgaaaagtt catgccgcag
   110941 gcctacaaag atttggaagt cacttataag aaactggaac ggcactaccg cgacatgctc
   111001 gacctggagt tcaccatcca ggaaggcaag ttgtacatgt tgcagacccg cgtcgggaaa
   111061 cggaccggcg tggccgcggt gcggattgcg gtcgatatgg tcaaggaagg actgatttcg
   111121 aagaaggaag ccttgcagcg gatcggcccg gaccagttgg cacagtatct ctatccgatt
   111181 ttcgatgcga aggaagaatc gcactgcacg ccgctcggca agggattgcc cgctggcccg
   111241 ggagccgccg ccggaaaaat cgctttgacg gcggatcggg cggtagagat gcaagccgca
   111301 ggtaaccgcg tcgtgttggt ccggcaggaa accagcccgg atgatatcca tggcatgaat
   111361 gccgccctgg gttttctcac cgcgcgcggc ggcatgacct cccatgcggc cgtcgtggcc
   111421 aggcagatgg gtaaggtttg tgtggcgggt tgtgaagcca tcgaggtggt ggacaatcaa
   111481 acggtacgga tcgggacgca gaccttccgt gagggcgact acctctccgt caacggctcg
   111541 accggcaatg tgtacggcgg ggatattccc gtggtggaat ccgaagtcat tcaggtcttg
   111601 caggggaaaa tggaggccac ggcttctgag aaatatcaat tgttcgaatc cgtgctgaag
   111661 tgggccgacg gggtgcgcaa gctcaaggtc cgggcgaatg ccgatgtgcc ggatcaggcc
   111721 cnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
   111781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ngacggggtg cgcaagctca
   111841 aggtccgggc gaatgccgat gtgccggatc aggcccgtat cgcgcggagt ttcggcgccg
   111901 aaggaatcgg tctctgccgc accgaacata tgttcttcgc cgaggaccgc atccagatca
   111961 tgcaaaaaat gattctcgcc cggaagcgcg aagagcggga aatgtatctg gatcagctgc
   112021 tgccgttgca gaagcaggac tttatcggtc tgtatcgtga gatgaagggg ttccccgtca
   112081 cgattcgatt gctcgatccg ccgctgcacg agtttctgcc gaagcgtgag gacctcatgg
   112141 tcgaaatcgc tcagctcgaa ctcaccagtg ggtcgcagac ggtgctggag gagaagaagc
   112201 ggttgttgac tcgcgtcgaa gaactgcatg aattcaatcc gatgctcggc ctgcgtggct
   112261 gccgtctcgg tattacgatg ccggaaatta ccaagatgca ggcgcgcgcc atcatcgaag
   112321 cggcgtgtga actggcgaaa gaaggcacca agatcgtccc ggagatcatg atcccgctgg
   112381 tcggcatggt ctcggaaatg aaggcccaga aggaccttgt ccgggaagtt gcggccgaga
   112441 cgatgaagcg gtatggcgtc aagttgtcgt acttggtcgg cactatgatc gagttgcccc
   112501 gcgcggccgt gacggccgat ggtatcgcgg aagaagccga gtttttctcg ttcggcacga
   112561 acgatctgac tcagaccact ttcggcttct cgcgcgatga tgcggcaaag ttcatcgatt
   112621 tctacaaaac cgccaatatt ctggagagcg acccatttgc ggtgttggac cgtgaaggtg
   112681 tcggttccct catgcgcacg gcgatcaccg gtggacgtaa aacccgtcca accatcaagt
   112741 tgggcatctg cggcgaacat gggggcgatc ccagttccgt ggagttctgt caccaattgg
   112801 gattggacta tgtgagctgt tctccgtatc gagtgggaat tgcgcgattg gctgcggcgc
   112861 aagcagcgtt ggcggaagcc gagaaagaga agcccaagcc ggcgaagagc aagccgaagg
   112921 ccgcgaagcc gagcgccgtc aagtctgtca agaagtcggc gaaatctgct ccggcgaaaa
   112981 aacggccggt tgcgaaacgc gtggtgcgcc gctccaagcg tacgagccgg tgaaattatc
   113041 ctcccgcgat cgtgaagtga tggccctggc ccttcgcctc gctgcgaagg gccggggtca
   113101 taccagtccc aatcccatgg tcggcgcggt ggtcgtgaac cgcggagaga ttgtcggaca
   113161 gggctctcac cgcaaggccg gtggtccgca tgccgaagtg ctcgccttaa gtcaggccgg
   113221 ttcacgcgcc aaaggcggca ctctctacgt caccctcgaa ccctgcagtc atctcaaaaa
   113281 acggacgccc ccttgtgtac cgctggtcat ttcctccggc gttcggcgcg tcgtcgttgc
   113341 catggtggac ccgaatccac aggtgcaggg gagaggaatc gcccagctca agcgggcagg
   113401 cattcaggtc gaagtcggat gcctcgaacc tgaggcgcga cagctcaacg aaacgtatat
   113461 ccattgggtg cagaccggcc ggccattcac cattctgaaa gccggcatga cgttggatgg
   113521 tcagatcgcc accgccaccg gcgaatnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
   113581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
   113641 nnnnnnattc tgaaagccgg catgacgttg gatggtcaga tcgccaccgc caccggcgaa
   113701 tctcaatgga ttaccgatga ggcggcccgg atgcaggccc atcagttgcg cgccgacgtc
   113761 gatgccgtgc ttgtcgggat cggtacggtt ctgcgcgaca atccacagtt gaccgccagg
   113821 acgggtggtg atcccgtccg ccttgccgcc aggcaaccgc tccgtgtggt ggtcgacagc
   113881 cgactacgta tcccgtcccg ggccgccgtg ctgaaacggc aggaagaagc ccacaccgtg
   113941 attgccacca cgcgcgcggc ctcagtaaca aaggtcgagc gcttgcgagg ccagggcatc
   114001 gatgtcctgg tgttgcccgc tgccggcgga cacgtcaatc tcacggcatt atgggcgagg
   114061 ctcggacagc tcggcgtcac gagtgttctc gtcgaaggcg gcagcgatct caatgcggcc
   114121 gtgctgcgag cgggactgcc ccagcgcttg atgtgttttg tcgccccgct gctgctgggc
   114181 gggcaggatg cgaaaggggt gttgggaggg ctgtcaccgc gccgcctgcg ggaagccgtg
   114241 ctcctcaaca atctacgcat gacgcctgtc gggcgtgata tgctgatcca ggctgacttc
   114301 ccgactcgat aggagtattg tgcgatcttc tctccgccct gcgtacaggg ttcatccgcg
   114361 gcgccccggt ctgctcctgt ccctcgtttg catctggttg gcgctgttgt cggtttcttt
   114421 gactcatgca gccgaaacag catcctcgtc ggatcttgcg gcgcaggtct ggcaatacct
   114481 cacgactcag gacagcgagc aggccaattc ggcgctggcg tccatcatgc agcggcctga
   114541 tgcaacgctt caggccgtgc aggacatcct gcgcaagggc cagccccatg gccttcagcc
   114601 tgtcggggtg ttggcggatg aacaggtcat ggttcgcgac cggccctatc gggtgagtct
   114661 gtccattccc cagagttacg agccgactaa agactatgcg ctggtggtat gtctccatgg
   114721 cgcggggttc accggtgaag cctatttgga ccgatggaag tcgcgcttag gcgaacaata
   114781 tatcctggcc tgtccaacct atcccgcggg tgcctggttt accagacggg ccgaagatct
   114841 cgtgctggcg acggtgcacc tcgtccggga gcggtatcga atcgatccga atcggatttt
   114901 tctcagcggg atgtccaacg gcggtatcgg cgcgtggctg atcggtatgc atcatgcgcc
   114961 cctgtttgca gggcttgccc cgatggccag tggcatcgac gatgtcttat ttccgttcct
   115021 ggaaaatctc cgcaccacgc cggtctacat cattcatggc tctcaagacc aggtgatgcc
   115081 cgtggaactg agtcgcaagc tggcgggtga gctgaagaac ctcgattacc cctacatcta
   115141 tcgtgaacat gaccggaccc atgccatggc cggcggccat ttcttcccgc gtgaagagct
   115201 gcctgatctg gtgaagtggt tcgataccca gcaccgcacg ccggttccca agaccgtgac
   115261 cgtggtgcgg gatgcgagtc atctcctgcc gttcgggtgg gtgcggatcg atgcaacgga
   115321 tcagatcgca tctttttcgg aagatctggt cgacaagcga gacgacagca ttcggaagcg
   115381 gatctacgcc cgattgaccg cacaggtgac cggtccgaat cggatcgacg tgcggaccga
   115441 tcgcgtgcgg cagtacacgt tgtatttgaa tgaggacctg gtcgatttgt ccaaaccggt
   115501 cgtcattacc acagacgggc aaccgtcatt cgaaggcctt ctcgaaccac atgtcgagac
   115561 gctgttacgg caggctcgcc tccggcagga tcctgcgcag ctttttcccg ctcacgtgac
   115621 tgtgaccgtg cctcaacggg cttcatgacc gggggcggcg agatggttcg gcgaatcggc
   115681 ccgttggccg ctgtgctcac cgccgccttg gctctctgcg attccaccgg gcaggccgaa
   115741 ccagaacgct gttccctgcc gtcgcaccat gtcggcatgg tgttccctct cgatcaggta
   115801 gatgctgcct ggacctgccg gcttgaaccg atcattgcgc attacaccac ggccaataag
   115861 gtgggaccga tccgtacctt gctgccggag gatgtctatc tctatctgtt ggagcatccg
   115921 gtcatggccg cggccctcgt gaatcgtctc gatctcgggt tgtacaaagc tgagtggcgc
   115981 ggtcccgatg aattctgggc gacggacggt gaaggcacgg aaggcatcgt gcatcnnnnn
   116041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
   116101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnctcaa agccgccctc gcgtccctcc
   116161 acaatcctgg gcagaagccg agccccgccc ttccatgaga aagtgatgac gacgtcccgc
   116221 agctttttct acctctgtac cctcggcgta ttttgtttca ttagctataa cctcgttcgc
   116281 atgccggtcc tgtccctctt cgcggaatcg ctgggtgccg ggccggagcg gattggattg
   116341 atcgtctcgg tatcgacgat taccggggtg ctgctgaaat tgccgtcggg tgccctgtcc
   116401 gatatttatg gacggaagat gctgctccgc atcggggtgg tggcgttcgg gttgccgccc
   116461 tttatctatc cgttcatttc cgatctcaac gcgctgacag cgttgcgatt tgtccacggc
   116521 ctggcgacgg ccatcttcgc gcccagcgcc ctggccacgg tagctgatct ctacaaggag
   116581 cggcgaggtg cggcgatggg aacctatacg gcctgtaccc agtccggttc cctccttggc
   116641 ccttttattg gaggatggtt ggcccatgcg gcggggtttc cagcggcatt tgtgacggcc
   116701 ggtgtcttcg ggtgcatcgc cattctcatc ttcttcagcc tccatttgga cgagccgcct
   116761 ccgcgtgtac gcgagaaggg gctggctccg gtgatcaccg agatgggaaa agggtttctc
   116821 gcagtggccc ggaaccggaa agtgttgatt accagttcca ccgatgccgc caagatgatc
   116881 gccaatggcg cgctcatggc gtttctgccc ctctacggcc tgtcagtcgg cctgaacgcc
   116941 ggtgaagtcg gcctgatgtt cagtgtgcag gcggtgacgt cctttttgtc caagccggtt
   117001 atggggcgca tatcggatcg ggttggtcgg cagccgttga tcgtgctcgg cctggtcatt
   117061 tgcgcggcga cgttcatcag cattccccac gtcggatcat tcgctgtgct gctgatgctg
   117121 tcctccgggt tcgggttcgg cgaagcggtg gtgtcatcct catcggccgc cctggtggcc
   117181 gacagttcgg aattcaaacg gttgggggcg ggaatgggaa tgcagggaac ggtcatggat
   117241 atcgggcatg ccagtggccc gctcctggcc gggtttttga tcgcccacgc cagctatcag
   117301 ggagcctttg ccgtgatcgc cggcatccaa attcttgcgg ccgtcgcctt ctgggcgacg
   117361 atgagaacca ttttgcggta gtgtataatg ccgccgcatt tgtcagggca gcactagaca
   117421 atcttttttt cacaaggacg cagcaaagga tggatacgga ttttatcgaa acgcttcaac
   117481 gcgggattgc catcgtgggc ggggttggat tgctcggatt ttgtctctat ctcttgaaga
   117541 cgcacaaggg ggcgtaagcc atgttcagcg gcattgtgga ggagatgggc gcggtttcca
   117601 tcctgaataa ggggttggcc ggcacccggc tcaccatcat ggcctcgact atcatgaccg
   117661 atctgacgat tggcgccagc gtgagtgtga acggcgcatg cctgacagcc gtcgccagaa
   117721 ccgatcatga tttctcggtg gacgtgtcgc ccgaaaccct ctcggtcacc accctcagtg
   117781 atctcaccac cggatcgcct gtcaatttag agcgcgccat gaaactgaac gaacgaatcg
   117841 gtgggcacat ggtctccggc cacgtagacg gcatcggcgc gattcgcagc cggcatcagg
   117901 atggcaatgc gctggtcctg gagatagaag cgcccaaaga catcttgcgt ctctgcgttc
   117961 acaaaggttc gatcacggtg gagggtatca gcctgaccat caacgaggtg acggagcgct
   118021 cattcctcgt ggcgatcatt cctcacacgg ccaaagtgac gacgctcggt ctgaaacagg
   118081 taggcgacaa ggtcaatctt gagtccgacc tgatcggtaa gtacgtcgaa cggcttctgc
   118141 aggatcgagg gcttcttccg ccgaaaccca cccccgtcat cgacaaggac tatttgcagc
   118201 gccgcggcct gatttaacag gatgctgaaa aagttcgcca gcggcgttct cgcttcgttc
   118261 agatcctcga cgtacccggg aaggcctcgg gcctaagact cttcccggct catcgttccc
   118321 tagtacccac acatgttgag cttcaggctt ctcgcgccgt gggcttcggt actggtctgc
   118381 ctggacggcc ttttgatcat cccgtgttgc cggaattggc taggacagat cagctacttc
   118441 agcagaaacc ctttggagtc ttcgccggac gctgtggtga cggtcatgat ggccatgcct
   118501 ttgcgcttgc tcgcggggac ggtggcggtg atttgagtcg gactgtcgag cttgaaggtc
   118561 gcggcatttc caggcccgaa ggacagggat cgcagacatt ctgccgggcc gaaattcatc
   118621 ccggagatgg tgaccttctc cccggctttt ccttcatcgg gtttgacgga ttcgattttg
   118681 ggcgcttccc cgaaacaggc ttgagctttg gctgccgttt ctgccgaggc atacttggtc
   118741 gccggggatt tgactggggc ggtggtggtc ttccggccct ctcccttttt caccgacttc
   118801 ttctccggag cttttttcgc ctgagcggga gcctggcccg cggctttggg tgtatcgtcc
   118861 gcagcgagaa tgggaaccac tcccccgagt aagatgatgc ctgtgaccat tgaccacagg
   118921 agtccacgtg ttgtccgttg ccctagcatg accggcctcc atgctttcgt tagagatgat
   118981 gctgaccccc agtggatcag cttagtcttc aatcgtggaa atatccccca cgtcctgtcc
   119041 caactccttg gctttgagca ctcgccgcat gattttgccg gagcgcgttt tgggcaagga
   119101 tgacacaata tcgatttcct gcggcacggc gatttttccc agttccttca gcacatggtc
   119161 cttgagggac tgcaccaact ccttcgaatc ctggtagccc tgcttcagaa tgacgaaggc
   119221 tttgatcgct tctccggcgg tccggtgcgg cttgccgatg acggccgctt cagccacggc
   119281 ttcgtgactc accaaggcgc tttcgacttc cgccgtcccg atgcggttgc ccgccacttt
   119341 gatgacgtcg tcggcgcggc ccatgaacca catgtagccg tcctggtctt tccggcagac
   119401 gtcgcccgcc gtataacaat tggggatggt gttccagtag accttgtagc gatccgggtc
   119461 tttataaatt gtacgcatca tcgcgggcca gggcttcttg atcaccgcaa agccgccggc
   119521 attggcgggc aggctgttcc cttccttgtc caccacgtcg gcttcaatcc cgaggaacgg
   119581 gcgcgtcgcc gaaccgggct tgagtgggac agacgggagg ggcgtgacca ggatcgcgcc
   119641 ggtttccgtt tgccaccagg tgtccatgat gggtttgtcg ctgccggtca cgcgatagaa
   119701 ccattcccag gcttcgggat tgataggttc accgacgctg ccgaggatgc gcaacgtgga
   119761 caggtcgtac ttcttcggcc actcttcgcc atatttcatc aacagccgga cggcggtggg
   119821 cgtcgtataa aaaatggaga cgccatagcg cgaaatgagg tcccaccagc ggccggggtt
   119881 ggggtaatcg ggtttgccct cggccatgag gatcgtggcg ccgttcaata gcgggccata
   119941 gacgatgtag ctgtgcccgg tcacccagcc cgggtcggcc acgcagaaat acacgtcctc
   120001 ttctttcaga tcgaacacgt atttcgtcgt gatgtatgtg ccgaccatgt agccgccatg
   120061 gacgtgcacc acacctttgg gcttgccggt ggtcccggac gtgtagagga tgtaaagcgg
   120121 cgtttcggca tcaagtggtt ctgcggcaca gacggcgttc tgctctttca gccaatcggc
   120181 ccaatcgatt tcttttggcg cggtgagtgc aacgctgagg gcatcccggc gcaccacgac
   120241 gactttttcg acggaggggc aggattgcac ggccgcgtcg accacgggtt tgagcggaat
   120301 ggtttttccg cggtcgtacc cgacgtcggc ggtgatgacg agacgcgctt ccgcatcctg
   120361 aatgcggctt gccaaggccg gcgcactgaa tccggaatac acgacgctat gaatgatgcc
   120421 gaggcgggcg caggccagca tggccacgac ctgctcggga attttcggta aatagatcgt
   120481 gacgcgatcg cccttgttca agccaagggc tttcagggca ttggcgcagc ggttgacctg
   120541 gcgcagcagc tccccatagg tgaagatgcg ttcttcacca ttctcgccga cccagatgat
   120601 agcgacctta ttgcgacgcc agccgttcgt atggcgatcg aggcagttgt aggcaatatt
   120661 acaggtcgcg ccgacgaacc atttcgccca ggggtagttc cactcgagca cccggctcca
   120721 cggggagaac cattccagct ccttggccac gccgccccag aaggcttcgg gatcggcaat
   120781 ggaagccttg tacgcctggt cgtaatccgg gatgtgcgcc gccgctttta tccgggcgga
   120841 cggctgaatg acacgtccct ctttcaatag cgtatcgatt ttctcactca tgagtcgcca
   120901 tacctccaca aaacgcgggc ctgtccgatg cgcggttcaa tctctccggc attatgcgga
   120961 tggggcggag gaactgcaac cctcaagccg cagagaggtg ccgctggagc gcagcgaatg
   121021 accgcgtggg acaagcgttg gcgccgatgg cctttcttga cagtcgggac gacgcgaggg
   121081 taggctgagt ccgttaccct tcactggatc atcctgctga tgcgttcgcc gagatctctc
   121141 acgttccccc ggatgatcac ctgcctggcg gccttattcg tcgccggaat gtccactgat
   121201 catgcggctg cccaggtcgg gaagccggag ggactctatt acaaatcatg ggccgtcgtc
   121261 gtcggcattg agaattatct cgtcgcgccc aaggtgccgg gagcgctgga gagctcacat
   121321 gcagtcgctg aagcgttgcg agggctcggg tttgatgagg tcatcgaaat ccaggacaag
   121381 gaggcggcct ccaaacggct gctccatatc ctcaacgatt acctgccgcg caaagtgggt
   121441 cggcaggatc gcatcgtctt ctttttcacc ggccatgccg gcctgacgca ggattctcaa
   121501 gccaaggatt cgggcttcgt ggttccatgg gacgcgcagc tcaacaatcc cgccaaagcc
   121561 attaccctgg atcaactcaa agagttcagc cggcgatcgg cgtccaagca catcctcatg
   121621 gtgttcgatg ccaacctgcg cggctgggac gtgaccgcgc cgcagccgct ctcgctggaa
   121681 gggcgattgt cgccggaaga tgacaccgag aaacgatcgg tgcaagtact cacggcagcc
   121741 gagaaagaag aatcagttgt tcgtacgtcg gggcagagcg cattcgtgac ggcgctagtg
   121801 gccgggctga agggtgcggc ggacctgaat aaaaacggct ggatcatggc cagtgaactc
   121861 gcggctcagg tgaagcagga cgtggagcgt gagaccaagg gggcccaaca tccgcaactc
   121921 cttcaacttg agggagacgg tgatgtcatt ctggtcgaag ggcggaaggc catgttttcc
   121981 gtcggcaagg aacccagtac cgaagcagac cggatgaagg aagcccgagt tcaatatgaa
   122041 caggcatttg ctttattgca gcagcagaag tcggcagaag aagcgttgga acgcctcaat
   122101 cgcgcgatca cgtacgatcc gtccttcggc gacgcgtatg tgttgaagag ttttatccgc
   122161 cttgaggtcc tgcccaacct cgaagaatcg ctggcagctg cacaggccgc ggtccagcat
   122221 gcgccgcaga atccggattc tcactactca ttggcgctgg ccctcgaaaa gaaaggccag
   122281 caccaggaag ctgagcgggc gatgttgcag gcattggccg tcaatcccgc ctataccgat
   122341 gtctattttt cactgggcac cttgtacgcc gaccacctga atgaacccca gaagtcggtc
   122401 gatgcctttc gccgatattt ggaattaggc ggccagagcg agcgcgccac cctcgccatt
   122461 caaggtgatc gtgctcccgg tgagaaaccc gctccgtagc accagtcctg accggcctac
   122521 catatcgtca gacttgatta aacgtgttgc gccgtgacgg gtcctacacc tattcattct
   122581 cactcaacga ctagtccttg cctccgccct tcagataccc cagtccgatc ttcaatgccc
   122641 ggcgggtgat ctcgggccag cgtacttggg gatattccgc cagcactgcg gctgccttcg
   122701 gatcctgaat atcgagttga acgacccgaa tgatgccgtc ttcaatctga acgtcagcca
   122761 tctgtttcat ctccttcgcg tatgctacgt aaaaatattt cctgtcgcag gtccagacgt
   122821 caaccgcaaa accggttgcg cgttgacagt cttgggggtg catgttagca taaaaactcg
   122881 ctttttcgcg ccattgtctc tcgtcaccca gtgaaccaca cacgtcgatc ttccatcatc
   122941 ttgccgcata caaccgagcc atcggatctc acaggtgcca caccaaggag gaatcgtatg
   123001 agcagagtag agggggcttt ctcgaagttc accggaagcg cgttgatgct ggtactcctc
   123061 atcgggctga cggcctgcgg tggtcccccg aactgggtca aaaagggatc cggcgccttc
   123121 aatgaaaaaa gcgataaatc cttctatggc gtcggctccg tggtgggtgt gcggaacgaa
   123181 ccgttagcct gggacacggc ggagaaccgc agccgggcgg aaatcgccaa gacctttgaa
   123241 acctataccg cgtatctgat gcgtgattat gctgcctcca cgacggcggg cgatttttct
   123301 cgcaacagtg aagagcagaa catcgagcgg gcagtgaaga ccttttccgc ggtcacgctg
   123361 aacggcgtca agcccatgga ccgatataag gacgaaaagt ccggcacgta ttacgtcctg
   123421 accaagctca gcctcgaaga catgaagaat aatctggagc aggccaaaga actcaatagc
   123481 caggtccgtg acttcgtgcg taagaatgcc gaccggttat tcgatcgtct ggaaaaagaa
   123541 gaagacaagc gggcgacgaa atagtcgaga cgttatccgg gtccgtggcc gggaggagtc
   123601 agcatgatcg agtggcgaga gcattcagtg ttgcgaacct gtgcggtggg gctattggta
   123661 ggatgcgcgg ccgtagtcag cgggtgcggc catgagacga aggtgacgcg ggtcgatacg
   123721 ggcacggtca ctgaccttag cgggcgttgg aacgatacag actcccagat ggtggctgag
   123781 gccatggtga aggaagccct cgccaatccc tggctgggca actttaccaa gggcaagaat
   123841 cgtcagccgg ttgtaatcgt ggggacggtg ctcaataaga gccatgagca tatcaacgtg
   123901 cagacgtttg tgaatgacct ggaacgtgag ttgaccaact cgcaaaaagt cacgtttgtg
   123961 gctgccaagg gcgaacgtga tgaggtgcgg gaagaacgcc gcgaacaggc tgtgcatgcc
   124021 cgcgaagata cgcaaaaagc gccgggcaaa gaaatcggcg cagattatat gatgcgggga
   124081 agtatcgcca cgattcttga cgaacaggac ggagcgaaag cggtcttcta tcagatcgat
   124141 ctcgagatgg tcgacctgga gaacaacgtc aagtcctggt tcggccagaa aaagatcaaa
   124201 aaagtcatcg aaaagaaacg cacgattttt tagccagacg tattcagttg agacctcacc
   124261 tcccatcgac cacggcctcc ccccagggag gccgtttcat ttcttggccc ttgcactctg
   124321 tcatcgggtg gtgcctgctg tgggtgctgt ccggctgcgg cctgtcatcc aaccattatc
   124381 tcctcatcga tcaaagcctg gcggcacacg acgctcgacg ggcggatgcg atcatggcgg
   124441 aggcggagtc ggaatatgga ccccgcaatc gtctcctcta cagtatggac cgggggatga
   124501 cccttcacct cgccggcgag tacatgcaga gcaatgccca gcttgaatcg gcggcacagg
   124561 aagtcgaacg gctgtatacg aggacgatca ggaccgaaac cgcagccttc ctgaccaacg
   124621 ataacgtgct gccctatgaa ggggatccct acgaacatgt gatgatcaac atcatcaagg
   124681 cgctgaatta cgctgcgatg gggcaactga tggaagccgt cgtcgaggcc aggcagatcg
   124741 atcatcgcct gaacgtcttg tccgatgccg ccaaggaaaa agacgggtac cgtgaagatg
   124801 cctttgcccg ttatctgacg ggcgtgttgt acgaggcgac cggcgatctg aataacgcgt
   124861 tcatcgccta ccggaaggcc tacgacatct acgatgcgac gaagagctgg gcgcggacgc
   124921 ccatgccgcc gatgctccgc gcagatttac tgaggacaac cgatgcgttg catatgacga
   124981 ccgagttcga agaataccgg cgcctgtttc ccgagacgcg ttggctgcct cgcgctgacc
   125041 aacagaatct cgcccaggtt gttgtgatcg gctataatgg ccgcgcgccg cgcaaggaag
   125101 acgcgtttct cgacatccct atcagtctga gcgcgctgca gttggtcttg ttgaatcgcg
   125161 gtgtcatcca tgcgtcgaat cgtcaggagc gccgcgtggc ggacagcgtg ttgtatggct
   125221 tgaatgggcg agtcgtacgg gtggctctgc ccaaactgat cctgcagaaa acgcaggtgg
   125281 tgcacgagac ggtgacgttg atccctcgag gaggagagcc gatttctgcg acatccgagt
   125341 tagtctacaa cggcaccgcc ctggctgagc ggtccctctc cgaccgctta cctggaatta
   125401 cgacgaaagc cctcgcccgg gcagctgtga aatttgccgc ggctgaagcc gcaacccgag
   125461 gatcgcagca tgcggtgaat aaaggcgacg cgccgtgggt cggattactg gtgggcgtcc
   125521 tcgcgcatgg attggccgtg gcgtcagaat ccgccgacac cagaagttgg cgcaccttgc
   125581 cggatgagat tcaaatttcc cgcctgtggg tgccgcccgg cgaatatgag agccggattc
   125641 aagccatggt tcgaggcaac ggaacgccgc aggtagaagg gccgcgccct ctcgttcttc
   125701 gagcgggaca aacgctgttt ctgatcgaac gagtgatgct gtgagggacg ctgaagccat
   125761 ggtctcggat cgaggcacgc gaatcagcct agtcgctctg gtcatgctgc tgtgcgccgg
   125821 gtgcggctgg gtcggtgggc catcccgtcc atcctggata gacggcagca gtacgcagtt
   125881 tccttccacg caatatctcg taggcgtcgg ccaggccgat tcgcgcccac aggcgacgga
   125941 acaggcctat gcggcggtgt cgcgcatctt taaggcggag attacggcgc aggccaagga
   126001 ttgggaatcg tacctggtgg tcgaatcccg cggacagaca agcactcagc gcaagttgat
   126061 tctggacaat gtcacgcgag tgaccacgga taaggtgttg gaaaacgtcc aagtcctcga
   126121 tacctggttt gaccaaaagg cgcgacagta ctatgctctg gcaggcatga accgggcgca
   126181 agccgaatcg gcgatgctgg aacgtctggc cgacctcgat cggtcgattc agacggaagt
   126241 cacggaagcg catcaggccc aggacaagct ctcacacgtg cgcaatctga agcgagctgc
   126301 caaaaatctc gtccttcgcg aagcctacaa caccgacctg cgcacaatcc ggtcgaacgg
   126361 gcaggggcat cccgccgcct atcgtgtggc cgaattgact gctgaattgg agcattatct
   126421 cgcggcgaat atggggatgg ccgtggaggt gtcaggtgag caggcggaac cgctcgagcg
   126481 ggcgctcatc gagggcctga cgcaggaagg gttctcggtc gtcggctctg gcccaggagc
   126541 ggctacggcg gaattgctga tcaccggaac cgtgcggatg tggccgatcc aagtccctga
   126601 tccccagttc cgctacgtgc gatggtgtac tgatgccgta attgaagaag tctcgaccca
   126661 tcgtgtcatc ggtgcggtat caaaaggcgg aaaagaaggg catgtgacgg aacgcgaggc
   126721 agcggctaaa gcggttcgcg tcatgcagca ggagttttca gcagacctgg cccaagcggt
   126781 ggccgcgcat atctacggag agagggactt atcggtgtca tcctctgcgc cgtcaggttg
   126841 tccgaaagag gcggggcagc cgccgctcag tcgttaacgg ccgcgaattc accatagaga
   126901 gaggagaggg aatggcaaag acagggaccc ggaaggcggg cgaacaggcc ggcggcggac
   126961 gccggatgtc cagtcaggca atgaaaaaac atctgcggga acggctcacc gccgatacgc
   127021 agcaggtgct gaagagcgat attgtgagca tctttcgcaa gcaaggctac tatgaggaat
   127081 tgccgttgga tgagctgcag gatcgcctct ccaagctcca gtcgccgttg gccgacagtc
   127141 tcttgaaggg gagggtgtag gatgccgtat tactattttg attccacggc gctggtcaag
   127201 cgctacagca tggagcgggg gacgcgtatc gtcaacaagc tcatggtgaa gcgggggaag
   127261 gtcgccatcc ttcccatgtg gagcgtcacg gatttttatt cggccttgtc cgtccgctcg
   127321 caacagggag agatcacgcg ggacgattgt tattcggtct tatacaagtt tgagatggaa
   127381 gcctcgcaag gactcttcca gttcatttcg ccgacgatgg acacctatct ggctgcgaag
   127441 gaattgattt tggactatcc ggcccttcgc tcgccgcagc ttctgcacct ggccttagcc
   127501 ctggagttga agccgctccg gctgaccgtc gtcagcgcag acaaacaact gctggccgcc
   127561 tgtcgtcctg ccgggttgca catcatnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
   127621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
   127681 nnnnnntcag cgcagacaaa caactgctgg ccgcctgtcg tcctgccggg ttgcacatca
   127741 tcaatccgga agacgactag cagagcagga tgcgaaacag cccgccggcg gcacggtcgg
   127801 attttcgtga attgatgttg agagcaggcc gttcaaaaag gtcgttcagc gaggccgcag
   127861 caatgcgagg aggcgaggcg tacccttgcg gtacgttgag cctcagagcg atgcgagaac
   127921 gaagctggcg gtctttttca acggcctgct agttggggca gcgaaattcg cccatcatcg
   127981 atgccagcac gatggcccaa tcgtctgctg tttgacggat ggcgggcagt tttggtgaga
   128041 ccgcaccagg tcggtctgga gtctccgatg aggcgagggt ctcctgggca tgttgtagct
   128101 caagctgtgc cagttggagg ctgccgcata cgccggcaga ggcgggaagt tctccaccgg
   128161 cccgccggaa gagagccagc ccccggtatc catgctcctg tgatcgatac aggtgttctg
   128221 tggatttgaa tacttgccgc aacgccggtt cagtctgacg tttcccgagt tgtgccgcca
   128281 ttagtgcggc gcggcccatg ttcatggccg ccccttccgc atcatcattc cccatcgcgt
   128341 cttctgcttt ggctcgtagc cggtcgagct ccgcctcttc gcccatcact tgagcctgtc
   128401 cgattccggc ggcggccacc agtatgaaga agctaaggat tgatgcggcg aggcaatgct
   128461 cgcaccggcc gatgtgtatg ccattcctca ctgtacgtgt tcccaggtat cgatttgctt
   128521 gatactccaa ttgaccgctt ccttcaattt cacgagattc gggtcggcat cattttcatg
   128581 gacgtggtac agcgatttct gaagggcgaa gagcggttcg taggcccgca tatccggcaa
   128641 ttttccgagc gcccaggcga cctcggtttt cacggcgaca tcttcggtgt tcagggtttc
   128701 aagcagaggg tcgacgatgg tgaagtctcc atgcagcgca ccgacaattc ccaacgcctt
   128761 tgccgcgggg gctcgtaaat cgggcgcacc gtttttcatc gtcttgatga ggacggggat
   128821 cgtatctttc tggccgatat tgcccagggc cagtgcggag gctttcgcga tgctccgatc
   128881 cggcccgttg aggccatcca gcaagcgcgg aatggctttc acggagaaga ggtcgccgaa
   128941 cagcgccact aacttcacct tgcgtgccac tggcgttttc ggatcgtcgt acagacgaaa
   129001 cagccgtgct tcctgtcccc attcagcggt gatgagggca ggaaaatcgt actcttcgag
   129061 gcgggcttgt aacctgccca tggcaaagga cgtgggatcg ccggccttcg ccagtgttgc
   129121 cgcagcctgc gcatcatcga agtctgtgcg gacctccttg cgccaggcca ttttcttacc
   129181 attaagcaga tagccgagct gacaggccgg tcccttccag atacgggatg gcgcatcagg
   129241 gagatcggcg tcgcttccca tcgtggtcgt gccctcccag gtctttttct gttcacattt
   129301 gatcttcaac tcgacatcgt gcggctgggt cgggtcggtc accggcgtat agccgaattc
   129361 cttcatgcga ttggccgcaa cctcggcgag cgggccggca tcgacagagc ccttgtcgga
   129421 aagagcgagg accgtgatca acacacggtc gattcgttcc atctggcttt tttgctcggc
   129481 ggtcagggcc tcccggcggg cccagctcgg gtcgccgtac agcaggagga ctcccagaat
   129541 gacaagcgag aggatgcatc tcatgtcggc tccattctgc tcaaaaagac gatgatggct
   129601 gtcctgtcaa tcactctata acaacccctt ccggcggttg caagttgcgc cggcttgaac
   129661 agcctccgta taatcgcgcc atgttgactg gacggcagat cggctttgtc ggcggcggca
   129721 acatggccga gtcgttgctg gcgggcctgt tgcggaaagg cctgtcctcg cctggccgtc
   129781 tggtcgtcag cgacccgctt gcttccagac gcgaactgtt gagccgtaac ctgggcgtta
   129841 gtgtcacgcc tgacaatcag gcggcggtcc gaggcgcgga cattgtggtg ctctgcgtgg
   129901 aaccgcaggt gctcgatgat gtgctgagag aactcgcgcc ctcgcttccg tcagacccag
   129961 tcatcatctc cgttgctgca gggtatccct tgtctcgcgt gcaacaccat cttccttccg
   130021 ccaccaggct catccgcgcc atgccgaata ctccatccgc gatcggcgag ggtgtaacgg
   130081 cgatgagtct tgcgccgggg gtgtcgtccg aggatcgtga gacggcccgc cagttgtttg
   130141 aatcggttgg tatggctgtc gtcgtagagg aacggctgtt agacgctgtg acggccttga
   130201 gcggcagcgg accagcctac gtgttcgcca tgattgaagc gcttgctgac ggcggggtgt
   130261 tggggggtct gccgcgatcc accgcacaac tgttggcagc gcacaccgtg gccggcgcgg
   130321 ccagcatggt gctggagcag ggcgagcatc ctgctgtact gaaagaccgg gtggcttcgc
   130381 ctggcgggac cacgattgcc ggactgtatc agttggaaca gagaaagctg cgggccaccc
   130441 tgatgtcggc cgttgaagcg gccacgcaac gctcgcagga attgggcaag accgagaacc
   130501 atcatctcta acaaggagcg cgtctcgtgc aatattgggt gaaagtcgta tttgccgata
   130561 atcaggaact gctggtcaag gacgccatcc ggcataccat cagtgaggac atggaagtgc
   130621 ttgaggtgga ttcggccaag gaagtcatca ttgtgccgat gaagcagatt aagtacatcg
   130681 cttgcgatgc cactgtattc gctcaaaaat caaagactta ggagttttcg taggcgttgg
   130741 tcacggtttt ggtcacggtt ccagaaccga tttttaacga atccagctta tcgaccgctt
   130801 gccgattccc gcctggaatt agatgcccat aggtgtcaca ggtgatggta atcgacgcat
   130861 ggccaagttg ctcttggaca tatttcaggt tctcgccatt cgcgatgagt cggcttgcat
   130921 aggtatgtcg gacactatgc atatcgagtc gtcgtagtcc cgctttctcc accatcggaa
   130981 accacagttt gtaccgtaac caattctccg ccatataact gggctcccgc ctggttccgc
   131041 ccaggttgcc tggaaagagg acttcaggtg ctgcgtggcc agcggcggcc gcctccaggt
   131101 cctgtagctc gatccattcc gtcagagcct ttgccagacc ctgcgacatg tccacccgcc
   131161 gggccttccc gttcttgggt gtgcccagga ttccgcgcga ccagttacgt tgcacgtaga
   131221 tggatcggct gtgaaagttc agatcgcccc gatggagtcc aagtacctct cctgctcgta
   131281 ggccggtgcg aaagaaggtc agggccattg ggtaaaacag cgggcgatcg cgtcgaatgg
   131341 tttccagtaa caggccttcc tcttccggcg tgaagatcgc cagttctgat tcttcgatgg
   131401 tcgccggccg tttcaggagt ttgccggaac ggagggccgg gttgtgagtg ataagcccat
   131461 cctccacagc ttcggtcaat accgcgctga gcgtgagcag cgcattgagt gccgtatcga
   131521 aatccagccc cttttcaagc agccctgcgg cccatgcttt gatccgtggt cgtgagatgg
   131581 cggagagttg agaggtgcca aaggcgggga gtgcatgttt tcgcaagcgg gactcgtacg
   131641 tcttgatggt cgtaatcttc ttgccgcgtg cgggttggtt tttgagccac gtcacgaagt
   131701 agtctttgag caggattgat tttgtcgtct tctgtttggg aaagagtttt ccctcgcgtg
   131761 cctcggcctt caactttcca tacagcgtgc gtgcttggct cttggtgtcg cacttgtgcc
   131821 acgtctggcg cccctcttcg tagacacgca cccaccaccc ttcgcggcct ttgcgctggg
   131881 tgatgcctct atccttgcct tcttttcttg ccacggtggc tctccttttg ttgttcggtt
   131941 ttgtgattct ctcgccattt gcgcgtcgcg actcgcgtct gacaacgagg gccacagtag
   132001 atttgatcga cacgaatggc gaggtaaatc cgctggcact ccgggcagcg gcgaatgcgc
   132061 ccagaatagt ccatcaacag atgggcaaac cgatattcaa actccttcac tttccgcttc
   132121 gtggccacaa atacgctgcc tttgcgtgcg tcctcgatcg gcaacgtcac aatgatcgtg
   132181 aattggggaa acgtgaaggc agccacggcg tttttccaga gcttctccag gctccccagg
   132241 accatcccct ggatctcttt ggcctctcca cgactgggaa gggtgccacg aaatccttct
   132301 cc
//
LOCUS       DAOQPD010000003       114933 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_44_length_114933_cov_24.158507, whole genome shotgun sequence.
ACCESSION   DAOQPD010000003 DAOQPD010000000
VERSION     DAOQPD010000003.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 114933)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 114933)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..114933
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_44_length_114933_cov_24.158507"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..76)
                     /locus_tag="PK063_01420"
     CDS             complement(<1..76)
                     /locus_tag="PK063_01420"
                     /inference="COORDINATES: protein motif:HMM:NF016245.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family protein"
                     /protein_id="HMZ95721.1"
                     /translation="MHTILLLTISNIFMTFAWYGHLKYK"
     gene            complement(138..695)
                     /locus_tag="PK063_01425"
     CDS             complement(138..695)
                     /locus_tag="PK063_01425"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95722.1"
                     /translation="MPLLIRILIVGFLGLLNGCYVGEGTGYLRFEGKVSNEEGQPLDG
                     REVRIQLSPVESIHVRNVGKVAHTQNDGKFVIETHGIVGVVYVAPIGWIVVPLGVVIA
                     ALTPWTNSEVQDFLRPSYTFGPDCLDHPKIIALKIDSADYGMTFIEKDIVRKLYHGVE
                     RKNGESCARVYDFGELEISMGSLSR"
     gene            complement(1202..3709)
                     /gene="uvrA"
                     /locus_tag="PK063_01430"
     CDS             complement(1202..3709)
                     /gene="uvrA"
                     /locus_tag="PK063_01430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HMZ95723.1"
                     /translation="MSNSIIIKGAREHNLKNLDVEIPRDKLVVMTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLEQMGKPDVDSIEGLSPAISIEQKSTSHNPRSTVGTV
                     TEIYDYLRLLYARVGHPFCFQCGQEITAQTVQQMVDAICELPEGSKFQILSPIVRGRK
                     GEYRKELLEMRKAGYVRARINGEMVDLGEDITLDKQKKHTIEIVVDRLVMKPGDALMR
                     RIADSVETSVKLAGGLVGVLSETGKLHLYSDKLACIKCGVSYPEITPRVFSFNSPHGA
                     CPACDGIGYAMTPGATEEDDFTLLERCETCQGARLKPESLAVRIAKKSIAEITGLSVR
                     AAADFFATLKFTERELVIAHRILKEIRERLGFLVNVGLDYLTLDRPAATLSGGEGQRI
                     RLATQIGSGLVGVLYILDEPSIGLHQRDNRRLLQTLLRLRDLGNTVIVVEHDAETMEA
                     ADYILDLGPGAGTHGGRIIAQGTPKQVKANPDSLTGLYLRGAQMVSLPQRRRTPKGFV
                     TVVGAKKHNLKGVNVNVPLGLLTCVTGVSGSGKSTLVLEVLFHSLSQLLYHKKPKIDG
                     CKEIKGVDALDKIIDIDQSPIGRTPRSNPATYTGLFTFIRDLFSNLPESRVRGYKPGR
                     YSFNVKGGRCEACQGDGLIKIEMHFLPDVYVTCEVCKGQRYNRETLDIQYKGRSIADV
                     LNMTVDDALEFFENIPFIKSKLQTLHDVGLHYVKLGQSATTLSGGEAQRVKLSRELSK
                     RPTGRTMYILDEPTTGLHFADIQRLLDVLDRLVETGNTVLVIEHNLDMIRNADWIIDL
                     GPEGGDRGGEIVAEGPPKEIAKVKRSYTGQVLREAGV"
     gene            3912..4703
                     /locus_tag="PK063_01435"
     CDS             3912..4703
                     /locus_tag="PK063_01435"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95724.1"
                     /translation="MHDVLSLFKRNINQLFGITVDILNVGRSLQQLSLSMQILANNGV
                     VQAAKIPGGKGRPMLALVEILNNTPKEIRPEVEALEHLCAGLAKVTASSSNIVWRYHQ
                     LIASLLSAMTQGELSSKSKSLETLSHLRFTTAADVTQLTQHPAFTAVGGLERENRLYL
                     VHHCQANLTELQERLKEALRCLGETHQALNGLKMIGLTARYMAFCISSEAAGLAEAEA
                     NFKNLAAEISRVVDDLDNKTRAMKDAIEHGQELLGLLLKGHTYAK"
     gene            4693..5472
                     /locus_tag="PK063_01440"
     CDS             4693..5472
                     /locus_tag="PK063_01440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HMZ95725.1"
                     /translation="MQSKVLFNKDDHQWVVIGRDPEKDDHVIDTNEYVIIHRGHAMLL
                     DPGGIQIFPQVLAELAKYVRMQDIKVIFASHQDPDICSSLAMWLDLNPAIKTYCSWLW
                     TGFVSHFSTGAVITLNPIPDDGMRIKIGEEGPEMEAVPAHYCHSSGNFSLYDPSAGIL
                     FSGDIGGALVPDHHASLLVTDFEQHIQYMRGFHLRWMPSTTALRGWVQRVRAIKPKMI
                     CPQHGSIFEGENVGKLLDWLESLEVGQWKGSAPKSETRAAA"
     gene            5566..6333
                     /locus_tag="PK063_01445"
     CDS             5566..6333
                     /locus_tag="PK063_01445"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014962022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HMZ95726.1"
                     /translation="MVRAEQSPITEPAAKAVSTWSGQAREQAVQRMFTAIAGVYDLNN
                     TLLSFGLHHHWKRLTASYVPTVTNGRALDIGAGTADLALLIEPKMGERGHVVASDLNH
                     AMLAEGLRKVSGRGLLDRITCLQANAEQLGFPDNTFHAVTTGFCMRNVGNLTQAFTEI
                     RRVLRPGGRFVCLEFSRPAYGWLRALYDWYSFRLLPWIGTRVARDRTGVYEYLPASIR
                     TFPDQERLATLLREAGFREVEYRNLTGGIVAIHVATK"
     gene            6400..8043
                     /locus_tag="PK063_01450"
     CDS             6400..8043
                     /locus_tag="PK063_01450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HMZ95727.1"
                     /translation="MNSILYIFLPCKKVYPIGVTYLADFIHRRKPEVRQRILDLSLFS
                     ESQRTQAIRDAALEFKPDLVCFSWRDIQIFSPHEGDASLEHAFNFYFASNPIKRVAAS
                     FAGLKQLYRYYSHIRANLSYPWLIRKEFPKTQIMIGGGAFTAFADQLIEKLPEGTIGI
                     LGEGEDAILKVVNGESLENERYIIREGKQTRKGNQGSPALLDALTVDLPYLTSIFPQH
                     ASYMDESIGVQTKRGCPYDCAFCLYPYIEGKRVRYRPPEMVVKDISQHYHQWGARRFW
                     FTDAQFITGKEAYPQCTEILERILSEKLEIEWSGYIRTSLITPELAKLMVRSGVGDLE
                     VAITSGSQEVLNNLHMGFKLERLYDGCRYLAEAGFKGKVILNYSLNSPKETEESLLQS
                     VESYKKVASILGEERVFPLMFFLGIQPNTDLEHRLLEEGYLSAGYNPLMLTPTSIRKL
                     LYNPAPLNKIIAKACLTAWEQKEGSRDPRTWTGSLSQTPPAGAKPDQAHYADANLIRG
                     IQNNSGREALLTLEEILRSRRPAQPTAAATEKTAVSPTS"
     gene            8209..10317
                     /locus_tag="PK063_01455"
     CDS             8209..10317
                     /locus_tag="PK063_01455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HMZ95728.1"
                     /translation="MYKTIYIPVDNSDHSNTAVDVGVELAKTYGSKIVGSHVYAAKMH
                     DKRFKQMEAGLPEEYHDEKELDRQRQIHDSLITRGLQIITDSYLDYVDKKCNEANLPV
                     ERRSLEGRNWKVLAEDINTNAYDLVIMGALGVGAVKDSVIGSNTERVLRRVRNSDMLI
                     IKQPTPVGTGKIVVAVDGSPYSFGGLMTGLALGKAFNVPVEVISAFDPYFHYAAFHSI
                     SGVLNEEAGKVFRFKEQEKLHEEVIDSGLAKIYQSHLDISREIAQAEQTDVKTTLLDG
                     KAFEKIIQYVRKENPWLLIVGRIGVHSDEDMDIGSNTENLLRSASCNILVSNRKYVPP
                     IDTQAEYTIAWTEEALRRMERIPVFARGVAKTAIHRYAIEKGHTIISNTVVDSAVGHI
                     LPKGAMDAMRALGGNLDAAGIDRDKMQADDSVAQDLMGSTLSGMMTQVVEEKPAHSPG
                     TQAYLDRMSQNYFVCDGCGYIGKGDTPVKCPVCSAEGDRFKQVDKSIFEAAAKAEGGL
                     ETDVAYDDIPMQWTKDAKEAIRAVPAGFQRRRAKAKIEKSARKLGMTTITLEYANPMI
                     QEAASEDYTPIFANKGTGTAGQPSAEVPTANGTESATANGNGTEQPQASQAPSSPYTW
                     TPDAQGRLDRAPEGFMRECTKALIEKHADKIGTTVITLEVATEGIEQAKGYMADAMKT
                     GNLKDMIANLTGSSKTGANR"
     gene            10317..11720
                     /locus_tag="PK063_01460"
     CDS             10317..11720
                     /locus_tag="PK063_01460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HMZ95729.1"
                     /translation="MGKSLPVLNIPFLGDKLESLQQQISKFISPTSPGTAPNDGRTVD
                     DFKPYLVALNLTKRCNLKCDHCYLDATTKAGGGSDELSTEECFRLIDQIAEVNKGCLL
                     VITGGEPLVRPDILDIARHAVGLGFIVVFGTNGMLINDRMAKTLVEIGVMGVGISIDS
                     LNPEKHDHFRGVPGAFASALAGIEACKRNGLQFQVHFSAQPMNYQELPAVVEWAHTLG
                     ARVLNVFFMVCTGRGEELTDITPQQYEEVLGYLVDCQDQYKDMLVRARCAPHFKRLAY
                     EKDPNSPLTKATGYMGGGCLAGTNYARVTPNGELTPCPYMPLSAGNVRETSFADLWER
                     SDVFNSFRYPQLKGKCGDCEYTDICGGCRARPYVDHGDWLDEDQWCLYTPKGGDKIKV
                     AFNTPEESEVAWDEASELRLSRIPYFLRAMVKKGVERHARENGIALVTIELMEELRKK
                     RFGNDAPVFNFDMRGKD"
     gene            11787..12302
                     /locus_tag="PK063_01465"
     CDS             11787..12302
                     /locus_tag="PK063_01465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95730.1"
                     /translation="MDSVQSIFLDLNQLIPIVNHWFHLLSAVIWIGGLAFIVMAVKPG
                     LAEAALPKEYVRPITDAFYKHYKRVAGVLLVVLLFTGGINLHYVNQIFVSQTGQGMQH
                     HPKYLWIFCIKLILVLCLLTLFLYTVIFKTDQDEEEEGENYESIPFQRAALWMGFFII
                     LCAAAMKHLHQ"
     gene            12623..14401
                     /locus_tag="PK063_01470"
     CDS             12623..14401
                     /locus_tag="PK063_01470"
                     /inference="COORDINATES: protein motif:HMM:NF040606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="di-heme-cytochrome C peroxidase"
                     /protein_id="HMZ95731.1"
                     /translation="MRTRLYRSFALTALLLTLSPLHCRAIDPSPNQISAESLNQSLSD
                     QDLQQWYHLSAGTQLIPYDWLVALLDESLAKTFAVTGLVEDPRHPDKLPVGFAKTEGP
                     NVPVPLVGFTCSFCHTTQFRYKGHSIRIEGGPSLQNNAALVNALIQRLGALTPPDVSA
                     FLNSLKAEAPPDPFKTFANRVLASRGEAVTAYTLTKLAQDVRVLTQALVSRSGKDISP
                     QQWGPGRFDALGRGGNTVFAPLNPDNLRPANAPVSIPALWGVWEFDWVQWAGSIQHPL
                     ARNIGQVIGVNAGLFSWARPGVPTPSDKNKVFHSSIDVTSLTILENLARRLPPPQWPS
                     VFPPINRELAARGKDLYHGNKAKGIPNLCAHCHVPSKMSHSSANSPSLQITMVPLQEI
                     GTDSLYLENFSQRTVDTSFLGRGRISAREASEYVTTELMTLDKTGDLSSYRDRPNIWR
                     DKAQYIARPHFGIWATAPYLHNGSIPTLYELLSPARERRACFVLDPNMEFDPEKVGFV
                     TGDCANPSQSPTLPPRLEFRTALPGNSNRGHEFANTPDCDSAKSNGVLGCELPVNDRL
                     AVIEYLKTCDLDRLILPNAPACPNFD"
     gene            14470..17187
                     /locus_tag="PK063_01475"
     CDS             14470..17187
                     /locus_tag="PK063_01475"
                     /inference="COORDINATES: protein motif:HMM:NF024583.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ95732.1"
                     /translation="MTDLLSSDHSILERPFMEFRPFGLNDKGEKISDISGVVVQSNVD
                     YMCDYLSRTAGSQAAAAAVDELCRLLNARLPDRTYHVTPDFLRNIWNSYSYEFVCYLR
                     EFCEQLSGDPQFHINVGTDRKVPPLIQILCRPFSTQQLYKMWPYFGRKYVRDVLEFEV
                     GRVTRRSAVLRMTFTERALVQFGPYRKRCVDVICLSCKSSIARVQTQLHGTPAATVKD
                     LSCTAHGDAYCEWEFTWTPQVRSSIPVAMWTLVAGGTFTYLHVRWPDVPTFEALGLAA
                     VPASLLWWMITSHMRQATKPLQRLIKDQEQVVDARHEELREAYLEQQSTAVMLRRKVN
                     DLTTLHRAGLLFSSTFDREELLTNVLDTIVRDLHYDRAMITQFDRTRQVSHDFRVRGM
                     PQEVADFLRTQEVSVTDPETVEGAVFLRGEPVLTNNVHEIWDRLHPFDQKLIAMVNVK
                     SFITVPLKTHDAVIGSLSVDRTHNQALTQDDLDMLVTLASQVAIALDNAQAYREIEAL
                     NAGLEVRVRERTAELEAANTQLKQMDRLKSKFLAHVSHELRTPLTSIVGFADNMLEGL
                     VGSLNMKQEQYLTRIRANGTRLARMITDLLDLSRVEAGKLVLSFDHVALQTVVSDVIE
                     QLLPLAIAKHLQIELRSPDPALLVWADPDRVSQILTNLLDNAIKYTPDGGHITVDLSV
                     GDHEMARVVVRDTGQGIPADALPKLFDPFFRVHHQERSQTKGLGLGLAIVKDLVDLHG
                     GSIMVHSTVDEGTEFTFTLPLDSRAPEPAAQVPAARRRLLVVDDDADICDLLRDRLES
                     EGFHVDTAADGRTALRILAETPVDGVLLDIALPEVDGFEVLRQLRPQQPALPVVMMTA
                     VEALDRAMAAVEAGAQGYLLKPFDAARLRQIVDHWFLAGASKTDPTSGR"
     gene            17192..18580
                     /locus_tag="PK063_01480"
     CDS             17192..18580
                     /locus_tag="PK063_01480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein transport protein"
                     /protein_id="HMZ95733.1"
                     /translation="MLFSRRFRIALVLSLVLLPVSLSLSVTPVQAQTPRLQGQSASAA
                     AMGNAFVAQADDPSALHYNPAGMTQLHGFQTLFGTSLIGGTTQFTGPSGAQATGDRNG
                     SLAYPPPGHVYLVANLKDLGFAALGDFSAGIGLNNPFGSLTRYPNDGPFRSALTFTTL
                     PLLDIKPTIAYKLNDQLSFGLGADIYTFSGLFGEGHLEQKSVWPGGLGIPAGSLVEIN
                     GSDTTAGFNVSLLYTPYRNSEGKPLVNIGMVYRSQATFHLTGNFLANGTSIAGTAATF
                     VLPQVFSGGIAVWPVRTPDREWKLEFDVDYVGWKSNRTLDIHLTNGTVLPFPQNWQSG
                     YTAMVGTEYRWLRLASLPDWDVALRAGYMNQQTQVPDRTFNPGVPSANTHIPSVGIGF
                     ACHEHGYFLGLIRCGELGIGPLKPKLFAIDLSYQAAFYEVRTVTGNQNPTVNGRYDTL
                     IHAGSLSLRFNY"
     gene            19578..23075
                     /locus_tag="PK063_01485"
     CDS             19578..23075
                     /locus_tag="PK063_01485"
                     /inference="COORDINATES: protein motif:HMM:NF017658.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="filamentous hemagglutinin N-terminal
                     domain-containing protein"
                     /protein_id="HMZ95734.1"
                     /translation="MPGLCQAQPSSPITSSGLNTTVTTSGNSFNITGGTRPGGGTNLF
                     HSFGEFGVPANQVANFLNDSGLATTNILSRVTGGTPSNIFGTIQTTGFGNANLFMMNP
                     AGMVFGPNASLNVGGSVHFTTADYLRLGDGARFNAMPGPQDAAVSSAPVAAFGFLGSN
                     PSAIVVQGSQLTLAEGNTLSLIGGNVQIANGTLSDGAIQPARLSAPGGQINLVAVGSP
                     GEALISNGAGTLAEPMLTGFTGLGTISLSHGTTIGTSGDAAGRIVIRGGHFSMEDAGL
                     EAISTSVSPNSLPSSSPRGDISIQAEEVSLSNGAHLLTSTINGTAGNIALEVGTLRSN
                     VGPGGLPLSGAAPVTITSSSTGLGGPGSISVTGNGRAASDVVVLSNTQAVTTVPHSAQ
                     PTIVPAHIDMTAEHLELRNGTVLKTDTTGGADAGSITLKVGTLATEAGPDGRVLLSSS
                     SNCGTGCVGGQAGDITIQGIPGITPAETHLYVPIVRPDSPPTVAISYQLARNMDLRGT
                     DIRSEAIGNAPGGQVIMRAQGSISLADTTISVATQDFQIDGPKPSGELVRNQGFSRID
                     ILAHDVTLKDSTVRADANVSDIGSCPLCLGGPSAGEIWFRVGNSFTADNSAIINSGKG
                     RAQAGLTKIIRDHFFSFGAIWEPDYPDYPTNSITLNHSQITVESPHSGIPGYLRLRAD
                     NVTLNHSILNSQVNDVSNSRGLDGQLIDVPGAGERGRVIADGRDVQGSVLVSAKTLDI
                     TGGGIIAPTTGSRIASRIELLANELTTHRGTGPGGTFDAPRILDAADPTRVVLSSSST
                     GSGGAGRISIAGEGVAMPEGTPYRPASSIHLDGTALFTDTHSDALGGKIEMISRGPIV
                     LHDTTVSANVTDVRPASAGLQEQGGNISLSAGSLLVQGGGLSALSRGTQTGGNIAITV
                     QGPITLESGAAISASNTGSANAGSVTIHAGSEFVSRDASVTTESIHASGGNIFIQATD
                     SIRLVNSRISTSVLGGPNSSGGNIILDPAVVTLQNSQVLAQAVQGAGGNIRIIAGTFL
                     ADQTSAVSASSEFGLNGTVSIQSPVSSLSGTLATLPQSTLQTQQLVTQRCAAQGSGHL
                     SSLVVAGRDVLPVEPGGWLMSPLSVFAVDAHDDGGRPVAETIPDAAEGGNTLVELTQE
                     HPTPEPRSNFTTPGGGCRS"
     gene            23176..24873
                     /locus_tag="PK063_01490"
     CDS             23176..24873
                     /locus_tag="PK063_01490"
                     /inference="COORDINATES: protein motif:HMM:NF015803.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ShlB/FhaC/HecB family hemolysin
                     secretion/activation protein"
                     /protein_id="HMZ95735.1"
                     /translation="MTFQALAQVAPPLPPIFDPTGKSGKPPALLKEDFNTPPSEPPSS
                     ILPKVPTTPPALPDNKLGAFRVFVHDIHVTGSTVFSETELSEVTAPYRNRYLTTEDLE
                     KVRLALTLLYVNNGYLTSGAVVPDQDVTFGTIVIQMVEGKLAHIDVEGNAWFRNAYLR
                     DRVARGVSTPLNIHPLQERIQLLQQDPRIERINAELKPGDVRGESVLNVRVKDANPFR
                     AWLEFNNHQTPTVGAERGLATVAHQNVTGHGDQFMFTYGRSHGVNPIIDTSYSLPLNR
                     YETTLTAYYRRNAFLVVENPFRALDLNVDSQVIGLALRQPVYRTVTAEFALTLTGEHL
                     FLKTTSAFDAPGLPSLFIPGSSTTGVATVSALRFSQEYTHRSSSLVFAALSRVSVGLN
                     VLGATINSGPLPDGQFVSWLGQAQVVKRLDDWWGVQLLGRVAAQLASDRLFPLEQMPV
                     GGRFSVRGYRENTLVRDDAVLASFESRVPLLRFPSGEDRLQFAPFVDVGHAWNAKGHT
                     PDPHTLASVGAGLRWMILPQERARFEVYWGQQLNHVRGGEGNLQDHGIHLQLVVQVL"
     gene            24874..27216
                     /locus_tag="PK063_01495"
     CDS             24874..27216
                     /locus_tag="PK063_01495"
                     /inference="COORDINATES: protein motif:HMM:NF024180.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAT domain-containing protein"
                     /protein_id="HMZ95736.1"
                     /translation="MRHHRLTVFPPPSHLLRYGLKGLSLCLIIFFCCTVSLAADSQPS
                     AGDLMQRGRAAAREGSYEEALLAWKAAAELYDQAGETKNHIQALTQSAFAARTLGHIN
                     QAFLQEELALHLARQLRDSQWLVITLSELGKTYVTNHQYEVAADYIGQALEIAQAQSF
                     RALSPALQNDLGIVLALQGRPEEALAAFHQCAVSAKQEGLIPLFIRARVNAARMAIQV
                     AQFDTATSALAEAADQLAGSASSYEKAEGLVNLALGYRDLALAHSGSHASALKRSALF
                     LQEAAGMTQHPGDARLASYVYGHLGHLYEVERRFDEALQLTRQAVFTAQSARAPESLY
                     RWQWQCGRLLNRLGQLDDALSAYQEAAITLHPIRSEVTFAVQTSPDSHQPSIRALYFE
                     LADLLLRRAALMHENREAEAYLRAARDVIEAFKAAELRDYFRDDCVDQMQARITKLDA
                     LSPSTAIIYPIVFSDRTELLVSLPDGLTRHSVPVTAATLTDEVRRFRHTLEKRTTREY
                     LPHAQQLYDWLIRPLDPDLRRLQVNTLVFVPDGSLRTIPMSALHDGKEFLIEHYAVAM
                     SPGLDLTDPQPIDRAKVHLLSSGLTKAVQGFPPLPHVADELDSIRALFKGEQLIDQEF
                     LTPRLEEELKGGRYSILHIATHGQFAPDVNQSFLLTFDARLSMTQLERLVGLFRFRRE
                     PLELLTLSACQTGSGDDRAALGLAGIAVKAGARSALATLWSINDDASSELVSEFYRQL
                     HDASVSKARALQHAQLKLLSDRVYEHPAYWAAFLLLNNWL"
     gene            27265..27972
                     /locus_tag="PK063_01500"
     CDS             27265..27972
                     /locus_tag="PK063_01500"
                     /inference="COORDINATES: protein motif:HMM:NF017829.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF928 domain-containing protein"
                     /protein_id="HMZ95737.1"
                     /translation="MARTFVATLLFTVSLVSTNAAAPEGVPDVPQYNAPQKMTPRARL
                     GGSLRGSEGEDPAVAALVPDHVGITVKQHPALNWFLSKHTSLPITFTLIDERSIHALV
                     ERPLAPPHQAGVHAVKLEDLGVTLQPNIQYRWYISVIKDADSPSQDIVTGGMIERCEF
                     SECSILGAMTTCTREAVMTSAAKGFWYDAMGCLCDLIDSNPADTALRKQRAALLRQVG
                     LHDVADWDLAQSHARQG"
     gene            27976..28716
                     /locus_tag="PK063_01505"
     CDS             27976..28716
                     /locus_tag="PK063_01505"
                     /inference="COORDINATES: protein motif:HMM:NF017829.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF928 domain-containing protein"
                     /protein_id="HMZ95738.1"
                     /translation="MPYRRVSFPLVLMIAWLTGGYASQFPFGAPDSIAADPLVPLELR
                     LPEYKPKKADAPRARIGGHSRGTEAGAPVLIALVPDHIAFTVKNDPTLCWYQSLHTSR
                     PMVLTVVDSRGIRPVLEHSLPTPVRHGIQCLRPREYGVEFRVEESYRWYVTVVMDPNR
                     PSLDVVAGGMIERLSLDEACALGMPCPSSSCDTDGIYRYAESGLWYDAIACLVELLEQ
                     ESDKDRLRLMLDHLLHQSGVHLPGESSP"
     gene            29099..29224
                     /locus_tag="PK063_01510"
     CDS             29099..29224
                     /locus_tag="PK063_01510"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95739.1"
                     /translation="MELVMGGLLVGVSGMLAVLIVAVWKDSASHRTGAHPSHRRV"
     gene            29965..31920
                     /locus_tag="PK063_01515"
     CDS             29965..31920
                     /locus_tag="PK063_01515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HMZ95740.1"
                     /translation="MSVCWAFAIEAHSPIPTYAAPQADAPANEELELLKEEETVSIAT
                     RHEQPISQAPSNVYVITDEDIRHSGATDIPTILRRVPGLDVMQVTGADFNVSARGDNQ
                     LFANKILVMVDGRSIYIDGQGLVFWKSLPVTLPEIKRIEVLKGPASVVYGFNAFDGVI
                     NIITKSAQEMKGTTLQFGGGELGTISSAAVQAGSAGKLDYRLSIGHDQNQQWRNNDAL
                     AFRSNKFNAQTQYNFSGDAILRVAGGFIDTNRFDGPVSNVQVPRSQFNQGYSDVHYQY
                     RNFSLRGWWQGNDIPVESSTHPLLAPFVRQTNATGGSNVSFTTNTYNIEAQHSLDFGP
                     ANRLSYGVNYRYNSVDGAAVSELGREDRLGFHLQDEWKILSSLTLVAGVRYDLHTRIN
                     GTWSPRVALIYNLTPEHTFRVSGSVAYRPPTLFESNLDLRILPTVPPLFAPIPLFGSQ
                     RLNPEQIISYEAGYQGWWLKHRLRTRLDLFFNHLSDLINFQTIGATRTLVNGGEADIY
                     GTEAGFEFLATRWLSGFANVSYQKIGQTFTGVSRRGGPDWKANVGLRGDWDNGLNGEI
                     AVHYVAGATYPLIELFTALAPVLPAPISPNIDSYTLLNLRGGYRFWHEKAEVAIAVYN
                     ALNDRHKEHPLGDTLGSRVMGWLTLRY"
     gene            31957..33990
                     /locus_tag="PK063_01520"
     CDS             31957..33990
                     /locus_tag="PK063_01520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HMZ95741.1"
                     /translation="MVAAFMTVSISQFAAAEPPAIRVEDSLTVPANNDLELLKEEETV
                     SIASRYEQPISQAPSNVYVVTDEDIRQSGATDLPTVLRRIPGLEVMQMTGADFNVSAR
                     GDNQPFANKMLVMVDGRSIYLDVQGNVFWKSLPVTLPEIKRIEVLKGPASAMYGFNAF
                     DGVINIITKSPEEMKGTTLQFGGGEQGTISSAAIQAGTVGKFGYRLSIGRDQTQQWRD
                     GDALAFRAHKFNVQTDYALSSTSKLQLSGGLIETNRYDGQVGEVTSNSIRPSFGYANA
                     VYEHGAFLVRAWWSGYTDHATINPLPQLAGLLSVTDRNGVSTNPFSGNTYNVDVQHAL
                     DMGAANRLLYGANYRHNSLSSPAIDQFSRENRLGLFLQDEWRASSAITVVAGIRYDLH
                     SQINGTWSPRLTLLYQPVEGHTFHLSGSAAYRPPTLFESHQDQRVTTNIPTGLPFPLP
                     SSVSSTVPVTGSTGLAPERIISYEAGYQGWYWKHRIRVRADLFYNHVSDLIGSRITAS
                     GSSEFVNDPGSADIYGGEAGIEVLANRWLSGFANYAYEEIGQSFTGTVRRGAPRSKVS
                     AGVRTEWDNGLSGELSYYYVGAATYPLAQSFTQLGTIPGAGITVPGNQVGSYNLLNLR
                     AGYRFWQQKAAAGYMRDAEVAISVFNALNDEHKEHPLGDLIGRRVMGWLTLRF"
     gene            34021..37143
                     /locus_tag="PK063_01525"
     CDS             34021..37143
                     /locus_tag="PK063_01525"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ95742.1"
                     /translation="MAPATLTHSILVVDDDPDIALGLQDFLDHDGYQVNVAMTCAEAL
                     AQAHAHHYNAVLLDLGLPDGDGSSVLLTLHQQQPQLPVIILTAYTSTDRTVGSLTQGA
                     FAYLTKPYNRDELRAVLQRAVGVQALAVKAEHAEHALHESEARFRSLVEAATDSIVLA
                     DHNGHILSWNRAASHLFGYTDEEVRGQSLSILMPPRHRAAHERGLARVRDTGESRLIG
                     RLVELEGLRKDGSEFPLELSLAMWKSDEAVFYSGIIRDITQRRRAEEILDRLRHLHEV
                     ILTQAGEGIYGLDRDGITTFVNPTAAELLGYEPFELIDRPMHGLLHHSRSDGSPYPSG
                     ECPIYAALHDGLVHRVSADVFWRKDGHPVPVEYVSTPIIEKGRTAGAVVVFRDISERK
                     EAERAVEESQERFRQLAEHIREVFWITNPEKSHVVYISPGYEEIWGRSCDSLYAHPTS
                     WLDAIHPEDRPRIEEAAISRQALDVYNETYRILRPDGSMRWIWDRAYPIRDASNQVYR
                     IVGFAEDITEQKRIEAELIASERRYRVLFDDNPSMYFMVDAVGTVLSVNRFGAERLGY
                     EVQDLVGTSVLNVFHPEDQQAVLHNLSDCLSEVGQPKRWELRKVRKDGHVIWVRETAQ
                     AVRGHEQAPVVLIVCEDITAMKEAEIALHDSEELKNQILHSSADCIKVLDLEGRLQYM
                     NDAGQTLLEIKDLGTYTNKPWSEFWEGDDREAALAALEAAKAGDIGKFVGFCPTTTGQ
                     AKWWDVQVTPMLDTQGYSRRLLAISRDITAYKQVQESLHASEERLEHVIRGSHDGFWD
                     GHVLPDHPWYAPITPVWWSPRVREMLGYNEEEFPDILDSWMSRLHPEDREAVFERLNA
                     CMEQGVSQYDVEYRLLNKQHEYQWFHARAEVVQRDAQGQAVRMAGALQDITDRKRTEA
                     RLRLSEERLRMALTSSDLGIWDWDVTSDRLYWSEGVELLFGLAPGSFPGTYTDYIGLI
                     YLLDRGSTLTRLELSLRDQTSVHIRHRVVWPDSSIHWLAWSGRIYRNADGVATRVLGI
                     VHDTTGRMDE"
     gene            37276..38169
                     /locus_tag="PK063_01530"
     CDS             37276..38169
                     /locus_tag="PK063_01530"
                     /inference="COORDINATES: protein motif:HMM:NF016292.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HMZ95743.1"
                     /translation="MVLLLWTLLIASPALATDVIILKSSDIAAYNQAINGFKAAIPAG
                     INLSEYDLQGDLEKGRKLARKIRASDPSLVFAVGLKAAKAAQLEIVDIPVVYSMVLDP
                     AKYGLNAQNMTGVLLEVPAERQLVMIRNLLPQLKHIGTLYDPAKTSTLIDEARRLLKQ
                     SGTELAPMQISSERDVPGSLRALLPSVDALWLVPDSTVLTDESLRFILNTALEARVPV
                     IGFSREFARSGALLCLSVNYADIGRQAGQLTRKLLEGQLSLPLKPWHPDRIETSLNLK
                     TAKFLGIDIPRELEQKADELY"
     gene            38169..40481
                     /locus_tag="PK063_01535"
     CDS             38169..40481
                     /locus_tag="PK063_01535"
                     /inference="COORDINATES: protein motif:HMM:NF024583.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ95744.1"
                     /translation="MKGPSVKDPAHLAAPPFLPNGLKRFVSLRTKFVVFFSLIIIFTC
                     SGMSWYFIHSKRVAMTERVQDLGSILVKNLAHNVRYGIILEDRVILEQFIDGVLGVDE
                     VVYAQITGADGQVLAAKSKGKLKTPLGTVRAVDQPFYPSAAIAASLIRHPLPEPTVTR
                     LRLIGESSLPFEEQDATLRVSTAGMREETFYDFALPVLKRAEPRLEALALQEEETHKT
                     RTAASTAPAFGVVQIGLTEVPMQRELAEVLRTFLLLTLGIITAGILSTNLLARRIITP
                     LRNLAAGARKVGEGDLSTFVVPTTQDEVGQLTALFNVMTKSLQERNQAISANLETIRR
                     HVTQLTTLNQSSAAITSTLDLDRLLSTVLQLLSENLGFARMVLFLWDSERGVATVGQM
                     LGMPPEAEEAARRLVMPVHEDGGFAAEILLHGKPVLVPNIETVADRISPAVLPWLRQV
                     GLSSFVAAPLRSQQRILGYLGADRGAQPCTQEDLDLLVTIASHVAVAVDNARAYTELA
                     TLTEHLERRVEERTHELQSVNERLQDHDQRRSKFVSVASHELRTPMTSIKGFVENMLD
                     GLTGQLSERQEHYLQRVKHNVDRLTRIINQLLDWSRLDVGRIDIKPESLSIDAFVRDV
                     VESFQTLAAEKSITLDVLPCEQPLVVYADRDKLEQILWNLVGNAIKFTPHAGHVSVQC
                     TAHDTHSVQITVADTGCGIAPDELPLVFNEFSKVESAMPTSQGAQLGLFITKSLVTLH
                     GGQMWVESRLGAGTQFSFTLPLSATQPAQP"
     gene            40648..43452
                     /locus_tag="PK063_01540"
     CDS             40648..43452
                     /locus_tag="PK063_01540"
                     /inference="COORDINATES: protein motif:HMM:NF024583.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ95745.1"
                     /translation="MAFAAWVLRTSTNTGCFTRQRGPTVHTAVLIVDDDRDIRESLTD
                     MLRHEGYLVESAGSGNEALSHAKQRQYGAAILDIQLPDLNGLSVLKVLMELDASLPVI
                     ILTGNATSENTIGSLAKGAFAYLTKPYNAQELKAVIRRAVSVKGLAVRAEHVEQALHA
                     SEERFRALVESATDAIVLADHYGHIIWWNGAAERMFGYSKREALGQSLAMLMPERFRS
                     AHETGIMRLTTGSAAKLIGKTVELVGLTKAGDEFPIELSLASWRAKEGAFFSGIIRNI
                     TRRKKAEESVVRLSHQNALILDAAGEGIFGLDLEGRTTFVNATAARMLEWSAAELIGK
                     PLAPLLYRLHDEGAEYVQDPLCLSAAVRDGAVHRVQNDVFTSKSGVSFPVQYVTSPIR
                     EQDRPVGVVVVFQDITARKQLECLQQAQLSISHILAQTSTLEEAVPQLLRVIGEMGPW
                     EMTIFWHKEPMNERLVCEGTWMRSSCRWDEFATICRNSEFPPGMDFPGVVWSTKLPLW
                     IPDALTDARFTRAPTAARLGIHGACLIPIRTGTVIHGVLELYADKPRLPDRQLIHILT
                     DTGMKIGQFIDRAQAGSALRATHRMTQNLLASLPGAIFLCARDFKIQYANTLAHHYFA
                     VGGASLVGRPLFECLALSEAATQQLIKEWAALNADSPHQAPERECEVASRLYRYRFFP
                     VATPESAQYQVGIVLWDVTDDKHLQDQLIQSEKLTSLGTMVSGMAHEINNPAQAILSM
                     AELIQEEKDPAVIKEFAADIVGYARHVSNVVRDFAGYARSAGRDGETEIDVAERLMEA
                     VKMARRGPHFGYVDVVTRFDAPTFLRARKSELDQVFVNLINNATQAMDGKGRLTLGAA
                     QDGAWIDVTISDTGPGIPAAVRPRIFDPFFTTKAPGKGTGLGLSIVHKIVTRHAGTIT
                     VDSTEGEGTTFRLRFPALLQ"
     gene            complement(43495..44256)
                     /locus_tag="PK063_01545"
     CDS             complement(43495..44256)
                     /locus_tag="PK063_01545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2OG-Fe(II) oxygenase"
                     /protein_id="HMZ95746.1"
                     /translation="MTQACASSVTEAVERAISALDLDRLERDYWEQNEFLYIPQFLPR
                     EFVEAELASQAQVLKSGLNRNYIPGHKKGGSVSYYTVREQAPQFMDLYRSDAFRAMLN
                     QLTRVNLLLCPDNDPHSCALYYYTEAGDHIGYHYDTSYYKGARYTILLGLLDQSKQCR
                     LVCDLFKDVPGKQPVHMELATAPGDLVIFNGDKLWHAVTPLGEQEERIVLTLEYVTNP
                     DMGAFKRLYSNLKDSFAYFGLRSVFKRAYSSRSRA"
     gene            complement(44472..45194)
                     /locus_tag="PK063_01550"
     CDS             complement(44472..45194)
                     /locus_tag="PK063_01550"
                     /inference="COORDINATES: protein motif:HMM:NF015510.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_process: GO:0042953 - lipoprotein transport [Evidence
                     IEA];
                     GO_process: GO:0044874 - lipoprotein localization to outer
                     membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein carrier protein LolA"
                     /protein_id="HMZ95747.1"
                     /translation="MMRTGLLIAVLVVSAIPAAAQLVKPDEPAVDLQSLHEVQEVVKN
                     IQSRYEKTKDLQASFTQKTRIEGFSTPVISTGHFYIKKPGKLRWDYIEPATEEIYVNK
                     DDVKMYVPEHKQVLVGKLTYMAASQAPLQLLQGVAKLDEEFDIEPMPNKERGAGGILL
                     VSLTPKQGRAEPERAIQKIVIEVQPKTYFLKTIALHEVSGNVATFEFSELKPNSGLKD
                     DLFDFKAPADVEIVRAPVLSRP"
     gene            complement(45191..47632)
                     /locus_tag="PK063_01555"
     CDS             complement(45191..47632)
                     /locus_tag="PK063_01555"
                     /inference="COORDINATES: protein motif:HMM:NF013727.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015616 - DNA translocase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HMZ95748.1"
                     /translation="MGVTTTAKRGDARSAPSRSSHVKREVIGVLLIAVGLLILLSLVS
                     FVPGDAKSIGASGAAGNQPKNMIGSVGALSAAACFFMVGGAAYLFPILLGLLGARCFT
                     PIPLTMRLRNAGSGLAAMVFLSALLHLEVTAVPTISSGWVNRGLAGGIIGQVLADGVR
                     SYFATTGAHIVVLTGLMVALLFTVPVSLTALLQRIPDWWIAARERMTGLMPEWPVKQE
                     EPMAPPKRARVKVARPAREMEEPELDREVQVVAEAVEQIAVPMIPPKIQPPMKVEKRA
                     TPEDEPAAAVATSPSVSDGYVLPDPQELLSDPSGPIARLSDDELKLQSEILTKALKSF
                     AIEGRVTEVRPGPVVTMYEFEPAPGTKVARIVNLADDLALALKAISLRIVAPLPGKSV
                     VGIEVPNPNREMVSMKEVVTSDAFSRSRSKLSLALGKDIFGGAVCADLKTMPHLLVAG
                     ATGAGKSVGLNTMLLSILFSARPDEVKLLLIDPKMLEFQSYDGIPHLLRPVITDPKSA
                     ARGLGWVVQEMERRYKLLAEAGVRSIDAYNRRISELHGAVSDVWQSGKAEQVELTFLS
                     EEERLSKGEDAEPAGDNGPTDSVKPSLPEPLPYIMVMIDELADLMMVAPKDVEDKIAR
                     LAQMARASGIHLVLATQRPSVDVLTGLIKANFPARIAFQVSSKTDSRTILDANGAEAL
                     LGRGDMLYLASGTGKLMRIHGSFVSDDDVRRVVEFVKKQALPSYCRELQSLKIEEAEE
                     EQAKDEVYEQAKDLVLSTGQASASLIQRRLRVGYPRAARMIEQMEAEGVVGAAGRDGR
                     REVLGRRGPVGGDEA"
     gene            complement(47731..48537)
                     /gene="rsmA"
                     /locus_tag="PK063_01560"
     CDS             complement(47731..48537)
                     /gene="rsmA"
                     /locus_tag="PK063_01560"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: protein motif:HMM:TIGR00755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HMZ95749.1"
                     /translation="MAASFPPALKRLGQNFLIDPNIIRKIVSLAALRPDDTVLEIGPG
                     RGALTAGLCAEAGRVIAVEIDPQLQPQLQETLSHCRNLDLRIGDALEFPFDTLPPGTV
                     VVSNLPYYVSTPILFALLDARAHLDRLVLMLQTEVALRLAAKPNSEDYGVLSVLTQEA
                     AEVEVAFRVSANCFRPRPTVGSAVVHLKLKTQDGVDPDRYERFRRLVRAAFAHRRKTL
                     VNSLRDEGYPVERISRAMQAVGVPLQARAETLTLDDYRALATAVDDDESA"
     gene            complement(48554..48874)
                     /locus_tag="PK063_01565"
     CDS             complement(48554..48874)
                     /locus_tag="PK063_01565"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95750.1"
                     /translation="MSDAGSSAATIIDQQVKELDGIEKRTIQDFNTTLGTERVGQWKI
                     RTVALLQQHAGQAEADGLSRKKPGMSFTNDLIEEFSDEVESYRSYLVTLAKRLRAAVP
                     PNAG"
     gene            complement(48893..49936)
                     /gene="pdxA"
                     /locus_tag="PK063_01570"
     CDS             complement(48893..49936)
                     /gene="pdxA"
                     /locus_tag="PK063_01570"
                     /EC_number="1.1.1.262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014960647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050570 - 4-hydroxythreonine-4-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase
                     PdxA"
                     /protein_id="HMZ95751.1"
                     /translation="MARKRSQHSLRPVLGLTMGDPAGIGPEVIAKALADKALTRLCQP
                     VVIGSRPVMERTIKWLDLPLDVVTFDPASGARVKPGQVAVADPLERPLPKFRLGVASA
                     VTGAASIAFIREAVELAQAGSVGGIVTAPINKEAMNMAGFHYPGHTELLADLTKTKEF
                     GMMIVGGPLKIMFTTTHVAIHALSPLLTTQRIAKAIRLAHLGLTKYFGIARPKIGVAA
                     LNPHAGEHGLFGNEEQTSIAPAIKLARATGINASDPLPADTLFGKAARGDYDGVVAMY
                     HDQGLIPLKLVAFGTCVNLTVGLPIIRTSVDHGTAYDIAGKGVAEHGSLLEAVKVAAR
                     LAKSWSPVHSLSR"
     gene            complement(49926..50939)
                     /locus_tag="PK063_01575"
     CDS             complement(49926..50939)
                     /locus_tag="PK063_01575"
                     /inference="COORDINATES: protein motif:HMM:NF013832.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95752.1"
                     /translation="MTVLLYVGMFVASVVITLAGCHLFTNGIEWLGKRLNISEGAVGS
                     VFAAVGTTLPETSIPIIAIFFGAGREQMEVGLGAILGAPFMLSTLVLPILALLLVLYA
                     KLGKRTATFKLNYGEVRVDISFFLVSYVLALTCAMIPSRVLHVAVAAVLLAMYVYYMK
                     LKFSAEDEESEGGDELEPLLFARRSAKPSYLVIGAQGIVGLLGLVGGAHLFVTAANSI
                     SAQLQVSPLILALLIAPLATELPEMSNSFLWLYRKKDRLAVGNVTGAMVFQGSIPVSV
                     GLLGTEWTLGTTALATMVLAVVAMSMSLLQALWSGHWRPWLLSGSALLYLGYTLFLYT
                     HGS"
     gene            complement(50998..52206)
                     /gene="larC"
                     /locus_tag="PK063_01580"
     CDS             complement(50998..52206)
                     /gene="larC"
                     /locus_tag="PK063_01580"
                     /inference="COORDINATES: protein motif:HMM:NF014072.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HMZ95753.1"
                     /translation="MARHLHFDCFSGISGDMTLGALVDAGLPFKDLVRGLASLKIDGY
                     RLTRKRVERGAITATKVDVLIDKGFRAPLTLSQIAKILRRSGLPPAVKERSQAVFDVL
                     ADAEGKAHGVEPSHVHFHEVGVIDSFVDVVGGILGLHLLDIRRVTASAINVGSGMLQS
                     AHGALPVPGPAVAALAVGVPIYAKGPERELTTPTGMALLKTVTTDFGCLPSMQVRQVG
                     YGAGTADPAQWANVLRVFVGDEASESGAMETIVELETNLDDVNPQVYDTVFDRVFAAG
                     AVDATLAPVIMKKGRPGNVLSVLAPREHTEAVLAVLFAETTALGVRIREVQRRVLPRQ
                     FASVRVNGQDVRIKLADIRPGLSKAAPEYDDCKRVAERSGRPVKDILDEALMVYRQTL
                     GTRPRRKGRA"
     gene            52378..52947
                     /locus_tag="PK063_01585"
     CDS             52378..52947
                     /locus_tag="PK063_01585"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95754.1"
                     /translation="MTNSTPAPRVSLKRASTGRTFGLLLLLSGFCLLGDPSLLLAKTK
                     GKSSVPRPEPDLKILSLQAAPMPYRPQEGPFHFIATVQLPKEVDEHLMLEVSALVTSS
                     SMTSLRFLSIRQPVNEHVQTTPSANGDTPQKHVQVDLEWDGLDHNKQQIPIGSYEYEV
                     RVKLLSNGEKGQRTQMLSWPKRGKIVVKH"
     gene            complement(52981..53766)
                     /gene="larB"
                     /locus_tag="PK063_01590"
     CDS             complement(52981..53766)
                     /gene="larB"
                     /locus_tag="PK063_01590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HMZ95755.1"
                     /translation="MNQDQLRALLMEVQQGAVAVPDALHRLRTLPYENLGFASLDHHR
                     ALRQGFPEVIFCEGKTVAQVVAIAKTLLLKNNSLLATRVEPAVARALLRMSKRATYHE
                     AARVVAIVPPKLVRRGSVLIVTAGTADIPVAEEARVTADIMGSKTDTLYDVGVAGLHR
                     LLGQQDRLHDARAIIVAAGMDGVLPSVVGGLVRQPVIAVPTSRGYGAHFGGLAALLTM
                     LNSCAAGVGVMNIDNGFGAGCLAHRINMVSEMDSPKPERAKRQ"
     gene            complement(53763..54788)
                     /locus_tag="PK063_01595"
     CDS             complement(53763..54788)
                     /locus_tag="PK063_01595"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046167 - glycerol-3-phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HMZ95756.1"
                     /translation="MTRSSSQRVAVIGAGAWGTALARHLAEQQISVCVWAHEPEVVQA
                     IDQRRENVVFLPGVRLPATLTATSHLSDALIGADCVIFAVPSHVARLVLSRLGPLLPQ
                     SIPFVSATKGIEETTLELMTQVMQDVLPDHMRHSLMVLSGPSFASEVSQGKPTALCLA
                     GQDAGAVKAIQALFMTPTFRVYADDDLIGVQLGGSLKNVMALAAGVVDGLELGHNARA
                     ALITRGLAEMIRLGMAMGADPRTFYGLSGVGDLILTCTGPLSRNHSVGVRLGKGERLE
                     GILASMQAVAEGVRTAKAALGLAQRCGVDMPIVQEVNAVLFADKPCRQAVGDLMEREA
                     KEEKALS"
     gene            54910..55269
                     /locus_tag="PK063_01600"
     CDS             54910..55269
                     /locus_tag="PK063_01600"
                     /inference="COORDINATES: protein motif:HMM:NF024637.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HMZ95757.1"
                     /translation="MKPCPACGRALPEINRYCTYCGTGVAGDTAQKAMPQASEATRDQ
                     LNLHILYGMVTVLVVSVIMPPWETPPSQPAAFLGFHFILSPPQPDAIVSRLLLTIELT
                     TTAIAGLYLSFLFRSKG"
     gene            complement(55303..56103)
                     /locus_tag="PK063_01605"
     CDS             complement(55303..56103)
                     /locus_tag="PK063_01605"
                     /inference="COORDINATES: protein motif:HMM:NF039614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase-related protein"
                     /protein_id="HMZ95758.1"
                     /translation="MSRLLVCPPEYFQIDYEINPWMRRENAVVPSRAVGQWQTLMHVL
                     EQDVGVGVERMQPVPGLPDLVFTANAGVVASRRVVISRFRYPERRREEVYFAQWFREH
                     GYEVLTLEESLYFEGAGDLLGFPDTWFGGYRQRSDIRSFPKLSEIFQREIIPLELIDG
                     RFYHLDTCFCPLSGGELLYFPSAFDAYGLAAIAQRIPEEQRLVVPEDEAIRFACNAVC
                     VGKRIVIPAGCPRTMRLLESRGYRTHDVELDEFMKSGGAAKCLTLALD"
     gene            complement(56100..57344)
                     /locus_tag="PK063_01610"
     CDS             complement(56100..57344)
                     /locus_tag="PK063_01610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00300 family protein"
                     /protein_id="HMZ95759.1"
                     /translation="MTALQETVFLQGHIIDSLILAKVLDTILMMGGTFDLQDVNIGAT
                     RDAPSQARIVVRAHSSRLLAEILQAIQPHGAAVERDTECRFEPAPAAGIFPDEFYATT
                     HLPTQIRLDGEWVEVEGMEMDLGICVDPAKARARTLPMGSVKAGDLIVTGREGIRVTP
                     LARPRERDVFGFMESVVSSERPHQPVIADIAQRMLKLRAGYRQGQTGTKVLLAGGPAI
                     VHAGGREALTWLIEAGFIHVLFCGNALAAHDMEAALYGTSLGYGLTAGRSVPHGHEHH
                     LRTINRIRAIGSIHEAVRSGVITEGIMAACVRQDVNMVMAGTIRDDGPLPGVVTDSMQ
                     AQGAMRAEVQGVGLALLVASTLHAIATGNLLPASVPTVCVDVNPSVPTKLADRGSFQA
                     VGLVMDAASFLKELARELGWRL"
     gene            complement(57445..58497)
                     /locus_tag="PK063_01615"
     CDS             complement(57445..58497)
                     /locus_tag="PK063_01615"
                     /inference="COORDINATES: protein motif:HMM:NF013322.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(13) synthase TruD"
                     /protein_id="HMZ95760.1"
                     /translation="MPTPSWLDDTVPYLTASVPALGGRIRSTPEDFCVDERPLYLPCG
                     EGEHLYIKITKRGLSTPDLVLRLSSHLHVKAQTIGVAGLKDAQAVTTQMLSLQGVKAE
                     AVAALPTDERLLSVEVLGRHRNRLRKGHHAGNQFRLVVRDVREGSEELLGRLFEELVR
                     RGVPNYFGPQRQGRSGTNFQLGAELLQDAARRNKMPRAKRIWFMNAYQSYVFNHIVAK
                     RIDSIDRVLLGDWAMKSDNGACFPVEQPEVEQLRADRFEISPTGPLFGSRAPWATGEP
                     GEIERAVIAELGTTPEVLSKAGAECGFRGERRALRVRLNDLVWSLEGSVLTLSFWLPP
                     GSYATSVLREIVKTNA"
     gene            58657..59283
                     /locus_tag="PK063_01620"
     CDS             58657..59283
                     /locus_tag="PK063_01620"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95761.1"
                     /translation="MFFFCACTVSQARSATAAARPIGIDVFAQLTQHIKRQADTDKEA
                     FAIASQCMNFFYKQQRHKPAPPAVQQIAWIPAESSELAAADSDAQEADCRKRYPEGLD
                     AVRTDFQRTQALLSLSLTFYEFALVGDGDDNSLYNARELHDILVALNLSAEPSLGAAA
                     HLRSLTAHFDSLHEARGMEALMAGMGKLYDQGYRVTTADKAHLNRVME"
     gene            59280..60113
                     /locus_tag="PK063_01625"
     CDS             59280..60113
                     /locus_tag="PK063_01625"
                     /inference="COORDINATES: protein motif:HMM:NF024258.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HMZ95762.1"
                     /translation="MISTVMRWQELARVWIGHWLSRPFHHLFNLIPGVEIGLSATVVT
                     RLPLTHAPLAGRRAVHLSDLHLDRYRPRHRALIRAVADLKPDWIFITGDLVNVRDGLP
                     HLLRFLTELRRLAPVYVTLGNHDHYSGIRVDEFAEQFDRRKVTLLLNQVTFIRVATGE
                     LAIVGLDDPSLHRADLRCMPSAQPGRFTLVLAHAPNILDQLRPEHHTDLTLCGHSHAG
                     QWQIPGIPTFWLPPGCHGRTHGMYEKGGHRLYVNRGLGWSVLPMRVNCTPEIVLLEWA
                     A"
     gene            complement(60149..60793)
                     /locus_tag="PK063_01630"
     CDS             complement(60149..60793)
                     /locus_tag="PK063_01630"
                     /inference="COORDINATES: protein motif:HMM:NF025030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HMZ95763.1"
                     /translation="MSPAMPRHSQSGQANLTAVFLLLGLVVSGVWVWKRLSPEMQDLI
                     IDQALPLAALVLAVLVFVWMLVGKIRARRTRNQQRARLIKLFESQTAADKRLQLAFAV
                     IEVNEYRRVGLEAIAPRFQELFLTTLKRALGDKQHQVRGMAASHLGVIGDETVVPHLL
                     KALEDDHAYVRSSAALGLGRLRATAAKDKLAYVSKEDWDQTVRSRAREALERIR"
     gene            60881..61339
                     /locus_tag="PK063_01635"
     CDS             60881..61339
                     /locus_tag="PK063_01635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HMZ95764.1"
                     /translation="MDLPDLKDDPHLKVLRPLVETYLAFWRADSRHVRSLRLTPSQFD
                     VIATLGDTKGLTCAELSTATLVTKGTLTGVLDRLEAKGLIRRTPVADDRRSTRICLTA
                     KGNKLFQTTFAAHIAFLRPFFQRALSAADADQLRTLLLRLHRSFQEKPVA"
     gene            61336..62094
                     /locus_tag="PK063_01640"
     CDS             61336..62094
                     /locus_tag="PK063_01640"
                     /inference="COORDINATES: protein motif:HMM:NF024118.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HMZ95765.1"
                     /translation="MIRLTVLGSGTNVHPTRAAAGYLLQTDQTFLLDFGPRTLSNLIK
                     SGVDRHSITHILFSHFHADHFADFIPFFFDAVIFCKYQGGTRPPLTLIGPHGTATLMR
                     SMMTTFPSFDRPPFRVTIREVADRSIRIGETRITPATVTHAPKLHCVGYRVEYQGHAV
                     AYSGDSQYCESLVRLCHEADFAVLDCSFPENRPGAGHLHAGLCGRVAQEAGVNQLVLS
                     HFYPIAEQYDVRAQAKHYFPGRVRIARDLLKLRS"
     gene            complement(62205..63065)
                     /locus_tag="PK063_01645"
     CDS             complement(62205..63065)
                     /locus_tag="PK063_01645"
                     /inference="COORDINATES: protein motif:HMM:NF024762.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase-like domain-containing protein"
                     /protein_id="HMZ95766.1"
                     /translation="MFVNESQIRALIRLLGDEDERIVKTISGKLIDFGDCAVPLLQEA
                     EIEQPEMADRIVTVLEEIRGARLEEELRDLIAFPDDQVDLETGAFILARYAYPTLDVQ
                     AYRRQLDRMAQDVREQIGSRVSGEETVRALNRYLFTEAGFKGNTKNYYEVENSYLNCV
                     MDRRTGIPISLSTVYLLIGRRLQLPVHGIGMPGHFLVKFDSDRYKIFIDCFNGGALLT
                     EKNCARFLTEAGYGFEDRFLQKSPTRAILARMIKNLLAIYNKLDEPLKKHRLPRFVEI
                     LGCEQREEGL"
     gene            complement(63092..63871)
                     /locus_tag="PK063_01650"
     CDS             complement(63092..63871)
                     /locus_tag="PK063_01650"
                     /inference="COORDINATES: protein motif:HMM:NF013245.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HMZ95767.1"
                     /translation="MKEYWQEIRALTMRWVRRLSREKFSMLFTLVQPMLFWLIFFGNL
                     FQRAADLQVTQSSSYISFLTAGVVVMTVLNNGLAGGVDLLFDKENGFLERLMSTPIHR
                     TSVILSRFIFVTTITSLQVLVILAVAWLFGVQPVTGLAGVATILLIGMMFGVGLTAIS
                     MAMAFSVKSHGDFFSVLGFLSLPMIFLSSALVPLAAMPGWMGFLAQFNPMTWAIDAVR
                     PLILQGWAEALPHVGMVIGVMVLFDALCLYGGAKAFRRAIG"
     gene            complement(63901..64872)
                     /locus_tag="PK063_01655"
     CDS             complement(63901..64872)
                     /locus_tag="PK063_01655"
                     /inference="COORDINATES: protein motif:HMM:TIGR01188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HMZ95768.1"
                     /translation="MSRPVAIDVSHLGKTYDKVRAVEDLSFQVYTGEIFGLLGPNGAG
                     KSTTLRILITLLNPTSGSAKIFGLDSVKDADRVRQTIGYVPQERAIDRFLTGREHLEL
                     LADLYHLSQEDAAGRIPQLLKLVELEQQADRPAKTYSGGMKRKLDIACGLLPDPKILF
                     LDEPTLGLDVQSRLRIWDHVRAMRERGITVVMTTNYLDEADQLCDRIAIIDGGRIKAL
                     GAPNELKVGLGGDLVSLTVREHDRVEKLAAAIRDLPAIRAVTVTANGLDIRVDSPEKA
                     LPAILEAANRLTCQLEFIDYHRPRLDDVFIAHTGRSIKDDHPKAEDA"
     gene            complement(64872..65561)
                     /locus_tag="PK063_01660"
     CDS             complement(64872..65561)
                     /locus_tag="PK063_01660"
                     /inference="COORDINATES: protein motif:HMM:NF014269.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LON peptidase substrate-binding
                     domain-containing protein"
                     /protein_id="HMZ95769.1"
                     /translation="MFPEPEREPSNRELSGKVQPFPVPERIPLFPLPNVVFFPKTYLP
                     LHVFEPRYRQMVADAAAAGQCIGMALLKEGWEEQYEGNPPIFSIGCVGRLASVQMLPD
                     GRSNILLQGLERYEIHEEFFEKSYREARVTLKPRDGSLSLDQALRRYLMGVLDEYLKA
                     DEEASPLHSLIRPDVSDEVFVNSLSTYLDCTPLEKQFLLEAEHVPQQARRLSDLIQFK
                     LAERRGAGGWG"
     gene            65741..66877
                     /locus_tag="PK063_01665"
     CDS             65741..66877
                     /locus_tag="PK063_01665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin-like domain-containing protein"
                     /protein_id="HMZ95770.1"
                     /translation="MTPLRLGCTIRLLLLAVLPVTAQAVATNETVHAFDMATPGYQYR
                     FPHDHGAHERFRTEWWYYTGHVVAADGHRFGFELTFFRRGMPPDQVQTLPSRWSIQQL
                     YLAHLALTDLDAGRFYYADKVSREGLGKAGADTDRLHVWVDRWSLLTNDPAASRHQLQ
                     AATDSVAINLTVIPKKPPVIHGHDGLSRKGADPGQASHYYSLTHLATEGQIRVGTETF
                     AVTGLSWMDHEFGSADLGLNVVGWDWFSLQLSDSTELMWYSLRRADGSSDPVSSGTLV
                     LADGRAHALDAQDLNIEPLAHWTSPRSNGRYPQRWRLTSATMGLDVTVESLLADQELD
                     TARSTGVTYWEGAVSVSGQVRGAPVTGRGYVEMTGYAERFTPKL"
     gene            66951..68000
                     /locus_tag="PK063_01670"
     CDS             66951..68000
                     /locus_tag="PK063_01670"
                     /inference="COORDINATES: protein motif:HMM:NF027232.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95771.1"
                     /translation="MSQRIRIATLLRRSICLLSFLLLACGSRESAVVSIALHPSNPNI
                     VYVATNDAVHKTRDGGATWEQFPAFTARRVTTLAIDPKLPATVYAGTMGDAIYKSPDG
                     GQHWLPHNVGLKEHVSFINEIIFHPDNTELIYLATTVGAFISKNGGREWEERMAGMKE
                     VHIVTCITMDHQHPRVLYAGTTGGTYRSEDGGTSWQKKNTGLIPEDVLNAAMALGVNM
                     LAVDPRNSEVVYAATTKGLFRSANRGESWEQIGQGLSNQFISTLALHPMDANIFYIGG
                     PDGVRKTTDGGKTWQSQNEGLTTTNIRTISLSPSDPQLLYLGTNGSGLYRSTDGGQHW
                     APIPLTGPQQPPPAS"
     gene            68021..68629
                     /locus_tag="PK063_01675"
     CDS             68021..68629
                     /locus_tag="PK063_01675"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: protein motif:HMM:NF012521.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HMZ95772.1"
                     /translation="MPTLLLIRHGETDWNRSGQVMGNQPIPLNETGEQQALACAEMLA
                     QTPIAGIVTSPVLRAVQTAHIVGRRHAAPVHHAPGLREIGVGNWINRYWKDLADDPAK
                     RDWYLHPDRARPSGGETLCEVQQRAVAAVEQALQVAQDGPYVFVSHGDVIRALLAHYL
                     RLDLNALRQARIDHAGVSGIEVTEAATHLLFLNHRPGLPRLA"
     gene            complement(68646..69125)
                     /locus_tag="PK063_01680"
     CDS             complement(68646..69125)
                     /locus_tag="PK063_01680"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95773.1"
                     /translation="MSVRSLCLLVGVLLTGLTGCSHHHGSYEHAKGDYYWGKASQDVS
                     GLVEKHVKNPETVKQVNVVMGEMIAEIKSAREQHRQFHRALYELNANYSAAPEEFTKI
                     LDELNNSRMRSSAKILGLRFKMKALLTAEEWTALSEELKRYGSRYYGKGAEGASAHQ"
     gene            69233..69589
                     /locus_tag="PK063_01685"
     CDS             69233..69589
                     /locus_tag="PK063_01685"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95774.1"
                     /translation="MGEQKAPQRGTGPVESLRDEFRQHLDVFYSRLKLAAPYDSVEKA
                     LGTLTTTLKALPPEELQRLGADQTQRWAHFRQAFVDSGLIQKHRGIIAGLARSSASPD
                     LPPEFNHLLDLYRPKT"
     gene            complement(69638..70267)
                     /locus_tag="PK063_01690"
     CDS             complement(69638..70267)
                     /locus_tag="PK063_01690"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95775.1"
                     /translation="MMLAGAFAIVLFIGLIVGDWMYFTRLSSDATRYGYGIGQVQDRF
                     AALTVPKLLRAFDTNGFLSLPHGVARVFPDANRMIIRPTHRLFSMRFRTAWPLKGSIE
                     LASDSDGLRMVCTKRVPWSSSILTFLWFSLVGFGTLGFLITYVLQGGLESLGSVLLGI
                     GVTGVGLIVVAFGLLTVTVAYRIENTRLMLVYTELRDIALANEGAASRP"
     gene            70524..71210
                     /locus_tag="PK063_01695"
     CDS             70524..71210
                     /locus_tag="PK063_01695"
                     /inference="COORDINATES: protein motif:HMM:NF024880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HMZ95776.1"
                     /translation="MDIAKVERVYTSYSGVYDHIFGKIFHESREACVRNLRIRPEENI
                     LEVGVGTGIALEYYPKNCNITGIDLSSGMLAKARQRQSHYHLDHVRLMLMDAGKMEFP
                     DDSFDTVMAAYVVTAVPDYRKVVNEMIRVCKPGGRIIMLNHFSNGNKVIAAVEKVISP
                     LCKHIGFRTDLSLNTVLEGTDLHVARKEKVNPMKFWHLVECVNRKGAKSSNGNGSVNG
                     NGNGRHGHVS"
     gene            complement(71271..72044)
                     /locus_tag="PK063_01700"
     CDS             complement(71271..72044)
                     /locus_tag="PK063_01700"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95777.1"
                     /translation="MTHSIKTADDVRWLLTHTQGFRGGRVMDVHLAKRWMLDEESGRD
                     VSAGRVVTVTVRYHLQGVLRIAKLSLHGVSDFSVFEQDGGDCAALGMIQVELHEGLLR
                     FWFDPQGNLYVVCEEALLEEVSVPHSDGDIHQGAAPWIFQADSGDPPTVDWLLTQLDQ
                     VGVPCIWKSTPRRAGHHGTLCWEGELVSTADVNAGPTAALTVRAYEPIDGAGFGIRLQ
                     PRLATGRFSGRLLRAVTEVVTQRYVGTCLTGERGVSSEW"
     gene            complement(72173..72376)
                     /locus_tag="PK063_01705"
     CDS             complement(72173..72376)
                     /locus_tag="PK063_01705"
                     /inference="COORDINATES: protein motif:HMM:NF016397.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95778.1"
                     /translation="MGSAFEDGQQAQLELAGLQRTLKWTNIQREQLLDRLDLLRLDNQ
                     RLQERVEELERQLAEAKQQQVLF"
     gene            complement(72525..73823)
                     /locus_tag="PK063_01710"
     CDS             complement(72525..73823)
                     /locus_tag="PK063_01710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ95779.1"
                     /translation="MSTVAIRAEGLSKHYRLGAAVQHNTLRDQLMHRLKSLTRWGSGR
                     SEPDPSFWAVKDVSFEVKQGEVLGIIGHNGAGKSTLLKILSRITQPTKGTVDIYGRVS
                     SLLEVGTGFHSELTGRENIFLNAAMLGMRRDEVRRKFDEIVAFSGVEDFIDTPVKRYS
                     SGMYVRLAFAVAAHLEPEILIVDEVLAVGDASFQQKCLGKMEEVSRSGRTVLIVSHNM
                     GIIEGLCERAILLENGRIARIGKTQTVVEGYADAIRSQASMSIGDRPDRVGLGEILLT
                     EIDLLDKDRHSVTSAITGRDVIIRMHYRCAEGKEFRNCRVSVSVNGRKGQDLFVLSTD
                     IVDPTPLTLRGTGYVDFILPDLPLTGGAYFLQSYIESNGHAQDWIKNVVPFPVLDADY
                     YGTGNLCPPGWEANGVLVRYRWESSDDLEGSTLPLRAREK"
     gene            complement(73824..74681)
                     /locus_tag="PK063_01715"
     CDS             complement(73824..74681)
                     /locus_tag="PK063_01715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HMZ95780.1"
                     /translation="MSVVNIDQRHPAVLPHVRIQPAKGLLELDLAALWQYRELIHILV
                     WRDVTVRYKQTLLGVAWAMFQPVATMLIFTVVFSVMGKIPSDGFPYPVFLYAGLLPWF
                     YISQALSRGGTSLVGEAPLISKVYFPRLILPLSATIAPLVDLFLAFIAFLGLMAWFEV
                     MPTWRILFLPLFAGLGAMITLAAGLWVSALYVRYRDVGHILPMFIQLGMFVSPILYPV
                     SKVPESWRAIYALNPVVSVVEGFRWALIPGFQVDFSMVLPSLGIVFVVFIGGLIYFRS
                     MERTFADVI"
     gene            complement(75028..75555)
                     /locus_tag="PK063_01720"
     CDS             complement(75028..75555)
                     /locus_tag="PK063_01720"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95781.1"
                     /translation="MIRRAIHLTAVLSLALSSACVSVQVDPLTTKAFEPRSGADAVTT
                     LQREPNHGHVQIARIVATSEYASEDTLRDRILERAKELGADAVVLGDADVRRLSDRGP
                     TFQSTMGTAVPGGVSNTNSYRSGYWNPFRMDAWSFTQGAGGGQGWMLHMSGLAIRYLS
                     AEEVRAAQKPPLSTP"
     gene            complement(75725..76081)
                     /locus_tag="PK063_01725"
     CDS             complement(75725..76081)
                     /locus_tag="PK063_01725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1499 domain-containing protein"
                     /protein_id="HMZ95782.1"
                     /translation="MKILAPCPSSPNCVSTQAADQSRQIAPYRYQQNLAGAQNTLKTI
                     INRLPRTRLVEENDGYLHYEFTSFLLRFIDDVEFVFDDATKMIQFRSASRTGYSDLGV
                     NRRRMEEIRTLVEGKL"
     gene            complement(76171..77373)
                     /locus_tag="PK063_01730"
     CDS             complement(76171..77373)
                     /locus_tag="PK063_01730"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013884.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HMZ95783.1"
                     /translation="MDATSLWPAAGVVLVALATAMFLPRTTLQEASSTPRYPSLDGLR
                     GYLALAVFVSHSSIWYFYLRSGTWDVPPSNVYTQLGQGSVTLFFMITGFLFWSKLLDG
                     RHQPIDWSRLYLSRALRLGPLYLVAVACVLLMSFGRTGFQMREAPAVVAEQTAQWLLF
                     TIPGISSVNGFAETVPLAGAVWSLPYEWLFYAGLPLAAFCLRTSPPIQWVIVSLAAVV
                     ILVMVMPQVRFPILYAFAGGIAAAGLVRIAAIRMMLSRGVWGAIAILCLATAFMAFPT
                     AYTVPATLLLAGGFLIIACGNSLYGILEWPASIVLGEMAYSLYLLHSVVLFVTYRLLL
                     AESAATLSPAEHWAMVLCQVPALILLCSATFRLVEKPGMEAVPRWHARLVARRADTSA
                     SAVPSGRR"
     gene            77635..78810
                     /locus_tag="PK063_01735"
     CDS             77635..78810
                     /locus_tag="PK063_01735"
                     /EC_number="2.6.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LL-diaminopimelate aminotransferase"
                     /protein_id="HMZ95784.1"
                     /translation="MAGFPIEVATRIKTLPPYLFAAIDKMKQEALARGVDIINLGIGD
                     PDLPTPAPIIESLYEAAKNPKHHQYPSYEGMLSFRKAVADWYKRRFNVTLDPANEVLT
                     LIGSKEGIGHVHLAFIDPGDIVLVPSPGYPVYPVGTSFCGGVSHIMPLTKANGFLPDL
                     NAIPKDVAKQAKLMWLNSPNNPTSVIMSKDYFKRVVEFAQENQIIVCHDAAYSEIFYD
                     GKRPASFLEVDGAKEVGVEFHSLSKTYNMTGWRIGFAVGNKEVLAGLGRVKSQLDSGV
                     FEAVQAAGITALGLDDSVTDGLRKIYQERRDTLVPGLKKLGLEVDAPPAAFYIWVTVP
                     KGYTSASFTAHLLEKAGIVTTPGNGFGAPGEGYIRMTVCTTKERLAEAVERIRKVGF"
     gene            78902..79465
                     /gene="folK"
                     /locus_tag="PK063_01740"
     CDS             78902..79465
                     /gene="folK"
                     /locus_tag="PK063_01740"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: protein motif:HMM:TIGR01498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HMZ95785.1"
                     /translation="MATAFIGFGSNLGNRIDFCDRAVTLLGLLPHSRLDAVSSLYETE
                     PIEDGAAPGPAWFLNGAVQVETNITPKSLLEICREIERALGRDQDNRKGPRTLDLDLL
                     LYDDCVLNDPGLIVPHPRLHQRRFVLAPLVELDPDRRHPVLGQTLRELLETLADPSIV
                     RRLDPQPNSRYGSRPACSPPPVQSPHT"
     gene            79429..80319
                     /gene="panC"
                     /locus_tag="PK063_01745"
     CDS             79429..80319
                     /gene="panC"
                     /locus_tag="PK063_01745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004592 - pantoate-beta-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HMZ95786.1"
                     /translation="MQSTPCAESSHVKIIRTTSAMANWSRGLHREGVTIGFVPTMGAL
                     HEGHRALVRAARLACDAVVVSIFVNPTQFGPTEDLAKYPRQFRLDRALCAKEGVDAIF
                     APTATAMYPAGFQSIVAVPSLARRWEGEARPHHFQGVATVVTKLLSLVQPDISWFGQK
                     DFQQAALVRQLAKDLNLSGTLRVHPTIREHDGLALSSRNVYLSASQRDAAPVLYRALQ
                     AGAAAIRSGERRGALIQRLMTQMIKTERSVTPEYLAVCDPSTLEPLPTIQRHAILLGA
                     IRLGTVRLLDNMPVAIRRKP"
     gene            complement(80401..80910)
                     /locus_tag="PK063_01750"
     CDS             complement(80401..80910)
                     /locus_tag="PK063_01750"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ95787.1"
                     /translation="MKELYCPACGTPCVRVTSGTSLIEKTLNRLSIFQVRCQLCTTRF
                     QARRPGNRLTTQAFDRREYRRLPVNFAGTLRLDHTAAGGVVTDISMGGCTLQATTPLP
                     RGTFVTFVLHGPSGQPDIKVEAAMICSIQPQSIGMKFLEFQPEDKQRMGQLVLELLAY
                     QQAPPRISV"
     gene            complement(80912..81340)
                     /locus_tag="PK063_01755"
     CDS             complement(80912..81340)
                     /locus_tag="PK063_01755"
                     /inference="COORDINATES: protein motif:HMM:NF013654.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG nucleotide pyrophosphohydrolase
                     domain-containing protein"
                     /protein_id="HMZ95788.1"
                     /translation="MMQPQDMVAEFHRKFDIPIGERPSIPPDATRQLRVRLIQEEFAE
                     LQEAMTAQDLPAVAKELADLLYVVYGTAVSYGVDMDPVFREVHRSNLSKVGGYKREDG
                     KWVKPPTYSPADVKPLLAKQLSGSVGSASHLETRSQESEA"
     gene            complement(81343..82752)
                     /gene="rmuC"
                     /locus_tag="PK063_01760"
     CDS             complement(81343..82752)
                     /gene="rmuC"
                     /locus_tag="PK063_01760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HMZ95789.1"
                     /translation="MIDLTSTTFIAGGVAGLGIGVLVTGWWVTARTQSRIQAQLLESG
                     ERAQRADALAVALQQRLDTQQSEVDQLRQALAESQEGRTKAETRMEVISRSMEDQKAM
                     LSQARQELQESFEALSGQALKQNNAAFLNLARASFETLHAEAKGELSQRHQAIGELVK
                     PLEESLHRYQEQLQQAEQIRQREYGGLDQQLKFMAESHQRLQQETSNLVKALRAPAVR
                     GRWGEMTLRRVAELAGMVAHCDFLEQDSVDSMDGLLRPDMVVYLPAGRQIVVDAKTVL
                     AAYLDAYEAQDDQQRQAHLRRHANQVRTRMDALSLKAYWNQFGQTPEFVVLFLPGEQF
                     LGAALEQDPSLIEDGFAQGIVLATPTTLMALLRAVAYGWRQEQLTEHAEQAGRLGKDL
                     YERMAVLTDHLNDIGQALGKSVGAYNKAVASLETRVLPAARKFKDLGISSEKDLAMLE
                     STGIEPRTGFPFAAEDMRT"
     gene            complement(82848..85478)
                     /locus_tag="PK063_01765"
     CDS             complement(82848..85478)
                     /locus_tag="PK063_01765"
                     /inference="COORDINATES: protein motif:HMM:NF013491.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PEP/pyruvate-binding domain-containing protein"
                     /protein_id="HMZ95790.1"
                     /translation="MIPSLILSLEESRDPSLVGGKAAGLSRLLAAGFAVPRGLCVPTT
                     VYRHVLAAGGVNAEEVWRRVLQGSQEERSQELARVHACLLKQAWPTGFQIALERRLVE
                     LTHDPTTRWAVRSSATNEDVEQASAAGLYSTSLGLSSSEILRGICDCWQSLWSDAAVQ
                     YALRTSSSKSFPSMAVVIQPLLQATTAGVAYSIHPVTGRTSQVVVNAVPGLAASLVSG
                     EVTPDQYVVEVAEDEGRPIRIRRRLLARKVQKLLSTPAGLHTESISEAGQKQSSLSDA
                     QLFELATLSKHIEAAFGHPIDLEWVWDADKVWVVQARPITAVQPSPALTNDECEWTRA
                     NLKETMPELPSPLGLSFLERFMDAYIVGPYRRLGCTVPEGLSSVRVMHGRPYLNVTLF
                     YTLVTQLHGNPSFLTEQMGGEPLGFTPSVRPLSGLALVRAGVLMMREWRRVVRQGPAN
                     FVAMKDMAQTYRPDRIRNLSAKELAATLDRLGQWLDTHEVTFGIAGGVAQSLQAMGTF
                     LPGWLGEDWRELLNASLQGQGSVISAQHILRLAELVEVASRESVVQRWFLREGWAASG
                     FREALAGTGFLRRFDEYLADYGHRAVGESDIMSPRIADQPDSVLMLLRTQLREGKAVP
                     PGDVMTQQAQRREAALAEIYRRFGWRRHRGVVFRWWYRRLSRFCALREANRHHLLYYS
                     TAVRHLLLQLGERMVEQGILTQPDDMFYLTMDERVALNEGASGDWQRLVRTRREQRTR
                     DQNASVPDTVRDWEAVLEQGPSMTGQVDGGLLRGIAVSAGTTSGPVRIVRSTQDWQRV
                     RPGDILVVPVIDPGMAPLFGIAAGLIAEMGGTLSHGAIIAREYGLPVLVNVPYATTLL
                     REDEPVHIVSSTGTISRLVP"
     gene            complement(85494..86834)
                     /locus_tag="PK063_01770"
     CDS             complement(85494..86834)
                     /locus_tag="PK063_01770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HMZ95791.1"
                     /translation="MIEIGVPQPRTRALLARLLQAGLHAVDPYEAVRRQVSIGRRHLT
                     IGSQQYSLNQVKRIVVVGAGKASARMAQALEHQLGPRIDAGLVVVKYGHGAPTNTIRI
                     VEAGHPIPDVAGLEAGRQVMAVVKTLTRDDLLIVLLSGGASSLLPAPVSGITLQDKQQ
                     TTKLLLRSGATIHEINAVRKHLSSVKGGQLAAATAARVASVILSDVIGNDLGTIGSGP
                     TAPDPTTFREAWEIVERYGVVKTIPASVRNRLSMGMRHRAPETPKPRASVFRRVDNIL
                     IGDNQAAVDAVATAAQQQGLRTLVLSTTLTGEARELAKMFGAMAREMARHGRPIPRPC
                     CIIAGGEPTVTIRGEGTGGRAQEFALAAAPEIAGLPNVWVAGFATDGTDGPTSVAGAV
                     VDGQTVVRARRKGLDLSQALQDNDAYPFFEKLHGHIVTGPTGTNVNDLYLLLAL"
     gene            complement(86840..87916)
                     /locus_tag="PK063_01775"
     CDS             complement(86840..87916)
                     /locus_tag="PK063_01775"
                     /inference="COORDINATES: protein motif:HMM:NF013618.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HMZ95792.1"
                     /translation="MRNNDWGLRAFVVGVTMVLGLAPLFAEVSLDSKAPAPSSPSASD
                     DSRVPIPERGTGPLSAEPEGAPELEDRLVILPEIKREGERFFLSSFKLPDKLTFAGQS
                     IPLDNWQVRERIEYEFYQFLEDQGESIILAKRTGRCFAPAEKQLADAGLPDDLKYMLL
                     VESKCIAAAYSRAKASGPWQFINSTGKRYKLHNERWLDERRNLEMSTEAAIKYLRYLR
                     ELQGDWFLAMASYNAGEDRVRKLLKEQNVTDFWRMHGPRETMRYVARIIAAKEIYSQP
                     EKYLGLTKKDLYPPLETETVTVTIKEAQRRLTSIAEEYGTYFLELKMLNPEFTKDYLP
                     KGSYQVKVPRQTCPNRCFKQDKLP"
     gene            88011..88718
                     /locus_tag="PK063_01780"
     CDS             88011..88718
                     /locus_tag="PK063_01780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HMZ95793.1"
                     /translation="MSTLSMLNADIIACTQCPRLVSYRESVAATKRRQYREWLYWGKP
                     IPGFGDPRARLYVLGLAPAAHGGNRTGRVFTGDRSGDWLYEALHRFGFANQATSTDVD
                     DGLALTDCYIGATVRCAPPANKPTPDEFTACRPFVLGELRLLEHVQVVVVLGKIAFDH
                     YFKACREMGRELPSPLPKFGHGVAYELAWGVSLIGSYHPSQQNTFTGKLTRPMFHRIF
                     SDAASRLEGNRRGSPSG"
     gene            complement(88725..89372)
                     /gene="fsa"
                     /locus_tag="PK063_01785"
     CDS             complement(88725..89372)
                     /gene="fsa"
                     /locus_tag="PK063_01785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HMZ95794.1"
                     /translation="MKLYLDTANVKEIQEGANLGLIDGVTTNPSLVAKEGRSFKEMLL
                     EICNMVDGPISAEVVGVESEAMIKEGRDLAKVHKNIVVKVPLIPEGLRATKKLSAEGI
                     RVNVTLCFSPTQALLAAKAGAWCVSPFIGRLDDVSSDGMALIRQIVTIYKNYDFKTQV
                     LVASVRHPQHVVEAALAGGHICTMPYSVFQQLVKHPLTDIGLKKFLADWDAMGKK"
     gene            89546..89848
                     /locus_tag="PK063_01790"
     CDS             89546..89848
                     /locus_tag="PK063_01790"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95795.1"
                     /translation="MRASVWLLAVGLLVGACSHNPYLDNSLTRYQGKDRAWIEKELGP
                     PDAKTTRFFGGEKWTYNRIAGGKAGPPLFNFKANECQMILFFDKDDTVSDSTYSGC"
     gene            complement(89845..90105)
                     /locus_tag="PK063_01795"
     CDS             complement(89845..90105)
                     /locus_tag="PK063_01795"
                     /inference="COORDINATES: protein motif:HMM:NF016811.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHS domain-containing protein"
                     /protein_id="HMZ95796.1"
                     /translation="MYRFFLIAVLLIVLYYLIRRAIRKIGQDGALEKPKDGRLSGNQM
                     VQDPVCRVFVARENAVKENIGGQTYFFCSRGCAAAFEKQLSG"
     gene            complement(90784..91587)
                     /gene="dapB"
                     /locus_tag="PK063_01800"
     CDS             complement(90784..91587)
                     /gene="dapB"
                     /locus_tag="PK063_01800"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HMZ95797.1"
                     /translation="MIKVVITGAAGRMGSRLVSLVKDSAFLTLAGAVESKGHHALGED
                     SGEVAGCGRTGVPIVEDLSSLMERGEVVVDFTTPAATLGHLRIVAQHRRGIVVGTTGF
                     SPSELDELRSVSKQIPCVFSPNMSVGVNVIYKVIAEMAKTLGEDYDIEVIEAHHRLKK
                     DAPSGTALKMAEVLARAVNRDLGQVGVYARKGLIGERKKGEIGIQTIRAGDIVGDHTV
                     MFGTMGERIELTHRASSRDTFARGALRAARWLVKQPPGLYDMLDVLSLK"
     gene            complement(91617..92489)
                     /gene="dapA"
                     /locus_tag="PK063_01805"
     CDS             complement(91617..92489)
                     /gene="dapA"
                     /locus_tag="PK063_01805"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HMZ95798.1"
                     /translation="MFTGSLVAIVTPFKNGKLDERALGDLIEWQINSGTHGIVPCGTT
                     GESATLTHAEHDRVVAFTVEVVRRRVPVVAGTGSNSTEEAIALTKHAKAAGVDGALLI
                     TPYYNKPTQEGLFLHYKAVAEAVELPLVVYNIPGRTGVNMMPSTIARLTVCPTVVAIK
                     EGSGAVQQASEIIQLCGERLTVLAGDDALTLPMMAVGGKGVITVTANLVPTKMAELVN
                     AFRDGRLEAARAMHYELYPLFTALFYETNPIPVKEALHLMGKIAPEIRLPLCPMGNDN
                     KAKLLTVLKAAGLV"
     gene            complement(92526..93788)
                     /gene="lysA"
                     /locus_tag="PK063_01810"
     CDS             complement(92526..93788)
                     /gene="lysA"
                     /locus_tag="PK063_01810"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HMZ95799.1"
                     /translation="MHDFQYRNGELYCEEVPLSRIAKEVGTPCYVYSHHTLVRHFRVY
                     DGAFKNIPHIVAFAMKANSNLAVLRLMAKEGSGVDIVSGGELFRALKAGVPASKIVFA
                     GVGKKQEEIRDALKADILMFNVESSAELQAINEVAASMDVKARVALRINPDIDPKTHP
                     YISTGLKKSKFGIAADRAIEEFKNAAAFSHIKVVGLHAHIGSQLTQVTPFVESLKKVL
                     TMVQTLAEQGIPLRYVNIGGGLGITYSDETPPEPKDLAEAISPLVRDLKCVLIMEPGR
                     VIVGNAGVMLTKVLYAKDGEAKRFLIVDAAMNDLIRPSLYDAYHDIRPVYEKVTQGEK
                     KTVDVVGPVCESGDFLAKDRVMPAMGAGELMAVMSAGAYGFVMSSNYNSRPRVPEVLV
                     HEGQYHVIRSRETYEDLVRGEHVPEFLS"
     gene            complement(93888..94190)
                     /locus_tag="PK063_01815"
     CDS             complement(93888..94190)
                     /locus_tag="PK063_01815"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95800.1"
                     /translation="MMSAGARRAAIQPHALLATVSFILLAGCGVLGAPIPPEDVGVAP
                     VVERQLRREGLLASGANVRGSASRPSAPSGLTIEETPIPPDPDPLPVSPWRTMGTR"
     gene            complement(94187..95641)
                     /gene="argH"
                     /locus_tag="PK063_01820"
     CDS             complement(94187..95641)
                     /gene="argH"
                     /locus_tag="PK063_01820"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004056 - argininosuccinate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HMZ95801.1"
                     /translation="MGKSTPVGARGRKSARAPQRSGRALPKGKAWGGRFAEQTDRLVE
                     QFSSSIAYDRRLYPYDIQGSIAHCKTLERAGVLTGRESGQLVRGLQFVKVELDGGRFP
                     FSPQDEDIHMAIERRLTELIGPVGGKLHTGRSRNDQVALDLRLFLRDVLSTFMKQVQE
                     FRRVLVGQARAHLDVVMPGYTHLQRAQPVLLAHHFLAYVEMLDRDRTRLHDCRQRLNV
                     MPLGSGALAGSNYPVDRRYTAALLEFPSVTQNSLDAVSDRDAVVEVLSTLSLIMMHLS
                     RLSEELILWASQEFRYVDLPDTFCTGSSMMPQKKNPDVPELVRGKTGRVYGHLMGTLT
                     LLKGLPLSYNRDLQEDKEALFDAVDTTGQSLVLCTELVRRLAVNRDVMAEAAEGGGML
                     ATELADYLVTTGVPFREAHSITGQIVRFSLEKRRPLQRLTLKELQGFSSHFKADVLNC
                     LTVRGAIDRKAQIGGTARRRVEARIKELEKALKG"
     gene            complement(95641..96858)
                     /locus_tag="PK063_01825"
     CDS             complement(95641..96858)
                     /locus_tag="PK063_01825"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HMZ95802.1"
                     /translation="MSQSSYKKVVLAYSGGLDTSVILKWLEEVYGCEVVAFCADLGQG
                     EDLKAIKKKAQSLGVKKVYVEDLRETFVKDHVFPMLRGNAIYEGSYLLGTSIARPLIA
                     KRQIEIAAKEGAAAVCHGATGKGNDQVRFELTYMALHPQIKIIAPWREWTMRSRRELI
                     EYAEKHGIPVTATKAKPYSMDMNLFHTSYEGGILEDPWEAPPEEIFVMSVSPERAPAK
                     AREVEIEYVAGNPVAVDGKKMSPAALLGHLNKLGGEHGVGRVDLVENRYVGMKSRGVY
                     ETPGGTILHAAHRGLESLTMDREVLHLRDSLIPRYAELIYYGYWYAPEREMLQVALDE
                     AQKDVTGTVRVKLYKGTCTVVGRKSPRSLYRLDMATFEEDDVYRQKDAEGFIRLNALR
                     LAIRAQRKKRPGR"
     gene            complement(96873..97853)
                     /gene="argF"
                     /locus_tag="PK063_01830"
     CDS             complement(96873..97853)
                     /gene="argF"
                     /locus_tag="PK063_01830"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HMZ95803.1"
                     /translation="MLRRLRRSTPRTGLGKDFLDLLSIPTDELTGLLRLAAQLKVKQR
                     RGVSHPLLQGRMLGLLFQKPSTRTRVSFEAGMNQLGGQAMVLPMGDIQLSRGESIADT
                     AHVLSRYLDAIVLRTFDHAIAEEWAREASIPVINGLTDLNHPCQALSDLLTIQEKKRR
                     LKGLKLAYVGDGNNVTNSLIEAAAKMGMTIAVGCPPGYQPDRRIVELSLAEAERTGAV
                     IEIGSDPSVAVKDADVVYTDVWISMGQEREQAKRLKTLAPYQLNARLLKCAKPDALVM
                     HCLPAHRGEEISAEVLDGPQSVVFDQAENRLHMQKAILVRLLGKKTARKT"
     gene            complement(97870..99075)
                     /locus_tag="PK063_01835"
     CDS             complement(97870..99075)
                     /locus_tag="PK063_01835"
                     /EC_number="2.6.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetylornithine transaminase"
                     /protein_id="HMZ95804.1"
                     /translation="MPTGELRLNAEQYLMNTYQRQPISIVRGRGSKVYDLEGREYIDF
                     VAGIAVNVLGHGHPDLVLAIQKQAQHLLHTSNLYYTEPQVRLAQTLVEHSFAQKVFFC
                     NSGAEANEAAIKLARKYSYDKYGADRHEIITMTSSFHGRTMATLTATGQDKVQKGFAP
                     LMPGFSYVPFNDLSALERAITPKTAAIMLEPIQAEGGVHVAERGYLQGLRELCRERDV
                     LLIFDEVQTGIGRTGTLFCYEQFGMQPDIMTLAKGLGGGVPIGACLATDSVARAFGPG
                     THASTFGGNPLACASALAVLRVLLDGKILDQGRRMGEYLAKGLATLKERHRCIKEVRG
                     MGLLQGMELDVDGKTVVADCLTRGLLINCVGERVLRFVPALIITEREIDRLLASLSQI
                     LSQRTTSTH"
     gene            99244..99885
                     /locus_tag="PK063_01840"
     CDS             99244..99885
                     /locus_tag="PK063_01840"
                     /inference="COORDINATES: protein motif:HMM:NF022400.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HMZ95805.1"
                     /translation="MKTCSQCRQENRDDARFCHQCGAPFALEARAAASETEQDAPQTD
                     TELLKAFIGPNADRYLETFKKFSGPGGPQFALSWHWPAFVFEPFLWFLYRKMYVYALI
                     YAIGPAMAFYITQDLSADIVWRVIAGGSANYIYFWHVKEQLAKIKSERATGGETREQL
                     LGELGGVQPYVVWVGVGLLVLKIGLVVAMFKEGPPDGPKGPPAKPHPASLTHV"
     gene            complement(99909..100742)
                     /locus_tag="PK063_01845"
     CDS             complement(99909..100742)
                     /locus_tag="PK063_01845"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95806.1"
                     /translation="MPDVSPSDWSSLQQWWQEMGRRLQVEDRVEAFFRRAMGASQALA
                     GAVQVGGEVEYILFVLVRYWIPVVLPPPGRERASKGDPDYWLESEQILKAAAVRLREL
                     KPLIELLTASNPLSAGVAEPQAARPPMVEVELANMLQGIAESAGSYGGPDYTSVIKTF
                     DPVPLRQTQPFKHNKKNSAELWVVFLLREHFRSLGLGKDRYWPLVAGLCAAAGIANPN
                     GQPYGPDELKSWWQKNWPRTYTQLEQTQAAPDLSGAAYQQDFDWFVSWIEWQRQQISE
                     V"
     gene            100933..101538
                     /locus_tag="PK063_01850"
     CDS             100933..101538
                     /locus_tag="PK063_01850"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HMZ95807.1"
                     /translation="MSKLVLIRHGESQWNLENRFTGWVDVPLSPKGIEEAKAAGKKLA
                     GFTFDRAFSSVLARANETLRFILEAIGQTTIPVEKDKALNERMYGELQGLNKAETAKK
                     FGDEQVKIWRRSYDVRPPGGESLKDTAERVLPYYESRIKPYVLKGETILIAAHGNSLR
                     ALVMQLEQLTREQVLELNIPTGAPLLYELDTNGKVQSHRYL"
     gene            complement(101585..102079)
                     /locus_tag="PK063_01855"
     CDS             complement(101585..102079)
                     /locus_tag="PK063_01855"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95808.1"
                     /translation="MKKESMTPAEAADALYKLMPRRITVEMLSDYGIQGEDAHEDAMT
                     RELLSFTLYWVLAAINAHIPRKYRDLVFHRVMDLIRADWETEYKLGALKWEEYLDEVE
                     ARRARYAPVGDYEGGAIAASEEISDLLETEGLIQPEDRPKLLVLLPDLVPLDKYQELL
                     SQCV"
     gene            102220..102771
                     /locus_tag="PK063_01860"
     CDS             102220..102771
                     /locus_tag="PK063_01860"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95809.1"
                     /translation="MTYARRIRLFLAGLAFIGFLSPCAAQSADPQEPHWGFATDLGLW
                     TGTTNNTTFALGFGLDYYMDPNFSFGGMALFTPVGDLTQIGVAGVAKYHLRLNSGFNL
                     VPFAGLGILHADLNRGSGPGKIDRNDTSHFIPLGMSLEYQVGPKIAFSTTLMVNLHHI
                     TLSPPVPNDNTSVALLFGIRWGP"
     gene            complement(103850..104872)
                     /locus_tag="PK063_01865"
     CDS             complement(103850..104872)
                     /locus_tag="PK063_01865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HMZ95810.1"
                     /translation="MRRMRVLVLMHKDLVPPEQLNGQDLDTAAWKTEYDVVSTLRKLG
                     HDVQALGVKSDLEVIRAAVEDWKPHIAFNLLEEFDGVAVYDQNVVSYLELMRIPYTGC
                     NPRGLMLARDKALAKQVMSYHRIPYPEFMVVPLHRMVRRPKYLPFPLIVKSITEEASL
                     GISQASIVDDDAKLRERVAFIHDNVGTGALVERYIEGRELYVGVMGNAHLQVFPVWEL
                     VMDKMPDESRRIATQRVKWSRKYQDKYGIRSCEARNLPDGVIDHIQHLAKRVYRALGL
                     SGYARIDMRMDQAGTVYVIEANPNPQIASGEDFADSAEKANLAYKDLLQELLHVGLRW
                     RPAQAA"
     gene            complement(104869..105930)
                     /locus_tag="PK063_01870"
     CDS             complement(104869..105930)
                     /locus_tag="PK063_01870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative zinc-binding metallopeptidase"
                     /protein_id="HMZ95811.1"
                     /translation="MGRTQIHRRQRSEPGGRVPVWAEWTDEQLLDLRMCDLDLRLDGT
                     FYQEPIEQLYRELDARRLVFRPHFWLSDEWFTPDGVPGIAVPFYLAHPRLAKLEASQM
                     LEVEGGTHDWCMRILRHEAGHAIENAFLLRRRRRRQKLFGRSSQPYPEYYTPRPYSRS
                     FVRHLDVWYAQSHPDEDFAETFAVWLDAGSLWKERYRGWPVLKKLDFMERLMGELAGV
                     APMVTGRQQLDPLPRIYKTLRDHYEEKRKHYGIGRASSYDTDLNKLFSAGVAYAKNPS
                     AAEFLRRTRKEIRRRVAEWTGEYQYTIDQVLEGMIERCHASKLHLTQQTEQAKLDFAI
                     LLTVQTMNYLHSGRHKVAL"
     gene            106209..107084
                     /gene="ttcA"
                     /locus_tag="PK063_01875"
     CDS             106209..107084
                     /gene="ttcA"
                     /locus_tag="PK063_01875"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HMZ95812.1"
                     /translation="MQPTSTKPVPAPARPAAQSEEIERVETRLCRLAGQAIADYRMIE
                     DGDKVMVCLSGGKDSYGLLEILLSLRSRAPIHFDIIAVNLDQKQPGFPAHVLPEYLTR
                     RGVPFHIETRDTYSVVKRLIPEGQTTCSLCSRLRRGHLYRLSTELGATKIALGHHRDD
                     ILETLLLNLFFTGKMKAMPPKLRSKSGRHVVIRPLAYVKEADLARYAALLQFPIIPCD
                     LCGSQEDLKRKQVKQMLQDWNQRFPGSNDSMFAALGNIAPSLLLDRSLFNFSDLKADA
                     ASPDASVSDAEEDLL"
     gene            107789..108226
                     /locus_tag="PK063_01880"
     CDS             107789..108226
                     /locus_tag="PK063_01880"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95813.1"
                     /translation="MNPVQQSPRQGAEPPLWSIAAAAAVILLTPMLLFSLAPDGPIRD
                     GDTVFSTGAHKVPLFKPEQHRQAGYDATCLLDPKDPMIVLHTPAEGSDEEDIIAQVQG
                     KNTIEWPFCPPQAELIIKPYHVTQQPSMIKDLRDGFLRLFKSS"
     gene            complement(108241..108786)
                     /gene="msrA"
                     /locus_tag="PK063_01885"
     CDS             complement(108241..108786)
                     /gene="msrA"
                     /locus_tag="PK063_01885"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HMZ95814.1"
                     /translation="MAQAGMEVATLAGGCFWCLEAVYDQVKGVQSVESGYIGGQIDEP
                     TYEQVCGGRTGHAEAVRVTFDPAVVSFRDLLEIFFVIHDPTTRNRQGNDVGTQYRSAI
                     FYHTPEQQQAAQEMIAAVTQEHLYPNPVVTEVVPATRWFEAESYHQEYFARNPLEGYC
                     TYVVGPKVAKFRQRFLALRKP"
     gene            complement(108819..110330)
                     /gene="zwf"
                     /locus_tag="PK063_01890"
     CDS             complement(108819..110330)
                     /gene="zwf"
                     /locus_tag="PK063_01890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HMZ95815.1"
                     /translation="MDLAQLRTPCVMIIFGIDGDLAKRKLLPALYNLMAGHFLPEQFA
                     IVGLDRSETTTEEFRAKLDRLMPEYLPENADRAVWQAVSQRVHYMAGDFQEGATYRRL
                     NDLLQGVDASAGTQGNYIFYMATIPGLFGRIVTHLGEYGLTVERDGTWRRVIIEKPFG
                     HDLDSAKALNHELQRVLQERQIYRIDHYLGKETVQNILVFRFANGIFEPLWNRRYIDH
                     VQITVAESLGVEHRGRYYEQAGAMRDMVPNHLLQLLCFLAMEPPNSFAADAVRDEKAK
                     VLRGVVPLSSLDVLRFVAFGQYGEGAVDGKPVVGYRAEPHVGAESTTETFVAMKLFID
                     NWRWAGVPFYLRTGKRMTRRLTEIVVQFKQAPFMLFRKTQVDRLAPNVLVIRIQPDEG
                     ICLRFDAKVPGPTVRIGEVNMDFQYADYFGNAPQTGYETLLHDAMAGDATLFQRADNI
                     ELGWSVVQMILDVWKSLPGSAAFPNYQSGTWGPPEAEALLRREGREWWNGGQA"
     gene            complement(110681..111001)
                     /locus_tag="PK063_01895"
     CDS             complement(110681..111001)
                     /locus_tag="PK063_01895"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ95816.1"
                     /translation="MERRDTPRYEIKVPLTFSGHAIDGSGLVTSLSKDGCHVTSEESL
                     PMRANLSLHVQFPAPYEPLTVEVAEVRWTNATGFGLVFVHVHDEEHARLQRFIDWLKR
                     TQNN"
     gene            111351..111713
                     /locus_tag="PK063_01900"
     CDS             111351..111713
                     /locus_tag="PK063_01900"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ95817.1"
                     /translation="MDTDLRSSTRVTVTYPVRLSGDSMIGQGTVVNLSAPGCAIETTL
                     PVRPGDYLELHVMAPDQARPLNVGLAKVRWATEQKAGVEFIRVRRDEQSRLQRLIGQV
                     LEESAIGSERDRQELTAA"
     gene            complement(111805..113196)
                     /locus_tag="PK063_01905"
     CDS             complement(111805..113196)
                     /locus_tag="PK063_01905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3422 family protein"
                     /protein_id="HMZ95818.1"
                     /translation="MTDTVESTGTHSRPPGFLNRIHQSNKQYLPQWLGVPAHIHHVAY
                     RMANPPVERPNSRREFQHLLQALEISEGAIEERFGYGFKTAPNGDRLVVVWEAHTEYY
                     SYQVWHVVGDSNTPLDFGPITFPGYQMPLCPLGLRVNALDLLFLPQELPLDRELPARL
                     PGAMVYGSRILGDDIVAVTSFTPDEFDRERYLICSTSEQALRQQVAKIVDTIVAIENY
                     YHLVMLPMKAFSRAVDQIHDYEQRHLYQRAVLIEQLGGTNPPTMQKWLTVLTQDLLQV
                     SRLAESMRYRLSASVPYDRIVQSNLVALQERPYPPLRQISEYVSWKITGVTDGYQQLL
                     RRIDAMEKDFEATVAVLRTHIELRLQEQNIQLQDQNMKLLASVDSTTRAQAILQRTVE
                     SLSVIVITYYLTGLGSYVLKACYEMGWVKNANVATAIFVPIAFAISFTLMTVGRKIII
                     KRMANPAGDPGGH"
     gene            complement(113320..113484)
                     /locus_tag="PK063_01910"
     CDS             complement(113320..113484)
                     /locus_tag="PK063_01910"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95819.1"
                     /translation="MNQRFGITVKFLISADSPEEAEEIIESACEKMASSIHEGDVSYE
                     GIEDIEEEDE"
     gene            complement(113801..114544)
                     /locus_tag="PK063_01915"
     CDS             complement(113801..114544)
                     /locus_tag="PK063_01915"
                     /inference="COORDINATES: protein motif:HMM:NF012894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HMZ95820.1"
                     /translation="MKYRGASQLMLGGMAMVLLTAPGCSGMKWFQSGSDESSNSGSSL
                     SASSGASGGYGRGEAGRDGQYPSLGRQDGSSQQNDASDTEGGKLRGFSPLVNGQIAGE
                     ERLSRSPIGSMLTSNEQDAKWAAEIRREEAAALEAGLQDVFYGYDRYNVSDNDGVASL
                     TVNAGWLKENPKALLKISGHCDERGTHDYNLVLGEKRAKAARSFLIDMGVSAKQVAIV
                     SYGKDRPFCADHDEVCYQQNRRGHMLLRK"
BASE COUNT        24868 a        35278 c        31316 g        23471 t
ORIGIN      
        1 ccttgtactt caaatgccca taccaggcga aggtcatgaa gatgttggaa atggtcagta
       61 agagaatcgt gtgcatgggc ctccttgttc atctatgatt cagggagatc ctacagcaga
      121 agctcgctct gcatcgctta gcgtgacagc gagcccatcg aaatttctag ttcgccgaaa
      181 tcataaaccc tcgcgcagga ttctccgttc tttcgttcca ctccatgata tagctttcga
      241 acaatatctt tctcgataaa cgtcattcca tagtcggcag aatcgatctt cagtgcaatt
      301 atctttggat ggtcgagaca gtcaggtcca aaggtatagg acgggcgcaa aaaatcctgc
      361 acctcgctat tcgtccaagg ggtcagagcc gcaataacta ccccaagggg aaccacaatc
      421 caccctatgg gagcgacata aacgacaccg acaatcccat gggtttctat tacaaatttc
      481 ccatcgtttt gtgtgtgtgc taccttgccc acatttctga catgaatgga ttctacggga
      541 gacaactgta tccgaacttc ccgcccatct aaaggttggc cctcttcgtt gctcactttt
      601 ccttcgaacc gaagataccc cgttccctca ccaacataac agccgttgag aagaccgaga
      661 aatcccacaa tcaggattcg gatgagtaag ggcattttca ctcgcctcag gggaaattga
      721 tccgatggtg cccttttgct cgatcacctg cgcgggcgga ctgcgccgac cctccactgc
      781 gggcggccaa cctcttcctt tcttgcgggg gtggaagggt ggagccttca gagtgcggta
      841 tggcgggcgt ggagagatgt accggataac ctgtcacagt gcggcgtctt gcaacccttt
      901 tgtcgcgcat tagagtggca cgcggctgga accaacgcat gactgtggac tctcatggac
      961 tgtccgtctc ttctcctacc tcttttttcc taatcacccg ctccccttct ctcttagcgg
     1021 ggtgtaaggg atggagcctt tggaagtcgg catggcgggt gtggaaagat gtagcggata
     1081 aacctgccgt tgtgcgacgg catgcgactt tcggtcgcgc ctcacagtcg cacacggcac
     1141 cggagcggat cggaagcaac ttcgatcctt cgcatcatgc cgactccgaa gactccatcc
     1201 cttacacccc cgcctctctt aacacctgtc ccgtatacga ccgcttcacc ttagcgattt
     1261 ctttcggcgg gccttccgcg acgatttcgc caccgcggtc gccgccttct ggcccgagat
     1321 cgatgatcca atcggcattg cggatcatat cgagattgtg ttcgatcacc agaacggtat
     1381 tcccagtctc aaccagacga tcgagcacgt ccagcaatcg ttgaatgtcg gcgaagtgaa
     1441 ggccggtggt gggttcatcg agaatgtaca tggtgcggcc ggtggggcgt ttggaaagtt
     1501 cgcgcgagag cttcacccgc tgagcttcgc cgcccgataa ggtggtggcc gactgcccca
     1561 gcttgacgta gtgcaagccc acgtcgtgaa gcgtctgaag tttcgacttg ataaagggga
     1621 tattttcaaa aaactccaag gcgtcatcca cggtcatgtt gaggacgtcg gcgatgctgc
     1681 ggcctttgta ttgaatgtcc aaggtctcgc ggttgtagcg ctgtcccttg cagacctcgc
     1741 aggtgacgta gacgtcaggc aggaaatgca tttcgatttt gatcagccca tcgccctggc
     1801 aggcttcaca tcgtccgcct ttgacattga agctatagcg gccgggcttg tagccacgca
     1861 cgcgagactc aggcaaattg gaaaacagat cgcggatgaa cgtgaagagt cctgtgtacg
     1921 tggcagggtt cgaccggggc gtgcgcccga tcggggattg atcgatgtcg atgattttat
     1981 ccagcgcgtc cacgcccttg atctctttgc agccgtcgat tttgggcttc ttgtgataaa
     2041 gcagctgcga cagcgagtgg aataacactt cgagcacgag ggtgcttttc cccgaccccg
     2101 acacacccgt cacgcaggtc aggaggccga gcggcacatt gacgttcacg ccttttaaat
     2161 tatgtttctt cgcgccgacg acggtgacga acccttttgg ggtgcggcga cgctggggaa
     2221 gcgacaccat ttgcgcgccg cgcaggtaga ggccggttaa cgaatcgggg ttcgccttga
     2281 cctgtttcgg agtcccctgg gcgatgattc ggccgccgtg ggtgccggcg cctgggccca
     2341 ggtcgagaat atagtccgca gcctccatcg tctccgcgtc gtgctcgacg acgatcaccg
     2401 tgttacccag gtcgcgcagg cggagtaagg tctgaagcaa tcgccggttg tcccgttgat
     2461 gcagtccgat cgacggttcg tccagaatgt acaacacacc gaccagaccg gacccgatct
     2521 gcgtggccaa tcgaatacgc tgcccctccc cgcccgagag cgtcgccgcc ggacgatcca
     2581 acgtcaggta gtccaatccg acattgacca gaaacccaag ccgctcgcgg atttccttca
     2641 ggatgcgatg ggcgatgacc aattcacgtt cggtgaattt gagcgtggcg aaaaaatccg
     2701 ccgcggcacg cacggagaga ccggtgatct cggcaataga cttcttggcg attcttaccg
     2761 ccaggctttc cggcttgaga cgcgcgccct gacaggtctc gcaccgttca agtagggtga
     2821 agtcgtcttc ttccgtggca ccgggagtca tggcataccc gatcccgtcg caggccgggc
     2881 aggcgccgtg ggggctgttg aacgaaaata cccgcggcgt gatctcagga taactgactc
     2941 cgcatttgat acaggcgagc ttgtcgctat agaggtgcag cttgccggtc tccgacagaa
     3001 ccccgaccaa tcctccggcc agcttcaccg acgtttcgac ggaatccgcg atccgccgca
     3061 tcaaggcatc gcccggcttc atcaccaacc gatcgaccac gatttcgatg gtgtgcttct
     3121 tctgcttgtc gagggtgatg tcctcgccca gatcgaccat ctcgccgttg atcctggcgc
     3181 gcacatatcc ggctttgcgc atctccagca gttctttgcg gtattcccct ttccgacccc
     3241 ggactatggg ggagagaatc tgaaactttg acccctccgg cagttcgcag atggcatcca
     3301 ccatctgctg taccgtctgc gcggtaattt cctgtccgca ttggaaacag aacgggtgac
     3361 cgacacgggc atacagcaga cgcagatagt cgtagatttc ggtgacggtt ccgacggtgg
     3421 accggggatt gtggctggtg ctcttctgtt cgatcgagat tgccggcgac aacccttcga
     3481 tggagtccac atcgggcttc cccatctgtt cgagaaactg ccgggcatag gcggacaacg
     3541 actcgacata ccgccgctgc ccttccgcat agattgtgtc gaaggccagg gaagatttcc
     3601 ccgacccgct caggccggtc atcacgacca gcttgtcccg tggaatctcg acatcgagat
     3661 tcttcaggtt atgttcacgc gcccctttga tgatgatgga attgctcata agcgcgggat
     3721 tatatcacgc cgggcaacga ggcttggcat ccgacacctt aaacttgacg ctcatgctca
     3781 gacgaccgtc aaaatgtcga cgcggtgttc cagcatcgaa cgatggcatt ttagttttcc
     3841 acgaatgtgc cgatacggaa ctgcgggaac cttcgccccg atccacaacc accccgattt
     3901 cgatggccgc catgcatgac gtgctgagcc tcttcaaacg caacatcaat caactgttcg
     3961 ggatcaccgt cgatatcctc aacgtgggcc gctctctcca acaactgtcg ctctccatgc
     4021 aaattctcgc gaataatggc gtggtgcaag cggccaaaat ccctgggggc aaaggccggc
     4081 ccatgctggc gctggttgag atcttgaata acacccctaa ggaaatccgg ccggaagtgg
     4141 aagccctgga gcatctctgt gccgggctgg ccaaggtgac cgccagcagt tcaaacattg
     4201 tctggcgata ccatcaattg attgccagtc tgctttcggc gatgacacag ggggagctct
     4261 cttccaagtc gaagagcttg gagaccctct cgcaccttcg ctttaccact gccgccgacg
     4321 taacccaatt gacgcaacat cccgccttca cagcggtggg gggcctggag cgggagaacc
     4381 gcttgtatct ggtgcatcat tgccaggcga acctcactga gttacaggaa cggctgaagg
     4441 aggcgctgcg gtgtctgggg gaaacgcatc aggcgctgaa cgggctgaaa atgattggac
     4501 tcaccgcgcg ctatatggcg ttctgcatct cttctgaggc ggcggggctg gcggaggcgg
     4561 aggccaactt caaaaatctg gcagccgaaa tcagccgggt cgtcgacgac ctcgataaca
     4621 agacccgcgc gatgaaggat gccatcgaac atgggcaaga gctccttgga ctgctgctga
     4681 aagggcatac ctatgcaaag taaggtgttg ttcaataaag acgatcatca gtgggtcgtc
     4741 atcggccgtg accccgaaaa ggatgaccac gtcatcgaca ccaacgaata tgtgatcatc
     4801 catcgcggcc atgccatgct gctggaccca ggaggcattc agattttccc ccaggttctg
     4861 gccgaattag cgaagtatgt ccgcatgcag gatatcaagg tgatctttgc cagccaccag
     4921 gacccggaca tctgctcctc gctcgccatg tggctcgacc tgaatccggc gatcaagacc
     4981 tattgctcct ggctctggac cggctttgtc agccatttca gcaccggcgc cgtcatcaca
     5041 ttaaacccga ttcccgacga cggcatgcgc atcaagatcg gcgaggaagg tcctgaaatg
     5101 gaagccgttc cagcccatta ttgccactcc tccggcaact tctctctcta cgaccccagt
     5161 gcaggcatct tgttctcggg cgacatcggc ggcgcccttg tcccggacca ccatgccagc
     5221 ctgcttgtga cggatttcga gcagcacatc cagtacatgc gggggttcca tctccgctgg
     5281 atgccctcta ccacggcgct ccgtggatgg gtccaacggg tgcgtgccat caagcccaag
     5341 atgatctgcc cacagcatgg atcgattttc gaaggagaga acgtcggcaa actgctcgat
     5401 tggctggaaa gcctggaagt cggccagtgg aaagggtcgg ccccgaagag cgagacccgc
     5461 gccgccgcct aacgccggca ccccggcgag ccaatcgatt tcgatctccg tccgcacaga
     5521 cccgcgacct tgacaacggg caaaagcggg tgctaccacc ctcccatggt gcgggcagaa
     5581 caatctccga taaccgaacc ggcggcgaaa gccgtctcaa cctggtccgg ccaggctcgt
     5641 gaacaggccg tccagcgcat gttcaccgcg atcgcgggcg tctacgacct caacaacacc
     5701 ctgctcagct tcggtctcca tcaccattgg aagcgcctca cggcttcgta tgtgccgacc
     5761 gtaacgaacg gccgtgcact cgacatcggc gccggaacgg cggatctcgc cctgctgatc
     5821 gaaccgaaaa tgggcgaacg gggccatgtg gtggcctccg atttaaatca tgccatgtta
     5881 gccgaagggc tccgcaaagt gtcggggaga gggctcctcg atcgcattac ctgcctgcag
     5941 gccaatgcgg aacagctggg ctttcccgat aatacgttcc atgcagtgac gaccggcttc
     6001 tgcatgcgca atgtgggtaa cctgacccag gcgttcacgg aaatccggcg ggttcttcga
     6061 cctggcggcc gtttcgtgtg tctggagttt tcccggccgg cctatggctg gttacgtgcg
     6121 ctctatgatt ggtattcgtt tcgcctgctc ccgtggatcg gcaccagggt ggcgcgtgat
     6181 cggaccggcg tctatgaata cctgccggcc tcgatcagga ctttccccga tcaagagcga
     6241 ttggccacac tgctgaggga ggctggtttc cgcgaagtgg aataccggaa cctcaccgga
     6301 ggcatcgtcg ccatccacgt agcaaccaaa taataaccac gcgatcagct ttcggctctc
     6361 agcacaggct gatggctacg agctgacggc tgacagctga tgaattccat cctctacatt
     6421 tttctcccct gcaaaaaggt ctacccgatc ggcgtgacct acctggcaga ctttatccat
     6481 cgccggaaac ccgaggtgcg acagcgcatt ctcgatctgt cgctgttttc cgaatcccaa
     6541 cggacgcaag ccatccgcga tgccgcgctg gagttcaagc cggatctggt ctgtttttcg
     6601 tggcgggaca ttcagatttt ctccccccac gaaggagacg cctcgctgga gcacgccttc
     6661 aatttttact tcgccagcaa tccgatcaag cgggtggccg cgtcattcgc cggcttgaag
     6721 cagctctacc ggtattacag ccacattcgc gcgaacctgt cgtatccctg gttgatccgg
     6781 aaggaatttc ccaagaccca gatcatgatc ggcggcggag cgttcacggc gtttgccgat
     6841 caattgatcg agaagctccc ggaagggact attggaatcc tcggcgaggg ggaagacgca
     6901 atcctcaagg tggtcaacgg cgaatcgctt gaaaacgaac gctatatcat tcgggaaggg
     6961 aaacagacgc gtaagggaaa tcagggctcc ccggccctgc tggacgcatt gaccgtcgat
     7021 ctgccctacc tcacgtctat ttttccccag cacgcctcgt acatggacga atcgatcggc
     7081 gtccagacga aacgcggctg cccctatgat tgtgctttct gcctctatcc ctacatcgag
     7141 gggaaacggg tgcggtatcg gccgccagaa atggtcgtca aagatatctc tcagcactat
     7201 catcagtggg gcgcccgtcg attctggttc accgatgccc agttcatcac gggcaaggaa
     7261 gcctatcctc aatgcacaga gattcttgaa cgaatcctga gcgaaaagct ggagattgag
     7321 tggtcgggct atattcgcac ctcgctgatc actccggagc tggctaagct gatggtgcga
     7381 tcgggcgtcg gagacttgga agtcgccatt acctccggat cgcaggaggt gctcaacaat
     7441 ctccatatgg gcttcaaact cgaacgtctc tatgacggat gccggtatct ggccgaagcc
     7501 ggtttcaaag ggaaagtgat cctgaattac tcgctgaact ctccgaagga gacggaagaa
     7561 agtctgcttc aaagcgtgga gtcctacaaa aaagttgcgt caattttagg tgaagagcgt
     7621 gtgttcccgc tgatgttctt cctcggtatc cagcccaata cggatctgga acaccggctg
     7681 ctggaagaag gctacctttc agccggatat aaccccctca tgttgacgcc gaccagcatt
     7741 cgtaaactgc tttacaaccc ggccccgctc aacaaaatca tcgccaaagc ttgcctgacc
     7801 gcctgggaac agaaagaggg cagccgcgat cctcgcacat ggaccggatc cctttctcaa
     7861 acaccccccg ccggagcgaa gccggaccag gctcattatg ccgatgcgaa tctcattcgg
     7921 gggattcaga ataactcggg acgtgaagcg ctcttgacgt tggaagagat ccttcgatca
     7981 cgccgccccg cgcaaccaac agccgccgca acggaaaaga cggctgtgag tccaacgagt
     8041 tagcgactat ccacagaccc tttgaccacc gtcggtttgc ttgcaatccc cgagaacacg
     8101 gtgctatcat gccgcttctt ttggggtaaa gttccattca accgtttgaa ttcttggcgg
     8161 ttctctgatc tcatccccct atagagtgtt tgcctaggag gcgtttcgat gtacaagacg
     8221 atctatatcc cggtcgataa ttccgaccat tccaatacag ccgtcgatgt cggagttgag
     8281 ctggcgaaaa cctatggctc aaagatcgtg ggtagccatg tctacgcggc gaagatgcac
     8341 gataagcgat ttaagcagat ggaggctggc cttccggaag aatatcacga cgagaaagaa
     8401 ctcgaccggc agcgccaaat ccatgactcg ctgatcaccc gcggactgca gatcatcacg
     8461 gattcgtacc tcgattacgt cgacaagaaa tgtaatgagg ccaacctgcc ggtggaacgt
     8521 cgctcactcg aaggacgcaa ctggaaagtg ctggctgagg atatcaatac gaacgcctac
     8581 gatctcgtga tcatgggcgc gttgggagtc ggagccgtca aagacagcgt catcggcagt
     8641 aataccgagc gagtcctgcg gcgcgtgcgc aactccgaca tgctgatcat caagcagccg
     8701 acgcctgttg gcacggggaa aatcgtcgtc gctgtcgacg gcagccccta ctccttcggc
     8761 ggactcatga ccggtttggc acttggcaaa gccttcaatg tcccggttga agtcatttcc
     8821 gctttcgatc cctacttcca ttatgcggcc tttcacagca tctccggcgt gctcaatgaa
     8881 gaagccggca aggtgttccg cttcaaagag caggaaaagt tgcacgagga agtcatcgac
     8941 agtggtctgg caaagatcta ccaatcgcac ctcgatattt cccgcgaaat tgcccaagcc
     9001 gaacagaccg atgtgaaaac gaccctgctg gacggcaagg ccttcgaaaa aatcattcaa
     9061 tacgtgcgga aagagaatcc ctggctgctc atcgtgggcc gaatcggcgt ccacagcgat
     9121 gaagacatgg acatcggcag caacacggaa aacctgctcc gctctgcctc ctgcaatatc
     9181 ctggtttcca accggaaata cgtcccgccg atcgatacac aggcggaata caccattgcc
     9241 tggacggaag aggccttgcg tcggatggaa cgcatcccgg tgtttgctcg cggagtagcc
     9301 aaaaccgcca ttcaccgcta cgccattgag aagggacaca cgatcatcag caatacggtc
     9361 gtggattccg ccgtcggaca tatccttccg aagggcgcga tggacgccat gcgtgcgttg
     9421 ggcgggaacc tggatgcggc cggcattgat cgcgacaaga tgcaagccga cgattccgtt
     9481 gcgcaggatc tgatgggctc gacgctgagc ggcatgatga cgcaggtcgt ggaagaaaag
     9541 ccggcccata gccctggaac tcaggcgtat ctggatcgca tgagccagaa ttactttgtc
     9601 tgtgacggct gcggatatat cggcaaaggc gatacccccg tgaaatgccc cgtgtgcagc
     9661 gccgaagggg atcgattcaa gcaggtcgac aagtcgatct tcgaagcggc cgctaaagcg
     9721 gagggcggcc tcgagaccga cgtcgcctat gacgacattc cgatgcagtg gacgaaggac
     9781 gcgaaggaag cgatccgcgc agtaccggcg ggattccaac gccgccgggc taaagccaag
     9841 atcgagaaaa gcgcccgcaa gctcggcatg acgacgatca ccctcgaata cgctaatccc
     9901 atgattcaag aagcggcgtc cgaggactac accccgatct ttgcgaacaa gggcaccgga
     9961 accgcaggcc aaccttcggc ggaagtaccg accgccaatg gcactgaatc cgctacggcg
    10021 aacggcaacg gaactgaaca acctcaggct tctcaagcac catcttcgcc ttacacctgg
    10081 accccggatg cgcaaggccg tttagatcgg gcccctgaag gattcatgcg ggaatgcacc
    10141 aaggcgttga tcgagaaaca tgctgacaag atcggcacga cggtcatcac cctggaagtg
    10201 gcaaccgagg gaattgagca agccaagggc tatatggccg atgccatgaa aaccggcaat
    10261 ctgaaggaca tgattgccaa cctgacgggc tcgtccaaga ccggggcgaa ccggtgatgg
    10321 gaaagtcgtt gccggttctc aatattccct ttctcggaga caagctggag tcacttcagc
    10381 aacagatctc gaagttcatc tctccgactt caccgggcac agcgccgaat gatggccgga
    10441 cggtcgatga cttcaagccg tatctcgtcg ccctgaacct caccaagcga tgcaatctca
    10501 agtgcgacca ttgctatctg gacgccacga cgaaagccgg cggcggatcg gatgaactca
    10561 gcacggaaga atgcttccgc ctcatcgatc agattgccga agtaaataag ggatgcctgc
    10621 tggtcatcac cggcggtgaa ccgcttgtcc gtccggatat tctcgacatt gcccgccacg
    10681 cagtagggct gggctttatc gttgtgttcg ggaccaacgg gatgctgatc aatgatcgca
    10741 tggccaagac gctggttgaa atcggcgtga tgggcgtggg catcagcatt gattcgctca
    10801 atcctgagaa acacgaccac tttcgcggag tgcccggcgc ctttgccagt gcattggccg
    10861 gcattgaagc ctgcaagcgt aatggccttc agttccaggt gcatttcagt gcccagccca
    10921 tgaattatca ggagctgccc gcggtagtcg aatgggccca taccctgggc gcacgagtcc
    10981 tgaacgtctt tttcatggtc tgcaccggac gcggcgaaga gctgaccgat atcacgccac
    11041 agcagtatga agaagtgctg ggatatctgg tggactgcca ggaccaatat aaagacatgc
    11101 tggttcgggc acgttgcgct ccgcatttca aacggctggc ttacgagaaa gatcccaatt
    11161 ccccgctaac caaggccacc gggtacatgg gcggaggttg ccttgccggt accaactatg
    11221 cccgtgtcac gccaaacgga gaactgaccc cctgtcctta tatgccgctg tcggccggca
    11281 atgttcggga gacgagtttt gccgatttgt gggaacggtc ggatgtgttt aactccttcc
    11341 gctaccctca actcaaaggc aaatgcggtg actgcgaata caccgacatc tgtggtggtt
    11401 gtcgggctcg tccttacgtg gatcatggcg actggctgga tgaggatcag tggtgcctct
    11461 atacaccgaa aggcggcgac aagatcaaag tcgccttcaa cacacctgaa gaaagcgaag
    11521 ttgcatggga cgaagcctct gagcttcggc tcagccggat tccctatttt ctccgcgcga
    11581 tggtgaaaaa gggcgtcgaa cgtcatgctc gtgaaaacgg catcgccctc gtgaccatcg
    11641 aattgatgga agagctgcgg aagaagcgtt tcggcaacga tgcgcctgtc ttcaatttcg
    11701 atatgagagg gaaggactag gagccggcgc gagacaggcc ttcggtagac tcccctacct
    11761 ttgctatccg ccctagccca tctatcatgg attccgtaca aagcatcttc cttgacctga
    11821 accagctcat ccccatcgtg aatcactggt tccatctcct ctcggcggtg atctggatcg
    11881 gtggactcgc cttcattgtg atggccgtca agccgggcct cgctgaagcc gccctaccca
    11941 aggaatatgt ccgccccatc accgatgcct tttacaagca ttacaagcgg gtggccggag
    12001 tcctgttggt ggtcctcctg tttaccggcg gcatcaacct ccactacgtc aaccagatct
    12061 ttgtgtctca gaccggtcag ggcatgcagc accatcccaa gtatctctgg attttctgca
    12121 ttaagctgat tctggtcctc tgcctcctca cgctgttcct ctataccgtg atcttcaaaa
    12181 cggatcagga cgaagaagag gaaggcgaaa actacgagtc gattcccttt caacgcgccg
    12241 ccctctggat gggcttcttc atcatcctct gcgccgccgc catgaagcac ctgcaccaat
    12301 agtcctttcc tcgaccctcc ggacaacgaa tctcgaccgt cggcatgctg cccggccgcc
    12361 gggccggaat agtctcaaag gttcatacct cataactcga ctttcaaaat ctattggcaa
    12421 tcagagggcg atccaggtac ccttcgtccg cgcctatggc atgtgagttg ctttctgcta
    12481 cggagagggc cgcgagtttc atcgctccac cattgccgcc ctcgctccta caaggaacat
    12541 acggtcgtct cggttacttg agcatcggag tgactatgcc tatcccgact cattgctctc
    12601 gtccttcatg aggagatgaa tcatgcgcac ccgcctgtac cgctccttcg ctcttaccgc
    12661 acttctactg acattgtctc cactgcactg ccgggcgatc gacccatctc ccaatcagat
    12721 ctctgccgag tcgttaaatc agagcttgtc tgatcaggac ctgcagcagt ggtaccatct
    12781 gtcggccggg acccagctca ttccttacga ttggctggta gcactacttg atgagtcgct
    12841 ggcaaaaacc ttcgcggtga cggggcttgt cgaagatcct cggcatccgg acaaacttcc
    12901 ggtcggcttt gccaaaacgg aagggccgaa cgtcccggtg cctctggtcg gcttcacctg
    12961 ttcgttttgt cacacgaccc aatttcgcta caaggggcat tccatcagga tcgagggtgg
    13021 cccctcgctc caaaataatg cggccttggt gaacgccttg atccaacggc tcggagccct
    13081 gacgcctccc gatgtgtccg catttctcaa cagcctgaaa gcagaggctc ctcctgaccc
    13141 ctttaagacc tttgccaatc gcgtgcttgc cagccgcgga gaagccgtga cggcttatac
    13201 gctaacgaag ctcgcccagg atgtgcgggt ccttacccag gcgctcgtgt cccgcagtgg
    13261 gaaagacatc tcgccccagc aatgggggcc aggtcgattc gatgcgctgg gtcgcggtgg
    13321 gaataccgtc tttgcaccgc tcaatcccga taatctcaga cctgccaatg cccccgtaag
    13381 tattccggca ttgtggggag tgtgggagtt tgactgggtg cagtgggccg gttcgattca
    13441 acatccgttg gcgaggaata tcggacaggt gatcggcgtc aatgccgggc tttttagttg
    13501 ggcacgtccc ggcgttccca ctccctcaga caagaacaag gtgttccact catctatcga
    13561 tgtgacttcg ctcaccatcc tcgaaaatct cgcacgccgc ctgccgccgc cgcagtggcc
    13621 gtctgtcttc cctcctatca atcgggaact agcagcccgc ggcaaagacc tgtatcacgg
    13681 caacaaggct aagggaattc cgaacctgtg tgcccattgc cacgtcccct caaaaatgtc
    13741 tcactcctcg gccaatagcc caagtctgca gatcacgatg gttcccctac aggaaatcgg
    13801 caccgactcc ctctatctgg agaatttttc tcagcgaacc gtggacacga gcttcttagg
    13861 acgcggacgc atttccgcgc gggaagcctc ggaatatgtc acgaccgaat tgatgaccct
    13921 ggacaagacc ggcgacctaa gcagctatcg cgaccggccg aacatctggc gggacaaggc
    13981 ccaatacatc gcccgccccc actttggcat ctgggccacc gccccctacc ttcataatgg
    14041 ctctatcccg actctctatg aactattatc cccagcacgg gagcgtcgcg cttgcttcgt
    14101 gctcgatccg aacatggaat ttgatcctga aaaggtgggc tttgtcacag gagactgtgc
    14161 caatccctct caatcaccaa ccttgccccc acgcctcgaa ttccggacag cattaccggg
    14221 gaacagcaac cgtgggcacg agtttgcaaa cacgccggat tgcgacagcg caaagagcaa
    14281 tggagttttg ggatgtgagt tgccggtgaa tgatcgcctg gccgtcatcg aatacctcaa
    14341 gacctgtgat ctcgaccgct tgattttacc gaacgcgccg gcctgtccga atttcgacta
    14401 gcagaggacg tgaaaccatc cggtgccgct cgtacatgac ggagatgcat cgaaggaggc
    14461 caccgacgca tgaccgacct tctctccagt gaccactcga ttctcgagcg tccgttcatg
    14521 gagtttcgcc ctttcggctt gaacgacaag ggcgagaaga tctctgatat cagcggcgtc
    14581 gtcgtccaat cgaacgtgga ttatatgtgc gactatttaa gtcgcaccgc cggttcccaa
    14641 gcagcggcag cagcggtgga tgaactctgt cgcctcctga acgcacggct tcccgaccgc
    14701 acgtaccacg tcacacccga tttccttcgg aacatctgga atagttactc gtatgaattc
    14761 gtctgttatt tgagggaatt ctgcgaacag ctatccggag accctcagtt ccacatcaat
    14821 gtcggaacgg accgcaaggt tccacctttg attcagatcc tctgccgccc gttttcgacc
    14881 caacagctct ataaaatgtg gccctacttc ggacggaaat atgtccgcga tgtgttggaa
    14941 ttcgaggtgg gccgggtgac gagacgctcg gcggttctcc gcatgacgtt tacagaacga
    15001 gcgttggtcc aatttgggcc atatcgaaaa cgctgtgtcg acgtcatttg tctctcctgc
    15061 aagagcagta tcgcccgcgt acaaacccag ttgcacggca ccccggccgc tacggtcaaa
    15121 gatctttcgt gcacggccca cggcgatgcg tactgtgaat gggagtttac ctggacaccg
    15181 caagtccgga gttccatccc ggtggccatg tggacgctgg ttgccggcgg cacgtttacc
    15241 tatctccatg tgcgctggcc cgatgttccc acattcgaag cgctgggcct tgccgccgtt
    15301 cccgcctcgc tcctgtggtg gatgattacc agccacatgc ggcaggccac caagccgctt
    15361 caacgcctga ttaaggacca agaacaggtc gttgatgcga gacacgagga gctgcgcgag
    15421 gcctacctcg agcagcaaag tacggccgtg atgttacgtc gaaaagtgaa tgacctcacg
    15481 acgcttcacc gcgcgggatt attgttcagc tcgacattcg atcgggaaga acttctgacc
    15541 aatgtcctgg atacgatcgt ccgcgatttg cactacgatc gcgccatgat tacgcaattc
    15601 gatcgaacgc gtcaggtctc acacgatttt cgagtgcgag gcatgcctca ggaagtggca
    15661 gattttttac gcacgcaaga agtgtcggtc accgaccccg agacggtgga gggcgccgtg
    15721 ttcttgcgtg gcgaaccggt gctgacgaat aacgtgcatg agatctggga tcggttacac
    15781 ccgttcgatc agaaattgat cgccatggtc aatgtaaaat ccttcattac cgtcccgctc
    15841 aaaacccacg acgccgtgat cggttcactc tccgtcgatc gcacgcacaa ccaagcgctg
    15901 actcaggacg atcttgatat gttggtcacc ctggccagcc aggtcgccat tgccctcgat
    15961 aatgcccaag cctatcgaga gatcgaagcc ctcaacgccg gcctggaagt ccgggttcgt
    16021 gaacgaaccg ccgaattgga agccgctaac acccagctga agcaaatgga tcggctcaaa
    16081 tccaaattcc tcgcccacgt ctcgcacgaa ttgcggaccc cgctcacgag catcgtcggg
    16141 tttgcggata atatgctcga gggactggtc ggttcgctca acatgaagca ggagcaatac
    16201 ctgactcgga tcagagccaa tggaaccagg ctcgcacgaa tgatcacgga tttactcgac
    16261 ctctcccgcg tggaggccgg caaactggtg ctctccttcg accacgtggc actgcaaacc
    16321 gtggtcagtg acgtcatcga gcaacttctc ccgttggcca tcgccaaaca cttgcagatc
    16381 gaactccgga gtcctgaccc ggccctgctc gtctgggcgg atccggatcg cgtcagccag
    16441 attttgacga atctcctgga taatgctatc aagtacaccc cggacggggg acacattacc
    16501 gtagacctct cagtcggtga tcatgagatg gcccgtgtcg tggtccgtga caccggtcaa
    16561 ggcatccccg ccgacgccct gcctaaactc ttcgatccgt ttttccgcgt gcaccatcaa
    16621 gagcggagcc agacgaaggg gctgggcctc ggtttggcga ttgtgaaaga tttggtggat
    16681 ctgcatggcg gcagcatcat ggtgcacagt acggtggacg aaggcactga atttacattc
    16741 actctgcctc tcgactcacg ggcaccggag cccgctgcgc aagtacccgc cgctcgccgc
    16801 agactgctgg tggtggatga tgatgcggac atttgcgacc ttttgcgaga ccgtctggaa
    16861 tcagaaggat ttcacgtcga cacggcagcc gacggccgga cggccctccg catcctggcg
    16921 gagacgccgg tcgatggcgt cttgctggac attgccttac ccgaagtgga tggatttgag
    16981 gtgttgcggc aactacggcc ccagcaacct gcgttaccgg tggtgatgat gaccgccgtg
    17041 gaggcattgg accgcgccat ggccgcggta gaagccggcg cacaaggata tctcctgaaa
    17101 ccattcgacg cggcccgctt gcgacaaatc gtcgatcact ggttcctcgc cggcgcaagc
    17161 aagaccgacc ccacaagtgg acgataaccc tatgctcttc tctcgcagat tccgcatcgc
    17221 cctggtactg tccctggttc tgcttcccgt gagtctttcc ctcagtgtga cacctgttca
    17281 ggcgcagact ccccgccttc aagggcaatc ggcatccgcc gctgctatgg gaaatgcatt
    17341 tgtggcgcaa gcagatgatc cctctgcact gcactacaat ccggccggta tgactcagtt
    17401 gcatggattc caaaccctct ttgggacctc gctgatcggc gggaccactc aattcaccgg
    17461 tccaagcggc gcccaggcga cgggagatcg caacggaagc ctggcctacc cgccaccagg
    17521 gcacgtgtat ctggttgcca atctgaaaga cctcggcttc gccgctttag gagatttcag
    17581 cgccggtatc gggttaaata accccttcgg ctcgttgacc cgatatccca acgatggacc
    17641 gtttcgcagc gccctgacct tcacgacact gccgctactc gatatcaaac ccacaattgc
    17701 ctacaagctc aacgaccaac tatcgttcgg attaggtgca gacatctaca ccttctcagg
    17761 cctgttcggt gaagggcatc tcgagcaaaa atcggtctgg cccggaggat taggcattcc
    17821 cgccggctca ctcgttgaaa tcaacgggag tgataccacc gcgggcttca acgtcagcct
    17881 cctctacaca ccctatcgca acagcgaggg caaacccctc gtcaacatcg ggatggtcta
    17941 tcgcagtcag gccacctttc atctcaccgg caacttcttg gcgaatggca cttcgatcgc
    18001 cggtacggca gcgacctttg tcctgccgca agtcttttcc ggtggcatcg ccgtctggcc
    18061 ggtacgtacc cctgatcgtg aatggaaatt ggaattcgat gtggactatg tcggatggaa
    18121 atcaaaccga acgctcgata ttcatttgac gaacggcacc gtgctaccct tcccgcaaaa
    18181 ctggcagagc ggttacacag caatggttgg aaccgaatat cgatggctgc ggctggcttc
    18241 actgccggat tgggatgtcg ccctgcgtgc cggctacatg aatcagcaaa cgcaagttcc
    18301 cgatcgaacc ttcaatcccg gggttccatc agccaatacc cacattccct ccgtcggcat
    18361 tgggtttgcc tgtcatgagc atggatattt cctgggcttg atccgatgcg gtgagttggg
    18421 catcggtcca ctcaagccaa aactcttcgc cattgacctg tcataccagg ccgcgttcta
    18481 tgaagtacgt accgtcacgg gcaatcagaa tccgaccgtc aacggtcgct acgacacatt
    18541 gattcacgcc ggctcgctct ccttgcgatt caactactga accaatcagc catttctcaa
    18601 ctcgacacgc cactcgtcgc cccgactttc gagtacgcaa gggcacagtg attgcttcac
    18661 tcacatctcg atagcaacac gagcgaagca acgtgcccag ttccatacga ccaaagcggc
    18721 gtggcgtgga gccggtctcc gatcgtcggt tgcgttaacc gaccggattt ctcgcctcct
    18781 ggattgtgcc catccagcgc tgagtagacc gccttcatct ccacgccaac tgccgcgtct
    18841 tcgttctcaa cggagacgcg gctcctttcc ccgcactccc gagcgggggc tctcatcgat
    18901 ctgaacgtgt cagaatttcc tgagtctgca catcactcta tccgctatgc gctgccttcg
    18961 cacaaacgca tggcgggcgc attcgtatcg gatccgatac gccacgaatc caatccgata
    19021 cacctttcaa ctcgacgcag gcccgcatag cggatcggca cgctagcctt gatgcgagat
    19081 gtcgtgagaa tgtctacaga tcttcccgcc cgcacatccg tgctcaaaca accgccgtcc
    19141 atggcacagg ccttgcgcgt cacgtagcca attacaactt ctcttcggct gacagtgatg
    19201 agccaacctc accttcagga gggatcatca tggtcgcgct cttttttctc ctactcgggg
    19261 gcctcgtcct tctagtcgca gcctgtcgta tctggatgac cgcacccact ggaacgttca
    19321 aggagaccaa tgcaccggta gccaacaact caggcatggc cgaaacacag cacagggttt
    19381 gaacagaagg ctgactcaac ggagtctggg gctcaaccaa ctgcaaccac ccagtaatct
    19441 gttggagatt ccggccgagc cccatgtcgg tgtggggggg gacaagggct tctatggtga
    19501 cgagaggatt acgcgccagg cctgtagctc tcccacacct cgctgtcttg cttgcttgtg
    19561 tgctagcaca agtgttcatg ccggggttgt gccaggctca accatcctca ccgatcacct
    19621 cctcgggcct gaataccacc gtcaccacaa gcggaaattc ttttaatatc acgggcggca
    19681 ctcgtcccgg tggtgggacg aacctctttc atagcttcgg cgaattcggc gtgcccgcga
    19741 atcaggtggc caattttctc aacgattcag gactggccac cacgaacatt ctgagccgcg
    19801 tcaccggcgg gaccccttcc aacatcttcg gcaccatcca gacgaccggc ttcggcaacg
    19861 ccaatctgtt tatgatgaat cccgcgggga tggtcttcgg acccaatgcc tccttgaatg
    19921 tcgggggctc ggtgcatttt acgacagcgg attatctccg cttgggggac ggggcccgct
    19981 tcaacgccat gccggggccg caggatgcag ccgtctccag cgcaccggtc gcggcattcg
    20041 gctttttagg atcaaacccc tccgccattg tggttcaagg gagtcaactc actctcgccg
    20101 aaggcaacac cctctcactg ataggcggta acgtccaaat cgccaacggg acattatcag
    20161 atggcgcgat ccagcccgcg cgcctctcgg caccgggagg gcaaatcaac ctggtcgcgg
    20221 tcggatcccc tggggaagcg ttgattagca atggagcggg gacgctcgcc gagccgatgt
    20281 tgaccggctt caccggactc ggaacgattt cgctttcgca cggcacgaca ataggcacaa
    20341 gcggcgatgc tgcagggcgc atcgtcattc gtggcggaca cttcagcatg gaggatgcag
    20401 gccttgaggc catctcgaca tccgtctctc caaactcgct cccctcttcc tccccgagag
    20461 gggatatctc gattcaggcg gaagaggttt cgttgtcgaa cggcgctcac ctacttacgt
    20521 ccacgatcaa tggcacggcc ggtaatatcg cgctggaggt gggtactctg cgaagcaatg
    20581 tcggaccggg cggcctcccg ctctcgggtg ccgcgccagt cactattacc agcagcagca
    20641 cagggctagg cggacccgga agcatttcgg tcacgggcaa cggacgggcg gcttcggatg
    20701 ttgtagtcct cagtaacaca caggccgtga ctactgtgcc tcactccgct caaccgacaa
    20761 ttgtaccagc ccacattgat atgacggcag agcatctcga actcaggaac gggacggtcc
    20821 tcaagacgga taccacggga ggagctgatg ccggatcgat cacattgaaa gttggaacgc
    20881 ttgctacgga agccggtcct gacggaagag tgcttctctc aagcagcagt aactgcggga
    20941 ccggatgtgt ggggggacag gccggtgaca ttaccatcca gggcattcca ggaatcactc
    21001 cggcggaaac ccacttgtat gtccccatcg tcagacctga ctcccctccc accgtggcca
    21061 ttagttatca gttggcgaga aatatggacc ttcgaggcac agacattcgc tccgaagcga
    21121 tcggtaatgc gccgggcgga caagtcatca tgagggcgca gggatccatc tcgctcgccg
    21181 ataccaccat ctcggtcgcg acacaggact ttcaaatcga cggacctaag ccaagcggcg
    21241 aacttgtccg caaccaaggg ttcagccgga ttgatatcct cgcgcatgat gtcacgttaa
    21301 aagacagcac cgttcgggca gacgcaaatg tctcggatat cggctcctgc ccgctctgtc
    21361 tcggggggcc cagcgcagga gagatttggt ttcgagtcgg caattcattc actgccgata
    21421 attccgccat tattaatagt ggcaaaggca gagcccaggc cgggctcacg aaaatcatca
    21481 gagaccactt cttttcattt ggcgccattt gggagccgga ttaccccgat tatcctacga
    21541 actcgattac cctcaatcat tcccaaatca ccgtcgaatc tccgcattca gggattcccg
    21601 gatatcttcg actccgcgcc gacaacgtga cgttgaacca ttccatcctc aactctcaag
    21661 tcaacgacgt gtcgaactcg cgagggctgg acgggcaatt gatcgatgtc cccggcgccg
    21721 gcgaacgcgg acgagtgatt gcagacggcc gggacgtaca gggcagcgtc ttggtttcgg
    21781 caaagacgct cgacatcacc ggcggcggaa ttatcgcgcc aaccacaggc agccgcatcg
    21841 cgagtcgcat cgagttgctc gcgaacgagt tgacgaccca caggggaact gggccgggag
    21901 gaacgtttga tgccccacgc atcttagatg ccgccgaccc cacgcgcgtg gttctgtcga
    21961 gcagcagcac gggaagcgga ggcgcaggca ggatcagcat cgcaggcgag ggcgtggcta
    22021 tgcccgaggg caccccatac cggcccgcgt cgtccattca tctcgatggc acggccctct
    22081 tcaccgatac gcacagcgat gccctgggag gcaaaattga gatgatctcg cgcggcccaa
    22141 tcgtcctgca tgacaccacc gtctccgcca atgtcacaga tgtgcggccg gcttctgccg
    22201 gcttgcaaga gcaaggtggg aacatcagtc tctcggcagg gagtctcttg gtacaaggtg
    22261 gcgggctttc ggcactctct cgcggcacac agaccggcgg caacatcgcg atcacggtgc
    22321 aaggcccgat cacgctggaa tccggtgcgg caatttcggc cagtaacacg gggtcggcaa
    22381 atgccggcag cgtcaccatc cacgccgggt cagagtttgt gagccgggat gcttccgtga
    22441 cgacggaatc cattcacgca agcggtggca acatcttcat tcaagccact gattccatac
    22501 gactcgtgaa tagccgcatc agtacctctg tgctaggtgg tccgaattca tccggaggca
    22561 atattattct tgatccggcc gtggtcacac tgcagaacag tcaggtactc gcgcaagcgg
    22621 tgcagggggc aggcggcaat attcgtatca tcgcagggac attcctggcc gatcagacca
    22681 gcgccgtcag tgcgtcgtcc gaattcgggt tgaacggcac cgtctccatc caatcgccgg
    22741 tctccagctt gagcgggacg ctcgcgacgc tcccgcaaag caccctgcaa acacagcaac
    22801 ttgtcacaca acgctgtgcc gcccagggaa gtggtcatct cagcagtctc gtcgtcgcgg
    22861 gacgcgatgt gctgcccgtc gaaccaggcg gatggttgat gagcccgtta agcgtcttcg
    22921 ctgtggatgc ccatgatgac ggaggtcggc ctgtcgctga gacgattcct gatgcagccg
    22981 aagggggcaa caccctggtg gaactgacgc aggaacatcc gactcctgag ccgcgctcga
    23041 acttcactac cccgggagga ggctgtcgct cataacgggt tgagccggcg cgccggcgga
    23101 caggtacaac acttggcttt gcgcatcgtt acggtcccat gtgtatgtcg cgttgtggta
    23161 ctgagccttt gccttatgac attccaagcc ctggctcaag tggcgcctcc cctcccgccg
    23221 atttttgacc cgaccgggaa atcggggaaa ccgccggccc tgctcaaaga agacttcaat
    23281 actcctccct cggagccacc cagctcgata ctccccaaag taccgactac gcctcccgcg
    23341 ctgcccgaca ataagttggg ggcatttcga gtgttcgtgc atgatatcca tgtgaccggc
    23401 agcaccgtat tttctgaaac tgaactttca gaagtgaccg cgccgtatcg caatcgatac
    23461 ctcacaacag aagatttgga gaaggtgcga ctcgccctga cacttttata tgtgaacaac
    23521 ggctatctca catccggcgc agtggttccg gaccaggacg tgacgttcgg cacgattgtc
    23581 attcagatgg tcgaggggaa acttgcgcac atcgacgtcg aggggaatgc gtggtttcga
    23641 aatgcgtatc tccgcgaccg tgtggcgcgc ggggtgtcga cgccgctcaa catccacccg
    23701 cttcaggagc ggatacaact gctgcaacaa gaccctcgca tcgaacggat caatgcagaa
    23761 ctgaaacctg gagacgttcg cggcgagagc gtcttgaacg tgcgcgtgaa agatgccaat
    23821 ccctttcggg cctggctgga gttcaataac catcaaaccc cgacggtggg cgccgaacgc
    23881 ggtctggcga ccgtggcgca tcagaacgtg accggtcacg gcgaccaatt catgtttacc
    23941 tacggccgct cccacggcgt caatcccatc atcgatacgt cctatagcct accgctcaac
    24001 aggtatgaga cgacgctgac tgcctactat cgacgcaatg cctttctcgt cgtcgaaaat
    24061 ccttttcgcg ccttggattt gaacgtggac tcccaggtga tcgggctcgc tctgcgacag
    24121 ccggtctatc gaaccgtcac cgctgagttc gcactgacgt tgacggggga gcatctattt
    24181 ttgaagacca catccgcttt cgatgctccc ggccttccct cgctgttcat tcccggttcg
    24241 tccacgacag gagtggccac cgtcagcgca ctgcgattca gccaggagta cacacatcgc
    24301 tcttcatcct tggtatttgc tgccctatcc cgcgtcagtg tcgggttgaa tgtattgggc
    24361 gccacgatca atagcggacc acttcctgat gggcagttcg tgtcctggtt gggccaggct
    24421 caggtcgtaa agcgattgga tgactggtgg ggcgtgcaat tgttggggcg tgtggcagcg
    24481 cagttggcaa gtgaccgact cttccccctg gaacaaatgc cggtcggggg ccgtttcagc
    24541 gtgcgcggat atcgcgagaa cacgcttgtg cgggacgatg ccgtgctggc ttcattcgag
    24601 tcgcgagtgc cgttgctccg gttcccatcc ggagaagacc ggctgcaatt cgccccgttc
    24661 gtcgatgtcg gccacgcctg gaacgccaaa ggccacaccc cagatccgca tacgttggcg
    24721 agtgtcggag ctggactccg ttggatgatc ctccctcagg agcgggcccg cttcgaggtg
    24781 tattgggggc agcaactcaa tcacgtccgc ggcggggaag gcaatttgca agatcatggc
    24841 attcatctcc aacttgttgt gcaggtgctg taaatgaggc atcaccggct cacagtattc
    24901 ccgccgccct cgcatctgct tcgatacgga ctcaaggggc tcagtctgtg cctgattatc
    24961 ttcttctgct gtaccgtttc tctggctgcg gacagtcagc cttcggctgg tgacttgatg
    25021 cagcgcggtc gagcggcggc ccgagaagga tcctatgaag aagcgctcct cgcatggaag
    25081 gcagccgcgg agttgtacga ccaggccggt gagacgaaga accatatcca agcgctgaca
    25141 cagtccgcgt ttgccgctcg taccttgggg catatcaacc aggcgtttct ccaagaggaa
    25201 ctcgcgctgc acctcgcacg ccagctgcgc gattctcaat ggctggtcat cacgctctcc
    25261 gaattaggca agacctatgt cacgaaccat cagtatgagg tggcagcgga ctatattggt
    25321 caagcacttg aaatcgcaca ggcacagtca ttccgggcgc tgagtcccgc actccagaat
    25381 gatctcggga tcgttttggc cttgcaggga cgcccggaag aagccctggc ggcattccac
    25441 caatgtgcag tgagtgcgaa acaagagggg ctcatcccgc tcttcattcg tgcccgtgtc
    25501 aacgcggccc ggatggcgat tcaggttgcg cagttcgata cagccacatc ggccctggcc
    25561 gaagctgcag atcaacttgc cggctccgcc tcctcctacg aaaaggccga aggactcgtg
    25621 aatctggctt tgggatatcg cgatctggcc ttggctcatt ctggctctca cgcgtccgcc
    25681 ctcaagcgat ctgcgctctt cttgcaggaa gccgcaggga tgacacaaca cccgggcgac
    25741 gcgcgcctcg catcatacgt ttacggccat ctcgggcacc tctatgaagt tgaacgccgg
    25801 tttgatgaag cccttcagtt gactcgacaa gcggtcttca ccgcgcagtc ggctcgcgca
    25861 ccggagtcgt tgtatcggtg gcaatggcaa tgcgggcggc tgctgaatcg tctcggccaa
    25921 ctcgacgacg ccctgtcggc ctatcaagaa gccgccatca ctctgcatcc cattcgaagc
    25981 gaggtaacat tcgccgtcca gactagcccg gattcgcatc agccatccat ccgcgcgtta
    26041 tattttgagt tagccgactt gcttctgcgg cgagccgcgt tgatgcatga aaaccgagag
    26101 gccgaggcgt acttgcgtgc ggcccgggat gtgattgaag cctttaaggc tgcagaactt
    26161 cgagactact ttcgagacga ctgcgtcgat cagatgcagg cccgcatcac aaaactggac
    26221 gcgctctcac cttccactgc cattatttat cctatcgtct tcagcgatcg caccgagctc
    26281 ctcgtcagtc ttcctgacgg gctgacacgt cattccgttc cggtgacggc cgccaccttg
    26341 acggatgaag tgcgtcgctt ccggcatacg ctcgaaaagc ggacgactcg tgaatacctc
    26401 cctcacgcgc agcagctgta cgattggctg atccgacctc ttgatcctga tcttcgccgg
    26461 ctccaagtaa acacattggt ctttgtcccg gacggatcgc tccgcaccat tcccatgtcg
    26521 gccctgcatg acggaaagga gttcctcatc gagcactatg ccgtggccat gtcccccggc
    26581 cttgatttga cggaccctca accgattgat cgtgccaagg tgcatctgtt gtccagcggg
    26641 ctgaccaaag ccgtgcaggg gtttcctcca ttgccccatg tcgccgacga gctcgattcc
    26701 attcgtgcgc tgtttaaggg agagcaactc atcgaccagg agtttctgac gccccggttg
    26761 gaagaggaat tgaagggggg gcgttacagc atccttcaca tcgccactca tggacagttt
    26821 gccccggacg tcaatcagtc gttcctcctg accttcgatg cccgtctgag catgacccag
    26881 ctggagcgac tcgtcggcct gtttcgtttt cgacgagagc cgcttgaatt gctcaccttg
    26941 agcgcctgtc agaccggcag tggtgacgat cgggcagcgc ttggactggc cgggatcgcc
    27001 gtcaaggcag gtgccagaag tgccctcgcc acactctggt ccatcaatga cgacgcctcg
    27061 tccgaactcg tctcagaatt ttaccgtcaa ctgcatgacg catcggtctc caaggcgcga
    27121 gctttgcagc atgcgcagtt gaagttgctg tcagatcggg tgtatgaaca tcccgcctat
    27181 tgggcggcat ttttattatt gaacaattgg ttgtgacgga ctctggaaca gggtgatcgc
    27241 ttggcgacgt ggctctaccg ctccatggct cgaacattcg tagccacact ccttttcacc
    27301 gtgtcgttgg tgagtaccaa tgcggccgcg ccggaaggtg tgccggacgt cccccagtac
    27361 aatgcacccc agaagatgac gccccgggca cgtctgggcg gaagcttacg cggcagtgag
    27421 ggtgaagatc ctgccgtcgc ggcgcttgtc ccggaccacg tcggcatcac cgtcaaacag
    27481 catccggcat taaactggtt tttgtccaag catacgtcat tgccgatcac ttttaccctg
    27541 atcgatgagc gctccattca tgccttggtt gaacgccccc tcgcgccgcc tcatcaagcc
    27601 ggtgttcacg ccgtcaagct cgaagacctg ggggtgacac ttcaaccgaa cattcagtac
    27661 cgctggtata tatccgtgat caaagatgcc gactcgccct cacaggatat cgtcacgggt
    27721 ggaatgatcg aacgctgcga attcagcgag tgctcgatcc taggcgccat gacgacatgt
    27781 acgcgcgaag ccgtcatgac cagcgccgcc aaaggattct ggtacgacgc gatgggatgc
    27841 ctctgcgatc tcattgactc caatccggca gataccgcgc tccggaagca gcgtgccgcc
    27901 ttgctcaggc aagtgggcct gcatgatgtg gcggactggg atctcgcaca atcccatgcg
    27961 cgacaagggt gacgcatgcc ataccggcga gtcagtttcc cactggtctt gatgatcgcg
    28021 tggctgaccg gggggtatgc gtcgcagttt ccgttcggcg cccctgatag tatcgcggcg
    28081 gatcctctcg tccctcttga attgcgcctg cccgaataca aaccgaaaaa ggcagatgcc
    28141 cctcgagccc gcatcggggg acacagccgt ggaacagaag ccggagcccc tgtcctcatt
    28201 gctctggttc cggatcacat tgcctttaca gtcaagaatg atcccaccct ctgttggtac
    28261 cagtctttgc atacctctcg gccaatggtt ctgacggtgg tcgattcccg cggtatccgc
    28321 cccgtcctgg agcattcact gcccacgcca gttcgtcacg gaatacagtg cctgaggccg
    28381 cgcgagtatg gggtcgaatt cagagtagaa gagtcgtatc gatggtatgt gacggtggtg
    28441 atggacccca acagaccctc gctcgacgtc gtcgcaggcg gaatgatcga acgactctct
    28501 ctcgatgaag cctgcgctct cggcatgccc tgcccctcct cctcttgcga taccgacggg
    28561 atttatcgct atgcggagtc aggtctctgg tacgacgcca ttgcctgtct ggtggaactg
    28621 ctcgagcagg agtctgacaa ggataggctg cggctgatgc tggaccattt gctgcaccaa
    28681 tccggtgtcc acctgccggg agagtcgtca ccgtaataac aacgttgaga ctcgcactca
    28741 ccggctctct ccattcttca ctgccactgc ttctagccgt ctaccgatca gcgcgcctcc
    28801 ccctaaaaac atgtagcccg ctgatcgttg tccgttattt gattttctcg gttgaagacc
    28861 accgtgattg ggtatctcat cagatacgct aggatcggat ccgatacagt gagacgggca
    28921 accgctcagg gatacgactg ttacctcact cgactttcca aacatttttt ccatcgagcc
    28981 ggagctgtgc gtaccgatcg ttgtggcacg gctgttgctg tacctttgga catgtagacg
    29041 attctttggg cggttgtaga aagacacagc cccccttcga aatagaaagg agcctgacat
    29101 ggaactcgtc atgggcggtc tcctggtggg cgtcagtggc atgttggccg tcttgatcgt
    29161 cgcggtctgg aaagacagcg cctctcatcg tacgggggcg catccgtcac accggagggt
    29221 ttagccgctt gatgttcgtt tgaacgaagc ggcgcggcag aaaaacacag ccagaacgga
    29281 tcgggaggcg tacacctcca tacgcctctc gtgcaaagga gttgcaccat gaaccggttc
    29341 gtgtatttga gacctcaaaa gcgccagcgc atgactgtca gcctcccggc ggatctttta
    29401 gaacggatgc gcgatgctgc gtactggaca tccgggacca ccatggccgg cctcatttcg
    29461 tcggccattg aagatctgct ccacaatctg gaatcgcaaa atggccgacc gttctccccg
    29521 cgcctccagg acctaaagcc aggccgcccc aggtccaata aaccggatca atcgtctgta
    29581 tctgaaaaca tacagtctgt atcccgttag atacgcacag gctcgccccg attccccaca
    29641 ccacctttct tcgtgccacg ttcatccaaa tcaatcggat cttttcggaa tctcaacccg
    29701 ccgtttcttt ctctatccgc acgaaacaag catgcctttt gcgagagaat ttgttgagtc
    29761 aaagtgggtt cactcctttt ctccgtcaga caacgtccga ctccgccgct aaagggctca
    29821 aggtatgcca tgcgcactcg gaccgcacga gccgaaacca tcgtccattg tccatttact
    29881 gccacgcaac ctgagcccgc attggcggta cacccaatca cgcttcgctg ggatcactat
    29941 acgcgcgcat tggcgagagg tctcatgagc gtatgctggg ccttcgccat cgaggcacat
    30001 tcgccgatcc ccacctatgc tgcaccacaa gcagacgccc cggcaaacga agagctggaa
    30061 ctactcaaag aagaagaaac ggttagcatc gccacgcgtc acgagcaacc gatttcacaa
    30121 gcgccttcaa acgtatacgt cattacggat gaagacattc ggcattccgg cgccaccgat
    30181 attcccacca ttctccggcg cgtgccgggg ctggatgtca tgcaagtcac cggggctgac
    30241 ttcaacgtca gcgcacgagg cgacaaccag ctcttcgcga ataagattct cgtcatggtg
    30301 gacgggcgat cgatctacat cgacggccag gggctcgtgt tctggaaatc actgccggtg
    30361 acgctgccgg agatcaaacg cattgaggtt ctcaaggggc cggcatccgt ggtctatgga
    30421 ttcaatgcct tcgacggggt catcaacatc attaccaagt ccgcgcagga gatgaagggt
    30481 acgacactgc agttcggtgg tggggaactc ggcaccattt ccagcgctgc ggtacaggcc
    30541 gggtcggcag gcaaactcga ttatcgccta tccatcgggc acgaccagaa tcagcaatgg
    30601 cgaaacaatg atgcgctggc gttccgatcg aataaattca acgcacagac acaatacaac
    30661 ttctcgggcg acgccatctt gcgcgtcgct ggcgggttca ttgatacaaa caggtttgac
    30721 ggtcccgtct caaacgtgca agtccctcgc tcccaattca atcaaggcta ttccgacgtc
    30781 cactaccaat atcggaactt ctctcttcgc ggctggtggc agggcaatga catccccgtg
    30841 gaatcttcca cccatccgct cctcgcccca tttgtccggc agaccaatgc gacgggtggc
    30901 tcgaatgtct cgttcaccac gaatacctat aatatcgagg cgcaacacag tctcgacttc
    30961 ggcccggcca accggctgag ttacggcgtc aactaccgct ataactccgt cgacggcgca
    31021 gccgtctcag aattgggccg tgaagatcga ctgggattcc atctgcagga tgagtggaaa
    31081 atcctgtcat cgcttactct tgtggcggga gtccgatacg acctgcatac ccgaatcaac
    31141 ggcacctgga gcccgcgcgt tgcccttatc tacaatctga ctccggagca tacgttccgt
    31201 gtcagcggat cagtggcata ccggccacct acgctgttcg agtccaatct ggacctgcga
    31261 atcttaccga ccgtccctcc cctgttcgcc cccattccgc tcttcggttc acagaggctc
    31321 aatccggaac agattatttc ctatgaagcc ggctaccagg ggtggtggct aaaacaccgg
    31381 cttcggacca ggctcgatct gttttttaac catctctcag acctgatcaa ttttcaaacc
    31441 atcggtgcca cacgcacgtt ggtgaacggc ggggaagcgg acatctacgg aaccgaggct
    31501 ggatttgaat ttctggcgac gagatggttg agcggctttg ccaacgtgtc ttaccaaaag
    31561 atcgggcaga cctttaccgg cgtctcacgt cgaggcggac cagactggaa agccaatgtg
    31621 gggttgcgtg gcgactggga caatgggctc aatggtgaaa ttgcggtgca ttacgtcgca
    31681 ggcgccacct accccctgat tgaattgttt acggccctcg ctccggtcct gcccgcgccg
    31741 atcagcccca acatcgatag ctataccttg ttgaacctcc gcggcgggta ccgattctgg
    31801 catgagaaag ccgaggtcgc cattgccgtc tataacgccc tgaacgaccg ccacaaggaa
    31861 catccgttgg gagacacgct gggaagccga gtcatgggtt ggctcacctt acggtattga
    31921 gttatgcatg ctgaatccaa gggagtatgg cagacgatgg tcgcggcatt catgacagtg
    31981 agcatcagtc agttcgctgc cgccgaacct ccggccatcc gggtcgagga ttccctgacc
    32041 gttcccgcca ataacgatct ggagttgttg aaagaagagg aaaccgtgag cattgcatca
    32101 cggtacgaac aacccatttc gcaggcaccg tcaaacgtct acgtcgtcac ggatgaggac
    32161 atccggcagt ccggcgccac cgatctccca accgtgctcc gtcgcatccc gggtttggaa
    32221 gtcatgcaaa tgaccggcgc cgatttcaac gtcagcgcgc gaggtgacaa tcagcccttc
    32281 gcaaacaaga tgctggtcat ggtcgacgga cgttcgatct acctcgatgt gcaaggcaac
    32341 gtcttctgga aatcccttcc cgttacactc ccggagatca agcgcatcga agtgctgaaa
    32401 ggccccgcgt cggccatgta tggatttaat gccttcgatg gggtcatcaa catcatcacc
    32461 aagtcaccag aagagatgaa aggcaccacc cttcaattcg gcggagggga gcaaggcacc
    32521 atcagcagcg cggccatcca ggcgggtaca gtcggcaagt tcggctatcg actctctatc
    32581 ggtcgcgatc aaactcagca atggagagac ggcgacgcgc ttgcgtttcg cgcgcacaaa
    32641 ttcaatgtcc agacggacta tgcgttgtcc tcgacgtcga agctgcaact ctctggaggg
    32701 ctaatcgaaa cgaatcggta cgacgggcaa gtcggtgaag tcaccagcaa ttccattcgc
    32761 ccttcctttg ggtacgccaa tgcggtctac gagcacggcg cctttctcgt tcgtgcatgg
    32821 tggtccggat atacagatca tgccaccatc aaccctcttc cccaattggc cggccttctc
    32881 agcgtgaccg atcgtaacgg cgtatcgacc aatccgtttt caggcaatac gtacaatgtg
    32941 gatgtgcaac atgcattgga tatgggtgcg gccaatcgcc tcctctatgg tgcgaactac
    33001 cggcacaatt cgctttcgag tccggccatc gatcaattca gcagggaaaa ccggctcggg
    33061 ttgttcttgc aggacgaatg gcgggcatcc tccgcgatta ccgtcgtcgc cggtatccgg
    33121 tatgatctcc acagccagat caacggcacc tggagtcctc gcctcaccct gttgtatcaa
    33181 ccggtagagg ggcacacttt tcatctctcg ggatcggcgg cctatcgtcc tcccacgctc
    33241 ttcgaatccc atcaggacca acgagtcacg acgaatatcc cgaccggttt acccttccca
    33301 ttaccttcgt cagtctcttc aaccgtaccg gtgacgggct cgaccggtct cgctcctgaa
    33361 cggatcattt cgtatgaggc cgggtatcag ggttggtact ggaaacatcg catacgcgta
    33421 cgggcggatc tattttataa ccacgtctcg gacctcatcg gcagccgaat caccgcgagc
    33481 gggtcttctg agtttgtgaa cgatcccgga tccgccgaca tctatggggg cgaagccggc
    33541 atcgaggttc tggccaatcg ctggttaagc ggattcgcca attatgcata tgaggagatc
    33601 ggccagtcct tcaccggaac agtccgccgg ggcgcgccac gatcgaaggt gagcgcaggg
    33661 gtccgcaccg aatgggataa cggcctgagc ggagagctca gttattacta cgtgggcgcg
    33721 gccacttatc cgcttgcaca aagcttcacc caactcggca ctattccggg agctggcatc
    33781 acggtgcctg gaaaccaggt gggcagctat aacctcctca atctgcgtgc cggatatcga
    33841 ttctggcaac agaaggcggc ggccgggtat atgcgtgatg cggaggtggc gatctcggtc
    33901 ttcaacgcgc tcaatgacga acacaaggaa caccccctgg gcgacttgat cggccggcgg
    33961 gtgatgggtt ggctgacgct tcggttttaa cctgtgcccg acgacactcg ggaggatgca
    34021 atggcaccgg caacactgac tcattccatc ctggttgtgg acgacgatcc tgatattgcg
    34081 cttgggcttc aggatttcct cgaccacgac gggtatcaag tgaacgtcgc catgacctgc
    34141 gcggaagcgc tcgcccaagc ccacgcccat cactacaatg cggtattact cgatctgggc
    34201 ctgccggacg gagatggctc ttccgttctg ctcacgctcc accaacaaca gccgcaactg
    34261 ccggtgatca tccttacggc ttataccagc accgaccgca cagtcggctc gctgacacaa
    34321 ggtgccttcg cctacctgac aaaaccctac aatcgagatg aactacgcgc ggtcctgcaa
    34381 cgggcagtgg gcgtccaggc cctggccgtc aaggctgaac atgccgagca tgccctgcat
    34441 gagagcgaag cacggtttcg ttccctcgtc gaagcggcga ccgactccat cgtcctcgcc
    34501 gatcacaatg gtcatattct ttcctggaat cgcgcggctt cgcacctgtt cggatacacg
    34561 gatgaggaag tccgcggaca gtccctcagc atcctgatgc caccccggca tcgcgccgct
    34621 cacgaacggg ggctggcgcg ggtccgagac acgggggaat cccgcctcat cggccgcctc
    34681 gtcgaactcg aaggattgcg gaaggacggg agcgagtttc ctctggaact ctcactggcc
    34741 atgtggaaaa gcgacgaagc cgtgttttac agcggcatca tccgcgacat tacacaacga
    34801 cgccgcgccg aggaaattct tgaccgcctg cggcatctcc acgaggtcat cctcactcag
    34861 gccggcgaag gcatctatgg cctggatcgc gacggaatca cgacgtttgt gaatccgaca
    34921 gccgccgaac tactcggcta cgaaccgttc gaactgatcg accggccgat gcatggcctg
    34981 cttcatcatt ctcgatccga cggcagcccc tatccgtcag gtgagtgccc catctatgcc
    35041 gcattgcacg acggactggt gcatcgcgtc tcggccgacg ttttctggcg aaaggacggt
    35101 caccccgtgc ctgtggaata cgtcagtacg ccgatcatcg aaaagggacg cacagcaggc
    35161 gcggtcgtgg tgtttcgcga tatctccgaa cgcaaagagg ctgagcgcgc agtcgaggaa
    35221 agccaggagc ggtttcgtca actggcggaa catatccgag aggtgttctg gatcacgaat
    35281 ccagaaaaat cgcatgttgt gtatatcagc cccgggtatg aggaaatctg gggtcgctcc
    35341 tgcgatagtc tttacgccca tcccacgtcc tggctggatg ccattcaccc tgaagatcgg
    35401 cctcgaatcg aagaagccgc cataagccga caagcgttgg acgtgtacaa cgaaacctac
    35461 cgcatcctgc gtccggacgg atccatgcga tggatctggg atcgcgccta tccgatccgt
    35521 gacgcctcga atcaggtcta tcgcatcgtg gggttcgctg aggatattac cgagcagaaa
    35581 cggatcgagg cggaattgat cgctagcgaa cgacgctatc gggtcctctt cgacgacaac
    35641 ccgtctatgt atttcatggt cgatgccgtt ggcaccgtgc tctccgtcaa tcgcttcgga
    35701 gccgaacggt tgggctacga ggtgcaggat ctcgtcggga cctccgtcct caacgtgttc
    35761 catccggagg atcaacaggc cgttttacac aatctgtccg actgcctctc cgaagtggga
    35821 caaccgaagc gctgggaact tcgcaaagtc cgaaaagatg gccacgtgat ctgggtgaga
    35881 gaaaccgccc aggccgtgcg gggacacgaa caagcccccg tggtgctgat tgtctgcgag
    35941 gacatcaccg ccatgaaaga ggctgaaatc gcgcttcacg acagtgagga gttaaagaac
    36001 cagatcctgc acagcagcgc ggactgcatc aaggttctcg acctggaagg gcggctgcaa
    36061 tacatgaatg atgccggaca gacgttgctg gagatcaagg atcttggcac ctacaccaac
    36121 aaaccctggt cggaattttg ggagggagac gatcgggagg ctgccttagc cgcgctggag
    36181 gcagccaagg ccggggacat tggaaagttc gtcgggttct gccctaccac gactggacag
    36241 gcgaaatggt gggatgtgca ggtcactcct atgcttgaca cacaaggcta ttcccggcgt
    36301 ctcctggcga tttctcgcga tattactgcg tataaacagg tccaagaatc gctccacgcc
    36361 agcgaggaac ggttggaaca cgtcattcgc ggctcccacg acgggttctg ggacggccat
    36421 gtcttgcccg atcatccttg gtacgcgcct attacccccg tgtggtggtc tccccgcgtg
    36481 cgcgaaatgt tgggatacaa tgaagaagag tttccggaca ttctcgacag ctggatgtcc
    36541 cgattgcacc ctgaagatcg tgaagcagtc tttgagcggc tgaatgcctg catggaacaa
    36601 ggcgtctccc agtacgacgt cgagtaccgg ctcttgaaca agcaacatga gtatcaatgg
    36661 tttcatgcac gcgcggaggt ggtccagcgc gatgcacaag gacaggccgt caggatggcc
    36721 ggcgcattgc aagatatcac cgatcgcaaa cgaaccgagg cccgactgcg gctcagcgaa
    36781 gagcgcttgc gcatggccct gacctcatcg gatctcggca tctgggactg ggatgtgacc
    36841 tccgaccgtc tgtattggtc agaaggcgtc gaactgctat tcggcttggc gccagggtcc
    36901 tttcccggca cctataccga ctatattgga ttgatctatt tgttagatcg cggatctact
    36961 cttactcgcc tcgaactcag tcttcgtgat cagacttccg tccatattcg gcatcgcgtc
    37021 gtatggcccg atagctcgat acattggctg gcatggagcg gacggatcta tcggaatgcc
    37081 gacggagtcg caacgcgtgt actcggcatc gtgcacgata cgacaggacg catggacgaa
    37141 tgacctggcg acattcggcg acctcatacc gggcaggctg attcgacgag gacgcagatt
    37201 gtgacgtgtg cattcctaca acggacgtgt gacagcaggg catcaggacg cctttggaac
    37261 aggctatgct ggagcatggt tctcctcttg tggaccttgc tgatcgccag tcctgccctg
    37321 gcaactgacg tcatcattct caaatcatct gatatcgccg cctacaatca agccatcaat
    37381 ggcttcaaag ccgctatccc ggccggaatc aatctctccg aatacgactt acagggagac
    37441 cttgagaagg gtcggaaatt ggctcgaaaa atccgcgcat ccgatccgtc attggtcttc
    37501 gccgtcggat tgaaggcggc caaggcggcc caacttgaaa tcgtcgacat ccccgtcgtg
    37561 tactctatgg tattggatcc ggccaaatac ggtctcaacg ctcagaatat gaccggggtc
    37621 ctgctggaag ttcccgcaga acggcagcta gtcatgatcc gcaacctact gcctcaactc
    37681 aaacacatcg gcacgctgta tgacccagcc aagacctcga cgctgattga cgaagccaga
    37741 cgtctactga aacagagcgg aaccgaactg gctccgatgc aaatcagcag tgaacgggat
    37801 gtgcccggaa gcttgcgtgc cttactgcct tcggtcgacg cgctatggct cgttcccgat
    37861 tccacggtgc tgacggacga gtctctgcgc tttatcttaa atacggcact ggaagctcgg
    37921 gtaccggtga ttggcttctc acgcgagttc gcgcggagcg gggcgttatt gtgcctgtcc
    37981 gtcaactacg ccgacatcgg acggcaggcc ggacaactca cacgcaagct gctcgagggc
    38041 cagctctcgt taccgctaaa accctggcac cccgaccgca tcgaaaccag cttgaatctc
    38101 aaaacggcca aattcctcgg tatcgacatt cctcgtgaac tcgagcaaaa ggccgacgag
    38161 ctgtattgat gaaaggaccg tctgtgaaag atcccgccca tcttgccgcc ccgccgttcc
    38221 tcccgaacgg gctgaaacga ttcgtcagcc tgcgaaccaa gttcgtcgtg ttttttagtc
    38281 tgatcatcat cttcacgtgc tcaggtatga gttggtattt catccatagc aaacgcgtcg
    38341 cgatgaccga acgggtccag gacctcggca gcatcctggt gaagaacctc gctcacaatg
    38401 ttcggtacgg catcattctc gaagatcggg tcattctgga acaattcatc gacggggtgc
    38461 tcggagtgga tgaagtcgtc tacgcgcaga tcaccggcgc cgatggccag gtccttgccg
    38521 cgaagagcaa aggcaaattg aagacaccgc tcgggacggt gcgcgccgtc gatcagccgt
    38581 tttacccgtc cgctgcgatc gcggcatccc tgatcagaca tccgctcccg gaaccgactg
    38641 tgacacggct gcgactcatt ggcgaaagta gcctcccctt tgaagagcaa gacgccacgc
    38701 ttcgcgtatc aacggccggc atgcgagaag aaacgtttta cgattttgcg cttcccgtgc
    38761 tcaaacgcgc tgaaccgaga ctggaagcac tggcgcttca agaggaagag acgcacaaga
    38821 cccgcaccgc ggcgtcgacg gcgcctgcct ttggcgtcgt ccaaatcggc ctcactgagg
    38881 tacccatgca gcgcgaactg gcggaggtgc tacggacctt cctcctcctc actttgggca
    38941 ttattacggc cggtattctc tccaccaatc ttcttgcccg ccgcatcatt acgcccttgc
    39001 gcaatctcgc ggcgggagcc cgcaaagtcg gcgaaggcga tctctccacc tttgtcgtgc
    39061 cgaccacaca agacgaagtt ggccagctca ctgcgctctt caatgtgatg accaagtcgc
    39121 ttcaggaacg taatcaggcg atctctgcaa acctcgaaac catccgccgc cacgtcaccc
    39181 agttgacgac cctgaaccaa tccagcgcgg cgattacctc caccctcgat ctggatcggt
    39241 tgctctctac ggtgctgcag cttctgagcg aaaatctcgg cttcgccaga atggtcctgt
    39301 tcttgtggga tagcgagcgc ggtgtcgcca cggtaggaca aatgctgggc atgccacccg
    39361 aggctgaaga agccgcacgt cgtctggtca tgcccgtgca tgaggacggc gggttcgccg
    39421 cggaaatcct cctccacggg aaacccgtcc tggtgccgaa tatcgagacc gtcgccgacc
    39481 gcatctctcc cgccgtcttg ccttggcttc gccaggtcgg attgtcgtca tttgtcgccg
    39541 cccctctccg cagtcagcaa cgcattctcg gatatctcgg ggcggatcgc ggcgcacagc
    39601 cttgcaccca ggaagatctc gatctgctgg tcaccatcgc cagccatgtg gcggtcgcgg
    39661 tggacaacgc gcgggcgtat accgaactgg ccaccttgac ggaacatctc gaacgacgcg
    39721 tggaggaacg gacgcatgaa ttgcaatccg tcaacgagcg ccttcaggac cacgatcagc
    39781 gacgctcgaa gtttgtttcc gttgcatctc atgaattgcg tacaccgatg acgtccatca
    39841 aagggttcgt cgaaaacatg ctggatggat tgaccggaca actgtccgaa cggcaagagc
    39901 actatctgca acgcgtgaaa cataacgtgg atcggctgac gaggatcatc aatcaattgc
    39961 tggactggtc ccgcctggat gtcggacgca tcgacatcaa acccgagtcg ttgtctatcg
    40021 atgcgtttgt ccgtgatgtc gtggagagct ttcagaccct ggcggcagaa aagtccatta
    40081 cgttagacgt cctgccgtgt gagcaacccc ttgtcgtcta tgctgatcga gacaagctgg
    40141 aacagatttt gtggaatctc gtcggcaacg ccatcaagtt cactccgcat gccggtcacg
    40201 tctccgtgca atgcactgcc catgatacac attcggtcca aatcaccgtt gccgacaccg
    40261 ggtgtggaat tgcccccgac gagttaccgc tggtgtttaa cgaattttcc aaagtggaat
    40321 cggccatgcc gacgtcgcaa ggcgcacagc tcggcctctt tattacgaaa agcctcgtca
    40381 ccctgcacgg cggtcaaatg tgggtagaaa gccgattggg ggcgggaacg cagttctcct
    40441 tcaccttgcc gctctccgcc acgcaaccgg cgcaaccgta gattcacgct tcactcgaag
    40501 cgacgtctct tccctgtatc cgttccgata atagccgcat tgttttgaac agccctgact
    40561 ggactgttca gaatgattca tctgtcggct tgtcttgctt cgccggagaa tcaatgagtt
    40621 gttcgtgcct ctcaggagcg tatcagcatg gcgtttgcgg catgggtatt gcggacatca
    40681 accaacacgg gatgtttcac cagacagcgt ggccccaccg tgcataccgc cgtgctcatt
    40741 gtcgatgacg atcgggatat tcgcgaatcc ctcaccgaca tgctgcggca tgaaggttat
    40801 ctcgtcgaga gcgcggggtc agggaatgag gccctgtctc atgccaaaca gcggcagtac
    40861 ggcgcggcca ttctcgacat ccagctgcct gacctcaacg gactctcggt gctgaaagtg
    40921 ctgatggagt tggacgcctc gctccccgtg attatcctga ccgggaacgc aacctccgag
    40981 aataccattg gctcgctcgc caagggcgcg tttgcctacc tgactaagcc gtacaacgcg
    41041 caggagctga aagccgtcat tcgtcgagcg gtttcagtga aagggctcgc ggtacgcgcc
    41101 gaacatgtcg agcaagccct gcatgccagc gaggagcgat tccgcgcgct ggtggaatcg
    41161 gcaaccgacg ccatcgtctt ggctgaccac tacggccata tcatttggtg gaatggggcg
    41221 gccgaacgga tgttcggata ttccaaacgt gaggcgctgg gacagtccct cgccatgctc
    41281 atgccggaac gcttccgttc ggcccatgag acaggcatca tgcgcctgac cacagggtcg
    41341 gctgcgaaac tgatcgggaa aaccgtcgaa ctggtaggac tgaccaaagc cggggatgaa
    41401 tttcccatcg aactgtcctt ggcctcctgg cgtgccaagg agggcgcgtt cttcagcggc
    41461 atcatccgca acattacgcg gcgcaaaaag gcggaagaat ccgtcgtccg gctcagccac
    41521 cagaacgcct tgattctcga cgccgcaggg gaaggaattt tcggccttga ccttgaggga
    41581 cgcacgacct tcgtgaacgc cacggcggca cgaatgctgg agtggagtgc ggcagaattg
    41641 atcggcaaac cccttgcccc actcctgtat agacttcatg acgaaggagc cgagtatgtc
    41701 caggatccct tatgtctttc cgctgcagta cgcgacggag cggtgcaccg tgtacaaaac
    41761 gatgtgttca ccagcaaaag cggggtgtca ttcccggtcc aatacgtaac cagtccgatc
    41821 cgtgaacagg atcgaccagt gggcgtcgtg gtggtgtttc aagatatcac cgcgcggaag
    41881 cagctggaat gtttgcaaca ggcacaactc tccatcagcc atatcctcgc tcagaccagc
    41941 acgctcgaag aagccgtccc ccaactgctc cgcgtgatcg gagaaatggg accgtgggag
    42001 atgacgatct tctggcacaa agaaccgatg aacgaaagac tggtctgtga aggcacgtgg
    42061 atgcgatcct cctgccgctg ggatgaattc gccacgatct gccggaatag cgaattccct
    42121 ccggggatgg attttccggg ggtcgtctgg agcacgaaac tgccactgtg gattcccgat
    42181 gcgttgacag acgcccgctt cacccgcgcg ccgaccgccg ccaggctcgg aatacacggg
    42241 gcctgcctca tccccatccg aaccgggacc gtcatccatg gcgtactgga actgtatgca
    42301 gacaagcctc gcctgcctga tcgccaactc attcacatct tgaccgatac cggcatgaaa
    42361 atcggacagt ttatcgaccg cgcgcaagcc gggtcggcat tacgcgcgac ccatcgaatg
    42421 acgcagaatt tgctggccag cctgccaggc gccatcttcc tttgcgcccg tgacttcaag
    42481 atccaatatg ccaataccct ggcgcatcac tacttcgccg tcgggggagc gtccttagtc
    42541 gggaggccgc tgttcgaatg cctcgcgctc agtgaggccg cgacgcaaca attgatcaaa
    42601 gaatgggctg cgctcaatgc cgactcaccg catcaggccc ccgaacgcga atgcgaagtc
    42661 gcttcacgac tgtatcggta ccgcttcttc ccggtcgcca ctccggaaag cgctcagtat
    42721 caggtaggca tcgtgctgtg ggacgtcacc gacgacaaac atctgcagga tcaactgatt
    42781 caatcggaga agcttaccag tctgggcaca atggtctcgg ggatggcgca cgagatcaat
    42841 aatccggctc aagccatact cagcatggcc gaactgattc aggaagaaaa agacccggcg
    42901 gtgatcaagg aatttgccgc cgatatcgtc ggctacgcac gccacgtctc caatgtcgtg
    42961 cgggatttcg ccggatacgc tcgttcggct ggccgggacg gcgaaacgga aatcgatgtg
    43021 gcggagcgcc tcatggaagc cgtcaagatg gcccgccgag gtccgcattt cggctacgtc
    43081 gatgtcgtca cgcgcttcga cgcccccact tttctgcgcg cccgcaagag cgaactcgat
    43141 caggtcttcg tcaacttgat caacaatgcc acgcaagcca tggacgggaa aggccgcctg
    43201 accttaggcg cggctcaaga cggtgcgtgg attgatgtga cgatttcgga taccggcccg
    43261 ggcattcccg ctgccgtgcg gcctcgcatc tttgatccat tttttactac gaaggcgccg
    43321 ggaaagggga cggggctggg tctcagcatc gtgcataaga tcgtgactcg gcatgcaggg
    43381 acgattacgg tggacagcac cgaaggggaa ggcaccacgt ttaggctgcg ttttccggcc
    43441 ttgttgcagt aaaggggaaa caagcacggg tcgacgacga gcccgcggag ggatttacgc
    43501 gcgggaacga gaagagtagg cccgcttaaa gacggaccgc aatccgaagt aggcgaatga
    43561 atccttcaga ttggaataga gacgtttaaa ggcgcccatg tcgggattgg tcacatactc
    43621 gagcgtgagc acaatccgct cttcctgctc gccgagcggc gtcacggcat gccagagctt
    43681 gtctccgttg aagatcacca gatcgccggg cgctgtggcc aattccatat gtaccggctg
    43741 tttacccggc acatctttaa acagatcaca gactaagcgg cattgtttgg actgatccag
    43801 caaccccagc agaatcgtgt accgcgcgcc tttatagtaa gaggtatcgt agtggtatcc
    43861 gatgtggtcg ccggcttccg tgtagtaata caaggcacag gaatgcggat cgttgtcggg
    43921 gcagagtaga agattgaccc tggtcaactg attgagcatg gctcgaaacg cgtctgaacg
    43981 atacaggtcc atgaactgcg gggcctgctc cctcaccgta tagtagctga cactgccgcc
    44041 cttcttatgt cccggaatgt aattgcgatt caacccggat ttgagcacct gcgcctgtga
    44101 cgccagctcg gcctcgacaa actcgcgcgg cagaaattgg ggaatataca gaaactcgtt
    44161 ctgctcccaa tagtcgcgct ccaaccggtc gagatccagg gccgaaatgg cccgctcaac
    44221 cgcctctgtt acgctgcttg cacaggcctg cgtcatgcgt ccctcactga gtccggattc
    44281 atcatggttc cactgaggac atcgtcttcc gatgaacaaa acgccactta aaaaaaagca
    44341 agttgcttgc aggatggtca aaaagtccgt ccagtgaggc cgcagcgagc agacaaccga
    44401 ggcgtaccct cgcggtacgt tgaggttgcc tgcgatgcga gaacgaagct ggctgatttt
    44461 tcaccatcct gctagggtcg gctcagcacc ggcgccctga cgatttctac atcggccggg
    44521 gccttgaaat caaataggtc gtccttcaat ccgctgttcg gcttgagttc tgagaattca
    44581 aaggtggcga cgttgccact gacctcatgc agtgcaatgg tcttgaggaa gtaggtttta
    44641 ggctgcacct cgatcacgat tttttgaatc gctcgttccg gttcggcacg tccctgtttc
    44701 ggagtcagcg ataccaggag aatacccccg gcgccccgct ccttattcgg catcggttcg
    44761 atatcgaact cctcatccag cttggcaaca ccctgcaaga gctgcagcgg cgcttgtgac
    44821 gcggccatat aggtgagctt accgaccagg acctgcttat gctcgggcac atacatcttc
    44881 acatcgtctt tgttgacgta gatttcttcc gtggccggtt caatatagtc ccaccgcaac
    44941 ttgccgggct tcttgatgta aaagtgaccg gtcgaaatca ccggcgtgga aaatccttca
    45001 atcctggttt tttgcgtgaa tgacgcctgc aaatccttgg tcttttcata tcgcgactga
    45061 atgttcttca ccacctcctg cacttcgtgg agcgactgga ggtcgacggc cggctcgtcc
    45121 ggcttcacga gttgagccgc agccggaatg gcgctgacca ctaacaccgc aatgagtaac
    45181 cctgttcgca tcatgcctca tctccaccaa ccgggcctcg acgtccgagc acctcgcgac
    45241 gtccatcccg tccggccgcg cccacaacgc cttccgcctc catctgttcg atcatgcgcg
    45301 ctgcccgggg atagcccacc cgcaagcgcc gctggatcaa cgaggccgaa gcctggcctg
    45361 tcgagaggac gaggtccttc gcttgttcat acacttcgtc tttcgcctgc tcctcttccg
    45421 cttcctcgat cttgagcgat tgcagttcgc gacaatacga gggcaaggcc tgcttcttta
    45481 caaactcgac cactcgccgc acatcgtcgt ccgagacaaa cgatccgtgg atacgcatca
    45541 atttcccggt tcccgacgcg aggtacaaca tatctccgcg gccgagcagc gcttccgcgc
    45601 cgttcgcgtc caggatcgtg cgggagtcgg ttttggacga gacttgaaac gcgatgcggg
    45661 ccgggaaatt ggccttgatg agaccggtca gcacatcgac cgacggccgt tgtgtcgcca
    45721 gtaccaggtg aatgcctgag gcgcgcgcca tctgagccag tctggcaatc ttgtcttcca
    45781 catctttcgg ggccaccatc atgagatcgg ccaactcgtc gatcatgacc atgatatagg
    45841 gcaagggctc aggcaggctc ggcttgaccg aatcggtcgg cccgttgtcg ccggctggct
    45901 ctgcatcttc ccccttggaa agccgttctt cttcggacag aaacgtcaat tccacctgtt
    45961 cggctttccc ggattgccag acatcggaca cggccccatg gagctctgaa atccgccgat
    46021 tataggcatc gatgctgcgc acgccggctt cagccagcaa cttgtaccgc cgctccattt
    46081 cctgaaccac ccatcccagg ccacgcgcag cggacttggg atcggtgatc acgggacgca
    46141 gcaaatgcgg aatcccgtcg taactctgga actccagcat tttaggatcg atgaggagca
    46201 gcttgacttc atccggccgc gcgctgaaca gaatgctgag caacatcgta ttgagaccga
    46261 cgctcttgcc ggcaccggtg gcccccgcga ccagcagatg cggcatggtc ttcagatcgg
    46321 cacagactgc gccgccgaaa atgtctttgc cgagcgccag actcaatttc gagcgggagc
    46381 gtgaaaaagc gtcgctggtc acgacctcct tcatggacac catttcccgg ttcgggttcg
    46441 gcacttcaat gccgacgacg gacttgccag gcaagggggc cacgatgcgc aaactgatcg
    46501 ccttgagcgc aagggccagg tcatcggcca ggttcacgat gcgcgcgacc ttggtgccgg
    46561 gcgccggctc gaactcatac atggtgacga cgggccctgg acgcacttcg gtgacgcgtc
    46621 cctcgatcgc aaaactcttc aaggccttgg tcaggatctc cgattgaagt ttcaattcat
    46681 cgtcgctgag gcgagcgata ggaccggacg gatcactaag taattcttgc ggatccggca
    46741 acacatatcc gtcggacacg gatggactcg tcgccaccgc cgcagccggt tcgtcttcag
    46801 gcgtagcacg cttctcgact ttcatcggcg gctgaatttt gggaggaatc atggggaccg
    46861 cgatttgctc aacagcctcg gccaccacct gcacttcgcg gtcgagttcc ggttcttcca
    46921 tctcacgtgc ggggcgtgcg actttcacac gagcccgctt cggtggcgcc atcggctctt
    46981 cctgcttgac cggccactcc ggcatgagcc ccgtcatccg ctcacgggcg gcgatccacc
    47041 agtccggaat cctctgcagc aatgccgtta gcgacacagg caccgtaaag agcagggcca
    47101 ccatcaaccc cgtgagcacc acaatatgcg cgcccgtcgt ggcgaaataa ctgcgcactc
    47161 catcggccaa cacctggccg atgatcccgc cggctaagcc gcgattgacc catccgctgg
    47221 aaatcgtagg caccgctgtg acttcgaggt gcaagagcgc gctcaaaaac accatggccg
    47281 ccagtccgct gcccgcattc ctgagtcgca tggtgagggg gatgggagtg aaacagcggg
    47341 caccgagaag cccgagcaga atcggaaaga ggtaggcggc cccaccgacc atgaagaaac
    47401 atgcggccgc cgacagcgct ccgaccgacc cgatcatgtt tttgggctga ttgccggctg
    47461 ctccggatgc cccaatcgat ttggcgtcgc cgggaacaaa cgacaccaga ctgagcagga
    47521 tcaagagacc gactgcgatc aggagaaccc cgatcacttc gcgcttcaca tgagaggaac
    47581 gggaaggggc tgagcgggcg tcaccgcgct ttgccgtggt ggttacaccc atgcggcgga
    47641 tcgtagcaca gggaaaatac cttttcaaac aaagcggcaa tgttgcgcat ggctatcacg
    47701 atgctcccat ttccgtcgag accgtcgtga tcaagccgac tcatcatcgt cgaccgccgt
    47761 agcgagggcg cgatagtcat cgagggtcag cgtctccgcg cgagcctgca acggcacacc
    47821 aacggcttgc atcgcccggg aaatccgctc gaccggataa ccctcgtcgc gcaacgaatt
    47881 caccaacgtc ttccgccgat gagcgaaggc ggcccgcacc aaccgccgga accgctcata
    47941 ccggtccgga tcgacgccgt cctgggtctt gagcttgaga tgtacgactg cggatccaac
    48001 agttggacga gggcggaaac aattcgccga cacgcgaaac gccacctcca cctctgccgc
    48061 ctcttgcgtc aggaccgaca agacaccata gtcctcgctg ttcggtttcg ctgccagcct
    48121 gagcgccact tccgtttgca gcatgaggac cagacgatcg agatgggcac gggcatcgag
    48181 taacgcaaac aggatcggcg tggacacata atacggcagg ttggagacca ccaccgtccc
    48241 cggcggcaac gtgtcgaagg gaaattccag cgcatcgccg atacgaaggt caaggttccg
    48301 gcaatgactg agcgtctcct gtaattgggg ctgcagttgc ggatcgatct cgactgcaat
    48361 gacgcgtccg gcttcggcgc acaacccggc cgtcagggcg ccacgcccgg gtccgatttc
    48421 caaaaccgtg tcgtcgggac gaagcgcggc cagggatacg attttgcgaa taatgttcgg
    48481 atcgatgagg aaattctgac caagccgttt cagggcgggg ggaaaggaag cagccatgat
    48541 ttcacgcggc tttctatccg gcgttgggtg gcaccgccgc tcgcaggcgt ttggccaatg
    48601 tcacgagata ggaccggtaa gattcgacct cgtcgctgaa ctcttcgatc agatcgttgg
    48661 taaacgacat cccgggcttc ttccgggaca ggccatccgc ctcagcctgt ccggcatgct
    48721 gctgaagcaa cgccaccgtg cgaatcttcc actggcccac acgttctgtg cccagggtgg
    48781 tgttgaagtc ctggatggtc cgcttttcga ttccgtccaa ctccttcacc tgttggtcaa
    48841 tgatggttgc tgcggaagag cctgcgtctg acatggagat accgcctctt tcctatcggg
    48901 acaatgaatg aacaggggac caggatttgg ccaaacgagc cgccaccttc actgcctcga
    48961 gcagacttcc atgctcggcg acccctttgc ccgcaatatc gtacgccgtt ccatggtcga
    49021 ccgaggtgcg gataatcggc aggcccaccg tcaaattcac acaggtgccg aaggccacca
    49081 acttgagggg gattaaacct tgatcgtggt acatcgccac aaccccatca taatcgccgc
    49141 gggcggcttt gccgaacagg gtatcggcag gcagtggatc gctggcgttg atcccggtcg
    49201 cccgggccaa tttgatggct ggcgcaatac tggtctgctc ctcatttccg aataagccgt
    49261 gttcacctgc atgaggattc aacgccgcaa cgccgatctt cgggcgtgcg atgccgaaat
    49321 acttcgtcag gccaagatgg gccagacgaa tggctttggc aatgcgctgc gtggtcagga
    49381 gcggagacag ggcatggatt gcgacatggg tcgtggtgaa cataattttt aagggcccgc
    49441 ccacgatcat cattccaaat tctttcgtct tcgtcagatc cgccagcagt tccgtgtgcc
    49501 ccgggtaatg aaagccggcc atgttcatcg cttctttatt gatgggcgca gtgacgattc
    49561 cgcccacact ccccgcctgc gccaattcga cggcttctct gataaatgcg atggaggccg
    49621 ccccggtcac tgccgacgcc acccccaggc gaaatttcgg cagcggacgt tccaacggat
    49681 cggcgacagc gacctgaccg ggcttcactc gtgcaccgct cgccggatca aacgtcacca
    49741 cgtccaacgg caaatccaac cacttgatcg tgcgttccat gaccgggcgg gagccgatga
    49801 ccaccggctg acagagccgc gtgagcgcct tgtcggccaa ggccttcgca atgacctcgg
    49861 ggccaatgcc ggccgggtcg cccatcgtga gacccaacac ggggcggagc gagtgttgtg
    49921 aacgcttacg agccatgggt gtacaagaat aacgtgtacc caaggtacag cagcgcgctg
    49981 ccgctgagca accaggggcg ccagtgccct gaccacaggg cctgtaacag gctcatgctc
    50041 atcgccacga ccgcaaggac catcgtcgcc agtgccgttg tacccaaggt ccattcggtc
    50101 ccaagcaatc cgacggagac ggggatcgat ccctggaaca ccatcgcacc ggtcacgttc
    50161 cccaccgcca gccgatcctt tttccggtac aaccacaaaa agctattgga catctcaggc
    50221 aattccgtag ccagcggagc gatcaacaat gcgaggatga gcggcgagac ctggagttgg
    50281 gcagaaatgg agttggcagc cgtcacaaac agatgagcgc ctccaaccaa ccccagcaac
    50341 ccgacgatgc cttgcgcccc gatcaccaga taggagggct tagcggagcg ccgcgcgaag
    50401 agcagcggct cgagttcgtc tccgccctca ctttcttcgt cctcggcaga aaacttgagc
    50461 ttcatgtaat agacgtacat ggccagcagg acagccgcca ccgcgacatg caagacccgg
    50521 gagggaatca tcgcgcacgt gagcgccagg acatagctga cgagaaagaa gctgatatcg
    50581 acccgcacct cgccataatt cagcttgaac gttgctgttc gcttccccaa cttggcatag
    50641 agcaccagca ggagcgccag aatcggcaag actaatgtgc tcagcatgaa tggcgcccca
    50701 agaatcgctc ccagacccac ttccatctgt tcgcggccag ccccgaaaaa aatggcaatg
    50761 attggaatcg atgtttcagg caaggtcgtc ccgacggcag cgaacacact cccgacagcg
    50821 ccttcggaga tattcaggcg ttttccgagc cactcgatgc cgttcgtgaa gagatgacac
    50881 ccggcaaggg tgatgacgac ggaggccaca aacattccca catacaggag aactgtcatc
    50941 ggcgcctccg cgggatcaga aaaaagggga aggagagaac agccacgatc tggtgaatca
    51001 cgcgcgccct tttcttctcg ggcgggtgcc tagtgtctgc cgatacacca tcagggcttc
    51061 gtcgagaatg tctttgacgg gacgaccact ccgttctgcc acgcgtttac aatcgtcata
    51121 ttccggagcg gctttgctga gccccggccg aatatcagcg agttttatcc gcacatcctg
    51181 tccgttgact cgcaccgaag caaattggcg cggcaacaca cggcgttgca cctcgcgaat
    51241 ccgcacaccg agagccgtcg tctcggcaaa gagcacagcc aggaccgcct ctgtgtgttc
    51301 ccgcggcgca aggacggaca ggacattccc cggccggccc ttcttcatga tcaccggcgc
    51361 cagggtcgca tccacggcgc cggcggcaaa tacgcgatca aacaccgtgt cgtacacttg
    51421 cgggttcaca tcatccagat ttgtctccag ctcgacgatg gtttccatcg ccccgctctc
    51481 ggacgcctcg tcaccgacga acacgcgcaa cacattcgcc cactgtgccg ggtcggcagt
    51541 ccccgcccca tatcccacct ggcgtacctg catggaaggc aggcagccga aatcggtggt
    51601 cacggttttg agcaaggcca tcccggtcgg tgtcgtcagc tcccgttcag gccccttggc
    51661 ataaatcggc acgccgaccg cgagggccgc cacggctggt cccggcacgg gcaacgcgcc
    51721 gtgcgccgac tgcagcatgc cggacccgac attgatcgct gaggccgtta cacgccggat
    51781 atcgagaaga tgcaggccca ggatcccacc gacgacatcc acaaacgaat cgatcacgcc
    51841 cacttcatga aaatggacat gcgacggctc aacaccgtgg gccttccctt cggcgtctgc
    51901 cagcacatcg aataccgcct gacttcgttc tttcaccgct ggcgggaggc cgctcctgcg
    51961 aagaatcttg gcaatttgtg acagggttaa cggcgcgcga aagcctttgt cgatcaggac
    52021 atcaaccttg gtcgccgtga tggctccgcg ctcaactcgc ttacgcgtca gccgatagcc
    52081 gtcgatcttc agcgaagcga ggcctcgcac aagatctttg aacggcagcc ccgcatcgac
    52141 caacgcgccc aatgtcatat cgccgctaat gccggagaaa caatcgaaat gcagatgcct
    52201 cgccacgtcg ctcctacaat tgactctttc gcgcaaacga gcggcatctt accggagccg
    52261 cacccagaca gcaatcattc cgctcgttcg ttgacagccc tgccatgctg tgttatcccc
    52321 aatcaagaga cgcattccat cggccaccag ccaccaccac ctgcgacacc gacacccatg
    52381 acgaactcaa caccagctcc ccgggtcagc ctcaaacgcg catcgacagg aaggactttc
    52441 ggcctgctgc ttctgctcag cggcttttgc ttactgggag acccaagtct gcttctcgcc
    52501 aaaaccaaag gcaaaagcag tgtcccgcgc cccgagccgg acctaaaaat tctttcgctg
    52561 caagctgcgc ccatgccgta tcgaccgcag gagggtcctt tccatttcat cgccacggtg
    52621 caactgccga aggaagtcga tgaacatctc atgttggaag tctccgccct cgtcacctct
    52681 tcctctatga cctcgctgcg ctttctctcg attcgacagc cggtgaatga acatgtccag
    52741 accacgccaa gcgccaatgg cgatacaccc caaaaacatg tgcaggtcga cctcgaatgg
    52801 gacgggctgg atcacaacaa acaacagatc ccgatcggat cgtatgagta tgaagtgcgg
    52861 gtcaagctgt tgagtaacgg ggagaagggc cagcgcaccc aaatgctgtc atggcccaaa
    52921 cgcggcaaga ttgtggtcaa acactagacg agcacgaggc ttcgatacga caccccgcct
    52981 ctactgacgc tttgcccttt caggcttagg actatccatc tcactcacca tgttgatgcg
    53041 gtgggccagg cagccggcgc cgaacccgtt atcgatattc atcaccccaa cccccgccgc
    53101 gcaagaattc agcatcgtca gtaacgcggc caggccgccg aaatgtgcgc catatccacg
    53161 actcgttggc accgcgatga cgggctgccg tactaatcca ccgacgacgc tcggaagcac
    53221 cccgtccatc ccggccgcca cgatgatcgc ccgcgcgtca tgtaaccggt cttgttgacc
    53281 gagcaaccga tgcaaccccg cgacaccgac atcgtacaag gtgtcagtct tgctgcccat
    53341 gatatcggcc gtcacacgtg cctcttcggc aacgggaata tcggcggtgc cggctgtgac
    53401 gatgagcaca gaccctcgac gcaccagctt gggcggcaca atggccacca ctcgcgcggc
    53461 ctcatgatat gtcgcccgct tgctcatgcg gagcaatgcg cgcgcgacgg caggttccac
    53521 ccgcgtcgcg agcaacgaat tatttttcag caacagtgtc ttggcgatag ccaccacctg
    53581 cgccacagtt ttcccttcgc aaaagatgac ttccggaaaa ccctgccgca gagcacggtg
    53641 gtgatcgagc gatgcaaatc ctaaattctc gtacggcaac gtgcgtaacc gatgtagcgc
    53701 atccggcacc gccacggcgc cctgctgaac ctccatgagc aacgcccgca actgatcttg
    53761 attcatgaga gggccttctc ttccttcgct tcgcgttcca tcaagtcacc gactgcctgg
    53821 cggcagggtt tgtcggcgaa gagaaccgca ttgacctcct gcacaatcgg catatccact
    53881 ccgcaccgtt gcgccagccc caatgccgcc ttggccgtac gtacgccttc ggcgacggcc
    53941 tgcatgctgg ccagaattcc ttccaaccgt tcacccttgc ctaaccgtac cccgaccgaa
    54001 tggttccgac tcaacgggcc ggtacaggtc aggatgagat ctccaacccc ggacaatccg
    54061 taaaacgtcc gcgggtctgc gcccatcgcc atgccaagcc gaatcatttc ggccaacccg
    54121 cgcgtgatca aggctgcacg ggcgttatgg ccgagttcca gcccgtccac cacaccggca
    54181 gccagcgcca tcacattttt caacgatccg ccgagctgga ccccgatcag atcgtcatct
    54241 gcgtagaccc gaaacgtcgg cgtcatgaag agcgcctgga tggctttgac ggctccggcg
    54301 tcctggccgg cgaggcagag cgccgtcggt tttccctggc tgacttcgct ggcgaaactg
    54361 ggaccagaca agaccatcaa tgaatgtcgc atatggtcag gcaggacatc ctgcatcacc
    54421 tgcgtcatca gttcgagcgt cgtttcttcg atgcctttgg tcgcgctcac gaatggaatc
    54481 gactgtggca ggagagggcc aagccggctc agaaccagtc gcgccacatg cgaaggcacc
    54541 gcgaagatga cacaatcagc cccgatcagg gcgtcggaca agtggctggt ggcggttaag
    54601 gtagccggca gccgcactcc cggcaaaaac acgacgtttt cacgtcgttg gtcaatggcc
    54661 tgcacgacct ccggttcatg cgcccataca cacacggaga tctgttgctc ggccaaatgc
    54721 cgggccaatg cggtgcccca ggcgccagcg ccgatgactg ctacacgttg actcgatgat
    54781 cgcgtcatgg acgcggatta taggaagggg tctggaaggg tgtcaacgaa cgcatccggc
    54841 acattcgcat ccacactgga attccgtgcg cccacacggt aggctgcggg tccacgagga
    54901 gcctgagcca tgaaaccttg tccagcctgc ggacgcgccc tgccagaaat caatcgctac
    54961 tgcacctact gtgggaccgg cgtggccggc gacacggcac aaaaggcaat gccgcaagct
    55021 tctgaggcaa ccagagacca gctcaatctc cacatcctgt atggcatggt cacggtgttg
    55081 gtcgtgtctg tcatcatgcc gccctgggaa acgccgccct cgcaaccggc agcctttctc
    55141 ggctttcact tcatcctttc gccgccacaa cccgatgcca tcgtcagccg tttgttgctc
    55201 acgattgaac tcacgacgac ggcgattgcg gggctgtacc tatcgtttct tttccgatcg
    55261 aaggggtaac ggtgaggcac tcaggcaggc gggagagtgc tgtcagtcca gtgcaagagt
    55321 caggcatttg gcagcaccgc ctgacttcat gaactcatcc agctccacat catgggtgcg
    55381 atagccgcgg gattccagga gccgcatcgt gcggggacag ccggccggaa tgacgatacg
    55441 cttgccgacg cagaccgcat tgcaggcaaa ccgaatcgct tcgtcttccg gtacgacaag
    55501 ccgctgttcc tcagggatcc gttgcgcgat cgcggccagg ccataggcat cgaaggcgga
    55561 aggaaagtac aacagctctc cgccgctgag cggacaaaag caggtatcca ggtggtagaa
    55621 ccggccgtcg atgagttcga gcggaatgat ctcacgctga aaaatttcgc tcagcttcgg
    55681 aaacgaccgg atatccgatc gctggcgata tccgccgaac catgtgtccg gaaatcccaa
    55741 gagatcgccg gcgccttcaa aatagagcga ttcctcgagc gtcagcacct catacccatg
    55801 ctcgcggaac cattgcgcga agtacacctc ttcacgccgg cgttcgggat aacgaaaccg
    55861 gctgatcaca acccggcgac tcgccaccac cccggcattg gccgtaaaga cgagatccgg
    55921 aaggccggga accggctgca ttcgctcgac gcccactccc acatcctgct ccaggacgtg
    55981 catcagcgtc tgccattggc ccaccgcgcg agaaggaacc accgcattct cgcgtcgcat
    56041 ccagggattg atttcgtaat cgatttggaa atattcgggc ggacacacca gcagccggct
    56101 catagacgcc acccgagttc acgcgccagc tccttgagaa acgaggcggc gtccatcacg
    56161 agaccgacgg cttgaaaact gccccggtcc gccagttttg tcggcacgga aggattaaca
    56221 tcgacacaca cggtagggac ggaggcgggc aacaaattgc cggtcgcaat cgcgtgcaac
    56281 gtggaggcca ctaatagcgc aaggccgacg ccctgcactt ccgcgcgcat cgccccctga
    56341 gcctgcatgg aatccgtcac cacgccgggc aatggcccgt cgtctcgaat cgtgccggcc
    56401 atcaccatgt tgacgtcctg gcgcacgcag gcggccatga tgccttccgt aatcacaccg
    56461 gaacgcaccg cttcatggat actgccgatc gcgcgaatcc ggttgatcgt ccgcaaatga
    56521 tgctcatgtc catgcggaac ggaacgtcca gcagtcaatc catatccgag agacgtgccg
    56581 tataacgcgg cttccatatc gtgcgcggcc aacgcattgc cgcagaacaa gacatggata
    56641 aatccggctt cgatcaacca ggtcagcgct tcccggcctc cggcatggac aattgccggt
    56701 ccgcccgcaa gcagcacctt ggtgccggtc tgcccctgcc gatagccggc gcgtaatttc
    56761 agcatgcgtt gcgcgatatc ggcgatgacc ggctgatgcg gccgctctga ggacaccaca
    56821 gattccatga acccgaacac atcccgttcg cggggacggg ccagcggcgt caccctgatg
    56881 ccttctctcc ccgtcacgat caagtccccg gctttcaccg atcccatggg cagcgttctg
    56941 gcccgagcct ttgccgggtc gacacaaatg ccgagatcca tctccatgcc ctcgacctca
    57001 acccactcgc catcaaggcg gatctgggtc ggcaaatgcg tcgtggcata gaactcgtcc
    57061 gggaatatcc ccgccgccgg agccggctcg aaacggcact cggtgtcccg ttcaaccgcg
    57121 gcgccgtggg gttgaatggc ttggagaatc tcggccaaca gccggctgga atgggcgcgc
    57181 acgacaatcc gcgcctgcga gggcgcatct ctcgtcgccc caatgttcac atcctgcaaa
    57241 tcgaacgtgc cgcccatcat gaggatcgtg tccagcacct tggccaggat caacgaatcg
    57301 atgatgtggc cttggagaaa taccgtttcc tgcagtgcag tcatgacgga tctcctgaac
    57361 gctctccggc agtggcagcg gtatcgaccc tgcgtaacaa ccgcgtacca tgattctacc
    57421 attagtcagg aaggatggcc cgcactacgc atttgtcttc acgatctctc gtagcacgct
    57481 cgtggcatag gaaccggggg gaagccagaa cgagagggtc agcaccgacc cctccagcga
    57541 ccagaccaga tcattgagac gcacgcgcag ggctcgccgt tcaccgcgaa atccgcactc
    57601 ggctccggct ttcgagagca cttccggcgt ggttcccagt tcagcgatga ccgctcgctc
    57661 aatctcgccc ggctcaccgg tagcccaggg tgcgcgcgaa ccgaagagtg gtcccgtcgg
    57721 gctgatttcg aatcgatccg cccgcagctg ctcgacctcc ggctgctcca caggaaagca
    57781 ggcgccgttg tcggacttca tggcccaatc accgagcagc acccggtcaa tactgtcgat
    57841 tcgcttcgcc acaatgtgat tgaacacata cgactgatag gcattcatga accagatgcg
    57901 cttggcgcga ggcatcttgt tgcggcgggc cgcatcctgc agcaattcgg cacccagctg
    57961 aaagttcgtc cccgagcgtc cttgccgttg cgggccgaaa tagttgggca caccgcggcg
    58021 caccaactcc tcgaatagac ggcctaacaa ttcctcactt ccctcgcgaa catcccgcac
    58081 gaccaaacgg aactgattgc cggcatggtg ccctttacgc aatcgattgc gatggcgccc
    58141 caatacctcg acgctcagga gccgttcgtc ggtcggtaac gccgcgaccg cttccgcctt
    58201 cacaccctgt aaggacaaca tctgcgtcgt cacggcctgc gcgtccttca gccctgccac
    58261 gccgatcgtc tgcgccttca catgcaggtg ggacgagagt cgcagcacaa gatccggggt
    58321 ggacagccct cgcttggtga ttttgatgta caagtgctcg ccctctccgc aggggagata
    58381 cagggggcgc tcatccacac aaaagtcttc cggtgtactg cgaatgcgtc cgccgagcgc
    58441 agggacagac gcggtcaaat agggtaccgt atcatcgagc cacgagggag tcggcatgag
    58501 tttcctttat gattcctgaa agattacact tcatgtcatt tggttaggca cggcgaccac
    58561 ccgtgttata ctgctttgag atagtctcca ccgccaacca tcctgctgga cgcacttccg
    58621 atgcgtagac gcgttgttca taccagctgt gcgatcatgt tcttcttctg cgcctgcacg
    58681 gtctcgcagg cccgatcagc gacggcggcc gcccgaccaa ttggaatcga cgtcttcgcc
    58741 cagctcaccc agcacattaa acgtcaggct gacaccgaca aagaggcctt tgcgattgcc
    58801 agccaatgca tgaatttttt ttacaagcaa cagcggcata agcccgcccc gcccgccgtg
    58861 caacagattg cctggattcc cgcagagtcc tctgaactcg ctgcggcgga ttcagacgca
    58921 caggaggcgg attgccgcaa gcggtatccc gaaggactcg atgccgttcg caccgatttt
    58981 caacgcactc aggcgttgct ctccctcagc ctcacctttt acgaattcgc cttggtcggt
    59041 gatggcgacg acaattcgtt atacaacgcc cgtgaactcc acgacatcct tgtggcattg
    59101 aacctctccg ccgagccttc cctgggtgcc gcggcccatc tgcgttcgct caccgcgcac
    59161 ttcgattccc tgcacgaggc gcgtgggatg gaagcgctca tggccggcat gggcaaactc
    59221 tacgatcaag gctatcgcgt caccaccgcc gacaaagcac acttgaatcg agtgatggaa
    59281 tgatctccac ggtgatgcga tggcaggagc tggcacgcgt ctggattggc cattggctca
    59341 gtcgaccatt tcaccatctg ttcaatttga tcccgggagt ggagatcggt ttatcggcaa
    59401 cagtcgtgac ccggcttccg ctcacccatg cgccgctggc cggacgacgc gccgtccatt
    59461 tgagcgatct acatctggac cgttaccgcc cccggcaccg cgccctgatt cgagcggtgg
    59521 cggacctgaa gcctgattgg atcttcatta ccggcgatct ggtcaacgtc cgggatggac
    59581 ttccccatct gcttcgcttt ctcacggaac tgcgccgcct ggcccccgtc tacgtcaccc
    59641 tcggaaacca cgatcactat agcggcatcc gtgttgatga gttcgccgag caattcgacc
    59701 gccgcaaggt cacgttgctg ctcaaccagg tgacgttcat tcgagtagcg accggcgaac
    59761 tggcgatcgt cgggctggat gacccgtcac tccatcgcgc agaccttcgc tgcatgcctt
    59821 cggcacagcc tgggcgtttc accctggtgc tggcccacgc gcccaacatt ctggaccagc
    59881 tgcggcccga gcaccacacc gatctgacgc tctgcggcca tagccatgcc ggccaatggc
    59941 aaattcccgg catcccgaca ttctggctac cgcccggttg tcatggacga actcacggga
    60001 tgtatgaaaa aggcggccac cgtttatacg tcaatcgcgg actgggttgg tcggtcctgc
    60061 ccatgcgcgt gaattgcaca ccagaaattg tgctcctcga gtgggccgct tgaacgactg
    60121 actgtccctc tctatctccc tacccacatt aacgaatgcg ctccaacgcc tcacgcgccc
    60181 ggctccgcac ggtttgatcc caatcttcct tactgacata ggccaacttg tccttggctg
    60241 ccgtcgcgcg caggcggccg agtcccaagg cggcactcga tcgcacatag gcatgatcgt
    60301 cttccaacgc cttcagaaga tgcggcacga ccgtctcatc cccgatgacg cccagatggc
    60361 tggccgccat gccccgcact tgatgttgtt tatcgcccag agcccgtttg agtgtcgtca
    60421 gaaacaattc ctgaaagcgt ggcgcaatgg cctcaaggcc cacgcgccgg tattcattca
    60481 cttcaatcac cgcaaacgcc agctgcagtc gtttgtcggc cgcggtctgg ctctcgaaca
    60541 acttgatcaa ccgagcgcgc tgctgatttc gcgtgcggcg tgcgcgaatc tttccgacca
    60601 gcatccatac gaagaccagc accgccagca ccaaggccgc cagcgggagc gcctgatcga
    60661 tgatcagatc ctgcatctcc ggcgacaggc gcttccacac ccagacgccg gacacgacaa
    60721 gacccagcag gagaaacacg gcggtcagat tggcttgtcc tgattgtgag tgacgcggca
    60781 tggcaggcga catgataggg gggcggtcct tgcggcgtca acgcaaggcc tgtgaacgac
    60841 tcttgacagc tgccctcgcg gatgactagt ctcgcccgcg atggacctcc cggacctgaa
    60901 agacgatcct catctcaaag tgctccgccc cctggtcgag acctatctcg cattttggcg
    60961 cgcggacagc cgccatgtgc gttcgcttcg gctcaccccg tcacaattcg acgtgatcgc
    61021 gacgctcggt gacacgaagg gactcacctg cgcggaactc tccacggcta ccttggtgac
    61081 caagggcaca ctcaccggtg tactggatcg gctggaagcc aaaggactga ttcgccgaac
    61141 accagtggct gatgatcgcc gaagcacccg tatttgcctg accgccaagg gcaacaagct
    61201 gtttcagacg accttcgccg cccacattgc gttccttcgc ccctttttcc aacgcgcgct
    61261 ctccgccgcc gacgccgatc agttgcgcac cctgctcctg cgtctccatc gaagtttcca
    61321 ggagaaaccg gtcgcatgat ccgcctcacg gtgctggggt caggaaccaa tgttcacccc
    61381 acacgcgcgg ccgccggata ccttcttcaa accgatcaga cattcctgtt ggatttcgga
    61441 ccgcgcacac tctccaattt gataaagagc ggggtcgatc gccacagcat cacccatatt
    61501 ctgttttccc atttccatgc cgaccacttc gccgatttta ttcccttctt ctttgatgct
    61561 gtgatcttct gcaaatacca aggcgggacc agaccgcccc tgacgctcat cggtccacac
    61621 ggcaccgcca ccttgatgcg gtccatgatg acgacgttcc cgagtttcga tcgcccgccc
    61681 ttccgagtca ctatccgcga agtggccgat cgcagcatcc ggatcggcga gacgcgcatc
    61741 acccccgcta ccgtcactca cgcccccaaa ctgcattgcg taggataccg tgtcgagtat
    61801 cagggccatg ccgtggccta ttcgggggat tctcaatatt gcgagagcct ggtgcgactc
    61861 tgccatgagg ctgatttcgc cgtgctcgat tgctcgtttc ctgaaaaccg gcccggcgcc
    61921 gggcatttac acgcaggcct ttgcggccgc gtcgcccagg aagccggcgt caaccagctg
    61981 gtcctgtcac atttttatcc gatcgccgaa caatatgatg tccgcgcgca ggcgaaacac
    62041 tactttcctg gacgagtcag aatagcgcgg gacctgctca agctgcggag ctagtcgaga
    62101 cacagcctct gcacgatggg agaaacctga aggggagaaa cccggcttac gttgaggatc
    62161 tgaatgaggc gagaacgacg ctggtggccg tgttcagctt cctgctacaa cccttcttcg
    62221 cgctgttcac agcccaggat ttccacgaac cgtggtaagc ggtgcttttt cagcggctca
    62281 tcgagcttat tgtagatggc gaggagattt ttgatcatcc gggccagaat agctcgggtc
    62341 gggcttttct gcaggaaacg atcttcaaag ccgtagccgg cttcggtcag gaaccgcgcg
    62401 cagttctttt cggtcaacag cgccccgccg ttgaaacaat cgatgaaaat tttgtaccga
    62461 tccgaatcga atttcaccag gaagtggccg ggcatcccga tgccatgcac cggcaactgc
    62521 aaccgcctac cgatcagcag gtagacggtc gagaggctga tcggaatgcc ggtccggcgg
    62581 tccatgacgc aattcagata gctgttttcg acttcgtaat aatttttggt gttccctttg
    62641 aacccggcct cggtgaagag ataccgattt aaggctctga ccgtctcttc gccggataca
    62701 cgggacccga tctgctcccg gacatcctgc gccatacgat ccaattgccg ccggtaggcc
    62761 tgcacatcca gcgtgggata cgcataccgc gcgaggatga aggcgccggt ttccagatcg
    62821 acctgatcat ccggaaaggc gatcagatcg cggagctctt cttccaacct cgcgccgcga
    62881 atttcctcca gcacggtgac gatacgatcg gccatctccg gctgctcgat ttccgcctcc
    62941 tgaagcagcg gaacagcgca gtcgccgaaa tcgatcagtt tgccgctgat cgttttgaca
    63001 atccgttcat cctcgtcacc aaggagccgg atcagggcgc ggatttggct ttcgttcacg
    63061 aacatggaag atcctcgagg cgtcaccgtg ctcacccgat cgcccgccgg aacgccttcg
    63121 caccaccata gagacacagc gcatcgaaca acaccatcac gccgatgacc attccgacat
    63181 gaggcaacgc ctcggcccat ccctgaagaa tgagcggacg gacggcatca atggcccagg
    63241 tcatcggatt gaattgggcg agaaatccca tccagcccgg catggccgcc aagggcacga
    63301 gggcggagct caagaaaatc atgggcagcg aaaggaagcc cagcacggaa aagaagtcgc
    63361 cgtggctctt cacggaaaac gccatggcca tcgagatggc cgttaagccg actccgaaca
    63421 tcatgccgat gagcaaaatc gtcgctactc ccgccaggcc ggtcaccggc tgcacgccga
    63481 atagccaggc caccgccaag ataacgagga cctgtagcga cgtgatggtg gtgacaaaga
    63541 tgaagcggct caggataacg gaggttcgat ggatcggcgt ggacatcagg cgttcgagaa
    63601 acccgttttc cttatcgaag aggaggtcga cgccgccggc caagccgtta ttgagcaccg
    63661 tcatgaccac cactccggca gtcagaaaac taatgtaact cgacgattga gtcacctgca
    63721 gatccgccgc gcgttgaaac aggttgccga agaagatcag ccagaacaac atcggctgca
    63781 cgagcgtaaa cagcatgctg aacttttccc ggctcagccg ccgcacccag cgcatcgtca
    63841 acgcccgaat ctcctgccaa tattctttca tatctcgatc tgcatgctcc ccggcgacag
    63901 ttaggcgtct tcggccttcg gatggtcatc cttgatagat cgccctgtat gggcaataaa
    63961 cacgtcatcc aaccgaggcc gatgataatc gatgaactcc agctggcacg tcaggcgatt
    64021 cgccgcttca agaatagcgg gcaacgcttt ctcgggcgaa tccacccgaa tgtcgagccc
    64081 gtttgcggtc accgtgacgg cacgaatggc cggaagatcc ctgatggcag ccgcgagctt
    64141 ctcgacgcga tcatgttcac gcaccgtcag cgacacgagg tctccgccca acccgacttt
    64201 cagttcgttg ggagcgccca gcgctttaat tcgacctccg tcgatgatgg caatccggtc
    64261 gcacagctga tcggcctcat ccaaatagtt ggtggtcatg accaccgtaa tcccgcgctc
    64321 ccgcatggcg cgcacatggt cccagatgcg caaacggctt tgcacgtcca gcccgagtgt
    64381 cggctcgtcg agaaacagaa ttttgggatc gggcaataac ccgcaggcaa tgtccagctt
    64441 gcgcttcatc ccaccggaat aggtcttcgc cggacggtcc gcctgctgtt ccagttccac
    64501 caattttaac agctggggga tgcgtcctgc ggcgtcttcc tgagagagat ggtagaggtc
    64561 ggcgaggagt tcgaggtgtt cccggccggt caagaaccgg tcgatggccc gttcctgcgg
    64621 cacatagccg attgtctgcc ggacacggtc cgcatccttc accgaatcga ggccgaaaat
    64681 tttggccgat ccggacgtgg gattgagcag ggtgatcaga attcgcagcg tggtgctctt
    64741 gcccgcgccg ttcggaccga gcagaccgaa gatctctccg gtgtaaactt gaaacgagag
    64801 gtcctcgaca gcccgaacct tgtcgtaggt cttcccgagg tgggatacgt caatagccac
    64861 cggccgcgac atcagcccca tcctccggca ccgcgccgct ccgccagctt gaattgaatc
    64921 aaatcgctca gacggcgggc ctgttgcggc acatgctctg cttccagcag gaactgtttt
    64981 tccaacggtg tacagtcgag ataggtagag agcgaattca cgaacacctc gtcgctcacg
    65041 tcgggtcgga tcaagctgtg cagcggggag gcctcctcat cggctttcag atattcatca
    65101 agcaccccca tcaggtaccg tcgcagagct tggtccaggg ataacgaccc gtcgcgcggc
    65161 ttcaacgtga cgcgggcttc acgatagctt ttctcgaaga actcttcatg aatttcgtag
    65221 cgctccaggc cttgcagcag gatgttggac cggccatcgg ggagcatttg aacactcgcc
    65281 aatcgcccga cacagccgat ggagaaaatg ggaggattcc cttcgtactg ttcctcccaa
    65341 ccttccttta ataaggccat gccgatacat tgccctgccg ccgccgcatc cgctaccatc
    65401 tggcggtatc gcggctcgaa tacatggagc gggagatagg tcttcggaaa gaaaacgacg
    65461 ttaggcagag ggaacaaggg aatgcgttcc gggacaggaa acggctggac ctttcccgac
    65521 aactcccggt tcgacggctc acgttcaggc tcaggaaaca tggctcacga tagctgatgc
    65581 tttgcaaaat tgtcaacgct gccaccgggc cgcatctcgc tctcaaacat cacaaaacat
    65641 gcatggatac tggcgtttta tcgactgtcc atcaaaaaag acagtgggcc caggacagac
    65701 ctgaagcact gacctgcacg actggtcgct gatgtatctc atgacaccat tacgtctcgg
    65761 ttgcacgatt cgccttctac tcctggcagt tctccccgtc actgcacagg ccgtggcgac
    65821 gaatgagacg gttcacgcct tcgacatggc gacaccgggg tatcagtatc gatttccaca
    65881 cgaccacggc gcgcacgaac gatttcggac tgaatggtgg tattacactg gccacgtcgt
    65941 ggcggctgat ggccatcgat tcgggtttga actcaccttc tttcgccgag gcatgcctcc
    66001 agaccaggtg cagacgcttc cgtccagatg gtccattcag cagctctacc tggcccatct
    66061 cgctctgacc gacctggatg ccggccgatt ttattatgcc gacaaagtca gtcgcgaagg
    66121 cctcggcaag gccggcgcgg acacagaccg gttacacgtg tgggtggacc gctggtccct
    66181 gctcaccaat gatccagcag catcgcgcca ccagcttcag gcggcgaccg acagtgtggc
    66241 gatcaatctc acggtcatcc cgaaaaaacc gccggtcata catgggcacg atggcctcag
    66301 ccgaaaaggc gccgatccgg gacaggcctc gcactattat tcgctcactc acctcgcaac
    66361 cgaagggcag attcgagtcg gcaccgaaac ctttgccgtc acgggcctca gctggatgga
    66421 tcatgaattc ggctccgccg atctgggact gaatgtggtg ggatgggatt ggttcagcct
    66481 tcagttgagc gattccaccg aactgatgtg gtattccttg cgacgcgccg acggatcgag
    66541 cgatccggtc tcgagtggca cgctggtcct ggccgacgga cgcgcgcacg cactcgacgc
    66601 gcaggacctc aacatcgaac cactggccca ctggaccagt ccgcgatcca acggacggta
    66661 cccgcagcga tggcgactca cctcggctac gatgggattg gatgtgactg tggagtcgct
    66721 cctcgcggac caggaattgg atacggctcg cagcacaggc gtgacctatt gggaaggggc
    66781 ggtgtcggtc tccggtcagg tgcgaggcgc accggtcaca ggacgcggct atgtcgagat
    66841 gaccggctat gctgaacgtt tcacgccaaa gctctaacgc ttcaggcctt cgggacgatg
    66901 tctcaccttg actcagtcac gacgctgtgg ttaggtctgc gaccactgtg atgtcccaac
    66961 gaattcgaat agcgaccctg cttcggcggt cgatttgcct cctcagcttt ctgcttctgg
    67021 cctgcggcag tcgtgaatcg gccgtggtgt cgatcgcgct ccatccgtca aaccccaata
    67081 ttgtctatgt cgccacgaac gatgccgtgc acaagacccg ggacggcgga gcgacctggg
    67141 aacagtttcc agcgttcacc gcccgccgcg tcacgacgct ggccatagat cccaagcttc
    67201 ccgccaccgt gtacgccggg accatgggcg acgccattta taagagtccg gacggcggcc
    67261 agcattggct tccccacaac gtcgggctca aagagcatgt gtcgttcatc aatgaaatca
    67321 tcttccatcc cgacaacacg gaactcattt acctcgccac cacggtcggc gccttcatct
    67381 ccaaaaacgg cgggcgcgaa tgggaagaac ggatggccgg gatgaaggaa gtgcacatcg
    67441 tgacgtgcat taccatggac catcaacacc cccgggtctt gtacgcggga acgacgggcg
    67501 gcacctatcg cagtgaagac ggtggtacaa gctggcaaaa aaagaatacc gggctcattc
    67561 ccgaggatgt gctgaacgca gccatggcgt tgggcgtgaa tatgctggcg gttgatccgc
    67621 ggaactccga agtggtctac gccgcgacca ccaaggggct gtttcgatca gcgaatcgcg
    67681 gagagtcttg ggaacagatc ggccaaggat tgtcgaacca attcatcagt acgctggcgc
    67741 tgcatcccat ggatgcaaat attttctaca tcggtggccc ggacggtgtg cgaaaaacca
    67801 ccgatggcgg aaaaacctgg caatcacaga atgagggact caccacgacg aatatccgca
    67861 cgatcagcct cagcccgagt gatccccagc tattgtatct cggcaccaat ggcagcgggc
    67921 tctaccgctc gaccgacggg ggacaacatt gggcgccgat tcccctcacg ggaccacagc
    67981 aacccccacc cgcgtcataa cgaggctcgc tggactaccg atgccgacac tcctgttgat
    68041 ccgacatggg gaaaccgact ggaatcgatc gggacaagtc atgggaaacc agccgattcc
    68101 tctgaacgag accggcgaac aacaagccct cgcgtgcgcg gagatgctgg cgcagacacc
    68161 cattgcaggc atcgtgacca gccctgtgct acgggcggta caaaccgccc acatcgtcgg
    68221 acgtcgccat gcagcgcccg tgcatcatgc cccgggactg agagagatcg gcgtgggaaa
    68281 ctggatcaat cgctattgga aggatttggc ggatgatccc gccaagcgcg actggtatct
    68341 gcacccggac cgggcccgcc cttcaggcgg tgaaacgctc tgcgaagtgc aacagcgtgc
    68401 cgtcgcagca gtcgaacagg cgctgcaagt ggcgcaagat ggaccctacg tgtttgtgtc
    68461 ccatggcgac gtcattcggg cgttgctggc ccattatctc cggctcgact tgaatgcgct
    68521 gcgccaggcg cgcatcgacc atgcaggggt cagcggcatc gaggtgactg aagccgccac
    68581 ccacctgctg ttcctcaatc atcgcccagg cctccccagg ctggcctgaa ccacactcca
    68641 cgccgttact ggtgcgcaga tgctccctcc gcgccttttc cgtagtagcg gctgccatac
    68701 cgcttcagtt cttcggacaa ggcggtccat tcctcagccg tcaacaaggc tttcatcttg
    68761 aaccgaaggc ccaagatctt tgccgaggaa cgcatccggc tgttattcaa ttcgtcgagg
    68821 attttggtga actcctcggg cgcagctgaa tagtttgcgt tcaactcata gagcgcgcga
    68881 tgaaactggc gatgttgttc ccgagccgac ttgatctcgg cgatcatctc gcccatcacc
    68941 acgttcacct gcttgacggt ttccggattc ttgacgtgtt tttccaccag gccgctcaca
    69001 tcctgagagg ccttgcccca ataatagtcg cccttggcat gctcataact tccatggtgg
    69061 tgggaacaac cggtcagtcc ggtcaacagc acaccgacaa gaagacacag ggatcgaacg
    69121 ctcatcacaa cctccattga aaaaaatgac tgtgtcgcat gaaaacgcgt tgcgccgcag
    69181 cgccttcctc ccgtaagctt tccgaacacc tgacagggca aggagtacgg gtatgggcga
    69241 acaaaaggcc cctcaacgcg gaacagggcc ggtcgaatca ctccgggacg aattccgtca
    69301 acacctcgac gtcttttaca gccgcctcaa actggccgct ccctacgaca gcgtcgaaaa
    69361 ggccttgggc acgctcacca ccacgctcaa agcgttaccg cctgaggaac tgcaacgtct
    69421 gggcgcagac cagacccagc gatgggctca ctttcggcag gccttcgtcg attcgggcct
    69481 gatccagaaa caccggggaa ttattgcagg cctggcacga tccagcgcct caccggatct
    69541 gccgcccgaa ttcaatcatc tgctcgatct gtatcgcccc aaaacttagc tgacaggttc
    69601 acgaaggcgt gctggattca ggcgatcttt tggcaaatca ggggcgcgat gctgcccctt
    69661 cattggccaa cgcgatgtct ctcagttccg tgtacacgag catcagccgc gtgttttcga
    69721 tgcgataggc taccgtgacc gtcagcaacc caaaggcgac gacgatcaat ccaactccgg
    69781 tcacgccaat ccccagcagc acacttccca atgactcgag cccgccctgc aacacgtagg
    69841 tgatgaggaa cccgagcgtt ccgaatccca cgagactgaa ccagaggaac gtcaagatcg
    69901 aggacgacca gggtacccgc ttcgtacaca ccatgcgcag gccgtcagag tccgatgcca
    69961 attcgatgct gcccttgagc ggccaggccg tgcggaagcg catcgagaac aggcgatgcg
    70021 tggggcggat gatcattcga ttcgcgtcgg gaaacacccg cgcgaccccg tgaggcaagc
    70081 tcaaaaaccc attcgtgtcg aacgcgcgca ggagctttgg aaccgtgagg gccgcaaacc
    70141 ggtcctgcac ttgcccgatg ccatagccgt accgggtggc atcggacgag aggcgggtaa
    70201 agtacatcca gtcgccgacg atcaatccga taaacaacac gatggcaaac gcaccggcga
    70261 gcatcatagc cgaaacttcc cacagggctt tacggagaat caagtccgaa ccgatggtga
    70321 cggcaggcaa aaagcaggag gaacctgttg actacccatc tgcgcattgg ctacattaag
    70381 cccgttctta tccggcgggt gaggacgagt catccgagtt gcgttcccgc cttcatagat
    70441 ttttccacgc cacacttctt atcgccgtca cttctgcact gcagagttgt gcgggcagag
    70501 cggcgtgatt ttgcggaggg acgatggata tcgccaaagt cgagcgtgtg tacaccagtt
    70561 attccggcgt ctatgatcat atcttcggaa aaatctttca tgagtcgcgc gaagcctgcg
    70621 tgcgcaacct ccgaatccgg ccggaagaaa acatcctcga agtcggcgtg ggaacgggaa
    70681 tcgccctcga atattatccc aagaactgca acattacggg tatcgatctc tcctcaggca
    70741 tgctggccaa ggccagacaa cgccagtcgc actatcattt ggaccatgtt cggctgatgt
    70801 tgatggacgc cgggaaaatg gaattccccg acgatagctt tgacacagtg atggcggcgt
    70861 acgtcgtcac cgccgtgccc gactatcgca aagtcgtcaa tgaaatgatc cgcgtgtgca
    70921 agccgggcgg gcgcatcatc atgctgaatc acttcagcaa cggcaataag gtgatcgccg
    70981 ccgtggagaa agtcatttcc cctctctgca agcacatcgg tttccgtacc gatctctcgc
    71041 tgaacacggt gctcgaaggc accgacctcc acgtggcccg aaaagaaaaa gtgaatccga
    71101 tgaagttctg gcacttggtg gaatgtgtca accggaaggg tgccaagagc agcaatggga
    71161 acggcagcgt aaacggaaat ggcaacggtc ggcacgggca cgtcagttag agtgcttggt
    71221 ccgttgagat ttggatccgg cctatgggcc aaatcctcac tcgtcttttc tcaccactcg
    71281 cttgaaacgc ccctctcgcc agtcaggcag gtacccacat accgctgagt gaccacttca
    71341 gtcaccgccc tcaacaaccg gccgctgaag cggccagtgg cgagtcgagg ctgcagtctg
    71401 attccgaacc ctgctccgtc gatcggttca taggcccgca cggtcagcgc tgccgtgggg
    71461 ccggcattca cgtcggcggt agacaccaac tccccttccc aacacaaagt cccgtgatgg
    71521 cccgcacgcc gcggcgtcga tttccatatg caagggaccc ctacctgatc aagttgggtc
    71581 agcagccaat ccaccgtggg agggtcaccg gaatcagcct gaaagatcca gggcgcggct
    71641 ccctggtgaa tgtccccgtc gctatgcggt actgacacct cctccaagag cgcctcttca
    71701 cacaccacgt acaggttccc ctgcggatcg aaccagaagc gcaggaggcc ttcatgcaac
    71761 tccacctgaa tcattcccag agcagcacag tccccgccgt cctgctcaaa gacggaaaag
    71821 tcggagacac cgtgcagact gagtttggca atcctgagga cgccttgcag atgatatcgt
    71881 acggtgactg tcacgactct ccctgccgac acgtcccggc ctgactcttc gtcgagcatc
    71941 cagcgtttgg ccaaatgcac atccatcaca cgaccgccgc gaaacccctg cgtgtgcgtc
    72001 agcaaccaac gaacgtcgtc ggccgtttta atcgaatgtg tcatcgcaac gtgaaaacct
    72061 tcaagcaaga tgccgtctat cgacaccctc tcgaaccact gtatcacgcg gacgccggag
    72121 aaaagcgagg gaaacgacgg ttccaggaga ggaggtaacg gggaaaggga cactagaaga
    72181 gcacttgctg ctgcttggct tctgccagtt ggcgctccaa ttcctctaca cgttcctgta
    72241 gacgctgatt atcaaggcgg agaagatcga gacgatccag caattgttcg cgctgaatgt
    72301 tggtccattt cagtgtgcgc tgcaagccag ccagttcaag ctgtgcctgc tgcccgtctt
    72361 caaacgcgga gcccatgcgt acgcctcagt caatcgccat caggagtgat aggcaaatcg
    72421 tagcgcactc ttagccagtt gcggagcgat tagtgattta tcgacgaggg acgcgcggga
    72481 actgctctca gctgcgtggg tgagacgaaa ctctctcgaa gggcttattt ttcgcgagct
    72541 cgcaagggca aggtgctccc ctcgaggtcg tcgctggact cccagcgata acgaaccagc
    72601 acgccgttag cctcccaccc gggtgggcag aggttgcccg tgccataata gtcggcatcg
    72661 agcactggaa acggcacgac attcttgatc cagtcctgag catggccgtt agactcgata
    72721 taggactgca aaaaatacgc gccgccggtc aaaggcaggt cgggcagaat gaaatccaca
    72781 tacccggttc cacgtagggt caaaggcgtc ggatcaacga tatcggtcga caagacgaat
    72841 agatcctgtc ccttccgccc attgacggaa acgctgaccc ggcagttgcg aaattcttta
    72901 ccctccgcgc agcggtagtg catccggatg atcacatccc gtcctgttat ggcagaagtc
    72961 acggagtgcc gatccttgtc cagtagatcg atctcagtga gcaggatctc tcccaggccg
    73021 actcggtccg ggcgatcgcc gatcgacatg ctcgcctggc tgcgaatcgc atcggcatat
    73081 ccttcgacta ccgtctgcgt tttgccgatt cttgcgatgc gcccattttc tagcagaatc
    73141 gcccgttcgc aaagcccttc gatgataccc atattgtgac tgacgatgag gaccgtgcgc
    73201 ccgcttcggc tcacttcttc cattttcccc agacactttt gctgaaaact cgcatcgccg
    73261 accgccaaca cttcgtccac gatcaaaatt tccggctcga gatgcgcagc gacggcaaag
    73321 gccaatcgta catacatgcc gctcgagtac cgtttcaccg gtgtatcaat gaagtcttcc
    73381 acaccggaga aggcgacgat ctcatcaaac tttctccgga cttcgtcccg tcgcatgccc
    73441 aacatggccg cgttcagaaa aatattctcc cggccggtca actctgagtg aaagcccgtt
    73501 ccgacctcca agagcgagct gacgcgcccg tagatatcca cggtgccttt agtgggctgc
    73561 gtgatgcgag acaagatctt gagtaaggtg ctttttccag ccccgttgtg cccgatgatg
    73621 cccagcactt ccccctgctt cacttcgaac gaaacgtcct tcactgccca aaacgaggga
    73681 tcgggttcag accggccgga gccccatcga gtgagggact tgagccggtg catgagctga
    73741 tcacgcagcg tgttgtgctg gacagccgcc cccagtcggt aatgcttgga tagcccttct
    73801 gctcgaattg cgacggtact catctaaatc acgtccgcaa aggtgcgttc catcgaacgg
    73861 aaatagatca atccgccaat gaacacgaca aaaacaatgc ccagactggg aagaaccatc
    73921 gaaaagtcga cctgaaagcc cggaatcaat gcccaccgga atccttccac cacactcacc
    73981 accgggttga gtgcatagat ggcgcgccac gattccggca ccttactcac agggtacaga
    74041 atgggcgaca cgaacatccc caactgaatg aacatcggaa gaatatgacc gacatcccga
    74101 tatctgacgt agagcgccga aacccagagc cctgcggcta atgtgatcat cgcccccaat
    74161 ccggcgaaca gcggcaggaa cagaattctc caggtcggca tcacttcgaa ccaggccatg
    74221 agaccgagaa acgcaatgaa tgccagaaat aaatcaacca gcggcgcaat cgtcgcggag
    74281 aggggaagaa taagccgcgg gaaatacacc ttactgatga gtggcgcctc tcccaccaag
    74341 ctggtcccac cccgactcaa tgcctgagag atataaaacc atggcagcag tcccgcgtag
    74401 agaaaaacag gatagggaaa accgtcggag ggaatcttcc ccatcacgct gaacacgacc
    74461 gtgaaaatca gcatggtcgc cacaggctgg aacatcgccc aggccacgcc taacagcgtc
    74521 tgcttgtacc gcacggtcac atcacgccac accagaatat ggatgagctc gcgatactgc
    74581 caaagggcag ccaaatccaa ttccagcaaa cccttggccg gctgaatgcg cacatgcggc
    74641 agcaccgccg gatgtcgctg gtcgatgttt acaacagaca tttcgtttga gtggttccta
    74701 taggcctaga catgtccagc tggaggacga cgcgcagaga ccgaaatcct agtgcagccg
    74761 cacaattgat cctaactcgt actgaatacc atttgttatg tcaaattcat gacgctcggt
    74821 caagctcgat acattgccat tggaacaaca tttctctctt gaccctatct ctgaacaaca
    74881 gctcttccga atggatgcct gagcgatcct gctgccggta aaaacgcgga agccacaggc
    74941 tcgttgactt ctccagcctc aacgggacaa tcgatacacg gagtgacgaa ggaccgtaac
    75001 agtcgcttca gccggcaggg agcccggcta tggcgtagag aggggaggct tttgtgcggc
    75061 tcgcacttct tctgctgaga gataccgaat cgctaaccca gacatgtgga gcatccaacc
    75121 ttgcccgccg ccagcccctt gagtaaagct ccacgcgtcc atccggaacg ggttccaata
    75181 cccgctgcgg taagaattgg tattcgatac cccgcccggt acggctgtgc ccatcgttga
    75241 ttgaaacgtc gggcctctat ccgacagacg ccggacatcc gcgtctccta atacgaccgc
    75301 gtcagccccc aattctttgg ctcgctcgag aatgcggtca cgcaaggtat cttcactggc
    75361 atattcactc gtagcgacaa tgcgggcgat ttgcacgtgg ccgtggttag gctcgcgttg
    75421 taacgtcgtc acagcatccg cgcccgatcg aggttcaaac gccttggtgg tcaacggatc
    75481 cacctggaca gagacacagg cgctcgaaag ggctagggag agcacggctg tgaggtggat
    75541 cgctcgtctg atcacaacaa cgcctcgtgt gtttaggaat taccgcccgc ccgtgatgtt
    75601 catgtcgcct tggctaccat gcatcttgac gactcaggtc aatcaaatca accacaaatc
    75661 gcctgccctc gcagcttctc cggggtaatc ctgcatcacg tggggtaggc tgtccaattt
    75721 cgtactacaa tttcccttca acgagggtgc gaatctcttc catgcgccgc cgattcacac
    75781 caaggtcgct gtagccggtc ctggaagccg agcggaattg aatcatcttc gttgcgtcat
    75841 caaaaacaaa ttccacatca tcgatgaacc gcagcaagaa gctggtgaat tcatagtgta
    75901 gatacccgtc gttttcttcg acgagtcggg tgcgaggcaa tcgattgatg atggtcttca
    75961 gcgtgttttg cgcgccagcc agattttgct gataccgata tggcgcgatc tggcgactct
    76021 gatccgccgc ttgcgtcgac acgcagttgg gactcgaggg gcagggcgca agtattttca
    76081 tggcatcgtg gttaggatgg ttagaacgta caccgaactc taataagccg cgcctggtct
    76141 gtcaaccgtt cgcccattgc aaaccacgtc tcaccggcgg cccgacggca ccgcgctggc
    76201 acttgtgtcc gctcggcgag cgactagccg ggcgtgccaa cgtggcacgg cctccatgcc
    76261 gggcttttcc accaggcgga acgtcgcaga acagaggaga atcagcgcag gaacctgaca
    76321 cagcaccatg gcccaatgct cggcggggga tagcgtggcg gccgactcgg ccagcaagag
    76381 ccggtaggtt acaaacaaca ccacactatg caggagatac aagctgtacg ccatttcgcc
    76441 caggacaatc gacgccggcc attcgagaat gccgtaaaga gaattcccgc aggcaataat
    76501 gagaaaccca ccggccaaaa gcagcgtggc cggaaccgta tacgccgtcg gaaacgccat
    76561 aaacgcggtc gccagacaca agatcgcgat ggcgccccac acaccacggc tcagcatcat
    76621 tcggatggca gcaatacgca caagccctgc cgccgcaatt ccaccggcaa acgcatacaa
    76681 tattgggaac cgaacctgtg gcatcaccat cacaagaatc accacagccg ccagactgac
    76741 gatcacccac tgaatcggag ggcttgtccg aagacagaag gcagcgagag gcaaaccggc
    76801 atagaacaac cattcatatg gcagcgacca cacggccccg gccaagggca ccgtttccgc
    76861 aaatccattg acggacgaga taccgggaat tgtaaacagc agccactgtg ccgtctgttc
    76921 ggccacaact gccggcgcct cacgcatttg aaaacccgtg cggccaaacg acatgagcaa
    76981 tacacaggcg accgccacga gatacaacgg tcctaggcgt agcgcccgag acagatagag
    77041 gcgcgaccag tcgatcggtt ggtgacgtcc atcgaggagc tttgaccaga agagaaaccc
    77101 ggtgatcatg aagaagaggg tgacgctgcc ttgtcccagc tgcgtgtaca cattggaggg
    77161 gggaacgtcc caggtgcccg atcgcaaata gaagtaccag atggaggaat ggctgacgaa
    77221 caccgccaac gccagatacc ctcgaagccc atcgagcgac ggatagcgcg gcgttgacga
    77281 ggcctcctga agagtagttc gaggaagaaa catggccgtg gcgagcgcga caagcaccac
    77341 acccgctgcg ggccataaac ttgttgcatc catggactca cgacatcata ggacggcaca
    77401 tttgtctaac ctttctgaga tcggcgccaa cccgtcgcac ggcgatgctg acgttcacga
    77461 ccgctccccc atcagccgct gggctggagc gccactccga cactcactcc gttgattgcg
    77521 agagtggtcc tggggtacgc tagcccttcc gatttccgat tgacggctgc cagccgccac
    77581 ctatcgtaca ctgctgagcg tcaccgctca ggttcaacaa aggagtgctc tcgcatggcc
    77641 ggttttccga ttgaagtcgc cacccgcatt aaaacgctgc cgccctatct ttttgccgcc
    77701 atcgacaaga tgaaacaaga ggcgcttgcg cgcggagtcg atatcatcaa ccttggtatc
    77761 ggggacccag atctgccgac accggcgccc atcattgaga gcctctatga agcggccaag
    77821 aatccgaaac accatcaata cccttcctac gagggcatgc tgtcgttccg caaggccgta
    77881 gctgactggt acaagcgacg gttcaatgtc accctcgatc cggcaaacga ggtgctgacc
    77941 ctgatcggct ccaaagaagg gatcgggcac gttcatctcg ccttcatcga cccgggcgac
    78001 attgtcctag tccccagccc cggctatccg gtctatccgg tcggaaccag cttctgcggc
    78061 ggcgtctcgc acatcatgcc cctcacgaaa gccaacggct tcctgccaga tctcaatgcc
    78121 atcccgaagg atgtggcgaa gcaggccaaa ttgatgtggc tgaactcccc caacaatccg
    78181 acgtccgtca tcatgagcaa agactatttc aagcgtgtcg tcgagtttgc gcaggagaat
    78241 cagatcatcg tgtgccatga tgcggcctat tcggaaattt tctatgacgg caaacggccg
    78301 gccagcttcc tcgaagtcga tggcgcgaaa gaggtcggcg tcgaatttca ttctctttcc
    78361 aagacctaca atatgaccgg gtggcgcatt ggattcgccg tcggcaacaa agaggtcctg
    78421 gcagggctcg gcagggtcaa gagccagctg gactcgggcg tgttcgaagc cgtgcaagcg
    78481 gccggcatta cggccctcgg gctcgatgat tccgtgacag atggattacg caaaatctat
    78541 caagagcggc gcgacaccct cgtcccgggc ctgaaaaaac tcgggctgga ggtcgatgcg
    78601 cctcccgccg ccttctacat ctgggtcacg gtgccgaagg gatatacgtc ggcatccttc
    78661 accgctcatc tgctggaaaa agccggcatt gtcacgacac cggggaacgg cttcggcgcg
    78721 cctggtgaag gctatatccg catgaccgtg tgcacaacaa aggagcgtct tgcggaagcg
    78781 gtcgaacgaa ttcgcaaggt gggattctag cgtggcggct attgcggtgc ctcctgtctc
    78841 cgcaggtggc tgacgcagta ttcagcgtgc tgcgtgcagg acgctgagcc ggcttcagac
    78901 tatggcaaca gcatttatcg ggttcggctc taacctgggc aatcggatcg atttctgtga
    78961 tcgggcggtg accctgcttg gcctcctacc gcattcacgg ctggatgcgg tctcgtcgct
    79021 ctatgagacc gaaccgattg aggacggagc ggcccccggc cccgcatggt ttctgaacgg
    79081 cgccgtgcaa gtcgaaacga acatcacgcc caagagcctg ctggaaatct gtcgcgaaat
    79141 cgaacgggca ctcggacgag atcaagacaa tcgcaagggg ccgcgcacgc tcgatctgga
    79201 tctcctgctg tacgatgact gtgtgctgaa tgatcccggc ctcatcgttc cccatcctcg
    79261 tctccatcag cgtcgattcg ttctcgcgcc cctggttgag ctggatcccg atcgacgcca
    79321 tccggtgctc gggcaaactc tccgagaact tctggaaaca ctcgccgatc cttccattgt
    79381 ccgccggctc gatccccagc cgaactcacg ttacggatcg aggccggcat gcagtccacc
    79441 ccctgtgcag agtcctcaca cgtgaagatc atccgcacga cttcagccat ggccaactgg
    79501 agccgtggcc tccatcgaga aggagtgacg atcgggtttg tcccgaccat gggggccttg
    79561 catgagggac atcgcgcgtt ggttcgagcc gcccggttgg cctgcgatgc cgtggtcgtc
    79621 agcatttttg tcaatccgac ccagtttggt ccgacagaag acctggcgaa atatccacgc
    79681 caatttcggc tcgaccgtgc actgtgcgcg aaagaaggag tcgacgcgat ctttgccccg
    79741 accgccacgg ctatgtaccc ggccggtttt cagagcatag ttgcggttcc gagcctggca
    79801 cggcgctggg aaggcgaggc gcgcccgcac cattttcagg gcgtggccac ggtggtgacg
    79861 aaactcctgt cgctcgtcca acccgacatc agctggttcg gacagaaaga ctttcagcaa
    79921 gccgcactgg tccggcaact ggcaaaggac ctcaatcttt caggcacatt gagggttcat
    79981 ccgacgatcc gtgaacatga cgggttggcg ctcagttcac ggaacgtgta cctctctgca
    80041 agccaacgtg acgccgcacc tgtgctctat cgggcactgc aggccggagc tgctgctatt
    80101 cgtagcggcg aacggcgagg ggcactcata caacgcctca tgactcaaat gatcaagaca
    80161 gagcgatcag tcacaccgga atatctcgcc gtctgtgatc cttctactct ggaaccttta
    80221 ccgacaatcc agcgccacgc cattcttctc ggcgcgattc gcctcggaac cgtcagactc
    80281 ctggacaata tgccggtggc gatcagacgc aagccctgaa caggaaggcg atggaatctg
    80341 cccggcctcg catgaggaca ggcctatcca tccataaaaa gcgatccggc tctgtctgaa
    80401 ttatacggag atgcggggag gtgcttgttg gtacgcgagg agctcgagaa ccaattgccc
    80461 catgcgctgt ttatcttcag gttggaattc taaaaatttc atgccgatcg actgaggctg
    80521 aatcgagcag atcatcgccg cctcgacttt gatatccggt tgcccggatg gcccatgcag
    80581 cacgaacgtc acgaaggtcc cgcgtggaag cggtgtggtc gcctgcaacg tacacccacc
    80641 catggaaata tcggtgacca cccctccggc cgccgtgtga tcgagcctca gcgtccccgc
    80701 aaagttgacg ggcaaccgac gatactcacg gcgatcgaat gcttgcgtgg tcaaccggtt
    80761 acccggccgg cgagcctgaa agcgagtcgt gcagagctgg caccgaacct gaaaaatgga
    80821 cagccggttc aacgtcttct ctataagact tgtcccggac gtcactctga cgcacggcgt
    80881 accgcaagcc ggacaataca actctttcat actacgcttc tgactcctga ctccttgtct
    80941 ccagatgcga ggcggagccc acgcttcccg acaactgttt tgcaagcagt ggtttgacat
    81001 ccgcgggaga gtaggtcgga ggtttcaccc actttccatc ctcccgcttg tagccgccca
    81061 ctttgctcaa attcgatcga tgcacctcac ggaacaccgg atccatatct acgccgtagg
    81121 acaccgccgt gccgtacacc acatacaaca gatcagccag ttctttcgcc accgccggaa
    81181 gatcctgcgc agtcatggcc tcctgcagtt cggcaaactc ctcttgaatc agccgcaccc
    81241 gcagttgccg ggtggcgtca ggaggaatcg acggccgctc gccgatgggg atatcgaact
    81301 tgcggtgaaa ctcggccacc atgtcctggg gctgcatcat tcttacgttc tcatatcctc
    81361 ggccgcaaag ggaaatcctg tcctcggctc gataccggtg gattccagca tcgcaaggtc
    81421 tttctcagat gatatcccga gatctttaaa ttttctagcg gcaggcaaca cccgggtttc
    81481 caaggaggcc accgccttgt tataggctcc gacgcttttc cctaaggcct gaccgatatc
    81541 attgagatgg tcggtgagca cggccatccg ctcgtagaga tccttgccca gccggcctgc
    81601 ctgttcggca tgttcggtta actgttcttg cctccatccg taggcgaccg cgcgcaacag
    81661 cgccatcaac gtagtaggcg tggccagaac aatcccttgg gcaaacccat cctcgatgag
    81721 agaaggatcc tgctccagcg cagcgccgag gaactgctca ccgggcagaa acagtacgac
    81781 gaattccggt gtctgtccga actggttcca ataggctttc aggctcagcg catccatcct
    81841 ggttcgcacc tggttcgcat ggcgacgtaa atgcgcctgc cgctgctggt catcctgggc
    81901 ttcgtacgca tcgagatagg cggccaacac cgtcttggca tccaccacga tctgtcggcc
    81961 tgcaggcaga tacaccacca tgtcgggacg gagcagtccg tccattgagt caaccgagtc
    82021 ctgttccaga aaatcgcaat gggccaccat ccccgccagc tcagccacgc gacggagggt
    82081 catttccccc caccgcccgc gcaccgccgg agcccgtaag gctttgacga gattgctggt
    82141 ttcctgctga agccgctgat gggattcggc catgaacttc agctgctggt ccagtccacc
    82201 gtattcccgt tggcgaatct gttcggcctg ttgtaattgt tcctgataac ggtggagcga
    82261 ttcttccagc ggcttcacca gctcaccgat cgcttggtgg cgctgagata actccccttt
    82321 ggcttccgcg tgcaaggttt caaatgaggc gcgagcgagg ttgaggaacg cggcattgtt
    82381 ttgtttcagg gcttgcccgg acaaggcctc gaaggattcc tgcagctcct gccgcgcctg
    82441 gcttaacatc gccttttggt cttccatgct ccgactgatg acttccatcc gcgtttcggc
    82501 tttcgtccgg ccttcttgag attccgccag cgcctgccgc aactggtcaa cttcggactg
    82561 ttgagtgtcg agccgctgtt gcaatgccac tgccaaggca tcagcccttt gtgcacgctc
    82621 cccgctttcg agcaactgtg cctggattct ggattgcgtg cgagctgtca cccaccatcc
    82681 agtgaccagg acaccaatcc cgagtccggc cacgcctcct gcgataaagg ttgtcgaggt
    82741 gagatcgatc atgatgcatc ctgataaaga cagagcatcg ccgccatgcc tcgcacctgc
    82801 ccgttgtagg gaaatcgcgt agagggtacg agaaaccaga tcaaacgtca agggaccaag
    82861 cggctgatgg tgcctgtcga actcacaatg tgaaccggct cgtcctcacg caagagggtg
    82921 gtagcatagg gcacattgac caggaccgga aggccgtact cccgcgcgat gatggctcca
    82981 tgcgacagcg tgccgcccat ttcagcgatg aggccggccg cgataccaaa aagaggcgcc
    83041 atccccggat cgatgaccgg aacgacgaga atgtcgcccg gccgtactcg ctgccaatcc
    83101 tgtgtggaac ggacgatgcg gaccggacca ctcgtggttc cggcactgac ggcaatgccc
    83161 cgcagcagtc ccccatcgac ttggccggtc atggacggtc cctgctcgag aaccgcttcc
    83221 caatctcgaa cggtgtcagg cacagacgca ttttggtcac gcgttctctg ctctcggcgt
    83281 gtgcgtacga gccgttgcca atcccctgat gccccctcat tcagtgccac ccgctcatcc
    83341 atggtgagat aaaacatgtc gtcaggctga gtcagaattc cctgctccac cattcgctcg
    83401 ccgagttgaa ggaggagatg gcgcacggcc gtggagtagt agagtaaatg atggcgattc
    83461 gcctcacgca gcgcgcaaaa acggctgagc cgccgatacc accagcgaaa aaccacccct
    83521 cggtgacgcc gccagccgaa ccgccggtaa atctccgcaa gcgccgcttc gcgccgctgt
    83581 gcctgctgag tcatgacatc gcccggcgga acggccttcc cctcacgcaa ctgggtccgc
    83641 aacaacatca agaccgaatc gggctgatcc gcgatgcgcg gcgacatgat gtccgattct
    83701 cccaccgcgc ggtgtccgta atccgccaga tactcatcaa accgtcgcag aaagccggtg
    83761 ccggcgaggg cctcgcgaaa ccctgaggcc gcccagcctt ctctcagaaa ccaccgctga
    83821 accacgctct cacgacttgc gacttcgact aattccgcca gacgcaaaat gtgttgcgca
    83881 ctgatcacgc ttccctggcc ttgcaaagag gcgttcagca attctcgcca gtcttctccc
    83941 agccacccgg gcaagaaggt acccattgcc tgcagactct gtgcgacccc tccagcgatt
    84001 ccgaacgtga cctcgtgcgt atcaagccat tgcccaagac gatccagcgt tgctgcaagc
    84061 tccttcgccg agaggttccg gatacggtcg ggtcgatagg tctgcgccat gtctttcatc
    84121 gcgacaaagt ttgccgggcc ctggcgcaca accctccgcc attcccgcat catcagcaca
    84181 ccggcgcgta ccagcgcgag cccgctcaaa ggacgcaccg atggcgtaaa gcccaacggt
    84241 tccccaccca tctgctcggt taagaacgac gggttcccat gcaattgtgt gacgagggtg
    84301 taaaacaagg tgacattgag atagggccgt ccatgcatca cgcgaacgga tgagaggccc
    84361 tcaggaaccg tgcacccgag gcgccgatag ggcccaacga tataggcatc catgaaccgt
    84421 tcaaggaacg agaggcccag cgggctcggc aattccggca tggtttcttt caaattcgcc
    84481 cgtgtccact cgcattcatc attcgtcagt gccggggagg gttgcaccgc ggtgatcggt
    84541 cgcgcctgta ccacccacac cttatcagcg tcccacaccc attcgaggtc tatcgggtgt
    84601 ccaaacgcgg cttcgatgtg cttcgacaat gtggccaact cgaaaagctg cgcatcagac
    84661 aatgaggact gcttctgccc ggcttcagaa atcgactcgg tgtgcagtcc agcaggggtg
    84721 gacagcaatt tctgcacttt cctggccagc agacgccgcc gaatccgaat tggccgcccc
    84781 tcgtcttccg ccacttcaac gacatactgg tccggagtca cctcgccgct gaccagagat
    84841 gcggcaagac cgggcacggc gttgacgacg acctgagaag tgcgccccgt gaccgggtgg
    84901 atcgagtagg ccacacctgc ggtagtggct tgcagcagcg gttggattac cactgccatg
    84961 gatgggaaag attttgaact gctcgtcctg agggcatatt gcaccgcggc gtcgctccac
    85021 aaggactgcc aacaatcgca gatccctcgc aaaatctcgg aagacgacag gccgagggac
    85081 gtgctataga ggccggccgc gctggcttgc tcgacatctt cgttcgttgc tgaggatcgc
    85141 acagcccatc gtgttgtcgg atcgtgcgtg agctcgacga gccgtcgttc caatgcgatc
    85201 tgaaatcctg tgggccacgc ttgtttcagc aggcaggcgt gcactcgtgc cagctcctgg
    85261 ctccgttctt cctgtgaccc ctgtagaact cttcgccaga cttcttcggc attaacgccg
    85321 cctgcggcca ggacatgacg gtagaccgtt gtcgggacac acaatcctcg cggtacggcg
    85381 aaaccagcgg cgagcaaacg gctcaagccg gcagccttgc ccccgaccag actcggatcg
    85441 cggctctctt ccagagagag aatcagtgat ggaatcatgg agagggatag taactagagt
    85501 gcgaggagga ggtaaagatc gttgacgttg gtcccggtgg gaccggtgac gatatgaccg
    85561 tgcagtttct cgaagaatgg gtaggcatcg ttatcttgca acgcctgaga caggtccagc
    85621 ccctttcggc gggcccgcac gaccgtctgg ccatccacca cagcaccagc cacagacgtc
    85681 ggcccatcag tcccgtcagt cgcaaaaccc gccacccaca cgttgggcaa tcccgcaatc
    85741 tcaggtgcgg ctgccaacgc aaactcttgg gctcgtccgc ccgttccctc ccctcgaatg
    85801 gtgacggtcg gttctcctcc tgcaatgatg cagcaggggc gcgggatggg acgtccatgc
    85861 cgcgccatct cacgagccat ggcgccgaac attttggcga gttccctcgc ttcaccggta
    85921 agtgtcgtgg acaggaccaa cgtgcgtagc ccttgttgct gtgcagccgt ggcgacggca
    85981 tcgactgcgg cttgattgtc tccgatgagt atgttgtcga cgcggcgaaa taccgaggcg
    86041 cggggtttag gtgtctcggg tgcacggtgt ctcatcccca tgctgagccg attccgaaca
    86101 gatgccggaa tagttttgac gaccccatac cgctcaacaa tctcccaggc ctcccgaaag
    86161 gtcgttggat caggcgcggt gggccctgag ccaatcgtac cgaggtcgtt cccgatgacg
    86221 tcggagagaa tcacgctggc cacgcgcgcc gcagtcgccg cagcgagctg cccgcctttg
    86281 acgctggaca ggtgcttgcg tacggcgttg atctcatgaa tggtcgcccc ggaccgcagc
    86341 aataatttgg tcgtctgctg tttatcttgg agcgtaattc cagacacggg ggcagggaga
    86401 aggctcgacg caccaccgga cagaagcacg atgagcagat catccctcgt gagcgtcttt
    86461 accaccgcca tgacctgacg gccggcctca agaccggcga catcgggaat gggatgcccg
    86521 gcctccacga tacgaatggt gttggtcggc gccccatgac catacttcac cacaaccaaa
    86581 ccggcgtcga tccgcggccc cagctggtgc tcgagcgcct gcgccatgcg ggccgacgcc
    86641 ttcccggcgc cgaccacgac gatacgtttc acttgattga gagaatactg ctgcgagccg
    86701 atggtgagat gcctgcgtcc gatgctgacc tgacgccgca ccgcctcata gggatcaacc
    86761 gcgtgcaatc ccgcctgcaa cagcctggcg agaagggctc tggtgcgagg ctgcgggacg
    86821 ccgatttcga tcatgcgaac tatggaagtt tatcttgctt gaaacagcgg ttcggacagg
    86881 tttgtcgggg caccttaacc tgataactcc cctttggcaa gtagtccttc gtgaactccg
    86941 gattgagcat cttcagttca aggaaatagg tgccatactc ttcggcgata gaggtgagcc
    87001 ggcgctgcgc ctccttaatg gtcacggtca ccgtctctgt ttcaagcggc ggatagagat
    87061 ccttcttggt caagccaaga tacttctccg gctgggaata gatttccttc gccgcaataa
    87121 tgcgcgcgac ataccgcatg gtttcccgcg ggccatgcat gcgccagaaa tccgtcacat
    87181 tctgttcctt gagcagtttt cgcacccggt cttcgcccgc gttataggac gccatggcta
    87241 ggaaccagtc gccctgcagt tcccgaagat agcggagata cttgatggcc gcttcagtgg
    87301 acatctcgag attgcgacgt tcgtccagcc agcgttcatt gtgcagcttg tagcgcttac
    87361 ccgtggagtt aatgaattgc catggacccg acgctttggc tcgagaatag gccgcggcaa
    87421 tgcacttact ctcgaccaac aacatgtatt tcaggtcatc cggcaagccg gcatcagcga
    87481 gttgcttttc agcgggggca aagcaccggc ccgttcgctt cgccaggata atgctttcgc
    87541 cttgatcctc gagaaactga tagaactcgt attcgatgcg ctcacgcacc tgccaattat
    87601 ccagtggaat cgactgcccg gcgaaggtca acttgtcggg cagcttgaat gaacttaaga
    87661 aaaagcgctc gccctcgcgt ttgatttcag gaaggatgac gagccggtct tcgagctcag
    87721 gggcaccctc tggttcggct gacagggggc ctgttccgcg ttcgggtatg ggaacgcggg
    87781 agtcatcgct cgcgctcggc gaagaaggcg ctggggcttt cgaatcgaga gagacttctg
    87841 caaacaacgg tgccaagccg agcaccatcg tgacaccaac tacgaaggcc cgaaggcccc
    87901 aatcattgtt ccgcatgccc gacgtatcct ttcatgacac tgaaagcccc atgctatcaa
    87961 caagcccctg acgggacaag aaactcgtcg gtttgataca cttcaccatc atgtcgacac
    88021 tctcgatgct caatgctgac atcattgcct gcactcaatg ccctcgactg gtcagttacc
    88081 gcgaatccgt tgcggcgacg aagcgtcggc aatatcggga gtggctgtat tggggaaagc
    88141 cgattccggg atttggggat ccacgtgccc gactgtacgt tttggggttg gcaccggcag
    88201 cacatggagg aaatcgaacg ggacgggtat tcacaggcga tcgcagcgga gattggctgt
    88261 atgaggccct tcatcgattc ggctttgcca accaggccac gtccaccgat gtcgatgacg
    88321 gcctcgctct tacggactgc tatatcggcg cgactgtgcg atgcgcgccg cctgcgaaca
    88381 agcccacgcc ggatgagttc acagcttgtc gcccgtttgt gttaggtgaa ctgcgcctgc
    88441 tggagcacgt gcaggtggtt gtcgtgttgg gcaagattgc gtttgatcac tattttaaag
    88501 cgtgtcgcga gatggggcga gaactgccct cacccctgcc taaattcggt catggcgttg
    88561 catatgagtt agcttggggg gtatccctga tcggctcgta tcatccgagc cagcaaaata
    88621 catttacggg caaattgacc aggcccatgt ttcaccgcat tttttctgat gcggcgagcc
    88681 gccttgaggg gaaccggcgt gggtccccct cgggttagtt gcaactactt cttccccatc
    88741 gcgtcccagt ccgccaggaa cttctttaga ccgatatcgg tcagcgggtg tttgaccaac
    88801 tgctgaaaca ccgaataggg catcgtgcaa atatgcccac ccgccaacgc cgcttcgacg
    88861 acatgctgcg gatgcctgac gctcgcgacc aggacctggg tcttgaaatc ataattcttg
    88921 taaatcgtga caatctgcct gatcagcgcc attccatctg agctgacatc atcaagccgg
    88981 ccgataaagg gcgatacgca ccaggcgccg gccttcgctg ccagcagcgc ctgcgtggga
    89041 gaaaagcaca gggtcacatt gacacgaatc ccttcggcgg aaagcttctt ggtagctcga
    89101 aggccttcag gaataagcgg aacttttacg acgatattct tgtgaacctt ggctaaatcc
    89161 cgaccttctt taatcatggc ctcggattcg acaccgacga cctcggcact aatcggacca
    89221 tcgaccatat tgcagatttc cagcaacatt tccttgaaac tacgcccttc cttggctacc
    89281 aaagatggat tcgtggtcac gccatcaata aggccaaggt tggcgccttc ttgaatttct
    89341 ttgacgttcg ccgtatcgag atagagtttc atgaaagagt cctttctttt cgcttcaaat
    89401 tttcacgttc ttgtgtcacg ttttattcta gaagcaagtc aaaggcaagg caacgggtca
    89461 actttcctat gatagactcg tttgacacat caacatctcg cagaatgtcc gcttcagcgc
    89521 ggacctaatc aggagggcta gccgtatgcg cgcatccgtt tggcttctag ccgtcggcct
    89581 tctcgtgggt gcttgcagcc ataatcctta cttggacaat tcattgaccc gttatcaagg
    89641 gaaagaccgc gcgtggatcg aaaaggaatt ggggcctccc gacgcaaaaa ctactcgctt
    89701 cttcggagga gagaagtgga cctacaatcg aattgccggg ggaaaggcag gaccgccgct
    89761 gtttaatttc aaggcgaacg aatgccagat gatcttgttc tttgataaag atgataccgt
    89821 ctcggactcg acctattcag gctgctagcc agaaagctgc ttctcaaatg cggccgcaca
    89881 tccgcggctg caaaaaaaat aggtttgccc accaatgttt tctttcacgg cattctcgcg
    89941 agcgacaaag acgcgacaaa cgggatcttg taccatttgg ttgccggaga gtctgccatc
    90001 ttttggtttt tccagtgcac catcctgccc aatctttctg atcgccctcc ggatcaggta
    90061 gtaaaggacg atcagcagta cggcaatcag aaagaatcta tacattgtgg tacttcccta
    90121 acctacccac gaaatgtcca ggggtgatcc cttcattcat tcccgccacc tggacatatt
    90181 acgagcatgg aacaatccct taagggcatt actaggaccg aatggcccag atacttccat
    90241 ggctatgagg gccttttccc ctcgagcaga cagtacttca gatggatggt ttatcctaca
    90301 gcgtaatgtt ataagccatc catgcataaa tgtgacaaat gccgcggaac aatgttgccg
    90361 gaacgggcgg ttgatctgaa tgctggttta gcgatcacgg tgctggcttg cctgaactgt
    90421 ggacgccgaa aagcagccga tgcggaaccg agaccgatca cgtcgcgaca ttgagccgat
    90481 gcagtaacat tcgatcttag agtgctcact tgcgatgagt agggggtagc gacgtaccct
    90541 ctacagagta ccgtcctcct ctggacttcc gtaccacccc attgcacgat aagcctcctc
    90601 cgtttcatac ggccaacata cagagccaac tgctagttgc gccgtgtctt gaacgaacag
    90661 cactcctccc ttattcaatt cagattggtt caaatatagg cgcaaaggga cgggatccgc
    90721 cggcgcttcc tcatgcggaa atagccgtac accttgcctg agatcgaatt cgttggaaac
    90781 aacttacttg agactcaaca catccagcat gtcataaaga ccgggaggtt gcttcaccag
    90841 ccatctcgcg gctcgtaatg caccccgtgc gaacgtatct cgactgctgg cgcgatgcgt
    90901 aagctcgata cgttcgccca tggttccaaa catcaccgtg tggtctccga cgatgtctcc
    90961 ggcacgaatg gtctggatgc caatctctcc ctttttacgc tcaccgatca atcccttgcg
    91021 ggcatacacc ccaacctgtc ccaggtccct attgaccgct cgtgccagga cttccgccat
    91081 cttgagagcc gttccgctgg gggcgtcctt tttgagccgg tggtgcgctt caatgacttc
    91141 gatgtcatag tcctcgccaa gtgtcttcgc catctccgca atcactttgt agatgacgtt
    91201 cacgcccacg ctcatattag gcgagaacac acatggaatt tgtttactca cacttcgaag
    91261 ttcgtctaat tcagatgggg aaaatcccgt tgtcccaacc acaattccac ggcgatgctg
    91321 agccacgatc cttaaatgcc cgagcgtcgc cgcaggggtc gtaaagtcaa cgacgacttc
    91381 ccctcgttcc atcagacttg aaagatcctc gacgatcggc acgcctgtcc gcccgcaacc
    91441 ggccacttcc ccggaatcct cacccagagc atgatggccc ttgctctcga cagcccccgc
    91501 caatgtcaga aatgccgaat ctttgaccag ggacacgaga cgagaaccca tccgtccggc
    91561 agccccagtg ataacaacct tgatcatggc accatccttc agaacgaacg ggctaactac
    91621 accaggccag cggccttcag tacagtcagc agtttcgcct tattgtcatt tcccatgggg
    91681 cagagcggca accgtatttc aggcgcaatc ttgcccatca gatgtaatgc ttctttgacg
    91741 ggaatggggt tggtctcata aaacaaggcc gtaaagagag gatacagctc gtaatgcatc
    91801 gcgcgcgcgg cctcgagtcg cccgtcacga aatgcattga ccaattcagc catcttcgtc
    91861 ggaacgagat tggccgtgac cgtaatgaca cccttcccgc caactgccat catcggcagg
    91921 gtcaacgcat cgtcccccgc caagacggtc aaccgctccc cgcagagctg aatgatttct
    91981 gatgcctgct gaaccgcccc gcttccttcc ttaatcgcaa ccaccgtcgg acagacggtc
    92041 agtcgcgcga tggtggaagg catcatgttc acaccggtcc ggccagggat attgtagaca
    92101 acgagcggga gctcgaccgc ttcagccacc gctttgtaat gcagaaacag gccttcttgt
    92161 gtcggcttat tgtaatacgg cgtaatcagc agggcgccat ccacgccggc cgctttggca
    92221 tgtttcgtca atgcaatcgc ttcttcggta ctattggatc ctgttcccgc caccaccgga
    92281 acacgacgtc tcacgacttc cacggtgaag gccaccacac gatcgtgctc agcatgcgtt
    92341 agtgtggccg attcgccggt cgtcccgcag ggaacaatcc cgtgggtgcc gctgttgatt
    92401 tgccattcga tgaggtcacc gagcgcacgc tcatcgagct tgccgttttt gaacggcgtc
    92461 acaatggcca ctaaagaccc tgtaaacatg ggacgctcca tcaaggaaga gaataaaagc
    92521 ccgacttacg aaaggaactc cggcacgtgc tcgcctcgga ccaggtcttc gtaagtctcg
    92581 cgcgaccgaa tgacgtgata ctgcccttcg tgcaccaaaa cctccgggac gcgagggcgc
    92641 gaattataat tcgaggacat gacaaatccg taggcaccgg cgctcatcac ggccatcaac
    92701 tcaccagcgc ccattgccgg catgacccta tcctttgcca aaaagtctcc ggattcgcat
    92761 acggggccca cgacatcaac ggttttcttc tccccttgcg taaccttctc gtacacggga
    92821 cgaatatcgt gataggcatc atagagactg ggacgaatca aatcgttcat cgctgcatcc
    92881 acgatcagga agcgtttggc ttcgccgtcc ttggcataca acactttagt aagcatcact
    92941 ccggcattcc cgacgatcac gcggccgggt tccatgatca gcacacactt caaatcgcgc
    93001 acgagtggag aaatggcctc ggccaggtct ttcggttccg gcggcgtctc atcggaatag
    93061 gtaatgccca agccaccacc gatgttcaca taccgaaggg gaatcccttg ctctgccaac
    93121 gtctgcacca tcgttaacac tttcttcaac gactccacaa acggggtcac ttgcgtcaat
    93181 tgcgatccga tatgcgcgtg cagccctacc actttgatat ggctgaatgc cgccgcattc
    93241 ttgaattctt caatcgcccg atcagccgca ataccgaatt tgcttttttt caagccagtg
    93301 gaaatgtacg gatgcgtctt cgggtcgata tcgggattga tccgcaacgc cacccgggcc
    93361 ttcacgtcca tggaagccgc cacctcgtta atggcctgca actccgcaga cgattcgaca
    93421 ttaaacatga ggatgtcggc cttcaacgcg tcacgaattt cttcctgctt tttccccacc
    93481 ccggcaaaga cgatctttga tgccggcacg cccgccttca gggcacggaa gagttccccg
    93541 cctgaaacga tatccactcc gctcccctcc ttcgccatga gccgaaggac cgcgaggttc
    93601 gaattcgcct tcatcgcaaa ggcaacaatg tgcggaatgt ttttaaaggc gccatcgtac
    93661 acgcgaaaat ggcggactaa cgtgtggtga ctatacacat aacaaggcgt gcccacttct
    93721 ttcgcaatac gcgaaagcgg cacctcttca cagtacaatt ctccattccg atattgaaag
    93781 tcatgcatgg taataatcct cgatcaacaa ttctaaactg gcccgtaaca agtgtcggac
    93841 cgccgcggcg aaggggattc gcagaaaaat ccgtgactct cctgcgctta tctcgtcccc
    93901 atcgtcctcc atggcgaaac cggcagtgga tcaggatccg gtggaatcgg ggtctcttca
    93961 atcgtcagcc cgctcggagc gctcggccgc gaggctgatc cccgaacatt cgcgcctgac
    94021 gctaacaacc cttcccgcct caactgccgt tcgaccacgg gtgccacccc gacatcctcc
    94081 ggcggaatcg gcgcgcccaa gaccccgcac cccgccagca agatgaacga tacggtcgcc
    94141 aataaggcgt gtggctgaat ggccgcgcgc cttgcaccgg cggacatcat cccttcagcg
    94201 ccttttcgag ttccttgatt ctcgcttcaa cacggcgccg cgccgtcccg ccgatctgag
    94261 cttttcggtc gatcgcgcct cgcactgtca gacaattcaa tacatcggcc ttaaagtgcg
    94321 acgaaaatcc ctgcaactct ttaagcgtca accgttgaag cggccgccgc ttctccagtg
    94381 agaatcgcac aatctggccg gtaatggaat gggcctcccg gaacggaacc cccgtcgtca
    94441 cgagataatc cgccagttcc gtggccaaca tgccaccacc ttcggccgcc tcagccatga
    94501 cgtcccgatt gacggccagc cgccgcacca actcggtgca cagcaccagc gattgtccgg
    94561 tcgtatccac ggcatcgaac aaggcttcct tatcttcctg caaatccctg ttgtaactca
    94621 gcggcaggcc cttcagcagc gtcagcgtcc ccatcaaatg gccatacacc cgcccggttt
    94681 ttccccgaac caactccggc acatcaggat tctttttttg cggcatcatg ctgctgccgg
    94741 tacaaaaggt atcgggcagg tccacgtagc gaaactcctg tgaggcccag agaatcaatt
    94801 cctcactcaa ccgcgagaga tgcatcatga tcagggacaa tgtactgagc acttccacca
    94861 cggcatcacg atccgacaca gcgtcaaggc tgttttgggt gaccgacgga aattcaagca
    94921 gcgcggccgt ataccggcgg tccaccggat agttcgaccc agccagagcc cccgacccca
    94981 ggggcatgac attgagccgt tggcgacaat cgtgcagccg cgtccgatcc cggtccagca
    95041 tttcgacata ggccagaaaa tgatgggcca aaagcaccgg ctgcgcacgc tgcaaatgtg
    95101 tgtagccagg catcacgaca tcgaggtgcg cccgcgcctg tcccaccagc acccgtcgga
    95161 attcctgcac ctgcttcatg aaggtggaca acacatcgcg caaaaacaac cgcagatcca
    95221 gcgccacctg gtcgttgcgg cttcggcctg tgtggagttt tcccccgaca ggtccgatca
    95281 gctccgtcaa tcggcgctca atcgccatgt gaatgtcttc atcctgcggc gagaagggaa
    95341 accgcccgcc atccagctcc accttcacga attgcaagcc tcgcacaagc tgacccgact
    95401 cgcggccagt cagaacgcct gcccgctcga gggttttgca gtgggcgatg ctgccttgga
    95461 tgtcataggg atacagtcgc cggtcgtagg cgatggatga ggagaattgc tccactaaac
    95521 ggtccgtttg ctcggcaaac cggccacccc aggccttccc tttgggcaag gcccggccgg
    95581 accgttgcgg agcacgcgcc gacttgcgcc cgcgagcgcc gacaggtgtg gatttcccca
    95641 ttacctgccc ggcctcttct tacgttgtgc gcgaatcgcc aagcggagtg cgttgagacg
    95701 aatgaatccc tcggcatctt tctgccggta cacatcgtct tcttcgaacg tcgccatgtc
    95761 caagcgatac aatgagcgcg gagacttccg tccaacaacc gtacaggtgc ctttgtacag
    95821 cttcacccgc acagtgcccg tgacatcttt ttgagcctca tcaagggcta cctgcagcat
    95881 ttcacgctcg ggggcatacc agtatccgta atagatcagt tcggcgtagc gcggaatgag
    95941 actatcccgc aggtgcagca cttcccgatc catcgtcaac gattccaagc cccgatgcgc
    96001 tgcatgcaga atggttccac cgggcgtttc atagacaccg cgtgacttca tgccgacgta
    96061 gcggttttcc acgagatcga cgcgaccgac gccatgctcg ccgcccaact tgttcagatg
    96121 ccccaagagt gcggccgggc tcatcttctt tccgtccacc gccaccggat tgccggcgac
    96181 atattcaatc tcgacttcac gcgccttggc cggcgcgcgt tccggcgaaa ccgacatgac
    96241 gaaaatttcc tccggcgggg cctcccacgg atcttccaga atgcccccct cataactcgt
    96301 atggaacagg ttcatatcca tgctgtaagg cttggccttg gtcgcggtga cggggatgcc
    96361 gtgcttctcc gcatattcaa tcaactcccg ccgcgagcgc atcgtccatt cccgccacgg
    96421 cgcaataatc ttgatctggg gatgcagcgc catgtatgtc agctcgaacc ggacttggtc
    96481 attgcccttt cccgtcgcgc cgtgacagac cgctgcagcg ccttccttgg cggcaatctc
    96541 gatttgccgc ttggcaatga gcggccgcgc aatcgacgtg cctaacagat agctcccttc
    96601 gtagatcgca ttcccacgca acatgggaaa cacgtgatcc ttgacaaacg tctcccgcaa
    96661 atcctcgaca tacaccttct tcacacccag ggactgcgcc tttttcttga tggccttcaa
    96721 atcttcgcct tgcccgaggt cggcgcaaaa ggccaccact tcgcagccat agacttcttc
    96781 cagccatttg agaataaccg aggtatccaa tccgccagaa taggccagca ccactttctt
    96841 gtacgacgac tgactcatac cactcctttt ccttacgtct tccgtgcggt tttctttccg
    96901 aggagcctga ccaaaatcgc cttctgcatg tgcaaccggt tctcggcctg atcgaacaca
    96961 accgactgcg ggccatccaa tacctcggcg ctgatttctt cgccgcgatg ggcaggcagg
    97021 caatgcatca ccaacgcatc gggcttcgcg catttcaaca ggcgcgcatt gagctgatag
    97081 ggcgcaaggg tcttgaggcg cttggcctgc tcccgctcct gtcccatgct gatccagaca
    97141 tcggtataga ccacgtccgc atccttgacg gccacagagg ggtcggagcc gatttcaatg
    97201 accgcccccg tccgctccgc ttcggccaaa gacagctcca caatacgccg gtccggctga
    97261 tagccgggcg gacagcccac cgcgatcgtc atacccatct tggcggcagc ttcgatgagc
    97321 gaattcgtga cattgttccc atcgccgaca taggcgagct tgaggccctt cagccgtcgc
    97381 tttttctcct gaatcgtcaa cagatcggac agggcctggc agggatggtt cagatcggta
    97441 aggccgttaa tcacaggaat gctggcttcg cgggcccact cttccgcgat ggcatgatca
    97501 aacgttcgca ggacaatcgc gtcgaggtac cgcgacaaca catgggccgt atcggcaatg
    97561 ctctcgccgc gggacaattg gatgtcgccc atgggcaaca ccatcgcctg gccgccgagc
    97621 tgattcatgc ccgcctcgaa cgacacgcgc gttcgggtcg acggcttctg aaagagcaac
    97681 cctagcatgc ggccttgcag caggggatga gagacgccgc gccgttgttt gactttcagc
    97741 tgggccgcga ggcgcagcaa tccggtcagc tcgtcggtgg gaatcgagag caaatccaga
    97801 aaatctttcc cgaggccggt ccggggagtt gaccgacgaa gacgccgcaa catacgcgcc
    97861 acgacacaat taatgggttg aagtggttcg ttgactcaaa atttgtgaga gcgaggccag
    97921 gaggcgatcg atctcgcgct ccgttatgat gagcgcgggc acgaaacgca gcacccgctc
    97981 tccaacgcag ttgatcaata accctcgcgt cagacaatcg gcgacaaccg ttttgccgtc
    98041 gacgtccaat tccatgccct gcaacaggcc catgccgcgc acctctttga tgcagcgatg
    98101 ccgttctttc aaggtcgcca gcccttttgc caaatactcg cccatccgcc ggccctggtc
    98161 cagaatcttg ccgtccagca agacccgcaa taccgcgagc gcggacgcac aggccaaggg
    98221 gttcccgccg aacgtcgagg catgggttcc ggggccgaag gcacgagcga cgctgtccgt
    98281 cgccaggcag gcgccgatcg gcactccgcc gccaaggcct ttcgcgaggg tcataatgtc
    98341 cggctgcatc ccgaattgct cataacaaaa gagggtaccg gtccggccga tgccggtttg
    98401 cacctcgtcg aaaatcagca ggacgtcacg ttcccggcac aattctcgga ggccctgcag
    98461 gtagccccgt tccgccacat gcactccgcc ttcggcctgg attggctcca gcatgatggc
    98521 cgcagtcttg ggcgtgatcg ctcgttcgag tgctgacaga tcattaaacg gcacatagga
    98581 aaagcccggc atcaacggag caaatccctt ttggactttg tcttggccgg tagccgtcag
    98641 cgtggccatc gtgcgcccgt gaaacgagct cgtcatcgtg atgatctcgt gacgatccgc
    98701 gccatatttg tcgtacgaat actttctggc cagcttgatc gccgcttcat tcgcttccgc
    98761 gccgctgttg cagaaaaaca ccttctgcgc aaacgaatgt tcgaccaggg tctgggcgag
    98821 ccgcacttgg ggctcggtat aatacagatt ggaggtatgg agcagatgct gcgcctgttt
    98881 ctgaatagca agcaccagat ccggatgtcc atgcccgagc acattcaccg caatgccggc
    98941 cacgaaatcg atgtactccc ggccctccag atcatagacc ttcgagccac gcccccgcac
    99001 gatcgaaatc ggctgacgct ggtaggtatt catcaggtac tgttcggcat tgagacgcaa
    99061 ctcacccgtc ggcatgacac acctctccca tcgtgagtcg gcgaagctat catagggcac
    99121 aggtgaaagc aaccgaacca gcgcctattc gcggctccca gcgcggcggc gagatgaatc
    99181 gctcggggtt tcacaggggc gtcccttgac gggaagagat ggcggatggg ataaggggac
    99241 gatatgaaaa cctgctcgca atgccggcaa gaaaaccgtg acgatgcccg cttttgtcat
    99301 cagtgcgggg caccttttgc gctcgaggct cgcgctgccg ccagcgagac agagcaggac
    99361 gcgccccaga cagatacaga actgttgaaa gccttcatcg gccccaatgc cgaccggtac
    99421 ctggaaacct tcaaaaaatt ctcaggcccg ggcggaccgc aattcgcatt gagctggcac
    99481 tggccggcct tcgtgttcga gccatttctc tggtttctgt accggaaaat gtatgtgtac
    99541 gcgctcatct atgctatcgg cccggccatg gccttttaca tcacccagga cttgtccgcc
    99601 gacatcgtct ggcgggtcat tgcgggaggc agcgccaact acatctattt ctggcacgtc
    99661 aaggaacagc tcgccaaaat taaaagcgag cgggccacgg ggggagaaac ccgcgagcag
    99721 ctcttaggcg aattgggtgg cgtacaaccc tatgtcgtgt gggtcggcgt cgggctgctc
    99781 gtgctgaaaa ttggattggt cgtcgcgatg tttaaagagg gcccgccgga tggaccgaaa
    99841 ggcccgcctg caaaaccgca ccccgccagt ctgacgcacg tctaaaccag cagcgggctg
    99901 atagaaggct acacttccga gatctgctgc cgctgccact cgatccagga cacgaaccag
    99961 tcaaaatcct gctgatacgc tgctccgctg aggtcgggcg ccgcctgcgt ctgttctaac
   100021 tgggtatagg tgcgaggcca gttcttctgc caccacgact tcagctcgtc cggcccgtag
   100081 ggctgtccgt tagggttggc gatcccggca gccgcgcaga gaccggccac caatggccaa
   100141 tagcgatcct tccccagccc aaggctgcgg aagtgctcgc gcaacagaaa gaccacccac
   100201 aactcggcac tatttttctt attgtgctta aacggctggg tctgacgtaa gggaacggga
   100261 tcgaatgtct tgatcactga ggtgtaatcc ggccccccgt agcttccggc cgattccgca
   100321 atcccctgca gcatattggc tagttcgacc tccaccatcg gtggtctggc agcctgcggc
   100381 tcagcaacgc cggcactcag tggattgctt gccgtcaaca gttcgatcag cggctttagt
   100441 tccctcaagc gtactgcggc ggccttcaaa atctgttcgg attccagcca gtagtccggg
   100501 tcacccttgg aagcccgttc ccgccctgga ggcggaagca cgacgggaat ccagtagcgc
   100561 accagcacga agaggatata ttccacctcc ccgccgacct gcaccgcacc tgccagggcc
   100621 tgacttgccc ccatcgcgcg acggaaaaac gcctcgacac gatcctcaac ctgcaggcgg
   100681 cgtcccatct cctgccacca ttgctgcaag gaagaccagt ccgaagggga aacatccggc
   100741 atcgcgacat tccacgggtg agaaccttac aggggaaacc ggcggcatgg tactgactgc
   100801 cacctttgat tgcaaccgag gtactcggac cgggctctat gtgcgaaaca agagagcttg
   100861 acagggtgaa ggggaaatcg cataacctgt cgcgacaggg tcatatccct tcggacaagg
   100921 agacgaagca cgatgagcaa actggttctc attcgtcacg gcgagtcgca gtggaatttg
   100981 gaaaaccgtt ttaccggctg ggtagacgtc cccctctcgc cgaaagggat cgaggaagcg
   101041 aaagcagcgg ggaaaaagct ggcaggattc accttcgatc gcgccttctc ctccgtcctc
   101101 gctcgcgcca acgaaaccct gcgcttcatt ctcgaagcga tcggacagac gaccattcct
   101161 gttgaaaaag acaaggcgct gaacgagcgc atgtacggcg aacttcaagg gctgaacaag
   101221 gccgagacgg ctaagaagtt cggagacgag caggtcaaaa tctggcgacg cagttacgac
   101281 gtgcgccctc cgggaggaga aagcctgaag gatacggcgg agcgggtcct gccgtattac
   101341 gagagccgga tcaagcccta tgtactcaag ggggaaacca tcctgatcgc cgcgcacggc
   101401 aacagtctgc gggcgctggt catgcagctc gaacagctga cccgcgaaca ggtgctggaa
   101461 ctcaacattc ccaccggcgc gccgttgctg tacgaactcg acaccaacgg gaaggtgcag
   101521 tcacaccgct acctgtgaca acattcgccc taggcgccgc ggcaaacagc tcgaagggtg
   101581 cggcttacac acactggctc aggagttctt gatacttatc cagcggcacg agatcgggaa
   101641 gtaggaccag caacttcggc cgatcttcgg gttgaatcaa cccttcggtt tcaagcagat
   101701 ctgagatttc ttcggatgcg gcgatagcgc cgccctcgta atcacccacc ggcgcatatc
   101761 gggcgcggcg ggcttcgacc tcgtcgagat actcctccca tttcagcgcc ccgagtttgt
   101821 actcggtctc ccaatcggcg cgaatcagat ccatcacgcg atggaacacc aggtcacggt
   101881 acttccgcgg aatgtgcgcg ttgatagccg ccaggaccca gtagagcgta aaggacagca
   101941 gttcgcgcgt catggcatct tcatgcgcgt cctcaccctg aatcccatag tcactcaaca
   102001 tctctacggt aatccggcgc ggcatcagtt tatacaaggc atccgcggct tcagccggtg
   102061 tcatggattc ttttttcatg cccatcctcc ctcaggaggg caggatactg gagcccctga
   102121 cggattgaca atactaagat gcgggcgccc tggtcaccct tgcttgtccg cagcaagggc
   102181 ctatgctaca tacacccacc acctatagct cgtaggacta tgacatacgc tcgacgtatc
   102241 cgactttttc tcgccggcct tgccttcatc ggatttcttt cgccttgcgc cgcccaatcc
   102301 gccgatccgc aggagccgca ttggggcttt gcgaccgatc tcgggctctg gaccggcacg
   102361 acgaacaaca cgacctttgc gttgggattc ggtctcgatt actacatgga ccccaatttt
   102421 tcattcggcg ggatggccct cttcaccccc gtcggtgatc tcacgcaaat cggcgtggcc
   102481 ggcgtcgcca aatatcatct ccgcctgaac agtggattca acctcgtgcc ctttgccgga
   102541 ttgggtattc tgcatgccga tctgaatcgc ggcagtggac ccgggaagat cgatcgcaac
   102601 gacaccagtc acttcattcc cctgggcatg tctttggaat accaagtcgg accgaagatc
   102661 gcgttctcca cgaccctcat ggtgaatctg caccacatca ctctctcgcc gcccgtccca
   102721 aacgacaaca ccagcgtcgc gttgctcttc ggcatccgct gggggccgta ggcttaagcc
   102781 cctcacactc tgcccaatcg gactgcacaa caattgactg ccggttagag gacaggcggg
   102841 gtcgcatcaa gaatggccgg gaaaattttc atctcctccc acataggctt gatgactgaa
   102901 gagggatggc ctcgatttcc ccctcttgca agaacactct acctaagaac tctgcgctat
   102961 cttcgaaagg cccatccgcg atgcatgctc catggcgtca ttgaatgttc ctgatttgca
   103021 gaaagagaaa tagacaactc gatccaatga tccgaaactc gcaaaacccc gacctctcct
   103081 tcaacctgat ctgtgcaccg ctttatagga tgcgcatatc gacaaagtga agcttttccc
   103141 gacaaagaag ggatgagaaa cctattccct tcctgctgtg aatacaccgg cacgtagaga
   103201 taaaggtcgt cctcaccgat cataaaggga aagaataccc cgtgcgaatg acgcagatga
   103261 aagatgtcta gattcccctg attcgaaaca tccacatgcc atacggaaac gcagccaccg
   103321 agcatgagca aacacaccac cgacagggga cgaagtatct gcatcattgt agtgatggga
   103381 cgatcgacca tacgctgcat ctgcgccaga ttagccgagg ggtgggactt cactgtacgt
   103441 aaccgttgcc tcgcataata gaccgcgttg cataaatacc tgggcaccga ttctaacagg
   103501 ccacgactaa gtctcacggt agcggaagca cgctcctctt gtaaaacgcc aactcttcag
   103561 caaagccacc gtcacgactc acggcttcga aaaggttgga gcagccgctc aaacgggttc
   103621 caagcgaggc cgcagcagag cgaggaggcg aggtgtaccc ttgcggtacg ttgagtctct
   103681 gagcgagacg agaacgaagc tggggagacg tttcagcggc tgctctggcg gatgttcaaa
   103741 cgggtcttgc tgcaaggccg cagtgagcga aaagctgagg cgtaccattc gagtacgtcg
   103801 aagttttgag caaaacgaga acgcagcagc cagcccgttt caacatccgc tacgcggctt
   103861 gggcaggacg ccacctgagc cccacatgca gcaattcctg tagcaggtct ttgtaggcga
   103921 ggttcgcttt ttcggcagag tcggcaaaat cttcaccact ggcgatctga ggattcggat
   103981 tggcttcaat cacatagacc gtccccgctt ggtccatccg catgtcgatg cgcgcgtagc
   104041 cgctcagtcc taacgcacgg tagacgcgtt tggccagatg ctgaatatga tcgatcactc
   104101 cgtccggcaa attcctcgct tcgcatgaac ggatcccgta tttgtcctgg tacttgcggc
   104161 tccatttcac gcgttgagtg gcgatgcgcc gtgactcatc cggcatctta tccatcacca
   104221 gttcccagac cgggaacact tgcaagtgcg cgttacccat cacgccgaca tacaactccc
   104281 gcccttcgat ataccgttcg acgagggctc cggttccgac attgtcgtga atgaaggcca
   104341 cccgctcgcg caacttcgcg tcatcgtcga caatggaggc ttgcgaaatg cccagcgacg
   104401 cttcttcggt gatcgacttc acaatcaagg ggaacggcag atatttggga cgacgcacca
   104461 tgcggtgaag cggcacgacc ataaactccg gatagggaat ccgatggtag gacatcactt
   104521 gtttggctaa cgccttatcc ctcgccagca tgagtccgcg cgggttgcat ccggtgtaag
   104581 gaattcgcat caattcgaga taggagacga cattctggtc gtacaccgcc acgccgtcga
   104641 actcttccag tagattgaag gcaatgtgcg gtttccaatc ctctaccgcc gcgcgaatga
   104701 cttccaggtc acttttcaca ccgagcgcct gcacgtcatg gccaagtttg cgcagagtcg
   104761 agaccacgtc atactcggtt ttccacgcgg cagtgtccag atcctgaccg ttgagttgct
   104821 ccggcggaac cagatcctta tgcatgagca cgagtacgcg cattcgtctc ataacgccac
   104881 cttatgtctc ccgctgtgca ggtaattcat ggtctgcacg gtcagcagga tcgcaaagtc
   104941 gagtttggcc tgctccgtct gttgcgtcag atgcaacttc gacgcatgac accgttcgat
   105001 catgccttct aagacttgat cgatcgtgta ttggtactct cccgtccact cagccacccg
   105061 gcggcggatc tccttcctcg ttcggcgaag gaactcggcg gcgctgggat ttttggcata
   105121 ggcaactccg gccgaaaaca atttgttcag gtccgtgtcg taggaggagg cccggccgat
   105181 tccgtagtgc tttcgctttt cctcataatg gtcccgcagc gtcttgtaga tgcgcggcag
   105241 cggatcgagt tgttgtcgac ccgtgaccat gggcgccacg ccggcgagtt cacccatgag
   105301 ccgttccatg aaatccagtt tcttcaggac cggccaacca cggtagcgct ccttccagag
   105361 cgaccccgca tccagccaca cggcaaacgt ttcggcaaag tcttcatccg gatggctctg
   105421 ggcataccag acatccaggt ggcggacgaa actccggcta tagggtctcg gggtgtagta
   105481 ttcgggatag ggttgagagg agcggccgaa gagtttctgc cgacggcggc gacggcgcag
   105541 caagaacgcg ttttcaatcg catgcccggc ctcatggcgc aggatgcgca tgcaccagtc
   105601 gtgagttccc ccttccactt ccaacatctg gctggcttcc agcttggcca accgcgggtg
   105661 cgcaaggtaa aacgggacgg caatacccgg taccccgtct ggcgtaaacc attcatccga
   105721 gagccagaag tgcggcctga agaccaatcg gcgcgcgtcc aattcgcgat acagttgttc
   105781 gatcggctcc tgatagaagg tgccgtcgag gcgcagatcc agatcgcaca tgcgaagatc
   105841 gagcagctgt tcgtccgtcc actctgccca gaccggcacc cgaccgcccg gttcagacct
   105901 ctgtcgtcga tgaatctgtg tccgccccat cgtgcaacca ccaaaaagcc ccgtccggcg
   105961 cccttttgtt ctgtttcaac tatagcagct cgcaagaatt gtgctgcccg atcactgggc
   106021 gagtcacgtc gaggctcagg gaaaaccctc ggagcggtga acgccgcctg gtgataatga
   106081 cgggacgtga ttcacgccgg cgtctaaaat tgggaatcgt ccgtaggaat cgctgaattc
   106141 ccgcgccacc ctcgatgagc attcggccta tcccattcgc gccccttctt gagctagaat
   106201 gcctggccat gcagccgacc agcacaaaac ccgttccagc ccctgcgcgc ccagccgcac
   106261 aatccgaaga gatcgaacgg gtggaaaccc gcctctgccg tctcgcgggc caagccattg
   106321 cggactatcg catgattgag gatggcgata aggtgatggt gtgtctgtcg ggggggaaag
   106381 acagttacgg actcttggaa attctgctgt cgctacgcag ccgggccccg attcacttcg
   106441 acatcattgc cgtcaacctg gatcagaagc agccgggatt tcctgcccat gtgctgccgg
   106501 agtatctcac tcgccgcggc gttccttttc acattgaaac gcgcgacacc tattccgtcg
   106561 tcaaacgatt gattccggaa gggcagacca cctgctcgct ttgttcacgc ctgcggcgcg
   106621 gccatctcta tcggctgtcc acggaattgg gcgcgaccaa aatcgcctta ggccatcatc
   106681 gtgacgatat tctcgaaacg ctgctgttga atcttttctt caccggcaag atgaaggcga
   106741 tgccgccgaa gttgcgctcc aagagcggcc gtcacgtggt gattcgaccg ttggcctatg
   106801 tgaaagaggc ggacctggct cgctatgcgg ccctgcttca gtttccgatc atcccctgcg
   106861 acctctgcgg ctcgcaggag gatttgaaac gcaaacaggt caagcagatg ctgcaggact
   106921 ggaatcagcg ttttcccggt tccaacgaca gcatgttcgc cgccctgggg aacatcgcgc
   106981 cctccctgct cctggatcgt tcacttttca atttttctga cctgaaagcg gacgccgcct
   107041 cccctgacgc ttctgtaagc gatgccgagg aggatctgct atagctgtag atctgtgacg
   107101 cgccgcagtt ccagcatgga accagcgcta ggtatatcac tgtcgcaggc cacgcaacct
   107161 tcgctggaca tgtgaaggaa aaaacagggg cagaaggaac gatcagacgc gctggcgaag
   107221 atgggttcgc cgaccacatc gcaaacaacg gtagggatag tagccgatca ggaaaaagaa
   107281 aaaatccagc agcccctgac ggcgcgaacg ttttgtatac ccggagcact taccgcagta
   107341 cgacatatcc cccactcact tgcgcaaagg ccagatggac aaccaaggga gaatcctact
   107401 gaaagaccct caggcgatgc aagtcaagtt tccacgacag gcccatcgtg ggtagccgga
   107461 cacctatggc aagtccgcac accctgtctt catttcgaac aagacgcatc tcctcgcggg
   107521 catcaggtgc ggcggcgcaa gcggaagcgg tagagacaca gcgtacatcg aaacggatag
   107581 aagccgatca cacgcatcac gaaatcgcgc caaccatgac gggtcactcg cttggcgcta
   107641 ccagagcaca ttggacaata caccatggag actgtcgtca cgcgcctttc tccttcgcat
   107701 cgggtaagat gaccccggtg cgggggcgtg agtgtgaaac agtttccacg tggaagcaag
   107761 tcctatcgca tgggggccat ccgcgagtat gaacccggtt caacagtccc ctcggcaggg
   107821 agccgagccc ccgctgtggt ccattgcggc cgcagcagcc gtgatactgt tgacgccgat
   107881 gctgctgttt tcgctcgccc ccgacgggcc gattcgcgat ggcgacacgg tcttttccac
   107941 cggggctcat aaggtacctc tgtttaaacc ggagcaacac cgtcaggcgg gatatgacgc
   108001 aacctgtctg cttgatccga aagatccgat gatcgtcctt cataccccgg cggaggggtc
   108061 ggatgaagaa gacatcatcg cgcaggtcca aggcaaaaac acgattgaat ggccgttttg
   108121 tcctccgcag gctgagctca ttatcaaacc gtaccacgtc acccagcagc ccagcatgat
   108181 caaagatctg cgagacggct tcctgaggct cttcaagtct tcctagccag accgcggagc
   108241 tcagggcttc cgcaacgcca gaaaccgctg gcggaatttc gcgactttcg gcccaactac
   108301 atacgtgcaa tagccttcga gaggattgcg ggcaaagtac tcctggtggt aggactcggc
   108361 ttcaaaccac cgagtcgccg gcaccacctc ggtgaccacc gggttgggat acagatgctc
   108421 ttgagtcacg gccgcgatca tctcctgcgc ggcctgctgc tgttcaggcg tatggtagaa
   108481 gatcgccgat cgatactggg tgccgacatc gtttccttgc cgatttcgcg tcgtcggatc
   108541 gtgaatcacg aaaaatatct cgagcagatc tcgaaagctg accacggcgg gatcaaatgt
   108601 cacacgtacc gcttcggcat gccccgtccg cccgccgcac acctgttcat acgtcggctc
   108661 atctatctgc ccgccgatat atccggattc taccgattgc acacccttga cctgatcata
   108721 gactgcttcc agacaccaga agcagccccc cgccagggtc gcaacctcca tccccgcctg
   108781 cgccatcaac gacctcgctt tcgatgttga tccaccatct acgcctgccc gccgttccac
   108841 cactcacggc cttcgcgccg caacagcgcc tcggcttcag gcgggcccca ggttccactc
   108901 tgataattcg ggaaggccgc tgatccgggc agagatttcc acacatccag aatcatctgc
   108961 acgacggacc agcctaattc aatattgtcc gcccgttgaa acagcgtcgc gtcgccggcc
   109021 atagcgtcgt ggagcagcgt ttcgtagccg gtttggggcg cattcccgaa atagtcggcg
   109081 tactgaaaat ccatattcac ctccccgatc cgcaccgtgg gaccagggac cttggcatcg
   109141 aaacgcaggc aaatgccctc gtcgggctga atgcggatga cgagcacatt cggcgccaaa
   109201 cgatcaactt gggtcttgcg aaacaacatg aagggcgctt gcttgaattg caccacaatt
   109261 tcggtcaatc gccgggtcat tcgttttccc gtccgcaggt aaaacggcac tccggcccag
   109321 cgccagttgt cgatgaacag tttcatcgcc acaaaggtct ccgtcgtcga ttcggcgccc
   109381 acatgcggct ctgcgcgata cccgactacc ggcttcccat cgaccgcacc ttcgccatac
   109441 tggccaaatg ctacaaaacg caacacgtca agcgaactga gcggcacgac tccgcgcaga
   109501 actttggctt tctcgtcgcg cacggcatcc gcggcaaaag agttcggcgg ttccatcgcc
   109561 aggaagcaga gcaactgaag gagatgattc ggcaccatat cccgcatagc acccgcctgc
   109621 tcataatacc ggccgcgatg ttcgaccccg aggctctccg ccaccgtgat ttgcacgtga
   109681 tcgatatacc gccggttcca taacggctca aaaatcccgt tcgcaaaccg gaacaccagg
   109741 atgttctgca cggtttcttt accgaggtag tgatcgatcc gataaatctg ccgttcctgc
   109801 agcactcgct gcaattcatg attgagggct tttgccgaat ccagatcatg cccgaacggt
   109861 ttctcgatga tgacgcggcg ccaggtgccg tctcgttcca cggtcaggcc gtattccccc
   109921 aggtgcgtca caatccgacc gaacaggccg gggatagtcg ccatgtaaaa aatataattg
   109981 ccctgcgtcc cggcggaagc atcgacccct tgaagcaggt cgttcagccg gcggtaagtc
   110041 gccccttcct ggaaatcccc ggccatgtaa tgtacacgct gtgagacggc ctgccatacg
   110101 gcgcgatcgg cgttttccgg cagatactcg ggcatgagtc gatccagctt cgcgcgaaat
   110161 tcttccgtcg tcgtttccga gcgatccaaa cccacgatgg cgaattgttc cggaaggaaa
   110221 tgccctgcca tcaggttgta cagagcaggc agcaacttcc gcttggcaag gtcgccatcg
   110281 atgccaaaga tgatcatgac gcagggcgtg cgtagctgtg caaggtccat gaaaggatcc
   110341 tggttagttc cgagattgtt gtggggacat acggtatcct gcctgatccc tcccctaacc
   110401 gcaaccaccg cacagtctcg ttgagatttt tttggtgagg acgtcgtgga atctgacacc
   110461 tgatcgtgcg gatccgctca tgcagcacga cgtcttcgcg ataatgaacg cgcatgacgc
   110521 ggctgactga atggccggca cgcgtgtcag agaagagttc gggccttcaa ctcagacaat
   110581 cgtcacgagg agatcgtttc ggaagagaat gtcacgatgg gacgagtgag cgtgttcgcg
   110641 aaagacaggc gcaattggcc aacggcgagc gaccgcagcg ttaattgttc tgggtgcgct
   110701 tcaaccagtc gatgaaccgc tgcaagcgcg catgctcttc gtcatgcaca tgcacaaaca
   110761 ccaggccgaa gcccgtggca ttcgtccatc gcacctccgc gacttcgacc gtcagcggtt
   110821 catacggcgc ggggaattgg acatgtagcg acaagttggc gcgcatggga agcgactctt
   110881 cgctcgtgac atggcagcca tccttggaaa gactggtcac aagcccgctg ccgtcgatgg
   110941 cgtggccgga gaatgtgagc ggcaccttta tttcatagcg tggtgtatcg cggcgctcca
   111001 cgggaacctt tcatccgatg ctgctgtggt ggtcgattcg agaaacgtcc gctgatggat
   111061 acgctcttcc gcccatgaaa tcaaccgcct ttcacgggaa gggaccggat ctgccttctc
   111121 tgcctcgctt gccagcccta cggtctacgc gttccagcaa aaaggccctg gcaaggagtc
   111181 cgcggggaac cctcctgcca tcagccgcat accaaatccg gccgggcgct cggccttggc
   111241 cgggaaattg atcgattgct cagtctttct ggctaaagtt cgggaaatac cctaccgaaa
   111301 aggtctgtac gccctcagga gtagagggcc caaggcaagg aggccttcac atggacacgg
   111361 atcttcgttc atccactcgc gtcaccgtta cctatcccgt caggctttcc ggcgattcga
   111421 tgatcggaca gggcacggtc gtcaatctct ccgcccccgg ttgcgccatc gaaacgacac
   111481 ttcccgtccg acccggcgat tatctcgaat tacacgtcat ggcgccggac caggcccgac
   111541 cgctgaatgt ggggctggcc aaggttcgct gggccactga gcaaaaggca ggcgtcgaat
   111601 ttatccgcgt gcgccgggac gaacaaagcc gacttcagcg attgatcggc caggtcctcg
   111661 aagagtcggc catcggatct gagcgggaca gacaggaatt gacggctgcc tgatcggcac
   111721 ggcaaggcca gacatggccg ccagaccttc tctcgaaaaa gtgacgatga tgtgcgggaa
   111781 agttgagaag gtagcagtcc gaatctaatg cccgccggga tcaccggcgg gattcgccat
   111841 ccgcttgatg atgattttcc gccctacggt catgagggtg aaggaaatcg cgaaggcgat
   111901 cggaacgaaa atcgccgtgg ccacgttggc attcttcacc catcccatct cgtaacaggc
   111961 cttcagcaca tagctgccca gccccgtgag atagtacgtg atgacgatca cggacagact
   112021 ttccactgtg cgctgcagga tcgcctgagc ccgcgtcgta gaatccacgc tggccaacag
   112081 cttcatattc tgatcctgca gttggatatt ctgctcctgc aaccgcaact cgatatgcgt
   112141 gcgcagcacc gccacggtcg cttcaaaatc cttctccatg gcatcgatgc gacggagcag
   112201 ctgctggtag ccgtcggtca ccccggtgat cttccaactg acgtactctg aaatttggcg
   112261 cagcggggga taaggccgct cctgcaatgc gaccaggttg ctctggacga tgcggtcgta
   112321 cggcaccgag gcggagaggc ggtatcgcat cgactctgcc agccggctca cctgcaacag
   112381 gtcttgggtg agcaccgtca gccatttctg catcgtcggg ggattcgtcc cgcccaattg
   112441 ctcgatcaac accgcccgtt gatagaggtg gcgttgctca tagtcatgga tttgatcgac
   112501 ggcccgcgaa aatgccttca tcggcaacat gactaagtgg taataatttt cgatggcgac
   112561 gatcgtatcg acaatcttcg ccacctgttg ccgaagcgcc tgctccgagg tagagcaaat
   112621 caagtaccgt tcccggtcga actcatcggg cgtaaagctc gtcaccgcga cgatgtcgtc
   112681 tcccagaatc cgactcccgt acaccatggc gccgggaagc cgcgccggca gttcgcgatc
   112741 aagcggcaac tcctgcggca ggaacagaag atcgagcgca ttcacgcgca gcccgagggg
   112801 acacaacggc atctgatagc cgggaaacgt gatcggcccg aaatcgagcg gcgtgttcga
   112861 gtcccccacc acatgccaga cctggtaact gtagtactcc gtgtgcgcct cccacacgac
   112921 gacgagacga tcgccgttgg gcgccgtctt gaacccgtag ccaaaccgct cctcaatggc
   112981 tccttccgaa atttcgaggg cctggaggag atgctgaaat tcccgccggc tattgggccg
   113041 ttctaccggc ggattcgcca tccggtaggc gacatgatgg atgtgcgccg gcacgccgag
   113101 ccattgcggc aggtactgct tattcgattg atggatccgg ttcaaaaacc ccggggggcg
   113161 ggaatgcgtt ccggtcgact cgacagtatc cgtcatatca cctctgtctc ccactgaacc
   113221 cggcccaggg cgctgccgag cctctccaat ccgatcgccc ctcgtgacga ggccggcatc
   113281 ggagacaggc ggcagaggcg aatggaacgg acttcgtcat tactcgtctt cctcttcgat
   113341 atcttcaatg ccttcgtaac tgacatcgcc ctcgtggatg gacgacgcca tcttttcaca
   113401 ggctgattca ataatctctt cggcctcctc gggagagtcg gctgaaatca aaaacttcac
   113461 ggtaatccca aagcgctggt tcacaatcgt actccttcgg cgaaataggc ggcagaaagt
   113521 ctgtcgcctg ctgtggctca ataccataag ctcccgcgta ttgtcaccct tctgtcgcaa
   113581 gaggggaaac ccgcacgtga ttcatcggcc ctgacaacgg tcagaaaagc agaactgcgg
   113641 cttcgaaaga ggcgttaacg gaccgtcagg atggacgggc gttctctgaa ggacggagag
   113701 ggtgcgatgg ggaacctgct attgagcaaa ggccgctgga aggagcaact cgccgaaacc
   113761 tggccccggc gccccgcggg cgggcgccgg agactctcgc ctatttgcgc agcaacatat
   113821 ggccgcgccg attctgttga taacacactt cgtcatggtc ggcacagaag gggcgatctt
   113881 tgccgtagga cacgatcgcc acctgcttcg cactcacgcc catgtcgatc aaaaagcttc
   113941 tcgccgcttt ggcacgtttt tcaccgagga caagattgta atcatgggtc ccacgttcgt
   114001 cgcagtgccc ggagatcttg aggagggcct taggattctc cttcaaccaa ccggcattga
   114061 cggtgagcga cgccacccca tcattgtccg acacgttata acgatcatac ccgtagaaca
   114121 cgtcctggag gccggcttcc aacgcggccg cttcttcacg ccgaatttcg gcggcccact
   114181 tcgcgtcctg ctcatttgac gtcaacatac tgccgatcgg gctccggctc aggcgttctt
   114241 caccggcgat ctggccgttc acgagaggag aaaagccgcg caactttccg ccttccgtat
   114301 ctgatgcgtc gttctgctgg gatgagccgt cctgccggcc aagtgaggga tactgtccgt
   114361 ctcgccccgc ctccccgcgt ccatacccgc ccgacgcacc ggatgacgcc gacaaagacg
   114421 aacccgaatt ggaggactca tccgagccgg actgaaacca cttcatgccg ctacagcccg
   114481 gtgccgttaa caggaccatt gccattccgc ccaacatcag ttgcgacgcg ccacggtact
   114541 tcatgaacct tgctccttgc gagggggtgt aacctgtgct gttcgtaaca aatatagcac
   114601 cggcctcgat ttacgctggt ttcagcgcgg agcctccaga aatactcggc attccgtata
   114661 gttatatcgt cttggcaatt cagtattcag ccccctccag cttcatattc tcttcatttc
   114721 ccaaggattc cgagtaaaaa cgcagcgagg tacgtagccg ctcggagggt tagacagcta
   114781 gaagccttgt acgggagaga gtcagggtcg agggagttac tgaggtggag acgctatggc
   114841 gtaagcgtac acatgtgtgc ggagagcggc acacactctt ggtgcgcccg gagggacttg
   114901 aacccccaac cctcggatcc gaagtccgat gct
//
LOCUS       DAOQPD010000004        98201 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_65_length_98201_cov_21.899273, whole genome shotgun sequence.
ACCESSION   DAOQPD010000004 DAOQPD010000000
VERSION     DAOQPD010000004.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 98201)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 98201)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..98201
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_65_length_98201_cov_21.899273"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(271..630)
                     /locus_tag="PK063_01920"
     CDS             complement(271..630)
                     /locus_tag="PK063_01920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HMZ95821.1"
                     /translation="MVHIKRIYSEPDPQDGIRILVDRIWPRGCTKERARLNDWQKELA
                     PSTALRTWFGHDPRKWKEFRSRYLAELAQPAQRRAIEELVALARSQTLTLLFGSSDVK
                     HNQAVVLKELIDRAERE"
     gene            955..1224
                     /locus_tag="PK063_01925"
     CDS             955..1224
                     /locus_tag="PK063_01925"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95822.1"
                     /translation="MIRQSGFPSDDVIDNQILVLLHRHRRLTFLTLADALPLYTWQSL
                     FAALNRLRTQEQVELLPLAADYEVIWRSGRETEPLLSKGGHLQVR"
     gene            1221..1586
                     /locus_tag="PK063_01930"
     CDS             1221..1586
                     /locus_tag="PK063_01930"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95823.1"
                     /translation="MMRVSCPAVVRCLVLVAACQMPACGNTASVFDLETNDPRQDQEK
                     IAEFYAHEATRLRQMAQDYDHRVAVYERLFGPHSDWVEGTRLLSQSYEAAAQEQERIA
                     ARHQRLHDRRSHAADQESR"
     gene            1615..2520
                     /locus_tag="PK063_01935"
     CDS             1615..2520
                     /locus_tag="PK063_01935"
                     /inference="COORDINATES: protein motif:HMM:NF013324.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005743 - mitochondrial inner membrane
                     [Evidence IEA];
                     GO_component: GO:0035632 - mitochondrial prohibitin
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HMZ95824.1"
                     /translation="MWRYTTIGLIIAGLCGLSGCGNTVSPGQRGLRWYPLTEGLTTET
                     LKSGFYWRAPWNDVYVYDVRLQSYTELVDALSSDDLLVKLKAAIIMRPIAEEVYFLAQ
                     EIGPDFYPRVVRPELLAAVRSVVSNYPMVAVPEMSAEIASKVQAVVVEKLKGRHLEVH
                     SVALADIELAKIVLEAVERKQAKEQEKEQKEFELVIAEKEAEIARRRARGEGDAIRIR
                     SEGEAEGLKIRALGQANAQQTITKTLTPEYLQYKLYDSPNAKMVLLPDQLRVPILINP
                     DQDRGTRSTPESLMRTEQELMGRGR"
     gene            2558..2791
                     /locus_tag="PK063_01940"
     CDS             2558..2791
                     /locus_tag="PK063_01940"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95825.1"
                     /translation="MACSRCQGLMVDETLFNPSEGVSHTWVPVVRCLNCGNLEDALIR
                     LARGISGRLGRRTRPGPQRRGVWSEEIRGRQKE"
     gene            2862..3275
                     /locus_tag="PK063_01945"
     CDS             2862..3275
                     /locus_tag="PK063_01945"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ95826.1"
                     /translation="MEGYGKRVLIADDEESVRRLVAIVLEQAGYIVHAAVDGVEGLGE
                     MKKRRFDAVISDFHMPRLDGEQFLLLCRLMWPDIPVVLLSAELLELPAALKQQGACIL
                     VSKPFSPQMLLQALHESLSLPESEQASDRITSKAS"
     gene            3599..3928
                     /locus_tag="PK063_01950"
     CDS             3599..3928
                     /locus_tag="PK063_01950"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95827.1"
                     /translation="MKTLLSHACVILAWSTLAGCVATSVREPFPALSDASVMGMTRGP
                     SESRLQWHEDAQELRTFADRHEVEAEVLLQHPVPTDARLIQQRRALARQLRAAADQID
                     KRADEMP"
     gene            4026..4301
                     /locus_tag="PK063_01955"
     CDS             4026..4301
                     /locus_tag="PK063_01955"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95828.1"
                     /translation="MNDGTDRNDGYDVDSAVWAYLQRCRICSMEELFRHVPTFTANQL
                     FLTVDRLSREGKVVLRYRNRAEYVMVRTGIADEWPHEMSGAPFGDRT"
     gene            4313..4558
                     /locus_tag="PK063_01960"
     CDS             4313..4558
                     /locus_tag="PK063_01960"
                     /inference="COORDINATES: protein motif:HMM:NF022603.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2934 domain-containing protein"
                     /protein_id="HMZ95829.1"
                     /translation="MKKKTAPKKAATRTTKQVAKPAVSEKQPGPVQDIQVRIAARAHE
                     LYEQRGCLDGYHLRDWLEAEREILGHPVEMDKSSERI"
     gene            complement(4643..6463)
                     /locus_tag="PK063_01965"
     CDS             complement(4643..6463)
                     /locus_tag="PK063_01965"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HMZ95830.1"
                     /translation="MAVSRKTASATVSSRRSTTSREFADRWDLADLVADPVKQFDRYL
                     KDLTAKVTRFEAARPDLSATMSEQSFLNLLTLSEQIARDSGRLGAYSYLWFSEDTKQL
                     QARSFKTKVEEHLTSLQNRLLFFDLWWQSVDEKNAERLMANSGDFRYHLETIRRFKPH
                     TLSEPEEKIINIKNITGQSAVHQLYDVVTNGFTFTLRIGGKNKTMNREALTAYLRSPK
                     AAMREAAYREMYRVYESQQDLLGEIYKTLINDWKAENLQLRHFKTPLASRNLSNDIPD
                     SAVEALLAICMKNAPIFQRYFKLKAKLCKISTMNRYHIYAPHRAEQKSYRYPDAVRMV
                     LDAYYGFSPRLAELAQRVFADRHIDARMKAGKMGGAYCYSVTPNVTPYVMLNFTGEAR
                     DIATMAHELGHAVHAMMAEQHNVFTFHSTLPLAETASVFGERILSDALMASESSKSVK
                     QSLLVNQLDDIYATVMRQAYFVAFERTAHDMVAQGATTNDLAGTYMTLLKQQFGKSLR
                     VPQEFQWEWLTIPHLYASPFYCYAYSFGNLLVLALYRMYQEQGAAFVPKYLDLLAAGG
                     SKAPQAILAQVGVDMNSHAFWQSGFDAISGMVDQLEETMR"
     gene            6618..6947
                     /locus_tag="PK063_01970"
     CDS             6618..6947
                     /locus_tag="PK063_01970"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95831.1"
                     /translation="MTEQEINRAIQYVTAATSYGRDTVAEILRTGLSELSQLSTQSTR
                     RFEREDLMGYLCQWTMKRTGHPEPLVREVLDGAGRWLDEVATTLAEQREAEANAGDDD
                     ETGAASA"
     gene            complement(7019..7339)
                     /locus_tag="PK063_01975"
     CDS             complement(7019..7339)
                     /locus_tag="PK063_01975"
                     /inference="COORDINATES: protein motif:HMM:NF024299.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ95832.1"
                     /translation="MPNPRIEPLKRVLAMEPDDDVAWFGLGKAYMEDANFEEAAKALR
                     QCITVKPTYSAAYYALAQSLLKLNRVEECRQVSDQGIDVSTKNGDAMVTKNLELLKSS
                     LPAA"
     gene            7469..8413
                     /locus_tag="PK063_01980"
     CDS             7469..8413
                     /locus_tag="PK063_01980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histone deacetylase"
                     /protein_id="HMZ95833.1"
                     /translation="MGRTGLVYDPRYLAHDMGAGHPESPNRLRAIMQRLEQSGLAAEL
                     TRLAPRTAEDEWITLVHRPEYVGHLNREAPTSGRVSLDADTSMSPGSLLAAYLAAGGA
                     LSGVDAIMADQVQHVFCAVRPPGHHAEAGRAMGFCLFNNVAIAARYAQKRYGVQRVLI
                     VDWDVHHGNGTQHSFEADPSVLFFSTHQYPHYPGTGRATECGTGAGEGFTINVPMEAG
                     EGDDDYRAVFQKVLVPAADAFKPELVIISAGFDAHRDDPLASMGLTEEGYADLTSIVA
                     GIATRHCRGRLLSSLEGGYNLTALAASVERHIRALVAS"
     gene            8410..9684
                     /locus_tag="PK063_01985"
     CDS             8410..9684
                     /locus_tag="PK063_01985"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95834.1"
                     /translation="MKWWLKLLLGLAVISGLVYLYYTEVKPVVIFGLRSEYAHAIPFQ
                     KIPEGLTSLKAESCGQCHREIYEEWKTSIHAHAYEDPFFQAYWKKDKQVWVCLNCHTP
                     LENQQPTLVKDIPRGRVEKATQEPNPHFDAALQKESITCAACHVRDGVILGPFDDSAA
                     PHPTKFDPTFRTAQFCSRCHNVVSGPAQFYNVGPCGTYAEYEGKYFMQERGFICQSCH
                     MPEVDRPVAENGPIRRGRRHLWRGGHDPDMVKRAAAIQVKVDPPKPKPGDQVTIALTL
                     TNAGAGHKLPTGDPDRHFTVEFTVKDSNQQILAEKSHTMGRWIMWQPAIVELYDNRLL
                     PLASREYQFAYRMPEASKGVTLKARVRYHILTDGQHEMLKKKYGLMADDPYAFTVYER
                     EVPLNEQLAAAFADPLPEPPPMACANPSAPQG"
     gene            10419..11312
                     /locus_tag="PK063_01990"
     CDS             10419..11312
                     /locus_tag="PK063_01990"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF012790.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HMZ95835.1"
                     /translation="MQHPLLIDCETLQTRLGQPGLVILDVRGRSTYEFGGHIPGAVHS
                     TWHEYSDPEAIAKGLLDPDVKRIEKRVQALGINRDNEVVIYSNPFDNWGDEGRMFWML
                     EYLGHKNIKVLDGGWVKWIHERRPFEHGAVRPTPGNFTVSPVASAIIMKDELKGIVRK
                     PHPTTTIVDARSLEEFLGKEVSGIPRPGHIPGAVHVAWSGFLNADATVKDLDAIHAQL
                     ELKGLNPAHETVCYCTGGVRSGWLYFVLRLAGFERLRNYPGSWWEWSRDFACPVEKDL
                     LALQKLLGLSESQVPTGMRPS"
     gene            11393..11749
                     /gene="smbP"
                     /locus_tag="PK063_01995"
     CDS             11393..11749
                     /gene="smbP"
                     /locus_tag="PK063_01995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="small metal-binding protein SmbP"
                     /protein_id="HMZ95836.1"
                     /translation="MQTAMWRGVVVAGVMMALVGAPMVSSVAFAAGNKHQAEAVEHAK
                     EAVAHGKQGHADALVKHAEAALKHAEGAMAETKNPHVGEAIKGLKDGIEHGKAGHADV
                     ATKAVENALPHLSEGM"
     gene            11831..12625
                     /locus_tag="PK063_02000"
     CDS             11831..12625
                     /locus_tag="PK063_02000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006807 - nitrogen compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrilase-related carbon-nitrogen hydrolase"
                     /protein_id="HMZ95837.1"
                     /translation="MMRVGYLQGDPVFGEVAHNLDTVTAQLEHAEADLLVLPELFATG
                     YQFTSQEEVSRLAEAVPDGPTTQRLLEIAARRKTTIVAGLAERAGTKYFNSAVVVGPK
                     GFIGCYRKTHLFFEETLFFNPGDSGFQVWDIGAAKIGVMICFDWYYPESARTLALLGA
                     EIIAHPSNLVLPNCPDSMVTRCLENRVFSVTANRIGSEARGGKDRLTFIGLSEIVSPR
                     GQILHRAPRDREELTIIEIDPAEARRKALNSYNDLLRDRRPAMYGV"
     gene            12690..13250
                     /locus_tag="PK063_02005"
     CDS             12690..13250
                     /locus_tag="PK063_02005"
                     /inference="COORDINATES: protein motif:HMM:NF014659.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgE/AlgH family protein"
                     /protein_id="HMZ95838.1"
                     /translation="MTTPLTKGVLLVATPALNDPNFRQAVVLLCEHGPEGALGVIVNR
                     PTAMSISEALPQVPILEGQPHVLYSGGPVQTNQVMMLYRISDTPENSHQVFDGVCLGG
                     DLEIMERILMEQPGKESFRAYLGYSGWGPGQLESEMQTGSWITLPADPSIVFEKEAAR
                     IWSDIVLSLDETSRHYADMPFDPSSN"
     assembly_gap    13444..13543
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<13544..15702)
                     /gene="uvrA"
                     /locus_tag="PK063_02010"
     CDS             complement(<13544..15702)
                     /gene="uvrA"
                     /locus_tag="PK063_02010"
                     /inference="COORDINATES: protein motif:HMM:TIGR00630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HMZ95839.1"
                     /translation="MPEHRESGLQVVLDRLVLRPDNRHRLIEAIEVAFQEADGVCQVD
                     VIGHGLRTYSTHFRCQGCGRTFEPLRPLLFSFNHPLGACPECKGFGNILRYDRDLVIP
                     DRSKSLAGGVIEPWSKPGSDWWQKQLLLAMKKLEVDLTAPFQELPSEVQQLIWEGSDQ
                     VEGVRQYFDYLETKRYKLHVRVLLSRYRSPATCPICQGSRLKPAARFVKLAGHDFIQL
                     NDFTIQAATEWFQRLALPAFDAEIAKDILRQLQAKLNFLLRVGLNYLTLSRQTKTLSG
                     GEAQRIALANQLGSRLVGTLYVLDEPTIGLHARDTDTLAGILRDLATEGNTVVVVEHD
                     PLMIQAADHIVEMGPASGEQGGQVVCAAPRAPFIRDPKSLTARYLRGEERIPLPKTRR
                     SGNGKVLSIAGAAEHNLKNLLVRIPLHMLVCITGVSGSGKSTLIEDTVYRAAARAFRI
                     ESLPMGRFQAIKGLEYLKGVRLIDQQPIGRTPRSNPITYLKAFDEIRQLFASERDALR
                     QGLTPGHFSFNAAGGRCERCEGNGYEKLEMYFFEDIYATCEQCNGRRFKPEILAIKYR
                     GKTIHDVLNLTVTEAQAFFSGSPKLTEKLYLLSSIGLGYLRLGQAANTLSGGEAQRLK
                     IAAELKDPSAHNQLYILDEPTTGLHLDDIKKLLAVLHKLVDAGNTLIVVEHNLDVIKT
                     ADWIIDLGPEGGEAGGQIVAEGRPEQVAKVAQSHTGR"
     assembly_gap    15708..15807
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<15808..16460)
                     /locus_tag="PK063_02015"
     CDS             complement(<15808..16460)
                     /locus_tag="PK063_02015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014449886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95840.1"
                     /translation="MASRTPPTRSTDELIIEGARQNNLKNISLRIPHNKVTAITGLSG
                     SGKSSLAFDTLFAEGQWRYVESLSTYARMFLDKVNRPDVDRITNIRPAIAIEQKNPIR
                     TARSTVGTATEVADLLRLLFAKIGKPVCPDCHQEARGYHPGSLAEELLAQFPDARAMI
                     LFPVNDLGPGHDRSLLDSLTKRGFTRLRCGDEILDLHDNITLPEHRESGLQVVLDRLV
                     "
     gene            16612..17442
                     /locus_tag="PK063_02020"
     CDS             16612..17442
                     /locus_tag="PK063_02020"
                     /inference="COORDINATES: protein motif:HMM:NF012995.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylamine N-acetyltransferase"
                     /protein_id="HMZ95841.1"
                     /translation="MVDRSAYLARIAYEGPVDPSIETLRRLHRAHVLTVPFENLDIHL
                     GRPISLEPLDLFRKIVTGKRGGYCFELNGLFALLLEDLGFAVTRLAARVLYGAEGVRP
                     RSHELLLVQLGETAWIADVGFGGNGLLEPLRLMDGYEERQGADRFRLLAQEQGGYRLQ
                     WEMESVWTDLYSFALDPWLPIDFAFANYYHSHSPDSLFMQRRICTMPTLKGRKTLIDN
                     LLKIRSSNGTQELHVKSEGERQALLQQHFGVTINDHLRFCDLPRQPFHDRNAGHVEAE
                     "
     gene            complement(17389..17727)
                     /locus_tag="PK063_02025"
     CDS             complement(17389..17727)
                     /locus_tag="PK063_02025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3147 domain-containing protein"
                     /protein_id="HMZ95842.1"
                     /translation="MGDWAKYGLYFLLGGTIVSISTYLGSQGRSFLAAFASTFPAMTG
                     ATFVLIYLNGGNEHLVTYAKNLLWFVPPWLVYVGCMIYGVERIGFWLSMAGSLGLYMA
                     CVAIVKWLAR"
     gene            complement(17740..18759)
                     /locus_tag="PK063_02030"
     CDS             complement(17740..18759)
                     /locus_tag="PK063_02030"
                     /inference="COORDINATES: protein motif:HMM:NF002558.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95843.1"
                     /translation="MNPSFSSYLVNDVFGDPGLFVEVRWSKRALLFDLGHNDALGPTR
                     LLRASDIFISHTHMDHFIGFDALLRVALGRGKTLRRHGPPGLIPNVQGKLHGYTWNLV
                     DGYPLTITAHEFHPDGIQTATFLATDGFQRHDEPDAPLNGCTGQGPFTVFRDPMFTVQ
                     ATALNHRIPSLAYALQEQFHVNFNKERLHEAGLPVGYWLKEVKQYFWEGQPDDFRFCA
                     TLYHEHHKETREFILGEIRERFVTITRGQKIAYVVDARYDEVNERKIIELARGADIFY
                     CEAPYLDRDADKARDRYHLTAKQAGIMAKKAEVRELVVFHFSPRYTGLGHEIEAEARE
                     AFRGQ"
     gene            complement(18847..19530)
                     /locus_tag="PK063_02035"
     CDS             complement(18847..19530)
                     /locus_tag="PK063_02035"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95844.1"
                     /translation="MIRPEEASAAYPIQHNERGAALALLPLIATLLYYASPRELRQEP
                     LYQFLPQLCAYAALLTWSRLNGATVTRLGLTRALIPRGLRLGIATGLALGTANVLVIL
                     YLVPWLGADYRFLAGTPHAKIPLLLMLPWFILMIAAMVELNFRGFLLGRLLGLGLPSA
                     LAVPLSALLFAFDPFLVATFQHLHWIAVWDGLVWGSLWVAFRNLYVTIVAHAVEVIVL
                     YSVMRTILT"
     gene            complement(19537..21087)
                     /locus_tag="PK063_02040"
     CDS             complement(19537..21087)
                     /locus_tag="PK063_02040"
                     /inference="COORDINATES: protein motif:HMM:NF014385.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HMZ95845.1"
                     /translation="MTNPMLRGCLLIGGATALLLWTASTSFGLEVTKPVPTERREAMS
                     LADAVLKALQNNLDIHIGRQTKESRLADIIIEQAKFDPTISLNGQYNRQVAPLNRPIL
                     GFTGANLQDITKFDQNTSSVTADITQNLPTGANYDLNYSPQRSYVSGPNTFLFNPAWT
                     GGLALTVTQPLLRNFGTDVNRTFISIAQNNATVEQHVFLDRVLTVIATVEQTFWEMVF
                     ANENLKVAQAALKAAEELLASNRAKAKAGVMSIVDVLQAEAAVASRVEQILVAEKSIR
                     DQEDQLRRLLNPAEEELRQDLRLMPTDPPTTSLEAISLQEAIDIAMERRPEVLQAGKN
                     VESSDLNVKFAKNQLLPTLSVQGTMGLSGLGADYGDATRRNFGGDFYNYGAGLVLSYP
                     IGNRSAYSTYNKRQLESRNAQASLQSVRQQVIVGVREAVRRVHTDFKRIETTRSARIM
                     AEKQLQAEQERLKVGLSTTRFVLDFQRDLATAQGNELRATVDYNKSLSNLARNKATTL
                     ERYSLRLE"
     gene            21136..21594
                     /locus_tag="PK063_02045"
     CDS             21136..21594
                     /locus_tag="PK063_02045"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95846.1"
                     /translation="MMVAWYHKRRSVSMLARKGRATMRSTGIMLVAVTAALLWVSPAA
                     AQSVSGVRGFNGGVAPLFGLVGPGNLYIDNQGTQGFIYNFGNNFESYNFRNPTTGQAW
                     SGAVMTLGPQLSVGLIQGANQSGSPVVFPPVPRETAPLPPIQSGLLEDIP"
     gene            22146..23219
                     /locus_tag="PK063_02050"
     CDS             22146..23219
                     /locus_tag="PK063_02050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HMZ95847.1"
                     /translation="MRIAQVSPLWESVPPKLYGGTERIVSYLTEELVRQGHEVTLFAS
                     GDSVTKAKLESPCQQALRLNTGIFNREAPLIQMMEQVFAAADQFDLIHSHLDFLAFSL
                     SRRCRVPVVTTLHGRLDLPELVPVFRDFAELPLVSISDSQRRPLPWCNWANTVYHGLP
                     KDLYKFNAEPGKYLAFLGRVSPEKCPDQAIELAKRVGLPMKMAAKVDPADRAYFERVV
                     EPLLDHPLIEFVGEITDAEKSDFIGNAIGLVCPYDWPEPFGLVLIESLACGTPVLAYR
                     RGSIPEIIGHGVTGFISENLDEMVSQVSKLGTIDRHRCRQVFDERFTAQRMTNDYVKI
                     YQQLIADAATLPGKAGQQHASNL"
     gene            23253..24533
                     /locus_tag="PK063_02055"
     CDS             23253..24533
                     /locus_tag="PK063_02055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HMZ95848.1"
                     /translation="MADESQSTPESNVTGWRLLATRDFGCLWAGQVISQIGDGLNKVA
                     LLWFVYEMTGSALKMTAIGLLQTIPPLVFGPLIGVYLDYLPKKTVMIVVDLLRTLMVL
                     LIPLFYALDLLTLERLYVLVFLVSIVSTIFGPALASAVPLIVQRSQLTTANAFLQSTT
                     NIGVLLGPAMSGLGIALIGAQNVLYVDAATFLLSALFLFPIRVRETKSVKELDVLGTP
                     VMQDMMVGFRFVFLQHRVVFALMITAVLYNLAISAFVFLLPVVAKELLQVGPMELGWL
                     WSALGIGMLAASIWLARMPQGTFQERIGKIGRSLTIGGLAVCALGLIQTPVLFSTFLL
                     IIIIGGSTSLFYPVVWAMLQEVTPEHLLGRVFTTFSVGGMASAMVGMAGFGWAADTLG
                     PAVSLIGIGLLLLLTAMVTMQVSRRGLVVTPAVA"
     gene            24735..25763
                     /locus_tag="PK063_02060"
     CDS             24735..25763
                     /locus_tag="PK063_02060"
                     /inference="COORDINATES: protein motif:HMM:NF016836.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BON domain-containing protein"
                     /protein_id="HMZ95849.1"
                     /translation="MPMRTIQTVCVAGILSFVVASGLGSVRSMASEPQPSETKPDVAP
                     GSGSKDAEGKIKEPDTKPKEPESKPKEPEAKPTDQKSKDSDTKAKEPEPKAKDGEAKP
                     KGQEPKAKESTTKPKESEHKAKEGESKSSKEPDQKSKEPEAKPKDAEIAAEHPCPSVP
                     QAADAKPQVEAPVPSGDSGTGERQKSEPEPKKPVRSSMVTAKLALMADPHLFPYDIEV
                     DAKDKDLVLLGKVGQESDKRVATDIIRCLEGVHAVENRLKVEADAAHGLFAERDKIIT
                     QLVKERFEKSKTLQSVKFDVKTEDGVVTLNGATRFQIIVLEAAQAARQVPGVRAVNTD
                     AVRLVAGE"
     gene            25819..27162
                     /locus_tag="PK063_02065"
     CDS             25819..27162
                     /locus_tag="PK063_02065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HMZ95850.1"
                     /translation="MEPGRASGTGPGRPNVKWSPHLLTRDFTLVWWGQMVSQIGDGVS
                     KLALLWFVYSITGSPLKTTMIGLLQTLPPILFGPFIGVIVDRVPKKLLLISSDLIRAL
                     VLGVLPCLLPVDSFSIERLYLMVFVHAVASAVFGPALTAAIPSLVSRHEFTAANALLQ
                     TTTSIGIIVGPALSGVGIATMSSQEVLCVNAVSYVISALCFLLIRFPRTETVPAAEGG
                     SLAGTLRDVMEGFQYVLHRQRVILMLIGAASMYTFATSAFSTLFPVFGKKLLDLGPIE
                     VGYLWSAFGVGLLLVSLGLVSLSSWSLPKRIQLMAVSSFISGLTLLGLLFTSNRLVAA
                     VLMVIIGMGAGTLTPVAWGVLQEIAPTTLLGRVLAIYNLGAMTSAIAGMTIFGWVTQE
                     FGERPSVFGIGVGLFLSAVVSWRVARWVQVNWSETSVPAEEAARSVVMVTQPTSH"
     gene            27303..29468
                     /locus_tag="PK063_02070"
     CDS             27303..29468
                     /locus_tag="PK063_02070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amylo-alpha-1,6-glucosidase"
                     /protein_id="HMZ95851.1"
                     /translation="MEEIISVNDQFYILASSSMADDRTRVLKHGETFGVFDRYGDIQP
                     VGRGTQGVFHQGTRFLSRQEIFLNNDRPMLLSSTVKEDNALLAVDLTNPDLYRDGRIA
                     IPRGSVHVFRSRFLWNGVSYERFRLSNYSLAPVKMTLSIRFEADFADIFEVRGKKRER
                     KGRMLPNILRKDLLVLRYEGLDEVTREARIQFVPEPLEITASQATFGIELEPKGEIAV
                     AVLVACDEVDSHRPLLSYDAAMAEAGLAFGAEQTEDCTIQTSNAQFNEWWNRSVLDVR
                     MMVTDTSEGPYPYAGVPWFSTPFGRDGVITAMECLWIRPELARGVLAYLASTQAKEVN
                     PAQDAEPGKILHETRKGEMAALHEIPFGLYYGSVDSTPLFVMLAGAYYERTADLPFIQ
                     SIWPNLEAALTWMDTYGDIDRDGFVEYVRKSPTGLDNQGWKDSHDSISHADGSLAEGP
                     IALCEVQGYVYDAKVQASKLAEALGYVDRASQLRRQARSLKERFEEAFWCEASSTYAL
                     ALDGHKRPCEVKTSNAGHCLYTGIASDEHARRVAETLMSDELFSGWGVRTLADSERRY
                     NPMSYHNGSIWPHDNAMIAVGLARYGLKAGVEKIMTGMFEVSLVLDFHRLPELFCGFV
                     RRPGQGLTRYPVACNPQAWAAGSAFMVLQACLGLSIVASEQKVIFNHPILPDFIDKMQ
                     IKNLTVGTASVDLLLRRHDLDVGITVIRRVGKVEVVSVK"
     gene            complement(29499..31040)
                     /locus_tag="PK063_02075"
     CDS             complement(29499..31040)
                     /locus_tag="PK063_02075"
                     /inference="COORDINATES: protein motif:HMM:NF016289.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M28 family peptidase"
                     /protein_id="HMZ95852.1"
                     /translation="MSAQSHHSNLVGQLILSLWIALTPVTVLAENQLEVPQSLRQSLE
                     LVSSQRMVEDVRTLSGPTFNGRQTGTSDDLASAEFVRQRFLESNSSQPPLQESRSKGS
                     PAHASIRIQSTSHRPTIIGKDSFLRLAGSADSPPDQIGPDYLPVLDSPSADVQAPVVF
                     VGYGISDPESGFDEYAGLDVRQKVVLFLRGKPERYAKQVSHADKAHAAHAHGALAYLT
                     ATGPILNAYETRRGVTGRPSAFYGLTEPDRTIPGAWISTTRAMAILHTDRTGHEDRLR
                     TLQQHLNEGQPPQSIATDTVVTMRWHSAVQDGLLHNVVLTVPGSDQAKAEETIVIGAH
                     RDHFGRQGGLLFPGADDNASGTAVLLEIARVLQAAPVQPKRSVVLISFSGEEQGLVGS
                     KFYISQPTAPLRSTLGMINIDHAAVGNGRLTIGVTGMDKAAAQQAGQMAGVADRLDVF
                     GFFPGGDHVPFKEAGIPTVTVVSGGIHPHFHQPTDTAETINPDILSEAARYVLAMLWQ
                     LADAP"
     gene            complement(31082..31519)
                     /locus_tag="PK063_02080"
     CDS             complement(31082..31519)
                     /locus_tag="PK063_02080"
                     /inference="COORDINATES: protein motif:HMM:NF028108.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5069 domain-containing protein"
                     /protein_id="HMZ95853.1"
                     /translation="MDLRQHPPRRWSDATAGLIWLPRLIDKVRAFQAGTLGAYAYPSA
                     LDQSFMRHLRLTPAQIESLVRDMTSDEAIGAALRQHIPLSTEEIQERCAAFQKKYEWA
                     FAVLDRDDGYTRGLGYPLPQFLQRPLWRWYQRWSAQKAHATSI"
     gene            31715..31960
                     /locus_tag="PK063_02085"
     CDS             31715..31960
                     /locus_tag="PK063_02085"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95854.1"
                     /translation="MAEQGKGLYDSQYARFRDNQGTHQGYEFQHGPAGSVPPPVVTFM
                     DKIKWWTLRGWRRKKILAERDRYQQDIIQIKTAHPKS"
     gene            31986..32816
                     /locus_tag="PK063_02090"
     CDS             31986..32816
                     /locus_tag="PK063_02090"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95855.1"
                     /translation="MHYGYQRVRQIQVGRKNQWGGVTSFVRALRYVGVAAVVGVLAGG
                     METAWAVPKETSTEKAEHLRQQANPQLFNDWTFDKDEVGAIPKGFVAVTSGDQRPGSW
                     KVEAQAAVPSAPNVLLGTSGCGECQEILVAQGFQYEYPDLVVRIQQGGGAATGQVGVV
                     FGMKDAQNYYATVVDVSQKIIQVVRVIEGKESVLGRAAIKPKPVEWHTLRVQRNTIIS
                     KDFVETFFDGSLALSVEDQALGVGQVGVLVRGESSARFDNFNAAPLYSSRPLSAPAAY
                     "
     gene            33106..33402
                     /locus_tag="PK063_02095"
     CDS             33106..33402
                     /locus_tag="PK063_02095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HMZ95856.1"
                     /translation="MGSKIYVGGLPYSTTEQQLSDLFAVHGAVTSARIITDKFTGQSR
                     GFGFVEMSGDSEAQAAINALNGTQFGGRTLTVNEARPQEPRSGGGGRGMGGGRH"
     gene            33550..34899
                     /locus_tag="PK063_02100"
     CDS             33550..34899
                     /locus_tag="PK063_02100"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: protein motif:HMM:NF012492.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HMZ95857.1"
                     /translation="MVSFAELSLTSFLADRLQQAGFTAPTPIQSAAIPLALQGRDLLA
                     QAKTGSGKTLAFLIPLIERAVKEGWKPAGHASAQTGSSRSPRALVLAPTRELALQIEM
                     ELRKYAPPAVTSLAVYGGVPIERHYRALRQPPMIVIGTPGRLLDVAGTRHLDLRGIEY
                     VVMDEADQMLDRGFLRDIQRILQLLPSQRQTMLFSATFSPEILTLAESMLKNPARTAV
                     DPGVNTPTTITHAYYVVPSEASRVQLIHTLLQSSEAGDQSMVFCDQKYKVKRLAARLG
                     GEPASVGAITGNHSQAQRERTLTAFRSGRLRSLVATDVAARGLDVPTVSQVIHYELPG
                     NPTSYVHRTGRTGRAERSGATLLILSPQEEHEYLAMVRRLRIQTKRLTLPTLATLPPP
                     ARETESNSHPRHDGHGRDARPRRSGDRPNSTSQDARGGQGRRGWRAGRPAAPRRGNS"
     gene            34954..35487
                     /locus_tag="PK063_02105"
     CDS             34954..35487
                     /locus_tag="PK063_02105"
                     /inference="COORDINATES: protein motif:HMM:NF012478.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HMZ95858.1"
                     /translation="MSSARNLLLSMMVAAGCLAAGEGAFAQSDLAIADGMKVSLEYTL
                     SLPDKSVADSNVGQEPITFVQGAHEIVPGLEKALDGMKAGQKRRIDVSAQDAYGPYNN
                     KLRQSIDKDKLPKDVKVGDILQASDNRLVKVLEVNDKKVLIDLNHPLAGKTLTFDVNI
                     LKVEKGDAADVPEKKNP"
     gene            35780..37777
                     /gene="uvrB"
                     /locus_tag="PK063_02110"
     CDS             35780..37777
                     /gene="uvrB"
                     /locus_tag="PK063_02110"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HMZ95859.1"
                     /translation="MPPFKLDAPFKPCGDQGQAIDKLTSGILAGKQHQALLGVTGSGK
                     TFTMANVVERVQKPTLVLVHNKTLAGQLYQEFKQFFPHNAVEYFISYYDYYQPEAYIP
                     QSDTYIAKDASINDAIDQMRHAATTSLLQRNDVLIVSSVSCIYGLGSPEVYHDMLVYL
                     EEGMETRREKILAKLVDIQYARNDVDFHRGTFRARGDVIEIFPASSEAKSVRIELFGD
                     TVDAIHEIDPLTGKSLGKLPKIAIYPNTHYLIAPDRYERAITGIEEELEARVAAFRKN
                     GQLLEAQRIEQRTKFDLEMIRAMGYCHGIENYSRHLSGRAPGDPPPTLLDYFPKDFLL
                     IIDESHATVPQIGGMYEGDYSRKRTLVDYGFRLPSAVDNRPLKFAEFEQMLKQVIYVS
                     ATPGPYELEHAKGEVIEQIIRPTGLMDPLIDVRSAKGQVDNLLAEVRAEAAKGNRVLV
                     TTLTKRMAEDLTEYYHDLGVKVRYLHSDIKTLERAEIIRELRCGVFDVLVGINLLREG
                     LDLPEVGLVAILDADKEGFLRSHRSLIQTAGRAARNLDGRVIFYGDTVTDSMRSAMDE
                     TARRRHIQEAYNVANGITPESIKKLIPVLDYASGGTNAGQLELAAESLADYAPTADTE
                     QLIRRLEVEMKAAAKKLEFERAAELRNRIRSLKLKALEFTE"
     gene            complement(37820..38080)
                     /locus_tag="PK063_02115"
     CDS             complement(37820..38080)
                     /locus_tag="PK063_02115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4321 domain-containing protein"
                     /protein_id="HMZ95860.1"
                     /translation="MRKSIGVLLIFILIGGMLGGIFGEILRVMAPNGAIQNIFASNFS
                     PGINPPLTVDLVLLKLTFGFSIKVNLLSVLGMFLGAYLYKQM"
     gene            38477..39826
                     /gene="ffh"
                     /locus_tag="PK063_02120"
     CDS             38477..39826
                     /gene="ffh"
                     /locus_tag="PK063_02120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HMZ95861.1"
                     /translation="MLDALSEKFERILKKLRGQGVLTEENIAEALKEVRLALLEADVN
                     FKVVKDFLDRVREKAIGQEVLKSLTPGHQVVKVVWDELRGMMGGERSGISLASRPPTI
                     LMMVGLQGAGKTTTSGKLARLFKSQGKRVLLVAADPRRPAAGDQLASLGHDLGIDVHR
                     FDQVDASRADVVRICQRGVERAQEQGYDLVVLDTGGRLHVDDELMAELVAVKEAVTPH
                     EVLLVADAMTGQDAVNMAGQFDRQVGLTGVILTKVEGDARGGAVLSIRAVTGKPIKFL
                     GMGEKLDALEPFHPDRMASRILGMGDVLSLIEKAQETFSREEAEAAQKKLTSSTFTLE
                     DFRSQLGQMNRLGSFEQILGMLPGGQKLKDLANSGLPEKEMKRVAAMIDSMTSRERRD
                     HTLINGSRKKRIARGSGTSVQEVNRLIKQFLQARKIAKVMSGGAGGRRQLAQMLRGM"
     gene            39927..40235
                     /gene="rpsP"
                     /locus_tag="PK063_02125"
     CDS             39927..40235
                     /gene="rpsP"
                     /locus_tag="PK063_02125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HMZ95862.1"
                     /translation="MAVHLRLARTGRHKRPMYRVIAADSRKPRDGRFLEILGIFDPLK
                     NPAVPVLKSERVLSWLRHGAQPTTTVRTLLKRHGVWKEFETEKSAKAEKPGKDEKSKK
                     "
     gene            40245..40772
                     /gene="rimM"
                     /locus_tag="PK063_02130"
     CDS             40245..40772
                     /gene="rimM"
                     /locus_tag="PK063_02130"
                     /inference="COORDINATES: protein motif:HMM:TIGR02273.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HMZ95863.1"
                     /translation="MTPLDQAELVTIGRIERSFGVRGEARVRSLSDVPGRFEALREVT
                     IVASSGKSLVTRVTHVRSGGPTLIVGFEAFTTPEQVAEFRGGLLQVPRGDSPALPSDQ
                     YYQCDLIGMVVQDEAGTVLGQLEEVLAMSDNQAFLVRQDGKELLIPAAKQIVLSVDVG
                     KRVMTVRLPEGFGDL"
     gene            40774..41547
                     /gene="trmD"
                     /locus_tag="PK063_02135"
     CDS             40774..41547
                     /gene="trmD"
                     /locus_tag="PK063_02135"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N(1))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HMZ95864.1"
                     /translation="MRCAVLTLFPDMVAPVLGQSILKRAQEKGLLEVSVQNLRDYTFD
                     RHKTADDVPYGGGAGMVMKAEPVLQAVDALRARYQASHPETALRVIMPSPQGRPFTQA
                     LAQSLAKDDRVLVFVCGHYEGMDERVNVALCPEQISVGDYVLTGGELAAMVMIDAAAR
                     LVPGVLGDAASAAEESFTEGLLEYPHYTRPAEVRGMAVPEVLVSGHHEVIRLWRRKEA
                     LRNTYLKRPDLLRDRELGLEDQRLLSEVMQESLVQVPVR"
     gene            41563..41967
                     /gene="rplS"
                     /locus_tag="PK063_02140"
     CDS             41563..41967
                     /gene="rplS"
                     /locus_tag="PK063_02140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014449694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HMZ95865.1"
                     /translation="MNRLERIQRSLTKKTAPKFEIGDTVRVHVKVVEGEKERIQVYEG
                     TVIARKGTLNSETFTVRKLSYNVGVERTFPIHSPSVAKIDVVRQGRVRRAKLYYLRTK
                     KGKFAKVEDREFKVESKAQAAAKVEAAAAAKA"
     gene            42057..42695
                     /locus_tag="PK063_02145"
     CDS             42057..42695
                     /locus_tag="PK063_02145"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HMZ95866.1"
                     /translation="MEARSRGYRHIAGLDEAGRGPLAGPVVAAAVLLPRRCRLPGLND
                     SKQIIEADRVRLFDEIVRRAIGVGVGAATEVEIDRLNILQASLLAMRRALMALPLQPD
                     FLLLDAVTLSGLSIPQRPIIKGDGLSCSIAAASIVAKVTRDRLMVEYHRWYPQYNFAE
                     HKGYATPEHLRLLREHGPCAIHRRSFAPVQHCFAEDDTVSLSLSDESESLFD"
     gene            42695..43081
                     /locus_tag="PK063_02150"
     CDS             42695..43081
                     /locus_tag="PK063_02150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HMZ95867.1"
                     /translation="MRDRRRLLGDEGEGQAEAYLRRQGYRILGRNVRSPLGELDLIAD
                     DAGTLVFVEVKRRRSGAYGGAIEAVDARKRAKLIQLASHYLAQHRLHDRACRFDVVLI
                     QDDAGSGAAVQHIANAFDVAGDDLRW"
     gene            43183..43851
                     /gene="ftsE"
                     /locus_tag="PK063_02155"
     CDS             43183..43851
                     /gene="ftsE"
                     /locus_tag="PK063_02155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HMZ95868.1"
                     /translation="MIQLFHVSKYYDRRPALSDVTLEIEKGEFVLLMGPSGAGKSTLL
                     KLLIGAERPEEGQILVQGRSLSKLRPSEIPVLRRKVGIVLQDFRLLPKKTVFENVSLP
                     LLVQGASTTEIRRKVAEALRAVGLDHKKDLFPPGLSTGEQQRICIARAIVNGPIMLLA
                     DEPTGNLDPELTSEIIELFKSINARGTTIIVATHDPNVLAQVNRRVITLEHGKVVSRD
                     QGAS"
     gene            43848..44747
                     /locus_tag="PK063_02160"
     CDS             43848..44747
                     /locus_tag="PK063_02160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HMZ95869.1"
                     /translation="MRRLLYLLREAVANVLTNRTTTLVAVATTAFTFACVGVFLLLYV
                     NLRTMASSLEQDIQVMVYLQDDLTEQARSEIEQQLKIDRAIASLTFVSKERALADFQA
                     QFPSESRLLQGLGQNPLPASFVVLMAPESRSSDAMRRWANRTQLIPGVSQVQYNQEWV
                     EALAGIVRYIEVAAIIVGVILSAASVTIIANTIRLALYSRREEIEILGLIGASTTFIR
                     VPYLLEGAALGLCGSALSLVILKGGFELFRHQIHSATRFLGVDALLTFFSFDMCLVLM
                     LVGLFLGCAGSFLSLLRFGEGRA"
     gene            44744..45940
                     /locus_tag="PK063_02165"
     CDS             44744..45940
                     /locus_tag="PK063_02165"
                     /inference="COORDINATES: protein motif:HMM:NF013700.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HMZ95870.1"
                     /translation="MTRIQWVWVVLSVHLALSTSPPPAHAERKDSYADKIEQEKKTLE
                     KLRGTIVEKRKKADEAEKKRESILQGLQSLDERLVRYRQEHQDTVRKLKKKDVEIEQM
                     SVQLSRLSERIDERQDAIAARLRVQYVEGRFWQLKTLLAASSSGDFQRRFRYLSAVTQ
                     REYEIVEGYRKDAERIAEVERSREEARQGILLYKISTEEKLAQIQGLKKQKRVYLAKI
                     TQEKESHDRAVEELERSASRVDSLLKELETRRRAALANRPPSAGAGLRALRGTLLWPT
                     DGQVVSYFGRQKHPTFNTYVQRKGIEIRAAEGSIIRSVLAGQVVYADWLKGYGLVIIM
                     DHANGVFSLYAHASKILTSVGARIEAGNAIGETGDTGMTGENTLYFELREGAEPVDPL
                     VWLSKR"
     gene            45965..47311
                     /locus_tag="PK063_02170"
     CDS             45965..47311
                     /locus_tag="PK063_02170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HMZ95871.1"
                     /translation="MEQRRSRRWLYLLLMVTVALGVGIVLEKGLERTGHASETYEELR
                     TFSEVLTQVQKHYVDDTKVKDLVQGAIRGMLSTLDPHSAYMTPEMYKEMQVETKGEFG
                     GVGIQIGVKENRLAVISPIEGTPAHRAGIKAGDFITKVNDEPTKDLTLMDAVQKMRGP
                     KGTKVNLTIQRDGTADPLAFSLVRDTIKIESVKFKVLDNTIGYVRLTQFQEATGRDLA
                     RALKQFKEQKVQGTILDLRNNPGGLLTAAVDVSEQFVGNGKLIVYTKGREGKKDEWFS
                     KTKETLEDSPMIILVNEGSASASEIVAGALQDWGRAVIVGTTSFGKGSVQTILPLGDG
                     SGLRLTTAKYYTPKGRSIQSTGITPDIVVKLQTQTVAKAGDKDAKEAEPKTAKAPASG
                     KDSASSKPADEPAHKNGAASLNDAGGDISVEDDVQLQKAVELLKTWKIFKELRPAA"
     gene            complement(47286..47777)
                     /locus_tag="PK063_02175"
     CDS             complement(47286..47777)
                     /locus_tag="PK063_02175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase"
                     /protein_id="HMZ95872.1"
                     /translation="MDDRLNQLAQIFRAMANLLAAQRANPYRVRAYRKAADAILMITG
                     DLTDLAARRQLQEIPGIGKDLAGKIEEFLTTGTIRAYEELRTPLPKEVAEWASLPGLS
                     DALVSYLYFRLNIRSLADLESLVASHLLRTQPGFSGSEDDLLAAIRRQRASDAVTPPV
                     EAP"
     gene            47909..48115
                     /gene="thiS"
                     /locus_tag="PK063_02180"
     CDS             47909..48115
                     /gene="thiS"
                     /locus_tag="PK063_02180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HMZ95873.1"
                     /translation="MTIQVNGESRGIGDGHTVAALLRDLDIRADRVAVELNLEILDRK
                     DFETRGLCEGDRVEILSFIGGGAE"
     gene            48127..48897
                     /locus_tag="PK063_02185"
     CDS             48127..48897
                     /locus_tag="PK063_02185"
                     /EC_number="2.8.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014959879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HMZ95874.1"
                     /translation="MNDRLVIAGREFQSRLWVGTGKYKDFAETKKAIDASGADVVTVA
                     VRRVNITDRSKENLLDYLDPKKYIILPNTAGCYTVEDAVRYARLARAAGVSDLVKLEV
                     IGDEKTLFPDTAGLIEAAKILIKEGFIVLPYTNDDPIVAKKLVDIGCPAVMPLAAPIG
                     SGLGIRNPYNLKIIMETVKVPIIVDAGVGTASDAALAMEYGADAVLMNTAIAGAQDPI
                     AMAEAMKYGVWAGRLAYKAGRIPRKLYATASSPIEGML"
     gene            49007..49633
                     /gene="thiE"
                     /locus_tag="PK063_02190"
     CDS             49007..49633
                     /gene="thiE"
                     /locus_tag="PK063_02190"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: protein motif:HMM:TIGR00693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HMZ95875.1"
                     /translation="MSAVDFRLYLVTDRHQTAGRPLGSVLARAVRAGVRAIQLRERDL
                     PVRDLHALATELQRELPDARLFINDRVDVALALRTVGVHLRESSLPAGVARCLLGPSQ
                     LLGTSVHSLDGVIVAEQQGADFVVLGPIYDTPSKRVYGPPLGMRILEQAAQKVRIPIF
                     AIGGITAARTREVRQAGAFGVAVLSSILSAVNVEQATEELLAAIQMES"
     gene            49883..51559
                     /gene="arc"
                     /locus_tag="PK063_02195"
     CDS             49883..51559
                     /gene="arc"
                     /locus_tag="PK063_02195"
                     /EC_number="5.6.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000502 - proteasome complex [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0010498 - proteasomal protein catabolic
                     process [Evidence IEA];
                     GO_process: GO:0019941 - modification-dependent protein
                     catabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proteasome ATPase"
                     /protein_id="HMZ95876.1"
                     /translation="MTHKNDEHAREVEKLRTQIQSMEEEIRRLYQSRYQLEQTTKQNE
                     KLVATLQEAKSQIETLRAEVEKLTAPPSTYGIFSSLDTDGTGNVYVSGRKMKVSLHPS
                     IKAKELRKGQEVILNEALNVIAVRGFDVQGEVVRLKDVLEGNRALVTLHFDEEKVAEL
                     GEPLLSERLSVGDHLLYDPRSGCVIEKLPKSEAEELVLEEVPDVDYEHIGGLQREIEQ
                     VRDAVELPFLYPHIFSNYKLSAPKGVLLYGPPGCGKTLIAKAVASSIAKKLGHLKDRQ
                     LRSYFLHVKGPELLNKYVGESERQVREVFKKAKERADDGHPVIVFFDEMDALFRTRGT
                     GISSDIESTIVPQFLSEIDGVERLTNVIVIGASNRQDLIDPAVLRAGRLDVKVKVGRP
                     DATAARDIFSKYVSTDLPFAEEDLARHGGDARALVDSLMNLTVDAMYATTDENKFIEV
                     TYANGEKEVLYFKDFASGALIEGIVSRAKKFAVKRAIAQEGSGLRADDLIRAIREEFK
                     EHEDLPNTTNPDDWAKVAGKKGEKIVHLRTISGGPSEARQIETVSTGHYL"
     gene            51574..53073
                     /gene="dop"
                     /locus_tag="PK063_02200"
     CDS             51574..53073
                     /gene="dop"
                     /locus_tag="PK063_02200"
                     /EC_number="3.5.1.119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0010498 - proteasomal protein catabolic
                     process [Evidence IEA];
                     GO_process: GO:0019941 - modification-dependent protein
                     catabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="depupylase/deamidase Dop"
                     /protein_id="HMZ95877.1"
                     /translation="MNDTHSHNLSRVIGTETEFGIASRDPNAADPVANSIHVIGYYPN
                     LPAPQAVWDYENENPLLDARGFEVDGERERPGPDYNRQLNKVLANGGRLYVDGAHPEY
                     STPECTNAREVVAFERVGERIIAQALAGITEARGRDQFVLYKNNSDGKGNSYGYHEDY
                     LVSRAVSFDRITQVLTPFLVTRPIYAGSGKVGAENQTPSVDYQISQRADFFETLVDLN
                     TMVRRPIINTRDEPHSDSTKYRRLHVIVGDANMAELSTYLKVGALSIVLDLLEAGADL
                     PRISLADPVNAIKQVSRDTQVKESLKLTDGSATTAIAVQRAYLKAAQSYYACHELNQV
                     TKDILVRWEDVLDRLERDPRLLVRELDWVAKRYLIESYMDRKSCGWDDPRVRLMDLQY
                     HDVRPDRGLYYTLERSHMIERVVLEHEIVRAETNPPVGTRAYFRGQCVKKYPNAVYGV
                     SWTSVLFDVGQNKIKRIPLMDPLRGTEALTGELFAHAETAAALLEKLST"
     gene            53087..53911
                     /gene="prcB"
                     /locus_tag="PK063_02205"
     CDS             53087..53911
                     /gene="prcB"
                     /locus_tag="PK063_02205"
                     /EC_number="3.4.25.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005839 - proteasome core complex
                     [Evidence IEA];
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0010498 - proteasomal protein catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proteasome subunit beta"
                     /protein_id="HMZ95878.1"
                     /translation="MNRMPFLPHHDGSSFFDFLTQHHPELRPGVHDLAMPRATLPLDL
                     GRPGAIPVPHGTTVLALKYRDGAIIAGDRRATEGFQIADRRIEKVFRIDEYSAMAIAG
                     AAGPCIEMAKLFQTELEHYEKLEGVQLSCEGKANKLGQMVKANLPMVFQGLVVMPLYV
                     GYDVKRKEGRIFKYDITGGRYEESDHHSIGSGGKDARNTMREHYRSGLDEEAALRVGL
                     LALYNAADEDVGTGGPDLVRGIYPTAKVVSDAGITDVPESRVRALYEAMIAERRRS"
     gene            53915..54598
                     /gene="prcA"
                     /locus_tag="PK063_02210"
     CDS             53915..54598
                     /gene="prcA"
                     /locus_tag="PK063_02210"
                     /EC_number="3.4.25.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005839 - proteasome core complex
                     [Evidence IEA];
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0010498 - proteasomal protein catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proteasome subunit alpha"
                     /protein_id="HMZ95879.1"
                     /translation="MPLPYYVSPEQMMQDKAEYAKKGIAKGRSIIALEYVDGIVLAAD
                     NPSSSLHKVSEVYDRIAFAGAGKYSEFEHLRKAGIRHADLTGYMYSREDVSARTLSNA
                     YSQSLGTAFSTDVKPLEVEILVVQVGGNGQANEIFRISFDGSIVDEKSFAVIGGRSEA
                     VQQYLREHATPQPPTLKDGLRRCLSALEQVATQKIPSENLEVAVLDRNRQGRKFRRLT
                     SADISHLLA"
     gene            54752..56128
                     /gene="pafA"
                     /locus_tag="PK063_02215"
     CDS             54752..56128
                     /gene="pafA"
                     /locus_tag="PK063_02215"
                     /EC_number="6.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0010498 - proteasomal protein catabolic
                     process [Evidence IEA];
                     GO_process: GO:0019941 - modification-dependent protein
                     catabolic process [Evidence IEA];
                     GO_process: GO:0070490 - protein pupylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Pup--protein ligase"
                     /protein_id="HMZ95880.1"
                     /translation="MQQRIFGLENEYGLIFSPNGKIYLPMEKVLGYIFEGLIPNSWPS
                     NAFLVNGARFYQDTGCHPEYSTPECDNILDLVIHDKAGERLLEACLPAAEERLREEGL
                     SGEIYIFKNNTDSLGNTYGCHENYLMRRDVDFWKVTEQLIPFFVTRQIYSGAGKVLKV
                     SGKPQYFISQRAQHIHEKTSSSTTSSRSIINTRDEPHADAEKYRRLHIIVGDSNMSEY
                     ATYLKVGTATLVLSMIESGFSVTGMELEDPVKAIREISRDPTLNKKVKLDDGRQMTAI
                     EIQRVYVKRATEFLAAQDHDPVLDDVLDKWISVLDRLEDDPMQLVHEVDWVMKKHLIQ
                     SYTDKKDCGWDDPRVFLLDLQFHDVKRTRGLYYLMENRGMAARVVEEEAVQRAMSVPP
                     QTTRAKVRGDFIRFARAKNRSYTVDWTYLKLNGYWEETILCMDPFSAVNRRVEELLSQ
                     VSGARLYR"
     gene            56161..57144
                     /locus_tag="PK063_02220"
     CDS             56161..57144
                     /locus_tag="PK063_02220"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HMZ95881.1"
                     /translation="MSFLDRFLIISVVLLASVFPVELFPNTGPVPRGGDGQFSGKQGQ
                     VVVVTVPELKEATSVKGKFLGRTVTLFPNPTAGGTGYIGLLGIDLQDEPGPHELTIDA
                     QLGEQTRHFSYQVLVVKEKFAVEHLKLPKDKVDLDEKATARWKAEQEQVRKALAEESA
                     MRLWQAGFIEPVHGKRTGIFGSVRIMNGQPRNPHNGEDIGAPMGTDVMASNDGVVRLV
                     VDHIFSGRGIFVDHGLGLYSMYFHLSEALVNEGDLVKAGQVIGKVGATGRATGPHLHW
                     GMKVNGARVNPYALLELPFPQNPAADRPVLAAPAVPAQEELAPTAVGGDGR"
     gene            complement(57194..>59161)
                     /locus_tag="PK063_02225"
     CDS             complement(57194..>59161)
                     /locus_tag="PK063_02225"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ95882.1"
                     /translation="QTVYGSGAKAREAGRIAWADQIHPEDRQSILAGLSHTLESDKNL
                     WTAEYRFRRADGTYAYVIDHGYVLRNYAGTPYRMIGAKTDISDRRQAETMHAVQLTVG
                     LALEESVSLNEAVPKILRAMCELQGWTLGALWLVDTQHSVLRCNALWHPSGQQTEHFA
                     QAYRTLFLRQDMGMAGRAWKTDAPAFSPDIVNEADFPAHDAAREADLHGAIAFPIHTG
                     KEILGIMEFFTVEVLHPAVSRMERIAELGAMISQFLNRKDLERQLRQAQKMEALGRMA
                     GGVAHDFNNLLTIINSWAELLMDEPGLTSRAQRGMAQIREAGNKATGLTRQLLAFTRH
                     QVVERQSLNLNERVSDIVELMKRVIGEDIHLVLTLDPTLGRIKADPGQIEQVVMNLVV
                     NARDAMPHGGRLELETGEVMISHSDPFWPDPLPPGPYVTLSVRDTGCGMSAETLAHVF
                     EPFFTTKELGKGTGLGLSTVYGIVRQSSGTVGITSEVGKGTSFTIYLPRLEEDTGAPR
                     AVTQPKVTSEQSETILLVEDNDMVRGLAHTVLVAQHYHVLAARSGEEALEMVRRQGRH
                     IALLVTDMVMPGMGGAQLAHELQTLQPDIKVILTSGYSGRDETLLKTFDAQVAFLPKP
                     YTPESLTKTVASALESQTRQGSCRDTSSHST"
     assembly_gap    59162..59261
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<59262..59805)
                     /locus_tag="PK063_02230"
     CDS             complement(<59262..59805)
                     /locus_tag="PK063_02230"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ95883.1"
                     /translation="MQVLLIEDNEDDAALIREALCEHSPQDVLLTWADRLEAGLLKLA
                     EGSPDAVLVDLSLPDSQGMDTLVRVRAQAHEAAVIVLTGLDNDLVAEKSLLHGAQDYL
                     VKGRLTGDGLKRAIRYAMGRHRVEQALRKSEERFHLTCLATRDGIWDWDITSGETWFN
                     DAYQTVYGSGAKAREAGRIAW"
     gene            complement(59809..60249)
                     /locus_tag="PK063_02235"
     CDS             complement(59809..60249)
                     /locus_tag="PK063_02235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ95884.1"
                     /translation="MTMRPFDILIAEDNEDDILLIREAFETVNMTNRVAVVRDGAEAM
                     AYLRGEGSFSQCPLPGMVLLDINMPKKTGLEVLEEIKSDPRFRAIPVVILTVSEREED
                     IVRSFEKGACSYIRKPVTFTRFIAVVKEFELYWTLVSKVPTLKR"
     gene            complement(60246..62999)
                     /locus_tag="PK063_02240"
     CDS             complement(60246..62999)
                     /locus_tag="PK063_02240"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ95885.1"
                     /translation="MTSNGLYGLMTDKLTPRIRELGIGAFIAALCGAMFVLDCLTPRG
                     IPGWVLYTLPIVLTTWTPHPWSSHAVAVGCAGLTYLAYVLSADVPGVPTWLPQVSRSF
                     SIVLFPLIAYVVDRQKRLTSELLKSTTMAAEHKALLDRSQLLRKTAEEVQDLYDRAPC
                     GYHSLDANGLIVAINRTEVDWLGYTKSELIGKIRFTDVMTPAGVGLFKERFPQFIKDG
                     YVNDLEFELIRKNGSTFSVLLSATAVTDSDGRFVSSRSTLIDITERKRADQALRLSHQ
                     SLEALVEERTAALQEANSRLEQELAQSKQMHQALIASETRFRELVESLPLPIWTCLPD
                     GTCDYLSPRWANYTGRSADEPFSTGCLQHVHPEDRPRITEQWHHSVAHIQPLDTELRF
                     KRADGIYRWFHAHATPIRDHDGHLLKWVGTYTDIHDRKQAQEIQARLASIVESSSDAV
                     LSKGLDGRILSWNKSAELMFGYPSEEIIGQPVSRILPPERRAEEAILIEQITAGIRIQ
                     QFESVRLHKDGHPIQVSLTVSPIVDANGEVTAVSTIARDITERKRAEEVLSQQRRLIE
                     LSYDPIFTWDFERGILDWNRGCEQLYGYTRAEAIGRSSHTLLKSTYPCPFDTICAELE
                     ATGAWTGELHHRTKDGREVLVESRWGLMKTGGRSLVLETNRDITERRQAELMILKKNK
                     DLETLLYVTSHDLKEPLRAIESFSVLLQERYASRLDEKGQDFLRRIVRATQRLDQLLT
                     DILDLSRAQRMEPPVDEIDAHQLVQEVLRRLESRIKESGATITVCTPLPRLRVNTTWA
                     VQGIYNLVANALKFVADGRPPDIEIAPHTEIDAEGTECSGLVIRDRGPGVPSDQRERI
                     FELFRRAVGREIEGTGAGLAIVRQVAERHGGRAWVLPREGGGSDFFITFGINRQVVKE
                     VGL"
     gene            complement(63198..64619)
                     /locus_tag="PK063_02245"
     CDS             complement(63198..64619)
                     /locus_tag="PK063_02245"
                     /inference="COORDINATES: protein motif:HMM:NF014069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HMZ95886.1"
                     /translation="MKLPSSTPPAPYDGSALIADPIHEYVSFTVPYATPDPSERTEKD
                     LIDSPWVQRLRYIYQLQSARWVYPSAEHTRFVHSLGTMHVAGRFARHLYPFLRNAVPD
                     LPSAAFVEEFLRITALVHDIGHGPFCHFFDDNYLHGFGLSHEKLGQIIVREHLGPLIK
                     KIRRSPSGPFDRGEELNPDHIAHVILKEKGKDNSKIPRWINVLQPVISGSYTADNLDY
                     VLRDAYMCGVAVGPVDLTRLIHYTIVTEKGFTIHKTGLPALHMFLNTRMYLYSNVYYH
                     RTTRAIDIHLRDIFGDTMKLLFPSNPAKHMDEYLTLTDWSLLEDVRRWKKAGQSSLRR
                     LHQEWAHILSRDVKWKMAYSTVLKEKGIERGMDFPSHEQFQQQIQNALPAKLRDLPFR
                     VDMAPLDPRPDPKDTRGIPLLVYDPGTKGLSTEPLEEFLDLLPTRLVQFRIYALDHAH
                     DAALSRAAATVLNKTPSSIETNF"
     gene            complement(64643..65122)
                     /locus_tag="PK063_02250"
     CDS             complement(64643..65122)
                     /locus_tag="PK063_02250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2062 domain-containing protein"
                     /protein_id="HMZ95887.1"
                     /translation="MADVRSLFRQILHLDETPHRTALAFAVGVFIGFSPAYGLHMIMV
                     GLCAWLFGWNVVALLAGAFLNNPWTLIPILGATYWTGATLLGMREFPTFDWSDLSFTG
                     LYHQVAPHAWPFVLGGMVLSIAGSLLAYPIAYVLLTRYRRARAVERATHLPPPSGLG"
     gene            complement(65145..66185)
                     /gene="thiL"
                     /locus_tag="PK063_02255"
     CDS             complement(65145..66185)
                     /gene="thiL"
                     /locus_tag="PK063_02255"
                     /EC_number="2.7.4.16"
                     /inference="COORDINATES: protein motif:HMM:TIGR01379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009030 - thiamine-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-phosphate kinase"
                     /protein_id="HMZ95888.1"
                     /translation="MPPGRTRRASTVQSEFGLIRKLRAQAAQPDPQVFKGIGDDTAIL
                     KTSSTEWTLITTDLLAEGVHFDPTTSSFRDIGYRAAIANLSDIAAMGGTPRFMLVSIA
                     IPRACSTTQIQQLYRGMTEADAPYRVRLVGGDTSASKTGLFLNITLTGVVKPRQALLR
                     SSARIGDLIYVTGTLGDSRAGLDLLTSRRRPKLRPTDARFLLGRHHRPSARIAEGLWL
                     VRHGLAGAAIDLSDGLTGDLRHICEESGVGAEIIAGSLPLSRACRAYAMARGLDPVEI
                     ALQGGEDYELLFTVPRGQQLRFERLVKKTGFRMTCIGSITPKAAGLRLRTDAGATRPL
                     PLTSYEHFRRPT"
     gene            complement(66261..68759)
                     /gene="lon"
                     /locus_tag="PK063_02260"
     CDS             complement(66261..68759)
                     /gene="lon"
                     /locus_tag="PK063_02260"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HMZ95889.1"
                     /translation="MAEAVEQDFSSNQNLEPPDQLPLLPVRDIVVFPYMVLPLFVGRE
                     MSIKAIEAALAGNRMLFLATQKSLDVENPQPEDIHSVGTVGIIMRMLKLPDERIKILV
                     QGLAKGRIEQYIQNDPYYSVKIEKLVETKQPGSTLETEAVMRTVKEQIEKIVSLGKVL
                     IPDVMVVIENLEDPGRLADMVASNLGLKVDITQAVLEIVDPIQRLRQISEILAKEIDV
                     LSMQQKIQAQAKGEMDKTQREYFLREQLKAIQKELGELDERAEEVAEFRKRIKDAKMP
                     EKVLKETEKQLKRLEKMHPDTAESATVRTYLEWMVELPWNKKSKDNLDLKAAMKVLNE
                     DHYDLEKVKERIVEYLAVRKLKEKMKGPILCFVGPPGVGKTSLGKSIARALGREFVRI
                     SLGGVRDEAEIRGHRRTYVGALPGRIIQGMKQAGTNNPVFMLDEVDKVGMDFRGDPSA
                     ALLEVLDPEQNSTFTDHYLGVPFDLTEVMFVTTANLMDPILPALRDRMEVIDIPGYTE
                     EEKLGIAQKYLIPRQMNEHGITEKHIRVSETAIRHVISHYTREAGVRNLEREVANLMR
                     KVAKKVAEGKAECHAIDQTNLNKYLGVAKFIPEAELEKDEIGVATGLAWTESGGDVLY
                     IEATVMKGKGQLTLTGHLGDVMKESAQAALSYVRSREKTLGISPDLFAKNDIHIHVPA
                     GATPKDGPSAGITMATAIASALAQIPVRRDLAMTGEITLRGRVLPIGGLKEKILAAKR
                     AKLSTVALPKRNKKDLEEIPKHILKGIELIFVDTVDDVIKAALRRAPSRKATAGAPKT
                     PLKKPSPVTASKRKAAASPRRRRALTGTTRSLSL"
     gene            complement(68846..69772)
                     /gene="galU"
                     /locus_tag="PK063_02265"
     CDS             complement(68846..69772)
                     /gene="galU"
                     /locus_tag="PK063_02265"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HMZ95890.1"
                     /translation="MTRTDVRKAIIPAAGLGTRFLPATKASPKEMLPLVDKPLIQYVV
                     EEAVASGIEDIIVITGRGKRAIEDHFDRSLELEENLKGSGKGQVLNQMRHISNLANFC
                     YVRQPEAMGLGHAVLCAQHLIGDEPFAVILGDEIIDAAVPGLAQLIHIYKQRKGAVLG
                     VQEVPQQEVSRYGIISARKVRSGLHRVEDLVEKPAPADAPSNLAVIGRYVLPPEIFPI
                     LRKTPPGKNGEIQLTDALRQLVKNTPMFAHEVEGQRHDAGDKLGFLIATVELALKNPS
                     LGPAFGDFLQQRLRPTTADVRRRGPGRGRATT"
     gene            70088..72412
                     /gene="bamA"
                     /locus_tag="PK063_02270"
     CDS             70088..72412
                     /gene="bamA"
                     /locus_tag="PK063_02270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamA"
                     /protein_id="HMZ95891.1"
                     /translation="MTKSGGRRWVPILVLVLAALFVIGEAGWVRAQVSAPLVNSVTIR
                     GQKRIELQAIQGRLTLKANDRFTPDALREQVKILYGTGYFEDVQVETETADGGVAVGF
                     IVREKPFITEIVFDGNEELSDDKLKEKITIKSQTFLDQQQAKESAEKIRLAYQEDGFY
                     NCQVIPVIQAVDEDRKRLTYFIKEGTKAKVRRINFEGMRAVTKEEVFKVTATREWIPW
                     YGLITQLKLPSLLSDAGVLKREELGNDIERIREVYLNKGYLNVQISQPTLELSDDKKW
                     FEISYSVVEGEPFIVQEVGFRGNTVFEDHELREGLGIRPGEIFQRAKIRGEITRITDL
                     YGAKGYVFADVVPNVTPDNNARTATITLNVKEGEMMRIREIHVTGNDKTRDNVVRREL
                     RLDEQDVIDTLALKRSFQRLNNLNFFETVEILPQQVDVDKVDLNVKVKEKPTGQFSIG
                     GGFSTLDKLVAIADITEGNLGGNGWLGRIRGQLGQQRSLGLVTFRNPYVNDSYNALQL
                     DIYRSMTNYISYFESKSGASATWSRWLSEYVNGSISLFGEQLKYSDPQEGLCPDLIPL
                     ICRQLGTQSSTGFRTSLFRDTRDYYLDPRTGWRLSVGADYGTPALGGSNHFYKVYFDV
                     IKYTPLVYDTRFSVHVRYGQTEGIGGRPIPLTERFFVGGINTMRGFVFGRAGPVTPSG
                     SLLGSAKELIFNNDFIFTISSEAKLNGVFFFDYGNGFDDNEPVQFNKLRSAAGFEARW
                     ISPFGPLRAAYGINLDPRPTERMGVFEFTIGSLF"
     gene            72454..73029
                     /locus_tag="PK063_02275"
     CDS             72454..73029
                     /locus_tag="PK063_02275"
                     /inference="COORDINATES: protein motif:HMM:NF015871.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpH family outer membrane protein"
                     /protein_id="HMZ95892.1"
                     /translation="MRGLVGWKSVRGAGWNGLCLALLAVTLLVGGCRSNPSTVPTSTR
                     IGVVDPQRILGETNAGKRAKDMLASFAKNRQALIELEEKELRRMEEDFVKQGSVLSAT
                     AKREREEQFRRRMAEYQQKVTDLNREVQDKQKEVLDGFRDKIESLSAKVAKRLELQAI
                     FDRGRGGPTLYFDEAVDVSSQLIEEFNKTYP"
     gene            73040..73576
                     /locus_tag="PK063_02280"
     CDS             73040..73576
                     /locus_tag="PK063_02280"
                     /inference="COORDINATES: protein motif:HMM:NF015871.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpH family outer membrane protein"
                     /protein_id="HMZ95893.1"
                     /translation="MNVRNWMAAGVLQVLVAWGAQPVLAADHLKVAMMDQQQVIERSV
                     AGKRALEELKSYSTTRQKIIDSDDQELKDLEKGMQDASMSEDARKEKQEHFRTKLEAY
                     QRRIQDFNREVQEKQRGMVAEYAQKIQAAAAAVAQKEGYTAVLDKGSESTVKIVIYSH
                     PSVDLTEQIIKEFDRQNK"
     gene            73619..74083
                     /gene="fabZ"
                     /locus_tag="PK063_02285"
     CDS             73619..74083
                     /gene="fabZ"
                     /locus_tag="PK063_02285"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HMZ95894.1"
                     /translation="MSVMDNVEIQSILPHRYPFLLVDRIRELDPDRRIVGIKNVTINE
                     PFFQGHFPGRPVMPGVLILEALAQVGGVLAFKSLGAVGRPVVYLTGIDGAKFRKPVVP
                     GDILRLEVDVLKKRAPFWKMQGKAFVDTELVCEAEVTAMVMDEKAAGEKAAG"
     gene            74210..75019
                     /gene="lpxA"
                     /locus_tag="PK063_02290"
     CDS             74210..75019
                     /gene="lpxA"
                     /locus_tag="PK063_02290"
                     /EC_number="2.3.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008780 -
                     acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine
                     O-acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP--UDP-N-acetylglucosamine
                     O-acyltransferase"
                     /protein_id="HMZ95895.1"
                     /translation="MKIHPTAVIHPKAVLADDVEVGAYSVVGEHVTIGAGTRVLSHVS
                     IDGWTDIGERCELHPFVSVGGPPQHMQYKGEPTKVVIGHDNILREYVTVNRATVQGGG
                     VTTVGHSNFLMAYVHVAHDCHLGNHLILANAASLAGHISIGDHAIIGGLSGIHQFVRI
                     GAYAMVGGCCALGQDLPPFMRAAGGYRARMYGLNSIGLRRHGFSAERIAALKKAYEVL
                     FRSGHRVAEAVKLAREQFGASQDVLQVADFMQGTKRGICRSVGKDQEGEEE"
     gene            75025..75867
                     /gene="lpxI"
                     /locus_tag="PK063_02295"
     CDS             75025..75867
                     /gene="lpxI"
                     /locus_tag="PK063_02295"
                     /EC_number="3.6.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249556.1"
                     /note="LpxI, functionally equivalent to LpxH, replaces it
                     in LPS biosynthesis in a minority of bacteria; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-2,3-diacylglucosamine diphosphatase LpxI"
                     /protein_id="HMZ95896.1"
                     /translation="MGGRAAHDSQAPEGQRIGLIAGNGRFPIIFADNAKRLGYSVFAV
                     AHEGETDPELAQHVDNIHWIKIGQFGKLIDALKGDGVQQAVMLGGIKKTHVFTTVRPD
                     FRALALAAKLIHLKDDDILRRVAEEIEQEGIRICESTFGLQGILVEAGTLTRREPSKK
                     EWEDIRYGWDVGKQIGALDIGQCVVVKDRVIVAVEAVEGTDGAIRRGGELAQGGAVVV
                     KRCKPQQDLRFDLPAVGPRTIEVMEAVKASVLALEAGRGILLDRDDTIAKANRAGIAI
                     VGMT"
     gene            75920..76909
                     /locus_tag="PK063_02300"
     CDS             75920..76909
                     /locus_tag="PK063_02300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HMZ95897.1"
                     /translation="MTALRAGVIGVGHLGQHHARHYATLPGVTLAGVYDASPDRAKLI
                     AERHGVQAWTNLGEVLTQVDLVSVAAPTSAHFAAAKACLEAGKHVLVEKPIAVTSAEA
                     HELVELAARRGCLLQVGHSERFNPIMQRMRASIERPAFIEGHRLSAFGERGTDVDVVL
                     DLMIHDLDLVLSFQPGPVEEVRAAGVPVLSSNIDIANARIAFASGCVANLTASRVSTN
                     KMRRLRFFQRDRYVSIDFQSRQAMVSRRVQGTGPRPTIDVETFQAGDEEPLRLELESF
                     IHAVATGSRPVVSGEDGEAALNLAGRVLDAIGQFTQRHSAGDVSAAAFGHDSL"
     gene            76949..78082
                     /gene="lpxB"
                     /locus_tag="PK063_02305"
     CDS             76949..78082
                     /gene="lpxB"
                     /locus_tag="PK063_02305"
                     /EC_number="2.4.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008915 - lipid-A-disaccharide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-A-disaccharide synthase"
                     /protein_id="HMZ95898.1"
                     /translation="MPRILIVTGEASGDLHGAHLVKALKELAPSLQIVGIGGASMRAA
                     GAELVKDIPQLDVMGLIGLSAVKAMLQRISRIRALIKRERWDLVVLIDNPGLNFHFAR
                     VARACRLKVVYYIAPQVWAWRRGRMRWIQQRVDHVLAILPFEEPLYKKAGVRCTFVGN
                     PILDEVASTYDREALRRQFELSDAGPVIGLFPGSRKAELLEHVPLLIETVKRLAQRHP
                     TMQFILAQASSVQDQFLADLLKDSPVPIKVLRNQASEVMAASDLLVVKSGTSTLQAAV
                     VGTPMILFYRAPSWVTYRLARLLIRVPWIGLANLVADRGIVPELIHDEATPERLAQET
                     ERLLADPRAYAEMKAALLSVRQALGTPGASRRAAEAVLAECRS"
     gene            78079..79815
                     /gene="msbA"
                     /locus_tag="PK063_02310"
     CDS             78079..79815
                     /gene="msbA"
                     /locus_tag="PK063_02310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005319 - lipid transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006869 - lipid transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A export permease/ATP-binding protein
                     MsbA"
                     /protein_id="HMZ95899.1"
                     /translation="MKHYLRLLAYLNPYRFRLGAAFVCALLVAGLSAAYAWLVRPVLD
                     GLFISKDESLLLVLPVAILLVAVLKGVFNYGQNYLMNYVGNQVIGDIREQLFSKLVRL
                     PVHFHDTNTSGRLVSRVINDVNQMANAVAGVLKDLFQQGLTFLAMIGVIIYQNWKLAM
                     VSMIVVPLSVVTMARMGKKLRGLATRGQERMGDMASTLQEALAGIRMVKSFGREEDEA
                     KRFRQSNDAFIHTTMKAIQVSSLGSSHMEVIGVLGVAGIIWYGGYLVIHDEMTPGAFF
                     SFLAAMFMAYTPIRRLSGANNTVQQALAAAERVFDVLDLPTEQVANGGQTELPQISRS
                     LEFRQVAFQYEGQGDAALKAIDLTIRAGEVIALVGSSGSGKTTLVSLLPRFYDPSGGQ
                     ILIDGVDIRNCTLQSVRGQIGIVSQEVVLFDDTVRNNIGYGRQGATIDDVMQAAKLAY
                     AHDFISRMPDGYETLIGERGLKLSGGERQRLAIARAILRDPPILVLDEATSALDTQSE
                     RIVQMALSNLMRNRTTLVVAHRLSTIQNADRIVVLDRGTVAEIGTHDELLRKGGLYKR
                     LHAMQFADALPQ"
     gene            79850..80512
                     /locus_tag="PK063_02315"
     CDS             79850..80512
                     /locus_tag="PK063_02315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HMZ95900.1"
                     /translation="MTNRSPAAPQPKQALTKRLTNALKLAVVPPVGYAVIRLLQRTMG
                     WRTEGREHVSRIFAQGQQAILAFWHAQQLMMPLAIPGLKAHILISQHRDGELICRIVA
                     RFGLDAVRGSSTRGGAEAFRRLVRLGRSGGNLVLTPDGPKGPRQVAKVGVVQLARATG
                     LPIVPMAFGCSKKNSSRAGTGSSCPIHSRRGSSSLGHRLQSRRMHPLRTWSACAGSWK
                     RP"
     gene            80562..81917
                     /locus_tag="PK063_02320"
     CDS             80562..81917
                     /locus_tag="PK063_02320"
                     /EC_number="2.4.99.12"
                     /EC_number="2.4.99.13"
                     /inference="COORDINATES: protein motif:HMM:NF016311.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-D-manno-octulosonic acid transferase"
                     /protein_id="HMZ95901.1"
                     /translation="MWYLLYNSLLLLVSPVILCVLLAKQRCRRGLPQRLGLLPEQPRE
                     AAPAPTCIWIHAVSLGEVVAVAPLVRELRRRYPEARLVVSTVTETGREAVEQRLEGLA
                     EHRYAPLDFPWVVNQTIDLLRPNLYVFVETELWPNLLRSLRRRNIPSILVNGRLSTRS
                     FERQRLPLIRDFYRTMLNMISCCLMQSERDAQRMVELGADQSRVRCTGNIKFDQPVPQ
                     AAAGGTVVSKQALGLSERERLVVAGSTHPGEEDMIVDAYQSVCEEFPELRLVLAPRHI
                     ERAAQVEQMVRAKGLPVSRRSTGKMESMATSGPRVVVLDTRGELALLYREAEVAFVGG
                     TLVPIGGHNLLEPAVWGKPVLFGPHTDHCAEVATLLLNARGGRVVDGAQGLAQSLREL
                     LGNSDDLKRMGQAAQQVVADNQGALQRSAEIIATFLPPSATSTRSEGATRGALPHPRS
                     S"
     gene            81923..82981
                     /gene="lpxK"
                     /locus_tag="PK063_02325"
     CDS             81923..82981
                     /gene="lpxK"
                     /locus_tag="PK063_02325"
                     /EC_number="2.7.1.130"
                     /inference="COORDINATES: protein motif:HMM:NF014645.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009029 - tetraacyldisaccharide 4'-kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetraacyldisaccharide 4'-kinase"
                     /protein_id="HMZ95902.1"
                     /translation="MRQSWLRWVGYPYEVAARLRLWGYARGWFQTHRLPRPVISIGNL
                     TMGGTGKTPVVMYVVDRLIAQGKRVAILSRGYRRRSKAPQLLVSDGQQVLVGPEEAGD
                     EPYLMARRCPHAVVAVGADRYALGQWVLSRLPVDCFVLDDGFQHVQLHRDVDLLLVDA
                     TDTAGLRAALPVGRLREPLSAAARASAVLITRVDREEAGEQVWRQLVQACPALPSPVC
                     VGFPAEEFRRIGGDEGRPRDAFRGRSAVIFSGIGNAGSFHAVVAELGITVIETLAFPD
                     HVHYTHAMMETIRARAQAGGVDLLVTTEKDADKVAPFLNADDACWAIRLRTQIISGQE
                     RLERLLRLEPESRPASDA"
     gene            82974..>83425
                     /locus_tag="PK063_02330"
     CDS             82974..>83425
                     /locus_tag="PK063_02330"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013257.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 9 protein"
                     /protein_id="HMZ95903.1"
                     /translation="MRKEEIRRIVVRGPNWLGDAVMCEPALSQVRTLFPQAEITLLVK
                     PAIADLLAQHPAVNRTLVYDDRGRHAGLTGKWTLAGVLRRHRFDLAILFQNAFEAALI
                     SFLAGIPRRFGYATDGRSVLLTDPVAVPPRSAQRHQVEYYWDLLKPLGG"
     assembly_gap    83426..83525
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <83526..84284
                     /gene="gmhB"
                     /locus_tag="PK063_02335"
     CDS             <83526..84284
                     /gene="gmhB"
                     /locus_tag="PK063_02335"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: protein motif:HMM:NF006506.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HMZ95904.1"
                     /translation="RQPVSCAPCLLRECPIDHRCMTGVTVEQVHDAAARHLPLAAPPS
                     LIVPTVVKPALSPTALAGVTVFLDRDGTLNVDTGYVKTPEEFTLLPGVGAALARLKGG
                     GAKLVVVTNQSGVGRGYFSSKDLEAIHNKLRLLLAEDGVTLDGLYFCPHHPDDRCNCR
                     KPSRGMVDRALAELQVDLSRAYVVGDSVRDVELAKQVGARAVLVMTGPSGAEALADLT
                     ARDLAPDHVAADLSHAVEWTIAHATRKPVADVAG"
     gene            84309..85352
                     /locus_tag="PK063_02340"
     CDS             84309..85352
                     /locus_tag="PK063_02340"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013257.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 9 protein"
                     /protein_id="HMZ95905.1"
                     /translation="MTEPVRRILLIKPSSLGDIVHAMPTLAALRERFPQAEVTWLVKR
                     QWASFVEVIKGVDHVCAVEQGLRGWLGRVPDLRAARFELVVDLQGLFRSGAMAWLTGC
                     SRRVGFANAREGSPFLYTQRVAVPNGSMHAVDRYLLVAEALGAARQTDPRFDFADRAE
                     DRGAAEALLTAAGIRASAPWIAMNVSARWETKRWPAQHFAEAADLLAEAQHIPVIFMG
                     GPAERPETRAVMARMRTKAVDLTGQTPVGLLPSLLRRAAVFVTNDSGPMHIAAAVGTP
                     VVALFGPTDPVKTGPYGQGHVVLSNPVECRPCFRRECSRAATLECLTGVTPEQVVRAV
                     QRQLGRLDTSGSS"
     gene            85349..86452
                     /locus_tag="PK063_02345"
     CDS             85349..86452
                     /locus_tag="PK063_02345"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HMZ95906.1"
                     /translation="MNILIAESSMAVGGQELAVLLHAERLVARGHHIRLVLEPRSPIM
                     AMAQERGLPVEPFVMRQWRLPLSILAFRQLLTRERPDIVHVNSSRDSWIAALSTRLLN
                     PRPKVIRTRHISAPLNNNATTHLLYRRLFDMVIVTGGERNRQDLIHRDGLSPDRVAAF
                     PIGLDVEQFSPAQPTHDIRAELGIPPRHLLIGMISYLRDYKGHRYLVDAAAKVLKQHP
                     AAAFLIVGEGPEEQNIRAHIERLGLAADVRMLGFRDDLLDVFRSLNLFVIPTVEGDTI
                     PQVLMQALAVGLPVVSTTTGSIPDVIADGESGFLVPPRDPEALADRIVRLLKDANLRA
                     AMGKRGRHTVEQSYSIDRMVDELERVYRKVIAS"
     gene            86449..88590
                     /locus_tag="PK063_02350"
     CDS             86449..88590
                     /locus_tag="PK063_02350"
                     /inference="COORDINATES: protein motif:HMM:NF013080.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HMZ95907.1"
                     /translation="MMLRWADSGASIRKSVLFWWILFVVIQMAERVFLLRDALDQETP
                     TASLLLKTLLVGVRGDFITATFALVLGGVGAGLYSLLRQGVAGFRQSPRRFSLSFRPA
                     FHVGCLLAGLLLFVLLCVDMGYYGFNHQHMDFVFLEYIGDLLAPAATTEGTNVQAMQQ
                     TSAELEAAGKWAWRLTVFLTIQAAGIGLWWWSFSRAVVPALDRWRPGSGFQANALLVV
                     ALVAGGAGFHHSGPYGIRIAPIGSMVYYTLAQNPVLFAAEALRIAVVSRNPIERRANT
                     EAMPYDLAVRTAQQLLGPGETFVDPRYPFVRTTSPSPDGVRLSKPANILLVFLEGLDR
                     RYLGQTYGEVKGTPFLDRLKQDSVYFQNFFSNGVQTSRGLFATLCSTFPRQGAAAMKT
                     RYAHDYLCLPSLLQRQGYSTEMVIGQHRDLNRLQTFVARNGLQQLLDEGDFPANTERA
                     GLGIVDGALFDLCYERIKLRQSQGKPFFLSTLTLSTHHPFAAPMNHPEVQLLQQQVQD
                     KYVAALRYTDLELERTFTRLVREGLLRNTIVVILGDHGRHEPVGGSDIERKVGHFASP
                     LFLWMDESLRTPATYRPRVVDTIASQVDVAPTLLSLNGGLPAMGAFAGHDVSCALVQD
                     CLPGQVAYLTSVYDNLVGLASAEGLLLYSFATETFQEATLRFEPVPDEQTGGRRLSVS
                     RDRELMALYEVANVAMDSNRLWSWREFGSRL"
     gene            88647..89444
                     /locus_tag="PK063_02355"
     CDS             88647..89444
                     /locus_tag="PK063_02355"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012745.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HMZ95908.1"
                     /translation="MDRIPVSAVVIAYNDEPNMRACLESITWADEIIVVDSHSTDGTE
                     RISREFTDKVYQHDFHGFGRLRNEALAHATHDWVFSLDTDERATPELRDEIRRLLDAG
                     PEADAYFVPRKNYFLGRWIKHCGWYPDYRQPQLFRKSKLRYRDELVHESFDLDGRLGY
                     MTAAALQYPFRDIDHYLAKQERYSDLMAKRMVEQGRAFSWHQLVSHPCFTFLKMYVGR
                     KGCLDGVPGLILSGLYAYYTFIKYARFWELQSQGVRQPNRVAPAKQG"
     gene            89475..90236
                     /locus_tag="PK063_02360"
     CDS             89475..90236
                     /locus_tag="PK063_02360"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012745.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HMZ95909.1"
                     /translation="MTIAAVVITKDEEHNIAECLQSLRWVDELIVVDAESRDRTVELA
                     KGYTSKVFVRPWPGYGPQKNFGIDQAGADWILVVDADERVPDALRQEIQALVDSRPPA
                     DIGGYEIPRRNVFYGKWIQGGGLYPDYQLRLFRKTAGRYDDVRLHENLALSGRRERLR
                     EPFIHYSMPTVNHHIRKMMRYTTLGADEKLKRVRHISGWTIATHHLGTILKTLFTRGG
                     YRDGVHGLVVAMFAGLHTFVKYAKAWERLNVRRDA"
     gene            90286..91389
                     /locus_tag="PK063_02365"
     CDS             90286..91389
                     /locus_tag="PK063_02365"
                     /inference="COORDINATES: protein motif:HMM:NF012744.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HMZ95910.1"
                     /translation="MRIGIDASSLVGDKGGVGWHTYHLLKALLQLDEKTDYVGYLRPG
                     SLQAGQLSGWPSRSRMQWMETPRWLMSWRGRWDRLDLYHGPNFKMHTTGRYGGIVTIH
                     DLWLARHPEYSRKLFGQAGSSRRAIATAKRARKVVTVSEFSAREIESLYGIPRDHVRV
                     IYNGVSEDFTPLCDDQIRAEVRTRWSIPSSGFILFVGGADPRKNHVGFLQAVGACRSQ
                     LGGRAIVLVGDAEHPQGSYTATAQSLGLEQEVRCTGRLDREDLRRLYSCADLFVFPSH
                     YEGFGMPVLEAMACGAPTVTSSTSSLPEVAGDAALLVDPNNVEELAHAMVTVLSDTHL
                     RENLRQRGYERARLFTWQRAAVSTSALYRELCT"
     gene            91386..92444
                     /gene="rfaQ"
                     /locus_tag="PK063_02370"
     CDS             91386..92444
                     /gene="rfaQ"
                     /locus_tag="PK063_02370"
                     /inference="COORDINATES: protein motif:HMM:TIGR02195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative lipopolysaccharide heptosyltransferase
                     III"
                     /protein_id="HMZ95911.1"
                     /translation="MIATGLLRPKNILIIKLRHIGDVLLSTPVLRALREAFPAAQLTM
                     LVNRGTEGVLAHNPDVNEVLCLEKGAWADQCKFVYRLRERGFDCVIDLTDGDRSAVIS
                     LATGAPIRIGFNAEHRWRGLLYSRVAKPRPVDQHRVEYDLCALRALGLDPKRGMPSVS
                     VSDSEEQVTDQWLTEQGLIGDQCPPLVLLQPGARYSLKVWPPERFAQLSDRLVEQFRC
                     RILLGGDQREREVAEQVARKSHCAPIVVAGKFSLLQYASLVKRCALFVGNDGGAMHIA
                     ATVGTPVVALFGPTYPERWGPRGGLTQVIYKGLDCRACYHPSCLRGDDSCMRQITVDE
                     VFEAAGRILDLKGARVVT"
     gene            92441..93337
                     /locus_tag="PK063_02375"
     CDS             92441..93337
                     /locus_tag="PK063_02375"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF021616.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family A protein"
                     /protein_id="HMZ95912.1"
                     /translation="MNESVSVVIPVFNGAPFVAKAVASVRAQAHGDVEILVVDDGSTD
                     GTQEVLKRLEESDGIRWFQRSHGGPARSRNFGIEAARGQYIALLDCDDVWLPGKLAAQ
                     LAIMRTRPEVGLVHTDFDVRFEDGTLEERVIARSSREPMVQAFAGGHVALPSTLLIRK
                     SVLDQVGRLDPELYGSEDSDLTIRLFRVTSFECIDQVLVTKLQRGHGYRDMAFDEQTH
                     RERVLASRDRFLMRLEGFAPLTTAQRAALDREWANYYLLKGAAAERAGRPAEARSQYR
                     KAIGKAPGRIRCYTRWLRTWTS"
     gene            93369..94406
                     /locus_tag="PK063_02380"
     CDS             93369..94406
                     /locus_tag="PK063_02380"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF024880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HMZ95913.1"
                     /translation="METIDCEVCGGTSTTTMFSQYDLTHRVTDDVFTVVRCLDCRQLF
                     LNPRPTRQEIGRYYPDTYYPDAAPRQAGDLRRAAKRWSATIRRWIAQDFYGYPAQEQG
                     RAWQRVRRMFLWPEFLWRCWRGRGLLPWVGQGRVLDVGCGAGGNLASLQEQGWEVSGV
                     DASAVAVTQAKACFGDRVRLGDLEAIAYPDRSFDTVLFSHVLEHLHGPLPLLKEVWRI
                     LDQDGRIVILCPNAGSLEAKIFGRWWFPWELPRHLFHYEKATLRRILEAAGFRIESMR
                     TGLGSLYFMASLDRVCEQRFGRAIPCRRLLEKSLIRPFCFCVGHLGYGTELKVYARKD
                     ASLNQATQSTI"
     gene            complement(94387..95262)
                     /locus_tag="PK063_02385"
     CDS             complement(94387..95262)
                     /locus_tag="PK063_02385"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF021616.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family A protein"
                     /protein_id="HMZ95914.1"
                     /translation="MAHVSVVIPAYNGTSRYLNEAIRSVQAQSFADYEIIVVDDASTD
                     RTDALVQAIPQVRYVRHSKNAGQAAARNTGAQLAQAPYLAFLDQDDLWEPTFLERTLA
                     ILEPATGAVLVHCDGYQVNERNDILEYDAAMKHQRSITQLLRGGHDAATSGSLFRKSW
                     FDSVGGYDAALSIWEDIDLAIRLYGPERFIHLPEPMYRHRLYGHNASRDIPSLRALDG
                     RRRFLEKHAATCRPGTPEGEALSNDWAIYYADLGKHHLRAHARQEARQAFRFALRHQP
                     LNFKTWSRLLRSYFV"
     gene            95442..96524
                     /locus_tag="PK063_02390"
     CDS             95442..96524
                     /locus_tag="PK063_02390"
                     /inference="COORDINATES: protein motif:HMM:NF012744.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HMZ95915.1"
                     /translation="MKIVIAAWHLKNFNVGIGRYARELIEALGSVDQTNHYDILLPQP
                     EHPFTARPNMRYRVVRFPLFRRRFWEQVAPLMVGPYDVLHFPYDSCVAWKRGKFVTTI
                     HDVKPLLFPELRPRTNLNSRIEDWLVGDRWQTIDQVITVSEHSRRDLLAHVPLRPDQV
                     SVTPLGLDAGRFRPAEHRHEGRPYVFCVAGSDPTKNVGVLVEAFATLPADLRNRFDLI
                     LAGDVCKREDIRAAIARRGLGAQVKLVGLLSDADLVTYYQQATVFVFPSLYEGFGLPV
                     LEAMGCGCPVICSNASSLPEVAGEAAVLVDPRRTDQLTQELARVLESIELQLSLRERA
                     LARSKEFVWERTAKQTVAVYERAVGR"
     gene            96671..97405
                     /locus_tag="PK063_02395"
     CDS             96671..97405
                     /locus_tag="PK063_02395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HMZ95916.1"
                     /translation="MKGVVLAGGLGSRLLPLTKVTNKHLLPVYNKPMIYYPIQTLVNA
                     GITEIMLVTGGNSAGDFLKLLGNGRDFGLKHLSYTYQQGEGGIADALRLAEHFADDGP
                     ICVVLGDNLIQGNIAKAAEAFRTQKKGAKILLKEVKDPQRFGVPHLDGNQVLSIEEKP
                     AHPKSSYAVTGIYFYDARVFEITRTLKPSGRGELEITDVNNAYIASGELTWNVLDGWW
                     TDAGTIESLLAANQLVAQTGANRMEF"
     gene            97405..>98201
                     /locus_tag="PK063_02400"
     CDS             97405..>98201
                     /locus_tag="PK063_02400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HMZ95917.1"
                     /translation="MRILVTGGAGFIGSHLVRRLVQSGRHSVVNLDALKYSGNLENLT
                     DLVDHPQYRFIHADIGDQKAVHAALQEHRIEGIINCAAETHVDRSILDPGAFARTDVV
                     GTGILLEEARQAGVQRFLQVSTDEVYGSVEQGSSTEGDRLEPRSPYSASKAGGDLLVL
                     SYWTTYRFPVVVTRGSNTYGPNQYPEKFIPLFATNAIDGEPLPLYGDGKQCRDWLSVY
                     DHAAGIQHVFEDGQPGTVYNVGGGNERENIMVAEQIVAALGKSRSLIR"
BASE COUNT        19722 a        26669 c        30478 g        20932 t
ORIGIN      
        1 tcgtgatggc atacgccttg ctttaatgtc tgccatcaca gtgagcgtga tcggaacagc
       61 gaaaggaatg agccatggta aagatcatca agaaagttgg agatcgggag ttggcctggg
      121 tgatgttggc tgttgcagcc gttgcgctgt ggagcacctg ggggcttgcc agctaagttt
      181 gctgaaaggg tatccgccta cccgtgtgag cgtatctgat ctcagtgaga tgcgcgtgaa
      241 ggtggttccg gtttccagtt gcctgcaagg tcattctctc tctgcacgat cgatcagttc
      301 ttttaacacc accgcctgat tgtgtttcac gtctgaagac ccgaacagca gcgtcagtgt
      361 ctgcgatcga gccagcgcca cgagttcttc gatcgccctg cgttgtgccg gttgtgccag
      421 ctcagcgaga taccgcgagc gaaactcctt ccacttccgt ggatcatgac caaaccatgt
      481 gcgaagcgcg gtgctgggcg ccaattcctt ttgccagtca ttgagccgcg cccgctcctt
      541 cgtgcaaccc ctcggccata tccggtcgac caaaatgcga attccgtcct gtggatccgg
      601 ttcgctgtag atccttttga tatgaaccac ggcgatttta cctcaggtcc aagccgtctc
      661 tagtcctgat gtgagcagca atgccaatgc caaccggaat caccagcgaa ccctcatatt
      721 ccattgtaag tgattcaaaa aaacagttcg actcgagcga ttccgcacga gatgtaccgt
      781 gcgaaatgcg ttcccagttg gcccaccgtg ccgatggcca ttcggtacca tcgcgtagcg
      841 cagcaattac ctgagcttcg tctccgcttt tgacaggacc atatattgca aagccacttc
      901 cttggaccgg aattcaacag cgcatcctcg cagatggtgc gcaagggagg ggcgatgatc
      961 cgtcaatctg gttttccgag tgacgatgtg atcgacaacc aaattctcgt gttgttacac
     1021 cgccaccggc gactgacctt tctcaccttg gcagatgcgc tgccgttgta tacctggcaa
     1081 tccctgtttg cggcgttgaa ccggttgagg acacaagagc aggtcgaact attgcccctc
     1141 gctgcggatt acgaagtgat ttggcggagt ggtcgagaga ccgaacccct gttgtcgaag
     1201 ggggggcatc tgcaggtgcg atgatgcgcg tgtcgtgtcc cgctgttgtc cgatgtctgg
     1261 tgctggtggc agcctgccag atgcctgctt gtgggaacac cgcctcggtg ttcgatttgg
     1321 agacaaacga tccgagacag gatcaggaaa aaatcgctga attctatgca cacgaagcca
     1381 cgaggctgcg gcagatggcg caggattatg accatcgtgt ggccgtgtac gaacggttgt
     1441 ttggccctca ctcggattgg gtcgaaggca cgcgactctt gtcacaatcg tatgaggctg
     1501 cggcacagga acaagaacgg atagccgctc gccatcagcg cctccatgac cggcgttccc
     1561 atgctgctga ccaggaatcc cgctgaatga catgaatgca ggaaggggga gaccatgtgg
     1621 cgatatacga cgatcggact gatcattgca gggctgtgcg ggttgtctgg ttgtggaaac
     1681 acggtcagcc ctggacagcg cggtctccgc tggtacccct tgaccgaggg actgaccacc
     1741 gagaccttga agtccgggtt ctattggaga gcaccctgga acgacgtgta cgtctatgac
     1801 gtgcgtttgc agagttacac ggaactcgtg gacgcgttga gctccgacga tctgttggtc
     1861 aagttgaagg cagccatcat catgcgtccg attgccgaag aagtgtattt cctcgcgcag
     1921 gagatcggcc cggattttta tccgagggtc gttcgaccgg aactgctggc cgcggtgcgt
     1981 agcgtcgtgt cgaactatcc gatggtcgcg gtcccggaaa tgagcgcgga aatcgccagt
     2041 aaagtgcagg cagttgtggt ggagaaactc aagggccgtc acctggaagt gcacagcgtg
     2101 gcgctcgccg atattgagtt agccaagatc gtgctggagg ccgtagagcg caagcaagcg
     2161 aaggagcagg aaaaagaaca aaaggaattc gaactcgtca tcgcggagaa ggaagcggag
     2221 atcgccaggc ggcgtgcgcg cggcgagggt gatgccattc gaatccgatc ggagggcgag
     2281 gcggaagggc tgaagattcg agcgcttggc caggcgaatg cacagcaaac gatcacgaaa
     2341 accctgaccc ctgaatattt gcaatacaaa ctctatgaca gccccaacgc gaaaatggtg
     2401 ctgctgccgg atcagttgcg cgtgccgatt ctgatcaatc ccgatcagga tcgcgggacg
     2461 aggtcgactc ctgagagtct catgcgcaca gagcaggagt tgatggggcg gggtcgctag
     2521 atcgcttcgg acggctattg atcgaaggag gccacggatg gcatgcagcc gatgtcaggg
     2581 cttgatggtg gacgagacgc tgttcaatcc aagcgagggc gtgagccata cctgggtgcc
     2641 ggtcgtccgc tgtctcaatt gcggcaatct ggaagatgcg ttgatccggt tggctcgtgg
     2701 catctccgga cgtctggggc gccgcaccag gccgggtccg caacgaaggg gcgtctggag
     2761 tgaggagatc cgcgggcggc aaaaggaatg aatcggctgt ccgtcagtgc gacaggtgga
     2821 gggatgtgaa ctgttgcgat gcaccagagg aaggagacgc catggagggc tatgggaagc
     2881 gcgtgttgat cgcggatgat gaagaaagtg tacgacggct ggttgcgatc gtgctggagc
     2941 aagcagggta tatcgtccat gcggccgtcg atggcgtcga ggggttgggc gagatgaaga
     3001 agcggcgctt cgatgccgtc atttctgatt ttcacatgcc tcgcctggac ggggagcaat
     3061 ttctcctgct ctgtcgcctc atgtggcctg acattccggt ggtattgctc tccgcggagt
     3121 tgctggaact ccccgccgcc ctcaaacagc agggcgcgtg catcctggtt tcgaaaccct
     3181 tttctccgca aatgttattg caagccttgc atgagtcgct ctcattgccc gaaagcgagc
     3241 aggcctcgga ccggatcact tccaaggcgt cgtaatctca atccctttca ttcgatgatg
     3301 cgtagatgtc ccggcgcgct gacaacctgg cgtgcctggt gcatccctag gcggtcatcc
     3361 ttaccaaatg agtcactctg tcattccggc atccagatgg cgcgatagcg cacgggccga
     3421 gcggtgcgaa atctggatac ggtatccgtc ctctgtgatg gaccctccct ccatagagat
     3481 ctgagataga gcaatcacgg tttgtttgac gctgcctggc ctttcacctg caggatcata
     3541 tcttgcttcg ctcagtggtc ccgtgacgcg atgactgacg gtacagagga ggctcatcat
     3601 gaagactctg ctatcacacg catgtgtcat tcttgcatgg agtacactcg ccggatgtgt
     3661 ggccacgtcg gttcgggaac ccttccccgc cttgtccgat gcttctgtga tggggatgac
     3721 gcgagggcca tcggaaagcc gtctccagtg gcatgaagac gcgcaggagc tgcggacatt
     3781 cgccgatcgc catgaggtcg aagctgaagt attgctccag caccccgtgc cgacggatgc
     3841 gcggttgatc cagcagcggc gggcccttgc ccgacagctg cgagctgctg cagatcagat
     3901 cgacaaacgg gcggatgaga tgccatagcg gtgcccgcaa tctaaggtgt ctcgtacgat
     3961 ggtctcagcc agggactggc ctgcgtaatc ctcatgcacg acgaatagtc gagggaggcg
     4021 aaacaatgaa tgatggaacc gaccggaatg acggctacga tgtagactcc gcggtgtggg
     4081 cctatttgca gcgctgccgg atatgttcga tggaggaatt gttccgtcat gtgccgacgt
     4141 tcacagcgaa ccaactgttt ctcaccgtgg atcggctcag ccgggaaggc aaggtggtgc
     4201 tgcggtacag gaaccgtgcg gaatatgtta tggtgcgaac agggattgcc gacgagtggc
     4261 ctcacgaaat gtcgggcgca ccgtttggcg acaggacatg agggaacaag gtatgaaaaa
     4321 gaagaccgcc ccgaaaaaag ccgccacacg cacgacaaag caggttgcaa aaccagctgt
     4381 gtccgagaag cagcctggac ctgtgcagga tattcaagtg cggattgcgg ccagggcgca
     4441 cgagctgtac gaacaacggg gatgcctgga cggctatcat ctccgcgact ggttggaagc
     4501 ggaacgagag attctggggc atccggtcga gatggacaaa tcttccgaac gcatttagtt
     4561 ctccttgccg gctggttgtc tgcagccctt ccaatgtgat cccggacgcg tctttgttag
     4621 acccggcgct cctgcctgtc gctcatctca tggtctcttc cagctgatcg accattcctg
     4681 aaatcgcatc gaagccggac tgccagaacg cgtgggagtt catgtccaca cccacctgag
     4741 ccaggatcgc ctgcggtgct ttcgatcctc cggccgccag gaggtccagg tacttgggga
     4801 cgaatgcggc gccttgttcc tggtacatgc gatacagcgc caacacgagc agattcccga
     4861 agctgtaggc ataacagtag aaggggctgg catacagatg cggaatggtg agccattccc
     4921 attggaactc ctgcggtacg cgcagcgatt tcccgaactg ctgtttgagc agggtcatat
     4981 aggtgccggc cagatcattc gttgtggcgc cctgggcgac catgtcgtgg gctgtccgtt
     5041 cgaaggcgac aaagtacgcc tgacgcatga cggtggcgta gatgtcgtcc aactgattca
     5101 cgagcaggct ctgtttcacc gacttgctcg actccgaggc catcaaggca tctgaaagaa
     5161 tgcgctcgcc gaacacagag gccgtctccg caagcggcag cgtcgagtgg aaagtgaaca
     5221 cgttgtgctg ctccgccatc atggcgtgaa cggcatggcc taattcatgg gccatcgtcg
     5281 caatgtcgcg cgcctctcca gtgaaattca gcatgacata gggcgttaca ttcggcgtga
     5341 cgctgtagca gtaggcgccg cccatttttc ccgccttcat ccgagcatcg atgtgccgat
     5401 cggcaaagac gcgttgtgcg agttcagcca aacgcggcga gaatccgtaa taggcgtcta
     5461 gcaccatgcg gaccgcgtcc gggtaccggt agctcttttg ctcggcgcga tgcggtgcat
     5521 agatatggta gcggttcatc gtgctgatct tgcagagctt ggctttgagc ttgaagtagc
     5581 gctggaagat cggggcgttc ttcatacaga tggctaggag cgcctccacc gcggagtcgg
     5641 gaatgtcgtt gctgaggttc cgggaggcca gcggtgtctt gaaatggcgg agttgaagat
     5701 tttcggcctt ccaatcattg atcaacgtct tatagatctc tccgagcaga tcctgctggg
     5761 attcgtacac gcgatacatt tcccggtagg ccgcttcccg cattgcagct ttcgggcttc
     5821 tcagataggc cgtcaacgcc tcgcggttca tggtcttgtt cttcccgccg atgcgcagcg
     5881 tgaaggtgaa gccgttggtg accacatcgt agagctgatg cacggcgctt tgtccggtga
     5941 tgttcttgat gttgatgatt ttctcttccg gctccgagag cgtatgcggt ttgaagcggc
     6001 ggatggtttc caggtgatac cggaagtccc cgctattcgc catcaagcgc tccgcatttt
     6061 tctcatccac gctttgccac cacagatcga aaaacaacag gcgattctgg agactggtga
     6121 ggtgctcttc cactttggtc ttgaacgacc gggcctgcag ctgcttggta tcttcggaaa
     6181 accagagata ggagtaggct cccagccggc cggaatcgcg cgcgatctgt tccgacaagg
     6241 tcaggagatt caagaagctt tgctcggaca tggttgcgga gaggtccggg cgtgccgctt
     6301 caaagcgcgt caccttggct gtcaggtctt tcagatatcg atcgaattgt ttcacgggat
     6361 cggcgacaag gtcggccagg tcccaccggt cggcaaattc gcgggatgtc gtggaacgtc
     6421 gggatgatac tgttgcagat gcagtcttgc gggaaacggc cataatcggg gctcctacaa
     6481 atgagtgata gccggaatca taccatcctc gccggctcag ggcgtgtaga ttctttgagg
     6541 gcaggctgtt cgggctgatg caccgttgac aggtcccgct tgaatgttac aatccggcca
     6601 tggtggggag cggggacatg accgaacaag agatcaatcg ggccattcaa tatgtgacag
     6661 cggcgacgtc ctacggccgg gacacggtgg cggagattct ccggaccggc ctgtccgagt
     6721 tgtctcaact ctcgacacaa tcgacccggc ggttcgaacg ggaagatttg atgggctatc
     6781 tctgtcagtg gaccatgaaa cgtaccggcc atccggagcc gctggtacgc gaagtgctgg
     6841 atggggccgg tcgttggttg gatgaggtgg cgaccacctt agccgagcag cgtgaagccg
     6901 aggccaatgc cggcgatgat gacgaaaccg gcgcggcatc ggcctgaggc atccgtccgc
     6961 cgtcaactgc gcagtcttcc tcgcgacgca cgatactgac gaatcaccga gcctggaatc
     7021 aggcggcggg gagcgagctc ttcaggagtt caaggttttt tgtcaccatc gcgtctccat
     7081 tcttggtcga cacgtcgatc ccctggtctg acacctggcg gcattcctcc acacggttca
     7141 gtttcaatag cgattgcgcc aaggcatagt acgcagccga gtaggtcggt ttcaccgtga
     7201 tgcactgcct caaggccttc gcggcttcct cgaagttggc atcttccata taggcttttc
     7261 ccagcccgaa ccaggcgaca tcatcgtccg gctccatggc taacactcgt ttcagcggtt
     7321 caattcgtgg attcggcatc gagtcctccc tttggaggac gataacagcg ttctcggcgc
     7381 gttgtctacg cagtttgacg cgtgttaagg tcaaaagacc tcttgtcgtc ggcaatgtcg
     7441 ctggcggttt ccccggcgcg agtactcaat gggaagaact ggtctcgttt acgatcctcg
     7501 ctatctcgcc cacgatatgg gcgccggaca tccggagtcg cccaaccggc ttcgtgcaat
     7561 catgcagcga ttagagcaaa gcgggttggc tgctgaactc acccgtctag caccgagaac
     7621 agccgaggat gagtggatca cgttggtcca tcgccccgag tatgtcgggc atctcaaccg
     7681 cgaagcgccg actagtggcc gggtatctct ggatgccgat acctccatgt cccccggatc
     7741 gctcctcgcc gcctatctgg ccgcgggcgg ggccttgtcc ggcgtggatg ccattatggc
     7801 cgaccaggtc cagcatgtct tttgcgcggt ccgtcccccg ggccaccatg cggaggcagg
     7861 gcgggccatg gggttttgtc tcttcaacaa tgtcgccatc gcggcgcgct acgcgcagaa
     7921 acgttatggg gtgcagcggg tcctgatcgt cgattgggat gtccatcatg gcaatggcac
     7981 gcagcatagt tttgaggcag acccctcggt gttgttcttc agcactcatc aatacccgca
     8041 ctacccgggc accggtcgcg cgacggagtg cggcaccggc gcgggggaag gcttcaccat
     8101 caatgtgccg atggaagcgg gtgagggcga cgacgactat cgggcggtgt ttcagaaagt
     8161 gctggttcct gccgccgatg ccttcaagcc tgagttggtt atcatctctg ccggctttga
     8221 tgcgcatcgg gatgatcccc tggccagcat gggcctgacg gaagaagggt acgcagactt
     8281 gacctcgatt gtggccggca tcgcgactcg gcactgccgg gggagactgc tttcctcgct
     8341 ggaagggggc tataacctga cggccttggc ggcttcggtc gagcggcaca tccgggcact
     8401 ggtggcgtca tgaaatggtg gctgaagctg ttgctcggcc tcgcggtcat ctcggggctg
     8461 gtgtacctct attacacgga ggtgaagccg gtcgtcattt tcgggctccg gtccgagtat
     8521 gcgcatgcga ttcccttcca gaagattccc gaaggcttga cgagcctcaa ggccgaatcc
     8581 tgcggtcaat gtcaccggga gatttatgag gagtggaaga cgagcattca tgcgcacgcc
     8641 tatgaagatc ccttttttca ggcgtactgg aagaaagata aacaggtctg ggtctgtttg
     8701 aattgccata ccccgctgga gaaccaacag ccgaccttgg tgaaagatat cccgcggggg
     8761 cgcgtggaaa aggcgaccca ggaaccgaat ccccatttcg atgccgcgct gcaaaaagag
     8821 tccatcacct gcgcggcctg ccatgtacgc gatggggtca tcctcggccc cttcgacgat
     8881 tcggctgcgc cgcacccgac caaatttgac ccgacgttcc gcaccgcgca gttttgttcg
     8941 cgttgccaca atgtggtctc aggtcctgcg cagttctaca atgtggggcc ctgcggcacg
     9001 tatgcggagt atgaaggaaa atatttcatg caggagcggg gctttatctg ccaaagctgc
     9061 cacatgccgg aggtggatcg ccccgtggcc gagaacggac ccatcaggcg gggccgccgg
     9121 catctctggc gcggcggtca tgatcccgac atggtgaagc gggcggccgc gattcaagtg
     9181 aaggtcgatc ctcccaagcc caagccgggc gaccaggtca cgatagccct gaccctcacg
     9241 aatgccggag cgggacataa gcttcccacc ggcgatccgg accggcactt caccgtcgaa
     9301 tttacggtga aggacagcaa tcagcagatt ctggccgaaa agagccatac catgggtcgc
     9361 tggattatgt ggcagccggc cattgtggag ttgtacgaca accgcttgct gccgctggcg
     9421 agccgggaat atcaattcgc ctaccggatg ccggaagcat cgaagggggt gaccttgaag
     9481 gctcgcgttc ggtaccacat tctgaccgac ggtcagcatg agatgttgaa gaagaaatac
     9541 ggtctcatgg cggacgatcc ctacgccttc acggtgtatg aacgagaggt gccgctgaac
     9601 gaacagctcg cggccgcgtt cgctgatccc ttgcctgagc cgccaccgat ggcctgcgcg
     9661 aatccatcag ctccacaagg ctaaggcgtc atcgaacggg atcggacaac ctccaccaca
     9721 tccgttcgcg accattaaac gcactcgata tcctgcaagg gctgaccgtt gatcagcctc
     9781 cgctcatcat tgtaaaggcc aaagcactgg cacgtgcatt ttccttgctc ggggaggcca
     9841 gattaattgg acgaaacaaa ccctttgaga atacgcgcga tgcgcggcgc atagggtatt
     9901 ttctgtcaaa tcccgatggc gcaaagctcg ataagcgtat caatctgggc gagcaggagg
     9961 caggtaggag ggatcttgcg ggaacggtga accgcaggag agctgtttct ttccgtgcgt
    10021 tccggctctg ttttatctgc gtttgcctgg tagtgcggcg aagacggtac atgcttgcgg
    10081 aactgctcat cggacatact gattcgaaag tcgcacagcc gacagacata cgaaccagtc
    10141 aggtacacgt cgcccacgca ctcgagttgg tactcatggt cacattctgg cgtcatcagg
    10201 tttttgtagc atatcgatca tgctaagaca cctgggtgga taccttggaa ggaaatgcct
    10261 atgcaccaca tcagtgtagg aaggctcaac gaccgacctg tgagttttcg tatcgacgcc
    10321 aatgaaatcc cttccgcgtt tcacaatagt cctgttgtgt tcattggtga gggttcggta
    10381 agctgttggc cgggttaatc actcaccgag gatacgcgat gcaacatcca ttactcatcg
    10441 attgcgagac acttcagaca cggttagggc agccaggcct ggtgatcctc gatgtgcggg
    10501 gccgatccac gtacgagttc ggcgggcaca ttcccggcgc cgtgcattcc acctggcacg
    10561 aatacagtga tcccgaggcg atcgccaaag gcctcttgga tccggatgtg aaacggatcg
    10621 agaagcgggt gcaagcactc ggaattaatc gggacaatga ggtcgtcatc tattccaacc
    10681 ccttcgataa ctggggtgat gaaggtcgca tgttttggat gttggaatac ctcggccaca
    10741 aaaacatcaa agtcctggat ggcggttggg tcaagtggat tcacgagcgc cggccgttcg
    10801 agcatggcgc ggtccgtccc acgccaggca acttcaccgt ctcgccggtg gcctccgcga
    10861 tcatcatgaa ggatgaattg aagggtatcg tacgcaagcc ccatccgacc accacgattg
    10921 tggacgcgcg gagtctggaa gagtttctcg ggaaggaagt gtccggcatt ccgagacccg
    10981 gccatatccc cggcgcggtg catgtggcat ggagcggatt cctcaatgcg gatgccacgg
    11041 tgaaggatct cgacgccatt catgcgcagt tggaactcaa ggggttgaac ccggcccatg
    11101 aaacggtgtg ttactgcacg ggcggggtcc ggtcgggatg gctctatttt gtgctgcgcc
    11161 tcgcgggctt tgagcggctg cgtaattatc cgggctcctg gtgggagtgg agccgggatt
    11221 tcgcctgccc ggtggagaag gatctgcttg ccttgcaaaa actgctcggc ttgtcggagt
    11281 cgcaggtgcc gaccggcatg cgtccgtctt gacaggatag gggcccgtct ttatgctgaa
    11341 ttagaatgta ttcggattga tgcagtgcac atacttacag aggaggcgtt tcatgcagac
    11401 tgctatgtgg cggggagtcg tggtggccgg agtcatgatg gcgctcgtcg gagcgccgat
    11461 ggtatccagc gtggctttcg cggcggggaa taagcatcaa gcggaagccg tggagcatgc
    11521 caaggaagcg gtggcgcatg ggaagcaggg ccatgcggat gcgctggtga aacatgctga
    11581 ggcggcgctc aagcatgccg aaggcgccat ggcggagacc aagaatcctc atgtgggtga
    11641 agccatcaag ggcttgaagg acgggatcga acacggtaag gcaggccatg cggatgtggc
    11701 gaccaaagcg gtcgaaaacg cgcttcccca tctgtccgaa ggtatgtaag cggttcttgc
    11761 gcagcgacga cgcgtacgat aaaacgggca ggggcatccc tgcccgtttt tctttgtgta
    11821 gaaaggcagc atgatgcggg ttggatatct gcaaggtgat ccggtgttcg gcgaggtcgc
    11881 gcacaacctc gatactgtga cagctcagct cgagcacgca gaggctgatc tgctggtgct
    11941 gccggaattg tttgcgaccg gctatcagtt cacgtcacag gaagaagtgt ctcggcttgc
    12001 ggaagcggtg ccggatgggc cgacaacgca acgactcctg gagatcgccg cgcgccgcaa
    12061 gaccaccatc gtcgccggat tggcagaacg ggcggggacg aaatatttta attccgccgt
    12121 cgtggtgggg ccaaaggggt tcatcggctg ttatcgcaag acgcatctgt ttttcgagga
    12181 aacgctgttt ttcaatcccg gcgatagtgg ctttcaggtc tgggatatcg gtgcagccaa
    12241 aatcggtgtg atgatctgct tcgactggta ctatccggag tcggctcgca ccctggcact
    12301 gctgggtgcc gagatcattg cccatccctc caacctggtt ctgccgaact gtccggattc
    12361 catggtgaca cggtgtctgg aaaaccgggt gttcagcgtc acggccaatc ggatcggcag
    12421 cgaagcacgc ggcggaaaag accggctgac gtttatcggt ctgagcgaaa tcgtcagccc
    12481 ccgcggtcaa atcctgcacc gtgcgccccg cgatcgtgaa gagctgacca tcatcgagat
    12541 cgatcctgcg gaagcgaggc gaaaggcgct caatagctat aatgatctcc tgcgggaccg
    12601 ccgcccggcc atgtatgggg tctgagcgaa ggtcgcttga attttctgtc tcgacttgcg
    12661 ccccttcatg cctcacggta ggatgaacca tgacaactcc actcactaaa ggcgtgctgc
    12721 tcgtggcgac gccggcattg aatgatccca atttcaggca ggcggtcgtg ctgctctgtg
    12781 aacacgggcc tgaaggagcg ctcggcgtga tcgtcaatcg tccgacggcc atgtccatct
    12841 ctgaagcgtt gccacaggtt cccatcctgg aaggccaacc acacgtgctc tactcgggcg
    12901 gccctgtgca aaccaatcaa gtgatgatgc tctatcgcat cagcgacacg ccggagaatt
    12961 cccatcaggt attcgatggc gtctgcctcg gcggcgacct ggaaatcatg gaacggattc
    13021 tcatggagca gcccggaaag gaatcattcc gggcctactt aggatactcc ggctggggac
    13081 ctgggcagtt ggagtcggaa atgcagaccg gttcgtggat tacgctgccg gctgatcctt
    13141 cgattgtgtt tgagaaggaa gcggcgcgca tttggtcgga tatcgtgttg tcgcttgatg
    13201 agacctctcg ccactacgcg gatatgccct tcgatccctc ctccaattag ccgcgccgag
    13261 cggcgttcat cacgactgcc ggcgttcctg ataccacctc gctgactgtt accctctccc
    13321 actcattgca ggcatgcctc gcctctcagg ttgcgcgcac agcggaactt tccagtacct
    13381 tcgccagaaa ccgtcccgta tgcgactgcg ccaccttggc gacctgttcc ggtcgtcctt
    13441 cggnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnaaccgtc ccgtatgcga
    13561 ctgcgccacc ttggcgacct gttccggtcg tccttcggcg acaatctggc ctccggcctc
    13621 gccgccttcc ggaccgagat cgatgatcca gtcggccgtt ttgatgacat cgagattgtg
    13681 ctcaacgacg atgagggtat tgccggcatc cacaagtttg tggaggaccg ccagcaactt
    13741 cttgatgtcg tcgaggtgca ggccggtcgt cggttcatcc agaatataga gctggttgtg
    13801 tgccgacgga tctttgagtt ccgcggcgat ctttaaccgc tgggcctctc caccggacag
    13861 agtgttggcc gcctggccga gccgcagata ccctaatccg atcgatgaga gcagataaag
    13921 cttttctgtc agcttcggcg acccggaaaa aaacgcctgc gcttcagtca ccgtcagatt
    13981 taacacgtcg tgaatggttt tcccgcgata cttgatagcg agaatctccg gtttgaatcg
    14041 ccggccattg cactgttcgc acgttgcata gatgtcttcg aagaaataca tctccagctt
    14101 ttcatacccg tttccttcgc aacgttcgca ccggccgccg gccgcattaa acgagaaatg
    14161 tcccggcgtg aggccttgtc gcagcgcgtc ccgttcggag gcaaagagct ggcgaatctc
    14221 gtcgaaggcc ttgaggtagg taatcgggtt cgagcgtgga gtacgaccga tcggttgctg
    14281 gtcgatgagg cggacgcctt tgagatattc gagtcccttg atggcttgaa acctccccat
    14341 cgggagtgat tcgatccgaa aggcccgcgc ggcggcccgg tagaccgtgt cctcgatgag
    14401 tgtgcttttt cccgagccgg acacgccggt gatgcagacc agcatatgca ggggaatgcg
    14461 tactagtaga tttttgagat tgtgttcggc ggctccggca atgctcagca ccttgccgtt
    14521 cccggagcgg cgggttttcg gaagcgggat tcgttcctca cctcgcaggt aacgggcagt
    14581 cagggatttc gggtcgcgga tgaatggtgc acgcggcgcc gcgcagacca cttggccgcc
    14641 ttgttctccc gaagccgggc ccatttcaac gatatggtcg gcagcctgaa tcatcagcgg
    14701 gtcgtgctcg acgacaacga cggtgttccc ttcagtcgcc aggtcgcgga ggatgccggc
    14761 cagggtgtct gtgtctcgcg catgcagtcc gatggtcggt tcgtccagta cgtatagggt
    14821 tcccaccaac cgggagccca gctggttggc cagggctatc cgttgggctt cccctccgga
    14881 cagcgttttt gtttgtcggg agagcgtaag gtagttcaac cccactcgca gcagaaaatt
    14941 cagcttggcc tgcaattgcc ggaggatatc cttggcgatt tccgcatcga atgccggtaa
    15001 tgccaaccgc tgaaaccatt ccgtggcagc ctgaatggtg aaatcgttca attgaatgaa
    15061 atcgtgcccg gccaatttga cgaagcgcgc ggccggcttc agccggctgc cctgacagat
    15121 cgggcaggtt gccgggctgc ggtagcgact gagcaggact cgcacgtgca gcttgtagcg
    15181 cttcgtttcc agatagtcga agtattgccg gacgccttcc acctggtcgc tgccttccca
    15241 aatcagctgc tgcacctcgc tcggcagttc ctgaaacgga gccgtcaaat cgacctccag
    15301 tttcttcatg gcgagcaaaa gctgtttctg ccaccagtcc gatcccggtt tgctccaggg
    15361 ttcgatcacg ccgccggcga gcgacttact gcgatcggga atgaccaggt cccggtcgta
    15421 gcgcaggata ttgccgaagc ctttgcactc agggcaggcg cctaatggat ggttgaatga
    15481 aaagagcagg gggcgcaacg gctcgaaggt ccggccgcaa ccctgacacc gaaagtgggt
    15541 actataggtc cggagcccat ggccgatgac atccacctgg cagaccccgt cagcctcctg
    15601 aaaggcgact tcgatggctt cgatcaagcg atggcgattg tcaggtctca gtacgaggcg
    15661 atcgagcacg acctgaaggc cggactcgcg gtgttccggc agtgtgannn nnnnnnnnnn
    15721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15781 nnnnnnnnnn nnnnnnnnnn nnnnnnnacg aggcgatcga gcacgacctg aaggccggac
    15841 tcgcggtgtt ccggcagtgt gatgttatcg tggaggtcca ggatctcgtc gccgcagcga
    15901 agcctggtga accctcgttt ggtcaatgaa tcgagcagcg accggtcgtg gcctggtccc
    15961 agatcgttga cggggaataa aatcatcgcc cgcgcatcgg gaaattgcgc cagcagttcc
    16021 tcggcaagcg aaccggggtg gtacccgcga gcttcctgat gacagtccgg gcaaaccggt
    16081 ttgccgattt tggcgaagag caagcgcagc agatcggcaa cttcggtcgc cgtgccgacg
    16141 gtcgagcgcg ccgtgcgaat cggattcttt tgttcgatgg caatggcggg gcgaatgttg
    16201 gtgatgcggt cgacgtcggg gcgattcact ttgtcgagaa acatgcgcgc ataggtcgag
    16261 agggattcga catagcgcca ctgtccttcc gcaaacaacg tatcgaacgc cagggaggat
    16321 ttgccggacc ctgacaggcc ggtaatcgcc gtaaccttgt tgtgagggat gcgcaatgaa
    16381 atgtttttga gattgttctg acgtgcccct tcgatgatca gttcgtcggt tgatcgagtc
    16441 gggggtgtac gggatgccac ggcgaagcgc tccttctcat ggatgaccga ccatcgtagc
    16501 aagcgctgcc gtcgtctgca atgtcatcga cctgccagcg atgagactcg tgcgatcggc
    16561 ctggatggac tcgtataatg gcgccatcat atggacgact gagaggatgg tatggtggat
    16621 cgttctgctt atcttgcgcg catcgcatac gaagggccgg tggatccatc catcgagact
    16681 ctccgtaggt tgcatcgtgc tcacgtgctg accgtgccgt tcgaaaatct cgatattcac
    16741 cttgggcggc cgatctcgct ggagccgttg gatctctttc ggaaaatcgt tactggtaaa
    16801 cggggcggct actgcttcga actcaatggc ctgtttgcgc tgctattgga agaccttgga
    16861 tttgcggtga ccaggctggc tgcccgggtg ctctatggtg cggaaggggt gaggccgcgc
    16921 agtcatgagc tattgttggt gcagcttggc gagactgcat ggatcgcgga cgttggcttt
    16981 ggaggtaatg gattacttga acctttgagg ttgatggatg ggtatgagga gcggcagggc
    17041 gccgatcgat tccgcctcct cgcgcaggag caaggcggct atcggctgca atgggagatg
    17101 gagagtgtct ggacagatct ctattccttc gccctggatc cctggctgcc catcgacttt
    17161 gcctttgcca actattacca ctcccattcg ccggactccc tcttcatgca gcgccggatt
    17221 tgcacgatgc caaccctcaa ggggaggaag acgctaatcg acaacctgct caagattcga
    17281 agctcgaatg ggacgcaaga acttcatgtg aagagtgagg gggagcgcca ggcgctgctc
    17341 cagcagcact tcggagtgac cattaacgat cacttgaggt tttgcgattt accgcgccag
    17401 ccatttcacg atcgcaacgc aggccatgta gaggccgagt gagccggcca tcgaaagcca
    17461 gaagccgatc cgttcgacgc cgtagatcat gcagccgaca tagaccagcc agggcggtac
    17521 aaaccagagc aggttcttgg cgtaggtgac gagatgctcg ttgccgccgt tgagataaat
    17581 gaggacgaag gtcgccccgg tcatcgcagg aaaggtgctg gcgaaggcgg cgagaaacga
    17641 ccggccttgt gagccgaggt aggtcgagat actgacgatt gtgccgccca ataagaagta
    17701 cagtccgtac ttcgcccagt cacccatccg caccctcctt cactgtccgc gaaaggcctc
    17761 tcgcgcctcc gcttcgatct catgccctag gcctgtgtac cgcggcgaaa agtgaaacac
    17821 gaccagctcg cgcacctcgg ctttctttgc catgatgccg gcctgcttgg ccgtgaggtg
    17881 gtaccggtcc cgagccttgt ccgcatcccg atccagatag ggggcctcac agtagaagat
    17941 gtccgccccg cgtgcaagct ctatgatctt tcgttcgttg acttcatcgt agcgagcatc
    18001 cacgacatag gcgattttct ggccgcgcgt aatcgtgacg aatcgctcgc ggatctcgcc
    18061 caggatgaac tcgcgcgttt ctttatggtg ttcgtggtag agcgtggcgc agaatcgaaa
    18121 atcgtccggc tgaccctccc agaaatattg cttcacctct ttcagccagt aacccaccgg
    18181 aagcccggct tcatgtaatc gctccttgtt gaagttcaca tgaaactgtt cctgcagcgc
    18241 ataggccaat gaggggatgc ggtgattaag tgccgtagcc tgcacggtga acatcggatc
    18301 acggaatacg gtaaagggcc cctggcccgt gcaaccgttc agcggtgcat ccggttcatc
    18361 gtggcgttga aagccgtccg ttgcgaggaa ggtcgccgtc tggatgccgt cgggatggaa
    18421 ctcgtgcgca gtaatcgtga gcgggtatcc gtccaccagg ttccatgtgt agccgtgaag
    18481 ttttccttga acatttggga tgaggcccgg tggcccgtga cgccgcagag ttttgccgcg
    18541 cccgagggcg acgcgcagca gagcatcaaa cccgatgaag tgatccatat gggtatggga
    18601 aatgaagatg tcgctggccc gcagcagccg tgtcgggcct agggcgtcgt tgtgaccgag
    18661 gtcaaatagg agggcgcgtt tggaccagcg cacttcgacg aacagcccgg ggtcgccgaa
    18721 tacatcattc acgagatagc tggagaagga cgggttcatg ggtgccgcat cacagagcca
    18781 cgaatagtga gtccgtcgtg agtgcaactg ttgcttgaag ttccgttacc ggaacttcaa
    18841 gcaaggtcag gtcaatatgg ttcgcatgac gctatagagg acgataacct ccacagcatg
    18901 ggcgacgatc gtgacataca ggtttctgaa ggcgacccac agacttcccc acaccaggcc
    18961 gtcccagacg gcaatccaat ggagatgttg aaaggttgcc accagaaagg gatcgaacgc
    19021 aaacagcagg gcgctcaatg gtacggcgag ggcggagggc aatcccagac ccagcagccg
    19081 gcctaacaga aaaccgcgaa agttcagttc gaccatggcg gcgatcatga ggatgaacca
    19141 gggcagcatg aggagcagcg gaattttggc gtgcggcgtg ccggcgagaa atcgatagtc
    19201 tgccccaagc cagggcacga gatagaggat caccaggacg ttggctgtgc cgagggcgag
    19261 ccccgttgcg atgcccaagc ggagtcccct tgggatgagg gcgcgcgtga gcccgagcct
    19321 cgtaaccgtt gcgccgttca ggcggctcca ggtcaacagc gcggcatagg cgcaaagctg
    19381 agggaggaac tgatacaggg gctcctgccg aagttcacga ggggacgcgt aatagaggag
    19441 tgtagcaatg aggggaagca gcgcgagggc cgccccccgt tcattgtgct gaatcggata
    19501 cgcggccgac gcctcctcag gcctgatcat gagcagttat tcaagtcgta gactataccg
    19561 ttcgagtgtg gtggccttat tcctggccag gttcgacaag gatttgttgt agtccaccgt
    19621 ggctcgcagc tcgttgcctt gcgccgtggc caggtcacgt tgaaagtcga gcacgaatcg
    19681 cgtcgtactg agaccgacct tcaagcgttc ttgttcggcc tgcaactgct tctcggccat
    19741 gatacgagcc gagcgggtgg tttcgattcg tttgaaatcg gtgtgtacgc ggcggacggc
    19801 ttcccggaca ccgacgatca cttgttgtcg aacgctctgt aaggaggcct gggcattccg
    19861 ggactccaat tgccgtttat tgtaggtgct ataggccgag cggttgccga tcgggtagct
    19921 gaggactaat cccgccccgt aattataaaa gtctccgccg aaattccgtc tcgtggcgtc
    19981 cccgtagtcg gctccaagtc cggacagtcc catcgtccct tgcaccgaca gggtggggag
    20041 caattgattc ttggcaaact tcacattgag gtcgctgctc tccacgttct tgccggcctg
    20101 caaaacttcc gggcggcgtt ccatggcgat atcgatagct tcctgaagac tgatcgcttc
    20161 cagcgaggtg gtcggtggat cggtcggcat aaggcgcaga tcctgccgca gttcttcctc
    20221 cgctggattt aagaggcggc gcagctggtc ttcctgatcg cgaatggatt tttcggccac
    20281 gaggatctgt tcgacacgcg aagcgacggc cgcctccgcc tgcaggacgt cgacgatcga
    20341 catgacgccg gccttggctt tggcgcggtt gctggccagg agttcttccg ctgccttgag
    20401 tgccgcttgc gcgactttca gattttcatt cgcaaagacc atctcccaga atgtctgctc
    20461 gacggtagca atgacagtga gcacgcgatc gagaaacaca tgttgttcga cggtggcatt
    20521 gttttgtgcg atcgaaatga acgtccggtt gacatccgtg ccgaagtttc tcagcagcgg
    20581 ctgtgtaacc gttaacgcga gacccccggt ccaggccggg ttgaacagga aggtgttggg
    20641 cccgctgaca tagctgcgtt gggggctgta attcagatca tagtttgcgc cggtcgggag
    20701 attctgggtg atgtcggcgg tgacgctgga ggtgttctgg tcgaatttgg tgatgtcctg
    20761 caggttggcg ccggtaaatc cgaggatggg tcgattcagc ggcgcgacct gtctgttgta
    20821 ttgaccgttc aagctgatgg tcggatcgaa ttttgcctgt tcaataataa tgtcggccaa
    20881 gcggctttct ttggtttgtc ggccgatatg gatatcgagg ttattctgca gtgctttgag
    20941 gacagcgtcg gccaacgaca tggcttcgcg tcgttcggtc gggacgggtt tggtcacttc
    21001 cagaccgaat gaggtggacg ccgtccagag caacagcgcc gtcgcgccgc cgatgagcag
    21061 acagccccgg agcattggat tcgtcataac aaactccttg atgggagatg caggttgagc
    21121 catactgaat tcatcatgat ggtggcgtgg tatcacaaac ggcgatcagt gtccatgctg
    21181 gcgcgcaagg gcagggcgac catgcgctcg accgggatca tgctggttgc tgtaacagcc
    21241 gcactgctct gggtttcgcc ggcggccgcg caatcggtat caggtgtgcg cggatttaat
    21301 ggaggtgtgg caccgctctt tggtctcgtg ggtccaggga atctctacat tgataaccag
    21361 gggacgcagg gattcatcta caatttcggc aataacttcg aatcgtacaa tttccggaat
    21421 cccacgaccg gtcaggcatg gagcggcgcc gtcatgacgc tggggccgca attgtcggtg
    21481 ggactcattc aaggcgccaa tcagtcgggt tctcccgtgg tgtttcctcc agtgccgcgt
    21541 gagaccgcac ctctgcctcc gattcaatcc ggtctgctcg aggatattcc ctagccagct
    21601 gctgttctcg tcaagaactt ggcctgcgtt cagcaggtgc acgtacactc cgcgtacgtt
    21661 tcctccccat cgtttttctt cttcggatgt ccttgcctct gttcagccac acaatctttt
    21721 cagagtcgga aggtccgtct ttgtggcggt ttggtgtgtg gctgcaagtc tgtcacagcg
    21781 gagagccgta gggctcttca ttatccacag aatccacagc ctgaacgtca cctgtcgatc
    21841 gttgcaaagt ggcgggagga tattcgtaag gcgttgattt ataacgtacg tgttgattgt
    21901 atgcattgcc aattgatgag gaagtcatcg acggtatggc gcttgctttg actccgcgtc
    21961 attgcgatcg atctcctgtt tcgtaacgag acgacaaaaa caatgcgctc ctgtcaaaga
    22021 tgtcaattga atcgcatggg gagaacggaa agaatgccga cagacggtgg gaggcgcggt
    22081 gaagtgccag ccgccggttt tcagcccccg tcaccgagca tctacgatca aaggagattg
    22141 tttgtatgag gattgcccag gtatcgccgc tttgggagag cgtccctccg aaattgtatg
    22201 gaggcactga gcgcatcgtc tcctacttga cggaagaact cgtccgtcaa ggtcatgagg
    22261 tgacgttgtt tgccagcggt gattcggtga ccaaggcgaa gttggaatcc ccgtgtcagc
    22321 aggcgttgcg tctcaacacc ggcattttca accgcgaagc accgctcatt cagatgatgg
    22381 agcaggtgtt cgctgccgcc gaccagttcg atctcatcca ctcccatctc gactttttgg
    22441 ccttttccct ctcccgccgc tgtcgcgtgc cggtggtgac cacgcttcac gggcggttgg
    22501 acttgcccga gcttgtgccg gtcttccgtg attttgcgga gctgccgctg gtttccattt
    22561 cggactcgca gcgccggccc ttgccctggt gtaactgggc caacaccgtc tatcacgggt
    22621 tgccgaaaga tctgtataag ttcaacgccg aaccgggcaa gtacttggcc ttcctcggcc
    22681 gcgtctctcc ggaaaaatgt ccggatcaag ccattgagtt ggccaaacgt gtcggcttgc
    22741 ccatgaagat ggccgcgaag gtcgatcccg cagaccgtgc ctactttgag cgagtggtgg
    22801 agccgttgct cgaccatccg ttgatcgagt tcgtcggaga aatcaccgat gcagaaaaga
    22861 gcgactttat cgggaacgcc atcgggctcg tctgtcccta tgactggcct gaaccgttcg
    22921 gcctcgtatt gatcgaaagc ctcgcctgtg gtacacccgt cctcgcctac cgccggggat
    22981 ctattccaga aatcatcggt catggtgtga cgggcttcat cagtgaaaac ctcgatgaaa
    23041 tggtgagcca ggtgtcgaag ctgggcacga tcgatcgcca tcgatgtcgc caggtctttg
    23101 atgaacggtt caccgcccag cgcatgacca acgattacgt caagatctat caacaactca
    23161 ttgcggatgc cgctacgctt ccgggtaaag ccgggcagca gcacgcttcg aacctctagt
    23221 cagcgcgatc tcaacctcgc ggaaggacca gtatggcaga cgagtcgcag tccactcctg
    23281 aatccaatgt caccggatgg cggttgttgg cgacccgaga ctttggatgt ctctgggccg
    23341 gccaagtcat ctcccaaatc ggtgacggac tgaacaaggt tgcgcttctg tggttcgtgt
    23401 atgaaatgac cgggtcggcg ctcaagatga ccgccatcgg gttattgcag acgattccgc
    23461 ctctggtctt cggtcccctc atcggcgtct atctcgacta tctcccgaaa aaaacggtca
    23521 tgatcgtcgt cgatctgtta cgaacgttga tggtgctgtt gataccgctc ttctacgcgc
    23581 tggatctgtt gacgcttgag cgcctctatg tgctcgtctt cctggtctcc attgtgtcca
    23641 ctatattcgg accggcgttg gcctcggctg tgcctctgat tgtccagcgg tcgcaactga
    23701 cgacggcgaa tgcgtttctg cagagcacta cgaacatcgg cgtcttgttg ggaccggcca
    23761 tgagcggtct gggtatcgct ttgatcggcg cgcaaaatgt gctgtatgtg gatgctgcca
    23821 ccttcctgct ctccgccctc ttcttattcc cgattcgtgt gagagagacc aaatcggtga
    23881 aggagctgga tgtcctgggg actcccgtca tgcaggacat gatggtggga ttccgcttcg
    23941 tcttcctgca gcaccgagtg gtgtttgcat tgatgattac ggccgtcctc tataatctgg
    24001 cgatcagcgc ctttgtgttt ctcctccctg tggtggcaaa ggaactgttg caagtcggac
    24061 cgatggagtt gggatggttg tggtctgccc taggcatcgg gatgctggcg gcatcaattt
    24121 ggttggctcg gatgccccag ggcacattcc aggagcgtat cggcaagatc ggtcgctcgt
    24181 tgacgatcgg gggcctcgcg gtctgcgcgt tgggattgat tcaaactccg gtgttgttca
    24241 gcacgttttt attgatcatc atcatcggtg gtagcacctc cctgttctac ccggtcgtgt
    24301 gggccatgct ccaggaagtg acgcccgaac atctgctcgg gcgggtcttt accacgttta
    24361 gtgtcggtgg gatggcgtcg gccatggtgg gcatggcggg attcggctgg gccgccgaca
    24421 cccttgggcc tgccgtcagt ctcatcggta tcggactgct cctcttgctc actgccatgg
    24481 tcacgatgca ggttagccgt cgtggcctgg tggtgactcc ggctgtcgca taacctccct
    24541 tccaggacga tcgtttcggt ctatgcggca gctcgctggt atgcgccacg cgagctcacc
    24601 ccgcttgacc aatgccggcg atgggcggag ttgctttctg cccctccgtc gcgtatgtct
    24661 tttctctcag gctgttcgaa gacgaatccg ggcctgcctt ctcggctcgg tttactttta
    24721 cacatgaggg gcatatgcct atgcggacta ttcagaccgt gtgtgtggca gggattttgt
    24781 cgtttgtggt ggcgtccggg cttgggagcg tgaggtcgat ggcctcggag ccgcagccgt
    24841 cagagacaaa acccgacgtt gcacctggtt cgggatcgaa ggatgccgaa ggaaagataa
    24901 aggaaccgga tacgaaacca aaagagccgg agtccaaacc gaaggagccg gaggccaagc
    24961 cgactgacca aaaatcaaag gacagcgata cgaaggcgaa agagcctgaa ccgaaggcca
    25021 aggacgggga agcaaaaccc aaaggtcaag aacccaaagc caaggaatcg acgaccaagc
    25081 ccaaggaatc ggaacataag gcgaaggagg gtgagtccaa atcctcgaaa gagccggacc
    25141 aaaaatccaa ggagccggaa gcgaaaccga aggatgccga gattgccgct gagcatccct
    25201 gtccctcggt gccgcaagcg gctgacgcga agccgcaggt ggaagcgccg gtcccttctg
    25261 gtgattccgg tacgggagag cgtcagaaat cggaaccgga acccaagaag ccggtccgct
    25321 catcaatggt gacggccaag ttggccctga tggccgaccc ccatctgttt ccctacgata
    25381 tcgaagtgga tgccaaggat aaagaccttg tcttgttggg aaaagttggg caggagtcgg
    25441 ataagcgtgt ggccaccgat atcatacgat gcctcgaagg cgtgcatgcc gtagaaaacc
    25501 ggctcaaagt cgaggcggac gccgcgcatg ggttgttcgc ggagcgtgac aaaatcatta
    25561 cccaattggt gaaggagcgg ttcgagaaaa gcaaaacctt gcaatcggtc aagttcgatg
    25621 tgaaaacaga ggacggcgtc gtcaccctga acggagcgac gcggtttcag atcatcgtcc
    25681 tcgaagcggc acaggcggca cggcaggtac cgggtgtccg agcggtgaat accgatgcgg
    25741 tccgcttggt cgccggagag taagcgcggt tcatgaggcc gatgccacag gaggttcgac
    25801 acgcagtctg ctgacgctat agaaccggga cgcgcaagcg gcaccgggcc aggacgcccc
    25861 aacgtcaagt ggtcgccgca tctgttgacg cgcgatttca cgctggtctg gtggggccag
    25921 atggtctcac agatcggcga tggcgtgtcg aaactcgcgc tgctctggtt cgtctattcc
    25981 attaccggct ctcctctgaa aaccaccatg atcgggctgt tgcagacgct accgcccatt
    26041 ctgttcggtc ccttcatcgg tgtgatcgtc gatcgtgtcc ccaaaaaact cctgctgatc
    26101 agtagcgact tgattcgagc gttagtgctg ggtgtgttgc cctgcttgct gccggtagac
    26161 tcgttcagca ttgagcggct gtatctcatg gtgttcgttc atgcggtggc gtctgccgtg
    26221 ttcggtcctg ccctgacggc cgcgattcct tccctggtgt cccgccatga attcacggcg
    26281 gccaacgcct tgctgcagac cacgaccagc atcggcatca tcgtcggccc ggcgctgagc
    26341 ggcgtcggca ttgcgacgat gagttctcaa gaagtgctct gcgtgaatgc cgtcagttat
    26401 gtgatatcag cgctgtgctt tttgttgatc cgctttccgc gcacggaaac ggtgccggct
    26461 gcggaggggg gctccctggc cggaaccctg cgggacgtga tggaagggtt tcagtatgtg
    26521 ctccatcggc agcgggtcat cctcatgctc atcggcgcag cctccatgta taccttcgcc
    26581 actagtgcgt tcagcacgtt gtttccggtg ttcggcaaaa agctgcttga tctggggccc
    26641 atcgaagtcg ggtatttgtg gtcggccttc ggtgtgggat tgctcttggt ctcgctggga
    26701 cttgtgtcgc tgtcgtcctg gtcgctgccg aagcggattc aattgatggc ggtgtccagt
    26761 ttcatcagcg gcctaaccct tctgggtttg ctcttcacat cgaaccggtt ggtagccgcc
    26821 gtgctcatgg tcatcatcgg catgggcgcg ggcacgctga ccccggtggc ctggggtgtc
    26881 ttgcaggaaa ttgcgcccac gacgttattg gggcgagtgc tggctatcta caatcttggg
    26941 gcgatgacct ctgcgatcgc cggcatgacg attttcggct gggtgacgca ggaattcggt
    27001 gagcgtccca gcgtatttgg aatcggggtg ggtctgtttt tatcggcggt ggtgtcctgg
    27061 cgagtggccc gatgggtgca ggtcaattgg tccgagacga gcgtgcctgc cgaagaagcc
    27121 gcccggtccg ttgttatggt gacgcagccc acaagtcatt gagtccacat ccgtatcata
    27181 tgattgcacg ggtcgagagg ccctgtccaa agacgaagcg agcagcaggc aggaattggt
    27241 gaggtgtgag ggcacaggcc gcgcccattg catcgatcgt tcagggatga cgggaggaaa
    27301 acgtggaaga aatcattagc gtgaatgatc agttctatat cctggccagt tcatcgatgg
    27361 ccgatgaccg gacgcgtgtg ctcaagcatg gagaaacctt cggtgtgttt gaccggtatg
    27421 gcgacattca accggtaggc cggggcacac aaggcgtgtt ccatcaaggg actcggtttc
    27481 tctcgcggca ggaaatattt ctgaacaatg atcggccgat gctgttgagc tcgacggtaa
    27541 aggaagacaa cgccttgctg gccgtggatc tgaccaaccc ggacttgtat cgggacggac
    27601 gcatcgccat cccgcgcggc agcgtacacg tctttcgctc tcgttttctc tggaatggcg
    27661 tcagttatga gcggtttcgt ttgtcgaact acagcctggc gccagtgaag atgaccctct
    27721 cgatccgatt cgaggccgac ttcgccgaca tctttgaggt gcgcggtaaa aaacgcgagc
    27781 gcaaaggccg catgttgccg aacatcttac ggaaagatct cctggtgctg cgatacgaag
    27841 gtctcgacga agtgacgcgg gaggcccgga ttcagtttgt cccggagccg ttggagatta
    27901 ccgcgtcaca agccaccttc ggcatcgaac tggaaccgaa aggggagata gccgtagcgg
    27961 tcctggtggc ctgcgatgag gtggacagtc atcggccgct cttgtcttat gatgcggcga
    28021 tggcagaagc cggtttggca ttcggcgccg agcagacgga agactgtacc atccaaacgt
    28081 ccaacgcgca gttcaatgag tggtggaacc gttccgtgtt ggacgttcgc atgatggtca
    28141 ccgatacgag tgaaggtccg tatccctacg ccggtgtgcc ctggttcagc acccccttcg
    28201 ggcgggatgg cgtgatcacg gcgatggagt gtttgtggat cagaccggaa ttggcgcgtg
    28261 gggtattggc ttatctggcg tccactcaag cgaaggaggt caatcctgct caggatgccg
    28321 agccggggaa gattcttcac gaaacccgca agggcgaaat ggcggcgctg cacgaaattc
    28381 ccttcgggct ctattatggc agcgtcgatt ccaccccgtt attcgtgatg ctggcggggg
    28441 cctattacga gcgcacggca gacctgccct ttattcaatc catctggccc aatctggaag
    28501 cggcattgac ctggatggat acgtatggag atatcgatcg cgatggtttc gtcgagtatg
    28561 tgcggaaatc gcccaccggc ttggataacc agggatggaa agactcccat gattccatct
    28621 cgcacgcgga cggttccttg gccgaaggac cgatcgcgtt gtgcgaagtg cagggctatg
    28681 tgtatgacgc caaggttcag gcgtcgaaac tggcggaagc gctaggctat gtcgatcgcg
    28741 ccagtcagct gcgacggcag gctcggtcac tcaaggaacg gttcgaggag gccttctggt
    28801 gcgaagcctc gtcgacctat gctcttgccc tggatgggca caagcgcccc tgcgaggtga
    28861 agacgtcgaa cgccggtcac tgtctctaca caggcattgc cagcgatgag catgcgcggc
    28921 gtgtcgcgga gacgctcatg tctgatgagt tattcagcgg gtggggcgtg cggaccctgg
    28981 ccgattccga acgtcggtat aacccgatgt cctaccacaa cggatcgatc tggccacatg
    29041 acaatgcaat gatcgctgtc ggtctcgcgc ggtatggcct caaggccggc gtggaaaaaa
    29101 tcatgaccgg gatgttcgag gtgagtctcg tcctcgattt tcaccggttg ccggaactgt
    29161 tctgcgggtt tgtccgtcgc cccggccaag gcctcacccg atatcctgtc gcctgtaatc
    29221 cgcaggcctg ggcggccgga tccgccttta tggtcctcca ggcctgcctg ggcttgtcga
    29281 ttgtcgcgtc ggaacagaaa gtgatcttca accatccgat tcttccggac tttatcgaca
    29341 agatgcagat caaaaatctg acggtcggca ccgcgtcggt ggacctgttg cttcggcggc
    29401 atgacctcga tgtcgggatc acggtcatcc ggcgggtcgg taaagtcgag gtggtttcgg
    29461 tgaagtagcg cgggcaatac gtggcccgct ccgctgcgtt atggcgcgtc tgccagctgc
    29521 cacagcatgg cgaggacata tcgggcagcc tctgaaagaa tatcagggtt gatagtctcg
    29581 gcggtgtctg tgggctggtg gaaatgggga tgaattccgc cgctcaccac cgtgaccgtg
    29641 ggaatgcccg cctccttgaa cggcacatga tctccgccgg ggaaaaagcc gaagacatca
    29701 aggcggtctg ctacgcctgc catttgcccc gcctgctgcg cggcagcctt atccatcccg
    29761 gtgacaccga tcgtcaggcg tccgttgccg accgctgcgt ggtcgatatt gatcatcccc
    29821 aaggtcgaac gtaagggcgc agtcggctgg ctgatataga atttggatcc caccaacccc
    29881 tgttcttctc cgctgaacga aatcaggaca accgaccgtt tcggctggac cggggcggct
    29941 tgcagcacgc gcgcgatctc cagcagcacg gctgttccgg aggcgttatc gtcggctcct
    30001 gggaacagca ggccgccttg gcgtccaaaa tgatcgcggt gcgcaccgat cacgatcgtt
    30061 tcttctgcct tcgcctggtc gcttcccggt acggtcaaga cgacgttgtg aagcaggccg
    30121 tcctggactg cgctgtgcca acgcatggta acgacggtat ccgtcgcgat cgattgcggt
    30181 ggctggcctt cattgaggtg ttgctgcaac gtccgtagcc gatcctcgtg gcctgttcgg
    30241 tcagtgtgga gtatggccat cgcgcgggtg gtgctgatcc aggcaccggg aatcgtacga
    30301 tccggctccg ttaagccgta aaaggcgctc ggtcgaccgg tgactccgcg gcgagtttca
    30361 taagcattga ggattggtcc ggtggcagtg aggtaggcca gcgccccatg ggcgtgagcg
    30421 gcatgggcct tatccgcatg tgacacctgc ttggcgtatc gctcgggttt gccacgcaaa
    30481 aagagcacga ccttctgacg aacatcgagg cccgcgtatt cgtcgaagcc actttccggg
    30541 tcggagattc cgtatccaac aaacacgacc ggcgcctgca cgtcggccga aggggagtcg
    30601 aggacgggaa ggtaatcggg gccgatctgg tccggcggcg aatcggcact gcccgccagg
    30661 cgcaggaacg aatccttgcc gatgatcgtt ggccgatggg aagtggactg tatgcgaatc
    30721 gatgcatggg cgggagaacc cttgctgcga gattcctgca agggaggctg tgagctgttc
    30781 gattccagga agcgttgccg tacgaattca gcggaggcca ggtcgtcgga ggtgccggtc
    30841 tggcggccat tgaaggttgg tccactcagt gttcggacat cctccaccat gcgttggctg
    30901 gaaacgagct ccaaggattg tctgagcgac tgaggaactt ccagctggtt ctcggccagc
    30961 accgtcacag gcgtcagcgc aatccagagg ctgaggatga gttgacccac taaattggag
    31021 tgatggcttt gggcggacaa tgaggctctc ctgctgtgag gacctacgtc agcgaatggc
    31081 gtcagatcga agtggcgtgt gctttctggg ccgaccaacg ttgataccag cgccagaggg
    31141 gtcgttgcag aaactgtgga agcggatatc ccagtcctcg agtatagccg tcatctcgat
    31201 cgagtacggc gaacgcccac tcatatttct tttgaaaggc tgcgcagcgc tcctggattt
    31261 cttcggtgct gagtggaatg tgttgccgaa gggccgcccc gatcgcctca tcggaggtca
    31321 tgtcacggac aagcgactcg atctgggcgg gcgtgagccg gaggtggcgc atgaaggact
    31381 ggtccaatgc tgaagggtag gcataggcgc cgagcgtgcc ggcctgaaat gcccgcacct
    31441 tgtcgatcag gcggggtaac cagatcaatc cggccgtggc gtcgctccat cggcggggtg
    31501 gatgctgtcg aagatccatg cgtgatccag gtttcagctc aatgaggcgg ccttcggaat
    31561 gaggcactat agcataaggg aagagccccg ttgcagagag caaagggctc aaggtactat
    31621 cggttcccgg gccggcaaag gatcagtatt ccgctgcatg aggcggtccc ggatcgcaac
    31681 agcagctcga ctgataacgc aaagggaatc agctatggca gagcagggaa aaggtctcta
    31741 cgactctcag tacgcacggt ttcgagacaa tcaggggaca catcagggct atgaatttca
    31801 gcacgggccg gcaggcagtg tgcctccgcc cgtggttacg ttcatggata aaataaaatg
    31861 gtggacgtta cgcggatggc gacggaagaa gatcttggct gaacgtgatc gatatcagca
    31921 ggacatcatc cagatcaaaa cagcacatcc gaaatcgtga ggtccactcg aggaggagta
    31981 cttccgtgca ctatggatat cagcgcgtca ggcagataca ggtaggtcgg aaaaatcagt
    32041 ggggtggtgt cacatcgttt gtcagggccc tgcgatatgt tggcgtggcg gccgtcgtgg
    32101 gtgtgttggc gggtgggatg gagacggcat gggctgtgcc gaaggaaacc tccacggaaa
    32161 aagcggagca tttgcggcaa caggccaatc cccaactctt caacgattgg acgtttgata
    32221 aagatgaagt cggggccatt cccaaggggt tcgtggccgt gacctccggc gatcaacggc
    32281 caggttcgtg gaaggtcgag gcgcaagcag ccgtgccgtc tgctcccaat gtgttgctcg
    32341 ggacatccgg ctgcggagag tgtcaggaaa ttcttgttgc gcagggattt cagtatgagt
    32401 accccgatct ggtcgttcgc attcaacagg ggggcggggc tgccaccggg caggtgggtg
    32461 tcgtgtttgg gatgaaggat gcccagaatt actacgcgac tgtcgtggat gtgtctcaga
    32521 aaattattca ggttgtgcgc gtgatcgagg ggaaagagtc agtcctcggc cgggcggcaa
    32581 tcaagccgaa gccggttgaa tggcacaccc ttcgcgtaca gcggaatacc attatcagca
    32641 aggatttcgt cgaaacattc tttgacggaa gtctggcctt gtccgtggaa gatcaggcgc
    32701 ttggagtggg gcaggtgggg gtattggtga ggggggagtc gtcggcacgc ttcgataatt
    32761 tcaatgcggc ccccttatat tccagccgac cgttgtctgc tccggcggcc tattgagcca
    32821 gcaaaagtga cattcggccg gatcggatag atttttggcg agacgatttc gcgcttgcct
    32881 ttcccatttt ggtgcgatac agtgaaggtg cttcattgcg aagagccttg gcgatgaagt
    32941 agaaaaagaa ttacagggct cgtgtcgatg ttgttttggg ttcttcccgg gaatttcgga
    33001 agccagagct aagattgccg ctgtgtttgc atcttcgccc cattccttcc tcgtttcttt
    33061 ctcgagtccc agacaacacc attctattct caaaggagga acccaatggg ttcgaagatc
    33121 tacgttggcg gcttgccata ttcaaccacc gaacaacagc tgagtgacct gttcgcggtg
    33181 catggcgcgg tgacgtctgc gcgcatcatc acggacaagt tcaccggcca atcacggggc
    33241 tttggtttcg tggaaatgtc gggagattct gaggcacagg cggccatcaa tgcattgaac
    33301 gggacacaat tcggtggccg caccttgacg gtcaacgaag cccgcccgca ggagccccgc
    33361 tccggtggcg gtggacgtgg aatgggcggg ggccggcact aagctgcgcc cgtttctata
    33421 tacctattca ggggctgccg acagggtagc ccctgcgttt ttcttaccgt gttgtcctct
    33481 ctttggtctg cagggccatc aggttgtctg cccctgtttc cccagataga gatttaggag
    33541 tgtcgttgca tggtgtcgtt tgccgaattg tctcttacat cgtttctcgc tgaccgttta
    33601 cagcaggccg ggtttaccgc gccgactccc attcagagcg ctgcgattcc tctggcgctg
    33661 caggggcgtg atctgttagc ccaggccaaa acggggagcg ggaaaacgtt ggcgtttctc
    33721 attccgttga ttgaacgtgc cgtcaaggaa gggtggaagc ctgccggcca tgcgtccgcg
    33781 caaaccgggt cgtcacggtc gccgcgtgcc ctggtgttgg cgccgacccg tgagttggcc
    33841 ctccagattg aaatggaact gcgcaagtat gcgccaccgg cggtgacgtc gctggctgtg
    33901 tacggcggtg tgcccatcga gcggcactac cgtgccctcc gtcagccgcc gatgatcgtc
    33961 atcgggacgc cggggcgtct gctggatgtg gccggcactc ggcatttgga tttgcgcggc
    34021 atcgaatatg tcgtgatgga tgaagctgat caaatgctcg atcgggggtt cctgcgcgac
    34081 atccaacgta ttttacagct gcttccctct cagcggcaga ccatgttgtt ttcggcaacg
    34141 ttctcgccgg agattctcac gctggcagaa tcgatgctga agaatcctgc tcggacggcg
    34201 gtggatcccg gcgtcaacac gccaaccacc atcacgcatg cctattacgt ggtgcccagc
    34261 gaagcatcgc gggtgcagct gattcatacg ctgctgcaat catcggaagc cggtgatcag
    34321 tcgatggtgt tttgtgacca gaagtacaaa gtgaagcgcc tggctgcccg gttgggcgga
    34381 gaaccggctt cggtgggggc tattaccggc aatcactcgc aggcgcagcg tgagcggacg
    34441 ctgacggcgt tccgttctgg tcggttgcgg tcgttggtgg ccaccgatgt tgcggcgcgc
    34501 ggattggatg ttccgaccgt ttcgcaggtc attcattatg agttgcctgg caacccgact
    34561 tcgtacgttc accgtaccgg ccggacgggc cgagcggagc gatccggcgc aaccctcttg
    34621 attctctctc cgcaagagga gcatgaatat ttggccatgg tgcgacggtt gcgaatccaa
    34681 acgaagcgcc tgacactgcc gaccttggca acgttgccgc ctcccgcgcg tgagacggag
    34741 tcgaacagcc atccccggca tgatggacac gggcgtgatg cccggccgcg tcgttccgga
    34801 gatcgcccta actccacgag ccaggacgcc agagggggac agggacgtcg cggatggcgt
    34861 gccggtcgtc ctgccgctcc gcgccgcggc aatagttgat gcagtatttg gccggatgga
    34921 aatgctgtcc ggcagattga ggaggatgcc gcgatgagtt ctgcacggaa tctcttgctg
    34981 agcatgatgg tcgccgccgg ttgtcttgca gccggcgagg gcgccttcgc gcaaagcgat
    35041 cttgccattg ccgacggcat gaaggtgtcg ttggagtata cgttgtcgct tcccgacaaa
    35101 agcgtggccg attcgaatgt cgggcaggag ccgataacgt ttgtgcaggg ggcgcatgaa
    35161 atcgttcccg gcctcgaaaa ggcgcttgac ggcatgaagg ccggacagaa gcggcgtatc
    35221 gatgtgtcgg cacaggacgc ctacggcccc tacaacaata agctgcggca aagtatcgat
    35281 aaggataagc ttcccaagga cgtgaaggtc ggggacattt tgcaggcttc ggacaaccgg
    35341 ctggtcaaag tcttggaagt gaatgacaag aaagttctga tcgatctcaa tcatccactg
    35401 gcaggaaaga cactcacgtt tgacgtgaat atcctcaagg tggaaaaagg cgatgccgcc
    35461 gacgttcctg agaagaaaaa tccctgaccg atcgcaatgc acctaagcgg tgagcaggcc
    35521 cgctgatcgg gctggttgta ggttctcgcg gtaagatgcc ctccgactcg ccgtggcgat
    35581 cagcgtcacg gcggcacagt gtgcgttcga gtctcccttc aacgatgtaa acgcgatgtc
    35641 atttcagagg tggcgtgtct tcgagacatg ccccgaagat catggcgtcc tgctgctcgg
    35701 tcacatcgac agtcggcaaa cttcatcggg ttttcaggcc gggcgattta gctggcgcgc
    35761 atgttaagat gacgtgatta tgcccccgtt taagctcgat gctccattca aaccctgcgg
    35821 cgaccaaggc caagcgattg acaagctgac gtccggaatt ttggccggca agcagcatca
    35881 agcgttgctc ggcgtcaccg gttccggcaa gaccttcacg atggcgaatg tcgtcgagcg
    35941 ggtgcagaag ccgactctcg tgctcgttca caataagacg ttggccgggc agctctacca
    36001 ggaattcaaa cagttttttc cgcacaacgc cgtcgagtac ttcatcagtt actacgatta
    36061 ctaccagccg gaagcgtaca ttccgcagag cgacacgtac attgcgaagg atgcctcaat
    36121 caacgatgct atcgatcaga tgcgccatgc cgccacgaca tcgctcctgc agcggaatga
    36181 tgtcttgatc gtctcgtccg tttcctgcat ctacggcctc gggtcgccgg aggtctacca
    36241 tgacatgttg gtctatctcg aagaggggat ggagacgcgc cgcgagaaga ttctggccaa
    36301 actggtcgat attcaatatg cacgcaatga cgtggatttc caccgtggaa catttcgcgc
    36361 gcgcggcgat gtcatcgaga ttttcccggc ttcgtcggaa gccaagtcgg tgcgcatcga
    36421 gctgttcggc gatacagtcg atgccatcca tgagatcgat ccgctgaccg gaaaatcgct
    36481 gggcaagctg ccgaagatcg ccatctaccc caatacgcac tacctcattg cgcccgatcg
    36541 ttacgaacgg gcgattaccg gtatcgagga ggagcttgag gcgcgagtgg ccgcgttcag
    36601 gaagaacggt cagttattgg aggcgcaacg gatcgagcag cgaaccaaat tcgatctcga
    36661 aatgattcgt gccatggggt attgccacgg gatcgaaaac tattcgcgcc atttgagcgg
    36721 gcgtgcaccg ggagatccgc cgccgacgtt gctcgattat ttccccaaag actttctctt
    36781 gatcatcgat gaatcgcacg cgacggtacc gcagatcggc ggcatgtacg aaggtgacta
    36841 ttccaggaaa cgcacgcttg tggactatgg cttccggctg ccgtctgctg tcgacaatcg
    36901 tccgctgaag tttgctgagt tcgaacagat gctcaaacag gtcatctatg tctcggcgac
    36961 gccgggcccc tatgaactgg agcatgcgaa gggtgaagtt atcgagcaga tcatccgccc
    37021 gaccggctta atggatcctc tgatcgacgt gcgatcggcg aaggggcagg tggacaatct
    37081 gttggcggag gtccgggcgg aagcagcgaa gggcaatcgc gttctcgtga cgaccttgac
    37141 caagcgcatg gccgaagacc tcaccgagta ttatcatgac ctcggggtga aagtgcggta
    37201 tctgcactcg gacattaaaa cgctggagcg ggcggaaatt attcgcgagc tccgatgcgg
    37261 cgtgttcgat gtgctggtcg ggattaacct gttgcgagag ggactggacc ttccggaggt
    37321 cggattagtg gcgattctgg atgcggataa ggaaggattt ctccggtctc atcggtctct
    37381 gattcaaaca gccggccgcg cggcgagaaa tctcgatggc cgagtcattt tttatgggga
    37441 tacggtgact gactcgatgc ggagcgcgat ggatgagacg gcgcgccggc gccatatcca
    37501 ggaggcatac aatgtcgcga atggcattac gccggaaagc attaagaaac tgatcccggt
    37561 gctcgactat gcgtcgggag gaacgaatgc cggtcagctt gagcttgcgg cggaatcgtt
    37621 ggcggactat gcgcccacag cggatacgga gcaattgatc cggcgtctgg aggtcgagat
    37681 gaaagccgcc gccaagaagt tggagtttga acgggcggca gagttgcgga accgaatcag
    37741 gtccttgaag ctgaaagcgc tggagttcac cgagtaacga tcgagctgcg agacggcgac
    37801 ggttgggaat ggcctcaact tacatctgct tgtagagata ggctcccagg aacattccta
    37861 acacgctaag cagattgacc ttaatgctga aaccaaaggt cagtttgagg agaaccagat
    37921 ccaccgtgag gggtgggttg attccgggag agaaattgct ggcaaagatg ttttgaatcg
    37981 cgccgttcgg ggccatcacg cgcagaattt caccaaaaat cccgcccagc attccgccga
    38041 tcaggataaa gatcagcagc acgccgatcg attttctcat ccgatgtctc tcccggttca
    38101 cactgtcggc ggtatgtgcc gacttgaggc accatatcgg aagcgtaaaa tgatgtcaac
    38161 aaaatgcatg ccagatgcta gcagtggcgc atgttcctgg cgggaaaggc cctgccgtgc
    38221 tccacggtgg aattctttct tcgccgttcg gtcccgcgcc ctatatcacg accgtttttg
    38281 gctggccgag ggctggcggt gatgtcgaga caggtgacgt ggcgagtctt ccggacgtcg
    38341 ccaatagagt gccgaatatc ttgacttcac gcgccgccct tctatagact gcccgatgct
    38401 atttttttga tgtttttcga ggcgatcgga gctctggctc gaacccggct tcgatggcct
    38461 ttttgtttgg tgattggtgc ttgacgcgct aagcgaaaaa tttgaacgga tcctcaagaa
    38521 gcttcgtggg caaggtgtgc tcacggagga gaatattgcc gaagcgctga aggaagtccg
    38581 tctcgcgttg cttgaagcgg acgtgaattt caaagtcgtg aaggattttc tggatcgcgt
    38641 tcgggaaaaa gcgatcggtc aggaagtgct gaaaagcctg acgcctggtc atcaggtcgt
    38701 caaagtcgtg tgggacgagc tccgcggcat gatgggcgga gaacggtccg gtatcagcct
    38761 tgcctccagg ccgccgacga ttctcatgat ggtgggattg cagggagccg ggaaaaccac
    38821 aacctccggc aagctggccc gtctattcaa gagtcagggc aaacgtgtgt tgcttgtggc
    38881 ggccgacccg cgtcgccctg ccgcaggcga tcagttggcc agcctcggtc atgacctggg
    38941 tatcgatgtt caccgatttg atcaagtcga tgcctcgcgc gctgatgttg tccgtatctg
    39001 tcagcgcgga gtggagcgcg ctcaggaaca aggctacgac ctcgtggtcc tcgataccgg
    39061 cggtcggttg cacgtcgatg acgaattgat ggccgaactt gtggcggtca aagaggccgt
    39121 cactccccac gaggtgttgc tggttgccga tgcgatgacc ggtcaagatg cggtcaatat
    39181 ggctggccag ttcgaccggc aggtcggtct caccggggtg atcctgacga aagtggaagg
    39241 tgacgccagg ggcggcgcag ttctgtctat ccgggccgta accgggaagc cgatcaagtt
    39301 tctgggtatg ggcgaaaagc tcgacgcctt ggagccgttc catccggacc ggatggcttc
    39361 ccgaatcctc gggatgggcg atgtcctttc gttgatcgaa aaagcgcagg agacgttttc
    39421 gcgggaagag gcggaagccg cgcaaaagaa actgacgagc agtacgttta cgttggaaga
    39481 cttccgctct caactgggac agatgaatcg gctgggatct ttcgagcaga tcctggggat
    39541 gttgccgggc ggacagaaat tgaaagatct cgcgaacagc gggttgccgg aaaaagaaat
    39601 gaagcgggtc gcggccatga tcgattccat gaccagccgc gaacgacgcg atcacacgtt
    39661 gatcaatggc agcaggaaaa aacgaattgc acgcggcagc ggcacgagcg tgcaagaggt
    39721 caaccgtttg atcaagcagt ttttgcaggc gcgaaaaatt gccaaggtca tgtcgggcgg
    39781 agcaggtggg cggcgtcagt tggcccagat gcttcgggga atgtgaccgg agcagggtaa
    39841 gagctgcgta ctcactgggg aagaagagcg tgttaaccga gcagacccag ccatggctga
    39901 gggctcatta ttgtaggagg ttctaagtgg cggttcattt acgattggca cggacgggac
    39961 gacacaagcg accgatgtat cgagtcattg cagcggattc acgtaagccg cgcgacggcc
    40021 ggtttttaga aatcctcggc attttcgatc cactgaagaa tccggccgtg ccggtattaa
    40081 agtccgagcg ggtgctttcg tggttgcggc acggcgctca gcccacgacg acggtgcgaa
    40141 cgctgttgaa acggcacggc gtctggaagg aattcgagac tgagaagagt gcgaaggctg
    40201 aaaagccggg aaaagacgag aagagcaaaa agtaggcgga gctcatgacg ccgctcgatc
    40261 aggcagagct tgtgaccatt ggaaggatcg aacgatcctt cggggtgcga ggcgaagcgc
    40321 gcgtgcggtc cctcagcgat gtgccggggc gatttgaggc gcttcgcgag gtgaccattg
    40381 ttgcgtcgag cggcaagagt cttgtgaccc gggtgacgca tgttcggtca ggtgggccga
    40441 cattgatcgt ggggttcgaa gcgttcacga cgccggagca ggtcgccgag tttcgcggtg
    40501 gactgttgca ggttccgcgt ggagactcgc cggcgctgcc gtcagatcag tactatcaat
    40561 gcgatctgat cgggatggtt gtccaggatg aagccggaac cgtgctgggg cagctggaag
    40621 aggttctggc tatgtctgat aatcaggcat tcctcgtacg gcaggatgga aaagaactgc
    40681 tgattcctgc ggcaaaacaa atcgtgctgt cggtggatgt cggaaaacgg gtgatgaccg
    40741 ttcggctacc cgaagggttc ggagatctct aatatgcggt gcgccgttct gacattattc
    40801 cccgatatgg tggcaccggt gcttggccag agtattctca agcgcgccca ggaaaaggga
    40861 ttgctggagg tttccgttca gaatctgcgg gactatacgt tcgaccggca taaaacggcg
    40921 gacgatgtgc cgtatggcgg tggcgcgggc atggtcatga aagccgaacc ggttctccag
    40981 gccgtcgatg cgttgcgcgc ccggtatcag gcgtctcatc ccgagaccgc cttgcgggtg
    41041 atcatgccgt ctccacaggg acggccgttt acgcaagcgc ttgcgcagtc tctggcgaag
    41101 gatgaccgtg tgctggtatt cgtctgcggg cattatgaag gcatggatga gcgtgtcaat
    41161 gtggcgctgt gtcctgaaca gatctccgtc ggcgactatg tgttgaccgg tggggagttg
    41221 gcggcgatgg tcatgatcga cgccgcggcc cgcttagtcc ccggtgtact cggtgatgcg
    41281 gcgtcagcgg ccgaagagtc atttactgaa gggttgttgg aatatccaca ttacaccagg
    41341 cctgcggagg tgcgcgggat ggcggttcct gaggtgctgg tatcggggca ccatgaggtg
    41401 atccgcttgt ggcgtcgcaa agaagcgttg cgcaacacct atctgaagcg gccggatctt
    41461 ttgcgggatc gcgagcttgg attagaagat caacggttat tgagtgaagt gatgcaagag
    41521 agtctagtac aggtacctgt tcgttagagg aggagagaga ttatgaatcg gctagagcgg
    41581 atccaacgat ccttaaccaa aaaaacggcg cccaagttcg agatcgggga taccgttcga
    41641 gttcacgtga aggtcgttga aggtgaaaaa gaacgtatcc aggtgtatga aggaacggtt
    41701 atcgccagaa aagggacgct gaatagcgaa accttcaccg tccggaaact gtcgtataac
    41761 gttggagtgg aacggacctt cccgatccat tcacccagtg tggcgaaaat tgacgtcgtc
    41821 cgccagggac gagtccgccg cgccaagctg tattatttgc ggacgaagaa gggtaagttc
    41881 gccaaggtgg aagaccgcga gttcaaagtc gaaagcaagg cgcaggctgc agcgaaggtc
    41941 gaagctgccg ctgccgcaaa ggcctgacaa ggcccttcgt atacgctcag gacagaggca
    42001 cacgtttggt tggtagcctg aacccgacga cagggggacc caccgaggaa tttgaggtgg
    42061 aggctcggtc gcgcgggtac cggcatattg ctggtttgga cgaagccgga cgtgggcctc
    42121 tcgccggtcc cgtggtcgcc gcggccgtat tattgccgag acggtgccgc ctaccgggac
    42181 tcaacgattc caaacagatc atcgaagcgg accgtgtccg gctattcgat gaaattgttc
    42241 gacgggcaat cggtgtcggc gtcggcgctg cgactgaggt ggagatcgat cgcctcaata
    42301 ttctccaagc ctccctattg gcgatgcgtc gggcgttgat ggcgcttccc ctgcaaccgg
    42361 actttctgct cctggatgcg gtcacgctct ccggcctctc aattccccag cgtcccatca
    42421 tcaaaggtga tgggctgtct tgttccatcg ccgccgcctc aattgttgcg aaggtcacgc
    42481 gcgaccgcct gatggtcgaa tatcatcggt ggtatcctca atacaatttt gcagagcata
    42541 aaggctatgc cacgccggag catcttcgtt tgctccgcga gcatgggccc tgtgcaattc
    42601 accggcgaag tttcgcgcct gtacaacatt gctttgcaga ggatgacacg gtctcccttt
    42661 cgctgtcaga tgagagtgag agcctgttcg actgatgcgt gatcgacgcc gtctcctcgg
    42721 agatgaaggg gaaggtcaag ccgaagccta tcttcgccga caggggtatc gcatcctggg
    42781 ccgcaatgtg cgctcccctc taggcgaatt ggatttgatc gcggacgacg ccggcactct
    42841 ggtatttgtc gaagtcaaac gccggcgatc aggggcctat ggcggcgcga tcgaagcggt
    42901 agatgcccgc aaacgtgcca aattgattca actggcatct cactatctcg cacagcatcg
    42961 attgcacgac cgtgcttgtc gcttcgacgt cgtattgatc caggacgacg ccggatccgg
    43021 cgcagccgtg cagcatattg cgaatgcatt cgacgtcgca ggggatgatc tgcgatggta
    43081 ggatgccgtt gagtgtctga agtgttgcgc cgggcctgtg ccatcccagg cggaaagggc
    43141 cgacctcgtg ctgcattctg accgctaccg ttgacaccat tcatgattca actttttcac
    43201 gtttcaaaat actacgaccg ccgccccgcg ctttccgatg tcacactgga aatcgagaaa
    43261 ggcgaatttg tcctcttgat ggggcccagc ggtgcgggaa agtcgactct gctcaagctg
    43321 ttgatcgggg cggagcgccc ggaagagggc cagattctcg tgcagggtcg aagtctctcg
    43381 aaactgcgtc cgtccgaaat tcccgtcctg cgtcgtaagg tgggcattgt cttgcaggat
    43441 ttccggcttc taccgaaaaa aaccgtgttt gagaatgttt cgctgccgtt gttagtccag
    43501 ggtgcatcca cgacggaaat ccggcgcaaa gttgcagagg cgttgcgggc tgtcggtctg
    43561 gatcataaaa aagatctgtt tccgcccggc ctgtcaacgg gggagcaaca gcgcatttgt
    43621 atcgcccgcg cgatcgtcaa cgggccgatc atgctgctgg ccgatgaacc aaccggtaat
    43681 ctggaccctg agttaacgag cgaaatcatc gagctgttca agtcgatcaa tgcacggggg
    43741 acaaccatca ttgtcgcgac gcacgatccg aatgttttgg cgcaggtcaa tcgacgggtg
    43801 atcaccttgg aacacggaaa agtggtgtcc cgggatcagg gggcatcgtg agacgcctgc
    43861 tgtatctttt gcgagaggcc gtggccaacg tcttgaccaa tcggaccacc accctggtcg
    43921 cggtggcgac gaccgccttt acctttgcct gtgtcggggt atttttgctg ctctacgtga
    43981 atttgagaac catggcctct tctctcgagc aggatattca ggtcatggtg tatctgcagg
    44041 atgacctgac tgagcaggcg cgaagcgaaa tagaacaaca attgaagatt gatcgagcaa
    44101 tcgcctcgtt gacctttgtc tccaaggaac gggcgctcgc tgattttcag gcccaatttc
    44161 cgtcggagtc gcgtctcctg caggggctcg ggcaaaaccc gctcccggcc tcattcgttg
    44221 tcctgatggc cccggagtct cgttcctccg acgccatgcg gcgatgggct aatcggaccc
    44281 aactgattcc cggtgtcagc caggtccagt ataaccagga gtgggtggaa gccctggctg
    44341 gcattgtccg gtacattgag gtggcggcca tcattgtcgg cgtaattctg tcggccgctt
    44401 cggtgaccat tatcgccaac acgattcgtc tggccctgta ctccaggcga gaggaaattg
    44461 agattctggg tctgatcggg gcgagtacca cgtttatccg tgtgccctat ttgctggaag
    44521 gtgccgcatt gggtttgtgt ggcagcgccc tttcgctggt gatcttaaaa ggcggattcg
    44581 aattgttccg gcatcaaatt cattctgcca cgcggtttct gggggtcgat gcgctcctga
    44641 cgtttttttc gttcgacatg tgcctggtgc tcatgctggt ggggctgttc ctgggatgcg
    44701 cagggagttt tctctcgctg ttgcgttttg gcgaggggcg ggcatgacgc gcattcagtg
    44761 ggtatgggtg gtgttgagcg tccacctggc attgtcgacg agcccgccgc ctgcacatgc
    44821 cgaacgcaag gattcgtatg ccgacaagat cgagcaggaa aagaaaacgc tggagaaatt
    44881 acgcggaacc attgtcgaga agcgtaagaa ggccgacgag gccgagaaaa agcgcgagtc
    44941 gatactacag gggctgcaat cgctggatga gcgtctcgtg cgttaccggc aagaacacca
    45001 ggataccgtc agaaaactca aaaaaaagga tgtggaaatc gagcagatga gcgtgcagct
    45061 gagccgtctg tccgagcgga tcgatgaacg gcaggatgcc atcgccgcca ggctgcgggt
    45121 tcagtatgtc gagggaaggt tttggcaact gaagaccctt ctcgccgcca gttcatccgg
    45181 cgactttcag cgccggtttc ggtatctctc cgccgtgacg caacgggaat atgagatcgt
    45241 ggagggctat cggaaggacg ccgaacggat cgccgaagtg gaacggagcc gtgaggaggc
    45301 caggcagggt attctccttt ataagatcag cacggaagaa aagctggctc aaattcaagg
    45361 gctcaagaag cagaaacgcg tctatcttgc gaaaatcaca caggaaaagg agtcgcatga
    45421 tcgggcggtc gaggagctgg agcgatccgc gagccgagtc gacagtttat tgaaagagct
    45481 tgagacccgg cggcgggccg ccttggcaaa tcgtcctccc tccgccggag cagggcttcg
    45541 ggcattacga gggacgctct tgtggccgac ggacgggcag gtggtctcct actttggccg
    45601 ccagaagcat cccaccttca acacgtatgt tcaacgaaaa gggattgaga ttcgcgcagc
    45661 agaagggagt attatacgat cggtgcttgc cggtcaggtt gtctatgcgg actggttgaa
    45721 aggatacgga ctcgttataa tcatggatca tgccaacggg gtgttttcac tctacgccca
    45781 cgcatctaaa atcttgacgt cggtgggcgc ccgaattgaa gccgggaatg cgatcggtga
    45841 aacgggcgac accggcatga caggtgaaaa tacgctgtat tttgagctgc gcgagggggc
    45901 ggaaccggtg gatcccctgg tgtggctgtc aaagcggtag gcctcggaag gaaggaaccc
    45961 acgtatggaa cagcggcgga gccggcggtg gttatatctt ttgctgatgg tgacagtagc
    46021 gctgggagtc gggatcgtgc tggaaaaggg tttggagcgg accggccacg cgtctgaaac
    46081 ctatgaagag ctgcgcacct tttccgaagt gttgacgcag gttcaaaaac actatgttga
    46141 cgacacgaag gtgaaagacc tcgtgcaagg ggcgattcgt ggaatgctgt cgacgctgga
    46201 cccccactcc gcgtatatga cgcccgagat gtataaggag atgcaagtcg agacgaaggg
    46261 tgaattcggc ggcgtcggca ttcagatcgg cgtgaaggaa aatcggttgg ccgtgatatc
    46321 tccgatcgag ggaactcccg cgcacagagc cgggatcaag gccggtgatt tcattaccaa
    46381 ggtgaacgac gaacccacca aagacctgac gttgatggat gcggtgcaga agatgcgggg
    46441 gccgaagggc accaaggtga acctaacgat tcagcgggac ggcaccgcgg atccgctcgc
    46501 cttttcgttg gttcgcgata ccatcaagat tgaaagcgtc aagttcaagg tgctcgataa
    46561 cacgatcgga tacgtgcgat tgacccagtt ccaggaagcc acaggaagag atctcgctcg
    46621 ggcattgaag caattcaaag agcaaaaggt ccaggggacc atcctcgact tgcggaacaa
    46681 ccccggtgga ttgctgacgg cggcggtcga tgtatcggag cagtttgtcg gaaatggaaa
    46741 actcatcgtg tatacaaagg gacgcgaggg gaaaaaggac gagtggttct ccaagaccaa
    46801 ggagacgctg gaggattccc cgatgatcat cctcgtcaat gaaggctctg ccagcgcatc
    46861 cgagattgtt gccggggctt tgcaggattg gggacgggcg gtgatcgtcg gaaccacctc
    46921 gttcggcaaa gggtccgtgc agaccattct gccgctcggc gatggctcag ggctccgcct
    46981 gaccacggcc aagtattaca cccccaaggg gcgctcgatt caatcgaccg ggatcacccc
    47041 ggatatcgtc gtgaaactgc agacgcagac tgtcgcgaaa gcgggcgaca aggatgcgaa
    47101 agaagctgag ccgaagacgg cgaaggctcc ggcctccggg aaagactcgg cttcttccaa
    47161 gccagcggat gaaccggcgc ataaaaatgg cgcggcctca ttgaacgatg caggcgggga
    47221 tatctccgtg gaagatgatg ttcagttgca aaaggcggtt gaattgctga agacctggaa
    47281 aatcttcaag gagcttcgac cggcggcgta acagcgtcag aggcacgctg ccggcggatg
    47341 gccgccagca ggtcatcctc cgatcccgaa aatcctggtt gcgtcctcaa gaggtgggac
    47401 gcaaccaggg attccaaatc cgctaacgag cgaatattca gccggaaata gagatagctc
    47461 accagcgcgt cagacaggcc cggcaatgag gcccattcag cgacttcctt cggtaacgga
    47521 gttctgagtt cttcataggc gcgaatcgtt cccgtggtga gaaactcttc gatttttcct
    47581 gccaggtcct tgccaattcc gggaatctcc tgcaactgac gacgagccgc caaatctgtc
    47641 aggtctccgg tgatcatcag gatggcgtcg gccgctttac ggtaggcgcg cacccggtag
    47701 gggttggccc gttgggctgc cagtaggttc gccatggccc gaaaaatctg ggcgagttga
    47761 ttgagacggt catccatcgt gaagagtggt atcgagcgtg atggccatat tgtggaggga
    47821 atgcctgtca aacggcaagg cctatcgccc ttggttgaca accggttttc ccgtttcata
    47881 ggatgattcg acacattcag gagcggttgt gacgatccag gtgaatgggg aatctcgcgg
    47941 catcggtgac ggacatacgg tcgcggcgtt gctgcgcgac ttggacattc gcgctgaccg
    48001 agtggctgtc gaattgaacc tggagatcct ggaccgcaag gatttcgaaa ctcgcggtct
    48061 ctgcgaaggg gaccgagtgg aaatattgag cttcattggc ggcggagcgg aatagggatg
    48121 gatacgatga atgatcggtt ggtgatcgcc ggcagggaat ttcaatcgcg tctgtgggtc
    48181 gggacgggga aatataaaga ttttgccgag actaaaaaag cgatcgatgc ttccggcgcc
    48241 gatgtggtga cggtcgcggt gcgccgcgtg aatatcacgg atcgttcgaa ggaaaacctc
    48301 ctcgattatc tggatccgaa gaaatatatc atcctgccga atacggccgg ttgttacacg
    48361 gtggaagatg ccgtgcgata tgctcgattg gcacgagcgg ccggcgtctc tgatctggtc
    48421 aagctggaag tgatcggcga cgaaaagacc ctctttcccg ataccgcagg attgatcgaa
    48481 gcggcgaaga ttctcatcaa ggaaggattc atcgtgttgc cctatacgaa cgatgatccg
    48541 atcgttgcca agaaactggt ggacattgga tgccctgcgg tgatgccgct ggccgccccg
    48601 attggctctg gtctcggcat tcgaaatcca tacaacctga aaatcatcat ggaaacggtc
    48661 aaagtcccga tcatcgttga tgccggggtg ggaacggctt cggatgcggc acttgccatg
    48721 gagtatggcg ctgacgcggt cctgatgaat accgccattg ccggcgctca ggatccgatc
    48781 gcgatggcgg aagcgatgaa atatggcgtg tgggccggtc gattggcgta caaggccggc
    48841 cgtattccgc gcaaactcta cgcgacggcc agcagcccca tcgagggcat gctgtaaaca
    48901 tttctaagtt gtgcgtgaca cgttgcgagc tggaagtcga tccttccacg tgtgagttga
    48961 tgcgtcacgt cagcgttcat cactctgcat tcacgatgtc ctcctgatgt ctgctgtcga
    49021 tttccgactg tacctcgtca cagatcgtca tcaaaccgcc gggcgtccgc tcggatcggt
    49081 cctggcacgc gccgttcgtg cgggggtgcg agcaattcaa ctgcgagagc gcgatctgcc
    49141 tgttcgcgac ctgcatgcac tggcaacgga acttcagcgg gagttgccgg atgcccgttt
    49201 gttcatcaat gatcgcgtcg atgtggctct ggccctgcgt accgtgggtg tacatttgcg
    49261 cgagagcagt ttgccggcgg gagtggcgcg atgtctgctg gggccttcgc aactgctggg
    49321 gacttcggtg cattccctcg acggtgtgat cgtggcggaa cagcaaggag cagacttcgt
    49381 tgtgttgggg ccaatctatg acactccgtc gaaacgcgta tacgggccgc cgcttggcat
    49441 gcgaattctc gaacaggctg cgcagaaggt acgtattcct atctttgcca tcggcggcat
    49501 cacagctgct cgcacgcgcg aggtgcgaca agcgggggca ttcggcgtag ccgtgttgtc
    49561 atcgatctta agcgcggtga acgtcgagca ggcgaccgaa gagttgcttg ctgcgatcca
    49621 gatggagtcg tgatgccgca cacgcacgcg tgatgttgaa cacgcatacg gtcgtggcgt
    49681 cgccgccgct cctggtgcag ttgaccaccc tataggcgga tgatagaatc cgaaacagtg
    49741 ctgatgatcg tcatggatta ggattttcat caatccggcg agtggggcga tggccgattc
    49801 aaaagggagt tcaggccgac tccggtcctt ccgtgattcc gtcaagcgcc tgactcggtc
    49861 actttctgac ggagatggag ccgtgacgca caagaacgac gaacatgccc gcgaagtgga
    49921 aaaacttcgc acccaaatcc agtcgatgga ggaggagatt cggcggctct accagtcacg
    49981 ctaccaactc gagcaaacga cgaagcaaaa cgaaaagctc gtcgccaccc tccaagaagc
    50041 caaatcacaa atcgaaacct tgcgggccga agtggagaag ctcacggctc cgccctcgac
    50101 ctacggcatt ttttccagtc tggataccga tggaaccgga aacgtgtatg tttccggtcg
    50161 caagatgaag gtgagccttc atccgtctat caaggcgaag gaactgcgta aagggcagga
    50221 agtcattctc aatgaagccc tcaacgtcat cgcggtgcgc ggttttgacg tacagggtga
    50281 agtggtgcgt ttgaaagatg tcctggaagg caaccgcgcg ctggtgacct tgcacttcga
    50341 cgaagagaag gtggccgagc tcggtgagcc gttgctgagt gagcggctca gcgtgggcga
    50401 tcacctcttg tatgatccgc gctcgggttg cgtcattgaa aagctgccga agtcggaagc
    50461 cgaggaactg gtgctggaag aggtcccgga tgtggactat gaacacatcg gcggacttca
    50521 gcgggaaatc gaacaggtac gcgacgcagt ggaactgcct ttcctgtacc cgcatatctt
    50581 ctccaactat aagttgagcg caccgaaagg ggtgttgctc tacggccctc caggctgcgg
    50641 gaaaaccctg atcgcgaaag ccgtggccag ctccattgcg aaaaagctgg ggcatttaaa
    50701 agaccggcag ctgcgcagct atttccttca cgtgaagggt cctgagctgc tgaataaata
    50761 tgtcggcgag tcggagcggc aggtacgcga agtgtttaag aaggccaaag aacgggctga
    50821 tgacgggcac cctgtcattg tattttttga cgaaatggac gccttgttcc gcacacgcgg
    50881 gaccggtatt tcgtcggaca tcgagtcgac catcgtgccg cagtttttgt ccgagatcga
    50941 tggcgtcgaa cgcctgacca atgtcatcgt catcggcgcc agtaatcggc aggacttaat
    51001 cgatccggcg gtgctgcgtg caggcaggtt ggatgtgaag gtgaaggttg gccggcccga
    51061 cgcgacggcg gcccgggata ttttctccaa atacgtgtcg acagatcttc ccttcgccga
    51121 ggaagacctg gcacggcatg gcggggatgc ccgagcactt gttgactccc tgatgaatct
    51181 caccgtcgat gccatgtatg ccaccaccga cgaaaacaaa ttcattgagg tcacctacgc
    51241 aaacggcgaa aaggaagtgc tctacttcaa ggactttgcc agcggcgccc tcattgaggg
    51301 catcgtctcg cgagccaaga aatttgccgt caaacgcgcc atcgctcaag aggggagcgg
    51361 cttgcgggcc gatgatctga ttcgagcgat tcgcgaagag ttcaaagagc acgaagactt
    51421 gccgaacacg acgaacccag acgattgggc gaaggtcgcc gggaaaaaag gcgagaaaat
    51481 cgtccatctt cggactatca gcggcgggcc gtcggaggca cgccagatcg aaaccgtcag
    51541 cacgggccac tacctgtagg cgcgcgatat cccatgaatg acactcattc gcacaatctg
    51601 tcccgtgtca tcggcacgga gacagaattt ggtattgcca gccgggatcc gaatgcggcg
    51661 gatcctgtag cgaactccat tcatgtgatc gggtactatc caaacttgcc cgcgccccag
    51721 gccgtgtggg actacgaaaa tgaaaacccc ttgctggatg cgcgcgggtt cgaggtcgat
    51781 ggggaacgcg agcgtccggg gccggactac aatcgacagc tcaataaggt cttggccaac
    51841 ggtggccggt tgtatgtcga cggcgcgcac ccggaatatt ccacgcctga atgtaccaat
    51901 gccagggagg ttgtggcctt tgagcgggtc ggggaacgca tcattgcgca ggctctggcc
    51961 ggaatcacgg aggcgcgcgg ccgcgatcaa ttcgttctgt ataaaaacaa ttcggatggc
    52021 aaaggcaaca gctacggcta tcacgaagac tatctcgtct cgcgcgccgt atccttcgat
    52081 cgaatcacgc aggtcctcac gccgtttctg gtgacgcgtc ccatttatgc cggctcaggc
    52141 aaggtcggcg ccgagaatca gaccccttcc gtcgattatc agatctcgca gcgggccgat
    52201 ttttttgaaa cgctcgtcga tctgaacacc atggtccggc gaccgatcat caatacgcga
    52261 gatgaaccgc attctgattc gaccaaatat cggcgtctcc atgtgattgt cggggatgcc
    52321 aatatggcgg agttgtctac gtatctcaaa gtcggtgccc tttcgatagt cctcgatctg
    52381 ctggaggctg gagccgatct tccccggata agcctggccg accctgtcaa tgccatcaag
    52441 caagtgtccc gggatacgca ggtgaaggag agcctcaagc tgaccgacgg aagcgcgaca
    52501 acggcgattg ccgtgcagcg ggcctacctc aaggcggcgc agagttacta tgcctgccac
    52561 gaactgaatc aggtcacgaa agacatcctg gtgcgttggg aggatgtgct tgatcgcctc
    52621 gaacgggatc cgcgtttgtt ggtgcgggag ttggactggg tggcgaagcg ctatctgatt
    52681 gagtcttaca tggaccgcaa gtcctgcgga tgggacgatc ctcgcgtgcg gttgatggat
    52741 ctgcaatatc atgatgtccg tccggaccgg ggattgtatt acaccctgga acgcagtcac
    52801 atgatcgagc gggttgtgct ggagcatgag attgtccgcg cggagacaaa tcctcccgtc
    52861 ggaacgcgag cctattttcg cggccagtgc gtcaagaaat acccgaatgc cgtctacggg
    52921 gtgagctgga cgtcggtgct ctttgatgtc gggcagaaca agatcaagcg gattccgtta
    52981 atggaccctc tgcgcggtac agaagcgctg acgggtgagc tcttcgccca tgcggaaacg
    53041 gcagctgcgc tgctcgaaaa actatcaacc tgactgcgac catcacatga atcgtatgcc
    53101 ctttcttcca caccacgacg gttcgagttt cttcgatttt ctcacccagc atcaccccga
    53161 attaagacca ggcgtacacg atctggcgat gccccgcgct acgcttcctc tagacctcgg
    53221 ccgtccaggc gccatcccgg tgccgcacgg aacgacggtg ctggcattga agtatcggga
    53281 tggggcgatt attgccggcg accggcgggc gacggagggg tttcagattg ccgaccggcg
    53341 gattgaaaaa gtgttccgca tcgatgagta ttccgccatg gctattgccg gtgcggccgg
    53401 cccctgtatt gaaatggcca agctttttca aaccgagctg gagcattacg aaaagctgga
    53461 gggtgtccag ctctcctgcg agggcaaggc caacaagctg ggacaaatgg tgaaggccaa
    53521 tctcccgatg gtgtttcagg ggttggtcgt gatgccgctc tatgtcgggt acgatgtgaa
    53581 gcgaaaagaa ggtcgtatct tcaaatatga cataacgggt gggcggtacg aagagtccga
    53641 tcaccattcc atcggctccg gcggtaaaga tgcacgcaat accatgcggg aacattaccg
    53701 gtcggggctt gatgaagagg ctgcgctccg tgtgggcctg ttggccttgt acaacgcggc
    53761 ggatgaagac gtgggaacgg gggggcctga tctcgtccgg ggaatctatc caacggccaa
    53821 ggtcgtcagc gatgccggta ttaccgatgt gccggaatca cgtgtgcgtg ccctatatga
    53881 agccatgatc gcagaacgaa ggagatcgta atcgatgccg ttgccctact acgtctcgcc
    53941 tgaacagatg atgcaggata aggcggagta tgccaaaaaa ggcatcgcca agggacgttc
    54001 gattatcgcc ttggagtatg tcgacggcat tgtgctggcg gccgacaatc ccagttcgtc
    54061 tctccacaag gtgtcggaag tgtatgatcg tatcgcattt gccggggccg gcaaatatag
    54121 cgaattcgag catctccgca aggcagggat acggcacgcc gatctgaccg gctatatgta
    54181 cagccgcgaa gatgtgagtg cccggactct ttccaacgcc tattcacaaa gcctggggac
    54241 ggccttcagc acggacgtga agccgctcga ggtggaaatc ctagtggtgc aggtcggggg
    54301 caacggccag gccaacgaaa tctttcgcat ctcgttcgac ggcagcatcg tggatgagaa
    54361 aagttttgcg gtcatcggcg ggcgatcaga agccgtgcag caatacctgc gcgaacatgc
    54421 gacgccgcag ccaccgacgc tcaaagatgg cctccggcgc tgtctctccg cccttgagca
    54481 ggtcgccact cagaagattc cttctgaaaa cctcgaggtc gcggtactgg acagaaaccg
    54541 tcaggggcga aagttccgac ggctcaccag cgccgatatc tcccatctgc ttgcctaacg
    54601 ttcatccctc aacatagtcc attgcggtat ggccggtcat tgtccggtaa tttccgatcg
    54661 cgcgtggacg acgaatgctc accggagtct gttgaagcca cccgcgtcag ggtgtatcct
    54721 gacaggagtc gcaccgaggg catccatctc catgcaacaa cgaattttcg gccttgaaaa
    54781 cgagtatggt ctgattttct ctcccaacgg gaagatctac cttccgatgg agaaagtcct
    54841 gggctacatc tttgaagggc tgattccgaa cagttggccg tcgaacgcgt ttctggtcaa
    54901 cggcgcgcgt ttctatcagg ataccggctg ccatcccgaa tactccacgc ctgaatgcga
    54961 caatattctg gacctggtga ttcacgataa ggccggcgag cggttgctgg aagcctgttt
    55021 accggcggcg gaggagcggt tacgggaaga ggggctctcc ggcgaaatct atatctttaa
    55081 gaacaatacc gactcgctcg ggaatacgta tgggtgccat gaaaattatc tcatgcgccg
    55141 ggatgtggat ttttggaagg tgaccgagca gctcatcccg ttttttgtga cccggcagat
    55201 ctattctggc gcgggcaagg tgttgaaggt ttccggcaag ccgcagtact tcatttctca
    55261 acgcgcgcag catatccacg aaaagacgtc ctcctcgacg acctcttcac gcagtatcat
    55321 caatacccgc gatgagcccc atgccgatgc ggagaaatac cgccggctcc acatcatcgt
    55381 gggcgattcc aacatgtcgg aatacgccac ctatctgaag gtcggcactg ccacgctggt
    55441 cttatcgatg atcgaatcgg gtttctccgt gacgggcatg gaactcgagg atcccgtcaa
    55501 agccatccgc gaaatctctc gcgatcctac gctgaacaag aaggtgaagc tggatgacgg
    55561 gcgacagatg accgcgatcg aaattcagcg cgtctatgtc aagcgagcca cagagtttct
    55621 ggccgcgcag gatcacgatc cggttctgga cgacgtgctg gacaaatgga tctccgtgct
    55681 ggatcggctg gaagacgacc cgatgcagct cgtgcatgag gtcgattggg tgatgaaaaa
    55741 acatctgatc cagtcgtata cggacaaaaa ggattgcggg tgggatgatc ccagagtgtt
    55801 cctgctggat ttgcaatttc atgacgtgaa acggacacgt gggctgtatt atttaatgga
    55861 gaatcgtggc atggcagcgc gggtcgtgga ggaagaggcg gtacaacgag ccatgtcggt
    55921 cccgccacag actaccaggg cgaaagtccg cggtgacttc atccggtttg cacgcgccaa
    55981 gaatcggtcg tatacggtcg attggaccta tctgaaactg aacgggtatt gggaagagac
    56041 gattctctgt atggacccgt tcagcgcagt caatcggcgc gttgaagaat tattgtcgca
    56101 ggtctccggt gcgcgattgt accgatgaga cgggttggtg gagtgaatcg agcccacacc
    56161 atgtcgttcc tcgatcgctt tctcatcatc tcggtcgtgc tgctcgccag cgtgtttcct
    56221 gttgagctct tcccgaacac ggggcctgtt cctcgcggcg gagacgggca attcagcggc
    56281 aagcagggtc aggtggtcgt ggtgaccgtc ccggaactca aggaagccac cagcgtcaaa
    56341 ggaaagttcc tcggtcgcac tgtaaccctg ttcccgaatc ccaccgccgg aggcacgggc
    56401 tacatcggat tgctcggtat cgatctgcaa gatgaaccgg gaccgcatga gctgactatc
    56461 gatgcgcaac taggcgagca aaccagacat ttttcgtatc aggtgcttgt cgtaaaggag
    56521 aagtttgccg tcgagcatct gaaactgccg aaagataaag tcgatctcga tgagaaagcg
    56581 accgcgcgct ggaaggctga gcaagagcag gttcgaaagg ccttagcgga agagtctgcc
    56641 atgcgactct ggcaggcggg gtttatcgag cccgttcacg gtaaacggac cggcattttt
    56701 ggcagtgtcc ggattatgaa tgggcaaccc aggaatccac acaacggaga agatatcggc
    56761 gccccgatgg ggaccgacgt gatggccagc aatgacgggg ttgtgcggct cgtcgtcgat
    56821 catatttttt cggggcgagg catctttgtc gatcatggcc tcggtcttta ctcgatgtac
    56881 tttcacttgt cggaagcgct ggtcaacgaa ggggatctgg taaaagccgg tcaagtgatc
    56941 gggaaggtgg gcgccacagg gcgggcgacc ggtccgcatc tccactgggg gatgaaagtc
    57001 aacggcgctc gggtgaaccc ctacgcgctc ctcgaattgc cctttccgca gaatcccgcc
    57061 gcggaccgcc cggtactggc ggcgccagcg gtccccgctc aggaagaatt agctcccaca
    57121 gcagtcggtg gtgacggccg gtagtccgtc cctccagtac gcccctcgtc gacttcgtgg
    57181 ctctgataac ccttcaggtt gagtgcgacg acgtatccct gcagcttcct tgtcgagtct
    57241 gtgattccag cgctgaggcc acggtcttgg tcagcgactc gggcgtatac ggtttcggca
    57301 aaaaggccac ctgggcatcg aatgttttga ggagtgtttc atcgcgccct gaatagccgg
    57361 acgtgaggat gactttgatg tccggttgga gggtttgcag ttcgtgagcc agctgggcgc
    57421 cgcccatgcc cggcatcacc atatctgtca ccagtagcgc aatgtggcgt ccctgccggc
    57481 gcaccatttc cagcgcttcc tctccggagc gggcggccag gacatgatag tgctgggcaa
    57541 caagcacggt atgggccaga cctctcacca tgtcgttgtc ttccaccagt agaatggttt
    57601 ccgactgttc gctcgtgacc ttgggctgcg tcaccgcgcg aggagcgccg gtgtcttcct
    57661 ccaggcgcgg caggtaaatc gtgaagctgg tgccttttcc cacctcgctc gtgatcccca
    57721 cggtgccgct gctttgtcga acaatcccgt agaccgtcga cagtccgagc cccgtcccct
    57781 tgcccaattc cttcgtggta aaaaacggtt cgaagacatg ggccaatgtt tcggcgctca
    57841 ttccacaccc cgtatcacga acggacaggg ttacataagg cccaggagga agaggatcag
    57901 gccagaatgg atcggaatgg gagatcatca cttccccggt ttccaattcc agccggccgc
    57961 cgtggggcat ggcatcccgg gcattgacga ccagattcat cacgacttgt tcgatctgcc
    58021 caggatcggc tttgattcgt cccaacgtcg ggtccagggt caggacgaga tgaatgtctt
    58081 cgccgatgac ccgtttcatg agttcgacga tatcgctgac gcgctcatta aggttcaggg
    58141 actgccgttc gacgacctga tggcgtgtga aggccagcaa ttggcgcgtg agtccggtag
    58201 ccttgttgcc ggcttctctg atttgcgcca tgcctcgctg tgcccgggac gtcaggcccg
    58261 gttcgtccat caacagttcg gcccaactat tgatgatggt gaggaggttg ttgaagtcgt
    58321 gtgccacgcc tcccgccatc cgtcccaggg cttccatttt ctgcgcctgg cgcaactgtc
    58381 gctccagatc tttccggttg agaaattggc tgatcatcgc gcccagctcg gcaattcgct
    58441 ccatgcggga cacggcaggg tgcaggactt cgaccgtaaa aaactccatg atgcccagga
    58501 tctctttgcc ggtgtggatc ggaaaggcga tcgctccatg gaggtccgcc tctcgcgcgg
    58561 catcatgcgc ggggaagtcg gcctcattca caatatccgg actgaatgcc ggggcgtccg
    58621 ttttccatgc ccgtccagcc attcccatgt cctgtcttag gaacaaggtg cgataggcct
    58681 gggcgaagtg ctcggtctgt tgccctgagg gatgccagag tgcattgcag cgtagaaccg
    58741 agtgttgagt atcgacaagc cacagcgcac ccaatgtcca gccctgaagt tcgcacatcg
    58801 cgcgcagaat ttttggcacg gcctcattca acgacacaga ttcttccagc gcgaggccca
    58861 cggtgagttg aacggcatgc atggtttctg cctgccggcg gtcggaaatg tcggtttttg
    58921 ccccgatcat ccggtagggg gtgccggcat agttccggag cacatagcca tggtcgatga
    58981 catacgcata ggtgccatct gctctgcgaa aacgatattc cgccgtccac aagtttttgt
    59041 cggactccag tgtatggctg aggcccgcaa gaatcgattg gcgatcctcc ggatggattt
    59101 ggtctgccca cgcaatccgt cccgcttccc gcgccttcgc ccctgagccg tagacggttt
    59161 gnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    59221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ncccacgcaa tccgtcccgc
    59281 ttcccgcgcc ttcgcccctg agccgtagac ggtttgatag gcatcgttga accaggtctc
    59341 cccggacgta atgtcccaat cccagatgcc gtctctggtg gcaagacagg tgagatgaaa
    59401 tcgctcttcg cttttccgca acgcctgctc tacgcgatgt cgccccatgg cataccggat
    59461 ggcgcgtttc agcccatcac ccgttaatcg ccctttaacc aaataatcct gcgccccatg
    59521 cagaagagat ttctccgcca cgaggtcatt gtcgagtccc gtcagtacaa tcacggccgc
    59581 ttcatgagct tgggcccgca cgcggacaag cgtgtccatt ccctggctgt ccggtagcga
    59641 cagatcgacc aacacggcgt ccggagagcc ttcggcaagt ttcagcaggc cggcttccag
    59701 acggtccgcc caggtgagca ggacatcctg cggtgagtgc tcgcagagtg cctcgcgaat
    59761 caatgccgcg tcatcttcat tgtcttcgat cagcaacacc tgcatgtgtt acctcttgag
    59821 cgtcggaacc ttggagacga gcgtccaata gagttcgaat tctttgacga ccgcgatgaa
    59881 gcgggtgaag gtgacgggct tgcgaatata ggagcaggcg cctttctcga acgaacgcac
    59941 aatatcctct tcccgctcgc tgaccgtcag gatgacgacg gggatggcac gaaatcgcgg
    60001 gtcggatttg atttcctcca acacctcgag ccccgtcttt ttcggcatat tgatatcgag
    60061 gagcaccatg ccggggagcg gacattggct gaacgagcct tcaccgcgga ggtaggccat
    60121 cgcctcagcc ccatcccgga cgacggccac ccggttggtc atgttgacgg tttcgaacgc
    60181 ctcgcggatg aggagaatgt catcttcatt gtcttcagcg atcagaatat cgaacggcct
    60241 catcgtcata gtcctacctc tttcacaacc tgccggttga tcccgaatgt gataaaaaag
    60301 tccgatcctc ctccctcacg gggtaagacc caggcgcggc ctccatgccg ctccgccact
    60361 tgccggacga tggccagacc ggctccggtt ccttcgattt cccgtcccac cgctcgccgg
    60421 aacaactcaa agatgcgctc acgctggtcg gacggaaccc ccggtccgcg gtcgcgtatg
    60481 accaggccgg aacattccgt cccctcagca tcaatctcgg tatggggagc aatctcgata
    60541 tccggaggtc tcccgtcagc gacaaacttc aaggcattcg ccaccagatt gtagatgccc
    60601 tggacggccc aggtcgtatt gacccggagc cgcggcaacg gcgtgcacac cgtgatcgtg
    60661 gccccgctct ctttgatgcg gctttccagc cgtcgtaaca cctcttggac gagctgatgc
    60721 gcgtcgatct cgtcgaccgg tggttccatg cgctgggcgc gggagaggtc caaaatgtcg
    60781 gtgagcaatt ggtcgagccg ctgtgtggcg cgtacgatgc ggcgaagaaa atcctgtcct
    60841 ttctcatcaa gccggctcgc atagcgttcc tgcagcagaa ccgaaaaact ttcaatcgcg
    60901 cgcagcggtt ccttcagatc gtgcgaggtc acatagagca gggtctcgag atccttattt
    60961 ttcttcagga tcatcaattc ggcttggcgc cgttcggtaa tgtcccggtt cgtttcgagg
    61021 accaggctgc gaccccctgt tttcatcaat ccccagcggc tttccacgag cacctcccgc
    61081 ccgtctttgg tgcggtgatg taactcgccg gtccaggctc cggtcgcttc caattcagca
    61141 caaatggtgt cgaaagggca tggataagta cttttcagca gtgtgtggct gcttcgtccg
    61201 atcgcttccg cacgggtgta gccgtacaat tgttcgcatc cccgattcca atccaggatg
    61261 ccccgctcaa aatcccaggt aaaaatcggg tcataggaca gttcaatgag tcggcgctgt
    61321 tgactcaaga cttcctcggc acgtttgcgt tccgtgatat cccgggcgat cgtcgacacc
    61381 gccgtcacct ctccgttggc atcgactatg ggcgacacgg tcaaggacac ctggatgggg
    61441 tggccgtctt tatggagacg cacgctctcg aattgttgga tgcggattcc cgctgtgatc
    61501 tgctcgatga ggatggcttc ctccgcccgg cgctctggcg ggagaatccg ggagaccggc
    61561 tggccgataa tctcttcgct aggatagccg aacatcaact ccgcgctttt gttccaggac
    61621 aagatccgtc catccaagcc cttgctcaga acggcatcgg atgatgattc cacgatggaa
    61681 gccagtctgg cctggatttc ctgcgcttgt ttgcgatcgt ggatgtcggt gtaggtcccc
    61741 acccatttta gcaggtggcc atcgtgatct cggatgggcg tcgcatgcgc atggaaccag
    61801 cggtagatgc catccgcccg cttgaagcgc agttccgtat cgaggggctg aatatgagcc
    61861 acggagtggt gccattgctc ggtgattctc gggcggtctt caggatgaac gtgctggaga
    61921 catccggtgc tgaagggctc gtctgcagat cgtcccgtat aatttgccca tcgagggctg
    61981 agatagtcgc aggtgccgtc agggaggcag gtccagatcg gcagcggcag ggattcgaca
    62041 agttcgcgaa accgggtttc gctcgcaatc agtgcctgat gcatctgttt gctttgtgcc
    62101 agctcctgtt ccaaacggct gttggcttcc tgaagcgcag ccgtgcgttc ttcgaccaag
    62161 gcctcgagag actgatgact cagacgcagg gcctggtcag cgcgtttgcg ttccgtaata
    62221 tcaatcagcg tggagcggct tgacacgaac cgtccgtcag agtcggtcac ggccgtggca
    62281 ctgagcagga cggagaatgt cgacccgttt tttcgaatca gctcaaactc caaatcgttg
    62341 acgtagccat ccttgataaa ttgcggaaat cgctccttga acaggccgac acccgccggc
    62401 gtcatcacgt ccgtaaatcg gatttttcca atcagttctg atttcgtata gcccaaccag
    62461 tccacttcgg tccggtttat agcaacaatg agaccattcg catcgagcga atggtagccg
    62521 cagggcgcac ggtcatagag gtcctgtacc tcttcagcag tcttcctcag caactgcgat
    62581 cggtccaaca gggccttgtg ctctgcagcc attgtggtgg acttcagcag ttcggaggtc
    62641 aagcgctttt gtcgatccac gacataggcg atgaggggaa agagaacaat gctgaatgaa
    62701 cggctgacct gtggcagcca ggtaggcact cccggcacat cagcagacaa cacatacgcc
    62761 agatacgtga gccccgcgca gccgacggcg acggcgtgag aactccaggg atgaggggtc
    62821 caggtggtga gaacaatggg aagggtatac agcacccacc cgggaatgcc ccgtggggtg
    62881 aggcagtcca acacaaacat ggcgccgcac aatgcagcaa tgaacgcgcc tatgcccagt
    62941 tcgcgaatgc gaggcgtcag cttgtcggtc attagcccgt agagaccatt gctggtcatg
    63001 gggctcctgc tttgtggcgc accgtgccgt cgctcagata gacagagagc gatagatcaa
    63061 ttgtctcgtc agtatgagta agagaagtaa aattcaacag atgcgatatg ccctagtgcg
    63121 attcctaggt atgagagtaa gggccggaat ccgttttgcc gggtgtgcat tgggcggcgg
    63181 cagcaaggaa cgacgggtca gaaattcgtc tcgatgctgg acggggtctt gttcaagacg
    63241 gtcgcggcgg ctctggagag ggcggcatca tgggcatgat cgagcgcata gatgcgaaac
    63301 tggaccagcc gggttggaag aaggtcgaga aactcctcta acggctcggt ggagagtcct
    63361 ttggtgccgg gatcgtaaac gagcagagga atcccgcgcg tatctttcgg gtccggtcgt
    63421 gggtccaggg gggccatatc aacgcggaac ggcaggtctc gtaacttcgc cggcaacgcg
    63481 ttctgaatct gctgctgaaa ttgctcgtgg ctgggaaagt ccatgccccg ctcgatgccc
    63541 ttttctttca gtaccgtgct gtacgccatt ttccatttca cgtcgcggct gaggatatgc
    63601 gcccattcct ggtgcaagcg acgcaggctg ctctgcccgg cttttttcca tcgtcgcacg
    63661 tcttccagta acgaccagtc ggtgagcgtc aggtactcgt ccatatgttt ggctggattc
    63721 gaggggaaca acagcttcat ggtatcgccg aagatatcgc ggagatgaat gtcgatagcc
    63781 ctggtcgtcc ggtgataata cacgttcgag tataagtaca ttctcgtgtt caaaaacatg
    63841 tgcagggccg gcaggccggt tttatggatc gtgaagccct tctcggtcac gatggtgtaa
    63901 tgaatcaatc gcgtgaggtc gaccggtccg accgccacgc cgcacatgta ggcgtcgcgc
    63961 agcacatagt ccaaattgtc ggcggtataa cttcctgaaa taaccggttg gagcacattg
    64021 atccagcggg gaatctttga attgtccttt cccttctcct tcaggatgac atgcgcgatg
    64081 tgatccggat tgagttcctc gccgcgatcg aacggccccg acgggctacg tcgaatcttt
    64141 ttgatgagcg gtccgagatg ctcccggacg atgatctgtc cgagcttttc atgcgaaagg
    64201 ccgaagccgt gcagatagtt gtcgtcgaag aaatggcaga acgggccatg tccgatgtcg
    64261 tggacgagcg cggtgatgcg caggaattct tcgacgaagg cggcagaggg aaggtcgggc
    64321 acggcgttgc gcaaaaaggg atacaggtgt cgcgcgaatc gtccggccac atgcatggtg
    64381 cccaaagaat gcacgaaccg cgtatgctcc gccgatggat acacccagcg ggcgctctgg
    64441 agctgataaa tgtaacgcag ccgttgaacc cagggagaat caatcaggtc tttttcagtt
    64501 cgttctgatg ggtctggtgt cgcatagggc acggtgaacg acacgtattc gtgaatcgga
    64561 tcggcgatga gggccgatcc gtcgtaggga gccggtggag tggaggatgg gagtttcata
    64621 gggtcatgac cgacgaagga tcttagccca gccctgaggg cgggggcaaa tgggtggcgc
    64681 gttcaaccgc tctcgcacgg cgatatcttg tgagcagcac ataggcgatg gggtacgcca
    64741 gcaggctgcc ggcgatgctc aggaccattc ccccgagtac aaacggccag gcatgtggcg
    64801 ctacctgatg gtacaggccg gtgaatgaca agtcgctcca gtcgaacgta ggaaattctc
    64861 gcatgccgag cagggtcgcg ccggtccagt acgtcgcgcc gaggatcgga atgagggtcc
    64921 agggattatt gaggaatgct ccggcgagca gcgcgacgac gttccagccg aacagccagg
    64981 cgcacaggcc caccatgatc atatgcaggc catacgccgg cgaaaagccg atgaagacgc
    65041 cgacggcaaa ggccagcgcg gtccgatgcg gcgtttcatc gagatgcaga atttggcgaa
    65101 acagcgatcg tacgtcggcc ataagtcgtc aggtatcggg ctcgttacgt cggcctgcga
    65161 aaatgttcgt agctggtgag tggcaggggt cgtgtggcgc ccgcgtccgt cctcagtcgt
    65221 agaccggccg ccttcggcgt gattgaaccg atacaggtca tacgaaatcc ggtcttctta
    65281 accagtcgtt caaaccggag ctgttgtccg cgagggacgg taaacagcaa ttcataatcc
    65341 tcgcctccct gaagcgcgat ctcaacaggg tcgaggccgc gagccatcgc atacgctcga
    65401 caggctcgcg aaagcggcag tgaaccggcg atgatttcgg caccgacccc gctttcctcg
    65461 cagatatgac gaaggtcacc agtcaggccg tctgagagat cgatggcggc ccccgcgagc
    65521 ccatgtcgaa ccagccacag tccctccgcg atgcgagccg acggacggtg atgccggccc
    65581 agcagaaacc gagcatctgt cggtcgcagt ttcggccgcc gccgcgatgt caggagatca
    65641 aggccggcac gggagtctcc cagtgttccg gtgacataaa tcagatcgcc gatgcgtgcg
    65701 ctgctacgta gtagcgcctg gcgtggtttc acgacaccgg tgagcgtgat gttgagaaac
    65761 agtcctgtct tggaggcaga cgtgtcaccg ccgacgaggc gcacccgata gggagcatcg
    65821 gcctccgtca tgccgcggta gagttgttga atctgcgtcg tcgagcaggc ccgcgggatc
    65881 gcaattgaga ccagcataaa ccgtggcgtg ccgcccattg cggcgatatc gctgagattg
    65941 gcgatggcgg cgcggtagcc gatatcccgg aaggaggagg tcgtaggatc aaaatgcacc
    66001 ccctccgcca ggagatccgt ggtgatgagg gtccattcag ttgacgatgt tttgaggatc
    66061 gcggtgtcgt cgccgatccc tttgaagact tgcggatccg gttgggcagc ctgagcccgc
    66121 agttttcgga tcaggccgaa ctcactctgc acggtgctgg cccggcgggt tcggcctggc
    66181 ggcattactc caccttcttc caggccgatt gccgtaccac atattcaggg ctggcagcag
    66241 cagtcctcat gcaacgcggg ttacagagac agtgagcggg tggtccctgt caacgcacgc
    66301 ctgcggcgtg gcgaggcggc tgcttttcgc ttggaggccg tcacgggcga gggtttcttc
    66361 agcggcgttt tcggtgcccc agccgtagct ttacgcgagg gagcccgccg cagggctgcc
    66421 ttgatgacat cgtccaccgt atcgacgaag atcaattcaa tccctttcag gatatgtttg
    66481 gggatctcct ccaagtcctt cttgttgcgt ttgggcaggg caacggtgga aagtttggcc
    66541 cgtttggctg cgaggatttt ttctttcaag cctccgatcg gcaacacccg cccgcggagc
    66601 gtaatttctc cggtcatggc aagatcgcgc cgcacgggga tttgcgccag ggcggacgcg
    66661 atggccgtgg ccatcgtgat tccggcagag ggaccgtctt tcggtgtcgc gccggccggc
    66721 acgtggatat ggatgtcgtt tttcgcgaaa aggtcggggc tgatgccaag cgtcttctcg
    66781 cgcgaccgca cgtaactgag tgcagcttgg gccgactcct tcatgacatc gccgagatgg
    66841 ccggtcagcg tgagctgacc cttgcccttc atgacggtcg cttcgatgta gaggacatct
    66901 ccgccgctct cggtccaggc cagaccggtg gcgacgccga tttcgtcctt ctcaagttcc
    66961 gcctcgggaa tgaatttcgc cacgcccaaa tacttgttca ggttggtctg atcgatggca
    67021 tggcattcag ccttgccttc ggccaccttc ttggccacct tccgcatgag gttggccact
    67081 tcacgctcca gattgcggac gccggcctcg cgcgtgtaat gggagatgac atggcgaatc
    67141 gccgtctctg aaacgcggat atgtttctcg gtaatcccat gctcgttcat ctggcgagga
    67201 atgaggtatt tctgcgcaat cccgagcttt tcctcttccg tgtatccggg aatatcgatg
    67261 acttccatac gatcccggag agcaggaaga atcggatcca ttaagttggc cgtcgtgacg
    67321 aacatgactt ccgtcaagtc aaacggcacg ccgagatagt ggtcggtgaa cgtgctgttc
    67381 tgctcagggt ccagcacttc caggagcgcc gccgaggggt cgccacgaaa atccatgccg
    67441 accttatcga cttcgtcgag catgaagacc gggttgttcg tgcccgcttg tttcatgcct
    67501 tgaatgatcc gtcccggcag cgcgccgacg taggtccggc gatggccgcg gatttcggct
    67561 tcgtcccgca ctcctcccag gctgattctg acgaattcgc ggcccagcgc ccgcgcgatc
    67621 gattttccca gcgatgtttt gccgaccccg ggagggccca cgaagcacag aatcggcccc
    67681 ttcatttttt ctttcagctt gcgcacggcc agatactcga cgatgcgctc cttcaccttt
    67741 tccagatcgt agtggtcctc gttcaggacc ttcatcgcag ccttcaggtc gagattgtcc
    67801 ttgctctttt tattccaggg cagctcgacc atccattcca gataggtgcg gactgtggcc
    67861 gattcggccg tgtccggatg cattttctcc agccgcttga gctgcttttc agtctccttg
    67921 agcaccttct cgggcatctt ggcgtctttg atgcgcttgc ggaattcggc cacttcctcc
    67981 gcccgctcgt ccaattcgcc cagttctttt tggatggctt tcagctgctc gcgcaggaaa
    68041 tattcccgct gggtcttgtc catctcgcct ttggcctgcg cctgaatttt ctgctgcatc
    68101 gagaggacat cgatttcttt cgcgaggatt tcgctgatct gccgcagccg ctggatcggg
    68161 tccacaattt ccagcaccgc ctgggtgatg tcgactttca gccccaggtt ggaggccacc
    68221 atatcggcga ggcgtcccgg atcctccagg ttttcgatca cgaccatcac gtccggaatc
    68281 aggaccttgc cgaggctgac gatcttttcg atctgctcct tgacggtgcg cataaccgcc
    68341 tcggtctcca aggtggagcc gggctgcttc gtctcgacaa gtttttcaat tttgacggag
    68401 tagtagggat cgttctggat atattgttcg atccgtccct tggcgaggcc ttgcaccaga
    68461 atcttgatcc gctcatcggg cagcttgagc atccgcatga tgatgcccac tgttcccacc
    68521 gaatgaatgt cctccggttg cgggttttcc acatccaggg atttttgtgt cgccaggaac
    68581 agcatccggt tccccgccag cgccgcctcg atcgccttga tcgacatttc gcggccgacg
    68641 aacaggggga gcaccatgta gggaaagacg acgatgtctc ggacggggag gagtggaagc
    68701 tgatcgggcg gttcgaggtt ctgattgctc gaaaaatctt gttctactgc ttcagccatg
    68761 aggctccagt ctgctggtgt atggtctcag tgacgatgtc gtgcgagggc acggttcggg
    68821 tgacggtgat ccatcatgcc cggggctagg ttgtcgcgcg ccctcgaccc gggccgcggc
    68881 gacggacgtc ggcggtagtc ggtcggagtc gctgctgcag aaaatcgccg aatgcaggtc
    68941 ccaaggacgg gttcttcagg gccaattcca ccgtggcgat gagaaatccg agtttgtcgc
    69001 cggcatcatg ccgctgtcct tcgacttcgt gcgcgaacat cggcgtgttc ttcacgagtt
    69061 gccgcagggc atccgtcaat tggatttctc cgttcttgcc cggaggggtc ttgcggagga
    69121 tcgggaaaat ttcaggtggc agcacatacc gtccgatgac ggccagattc gacggggcat
    69181 cggcgggcgc aggtttttca acgaggtctt ccacccggtg cagaccgctg cgcaccttgc
    69241 gggccgagat gatgccgtac cggctgactt cctgctgcgg cacttcctgc acgccgagca
    69301 cggcgccttt gcgctgcttg tagatatgga tcaattgcgc gagaccggga accgccgcat
    69361 cgatgatctc gtcacccagg atgacggcga acggttcatc gccgatcaga tgctgcgcgc
    69421 acaagacggc atgacccagc cccatggctt ccggctggcg gacgtagcag aagttcgcca
    69481 gattggaaat gtgccgcatc tggttgagga cctgcccttt gccgctgccc ttgagatttt
    69541 cttcgagttc aagggaacga tcgaagtgat cttcgatcgc gcgcttgcct cgccccgtga
    69601 tcacgatgat gtcttcgatg cccgacgcga ccgcttcttc gacgacgtac tgaatcagcg
    69661 gtttgtcgac cagcggcagc atctctttcg gggaggcttt agtggcggga aggaagcgtg
    69721 tgcccagtcc ggcagcggga ataatcgctt tacgtacgtc tgttcttgtc ataacggcga
    69781 tagtatgtga tggggtacat gaagtcaaga tttcgtcggc tcttttcgat cgctgccggc
    69841 gcgccgccgc gcagggaaac tcctttacat tgaaaaatgt gctcaatata atccgagagt
    69901 ttttctgcag acgtgcggtg gtgctgcaac gaacgcggcg catcggtgac tcttatgacg
    69961 acagttcgcg tcccttcgcc cgaccatcgg ttcgcggcaa gacacgcggc atggcatgtg
    70021 acgatctctc atcctgaagg tcgaacgaac cagtgcttgc tctcccagac ggtacggaag
    70081 gattacggtg accaagtcgg gaggcaggcg gtgggtgccg attctcgtcc ttgtcctggc
    70141 ggcgctgttc gtgatcggcg aagcagggtg ggtgcgggcc caagtcagtg ccccgctggt
    70201 caattccgtc accatccgtg gtcagaaacg cattgaactg caggcgatcc aggggcgtct
    70261 caccctcaag gccaacgatc ggtttactcc tgacgcgctc cgggaacagg tcaagattct
    70321 ctacggaacc ggctacttcg aggatgtgca ggtggaaacg gagacggccg atggcggcgt
    70381 cgccgtcggt ttcatcgtcc gtgagaaacc cttcattacc gagattgtgt tcgatggcaa
    70441 cgaggaattg agcgacgaca agctcaagga aaaaatcacg atcaaaagcc aaacctttct
    70501 cgaccagcag caggcgaaag agagcgcaga gaagatccgc ctcgcgtacc aggaagacgg
    70561 cttctacaat tgccaggtca ttccggtgat tcaagccgtc gatgaggacc gcaaacggct
    70621 gacctatttc atcaaggaag gcaccaaagc gaaagtccga cggatcaatt tcgaaggcat
    70681 gcgcgcggtg accaaagaag aagtctttaa agtgacagcc acccgcgagt ggattccctg
    70741 gtacggtctg atcacgcaac tgaagctgcc gtcgctgctg tcggatgccg gtgtgctgaa
    70801 gcgcgaggag ttgggcaacg atatcgaacg tatccgcgaa gtctatttga acaagggcta
    70861 cttgaacgtg cagatcagcc agccgacgct ggaactgagc gacgacaaga agtggttcga
    70921 aatcagctat tcggtcgtcg aaggggagcc gttcatcgtg caggaagtcg ggttccgcgg
    70981 caacacggtc ttcgaggatc atgaattgcg tgaagggttg ggaatccgcc cgggcgaaat
    71041 ctttcaacgg gccaagatcc gcggcgaaat cacgcgcatt accgatctct atggcgcgaa
    71101 ggggtatgtc tttgccgatg tcgtgcccaa cgtgacgccg gacaacaatg cgcgcaccgc
    71161 gacgatcacc ctcaacgtca aagagggcga gatgatgcgg atccgcgaga tccatgtcac
    71221 cggcaacgac aaaacgcgcg acaatgtcgt acgccgggaa ctgcgcctgg atgagcagga
    71281 cgtcatcgat acgctggcct tgaaacgcag ctttcagcga ttgaacaacc tcaacttttt
    71341 cgaaacggtg gaaattcttc ctcagcaggt tgatgtcgac aaggtcgatc tcaatgtgaa
    71401 ggtcaaagaa aaacctaccg gccagttcag catcggcggc ggattcagca ctctcgataa
    71461 actcgtcgcg attgcggaca tcacggaagg caaccttggt gggaacggat ggttgggtcg
    71521 tatccgcggg caattgggtc agcagcggtc cttgggactc gtgacgttcc ggaatcccta
    71581 cgtgaacgat tcgtacaatg cccttcagct cgatatttac cggtccatga ccaactatat
    71641 ttcctacttc gagtccaagt ccggagccag cgccacgtgg agccgatggc tgtcggagta
    71701 tgtcaatgga agcatcagtc tcttcggcga gcagctcaag tacagcgatc cgcaagaagg
    71761 gttgtgcccg gatctgattc cgctgatctg ccgccagctc gggacgcaat cgtccaccgg
    71821 gttccgtacg tcgttgttcc gtgacacgcg tgactattat ctcgatcctc gcaccggatg
    71881 gcgcttgagc gtcggtgccg actacggaac acccgcgctc ggaggatcga accatttcta
    71941 taaagtgtat ttcgacgtca tcaagtacac cccgctggtc tatgacacgc ggttctcggt
    72001 acatgtccga tacgggcaga cagaggggat cgggggccgg cccattcccc tcaccgagcg
    72061 gttcttcgtc ggaggcatca atacgatgcg cggattcgtg ttcggccgtg caggtcccgt
    72121 gacgccatcg ggctcgctcc tgggttccgc caaggagctc atttttaaca acgactttat
    72181 ctttacgatt tcgtccgagg cgaagttgaa cggggtgttc ttcttcgatt acggaaacgg
    72241 attcgacgac aacgagccgg tgcagtttaa taagttgcgg agtgcggcgg gatttgaagc
    72301 caggtggatt tctccgttcg ggcccttgcg cgcggcgtac ggaatcaacc tcgatccccg
    72361 gccgaccgag cgtatgggcg tctttgagtt tacgatcgga tcgttgttct gatgcaggtt
    72421 ctgtggcgcg ggtgtaggaa aggaattgag cgcatgcgtg gactggtagg ctggaaaagc
    72481 gtgcgaggag ccggatggaa tggactctgc ctggcgcttc tggccgtcac gctgctggtc
    72541 ggcggatgcc gctcgaatcc ctcgacggta ccgacgtcca cacgcatcgg tgtggtggat
    72601 cctcagcgta ttctgggcga aaccaacgcc gggaaacgag cgaaggacat gttggcctcc
    72661 ttcgccaaga atcggcaggc gctgatcgag ctcgaagaaa aagaacttcg ccggatggaa
    72721 gaagacttcg tcaagcaagg cagcgtgctc agcgcgactg ccaaacgtga acgggaagag
    72781 cagttccggc gccggatggc tgaatatcag cagaaagtca ctgatctgaa ccgcgaagtg
    72841 caggacaagc agaaggaagt cttggacgga ttccgggata agatcgaatc cctgtcggcc
    72901 aaggtagcca agcgattgga actgcaggct atcttcgacc gcgggcgcgg aggaccgacc
    72961 ctttattttg atgaggcggt ggatgtgtcg tcgcagttga tcgaggagtt caacaaaacg
    73021 tatccatgag agggaatcca tgaacgtacg taactggatg gcggccggtg ttctacaagt
    73081 ccttgtggcc tggggggcgc agccggtctt ggctgccgat cacctcaagg tggccatgat
    73141 ggatcagcaa caggtcatcg agcgcagcgt cgccgggaaa cgcgccttag aggaactgaa
    73201 gagttattcc acgacgcgcc agaagatcat cgattccgac gaccaggaat tgaaggatct
    73261 ggaaaagggc atgcaggacg cctccatgtc ggaggatgcg cgcaaggaaa agcaagagca
    73321 cttcaggacg aaactggagg cctaccagcg ccgcattcag gacttcaatc gcgaggtgca
    73381 ggaaaagcag cgcggcatgg tggcggagta tgcccagaag attcaagccg ctgcagcggc
    73441 ggtcgcgcag aaggaaggct atacggctgt cctggacaag ggcagcgagt cgacggtgaa
    73501 gatcgtgatc tacagtcacc cgtcggtcga tctgacggaa cagatcatca aggaattcga
    73561 tcggcagaac aagtaaccgt cgatcgtaat cgtctacgca acacaggagg cggggctgat
    73621 gtcagtgatg gacaacgttg agattcaatc gatccttccc caccggtatc cgtttttgtt
    73681 ggtcgaccgc attcgcgaac tcgatcctga tcgccggatt gtgggtatca aaaatgtcac
    73741 gatcaatgag ccgttttttc aggggcactt cccggggcgt ccggtcatgc cgggcgtgct
    73801 gatcctcgaa gcgttagccc aggtcggcgg cgtgcttgcg ttcaaatcgc tcggtgcagt
    73861 ggggcgaccg gtcgtgtatt tgaccggaat cgacggggcg aagttccgca agcctgtcgt
    73921 gcccggcgat attctgcgat tggaggtcga cgtgctcaag aaacgtgctc cattctggaa
    73981 gatgcagggc aaagcctttg tcgataccga gttggtctgc gaagcggaag tcacggccat
    74041 ggtgatggac gaaaaggcgg ccggcgagaa ggccgcgggg tagagacgca gtttccccgc
    74101 cggtcggtgg ggagtagagg gaaccacagg ctgtgtacac gctgttcagc gagattatgc
    74161 gcatgctgac cggtgtttcg gcggcctgcc agagggcgag gaggtgtgag tgaagattca
    74221 tccgaccgcg gtgatccatc cgaaagcggt gctcgcagat gacgtggaag tcggggcgta
    74281 ttccgtcgtc ggtgaacacg tcacgatcgg tgccggtacg cgtgtgttgt ctcatgtgtc
    74341 gatcgacggg tggaccgata tcggcgagcg gtgcgaactg catcccttcg tatcggtggg
    74401 cgggccgcct caacacatgc agtacaaagg cgagccgacg aaggtcgtga tcggtcacga
    74461 taacattctg cgggagtatg tgacggtcaa tcgggctact gttcaggggg gcggtgtcac
    74521 caccgtgggc cattccaatt tcttgatggc ctatgtccat gtcgcgcacg attgccatct
    74581 cggtaatcat ctcattctgg cgaatgcggc gagtctggcc gggcacattt ccattggcga
    74641 ccatgccatt atcggcgggc tctccggcat tcaccaattc gtacgtatcg gtgcctacgc
    74701 catggttggg ggttgttgcg cgctcggcca ggacctcccg ccgttcatgc gagcggccgg
    74761 tggctaccgc gcccgcatgt atggattgaa ctcgatcggg ctgcgccggc atggattctc
    74821 ggccgaacgg attgcggcgt tgaagaaggc ttatgaggta ctgtttcgct ccgggcatcg
    74881 tgtggcggaa gcggtcaaac tggcgcggga gcagttcggt gcgagccagg atgttctgca
    74941 agtcgccgac ttcatgcaag ggacgaaacg gggtatttgc cggtcggtgg gcaaagatca
    75001 ggaaggcgaa gaggaataac aagggtgggc ggacgtgcag cgcatgacag tcaggcgccc
    75061 gagggccagc ggatcggact gatcgcgggc aacggccggt ttccgatcat ctttgccgac
    75121 aatgcgaaac gcctcgggta ctccgtcttt gcggtggcgc atgaagggga aaccgatccg
    75181 gaattggccc agcacgtcga caacatccat tggatcaaga tcgggcaatt cggcaagttg
    75241 atcgacgcgc tcaagggcga cggcgtccag caggccgtca tgttgggcgg catcaagaaa
    75301 acgcacgtct ttaccacggt ccgtccggac ttccgcgcgt tggcgctggc ggccaaattg
    75361 attcatctga aggacgacga cattcttcgc cgcgttgccg aggaaatcga acaggaaggc
    75421 attcgaatct gcgaatcaac cttcggcctg caagggattc tcgtcgaagc gggcacgttg
    75481 acacggcgcg agccgagtaa aaaggaatgg gaagacatcc gttacggctg ggatgtcggc
    75541 aagcagatcg gcgcgttgga tatcggccag tgcgtcgtgg tgaaggatcg tgtgatcgtc
    75601 gccgtcgaag ccgtggaggg cacggacgga gcgattcgtc gaggtggtga attggcacag
    75661 gggggagcgg tggtcgtcaa gcgctgcaaa cctcagcagg atctccgctt cgatcttccc
    75721 gccgtgggcc cgcgcacgat cgaagtgatg gaagccgtca aagcctccgt gctggcactg
    75781 gaagccggac gcggcattct gctggatcgc gacgacacga ttgcgaaggc gaaccgcgca
    75841 gggatcgcta tcgtcgggat gacatgaagg cacacgcgat ggatgcagaa gccggcctcg
    75901 tcagacagga gaaggcacga tgacggcgct tcgtgccggg gtgatcggcg tcggccatct
    75961 cgggcagcac catgcgaggc attatgcaac gctccccggc gtcacgctgg ccggtgtgta
    76021 tgatgcgtcg ccggaccgcg ccaagctgat cgccgagcgt catggcgtgc aggcctggac
    76081 gaatctcggc gaggtgctca cgcaggtcga cctcgtcagc gttgcagccc cgacctctgc
    76141 ccatttcgcg gcggccaagg cctgcctgga agccggcaaa catgtcctgg tggaaaagcc
    76201 gattgccgtg acctccgccg aggcccacga actcgtcgaa ttggccgccc ggcgcggatg
    76261 cctgctgcag gtgggacata gtgagcgatt caacccgatc atgcagcgca tgcgtgcgtc
    76321 tatcgaacgt ccggccttca tcgaaggcca tcggctgagc gcgttcggcg aacggggcac
    76381 cgacgtcgat gtggtgctcg atctcatgat tcacgatctg gatctcgtgc tgtcgtttca
    76441 gcccggtccg gtggaggaag tccgcgccgc cggcgtgccc gtgctctcct ccaatatcga
    76501 tatcgccaat gcccgtatcg cgtttgcgag cggatgcgtg gcgaatctga cggcgagccg
    76561 cgtgtccacg aacaagatgc gccggttgcg attctttcaa cgcgaccgtt atgtctcgat
    76621 cgattttcaa tcccgtcagg cgatggtctc gcggcgggtg cagggcactg ggccgaggcc
    76681 gacgatcgat gtggaaacgt tccaggccgg ggacgaggag ccgttgcggc tggaactgga
    76741 atccttcatc catgccgtgg ccacgggatc gcgtcctgtc gtgtctggtg aggacggcga
    76801 ggccgcgctc aacctggctg gccgggtgtt ggacgccatt ggtcaattca cgcagcgcca
    76861 ttccgccggc gacgtctctg cggcggcatt cggccatgac agtctctagg ggggccacgt
    76921 cgatgttggt ccgcctgagc agagcgacat gccacgtatc ttaatcgtga ccggagaggc
    76981 ctccggcgat ctccacggag cccatttggt caaggcattg aaggagctgg ctccgtcgct
    77041 ccagatcgtg ggaatcgggg gtgcctccat gcgggcggcc ggcgcggagc tggtgaagga
    77101 tattcctcaa ttggatgtca tgggactcat cggtctgtct gcggtgaagg ccatgctgca
    77161 gaggatttcc cgcatccgcg cattgatcaa acgggagcgt tgggatctcg tggtcctgat
    77221 cgacaatccc ggactgaact tccattttgc ccgggtcgcc cgagcctgcc gcctgaaggt
    77281 tgtctactac attgcgcccc aagtgtgggc ctggcggcgt ggccggatgc ggtggattca
    77341 gcagcgggtc gaccatgtcc ttgcgattct gccgtttgag gaaccgctct ataagaaggc
    77401 cggcgtgcgc tgcacctttg tcggtaatcc gattctcgac gaagtggcct caacgtacga
    77461 ccgggaggcg ttgcgccgcc aattcgagct gtcggatgcg gggccggtta tcgggctctt
    77521 tcctggcagc cgcaaagccg aattgctgga acatgtcccc ctgctgatcg agacggtgaa
    77581 gcggctcgcg caacgccacc ccaccatgca atttattctg gcgcaagcgt catcggtgca
    77641 ggaccagttt ttggcggatc tcttgaagga cagtccggtt cccatcaaag tcttgcgtaa
    77701 ccaggcaagc gaagtgatgg ctgcgtcgga tctgctcgtc gtcaaatcgg gaacctctac
    77761 attgcaggca gcggtggtgg gaacgccgat gattttgttt tatcgtgccc cctcctgggt
    77821 gacgtatcga ttggcgcgcc tgttgatccg ggtgccctgg atcgggctgg ccaatctggt
    77881 cgcagaccgg ggaatcgtcc ctgagctgat tcatgacgaa gctacaccgg aacgcttggc
    77941 tcaagagacc gaacggctgc tggcggatcc tcgcgcctat gcggagatga aggccgccct
    78001 gttgtctgtg cggcaggcgt taggcacgcc gggggcctcc cgacgagctg ccgaagccgt
    78061 gctcgctgag tgccgatcat gaaacactat ctgcgcctcc tcgcatatct gaacccctat
    78121 cgattccgct tgggcgccgc attcgtgtgc gcgctgctcg tggccggctt gtccgccgct
    78181 tatgcctggc tggtacgtcc cgtgctcgat ggcctgttca tcagcaaaga tgaaagcctg
    78241 ctcctcgtcc tcccggtggc aattttgctc gtggcggtgc tcaaaggcgt gttcaactac
    78301 ggtcaaaact atctgatgaa ttatgtcggc aatcaggtga tcggcgacat cagagagcaa
    78361 ctcttctcca aattggttcg cttgcctgtc cactttcacg atacaaatac gtcaggacgg
    78421 ctggtctcgc gggtcatcaa cgatgtgaat cagatggcca atgccgtcgc cggggtgttg
    78481 aaggatctgt ttcagcaggg gctgacgttt ctggcgatga tcggggtgat catctatcag
    78541 aactggaagt tggccatggt gtccatgatc gtggtgccgc tgtccgtggt cacgatggcg
    78601 cggatgggca aaaagttgcg aggactcgcc acacgcggac aggaacgtat gggagacatg
    78661 gcgtcgactc ttcaggaagc cctggccggt atccggatgg tcaaatcctt cggccgggag
    78721 gaagacgagg ccaagcgttt tcgtcagagc aacgacgcgt tcatccatac cacaatgaaa
    78781 gcgattcagg tttcttccct gggttcctcc catatggaag tgatcggcgt gctcggggtg
    78841 gcggggatca tctggtacgg cggctatctg gtgattcacg atgaaatgac tcccggcgcc
    78901 ttcttttcct tcctggccgc catgttcatg gcctacacgc ccatccgacg attgtcaggc
    78961 gcgaacaaca cggtgcagca ggccctcgcg gctgcagagc gcgtctttga cgtgctggat
    79021 ctgccgacgg aacaagtggc caatggcggg cagacggagt tgccgcaaat ttcccgttcg
    79081 ctcgaattcc ggcaggtcgc ctttcagtat gaagggcagg gggatgcggc cctcaaagcc
    79141 atcgatttga cgatacgggc gggcgaggtc attgcgctcg tgggcagcag cggcagtgga
    79201 aagaccacgt tggtgagttt gctcccgaga ttctacgatc ccagtggcgg gcagattctg
    79261 atcgacggtg tggacatccg gaactgcaca ctgcaatcgg tgcgtggaca aattggaatc
    79321 gtgtcgcagg aagtggtgct gttcgacgat acagtgcgca ataacatcgg gtatgggcgg
    79381 cagggggcca cgatcgacga cgtcatgcag gccgcgaagc tggcctacgc acatgacttt
    79441 atcagccgca tgccggacgg ctacgagacg ttgatcggag agcgcgggct caaattatcc
    79501 ggcggcgagc gccagcgcct ggcgattgcc agggcgattc tgcgcgaccc tcccattttg
    79561 gtgctggatg aggcaacgtc ggcgttggat acgcaatcgg agcgcatcgt gcagatggcc
    79621 ctatccaacc tgatgcggaa ccgaacgacc ctggtggtcg cgcaccggct gtcgaccatt
    79681 cagaatgccg atcgtattgt ggtgctcgac cgcgggacgg tcgcggaaat cgggacgcat
    79741 gacgaattgc tgcgcaaagg cggcctgtat aagcgcctgc atgcgatgca gtttgccgat
    79801 gcgctgccgc agtaatcgaa ggatcgaggg tgacgtggtg agcgactcca tgacgaacag
    79861 gtctccggca gccccgcagc cgaaacaggc cctgacgaag cgtctcacca atgcactcaa
    79921 gctcgcggtg gtgccgcctg tcggctatgc tgtgattcgg ctcctgcaac gcacgatggg
    79981 ctggaggaca gagggcaggg aacatgtgtc ccggatattc gcgcagggcc agcaggcgat
    80041 tctcgcgttt tggcatgcgc agcagctgat gatgccgctg gccattcccg gtctcaaagc
    80101 gcatatcctg atcagccagc accgggacgg tgaattgatc tgccggatcg tggcgcgttt
    80161 cggattggat gcggtgcgtg gttccagtac cagaggtggc gcggaagcct ttcgccggct
    80221 ggttcgcctc ggacggtcgg gcggcaacct agtgctgacg ccggacggcc cgaaggggcc
    80281 gaggcaggtc gccaaggtgg gcgtggtgca gttggcgagg gcgacaggtc tacccattgt
    80341 ccccatggcc ttcggttgct caaaaaaaaa ctcttcgcga gctgggaccg gttcatcatg
    80401 ccctatccat tctcgcaggg gatcttcctc attggggcac cgattacagt cccgccggat
    80461 gcatccgctg aggacctgga gcgcctgcgc ggggagttgg aagcgaccct gaaccgcatg
    80521 acgatcgagg ccgatgcggc ggcccggcag gctcgtccgt aatgtggtat ctgctctaca
    80581 acagcctgct cctcctcgtt tctccggtca tcctctgtgt gttgctggcg aagcagcgct
    80641 gccggcgcgg gctaccccag cggctgggcc tgttgccgga gcagccgcgc gaggctgcgc
    80701 cggcgccaac ctgcatctgg attcatgcgg tgtctttggg ggaagtggtg gcggtggcgc
    80761 cgctggtacg ggagcttcgc cggcggtatc ccgaggcgag attggtagtc tcgaccgtga
    80821 cggaaacggg gcgtgaggcc gtcgagcaac gtttggaagg tctggccgaa caccggtatg
    80881 ctccgctcga ttttccctgg gtggtcaacc agacgatcga tctgctccgt cccaatctct
    80941 acgtcttcgt cgaaaccgag ctctggccca atctcctccg gagcctgcgg cgaaggaata
    81001 ttccctcgat tctggtcaac ggacggctct ccacccgatc gtttgagcgg cagcgcttgc
    81061 ccctgatccg ggatttttat cgcacgatgt tgaatatgat cagctgttgc ctcatgcaat
    81121 cggagcgtga tgcgcaacgg atggttgagt tgggtgccga ccaatcccgg gtccgttgca
    81181 ccggcaatat caaattcgac cagccggttc cacaggcggc cgccggcggc acggtcgtgt
    81241 cgaagcaggc cctgggactg agcgagcgcg agcggctggt ggtggcggga agcacgcatc
    81301 ccggtgagga agacatgatc gtggatgcct atcagtctgt atgcgaagag ttccctgagc
    81361 tccgcctggt gctggctccg cggcatatcg aacgggcagc gcaggtcgag cagatggtgc
    81421 gcgccaaggg gctgccggtg tctcgacgca gtaccggcaa gatggaatcg atggccacat
    81481 ccggtccgcg cgtggtggtc ttggacacgc gcggagaatt agcgttgttg tatcgggagg
    81541 ccgaggtggc gtttgtcggt ggcaccctgg tgcccatagg cgggcacaac ctgttggaac
    81601 cggctgtctg gggaaaaccg gtgctgttcg gaccacatac cgaccattgc gccgaagtgg
    81661 cgacgctgtt gctgaatgcc cggggcggcc gtgtcgtgga tggtgctcaa ggccttgcac
    81721 agagcctgcg ggagctcctc ggcaattctg acgatctgaa acggatggga caagctgcgc
    81781 agcaagtggt cgcggacaac cagggcgcgc ttcagcgcag cgcggagatc attgccacct
    81841 ttcttccacc atccgccaca tcgacccgct ccgaaggcgc tacgcgcgga gccttgccgc
    81901 atccacgatc ctcatgaggc cgatgcgaca atcctggttg cgatgggtgg gatatccgta
    81961 tgaggtagcg gccagacttc gcctgtgggg ctatgcacgc gggtggtttc agacacatcg
    82021 gttgcctcgc cccgtgatca gcatcggaaa cctcactatg ggcggaaccg ggaaaacgcc
    82081 cgtcgtcatg tacgtcgtcg accggttgat cgcccaaggc aaacgcgtcg ccatcctgag
    82141 ccgcggctac cggcggcgca gcaaggctcc acaattgctg gtgtcggacg ggcagcaggt
    82201 gttggtggga ccggaagagg ccggtgatga accctatctc atggcccgcc gttgtcctca
    82261 tgcggtcgtg gcggtggggg cagaccggta tgcccttggc cagtgggtcc tgagccgttt
    82321 gccggtggat tgttttgtgc tcgatgatgg atttcaacat gtgcaactcc accgcgatgt
    82381 ggatctcttg ttggtggacg ccaccgatac ggctgggctc agagcagcct tgccggtcgg
    82441 tcgcttgcgg gaacctcttt cagcagcggc ccgtgcatcg gctgtgctca tcaccagggt
    82501 cgatcgtgaa gaggcaggtg aacaggtctg gcggcagctg gtgcaggcat gcccggcgct
    82561 tccgtccccc gtctgtgtgg ggtttcccgc agaggaattc cggcgcatag gtggggatga
    82621 aggccggccg cgggatgcct ttcgcggccg ctcggcagtc attttcagcg ggatcggcaa
    82681 tgccgggtct tttcacgcag tagtggcgga gttgggtatc acggtgattg agacactggc
    82741 atttcccgat catgtgcact atacccatgc catgatggag acgattcgtg ccagagcaca
    82801 agcggggggc gttgacctgc tggtgaccac ggagaaagac gcagacaagg tggcgccctt
    82861 cctgaacgct gatgacgcct gttgggccat ccggcttcgc acgcaaatta tttccggaca
    82921 ggaacggctg gagcgactcc tgcgccttga gccggaaagt aggccggcga gcgatgcgta
    82981 aggaggagat ccgtcgcatc gtcgtgcgcg gtccgaattg gctgggcgac gctgtcatgt
    83041 gcgagcccgc cctcagtcag gtgcgcacgt tgtttcctca ggcggagatc acgctgctgg
    83101 tcaaaccggc catcgcggat ctgctggcgc agcatccggc ggtgaatcgc acattggtct
    83161 atgacgaccg gggacgtcac gcggggctga ccggcaagtg gaccttggcc ggtgtcttgc
    83221 gccgccatcg gttcgatctt gccattctgt ttcagaatgc gtttgaggcg gcgctgatca
    83281 gcttcctggc cggcattccc cgccgattcg ggtatgcgac cgatggccgg agtgtgttgc
    83341 tcaccgatcc cgtcgccgtg ccgccgcgta gcgcgcagag acaccaagtg gaatattatt
    83401 gggacctgct caaacccttg gggggnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    83461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    83521 nnnnncggca gccggtatct tgcgcaccat gcctgttgcg ggaatgtccc atcgatcatc
    83581 gctgtatgac cggagtgacg gtggagcagg tccacgatgc agcagcacga catctgccgc
    83641 tcgcggcccc tccctccctc attgtgccga cagtggtgaa acctgccttg tcacccacgg
    83701 cgctggcggg agtgaccgtc tttttggatc gcgacgggac gttgaatgtc gatacagggt
    83761 atgtgaagac gccggaagaa tttacgctgc tccccggtgt cggcgcggca ctggccagat
    83821 tgaaaggcgg cggcgcaaag ttggtcgtgg tgacgaatca atccggagtg gggcgagggt
    83881 atttcagctc aaaggatctc gaagcgatcc ataacaaatt gcgactcctg ctggctgagg
    83941 acggggtcac gctcgacggg ttgtacttct gtccccatca tcccgacgat cgctgtaatt
    84001 gccggaagcc gtctcgaggg atggtcgatc gcgccttagc cgaattgcag gtggacctga
    84061 gccgcgccta tgtggtcggc gacagtgtgc gtgatgtcga attggccaaa caggttggtg
    84121 cgcgggctgt gctggtcatg accggccctt ctggggccga ggcgctggcg gacctgacgg
    84181 cacgggatct tgctccggac catgtggccg ctgacctgtc gcatgcggtt gaatggacca
    84241 ttgcccacgc gacgcgcaag ccggttgccg atgtggcagg ttgagcgagc atcatccctg
    84301 gtggctgaat gaccgagcca gtccgccgca tcctactcat caaaccgagt tcgcttggcg
    84361 acatcgtgca cgcgatgccg accctggccg ccttgcgcga gcgatttcct caggccgagg
    84421 tgacgtggct ggtcaagcgc caatgggctt ccttcgtcga ggtcatcaaa ggagtcgatc
    84481 atgtctgcgc ggtggagcag gggttgagag ggtggttggg gcgcgtgccg gatcttcggg
    84541 cagcccggtt cgagctggtc gtcgatctcc aaggattgtt cagaagcggc gccatggcct
    84601 ggctgaccgg ctgcagccgg cgtgtcggat ttgccaatgc gcgcgaaggg agtcccttct
    84661 tgtataccca gcgcgtcgcc gtccccaatg gatcgatgca tgccgtcgac cggtatctgt
    84721 tggtggcgga ggccttgggt gcggcgcgtc agacagaccc gcggtttgac ttcgctgatc
    84781 gggctgaaga ccggggtgcc gcggaagcgc tgctcacagc agcgggtatc agggcgtcag
    84841 cgccatggat cgcgatgaac gtgtccgccc gctgggagac caagcgctgg cccgcgcagc
    84901 actttgcgga agcggcggat ctattggccg aggcacagca catacccgtt atctttatgg
    84961 gaggcccggc cgagcgcccc gagacgcgtg cggtgatggc gcgcatgcgc acgaaagcgg
    85021 ttgatctgac aggacagaca cctgtaggct tgctgcccag tttgttgcgc cgcgcagctg
    85081 tgttcgtgac gaacgattca gggccgatgc atattgccgc cgcggtggga accccggtgg
    85141 tggcgctgtt cgggccgacc gacccggtga agaccggccc ctatggccag gggcatgtcg
    85201 tcttgtccaa cccggtcgag tgccgcccct gttttcgtcg tgagtgctcc cgcgccgcca
    85261 cgctcgaatg tttgaccggc gtgacaccgg agcaagtcgt gcgcgcggtg cagcggcaat
    85321 tggggcgatt ggatacatca ggatcatcgt gaacattctc attgcggaat ccagtatggc
    85381 ggtcggcggt caggagttgg ctgtcctcct gcatgccgaa cgattggtgg cgcgaggcca
    85441 tcacatccgc ctggtgttgg agccgcgcag tcccatcatg gcgatggctc aggagcgtgg
    85501 gctcccggtc gagccgttcg tgatgcggca atggcgcctg ccgctgtcca ttcttgcgtt
    85561 ccgtcagttg ctcacgcgtg agcggcccga catcgttcac gtcaacagtt cgcgggacag
    85621 ctggatcgca gccctctcca cgcggctcct caatccgcgc cccaaggtta ttcgcacgcg
    85681 ccatatctcg gcgccgctga acaacaatgc caccacgcac ctgttatacc gtcgcctgtt
    85741 cgacatggtg atcgtcaccg gcggagaacg gaaccgccag gacctgatac atcgagacgg
    85801 cttgtcgccg gatcgtgtgg cggcgttccc gatcggcttg gatgtggaac agttttctcc
    85861 ggctcaaccc acgcacgata tccgtgctga gctcggtatt ccaccaaggc acttgctgat
    85921 cgggatgatt tcctacctgc gggactataa aggtcatcgc tacctggtcg acgcggcagc
    85981 caaggtgttg aaacaacatc cggcggcggc attcctcatt gtgggggagg ggccggagga
    86041 gcagaacatt cgtgctcata tcgaacgcct cgggctggca gccgatgtgc gcatgttggg
    86101 attccgtgac gatctcctcg acgtcttccg gtcgttgaac ctatttgtga tcccgacggt
    86161 cgagggggat acgattccac aagtgttgat gcaggctctc gcagtcggtc tcccggtcgt
    86221 gtcgacaacc accggttcga ttcccgatgt gattgccgac ggagagtcgg gttttctcgt
    86281 cccaccacgc gatcccgaag cgctggccga tcgcatcgtt cgtctcctga aggatgccaa
    86341 tctgcgtgcg gcaatgggga aacgcgggcg tcataccgtg gagcagtcct attcgatcga
    86401 ccggatggtg gatgaattgg agcgggtcta tcggaaggtc atcgcgtcat gatgctacga
    86461 tgggccgact cgggagcgtc tatccgcaaa agcgtgctgt tctggtggat tctgttcgtc
    86521 gtcatccaaa tggcggagcg ggtgtttctg ctgcgcgatg cgctcgacca ggagacgccc
    86581 acggcgtcgt tgctgctcaa aacactcctc gtcggtgtgc gaggagattt catcaccgcc
    86641 accttcgccc tcgtgctggg cggagtcggg gccggtctct actccctgtt gcggcagggg
    86701 gtagccggct ttcgccaatc accgcggcgc ttttcgctct cgtttcgccc ggccttccat
    86761 gtggggtgtc tgctggccgg attgctcctg ttcgtgctct tgtgtgtcga tatggggtac
    86821 tacggcttca atcatcagca tatggatttt gtgttcctgg agtatatcgg cgatctcctc
    86881 gcgccggccg cgacgactga ggggacgaac gtgcaggcca tgcaacagac cagcgcggag
    86941 ttggaagctg ccgggaaatg ggcctggcga ctgacggtct ttctgaccat tcaagcggca
    87001 ggcatcggat tgtggtggtg gagcttttca cgggcggtgg tgccggcgct ggaccgctgg
    87061 cggccgggct cgggttttca ggccaatgcg ttgttggtgg tggcactcgt ggccggcggc
    87121 gccgggtttc accattccgg tccgtacggc attcgcatcg cgccgatcgg cagcatggtg
    87181 tattacacgc tggcgcagaa ccccgtgctg tttgccgccg aggctttgcg gattgccgtg
    87241 gtatcccgca atccgatcga acggcgggcg aataccgagg ccatgcctta tgacctggcc
    87301 gtgcgcaccg ctcaacagtt gctgggtccc ggggagacat ttgtggatcc gcggtatccg
    87361 ttcgtgcgga cgacttcgcc ttcccccgat ggcgttcgac tgtccaagcc ggccaacatc
    87421 ctgttggtgt ttcttgaagg attggatcgt cgatatctgg ggcagaccta tggcgaggtg
    87481 aagggcaccc cctttctcga tcggctgaaa caggacagtg tctatttcca gaattttttt
    87541 tcgaacgggg tccaaacctc cagggggctg ttcgccacgc tctgcagtac ctttccgcgc
    87601 caaggcgctg ccgcaatgaa gacgcgatac gctcacgact atctgtgcct gccgtccctc
    87661 ctgcaacggc aagggtacag tacggaaatg gtgatcgggc agcatcggga cctgaaccgc
    87721 ttgcagacgt ttgtcgcccg caatggcttg caacaattgc tggacgaggg agacttcccc
    87781 gcgaatacgg aacgggcagg actgggcatt gtcgatggtg cgttgttcga cctctgttat
    87841 gaacggatca agctgcggca gtcccagggc aagccgtttt tcctctccac gctgacgctg
    87901 tcgacgcatc atccgttcgc ggcccccatg aatcatcctg aggttcagtt gcttcaacag
    87961 caggtgcagg ataagtatgt cgccgccttg cgatacacgg atctcgaact ggagcggacc
    88021 ttcacccggc ttgtccgcga aggattgctc cggaatacga tcgtcgtcat tctgggtgat
    88081 cacggccggc atgaaccggt gggagggtcc gatatcgagc gaaaggtcgg gcattttgcc
    88141 tcgccgttgt ttctgtggat ggacgaatcc ttacgaaccc ctgcgaccta tcggcctcga
    88201 gtcgtggata cgatcgccag ccaggtggat gtggctccaa ccctattgtc attgaacggg
    88261 ggactgccgg cgatgggagc atttgcggga catgatgtga gctgcgccct ggtgcaagat
    88321 tgcctgcctg gtcaggtggc ctatctgacg agtgtgtacg acaacctggt cgggcttgcg
    88381 agcgcagaag gactgttgtt gtattcgttc gcgacggaaa cctttcagga agccacgtta
    88441 cggttcgaac cggtaccgga tgaacaaaca ggcggcaggc ggctgtcggt gtcccgtgac
    88501 cgggaattga tggcgttata cgaagtcgcg aatgtcgcga tggattccaa tcgactgtgg
    88561 tcctggcggg aattcggaag ccgattgtga tcaccagtct gcggccgaag ctgaccgtgg
    88621 acgcgatgta aaaaggaccc ttctccgtgg atcgtatacc ggtatcggcg gtcgtcattg
    88681 cctacaacga cgaacccaac atgcgggcct gcctggaatc tattacctgg gcggatgaaa
    88741 tcatcgtggt ggattctcat agcaccgacg gcaccgaacg catcagtcgc gagttcacgg
    88801 acaaggtcta ccagcatgac ttccatgggt tcggacgtct gaggaacgaa gccctggcgc
    88861 atgccacgca tgactgggtg ttcagtctcg acacggacga acgggccact cccgaactgc
    88921 gcgacgaaat caggcggctg ttggacgccg ggccggaagc cgacgcgtat ttcgtgccgc
    88981 gcaaaaatta ttttctcggg cgttggatca aacattgcgg gtggtatccc gactatcgtc
    89041 aaccgcaatt gttccggaag agcaagctgc ggtatcggga tgaactcgtc catgaaagtt
    89101 tcgatctgga tggacgactg ggctacatga cggccgccgc gctccagtat ccattccggg
    89161 acatcgatca ttacctggcc aagcaggagc gctattccga tctgatggct aagcgaatgg
    89221 tcgaacaggg ccgagcgttt tcgtggcatc agctcgtgtc gcatccgtgt tttaccttcc
    89281 tcaagatgta tgtcgggcgt aagggatgcc tggatggtgt ccccggcctc attttgtccg
    89341 gcctctacgc ctattacaca ttcatcaaat atgcgcggtt ctgggaactg caatcccagg
    89401 gcgttcggca gccgaaccgg gttgccccgg cgaaacaagg ctaggcacag tatcgtgaag
    89461 caggacggga cggcatgacg attgcggcag tggtgatcac caaggacgag gagcacaaca
    89521 tcgcggagtg tcttcaatcg ctacggtggg ttgatgagct catcgtggtg gatgcggaga
    89581 gccgggatcg aaccgtcgag ctcgcaaagg ggtacacctc gaaggtgttt gtgcgtccct
    89641 ggccggggta cgggccgcaa aagaactttg ggatcgacca agccggtgcg gactggatcc
    89701 tggtggtgga tgccgacgag cgagtgccgg acgctttgcg gcaggaaatc caagcactgg
    89761 tggacagtcg acctcctgct gatattgggg gctacgaaat cccccgccgg aatgtgtttt
    89821 acgggaaatg gattcaaggc ggcgggttgt acccggacta tcaactgcgg ctgtttcgca
    89881 agacggccgg ccgctatgac gatgtgcgcc tccacgaaaa cctcgcgctg agcggccggc
    89941 gggagcgtct ccgggagccg ttcattcatt acagcatgcc caccgtgaac caccacatcc
    90001 gcaagatgat gcggtatacc acgctgggcg ccgatgaaaa gttgaagcgt gtccgccata
    90061 tcagcggctg gaccattgcc acgcaccacc tcggcactat tctaaaaacg ttgttcacgc
    90121 gcggtggata tcgcgacggc gtgcatgggc tggtggtggc gatgttcgcc ggtctccaca
    90181 ccttcgtgaa atatgccaag gcgtgggagc ggttgaacgt caggcgagac gcatgatggt
    90241 ctcggtgccc catcgccggc ctgggactga ggtctcgttc ctctgatgcg tatcgggatc
    90301 gacgcgtcct cattggtggg cgataaaggc ggcgttggct ggcatacgta tcatctgctg
    90361 aaggcgctgt tgcaactgga tgagaagacg gactacgtcg gttatctccg ccccggatcg
    90421 ctgcaagccg gtcaactcag cggttggcca tcacgctcgc gcatgcagtg gatggagacg
    90481 ccacggtggt tgatgtcctg gcgaggccgc tgggatcgtc ttgacctgta tcacggcccc
    90541 aattttaaaa tgcacacgac gggccggtac ggtggaattg tcaccatcca tgacctgtgg
    90601 ctggcccggc atccggaata ttcacgcaaa ctattcgggc aggcggggtc atcccgccgt
    90661 gcgattgcga cggcgaagcg ggcgcgcaag gttgtgaccg tctccgagtt ttcggcccgc
    90721 gaaatcgaat cgctgtatgg cattccacga gaccatgtga gggtgattta taacggcgtg
    90781 tcggaggact tcacgccact gtgtgacgac cagattcgag cggaggtacg gacacgatgg
    90841 tccattccct cgtccggctt cattctcttc gtcggtgggg ctgatccgag aaaaaaccac
    90901 gtgggatttt tacaggcggt gggcgcgtgc cgctcacagc tgggcggacg agccatcgtg
    90961 ctggtcggag acgcggagca tccccagggc agttatacag cgacggcgca gtcgctcggc
    91021 ttggagcagg aggttcgttg cacgggacgt ctcgaccgtg aagacttgcg tcgattgtac
    91081 tcctgtgcag acttgttcgt gttcccttcc cattatgagg gatttggcat gccggtgttg
    91141 gaggccatgg cctgtggtgc gcctaccgtg acatcttcga cctcatcgtt accggaggtg
    91201 gctggtgacg cagcattgct ggttgatccg aacaatgtgg aagaattggc ccatgccatg
    91261 gtgaccgtcc tgtccgatac gcatctcaga gagaatctgc gacagcgcgg atacgaacgg
    91321 gcgaggctct tcacctggca gcgcgcggca gtttccacca gtgctctcta tcgtgagctc
    91381 tgcacatgat agctactggc ctgctgcgcc cgaagaacat cctgatcatc aaattgcggc
    91441 atatcgggga tgtgctgttg tccacgccgg tgttgcgcgc cttgagagag gcttttcccg
    91501 ccgcgcagct gacgatgttg gtcaatcgcg ggacggaagg ggtgcttgcg cataatccgg
    91561 atgtgaacga ggtgctctgt cttgaaaagg gcgcatgggc cgaccaatgc aagttcgtct
    91621 atcgtctccg agagcgggga ttcgattgtg tgatcgacct gaccgatggg gaccgatctg
    91681 ccgtcatcag cctcgcgacc ggcgcaccca tccggatcgg atttaatgcg gaacatcgct
    91741 ggcgtggact cttgtacagc agggtggcga agccgcgccc cgtcgatcag catcgcgtgg
    91801 agtatgatct gtgcgctctc agagcgttgg gtctcgatcc caaacggggt atgccgtcgg
    91861 tctctgtgtc cgactcggaa gagcaggtga cggaccaatg gctgacggag cagggattga
    91921 tcggtgacca atgcccgccg ctggtgctcc tgcaaccggg ggcgcggtat tcgttgaaag
    91981 tctggccgcc tgaacggttt gcgcaattaa gcgatcgcct cgttgaacag tttcgttgcc
    92041 ggattttgct ggggggggac caacgggagc gtgaggtcgc cgaacaggtt gcccgaaagt
    92101 cgcattgcgc tcctatcgtg gtagcgggaa agttttccct gctgcagtat gcctcactgg
    92161 tgaagcggtg cgcgttgttc gtcggtaacg acggcggtgc catgcatatt gccgcgacgg
    92221 tgggcacgcc ggtggtggcc ttgttcggtc ccacctatcc cgagcgatgg gggccgcgtg
    92281 gcggattgac gcaggtgatc tacaaaggtc tggattgccg ggcctgttac catcccagct
    92341 gcttgcgcgg agacgatagt tgcatgcgcc agatcacggt cgatgaagta ttcgaagcgg
    92401 cgggccggat cctggatctg aagggtgcaa gggttgtgac atgaatgagt cggtcagtgt
    92461 cgtcattccc gttttcaacg gggcgccatt tgttgccaag gctgtggcca gtgtgcgggc
    92521 acaagcgcat ggtgacgtgg agattctcgt cgtggatgac ggatcgacgg atggcacaca
    92581 agaagtcctg aagcgcctgg aggagagtga cggcatccgg tggtttcaac ggagccacgg
    92641 ggggccggcc cggtctcgca attttggtat tgaagcggcg cgcgggcagt acatcgccct
    92701 gctggactgc gacgatgtat ggctgccggg aaagctggcc gcgcagctgg cgatcatgcg
    92761 cacccgtccg gaggtgggat tggtccacac ggattttgac gtgcgcttcg aagacgggac
    92821 gttggaagaa cgtgtcatcg cccgttcgag ccgcgagccg atggtgcagg cgttcgccgg
    92881 gggacatgtg gcattgccct cgaccctgtt gatccggaag agcgtgctgg atcaagttgg
    92941 acgcttggat ccggaactct acggatcgga agattccgat ctcacgatca ggctcttccg
    93001 ggtgaccagc ttcgagtgta tcgatcaggt gttggtgacg aaactgcagc gagggcatgg
    93061 gtatcgggac atggccttcg atgaacagac gcaccgggag cgggtactgg cgagccggga
    93121 tcgctttctc atgcgtctcg aagggtttgc gccgttgacg actgcgcagc gggctgcact
    93181 ggatcgggaa tgggccaatt actatctgtt gaaaggcgcg gccgcagaac gagccggtcg
    93241 cccggctgag gcgcggagcc agtatcgaaa ggcaatcggc aaggctcccg gccggatacg
    93301 ttgttacacg cgctggctac gcacctggac gtcttaactg cccaggcaac cctcatgtgg
    93361 aacaggtgat ggagacgatc gattgcgaag tgtgcggcgg gacgtcgacc acgacgatgt
    93421 tcagccaata cgatctcacc caccgcgtca ccgatgatgt gttcaccgtg gtgcgctgcc
    93481 tggattgccg tcaattgttc ttgaatcctc gtccgacgcg gcaagaaatc ggcagatatt
    93541 atcccgatac gtattaccct gatgcggcgc cccgccaggc cggagatctc cgccgtgctg
    93601 ccaaacggtg gtcggcaaca atcaggcgat ggatcgccca ggatttttat ggctatccgg
    93661 cacaggagca ggggcgagca tggcaacggg tacggcgaat gttcctctgg cctgagttct
    93721 tgtggcgctg ctggcgcggg cgtggcctgt tgccgtgggt ggggcaaggc cgtgtgttgg
    93781 atgtcggctg cggggcaggg ggaaatctcg cctcgctgca ggagcagggt tgggaggtat
    93841 caggggtgga cgcgagcgcc gtggccgtca cacaggcgaa ggcttgcttc ggggatcggg
    93901 tacgtctggg tgatttagag gcgatagcct atccggaccg gagcttcgat acggtcctgt
    93961 tcagtcatgt gctggaacat ctgcacggtc cgctgccgct cctgaaagag gtctggcgca
    94021 ttttggatca ggatggccgg atcgtcattc tctgcccgaa tgccggcagt ctggaggcca
    94081 agatctttgg tcgctggtgg tttccttggg agttgccccg ccatctcttt cattatgaaa
    94141 aggcgacgtt gcggcggatc ttggaagcgg ccggattccg gatcgaatcg atgcgcaccg
    94201 gcctgggttc gctctacttc atggctagcc tggaccgagt gtgtgagcaa cgattcggga
    94261 gggcaatacc ctgccgtcgt ctccttgaaa aatcgctgat ccgcccgttt tgtttttgtg
    94321 tcggacatct gggatatggg actgaactga aagtctacgc gaggaaagat gcgagcctga
    94381 atcaggctac acaaagtacg atctgaggag tcgggaccag gttttgaaat tgagcggttg
    94441 gtgacgcagg gcgaatcgaa atgcctgtcg cgcctcttgc cgggcatgcg cccgcaggtg
    94501 atgcttgccg aggtcggcat aataaatggc ccagtcgttc gacagggctt cgccttccgg
    94561 tgtgccgggc cggcaggtgg cggcatgttt ctcaagaaat cgccggcggc cgtccagtgc
    94621 gcgcagagag gggatgtctc tcgacgcatt gtggccatac agccgatgac ggtacatcgg
    94681 ttcagggagg tggatgaagc gttctggtcc atagagtcga atggccagat cgatgtcctc
    94741 ccagatcgag agggctgcat cgtagcctcc caccgagtcg aaccaggatt tgcggaacaa
    94801 tgagccggat gtggcggcat cgtggccgcc gcgaagcaat tgcgtaatgc tccgctgatg
    94861 tttcatcgct gcgtcgtact cgagaatatc gtttcgttca ttaacctggt atccgtcgca
    94921 atggacgagc accgcgcctg tggccggttc aaggatcgcc agggtccttt ctaaaaacgt
    94981 cggttcccag agatcgtcct gatcgagaaa cgccagatag ggagcctgcg ccagttgcgc
    95041 gccggtattt ctggcggcgg cttgtccggc gttcttggag tggcgtacgt atcgaacctg
    95101 tggaatagcc tgaaccagcg catccgtgcg atcggtcgac gcgtcatcca cgacgatgat
    95161 ctcgtagtcc gcaaaacttt gtgcctgaac ggaacggatg gcctcgttca agtacctgga
    95221 cgtaccattg tatgcgggga tgacgacgct gacgtgtgcc acggataaaa ttccttgtgc
    95281 cgtcacaccg gtaacacagg cggcaaaccc agtcaaccgc ggtaccattg ggccacccag
    95341 tgtgatggag ccggcttgcc ttgacttgac gggtgggcta tggttccatc ccgtcgcgtc
    95401 acgcagatct cctccaccag gggtccatcc agcgcaacct tgtgaagatc gtcatcgccg
    95461 cctggcacct gaaaaatttc aacgtgggga tcgggcggta tgcccgggaa ttgatcgagg
    95521 cgctggggag cgtggatcag acgaatcact atgacatcct ccttcctcag ccggaacatc
    95581 ctttcacggc gcggccgaat atgcgatatc gcgtggtgcg gtttccgctg tttcgccgtc
    95641 gattctggga gcaggttgcg ccgctgatgg ttggtccgta cgatgtgctg cattttccgt
    95701 acgattcctg cgtcgcctgg aagcgcggaa agttcgtgac gaccattcat gatgtcaaac
    95761 cgctgctgtt tcctgaactc cgtccccgca ccaacctcaa cagtcgtatc gaagactggc
    95821 ttgtagggga tcgttggcag acgatcgacc aggtgatcac ggtttcggag cattcccggc
    95881 gtgatttgct ggcgcatgtg ccgcttcgac cggaccaggt gagtgtgaca ccgcttggtc
    95941 ttgacgcggg gcggttccgg ccggccgaac atcggcatga gggcaggcca tacgtcttct
    96001 gcgtcgccgg atcagacccg accaagaatg tcggcgtgct cgttgaggcc ttcgcgacgc
    96061 ttcccgccga tttgcgcaac cggttcgatc tgatcttggc gggcgatgtg tgcaaacgag
    96121 aggatattcg tgccgctatt gctcggcgtg ggctcggcgc tcaggtcaaa ctggtcggcc
    96181 tcctgtccga tgcagacctc gtgacctatt accagcaggc tacggtattc gtgtttccct
    96241 cactctatga aggattcggt ctgccggtac tagaagcgat gggctgtggc tgtccggtga
    96301 tctgctccaa tgcgtcatcg ctaccggaag tggccggtga ggcggcggtc ctcgtcgatc
    96361 cgcgccggac ggaccaatta acgcaggaac tggccagggt tttggaatcg attgaattgc
    96421 agctgtcctt gcgtgagcgt gctctcgccc gctcaaaaga atttgtgtgg gaacggacag
    96481 cgaaacaaac ggtcgcggtg tatgaacgag cggttggccg gtaagaccgg cgcctacgat
    96541 atcgacgaat tttctagtct gaaccggagt gagacgttac gatcgacatg aaggaaggct
    96601 aggttcgcag gcggcagatc gtgctgacgg ctgtggtgtt ctgaagatcc tgttgcggag
    96661 ggggtgacgg atgaaaggag tcgtgcttgc cggagggctc ggatcacgcc tgctcccgct
    96721 caccaaggtg acgaacaaac atctgctgcc ggtctataac aagccgatga tctattatcc
    96781 catccagacg cttgtgaatg ccggaatcac ggaaatcatg ctggtaaccg gcggaaacag
    96841 tgccggtgat tttttgaagt tgttgggcaa tgggcgggac ttcggtctca aacatctcag
    96901 ctatacctat cagcagggcg aaggaggcat cgccgatgcc ttgcgcctgg cggaacattt
    96961 tgccgacgat ggtccgatct gcgtcgtgct cggagacaat ttgattcagg gcaacatcgc
    97021 gaaggccgcg gaggcgttca ggacccagaa gaagggcgca aagattttgc tcaaggaagt
    97081 gaaagatccg cagcgtttcg gtgtgcctca cctcgatggc aaccaggttc tgagtatcga
    97141 agagaagccg gctcatccca agtcctctta tgcggtgacc ggcatctatt tctacgatgc
    97201 ccgggtattc gagattacca ggacgctgaa accatcaggg cgcggtgaac tggaaattac
    97261 cgacgtcaac aatgcgtata tcgcctccgg cgagttgacc tggaacgtgc tcgacggctg
    97321 gtggacggat gccggcacaa ttgagtcact gcttgccgcc aaccaactcg tggcgcagac
    97381 cggtgcgaat aggatggagt tctaatgcga attctcgtga cgggtggcgc cgggttcatc
    97441 gggtcgcatc tggtgcgtcg attagtgcag agcggccgtc attcggtcgt aaaccttgat
    97501 gccttgaaat actccgggaa tctggagaac ctgacggatc tcgtggacca tcctcagtat
    97561 cgtttcattc atgcggatat cggtgatcag aaagctgtgc atgccgcgct gcaggaacac
    97621 cggattgagg gcatcatcaa ttgcgcggca gaaacgcatg tcgatcgatc gattcttgac
    97681 ccgggggcct ttgcccgcac cgatgtggtg gggaccggca ttctgctgga ggaggcgcgg
    97741 caggcagggg tgcagcgatt tctgcaagtg agcaccgatg aagtgtacgg cagtgtcgaa
    97801 caggggagtt caacggaagg ggaccggttg gaaccgcgca gcccctattc tgccagcaag
    97861 gccggcgggg atctgctcgt cttgagctac tggacaactt accgatttcc tgtcgtcgtc
    97921 acccgtggca gcaataccta cggaccgaat cagtatccag aaaaattcat tcccctgttt
    97981 gccaccaatg ccatcgacgg agaaccactc ccgctctatg gcgatgggaa acaatgccgg
    98041 gattggttgt cggtctacga tcatgccgcg gggatccagc acgtgttcga agatggccag
    98101 ccgggaactg tctacaatgt cggcggcggg aacgaacgcg aaaatatcat ggttgccgaa
    98161 cagatcgtgg cggcactcgg aaagtcgcga tcactgatcc g
//
LOCUS       DAOQPD010000005        88862 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_81_length_88862_cov_23.321506, whole genome shotgun sequence.
ACCESSION   DAOQPD010000005 DAOQPD010000000
VERSION     DAOQPD010000005.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 88862)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 88862)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..88862
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_81_length_88862_cov_23.321506"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(31..1020)
                     /locus_tag="PK063_02405"
     CDS             complement(31..1020)
                     /locus_tag="PK063_02405"
                     /inference="COORDINATES: protein motif:HMM:NF014798.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase C-terminal domain-containing
                     protein"
                     /protein_id="HMZ95918.1"
                     /translation="MRILTYAQAIREAHAQLLAEDPRVFLIGQGVRNPWYAGTSLQDL
                     DKEFGTHRVIDSPVSENATTGAAIGAAITGMRPIVFHPRMDFMLLAMDPIMNQAANWS
                     YLFAGRVSVPIVIRAVINRGGEQGAQHAQALQALFAHVPGLKVVMPATPYDAKGLLIA
                     AVRDGNPVLYIDDRWLYDLQGDVPEGLYEVPIGSAALRRSGRDVTVLATSYMSKEATK
                     AVETLTQRGIDVELIDVRSIKPWDRNLVYSSVGKTGRLVIADAAWMSGGIAAEIAASV
                     AGEVFHALKAPIGRVCLPDAPAPTSAALEEAYYIGAEEIVSTVEKVLVSSTRS"
     gene            complement(1025..2026)
                     /locus_tag="PK063_02410"
     CDS             complement(1025..2026)
                     /locus_tag="PK063_02410"
                     /inference="COORDINATES: protein motif:HMM:NF012880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HMZ95919.1"
                     /translation="MNFPDVHTGALSRDQLISLLRAMQRIRMAEERIGELVETREVRT
                     PCHLSIGQEAIPAGVCAALQQDDTLWGGHRSHGHYLAKGGDLRGMMAEIFGKATGCAR
                     GRGGSMHLVDPAQGIFGTVPLVAATIPLAVGAALSAKLRGTQQVAVAFFGDGATDEGH
                     FHESLNLAALYRLPVLFVCENNLYSTHLTLKERRVKDNIVESAALHGLPGVVVDGNDA
                     TAVYQTAHQAVQRARIGEGPTLLECRTYRWRGHVGPAADLEVGTDRRRELDDWQRRDP
                     IAQCRGLLKVHGLSSEVFDRLEAEIRREIDEAVSFARLSPAPDESELLQHVYARGGV"
     gene            complement(2023..2652)
                     /locus_tag="PK063_02415"
     CDS             complement(2023..2652)
                     /locus_tag="PK063_02415"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: protein motif:HMM:NF014453.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HMZ95920.1"
                     /translation="MKRVFDVLCAVLGLMLLSPMLVVIALLITLGDGGSPFYRGLRVG
                     RNGRPFRILKFRTMRSDAERSGVTSTAKDDPRVTSVGAVLRRYKLDELPQLWNVLCGE
                     MSLVGPRPEVQRFVDLYTDEEKAILAVRPGLTDWASLWNIDEGAILEGSADPDRTYCE
                     LIRPKKIRLQLAYVRQAGFRTDLDILLRTVGAVLFRVKFREPRVLELGA"
     gene            complement(3015..4193)
                     /locus_tag="PK063_02420"
     CDS             complement(3015..4193)
                     /locus_tag="PK063_02420"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF025025.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HMZ95921.1"
                     /translation="MSFTNSQAETPWVSGPFFHTYPIVSIIIPCRNERAFIAGCLESV
                     LANDFPKDRLEILVVDGLSDDGTREILDGFSRDHAFLSVLDNPKRVTPAALNLGIKHT
                     RGPIVMRMDAHARYDSHYISRCVDALGKYKVDNVGGIWKTLPRTETLAGWGVVKALSH
                     PFGVGNSHFRLPQGSEPKFVDTVPFFCVRRWVFQELGGFNESLVRGEDMEFSLRLNQP
                     GVFNERLTRGQDMEFSLRLRKAGGRTLLIPDIVSYYYARSDIKSFWCHNWINGVWAIL
                     PFAYSNVIPVSLRHLVPLFFVGSLVSTLVLTAWQGTFGWMFAGILGAYLLANVVASLH
                     VAWEARQPQYAVLMPIIFAMLHVGYGLGSLWGVVRLLTIREFWQKIFNVETNRAAPAR
                     "
     gene            complement(4221..5255)
                     /locus_tag="PK063_02425"
     CDS             complement(4221..5255)
                     /locus_tag="PK063_02425"
                     /inference="COORDINATES: protein motif:HMM:NF024863.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HMZ95922.1"
                     /translation="MFRVYYWTKDGIPAREWHRFFLGNFDGTMLDETLGWKATENYRA
                     NRAEKTKQGKSYVVTLSQNRYGFRQFGEIGSDKFKILILGDSFTHAREVSDSKTYYAL
                     LGRERPYEVFAYGVENYGTLQEYMILDRFFDLIKPDLLVWQYCYNDFANNDPLMERRT
                     MLHIDFRQRPYWSKGEIIRDMPSSILGKFRGLAYKYSRFIVFLLSRMDRLYAAYLLDS
                     VEAEILRSGAQHPDFRRAVRTTDELMATVRARVGATPVVAFNCKAVEPYNAALKNISG
                     RHDIIFLDEIAEAVDFAARQGRDVFHADGAHWSEEGHKLVGEMLVKRLEEFRVNRSLY
                     RYREAAAPPN"
     gene            complement(5345..6649)
                     /locus_tag="PK063_02430"
     CDS             complement(5345..6649)
                     /locus_tag="PK063_02430"
                     /inference="COORDINATES: protein motif:HMM:TIGR04370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008755 - O antigen polymerase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polymerase"
                     /protein_id="HMZ95923.1"
                     /translation="MFLFVQGVLILACIALIARIAEGSWLSPGALFALLWSWYSLTAL
                     LFRVPSETLILGIVWIAGSGVLMHLGCLWGTGSQRVENQCEDKRFIYPYLRAVTGTLV
                     FIGLVRISYIILDGSPSLGEALSVENLSQIVMQNRATFVYGSEKLTFIERVLFVAFYA
                     APLFGGILFQVAVSNMDKAIAVLAVIAPAAHNLLYGSRMGAMFGGAFWISAYMAARLL
                     GGRSGKAHSDVSNLRALICIAVAIVGTSLVVLSLRYGDEEVSTLSLLLLAASDIFSFL
                     PSFAILLDKGTFSFSDLTYGDRTFGRIFEFARLGTEDHYIYEAVDVGYTSSNVYTVFQ
                     GLIDDFGHIGALVSALIFGYIAGHSYHQVLRGKVVAVPFLTAVYAAVMISFSFSLFTY
                     TSTTLALISFGLYIVLMAKEVRPDSSLDSSRLRLSRHQSQSQ"
     gene            complement(6659..7702)
                     /locus_tag="PK063_02435"
     CDS             complement(6659..7702)
                     /locus_tag="PK063_02435"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013257.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 9 protein"
                     /protein_id="HMZ95924.1"
                     /translation="MKKILVVQTWGIGDMVMTTPMVHALRLAQPSAHICVVAGSDSAA
                     EVIRGSRLCEEVQVMSFRRSSMFTILRFFVRLRMQQFDVAFIASGLSPKIALGLKFLS
                     GVRTVVGDGGGAKGWGYTHWRRVDNTNHRVMENAEILKLALPNCGIGDLHFEFDEQAR
                     TEAARIWTNHHLDTCDVLGVHPGGQGSECPDKQIPQELCREVVQEYLARDETRRVVLF
                     FGPDETGLIKSYDWGLERVIILSGLRLTVVAATIGKCQAVLSGDTGLGHIAAAVGTPV
                     VTVAGPTDIVNTRPWGNKHRVVQTEKRPDCMPCYQTVLYGKCPHGQECMRSIDAAEVL
                     KVLMCLDDRQNVR"
     gene            complement(7709..9235)
                     /locus_tag="PK063_02440"
     CDS             complement(7709..9235)
                     /locus_tag="PK063_02440"
                     /inference="COORDINATES: protein motif:HMM:NF015013.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II flippase MurJ"
                     /protein_id="HMZ95925.1"
                     /translation="MSMGHESRTALSVQTWTSASALLFGVTGISKVLGFVRELLLASY
                     FGAGREIDAYAVAYAIPLFLAGGIGYAFSTAIIPGYHSMVAEHGKQAGLHYLSTSCVS
                     SVAWSFILLSPVWGAPEYLVKFAAPSMSAATIRLTVELMGWLSIYVLIQNCVYVLSAV
                     FHAFNHFRLPAVSDLLFNVVVIGVLMALASNVGVHALVIGNLGGIFICLLVLMGIILR
                     THGAHFGALSFTGLVHPILACLPVALYYVASQFPGLLANYFASGLGEGSIAAFSYART
                     IVAGLISLITVSVARAAYPTFASLFTYGREEQFREFVAGLARLILYGFLPLSVLCWVY
                     QKPLLRLLYQRGAFDEAALTLTATAFGFLAIGLTFGAWEPVGTRALYAAGDARSPLLA
                     TILSACLVVPLCLMLTPALGLAGVALSLALAFAVDSAMQVISLGWRLNSPIWKDLAWF
                     SMKCATCALFATTSFLVMPVDHGWQATGGGVLYICSYGLLTWWLVRPVRSMWNVAIVR
                     "
     gene            9352..11625
                     /locus_tag="PK063_02445"
     CDS             9352..11625
                     /locus_tag="PK063_02445"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95926.1"
                     /translation="MKPLLSHRFPISPLWSGLLLALLYLNVHDVLRAEESASPTTSHV
                     VDMRFSTTTFLLNLEKRGLEDNTFTNGLGRDTTLIGNLINATLYKRLLPSLEAEIGVF
                     ANMPFGHDHEISQVRPVVRLTYQPVEQITAVAGTIRTPHRDFHDAVFDNGNRFLRPIE
                     QGAQMLVDSTHYQQDLFINWEQAFRGSAPNRYDVGYAGQLKFGPLHFNGQAHWVRNGQ
                     ALFKLDRSFSTRDNLVVATGPELVLEPSRWFASTAWWHQIGISFTYLTSYNQADNGSD
                     ASRGRGYELRTWLDLAGWRPYLAFWKGRNFLSQQGDPEFRASNFPEFGLSKTIRLGKR
                     ASIEFGAQARRIRAFFTEDGLNYMNRDTFKWVNQEYLVFNWDWDTNHADLIGDVWASL
                     SRPFDDRQDAPSERRFTAKLDTLTYVYSISYHGVRQIGGIPVSNHTFAGQYLSPVLQY
                     RVSPQLTLDAGLFAGLPVGDTQSFHTVQPILSAQYEMVPDVRLVAGTLHRNHPFVDAL
                     FNDATLFSRPVEQGFQLLVDREHYQQDLFINWNQIETYQKAERFDVGYAGRVAAGPFA
                     LNGQVYWTHFGGAQYSEARTFFGPGLPRDRPAGNNFLTAFGPQFTWQPKQYWPQLSWF
                     REIDVMALYLTSQNEPTQSSSPIVRGRGYQLTAGVNLDGWRPYITLWRGEHFVTERGD
                     PAYYAGDFTEFGLFKDFILPAGFSLRLGGFGRTIERHLTHTEYALLNWSWDQTPWRGF
                     CQRPTLLHRSESSCGQS"
     gene            11717..12340
                     /locus_tag="PK063_02450"
     CDS             11717..12340
                     /locus_tag="PK063_02450"
                     /inference="COORDINATES: protein motif:HMM:NF024895.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HMZ95927.1"
                     /translation="MRRSSIGLLFLALLCIPAVTRAENYVAAGIGVNAPSFDTTDAGK
                     VSLQKDLFYGGKIGHYFNDRGYNWFGLEVDMYRSTPGIKQQTLPTSSNPRLSGPMPGA
                     DLQVHSLAFNALVRVTGYQYKVEPYAGLGIGLNVGNISNGNFRPEASFAPSFNVLAGI
                     RYYMTESIAPFIEYKYNFAQFKFDRSNVTADYRANLFMFGIAYHFGR"
     gene            complement(12429..14129)
                     /locus_tag="PK063_02455"
     CDS             complement(12429..14129)
                     /locus_tag="PK063_02455"
                     /inference="COORDINATES: protein motif:HMM:NF013188.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HMZ95928.1"
                     /translation="MTPDPIFFRDLAYVFIAAVVGGTSAYLLRQPLILGYVFGGILIS
                     PLTPGPSISDVHSFELFAEIGVILLMFSIGIEFSLNDLLRVRWVALLGGPLGIFLSIL
                     LSVGLGHLVGWTMIQSVVIGSVVSVASTMVLARLLLDSGDLRAKHGRVMIGITLVEDL
                     AVVVLTVLLPALGTLEPGRFATIGKALWLAVLILVPFSYLAAKAIPPLLTRIAKTQNA
                     ELFLLVSLSLGIGTAAVTQMAGLSLALGAFLAGLIISGSEYGHETLARLLSLRDAFVA
                     LFFVTIGILIDPRIVWSNLPLLGLMLGLILIGKFVIWTLVVRLFRYAWGTALLVGVGL
                     TQIGEFSFVLVQVAKTAGHVGEDVYNATLAASLLSILLNAPFVRYAPRWVAALHLRMG
                     RAAMPMQGGVQDEQAGHVVVCGFGRMGSTVGLALDHFGIAYTVIERDPDLVRQLRRRG
                     ISCVYGDASQTELLTAAGAERAALVIVALPVIHEASLTVRRLRGLNEKIPVLVRAHGF
                     REAEDLRAVGATEIILPEIEGAHTLIRHAFQALKVPKPDILAYIKSGQHFRASDADGE
                     "
     gene            complement(14587..14662)
                     /locus_tag="PK063_02460"
     tRNA            complement(14587..14662)
                     /locus_tag="PK063_02460"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14627..14629),aa:Cys,seq:gca)
     gene            complement(14764..15963)
                     /gene="ispG"
                     /locus_tag="PK063_02465"
                     /gene_synonym="gcpE"
     CDS             complement(14764..15963)
                     /gene="ispG"
                     /locus_tag="PK063_02465"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA];
                     GO_process: GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HMZ95929.1"
                     /translation="MHITRKKTRQIQAGSVKIGGDAPISVQSMCSTDTRDVKATVEQI
                     RQLETAGCELIRVAVPDDEAANALPKIKAAMSVPLIADIHFDHRLALKAAEVVDCVRI
                     NPGNIGAWWKVQDVIKAVNERGIPLRVGVNGGSLERPLLDKYGWPSPEALSESALNAV
                     HALEDEGFTNMKVSLKASDVHHAIDAYYLFSTQSNYPLHIGITEAGTAMTGAVKSAIG
                     LGWLLSQGIGDTLRVSLAADPVEEVKVGFEILKSLELRHRGINVIACPTCGRVEIDVV
                     RMANELEKKLGHIKTPLNVSVLGCVVNGIGEGKEADIGIAGGEGKGILFKKGKLMRKV
                     PMDELMDTLIHEVEQLAKEKEAEASGVTHNGSSDGQTEEGWELMGHAPDEQSTIVRDI
                     PVLPSKP"
     gene            complement(15978..17921)
                     /gene="dxs"
                     /locus_tag="PK063_02470"
     CDS             complement(15978..17921)
                     /gene="dxs"
                     /locus_tag="PK063_02470"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HMZ95930.1"
                     /translation="MSLLKNIHSPADLKRLSPEQFPELCQEIREQILAVVSNVGGHLA
                     SNLGVVELTVALQYLLDTPKDKIVWDTSNQAYTHKLLTGRREQFHTLRQYGGLSGFCK
                     REESAYDTFNAGHAGTGVSAAFGMVEAREQRGEKHKVVCVVGDGAMTAGMTLEGLHHA
                     GGTNKDFIVVLNDNQMSISRNVGAISAYLNRTFTGEFYARMREETGQLLRKIPHIGAE
                     MQKIARRAEELAKGAILPGLLFEELGFQYAGPIDGHNFEHLLPTLENVLKMKGPVLLH
                     VITKKGLGYQAAMDNPVWFHACPPFVRETGVPAKKAVRPSYTSMAVDALIKVARQDKR
                     VVAITAAMCEGTGLNAFEKEFPERIYDVGIAEQHAVTFAAGMAAQGMKPVVALYSTFL
                     QRAYDQVVHDVATQNLPVTFCIDRGGLVAEDGTTHHGAFDFAFLRHVPNMVVAAPKDE
                     NELQHMIKTCVSFDGPASVRYARGVSLGVPMDPEPTTLPIGKGELLREGTDVAIVAIG
                     VTVWPAMKAAERLAQEGISAAVVNARFAKPLDTELILKTAKNVRCLVTVEEGCKMGGF
                     GSAVLETLSEAGVMLRTKILGLPDWYIEQGPQDLLRERYGLTADGIYNSVKQLFGAGV
                     VADDAARLASLVGSLPHGDEQGS"
     gene            complement(18102..19100)
                     /locus_tag="PK063_02475"
     CDS             complement(18102..19100)
                     /locus_tag="PK063_02475"
                     /inference="COORDINATES: protein motif:HMM:NF022825.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3187 family protein"
                     /protein_id="HMZ95931.1"
                     /translation="MRHLVYFFCLIGLSCGLPLLAGAEGFGPFPVRNFQALDQLVLAM
                     PGERAAVLRKGDLDIRLEAANTATIARDREEQADVTMKFETVRAGLFLRYGLTERLEV
                     GAEIPAYHRYSGFMEGAILGVERGTTGVSPPRKALRDTGYAFNVSNGGRTMFQGSENA
                     TGLGDVSFYGKYQLLQETGSQPALSIRMAVKAPTGDTGQVFGSGHPDAGIGLALDKTF
                     ATGWILYANVNGIFPTGRIAGLDVQPVVSGLVAVEYLWTENFSITAQFDYYSPPFHGT
                     GTRVLDKGVTESVLGVSYRILPRLLWQVYGVENLDFITGSAADFTLSTVLTYRFRS"
     gene            complement(19130..20335)
                     /locus_tag="PK063_02480"
     CDS             complement(19130..20335)
                     /locus_tag="PK063_02480"
                     /inference="COORDINATES: protein motif:HMM:NF013283.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BamA/TamA family outer membrane protein"
                     /protein_id="HMZ95932.1"
                     /translation="MQRHYFSSIRILLALAGLMFLSSPAPAGADTQIFPVPSVSTSKN
                     DGNDAGLIAPILISDPDGELKYLMAPMLIQNSIVGSRAVFNLFKYDPGGRQMKLIASL
                     TEKIERKVLFDYVDPAFGNGQYFLNFGGTFFKNATSRFFGLGQSTVQADESNYTAREA
                     RAYWRLGLYANEVTQVSVGQRVRQVQLQRGATDLPFSVEQFPTVDGIQGESIIVGHRA
                     SFYYDTRDSLVTPTDGMSVMAYAELNQNVKNGDHPVYSRYEIEVKKLFPSESKRAILV
                     VRADLQATIGSQVPFFEQSSLGGQNNLRGFGMDRYIDKHLIAFSIEERIHILRTKLAG
                     VTADFELAPFLDTGQVFNSFKDVSFQDYRMTPGVGFRAIVRPNVVGRLDYGYSREGGA
                     IFAGLDFPY"
     gene            complement(20369..20983)
                     /locus_tag="PK063_02485"
     CDS             complement(20369..20983)
                     /locus_tag="PK063_02485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HMZ95933.1"
                     /translation="MHVRRWMVVGVLLALQLFVGGLSFALAGPATESIRGTVDEVLRI
                     LNDKELKAPAKHEDRRQRLEKVVAARFDYSEMSRRSLGAQWNQLSDKEKQEFVDLFRT
                     LLTNTYADRVETYSGEGVQYLNERTEKEYAEVRTKVLSGKTEIPMDYRLLNKSNDWHV
                     YDVVVDGVSLVNNYRGQFTKILHTSSYSDLVDQLRKKSEKIKAP"
     gene            complement(21070..21513)
                     /gene="mlaD"
                     /locus_tag="PK063_02490"
     CDS             complement(21070..21513)
                     /gene="mlaD"
                     /locus_tag="PK063_02490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015914 - phospholipid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipid asymmetry maintenance
                     protein MlaD"
                     /protein_id="HMZ95934.1"
                     /translation="MERAKLELMVGIFVLVGIACLGYLSIKLGKLEVIGGHNYPIEAE
                     FTSASGLKPGASVEIAGVEVGRVRTIGLNSDRALVALAIQDGVKLYSDTIASIKTRGI
                     IGDKYLALSVGGGGDPLKPGDKIRDTESGLDLEELVSQYVHGKVN"
     gene            complement(21525..22286)
                     /locus_tag="PK063_02495"
     CDS             complement(21525..22286)
                     /locus_tag="PK063_02495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ95935.1"
                     /translation="MIKLVGVEKTLGKQAVLRGVDLTIPTGKLTTIIGRSGEGKSVLL
                     KHIIGLMQPDRGEVWIDGTDIARLKGRALNEVRKKFAMLFQGAALFDSMTVFENVAFP
                     LREKLRLKGDVVTRRVEEKLEQVGLKGMGHKFPAELSGGMRKRAGLARALVMEPEIIL
                     FDEPTTGLDPLMAKAIHDLIVAMQQQFRFTAVMVSHEIPEIFGISDYVAMLKNGRIAE
                     MAPSSEFVKTTDEEIREFIFVGGTVAPKGLPAESR"
     gene            complement(22371..23138)
                     /locus_tag="PK063_02500"
     CDS             complement(22371..23138)
                     /locus_tag="PK063_02500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HMZ95936.1"
                     /translation="MEGIARIGRFTIDLTEQMGRMMLFVLSSFAWLTRPPFRFYQIVK
                     QLNFIGYKSTFVVVLTAVFTGMVLALQGYYTLRKFGSEAVLGSAVALSIIRELGPVLA
                     ALMVTARAGSAMTAEIGIMRITEQIDALDTMAINPLQYLIGPKLVASLIAVPLLVALF
                     DVVGIYGGYVVGVQLLNGNEGAYWSSIESAVEWKDVYGGILKSISFGLLISWVCCYKG
                     FHTKHSAEGLGTATTEAVVLSAVLILVWDYFLTSVLL"
     gene            complement(23193..23948)
                     /locus_tag="PK063_02505"
     CDS             complement(23193..23948)
                     /locus_tag="PK063_02505"
                     /inference="COORDINATES: protein motif:HMM:NF013232.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95937.1"
                     /translation="MTTIGVFVATRWELAAVRHAFPASEVRAVGGIRCVVVRQPFVEW
                     CIIPMGVGPERAMATAKRILAEQALSAIWSTGFACALGPAGIGDVLIGTDVILENGGK
                     AGPSVPCAPAMVEWVRQAVHVQGLPMRSGGFVTVPRVLCLAEEKRAIAGRAGGIGLDM
                     ESAALGRVASEHRIPFAIVRTVSDLEDESLPLDFNLFLRPSGWAKGVVACLAHPTSLI
                     GLNRLRVQSQIAGAQLTALFRACADRALGEGIG"
     gene            complement(24003..26174)
                     /gene="shc"
                     /locus_tag="PK063_02510"
     CDS             complement(24003..26174)
                     /gene="shc"
                     /locus_tag="PK063_02510"
                     /EC_number="5.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="squalene--hopene cyclase"
                     /protein_id="HMZ95938.1"
                     /translation="MRLLKNLFSRLSDSLLVSVPSRIRAARDFASAPVLRLVSSKPDA
                     PASDGAKRAPSHTTGQLEALEEAIRKSQAWFLARQDTTEGFWVAELEADTTLSSEYLM
                     LRRFMNCVDPERERKVIRYLKSAQLPCGGWPIYHGGPADISASVKAYFALKLSGVSAD
                     EPFMAQARTCILDKGGVVAANVFTKIALALFGQYDWRGVPSMPPEIMLLPKRFYFSIY
                     AISYWSRAVLIPLLIIFAKRPQCYVPPEQGIDELYTQPPAEIDYSTVPPFKKDRTWFT
                     ARNFFINLDALLKVYDRSPVEWVRQKALKGAENWMLDHMKGSGGLGAIYPAMANSVMA
                     LNCLGYKNDDPLVVKAMREIEELEIHDTVMDNGQCVDALHLQPCHSPIWDTALLINAL
                     SEAGMSQDHPALQKAATWLLSKQTKTVGDWIISSPGAEPGGWYFQFENELFPDVDDSA
                     VVLMALAKVRLPDEDQQRLAIRRGCRWVTAMQGSDGGWGAYDVDNNRIVFNYIPFADH
                     RALLDPSTADLAGRCLEMLATLGYDWTHPSVASALTFVKNDQEQDGSWYGRWGVNYIY
                     GTWSVLSGLRAIGEDLSSPYIRRAVSWVESKQNPDGGWGESCLSYADVAESGRGDSTP
                     SQTAWALLALMAGGVTDSFSLARGIHYLIRNQRKDGSWEEVRHTGTGFPRVFYLRYHW
                     YCQYFPLWALAMYRNLKTRGTTRADELRQLAYQSGQFRSPR"
     gene            complement(26398..30081)
                     /gene="smc"
                     /locus_tag="PK063_02515"
     CDS             complement(26398..30081)
                     /gene="smc"
                     /locus_tag="PK063_02515"
                     /inference="COORDINATES: protein motif:HMM:TIGR02168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HMZ95939.1"
                     /translation="MYLKSLEMLGFKSFAEAKIQFPKGITAIVGPNGSGKSNVVDSIL
                     WVLGEQSTKTLRSEKMEDVIFNGTEVRKPLGLVEVSLVIGGLGELRLDAISGLPSQLS
                     EYQELMITRRLYRNGDSEYLINKTPCRLKDIRNVLIETRAGSKGHTVIEQGRIEQILQ
                     ASPQDRRELIEETAGIVRYKKQKAEALRKLESTQQNLLRVRDIVAEVKKQLNSLERQA
                     RQARTYQTLQQEAKGLEIELLSRDYRTMHADLESVDREAREVEALEAEQVAEQARLDS
                     EQEAIRLRMNDTAEAISRVRDTLAGTEQRQSQALTAAEVERNRTELFERQRVQASQEM
                     ERLAGDQEQAQVEIEDLRATLLQLEGDIVEQEAQFQQADAEAKALAGHRAAAVSEEER
                     ARKDVLNLAVLVANTEQSLAQVTARQQETSARAERVSREQEQMVAQVAGLDEQRELLA
                     AQREEASQRIQGLMAERQAAIERIEGLGGQITGLDRDIVRFSEDVAAVESRLGALQGV
                     VREEMGYGREGEEEGTALKTCDGVREALAEWLVIPSGLDRAVETILGERVRGWLVDQP
                     SAASRAVEFLKGKELGRGAFIPQQIRWATDQAAADSSASWWPALNGQPGVVGRAIDVI
                     RAEGASASTLSYLFDGIVIVESLAVALQLWEQHQWPAPAGPTYVTLSGETLDAAGVMT
                     GGGTSAGAGLLQRRREVLELEARRMEAVQALELARVAREEAASALGLGREEEQQLGRA
                     IREAEMLELSLQKDDTNVERQRGELHRRMDMLAEELQRGLAEQARLQEQLESSQAQLE
                     QWVAEKLGQENGLLQIRERLVVIESQGLAIQQRLTEVRLSLESMRGRREHAHSDIARF
                     TQRLDAAQRRAAELEEQVTGLVQATESSREEQTRQEALCRELGAEVDGIKSELIAAQE
                     RQAEEMSGLHTVEETLSTVRQSLSALHDRRMTAEVRKAEVKAHLSTIESTLAGTYQID
                     PATLLVVSTEEQPVTEGEEPPAPVSLLETPQLREQIQKIRERLDRMGAINLAAIDEHR
                     ELEERYQFLTTQEQDLSTSIASLKEIIQKINRTTKDMFVETFNELQQKFRDVFAQFFP
                     GGRAELQLVEEPLEEGVEDNGAREPGVEIVAQPPGKRLKSITMLSGGEKTLTAMALLI
                     ASFLIRPTPFCILDEIDAPLDEENIGRFTSVLRSLSSTAQFMVITHNKRTMAMADSLF
                     GVTMEEPGVSTLISVKLGDLQPA"
     gene            complement(30272..31234)
                     /gene="ispH"
                     /locus_tag="PK063_02520"
                     /gene_synonym="lytB"
     CDS             complement(30272..31234)
                     /gene="ispH"
                     /locus_tag="PK063_02520"
                     /gene_synonym="lytB"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051745 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate reductase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA];
                     GO_process: GO:0050992 - dimethylallyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HMZ95940.1"
                     /translation="MKIYLANPRGFCAGVDRAIDIVDLSLKKYGAPIYVRHEIVHSRH
                     VVNSLRHKGAVFVEELNEVPEGSVVIFSAHGVAKSVWEEAQSRRLHVIDATCPLVIKV
                     HNEVNRDYTQGYELILIGHAGHPEVIGTLGQIPDKFHLVSSVQDVETLHVEKTQNLSY
                     VTQTTLSVDECRDIVEALHRRFPNIKGPHQEDICYATQNRQNAVKALSKLVDVILVIG
                     SPNSSNSNRLRELGEHCGIPSYLIDAASDINPDWLKDAKSVGLSAGASAPEVLVTEVV
                     AYLKRLGSSEEVEELTVIEEDVEFLLPKELVTIESASRTAASAN"
     gene            31409..32125
                     /locus_tag="PK063_02525"
     CDS             31409..32125
                     /locus_tag="PK063_02525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ95941.1"
                     /translation="MSSPSSTHKKILIVEDEKDILQLVKLYLEKEGFRTVSAMTGTEG
                     LRQVKAEHPDLIILDLMLPELDGLEVCKRIRLNQETALLPILMLTAKAEESDTVIGLE
                     LGADDYVTKPFSPKALVARVKALLRRLDRNANSPQTQYHYGPLTVDLSRHEVRLEGEE
                     VTLTAKEFGLLEHLLRNVGRVLTRDVLLSAVWGYDYYGTTRTVDVHVRRLKQKLPLLD
                     DAIISIKSLGYKLRESDIPA"
     gene            32122..33981
                     /locus_tag="PK063_02530"
     CDS             32122..33981
                     /locus_tag="PK063_02530"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ95942.1"
                     /translation="MNLSLRWKVALGTLAAVLVGLLVAGWLVIRSVEQTELSRMAEML
                     ETRSSLAAMALRPLFDQTGQAVPSPLLHTTIRELSQQARLRITVIKQDGTVLSDSAVP
                     AEGLTHIDNHLARPEVAQALASGRGMDIRASQTTGERTYYVARLLSEPARIQPGVPVI
                     RLGLPLTSIDERVRHIQQDLLTAFGAAFLLAMVLSLWVSRNLTKPLSEMAAAARQLAA
                     GTPGIRLTVSSSDEVGLLARTLNQMTDQLETKIKEVSDDRAQLLAMLIAMVEGVMVLD
                     YRGTVVQVNPALERMFALELTESRGRHYAELIRHEGLTALVSAVLQTRSGQGGEITLS
                     PSGSCLRVEASIAGGNREQEACAVFVFHDITELRRLEKIRKDFVANVSHELRTPLTSI
                     KGYVEALLDGGKDDPSTAAAFLEIIMRQSNRLNLILDDLLQLSQIESGQVLFRREPVE
                     LRALLERTVAVIKPLADKKHHTIELSLPDEYVVVEGDEERLVQVFINLLENAVKYTPD
                     QGRISMAIRQATQSRTASPRPMIEIVVADSGIGIPEADRPRVFERFYRVDKARSRELG
                     GTGLGLAIVKHIVEAHSGHVWVEGNAPRGSRFVVHLPVAQESSTTISTAAGNI"
     gene            complement(33947..34939)
                     /locus_tag="PK063_02535"
     CDS             complement(33947..34939)
                     /locus_tag="PK063_02535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter"
                     /protein_id="HMZ95943.1"
                     /translation="MAELSGLLLVVVILALLFDFSNGWHDSANAIATVVSTRVVSPST
                     AVLVAGALNVAGAFMSTAVAKMVGTGIVDPQSVTQTVVASALAGAIVWNFMTLMLGLP
                     TSSSHALIGGLVGAALTHGGMAAVKFSGLRSVLEAMILSPFFGFAIGLVLMIVLSWLF
                     FRVPRALALRLFSRLQLVSASFMAFSHGANDAQKAMGIITLALVSAGALPKAEVPTWV
                     IGSCALAMGLGTAVGGWRIVRTLGMRIVKLEPVHGFAAETGAAIVLMATAHIGLPVST
                     THTITSTVMGVGAVKRVSAVRWGVTRRILSAWLFTLPGAALLSTICYLLLSKLS"
     gene            complement(35004..35621)
                     /locus_tag="PK063_02540"
     CDS             complement(35004..35621)
                     /locus_tag="PK063_02540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF47 family protein"
                     /protein_id="HMZ95944.1"
                     /translation="MFGLIPREEAFFDLFKNAAHNMIEGSRLLKDMTEDFRNPVEKAK
                     RIKDVEHVGDGITHDIARKLNQTFITPIDREDIHDLASALDDILDVVEAIADRFVLYK
                     VVAPTEAAIRLANVLYQAAVEVGATVDLLGKSHQAVTECSVRVNSLENEADRISRDAI
                     SSLFEKETDPIAVIKWKEIYENFEAGTDRCEDVANILERIALKHT"
     gene            complement(35646..36638)
                     /locus_tag="PK063_02545"
     CDS             complement(35646..36638)
                     /locus_tag="PK063_02545"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HMZ95945.1"
                     /translation="MKCSRIVGTGSFVPPRVVHNEEVGKPLGLNSDQITALTGIRTRH
                     WAEPGQASSDLAVEAGRRACEAAGIPPQSLSAILVSTTSPDSAFPSTACHVQRALGAE
                     SVMAFDLSASCSGFLYGLSMADAMIRSGHIRSCLVVAAEVKSRSLDPADRETAVLFGD
                     GAGAVVLVQEESIRPQAAGILGVRLYAEGAGHGLITIPAGGSRKPSGTETVRGKDHLL
                     RMRGSAVFRAAIRHLEQAMLELLKEFGLSTVDVRRVIAHQANARILEQLRRRLGLPRE
                     VLYSVIERYGNTSSASLPIALDCAVREQRIAAGDVVVLAAFGGGLTWATGLVRW"
     gene            36840..37742
                     /gene="bamD"
                     /locus_tag="PK063_02550"
     CDS             36840..37742
                     /gene="bamD"
                     /locus_tag="PK063_02550"
                     /inference="COORDINATES: protein motif:HMM:TIGR03302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0065003 - protein-containing complex
                     assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamD"
                     /protein_id="HMZ95946.1"
                     /translation="MHRHSRDWCVRIAVMVGLLCFSAGCSSKPKTTAQGKPVSGTDEQ
                     IFLGDTIEKNYDPNVIMKRGEAFFDKEEFAEAIVEYQHFLELHRSHQLAVYAQFRLAE
                     SHLRMGKSIDRDPDPIQKAITAFEKLRKDYPNSKYEAQALQRLADCHDWLAKTHLFVG
                     QFYYRRSSYLAAAHRFDMIMKDYPDKTVAPEALYYLALTYQELGANDWAMEKLQLLAE
                     KYPNSDVAGSGRRLLAKLEKKSPPAAIVASKETPAPQSPPSNTLLAASVPSTFAAPAV
                     PELKRAPSAALSQPFVSCRLGAWC"
     gene            complement(37768..>39070)
                     /locus_tag="PK063_02555"
     CDS             complement(37768..>39070)
                     /locus_tag="PK063_02555"
                     /inference="COORDINATES: protein motif:HMM:TIGR02032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0045550 - geranylgeranyl reductase
                     activity [Evidence IEA];
                     GO_process: GO:0015995 - chlorophyll biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0030494 - bacteriochlorophyll biosynthetic
                     process [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="geranylgeranyl reductase family protein"
                     /protein_id="HMZ95947.1"
                     /translation="LRLFLTSPTQQQFLTMVAEDLRGKPFHNRCVTMADGYGPTTYDV
                     IIVGMGPAGATAAAALSRGGLTVLGLDKDAHPRYKVCGGGLSARIDHALEPGFHSVVE
                     QSVTGVQFVYRGQDPLLIESARPIAYMVMRDRFDHYLVQEAIQAGAHIRTGHGVVELM
                     QDQHGVEVVTAQGRYRAQIVVGADGANSVVARRFFPQRSQYRAPALESEVPLGNGRHG
                     HSASTILVDVGAARQGYGWIFPKRACLSVGVGEFRRKSKSLRATFDRFVTDEQHVIGG
                     AVPRPAGHPIPVYTESEKREQDEESRFVAGRAALVGDAAHLVDPLFGEGIYYAIRSGQ
                     LAAHAILAHRDDHHMAVSAYAAALRREILPDFRVTARMAQVIYAFPRLAFKLLGRYQD
                     VVQDYFEVLQGRTTAQQFLPNAKNRLKASVNDLLLEALHLR"
     assembly_gap    39071..39170
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(39248..39994)
                     /locus_tag="PK063_02560"
     CDS             complement(39248..39994)
                     /locus_tag="PK063_02560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis protein CcdA"
                     /protein_id="HMZ95948.1"
                     /translation="MTDSVQSISLVAAFSAGLLSFVSPCVLPLVPSYISYITGLSIEQ
                     LTDVSERSRFRKAIILNSLLFIAGFSTVFVAFGASASLLGQVLITYQEHLRRFGGIVV
                     IVFGLYLLGILNLNFLKMEHRYQFRNRPAGFLGSFLIGIAFAAGWTPCVGPVLGTILL
                     YASTTESMFSGVVLLTFYSLGLALPLFLTALGVDRFLSYFKEVRSYLWGVSTVSGVLL
                     IVVGVMIYGNSLTMITSFLERYGIGWYLGQ"
     gene            complement(39996..40550)
                     /locus_tag="PK063_02565"
     CDS             complement(39996..40550)
                     /locus_tag="PK063_02565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HMZ95949.1"
                     /translation="MMLSIIVGGLMIGGVMIADAPWASPLLSPAPAPILVASPAPQVD
                     EEAPNFLLKDSEGFNVTLDQFRGKVVLLNFWATWCGPCKIEMPAMERLYRSFSRKEFE
                     ILAVSTDAQGTAVTRPFQQEVGFTFPVLHDADFRIGLQYGARQLPMTFLIDRKGIIRN
                     RIPGARDWSAPAGKRLVEALLQGS"
     gene            complement(40570..41193)
                     /locus_tag="PK063_02570"
     CDS             complement(40570..41193)
                     /locus_tag="PK063_02570"
                     /inference="COORDINATES: protein motif:HMM:NF020123.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HMZ95950.1"
                     /translation="MSDILNQSSSGVTTRSGPSRTVVVLAAAAILGVMFLVVWLQSSK
                     YEPLIVGKEAPDFQLPDLNDKPLRLSDYRGKVVFLNFWATWCKPCREEMPSMEVLYKN
                     FEKDGLVILAVSIDRVTTKKEIPPFVKGLNLTFPVLVDSWGQTDKRYKLMGVPETYII
                     DQQGVLREKVIGPRDWTRLDNLKVLTQLLKPAEKAASAATVEAVPAL"
     gene            complement(41197..42111)
                     /gene="ccsB"
                     /locus_tag="PK063_02575"
     CDS             complement(41197..42111)
                     /gene="ccsB"
                     /locus_tag="PK063_02575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="c-type cytochrome biogenesis protein CcsB"
                     /protein_id="HMZ95951.1"
                     /translation="MMRSLFLFDMTFWLYLAALGLYVAYLFAKRPAMQMAPAGHPIEN
                     LEDRDGAWATQLGQVATLVTVFGWVLNTMALMTRAFERMEHSGTFAPWSNQFEAMAYV
                     SWAIILGYVLLEFRYRIKAVGAFVVGIGFIAMGAASLLPYRYQTAEPLVPALNSYWIY
                     IHVSVTLTSYAAFAMAGGLGLMYLFKERAVNRGSQSRFYAAFPDLETIDELGYKAIML
                     GFPLLAFGIILGAMWANYAWGGYWSWDPKETWSLIVWLIYGAYIHARMTRGWEGHKAA
                     IYAIFGFLMVIFCFWGVNFLLSGLHAYA"
     gene            complement(42184..43620)
                     /locus_tag="PK063_02580"
     CDS             complement(42184..43620)
                     /locus_tag="PK063_02580"
                     /inference="COORDINATES: protein motif:HMM:NF016995.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis protein ResB"
                     /protein_id="HMZ95952.1"
                     /translation="MNDKPDAASEMSASGPSTSGLGWEEFSREVVDFFASIKLAMFLF
                     IVLAMTATIGTVIQQGERPETYVQEYGEEAYRWFLRLGFTDVYHTWWFTGLLGLLCVN
                     SLTCFHKRFPSVWRSMRQDKVSVSLAFIQGMKQQTTLSLNQPKETVAESLVRLFAEKG
                     YKVLAKSDPGEVTVYATKGIMGRVGAHVAHLSATVIVLGGLLGSYYGFSEFGVCLEGQ
                     TYHIPRGNFDLRVDKFWIDYHENGSVKSYNSTLTVIDQGAPTMTKTITVNDPLVYKGI
                     WFYQSSYGDAWDQIEAARINIKDKASDKVVATVDLEWNKEKAVEGLPLKMKMTDFVAD
                     FAFNSTEKKVFSKTAEHSNPAIRLAVDERSTVQSTPWVFYHYPDLFEIKDSAYQFEFI
                     GYQPKKFTGLQIARNPGIMMVWIGCTMLVVGMTLSSLIYHRRLWARILPGESGVTVHL
                     GGTTHKSQIDFQKEFKKLTEKIQAKTSS"
     gene            44018..45166
                     /gene="metK"
                     /locus_tag="PK063_02585"
     CDS             44018..45166
                     /gene="metK"
                     /locus_tag="PK063_02585"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HMZ95953.1"
                     /translation="MRHNYLFTSESVTEGHPDKIADQISDGILDAIIAQDKTSRVACE
                     TILTTGIAFVAGEISTKAYVEIPDIIRDVIKDVGYTDASWGFDSNTCSVLTSIHQQSS
                     DIAMGVDSGGAGDQGLMFGYATNETTELMPMPIVLAHRLTKRLAEVRKKKVLKWVRPD
                     GKSQVTVEYKDGKPFRIDTIVVSTQHSPDVTNKQIERDLMEYVIKPSMPKGLYDATSV
                     KHHINPTGRFVVGGPMGDTGLTGRKIIVDTYGGHGSHGGGAFSGKDPSKVDRSASYMA
                     RYIAKNIVAAGLASKCEVQLAYAIGVADPVSVLVDTKDTEKVAPESLDKLVRKHFPLT
                     PRGIIDHLKLRRPIFRKTAAYGHFGRNEPEFTWEKTDKAKALRKDAGL"
     gene            45273..46529
                     /gene="ahcY"
                     /locus_tag="PK063_02590"
     CDS             45273..46529
                     /gene="ahcY"
                     /locus_tag="PK063_02590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004013 - adenosylhomocysteinase activity
                     [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylhomocysteinase"
                     /protein_id="HMZ95954.1"
                     /translation="MDYDVKDMGLADQGKLKIEWAEATMPVLRLIRKRFEKEQPFRGI
                     RATACLHVTTETANLMKTLKAGGADVRLCASNPLSTQDDVAAALVKHEGIPTFAVKGE
                     DNKTYYRHIESAIAHKPHLSMDDGADVVSHLHSKRKELLRHVIGGTEETTTGVIRLRS
                     MAEKKVLKFPVISVNDADTKHMFDNRYGTGQSTMDGIVRATNRLVCGSTLVVAGYGWC
                     GRGIATRARGMGANVIVTEIDPLKGLEAVMDGFRVMPMDEAAPLGDFFVTVTGNLKVI
                     RGEHFAAMKDGAIVCNSGHFNVELDIPALEKLSKKKLAVRSGVDQYTLKNGRRVSLLG
                     EGRLVNLATAEGHPSSVMDMSFANQALGAEFIVKNYKKLEKKVYPVPADIDKEISRLK
                     LAGMGVSIDKLTKEQVKYLASWEMGT"
     gene            46861..47598
                     /locus_tag="PK063_02595"
     CDS             46861..47598
                     /locus_tag="PK063_02595"
                     /inference="COORDINATES: protein motif:HMM:NF014017.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HMZ95955.1"
                     /translation="MATVRIGLSGYSYKPWQGPTRFYPPTLKQAQFLEYYSTRYRTVE
                     LDGVWFRLPTLSAVTKWIEQTPAHFVFSVKAHRTITHVKRLRPDAASFLHTMLEHLAP
                     LAEKQKLGPILLQLPPNFKRNDDRLAEFLQGLPPTYRWVMEFRHDSWNHATVENLLRR
                     FRVAWAAVETDDRPAEYRDTADFLYARLRRSQYSNKDLTRWGEYFLQTRRNGKDCYAY
                     CKHEDEGSPWMWADQLLKIMNVGTLPG"
     gene            complement(47587..49221)
                     /locus_tag="PK063_02600"
     CDS             complement(47587..49221)
                     /locus_tag="PK063_02600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HMZ95956.1"
                     /translation="MLVFLIHVRDPQFYALPAKTRAKNGRIRVMGFPPIGIMSLSAVL
                     KRAGHECVMFDQAHPETPNEFIIEEIKRRKPALVGMSFLSTTSYPYAKILARQIRVAD
                     GSVKLAFGGVFASLNAGLVKLQCPEVDFVCRGDGEQLLLDLLDHIDDPKDVAGVTWAK
                     DGKVINNPNRAMERHLDQWPFPDRESLELDFVESMPLDVPAVLSMERFTTMQTSRGCP
                     WPCVFCDIPIFNEGKWRARSAQHVVEELKFLEANGYGSVYFVDDHFLLQPKRIDAICN
                     GIIDAKLSIQWGIEGRVDSVAQHLFPAMAKAHCRTVMFGIESGSQKILDRLQKEQTLA
                     EVETAVRNAKKAGIEIVHGFFTVGNPDETVEDMEKTFDFASKLPLDTFGFNRLCVYRG
                     TPLWQEYIKRGLVSDAKDWYKYFKCSEIDPTCLPGATINSVRQEGLKKLFIYKLTRYP
                     IQTFKLLRRFLRYMPFRDVAYLIIKPFLGQKKGATKAEVLSRAVEHAEMKDAAAQLTQ
                     LSDELLHSVLEESKAERQRIQQEAESSRELPMISAR"
     gene            complement(49503..50375)
                     /gene="sucD"
                     /locus_tag="PK063_02605"
     CDS             complement(49503..50375)
                     /gene="sucD"
                     /locus_tag="PK063_02605"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="HMZ95957.1"
                     /translation="MSILVNKNTRVVVQGITGKEGSFHASQCKAYGTKMVAGVTPGKA
                     GQEVEGIPVFNTVADAVKKTDCDTSLIFVPPPFCADAILEAADAGVKLIICITEGIPV
                     NDMVKVKRALHGRDVRLIGPNCPGVITVDEAKIGIMPGFIHKRGVVGVVSRSGTLTYE
                     AVHQLSTLGLGETTCVGIGGDPVNGTGFVDVLPLFEKDPETQAVVMIGEIGGDAEEKA
                     AEYIKQHVKKPVISFIAGITAPPGRRMGHAGAIISGGKGTATEKMKALESAGVRVVKN
                     PAEIGHAVMKALGR"
     gene            complement(50387..51565)
                     /gene="sucC"
                     /locus_tag="PK063_02610"
     CDS             complement(50387..51565)
                     /gene="sucC"
                     /locus_tag="PK063_02610"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-forming succinate--CoA ligase subunit beta"
                     /protein_id="HMZ95958.1"
                     /translation="MNVHEFQAKQLFAQFGVPVPRGKEITSPEGATAWANELNTPVFV
                     VKAQIHAGGRGKAGGVKITKDRGAIAGLAKELIGKTLITHQTGPKGRTVHRLLLEEGA
                     NIAKELYLSILVDRDTGWPTFIASTEGGMEIEEVAEKTPEKIIKEAIDPAVGFQGHNG
                     RNVAFALGLQSMEPAVINPFVQMLGNLYRLFMEKHAALVEINPLIITKEKTLVALDGK
                     VSFDDNGIFKHEDVQKMRDLNEEDPLEIEATANNLNYVKLDGNIGCMVNGAGLAMATM
                     DVIKLAGSEPANFLDVGGGATKDTVAAGFRILLKDPNVKGIFINIFGGIVRCERIAHG
                     VIEAAKEVKITVPLVVRLQGTNADEGRKLLAESGLKLEVANDLWEAAQKIVKLTGKAA
                     "
     gene            complement(51651..53252)
                     /locus_tag="PK063_02615"
     CDS             complement(51651..53252)
                     /locus_tag="PK063_02615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HMZ95959.1"
                     /translation="MDIHALQQIVHQTRDARRKQTIPKFSPADRDQLIHKYHPDYRAS
                     AYRPIRFGPNADDKTVVELAALLEGDSSIPEHLDLTPQYTADVLVIGGGGAGCAAALH
                     AHTSGAKVILATKLRLGDSNSVMAQGGMQISVAPEDSPVTHFLDTLKGGHMQNDHELL
                     KVMVEEGPSIAKWLIELGVLFDRQADGNLHVKKGGGSSKPRLLTCSDYTGLEIMRVLK
                     DEVLNQKIQLLEFCAAVELLSDDNGQCTGAIFKDLDNHRHVIVAAKSVILATGGIGRL
                     HIQGFPTSNHYGATGDGLCLSYRMGAKLDHIDTFQYHPSGAVYPEQLIGALVTEGIRS
                     EGGHLVNAKGERFVNELDTRDVVSSSIIRECEEGRGIRTMSGRIGVWLDTPLLDAEHG
                     PGTVEKHFPAMMMQFERFGIDISKDPVLIYPTLHYQNGGVKIDANSETNVKNLFVAGE
                     ASGGLHGRNRLMGNSLLDLMVFGKRSGLTAASRAGSMSQGKLTLNHLKRFRAEAKKHG
                     NSSGVISPMILPAYTRKEPERTATK"
     gene            complement(53321..54031)
                     /locus_tag="PK063_02620"
     CDS             complement(53321..54031)
                     /locus_tag="PK063_02620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="HMZ95960.1"
                     /translation="MAQEDTNVIDQPEVLRHKMVTIEISGKKYEVPEGITVIKALWHT
                     GQEVVRGAGCLGGFCGACATYYRTKDDPKVRTCLACQMAVEDGMSFTIMPPFPARKAL
                     YDIQSLKDPKQDLFNLYPEAPLCRNCNACTEACPQKIDVREGVWKAVFGDFKSVSEMF
                     MDCVMCGMCTPVCIADIAPNLVALYVSRAQGAHFTEKPQGLDLRIKEIQDGRFNDEWN
                     KVLAMNEQELADHCATVK"
     gene            complement(54115..56343)
                     /locus_tag="PK063_02625"
     CDS             complement(54115..56343)
                     /locus_tag="PK063_02625"
                     /EC_number="1.1.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004450 - isocitrate dehydrogenase (NADP+)
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent isocitrate dehydrogenase"
                     /protein_id="HMZ95961.1"
                     /translation="MGKADKIIYTKTDEAPMLATYSFLPIINAFTKAAGVTVELRDIS
                     LAGRVIAVFPEYLTAEQKQHDALAELGEMAKTPEANIIKLPNISASIPQLVATIKELQ
                     SQGYKLPDYPENPKDDKEKDIKSRYDKVKGSAVNPVLREGNSDRRAPLSVKAYARKHP
                     HKMSPWSPDSKTHVSHMKGGDFRSNEKSMTIPAATTAKIEFVGADGKTTVLKEKVALQ
                     AGEVLDATFMSVKALRTFLEEQIEDAKKQGVLWSLHMKATMMKVSDPKIFGHGVTVYY
                     KDVFEKHAETFKKLGVDPDNGLGDVYAKIKSLPDDQRKAIEADIQAVYQKRPPMAMVN
                     SDKGITNLHVPSDIIIDASMPPVIRDSGKMWGPDGKLADVKCVIPDASYAPIYHEVVE
                     FCKQKGQFDPRTMGTIPNVGLMAQAAEEYGSHDKTFKAPANGTIRIVDANGTVLHQHQ
                     VEAGDIWRACQVKDAPIQDWVKLAVTRARATGAPAVFWLDKTRAHDAELIKKVNAYLP
                     KHDTNGLEIKIMSPAEACRFSIERMKEGKDTISVTGNVLRDYLTDLFPILEIGTSAKM
                     LSIVPLLNGGGLFETGAGGSAPKHVQQFQEEGYLRWDSLGEFLALAASLEHLAKVGNN
                     PVAKILADTLDQANAKFLESNKSPARKVGEIDNRGSHFYLALYWAQALAAQTADKKIA
                     ERFAKIAKDLSDNEKKIDGELLAAQGKPQDVGGYYHPNDAKAAKALRPSATLNAIIDA
                     IA"
     gene            complement(56369..58612)
                     /locus_tag="PK063_02630"
     CDS             complement(56369..58612)
                     /locus_tag="PK063_02630"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003994 - aconitate hydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HMZ95962.1"
                     /translation="MSMDLAKALYAKMPEVFAKARKKFGRGLTLAEKILVSHADNFDS
                     QNWERGKAMLALRPDRVAMQDATAQMAVLQFMQANKKKAAVPSTIHCDHLIRAEMGSE
                     KDLLRALDENKEVYNFLASAAKKYGIGFWKPGAGIIHQVVLENYAFPGCLIIGTDSHT
                     PNGGGLGGLAIGVGGADAGEVMAGLPWEVLHPKLIGVRLTGKLNGWASPKDVILYLCG
                     LLTVKGGTNKIVEYFGPGAETISATGKGTICNMGAELGATTSVFPFDEKMVAYMKITD
                     RADLATFTQSHKDLLVADPEVAQSPEKYYDQIVEIDLSKLEPHVVGPHTPDLARPISK
                     LKAEAQEKGYPVELKAALIGSCTNSSYEDISRSAHVAQQALKAGLKAKASFLISPGSE
                     RIYHTMKRDGFMDTFEKLGGTVLSNSCGPCIGQWKRSDGVKGRADSIVSSFNRNFPGR
                     NDGISETLSFLASPEVVTAYAITGDLGFDPVNQSVKGADGKEFKLQPPVGEELPAKGF
                     AKGEEGFVAPAEDGSNLTVDIPPTSERLQLLQPFPKWDGKDFEKLPLLIKTKGKTTTD
                     HISPAGPWLKFRGHLDKISDNMFLGANNSFSSEPGKGTNVLTGESNLTMAQIARAYKA
                     KGIGSIVVGDENYGEGSSREHAAMSPRFLNVRAVITKSFARIHETNLKKQGILPLTFA
                     DPKDYEKIEQNDRISVVDLANLAPGKPVTVVIHKTGGDLRIQTNHSMTAQQITWFKAG
                     SALNALN"
     gene            complement(58720..60540)
                     /locus_tag="PK063_02635"
     CDS             complement(58720..60540)
                     /locus_tag="PK063_02635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046912 - acyltransferase activity, acyl
                     groups converted into alkyl on transfer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citrate/2-methylcitrate synthase"
                     /protein_id="HMZ95963.1"
                     /translation="MSILANKDTRVVIQGGQAGVNAARRMAEFCYLIKRPLNVEAFVY
                     PPDAGKTNEIPYGSGLIAIPVYKSIAEATKNHPTLNTSLVYIGADRAMKGGMEALDDS
                     HIKVVSMITEGVPEKDAKILGAHARKLGKVFNGPSSIGIISAGACRLGVIGGAFDNLV
                     LSKLYREGSFGVITKSGGLSNEIIWICSQFADGITTAIGIGGDAYPGTDYVSYLEMFE
                     NDPQTKAVVIVGEMGGDLEERAAEWYGAKKRRVKLIAVVSGFCQESLPKGMKFGHAGA
                     KEGMKGEGSARSKSDALKKAGALVPPTFGALGPAIKETYEDLLKSGQVKAPVEPAVLP
                     RLPKTVEEAMKADEVMVAPLIRTTISDDRGDEPCYDGYPASELINKGYEIPHVIGLLW
                     DKRLISKQEAEIIKRIMMLSADHGPCVSGAYATILAACAGIGLSQSVAAGMIMIGPRF
                     GGAVTDAGRFFKYAVDNKMSVDEFLAYMKKNHGPVPGIGHRVKSLRNPDKRVKELVGY
                     VKSLKIKTPCLDFALEVEKITSVKKDNLILNVDGTMAAVLVDIGFPVDSLNGFFILSR
                     TIGLIGHWVDQKRQDSRLIRLFDYLVNYAAPKRREVPPLK"
     gene            complement(60583..61782)
                     /locus_tag="PK063_02640"
     CDS             complement(60583..61782)
                     /locus_tag="PK063_02640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP citrate lyase citrate-binding
                     domain-containing protein"
                     /protein_id="HMZ95964.1"
                     /translation="MAKVLEGPGMGLMKKWGINVPNYVVVTSVDELTKLGQANEWLKK
                     SKLVAKAHEALGSRFKLGLVKVDLDFKAAEAATKEMIGRQVGSITVTQVIVSEMIPHK
                     EEYYCAVKSTREGSEILVANCGGIEVESNWERVKRLCLDIGQSPSPESLEKLSKEAGF
                     SGALAKKMAEFAGKMFACFDSEDAQYLEVNPVVLRAGDDELVALDAVTLLDGDAKFRH
                     PDWNFAFAAEFGRAYSKQELEVMAVDSKIKGSVKFIEIPGGDTAMLPAGGGASVYYSD
                     AVVARGGKLANYAEYSGDPPDWAVEVLTEKVCSLPGIRNIIVGGAIANFTDVKKTFGG
                     IINGFRKAKSEGKLKNVKIWVRRGGPREKEGLDAMRALKDEGFDINVFDRNTPLTDIV
                     DKALQAK"
     gene            complement(61991..62836)
                     /gene="mutM"
                     /locus_tag="PK063_02645"
     CDS             complement(61991..62836)
                     /gene="mutM"
                     /locus_tag="PK063_02645"
                     /EC_number="3.2.2.23"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: protein motif:HMM:NF002211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003906 - DNA-(apurinic or apyrimidinic
                     site) endonuclease activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-formamidopyrimidine
                     glycosylase/DNA-(apurinic or apyrimidinic site) lyase"
                     /protein_id="HMZ95965.1"
                     /translation="MPELPEAEVAARQLRERVVGALVSDCWVGREDIVREGLSSLEWF
                     RGATITGVERRGKSVILAFIRAAEVKFMTAELGMTGLLLFRNTPTKHPQHTHFVLKLE
                     GGAESEIRYWNPRRFGRLSLLDQAGLDRYTSRRFGPDPLVISQKQFVQLLLSTRSRLK
                     PLLMHQQAIAGIGNIYANEMLFRARLHPDQIANQVNQKAAIRLHEIMGDVLREAIDLG
                     GSSVRDYFAPDGTEGQYKRRHLVYAKSGEPCPNDCGAVIRRSIGERSSFYCPRCQRIR
                     RPQVG"
     gene            complement(63011..63433)
                     /locus_tag="PK063_02650"
     CDS             complement(63011..63433)
                     /locus_tag="PK063_02650"
                     /EC_number="3.1.3.16"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: protein motif:HMM:NF012982.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dual specificity protein phosphatase"
                     /protein_id="HMZ95966.1"
                     /translation="MINKRLLVGNADDAKNPPPQVGAILMVAEEQNVTVPARIIYAKI
                     PLKEFGEPAVSALYDAVQWIEKHLPDNRLMVCCRAGMGRSVSVVIAYLCCVEGMTYSD
                     ALKLALTRRPGGMPLPRLDKVIEDVFRRRCAVERPSLS"
     gene            63566..63925
                     /locus_tag="PK063_02655"
     CDS             63566..63925
                     /locus_tag="PK063_02655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95967.1"
                     /translation="MALIQLEQVEKRLSSVQCAICKTNTFGIDRRTLQSDGECRGVCL
                     KCRYSFPVYTDMEFYLRTQPDIPYRLKEISCPNCQHRGVSLDFRITMSVREAIYFVTC
                     SACHTQFPERSSLEAFE"
     gene            63962..64147
                     /locus_tag="PK063_02660"
     CDS             63962..64147
                     /locus_tag="PK063_02660"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95968.1"
                     /translation="MTDTQKPKPPLPVADVAPKPRKEIPLVSVPNDRDMIAEEMAALF
                     DEDRVSHQHGSSEPEAD"
     gene            complement(64152..65357)
                     /locus_tag="PK063_02665"
     CDS             complement(64152..65357)
                     /locus_tag="PK063_02665"
                     /inference="COORDINATES: protein motif:HMM:NF020804.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="small ribosomal subunit Rsm22 family protein"
                     /protein_id="HMZ95969.1"
                     /translation="MYQLSSAMLGTIATVARVNNSLQNPALSASLVSGVKNLSEMFTR
                     GTKAGATAYLEDGALRASYLHYYVPVNVGKIQMLLEELRPLLPSRTNEEFRVLDVGGG
                     PGTGSLALLDWCSSQSLPPISSLRMTVVDRSIEAMKLSTRLWEEYARQINIPSIQPLQ
                     TAVCDLEHSFPPVLRMGAEKNAYHLIIVQNVLSELFAEKSDCIARRTTLINHLVDCLA
                     KDGSLMLIEPASRAESRALHQVRDNVLSELQCSIYSPCLHDQLCPALLKPDDWCHEER
                     EWQTPSWISQIDREVGFIKDALKFSYVIIRKDGKSLVPRKQDYHRVVSELREMKGEKR
                     VWLCDQTGRSEVGRQDKERSTTNATFDNWHRGAIVRVDEIVRKERKGRPAMVGRILSS
                     GVAEVIRPA"
     gene            65426..65674
                     /locus_tag="PK063_02670"
     CDS             65426..65674
                     /locus_tag="PK063_02670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95970.1"
                     /translation="MTDPILQAYREVEMAMERFTLVLHDHVDYLRKTEAPGSDKLHRM
                     ASGTKAMRDSASIYLSYAKYVAHGMPESPDLVEEDLQG"
     gene            complement(65759..66982)
                     /locus_tag="PK063_02675"
     CDS             complement(65759..66982)
                     /locus_tag="PK063_02675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase C-terminal domain-containing
                     protein"
                     /protein_id="HMZ95971.1"
                     /translation="MTPEYMFLEAPRTKEFITGSEAAKEAIRRSNVDLAIAYPITPQS
                     ETMQLVGVLYGEGYVKEYYRGEEEVGVMAAIAGGSRAGVRCYTATAGPGTLRGLEGIA
                     SWPGHRLPVVAMFTCRVVNAPLAIQPDNIEVSYLLNCGMIVFHAENQQDMYDFTLAGF
                     VISEKNDVTLPVGVCCDGFFVTHARGYVRMQDRGMKLPPREPWRGAVPVLDAENPPAR
                     LSRDAPVQKSNFMAYNIHAVWQQEVWAAVERSRKYINQYMGGLLTAENVEDAEAIIIA
                     SGSAAAQSREAVRICAEKGMKIGLIKVRSLRPFPTQELRKLCGKAKLIVVPEFNYVGW
                     LAKEVATAIYGFSNAKIIGGPRVYGGQSMPVELIVDEVESGLTGKKSTNVAISQVMGA
                     SAADHEAMGHFMRSI"
     gene            complement(67131..67895)
                     /locus_tag="PK063_02680"
     CDS             complement(67131..67895)
                     /locus_tag="PK063_02680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019385 - methanogenesis, from acetate
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon monoxide dehydrogenase beta subunit
                     family protein"
                     /protein_id="HMZ95972.1"
                     /translation="MGTTQDTRERIIVPGPAGFHPPSAAQMGVSLPDPGQGLYYGLLE
                     PNEDTVIEEMARKMLTSPNATIFPGPLVLWAWNNHAVEKAKAVLEIAAQIPDVMIIPM
                     PDYRPKYPKIDPEEVINPNHPNLTIWGNKIEACIFIGVHCHYANLTLKMIRAGTNCCT
                     MAICAEQGHEDAMLTIRDSDTLKLKKTAQIFKKVREELGIKLPDNGENVRFTGTQSKV
                     HDGKTHTNPMTFMPSAAGAGSAAAFGHSPDQMKREG"
     gene            complement(67917..68240)
                     /locus_tag="PK063_02685"
     CDS             complement(67917..68240)
                     /locus_tag="PK063_02685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014450491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95973.1"
                     /translation="MYLVADISVEICAAKSCKLCTQYCPEANTILYSDEMGKDKGFKY
                     GSAYVAVDRCKGCAQCVWVCDNMAKNNAIKMIMIDQLPVAALTDNITYGEKSTTATLV
                     SPVVG"
     gene            complement(68266..68979)
                     /locus_tag="PK063_02690"
     CDS             complement(68266..68979)
                     /locus_tag="PK063_02690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HMZ95974.1"
                     /translation="MATRFNIRMAGVGGQGVVTGSHILSTAVIHAGGESTIVPFYGSE
                     KRMAPVESYVRVSDEPIYEIGEITFPHIIIIFHPQVITHGKSYTMPFYFGLKENGIAL
                     INNDGPMKLHRDQARELEERHAKLYYFPATKLSLEVAGMDLATNMALMGCIGAITGLT
                     TVEALEQSVKDRFLGKGFVVSGGTAALDSVVERKFKKKQELIEKNVAVIRAGWNYAVD
                     HGWAAPSVKRSEATESVTA"
     gene            complement(69003..69902)
                     /locus_tag="PK063_02695"
     CDS             complement(69003..69902)
                     /locus_tag="PK063_02695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HMZ95975.1"
                     /translation="MSLDYVKFSSGFEKFMPKEYRDMVEHGPFGKKVSVSQMGSFKEV
                     LEEHPMCAGCAMTLFIRLAMIAFPNPEDTITVGTAGCGRLAISQAAIPFVYGNYGDQN
                     GVASGLSRGLRLRFGDKPKDVVVMAGDGGTADIGFQQVLHSWFRKERFTTIMLDNEVY
                     GNTGGQESGMTNRGAVLKMAPLGKKFEKMDMLQMAKVAGCAYVATVVPNNPRRVESVI
                     KKAVLIAREVGSTYIQAYTSCNIEYAIPTDKVMEDAKNVENDRYQFSEYITDEAKQFL
                     TERYGYKEFLPKPAAPAPGLPKA"
     gene            70643..71071
                     /gene="queF"
                     /locus_tag="PK063_02700"
     CDS             70643..71071
                     /gene="queF"
                     /locus_tag="PK063_02700"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033739 - preQ1 synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
                     /protein_id="HMZ95976.1"
                     /translation="MREQNKKKLKTGNSTTKLGYNERHARSGISAPLPDIETFPNQYK
                     GYEITIVIPEYTAICPKTNLPDFGTITLHYKPNKQCLELKALKMYVHAYRNIGIFYEN
                     AVNRILQDVVRACRPTWAKVTGEFAARGGLRSVIEAKYPE"
     gene            71378..72679
                     /locus_tag="PK063_02705"
     CDS             71378..72679
                     /locus_tag="PK063_02705"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95977.1"
                     /translation="MSVPTADAIPSFARKYALDCTACHTAPPRLNTFGERFLENGYQL
                     PGTTDGGLTGKKNLGDVSLDDVANYTGVRLRGNVLRTHHFKQQNPSGAEAGTVQNKSD
                     LAFPEVFSLFTAGTLAKNIGFFAELESNLEASHTGIERAFLTFNNIGGENVANIRVGK
                     IDPSAAFSFSTLRQQLDFIAESTHPSTNAVQRAGLFPLATAAKFYGLRNRSGGTISPY
                     APSLYNAVVETGAEVRGRPFGDWFMYQLGVLNGANEGFGDSNKGKDFYGAIRFDYARS
                     ANFSASLSGFAYLGNSNATVFDGTRTTDVNWSRYGVAAHLRYKMFDLHGMYTLDRITH
                     APATALSNFDTDASGLTVALDTHVANNTLLSLRYDTMDAGGDLSQRSSQSFLGAQVKH
                     YVRSNIALYARLDHNLRHAEDGQAAARNLREAFFAGIDVAY"
     gene            72704..73477
                     /locus_tag="PK063_02710"
     CDS             72704..73477
                     /locus_tag="PK063_02710"
                     /inference="COORDINATES: protein motif:HMM:NF012264.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HMZ95978.1"
                     /translation="MGISMYKYLVILAVSGLCATSAYAVRPEDNRDTLAEGRRIYERA
                     CAWCHGNGGLGDGPSGWSIGRYSAPRPRDFTKESYKLRSTPSGELPTDQDLFRTLTQG
                     IPGVMPSYRSLNESERWQVIAYLKSFNPAFEQETPVSIPLPPPPVSRPEGAVQHGRVL
                     YAKYDCRVCHGANGEGNGPESQAGRLRDTNNLPIRATNLTDPASFKNGSTAQDLYRSI
                     MTGLDGTPMPSYANEFAGQEEAVWDLVWYLQSLSGRSEK"
     gene            73558..74277
                     /locus_tag="PK063_02715"
     CDS             73558..74277
                     /locus_tag="PK063_02715"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95979.1"
                     /translation="MVMRLMLVVLGLTLGVPSLLQAESPTGKLAGRITYSGSALPDQT
                     AEITRDSAFCGTSTTIKDVVIHPKTRGLEGVVVSIESGNLPSSDAPLAPLVLTNTHCA
                     FLPRTVIGQVGQQLEIRSDDPVMHNTHISLGSRTFVNVAMIPASRPVRKPLKQPGIYT
                     VKCDAHKFMHADVIAFAHPFFSQTDESGSFQITNLPPGEHVVNIWHHTLGSYQQTVRV
                     SAEAETTIAFDFAAHAESNKK"
     gene            74279..77188
                     /locus_tag="PK063_02720"
     CDS             74279..77188
                     /locus_tag="PK063_02720"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ95980.1"
                     /translation="MPWFHHLWMMWQGSLRLRLSVGMAVLITLGMTVFATIRLVEIRH
                     SLVDAAQARALAVSRTFAMMGAAAVLDNLFRIQEALTRYANEADIVGIVIIDPDNMVV
                     AATKPHDIGRELTDHTLSLAQTSGSETMAHRLSEDGTPTLIVVTPLKNEDDIAAWVRI
                     EFSLAAMQGELVREVRRLLVLSVLLMSVTIVVGQIGIRRMSALFRDTAAKLQDTLHTL
                     HRPLKEDAGNATSLNGDSPGPASYTGELEQMVDLVETTTALLRTQAQRLQSFTDSLED
                     AVRQRTTELHQAKDAAETANQAKSQFLANMSHEIRTPMNGVLGMTELLLTTALTPKQR
                     SLAKTLHQSGTGLLDIINEILDFSKIEAGKLKLECIEFGLRQTVEEAIDLVAETAHRK
                     HLELTCFIPEEIPDAVVGDPVRLRQILLNLVGNAIKFTQAGDVSVTLSLVSQEASRVN
                     LKCCIRDTGVGISDEAKARLFQAFSQADGSTTRRFGGTGLGLAIVKQLAHLMGGDVGV
                     DSIPGQGSTFWFTVSMEYASQAVSAHEGLASPLAGHSILVVDDNSTNRHILEAHLSNW
                     GATVQSAASSEDGLRLLTEAKGGNQKIQMAVLDIRLPGMNGIDLARKIREDVDLRDMA
                     ILALSSEDRETDESHHHPKLFNAWLRKPVHQSLLKDCLTRLCLAPSAEDASATIQPPE
                     QTRTLAGHILLAEDNPVNREVACTMLEILGCTTAVAEQGKEAVETAAHGAFDLILMDC
                     HMPEMDGLTATGLIRAHEQQSMPARHTIIVALTANALEGDRERCLAAGMDDYLTKPFT
                     LDALKELLQRWLPEHVPSDSTSDSQPAEVSNGVPPQQAVSSHAQPLAAESEHVDAHAW
                     EAIRARQRPGQPDFLHKALSLYLPYADKQIARLENAIADQDARAIATIAHTMKSSSGK
                     LGAQRLALLYTELESASRAGRIGDFQELYDRLIPEHRAVSALMRDELNGEGRSAA"
     assembly_gap    77189..77288
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <77289..80236
                     /locus_tag="PK063_02725"
     CDS             <77289..80236
                     /locus_tag="PK063_02725"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ95981.1"
                     /translation="QRLLHSPQPGEAPDAPLESEQVIARQQYESSLRESEEKFRRLFE
                     SSRDAIMILYPPNWNFIACNPATVQLFGARDEAHFTSLGPGDVSPEYQPDGELSMVKA
                     RKAIEAAMREGFHLFEWMHKRVGGPTFLATVQLTRITLQGVEGLQATVRDITEQRRAE
                     TELRAYATFQRAILDHAGSAIISCRPDGIIQLFNPAAEALLGYTADELIGRQHPGIFH
                     VREEIVERARQLSEEFGCTIAPGFDVFIEKSRRNLPNEHEWTYIRKDGTRRTVLLNIT
                     ALRDADSKITGYLAVASDITPLKRTAQELLLAKEAAEAASRTKSQFLANMSHEIRTPM
                     NGVLGMTELLLTTALDTRQRHLTRTIQQSGEALLAIINDILDFSKIEAGKLQLERLDF
                     DLQDTVDNAVELFATPAQRKGLELTCHMPSAIPRTLRGDPIRLRQALLNLISNALKFT
                     STGEINIRIDAVVETDASVTLRFAVKDSGVGIPAEAHQRIFEAFSQADGTTTRRFGGT
                     GLGLTIVKELVSLMQGQIGVESQVGQGSTFWFTAVFERQPATTGDPYPEHALLQRRIL
                     VVDDTAANREILDDHLRSWGAIPALTASAAEALTQLRAAAARQQPFELAILDFQMPDM
                     DGMQLAQAIRADPQLSSLPLLMLTSVGYDAGAPGVPAVDGWVTKPVRKTLLQQAILGL
                     FRTGQRAAIRRPDPVVSEPVTTVSHSARLLLVEDTPVNREVATGMLDVLGYSVHAVEN
                     GRLALEAVAREQFDLILMDCQMPEMDGFTATAAIRQQERQSGGGHRIPVIALTANAMD
                     GDRTRCLAAGMDDYLAKPFTAAQLRTILTHWLTPPVADATTASMPTQTAPPRESTDES
                     PQPTANPEIDKTAWEAIRSLQRPGRPDILAKVLTTYLNDSRILVEEMRAAVEARDPGT
                     LAKAAHRLKSSSAQLGVLATAAHCKELEHLGRLASLNDAAHLLAQLAETHQAACTSIA
                     AELRSRSST"
     gene            80382..82484
                     /locus_tag="PK063_02730"
     CDS             80382..82484
                     /locus_tag="PK063_02730"
                     /inference="COORDINATES: protein motif:HMM:NF012801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HMZ95982.1"
                     /translation="MRCLARTYNWMLPTTTGCLLAATILGTPLTSLAASPIEDAPLVQ
                     TEASLDLPDLPSSGTPDGQEPVGKESTLFEEIPSVYGAAKYDQKVNEAPAAVIIITAD
                     QIKKYGYRNFAQILDSVPGLFTSNDRNYGYLGIRGFNRPGDYTSRVLLLIDNHRLNDA
                     VYDQGGAGTEMPIDVDLIDRVEIIKGPGSALYGTNAFFGVVNVITKRGRDLKGAEVSG
                     EASSFNTYRSRLSYGNKFSNGLEMLLSGSFSDSEGHRQLSYPAFSSINNGIAKDADRD
                     NLYYYTGKLSYGDFTLLGGHQWRKKNVPTASFGTVFNDNRQNTLDERTYLDLVYQHEF
                     VNQLNVKARVYYDRYYYRAHLPYDYAGTGTPPFTLNKDSTEADWWGAELTITKRLFDH
                     HKFTIGSEYRDQFRLNQANADIAPPSTYLDDKRRSSFIAAYMQDEWAITDHLVLTAGL
                     RHDQYSTFGGTTNPRAGLISTWDKTTVKLLYGQAFRAPNPYEQFYVTGSTFKANADIK
                     PERIKTYELVVEQYLGDHLRALGSLYQYNISGLISQTTDPTDGKLFYSNVDNITARGV
                     ELAMEGKWPSGLEGRLSYALQRTENDDLKQQLTNSPQHLAKANVIVPVIADKLFAGFE
                     GRYTSSRLTLAGNSASPFYILNMSLFSQRIVKGWELSGHINNLMNQKYGYPGSGEHVQ
                     DVIDQDGRTFWVKLKYRF"
     gene            82501..83451
                     /locus_tag="PK063_02735"
     CDS             82501..83451
                     /locus_tag="PK063_02735"
                     /inference="COORDINATES: protein motif:HMM:NF016292.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HMZ95983.1"
                     /translation="MRRLIHLIAALGIALTLSALWLIASPDSACAESGRIVVLSGQDL
                     KPYQDVLAGLQQSLTKQGINLAVEIHAAQGAPSTANVLEDIKKNGARLVVTLGSAATQ
                     AAVREVGQVPILATMIVTADDIKSASNATAVLLDFPLDLQMQWLHRIVPAANTVGVLF
                     NPKENQTKVNHALRIAKENGLSLVTQAVDTPRALPDALENLSRHVDALWGISDSVVMT
                     PQTAEPILLSTLRNKVPLAGLSASWVKAGALYALDRDYLDIGNQCGDIAGKILGGTSA
                     SSLAPIFPRKVTYSVNLKTAGAMNLELPQDVVRGATHIFQ"
     gene            83469..86372
                     /locus_tag="PK063_02740"
     CDS             83469..86372
                     /locus_tag="PK063_02740"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ95984.1"
                     /translation="MIKKGIGLRDKLNLLSIGLVVLTAIGIATFVVHREITTRYHDLV
                     NTGLTTAAMIAQNSEYAVYTENQDAVRRAVGGLHALPDIAYAAVLGKERLPILEETWG
                     ANIAIPTALRTRLLAAGDALFEEVAIQQGHPAYIDILVPVVSRPAAAADPLFLESNAS
                     SPPGAVIGYIQLGLSQERLRKNLQEFVLITGLVIGVVLLVGLCMSLILTRSITKPILA
                     LVEAAGHIAEGRLDVDVAAGTHDEVDRLADAFNRMTGRLRTSQSQVQEYQQSLEDKVT
                     QRTKQLELASQEAQRLAEEAQAASRAKSQFLANMSHEIRTPMNGVLGMTELLLSTTLD
                     TRQRHLTKTIQQSGEALLAIINDILDFSKIEAGKLQLEQLDFDVQDTVENAVELFAGP
                     AQRKQIELTCQLMGPFTHALRGDPIRLRQALLNLISNALKFTAKGEINVRVYAVTETN
                     TTVTLRFEVKDSGVGIPAEAHQRIFEAFSQADGTTTRRFGGTGLGLTIVKELVALMQG
                     QIGVESQVGQGSTFWFTAVFERQPAAAPGQEQAPEQALSKKRILVVDDTPANREILYE
                     HLRTWGALPTLAASAQEALVLLGTGSNSPQPFDLAILDLHMPDMDGLELAKAIRMDPR
                     LAGLPLLMLTSVGYDAKTPGTPDLDAWVTKPVRNTLLRQALLGLLHTRHRAPVQPPAP
                     LPSASGPIPFQAAHLLLVEDTPVNREVALGMLDMLGHFAQAVENGRLAVEAVARERFD
                     LVLMDCQMPEMDGFTATATIRQQERDAADHRHVPIIALTANAMEGDRARCLAAGMDDY
                     LAKPFTMAQLSEMLTRWLTLQATAAPMAPGPSPSARQDDSPSDQTPPSAPVEIDRTAW
                     DAILALQRPGRPDILAKVLTAYLNDSRTLVGEIRTAVQTQDAVALAKAAHRLKSSSAQ
                     LGALATAAHCKELENLGRLARLDDAPSLLAQLTDAHQAACAAMTSELLQRPAA"
     gene            86439..87257
                     /locus_tag="PK063_02745"
     CDS             86439..87257
                     /locus_tag="PK063_02745"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008803 -
                     bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="symmetrical bis(5'-nucleosyl)-tetraphosphatase"
                     /protein_id="HMZ95985.1"
                     /translation="MATYAIGDVQGCFSSVTRLTKTIQFDPKQDRLWFVGDLVNRGPD
                     SLKVLRYIRALGQAAITVLGNHDIFLLAVAAGLTSPRPSDTLSAILEAPDCRELMLWL
                     RQQPLLYREGDFLLVHAGLLPAWTVEQAETLASEAHNAIRGDQFLTTLRALHPSGSLQ
                     WRPDLTGPVRVATIIKVLTRLRACSDDGIMESSFSGPPDQTPDGFYPWFDVRGRRSTA
                     ATIVFGHWAAMGLRLTPNMLALDSGCVYGRQLTAVRLEDRKVFQVGCEETRGGK"
     gene            87244..87777
                     /locus_tag="PK063_02750"
     CDS             87244..87777
                     /locus_tag="PK063_02750"
                     /inference="COORDINATES: protein motif:HMM:NF015690.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF309 domain-containing protein"
                     /protein_id="HMZ95986.1"
                     /translation="MAESDQPVLALWPRYTDRPLPAYRFIPGRTPHPRRHPQGHSFEQ
                     PDPLLRPFEPEHWKTSEDYLYGIDLYNWTYWWEAHEVFEAFWHAYGRHTPAGNFFQAL
                     IQCAAANLKRELGHEQATRNLVSRALARLQKCPVHYMGLDTEIIAEQFTQWLNQREPH
                     GHVLFALSKAGGKTRNS"
     gene            complement(87796..88584)
                     /gene="panB"
                     /locus_tag="PK063_02755"
     CDS             complement(87796..88584)
                     /gene="panB"
                     /locus_tag="PK063_02755"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003864 - 3-methyl-2-oxobutanoate
                     hydroxymethyltransferase activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HMZ95987.1"
                     /translation="MTVPDLQKCKRDGRKIAVVTAYDALFARIVEQAGIDVILVGDSL
                     GVVVQGKANTLSVTMDEMLYHTKLVAGAVQRSLVIGDMPFLSYQVNQEEAVRNAGRLL
                     QVGAHAVKLEGGAAMTDRVRAMANVGIPVIGHLGMTPQSVQQYGGYRVQGKGKDRAQQ
                     LLEDARALEEAGAAAIVLEAIPAGLAKTVSEALTIPTIGIGAGPHCDGQVLVLYDLLG
                     LFDEFVPKFVKPYGHLKVEALQALRQYKEDVEKGVFPSDSESYH"
     gene            complement(88584..>88862)
                     /locus_tag="PK063_02760"
     CDS             complement(88584..>88862)
                     /locus_tag="PK063_02760"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0006555 - methionine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HMZ95988.1"
                     /translation="VRPFKVKVLAGILLLRNAKMAEFMNANIPGVCVPQDMIDEMRAA
                     GDKRALDAGVEIAVRTIKAVRPYCDGVHIMAIKSTERLPEILTKAELG"
BASE COUNT        20265 a        26610 c        23010 g        18777 t
ORIGIN      
        1 ggtcgataaa gggaacgtga taggccataa ctacgatctg gtactcgaca caagcacttt
       61 ttccacagtg gacacaatct cttccgcgcc aatgtagtac gcttcttcaa gcgcggcaga
      121 cgtcggcgca ggcgcatccg gcaaacagac gcggccgatg ggcgctttca aagcatgaaa
      181 gacttcccct gccactgagg cggcaatttc cgccgcgatg ccgccactca tccacgcggc
      241 atctgcgatg accaagcggc cggtcttgcc gaccgacgaa tacaccagat tgcgatccca
      301 gggtttaatc gaacgcacat cgatcaattc cacatcaatg ccccgctggg tcaacgtctc
      361 aacggccttg gtggcttctt tcgacatgta tgacgtggcg agcaccgtca catcccttcc
      421 actccgtcga agcgccgcgg agcctatggg cacctcatac agaccttcag gcacatcccc
      481 ctgcagatcg tagagccatc gatcgtcgat gtagagcacg ggattgccgt cccggacggc
      541 cgcgatgagc agccccttcg catcataggg agtggccggc atgacgacct tcagcccggg
      601 cacatgcgca aagagggcct gcagagcctg agcatgttgc gcgccctgtt cgccccctcg
      661 attaatcact gctcgtatca cgatcggcac ggacacccgg ccggcgaaga gatacgacca
      721 attagccgcc tggttcatga tggggtccat cgccagcaac ataaaatcca tgcgcggatg
      781 aaacacaatc gggcgcatcc cggtgatagc agcgccgatc gccgccccgg tcgtggcatt
      841 ctccgacacg ggcgaatcaa tcacgcgatg ggtcccgaat tccttgtcca gatcctgcag
      901 gctggttccc gcataccagg gattgcgaac gccctgtcca atcaagaaca cccgtgggtc
      961 ctctgcgagg agttgggcgt gagcctctcg aatggcctgc gcatacgtga gtatccgcat
     1021 acgcctagac tcccccccgc gcgtaaacat gctgtagtaa ttcgctttca tccggggccg
     1081 gcgatagccg tgcaaagctc acggcctcgt caatttccct tctgatctcg gcctccagcc
     1141 gatcaaagac ttctgacgac aaaccatgta ccttcagcaa gccacggcac tgcgcgatcg
     1201 gatcgcggcg ctgccagtca tcaagttcgc gccgtcggtc cgtaccaacc tcgagatcgg
     1261 ccgcaggccc cacatgtccg cgccaccgat acgtgcgaca ctccagcagc gtggggccct
     1321 cgccaattct cgcgcgctgc acggcctgat gcgccgtctg atagaccgcc gtcgcatcgt
     1381 tcccgtccac caccacgccg ggcaatccat gcagcgctgc gctctccacg atattgtcct
     1441 ttacccgtcg ctctttcagc gtcagatgcg tggagtacaa attattttca catacgaaca
     1501 agactggaag acggtacaag gctgccagat tgagcgactc gtggaagtgc ccctcgtcgg
     1561 tcgcaccatc tccgaaaaaa gccacggcca cctgctgcgt tcctcgcaat ttggccgaaa
     1621 gcgcggcacc aacggccagc ggaatggtgg ccgccaccaa cggaaccgtg ccaaagatgc
     1681 cctgggccgg atccaccaga tgcatggaac ctccacgtcc gcgcgcgcaa cctgtagctt
     1741 tgccaaagat ctccgccatc atgccgcgca gatcgccgcc cttcgcaaga tagtgcccat
     1801 gggaccgatg cccgccccac agagtgtcgt cttgctgcaa cgccgcgcag acaccggcgg
     1861 gaattgcttc ctgcccgatc gagagatggc acggtgtccg cacttcgcga gtttcgacga
     1921 gttccccaat gcgctcttca gccatgcgga tgcgctgcat ggctcgaagc aacgatatga
     1981 gttggtctcg cgacaacgca cctgtatgca catccgggaa gttcatgcac ctaactccag
     2041 cactcgtggt tcgcggaatt tcacacggaa cagaaccgct ccaacggtcc ggagcagaat
     2101 atcgagatcg gtccggaagc cggcctggcg cacatacgcg agttgaaggc ggattttctt
     2161 cggtctgatg agctcacaat aggttcgatc aggatcagca ctcccctcaa gaatggctcc
     2221 ctcatcgatg ttccagagac tcgcccaatc ggtgagaccg ggccgcactg cgagaatggc
     2281 tttttcttcg tctgtgtaca aatccacaaa tcgctgcact tccggccggg gcccgacaag
     2341 actcatttcg ccacagagca cattccagag ttgcgggagt tcgtccaatt tatatcgtct
     2401 taacaccgcc ccgacgctcg tcacccgagg atcgtccttg gctgttgagg tcacgccgga
     2461 ccgttcggca tccgatctca tcgtgcggaa tttcaaaata cggaatggcc gcccgtttct
     2521 ccccacacgc aacccacgat aaaacggtga gcccccatcg cccaatgtga tcaacagtgc
     2581 aatcactacc agcatgggag aaagcagcat tagccccagg accgcacaaa gaacatcaaa
     2641 tactcgtttc ataatagaaa agacgctacc gcccactgct tcagtgtcaa gaatcgatca
     2701 accagaatcc tgctacacgc gcatgctcag taacgtgcca gtatggcggc tgagatggta
     2761 ccgcttcaag agtgtttttc aggcccaacg cgctctcctc atgatttgcc cactgcaaac
     2821 cgagccatcc atgatcgcca cttgtacccc acacgctgag cagaactgca ttcggggcca
     2881 gaagtgcctt gagaacggaa taatcaacgg aagatgttga aaggaagcgc tacctgcgtg
     2941 gcaaggtaca agaattgccc gacctgtatt tccgaaacat gatggaatcc agaaaaactt
     3001 cctccacgtc tgttttatct ggcgggggcg gcacggtttg tctccacatt gaatattttc
     3061 tgccaaaatt cacggattgt aagaagcctg accacccccc agagggagcc gagcccgtat
     3121 ccgacatgca acatcgcaaa aattatcggc atcagcactg cgtattgtgg ttgccttgcc
     3181 tcccaggcga catggagtga tgccaccaca ttcgcgagca gataggcgcc gagaatgccc
     3241 gcaaacatcc atccgaacgt cccctgccac gcggttaaga cgagcgtaga taccaaacta
     3301 ccgacaaaaa acagtggaac gaggtgacgt aggctaaccg gaatcacatt gctatacgcg
     3361 aagggcaaaa tagcccaaac gccattgatc caattgtgac accagaagga cttgatgtct
     3421 gaccgagcgt aatagtaact gacgatatca ggtatcagaa gggtgcggcc tccggccttc
     3481 cgcaaacgaa gactgaattc catgtcttgc cctcgcgtca gccgctcatt gaacacgccc
     3541 ggttgattca accgaaggct aaactccatg tcttcgcccc ggaccaggct ttcattaaat
     3601 ccaccgagtt cctgaaatac ccatcgtcgc acgcaaaaga acggaaccgt atcgacaaac
     3661 ttcggctcgc taccttgggg cagccgaaaa tgagaattgc caaccccgaa tggatgggac
     3721 agagccttaa cgacgcccca tcccgccaat gtctccgttc gaggcagcgt tttccaaatt
     3781 cctcccacat tgtcgacttt gtactttccc agagcatcca cgcagcggga gatgtaatgg
     3841 ctgtcatatc gagcatgggc gtccatccgc atcacaatgg ggccacgggt gtgtttaatc
     3901 ccgaggttca aggcagcggg agtcacacgt ttggggttgt ccagcaccga aaggaacgca
     3961 tggtcacggg aaaagccgtc aagaatttca cgcgtgccat catcgctcag gccgtcaacc
     4021 acgagtattt ccaagcgatc tttgggaaaa tcatttgcga gcacggattc gaggcagcca
     4081 gcgatgaacg ccctctcatt tcggcaggga atgataatcg agacgatagg gtatgtgtga
     4141 aaaaacggac cagagaccca tggcgtttca gcctgtgagt tagtgaaact catgcgcgtg
     4201 caccaatcag ttcctatggc ctagtttgga ggagccgccg cttcccgata ccgataaagc
     4261 gatcgattga cccgaaactc ctctaggcgc ttcaccaaca tttcaccgac tagtttgtgg
     4321 ccctcttcac tccaatgggc gccgtcagca tgaaacacat ctcttccttg acgcgccgca
     4381 aagtcgaccg cctcggcaat ctcatcgaga aagatgatgt catgtcggcc tgaaatattc
     4441 ttcagtgcag cattataggg ctctaccgct ttgcaattga aggccactac tggcgtggct
     4501 ccaacacgag ctctcacagt tgccatcaat tcatccgttg tacgaaccgc cctgcgaaaa
     4561 tctggatgct gcgccccgga tcgcaagatt tcagcctcta cgctatcgag cagataggcc
     4621 gcatagagcc gatccattcg gctcaacaaa aaaacaataa accgtgaata cttataagcg
     4681 agcccccgaa atttccccag aatagaactc ggcatgtcac gtatgatttc ccccttgctc
     4741 caatacgggc gttgacgaaa atctatatgg agcatcgtgc gacgctccat caggggatca
     4801 ttattcgcga aatcgttgta gcaatattgc cacacaagca gatccggctt gatgagatca
     4861 aaaaaccgat ccaggatcat atactcttgc agagtgccat agttttccac tccatacgca
     4921 aatacttcgt aaggacgttc gcgtccaagc aaagcatagt aagtcttcga atcagaaact
     4981 tctcgcgcat gcgtaaatga atcgccaagt atcaatatct taaatttgtc cgacccaatc
     5041 tcaccaaatt ggcgaaaccc atagcggttc tgcgacagcg tcacaacata cgacttgcct
     5101 tgcttagttt tttccgccct gttcgcgcgg tagttttcag tagccttcca gccgagtgtc
     5161 tcgtccaaca tcgtgccatc gaaattcccc agaaaaaaac ggtgccattc gcgagcagga
     5221 attccatctt tcgtccaata gtaaactcgg aacacggctt caccacacaa tatggcgaaa
     5281 caaattgaga cgaggggaag gaggcacgtc gcgatagact taagtagctg gacatgtcgc
     5341 gaagtcattg cgattgggat tgatggcggc taagtctcaa ccgtgatgaa tctagacttg
     5401 aatctgggcg cacttctttt gccataagca cgatgtagag tccgaaagaa atcagggcca
     5461 atgttgtact tgtataggtg aaaaggctga aactaaaact aatcatgacc gcagcatata
     5521 ctgctgtcag aaaaggaacc gcgactacct tgcctctcaa cacttggtgg tatgaatgtc
     5581 cggcgatata accaaaaatt aaagccgaga ccagagcacc gatgtggcca aaatcatcga
     5641 tcaatccttg aaacaccgta taaacgttcg agctcgtgta gccaacgtca acggcttcat
     5701 atatgtagtg atcctctgtg cctaatctgg caaactcgaa gatgcgcccg aatgtgcgat
     5761 ctccatatgt cagatcagaa aaactaaaag tccccttatc gagcaagatc gcaaatgagg
     5821 gaagaaacga aaagatatct gaagcggcca ggagcaacaa cgatagtgtt gagacttctt
     5881 catcaccata acgaagggag agtaccacta gggacgtccc cactattgcc accgcaatac
     5941 agatgagtgc tcttaaattg ctcacatcac tatgcgcctt tccactccga cctcccagca
     6001 acctggctgc catatatgcc gaaatccaga acgcacctcc gaacatggcc cccatacgcg
     6061 agccatagag caaattgtgc gccgcagggg cgatgacagc aaggacggcg atagccttgt
     6121 ccatattcga gacagcaacc tgaaacagaa ttcccccaaa caacggagcc gcatagaatg
     6181 cgacaaataa tactctttct atgaacgtga gcttctccga tccatacaca aaggtcgccc
     6241 gattttgcat cactatctgg ctgaggttct ccacagaaag cgcctccccc aggctgggac
     6301 tcccatccag aataatgtag ctgattctca ctaaaccgat aaaaaccaga gtgcccgtga
     6361 cggcacgtaa atatggatat atgaatcgct tgtcttcgca ctgattttca acgcgctgcg
     6421 atcctgttcc ccagaggcat ccaagatgca tcaaaacgcc ggaaccagcg atccatacga
     6481 ttccgagaat aagggtttcg gaaggcacgc ggaataacaa cgcggtgaga ctgtaccaac
     6541 tccaaagcag cgcgaataaa gcgccggggg ataaccaact gccctccgca attcgggcaa
     6601 tcaatgcaat acaggctaat atcaagactc cttgcacaaa taagaacatc tgtcttacct
     6661 aacgaacatt ttgacggtca tccagacaca tgagaacttt cagtacttca gccgcgtcta
     6721 tcgagcgcat acattcttga ccatgcggac atttgccata gagcacggtc tggtagcatg
     6781 gcatacagtc cggacgtttt tctgtctgca caacacgatg cttgttgccc cagggacggg
     6841 tattaacgat gtcggtcggc cctgcgacag tcacgacagg cgttccaacg gctgcagcta
     6901 tatgccccaa acctgtgtct ccagaaagaa ccgcctgaca cttgccaatg gttgctgcca
     6961 cgaccgtcaa ccgcaaccca gacagaatga tcactcgctc aaggccccag tcatacgatt
     7021 tgatgagacc ggtctcatca gggccgaaaa acaaaacgac tctccgggtc tcatctcttg
     7081 ctagatattc ctgcacaacc tctcgacaaa gttcttgtgg aatctgtttg tccggacatt
     7141 cactgccttg accaccagga tggacgccca gtacgtcgca tgtatctagg tgatgattcg
     7201 tccaaatcct ggccgcctca gttcgagctt gttcatcgaa ctcaaagtgt agatccccaa
     7261 ttccacaatt cggtaatgcg agcttgagaa tctccgcatt ttccatcacc ctgtgattcg
     7321 tattgtcgac tcgacgccaa tgggtatatc cccacccttt tgcgccaccc ccatcaccga
     7381 caacggtcct tacccctgag agaaatttca gcccaagcgc gatcttcggt gacagcccgc
     7441 ttgcgatgaa tgctacatcg aattgctgca tgcgaaggcg aacaaagaac cgcagaatcg
     7501 taaacatcga actgcgtcga aacgacatga cttgcacttc ctcacacaac ctcgaacctc
     7561 ggatgacctc agctgctgaa tctgacccgg ccactacaca gatatgtgcg gacggttgcg
     7621 ctagacgcag tgcatgaacc atgggcgtgg tcatcaccat atccccgatt ccccatgtct
     7681 gaacgacaag aatcttcttc attgaacgtt atcgcacaat cgcaacattc cacattgacc
     7741 taaccggccg cactagccac caggtcaaca agccatacga gcagatgtac agcacaccgc
     7801 ccccagttgc ctgccatcca tggtccacag gcatcaccag aaacgatgtc gtggcgaaca
     7861 gagcgcaagt agcgcacttc atggaaaacc aagccagatc cttccaaata ggagagttca
     7921 gtcgccagcc aagactgatg acttgcatgg cgctatctac agcgaacgcg agtgcaagac
     7981 tcagtgcaac gccagctaaa cccaacgccg gagtcaacat tagacacaat ggcacgacta
     8041 aacaggcgct tagaatcgtt gcaagcagcg gcgaccgggc atctcccgct gcatacaggg
     8101 cccgagtacc aaccggttcc caggctccaa aggtgaggcc tattgcaaga aacccaaaag
     8161 ccgtcgccgt gagcgtaagc gctgcctcat cgaatgcacc ccgttggtag agcaatcgca
     8221 agagaggttt ttgatatacc caacacaaca ctgagagcgg aagaaatcca tacaggatta
     8281 atctggccag ccctgcaaca aactctctga attgctcttc tcgaccgtac gtaaacaggg
     8341 aggcgaaggt agggtatgca gcccgcgcca cactcaccgt aatgagcgaa atcagtcccg
     8401 cgacgatggt gcgtgcatag ctaaatgccg cgatgctgcc ttctcccaag ccagaggcaa
     8461 agtagtttgc caatagcccc gggaactgag aggcgacgta gtacaaggca acaggcaggc
     8521 aggccaatat tggatgtacc aatcctgtaa aggacagcgc accaaagtgt gcgccatgcg
     8581 ttctcagaat gatacccatc agcacgagga ggcaaatgaa aatgcccccc agattcccga
     8641 tgacgagggc atgcacaccc acgttagagg ctagtgccat gagaacccca attacgacga
     8701 cattgaagag caaatcactc acggccggca atcgaaaatg gttgaacgca tgaaatacgg
     8761 cagataaaac atagacacaa ttctgaataa gtacgtaaat cgagagccac cccataagct
     8821 cgacagtgag tcttatcgtt gcggcagaca ttgatggtgc ggcgaactta actaaatact
     8881 caggtgctcc ccagaccgga ctcagcaaaa tgaaagacca cgccacggat gagacgcaac
     8941 tcgtactcaa atagtgaaga cccgcctgct tcccatgctc cgccaccatg gagtggtacc
     9001 ctgggataat ggcagtagaa aaggcataac caatcccgcc cgcgagaaaa aggggaatag
     9061 cataggcaac agcataggca tcgatctctc tgccagcccc aaagtagctg gccagcaaga
     9121 gttcccgcac aaaacccaaa accttgctga ttccggtcac cccaaacagg agtgctgaag
     9181 ctgaagtcca agtctgaacc gaaagcgctg ttcgtgactc atgtcccata ctcatctgtg
     9241 gagtccctac gaattacatg gcgaaaccta acttgggaca taccgattga agctgcttat
     9301 attgattgat tgacgccacg cctgccaaat tcttatcatc ggcccccacg cgtgaaacca
     9361 ctgctctccc atcgctttcc catcagccca ctatggtcag ggctgcttct cgcgctgctc
     9421 tacctgaatg tccacgacgt gcttcgagct gaggaatctg cctcccccac cacctcccac
     9481 gtcgtcgaca tgcggttctc cacgacgacg tttctactca atcttgaaaa acggggactg
     9541 gaggataata ccttcaccaa cggcctggga cgcgacacga cgttgatcgg gaacctgatc
     9601 aacgcgacgc tctacaaacg tctacttccc tcgctagagg ccgaaatcgg cgtctttgcc
     9661 aacatgccct ttggacacga tcacgaaatc tcacaggtcc gtcccgtcgt ccgcctgacc
     9721 tatcaaccgg tcgagcaaat cacagcagtc gccggcacga ttcgcacccc gcaccgggac
     9781 ttccacgacg cagtgtttga caacggcaac cggttcctgc gcccgattga acagggggct
     9841 caaatgctag tggattccac ccactatcag caagacctgt tcatcaactg ggagcaggcc
     9901 tttcgtgggt cggcccccaa tcgatacgat gtcgggtatg ccgggcaact gaagttcggc
     9961 cctttgcatt tcaatggtca ggcccattgg gtgcgcaacg ggcaggcact gttcaagcta
    10021 gaccgatcgt tttcgacacg cgacaatctc gtcgtcgcca cgggtccaga attggtgctt
    10081 gaaccatccc gatggttcgc atctactgct tggtggcatc agattggtat cagtttcacc
    10141 tacctgacta gctacaacca ggccgacaat ggctcagacg cgtcgcgcgg gcggggttat
    10201 gaattacgca cctggctcga cttggccgga tggcgtccct acctcgcctt ttggaagggc
    10261 cggaacttcc tcagccaaca gggagacccg gaatttagag cgagcaattt cccggaattc
    10321 gggctctcga aaacgatccg tctcggcaag cgcgcctcca tcgaattcgg agcgcaagcg
    10381 cgccgtatcc gagccttctt caccgaagac ggcctcaact atatgaacag ggatacgttt
    10441 aagtgggtga atcaggaata tctcgtcttc aattgggatt gggataccaa ccacgccgac
    10501 ctgattggtg atgtatgggc ttcgctgtct cggccttttg atgatcgaca ggacgctccg
    10561 tcagagcgca ggttcacagc caaactcgat acactgacct atgtttacag tatctcctat
    10621 cacggggtac ggcagatcgg cggcatcccg gtctcaaatc acacgttcgc gggacaatat
    10681 ctctcgccgg tacttcaata tcgagtcagc ccccaactca cactcgacgc cggcctgttc
    10741 gccggattgc ccgttggaga tacacagtcc tttcacaccg tgcaaccgat tctctccgca
    10801 caatatgaaa tggtgccgga tgtgcgactg gtggccggaa ccctgcatcg caaccatcct
    10861 ttcgtggacg cattattcaa tgatgccacg ctgttcagcc gccccgtgga acaaggcttc
    10921 caattgctgg ttgatcgtga acattaccag caggatctct tcatcaactg gaaccagatc
    10981 gaaacgtatc agaaggcaga gcggttcgac gtgggctatg caggtcgagt agcagcaggg
    11041 cccttcgcgc tgaatggcca ggtatattgg acccatttcg gtggcgccca atattcagaa
    11101 gcccgcacgt ttttcggccc tggactgccc cgcgaccgcc ccgccggcaa caatttcctc
    11161 acggcgttcg gtcctcaatt cacctggcag cctaagcagt actggccgca gttgtcgtgg
    11221 tttcgggaaa tcgatgtcat ggccctgtat ctgaccagtc agaacgaacc gacgcagagc
    11281 agttcaccaa tcgttcgtgg gcgcgggtat caactgacag caggcgtgaa cttggacggg
    11341 tggcggccct atatcacgct ctggcgcggg gaacactttg tcaccgagcg gggcgaccca
    11401 gcctactatg cgggtgactt cacagaattt ggcctgttca aagatttcat cctacccgcc
    11461 ggcttttctt tacgactcgg cggattcggc cgaacgatcg aacggcatct cacccatacg
    11521 gagtacgcgc tgttgaattg gtcgtgggat caaacgccct ggcgcggttt ctgtcaacgc
    11581 cccacgctgc tacaccgaag tgagtcatca tgcggtcaat cttgagatac acttctctct
    11641 tgccaccccg cgccaagctc gttagagtag cactttagtg ctcctgaggc cgtcagctat
    11701 tgtaagagga gggcgcatgc gccgttcgtc aatcggtctt ctgtttctgg ccctgttgtg
    11761 cattccagcc gtcacacgcg ccgagaacta tgtggctgcg gggatcggcg tgaatgctcc
    11821 cagttttgat accacggatg ccggcaaagt ctctctacag aaggatctgt tttatggagg
    11881 caaaatcggt cactacttta atgaccgggg ctataattgg tttggccttg aagtagacat
    11941 gtaccggtcc acgcccggca tcaagcaaca gaccctcccg acctccagca atccacgact
    12001 gtcggggcca atgccgggcg ctgatttgca ggtgcattcg ttggccttta atgcactagt
    12061 ccgagtcacc ggctatcagt acaaagtgga gccctatgcc ggtcttggca ttggcctgaa
    12121 cgtaggcaat atttccaacg gcaacttccg acctgaagca tccttcgctc caagctttaa
    12181 tgtcctcgcc ggtatccgtt actacatgac tgagtcaatt gcccctttca ttgagtacaa
    12241 gtataacttt gctcaattca agttcgaccg cagcaatgtc acggcagact atcgagccaa
    12301 tctgtttatg ttcggcattg cctaccattt cggacggtaa cccctgccgg atccagcgtc
    12361 ctgttcttac gaggacgacc tcttctttcc atccgatggt ccgccaacga tcgtgagaac
    12421 agtcagcact attctccgtc ggcatcggac gcgcggaagt gttgcccgga cttgatatag
    12481 gcaagaatgt cgggcttcgg caccttcaac gcctgaaatg catgccgaat cagggtatgt
    12541 gccccttcga tttctggcag gatgatttct gtcgcgccta ccgccctcaa atcttctgcc
    12601 tccctaaatc catgcgcccg gacaagcacg gggatttttt cattcagtcc ccgcagccgt
    12661 cgaacagtca gcgatgcttc gtgaatcacc gggagcgcaa caatcaccag agcagcccgc
    12721 tcagcgccgg ctgcagtcaa cagctcggtt tgcgaggcat cgccatacac gcaggaaatg
    12781 ccgcgacgcc gtaattgtcg tacgaggtcc gggtcgcgct cgatcaccgt gtaggcgatc
    12841 ccaaaatggt caagggccag gcccaccgtg ctgcccatgc gaccgaatcc gcacaccacc
    12901 acgtgccctg cttgctcgtc ttggacgccc ccttgcattg gcatggcagc ccgtcccatt
    12961 cgcaagtgca aggccgcgac ccacctcggt gcatatcgaa cgaacggtgc gttgagaaga
    13021 atgctcaaca acgatgcggc gagggtggca ttatacacgt cctctcccac atgacctgcc
    13081 gtcttggcga cctgcaccaa cacaaaagaa aactcgccga tctgcgtgag accgacgccg
    13141 acgaggagtg cggtgcccca ggcgtaacgg aaaagtcgta caaccagggt ccagatgacg
    13201 aacttgccga tgagaatcaa tccgagcatg aggccgagca gcggaagatt ggaccacacg
    13261 atacgcgggt cgatcagaat cccgatcgtc acaaaaaaga gggcgacgaa tgcatcgcga
    13321 agtgagagca gcctggcaag cgtttcgtgc ccgtactccg acccgcttat gatcaaccca
    13381 gccagaaatg cgccaagggc aagggacaat cccgccatct gtgttaccgc cgccgtcccg
    13441 atgcccagag atagcgagac caggagaaag agctcggcat tttgtgtctt cgcaatgcgc
    13501 gtcaataacg gagggatcgc tttggccgcg agataggaaa acggaaccag aattagaact
    13561 gccaaccata acgcctttcc aatggtagcg aagcgacccg gttccagcgt gcccagcgct
    13621 ggaagcagca cggtgaggac cacgacggcc agatcctcca ccaatgtgat tccgatcatg
    13681 accctgccat gtttggcccg taagtcgccg ctatccagaa gcaaccgcgc caacaccatc
    13741 gtactggcca cggagaccac cgacccaatc accacgcttt ggatcatggt ccatcccacc
    13801 agatggccga gcccgacgga gagaagaatg gagaggaaaa tcccgagtgg tcctcccagg
    13861 agggcgaccc aacgaactcg caacaagtca ttcaacgaaa attcgatacc aatgctgaac
    13921 atcaacaaaa tcacgccgat ctcggcgaac aattcaaagc tgtggacatc tgagatggat
    13981 gggccaggcg tcaagggact gatgagaatg ccgccgaaga catatcccag aatcaatggc
    14041 tggcgaagca gataggcgga agtccctccg acgaccgcag cgatgaacac ataggcgaga
    14101 tctcgaaaaa aaattggatc aggggtcatg catcctttca gacaacaaat tcgtcatccg
    14161 caaattggtc tgagcatcaa acaggccttc cgtattctaa ccatttcaca attcaggagg
    14221 taaggttctt gatccaaaag ggcacggctt tggcttctca cgcacgcgcc aacaatgaca
    14281 tcgacagcct caagtttttc tcttttgcgc ccgaccgaac agccctcttg ccttacacta
    14341 tccagtgtca aatgctgaca tccgaacggt gcagtaactc atgggccatt ccaagagcgc
    14401 catgacgagg cattacgccc atctcctccc cgactcattt acgaagaacg atgaatcgag
    14461 cgaatgtggg tttgcagcaa aaagtgtgaa tggactcggg agtaaaaccg ggagtaacga
    14521 aactcagcgg gtggaacagg ggccggttag aaccaccgaa ccctctgaga tgtctgtagg
    14581 aatggttgga ggcgccgggc gggttcgaac cgccgcatcg cagttttgca gactgctccc
    14641 ttagccactt gggtacggcg ccacgggtcg gattatagaa gggggaggtt caggaactca
    14701 accgcgaaga gcagagaaac agaggaaact cccacaacac agccgctgaa cgaatgccgc
    14761 ggattacggc ttactgggaa gcactggaat gtcgcgaacg atggtggatt gttcatccgg
    14821 cgcatggccc atcaattccc aaccttcttc ggtctgtccg tccgacgacc cgttgtgcgt
    14881 gacaccggaa gcttcagcct ctttttcttt agccagctgt tcgacttcgt gaatgagggt
    14941 gtccatgagt tcatccatgg gcacctttcg catcaacttt cccttcttga agagaatgcc
    15001 tttgccttct ccgccggcaa ttccgatatc cgcttccttg ccttcgccaa tgccattgac
    15061 cacgcaaccg aggacagaca cgttcaacgg ggtcttgata tgtccaagct ttttttccaa
    15121 ctcgttcgcc atacgcacca catcgatttc gacacggccg caggtgggac aggcgatgac
    15181 attgatcccg cgatgacgca attccagcga cttcaggatt tcgaagccga ccttgacctc
    15241 ttccactgga tcggccgcaa gcgagacgcg tagcgtgtca ccgatgcctt gcgaaagcag
    15301 ccacccgagg ccgatcgcgg acttcaccgc accggtcatg gccgtcccgg cttccgtaat
    15361 accgatatgc agtggatagt tggattgagt agagaacaga tagtaggcat cgatcgcgtg
    15421 gtgcacatcg gaagccttga gcgacacctt catgttggtg aagccttcgt cttcgagcgc
    15481 atgcacggcg ttcaaggccg attcagacag ggcttcaggc gaaggccagc catacttatc
    15541 gagcaacggc cgttcgagcg agccgccgtt gacgcccacg cgcaggggaa tgccccgctc
    15601 gttgacggcc ttgatgacgt cctgcacttt ccaccaggcc ccaatgttac cggggttgat
    15661 acggacgcaa tcgacgactt cggccgcttt gagcgccaat cgatgatcaa agtgaatgtc
    15721 ggcaattaac ggcaccgaca tggccgcctt gatcttcggc agcgcgttcg ccgcttcgtc
    15781 gtcgggaacg gcgacgcgaa tgagctcaca cccggcggtt tccaattgcc ggatctgctc
    15841 cacggtcgcc ttcacatcgc gcgtatcggt cgagcacatc gactggactg aaatcggcgc
    15901 atcaccgccg atcttgaccg atcccgcttg aatctgccgc gtctttttcc tggtgatatg
    15961 catgggtgtc agcggcctta gctgccttgc tcatcaccgt gcggcaggct gccgacgagt
    16021 gaagccaggc gagcggcatc gtccgccacg acaccggcgc cgaacaactg cttgacgctg
    16081 ttgtaaatgc cgtcggcggt gagaccatac cgctcacgca acaggtcctg cggcccttgc
    16141 tcgatatacc aatccggcaa cccaaggatc ttcgtgcgca gcatgactcc ggcttcggac
    16201 aatgtttcca agactgcgga accgaatccg cccatcttac aaccttcttc caccgtcacc
    16261 agacaacgga cgttcttcgc cgttttgagg atgagctcag tatccagcgg tttggcgaag
    16321 cgggcgttga cgacggcagc ggaaatgcct tcctgcgcca accgttcggc agccttcatg
    16381 gccggccaga ccgtcacgcc gatcgccacg atcgccacat ccgttccttc acgcaataac
    16441 tctcccttgc cgatcggcag agtggttggc tcaggatcca tcggcacacc caggctgacg
    16501 ccacgtgcgt agcgcacgga agcagggcca tcaaaactca cacaggtctt gatcatgtgc
    16561 tgcaattcgt tctcgtcctt cggtgcggcc acgaccatgt tcggcacatg ccggaggaac
    16621 gcgaaatcaa aggcgccatg gtgcgtcgtg ccgtcttcgg ccacgagccc accacggtcg
    16681 atgcagaacg tcaccggcaa attctgggtg gccacatcat ggacgacctg atcgtaggcc
    16741 cgctgcagga aggtggaata caaggcaacc accggcttca tgccctgcgc cgccataccg
    16801 gcggcaaagg tcacggcatg ttgctcagca atccccacgt catagatgcg ttccgggaac
    16861 tctttttcga acgcattgag ccccgtgccc tcacacatgg ccgcagtgat cgcaaccacc
    16921 cgcttgtcct gacgcgcaac cttgatcaag gcatcgacgg ccatgctggt gtaactggga
    16981 cgcacggctt tctttgccgg cacccccgtt tcacgcacaa acggcgggca ggcatggaac
    17041 cacacggggt tatccatggc agcctgatat cccaagcctt ttttcgtgat cacgtgcagc
    17101 agaaccgggc ccttcatttt cagcacattt tccaatgttg gaagcaggtg ctcaaagtta
    17161 tgtccgtcga tcggtccggc atactggaag cccaactcct cgaacaacag gccgggaaga
    17221 atcgcaccct tggccaactc ttcggcccga cgagcgattt tttgcatttc ggcaccgatg
    17281 tggggaatct tccgcaggag ctggccggtt tcttcacgca tcctggcgta gaattcaccg
    17341 gtgaaggtcc gattcaagta ggcggaaata gctccgacgt tgcgggaaat cgacatctga
    17401 ttgtcgttga ggacgacaat aaaatccttg ttcgtcccgc ccgcgtgatg caaaccttcc
    17461 agcgtcatgc ccgccgtcat cgccccgtcg ccgacgacgc agacgacctt atgtttttct
    17521 ccccgctgct cgcgggcttc caccatgcca aatgcggccg acacacccgt accggcatga
    17581 ccggcattga aggtatcgta cgcactttct tcacgcttgc agaacccact caatccgccg
    17641 tattgccgca atgtgtggaa ctgttcccga cgcccggtga ggagtttgtg ggtgtaggcc
    17701 tgattgctgg tgtcccagac gatcttatct ttcggcgtgt ccaagagata ttgcaatgcg
    17761 accgtcaact ccacgacacc cagattggag gccagatgcc ccccgacatt cgaaaccacc
    17821 gcgaggattt gctcacgaat ctcctggcat agttccggaa actgttcagg ggacagtcgc
    17881 ttcaaatcag cgggactgtg gatatttttt agcagagaca ttgcacaatc tccttgtcaa
    17941 agcatgacaa ttggacgcag gtattcatat tcgtggaaaa caatcgtctt gagaaggtcg
    18001 tggcgaagca gcgaaagaag ttcgtacaaa tcgcctcatc ctcacatatg gcaacgcctg
    18061 tgtcaagatt ccgctgtcct ccggaccatc cgaccatcgc cttacgaccg aaaccggtac
    18121 gtaagaaccg tagaaagggt aaaatcggcg gcgctgccgg tgatgaagtc caggttttcg
    18181 actccataga cttgccacag cagcctcggc agtatccggt aacttacccc cagaaccgac
    18241 tcggtcaccc ctttatccaa aacacgggtt cctgtgccgt gaaacggggg ggaataatag
    18301 tcgaactgcg ccgtgatgga aaaattctcc gtccagaggt attccaccgc gaccaacccg
    18361 ctgacgaccg gttgcacatc aagtcccgcg atccgtcctg tgggaaagat tccgttcacg
    18421 ttggcgtaca ggatccagcc ggtcgcgaaa gtcttgtcga gggccagacc gatgccggca
    18481 tccgggtggc cgcttccgaa tacctgtccg gtgtctcccg tgggagcttt gaccgccata
    18541 cggatcgaca atgccggctg gcttccggtc tcttgcaaca actggtattt gccataaaat
    18601 gagacatcgc ctaagccggt ggcattttcc gatccctgga acatcgtacg gccaccgttg
    18661 gacacgttga aggcgtaccc ggtatcccgc aaagcctttc gtggaggaga cactcccgtc
    18721 gtgcctcgtt ccaccccgag aatcgcacct tccataaatc cgctgtaccg atggtatgcc
    18781 ggtatctccg cccccacctc caatcgttcg gtgaggccgt atcgaagaaa cagaccggcg
    18841 cgcacggtct caaatttcat ggttacatcg gcctgctcct cccgatcccg ggcgatcgtg
    18901 gcggtattag ccgcttcgag acggatatcc aaatccccct tgcgcaacac agccgcccgc
    18961 tcaccaggca tggccaacac cagctggtcc agtgcttgaa agtttctgac cgggaaggga
    19021 ccaaacccct ccgcgccagc cagaagcggc aggccgcagg aaagcccgat gaggcagaaa
    19081 aaatagacga gatgccgcat gagtaatacc cggccgttca ctcaggcgct taataaggga
    19141 agtccaaccc ggcgaaaatc gctccgcctt cgcggctata tccgtaatcc aggcgaccga
    19201 ccacgttcgg tcgcacaatc gcccgaaaac cgacacccgg tgtcatccgg taatcctgaa
    19261 agctcacatc cttaaaggaa ttgaacacct ggcccgtatc cagaaacggg gcgagttcaa
    19321 aatccgccgt cacccctgcc aacttcgtgc gcaagatatg aatccgctct tcgatactga
    19381 aggcgatcag atgtttgtcg atgtagcgat ccatcccgaa tccgcggaga ttgttttgtc
    19441 cgcccagcga cgactgttcg aagaacggca cttgcgaacc gatcgtggcc tgcaaatcgg
    19501 cccgtacgac cagaatggca cgcttggatt cgctggggaa caactttttc acttcgattt
    19561 cgtaccgtga atacacggga tgatccccat ttttcacatt ttgattcagc tcagcatagg
    19621 ccatgacgga catgccatcg gtgggcgtga ccaggctgtc gcgggtatcg taataaaatg
    19681 aggcgcgatg cccgacaatg atggattcgc cctgaatgcc gtcgacagtc ggaaattgct
    19741 ccactgaaaa cggcaggtct gtggcgcccc gctggagttg tacctggcgc acccgctgcc
    19801 ccaccgaaac ctgcgttacc tcattcgcat agaggccgag gcgccagtac gcgcgcgctt
    19861 ctctcgccgt gtaattcgat tcatccgctt ggaccgtcga ttggcccagc ccgaagaacc
    19921 gggacgtagc atttttaaag aaggttccac cgaagttcag aaaatactgc ccgttaccga
    19981 acgccgggtc gacatagtca aacaacacct tgcgctcgat tttctctgtc agggaggcga
    20041 tcagcttcat ctgccgcccc cccggatcgt acttaaagag gttgaacacc gcccggctgc
    20101 cgacgatcga attctgaatc aacatcggcg ccatcaggta tttcaattcg ccatccggat
    20161 cggagatcag gatgggtgcg atcaaaccgg cgtcgttccc gtcgtttttg ctggtggaga
    20221 ccgaaggaac cggaaaaatc tgggtatcgg cccctgcggg agccggagag ctcaggaaca
    20281 taagtccggc cagcgccagg agaatacgga tcgacgaaaa ataatgtcgc tgcatggcgc
    20341 tcgccggaac ggtcgctttc tattgagact acggggcttt gatcttctcg gatttcttgc
    20401 ggagctgatc aacgaggtcg gaatacgagg aggtgtgaag gatcttcgta aactgcccgc
    20461 ggtaattgtt caccagactg acgccatcga ccaccacgtc atacacgtgc caatcattac
    20521 ttttgttcag cagccggtag tccatgggga tttcggtttt gccggacaag accttggtgc
    20581 gcacctccgc atactctttc tcggtgcgct cattgaggta ttgcacaccc tcgccggaat
    20641 aggtctccac ccgatcggcg taggtgttgg tcagcaacgt tcggaacaga tcgacaaact
    20701 cttgcttctc cttgtccgac agttgattcc actgcgcgcc caatgatcgt cgtgacattt
    20761 cggagtagtc aaatcgcgcc gcgacgactt tttccaaacg ctgccgccgg tcttcatgtt
    20821 tagccggcgc cttcagttct ttatcgttca agatcctcag gacctcatcc actgttcccc
    20881 ggatcgattc cgtggccgga ccggccaggg cgaacgacag cccgcccacg aacagctgca
    20941 gcgccaacag gacacccacg accatccatc gccttacatg cattccaaca cctctcctgt
    21001 gagtggtgat tccctggtcc caccagccca atgttcgcat tgccaccctc tgcaaatgag
    21061 ccggtgagat tagttcacct tgccatgtac atactggcta accaattcct ccagatcaag
    21121 ccctgactca gtgtcacgaa ttttgtcgcc gggcttcaat ggatcgccgc ccccgcctac
    21181 ggaaagtgcg agatatttat ccccgatgat gccacgggtt ttgatggaag caatcgtgtc
    21241 ggagtacaac ttgacgccat cctgaatcgc cagggccacc aatgcccggt cactattgag
    21301 gccaatggtg cgaacgcggc ccacctcgac cccggcaatc tccaccgacg ctcccggctt
    21361 cagtcctgag gccgacgtaa actccgcttc gatcggataa ttgtgtccgc cgatgacctc
    21421 cagttttccc agcttgatgg aaagatatcc caggcaggcg atcccgacga gcacgaaaat
    21481 cccgaccatc aattccagtt ttgcacgttc cataacgtct cctatcagcg actctcagcc
    21541 ggcaaccctt tgggcgcgac cgtgcccccg acaaaaataa actcgcgaat ctcttcatcg
    21601 gtcgtcttca caaactcgct tgatggtgcc atctcggcaa tccggccgtt cttcagcatc
    21661 gccacatagt cggaaatgcc aaaaatttcc ggaatctcat gactcaccat caccgcggtg
    21721 aaacgaaact gctgctgcat cgccacgatg aggtcgtgaa tggccttcgc catcaacgga
    21781 tcgaggcccg tcgtcggctc atcgaacaga atgatctccg gctccattac caacgcacga
    21841 gccagcccag cccgtttgcg catcccgccg ctcagttccg cggggaattt atgccccatg
    21901 cccttcaatc ctacctgctc cagcttctcc tcaactcgcc tggtcacgac gtcacccttc
    21961 aggcggagtt tttcccgcaa cggaaaggcg acattctcaa acaccgtcat ggaatcgaac
    22021 agggcggcgc cctggaacag catcgcgaat ttcttgcgca cctcgttgag agcccgtcct
    22081 ttgaggcggg caatgtccgt cccatcgatc cagacttcgc cgcgatccgg ctgcatgagg
    22141 ccgatgatgt gtttcaacaa cacactcttg ccttcgccgc tccgcccaat gatcgtcgtc
    22201 aatttccccg tgggaatggt gaggtcgacg ccgcgcagca cggcctgttt ccccaaggtc
    22261 ttttctaccc cgaccagttt aatcatctga atccagcaat ttatgtcatc agcgttcggg
    22321 aatccgttca catccaaacg ctgaatgcgg acggccgatg actgacagct ctatagcaac
    22381 accgaggtca gaaagtaatc ccacaccagg atcaacacgg cagacagcac caccgcttcg
    22441 gtcgtggccg ttcccaaacc ttcggcactg tgtttcgtgt gaaagccctt gtaacagcag
    22501 acccaactga tcaacaggcc gaagctgatg gatttgagaa tgccgccata gacatccttc
    22561 cattccacag ccgactcgat tgaactccaa taggcgcctt cattgccgtt cagcagttgc
    22621 acgccgacga cgtatccacc gtaaatgccg acgacgtcga acagtgcgac caataacggc
    22681 acagcaatca aactggccac cagcttggga ccaatcagat actgcagggg gttgatggcc
    22741 atcgtatcca gagcatcgat ctgctcggta atccgcatga tgccgatttc agccgtcata
    22801 gccgatcctg cgcgggccgt caccatcagc gcggcaagca ccggccccaa ctcacgaatg
    22861 atactgagcg caacggcgga tcccagcacc gcctcggagc cgaatttccg cagcgtgtag
    22921 taaccctgca gcgccaaaac catgccggta aagacggcgg tgaggaccac cacgaaggtg
    22981 gatttatagc cgatgaaatt gagttgtttg acgatttgat agaacctgaa cggcggacgg
    23041 gtcagccagg caaaggagga gagaacgaac agcatcattc gccccatctg ctccgtcaga
    23101 tcgatggtaa accgtccgat gcgagcaata ccttccacgc ctcaccctcc tcttctctca
    23161 cgggccggac gaccgccgcg cataactcct gatcagccga tgccttcacc cagagcacga
    23221 tcggcacagg cacgaaacaa cgccgtcaac tgtgcgccgg caatctgact ctgcactcgg
    23281 agacgattga gcccgatcag gctcgtcgga tgtgccaggc acgcgacgac acccttcgcc
    23341 catccagatg gcctgagaaa caggttgaag tcaagcggca gactctcatc ctcgagatcg
    23401 gagaccgtgc ggacgatcgc aaaagggatt cgatgctccg aggccaccct ccctaaggcc
    23461 gcgctctcca tgtcgagacc gatgcctccg gctcgtccgg cgatcgcgcg tttttcttcc
    23521 gccaggcaga gtacacgcgg caccgtgaca aaccctccgc ttcgcatcgg caagccttgc
    23581 acatggaccg cctgcctcac ccactcgacc atcgccggcg cgcacggcac agaaggcccc
    23641 gccttcccgc cgttttccag gatcacgtcc gtaccaatca acacgtcccc gatgccggcc
    23701 ggtcccagag cacaggcaaa tcccgtcgac cagatggccg acagcgcctg ttccgcgagt
    23761 atccgtttgg ccgtggccat cgcccgctcc ggacccactc ccatgggaat gatgcaccat
    23821 tcgacgaacg gctggcgtac caccacacaa cgaattccac cgacggcccg gacttcgctc
    23881 gcaggaaagg cgtgccgcac ggcggccaat tcccaccggg tggcaacaaa gacaccgatc
    23941 gtggtcacag cggctcccga taactgatgg cgaggggaaa tggactcgat gagcatccac
    24001 ggtcagcgag gcgaccggaa ctgtcctgat tgataggcca gctgtcgcaa ttcatccgcc
    24061 ctcgtcgttc cacgagtctt cagattgcga tacatggcca gtgcccagag agggaagtat
    24121 tggcaatacc aatgataacg gaggtagaac acgcgaggga aaccggttcc ggtatggcgc
    24181 acctcttccc atgacccgtc cttccgctga tttcgaatga ggtagtgaat acctcgggca
    24241 aggctgaatg agtctgtgac gccgcctgcc atcagggcca agagcgccca ggcagtttgc
    24301 gacggggtac tatcgccacg cccgctctcc gccacatccg cataggagag acaggactcg
    24361 ccccatccac cgtcgggatt ttgcttcgac tcgacccagc tgaccgcacg acggatatag
    24421 ggagaagaga ggtcctcacc gatggcccgc agcccggaga gcaccgacca ggtcccgtaa
    24481 atgtaattga cgccccaacg accataccaa ctaccgtcct gctcttgatc gttcttcaca
    24541 aaggtcaacg ccgaggccac ggacggatgc gtccagtcat atcccagggt ggcgagcatt
    24601 tcgagacacc gtccggccag gtcggccgta ctgggatcca acaatgcgcg atggtcggca
    24661 aaaggaatgt agttgaacac gattcgatta ttgtcgacgt cgtacgcgcc ccagccgccg
    24721 tcggatccct gcatcgccgt cacccaccgg caccctcggc gaatcgccag ccgctgctgg
    24781 tcttcatcag gcagacgcac tttagcaagc gccatcagca cgacagccga atcatccacg
    24841 tcggggaaga gctcgttctc aaactgaaag taccagccgc ccggttccgc gccgggggag
    24901 gaaataatcc agtcgcccac ggtctttgtt tgtttggata acaaccaggt ggcggctttc
    24961 tgcaacgccg gatgatcctg cgacataccg gcctcggaca gcgcattgat gagcaaggcg
    25021 gtatcccaga ttggagaatg gcagggttgc agatgcagcg catcgacaca ttgcccgttg
    25081 tccataaccg tatcgtgaat ttcgagttct tcgatctccc gcatcgcttt gacgacgagg
    25141 ggatcatcat tcttgtagcc gaggcaattc agagccatca ccgaattggc catggcggga
    25201 taaatcgcgc cgagtccacc gctccccttc atatgatcga gcatccagtt ctcggcgccc
    25261 ttgagcgcct tctggcgaac ccattcgacc ggcgagcgat catagacctt gagcagcgcg
    25321 tcgagattga tgaaaaagtt tctggccgta aaccaggtcc ggtccttctt gaatggaggg
    25381 accgtgctgt aatcaatctc cgccgggggc tgcgtgtaca gctcgtcgat gccctgttcg
    25441 ggtggcacat aacactgggg ccgtttggca aaaatgatca agagcggaat gaggaccgcg
    25501 cgcgaccaat aagaaatggc gtagatgctg aaatagaacc gcttcggcaa cagcatgatt
    25561 tccggcggca tgctgggcac gccgcgccaa tcatactgac cgaataaagc gagggcgatt
    25621 tttgtgaaca cattggccgc gacgaccccg cccttatcga ggatgcaggt tcgcgcctgg
    25681 gccatgaacg gttcatcggc tgagacgccg gaaagcttca aggcaaagta cgctttcacg
    25741 gaagcgctga tatccgccgg ccccccgtga taaataggcc agcctccaca cggaagttgg
    25801 gcggacttca aatagcggat gactttgcgc tcgcgctccg ggtcgacgca gttcatgaac
    25861 cgccgcagca tcagatattc ggagctcagg gtcgtatctg cttccagctc agctacccaa
    25921 aaaccttcgg tagtatcctg cctggccaga aaccacgcct gactcttccg gatggcttct
    25981 tccagtgctt cgagttgacc ggtggtgtgt gaaggcgctc gctttgcacc gtcgctggct
    26041 ggagcatcgg gcttactgga gacgaggcgc agcacgggag cagaggcaaa atcgcgcgcc
    26101 gctctgattc ggctcggcac cgagaccagc agactatcag atagacgact gaagagattc
    26161 ttgagaagtc gcatagcgtg ttgccgtgaa tcagacagag acggcgggat cgatagtcga
    26221 aacggttcca tcaatcaagc agtgatcaca tgaaaccgca cagtaccatg tataaccatt
    26281 agcaggactg tataacaaac tgcttcagac cagtcaaggg aagtagccct cgaagtgcgc
    26341 gccaagtgcg cgtttgagca gaagactcag cgcgctgctt ccccgacacc gtcctcatta
    26401 ggccggctgc aaatcgccga gcttgacgga gatcaaggtc gacacgccgg gctcttccat
    26461 tgtgacgccg aagagcgaat ccgccatcgc catcgtccgc ttgttgtgcg tgatgaccat
    26521 gaactgggca gtcgaggaca ggctgcgcaa gacgcttgtg aaccgcccga tgttctcttc
    26581 gtccagcggc gcatcgattt cgtccaggat gcagaacggc gtcggacgga tcaagaagct
    26641 ggcaatcaac agcgccatcg ccgtcaaagt cttttctccg ccggacaaca tggtaatact
    26701 cttcaatcgt ttccccggcg gttgcgccac gatttccaca cccggctcgc gcgcgccgtt
    26761 atcctccacc ccttcttcca acggctcttc gaccaactgc agctctgcgc ggccaccggg
    26821 aaagaattgt gcgaacacat cccggaattt ctgctgcaat tcgttgaagg tctccacgaa
    26881 catgtctttg gtggtccggt tgatcttctg aataatttcc ttgagcgagg caatagaggt
    26941 agacagatcc tgctcttgtg tcgtcaaaaa ctgataccgt tcttccaatt cacgatgttc
    27001 gtcgatcgcc gcgagattga tcgcgcccat gcggtccaac cgttcccgga ttttctgaat
    27061 ctgttctcgc aactgtggcg tctcgagcag agagaccggt gcaggtggct cttctccttc
    27121 agttacgggc tgttcctcag ttgataccac cagcagagta gccggatcga tttgataggt
    27181 gccggccagc gtgctctcga tggtcgagag atgcgccttc acttcggcct tgcgcacttc
    27241 agccgtcatg cggcgatcat gcaaggccga caaactctgc cgcacggtgg agagggtttc
    27301 ttcgacggta tgcaatccgc tcatttcttc agcctgacgt tcctgcgccg cgatgagttc
    27361 cgatttgatg ccatccacct cggcaccgag ttcacggcag agcgcctcct gcctggtctg
    27421 ctcctcgcgg ctgctctccg tagcctgtac cagtccggtc acttgctcct cgagctccgc
    27481 cgcacgtcgc tgcgcagcat ccagccgttg cgtgaaccgc gcaatatcgc tgtgagcatg
    27541 ctcgcgacgt ccacgcatgc tttcgagcga caaccgcact tcggtcagcc gttgctggat
    27601 cgccagccct tggctttcga tgacgaccag tcgttcacgg atctgaagca acccgttttc
    27661 ctggccgagc ttctctgcca cccattgctc aagttgagcc tggctggatt ccaactgctc
    27721 ctgcaaccgc gcctgttcag ccaatccccg ctgcagctct tcggccaaca tgtccatccg
    27781 ccggtgcaac tctccacgct ggcgctccac gtttgtatcg tctttctgaa gggataactc
    27841 cagcatctcg gcctcgcgga tggccctgcc cagctgctgt tcttcctcac gccccagacc
    27901 caatgcggag gctgcttcct cacgtgcgac acgagcgagt tccagcgctt gcaccgcttc
    27961 catgcggcga gcctccaact ccagcacttc ccgccggcgc tgcaggagtc ccgcaccggc
    28021 actggtccca cccccggtca tgacgccggc tgcatccaac gtctcgccgg acaaggtcac
    28081 ataggttggg cctgcaggag ccggccactg gtgctgctcc cacaattgca gcgccacagc
    28141 gagggattcg acgatcacga tgccatcaaa caaataactc aaggtggaag cggatgcgcc
    28201 ttctgcgcgg atgacatcga tggcacgccc cacgactccc ggctgcccat tgagtgcagg
    28261 ccaccaggaa gctgaagaat ccgctgctgc ctggtcggtc gcccaacgga tctgctgagg
    28321 gataaatgcg ccacgcccaa gttccttacc tttcaaaaac tccaccgctc ggctggcggc
    28381 tgagggctga tcgaccaacc agccccgtac ccgctcaccc agaatcgtct ccaccgcacg
    28441 atccagcccg gacggaatga cgagccactc tgcaagcgcc tcgcgcacac cgtcgcaggt
    28501 tttcagcgcg gtgccttctt cctctccctc acggccgtag cccatttcct cccgcaccac
    28561 accctgcaac gcgcccaggc gcgattccac tgcagccaca tcttcggaaa atcggacgat
    28621 atcgcgatcc aagcccgtga tctgcccgcc gagcccttca atacgctcga tcgcagcctg
    28681 ccgttccgcc atgagtccct ggatccgctg actggcctct tcccgctgcg ccgccagaag
    28741 ttcccgctgc tcatccaatc cagccacttg cgcgaccatc tgctcctgct cacgcgagac
    28801 ccgttccgcc cgggctgacg tttcctgctg gcgcgcggtc acctgcgcga gactttgctc
    28861 cgtgttcgct acgagcacgg cgaggttcag cacatccttc cgggcgcgct cctcttcgct
    28921 gacagcggcg gcccgatgcc ccgccagggc tttcgcttca gcatccgcct gctgaaactg
    28981 cgcctcttgc tcgacaatgt cgccttccag ttgcagcaag gtcgctcgca ggtcttcgat
    29041 ttcaacctgc gcctgctcct gatcccccgc cagtcgctcc atttcctgcg aagcctgcac
    29101 gcgttgccgc tcgaacaatt ccgtgcggtt ccgctccacc tccgcggccg tcagtgcctg
    29161 cgattgccgc tgctcggtcc cggccaaggt atcccgcacg cgcgagatgg cctcggccgt
    29221 gtcgttcatc cggagccgga tggcttcctg ctccgaatcc agacgagcct gctcggcgac
    29281 ctgctcggcc tcgagtgctt ccacctcccg cgcttcgcgg tcgacggatt ccaggtcggc
    29341 atgcatggtg cgatagtcac gggacaacaa ctcgatctcg agccccttgg cttcctgctg
    29401 tagcgtttgg tacgtccggg cctggcgagc ctggcgttcc agtgaattca gctgcttctt
    29461 cacttccgcc acaatatcgc gcacccgcag gagattttgt tgcgtggatt ccagcttacg
    29521 aagcgcttca gccttctgtt ttttgtaccg gacgatgccc gcggtttctt cgatcaattc
    29581 ccgacggtcc tgcggtgacg cctgcagaat ctgctcaatg cgtccctgtt cgatgacagt
    29641 atggcccttt gaccccgctc tggtttcaat cagcacattg cgaatatctt tgagcctgca
    29701 gggcgtcttg ttgatgagat actcgctgtc gccattgcga tagagacggc gcgtaatcat
    29761 cagttcctgg tattcgctca attgactcgg caatcctgaa atcgcatcca atcgcaactc
    29821 gcccagtccc ccgatcacca gcgagacttc caccaacccg agtggtttcc gcacttccgt
    29881 cccgttgaag atgacgtctt ccatcttctc gctccgaagc gttttggtgc tttgttcgcc
    29941 caacacccag aggatggaat ccaccacatt acttttgccg ctgccgttcg gacctacgat
    30001 cgccgtaatg cctttgggaa attgaatttt cgcttccgcg aatgacttga agccgagcat
    30061 ttccaaggac ttcagataca ccggcgacct ccagagcaag aaggttgaga agggacgcgt
    30121 tgtgaggaag aaaacgcaaa accttctatc acagcgatag aatcaatgca aaggaaaagc
    30181 ccttgatatg ggggaataaa gaggccactc ccccaatata tggaggaatg gcctgatcta
    30241 cctgtaggac aatatgagga cggccgggca gttagttcgc agaggcggcc gtgcgtgacg
    30301 cagattcaat ggtgacgagt tctttcggca ggaggaattc cacatcctct tcaatgacgg
    30361 tcaattcttc cacttcttca gaagaaccca gacgcttgag ataggccacc acttccgtca
    30421 ccaacacttc tggcgcagag gcccctgccg acaggcccac actcttggca tccttcaacc
    30481 agtccggatt gatatccgac gcggcatcga tgagatagga gggaatgccg caatgctcgc
    30541 ccaattcgcg caaccggttc gaattggagc tgttcggcga cccgatgaca aggatgacat
    30601 cgacgagctt agacaaggcc ttcaccgcat tctgacggtt ctgcgtcgcg taacaaatat
    30661 cttcctgatg cgggcctttg atattgggga atcgccgatg taaggcctcg acgatatctc
    30721 gacactcatc cacactgagt gtcgtctggg tgacatagga caggttctgc gtcttttcca
    30781 cgtggagcgt ttcgacatcc tgcacggagg atacgagatg gaacttatcc ggaatctgcc
    30841 ccaacgtccc aatcacctcg gggtgcccag catggccgat cagaatcaat tcatagcctt
    30901 gcgtgtaatc acggttgact tcgttatgca ccttgatcac caagggacag gtggcgtcga
    30961 tgacatgcag gcggcggctc tgcgcctctt cccataccga cttcgccaca ccgtgggcac
    31021 tgaagatcac cactgatcct tccggcacct catttaactc ctccacgaat acggcaccct
    31081 tgtgccggag cgagttcacc acatgccggc tatgaacaat ctcatggcgc acatagatcg
    31141 gcgcgccgta ttttttcagg gacagatcga caatatcgat cgcgcggtcg acacccgcgc
    31201 agaatccgcg aggattggct aagtatatct tcatctgctg attccctctc gcgatcatga
    31261 agggctgccc ggcttgccgg ggtatacaca tcgtctcact aagcggtcac cttacgtcag
    31321 acccgccctt gacgtcaacc gcgtcatccg catcttgcca gccccaaaag cagttgaggc
    31381 cgttgcccca ttgtgcaaca atccggccat gtcatcacct tccagcacgc acaaaaaaat
    31441 tctgatcgtt gaagatgaga aagatattct ccagctagtc aaactctacc tcgagaagga
    31501 gggattccgg acggtgtcag ccatgaccgg cacggaaggc cttcggcagg tgaaggccga
    31561 acatcccgat ctgattattc tcgatctcat gttgcccgaa ctggacgggc tggaggtgtg
    31621 caaacggatc cgtctgaacc aggagaccgc cctgctcccc atcctcatgc tgaccgccaa
    31681 ggccgaagag tccgatacag tgatcgggct tgagctgggt gctgatgatt acgtgaccaa
    31741 acctttcagt cccaaagctc tggtggcgcg ggtcaaggca ttactccggc gactggatcg
    31801 caacgccaac agtcctcaga cccaatatca ttatggcccc ttgaccgtag atctgtcgcg
    31861 gcatgaagtc cggctggagg gagaagaggt gacgctcacc gcaaaagagt tcggcctctt
    31921 ggagcatctg ctccgcaatg tcgggcgggt gctcacgcgc gacgtcctgc tcagcgcggt
    31981 gtggggatat gattattatg ggaccactcg cacggtggat gttcacgtgc gccggctcaa
    32041 acagaaactc ccgcttctgg atgacgccat catctcgatc aaatcactgg gctacaaact
    32101 gcgcgagtct gatattccgg catgaacctc agcctacggt ggaaagtcgc cctgggcaca
    32161 ctcgccgccg tccttgtcgg cctcctggtc gcgggctggc tcgtgatccg ttcggtggaa
    32221 cagaccgaac tcagccgcat ggcggaaatg ctggagacgc gcagcagctt ggccgccatg
    32281 gcgctcaggc cgttgtttga tcaaaccggg caagccgttc ccagccccct gcttcacacc
    32341 accatccgcg agctcagcca gcaggcccgt cttcgcatca ccgtcatcaa acaggacggg
    32401 accgtgctct cggacagcgc ggtccccgcc gaaggactca ctcacatcga caatcatctt
    32461 gcccgcccgg aagtggccca agcgctggca tccggccggg gcatggatat tcgagccagc
    32521 cagactaccg gagagcgcac gtactatgtc gcccggctcc tttccgaacc ggcgcgcata
    32581 caaccaggcg tcccagtgat ccgcctcggc ctgccattaa cctccatcga tgaacgggta
    32641 cggcacattc agcaggactt gctgacagcg ttcggggccg cctttctcct ggcgatggtg
    32701 ctcagcctct gggtgtcacg caatctcaca aagccgctct cggagatggc tgctgccgct
    32761 cgccaactcg ccgcggggac gcccgggatc cgcctcaccg tctcgtcatc agatgaagtc
    32821 ggtttgctgg cgcgaacact caaccagatg accgaccagc tggagacgaa gatcaaggaa
    32881 gtctccgacg accgcgcgca actcctggcc atgctgattg cgatggtcga gggcgtcatg
    32941 gtgctggact atcgaggcac ggttgttcag gtgaatccgg cgttggagcg gatgttcgca
    33001 ttagagctga cggaatcacg cggccgtcat tatgccgaat tgatccggca cgaagggctg
    33061 accgcgctgg tctcggccgt gttgcagacg cgatccggtc agggcggtga aattacgctc
    33121 tcccccagcg gcagctgttt gcgggtggaa gcgtcgatcg ccggcggcaa tcgtgagcag
    33181 gaagcctgtg ccgtctttgt cttccatgac attaccgaac tgcgtcgatt ggagaaaatc
    33241 cgcaaagatt ttgtcgccaa cgtgtcgcac gagctccgta ccccgctcac gtcgatcaag
    33301 gggtacgtcg aggccctgct ggacggcggc aaggacgacc cttcgacagc agcagcgttt
    33361 ttagaaatca tcatgcggca aagcaatcgc ttgaacctca tcctcgacga tctactgcaa
    33421 ttgtcgcaga tcgaatccgg ccaggtactg tttcgcaggg agccggtgga attgcgggcc
    33481 ttgctggaac ggacggttgc ggtgatcaag ccgttggcgg acaagaaaca tcatacgatc
    33541 gaattgtcgc ttccggacga gtatgtcgtg gtggaagggg acgaggaacg cctcgttcag
    33601 gtctttatta acctgctgga aaatgcggtc aaatacacgc cggatcaggg ccggatctct
    33661 atggcaatcc gccaggcgac gcaaagccgg acggcgtcac cgcgtccgat gattgagatt
    33721 gtcgtggcag actcgggaat cggcattccc gaagcggacc ggccgagggt cttcgaacga
    33781 ttctacaggg tcgataaggc ccgctcgcgc gaattgggtg gaacgggttt aggactcgcc
    33841 attgtcaaac acatcgtcga agcccatagc gggcatgtct gggtggaggg aaatgcgccc
    33901 aggggcagcc ggtttgtggt tcacctgccc gttgcgcagg agtcgtctac gacaatttcg
    33961 acagcagcag gtaacatata gtcgacagga gcgcagctcc ggggagggtg aagagccagg
    34021 ccgacagaat gcgacgggtc acaccccagc gcaccgccga gacccgcttg accgctccga
    34081 ctcccatcac cgtcgaagta atggtgtggg ttgtactgac cggaagtccg atatgcgccg
    34141 tggccatcaa cacgatcgca gctccggttt ccgccgcaaa gccatggacc ggttccagct
    34201 tcacgatccg catccccaac gttcgcacga ttcgccatcc gcccaccgcc gtgccaagcc
    34261 ccattgcaag agcgcaggat ccgatgaccc aggtcggcac ttccgccttg ggaagggccc
    34321 ctgctgagac gagcgccagc gtgatgatgc ccatggcttt ctgtgcatca ttcgccccat
    34381 gactgaaggc cataaaactt gcggagacga gttggagccg cgaaaacaat ctcaaggcca
    34441 aggctcgtgg cacacggaag aagagccagc tcaatacgat catcaacacc agcccgatcg
    34501 caaacccgaa aaacggcgac aggatcatcg cctccagtac cgagcgtaat cctgaaaatt
    34561 tgacggccgc catcccgcca tgggtcagcg cggcgcctac caacccgccg atgagggcat
    34621 gggaggagct ggtcgggaga cccagcatga gggtcatgaa attccacacg atggcaccgg
    34681 ccagcgcaga ggcgacaacg gtctgggtca ccgattgagg atcgacaatt cccgtgccga
    34741 ccatcttggc cacggcagtg gacatgaacg ctccggccac gttgagcgca ccggcgacaa
    34801 ggaccgccgt agaaggactg accacgcgcg tcgagaccac cgtcgcgata gcattggcgc
    34861 tgtcatgcca cccgttggaa aagtcaaaca gcagcgccag aatcactacg actaacaaca
    34921 atccgctcag ttcagccatg aatgccgcgt cctatccctc gtgtattggt caggatgagt
    34981 atcgaagaat gtgcgagggt tgctcacgtg tgcttcaagg cgatgcgctc gagaatgttc
    35041 gcgacatctt cgcaccgatc ggtgcccgcc tcgaaatttt cgtagatttc tttccacttg
    35101 atgacggcga tcggatccgt ctccttctcg aataaagacg agatggcatc gcgcgaaata
    35161 cgatcggctt cgttttccag gctattcacc cgcacgctgc actccgtgac cgcctgatgg
    35221 gacttgccga gtaagtccac cgtggctcca acctcaaccg ccgcctgata caggacattg
    35281 gccaatctga tcgccgcctc cgttggagcg acgaccttat acaagacgaa ccgatcggcg
    35341 attgcctcga ccacatccag aatgtcgtcc agcgcactgg ccaaatcatg gatgtcttcc
    35401 cgatcaatgg gagtaatgaa ggtctggttc agtttccggg cgatgtcatg agtgatgccg
    35461 tccccgacat gttcgacatc cttaatccgt ttggctttct caaccggatt ccgaaagtct
    35521 tccgtcatgt ccttcaaaag acggctgcct tcgatcatgt tatgcgccgc atttttgaac
    35581 aaatcgaaaa acgcttcttc ccggggtatg agaccgaaca taacgtcctt tctagccgcg
    35641 aggggttacc aacgcaccag tcctgtggcc caggttaagc ccccgccaaa tgctgccaat
    35701 actacgacat ctccagctgc aatcctctgc tctcgaaccg cacagtctaa cgcgatggga
    35761 agggacgcgg acgaagtatt gccatagcgt tcaatgaccg aatagagcac ctctcggggt
    35821 agcccgagac ggcgacgaag ttgctccaaa atcctggcgt tggcttggtg agcaatgacc
    35881 ctcctcacat caacggtcga gagcccaaat tccttcaaca gttcgagcat cgcctgttcc
    35941 aaatgacgga tcgcggcgcg aaacacggca ctcccccgca tccgcaggag gtgatctttt
    36001 ccacggacgg tctccgtccc gctcggcttc cgcgaccctc cagcaggaat ggtgatgagg
    36061 ccatgccctg ccccttctgc atacaggcgc acgccaagaa tgcccgcggc ctgcgggcga
    36121 atggattctt cctgcaccag caccacggca cccgccccat cgccgaacaa gacggctgtt
    36181 tctctgtccg ccggatccag cgagcgggac ttcacttcgg ccgcaacgac caagcaggat
    36241 cggatgtgac cgctccggat catcgcgtcg gccatcgaca acccgtagag aaaccccgaa
    36301 cacgaagccg ataggtcgaa cgccatgacc gactccgccc ccagggcacg ctgcacgtgg
    36361 caggcggtgg aaggaaaggc gctgtccggt gaggtggtcg aaacgagaat cgcgctcagg
    36421 gattgcggcg gtattccggc agcctcgcag gcccgccgtc ctgcctcgac cgccagatcc
    36481 gatgatgcct gccccggttc ggcccaatgt ctcgtgcgaa tacccgtcag ggccgtgatc
    36541 tgatccgaat tcagcccaag cggcttcccg acctcctcgt tatggaccac tcgagggggc
    36601 acaaaggaac cggtcccgac aatccgactg cacttcacgg aattcctact ggagccttct
    36661 gggatttggt tttacaacgc gtcgcacccc atgcagaggt gcggcgcgat tataggaccc
    36721 ggcttcagga gggtcaactc cggacattga tttcgttgct tttcatttca cgatctgcta
    36781 gaaaaattgt gtagttacgt tgtctctacc atcaatgctt gctgtgcgaa ggagtctgga
    36841 tgcatcggca ttcgagggat tggtgtgtgc gcatcgccgt catggttgga ctgctgtgtt
    36901 tttcggccgg gtgttccagc aaacccaaaa ccacggccca aggcaaaccc gtgagcggaa
    36961 ccgatgagca aatctttctt ggcgacacca tcgagaaaaa ttacgatccc aacgtcatca
    37021 tgaagcgcgg cgaggccttt ttcgacaagg aagagttcgc cgaagccatc gttgaatacc
    37081 agcatttcct ggaattgcat cgtagccacc agcttgccgt ctatgcccaa tttcgcttag
    37141 cggaaagcca tcttcggatg ggaaaatcga ttgaccgcga tcccgatccc attcagaaag
    37201 ccattaccgc atttgaaaaa ttgcggaagg actaccccaa cagcaaatac gaggcccagg
    37261 cgctccagcg tctcgctgac tgccatgatt ggctcgcgaa gacgcatctg tttgttgggc
    37321 aattttacta tcgtcgctcg tcgtatctag ctgcggccca tcggttcgac atgatcatga
    37381 aggattatcc ggacaagacg gtagccccgg aagccttata ctatctggcg ttgacgtacc
    37441 aggagctcgg cgcgaacgat tgggcgatgg aaaaactcca gctcttagcc gaaaaatatc
    37501 cgaatagtga tgtggcggga agcggccgtc gattactggc caaactagag aagaagtcgc
    37561 cgccggcggc catcgtggcc agcaaagaaa cgccggctcc acagagccca ccatctaaca
    37621 cgctcctcgc ggcctccgtc ccatcgacct ttgctgcgcc cgccgtcccc gagctcaaac
    37681 gggcgccgag tgctgccttg tcccagccct tcgtctcatg ccggctcgga gcctggtgct
    37741 gacctagcgc ttacctggct cactacccta tcgcagatgc aatgcttcga ggaggaggtc
    37801 gttgactgac gccttcaggc ggttcttcgc gttggggagg aattgctgag ccgtcgtacg
    37861 cccctgcagc acttcgaaat aatcctgaac gacatcctga taacgcccca aaagcttgaa
    37921 ggccaggcgt gggaacgcat agataacctg agccattctg gccgtcacgc gaaagtccgg
    37981 aaggatttcc cgccgcagag cagccgcgta ggcagacacc gccatgtggt ggtcatctcg
    38041 atgggccagt atcgcatgag ccgccagttg tcctgaacgg atcgcgtagt agatcccctc
    38101 gccaaacaac gggtcgacca gatgggccgc gtcaccgacg agtgccgcgc ggcctgcgac
    38161 aaaacgggac tcttcgtcct gctcccgctt ttcagattct gtatacacag gaatcggatg
    38221 ccctgccgga cgaggcaccg cccccccgat cacgtgttgc tcatccgtga caaagcggtc
    38281 aaaggtggcg cgcaggctct tcgatttccg gcgaaactct ccgactccta cagaaaggca
    38341 tgctctcttc gggaatatcc atccataccc ctgacgtgcc gcgcccacat ctacgagaat
    38401 cgttgacgca gaatgaccgt gtctgccatt gccaagggga acttcgcttt ccaatgcggg
    38461 agcccggtac tgagatcgtt gtgggaaaaa ccgcctggcc acgacactat tcgcgccatc
    38521 tgcgccgacg acgatctgcg cccgatagcg tccctgtgct gtgacaactt ccacgccatg
    38581 ttgatcctgc atgagttcca ccacgccgtg gccggtccgg atatgcgcgc cggcctgaat
    38641 cgcttcctgc acgagatagt gatcgaaccg gtcccgcatg accatgtagg caatcggccg
    38701 cgctgattcg atcagcagag ggtcctggcc ccgatagaca aactgcacac cggtcacaga
    38761 ctgctcgacc acggagtgaa aaccgggttc cagcgcgtga tcaatacgcg ccgacagacc
    38821 gccgccacac actttgtacc gggggtgggc atccttatct aaaccaagta ccgtcaaacc
    38881 gcctcgacta agagccgcag cagccgtcgc tccggccggc cccatcccga caatgattac
    38941 atcgtacgtt gtgggtccgt atccatcagc catggttaca caccggttgt gaaagggctt
    39001 gccgcgcaag tcttcggcga ccatcgtgag aaattgttgc tgcgtgggag aggtcaggaa
    39061 gagccggaga nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    39121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ggcgaccatc
    39181 gtgagaaatt gttgctgcgt gggagaggtc aggaagagcc ggagagggaa gcactcatga
    39241 ggcctgatta ttgaccaaga taccagccaa tcccgtatcg ctcgagaaag ctcgtaatca
    39301 tggtcaacga atttccatag atcatcacgc ccacgacaat gagcaacacc ccgctcaccg
    39361 tggagactcc ccaaagatag gagcgcactt ccttgaagta gctcaggaac cgatcgaccc
    39421 ctagcgccgt gaggaacaac ggcaaggcta atcccaggga atagaacgtg agtaacacga
    39481 ctccactgaa catcgattcg gtcgtgctcg catacagaag gattgttccg agcacaggcc
    39541 cgacgcacgg cgtccaaccc gccgcaaatg caatgccgat caagaatgat ccgagaaagc
    39601 ctgccggacg attccggaat tgataccggt gttccatttt caggaagttc aaattcagaa
    39661 tgcccaggag ataaagcccg aacacaatga cgacaatgcc cccgaaacgc cgcaaatgct
    39721 cctgataggt aatcaacacc tggcccaaca gactcgccga agctccgaac gccacaaata
    39781 ccgttgagaa ccctgcgata aacagcaagg agttcaaaat gatggccttg cgaaaacggc
    39841 ttcgctctga aacgtcggtt agttgctcga tcgaaaggcc cgtgatgtag gaaatgtagg
    39901 acgggaccag cggcaggacg cagggagaga caaatgagag aaggccggct gagaaagcgg
    39961 ccaccaagga aatcgattgc actgagtcgg tcatactagg acccttgcaa aagcgcttcg
    40021 accaaccgtt tccccgctgg cgcgctccag tctcgagcgc cgggaattcg attccgaatg
    40081 atacctttgc gatcgatcaa aaatgtcatc ggcagctgtc gggcgccata ctgaagtccg
    40141 attctgaaat cggcgtcgtg aaggacggga aatgtaaagc cgacttcctg ctgaaagggg
    40201 cgggtgacgg ccgtgccttg ggcatcggtt gaaaccgcca gaatctcgaa ctccttccgg
    40261 ctaaacgatc gataaagccg ttccatcgcc ggcatttcga ttttgcaggg accacaccac
    40321 gtggcccaaa aattcagaag cacgaccttg ccgcgaaact ggtccaaagt gacattgaac
    40381 ccctcggaat ccttcagtag aaagttcgga gcctcttcat caacctgcgg cgcagggctc
    40441 gccaccagaa ttggagctgg ggctgggctc aataggggcg aggcccatgg agcgtcggca
    40501 atcatcactc cgcctatcat caatccgccg acaattatgg agagcatcat ccaacggttc
    40561 atcatccgcc tatagcgctg ggactgcttc aacagtggct gcacttgccg ccttttcagc
    40621 aggcttgagc aattgcgtca ggactttgag attatctaat cgcgtccaat cccgaggacc
    40681 aatcactttt tcgcgcaaca caccttgctg atcgatgata taggtttcag gaactcccat
    40741 caatttgtag cgtttatccg tttgtcccca ggagtcgacc aggacgggaa aggtcagatt
    40801 caggcctttg acaaagggcg ggatctcttt cttagtcgtg acccggtcga tgctgactgc
    40861 cagaatcacg agtccgtcct tttcaaaatt cttgtacagc acttccatgg aaggcatttc
    40921 ttcccggcag ggtttgcacc aggtggccca aaaattcaaa aagacgactt tcccccgata
    40981 atcagacaag cgtaagggct tgtcgttcaa gtcaggtagc tgaaagtcgg gggcctcttt
    41041 tccgacgatc aacggctcat actttgagct ctgcagccag acgacgagaa acatcacgcc
    41101 aagaatggct gcggcagcca gcaccacgac cgttctggaa ggaccacttc gtgtcgtaac
    41161 gccgcttgaa ctttgattca gaatatcact catggtctac gcgtacgcat gaagaccaga
    41221 gagcagaaaa ttcactcccc agaaacagaa gatcaccatc agaaacccga agatcgcgta
    41281 gatggccgcc ttatgccctt cccacccacg cgtcatgcgg gcatggatat aagcgccgta
    41341 aatgagccat acgatcaacg accaggtctc ttttggatcc caactccagt aaccgcccca
    41401 ggcgtagttg gcccacatgg ccccgagaat gatgccgaaa gccagtagcg ggaagcccaa
    41461 cataatggcc ttatacccga gttcatcgat tgtttcgagg tctggaaagg ccgcatagaa
    41521 acgggactga ctgccccgat tcaccgcccg ttccttgaac agatacatca accccaaccc
    41581 gccggccatg gcgaatgccg catagctggt tagggttacg gatacatgga tgtagatcca
    41641 ataactattt aacgccggca ccagcggttc tgccgtctgg tagcgatagg gcagcagcga
    41701 cgctgcgccc atcgcgataa acccgatccc caccacaaac gctccgacag ccttgatccg
    41761 gtaccgaaac tccagcagca cgtagccgag aatgatcgcc cacgaaacgt aggccatggc
    41821 ttcaaattga ttggaccagg gggcaaaggt cccggaatgc tccatgcgct cgaacgcccg
    41881 ggtcatcagg gccatggtat tgagcaccca cccaaacacg gtgaccaggg tggccacctg
    41941 tcctaattga gtcgcccaag ccccgtcacg gtcttccagg ttctcaatgg gatgccccgc
    42001 cggagccatc tgcatagccg gacgctttgc gaacagatag gcaacataga ggcccagcgc
    42061 tgcgagatag agccagaacg tcatatcgaa caaaaacaat gatcgcatca tacgggcctc
    42121 cgtctatcgt agagtgcagc gtcgtcctga atggaatatc cgtcaacggc gctgaaacgg
    42181 gctttaagaa gaagtcttgg cttgaatctt ctccgtcaat ttcttgaact ctttttggaa
    42241 gtcgatctgg cttttgtgcg tggttccgcc caaatgaacc gtcacgcccg attcgccggg
    42301 aagaatcctc gcccacagcc gccggtgata gatgagggat gacaatgtca tccctaccac
    42361 caacatcgta cacccgatcc ataccatcat gatgcccgga ttcctggcaa tctgcagacc
    42421 ggtgaatttc ttcggttgat acccgataaa ttcaaactga taggcggaat ccttgatctc
    42481 aaacaggtcg gggtaatgat aaaacaccca gggggtcgat tgcacggtgc tgcgctcatc
    42541 aaccgccaga cgaatagcag gattgctatg ttcggcggtc ttggaaaaga ccttcttttc
    42601 agtcgaattg aacgcgaagt cggccacgaa gtccgtcatc ttcattttca acggaagacc
    42661 ctcgaccgct ttttccttat tccactccaa atccaccgtc gccacaacct tgtccgacgc
    42721 cttatcctta atattgatcc gcgcggcctc gatttggtcc caggcatccc cgtaactgga
    42781 ctggtaaaac cagattccct tatagaccaa ggggtcgttg accgtgatcg tcttcgtcat
    42841 ggtcggagcg ccttgatcga tgacggtcaa ggtgctgttg taggacttga cggagccatt
    42901 ctcgtgatag tcgatccaga acttatcgac ccgcaggtca aagtttcctc tgggtatatg
    42961 gtacgtctgc ccctctagac acacgccgaa ctcggaaaag ccgtaatagc tgccgagcag
    43021 ccccccaagg acaatcactg tcgcacttag atgggcgaca tgcgcgccga cccggcccat
    43081 gattcctttg gtcgcataga cggtgacctc gccgggatca ctcttagcca gcaccttgta
    43141 gcctttttcc gcaaaaagcc tgaccaggga ttccgcaact gtttctttcg gttgattgag
    43201 cgagagggtg gtctgctgct tcatcccttg aatgaatgcc aaggaaacac tgactttatc
    43261 ctgacgcatg gagcgccaga cgctgggaaa tcgtttatgg aaacaggtca gcgagttgac
    43321 gcagagaagg cctaagagac cggtaaacca ccaggtgtga tagacgtccg taaagcccag
    43381 acgaagaaac catcgatagg cctcttcccc atactcctgc acgtatgttt ccggacgctc
    43441 accttgctgg atcactgtgc cgatggtcgc cgtcatggcc agcacgatga acaggaacat
    43501 cgccagctta atggaagcga aaaagtctac gacttcgcgc gaaaactctt cccacccgag
    43561 gccggacgtg gaagggccgg aggcgctcat ctctgatgct gcgtcgggtt tatcgttcat
    43621 gaatccacac acctcgctgc ttcgacctgg ccgtcataca gatcccatca tcataacgaa
    43681 tgacgagctg cgtgtgggac cctgcatcca tgcaggccga taccacgagg ttgggagtgc
    43741 cggggcagag cgtttgatga aaaatgttcc aaatacgcga aaagtaagct atcttacaag
    43801 tcgtctcgaa gagctgtcaa gcaagacccg agtctcgcga aagacgctat caattccgtc
    43861 agaacggtag acaaaaacca cccggtcagc tactattgcc gtagcgtttt tgcggggttg
    43921 ccttatctgt gcacgtgcag catcttccac gctcggtcgt tgtgccgcct aactctaacc
    43981 accgcatcct cgaatcactt cacttccagg gggaacaatg agacataact acctgtttac
    44041 gtctgagtcg gtcactgaag gacacccgga caaaatcgcc gatcagattt cagatggaat
    44101 tctagacgcc atcatcgccc aagacaagac atcgagagtc gcgtgtgaaa ccatcctgac
    44161 aaccggtatc gccttcgtcg ccggcgaaat ctctacgaaa gcctatgtgg agattcccga
    44221 tatcatccga gacgtgatca aggatgtcgg atatacagac gcctcctggg gattcgactc
    44281 taatacgtgc tcagtcctga cctctatcca tcaacaatcc agcgatattg cgatgggagt
    44341 cgattccggc ggggcgggcg atcagggact gatgtttggt tatgcgacca acgaaacgac
    44401 cgaactcatg cccatgccga tcgttttggc ccatcgcttg acgaaacgtc tggctgaagt
    44461 acggaagaaa aaagtcttga agtgggtccg ccccgacggc aaatcccaag tcacagtcga
    44521 atacaaggat ggcaagccct tccgtattga taccatcgtc gtctccacgc aacacagccc
    44581 ggatgtgacc aataaacaga tcgagcgaga tctgatggaa tacgtcatta agccctccat
    44641 gccgaaaggc ctgtacgacg caaccagcgt gaaacatcat atcaatccta ccggtcgatt
    44701 cgtcgtcggc ggtcctatgg gtgacaccgg tttgaccgga cgcaagatca ttgtggacac
    44761 ctacggcgga catggcagcc acggcggagg tgcgttctcg ggcaaagacc catccaaggt
    44821 cgaccgctca gcctcatata tggctcgcta tattgccaag aacattgttg ccgccgggct
    44881 ggcctcgaaa tgcgaagtcc agctggccta tgctatcggc gtcgcagatc cagtctcggt
    44941 attggtcgac accaaagaca cggagaaggt ggctcccgaa agcctcgata agttggtgcg
    45001 gaaacatttc ccgctgaccc cgcgcgggat tatcgaccac ttgaaactgc gtcggcccat
    45061 tttcaggaag acggccgcct atggacactt tggtcgcaac gaaccggagt ttacgtggga
    45121 aaagaccgac aaagcgaaag ctttgcgtaa ggatgcgggc ctctaaggtc ccgtcacgcg
    45181 tgataccagc cgaggggggc gggttgtaag cccgccccct tttttctgca atcgaagatc
    45241 aatcatcact cacgacacag gaggaggaac cagtggatta cgacgtgaaa gatatgggcc
    45301 tggcggatca aggcaaactg aagatcgaat gggccgaagc cacaatgccg gtgttgcgat
    45361 tgattcgaaa acgctttgaa aaggagcagc cgtttagagg cattcgcgca accgcctgtc
    45421 tccatgtcac gactgagacc gccaatctta tgaagacgct caaggccgga ggggccgacg
    45481 ttcgcctctg cgcctctaac ccactcagca cgcaggatga cgtcgcagcc gccctggtga
    45541 aacacgaagg catcccgact tttgccgtca agggggagga caacaagacc tattatcggc
    45601 acattgaatc ggccatcgct cacaagcccc acctttcgat ggacgacggc gccgatgtcg
    45661 tttcccattt acactcaaaa cgaaaagaac tgcttcgcca tgtcattggt ggaaccgaag
    45721 aaaccacgac cggcgtcatt cggcttcgca gcatggccga gaagaaagta ttgaagttcc
    45781 ccgtcatttc cgtgaacgac gcggacacga aacacatgtt cgataaccgg tacggcacgg
    45841 gccagagcac catggacggc atcgttcgcg ccaccaatcg gttggtctgt ggttcgacgc
    45901 tggttgtggc cggctacggt tggtgcggac gcggcatcgc cacgcgcgcg cggggcatgg
    45961 gtgccaatgt gatcgtgacg gaaatcgacc cactcaaggg gctcgaagcg gtcatggacg
    46021 gatttcgcgt tatgcccatg gacgaagctg cgccgctcgg agacttcttt gtgaccgtca
    46081 ccggtaatct caaggtcatt cgcggtgaac atttcgcagc aatgaaagac ggagcgatcg
    46141 tatgcaactc cggacatttc aacgttgaat tggacatccc cgcgcttgag aaactcagca
    46201 agaagaaact tgccgtgcgc tccggagtgg atcaatacac cttgaaaaat ggccgtcgcg
    46261 tcagcctcct tggagaagga cgcctcgtga atttggcgac cgctgaaggt cacccctcca
    46321 gcgtcatgga catgagcttc gccaaccagg cgctgggcgc ggagtttatc gtgaaaaact
    46381 acaagaaact ggagaagaag gtgtacccgg tgccggcgga tatcgacaaa gagatctccc
    46441 gcctcaaact cgccggcatg ggtgtgtcga tcgacaaact caccaaagag caggtgaagt
    46501 atctggcttc gtgggaaatg ggaacctaat ccaaaacccg tattcccgtg ctcgcaagcg
    46561 gtcggttgcg gctcccgcac cggccgcttg ccttttctga atggcatgcg agccgcaaac
    46621 agcgtctcct cactaaacca ctcaagacct gagaatgcac tcgcattgat gatggctttt
    46681 tcgtgcttcg atgccaatcg ataggtgcat ggccgatagc ctcgcgattg cattcacgct
    46741 ggggatgctc caaactgaat tgcaggcttt tctcaagcgt gttgccggac acatcagtct
    46801 aggcaggtag cagtttacct cggtgaagaa cgtgtctcgc cgaagcaagg tcaggtctct
    46861 atggcgactg tccgcatcgg cttgtcaggg tattcttata agccatggca ggggccgact
    46921 cgattttacc ctccaacgct caagcaagca caatttctgg agtattattc aacgcgatac
    46981 cgcacagtcg aactggatgg agtatggttt cggctgccta ccctgtcggc agtgacaaaa
    47041 tggattgagc agactccggc tcattttgtc ttttcagtaa aggcacatcg taccatcacc
    47101 cacgtgaagc gactgaggcc cgatgcggcg tcctttcttc acaccatgtt ggagcatctc
    47161 gctcccttag ccgagaaaca gaagctaggc cccatccttc ttcaactgcc tcccaatttc
    47221 aaacgaaacg atgaccgcct agctgaattc ttgcaaggcc tgccccccac gtatcgctgg
    47281 gtcatggaat tccggcatga cagctggaat catgccactg tggaaaacct cttgcgccgg
    47341 tttcgcgtcg cgtgggcggc tgttgaaacg gatgatcgac ccgcggaata ccgagacacg
    47401 gctgacttcc tttacgcccg tctgcgccgc agccaatatt cgaacaaaga cttaacgcgg
    47461 tggggtgaat actttctaca gacgagacgg aatgggaagg attgctacgc ctactgcaaa
    47521 catgaggacg aaggctcacc ctggatgtgg gcagatcaac tgctgaagat catgaatgtc
    47581 gggacactac cgggctgaaa tcatgggcaa ctcccgagag ctctcggctt cctgctgaat
    47641 gcgctggcgc tccgctttcg attcttccag cacgctatgc aataattcat cactcaactg
    47701 cgtcagctgc gcagccgcat ctttcatctc cgcatgttcc acggcgcgtg agagcacctc
    47761 tgccttagtt gcccccttct tctgccccag aaatggcttg atgatgagat aggcaacatc
    47821 gcggaatggc atatagcgca agaatcggcg gagcaacttg aacgtctgaa ttggatagcg
    47881 ggtgagcttg tagatgaaca gtttcttaag cccctcctgc cggaccgaat tgatggtcgc
    47941 gcctggcaag catgtaggat cgatttccga acacttaaaa tatttgtacc aatccttagc
    48001 atcactcacc aatccacgct tgatgtactc ctgccacaag ggcgtccccc gatagacaca
    48061 cagtcgattg aatccaaacg tatccaatgg aagcttcgac gcgaagtcga atgttttttc
    48121 catgtcctcc acagtctcat caggatttcc tacggtgaaa aagccgtgga caatttcaat
    48181 gccggctttt ttagcatttc tcactgcagt ctctacctcg gccaacgtct gttccttctg
    48241 caaacgatcg agaattttct ggctcccgct ttcgatgcca aacatcaccg ttcggcaatg
    48301 ggctttcgcc atggcgggaa acagatgctg tgcgaccgaa tccacgcggc cttcaattcc
    48361 ccattgaata gaaagcttgg catcaatgat gccattgcaa attgcatcaa tacgcttcgg
    48421 ctgcagtaag aagtgatcgt ccacgaaata aaccgagccg tacccgtttg cttctaaaaa
    48481 cttcagctct tcgacgacat gctgggcgct gcgcgctcgc catttccctt cgttgaagat
    48541 cggaatatca cagaatacgc agggccatgg gcaacctcgg gacgtctgca tggtcgtaaa
    48601 gcgctccatg gacaggactg ctgggacgtc caacggcatg gattcgacga agtctagctc
    48661 taaactttcc cgatccggga aaggccattg gtccagatgt cgctccatgg cccgattcgg
    48721 gttattgatg acttttccgt ctttcgccca tgtcacgcca gccacatcct tggggtcgtc
    48781 gatatggtcg agcaaatcca ggagcaactg ttccccgtca ccgcggcaca caaagtcgac
    48841 ctccggacat tgcaacttga ccaggcccgc gttcaggctg gcaaatacgc caccgaaggc
    48901 cagcttcacc gagccatccg ccacgcgaat ctggcgggcg agaatcttcg cgtaaggata
    48961 actcgtcgta ctgagaaagc tcatcccgac gagcgccggc tttcgtcgct ttatttcttc
    49021 aatgataaat tcgttcggtg tctcagggtg cgcctgatcg aacatgacac attcgtgacc
    49081 tgcccgttta aggacggccg agagagacat aatgccgatc ggcgggaacc ccatgacccg
    49141 aatacggcca ttcttcgctc gcgtcttggc cggaagcgcg tagaactgag gatcacgcac
    49201 atgtatgaga aacacgagca tagtggcgtc ctttcatgga cagttcggac ccttaccgga
    49261 cggttgcggc tccggaaaga aaccagatcc gatcaggcgg gccaacgttc gagggttaat
    49321 cgcctcacgc tgggcgccat acagtaccac gtctggcatg gagggaaaag ggaagattct
    49381 gacatgggcg tcaaaattcg aaggcgtcca gtgattcacc catacagctg cacacgtcgc
    49441 taaaaacaaa gagggcgtcg gaccggtccg acgcccttca gtggatacat actggagatg
    49501 agttaccggc caagtgcctt catcaccgca tgcccaattt cggcaggatt cttgacgact
    49561 cgaactccag cggattcaag agccttcatt ttctctgttg ccgtaccttt accaccagaa
    49621 ataatcgcac cagcatgtcc catacggcga ccaggaggcg ccgtgatacc ggcgataaag
    49681 ctgataaccg gctttttcac gtgctgttta atgtattctg ccgccttttc ttccgcgtcg
    49741 ccaccaattt ccccgatcat aaccacagcc tgcgtttcgg ggtccttctc aaagagtggc
    49801 aacacatcca cgaagccggt gccattaact ggatctccac cgatacccac acacgtcgtc
    49861 tcaccaagtc ctaacgtaga gagttggtgc accgcctcat acgttaaggt cccactgcgc
    49921 gagacgactc caaccacccc gcgcttatgg atgaatccag gcatgatacc gattttcgct
    49981 tcgtcgaccg taatgactcc aggacagttt ggcccgataa ggcgcacatc acgtccatgt
    50041 agtgcccgct tcaccttcac catatcattg acgggaattc cttcggtaat gcagatgatc
    50101 aatttcacgc ctgcatcggc agcttccagg atagcgtctg cacagaaggg cgggggcaca
    50161 aaaatgagag aggtatcgca gtcggtcttt ttcaccgcat cggctaccgt attaaagaca
    50221 gggatccctt caacttcctg gcctgccttg ccgggggtga ctccagcgac catcttcgtc
    50281 ccgtaagcct tgcactgcga tgcgtggaaa gatccttcct tccccgtgat tccctgtacc
    50341 accactcgtg tattcttgtt gacgagaatg ctcacggtct tctcctttac gccgccttgc
    50401 cggtcagttt gacgattttc tgcgctgctt cccacagatc gttggcaacc tctaacttga
    50461 gtccagactc tgccaacagt ttccgtccct catctgcatt ggtaccttgg aggcgaacca
    50521 ctaagggcac cgtaatcttc acttctttcg ccgcttcgat cacgccatgc gcgatacgtt
    50581 cgcaccggac aatgccgccg aatatattga taaagatacc tttgacgttc gggtccttca
    50641 gcagaattcg gaagcctgcc gctaccgtgt ctttcgtggc cccgccgccc acatctagaa
    50701 aattggcagg ttcactgccg gccagcttga tcacatccat cgtcgccatc gcaagacctg
    50761 cgccattcac catgcagccg atattgccat caagctttac ataattgaga ttattcgccg
    50821 tggcctcgat ctccaacggg tcctcttcat tgagatcccg cattttctgc acatcttcat
    50881 gtttaaaaat tccgttgtcg tcaaacgaca ccttcccgtc caacgccacc agtgtctttt
    50941 ccttggtgat gattaagggg ttgatttcga cgagcgcggc atgtttctcc atgaacaggc
    51001 gataaagatt accgagcatc tgcacgaacg ggttgatgac ggccggctcc atgctctgaa
    51061 gccccaaggc gaaggccaca ttgcgaccat tgtgcccttg aaatccgaca gccggatcaa
    51121 tcgcttcctt aataatcttt tctggggttt tctcggcgac ctcttcgatc tccatgccac
    51181 cttcagtact ggcaataaag gtgggccagc cggtatcgcg atcgaccaaa atactgagat
    51241 agagctcctt ggcgatattc gcaccttctt caagaagcaa ccgatggact gtcctgcctt
    51301 tcggtcccgt ttgatgcgtg atcagagtct tcccgatcaa ttctttggcg agccctgcga
    51361 tggcacccct atctttcgtg atcttgacac caccggcttt ccctcgtccg cccgcatgaa
    51421 tttgagcctt tacgacaaac acaggggtat ttagttcatt ggcccacgca gtcgctcctt
    51481 ccggcgaggt aatttctttt ccacgcggca ctggcacccc aaactgtgca aataactgct
    51541 tggcctgaaa ctcatgaacg ttcattgaat cctcatacga gctagtggct tatgaaaaac
    51601 gacatagtgt gcgcagaaac ccagtgatgt tcggctgtaa aaacgtacga tcatttggta
    51661 gcggtacgct ctggttcttt gcgggtatag gcgggaagaa tcatgggaga aataactcca
    51721 ctggaatttc catgcttctt cgcctcagct cgaaaccgct tcaaatggtt cagcgtcagt
    51781 tttccttgag acatggatcc ggcacgtgat gcggcggtta aacccgaacg tttaccgaag
    51841 accatcagat caagcaagga attgcccatc aatcgatttc gcccatgcag tcctccggat
    51901 gcttctcccg cgacaaacaa gttcttcacg ttggtttccg agttcgcatc gatcttcact
    51961 ccgccgttct gatagtgcaa ggtggggtag ataagcacgg gatctttact gatgtcgatt
    52021 ccgaaccgtt cgaactgcat catcatcgca gggaaatgct tctctaccgt cccggggcca
    52081 tgctccgcat caagcaacgg cgtatccagc cacactccga tccgacctga catcgtgcga
    52141 ataccacgac cttcctcaca ctcccgaatg atcgaggagg agacgacatc gcgagtgtcc
    52201 aactcattga caaaccgctc tcccttggcg ttgacaagat ggccaccctc tgaccgaata
    52261 ccttccgtga ccagagcccc gatcaactgc tcagggtaca ccgcgcctga tgggtgatac
    52321 tgaaaggtat cgatatggtc aagcttggct cccatccgat acgagaggca taacccgtca
    52381 ccggtagcac cgtagtgatt gctggttggg aatccctgga tatgtaagcg accgattcca
    52441 ccggtggcca gaataaccga cttggcggcg acaatgacat gacggtggtt gtcgagatcc
    52501 ttaaatatgg ctccggtgca ctgaccgtta tcatcgctca ataattcgac agctgcacag
    52561 aactcaagta gctgaatctt ttggttcagc acctcgtcct tcaggacccg catgatttcg
    52621 aggccggtgt agtccgagca ggtgagaaga cgcggcttcg agcttcctcc accttttttg
    52681 acatgcaaat tgccgtcggc ttgccggtca aagagtaccc cgagttcaat cagccatttg
    52741 gcaatggatg gcccctcttc aaccatgacc ttgagcagct catggtcgtt ctgcatgtgt
    52801 ccgcccttga gggtatcaag aaaatgtgtg accggagagt cttcgggggc aacggagatt
    52861 tgcatgcctc cttgagccat cacgctgttg gaatcgccaa gacgaagttt tgttgccagg
    52921 atcaccttcg caccggatgt gtgagcgtga agtgccgccg cacaccctgc tcccccgccg
    52981 ccaataacta ggacgtcggc cgtatattga ggtgtcaagt cgagatgctc ggggatagag
    53041 ctatcgcctt caagcagcgc cgccagctcg acaacggttt tgtcgtcggc attgggccca
    53101 aatcgaatcg gccgataggc actcgcccga taatcggggt gatacttatg aattaactgg
    53161 tcgcggtcgg caggggaaaa ctttggaatg gtctgcttgc gacgagcatc tcgggtttgg
    53221 tgaacaatct gctggagtgc atgaatatcc atggtttcac tttcagcgcg gagcacagta
    53281 cccgagccat gcgctcagaa ccggctaacg gcacaatgca ttactttacg gtcgcacagt
    53341 gatcggccaa ctcctgttcg ttcatcgcga gcactttgtt ccactcgtcg ttgaatcgac
    53401 cgtcttgaat ttctttaatg cggagatcaa ggccctgggg cttctcggta aaatgcgctc
    53461 cttgggcccg gctgacatat aaggccacca ggtttggcgc gatgtcggca atacagacgg
    53521 gcgtgcacat gccgcacatg acacaatcca taaacatttc tgacacgctt ttgaagtcgc
    53581 caaatactgc tttccagacg ccttcacgca catcaatttt ctgggggcag gcttccgtgc
    53641 aagcgttaca gtttctgcag agcggcgcct cggggtacaa attgaagagg tcttgcttgg
    53701 gatctttaag cgactgaatg tcgtaaagcg ctttgcgggc tggaaacggg ggcatgatgg
    53761 taaaggacat gccgtcttca accgccatct gacaagccaa acaggttcga accttcggat
    53821 cgtccttcgt gcggtaatat gttgcacagg cgccacagaa accaccgaga caccctgcgc
    53881 ctctcacgac ctcctggcca gtatgccaca aggccttgat caccgtaata ccttccggca
    53941 cttcgtactt tttaccggaa atctcaatgg tcaccatttt gtggcgcaat acttccggct
    54001 gatcgatcac attggtgtct tcttgtgcca tggctttctc gtcaatcgta aaaaggtgcg
    54061 gcgcaagaag gacgttggtc cttcttgcgc ctgaccggat caaatcatga tcgcttaagc
    54121 aatcgcgtca atgattgcgt tcagcgttgc gcttggccgc agggctttag cggctttcgc
    54181 atcgttcggg tggtaatacc cgccgacgtc ctggggctta ccctgcgcgg caagcagttc
    54241 gccgtcgatc ttcttctcgt tgtcgctcaa atcctttgca attttcgcaa atcgctcagc
    54301 gatcttcttg tccgcggttt gggccgccaa cgcctgcgcc cagtagagcg cgaggtagaa
    54361 gtgactgccg cggttgtcga tctcgccgac cttacgcgcg ggtgacttat tgctctcaag
    54421 gaacttcgcg ttggcttgat ccagcgtatc cgccaaaatc ttcgccaccg gattgttgcc
    54481 caccttcgcc agatgctcaa gcgatgcggc cagtgcgagg aattcaccga gagaatccca
    54541 acgcaaatag ccttcttcct ggaattgctg cacatgcttc ggagccgatc cccccgcgcc
    54601 ggtttcgaac aagccgccgc cgttgagcaa cgggacgatc gagagcatct tggcgctagt
    54661 gccgatttcg agaatcggga acagatcggt gagataatcg cggagcacgt taccggtgac
    54721 ggaaatcgtg tccttgcctt ccttcatccg ctcgatggag aagcggcagg cttcggctgg
    54781 cgacataatc ttaatctcca gaccgttcgt gtcgtgcttc ggaagatagg cgttcacttt
    54841 cttgatcaat tccgcgtcat gcgcgcgggt cttgtccagc cagaacacgg caggggcgcc
    54901 tgttgcgcga gcgcgcgtaa cggccaactt gacccaatcc tgaatcgggg catctttaac
    54961 ctggcaggca cgccaaatat cgccggcttc cacctgatgc tggtgcaaga ccgtgccgtt
    55021 cgcatccacg atgcggatgg tgccgttggc tggcgccttg aaggtcttgt cgtgtgaacc
    55081 gtactcttct gccgcctggg ccatcaaccc gacattcggg atcgtgccca tcgtgcgggg
    55141 gtcgaattgg cctttttgct tacagaactc gacgacctcg tggtagatcg gcgcgtaact
    55201 ggcgtctggg atcacgcact tcacatcggc cagcttgccg tctggccccc acatcttccc
    55261 gctgtcgcgg atgacgggag gcatggatgc gtcgatgatg atgtcgctcg gcacatgaag
    55321 attggtgatc cccttgtcgc tgttcaccat cgccatcggc gggcgcttct gatagaccgc
    55381 ctggatgtcg gcttcgatcg ccttgcgctg gtcgtccggc agggacttga tcttcgcata
    55441 tacgtcaccg agaccgttgt ccggatcgac gccgagcttc ttgaacgtct cggcatgctt
    55501 ctcaaataca tccttgtagt acacggtcac gccatgaccg aagatcttcg gatcggagac
    55561 cttcatcatg gtcgccttca tatgaagcga ccaaaggaca ccctgcttct tggcatcttc
    55621 gatctgctcc tccaagaacg tgcgcaacgc cttgacgctc atgaacgtcg cgtcgagcac
    55681 ttcaccagcc tgcagagcga ccttctcctt caaaacggtg gtcttgccat cggcaccgac
    55741 gaactcaatc ttcgccgtcg tcgcggccgg aatcgtcatt gacttctcat tcgaacggaa
    55801 gtctccgcct ttcatatgag aaacatgggt cttggaatcg ggactccagg gagacatctt
    55861 atgcgggtgc ttccgggcat aggctttgac ggacaatggg gcgcggcgat cggagttgcc
    55921 ttcgcgcagt accggattga ccgcgctgcc tttgactttg tcgtagcggg acttgatgtc
    55981 tttctcttta tcgtccttag gattctcggg atagtctggg agcttatacc cctggctctg
    56041 cagttccttg atggtggcca cgagctgcgg aatagaggcg ctgatgttcg gcagcttgat
    56101 aatgttggct tcgggggtct tcgccatctc ccctaactcg gcgagggcgt cgtgctgttt
    56161 ctgttcggca gtaaggtatt ccgggaatac tgcaatcacg cggcccgcaa gagaaatatc
    56221 gcgcaactca acggtcacgc ccgccgcttt cgtgaatgca ttgatgatcg gtaaaaacga
    56281 ataggtcgcc agcattggcg cttcgtcggt cttcgtatag ataattttat ctgcttttcc
    56341 cattgggctt ctccctttgc tgtattgttt agttcaaagc attcaacgct gatccggcct
    56401 tgaaccaggt gatttgctga gcggtcatgc tgtgattcgt ctgaatcctc agatcaccac
    56461 cagtcttatg aatgaccact gtcacgggct tgccgggcgc caaattggcc aggtccacga
    56521 cgctgatacg atcgttttgc tcgatctttt catagtcctt aggatcggca aatgtgagcg
    56581 ggaggatgcc ttgcttcttt aaattggttt catgaatgcg ggcaaagctt ttggtgataa
    56641 cagcccggac attcaagaag cgtggagaca ttgcggcatg ttcgcggcta ctgccttccc
    56701 cgtaattctc gtctcccacg acaatcgatc cgatgccttt ggccttgtag gcgcgtgcaa
    56761 tttgggccat cgtaagattg gattcaccag tcagcacgtt ggttccctta ccaggctccg
    56821 acgaaaagct attattggcg cctaaaaaca tattgtcgct gatcttgtct aagtgaccgc
    56881 ggaacttgag ccatggccct gccggcgaaa tatgatctgt cgtagtctta cctttcgtct
    56941 tgatcaggag cggcaacttc tcgaagtctt taccatccca cttcgggaaa ggctgcaaca
    57001 attgcaaccg ttcgctggtc ggcggaatat ccacggtcag gttcgagccg tcctctgcgg
    57061 gcgctacgaa tccttcttca cccttcgcaa atcccttggc tggtaattcc tccccaacgg
    57121 gcggctgaag cttaaactct ttcccatctg cccccttaac cgattggttg actgggtcaa
    57181 aacccaaatc accagtgatg gcgtaggcag tcacaacttc gggactggcg aggaaagaca
    57241 gcgtttcgct gatgccgtcg ttacgtccgg ggaagttacg attgaaggaa ctgacaatgg
    57301 agtccgcacg acccttgact ccatctgacc gcttccactg cccgatgcag gggccgcagg
    57361 aattagacaa cacggttccg ccgagctttt cgaacgtatc cataaacccg tcccgcttca
    57421 tcgtgtgata aatgcgttcg gagccaggag agatcagaaa tgaagccttc gccttcaagc
    57481 ctgccttcaa tgcctgttga gccacgtggg ccgaacggct gatgtcctca tatgaggaat
    57541 tcgtacaact gccgatcaac gccgccttca gttcaaccgg atatcccttt tcctgcgcct
    57601 cagctttcaa ctttgaaatt ggccgcgcca gatccggggt gtggggaccg acaacgtgcg
    57661 gctccagctt tgacagatcg atctcaacaa tttgatcgta gtatttttca ggtgactgag
    57721 cgacttcagg atccgccacc agcagatctt tgtgtgactg cgtgaaggtg gccagatcgg
    57781 cgcggtcggt aatcttcatg tacgccacca tcttctcgtc gaacgggaag acggaggtcg
    57841 tcgcgcctaa ttctgccccc atattgcaga tggtgccttt acccgtggcg ctgatggttt
    57901 cagcacccgg accaaagtac tcgacaatct tgttggtgcc gccttttaca gtaaggaggc
    57961 cacacagata aagaattacg tctttggggg aagcccagcc attcagcttt ccggtcaatc
    58021 gcacgccgat cagtttggga tgcagcactt cccagggaag cccagccatg acttcgccgg
    58081 catccgcccc accaacaccg atcgccagtc ctcccaagcc gccgccgttc ggggtgtgtg
    58141 agtcggtacc aatgatcaag cagccgggaa acgcgtagtt ctccaaaacg acctggtgga
    58201 tgattccggc gcctggcttc caaaacccaa tgccatactt ttttgcagct gaggcgagga
    58261 agttataaac ctccttgttc tcatcgagcg cgcgaaggag atccttctcg gatcccattt
    58321 cggcacggat caaatggtca caatggatcg tactgggcac cgccgccttt ttcttgttgg
    58381 cttgcatgaa ctgcagcacg gccatctggg cggtggcgtc ctgcatggcc acacgatctg
    58441 gccggagggc cagcatcgcc ttgccacgtt cccaattctg gctatcaaaa ttgtccgcgt
    58501 gtgagacaag aatcttttca gcaagcgtca aaccacgacc gaacttcttt ctagccttgg
    58561 caaaaacctc cggcatcttg gcgtagagcg ctttggcgag atccatggac atagtaggtt
    58621 ctccgtctgt tagtacgatc tataggttgc gcgactcgtt cgctgcgaag gaggttgtct
    58681 agcaggatcc ttttcgcaaa caacacgtca cgttttgcgc tacttcagcg gcggcacttc
    58741 gcggcgtttg ggggccgcgt aattcaccag ataatcgaac aaccgaatca agcggctatc
    58801 ttgccgcttc tgatccaccc agtggccaat caagccaatc gtgcgagaaa ggatgaagaa
    58861 tccgttcaaa ctatcaaccg ggaacccgat atcgacgagt acagccgcca tggtcccgtc
    58921 gacgttcaga atgagattat cctttttcac cgaagtgatc ttctccacct caagtgcaaa
    58981 atccaaacaa ggcgtcttga tcttcaggct cttaacataa ccaaccagtt ccttgacccg
    59041 cttgtccgga ttacgcaggc tcttgacacg atggccgata ccaggaaccg gaccatgatt
    59101 cttcttcata taggctaaga attcatcgac cgacatcttg ttatcgactg cgtacttaaa
    59161 gaagcgaccg gcatcggtca cggctccgcc aaaacgggga ccaatcataa tcatgccggc
    59221 tgccactgac tgggaaaggc cgatgccggc acaggcggca agaatcgtcg cgtaggcgcc
    59281 gcttacgcag ggaccatgat ccgccgagag catcataatc cgcttaatga tttcggcttc
    59341 ctgcttcgag atcaagcgtt tgtcccacaa gagtccgatg acgtgaggga tttcatagcc
    59401 tttgttgata agttcggagg caggatagcc gtcgtagcac ggttcatcgc cacggtcatc
    59461 gctgattgtc gtgcgaatga gtggcgcaac catcacttca tcggccttca ttgcttcttc
    59521 aacggtcttt ggtaagcgag gcagaaccgc cggctcgact ggcgccttaa cttggccgga
    59581 cttcagcagg tcctcatacg tttccttaat tgcgggacca agcgcgccaa aggtaggggg
    59641 cacaagtgct cccgctttct tgagggcatc ggacttcgac cgagcggacc cttcgccttt
    59701 catgccttcc ttggcaccgg catggccgaa tttcattcct ttgggcaaac tctcctggca
    59761 gaatccagat accacggcga tcaacttcac tcgccgcttc ttggccccat accattcagc
    59821 tgcgcgctcc tcgaggtcgc cgcccatttc gcccacaatc acaacggctt tcgtttgcgg
    59881 atcgttttca aacatctcaa ggtagctgac gtaatccgta ccagggtagg catcgccacc
    59941 gatcccgatc gccgtcgtaa tgccgtcggc gaactgcgaa cagatccaaa tgatttcatt
    60001 cgagagacca ccagacttgg taatgacgcc gaacgatcct tctcgataca gcttcgaaag
    60061 gacgaggttg tcaaatgcac caccaatcac accaagacga caggcgccgg ctgaaataat
    60121 accgatagag gatggaccat tgaaaacctt acccagcttg cgcgcatggg cgccgagaat
    60181 cttcgcgtcc ttctccggca caccctcagt gatcattgag accaccttga tatgcgaatc
    60241 atcaagcgct tccattccgc ccttcatcgc acggtctgcg ccaatgtaga ccagactggt
    60301 attgagggtc gggtgattct tcgtcgcttc ggcgatagac ttgtagacag gaatcgcgat
    60361 gaggccgctg ccgtaaggta tctcattggt cttaccggcg tctggcggat acacgaatgc
    60421 ctcgacgttc agcggacgct tgatgagata acagaactcg gccatgcggc gggcggcgtt
    60481 gacaccggct tgaccaccct ggatcaccac gcgggtgtct ttgtttgcca gaatactcat
    60541 ctcgggatct ccccttatat tcagttggtc atagacggca ggctacttcg cttgaagtgc
    60601 cttgtcgacg atgtcggtaa gcggtgtgtt gcggtcgaag acattgatat caaagccctc
    60661 gtctttcagc gcgcgcatgg catcaaggcc ttctttttca cgcggcccgc cacgacgcac
    60721 ccaaatcttc acatttttga gcttgccttc cgactttgct ttcctgaatc cgttgatgat
    60781 gccgccgaat gtctttttta catcagtgaa atttgcgatg gcaccaccta cgatgatgtt
    60841 tcggatacca ggaagagagc agactttctc ggtgagcact tcaacggccc aatcgggtgg
    60901 atctcccgag tattccgcat agtttgccaa cttgccgcct cgagcgacga cagcatcaga
    60961 gtaatagaca ctggcgcccc cgccggcagg caacatggcg gtatcgcccc cggggatttc
    61021 gatgaatttg acggaccctt tgatcttgct atcgacggcc atcacctcaa gctcttgttt
    61081 ggaatatgct cgcccgaatt ccgcggcaaa ggcaaagttc caatcagggt gcctgaattt
    61141 ggcatcaccg tcgagaagcg tgactgcatc cagggccacc agttcatcat cgccggctcg
    61201 gagaactacc ggattcactt caagatattg cgcgtcttcg ctatcgaagc aggcaaacat
    61261 tttcccagca aactccgcca ttttcttggc aagcgcgccg gagaatccgg cttctttgct
    61321 gagcttttcg agggattcgg gagagggaga ttgcccgatg tcgaggcaca aacgtttgac
    61381 acgttcccag ttagattcaa cctcaattcc gccacaattg gctacgagga tctcactgcc
    61441 ttcgcgtgtc gatttcacag cacaatagta ttcttccttg tgcgggatca tctcagagac
    61501 aatgacctgg gtcacagtga tgctgccgac ttggcgacca atcatttcct tggtcgcagc
    61561 ttccgcggcc ttaaaatcta aatcgacctt gaccaatccc agtttaaaac gcgagccgag
    61621 cgcttcatgc gctttggcga ccaacttcga cttcttcaac cattcattgg cttgccccaa
    61681 tttggtcagt tcatcaactg aagtgacgac cacataatta ggaacgttga ttccccactt
    61741 cttcatcagc cccatcccgg gaccttccag cactttcgcc atgattgacg actccttggt
    61801 gtgtgatagg gcagagaaac ggagcgacag agtaccgaat tctgcggatt agctcaatcc
    61861 tccaaagggc ctacgcttcg agctcagaag tcctaccata atgggcactg aagattcatt
    61921 accataaatg attgataagc ttaaattgtc tccttagtta tctgaaagaa ccgagacgga
    61981 ccttccgatg ctaaccaact tgcgggcgac gaatgcgttg gcaccgagga caataaaagg
    62041 aacttcgctc gccgatggat cgcctgatca ccgctccaca atcgttcgga caaggctcgc
    62101 ctgatttggc atagacaagg tgtcgacgct tatactgccc ctctgttcca tccggcgcaa
    62161 aataatcgcg cacactggaa ccacccagat caattgcctc tcgcaagacg tcccccatga
    62221 tttcatgcag ccgtatcgct gccttttggt tcacttgatt agcaatttga tctggatgaa
    62281 gtcgggcacg aaacagcatt tcattggcgt aaatattccc aattcctgcg atagcctgtt
    62341 gatgcatcaa caggggtttc agcctactac gcgtggataa aagcaactgc acaaactgct
    62401 tttgacttat cactaaagga tcgggcccaa aacgacggga tgtatatcga tcaagtccag
    62461 cttggtctaa taacgagaga cgtccgaatc gacgtggatt ccaatatcgg atctccgatt
    62521 ccgcgcctcc ttcaagcttc aggacaaagt gcgtatgttg cgggtgttta gtcggcgtat
    62581 tccgaaacaa gagtaggccg gtcatcccca attcggcagt cataaatttc acttctgctg
    62641 cgcggataaa agcgaggatg acgcttttcc ctcttcgctc aacccctgta atcgttgctc
    62701 cgcgaaacca ttccaaggaa gacaagcctt cccgcacaat gtcttcccgc cctacccagc
    62761 aatcactcac cagggctcca accactctct cgcgtagctg gcgcgcagcc acttcagctt
    62821 ccggcaattc aggcatgtat aggtttccgt atgtaggtaa tgacacaaaa aacagtaaat
    62881 tacgccatgg cgacaaggag aaatgcaact cccaacagca gttcctttaa accaattggc
    62941 agcgtaatag atgcgaaagg ggggaggcct gtagtgaaag gatgctgcta ataatgtcgg
    63001 gggaatcaat ctaggagaga gaaggtcgct ctacagcaca acgtcggcgg aaaacgtcct
    63061 cgatcacctt atcgaggcga ggtagcggca taccaccagg acgccttgtg agggcaagct
    63121 taagtgcatc ggaatacgtc atcccctcca cgcaacaaag gtaggcgatg acaacggaca
    63181 ccgaacgccc cataccagcc cggcaacaga ccatcaaccg attgtcaggc aggtgctttt
    63241 caatccattg cactgcgtcg tagagggctg acaccgctgg ctcaccaaac tccttcaggg
    63301 gaatcttggc atagatgatc cttgcgggga cagtcacatt ttgttcttct gccaccatga
    63361 gtatcgctcc gacctgcggc ggcgggttct tcgcatcatc agcattaccg acgagcagac
    63421 gcttattgat catgtgcatg gtgaggttag tatagaattc cgcgggaggg ggtcaaggat
    63481 tcctgcgatt ccatgcccaa cgattgaaga ttccgtaacg cagtgcgtat actcattcaa
    63541 ccacttggct gatggggtaa taacgatggc tcttattcag cttgaacagg tagaaaagcg
    63601 cctgtccagc gtacaatgcg cgatctgcaa gacaaataca ttcggcattg atcggcggac
    63661 tctgcaatcg gacggagaat gtcgtggggt gtgcctcaaa tgccgctaca gctttccggt
    63721 atataccgac atggaatttt atctgcgaac acaacctgat attccttacc ggctcaagga
    63781 aatttcttgt ccaaattgtc aacatcgtgg cgtatctctc gacttccgca tcacgatgtc
    63841 tgtccgtgag gcaatctatt tcgtgacgtg cagcgcatgc cacactcagt ttcccgagcg
    63901 ttcttccctg gaagcttttg aatagccctc gcccccggca tttcgtgtat actgacttat
    63961 tatgaccgac acacaaaagc cgaaaccgcc cctccctgtc gctgatgtcg caccaaagcc
    64021 tcgcaaagaa attcctctcg tctcggtgcc caacgatcgg gacatgattg cggaggaaat
    64081 ggctgcactc tttgatgagg atcgcgtgtc tcatcagcac ggctcctcag agcctgaagc
    64141 cgattagcgc ttcacgccgg ccgaatgact tccgccactc cggaggaaag aattcgaccg
    64201 accatggctg gccggccttt ccgttctttt cggacgatct cgtcaacgcg aacgattgcc
    64261 ccacgatgcc aattgtcgaa cgtggcgtta gtggttgatc tctccttatc ttgtcgacca
    64321 acttcagacc tacccgtctg atcgcacaac cacacccgtt tttccccctt catctcccgc
    64381 aactcgctta cgacgcggtg ataatcttgc tttcgaggca ccaaggactt cccatcttta
    64441 cgtatgatga cataagaaaa tttgagagcg tccttaataa atcccacttc gcgatcgatc
    64501 tgactaatcc aggaaggagt ttgccactcg cgctcttcat gacaccaatc gtcaggtttg
    64561 agcaacgcgg gacagagttg gtcatggagg cagggactgt agatcgagca ttgcaattca
    64621 gacagcacat tatccctcac ctgatgcagg gcacgcgatt cagccctcga tgccggctca
    64681 atgagcatta ggcttccgtc ttttgccaag cagtctacca ggtgattgat cagtgttgtc
    64741 cgtcgagcaa tacaatcgga tttttcggca aacagttccg aaagcacatt ctgaacaatg
    64801 ataaggtgat aggcattttt ctccgctccc attcgaagaa ctggaggaaa ggagtgctca
    64861 agatcgcaca cggcagtctg caatggttga atagaaggta tgttgatctg cctggcgtat
    64921 tcctcccaga gccgggtcga cagtttcatg gcctcgatcg aacggtcaac caccgtcatg
    64981 cggagactgc ttatgggtgg caaagactgt gaactgcacc agtcgagaag ggctagtgag
    65041 ccggtgccag gtccgccccc gacatccaac actcgaaatt cttcatttgt acgggatgga
    65101 agtagcggcc gcaattcctc caaaagcatc tggatcttgc cgacgttaac aggcacataa
    65161 taatgaaggt agctggcacg tagcgcccca tcttcaagat aggctgtcgc accagctttg
    65221 gttcctctcg taaacatttc agaaagattt ttcacgccac tgactagcga tgctgaaagt
    65281 gctggattct gtagggagtt attgacccta gccaccgttg cgattgtgcc taacattgcc
    65341 gatgacagtt ggtacatgga gtcggcctct tggttgaccc tctaaagacg gctgcggtat
    65401 cttggatagg agaggagtac ttcacatgac tgaccccatt ttgcaagcct accgagaggt
    65461 agaaatggcc atggagcgct ttacgctggt tcttcatgac catgtcgatt atctccgcaa
    65521 gaccgaggcg cccggatctg ataagctgca tcgaatggcc agtggcacca aagccatgcg
    65581 tgacagcgca tccatttatt tgtcgtacgc aaaatacgtg gctcacggta tgccagaaag
    65641 ccctgatctc gtggaagaag atcttcaggg ttaatcgctt ggaaccaaaa aatgcagagg
    65701 gcccgttcgg gtcaaccgaa cgggccctcc tatctgacga ggattacgcc gttaatcctt
    65761 agatgctgcg catgaaatgc cccatggctt cgtgatccgc agccgaggcg cccatcacct
    65821 gagaaatcgc tacgttcgtc gacttctttc cagttagccc tgattcaact tcgtcaacga
    65881 tcaattctac cggcatggat tgaccaccat aaacccgtgg tccaccgata atcttcgcat
    65941 ttgagaagcc atagatggct gtcgccactt cctttgccaa ccatccgacg tagttaaatt
    66001 ccggcacgac aataagcttg gcttttccac agagcttacg caactcttga gtggggaagg
    66061 gacgaaggga tctaaccttg atcaggccaa tcttcatacc cttttcagcg caaatgcgga
    66121 cggcttcgcg agattgagcc gctgcactac ctgaagcaat gatgatggcc tcagcatcct
    66181 cgacattttc agccgtcagc agcccgccca tgtactgatt aatgtacttt cgagagcgct
    66241 cgaccgcagc ccacacttcc tgttgccaga cagcgtgaat gttgtaagcc ataaaatttg
    66301 acttctgaac gggggcatcg cgagaaagcc gggccggagg attctcggca tccaacactg
    66361 gcacagctcc acgccaaggc tcacgcggcg gaagcttcat accacgatct tgcatgcgca
    66421 catagcctct cgcatgcgtc acaaagaacc cgtcgcaaca cacgcccaca ggaagagtca
    66481 catcattttt ttcgctgatg acaaatcccg ccagcgtaaa atcatacatg tcttgctgat
    66541 tttcagcatg gaacacaatc atgccgcaat tgagcagata cgacacttcg atattgtcag
    66601 gctgaatggc caatggtgcg ttcacgactc gacaggtgaa catcgccaca acgggtagcc
    66661 ggtgaccggg ccatgacgcg ataccttcaa gacctctcaa agtcccagga cccgcagtgg
    66721 cggtgtagca tcgaacgccc gctcgcgaac cacccgcgat agcggccatg acgccaactt
    66781 cttcctcgcc acggtaatat tccttcacat acccctctcc atacagaaca ccgacgagct
    66841 gcatggtttc actttgcggg gtaatcggat aggcgatagc gaggtcaacg ttggagcgac
    66901 ggatggcttc ctttgccgcc tcgctgccag taataaactc tttggtccgt ggagcttcca
    66961 gaaacatata ttccggcgtc acaaccttct gttgctttgc cgccgcatga gggtctttct
    67021 tggtctctac tttcgcaggc gaaacgctcg tggctggctc gctctgggga ccggtctttt
    67081 gtgcttcgct catcatcaca cctctcgact tattgcctta gcctaaaccc ctagccttct
    67141 cgcttcatct gatcaggaga atgaccaaac gcggcggcac tacctgcacc ggcagcggaa
    67201 ggcataaaag tcataggatt tgtatgcgtc ttgccatcgt ggactttcga ctgagtgcca
    67261 gtgaagcgga cattctcccc attgtcaggc aatttaatgc ccaattcttc acgaaccttt
    67321 ttgaagatct gcgcagtctt tttcagcttt agggtgtcgg agtctcgaat cgtcagcatg
    67381 gcgtcttcat ggccctgttc tgcgcagata gccattgtgc agcaattcgt ccctgcccgg
    67441 atcattttga gggtcagatt ggcgtaatga caatgcacac caataaagat acaagcctcg
    67501 atcttgttac cccaaattgt aagattggga tgattcggat tgattacctc ttcaggatcg
    67561 atctttggat acttggggcg ataatcaggc atgggaataa tcatgacgtc cgggatctgc
    67621 gccgcgatct ccagaacggc cttggctttt tcgactgcat ggttgttcca cgcccacaag
    67681 acgagaggtc ctgggaagat cgttgcattc gggctcgtca gcattttccg agccatttct
    67741 tcgatcactg tgtcttcatt aggttcgagg aggccgtaat atagtccttg cccaggatca
    67801 ggcaacgaca ctcccatctg tgctgctgac ggtggatgga accctgccgg ccctggcacg
    67861 ataatccgct ctctcgtatc ttgcgtcgtt cccacgcccg ttcccctttc gtccaattac
    67921 ccaactacag ggctgaccaa tgtcgccgtc gtactttttt ccccataggt aatattgtcc
    67981 gtcaatgccg ccaccggcaa ctggtcaatc ataatcattt taatggcatt atttttggcc
    68041 atattgtcgc agacccacac acattgcgcg cagcccttgc accgatctac ggccacataa
    68101 gctgagccat acttaaatcc cttgtccttg cccatttcgt cgctgtaaag aatggtattg
    68161 gcttccgggc aatactgtgt gcagagcttg caactttttg cggcacagat ctcaacacta
    68221 atatcggcta cgagatacat gagaactcct tgtccgtgat ccggattacg ccgtgacgct
    68281 ttcggtcgct tccgaacgtt tcacggatgg tgcggcccat ccatggtcaa cagcataatt
    68341 ccagcctgct cgaataacgg ccacattttt ctcaatcaat tcttgcttct tcttaaactt
    68401 tcgctcgacg acgctatcca aggccgcggt tccaccggat acgacaaaac cttttccgag
    68461 gaatcgatcc ttaacggact gctccagtgc ctcgactgta gtgagaccag taatagcgcc
    68521 gatacaaccc atcaacgcca tattcgtagc aaggtccatc cccgcaacct caagcgaaag
    68581 cttggtagca gggaagtagt agagcttcgc atgccgctct tcgagttcgc gagcctgatc
    68641 gcggtgcaat ttcatcgggc cgtcattatt gatcaaggcg ataccattct cttttaagcc
    68701 gaaatagaat ggcatcgtgt acgacttacc gtgcgtaata acctgggggt gaaagatgat
    68761 aatgatgtga gggaaagtga tttcgccaat ttcataaata ggctcatctg aaaccctgac
    68821 atagctctca accggcgcca tgcgcttttc tgacccataa aacggtacga ttgtactctc
    68881 gccgccggca tgaatgaccg ccgtgctcag aatgtgcgag ccggtcacaa cgccctggcc
    68941 acccacacct gccatacgaa tattgaaccg tgtcgccatg ctgaatcctc cttaaacgtt
    69001 gctcaggcct tcggcagacc aggagcggga gccgccggct tcgggaggaa ctccttgtag
    69061 ccatagcgct ccgtgagaaa ttgctttgct tcgtcggtaa tgtattcgga gaactgatag
    69121 cgatcgtttt caacgttctt ggcgtcttcc atgaccttgt cggttggaat ggcgtattcg
    69181 atgttgcagg aggtataggc ttggatatac gtcgacccga cctctctggc gatcagcaca
    69241 gccttcttaa tcacgctctc aacgcggcgc ggattgttcg ggacaaccgt ggcaacgtac
    69301 gcgcagccgg cgaccttcgc catctgcaac atgtccattt tttcaaactt tttccccaac
    69361 ggagccatct tcagcacggc gccacgattc gtcattccgc tttcctgccc accggtattt
    69421 ccatagactt cgttgtctaa cataatcgtg gtaaagcgtt ccttccggaa ccaggagtga
    69481 agaacttgct ggaatccgat atcggccgta cccccgtcgc ccgccatcac cactacgtcc
    69541 ttcggcttat caccaaaacg aaggcgcaac cctcgagaca agccactcgc cacaccgttt
    69601 tggtcaccat agttaccgta cacaaagggg atggcagctt gcgagattgc caaacgtcca
    69661 cagcccgctg ttccaacagt gatagtatct tcgggattcg ggaatgcgat catggcaagg
    69721 cggataaaga gggtcatggc acatccagcg cacatggggt gctcttccag cacttccttg
    69781 aaggacccca tctgcgaaac agagaccttt ttcccaaacg ggccgtgctc aaccatgtct
    69841 cgatattctt tcggcatgaa cttttcaaag ccgctcgaga acttgacgta atcaagactc
    69901 ataaggattc cctccctttt atgctctggt gactttcctc cgtcattcca aaatggccgg
    69961 agaaagccaa gcgcaaatta tatcgacgtt gttcgaacta agtactggac tgtgttcctg
    70021 aaacggaaag gaatgtcgac ttacgaccta actgtctgat gccgccgagt gtaacaaagc
    70081 gcaaaaaaat ctgtcaatca agtcggcgct agaaattagg aagaaccctg tcattccacg
    70141 gtaacggcaa gtctatagag tccacaaaag cattgcaact ttgcagaagg cccacactga
    70201 acgaaagaag gcctagtgga tgccgccttg ctaggccctt ggccctaaat ccgcttgaac
    70261 tcaaagattt tgagcaaaga acaaacatga aataaggttc aattcagttg cagttcatct
    70321 gagaagcgcg taaaaattat cgcttaacac gataggcctc ctaacatcta tggcgatacg
    70381 agttctggta ccaggggaag aacagggtga tcaacgtgtc ggaggcgtgc ataagcgccc
    70441 gccgatccca gacggctccc ttaaggccga gtgcccaaaa ttcatgagcc acggtccttg
    70501 cggaggggtg cgcaaaggtg ggttttgcga agtctatccg gacatgacct gtccgtgggt
    70561 cacactgtac aacaagctca atgagctggg tcagttggaa tggatgaaac aggtatgacg
    70621 attgccggta aggggtgatg gtgtgagaga acagaacaag aagaaattga agacaggaaa
    70681 ctccacaacc aagctcggct ataacgagcg gcacgcacgc agcgggatct cggccccttt
    70741 gccagacatt gaaacctttc caaaccagta caagggctat gaaattacga ttgtcattcc
    70801 tgaatatacg gcgatctgcc ccaagaccaa tctcccggac tttggaacga ttactcttca
    70861 ctacaaaccg aataaacagt gccttgagct caaagcactc aaaatgtatg tccacgccta
    70921 tagaaacatc ggtattttct acgaaaatgc cgtcaaccgc atcctccaag acgtggttcg
    70981 ggcctgccga ccgacttggg ccaaggtaac gggtgagttt gccgctcgcg gagggttgcg
    71041 cagcgtcatc gaggcaaaat atcccgaata gcccgccaac tatccactga tctttcgaca
    71101 ttccgccccg ctgtacctgc tcctcctggc cgattccgag cagctcctca gcacatcgca
    71161 tcacgccccc cttcttcagc aaccgcgctg atcgcccttg ggcctaaagt ctcgcttcga
    71221 atccaccgac atcggacagt caaggtgtag gacgggtgcg aggtcacgcg accacgctcg
    71281 ggcatgaaag ggtgccgttt tgattacgcg ctccgcaaag gctgtcattg tccgactgac
    71341 gatgacggtt ctggtcttca ttgtaggaat gtacgccgtg tccgttccca ctgcagacgc
    71401 cattccatca tttgcccgca agtatgcact cgactgcacc gcgtgccata cagcccctcc
    71461 acgactcaat acatttggcg aacgcttcct cgaaaatggc tatcagctcc cgggcaccac
    71521 agacggcggc ctaacgggaa agaaaaatct gggggatgtg agcctggacg atgttgcgaa
    71581 ctacaccggc gtccgcctgc gcggtaatgt gctccgcacc catcacttca aacagcaaaa
    71641 tccatccggt gcagaggcag gcacggtcca aaacaagagc gacctggcct tccccgaagt
    71701 gttcagcctc tttaccgccg gcaccttagc gaaaaacatc gggttttttg ccgaactcga
    71761 atccaacctc gaagcatctc acaccggaat tgagcgggcc ttcctcacct tcaacaacat
    71821 cggaggtgaa aacgtcgcca atatccgcgt cggaaagatc gacccatccg cagccttttc
    71881 cttttcaaca ctgcgccaac aactggactt cattgcggaa agcacgcacc cctcgacaaa
    71941 tgccgttcaa cgcgcgggat tgtttccgct ggcaacggca gccaaatttt acggactgcg
    72001 gaacagatcg gggggcacga tttctcccta tgccccttcg ctctataacg cagtggtaga
    72061 gaccggcgca gaggtacggg ggcggccctt cggagattgg ttcatgtacc aactcggcgt
    72121 gctgaacgga gccaatgaag ggttcggcga ttccaataaa ggcaaagact tctatggagc
    72181 catccggttc gattacgcac gctcagcaaa tttttcagcc agcctgtcag gatttgccta
    72241 tctcggcaat agcaatgcga ccgtcttcga tgggacacga acgacggatg tgaactggag
    72301 tcgctacggc gtcgcggcac acctgcgata caaaatgttc gatctgcacg gaatgtatac
    72361 gctcgatcga atcacgcatg caccagcgac ggctctcagc aattttgaca cggacgccag
    72421 cgggctcacg gtcgcgctgg atacgcacgt ggcgaacaat acgctgcttt cgttgcgata
    72481 cgacactatg gatgcggggg gagacctcag ccaacgaagc tctcaaagct tcctcggcgc
    72541 ccaggtgaag cattacgtgc ggtcgaatat cgcactgtat gcgcgattgg accacaatct
    72601 gcgccacgcg gaagacgggc aagcggcagc caggaatctg cgggaagcct tctttgccgg
    72661 aattgacgtg gcctactaga tcggcaggag acgaacattc gccatgggca tcagcatgta
    72721 taaatacctc gtcatcctcg cggtcagcgg gctctgcgcg acgagcgcct atgccgttcg
    72781 gcctgaagac aatcgggaca cccttgcgga aggccgccgg atctatgagc gagcgtgtgc
    72841 gtggtgccat gggaacggag gcttgggaga tggaccatcc ggttggtcca tcggccgtta
    72901 ctccgcccct cgtccacgcg acttcacaaa agaaagctac aaactacgca gcacaccgtc
    72961 cggcgaattg cccacagatc aggacctgtt caggactctc acgcaaggaa ttccaggggt
    73021 catgccatcc tatcgctccc ttaacgagtc agaacgatgg caggtcattg cctatctcaa
    73081 atcattcaac cctgccttcg agcaggaaac gcccgtatcc attcctctac ctcctccccc
    73141 ggtctcacga cccgagggcg cggtacagca tgggcgagtg ctctacgcaa agtacgactg
    73201 tcgggtctgc catggagcaa acggagaagg aaatggaccg gaatcgcagg ccggacgcct
    73261 tcgtgacacc aacaatctgc ccatacgcgc cacgaatctc actgatccgg cttcattcaa
    73321 gaacggcagc acggcacaag acctctatcg atccatcatg actggcctcg acggcacgcc
    73381 aatgccctcg tatgcgaacg agtttgccgg acaggaagag gcggtttggg atttggtgtg
    73441 gtacctccaa tccctctcag gccgttcgga gaaatgagtc acgccgatga tcatcacgcc
    73501 atcgagcgca acgccttacg cgcaccgcac agccggcgaa gaaaggaacg gccactcatg
    73561 gtgatgaggc tcatgctggt agtcctgggg ttgaccctgg gagttccctc tttgctgcag
    73621 gccgaaagcc cgaccggcaa gttggccggc aggattacct atagcgggtc ggccctgcct
    73681 gaccagacgg ccgagatcac tcgcgattct gcattttgcg gaacaagcac cacgatcaaa
    73741 gacgtcgtga tccatccaaa gacgcgcggc cttgaaggcg tcgtcgtgag catcgagagc
    73801 ggcaaccttc cctcaagcga tgcccctctt gctccgctcg tcctgacgaa tacccactgc
    73861 gcattcctgc cacgcacggt cataggacag gtaggccaac aactggagat ccgcagcgac
    73921 gacccggtca tgcacaacac gcacatctcc ctgggatcac gcacctttgt gaatgtggcg
    73981 atgatcccgg ccagccgacc ggtacgaaag cctctcaagc aacccggcat ctatacggtc
    74041 aaatgcgacg cacacaaatt catgcatgcg gatgtgatcg cctttgcgca tccatttttc
    74101 agccagacag atgaaagtgg ttcatttcag atcacaaacc tcccaccggg tgagcatgtg
    74161 gtgaatatct ggcatcacac gctgggaagc tatcaacaaa ctgtgcgtgt ttccgctgag
    74221 gcagagacga ccatcgcctt tgacttcgcc gctcatgctg aatccaacaa gaaataagat
    74281 gccctggttt catcacctct ggatgatgtg gcaagggagt ctccggctcc ggctgagtgt
    74341 ggggatggcg gtcctgatca cccttggcat gacggtgttc gccaccatcc gactggtaga
    74401 aatccgtcac tccctggtag acgccgcgca agcccgcgca ctggcggtca gccgcacctt
    74461 cgccatgatg ggagcggccg ccgttctgga caatttgttt cgcattcaag aggctctcac
    74521 ccgatatgcc aacgaggcgg acattgtcgg catcgtcatc atcgatcccg acaatatggt
    74581 tgtcgccgcg acaaagcctc acgatatcgg ccgggaactg accgatcaca ccctctctct
    74641 cgctcaaacc tccgggtcgg agacaatggc ccatcgcctg agtgaggacg gaaccccgac
    74701 gctgatcgtc gtcaccccgc tcaagaatga agacgacatc gccgcgtggg ttcgcatcga
    74761 attttctctt gcggcaatgc aaggcgagtt ggtccgcgaa gttcgtcgtc tgttagtgct
    74821 ttccgttctg ctgatgagcg tcacgattgt ggtcggacaa atcggcatca ggcgaatgtc
    74881 tgccctcttt cgagacacgg ccgcgaaact gcaggatacg ctccatacgt tgcaccgccc
    74941 cttgaaagaa gacgcaggaa acgcaacgtc gcttaacggc gactcgcctg gccccgcgtc
    75001 ctatacaggc gaactggagc agatggtcga tctggtggaa acgaccaccg ccctgcttag
    75061 gacccaagcg caacggctac agtccttcac tgactcgttg gaagacgccg tgcggcagcg
    75121 caccaccgaa ttacatcaag cgaaggacgc ggcagaaacg gccaatcaag ccaagtcaca
    75181 attcctggcc aacatgagcc atgagatccg gacgccgatg aacggcgtct taggcatgac
    75241 ggagttgctg ctcacgaccg ccctcacgcc gaagcaacgc tccctcgcga aaacgcttca
    75301 ccagtccggg accggcctcc tggacatcat caacgaaatc ctcgatttct ccaaaattga
    75361 ggccggcaaa ttgaaactgg aatgcattga attcggcttg cggcagacgg ttgaggaggc
    75421 gattgatcta gtggcagaaa cagcccaccg gaaacatctc gaactgacct gctttatccc
    75481 cgaggagatt ccggatgccg tcgtgggcga tccggtccgg ctccgccaga ttctgctcaa
    75541 cctcgtcggc aatgccatta aatttactca ggccggcgac gtatcggtca cgctcagcct
    75601 ggtttctcag gaagcctccc gcgtgaacct caaatgctgc atccgggata cgggggtagg
    75661 gatttccgac gaggccaagg cgcgactctt tcaagcattc tcacaagcgg acgggtccac
    75721 gacgcggcgc ttcggaggca caggtcttgg gctggcgatc gtcaaacaac tcgcccactt
    75781 gatgggaggc gacgtcggcg tcgatagtat tcccggccaa ggatccacat tctggtttac
    75841 cgtctcgatg gaatacgcct cacaagctgt ctccgcccat gaaggcctgg cgtcaccgct
    75901 ggcgggccac tcgatcctgg tcgtcgacga caattccact aaccggcaca tccttgaggc
    75961 acacttatcc aactggggag cgacggtgca atccgccgcc tcgagcgaag atgggctgcg
    76021 cctgctcacc gaggccaaag gcgggaatca gaagatccag atggcggtgc tggacattcg
    76081 cctccctggc atgaacggca tcgaccttgc ccggaaaata cgggaagacg tagacctgcg
    76141 cgacatggcg atcctcgccc tgagctcaga ggatcgcgag acggacgaat ctcaccacca
    76201 tcccaagctg ttcaatgcgt ggttgagaaa acctgttcat cagtcattgc tgaaagattg
    76261 tctcacgcgc ctttgccttg cgccgtccgc tgaagacgct tctgcaacca ttcagcctcc
    76321 cgaacagacg agaacattgg ccgggcatat cctcctggca gaagacaatc ctgtgaaccg
    76381 cgaggtcgcg tgcacaatgc tcgagatcct gggatgcacg accgccgtgg cggagcaggg
    76441 caaagaggcg gtcgagacgg cggcgcatgg ggcatttgat ttgattctca tggattgtca
    76501 catgccggaa atggatggcc tgacggccac ggggctgatc cgcgcccatg aacagcaatc
    76561 catgccggcc cgacacacga tcattgtcgc gctcaccgcc aatgcattgg agggggaccg
    76621 tgagcgctgc cttgccgcag gaatggacga ttacctgacc aagcccttta ccttggacgc
    76681 gctgaaggag ctgctccaac gctggcttcc cgaacatgtc ccttccgact ccacttcaga
    76741 ctcgcagccg gccgaagtat cgaacggggt tccacctcaa caggccgttt catctcatgc
    76801 tcagcccttg gcagcagaga gcgagcatgt ggacgcgcat gcctgggaag ccattcgagc
    76861 ccgccagcga ccaggccagc cggacttttt acataaagcc ctttcgctct atctccccta
    76921 tgccgacaag cagatcgctc ggctagagaa cgccatcgcc gaccaggatg ctcgagccat
    76981 cgccacgatc gcccacacga tgaaatcctc ctcagggaag ctgggggcac aacgccttgc
    77041 tctcctgtat accgaacttg aatccgcctc acgcgcagga cggatcgggg acttccagga
    77101 actgtatgac cgcttgattc ctgagcatcg cgcagtctct gccttgatgc gggatgaact
    77161 caacggggaa ggacggtcgg cagcatgann nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    77221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    77281 nnnnnnnntc caacgattgt tgcattctcc gcagccggga gaagctcccg acgctcctct
    77341 cgagagcgaa caggtcatcg cccggcaaca gtacgagtcg agcctgcgtg agagcgaaga
    77401 gaaattccgg cgcctcttcg agtcttcgcg cgatgcgatc atgattctgt acccgcccaa
    77461 ctggaatttt attgcctgca acccggccac ggtccaactg ttcggggccc gggacgaggc
    77521 gcacttcacg tccctcggcc caggagatgt gtcgcccgaa taccagccgg acggcgagtt
    77581 gtccatggtc aaggcgcgca aggccattga ggctgccatg cgggaggggt ttcatctctt
    77641 cgaatggatg cacaaacggg ttggcggacc aacctttttg gccactgtcc aattgactcg
    77701 tatcacactc caaggtgtcg agggattgca ggccaccgtt cgcgatatta ccgaacaacg
    77761 ccgcgctgaa accgaactac gcgcctatgc cacttttcaa cgagccatcc tggaccatgc
    77821 cggctcggcg attatttcct gcagacctga cggcatcatt caattgttca atccggcggc
    77881 agaagcgctc ctgggttaca ccgccgacga actgatcgga cgtcaacatc cagggatctt
    77941 ccacgttcgc gaggaaatcg tggagcgggc cagacaactc tccgaggagt tcggctgcac
    78001 cattgcaccg gggttcgacg tctttattga aaaatcccgg cgcaatcttc ccaatgaaca
    78061 tgagtggacc tacatcagga aagacgggac caggcgaacg gtgctgttga atatcacggc
    78121 gctgcgtgac gccgacagca agatcacggg gtacctggcc gtcgcctccg acattactcc
    78181 cctcaaacgc accgcccagg aactcctgct ggcgaaagaa gctgcggagg ccgccagccg
    78241 cacgaagtca caattcctcg ccaacatgag ccatgagatc cggacaccca tgaacggcgt
    78301 cctcggcatg accgaactcc tgctgaccac cgcactggac acccggcaac gccacctgac
    78361 tcgcacgatc cagcaatcag gcgaagccct tttggcgatc atcaacgaca tcctcgactt
    78421 ctccaaaatc gaagcaggca aactgcagct ggaacggctg gactttgatc tccaggacac
    78481 cgtcgataac gccgtggaac tctttgccac tccggcccaa cgcaaaggac tggaactcac
    78541 gtgccacatg ccgagtgcga taccgcgcac tcttcgtggc gatcccatcc ggctgcggca
    78601 ggcgctgctg aacctgatca gtaatgcgct gaagttcacc tcaacgggcg aaatcaatat
    78661 acgtattgac gccgtggtcg agaccgacgc ctctgtcacc ctgcggtttg ccgtgaagga
    78721 ttcgggcgtc ggcatccccg ccgaggccca tcagcgcatc ttcgaggcct tttcgcaggc
    78781 cgatggcaca acgacccgcc gcttcggtgg cacaggcctc ggactgacga tcgtgaaaga
    78841 actggtatcc ctcatgcagg gacagatcgg cgtggagagc caggtgggcc agggctcgac
    78901 cttttggttt accgctgtct ttgagcgaca gcctgcgact accggtgatc cgtatccgga
    78961 acatgccctg ctccaacgac ggatcctggt ggtggacgat accgccgcga accgcgagat
    79021 cctggatgac cacctccgtt cctggggcgc aatccctgcg ctcactgcat cggccgccga
    79081 agcgctgacg caactccgcg cggccgccgc gaggcaacag ccattcgagt tagcgattct
    79141 ggatttccag atgccggaca tggacggcat gcagctggcg caggcgattc gggctgatcc
    79201 gcaattgtcc tcactccccc tcttgatgct cacgtccgtg gggtatgacg ccggagctcc
    79261 tggagtgccc gcggtcgatg gctgggtcac caaacctgtt cggaaaacct tgctgcaaca
    79321 ggccatcctg ggcctcttca ggacagggca gcgtgcagca atacgccggc cggatccggt
    79381 ggtatcggaa ccagtgacga ctgtctccca ctcggcacgt cttctcctcg tcgaggacac
    79441 accggtcaac cgggaggttg ctaccgggat gttggacgtc ctgggatatt ccgtgcatgc
    79501 ggtcgagaac gggcgtctcg cccttgaggc cgtggcacga gaacagttcg atcttattct
    79561 gatggattgc caaatgccgg aaatggacgg cttcaccgcc accgccgcta ttcggcaaca
    79621 ggagcgtcag tcaggtggag ggcatcgcat cccagtcatc gccctgaccg cgaacgcgat
    79681 ggacggcgat cgcacccgct gtctcgctgc cggcatggac gattatctgg ccaagccctt
    79741 taccgcggcg caactccgca caatcctgac gcattggctg acaccgccgg tggctgacgc
    79801 cacgactgct tccatgccca cgcagacggc ccccccacgg gaatcgaccg acgaaagtcc
    79861 gcaacctacc gccaaccccg agatcgacaa gactgcctgg gaggcgattc gctcgctgca
    79921 acgcccggga cgcccggata ttctcgcgaa ggtcctcaca acctatttga acgactcccg
    79981 gattctcgtg gaggaaatgc gtgctgccgt agaggctcgg gaccccggca ccctcgccaa
    80041 agccgcgcat cgactcaagt ccagcagcgc acagctcggc gtgttggcca cagcggccca
    80101 ctgcaaagag ctggaacacc tgggccgcct cgcttctctc aatgatgccg cgcatctgct
    80161 ggcccaactg gctgagacgc atcaagccgc ctgcaccagc atcgccgccg aacttcgaag
    80221 ccgctcctcc acatgaccgc ttagatcccg cgccctttcc cgtcacgcac attcctaggc
    80281 tgcccggcat tcacttccag ccatttcctc agtggaatcg tcaagttacc tgcaccctcg
    80341 accgataacg gagagataag tcctattcca tggagtcgca catgcgctgc cttgccagaa
    80401 cctacaactg gatgcttccc acaacgaccg gctgcctctt agcggccacg atcctgggga
    80461 ccccgctcac ctctttggcg gcctcgccga tcgaagacgc tcccttggtg caaacggagg
    80521 cctcgctgga tctccccgac ctaccctcct caggcacacc ggacggtcaa gagcccgtcg
    80581 ggaaggaaag tacgctcttc gaggagattc cctcagtcta tggcgcggcc aagtatgacc
    80641 agaaggtgaa tgaggcacca gcggccgtca tcatcatcac ggccgaccaa atcaagaagt
    80701 acggctacag aaactttgcg cagattctcg acagcgtgcc gggcctgttt accagcaacg
    80761 atcgaaacta tggctacctg ggaattcgcg gcttcaaccg gccgggcgac tatacctctc
    80821 gtgtcctgct gttgatcgac aatcaccggc tcaacgatgc ggtctacgac cagggcgggg
    80881 ccggcaccga aatgccgatc gacgtggatt tgatcgatcg ggtcgaaatc atcaaaggcc
    80941 ccggctcggc cttgtatggc accaacgcgt ttttcggcgt ggtcaatgtg atcacgaagc
    81001 ggggacgcga cctcaagggt gcggaggttt ccggagaagc cagcagcttc aatacgtatc
    81061 gaagccgcct cagttacggc aataagttct caaacggcct cgagatgctt ctgtccggct
    81121 ccttctcgga tagcgaaggg catcgccagt tgtcctaccc ggcattttct tcaatcaata
    81181 acgggattgc gaaagatgcg gaccgggaca atctgtacta ttacaccgga aaactctcat
    81241 acggagactt caccctcttg ggcggccacc agtggcgcaa aaagaacgtg ccgacggcct
    81301 ccttcggcac ggtattcaac gacaatcgac agaacacgct cgacgaacgg acctatctcg
    81361 atctcgtcta tcagcacgaa ttcgtcaacc agctcaatgt gaaagcgcgg gtctactacg
    81421 accgctatta ttatcgtgca caccttccgt acgactatgc cgggaccggc acaccgccgt
    81481 ttacgctcaa caaagactcc acagaggccg actggtgggg cgcagaactg acgatcacca
    81541 agaggctgtt cgaccatcat aaattcacca tcggctcaga gtatcgagac cagtttcgcc
    81601 tcaatcaggc caacgccgat attgcgccgc ccagcacgta cctcgacgac aaacgtcgat
    81661 cgagctttat tgcggcctat atgcaggatg aatgggccat caccgaccat ctcgtcttga
    81721 ccgccggtct ccgccacgat cagtacagta cgtttggtgg taccaccaac ccgcgtgccg
    81781 gcctcatttc gacgtgggat aagaccacgg tgaaattgtt gtacggccag gcctttcggg
    81841 cacccaatcc gtacgaacaa ttctacgtga cgggatccac gttcaaggcg aatgccgaca
    81901 tcaaacccga gcgcatcaaa acctatgaac tagtggtcga gcagtacctg ggggatcacc
    81961 tccgcgccct cggcagccta tatcaataca acatttccgg tttgatcagt cagaccacgg
    82021 atccgacaga cggaaagttg ttctatagca acgtcgacaa catcaccgct cgcggcgtgg
    82081 agttggcgat ggaagggaaa tggccctcag gcctcgaagg gcggttgagt tatgccctcc
    82141 agcgcaccga aaacgacgat ctcaaacaac agttgacgaa ctcgcctcag cacctggcga
    82201 aggccaacgt gattgtcccg gtgatagccg acaagctctt cgccggattc gaagggcgat
    82261 acaccagttc acgcctcacg ctcgccggaa acagcgccag tcccttttac attctgaaca
    82321 tgtcgctctt cagtcagcgg atcgtcaaag ggtgggagct gtccggacat atcaataacc
    82381 tcatgaatca gaaatatggg tatcccggct cgggtgagca cgtgcaggat gtcatcgatc
    82441 aggatggccg gacattctgg gtcaagctga agtaccgctt ttaaggaacc ggcatcaccg
    82501 atgcgtcgac ttatccacct catagcggca ctagggatcg cgctcaccct gagcgcgctc
    82561 tggctcattg cgagccccga ttcggcctgc gctgaatccg gccgtatcgt ggtgttgagc
    82621 gggcaggacc tcaaacccta tcaggacgta ctcgcaggac tgcaacaatc gctgaccaaa
    82681 caaggcatca atctggcggt ggaaatccat gcggcccaag gcgctccctc gaccgcgaac
    82741 gtgcttgaag acatcaagaa gaatggcgcc cggttggtgg tgacgctggg aagtgccgcg
    82801 acacaagccg ctgtgcgtga agtgggacag gtccccatcc ttgccaccat gatcgtcacg
    82861 gccgatgaca tcaagtctgc ctccaacgcc accgccgtct tactcgactt tcccctggat
    82921 ctccaaatgc agtggctgca tcggatcgtc cccgccgcca ataccgtcgg cgtgctcttt
    82981 aatcccaaag aaaaccagac caaggtgaac catgctctcc gcatcgccaa agaaaacggc
    83041 ctgagtcttg tgacacaagc ggtggacaca cctcgcgccc tccccgacgc attggagaac
    83101 ctctcgcgcc atgtcgatgc gctctggggc atctcggatt cggtcgtgat gacccctcaa
    83161 accgccgaac cgatcctgct gagcaccctt cggaacaagg taccgctcgc gggattgtcc
    83221 gcgtcatggg tcaaggcagg cgcactgtat gcgctcgatc gggactacct cgacatcgga
    83281 aaccaatgcg gagacatcgc cgggaaaatc ctcgggggga ccagtgcctc gtcccttgcg
    83341 ccgatatttc cgcgcaaagt gacctactcg gtgaatctga agacagcagg cgccatgaac
    83401 ctggaattgc cacaggatgt cgtgcgcggc gcgacgcata tttttcagta actgcggcga
    83461 ggatgacgat gataaaaaaa ggaatcggtc tacgggacaa gctcaatctc ctgagcatcg
    83521 ggctcgtcgt cctcacggca atcggcatcg cgaccttcgt cgtgcatcgg gaaatcacca
    83581 cccgctatca cgatctggtc aacaccggtc tcaccaccgc cgcgatgatc gcgcagaaca
    83641 gcgaatacgc cgtctatacg gaaaaccagg atgccgtgcg gcgggcggtc ggaggacttc
    83701 atgccttgcc ggatatcgcc tatgccgccg tgctcggcaa agagcggctg ccgatcctgg
    83761 aagaaacctg gggcgccaac atcgctatcc ccacggcgct gagaacacgt ctacttgccg
    83821 caggagacgc gctgttcgag gaggtggcca tccagcaagg gcatccggcg tatatcgata
    83881 tcctagtgcc cgtcgtgagt cggccggcag cggctgccga tccgctcttt ctggagtcca
    83941 atgcttcctc cccccctggc gcggtcatcg gctacattca gctgggcctc agtcaggaac
    84001 ggctgcgaaa gaatcttcag gaatttgttc tcatcacggg acttgtcatc ggagtcgtgt
    84061 tgctggttgg actctgcatg tcgttgatcc tgaccagaag catcacgaaa cccattctgg
    84121 cattagtgga agcggccgga cacatcgcgg aagggcgcct ggacgtggat gtcgctgcag
    84181 gcacccatga tgaggtggac cggctggcgg acgccttcaa ccggatgacc ggccggttgc
    84241 gaacctcaca gagtcaggtg caggaatacc agcagagctt ggaagacaaa gtgactcagc
    84301 gaacgaagca attggaactc gcgtcgcaag aagcccagcg actcgccgaa gaggcgcagg
    84361 cggccagccg cgccaaatca cagtttttag cgaatatgag ccatgagatc cggacgccga
    84421 tgaacggcgt tcttggcatg accgagctct tgctgtcgac cacgctcgac acccgtcagc
    84481 gccacctgac caagaccatt cagcaatccg gcgaagcgct tctggcgatc atcaacgaca
    84541 ttctcgactt ctccaaaatc gaagcaggca agcttcagct cgaacaattg gatttcgatg
    84601 tacaagacac ggtggaaaac gccgtggaac tgtttgcggg gcctgcccaa cggaaacaga
    84661 tcgaactgac ctgtcagctg atggggccct tcacacacgc gctccgcggc gaccccatcc
    84721 gccttcgcca ggcattactg aatctcatca gtaacgcctt gaagttcacg gccaaaggcg
    84781 agatcaatgt gcgcgtctat gcggtgacgg aaacgaacac gaccgtcacc cttcgattcg
    84841 aggtaaaaga ttccggtgtc ggcattccag ccgaggcgca tcagcgcatt ttcgaagcct
    84901 tttcccaggc cgacggcaca accaccagac gcttcggtgg cacgggactc ggcctcacga
    84961 tcgtcaaaga actcgtggcc ctcatgcaag ggcagatcgg cgtggagagt caagtgggcc
    85021 agggttccac attctggttt acggcggtct tcgagcgaca accggcagcg gctcccggac
    85081 aggaacaggc gcccgaacaa gccttatcca agaaacgcat cctggttgtt gacgacacgc
    85141 ccgctaatcg cgagatcctg tatgaacatc tccgcacgtg gggcgcgctt ccaaccttgg
    85201 ccgcttcggc acaagaagca ttggtactgc tcggaaccgg ctccaactcg ccacagccgt
    85261 tcgacctggc cattcttgat ctgcacatgc cggacatgga cggcctggag ttggccaagg
    85321 cgattcgcat ggatccacgc ctcgccggct tgccgctctt gatgctgaca tcggtggggt
    85381 atgacgccaa gacccccggt acgccggacc tggatgcctg ggtgactaag cctgtccgga
    85441 acaccctgct tcgccaagcc cttctcggcc tgcttcacac caggcatcgt gcaccagttc
    85501 agccgcccgc gccgctcccc tccgcgtccg gcccgattcc gttccaggcc gcccatctcc
    85561 tcctggtcga agacacaccc gtcaatcgag aggtcgccct cggcatgttg gacatgctgg
    85621 gccacttcgc ccaggccgtc gaaaacggac gcctcgcggt cgaagcggtc gcgcgggaac
    85681 ggttcgatct cgttctcatg gattgtcaga tgcccgaaat ggacggcttt actgccaccg
    85741 ccacgatacg acaacaggaa cgggacgccg cagaccaccg ccatgtgccc atcattgccc
    85801 tcaccgccaa tgccatggaa ggtgatcgcg cgcggtgcct ggctgccggg atggatgatt
    85861 atctggcgaa acccttcacc atggcacagc tgagtgagat gttgacgcga tggctgaccc
    85921 tacaggcgac tgctgcgccc atggccccag gcccttcccc atcggcccgc caggacgact
    85981 ccccgtctga tcagaccccg ccgtccgctc ctgtggagat tgacaggaca gcctgggacg
    86041 cgatccttgc gcttcaacga ccgggccgtc ccgatatcct agcaaaagtg ttgacggcct
    86101 atctgaacga ttcccgcacc ctcgtcgggg agattcgcac tgccgttcaa actcaagacg
    86161 ccgtcgccct tgccaaggca gcgcaccgat taaagtccag tagcgcgcaa ctgggcgcct
    86221 tggccacggc cgcccattgc aaagaactgg aaaacttggg acgcctcgcg cgtctggatg
    86281 atgctcctag tctgctggcc caactcaccg acgcccacca ggccgcctgc gccgcaatga
    86341 ccagtgagct cttgcaacgc ccagccgcct gattcgacac tcacggatcc gttcgcgact
    86401 tgcgaaccaa gccggtccgc gctagtctgg gcccacccat ggctacctat gcaatcggcg
    86461 acgttcaagg ctgcttcagc tccgtcacac ggctcacgaa gaccattcaa ttcgatccca
    86521 agcaggaccg gctctggttt gtcggcgatc tcgtcaaccg tggccccgac tcgctcaagg
    86581 ttctgcgtta catccgtgct ctcggccagg cggccatcac ggtgcttggc aatcacgata
    86641 tcttcctgct cgccgttgcc gccgggctga cgtctcctcg tcccagtgac accctatccg
    86701 cgattttgga ggcgccggac tgtcgtgaac tgatgctgtg gttacgccag caaccgctgc
    86761 tgtatcggga gggcgatttc ctgctggttc atgcgggact gctgcctgcc tggactgtcg
    86821 aacaggcaga gacattggcc agcgaggcgc acaacgcgat acggggagac cagtttctga
    86881 cgaccttgcg cgcgctccat cccagcggtt cgttgcaatg gcgccctgac ctcacaggcc
    86941 cggttcgggt agccaccatc atcaaagtgt tgactcgttt gagagcctgc tcggatgacg
    87001 gcatcatgga atcttctttc tctggaccac ccgatcagac cccggatggc ttttacccct
    87061 ggttcgatgt gcgcggccga cgtagcacag cggcaaccat cgtcttcggg cattgggccg
    87121 ccatgggctt gcggctcaca ccaaacatgt tggcactgga cagcggctgc gtgtacggca
    87181 gacagctcac ggcagtgcgt ctggaagacc ggaaagtgtt tcaagtcggg tgcgaggaga
    87241 ctcgtggcgg aaagtgatca gccggttcta gccctgtggc cgcggtatac cgaccgaccc
    87301 cttccagctt accgcttcat tcccggacga acgccacatc ctcgccgtca cccgcaaggc
    87361 cattcattcg aacagcccga tcctcttctg cgcccgttcg agccagaaca ttggaaaacg
    87421 tccgaagact atctgtacgg catcgatctt tataactgga cctactggtg ggaagcgcac
    87481 gaagtcttcg aagcgttctg gcatgcttac gggaggcata caccagccgg gaatttcttt
    87541 caggccctca ttcaatgcgc cgcggccaat ctcaaacggg aactggggca cgaacaggcg
    87601 acacgaaacc ttgtttcacg ggcgctcgct cgcctacaaa aatgtcccgt tcactatatg
    87661 ggcttggata cggaaatcat cgccgaacag ttcacacagt ggctgaatca gagggagcca
    87721 cacgggcacg ttctgtttgc gttatcgaaa gcaggcggga aaacacggaa cagttgaacg
    87781 ccagtgggag gctactcagt ggtagctttc cgagtcggac gggaacacac ctttctccac
    87841 atcctccttg tactgacgga gagcctggag cgcctcgacc ttgaggtggc cgtacggctt
    87901 tacaaacttc ggcacaaact cgtcaaacaa tcccaacaga tcgtagagca ccagcacttg
    87961 cccatcgcag tgcggccctg cgccgatccc gatggtggga atcgtgagcg cctcactcac
    88021 tgtctttgcc aatcccgctg gaatcgcttc gaggacaatg gcggccgcgc ccgcctcttc
    88081 cagcgcgcgc gcatcctcca gcagctgttg tgcgcgatct ttgccctttc cctgtaccct
    88141 gtagccgcca tattgctgga ctgactgagg cgtcatgccg agatgcccga tcaccggaat
    88201 gccgacgttc gccatcgccc tcacacgatc cgtcattgcc gcaccacctt ccagtttgac
    88261 cgcatgggct ccgacttgaa ggagtcgccc ggcatttcga accgcttctt cctggttgac
    88321 ctggtaggag agaaacggca tgtcgccgat gaccagtgag cgctggaccg ctcccgcgac
    88381 cagcttggta tggtagagca tctcgtccat ggtcacggaa agcgtgttcg ccttgccttg
    88441 cacgaccacg cccagcgaat cgccgactag aatgacgtcg atccctgcct gttcgacgat
    88501 acgggcgaag agggcatcgt aggccgtcac caccgcaatc ttgcgtccgt cgcgcttgca
    88561 cttctgcaag tccgggacag tcatcacccg agctcagctt tcgtcagaat ttccggcagt
    88621 cgttcggtgg atttgatggc cataatgtgg acgccatcgc agtagggacg gacggccttg
    88681 atcgttcgca cggcaatctc cacgcccgcg tcgagcgcgc gcttatcacc ggcggcacgc
    88741 atttcgtcga tcatgtcctg cggaacacag acgccgggga tattggcgtt catgaattcc
    88801 gccatcttgg cattgcgcag cagcagaatt cccgcgagca ccttcacctt gaacggacgc
    88861 ac
//
LOCUS       DAOQPD010000006        79668 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_96_length_79668_cov_24.209338, whole genome shotgun sequence.
ACCESSION   DAOQPD010000006 DAOQPD010000000
VERSION     DAOQPD010000006.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 79668)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 79668)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79668
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_96_length_79668_cov_24.209338"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(759..1379)
                     /locus_tag="PK063_02765"
     CDS             complement(759..1379)
                     /locus_tag="PK063_02765"
                     /inference="COORDINATES: protein motif:HMM:NF015325.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HMZ95989.1"
                     /translation="MVQMWRLLLLCATSILIGPTIGSSADSPPITQVLVAYHSLSGNT
                     ERMAAAVAEGARTVPHTEVIVRRIGSVTAEELFAADAIVLGSPVYWSNMAGEVKAFID
                     DWQFKFGVFPEFKLKNKVGAAFATGGQISSGKELTMLSILAAMLGNYMITVSGGGAFG
                     ASATTEGNSPGIDEQELGSARELGRRVADVAGAVKRGFALQERGVR"
     gene            complement(1512..1697)
                     /locus_tag="PK063_02770"
     CDS             complement(1512..1697)
                     /locus_tag="PK063_02770"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95990.1"
                     /translation="MKETRRVVYMRGVFVCPKCRQSYVQEKWIEEFRIRCHKCDYRGT
                     LTQVSVEEHMDEEVIRR"
     gene            1836..2345
                     /locus_tag="PK063_02775"
     CDS             1836..2345
                     /locus_tag="PK063_02775"
                     /inference="COORDINATES: protein motif:HMM:NF014678.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF192 domain-containing protein"
                     /protein_id="HMZ95991.1"
                     /translation="MTQSMDHSSQTPHSTWLSRLTSCLWSLAIVASPWSGWAADLPTE
                     TLIAVKMPNGTVIQAELADTALKRAQGLMFRERLADDRGMLFIFGDAQPWTFWMKNTK
                     IPLDIIWMDAKKTIVHIERNTPICTRQDDGCPQYHSEEGALYVLELGAGRAAALQLQR
                     GVKLSFKQP"
     gene            complement(2364..3881)
                     /locus_tag="PK063_02780"
     CDS             complement(2364..3881)
                     /locus_tag="PK063_02780"
                     /inference="COORDINATES: protein motif:HMM:NF013117.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HMZ95992.1"
                     /translation="MTLGSLAGSILAILACAAGVLGALTYVFTRRGKPVPVLPFYAGG
                     VGVFFVVASLIGHSGLGTSVPHFIQSCLNVAAWLGAAFFFFTILDVLIIGEWLIERGQ
                     RYIPDIVRQLLIGAEVVAAGVLILWLVMGINLVALVALPTVAAAMVGVALKDTLTRFF
                     SGIELGKIVKVGDWVTVLDREGVVTHIGMEHVTLLTRAHDVVSLPNDLVIQSGVTNFT
                     RPTTTHFCNVFVDAAYRTPPEQVCATLLETASSVSGVLPDPKPSAFVTAFNESAIQYR
                     IKFPIGDFSQRDSIESAMRTYIWHAFARTGIEIPFPQRVVHQSANGQDAAQDRYAIER
                     IMAKLTAVDFLATLDTKQIEVLAEGARGELYLPGERIVRQGDPGEVLYVIVSGTADVR
                     LEQGGLTTTVSTLEPGKFFGEMSLLTGEPRSATVVAVTQLSVIAVSKSALLQVVQEDR
                     RLIERIGEVVARRQAVTAAAKAQLSRDAAALSVVTHTRSLVERIQSFFWGTRKST"
     gene            complement(3930..6113)
                     /locus_tag="PK063_02785"
     CDS             complement(3930..6113)
                     /locus_tag="PK063_02785"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HMZ95993.1"
                     /translation="MPHETVTELDQLIERVKSYNVEADLDLVRRAYDFSAKAHEGQMR
                     RSGEPYFRHPLAVAGLLTHLKTDVTAIVAGLLHDTLEDTLATPLELEQRFGKDVVHLV
                     DGVTKIGKITFRNYEEKQAENFRKMVLSMADDIRVVLIKLADRLHNMRTLEYLSEGKR
                     RQIAQETLEIYAPLANRLGIGWIKNELEDLCLKHLKPDVYEMLRVRVAKRDEDRQQYI
                     HEVIDMVKKAMAEAGLYGEVSGRPKHLYGIYQKMEKQSISFEEVYDLAALRIITDIKM
                     NCYALLGVIHSLWRPLPGRFKDYIAIPKSNMYQSLHTTVAGPKGEHVEFQIRTEEMHR
                     VSEQGIAAHWKYKEHGRIDEKDGKVFSWLRQFVEWNQDLPDNRQFMDSVKLDLFHDVV
                     YVFTPQGMVKELPKGSTPVDFAYSVHTEIGDHCVGAKVNGKIVPLKHMMESGDMVEIL
                     TAANQTPHRDWLKFVRTSRAKTKIKHWIKAEEQSRSIEIGKRLLEAEFRRHGLAPAQM
                     MRSEQLLAVAKQVGYETAEELAAAVGFGHVPTSQVMSKIAPPLPGEAQTVAPEAPVPH
                     KPVIGRTDDTGVQVKGARDLLMQLSRCCNPVPGDRILGYITRGRGLTIHTIDCPNLEA
                     LDYDKNRLVEVEWDQSTPSTHSVKVSVIAVDKTGVLAHVSTAISECQANISRAEITTR
                     EDRKAMLDFIVEVADTAHLSRVFKAIEKVEGVITVRRMRSWQERA"
     gene            complement(6116..>7604)
                     /gene="recJ"
                     /locus_tag="PK063_02790"
     CDS             complement(6116..>7604)
                     /gene="recJ"
                     /locus_tag="PK063_02790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008297 - single-stranded DNA
                     exodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HMZ95994.1"
                     /translation="ALAREERVCFYGDYDVDGVSATSLYLSFYRGLGGNACGYIPHRV
                     REGYGLNEGAVRKLAQEGVTLLVTSDCGTTSHHEIAVAKELGMDVVVTDHHQTDATMP
                     AALAVLNPHRRDAIYPFKGLCSAGLAYKVVTAYQRRYGSGEVDPESCLDLVALATVAD
                     IVPLQDENRILVREGLIQINRGARCGIRALKQVAGITKACTSETIGFRLGPRLNAAGR
                     LDHAMLCVQLLTTESDREAQQIAEQLEQLNRQRQQIEEEITAQAGASLQQDEPAAAIV
                     LGSRHWHLGVVGIVAARLVDRFHRPSIVIAVDEKGLGKGSARTVEGFDLYQGLSACRD
                     LLEAFGGHPSAAGLTIQESRLEEFRRRFCEVAAQWATASLVRPTLHVDAEVKLTEVNF
                     DLIQELESLHPFGAGNPEPTLAVRGLDVVEARVVGEKHLKLRVRQGRSFIFDSIGFRM
                     GSFEELGLKTGRPVDLAFSPERNHWNGYDRVQLRIKALRMSGEVS"
     assembly_gap    7605..7704
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(7922..9976)
                     /locus_tag="PK063_02795"
     CDS             complement(7922..9976)
                     /locus_tag="PK063_02795"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009678 - pyrophosphate hydrolysis-driven
                     proton transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-translocating pyrophosphatase"
                     /protein_id="HMZ95995.1"
                     /translation="MSDSAIVTFALVAAVAGIAYGLYLAMWVFKLNAGNTKMQEISKA
                     IQEGAGAYMNRQYKTVGVVAAVLFVLLWGAGAVSDKFGMLTAVGFLIGAGASALAGYV
                     GMIIAVRANVRTAQAAHNGMNAALTVAFRGGAVTGLLLIGLGLLAITSFYTLASQLAG
                     QEKAIHALLSLGFGGSLISVFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVI
                     ADNVGDNVGDCAGMAADLFETYAVTTVAAMVLAFTMFKGVNAPILYPLALGGVTIFAT
                     IIGILFVKVSPGGEIMPALYKGLFVAGGIAAVAFFPITSQIMEGVGGVSGISYYLAAL
                     MGLAVTLALVFITDYYTSKAYAPVKDIAKASETGHATNIIAGLAVGMQSTAAPVVVIG
                     AAILASYWICGGAASGGLYGVAVAAVSMLSMAGIVVAIDAFGPITDNAGGIAEMAHLG
                     KEVRDITDPLDAVGNTTKAVTKGYAIGSAGLAAVVLFAEFAREVAKGTQASTFDLSNP
                     SVLVGLFLGGMLPFIFGALCMKAVGQAAGLVVEEVRRQFRTIKGIMEGTGKPEYGTCV
                     DIVTQAAIAKMMIPGLIPVVAPIIVGVILGPQALGGVLVGSIVTGLFVAISMTSGGGA
                     WDNAKKYIEEQGLKGTDTHKAAVTGDTVGDPYKDTAGPAINPMIKVINIVALLIVSLI
                     VK"
     gene            10317..10571
                     /locus_tag="PK063_02800"
     CDS             10317..10571
                     /locus_tag="PK063_02800"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ95996.1"
                     /translation="MGFAPEYILIDQQKFSKAKLSLDNHVYKNCEIDDCDVYYSGGQY
                     ELIDTHITNSRLILNHPAKGIYSAIQIFKMKSPGSSIISE"
     gene            complement(10669..11907)
                     /locus_tag="PK063_02805"
     CDS             complement(10669..11907)
                     /locus_tag="PK063_02805"
                     /inference="COORDINATES: protein motif:HMM:NF024827.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiheme c-type cytochrome"
                     /protein_id="HMZ95997.1"
                     /translation="MENRRGLLRGLIIMALLMVIGLASYGVQQGLAQDAKSQLTIEKS
                     FPSSGKCKRCHERVFEEWETSPLSKSIHTPTFRAALDAYLTSPAGKDKALCFRCHAPH
                     VREFPDHVQLFVTQAQSGEPSLDGVACAQCHLIKQVDRTKQPPEPKYDLGNKTMYGPY
                     KDFAANLAHQSMESALFHKSDLCLNCHQVVPVAADLGKSNDLLGNWDQSKAVKSGKEC
                     QTCHMPEQVGESANGEAKRKVANHTFPGRIGQLRQEAAKLDVATKVEGDKTSVTVAVQ
                     SLVPHNLPTTHPGWASVVLELTVKGKNLKTVFSDKRVYGRTYADAKGQKTVFDFEAVK
                     VLEETVLKPEETRVEAFSFPTPKDTKTFDVEAILSYAPVTGPASFLQRIEAESSKGAQ
                     DPVFQPIPIAKFSENVPVAK"
     gene            complement(11975..13285)
                     /locus_tag="PK063_02810"
     CDS             complement(11975..13285)
                     /locus_tag="PK063_02810"
                     /inference="COORDINATES: protein motif:HMM:NF024827.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiheme c-type cytochrome"
                     /protein_id="HMZ95998.1"
                     /translation="MIGTGRTIQKWAMSGLLMVFALLTVTFHERAIAQKTDGQAPADW
                     VAEIEKIFIRSEDCKQCHDRHYEEWKGMREQTPDLKSFGRVDAALLHGTSFESPVFRT
                     VLGVWMQTNPSLEERQRCLSCHAPAVTVFPQHAEKITAQVLSGKPQVEGIGCASCHLI
                     DAVETAPMPPPTYKVKPSEMLYGPYADPEENLVHPATQLPLFRGANFCTSCHFDKVKD
                     VTQKDLPGEILRGTICQDCHMEPSTGSSTSRRGAMTRSIGRHWFRGVVIPGTLLKNRN
                     LQAEWMPRIDIEATKAATGVEGTVLVKVGSLPHSFPDGDPVLKQFFLSITIKDAQGHI
                     LAEETKHFGLPYEKILRGPIPDPFIKGGNTRRVPFSQTLPAGGEEASTIEVVLNYALI
                     PEPEPELKAKYLATLPTDQERAAAKKVIEEYIQPRMLTYRTKSL"
     gene            complement(13301..13720)
                     /locus_tag="PK063_02815"
     CDS             complement(13301..13720)
                     /locus_tag="PK063_02815"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HMZ95999.1"
                     /translation="MCGAALLLAATVGNPSIAAGSGSNGEMTVEEAIQLGEEFGIAVG
                     EVDEEVQKELKLQRPEGVAVFEVIGNSRADYAGIKVRSVIKEIDKKEVRNLIDFGKAV
                     KVAMKECNFTVGTYEPADPGDPVGWGVNFHFVGCKRD"
     gene            complement(13864..14697)
                     /locus_tag="PK063_02820"
     CDS             complement(13864..14697)
                     /locus_tag="PK063_02820"
                     /inference="COORDINATES: protein motif:HMM:NF021010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ethylbenzene dehydrogenase-related protein"
                     /protein_id="HMZ96000.1"
                     /translation="MTSVHTSRTRLLSLLSVLLLLALILGGLGIPIVSSEGMIIRAQA
                     VSGDIPVAPEDPLWQKISPMTLPLSGQIITRPVWPEPTAHALTVRAVHNGTDIAFLLE
                     WQDNTKNDRLTPGTFRDGVALGLPLGDAPAFFCMGQLDHYINIWHWKADWQSDIDRRA
                     SRTTEKDKGGGSEPRRFEVIPRRASSVEDLIGGGFSTLTTKEKQGRVQGKATWKDGTW
                     RVVMRRPLSSEEQENEAKLIPGHIQAVSFAVWNGENKERNGQKAIAPWFQLALDPVTK
                     T"
     gene            complement(14785..16038)
                     /locus_tag="PK063_02825"
     CDS             complement(14785..16038)
                     /locus_tag="PK063_02825"
                     /inference="COORDINATES: protein motif:HMM:NF013595.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96001.1"
                     /translation="METDVQLAPGYIETFAGNGKARSTGDGKRAVKAGIPLPHHVALD
                     REEQWLYFAESGSDRVRRVNLTEGTVHNFAGIGETCYSGDEGPCGEAGLYLPLDVACD
                     SKNDLYVCDSGSNRIRKIDRETGIITTVVGTGEHGFNGDGPALEVNLTWPAAIAFDAD
                     DVMYIADTQAHRIRRFDPRTGRVETIAGSWTAEDEAREQPLVARNLVVLSGDAIGIDF
                     SDDNGWLMPVCSDGLNLSMYLDDGRPALEARLYDIVGIAVDNAGDVYVVDKGSNRVRK
                     IDRQTGLISTLAGVCRYGYDGDGKPAAKSMLHAPEAIVFDQHNHAYISDTGNHRVRKV
                     EAGTGMISTVAGNGDSGYDDKNMGGCGAARFVAKDAAGALKHGDGLLAIEAVVNSPVG
                     LTLDSQGYLYICERGENKIRRAKLW"
     gene            complement(16084..16380)
                     /gene="tatA"
                     /locus_tag="PK063_02830"
     CDS             complement(16084..16380)
                     /gene="tatA"
                     /locus_tag="PK063_02830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase TatA/TatE family
                     subunit"
                     /protein_id="HMZ96002.1"
                     /translation="MFGSLGFTELILILFIVLIIFGAGKLPQLGEGIGKAIKGFKKSV
                     HEADAIEAEAQAQAQQQAEPVQAQAIAAQPPAPMPTPVVEQQVAAAPPAARAQA"
     gene            complement(16405..17217)
                     /locus_tag="PK063_02835"
     CDS             complement(16405..17217)
                     /locus_tag="PK063_02835"
                     /inference="COORDINATES: protein motif:HMM:NF024816.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ96003.1"
                     /translation="MDEHTQTGGTEQGSAAVDPGDQPLNPDEEIAEIEKLLSTEPDDF
                     QARCRLGELYFSKGRLDDALTEVKKSIEMAEGLRTEMNRSLAMYYSNLGTIYATKGMI
                     DEAEAEFKRALEVHAYDVLALFNLGRVQADKRKYMESKNYYERLVEITPDDPMAWYNL
                     AGVYVELDNPQVSDYNTMDMAIQCYLRVLELDPKHLEASFKLMEIALNHRKTDLAIKV
                     MESAVEHSPDEPLAYYNLISVYDKCKMFEQAEQARQRLKERFAKKAKEGSAS"
     gene            complement(17250..18371)
                     /locus_tag="PK063_02840"
     CDS             complement(17250..18371)
                     /locus_tag="PK063_02840"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96004.1"
                     /translation="MSAIAAAVERPTGRVDDQGLLFEYTIKLVLFVGFFELVLYRLVS
                     RLGMHISKIAAQHEWIGTVFQLLTSIGFALLNVVAIFVFLALVVLLVNRARARGLTGF
                     NAVTIPSVALLLVLTVAFLIVQPAMLGSIAYNVVTIIALTALMLEYLSQQQEWSKRVM
                     GTVYYFGISGWLYYQIFSTTYGWMGVIAAPPFVYEANRIGEALMVLASILVFWAYGRG
                     VSFRTRNKQQRRRAIWFGAVSAVVFFGLLFMDYFLGLYNPVLAHSIRKAGEGISWIFQ
                     MGMGYTFYLPFAFYVAGLLCWSYTVIRLVTMGRLAGYGLALMFIAGYALLFSSLTLMV
                     ILGVMLLTLDRPKGTVTEQATVSRPPLVGTQESLVGGQI"
     gene            complement(18452..20233)
                     /locus_tag="PK063_02845"
     CDS             complement(18452..20233)
                     /locus_tag="PK063_02845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HMZ96005.1"
                     /translation="MKVSLLFPPTWHPSQPYLSLPSLTGFLTQAGVKNVSQRDLGIEL
                     LDKVLTQSFAHGLYQQLVEKQRGLERERTGETGPGSAEQLARIIESLDRFPYLFERIE
                     LAKETLRGEGFYDIEAYRNSLFLIDKWLEVLSSLYFPTRMTVVDNQFGDYSIYSSKDL
                     IKAIRDEAQNPYISLFREHVLPSILTDRPDLVGVSITATSQIIPGLTLCRLIKELAPE
                     LHVTVGGSIFTRLVDNLRRCPWLFDLVDDFVVFEGETALLELVNQMDGKRDFSKVPNL
                     IYRQNGKITVNQPFYSENINQLTAPNYDGFPLDLYLSPEPVLPVQFSRGCYYKDCAFC
                     ALTLDHQNFRQRDPGKTVDDLVWLKERYGAQSFFFTDECFALSPTKRLCQQMIDRQVN
                     VKWTCELRFEKNLSRELLTQMRDAGCLKIVFGLESFNQRVMDFMKKGIKQESVRRIVD
                     DCVDLGIAVHCYVIVGFPTEKEEEALETMNFVVGNTKLHESYGFSCQPCLFDLEKEAP
                     IMSDPGSYGIRRIMRPATEDLSLGFFYEVQEGMTPAQAEQLYQQVYEKISEVVCELPF
                     NYSMADGLLYIARAKSQALQIPQPTVS"
     gene            complement(20507..21460)
                     /locus_tag="PK063_02850"
     CDS             complement(20507..21460)
                     /locus_tag="PK063_02850"
                     /inference="COORDINATES: protein motif:HMM:NF021010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ethylbenzene dehydrogenase-related protein"
                     /protein_id="HMZ96006.1"
                     /translation="MRLVQTRNKRLVFGILFSALIVGIMLTIGQVPLAVSQPVTIPVK
                     AIKGAIPMDGANPIWEGVPGVIIPLSGQTITTPMHPNISVKSVFVKAVSNGKDLGLRL
                     DWSDQTKNDTAIGPQDFRDQVAIMFPVNTAGAPPFQCMGQSGGTVNIWRWNAEWQKDL
                     GKDSAGIWDVDDQYPGIFWDYYFEEPAGGVTYPDRIGRSLGPFNSGIWSGNIMSDPTL
                     RVSSVEDLNANGFSTLTTQAHQDVIGNGVWEPSGSLKGGGYTGPTWRVVVKRSLETGD
                     ANDTQFKAGASVPIAFAVWDGSNIERNGMKSLSTWFTLKLP"
     gene            complement(21560..22537)
                     /locus_tag="PK063_02855"
     CDS             complement(21560..22537)
                     /locus_tag="PK063_02855"
                     /inference="COORDINATES: protein motif:HMM:NF014651.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone TorD family protein"
                     /protein_id="HMZ96007.1"
                     /translation="MTSKQVVQPTSPSSTAIAPPKAVPIKDSPAVERALNRSKIYLLF
                     SWSLLYPEDEEFLDYLQCGEFVEDGRAALDGLRLALDGIGGDRAIQKIALMKKQFDQI
                     EKLVSAECVNWQIGDLQTEHRRVFTNVITLDCPPYETLFGNDHVFAQSHVMGDIAGFY
                     KAFGVELSKDVHERLDHLSVELEFMHFLTYKESYSRCHDGIDKTEIVVDAQKKFVKNH
                     IGRWVPLFCRMLAKKSDTGLFKLIADCMSEWMDFEVAFLGVTVQPYSEADYRPATFNA
                     PEGQTYECGAQDKGNELSMLLSEVGAESFMDQKTKEKDGEKSEGPVGTA"
     gene            complement(22747..23352)
                     /locus_tag="PK063_02860"
     CDS             complement(22747..23352)
                     /locus_tag="PK063_02860"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96008.1"
                     /translation="MAGDPKYGRRDFLKDSVVSVAKAAREFAIHKDAPREQPAAPVRT
                     DWLRPPGAVDESTFLERCTRCSDCIKACPPGAIVSDLSNGTPVIFANQVACELCEDFP
                     CIAACATDALLPVADVVEVRMGIATVSHRVCTAGQGCHACVSKCPVDALSMDFHALRL
                     DVEQARCVGCGMCEQICKTVNDRIAVKVVPARNLSAGSLNY"
     gene            complement(23365..24396)
                     /locus_tag="PK063_02865"
     CDS             complement(23365..24396)
                     /locus_tag="PK063_02865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96009.1"
                     /translation="MTTGVEVSKPSMEIRFQPALLQEVIDSFIEKTEREGDPTYYKEF
                     HELADPIYEKFTLDDREAEFKKLYQYLFGIWGFSDIIRDAFNEFPDLKARVGVVLVKG
                     VLKEDQEGVDVLRKWGSVEHDLAKQFEEKGLKGVGIKLIPRRFYDPALTRYCRHELMH
                     INDMLDPAFGYDPDTRVGQNPGEETLILHRYRILWNISVDSRLIAAGKEPMLQKEDRF
                     KEFRSWYRKIPPAQLKSVFEGLWQTSYFTHSELVEMATDTLRILDRAVDVEGGEIPET
                     QNKVMLMPGFPCPLCRFPTYTWVEDMETKLEPYILDFIRENHPGWDVEYGACDRCVEV
                     YKLRADGVM"
     gene            24593..25699
                     /locus_tag="PK063_02870"
     CDS             24593..25699
                     /locus_tag="PK063_02870"
                     /inference="COORDINATES: protein motif:HMM:NF012618.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WD40 repeat domain-containing protein"
                     /protein_id="HMZ96010.1"
                     /translation="MSNSTTTPPTIPSAAPAPTQGASAQAPAIDHLEYWKTGFRELKT
                     FRGHSHGVWTVAYAPDGQTIVSGGVDRYVRIWDIETGRLLRSLRGHTADIRALVFTPD
                     GRTLASGSEDRTIRLWNPKTGEPTKLLFTRYDHNVCSLSLSPDGLMLARGSHNKDIKI
                     WEVTTGTDLMTLLGKDQYDHHWSVCVAFSPDGVHLASGSDIGKIRIWEVLPSGEEKIL
                     HNGHWEETAEDSTETRGFFIEDDGGFQKPMEFWIGAMTFTPDAKILITGSRDNTIRFF
                     EMPTMNELRVLRGHNGWVRSLTVSPDGKVLISSGDDNTIRFWDIATGRNFRTDKTHTG
                     PVRGVALSPDGLRLASASWDRTVKLWEGGQEPAE"
     gene            complement(25701..27152)
                     /locus_tag="PK063_02875"
     CDS             complement(25701..27152)
                     /locus_tag="PK063_02875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ96011.1"
                     /translation="MKGLKIFIVDDEPLMRLSMQDALEGVGCEVMAAATGTEGVAVLG
                     TRQFDIVITDLRLPGADGLTILKTCKERSPTTEVILITAHGSVDTAVGAIKLGAYDYI
                     TKPFQMDELLLIVERVGKIIGLRRENLELKEVLEDRFSFGGIHGRNHQMRALLDKIKL
                     IAAADSPVSLVGERGTGKELVAHTIHLNSPRRDQPLIKMCCADLPDHLLEAELFGHEK
                     GAVPGASRQRRGRFELAHKGTLLLDDVDSLSPLLQSKLWRVLQERKFERVGGRESIEL
                     DVRILCASRQDLKEAVAQGRFRQDLCDHLAAVQVVVPPLRERREDVLVIAEHVLELRS
                     KSLNKSPKGFSQPSCDLLLHYSFPGNVGELEQMVERAVTLGRNGEPLQPWDLCGFQSC
                     PYLGGAPQATCGFCDEGLSAKADEPAAQAATTLATAREAFEKDYIETVLKQVDGSRTS
                     AAAVLGLSRKALWDKCKRYGISSAKGEAEERDE"
     gene            complement(27149..30325)
                     /locus_tag="PK063_02880"
     CDS             complement(27149..30325)
                     /locus_tag="PK063_02880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ96012.1"
                     /translation="MLFWSRSHSLQRKIITAIVMVGLLPLGLSLVLTYLEERRALRET
                     IGANFKEVAVEAARRIEMQVTRGINEAQQLAATPFLRTSVTESNRTYLDKDEKTVQSM
                     IKAWQQRWRQRDKQSEFPLFINRIVTNYLIRWHDIRKTDYVGIFVTDNRGALVVSSIP
                     QVEYYYGKTAWWQAFMKRGTGKVFVSDIFFDPAFGTHVVNVSAPIIDDEQHTTIGAVT
                     VLLRRDTLFHSVSEATIGQTGHAMLFSSDGAPMICPILSPEEHVVKPELVAAINSSAA
                     GWTTAENDSHGGKNSIVGFAPVRLGADLTPESLGGKRWVTFVRQDPAESYAPLSRLVV
                     QVTVYGLGVFAVLVLTGLTVARRIARPIGLLHEGVQKIGSGRLDQQLDLKTGDEIEQL
                     ADAFNKMAANLRVSFEQIEHRMEDVRRLEARYRDLIEHSPEMIYQLNKAGQFVHVNKT
                     GLDKLGYTLEEMLQMRLWDLVSKGREAEVLAYLERLVAQGRSTIETVFVAADGRPIDV
                     EIHSTALFEIGGGLVHSRAFVRDVTERRLLEEQIHRYTTRLEQAVNERTQQLVASQER
                     YKALFDLVADSVFMVGEDGVIVAVNKREEQALGYSEQQVVGHSILDVILPAHHEDMRS
                     LLAKIHSGERQVPTQEITVRDAGGKETPVEMDVILVRGSDHTWVMVQLRDITDRKRLE
                     RQMHTYQQELEAKVSERTREIEETKQYLENLLENANDVIYTLDSEQCFTYVNSKVLAW
                     GYAKEDLLGRPYLGLLSKRHRGRRLKSTLDIGVKQVYEVEVLTKSGEPRSVMVSVSPL
                     HGVDGEILGVLGIARDMTDTKKLEQQIRNSEKLASVGKLAAGVAHEINNPLGGILNCL
                     YNMRKGTLSPSRQEEYLASMEDGLRRVQRIVRQLLDFSQQHNPELALADINQVVNRVL
                     LLTDHLFVPHRVQLETDLAVDMPEIMIDRHMMEQVLMNLVLNAIQAMRNGGVLTIRTT
                     VKEAHCLVRVQDSGCGISSSVLPRIFDPFFTTKNEGEGTGLGLSVSLGIVERHGGRIV
                     VESEVGKGTTFTVSIPLSTERYAIGRFS"
     gene            complement(30401..31318)
                     /gene="secF"
                     /locus_tag="PK063_02885"
     CDS             complement(30401..31318)
                     /gene="secF"
                     /locus_tag="PK063_02885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031522 - cell envelope Sec protein
                     transport complex [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecF"
                     /protein_id="HMZ96013.1"
                     /translation="MFEILGKTNIDFMGKRTISFALSGILAFLGIIAVLQIARGAANL
                     GIDFAGGTAVQLKFDQSIRIDEARRALESNGLGSAELQEFTQDNKLLIRVKASTTIEE
                     KVAERVMAVFSKEFPGNKFVVDSSMEIGPTIGKKLQEDAMIAVLISFVGIVLYIAVRF
                     ELRFGVAAALATFHDVLAVLGVFYILDKEITLLVVTALLTLAGYSLTDTVVVFDRIRE
                     NLRTRRREDEETIINQAINQVLSRTIVTSLTVVIVLIPLVLAGAEVLHDFSLALLGGV
                     MFGTYSSIFVASPLLLLWPGSAGSLLKRR"
     gene            complement(31331..32980)
                     /gene="secD"
                     /locus_tag="PK063_02890"
     CDS             complement(31331..32980)
                     /gene="secD"
                     /locus_tag="PK063_02890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031522 - cell envelope Sec protein
                     transport complex [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecD"
                     /protein_id="HMZ96014.1"
                     /translation="MKKVGGRLLALVTMVVASIIFFLPSYQPLYKELPRWVREVLPDK
                     GITLGLDLQGGIHLVLEVEEDRAVEIAVERTAAGLQDLLVEKKIPAESVKRTGSSQIT
                     IGFQNAELKAQVQKLLDEFPTYVENEGAGSGNKVVWELREAEIKRIKDSAINQALETI
                     RNRIDQFGVAEPLIQRQGLKQVVVQLPGIKDAKLAKDLIKQTALLEFKLLDDDNQLKL
                     DLPGRIQKGKEREEAFLKQVEAKVPEGDQILFERIVEKESGQEWLAPYLVKKRVMLAG
                     DVLSDARVSIGQFNEPYVSVTFDAKGAREFDRITGENVKKRMAIVLDNTIYSAPVIQE
                     RISGGRAQITGTFSMEEANNLSIVLRAGALPAPLKIIQDLTVGPSLGQDSIEKGIKAT
                     LFAGLLVIVFMAIYYRLSGVIANFALMLNLICLIGSLAALNATLTLPGIAGIILTIGM
                     GVDSNVLIFERIREELRQGKAVRVAIDAGYDKALLTIVDSHVTTLITGFALFLFGTGP
                     IKGFAVTLCLGIAINLFTALVGTKVIFDLFNQRKKIEQLSI"
     gene            complement(33016..33336)
                     /gene="yajC"
                     /locus_tag="PK063_02895"
     CDS             complement(33016..33336)
                     /gene="yajC"
                     /locus_tag="PK063_02895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HMZ96015.1"
                     /translation="MWDSVAWAQGTSGNAGAGGGLLSLVPFVLIFVIFYFMLILPQQK
                     RQKQAKAMLETLKKGDKVVTASGIWGTITNLGKETVTLQIADTTKIKIQKEHIARLRG
                     EEED"
     gene            complement(33357..34514)
                     /gene="tgt"
                     /locus_tag="PK063_02900"
     CDS             complement(33357..34514)
                     /gene="tgt"
                     /locus_tag="PK063_02900"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - queuine tRNA-ribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HMZ96016.1"
                     /translation="MLSFRITHEEAGGRARVGVLTTGRSEVATPAFMPVGSLGNVRSV
                     DGEELLKMGYGLILNNAYHLYLRPGHKVVEELGGVHGFTAWPGAILTDSGGFQVFSLA
                     KFCKVTDEGVVFQSHIDGSSRFISPETSIEIQEALGADIIMAFDHVVALPSSLDQVRA
                     AAKRTSLWARRCVEAKRRTDQSLFGIVQGGLDQSLRVESARDLVSVGFDGYAVGGLSV
                     GEDKADMYAMLDVTVPELPSAKPRYLMGVGMPEDLVEGVARGIDMFDCVVPSRHGRTG
                     WLFTSFGRVVIKQARYARDEQPIDPACRCPVCTRYTRAYLHHLFGVKEMLGARLNTIH
                     NLWFFAKLMEEIRNAVRSGTFQEFRREFHRTYVVDRPGGEGRSDVDNTNMS"
     gene            complement(34527..36281)
                     /gene="argS"
                     /locus_tag="PK063_02905"
     CDS             complement(34527..36281)
                     /gene="argS"
                     /locus_tag="PK063_02905"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HMZ96017.1"
                     /translation="MAQGVVQDRVADALAGALRSAQQRGILKIEQMPTINLEAPKRPE
                     WGDVSCTVAMSLSASERRPPFEIAQIIADHIQDRDALFSRVDIARPGFLNLTLQPDLW
                     MEVLRHIETQRAEYGHSRLGQGRRVLVEYVSANPTGPLHVGHGRGAAVGQALVRLLRA
                     TGHEVVSEYYINDAGRQMKLLGVSVLARYLESCGQAVPFPEDGYQGEYIRAVAARVKA
                     EQGVTLLSLSSSEAEQRSKDFAYRELLALIRQDLETFGITFESWFSEASLLSSGAVEQ
                     VLSELRSRDLLFDQDGAQWFRSSAYGDEKDRVVRKQEGDYTYLASDIAYHRDKLRRGF
                     DLLVDVWGADHHGYIPRMQAVVQAYGYPKERLRVVLVQMVNLLRGGRKVEMSKRAGEF
                     ITLREVMDEVGADAAKFFFLMRDSSTHLDFDLELAKQQSQENPVYYVQYAHARISSLL
                     RVAASRGIECPLPSQADLKLLNDPDELAIIRKLSVFPVVLEASAVELEPHRMAYYLRE
                     LAGLVHPFYNKHRILPPMTDLDATPAAPTEPSASTSRVPEAVSPGLTGARLALMWSVQ
                     QVVRNGLTVLGVSSPEQM"
     gene            complement(36380..37327)
                     /locus_tag="PK063_02910"
     CDS             complement(36380..37327)
                     /locus_tag="PK063_02910"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013257.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 9 protein"
                     /protein_id="HMZ96018.1"
                     /translation="MLLARPVLRALRCQFPQHEIALIAANAVGSLLCHSAELDRAFSL
                     EENYLSQLFAGFERLSDSFRTWLGQCELVVGWLSDADGAVTNTLRLAGVQQIQLQTPF
                     SSALATTHQADRYWEAVGMEGQREDFTSSLMLPAELERQGQDVLQAYDWDGSSPLILV
                     HPGSGSHNKCMDAWRLAKVIEWLIEARMAPMLLEGPADCRAVAQVLSSLTVPVPVIRE
                     LSLSVAAGVMAQAKLYLGHDSGMTHLAAALAVPTIACFGPTHASRWSPQGRAVAVISG
                     MPCVCSDWSKVETCHDKVCLHIPVESLIEACRSQLLRLS"
     gene            complement(37396..38004)
                     /locus_tag="PK063_02915"
     CDS             complement(37396..38004)
                     /locus_tag="PK063_02915"
                     /EC_number="2.7.7.77"
                     /inference="COORDINATES: protein motif:HMM:NF024214.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0061603 - molybdenum cofactor
                     guanylyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HMZ96019.1"
                     /translation="MIDDISGVLVAGGRSRRMGQDKRFMKVGGASVFERTLSVLRVTF
                     AENIVVLAEPIEGLDVQRCPVVYDLIPNAGSLGGLYTGLMTASRSRVFALACDMPFLD
                     PEVIRFMLSQDESADVIVANLGGRFQPMHAVYSKRCVPFLQAMAQRNELKIQNLFHQN
                     ALRMKILTENHLQAFGPGFRSFQNINTPSELASAEASPSIHP"
     gene            complement(38105..39946)
                     /locus_tag="PK063_02920"
     CDS             complement(38105..39946)
                     /locus_tag="PK063_02920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="c-type cytochrome"
                     /protein_id="HMZ96020.1"
                     /translation="MGLILNLTNNLGEQVVRLTMSKLRMNVKASPIIGAALGALLLSA
                     SAVGIGQAADLPEGFAKGDLAPAPPADMIEAGKRVYFTKCVWCHGVDGAGDGPGADRL
                     WPRPRNFNQGTFKIRHTASGELPLFNYNEKTPDSGKNDLFDTVTHGLPGSAMPPWEGI
                     LTEEQRIQVLSFVTTQLVKDRKFTDKQSETQTILQLGTIKPAEATEDSIKKGAQLIVD
                     KKCIECHGVEGRGDGNAFNLKDDWGFSIQPANWHKCWNFRGSRQDPYNVRNIFRTFST
                     GVNGTPMPSFADSTSIEDRWNIANFVNSLCERDEEGKPLGIDPLTDKPKINFVIPSSP
                     VEGEISSDPENEMWKKQGRRYVAMGGQITHKPRNFVNRIDDIWVKSLYNDKSVVYLIQ
                     WDDRTKSIAEGKLPWAPTQVNVENFGVKEQAPKTGEEGSIAAAQNNYAVYNDGIAFQF
                     PIKWQEIPAPFKPRYLFGDAKFNADILKWEADGSLRSFKGTGWDQDFEERDDFEEKVK
                     LLKSEWKNGQWTVMISRPLKGSKDDYDEYTRFDIGKYIPMVFFAWDGHNGDAGRKMAV
                     SAFYYTILQPPIPQEVYIYPAVIAVGVVFLEGWMLTRRANKKKGKVL"
     gene            complement(39937..40974)
                     /locus_tag="PK063_02925"
     CDS             complement(39937..40974)
                     /locus_tag="PK063_02925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HMZ96021.1"
                     /translation="MKALMSVGALIGVLGLLMLIGMIFGVVPSNTVRLVEGYMPMQVL
                     SELAVFVAGFTGLSYLANSMGMAIPRFWQGVLFWTFVQTYLKFRIYPPIPFSVRAMYG
                     VVSFVAVFMWVSANEEDWKKFRQPILNVLDANTGFHKALRTLYLILLPILIGGFSFLT
                     MKPSVDEPIELRTVHPAPPASTKVHGKTYTLQTSQNPYRVNLEGKYDQAYSNKLIVEQ
                     GMGRLMAPNANPWDDKAEGYLKYVREGGEIFFQNCHFCHGDNLNGRGLHAFAFNPIPA
                     NFTDPGTIAQLQETFIFWRVAKGGIGLPNEGFPWASVMPPWEQHLTTDEIWKVILFEY
                     WHTGYYPRTWD"
     gene            complement(41027..42346)
                     /locus_tag="PK063_02930"
     CDS             complement(41027..42346)
                     /locus_tag="PK063_02930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase"
                     /protein_id="HMZ96022.1"
                     /translation="MIELIKSALSMGWPALGLLIGLMFYFKASISDPVANKRAVFKTF
                     IGIWGALLLFMAIANYKMNFFGESRLLPVSLVLITSMTFMMALYFTNISALLKIGGFM
                     FFIAAALSGYGNWLPQVEGGFPPIEEKKDFSNMPQTELADEGEKIIFGGVGQNKVQGA
                     IGKGQCPLCHAFHKGMLGERAPNLDGIPERAETQINDPRYHKGNPAARDSNQKEAFAG
                     SGTAENGIQYIAESHACPSCFVVAGFGVKGTNDKESPMPSIHKPPISLSLPELAAVDT
                     WLYVREGREAPGFDEIVKSYEKFIPESDRPKPPTEGDKAAGGGGASLMADGTEPVDQI
                     FAKGQCVACHTIPGIAGATGTIGPKLVEGTNAPLRIKDKDYKGKAKSVPDYIMESIVE
                     PSAYVVKGFPDNTMPKVFGQKLSAGALKKLVDYLSQIQEGKEPPKAS"
     gene            complement(42432..44348)
                     /locus_tag="PK063_02935"
     CDS             complement(42432..44348)
                     /locus_tag="PK063_02935"
                     /EC_number="1.10.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0070069 - cytochrome complex [Evidence
                     IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_process: GO:0019646 - aerobic electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="HMZ96023.1"
                     /translation="MGSVTRTKLMSVMALCAMIGLLLMPILVAIPALADGGAPAADAK
                     KEGGEAKVEKGKDVYYKTEGIVSGPPAPKTTDSEKDYPRYNFESRVLLWFANQQHLYY
                     GSFVLAVPIFCMVIEFMGVVTKDKALAKRYDQLAYDFIKISLTAYSLTAILGGILIFT
                     FLTLYPAFFQYLSGIFRPVMHIYALMFVAESGTLYIYYYGWDKMKEGFLKWIHLSMSV
                     VLNVIGTILMFLANSWIGFMMSPAGVDEQGRYLGNIWHVIHTALWNPLNLHRILGNMA
                     FGGGVVAAYAAYRFLSAKTDEERAHYDWMGYIAMALGVAFLIPLPFAGYWLMREVYAY
                     RQQMGITLMGGLLAWLFIIQATMIGILFLSTNYYLWQALGRMRGAEKYQRYIKYLVFL
                     LTCGYLVFITPHTIVMTPAELKAMGGQQHPVLGNYGVMSAKNGGINVIITTTVLSFVW
                     YMRGNKVSTVSWAKFGNIFMGCFFFFAYLNIIMLAVYGYYIPANVRVGLSVPQVATTL
                     SCLFFMFALNSVMMKGAKQMGPIEWGKISARSQYALIMLATAFTWMMGLMGYIRSSVR
                     LFWHVNEIMRDNSPWAYTHTVGFAANMISANVLFFWISIMFVFWLGALAAKKAPVEAK
                     AAVPGRAAAPAVGH"
     gene            complement(44412..44534)
                     /locus_tag="PK063_02940"
     CDS             complement(44412..44534)
                     /locus_tag="PK063_02940"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96024.1"
                     /translation="MGQTIVYFVVSILICVSFFAAVDHFLMDAQGLDFWYLLRK"
     gene            complement(44860..45813)
                     /locus_tag="PK063_02945"
     CDS             complement(44860..45813)
                     /locus_tag="PK063_02945"
                     /inference="COORDINATES: protein motif:HMM:NF015722.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
                     /protein_id="HMZ96025.1"
                     /translation="MLETRFKVVFLLAVLFAASLPIIAILRGTISTPLESEVQHSEED
                     SQSSASDSSIPDQPLEEELVRIPAGPFIRGTSQGGFDEQPERKIYLDEFFIDRYEVTN
                     AQYAAFVKATGHRKSGPPSRYAKNTGRMKGVNQPAVYVSWEDAKAYCEWRGRRLPTEA
                     EWEKAMRGTDGRLWPWGNVEMPGGANWGRINDGFEVTAPVGRVRSDASPYGVMDGAGN
                     VMEWVEDWYLEGAYAAAAERNPESPEYGTYKVLRGAGYTSSGSDLRITARSKMMADFR
                     DETIGFRCAQSKAGNAPLSGGVNDGKIIENQSSRGSETRPK"
     gene            complement(45825..46739)
                     /locus_tag="PK063_02950"
     CDS             complement(45825..46739)
                     /locus_tag="PK063_02950"
                     /inference="COORDINATES: protein motif:HMM:NF015722.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HMZ96026.1"
                     /translation="MENRGVLIGSIIFVFGSFILMIGGLVYESYKAKQMRQLALSIAT
                     EAKPVAAPLAQDFSMYKTFIGDDGREMVQISEGPFVMGSRDNDSDPDEKPEHQVYLKT
                     YFLDKHEVTQDSYDRFLKMTRRVKRKIEVFEDDPAKLLKPEYPAIAVTWDDAEAYCKW
                     AGKRLPTEAEWEKAARGEGKRRYAWGEEFISGYANIDGAEDGFRYLAPPGSFESGRSP
                     YGIYDMTGNVGEWVADAYDENFYRASPYRDPKGPDQGEQRIIRGGSWRETKRNVRASK
                     RFQAKPWRHDITVGFRCAKDVDADTAVK"
     gene            complement(46755..47144)
                     /locus_tag="PK063_02955"
     CDS             complement(46755..47144)
                     /locus_tag="PK063_02955"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96027.1"
                     /translation="MDRPTANTWFDVVLGIVVMATVGALIGSFLGASSIPVTAGLGLA
                     LGAVVGYLGGRRFLVSILVGTVLGGLLAWLIAGVEKVSFGAGAGAAMGGFLGVQISML
                     LDVRAARKAAQLEESEADATHSAVTKL"
     gene            complement(47177..47833)
                     /locus_tag="PK063_02960"
     CDS             complement(47177..47833)
                     /locus_tag="PK063_02960"
                     /inference="COORDINATES: protein motif:HMM:NF022694.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3047 domain-containing protein"
                     /protein_id="HMZ96028.1"
                     /translation="MRKLVGALGLLSGIALCSILGGAAPASAAETGVMVLEDFQSADQ
                     DGFPVDWQHENQRSQAKGRDAYKLQSEEGKKFLAAKDAGQRIKKRKIDWDPKVYPVLT
                     WRWRLHKAPSNSEPVAALYASLDTDLMFIPVFTKYIWSAGKPVGTFVEGGMFSGSELV
                     VQSGVVPVGEWVEERVNVYEDFKRIHKHEPADKAWGISLFAGPGVEIDFGAVTVGPAK
                     "
     gene            complement(47865..49733)
                     /locus_tag="PK063_02965"
     CDS             complement(47865..49733)
                     /locus_tag="PK063_02965"
                     /EC_number="1.10.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0070069 - cytochrome complex [Evidence
                     IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_process: GO:0019646 - aerobic electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="HMZ96029.1"
                     /translation="MTTRRSLSFVILLLVGGLLSVASLIVLSPPSIMAADPSNDVYFH
                     TPGTPSGPSAPTANDNHYPQVGSMDSRLLMWFIIQQHTYFGGFVLALPVFCVLLEFLG
                     LVARNPAMALRYDGLAQDLLKVALLALSVTAAVGSLMLTMFITLYPSFMQYMGGTFKG
                     MMPLYALVFVGTTFLTIAYYYSWERMAAPGTKWVHLSIGLLAVVCGTSLLLLANSWSA
                     FMMAPSGVDGQGRYLGNPWHLLRSALWNPLNLHRFLADIMSGGAVVLAYACYRFFSGK
                     SQEERAYYDWVGYVFLFVTVCALLPMPFAGYWLMRSVYAYSQSMGVTMMGGLLTWLFV
                     VQALLIGALFLGVNYYLWQSMGRIRGGERYQPYYQYLLLALTGCLFIWLTPHTLLMTG
                     TEVKAMGGAQHPVIGNYGVMSSKNGAVNVMICITALSYIYYRRANRTMTISWARVGNV
                     ILGALFGLGVAHIIGLSIYGFYLPASLRVGLSGPQAVTTLLVVTLGLLLNRRMLQGAT
                     IHGPVQWGQISVRGMVGLFGLAAAFTWVMGLMGYIRSSGRLAWHVNELMPDTSPWAFT
                     PTLGFAAKMVTINMVLFWGAVFFLFWVCQRGQQPVMHEDVSAEKEAGFLPSPSHEG"
     gene            complement(49730..50815)
                     /locus_tag="PK063_02970"
     CDS             complement(49730..50815)
                     /locus_tag="PK063_02970"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96030.1"
                     /translation="MLHRLALRVLPSLTLAVTEDSVRKRKRLVMFVPGLAAFAVYRAA
                     KQGFSLADPLTLLVLCGLVSMATALCAYRVGRGVPFRQLVTADGWQRIGWVLGWIGFV
                     YGIQLSLLVLALLWLVGYDYAKHPDGPAMMALIIPSTAVARDAFEIGYVRWLEACGRP
                     FITFPDGVALRNLLQRFDQALLTWVTAGVLGGVVLSALAAMAVSGDFAVLAQGGLVTL
                     AAGTVGLLAYFAGQGDQATLTSRLAATSWGELMKFWWWPGLAFAATYYLVLVGGCLYV
                     LKQPMNSIVLFAGVAALVGGVMPLYCYYLGYRREIESRQPGGVPSALLRCPFVMGILG
                     KSREAIVGSALSESAAVFEKSSQRVSS"
     gene            complement(50897..51391)
                     /locus_tag="PK063_02975"
     CDS             complement(50897..51391)
                     /locus_tag="PK063_02975"
                     /inference="COORDINATES: protein motif:HMM:NF019968.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PCP reductase family protein"
                     /protein_id="HMZ96031.1"
                     /translation="MLVCGCGGWMHTEGIEERRSHGGDATWFVRTECRPCRWLVGIDM
                     PAGQVDGLVDRLMWSDDAKHRLDRVPPYAAPALRELVEGFARSRRHRVITYELIDQAL
                     TGDVVAWDADAEQRLANVPAPVRAMARIELERTAVDRGERSVSVALMEEVKARYFGMA
                     AQRA"
     gene            complement(51424..52140)
                     /locus_tag="PK063_02980"
     CDS             complement(51424..52140)
                     /locus_tag="PK063_02980"
                     /inference="COORDINATES: protein motif:HMM:NF016153.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF420 domain-containing protein"
                     /protein_id="HMZ96032.1"
                     /translation="MFEFLRQPGFFGTHATMGADLSQLMATLFTGLFIIGWIQAKQHR
                     GHPHHWLMLGGMITMVGFFTAYYLFRQLGVLAFEGKEGFGGSQALYDYVFIPVLTIHI
                     ILVIIGLVMAVYMIVLGFRSQQFIGGSRVLSPSLLQTSWKKVGLIFGVLLTVVIVLFG
                     TRVMSAGFSMRKLEVYLGFLSLVAIVFAVEMGIQRIWPDGGQRHRALGRFTMIVYCIL
                     FLTGTFTYAMLYILYPGKIG"
     gene            complement(52143..53138)
                     /locus_tag="PK063_02985"
     CDS             complement(52143..53138)
                     /locus_tag="PK063_02985"
                     /inference="COORDINATES: protein motif:HMM:NF013087.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HMZ96033.1"
                     /translation="MPRELSLAEVFQLGYYWETKILLTAVKLDVFSLLDGQGRSAAEV
                     AQKLGADSRALELLLNALVAIRLLTKTGAVYANTSVATTHLVKHGPQYIGHLLLLHDA
                     EWGNWGKLEEAIKTGRSPVTQHVFETDPALGANVLSVLHRIGQQSGPDLAKRLALGQA
                     KTMLDLGGGAGTNAIAFCQVYPSLSATVFDLATTLPVTERTIKDAGLEGRIALKAGDF
                     NRDALGGPYDVVLMSDILHYQDLAINAALVKKIHSHLNPGGRLIIKDRFLDASGTSPA
                     WTAAFAVHILVNTEQGACYRTAEAMQWMHDGGYVSVEEIERTAVVQGVKPSAGQS"
     gene            complement(53415..54212)
                     /locus_tag="PK063_02990"
     CDS             complement(53415..54212)
                     /locus_tag="PK063_02990"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase-like regulatory
                     domain-containing protein"
                     /protein_id="HMZ96034.1"
                     /translation="MKKGAMKAVFGVAAAAFLAAPLTAFAGGTIAGKVTYPGKAEQKE
                     FSFAKFPNPKFCPKNPNKSLMDGDKRFLKTIEVAKDGGLKGAVVAVVDIEDQAFQDGF
                     KGTDVVAEFCEFLPFSGVVVNNKNFRAENKDADPDDPKSVQGVLHNPHSFTVKGSTSA
                     TGFNIGLAKKGDKLEKPVTFRGGAEKAGYYRLQCDQHEFMQSFFLPVWNPYHAVVKDD
                     GSFEIPGVPAGKHKVVVWHPFVGKGKLNEFEIEVAEGGTANLKAEIK"
     gene            complement(54415..55812)
                     /locus_tag="PK063_02995"
     CDS             complement(54415..55812)
                     /locus_tag="PK063_02995"
                     /inference="COORDINATES: protein motif:HMM:NF025030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HMZ96035.1"
                     /translation="MGLQTKRRWIRTVNLCLAAVIVSGPLVGLWPVPANAGSLKDAQA
                     AFDKKQYQEALDIIEQVTKEKGSQPETRRLKVRSLIFLGKPKDALVEYERHEQESKQE
                     DRPLLKDVSLGFIYALVKDMREQMRGAAYTALKDVDSAETIPALEDGLSDGSGLVRAL
                     AAEALGKLDAGRKSPRLRNALEDQAGLVKATVIKVLGKSGDRSVIPLLEKALKDEQPA
                     VRLAAAGALYHTGQTAMWETIQKAAAAPNPEERATALRMVGDLKDARGLSILLEAMTN
                     TQPSVRGAAASALGELGKVQGIPALEKALDDKIPAVKTSAAISLGELGVKESLVALRK
                     SLADPNPVVKAAVVSALLRVEEPFESVAEALYELAQNNDPGTRSAAGKAAGRAHGANT
                     QPAIEFLAGLLKDSIPRPRIAAARALGQIGGAEVLPILKAALHDEDDAVRATVGGSIA
                     RIIGHAKFPSNQAKS"
     gene            complement(55843..56334)
                     /locus_tag="PK063_03000"
     CDS             complement(55843..56334)
                     /locus_tag="PK063_03000"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96036.1"
                     /translation="MEGRRFEAQVFAKSDRIRLEYKYAIKTELGYSSIEILRLDKRES
                     WFLLAQRRQILSLPIKPEEILPIQPTLPGEQRRTLIGDATTIGRASRLYEVRVDYNGR
                     NERFYEWVDVETGIVLKLVSQDRDWSIEYLRFRLSPQPDYYFEEPTGYQRWVPKPNAQ
                     ERG"
     gene            complement(56489..57421)
                     /locus_tag="PK063_03005"
     CDS             complement(56489..57421)
                     /locus_tag="PK063_03005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase-like regulatory
                     domain-containing protein"
                     /protein_id="HMZ96037.1"
                     /translation="MMLNRTQRIHSFAAAVLVWLGVAVSPVGAYEVIDVQHGGTVDGT
                     VTLSGGIPDPKAFNLITFPDPTYCGRISNGSGWRLLRDFIVSPEGGLKNAIVTLEGVE
                     SGKAFDMSVPLIEARDCMFQPWVTIVRNGHAVEVVNMDPVMHDIQGYETSPEAGARVL
                     FNTPLILNHQHQRGNMRAVHNHAPGKSLVGPVYLNKGRRTFYMQCGFHAYMESWAMAV
                     NNPYYAVTDDQGAFKIENVPPGIYQMVVWHPQSGPGVTRTITIAPDGTTTEKVALPAP
                     KGVRTAYRAMENPRFGLESLGHPVEIQPLVEHQH"
     gene            complement(57449..58357)
                     /locus_tag="PK063_03010"
     CDS             complement(57449..58357)
                     /locus_tag="PK063_03010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase regulatory-like
                     domain-containing protein"
                     /protein_id="HMZ96038.1"
                     /translation="MRTAGIALLAALSSFSSQSWAYEEITVTDGGNITGTVTMIGGKP
                     TPKGYNLITFPDPVYCGRISTGTGWRILDEFSMTSGSGLKDVVVLLTDATKGKPFKFE
                     PLTIEARDCRFLPFVTVVKDGSEVTVMNMDPVMHDIQAYETSQLGPRVLFNTPLPMNP
                     HHKRFVTAESHEHLAGEPVKEAIHMTKGRRIFVMQCGFHAYMESWGLAVDNPYYALTT
                     DGGTFTLGDVPPGEYTLMAWHPALGTMLQKKVTVTEKGTSTVDFAFEAPKGRRSVHEI
                     EHNPHYGPESLGKVVDIRPTLERQVP"
     gene            complement(58511..63376)
                     /locus_tag="PK063_03015"
     CDS             complement(58511..63376)
                     /locus_tag="PK063_03015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multicopper oxidase domain-containing protein"
                     /protein_id="HMZ96039.1"
                     /translation="MDCQWFTRVTSRALSVIAGGALVCLPLAASAESQLHADHAVPQQ
                     TAMSHQLPSWAEKLKGQTIVEDAMAGKPERSAMVEQQHQRVMEHLTNDPQAQAVNTGM
                     FNTQTMMHQYGAGGQDLLLMSDPRVEPVAMTNGGKCPATAPVRQYNVSAINVEITLNQ
                     WLDFYPGYMYTLDENLDKVRAEETKNREARDKEGFDPGAVIPGVQAQWIQPLTIRGNQ
                     GDCVKIKLTNKLEGGEDVSLHIHGSSMVVSATGAAAATTNSDSIVQKDKSGEFEWYIH
                     PSTQEGVRQFHTFANDRELTVMGLFGSFVVEPRGSEYLEALGTGDATPTASGWQVIIR
                     NGTGPDFREFVLYYHEVGDEAFRPVNKKGDFLPQRDPLTDAYRPGGRAINYRSEPFGI
                     NNMHVQHEYFGFEDESMGYSSYTFGDPSPTIPRSYMGDPAKFRLVHGGSEVFHSHHPH
                     GGTIRWPRSPRAIDDMNLWTTAGNGPVKYPVIRAKTDRVDVEVIGPSEALDLETECGS
                     GLCQQLAGDFLFHCHVAHHYVAGMWGYWRVYNTLQQGDMRNDVMPDLRELPDRKGRIR
                     GPITSDKLVGQTVDWFGKSFKIVEKGKSDWKSNPAVVTIKDWVEMQLPTMGKPGHKND
                     EKGQTVSYDATVLDWAWEGTRALSEPESTIDNPKYKSTHPGKRHPITFEPLTGKVAWP
                     HLTPHFGRRVMFSPNHVGAPWLEMIRRDANGEESVDQALPGENGNWSLCPENAGRKHY
                     NVHFIKLPITIAKKTGKEPPVIDPNGLIYVLHEEEAEIRKNDDLKYPLVVRGNIYDCV
                     DWTLTSEWDDDDYTNFQSSKINTHWHFLQFDNQASDGVITGFSYEQSVRPFTMLEKKN
                     AKGLPVPMNTVVTAAAKKGANTITVKNAKQFHVGTLLLVGADNVKGNEISRIKAINGN
                     TITLAKGLKNDHPANDIVTVEFVRQRFWVDADVGTVFWHDHAFGATTWPHGGFGTFIA
                     EPVGSTYHDPKTGKLIRSGPIADIHTNEPVGHGVNNSFRELMVQVHDTVPHTVNVVTA
                     GNPPGQPIEVALEAGKTVSFMMPEKIYMTPMPFLNGGTHTTGSGLNFRAAPIAQRLAT
                     NPDASQIFSSQVHGDPYTPTLRAYVGDTMVFRLLHTLMNESMVWTLSGHTFWTERYAA
                     DANRKNSIHIGIAERYDLVVPEAGGSRHQAGDYLHFNGRSSKFSEGGWGIIRVLDKEQ
                     ADLKKLPAGFSIKGDIPKTLPVCPADAPVKQFNVVAMDYAGMKFNAKAPESIEVDFER
                     RILMTNAEAKIYALEEDTAKVAAGAHPMPLTLRVNSGDCVKVHLKNKMKDSKASFSAI
                     GLAFDPKDSMGANVGNNPGDQTVAPGGERDYTYYADPFNGETTSLVWDWGNVMTNPRN
                     GLFGAVVVGPKGSKYRDPKTGADLSNKNAWAADVIIDHSVPGNELRANYRDVALFFQD
                     EDNIIGTSFMPYVQNVAGLTGVNYRSEPYKFREEQGCSLGKVFQPCKADKPEDPATPL
                     IEAHAGDPVRIHVLGVSNEQNGMFSVEKHEWPIEPFMRGADLISVVEFSGSETIDAFL
                     PSAGGMYRMPGDYVYSNQRLPYSQSGQWGYVRVLPAGDTRLLPLTGAGAGAKSAEVEQ
                     PAAHAMPVASK"
     gene            63739..65553
                     /locus_tag="PK063_03020"
     CDS             63739..65553
                     /locus_tag="PK063_03020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HMZ96040.1"
                     /translation="MILKRWLVGLPLKTKEAAHERLSKRLALAVFSSDALSSVAYATE
                     EILLVLTLAGTAMVGYSIPLSLSIIGLLVILTMSYRQIIFEYPEGGGAYIVGKSNLGE
                     WPGLVAAGALMIDYVLTVAVSVAAGIAALTSAFPDLLAHREALCVAAILLVTVVNLRG
                     VRESGQFFAVPTYIFIGTLTAMLGVGAIQILLGHATRIEPLPSLTPAEPLTLFLLLRA
                     FSSGCTALTGVEVISNGVSAFKKPEAKNAAFTMIGMAVILGTLFIGISAMAYYFGIVP
                     KSDETVVSQIARATFGTGLLYFLVQASTMTILILAANSSFNGFPRLASILARDSYMPH
                     QMSMMGDRLVFSNGVIILGVFSCLLIILFNGDTHALIPLYAVGVFLSFTISQAGMVKR
                     WLVKKGPHWEKKLLVNGIGAVTTAIATVIIASTKFAHGAWIVIVLIPMLIMFFKAIRS
                     HYKAVSEQVALSRGHRPPLPRRNIVVLPIGGVNRAVIRAVDYARSRSGDIRAVLVDVD
                     PEETARVEIQWAQWGCGVPLTVLPSPYRSVLSSLLDYLEQVLQKDQECWVTVVIPEIL
                     PARWWQNILHNQRAFMLKGALLFKDRVILTDVPYHLTR"
     gene            65556..66677
                     /locus_tag="PK063_03025"
     CDS             65556..66677
                     /locus_tag="PK063_03025"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96041.1"
                     /translation="MRNPRATIHRTNRRVGAHLVAMVLLLGLSPHPGLAFTIVAPKNG
                     TTLTSGEPTTAEVEAGREAGLVEVRYYWYPEQTESLVEQGDERSGKGSQGSISTEKYW
                     QKDSITGAPVVALPALTSTVDRVPPYGGALPVPPDAVGRMRLLAIADISQGRLGRKTV
                     FDEVFVTVQPKAELLSIDFETEKPLQLGRTGQSSAYGHVDSLGKIFELPVVGEFADGI
                     SRPLSSPSAGTVYTSGNDQILKVLPDGLLQIVGIGKTSLTVTNRGKQATLDVRVEVNP
                     EPNEPPVANAGTAKTVKAGTKVRLSGLQSRDPEGEALFYAWAQVRGSKVAMLDVNMAE
                     PSFTAPYVSETRTFRFKLRVTDKKGADSVPAYVDVTVEP"
     gene            66988..67518
                     /locus_tag="PK063_03030"
     CDS             66988..67518
                     /locus_tag="PK063_03030"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96042.1"
                     /translation="MALIQQDLVAGSEDRLLTLDTETNLQWLNLSQTAGRSYQEIMNG
                     FGQFTTAHGFHYADGRQIGELCGHAGITKGLTEPALTPSPNDARNHQAIQTLQNLMDG
                     KVFHAETNVITSRGIMKPPAPPPNVPTRILGTIRLSLSLLNITGSHAESEGPTASPQT
                     GDPEIGSYLVRNQPEA"
     gene            complement(67656..69203)
                     /locus_tag="PK063_03035"
     CDS             complement(67656..69203)
                     /locus_tag="PK063_03035"
                     /inference="COORDINATES: protein motif:HMM:TIGR04267.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEXXH motif-containing putative peptide
                     modification protein"
                     /protein_id="HMZ96043.1"
                     /translation="MTVLDARMLERLMEEFRRSMQGLLTEVCRDFTKNYADAVSTFQL
                     PIDWFLSLGRSFPPAEFSNWKVVGWIESLNDLLYFVDIVTQVRQERSRRDIAEQLRAE
                     FREKFYEHGYTDEIFPNGKPEPRLLLGRLTALCHRLAREITQESVCLAPRLACAWVAK
                     QRRDAWLLPCDLTANVERVELPWGCAIGTTGVFYEATGAVRSALQRAKGQGEFLITAS
                     GIELLVGDRAYPLMTCGSQERWHWRRLDPLPLRDSRYGSLVLGPTLVYGKDKTPIGVR
                     PTKQEVAVRMRRALSAIAAAWPEGDRLLALLTSRIVPLKAAGVVSFSYRHRPGFSAIN
                     CFERDQLDLIDDLIHENSHHHLNLLLRNDVMYQHDHNQEVFYSPWRRTLRPLRGILHA
                     TFTFTMGAMLFERLVVWGSGTSGKAGWTKAGLTQRDLARARYRCLEEIESVRYSLQDL
                     EYAGKHLKWLTRGGKRLVTQLRDALTSMERGIQEYEQRVSASAFGPALRRHRIELAQA
                     RETLSLM"
     gene            complement(69442..69669)
                     /locus_tag="PK063_03040"
     CDS             complement(69442..69669)
                     /locus_tag="PK063_03040"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96044.1"
                     /translation="MTCTRCEGLMVMDDLVDLQESYHPMRLRGHRCLSCGNVVDTLIQ
                     RHRMVQNSHLRPVPASVPEKPVLFELIRRSA"
     gene            69882..71456
                     /locus_tag="PK063_03045"
     CDS             69882..71456
                     /locus_tag="PK063_03045"
                     /inference="COORDINATES: protein motif:HMM:NF017633.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HMZ96045.1"
                     /translation="MGQKWVESATQPATFPPPVRFREIDRANQEWPKRHRGQKMALTA
                     TEIGSIVQELASALADGWIQKISQPLPDTLILEIRVPGHTRRLLYSLRDDTARLHLVH
                     QHLPNPPTPPSFCQLLRARIQGARIDTLQHMSGDRIVRLDLTSRDGPVSLVAELFSRN
                     ADLLFLDGEGLVLATLRHNKDRVGQPYQAPAAAPFRSSSHQAVVHEPDTQPQTDVDPF
                     PLSSRLEAFYREREAELSHQAQARERESGLRKHLKKLLRRMAALRQDLEQAGRYEPYA
                     RYGELLKANLGLLKKGQNRVAVVDYYDEQLPELTIPLDPTKGPQANMDAYFAKYRKFV
                     TAQREISPRIAAIEAEVQQTQTELETIKGGTWQPPSTEGQTAVRGTPALRRKRDREGE
                     SRGPFRRFVSSDGHPILVGRNARENDELTFGLAKSEDLWLHARGTPGSHVVVRLDKGT
                     EPPPETIRDAATLALLYSDLKKSGKGDVIYTRRKWVKKAKGQAAGAVTVTQEKSIYVT
                     LDKPRLDALKSRSAPR"
     gene            71565..73607
                     /locus_tag="PK063_03050"
     CDS             71565..73607
                     /locus_tag="PK063_03050"
                     /inference="COORDINATES: protein motif:HMM:NF025885.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HMZ96046.1"
                     /translation="MGTAFDTRDWFPILSALLQTNTLRQFDDRLQRELSQRLGCSVIG
                     LYLYSEMATAFSPVSESLRDPASPAYPIAQLPASGTIKEAAVLAGEAILTGDLSTSPW
                     TEARAIAPHISHGTSVLVSPIRMSCESVTGTAAKTLGVIAAVAPGKPGAFSEEDRIWL
                     DQLSRHIAPVLTAVLAAEERDTLVAINNQVVLGTLTLDNLIHSIQPILREVIHHDITG
                     LVRFVGEPHNRWFDIVACEGVDIDQDALRQFPFEQMAAAEILATGKPLLLTGHNQDRF
                     AEHRYFESLGVYSAMLCPLLVQGAPYGFLAIGSKRRNAFSERDLALTEQIGFHLSHAL
                     TNLSAYDQIRRLKDQLEQENVYLREEMGASLDLKSLVGDSPALQKSLRAIEMVAPTDS
                     TVLITGETGTGKELVAQAIHRLSPRRQKTLITVNCAALPPTLIESELFGHEKGAFTSA
                     TTRKLGRFELAHGGTIFLDEVGELPIDVQMKLLRVLEAQEFNRVGGSHTIRVDVRVLA
                     ATNVDLEQAIKRGAFRADLFYRLNVFPLRLPTLRERREDIPLLARHFAKKYGLRHRKP
                     VTRINSAALKALSAYDWPGNVRELEHLMERAVIVSRGSVLTIEELDGLGPSHERPSPP
                     RTLAEAERAHIVEVLVRTNWVLAGKQGAAETLGMKRSTLQHRMKKLDISRPPRHVS"
     gene            73783..74199
                     /locus_tag="PK063_03055"
     CDS             73783..74199
                     /locus_tag="PK063_03055"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6022 family protein"
                     /protein_id="HMZ96047.1"
                     /translation="MKFIVSPLTPESVGREIQAYVNERQRQLLPSGEVTSEGRRFSWC
                     GDILDFLADGLAERLAPLGITFTNPFPGPLRLMDEVQQPDGQHVRRFWTVALHRGCPI
                     ARVCTLFFHRHDQISLPQVPLVMAFSPDHTAGEDGE"
     gene            74196..75326
                     /locus_tag="PK063_03060"
     CDS             74196..75326
                     /locus_tag="PK063_03060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HMZ96048.1"
                     /translation="MNYVALRMLFGDRAKYLMLLCGLTFAVMLIVQQGSIFWGLMMWS
                     QSSISNINVPIWVTDPGIGQVDEVKPIADTAVDRVRSVSGVEWAVPLYKGVLRARLSS
                     GDYHQITLTGLDAPTLIGRPAEVLEGRFEDILEPDAVVLDQWAVERMGGPSVIGIGTI
                     FELNDKLARVVAIAKTQKSFTNIPVVYTTYERAIRYVPRERRTLSYVLAKAKDGIPAS
                     EVTSRIHEQTGLGAFSAEEFGWKTISWVLKNTGIGINFGTTIILGFIVGMAIAGQTFY
                     LFTVENLKQFGALKAMGTSTFTLARMILLQAFTVGLTGYGIGIGLATGFGFLSAKGGG
                     LPFVETWQLLLLVLLALLGICTLSALISITKLARLEPAIVFR"
     gene            75371..76078
                     /locus_tag="PK063_03065"
     CDS             75371..76078
                     /locus_tag="PK063_03065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ96049.1"
                     /translation="MASVAVQVRGLVKSFGTGETTVTVLKGIDLDVHFGELLLLVGES
                     GGGKTTLLSAIAGILDIDAGDLQVLGASLTNMTPGTRTSFRGQRMGFVFQQFNLLPAL
                     TAAENVAIPLLIQGLRRPEAVSRGRLMLERVGLGDRTEFLPRNLSGGQQQRVAVARAL
                     VNDPQLLVCDEPTAALDGPNGQKIMELIRDVGRAPNRCVIVVTHDSRVFHFGDRMAEL
                     TDGRIVGIHPIHPEATA"
     gene            76075..77067
                     /locus_tag="PK063_03070"
     CDS             76075..77067
                     /locus_tag="PK063_03070"
                     /inference="COORDINATES: protein motif:HMM:NF027890.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HMZ96050.1"
                     /translation="MTILNRVSVWLAVLCTAFAGWSVLTAGNTVPMPTPVVEPPRSPF
                     ETTVAASGIIEAANENVRIGPPSAGLVTKVFVAVGDAVREGDPLLQLDDRDLRAQLVA
                     RQAAIPPAEAQMEEQKYRIGDLDTQLKRLKSVRDSRAVSDDDVKRTWYAAEMAKRAMS
                     RFQAALKQVIAQRDETQLLLDRLTVRAPRAGTILQVNIRAGEFALTTGATEPLMLLGD
                     MQQLQVRAEVDEVNAPLVAPQRPAVAYLKGNTAQTIPLTFVRIEPYIVPKKSLTGDNN
                     ERVDTRVLQIIYRFERPAFPVYAGQQVDVFIERTPAGGPPQTQPVERRGEVSRK"
     gene            77064..78581
                     /locus_tag="PK063_03075"
     CDS             77064..78581
                     /locus_tag="PK063_03075"
                     /inference="COORDINATES: protein motif:HMM:TIGR01845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux transporter outer membrane subunit"
                     /protein_id="HMZ96051.1"
                     /translation="MNRWILASRAATAVLMTLTVSLTGCLQGKAYTRPSVDTPADWTH
                     VASGPLVSGTSPKTPDADWWKAFRNEELTQFVERALARNHDVRRAVSRVIEGRASVTT
                     AGAGLYPQVNVQSSYTNISISKNTLAGLGLATGQQPGPQVFARPGSSFDLWNGAADLR
                     WELDVWGRIRRGMEAASADAQAIEQDARAIALTLIGDVGQAYFRIRELDEQIEIAQRA
                     LALRRDSLEIITKRASVGLASDLDVKRTEVLVAESAGQIPDLVRLRTVEVHRLEVLTG
                     SAPGGLTLASMPLRKVVVQPDIPVGLPAQLLERRPDILQAEATLIAANARIGQARAYF
                     FPTFSITGQGGLQSAEFANWFTGNSANFSIGPSVTLPIFLGGTNVARLDAAESRYQQM
                     LEGYQQTILLAFREVADLLVSIQARAEQLTRQREQAVAATAAVGLAEVRYRKGLVNYL
                     DVLDAQRTMLAAETQLAQTERARLTDMVSLYKALGGGWSQPPGITSVPASSSMTR"
     gene            78772..79668
                     /locus_tag="PK063_03080"
     CDS             78772..79668
                     /locus_tag="PK063_03080"
                     /inference="COORDINATES: protein motif:HMM:NF024824.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ96052.1"
                     /translation="MRDGVRGQRLARPLYPASIILALGLVLPFSTQASSASQETSAAK
                     SGIAGTNLLEEEQILSTTDKITQPIDTDAEAMRHNDLGVAFVFKGDVGQAIDEFTHAL
                     RLQPNYFAAHLNLANTLLDIGRHDAAMIEFKEALRLKPDDPKTHNDLGVALKEMGDPA
                     GAIAEFKTVLRRNPTDVNAHNNLGVALKAMGDLDGAIAEYRTAASLQPNDVNAHFNLG
                     LGLMEKHQPDAAIAEFRTALHLRPNDAKIRFNLAHALAGLGQRMEAAQELRQYLRLEL
                     DTPANRRWLEQAEAKLRELEMP"
BASE COUNT        17851 a        24338 c        20654 g        16725 t
ORIGIN      
        1 tcaggtcgaa gagccgatct acattcggcc ggccgagcgc gtgaactggc tgtaagactc
       61 acactggcgg gagagggcaa cctctctcgc cagtgaagga ccgcagcaca acaaaggccg
      121 gaagttcgaa agaacttccg gcctttgtac gtttatcgac agcctgcatg atcagttcat
      181 atctttcctc acctcaacta atatcacgat cgtttaactc gactcttcca cgaacgtttc
      241 cgtactagag tgttgtcgct tcaagcaatt ttccgaatga gcagaagacc ttttccccac
      301 ataccgcata acgcctgaag cttcagcttt agccccctgt ttacgtcact cgttcatata
      361 gtcgcctggg tcgacggcat cgttccgtct gcaatctgtc ttgaggttga caggaatcat
      421 tgcgaccgct atactcttta cagttgagaa cggttatcag tatcgagaag ctattcgcat
      481 cgcccggccg agacaattga tcatcagtgg gagacgccac tcatgtatgt ctgcttatgt
      541 aagggcttaa cggaatcaga tgtgcgggaa gcgggtcgcc aggggcacct gaccacgaga
      601 caaattattg ctgaattcgg tctacgggaa aatggatgct gtggtcgttg cgccaaaaat
      661 atccacgaat tagtcgccct cgcgaaaagt cacctggaga atgcctgccg caatccggtg
      721 tcatcctaat ctcccagaca ggtccttcat tgtaggcttc agcgcacgcc acgttcttgc
      781 aatgcaaacc cgcgcttgac tgccccggca acgtcagcta cccgccggcc taattcccga
      841 gcactgccga gctcctgctc atcaattcct gggctattgc cttctgttgt ggcagaagcg
      901 ccaaatgccc cgccgccgct gacagtgatc atataatttc cgagcatcgc ggcaagaatg
      961 gagagcatgg tgagttcttt cccgctggaa atctgaccac cggtcgcgaa ggcggctcct
     1021 accttattct tcaatttaaa ctccggaaac acgccgaact tgaactgcca gtcatcgata
     1081 aacgctttaa cttccccagc catattggac caatagacgg gagagcccag aacgatggcg
     1141 tctgccgcaa ataactcctc agccgtcacg cttcctatac gccgaacgat gacctccgtg
     1201 tgaggcaccg ttcgagcccc ctcagcaacc gctgccgcca ttcgctcggt attcccggag
     1261 agtgagtgat aggccactag cacttgggtg atgggtggac tatcggccga tgagccgata
     1321 gtaggcccta tcagaatact agtcgcgcac aaaagcagca gtcgccacat ctgaaccatg
     1381 atggacctct tggtgattct gagagcaaga ctggtatcgg gggggccagg ccttgaacgg
     1441 cctggcgaga atctatgtct tccgattaga agacaagaga taagaaattc accatgcgga
     1501 acagccgcgt cctagcgacg aattacttcc tcgtccatat gctcttcaac tgacacctgg
     1561 gtcaatgtcc cgcgatagtc gcacttgtgg caccggattc taaattcttc gatccacttt
     1621 tcctgcacat aagactggcg gcacttcgga cagacaaaca cgcctcgcat gtacaccaca
     1681 cgtcgcgttt ctttcatgaa cagcctccct cgaagtcaaa ttgatatgcc gaggatggca
     1741 taggggccga cggaattgca aggcggcatc tctatctcca gaactcgcat cacctctgcc
     1801 ttgacgactc acaaacagcc cgttaggatg cggccatgac acaatcgatg gatcattcca
     1861 gccaaacacc tcactcgaca tggctgagcc gactgaccag ttgcttgtgg agcctcgcga
     1921 tagtagcgag cccctggtct ggctgggccg cagatctacc gactgaaact cttattgcgg
     1981 tcaaaatgcc gaatggtacc gtgattcagg cagaattagc ggacacggcg ctgaagcgtg
     2041 cacagggatt gatgtttcgt gagcgcctcg cagacgatcg aggcatgttg ttcatcttcg
     2101 gtgacgccca accttggacg ttctggatga aaaacaccaa aattcccctc gatatcatct
     2161 ggatggatgc gaaaaaaacc atcgttcata tcgaacgcaa cacgcccatc tgcaccagac
     2221 aagacgacgg gtgtccgcag tatcattcgg aggagggggc gctctacgtg cttgaactcg
     2281 gagcgggacg ggcggccgcg cttcagcttc agcgaggcgt caaactcagc tttaaacaac
     2341 cctaatcgga ctccggccgc tcgctatgtc gacttacgcg ttccccagaa aaaactctga
     2401 atacgttcca cgagagaacg tgtatgcgtg acgactgaca aggccgccgc atctctcgaa
     2461 agctgcgcct tcgctgccgc cgtaacggcc tgtcgacgcg cgacgacctc gccgattcgt
     2521 tcgatcaacc gccggtcctc ctgaaccacc tgcagcaaag ccgacttgct caccgcaatg
     2581 accgacagtt gcgtgacagc caccactgtg gccgaccgcg gctcaccggt caataaagac
     2641 atctcaccga aaaactttcc tggttccagt gtcgacaccg tcgtagtcag tccaccctgt
     2701 tctaaacgga catccgctgt cccagagaca atcacgtaca gcacttctcc aggatctcct
     2761 tgccgaacaa ttcgctcgcc aggcaaatac aactcccctc tcgcaccttc cgccagcact
     2821 tcgatttgct tcgtatcaag cgtggccaaa aaatcgaccg ctgtcagttt cgccatgatc
     2881 cgctcaatgg cgtaacgatc ttgagccgca tcctgtccat tagcagattg atgcaccacg
     2941 cgctgcggaa acggaatctc aatgcccgta cgagcgaaag catgccagat gtaggtacgc
     3001 atggcacttt cgatggaatc ccgttgcgag aaatcgccaa tcggaaactt gatacggtat
     3061 tggatggccg attcattaaa tgcagtcaca aaagcgctgg gtttgggatc cggcaacacc
     3121 cccgagactg aactcgcagt ctcgagcaac gtcgcgcaaa cctgttcagg cggggttcga
     3181 tacgcggcat cgacaaacac gttgcaaaaa tgcgtcgtcg tcggtctggt gaaattggtc
     3241 acgccgcttt gaatgaccag gtcgtttggc aacgacacca catcatgggc acgggtcaat
     3301 aaggtgacat gctccatacc gatatgagtc accacccctt ctcgatcaag cactgtgacc
     3361 caatccccca ccttgacgat ttttcctagt tcaatcccgg agaaaaatct cgtcaacgta
     3421 tcctttagcg ccacgccgac catcgccgcc gctaccgtgg gcaacgccac gagagccacg
     3481 aggttgatcc ccatgaccaa ccagagaatc aacacaccgg ccgccacgac ttccgcgccg
     3541 atgagcaact gacggacgat atcagggatg taccgctgcc cccgctcgat cagccattcg
     3601 ccgatgatga gcacatcgag gatcgtgaag aagaagaacg ctgcgccgag ccaagctgcg
     3661 acattcaggc aggactgaat gaagtgagga acagaagtcc caagaccgct gtggccgatc
     3721 agtgatgcca caacgaaaaa gacgcccaca ccaccggcat aaaagggcag aacgggaacc
     3781 ggcttgccgc ggcgagtaaa cacgtaggtc agggcgccca ataccccagc cgcacaagcc
     3841 agaatggcca ggatggaacc ggcgagagat cccagagtca tgctgacatc acccaccgag
     3901 ggaaggatcg cacagagaga cctttcaggc tacgcccgct cctgccatga acgcatccgg
     3961 cgcacggtga tgacgccttc caccttctca atcgctttaa acaccctcga caagtgcgcc
     4021 gtgtccgcca cttcaacaat gaagtccagc atcgccttcc gatcttcacg ggtcgtaatt
     4081 tctgctcgac taatatttgc ctggcactcc gagatggctg tcgagacatg cgccaacact
     4141 cccgtcttgt ccactgcgat cactgacact ttcacggaat gcgtgctagg cgtcgattga
     4201 tcccactcga cttcgaccag ccggttttta tcgtaatcca gcgcttcgag gttcggacaa
     4261 tcaatcgtat gaatagtgag cccgcgcccc ctggtgatgt aacccaaaat ccggtcgccg
     4321 ggaacggggt tgcagcagcg tgaaagttgc atcaggaggt cgcgagcccc cttgacctgg
     4381 acccccgtat catccgtgcg accgatcacc ggcttgtgcg gcactggagc ctcaggcgcc
     4441 acggtctgag cttctcccgg caagggcggt gcaattttgc tcatgacttg agaagtcggc
     4501 acgtgtccga aacccacagc ggcggcaagt tcttccgcag tttcatatcc aacctgcttg
     4561 gcgaccgcga gaagttgctc tgagcgcatc atctgagcgg gagccagtcc atgccgccgg
     4621 aattcggcct ctagcagtcg tttgccgatt tcgatgctgc gagactgttc ctctgccttg
     4681 atccaatgct tgatcttcgt cttcgcgcgg gaggtgcgga caaacttcag ccaatcccgg
     4741 tggggtgttt gattggccgc ggtgagaatc tccaccatgt ccccgctttc catcatgtgt
     4801 ttgagcggga caatcttgcc gttgaccttg gcccctacac aatggtcccc gatctcagta
     4861 tgaacggaat aggcgaagtc gaccggcgtg gaccccttcg gcagttcctt caccatgccc
     4921 tgcggggtaa acacgtacac tacgtcgtgg aagagatcga gcttgaccga atccataaac
     4981 tggcgattgt ccggcaggtc ctgattccat tccacgaact gccgtagcca gctgaagacc
     5041 tttccgtcct tctcgtcgat acgtccgtgc tctttgtatt tccaatgcgc ggcgatgccc
     5101 tgctcagaaa ctcgatgcat ctcctcggtg cgtatttgaa actccacatg ctcgcccttc
     5161 ggtcctgcaa ccgtggtatg caacgactga tacatattgg atttcggaat ggcgatgtaa
     5221 tctttaaacc ggcctggcaa ggggcgccac agcgaatgga tcacgccgag caaggcgtaa
     5281 caattcattt tgatatcggt gatgatgcgt aacgctgcga ggtcgtagac ctcctcaaac
     5341 gagatcgact gcttttccat tttttggtag atgccataga gatgcttcgg gcgaccggac
     5401 acctccccat acaagccggc ttccgccatg gccttcttca ccatgtcgat cacttcatga
     5461 atgtactgct gccggtcttc gtcccgcttg gccacgcgca cccgcagcat ttcatagaca
     5521 tccggcttga ggtgcttcaa acagaggtct tcaagttcgt tcttaatcca cccgattccc
     5581 aagcgattgg cgagaggggc ataaatctcc agcgtctcct gcgcaatctg ccgtcgtttt
     5641 ccttcgctga gatactcgag ggtccgcatg ttatggagcc ggtccgccaa cttgatgagg
     5701 acgacgcgga tatcgtccgc catcgacaac accattttcc ggaaattttc cgcctgcttt
     5761 tcctcgtagt tccgaaaggt gatcttgccg atcttggtga cgccgtcgac gagatggacg
     5821 acgtcttttc caaaccgctg ctctagttcg agcggagtcg cgagggtatc ttccagcgtg
     5881 tcgtgcagga ggccggccac aatggcggtc acgtccgtct tcagatgggt caacaggccc
     5941 gccaccgcga ggggatggcg aaagtacggc tcgccggatc gacgcatctg cccttcatgg
     6001 gccttggccg aaaaatcata ggcccggcgt acgaggtcca ggtccgcctc gacgttatag
     6061 ctcttcaccc gctcgatcaa ttgatcgagt tctgtcactg tctcgtgggg catgcttagg
     6121 acacctcgcc gctcatgcgc agcgccttga tgcgcagttg gacgcggtca tacccgttcc
     6181 aatgattccg ctcggggcta aaggccagat cgaccggcct ccccgtcttc aaccctagct
     6241 cttcaaatga gcccatgcga aagccgatgc tgtcaaaaat aaacgagcgg ccttgccgga
     6301 cgcgcaactt cagatgtttc tcaccgacga cccgggcttc gacgacatcg agaccacgaa
     6361 cggccaatgt cggttcggga ttgcccgcgc caaatggatg caacgattcg agttcctgga
     6421 tcaagtcgaa attgacttcc gtgagcttca cctccgcatc gacgtgcaag gtcggtctga
     6481 ccagactggc ggtcgcccat tgtgccgcca cctcacaaaa ccgccgtcga aactcttcca
     6541 atcgcgattc ttggatagtc aaacccgccg cgctcggatg gccgccaaag gcctccaaca
     6601 gatcccggca tgccgacaat ccttgataca gatcaaatcc ctccacggtt ctggccgagc
     6661 ctttccctag gcccttctca tccacagcga tcacgatgct cgggcgatgg aagcgatcca
     6721 ctaatcttgc ggcgacaatc ccgacgacac ccagatgcca gtgacgcgag cccagcacga
     6781 tggcagccgc cggttcatcc tgctgtagag aggctcccgc ctgcgccgta atctcttcct
     6841 cgatttgctg acgctgtcga ttcagttgtt cgagctgttc tgcaatctgt tgggcttctc
     6901 gatcggattc ggtagtcagc agttgcacac acagcatggc atgatccagc cgacccgcag
     6961 cattcaatcg tggccccagt cgaaatccga tcgtttcgct ggtacaagct tttgtgatgc
     7021 cggccacctg tttcaaggca cggattccgc agcgggcacc acgattgatc tgaatcagtc
     7081 cctcgcgcac cagaatccga ttctcatcct gaagcggcac gatatcggcc accgtcgcca
     7141 gcgcgaccaa gtcgaggcag gattccggat cgacctcgcc cgagccatac cgtcgctggt
     7201 aggccgtgac caccttatag gccaagcctg cggaacagag ccccttaaat ggatagatgg
     7261 cgtcgcgtcg atgcggattg agcacagcaa gggctgcggg catcgtcgca tcggtttgat
     7321 ggtggtctgt caccaccaca tccatgccaa gttctttggc gacggcaatt tcatgatgcg
     7381 acgtcgtgcc gcagtctgaa gtgacgagta acgtcacgcc ttcctgtgcc agcttcctga
     7441 cggccccctc gttcaggcca tacccctcgc gtacccggtg gggaatgtat ccgcaggcat
     7501 tccctcccaa tcctcgatag aacgacaggt acaggctggt ggccgatacg ccgtccacat
     7561 cgtagtcccc atagaaacac acacgttcct cacgggcgag ggccnnnnnn nnnnnnnnnn
     7621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7681 nnnnnnnnnn nnnnnnnnnn nnnntctgga ttccggtctc ctctcctgtt tctccatcgg
     7741 agcacctcca gttcatccgg acgcattcga acgaccctct tctgtcacct tactctaggg
     7801 tccttgaacg cgtcaagccg acccacgaat gtgtgcgtcg tcgtcgctgc atatccgcga
     7861 cacgcggccc gcgagcctcc tcatccgtcg ccagaaaaac atacgccggt ataccatccg
     7921 cctatttgac gatcaaggag acgatcagca acgccacaat gttgatcact ttgatcatcg
     7981 gattgatagc cgggccagcg gtgtccttat agggatcgcc gaccgtatca ccagtcaccg
     8041 cagccttatg cgtatccgtg cctttcaatc cctgctcctc gatatacttc ttggcattgt
     8101 cccaagcacc ccctccactc gtcatggaaa tcgcgacgaa cagtcccgtg acgatgctcc
     8161 cgaccagcac gccccccagc gcttgcggtc ctagaatcac gccgacaatt atcggagcca
     8221 cgactggaat caagccggga atcatcatct tggcaatagc cgcctgagtg acgatatcga
     8281 cgcaagtgcc gtactccggt ttgccagttc cttccatgat gcctttgatg gtccggaatt
     8341 gacgccgtac ctcctccacc acgagaccgg ctgcttgacc gacggctttc atgcagagcg
     8401 cgccgaaaat gaagggcagc atgcctccca gaaaaagccc gaccagaacg gacgggttag
     8461 agaggtcgaa ggtgctggct tgcgtaccct tagccacttc acgggcaaac tctgcaaaga
     8521 ggaccactgc cgcgagaccg gcagaaccga tcgcataccc ttttgtcacg gcttttgtcg
     8581 tattgccgac tgcatcaaga ggatccgtaa tgtcacgcac ctctttgcca agatgcgcca
     8641 tttcggcgat accgccagcg ttgtccgtga tcggtccgaa cgcatcaatg gcaaccacga
     8701 taccggccat cgacagcatc gatacggccg ccaccgcaac gccgtaaagc ccgcctgacg
     8761 ccgccccccc gcaaatccaa tagctagcga gaatggccgc tccaatcacc accaccggcg
     8821 ccgctgtcga ctgcataccg acggccaacc cggcaataat gttcgtggca tgccccgttt
     8881 cactggcctt cgcaatatct ttgacgggcg catacgcctt agatgtgtag tagtccgtaa
     8941 tgaaaacaag agccagcgtg actgccagcc ccatcaatgc cgccaggtaa taactgatac
     9001 cgctgacacc tcccacaccc tccatgatct gcgacgtgat cgggaaaaat gcgaccgcgg
     9061 caatgcctcc ggcgacaaac aagcccttat agagcgccgg catgatttcg ccaccgggac
     9121 tgactttgac aaagagaatg ccgatgatcg tggcaaagat ggtcacacca cccaaagcga
     9181 gtggatacag aatcggcgca ttgacacctt tgaacatcgt aaacgccagc accatcgctg
     9241 ccacggtcgt gactgcgtag gtttcaaaca agtcggccgc catacccgcg caatcaccga
     9301 cattgtcgcc tacgttgtcg gcaatgaccg ccgggttacg tgggtcgtcc tccggaatcc
     9361 ctgcctcgac tttgccgacg agatccgcgc ccacatccgc cgccttcgtg tagattccgc
     9421 cgccgacccg ggcaaacacg gagatcaaac tgccgccgaa gcccagactg agcaacgcat
     9481 gaatggcttt ctcctgacct gccaactgag aggcgagagt gtagaagctg gtgatagcca
     9541 acaaccccag cccgatcaac aataatcccg tgactgcacc tccgcggaag gccaccgtca
     9601 gggcagcatt catgccgtta tgcgccgcct gtgccgttcg cacattggct cgaaccgcga
     9661 taatcattcc gacgtatccg gcgagcgccg acgcgccggc gccgatgagg aatccgactg
     9721 ccgtcaacat gccgaactta tcggatacag ctcctgcgcc ccacaagagg acaaacaaca
     9781 cggcagccac cacaccaacc gtcttgtatt gacggttcat gtaggcgccc gctccctcct
     9841 gaatcgcttt cgaaatttcc tgcatcttcg tgttgccggc attcagcttg aacacccaca
     9901 tggcgagata caggccatag gcaataccgg ccaccgccgc aaccagagca aaggtcacaa
     9961 tcgctgagtc gctcacagtg ttctcctcct gttacagatg gtgaaactga gaatccagct
    10021 gacgtggtac gggatcgatt cgccgtgaaa agctcactca catgtaagga tcgatgaatg
    10081 tcacaggtgc tccgtggctt gagcccatcg cggactgatt gtgcagcagg aataccgccg
    10141 catgcccgac aactgacacg gtcgcgaacg agaggaaaag tggcgccatt ctataggggt
    10201 gatcgaggct gatcaaggcg aaagatcatg cagcaagagg cggaacggca gcacgcaggc
    10261 ggtttgcgca aggatatcca gtttgttata gtgcgcgcgg gctgtggagg acgaacatgg
    10321 gattcgcgcc ggaatacatc ctgatcgatc agcagaagtt cagcaaagcc aagctgtcgc
    10381 tggacaacca cgtctacaag aattgtgaga ttgacgactg cgatgtgtat tatagcggcg
    10441 ggcaatacga actaatcgac acgcatatca ccaactcgcg actgatcttg aaccatcctg
    10501 ccaaagggat ctacagcgca attcagatct tcaagatgaa atcgccaggc tccagtatca
    10561 tctccgaata attcgttgca cgtgagacgc cactcagcgg atcgaagcct gagtggctct
    10621 cgtcccgctt ctcagccgtt tccccatttc acgctcaacg ccagacagct atttcgcaac
    10681 cggaacattc tcgctgaatt tcgcgattgg aatgggctgg aacaccggat cctgcgcacc
    10741 ctttgaagac tcggcctcga tacgttgcag aaagctcgcc gggccggtca cgggagcata
    10801 gctgaggatg gcttcgacat cgaacgtttt cgtgtccttg ggtgtcggaa aactgaaggc
    10861 ctcgacgcga gtctcctccg gcttgagaac cgtttcctca aggaccttca ccgcctcaaa
    10921 atcgaatacc gtcttctgac ctttggcatc cgcataggtc cgtccgtaga cgcgcttgtc
    10981 gctgaagacc gtcttgagat ttttcccttt caccgtcagt tccaaaacca cgcttgccca
    11041 tccgggatgg gtcgtcggca gattgtgagg gacgagactc tgcaccgcca ccgtcacgga
    11101 tgtcttgtcg ccctccactt tggtcgccac gtccaacttg gccgcttcct gcctgagctg
    11161 cccgatacgc ccaggaaatg tatggttggc aacctttcgc ttggcttcgc cattggccga
    11221 ctctcccacc tgttcaggca tatgacaggt ctggcattcc tttccggact tcacggcctt
    11281 gctttgatcc caattcccta acaggtcatt actctttcca agatcagccg ctacaggcac
    11341 gacttgatgg cagttcaagc agagatcgga tttgtggaac agggccgatt ccatcgattg
    11401 atgggcgaga ttcgccgcga aatctttgta cggcccatac atggttttat tgccgaggtc
    11461 atacttcggt tccggcggct gtttggttcg atcaacttgt ttaatgagat ggcattgcgc
    11521 gcaggccaca ccatctaagg agggctcacc ggattgggct tgagtgacaa ataactgcac
    11581 gtgatcggga aactcacgca catgcggcgc atgacagcgg aaacagaggg ccttatcttt
    11641 tccagcagga gacgtcagat aggcatccag ggcagcgcgg aatgtcggcg tatggatcga
    11701 tttggagaga ggcgatgtct cccactcctc aaacacccgc tcatggcagc gcttgcactt
    11761 accggaactg ggaaaggact tttcgattgt cagttgagat tttgcatcct gcgccaagcc
    11821 ttgctgcacg ccataactgg ccaatccaat caccatcaac aatgccatga tgatgagtcc
    11881 ccgcaacaga cctcgtcgat tctccaccgg ttgcatatcc tccgcacatg gtgcacacct
    11941 cgctgcccgt tgtcgtgaga accggcaggg ggtcttacag tgatttggtt cgataggtca
    12001 gcatgcgagg ctgaatatat tcctcgatga ccttcttggc ggccgcacgc tcctggtcgg
    12061 tgggcagcgt ggccagatat ttggctttca gttcaggttc aggctccggg atcaacgcgt
    12121 agttgagcac gacttcaatg gtcgacgcct cttctcctcc agccggcagg gtctgcgaaa
    12181 agggcactcg cctggtgttg ccgcccttaa tgaaggggtc gggaatcgga ccgcgtaaaa
    12241 ttttctcgta cggcaacccg aaatgtttag tttcttctgc caggatgtgc ccctgcgcat
    12301 ccttgatcgt gatcgagagg aagaattgct tcaacaccgg gtcgccatca gggaaactat
    12361 gcggcaggct gccgaccttc accaacaccg tcccttctac ccctgttgcc gccttcgtcg
    12421 cttcgatatc aatacgcggc atccattccg cctgcagatt gcgattcttc aggagcgtgc
    12481 ctggaatgac gacgccgcga aaccaatgcc gtccgattga gcgggtcatg gcaccacgtc
    12541 tcgacgtcga actcccggtg gatggctcca tatggcaatc ctggcaaatc gtaccgcgca
    12601 gaatttctcc ggggagatct ttctgcgtga catccttgac cttatcgaaa tggcaggagg
    12661 tgcagaagtt cgcgccacgg aacagcggca actgtgtcgc cggatggacc aaattttctt
    12721 ccggatccgc gtacgggccg tacagcatct cgctcggctt caccttgtag gtcggcggag
    12781 gcatgggtgc ggtctcgact gcatcgatca gatgacagga cgcacaaccg atcccttcca
    12841 cctggggctt gcctgagaga acctgcgcgg taattttttc ggcatgttgg ggaaagaccg
    12901 tgacggccgg cgcatggcag gatagacacc gctgccgttc ttccagcgaa ggattggtct
    12961 gcatccagac gcccaacacc gtgcggaaca ccggagattc aaaggaagtg ccgtgtaata
    13021 acgccgcatc cactcgaccg aaggatttca ggtcgggcgt ctgctcccgc atgcccttcc
    13081 attcttcgta gtgccgatcg tggcactgtt tgcaatcttc agaacggata aagatctttt
    13141 cgatctccgc cacccaatcg gccggggctt gaccgtcggt cttttgcgcg atagcccgct
    13201 catgaaaggt gaccgtgagc agcgcaaata ccatcagcag tccgctcatg gcccatttct
    13261 gaatggttcg tcccgttccg atcacgtgtg gctcgctctc ttaatcccgc ttgcacccga
    13321 cgaaatgaaa attcactccc catccgaccg gatcgcctgg atcggcgggc tcgtaggttc
    13381 ccaccgtaaa gttacattcc ttcatggcga ctttgaccgc cttgccgaaa tcaatcaagt
    13441 tgcggacttc cttcttatca atctctttga taacggagcg caccttaatt cccgcatagt
    13501 cagcccgcga attgccgatc acctcgaaga cggcgacacc ttccggccgt tgaagtttga
    13561 gctccttttg aacctcttcg tcgacctcac ccaccgcaat gccgaactcc tctccaagct
    13621 gaatggcttc ctccactgtc atttccccat tgctgcctga gcctgcggca atcgaaggat
    13681 tcccgaccgt ggcggcaagg agcagcgccg ctccacacac acaaagagcc cttccgaaag
    13741 aaagggctct gttgtgcatc acgcgatgaa tctgaacact gtcctccaaa agctggcctc
    13801 tacctttgcg aacaaagctc tcgccgatgc gctcggcttt ttacatcatc ctaccaggaa
    13861 gaattacgtc tttgtgaccg gatccaatgc aagttgaaac cagggagcga tcgccttttg
    13921 cccgttccgc tctttgttct caccattcca cacggcgaag gacacggctt gtatgtgccc
    13981 gggaatcagc ttcgcttcat tctcctgctc ttcactcgag aggggacggc gcatcacgac
    14041 acgccacgtc ccgtccttcc aggtagcttt tccctgaaca cgaccctgct tttctttcgt
    14101 ggtcaacgta ctaaacccgc ccccgatcaa atcctctacc gaagaggccc gtcgtggaat
    14161 cacctcaaac cgccggggct cactgccgcc ccccttgtct ttttcggtgg ttctcgatgc
    14221 acgccgatcg atgtcgctct gccaatcagc tttccagtgc cagatattga tgtaatggtc
    14281 caattgtccc atacaaaaaa acgccggagc gtcaccaagc ggaagtccca aagccacgcc
    14341 atctcgaaat gtgccaggcg tcaaccgatc atttttcgta ttgtcctgcc attccagcaa
    14401 gaatgcgatg tcggtaccat tgtgcacggc gcgtaccgtc aacgcgtggg ctgtcggctc
    14461 cggccagacg gggcgggtaa tgatctggcc gctcagtggc aaggtcatcg gggagatttt
    14521 ctgccagagc ggatcttccg gcgccacggg tatgtctccc gagacggcct gcgcacggat
    14581 gatcatgcct tcggaactga caatggggat accgagacca cccagaatga gggcgagaag
    14641 caacaacacg gagaggagac tcaacaatct ggtgcgggat gtgtggaccg acgtcattcg
    14701 cctcatgtcc cggcgcgtgg ccttagtcgt gacaacacgc gcacgcgttc cctgtgcggg
    14761 agccttggct ccgtcctcca agcgttacca caacttggcg cgacgaatct tattttcacc
    14821 ccgctcgcaa atatacagat atccttggga gtcgagcgtc aagcccacgg gggaattcac
    14881 caccgcctca atagcgagca acccgtcccc gtgtttgagc gcgccggccg catctttcgc
    14941 gacaaagcgg gcagcgccgc agccacccat attcttatca tcatatccgc tatcgccgtt
    15001 cccggccacg gtgctgatca tccccgtccc cgcctcgact ttgcgaacac ggtggttgcc
    15061 ggtatcggag atataggcgt ggttgtgttg atcgaacaca atggcttcgg gtgcgtgcaa
    15121 catcgacttg gctgccggct tgccatctcc gtcgtaccca tagcggcata cgccggcgag
    15181 tgtcgaaatc agtccggtct ggcgatcgat cttgcgcacg cgattgctgc ccttgtctac
    15241 gacatacaca tccccggcat tgtcgacggc aattccgacg atatcataga gacgcgcttc
    15301 tagagcgggc cgaccatcat ccagatacat ggagagattg agcccgtcag aacagaccgg
    15361 catcagccaa ccgttgtcgt cgctgaaatc gataccgatc gcatcgccgg ataacacgac
    15421 caaattgcgc gcaaccaagg gttgctccct ggcttcgtcc tcagcagtcc agctgccggc
    15481 aatagtttcg acacggcccg ttcgtggatc gaaccgacga atccggtgtg cctgcgtgtc
    15541 ggcgatatac atgacatcgt ccgcatcgaa cgcgatggcg gcaggccacg tgagattcac
    15601 ctccagcgcc ggtccgtctc cattaaagcc atgttcaccg gtcccgacga ccgtcgtgat
    15661 gatgccggtc tcccgatcaa tcttgcgaat ccggttgctc cctgaatcgc acacatacag
    15721 atcgttcttg gaatcacagg ccacatcgag aggcagatac aagccggctt ccccacaagg
    15781 cccttcgtct ccgctgtagc acgtctctcc gatgccggcg aagttatgga ccgtaccttc
    15841 cgtcaagttg acgcgacgca cacgatcgga tccggactcc gcgaagtaca gccactgctc
    15901 ctcccgatcc agagcgacgt ggtgcggaag gggaatgccg gccttcaccg cgcgcttgcc
    15961 gtctcccgta ctcctggcct ttccattccc ggcaaaggtt tcaatgtatc cgggagctaa
    16021 ctgaacatct gtttccataa cgttgtgcgt ccgttctatg ctgggccctt gttatcgagg
    16081 atattatgct tgtgcgcgcg cggcaggagg ggccgcagcg acttgttgct ccaccacagg
    16141 cgtcggcatc ggagccggcg gttgggcggc aatggcctga gcctgcacgg gttcggcctg
    16201 ttgctgcgct tgcgcctggg cttccgcttc gatcgcatcc gcttcatgga cggatttttt
    16261 aaagcccttg atggccttgc cgatcccctc accaagctgc ggcaacttcc ctgctccgaa
    16321 aataatcaac acgataaaca ggatcaggat caactctgta aaaccaaggc tgccaaacat
    16381 ggtgtgtctc ctttgctcac gtgttcagga tgcggatccc tctttggcct tcttcgcaaa
    16441 tcgttctttc aaccgctgac gagcctgctc ggcctgttca aacattttgc acttatcgta
    16501 gacgctgatc aaattgtaat acgcgagcgg ctcgtccggg ctgtgctcca ccgcactctc
    16561 catcaccttg atcgccaaat cggtctttcg gtgattgagc gcgatctcca tcaacttgaa
    16621 gctggcttcc aggtgcttcg gatccagttc aagaacacgc aggtaacact gaatcgccat
    16681 gtccatggtg ttgtagtcgg agacttgcgg attatcgagc tcgacgtaaa cgccagcgag
    16741 attgtaccag gccatgggat cgtccggcgt gatctcgacc aggcgttcgt aatagttctt
    16801 cgactccatg tacttgcgct tgtccgcctg cacccggccg agattaaaca gcgccaagac
    16861 atcataagca tgcacctcaa gcgcacgctt aaactccgcc tcggcctcat cgatcatgcc
    16921 cttcgtagca tagatggtcc cgaggttgga gtagtacatc gccagagagc gattcatctc
    16981 cgtcctgagg ccctcggcca tctcgatgga cttctttact tctgtaaggg catcgtccaa
    17041 tcggcccttg ctgaagtaca gttcacccaa tcggcagcgt gcctgaaaat catcgggctc
    17101 ggtgctgagc agcttttcaa tctcagcaat ttcttcatcg ggatttaacg gctgatcgcc
    17161 aggatctacc gccgcactac cctgttctgt tccgccggtc tgtgtgtgtt catccataac
    17221 aacgtatcct aatctgggtg agtcaaaaat taaatctgtc cgccaacgag ggattcctgc
    17281 gtgccgacca ggggcggtct actcaccgtc gcctgctcgg tgaccgttcc cttagggcga
    17341 tcgagcgtca ataacattac cccaagaatc accatcaagg tcaaactgga aaacagcagc
    17401 gcataaccgg cgataaacat taaggccagt ccgtagcctg ccaggcgccc catcgtcacc
    17461 agcctaatga cggtatacga ccagcacaac agtccggcga cataaaaggc gaagggcaga
    17521 tagaaggtat agcccatgcc catttggaag atccagctga tcccctcgcc ggccttccgg
    17581 atggaatggg ccagcaccgg gttgtacaac cccaggaaat aatccataaa caacaggccg
    17641 aaaaatacca ctgccgacac tgccccgaac cagatcgcgc ggcggcgctg ctgtttgttc
    17701 ctcgtgcgga acgatactcc gcgtccgtag gcccaaaaga ccaggatact agccagcacc
    17761 atcaacgctt cgccgatacg attggcttca tagacaaacg gcggtgccgc aatcactccc
    17821 atccatccgt aggtggtgga gaagatttga tagtacagcc atccggaaat cccgaaataa
    17881 tagacggtgc ccatgacgcg cttggaccac tcctgctgct gcgagagata ctccagcatc
    17941 agcgccgtga gtgcgatgat ggtcacgacg ttgtaggcga tcgagccgag catggccggt
    18001 tgcacgatga gaaaggccac cgtcaacacc agcagaagcg ccacgctggg gatagtgacg
    18061 gcattaaaac ccgtgagccc tcttgcgcgg gcacgattga ccagcaagac cacgagggca
    18121 aggaacacaa aaatggccac gacattcagc agcgcaaacc caatcgaggt cagcagctgg
    18181 aagaccgttc caatccactc atgctgagcg gcaattttgc tgatgtgcat gcccagacgg
    18241 gagaccagac gatatagcac cagttcgaaa aagccgacga acaacaccag cttgatggtg
    18301 tattcaaaca acaatccctg atcgtcaact cgtcctgttg gccgttcgac ggcggcggct
    18361 atagcagaca tctccagccc ccctggcaaa cgtgaagcac ttcgtgacca caccgcatga
    18421 ggccgcactc tgcgcggccc gactttccaa tctaggagac ggtaggttgt ggtatctgca
    18481 acgcttgcga cttagcccgg gcaatataca gcagcccgtc ggccatagaa tagttaaacg
    18541 gcaactcgca cacgacttcg ctgatcttct cgtacacctg ctgatagagc tgctccgcct
    18601 gagccggcgt catcccttcc tgcacttcgt agaaaaaccc gagactcaaa tcctcggtgg
    18661 ccggtcgcat aattcgccga atgccataac tccccggatc gctcatgatc ggcgcttctt
    18721 tttccaagtc aaacaggcag ggctggcaag agaatccata tgattcgtgg agcttggtat
    18781 tgcctaccac gaagttcatc gtttccagcg cttcctcctc cttctccgtg gggaagccca
    18841 caatgacata gcagtgcacc gcgatgccca gatcgacgca gtcatccaca atgcgccgaa
    18901 cggattcctg cttgatccct tttttcatga agtccatgac acgctggttg aacgactcca
    18961 gaccaaagac gatcttcaag cagccggcgt cccgcatctg tgtgagcaat tctcgcgaga
    19021 gatttttttc gaacctcaat tcgcaggtcc actttacatt gacctgacga tcaatcatct
    19081 gctggcagag ccgcttcgta ggcgacagtg cgaagcattc gtcggtaaag aaaaacgatt
    19141 gcgcgccata ccgttccttc aaccagacca gatcatccac cgtcttgccc ggatcgcgct
    19201 gccggaagtt ttgatgatcc agcgtcaacg cgcaaaacgc gcagtccttg tagtaacagc
    19261 ctcgcgaaaa ttgcactggc agtaccggct ccggagacaa atacaggtcg agcggaaatc
    19321 cgtcgtagtt gggcgccgtg agttggttga tattctcgga gtagaacggc tgattgacgg
    19381 tgatctttcc attctgacga taaatcagat tgggcacctt gctaaagtca cgcttgccat
    19441 ccatctgatt gacgagttcg agcaaggcgg tttcaccctc gaacaccaca aaatcgtcga
    19501 cgagatcgaa gagccatggg cagcgtcgca ggttatcgac caggcgcgtg aaaatgctgc
    19561 ctccgacggt cacgtgcagt tccggcgcaa gttctttaat caatcgacaa agcgtgagac
    19621 ccgggatgat ttgcgacgta gccgtgatcg agacgccaac caaatccgga cgatcggtca
    19681 aaatagaggg caatacgtgc tcacggaaga gactgatgta gggattttgc gcttcgtcac
    19741 ggatagcttt gatcagatct ttcgacgaat agatggagta gtcaccaaac tgattatcca
    19801 cgacggtcat tctggtgggg aaatagagcg atgacagcac ctcgagccac ttatcgatta
    19861 gaaagaggct gttgcgatag gcttcgatgt catagaagcc ttctccccgc aatgtctctt
    19921 tggcaagttc gatacgttca aacaagtagg ggaagcgatc aagggattcg ataatccgcg
    19981 caagttgctc cgcactcccg ggcccagttt ctcccgtacg ttctcgctca aggcctcgct
    20041 gcttctcgac caactgctga tagaggccgt gggcaaagga ctgggtgagg actttgtcca
    20101 gcaattcgat gccgagatca cgctgggaga catttttgac tcccgcttga gtgaggaaac
    20161 cagtgagaga agggaggctt aggtaaggtt gcgaagggtg ccacgtcggt ggaaacagga
    20221 gagaaacctt cataaaatta tctttatatt aagcaggaaa atcagtgttt tcaggagatt
    20281 tgtaccgtat cggtttatac actccgcttt ggtccgaaag caaccctccg actgtgatga
    20341 aaaagaaatt ccactgttcg cgccaatgcg tcacagagac ccagaaatgc acgaaggccc
    20401 cgagtcactt tgccatcgct gacaagaact cggggccttc tgcttcaagc cctcaacacg
    20461 ttccagcccg gcacaggggc aggaatttta cttcagaccg cttggatcac ggcaacttca
    20521 gcgtgaacca agtggagaga gacttcatac cgttccgttc aatgttggaa ccgtcccaca
    20581 ccgcaaacgc gatgggcaca gaggctcccg ccttgaactg ggtgtcgttg gcatcgccgg
    20641 tctccagcga acgcttcacg actacgcgcc aggtcggacc ggtgtatcca ccgcccttga
    20701 gggaacctga cggctcccac acgccattgc cgatcacatc ttgatgggcc tgggtggtca
    20761 aggtgctgaa cccgttggca ttcagatcct caacggagct gacgcgcagt gtcgggtcgg
    20821 acatgatgtt accggaccaa ataccggagt tgaatggccc aaggctgcgg ccgatacgat
    20881 ccggataggt gactccgcca gccggctctt cgaaatagta gtcccagaag atgccagggt
    20941 actggtcgtc cacgtcccag attccggcgc tatccttgcc gagatccttc tgccactccg
    21001 cgttccaacg ccagatgttg accgtcccac cggactggcc catgcactgg aagggcggcg
    21061 cgcccgcagt attgaccggg aacatgatgg ctacctggtc gcgaaaatcc tgcggaccaa
    21121 tcgccgtatc gttcttggtc tggtcgctcc aatcaaggcg caaccccaaa tccttcccgt
    21181 tgctgaccgc cttcacaaac accgacttga ccgaaatatt cgggtgcatc ggggtcgtga
    21241 tggtctgtcc gctcaatggg atgatgacac ctggcactcc ttcccagatg gggtttgcac
    21301 cgtccatcgg gattgccccc ttgatcgcct tcacgggaat ggtcaccggt tggctgaccg
    21361 cgagaggcac ctgcccgatc gtcaacataa tgccgacgat cagcgcagag aacagaatgc
    21421 caaacaccaa acgcttgttg cgtgtctgca ccagtctcat tgcgtatgcc ctcctctgaa
    21481 agattaataa gaaaaagaac tgggaacgta taacgtctac cgaaaaccga atactgcact
    21541 gcccgaaaac cgagaactcc tacgcagtcc cgactgggcc ttcgctcttc tcgccgtcct
    21601 tctcttttgt cttctggtcc atgaaggact cagcgccgac ttcgctcagc aacatactga
    21661 gctcattccc cttgtcctgc gccccgcact cgtaggtttg accttccgga gcattgaagg
    21721 tagctggtct atagtccgcc tcggagtatg gctgcacggt taccccaagg aaggcgacct
    21781 caaaatccat ccattccgac atacagtcgg caataagctt gaacagcccg gtgtctgatt
    21841 tttttgccaa catccggcag aacagcggca cccagcggcc gatgtggttt ttcacaaact
    21901 tcttttgcgc atcgaccacg atttccgttt tatcgattcc atcgtggcaa cgcgaatagg
    21961 attccttata cgtcaggaaa tgcatgaatt cgagttcgac actgaggtgg tccagacgtt
    22021 catgcacatc cttggaaagc tccaccccaa acgctttgta gaatcccgca atgtcaccca
    22081 tgacgtggga ttgcgcgaac acgtggtcgt tcccaaagag ggtttcgtag ggcgggcaat
    22141 ccagcgtgat cacattggtg aacacccgac ggtgttcggt ctgcagatcg ccaatttgcc
    22201 aattgacgca ctccgccgac accaacttct cgatctggtc gaattgcttc ttcatcaggg
    22261 caatcttctg aatggcacga tcgccaccga tgccgtccaa cgcgagccgc aacccgtcta
    22321 acgcagcgcg tccgtcttcg acgaactcac cacactgcag gtaatccaaa aactcctcat
    22381 cctccggata caacaggctc caggagaaca acaaatatat tttgctgcga ttgagcgcgc
    22441 gctcgacagc aggcgaatcc ttgatcggaa ctgccttggg gggagcaatt gcggtggagg
    22501 acggggaggt gggctgcacg acttgtttcg atgtcatacg tatcttgctc ctcacctcaa
    22561 catgttgcgc attttttgcg cacactacgc aacatctgag tcctgcggca caggaggcgt
    22621 atgataggta aaggagggag ggatgtcaag catgaactct ctctcctttg ccattgcttc
    22681 cgtgccgatg tttcatgaaa taacatgatg gatgaatgcc tcgacatttc ttaacacacg
    22741 actgattcag tagttaagac tgcccgcaga aagatttctg gccgggacga ctttgaccgc
    22801 aatgcggtca ttgacagtct tacaaatctg ctcgcacata ccacatccaa cacagcgcgc
    22861 ctgctccacg tcaagacgga gcgcatgaaa atccatagac agggcatcaa cagggcactt
    22921 cgatacgcag gcgtggcatc cctgccccgc cgtacaaaca cgatgagaca ccgtggcgat
    22981 gcccatccgc acttcgacaa catcagccac cggcaagagc gcatccgtcg cacatgcggc
    23041 aatacaggga aaatcctcac agagctcgca ggcgacttga ttggcgaaaa tcaccggagt
    23101 tccgttcgag agatcgctta cgatcgcccc aggaggacag gccttgatgc aatcactgca
    23161 gcgtgtgcag cgttcgagga aggtagattc gtcgacggca ccaggagggc gcaaccagtc
    23221 tgtccgcacg ggggctgccg gctgttcgcg aggcgcatcc ttatggatag caaattccct
    23281 cgccgccttg gccaccgaga ccacagaatc tttcaggaaa tcacgacgcc cgtatttggg
    23341 atcaccggcc atgttgcacc ccgactacat gacaccgtcg gcacgcaact tatagacttc
    23401 cacgcaacgg tcacaggctc cgtactcgac gtcccagcca ggatggtttt cacgaatgaa
    23461 gtccaaaatg tatggctcca acttcgtctc catatcctcg acccaggtat acgtcggaaa
    23521 tcggcacaag ggacagggaa accccggcat taacatgacc ttgttctggg tctccgggat
    23581 ttctccccct tcgacatcga cggcgcgatc caaaatgcgg agggtatcgg tcgccatctc
    23641 taccagctcc gaatgggtga agtagctcgt ctgccacaac ccttcgaaca cagacttcaa
    23701 ttgagccggg ggaattttgc gataccagga gcggaattcc ttgaaccgat cctccttttg
    23761 aagcatcggc tccttgcccg cagcaatcag acggctatcg acactgatat tccaaagaat
    23821 gcggtagcgg tgcagaatga gcgtttcctc gccggggttc tgtccaaccc tggtgtcagg
    23881 atcgtaccca aacgccggat ccaacatatc gttgatatgc atcagttcgt gacggcaata
    23941 gcgagtcagc gcgggatcgt agaagcggcg tggaatcagc ttaatcccga cgcccttcag
    24001 ccccttttcc tcgaattgct tggccagatc gtgctcgacc gatccccatt tgcgaagcac
    24061 gtcgacgccc tcctgatcct ccttcagcac acccttgacc aggacgactc ccactcgagc
    24121 cttgaggtcg ggaaattcgt tgaaggcgtc acggatgatg tcggaaaagc cccagatccc
    24181 gaataagtat tgatacagtt tcttgaactc cgcttcacga tcatccagcg taaatttctc
    24241 atagatcgga tcggccagtt cgtgaaattc cttgtagtag gtcggatccc cttcccgctc
    24301 ggttttttca ataaaggagt cgatgacttc ctgcagtaag gccggctgaa atcgaatttc
    24361 catggacggc ttggatactt ctactccggt agtcataaga cctcacattt tccgttacag
    24421 tgaagggaga aaccatgcgt aagcactgtg cttgacttgc tcacggtcct tctcttacga
    24481 tcctcaaaac gaccgccgat tatacaaacc cctcggcgtt ttttgcaaac cgcggagggc
    24541 tggccagggc tagatggccc tcggtcacac cagggacgag gcacaaactt ttatgagcaa
    24601 ttcaacgacc acgcccccga caattccttc ggccgcaccg gcgcccacac aaggggcaag
    24661 tgctcaagca ccggctatcg accatttaga gtattggaaa acaggcttcc gggaactcaa
    24721 aaccttccgc ggacattcgc atggcgtgtg gactgtcgcc tatgcaccgg acggtcagac
    24781 gatcgtcagt ggcggcgtgg atcgttacgt tcgaatttgg gacattgaaa ccggacgtct
    24841 tctgcgctcg ttgcgcggcc atacggccga tattcgagcc ctggtcttca cgccggatgg
    24901 ccgtacgctg gcctcaggga gcgaagaccg gacgattcgc ctgtggaacc cgaaaaccgg
    24961 ggagccgacc aagctcttgt ttactcgcta tgatcacaat gtgtgcagtt tgtcattgtc
    25021 ccccgatggc ctcatgctgg cccgcggcag ccacaataaa gacatcaaga tctgggaagt
    25081 cacgaccgga accgatctca tgacgcttct gggcaaggat caatacgacc accattggtc
    25141 ggtctgcgtg gccttctcac cggatggcgt gcacctcgcg agtggctccg acatcggcaa
    25201 aattcgcatc tgggaagtgt tgccgagcgg cgaagaaaaa atcctccata atggacattg
    25261 ggaggaaacg gctgaagatt cgacggaaac gcgcggcttc ttcatcgagg atgacggcgg
    25321 atttcaaaaa ccgatggagt tctggatcgg ggcgatgacc tttacgcccg atgccaagat
    25381 cctgattacc ggcagccggg acaataccat ccggtttttt gaaatgccga ccatgaacga
    25441 actccgcgtc ctgcgcggac acaatggctg ggtgcgctcc ctgaccgtgt caccggacgg
    25501 gaaagtcctg attagctccg gtgacgacaa cacgatccgg ttctgggaca tcgccacagg
    25561 ccggaacttc cggactgata aaactcacac cggccccgtg cgcggagtgg ctctttcgcc
    25621 tgatggactg cgactggcca gcgcttcctg ggatcgcacc gtgaaactgt gggaaggcgg
    25681 tcaagagccg gcagagtaat ttactcgtct ctctcctccg cctcaccctt ggcggaggag
    25741 atgccatacc gcttgcactt gtcccacagg gccttcctgg acaatcccaa taccgcagct
    25801 gcgcttgtgc gactgccgtc tacctgcttc aacaccgttt caatgtagtc cttttcaaag
    25861 gcttcccgcg ccgtcgccaa tgtggtagcg gcctgtgccg caggttcgtc agcctttgca
    25921 gacaggccct cgtcgcaaaa cccgcatgtc gcctgaggcg caccaccgag atacgggcag
    25981 ctttggaatc cacaaaggtc ccagggctgc aaaggctccc cgtttcgccc caaggtcacc
    26041 gcccgctcca ccatctgctc taactcgccg acattgcccg ggaaagaata gtgtagaagc
    26101 aagtcgcaac tgggctgaga aaaccccttg ggggatttat tgaggctttt tgatcgcagc
    26161 tcaagaacgt gctcggcaat gaccagcaca tcttcccgac gctcgcgcaa aggcggcaca
    26221 accacctgaa cggcagcaag gtgatcacag aggtcctgac ggaaccgtcc ctgcgctacc
    26281 gcctccttca aatcctgccg cgaggcgcac aggattcgaa catcgagctc gatcgattca
    26341 cgccctccga cacgctcaaa cttccgttcc tgcaggaccc gccatagctt gctctgcagg
    26401 agaggagaca gcgaatctac gtcgtcgagc agcagggtcc ccttatgtgc gagttcgaac
    26461 cgtccccgtc gctgccgcga ggcaccgggt accgccccct tttcatggcc gaagagctcc
    26521 gcctccagca gatgatccgg aaggtcggca caacacattt tgatcaaggg ctgatcgcgc
    26581 ctggggctgt ttaaatggat ggtatgcgcc accaactcct tccccgttcc acgttcaccg
    26641 acaagagaaa ccggcgaatc agcggccgca atgagcttga tcttgtccag cagcgcccgc
    26701 atctgatgat tgcgcccgtg gatgccaccg aaactgaaac gatcctccaa cacttctttc
    26761 agttcgagat tttcccgccg caacccgata atcttgccga cgcgctcgac gatcagcagc
    26821 aattcgtcca tctgaaacgg cttggtaatg taatcgtacg cgccaagctt gatggccccc
    26881 accgccgtgt ccactgatcc gtgagccgta atcaaaatga cttcggtcgt gggacttcgt
    26941 tccttacagg tcttcaaaat cgtcaagccg tcagcgcccg ggagacgcaa gtcggtaatc
    27001 acgatatcaa actggcgcgt gcccaggaca gccacccctt ccgtgccagt cgcggcggcc
    27061 atgacctcgc acccgacccc ttccagcgca tcctgcatag agagccgcat cagcggttca
    27121 tcatcgacaa taaaaatctt gagccccttc acgaaaacct cccaatggcg tagcgttcgg
    27181 tcgagagagg aatcgacacc gtaaaggtcg tgccctttcc cacttcactc tctactacaa
    27241 tccgtccacc gtgccgctcg acgatgccta aactcaccga caaaccaagc ccggtccctt
    27301 caccttcgtt tttcgtggtg aaaaacgggt cgaaaatgcg cggcagaacg gacgaagaaa
    27361 tgccgcaccc ggaatcctgg acgcgcacga gacaatgagc ctctttgacc gtcgtgcgaa
    27421 tggtcagtac cccgccgttt cgcatggcct gaatggcgtt caaaacgaga ttcattaaca
    27481 cctgttccat catatgccga tcgatcatga tttccggcat gtcgacggct aggtccgtct
    27541 ccagctgcac ccgatgaggc acgaacaggt ggtcggttaa caacaacacg cggttgacga
    27601 cctgattgat atccgccagt gccagctccg gattgtgctg ttgggaaaag tcgaggagtt
    27661 gccggacgat ccgctgtacg cgacgcaatc catcttccat cgacgcgaga tattcttcct
    27721 ggcgtgacgg agacagcgtg cccttacgca tattgtagag acagttcagg ataccaccta
    27781 acgggttgtt gatctcgtgg gccacccctg ccgccaactt gcccacggat gccagctttt
    27841 cagagtttct gatttgttgc tcgagtttct tggtgtcggt catgtcgcga gcaatgccca
    27901 ggacccccaa aatctcgcca tcgactccat gcagcggcga tacgctgacc atgacagaac
    27961 ggggctcgcc ggatttcgtg aggacttcga cctcatagac ctgcttcacg ccgatatcca
    28021 acgtcgattt taaccggcgc ccacgatgac gtttcgacaa cagccccaaa tatggccgtc
    28081 ccagcaaatc ttccttcgcg tacccccagg ccaatacctt gctgttgaca taggtaaagc
    28141 actgctcact atcgagggta taaatgacgt cattggcatt ttccagcagg ttctccagat
    28201 actgcttggt ctcttcgatc tcacgggtgc gttcgctgac cttggcttcc agctcctgct
    28261 ggtaggtgtg catctggcgt tcaaggcgct ttcgatccgt aatgtcacgc agctgcacca
    28321 tcacccacgt gtgatcgctg ccgcgtacca ggatcacatc catctccacc ggcgtttcct
    28381 tgccgccggc atcacggacc gtgatttcct gcgtgggcac ttgccgttcg ccggagtgga
    28441 tcttcgccaa cagcgaacgc atgtcctcgt gatgagccgg caggatgacg tcgagaatgc
    28501 tgtgccctac gacctgttgt tcggaatacc cgagcgcctg ctcttcacgc ttgttgactg
    28561 cgacaatcac gccgtcttcg cccaccatga acacagaatc ggccacgaga tcaaagagcg
    28621 ctttataccg ctcctgcgag gccaccagct gttgggtccg ctcattgact gcctgctcga
    28681 gtcgcgtggt gtagcggtga atttgttctt ccagtagacg ccgttccgtc acatcgcgca
    28741 caaaggcgcg ggagtgaacg agccctccgc cgatctcgaa taacgccgtc gaatgaattt
    28801 ccacgtcgat cggacgtcca tctgctgcca caaacaccgt ctcaatcgta ctacgcccct
    28861 gcgcgacgag tcgctccaga tacgccaata cctcagcctc acgccccttg gaaaccagat
    28921 cccagagacg catctgaagc atttcctcca gcgtgtaccc cagcttatcc aaaccggttt
    28981 tattcacatg tacgaattgc ccggctttat tcagctgata gatcatctcc ggcgaatgct
    29041 cgatgagatc gcgataccgc gcctccaaac gtcgaacatc ctccatacga tgttcgatct
    29101 gttcgaatga cacgcgcagg ttcgccgcca ttttattgaa ggcatcggca agctgttcga
    29161 tttcatcacc ggtcttaagg tccaactgct gatccaagcg gccactcccg attttctgca
    29221 cgccctcatg cagcaggccg atgggacgcg cgatgcgccg agcgaccgtc aggccagtga
    29281 ggaccaatac ggcaaagact ccgagcccgt agacggtcac ctgtacgacg agccgagaga
    29341 gaggcgcgta ggattcagca gggtcctgcc gcacaaacgt cacccagcgt ttaccgccca
    29401 gactctcggg tgtgagatca gcccccaggc gaaccggggc aaaaccgacg atcgaatttt
    29461 ttccgccatg cgaatcattc tccgcagtcg tccagccggc cgcactcgag ttgatggctg
    29521 caactaactc gggtttgacc acatgctctt cgggagacag gatcgggcag atcatcggcg
    29581 cgccgtcaga actgaacagc atggcatgtc ctgtctggcc gatcgtcgcc tcagagacgg
    29641 agtgaaacaa ggtatctcga cgcaagagca ccgtcaccgc gccgatggtc gtatgttgtt
    29701 catcgtcaat gattggcgcc gacacattga ccacatgcgt gccgaaggca gggtcgaaga
    29761 agatatcact gacgaacacc ttccccgttc cccgcttcat gaacgcctgc caccaggcgg
    29821 tcttgccgta gtagtactcg acctgcggaa tggaactgac cacgagcgcg ccgcggttgt
    29881 cggtcacgaa aatacccacg tagtccgttt tccggatatc gtgccagcga atcaaataat
    29941 tggtcacgat gcggttgatg aacagcggaa actcgctttg tttgtcccgt tgccgccagc
    30001 gctgctgcca ggctttgatc atcgactgga cggtcttctc gtccttgtcc aggtaagtgc
    30061 gattggattc ggtgacagag gtgcgaagaa acggtgtggc ggcgagctgc tgcgcttcgt
    30121 tgattccgcg cgtgacctgc atctcgatcc gccgggccgc ctctacggcg acttctttga
    30181 agttggcccc gatggtttcc ctcaaggccc ggcgttcttc gaggtacgtc aaaacaagag
    30241 aaagacccaa cggcaggaga ccgaccatca caatggctgt gatgattttc cgctggaggc
    30301 tgtgtgaccg gctccagaac agcatgcgtg cggatacccc gactaatggc cctgtcgcac
    30361 aggaggtggg gccctaggcc cggctctgac gagccgaggc ctagcgacgc ttcaggaggc
    30421 tccccgcgct gccgggccac agcagcagca atgggcttgc cacgaagatg gacgaatagg
    30481 taccgaacat gactcccccg agcaaggcca gcgaaaaatc gtgcaagacc tccgcgccgg
    30541 ccaacaccag cggaatcagc acgatcacca cggtcaaact ggtaacaatc gtgcggctca
    30601 aaacctggtt gatggcctga ttgatgatcg tttcctcgtc ttcccgccgg cgcgtgcgaa
    30661 gattctctcg gatccgatcg aacacgacca ccgtgtccgt caacgagtac ccggccagcg
    30721 taaggagcgc tgtgaccacc agcaaggtga tttctttatc caaaatgtaa aacacgccca
    30781 ataccgcgag gacatcgtgg aacgtcgcca gcgccgccgc gacgccgaat cgcagctcaa
    30841 atcggaccgc gatgtagagc acgatcccca cgaatgaaat caacacggca atcatggcat
    30901 cttcttggag cttctttcca atcgtcggac caatctccat actggaatcc accacaaact
    30961 tgttgccggg gaactccttg ctgaatacgg ccatcacccg ttccgcaacc ttctcctcaa
    31021 tggtcgtcga cgctttcaca cgaatgagca acttattgtc ctgcgtgaat tcctgcaatt
    31081 cggccgatcc caggccattt gattccaatg ctcgccgggc ttcgtcgatt ctgatcgatt
    31141 gatcgaattt gagttggact gccgtcccgc ccgcaaaatc gattcccaga ttggctgccc
    31201 cgcgcgcgat ttgaagcacg gcaataatac ccaggaaggc caggatgccg gatagcgcaa
    31261 acgagatcgt gcgcttcccc ataaaatcga tattcgtctt tcccaaaatc tcgaacatac
    31321 cggctccttc ctaaatgctg agctgctcaa ttttcttgcg ctgattaaag aggtcgaaaa
    31381 tgaccttggt gccgaccaac gcggtaaaca gattgatcgc gataccaagg cataacgtaa
    31441 ctgcaaaccc tttgatcggc ccggtgccga acaaaaacag cgcaaaaccg gtgatcaatg
    31501 tcgtgacgtg cgagtcgaca atggttaaga gggctttatc gtatccggca tcgatggcca
    31561 cccggaccgc tttgccttgc cgcaactcct cacggatgcg ttcgaagatc aagacgttgg
    31621 aatcgacacc cattccgatc gtcaaaataa taccggcgat gccgggcaag gtcagcgtcg
    31681 cattcaacgc agccagagat ccgatcaaac agatgagatt cagcatcaac gcgaaattcg
    31741 cgatgacccc ggacagccgg tagtagatgg ccatgaatac gatgacgaga agccccgcga
    31801 acagagtcgc cttgatgcct ttctcgatcg agtcctgtcc gagcgaagga ccgacggtca
    31861 gatcctgaat gatcttgagc ggcgcaggca gcgcgcccgc ccgaagtacg atcgacaggt
    31921 tgttggcctc ttccatcgag aacgttcccg tgatctgggc tcttcctccg ctgatacgct
    31981 cctgaatgac cggcgccgaa tagatcgtgt tatcgagcac gatcgccata cgcttcttga
    32041 cgttttcgcc cgtgatccga tcgaactccc gtgccccctt tgcatcgaac gtcaccgaca
    32101 catacggctc attgaactgg ccgatggaga cccgggcatc gctgagcaca tcgcctgcca
    32161 gcatgacccg tttcttcacc agataggggg ccagccattc ttgaccactc tccttttcga
    32221 cgatccgctc aaacagaatt tgatcgcctt ccggaacctt tgcttcaacc tgcttcagaa
    32281 aggcctcttc acgttcctta cccttttgga tccggcccgg caaatccagc ttgagttgat
    32341 tgtcgtcatc cagcagtttg aattcgagca gtgcggtctg cttgatgagg tcctttgcca
    32401 atttggcgtc tttgatgcct ggcaactgca cgacgacttg cttcaacccc tgccgctgaa
    32461 tcaacggctc cgccacacca aactggtcga tgcgattccg aatcgtttcc agggcctgat
    32521 tgatggcgga atctttgatg cgcttaatct cggcctcgcg caattcccac acgactttgt
    32581 tcccagagcc cgcgccctcg ttctccacat acgtagggaa ctcatccagg agcttctgta
    32641 cctgggcctt caattcggca ttttgaaatc cgatggtgat ttgcgaagat cccgtccgtt
    32701 tgaccgattc agccggaatt ttcttttcga cgaggagatc ttgcagtccc gccgccgtcc
    32761 gttccaccgc aatctcaaca gcccgatctt cttctacttc caacaccagg tgaatgccgc
    32821 cttgcaagtc caatcccagc gtaatgccct tatccggcaa cacctcgcgg acccaccgcg
    32881 gcaattcctt atagaggggt tggtaggagg gcaagaaaaa gatgatcgaa gcgaccacca
    32941 ttgtcactaa ggctaacaac cgtccgccga cttttttcat acgtgcgcca atccttcccg
    33001 tctccgtcgc gtgcgtcagt cttcttcttc accgcgcagc cgagcaatat gctctttttg
    33061 gattttgatt ttggtcgtat ccgcaatttg gagcgtcacc gtctcttttc ccaggttcgt
    33121 gatggtgccc caaatgcctg aggccgtcac caccttgtca cccttcttca aggtctccag
    33181 catggccttc gcctgcttct ggcgtttttg ttgcggaaga atcagcatga aataaaaaat
    33241 gacaaagatc agcacgaacg ggaccagcga taacaggcct ccccccgctc ccgcgtttcc
    33301 cgacgttccc tgcgcccagg ccaccgaatc ccacatacag ccccctgctt gtcgccttac
    33361 gacatgttcg tattgtctac gtccgaccgc ccttcgccgc ccggccggtc cacaacatag
    33421 gtccggtgaa actcacggcg aaactcctga aaggtgccgc tccgcacggc gtttcggatc
    33481 tcttccatca acttcgcaaa aaaccacaaa ttatgaatcg tattgaggcg ggcgcccaac
    33541 atctctttca cgccgaacaa gtgatggaga taggcgcgcg tatatcgggt acacaccgga
    33601 caccggcagg ccggatcgat gggctgttca tccctcgcat atcgagcctg tttgatcacg
    33661 acacgtccga aggaggtgaa cagccatccg gttcggccat ggcgggacgg gaccacacaa
    33721 tcgaacatat cgatcccgcg cgcgacgcct tccaccaagt cctctggcat gcccacaccc
    33781 atcaaatagc ggggcttggc cgacggcagt tcggggaccg tgacatccaa catggcatac
    33841 atgtcggcct tgtcttcgcc aacggacaag ccgccaaccg catatccgtc aaatcccacc
    33901 gacaccagat cgcgggcaga ctccactcgt aggctctggt ccaatccgcc ttgcacaatc
    33961 ccgaataacg attgatcagt acgacgcttg gcctcgacac agcggcgcgc ccacaaagat
    34021 gtgcgcttgg cggcggcacg cacctggtcg agcgaggagg gcagagcgac gacgtggtcg
    34081 aaggccatga tgatgtccgc gcccaacgct tcctgaatct caatcgacgt ttcggggctg
    34141 atgaatcgtg acgatccatc gatatgagat tgaaagacca cgccctcatc cgtcactttg
    34201 caaaactttg ccaggctaaa gacctggaag ccaccgctgt cggtgagaat ggcgccgggc
    34261 caagccgtga agccatgaac gccgcccaac tcctccacga ctttgtggcc ggggcgcaga
    34321 tagagatgat aggcattgtt caggatcagc ccatacccca tcttcagcag ttcttcaccg
    34381 tcaacactac gtacattgcc cagcgaaccg accggcatga aagcgggcgt cgccacttcg
    34441 ctacgtccgg tggtgagaac cccgacccgc gcccgcccgc ctgcttcttc atgggtaatg
    34501 cgaaacgata gcatccgatt ggcagcctac atctgctctg gggaggaaac acccagcacc
    34561 gtcaacccgt tgcggaccac ctgctgcacc gaccacatga gggccaggcg agcccctgtc
    34621 agcccgggcg acaccgcctc gggcacccga ctggtagaag ccgacggctc ggttggagcc
    34681 gccggagtcg cgtcgaggtc ggtcatcgga ggcaatatcc ggtgtttgtt gtagaaagga
    34741 tgcaccaggc ccgccaactc acgaagatag taggccatcc gatgcggctc cagctcgaca
    34801 gcgctcgctt ccagcaccac cgggaagacc gaaagttttc gtatgatcgc gagttcgtcg
    34861 ggatcgttca gcagtttgag gtcagcctga ctcggaagcg gacactcaat gcctcgtgat
    34921 gccgccacgc gcaacagact gctgatccga gcgtgcgcat actgtacgta atacacgggg
    34981 ttctcctgcg actgctgctt ggccagctct agatcaaaat ctaaatgcgt gctggagtcg
    35041 cgcatgagaa agaaaaattt ggccgcgtcc gccccgactt catccatgac ctcgcggagt
    35101 gtaataaact ctccggctcg cttggacatt tccactttcc ggccgccgcg gagaaggttg
    35161 accatctgca ccagcaccac gcgcaaccgt tccttgggat acccgtaggc ctgcaccacc
    35221 gcttgcatcc gcggaatata tccgtgatgg tcggctcccc agacatcgac caggagatca
    35281 aacccacgcc gcagcttgtc gcggtgatag gcaatgtctg aggccaagta cgtgtaatct
    35341 ccctcctgct tgcgcaccac ccgatctttt tcatccccat aggcagacga gcggaaccat
    35401 tgcgcgccat cctggtcgaa gagaaggtcc cgacttctca gctcgctcaa aacctgctcg
    35461 acggctccag aggacaacaa ggaagcttca ctgaaccagg actcaaacgt aatcccaaag
    35521 gtttccaaat cctgccgtat cagggccaga agttcccgat aggcgaaatc cttgcttcgc
    35581 tgctctgcct cactcgagga aagagagagc agcgttactc cctgctcggc cttcacacgc
    35641 gcagcgacgg cccgaatata ctcaccttga tacccgtctt cgggaaaggg aactgcctgt
    35701 ccgcacgatt cgaggtaccg ggccaggact gacaccccca gcaatttcat ctgacggccc
    35761 gcatcgttga tataatactc gctgacaacc tcatgcccgg ttgccctgag gagacgaacg
    35821 agcgcctgcc ccacggcggc tccacgccca tggccgacat gcaagggacc agtcggattg
    35881 gcgctgacgt attcgaccaa tacgcgccgg ccctgcccca gtcggctgtg accgtactcg
    35941 gcccgctggg tttcaatatg tcgcagaact tccatccaga gatcgggttg gagcgtgaga
    36001 ttaagaaatc caggccgcgc gatatcgacc cgcgagaaca gtgcatctcg atcctgaatg
    36061 tgatccgcga taatttgagc aatttcaaat ggaggccgtc gctcggaagc cgacaaagac
    36121 atggccaccg tgcaggacac atcgccccac tcaggccgct ttggcgcctc gaggttaata
    36181 gtcggcatct gctcgatctt gagaatcccg cgttgttgtg ccgatcgaag cgctcctgcc
    36241 aacgcgtctg ctaccctatc ttgcaccaca ccctgagcca caaaaactcc cctaagtctg
    36301 cgtggaaaca gcgaaaatta atctcgcaat ctaacacacc agaatgtgag agacaagatg
    36361 aggagatcgt cgagaaggac tatgacaacc tgagcaattg actccggcag gcttcaatca
    36421 ggctttccac aggaatgtgc agacacacct tgtcgtggca agtctccacc ttgctccaat
    36481 cagaacaaac gcatggcata ccggaaatga ccgctaccgc gcgcccctgc ggagaccagc
    36541 gagaagcatg agtaggacca aaacacgcta tggtgggaac agctaacgcg gcagcaagat
    36601 gtgtcatgcc cgagtcgtgg ccaagataga gctttgcctg tgccatgact ccggctgcga
    36661 cagacaaact gagctcgcga atgacgggca ccggcacagt cagagatgaa agcacctgcg
    36721 ccacggcccg gcaatcagct ggcccttcca ggagcatggg agccatacgc gcctcgatca
    36781 accactcaat gacctttgca aggcgccacg catccataca cttgttatgg ctaccacttc
    36841 ccggatgaac caggatcaat ggtgacgatc cgtcccagtc atatgcctgc aagacatcct
    36901 ggccctgcct ttccagttcg gcgggcaaca ttagcgatga ggtgaagtct tcccgctgtc
    36961 cctccattcc gactgcttcc caatagcgat ctgcttgatg agttgtcgct aaggccgaag
    37021 aaaacggagt ctgtaactga atctgctgta cccctgcgag gcgcaacgta ttggtcacgg
    37081 caccatcggc atcgctcagc catcccacca ctaactcgca ctgccccaac caagtcctga
    37141 atgaatcact cagcctctcg aagccagcaa acaactggct caggtaattt tcctcaagag
    37201 agaatgctcg atcaagctct gcgctgtggc acaacagaga tcccacagca ttggcggcta
    37261 tcagtgcgat ttcatgttga gggaattgac aacgcaacgc gcgaagaaca ggacgggcta
    37321 acaacacatc gcccaaagcc cctgggtgaa tgaccaacac ccctcgtaga ggcgggcgat
    37381 tataggcacg agcagtcacg ggtgaataga aggggatgcc tcggcagaag ccaactcact
    37441 cggcgtgttg atattctgga acgaacggaa ccctggtccg aatgcctgga gatgattctc
    37501 tgtcaatatc ttcattcgca gggcgttctg gtgaaagagg ttttgaatct tgagttcatt
    37561 tcgttgagcc atcgcctgga gaaacgggac acagcgcttc gaatacaccg catgcattgg
    37621 ctgaaatcga cctcccaaat tagccacgat cacatcggcc gactcatcct gggacagcat
    37681 gaatcggata acttcagggt ctagaaacgg catgtcacac gctaaggcaa ataccctcga
    37741 tcgtgatgcg gtcatcaaac cggtatacag gccacctaag ctacctgcgt ttgggatcag
    37801 gtcatagaca actgggcacc tctgcacatc aagcccctct atcggctccg cgagcactac
    37861 aatgttttcc gcaaaggtaa cccttaagac ggacagcgtt cgttcaaaca cacttgcgcc
    37921 accaaccttc atgaatcgct tgtcttgtcc cattcgccta cttcgaccgc cggcgactaa
    37981 gacacctgaa atatcatcta tcatcggacc cacttctcac atctaatgca acagctaaaa
    38041 aacaacgagg gggtgagttt cctcaccccc tcgccttatg agagctacat taccctttta
    38101 ccgcttacag gaccttgccc ttcttcttgt tggcgcggcg ggtcaacatc caaccctcca
    38161 agaacacgac gccaactgca ataacggccg ggtaaatgta cacttcctga ggaatcggtg
    38221 gctgcagaat cgtgtagtag aatgcagaga ctgccatctt tcgacctgca tcaccattgt
    38281 gtccatccca ggcaaagaat accatcggga tgtacttacc gatatcaaac cgggtgtatt
    38341 cgtcataatc atccttgcta cccttgagcg gacgggagat catgacggtc cactgaccgt
    38401 ttttccactc tgacttcaaa agcttaacct tctcttcgaa gtcatcacgc tcttcaaaat
    38461 cctgatccca tcccgtgccc ttgaaggaac gcagcgaacc gtccgcttcc cacttcaaga
    38521 tgtcggcatt gaatttcgca tcgccgaaca aatagcgtgg tttaaaggga gcaggaattt
    38581 cctgccactt gatggggaac tggaatgcaa taccatcgtt atagacggca tagttattct
    38641 gcgccgctgc gatggaacct tcttcgccgg tctttggagc ctgctctttc acgccgaagt
    38701 tttcgacgtt aacttgggtc ggagcccaag gaagcttgcc ttccgcgatg ctcttcgtcc
    38761 ggtcatccca ctgaatcaag tacaccacgc tcttgtcgtt gtagagtgac ttgacccaga
    38821 tgtcgtcgat acggttcaca aagttgcgtg gcttatgagt gatctgacca cccatggcca
    38881 cataccgacg accctgcttc ttccacattt cattctcagg atcgctagaa atttcgcctt
    38941 ctactggact ggatggaatg acgaagttga tcttcggctt gtcagtcaga ggatcgatac
    39001 ctagaggctt cccttcctca tcgcgttcgc acaaagaatt cacgaagttc gcaatgttcc
    39061 aacgatcttc gatcgacgtg ctgtccgcaa atgacggcat cggggttccg ttgacgccag
    39121 tggagaaggt acggaagatg ttccgaacat tgtacggatc ctgacggctt ccacggaagt
    39181 tccagcactt gtgccaattg gccggctgaa tggagaatcc ccagtcgtct ttgaggttga
    39241 aggcattgcc gtcaccgcgg ccttcgacgc cgtgacattc aatgcacttc ttatccacga
    39301 tcaactgtgc acccttcttg atgctatctt cagtcgcctc ggctggctta atcgtaccga
    39361 gttgaagaat ggtttgggtc tcagactgct tgtccgtaaa cttgcggtcc ttcaccagtt
    39421 gcgtagtcac aaacgacagc acttgaatcc gctgttcttc ggtcaagata ccttcccacg
    39481 gtggcatcgc agagccgggg agaccgtgag taaccgtatc gaacaagtcg tttttgccgg
    39541 agtcaggggt cttttcattg tagttgaaaa gcggtaattc tccactcgcc gtatggcgaa
    39601 ttttgaatgt tccctgattg aagtttctcg gacgcggcca aagccgatct gcacccgggc
    39661 catcgccggc tccatccacg ccatggcacc acacgcactt ggtgaaatac acacgctttc
    39721 ccgcttcaat catatctgcg ggcggggccg gggccaaatc cccctttgcg aaaccctcag
    39781 gaagatctgc cgcttggcca atcccaaccg cgcttgcgga taggagaagg gcaccaagag
    39841 cagccccgat gatcggagat gcttttacgt tcatacgaag tttgctcatt gttaacctca
    39901 ccacctgttc tcccaggttg tttgtaagat tcagaattag tcccatgtcc gaggatagta
    39961 tcccgtgtgc cagtattcga acaagatcac cttccaaatt tcatcagtgg tcaggtgttg
    40021 ttcccatggc ggcatgacgg aggcccaagg gaatccttcg ttcggcaaac caattccgcc
    40081 cttagcgacg cgccagaaaa taaaggtctc ttgcaattgg gcaatcgttc ccgggtcggt
    40141 gaaattcgca ggaatcgggt tgaacgcgaa ggcatgaagt ccacgaccgt tcaaattgtc
    40201 tccgtggcag aagtgacaat tctgaaagaa gatttctcct ccttctcgaa catacttcaa
    40261 gtacccttca gccttgtcat cccatgggtt ggcgttggga gccatcaaac gacccattcc
    40321 ttgttcgacg atcagtttat tgctgtaggc ctggtcgtac ttaccctcga gattgacacg
    40381 gtaagggttc tgcgaggttt gcaaagtata ggtctttcca tgcacttttg tgctagcggg
    40441 aggcgccgga tgcacagtac gcaattcgat cggctcatcc acgctgggct tcatcgtcaa
    40501 gaatgaaaac cctccgatca agataggcaa gagaatcaga tacaacgtgc gaagagcctt
    40561 gtggaatccg gtattggcat ccagcacgtt cagaatgggc tgacgaaact tcttccaatc
    40621 ctcttcattg gcggataccc acataaacac ggcgacaaac gacacaacgc cgtacatggc
    40681 tcggacactg aaagggatcg gtgggtaaat acggaatttg agatacgtct ggacaaatgt
    40741 ccagaacaaa actccctgcc aaaaccgagg aatggccatt cccatggaat tggccagata
    40801 gctcaggccg gtgaagccgg ctacgaacac tgccagctca ctcaatacct gcatgggcat
    40861 gtagccctca acgagcctga cggtgttcga tggaactact ccgaagatca tgccgatcaa
    40921 catgagcagt ccaaggacgc cgatcagggc cccgactgac attaatgctt tcatgtcctc
    40981 atctcccttt cttccgcaat agcgaccaga tacctattcg cttgatttag gaggcctttg
    41041 gaggctcttt tccttcctga atctgcgaaa ggtaatctac aagcttcttg agtgcgccag
    41101 cgctaagctt ttggccaaac accttcggca tcgtgttatc agggaatccc ttgacaacat
    41161 atgcgctggg ctcaacgatt gattccatga tgtagtcagg tacactctta gccttacctt
    41221 tgtaatcctt atccttgatc cggagaggag cattggtacc ttcgaccaac ttaggaccga
    41281 tcgtgccggt cgcccctgca atgccaggaa ttgtatggca ggctacgcat tgacccttgg
    41341 caaaaatttg atcaactggt tcagttccat ctgccatcaa agaagcgcca cctcccccag
    41401 cagccttatc accttctgtc ggcggctttg gtcgatctga ctcaggaatg aacttctcgt
    41461 acgatttcac aatctcatca aagcccggag cctcacgccc ctcacgaacg tacagccagg
    41521 tgtccaccgc tgccaattca gggaggctca acgaaattgg cggcttgtgg atagaaggca
    41581 ttgggctttc tttgtcgttg gtgcccttca cgccgaaacc tgcaacaacg aagcagctcg
    41641 ggcaggcatg cgattcagcg atgtactgga taccattttc tgcggtacca gaaccggcaa
    41701 acgcttcttt ctggttggaa tcgcgagcgg cagggttccc tttgtggtat cgaggatcgt
    41761 tgatctgagt ttcagctcgc tcaggaatgc cgtccaaatt tggcgcacgc tctcccaaca
    41821 tacctttgtg gaatgcgtgg cagagcgggc actgcccctt accgattgcg ccctgcacct
    41881 tattctgccc gacaccaccg aagatgatct tctcaccttc gtcggcaagt tcggtttgcg
    41941 gcatgttgct gaagtccttc ttctcttcaa tcggagggaa tccaccctct acctgaggca
    42001 gccagttccc ataaccggag agtgccgcag cgatgaagaa catgaagccc ccgattttca
    42061 gtaacgcgct gatattcgtg aaatacaggg ccatcatgaa tgtcattgac gtgatcaaca
    42121 ccaacgacac cggcaacagt ctcgattcac cgaagaagtt cattttgtag ttagcaatgg
    42181 ccataaacag gagcaacgcg ccccaaatgc caatgaacgt cttgaagact gcccgcttat
    42241 ttgccaccgg gtccgaaatg gaggccttaa aatagaacat caggccgatt aataggccca
    42301 atgctggcca gcccatcgat aaggctgatt taatgagttc aatcacagct caaacctcct
    42361 gcaggagggg aagcctccgg ttgccatgca accggagacg atccctcatt gattcattgt
    42421 tcgtgttttg attagtgacc aactgctggc gccgcagcac gaccagggac agcagctttc
    42481 gcttctactg gagccttttt cgccgctagg gcacccaacc aaaacacaaa catgatgctg
    42541 atccagaaga acagtacgtt tgcagaaatc atgtttgccg caaaacctac cgtatgagtg
    42601 taggcccatg gggagttgtc ccgcataatt tcattcacgt gccagaaaag cctgaccgag
    42661 gaccggatgt atcccatcag acccatcatc cacgtaaacg cagtagcaag catgataagg
    42721 gcgtactgag atcgcgccga aatcttcccc cattcgatcg gccccatctg cttagcaccc
    42781 ttcatcatga cgctgttgag cgcaaacata aagaagaggc aggacagagt ggttgccacc
    42841 tgaggcacag acagaccgac acgaacgttc gccggaatgt agtagccata aaccgccaac
    42901 atgataatgt tgaggtaggc aaagaagaag aagcagccca tgaagatatt gccaaacttc
    42961 gcccaagata ccgtcgagac cttattgcct cgcatgtacc acacaaagct caaaaccgtg
    43021 gtcgtgatga tcacgttgat gccaccgttc ttggctgaca tgacgccgta gttacccaac
    43081 acagggtgct gctgaccacc catggctttc aactcagctg gagtcatgac gatggtgtgc
    43141 ggggtaataa acacgaggta accgcaagtc aacaagaata ccaagtactt aatgtagcgc
    43201 tgatactttt cagcgccacg catgcgccca agcgcctgcc aaaggtagta attcgtgctc
    43261 aaaaacaaga ttccgatcat ggtcgcctga atgatgaaca accacgcaag caatccaccc
    43321 atcaacgtga tacccatctg ttgacgatag gcatacacct cgcgcatcag ccagtagccc
    43381 gcgaagggaa gaggaatcag gaacgccaca ccaagggcca tggcgatata ccccatccag
    43441 tcgtagtgag cacgttcctc atcagtcttg gccgacaaga aacggtaagc cgcgtaagcg
    43501 gccacgacgc cgcctccaaa cgccatgttg ccgaggatgc ggtgcagatt gagcggattc
    43561 caaagcgcgg tatggatcac gtgccagata tttccgagat accggccctg ctcatcaacg
    43621 ccggccggtg acatcatgaa accgatccag gaattcgcca agaacatcag gatggtacca
    43681 atcacgttca gaacaactga catgctgagg tgaatccact taaggaagcc ctccttcatc
    43741 ttgtcccaac cgtaataata gatgtagaga gtgccgctct ccgccacgaa catcaacgca
    43801 tagatgtgca tgaccggcct aaagataccg gaaaggtact ggaagaaggc cgggtagaga
    43861 gtcaggaagg tgaagatcaa aataccgccc aagatggcgg tcaacgaata agcggtcaaa
    43921 ctgatcttaa taaagtcata ggccaactgg tcataccgct tggccaacgc cttatccttg
    43981 gtcaccacac ccataaactc gatgaccata cagaagatcg gcacggccag aacaaagcta
    44041 ccgtagtaga ggtgctgctg gttagcaaac cagagaagca cccgactctc gaaattatag
    44101 cgcggatagt ccttctcact gtccgtcgtc tttggtgccg gcggcccaga gacaatacct
    44161 tcggtcttgt aatagacatc cttgcccttc tcaacttttg cttcaccacc ctctttttta
    44221 gcgtcggcag ccggagcgcc accatctgcg agagcgggga tcgcaaccag aatgggcatg
    44281 aggaggaggc cgatcatcgc gcatagcgcc atgaccgaca tcaacttcgt gcgggttaca
    44341 gagcccatgg gttacctcct tgatacatcg cgtatgtgaa caacaaagtc aaaagcctta
    44401 tctcctagca cctacttacg aaggagatac caaaagtcca acccttgcgc atccatcaaa
    44461 aagtgatcaa cggcggcaaa aaacgagacg cagatcaaga tcgatacgac gaagtacaca
    44521 attgtttggc ccatcacaaa cccccttcaa cttgataaac attttctaag gccgggatca
    44581 ggatcagcaa ggacactgaa tccctccgaa ccagtaaaaa aaccagaggc tcactgccag
    44641 ggtgatgtag aaaatcattt tgccgatctt aactgagacg tcgtcctgag cagcttccat
    44701 cttgattccc ccaacggttt aagtacgtat tttaaattga cacaccaact atgctgtgtt
    44761 aatcaaaatc cctcacccaa ctgattttta aagggatttt tatggcaaaa aactcaaaag
    44821 tgttcgacat tatagttttg gccggtatgg ttgtcaatat cattttggcc gtgtttctga
    44881 tcctctacta ctttgatttt ctatgatttt cccgtcgttc acgcccccag acaaaggggc
    44941 attacccgcc tttgattgag cgcaccggaa cccaatcgtt tcatctcgaa agtccgccat
    45001 cattttgcta cgagcggtga tacgcaggtc agatcctgaa ctcgtgtatc ccgctcccct
    45061 cagcaccttg taggttccat attcaggact ttcgggattt cgttccgccg ccgcagcata
    45121 cgccccctca aggtaccaat cctctaccca ttccatcacg ttcccggccc catccatcac
    45181 tccataagga ctggcatcac ttcgtactcg tcctaccggg gccgtcacct cgaaaccatc
    45241 gttaatgcgg ccccaattcg caccgcccgg catctccacg tttccccagg gccacaggcg
    45301 accatcggta ccccgcatgg ctttttccca ctctgcttcg gtcggcaacc gccggcctcg
    45361 ccactcgcag taggctttgg catcttccca ggagacatag accgcaggct gattcacccc
    45421 tttcatacgc ccagtatttt tcgcatatcg cgatggaggc cctgacttgc gatggcccgt
    45481 cgccttcaca aaggccgcat actgcgcatt cgtgacctcg tatcgatcga taaagaactc
    45541 gtcaagatag atcttccgtt cgggctgttc atcgaagccc ccctgactcg tccctcggat
    45601 gaacggtccc gcaggaatac ggacgagttc ctcttccaaa ggttgatcgg ggatagagga
    45661 atctgaggcg ctgctctgag aatcctcttc tgagtgctga acctcggact ccaatggagt
    45721 ggaaatcgtt ccacggagaa tggcgatgat aggcaaactg gcggcgaaaa gcaccgcaag
    45781 gagaaacacc actttgaaac gtgtttccag catggtccga ctgattattt cactgccgtg
    45841 tcggcatcca cgtctttcgc gcaacgaaac ccgaccgtga tatcatggcg ccacggtttc
    45901 gcctgaaacc gcttggatgc acggacattc cgtttcgttt ctctccacga accgccacgt
    45961 ataattcgct gctcgccctg atccggtcct ttcggatctc gatatgggga ggcgcggtaa
    46021 aaattttcgt cataggcatc cgccacccat tcaccgacat tgcctgtcat atcgtaaatg
    46081 ccatacgggc tgcgccccga ttcgaatgat cctggagggg ccaaataacg aaatccatct
    46141 tccgctccgt cgatgttggc atagccggaa ataaactcct caccccaggc gtatcggcgc
    46201 ttcccttccc cgcgagcggc cttttcccat tccgcctcag tgggcaatcg cttaccagcc
    46261 catttgcaat aggcctccgc atcatcccac gtcacggcta tggcgggata ttctggcttc
    46321 agcaacttgg caggatcgtc ttcaaacacc tcgatctttc gttttacgcg tcttgtcatc
    46381 ttcagaaacc gatcatagga atcttgtgtc acttcgtgtt tatccagaaa gtaggtcttc
    46441 aaatagactt gatgctcggg tttttcatcc ggatcactgt cattatcacg gctgcccatc
    46501 acaaacgggc cctcagagat ttgcaccatt tctcgcccat catccccgat aaacgtcttg
    46561 tacatagaaa agtcctgcgc caggggcgca gcgacgggct tggcttcggt cgcgatggag
    46621 agggctagct gacgcatttg cttggccttg taggattcat agaccaatcc cccaatcatc
    46681 aaaatgaacg atccgaacac gaaaataatc gacccaatga gtacgcctcg attttccatc
    46741 gccttactcg cacctcataa tttggtcact gcggagtgag ttgcgtctgc ctcactctcc
    46801 tccaactgcg cggcttttct ggccgctcgc acatccagca acatcgaaat ctgtacgcca
    46861 agaaatccgc ccatcgccgc gcccgccccg gccccaaacg aaaccttttc aactccggcg
    46921 atcaaccagg cgagcaagcc tcccaagacg gtgccgacca atatactgac gaggaatctg
    46981 cgtccaccca gatagccaac caccgccccg agagcgagtc caagcccagc ggtcacggga
    47041 atggaggagg caccaagaaa cgagccgatc aaggcgccga ccgtcgccat gaccacaatg
    47101 cccaagacta catcaaacca tgtattggcc gtgggtcggt ccatacgctg cgcgtcctca
    47161 gtcagatgtc cctgttctac ttggccggcc cgaccgtcac cgcgccgaaa tcaatctcca
    47221 cgccggggcc ggcaaataat gaaattcccc aagccttgtc agccggctca tgcttatgaa
    47281 tacgtttgaa atcttcatac acattgaccc gctcttcgac ccactcccct acaggcacca
    47341 ctccactctg cacgaccaat tccgaaccgc tgaacatgcc gccttcgacg aacgtcccca
    47401 ccggcttgcc agcgctccag atgtatttcg taaagacagg aatgaacatc aggtcggtat
    47461 ccaacgaggc atacagcgct gcaaccggct ctgaattact cggcgccttg tgaaggcgcc
    47521 atcgccaagt caggactgga tacaccttcg ggtcccagtc gattttgcgt ttttttattc
    47581 gctgccccgc atctttcgcc gcaagaaact ttttcccctc ttcggactgt aacttgtatg
    47641 cgtcccgccc tttggcctgg ctgcgctgat tttcatgttg ccaatcgaca ggaaacccat
    47701 cctggtctgc agactgaaaa tcttccagca ccatcacgcc tgtctccgct gcagaagcag
    47761 gcgcagctcc tccgagaatc gaacacaatg caataccgct cagcagccct aaggcaccca
    47821 ctaatttcct catacccatt acggcactcc ctgatgaacc ttgtctagcc ttcatgcgaa
    47881 ggagatggca aaaaccccgc ctctttctcc gcgcttacat cttcatgcat caccggctgc
    47941 tgccctcgct gacacaccca aaacaaaaag aacaccgcgc cccaaaagag caccatgttg
    48001 atcgtcacca tcttcgccgc aaaacccaac gtgggagtaa aggcccaagg agacgtgtcc
    48061 ggcatcaatt cgttgacatg ccaggccaat ctgccggagg aacgaatgta ccccatgagt
    48121 cccatcaccc aggtgaatgc cgccgccagg ccgaacaggc caaccatccc tcgcactgag
    48181 atctgccccc actgcaccgg accgtgtatg gttgcgcctt gcagcatgcg ccggttgagc
    48241 aacaatccca gcgtgaccac tagcagcgtt gtgactgctt gaggaccaga caatcccact
    48301 cgaagactcg ccggcagata aaacccatag atcgacaatc cgatgatgtg cgctaccccc
    48361 aggccgaaca gcgcccccag aatgacattt cccaccctgg cccacgaaat ggtcatcgtt
    48421 cgattcgcgc gacggtaata gatgtaactc aacgccgtga tgcagatcat cacgttgacc
    48481 gcgccgtttt tcgaggacat caccccgtaa ttcccgatca ccgggtgttg cgcgccaccc
    48541 atagctttga cttccgtgcc ggtcatcaac aacgtgtgcg gagtcagcca gataaataag
    48601 catcccgtca acgccagcaa cagatattga taatagggct gatagcgctc accgccccga
    48661 atgcgtccca tgctctgcca caggtaataa ttcacgccca gaaagagagc gccgatcaac
    48721 agcgcctgca ccacgaagag ccaggtcagt agcccaccca tcatggtgac gcccatgctc
    48781 tggctgtagg cgtagacaga acgcatcagc caatagcccg cgaagggcat gggtagtaac
    48841 gcgcagaccg tgacaaatag aaacacgtag ccgacccaat cgtagtacgc ccgctcctcc
    48901 tgactcttcc cggaaaaaaa ccggtaacag gcataggcca gcaccaccgc accacccgac
    48961 atgatgtccg cgaggaaccg atgaagattg agcggattcc agagggcaga gcgaagtaag
    49021 tgccatgggt tgccaagata tcgtccctgc ccgtcgacac cagagggcgc catcataaac
    49081 gcagaccagg aattcgccag cagcagtaat gacgtcccgc acaccaccgc gagcaggccg
    49141 atcgaaagat gaacccattt tgttccaggc gctgccattc gttcccagct gtagtagtag
    49201 gcgatggtca ggaaggtggt gccgacaaag accaaggcat acagcggcat catgcccttg
    49261 aaggtgccgc ccatgtactg catgaagctg ggatacagcg tgatgaacat cgtcagcatc
    49321 agactcccga ccgcggcggt gacggagagt gccagcaggg cgaccttcag cagatcctgg
    49381 gccagaccgt cataacgcaa cgccatcgcg ggatttctcg cgactaatcc caaaaactcc
    49441 aagaggacgc aaaagaccgg cagggccaac acgaagccgc cgaagtaggt atgctgttga
    49501 atgataaacc acatcaacaa ccggctatcc attgagccga cctgcggata gtggttgtca
    49561 ttggccgtcg gggcagaagg gccgctggga gtgcctggcg tatggaaata cacatcgttc
    49621 gacgggtccg ccgccatgat agacggagga ctcagcacga tgagactggc cactgacagc
    49681 agcccgccaa ccaagagaag gatcacgaat gaaagcgaac gacgtgtagt catgacgaca
    49741 ctctctggct gctcttctcg aagacagccg cagattcact caaggctgat cccacaatgg
    49801 cttcgcgaga cttgcccaga atgcccatca cgaacgggca acgcagcaag gcgctcggca
    49861 cgccaccggg ctgacgactt tcaatttctc gccgatatcc caagtagtag caatataacg
    49921 gcatgacacc accgacaagg gcggccacgc cggcaaacaa tactatggag ttcatcggct
    49981 gcttcaggac gtagaggcag cccccgacca ataccagata ataagtcgca gcaaaggcca
    50041 atcctggcca ccaccagaat ttcatcaatt caccccagct cgtggcagcc agtctggagg
    50101 tgagggtggc ttggtctcct tggccggcaa aatacgccaa cagaccaacc gtgcctgccg
    50161 ccaaggtaac gagcccgcct tgggccaaca ccgcgaagtc gccactgaca gccatcgccg
    50221 ccagcgcaga aaggaccaca cctccgagga cacctgctgt gacccaggtc aagagcgcct
    50281 gatcgaatcg ttgcagcaaa ttccgtaacg ccacaccatc gggaaaggtg atgaacggtc
    50341 gcccacaggc ctcaagccac cggacatagc cgatttcaaa tgcatcccgc gcgacggccg
    50401 tactgggaat aatgagcgcc atcatagccg gcccatccgg gtgcttggca tagtcgtacc
    50461 ccacaagcca caacagagcc aagaccagca gtgacaactg gattccatac acaaacccga
    50521 tccacccaag aacccatccg atacgctgcc atccatccgc tgtgacaagc tgccgaaatg
    50581 gcactcctcg cccgactcga taggcgcaca gcgccgtcgc catggacacc agcccgcaaa
    50641 gcaccagcaa tgtgagggga tcagcgagag agaagccctg cttggccgcc cgataaaccg
    50701 caaaggccgc taatccgggg acaaacataa cgagacgctt acgtttgcga accgaatctt
    50761 ctgtgacggc cagcgtcaaa ctcggaagca cgcgtagagc caaccgatgc aacatagtgt
    50821 catccacccg aatcaagaga gccagtcacg ggagggacac ctggtgacct cctgcacacc
    50881 gtctcaacac ctactactac gctcgctgtg cggccatgcc gaaatatcgc gccttgacct
    50941 cttccatcaa cgcgacactg accgaacgct cgccccgatc cacagccgtc cgctcgagtt
    51001 caatacgcgc catggcacgc acgggcgccg gcacgttggc aagccgctgc tcggcatccg
    51061 catcccaggc gacgacatcg ccggtcagtg cctgatcgat caactcgtac gtgatgaccc
    51121 ggtgccgcct ggatctggca aacccttcga ccaactcacg gagcgccggc gccgcatagg
    51181 ggggaacacg atccaggcga tgcttggcat cgtccgacca catcaagcga tcaacgagtc
    51241 catccacctg cccagcgggc atatcgattc cgaccagcca tcggcaggga cgacattccg
    51301 tgcggacgaa ccaggtcgcg tcgcccccat gcgaccgccg ttcctcgata ccctcggtgt
    51361 gcatccaccc gccgcatccg cacacaagca taagacgtcc agcctctcag ccgttcccga
    51421 tcgctaaccg attttgccag ggtacaaaat atacaacatg gcgtacgtaa acgttcctgt
    51481 caggaacaag atgcagtaaa caatcatcgt aaaccggccc agcgcccggt gacgctgacc
    51541 gccatcaggc cagatccgct gaatgcccat ttccaccgca aacacaatcg ccaccaggct
    51601 gagaaatccg agatagacct ccagcttgcg catggaaaat ccggccgaca tcacccgcgt
    51661 cccgaagagg acgatcacca cggtcagcag aactccgaag atcagtccga ctttcttcca
    51721 ggaggtttgt agcaacgacg ggctcagtac acggcttcca ccgatgaatt gctgagatcg
    51781 aaaccccaac acaatcatgt agacggccat gaccagcccg ataatgacga gaatgatgtg
    51841 aatggtgagc accgggatga aaacatagtc gtacaacgct tgcgacccgc cgaagccttc
    51901 cttcccttcg aacgccaaca ctcctaattg ccgaaacaga taataggcgg taaagaaccc
    51961 caccatcgtg atcatgccgc ccagcatcaa ccaatgatgc ggatgtccgc gatgttgctt
    52021 cgcctgaatc cacccgatga tgaagaggcc ggtaaacagc gtcgccatca attggctgag
    52081 atcggccccc atcgtggcgt gggttccgaa gaaccccggc tgtcgaagga attcaaacat
    52141 cgtcaactct ggccggcact tggcttcaca ccctgcacca ccgccgtccg ttcaatctcc
    52201 tcaaccgaaa catagccgcc gtcatgcatc cattgcatgg cctcagccgt gcgataacag
    52261 gcgccctgtt ccgtattgac gagaatgtga acagcaaagg cagccgtcca ggccgggctg
    52321 gtgccggacg catcgaggaa ccgatccttg atgatcaggc gcccaccggg attcagatgg
    52381 ctgtgaatct tcttcaccaa cgccgcattt atcgcaaggt cttggtaatg gagaatgtcc
    52441 gacatcaaca cgacatcata agggccgccg agggcatcgc gattgaagtc accggccttc
    52501 aacgcaattc gcccctctag acctgcatct ttgatcgtcc gttcagtcac ggggagagtc
    52561 gtggcgagat cgaataccgt cgctgagagg ctcggataca cctgacaaaa ggcgatggca
    52621 ttggtgcccg cgccaccacc gagatccagc atagtcttcg cctgccccag cgcgagtcgc
    52681 ttcgccaggt ccggcccact ttgctggccg atccggtgca ggacagacag gacattggcg
    52741 ccaagcgccg gatccgtctc aaacacatgt tgcgtgaccg gggatcggcc tgttttgata
    52801 gcctcttcca acttgcccca attcccccat tccgcatcgt gaaggaggag caaatggccg
    52861 atatattgag gtccgtgctt aacgagatgg gtcgtggcca cagaagtatt agcatacacg
    52921 gctccggttt tcgtcaacaa ccggatggcc accaaggcgt tgagcagcaa ctccagggca
    52981 cgagaatcag caccgagttt ttgagccact tctgcggcgg aacgcccctg accgtcgagc
    53041 agggaaaata catctaactt tacggcagtt aaaaggattt tggtctccca gtaatagccc
    53101 aactggaaga cttcggcgag agacaattcg cgaggcacag atcccccact tagtgattga
    53161 ggcaattgaa gttggtcatc ttaccgagtt cagaaaggga aacgcaaggc gaggagcggg
    53221 caggaacgag tctgacaatc gactaatctt gctggttgca tcgcaacaaa ctgagaacga
    53281 cgcatcgtcg aaattgcgct gactatctct actttactga ggagtcgtac gattcaagac
    53341 aaacaaaaag ggcagtggtt caattcgaac cactgccctt tcctcagcag gttatcccgc
    53401 taaagtaaaa ccgactactt gatttcagcc ttcaagttcg ccgtgccgcc ttcggccact
    53461 tcgatctcga attcattcag cttgcccttg ccaacgaacg gatgccaaac aaccactttg
    53521 tgcttgccgg caggcacgcc cgggatctcg aacgagccat catccttcac caccgcgtgg
    53581 tacggattcc acaccggcaa gaagaaggac tgcatgaact catgctggtc gcactgcaac
    53641 cgatagtagc cagccttttc ggcgccgcca cggaaagtca ccggcttctc caacttgtca
    53701 cccttcttgg ccaaaccgat gttgaatccg gtggccgagg tggagccctt caccgtgaag
    53761 ctgtgcgggt tgtgcaacac accctggaca gacttgggat catcaggatc agcgtccttg
    53821 ttctcagcgc ggaaattctt gttgttcacc acgacgccgc tgaaggggag gaattcgcag
    53881 aattccgcca cgacgtccgt gcccttgaaa ccatcctgga aagcctgatc ttcgatatcg
    53941 accacggcca caaccgcacc cttcagaccg ccgtccttgg cgacttcaat ggtcttgagg
    54001 aagcgcttat cgccatccat gaggctcttg ttcgggttct tggggcaaaa cttcgggttc
    54061 gggaacttcg cgaaggagaa ctctttctgc tctgccttcc cgggataggt cactttcccg
    54121 gcgatcgtac caccggcaaa cgcggtgagg ggcgcagcca aaaatgccgc ggccgcaacg
    54181 ccgaatactg ctttcatcgc acccttcttc atgtcactgc ctccttgtaa tgaacattaa
    54241 ccggccaact acttcgtcac cactcaacca caagggctgg tgaccaatgc cccttgttgg
    54301 atcgttctcc gctcatgacg cagccgtgga aggactgcgt ttaggcctct gaacatttct
    54361 ctatactgga atcccactcg cactgtcaac ttgaaatccc tgcggcctga cctctcatga
    54421 tttcgcttga ttagacggga atttcgcatg gccaatgatc cgcgcgatcg atccgccgac
    54481 cgttgctcgg acggcatcat cttcatcatg caatgccgct ttcaatattg gcaggacctc
    54541 tgcccctccg atttgcccga gggctcgagc tgcggcgata cgcggtcgtg gaatggaatc
    54601 tttcagcaac ccggcaagga actcgatcgc aggttgcgta ttggcgccat gcgcccggcc
    54661 cgccgctttc cctgctgccg aacgcgttcc cgggtcgttg ttttgcgcca actcgtacag
    54721 tgcttcggcg actgactcaa agggctcctc tactcgcaac agagccgaga cgacggccgc
    54781 cttaaccacg gggttcggat cagccagaga ctttcgtaac gccaccagcg actctttcac
    54841 gcctaattca cccaaactga tcgccgctga ggttttgact gccggtatct tatcatcaag
    54901 tgccttctcc aaagcgggaa tgccctgcac cttgcccagc tctcccaatg ccgacgccgc
    54961 cgcgccccgc acggaaggct gggtattggt catcgcctcc aggagaatcg acagcccccg
    55021 cgcatctttc aaatccccca ccattctgag ggccgtggca cgctcttccg ggtttggagc
    55081 cgccgctgcc ttctgaatcg tttcccacat cgcagtctgg ccggtatggt aaagggcccc
    55141 tgcggccgcg aggcgcacag ccggttgttc gtctttgagg gctttttcaa gcagcggaat
    55201 cacggaacgg tcaccgcttt tccccaacac tttgatgacc gtggccttca ccaatccggc
    55261 ttgatcctct aacgcattgc gcaagcgcgg cgacttccgc cccgcgtcca gcttccccaa
    55321 agcctcggcg gccagggcac gcaccaaacc ggacccatca ctcaatccgt cctccagcgc
    55381 cgggatcgtt tcggccgaat cgacatcttt caacgccgta tacgccgcgc ctcgcatttg
    55441 ctctcgcata tctttgacga gtgcatagat gaacccgagc gacacatctt ttaaaagcgg
    55501 ccgatcctcc tgctttgact cctgctcgtg ccgttcatac tcgaccaggg catccttcgg
    55561 tttcccaaga aaaatcagcg accgaacttt cagccggcgc gtctccggct ggctgccttt
    55621 ctctttcgtg acttgctcaa tgatgtcgag ggcttcctga tattgcttct tgtcgaaggc
    55681 agcttgcgcg tcctttaacg aaccagcatt ggcaggaacc ggccagaggc cgaccagcgg
    55741 cccggacacg atgacggcgg ccaagcacag gttgacggtc cgaatccaac gcctcttagt
    55801 ctgcaatccc atgaaatccc ttcctgctcg tgccactcac gttcatcctc gctcttgcgc
    55861 attcggtttc ggaacccagc gttggtaccc ggtaggctct tcgaaataat agtccggttg
    55921 aggagaaagc cgaaagcgga gatattcgat cgaccaatca cgatcctggc tcaccaattt
    55981 caacacgatg cccgtctcca catcgaccca ttcatagaac cgttcattcc ggccgttata
    56041 atccacccga acttcgtaca gcctggaggc tcgcccgatg gtggtggcat cgccgatcaa
    56101 cgtccggcgt tgttctcccg gtagggtggg ctgaatcggc aggatttctt caggtttgat
    56161 agggagcgag aggatttgcc ggcgctgggc cagcagaaac cacgactcgc gtttatccaa
    56221 acgaagaatt tctatactgg aataacccag ttcggtcttg atcgcatatt tgtactccaa
    56281 ccgaatgcga tcactcttgg caaacacctg ggcttcgaac cgacgaccct ccacccgctt
    56341 tacgagcgat gccgagaatt caacggactg tgtgaccgac ggtacgctag aggaatcttc
    56401 accccaagca ggcacgatcg acagaagaca gaggctgatg gagaggcacc ctctcgaaag
    56461 ccatggcacg atgccggccc ggccgcgatt agtgctgatg ctccaccaac ggttgaatct
    56521 ccacgggatg cccaagggat tcaagcccaa atcgcggatt ctccattgcg cggtacgccg
    56581 tgcggacgcc ctttggtgcg ggaagcgcta ccttttcagt cgtcgtgcca tcgggagcga
    56641 tcgtgatcgt ccgcgtcacc ccaggacctg actgcggatg ccacacgacc atttgataga
    56701 ttcccggcgg cacattctca atcttgaagg ccccctggtc gtctgtgact gcatagtagg
    56761 gattattgac ggccatggcc cagctttcca tataggcgtg aaacccgcac tgcatgtaaa
    56821 acgttcgtcg ccccttgttt aaatagaccg gccccaccaa ggacttgcca ggagcatgat
    56881 tgtgcacggc gcgcatattc ccgcgctgat gctgatgatt gagaatcaac ggcgtattga
    56941 acaagacccg cgctccagcc tccggcgagg tttcatagcc ctggatgtca tgcatgacgg
    57001 gatccatatt cacgacttcc accgcgtgcc cgttccggac gatcgtgacc catggttgga
    57061 acatgcaatc gcgtgcttcg atcaagggga cggacatgtc gaatgctttc cccgattcca
    57121 ctccttccag cgtgacaatg gcgttcttca gtcctccctc gggggagaca ataaaatcgc
    57181 gcagcaaacg ccatccactt ccgttagaaa tccgcccaca gtacgtcggg tccggaaagg
    57241 tgatgagatt gaaggctttg gggtctggaa tcccgccaga cagcgtcact gtcccatcga
    57301 cggtaccgcc gtgttgcaca tcaatcacct cataggcccc caccggcgac acggccaccc
    57361 ccagccacac caacacagcc gctgcgaagg aatgaatcct ctgagttcga ttcagcatca
    57421 tgaccttcct tgtctgcaat tcgcgctgct acggaacctg cctttctaac gtcgggcgaa
    57481 tatccacgac cttgccaagg gattccggtc cataatgggg attatgctcg atctcgtgga
    57541 cgctgcgccg gcctttcggg gcctcgaacg cgaaatcgac cgtggacgtt cccttctccg
    57601 tcaccgtcac cttcttctgc agcatcgttc ccaaggccgg atgccaggcc atcagcgtgt
    57661 attcgcccgg aggcacatca ccgagggtga acgtgccgcc atcagtcgtc agcgcgtaat
    57721 aggggttgtc gacggccagg ccccaacttt ccatgtaggc gtggaatccg cactgcatca
    57781 cgaaaatccg ccgtcccttg gtcatgtgaa tggcttcttt caccggctcg cccgccagat
    57841 gctcatggct ttccgcggtg acaaagcgct tgtgatgggg attcatgggc agaggcgtat
    57901 taaacagcac acgcggcccg agctgagacg tctcataggc ctgaatgtca tgcatgaccg
    57961 ggtccatgtt catgaccgtc acctcggagc catctttgac gaccgtgaca aacgggagaa
    58021 accggcagtc acgcgcctca atcgtcagcg gttcgaattt gaacggcttg cccttggtgg
    58081 catcagtcaa gaggaccacc acgtccttca aaccgcttcc ggatgtcatt gagaactcat
    58141 cgagaattct ccagcccgtt ccggtcgaga tacggccgca gtacacggga tccggaaagg
    58201 taatgaggtt atatcctttc ggggtcggtt tccccccgat catggtcacc gtgcccgtga
    58261 tattgccacc gtccgtgacg gttatttctt cgtaagccca tgattgagaa gagaaactgc
    58321 tgagagcagc aagcaaagca attccggccg ttcgcatgta tcaatcctcc aacgatgatg
    58381 ggttggtcag aaagtctcag tcgaaatgat ctcggacact gagctgatca tacacaatcc
    58441 ccatctcata acaaaagggg ggagcccttt caggctcccc cctttctcac ctcgcgtgag
    58501 attgacctgc ttacttcgac gcgacaggca tcgcgtgcgc agcaggctgc tcgacttcgg
    58561 cactcttggc tcccgcaccg gcgccggtca aaggcaacag tctggtatcg cctgctggca
    58621 acacccgcac atagccccac tgaccggact gcgagtatgg caaccgctgg ttgctataca
    58681 catagtcgcc gggcatccga tacattccac ccgctgaggg caggaaggca tcgatcgtct
    58741 cggaaccgga gaattccacg acactgatca ggtcagcgcc acgcatgaac ggctcgatcg
    58801 gccattcgtg cttctccacg ctgaacatgc cgttttgctc attgctgaca cccagcacat
    58861 ggatacgcac cggatctccc gcatgcgcct cgatgagtgg ggtggccgga tcttccggct
    58921 tatccgcctt gcaaggctgg aagaccttgc ccagcgaaca accctgctct tcacggaact
    58981 tgtatggttc cgaccggtaa ttgacgccgg tcaaacccgc cacgttctgc acatagggca
    59041 tgaagctcgt gccgatgatg ttgtcttcgt cctggaagaa caacgccacg tcacgataat
    59101 tcgcccgcag ttcattgccc ggcaccgaat ggtcgatgat gacatcggct gcccaggcat
    59161 tcttgttcga cagatccgcg ccggtcttgg gatcacgata cttggatccc ttgggaccga
    59221 cgacgacggc accgaacaat ccgttgcgcg gattggtcat cacattgccc caatcccaca
    59281 ccagcgaggt ggtttcgccg ttaaacggat ccgcgtaata cgtgtagtca cgctcgcctc
    59341 ccggagccac ggtctggtct cccggattgt tccctacgtt cgcacccatg gaatccttcg
    59401 gatcgaaggc caggccgatt gcagagaagg aggctttgct gtccttcatc ttgttcttca
    59461 aatgcacctt gacgcagtca ccgctgttca cgcgaagcgt cagcggcatc ggatgcgcgc
    59521 cggcggcgac cttggcagtg tcctcttcca atgcgtagat cttggcttcc gcattggtca
    59581 tgaggatccg tcgttcaaag tccacttcga tggattccgg tgccttggca ttgaacttca
    59641 tgccggcata gtccatcgcc accacattga actgcttcac aggagcgtca gccggacaga
    59701 ccggcaaggt cttcggaatg tcgcccttga tggagaagcc cgcgggcagc ttcttcaaat
    59761 cagcctgctc tttatccaag acccggatga tgccccagcc accctcggag aacttcgagg
    59821 accggccgtt gaagtgaagg taatcaccgg cttgatgccg agatccacct gcttccggca
    59881 ccacaaggtc ataccgctcc gcgataccga tatgaatcga attcttccgg ttcgcatccg
    59941 cggcataccg ctcggtccag aacgtgtggc cggacagggt ccagaccatc gactcgttca
    60001 tgagggtatg caacagacgg aacaccatcg tgtcacccac ataggcgcgc aaggtgggcg
    60061 tgtacggatc gccgtgcacc tggctgctga agatctgtga cgcatccgga ttggtcgcca
    60121 atcgctgcgc gatcggcgcc gcccggaagt tcaatccgct gccagtggtg tgcgtgccac
    60181 cattcaggaa cggcatcggc gtcatgtaga tcttctcggg catcatgaag gacacggtct
    60241 ttcctgcctc gagcgccact tcaatcggct gcccgggagg attgcccgcc gtcacgacgt
    60301 tgacggtgtg cggcacggtg tcgtgcactt gcaccatcaa ctcacggaag ctgttgttca
    60361 cgccgtgacc aaccggctca ttcgtgtgaa tgtccgcgat cggtccgcta cgaatcaact
    60421 ttccagtctt tggatcatga taggtggatc caaccggctc ggcgatgaag gtgccgaagc
    60481 cgccgtgcgg ccaagtggtc gcaccgaacg cgtggtcgtg ccagaacacg gtccccacgt
    60541 ccgcatcgac ccagaaccgc tgacgcacga actcgaccgt gacgatgtca ttggccgggt
    60601 gatcgttctt caaccccttg gccagggtga tcgtattgcc gttgatggcc ttgatgcggg
    60661 agatttcatt ccccttcaca ttgtcggcac ccacgagcag caatgtcccg acatggaact
    60721 gctttgcatt cttgactgtg atcgtgttcg cgcccttctt cgcggcggcg gtcacgaccg
    60781 tgttcatcgg aacaggcaac cccttcgcat tcttcttttc cagcatcgtg aacggacgca
    60841 ccgactgttc gtatgagaag ccggtgatca cgccgtctga cgcctggttg tcgaattgca
    60901 ggaagtgcca gtgggtgttg atcttcgacg actggaagtt cgtgtagtcg tcgtcgtccc
    60961 actcgctggt caaggtccaa tccacgcaat catagatgtt gccgcggacg accagcggat
    61021 acttcaaatc atcgttctta cgaatttcag cttcttcttc atgcaagacg tagatcaagc
    61081 cgttcggatc gatgaccggc ggctctttcc ccgtcttctt agcaatggtg atgggcagct
    61141 tgatgaagtg gacattgtag tgcttccgac cggcattctc cggacagagg ctccagttgc
    61201 cgttctcacc aggcaacgcc tgatcgacac tctcctcacc gttggcgtca cggcggatca
    61261 tctccaacca gggcgcgccc acgtgattcg gggagaacat gacccgtcgc ccgaaatgcg
    61321 gcgtgaggtg aggccatgcc actttaccgg tcagcggctc gaacgtgatc gggtgccgct
    61381 tgcccggatg ggtggactta tacttcggat tatcaatggt gctctccggt tcgctcaatg
    61441 cacgggtgcc ttcccaggcc caatccaaca ccgtggcatc gtaggaaacg gtctggccct
    61501 tttcgtcgtt cttgtgtccc ggcttgccca tcgtcgggag ctgcatctca acccagtcct
    61561 tgatcgtgac gacggctgga ttggacttcc aatcgctctt gcccttctcg acgatcttga
    61621 aggacttgcc gaaccaatcc acggtctgcc cgactaactt gtctgaggtg atcggacccc
    61681 tgatgcggcc ctttcgatca ggcaactcgc gcagatcagg catgacgtca ttacgcatgt
    61741 caccctgttg cagcgtgttg tacacccgcc agtatcccca catgcccgcc acataatggt
    61801 gggccacatg gcaatggaac aggaagtcac cggccaactg ctggcacaag cccgagccgc
    61861 actctgtctc gaggtccaag gcttctgacg gcccgatgac ttcgacgtcg acgcggtccg
    61921 tcttggcacg gatcaccgga tatttaaccg gtccgtttcc ggcggtcgtc cacaaattca
    61981 tgtcatcgat ggcgcgcggg ctgcgcggcc agcggatggt gccgccatgc ggatggtggc
    62041 tatggaacac ttccgatcca ccatggacga ggcggaactt cgccggatcg cccatgtagg
    62101 aacgaggaat cgtaggcgat ggatcaccga aggtgtacga gctatatccc atcgactcgt
    62161 cttcgaagcc gaagtactcg tgctgcacgt gcatgttatt gatgccgaag ggctcgctgc
    62221 gatagttgat cgcgcggcca cccggacggt aggcatccgt caacgggtca cgctgaggga
    62281 ggaagtcgcc cttcttattg acggggcgga aggcctcgtc accgacttcg tggtagtaca
    62341 acacgaactc gcggaaatcc ggaccggtgc cgttccggat gatgacctgc cacccgctcg
    62401 cggtcggggt cgcatcgccg gtacccaagg cttccaggta ctcagatcca cggggttcga
    62461 ccacgaacga cccgaagaga cccatcacgg tcaattctcg gtcattggcg aacgtatgga
    62521 actgccggac accttcctgc gtgctcgggt gaatgtacca ctcgaactcg ccgctcttgt
    62581 ccttctggac gatgctgtcg gagttcgtcg tggcggccgc cgcaccggtg gcgcttacca
    62641 ccatgctgga gccatggata tgaaggctga cgtcttcgcc accctctaac ttgttggtca
    62701 gcttaatctt gacgcagtca ccctggttgc cgcgaatcgt cagcggctga atccactggg
    62761 cctgtacgcc gggaatcacc gccccaggat caaacccttc cttgtcgcgg gcttcccgat
    62821 tcttcgtctc ctccgcccgg accttgtcga ggttttcatc cagcgtgtac atgtagccgg
    62881 gataaaaatc gagccactgg ttgagtgtga tctcgacgtt gatcgccgac acattatatt
    62941 gccggaccgg cgcagtggcg gggcacttcc cgccattcgt cattgccact ggctccactc
    63001 gcgggtcaga catcaggaga aggtcctgac cgcccgcccc atattggtgc atcatggtct
    63061 gggtattgaa catacccgta ttgaccgctt gcgcctgcgg atcattggtc aaatgctcca
    63121 tgacccgctg gtgctgctgc tcgaccatcg cagaccgctc cggctttcca gccatggcgt
    63181 cttcgacgat cgtttgccct ttcaacttct ccgcccacga cgggagttga tgggacattg
    63241 ctgtttgttg aggcaccgca tgatccgcgt gcagctgact ttcagccgac gcggctagcg
    63301 gcaggcacac aagcgcgccg ccagcaatga cgctgagggc gcgcgatgtg acgcgagtga
    63361 accactgaca atccatggac cggcctcctt ggatagagtt tggatagaaa ctgatgtaaa
    63421 tgttgagcgc ttacgaacta gaacatgaca acctcgataa aaagcgactc gttctggttg
    63481 taatcctgcg gtttcacgcc cgcagggcac tcccctgaga caagggccgg agattactga
    63541 actcacccgt ctctgtcaac ccccttgccc ccgtcgcgag ggtgagtgtc acctacgccc
    63601 tcagtgattc acactccttc tccgtatcag tctggcacca tgagacatcg gaaggcgaca
    63661 attgaacttc ggtcgatgac tcagcgggaa tcgtcacgct ccattgtctc ttttccgcca
    63721 gttgaggcat aatgtcgcat gatcttgaaa cgctggcttg ttggcctgcc actcaagacg
    63781 aaggaagccg ctcacgaacg cctttctaag cgactcgccc tagccgtctt ttcctctgat
    63841 gccttatctt cagtggccta cgccacggaa gagattctgc tcgtcctcac cctggccggg
    63901 acggccatgg tcggctattc catcccgctc agcctttcga ttatcggtct gctggtaatt
    63961 ctgaccatgt cgtaccgcca gatcatcttt gaatatccgg agggtggcgg cgcctacatc
    64021 gtcggcaagt ccaaccttgg agaatggccc ggcctcgttg cggccggcgc gctcatgatt
    64081 gactatgtgt tgacggtcgc agtcagcgtc gcggccggca tcgcggcgct cacgtctgcc
    64141 ttccccgacc tgctcgcgca tagggaggcc ctctgcgtgg cggcgatcct cctggtcacc
    64201 gtcgtcaatc tgcgcggcgt ccgtgagtcc ggacagtttt ttgccgtccc aacttatatt
    64261 tttatcggca cactcacagc catgctcggc gtgggcgcta ttcaaatcct gctcggccac
    64321 gcgaccagga tcgaaccgct gccaagcctg actccggccg aaccattgac gctgtttctc
    64381 ctcctgcgcg ccttttcgtc cggctgtacg gcgctgaccg gcgttgaagt gatttcgaac
    64441 ggcgtctccg cgtttaagaa accggaggcc aaaaacgccg ccttcaccat gatcggtatg
    64501 gccgtgattc tcggaaccct gttcatcggc atcagcgcca tggcctacta cttcggcatt
    64561 gtgccgaaaa gcgacgagac cgtcgtctct cagatcgcgc gcgccacttt cggaaccggc
    64621 ctgctatatt tcctcgtcca ggcctcaacc atgaccattt tgatcctggc tgccaacagc
    64681 agcttcaacg gatttccccg tctggcctcg attctcgctc gtgacagcta catgccgcat
    64741 caaatgtcca tgatgggcga tcggctcgtg ttctccaacg gcgtgatcat tcttggcgtg
    64801 ttttcctgcc tgctgatcat tctcttcaac ggcgacaccc atgctctcat tccgctgtac
    64861 gccgtcggcg tgttcctgtc cttcacgatc tcacaggccg ggatggtcaa acgctggctc
    64921 gtcaagaagg gaccgcactg ggaaaagaag ctgctggtca atggtatcgg tgccgtcacg
    64981 accgccattg caaccgtgat cattgccagc accaagttcg cccatggcgc atggatcgtc
    65041 atcgtgctga tcccgatgtt gatcatgttt ttcaaggcca ttcgctccca ctataaagcc
    65101 gtttcggaac aggtggctct atcccgaggc caccgccccc ctctgccccg gcgcaatatc
    65161 gtggtgctcc cgatcggtgg cgtcaatcgc gccgtcatcc gcgcagtaga ctatgcgcga
    65221 agccggtccg gagatattcg ggctgtcctg gtggatgtcg atcctgaaga aaccgcgcgg
    65281 gtggaaatcc aatgggccca gtggggttgc ggtgttcccc tcacggtgct gccgtccccc
    65341 tatcggtccg tcctgagttc cctattggat tacctcgaac aagtactgca aaaggaccag
    65401 gaatgctggg tgaccgtcgt gatcccggaa attcttcctg cccggtggtg gcaaaatatc
    65461 ctgcacaatc agcgggcctt catgctcaaa ggggccctct tgtttaaaga tcgcgtgatc
    65521 ctgactgatg tgccttatca cctgacgagg tgagcatgcg aaatccacga gccacaatcc
    65581 atcgtacaaa ccggcgagta ggcgcccacc tggtcgccat ggtcctcctg ctgggactct
    65641 ctccccatcc ggggttggcc ttcacgatcg tcgctcctaa aaacggcaca acgttgacgt
    65701 ccggcgagcc aaccaccgcc gaagtcgaag cagggcggga ggcgggcctc gtcgaagtgc
    65761 gctactactg gtatccggag cagacggaat ctctcgtgga gcaaggcgac gagcggtctg
    65821 gaaaaggctc ccagggcagc atctcaacag aaaagtactg gcagaaagac agcatcacag
    65881 gagcgcccgt ggtcgcgctg ccggcgctga cttcaacggt ggaccgggtg ccgccctatg
    65941 gtggcgcatt gcctgttccg cctgacgccg tcggccggat gcggctcctg gccatcgcgg
    66001 atatttcaca aggccgcctg ggacgcaaaa ccgtcttcga tgaagtcttc gtcaccgttc
    66061 agccaaaggc cgagcttctc tcgatcgatt ttgaaacgga aaaaccgctc caacttggtc
    66121 gaacaggaca gtcctccgcc tatggccatg tcgattcact gggcaagatc ttcgaactcc
    66181 cggtggtagg cgaatttgca gacggcatca gccgcccgct gtcctctccc agcgccggca
    66241 ccgtctatac atccgggaac gatcagatcc tcaaggtcct gcccgatgga ttgttgcaga
    66301 ttgtcggcat cggcaagacc tcgctcaccg tcaccaatcg cggcaagcag gccacactcg
    66361 acgtacgcgt ggaggtcaat ccggagccga atgaaccacc cgttgccaat gccgggaccg
    66421 ccaaaacagt gaaggccggc acgaaggtgc gcttaagcgg attgcaaagt cgcgacccgg
    66481 agggagaagc gctgttttat gcgtgggcac aggtgcgcgg gagtaaagtg gccatgctgg
    66541 acgtgaatat ggcggaaccg tcgtttaccg ccccgtacgt gtcggaaacc cgcacttttc
    66601 gtttcaaact ccgcgtgacg gataagaaag gcgcggatag cgtgccggcc tatgtcgacg
    66661 tgactgtcga accctaacgg ctgctgaaaa aatgatcccc gacttcgttc ccggctcgaa
    66721 ccgatcgtca acgtagccaa aggcgacgcc tccggttgct tcctgcctgc ggcctcgggg
    66781 gatgatgttt ctctgtatct gcggggatac gctcgtatct tctccgatac agaccttgca
    66841 gccttccaac ccctccatca taaagaccgc atacagtgcg ctgcatgtct gccggaacgg
    66901 aagtgacgtt cgcgcgatgc ccttgtgcta gtatcaccct catctagttg aataccgtct
    66961 cctaccgcca accatggagg gttcctcatg gcactcattc aacaggacct cgttgcaggc
    67021 agcgaggatc ggctgctcac gctggatacc gagacgaatc tacagtggct gaatctttcg
    67081 cagaccgccg ggcgatcgta tcaagagatt atgaacggat tcggccagtt cacgacggcg
    67141 cacgggtttc actatgccga cggtcgtcag atcggcgagt tatgcgggca tgccggcatt
    67201 acgaaaggct tgacggaacc agccctcacg ccttccccta atgatgcccg gaatcaccag
    67261 gcgatccaga ccctccaaaa ccttatggac ggcaaagtgt ttcatgccga gaccaacgtg
    67321 atcaccagcc gcggcatcat gaaacctccg gctccgccac cgaacgtccc gacgagaatt
    67381 ctgggaacca ttcgactgtc tctcagcctc ttgaatatca cgggctccca tgcggaaagc
    67441 gaaggaccga ccgcaagccc gcagaccggc gatccggaaa tcggttctta tctggttcgg
    67501 aatcagccgg aggcgtgagc gcaccaacaa cgggagacgt gtggtctgac aacaagacgg
    67561 cacgacgcga ttcatgcgca cagtacacgg gccccggcgt gaactgacgc cggggcccgt
    67621 tctgcagcca cctcactccc gagtccatga ggggattaca tcaggctcaa cgtctctcgc
    67681 gcctgagcca attcgattcg atgacggcgc agcgcgggac caaacgcgga tgcactgacg
    67741 cgttgctcgt actcctggat tcctcgttcc atagaggtaa gcgcatcgcg taattgcgtt
    67801 accagtcgct tgccgcccct tgtaagccac ttcagatgct tgcccgcata ctcgagatcc
    67861 tgcagcgaat aacggactga ttcgatttct tccaggcaac ggtaccgagc acgggcgagg
    67921 tcgcgttggg tgaggcccgc cttcgtccag ccggcttttc ctgacgtacc tgatccccat
    67981 accacgagcc gctcgaacag catggcgccc atcgtaaagg tgaaggtcgc atgcaggatt
    68041 ccgcgcaacg ggcgcagtgt gcgccgccag ggcgaataga aaacttcctg attgtgatcg
    68101 tgctgataca tcacatcgtt gcgcagcagc agattgaggt gatgatgact attctcgtgg
    68161 atcaaatcat cgatcaggtc cagttgatcg cgctcaaagc aattgatggc ggagaacccc
    68221 ggacgatgcc ggtaactgaa gctgacgaca cccgcggctt tcaacggcac gatgcgcgag
    68281 gtcagcaacg ccagcaaccg gtctccttcc ggccaggccg cggcaatggc cgataacgcc
    68341 cggcgcatgc gcacggcgac ttcctgtttg gtcggtcgca caccgatcgg cgtcttgtct
    68401 tttccataca cgagtgtcgg cccaaggacg agtgatccgt accggctgtc ccgaagcggc
    68461 aacgggtcga ggcgacgcca atgccaccgc tcctgactgc cacacgtcat caggggatag
    68521 gcacgatcgc cgaccaacag ctcgatccct gaggccgtga tcagaaattc cccttggcct
    68581 ttcgcgcgct gcagtgctga gcggaccgca ccagtcgcct catagaacac accggtcgtc
    68641 ccgattgcac agccccaggg caattccact cgttcgacat ttgccgtaag atcacaaggc
    68701 agcagccagg cgtcccgccg ttgcttcgcc acccatgcac aggcaagccg gggagccaga
    68761 cacacggact cttgcgtgat ttcccgagcc agccggtgac agagcgccgt taaccgccca
    68821 agaaggagtc gcggctccgg tttgccgttg ggaaaaatct catcggtata cccgtgctcg
    68881 tagaatttct ccctaaactc cgcgcgcaac tgttcggcaa tatccctccg cgaccgttcc
    68941 tgccggacct gggtcacgat atcgacgaaa tacagcaagt cattcagcga ctcgatccat
    69001 cccaccactt tccagttgct aaactcggct ggcgggaaag accgtccgag cgacaggaac
    69061 cagtcgatcg gtaattgaaa cgtgctgact gcgtcggcat aatttttcgt gaaatcgcgg
    69121 cacacctccg tcaacaaccc ttgcatggat cgccggaatt cttccatcaa ccgctcaagc
    69181 atgcgcgcat caagaaccgt catcgctgat cgcctttctg aatcgaagag agccgggcgc
    69241 actctacgcg actgcttgat cgctgacaag catgcaacat gactgcaagc agtgaacacc
    69301 catgacacat tggagagaat tgcgcgggtg gaggggaagc agcagtgaag atatggagcc
    69361 gcagggcgcc gtgggatacg ccaaggcgtc atgcgtggag aacatccccg cgaaaccgga
    69421 gcggcttcgc ggggaaacgc gttacgccga gcgcctgatc aactcaaaga gaaccggctt
    69481 ctcggggaca gaggcaggga ccgggcggag atgggagttc tgcaccatcc ggtgtcgttg
    69541 aatcaacgta tccaccacat taccgcagct gaggcagcgg tgcccacgca accgcatggg
    69601 atgataactt tcctggagat cgaccaaatc gtccatcacc attaggcctt cacatcgcgt
    69661 gcatgtcatg agtcgcctcc cttcgaacag cctctgagat ccccgtcaag acgggacgat
    69721 ctgttgccca ttcgtacaac tcaccaacct ggtgctatgg agagaagcaa tgtggatgcc
    69781 accgactctg gggtgcagag gacgatttgg ccggatgagg cccctgctct caaacgtgag
    69841 cggctcgtgg gaattgagct aattgtgacc gaattggtct catgggacaa aaatgggtag
    69901 aatcggctac acaaccggca acgttccctc ctccggtacg gttcagagaa attgaccggg
    69961 caaatcagga atggccgaag cggcatcgcg gtcaaaaaat ggctcttact gcgacagaaa
    70021 ttggttccat tgtccaggaa ctggcatcag cgctcgccga cgggtggatt cagaagattt
    70081 cccaaccgct tcccgacacc cttatcctcg agatccgtgt ccccggacat actcgccgcc
    70141 tgctctactc actgcgggat gacacggcgc ggctgcatct cgtccatcag catctaccca
    70201 acccgccgac cccaccttcg ttctgccagc tgctccgggc tcggatccaa ggcgcccgca
    70261 tcgataccct tcaacacatg tccggcgatc ggatcgttcg acttgatctc accagccggg
    70321 acggacccgt ttctctcgtc gcagaacttt tcagccgcaa tgcagacctc ctctttctcg
    70381 atggcgaagg cctggtgctc gctacgcttc gtcacaataa agaccgcgta ggtcaaccct
    70441 atcaggcgcc ggcggctgca ccgtttcgat cgtcatccca tcaggcggtc gttcacgagc
    70501 cggatacgca gccgcagacg gacgtggatc catttccgct gtcatccaga ctcgaggcgt
    70561 tctatcgaga gcgcgaagcc gaattgtcgc accaggctca ggcccgcgaa cgggaatcgg
    70621 gactgcgaaa acatctcaaa aagctcctgc gccgcatggc ggctctccgc caagacctcg
    70681 aacaggccgg acgatatgaa ccctacgcac ggtacggcga attgttgaag gccaatctcg
    70741 gcttactgaa gaagggccag aacagggtgg cggtcgtcga ctactacgat gaacaattgc
    70801 cagaactgac gattccgctc gatccgacca aagggccgca ggccaatatg gacgcgtact
    70861 ttgccaagta ccggaagttc gtgaccgcgc aacgcgaaat ctcgccccgc atagctgcga
    70921 tcgaagcaga ggttcaacag acccaaaccg aattggagac catcaaaggg ggcacctggc
    70981 agccaccgag tacggaagga caaaccgcgg tacgaggaac ccctgcccta cgacggaagc
    71041 gcgacaggga gggggaatcc cggggaccgt tccgccgttt tgtctcatcg gacggccatc
    71101 ccatcctggt cggccgcaac gcccgggaga atgatgagct caccttcgga ctggcgaaga
    71161 gcgaagacct ctggcttcac gcgcgcggta cgcccggctc gcatgtggtc gttcggctgg
    71221 acaaggggac cgagccccct cccgaaacca tacgagatgc ggccacactg gccctcctct
    71281 acagcgatct gaagaagagc gggaaaggtg acgtgatcta tacccggcgc aagtgggtca
    71341 aaaaggccaa ggggcaagcg gcaggcgccg tgaccgtgac gcaggaaaaa tctatctatg
    71401 tcacactcga taaaccgcgc ctggatgccc tgaaatccag aagcgcaccg cgatgacgca
    71461 gattcggcca tcctgaatcc ttcatttcac cctgagcgat acaattcctg tccgtccctc
    71521 tccgtcttcc catcactcac cacgacatgg tagagtgccc acatatgggc accgcgttcg
    71581 acacacgtga ctggtttccc attctaagcg cgctccttca aaccaacacc ctccgccagt
    71641 tcgacgatcg actccaacgg gaactcagcc aacgcctagg ctgtagcgtc atcggcctct
    71701 atctctacag tgagatggcg accgcgtttt cacccgtctc ggaaagcttg cgtgatccgg
    71761 cgtcgcccgc ctatcccatc gcgcaattac ccgcgtccgg gaccatcaag gaagcagcgg
    71821 tcctggccgg ggaagcgatc ctgaccggcg atctcagcac gtcaccctgg acggaagccc
    71881 gagccatagc acctcatatc agccatggca catcggtcct cgtctcacca attagaatgt
    71941 catgcgaatc ggtgaccggt acagcagcca agacgctggg cgtcatcgcc gcggtcgcac
    72001 ccggtaaacc gggggcgttt tccgaggagg atcggatatg gctcgaccag ttgagccggc
    72061 acatcgcccc ggttctgacc gccgtgctcg ccgcggaaga acgggacacg ctggtcgcca
    72121 tcaacaatca agtggtgctc ggcactctca cgctcgacaa tctgatccac tcgattcaac
    72181 caatcctccg cgaagtcatc catcacgaca tcaccgggct cgtacggttt gtcggcgaac
    72241 cccacaatcg gtggttcgac atcgtggcgt gcgagggagt cgatatcgac caggacgccc
    72301 tgcggcaatt tccgttcgag cagatggccg ctgccgaaat cctcgccacc ggcaaacccc
    72361 tgctgctcac cggacacaac caggaccgat ttgccgaaca ccggtacttc gaatcactcg
    72421 gggtctactc cgccatgctc tgcccgctcc tggtccaggg agcgccctat ggtttcctgg
    72481 ccatcggaag caaacggcgc aacgcatttt ccgaacgcga cctggcgttg acggaacaaa
    72541 tcggctttca cctgtcccat gccctcacca acctctccgc ctatgaccag atccgacggc
    72601 tcaaggatca actggagcag gagaatgtgt acctgcgtga agaaatgggc gcctccctgg
    72661 atctgaaaag cctcgtgggg gatagccccg cacttcagaa atcgcttcga gccatcgaaa
    72721 tggtcgcgcc cacggattcc acggtgctga ttacgggaga aaccggcacc ggcaaggaac
    72781 tggtggctca ggccattcac cggttgtccc cgcgccggca gaaaaccctg atcacagtga
    72841 actgcgcggc actgccgccc acgctcatcg aatccgaact gttcgggcac gaaaagggtg
    72901 ccttcaccag tgcaacgacc cgcaagctgg gccggttcga actggctcat ggcggaacaa
    72961 tcttcctcga tgaagtcgga gagctgccca ttgatgtcca gatgaaactc ttgcgtgtcc
    73021 tcgaggcgca ggagttcaac cgggttggcg gaagccacac catccgtgta gacgtgcgtg
    73081 tgctcgcggc aacgaacgtc gatctggagc aagccatcaa acgcggcgca ttccgtgccg
    73141 atctctttta tcgtctgaac gtcttccctc ttcgcctgcc gacgctgcgg gaacggcgcg
    73201 aagacatccc gctgctggct cgtcattttg ccaaaaaata cggccttcga catcgtaaac
    73261 cggtgacgcg catcaacagc gcggcattga aagccttatc cgcctatgac tggccgggaa
    73321 atgtccggga actcgagcat ctcatggaac gggcagtgat cgtcagccgg ggctccgtgc
    73381 tgaccatcga agagctggac ggtctgggtc cgagccatga gcggccttcc ccgccgcgca
    73441 ctttggccga agccgagcgg gcacacatcg tagaggtgct ggttcgaacg aattgggttc
    73501 tggcgggaaa gcagggagcc gctgaaacat taggcatgaa gcgatccacc ttgcaacatc
    73561 gcatgaaaaa attagacatt agtcgccctc cgaggcatgt ctcgtaactg cccgcatatg
    73621 ggcaccgctc cttagatctg ccaacatctc ggcagatacc attagagatt cactccaccc
    73681 cacatcctct cctcttcagt attccagcaa attttcatca cgatatgatg ttctggggcc
    73741 accacccttc atccggcatg gcgcatgctt tctgtcgatc ccatgaaatt catcgtgtca
    73801 ccgctgacac cagagtctgt cggtcgtgag attcaggcct atgtcaacga acggcagcgt
    73861 caattgcttc cctccggcga ggtcaccagc gaggggcgcc gtttctcctg gtgcggagac
    73921 attctggact ttctggcaga tggactcgcc gagcgattgg ccccattggg aattactttc
    73981 accaatccat ttccagggcc cttgcgcctg atggatgaag tgcagcaacc cgatggccaa
    74041 catgtacgga gattctggac cgtcgccctg catcggggct gccccattgc cagagtctgc
    74101 acgttgttct tccatcgaca cgatcagatc agccttcctc aggtgccgct cgtgatggcc
    74161 ttttcgcctg accacaccgc cggggaggac ggcgaatgaa ttacgtggcg ctgagaatgc
    74221 tctttggcga tcgcgcgaag tatctcatgc tgctctgcgg gctgaccttc gcagtcatgc
    74281 tgatcgtgca acagggatcg attttctggg gcctcatgat gtggtcgcag tcgagcatca
    74341 gcaatatcaa tgtgccgatc tgggtcaccg accctggcat cggacaggtc gacgaagtca
    74401 aacccattgc ggataccgca gtggatcggg tgcgtagcgt atcaggtgtg gagtgggccg
    74461 ttcccctcta taaaggcgtg ttacgcgctc gcctctccag cggggattat caccagatca
    74521 cgctgaccgg actggacgcc cccacgctca tcgggcgtcc cgccgaagtg ctggaaggac
    74581 ggtttgaaga tattctggaa ccggatgccg tcgtcctgga tcaatgggcg gttgaacgta
    74641 tgggcgggcc ctcggtcatc ggcatcggga cgatttttga gttgaatgac aaactggccc
    74701 gggtggttgc gattgcgaaa acgcagaaaa gcttcacgaa catccccgtg gtctatacca
    74761 cctacgaacg cgcgattcgc tatgtcccgc gtgagcgccg gacgctgtcg tacgtgctcg
    74821 ccaaggcaaa agacggcata cctgcctcag aggtcacctc caggatccat gaacaaaccg
    74881 gactgggagc gttcagcgcc gaagagttcg gctggaagac catcagctgg gttctcaaaa
    74941 ataccgggat cggcatcaac ttcggcacca cgattattct cggctttatc gtcggcatgg
    75001 cgatcgcggg acagacattt tatctgttta ccgtcgaaaa cctgaaacag ttcggtgcgc
    75061 tcaaagcgat gggaacctcc accttcacgc tcgcacggat gattctgctg caagccttta
    75121 cggttggact gacgggttat ggaatcggca tcggccttgc cacgggattc ggatttctct
    75181 cagccaaggg cggcggattg cccttcgttg aaacctggca gttgctgctg ctggtactcc
    75241 tggcgctctt gggcatttgc accctgtcag ccttgatcag cattactaaa ctggcccggc
    75301 ttgaaccggc gatcgtgttt cgatgatgtc gatggatggt ccaggacaca gcgtagcgca
    75361 ggaacagggc atggcttccg tggcagtgca ggtgcgaggc ctggtgaagt cgtttggaac
    75421 cggcgagacc accgtgacag tgctaaaggg gatcgacctc gatgtgcact tcggcgaatt
    75481 actcctcttg gtcggtgagt ccggcggagg caagaccaca ttgctgtcgg ctattgccgg
    75541 gattctcgat atcgacgccg gcgatctcca ggtgctgggg gcgtcgctca caaacatgac
    75601 gcccggcacg cgaaccagtt ttcggggaca gcgcatggga tttgtctttc aacaattcaa
    75661 tctcctgccc gcgctgacgg cggcagagaa cgtcgccatt ccgctgttga tccagggcct
    75721 gcggagaccc gaagccgttt cgcgcgggcg actgatgttg gaacgcgtgg ggctcggcga
    75781 tcgtactgaa tttctgcctc gaaatctctc ggggggacaa caacaacgtg tggccgtcgc
    75841 gcgcgccttg gtcaatgatc cccaactcct ggtctgcgac gaaccgacgg ccgccctcga
    75901 cggacccaac ggacaaaaga tcatggaatt gattcgcgac gtagggcgag cgccaaaccg
    75961 ctgcgtcatc gtcgtgaccc acgacagccg ggtcttccac ttcggtgatc gcatggcgga
    76021 actcacggat ggccgtatcg tgggcattca tccgattcac ccagaggcaa cggcatgacg
    76081 attctcaatc gtgtcagtgt ctggctcgca gttctctgca ccgcatttgc cggctggtct
    76141 gtactcaccg cgggcaatac cgttcccatg ccgacaccgg tcgtggagcc accccgctct
    76201 ccatttgaaa ccaccgtcgc ggcaagcggc attatcgagg cggccaatga gaatgtgcgt
    76261 atcggcccgc cgtctgccgg gctcgtgacc aaggtctttg tcgcagtcgg ggatgcggtg
    76321 cgcgagggcg atccgctctt gcagttagac gatcgcgatc ttcgcgctca gttggtggcc
    76381 aggcaggcag ccatcccgcc ggcagaggcg caaatggaag agcagaagta ccgcatcggc
    76441 gatctcgaca cgcagctcaa acggttgaaa tccgtacggg atagccgggc ggtcagcgac
    76501 gacgatgtca aacgtacctg gtatgccgcg gaaatggcca aacgcgccat gagtcggttt
    76561 caggcggcgc tgaaacaggt cattgcacaa cgggatgaaa cccagttgct gctggatcgg
    76621 ctgacggttc gcgcgccccg cgccggcacg atcctgcagg tgaatatccg ggcgggagag
    76681 tttgcgctga cgacaggtgc gaccgagcca ctcatgctct tgggcgacat gcaacaattg
    76741 caggtccgtg cggaagtgga tgaagtcaat gccccgctcg tcgccccgca gcggccggcc
    76801 gtcgcctact tgaagggcaa cacggctcaa accattccgt tgaccttcgt gcgcatcgaa
    76861 ccgtacatcg tcccgaaaaa atccctgacc ggtgacaaca acgaacgggt agacacccgc
    76921 gtcctccaga ttatctatcg ctttgaacgg cccgcgttcc ctgtgtatgc gggacagcaa
    76981 gttgatgtgt tcatcgaacg gactccagcc ggtgggccgc cccaaacaca gcccgttgaa
    77041 cgtcgcggtg aggtgtcgcg gaaatgaatc ggtggattct tgcatctcgg gcggccaccg
    77101 cagtcctcat gacactgacc gtgtcgttaa ccggctgcct gcaagggaag gcctatacac
    77161 gtccgtcggt tgacacgccc gccgactgga ctcatgtcgc ctccggccct ctcgtctcag
    77221 gcacctcccc aaaaactcct gacgccgatt ggtggaaagc atttcgaaac gaggaactca
    77281 cgcaattcgt cgagcgcgcc ctcgcgcgca atcacgatgt gcgtcgggcg gtctcccgtg
    77341 tgatcgaggg acgcgcatca gtgaccacgg ccggagcagg actctacccg caagtgaacg
    77401 tgcagagcag ttacaccaac atctccatct cgaaaaatac cttggcggga cttggattag
    77461 ccaccggcca gcaaccgggc ccgcaggtct tcgccagacc gggcagcagt tttgaccttt
    77521 ggaacggagc cgccgatctg cgatgggaac tcgatgtgtg gggtcggatc cgtcgcggaa
    77581 tggaagctgc ctcggccgat gcacaggcga tcgaacagga tgcgcgggcg atcgccctga
    77641 ccttgatcgg cgatgtgggg caagcctatt ttcggattcg cgagttggat gagcagatcg
    77701 aaatcgcgca acgcgccctg gctttgcggc gagactccct ggagatcatc accaaacggg
    77761 cgtccgtggg attggcctcc gaccttgatg tgaaacgaac ggaagtcctc gtcgccgaaa
    77821 gcgcgggaca aattcccgat ttggttcgct tgcgtacggt ggaagtccat cggctggaag
    77881 tgctgaccgg atcagcaccc ggcggcctga ctctcgcatc gatgccgctg agaaaagtgg
    77941 tcgtccagcc cgacattcca gtcggcctgc ccgcacagtt gctggaacgg cggccggaca
    78001 tcctgcaggc cgaggcgact ctcatcgccg cgaatgcccg tatcggccag gcacgggcct
    78061 atttctttcc caccttctcc atcacgggcc aaggaggcct gcagagcgcc gagtttgcca
    78121 attggttcac cggcaacagc gccaacttca gcatcggccc atccgtcacc ttgcccattt
    78181 ttctcggggg gaccaatgtc gcacggctgg atgcggcgga atcccgctat caacaaatgt
    78241 tggaaggcta ccaacagacg attctgctcg cctttcgaga agtcgccgat ctcctcgtgt
    78301 cgatccaagc ccgcgccgag caactgacac gccagcgtga gcaggcggtc gccgcgacgg
    78361 ccgccgttgg cctggcggaa gtgcgttatc gaaaggggct ggtgaattat ctcgatgtcc
    78421 tggatgcgca gcggacgatg ctggcggcgg agacacagct cgcacaaacg gagcgggcgc
    78481 gcctcaccga tatggtgagc ctctataaag cgttgggcgg cggatggtcg caacctcccg
    78541 gaatcacttc tgtcccggca tcgagttcga tgacacggtg accctttctc ccccgtccct
    78601 actcatatca tcagccgggc accgcgacgc cgcggacttt caacttgaat tttccggcca
    78661 gatcgggcta tctgacgcag tgcaatccct gacccccgat caagcggcag gccagacacc
    78721 ggccagcctt ttcacgctaa tgcctctctg acttctcgga aggagcctcc catgcgagac
    78781 ggtgtccgcg gccagcgttt ggcacgcccc ctgtatcctg cttcgatcat tttggcattg
    78841 gggcttgtcc tcccattcag cacacaggcc tcttccgcct cgcaggaaac ctctgcggca
    78901 aaatccggca tcgccgggac aaaccttttg gaggaggagc agattctctc gaccaccgat
    78961 aagatcacac aaccgatcga tactgatgcg gaggccatgc ggcacaatga tctcggcgtc
    79021 gctttcgtct tcaaagggga tgtaggacag gccatcgacg aattcaccca tgccctccgg
    79081 ctccaaccga actattttgc cgcgcatctg aatctggcta acacactgct tgatatcggt
    79141 cggcatgatg ccgccatgat tgaattcaaa gaagccttgc ggctgaagcc ggatgacccc
    79201 aagacgcaca atgatctggg ggtggcactc aaggaaatgg gcgatccggc gggggccatc
    79261 gcggaattca aaaccgtgtt acgccgtaat cccaccgatg tgaatgccca caacaacctg
    79321 ggggtggcgc tcaaggccat gggtgatctg gatggggcga ttgcagaata tcgcactgcg
    79381 gcgagcttgc aaccgaacga tgtgaacgcc cactttaacc tggggctcgg gctgatggag
    79441 aagcatcaac cggatgcagc catcgccgaa ttccgtacgg cactgcacct ccgccccaac
    79501 gatgccaaga tccgcttcaa ccttgcgcac gcactcgccg gtcttgggca acgcatggag
    79561 gccgcccagg aactccggca ataccttcgg ctcgaactcg acacgccggc caatcgtcga
    79621 tggttggaac aggccgaagc caaactacgc gaactggaaa tgccgtaa
//
LOCUS       DAOQPD010000007        77013 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_101_length_77013_cov_21.569090, whole genome shotgun sequence.
ACCESSION   DAOQPD010000007 DAOQPD010000000
VERSION     DAOQPD010000007.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 77013)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 77013)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77013
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_101_length_77013_cov_21.569090"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..573
                     /locus_tag="PK063_03085"
     CDS             <1..573
                     /locus_tag="PK063_03085"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96053.1"
                     /translation="RPSLPSSFVRFFLHPQVLSIASTYLGLQVRLNYTDVWHNIPVRE
                     GEPPISAEFWHRDHEDKRVIKLFVFLTDVDETMGPFTYVRRSQVGGEFGHVYPAIPPI
                     GRYPEQDALSQLITGTPLPSVSCVGPAGSIILCDTSGLHRGGRSVTKPRIVLVGVYTS
                     NAGMDAARYALPRSLPHEHLSPAAKFALYS"
     gene            705..1253
                     /locus_tag="PK063_03090"
     CDS             705..1253
                     /locus_tag="PK063_03090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HMZ96054.1"
                     /translation="MGERIQVSGRVVRCVGLLAAAFVAAGWLGAAQAADELPKESVLP
                     AALAGKAVQAALDACKKDGYRVSASVVDRAGVLRAMLRADGAGPHTVDSSRKKAYTAA
                     SLRRATSELADMIAKQPALQALREMNESILMVGGGLPIEIAGEVVGAIGVGGAPGTHL
                     DDACAEAGLDAIGAASKMPAAK"
     gene            1259..1714
                     /locus_tag="PK063_03095"
     CDS             1259..1714
                     /locus_tag="PK063_03095"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96055.1"
                     /translation="MQRRGPALLVMGLVLLLAACNSDRPEPAEADVPSAGLRLRVTRV
                     ATHPFLSRYRLTLQVEGSRGCTDTAELFPDTGYAGRRNVYAQASGAITLLGQYDARVI
                     DPAQCRIRLVEFQSVGEPSKFLGAFDVDAEKRWQFIPASMRPERPFEKH"
     gene            complement(1722..2621)
                     /locus_tag="PK063_03100"
     CDS             complement(1722..2621)
                     /locus_tag="PK063_03100"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HMZ96056.1"
                     /translation="MAQAEFRIGIVGVGRMGANMARRLHDLTYQLVAVYDTEASRAET
                     LANELGCVAAPTPARVAELANTILTVVPDDAAMRHIYAPNTPDSLLRHATGRLFINCA
                     TLSPAAQMEVHRLVEQQGGHSLEACMASSIPQARHGTLYLMCGGRRDVFERATPLLKD
                     LSAHLRFIGPAGDAAKVKALVNMVMNANTAALAEGLGLASALGLDLTMLREVFSQTGA
                     NSRVLETDGEDMQQRAHDCYFSAAHAAKDSGIACSLAEQVGLELPLAKATYDQYRRLV
                     TLGKGELDKSAVAELTFKERLTS"
     gene            2749..2970
                     /locus_tag="PK063_03105"
     CDS             2749..2970
                     /locus_tag="PK063_03105"
                     /inference="COORDINATES: protein motif:HMM:NF023510.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3565 domain-containing protein"
                     /protein_id="HMZ96057.1"
                     /translation="MQQSIIGYHQDEEGHWVADLRCGHGQHVRHQPPMTSRPWVLTEE
                     GRQVFIGTELNCKKCDEGGDGFSPAEPLS"
     gene            complement(3049..3864)
                     /locus_tag="PK063_03110"
     CDS             complement(3049..3864)
                     /locus_tag="PK063_03110"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96058.1"
                     /translation="MQSITPHPRLRSVFTLCWMVGGAALTLGGCVSQQTYDTARHEVK
                     TRAGELAQTQADIHSLEQEREAAHLANQRDERTLANLKSELKTIQASYDQLHKANQAK
                     LALLEHNIAALRAKHQAMLKEIGDTKRIEKRLEGLTTLRDRTMGTQQSGPEAQATPVD
                     ISSPEQHMVAVITPQPSQADASSLPPIPATVPAQLPPAPAAAAAPAPATSSAAPAAVA
                     PATPNAPAKVSQAPAAAAAPPAPRPVPAAPPAEESWFSSVTGWFSSLIDWLWA"
     gene            complement(4038..5138)
                     /locus_tag="PK063_03115"
     CDS             complement(4038..5138)
                     /locus_tag="PK063_03115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide epimerase"
                     /protein_id="HMZ96059.1"
                     /translation="MNSDIIQRIEIWPVDIPITDPFVVATGARVTAQNLFMRVTLKDG
                     THGVGEAAPFPEVGGEDRASCLAAAQKLAAGLIGHSAGDYEALADHLTEQAPLFPAAR
                     CGLETALLDAYCRSQRLPLWQLWGKADVRERETDITIPICDLDKTLALSRGWYAQGFR
                     LFKMKVGTDVEEDIRRLQAVHEALPGISFIGDGNQGFSREDCIHFAGRVKQFGGRLIL
                     LEQPVVRDDLEGLHAIRHLTGIPVAADESVRSLDDARRVVRMQAADYINIKIMKTGVI
                     EARRIADFTRSSGLRLMVGGMLETRIAMGCSFSLVLGLGDFDVLDLDTPLLLSTDPVI
                     GGYRYQGPRLLPWQEAGLNMQMAVPTHCLTIQ"
     gene            complement(5167..5811)
                     /locus_tag="PK063_03120"
     CDS             complement(5167..5811)
                     /locus_tag="PK063_03120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite oxidase-like oxidoreductase"
                     /protein_id="HMZ96060.1"
                     /translation="MDQNDRLIKTKENWAKARRGGEEREVFYEGDDRLPPGQHLVETW
                     PVLDLGQKPDIPLTEWTLTIGGAVAAPMTWTWTDFLAQPQFKDISDFHCVTSWSRYDN
                     EWEGVSFKHVAAVVQPHPSARFVLFKSYDDYTTNLPLSACLDDDVLLTYKWNGRPLTK
                     DHGGPVRMIIPKRYAWKGAKWIKEITFSQHDEKGFWEVRGYSNTALPWQNDRYG"
     gene            complement(6048..6197)
                     /locus_tag="PK063_03125"
     CDS             complement(6048..6197)
                     /locus_tag="PK063_03125"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96061.1"
                     /translation="MGPLSVHDMKGGFFLIASFVLLATICAIAALGTLMRPQRWCERE
                     TRLHV"
     gene            6634..7350
                     /locus_tag="PK063_03130"
     CDS             6634..7350
                     /locus_tag="PK063_03130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HMZ96062.1"
                     /translation="MTISADSSLPKARAGSGKLVLALLVGCAVAGFLYFDLGRYLSLD
                     ALKANRDQLLAFTEANYSTAVAVYVLAYCAVVGLSLPGGAIMTLAGGFLFGSVLGTLY
                     VNVGATVGATLAFLVARYLLRDWVERQFGSRLGAIQEGFSRNAFSYLLTLRLIPLFPF
                     FLVNMVSGLTRVNVGTYVAATSLGIIPGSFVFAYAGRQLGTINSLKEIVSPNVLIAFT
                     LLGLLALVPILYKRFAGHSS"
     gene            7402..8964
                     /locus_tag="PK063_03135"
     CDS             7402..8964
                     /locus_tag="PK063_03135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mercuric reductase"
                     /protein_id="HMZ96063.1"
                     /translation="MSVRTADSQHLVLPDDEHNRKLVGNVHPSNWVNPESDGRYNIVV
                     VGAGTAGLITAVIAASVGAKVALIERHLMGGDCLNVGCVPSKGLIRAANAWAQVRDAP
                     VFGARIPDGASFDFGAAMARMRQLRARISHVDSAHRYKSLGVDVYIGQARFVGPDTVS
                     VEGAAGNRTLAFVKAAVCTGARAAAPPIPGLDEAGYLTNETIFSLTALPARVGVIGAG
                     PIGCELAQALARFGSRVSLIEAMHGILPNEDRDAAECVQQSMIRDGVALLCCGKDLRV
                     EKVSDGKRLIVDSHGRHHDLTVDEILVGVGRAPNVQGLGLEAVGVEFDKTGVTVNDRL
                     QTTNPRIYAAGDVCSRYKFTHAADAMAQILIQNALFPHPFGLGYASMASLNMPWCTFT
                     SPEIAHVGLYEAEAVKQGLQVETYTYKFDEVDRAILDGDEEGFARLHIKAGTDTILGA
                     TIVGSHAGDVISEVSVAMKAGVGAKTIAATIHPYPTRAEVIKKTVNLWRKAHFTPRTK
                     SLLTKLFAWLRR"
     gene            8971..9708
                     /locus_tag="PK063_03140"
     CDS             8971..9708
                     /locus_tag="PK063_03140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3047 domain-containing protein"
                     /protein_id="HMZ96064.1"
                     /translation="MRPIGPILCLALFGATVMGEAQQPALLPVGTFSAATEGSALPDG
                     WHMLTFKKIERHTQYDVIKDQAISVVRAVSEAGASGLTKAVTIDPREYPIVRWRWKIE
                     NVLNKSDVSRKEGDDYPARLYITFAYEPDRVSFGKKLKYKAGQALFGDIPIAALNYIW
                     DSKSPVGTVVDNAFTSFAKMIVVESGARRIGSWIEEERNVYQDYLSAFGEEPPAINGI
                     AIMTDTDNTKERAVAFYGDIEFVRAPK"
     gene            complement(9811..10224)
                     /locus_tag="PK063_03145"
     CDS             complement(9811..10224)
                     /locus_tag="PK063_03145"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96065.1"
                     /translation="MKINVETSWLGIAVATLATISFAVAPASAKEKDKSGKHHPPAAT
                     TSAAAAASLLGSVPEQSAAVKPGQYDSKPGVAWKTVGGTVKDIQGETYTVEDYDGSQM
                     KVRVGQGTKQLRGHKKVGDTIRAEITHGGFANSIQ"
     gene            10551..10868
                     /locus_tag="PK063_03150"
     CDS             10551..10868
                     /locus_tag="PK063_03150"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96066.1"
                     /translation="MKQVIWSVAILSMCVPSLVFAQAETPRIDQRQANQERRIDQGIA
                     SGQLNEREATRLNNQQEHINNIEDKAKSDGVVTKKERARIKHAQDRTSRHIARQKHDR
                     QQR"
     gene            11102..13762
                     /locus_tag="PK063_03155"
     CDS             11102..13762
                     /locus_tag="PK063_03155"
                     /inference="COORDINATES: protein motif:HMM:NF013528.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HMZ96067.1"
                     /translation="MDLITTHLNADFDGLASMVAARKLYPGALLVFPGGTQESVRKFL
                     ADHDLGICRLKDVALEHVHRLILVDVQEPERIGPLKVLSSRKDLDVHIFDHHGNGEGV
                     ETSAWASKTQRHIEPVGATATLLIERLQSQQVVLTAAEATVLAMGLYEETGSLAYPTT
                     TPRDLEAAAFVLRAGADLNRVAETLQHPLDPDLIALLNDLLQSGEIYYLEGRKILVAS
                     SAYDRYTGDLAEAVQRLAELQGFDAVIVAIAMDEKVQIIGRSRRPEIDVAWIAREFGG
                     GGHAVAAAASVKGRTLVEVQEQLTRLLTERYRPTLLARDVMTTPVKSIVADATVTEAE
                     RSMTTYGVNVLPVVDTKDRYIGMISRETVQKALFHQLGDQPVGDLAGSGHYSASPDTP
                     FHDIETRMIELNQRFVPVLSDGKIVGVITRTDLLRSLHDDVLASARSKPKSFIGLESP
                     GGVRKRDLKGLLRDRLPPRVHDLLHASGVLAERLGLSLYVVGGFVRDLLLGLENLDVD
                     LVVEGDGIAFARALAKERAGRVKVHERFGTAVVLLPDGFKIDVATARTEYYEYPTALP
                     TVEQSSIKKDLYRRDFTINTLAVALRPRNFGQLIDFYGGQRDLKERLIRVLHSLSFVE
                     DPTRVFRAIRFELRFDFHLSKDTLALIKGAVKMELFHRLSGQRLLDELRLLFSERTPR
                     QAVRRLADLDLLRFIHPTLTWSARLDRRLSELEAALDWYRLSCLDRTIDGWVVYAMAL
                     AETMPDEAVRDMLERFPFTEAERTAINQARFLTQPVCRTLARRAPLRPSETVAALAGF
                     SEECLVFLLAKNGSDTAKRSLSQYLTTYRDIKPALTGKALQALGLKPGPVYRTILERL
                     TEARLNGEVHTEEEERALVKDLIARRRSAS"
     gene            complement(13864..14064)
                     /locus_tag="PK063_03160"
     CDS             complement(13864..14064)
                     /locus_tag="PK063_03160"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96068.1"
                     /translation="MDTTLTPRQITHDEKKAAEAAFAGRPFNPKWSDAARIVYDGLLA
                     AMGKEARAVDTHDELEPVEPLA"
     gene            complement(14185..15162)
                     /locus_tag="PK063_03165"
     CDS             complement(14185..15162)
                     /locus_tag="PK063_03165"
                     /inference="COORDINATES: protein motif:HMM:TIGR00724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase family
                     protein"
                     /protein_id="HMZ96069.1"
                     /translation="MPTKQPLIHVLHPGLFTTVQDLGRSGYQRFGVSVSGAMDPWALM
                     VGNRLLGNPDQAAGLEITLQGPQLLFEQAVRIAITGADLSPTSNGLALPMWTVVAMPA
                     GSRLQFGMRRQGARAYLTVAGGITGPMILGSLSTHVRSGLGGLAGRAVKKWDQLFVGT
                     ASRAAAQPIGRSLPERYRPRYTGSPAVRVMPGPQSDYFTDDAIRLLTSSPYRVTTESD
                     RMGYRLEGAELPHRASAEIVSEAVCVGSLQVPSNRQPILLMADCQPTGGYAKLATMIG
                     ADRSLAAQLAPGDTLSFRMISAEKASELFRSTYAELDRILPPAVLGAKP"
     gene            complement(15152..15928)
                     /locus_tag="PK063_03170"
     CDS             complement(15152..15928)
                     /locus_tag="PK063_03170"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_function: GO:0017168 - 5-oxoprolinase (ATP-hydrolyzing)
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpA"
                     /protein_id="HMZ96070.1"
                     /translation="MTRLRHIDLNCDVGEAATPEQRDVEARLMPYVTSVNIACGVHAG
                     DAALMRSTIQLARQYDLAIGAHPGLPDRESRGRRELPLSQGFVLDLILSQVSDLMTIG
                     QAEGIRLSHVKPHGALYNMAARDPELADAIAAAIVQLNRRLILIGSAGSELLTSGRAH
                     GLAVAAEGFVDRAYQADGRLVPRTEAHAVLHDESTVLARAHALVHDGTVVAANGTMLH
                     LHIDTLCLHGDTPDALRLAHALRTMFAESGISVRRLDHAD"
     gene            complement(15925..16611)
                     /gene="pxpB"
                     /locus_tag="PK063_03175"
     CDS             complement(15925..16611)
                     /gene="pxpB"
                     /locus_tag="PK063_03175"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: protein motif:HMM:TIGR00370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HMZ96071.1"
                     /translation="MIPRMIQLSESAVTVEFGDGIDLHTNELVLAFTAAVDQSKIPGF
                     REVVPTYRSATVYFDPLLTDADTLMKKVRALTVDTVVAPSRASITHTIPVWYGGAAGP
                     DLPDVARQAGLTPEEAGELHASVAYRVCMLGFSPGFPYLSTVPAPLAAPRLPTPRKYV
                     AAGSVGIAGTQTGVYPQASPGGWRIIGRTPVVLFDLHRPKPFLLAPGDQVRFVAIEEE
                     EFTQLAGDQA"
     gene            complement(16658..17929)
                     /locus_tag="PK063_03180"
     CDS             complement(16658..17929)
                     /locus_tag="PK063_03180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HMZ96072.1"
                     /translation="MHGVTTYQWLVLFVAWLGWVFDAMDATIYAIVLHPALHELLQAG
                     ATGGEVTSEQIGWYGGIVFSVFLIGWALGGIGFGMAADYFGRTKTLIATILIYAVFTG
                     LAALAQEWWHLAIYRFLTALGVGGEWAAGAAIVAETWPEEKRSRAAGILQSAWAFGFF
                     IAAGCNLLLKDSGWRMLFLIGILPAFVALLVRRWVKEPERWVQAHEREPRSAHTSWLH
                     LVELFRPSLRRDTLIGSTLAFVAVFGVWGATNWAPTLIRGMPDLQGQDSAALAEKVSY
                     AIMALNAGALFGYLGFGPLAERFGRRPVFGLMCLGSLILLPATYFVPHSYAEVLLLLP
                     VLGFFNNGIFSGFPIYLPELYPTRLRATGSGFCFNAGRILASAAPFVTGWLVTMLGSF
                     NNAASTIALIYLLGLAILPFATETKGRPLPE"
     gene            18043..18681
                     /locus_tag="PK063_03185"
     CDS             18043..18681
                     /locus_tag="PK063_03185"
                     /inference="COORDINATES: protein motif:HMM:NF012451.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaJ domain-containing protein"
                     /protein_id="HMZ96073.1"
                     /translation="MPRIDYYRVLGVSRDISDDEIKKAYRKLVFEHHPDRNPNNSKAE
                     EKIREINSAYEVLGDPESRRTYDRLHWGEEMRPETVDPALILEEMEKKLFDEGRKEVF
                     AVLMKMVPRIKSELAIIRERTVAHQGYDTFKEPIVEARGAEVLDEFVTPEMEQRKHRL
                     LEVAVQMMVSQSVVARGDEGGIRALRGRLEEMFRKGRINGFATALELLYQRR"
     gene            complement(18772..19980)
                     /locus_tag="PK063_03190"
     CDS             complement(18772..19980)
                     /locus_tag="PK063_03190"
                     /inference="COORDINATES: protein motif:HMM:NF014081.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HMZ96074.1"
                     /translation="MTIAIRQIRILDGQGRKIERGTVVIEGDRIVAAGPDQTVRLPRG
                     AQRIDGRGLTILPGLIDCHVHFCLGAEADVVAAVEQESSAVTLLKAAELARRTVQAGF
                     TTVRDVGFRDHAVFALKKAIASGLTPGPRILAAGLAICMPGGHARFIGREAQGIEAVR
                     AAVQDQLTAGAEVIKVIASGGVLTPGTSPDEAQMTVEELRAAVEVAAAHGRHVAAHAH
                     GASGMKNALRAGVHSIEHATLMDEEAAGLMTQRGVYMVPTLSALATTAACPTGCGIPD
                     SARSKAKNMVRQHEKSFRAAVRRGVPIALGTDAGTPFNYHGDNAQELERMVTLGMTPM
                     DAIMTSTSAAARLLRLSAEIGTIEAGKQADLLVVEGNPLRNIGLLLKRERIAGVMQGG
                     RFVSGPLSET"
     gene            complement(19977..20579)
                     /locus_tag="PK063_03195"
     CDS             complement(19977..20579)
                     /locus_tag="PK063_03195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3365 domain-containing protein"
                     /protein_id="HMZ96075.1"
                     /translation="MSRNGFWIVMAGVAGFVAAITYWVIALAVAESRKADMVAPERVT
                     SFIHAVIDANRANYTQNVVDKLHTQGVVEALEHWKEEKGLPLPAQFLLESGRLVAQKD
                     MKLSFRLASLTPIYVWNGPNSEFERRGLEVVMKAPEKPFTGFYQQGGVRYFQGIYADR
                     AVSESCVSCHNGHANSPRRDYKLNDIMGGVIVTIPISEAP"
     gene            complement(20576..21793)
                     /locus_tag="PK063_03200"
     CDS             complement(20576..21793)
                     /locus_tag="PK063_03200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HMZ96076.1"
                     /translation="MSLSSHDHAFVPPHRLLMGPGPSMVHARVLHALSQPLVGHLDPI
                     FLNLMNTIQASLRTLFRTENEFTIALPGTGSAGMEAVIANLIEPGDRAIVGVNGVFGS
                     RLATMIERSGGIPLRIEAPWGQIISLDAVHDALSRGGPVKAVVLVHAETSTGAWQPLE
                     DVGALCRAHGALLIIDAVTSLGGLPVEVDAWGIDACYSGTQKCVSCPPGLAPLTVSPR
                     AMEAVRQRRTPCHSWYLDLSLIAEYWNDRSRAYHHTAPISMLYGLHEALRLIHEEGLS
                     PRFIRHQLNSDALLAGLEPLGLRPLPPAAHRLPMLSCVTLPEGIDDTLVRTQLLQDHG
                     IEIGGGLGPLRGRVWRIGLMGESCQQAHVLTLLNALEDIFAQHGWLDQPGRAVQAAVE
                     TYTQSQLSARRGA"
     gene            22006..23499
                     /locus_tag="PK063_03205"
     CDS             22006..23499
                     /locus_tag="PK063_03205"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF014566.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HMZ96077.1"
                     /translation="MDADESTGPVSQSSRPPAPCVGAPPPPHAYNPGFSRAVTLLSAV
                     VLSASIAVVAWLSFDIPRVERVADPGRALSHMVGRLMDQADGVKTLPVWEQFLYDLTM
                     GSDANDREQAIEWYRELAEESSDPFVDLHLAILEGEAGHLPEVRQRISRWIRQSAPYP
                     LFARLLQAGYVDAHVARSAGFDLQASLAEQPVSGWFYSRLAARIAERAGDRPLLVTIE
                     TADQQRIETLVWRSRAFALLELGLMVVGGMVLMVWVRRGTGANMFRVGSAELPPLWAG
                     RLGAGVLLRGGAVGALLTVAFLFAAGDVPSLRVVAVPLSNLPLLALAYYHLLRPQRQT
                     FWRGLGLSLEPRHVGQLSLAVLAVVAAGLVGEWVLGRLAEPLNLISHWTEWFDADLVW
                     GTPPTLIVSLMEYVVFAPVFEELAFRGLLFGVFRRRFQWGTAAMLSAALFAIAHGYGL
                     IGFLSVFWSGVIWAWAYERTGSLWPGMIGHAVNNLLVCLSVMALLRP"
     gene            complement(23586..24194)
                     /locus_tag="PK063_03210"
     CDS             complement(23586..24194)
                     /locus_tag="PK063_03210"
                     /inference="COORDINATES: protein motif:HMM:NF019498.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HMZ96078.1"
                     /translation="MTATKKTKPLKRASPPATKAEVHVGDIVRRLRKSHHLSVRTLAD
                     KCGFSPSFISQVELRQASPSIASTEKIASALGVTLGEFFRAIDPTPPAIIRSDSRPVV
                     QSEWSRAKIEALGPFNKDSQFEPMVITIQPGGASGHKPYVRQAEQLAVVLMGSLELTL
                     EEDVHQLKRGDAAGIPAGNRHCWRNISKRPAQILIVTAHRRL"
     gene            24482..25828
                     /locus_tag="PK063_03215"
     CDS             24482..25828
                     /locus_tag="PK063_03215"
                     /inference="COORDINATES: protein motif:HMM:NF024863.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HMZ96079.1"
                     /translation="MTHPDAMWGGSLKDKATWLTLTIFVSACALLWLTGVTSTKHLVD
                     NLIAGYLLSWGLYAFLSDLPRREIQGRFILMTLCGIVVLGTAELLGVTGLVNYQMLFG
                     TQGREWFDRSGYVRDPELGYRRQAHYQEEGAFVRGNIGEALCLPANAPQRFDLRYDHR
                     GFRNDTDLDRAEVVVIGDSYVESPMLPGDSLLTTQLSHRLRTSVANLGISGYGPEQEL
                     VVLKRYALDLQPKTIVWVFFEGNDLYQLDPEEQNLSAVPDTRAEHDEYWMRSLTRNLL
                     LLSRKAVQGCVPHPDYLRLRGTFHDTEGNETLLYFWERLGELKPTDRLRLERLRSILT
                     EAYHVSRQQGIRLVVAFAPVKHRVHQGLKNFEPLTAEMREWPLNELPDEVASMLNTLS
                     PDIEFIDLTPPLREAAAQGVLTYLPDDTHWTAEGQRVAGEAIHHLLAGGQTRVAKQ"
     gene            complement(25836..26738)
                     /locus_tag="PK063_03220"
     CDS             complement(25836..26738)
                     /locus_tag="PK063_03220"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96080.1"
                     /translation="MRLCPETRTRIGSNRQQQTNRQFGYDARMPSLRPIVILGTGYTG
                     RWIQKLAREQSLPILASSRQPEHHLSDIAQTARIRFDLESPSTWSALPLDADLIWTFP
                     AVPLEQVKAFATHSCSHSRRLVVLGSTSAYDRGDEPLTDMPPWIDETCPVNVDLPRVQ
                     GEEYLRTKHGGIILRVAGIYGPHRNPVEWIRQGRVGPTNKFVNLIHVEDLAALCLLAL
                     QIGRAGDIYNISDGLPRRWTEICVEVSTRWGIVSPREATSSQPGKRINNRKALEGLRY
                     TLRHPDLYRTLATLQQESGVRNCP"
     gene            26795..27898
                     /locus_tag="PK063_03225"
     CDS             26795..27898
                     /locus_tag="PK063_03225"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ96081.1"
                     /translation="MIGRPTDAQAQRRQRILAGLAGLLACLFFVLDLQLPLGVANAVL
                     YSAVVLLSSASQYRWLPIATATACSLLTIIAIPFSPRIPNLPPWFEWVNHLFSLFGVW
                     APVVFVYQRRRTERLLEEINERLERGVETRTADLAASRLALERSEEQLHTLTGRILTA
                     QEEERRRIAQDLHDDVNQRLALLMLELQSVDRQIGVSPVAAQDGIHNVLKGLEALSDD
                     VRYMAYRFHPSILDDLGLKAALQRLLDDFSTRTGVKALFVHQPLDHPLDKTASTALYR
                     VVQESLSNIARHAKATRVEVEVTVEEEGVVVVVRDDGKGFDQLTVERCEGGLGLLNMR
                     ERLLSVQGTCEVESSPGKGTTVSMYVPLVRVAI"
     gene            27895..28539
                     /locus_tag="PK063_03230"
     CDS             27895..28539
                     /locus_tag="PK063_03230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ96082.1"
                     /translation="MTLPRVLLADDHTLVLEGFRRLLDDQCELVGTVGDGRSLLEAVP
                     QLKPDIVILDISMPVLNGIDAARVMKVKFPQVKVVFITMHADPAYVRAAFEAGASAYL
                     LKRCVGEELAQAIRAVRSGNFYVTPLVTKEVVESMLRGVDGGAPSGPELTTRQREVLQ
                     LLAEGHTVKDIAGTLKISPRTVEFHKGQIMEQLNLHTTVELVKYALAQGLTSQT"
     gene            28691..29122
                     /locus_tag="PK063_03235"
     CDS             28691..29122
                     /locus_tag="PK063_03235"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ96083.1"
                     /translation="MRKKISRPRVLLGDSSRSMLAFLEILLESHFDVVGSETEGDALV
                     LTAKTLAPELVILDFSLSFLDGLSVGRQLQEAVPDSKVVFFSSHEDAAYVTAAFEVGA
                     MGYLVKHRTVDPGHYLRRVLDGERVCCPDDLHKRVGRPKKK"
     gene            29558..34009
                     /locus_tag="PK063_03240"
     CDS             29558..34009
                     /locus_tag="PK063_03240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HMZ96084.1"
                     /translation="MTPVLPFHPIIADWFTAKFAVATDVQQQAWPEIQSGRDLLISAP
                     TGSGKTLAAFLSCIDRLFQQALRCDLRDETQILYVSPLKALSNDVQKNLQQPLLEIGQ
                     AALSAGLLLPDLRVIVRTGDTPMSERQQMLKRPPHILITTPESLFILLTAEKSRAMLK
                     TVRTVIVDEVHAVAPNKRGAHLALSLERVAALAGGAVQRIGLSATQRPIERMGHFLVG
                     NRSSSPQTQDEHSAAGCSGDEMPVANHVAIIDVGHRRDMDLAVEVPKDELGPVATNAI
                     WSDIYDRVAALVEAHRSTLVFVNTRRLAERVSHYLEDRLRHLGEGVVAAHHGSLSREI
                     RLSAEDRLKTGAVRVVVATASLELGIDVGTVDLVCQIGSPRSIATCLQRVGRAGHWVH
                     AIPKGRLFATTRDELIECAALIRSIRAGVLDHIEVPPAPLDVLAQQIVAASATQAWDE
                     TELYKLCCRAMPFRDLTRETFDAVIAMLADGFATSRGRGRAYVHHDRINHQIRGRRGA
                     RLAAITSGGAIPDTANYAVIAEPDGTVVGSVDEDFAVESLAGDIILLGNTSWRIKGVE
                     TGKMRVEDAQGAPPTIPFWRGEAPARTADLSAEVARLRADLDHRLDPNVPAPPPSAPP
                     VQWLKQECGLDQRGAEQAVQYILAGKSVLGTVPTQHTIVAERFFDESGGMQLVIHAPF
                     GGRVNRAWGLALRKRFCVTFDFELQAAATDEGIVLSLGEKHSFPLETVFAFLNVKTLR
                     DVLTQAVLQAPMFMTRWRWNASRALALLRFAGGKRVPPQIQRMRAEDLLAAVFPDAIA
                     CQDNFQGERTERQIPDHPLAQETIRDCLTEAMDIDGLAAVLNRIESGAIACVAVDTPM
                     PSAFCHEILNANPYAYLDDAPLEERRARAVDMRRTLPAALAGEMGALDQSAIDQVREE
                     SWPDVRDAEELHDALLTLGWVPCACMPGWDLLVPRLEVAGRVATLWRGDNKQGWVAAE
                     NHQYGGLLFPDTRIDPESAPTHEPLLEREEVLQRIVLGWMESVGPVTAADLAARLGLT
                     VPDVDGAMLRLEAQGHVLRGRFSTQVSHTTDGVVEWCHRRLLARIHRLTVGRLRKEIE
                     PVTAAEFMRFLFQWQHASPGARLHGEAGLLEVAKQLGGFEAAASAWEAQILRVRLAKY
                     QPEWLDRLCLGGALMWGRITPHPRLMQELALLPGRRVVPTRVAPVSLFAREDAPVLLE
                     ATGEDLARLDLSSKLSVSAQAIRHCLQQRGASFFSELLHGARLLASEVEDGLWELVAA
                     GLVTADGFDNLRALIDPRRRRAEASDRNRRPRHVGGRWSLLRPAVGQSQTGPQAATTL
                     RASSSSAHVVGSSERAQATERIARQLLQRYGVVFRDLLARESIVSSWRDLLVCYRRLE
                     STGELRGGRFVSGFTGEQFALPEALEALRALKKRPGTATQQEIKISAADPLNLAGIIL
                     PGPRIAAVPSNFVVFREGVVIRTVTGRSATDRQEPPILEVAQRDLRS"
     gene            complement(34010..34864)
                     /locus_tag="PK063_03245"
     CDS             complement(34010..34864)
                     /locus_tag="PK063_03245"
                     /inference="COORDINATES: protein motif:HMM:NF012791.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016208 - AMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HMZ96085.1"
                     /translation="MNAPRNPLSIHRIFHPTDFSQDSQVAFVHALKLALVFRAELTIM
                     HVDPDVSPEGFEDFPRIRPTLAQWGLLPESSSKSDVTTLGIRIRKVRALAADAKQAIM
                     HHLTATPTDLMVLATHKHEGFAGWIHHAVAEPVSREMHVTTLFVPSNVAGFVSRTTGE
                     TSLHRVLLPISSHPPSQPAIDAATVLVSQLSKPPVTMTLIHAGAEADVETLALPQKAD
                     WSWNQLFGKGDPVEWILAAGAEFDVDVIVMATKGQDSLLDMLRGSTTERVLRGARCPL
                     LAIPAPLI"
     gene            complement(34927..35322)
                     /locus_tag="PK063_03250"
     CDS             complement(34927..35322)
                     /locus_tag="PK063_03250"
                     /inference="COORDINATES: protein motif:HMM:NF022666.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3015 family protein"
                     /protein_id="HMZ96086.1"
                     /translation="MTGHRRSLIAAASGLSLLALLSACSFKATFKETTDTTSNITGTT
                     SGRIWWNEDGLLKSEHKVAAFTAYNADNLEADAARGHGEYLASLDALAHLPDAAVFQP
                     TAQAAFSRWSQAGSSSATELVKALQTAHR"
     gene            35575..36015
                     /locus_tag="PK063_03255"
     CDS             35575..36015
                     /locus_tag="PK063_03255"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96087.1"
                     /translation="MKVGMGLCVIAGILCAAPLVRAETVPLKPGEYQVTAVTESSSGE
                     AGKPDTHTRCVKEEHLANPDAVFNYYALNGFKPNPANKVMNVSMHGGTVSYDIEGLYA
                     MTRVEGTVSTTGFSVVRKATPKGDKALSVTMKVDGKRTGDCATK"
     gene            complement(36097..38340)
                     /locus_tag="PK063_03260"
     CDS             complement(36097..38340)
                     /locus_tag="PK063_03260"
                     /inference="COORDINATES: protein motif:HMM:NF021597.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2330 domain-containing protein"
                     /protein_id="HMZ96088.1"
                     /translation="MEQQHANPEPDPSASRQDPRYYQIASLGTLLIYGLCWLHFDLSI
                     RQIVVTIGTALLTQYVGTILVNLPAFDAKSALISSLSLCLLLRTDDLAVAALAAFLAI
                     GSKFVLRWHDKHLFNPTNLALTVMLGSGLGWISPGQWGQTAWLAFLIACLGSLVVTRA
                     ARADVTLAFLACYVGLLFARAVRLGDPLTIPLHQIESGTLLIFAFFMISDPKTTPDSR
                     IGRMVYALLVSFTALYVQFGLFKPNGPLWGLIACAPLVPVIDHVLPGSRYQWAHASTG
                     GSPHPAPIPVRTLSTVLSSTKEVSMRRAIIPSVLFTLSLLAWGGDALAFCGFYVGKAD
                     TKLFNKASEVAIARHDDKTVITMANDFKGEVKEFALVVPVPTVLEKEQIHVGDPALLK
                     HLADYSAPRLVEYFDQNPCLRYELMERRSMDAMKSVAPSAAPPERDKALGVTVEAQYT
                     VGEYDILILSGKESSGLEIWLTENGYRIPQGASAVLQSYLKQGMKFFVAKVNLGEQAK
                     LGLTYLRPLQIAFESPKFMLPIRLGTVNADGAQELFLYFLTKQGRVETTNYRTVRLPE
                     AQEVPLFVKEKFGDFYRDLFSQQVKRESERGIFMEYAWDMNWCDPCAADPLSAEELRS
                     LGVFWQESSGRMGKSLPMAQNVFLTRLHVRYDAAHFPEDLMFQETSDRGNYQARYILR
                     HPWTGTEDCAAATAYRQQLRERYEQEAQTLASLTGWNIGEIRHTMKLASLPAGKEKKW
                     YQRLWDN"
     gene            38486..39118
                     /locus_tag="PK063_03265"
     CDS             38486..39118
                     /locus_tag="PK063_03265"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96089.1"
                     /translation="MPIQVIVLIGFLSLLPGCSLEQELSRTPRTAVEQVLLTQAVNQA
                     LTNLTVQLPVGVNVELDATGLESDRSRLRMTNSDLGSLNSPNRDILYIRDTVAAELGR
                     RGYLVRARDTESPYLVRVMAESFGTMQGITFFGMPPVQSVLIPFALPELTLYKQQNQS
                     GYARLHLDIYDNRTGEFLGSSATLVGRTFYNQYTMLFFLTWNRTDIDAPP"
     gene            39167..39529
                     /locus_tag="PK063_03270"
     CDS             39167..39529
                     /locus_tag="PK063_03270"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96090.1"
                     /translation="MLELLLVLASLVVIGLTGLLTVVATPPRMVELGLWALALGLLIG
                     IPTGWWYHVVLYRALSARMALPRRWWQRPVELHPLLQPDEFRRVRPWFVAGALGFVLC
                     FTGGVAAIAGMLVMRFYP"
     gene            complement(39554..40861)
                     /locus_tag="PK063_03275"
     CDS             complement(39554..40861)
                     /locus_tag="PK063_03275"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96091.1"
                     /translation="MADHELEHLLGGFAANTLTPEERKQLYAAALHDQQLFTALADEQ
                     ALKELLANPDVRRRLLQALQHTSPTATGGTDTWWGWLKKPAGLAWAGGLAAAVFAIAF
                     GTRIYQESLDRARQSIVTEEVKPAAPPMPRVQPSMPAPQSAATPDPQAMEPADAAKEN
                     RRTDTRAKREQPLAGRASEQSAAKSSTDTAPPRRERDESSNNAPMAAAEKKSTGTPPS
                     ADRTLAAPAPPSTAPQPSAAPPLLQAPAGFSAAGAPAPKKSARALFYGEQSSPSLGQA
                     KPLGLRYSFVTRGTDGRTQEITAAMVARSSDPVRLTVEATQESYVQLLQNLGSAGTRL
                     WWPPQETGKISLKLQPGKRTDIPIPPPAENGLVTLIIRLSSKPFGPLTMQEVGMLDRF
                     SASLLIEAVSPGTTAGVQEQATYVVSQDPSTSAQLAVEIPVVQ"
     gene            complement(40910..41407)
                     /locus_tag="PK063_03280"
     CDS             complement(40910..41407)
                     /locus_tag="PK063_03280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HMZ96092.1"
                     /translation="MTRDEILTHLRERILTFATSRLQKDVAEDLTQEVLMLLHEKYVR
                     VTELTELVPLAFQVLRFKMLDAHRKSLRRGEYNDHSVDDLPSADPGTDPASQLDQKQR
                     VDRLMAALGQLGDRCRQLFKWKLEGNSFPEIQTLMGQASINTIYTWDLRCRKQLLSLM
                     GGTWE"
     gene            complement(41419..42411)
                     /locus_tag="PK063_03285"
     CDS             complement(41419..42411)
                     /locus_tag="PK063_03285"
                     /inference="COORDINATES: protein motif:HMM:NF016777.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HMZ96093.1"
                     /translation="MTRPVTKTLIDCHVHLAALPDGDNGCYISPKTLRSPLFRFLLWK
                     HGLSPKHPREANQKYLADLLTELRASRHVHKAVLLGMDGAYDQNGRLNQANTDFLIGN
                     DYVLKTAQAHPDELLAGVSINPQRRDAIEEVHRCADAGAVLVKVLANAQQFDPANKTY
                     TPFYRALAERKLPFLSHVGYEFSLIGKDQSVGEPDRLRVALDEGVTVIAAHACSYGLI
                     LYEKFLPTLHDLVQRYPHFYADISALTLPNRLRMLLHLRNYPQVHERLLFGTDYPLPV
                     FHLAAWGRVAMGRLRQLILTKNRFDRQVDVCQGLQVGFRSIGDLIPHASGQTPH"
     gene            complement(42474..45872)
                     /locus_tag="PK063_03290"
     CDS             complement(42474..45872)
                     /locus_tag="PK063_03290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[ACP]--phospholipid O-acyltransferase"
                     /protein_id="HMZ96094.1"
                     /translation="MRGLLVAQFCGAFNDNAWKFMVALLGIRAVTTTLAPGQDLEAAS
                     QTQTTLAMVVFTLPLVLTSFVAGFFADRLSKRTVIITMKAVEVLLMAGATLALLSHPT
                     GGAWALVMLACMGVHSALFSPAKYGILPELLPHAQLARGNSILELFTFLAILTGTTAG
                     GFLLAGAGNQPWLAPLALTILALIGFAAARAVPPVPAARAAGGLFDTLRGALSALRAD
                     RLLRLAITGAVFFWTIASLVVQNVLVYAKAVLGLSDALATVPSALISVGIGLGALVVG
                     RLSRSRVEYGLVPLGAAGVATFLLTLGWWVPAFTGTLVVMIALGMSSALIFIPINALV
                     QWRAPHDRRGSVIALENICVFTGILLGSLSGGVLANVGLSTVGIFLATAGLTTIGTAW
                     AMWLMPETFLRLVLVLLTHTIYRLRIVDQTHVPVTGGALLVPNHISFIDGFLLIASVD
                     RPIRFVVDAHYVNLPFFKPFMRALNVIPIASDGGPRVILRALRDAGQALDHGDLVCIF
                     PEGQITRTGNLLPFRRGFERIVKGREVPVVPVHLDRVWGSIFSFVGGRFVTKWPERLP
                     YPVTVSFGAPVPAGTPAHELRRLVRELGETAWHWRKSSRRPLHAAFVRAMRRHPFRLA
                     MADATKPHVSSLQALIGAIALARALTPHWQGQPSVGLLLPPTVAGALTTVAAALAGRS
                     SVNLNYTVGKAGLESAVRQAQLRTIVTSRKFIEKAKLEVPDGPTILWLEDIGATIGSL
                     QKMLAAALALFAPLRLIESSCGQTRRVTMDDLATIIFSSGSTGEPKGVMLTHFSIDAN
                     VQAVSQVLPLDPEDRILGILPLFHSFGYLVFWYVTLNGAASVFHPSPLDVTAVGELCA
                     KYRLTFLVCTPTFLQLYQRRCTPEQFSTLRVVLTGAEKLPLRLCQSFQDRFGIGPIEG
                     YGVTECAPVIAVNCPDFRAAGFFQPASRRGTVGQPLPGVSVRIVDPETDAILPPGMPG
                     MLLVKGPNVMNGYLGREDLTAQAMRDGWYITGDIATLDDDGFLTITDRLSRFSKIGGE
                     MVPHRLVEDALQQASGEELQVCAVTGVPDERKGEQLAVLHTLAEERIPHILAKAQAAG
                     LPNLFLPSHSRCFKVEALPILGTGKLDLRALKRMAMERLNISGT"
     gene            complement(46001..47884)
                     /locus_tag="PK063_03295"
     CDS             complement(46001..47884)
                     /locus_tag="PK063_03295"
                     /inference="COORDINATES: protein motif:HMM:NF012700.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MutS family DNA mismatch repair protein"
                     /protein_id="HMZ96095.1"
                     /translation="MNPVTSAELKPSREQHLVHALRRAVHLETNGRRVSARFTTARLT
                     IFAATLLGSIIPHKLGWTLFGNLVLASGFVLFLIVAWYHNRLEDRLHRLRRWQGIKRV
                     HLARLSLQWAEIPLRDVTVPERHGYARDLDLTGPRSLLHLIDHSISSQGRQRLASWFL
                     DQPPLAAPWSSRQALIRELTPLSLLRDRLVLEAQAVEEADIDGRRLLAVLQKRVDDSG
                     LMPMLLTESALAVTTAILLLADLISGLGNYWMLSFGLYAFLFLSVRSRSEEIFDHAQS
                     LHLQLERLSAVLQYLERRSYRSTPHLAKLCAPLMQQDSSPSRSLKQAASLMNRLSVRA
                     HPLVHYLINAVGPWDLFHTYRLQQLQDRIASVAPLWFELLADLDAAASLATFAHLHPN
                     YLWPTLHHAGADGQENGNAPELAAEGLAHPLIPAAVRVANQVTLQGRGRIFLVTGSNM
                     SGKSTFLRTIGINTCLAQAGAPVCATAFRWSLVRIGSCIRVDDSLDGGLSFFYAEVKR
                     LKTILDSTRDRQGPPVLWLIDEVFKGTNNRERLIGGKALITALAGGNGFGLVTTHDLE
                     LAELEKQLPTVTNVHFQETVVAGALHFDYRLKPGPCPTTNALRIMALEGLPVESADPM
                     PPR"
     gene            47914..48849
                     /locus_tag="PK063_03300"
     CDS             47914..48849
                     /locus_tag="PK063_03300"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF018076.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HMZ96096.1"
                     /translation="MTSTSKVDQSSSSDSAAVQTGDWIQVDVRTSLDAGELLGMLNDP
                     DVTGAWQEGDEVHLYWPAGRCGPDTWQGLKRALTQLGHPDPDHAVTINHLANQDWNAQ
                     WSRLVEPIKIGRVLIRPSWRTVSLNSDEIELIIDPKQAFGTGHHATTQLLIEWLQQAV
                     RPDDRVLDVGTGSGILAMVALRLGATEALGVDFDAVAVDCAREYAQVNGFDTRLTLAV
                     GQAQAPQAHDAFDPTLVLANLDRQTLLTSADSLCAYAVRGARLFLSGLLAEQRSEIEA
                     AYATRGVYMKAVRERDGWLALEATAMETCEGGLCS"
     gene            48857..49348
                     /locus_tag="PK063_03305"
     CDS             48857..49348
                     /locus_tag="PK063_03305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HMZ96097.1"
                     /translation="MTRSATPYVHQISVSDGGVPKLAVPSARITIDGLAGDRQRNRKY
                     HGGKDRAVCLFSLERIEALRAEGHTIGPGSSGENLTVAGLDWQHMAPGDQLTIGEHVR
                     LELTSYTTPCRLNAPWFKDEDFRRIAQEVHPGWSRLYARVLNEGVVKPGDVVVVDACP
                     GER"
     gene            49376..50038
                     /locus_tag="PK063_03310"
     CDS             49376..50038
                     /locus_tag="PK063_03310"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HMZ96098.1"
                     /translation="MMKRVLEPELMDDVAQALAYAKADFAEENQSFVDRFREYFPAWD
                     GGHVVDLGCGPGDIPIRFLRAYPHARVTAVDASRPMLDLAADAIAGAGLTDHITLRCE
                     RFQSLVLPEQADALLSNSLLHHVPNPLQFWFRLKQLAKPGACILVMDLLRPDSPESAQ
                     ALVEQYAADEDPILKRDFYHSLLAAFTEDDVAAQLAEMNLSRLLIDVPDDRHWVVGGI
                     IP"
     gene            50089..50973
                     /locus_tag="PK063_03315"
     CDS             50089..50973
                     /locus_tag="PK063_03315"
                     /inference="COORDINATES: protein motif:HMM:NF015722.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HMZ96099.1"
                     /translation="MSGVCPARSIFIATLRCVHSALLGCLLAMALLYPAESTAGILEQ
                     LRKPRPSSELQVHSDVPMIMIPEGVFRMGADGTDALEDEKPQHDVWLSRFEIDRHEVT
                     TGHYAEFLAATKRPAPWQWESLDLSQHGDRPVIGVSWFDADAYCRWRGTRLPTEAEWE
                     KAARGTDGRLFPWGNHSPQEETANFGLGARFSYSQVLAPVERYEQGRSPFGLYQMAGN
                     AGEWVADWYGAHYYENGPRQNPSGPDAGAFRVVRGGSWSDLPKYLLTYGRFKLPPETR
                     NSYTGFRCARDGGVLASP"
     gene            complement(51016..52809)
                     /locus_tag="PK063_03320"
     CDS             complement(51016..52809)
                     /locus_tag="PK063_03320"
                     /inference="COORDINATES: protein motif:HMM:NF012271.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin type III domain-containing protein"
                     /protein_id="HMZ96100.1"
                     /translation="MKTPKSVLVIGVAGCLSSALCSTALPPTAAAADTTLSLLQQSST
                     DAVAIMAQNSGTAPIFTSPTALVLSAQKGQTAVGTLNLKKSSTDQHSYYLSTNQGWVW
                     MNPPYGSTQTITTETDQLVITAQTANLAAGTHSAVVYIVDSGPNNFTNMLRIPVTLTV
                     TATAVTPPPPPPPAAVPPAIIPTPSPVAVPPPPAPTPVVAPVVTGTAITSSPAALALS
                     AVKGQTAVGTLSLRKGGTDQHSYYLSTNQGWVWMNPPYGSTQTITTETDQLVITAQTA
                     NLAAGTYSAVVYVVQSGPNNFQNMLRIPVTLTVTASAVAPPPPPPAAVPPAIVPTPKP
                     VVLAPPPPPAPAVVPPPPAPAPPAPAPVTVATGPIQVTPSSLSLTSANNVGTLTLRKT
                     GTDQHAYYLSTNQGWIWMNPPYGSTQTITTESDQLVITAQTAGLAAGTYSGVVYIVES
                     GPNNFANTLRIPVTFTVAAGQTASSTPTTPTQPTVASPPPPPPSPPSPVPVTTTPTPT
                     SSASSTAPKTASATVSWNANTESDLAGYRIYVGTKSGSYGVVGPFEVTNGTSFTVPNL
                     PLGATYFFAVSAFDKSGNESAKSAEVSKSLF"
     gene            complement(53070..53909)
                     /locus_tag="PK063_03325"
     CDS             complement(53070..53909)
                     /locus_tag="PK063_03325"
                     /inference="COORDINATES: protein motif:HMM:NF024109.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HMZ96101.1"
                     /translation="MKERRNNRHHFTTMEEALSFHDQAGHRIAAVLATPPQSTDSVAV
                     LCHGFLSHKNSTSNQALAELLKTRGIATLRFDCFGHGDSDGPFAKLTTTIGVAQARAA
                     LTYAMTRGYRRLALVGSSFGGLVSLLAASEWTDLHNSAPEDVPPLACLALKCPVVDFG
                     EELRLELGEDGLQEWQRTNTIPDLHGGPSRLPLDYAFYQDCLNRIAYEPARAIAAPTL
                     IIQGDHDEYVPLHQSQRLYASLAGPKHLEILPGADHRFTNPSDFQLMLTLLTDWIAAP
                     PAA"
     gene            complement(53890..55179)
                     /locus_tag="PK063_03330"
     CDS             complement(53890..55179)
                     /locus_tag="PK063_03330"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96102.1"
                     /translation="MSRGLGSPLSFLLAGWGWVLLTALLGLAAFGGIVRGGPLPSGLR
                     LLHVHGVLIGGVLQLMTGLAIAAHDLSGHEGKRTTHRLLLLSMNLTAVGFAAGAWFRN
                     PTLTLAAGFLLAALFVPMARHMLTALRTCSGWTPLVHVYFGISFAGLFGSMVLGGLLA
                     DAWYPTWHGILRLGHLHAGLLLFLILGAVGTIQLTLPMMVHRPLHSPGMGQAVMLLLP
                     ASAAGLITGFVLSSVHIQLAAGTVLLIALALCCINLLRTWSQAGQPGSAATDHLLTAL
                     SFLLIMTFIGLAFGINVLSTPPAMPYGTLHLVAYTHTAFLGFLLQSMVGGLSFTLPSL
                     LATSRIANQKKRGTYREDLERIMNRWRAAQVATVSFGSLGLVLVASLTWNLPLSSPWL
                     QTSTWISLGLLLFHFTMVTVKLAQATGAQPSHEGAAK"
     gene            complement(55185..55979)
                     /gene="thiD"
                     /locus_tag="PK063_03335"
     CDS             complement(55185..55979)
                     /gene="thiD"
                     /locus_tag="PK063_03335"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HMZ96103.1"
                     /translation="MIKQVLSIAGSDSGGGAGIQADLKAMSANGVYAMSVITAITAQN
                     TEEVADVFELPTSIIAAQLDAIFDDFDVAAVKTGMLSSAEIIRTVVKLLKPQQVKHLV
                     VDPVMIAKGGQALLKPDAIDTLKSALFPLALLVTPNVHEAQQLSGIEITSLADARRAA
                     KVIHQFGCANVLIKGGHLQKERGTDLLYDGRFFNIFKGEYIDTPHTHGTGCTFASAIA
                     AHLARGKSVSDAVQTAKTYLTEAIRHGLAIGHGKGPTNHFYFLNQG"
     gene            complement(56014..56988)
                     /locus_tag="PK063_03340"
     CDS             complement(56014..56988)
                     /locus_tag="PK063_03340"
                     /inference="COORDINATES: protein motif:HMM:NF036774.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FlgO family outer membrane protein"
                     /protein_id="HMZ96104.1"
                     /translation="MIRLLPCLILLVLCHSTSLAASKYEDSVKELAEGVAAEAIKMKK
                     SRLALLDFVDSKGDVTPIGQFLAEELATHLLVAGELKVVDRKLLIATMEKHQLTHLDT
                     SQAKAAKKVAKALRADLYVTGAYLEIPEGIQVTAKLIGPYTVYPVGASRTIVPKSGPL
                     AALLKQAAAPAPATAAVVTDSAPVLSAHENDLYKFTILSVTRQDDLIGLDLVFTNRTA
                     HPVKIGCQLLDTYLVDEHGEQWKQNVAQNREGLCTRGMELNPKRQQRASLSFLATNKP
                     PTGPITLHYHETSPRADRIITLDGLKIASAPVVEPGAPAAQESTPPTP"
     gene            complement(57064..57564)
                     /locus_tag="PK063_03345"
     CDS             complement(57064..57564)
                     /locus_tag="PK063_03345"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96105.1"
                     /translation="MTDIPRQTSPRLRMMARLGVWISLLGGLLLPWIIMLTVEILVRD
                     IPYPRAWRSFTLHLFAPGYNFFFVGVLTALPFVILALIILFHLGTAPANNALIAYRRA
                     LGLFSAGLSMALIAAWVHVDVLIHPDAQGALAYFYLPILLLMMLPFGYGLGRALAKIF
                     LPRLSG"
     gene            complement(57561..58607)
                     /locus_tag="PK063_03350"
     CDS             complement(57561..58607)
                     /locus_tag="PK063_03350"
                     /inference="COORDINATES: protein motif:HMM:NF025030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HMZ96106.1"
                     /translation="MTDAASTPTVLSSREIQLHLLGLVLLLGVLGLWYWFSTGARVVP
                     TLIELLKDDDPSTRIVAAEQLGQVGPAARSAVPQLLSQATQDGSQHANTTAATALKWI
                     DLTAARRVMTHFVPRLQDPDVQLRRTACAVIGSLGPIAKPAVPALLAVTHDADALIRR
                     NALIALASIGIPSLPIAAALVDGLRDSSSLVRQTAVAQFAFTVPPSPDAVAVLTPMLN
                     DPDKGIATLARTALDKPRAGDAAHIESLGMMLGHSSARDYALHQLAQLGPAAHDALPP
                     VLALLEDEQPLIRYLAAESIGGMGAVAKQALPALQRHQDSDLVVRAAIAEAVSAIEAG
                     AVVNAEPLSKELPR"
     gene            58858..59016
                     /locus_tag="PK063_03355"
     CDS             58858..59016
                     /locus_tag="PK063_03355"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96107.1"
                     /translation="MPVYFLIALTILFCAIAIWASVTQESIPMRGEEEPDWDVEPLNQ
                     SQEYRKTG"
     gene            complement(59307..60035)
                     /locus_tag="PK063_03360"
     CDS             complement(59307..60035)
                     /locus_tag="PK063_03360"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96108.1"
                     /translation="MPPHEEGKRKISFPNSNVSGGNIVVVLIENGKSPDQPYNARLGF
                     WLPPDSPYGNFQLKLRKLCERLDEANRRLIDTFDYWNQAMEQKTSVNLFQRHEYAIEQ
                     AVYLMRRVADELIAMIWCLHEWEKTGDYPRQIRIDCIGAALESTQQNLSKDLKVLFDP
                     HNPVMKALNEISNAFKHSFVHSDLTLIGRDEPCVYALGLAHNKLSSEMKFHNFSVSWL
                     VREFSAFYKSGMQWLASFSERHRK"
     gene            complement(60377..61045)
                     /gene="tenA"
                     /locus_tag="PK063_03365"
     CDS             complement(60377..61045)
                     /gene="tenA"
                     /locus_tag="PK063_03365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050334 - thiaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HMZ96109.1"
                     /translation="MSFSNHLRKLAQPVWDAQLTHPFVLALGKGTLSERKFRYYILQD
                     ALFLADLARVFAAGSLRAPDSESALRFAKLAEETITVERSLHENYGKRWNLSPQEMLN
                     EPMAPTNYAYTRHMLAVAQAGTATEIAVVALPCAWIYCVVGKHFLKNGAPPAKHPYRD
                     WLMLYASPEFEAVQEWMRARVDTWARTAGHEEKKRMEQAFLISSKYEWMFWEMAWNEE
                     KWPV"
     gene            complement(61158..62561)
                     /gene="sthA"
                     /locus_tag="PK063_03370"
     CDS             complement(61158..62561)
                     /gene="sthA"
                     /locus_tag="PK063_03370"
                     /EC_number="1.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003957 - NAD(P)+ transhydrogenase
                     (B-specific) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Si-specific NAD(P)(+) transhydrogenase"
                     /protein_id="HMZ96110.1"
                     /translation="MAHYDLLVIGTGPAGQKAAIQAAKLGKKAGIVERTRVVGGVCTN
                     TGTIPSKSLREAALYLSGFHQRSLYGASYRVKQDITMADLTFRSNHVINREIEIIQNQ
                     MTRNNIDLWYGTASFVDPHRVRVERADDHVEHTADFIVIACGTVPARPAHIPFDDQTI
                     IDTDGLLKLKDLPKSITIIGGGVIGAEYASILATMGLHVTLIERRPRLLEFVDQETIE
                     ALQYHMRSIGVVLRFNEEVVSVEPISKELVIVRLKSGKEIAASTVLYSVGRTGASATL
                     NLEAIGLAADERGRLTVNEHYQTSIPHIYAAGDIIGFPALASTSMQQGRHAACHAFGV
                     PYQTQSDLMPYGIYSIPEISMVGRNEDDLTKHGVPYAVGIARYREIARGQIIGDEIGM
                     LKLLFHNKTRQLLGVHAIGDGATELIHIGQTVMAFQGQIDYFIDAVFNYPTLAECYRV
                     AALDGINQLPRPWTPRA"
     gene            complement(62592..63278)
                     /gene="tpx"
                     /locus_tag="PK063_03375"
     CDS             complement(62592..63278)
                     /gene="tpx"
                     /locus_tag="PK063_03375"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HMZ96111.1"
                     /translation="MRSMSAPVLSGVLVPRLLAGLLCLGLSACGTLPGTGKGGFSYKD
                     MPIADGSAVAGEGNNILFQGKPLMLTGMGIKVGDKLRDVKLAQIDLSMIPINDTKGKG
                     KVRIISIVPSLDTKVCEQQTHYLSEKNMGLDRMVELITISIDTPFAQKRFAEEAKISN
                     VTFLSDFRAADFGKAHGLLLKDLHLLSRALLVVDKDNKVRYLQITPELAQLPDLEDAF
                     RFARKLVTAS"
     gene            complement(63346..64308)
                     /locus_tag="PK063_03380"
     CDS             complement(63346..64308)
                     /locus_tag="PK063_03380"
                     /inference="COORDINATES: protein motif:HMM:NF024109.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HMZ96112.1"
                     /translation="MPRPASLVRFVAPAPHHLATWFLASLLMSGCAARPDVPPWFDAI
                     QRLPVHTISVTGHRIAYLDEGEGPTLILLHGYGGSMWQWEYQQPLTKHFRVITPDLLG
                     SGLSEKPDIEYRPSALIESIRGLMDGLGLQTATVIGNSMGGGVAIGMALTYPERVDRL
                     VLIDTLPDHVRERLVSPLMQRAINTHVPAWMARFGASLFGSRTMEAVLKEVVYDHSLI
                     TPLVLERSNRNRQREDMIGPLLSLRDSLPLWEQLYAPRLTAIRQSTLILWGEHDRLFP
                     PQVGQDLQAMIPHSRLIVIPEAGHIPQWERPQAVNRHIMEFLQP"
     gene            complement(64312..>66042)
                     /locus_tag="PK063_03385"
     CDS             complement(64312..>66042)
                     /locus_tag="PK063_03385"
                     /inference="COORDINATES: protein motif:HMM:NF006761.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate/oxaloacetate carboxyltransferase"
                     /protein_id="HMZ96113.1"
                     /translation="VGFWSLEVWGGATFDTCLRFLKEDPWERLRALRAAMPKTKLQML
                     LRGQNLVGYRHYADDVLDKFIERSAANGIDVFRIFDALNDVRNLERAIREVKACEKHV
                     EAAISYTTSPVHRLDGFVTMGKRLEDLGADTICIKDMAGLLAPVDAYRLVKSLKAAVR
                     VPIHLHSHYTSGMGTMTALMAVMAGLDLLDTSISPLAGGASHPPTESMVAALRGTPYD
                     SQLDLEDLQPIAEHFRTVRRKYRQFESDFTGVDAEILTSQIPGGMLSNLAAQLAEQNA
                     LDRMKEVMDEIPRVRKDMGYPPLVTPTSQIVGTQATLNVLTGEQGERYKVITTETKNY
                     FLGLYGRAPGPLDKEIMARAIGDEEPVKGRPADRLEAEFEKLKKDMPESATTLEDQLS
                     FALFPAIARDFFEAREQGALQPEPLEPTDTKGPAVAHDLHLAPAEFNITVHGENYHVV
                     VSGSGRTTDGRKPYYIRVNDRLQEVSLEPLQEVLAGVPESPEASSTSKPKRPRPTKPG
                     DVAPPMPGRVVKVLVTDGAQVKTGDPLLIIEAMKMESQVPAPMDGRVAAILVAEGDNV
                     KIDETVIQLE"
     assembly_gap    66043..66142
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(66259..67677)
                     /gene="accC"
                     /locus_tag="PK063_03390"
     CDS             complement(66259..67677)
                     /gene="accC"
                     /locus_tag="PK063_03390"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HMZ96114.1"
                     /translation="MFRKILIANRGEIAMRIIRGCRELNIATAAIYSEADSSGIYVKK
                     ADESYLVGPGPVKGFLDGKQIVEIAKRIGADAIHPGYGFLSENAKFARLCHASGITFI
                     GPSPETIDLMGSKVKARQIAQQAGLPIVPGTEGGVTSIEEALEFVHRINYPVMIKASA
                     GGGGRGLRVVRSDQELRENMEVAAREALAAFGDGSIFIEKYIERPHHIEFQILGDKHG
                     NIIHLGERDCSIQRRHQKLIEIAPSLVLTAKLRAQMGEAAIAIAKAVKYDNAGTVEFL
                     LDHEGHFYFMEMNPRLQVEHTVTEQITAIDIVRNQISIAAGKPLEIRQKDVTLQGHAI
                     QCRINAEDPRNNFMPCTGTVTAYLSPGGIGVRIDGAVYRDYTIPPYYDALLAKLTVRG
                     RTWEEAVSRMRRSLEEYVLRGVKTTIPFMKNVMMEQDFQAGRFDTSYLETHPDLYQYE
                     ESEEPEDLVLAISAAIAAYEGL"
     gene            complement(67850..68305)
                     /locus_tag="PK063_03395"
     CDS             complement(67850..68305)
                     /locus_tag="PK063_03395"
                     /inference="COORDINATES: protein motif:HMM:NF013955.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IPT/TIG domain-containing protein"
                     /protein_id="HMZ96115.1"
                     /translation="MRTFMTVALGSVVALGVLCMAVPSGQAQEGAMVEGAGYTMFNTE
                     SIKGSDTNKLEKDPVCDRSKRPSIGKVEPDEAKPGDKIVIKGENFGSKECFHGVTFSA
                     APKDKIEYQFVNESTIEAVVPDAKAGMSFIIVVAGGGSAQSKPLLIQAK"
     gene            complement(68318..69229)
                     /locus_tag="PK063_03400"
     CDS             complement(68318..69229)
                     /locus_tag="PK063_03400"
                     /inference="COORDINATES: protein motif:HMM:NF024257.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HMZ96116.1"
                     /translation="MSGRDCRPGLPRHDAHRKAAQGREGESFSMYSRISALLCAGLFS
                     LSTLPASAEVAGSMVIAGHGPEQHVMESLAHAFEKANPRAYIDVVWDDNSKPLDMVKA
                     KQAHIAVTGASANGLHSVQIAWDGIAIMVHRSNFTKEVTKQEVADLFSGKYKVWADLG
                     GPDTKVLLIDRPRNENNRDAFEQLLGITGKIPDSTKVIAKDEKVIKTIAGTLPPNSAV
                     TYLSLGQALEAVASGVPVRLLPVDKVEPETPTVKDGRYSLRRPILLISNNDADPLVAA
                     FEQFALSDEGQKIISDSYTPLPKTSSP"
     gene            complement(69241..69552)
                     /locus_tag="PK063_03405"
     CDS             complement(69241..69552)
                     /locus_tag="PK063_03405"
                     /inference="COORDINATES: protein motif:HMM:TIGR02605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HMZ96117.1"
                     /translation="MPVYEYRCDQCTHRFEATQSIHARPDDTVCPQCTHMGATRILSA
                     FASKVKGSHKPGFEEIKAYDMLHERMDRFSKLPPAMGKRVDVTPDMMSGAVTPTDSPE
                     S"
     gene            69722..69898
                     /locus_tag="PK063_03410"
     CDS             69722..69898
                     /locus_tag="PK063_03410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96118.1"
                     /translation="MPLLIRKYKGNGGVMQEERIDDPDRIVRYMRLFEEKDVKKLETG
                     AKTVIEKDEWQLLP"
     gene            70048..70251
                     /locus_tag="PK063_03415"
     CDS             70048..70251
                     /locus_tag="PK063_03415"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96119.1"
                     /translation="MIYWIHIARAIDRVTLHRDRCSEVPSSISSSDFWEGGWFDYPDK
                     ERALAAMEQAGTTDERKCALCKP"
     gene            70346..71224
                     /locus_tag="PK063_03420"
     CDS             70346..71224
                     /locus_tag="PK063_03420"
                     /inference="COORDINATES: protein motif:HMM:NF013088.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HMZ96120.1"
                     /translation="MPQLALLLTTFVWGATFPATKAALEQITPLAFLFLRFLLGMLLV
                     FAVLLLLRRKLTRDAAMLRMSLIASLWLFLGYVLQTVGLHLTTASNSAFITVLYVVFV
                     PLYLRRLSAHTWISNGIALIGLWFLVKPTASANLGDLLTLGSAAAFAAHMVCLERYTR
                     TTDAVSLFAWQLVMMTVAMLGAMWWEQPTAAMFEPSRVLLLGLGVTGILATGAFAVQM
                     WAQQLLPAQQVALLFAVEPAIAAWLAWYFLGENLDAQGWFGSAMILGGVLLGSRVPGE
                     MPQVSPTPVVVRSEGR"
     gene            71226..71696
                     /locus_tag="PK063_03425"
     CDS             71226..71696
                     /locus_tag="PK063_03425"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96121.1"
                     /translation="MAQKFGNSRWVQEGFLDNRQDGTVVGRITFAVLGAIDFYLTGNC
                     RGEISGKVIRFKNSRFADEDLAGQVLGDVESPQIGDASLISFDPHPHLVPHPYIEWFS
                     MRKNHYRIELVPEDAWIATEAEIAEIDAASRDIRDRLAPQYGSKSRSADESEWV"
     gene            complement(71744..72760)
                     /locus_tag="PK063_03430"
     CDS             complement(71744..72760)
                     /locus_tag="PK063_03430"
                     /EC_number="1.14.19.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016717 - oxidoreductase activity, acting
                     on paired donors, with oxidation of a pair of donors
                     resulting in the reduction of molecular oxygen to two
                     molecules of water [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA desaturase"
                     /protein_id="HMZ96122.1"
                     /translation="MSSDLHPLTLPDNGELSKTAEQPAEQATSPTPWLTILHWFDSWA
                     GIENMKTDAAPATVDWLRAIPLITVHLICLGVFIVGWSWVALGVCAAFYFIRMFAITG
                     WYHRYFSHRTFKTSRACQFAFALLGSSCAQRGPLWWAGHHRHHHIYSDKPEDTHSVRQ
                     GGFLWAHIGWISSKKFFPPRLKSIGDFAKFPELRFLDRFDTLVPTICGFGMFGLGKLL
                     ESYAPGLGTNGPQMLIWGFFVSTVALLHGTCTINSLSHVYGSQRYKTGDDSKNNFILA
                     MITLGEGWHNNHHYYAASTRQGFYWWEIDITYYMLRAMQAVGLVWDIREVPAHVREGK
                     NKLA"
     gene            73135..74160
                     /gene="hemE"
                     /locus_tag="PK063_03435"
     CDS             73135..74160
                     /gene="hemE"
                     /locus_tag="PK063_03435"
                     /EC_number="4.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004853 - uroporphyrinogen decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HMZ96123.1"
                     /translation="MNDRFLKACRREPVDCTPVWFMRQAGRYMIEYRRLREKHSILDL
                     CKTPELAAQVTLQPIDRFALDAAIIFADILLPLEPMGLSLEFAEGEGPIIHNPLRDRA
                     AVERLKMLDDSDLQYVMDAISLTRKMLAGRVPLIGFAGAPFTLASYAIEGGSSRNYIH
                     TKQMMYGEPEVWHRLMDKFARAITGYLRRQIKAGAQAVQLFDSWVGCLSAGDYAEYVM
                     PHVQLIFDGLKHEGVPLIHFGTGTTAILKSMRQAGGDVIGVDWRIPIDEAWAMVGYDR
                     AVQGNLDPVTLFGPMHEIERRVTDILRRAGGRPGHIFNLGHGILPNTPVEHVAATIDL
                     VHKLSAR"
     gene            74246..75190
                     /gene="hemH"
                     /locus_tag="PK063_03440"
     CDS             74246..75190
                     /gene="hemH"
                     /locus_tag="PK063_03440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HMZ96124.1"
                     /translation="MSAAPRPIALLLMAMGGPDSLENVEPYLLDVRGGRPTPPELVEE
                     IRTRYRVTGGKSPVLDITCEVAAALEQRLNASGERRFRCYVGLRHWHPFIRDTYAELL
                     KADPDHIVGLCMAPQYSSLSIGAYVKKVEEARAELADETPISFVKSWHRHPLLIAAIV
                     AHIRHTLERFPVEVRAQVSVLFTAHSLPERVVAMKDSYPEEVGATVQAVCAQLGGQPT
                     RFAYQSQGRSGEKWLGPSVEETLEDLAQAGHHHVLVAPIGFLCDHVETLYDIDIELTQ
                     LARTKGIQLERIPMLNASAPLIDILTSVVETHESSLVH"
     gene            75202..76671
                     /gene="hemG"
                     /locus_tag="PK063_03445"
     CDS             75202..76671
                     /gene="hemG"
                     /locus_tag="PK063_03445"
                     /EC_number="1.3.3.4"
                     /inference="COORDINATES: protein motif:HMM:TIGR00562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004729 - oxygen-dependent
                     protoporphyrinogen oxidase activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protoporphyrinogen oxidase"
                     /protein_id="HMZ96125.1"
                     /translation="MARTSRSVVIIGGGISGLSTAFALLEQAAAADVPLSCTILDAAP
                     VWGGKIVTHRVGRLVMEAGPDSFLSQKPWAMDLCRRLEIADELINTNPVEKKASVLRG
                     GQLHELPEGLVTFTPTQLGPFFRSGLLSWVDLARMGCDVLIPPRRSTEDESLASFFRR
                     RFGQHACERVMEPLMAGIYAGDAEQMSLRATFPRFYELEQTHGSVIRGMMAARRARAQ
                     KASDGRPRHTMFVTLKNGLADLVAGLTTRIRETGGVLKSGVQAEALRVRSHQAGRWMY
                     DVICTDGTALSAEALVLATPAYVSADLVRPLSPLAAGLMETIPYASTATISLIYPAAA
                     VGTRLQGFGFVVPRVEGRDLIAATWTSIKWPHRAPPEEVSVRCYLGGVGREAILQQDD
                     EALVRCVREELASIVGLQATPHYVEVNRWHRAMPQYTLGHLDRLTQLDAALSRFGGLA
                     VTGAGYRGVGLPDCIRDGAEAAAQTLRYLQTASKREAES"
     gene            76700..>77013
                     /locus_tag="PK063_03450"
     CDS             76700..>77013
                     /locus_tag="PK063_03450"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96126.1"
                     /translation="MLNDQLVISSVAGPFREPREPVFSYDYSIQRATWAATHAVRVKI
                     ALAEELDYVKTKLLGTVTGSPGQQLMLNKLLSRKIGDQKLRIAEEEGWLKERADVLVP
                     PFT"
BASE COUNT        15127 a        21434 c        24365 g        15987 t
ORIGIN      
        1 cgaccgtcgt tgccctcatc cttcgtccgg ttttttctcc acccgcaagt cctcagcatc
       61 gccagtacgt atctcgggct gcaggttcgt ctgaactata ccgatgtctg gcataacatc
      121 cccgtccgcg agggcgaacc gcccatctcc gccgaattct ggcatcgcga tcatgaggat
      181 aagcgggtca tcaagctgtt tgtgtttctg accgatgtcg acgagaccat gggtccgttc
      241 acctacgtaa gacgatcgca ggtggggggc gagttcggcc atgtctatcc cgccatccct
      301 cccattggtc gttatcccga gcaggatgcc ctgagtcaac tgatcaccgg caccccactg
      361 ccgtcggtgt cctgtgtcgg gccggccgga agtatcattt tgtgtgatac cagtggcctc
      421 catcgcggtg gccgatcggt gacgaaaccg agaatcgtcc tggtcggagt gtacacgtcc
      481 aacgccggga tggatgccgc acgctatgcc cttcctcgct ctctccccca cgaacacttg
      541 tcgccggccg caaagttcgc cctctattcg taacccgtca cgcctctgtg tcgaatccga
      601 ctacgggaac ccgagtattg acagagcggt gtgatggccg taggctcgcg cggtgcagtg
      661 tggatgattc atgacggacg aagaccgaat gaaggaggca tcagatggga gagcgaatac
      721 aggtgtccgg gcgggtggtg agatgtgtcg gcctccttgc tgcggcgttc gtcgccgccg
      781 gatggctggg agcggcgcag gcggcggatg aattgccgaa agagtcggtg ttgccggcag
      841 ccctcgccgg aaaggccgtg caggcggccc tcgacgcctg taaaaaggat ggctatcggg
      901 tcagcgcatc agtcgtagat cgtgccggtg tgcttcgggc catgctgcgg gctgatggtg
      961 ccggtcccca taccgtcgac agcagccgaa agaaggccta cacggcagcc agtttgcgcc
     1021 gtgcgaccag tgagttggcg gacatgatcg ccaagcagcc ggcgctgcag gcgttgcgag
     1081 aaatgaacga aagcattttg atggtgggag gcggtttgcc cattgaaatt gccggtgaag
     1141 tggtcggcgc gatcggggtc ggcggcgcgc cgggaacgca cctggatgat gcctgtgccg
     1201 aagccggtct tgatgccatc ggcgcagcct cgaagatgcc tgccgcgaaa tgaacctggt
     1261 gcagcgacga ggaccggcct tgttggtgat ggggctggtc ctcctcctgg cagcttgtaa
     1321 cagtgatcgt ccggaaccgg ctgaggcgga tgtgccctcg gcagggttgc gcttgcgggt
     1381 gacacgcgtt gccacacatc cctttttgtc ccgctaccgt ttaacgctgc aggtagaagg
     1441 atctcgcggc tgtaccgata cggcggagtt atttcctgat acgggatatg ccggcaggcg
     1501 caatgtgtat gcgcaggcgt cgggggcgat tactctgctg gggcagtatg atgcccgagt
     1561 gattgacccc gcgcagtgca gaattcgact ggtggagttt cagtcagtag gggagccatc
     1621 gaagttttta ggcgcgttcg atgtggatgc tgagaaacgt tggcaattta tccctgcctc
     1681 aatgaggccc gagcgcccgt tcgaaaagca ctaagtgatc ctcaagaagt cagccgctct
     1741 ttgaaggtca gttctgcgac tgccgactta tccaattcac cctttccgag cgtcaccagc
     1801 cggcggtatt gatcataggt ggccttcgca agcggaagtt ccagcccgac ttgttcggcc
     1861 aaactgcagg caatacccga atctttcgca gcatgggcgg cggaaaagta acaatcatgc
     1921 gcgcgctgct gcatgtcttc gccatccgtt tccagaacgc gggagttggc gccggtctga
     1981 gaaaagactt ctcgcagcat cgtcagatct aatcccaagg cggacgctaa tccgaggcct
     2041 tccgccaggg cggcggtatt ggcgttcatg accatgttca ccagcgcttt caccttggcg
     2101 gcgtccccgg cgggcccgat aaagcgcaag tgcgcgctca gatccttgag taacggggtt
     2161 gcgcgttcga acacgtcccg gcgcccgccg cacatgagat agagcgtgcc atggcgggcc
     2221 tggggaatac tgctcgccat gcaggcttcg aggctgtggc cgccctgttg ttccaccagc
     2281 ctgtgcactt ccatctgggc agcgggagag agcgttgcgc aattgataaa gagacggcca
     2341 gtcgcatgcc gtaacaaact gtccggcgta tttggcgcat agatgtggcg catggctgca
     2401 tcatccggga ccactgtcag gatcgtgttg gccagttcgg cgaccctggc gggagttgga
     2461 gcggccacac agccgagctc gttggcgagt gtttcggcgc gtgatgcctc ggtatcgtag
     2521 acggcgacaa gctgataggt gaggtcgtgg aggcgtcggg ccatgttggc tcccatgcgt
     2581 cctaccccga cgatgccgat acgaaactcc gcctgtgcca tccgcaacct cctggaaaac
     2641 atggtactct gactggtgtg gcagtgtacc acagtctatt caggccccgg tatcgcggca
     2701 tcggctgtga ggcccggggg cgctcggata acgacgaggg agtgtgtgat gcaacaatcg
     2761 attatcggat atcaccagga tgaggagggg cattgggtgg ccgacctgcg ctgcgggcac
     2821 ggccagcacg tgcgtcacca gccgccgatg acgagtcgtc cgtgggtact gaccgaagag
     2881 gggcggcagg tatttatcgg cactgaatta aattgcaaga agtgcgatga ggggggagat
     2941 gggttctcgc cggcagagcc gctttcgtaa gcgccgtgga gagaaagcga tacctgtggc
     3001 ccggaccatc acaaggtggt gaggtccgag ccgattcgca tatctatctt aggcccagag
     3061 ccaatcgatc aaagaagaaa accagccggt cacgctggaa aaccaggatt cctccgcggg
     3121 gggtgctgca gggaccggcc gcggggcagg cggagcagcg gcagcagccg gggcctggct
     3181 gacctttgcc ggtgcattcg gcgtagcggg tgcaacagcc gctggtgcgg ctgaggaagt
     3241 cgccggtgct ggagccgcgg ctgccgctgg agcaggggga agttgggccg ggacggtcgc
     3301 cgggatcggc ggcagtgagg atgcgtcagc ctgcgagggc tgcggtgtga tcaccgcgac
     3361 catgtgctgc tccggtgaac tgatatcgac cggcgttgcc tgtgcttccg gcccggattg
     3421 ctgcgtgccc atcgtccgat cgcgcaacgt ggtcaggcct tccagccgtt tctcaatccg
     3481 cttggtatcg ccgatctcct tcagcatggc ctgatgcttg gcacgtaagg cggcaatatt
     3541 gtgctcaagc agtgccagtt tggcttgatt ggccttgtga agttgatcgt aggaagcttg
     3601 aatggttttc agctcgctct tcaggttggc aagcgttcgc tcatcgcgct gattagcgag
     3661 gtgtgctgcc tctcgttcct gttccaggct gtgaatatcg gcctgagtct gcgccagctc
     3721 gcccgcccgc gtttttactt catgcctggc agtgtcgtag gtctgctgcg agacgcagcc
     3781 tcccagcgtc aatgccgcgc ctccgaccat ccagcagagc gtgaagacag atctgagccg
     3841 cgggtgtggg gtgattgatt gcatgggacg atcctcccgg atacgaacgg tggcgatagg
     3901 tgcaaaaggt ggtcccctca gcggagccac ggtgcctgag gttaattttt cagaaaagtg
     3961 aaaaaacggc aaaatatttc gggaaacctg caggcagcgg tagggagagt ctgagcgacg
     4021 gcgaattgag cggccggtta ttgaatagtg agacagtggg tgggaacggc catctgcatg
     4081 ttgagtcccg cctcctgcca ggggagaagg cgggggccct ggtagcgata cccgccgatg
     4141 acgggatcgg tcgaaagcag gagcggtgtg tcgagatcca gcacgtcgaa atcgcccagc
     4201 cccaacacca ggctgaacga acagcccatc gcgatgcgcg tttcgagcat gccgcccacc
     4261 atgagtcgaa ggccggagga gcgggtgaag tctgcgatgc gccgtgcttc gattaccccc
     4321 gttttcatga tcttgatatt gatatagtcg gcggcctgca tcctgaccac gcggcgcgca
     4381 tcgtccagtg atcggacgga ttcgtcagct gcgacgggaa tgcccgtgag atgccgaatg
     4441 gcgtgaagtc cttcgaggtc gtcacgaacc accggttgtt ccagaaggat caggcgccct
     4501 ccgaactgtt tcactcggcc ggcgaaatgg atgcagtcct cgcgggaaaa gccctgattg
     4561 ccatcaccga taaagctgat tcccggaagc gcctcatgca cagcctgtag gcggcgtatg
     4621 tcttcctcga cgtcggttcc gaccttcatc ttgaacaggc ggaagccttg cgcataccag
     4681 ccgcgcgaga gggccagcgt tttgtcgagg tcgcagatcg gaatggtgat gtcggtttca
     4741 cgctcccgga cgtcggcttt cccccacagt tgccacagcg ggaggcgctg agaccggcaa
     4801 taggcgtcga gaagggccgt ttccaggccg catcgagcgg cgggaaagag cggagcctgt
     4861 tcagtcaggt ggtctgcaag ggcttcgtag tctccggcag agtgtccgat cagtccagcg
     4921 gctaatttct gggcggcagc aaggcaggag gctcgatcct cgcctcccac ttcaggaaac
     4981 ggcgcggcct ctccgacgcc gtgagtcccg tccttcaagg tcacgcgcat gaagaggttt
     5041 tgcgccgtca cacgcgcgcc tgtggcgacg acaaagggat cggtgatcgg aatatcgacc
     5101 ggccagatct cgatgcgctg tatgatgtcg gaattcacca ggggcgtcgt ggctgcaggt
     5161 ggaggctcat ccgtagcgat cgttttgcca gggaagggcg gtattggagt agccgcgcac
     5221 ttcccagaaa cccttctcgt cgtgctgcga gaaggtaatt tccttgatcc atttggcgcc
     5281 tttccaggcg tagcgcttcg ggataatcat gcgcaccgga ccaccgtggt ccttcgtgag
     5341 cggccgaccg ttccatttat aggtgagcag cacgtcatcg tccagacagg cgctcagcgg
     5401 taaattggtc gtgtagtcgt cataggactt gaacagcacg aagcgggcgg agggatgcgg
     5461 ctggaccacg gcggccacat gcttgaagct caccccttcc cattcattgt cataccggct
     5521 ccaggaggtc acgcaatgaa agtccgagat atctttgaac tgcggttgcg ccagaaagtc
     5581 tgtccaggtc caggtcatcg gggccgcgac tgcgcctccg atggtgagcg tccattcggt
     5641 aagcggaata tcgggcttct ggccaaggtc gagcaccggc catgtctcaa cgaggtgctg
     5701 gcctggcggg agccggtcgt cgccttcata aaacacctca cgctcttctc cccctcgccg
     5761 ggctttggcc cagttctcct tggttttgat caatcgatca ttctgatcca ttccggcctc
     5821 cctgttcaca gagtaggaca agatgccctg ttcttacaag ggttgaagcg agcaatgaca
     5881 aagggcgagg acacatgcgg atggcatgaa agggcccatg attctgcgcc aatgtgcggt
     5941 ttagaaggat tctcaatgct ggagcaggag atacattgcg cacagagagg gaaggccgca
     6001 gggggcgtcg acgtcaggca gcctcaaacg ggggccgact gggaacctta gacgtgcagt
     6061 ctggtctcgc gttcacacca gcgttgcggg cgcatcaacg tgcccagtgc cgcaatggcg
     6121 caaatcgtgg ccagtaacac aaagctggcg atgaggaaaa atccaccctt catatcgtgc
     6181 accgagagcg gtcccatgac gtcaccccct tcatatgccc taattgtacc acttcactcc
     6241 gtgcgccagc cgcagccaca acgccatgat tcttcaggtg aattttttct gagacggcaa
     6301 tggcaatggg gacaggggcg catccacacg tgtaaagcgg tttcgtaagc ggggtgcgag
     6361 gtacgggtct gctgtggaac cgaatgtgtt gtcggcatgg cagcgtccag gacatcaatg
     6421 atcgcgtaca cggacgacat tacctccact cgcctcccgg cttcaagagt tctttcggag
     6481 gttgccgccc tgcacttgag ggtaccgatg aacgctggga gcaaaaaaat gcagaagcga
     6541 ggaaaaagag gccgcagcat ggacgacgag gacgtgatct gattgacaca ggagcaggta
     6601 gacacgatga taccgccggg agtaccgaac acgatgacga tttcagccga ttcttctctt
     6661 cccaaggcgc gcgccggtag cggcaaactt gtgttggcgt tactcgtggg ctgtgccgtg
     6721 gcgggatttc tttatttcga tctggggcgc tacctttccc tggatgcgtt gaaggccaat
     6781 cgcgatcagc tgcttgcatt cacggaagcc aactattcga cggccgttgc ggtgtatgta
     6841 ttggcctatt gcgcggtggt cgggctgtca ttgccgggtg gcgcgattat gaccctcgcc
     6901 ggaggatttc tcttcgggag cgtgctggga acgctgtacg tgaatgtcgg cgccacggtc
     6961 ggcgccaccc tggcatttct ggttgcgcgg tatttgctgc gagactgggt ggagcggcaa
     7021 ttcggtagcc gactcggagc tatccaggag gggttctctc ggaatgcgtt cagctacctg
     7081 ctgactctgc gattgatccc gctctttccg ttttttttag tcaacatggt gtcgggattg
     7141 acccgggtga acgtcggcac ctatgtggcg gcgacatccc tcggtattat tccgggaagt
     7201 tttgtgtttg cctatgcggg gcgccaactg ggcaccatca attcgctcaa ggaaatcgtg
     7261 tcccccaatg tattgatcgc gtttacgctg ttaggattac tcgcgctggt ccccatcctc
     7321 tacaagcggt ttgccggtca ctcgagctga acagagagag acgcctctgg cgagggcctt
     7381 gcgtagagaa aggtcgtgta gatgtctgta aggactgccg atagtcagca cctcgttctg
     7441 ccggatgacg agcacaaccg caaactggtg ggcaatgtgc atccatccaa ttgggtgaat
     7501 cctgaatcgg acggtcgata taacatcgtc gtcgttgggg cgggaacggc aggattaatt
     7561 acggcagtga ttgccgcgag cgtcggcgcg aaggtggcgc ttatcgagcg gcacttgatg
     7621 ggtggcgatt gtctcaatgt cggctgcgtg ccctccaagg gattgattcg cgccgcaaac
     7681 gcctgggcac aggtgcgcga tgcgccggta ttcggcgccc gcattccgga tggggcgagc
     7741 ttcgatttcg gcgcggcaat ggccagaatg aggcagctgc gagctagaat cagccatgtg
     7801 gattctgcac accggtataa atcgctgggc gtggatgtct atatcggcca ggcccggttt
     7861 gtcggcccag atacggtgag cgtggaaggc gcggcaggca accggacttt agccttcgtc
     7921 aaggcggctg tgtgtacagg ggcaagggcc gcagctcctc ccatccccgg cctggacgag
     7981 gcgggctatc tcaccaatga aacgattttt tcgctcacgg cgctccccgc gcgcgtcggc
     8041 gtcatcgggg ccggcccgat cgggtgcgaa ttggcgcagg ctttggcacg attcggcagc
     8101 cgagtatcgc tgattgaggc gatgcacggc attctcccga atgaggatcg agacgcggcg
     8161 gaatgcgtcc aacagtcgat gatccgtgac ggtgtggccc tgctctgttg cgggaaggat
     8221 ctccgggtgg agaaggtctc ggacggcaag cggcttatcg tcgattctca tggacgacac
     8281 catgacctga cggtcgatga aatcctggta ggggtaggcc gtgcgcccaa cgtacaaggc
     8341 ttgggattag aggccgtcgg cgttgaattc gataagaccg gcgtcacagt gaacgatcgc
     8401 ctgcagacga cgaacccgcg tatctacgct gccggggatg tctgctcgcg ctataagttc
     8461 acccatgccg ccgatgcgat ggcgcagatc ctcattcaaa acgcgctctt tccccatccc
     8521 ttcgggttgg gatatgcgag catggcgtcg ctcaacatgc cctggtgcac cttcacctct
     8581 ccggaaatcg cccatgtcgg tttgtacgaa gcggaggcag tgaaacaggg actgcaggtc
     8641 gaaacctaca cctataagtt tgatgaggtc gatcgagcca ttctggatgg tgatgaggag
     8701 ggttttgccc gtcttcatat caaagcgggt accgatacga ttctcggggc cacaatcgtc
     8761 gggtcgcacg caggggacgt gatcagtgaa gtctctgtgg cgatgaaagc cggcgtcggc
     8821 gccaagacga ttgccgcaac catccatccc tatccgacac gtgcggaagt catcaagaaa
     8881 acggtcaatc tttggcgcaa ggcgcatttc accccgcgca ccaagtcact gctgaccaag
     8941 ttatttgcct ggctgaggcg atgaatacct atgcggccca tcggcccaat cctctgtctc
     9001 gcattattcg gcgcaacggt gatgggggag gcgcagcagc cggccctgtt gcccgtggga
     9061 acgttttccg ccgcaacaga gggatcagca ttgccggatg gctggcacat gctgactttc
     9121 aagaaaatcg agcggcatac gcaatatgac gtcatcaaag accaggccat atctgttgtc
     9181 agagcggtga gcgaggctgg cgcttccgga ctgaccaaag ccgtgacgat cgacccgcgt
     9241 gaatatccga ttgtccgctg gcgttggaag atcgagaatg tgttgaacaa gagcgacgtg
     9301 agccggaaag aaggcgacga ctatccggcg cggttgtaca ttaccttcgc gtatgagccg
     9361 gatagggtga gtttcggaaa aaaactcaaa tacaaggccg gccaggcgct attcggcgac
     9421 attcccatcg ccgcgctcaa ctacatctgg gacagcaaga gcccggtggg aaccgtggtg
     9481 gacaatgcgt tcacgagttt tgccaagatg attgtcgtgg agagtggggc tcgacggatc
     9541 ggttcctgga tcgaagagga gcggaacgtc tatcaggatt atctctcggc gttcggggag
     9601 gaaccgcccg cgatcaacgg cattgcgatc atgacggata cggataatac gaaagaacgc
     9661 gccgtggcct tttacggtga tatcgagttt gttcgcgctc cgaaatagct gacgtagcaa
     9721 cggatgtgag ggatgaagga gaggccgacc tgtgcagggt cggcctcttc ggacaccggc
     9781 gagctgaggc gggttcgcaa tgtcagcggg ttactgaatg gaattggcga agccgccgtg
     9841 agtaatctca gcccgaatgg tgtcgcccac ctttttgtga cctcgaagtt gtttggtgcc
     9901 ttgccccaca cggaccttca tttgactgcc gtcgtagtcc tcgaccgtat aggtttctcc
     9961 ctgaatatct ttgacggtac cgcccacggt tttccaggcc acgcccggtt tcgagtcgta
    10021 ttggccaggc ttgacggcag ccgattgctc aggcacggat cctaaaagag acgccgcggc
    10081 agctgcggat gtggtcgcgg ccggcgggtg atgtttgccc gacttgtctt tttcttttgc
    10141 tgatgccggt gcaaccgcga agctgatggt ggcgagggtc gccacggcga tgcccagcca
    10201 tgaagtttca acgttaatct tcataagaac ctccttcagt gatgaggact gcgggtcggc
    10261 gattgactga gcaagcccca tgcctccgag atccgggggt gattcgctcg gatttgtgcc
    10321 ggttgtgtcc ggttggcgtg ataagacagg accggcagga gaggaaaacg ccaacatctg
    10381 ttcaattttg cccagccatt ctccggatcc ttcctgactt ctgctgtttc gctgggacac
    10441 gcagttctcc gtatagcgtt ctcggaaatc aaaaactcgt tgtcaacgaa ccagccgcct
    10501 tgtacgttga aatgaacgac agggctttcg cgataaccaa gggaggatgt atgaagcagg
    10561 tgatttggag tgtggctata ctgtcgatgt gtgtcccgtc attggtcttc gcgcaggcgg
    10621 agaccccaag aatcgatcag cgacaggcga atcaggagcg acggattgat caaggcattg
    10681 ccagcggtca actcaatgaa cgtgaggcca ctcgcttgaa caatcagcag gaacacatta
    10741 acaacatcga ggacaaggcc aagtccgacg gggtggtgac gaagaaagaa cgcgccagga
    10801 tcaagcatgc ccaggatcgt acgtcgcgcc acatcgctcg ccagaagcac gaccgccagc
    10861 agcgttaatg tttccatccg gaccgacttc gtcagaaact cagcatgtcg gtccggggca
    10921 cttggtcggt ctctgcgctc gtgcttgttg tcgggtgcct tccatgccgt ccacaggtca
    10981 tactgtgggc ggcatggttg tatctgacct caattgtcat agccgttcca gtcggcaccc
    11041 ggtccctgga tttcacacat cgcgcctgaa tcgattcact tgatcctgct agaatgccgg
    11101 catggatctc atcaccactc acctgaatgc agactttgac ggattggcct ccatggtggc
    11161 ggccaggaaa ttgtatcccg gtgctcttct ggtctttcct gggggcactc aggaatccgt
    11221 ccgaaagttt ctagccgatc acgacctggg catctgccgc ctcaaggatg tggcattgga
    11281 gcatgtgcat cgattgatcc tggtcgatgt tcaagagccg gagcgcatcg gtcccttgaa
    11341 ggtgctgagt tcgcgcaagg acctggacgt ccatatattt gaccatcatg gaaacggcga
    11401 aggggtagag acgtcggcct gggcgtcaaa gacacagcgc catatcgagc cggtgggagc
    11461 cactgcaacg ctgctgatcg agcgcctgca atcgcagcag gtcgtcctca ctgctgctga
    11521 agccaccgtg ctggccatgg gcctgtatga ggaaacaggc tcgctggcct atcccacgac
    11581 gactccgcgc gatctggaag ccgcggcgtt tgtcctccgt gccggcgccg atttgaaccg
    11641 ggtcgcagag acgctgcagc atccgcttga tccggatctc attgccctgc tgaacgatct
    11701 gcttcaatca ggggagatct actacttaga aggccgaaaa atcctcgtcg cttcgagtgc
    11761 atacgatcga tatacgggag accttgccga ggcggttcag cggctcgcgg aactgcaagg
    11821 atttgatgcg gtcatcgtgg ccatcgcgat ggacgagaag gttcagatta tcggacggag
    11881 ccgcaggccg gagatcgatg tggcgtggat tgcgcgcgag tttggcggcg gcggacatgc
    11941 cgtggcggcc gctgccagtg ttaaaggccg tacgctcgtg gaagtgcagg aacaactgac
    12001 tcgtctgctg accgaacggt accgcccgac gttgttagcc cgggatgtga tgaccacgcc
    12061 cgtcaagtcg attgtcgcgg atgccaccgt gacggaggcg gaacggtcca tgaccaccta
    12121 cggtgtcaac gtgctgccgg tggttgatac gaaagatcga tacatcggca tgatttcacg
    12181 ggaaaccgtt cagaaggccc tgtttcatca actcggagat cagccggtag gagatctggc
    12241 cggcagcgga cactatagcg catcgcccga cacgccgttc catgacatcg agacacggat
    12301 gatcgaattg aatcagcgtt tcgtaccggt gttgtccgac ggcaagatag tgggtgtcat
    12361 cacgagaacc gacctgctcc gtagcttgca tgacgatgtg ctggcatctg cgcgcagcaa
    12421 accgaagtca ttcataggac tggagtcacc cggaggagtg cggaagcggg atctgaaagg
    12481 actgctgcgg gatcggttgc ctcctcgcgt ccatgacttg ctgcacgcat caggtgtatt
    12541 ggccgaacga ctgggcttgt cactctacgt ggtcggagga ttcgtccgcg atctgttgct
    12601 cggtctcgag aatctcgatg tggacctggt cgtcgagggg gatggcatcg cgtttgcgcg
    12661 cgccctcgcg aaggagcgtg ccggtcgcgt caaggtgcat gaacggtttg gcacggccgt
    12721 ggtactgctg ccggacgggt ttaaaatcga tgtcgcaaca gcccgtaccg agtactacga
    12781 gtatccgacg gccttgccga ctgtggagca aagttccatc aagaaggatc tttaccggcg
    12841 ggacttcacc atcaatacgt tggcggtggc gctgaggcct cgaaatttcg gtcagctcat
    12901 cgatttttac ggcgggcaac gcgatctgaa agagcggctg attcgtgtgc ttcatagttt
    12961 gagttttgtt gaagatccga cgcgggtgtt tcgggcgatc cggttcgaac tgcgcttcga
    13021 ctttcatttg agtaaagaca cgttggcctt gattaagggc gcggtgaaga tggaactgtt
    13081 ccatcgactg tccggccagc gcctcttgga tgaactgcgg ttgttgtttt ctgaacgcac
    13141 cccgaggcag gcggtgcgcc ggctagccga ccttgatctg ttgcggttta ttcacccaac
    13201 gttgacctgg tctgccaggc tggatcgacg gctcagcgag ctggaagcgg cgttggattg
    13261 gtatcggctg tcgtgtctcg accggaccat cgatggatgg gtggtctacg ccatggcgct
    13321 cgcggagacc atgccggatg aagccgtccg cgacatgctc gaacgttttc cctttaccga
    13381 agcggaacgg accgccataa accaggctcg gttcctgacg cagccggtat gccggacgtt
    13441 agccaggcgt gcacctctcc ggccatcgga aacggtcgcc gccttagccg gcttctcaga
    13501 agagtgcctg gtgttccttc tggcgaagaa tggctcggac accgctaaac ggtctctgtc
    13561 ccagtatctc actacgtatc gtgacataaa accggctctc accggaaagg cgctccaggc
    13621 ccttggtctg aagccaggcc ctgtctaccg gaccatattg gagcggttga ccgaggcgcg
    13681 tttaaatgga gaggtacaca ctgaagagga ggaacgggca ctggtcaagg atcttatcgc
    13741 gcgacggcgt tcagcctcct aggctgcagc gcgaggtggc gatgccacgc atcggcgatg
    13801 gccacaaggt gagagagggg aggcctatgc gcacccctag gcgaccgaac tgcagcgagg
    13861 ggattaagcc agcggctcaa ccggctcgag ttcgtcgtgt gtatcgacgg cacgagcctc
    13921 tttccccatc gcggcgagaa ggccgtcgta gacgatgcga gccgcgtcag accatttggg
    13981 attgaatggg cgaccagcga aagcggcctc agccgctttt ttctcatcgt gggtaatttg
    14041 tcgaggagtc agtgtggtgt ccatacgaat aataatagat cgcttcaggg caatgtcaag
    14101 gactctgcgc ctcgaagaac ccctctcgtt cgttgggggc tgtgcagaaa tctccggcag
    14161 tgatcaacgc agagacttca ctattcacgg ttttgcccca agcacggcag ggggaaggat
    14221 tcgatcaagt tccgcatacg ttgaccgaaa cagttcagat gccttctctg cgctgatcat
    14281 cctaaaggac agggtgtcgc ccggtgccag ttgcgcagca agcgaccgat cggcaccgat
    14341 catcgtggcg agcttggcat acccgcccgt cggctgacaa tctgccatca ggagaatcgg
    14401 ttgtcgattg gacggaacct gaagactgcc gacgcatacc gcttcggaga caatctccgc
    14461 tgaagcacga tgcgggagct ccgcgccctc caagcgatag cccatccggt cggattccgt
    14521 cgtcacccgg tatggactgc tggttaacag tcgaatggcg tcgtcggtaa aataatctga
    14581 ttgcgggccc ggcatgactc gcacggcggg agagcccgtg taccgcggtc gatatcgttc
    14641 cggcagcgaa cgacctatgg gctgtgctgc agctcgtgaa gcagttccca cgaagagttg
    14701 atcccatttc ttcaccgctc ggcctgccag cccgcccaat ccactccgca catgggttga
    14761 aagacttccc agtatcattg ggccggtgat gccgccagcc actgtgagat aggcgcgggc
    14821 accctgtcgt cgcatcccga actgtaaccg gcttccagcc ggcatggcga ccacggtcca
    14881 catgggaagc gcgagaccgt tgctggtggg tgaaagatcg gcaccggtga tggcgatcct
    14941 gaccgcttgc tcaaacagca gttgaggccc ctggagtgtg atctccaaac cggcggcctg
    15001 gtcaggatta ccgagcaggc gattgccgac catgagcgcc cacgggtcca tcgctccact
    15061 caccgacacg ccgaatcgtt gatatccgga acgaccgaga tcctgcacgg tggtgaagag
    15121 gccgggatgc agcacatgaa tgagcggctg tttagtcggc atgatcgagt cgtctgacgg
    15181 aaattccgct ctccgcgaac attgttcgca gcgcatgggc cagccgaaga gcatccgggg
    15241 tatcgccgtg gaggcagagg gtatcgatgt ggaggtggag catggtccca ttggctgcaa
    15301 caacagtccc atcgtgtacc agtgcgtgcg cccgcgcgag cacagtcgat tcatcatgga
    15361 gcaccgcatg cgcctccgtc ctgggtacta aacgaccatc ggcttggtag gctcgatcga
    15421 caaatccttc cgcggcgact gctagcccat gcgcccttcc agaggtgagg agttcggaac
    15481 cggccgatcc gatcagaatc aaccggcgat tgagttggac gattgcggct gcgatcgcat
    15541 ccgcaagttc cggatcacgt gccgccatgt tgtagagggc tccgtgcggt ttcacgtgag
    15601 aaagccggat gccttccgcc tgaccgatcg tcatcaaatc actcacctgc gagagaatga
    15661 ggtcgagcac gaacccttgg gagagcggca gctcccggcg tccgcgtgat tcccgatcag
    15721 gtaacccggg atgcgcaccg atcgccaggt cgtactgtct cgccagttga atggtactgc
    15781 gcatcagtgc cgcatcgcct gcatgcacgc cgcacgcgat gttcaccgag gtcacgtacg
    15841 gcatgagacg agcctccaca tcccgttgct caggcgttgc cgcttcgccg acgtcacagt
    15901 tcagatcgat gtggcgcaac cgggtcatgc ctggtctcct gccagttgcg tgaattcttc
    15961 ctcctcgatc gccacgaatc gcacctggtc gcccggagcg agcagaaacg gcttgggcct
    16021 gtggagatcg aatagcacga ccggcgtgcg cccgatgatg cgccacccac cgggactggc
    16081 ttggggatac acgccggtct gtgtgcccgc gatgcccact gagcctgcgg ccacatattt
    16141 gcgcggcgtc ggaaggcgcg gcgcggcaag cggcgcgggc acagtgctca ggtagggaaa
    16201 gccgggactg aatcccagca tacacacacg gtacgccacg gacgcatgga gctcgccggc
    16261 ttcttctgga gtgagaccgg cttgccgcgc tacatcgggc agatccggtc cggctgcgcc
    16321 tccataccaa acaggaatgg tgtgagtaat ggacgcgcgc gaaggcgcga ctactgtgtc
    16381 caccgtcaat gcacgcacct ttttcataag tgtgtcggca tcagtgagta gcggatcgaa
    16441 atagactgtg gctgaccggt aggtgggaac cacttctctg aagcccggaa ttttcgactg
    16501 gtccaccgca gcggtaaagg ccaacaccag ttcattcgta tggaggtcaa tcccgtctcc
    16561 gaactcaacc gtaaccgcgg actcgctgag ctggatcatt cgaggaatca tagtcaccgc
    16621 ctgccgcgcg agatgctcac acactcacga ggggagttca ttccggtaac ggtctcccct
    16681 tggtttcggt cgcgaatgga agtatggcca agccgagcag gtagatcaac gcgatggtac
    16741 ttgcggcatt gttgaacgat cccagcatgg tgacgagcca gcccgtgacg aagggggccg
    16801 cggaggcgag aatgcgtccg gcattgaagc aaaagccgga gccggtggca cggagccgcg
    16861 tcggatacag ctcgggcaga taaatcggaa agccgctaaa gatgccgtta ttgaaaaatc
    16921 ccagtaccgg caacaggagc agcacttctg cgtagctgtg cggcacgaaa taggtcgccg
    16981 gcagcaggat cagactgcca aggcacatca atccgaacac ggggcgacgt ccgaaccgtt
    17041 ccgcgagcgg gccgaatccc agatagccga aaagcgcgcc tgcgttcagg gccatgatcg
    17101 cgtaactcac tttctcggcg agcgcggcgg agtcctggcc ctggagatcg ggcatcccac
    17161 ggatgagggt cggcgcccag ttggtggcgc cccagactcc gaagaccgcg acgaaggcta
    17221 atgtagaccc gatcagcgta tcgcgacgta aagaggggcg gaacaattcg acgagatgga
    17281 gccagctcgt gtgggctgat cgcggttctc gctcatgggc ctgcacccag cgctcgggtt
    17341 ctttcaccca tcgtcggacg aggagggcca caaaggccgg aaggattccg atgagaaaga
    17401 gcatccgcca gccggaatct ttcaacagca ggttgcagcc ggcggcgata aaaaagccga
    17461 aggcccaggc tgactgtaag atgcccgccg ccctggatcg cttctcttca ggccaggtct
    17521 cggccacgat ggcggctccc gccgcccatt ctccgccgac gccaagcgcc gtcagaaacc
    17581 gatagatcgc gagatgccac cattcctgcg cgagtgcggc caagcccgta aacacggcat
    17641 agatcagaat tgtcgcgatc agcgttttgg tgcggccgaa atagtcggcg gccataccga
    17701 agccgatacc tccgagggcc cacccgatga ggaacacgga aaagacgatg ccgccgtacc
    17761 atccgatttg ttcggacgtg acctcgccgc cggtggcgcc ggcttgcaag agttcatgca
    17821 gcgcgggatg gagcacgatt gcatagatcg tggcatccat ggcatcgaat acccagccga
    17881 gccaggcgac gaacaacacc agccattgat atgtcgtgac gccatgcatc caagccacgc
    17941 tgcggttctc ctctgtgcgg gtcgtgcgcg ccacgctacg gggagaacgc ggcgctgtca
    18001 aggtgaagcg cgcaaagcgg acatggtata gtccctcgca ctatgccgcg tatcgattat
    18061 taccgcgtcc tcggggtgtc acgagacatt tctgatgacg agatcaagaa ggcctaccgg
    18121 aagctcgtct tcgagcatca tcccgatcgc aatcccaaca acagcaaggc tgaggagaag
    18181 atccgtgaga tcaactccgc ctatgaagtt ctcggggatc ccgagagccg gcgcacgtac
    18241 gatcgcctgc attggggcga ggagatgcgg ccggagaccg tcgatcccgc gctgattctc
    18301 gaggagatgg agaagaagct cttcgacgag ggccgcaagg aagtgttcgc cgtcctgatg
    18361 aaaatggtgc cgcggatcaa atccgaattg gccatcattc gggaacgcac ggtggcgcac
    18421 caggggtatg atacgttcaa ggaaccgatc gtcgaggcgc ggggggctga ggtgctggat
    18481 gaattcgtga cgccggagat ggagcaacgc aagcatcgcc tgctcgaagt ggccgtacag
    18541 atgatggtgt cgcagtccgt ggttgccagg ggcgacgaag gcgggattcg cgcgctacga
    18601 ggccgtctgg aggagatgtt ccggaaggga cgaatcaatg ggttcgccac ggcgctggag
    18661 ctgctgtatc aacgcagatg aataagaagg taacgctcac gcgtgaagag tacgccacac
    18721 gcgtacgatg aaacggttcc ggagcgttgc ttcctcggac gcggtttccc tttacgtctc
    18781 cgaaagcggt cctgatacaa atcgcccgcc ttgcatcact cctgcgatcc gttcccgttt
    18841 caggagcagt ccgatatttc ttaacggatt gccttccacc accaagagat ctgcctgctt
    18901 gccggcttca atggtgccga tttctgccga aagtcgcagc aatcgcgcgg cggcggacgt
    18961 gctcgtcatg atggcatcca tcggtgtcat gcccagggtg accatgcgtt ccaattcctg
    19021 cgcattgtcg ccgtggtaat taaaaggtgt gccggcatcg gttcctagag caatggggac
    19081 gccacgccgg acggcggcgc ggaaactctt ctcgtgttgc cggaccatgt ttttggcctt
    19141 tgagcgggcg ctgtcgggga tgccgcagcc ggtcggacag gcagccgtgg tggccagagc
    19201 ggatagtgtg ggcaccatat acaccccgcg ctgagtcatc aggccggcgg cctcctcgtc
    19261 catgagcgtg gcatgttcga tcgaatggac cccggcgcgc agggcgttct tcatccccga
    19321 ggcaccatgg gcatgagccg ccacgtgccg gccatgggcg gcggcgactt caacggcggc
    19381 tctcagttct tccacagtca tctgggcctc gtccggggag gtccctggag ttaggacccc
    19441 gcctgaggcg attaccttga tcacttccgc gccggccgta agctgatcct gcacggcggc
    19501 ccgcacggcc tcgatcccct gtgcttcacg gccaatgaag cgggcatgtc cgccgggcat
    19561 acagatcgca agtccggcgg cgaggatgcg tggccccggc gtgagtcccg aggcgatggc
    19621 cttctttaag gcaaacacgg catggtcgcg gaagccgaca tccctcacgg tggtgaagcc
    19681 ggcctgcacg gtgcgccgcg ccagttccgc ggccttcagc aacgtcaccg ccgaggattc
    19741 ctgctcgacg gccgcaacga catcggcttc tgcacccagg caaaagtgga catggcaatc
    19801 gatgagaccc ggaagaatcg tcaggccacg gccgtcgatg cgttgtgccc ctcgaggcag
    19861 acgtacggtc tgatccggtc cggcagccac aatgcgatcg ccttcaatca cgaccgtgcc
    19921 gcgctcaatc ttgcggcctt ggccgtcgag gatacgaatc tgtcggatgg cgatggtcat
    19981 ggggcctcgc tgatgggaat ggtgacgatg acaccgccca tgatgtcgtt gagtttatag
    20041 tcgcgcctgg ggctgttcgc atgcccgttg tgacaggata cgcagctctc ggagaccgcc
    20101 cggtcggcgt agatgccttg gaagtaccgc accccgccct gctgataaaa gcccgtgaac
    20161 ggtttctccg gcgccttcat gacgacttcc aggccgcgtc gttcgaactc actgttcggg
    20221 ccgttccaca cgtaaatcgg ggtgaggctg gcgagccgga aactcagttt catgtctttc
    20281 tgggcaacca gccggcctga ttcgagaagg aattgggcgg gcaggggaag tcctttttct
    20341 tctttccaat gttcgagggc ttcgaccacg ccttgggtgt gcaacttgtc gacgacgttc
    20401 tgcgtgtagt tggcgcgatt ggcatcgatc accgcatgaa tgaaactggt cacccgttcg
    20461 ggcgcgacca tgtcggcttt gcgtgactct gccacggcga gggcgatgac ccagtaggtg
    20521 atcgccgcca cgaagccggc tacccccgcc atgacgatcc agaacccgtt tcgactcatg
    20581 cacccctcct cgccgacaac tgtgattggg tataggtttc gaccgccgcc tgcaccgcgc
    20641 gacctggctg atccagccag ccgtgttgcg cgaaaatgtc ttccaaggcg ttgagcagcg
    20701 tcagcacgtg cgcctgctga caggactcgc ccatcagccc gattcgccag acccgcccgc
    20761 gcagcggccc caggccaccc ccgatttcaa tcccgtggtc ctgcaacagc tgcgttcgca
    20821 ccagcgtatc gtcgatgccc tcgggcaggg tgacacagct gagcatgggg agtcgatgcg
    20881 ccgccggagg gagcggccgt aggcccagag gctcaaggcc ggcgagtaag gcgtcgctgt
    20941 tgagttgatg gcggatgaac cgcggtgaca gtccttcctc atggatcagc cgcagggctt
    21001 cgtgcaatcc atacagcata gagatgggcg ccgtgtggtg ataggcgcgg ctgcggtcat
    21061 tccaatattc ggcaatcaat gagaggtcaa ggtaccaact gtgacagggt gtccgtcgct
    21121 gtcgaacggc ctccatggct cgggggctca ccgtcaacgg ggccaggcca ggcggacagc
    21181 tcacgcattt ttgcgtgccg ctgtagcagg catcaatgcc ccatgcgtca acctcgacgg
    21241 ggaggcctcc gagggatgtg acggcatcga tgatcaataa ggcgccgtgc gcccgacaaa
    21301 gggcgccgac gtcttcgagc ggttgccagg cgccggttga ggtttccgca tgcaccagta
    21361 ccaccgcctt gaccgggccg cctcgagaca aggcatcgtg cacggcatcc aacgaaatga
    21421 tctgtcccca gggcgcctcg atacgtagcg ggataccgcc gctccgttca atcatggtgg
    21481 ccagtcgtga accgaacacg ccgttgaccc ctacgatggc gcggtcgccc ggctcgatga
    21541 gattggcgat cacggcctcc atgcctgccg atcccgtgcc cgggagcgcg atggtgaact
    21601 cgttctccgt ccggaacagg gtgcggagcg aggcttgaat ggtattcatc agattcagga
    21661 agatcggatc cagatggccg accagtggct gcgacagggc atgaagcacg cgcgcatgca
    21721 ccatgctcgg gccggggccc atcagtaatc gatgcggggg gacgaatgcg tgatcgtgcg
    21781 aggaaaggct catggttgac gctgatcgtg tccgctcgcc acggaaggtc gcaccgtctc
    21841 gggagcaacg cctggcgcag cgagtggcgt agtatagcga atccagaggg ggttcagcca
    21901 tgagattgtg gcgagatccc ggcaccctct gttgcgggat gctctgcagt ttcaccgcca
    21961 taaggccggt ggtatactcc ggcgcgcctt acccttggag gtctcgtgga cgctgacgaa
    22021 tcgactggtc cggtctcgca atcatctcgc cctccagcgc cctgtgtcgg ggcgcctcct
    22081 ccgccgcatg cgtacaatcc cgggttttcc cgtgcggtca cgttgttatc tgccgtggtg
    22141 ctgtcggctt cgatcgcggt tgtggcctgg ttatcgttcg atatcccgag agtggagcgg
    22201 gtcgcggatc ccggccgggc gctgagtcat atggtcggtc gtctgatgga tcaggcagac
    22261 ggcgtgaaga cgctgccggt gtgggaacag ttcctctatg acctcacgat gggaagcgat
    22321 gcgaacgatc gtgagcaggc catcgagtgg tatcgcgaac tggccgaaga atcgtccgat
    22381 ccgtttgtcg atttgcacct ggccatcctg gagggcgagg cggggcatct tccggaggtt
    22441 cggcaacgta tctcgcgatg gatcaggcag tccgcaccgt atccgttgtt tgcgcgactg
    22501 ttacaggctg gatacgtcga tgcgcatgtg gcgcgcagcg cggggttcga tctgcaagcc
    22561 tctttggcag agcaacccgt ttccggctgg ttctacagcc ggctggcggc tcgtattgcc
    22621 gaacgcgcag gggatcgtcc gctgctcgtc acgattgaga cagccgacca gcaacgcatc
    22681 gaaacattgg tctggcgctc acgggcgttc gccctgctcg agttgggcct catggtcgtc
    22741 gggggaatgg tcctgatggt atgggtgcgg cgaggtacag gcgcgaacat gtttcgggtc
    22801 ggatccgccg agttgccgcc cctgtgggca ggccgtctgg gggccggtgt gttgctgcgc
    22861 gggggtgccg ttggtgcgtt gttgacggtg gcgtttctgt ttgccgccgg cgacgtgccc
    22921 tccttgcggg tcgttgcggt gccgctgtcg aacctgccgc tcctggcatt ggcctattat
    22981 cacttgcttc ggccccagcg gcagacattc tggcgaggac tggggttgag tcttgagccg
    23041 cgtcatgtgg gacaactgag tttggccgtc ttggcagtcg tggcagccgg acttgtggga
    23101 gagtgggtgt tgggccgcct tgccgagcca ctgaatttaa ttagtcactg gaccgagtgg
    23161 ttcgatgcgg atctcgtatg gggcacgcct ccgactctga tcgtcagttt gatggaatat
    23221 gtggtctttg cgccggtctt tgaagagttg gccttccgtg gactgttatt cggcgtgttc
    23281 cggcggcggt tccaatgggg cacagcagcc atgctgagcg cggccttgtt tgccattgct
    23341 cacggctatg gattgatcgg attcttgagc gtcttctgga gcggcgtgat ctgggcgtgg
    23401 gcttatgagc gaacggggag tttgtggccg ggcatgatcg gccatgccgt caacaacctc
    23461 ctggtctgcc tcagcgtgat ggcgctgttg cggccctgaa agcggtgttc gagcgagacc
    23521 actgcatggt tattccgatg ggtagatgtg cggactggta cgtggtggaa aggtgataac
    23581 aacggtcaca gccgccggtg agccgtcacg atcagaattt gtgccggccg cttgctgatg
    23641 ttgcgccagc agtgccggtt gcctgccggt atcccggcgg catcgccgcg cttgagctgg
    23701 tggacgtcct cctccagcgt caattcgaga gatcccatca ggacgaccgc gagttgttct
    23761 gcctgccgga cgtagggttt atgaccgctg gctccccccg gctgaatcgt gatcaccata
    23821 ggctcgaact ggctgtcctt gttgaacggg ccgagcgctt cgatttttgc acgagaccac
    23881 tcgctttgga cgaccggccg agaatcggac cggatgatgg ccggaggcgt cgggtcgatg
    23941 gcgcgaaaga actctcccag ggtgacgccc aatgcggagg cgatcttttc ggtggaggca
    24001 atggacggcg aagcctggcg tagttcgacc tgagagatga agctgggaga gaacccgcac
    24061 ttgtcggcga gtgttcgcac tgaaagatga tgagatttgc gaagccgccg gacaatgtcg
    24121 ccgacgtgca cctcggcttt ggtggcagga ggtgaggcgc gtttcagtgg cttcgttttc
    24181 ttggtagccg tcatttgtcc gttaagaaca catacataga gccgagtgcg aaaggccggc
    24241 tttttacctg tgtaacacgt ttttgtgggg agtctcaagg atgagtctct tcccccgtcc
    24301 tctgcgctac tgccgtctgt cgatttctcg acaccgcgtc ctagggactt ccccagcttc
    24361 ccagaccttc gtaatcgggc taaggaagtg tccagtatag ctggacagtc gttcagccat
    24421 tattgtggag tgttcgttgc tcgttcgtca gtcactgatg gcctgatctg aaccaggacc
    24481 agtgacacat ccagatgcga tgtggggagg gagcttgaaa gacaaggcca catggttgac
    24541 gttgacgata tttgtaagtg catgtgccct gttatggctg acaggcgtga ccagcaccaa
    24601 gcatctcgtg gataacctca ttgcgggcta tttgttgtct tggggcttgt atgcttttct
    24661 ctccgatctg ccgcgcaggg agattcaggg acggttcatt ttgatgaccc tctgcgggat
    24721 tgtggtgttg gggacagccg aattgctcgg cgtgacggga ctcgtgaatt accaaatgct
    24781 gtttgggacc caggggcgtg aatggttcga tcgctccgga tatgtccgtg atccggaact
    24841 tggatatcgc cgtcaggcgc attaccagga ggaaggggcg tttgtgcgag gaaatatcgg
    24901 tgaagcgctc tgtcttccgg cgaatgcacc tcaacgattt gatctccggt atgaccatcg
    24961 ggggtttcgc aacgatacgg atctggatcg ggcggaggtg gtggtcattg gtgattccta
    25021 tgtggaatcg cccatgctcc ctggcgacag tcttctgacg acgcaattaa gccatcggct
    25081 gcgcacgtct gtcgcgaatt tagggattag cggatatggg ccggagcagg aactcgtcgt
    25141 gctgaagcgg tatgcgctgg accttcagcc gaagacgatc gtgtgggtat tttttgaggg
    25201 aaacgatctc tatcaattgg atccggaaga gcaaaacctg agcgccgtgc ccgacaccag
    25261 ggccgaacac gacgagtatt ggatgcgctc gttgacgagg aacctgctgc tcctttcacg
    25321 taaagcggtg cagggatgtg tgccccatcc agattacttg cgacttcgcg gaacgtttca
    25381 cgatacagag ggcaatgaaa ccctgttgta tttctgggaa aggctcggcg aattaaaacc
    25441 gacggacaga ctccgcctcg agcggctgcg atcaattttg accgaggcgt atcacgtgag
    25501 tcgtcagcaa ggtattcgcc tcgtggtggc gtttgcgccg gtgaagcatc gggtgcatca
    25561 gggattgaaa aacttcgagc cactcaccgc ggaaatgaga gagtggccgc tcaatgaact
    25621 gcccgatgaa gtggcgtcga tgctgaacac actctccccg gatatcgaat tcatcgattt
    25681 gactccgccg cttcgcgagg ctgctgcaca gggtgtgttg acctatcttc ccgatgacac
    25741 tcattggacg gcggaggggc agcgagtcgc cggtgaagcg atccatcatc tccttgctgg
    25801 cggccagact cgcgtggcta agcagtaagg cgtggctagg ggcagttcct gacgcctgat
    25861 tcctgctgga gggtcgcgag tgtgcgatag agatccggat gccggagggt gtagcgtaag
    25921 ccttcgagcg ctttgcgatt gttaatccgc ttgcccggtt ggctggaggt ggcctcccgc
    25981 gggctcacaa tgccccatct ggtcgacact tctacgcaaa tctcggtcca gcggcgcgga
    26041 agcccgtcgc tgatattgta gatgtctccg gcgcgtccga tttgcagggc cagaaggcag
    26101 agcgcggcaa gatcttcgac atgaatcaag ttcacaaatt tattcgtggg gccgacgcgc
    26161 ccttggcgga tccactccac cggattgcga tgggggccat agattccggc cacgcggaga
    26221 atgatcccac catgcttcgt gcggaggtat tcctcccctt ggacccgtgg aaggtcgaca
    26281 ttgacggggc acgtctcgtc gatccatggg ggcatgtctg tcaaaggctc atctcctcga
    26341 tcgtaggcgg acgtactgcc taacaccacc aagcgtcgcg aatggctgca ggagtgtgtg
    26401 gcgaaggcct tcacctgctc aagaggaact gccggaaacg tccagatcag gtccgcgtcc
    26461 aacggcaacg cagaccatgt ggaaggactc tcgagatcga accggatgcg ggcagtctgg
    26521 gctatgtcgc tgaggtggtg ctccggctgg cggctgctgg ccagaatggg cagcgattgt
    26581 tcgcgggcca gcttctgaat ccatcggccg gtgtagccgg ttccgagaat cactatgggg
    26641 cggagcgagg gcatccgggc atcatacccg aactgccggt tcgtttgctg ctgccggttt
    26701 gagcctattc tggttctagt ctcgggacag agtcgcatgc taaaatccgg ccccgatggc
    26761 gtctttcaac ttacgtcagg acgagacggg tgacatgatc ggccgaccga ccgatgcgca
    26821 ggcgcagcgg cggcagcgga tcctggccgg acttgccggc ctgctggcct gtctcttttt
    26881 tgtgctggat cttcagttgc cgctgggtgt ggccaacgcg gtactctaca gcgcggtcgt
    26941 gctcctgtcg tctgccagtc aatatcgatg gttgccgatt gccactgcca ccgcgtgctc
    27001 attgctcacg atcattgcca ttccgttcag tccgcggatc cccaatcttc ccccctggtt
    27061 tgaatgggtc aatcacctgt ttagtctctt cggcgtctgg gctcctgtgg tgtttgtcta
    27121 tcagcgtcgc cgtacggagc gactgctcga agaaatcaac gagcggctgg aacgaggggt
    27181 agaaacgcgg acggccgatc tggccgccag ccggctggcg ctggagcgga gcgaagaaca
    27241 gttgcatacg ttgaccggcc ggattctcac ggcccaggaa gaagaacgcc ggcggattgc
    27301 ccaggacctg catgatgatg tcaatcagcg gctggcgctc ctcatgttgg agcttcagag
    27361 cgttgaccgg cagattggag tatcacctgt ggcagcccag gacgggatac acaatgtgtt
    27421 gaagggcctc gaggctctgt ccgacgacgt ccgctacatg gcgtatcgct ttcatccatc
    27481 cattcttgat gacctgggtc tgaaggcggc cttacagcgc ctcttggatg atttttcgac
    27541 tcgaacgggc gtcaaagccc tgttcgtcca tcaacctctt gaccaccccc tcgacaaaac
    27601 tgcttcgacg gcgctgtatc gcgtcgttca ggagagcctg tccaatatcg cccgacacgc
    27661 gaaagcgact cgggtggaag tggaggtgac ggtcgaagag gagggggtcg tcgtagtggt
    27721 acgcgatgat gggaagggat ttgatcagct gacggtagaa cgatgtgagg gcgggttggg
    27781 tctgttgaac atgcgcgaac gcctcttgtc tgtacaaggc acgtgcgaag tcgaatccag
    27841 ccccgggaaa ggaacaaccg tatccatgta cgtaccgctt gtacgggtgg caatatgacg
    27901 cttccgcgtg tgttattggc agatgaccat accctcgtcc tcgagggatt tcggcggttg
    27961 ttggatgatc agtgtgaact ggtcggcact gtgggggatg gccggtcgct gctggaggcc
    28021 gtgccgcagt tgaagccgga catcgtcatt ttggacatct cgatgccggt gctgaatggc
    28081 atcgatgccg cccgtgtgat gaaggtcaag tttccacagg tcaaagtggt gtttatcacc
    28141 atgcatgccg atccggccta tgtgcgggca gcgtttgagg ccggcgcctc ggcctacctg
    28201 ctgaagcgct gtgtgggaga ggaattggcc caggcgatcc gggctgtgcg gagcggcaat
    28261 ttctatgtga cgcctctggt cacgaaggaa gttgtcgaaa gcatgctccg cggcgtggac
    28321 ggcggagctc catccggccc tgagctcacc actcgtcaac gcgaagtgtt gcaactcctg
    28381 gccgaaggcc acacggtgaa ggacattgcc ggcacgctca agatttctcc tcgcacggtt
    28441 gagtttcaca aggggcaaat catggaacag ctcaacctgc ataccacagt ggaactcgtg
    28501 aaatacgccc tcgcgcaggg tctcaccagc caaacttgat ctcctgctcg gtttccgccc
    28561 ccgtctttct ctgctaccag tatttaagct agtatatttt tgatgtaaaa cctcgctttg
    28621 ttacgcgtgt ggtttaccct tcacttgcct actatacgta tcccttttct aagcagagac
    28681 tcgtaggatt atgagaaaaa agatttcccg tccccgtgtg ctgttaggtg attcctcacg
    28741 ttccatgttg gcctttctcg agattctcct ggagtctcat ttcgatgtcg tcggctcgga
    28801 aaccgaaggc gacgccttgg tcctgacggc aaaaacactt gcccctgagt tagtcatcct
    28861 ggatttttcc ctctcgttcc tcgatggttt gtcggtcggc cggcagcttc aggaggctgt
    28921 gccggacagc aaggtcgtgt ttttttcgtc tcacgaagat gccgcctatg tgacggccgc
    28981 ctttgaggtc ggcgcgatgg gctatctggt caaacaccgg acggtggacc ccggccatta
    29041 tctgcgccgg gtgctggacg gggagcgggt ctgttgtccc gacgatttac acaagcgggt
    29101 ggggcgcccc aaaaaaaagt agtgccgact ccatgcatgc agtcagcttc gcgcaaaagg
    29161 agaccgacga tggtccgagt cgtaccgatg tgtgagttgt gccgtcgggt tcgtgacgat
    29221 ggattttccg ccaggggaac gaattgttgg gtcgatttcc cgagttacct ggcgcggcat
    29281 gtggtgtcgc cgtcccaggt gcggttttcg agaaattact gcagcgaatg ccgcttgtcg
    29341 tatgagatct taaaatctta tggcgagcag tgagacggcc ggcctgctga tgatccggct
    29401 tagatcgggc cgacgaagcc tcaaggggtg accccggtgc tcccccgcac ggtccccgtt
    29461 tgtaccgtcc cgcccccgtc gtcttccttc cggccatttc aaatctcaac ggtttgaccg
    29521 catgttcagc tcgtgacggt tgtgttacga tcgcccgatg acgccggttc ttccctttca
    29581 tcctatcatc gccgactggt tcacggccaa atttgcggtc gcgactgacg ttcagcagca
    29641 ggcctggccg gagattcagt cgggccgtga tctgctgatt tccgccccca ccggatcggg
    29701 aaagaccctc gcagcatttc tgtcctgtat cgatcggtta tttcagcagg cgctgcgttg
    29761 tgacctgcgg gatgaaacac aaatcctcta cgtctcgccg ctcaaagcgc tcagcaatga
    29821 tgtgcaaaaa aaccttcaac aaccgcttct ggagatcggg caggctgccc tctcggcggg
    29881 actgttgctg ccagacctcc gggtcatcgt acggaccggc gacacaccga tgagcgagcg
    29941 gcagcaaatg ctcaagcgtc ctccgcatat tctgattacc acgcctgaat ccctgtttat
    30001 tttgctgacc gctgaaaaaa gtcgggcgat gttgaagacc gtccgaacgg tcattgtgga
    30061 cgaggttcat gccgtcgccc cgaacaagcg aggggcgcac ctggccctgt cattggagcg
    30121 cgtggcggcg ctggccggtg gtgccgttca acggatcggt ctctccgcca cccaacgtcc
    30181 gattgaacgg atggggcact tcttagtggg gaacaggtcg tcctccccac agacgcagga
    30241 tgagcattcc gcagccgggt gttctggcga cgagatgccg gtggcgaacc atgtggcgat
    30301 catcgatgtc ggccatcgcc gcgacatgga cttggcggtc gaagttccga aggacgaact
    30361 cgggcccgtc gcgaccaatg cgatctggag cgatatctac gatcgggttg ccgcactggt
    30421 ggaagcgcat cgttccacac tggtcttcgt gaatacgcgg cgcttggccg agcgggtctc
    30481 gcactacttg gaagatcggt tgcgtcacct gggcgaaggt gtggtggcag cccatcacgg
    30541 aagcctgtcg cgggagatcc gcctgtctgc ggaagaccgg ttaaaaaccg gagccgtgcg
    30601 agtggttgtc gcgacggctt cgctggaact cggcatcgat gtcgggacgg tggatctcgt
    30661 ttgccagatc ggatcgcctc gctcaatcgc aacgtgtttg cagcgtgtcg gccgtgccgg
    30721 ccattgggtt catgccatcc cgaagggccg cctctttgcc acgacgcgtg acgagttgat
    30781 cgaatgtgcc gcgttgatcc gttcgatcag agctggtgtg ctagaccaca ttgaggtgcc
    30841 gcccgcacca cttgatgtcc tggcgcaaca gatcgtagcg gcatcggcca ctcaggcctg
    30901 ggatgagacg gagctgtata agttgtgttg ccgggccatg ccctttcgtg atctcacccg
    30961 cgagaccttc gacgcggtga ttgccatgct ggccgacgga tttgcgacca gtcggggccg
    31021 gggccgagcc tatgtgcatc acgaccgcat caaccatcag attcgcgggc gccgcggggc
    31081 cagattggcc gctattactt cgggcggcgc cattcccgac acagcaaact acgcagtcat
    31141 tgccgaaccg gacggcacgg tggtgggatc cgtcgacgag gacttcgccg tcgagagtct
    31201 ggcgggagac attattctat tggggaacac gtcctggcgc atcaagggcg tcgaaaccgg
    31261 caagatgcgt gtcgaagatg cgcagggtgc accgccgacc attccgttct ggcgcgggga
    31321 agcgccggca cgcacggcgg acttgtcggc agaagttgcg cgcctcagag ccgatctcga
    31381 ccatcgtctc gatccgaatg tgccggcgcc tcctccttcc gcgccgccgg tgcaatggct
    31441 caaacaggaa tgcggtctcg atcagcgggg ggcggagcaa gcggttcaat atatcctggc
    31501 cggcaaatcc gttctgggga cggtgcccac gcaacacacg atcgtggcgg aacgattctt
    31561 cgatgaaagc ggggggatgc agctggtcat ccatgccccg ttcggcggca gggtgaaccg
    31621 cgcctggggg ctggccctgc ggaaacgctt ttgcgtgacc ttcgattttg aactgcaagc
    31681 cgcggcgacg gatgagggga tcgtactgtc gctgggcgaa aagcacagtt ttccgctcga
    31741 gacggttttc gcctttctga acgtcaagac tctgcgcgac gtgttgactc aggccgtgct
    31801 gcaggcgccg atgttcatga cacggtggcg atggaatgcg tcccgagccc tggcgctgct
    31861 ccgatttgcc ggagggaagc gggtgccgcc tcagattcaa cgtatgcgcg ccgaagatct
    31921 cctcgccgcc gtgttcccgg atgccatcgc ctgccaggac aatttccaag gagaacgcac
    31981 ggagcgccag attcctgacc acccgttggc gcaagagacg atccgggatt gcctgacgga
    32041 agcgatggac attgacgggt tagcggcggt gctgaaccga atcgaatccg gcgcgattgc
    32101 ctgcgtcgct gtcgatacgc cgatgccgtc cgctttttgc cacgagattt tgaatgccaa
    32161 cccttatgcg tatctcgacg atgcgccgct cgaagagcgg cgggcacgag ccgtggatat
    32221 gcggcgcacg cttccggctg cactggccgg ggagatgggc gcgttggacc agtcggccat
    32281 cgatcaggtc agagaagagt cctggcctga tgtgcgtgat gcagaggaat tgcacgatgc
    32341 gctgttgacg ctcggctggg tgccctgcgc ctgtatgccg ggatgggact tgctcgtgcc
    32401 gaggctcgag gtcgcaggcc gggtcgccac gctgtggcgg ggtgataaca aacagggatg
    32461 ggtggccgcc gagaatcatc agtacggggg cctgctcttt ccggataccc ggatcgatcc
    32521 ggaatcggca ccgactcatg agcctttgct ggaacgggaa gaggtgttgc agcgcattgt
    32581 cttaggctgg atggaaagtg tggggccggt tacggccgct gatctggctg cgcgtctggg
    32641 cctgacggtg ccggatgtcg acggcgcgat gttgcgactc gaagcgcagg gccacgtgct
    32701 tcgagggcgg ttttcaacgc aggtgtccca caccacggat ggggtggtgg aatggtgtca
    32761 tcggcggctg ttggccagaa ttcaccgcct cacggtcgga cggttacgca aggagattga
    32821 acctgtcact gccgccgagt tcatgcggtt tttattccag tggcagcacg cgtcaccggg
    32881 ggcgcgtctt catggagagg ccggactctt ggaggtggcg aagcagctcg gagggtttga
    32941 agctgccgca tcggcctggg aggcgcagat tctccgggtt cgtttggcca agtatcaacc
    33001 ggaatggctg gaccggctct gtttgggcgg cgcgctgatg tgggggcgta tcacgccgca
    33061 tccgcggctc atgcaggagc tcgccctgtt gccggggcgg cgtgtggttc cgacgcgggt
    33121 cgcgccggtc agtctgtttg cgcgagaaga tgctccggtg ctgttggagg cgactggcga
    33181 ggatttggcc cgattggatc tgtcctccaa actcagcgtc tcggctcagg ccattcgcca
    33241 ttgtctgcag cagcgtggtg cgagcttttt cagcgagctg ctgcatggtg cccgtttgtt
    33301 ggcatcggaa gtggaggatg ggctctggga attggtcgcg gccggcctgg tcacggctga
    33361 cgggttcgac aatctgcgag cgctcatcga tccgcgccgc cgtcgggcgg aggcgtccga
    33421 tcggaatcgc cggcctcgcc atgtcggtgg acgctggtcg cttttgaggc cggccgtcgg
    33481 acaatcacag accggtcctc aggccgcgac gaccttgcga gcatcgtctt cgtcggccca
    33541 tgttgtgggt tcctcagaaa gggcgcaggc caccgaacgt attgcgcggc aactgctgca
    33601 gcgatatggc gtggtattcc gggatctgtt ggcgcgcgaa tcgatcgtct cttcctggcg
    33661 ggatctgttg gtctgttacc ggcgcctgga atcgacgggg gagctacgcg gggggcggtt
    33721 cgtcagcggg ttcacgggag aacagttcgc cttgcccgag gcgctggaag cattgcgggc
    33781 attgaaaaag cgtccaggta ccgccaccca gcaggagatc aaaatttcgg ccgccgatcc
    33841 gttgaacctg gccgggatca ttctgccggg acctcgtatc gcagcggtcc cgtcgaactt
    33901 tgtggtgttt cgcgagggcg tcgtcattcg caccgtgacc gggagaagtg cgactgatcg
    33961 gcaggagccg cccatcctcg aagtggcaca acgggatctg cgatcctgat cagataagcg
    34021 gcgcggggat ggcgagcaac gggcatcgcg ctccgcgcaa gacccgttcc gtggtgctgc
    34081 cgcgtaacat gtcgagcaag ctgtcctgcc ctttggttgc catcacaatc acatccacat
    34141 cgaattcggc acctgccgcg agaatccatt cgacgggatc gccctttcca aacaactgat
    34201 tccaggacca gtccgccttc tgcggaagcg ccagtgtctc aacatcggct tccgcgcctg
    34261 catggataag cgtcatcgtg accggtggct tgctcaattg ggacaccagc acggtcgccg
    34321 catcgatggc gggttgagag gggggatggc tcgagatcgg cagcagcacg cgatgcagtg
    34381 aggtttcgcc ggtggtgcga gagacaaatc ccgcgacgtt ggatgggacg aacagcgtgg
    34441 tgacatgcat ttcgcgcgaa acgggctcag cgaccgcgtg atgaatccat ccggcaaacc
    34501 cttcgtgctt gtgcgtcgcc agaaccatga gatcggttgg tgtcgcggtc aaatgatgca
    34561 tgatggcctg cttggcgtcg gccgccaggg cgcgaacttt tctgatccgg atgccaagcg
    34621 tggtcacatc gcttttggaa ctggattccg gaaggagtcc ccactgcgcg agggtcggac
    34681 ggatgcgggg aaaatcctcg aacccttccg gcgagacgtc gggatccaca tgcatgatgg
    34741 tcagctcggc gcggaagacc aacgccagtt tgagcgcgtg gacgaatgcc acctgactgt
    34801 cctgcgaaaa atccgtgggg tgaaagatcc gatggatcga gaggggattg cgcggcgcgt
    34861 tcatgtccgt atcgaactcc ggtgaggtgc aatctgcctg tgctgcccgg tgatcggtct
    34921 gtgtcgtcag cggtgcgcgg tttgtaaagc cttgaccagc tcggtggctg acgaagagcc
    34981 ggcctggctc cagcggctga acgcagcctg cgccgtcggt tgaaacacag ccgcatccgg
    35041 tagatgggcg agggcgtcca acgacgccag atattcgccg tgaccccgcg ccgcatcagc
    35101 ttccaaattg tctgcattat acgcggtgaa ggcggctacc ttgtgctcag atttcagcag
    35161 gccgtcttca ttccaccaga tgcgcccgga cgtggtgccg gtgatattcg atgtggtgtc
    35221 ggtggtctct ttaaaggtgg ccttgaacga acaggctgag agcaacgcca ggagtgaaag
    35281 tccgctggct gcggcgatga gcgaacgacg gtgtccagtc atacgtagtg ctcctttcat
    35341 gcggccacat ggagtgatgg tggccgacta tagcatagtc gacacggaaa tgagcctagg
    35401 ccggcccttg gtcgtcagag gttgagtctg ttcgaaggag gtaacggttg acaatatccc
    35461 caggcatcag cacaatcgcc gggtccttga tggggcacga attcgggcga ggcggcctgg
    35521 tcgctgtgat gagccaggag cagacgcacc ccggtatcac aaggaggggc gacgatgaag
    35581 gtaggcatgg gcttgtgtgt gatcgcagga atcctctgtg cagcgccatt ggtgcgggcc
    35641 gagacggttc cgctgaagcc gggtgagtat caggtgacag ccgtgaccga gagcagcagc
    35701 ggggaagccg gcaagccgga cacccatacc cgatgtgtga aggaagaaca tctggcgaac
    35761 ccggatgcgg tgtttaatta ttatgcctta aacggattca aacccaatcc ggccaacaag
    35821 gtcatgaacg tgtcgatgca tggcgggacg gtcagttacg atattgaagg cctctatgcg
    35881 atgacccgcg tcgaaggcac ggtctcgacc accggttttt ctgtggtccg caaagcgacc
    35941 cctaagggcg acaaggccct gtcggtgacg atgaaggtcg atggcaaacg cacgggcgat
    36001 tgcgcgacga agtaagttcc tgcccgatat cgcatctgca tacagcgaag gtggcgtgac
    36061 ggaggccggc gttccggcct ccggtttctc tcgctgctag ttgtcccaca aacgctgata
    36121 ccacttcttc tccttcccgg ccggaagaga tgccaatttc atggtgtggc ggatctcgcc
    36181 gatattccac ccggtcagcg aggcgagtgt ctgcgcttcc tgctcgtatc gctcgcgtaa
    36241 ttgttggcgg tacgcggtgg cagccgcaca gtcttctgtg ccggtccacg gatggcgcag
    36301 gatgtagcgc gcctgatagt tgccacgatc cgaggtttcc tgaaacatca gatcttcggg
    36361 aaaatgcgcg gcgtcgtagc ggacgtgcag cctcgtgaga aagacgttct gggccatcgg
    36421 caggctcttg cccatccggc cgctgctctc ctgccaaaac acgccgagac tgcgcaattc
    36481 ctcagccgac agcgggtcgg ccgcacaggg atcacaccag ttcatgtccc aggcatattc
    36541 catgaagatc ccgcgttcgc tttcccgctt cacctgctgg ctgaagaggt cgcggtagaa
    36601 gtcgccgaac ttttccttca cgaacagtgg aacctcctgc gcctccggta accgcaccgt
    36661 ccggtagttt gtggtttcga cacggccttg cttggtgagg aagtagagga acaattcctg
    36721 cgcaccgtcg gcgttgaccg tgccgagccg gatcggcagc atgaacttgg gcgattcgaa
    36781 cgcgatctgc agcggccgga gatacgtgag gccaagcttg gcttgttcac cgaggttgac
    36841 cttcgcgacg aagaatttca tgccctgttt gagataactc tgcaggactg ccgaggcgcc
    36901 ttgtgggatg cggtagccgt tctcggtcaa ccagatttcc aggccgctgc tttccttgcc
    36961 cgagagaatg aggatgtcgt attcaccgac cgtatactgc gcctccacgg ttacgcccag
    37021 ggccttgtca cgttcaggtg gcgcggctga cggtgccacg ctcttcatgg cgtccatgct
    37081 gcggcgttcc atcagctcat agcggaggca gggattctga tcgaagtatt ccaccagccg
    37141 aggcgccgag taatccgcta gatgtttcag cagggccgga tcgcccacat ggatctgctc
    37201 cttctccaga acagtcggga ccggcaccac cagcgcgaac tccttcacct cgcccttgaa
    37261 gtcattggcc atcgtgatca cggtcttgtc gtcgtgccgc gcgatggcca cctcggaggc
    37321 cttgttgaac agtttcgtat cggccttacc aacatagaac ccgcagaaag ctaaggcgtc
    37381 gccaccccag gcgagcaggc tcagggtgaa taatactgac ggaatgatgg cacgtcgcat
    37441 agaaacctcc ttggttgatg acagaacagt ggagagagtg cggactggta ttggagccgg
    37501 gtgaggagag ccaccggttg aagcgtgcgc ccactggtag cgcgagccgg ggagtacatg
    37561 atcgataacc ggcaccaacg gcgcgcaggc aatgagtccc caaagcggcc cgttgggctt
    37621 gaatagtccg aattgcacat agagcgcggt gaaagacacg aggagtgcgt agaccatacg
    37681 tccgatgcgt gaatccggcg tggtcttcgg gtccgagatc atgaagaagg caaagatgag
    37741 cagcgtgccg ctctcgatct gatggagtgg aatcgtgagg ggatcaccga gtcgaactgc
    37801 ccgggcgaac aggagcccga cataacaggc gaggaacgcc agcgtgacat cggcgcgtgc
    37861 ggcgcgggtg accaccagac tcccgaggca ggctatgaga aaggcgagcc aggcggtctg
    37921 cccccattgc cccggcgaga tccatcccag cccgctgccg agcatgacgg tcaaggccag
    37981 attggtcgga ttgaagaggt gcttgtcatg ccagcgaagg acaaacttgc tgccgatggc
    38041 gaggaaggcc gccaatgcgg cgaccgcgag atcatcggta cgcaggagga ggcacagtga
    38101 cagtgaagag atcagtgcgc tcttggcatc gaatgccgga aggttgacga ggatggtccc
    38161 gacatattga gtgagcaatg cggtgccgat cgtcaccaca atctgccgga tcgacagatc
    38221 gaagtggagc cagcacagac catagatgag gagagtgccc aggctggcga tctggtagta
    38281 gcggggatcc tgccgagatg ctgacgggtc aggttcagga ttggcgtgct gctgctccat
    38341 aactcctcct ttacggaggg tatggcatga ctcggaaaat cctttcagcg ggccatctgc
    38401 ctggctctag ggatgtcccc cattgagtag atgggcgtaa tccattagca tgaacttgaa
    38461 tccatcgttc agccgaggtg atgccgtgcc catccaggtt attgttctta tagggttttt
    38521 gtctctgctc cccggctgct cgctcgaaca agagttgtcc agaacgccca ggacggctgt
    38581 cgagcaagtg ctgctgacgc aggctgtgaa tcaagcgctc acgaatctta ccgtgcaatt
    38641 gcctgtcggt gtgaatgttg agctcgatgc gaccggtctg gagagtgacc ggtcccgact
    38701 tcgcatgacg aattcggacc tgggctcgtt gaacagtccc aaccgggaca ttctgtacat
    38761 cagagatacg gtcgcggctg aattgggacg cagagggtat ctggtgcggg cgcgcgacac
    38821 ggagtcgccc tatcttgtgc gggtcatggc ggaatcgttc gggacgatgc aggggatcac
    38881 gttcttcggc atgccgccgg tccagagtgt gctgattcca ttcgcgcttc cggaattgac
    38941 gctctacaaa caacaaaacc aaagcgggta tgccagactc catctggata tttacgacaa
    39001 tcgcacgggc gagtttctcg gttcttccgc cactctcgtg ggtcgaacgt tttacaacca
    39061 atacacgatg ttattctttc tcacctggaa ccgcaccgat atcgacgcgc cgccgtgata
    39121 cgcgagagcc acccttcctt gcaatccttc gagtataatc cggcccatgc ttgaactgct
    39181 cctcgtgctg gcgagcctgg tggtgatcgg gctgacaggc ctcctgacgg ttgtcgccac
    39241 tccgccccga atggttgagc tcggcctttg ggcgctggcc ctcggcttgc tcatcggtat
    39301 cccaacgggg tggtggtatc acgtggtgct ctatcgagcc ttgtccgcgc gcatggcgct
    39361 gccgcgtcgg tggtggcaaa gaccggtaga attgcatccg ttactgcagc cggatgaatt
    39421 tcgccgggtg cgtccctggt ttgtggcggg tgcactgggt tttgttttgt gcttcaccgg
    39481 gggcgtggcg gcgatagccg gaatgctggt gatgcggttc tacccgtgat gccgacagtc
    39541 ggcaatcctc acattactga acgaccggta tctcgacggc gagctgggcg ctggtggatg
    39601 gatcctggct cacaacgtag gtcgcctgtt cctgaacgcc tgcggttgtg ccgggagaga
    39661 cagcttcgat gagcagtgac gcggagaatc ggtccagcat accgacttcc tgcatcgtca
    39721 acggtccgaa gggtttcgaa gatagccgga taatgagcgt gaccagcccg ttttcagcgg
    39781 gaggcggtat gggaatgtcg gtccgtttcc caggctggag tttgagggaa atcttgccgg
    39841 tttcctgcgg cggccaccag agcctggtgc cggcagagcc aaggttttgg agcagctgta
    39901 cgtacgattc ctgcgtcgcc tccacggtga gacggacggg gtcgctgctt cgcgcaacca
    39961 tcgctgccgt gatttcctga gtccggccat cggttcccct cgtcacaaag ctgtagcgaa
    40021 ggcccaacgg tttcgcctgg ccgaggctgg ggctcgattg ctcgccataa aagagggcgc
    40081 gggcgctctt cttgggggct ggagcaccag ccgccgaaaa tccggccggc gcttgcaaga
    40141 gaggcggcgc tgccgatggt tgaggcgctg ttgaaggtgg tgcgggggca gcaagcgttc
    40201 ggtcggctga agggggcgtg ccggtcgatt tcttttcggc agccgccatc ggggcgttgt
    40261 tgctggattc atcgcgctca cgtcgagggg gagccgtatc agtcgaagat ttggccgcag
    40321 actgttccga cgccctgccc gcaagaggct gctcgcgttt ggcgcgcgtg tcggtgcgtc
    40381 tgttttcctt ggccgcgtcg gcaggttcca tggcttgcgg gtccggcgta gcggcagact
    40441 gtggcgccgg catcgacggt tgtacacgtg gcatcggcgg tgcggccggt ttaacctcct
    40501 cagtcacgat ggattgtctc gctcggtcga ggctctcttg atagattctg gtcccgaatg
    40561 cgatggcaaa gaccgcagcc gccaaccctc ctgcccaggc gagccctgcc ggtttcttca
    40621 gccagcccca ccaggtgtct gttccgccgg tagcggtggg gcttgtgtgc tgcaatgcct
    40681 ggaggagccg ccggcgaaca tccggattcg ccagcaactc tttcaacgcc tgttcatcgg
    40741 ccagggcagt gaagagctgt tgatcgtgca aggccgcggc atagagctgc ttgcgttcct
    40801 ccggcgtgag ggtattcgct gcaaagccgc ctaagaggtg ttccaattcg tgatcagcca
    40861 tgctcgatac ctgtcacaac gcgatctctg atggagtgag cacccatcat cattcccatg
    40921 tcccgcccat cagactcaat aactgtttcc ggcaacgcag gtcccaggtg taaatggtat
    40981 tgatcgacgc ctgccccatg agcgtttgaa tttcagggaa actgttcccc tccagcttcc
    41041 atttgaacag ttggcggcag cggtctccga gctgtcccag agcagccatc aagcgatcga
    41101 cacgctgctt ctgatccaat tgcgaggccg gatcggtgcc gggatcggcc gacggcaggt
    41161 catcgacgga gtggtcatta tactcgcccc gccgcagtga ttttcgatgg gcatccagca
    41221 ttttgaagcg cagcacttga aaggccaggg gcaccagttc ggtcaattca gtcacgcgga
    41281 catatttttc atgcaggagc atcagcacct cttgcgtgag atcctctgcc acatccttct
    41341 gaaggcgtga tgtcgcgaag gtcagaatcc tttcgcgcag gtgggtgaga atctcgtctc
    41401 gcgtcacggc ggtcgtgctc agtgaggtgt ctgtccggat gcatggggaa tgagatcccc
    41461 gatcgaccgg aaccctacct gaagtccttg gcacacgtcc acctgccgat cgaagcggtt
    41521 cttcgtcagg atcagttgtc gcaaccttcc catcgcgacc cgtccccatg ccgccaggtg
    41581 aaagacaggc aacggataat cggttccgaa cagcagacgt tcatggacct gcggatagtt
    41641 ccggaggtgc agcagcatcc gtaaacggtt gggtaaggtg agggcggaaa tatccgcata
    41701 aaagtgcgga taacgctgca ccagatcatg caaggtggga agaaacttct catagaggat
    41761 caggccgtaa ctgcacgcat gcgccgcaat gaccgtcacg ccctcatcca atgcgacgcg
    41821 aagccgatca ggctctccca ctgactggtc cttgccgatc aagctgaatt catagccgac
    41881 atgactgaga aacggcaact tccgttccgc cagcgctcga taaaaggggg tgtatgtctt
    41941 gttcgccgga tcgaactgct gcgcattcgc cagcactttc actaacacag caccggcatc
    42001 cgcgcagcga tgcacttcct cgatggcatc gcgccgttgg gggttaatgg atacgccggc
    42061 cagcaattca tcgggatgcg cctgggccgt tttcaggaca tagtcgttcc cgatgagaaa
    42121 atcggtgttc gcctggttga gccggccgtt ctgatcatac gcaccgtcca tgccgaggag
    42181 cacggccttg tgcacgtggc gtgaggctct caattcagtc aggagatccg cgagatattt
    42241 ctggttcgct tcacgcggat gcttcggcga gaggccatgt ttccagagca ggaagcgaaa
    42301 cagcgggctg cgtagcgttt ttggagaaat gtagcatccg ttgtcgccgt ccggcagcgc
    42361 cgcgagatga acgtggcaat cgatcagcgt ttttgtgacc ggtcttgtca tgggttcatc
    42421 aaaaactggt ggctcctcgg ccgtcacctg gccggaacct ccgcgaggat ggttcacgtt
    42481 cccgatatgt tgagtcgttc cattgccatc cgcttgaggg cgcggagatc caatttgccc
    42541 gttccaagaa tcggaagcgc ttcgaccttg aagcaacggc tatgggacgg cagaaacaaa
    42601 ttcggaaggc cggcggcttg cgccttcgcc aagatgtgcg gaatccgttc ttcggcgagc
    42661 gtatggagga cagccagctg ttcgcctttt cgctcgtcgg gcacaccggt gactgcgcag
    42721 acttgtaatt cttcccctga ggcctgttgc agcgcgtctt caaccaaccg atgcggcacc
    42781 atttctccgc cgatcttgga aaaacgtgac agccgatcgg tgatcgtcag gaagccgtca
    42841 tcgtccagcg tcgcgatgtc gcctgtaata taccatccgt cgcgcatggc ctgagctgtc
    42901 agatcctcgc gccctaagta gccgttcatg acgttcgggc ctttgaccag caacatgccg
    42961 ggcatgccgg gcggaaggat ggcgtcagtc tcgggatcga cgatacgaac ggacacgccg
    43021 ggaagcggct ggccgacggt cccgcgccgc gaggccggtt ggaaaaatcc tgccgctctg
    43081 aaatccggac agttcacggc aatcacgggc gcgcactccg tcacgccgta cccctcgatc
    43141 gggccgatgc cgaaccggtc ctggaacgat tggcagagac gcagcggcaa tttttccgcg
    43201 ccggtcagca cgactcgcag cgtgctgaat tgttcgggcg tacagcggcg ctggtagagc
    43261 tgtaaaaacg tgggcgtaca gacgagaaat gtgaggcgat atttggcgca cagttctcca
    43321 acggccgtga catcgagggg agaaggatgg aacacgctgg ccgcgccgtt gagcgtgaca
    43381 taccagaaca cgaggtagcc gaacgagtgg aatagcggga gaatgccgag gatgcgatct
    43441 tccgggtcca ggggaagcac ttgggagacg gcctgcacat tggcgtcgat gctgaagtgc
    43501 gtgagcatca cacctttggg ttcgcctgtg ctgccgctac tgaagatgat ggtggcgaga
    43561 tcatccatgg tcacccgccg cgtctgtccg caggacgatt caatgagccg gagcggagcg
    43621 aaaagcgcca gcgctgcggc gagcattttt tgcaggctgc cgatggtagc accgatgtct
    43681 tccagccaca ggatcgttgg cccgtcgggg acttcgagct tggctttctc gataaacttc
    43741 cggctcgtga cgatggtacg cagttgtgcc tggcggacgg ccgattcgag gccggccttc
    43801 ccgacagtgt aattgaggtt gacgctgctg cgaccggcga gtgccgcggc gaccgtcgtc
    43861 agtgcccccg cgacagtcgg cggcagcagc aaacctacgg acggttgtcc ttgccagtgg
    43921 ggcgtcagcg cgcgcgccag ggcgatcgca ccgatcaaag cctggaggga agacacatgg
    43981 ggcttggttg cgtcggccat agcgaggcga aagggatgcc gacgcatggc gcggacaaag
    44041 gcggcatgca acgggcgtcg ggacgatttt cgccaatgcc aggccgtctc gccgagttcc
    44101 ctgacgagtc ggcggagctc atgcgccggt gtgccggcag gcacgggggc gccgaaagag
    44161 acggtcaccg gatagggtag ccgttccggc catttggtca caaaccgtcc tccgacaaaa
    44221 ctgaagatgc tcccccagac gcgatccaga tgcaccggga cgacgggcac ctcccggcct
    44281 ttcacgatcc gttcgaatcc ccggcggaac ggcagtaagt tgccggtccg tgtaatctga
    44341 ccttcgggga agatgcagac caggtcaccg tggtcgaggg cctggcccgc atcgcgcaag
    44401 gcccggagaa tgacgcgcgg gccgccatcg gaggcaatcg gaatgacgtt caacgcccgc
    44461 atgaacggtt tgaagaaggg aaggttcacg tagtgcgcgt cgacgacgaa gcggataggc
    44521 cggtccacgc tggcgatcag caaaaatcca tcgatgaatg aaatgtgatt ggggacaagc
    44581 agggcgccac ccgtgactgg tacgtgagtc tggtcgacga tacgcaaccg gtagatcgta
    44641 tgcgtcagca gaaccaggac gaggcgcagg aaggtttcgg gcatcagcca catggcccag
    44701 gccgtcccga tggtagtgag gccggctgtc gcgagaaaga tgcccacggt cgaaagtcct
    44761 acattcgcta gcacaccgcc gctgagtgag cccagcagaa tgccggtgaa gacgcagata
    44821 ttttccagcg cgatgaccga gccccggcgg tcgtgcggtg cgcgccactg caccagggca
    44881 ttgatgggaa tgaagatgag agcgctcgac atgcccaacg cgatcatcac gacgagggta
    44941 ccggtgaacg ccggcaccca ccagccgagc gtcaggagga aggtcgctac gcccgccgcc
    45001 cccaatggaa ccagcccgta ttccacgcga gagcgggaga gtcgtcccac cacgagggcg
    45061 cccaagccga tgccgaccga gattagggcc gaaggaacag tggcaagtgc atcggaaagg
    45121 cccagtacgg ctttggcgta gaccagcacg ttctgcacaa cgagactggc aatcgtccag
    45181 aagaacacgg cgcccgtgat ggccagccgc aacagccgat ccgcgcgtaa tgccgagagg
    45241 gcgccgcgca aggtgtcgaa gagtcccccg gcagcacgtg cagccggcac tggcggcaca
    45301 gcccgggctg cggcgaaacc gatcagcgcc aatatggtca gcgccagcgg agcaagccag
    45361 ggttggtttc cggcgccggc cagcaggaag cctcctgcag tggtgcccgt caaaatcgcc
    45421 aagaaggtga acaactccag aatactgttg ccccgcgcca gttgggcatg gggcagcaat
    45481 tcgggaagaa tgccgtattt agccggactg aacagcgcgc tatggacgcc catgcaggca
    45541 agcatgacga gagcccaggc acctccggtg ggatgagaca gcagggccag cgttgcaccg
    45601 gccatgagca gcacttccac ggccttcatg gtgatgatca cggtccgctt gctcagccgg
    45661 tcggcaaaaa atcccgccac gaaggaggtc aggaccaggg gcagggtaaa caccaccatg
    45721 gccagcgtgg tctgcgtttg cgaggcggct tcaagatcct gtccaggcgc aagggttgtg
    45781 gtgacggccc ggatgcccag gagggcgacc ataaatttcc aagcgttgtc gttgaaggct
    45841 ccgcaaaact gtgcgacgag caatccgcgc aacggccgcg cgggtggtgg tgaggaatcg
    45901 gactgcggat cgataggagc ctccttgcct ggcgaaacac aggcgcctgt caacggtcat
    45961 gagtccagtc tgctgaaacg tcctggaacg atgcaatgac ttaccgtggc ggcattggat
    46021 cggcgctctc caccggaagc ccttccagtg ccatgattcg taaggcattg gtcgtcgggc
    46081 agggacccgg cttgagacga tagtcgaagt gcagggcgcc ggccacgacg gtttcctgaa
    46141 aatgaacatt ggtgacagtc ggtaactgct tctccaactc agccagttcc agatcgtggg
    46201 tcgtgaccag tccgaatcca ttgcctccgg caagcgcggt aatcaaggcc ttccccccga
    46261 tgagtcgctc ccgattgttg gtgcctttga acacttcgtc gatcaaccac agcactggag
    46321 gtccttgtct gtctctcgtg ctgtcgagga tggttttcag gcgtttcact tcggcataaa
    46381 aaaacgaaag gccgccgtcg agagaatcat ccacgcggat gcaactgccg atacgtacca
    46441 gcgaccagcg aaaagccgtg gcacacacgg gagctcccgc ctgcgcgagg caggtgttga
    46501 tgccgatggt tctcagaaac gtgctcttgc cggacatgtt ggagccggtg accagaaaga
    46561 ttcggccccg cccttgcaac gtaacctggt tggccacgcg gaccgcggca ggaatgagtg
    46621 gatgcgccag cccttcggcc gcgagttccg gcgcgttgcc gttttcttga ccgtctgccc
    46681 cggcgtgatg cagcgtgggc cagagatagt tcgggtgcaa atgggcgaag gtggccaggg
    46741 acgcggcggc atccaaatca gcgagcaact cgaaccagag tggtgcgaca gaggcgatcc
    46801 ggtcctggag ttgttgcagg cgataggtat ggaagagatc ccacggaccg acggcattga
    46861 tgagatagtg gaccaaggga tgggcacgta cactgagccg gttcatcagg gaagcggcct
    46921 gtttcagtga acgcgacgga ctgctgtctt gttgcatcaa tggagcgcag agcttggcca
    46981 gatgcggggt gcttcggtag gagcgccgtt cgagatactg tagcacggca ctgagccgct
    47041 ccaattgtag gtgcaatgac tgggcatggt cgaagatttc ttccgaccgg ctgcggaccg
    47101 acaggaacag gaaggcgtac aacccgaatg acagcatcca atagttacca aggccggaaa
    47161 tcaagtcggc gagcagcagg atggccgtgg tgacggcaag agccgattcc gtcagcaaca
    47221 tcggcatgag tccagaatcg tccacgcgtt tctgtaacac cgcaagcagc cggcgcccgt
    47281 cgatgtcggc ttcctccacc gcctgtgcct ccaggaccag tcggtcacgg agcagcgaca
    47341 agggcgtcaa ttcccggatg agggcctgcc ggctcgacca tggtgcggca agaggaggct
    47401 gatccaagaa ccacgaggcg agacgttgcc gaccctgaga ggaaatgctg tggtcgatca
    47461 ggtgcagcag agagcgggga ccggtaaggt cgagatccct ggcatatcca tgccgttccg
    47521 gcacggtcac atcacgaagc ggaatctccg cccactgtaa gctgaggcgt gccagatgta
    47581 ctcgtttgat gccttgccag cgccggagtc gatgcaagcg atcttcgagc ctgttatgat
    47641 accaggccac gatcaggaac aggacgaagc cggacgcgag gacaagattg ccgaagagcg
    47701 tccagcctaa tttatgcgga atgatgctgc cgaggagggt cgcggcaaaa atcgtgagac
    47761 gagccgtggt aaaccgcgca ctgacgcggc gaccattcgt ttctagatga accgcccgcc
    47821 ggagtgcatg gacgagatgc tgctcacggg atggcttcaa ttctgctgac gtaactgggt
    47881 tcacaataat gctgacgata ctgggagtct gagatgacgt caacctccaa ggtagatcaa
    47941 tcttcttcct ccgattccgc cgcggtgcaa acaggggatt ggatacaagt tgatgtgcgt
    48001 acctcgctgg atgccggtga gctattggga atgctcaacg atcctgacgt gacgggggcc
    48061 tggcaagagg gtgacgaggt gcatctgtat tggcccgcgg gccgttgcgg gccggatacc
    48121 tggcaggggc tgaaacgtgc gctgactcaa cttggccatc cggacccgga tcacgcggtg
    48181 accatcaatc atttggccaa tcaggattgg aatgcacaat ggtcccggct ggtggaaccc
    48241 atcaagatcg ggcgggtcct gatcaggccg agctggagaa ccgtctcgct caattccgat
    48301 gagatcgaat tgatcatcga tcctaagcag gcattcggga ccggccatca tgcgacgaca
    48361 cagctgttga ttgaatggct gcaacaggct gtgcgaccgg acgatcgcgt gttggatgtg
    48421 gggaccggga gcggcatcct ggcgatggtg gccttacggc tcggagccac ggaggcgctc
    48481 ggggtggatt tcgatgccgt cgcggtggac tgtgctcgcg agtacgcgca ggtgaacggg
    48541 tttgacacgc gtctcacgct ggccgtggga caggctcagg ccccgcaagc ccatgatgcg
    48601 ttcgatccca ccctggtgct tgccaatctg gatcggcaga cgctcctgac atccgcagat
    48661 agcctctgcg cgtatgccgt ccgcggcgcc cgcctcttct tgtcgggact gttggccgag
    48721 cagcggtcgg aaattgaagc ggcctatgcc actcgcggag tctatatgaa ggccgttcgg
    48781 gagcgagacg gatggctcgc attggaggcg accgcgatgg aaacgtgcga gggcggtctc
    48841 tgttcctgat gcggccatga cgcgatcggc gactccatat gtgcatcaga tcagcgtttc
    48901 cgatggtgga gtgccgaagc tggccgtccc ctcggcgagg atcaccatcg acggactggc
    48961 cggcgaccgg cagcgcaatc gaaagtatca cggaggaaaa gatcgggccg tctgcctgtt
    49021 ctcgctggaa cgcatcgaag cgttacgcgc tgaggggcat acgattgggc cgggctcgtc
    49081 cggtgaaaac ctcacggtag ccggtctcga ttggcagcac atggcgccgg gtgaccaact
    49141 caccatcggc gagcatgtcc ggcttgaatt gaccagttac accacgccgt gccgcttgaa
    49201 tgccccttgg ttcaaggatg aagattttcg tcgaatcgcg caggaggtgc atcccggatg
    49261 gagccgcctc tacgcgcgag tgctcaatga gggcgtggtg aagccggggg atgttgtggt
    49321 agtcgacgcc tgtcctgggg agcggtgagt gatcttgatc cacatgtagg aacttatgat
    49381 gaagcgagta cttgaaccgg aattgatgga tgatgtggcg caagctctcg cctatgccaa
    49441 ggcggatttt gccgaggaga accagagctt tgtcgaccgc tttcgtgaat attttcccgc
    49501 ctgggacggc ggccatgtgg ttgatctcgg atgcgggcct ggcgatatcc cgattcggtt
    49561 tctccgcgcc tatccacatg cgcgagtgac cgccgtcgat gcgagccgtc ccatgctcga
    49621 tctggcggcg gacgccattg ccggagcagg gttgacggat cacatcaccc ttcgttgcga
    49681 gcggtttcag tcgctcgtgt tgccggaaca ggccgacgcg ctcctgtcca acagccttct
    49741 gcaccatgtg ccgaacccgc ttcagttctg gtttcggctg aagcagctgg caaagccggg
    49801 cgcgtgcatt ttggtcatgg atctattgcg gcctgactct cctgaatccg cccaggcgtt
    49861 ggtagaacag tatgctgccg atgaagatcc gattctgaag cgggattttt atcactcatt
    49921 gctcgcggcc ttcaccgaag acgacgtggc ggcgcaactt gcggaaatga atttatcgcg
    49981 cctcctcatc gatgtgcctg acgatcgtca ctgggtagtg ggcggaatca tcccctgact
    50041 gcctgttcga cacaagagct ggccgcgagg gctcacgtgc acgcctctat gagcggtgtt
    50101 tgtccagcca gatccatctt cattgcgacc ctgcgctgcg tgcactctgc gttgctcggc
    50161 tgcctgttgg ctatggccct gttgtacccc gctgaatcta ctgccgggat tcttgaacag
    50221 ttgcgtaagc cgcgcccgag ttcggaactg caggtccact ccgacgtacc catgatcatg
    50281 atccccgaag gagtcttccg gatgggtgcc gatggaacgg acgccttgga ggatgagaag
    50341 ccacaacatg acgtgtggct cagccggttt gagatcgacc gtcatgaggt gacgaccgga
    50401 cactacgccg aatttctcgc cgccacgaag cgaccggctc cctggcaatg ggagtcactc
    50461 gatctgtcac agcacggcga ccgtccggtc ataggcgtca gctggttcga tgcggacgcc
    50521 tattgtcgat ggcgaggcac acgtcttccg acggaagcgg agtgggaaaa agcggcacga
    50581 gggaccgatg gacggttatt tccctggggc aatcacagcc cgcaagagga aacggcgaat
    50641 ttcggattag gggccaggtt cagctacagc caggtgctgg ctcccgtaga gcgctacgaa
    50701 caagggagaa gccccttcgg cctgtatcag atggcaggaa atgccgggga atgggtggcg
    50761 gattggtacg gggcacacta ttacgagaac ggtccgcgtc agaacccttc cggacctgat
    50821 gccggagcat ttcgcgtggt gaggggagga tcctggtccg acctgccgaa atatctcctg
    50881 acctatggcc ggttcaagtt gcccccggag actcgcaaca gttacaccgg atttcgatgt
    50941 gccagagacg gtggggtgct agcttcgccg tgagccgggc gcccatgcgc cccagctcac
    51001 ggtttctcgt tcggtctaga acagactctt actgacttcc gcagatttcg cactctcgtt
    51061 tcccgacttg tcaaaagccg agacagcaaa gaagtaggtg gctccgaggg gcaggttcgg
    51121 tacggtgaag ctggtgccgt ttgtcacctc gaatggtccc acgactccgt aacttcctga
    51181 tttcgttccc acatagatgc ggtagccggc caggtcagac tccgtattgg cgttccagct
    51241 taccgtcgcg ctggcagtct tgggcgcggt gcttgaggcg gacgacgtcg gggtcggcgt
    51301 cgtggtcaca gggactggtg acggagggct cggaggcggc gggggcggag aggccaccgt
    51361 tggttgtgtc ggtgtcgtcg gggtgctgga ggctgtttga cccgcggcga ccgtaaaggt
    51421 cactggaatg cggagcgtat tggcgaagtt attgggacca gattcaacga tgtacacgac
    51481 tcccgaatag gtgcctgccg ccaggccagc cgtttgagcg gtgatgacca gttgatcgct
    51541 ttcggtcgta atggtctgcg tgctgccata gggcggattc atccagatcc atccctggtt
    51601 cgtgctgaga tagtacgcgt gttggtcggt tccggttttg cggagcgtca aggtgccgac
    51661 gttattggcg ctcgtcaggc tcaaggagga cggggtcacc tgaatcggcc ccgtggcaac
    51721 cgtgactggt gctggcgcag gtggggccgg agctggaggc ggtggtacga ccgcgggtgc
    51781 cggcggcggg ggcggtgcca ggacgactgg tttcggcgtc ggaacgatgg ccgggggaac
    51841 tgccgcgggg ggcggaggcg gcggtgccac ggccgatgcc gtcaccgtga gggtgaccgg
    51901 gatgcggagc atgttctgga agttattcgg tccggattgg acgacataca cgacggccga
    51961 gtaggttccg gccgcaagat tggccgtttg ggccgtgatc accagctgat cggtttccgt
    52021 cgtaatggtt tgcgtgctgc catagggcgg attcatccag acccacccct ggttcgtgct
    52081 gagataatag ctgtgttgat cggtaccgcc cttccgcagt gagagggttc caacggcggt
    52141 ttgccccttg acggcactca acgccaacgc agccgggctc gacgtgatgg ccgttccggt
    52201 taccaccggc gccacgacag gagtcggagc cggaggagga ggcacggcga ccgggctggg
    52261 cgtcgggata atggccggtg ggacagccgc aggaggcgga ggcggcggtg gtgtcactgc
    52321 cgtcgccgtg acggtgaggg tgactgggat gcggagcatg ttggtgaagt tgttcgggcc
    52381 tgaatcgacg atgtacacca cggcggagtg ggttccggcc gcaagattgg ccgtttgggc
    52441 cgtgatcacc agctgatcgg tttccgtcgt aatggtttgc gtgctgccat agggcgggtt
    52501 catccagacc cacccctggt tcgtgctgag ataataacta tgttgatccg tgctggattt
    52561 tttcaggttg agggtgccga ccgccgtttg tcccttctgg gcgctgagga cgagggcagt
    52621 tggactggta aatatgggag ccgtgccgct gttctgggcc atgattgcca ccgcgtcagt
    52681 cgatgactgc tgcagcaggc tgagcgtggt gtctgcggca gcggcggttg ggggcaaggc
    52741 tgttgaacac agcgcggaag ataagcaacc ggcaacaccg ataaccaaca cactcttggg
    52801 cgtcttcatg atagttcctc cgaaattcca gacgctggat gagcaaccgg catgccagct
    52861 cgaaaattcg tgcgaacgtc agaaagccgc gtcacaagcc attttgcaga gaatggcgct
    52921 gtgcgatagt gttcgttatt ttttgctgtg caagttggag cagtgggtgc aggaaaatgc
    52981 cttcgatctt gttcgcggga gcgtctgtga agcaggcggc caggcgactc ggccgcttca
    53041 ttgtgtagtg ctcggggaat gagagagggt cacgccgcgg gaggcgccgc aatccaatcc
    53101 gtgagcaatg tcagcatcag ctgaaagtcg gaagggtttg taaaccggtg atcagcaccg
    53161 ggaaggattt ccaggtgctt ggggcctgcc agcgatgcat acagtcgttg gctttggtgc
    53221 agaggcacgt attcgtcatg atccccttga atgatcaggg ttggtgctgc aatggcacga
    53281 gccggttcgt aggcgatgcg gttgaggcaa tcctggtaga aggcatagtc gagggggagg
    53341 cgggaaggac ctccatgaag atccgggatt gtgtttgtac gttgccactc ctgcagccca
    53401 tcttccccca gctctaggcg cagctcttct ccgaaatcaa cgaccgggca tttaagtgcg
    53461 aggcaggcga gagggggaac atcctccggc gcggagttat gtagatcggt ccattcagaa
    53521 gccgcgagca gcgagacaag gccgccgaaa ctcgagccca cgagtgcgag tcgccgataa
    53581 ccccgggtca tggcatacgt taatgcagcg cgtgcctgag ccaccccgat agtggttgtc
    53641 agcttggcga agggcccatc gctgtcgcca tggccgaaac agtcgaatcg cagcgtggcg
    53701 atgccgcgtg ttttcaagag ttcagccagg gcttggttac tcgtgctgtt cttgtgagat
    53761 aaaaagccat ggcagagcac cgcgacagag tcggtgctct gtggtggtgt ggccagcacc
    53821 gccgcaatcc ggtggccggc ctgatcgtga aatgaaagcg cttcttccat agtggtgaag
    53881 tgatggcggt tatttcgccg ctccttcatg ggacggttga gcgccggtcg cctgtgcgag
    53941 tttgacggtg accatggtga agtgaaacag caacagtccc aagcttatcc aggtgctcgt
    54001 ttgcagccag ggcgaggaca ggggaagatt ccaggtcaat gaggcgacga gcaccaaccc
    54061 caaagatcca aaacttacgg tcgcaacctg ggccgcccgc caacggttca tgatgcgttc
    54121 aaggtcttcg cgataggttc cccgcttttt ctgattcgcg atccgcgatg tggccagcag
    54181 cgacggcaac gtgaaggaga gtccgccgac catgctttgc aggagaaaac cgaggaaggc
    54241 ggtgtgggtg taggccacca gatgcagcgt cccatagggc atggccggcg gtgtcgataa
    54301 cacgttgatc ccgaatgcca agccgatgaa ggtcataatc agcaagaagc tcaatgccgt
    54361 gaggagatgg tccgtggcgg cagagccggg ttgaccggcc tgactccatg tgcgcagcag
    54421 gttgatgcag cacagcgcca gcgcgatcag gagcacggtt cccgccgcca actggatatg
    54481 aacggaggac aacacgaatc ccgtgatcag cccggcggcg gaggccggca gaagcagcat
    54541 gaccgcctgg cccatcccgg ggctgtgcag cgggcgatgt accatcatcg ggagcgtcag
    54601 ttggatggtt ccgacggctc cgagtatgag gaacagcaaa aggcctgcat ggagatggcc
    54661 cagacggaga atcccgtgcc aggtgggata ccaggcgtcg gcgagcaggc ctcccagcac
    54721 catgctgccg aacaggccgg cgaagctgat gccgaaatag acatgtacca atggtgtcca
    54781 tcctgagcag gtccggagcg cagtcagcat atggcgggcc atggggacaa agagcgcggc
    54841 cagcaggaat cctgcggcca gggtcaaggt gggattccgg aaccaggctc cggcagcaaa
    54901 cccaacggcc gtaagattca tgctgagaag gagcaagcgg tgtgtcgttc gtttcccctc
    54961 atggccggac agatcatgtg ccgcgatcgc caggccggtc atcaattgga gaaccccgcc
    55021 gatcagcact ccgtggacgt gtaaaaggcg aaggccggag ggaagcgggc ctccccgtac
    55081 gatgccccca aatgcggcga gtcccaacag tgcggtcagc agcacccagc cccatccggc
    55141 gagcagaaac gacagtggcg atccaagccc tcgactcata gcctctaacc ctgattcaag
    55201 aagtaaaaat gattggtcgg tcccttgcca tgcccaatgg ccaggccatg tctgatggct
    55261 tcagtgagat aggtcttggc ggtttggacg gcatcagaga cacttttgcc tcgggcgaga
    55321 tgcgccgcga tggcagaggc aaaggtacat ccggtgccgt gcgtatgggg cgtgtcgatg
    55381 tattcaccct tgaagatgtt gaagaaccgt ccgtcataga gcagatcggt cccgcgctct
    55441 ttttgcagat ggcccccttt gatgaggaca ttggcgcaac cgaactgatg aatgactttg
    55501 gcggcacggc gggcatcggc caacgaagtg atctcgatcc ccgaaagctg ctgcgcttca
    55561 tgcacgttcg gcgtgacgag caaagccagc ggaaagagcg cgctcttgag ggtatcgatg
    55621 gcatccggct tcaacagcgc ctgcccgcct ttcgcaatca tgaccgggtc caccacgaga
    55681 tgtttcacct gctgaggctt caggagtttc acgaccgtcc ggataatctc tgcggaggag
    55741 agcatgccgg tcttcaccgc cgccacgtca aagtcgtcga agatggcatc gagttgagcg
    55801 gcgatgattg atgtgggcag ttcgaacacg tcggcgactt cctctgtgtt ctgtgcggtg
    55861 atggccgtga tgaccgacat ggcatagacg ccattggcgg acatggcctt cagatctgcc
    55921 tgaatgcctg cgccaccgcc tgaatcagaa ccagctatcg acaagacttg tttaatcatg
    55981 ggtaagttcc tgtgcaagta atgagacgtg gacctacggt gtggggggcg ttgattcctg
    56041 cgcggccggg gcgcctggct caacgaccgg cgcggaggca attttcaatc cgtccagggt
    56101 gatgatccga tcagccctgg gtgacgtttc atggtagtgc aacgtgatcg ggcctgtcgg
    56161 cggcttattg gtggccagga acgagaggct cgcacgctgc tgccgcttgg ggttcagctc
    56221 catcccgcgc gtacagaggc cttcacgatt ctgcgcgaca ttctgtttcc actgctcgcc
    56281 atgctcgtcc acaagatagg tgtcgagaag ctggcagccg atcttgaccg ggtgcgccgt
    56341 acggttggtg aagacgagat cgagaccgat gaggtcgtcc tgccgtgtca cgctgagaat
    56401 cgtgaatttg tacaagtcat tttcgtgagc gctgaggacc ggcgcactat ccgttaccac
    56461 ggccgccgtg gccggagccg gagcggctgc ctgtttcagc agggctgcca aggggccgga
    56521 tttcggtacg atggtccgtg aggcgccgac ggggtagacc gtatagggcc caatcagctt
    56581 ggcggtgacc tgaatgcctt cgggaatctc cagatacgcg ccggtgacgt agaggtctgc
    56641 gcgcagggct ttggcgactt tcttggcggc cttggcttgt gacgtatcga ggtgggtcag
    56701 ctggtgcttt tccatggtcg cgatcagcaa cttgcgatcg accactttga gctctccggc
    56761 cacaagcaga tgagttgcca gctcttcggc caggaattgc ccgatgggtg tcacgtctcc
    56821 cttgctgtcc acaaagtcca gcagtgcgag ccgcgacttt ttcattttga tggcctcagc
    56881 cgccacccct tcggcgagtt ctttgacact gtcctcatat ttcgaggcag ccagagaggt
    56941 ggaatggcag aggacaagca ggatgaggca gggtaagaga cgaatcatcg gcccccgtgt
    57001 acgatcgcgc gacgcatggc ccacattata ctcacgctgt cgatgctgtc cagcccgtgc
    57061 gcgtcacccc gacagtcggg gcagaaagat tttggccaat gcgcgtccca gcccgtatcc
    57121 gaacggcagc atcatcagca aaagaatcgg caagtagaaa taggcgagcg ctccctgcgc
    57181 atcgggatgg atgagcacgt cgacatggac ccaggcggcg atgagggcca tgctcagtcc
    57241 cgctgagaag aggccgagtg cccgccggta ggcaatcaag gcgttgttcg ccggggcggt
    57301 ccccaggtgg aacaggatga tcagggccag gatcacgaac ggcagcgccg tcagcacccc
    57361 cacgaagaaa aaattatagc cgggcgcaaa gaggtgcaag gtgaacgacc tccaggcccg
    57421 tggataggga atgtcgcgca ccaggatctc cacggtcagc atgatgatcc agggaagaag
    57481 caatccgccg aggaggctga tccagacccc caatcgcgcc atcatccgga ggcgaggcga
    57541 tgtttgccgc gggatatcgg tcaacgtggc agttccttgc tcaacggttc ggcgttgacg
    57601 accgccccgg cttcgatcgc gctcacggcc tcggcgatag cggcgcgaac tacgaggtcg
    57661 gaatcctggt gtcgttgcaa ggccggcagc gcttgtttgg caacagctcc cattcccccg
    57721 atgctttcgg cggccagata gcgaatcaga ggctgttcat cttccagcag cgcaaggacc
    57781 gggggcaagg catcatgggc ggccgggccc aattgtgcca gttggtgcaa cgcatagtcc
    57841 cgtgcagagg aatgtccgag catcatgccc aacgattcga tatgggctgc atccccggcc
    57901 ctcggtttgt ccaaggccgt acgtgcgagg gtggcgatgc ctttatccgg atcgttcagc
    57961 attggcgtca gaaccgccac agcatccggc gaagggggaa ccgtaaacgc aaattgggcg
    58021 accgccgtct ggcgcaccag cgacgaagaa tcgcggaggc cgtccacgag ggcggccgcg
    58081 atcgggagag acggaatgcc gatgctcgcc agggcgatga gcgcattgcg gcgtatgagt
    58141 gcatcggcat catgcgtgac ggccagcagg gccggtaccg ccggtttggc aatcggcccc
    58201 agactgccga tcaccgcgca ggctgtgcgg cgtagttgca catcgggatc ttgtagtctc
    58261 gggacgaaat gggtcatcac ccggcgagcc gccgtcaaat cgatccactt cagcgcggtg
    58321 gcggcggtgg tgttggcatg ctgactgccg tcctgcgtgg cctggctcag gagttgcgga
    58381 acggcggatc gcgctgccgg tccgacttgc cctaattgtt cggccgcgac aattcgtgtc
    58441 gacggatcat cgtccttgag tagctcgatg agggtcggga caacccgcgc tccggtcgaa
    58501 aaccagtacc acagccctag cacaccgagc agcagcacga gccccagcag atggagttgg
    58561 atctcgcgtg agctcagaac ggtcggggtg gatgcggcgt cagtcatatg ggattaaaga
    58621 gtcgcgtttc agacgatgcg gccagcctac cacaaacgtg gaataaatct gaaagcgtcg
    58681 gctactgaac atcccggaac aggcggatcg agcgacggtt ctgggtgaat caggtggagc
    58741 tatcctcctt tccactacag ggaaaatccg tccataacct aggttattac cctgtagcct
    58801 atagcggatg agaggattac cgtgacagta ggacaaccag gaatagagga ggtcattatg
    58861 cctgtttact tcctcatcgc attgacgatc ctgttttgtg ccatcgccat ctgggcgtcc
    58921 gtgactcagg agagtattcc aatgaggggt gaagaagaac ccgattggga tgtcgaaccg
    58981 cttaaccagt cccaggaata tcgcaagacc ggttagggcc aggtagaggc ctgttcggat
    59041 aaatcagaca ctacgcgtgt cagctctcta tcctaaatag gacaggaacg agtggtagga
    59101 ctgtacggtg tgtcccatgc taacggtcag agaggggctg tgtagcctgc agtgtcgtgc
    59161 ctgaacgaga gatcaatcgg agcggcgatt ctcttaggga catattccga gtggggggcg
    59221 acccctttat tgagaagtga gaatgctgcc gtttgggtgg aatcctatgc gcgtgcatag
    59281 ggaacagtga atattgaagg ctgaattcat tttcgatgtc tttcggaaaa tgatgcgagc
    59341 cattgcatcc cggatttata aaaggcactg aattcgcgta ctaaccaaga caccgagaaa
    59401 ttatggaatt tcatttcaga agaaagttta ttatgggcta acccgagagc ataaacgcag
    59461 ggctcgtccc ttccaatcaa tgttaaatct gagtgaacga aggagtgttt gaatgcattt
    59521 gaaatttcgt tgagagcttt catgactgga ttgtgagggt caaaaagcac tttaaggtct
    59581 tttgaaaggt tttgttgcgt agattcaagc gcggcaccga tacaatcaat cctaatttgg
    59641 cgcggatagt cccccgtttt ttcccactca tgtagacacc agatcattgc tatcaattcg
    59701 tcagccactc gtctcatgag atagacagcc tgttcgattg catactcgtg acgttggaac
    59761 aagttgactg aagttttctg ctccattgcc tgattccaat aatcgaaagt gtcgatcaat
    59821 ctacgattag cttcgtcgag tctctcgcac agctttctaa gtttcagttg aaagttgcca
    59881 tagggagaat ctggaggcaa ccagaatcca agacgggcat tgtagggttg atctgggctc
    59941 ttcccatttt cgatcagaac caccacgata tttcccccgc ttacgttcga attggggaaa
    60001 ctgatttttc tttttccttc ctcatgaggt ggcatagtct agttattcct tcaagctcct
    60061 gtcgcgtaag tacacagtag aaagccgata aattagggtt ccgctatgct ggaagtattg
    60121 ttatttcagc tacctttcag tggacgtgtg actggcgggc agcgatggcg acactcggaa
    60181 cgccctcaaa gcgtcagcag gacctcgttc gacggtgggg tgaaccgtcc tgcgttgcag
    60241 gtgacgcctg ttgttcgaag ctctgttcgt gcgagcacga acagagcaag ttcaggcgga
    60301 aaggatcacc tcactgccga acgctgctgc ggctttgttt ccggcgtgta gagtgccgcc
    60361 atcgctgccc gccccctcac accggccact tctcctcatt ccaggccatt tcccaaaaca
    60421 tccactcata cttcgaactg atcagaaacg cctgctccat ccgttttttt tcttcatgcc
    60481 cggctgttcg cgcccaggta tcgaccctgg cgcgcatcca ttcctgaact gcctcgaact
    60541 ccggtgacgc atagagcatc agccaatcgc ggtacgggtg ttttgccggc ggcgctccgt
    60601 tcttgagaaa atgcttgccg acgacacaat aaatccacgc gcaggggagc gccacgacgg
    60661 cgatttccgt cgccgtaccc gcttgggcca cggccagcat gtggcgggtg taggcatagt
    60721 tggtcggcgc catcggctcg ttcagcatct cttgcggcga aaggttccag cgtttgccgt
    60781 agttttcatg cagactgcgt tcgacggtga tggtttcttc tgccagcttg gcgaagcgaa
    60841 gcgccgattc ggagtccgga gctcgtaagg acccggcggc aaagacccga gcaaggtctg
    60901 cgagaaacag ggcgtcctgc aggatgtaat agcggaattt tctttccgac aaggtgccct
    60961 tgcctaatgc gaggacgaag gggtgcgtca gttgtgcatc ccacacgggt tgggccagct
    61021 tacgaagatg atttgaaaac gacatccggg tcctccttgc tcttatcgga gactattgaa
    61081 ttctcgatgg gcactcctca gttcaatgcc tgacatgggg cattgaggac tattgcggct
    61141 cgcgagacag gggcctgtca ggctcgcggt gtccagggtc tcgggagttg attgatgcca
    61201 tccagcgcgg cgacgcgata acattccgcg agggtggggt aattgaacac cgcatcgatg
    61261 aagtaatcga tctgtccttg aaaggccatc accgtctgcc cgatgtgaat cagttccgtc
    61321 gcaccgtcgc cgattgcatg cacgccgagc aattgacggg tcttattgtg aaagagcagc
    61381 ttcaacatgc cgatctcatc accgatgatc tggccgcggg cgatttcgcg gtagcgggcg
    61441 atgccgacgg cataggggac tccgtgtttg gtcaggtcgt cttcgttgcg gccgaccatc
    61501 gaaatctcgg gtatcgaata gatgccatag ggcatcaggt ccgattgcgt ctggtagggc
    61561 acgccaaacg catggcaagc ggcgtgacgg ccttgctgca tggacgtgga ggcgagcgcg
    61621 ggaaatccga tgatgtcacc ggccgcataa atatgaggaa tggatgtttg ataatgctcg
    61681 ttgaccgtga ggcgcccgcg ctcatctgct gcgagtccga tggcctcgag attaagcgtc
    61741 gcgctggcgc cggtacggcc gaccgaatac agcacggtgg aggcggcgat ttctttcccg
    61801 ctctttaagc ggacgatgac tagttctttg gagatcggct cgacagacac gacctcttcg
    61861 ttgaatcgaa ggacgactcc gatactgcgc atatggtact gcagcgcttc aatggtttcc
    61921 tggtcgacaa attccagcag gcgcggccgg cgctcgatga gcgtgacgtg gaggcccatc
    61981 gtggccagga tggaagcgta ttctgcgccg atcactccgc cgccgatgat ggtgatggac
    62041 ttggggaggt ccttcagctt caggaggccg tcggtatcga tgatcgtctg atcgtcgaag
    62101 ggaatgtggg cgggacgggc gggaaccgtg ccgcaggcga tgacgatgaa atccgccgtg
    62161 tgttccacgt gatcatcagc ccgctcaacg cgtacgcgat gcggatcgac aaaggaagcg
    62221 gtgccgtacc acaggtcgat attgttccgc gtcatctggt tctgaatgat ttcgatttca
    62281 cggttgatga cgtgattgga acggaaggtc agatccgcca tcgtgatgtc ctgtttgacg
    62341 cgataactgg cgccatacag actacgttga tggaaaccgg agagatagag ggccgcttct
    62401 cggagcgatt tgctggggat ggtcccggtg ttggtgcaga cgccgccgac aacccgtgtg
    62461 cgctcgacga tgccggcttt tttgccgagc ttggcggcct gaatcgccgc cttttgtcct
    62521 gccgggccgg ttccgatcac cagcagatcg taatgggcca tggatagtcc tcaacggccg
    62581 taagacaaga gtcagctggc cgtcaccagc ttacgcgcga accggaaggc atcctctagg
    62641 tccggcagtt gagctaattc cggggtgatc tgcagatagc gcaccttgtt gtctttgtcg
    62701 acaaccagca gggcacgact caggaggtga aggtctttca gcagaagccc atgggccttg
    62761 ccgaaatcgg cggcgcgaaa atcggacaga aaggtgacat tgctgatctt ggcttcttct
    62821 gcgaatcgtt tttgcgcgaa cggcgtgtcg atgctgatcg tgatgagttc gaccatgcga
    62881 tcgaggccca tgttcttctc gctcaaatag tgcgtttgct gttcgcagac tttcgtatcg
    62941 agagacggga cgatgctgat gatgcggacc ttgcctttgc ccttggtgtc attgatggga
    63001 atcatcgaga ggtcgatttg cgccaatttc acatcgcgca atttgtcgcc gaccttgatg
    63061 cccataccgg tgagcatcag cggcttgccc tgaaacagga tattgttgcc ttctccggcc
    63121 actgcgcttc cgtcggcgat cggcatgtct ttgtatgaga accccccctt gccagtgccc
    63181 ggcaaggttc cgcacgcgct caggccgaga cacaacaggc ctgcaagaag acgtggaacc
    63241 agaacgccag acaggacagg ggcactcatc gacctcataa gacctctcca tgaaaaaagg
    63301 gacgtacgct ctccattgtc actgtatggc ccgctgggaa gactgtcaag gctgaaggaa
    63361 ctccatgatg tgccggttga ccgcctgtgg ccgctcccat tgaggaatgt ggccggcctc
    63421 gggaatcaca atcaaccgtg agtgcggaat catcgcctgg agatcttggc cgacttgcgg
    63481 agggaagagg cgatcatgct cgccccacag gatcaacgtg gactggcgaa ttgctgtgag
    63541 tcgcggcgca tacagctgct cccacagcgg caggctgtcg cgcaacgaga gtaaggggcc
    63601 gatcatgtct tcccgctggc ggtttcggtt tgatcgctcc agcacgagcg gggtgatgag
    63661 gctgtgatcg tagacaacct ccttgagcac ggcttccatc gtccggcttc cgaacagcga
    63721 tgccccgaac cgggccatcc aggcgggcac gtgcgtgttg atggcccgct gcatgagcgg
    63781 gctcacgagt cgttcccgaa catggtccgg cagggtatcg atcaagacca gacggtcaac
    63841 gcgctccgga tatgtcaggg ccatgccaat ggccacgccg ccgcccatcg aattgccgat
    63901 gacggtggct gtctgcaggc ccagcccatc catgagtcct cgtatggatt caatcagtgc
    63961 ggagggacgg tattcgatgt cgggtttctc ggaaaggccg gagccgagga gatccggcgt
    64021 aatcacacgg aagtgcttgg tcaagggctg ctggtattcc cactgccaca tggatccgcc
    64081 gtagccatgg agcagaatca gtgtcggccc ctcgccttca tcaaggtagg cgatccggtg
    64141 gccggtgacg gaaatggtat gaacaggcaa tcgctggatc gcgtcgaacc agggagggac
    64201 atccggccgt gccgcgcaac cgctcatgag gagactcgca agaaaccagg tggccaggtg
    64261 atggggcgct ggggcaacaa accggacgag agaggccggg cgcggcaccg gctactccaa
    64321 ttgaatgacg gtttcgtcga ttttgacgtt gtctccctca gcaacaagga tggcggcaac
    64381 ccgcccgtcc atgggggccg gaacctggct ttccatcttc atggcctcga tgatcaagag
    64441 aggatcgccc gttttcacct gggcgccatc cgtcaccaac accttcacca cacggcccgg
    64501 catgggcggg gccacatcac cgggtttcgt cggtcgggga cgtttcggct tcgacgtgct
    64561 gctggcctcg ggagattccg gcacgccggc caacacttcc tgcaacggtt caagggagac
    64621 ttcctgcagt cggtcattga cgcggatgta atagggcttg cggccgtcgg tggtgcggcc
    64681 ggagcctgag accacgacat ggtaattctc gccatgcacc gtaatgttga attcggccgg
    64741 agccagatgg aggtcgtgcg ccacggccgg gcctttggtg tcggtcggct cgagcggctc
    64801 cggctgcagg gcgccttgct cgcgtgcctc gaagaaatcc cgggcaatgg ccggaaacag
    64861 ggcaaaggac aactggtctt ccagggtcgt ggcggattcc ggcatgtcct tcttgagttt
    64921 ttcgaattct gcttccaggc ggtccgccgg ccggcctttt accggttctt cgtcgccgat
    64981 cgctcgggcc ataatctctt tatcaagagg gcctggtgca cggccgtaga ggcccaggaa
    65041 gtagttcttg gtttccgtgg tgatgacttt gtagcgctcg ccctgttcgc cggtcagtac
    65101 gttgagtgtg gcttgcgtgc cgacgatttg gctggtaggc gtgacgagcg ggggatagcc
    65161 catgtccttc cggacgcggg ggatttcgtc catcacttcc ttcatccggt cgagggcgtt
    65221 ttgctccgcc agttgcgcag cgaggttgga caacatgcca ccggggattt gggacgttag
    65281 aatttccgca tcgacaccgg tgaagtcgct ttcaaattgc cggtactttc ggcgcaccgt
    65341 ccggaaatgc tctgcgatgg gctggaggtc ttccagatcc aattggctgt cgtagggggt
    65401 gccgcgtaat gccgcgacca tcgattcggt cggcgggtgc gaagcccctc ccgctagcgg
    65461 cgaaatggac gtgtccagaa gatccaagcc cgccatcacg gccatcagag ccgtcatggt
    65521 gcccatgccc gaggtgtaat gggaatggag gtgaatggga acacgaaccg ctgctttcaa
    65581 actcttgacc aaccggtagg catccaccgg cgccagaagt ccggccatat ccttgatgca
    65641 aatcgtgtcg gcgccgaggt cctccaggcg tttccccatc gtgacgaatc cgtccaatcg
    65701 atggacgggg ctcgtcgtat aggaaattgc cgcttctacg tgtttctcgc aggctttgac
    65761 ttcgcggatg gcccgttcca ggttacgcac atcgttgagc gcatcgaata tgcggaacac
    65821 atcgatgcca ttggcggccg atcgttcgat gaatttgtcg agcacgtcgt cggcataatg
    65881 ccggtagccc acgagattct gcccccgcag gagcatctgc agcttggtct tcggcatcgc
    65941 ggcacgcagt gcgcggagcc gctcccacgg atcttctttg agaaaacgca ggcaggtatc
    66001 gaaggttgcg ccgccccaga cttccaaaga ccagaatccc acnnnnnnnn nnnnnnnnnn
    66061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    66121 nnnnnnnnnn nnnnnnnnnn nnggagactt tttcgatacg gctttcttgg tcttttttat
    66181 tgccatactg gcggcctcga ggcggcggaa tcgctcgcgt aacagggttg aggtgctgtg
    66241 tgcctggtgg ctgagaggtc agagtccttc gtaggcggcg attgctgcgg aaatcgccaa
    66301 caccaggtcc tcaggctcct cggattcttc gtattgatac aggtctggat gagtctccag
    66361 gtaggaagta tcgaatcgtc ccgcctggaa atcctgttcc atcatcacgt tcttcatgaa
    66421 cggaatggtc gttttcacgc cacgcaggac gtattcttcg agcgaacgcc gcatgcggct
    66481 gacggcttcc tcccatgtgc gtccacgcac ggtgagtttt gccagtaagg catcgtaata
    66541 gggtggaatc gtatagtccc ggtagaccgc gccgtcgata cgaactccga tgccgcctgg
    66601 ggaaaggtag gcggtgacgg tgccggtgca gggcataaag ttgttacgcg gatcttcggc
    66661 attgatgcgg cattggatcg cgtggccttg cagggtgaca tccttttgcc ggatctccaa
    66721 tggtttgcct gccgcgatgg aaatttgatt gcgcacgatg tcgatcgccg taatctgctc
    66781 cgtgacggta tgttcgactt gcaaccgggg attcatttcc atgaaataga aatggccttc
    66841 gtggtcgagg aggaattcca ccgtgccggc attgtcgtac ttcacggctt tggcgatggc
    66901 gatggcggct tcacccattt gcgcgcgcaa ttttgccgtc agcaccagcg aaggggcgat
    66961 ttcaatcagt ttctggtgcc ggcgctgaat cgaacaatcc cgctcgccga ggtggatgat
    67021 gttgccgtgt ttgtcgccca ggatctgaaa ttcaatatgg tgcggccgct cgatgtactt
    67081 ttcaatgaag atgctgccgt cgccgaaagc cgccagcgct tcccgtgccg cgacttccat
    67141 attttcgcgc agctcctggt cggagcggac tacgcgaagc cctcgtccgc cgccgccggc
    67201 gctggccttg atcatgacgg ggtaattgat ccgatggacg aactctaagg cctcctcgat
    67261 gctggtgacc ccgccttcgg tgccaggaac aatcggaagc cctgcctgct gggcgatctg
    67321 ccgggccttg accttgctgc ccatgaggtc gatcgtttcg ggagaaggcc cgatgaaggt
    67381 gattccagag gcatggcaga ggcgggcgaa cttggcgttt tccgacaaga acccataccc
    67441 gggatggatc gcgtcggcgc cgatacgctt cgcgatttcc acgatctgtt ttccgtccag
    67501 aaacccttta accggaccag gacctacgag ataggactca tcagcttttt tgacgtagat
    67561 acccgaggaa tcagcctcgg aatagatcgc cgctgtcgcg atgttgagct cgcggcagcc
    67621 gcggatgatg cgcatggcga tttcgccacg gttggcaata aggatcttgc ggaacatgct
    67681 gagcctgcgt gaggttcgga gccggagctc acctctgggt cgcctcccaa aaagatcgcg
    67741 taacctagca tagggtcaag agagttgtcg agacgaaggg cggtaaaatg gcgaatccgg
    67801 aagggcacga atcgggcagg aggcacagcg cctcctgcca cggcgggaat tacttggcct
    67861 gaatgagaag tggcttcgac tgcgcgctgc cgccgccggc gacgacaatg atgaatgaca
    67921 tgcccgcctt cgcgtccggc accacggctt caatcgtcga ttcgttcacg aactggtact
    67981 cgatcttgtc tttgggcgcc gcgctgaacg tgactccatg gaaacattcc ttgctgccga
    68041 agttttcgcc tttgatcacg attttatcgc cgggtttagc ttcatctggt tctactttgc
    68101 cgatggaggg gcgctttgag cgatcacaga ccggatcctt ctcaagcttg ttggtatccg
    68161 accccttgat cgattcggta ttgaacatcg tgtagccggc gccttccacc atggcccctt
    68221 cctgggcctg gcctgatgga acggccatac agaggacgcc gagagcaaca acggaaccga
    68281 gggccacggt catgaatgtg cgcatgaaag cctcctatca gggagatgat gtcttcggga
    68341 gcggtgtata agaatcgctg ataattttct gaccctcgtc cgacagggcg aattgttcaa
    68401 acgcggccac gagagggtcg gcatcattat tggagataag gagaatcggc cgccgtaagg
    68461 aataacgtcc gtccttgacc gtgggtgttt ctggttccac tttatcgacg gggagcagac
    68521 gcaccggcac tccggaggcg actgcttcca aggcttggcc cagagacaga taggtgacgg
    68581 cagaattggg cggcaaagtc ccggcgatgg ttttgatgac cttctcgtcc ttcgcgatca
    68641 ctttggtgct gtcgggaatc ttgccggtaa tgcccaggag ttgctcaaag gcgtcacgat
    68701 tattttcgtt gcgcggccga tcgatgagca gcaccttggt atccggtcca cccaggtcgg
    68761 cccagacctt atactttccg gaaaagaggt cggcgacctc ctgtttggtg acttctttcg
    68821 tgaaattgga gcggtggacc atgatggcaa tgccgtccca cgcgatttgg acggagtgca
    68881 gcccgtttgc cgaggcgccg gtgacggcga tgtgcgcctg cttggctttg accatgtcga
    68941 gtggtttgga gttgtcgtcc cagacgacat cgatataggc gcgcgggttg gctttttcga
    69001 acgcgtgcgc cagggattcc atcacgtgtt gctcaggtcc gtgcccggcg atcaccatgg
    69061 agccggcgac ttcggctgag gccggcaacg ttgacagaga gaaaagtccg gcacaaagga
    69121 gggcgctgat acgggaatac atgctgaacg attctccctc tcgcccctga gcggccttcc
    69181 ggtgggcatc gtggcgcggc aggccggggc ggcagtccct tccgctcacg cgacctccgc
    69241 ttaggattcc gggctgtcgg tcggggttac tgcaccggac atcatgtccg gcgttacatc
    69301 cacgcgtttg cccatggcgg gaggaagttt tgagaagcga tccatgcgtt catgaagcat
    69361 gtcgtacgct ttgatttcct caaatccagg cttgtggctc cctttgacct tcgaggcgaa
    69421 ggcggacaag atccgggttg cccccatatg ggtgcactgt ggacacaccg tatcgtccgg
    69481 ccgcgcatgg atggattgcg tggcctcgaa ccgatgggta cattgatcac agcgatattc
    69541 gtaaaccggc attgtcgact ccttacagct ggagaagaat gcacttcatg gctgcccata
    69601 ggagggctag ccgagataaa gcagttctct gtttggaaac gcttgaccct atagataact
    69661 ttgcactatt gtaccgaatc tatgtgccga aacgcgagct acaattgaag gagcggttga
    69721 aatgcccctg ttaatccgga agtacaaagg caatggcggt gttatgcagg aagagcgcat
    69781 cgacgatccg gaccggatcg tacggtatat gcgtctgttc gaagagaagg acgtcaagaa
    69841 gctcgaaacc ggagccaaga cggtgatcga gaaggacgag tggcagctcc tgccctagca
    69901 cgtacctcct gggttcatcc catcatctca tgtgtgtttc cgtcgcgggt cgttgcggct
    69961 tgatatgtcc tgcgcattgc tctctccgag aagtgcgtgg tagggttggg ctgcgacggt
    70021 cctgacgaca gagtccaacg gggtaccatg atctattgga tccacattgc acgcgcgatt
    70081 gatcgagtca cacttcatcg ggaccgttgt tcggaagtgc cctccagcat ttcgagtagt
    70141 gacttctggg agggcggctg gtttgactat cctgacaagg aacgcgcgct cgcagcgatg
    70201 gagcaggccg gtactaccga cgagcgcaag tgcgcgctct gcaaaccctg atcgattcac
    70261 acgagagtgc tgagccgata gatccacgcc ggctcacgtt cacggcagat ccggttcatc
    70321 attcagtacg tccaatcgcc tgaccatgcc tcaacttgcg cttctcctca caacgtttgt
    70381 gtggggcgca acattcccgg ccaccaaagc cgccctcgaa caaatcacgc cgctggcttt
    70441 tctgttcctc cgatttttac tcggcatgct gctggtcttc gcggtgctgc tcctattgcg
    70501 ccggaaactg acgcgcgatg ccgcgatgct gcggatgagt ctcatcgcca gcctctggct
    70561 gttcctcgga tatgtgttgc agacggtggg actgcatttg acgacggcct ccaactcggc
    70621 cttcattacc gtattgtacg tggtgttcgt tccgctgtat ctccgccgct tgagcgcgca
    70681 cacctggatc tccaacggca tagcgttgat tgggctgtgg tttctcgtca agcccacggc
    70741 ctctgccaat cttggtgatc tgctgacgct cggcagcgcc gcggcgtttg cggcacacat
    70801 ggtctgtctc gagcgctaca ccagaacgac cgacgctgtc tcgttgttcg cctggcaact
    70861 ggtgatgatg accgtagcga tgctgggggc gatgtggtgg gaacagccga cggcggccat
    70921 gttcgagccg agccgtgtgt tgctgttggg cctgggagtt accgggatac tggcgaccgg
    70981 cgcgttcgcc gtgcagatgt gggcgcagca gctgctgcct gcacaacagg ttgcattatt
    71041 gtttgccgtg gagccggcta tcgcggcttg gcttgcatgg tatttcctgg gcgaaaatct
    71101 ggatgcgcaa ggatggttcg gcagcgcgat gattctgggc ggtgtgctgc tcggatctcg
    71161 cgtgccaggg gagatgcctc aggtatctcc gacgccggtc gttgtgcggt cagaggggag
    71221 atgatatggc tcaaaagttc ggcaacagcc gttgggtgca agagggattt ctcgataatc
    71281 gacaggacgg gacggtggtc gggcgcatca cgtttgcggt cttgggcgcg atcgattttt
    71341 atctgacggg caattgccgg ggagaaattt ccggcaaggt gatccgattc aaaaatagcc
    71401 ggttcgccga cgaggacctt gccggtcaag tgttagggga tgtcgaaagt ccgcagatcg
    71461 gagatgccag cctcatctcg ttcgatcctc atccccatct ggtgccccat ccatacattg
    71521 aatggttttc gatgcgaaag aatcactatc gcatcgaact cgtgccggag gatgcctgga
    71581 ttgcgacaga ggcagagatc gctgagatcg atgctgcgag tcgtgacatc cgtgatcgct
    71641 tggcgccgca gtatggcagc aaatcacggt cggcggatga atcggagtgg gtgtaacgcg
    71701 gagtgtcggg ggcgggcagt gaattggccg cccccgctgt gactcaggcg agtttgttct
    71761 tgccttctcg aacgtgggcc ggcacctcgc gaatatccca taccagacct acagcctgca
    71821 tggcgcgcag catgtagtag gtgatgtcga tttcccacca gtagaacccc tgccgggttg
    71881 acgcggcata gtagtggtga ttgttgtgcc acccttcgcc gagcgtgatc atggcgagaa
    71941 tgaaattgtt tttgctgtcg tcacccgtct tatagcgctg tgatccatac acgtgggaaa
    72001 gggagttgat cgtacaggtg ccatggagca gtgcgacggt ggagacgaag aacccccaga
    72061 tcagcatttg cggaccattg gtgccgagtc ccggcgcata ggactccagc aatttcccca
    72121 atccgaacat gccgaatccg cagatcgtcg gcaccagggt atcgaagcga tccaggaacc
    72181 gcagttcagg aaacttggca aagtcgccga tgctcttcag tcggggcgga aagaatttct
    72241 tcgagctgat ccaaccgatg tgggcccaga gaaatcctcc ctggcgcacc gaatgcgtat
    72301 cctcaggttt gtccgaatag atgtgatggt ggcgatgatg gccggcccac cagaggggac
    72361 cccgttgagc gcatgacgat cccagcaacg caaaggcgaa ttggcacgcg cgagacgttt
    72421 taaatgtccg atgggagaag taccggtggt accacccggt gatggcgaac atgcggatga
    72481 agtaaaaggc ggcgcagacg ccgagcgcaa cccagctcca gccgacgata aacaccccga
    72541 ggcagatcaa gtgaacggtg atgaggggga tggcccgcag ccagtcgaca gtggcgggag
    72601 ccgcatcagt tttcatgttt tcgatgccgg cccaggagtc aaaccaatgc aggatagtga
    72661 gccagggcgt tgggctcgtg gcctgttctg caggctgttc ggcagttttg gacagctcac
    72721 cgttgtcggg taaggtgagc ggatgcagat cactactcat gccacctcca cagttgtgcg
    72781 aataggatgc ggtaccgagg ggtcgcgccg ccgttgcact agcgtgacgt aatcgttgcg
    72841 gcgcttgcga ttgatgcgat ggggcaggcc gctgaatgtt tcggatggtg tcgatcggtg
    72901 agcgtataga ctcagccctc aagacacgtg catccattat acacaggttc gtaggaaaat
    72961 gtcgtgagtt ttttcgcctt tcacgacgaa cctttttccc cacactgctg ccctgacccg
    73021 agccgtaggt acaggccggg gagcgggatg agcgtgccac gaatggctca agtcggtgca
    73081 ctgcgcaaga ttgtttgact ctgttcggac cggccctcta aaatgcgccc cattatgaat
    73141 gatcgatttc tcaaagcgtg ccggcgcgaa ccggttgatt gtacgccggt ctggttcatg
    73201 cgccaggcgg gccgctatat gatcgaatac cgtcgattgc gggaaaaaca ctcgattctt
    73261 gacctgtgca aaacgccgga attggcagct caggtcaccc tgcagcccat tgaccggttt
    73321 gcgctcgatg cagccattat ttttgccgac attctgctgc cgctggaacc gatgggactg
    73381 tcgctggagt tcgcggaggg ggaagggccg attatccata atccccttcg ggatcgggcg
    73441 gcggtggagc ggctcaagat gctcgatgac agcgacctcc aatatgtcat ggatgccatc
    73501 agcctgacgc gcaagatgtt ggccggtcga gtgccgctga tcggctttgc cggagcgccg
    73561 tttactttgg ccagttatgc gatcgaaggc ggcagttcac ggaactatat ccacaccaag
    73621 cagatgatgt atggcgagcc ggaagtctgg caccgcctga tggataagtt cgcgcgagcg
    73681 atcaccgggt atttgcgtcg gcagatcaag gccggcgccc aggccgtgca gctcttcgac
    73741 agttgggtgg gctgcctgtc ggcgggagac tatgccgaat atgtgatgcc gcatgtgcaa
    73801 ttgatttttg acggcctcaa gcacgaaggt gtgccgctga ttcatttcgg gacgggtacg
    73861 acggccattc tcaaatcgat gcgccaggcc ggtggtgacg tgatcggcgt cgattggcgt
    73921 atcccgatcg acgaggcctg ggccatggtg ggatacgatc gcgccgtgca gggaaacctc
    73981 gatccggtca ccttgtttgg gccgatgcac gaaatcgagc gtcgcgtgac ggatattctt
    74041 cggcgggccg gagggcgacc cgggcacatt ttcaatctcg ggcatgggat cctccccaat
    74101 actcccgtgg agcatgtggc cgccacgatc gatctggtcc ataagttgag cgcccgctga
    74161 atctggtgag acgtaggcgc tcattgcccg gcaggcgctt gattcgcgag agacgtcttc
    74221 ctggtcacgg ctgacgaggt ctcggatgtc ggcagcacca cgcccgattg ccctgttgct
    74281 gatggccatg ggcgggcccg atagtctgga gaatgtagag ccgtaccttc tggatgtccg
    74341 cggcgggcgt ccgacccctc cggagttggt ggaggaaatc cggacgcggt accgtgtgac
    74401 gggtgggaag tctcctgtac tcgacataac gtgcgaggtg gccgccgcct tggaacagcg
    74461 actgaacgca tccggcgaaa ggcgctttcg gtgctacgtg ggattgcggc actggcatcc
    74521 gttcatcagg gacacctacg ctgaactgct caaggcggat cctgatcata tcgtgggctt
    74581 gtgcatggcg cctcagtact cgtcgctcag cattggcgcc tatgtgaaga aggtcgaaga
    74641 ggcgcgtgcg gaactggcgg atgagacgcc gatcagcttc gtgaagagct ggcaccgtca
    74701 tccgttgtta atcgccgcga tcgtcgcgca tatccgccat acgctggagc gatttcccgt
    74761 ggaggtccgc gcgcaagtgt ccgtgctctt tacggcccat agtctgccgg agcgggtggt
    74821 ggccatgaag gattcctacc cggaggaagt cggcgctacc gtccaagccg tatgtgcgca
    74881 actcggcgga caaccgacgc ggttcgccta tcaaagtcag gggcgctccg gcgagaagtg
    74941 gctcgggcct tctgtcgagg agacgctgga agacttggcg caagccggtc atcaccatgt
    75001 gcttgtggcg cccatcggtt ttctttgcga ccatgtggaa acgctgtacg acatcgatat
    75061 cgagctcacg cagttggccc gtacgaaggg gatccaactg gaacgaatac ccatgttgaa
    75121 cgcctcggcc cccctgatcg acattctgac gtcggtcgtg gagacgcacg agtcctcgct
    75181 cgttcattag cggcaccacc tgtggcgcgc acttcacggt cagtggtcat tatcggtgga
    75241 ggcatctcag gcctctccac ggcctttgct ctcctggagc aagccgcagc ggccgatgtg
    75301 ccgctgtcct gcaccatcct cgatgccgcg cctgtctggg gcggaaagat cgtcacccat
    75361 cgtgtcggcc ggttggttat ggaggcaggt ccggattcct tcctgtctca gaagccctgg
    75421 gcaatggacc tctgtcggcg gctcgaaatc gccgatgagc ttatcaatac gaaccctgtt
    75481 gaaaaaaagg ccagcgtatt gagaggcggg cagttgcacg agttgcccga agggctcgtg
    75541 acctttacgc cgactcaatt aggtccgttt tttcgcagcg gattgctgtc gtgggtcgac
    75601 ctggcccgta tgggttgtga tgtgctgatt cccccgcgcc ggtccacgga ggatgaatcg
    75661 ctggcttcct ttttccgccg ccgattcgga cagcatgcct gcgagcgggt catggaaccg
    75721 ctgatggcgg gaatctacgc gggtgatgcc gagcagatga gcctgcgcgc gacgtttccc
    75781 cggttttatg agcttgagca gacacatggc agtgtgattc ggggcatgat ggcggctcgt
    75841 cgagccaggg cgcaaaaggc ctccgatggg cgtcctcggc ataccatgtt tgtcacgctg
    75901 aaaaacggcc tcgcggatct cgtcgccgga ctgaccacgc gtatccggga gactggcggc
    75961 gtcttgaagt cgggtgtgca agcggaagcg cttcgggtac gctcgcacca ggcgggacgc
    76021 tggatgtacg atgtgatctg caccgatggg acggcgctgt ccgcggaagc gttagtgctc
    76081 gcgacaccgg cctatgtgag cgccgacctg gttcggccgc tgagcccgct ggcggctgga
    76141 ttgatggaga cgattcccta cgcttcgacg gccaccattt ccttgatcta ccccgccgct
    76201 gcggtgggaa cccgcttgca aggctttggt ttcgtggttc ctcgggttga gggccgtgac
    76261 ctgattgccg cgacctggac gtccatcaag tggccgcacc gagcgcctcc cgaagaggtg
    76321 tccgtgcgct gctatctcgg tggggtggga cgcgaggcca tcctgcagca ggacgatgag
    76381 gcattggtcc gttgcgtgcg cgaagaattg gcgtctatcg tcggtctgca ggcgacaccg
    76441 cattatgtcg aggtcaaccg gtggcatcgg gcgatgccgc aatatacgct cgggcatctc
    76501 gatcgactga cacagctcga tgctgcgctt tcacgtttcg gcggattggc cgtcaccggc
    76561 gcgggatatc gcggcgtcgg tttgcccgat tgcatcagag acggcgcaga agcggcggca
    76621 cagacgttac gctacctcca aacagcctcc aaacgagagg cggaatcgtg agagacgaag
    76681 caacagaagg acatggacga tgttaaatga ccagttggtg atctccagtg tagctgggcc
    76741 gtttcgcgaa ccccgggagc cggtgttttc gtatgactat tccatccaac gggcgacctg
    76801 ggcggccact catgcggttc gcgtgaagat cgcgctggca gaagagctgg actatgtgaa
    76861 aacgaagctc ctgggaaccg tgaccggcag cccgggccag cagttgatgc tgaataagct
    76921 gctgtcgcgc aagatcggcg accaaaagct ccgcatcgcc gaggaggaag ggtggttgaa
    76981 ggagcgcgcc gatgtcctgg tgcctccctt cac
//
LOCUS       DAOQPD010000008        75075 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_111_length_75075_cov_21.896868, whole genome shotgun sequence.
ACCESSION   DAOQPD010000008 DAOQPD010000000
VERSION     DAOQPD010000008.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 75075)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 75075)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75075
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_111_length_75075_cov_21.896868"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..4468)
                     /locus_tag="PK063_03455"
     CDS             complement(<1..4468)
                     /locus_tag="PK063_03455"
                     /inference="COORDINATES: protein motif:HMM:NF024583.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HMZ96127.1"
                     /translation="MNTKLRSRSGKRQQSGVLYEEGHDKAVLNILQAVKKGDFSVRLP
                     AEWDGMAGKIADEINGLIELNAMFSEELKRVSHAVGKKGKLSERASVPEARGEWKTNI
                     EAVNGLIDDLVRPTTEMARVIGAVAKGDLTQSVALEAEGHPLRGEFLSTAKTVNSMVG
                     QLDAFAAEVTRVAREVGTEGKLGGQAVVPGVAGTWKDLTDNVNSMASNLTNQVRNIAE
                     VTIAVANGDLSKKITADVRGEILQLKDTINTMVDQLRSFAAEVTRVAREVGTDGKLGG
                     QAVVPGVAGTWKDLTDSVNSMASNLTNQVRNIADVTVAVANGDLSKKITVDVRGEILQ
                     LKDTINTMVDQLRSFAAEVTRVAREVGTDGKLGGQAQVRDVSGVWKDLTESVNLMAGN
                     LTAQVRNIADVTTAVANGDLSKKITADVRGEILQLKEAINTMVDQLRGFAAEVTRVAR
                     EVGTEGKLGGQAVVPGVAGTWKDLTDSVNSMASNLTNQVRNIAEVTTAVANGDLSKKI
                     TADVRGEILQLKDTINTMVDQLRSFAAEVTRVAREVGTDGKLGGQAQVRDVSGVWKDL
                     TDSVNSMASNLTAQVRNIAEVTTAVANGDLSKKITADVRGEILQLKEAINTMVDQLRS
                     FAAEVTRVALEVGTEGKLGGQAQVRDVSGVWKDLTESVNLMAGNLTDQVRNIAEVTIA
                     VANGDLSKKITVDVRGEILQLKEAINTMVDQLRSFAAEVTRVAREVGTEGKLGGQAAV
                     SGVAGTWKDLTDSVNSMASNLTDQVRNIAYVTIAVANGDLSKKITADVRGEILQLKEA
                     INTMVDQLRSFAAEVTRVAREVGTEGKLGGQAQVRDVSGVWKDLTDSVNLMAGNLTDQ
                     VRNIANVTIAVANGDLSKKITVDVHGEILQLKEAINTMVDQLRSFAAEVTRVAREVGT
                     DGKLGGQAIVPGVAGTWKDLTDSVNSMARNLTAQVRNIAEVTIAVASGDLSKKITVDV
                     RGEILQLKDTTNTMVDQLNAFAAEVTRVAREVGTEGKLGGQAVVPGVAGTWKDLTDSV
                     NAMASNLTAQVRNIAEVTIAVASGDLSKKITVDVRGEILQLKDTTNTMVDQLNAFAAE
                     VTRVAREVGTEGKLGGQAVVPGVAGTWKDLTDSVNAMASNLTVQLRDMSNVATSIANG
                     DLTRQITVDVRGEILQIKDVINRMVAQLSAFASEVTRVAREVGTEGKLGGQAIVPGVP
                     GTWKDLTESVNLLAANLTTQVRAIAEVATAVTQGDLTRSIQVQARGEVAELKDNINVM
                     IRTLRATTDQNTEQDWLKTNLAKFTRMMQGQRDLTTVGDLLLSELAPLVNAQYGAIYQ
                     RDTADKPLLRLLASYAGADETVVSDDMRIGGGLVAQCAREKRRIVLTDVPSDYIRIRS
                     GLGQARARNVIVLPVLFEGQTKAVIELATLSEFTPTHVAFLGQLTETIGVVVNTIEAT
                     MQTEGLLQQSQNLATELQAQQKELQQTNEELAKKAQQLAEQNAEVERKNREIE"
     gene            complement(4756..5142)
                     /locus_tag="PK063_03460"
     CDS             complement(4756..5142)
                     /locus_tag="PK063_03460"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96128.1"
                     /translation="MINELNRPIQEPNVGRAVLGTSLGQSASYCGATAILSLHQPVIE
                     VSESDGNFNVYADFRPVLENTSMQVAVEFAQQGIILTGGTVERYLPIPTDAYIGHARV
                     TVTGGIARISIPTADAGHRWRSIVMW"
     gene            5350..7326
                     /locus_tag="PK063_03465"
     CDS             5350..7326
                     /locus_tag="PK063_03465"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ96129.1"
                     /translation="MPSPDETSPSIPQPGFPLDFMLAHLAAIVECSDDAIISKDLNGM
                     ITSWNRGAQHLFGYTACEMIGQPVLRLIPEDRQAEEPRILERLRRGERIDHYETVRKR
                     KDGTLIEISLSVSPIKDREGRIIGASKIARAISELKQGERNLAHLVEALPAAVYTTDA
                     DGRITRYNQAAVDLWGQRPSLETARWSGSWRQYWADGRPMPPEECPLAQSLALNRPVS
                     GLETIVERPDGTRLPVASHPTPLRDASGAPIGGVDILVDLTEQKRAERDMQNSAAELE
                     RRIVERTGELLLSQERLRALASDLTLTEQRERRHLATELHDYLAQLVVASRIRLAQVI
                     PTIHDATASAALTKIDGMLDQALTYTRSLVAELSPHILYQFGLSQSLVWLGEQMKQHG
                     LEVAVKTMAPSFTLPDDQAVLLFQSVRELLFNVIKHAKVDRAAITINVDEDRRELWIC
                     VEDEGAGFDVTDLSVAKNTRCKFGLLSIRERMELLGGECEVSSVPGSGTVAILRLPLA
                     SGALKQPFPLAADTAQTITPSIDASSRNINILLVDDHAMVRQGLRSILDAHDNLTVVG
                     EGADGQDAVVMARSLRPDVVIMDVNLPIIDGIEATRILTQEHPSIMVIGISVRNDPQV
                     HDAMTEAGAVAFLPKESAADQLYEVILRAFPVQA"
     gene            7534..11079
                     /locus_tag="PK063_03470"
     CDS             7534..11079
                     /locus_tag="PK063_03470"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ96130.1"
                     /translation="MTSVLLTLQRLVPSAAGLAIGFPVFAFLCWAYNPTFLYNLSPSA
                     GTVKPSTMAAICFCGLSLWLQADEAAMTRARRRMAQGFAGLAGLLAAVTMLEYLLSLD
                     LGVDLWLASVPDLAVDSHPGRMAPATAFALFMLGLALIQLDSKHSGQDQASHYLALAG
                     GTIGAIALVGYLYGVQTLYKVGTSNTISIFSAALLLALGLGILSARPTRGFMATLTSD
                     ELGAVMLRRVLPFAIALPILAGWIRIAAQRSGRYDFNFGVALAVSAVMLIILAFLWLL
                     AGNLNRSDGQKKHILQILQQREARHRLALKAGRMGTFHQDLDRHTLVFSPELEHIFGL
                     PAMSFGSTFAAFQDLVHPEDRAHVLKTINYAIQHRSAYDLECRILRQDPPEEAWIAVT
                     GQVLPDSTGHPRQITGVMFDITERKHSVTALQQSEQQLRVITDALPGLIASVDCDERY
                     RFVNAGYEHQFGLSRDQIVGLSVKDLLKEDYSTVQPFIRRVLSGERISFETTLLDERG
                     EQTLLSTYVPDRNSEGMVAGFYALITNITERKRTESALRESEERFRHLFEQASDGIVT
                     ADMNGQYLDVNNRACQMLGYTREELFDLRVPDLLDPHDYPRLRAIKAELIQGHRHSGE
                     WKLRRKDGGTISVEISARLQPDRRWHAIVRDITERKRADAGLRESEAYFRMLADATPV
                     LVWKAGTDRLCSWLNRSWLEYTGRLLDDELGTGRTDSIHPDDRDEFNRVYNQHFSRQE
                     PFELEYRLRRQDGTYGWILDRGVPLLSAAGVFSGYLGAALDITDRKLAEEQLQQWTVE
                     LEKRVDERTQALVHSQARLRALVSDLSATEEQERRRLATELHDYLAQLLVVGRMKLSQ
                     ARPQVRNPKTEQLLSEADDMLTQSLNYTRSLVAELSPQILYQFGLPAALKWLAGQMKS
                     HGLSVSIQCGIDQLTLAEERAVILYQSVRELLFNVAKHAGTGEAMITLDQSPTNQVLI
                     TVADNGRGFNPAILVDTEGHHPGRFGLFNVQERIEAIGGTLSLKSSEGCGTTVTLIVP
                     LKPFPESAVESDLPVDGHVPDVLRTPSQRLRILLVDDHAMVRQGLRSVLESYTDLEVV
                     GEAGDGGTAISIASALKPDVVVMDINMPNIDGIEATRHILSEHPDVVVIGLSVQNERH
                     IEEAMLKAGAAVFVTKERAAGQLYEAIVSTVRTRR"
     gene            complement(11094..11261)
                     /locus_tag="PK063_03475"
     CDS             complement(11094..11261)
                     /locus_tag="PK063_03475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013538518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1328 domain-containing protein"
                     /protein_id="HMZ96131.1"
                     /translation="MLSWAVTFLVIGLIAGVLGVTGVAGTATHIAYVLFVIFLILAVI
                     GMVMGRRPPAV"
     gene            complement(11548..12612)
                     /locus_tag="PK063_03480"
     CDS             complement(11548..12612)
                     /locus_tag="PK063_03480"
                     /inference="COORDINATES: protein motif:HMM:NF018439.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1207 domain-containing protein"
                     /protein_id="HMZ96132.1"
                     /translation="MALFLLGVMAGFAGMAMAASDEYIAGYAAGLLEHEFHLSGAVVQ
                     VEQGRVAVYAKRLAAEDPAKIVTALKAIPGVVSAEVHTGSAPEGAAGPGVVRATTPTA
                     ESKFLPRGLLVDPFHADLRWPHFGASYHSLSSGGREFASAFGESFSVYRDAAPFQGEW
                     ELGIQAGVFGVFDTEKRSIDLINADYTFGIVASYRADRFSGFIRIRHQSSHLGDEFLL
                     NNPQVVRINLSYEEIDLKMSYDLTTWLRVYGGVGTIVRKDPSTLGRETTQGGVELKSP
                     WLFFGGKVRPVAYADFQTHARTHWTTGQSIMAGLQFENARIGDRKLQVLGEYYSGPSP
                     DGQLFTQRVEWIGMGIHLWF"
     gene            complement(12700..13299)
                     /locus_tag="PK063_03485"
     CDS             complement(12700..13299)
                     /locus_tag="PK063_03485"
                     /inference="COORDINATES: protein motif:HMM:NF024895.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HMZ96133.1"
                     /translation="MRQGVLSAALVLCASFLIAGGVVVPSPARAADDKGLFEQMDIGL
                     LSIGGRATYIDPKDGSSRWFGGGQVRLHPWRYLAFEGSADYRRNDIGDTRVHTYPVQV
                     SALIYPLGTTRLAPFLLGGGGWYYTTVKGPGGFDDTQNRFGAHAGGGLQFFFNKHVSI
                     DSTYRYIWLEKIESRDQNIVDKKFQDNGHMVTVGVNFHF"
     gene            complement(13344..13685)
                     /locus_tag="PK063_03490"
     CDS             complement(13344..13685)
                     /locus_tag="PK063_03490"
                     /inference="COORDINATES: protein motif:HMM:NF017353.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HMZ96134.1"
                     /translation="MRLGHWRLSIVALAGILMMTAAGHAGEQHRLRGTQGTLILAVNQ
                     DQLAGMWKQFMGELKQKWAEFTDDDLMLIEGRIDTLEGKIQERYGDRREEVKRWVDEW
                     FESHGEKRTQS"
     gene            complement(13754..14032)
                     /locus_tag="PK063_03495"
     CDS             complement(13754..14032)
                     /locus_tag="PK063_03495"
                     /inference="COORDINATES: protein motif:HMM:NF015378.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HMZ96135.1"
                     /translation="MKKMIAIALLSGVIASPAWALFETNKQLAATATVTLEDAVKHAL
                     KLVPGKAVEAEIGKQDGRTVYEVEIIDSNNKEQKVYVDAQSGQAKIDR"
     gene            complement(14086..14331)
                     /locus_tag="PK063_03500"
     CDS             complement(14086..14331)
                     /locus_tag="PK063_03500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HMZ96136.1"
                     /translation="MNTDQFKGKWVQFKGEVKKQWGKLTDDDLKQVEGDYDKFLGRIQ
                     ERYGDKKEEVMRWADDWYSRQGQAQQGTQHRETQPPR"
     gene            complement(14986..15246)
                     /locus_tag="PK063_03505"
     CDS             complement(14986..15246)
                     /locus_tag="PK063_03505"
                     /inference="COORDINATES: protein motif:HMM:NF014919.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96137.1"
                     /translation="MKVWPGRPYPLGATWDGEGVNFALFSENTTSVELCLFDGPDATR
                     ESHRIRLEERTNQTWHVYLPEGRPGLHYGHCVAACRWQRNCG"
     gene            complement(15304..15843)
                     /locus_tag="PK063_03510"
     CDS             complement(15304..15843)
                     /locus_tag="PK063_03510"
                     /inference="COORDINATES: protein motif:HMM:NF012436.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HMZ96138.1"
                     /translation="MKTEKPQASMIKDVQSIRERARQHIEEGALTADYKADRDTVIKL
                     LNEALATEIVCVLRYRRHYFMAQGMNAESVKAEFLAHAGEEQAHADELAERIVQLGGE
                     PNLSPDGLSSRSHSEYVEGEDLEEMIKEDLIAERIAIESYRDMIAFVGSDDPTTRRLL
                     ETILMKEEEHAEDLVSLLK"
     gene            complement(15883..16074)
                     /locus_tag="PK063_03515"
     CDS             complement(15883..16074)
                     /locus_tag="PK063_03515"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96139.1"
                     /translation="MMPVSLSGNQFGKYMGLLISIAACALVVGTQARTVTQRTDEQGL
                     MTELGLESAWPHVRTDFSR"
     gene            complement(16193..16681)
                     /locus_tag="PK063_03520"
     CDS             complement(16193..16681)
                     /locus_tag="PK063_03520"
                     /inference="COORDINATES: protein motif:HMM:NF012780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HMZ96140.1"
                     /translation="MTSTSSKSNVPRTIAEAGFTRPRRRLYLETRIDEDLGVLPGEVR
                     KVRHVMSSALTVVSPDTSHEEAVSLMAAMNVPVIVVYEGTRLVGMVTDRDVALHRSSR
                     PPTTALTVRDIMSEQVPYCQEDDLLTDAQALMRLSEVDWMPVLDRQGRLAGVLSIYVP
                     PS"
     gene            complement(16711..17007)
                     /locus_tag="PK063_03525"
     CDS             complement(16711..17007)
                     /locus_tag="PK063_03525"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96141.1"
                     /translation="MESSEKAASIRQWINPEERVTVDFENEHDLNAEVIECDGQTVTL
                     LLETAFPHYKQHLTLPLSMISVGEDKSHYTRDPDKPVQYGRLRITVHEARPQAV"
     gene            complement(17307..17942)
                     /locus_tag="PK063_03530"
     CDS             complement(17307..17942)
                     /locus_tag="PK063_03530"
                     /inference="COORDINATES: protein motif:HMM:NF014796.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006801 - superoxide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-Mn family superoxide dismutase"
                     /protein_id="HMZ96142.1"
                     /translation="MAVTQPYQAKAFDLFGLSGISDETLRVHFALYEGYVKAANELRE
                     QLSEFIQQGHVDHEQMPAYSELTRRLGFEFNGMVLHEYYFGNLRRGGGAEPPNGSAFH
                     RAVERTFGSYERWKADFCSVGMMRGVGWAICNVDPARGLVSNHWVSLHEHGNVAGFLP
                     ILVMDVWEHAFLLDYQPSERKQYIDSFFSNIGWGVVEDRLQAGLSSVAIPH"
     gene            18237..18893
                     /locus_tag="PK063_03535"
     CDS             18237..18893
                     /locus_tag="PK063_03535"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ96143.1"
                     /translation="MARARIVIADDHSLVLEAYRQLLEPDFDVVGTASNGQELLNIAP
                     ALNPDIILLDISMPTMNGLEVTKQLRAAIPHAKIIFVTMMSEPFYISQAFQMGASAYV
                     LKQSASTELLSALNAALKNQRYISPQLSLEVQDAIETPWVKPEGFSSKLTPRQQEVLQ
                     LLTKGMSTKEIATTMHVSTKAVEFHKGNITRRLGIRTTAELTRFALSQGLTKLSDQHP
                     "
     gene            complement(18903..19586)
                     /locus_tag="PK063_03540"
     CDS             complement(18903..19586)
                     /locus_tag="PK063_03540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ96144.1"
                     /translation="MKPRVLIADDHTLVAEGVEKLLEHDFQLCGRAADGRALVRAVEK
                     EKPDIALVDIALPLLNGLDACRQIKKSVPEVKLLVLTMHSEQYFVTEAFRAGVSGYVL
                     KQSVADELVFAIKEVLKGRLYVSPSVAENLVAQALHPVAPAPAGAPPSNDSLSGRQRE
                     VLQLIAEGQSTKEIASTLNVSIKTVEFHKTRIMKQLGIHSTAELTKHAIAIGLIAMPQ
                     QPTVPGSQP"
     gene            complement(19675..20967)
                     /locus_tag="PK063_03545"
     CDS             complement(19675..20967)
                     /locus_tag="PK063_03545"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96145.1"
                     /translation="MSCSIVCLFSVGAIGDDLFGLGQDFALAEEPTPIAGEPFRTTLF
                     GEEIYVPPRDRRSVTAISFGIQAIPNGPTQQEVLPFGALYVWRNWDDDNRRLRGTFSG
                     VVNDVDYTIGLRDYPNWSLLFTWDNFILPFGRSEYVQGQRQRGTELEWSYAFAGAGLG
                     YRLPVHPFRQDSAVNISLTYEAGYRWFKGTGHTSADYGVPKDTYEGRIHFRIRADALK
                     RNLMELPHEGFTLGGDVVHGHRAKWDQWGGAPFNTQDFKKEQTYIQASAYALLATGLP
                     FIESDKHRLLSSIHAGIGKDLDRFSAFRLPGRPTGYEWEAISLPMIHGVAFNELFPTR
                     YAVANLQYRYEALFFLYPYVEATWGLVERPVFTSNTAVKSITDSMPALGGGLVTGAPW
                     KSQVELNYTYNFGIYRDPGGAPPTKGGHGIIFFWSKEL"
     gene            21248..22111
                     /locus_tag="PK063_03550"
     CDS             21248..22111
                     /locus_tag="PK063_03550"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96146.1"
                     /translation="MERTYRTQPHCFNGTSAHVPRWRCCLAAAGLFLLTSTTLFANPI
                     EVIYPEGVSEGFVTLKTLDGKKLADGELSQVTTGADRLASRLTFRFADGSLYDETVTF
                     SQKKHLTMLSYQLTQRGPAFPEPLVISLNGETGQYQVRQREKTPDEKLITGRLDLPKD
                     VYNGLTITVLKNLRGQTGAIVHMLVFNPEPKLYEVELARVDEEDTRNTTRKETKATAV
                     HYSLKPRLGWFTAALARLLGRTPPDYHFWLIKKDAPAFVRFEGSLYAGGPSWRIEQVS
                     PRVKQARVPEP"
     gene            complement(22119..22823)
                     /locus_tag="PK063_03555"
     CDS             complement(22119..22823)
                     /locus_tag="PK063_03555"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96147.1"
                     /translation="MRQSNGRAIVMIGIMLGGIVCGEAGPFLVWSAEPVLSVAAAQHD
                     QVHGALAAEGTVDRFILDPRGEVEGLFLADGTHLYVTSRAADQLVRAFAPGNAVRVYG
                     RLMPDERLVQADAVINVTTGTTFTVPLRLDLPMQEQEHTLSMTEMSAAGTIRAFFYHP
                     LKHTIQGMLLSDETQVRFPPDASPALRRSFHVGEHVRVRGNGTINRFGRAVEALAIGR
                     NSAALVPLDASLQRLP"
     gene            complement(22851..24647)
                     /locus_tag="PK063_03560"
     CDS             complement(22851..24647)
                     /locus_tag="PK063_03560"
                     /inference="COORDINATES: protein motif:HMM:NF012926.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 15 protein"
                     /protein_id="HMZ96148.1"
                     /translation="MNATAKIEDYALIGDTHTAALITRQGSLDWLCLPRFDSPACFAA
                     LLGTPEHGRWLITPHEDNTTIRRRYRGDTLVLETLFETPTGTAMLIDFMPPRDRDINV
                     VRVVVGVKGTVRMKMDLTLRFDYGSIVPWVSHQRRFLKAVAGPDAVYLETELELQGVG
                     FSTVADFTVTEGQEIPFTLTWRASHDSPPRPLITERALSQTELWWKKWSQRCTYQGSW
                     RNHVVRSLITLKALTYAPTGGIVAAPTTSLPELLGGVRNWDYRYCWIRDATFTLYALL
                     SAGYHSEAKAWREWLLRAVAGKPSDLQIMYGIRGERRLTELELNWLPGYEQSAPVRIG
                     NAASQQFQLDVYGEMMDTLHQARELGLAASEDAWRVQHAIMEFLETAWDRPDEGIWEV
                     RGPRRHFTHSKVMAWVAVDRAVKAIERCHVDGPLERWRALRETIHEQVCREGYDSNRG
                     TFVQYYGGTSLDGSLLMIPLVGFLPAFDPRVQGTLHAIERELTVDGLVMRYQPTGKLD
                     GLPGEEGMFLPCSFWLVDNLLLSGRVEEARRLYERLIGLSNDLGLLSEEYDLKNKRLV
                     GNFPQAFSHVSLIDSAYGFSRMESPAERRQRS"
     gene            24747..25073
                     /locus_tag="PK063_03565"
     CDS             24747..25073
                     /locus_tag="PK063_03565"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96149.1"
                     /translation="MRKVLAKKTQPRKKTSSAKKRTVKRDIEPAAHVIERKTKKKPAT
                     SAKAKKTTLTKKKTSKTTRKRSPGSSRNAKSVGRAVGKVIGRAIGTVERALTLVRPNS
                     NTPKKQ"
     gene            25195..25518
                     /locus_tag="PK063_03570"
     CDS             25195..25518
                     /locus_tag="PK063_03570"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96150.1"
                     /translation="MAFQVVSKLVSTTLFVALALPAALAAANPAPESGQPQPPSPQQT
                     PPTAPPSRIDPGIQKAPDTVPNPKSIVPPPVVDPKMAIDPERPGGPAHPKPPSPADKP
                     PMPPR"
     gene            complement(25576..26847)
                     /locus_tag="PK063_03575"
     CDS             complement(25576..26847)
                     /locus_tag="PK063_03575"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: protein motif:HMM:NF019604.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HMZ96151.1"
                     /translation="MNQQSRNPVVIVGGGFGGLAAARALHHLKGEVILIDRMNHHVFQ
                     PLLYQVATAALSPADIAWPLRTLLRAQQNVRIMMDEVRAVDRSARRIELRNSEPVSYS
                     SLILSPGARHSYFGHNTWEQDAPGLKTLPDALEIRERMLMAFEKAERLKGTPEARDEL
                     TFVIVGGGPTGVELAGALAEIGRKAMTPDFPVLHQAASRILLIEGGPRILEAFPPALS
                     SRAQASLESLGVTVLLNCRVHDVTSKGVMAGSEFISSAHVIWAAGNVASPILASLDVP
                     LDSSGRVIVGPDLSLKEDPWVFVIGDAAHCLSARQKPLPGLAAVAMQEGRYVAGIIAR
                     CIPDGQRSAFRYRDRGILATIGRAKAVAQFGPISLSGVVAWLAWCFVHIFFLIGFRNR
                     ARVMFEWIWYYVTFKPGARLIYWKDRRINPQ"
     gene            27105..28193
                     /locus_tag="PK063_03580"
     CDS             27105..28193
                     /locus_tag="PK063_03580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HMZ96152.1"
                     /translation="MKIAQVAPLWESVPPVLYGGTERIVSFITEELVRQGHEVTLFAS
                     GDSTTRARLMPMCGEALRPSKVVMNYEAPLTAMIEKVFGSAPEYDLIHSHLEFIPFPL
                     AKRCRTPMLTTLHARLDQPELIPVFRKFADLPLVSVSEAQREPLPWANWQATIHPGIP
                     HSLYTPQYNQGQYLVFLGRVAPEKGLDRAIEIAKRVEMPIRIGAKIDAQHAEYYKSVI
                     EPLLDHPLVEFVGEVTDLEKDDLLGDAYALLAPYAWPEPFGLAIIEALACGTPVIGSR
                     RGAIPEIIEHGVTGFVCDTLDEMTQAIRHVSLLERTRCRQAFETRFTAERMAQEYVTV
                     YGQILGLPDKAPQPSSDLASGLPAAGQI"
     gene            complement(28266..28979)
                     /locus_tag="PK063_03585"
     CDS             complement(28266..28979)
                     /locus_tag="PK063_03585"
                     /inference="COORDINATES: protein motif:HMM:NF017088.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042314 - bacteriochlorophyll binding
                     [Evidence IEA];
                     GO_process: GO:0019684 - photosynthesis, light reaction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRC-barrel domain-containing protein"
                     /protein_id="HMZ96153.1"
                     /translation="MNRRMAMYAGTIALALMTGTPAFSQVSTGSGAPPPDSTMGKGAG
                     TSTPKESPSFDKKTDLTGGKQGVPEEYADTPVRQGKLVEMKDSKYLNASVYGTNGEEI
                     GKIQQVMKDEKTGDIEYVVFVSNESKRPQPIRWSQFKTKGDKLQLTLKKEEIQNALPM
                     SSSKDKSPDLQEYKDKMGQVREAPTVPGSAGVPGQKGPDATGSMGEESVGGGGPSGTS
                     GLPSGKAPGFEGGNPSSKR"
     gene            complement(29033..29395)
                     /locus_tag="PK063_03590"
     CDS             complement(29033..29395)
                     /locus_tag="PK063_03590"
                     /inference="COORDINATES: protein motif:HMM:NF017088.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042314 - bacteriochlorophyll binding
                     [Evidence IEA];
                     GO_process: GO:0019684 - photosynthesis, light reaction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRC-barrel domain-containing protein"
                     /protein_id="HMZ96154.1"
                     /translation="MMATHIGRRLLTASTIEGTAVQNAAGEDLGEIHSLMIDLEKGRI
                     AYAVLSFGGFLGLGDKLFALPWGALTISPGGDFFILNVPRERLEQAEGFDKDRWPDMA
                     DTAWAERLHTYYGYKPYW"
     gene            complement(29585..32476)
                     /gene="treY"
                     /locus_tag="PK063_03595"
     CDS             complement(29585..32476)
                     /gene="treY"
                     /locus_tag="PK063_03595"
                     /inference="COORDINATES: protein motif:HMM:TIGR02401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047470 - (1,4)-alpha-D-glucan
                     1-alpha-D-glucosylmutase activity [Evidence IEA];
                     GO_process: GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malto-oligosyltrehalose synthase"
                     /protein_id="HMZ96155.1"
                     /translation="MPRIPIATYRLQLNHTFTFRDAGRIVPYLYALGITDCYVSSILK
                     AVPGSMHGYDLVDPECLNPELGTKEDFAAFTAALKQYDMGLLLDVVPNHMGIRSTENR
                     WWWDVLEHGPGSRYATAFDIDWSPLKRELEDKVLLPILGEQYGAVLENQDIRLVYENG
                     GFIVTYFQHRFPVAPQSWEGILSFRLEELTARVGEQDEHVQELLSILTALRNLPARKE
                     RDPKRIAERYREAHMIRRRLAALLQESETIRVHLSATVDTYNGVKGDSASFDRLDALL
                     DEQSYRLASWRVASEEINYRRFFDINELAAIRTEETRVFQESHQLVFRLLKSGVATGL
                     RIDHVDGLYDPEHYLVQLQEWAARELEPAASGEPASLFVVVEKILGKGESLPVTWPVS
                     GTTGYDFLNLVNGLFVQSAKERSMDALYQRFVGQRIVYDDLVYLTKKLIMRASMSSEL
                     NVLGHQLNLLSEKDRQYRDFTLNSLTHAITELIACFPVYRSYITADQKDVLERDRTYI
                     MMAVNRAKRRNPTLNSQVFDFVRDLLLKRLDDRIKLAGPDQVRFVTKFQQTTSPVTAK
                     GIEDTAFYIYNRLVSLNEVGGEPAHYGLSVDAFHKALRERRAHWPHALLATSTHDTKR
                     GEDVRSRINVLSEIPERWRAALASWAKHNRRFRVKVDETVAPDRNEEYLLYQTLLGAW
                     PSTPMDQPQYEEFKKRIEQYMIKAIREAKVHTGWINPREDYEEGMKRFVQAILDRSVS
                     NPFLEEFLPFQAFVARCGMNNSLAQLLVKITAPGIPDCYQGTELWEFSLVDPDNRRPV
                     DFDQRAAILQDCQKHAGQDDVNRLALVRRLLESWEDGRIKLYLLQAGLRHRREHAALY
                     LDGDYVPLECDGVREANICAFARLHHEQAIVTVIPRLTAEVIQSDSGGAADTWQDTRL
                     TVPSWKPGSLYRNLLTGQRLETVTEEGRQVLPINQVLRDCPVALLERCF"
     gene            complement(32501..33775)
                     /gene="glgC"
                     /locus_tag="PK063_03600"
     CDS             complement(32501..33775)
                     /gene="glgC"
                     /locus_tag="PK063_03600"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: protein motif:HMM:NF002023.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HMZ96156.1"
                     /translation="MEKHGRISQPRVLAMILAGGKGTRLMPLTEARSKPAVPFGGAYR
                     IIDFVLSNFYNSGILGMHVMVQYRSQSLIEHLRKAWRIGDGERQFVTVVPPQMNSGAG
                     WYEGTADAVFQNLNLIRDFAPDIVAVFGADHIYRMDIRQMVQFHLDREADVSVATLPV
                     PVHAAQGFGIVEIDRTSLVVGFDEKPPVPKSMPGDPAHALSSMGNYLFNADVLIQALE
                     EDAKQEGGSHDFGRDILPRRLKTDRVMAYNFLDNEVPGVGYHEEPAYWRDVGTIQAYW
                     QANMDLLGDTPPCDLGNREWPIRTEPSYGPPASLVNCYVDHALIGEGTRAIEADIRRS
                     IIGRHVRIESGAYIEDSIIFDHTHIGAGAKLQRVVVDRHNTIPANVDLGPRGQERGEE
                     MDAPSEWAESGVLVIPKPQAATEEQKRRLPSY"
     gene            complement(34003..34566)
                     /locus_tag="PK063_03605"
     CDS             complement(34003..34566)
                     /locus_tag="PK063_03605"
                     /inference="COORDINATES: protein motif:HMM:NF020123.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016209 - antioxidant activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin domain-containing protein"
                     /protein_id="HMZ96157.1"
                     /translation="MIAIGREISPSTVQAYHQGEIRTLVLEELRGKWLVLMFYPGDFT
                     FVCPTELAELARLYPEFVTLGAEVCGVSTDSVYVHKAWHDSSPMVRTVEFPLIADSTG
                     ALSREFGVYLEEEGVALRGTFLIDPDGVLRAYEVHDNSIGRYIGETLRKLQAAIRVRE
                     GEGEACPANWQPGQPTLTPGLDLVGKL"
     gene            complement(34613..36067)
                     /locus_tag="PK063_03610"
     CDS             complement(34613..36067)
                     /locus_tag="PK063_03610"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96158.1"
                     /translation="MRRKTTRTAGKAVSHLVSVGVVLAMSVAYVYADRDGKEPRHTVN
                     PAIEKTKEKGFEGVDFSYDLFGGPPGQSSARLAQEAMKKDQEEKPKVMAQQARLLQDR
                     YRLECKTHSTVRMTKGKPQPIGPTVQLKNGLTWESLSQMEPEEIRKQKAFPAGFMRLP
                     HVKHEVGGMVFPEEQIHQFPRLERFDVDFDLPACFLPEFPPPIFLTTHPELGDVSQGE
                     VLSVENFDRLFRGLITPVQLDGLRMLVTQFPQEEFNLTADRKSPKPSAGVACLDCHVN
                     FHTTGQFHLNPDTRPQRDRLRLDTVSLRGMFNQQIHGSKRSLRSVEDFTEFEQRTAYF
                     NGDHIRAAKKGISIIDRLQVAHMAQIQNMIDFPPAPKLDPMTGRLDRSRADRQEIAGE
                     DLFFGKARCAVCHQPPAYTDHMMHDLFLERFGAEADGPIKTFALRGIKDSPPYFHDGR
                     LLTLEDSVEFFNVVAGLQLNSDEKAALVAFLRAL"
     gene            36299..36520
                     /locus_tag="PK063_03615"
     CDS             36299..36520
                     /locus_tag="PK063_03615"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96159.1"
                     /translation="MNCHRCSNLMFPVALQDWGGGLMNQDVAAWRCFACGEIVDQLIA
                     QNRTRGGEDAEEWRRGGARRRVNGIGLLR"
     gene            complement(36615..36815)
                     /locus_tag="PK063_03620"
     CDS             complement(36615..36815)
                     /locus_tag="PK063_03620"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96160.1"
                     /translation="MTTLLVAVVLIGMILTGLYAFGTFSTPYTEAFRFGFYLLIALAL
                     VAVVLVVGRQPFEGYDPTPNSP"
     gene            37294..38136
                     /locus_tag="PK063_03625"
     CDS             37294..38136
                     /locus_tag="PK063_03625"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96161.1"
                     /translation="MTVHMNRFLPHQGLHLATAVGISMMLSGVPVAMTSAHAAEETKT
                     GDTSQLREDAQTLLKGNRTVLATVLAVTSDQIKVDIGEVQPRFLPLKQAQQKGFPKVS
                     EGDDLIVVLNEQNLLVDYHPLDGGTSAHTIIRGELSQTLPTGHETAVIKSGGKEQSFN
                     IRSQARSKVAAIPRGATAVFLIDETNQIADVSLSRQQAAQLAGAHSQPIKGQHQQVEG
                     TVTSPLQSNHITIRTPGGTDKPYEVRDILQSKIATLHKGDAVVLLIDGDNKVIDVAIP
                     PKGK"
     gene            complement(38169..39536)
                     /locus_tag="PK063_03630"
     CDS             complement(38169..39536)
                     /locus_tag="PK063_03630"
                     /inference="COORDINATES: protein motif:HMM:NF025885.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ96162.1"
                     /translation="MTQARILIVDSNVGAATVLRDMLSVDGYEVSAVRDPKDAGGYLE
                     RIPVDLILTDLPPETEELTCLRQLRGLCPTTPIVLMTAHGSLRTAVEGLKAGAFDYMS
                     KPFTAEEVRSVARRAVEHTHMRAEQAASGEAAPDDTSPFASLVGSSPAMVQVYKAIAR
                     VAQTDSSVLLQGESGTGKELIARAIHASGPRSSGPFVTVDGGALADSLLESELFGHER
                     GSFTGAISSRKGLLEQAHSGTCFLDEVADLSPALQGKLLRVLQEKEIRRVGSTATTAL
                     DVRIIAASKLPLEPLVRAGTFREDLYYRMNVVTIDIPPLRERLDDLPLLAKRFLRLYG
                     SMKMPPVTELSAEALALLRRYWWPGNVRELEHAIERAVTLSPYSVICPEDLPPAVKDA
                     QPEGLARAQGWVTLEDLERNHILQVLDSHARDLGRSATILGIHRKTLLRKLRHYGLAA
                     GYGVA"
     gene            40085..40690
                     /locus_tag="PK063_03635"
     CDS             40085..40690
                     /locus_tag="PK063_03635"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96163.1"
                     /translation="MKRWLACCASVIVTAIWFPCSSGALEFTADRVTHTDRGFHRARI
                     FYHDGMWRLEHNERGPVSITIVRLDRNQVWHLLPVTHHYKTVSYDRDYALHLATTLDH
                     EISRETIGVQILDGHPTVLYEVLTITPGGGRESYYQWIATDINFPLKLAKKNGDWMVE
                     YRHVKFGPISDVFFELPRHYAPMDDDQHTASSPEPVRRMSP"
     gene            40687..41244
                     /locus_tag="PK063_03640"
     CDS             40687..41244
                     /locus_tag="PK063_03640"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96164.1"
                     /translation="MTTRTSRHQMTGARDHIVIGLLPNMGAVREALEALRARGISDDQ
                     IGLAMRQAEERLSDEESPSPTAQDATTGMVGGGLIGGLAGLLTTTGVVAIPGLAPLLA
                     GGSLIGLLGATGASIVAASGLGAVAGGLVGALISINVPETAAKHYADAVHEGQILISV
                     KTDGDPAQVEELLASLGATTDRQSP"
     gene            41371..42240
                     /locus_tag="PK063_03645"
     CDS             41371..42240
                     /locus_tag="PK063_03645"
                     /inference="COORDINATES: protein motif:HMM:NF012692.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HMZ96165.1"
                     /translation="MAKQQASRTKSNTPAAQKVVSQNGSAEPPVPHHEPIKTLVVDIG
                     GTGIKSMIVNEVGEPIGERLRLPTPKRKTPPSVLKTIHRLAKLSGRFHRVSVGFPGTI
                     RNGVILDAVNLDPSWKHFNLIAALGKTLRKKPVRAANDADVQGYGAISGKGVELVLTL
                     GTGVGSSLFIDGRLVPNLEVGKNRLRGSELERIGKKLWNNRLLKVIAKLEKMFHYDRL
                     YIGGGNAVQVDIGRVPGNVTVVSNLNGLLGGIALWEEAAHFAASRQELANNNANHSAP
                     PKPAAERAAPRGR"
     gene            42625..43305
                     /locus_tag="PK063_03650"
     CDS             42625..43305
                     /locus_tag="PK063_03650"
                     /inference="COORDINATES: protein motif:HMM:NF022072.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SRPBCC family protein"
                     /protein_id="HMZ96166.1"
                     /translation="MGDKERLISGLVGGGLLLHSLRGPFSGLSALKALLGLALVQRSV
                     TGHCAGYHMLGMNTHDQTDTSSIGRSKVHSDRAIKIERSITIQRSAKELYAFWRQLDN
                     LPTIMSQVRTVEPLDDRRSHWVINTLPGAPTVEWDAEIINEVENERIGWKTLDGATVE
                     HAGSVRFTPLNDERQTRVTVTLQYDPPAGAIGAAIADLFGQEPGQKIARDLERFKEAM
                     ESHTTVSQ"
     gene            43375..43695
                     /locus_tag="PK063_03655"
     CDS             43375..43695
                     /locus_tag="PK063_03655"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96167.1"
                     /translation="MNMWRGLTVAVMVMGATVISGVPGGAAQKESMEKTPKVEDDTSD
                     KSAGKASKDKVIKKRRSSGKSNAEDTTDAKSQPKSQESREGTPGTTLMFRSDGAGNSG
                     AAGK"
     gene            43746..44873
                     /locus_tag="PK063_03660"
     CDS             43746..44873
                     /locus_tag="PK063_03660"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96168.1"
                     /translation="MPKQNRHIRLFAAMLGLGIMSATGVYADQAREQREAGLQGQSDG
                     RVHNADITGGFYDDRYKLDDWYYDFYDSPGYSRADSTSVIQASNENTATMADAAHPSL
                     RHHRPYRTDQNVPATPYAGDPWFYAQRDPMYGIPETSSDAYGGNVIKGTIKAAKQVRN
                     RTTGDQNTVVLLTTPDRRQVTADLGSSRRTMDLALTKGDSLVVAGPWEDVGPYSVLMA
                     QQIRTEAKRVTLNRPIGAARGDRTVEGRIQQFRDIRMNRSGELHRAAAVQTPDGRMAL
                     VDLGPDNQDRTPLRAAAGDRMVAQGPVVQVGNYPVLWANRVAINDGMPVDVTRTTAPT
                     DFVPATGNRQENCLGAGCDNQPLNQGQPGNRNSNAMDGTTR"
     gene            complement(45091..45441)
                     /locus_tag="PK063_03665"
     CDS             complement(45091..45441)
                     /locus_tag="PK063_03665"
                     /inference="COORDINATES: protein motif:HMM:NF021568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na-translocating system protein MpsC family
                     protein"
                     /protein_id="HMZ96169.1"
                     /translation="MAQRSTNKADLEYALMMTILNFHTEFMRSNYANVQVHLSQDEIE
                     VTLTRQGSVPAERRLAESPEGRSLLRQVHEAMFLSCERILRERIEPVVERKVREMVTS
                     LDPVSGRSSITIRL"
     gene            complement(45662..46021)
                     /locus_tag="PK063_03670"
     CDS             complement(45662..46021)
                     /locus_tag="PK063_03670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014960950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate dehydrogenase"
                     /protein_id="HMZ96170.1"
                     /translation="MATTFSEAAKATRKKKVIKLVGVDMYIVTEEGIPKFPDGEFGPF
                     KCEFISNRGTKVWPGFVSPDLMMVNWYRCRFMATGDVTDADVDTFLAVLTKKGWWWSA
                     AQKLWTHDGEPAFSKAY"
     gene            complement(46057..47070)
                     /locus_tag="PK063_03675"
     CDS             complement(46057..47070)
                     /locus_tag="PK063_03675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014448976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate family dehydrogenase"
                     /protein_id="HMZ96171.1"
                     /translation="MAQHVVTMLPGEGTGPEICEAVRLVIDASGVDIKWEYEEIGLGC
                     LEKYGTLLPDKTIKNIAKNKVALKGPTTTPVGTGHKSANVTLRKVFDLFANVRPAKLI
                     PVLKRPWDKIDIINFRENTEDSYAAIEHMVSDEVAQCLKVITWPGSYRIADFAFQWAR
                     ANGRKKVYCVHKANIMKMTDGLFLDAFREAAKKYPEIETGDVIVDNCCMQLVRNPAQF
                     DCLVLPNLYGDILTDLCAGLVGGLGFAPGANIGDNCSIFEAVHGSAPKYAGMKKVNPS
                     AVLVSGIMMLRWLKETAAADRIEKAMFAVLHEGKHVTYDVGGTATTDEYAQAIVDKMQ
                     GKA"
     gene            complement(47322..48713)
                     /locus_tag="PK063_03680"
     CDS             complement(47322..48713)
                     /locus_tag="PK063_03680"
                     /inference="COORDINATES: protein motif:HMM:TIGR01499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HMZ96172.1"
                     /translation="MRGRRTKTCPPSWTVPFSSYAEVTEFLRGVEVDCILRGQPSDGT
                     VSLGAVARCLHELKRPDLAYRSIHVTGTNGKTTVSRMIGALIRATGLTVGVYTSPHVT
                     NFRERIAINGEPIGEDELVDACNHVKAFLDVHGLQLAPFEFLTAAAFFAFRAAKVDYA
                     VIEVGIGGRQDATNVIAPELAVITTVEYDHADMLGDTLEQIAGQKAGIIKPFTPVLCG
                     PMPEGPRAVVLSRAAALKAPVLLSGQDYEVTEFIRDGYAGLCTVRVGASTHPQLRLRS
                     PAAFMAANAAHALMAYDVLRKRGLLPDIDPDEIGRVFEKTEWPACCEVLSGTPAVLLD
                     GAHNAPAAMRLATILRTTFEGRRSVLLVSLARDAQWEQVLRALAGAGADRLIVTGGPQ
                     DRAVPPDAIAEQWRTCSSVAAEVVDSTEAAFRRAVQAAGPHGVVAVTGSPQLAGYCRP
                     LAKTFPAQALVQP"
     gene            complement(48752..52033)
                     /locus_tag="PK063_03685"
     CDS             complement(48752..52033)
                     /locus_tag="PK063_03685"
                     /inference="COORDINATES: protein motif:HMM:NF021578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2309 domain-containing protein"
                     /protein_id="HMZ96173.1"
                     /translation="MHTTNGSDQRHRDAQRMELRSYVSLAGETIAKVWPMTSVIARNP
                     LQGFEHLRFDEAVERAEQLFGGSGTLSGEAFREAFRRGRIQEKHFEEALRGQAGDRQI
                     TFGDRQVTHLDVLRAIMVAVGRDHDRVGTAATAPPTPTGDSVTVPHLAAWLGRMLPRE
                     TLETERAAGLQYIPGEWPCESTMADWCDRTLGVTITDEINRQMIKWCAAFCDEGEAAW
                     PMPKREETFFRAWKAAARYDFSLRCAGVERAASKIAALADRPEDVLLESLEMLHIPHA
                     IWQSYLSRHLAALPGWAGFIKWREDQDAHVWQSVYRIDLVKYLAVRLFYERELVATAC
                     RASLGCEGTASAVLEYGKRYPYTLWFRRASMSGDLPSALLPEASRLQRAGRSYDPAAW
                     EQDCRRWFEEQPAGERTYRVEAQNLVSLSGALAVPVHEITSTSPGDLAMLLRWMREFT
                     PAKQRVAWLEAFERSHQCEVLRKLELPAGEDARIAAPGAMTARPVAQFVFCIDVRSEV
                     FRRHLENRGGYETYGFAGFFGVPFSYRSLDEQRELPLCPVLLKPKHLIREVPRTYQDA
                     MAERRKHSSHLVKAGHELLHDLKHNVVTPYVMVEALGWFFLLPFLGKTLCPRWYHRFA
                     AWVKSWVVPPVATTLTVDKFSTADAENMLAAEQRLQIAWWLRKHGQRAGSLVTGAVLD
                     EVRRQALEEDEESASHPGALGRLLGVCSTEETDALVTLRRECRLTYRGTRSRLDRITR
                     TGFTVNEQAYYVETSLRLMGLTGSFARLVVLCGHGSTSQNNPYESSLDCGACGGGQGL
                     PNARAFAMMANRPQVREILASRGLTIPPDTQFVAALHDTTTDRVQVADLEDVPSTHRK
                     ELAQILDDVHEAGGEAAAERWVALTAAESHEGTRAARQELERRSVDWAQVRPEWGLSR
                     NSVFIVGSRRLTREADLNGRSFLHSYDHAMDGDGKLLEIIMTAPLIVAQWINMEYYFS
                     AVSPEVFGSGSKIYHNVTGGIGVMTGSQSDLRMGLPTQTVMRGEAPYHEPMRLTAIIE
                     APRERLSAIIERQPLLEKLFNNRWLLLIACEPAEAKYYRYDGGKWFVVADMAEQVGEA
                     PVPQA"
     gene            complement(52282..53079)
                     /gene="cysD"
                     /locus_tag="PK063_03690"
     CDS             complement(52282..53079)
                     /gene="cysD"
                     /locus_tag="PK063_03690"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009336 - sulfate adenylyltransferase
                     complex (ATP) [Evidence IEA];
                     GO_function: GO:0004781 - sulfate adenylyltransferase
                     (ATP) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0019419 - sulfate reduction [Evidence IEA];
                     GO_process: GO:0070814 - hydrogen sulfide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="HMZ96174.1"
                     /translation="MRHLRELEDQSVYILREAYKHFDGLAMLWSMGKDSTVLLWLARK
                     AFFGHVPFPLVHIDTGYEMPELIEYRDRICRDWRLNLIVGQNKAALADGMGPDRGRVV
                     CCTAMKIDALNQTIAQHGWSAIILGIRADEEGTRAKERYFSLRGKEGEWNFRDQPPEL
                     WEQFQTKFPPGSHIRVHPLLDWTELNIWEYLEQERIELPSPYFDRGAGTRYRSLGCVP
                     CTGTVDSCASTIPQIITELRRTTTAERAGRAQDEGRGMETLRKLGHM"
     gene            complement(53417..54829)
                     /locus_tag="PK063_03695"
     CDS             complement(53417..54829)
                     /locus_tag="PK063_03695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ96175.1"
                     /translation="MAWHLLLLEDEASVREAFALRLRDKGYVVQTAETGEEALGLLRS
                     FEPDVLIVDLVMPNLSGLDVLARVKQMSPALPVIVLTARGTVKDAVEAMRLGAFDFVA
                     KSIDMDDLLHTLRRVTDFLTLQRQVQLHSGQDAARYALDRVIAKSPVTKSFLAQVQEL
                     VRNDRVTVLLQGETGTGKQYMGRVIHYNSARGSKPCVEVDCPSIPRDLFESELFGHEK
                     GAFTGAAGRKCGLIEMAEGGTVFFDEIGDLPLALQAKLLRVIEERSLRRVGGMNTVPV
                     DVRFMAATNRDLKAAVAKGEFREDLYFRLNVVMLTVPPLRARPEDIIPLAEHCLLRSA
                     LALKKPVRELTESARQLLQAYHFPGNVRELGNLIERAVIFCNGPSLDAAHFPADLAAA
                     VAPASLPGLPGAVQPTAAPAEADPLMVSLSFKVGERSLSDLEDAIIQAVLERSDGNKT
                     LAAKHLGITRWMLDRRRKAY"
     gene            complement(54910..56883)
                     /locus_tag="PK063_03700"
     CDS             complement(54910..56883)
                     /locus_tag="PK063_03700"
                     /inference="COORDINATES: protein motif:HMM:NF024883.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ96176.1"
                     /translation="MASSRRSPTTRSRPVQSEIAAAEVLAWLSDCIQGGLSFVCKGIL
                     IFENSQFAELVESGLPRVEGHEHALRKRLLDDAIAWNNRPLGERKSVEYQLEGRDGGR
                     LYYVCRFNVVPYRGERGVLMVLEDVTERVMLAQDASHVARFQSVLARIGTLAVSGVSA
                     QELMNEAVKETAAALEVELCKILVPRAHDGQLYIMAGSGLQSELIGKLTIEGGTHSQA
                     GYAIAKRLPVVVDDLRRETRFSPSRLLTEHGAVSGMCVPMLVEDRVYGVMTAHSKRVR
                     KFSQQEQEFLCTMANTIGTVLERRWHEETQMDFYHRLFLSAQDGVMMTDTTGRILEWN
                     PALERMTGWTREEALGQRPAILKSGKHPPEFYDRLWASIRAGQPFVERFVNRRKDGSE
                     FLVWESVNPVKASDGTTQYFMAILTDLSEREQMLEALRHTEQVKLVGQLAGGILHEVR
                     NPLIGLGSLATHLADQASLPQEARDRCRLIAREAARIDELLESHLGQLRPRPFDITSC
                     DLASVLDDMLTLLRPNIVKNQILIKTSVAPDLPSVDASKAHILQVCLNIVLNAIDAMP
                     GGGHLHVTLVPEARRVPGVLMRFADTGKGIPADDLERIYEPFFTKGKAKGVGLGLTIT
                     RDMVERHHGQLVIQSPPGRGAVVDVWLPLKHEA"
     gene            complement(56996..57319)
                     /locus_tag="PK063_03705"
     CDS             complement(56996..57319)
                     /locus_tag="PK063_03705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HMZ96177.1"
                     /translation="MLTLHPMKEIRIVVEGEHLKIVTSLLDRVGATGYTIINNVSGKG
                     HHGFHEGHLLFNDTSSQVIVFTVVPEERIEPILAGLGPLFHKHSGAMFVSDVAVTRRD
                     HFVTP"
     gene            complement(57337..60693)
                     /locus_tag="PK063_03710"
     CDS             complement(57337..60693)
                     /locus_tag="PK063_03710"
                     /inference="COORDINATES: protein motif:HMM:NF021578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2309 domain-containing protein"
                     /protein_id="HMZ96178.1"
                     /translation="MAIETRAFTEAQRMELRSHVELAGEAIAQYWPMRTFIHHNPLHG
                     MEDMPFPQAIKRGEHLLGGKGYLSNAIYRRFFEQGRIGLNDVSCVLAPLASDRCVTFA
                     GRELTHLELMRVSMVHGLVDLPAKLQDSGAAGDTALDDLLAWLGTAVAGTRIRQPEPL
                     VPWESLDLLSHETLSAWCDQTLGTCIVSDINEQMIKWCSVFLDEGEASWVMPNREQTF
                     YRAWKRLARYDAGLGLLGIQDAATKIDALGERPEEAVLSCLVDLGIPKSAWEAYFALH
                     LSALPGWAGYIKWRAEEQHHPWQVRYPIDLVKYLAVRLFYEREFVEYHCRRALNRPGQ
                     YDAIRAILDQAPYAHWLRRQLTARTIPPWAIREAEEWRRSHQAATLDEWNQVGSRLYE
                     QTSEWRGTEAMKRDARRLLALAAALGTDPALISQTSVADAATVLNWLDGFPAGQQGQR
                     WLEALEAKHRRDVVDELRAVTKQLRATDDRAAPAGSARPLAQMVFCIDVRSEVFRRHL
                     EQLGGYETFGVAGFFGIPVKYQAFGEEHPVTHAPVLLKPKNHIREIPRSYHGAAASRH
                     RLFAQLSHVAHTLLHDLKENVITPYVMVEALGWFFSLPFFGKTLCPLAYQRLTSSLKS
                     LWVPPLATTLTIDKLTREEAEEMVAVEQRAVIRAALRQEFPALGSAITPALIDAIRVG
                     VMEDAEGQRGGDVAHILGISPVEVAALYERFRRDFNLTPRGMSSRLQRITQHGFSVSE
                     QAYGVEAALRLMGFTSGFSRLVVICSHGSTSDNNPYESALDCGACGGNSGLPNARAFA
                     SMANNAAVRKVLETRGIRIPGDTHFLAGLHDTTRNDVRIVDMEDIPATHRKDLVRLLE
                     DLREAGAQAAQERGLALGGPVATWSRKDPHTKAARRSVDWAQVRPEWGLSRNNLLIVG
                     RRELTRPLNLQGRAFLHSYDHRQDSSGKLLEAIMTAPLIVAQWINMEHYFSTVDNEVY
                     GSGSKVYHNIVGRVGVMSGANSDLRLGLPAQTVLDGSMPYHEPMRLLTIIEAPRTRVE
                     SVIATHPGLERLFHNEWVLLVVCEASEGAFYHYDIMRGWQPVSGLPEQSSAAAPRFVR
                     ESAPFLHQKDGETVGSVQEATAFEQKRMNP"
     gene            complement(60730..62394)
                     /locus_tag="PK063_03715"
     CDS             complement(60730..62394)
                     /locus_tag="PK063_03715"
                     /inference="COORDINATES: protein motif:HMM:NF012581.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proton-conducting transporter membrane subunit"
                     /protein_id="HMZ96179.1"
                     /translation="MMEAIFPLVTILAPLFGTLSIALFWREMGERVSRLGIGALWASA
                     LTSLVTLALVSYGDPIRLTLAGAPSGAWSYTILVDRLAAVMMVLISSVSLVIHVYSER
                     YMVGDAGYTRFFALLGSLTFVLLSLVSSGNLLWMFACWHLVTWLLATLLVCNPASLAA
                     RDAGQKTFWVQSLGDAAFALVLLILYGSYGTLDVTELFPRVQAAPVTSWSGLALELNV
                     PLVTTLLLVLSVMTKSAQFPFHFWLIGTIEAPTPVSALMHAGIVNAGGFLVNRMAPLF
                     GLAPTTLHLLFVIGGLTALIGASAMLTQSSVKRTLVYSTMGQMGYMVMECGLGAFALA
                     VFHLCAHGLFKATLFLNSGAQIHKARTEFKLPPGNRVEESRAFSPMTWTTGLAVTLVL
                     PLIILLVAHGVVSIPLQESQGTVIFLFFGWVTTSQAMFSLYRLHAGASWNVSLTMLGA
                     LALIGLTYLWAGEAFTHFLYPAHGIAASYVQAAEWNRALFDAVVGVSAIMIVGAWGLI
                     YGKAKGIKVLMPGWMESLRTRAYVAFLNGLYIEDMVRMIGRAGSRR"
     gene            62766..63263
                     /locus_tag="PK063_03720"
     CDS             62766..63263
                     /locus_tag="PK063_03720"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96180.1"
                     /translation="MLSAGQIRTSERRRIAHVLRGWMILWLLALPLFHIHPETDPHHG
                     EAGHVHAAAVHTVFSGDLEGEFGEHQETASVRPHPGEGPAVSAEGAHAWSSDPELNLS
                     LLNDATDRKLAKPLLTHLLFVAHHLVPLFDQQDGPHGEPLSSTVTMLFTRDVPARAPP
                     SPFFS"
     gene            63367..64617
                     /locus_tag="PK063_03725"
     CDS             63367..64617
                     /locus_tag="PK063_03725"
                     /inference="COORDINATES: protein motif:HMM:NF014385.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HMZ96181.1"
                     /translation="MMPRMVLSLLMACVFSQSGALSWAGEERPRAYSLSDVLTFAAQH
                     NPVLAGAEGLVKQSQGQQIAAGAYPNPSITGIAGRGAIRDPSTGTHVTERTLTVEQPL
                     EWTGKRQARQEAADAGLAGANAALEDARLSLLADVKIAFYHLLFGQRDVELSAQNVTN
                     VEEVLRTVQARVTAGEATSFDSLKAGVEVQKAKKEVARANNALLVARARLNTLTAGTL
                     GKEFSVQGDFDRPKQSLNADGLTAQALEQHPAVRRLSKLAEQADHTLRFEREARVPNV
                     SVIGSYHREAGDESLTAGLAVPLPLWYRRQGEIQSALGAKHRADAERLRAQQELEQAI
                     TQHAQEVRTAQEQLQVFETGLLKQAEQTLTVARTSFRHGAASLLDVLDAQRVYRQTQL
                     EYAQVRADLSIALARLERALGTSL"
     gene            64655..65818
                     /locus_tag="PK063_03730"
     CDS             64655..65818
                     /locus_tag="PK063_03730"
                     /inference="COORDINATES: protein motif:HMM:TIGR01730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HMZ96182.1"
                     /translation="MTRRLMTIGMVPALLWLLSGCSDQGTPPPKPATTGEAQTITGSS
                     KAIHPPPAVQARLRSEPAALRAVPTLITAPGEVALDLKQVAKITSRIGGQVERIHVQL
                     GDRVKKGQALVAIGSLQLDQLIEEYLVGKAQADVAENSFRRTEKLRADDIVTERKLIE
                     DKGLYLETQARYQHIRERLSNMGISTDDLKQGPHEKSHLYTLTAPIAGTVVIQNAVRG
                     QGVGPGDELFEIVDTSRVWVFANLPIEQARQFKEGDSGTITPKGGEAIVAPLTYLSPV
                     ADETTRTIRVRFEVANLQGQLKPREYVEVALGWSGAPVITVPMTAITTIDKTRGLFLD
                     TADGYTFVPVDAGREGGGWVEIRRGVKEGDRIVTDGVFDLKNVLLKEHIGSGE"
     gene            65826..68948
                     /locus_tag="PK063_03735"
     CDS             65826..68948
                     /locus_tag="PK063_03735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051139 - metal cation:proton antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CusA/CzcA family heavy metal efflux RND
                     transporter"
                     /protein_id="HMZ96183.1"
                     /translation="MQQLLTFSLRYRFFTLVAIVVVIASGLWSFAHLTIDAVPDLTPV
                     QVQILTRAPALGPVEVEQFVTFPIEASLNGLPALRELRSISRYGLSAVTAIFDDRTDI
                     YRARQFVAERLAQAMERIPAEYGRPVMGPLTTGLGEVYQFTVKGEGFSPMALRTLLQW
                     DIGMKLRAVPGVVEVNIWGGDPQQFHVIVDPSKLLSFKLSMKQVFDALQRNNAIAGGG
                     YIEHQREQLSIRGEALATQLSDLAQIVVAHGPGGVPIYIADLAEVKEGSALRIGAATA
                     MGEGETVIGMVQMLAGENAQEVVTRVKARVQDIQATLPAGVTIEPYYDRTIFVSKVMQ
                     TVRNNLLEGGLLVIAVLFLFLGDLRAGLIVASAIPLAMLIAFIGMMQAGLSGNLMSLG
                     AIDFGLLVDGSVVMIDNILRRLGEKPPPTREARLKEVLAAGQEVLRPMTLAVTIIILV
                     YVPILALTGIEGKMFRPMAVTVIMALTGSLFLALTVTPLLSFWFLRATPGSETTAVIR
                     GVRRVYAPWLQRAVARPIWPVSIAVGLFAVSLVAGSRLGIEFVPRLEEGDLAVQVWRL
                     PSISLSESVTTALDIERVLRRFPEVTRVVTRTGSPEVATDVMGVEMSDVFVILKPQRD
                     WVTAHSRNELIEAMKRQITDQVPGVGLGFTQPIEMRFNELIAGVRSDLAVKIFGPDLD
                     ILKQQAERAARALQHVPGAADVKVEQVAGLPLLRVVVDRAEIARYGLTAEEVLTLVQS
                     ARVGTIVGTVVQGSRRFELVVRLADRVSRDPGSLGSLLIPTMHGELVPLSRVTSILVD
                     SGPAQVSREHVQRRIVVETNIRGRDLGGFVSEAQQAVAQAVTLPPGYELIWGGQYEHL
                     QEAGKRLAMVVPVTLMLILGMLSVIFGTLRPALLIFLNVPLALSGGILALWLRGLPLS
                     ISAIIGFIALFGIAVLNAVVLVSHIRQLEAEGVSTREAVLHGAMDRLRPVLMTALVAS
                     LGFLPMALATSMGAEVQRPLATVVIGGLLTSTALTLLVIPALYSRLVPQAASRPHPAA
                     VQADDSAIQV"
     gene            69141..69506
                     /locus_tag="PK063_03740"
     CDS             69141..69506
                     /locus_tag="PK063_03740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ96184.1"
                     /translation="MATIMVIDDEPSIRGLLREVLERSGHKVVEAKDGREALDLYQKH
                     KADLLIMDLLMPEVDGLEATLQLTREYMDTKIIAMTGAQGDRNFLDIARLFGAHRTFE
                     KPFDLKEMLNAVEAELAQK"
     gene            69679..70077
                     /locus_tag="PK063_03745"
     CDS             69679..70077
                     /locus_tag="PK063_03745"
                     /inference="COORDINATES: protein motif:HMM:NF016763.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HMZ96185.1"
                     /translation="MLIVLVGILPLHNFVGHAHWQYIRWVPTPDQLSSPAILLDLAFD
                     AVANILLFVPFGLLYALRGLEGKPLSPRHLLLMAFALSFSIEYYQVYCHNRSTSLLDL
                     LDNVLGAYLGMKAGEVYIRKNASAVVEPAA"
     gene            complement(70080..70487)
                     /locus_tag="PK063_03750"
     CDS             complement(70080..70487)
                     /locus_tag="PK063_03750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper family protein"
                     /protein_id="HMZ96186.1"
                     /translation="MACLCVLGLVLSGCAAPKPILYPNAHYQQVGADAAQADIQDCMA
                     LAKEAGASSSEGKTAQVVTGTVGGGAVGSAAGAVGGAILGHPGRGAMVGAASGATAGF
                     LRGLFKRSPPGAAFTNYVDRCLRDRGYDPTGWQ"
     gene            complement(70567..71424)
                     /locus_tag="PK063_03755"
     CDS             complement(70567..71424)
                     /locus_tag="PK063_03755"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96187.1"
                     /translation="MFKIKKKIEKPKPPILYNVIEDYSEFDAPGNVTVCAMTLPEDLA
                     AHAKILAESYDVPLEQMLQLLTDGGVYVYPQVGGLLTRGLFACRVDPTGASPKQTWVL
                     DLMQFAEAEQWARARAVSLIDAAGEIFYRTLPEELKTKLAQKNLGLDYRTLDRAVAKG
                     GDIKFIDFRKDWSPHFKRLCIMPDGRLVETGGLEEFAQLHQITMPQAKKLVEEGGTMD
                     VAGGEVLACQIVNGQPAVARFSAKNYAKAKELVTAKGLHIMDALSEVAYNDSVMMRTL
                     QRKDLGGRI"
     gene            complement(71490..73235)
                     /locus_tag="PK063_03760"
     CDS             complement(71490..73235)
                     /locus_tag="PK063_03760"
                     /inference="COORDINATES: protein motif:HMM:NF013077.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="HMZ96188.1"
                     /translation="MTLDQPSSGASAGTTSTDPIDRVIAYHIRTKHHFNRYARSLGFL
                     DWANQPNPFRRFEGAQLIRLPLLSPDDDPQSPSYDALYQPGAVASRPLTIKTISRFFE
                     LALGLSAWKRAGESEWALRSNPSSGNLHPTEGYVIVPPVDGLDLPPGLYHYAAKEHGL
                     EFRAGLPSGKITQLLAPFPDGAFLFGLSSVHWREAWKYGERAFRYCNHDVGHALGSAR
                     IAAATLGWRMVLLDGVEQNQVARLLGTHRQEDFGEAEPEHPDCLAVIWPSPNMKHDVQ
                     NLPLGVDQTVVKDLAPGPWHGHANLLSREHGVHWEAIDEAAEASWKTGEERLVVSLPV
                     EPPVHSEPRHDPQATRGAATIIRQRRSAVSFDGRTAISSATFFQILLRLIPHASQPQL
                     ARPMPWDLLPWDPAIHLLLFVHRVEGLTPGLYVMARDAKKLPLLQQAMNPELEWTPVP
                     GCPTDLPLYWLLQGNAQRLAAQVSCHQGIAGDSAFSLGMLAEFEGRLRQGGAWWYPRL
                     FWEAGLVGQVLYLEAEAAGVRGTGIGCYFDDPVHEIVGIKDLTLQSLYHFTIGGPVDD
                     GRLLTLPAYYHLQRG"
     gene            complement(73284..73979)
                     /locus_tag="PK063_03765"
     CDS             complement(73284..73979)
                     /locus_tag="PK063_03765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT1/CCC1 transporter family protein"
                     /protein_id="HMZ96189.1"
                     /translation="MPATPHSEKHFTATATVRDIVIGMADGLTVPFALAAGLSGAVAS
                     SALVVTAGLAEIAAGSIAMGLGGYLAAKTDLEHYAAERKREVRETEHIPETEAEEVAE
                     IFRGYGLRDEHIAPLIASLRANPRRWVDFMMRFELGLEEPDPARARSSAWTIALSYVI
                     GGLIPLLPYMVFHEIATALWWSIAVTPVALFVFGYVKSGLTGVPPWRGGVQTVFVGGL
                     AAAAAFGIARLLG"
     gene            complement(74240..>75075)
                     /locus_tag="PK063_03770"
     CDS             complement(74240..>75075)
                     /locus_tag="PK063_03770"
                     /inference="COORDINATES: protein motif:HMM:NF020252.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="HDOD domain-containing protein"
                     /protein_id="HMZ96190.1"
                     /translation="QSCSNVFTLPEIYFRVRDVVDNPDSTMDDLAQVLKMDPAISARV
                     LKIVNSPLYGFPKQVDTVTRAVNLLGMQAVRDLVTATTVGRSFSGMTVQIMDLSAYWR
                     KSVLCALMAGKIAKACGIEDSERFFIEGLLRDIGHLVLYQTIPERAQSALIEAGNLGE
                     PLAEVEQSNFGCDFTEVGAELVHSWGMPVQIEQAIRHQLCPEDAGDFSLHASMVHLAG
                     VVADHYELSPTRAPKDLPFQATALQTTRFNAEDRPMLLQEALDQLQDTVKLFSPAAMA
                     A"
BASE COUNT        15579 a        23139 c        21024 g        15333 t
ORIGIN      
        1 gttcgatctc ccgattcttt cgttcgacct ccgcattctg ctcggccagt tgctgcgcct
       61 ttttcgccag ctcctcgttg gtttgttgaa gttctttctg ctgcgcctgt aactccgtcg
      121 cgaggttctg tgactgctgc aacaggcctt ccgtttgcat cgtcgcttca atggtattga
      181 ccacaacgcc gatcgtttcg gtcaactgcc cgagaaacgc cacgtgcgtc ggagtaaatt
      241 ccgacagcgt ggcaagttcg atcaccgcct tcgtctgccc ttcgaacagg accggcagca
      301 cgatcacgtt gcgggcgcgc gcctggccaa ggccggagcg aatccgtata tagtcagacg
      361 gcacatccgt cagcacgatg cgccgctttt cccgcgcgca ttgtgccacc aatccgcctc
      421 cgatccgcat atcgtcagac accaccgttt catccgcccc ggcatagctg gccaagaggc
      481 gcaagagagg tttgtccgcc gtatcgcgct ggtagatggc gccatattgc gcgttgacca
      541 gcggggccag ttcgctcagg agcaaatcgc ccacggtggt caagtcccgc tgtccctgca
      601 tcatgcgggt gaatttggcg agattggtct tgagccagtc ctgctcggta ttctgatccg
      661 tggtggcccg caacgtccgg atcatgacgt tgatgttgtc tttcagctcc gcgacttctc
      721 cgcgcgcctg gacctgaata gacctggtga ggtctccctg cgtcaccgcc gttgcgactt
      781 ccgcgatcgc acggacctgt gtggtcagat tcgccgccag cagattcacg ctctccgtca
      841 gatctttcca ggttccgggg acgcccggca cgatggcctg gccgccgagc ttgccctcgg
      901 tacctacttc cctcgcgacc cgcgtgacct cgctcgcgaa ggcgctcagc tgagcgacca
      961 tgcgattgat cacgtccttg atctgtagaa tttcgccgcg cacgtcgacc gtgatttgtc
     1021 ttgtcagatc gccgttcgca atcgaggtcg cgacgttcga catatcccgc aattgcaccg
     1081 tgaggttgct agccatggcg ttcacgctgt ccgtgaggtc tttccaggtg ccggccacac
     1141 caggcacgac ggcctgcccg cccagcttcc cttccgtgcc cacttcgcgc gccacccggg
     1201 tcacttccgc cgcaaaggcg tttaactgat ccaccatcgt gttcgtcgtg tccttgagct
     1261 gcagaatctc gccacgcacg tccaccgtaa tcttcttcga caagtcgccg ctcgccacgg
     1321 cgatggtgac ctccgcgata ttccgcacct gggccgtcag gttgctggcc atggcgttca
     1381 cgctgtccgt gaggtctttc caggtgccgg ccacaccagg cacgacggcc tgcccgccca
     1441 gcttcccttc cgtgcccact tcgcgcgcca cccgggtcac ttccgccgca aaggcgttca
     1501 attgatcgac catcgtattc gtcgtgtcct tgagctgcag aatctcgccg cgcacgtcca
     1561 ccgtaatctt cttcgacaag tcgccgctcg ccacggcgat cgtcacctcg gcgatgttcc
     1621 gcacctgggc cgtcagattc cgcgccatgc tgttcacgct gtcggtgaga tccttccagg
     1681 tcccggccac cccgggcaca atggcctgcc cgccgagttt gccgtcggtg ccgacttcgc
     1741 gcgccacccg cgtgacctcg gccgcaaaac tccgcagctg gtccaccatc gtgttgatgg
     1801 cctctttcaa ctgcaaaatt tctccatgca cgtccacggt gatctttttg gacaagtcgc
     1861 cgttggccac cgcaatcgtg acattcgcta tgttccgcac ctggtcggtc aggttgcccg
     1921 ccatgagatt gacgctgtcc gtgagatcct tccagacgcc gctcacatcg cgtacctggg
     1981 cctgcccgcc cagcttgcct tccgtgccca cttcccgcgc cacccgcgtg acctccgccg
     2041 cgaaactcct caattgatcc accatcgtat tgatggcttc cttgagttgc agaatttcgc
     2101 cgcggacatc ggccgtaatt ttcttcgaca gatcgccgtt ggctaccgca attgtgacat
     2161 acgcaatgtt ccgcacctgg tcggtcagat tactcgccat ggagttgacg ctgtccgtga
     2221 gatccttcca ggttcctgcg acgcctgata ccgcggcctg gccgcctaac ttgccttccg
     2281 tccccacctc gcgtgccacc cgcgtgacct cggcggcgaa gctacgcagc tggtccacca
     2341 tcgtgttgat ggcttctttg agttgcagaa tttcgccgcg cacgtccacg gtgatttttt
     2401 tggagaggtc cccgttcgcc accgcgatcg tcacttcggc aatgttgcgc acctggtcgg
     2461 tcagattgcc ggccatgagg ttcacactct cggtcagatc cttccagaca ccgctcacat
     2521 cccgcacctg cgcctggccg ccgagttttc cttccgtgcc cacttccaga gcgacgcgcg
     2581 tcacttcggc cgcgaagctg cgtagctggt ccaccatcgt gttgatggct tctttgagtt
     2641 gcagaatttc gccgcgcacg tcggccgtga tctttttcga caagtccccg ttcgccacgg
     2701 ccgttgtcac ctcggcaatg ttgcgcacct gggccgtcag gttactggcc atcgaattca
     2761 cgctgtccgt gagatccttc cacacgccgc tcacatcccg cacctgcgcc tggccgccta
     2821 atttgccgtc ggtgccgact tcgcgcgcca cccgcgtgac ctcggccgcg aaactccgta
     2881 actggtccac catggtattg atggtgtcct tgagctgcag aatttccccg cgcacgtcgg
     2941 ccgtgatttt tttcgagaga tcgccgttgg ccacggctgt cgtcacctcg gcgatgttgc
     3001 gaacctgatt cgtcagattg ctggccatgg agttcacact atccgtgaga tccttccacg
     3061 tcccggccac ccccggcacc acggcctgtc ccccgagttt gccttcggtg ccgacttccc
     3121 gtgcgactct ggtcacctcg gccgcgaagc cgcgcaactg gtcgaccatc gtgttgatgg
     3181 cttctttgag ttgcaggatt tcgccgcgca catcagcggt gattttcttc gaaaggtctc
     3241 cattggcgac ggcggtcgtc acatcggcaa tgttgcgcac ctgggccgtc aaatttccgg
     3301 ccatgaggtt gacgctttcc gtcaggtcct tccagacgcc gctgacatcg cgcacttggg
     3361 cctggccgcc taacttgcca tcggtgccga cttcgcgcgc gacccgtgtg acctccgccg
     3421 cgaaactacg taactgatcc accatcgtat tgatcgtatc tttgagctgc aggatttcgc
     3481 cgcgcacgtc tacggtgatt tttttagaca gatcaccatt cgcgacggcc accgtcacgt
     3541 cggcaatgtt ccgcacctgg ttcgtgagat tgctggccat ggaattcacg ctgtcggtga
     3601 gatccttcca ggtaccggcc acgccgggca ccaccgcctg cccaccgagt ttgccgtccg
     3661 tccccacttc acgcgccaca cgggtcactt ccgctgcgaa actgcgcaac tggtccacca
     3721 tggtattgat cgtgtctttg agctgaagga tttcgccgcg cacgtcggcg gtgattttct
     3781 tggataggtc gccgttcgcg acagcgatgg tgacctccgc gatgttccgt acctggttgg
     3841 tgaggttgct ggccatggag ttgacgttgt ccgtcaagtc cttccaggtt ccggccacac
     3901 cgggaaccac agcttgtccg cccagcttgc cctccgtacc gacctctcgc gcgacccgag
     3961 tgacttcggc cgcaaaggca tccagctgac cgaccatact gttcaccgtt ttggcggtgc
     4021 tcaggaattc gccccgcagc ggatgtccct ctgcttccag ggccacggat tgagtcaggt
     4081 ctcctttggc gaccgccccg atgacacgcg ccatttctgt ggtcggccgg accaggtcgt
     4141 cgatcagacc gttgaccgct tcaatattag ttttccattc tccccgggct tcaggaaccg
     4201 acgcgcgttc cgacaacttt ccttttttgc ccaccgcatg gctgacccgc ttcagctcct
     4261 cagagaacat ggcgttcaat tcaatcaagc cattgatttc atccgcaatc tttccagcca
     4321 tcccatccca ctccgctggc aggcgcacag aaaagtcgcc ctttttgacg gcttggagaa
     4381 tgttgaggac ggccttgtca tggccctcct catagaggac cccggactgt tgtcgcttgc
     4441 cggatcgcga acgcagcttg gtattcattg aatccctccg tccatcactg cagagcagcg
     4501 ccgcggtcga gaagacgacc cacgggttag aatcactgta gtgcgaaaca ctataaaggg
     4561 cgggattatc cgcaaggact gggggatacc ctagttccct aggcttggga ttgtcgcaga
     4621 gctttgtagg aagaaatcgg attggagagg agtcgtgagg cggaggatca ggctgaacag
     4681 acggctcgaa tactgggctc acggtgcccg ccgcccaagg tcaggcatgc gggctctccg
     4741 ggtgcgttcg ttgatttacc acatgacaat tgagcgccag cgatgtcctg cgtccgccgt
     4801 cggaatggaa attctggcaa tcccgccggt gaccgtcacc cgagcgtgcc caatataggc
     4861 gtcagtggga atgggaaggt atcgttcgac cgttccgccg gtgaggataa tgccttgctg
     4921 cgcgaattcc acggcgacct gcatggatgt attctccagc accggtcgaa agtctgcata
     4981 gacattaaag ttaccatcgc tttcggacac ttcgatgacg ggttgatgga gagaaaggat
     5041 tgcggtcgcc ccgcagtatg aagcggactg accgagtgaa gtccctaaga cggcacggcc
     5101 tacgtttggt tcctggattg gacgattcaa ttcatttatc atggcggctc ctttatgaat
     5161 ggaactgatg attgccctgt gcttggtacc ttagcgggtt ttcccagacg agttactagg
     5221 aactcccctt gattcagagt cgatgtccgc tagcactttg cctagttgtg acacagctgt
     5281 cggcggctct agagtggcct gaaaaagtgg tgtcgcgctt cccctactct ggaactcagg
     5341 aatatgtata tgccgagtcc tgacgaaaca tccccttcga tccctcaacc cggttttccc
     5401 ttggatttca tgctagccca tctggcagcc atcgtggaat gttccgacga tgccattatt
     5461 tccaaggatc tcaacgggat gatcacgagc tggaaccggg gcgcgcaaca cctgtttggc
     5521 tacacggcct gtgaaatgat cgggcagccg gtgctacgcc tgatccccga ggatcgccag
     5581 gccgaggagc cacgtatttt ggagcggctc cgccggggag aacgtatcga tcactatgaa
     5641 accgtacgga aacgcaagga cgggacctta attgaaatct ctctctccgt ctcgcccatc
     5701 aaggaccgcg agggacggat catcggggca tccaaaatcg cgcgggcgat atcggaacta
     5761 aagcagggcg aacggaattt agcgcatctg gtcgaggcgc ttcctgccgc ggtctatacc
     5821 acggatgctg acggccgcat tacgcggtac aaccaagccg ccgtcgatct ctgggggcag
     5881 cggccttccc tcgagaccgc tcgctggtcc ggatcctggc gccaatactg ggcggatgga
     5941 cgccccatgc caccggaaga atgtcccttg gcgcaatccc ttgccctcaa tcgccccgta
     6001 agcggattgg agaccatcgt cgaacggccg gacggcactc gcctgccggt ggcctctcac
     6061 cccacgccgc tgcgggatgc atccggcgct cctatcggtg gagtggatat cctcgtagat
     6121 ttgaccgagc aaaagcgggc ggaacgggac atgcagaatt ccgccgctga actcgaacgc
     6181 cgcatcgttg aacgaacagg cgagctcctt ctctcgcagg aacgcctgcg cgcattggcc
     6241 tctgacctca cgctgaccga acaacgggaa cgccggcatc tggctaccga acttcacgac
     6301 tatctggcac aacttgtcgt cgccagccgg atcagactcg cacaagtcat tccgaccatt
     6361 cacgatgcca cggcatcggc cgccctcacg aagatcgatg ggatgctcga ccaggcgttg
     6421 acctatacgc gttccctggt cgccgagctc agccctcaca tcctgtatca attcggcttg
     6481 tcacaatccc tggtgtggct gggagaacag atgaagcagc acggccttga ggtggccgtg
     6541 aaaactatgg ctccgtcatt caccctgccg gacgatcaag ccgtgttgtt gtttcagtcg
     6601 gttcgcgaac tgctctttaa tgtcatcaaa catgccaaag tcgaccgcgc cgcgattacc
     6661 ataaacgtgg atgaggaccg tcgagagttg tggatctgcg tggaggatga aggcgccggc
     6721 ttcgatgtga cggacctgag cgtcgcaaaa aatacacgct gtaaattcgg cctgctgagc
     6781 atcagagaac ggatggagct gctcggaggc gagtgcgaag tgtcgtccgt tcccggaagc
     6841 ggcacggtcg ccatccttcg gcttccactg gcatcaggcg ccctcaagca gccgtttccg
     6901 ctggccgccg acacggcaca gaccatcacg ccttctatag acgcctcttc gcgcaacatt
     6961 aacattctgc tcgtcgatga ccatgcgatg gtgcggcagg ggcttcgaag tatcttggac
     7021 gcacatgaca atttgacggt ggtcggtgaa ggagccgacg gtcaggacgc cgttgttatg
     7081 gcgcgctcgc ttcgtcccga tgtcgtcatc atggatgtga atttaccgat catcgacggg
     7141 atcgaggcca ctcgcatcct gacccaggaa catccctcga tcatggtcat cggcatttcg
     7201 gtccgcaatg atccacaagt gcatgacgcc atgacggagg ccggggcggt cgcgtttcta
     7261 ccgaaggaat ccgctgctga ccagctctac gaagtcattc tgcgcgcatt tcccgtccag
     7321 gcctgagtcc gacgtgaggc cgccgaacta ggggatcccc cagtagcgtc ccgcagccga
     7381 cagtcctatg ctgtaagcgg cttgattgaa tggggattgt tcgcccacga aacacccatg
     7441 ccactcaccg ctgttccacc ttgagtcacg cccggagagg ggtccgttgt cgcttgtcga
     7501 aggcggtaag acccggaggc ttgtcattta cacatgactt cggtgctgct gacgctgcaa
     7561 cgtctggtcc cctccgccgc cggactcgcc attggatttc cggtcttcgc ctttctttgt
     7621 tgggcataca acccgacatt cctctacaac ctgtcgccct cggcaggaac ggttaaacca
     7681 tccacgatgg ccgccatatg tttctgcggc ctctccttgt ggctccaggc cgatgaggcc
     7741 gcgatgacgc gagcgaggcg gcgcatggcg caaggctttg ccggcctcgc cggccttctg
     7801 gccgccgtca caatgttgga atatctattg tccctcgacc tgggcgtcga tctgtggctc
     7861 gcctctgttc cggatttggc ggtggactcc catcccggcc gaatggctcc tgccacagcc
     7921 ttcgctcttt tcatgctggg cttggctctg atccagcttg attcgaaaca cagcggccag
     7981 gaccaggcca gtcattatct ggcacttgcg ggaggcacca ttggggccat cgcactggtc
     8041 gggtatctgt acggtgtcca gacgctgtac aaggtcggta catccaatac catttccatc
     8101 tttagcgccg cgctgctcct ggccctcggc ctgggtattc tgagcgcccg ccccacgcgc
     8161 gggtttatgg ccaccttaac cagcgacgaa ctgggggcgg tgatgctgcg gcgcgtcctg
     8221 cccttcgcca ttgccctgcc gattctggcc ggatggatcc gtatcgcggc tcaacggtcg
     8281 ggccgctacg attttaactt cggggtcgcg ctggccgtgt cggccgtcat gttgatcatc
     8341 ctggcctttc tctggttatt ggccgggaat ctcaatcgca gcgacgggca aaagaagcat
     8401 atcctgcaaa tactgcagca acgcgaggcc cggcaccgtc tcgcgctgaa ggccggtcgt
     8461 atgggaacgt tccaccagga tcttgatcgt cacaccctgg tcttttctcc cgaactggaa
     8521 cacatcttcg gtttgcctgc gatgagcttc ggcagtacgt tcgccgcatt ccaggatctg
     8581 gttcatcccg aggaccgggc acatgtgctc aagaccatta actacgcgat tcaacaccgg
     8641 agcgcctacg acctcgaatg ccgcatcctc cggcaggatc ctcccgagga agcctggatc
     8701 gcagtcaccg gacaggtgtt gcctgactcc accggccatc cgaggcaaat caccggggtc
     8761 atgtttgata tcacggaacg caaacactcc gtgaccgctc tccagcagag tgaacagcag
     8821 ctgcgggtca tcactgatgc gctgcccggc cttattgctt ctgtcgattg tgacgagcga
     8881 taccggttcg tcaatgcggg ctatgagcac cagttcggac tgtcgcgtga ccagatcgtg
     8941 gggctttcgg tgaaggatct cctcaaggag gactattcca ccgttcagcc cttcatccgg
     9001 cgcgtgctga gtggtgaacg catatccttt gaaactaccc tcctggatga gcggggtgag
     9061 cagacgctgt tatcgacgta cgtgccggac cgaaactccg aaggcatggt ggcgggattc
     9121 tatgcgctga tcacaaatat cacggagcgc aaacgcaccg aatccgcgct gagagaaagc
     9181 gaagaacgct tcaggcatct ctttgagcag gcgtcggacg ggattgtgac cgcggacatg
     9241 aacggccagt atctcgatgt gaacaatcgc gcctgccaga tgttaggcta tacccgcgaa
     9301 gagctcttcg acctgcgagt ccccgacctg ctggacccgc atgactaccc gcgattgaga
     9361 gcgatcaagg ccgaactgat ccaaggacat cgtcattccg gcgaatggaa attacgccgc
     9421 aaggacgggg gaaccatctc cgtcgagatc agcgcgagat tgcaaccgga ccgccgctgg
     9481 catgccatcg tcagagacat cactgaacgc aaacgggccg atgcgggatt gcgcgaaagt
     9541 gaggcgtatt ttcgcatgct ggccgatgcc actccggtgc tggtctggaa agccgggacg
     9601 gatcggctct gttcctggct caaccggtcc tggttggagt acaccgggcg tttgttggat
     9661 gatgaactgg gaaccggccg gaccgacagc atccatcccg acgaccggga tgaattcaac
     9721 agggtctaca accagcactt ctctcgccaa gagccctttg aactggaata tcgattacgc
     9781 cggcaagacg ggacctacgg atggatcctg gaccgcggcg ttccgctgct tagcgccgcc
     9841 ggggtgttta gtggctatct cggcgcggcc ctcgatatca cggaccggaa gttagcggaa
     9901 gaacagctgc aacaatggac cgtcgaactg gagaagcgcg tggacgagcg cacgcaagca
     9961 ctcgtgcatt cgcaagcgcg tctccgtgcg ctggtatccg atctcagcgc cacggaagag
    10021 caggagcgtc gccggctcgc cacggagtta catgactatc tcgctcagtt gctggtcgtc
    10081 ggccggatga aactcagcca agcgagaccg caggtccgga atcccaaaac ggaacaactg
    10141 ttgagtgaag cggacgacat gctcacgcaa tcgctcaact acacacgatc cctcgtcgct
    10201 gaattgagcc cgcagatcct gtatcaattc ggtttgcctg ccgccctcaa atggctggcg
    10261 ggacagatga aatcacacgg gctttcagtg tccatccaat gcggcatcga tcagctcacg
    10321 ctcgctgaag aacgcgcggt cattttatat cagagtgtcc gggagcttct gttcaacgtg
    10381 gcaaaacatg ctggaaccgg cgaggccatg atcacgctgg accagagtcc gaccaatcag
    10441 gtgctgatta ctgtggcgga caacgggcgc ggattcaatc cagccattct tgtagacacc
    10501 gagggccatc atcctggacg gttcggactc tttaacgtgc aagaacgcat cgaagcgatc
    10561 ggcggaacac tgagtctcaa atcttctgaa ggctgcggaa cgacggtcac actgattgtg
    10621 cccctgaagc cctttccaga atcggctgtc gagtctgacc tccccgtcga cggccatgtc
    10681 ccggatgtgc tcaggacccc gtctcaacga ttacgcattc tgctggtcga tgaccatgcc
    10741 atggtgcgtc aaggattgcg gagtgtattg gaaagttata ccgatctgga ggtggtgggg
    10801 gaagccggcg atggagggac tgccatcagt atcgcctccg ccttaaaacc ggatgtggtc
    10861 gtcatggata tcaatatgcc gaacatcgac ggcatagagg cgactcgcca tatcctcagc
    10921 gagcatcccg atgtcgtggt gatcggcctc tcggtccaaa acgaacggca tatcgaagaa
    10981 gccatgttga aggccggggc cgcggtcttt gtcaccaaag aacgggccgc cggccaactc
    11041 tacgaagcca ttgtgagcac cgtgcgaacc agacgatgag cagttcgcac gggtcacaca
    11101 gctggcgggc gtcggcccat caccatgccg atcacggcca aaatcagaaa gatcacgaac
    11161 aggacatacg cgatatgcgt ggcggttcca gccactccgg tgacgcccag cacacctgca
    11221 atcagcccga tcactaaaaa agtcacagcc cagctcaaca tgatcgcacc tcatctatag
    11281 gtgaacccat actcccttat ctatcgggag ccccgctcga atggtacgcg tgctgcgtac
    11341 cacacccttt atgcccgcag acacaacttc cggtcggcgc tgcggcattt cgacaggcat
    11401 cggaacaaaa ctcacggcct ttttcggcct cacaagcaca ggcaggatgc gcgcatgatt
    11461 tttttcgtat ggttgcctcc gccattacct cgtcctttcc ggcggccgac tccgccttcc
    11521 ttctcgagcc tcttcccttt gctgatgtta gaaccacagg tgaataccca tgccgatcca
    11581 ctccacccgt tgagtaaaca attgtccgtc cgggctcgga ccggagtaat actcgcccag
    11641 gacctgcaac ttccgatcgc cgatccgggc attttcaaac tgcaagccgg ccataatgga
    11701 ctgaccggtc gtccaatgcg ttctcgcatg ggtttgaaaa tcggcgtacg ccacaggcct
    11761 cacttttccc ccgaagaaga gccacggact cttgagctcg accccgcctt gagtcgtttc
    11821 ccgccccaac gtgctcgggt cttttctcac aatcgttccg acgccgccgt acacccgcaa
    11881 ccaggtcgtc agatcgtatg acatcttgag atcgatctcc tcatagctga ggttgatccg
    11941 gacgacctgg ggattattca gtaaaaattc gtctcctaaa tgtgaactct gatgccgaat
    12001 acgaatgaac ccagagaatc tatcggcccg atagctggcc acaatgccga aggtgtagtc
    12061 ggcattgatc aaatcgatcg agcgcttttc cgtatcgaat acgccgaaca caccggcttg
    12121 aattcccagt tcccattcgc cctgaaaagg agcggcatcc cggtacaccg agaaggattc
    12181 gccgaaggca ctggcaaatt cccggccgcc tgatgaaaga gaatggtagg aggcgccgaa
    12241 atgcggccat cgtaaatccg cgtgaaacgg gtccacgagc aatccgcgcg gaagaaattt
    12301 cgattccgcg gtcggtgtcg tcgcacggac cacgcccggc cccgccgctc cttccggcgc
    12361 agaccccgtg tgtacctcag cgctaacaac cccgggaatt gccttgagag ccgtgacgat
    12421 cttcgccggg tcctcagccg ccaatcgctt ggcatacacc gccacccgcc cctgttcgac
    12481 ctgcaccacc gctccagaga gatggaactc atgttccagc aggccggccg cgtatccggc
    12541 gatatactcg tcggacgcgg ccatcgccat tcccgcgaat cccgccatca cgcccaggag
    12601 aaagagggcc atcccaatag gcgatgtgcg gctcctagtc ccctctttcg gacacctgtg
    12661 ccacaacctg ttccacctca cagctccgtc cgtctcagcc tagaaatgga agttgacacc
    12721 gaccgtcacc atgtggccgt tgtcctggaa ctttttgtcg acgatgtttt ggtcccggga
    12781 ctcgattttt tccagccaga tgtaccggta cgtactgtcg atggatacat gcttgttaaa
    12841 gaaaaattgg agaccgccgc cggcgtgagc gccaaaccgg ttttgcgtat catcgaagcc
    12901 gcccggcccc ttcacggtcg tgtaatacca cccgccgcca cctaacaaga atggcgccag
    12961 tctggtggtg cccagtggat aaatcagagc ggagacttga acggggtagg tatggacgcg
    13021 cgtatcaccg atgtcgttgc ggcgatagtc tgccgagcct tcaaatgcca ggtaccgcca
    13081 gggatgcaat cgaacctgcc cacccccgaa ccatcggctt gagccgtcct tcggatcaat
    13141 gtatgtggcg cgaccaccga tggagagcag cccgatgtcc atctgctcaa acaacccttt
    13201 atcgtccgcc gcccttgctg gggacggcac gaccactccg cccgcgatca aaaacgatgc
    13261 acacaggacc aacgctgcgc tcaagacccc ttgtctcatt gtcgatctcc tctgtaaatg
    13321 gcaatgtggc ctagttgact tcgctaggat tgggtcctct tctccccatg gctctcaaac
    13381 cattcatcaa cccagcgttt cacttcttcc cgccgatcgc cataccgctc ctggatcttg
    13441 ccttccagcg tatcgatgcg cccctcgatg agcatcaagt cgtcatcggt gaactcagcc
    13501 cacttctgtt tcaattcacc catgaattgt ttccacattc ctgccaattg atcctgattg
    13561 acggccaaga tcagggtgcc ctgtgtgcca cgtaacctgt gttgttcgcc cgcatgtccc
    13621 gccgccgtca tcatcagaat ccccgcgagg gcgacgattg acagcctcca gtgcccgagc
    13681 ctcatcgtgt ctctccttcg aagccgatgg caaggcgcac cggcgtgtca cctgccggta
    13741 cgcctggtgc ccctcaacgg tctattttcg cctgaccgct ttgcgcgtcg acatagactt
    13801 tctgttcttt gttgttcgag tcgatgattt cgacttcata gaccgtgcgg ccatcttgtt
    13861 ttccgatctc agcctctacg gctttacccg gaacaagctt caaggcgtgt ttcacggcat
    13921 cttccagggt gaccgtggcc gtcgccgcta actgcttgtt cgtttcaaac agagcccagg
    13981 ccgggctggc tatgacaccg gacaacaatg cgatggcaat cattttcttc atagggccga
    14041 ctccttccgc gtcaggttga gctttgtacg tatcctcata tgtgttcagc gcgggggctg
    14101 agtctcccga tgctgagttc cctgctgcgc ttgcccttgg cggctgtacc aatcatccgc
    14161 ccagcgcatg acttcttcct tcttatcccc ataccgctcc tgaatgcggc cgaggaattt
    14221 gtcgtaatct ccttcgacct gcttcaggtc atcatcggtc aattttcccc actgtttttt
    14281 gacttcccct ttgaactgga cccatttccc tttgaattga tctgtattca tcgtgatcct
    14341 ccatagtgat gtatcattgc cgcggacgct tgcgcccctg aggaagcggc gtccccgcga
    14401 ctcctctgtc gggcggcctc tttcagtacc cggtgggacg gagatcgaaa agcaagtccg
    14461 gtttttccac ctcggtacaa caccacggta ttctcctcgg cgttgtcgcc gagggtgacg
    14521 acgatcttcg tccgcactcc gtggtctttc tgatgtggtt tcataggcac ctcccgacgg
    14581 ttgtccatct ttgttatatc tccgaatagg gaaatggttg actggacaaa gccctagttt
    14641 taaaaggccc tcgcccctga caggtctacg agtacgtaat agtgcgcgca cgtctagaac
    14701 gggggcatag cctcgccgga gaggcagtag tcgaagggag agcagcgagt gacggataag
    14761 acttacgaat cgagcacgga gtttaagcgg ctgaggatgg cgaccgatcg agcctgggtc
    14821 gtgtagggct cccctccctt aaaagtcgga gtcggagtcg gagccgggtc cggcttccct
    14881 ggctccgccg cacccggcgt gagccgccaa gtggcggatc attcagatga gggtaacaga
    14941 aactcgaccg gttcatgatg cgcattcgag agcaccagaa atgtatcatc cacaattgcg
    15001 ttgccatcgg catgcagcca cacaatgtcc ataatggagg ccggggcgcc cctccggcag
    15061 gtagacatgc caggtttgat tggtccgttc ttcgagacga atccgatgcg attccctcgt
    15121 cgcatccggt ccatcaaaga ggcatagttc caccgacgtg gtattttcag aaaacagggc
    15181 aaaattcacc ccttccccat cccacgtggc tcccagcgga tagggtcggc ccggccagac
    15241 tttcatatca tctccatccg aaacggactg tgaatcgaga cgtcacagta gcgctcgacg
    15301 tcatcacttc agaagactga ccaggtcctc ggcatgttct tcttctttca tcagaatggt
    15361 ttccaacagc cttctcgtcg tgggatcatc actgccgaca aatgcgatca tgtcgcgata
    15421 actctcgatc gcaatccgtt ccgcaatgag gtcttccttg atcatttctt ccaggtcttc
    15481 gccctccaca tactcggagt ggctacggga agataacccg tccggcgaga gattcggttc
    15541 cccgcctaat tgaacgatcc gttccgccag ttcatccgca tgggcctgtt cctcacccgc
    15601 atgcgccagg aactccgcct tgacactttc cgcgttcatc ccctgcgcca taaaataatg
    15661 ccgcctgtac cgcaaaacac agacgatttc cgtggccaac gcttcattca agagtttgat
    15721 aaccgtgtcg cggtcggcct tgtaatccgc ggtcaacgcg ccttcttcga tatgttgccg
    15781 ggcacgttcc ctgatggact gcacatcctt aatcattgac gcttgaggct tctcagtttt
    15841 catgtcgact cctttcaacg taaaggcacg gtcacgtggt ggtcagcgcg agaagtctgt
    15901 gcgcacatgg ggccaggccg attccagtcc caattccgtc atcaaaccct gctcatccgt
    15961 ccgttgcgtc accgttcggg cctgggtccc gaccacgagt gcacaggcag cgatcgaaat
    16021 gagcaatccc atatacttac cgaactgatt gcctgacaga gacaccggca tcatgacgtc
    16081 tcctcctcta ctgacaacag ctgtgctcac actagaagag aggcccagag ggacgtacta
    16141 ggcagaaccc ttggcaacac aggggattcc cctcggccac ggacgagcga agtcaggaag
    16201 gaggaacata aattgacaac acccccgcca ggcggccttg gcgatccaga accggcatcc
    16261 aatcgacctc cgacaggcgc atgagcgctt gtgcatccgt gagcagatcg tcctcctggc
    16321 aatagggaac ctgctcgctc atgatgtctc tgaccgtcaa tgcggtggta gggggccggg
    16381 aactccgatg caatgcgaca tcccgatcgg tcaccatgcc caccaaacgc gtgccttcat
    16441 agaccacgat caccggaacg ttcatcgccg ccatcaacga caccgcctct tcatgactcg
    16501 tgtccggcga cacgacggtc aaggctgaag acatcacgtg tctcaccttt cggacttccc
    16561 ccggcaacac tcccaaatcc tcatcaattc tggtttccag atacagacgc cgacgcggac
    16621 gtgtaaagcc ggcctcggca atggtacgag gaacgttcga tttgctggat gtgctggtca
    16681 ttggtgcaag attttcaaca attaacaatt tcagacagct tgaggacgag cttcgtggac
    16741 ggtaattcga agccgcccat actgtacggg cttgtcgggg tcccgagtgt aatgactttt
    16801 atcctccccc acggagatca tgctgagagg aagcgtaaga tgctgtttat aatgtggaaa
    16861 tgccgtctcg agcagcaacg tcaccgtttg cccatcgcac tcaatcactt cggcattcag
    16921 gtcgtgctcg ttttcgaaat cgacggtcac gcgctcctcc ggattgatcc actgccgaat
    16981 gcttgccgcc ttctctgaag attccatgcg ccgcctccgt gtcgccgcat gccgacggcc
    17041 gtcacccgcg accgtctttc gccaacgaca tcaacacttc tcgcatgcat tcgctgatgc
    17101 caccactggc aataactcta ggtcctcagc cagctgcgga atcggcggat tgaccggttg
    17161 cggtggaatg ggtggaggaa acggctccgg tggaaatgga ttcggaccag gatccggatt
    17221 cggattcggt tcaggaaacg gcgcgggtcc tgggttcatc tgcgggaaca gattcgagtg
    17281 gcgacaattc atagaaggcc tttcattcaa tgcggaatag cgacggatga caatccggcc
    17341 tgaagccggt cttcaaccac gccccatccg atattgctaa aaaaagagtc gatatactgt
    17401 ttccgctcac tgggctggta atccaagaga aacgcgtgct cccacacatc catcacgagg
    17461 atgggtagaa agcccgccac attcccatgc tcgtgcagag acacccaatg gttcgacacg
    17521 agcccccttg ccggatcgac attacagatc gcccatccca cacctcgcat catgcccaca
    17581 ctgcaaaagt cggccttcca tcgctcatag ctgccaaagg tacgttcaac ggccctgtga
    17641 aaggcggagc cgttcggcgg ctccgctccc cctccacgcc gaagattgcc aaaataatat
    17701 tcgtgcaaca ccatcccgtt gaactcgaat cccagcctgc gcgtcagttc cgagtaggcc
    17761 ggcatttgtt cgtgatcgac gtgtccttgt tgaatgaatt cagacaattg ctcgcgcaat
    17821 tcgtttgcgg cttttacata gccctcatac agcgcgaaat gaacgcgcaa cgtctcatcg
    17881 gagatacccg acaatccgaa caggtcaaac gctttggctt ggtacggttg ggtgacggcc
    17941 atgttgagcc cctttcatcg tgcttaagat ggacatactt caccataggc ccccaccttg
    18001 cctttcccaa ctaggcgatg ccctggcata ccatggccta cgcagggggc tttcctaggc
    18061 gtcatctttc ataaattacg gcagtatgaa ctgaatggac ccccgaagaa tttaccgggg
    18121 aagagaccgt gcaaagacta gcgcagacct gctaaggtga agggaccctc gaaacgacga
    18181 gagtgtcacc gcggaggagc tggtaaagta gtcccaccga gagaggaagg agcaccgtgg
    18241 ccagagcacg catcgtcatt gccgatgacc atagtctggt gttggaggct taccgacaat
    18301 tgctggagcc ggatttcgat gtggtaggta cggcttcaaa cggccaggaa ctgctgaaca
    18361 tcgcgccggc cctgaatccg gacattatcc tgctcgacat ttcgatgccg accatgaacg
    18421 ggttggaggt cacgaaacaa ctgcgtgccg ccataccaca cgccaagatc atcttcgtga
    18481 ccatgatgag tgagccgttt tatatttcgc aggcctttca gatgggcgcg tcagcctatg
    18541 tgttgaaaca atccgcttcc acggaattgt tgtccgcgct gaacgccgcc ctcaagaatc
    18601 agcgttacat ctcgccgcag ctctcccttg aggtgcagga tgccatcgaa acgccctggg
    18661 tgaaaccgga aggattttcg tccaagttga cgcctcgcca gcaggaggtg ctgcagttgc
    18721 tgacgaaggg catgtcgaca aaagagatcg ccacgaccat gcatgtgtcc acgaaggccg
    18781 tggaattcca caaaggcaac atcacgcgcc gcctcggcat ccgcacgact gcagaactca
    18841 cgcgcttcgc cttatcgcaa ggcctcacga agctgagcga tcaacatccc tgacagatga
    18901 cgttacggtt gagagccggg aacggtaggc tgttgcggca tggcgatgag cccgatggca
    18961 atcgcatgtt tggtcagctc ggcggtgcta tgaatgccga gctgtttcat gatgcgggtt
    19021 ttgtgaaact ccaccgtctt gatggacaca ttgagcgtcg aggcgatttc cttggtggac
    19081 tggccttccg cgatcaactg cagcacttcc cgctgccggc cactgagcga gtcattcgac
    19141 ggaggcgccc cggcgggagc cggcgcaacc gggtggagcg cctgggcaac cagattttcc
    19201 gccacgctcg gtgacacgta cagacggccc tttaagactt ccttaatcgc aaataccaat
    19261 tcgtctgcca ctgactgctt caacacataa ccggagaccc cggcgcgaaa ggcttccgtc
    19321 acgaagtact gctcgctgtg catcgtgagg acgaggagct tcacttcggg aactgatttc
    19381 ttgatttgcc ggcaggcatc gaggccgttc aagagcggga gtgcgatatc cacgagcgca
    19441 atatccggct tctctttttc aacggcccgg acgagggccc gtccgtctgc ggctcgaccg
    19501 cacaattgaa aatcgtgttc cagcagtttt tctacacctt ctgcaacgag tgtatgatcg
    19561 tcggctatga ggactcgtgg tttcatggat atgctccggg ctagtggaca agccgagtag
    19621 gaactgctgt ggaatcctac cactctcttc agatgaatac gagtggttcg tcggtcacaa
    19681 ttccttcgac cagaaaaaaa tgatgccatg cccgcccttg gtgggcggcg cgccgcctgg
    19741 gtcccgatag atcccgaagt tatacgtgta attgagttcc acctgcgatt tccacggggc
    19801 ccccgtcacc aatccgccgc ccaaggccgg catggaatcc gtaatacttt tcactgccgt
    19861 gttcgacgta aacaccggac gctccaccaa tccccaggtc gcctcgacgt aggggtacag
    19921 aaagaataag gcctcatagc gatattgcaa gttggccacg gcatagcggg tcggaaataa
    19981 ttcgttgaag gcgacaccat ggatcatcgg cagcgaaatg gcttcccact cataccccgt
    20041 cggccggcca gggaggcgga acgctgagaa tcgatccagg tccttcccga tccccgcatg
    20101 aatactgctt aacagacggt gcttgtcgct ctcgatgaat ggcagtcccg tagccagtaa
    20161 ggcgtaggcg ctggcttgaa tgtacgtctg ttcctttttg aaatcctgag tattgaacgg
    20221 ggcgcctccc cattgatccc acttcgcccg atgaccatgc accacatcgc cgcccaaggt
    20281 gaatccctcg tgtggcagct ccatcaggtt gcgcttcagg gcatcggcgc gaatccggaa
    20341 atgaatccgg ccttcatacg tgtccttcgg cacgccgtag tccgcggagg tgtgacccgt
    20401 gcccttaaac cagcgatatc cggcttcata cgtgagcgaa atgttgaccg cgctgtcctg
    20461 acgaaaggga tggaccggca gtcgataccc cagcccggcg ccggcaaacg cataactcca
    20521 ctccaactcg gtgcctcgct gacgttgccc ttgcacatac tccgagcggc cgaacggcag
    20581 gatgaaatta tcccaggtga acaagagcga ccagttcgga tagtcgcgca acccgatcgt
    20641 atagtccaca tcgttgacga cccccgaaaa ggtcccgcgg agccgccggt tgtcatcgtc
    20701 ccaattcctc cagacatata acgcgccgaa gggcagtact tcctgttgcg tgggcccgtt
    20761 gggaatggcc tgaataccga aactgatggc ggtgacactg cgccggtccc ggggcggcac
    20821 ataaatttct tccccgaaca gggtggttcg aaacggctca cccgcaatcg gggtgggttc
    20881 ctcggccagc gcgaagtcct gcccgagccc aaacagatcg tcaccgattg cccctacaga
    20941 gaacagacat actatgctgc aactcacacg gaaacaccat tcagagagag ttcgacccat
    21001 cgattctatg gctcctgaca tcgcacgtgg gattccttga cagccgatgt cctcttatat
    21061 gtcagccgtg atacacccgg cccctagtga aacccctggc agagggggtg gaatagccga
    21121 gttctttttc gtcgcaggtc gcgcaataca tgggaaattt ttgtcgcagc ccccttttct
    21181 cgccaacctc tcaaacaagg aatattccca gtgttctcct gtgtggacca aagataggtt
    21241 cacgacaatg gaacgtacct atcgaactca gccacattgc ttcaatggga cgtctgcgca
    21301 tgttcctcgc tggcgatgct gtctcgccgc cgccggattg ttcctcctga cgtcgaccac
    21361 actgttcgcg aacccgattg aagtcatcta cccggaaggc gttagcgaag gatttgttac
    21421 gctcaagacc ttggacggca aaaagctcgc cgatggagaa ctgagccagg taacgaccgg
    21481 tgccgatcga ctggccagcc ggctgacctt tcgttttgcc gacggctcgc tctatgacga
    21541 aaccgtcacg ttttcccaaa agaaacatct caccatgttg agttaccagt tgactcagcg
    21601 agggccggcc ttccccgagc ccctcgtgat ttcgctcaat ggcgaaacgg gacagtatca
    21661 agtccggcaa cgcgaaaaga cgccggatga aaagctgatc accgggcgcc tggaccttcc
    21721 gaaggatgtc tacaacggcc tcaccattac cgtcctgaaa aatcttcgcg gacaaaccgg
    21781 cgccatcgtt cacatgctgg tgtttaaccc tgaacccaag ctctacgaag tcgaattggc
    21841 tcgagtcgat gaggaggaca cgcgcaacac caccaggaaa gagaccaagg ccacagcggt
    21901 gcattacagc ctcaaacccc gcttgggatg gtttacggca gcgctggccc ggcttctcgg
    21961 acgaactccg cccgactacc acttctggct gatcaagaaa gacgcccccg ccttcgtgcg
    22021 gtttgaaggc agcctctacg caggcggtcc aagttggaga atcgaacagg tttcgccgcg
    22081 cgtcaaacaa gcccgggttc ccgagcccta gtgacctgtc aggggaggcg ttgtaacgag
    22141 gcatccaacg ggacaagggc cgctgagttc cggccaatgg ccagggcctc caccgcccgc
    22201 ccgaatcgat tgatcgtccc gtttcccctc accctcacgt gctccccgac atggaaggag
    22261 cgccggagtg cgggactggc atcgggtgga aaccgaacct gcgtctcatc cgacagcaac
    22321 atgccttgaa tcgtgtgttt cagcggatgg tagaagaagg cacgaatcgt tcccgccgca
    22381 ctcatttccg tcatcgacag cgtgtgctcc tgctcctgca tgggcaggtc caggcggagc
    22441 ggaacggtga acgtcgttcc cgtcgtcacg ttgatcacgg catccgcctg aaccagccgt
    22501 tcatcgggca tgagccggcc gtagacccgt acggcgttgc ctggtgcgaa cgcccggacg
    22561 agctgatccg ctgcccgcga ggtgacgtac agatgagtcc cgtcggcaag gaacaatcct
    22621 tccacctctc ctcgtggatc cagaataaaa cggtccactg ttccctctgc cgcaagggcg
    22681 ccatgaacct ggtcatgctg cgcggctgct acggaaagca ccggttcggc cgaccagacc
    22741 aggaatggtc cagcttctcc acacacgatg ccacccaaca tgatgccgat cattacaatg
    22801 gccctgccgt tcgattgacg cattctccct ttttccctca acccgagcgt tcaactccgc
    22861 tgccggcgct cggcagggct ttccatgcga gaaaatccat aagccgaatc aatgagcgac
    22921 acgtgggaaa aggcctgcgg aaaatttccc accagccgtt tgttcttcaa atcgtattcc
    22981 tctgacagca atccgaggtc gttactcaac ccgatcaacc gttcgtacaa ccggcgcgct
    23041 tcctccacgc gtccagagag caacagattg tccaccagcc agaacgagca gggcaggaac
    23101 atcccttctt cacccggcaa gccatccaac ttcccggtgg gctgataccg catgaccagt
    23161 ccatccaccg tcagctcgcg ttcgatggcg tgcaacgtcc cctgcacgcg aggatcgaat
    23221 gccgggagaa atccgacgag cggaatcatc aataaactgc cgtccaagga tgttcccccg
    23281 taatattgca cgaacgtccc ccgattcgaa tcgtacccct ctcggcacac ctgttcgtga
    23341 atcgtctcac gcaaggctcg ccatcgctcg agcggtccat cgacatgaca tcgctcgatg
    23401 gccttcaccg cccgatccac tgcgacccag gccatcacct tggaatgggt gaaatgccgg
    23461 cgcgggccgc gcacttccca aatgccttcg tcggggcgat cccaggcggt ctcaagaaat
    23521 tccatgatgg catgttggac gcgccaagca tcttcgctgg ccgccagccc caactccctg
    23581 gcctggtgca gggtgtccat catttcgccg taaacatcca actgaaactg ctgggaggcc
    23641 gcattgccga tacgcacagg ggctgattgc tcgtacccgg gcaaccagtt caactccagt
    23701 tccgtgagtc tccgttctcc cctgatgcca tacatgatct gcaggtccga aggtttccct
    23761 gccaccgcac gcaaaagcca ctcgcgccag gccttggctt cgctgtggta gccagccgac
    23821 agcaaggcat acaacgtgaa ggtcgcatcc cgaatccagc agtagcggta atcccaatta
    23881 cgtacaccac cgagcaattc cgggagcgaa gtggtcggag ccgcgacaat gccgcccgtc
    23941 ggggcatagg tcagcgcttt caatgtgatc agtgaacgga ccacatgatt ccgccaggat
    24001 ccctgatagg tgcagcgttg ggaccatttc ttccaccaga gctcggtctg agataacgca
    24061 cgttccgtga tgagcggtct tgggggagag tcgtgggagg cccgccacgt cagagtgaag
    24121 ggaatctcct gcccttcggt gacggtgaag tcggcgacgg tggaaaatcc cacgccctgt
    24181 aattccagtt cggtttcaag atacaccgcg tcgggaccgg ccaccgcctt caggaagcgg
    24241 cgctgatggc tcacccaggg tacgattgat ccgtaatcga atcggagggt caggtccatc
    24301 ttcatgcgca cggtaccctt gactcccacg acaacacgta ccacattgat gtcgcggtca
    24361 cggggtggca tgaaatcgat caacatcgct gtgcccgttg gtgtttcgaa gagcgtttcc
    24421 agcaccaggg tgtcaccccg ataccgtcga cgaatagttg tgttatcttc gtggggcgta
    24481 atgagccaac gtccatgctc aggcgtaccg agcagcgccg cgaagcaggc cggtgaatca
    24541 aagcgcggaa gacagagcca gtcgagagac ccctggcggg taatcagcgc tgctgtgtgg
    24601 gtatctccga tcagcgcata gtcttcgatt tttgccgtcg cgttcatagg cctctcgcgt
    24661 aggtgcggtg acgtgattga tgattcgttt taaactgtac aggcgggcac tcgcctaaac
    24721 aacccctaac atctcaggag gacaacatga gaaaggttct ggcgaaaaaa acgcagccgc
    24781 gcaaaaaaac ctcttctgcg aaaaagcgca ccgtcaagcg ggacatcgaa ccagctgcgc
    24841 atgtgatcga aagaaaaacg aagaagaagc cggccacatc cgccaaggcc aaaaagacca
    24901 cgctgacaaa gaagaagacc tctaagacaa ccaggaaacg atctcccggt tccagccgca
    24961 acgccaaaag cgtcggtcgg gctgtgggga aagtcatcgg ccgagccatc ggaacagtcg
    25021 aacgggcgct taccctcgtc aggcctaaca gcaatacacc gaagaaacaa tagatagacg
    25081 ggaaaaggaa cagagtcgct agggggacgc ctagtacgga tgttgtgggg aaacctctac
    25141 actgaatcca agcgaacgag ggacgaggac ctcgtgatgc gtggaggtgg acccatggca
    25201 tttcaagtgg tttcgaaact ggtgagcacg acgctgttcg tggctctggc actgcctgca
    25261 gcgctggccg ccgcaaatcc cgctcccgag tcgggccagc ctcagccgcc ctcgccccag
    25321 caaacgccgc cgaccgcccc gccgtcgcgc atcgatccgg gcatccaaaa ggctcccgac
    25381 acggttccca atcccaaatc catcgtgccg ccacctgtgg tcgatcccaa gatggcgatc
    25441 gatcctgaac gaccgggtgg gccggcacat cccaagccgc cgtcgccagc agacaagccg
    25501 cctatgccgc cgcgatgaca tcatacggtc cattctcctg aatgcgaggt cggcacgcag
    25561 gatggaccgt tcatctcatt gcggattgat ccggcggtct ttccaataga tcagtcgagc
    25621 acccggctta aatgtcacgt aataccatat ccactcgaac atcactctcg ctcgattgcg
    25681 aaagccgatg agaaagaaga tatggacaaa gcaccaggcc agccaagcca caaccccgga
    25741 gagtgagatc gggccgaatt gtgcgaccgc cttggcacgt ccgatggtcg ccagtattcc
    25801 acgatcccga tatcgaaacg ctgagcgttg gccgtcggga atacaacggg caatgatccc
    25861 cgccacgtag cggccttcct gcatggcgac ggccgccaat cccggcaacg gcttctgccg
    25921 ggccgaaaga cagtgcgctg catcgccgat cacaaacacc cagggatcct ctttgagact
    25981 gagatcgggg cccactatca cgcgccctga ggaatctaat ggaacgtcta gcgaagcgag
    26041 aatgggtgat gccacattgc ccgcagccca gatcacatgg gcgctgctga tgaattctga
    26101 tccggccatc acgcccttcg acgtcacatc gtgaacgcgg cagttcagca gcacagttac
    26161 gcccaggctt tcaagtgagg cttgcgccct gctcgataag gcgggaggaa acgcttccag
    26221 aatacgcggt cccccttcga tgagcagaat tcgagaagcc gcttggtgca gcaccggaaa
    26281 atccggcgtc atcgcctttc gcccgatctc cgccagcgcc cctgccaact ccacccccgt
    26341 cgggccgccc cccacgatca cgaaggtcag ttcatcacgc gcctcagggg tgcccttcag
    26401 gcgctccgcc ttctcaaatg ccatgagcat ccgttcgcga atctctaatg catccggcag
    26461 ggtctttaaa ccaggggcat cctgctccca tgtattgtgg ccaaaatacg agtgcctggc
    26521 gccgggggag agaatcagac tgctgtaaga gaccggctca ctattccgga gctcgatgcg
    26581 acgggcggaa cgatcaacgg cccgcacttc atccatcatg atccggacgt tctgttgggc
    26641 ccgaaggagc gttcgaaggg gccaggcgat gtcagccggt gacagggctg ccgtcgcaac
    26701 ttggtagagc aacggttgga acacgtgatg attcattcgg tcgatgagga tgacctcccc
    26761 cttcaagtgg tgcagcgcgc gcgccgctgc caatcctccg aatcccccac cgactatgac
    26821 gaccggattt cggctctgct ggttcactcg cgcttctcca tcacgcttac ggtgaaaggc
    26881 atcacagcag gcgtctcgct ggacgcatca tctctgcacg agcacaacgg agccactagg
    26941 gagccgccta gttctggaaa ggcacgcgct ctcgctatga tccatctcgc aggagtggct
    27001 cttcatcacc acacattctt gtcggaaaca aacgccagct acctgccttt cacatcacac
    27061 ccaacattca cacacattta ttgtgccggg aaaaggagcc aggtatgaag atcgctcagg
    27121 tcgctccctt atgggaaagt gttccgccgg tgctctacgg cgggacggaa cgcatcgtct
    27181 cattcatcac ggaggagctg gtccgacaag gccacgaggt cacgctcttt gccagcggag
    27241 attccacgac aagagcccga ctgatgccga tgtgtggcga agcgctccgc ccctcaaaag
    27301 tcgtcatgaa ttatgaagcc cctttaacag ccatgatcga aaaggtattc gggtcagcac
    27361 ccgaatatga cctcattcat tcacatcttg aattcattcc tttcccgctg gccaaacgat
    27421 gccgaacgcc gatgctcacg accttgcatg cccgtctcga tcagccggag ctcatcccgg
    27481 tgttccggaa atttgccgac cttccgctgg tctccgtctc ggaggcgcaa cgtgaaccgc
    27541 ttccctgggc gaactggcag gcgacgattc atcccggtat accgcattcc ctctatacgc
    27601 ctcagtacaa ccagggacag tatctcgtgt tcctcgggcg cgtcgcgcct gagaagggac
    27661 tggaccgggc tattgaaatc gcgaagcgcg ttgagatgcc gatacgcatc ggtgccaaaa
    27721 tcgacgcgca gcatgcggaa tactataagt cggtcatcga gccgctcttg gaccatccac
    27781 tggttgagtt tgtgggagaa gtgacggacc ttgaaaagga tgatttactg ggagatgcct
    27841 atgcgctgct cgctccctat gcgtggcctg aaccgttcgg cctggccatc atcgaagcgt
    27901 tggcctgcgg cacaccggtc atcggatcgc ggcgcggcgc catccctgaa atcattgaac
    27961 atggcgtgac cggctttgta tgcgacacac tcgacgagat gacccaagcc atcaggcatg
    28021 tgtcgctgct cgaacgcacc cgttgccggc aagcatttga gacgcgattt accgcggaac
    28081 gaatggcgca ggaatatgtg acagtctacg ggcagatcct gggacttccc gacaaggctc
    28141 ctcaaccttc atccgacctg gcttccggat tgcctgctgc cggccagatc taattccacc
    28201 ttcacgcacg aagggcaggt actctgttga gcacctgccc ttctcgaacc acctacttct
    28261 tctacttatc gcttactgct gggattgcca ccttcgaatc ccggagcttt ccctgaaggc
    28321 agcccgctgg tgccgctcgg tccgccgcca cccacagact cttcacccat ggagccggtt
    28381 gcgtcaggcc ccttttgtcc agggacgccg gcgctgccag gaacggtcgg ggcttcccgc
    28441 acctgtccca tcttatcttt gtattcttgc aggtcgggag acttgtcttt gctgctgctc
    28501 ataggcagcg cattttgaat ctcctctttt ttcaaggtca attggagctt gtcgcctttg
    28561 gttttaaatt gactccacct gatgggttgt ggcctcttgg attcattgga gacgaagacg
    28621 acatattcaa tgtctccggt cttttcatct ttcatgacct gctggatctt gccgatctct
    28681 tctccgttgg tgccatagac agaggcattg agatatttgc tgtctttcat ctcaacgagc
    28741 ttcccctgtc ggacgggcgt atcagcatat tcttccggga caccctgttt cccgcccgtc
    28801 agatctgttt tcttgtcgaa tgaaggggat tccttgggcg tgctggtgcc cgcgccctta
    28861 cccatggtgg aatccggcgg tggcgcgcct gatccggttg agacctgact gaaggccggc
    28921 gtgccggtca tcaacgccaa cgcaatcgtt cctgcataca tggccattcg tcgattcatg
    28981 tggattctcc tttgtatgag atgtcgtggt ggacgcccct actgatttgg ttttaccaat
    29041 agggcttgta gccgtaatag gtatggagcc gctcggccca ggcggtgtcg gccatgtccg
    29101 gccagcgatc cttatcgaat ccttccgcct gctccaaacg ttcccgcggc acattgagaa
    29161 tgaagaaatc tcctcccggg gagatcgtga gcgcccccca cggcagagcg aacagcttgt
    29221 cccccaatcc taaaaacccg ccgaaggaca gtacggcata ggcaatccgt cctttttcga
    29281 ggtcaatcat gagcgaatga atctcgccca gatcttcgcc tgccgcgttt tgaaccgcgg
    29341 tgccttcgat cgttgacgct gtcaataatc gacgcccgat atgtgtggcc atcattttcc
    29401 tcctctaatg ttaggaatca ctgcatatga gtgttcatgc taatggcgct gtgcccttgt
    29461 ccgtcgtccg tcgaactcat ccctctttct tgtagtgtta acccccgagc ctcactcggg
    29521 cagctaggaa ggaccctaga aaataggaag gagaaatgac ctgcaggaaa gcctatcgct
    29581 gcgttcagaa gcaccgttcc agcagggcca cagggcaatc acgtagaacc tggttgatcg
    29641 ggagaacttg tcggccctct tccgtgaccg tttcgagacg ttggcccgta aggagattcc
    29701 tgtagagcga gccgggcttc cacgagggaa ccgtcaggcg agtgtcctgc cacgtatcgg
    29761 cggccccacc cgaatcggat tggatcacct ccgccgtgag gcgagggatg acggtgacaa
    29821 tggcctgttc gtgatgcaag cgggcgaagg cgcagatatt cgcctcacgg acgccgtcac
    29881 attcgagcgg cacatagtcg ccgtcgagat agagtgccgc atgttcacgc cgatgacgaa
    29941 gacctgcttg cagcagatag agcttgatac gaccatcttc ccaggactcc aggaggcggc
    30001 ggaccagtgc caaccggttg acgtcatcct ggccggcatg tttctgacag tcttgcagga
    30061 tcgcggcacg ctgatcgaag tcgactggcc tgcgattatc aggatccacg agactgaatt
    30121 cccacaactc tgtgccctgg taacaatccg gaatccctgg tgcagtgatt ttgaccaata
    30181 gctgcgccaa tgaattgttc atgccgcaac gggccacgaa cgcctgaaac gggagaaact
    30241 cctcgaggaa cgggttggaa acagaccggt ccaggatagc ctgcacaaat ctcttcatgc
    30301 cctcctcgta atcttcacga ggattaatcc agccggtgtg cactttcgct tcacggatgg
    30361 ctttgatcat gtactgttca atccgctttt tgaactcctc gtactgaggt tgatccatcg
    30421 gagtcgaggg ccaggccccg agcagcgttt gatacagcag atactcctcg ttccgatcgg
    30481 gcgcgacagt ctcgtccact ttgactcgaa agcgtctatt atgtttcgcc cagctggcca
    30541 gggcagctct ccagcgttcc ggaatctccg acaggacatt gatccttgag cgaacgtcct
    30601 cgcctcgttt ggtgtcatgt gtcgacgtag ccaacagggc atgaggccaa tgcgcacggc
    30661 gttcccgcag cgccttgtga aaggcgtcga cagaaagtcc atagtgagcc ggttcaccac
    30721 cgacttcatt gagcgacacg aggcggttgt aaatatagaa cgcggtgtcc tcgatgcctt
    30781 ttgccgtcac agggctcgtg gtctgttgga acttcgtcac aaatcgcacc tgatccggtc
    30841 ctgcgagttt gatccgatca tccaggcgct tcaggagaag gtctcgcaca aagtcgaaga
    30901 cctggctgtt caaggtggga ttccggcgtt tcgccctgtt cacggccatc atgatgtagg
    30961 tgcggtcccg ctccagcaca tctttttgat ccgccgtgat gtaggagcga tagacaggaa
    31021 aacaggcgat cagttccgtg atggcgtggg tcaaactatt caaagtgaaa tcccgatatt
    31081 gccggtcttt ttccgaaagc agattcaatt ggtgtcccag cacgttcagc tcgctggaca
    31141 tcgaggcccg catgatcaac tttttggtga gatacaccag gtcgtcgtac acaatccgct
    31201 gaccgacgaa acgctgatac aaggcatcca tggaccgttc cttcgccgac tggacgaaga
    31261 ggccattgac gaggttcaga aagtcatagc cggtcgttcc ggagaccggc caggtcaccg
    31321 gaagcgattc gcctttgccg aggatctttt cgaccacgac gaacaacgag gccggctccc
    31381 ccgaggcggc cggctcgagt tctcgggccg cccactcctg caattggacc aagtaatgtt
    31441 ccgggtcata gagcccgtcg acatggtcga ttcgcaggcc cgtggccaca ccgctcttta
    31501 acagcctgaa caccaactgg tgagattcct ggaagacgcg tgtttcttcc gtgcggatcg
    31561 cggccaattc gttgatatca aaaaatcgcc ggtaattgat ttcctcggaa gccacgcgcc
    31621 aggacgcgag acgataactc tgctcgtcga gtaacgcatc cagccggtcg aaactggccg
    31681 aatctccttt cacaccgttg tacgtatcaa cggtggccga cagatgcacg cgaatggtct
    31741 cactctcctg gagtaacgct gccaggcggc gcctgatcat gtgcgcttca cgataccgtt
    31801 cagcgatgcg tttcgggtca cgctctttcc tcgccggaag attgcgtaag gcggtcagaa
    31861 tactgagcag ttcctgaacg tgctcatcct gctcccccac ccgcgccgtc aactcttcca
    31921 ggcggaagga taggatccct tcccaggatt ggggcgcgac aggaaaccgg tgctggaaat
    31981 acgtgacgat gaagccgcca ttctcgtaga ccagtcgtat atcctggttc tccaataccg
    32041 cgccgtactg ttcgccgaga atgggcagca gcaccttatc ttcaagctcg cgcttcaacg
    32101 gcgaccaatc gatgtcgaac gctgtggcat agcgagatcc cgggccatgc tcgagaacgt
    32161 cccaccacca ccggttctcc gtggagcgga tccccatgtg attgggcacc acgtccaata
    32221 agaggcccat atcgtattgt ttgagcgccg ctgtgaacgc agcgaagtcc tctttggttc
    32281 ccagttcagg attgaggcat tcaggatcca cgaggtcgta gccatgcata ctgcccggca
    32341 cagccttcaa gatagacgac acatagcaat cggtaatgcc gagcgcgtag agatagggaa
    32401 caatgcggcc ggcgtcacga aaggtaaacg tatggttgag ctgaagacgg taggtcgcga
    32461 tgggaatgcg cggcatacgt atcagagcgc gtgccgccgt tcaataggaa ggcagtcgtc
    32521 gcttctgctc ctctgttgcc gcctgaggtt tggggatgac cagcactccc gattccgccc
    32581 attctgaggg cgcgtccatc tcctccccgc gctcttgccc gcggggtccg agatcgacat
    32641 tggccggaat ggtattgtgc cgatcgacga ccacgcgctg cagcttcgcg ccggcgccaa
    32701 tgtgcgtgtg atcgaaaata atagagtctt cgatataggc gccggattcg attcgcacgt
    32761 ggcggccgat gatcgaccgt ctgatgtccg cctcgattgc ccgtgtgcct tcaccgatca
    32821 aagcgtgatc gacataacaa ttcacgagac ttgccggagg accgtaggac ggttccgttc
    32881 taatcggcca ttcccgattc cccagatcac agggcggtgt atcgccgagc aggtccatat
    32941 tggcttgcca ataggcctga atggtgccca cgtcccgcca ataggccggt tcctcgtgat
    33001 acccgacgcc cggcacttca ttatcgagga agttgtacgc catgacccgg tccgttttga
    33061 gacggcgcgg aagaatgtcg cggccgaagt catgcgatcc gccctcctgc ttggcatctt
    33121 cctccagggc ctggatcaat acatcggcat tgaagaggta attccccatg gacgaaaggg
    33181 catgcgccgg gtcgcccggc atggatttgg gcaccggggg cttttcgtcg aaccccacca
    33241 ccagactcgt gcgatcaatc tccacgatcc cgaatccctg tgcggcatgc actggcaccg
    33301 ggagtgtcgc gaccgataca tccgcttccc ggtcgagatg aaactgcacc atctgccgaa
    33361 tatccattcg gtaaatatgg tctgcgccga atacggcgac gatgtcagga gcaaaatcac
    33421 ggatcaggtt gaggttttga aagaccgcat ctgcggtgcc ttcataccat cctgctccgg
    33481 agttcatttg aggagggacg acggtgacaa attgcctctc tccatctcca atccgccatg
    33541 ccttccggag gtgctcgatc agagattgcg atcggtactg caccatcacg tgcatgccca
    33601 gaatgccgga gttgtaaaaa ttgctcagaa cgaagtcgat aatccgatag gcaccgccga
    33661 acggaacggc cggtttgctt cgcgcttcgg ttaacggcat gaggcgcgtt ccttttcccc
    33721 ctgccaggat catggcaaga acgcgaggct gactgatccg tccatgtttc tccataacgc
    33781 tcctcggtag gcaggatgat tgcagcgggc acggccacta tcaccttaca aaaaatgtcg
    33841 ccgatcgcgt actggacaaa tccctagcgc actctgcgca aagccaaccg caatcagcaa
    33901 tgtcaggagt gaaatgattc ctcgctgcag gaagaagaga acggatcggg atacgccgtg
    33961 tttgaatcgg cggaagttct ctacgggggc gctcgaaatg ggctacaact taccgaccaa
    34021 atcaagacct ggtgtcagcg tgggctgccc gggttgccag ttggccggac aggcttcccc
    34081 ctcgccttca cgcactcgaa tggcggcctg aagtttgcgc aaggtttctc cgatatatcg
    34141 gccgatactg ttgtcatgta cttcgtacgc gcgcagcacg ccatcgggat cgatgaggaa
    34201 ggttcctcgc agggccacac cctcctcctc aagatagacg ccaaactccc ggctcaacgc
    34261 tccggtcgag tccgcaatca atggaaattc aacagtgcgt accatcggcg aactgtcgtg
    34321 ccaggcctta tgcacataca cggaatcggt gctgacgccg cacacttccg caccgagtgt
    34381 gacgaattca ggatacagtc gcgccagttc ggcaagctcg gtcgggcaca cgaacgtgaa
    34441 gtctccaggg taaaacatga ggaccaacca tttgcctcgc aattcttcca acacgagagt
    34501 tcgtatctcc ccctggtgat aggcttgcac ggtcgatggc gaaatttctc gtccaatagc
    34561 gatcatgatg tcctttcctc gaaccgtgtt tccggtggtc cttcgtgcgg acctacaacg
    34621 cccgtaaaaa tgctaccagg gcagccttct catcgctgtt caactgcagc cccgccacga
    34681 cattaaagaa ctccacgcta tcctccagcg tcaggagcct cccgtcgtga aaatatggcg
    34741 gcgaatcttt gatccctcgc aacgcgaagg tcttgatggg accatccgct tcggcgccga
    34801 agcgctctaa gaagagatcg tgcatcatgt gatcggtata ggctggaggt tggtgacaga
    34861 ctgcgcaacg ggctttgcca aagaacagat cctctcctgc aatttcctgc cggtcggcgc
    34921 gggatcgatc caaccgtccg gtcatgggat ccagctttgg tgccggtgga aagtcgatca
    34981 tgttttggat ctgtgccatg tgggccactt gcaagcgatc gatgatgctg atgcccttct
    35041 tggcggcacg aatgtgatcg ccgttgaaat aggctgtacg ctgttcgaat tctgtaaaat
    35101 cttccacaga gcggagactg cgcttggagc catgtatctg ctgattgaac attcctcgca
    35161 ggctcaccgt atcgagacgc agacggtcac gctgcgggcg ggtatcggga ttcaaatgaa
    35221 attggcccgt cgtatgaaaa ttcacgtgac agtctaagca agcgacaccg gcgctaggct
    35281 tgggcgattt gcgatctgcg gtcaggttga attcctcctg cggaaattgc gtgaccagca
    35341 ttctgaggcc atccaattgc acgggcgtga tcaacccacg aaacaggcga tcaaaattct
    35401 ccacgctcaa gacttcgccc tgcgacacat cacctaattc aggatgggtg gtaagaaaaa
    35461 tcggcggcgg aaactccggc agaaagcaag caggcagatc gaaatcgaca tcgaaccgct
    35521 ccagcctagg gaactgatgg atctgttcct cgggaaacac catgcctccc acctcgtgct
    35581 tcacgtgagg caatcgcatg aaaccggcgg gaaacgcctt ttgctttcgg atttcttccg
    35641 gttccatctg ggacagggat tcccacgtga ggccattctt gagttggacg gtggggccaa
    35701 tcggttgtgg ctttcctttt gtcatgcgta cggtggaatg tgttttacac tccagtcgat
    35761 aacggtcctg taagagtctc gcctgttggg ccatgacctt gggtttctct tcctgatcct
    35821 tcttcatggc ttcctgagcc aggcgagcgg atgattgccc gggaggtccg ccaaagaggt
    35881 cgtacgagaa atccacacct tcgaatccct tttccttggt cttctcaatg gccggattca
    35941 ctgtgtgccg cggttctttt ccgtcccgat cggcatagac atatgccaca gacatagcca
    36001 gcaccactcc aaccgacacc aggtgcgata cagcttttcc cgccgtccgt gttgtttttc
    36061 gtctcacagt gtcacctcgt cataggggcc aaatcgccgc atacgctcgc ggttctgttt
    36121 gaaacaatct gcacaggacc ggaacggttg tcctactagg cagacccctg ggccggagcc
    36181 gttcttccct atgactcagt gaaaccaggg agtctcctag tgctccgccg gtcatctgat
    36241 ttctaggatg ggagtcgata ccaaacagaa cagatcttgc gtggaaagga ggcctactat
    36301 gaattgtcat cgatgcagca acttgatgtt tcccgttgcg cttcaggatt ggggcggagg
    36361 actcatgaat caggatgtcg cggcctggcg ctgtttcgcc tgcggagaaa ttgtggatca
    36421 gctgattgcg cagaatcgta cccgcggtgg cgaagatgcg gaagagtggc gccgaggggg
    36481 cgcacgccgg cgggtcaacg gaatcggact cttacgttag acgacaatac ctcccattta
    36541 ttccgggcgc cggtgagcaa catcggcgcc ctgcttatcc ttcctctccc gccggctcat
    36601 ccaggcgcag tcaatcatgg actattcggg gtgggatcat agccctcaaa cggctgccgt
    36661 cccaccacca gcaccaccgc aaccagcgct agagcgatga gcagataaaa cccgaagcga
    36721 aacgcttcgg tatagggtgt gctgaacgtt ccgaacgcat agagacctgt gagaatcatg
    36781 cctatcagca cgacggcaac cagtagggtc gtcattgcag cacctccagc gtaagtggtg
    36841 agtttcccct cagccgacgc ttgcatcggc ggatcatcaa ccggtggatc ttggtgcggt
    36901 ggaggatcgt ccggtggttc tttctccgga gggtgctgtg gccctggttc cttcaccggc
    36961 ggttttgacc cggtctgcgt catagggtca cttccagcaa acacagcaat acccataccc
    37021 catgcctccc cctgagtctg agcgatcatt gcagatttcc ttatcacccc gagcccggca
    37081 cgaccgcaat cgcggatggc ctgtcctcca aaggacagat tgtctccccc ggccattgca
    37141 cacacacctt attgctgaca cccaaaacac cagaaacctc gcctccactg cattttttga
    37201 ccagcgtccg tttcaagcac ggcaacggtc cgtcttttgc taactacggc atcatcggcc
    37261 gacctgcagt gaacgacata cgaaggagtc accatgaccg tacacatgaa tcgctttctg
    37321 ccacatcagg gccttcattt ggcaaccgct gtcggtattt ccatgatgct cagcggggta
    37381 ccggttgcca tgacgtccgc ccatgccgcc gaggaaacca aaacaggtga tacctcacag
    37441 cttcgtgagg atgcacaaac gttactcaaa ggaaatcgca ctgtgttggc aacagtactt
    37501 gccgtcacct cggatcagat caaagtcgac atcggtgaag ttcaaccgcg ttttctcccg
    37561 ctgaagcagg cacaacagaa agggttcccg aaagtatccg aaggcgatga cctcatcgtc
    37621 gtcctgaacg aacaaaatct tctggtcgac tatcatcctc tagacggagg cacgagcgcc
    37681 cacacgatca tccgtgggga actttcgcag acccttccga ccgggcatga aacggctgtc
    37741 ataaagtcgg gaggcaaaga acaatcgttc aacatccgct ctcaggcgcg gagtaaagtc
    37801 gcggccatcc cccgcggagc cacggcggtt tttctgatcg acgagacgaa tcagattgcc
    37861 gacgtcagcc tgtcccgcca acaggcggcc caactcgcgg gagcgcattc tcaaccgatt
    37921 aaaggccagc atcaacaggt tgaaggaacc gtcacgtctc ccttgcagtc gaatcacatt
    37981 acgattcgca ctcccggcgg cacggataag ccatacgaag ttagagacat cctccagtca
    38041 aaaatcgcga cactccacaa aggagatgcg gtcgtgctgc tgatcgatgg cgacaataaa
    38101 gtcattgacg tggccattcc gcccaaaggg aaataacgcg cacggcgctg tggtctggga
    38161 caagtccgtc acgcgactcc ataaccggct gcgaggccgt aatggcgaag tttccgcagc
    38221 agtgttttcc gatgaatacc aagaatcgtg gcggatcgtc ccagatcccg cgcatgggaa
    38281 tccaacactt gaagaatgtg gtttcgctcg agatcttcga gggtgaccca cccttgcgcg
    38341 cgtgccaacc cttcaggctg cgcgtccttg accgccggag gaaggtcttc ggggcagatg
    38401 acggaatagg ggctcaacgt gacagctcgc tcgatcgcgt gttccagttc ccggacgttg
    38461 ccgggccacc agtagcggcg gagcagggcc agcgcctcag cggacaattc cgtgacgggt
    38521 ggcattttca tcgacccgta caggcgcaaa aagcgtttgg ccagcaatgg taggtcgtca
    38581 aggcgctctc gcaatggcgg gatgtcgatc gtcacgacat tcattcggta atagagatcc
    38641 tctcggaatg tgcccgcccg tacgagaggc tccagcggaa gcttagaggc cgcaatgatt
    38701 cggacatcta acgccgtcgt tgcggtactt ccgacacggc gaatttcctt ctcctggagg
    38761 acacgcagca acttgccttg taatgccggc gacaggtcgg ccacctcgtc gaggaaacag
    38821 gttccggaat gggcttgctc cagcagcccc tttcgggaag agatcgcccc ggtgaaggag
    38881 ccacgttcgt gcccgaacag ctctgactcc agcaagctgt cggccaacgc tcctccatca
    38941 acggtgacga acggcccgga gcttcgaggt ccgctcgcat ggatggcccg ggcgatcagt
    39001 tccttcccgg tgccgctttc gccctgtagc aacacggagc tatccgtttg agccacccgg
    39061 gcgatcgctt tgtagacctg caccatggcg gggctgctgc cgacaaggct ggcgaagggg
    39121 gacgtgtcgt caggagcggc ttcgcccgat gcagcctgct cggcccgcat atgagtgtgt
    39181 tcgaccgcac gtcgggcgac agaacggact tcctcggccg tgaacggttt actcatatag
    39241 tcaaaggcgc cggctttgag tccttctacc gctgtccgta gcgaaccatg agcggtcatg
    39301 agcacgatcg gggtggtggg acagagtccg cgcaattgac gcaggcaggt cagctcctcc
    39361 gtttcaggag gaaggtcagt gagaatgaga tcgacgggga tccgttcgag gtagccgccg
    39421 gcgtccttcg ggtcgcgaac ggcggaaacc tcatatccgt cgacggacaa catgtctcgt
    39481 aaaacagtcg cagcgcctac gttgctatcc acgatgagaa tacgggcctg tgtcatggtg
    39541 gttatcatcc tagcgaggtg atggtccaat gcacatgaga gtcatagcct acgctcgcgg
    39601 acaatcgccc gacacctgga tgaaaccctg gtctttgggt gtctttatga tgcgcggcaa
    39661 cgctcgttct gacgccgaac acaccttctc tacccccgct cagccccatc aggagaagat
    39721 gtgtgcactt gctcgcacag taccatggtc catcctccta accgtcctct gctgtatggt
    39781 gatgttttct atggtgatag tcccccttct ctgtctttgc ccagccgttc caaaagccag
    39841 aacccattcc gccggctccc atccccggcc cttcccctaa accgctgccg cccgcgccaa
    39901 tccctgctcc cgcgccgaag cccattcccc ccgctccacc gaggtgacgc acagttccct
    39961 ttcctagaga gtccagcgtc ttgcgcgaca gaaacagggg gttctcctcg gaccgatgga
    40021 gtaacccgcc gtgatacgca tgactagaga ctcactcctt ccaccgttca tgaagggagc
    40081 ggtcatgaag agatggctgg cttgctgcgc atcagtgatc gtgacggcta tctggttccc
    40141 ctgttcgtcc ggggcactcg agttcacggc cgatcgggtg acacacaccg atcgcggatt
    40201 tcaccgagcg cggattttct atcatgacgg catgtggcgg ctggagcaca acgagcgagg
    40261 gccggtgagc atcacgatcg tcagactgga tcgaaatcag gtgtggcatc tgttgccggt
    40321 gacccatcat tacaaaaccg tctcgtacga tcgcgattat gcccttcacc tggcgacgac
    40381 gcttgatcat gaaatctcgc gggaaacgat cggcgtccag atcttagacg gccatccgac
    40441 tgtcttgtat gaggtcctga ccatcacgcc gggaggcgga agagaaagtt attaccaatg
    40501 gattgcgaca gacatcaatt tcccgctgaa actggccaag aaaaatggcg actggatggt
    40561 ggagtatcgt cacgtcaagt tcgggcctat ctcggacgtg ttttttgagc tgccacgcca
    40621 ctacgcgcct atggacgacg atcagcacac cgcgagttcg ccggagccag taaggaggat
    40681 gagcccatga cgacaaggac ctcccgacat cagatgaccg gggcaagaga ccatatcgtg
    40741 atcggactgc tgccgaacat gggcgcggtg cgagaagcgc tggaagctct gcgggctcgt
    40801 ggcatctccg atgatcagat cgggctcgcg atgcgccaag ctgaagaacg gttatccgac
    40861 gaggagagtc cctcgcctac agcacaggac gcgacgaccg ggatggtcgg cggaggcctt
    40921 atcggcggac tggcaggtct gttgaccacg accggcgtgg ttgccattcc cggtctggca
    40981 ccattgctgg ccggcggctc actcatcggg ctgctgggcg caacgggcgc atccatcgtg
    41041 gcagctagcg gactcggcgc agtcgccgga ggactcgttg gcgcactgat cagtatcaac
    41101 gtgcctgaaa cggccgccaa acattatgcg gatgcggtcc acgagggaca gattctcatc
    41161 agcgtgaaga ccgacggcga ccctgcccag gttgaagagc tcctcgcttc tttgggagcc
    41221 accacggacc ggcaatcgcc ctagcgctgg tcgctgatct ttctagggaa accaccagct
    41281 tcgccgtcat gggacttcga ccatgatgtc ctcagcacgc actgaggaaa cctttccaac
    41341 ttttacaggg agcactgccc aatcggcact atggctaagc aacaagcatc ccgtacgaag
    41401 agcaacacac ctgctgcgca gaaagttgtc tctcagaacg gatcggccga gccaccggtt
    41461 ccacaccacg aacccatcaa aacgctcgtc gtcgatatcg ggggcacagg cattaaatcc
    41521 atgatcgtca atgaagtcgg agagcccatt ggggaacggt tgcggctccc gactccgaaa
    41581 cgaaaaactc cgcccagcgt gctgaagacc attcatcgtc tcgccaaact gtccgggcgt
    41641 ttccatcggg tcagcgtcgg attccccggc accatcagaa acggcgtcat ccttgacgcg
    41701 gtgaacctcg acccttcctg gaagcacttc aatctcatcg ccgcgctcgg caaaaccctg
    41761 cgcaagaagc ccgttcgagc ggccaacgat gctgacgtgc aggggtatgg cgcgatttcc
    41821 ggaaagggag ttgagctggt tttaactttg ggaacgggcg tcgggtcctc cctgttcatc
    41881 gatggccgcc tcgtcccgaa tttggaagtc ggaaagaatc ggctgcgagg ctccgagctc
    41941 gaacgcatcg gcaaaaaatt gtggaacaat cgcttgctga aggtcatcgc caagcttgaa
    42001 aaaatgtttc actacgaccg tctctacatc ggtggtggca atgccgtgca ggtggatatc
    42061 gggcgggtcc ctggcaatgt caccgtcgtc tcgaacctga atggactgct gggtggaatc
    42121 gccttgtggg aagaagccgc ccacttcgct gcgagcagac aggaactggc gaataacaac
    42181 gccaaccatt ctgccccgcc taagccggca gctgaacgcg ccgcaccgcg tgggcgctga
    42241 gcagattgct ccagcgagcc ccgcgactga gacaagttgt ccttgctcag acaatcggtc
    42301 cgtaccctgt atcgacctgc gttgggcatc agtcgtgaag atctttcaaa cagcgctgcc
    42361 agaaagcaca gtccacacgt ttcataagcc catgagaaga ccctgctgtg gtcccgcatt
    42421 tgcaccggtg ttgtgttgaa gaatgtcata caggcatccg tttggtctct taacaagaat
    42481 gatttggagg atcacatggc acacatgcgc gggggagtca gaacagcgcc atctgagcgc
    42541 cgtcacaagt cagagcagga caggaacggc ggcggccgga tggaggcaag gccgcatggc
    42601 cgacaagatg agacggacca gaacgtgggt gacaaggaac ggttgatctc cggcctcgtc
    42661 gggggcggcc tgctgctaca cagcctgaga ggtccgtttt ccggcctgag cgcgctcaaa
    42721 gccctcctcg gcctcgcact cgtgcagcgc tccgtcaccg gtcactgtgc cgggtatcac
    42781 atgctcggga tgaacacgca tgaccagacg gatacatcat cgataggacg ctccaaagtg
    42841 catagcgacc gggccattaa aattgagcgc tccatcacga tccaacgatc tgccaaggag
    42901 ctctacgcct tctggcggca actcgacaat cttcccacca tcatgagtca ggtccgcacg
    42961 gtcgaacctc tggatgatcg caggtcacat tgggtcatca acaccctgcc cggcgctcct
    43021 accgtggaat gggatgcgga aatcatcaat gaggtcgaaa acgagcgcat cggatggaaa
    43081 acgctcgatg gcgcaacggt cgaacacgcg gggtcggttc ggttcactcc gttgaacgat
    43141 gaacgccaga cccgggtaac cgtcacattg caatatgatc cgcctgccgg ggccatcggt
    43201 gccgccatcg cagatctgtt tggacaggag ccagggcaga agatcgcccg cgatctcgag
    43261 cgtttcaaag aagcgatgga gtcacacacc accgtctctc agtgagcaga caggagtgcg
    43321 cggttcgatt cctattgcgc atgcgttcgg tctgccggag tgaaaggggg aagtatgaat
    43381 atgtggcgag gcctcacggt cgcagtgatg gtgatgggag cgactgtcat ttctggagtg
    43441 ccgggtggag ccgctcaaaa ggaatccatg gagaagacgc cgaaggtgga agacgacaca
    43501 tcggacaaat ctgcggggaa ggcgtccaaa gataaggtca tcaagaaacg gcggtcatca
    43561 ggcaagagca atgccgaaga cacaaccgat gccaaatcac aacccaagtc tcaagagtcg
    43621 cgtgagggga cacccggcac gaccttgatg ttcaggtccg acggcgcagg aaactccggc
    43681 gcagcgggca aatagacagg atcagcggag aacttttgca tccataatct tgaaggaggc
    43741 acaccatgcc gaaacagaac aggcacatcc ggctgttcgc cgccatgctc ggactaggaa
    43801 tcatgagcgc cacaggggtc tatgcggacc aggcacgtga acagagagaa gcgggcctgc
    43861 aggggcagag cgatgggcga gtccacaatg cagatatcac cggcggcttc tatgacgacc
    43921 gctacaaact cgacgactgg tactacgatt tttatgacag tccgggatat tcccgtgctg
    43981 attccacgtc cgtcatccaa gcctccaacg agaatacggc caccatggca gatgccgctc
    44041 atccatcctt gcggcatcat cggccctacc gcactgacca gaatgtcccg gccacgccct
    44101 atgccggaga tccctggttc tatgcacagc gggaccccat gtacggcata ccggaaacca
    44161 gctcggatgc gtacggtgga aacgtcatca aaggcacgat caaggcggcc aaacaagtcc
    44221 gcaaccggac aaccggtgat caaaataccg tggtattgct caccactccg gatcgccggc
    44281 aagtcaccgc tgaccttggg tcttcacgac gcaccatgga tctcgcactg acgaaaggtg
    44341 attcgctcgt cgtggccggt ccatgggagg atgtgggtcc ttactccgtg cttatggcgc
    44401 agcagatcag gaccgaagcc aagcgcgtca ccctgaaccg tccgatcggg gccgcccgcg
    44461 gagacaggac cgtggaaggt cgtattcagc aatttcgaga cattcgaatg aatcgcagcg
    44521 gggaactcca tcgcgcagcg gctgtgcaaa ccccggatgg gcggatggca cttgtggacc
    44581 ttgggccgga taatcaggac cggacaccct tgcgagctgc cgccggcgac cggatggtgg
    44641 cccaggggcc ggtggttcag gtgggcaact accctgtcct ctgggccaac cgcgtggcca
    44701 tcaatgacgg catgccggtt gacgtgacgc gtacgactgc gccgactgac ttcgtaccgg
    44761 caaccgggaa caggcaggaa aactgtctcg gtgccggctg cgacaaccag ccgttaaatc
    44821 agggccagcc cggcaaccgg aacagcaacg cgatggatgg caccactcgc tgatccgggg
    44881 gactccctcc tgcgcaggga agggggaccc attggatcct ccttccccat tttcacgccg
    44941 ctcgtgctgc tggtgtcgat catcagatag gggccaggcc cggccctcgg gtctcgaaac
    45001 gttgtggggt acggggggat gtgccgatgc ggggcgcgca cggcgagttg tcgttgttga
    45061 ttaacaacaa gggtgtcgcg accacactgt ttacaaacga atcgtgatgc tgcttcgccc
    45121 ggaaacgggg tccaagctcg tcaccatctc tctcaccttg cgctccacca ccggctcgat
    45181 tcgctcacga agaatccgtt cacaggaaag aaacatcgcc tcgtgaacct gccgtaacaa
    45241 tgagcgtcct tccggtgatt cggccaatcg cctctcagcc ggtaccgatc cctgcctcgt
    45301 caacgtcact tcgatttcat cctgagacag atgcacctgg acattggcat agttggatcg
    45361 catgaactca gtgtgaaagt tcaggatcgt catcatgagc gcatactcga gatcggcttt
    45421 attggtgctt ctttgtgcca tgctctgctc cccgatagtc tgaagacgaa tcgcaacctg
    45481 ccgatgccgc ttacgtgcgg aggctgtcaa accggacagt gaccactcgc ttcacactgt
    45541 accatgaaat cgcatcccgg ccgatgcacg gtgaaacgac acgcgtggga catgccggcc
    45601 tatgaagtcg ccagacatga tgaagcctcg gggcacatgg ggccccgagg cttccgtgag
    45661 gctaataggc cttgctgaag gccggttcac catcatgagt ccagagcttt tgcgctgcgg
    45721 accaccacca gcccttctta gtcaagaccg ccaggaatgt atcgacgtca gcatcggtca
    45781 catcccctgt cgccatgaac cgacaacgat accagttcac catcatcaga tcgggactga
    45841 cgaaccccgg ccagaccttg gttccccgat tggagatgaa ctcgcattta aacggcccga
    45901 actcgccgtc cggaaatttc ggaatgcctt cttcggtgac gatgtacatg tccacaccga
    45961 cgagcttgat aactttcttc ttccgcgtcg ctttcgctgc ttcagaaaac gttgttgcca
    46021 tgggcgcttc ccctttcttt atcaatggcg ggattctcag gctttcccct gcatcttgtc
    46081 gacgatggct tgagcatatt cgtcggtggt ggcggttccg cctacgtcgt aggtgacatg
    46141 tttgccttca tggaggaccg cgaacatggc tttttcgata cgatcagccg ccgcagtctc
    46201 cttcaaccag cgcagcatca tgatgccgga caccaacacc gccgaagggt tcaccttttt
    46261 catccccgca tacttcggcg ctgacccgtg caccgcctcg aagatcgaac agttgtcccc
    46321 gatattggcg cccggcgcga aacccaaccc tcccaccagc cccgcgcaga gatccgtcag
    46381 aatatccccg tacaagtttg gcagtaccag acagtcgaac tgagcgggat tcctcacgag
    46441 ctgcatgcag cagttgtcta cgatgacgtc cccggtttcg atttcaggat acttcttcgc
    46501 ggcctcgcga aacgcatcca gaaacagccc gtccgtcatt ttcataatgt tggctttgtg
    46561 cacacagtac accttcttcc gaccattggc tctcgcccac tgaaacgcaa agtcggcaat
    46621 gcggtaagag cctggccagg tgatgacctt caggcattgc gccacttcgt cggacaccat
    46681 atgctcgatg gccgcatagg aatcttccgt gttttcccgg aagttaatga tgtcgatctt
    46741 gtcccagggg cgcttcaaca ccggaatcag cttagccggc cggacattgg caaacaggtc
    46801 gaacacctta cgcaacgtca cgttcgcgct tttgtgcccc gtcccgacgg gcgtcgtcgt
    46861 cgggccttta agcgccacct tgtttttggc aatgttcttg atggtcttat ccggaagcaa
    46921 ggtgccgtac ttctccaaac atcccaatcc gatctcttcg tattcccatt tgatatcgac
    46981 accgctcgcg tcaatcacca gtcgcaccgc ttcgcagatt tcagggccgg tcccttctcc
    47041 cggaagcatc gtgactacat gttgtgccat cagagaacct ccttgcgtca ccagggggta
    47101 accggaccat ccgttccccc gctcgcacag acatcatgtg caaaggcgat tccacggcgt
    47161 agtcttgccc gtgcggcggt gtctgccgca tttttcagta caattcccgt ctccggcgtc
    47221 cgtgcaggtc ggtcccttgg tatgggaacg gtgcgatcgt gcacagacac acactgtacg
    47281 ctgtgtgcct gtgcatctgt gctcagcagg ataagcggac actacggttg gacaagtgcc
    47341 tgggcgggaa acgtttttgc cagaggccgg cagtaaccgg ccagttgggg agatccagtc
    47401 acggccacca ccccatgggg cccggcagcc tggaccgcac gcctgaatgc ggcttccgta
    47461 ctgtctacca cctcagcggc gaccgaagag caggttcgcc attgttcggc aatcgcgtcg
    47521 ggcggcacgg ccctatcttg tggaccgccg gtcacgatga gccggtcggc tcccgctccg
    47581 gcaagagcgc gcaacacctg ttcccattgt gcatcccgcg ccagggatac gagcaagaca
    47641 ctgcggcggc cctcgaaggt cgtgcggaga atagtcgcga gccgcattgc cgccggggcg
    47701 ttgtgcgcgc catccagaag caccgcgggc gtgccggaca gcacttcaca gcaggctggc
    47761 cattccgtct tctcgaatac ccggccgatc tcgtccggat cgatgtccgg aagcagtcct
    47821 cgcttgcgta acacgtcata agccatgagg gcatgagcgg cattggcggc catgaatgcc
    47881 gcaggcgacc gtagtcgcag ctgtggatgc gtggacgcgc cgacccttac cgtacaaagt
    47941 cccgcatagc cgtcacggat gaactcggtg acttcataat cctgcccgct gagtagcacg
    48001 ggtgccttga gcgccgcggc tcgagacagg accacggccc gcggcccctc cggcatcggg
    48061 ccgcacagca ccggcgtaaa gggtttgatg atgcccgcct tttggccggc aatctgctcg
    48121 agcgtgtccc cgagcatgtc tgcgtggtca tattcgacgg tcgtaatgac cgcgagctca
    48181 ggcgcgatga cgttggtggc atcctgccgc ccgccgatgc cgacctcgat caccgcatag
    48241 tccactttgg ccgccctgaa cgcgaaaaag gccgccgcgg tcaggaattc gaacggagcc
    48301 agttgaaggc cgtgcacgtc cagaaacgcc ttgacgtggt tacaggcatc gaccagctca
    48361 tcttcgccga tgggctcacc gttgatcgca atgcgttccc ggaaattcgt gacatgcggg
    48421 ctcgtataga cgcccaccgt caatccggtc gcccgtatca gcgcaccgat catgcggctg
    48481 accgtcgtct ttccattcgt gccggtcacg tggatcgagc gataggccaa atccggccgc
    48541 ttgagttcat gcaggcagcg agcgaccgct cccaggctga cggtgccgtc ggacggctgc
    48601 ccccgcagga tgcaatcgac ttcaacgcct cgcaaaaatt cggtcacttc ggcataggac
    48661 gagaacggca cggtccaaga cggaggacag gtcttcgttc gtctaccccg catacacacc
    48721 tccctggctg gggacagttc aatgccgctg atcaggcctg cgggactggc gcttcaccca
    48781 cctgttcagc catatccgcg acgacaaacc atttgccgcc atcataacgg taatatttgg
    48841 cctcggccgg ctcgcaggcg atgagtagca gccaccggtt gttgaacagt ttctccagga
    48901 gcggctgccg ttcgatgatg gcgctgaggc gttccctcgg cgcctcgatg atggccgtga
    48961 ggcgcatcgg ctcgtggtaa ggggcctctc cacgcatgac cgtctgagtc ggcaagccca
    49021 tccgaaggtc gctctgactg cccgtcatca cgccgatccc gccggtcacg ttatgataaa
    49081 tcttgctgcc gctgccgaag acctcggggg atacggcgga aaaatagtat tccatattga
    49141 tccactgcgc gacgatcaag ggcgcggtca tgatgatttc gagcagcttg ccgtcaccat
    49201 ccatggcatg gtcgtatgag tgcaggaacg agcggccgtt cagatcggcc tcccgcgtca
    49261 atcgcctgct gcctacgata aagacactat tgcgcgacaa gccccattcg ggacgcacct
    49321 gcgcccaatc cacgctgcgc cgttcgagtt cctgccgagc cgcgcgcgtt ccctcatgcg
    49381 attcggcggc cgtcaaggcc acccagcgtt cggccgccgc ttccccgccg gcctcatgaa
    49441 catcgtccag gatttgggca agttcctttc gatgagttga ggggacatct tcgagatcgg
    49501 cgacctgaac ccggtcggtc gtcgtatcgt ggagggcggc gacaaactgt gtatccggag
    49561 ggatcgtcaa ccctctcgag gccaaaatct cgcgaacctg cgggcgattg gccatcatgg
    49621 caaatgcgcg cgcgttggga agtccctgtc ctccaccgca agccccgcaa tccaaagacg
    49681 actcatacgg attattttgc gaggtgctgc cgtgaccgca tagcacgacc aatcgagcga
    49741 aggatccggt gaggcccatc agtcgcagcg atgtctcgac gtagtacgcc tgctcattga
    49801 cggtaaaccc ggtccgggta atgcgatcga gtcgggagcg agtccctcga tacgtcagcc
    49861 ggcattcgcg gcgcagcgtg accagtgcat ccgtttcctc tgtggagcag acacccaaga
    49921 gccggccgag ggccccggga tgcgaggcgg attcctcatc ttcctcgagt gcttgacgcc
    49981 ggacctcatc caacacagct cctgtgacca ggcttccagc ccgttggcca tgtttcctta
    50041 accaccaggc aatctgcaga cgttgttcgg cggcaagcat gttctccgcg tcggcggtcg
    50101 aaaacttatc gaccgtcaag gtggtggcga ccggcggcac gacccaggat ttgacccagg
    50161 cggcaaatcg atggtaccag cgggggcaga gcgttttccc gaggaagggc aacaggaaaa
    50221 accagccgag tgcctcgacc atgacgtagg gcgtgacgac gttgtgcttc aagtcgtgga
    50281 gcagttcgtg gcctgccttg acgagatggc tgctgtgctt gcggcgttcg gccattgcgt
    50341 cctgatacgt cctcggcacc tccctgatga ggtgtttcgg tttcaacagg accgggcaga
    50401 gcggcagttc ccgctgctcg tccaacgaac gataggagaa cggcacgcca aagaaccccg
    50461 cgaatccgta cgtttcatac cccccgcgat tctcgagatg cctccgaaac acctcggacc
    50521 gtacatcgat gcagaacacg aactgggcga ctggtcgcgc cgtcatcgcg cccggcgcgg
    50581 cgatccgcgc gtcctcacct gctggcagct cgagtttgcg cagcacctcg cattgatgac
    50641 tgcgttcgaa tgcttccagc catgccacac gctgtttagc cggagtaaac tcccgcatcc
    50701 atcgtaacaa catagcgagg tcgcctggcg aagtagacgt gatctcgtgg accggcacgg
    50761 cgagcgcgcc cgacaggctc acgagattct gggcttccac cctgtaggtt cgctcaccgg
    50821 caggctgttc ctcaaaccac cgccggcaat cctgttccca ggcggctgga tcgtatgacc
    50881 ggcccgctcg ctggaggcgg gaggcttcag gcagcaaagc tgaaggaaga tccccggaca
    50941 tcgaagctct cctgaaccag agcgtgtatg gataccgttt cccatactcc agcactgcgc
    51001 tggccgttcc ctcgcacccc agcgaggcac ggcacgcggt cgcgacaagc tcgcgttcat
    51061 aaaacagccg gacggcaaga tacttcacaa gatcgatgcg atagaccgac tgccagacgt
    51121 gcgcatcctg gtcttcccgc cacttgataa atcccgccca gcctggcaag gcggccaggt
    51181 ggcgcgacaa atacgattgc cagattgcgt gggggatgtg gagcatctcc agcgactcca
    51241 acaggacgtc ttcagggcgg tcggccagcg ccgcaatttt cgatgccgcc cgttccaccc
    51301 ccgcacacct gagactgaaa tcgtatcgcg cggcagcttt ccatgcgcgg aaaaatgtct
    51361 cttcccgctt cggcatgggc cacgccgcct ccccttcgtc gcaaaacgcc gcgcaccact
    51421 tgatcatctg gcggttgatt tcatccgtga tggtgacgcc gagcgttcga tcgcaccagt
    51481 cggccatcgt gctttcacaa ggccattccc cggggatgta ctgcaaaccc gccgccctct
    51541 ccgtctctag tgtctcgcgg ggaagcatgc gccccaacca cgccgccagg tgagggacgg
    51601 tcacggagtc tcctgtgggc gtaggcgggg ccgtcgctgc tgtgcctacc cgatcgtggt
    51661 cgcggcccac tgccaccatg atggctctga ggacatccag gtgagtaacc tggcgatcgc
    51721 caaacgtgat ctgccgatcg cccgcctgcc ctcgcaaggc ctcttcgaaa tgtttctctt
    51781 gaatgcggcc tcgacgaaat gcttcccgga aggcttcccc cgagagggtg cccgatccgc
    51841 cgaacagctg ctcagcccgt tcgaccgcct catcgaaacg gagatgctcg aatccctgca
    51901 gggggtttcg ggcgatcact gacgtcatcg gccacacctt ggcgatggtc tctccggcga
    51961 ggctcacata agaccgcaac tccattcgtt gtgcgtcgcg atgacgctgg tccgaaccat
    52021 tcgttgtatg catgccgtcc ctcactttgt ccctgtgtca cagcaagaac ggggccaacc
    52081 gtctcccgca ccaccacaga tgcggctggc tctgatttgt tcggaaggtc gcgattcaat
    52141 atctgcctcg cgacgcggcg gaagccggtc ggcaaggtcg aggcgtgcaa gggtacacga
    52201 acgtgcaacc atgcacgtcc gtgcagagcg caacccgttg aacagggaac gtgggccatc
    52261 aatgcgggtg cataggagga gctacatatg gccgagcttc cggagggttt ccatgccgcg
    52321 tccttcgtct tgtgcgcggc cggctcgttc ggctgtcgtc gtgcggcgca gttcggtgat
    52381 gatttgaggt atggtggagg cgcaggaatc aactgtgccg gtgcagggga cacaacctaa
    52441 gctccgatat cgtgtgccgg ctcccctgtc gaaatatggg ctcggcagct caattcgttc
    52501 ctgttcgaga tattcccaga tgttcagctc ggtccaatcg agaagaggat gcacgcgaat
    52561 gtgggaaccg ggcggaaact tcgtctgaaa ttgttcccag agctccggcg gctggtcgcg
    52621 aaaattccac tcgccctcct tgccccgcaa agagaagtat cgttccttgg cacgcgtgcc
    52681 ctcctcgtcc gctcgaatgc cgaggataat ggccgaccag ccgtgctggg cgatggtctg
    52741 gttaagggca tcgattttca tggccgtgca gcacacaacc cggccgcggt ccggtcccat
    52801 gccgtcggcc agcgccgcct tgttctggcc cacgatgaga ttcaacctcc agtcgcggca
    52861 tatgcgatcc cgatattcga tcaattccgg catttcgtac cccgtatcga tgtgcaccag
    52921 cggaaaaggc acgtggccga aaaatgcctt gcgggccagc cataacagca ccgtcgaatc
    52981 cttccccatc gaccataaca tcgccaagcc gtcaaaatgc ttataggctt cgcgcaagat
    53041 ataaacgctc tgatcttcaa gctctcgcag gtgtcgcata gcatctccca ggcactagat
    53101 gaattccatc cgcgcaggtt ttccagtcgt tagcctcacg acccgctcgt ggccggatcg
    53161 actatcaaac cgtccttgca atatgaggtc ccgttaacaa cgaccacccc tggcttcctg
    53221 cgggagggcc atatgccggc aggggacggc agagacactg tccggcaacg aacgggtctg
    53281 gaacggatga gtggatagat gcgctggttg tgcgcggaca gaccttcccg cgcacaggtg
    53341 tgtgcctgcg caccggggcg cagcgcgccg tcgcagtctt gtgcggaaga caggtggggg
    53401 gtgggaatct ggactgctag tatgccttgc ggcgccgatc gagcatccag cgcgtgatcc
    53461 ccaggtgctt tgccgccagg gttttgttgc cgtcgcttcg ttcgaggacg gcctgaatga
    53521 tggcatcctc gaggtcgctc agcgaccgct cgccgacctt gaaagacagg ctgaccatga
    53581 gcgggtcggc ttcagcaggg gccgccgtag gctgaacggc tccggggagt ccggggagtg
    53641 aggcgggcgc caccgccgca gccaggtccg ccggaaaatg agccgcatcg agtgacggac
    53701 cattgcaaaa gatcaccgcc cgttcgatga gattgcccag ctcccggacg ttcccgggga
    53761 agtgataggc ttgcagtaat tgtctcgcag actcggtcag ttcgcgaacc ggcttcttga
    53821 gggccagcgc cgaccggaga aggcagtgtt cggccagcgg aatgatgtct tccggccgcg
    53881 ctcgcaaggg cggaaccgtg agcatgacga cgttcagccg gaaatagaga tcttctcgga
    53941 attctccctt cgcgacagcc gccttcagat cgcggttcgt cgccgccatg aaccgcacat
    54001 cgaccggcac ggtattcatt cctccgaccc gtcgcagcga ccgctcctcg atcacccgca
    54061 acagcttggc ttgcagcgcc aagggaagat ctccgatctc gtcaaaaaag accgtcccgc
    54121 cttcagccat ctcgatcagc ccgcatttac ggcctgcggc gcccgtgaat gcgcccttct
    54181 catggccgaa gagttcgctc tcgaagaggt ctcgtggaat cgacgggcag tcgacctcga
    54241 cgcagggctt gctgccacgc gcactgttgt agtggatcac ccggcccatg tactgcttgc
    54301 cggttcccgt ttcaccttgc aacagcaccg tgacgcggtc gttgcgcacg agttcctgga
    54361 cctgggccag aaaacttttg gtgaccggac tcttggcgat cacgcgatcc aacgcgtacc
    54421 gggcggcatc ctgaccgcta tgcaactgca cctgacgctg aagggtcaag aaatcggtca
    54481 ccctgcgcag ggtgtggagc agatcgtcca tatcaatgga cttggccacg aaatcgaacg
    54541 cgccgagccg catggcttcc accgcatctt tgaccgttcc tctggccgtc agcacgatga
    54601 ccggcagagc gggcgacatc tgcttcaccc gcgcaagcac atcgaggccg gatagattcg
    54661 gcatcaccaa atcgactatg aggacatccg gctcgaagga acgcagcagt ccaagcgcct
    54721 cctcgccggt ctccgccgtc tgcaccacat agcccttgtc ccgcaaacgt aatgcaaagg
    54781 cctcgcgaac cgacgcctcg tcttccaaca acaacaaatg ccacgccatg tcaggcgcct
    54841 ccatatggac ggtggtccgt ccgcatcatc gataggccat caccgaaaaa cgctacgttc
    54901 agcatgctgc tacgcctcgt gtttgagagg aagccacaca tcgacgactg ctcccctccc
    54961 cggagggctc tggatcacca gctggccgtg gtgccgctca accatatcgc gggtgatggt
    55021 cagcccgagc ccgacgccct tggcttttcc cttggtgaag aatggctcat agatccgctc
    55081 cagatcgtcc gccggtatgc ccttcccggt atccgcaaat cgcatcaaca ccccgggaac
    55141 ccgtcgggct tccggcacaa gtgtgacatg caagtggccg ccgcccggca tcgcatcgat
    55201 ggcgttgagc acgatgttca agcagacctg cagaatgtgg gctttggaag catcgacaga
    55261 gggaaggtcc ggcgcgacgg aggtcttgat caggatctga ttcttcacga tgttcggccg
    55321 cagcagagtc aacatatcgt ccaataccga agcgaggtcg caggacgtga tatcaaacgg
    55381 gcgggggcgc aattggccca agtgggactc caggagttca tcgatccgtg cggcctcccg
    55441 cgcaatcagc cggcaccggt cgcgcgcttc ctgaggaagc gaggcctggt ccgcgagatg
    55501 ggtggccaga ctgcccaacc cgatgagggg attcctcacc tcgtgcagaa tgcctcccgc
    55561 gagctggccg accagcttta cttgttccgt gtggcgcagg gcttccaaca tttgttcgcg
    55621 ttcgctgaga tccgtgagaa tcgccatgaa atactgggtc gtcccgtcgg aggccttgac
    55681 ggggttgaca ctctcccaaa cgaggaattc cgatccgtct ttccgccgat tcacgaaccg
    55741 ttcgacaaag ggctgcccag cgcgaatgga agcccacaaa cgatcataga attccggcgg
    55801 atgctttccg gatttcagaa tcgccgggcg ctgccccaga gcctcttctc tcgtccatcc
    55861 ggtcatccgc tccagagccg gattccattc cagaatccgg ccggtcgtat cggtcatcat
    55921 gacgccgtcc tgtgcggaca ggaacaggcg atgatagaag tccatctgcg tttcctcatg
    55981 ccaccggcgc tcgaggaccg tcccgatggt gttggccatg gtgcagagaa actcctgctc
    56041 ctgctggctg aacttgcgca cccgcttgga gtgggccgtc atgaccccgt agaccctgtc
    56101 ctcgactagc atgggcacac acatgcccga cacggctcca tgttcggtca acaaccgcga
    56161 aggcgagaag cgcgtctcgc ggcgtaggtc gtccacgaca accggaagac gcttggcaat
    56221 cgcatacccg gcttgagaat gcgtgccgcc ctcgatggtc agttttccga tcagttcgct
    56281 ttgcaagcct gatccggcca tgatgtacag ctgaccatcg tgggcgcgcg ggaccaggat
    56341 tttacacagc tccacttcca gcgcggcggc ggtctctttc accgcctcat tcatgagctc
    56401 ttgagccgac acaccgctga cggcgagcgt gccgatgcga gccaacaccg attgaaaccg
    56461 ggctacgtgg gacgcatcct gtgcgagcat aacgcgttcg gtcacatcct ccagcaccat
    56521 aagtacgccc cgctcaccac gatagggcac gacattgaat cggcagacgt agtagagacg
    56581 cccgccgtcc cggccttcga gctggtattc cacgctcttg cgttcgccaa gcggccgatt
    56641 gttccacgca atggcatcgt cgaggagccg tttgcgcagg gcatgctcat ggccctcgac
    56701 cctcggaagc ccgctctcga ccaattccgc aaattgagaa ttttcgaaga tgagaatgcc
    56761 tttgcagaca aacgatagtc ctccctggat gcaatcgctc agccaggcca gtacttcggc
    56821 cgcggcgatt tcagactgga ctggccggga acgcgtggtg gggctgcggc gggatgacgc
    56881 catcaggtct cgtctctatc gggtttggcg gatgatttca ttcagcgctc acagtcgcgc
    56941 acgcggaaac ggggcgcctg cgacatcgaa aagccgctgt gcacccccta gcaatctagg
    57001 gggtgacgaa atggtctcga cgcgtcacgg ctacgtcgct gacgaacatc gcaccggaat
    57061 gtttgtgaaa caacgggcca agccccgcca ggatgggctc gatccgttcc tcaggcacaa
    57121 cggtgaagac gatcacctgg ctgctcgtat cattgaacag cagatgcccc tcatggaatc
    57181 catgatggcc tttgcccgac acattgttga tgatggtata cccggtcgcg cccacccggt
    57241 cgagcaggct ggtgacgatt ttcaaatgtt ccccctccac gacaatgcga atctctttca
    57301 tcggatgcag cgtcagcata ctccgtctcc cttcctctat ggattcatcc tcttttgctc
    57361 gaatgccgtt gcttcctgaa ccgaccccac cgtttcacca tccttctggt gcagaaacgg
    57421 cgctgattcg cgaacgaagc ggggagcagc agcggacgac tgctccggca agccggacac
    57481 cggctgccag ccccgcatga tgtcataatg ataaaaggcg ccttcgctcg cctcgcacac
    57541 gaccagcaac acccattcgt tgtggaacaa ccgctccagt cccggatggg tggcaatgac
    57601 ggattcgaca cgggttctcg gcgcttcaat gatggtcaac agccgcatgg gctcgtggta
    57661 cggcattgag ccgtcgagca cggtctgcgc gggaagtccc aggcgaagat cactattggc
    57721 tccactcatg acgcccaccc gaccgacgat attgtgatag accttgctgc cgctgccata
    57781 gacctcgttg tcgacggtgg agaaataatg ctccatgttg atccactgcg cgacgatgag
    57841 aggcgcggtc atgatggctt ccagcagctt cccggaactg tcctgccggt gatcgtagga
    57901 atggagaaag gcgcgcccct gcaaattcag cggccgggtg agttcacgcc gcccgacgat
    57961 gagcaggttg ttcctcgaca agccccattc cgggcgcacc tgagcccagt ccacgcttcg
    58021 tctggccgct ttggtatggg gatcctttcg cgaccacgtg gcgacgggtc cccctaacgc
    58081 caggccccgt tcctgtgccg cctgggcgcc cgcttcgcgg agatcctcca ggagccgtac
    58141 caggtctttc cgatgagtcg caggaatatc ttccatgtcc acgatccgga catcgttccg
    58201 cgtcgtatca tgaagcccag ccaggaaatg cgtatcgccg gggattctga tgccccgcgt
    58261 ttccaatacc ttccggacgg ccgcattatt tgccatcgac gcaaaggcac gcgcattggg
    58321 caggccgctg ttgcctccgc acgcgccgca atccaaggcg gattcgtagg ggttattgtc
    58381 cgaggtgctc ccatgggaac agatcaccac gagacgcgaa aatcccgacg tgaatcccat
    58441 gagacgaagg gccgcctcga cgccgtacgc ctgttcggag acggaaaagc catgctgggt
    58501 gatccgctgg agtcgcgacg acataccacg cggcgtgagg ttgaaatcgc gccggaatcg
    58561 ctcgtacagc gcagcgactt ccacagggga gatgccgagg atgtgcgcca cgtccccgcc
    58621 cctttgtcct tccgcatctt ccatcacgcc gacacggatc gcatcgatca gcgccggggt
    58681 gatggcggaa ccgagggcag gaaattcctg ccgcaacgcc gcacgaatga ccgcgcgctg
    58741 ctccaccgca accatctcct ccgcctcttc tctcgtgagc ttatcgatcg tgagcgtggt
    58801 ggccaggggc ggaacccaca ggctctttaa cgaagacgtg agacgttggt aggcaagggg
    58861 gcacagggtt ttgccgaaaa acggcagact gaaaaaccat cccagtgctt ccaccatgac
    58921 atagggggta atgacgtttt ctttcagatc gtgcaggagc gtatgcgcca cgtggctgag
    58981 ctgggcaaac aaccgatgtc gacttgccgc cgcgccatgg taactgcgtg gaatctcgcg
    59041 gatgtggttc ttgggtttta acaacaccgg cgcatgggtg accggatgct cttctccgaa
    59101 cgcctgatac ttcaccggta tgccgaagaa ccccgccacc ccaaaagtct cataacctcc
    59161 caactgctcc agatgccttc ggaacacctc ggaacggacg tcgatacaaa acaccatttg
    59221 cgcgagcggg cgcgccgatc cggctggtgc agctcgatca tcggtggcgc gaagttgttt
    59281 cgtcacggcc cgcaattcgt caactacgtc gcggcgatgc ttggcttcga gggcttccag
    59341 ccaacgctgg ccttgttggc cggcgggaaa tccatccagc caattcaaca cggtcgccgc
    59401 atccgccact gaggtctgac tgatcagcgc cggatcagtg ccgagcgccg cggccagagc
    59461 aagcaaccgg cgggcgtccc gcttcatcgc ttcagtgcca cgccactcgg acgtttgctc
    59521 atagagacgg ctgccgacct ggttccattc atcgagcgtg gcagcctggt gggaccgacg
    59581 ccactcttcg gcttcccgga tcgcccatgg tgggatggtt ctggccgtca gctggcgccg
    59641 taaccaatgg gcataggggg cctgatcaag gatggcgcga atggcatcgt actgtcccgg
    59701 ccgatttaac gcgcgcctgc agtgatactc gacaaattcg cgctcgtaaa agagccggac
    59761 cgccaagtac ttcacgaggt cgatcgggta ccgcacctgc cacggatggt gctgctcctc
    59821 cgctctccat ttgatatatc ctgcccagcc aggcaaggcg gagaggtgca aggcgaagta
    59881 ggcttcccag gcagacttcg gtattcccag atccaccagg caagagagga ccgcttcttc
    59941 cggacgctcg cctaaagcat caatctttgt agccgcatcc tgaatcccca gcagccccaa
    60001 gccggcatcg taacgggcca agcgtttcca ggcgcgataa aacgtctgct cccggttggg
    60061 catgacccag gacgcttcgc cttcgtccag aaagacgctg caccacttga tcatctgctc
    60121 attgatgtcc gacacgatgc aggttcccaa ggtctggtcg caccaggccg agagcgtctc
    60181 atgggacaag aggtcaagcg actcccaggg caccaatggc tccggctgac gaatccgcgt
    60241 cccggccacg gcggtaccga gccaggccag tagatcatcg agagcggtat ccccggccgc
    60301 cccagagtcc tgcagtttcg ccggtaaatc gaccaggcca tgcaccatag aaacgcgcat
    60361 cagctccaga tgtgtcaatt cgcgccccgc aaaggtcacg caccggtcgc tggccagagg
    60421 cgccagcacg caggacacgt cattcaggcc gatgcggcct tgctcgaaga aacggcggta
    60481 gatggcattc gacagatagc cctttccacc caacaaatgc tctccgcgtt tgatggcctg
    60541 ggggaaaggc atatcctcca ttccatgcaa cgggttatgg tgaatgaagg tccgcatggg
    60601 ccagtactgg gcaatcgctt ctcccgccag ctcgacatgc gagcgcaatt ccatgcgctg
    60661 ggcttctgtg aaggcacgtg tttcaatggc cattcagtga ctccgacttc gattccattg
    60721 cggggcatct caccggcgcg atcccgcgcg gccgatcatg cgcaccatgt cctcgatata
    60781 gaggccgttc aggaaggcga cgtaggcacg agtgcgcaag gactccatcc accccggcat
    60841 gagtactttg atgcccttcg cttttccgta gatcagcccc caggctccga cgatcatgat
    60901 agcggagact cccaccaccg cgtcgaacag ggcacgattc cattccgcag cctgcacgta
    60961 cgacgcggca atgccgtgag cgggatagag gaaatgcgtg aaggcttcac cggcccagag
    61021 atacgtcaaa ccgatgagag ccagcgcgcc gagcatggtc agggagacat tccaagacgc
    61081 tccggcgtgc aggcgataca ggctgaacat ggcctgcgag gtcgtcaccc aaccgaagaa
    61141 caggaaaatg accgtacctt gcgactcctg caaaggaata ctcacgacgc catgcgccac
    61201 cagcagaata atcaacggca acaccagcgt cacggcgagg cctgtggtcc aggtcatcgg
    61261 tgaaaaggcg cggctctcct ccacccggtt gccaggaggc agtttgaatt ccgtcctggc
    61321 cttatgaatc tgcgcgccgg agttgagaaa cagcgtcgct ttgaacaggc catgggcgca
    61381 gagatggaac actgccagcg cgaaggcccc tagtccacat tccatgacca tatagcccat
    61441 ctgccccatc gtggaataga ccagtgtgcg cttgacgctg gactgggtca gcatggcgct
    61501 cgcgccgatt aacgccgtca ggccgccgat gacgaacaac aggtgaagcg tggtgggagc
    61561 gagaccgaac agcggcgcca ttcggttgac cagaaatccc cccgcgttta cgattccggc
    61621 atgcatcagt gctgatacgg gcgtgggcgc ttcgatggtg ccgatcaacc agaagtggaa
    61681 cggaaattgt gccgacttgg tcatgaccga cagaaccagg aggagcgtcg tgacaagagg
    61741 gacgttcagt tcgagcgcga gaccggacca gctcgtcacc ggtgccgcct gcactcgcgg
    61801 aaacagctcg gtcacgtcca acgtgccata cgaaccatag aggatgagca agaccagggc
    61861 aaaggcggcg tcacccagac tttgcaccca gaacgtcttc tgcccggcgt ccctcgccgc
    61921 gaggctcgcc gggttgcaca ccaacaaggt cgcgagcaac cacgtcacca gatgccagca
    61981 ggcaaacatc cataacagat tgccgctgct gacgaggctt aataacacaa acgtgaggct
    62041 gccgagcaga gcgaagaagc gggtataccc cgcatcgccg accatgtacc gctcagagta
    62101 cacatgaatg accaagctca cggaactgat gagcaccatc atgactgcag ccaaccgatc
    62161 gacgagaatg gtatacgacc acgctcctga gggagcgccg gcgagcgtga ggcggatggg
    62221 atccccatag gagaccagcg ccagcgtgac cagcgatgtc agcgcggagg cccataacgc
    62281 tcctatcccc agccgtgaca ctcgttcgcc catctctcgc cagaagaggg cgattgatag
    62341 cgtgccgaag agtggcgcca gaatcgttac caatggaaag attgcttcca tcataggtgg
    62401 ctctccaaat gaatcatcat gcttcctcta cagcaagaac agggcctgat tcagacgtgc
    62461 atcagactcc gaatgaatcc ggaaaatgcg tgcctgtaga ggatgtccgc tgcagccacg
    62521 ggtgcctcaa cgcttaagta ttgtgcgcgg acgcacagct gtgcatatgc gcacaatcag
    62581 gaagttaagt gcaagtcagg cttacactga tgtgggactc ggcagcgggg catgctgcgt
    62641 accgacgcgc ctttccccct gccattggtt ccccagctgc ggcgaggctt tacaccccgt
    62701 cacacgtcct tcgattcgga ccgtggcttg atgtgataac cggcctatga tagcgtttgc
    62761 aatgcatgct gtctgcagga caaattcgca ccagtgaacg ccgtcggatt gcacacgtct
    62821 tgcgcggctg gatgatcctg tggctgctcg ccttgccgtt gttccacatc catcccgaaa
    62881 cagacccaca tcatggggag gccggtcatg tccatgccgc cgcagtgcat accgtcttct
    62941 ccggtgacct cgaaggcgaa ttcggcgaac atcaagagac ggcctctgta agacctcatc
    63001 caggtgaagg gccggcggtt tcagccgaag gtgcgcatgc ctggagttcc gatccggaac
    63061 tcaacctgtc tctactcaat gacgccaccg accgtaagct ggccaaaccg ctactgacgc
    63121 atctcctgtt tgtcgcccat catctggtac ccctctttga ccagcaggac ggtccgcacg
    63181 gtgagccatt gtcctccacc gtcaccatgc tcttcaccag ggatgtgccg gcccgtgctc
    63241 cgccctcccc gttcttcagc taagtatcac ccgttttcac cgcagacatt ctgatcgcac
    63301 gcacgtctcc gcgaggcctg ttccggctcc cgcccgacga tccgtgcgga atggaggagg
    63361 tttccgatga tgcctcgtat ggtcctttcc ctgctgatgg cctgcgtctt cagccaatcg
    63421 ggcgccttgt cctgggctgg agaagaacgg cctcgcgcct attcgctgtc ggacgttctg
    63481 acgttcgcgg cgcaacacaa tcccgtgctc gcgggagctg agggactggt gaaacaaagc
    63541 caggggcaac agattgctgc cggcgcctat ccgaatcctt ccatcaccgg gattgccggg
    63601 cgcggcgcga tccgtgaccc cagtaccgga acccacgtca ccgagcggac gttgaccgtg
    63661 gaacaacccc ttgaatggac cggcaaacgg caggcccgcc aggaagcggc ggatgccggc
    63721 ctcgccggcg cgaacgccgc tctggaggac gcccggcttt cattgctcgc tgatgtcaag
    63781 attgcgttct atcacctcct gttcggccaa cgcgatgtcg aactgtccgc tcaaaatgtc
    63841 acgaatgtgg aagaggtctt gcgaacggtg caggcacgcg tgacggccgg tgaagcgaca
    63901 tctttcgaca gtctgaaagc cggagtcgag gtgcaaaagg cgaagaagga agtggctcgc
    63961 gccaacaacg cgctgctggt ggccagggca cggctgaata ccctcactgc cgggacactc
    64021 ggcaaggagt tttccgtgca aggcgatttc gaccggccga agcagagcct caatgcagat
    64081 ggtctgaccg cgcaggcctt ggagcaacac cccgccgttc gacgcttgag caaactggcg
    64141 gagcaggccg accatacgct gcgttttgag cgagaggccc gcgttcccaa cgtcagtgtg
    64201 atcggaagtt accatcgcga ggcgggcgac gaatctctca cggccggcct ggccgtgccg
    64261 ctcccgctgt ggtaccggcg gcaaggcgag attcagtccg cattgggcgc caaacaccgt
    64321 gccgatgcgg agcgcctgcg ggctcagcag gaattggagc aggccatcac ccaacatgcc
    64381 caggaagtgc ggacggccca ggagcaactg caggtcttcg aaacggggtt gctgaaacag
    64441 gcggagcaga ccctcaccgt ggcacgaacg agtttccggc acggcgcagc cagtcttctg
    64501 gatgtcctcg atgcgcaacg ggtgtaccgc cagactcaac tcgaatatgc ccaggtgcga
    64561 gcggatctct ccatcgcact ggcccggctc gaacgcgcgc tgggaacatc attatgaacg
    64621 ccgaccgcag tggatggact attggagtgc cgcgatgacg agacgactga tgacgatcgg
    64681 catggtgccc gcgctgctct ggcttctgtc tggttgcagc gaccagggaa cgccgccacc
    64741 aaaacctgcc acgaccggcg aagcccagac aattaccggt agcagtaaag ccatccaccc
    64801 gccgccggca gtccaggctc gccttcgaag cgaacctgcc gccctgcgtg cggtacccac
    64861 actgatcaca gctcccggtg aggtggccct cgacctgaag caggtcgcca aaatcacgtc
    64921 ccgcatcggc ggacaggttg agcgtatcca tgtgcaattg ggagatcgag tcaagaaagg
    64981 ccaggcgctg gtcgccatcg gcagcctgca actcgatcag ttgatcgagg aatatctcgt
    65041 cggaaaggcc caagccgacg tggcggaaaa cagttttcgc cggaccgaga aactgcgcgc
    65101 cgacgacatc gtcacggagc gcaagctgat cgaagacaag gggctctatc tcgagacgca
    65161 ggcgcgttat caacacatcc gcgaacgact gtcgaacatg ggcatctcga cggatgactt
    65221 gaaacaaggc ccccatgaga agagccatct ttacaccctc accgctccga tcgcagggac
    65281 cgtcgtcatc cagaacgcgg tgcgcggaca gggagtcggc cccggtgatg aattgtttga
    65341 gatcgtcgat accagccgtg tctgggtctt tgccaatctt cccatcgagc aggccaggca
    65401 attcaaggag ggcgactccg gtaccatcac gccgaaaggc ggcgaagcca tcgtcgcgcc
    65461 gctcacctac ctgtcgccgg tggcggacga gaccacccgc accattcgcg tgcggttcga
    65521 ggtagccaat ctccaaggac agttgaaacc acgcgagtat gtcgaagtgg cactcggctg
    65581 gtccggggcc ccagtgatca ccgttcccat gaccgccatc accacgatcg acaaaacacg
    65641 cggcctgttt ctcgacaccg cggatggcta cacgttcgtg ccggtcgacg caggccgcga
    65701 aggcggcggg tgggtggaaa tccgtcgggg tgtgaaggaa ggcgaccgga tcgtgaccga
    65761 cggcgtgttc gatctgaaaa atgtgctgct gaaggaacac atcggctcgg gcgaatgagg
    65821 cgcgcatgca acagctactg acgttttcac tccgctatcg attctttacg ctcgtggcca
    65881 tcgtcgtcgt gattgcctcc ggcctgtggt cgttcgcaca cctgacgatc gatgccgtcc
    65941 ccgacctgac cccagtgcag gtgcaaattc tcacacgcgc cccggcgctg gggccggtcg
    66001 aggtggaaca attcgtgacg tttcccatcg aagcctcctt gaacgggttg ccggctctgc
    66061 gcgagctgcg atccatttcg cggtacggcc tttccgcagt taccgcgatc ttcgatgatc
    66121 gcaccgacat ctatcgagcc aggcagttcg ttgccgaacg attggctcag gccatggaac
    66181 gcatcccggc ggaatacggc cgcccggtga tgggccccct cacgaccgga ctgggcgagg
    66241 tctatcaatt cacggtgaaa ggcgaaggct ttagtccgat ggccctgaga acgctgcttc
    66301 agtgggacat cggcatgaag ttgcgcgccg tgcccggcgt agtcgaggtg aatatatggg
    66361 gaggcgatcc gcagcagttc cacgtcatcg tcgatccctc gaaattgttg tcattcaaat
    66421 tgtccatgaa gcaggtgttc gatgcgttgc agcgcaacaa cgccatcgcc ggcggcgggt
    66481 atatcgaaca ccagcgcgaa caactgtcga tccgcggcga agcactggca acacagctca
    66541 gcgatctggc ccagatcgtg gtagcccacg ggcctggcgg cgtccccatt tatattgctg
    66601 acctggccga agtgaaagaa ggatcagcgc tcaggatcgg agccgccacg gccatgggtg
    66661 agggcgagac cgtcatcggc atggtgcaga tgctggccgg agaaaatgcg caggaggtgg
    66721 tcactcgcgt gaaggcgcgg gtgcaggaca ttcaggccac cctccccgcc ggcgtcacca
    66781 tcgaacccta ttatgatcgc acgatcttcg tctcgaaggt catgcagacc gtccgcaaca
    66841 acctcctgga gggtggtctg ctcgtcatcg ctgtcttgtt tctctttctc ggcgacctcc
    66901 gcgcagggct catcgtcgcc tccgcgattc ccctcgccat gctgatcgcc ttcatcggca
    66961 tgatgcaggc cgggctctcc ggcaatctca tgagcctggg tgcgatcgac ttcggccttc
    67021 tagtcgatgg ctccgtcgtg atgatcgaca acatcctgcg acgactgggc gagaagccgc
    67081 caccaaccag ggaagcccgc ttgaaggaag tgctggccgc cgggcaggag gtgttgcgcc
    67141 ccatgacgct ggccgtgacg atcatcattc tggtgtacgt cccgatcctc gcgctgaccg
    67201 gcatcgaagg caagatgttc cgcccgatgg cggtgaccgt catcatggcc ttgaccggtt
    67261 ccctcttcct cgccctgacg gtcaccccgt tgctgtcctt ttggttttta cgcgccactc
    67321 ccggcagcga aacgacggcg gtcatacggg gcgtgagaag agtctatgcc ccatggttgc
    67381 agcgggccgt ggcccgccca atctggcccg tgtcgattgc ggtggggctt tttgccgtca
    67441 gcctcgtggc cggaagcagg ttaggaatcg aatttgtccc gcgtttggaa gagggggacc
    67501 tcgcggtgca ggtatggcgg ctcccgagca tctcgttgag cgaatcggtc accaccgcgt
    67561 tggatatcga acgggtcctg aggcgttttc ctgaagtcac gcgggtcgtc acgcgcaccg
    67621 gcagccctga agtggccacg gacgtcatgg gcgttgagat gtccgatgtc ttcgtcatcc
    67681 tgaaacccca gcgcgattgg gtcacggcac acagccgcaa cgaattgatc gaggcgatga
    67741 aacgacagat cacggaccag gtaccggggg tcggacttgg attcacccaa ccgattgaaa
    67801 tgcgcttcaa tgaattgatt gccggcgtgc gctcagacct ggcggtcaaa atcttcggtc
    67861 ccgatctcga catcttgaag cagcaggctg aacgggcggc gcgggcgctt caacatgtac
    67921 cgggagcggc tgatgtcaaa gtggagcagg tcgccggctt acccttactg cgcgtcgttg
    67981 tcgatcgcgc tgagatcgcc cgttacgggc tcacggctga agaggtgctc acgcttgttc
    68041 aatcggcccg ggtcggaacg attgtcggga cggtcgtgca gggttcccgg aggttcgaat
    68101 tagtggtgcg attggcggac cgggtctcgc gtgatcctgg ttcattgggc agtctgctca
    68161 taccgaccat gcatggagaa ctggttccgc tctcacgcgt gaccagcatc ctcgtcgatt
    68221 caggtccggc acaggtgagc cgggagcatg tacagcggcg gattgtggtc gagaccaaca
    68281 ttcgcggacg cgatctcggc ggatttgtat cggaggctca acaggccgtg gcccaggcag
    68341 tcacgctgcc accagggtat gagttgatct ggggaggaca atacgaacac ttgcaggagg
    68401 cgggcaaacg tctggccatg gtcgtgccgg tcacactgat gctgattctc ggcatgctat
    68461 ctgtcatctt cggcacacta cgccccgccc tcctcatttt cctgaatgtc ccacttgcct
    68521 tgtcaggcgg catcctggcg ctgtggctgc ggggattgcc gctcagcatc tcagccatta
    68581 tcgggttcat cgctctgttc ggcattgccg tcctcaatgc ggtcgtcctg gtcagccaca
    68641 tccgccagct ggaggcggaa ggggtttcca ctcgggaagc ggtcctgcac ggagcgatgg
    68701 atcgtttgcg gcccgtgttg atgacggccc tggtggcaag cctgggcttt ctgcccatgg
    68761 ccttggccac cagtatggga gccgaagtcc aacggccgct agccaccgtg gtgatcgggg
    68821 gattgctgac atcgacagcc ctgactctgc tggtgatccc ggcgctgtac tcgcgcctgg
    68881 tcccgcaggc tgcgtcccgg ccccatccgg cagctgtaca ggcggacgat agcgccattc
    68941 aggtgtaacc ccccgtggca tcacgagaaa tcgaccacca gccgcacgtg atacggcgcc
    69001 gcttccgact cttttctgga cagactttca tcccggcggt aagctttcct ctacgaggcg
    69061 aagtgtctgc acgcaagcca ggggcctgcg cagccgctca agcgaattca taaccggccc
    69121 attttcccga ggagtagttt atggcgacca tcatggtgat cgacgacgaa ccttccatcc
    69181 gcggcctcct gcgcgaggtc ctggaacgat caggacacaa ggttgtcgaa gccaaggatg
    69241 ggcgtgaagc gttggatctc taccagaagc ataaggccga tctgctcatc atggacttgt
    69301 tgatgccgga agtggatgga ttggaagcca cgttgcagct cacccgcgaa tatatggaca
    69361 cgaaaatcat tgccatgacc ggcgctcagg gggatcggaa ttttctcgat atcgcccggc
    69421 tcttcggcgc gcaccggact ttcgaaaagc ccttcgactt gaaggaaatg ctgaacgccg
    69481 tggaagcgga gctggcgcag aaataacctc gcaccggcca atccgccggc tcacctgacg
    69541 cactcgtcac tcccgggaaa aactactgga atcaccgccg ctgcttctgc aagaattcac
    69601 cgtgcagcag acccccacag ccaggttctc gtgtttctaa cccccactcg cgcatggcgt
    69661 ctctggtgtg cctggagcat gctgattgtg ctcgtgggca tcctgcctct ccataacttc
    69721 gtcggccatg cgcattggca gtatattcgt tgggtgccga cgccggatca attgagttcc
    69781 ccggcgatcc tgctggatct tgccttcgat gcggtcgcca atatcctgct cttcgttccc
    69841 ttcggcctgc tctacgcgct tcgcggcctg gaaggcaaac ctctttctcc gcgccatctg
    69901 ttgttgatgg cctttgcgct gtccttcagc atcgagtact accaggtcta ttgtcataac
    69961 cgcagcacgt cgctgctcga cctgctggac aatgtcttgg gcgcatacct ggggatgaaa
    70021 gcgggggaag tgtatatcag aaagaatgcg tcagcagtgg tcgaaccggc cgcataagat
    70081 tattgccagc ctgtcgggtc atagccccgg tctcgtaagc accgatcgac ataattcgta
    70141 aacgccgcgc cgggcggaga ccgtttgaac agtcctcgca aaaaccctgc ggtagcgccg
    70201 ctggctgcgc cgaccattgc accccgtccc gggtgtccga gaatggctcc gcccaccgct
    70261 ccggccgcag aaccgacagc gccgcctccc actgtccccg tcacgacctg ggccgtcttg
    70321 ccttcactgg aagacgcccc ggcctccttc gccagcgcca tgcaatcctg gatatcagcc
    70381 tgcgcggcat cggccccgac ttgctggtag tgagcattgg gatacagaat gggtttgggg
    70441 gcagcgcagc cggaaagcac gagacccaga acacagagac aagccatttg cctcatgaca
    70501 cagacctccg gtgcgctgaa tgtttgaagg gaacgtcagg ccggcccggt gatggtacgg
    70561 tataaattag atccggccac ccaagtcctt gcgctgcagc gtacgcatca tgacggaatc
    70621 gttgtacgcc acctcgctga gcgcatccat gatgtgcagc cctttggcag tgaccaactc
    70681 tttggccttg gcataattct tcgcactgaa ccgcgcgacc gcaggctgac cattcacaat
    70741 ctggcaggcc aggacttcac cgccggcgac atccatcgtt cccccttctt caaccagctt
    70801 tttcgcctgc ggcatcgtaa tctgatgcaa ttgggcaaat tcctccagcc cgccggtttc
    70861 cacgagacgt ccatcgggca tgatgcacaa ccgtttgaaa tggggagacc agtctttcct
    70921 gaaatcgatg aacttgatgt cgccgccttt ggccacggca cgatccagcg tgcggtaatc
    70981 gaggccaaga tttttctggg cgagtttggt ttttaattcc tccggcagcg tccggtaaaa
    71041 gatctctccg gcggcatcga tcaatgagac ggcgcgcgcc ctggcccatt gctccgcttc
    71101 ggcgaactgc atgagatcca gcacccaggt ctgcttggga gaagcccccg tcggatctac
    71161 ccggcaggca aagagccccc gcgtgagcag cccccccact tggggataca cgtacacgcc
    71221 cccgtctgtc aggagctgca gcatctgctc caacggcaca tcgtaacttt ccgccaggat
    71281 cttcgcatgc gccgccagat cttccggcaa ggtcatggcg cacaccgtga cgtttcccgg
    71341 cgcatcgaat tccgagtaat cctcgatcac gttgtacaga atcggcggct ttggcttctc
    71401 gatcttcttc ttgatcttga acataatgaa ttcgttcctc gtcgttcgtc tttcgttcac
    71461 actacgtgcg gtaaattact gcggtgcaat cacccgcgct ggaggtggta gtaagccggc
    71521 aaggtcagca gccgcccgtc gtccaccggt ccaccaatgg taaagtgata gagtgattgc
    71581 agcgtcaggt ccttgatgcc gacgatctcg tgcacgggat catcaaaata acagccgatg
    71641 cccgtccctc gcacgccggc tgcttctgcc tcgagataca atacctgccc gaccagcccc
    71701 gcttcccaga aaaggcgtgg ataccaccaa gccccgccct gccgcaagcg cccctcaaat
    71761 tcggccaaca tgccgagtga aaacgcgctg tcaccggcga tgccttgatg acaactgact
    71821 tgggcagcca ggcgttgcgc attgccttgc agcagccagt acagcggaag atctgtcgga
    71881 cacccaggca ccggggtcca ctccaattca ggattcatcg cctgctgcag aagcggcagc
    71941 ttcttcgcat cccgcgccat cacatagagg cccggcgtca ggccctccac ccggtgcacg
    72001 aacaacagca gatgaatcgc cgggtcccag ggcaagagat cccacggcat gggccgggcc
    72061 agttgcggtt ggctggcgtg aggtatcagc cgaaggagaa tctgaaaaaa cgtagcgctg
    72121 gaaattgccg tgcggccatc gaacgacacg gcgctgcgac gctgtctgat gatggtcgcg
    72181 gcgccgcgcg tggcttgtgg gtcgtgacgt ggttccgaat gcacgggcgg ctcaacgggg
    72241 agagacacca ccaggcgctc ttcacctgtt ttccatgagg cctccgctgc ttcgtcgatc
    72301 gcttcccaat gcacgccatg ctcgcgactc aataggttcg catggccatg ccatggtccc
    72361 ggcgccagat ccttcaccac cgtttgatcc acacccaacg gcaggttttg aacatcgtgc
    72421 ttcatgttgg gtgaaggcca gatcacggca agacagtcgg gatgctccgg ttcggcctca
    72481 ccaaaatcct cctggcgatg ggtgcccaac agccgcgcga cctgattttg ttccaccccg
    72541 tccagcagca ccatcctcca accaagcgtc gccgcggcga tacgcgcgga accaagggcg
    72601 tgccccacgt cgtgattgca atagcgaaag gcccgctctc catacttcca ggcttcgcgc
    72661 caatggacgg aactgaggcc gaatagaaat gcgccatccg gaaacggcgc gagcagctgt
    72721 gtgatcttcc cggacggaag gcccgcgcgg aactccaagc catgttcctt ggctgcatag
    72781 tgatagaggc cgggcggcag atccaagcca tcgaccggcg gaacgatcac atagccttcg
    72841 gtcggatgca gattgccgga cgaaggattg ctgcgaaggg cccactccga ctcccctgct
    72901 cgcttccagg ccgacagccc gagcgccagt tcaaaaaacc gtgagatcgt cttgatggtc
    72961 aatggccggg aggccactgc gcctggttga tagagagcat cgtaagaggg cgactgcgga
    73021 tcgtcatccg ggctcagcaa cggtaaacgg atcagttgcg caccctcaaa ccgccgaaac
    73081 ggattgggtt gatttgccca atccagaaat cccaacgatc gcgcgtatcg attgaaatga
    73141 tgcttggttc gaatgtgata ggcgatcaca cggtcgattg gatctgtcga agtagtcccg
    73201 gcagacgcgc cggaagacgg ttggtcgaga gtcatgcgcg cagtctaacg aggcggagga
    73261 aggaaagtaa acgcacagtc cgttcagccc aggagtcttg cgatcccgaa ggccgccgct
    73321 gccgcgagtc ctccgacgaa caccgtttgg actccgccac gccagggcgg cacaccggtc
    73381 aatccacttt tcacgtatcc gaaaacaaac aaggccacgg gcgtcacggc aatcgaccac
    73441 cacagcgccg tcgcaatctc gtggaacacc atgtagggca acaacggaat caatcccccg
    73501 atcacatacg agagcgcaat cgtccaggcg ctcgacctgg cacgcgccgg atccggttct
    73561 tccaatccca actcaaaccg catcatgaag tcgacccacc ggcgggggtt ggctcgaagg
    73621 gaggcgatca gcggagcaat gtgttcatcg cgcaacccgt agccacgaaa aatctcggcc
    73681 acctcctcgg cctccgtttc gggaatatgc tcagtctctc gcacttctcg cttgcgttca
    73741 gcagcgtaat gctcaagatc ggtcttggcc gcgagatatc cgcccagccc catcgcgatc
    73801 gagccggcgg cgatttccgc caatcccgcc gtaactacta aagcggacga agccaccgca
    73861 cccgacaatc cggcggccag ggcaaagggg accgtcaacc cgtcggccat gccgatgacg
    73921 atatcgcgca ccgtcgccgt ggccgtgaaa tgtttttcac tatgtggagt cgccggcata
    73981 gggatactcc ttccaaacgt gaacagcccg atgagctatc ggcatcgaat cttgctggct
    74041 gcggtggtgc ttgtgtacgc gggttgacag tgctggtcaa gggaaggggt cggagtggtg
    74101 gagcggctcc tccggggtca cacggatgtc ctgatggcgt ggggagcaaa aaccgagttg
    74161 agtgaagcgg cgtgaatgtc gccggcgacg cctcctaaag ctggcatcgc cggcagatgg
    74221 ttcagtgatg agcgtaggac taggccgcca ttgcagcagg gctgaacaac ttcaccgtat
    74281 cctgcaattg gtccagcgcc tcctgcagca acatcggccg atcttcggcg ttgaaacggg
    74341 tcgtctgcaa ggccgtcgcc tgaaagggca aatctttggg cgcacgcgta ggagacagct
    74401 catagtggtc ggccaccacg cctgccagat gcaccatcga agcatggagt gaaaaatcgc
    74461 cggcatcctc ggggcacaac tgatggcgga tcgcctgctc gatttgaacg ggcatgcccc
    74521 aagaatggac cagttctgcg ccgacttccg tgaaatcaca tccgaaattc gattgctcga
    74581 cttccgccag cggttcgccc aaattaccgg cttcgatcaa tgccgattgc gcccgttcgg
    74641 gaattgtctg gtacagcacc aggtgcccga tgtcgcgaag cagaccttcg atgaaaaacc
    74701 gctcgctgtc ttcgatcccg caggctttgg caatcttgcc cgccatcaat gcgcagagca
    74761 cgcttttccg ccaataagcg gagagatcca tgatctggac ggtcatgcca ctgaagctgc
    74821 ggccgaccgt cgtcgcggtg acaagatcgc gaaccgcctg catgccaagc aaattgacgg
    74881 cccgggttac cgtatcaact tgtttcggaa agccgtagag aggactgttg acgatcttca
    74941 gcacgcgggc ggaaatggcc gggtccatct tgaggacctg cgccagatcg tccatagtgg
    75001 aatcagggtt gtcgacgacg tcgcggacac ggaaatatat ctccggcagg gtaaagacat
    75061 ttgagcagga ctgaa
//
LOCUS       DAOQPD010000009        69663 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_130_length_69663_cov_20.811904, whole genome shotgun sequence.
ACCESSION   DAOQPD010000009 DAOQPD010000000
VERSION     DAOQPD010000009.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 69663)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 69663)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69663
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_130_length_69663_cov_20.811904"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            373..1482
                     /locus_tag="PK063_03775"
     CDS             373..1482
                     /locus_tag="PK063_03775"
                     /inference="COORDINATES: protein motif:HMM:NF024098.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HMZ96191.1"
                     /translation="MADKSMEEDDYRVEAQATGKRQEQIEKEKEDLLARMGSSDISTM
                     RHRVAWVLNHFPSTRNSDIALQIKYWECFDSELYRGSPIEVDDLYRLTRLTSVARERA
                     RIQNQYRLFLADEDVQQRRGTLEDEEREKAIEIPDCPVYKVYLDESGKTTNHLIVGSL
                     WFLSSGTEGFELYRQSKDLKDKHDFQHEFHFSQMKKDELVVYKELVDIFLTQGGTISF
                     KSISVPRAGIKNVSDALGDLYYLLLTKGVEQENSTGRAPLPRILQVWKDAEEIGSDKI
                     LMANLADRIKQTSASLYENKLFVQEFVAADSKSSIFLQVADLMASSVNRILCRGEQPR
                     NQKDELADYLVQRLGISTTPDLEVLMGDIAAHIRL"
     gene            2243..2860
                     /locus_tag="PK063_03780"
     CDS             2243..2860
                     /locus_tag="PK063_03780"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96192.1"
                     /translation="MKLVLVGINHFDPLCKESLARTLIELRNCYGLPPAFVAVEWDES
                     LFSKVCAQRAAFREKCRLEWPDAGEETLKVLEASLGFEGDTHREVFGDLQTLWLDQGR
                     QGNVENYASQRFVMYKDFLREKTNKDCPTMLSKLSVVARHRQGRLDAGTQRDQKWEEL
                     LLERLSKGPGLWAICVIGAGHIANIPGGIRTRLEAKGQQCEIVNL"
     gene            3045..3497
                     /locus_tag="PK063_03785"
     CDS             3045..3497
                     /locus_tag="PK063_03785"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96193.1"
                     /translation="MELFEEFVLAYLTKDKHVFVNPQYSIRDEVSGGEWSCPDFLVLN
                     FKDKKVSVVEVSTGYDLKNLVEKVNNREIHWFNKLKKQLVRSGVIDNDSHWDFAIQVF
                     IRKERDKFFRQTIHSHDRVEVMSLEDLGFPWSKSWHVEQHNDTSSSKH"
     gene            3513..4721
                     /locus_tag="PK063_03790"
     CDS             3513..4721
                     /locus_tag="PK063_03790"
                     /inference="COORDINATES: protein motif:HMM:NF012618.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WD40 repeat domain-containing protein"
                     /protein_id="HMZ96194.1"
                     /translation="MLRFSAGHDDEHETAPFDLNTDRGLMFRKAILIAAIFMLGVDHL
                     LAGGQDFDAASFSTVLEPSSNDYSLEEQRVTSMALSPSEGLLATGDLDGTLKIWDVQT
                     CKLLKILLVKESEDPRLSDGIGITSLTFSPDGRWLAGGSRDRVIRIWKVAPLPSIQET
                     YKVSGHQGAVRSLAYSQDGRYLASVGGGTIRTWKIDGQVTEMAVFPTDNLHDFAVLLS
                     RDGQTLFSGGHENVVRVWDLKTGTITRSLNVPGRVRALALSPDDRMVAAALEAKGPEW
                     TGISIKVWNSQSSQLMLDLEAHGESALSVAFSPDGQRIASGGADGNAHVWNVNTKTLL
                     QTMSPISEEKPRKWFDQETTTLAGGTIQTVKFGGDGRRLFTAGYGYPPRVWDVNSGKV
                     LKIFRGQGCS"
     gene            complement(5233..5988)
                     /locus_tag="PK063_03795"
     CDS             complement(5233..5988)
                     /locus_tag="PK063_03795"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96195.1"
                     /translation="MPNWLAYAGAILTGLIPPLIMYLIGSQKKVLGYALTQNEPMINL
                     RHPDLDGRLSMSLDGKNLNGCRIMGLVIQNLGMKDIEEQSVHLTFPAGVTVLHAHCSS
                     SALAIGPKIEARQADSHEVRIPLMNPGDKLMVRLLMTGNEAGRILVTAKGPSLKFKPF
                     DPTTFISPAVNRGLLVMSGAIFAWIVWACAGTDRFMARPFWDKTITLALIGLFLAIPS
                     AILAYQGTIPLLKRALQWREGNRASSLQPHPEL"
     gene            6393..7907
                     /gene="gvpD"
                     /locus_tag="PK063_03800"
     CDS             6393..7907
                     /gene="gvpD"
                     /locus_tag="PK063_03800"
                     /inference="COORDINATES: protein motif:HMM:NF018756.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gas vesicle protein GvpD"
                     /protein_id="HMZ96196.1"
                     /translation="MTDPTRQADSRCETGIDGLNEILGDGLPANCMYLVQGDPGSGKT
                     TLALQFLLEGVRLGEKTLYITLSETKEELVTVARSHGWSLDSISLFELSAIDSLVRPE
                     ARTTVFHPSEVELTKVSEMLQSEIRRIQPARVVFDSLSEFRLMAETALRYRRQLINLK
                     QELAKYNCTALLLDDRMDNSRIGGDPHVLSLTHGVIEMEQLSPDYGRSRRRLRVLKMR
                     GMKFREGYHDYSIEKGGLRVFPRILASDHRADFSPQAVSSGNQEFDELLGGGLDRGTT
                     TLIMGPAGTGKSTLAMQYAAQMAQRNESSVLFAFDEIRGIVLARATAVGLDVERHINT
                     GLIDVQQVDPAELSPGEFGMRIREAVEGGCTLLIIDSLNGYLNAMPGEKYLVNQLHEM
                     SAYLNQKGVVTILILAQYGLIGQAEAPLNLSYLADTVVSVRFFEAAGAVRQALSVIKK
                     RSGGHEKTIREYQLVSDGGLRIGPPLKQFQGVLTGTPSFYGALEQVMERPDGAN"
     gene            7894..9960
                     /locus_tag="PK063_03805"
     CDS             7894..9960
                     /locus_tag="PK063_03805"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ96197.1"
                     /translation="MVRTRLEERIIILAPIGQDAPAMARVLISQGVDAIVCATALDTC
                     RELAVGGAVLLVTEESLELPHISQLLHHLKAQPPWSELPMIVLTRGGESRLARLLDLV
                     AEAAGSITLLERPIGEATLMRSIEVGLRSRRRQYQVRDLLEQETLSQQQLRESEQQYR
                     TLFESIDQGFCTIEVLFDEQQEPVDYRFLLVNPAFAVQTGLRDVVGRHMRDIVPQHEE
                     HWFRIYGNIATTGEPLRFEKEAKALDRHYEIYAWRIGLPSEQKVAVLFNDITQRKASQ
                     FRLEQFAEELERKVSERTYELVASQQQLRALATELNLAEQRERTRLAAELHDHLAQML
                     VLVRLRLGQAKVGPLSHSIQMIKQAEDVVDESLTYTRNLVAELSPPVLHEFGLFVALR
                     WLGEQMRRYHLEVSVRIDTPEELKLPENQAVLVFQSVRELLLNAVKHAGSKKAWIAAA
                     SEDGVLSIVVEDRGVGFDPITLSSQKLAAMSSKFGLFSIRQRMEALGGRLELRSKLGE
                     GTKATLVLPITQLSEQATGISLSYIAPSAHVARAPSTGHCKSVPYRVLVADDHAMVRQ
                     GLCLMLDACPDIEVIAEAANGQEALELARRLKPSVVVIDINMPLMNGIEATAQIRTAL
                     PDTIVIGMSVNASVDNQEAMRTAGASVLLPKEAAGDQLYGAIQSAMKGLSEHTGPLIR
                     SQETRL"
     gene            10067..10234
                     /locus_tag="PK063_03810"
     CDS             10067..10234
                     /locus_tag="PK063_03810"
                     /inference="COORDINATES: protein motif:HMM:NF023180.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3309 family protein"
                     /protein_id="HMZ96198.1"
                     /translation="MPNIVLVILILLLVGVLPTWPYSSGWGYYPSGGLGLLLLIVLVI
                     ALSGRRGALRS"
     gene            10373..12508
                     /gene="glgX"
                     /locus_tag="PK063_03815"
     CDS             10373..12508
                     /gene="glgX"
                     /locus_tag="PK063_03815"
                     /inference="COORDINATES: protein motif:HMM:TIGR02100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004133 - glycogen debranching enzyme
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen debranching protein GlgX"
                     /protein_id="HMZ96199.1"
                     /translation="MTEVLEGRPTPRGATWDGQGTNFSLFSAHATKVELCLFDPTGEK
                     EIDRVSLPEYTDQIWHGYLAGIHPGTPYGYRVHGPYDPDAGHRFNPNKLLLDPYAYAH
                     MGELQWNPALFGYQMESGDDRTFDERDSAPFMPKCTVVDQNFDWSGPRDRRTIPWDDT
                     VVYEMHVRGFTKLHPAVPSTLQGTYEGLATKEVLDYLQSLGVTSIELLPIHTFVNDSH
                     LLEKGLTNYWGYNSIGFFAPDPRYAANRPESVRECKEMIARLHDAGFEVILDVVYNHT
                     AEGNELGPTLSFKGIDNSSYYRLQPEQPRYYINDTGTGNTLNLSHPRVIQLVTDSLRY
                     AVQQMHVDGFRFDLGTILAREPNGFDNRSGFLKVCSQDPLLATVKLIAEPWDCGPGGY
                     QVGGFPPGWAEWNDKFRDDVRDFWRGELAATNLADRLCASASVFNHQGRRPWSCVNFV
                     TAHDGFTLHDVVAFNEKHNEANGEDNQDGSSNNRSWNCGAEGPTEDASINALRDRQMR
                     NLMATLLISQGTPMVLAGDEFGRTQRGNNNAYCQDNEISWVDWSLLETRSSLFQFVKE
                     LIAFRHHYPILRRNLFLTGQLAEDSGVRDVTWINANGGPMEEHHWTDTTIHCFGMLLD
                     GRAPTTGRRQPGKDVTVLVLINGHHEPVQFTLPPCVGASEWTLLLDTNLPDRPQNQTF
                     QMGTQYLLTDRSLVLLVLGAKRTEEIIPV"
     gene            complement(12640..13872)
                     /locus_tag="PK063_03820"
     CDS             complement(12640..13872)
                     /locus_tag="PK063_03820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HMZ96200.1"
                     /translation="MSDFHQNGLVTVLHRLGGSNLEQLEKELERHAASNPIALVLPSL
                     YSELENPALKHIVQVLKDIRYVNEIVISLDRASALEFRLAKQFFSVLPQRVRIVWNDG
                     AGIQDILKLLAQAELDTGLQGKGRGCWMAFGYVLARGESNVIALHDCDILSYNREYLA
                     RLCYPIVNTNLGYEFCKGYYSRVTNRLHGRVTRLYFTPLIRSLQQVAGAHPLLTFLDS
                     FRYPLAGEFAMVRDLAWINRVPGDWGLEVGVLSEIYRNCALRRICQADIADAYEHKHQ
                     GLSADNAEQGLQKMCVDITKSLFRNLASEGVVLSEGVLKTLRATYLQSAQEAITRYQN
                     DAAINSLQFDRHAERMAVEVFLKGMKIATEAFLEDPLGVPMISNWSRVTGAIPDVFER
                     LIGAVERDHDWDPVGDRV"
     gene            complement(14004..15305)
                     /locus_tag="PK063_03825"
     CDS             complement(14004..15305)
                     /locus_tag="PK063_03825"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96201.1"
                     /translation="METPELNDYRAHLLDALDDQPRRAAEERPGFLQVLVNHERIGTL
                     NCSQTDPSFAYTARERSIQHLELRSESGVLIGGCVAPEAGQKSVRIPVGKGSLTLHVQ
                     NHFDGGSLNVQYEVAPGWWSHLATAIGLPAGAAVASTQGSPVWSMTTAFAQVVLAVGV
                     VALLAERIPAWVGSEDRAHQLEEELAARQSTQDQIDHVHQQLAQLVESQAAAVAVSRA
                     EQDRIAQLNTLIDTVAHTQQRLSTQVVAVQEDLKTVKTDVAQEVQTGMRVAVTAVEAD
                     RELVRQDLQAVKSVNETLVKQVALLESRNRELHARLALTSLEVAKANAASKPVVVAKN
                     EPPKETPAPTAVAVSDNLRDADRQAFMFWVAFQDGTTEKSIEDLVQELNGIKKGPMKS
                     GWYSVEVNLPNPEPPDRFLESVKRAKIVKSVVTSKAMPPAQ"
     gene            complement(15262..16224)
                     /locus_tag="PK063_03830"
     CDS             complement(15262..16224)
                     /locus_tag="PK063_03830"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96202.1"
                     /translation="MSPKMPDGKTMRDGQPFSARLNNVVTTEREFDELVTKSLPELLD
                     RATGQTKRFLRETNQWGDDITHEKLALRWGYELVERFVVFGRTEVPCRPFFLLDSLIA
                     KSFSQPDPLCYHKELLTPVGRFLDGLASRAVVSRDALIALFYHFYGFSQAHVVKLLGF
                     GQAESQRVYKNFERWRQSGWQRTMNETGLSGPEIEILEQELRTRPDHLNNEVDRLMPV
                     LQSHYRKSEPEHYPCLSEQKWGQLFHDDYGHDYRVWHLAFCRDCFLEVADRRQADVSS
                     GVKPQVNLHIHPLKKGGVLALFGGDRGGRHHGNTRAQRLSRTSA"
     gene            complement(16414..18066)
                     /locus_tag="PK063_03835"
     CDS             complement(16414..18066)
                     /locus_tag="PK063_03835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-binding protein"
                     /protein_id="HMZ96203.1"
                     /translation="MTTHTIGTAVLDRLHRLGVRHMFGIPGDYVLSLYKLMESSPIQH
                     VATTREDCAGFAADAYARINGIGALCVTYCVGGLNTVNAIACAYAERSPVVLLTGSPG
                     LSERARNPYLHHMVREFSTQREVFEKMTVAAVSLDDPLTAEREMDRAFAALLRYRRPI
                     YLEIPRDMVHVPLAYTSHKTSILDEPTDKAALSEAVTEVRVMLESAKRPVILAGAEVG
                     RFGLHDELTKLVERLNVPIASTLLGKSIIREDHPLYVGVYSGLVARDEVKEFVNQTDC
                     LLILGSILSDVEDLDARSALFSDGHTIHATADRVAIKHHRYDSIRFEDFVKALANAPL
                     PSFPKPQLPAPRAPEEPMPPADASVSLHGVFRHLDTVLQEKTLVIADVGESLFASVDL
                     HVHRRFEFLSPAYYTSMGFAVPAAVGASFADPSLRPIVLVGDGAFQMTGSELSTAVRY
                     RQAPVVIVLNNHGYSTEREILEGPFNDIHEWRYERICDLIGGGQGSRVATHGEFVDTL
                     AKALADPSQPYVINVLLDPSDRSPAMMRLARRLAKRLSTDRP"
     gene            18266..19462
                     /locus_tag="PK063_03840"
     CDS             18266..19462
                     /locus_tag="PK063_03840"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF022137.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HMZ96204.1"
                     /translation="MTQTMTSSTARVRLTAERAGPRYYGHLWVFDNNVAEVLGTPAAG
                     DLVDVYTHQKRFFGRGLFNPHSKIRIRLLTFHEEPIDEAFFAARLRAAAALRRTVTPH
                     ANACRLVHGESDLLPGLVVDRFADVAVMQALGYGMDLRKDLLGDLLVQEAGVKSVYLR
                     NDAKSRTLEGLPLSKGFLRGEGPTTVPIHEGKAQFTVDIAEGQKTGWFCDQRENRLAA
                     AAYAKGKRVLEAFCHTGAFGVQAALAGAQSVEGLDVSAAAVALAQAHAAQNHVASICT
                     YRQADAFDELRVLERNQQRYDLVILDPPAFARSKKALPHALAGYKDVNLRGLRLLQSG
                     GVLVSCSCSQPVSDDDFWMMLQSAARDANRQIRLLEQRGQGPDHPVLAGMPETRYLKC
                     FIVQVF"
     gene            19467..21476
                     /locus_tag="PK063_03845"
     CDS             19467..21476
                     /locus_tag="PK063_03845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0035673 - oligopeptide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006857 - oligopeptide transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transporter, OPT family"
                     /protein_id="HMZ96205.1"
                     /translation="MMHEPERLSEPVDAPLVPASVSLPEITPKAVLLSVLLAAVLAGA
                     NAYLGLFAGMTVSASIPAAVVSMAVLRLFRQSNILENNIVQTAASSGEALAAGVIFTI
                     PGLVLIGYWTSFDYWQTFTVSLVGGVLGVLFTIPLRRALIIHARLRFPEGVATAEVLK
                     IGATSGGNAGRRVRLLLSASALGGGLKFAEGGLKLWSESLEGALELGRMTFYGGLNLS
                     PALVAVGYIIGLNTALVVFLGGAIGWLVLLPLYQALVGTPADVTGVAAAKVVWSGQIR
                     YIGIGAMLVGGVWTLIQVRGPILHSLRQLLSLYAARRDDRGASAPLRTERDAGVVWLI
                     GLTVASLIPMVFLYRHLLDHSLFAGAGLTVLMVVTAFLFSAVAGYMAGLVGSSSNPVS
                     GVTIATIMLAALLLLAILGREHPAGPAAALLVGAVVCCAAAMGGDNLQDLKTGHLVGA
                     TPWKQQVMQVIGVATGAVVIVPVLSLLQAKYGIGVATAAHPHPLSAPQATLMANLAKG
                     VFGGSLPWHLVGIGMALGVVIIALDQRQAQRQAQLRFPVLAVALGMYLPLKLSAAIMF
                     GGLLAEAVRRGRPASETPTDDQGLLCAAGLVTGEAMVGILLAVPIALSSVWPSLAGDP
                     FQLFADPPLGGWPGLLALALVGLFLVRAAQAAGGAGNADATPRGV"
     gene            complement(21503..21973)
                     /locus_tag="PK063_03850"
     CDS             complement(21503..21973)
                     /locus_tag="PK063_03850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HMZ96206.1"
                     /translation="MPHIGALVRAWRVSQKCSEQAFAQRAGITPNLLESLESEQLDPT
                     ASTLEAFAKALQIPLSWLFIHPTEFDLLCKDAEEEPAPLSTLTGADPVLDRLLLAAGH
                     DRTLFVLLTALMQSGDPKLLRAAEVSLRSLVKQSKQATVPWQSRPPGHFEPPSD"
     gene            22150..22491
                     /locus_tag="PK063_03855"
     CDS             22150..22491
                     /locus_tag="PK063_03855"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96207.1"
                     /translation="MLGTDIRGIMAEEEEVQRRQEALQSLMSMRERLLRESLEARIKR
                     ARGTGDWTNLSPAECASIYKEERVHLRAQLERLKAERDRTRGKLSALKRAKVRAQRIR
                     AAEAASGKKRK"
     gene            22560..23369
                     /locus_tag="PK063_03860"
     CDS             22560..23369
                     /locus_tag="PK063_03860"
                     /inference="COORDINATES: protein motif:HMM:NF012797.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HMZ96208.1"
                     /translation="MTFSSRTVSRNFLSHIRDVAKTKRTRDRERVFVLEGTKPILELV
                     RSAPRQIVCLVVAPTFLERQSPGDVQEIVRSGCTVHTCPEHQLAQLSDVETSSGALAI
                     VHQPTWDQAAMLAQPRVFGLYGDMLQDPANIGTIIRTAAGLDVSALWMAPHSVDVFNP
                     KVVRATAGTLFQLPIFSHTSFENLLSLGCTILAADVGAHSNSVPIRSIQSIPARTIVA
                     IGSESRGLSDAVLDAAAMRFTIPLKPGVESLNAATAAAIALFHLSGLPVES"
     gene            complement(23378..23839)
                     /locus_tag="PK063_03865"
     CDS             complement(23378..23839)
                     /locus_tag="PK063_03865"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96209.1"
                     /translation="MTDLIPPTTSRVADRTDADINARIRRQTEANVAYFAKGGAQAIS
                     ERLRELDREWDVERLLEANAATIALTGLCLGSLVNRRWFLLPAVVGGFLLQHAVQGWC
                     PPIPIFRRLGMRTQTEIEQERYALKAMRGDFANIPRDGDDRTAAVLNAVRA"
     gene            24017..25378
                     /gene="radA"
                     /locus_tag="PK063_03870"
     CDS             24017..25378
                     /gene="radA"
                     /locus_tag="PK063_03870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HMZ96210.1"
                     /translation="MKAKTTFHCQACGHQAPRWLGRCPDCGGWNTLKEERLPAAPKGR
                     QAMPLTAMAVATPISDIEIVGEPRHSTGMGEFDRVLGGGVVPGSVMLIGGDPGIGKTT
                     LLLQALPLLAETGEQVLYVSGEESPRQIKMRGERLGIGGKHLLILGETSLEQILKAIQ
                     EIKPAAVVVDSIQTVYTEQLTSAPGSISQVQEVAGQLMWFAKRNNVPVFIIGHVTKEG
                     AIAGPRLLEHIVDTVLYFEGDKSHSFRILRAVKNRFGSTNEIGVFEMKDGGLEEVSNP
                     SELFLAERPQRSTGSVVVSSLEGTRPILVELQALVSGTNYPMPKRMANGVEPNRLSLL
                     LAVMEKRLGMHLSGQDVYVNVVGGIHIDEPAIDLGIVAAVTSSLRESPIDFTTLVMGE
                     VGLGGEVRAISQAEMRIREAAKMGFKRCLLPERNVAKLDPVDGIELVGIREVGDALDA
                     VLA"
     gene            25384..26244
                     /locus_tag="PK063_03875"
     CDS             25384..26244
                     /locus_tag="PK063_03875"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96211.1"
                     /translation="MATKTVRVNQVRQLLSILLLWVFTLPGCALFGPKDTTPLKEATA
                     EQLTALLKEQAGEVRTIKGLFSAKITGGILPIGQRVQGTVFYQRPNAIRLRGFSAVGS
                     EIFEFVQLEDQFKLRLPTMGREVTGRSSEADQLGQLTRPFQLSVWAMSGVTGTQAVGP
                     QEQVRLSEDGSRYRLDVLTAPGPSGAAPYISRRIWFDRRNLLVVQEERLTPAGEIEAT
                     MQLDDYRAVGPLSPATLASNGQSPETVTRIMRPFTIRMTDGQGSGSLQVTFHELVPNE
                     PIKPGELGRV"
     gene            26241..27065
                     /gene="tsaB"
                     /locus_tag="PK063_03880"
     CDS             26241..27065
                     /gene="tsaB"
                     /locus_tag="PK063_03880"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: protein motif:HMM:TIGR03725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HMZ96212.1"
                     /translation="MKVQPDHHLLAIDTATAWQSVALLSGEKVLALVEQDADGSHARS
                     LLGAIDRVLRETSITLKQLQSLAVSIGPGSFTGLRVGLATMLGFRAVLGLPIAPVPTL
                     EAMAWNLRDAKGLLVPVLKSRHNEVYWAAYEWLPESGLRTLIAEQVGPPGSVARALQG
                     SNSCTVFGDGWQAYENDIRNAIEAVGGQVQEVSEETHRPSAVSVGLAGQRRLDGGQIA
                     EQELVPRYVQRTEAEVKFDEQQGVSALERRRQRVASKLTQRRARPVPKGSDVRRRT"
     gene            27093..27599
                     /gene="rimI"
                     /locus_tag="PK063_03885"
     CDS             27093..27599
                     /gene="rimI"
                     /locus_tag="PK063_03885"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: protein motif:HMM:TIGR01575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HMZ96213.1"
                     /translation="MTSTSILIEPATPAVLDEVLAIEQACFSAPWTRKMLAAELSGNQ
                     FANFLIAKCPDPLSGSFAVAGYFCFWVVFEEVRLMNLAVLEPFRRQGVATKLVCTALQ
                     TGVERGASRAMLEVRESNLEAQTLYRRLGFRQTAKRSRYYNHPEEDAVLMEMTPLQVS
                     EVCRQPGV"
     gene            27664..27879
                     /locus_tag="PK063_03890"
     CDS             27664..27879
                     /locus_tag="PK063_03890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcH family protein"
                     /protein_id="HMZ96214.1"
                     /translation="MQTETAITERLRRSNTEFRALEESHHRLDEKLADLQRRHVLTPA
                     EEVLKKQLQKEKLATKDKIAELIRSSR"
     gene            27974..28744
                     /gene="tatC"
                     /locus_tag="PK063_03895"
     CDS             27974..28744
                     /gene="tatC"
                     /locus_tag="PK063_03895"
                     /inference="COORDINATES: protein motif:HMM:TIGR00945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase subunit TatC"
                     /protein_id="HMZ96215.1"
                     /translation="MLAPLAAHIQSLKKRLLIIAVTLGVAFASAFAYSTEMVAWLNRP
                     FPNQLVFYGPTEALFASIKVSFLAGIILSLPIVFYQFWKFIEPALLPKEQRWAIPIFL
                     LAALLFALGLIFCNLVILPLVIDFFVSFGMDRDITPALGVGTYIDFNVKFLLIFGCAF
                     ELPLVLTILSRVGVVSAAVLAHYRKHAIMAALIISAIVTPDATLFTMLLMAVPLMVLY
                     EIGIIGAKIFGRSSGPAPDMNLPLDPDIPIGTAGHRVR"
     gene            28779..29855
                     /locus_tag="PK063_03900"
     CDS             28779..29855
                     /locus_tag="PK063_03900"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96216.1"
                     /translation="MLRHMLVLTALTVGGLQGLVHAAPSLIGNEGGGALKLEQGHPGQ
                     DPSSPADIGNTSIQALASGAGGVIYAGSFGMGIFRSTDRGGTWMSANEGLTDPFVLCL
                     TTAKDGAIYAGTFRGGVFRSRDAGKTWQPINKGLKRLEIKVLMMDAKGLYAGTGDGVY
                     LLNAAQDHWKVVTTGLDEILVHALARTDDGTLYAGTSGKGVHSYKERTPGWTRLRQGL
                     KDHEGLVENFIRVLAVDKEQGVYAGTFDGGVFRSGDGGKTWLPISRALPNDSIRGLIS
                     NERGVYVATGRGIFKTVDKGRQWMPLNKGLSNLSVQVLIEGDKGGFYAGTSSGVFRSD
                     DDGLTWTAVSQGLEGESVAPFKFN"
     gene            29873..30382
                     /locus_tag="PK063_03905"
     CDS             29873..30382
                     /locus_tag="PK063_03905"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HMZ96217.1"
                     /translation="MTAQTGSPQATITVTSKNEPWGQIVLRFFPDVAPNHVKNFTDLA
                     KKGFYNGTTFHRVIPGFMIQGGDPNSKNPDRASHGMGGPGHNVKAEFNSKPHKRGTLS
                     MARANDPDSAGSQFFICVNDANFLDWQYTVFGEVQSGLDVVDKVVGAKRDGRDNPLER
                     VEMTVTITE"
     gene            30421..31125
                     /locus_tag="PK063_03910"
     CDS             30421..31125
                     /locus_tag="PK063_03910"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96218.1"
                     /translation="MTPVLRFLRVTVHLSQVAVLAAAVFTAAGCAIPQVPSRTVYEDP
                     VNFVRLELDANVLPEWPPGHFTHPARFSQEQVRRVLMGLTVQEHRTMVQRWIGDDSRR
                     LPMFRDAEIMILVPQLVEALRLARENERVTYYLSQPQTSVKRTITSGGMYIRGTELHF
                     ILGNWQTLYGIPAYGMIYDRRYPMNPIISKGFDLFFDLDQALVTQTTSIWDGLLANTK
                     DELVIDLAIVFPGQNI"
     gene            complement(31180..32619)
                     /locus_tag="PK063_03915"
     CDS             complement(31180..32619)
                     /locus_tag="PK063_03915"
                     /inference="COORDINATES: protein motif:HMM:NF014385.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HMZ96219.1"
                     /translation="MTYLLLRSTSLMLAALSLAAASASGTYAAEAEQPVPLSRGSFLG
                     VQQAVEIAVKNHPMLIEGQANLKASEARTEQARSLYYPQVYANANTVAGAGVSNPRFL
                     IGGGLLRENQTTFTGGVIANQRLYDFGYTSNLIESNKLAERAQGQDVNARRALVLLYV
                     QRAYLNSLKRHRLVQIAEETVRERGIIAGQIETLYRQQLKSKLDFDLARVELVNAQSL
                     LVRSRNDLKASFADLNRTMGIAGADDYVLEDISVAVRPQKTLETLINESLSHPEVKRA
                     KEQTASADARLTATKRQYLPTVSAIASGGTFDPFDPRQNQQTGGWWMAGAMVSMPLFT
                     GFLIENQVVEANANRQAASAATSNIEQALTQQVTNAYLDTLTFAQQITLAEEQVKTAQ
                     EALQLSKQRYKLGLGTVVEVTQSEVAVTAAQTRLADTQYDYKIAEVTLAYTSQGDDTG
                     RILLMSRASTASRPGDAGSQAEGPPAAAY"
     gene            complement(32616..33920)
                     /locus_tag="PK063_03920"
     CDS             complement(32616..33920)
                     /locus_tag="PK063_03920"
                     /inference="COORDINATES: protein motif:HMM:TIGR01730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HMZ96220.1"
                     /translation="MDEPSTTLRPVRATRRKIRWIALAIVLTLVIGGLLYWREIHDVG
                     HPVPPASPAVPTPPQPPEESVAVPDSAPVDVQVTKPTRRDLVYTVKLPANVSPLYQTT
                     LYAKVSGYLKWIGPDKGDAVKRNDVVAVIDAPEVEEQYQQAVSDYKIKKLTYERLAKV
                     WKESPDVIAKQDVDVAEAAYQGARHLMEQRVVMRDYTKVRAPYDGIVTARFADPGALI
                     QIATSSATSAIPLFTIMDLNTVRIYANVPQDDSPWIVPGKTQATVKVTELPSRSFTGL
                     VTRSTMALDPATRSLLVEIDLPNQDHALRPGTFAEVTLGLREIPQALVVPPQAITSTP
                     KGKSVFVVEDGKAKPVAVQTGISDGRWIEISSGLRGDEDVVAVGKRRLLEGMPVVASP
                     FNLPDAKLSQQKFERRAPGGTPPPPTAAPPTNRAAQTQGDRP"
     gene            complement(33920..37189)
                     /locus_tag="PK063_03925"
     CDS             complement(33920..37189)
                     /locus_tag="PK063_03925"
                     /inference="COORDINATES: protein motif:HMM:NF013069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HMZ96221.1"
                     /translation="MLTRAALKNPYAVFALCMIALILGGVSYQKMRVDIFPEIKLPSI
                     LVTTFYRGLSPSEMEGAITLKMEQRFVEASYVEHIESQSLAGMSYIKVFFQPDYGIDA
                     AQSELTSLAYSIIRLLPPGVYPPSVYKFGVSSLPVGYLSISSDALGPKEIRDLAYFTV
                     RQQIANIPGISFGPPLGGKVRQITVFLDQQRLLARGISPSDVVNALNQQSAIIPAGDI
                     KIGDLDYYVYSNSLVDVVDKINDLPIKIVNGTPVLIRDIGTAADSAAVQTSIVRVNGR
                     EATYIPITRQEGANTLEVTDGIRAKLSKLTEIPAGTTVKFLYDQSLYIRQSIANLQKE
                     GLLGAGLAGLMIFIFLASVKAALVVGLAIPLSLTVALVALYLTGQSVNIMTLGGLALV
                     IGTLLDNNIVVQENLHRHLEMGKDGRSAAEDSAMELTLPILVATICILIVYLPIMFFT
                     GIIKYLFVPLAMTVAFAMLADYVVSMSVTPVVLAWLYQGGHGKGTEHEASADEGWFRY
                     VLAIYEPILKGGLRFKPVVIGLATVALIATGAFLIPRLHTEFFPKVDAGNFTMLVTAP
                     EGSRIEKTTAIVGQVEQLVHETIPKADLEEVISNTGLYYGDAARFAPNTGNHTAFVLV
                     NLITGHEGRTEDYIAQLRSRLKTSLPGVEISFQTGGIISDVLNFGLKAPIDIQVKGPS
                     LDVIRPVAERIQQQIAQVPNTVDVRIKQGKSYPELHIDVDRTKAAYYGINQNRVVVDV
                     ITGISSNLALSPNYWLDPKTANGYFLLAQYPEQSLTTTEDLLNIPIIGARTPLLPTSS
                     LTGGGIQGSTLALQNTPFAGRQMEIASGYYASSDDRRGPPVMLRDVAQLKFKTGPDSV
                     DHYDLSRLINVLVTPVGNDLGHVAKDIEQVLAGIQLPKDVTVQLRGEVANMRGAIQNF
                     ALALPLAVVLIYLVMVALFRSFIDPLIILVAVPLGWIGTVLTLHVTNTSVNVESMIGT
                     LMMMGIVVSNSILLVDFANRMVRNGSTAAHAVLEAGRRRIRPILMTALATILGLLPLA
                     LGFGEGNETMVPLARAVVGGLAVSTIMTLLVVPVMHSLVLIRRERAPLSATAPATSED
                     I"
     gene            complement(37183..37617)
                     /locus_tag="PK063_03930"
     CDS             complement(37183..37617)
                     /locus_tag="PK063_03930"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ96222.1"
                     /translation="MPSSCSILLIDDSPGECELFRQALTQTGYKGRLDIVEGGQAAMA
                     YLHEHVQHEEPALILLDLKLRGERGVDVLKRIKQEARVAHIPVVILTSSDDTADVRAC
                     YSGGANGYVVKPGQFDDLVTLSLHLWKFWLEHNCTQRMAAPC"
     gene            37971..39233
                     /locus_tag="PK063_03935"
     CDS             37971..39233
                     /locus_tag="PK063_03935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HMZ96223.1"
                     /translation="MSDDHSTPDSSRGWRLICTRDFGLLWWGQTTSQIGEGLNKVALL
                     WFVYELTGSAMKMTMVGLLQTIPPLVLGPLVGVYLDRMPKKPVMIWVDILRALLTLLI
                     PTLYALDMLSITGLYGIIFLTSVVSTIFGPALVSAVPLLVRPSELMSANALIQGTNNI
                     GMLLGPAISGIMIALIRAENVLFVNSATFLISALCLMPIRFSPSHAVSSEQATSVWQE
                     LQVGFRFIFGQQSMVLTLVIISSLYNLGVSAFVFILPVYAKEFLQVGPVQLGWLWSAL
                     GVGMLAASAWLALKQESDIQGRLRIVVSGMTIGGLAVCSLSLLETPLIAAGIVIIVGG
                     STAVLNPIIWALLQELTPEHLIGRVVTTFSVGSMASAMAGMTGFGWVADAVGPAASLV
                     ALGLVLLLTAAVAVACVRRTCALPVAHA"
     gene            39394..40647
                     /locus_tag="PK063_03940"
     CDS             39394..40647
                     /locus_tag="PK063_03940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HMZ96224.1"
                     /translation="MSDTHRWLLTRDFGFMWWSQVLSQVAEGVSKLALLWFVYAVTGS
                     PLKTTVIGLLQTLPPILFGPFIGVLVDRFPKKAILITSDVARGLLIGLIPCLVPIEHF
                     TVESLYVLTFLFGMATAVFVPTLSSAVPFMVARPQFTAANALLQSTTSLGIIIGPAVS
                     GLGIAFSGSQDVLCVNALTYFASAACLLPIRLRATEQAPDSSAGWRPFIRHLLEGLRY
                     AFLTHRTLLILIVLASIYTFGSGAFTTLFPVFGRQLLGLGPVEVGYLWSWLGVGLLLS
                     SIGLIWLSAWDLHKRLLAIAVSCALAGLAVVGLTWTDSVGVASAYVVCIGIGLGTWTP
                     IAWGIIQEVAPPGMVGRVMAVYTAMATATSMLGMSAFGWVAESFGSITSVLGIGGVMG
                     VLAWGSAWFGGRIRTVGVTEGGNRS"
     gene            41038..41790
                     /locus_tag="PK063_03945"
     CDS             41038..41790
                     /locus_tag="PK063_03945"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96225.1"
                     /translation="MGATEELAKKFQTPLTDVVSVPFQYNTFFGVGPGNATSHLLNIS
                     PVVPVRLGDWHVVTRTVIPVISVSRFTPGLEDEIPGTGGGTATGLGDINFTPFLTPGR
                     TGAVSWGLGPSITLPTSTMEELGSKKWSAGPSAVVMFRFSPVVGGVLLRQQWSFAGGR
                     HHPGVSQFLMQPFASYNLSGGWFLTSAPIMTANWEAQPGNKWLVPVGGGVGRAFILDH
                     QPMSLTAQAYYHVIRPDLGAEWQTRLTMQFLF"
     gene            42007..42510
                     /locus_tag="PK063_03950"
     CDS             42007..42510
                     /locus_tag="PK063_03950"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96226.1"
                     /translation="MSKFLIQAIVVLALVGPGGQFVRADEGSSKSHHQHLQGVVIEKG
                     GALAVKVPNGSTYQLNENRSERHGHALPKAGDEVTVVIDENNNVLEVHPKGTEGKHRF
                     ITGEVVSIGVMQREITLKTSKGEQKFAMEKQELSSSIKDGARVRAELNEAGSIIDVHP
                     EKSGGGH"
     gene            complement(42586..43107)
                     /locus_tag="PK063_03955"
     CDS             complement(42586..43107)
                     /locus_tag="PK063_03955"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96227.1"
                     /translation="MHKSLRHAAWIIAIAMLPGCVGLGAWTLGTRSESSDHPKIDQTR
                     GAIDLRKAGTPSEFKTVAELRTQWGEPDNIELRKDGREEWIYKTGGLRWSGMVLYLVV
                     IPLPAMIPVGSQYVSLVIHDGRIEQATRRDWAFKAGAYCGFFGMVYGGLGCGTGTFEE
                     KQGSDAQVVNGTP"
     gene            43287..43667
                     /locus_tag="PK063_03960"
     CDS             43287..43667
                     /locus_tag="PK063_03960"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ96228.1"
                     /translation="MAPRRYARTYYRFPLNYPVIFGGAPFVGEGVLTNLSLKGCSVTC
                     DREVLCGSQVRVSMLLHHQPPALPVELGTIKWVRGNQFGVEFVRVPLEAQQRLNRTLR
                     MELIEWLENRHRNSASPASPRHDN"
     gene            43859..47086
                     /locus_tag="PK063_03965"
     CDS             43859..47086
                     /locus_tag="PK063_03965"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ96229.1"
                     /translation="MASDPPPSASSSQDGIQQGGHSWWARLAEWNPSLLTTVTLAVAT
                     GLRMALTPLWGSGYTFITYYPAIMFIAVANGWRHGVAATLVSSVLTIVLFFDMQASPG
                     EQQTALALFITANVIIVSLSEAVTRARLRAQAETSLVRAQEQRLRLEIDARAKAEETV
                     RASERQMQFVTDHAPVLIAQCGTDGRYRFVNQRYADLVRRTPEDLIGLHPREVLGAEA
                     YQQAEPYMREALAGRQVKFDQQFLGAASIGRLLQVTYAPEWDERGIVTGFIAAIVDIT
                     ERKQAEQARATLAAIVESSEDAIVSKDLNGLITSWNRGAERLYGYTRQEAVGQSVLLV
                     IPDEQIEEETPILAKIVRGETVQQYETIRRRKDGTLIDIALTVSAIRNDEGRIVGVSK
                     VAHDITERKRAEAALRESEERLRLFIEHAPAAIAMFDRQMRYVAVSRRWLADYGLEGE
                     VLGRSHYEIFPDIPERWRRAHQEGLAGVVMRIEEDRFERSDGTVYWLRWEVRPWRDKA
                     GGIGGIIIFAEDITDSKKAEDALRESEAQHRATFDNAAVGIAHVGLDGRWLRCNDALC
                     ALTGYSREELLARTFTEITHPDDIEGDWASVRRLLAGEIETFSMEKRYIRKDGSLIWG
                     HLTVSLLRDEQGSAHHFISIIQDIQIRKEAQAQLRQLADDLEQRVEVRTRELADTQDK
                     LRALTTELNLTEHRIRKQLATDLHDYLAQLLVLSRIKLGQAKLEEVTPAAMEAMTEVQ
                     EVMDRALAYTRTLVAQLSPPILNEFGLLMALRWLADQMQRELTVKLDLESDVLSLSEE
                     QSVLLFQSVRELLMNIVKHAGTTEAKISVTQADGVLRICVSDRGVGCDVGPGEAKLEP
                     GFGLFSIRERMKALGGEFDMQSVPGEGTTAILQLPVVQPGPTADEAVAETGVAAVSHA
                     VVSEPAAPGVPKLPTTASLLATPKIRVLLVDDHRMLRQGLRTIVNGHPGLEVVGEARD
                     GLEAIELTRTLSPAVVVMDVNMPRCDGVVATKRIKEEYPEIKIVALSMHNSPDIVARM
                     KQAGAYGYLTKESAGVQLCRAIVEAALSRPSGASGEGRDVSCGPS"
     gene            complement(47119..47499)
                     /locus_tag="PK063_03970"
     CDS             complement(47119..47499)
                     /locus_tag="PK063_03970"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ96230.1"
                     /translation="MVEILVVDDNLQLRDTLRKILNKRPGFRVTGEAADGIAASQLAQ
                     TLRPTVVLMDVGMARMDGVEATRRIRALLPNTVVIGMSCHNSREVEVALRAVGANAFI
                     PKELVPEQIFDVISQQLPQDQTVQ"
     gene            47729..48994
                     /gene="pfp"
                     /locus_tag="PK063_03975"
     CDS             47729..48994
                     /gene="pfp"
                     /locus_tag="PK063_03975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphate--fructose-6-phosphate
                     1-phosphotransferase"
                     /protein_id="HMZ96231.1"
                     /translation="MAIREQRPVVGILVGGGPAPGINSVIGAATIRSILGGSDVIGIQ
                     DGFKWIMDGNTSKVRRLSIEDISRIHFSGGSCLGTARANPTQKTEHLDACLASLHTLG
                     VTRLITIGGDDTAFSALKLEQRAGGRLQVVHVPKTIDNDLDLPHGIPTFGFQTARHIG
                     VELVKSLMVDAETTSRWYFVVTMGRKAGHLALGIGKAAGATLTIIPEEFRHKPIRLQT
                     LVDILVAAFIKRLSAGRSDGVAVLAEGLVEILDQQDLNGLEDVERDQHGHVRLAEINF
                     GFVLKRAVEKELRTFGIKTTIVDKNIGYELRCADPISFDMEYTRDLGYCAAQFLLEGG
                     NAAMVSIQNGRFIPIPFGDILDPATGRTRVRMVDVESESYVIARRYMIRLSSDDLHQP
                     DDLVRLATTAGLASDDFRKRFEYLIGKDV"
     gene            49010..49963
                     /locus_tag="PK063_03980"
     CDS             49010..49963
                     /locus_tag="PK063_03980"
                     /inference="COORDINATES: protein motif:HMM:NF013431.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96232.1"
                     /translation="MMSAPTPDTETTIAFENQRAVLSPWGASLRRYFIVGSSGSETDI
                     VWGYSGGGQKKGGQGDVLIPFPGRVAGGRYSFDGQLLQLERNDKEGPNAIHGFVRSLP
                     WTTHQAVAHAVTYEVSVDAADYTSRGYPFSLVVRLTYSLGIQGLSCTFSVRNVGGAAA
                     PVGVGFHPYFTVGTGLIDEAEAKIPAAGFLEFNEQLAPTGKVIAATGTEWDYRTFQRI
                     GPRRFNHCYLELERDAAGMATASLRNHKSGRTIDVVMDRAFSAVVVYTGDAIADAPRR
                     ALAIEPMTCATDAFNHPDWGLKRLLPGEVFTGSYSVRARSR"
     gene            complement(50034..51779)
                     /locus_tag="PK063_03985"
     CDS             complement(50034..51779)
                     /locus_tag="PK063_03985"
                     /inference="COORDINATES: protein motif:HMM:NF024824.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ96233.1"
                     /translation="MAVPKDRQVRHHGRLLSLSVMLLLTPIAGTGSGAFANDLPLRSE
                     GQIAQHAKAAWEQGTLNLALGIVEQGIQDHPRALALHQLRGDMLATSRQTEAALESYE
                     TVLASIPAALDVRWAKWSVLVRSGQVEEAVAELQRIAVIDPHNPLLHLRLARELRKLD
                     RLEESFEAYQKAVELGPDMLNWRLALARARFDVLDYEGAERDVQFVLDRVPPGSPLHL
                     SARNLLTVFFGSTERGRRFAPVMTPDVSPKQLRDWSMIRAEGYRLFEAGRFREAEPVY
                     RELLRLNPMDPLAGRHLSLILMGLGRCKDALAVSQAGSEFDPTDEEHTTTAFRMGQCM
                     VELGRWEDAYMQFKTLYDATVEFEKSTKDVQLPSGTRVLNKANLVQWLEKVRLHVPEF
                     AQQVDEDAAATAAQAKAAAPTIPPEAELAAKAIEALKPQNTLDPAASLVGRDADFAWF
                     RFVIPAKKVMRDDSPTGAHDFIPLDPGISFPGSQQDIYLVFSLVTASYDEVPLAARCF
                     KETAELAGAHTAVAQDRLIMSTNDQSGYFVLPRPATGWTAGLYRCGLFAGEETSAYTQ
                     VDEVRFRIIEPTRPS"
     gene            complement(52034..53596)
                     /locus_tag="PK063_03990"
     CDS             complement(52034..53596)
                     /locus_tag="PK063_03990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HMZ96234.1"
                     /translation="MPLSTTVHDLRTLIRSSHPLIVIETVEEDRVMTLLQSVAAQERM
                     PLFEWSITRGLTRPEEGPSLSKLTATPLAALQHLNGLTVEGIFWLKDLAPHLQDAAVA
                     RQLREVSHHLSRSRATCVMTGHPITLPLDLDQIAVRFDLQLPDRDELHAMLQSVLQSL
                     RTRTSPRRPTSTTVVQSLLNSMATPKPTMAGPSDQDCEAILRALQGLTLHQARQVITQ
                     CVIEDGVLSADDVQTILTRKVQAIRDGGLLEYYPLEDNRFELGGFVKLKSWLERAKMG
                     FTAEAKALNLTPPRGIMLVGVPGCGKSLAAKAIAREWHLPLLKLDAGRLFDKFVGESE
                     KNFRKAIEMAESLSPIVLWIDEIEKAMSAGGGSGDADGGLSRRLFGAFLTWLQEKKQD
                     VFVVATANNLSALPPELLRKGRFDEIFFVDLPDKDERTAIWSIHLNLRKQDRAQFDLP
                     KLVDASKGFSGSEIEQAVVAGLYRALYHKQPLTTDLLIQELSHTVPLSVTRSEEINQL
                     RATAQGRFVNVR"
     gene            53806..54816
                     /locus_tag="PK063_03995"
     CDS             53806..54816
                     /locus_tag="PK063_03995"
                     /inference="COORDINATES: protein motif:HMM:NF018028.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HMZ96235.1"
                     /translation="MTPDLENSCKDEEARATPVATFWRRTGAAVADVLLLGAIGACLG
                     FLWFDQLAALGRTGRFIGAAIALVYFATLNSQIGQGQTLGKRLAKIRVTDAKGALISL
                     PRSAFRATIFFAPLALNGTATPPGPYEQLVGIVLSILIFGVGVAQAYLYCCNRRTGQA
                     LHDIVVGTFVREAESASEIQQKMWKPHLAIAGGLSTLVLGVLLLPYTSDPPDFVSQLA
                     EARRLAQSVVPDAHVSISRQTSMMTTPGSGQTPASRVQLSVEVRVKPENFESVADNIA
                     MAMFRSSSGVGDVGQVVIVISYGYDIIISHARTTKVFAHTPQEWLKRLKLDELHNVVP
                     PA"
     gene            complement(54918..55778)
                     /locus_tag="PK063_04000"
     CDS             complement(54918..55778)
                     /locus_tag="PK063_04000"
                     /inference="COORDINATES: protein motif:HMM:NF012451.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaJ domain-containing protein"
                     /protein_id="HMZ96236.1"
                     /translation="MQHQHNTNYYAILELSADATEADIKRAWHEQMQIWHPDRFLHSS
                     TLHKKAEARTQLINQAYQTLSDPTARARYDSGRQQPSAPPPPPRPSSPPRPQPVTRPR
                     QELRGPQTMLNVTRFSHPKIMVPAIHLLVDVHETQPYAFKGLIRIAGTRTQALPAGDY
                     AIAEAPGIFCVERRRAEEFNTIVSNPSDNRPRFLRELEPLLAIPHRFLVIEGALHSHR
                     GGGRLEQYHRNGLIDFLDSITARFGLQIIYADSRDEAEERVANLAAIHYAYYLAEQQG
                     LGRCLTENDA"
     gene            55947..56966
                     /gene="galE"
                     /locus_tag="PK063_04005"
     CDS             55947..56966
                     /gene="galE"
                     /locus_tag="PK063_04005"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HMZ96237.1"
                     /translation="MILVTGGAGYIGSHTCVELLNAGSAVTVFDNFSNSHPEALARVQ
                     RITGKSLRLIRGDIRDRAALVAALRESGATSVIHFAGLKAVGESVEKPLSYYDNNVVG
                     SLRLLEAMGECGVTTLVFSSSATVYGDPQRLPLTEDHPLSATNPYGRTKLMVEEILRD
                     LQRSHHSWRIGILRYFNPVGAHASGLIGEDPQGMPNNLLPFVAQVAVGRRDHLNVWGN
                     DYSTPDGTGVRDYIHVVDLALGHLKALKALDGWDRPKECLTVNLGTGNGYSVLEIVRA
                     FEKASGKAVPYKIAQRRPGDVASCYADPGYALKALGWQAARGLDDMCTDAWCWQYNNP
                     NGYTG"
     gene            56978..58195
                     /locus_tag="PK063_04010"
     CDS             56978..58195
                     /locus_tag="PK063_04010"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96238.1"
                     /translation="MMNRLTRDRAQTDLLTHRHRSVVWVLGAGALLSAFLFVPAAQAN
                     HRDHQPHADAEVPGVLGQGREIPGAPFKVFLSTGAVADVSGLDDADLDAAVQTVIDTF
                     IIMLQHRADYPRFEESLKKQALKQVVIEPVVVNDEGKAFPFLVARTKEPGRVTLLISA
                     TSLKDRGYLNHPDSLLPVLSREFQWVVSKADTAPKAKAVAVERNLEKAPILTDEEIAG
                     LSAEERVRLLQQLFDTYLRTVDDQRSLDGQPWYEVGHSAPLPPTHADSTTKLYDIRIR
                     EALQKIVRDPFFLERTPKAVRNLLNGKVWNVAYVKIDQRDWSTRTRVLSEEKSVVVGK
                     RERRIQPAAILVNVHRLAAADDPFYRETQGLPMGALSADQLAHVIALEIHHNIQEKSL
                     SGHTAQDALTAPR"
     gene            complement(58208..58876)
                     /locus_tag="PK063_04015"
     CDS             complement(58208..58876)
                     /locus_tag="PK063_04015"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96239.1"
                     /translation="MDRSQAGTVRSMSFACVGLTLVSLLTGALPAAALESSARTIVSQ
                     SNSHVGLSIDLAGFTIERDQLKPNGRRYLMASHPGTGIKVAIALEQVAGKASTAGCIE
                     HLQHVQKGSAVSRGKDVTLSTAHEMPTLEYTLPRFQGVRLDQKSLYACMAEGNVYANI
                     HVSKVRYTDADASRFRQLLTTLRLQSGPSPRMTAHQSNSAAPLFSVDTVRYEQKNEAR
                     TIAP"
     gene            59386..60447
                     /locus_tag="PK063_04020"
     CDS             59386..60447
                     /locus_tag="PK063_04020"
                     /inference="COORDINATES: protein motif:HMM:NF012931.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HMZ96240.1"
                     /translation="MGRSGMLLCAMVVMWAGLWEVGAAAEPSSVPAAEALRIMQFVLT
                     GTVSTERARGFVNEAQAAGFTAVQVLLTDGVQFDHAPWIPVKTAWTKAEFLSWADYAR
                     AHGLEVIPEVKLLTHQEQFFQRQYPGLMFNTVSYDPRKDATYAVVFPFLDELIEAVHP
                     RAIHIGHDEAFGWTVGQVSKWLKLGEVMIPADLFLRDVVRVHDYLGKKGVETWMWADM
                     VLSPAEFPGAQTRHLHGIAAGYGKALRQQLPRDIVMCDWHYGDEQGSFPSIDIMQGEG
                     FRVIGATWKQESATRKFSRYALSRHAYGLMATTGFHIQQNDTKMIHWIIQASGALFRN
                     PEAVVPPMPASAGSSEGRG"
     gene            60764..61855
                     /gene="ychF"
                     /locus_tag="PK063_04025"
     CDS             60764..61855
                     /gene="ychF"
                     /locus_tag="PK063_04025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003026825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HMZ96241.1"
                     /translation="MSVKCGIVGLPNVGKSTLFNALTKSGIAAENYPFCTIEPNIGIV
                     EVPDARMQALADIVKPQRMQYATTEFVDIAGLVAGASKGEGLGNQFLANIRETDGIVN
                     VVRCFEDDNVVHVAGKVDPISDIATIVTELALADLTTVEKAQERNVKLIRSGDKDAAK
                     LGDLLVQVAACLNEGKPARTMKLDPAQRALLKPLCLLTMKPVMYVANVSEKGFANNPL
                     LTRVEDYAAQEGAPVVAICAALESEIAVLSDEEKQEFLADIGMKEPGLNRLIRAAYQL
                     LGLQTYFTAGVKEVRAWTIHIGDTAPQAAGVIHGDFEKGFIRAEVIGYDDYIACKGEA
                     GAKEKGKMRLEGKEYVVRDGDVMHFRFNV"
     gene            61910..62368
                     /locus_tag="PK063_04030"
     CDS             61910..62368
                     /locus_tag="PK063_04030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HMZ96242.1"
                     /translation="MMNEQDTQRAVAILNRIMELELAGVVRYTHYALMIYGYNRIPIV
                     SWLKGNADESLAHAHKAGELVTLLGGHPSLKIGTLLETEKHDIGDILRESLEHEKAAV
                     ASYYELLKLAEGKSVLLEEFAREMIVGEELHLDEVNKMLRKSGDVQAFRS"
     gene            62466..62930
                     /gene="trmL"
                     /locus_tag="PK063_04035"
     CDS             62466..62930
                     /gene="trmL"
                     /locus_tag="PK063_04035"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HMZ96243.1"
                     /translation="MFDVILYQPEIPPNTGNIIRLCANTGARLHLVKPLGFTLEDKQL
                     LRAGLDYHEFATLAVHETWETCLQRFTGQRLFAVSTKGRQRYDLVQYAEGDAFVFGPE
                     SRGLPAEILASVSDQQRIRVPMVPGSRSLNLSNSVAVVLYEAWRQAEFGQCL"
     gene            complement(62999..64882)
                     /locus_tag="PK063_04040"
     CDS             complement(62999..64882)
                     /locus_tag="PK063_04040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HMZ96244.1"
                     /translation="MQKHLQTSSASASLTVAAMGVVYGDIGTSPLYALRECFHESHGL
                     AVTPENVLGILSLIVWSLVLVVTVKYLLFVMKADNDGEGGMLALMALSQRSHPVNLRK
                     GLSLVVSLGLVGVAFLYSDGIITPAISVLSAVEGLTLATDLFTPYVLPITVGLVALLF
                     TIQRRGSGALGSVFGPIMLVWFAALALLGLHSLIQTPAVLLAANPLYAATFLLRHAGI
                     GFLVLGSVFLVLTGAEALYADMGHFGRRPIQLGWFAVALPALLLQYFGQGALLMRNPA
                     ALANPFYHLAPDWMLYPLIALATVATIIASQAMLSGAFSLTLQAVQLGYLPPLRITHT
                     SAEQHGQIYFALLNWLMFIGTVGLILSFGSSTNLAAAYGIAVSGSMIITTLLMYRVTR
                     SHLGWSALPALMAVGTFLCIDLAFFLANAQKIPHGGWFPLLLGAAIFTVMSTWARGRA
                     IVAEHLRVQFPPLHQFVGDVLSKVEYRTAGQAVFLSQHPDITPPALLQNVRHNKTLHE
                     HVYLLTVRTEHVPFVPAGAPLEITPVYEGLFQVIARCGFMETPDIPRVLTQLAANGHV
                     LPLQNTTFFLSRITFLATPKPGMAIWREKLFVVLSRNTQRASSYFHLPSEQVVEIGLV
                     LEI"
     gene            65161..67554
                     /locus_tag="PK063_04045"
     CDS             65161..67554
                     /locus_tag="PK063_04045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HMZ96245.1"
                     /translation="MTASTTPTISAEAQQRIVDLLAKELGVASPQVSAAVTLLDGGAT
                     VPFIARYRKEATNNLDDTHLRTLEERLLYLRELEERRQTILASIEEQGKLTDELRRAI
                     EQAATKQAVEDIYLPFKPKRRTKAQIAREAGLEPLADALLADPTLDPEQEAVKYVKVV
                     AAAEGVEAINVPDAKAALEGARDILVERFAETADLLALLRTKLWNEGIVTSTVLPGKE
                     TAEEEKFRDYYAYSETIRTIPSHRALAMFRGRTLGVLKLDLGLGETLDAQVPHPCAAL
                     IAAHFGIENKGRRADKWLSDVCYWAWRVKVHLHLSTELLLQVREAAEAEAIKIFGRNL
                     HELLLAAPAGPKAVLGLDPGIRTGCKVAVVDATGKLLDTTTIYPHQPRNDWQGALATL
                     VDLVIRHGVELISIGNGTASRETDKLAIEVIKVVTERKPEQKVAKIVVSEAGASVYSA
                     SAFAAAEFPTLDVSLRGAVSIARRLQDPLAELVKIDPKSIGVGQYQHDVNQRALARSL
                     DATVEDCVNAVGVDVNTASAPLLARVSGLNRVLAQNIVEYRDTHGPFPNRTMIRKVPR
                     LGEKTFEQAAGFLRINNGDNPLDRSAVHPEAYPVVERMLARLNKGIAEVMGKPTVLKD
                     LSPADFTNETFGLPTVRDILTELEKPGRDPRPEFKTATFRDGVESLADLQPGMVLEGV
                     VTNVAAFGAFVDIGVHQDGLVHVSALANKFVKDPHEVVKPGQIVKVKVLSVDVARQRI
                     SLTMRMDDAATAAGQPDLRAGAVREGRDRRQDAPRPASQPQPTSAFALAMARAQQKK"
     gene            complement(67596..68198)
                     /locus_tag="PK063_04050"
     CDS             complement(67596..68198)
                     /locus_tag="PK063_04050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HMZ96246.1"
                     /translation="MRGPGSSGEQQAQARFGTSDRAAAFYEHQVLASLNQPMREFIAR
                     MEMMHIATADAGGKCDCSFRAGTPGFVQVLDDKTLAYPEYRGNGVLSSVGNILENPHI
                     GLIFLDYYQTTIGLHVNGTARVMDAQEIATLPNITSGMREAAHSKGGRQPKAWIVVGV
                     EEAYIHCSKHVPLLARREKQIVWGTDDERLKGGNFFKITP"
     gene            complement(68303..>69663)
                     /locus_tag="PK063_04055"
     CDS             complement(68303..>69663)
                     /locus_tag="PK063_04055"
                     /inference="COORDINATES: protein motif:HMM:NF025885.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ96247.1"
                     /translation="MSSERIRTLIIDDEEFVRLVVEQALREEGCDTRIARGGQEGLDA
                     LRTGDFDCVITDLRMPGVDGRAVLRWVKDHQPDVDVIVLTGHGDVKDAVAAIKDGAWD
                     FLIKDTPFDGTAVKAALAKLRTVRELRRENLAARHGGYRQEALVKGISNAWQTLETQI
                     AQVAPSQAPVLIQGETGSGKEVVARLLHAQSHRAQGPCIAVNCGAVSRELLESELFGY
                     EKGAFTGATTAKPGLIAAAEGGSLFLDEVGEMPGPMQVSLLRFLDRNEYRPVGSTRTL
                     RADVRIICATNRDLQELVFQGRFRDDLLYRINTVTLRVPPLRERPEDIPGLVEHILHN
                     LRLPGTTARTPTPEGLAHLASYRWPGNVRELRNVIERLVLMSPQTGPITGEEVLQVLP
                     RSSTTSVSEEQSQLPLEEIERRHIERVLQACGGNKTKTAHTLQIDYKTLLAKLKKYEA
                     GH"
BASE COUNT        14355 a        18999 c        21318 g        14991 t
ORIGIN      
        1 ggatggcttc atctattgaa gatggcggcg atgcgtcccg cttggccgcc attctgttgg
       61 atcgttgctt acaaaggtag agaagagaaa aggaatactg gagccatggg cagattagga
      121 acgcaaagac tccgcccaac gaggccgccc ggccgttccg gaccactgga ccggacggcc
      181 ggggggatcg ggggcgcagc ccccgcttca cttgatctat atggtcaaag taggatcaga
      241 ctctcgcaac tagacatcgc atgaatttga agctattcta cgtactcacc ctcgtatgtc
      301 agtccacccc aagatgcgtc gggtggcccc aatcttggac ttatgactgc agaaggaagg
      361 agtgttctca acgtggcgga caaatcgatg gaggaggatg actaccgcgt agaggcacag
      421 gcgacgggta agaggcagga acagatcgag aaggaaaagg aagacctgtt agcccggatg
      481 gggtcgtccg atatctcaac tatgcgccat cgagtcgcat gggtcctaaa tcactttcct
      541 agcactcgaa attccgatat cgcactgcag attaaatact gggaatgctt tgacagcgaa
      601 ctgtatcgag gtagccctat tgaagttgat gatctgtata ggttgacccg cttaacttca
      661 gtagcgaggg agcgtgcaag aattcagaat caataccgat tgttcttggc tgatgaggat
      721 gtgcagcagc gacgaggaac acttgaagat gaggaacggg aaaaggcaat cgaaataccg
      781 gactgtcctg tatataaggt ctatctcgac gaaagtggca agactacgaa ccatttaatt
      841 gtcggtagcc tttggttttt gtcgagcgga acagaaggtt tcgaacttta tcgacaatca
      901 aaagatctta aagacaagca cgattttcaa cacgaatttc atttttcgca aatgaagaaa
      961 gacgagcttg ttgtatacaa ggaattggtc gatatctttt taacccaagg cggcacgatc
     1021 agctttaagt ctatttcagt tccaagagct gggattaaga atgtttcgga tgctctcggc
     1081 gacctgtact acctcctgtt aacaaaaggg gttgagcagg aaaattcaac cggaagggct
     1141 ccattaccaa gaattcttca agtttggaaa gacgctgagg agattggtag cgataagatc
     1201 ttgatggcga atctggctga cagaataaaa cagacctcag cgagtttata tgaaaacaaa
     1261 ctcttcgttc aggaatttgt cgctgcggat tcgaaaagca gtatattttt acaagttgcg
     1321 gacctcatgg cgagcagtgt taatagaata ctttgtcgag gagaacaacc acgcaatcag
     1381 aaggacgaac ttgctgacta tttggtgcaa cgcctcggaa tatcaactac tcctgatctt
     1441 gaagttctta tgggtgatat agctgctcac atccgattgt aattctccaa tactcatgct
     1501 tcggtagcat aatgccgttt tgagaggcat gctgaatagt cgctgtattt tggctagcaa
     1561 ctcgaatgga aaaaagccgt ctccagttca ttcgcctacg agccatcttt ccccctgaag
     1621 attctctagc tgtcacgatt gctcgattat gcattctccg cgaggatctc ctactcgagg
     1681 cccaagcgat aaggcaggaa acattaggag ccttagatag caatgggccc gagtggcggc
     1741 gtctgtattt ttggagaaat tcattcagaa ctcttgaaag cgtgagaagc gctctccacg
     1801 tccttagctc taacggggaa ttcaagaagg ctctaaaaaa aagaacctat cgaaattcaa
     1861 aaaggtttcg atcgattaac aaaagcgttg agaaaagttt cagcagattt cctgaagact
     1921 ttgcgtgatg accttggagg ccacgttttg gaagcacggg tcaaggaagc gttagaaaga
     1981 atggattcat ggcagatggg acttatcgaa gttagcaatg gcgtattggg gaaacagcat
     2041 tataggttta catccgagct cgtattgcag atgatgttgc cggccaaatc tatagatagg
     2101 ccggaacgtg agctcaaacg gagaagtcga aaaggcagta ttttaatgtg ggctgtgctt
     2161 gcgatcgacg agatttttaa cggatacgtc aattccaggg aattattatg aaaagtgtgc
     2221 ttagggcaat cgagataagc gtgtgaagct cgttctggta gggataaacc atttcgatcc
     2281 tctgtgtaag gaaagcctcg caaggacttt gatagagctg cgcaattgtt acgggctacc
     2341 gccagctttt gtagccgtgg aatgggatga aagtctcttt tctaaagtgt gcgctcaaag
     2401 ggccgcattc agagaaaagt gcagacttga atggccagac gcaggagaag aaacactcaa
     2461 ggttcttgag gcttcgttag ggtttgaggg agatacccac cgggaagtgt ttggggatct
     2521 tcaaactctg tggctagacc aagggcgtca agggaatgtg gagaactacg cttcacaacg
     2581 ctttgtgatg tataaggatt ttttacggga gaaaaccaat aaggattgtc ccactatgct
     2641 gtcgaaattg agtgttgtag ctagacatcg acagggccga ctggatgcgg ggactcagcg
     2701 cgatcaaaaa tgggaagaat tgctcttaga aagattatcg aaaggtccag gtttgtgggc
     2761 gatttgtgtg ataggggcgg gccatatagc caatattcca ggcggaatac ggacgcgcct
     2821 ggaggctaag ggacagcagt gcgaaattgt caatctatga accctataat ttatcactca
     2881 gcgctctgac gtccttctgc acatgtatat tagatttgat accaacgtgt tcgctcagac
     2941 agcaatatgt aagaagtgca atctaccctg ctcaggaatt ggctggtgca tcgcatttaa
     3001 tgcaaactca atcgtctgcc ctggatacaa ttcgtggagc tgtcatggaa ctgtttgaag
     3061 aattcgtctt ggcgtattta acaaaggaca agcacgtctt tgtcaaccct caatactcca
     3121 tacgagatga agtaagtggc ggcgaatgga gttgcccaga ttttctcgtt ttaaatttta
     3181 aggacaaaaa agtatctgtg gtagaggtct ctaccggata tgatcttaag aacctcgtcg
     3241 agaaagtgaa caatcgagag atccactggt ttaataagct taaaaagcaa ctcgtgagga
     3301 gtggcgttat cgacaatgac tctcattggg actttgccat ccaagtcttt atacgaaaag
     3361 aacgagacaa attcttcagg caaacaattc attcacacga tagggttgaa gtaatgtctt
     3421 tggaggatct aggttttcca tggagtaagt cgtggcatgt tgagcagcat aatgatacgt
     3481 catcatcaaa gcattgatgg aactgggaaa ggatgctgag attcagtgca gggcacgacg
     3541 acgaacatga aactgcaccg ttcgatttga atacagaccg tggactaatg tttaggaaag
     3601 caatattaat cgccgcgatt tttatgcttg gagttgatca cctattggct ggcgggcaag
     3661 attttgacgc cgcgagcttt tcgaccgttc tagagccctc ttcaaatgac tatagtttgg
     3721 aagagcaacg ggtcacatct atggcactca gcccaagtga aggattactt gccacgggag
     3781 atttggatgg caccttgaag atttgggatg ttcaaacgtg caaactgctt aagattcttc
     3841 tggttaaaga atctgaagac cctcgattgt cggatggaat tggcatcact tccttaacgt
     3901 tcagtccaga cggacgctgg ttggccggag gcagccgtga ccgggtcatc cgaatctgga
     3961 aggtagcacc gcttccttcc atccaggaaa cttataaagt tagtggtcat caaggggctg
     4021 tgagatctct cgcatatagt caggatggtc gatacctcgc ttcggtcggt ggtgggacga
     4081 ttcgtacctg gaagatcgac gggcaagtaa cagaaatggc ggttttcccc accgacaacc
     4141 tgcacgattt tgctgttctc ctgagccgag atggacaaac actattctct ggaggacacg
     4201 aaaatgtggt ccgtgtctgg gaccttaaga ccggaacgat aacacgctcc ctaaatgtac
     4261 cgggcagagt cagagcccta gccttatcac cagatgacag gatggttgcg gcagcactag
     4321 aggcaaaggg acccgaatgg acggggatca gcattaaggt ttggaattcc caatcgagtc
     4381 aactgatgct cgatttagag gcacatggcg agtctgcgtt atccgtcgcg ttcagcccgg
     4441 atgggcagcg catagcttct ggtggcgccg atgggaacgc acatgtttgg aacgtgaaca
     4501 caaaaacgct gctccagaca atgagtccaa tttcagaaga gaaacccagg aagtggtttg
     4561 atcaagaaac gacaacgtta gctggaggca ctattcaaac ggtgaagttt ggaggtgatg
     4621 gccgacggtt attcacagcg gggtatggct atccaccgag agtatgggac gtaaattcag
     4681 ggaaggttct aaaaatattc agagggcaag ggtgctcctg atcatcgtga cgtacatctt
     4741 tatgaatggt tgtgttcatt ggcttggtat caggcaccaa gctaagtgat ggcgcggctt
     4801 aacaggaaac atttctagac atatggaatt gaagcgtgcg actagaataa gggccgtgga
     4861 gccgttccgt acttcaagtt agagattgtc ttcctcatct aagtattttc ttggtcacgg
     4921 ttttggtcac ggttccagat caaatttggt cataaatggt cgtaaccggc ttggtgccga
     4981 gatgaccagt ttttctttat atttcatagg ctagcgctaa aaatcgcact cagtcgcaaa
     5041 ctaggccttt cgaataagta catcgcctgt gatgcgacgg tattcgcgca gaaggcgaaa
     5101 gggtaggttc tcagacgtcg agaagcccct tcccccagct tcttgacaag acatggtttg
     5161 cggccgatat ccattaatca ctgtcgtttt ttttcgtgcg gcttcataag atgaagcgcc
     5221 gctgacttac gatcagagct ctgggtgggg ttgaagcgaa ctcgccctgt taccttccct
     5281 ccattgcagc gcccgtttta acaggggaat cgtcccttgg taagccaaga tcgctgaggg
     5341 aatggccaag aacaagccaa tgagcgcaag cgtaatcgtt ttatcccaaa atggcctggc
     5401 catgaatcga tcggttcccg cacaggccca gacaatccaa gcaaagatgg ccccgctcat
     5461 gactagaagc ccacgattca ccgctggcga aatgaatgtc gtgggatcga atggcttgaa
     5521 tttgaggctt ggtcccttgg ccgtcaccag aatacgaccg gcttcatttc ccgtcatcaa
     5581 gagacgaacc atcagtttgt cccctgggtt catgagggga atgcggacct catgcgaatc
     5641 agcctggcgg gcctcgattt taggcccgat cgccaaagca gacgacgaac agtgcgcatg
     5701 caggacggtg actccggcgg gaaatgtgag gtgaaccgat tgctcttcaa tatccttcat
     5761 ccccaggttt tgaatgacca gccccatgat ccgacatccg ttcagattct tgccatcgag
     5821 tgacattgag agtcgcccgt caaggtctgg atgtcggagg ttgatcatcg gttcgttttg
     5881 ggtaagggca tagcctaaaa ccttcttttg cgagccgatc aaatacatga tcaacggtgg
     5941 tatcagaccg gtaagaattg ctccggcata agcgagccaa ttgggcatca catcctcctc
     6001 gcaagtgtta caggaagtat agcttccacc atggaaaccg caattcagac ccctggtagg
     6061 accgtctgcc tcgaaaacat tcttcgcggt taatccccgt tcttttaatt gcctggaagc
     6121 tagttgagtt ttctttctat gatcctgtcc tccgtatctc gagcatgtgt gcatcctccg
     6181 cgcggtgcgt catgcccgat cgattttcca gcataagacc ccttcagcca ctaacaccct
     6241 aggctttcgg gttcgacgac tatctcttat cgaggggggc actagggatt gttctagtcc
     6301 gctcggtttt tctccacgct atactgcgga taaattttcg gaagaatttt catatggccg
     6361 tgattgatca ctcacccttt tgaggctgga ccatgactga tccaaccagg caggccgata
     6421 gtcgctgtga aacgggcata gacggactga acgaaatcct tggcgacgga ctaccggcca
     6481 actgcatgta tttagtgcag ggagacccgg gctcgggcaa gaccacgctt gcgctccagt
     6541 ttcttctgga aggcgtgcgc ttgggggaaa aaaccctcta tatcaccctc tccgagacga
     6601 aagaagagct ggtcacggtt gcccgttcgc atggctggtc gctggactcc atttcgctct
     6661 tcgaactctc ggccatcgat tcgcttgtac ggcctgaggc acggacgacg gtgtttcacc
     6721 cttcggaagt cgagctcacc aaagtcagcg aaatgctgca gtcggaaatc cggcgtattc
     6781 aacctgcgcg cgtggtattc gactcgctgt cggagtttcg cttgatggct gaaaccgcgt
     6841 tacggtatcg gcggcagctg atcaacctca aacaagaact ggcgaaatac aactgcactg
     6901 cactgctgct ggatgacagg atggacaata gccggatcgg tggagatccc catgtcctca
     6961 gcctcaccca tggcgtgatc gaaatggagc agttgtcgcc cgattacggc cggtcccggc
     7021 gaaggttgcg tgtcctcaag atgcgtggaa tgaaattccg cgaaggctac cacgattaca
     7081 gtattgagaa ggggggcctg cgagtgttcc cccggattct tgcctccgat catcgggctg
     7141 atttttcgcc ccaggcggtc tcgagcggca accaggagtt tgacgagctt ctcgggggcg
     7201 ggctcgatcg tggaaccacc acgctcatca tgggtccggc cggaacggga aagtccacgc
     7261 tggccatgca gtatgcagca caaatggcgc aacgaaatga atcgagcgtc ctgtttgcat
     7321 tcgatgaaat tcgaggcatt gtgctggcgc gcgcgactgc tgtcgggtta gatgtcgagc
     7381 ggcatatcaa cacgggtctc atcgatgtgc agcaggtgga tcccgccgaa ctttctcccg
     7441 gcgaattcgg catgcgcatc cgcgaggctg tggagggtgg ctgtaccctc ctgatcatcg
     7501 acagtctgaa tggatatttg aatgcgatgc ctggtgaaaa gtatctcgtc aaccagctcc
     7561 acgaaatgtc cgcctatctc aaccagaaag gcgtcgtcac catccttatt ttggcccaat
     7621 acgggctcat cgggcaggcc gaggctccgt taaatctgag ctatctcgct gacacggtcg
     7681 tgagcgtgcg attttttgag gcagccggcg cagttcggca ggcgttgtcg gtgatcaaga
     7741 agcgaagcgg ggggcatgaa aaaaccatca gagaatatca attggtgtca gacggcgggt
     7801 tgcgtatcgg cccacccctg aagcaatttc aaggtgtcct gacggggacc ccttccttct
     7861 acggcgccct cgaacaggtc atggagcgcc ctgatggtgc gaactaggct tgaggagcgc
     7921 atcatcatcc tcgcccccat cggtcaggac gctccggcca tggcaagggt gctcatctcg
     7981 caaggtgtgg atgcgatcgt ctgcgcaacg gctctggaca cctgtcgtga gctggctgtg
     8041 ggtggcgccg tcctgctcgt gacggaagaa tccctcgagc tgcctcatat ttcccagttg
     8101 ctccaccatc tcaaggcgca gccgccgtgg agcgaattgc cgatgattgt gttgacgcga
     8161 ggcggagaat cccgcttggc acgtctcctc gatctggtcg ccgaggcagc cggcagcatt
     8221 acgttgctcg aacggcccat tggcgaggcg acgttgatgc gctccatcga agtcggattg
     8281 cgatcgcggc ggcgtcaata tcaggtgcgt gatcttttgg agcaagagac actgtcgcaa
     8341 cagcaactgc gggaatccga acagcaatat cggacgctgt tcgaatccat cgatcagggc
     8401 ttctgcacga tagaagtgct gtttgacgag cagcaggagc ctgtcgacta ccgcttcctg
     8461 ctcgtcaacc cggcgtttgc cgtgcaaaca gggctccgcg atgtggtggg ccgccacatg
     8521 cgggatatcg tgccacaaca tgaagagcat tggttccgga tttacgggaa catcgccacg
     8581 actggtgagc cattgcggtt cgagaaggag gcgaaggcgc tggatcgcca ttacgagata
     8641 tatgcctggc gcatcggcct gccgtccgag caaaaggtcg cggtcctctt caacgatatc
     8701 acgcaacgga aggcttcgca gttccgcttg gagcaattcg cggaggagct tgaacgcaag
     8761 gtctccgagc gcacgtatga actggtggct tcgcaacaac agctccgggc gttggccacg
     8821 gagctcaatt tggccgaaca gcgggagcgc acacggctgg ccgccgagct tcatgatcat
     8881 ttggcgcaaa tgctggtgct ggttcggctg agattaggcc aggccaaagt cggccctttg
     8941 tctcattcca tccaaatgat caaacaggct gaagacgtcg tcgacgaatc cctgacctat
     9001 acgcgcaatc tcgttgcgga actcagtccg cctgttcttc atgagttcgg gctctttgtc
     9061 gccctccgct ggctgggcga acagatgcgc cggtatcact tggaggtcag cgtccgtatc
     9121 gacacgccgg aagaattgaa attgcccgag aatcaggccg tgctcgtttt tcaatcggtt
     9181 cgagagttac ttctcaacgc agtgaaacac gccgggtcca agaaagcgtg gatcgcggca
     9241 gccagtgaag atggagtgct cagcatcgtc gtggaggatc ggggggtggg gtttgatccc
     9301 atcacgttgt cgtcacaaaa actcgccgcg atgtcgtcca agtttggcct attcagtatt
     9361 cgccaacgta tggaagcatt gggcggccgc ttggagctgc gttcaaaact cggcgaagga
     9421 accaaagcca cgctggtgtt gccgatcacg cagctttcgg agcaggcgac tgggatctca
     9481 ttgtcctaca ttgcaccgtc cgcgcatgtc gcgcgcgcac ccagcaccgg tcattgcaag
     9541 tccgttccct atcgggtcct ggtggcggat gatcatgcca tggtgcggca ggggctctgt
     9601 ctgatgctgg atgcctgtcc ggatattgag gtgattgctg aggctgccaa tgggcaggaa
     9661 gcgctggagt tagcgcggag attgaagccg tcggtggtgg tgatcgatat caatatgccg
     9721 ctgatgaacg ggatcgaagc cactgcgcag atacgaaccg cccttccgga caccatcgtc
     9781 attggtatgt cggtgaatgc ttcagtagac aatcaggagg ccatgcgaac cgcgggggcg
     9841 tcagtcctgc tcccgaagga agccgccggt gatcaactgt acggcgccat tcaatctgcg
     9901 atgaaggggc tatccgaaca tacgggcccg ttgatccgat cacaggagac acggctgtag
     9961 actcccggtt cttgggttca ttgacctcct tccaggggat tttcctagtc tctccctacc
    10021 tagtttccca gtaccttgtg agacatctca ctgaaaggag tcctccatgc ctaacatcgt
    10081 cctggttatt ctcattctgt tgcttgtggg tgtcctgccg acatggccgt atagcagtgg
    10141 gtgggggtac tatccttcag gcggactggg gcttctcctc ctcatcgtgc tcgtcattgc
    10201 cttgagcggt cgacgaggag cgttgagaag ttaggcgaag caggctgcct gcgcgtggat
    10261 acatccggac tgtgagtaat cagcgccggt cgacggaggg cagaggaatc tcgttgcttt
    10321 tggagcacgg cccctgaatg gttcggttag caggatgtag gagttcatca ttatgacaga
    10381 agtgctcgaa gggcgcccca cgcctcgggg tgccacatgg gacggacagg ggaccaattt
    10441 cagtctgttt tccgcccacg cgacgaaagt tgagttgtgc ctcttcgacc caacgggaga
    10501 aaaagaaatc gaccgcgtgt cgttgcctga atacaccgat cagatctggc atggatacct
    10561 ggccgggatc caccctggga cgccttatgg ctatcgtgtc cacggtccct atgaccctga
    10621 cgccggtcat cgctttaatc cgaacaagct gctgctggat ccctacgcct atgcccacat
    10681 gggcgaactg cagtggaatc cggctctgtt tggctatcaa atggagtccg gcgatgatcg
    10741 aacatttgat gaacgtgaca gtgcgccatt tatgccgaag tgcaccgtag tcgatcaaaa
    10801 cttcgattgg tcaggacctc gagatcggcg tacgattccg tgggatgaca ccgttgtgta
    10861 cgaaatgcat gtgcgtgggt tcacgaaact tcatccggcc gtgccgtcca ctctccaagg
    10921 tacctacgag gggctcgcga cgaaggaggt tctggactat ctgcagtcgc tgggggtcac
    10981 atctatagag cttctgccga tccatacgtt tgtcaatgac agtcatctcc ttgagaaggg
    11041 gctgaccaat tattgggggt ataacagtat tggatttttc gcgccggatc cgcggtatgc
    11101 cgcgaatcga ccggaaagtg ttcgcgaatg caaagagatg attgcgcggc tgcatgatgc
    11161 cggtttcgag gtgattctgg acgtcgtcta caatcacacc gccgaaggca atgagctcgg
    11221 tcccacgcta tcctttaaag ggatcgacaa ctcaagttat taccgcctcc agcctgagca
    11281 accacgctat tacattaacg atacagggac ggggaacact ttgaatctga gtcatccccg
    11341 cgtcattcaa ttagtcaccg atagtctgcg ctatgccgtc caacaaatgc acgtggatgg
    11401 attccgtttt gatctcggga ccattcttgc gcgcgagccg aatggatttg ataatcgaag
    11461 cggcttcttg aaagtctgta gtcaggaccc cttgctggct accgtgaagc tgattgccga
    11521 gccctgggac tgcgggcctg ggggatatca agtgggggga tttcctccgg ggtgggctga
    11581 gtggaacgat aaatttcggg atgatgtgcg cgatttctgg cgcggcgaac tcgctgctac
    11641 caatcttgcg gatcgactct gcgcatccgc ctccgtcttc aatcatcaag gccggcggcc
    11701 ctggtcgtgc gtcaactttg tgacggcgca cgacggcttt acgctacatg atgtggtggc
    11761 cttcaacgag aagcataacg aggcgaacgg ggaggataac caggacgggt cctctaacaa
    11821 tcgctcatgg aattgtggcg ccgagggacc gacggaagat gcttcaatca acgcgcttcg
    11881 tgaccggcaa atgcgaaatc tcatggcgac gttattgatt tctcaaggga cgcccatggt
    11941 gttggcgggc gatgaatttg gccgcaccca acggggtaat aacaatgcct actgtcagga
    12001 caacgagatt agttgggtcg attggtcgtt gctcgaaaca cgatcatcgc tctttcaatt
    12061 cgtcaaagaa ctgattgcgt tccgtcatca ttatccgatt ttacgccgca atctcttttt
    12121 gaccggacag ctggccgagg attccggcgt tcgagatgtg acctggatca atgccaacgg
    12181 cgggccgatg gaagagcatc actggaccga tacgacgatc cactgttttg gaatgctctt
    12241 ggacggccgg gcgccgacaa ccggacgtcg acaaccgggg aaggatgtca cggtactggt
    12301 cctgatcaat ggccaccatg agccggtcca gtttaccttg cccccttgtg tcggtgcgtc
    12361 agaatggaca ctgctgcttg ataccaatct gccggatcgc cctcagaacc aaaccttcca
    12421 gatgggaacc caatacctgc tcacggatcg ttcgctggtg ttattggtat taggagccaa
    12481 gcgaacggaa gagatcattc cggtatagcg ggcccacgtc gcggcaatcc atgcgaggca
    12541 caggtaagag aaatggcctg atgcgacggc agaagagttt cgtgtgtcgg ggaaggaacg
    12601 tcaggtggtg aatcgcctcc acgcaggagg acatctctct tacactcggt ctccgacagg
    12661 atcccagtcg tggtctcgct cgacggcgcc gatgagacgt tcaaagacat ccgggatggc
    12721 tccggtgacg cggctccagt tggaaatcat gggcacgccg agcgggtctt ccagaaatgc
    12781 ttcggtcgcg atcttcatgc ctttcagaaa gacctctacg gccatccgct cagcgtggcg
    12841 gtcgaactgc aagctattga tggccgcgtc gttttggtat cgcgtgatgg cttcctgggc
    12901 cgactgaaga tacgtggcgc gtaaggtctt gagcacgccc tccgacaaca ccacaccctc
    12961 gctggcgaga ttccggaaca gcgacttggt gatatccacg cacattttct gcaagccctg
    13021 ttcggcatta tccgcggaca gaccctggtg tttgtgttcg taggcgtcgg cgatatccgc
    13081 ctggcaaatc cgcctgagcg cgcaattgcg atagatttca gacagcacgc cgacttccag
    13141 cccccaatcg ccgggcacac ggttgatcca ggccaagtcg cgcaccatgg caaattcccc
    13201 cgccagcggg taacggaaac tgtcgaggaa ggtgagcaga gggtgagccc cggccacttg
    13261 ctggaggctt cgaatcagcg gcgtgaaata cagtcgtgtc acgcggccgt gaaggcgatt
    13321 ggtcacccgg ctgtagtaac ctttgcagaa ttcgtagccg agattggtgt tgacgatcgg
    13381 gtagcagagt ctggccaggt attcgcggtt gtagctgaga atgtcgcagt cgtgcagcgc
    13441 gatcacattg ctttcccccc gggccaggac atacccgaag gccatccagc atccccggcc
    13501 ttttccctgc aacccggtgt cgagttcggc ttgggccagc aatttcaaga tgtcctggat
    13561 accggctccg tcgttccaga cgattcgcac tcgttgcggc agcacggaaa aaaactgttt
    13621 ggccagccgg aattccagtg ccgatgcgcg atccagcgag atgacgattt cattgacgta
    13681 ccggatgtct ttcaacacct ggacgatatg tttcagcgca gggttttcca gttcggaata
    13741 aagggagggg aggacgaggg cgatcgggtt cgatgccgcg tgccgctcca actccttttc
    13801 caattgctca aggttggagc cgccgaggcg gtgcaacacg gtcacgagac cgttctgatg
    13861 aaaatccgac atggtccctc ctgtgcgggg cggggagagg gtggctgtat tcgtttatgc
    13921 ccggtgcggt agggaatgat tccatcactg gaggcaaaca ccaaccgtgc cgagcgggtg
    13981 aatgtgctga gaggagatcg ccgttactgc gccgggggca tagccttgct cgtcacgacc
    14041 gacttcacga tcttggctcg tttcacagac tccagaaagc gatccggagg ctcgggattg
    14101 ggcagattca cttcgacgga ataccacccc gacttcatcg gccctttctt gatcccgtta
    14161 agttcctgga ccagatcttc aatgcttttt tcggtggtgc cgtcctgaaa agccacccag
    14221 aacatgaagg cctggcgatc tgcgtcgcga aggttgtccg acaccgcgac tgcggtcggc
    14281 gcaggggtct ccttcggcgg ctcgtttttc gcgacgacga cgggcttgga tgccgcattg
    14341 gctttggcga cttccaatga ggtcaaggcc agacgggcat gcaactcccg attgcggctc
    14401 tccagcaacg cgacctgttt gaccagcgtt tcattgaccg acttcaccgc ttgaagatcc
    14461 tgtcgcacga gctcgcggtc ggcttcgacc gcagtcacgg ccacgcgcat gccggtttgc
    14521 acttcctgcg caacatccgt tttcacggtc ttgaggtctt cctgaacggc gacgacttgg
    14581 gtgctaaggc gctgctgcgt atgggcgacg gtgtcgatga gggtatttaa ttgcgcaatg
    14641 cgatcctgct cggcgcgcga cacggccacc gctgccgctt gtgactcgac cagctgggcg
    14701 agctgctggt ggacgtgatc gatctgatcc tgcgtcgatt gtcgcgcagc taattcttct
    14761 tccaactgat gggcacgatc ttctgagccc acccaggccg gaatccgttc agccaacaga
    14821 gcgaccacgc ccacggccag gacgacctgc gcgaaggcgg tggtcatgct ccacacgggg
    14881 ctgccttgcg tcgaggctac ggcggcgccg gcgggcaagc caatggctgt ggccagatgt
    14941 gaccaccaac ccggcgcgac ctcgtactgc acgttgagcg aaccgccgtc gaaatggttt
    15001 tgaacatgga gcgtgaggct gcctttgccg accgggatcc gcacgctttt ctggccggct
    15061 tcgggtgcca cgcaccctcc gatcagcacg cccgactcgc ttcggagttc caggtgttga
    15121 atgctgcgtt cgcgggctgt ataggcgaag gatggatcgg tctgtgagca attcaatgtg
    15181 ccgatgcgct cgtgattgac caggacctgg agaaacccag ggcgttcttc cgccgcgcgg
    15241 cgcggctggt catccagcgc gtcaagcaga tgtgcgcgat agtcgttgag ctctggtgtt
    15301 tccatggtgc cgtcctcccc gatcgcctcc aaagagagcc aggacgcctc cctttttcag
    15361 cggatgtata tggagattga cttgcggctt caccccgctg ctgacgtcgg cttgccggcg
    15421 atctgcgact tccagaaagc aatcgcggca aaacgccagg tgccagacgc ggtagtcgtg
    15481 gccgtagtca tcgtgaaaaa gttgccccca cttctgttcg gacaagcagg gataatgttc
    15541 cggttcgctc tttcgataat gcgattgcaa gacgggcatc agccgatcca cttcgttatt
    15601 gaggtggtcc ggtctcgtgc gcaattcttg ctccaaaatt tcgatttccg ggccactcaa
    15661 tcccgtttcg ttcatcgtgc gctgccagcc cgattggcgc caccgctcga agttcttata
    15721 gacgcgctgg ctttccgcct ggccgaaacc cagcagcttc accacatggg cctggctgaa
    15781 cccgtagaag tgataaaaca gcgcgatcag cgcatcgcgg ctcacgacgg cgcgggaagc
    15841 caacccatcg agaaaccgcc ccaccggcgt cagcaactcc ttgtggtagc acaggggatc
    15901 tggctggctg aacgatttcg cgatcaggct atccaacaga aaaaacggcc tgcagggaac
    15961 ttcggtgcgg ccgaagacca caaaacgctc cactaattcg taaccccagc gaagcgccaa
    16021 tttctcatgg gtgatatcgt cgccccattg attcgtttca cgcaggaagc gcttggtctg
    16081 accggtggca cggtccaaca attccggcag cgacttcgtg accaactcgt cgaactcccg
    16141 ttcggtggtc acgacattgt tgagtcgtgc agaaaaaggt tggccgtcgc gcatcgtctt
    16201 tccgtccggc atcttaggag acatagtggc gaattcccca gcaaatgaca attcgacaag
    16261 tccgctccta ggagaccaca tttgtccatg aggggtcaat gggggaggcg ggcgatcccc
    16321 gcattgtatc agggtgaaac aggcttggag gcagatggaa aacggtgcgg ttcctcacgc
    16381 aggggcgggg tggctttcga cgggagaatc cccctacgga cggtcggtgg agagacgctt
    16441 ggccagccgt ctggcgagac gcatcatggc cggggaacgg tcggagggat cgagtaagac
    16501 gttgatgaca tagggctggc tgggatcggc cagtgccttc gccagcgtat cgacgaactc
    16561 accatgagtg gcgacgcgcg agccctgccc ccctccaatg aggtcgcaga tccgttcgta
    16621 tcgccattcg tgaatatcgt taaacggtcc ttccagaatc tcgcgttcgg tggaatagcc
    16681 gtgattattc aggacgatca cgacaggcgc ttgccggtat cggacggcgg tggagagttc
    16741 cgaaccggtc atctgaaacg ccccgtcgcc caccagaacg atagggcgca aggacggatc
    16801 ggcaaacgag gccccgacgg ccgccgggac ggcgaagccc atcgacgtat agtaggccgg
    16861 cgagagaaac tcaaagcgcc ggtggacgtg cagatcgacg gaggcaaaga gcgattcgcc
    16921 gacatcggcg atgaccagtg ttttctcctg cagcaccgta tcgagatggc ggaatacgcc
    16981 gtgcagactg accgaggcgt ctgccggagg cataggttct tccggagcac ggggagcggg
    17041 cagctgtggt ttgggaaagg agggcagcgg ggcattggca agtgctttga cgaaatcctc
    17101 gaagcggatg gaatcgtacc gatgatgttt gatggcaacg cgatccgcgg tggcgtggat
    17161 ggtatggcca tcggaaaaca gggcgctgcg ggcgtcgaga tcctcaacat ctgacaggat
    17221 cgaaccgagg atgagcaggc aatctgtttg gttcacaaat tccttcacct cgtcacgggc
    17281 gaccaagcca ctatagacgc cgacatagag cggatggtct tcgcggatga tggactttcc
    17341 gaggagggtg gaggcgatcg gcacgttcaa ccgttcgacg agtttcgtca gctcgtcgtg
    17401 gagtccaaag cggcccactt cagcgccggc taagatcacc ggacgtttgg ccgactccaa
    17461 catcacgcgc acctcggtca ccgcttcact tagggcggcc ttgtctgttg gttcgtctaa
    17521 gatgctcgtt ttatgagacg tgtacgccag cggcacatgg accatgtcgc gcgggatctc
    17581 gagatagatc ggacgtcgat agcgcagcaa ggcggcaaac gcgcgatcca tttcgcgctc
    17641 cgccgtcagc ggatcgtcca ggctgaccgc cgccaccgtc attttttcaa acacctcacg
    17701 ttgggtcgag aactcccgca ccatatggtg gagataggga ttgcgcgcgc gctccgagag
    17761 tcctggtgat ccggtcagca acacgacagg tgatcgttcc gcataggcgc aggcaatcgc
    17821 attgaccgtg ttgagtcctc cgacacaata ggtcacgcag agggccccga tgccgttgat
    17881 ccgcgcatag gcgtcggcag caaagccggc gcaatcttct cgcgtggtgg ccacatgttg
    17941 aatcggcgag gactccatca atttatagag gctcagcaca tagtcgccgg gaatgccgaa
    18001 catatggcgg acgccgaggc gatgaagccg atctaaaact gccgtgccga tcgtgtgtgt
    18061 cgtcataagg atggacgctc cgttaccagg tggcgaggcg agggatctat tctcgcagca
    18121 aaccataggt gcctgggaag gtcaagcgcg cgaacaatcg tgacgcacgg ttgcttcagg
    18181 gaatgatttc aggcaccctc gtgagccatt tgcaccgcat ggccaacatg ccattgaaca
    18241 cctctaccct ggatacatca ccaccatgac acagactatg accagttcca ccgcaagagt
    18301 ccgcctgacc gccgagcgtg ccgggcctcg ttactacggt catctctggg tcttcgacaa
    18361 caatgtggcc gaggtgctgg gcacgccggc cgcgggggat ttggtcgatg tgtacaccca
    18421 tcagaaacgg tttttcggac gcgggttgtt caacccccac tcaaaaatcc gcatccggct
    18481 tctgaccttt cacgaagaac cgatcgatga ggcgtttttt gccgcgcgac ttcgtgctgc
    18541 tgcggcgctt cggcgtactg tcacccctca cgcgaacgcg tgtcgtcttg tccatggcga
    18601 gagtgacctg ttgccgggcc tggtggtgga ccggtttgcc gatgtcgcgg tgatgcaggc
    18661 cctggggtat ggcatggatc tgcgaaagga cctgttgggt gacctcctgg tgcaagaagc
    18721 gggagtgaag agcgtctatt tgcgcaatga tgcgaaaagc cggacgctcg aagggctgcc
    18781 gttgtcgaaa ggattcctgc gtggcgaggg accgacgacg gtgcccatcc acgaaggcaa
    18841 ggctcagttc acagtcgaca ttgcggaggg gcaaaaaacc ggctggttct gcgatcagcg
    18901 ggagaaccgc ctggcagcag cggcctatgc caaaggaaaa cgcgtgttgg aggccttctg
    18961 tcataccggc gcctttggag tgcaggcggc cttggccggt gcgcaatcgg tcgaaggcct
    19021 ggatgtgagt gcggcagcgg tggcgttagc ccaagcgcat gcggcgcaga atcatgtcgc
    19081 gtccatctgc acctatcggc aggccgatgc cttcgatgaa ttgcgagtgc tggaacgcaa
    19141 tcagcaacgg tatgatctgg tcattctcga tccacctgcc tttgcccgga gcaagaaagc
    19201 cctgcctcat gcgttggccg ggtataaaga cgtcaatctg cgaggcttgc gccttcttca
    19261 gtcggggggc gtcctggtga gttgttcctg ttcgcaaccg gtgagtgatg acgatttctg
    19321 gatgatgctc cagtcggcgg cgcgggatgc caatcgccag atccgtctgc tggaacagcg
    19381 ggggcagggg ccggaccatc cggtgctggc cgggatgccg gagacacggt atctgaaatg
    19441 tttcatcgtg caggtcttct gaggcgatga tgcacgagcc tgaacggctg tcagagcctg
    19501 tcgatgcgcc gcttgtgccc gcctccgtgt cgctgccgga aatcactccc aaagccgtcc
    19561 tgctctcggt tctactggct gccgtcttgg ctggggccaa tgcctacctg ggcctcttcg
    19621 cggggatgac cgtttccgcg tcaatcccag ccgctgtcgt ctcgatggcg gtgctgcgcc
    19681 tgtttcgcca gtccaacatt ctagaaaaca atatcgtgca aaccgccgcc tcttcgggtg
    19741 aggcattagc ggcgggtgtg atctttacta tccctggcct ggtcctgatc ggctattgga
    19801 cgagcttcga ctattggcaa acctttacgg tgtcgttggt cggcggagta ctgggagtct
    19861 tgttcacgat tcccttacgc cgtgccttga tcattcacgc gcggctgcgt ttccctgagg
    19921 gagttgccac ggcggaggta ttgaagatcg gcgccacatc aggcggcaat gccggtcgcc
    19981 gggttcgcct gttgttgagc gcgtcagcct tggggggcgg gttgaagttt gccgagggcg
    20041 gcttaaaact ttggagtgaa tcgttggagg gtgcgcttga gctgggtcgt atgacgttct
    20101 acggaggcct caacctctcg ccggcgctgg tcgcagtggg gtacatcatc gggctcaata
    20161 cggcgctggt ggtttttctc ggcggagcaa tcggctggct ggtgctcctg cccttgtacc
    20221 aagcccttgt ggggacgccg gctgatgtga ccggtgtggc ggcggcgaag gtcgtgtgga
    20281 gcgggcagat tcgctacatc gggatcggcg ccatgctcgt cggcggagtc tggacgctga
    20341 ttcaagttcg agggcccatc ctgcacagtc tccggcagtt gctttcgctc tatgctgctc
    20401 gtcgcgacga tcgtggtgcg tcggcgccac tccgcaccga gcgggatgcg ggcgtggtct
    20461 ggctcatcgg tctgacggtg gcttcgctga tccctatggt attcctgtac cgccacctgc
    20521 tggatcacag cctattcgct ggcgcgggat taaccgtgct gatggtggtg acggcgtttc
    20581 tcttttctgc cgtggccggg tatatggcag gcctggtcgg cagttcgagc aatccggtgt
    20641 cgggtgtcac gatcgccacg atcatgctcg cggcgctgct tctattggcc atcctggggc
    20701 gtgaacatcc ggccggtccg gcggccgcct tgctggtggg ggcggtcgtg tgttgcgccg
    20761 cagccatggg tggcgacaat ctgcaggatc taaaaaccgg acacctggtt ggtgcgacgc
    20821 cgtggaagca acaggtgatg caggtcattg gagtggcgac cggtgcggtg gtgatcgtac
    20881 cggtgctgtc cttgctacag gcgaaatatg gaatcggagt ggcgaccgcc gcgcatcccc
    20941 atcccctgag tgccccgcag gcgactttga tggccaatct tgccaaggga gtgttcggcg
    21001 ggtcattgcc ctggcatttg gtcggcatcg ggatggcgct cggcgtggtg atcatcgcct
    21061 tggatcagcg gcaggcccaa cgtcaggctc agcttcgttt cccggtgttg gctgtcgcgc
    21121 tgggtatgta cctgcctctc aaattgtcgg cggcgatcat gttcggcggg ttgctggccg
    21181 aggctgtgcg aaggggcaga ccggcttccg agactccgac tgacgatcaa gggctcctat
    21241 gtgctgccgg gctcgtcacc ggggaagcga tggttggtat cctgctggca gttcccattg
    21301 cgttgagctc tgtgtggccg tcgttggcag gagatccgtt tcagttgttc gccgatccgc
    21361 cgttgggcgg ctggccgggg cttctcgccc tggcattggt cggcctcttc ttagtgcgag
    21421 ccgcacaagc cgcaggaggt gcaggcaatg ctgacgccac ccctaggggc gtgtgacgtc
    21481 gcgtgaatga ggaggacgga agctagtcgc tgggtggctc aaaatgtccc ggcggccggg
    21541 attgccatgg gacggtggcc tgtttggatt gtttcacgag gctccgcagg ctgacttcgg
    21601 cggcacggag aagtttcggg tcgccgctct gcatcaatgc ggtgagcagc acgaacagcg
    21661 ttcgatcatg cccggctgcc aggagcaacc tgtccagcac ggggtctgcc ccggttagcg
    21721 tggagagcgg agccggttcc tcctcggcgt ctttgcagag gaggtcgaat tccgtcgggt
    21781 gaatgaacag ccaggaaagg ggaatttgca gagctttggc gaaggcttcc agcgttgacg
    21841 cagtgggatc gagctgttca gactccaatg attctaagag attcggggtg attccagctc
    21901 gctgggcaaa ggcctgctcc gaacattttt gagacactcg ccatgcgcga accaaggctc
    21961 cgatgtgtgg catggcgccg atcatactgc atcccttttc ggcactgcaa cgtcgctttt
    22021 tctcatgttg agggatactt gtctgcaaga tcaatacgtt atgatccatt ctcctaggta
    22081 gaacaaaggc atacaaatcg ggtagaatga gccgttctta ttgatatccc cagcgaggag
    22141 gatcagccaa tgttaggaac cgacattcgc ggcattatgg ccgaagagga agaagtccag
    22201 cggcggcagg aagccttgca gtcgttgatg tcgatgcgcg agaggctgct gcgtgaatcc
    22261 ttggaagcgc ggatcaagcg ggcacgtgga acgggagact ggaccaacct gtctcctgct
    22321 gaatgtgcca gtatttacaa agaggaacgc gtgcaccttc gggctcaatt ggaacgattg
    22381 aaggccgagc gggaccgcac acgcggcaag ctgtcggctc tcaagcgggc gaaagtgcgt
    22441 gcgcaacgta tccgtgccgc ggaagccgct tcggggaaga aacgtaaata ggatagatag
    22501 cggggaggtg gtgctattcc gcactcctcc ccgcagtgcc gcagacctcc aggtatctgt
    22561 tgaccttctc atctcgcacc gtctctcgca actttctctc ccatatcagg gatgtcgcta
    22621 agacgaagcg tacgcgcgac cgcgaacgcg tctttgtgct cgaaggcaca aagccgattc
    22681 ttgaattagt gcgatcggcc cctcgccaga tcgtctgtct cgttgtcgct ccgacgtttc
    22741 tcgaacgcca gtcaccgggt gatgtgcagg agattgtccg cagcgggtgc accgtgcaca
    22801 cgtgcccgga acatcagctg gcccagttgt ctgatgtcga aacctcgagc ggtgctctcg
    22861 ccattgtgca tcaaccgacc tgggatcagg ctgccatgct ggcgcagccc agagtgttcg
    22921 gtctctacgg agacatgttg caggatccgg cgaatatcgg aacgattatc cggacagcag
    22981 cgggactcga tgtgagcgcc ttatggatgg caccccattc tgtcgatgtg ttcaatccaa
    23041 aggttgtgcg ggccacggcc ggcacgctgt ttcaactccc gattttctct cataccagct
    23101 ttgagaacct gctgtcttta ggatgtacga ttctggcagc cgatgtcggg gcccattcga
    23161 acagcgtccc gatccggtcg attcagtcca ttcccgctcg caccatcgtg gcgatcggca
    23221 gtgaaagtcg tggcttgtcg gatgccgtcc ttgacgccgc cgcgatgcga tttacgatcc
    23281 cgctcaaacc aggggtcgaa tcactcaatg ccgccacggc ggccgccatc gccctgtttc
    23341 atttgtcggg attaccggta gaatcatagg ccgctcatca ggcgcgcacg gcgttcaaga
    23401 ccgctgcggt ccggtcatcg ccgtcgcgtg ggatgttcgc aaaatctccc cgcatcgctt
    23461 tcagggcata tcgttcctgc tcgatttccg tctgagtccg cattcccaat cgacgaaaga
    23521 tcggaattgg tgggcaccat ccttgaacgg catgttggag taaaaatcct ccgacgacgg
    23581 ccgggaggag aaaccagcgc cggttcacca gacttccgag acagaggccg gtcaaggcga
    23641 tcgtcgccgc gttggcctcc agcagccgtt ccacgtccca ttcgcggtcc agttcgcgta
    23701 ggcgttcact gatggcctgt gctccaccct ttgcgaaata ggcaacattg gcttctgttt
    23761 ggcggcgaat gcgcgcattg atgtccgcat cggtccggtc agccacccgt gacgtcgtcg
    23821 gcggaatcag atcggtcatc gagagcctcc tttgtttctg tgttcggcac gtcatccact
    23881 atgagattca gagggcaacg atgtggacta ggcattcccc gcggaggcct tatatcgtct
    23941 ccagatctcc ttcctttttc tcgtccgttt ctattacgat gccggtacac aggtgctgag
    24001 cctgaggcga acatcaatga aggcgaagac gacatttcat tgtcaggcat gtggccacca
    24061 agccccgcgc tggctcggac gctgccccga ctgcgggggc tggaacacgc tcaaagagga
    24121 gcgcctgcct gccgctccca aaggtcgcca ggccatgccg cttacggcca tggcggttgc
    24181 cacacccatc tctgacatcg aaatcgtcgg cgagccgcgg catagcaccg gaatgggcga
    24241 attcgatcgg gtcctcggcg gcggcgtcgt gcccgggtcc gtgatgttga tcggcggcga
    24301 cccgggtatt ggcaagacga cgttattgct gcaggccttg cccctgctgg cggagacagg
    24361 cgagcaggtc ttatatgtct ccggtgagga gtctccccgg cagatcaaga tgcgagggga
    24421 acgcctcggc atcggcggca agcatctcct cattctcgga gagacatccc tcgaacaaat
    24481 cctcaaagcg atacaagaaa tcaagccggc agcggtcgtc gtggattcga ttcagacagt
    24541 ctacaccgag caattgactt cggcgccggg gagtatcagt caggtgcagg aagttgccgg
    24601 gcagttgatg tggttcgcga agcgcaacaa tgtccccgtg tttatcatcg gacatgtcac
    24661 gaaagaaggc gccattgccg gaccacgctt gctggaacat atcgtcgata cggtgctgta
    24721 cttcgaaggc gacaagagcc acagttttag aattttgcgc gcggtgaaaa atcggttcgg
    24781 gtcgacgaat gaaatcggcg tattcgagat gaaggatggc gggctggagg aagtcagcaa
    24841 cccctcggag ttgtttctcg ccgaacgccc gcaacgcagc accgggtccg tcgtggtgtc
    24901 cagcctcgag gggacacgac caattcttgt ggaacttcag gcgctggtat cgggaacgaa
    24961 ttatccgatg cccaagcgga tggcgaacgg agtggaacca aatcggttgt ccttgctgct
    25021 ggccgtgatg gaaaaacggt tgggcatgca cctctcggga caggatgtgt acgtgaatgt
    25081 agtcggcgga attcatatcg atgagccggc catcgacctg ggtattgtgg ccgccgtgac
    25141 gtcgagtttg cgcgagagcc cgattgattt cacgactctg gtcatgggcg aagtgggctt
    25201 gggcggcgag gtccgggcaa tcagccaggc cgagatgcgg attcgcgagg cggcgaagat
    25261 gggtttcaag cgttgcctgt tgcctgagcg gaacgtggcg aaactcgatc cggtagatgg
    25321 gattgaactg gtcggcatcc gtgaggtcgg agacgcgctg gatgcggtgt tggcatgagg
    25381 accgtggcta cgaaaaccgt acgcgtaaac caagtgcgcc aattactgag tatcctcctg
    25441 ctctgggtct tcacgctccc cggctgcgcg ctctttggtc caaaagacac cactccgctc
    25501 aaagaggcga cggcggagca gttgaccgcg ctcttaaaag agcaggcggg agaagtgcga
    25561 accatcaaag gcctcttcag tgccaagatt accggcggca tcttacccat cggccaacga
    25621 gtccagggca cggtgtttta tcagcggccc aacgcgatca ggcttcgtgg cttctcggcg
    25681 gtgggtagcg aaattttcga gttcgtccaa ctggaagatc aattcaagct gcggctgccg
    25741 acgatgggcc gtgaagtgac cggtcgatct tctgaagccg atcaactggg acagcttacg
    25801 cgtccgtttc agttgagtgt ctgggccatg agtggcgtga cggggacgca agccgtcggc
    25861 ccgcaggagc aggttcggtt gtcggaggac ggctctcgat accgcctgga tgtgttgacg
    25921 gcaccgggac cctctggggc ggctccttac ataagtcgac gaatctggtt tgaccgtcgg
    25981 aatttgctgg tggtgcagga agaacggctg acacccgccg gcgagatcga agcgacgatg
    26041 caactcgatg actatcgggc agtcggcccg ttgtcgccgg ccaccttggc ctccaatgga
    26101 caatcgccag agaccgtcac gcgcatcatg cgtcccttta ccattcgcat gaccgatggg
    26161 cagggatccg gaagtctgca ggtgacattc catgaactgg ttccgaatga gccgattaaa
    26221 ccgggtgagc tgggacgcgt atgaaggtgc aaccggatca ccacctgtta gcaatcgata
    26281 ccgcgacggc ctggcagagc gtggccctgt tgagcggtga gaaggtgctg gccctcgttg
    26341 agcaagatgc cgacggatcg cacgcacggt cgttactggg cgccattgat cgtgtgttgc
    26401 gtgagacgag cattacactg aagcaacttc agagtctggc ggtatccatc ggcccaggtt
    26461 cattcaccgg tttgcgggtt gggctcgcga ccatgttggg gtttcgtgcg gtattgggtc
    26521 ttccgattgc accggtcccc acattggaag ccatggcctg gaacctgcgt gacgcgaaag
    26581 ggctcttggt gccggtcctg aaaagccggc acaacgaagt ctattgggct gcctatgagt
    26641 ggttaccgga atcgggccta cggaccctca tcgccgagca ggttgggccg ccgggttcgg
    26701 tagctcgagc cttacagggg agcaattcct gcacagtgtt cggtgatgga tggcaggcgt
    26761 atgagaacga tatcaggaat gctatcgagg ccgtcggcgg gcaagtgcag gaagtcagcg
    26821 aggaaacaca ccgtccttcg gccgtgagtg tggggttggc gggccaacgc cgtctggacg
    26881 ggggacagat tgcggaacaa gaattggttc cccgctatgt tcaacgcacg gaagcggaag
    26941 tgaaatttga cgaacagcag ggcgtctccg cgcttgagcg gcgacgccag cgagtggcca
    27001 gtaagctgac gcagcgacga gctcgacctg ttccaaaagg cagtgatgtc cgacgcagga
    27061 cgtagtgtgc cacatggagc ctgttctctg agatgacatc gacgtcgatc ttgattgaac
    27121 ctgcgacacc agccgtcctc gatgaggtgc ttgccattga acaggcttgc ttctcagccc
    27181 cctggacgcg caaaatgttg gcagccgaac tctccggcaa ccaatttgcg aactttttga
    27241 tcgcgaagtg ccccgacccc ttgtcgggat cctttgcggt ggctgggtat ttttgttttt
    27301 gggtcgtgtt tgaggaagtg cggctgatga acctggcggt cttggaaccg tttcggcggc
    27361 aaggcgtcgc aacgaagttg gtctgcaccg ccctgcaaac tggagtggaa cgtggtgcct
    27421 ccagggcgat gctggaagtg cgggaatcga atctcgaggc acagacgctt tatcgccggc
    27481 tagggtttcg tcagaccgcc aaacgatcac ggtattacaa tcatcccgag gaagatgcgg
    27541 tgctgatgga aatgacgccg ctgcaggtga gtgaggtgtg tcggcagccc ggagtgtgag
    27601 ctccgggagc cgggtaacgc gatggtcatc cacgaacgta tgtagtcaac caggaggtgc
    27661 gacatgcaga cggagacggc gattactgag cggttacggc gatccaacac agaattccgc
    27721 gcactggaag aatctcacca tcgcctcgat gagaaattag ccgatctaca acggcggcac
    27781 gtgctgacgc cggccgaaga agtgctgaag aaacagctgc agaaagaaaa actggccacg
    27841 aaggataaga ttgccgaact cattcgatcc tcacggtaac gaagatcgat aggagttctg
    27901 cgccgggctc ttctcgcgga cggatggggc agagcggaga gaccgagcgc ggaggcattg
    27961 gttcagaccg gacatgctcg caccactggc cgcccatatt cagtcgctga aaaagcggtt
    28021 gctgatcatc gcggtcacct tgggggtcgc gtttgcgtcg gcgtttgcct attcaacgga
    28081 gatggtcgcg tggctcaacc gtccgttccc caaccagctg gtcttctacg gaccgaccga
    28141 agcgttgttt gcctccatca aagtgtcgtt tctggctggc atcattctca gcctgccgat
    28201 cgtgttttac caattctgga aattcatcga accagcgctg cttccaaagg agcagcgctg
    28261 ggcaattccg attttcctgc tcgcggcgct cctgttcgcg ctcggcctca tcttttgtaa
    28321 tctcgtcatc ctgccgctgg tcatcgactt ttttgtcagc ttcggtatgg atcgcgacat
    28381 cacgcccgcg ctcggtgtcg gcacctatat cgatttcaac gtcaaattcc tcctgatctt
    28441 cggttgtgca tttgaactgc cactggtgct gaccattttg tcccgggtcg gcgtggtctc
    28501 ggcggcggta ttggcccatt accgtaagca tgccatcatg gcggccttga tcatttcggc
    28561 catcgtgacg ccggatgcca ccctgttcac catgttgctg atggcggtcc cgctcatggt
    28621 actctatgag atcgggatca tcggcgcgaa gatcttcggg cggtcgtcag gaccggcgcc
    28681 cgacatgaat ttgcccctcg acccggatat acccatcggt accgccgggc atcgcgtccg
    28741 ataggccggc gttcacaatt tttgaagggt gatctcctat gctgcgtcac atgttggtgt
    28801 tgacggcgtt gacggtcggc ggtttacagg gattagtgca tgccgctccc tcgctaatcg
    28861 ggaatgaggg aggaggcgcg ctgaagttag aacagggaca tcccgggcag gatccttcct
    28921 caccagccga tatcggcaac acgagtattc aagccctcgc gtcaggtgcc ggaggcgtga
    28981 tctacgcagg ctcattcggc atgggcattt tccggagtac cgatcggggc ggcacctgga
    29041 tgtcggccaa tgagggactg accgatccct tcgtgctctg cctcaccacc gccaaagacg
    29101 gcgcgatcta tgcggggaca tttcgtggcg gcgtgttccg ctcccgcgat gccgggaaaa
    29161 cctggcagcc gatcaacaag ggactgaaac ggttggagat caaagtcctg atgatggacg
    29221 ccaagggact gtatgcagga accggcgacg gtgtctacct gttgaatgcg gcgcaggatc
    29281 actggaaagt cgtgaccacc ggcctggatg agattctggt tcatgcgctg gcgaggactg
    29341 atgatggcac gctatatgcc ggaacctcag gcaaaggggt gcatagttat aaagaacgca
    29401 cgccgggatg gacgcgcctg cgacagggcc tcaaagatca cgagggcttg gtagagaatt
    29461 ttatccgcgt gctggccgtc gataaggagc aaggggtgta cgccgggaca ttcgacggtg
    29521 gagtgttccg cagcggcgat ggtggcaaaa cctggttgcc gatcagccgt gccctcccga
    29581 atgactccat ccgcggtttg atcagcaatg agcgcggcgt gtatgttgcc acgggacggg
    29641 ggattttcaa gaccgtcgat aaggggcggc aatggatgcc gttaaataag ggcctcagca
    29701 atctatcggt acaagtgttg atcgagggcg ataagggcgg tttttatgcc gggaccagtt
    29761 ccggcgtgtt tcgcagcgat gacgacggcc tcacctggac ggcagtcagc caagggttag
    29821 aaggcgagag cgtcgcgccc ttcaagttta actgagtagg aaaggacacg agatgacggc
    29881 acaaaccggt tcaccacaag cgaccattac tgtgacatcc aagaacgagc cgtgggggca
    29941 gatcgtgctg cgctttttcc ccgacgtagc gccgaatcat gtgaagaact ttacggacct
    30001 ggcgaagaaa gggttttaca acggcaccac ctttcatcgg gtcattccag gcttcatgat
    30061 tcaaggcggc gatcccaaca gcaagaatcc ggatcgcgcc tcgcacggga tgggtggacc
    30121 cggccacaat gtgaaggccg aattcaacag caagccgcat aagcggggaa cgctgtcgat
    30181 ggcgcgcgcc aatgatccgg acagcgcggg ttcgcagttc ttcatctgcg tgaacgacgc
    30241 gaatttcttg gattggcaat atacggtgtt cggggaagtg cagagcgggc tcgacgtcgt
    30301 cgacaaagtg gtcggagcca agcgtgacgg acgggacaac ccgctggagc gcgtggaaat
    30361 gaccgtgacg attaccgaat aatgcgacgc accgttgaag cgtaaggaga cgactgcgtc
    30421 atgaccccgg tgcttcggtt cctacgcgtc acggttcacc tttcacaggt cgcggtgttg
    30481 gccgcagcgg tgttcaccgc tgcgggctgc gccattcctc aggtcccgtc gcggaccgtc
    30541 tacgaagacc ccgtcaattt cgtccggttg gaattggatg ccaatgtgct gccggagtgg
    30601 ccgcccgggc attttacgca tccggcccgg ttttctcagg agcaggtcag gcgggtgctg
    30661 atggggctca cggttcagga acaccggacg atggtccagc gctggatcgg cgatgactct
    30721 cgacgattgc ccatgttccg cgatgcggag atcatgattc tcgtgcctca actggtcgag
    30781 gccctacggt tagcacgaga aaatgagcga gtgacctact acctcagcca gcctcaaacg
    30841 tcggtgaagc ggacgatcac ctctggaggg atgtatatcc ggggtaccga actgcacttt
    30901 attttgggga attggcagac gctgtatggc attccggctt acgggatgat ttacgatcga
    30961 cggtacccga tgaatcccat catctccaaa ggattcgatc tgtttttcga cctcgaccag
    31021 gcgttagtca ctcaaacgac cagcatctgg gatgggctcc tcgccaatac aaaagacgaa
    31081 ctggtgatcg atctcgcgat tgtctttccc ggtcagaata tctgaaccgc ccgtcgctcc
    31141 tgaaacggtt cctgcagtct gtggaagcct cacgacgccc tagtatgccg ctgcgggtgg
    31201 tccttccgcc tgactccctg catcaccagg gcgggaagcc gtcgatgcgc ggctcatcag
    31261 aagaatccgg ccggtatcgt cgccttggga agtataggcc agcgtaactt ctgcgatctt
    31321 ataatcgtac tgcgtgtccg cgagtcgcgt ttgcgccgct gtgactgcca cttctgattg
    31381 cgtcacttcc acgaccgtgc ccaacccgag tttgtaccgc tgtttggaca actgcaacgc
    31441 ctcttgtgcc gtcttcacct gttcttccgc cagtgtgatc tgttgcgcga aggtgagagt
    31501 gtcgaggtag gcattcgtca cttgctgcgt cagcgcctgc tcgatgttac tggttgcagc
    31561 ggaagcggcc tgccggttgg cgttggcttc cacgacctgg ttttcgatca ggaagccggt
    31621 gaacagcggc atcgagacca tggcgccggc catccaccag ccgccggtct gctggttctg
    31681 gcgcggatcg aatggatcga aggtgccgcc gctggcgatc gccgacacgg tcgggaggta
    31741 ttggcgtttg gtcgcggtga ggcgcgcatc ggcggacgcc gtctgctctt tcgcccgttt
    31801 gacttccgga tgagagaggc tttcgttgat cagggtctcc agcgttttct gcgggcgaac
    31861 ggcaacggaa atatcctcaa ggacatagtc atcggcgccg gcgatgccca tcgtgcggtt
    31921 gaggtcggcg aaactggctt tgaggtcgtt gcggctccgc accagcaggg attgggcatt
    31981 cacgagttcg acgcgggcca ggtcgaagtc caatttggat ttcagttgct ggcgataaag
    32041 cgtttcgatc tggccggcga tgatgccacg ctcgcgaacc gtttcttccg cgatctgcac
    32101 cagacgatgc cgcttcagac tattcaggta cgcgcgctgc acatacagca acaccagcgc
    32161 acgtcttgca ttgacatcct gcccctgcgc gcgttcggcg agtttgttcg actcgatgag
    32221 gttgctggta tagccgaaat cgtagaggcg ttggttggcg atcacgcctc cggtaaaggt
    32281 ggtttggttc tcgcgcaaca atcctcctcc gatcaggaac cgtgggttgc tcacgccggc
    32341 accggcgacg gtgttggcgt tggcgtagac ctggggatag tacagggagc gtgcctgttc
    32401 cgtacgcgcc tccgaagcct tcaagttggc ctggccctcg atcagcatcg gatggttctt
    32461 gacggcaatt tccaccgctt gctgcacgcc gaggaaactg ccgcgtgaca atggcaccgg
    32521 ctgttctgcc tcggcggcat aggtaccgga ggctgatgct gccgccaggg acagggcggc
    32581 cagcatgaga gaggtgctgc gtagcagtaa ataagtcatg ggcgatctcc ctgtgtctgg
    32641 gccgctcggt ttgtaggggg cgcggcggtc ggcggtggag gagtgccgcc tggcgcgcgc
    32701 cgttcaaatt tctgttggga aagtttggcg tccggcagat tgaatggcga ggcgacgacc
    32761 ggcatccctt cgagcagacg acgtttgcca acggccacca catcttcgtc ccctcgcaag
    32821 ccggagctga tctcgatcca ccggccgtcg ctgatgccgg tttgtaccgc caccggtttc
    32881 gccttgccat cttcgacgac gaagacggac ttgcccttcg gcgtgctggt gatagcctgg
    32941 gggggaacca cgagcgcctg cggaatttca cgcagaccga gggtgacttc ggcgaaggtg
    33001 ccgggacgga gtgcgtggtc ctggttaggt aaatcgattt cgaccagcag actacgcgtg
    33061 gccggatcga gcgccatggt ggagcgggtg acgagaccgg tgaacgagcg ggacggcagt
    33121 tcggtcacct tcaccgtggc ctgggtcttt cccggcacga tccaggggct gtcgtcctgg
    33181 ggcacattgg cataaatgcg cacggtgttc agatccatga tcgtaaagag gggaatcgcg
    33241 ctggtggccg aggacgtggc gatttgaatc aaggctccgg ggtccgcgaa ccgggccgtc
    33301 acgatgccgt cgtaaggggc gcggactttg gtgtaatccc gcatgacgac gcgctgttcc
    33361 atcaggtgcc ttgctccctg ataagccgct tcggccacgt ccacgtcctg tttcgcgatg
    33421 acgtccggcg actctttcca gactttcgcc agccgttcgt aggtcagctt cttaattttg
    33481 taatccgaca ccgcctgctg gtactgctct tccacttccg gcgcgtcgat gaccgcgacg
    33541 acatcattcc gcttcacggc atcgcccttg tccgggccaa tccatttgag ataaccggac
    33601 actttggcgt agagcgtggt ttgatagagt ggagacacat tcgcgggcag tttgaccgta
    33661 tagaccaaat cgcgtctggt tggcttggtc acctgcacgt ccacgggagc gctgtccggt
    33721 accgccacgg attcctcggg cggttgtggc ggggtgggca ctgcgggaga cgcaggggga
    33781 accggatggc ccacgtcatg gatctctcgc caatacagaa gtccgccgat gacaagtgtc
    33841 agcacgatgg cgagggcgat ccagcggatt ttccggcgcg tggccctgac ggggcggaga
    33901 gtcgttgacg gttcgtccat taaatgtcct ccgaggtcgc gggagccgtg gcagagagcg
    33961 gcgcgcgttc ccgacgaatc aataccagac tgtgcatcac cggtacgacc agcagcgtca
    34021 tgatcgtact gacagccaac ccgccgacca ccgcgcgggc caacggcacc atggtttcgt
    34081 tgccctcgcc gaacccgagc gccaggggca acagacccag gattgtggcg agcgccgtca
    34141 tgaggatcgg ccggatgcgc cgccgcccgg cttccagtac ggcatgcgca gcggtcgagc
    34201 cgttgcgcac catgcgattg gcgaaatcga cgagcagaat actgttcgac accacgatgc
    34261 ccatcatcat cagcgtgccg atcatggatt ccacgttgac cgacgtgttg gtcacgtgca
    34321 gggttaacac cgtgccgatc cacccaagcg gcacggccac caggatgatc agcggatcga
    34381 taaaggagcg gaacaaggcg accatgacca gataaatcaa caccacggcg agcgggagcg
    34441 ccagggcaaa gttttgaatc gccccgcgca tgttggccac ttcgccccgc agctgcacgg
    34501 tcacgtcctt cggcaactga atgcccgcca acacttgctc gatatccttc gcgacatggc
    34561 cgaggtcgtt gccgacgggg gtgacgagca cattgatcaa ccgcgacaga tcgtagtggt
    34621 cgaccgaatc gggaccggtc ttgaacttca gttgagccac atcgcgaagc atgacgggcg
    34681 gcccgcgtcg gtcgtcgctg gatgcgtagt agccgctcgc gatttccatc tgccttccgg
    34741 caaacggggt attttggagg gcgagcgtgg atccctgaat gccgcctccc gtgagactgg
    34801 aggtagggag gagaggggtg cgcgcgccga tgatcggaat gttgagcaaa tcttcggtcg
    34861 tcgtcagtga ttgctcggga tactgcgcca gcaggaaata cccgttggcg gttttgggat
    34921 cgagccagta gttgggcgaa agggccaggt tcgaactgat gccggtgatg acgtccacga
    34981 cgacgcggtt ctgattgata ccgtaatagg cggccttggt gcgatccaca tcgatatgca
    35041 attccgggta actcttgccc tgcttgattc gcacatcgac ggtattgggc acctgggcga
    35101 tctgctgttg aatccgctcg gccaccggac ggatcacgtc gagactcgga cctttcactt
    35161 gaatgtcgat cggggctttc aatccgaaat tcaacacatc gctgatgatg ccgccggtct
    35221 ggaaagagat ctcgacaccg ggcagcgagg tcttgagcct gctccggagc tgggcaatat
    35281 agtcctcggt gcggccttcg tgtcctgtga tgaggttgac gagcacgaag gcggtatggt
    35341 tgcccgtgtt cggggcgaat cgagcggcat cgccataata gagaccggtg ttggaaatca
    35401 cttcttccag atccgctttg gggatcgtct catgcaccaa ttgttcgacc tgtccgacga
    35461 tggccgtcgt cttttcgatc cgcgaacctt ccggcgcggt gaccagcatc gtgaagttgc
    35521 ctgcgtcgac ttttgggaag aattcggtgt gcaagcgggg aatcaagaag gcgccggtgg
    35581 cgatcaacgc gaccgtcgcc aggccgatca cgaccggctt gaagcgcagg ccgcccttca
    35641 agatcggctc atagatggcg agcacatagc ggaaccatcc ttcatcggcc gaggcctcat
    35701 gttccgtgcc tttgccatgt cctccctggt agagccaggc gagcactacc ggggtgaccg
    35761 acatggacac gacatagtct gccagcatgg caaaggcgac ggtcatcgcc agcggcacga
    35821 agaggtactt gatgatgccg gtaaaaaaca tgatgggcag atacacgatg aggatgcaga
    35881 tcgtggcgac gagaataggc agcgtcagct ccatcgcgct gtcttcggct gccgagcgtc
    35941 cgtccttgcc catttccaag tgtcgatgca ggttttcctg cacgacgatg ttgttgtcga
    36001 gcagggtgcc gatgacgagg gccaatccgc cgagcgtcat gatgttgacg ctttggccgg
    36061 tcagatacag ggcaaccagc gccaccgtca gcgagagggg gatggccaat ccgaccacca
    36121 gcgccgcttt cacgctggcg aggaaaataa agatcatcaa cccggccaga ccagcgccca
    36181 gcaagccttc cttctgaaga ttggcaatcg actgccggat atagagcgat tgatcgtaga
    36241 gaaacttcac agtagtgcct gcgggaattt cggtgagttt ggacagtttg gcgcggatgc
    36301 catcggtgac ttccagcgta tttgcgcctt cctgcctggt gatgggaatg taggtggctt
    36361 cgcggccgtt cacgcgcacg atcgaggtct gtacggcggc gctgtcggcg gccgtgccga
    36421 tatcgcggat cagaaccggg gtgccgttga cgatcttgat cggtaggtcg ttgatcttgt
    36481 ccacgacgtc cacaaggcta ttggaataga cgtaatagtc caggtcgccg attttgatgt
    36541 cgcctgcggg aatgatggcg ctctgctggt tgagcgcgtt tacgacatcg gagggggaga
    36601 taccgcgcgc aagcaaccgc tgttggtcca ggaagacggt aatttgccgg accttgccgc
    36661 ccaagggcgg accgaaggaa atgccgggga tattggcaat ctgctggcgc acggtgaagt
    36721 aggcgagatc gcgaatttct ttcggaccga gcgcatcgct ggaaatagac aggtagccca
    36781 ccggcaaact ggagacaccg aatttataaa cagagggtgg atacacgccg ggtggaagca
    36841 ggcggatgat gctataggcc aggctggtca gttcggattg tgccgcgtcg atgccatagt
    36901 ccggttgaaa aaagactttg atgtagctca tccccgcgag cgattgggat tcgatatgtt
    36961 cgacgtagct cgcttcgacg aagcgttgct ccatcttcag cgtgatcgcg ccttccattt
    37021 cgctgggact caagccgcga tagaacgtgg tgacaaggat ggagggcagc ttgatttcgg
    37081 ggaagatgtc cacgcgcatc ttctggtacg acacgccgcc gagaatcagc gcgatcatgc
    37141 acaaggcgaa gacggcatac ggatttttca gcgcggcacg ggtcagcatg gggcagccat
    37201 ccgttgggtg cagttatgtt ccagccaaaa tttccagaga tgcagggaaa gggtcacgag
    37261 gtcatcgaat tgtcccggct tgacgacgta cccattggcg cccccgctgt agcaggcccg
    37321 aacatccgcc gtgtcgtctg agctagtcag gatgacgaca ggaatgtgtg cgacgcgcgc
    37381 ctcctgcttg atgcgtttca acacatccac gcctcgttct cctctgagct tgaggtcgag
    37441 cagaatcaag gccggctcct cgtgctgcac atgttcatgc aggtaggcca tggccgcctg
    37501 gcccccttcc acaatatcca gccgcccctt gtagccggtt tgcgtaaggg cctggcgaaa
    37561 caattcgcat tcgccggggc tgtcgtcgat aaggaggatg gagcatgagc taggcatggc
    37621 agatcagtaa cgcaggaatt gtgccgggat catcgagtgg tgtggtgtcg ccataagcct
    37681 acgaaagcgc aagggtctgc gggcgcacat gagaggaggt tgcttcagcg acggggacga
    37741 cgccgcgaca ggtaggaaga aattccagag gggtagggca atattcccgt gtgcgttctg
    37801 aagccagttt tgacaaatgt ggaggggctg cccgggattt gtcgatctgc ctccagggcc
    37861 tttcctaggc cggttgtctg gttgaaatgg ctagcatagc tccagacgtt gcgagagggc
    37921 accgaacatt tccactcccg ccttcgattg ctccaggagg attcgtcgtc atgtcagatg
    37981 atcattcgac tccggactcg agtcgcgggt ggcgtcttat ctgcaccagg gattttgggt
    38041 tgctgtggtg gggacaaacg acgtctcaga tcggtgaggg gctcaacaag gttgcgctgt
    38101 tgtggttcgt gtatgagctg accggatcgg ccatgaagat gaccatggtc ggtctgttgc
    38161 agacgattcc tccgctcgtg ctgggtccgc tagtcggcgt ctatctggat cgcatgccca
    38221 aaaagcctgt catgatctgg gtcgatattc ttcgcgcgct gctcacactg ctcattccga
    38281 cgctctatgc gctggacatg ctgtcgatta caggactgta cggcattatt tttctcacgt
    38341 cggttgtgtc caccatattc ggtcccgctc tcgtgtcggc ggttccgtta ttggttcggc
    38401 cttctgaact catgtcggcc aatgctctta ttcagggcac caataatatc gggatgctgc
    38461 tcggcccggc gatcagcggc attatgatcg ccctcatcag ggcagagaac gtgctgttcg
    38521 tgaattccgc cacattcctg atatcggccc tgtgcctcat gccgatccgt ttctctcctt
    38581 cgcatgccgt gtccagcgag caggctacgt ccgtctggca ggaactccag gtcggatttc
    38641 gattcatctt cggccagcag tcgatggtcc tcacgctagt gattatttca tcgctctaca
    38701 atctcggcgt gagcgccttt gtgtttattt tgccggttta cgccaaggag tttcttcagg
    38761 tcggcccggt acagttgggt tggttgtggt ccgccctggg tgtcggcatg ctggcggcct
    38821 cggcctggct ggcgttgaag caagagagtg atatccaggg gcgcttgcgc atcgtcgtga
    38881 gcgggatgac gatcggcggc ctggcggtat gcagtttgag tctgctggaa acgccgctga
    38941 ttgcggccgg aatcgtgatc atcgtgggag gcagcacggc ggtgctgaat ccgatcatct
    39001 gggcactctt gcaggagtta acgccggaac atctgatcgg tcgcgtcgtg accaccttca
    39061 gcgtcggctc catggcgtcg gcgatggcgg ggatgacggg cttcgggtgg gtggccgatg
    39121 ccgtaggccc cgccgcgagc ctggtggcac tcggcctggt gttgctgctc acggcagcgg
    39181 tggctgtcgc atgcgtgcgt agaacatgcg cgttgccggt ggcgcatgcg tgagcatgtg
    39241 tgacgttcag tatcccccgt cgttcccttc taggacatgc aatgaaccaa ggcgatcacc
    39301 ccgtcgccag cgaaaggatc agaatgcgtg ggacacctct cgcctttcag ccttgctgat
    39361 tcccctcctg ccgcaaacgt ttatactgct aatatgtccg atacccatcg gtggctgctg
    39421 acccgtgact tcggcttcat gtggtggagc caggtgctgt ctcaagtggc tgaaggcgtc
    39481 agcaagctgg cgctgttgtg gttcgtctat gcggtgacgg ggtcgcccct caaaacgacg
    39541 gtcattgggc tcctccagac actgccgccg atactcttcg ggccgttcat cggcgtcctc
    39601 gtcgatcggt ttcccaagaa agcgattttg atcacgagcg atgtcgcaag aggtctgttg
    39661 atcggcctga ttccctgtct ggtgccgatc gaacatttca cggtcgaatc cctctacgtc
    39721 ctgacattcc tgttcggcat ggctacggcc gtatttgtgc cgacgctgtc atccgccgtt
    39781 cccttcatgg tggctcgccc gcagttcacg gcagccaatg cgctgctgca aagcacgacc
    39841 agtctgggta tcatcatcgg gcctgctgtc agcggactcg gtattgcgtt ctcgggatcg
    39901 caggatgtgc tgtgtgtgaa tgcgctcacc tatttcgcat ccgcagcctg cttgttgccg
    39961 atccggttgc gagcgacgga gcaggcacca gactccagtg cgggctggag accgttcatt
    40021 cggcatctcc tcgaaggcct gcggtatgcc tttctgactc atcgcacgct gctgatcctg
    40081 atcgtcctcg cctccatcta cacgttcggc agtggcgcat tcacgacact gtttcccgta
    40141 tttggacgcc aactgctcgg ccttggcccg gtcgaggtgg gatatctctg gtcttggctc
    40201 ggagtggggc tgctcctctc atccataggc ctgatctggt tgagcgcctg ggatcttcac
    40261 aaacggctgt tggcaattgc ggtgtcctgt gcactggcag gtctggcggt agtggggctg
    40321 acatggaccg atagtgtggg cgtcgcgtcg gcttatgtag tctgtattgg aatcggcctg
    40381 ggcacctgga ccccgatcgc ctggggcatc attcaagaag tggctccgcc cggcatggtc
    40441 ggccgcgtga tggccgtgta cacagccatg gccaccgcga cctccatgct ggggatgagc
    40501 gccttcggct gggtagcgga gtcgtttggc tcgattacca gcgtcctcgg aatcggcgga
    40561 gtcatgggtg tgttggcctg gggcagcgcc tggtttggag gaaggattcg aaccgtggga
    40621 gtgacagagg gagggaaccg cagttagcgc aagttgccgc gatcaggaga cgcctaaccg
    40681 cccgcacatc gcccatcctg tacgctcgcc atttccgcct gtcacaaagt tgaaccacac
    40741 ggcttgccac gtacggaaaa aatagggaga atgcgccggc cagtcggcac gacatggcct
    40801 gttcgaacaa tctcactcag tacaaaaaac aacggtatgt gtagttatga atgagaacag
    40861 tgcagagtcg tcgcgttaca cgcgtgcatc cggtcctcgc tgcttaccag tcgtctctca
    40921 ccggtgatat cactgttcca tagagacagg gcgaggtctc aaagcttcgg ttggcttcct
    40981 ccgtggtctg ccgcgttgct cgtcatgctg ttctgcgcat catcgagttg ggcagagatg
    41041 ggagctactg aggaactcgc gaaaaagttc cagacgcctc tgacggatgt cgtctcagta
    41101 ccgtttcagt acaacacctt cttcggtgtc gggccgggca acgccacatc gcacctgttg
    41161 aacatctctc ccgttgtgcc ggttcgcttg ggtgattggc atgtcgtcac gcgcacggtc
    41221 atacccgtga tttcagtgtc acggttcact ccgggtttgg aagatgaaat cccgggcacg
    41281 ggcggtggca cggcgaccgg attgggtgac atcaatttca ccccgtttct cacgcccggt
    41341 cgcaccgggg ccgtatcctg gggcctgggg ccatccatca cgctgccgac ctcgacgatg
    41401 gaagaactcg gcagtaagaa gtggagtgcc gggccatcgg ccgtggtgat gtttcgattc
    41461 agtccggtgg tgggcggtgt cctgcttcgt cagcaatggt cttttgccgg aggccgtcat
    41521 cacccgggcg tcagccagtt tctcatgcag ccgtttgcca gctacaactt gagcggtggc
    41581 tggtttctca cctcggctcc catcatgacg gcgaactggg aagcgcagcc gggcaataag
    41641 tggctggtcc cggttggcgg cggagtgggg cgggcgttta tcctggacca ccagcccatg
    41701 agcctcacgg cgcaagccta ttatcatgtc atcaggccgg atctgggagc ggagtggcaa
    41761 accaggctga cgatgcagtt tctcttttag cctgttgttc agtcgcgcgg acgaacataa
    41821 gactcgggcc gagtgatgca tgctctcgct ctgtaagcct gtaggaaatc ttgtttgtct
    41881 gccagggaac tcaagggctt ctcctagtcc attcgtctca ccggcatcga tattcttttc
    41941 tgtaatgggc ttttcacggg ggcagcgcag aaccgctgaa gtggtccatc aacaggaggg
    42001 tcgaatatgt ccaaatttct catccaggct atcgtcgtgc tggctcttgt cggaccgggt
    42061 ggtcagtttg ttcgggccga tgagggctcc agcaaaagcc accatcagca tctacagggg
    42121 gtcgtgatcg aaaaaggggg agcacttgca gtgaaagttc ccaatggcag cacctatcag
    42181 ctcaatgaaa accgctccga gcgtcatggg catgcccttc ccaaggcagg agacgaagtc
    42241 accgtggtca tcgacgagaa caataacgtg ctcgaagtgc acccgaaagg aactgaagga
    42301 aaacatcggt ttatcacggg cgaggtggta tcgattggcg tcatgcagcg cgagatcacg
    42361 ttgaagacct cgaagggcga gcaaaagttc gcgatggaaa agcaggaact ctcttcttcc
    42421 atcaaggatg gcgcgcgcgt ccgggctgag ttgaatgaag ccggcagcat tattgacgtg
    42481 catccggaaa aatccggcgg cggtcactga cctggctcag taggcgggag accttcacca
    42541 tccctctgtc cggtggatga tcgggcagag ggatgggccg ggacttcacg gagttccgtt
    42601 tactacctgg gcgtccgatc cctgtttctc ttcaaacgtg ccagttccac accctaatcc
    42661 accgtacacc atcccgaaga atccgcaata ggccccagcc ttgaaggccc aatctctgcg
    42721 ggtggcttgt tcgatgcggc catcgtgaat gacaagagag acgtattgac tgccgacagg
    42781 gatcatggca ggcaggggga tgacaacaag atacagcacc ataccggacc atcgtaagcc
    42841 gccggtctta tagatccact cttcccgtcc atccttgcgt aattcgatat tgtcaggctc
    42901 accccattgc gttcgcagtt cagcgaccgt cttgaactca gagggcgtgc ctgccttgcg
    42961 cagatcgatg gcacctctgg tctgatcgat cttcgggtgg tcgctggatt cgctgcgcgt
    43021 gccgagggtc caggcgccca gtccgacgca gcctgggagc atggcgatcg cgatgatcca
    43081 ggctgcatgg cgtaacgact tgtgcatagt gtcctttctc tggcgtgatg gggcgaaccc
    43141 tactcaggtc cctctcgaaa tacaagcagg gcagacgaga cggagactgc cgataccgaa
    43201 ggaagaccag tcgccaaccc ccctcccaag gtaggatacc gcctgaccgg cgagcctcgg
    43261 taggatcccg ccacagggag gttgtgatgg cacctcgtcg gtatgctcga acctattacc
    43321 ggtttccgct caactatcca gtcatttttg gcggagcgcc ctttgtcggt gaaggcgtcc
    43381 tgaccaatct ctcattaaaa ggctgctcgg tgacctgcga tcgcgaagtg ctctgcggga
    43441 gccaggtgcg ggtgagtatg cttcttcatc atcagccgcc cgcgttgccg gttgaactcg
    43501 ggacgatcaa atgggtgcgg gggaatcaat tcggcgtgga gttcgtgcgc gtgcctcttg
    43561 aagctcagca acggctcaac cggacattac gaatggaatt gatcgaatgg ctggagaacc
    43621 gtcaccggaa tagtgcctcg cctgcatcgc cacgtcacga caactagcat acctgcttct
    43681 tcagcgtccg ccccgctagc cccatctcgc ttccccgaat gtccaggatc aggtgtggtg
    43741 tctcctgagg cattcaggta cactacgcct cttagccgaa catcctgcgc atgctgcgca
    43801 cgatcattct gatcgccacc tagaccaaga gccgattcat cgctcgccga tggagcccat
    43861 ggcttctgac ccgcctcctt cagcttcttc atctcaggac gggatccagc agggtggtca
    43921 ctcctggtgg gcgcgtctgg ccgagtggaa tccttcactg ctcacgacgg tcacgctcgc
    43981 cgtggcgacc ggtcttcgta tggcgctgac tccgctgtgg ggatcaggct ataccttcat
    44041 cacgtactat cccgccatca tgttcatcgc cgtggccaat ggctggcgac atggtgttgc
    44101 cgccaccctg gtctcctcag tcctgactat cgtcctgttt tttgatatgc aggcttcgcc
    44161 gggtgagcag cagacggcgc tggcgttgtt tatcaccgcc aatgtcatca tcgtgtcgct
    44221 ctccgaagcg gtcacgcgtg ctcgtcttcg ggcgcaggcg gagacatccc tggtgagggc
    44281 ccaggaacag cgattgcgtc tggagatcga cgcgcgcgcc aaggccgagg agacagtccg
    44341 cgccagtgag cgtcaaatgc agttcgtcac ggatcatgct ccggttctca tcgcacaatg
    44401 cggaacggat ggacggtatc ggttcgtgaa tcagcgatat gccgacctcg tgcgacggac
    44461 gcccgaagat ctcatcggcc tgcatccgcg tgaggtgttg ggcgcagagg cgtaccagca
    44521 ggccgaaccc tatatgcgag aggcgctggc tggacggcag gtcaagtttg atcagcaatt
    44581 tcttggtgct gcgtccatag gccgccttct gcaagtgacc tacgcaccgg agtgggacga
    44641 acgcgggatc gtgacgggat tcattgccgc catcgtcgat atcaccgaac ggaaacaggc
    44701 cgagcaggca cgggccacgc ttgccgccat tgtcgaatcg tcagaggacg cgatcgtcag
    44761 caaagatctc aacggcctca tcaccagttg gaatcgaggt gccgagcggt tgtacgggta
    44821 tacccggcag gaggccgtgg ggcaatccgt gctgctggtc atcccggacg aacagatcga
    44881 ggaggaaacc ccgattcttg cgaagatcgt gcgaggcgag acggttcagc aatatgaaac
    44941 gatccggcgg cggaaagacg ggacgttgat cgatattgcc ctgaccgtat cggcgatccg
    45001 caatgatgag ggacggatcg tcggcgtctc caaggtcgcc cacgatatca ccgaacgcaa
    45061 gcgagccgag gcggcgttgc gggaaagtga ggaacggctg cggctcttca tcgaacatgc
    45121 gcccgccgca atcgccatgt tcgatcggca gatgcggtat gtcgcggtga gccgccgctg
    45181 gctggcggac tacggacttg aaggcgaggt gttgggccgc agtcactacg agatttttcc
    45241 cgacattccg gagcggtggc gaagggcgca tcaggagggc ttggccggcg tcgtgatgcg
    45301 tattgaagaa gaccggttcg aacgttccga cgggaccgtc tattggctgc gatgggaagt
    45361 ccggccctgg cgggacaagg ccggcggtat cggcgggatc attatcttcg ccgaagatat
    45421 cacggacagc aaaaaggccg aggatgcctt acgggaaagc gaggcccaac atcgcgccac
    45481 cttcgataac gcggcggtgg ggattgccca tgtggggctc gatggacgct ggctccgctg
    45541 caatgatgcc ctgtgcgccc tcacggggta ctctcgggaa gagttgctcg ccaggacatt
    45601 taccgaaatt acccatccgg atgacatcga aggggattgg gcttccgtcc gcaggctgct
    45661 ggccggtgag atcgaaacct tctccatgga aaaacggtac atccggaagg atggctcgct
    45721 catctggggg catctgaccg tctcgctgtt gcgggatgag cagggctccg cgcaccactt
    45781 catttccatc attcaggaca ttcagatccg gaaagaagca caagcgcaat tgcgccaact
    45841 ggcggacgat ttggagcagc gtgtcgaggt gcggacgaga gaattggcgg atacgcagga
    45901 caagctgcgc gcgctgacga cagaactgaa tctgactgag catcgtatcc gaaaacaact
    45961 cgcgaccgac ttgcacgact atctggcgca actcctggtg ttgagtcgga ttaaactcgg
    46021 gcaggccaaa ttggaagagg tgacgccggc ggcgatggag gccatgacgg aggtccagga
    46081 agtgatggat cgggccctgg cctataccag gacgttggtg gcacagctca gcccgccgat
    46141 cttaaacgag ttcggactcc tgatggcgct gagatggctg gcggaccaga tgcagcggga
    46201 gctcaccgtg aagctcgatc tggagagtga cgtcctctcc ctttccgagg agcagtccgt
    46261 cctgttgttt caatcggtcc gcgaactcct gatgaatatc gtgaaacatg cggggacgac
    46321 tgaggcgaag atttccgtca cacaggccga cggagtattg cgcatttgcg tgtcggatcg
    46381 cggtgtgggt tgtgacgtcg gtccggggga ggccaagctg gaaccaggct ttggtctgtt
    46441 cagtattcgc gagcgcatga aggctcttgg aggggagttc gacatgcaat cagtccccgg
    46501 cgagggcacg acggccattc tccagctgcc ggttgttcag ccaggcccca cggctgatga
    46561 ggcggtggct gaaacgggtg tcgctgcggt gagtcacgcc gtggtgtccg agccggccgc
    46621 accgggggtg ccgaaactcc ccacaactgc ctcgctcctc gccactccca agatccgggt
    46681 cttgttggta gacgaccatc gaatgttgcg ccaggggctg cggaccatcg tgaacggaca
    46741 tcccggcctc gaggtcgtcg gtgaagcccg cgatggcctg gaagccatcg aattgacccg
    46801 taccctcagc cccgctgtcg tggtgatgga cgtcaacatg ccccgatgtg acggcgtggt
    46861 ggcgaccaaa cggatcaagg aagaataccc cgaaataaaa atcgtggcac tctccatgca
    46921 caactcgccc gatatcgtgg cacgcatgaa gcaagcggga gcgtatgggt atctcaccaa
    46981 agaaagcgct ggtgtccagc tgtgccgagc gattgtcgag gcggccctta gccggccgtc
    47041 aggggcgagc ggagaaggta gagatgtgag ttgtggcccc tcatgagaag aagctgtagg
    47101 gctgcttctt ccaccgcatc attgcaccgt ctgatcctgc ggcagttgct gggagatgac
    47161 gtcaaagatt tgttcgggta ccagctcttt gggaatgaac gcgttcgcgc cgacggcgcg
    47221 taaggcgacc tcgacttccc ggctgttatg gcaagacatt ccaatcacga ccgtgttcgg
    47281 caggagcgcg cgtatccggc gcgtcgcctc aaccccatcc atgcgtgcca tgcctacgtc
    47341 catgaggacc actgtcgggc ggagcgtctg ggccaattgc gaggcggcga tgccgtcggc
    47401 tgcttccccg gtcacacgaa agccgggccg cttgttcagg atctttcgta aggtgtctct
    47461 cagttgcaga ttgtcgtcga cgacgagtat ctcgaccatg aagtacctcc ttcgagtgaa
    47521 gcagaaggct gtcggtctta ggctagcaca ggttcgataa ttcgcgagtg atattgaaga
    47581 acccacctgg tcgtccttga cgcactttct gagtgcgtgt agggtcgcag gcatgaacgg
    47641 cctgcgggat agccggaaac agcctagcat ggtgcgctga cggcgcaggg agcgggtcga
    47701 atcatttcag accgatagga gcaggaacat ggcgatacgt gaacagcgac cggtcgtggg
    47761 cattcttgtc ggtggggggc cggcaccggg catcaacagt gtgatcgggg cggcgacgat
    47821 acgaagcatt ctcggcggct ccgacgtcat tggcattcag gacggtttca aatggatcat
    47881 ggacgggaac accagcaagg tcagacgtct gtcgatcgaa gacatcagtc gcattcactt
    47941 cagcggaggt tcctgtctcg ggacggcgcg tgccaatcct acgcagaaaa ccgagcacct
    48001 cgatgcctgc ctggcaagtc tgcatacgct gggcgtgacc agactgatta cgatcggcgg
    48061 agatgatacg gcattctccg ccttgaagtt ggagcagagg gccggcggcc gccttcaggt
    48121 ggtgcacgtg cccaagacca tcgacaacga tctcgatctg ccgcatggca ttccgacctt
    48181 cggattccag acggctcgcc atatcggggt cgaactggtc aagagtctga tggtcgatgc
    48241 ggagaccacc tcccgctggt atttcgttgt caccatgggc cgcaaggccg ggcacctggc
    48301 gctggggatc ggcaaggctg ccggagccac cctgaccatc attccggaag aattccgcca
    48361 caaacccatt cgtctccaga cgctggtcga tattctggtg gccgcgttta tcaagcggct
    48421 cagtgccggc aggtcggacg gggtggcggt tctcgccgaa ggcctggtcg aaattctcga
    48481 ccaacaggat ttgaacggac tcgaagatgt ggaacgcgac cagcacggac atgtgcggct
    48541 ggcggagatt aatttcggct tcgtgctcaa gcgggcggtg gagaaggaac tgcgtacatt
    48601 cgggatcaag actaccatcg tggataaaaa tatcgggtat gaactgcgct gcgcggatcc
    48661 tatttcattc gatatggaat atacgcggga cctgggctac tgcgccgcgc aatttctgtt
    48721 ggaaggcggc aatgcggcca tggtgtcgat tcaaaacggg cggtttattc ctattccgtt
    48781 tggcgacatt ctcgacccgg ccaccggccg tacgcgcgtg cgtatggtgg acgtcgagtc
    48841 ggagtcttac gtcatcgcac gtcggtacat gatccgcctt tcgtccgacg atctgcacca
    48901 accggatgac ctggttcgat tggcgaccac cgccggactc gcctcggatg attttcgtaa
    48961 acggttcgag tacttgatcg gtaaggatgt gtaaggagtg ttgcagaaca tgatgtctgc
    49021 ccccacgccc gacacggaaa cgacgatcgc ctttgagaac cagcgtgcgg tgctgtcacc
    49081 gtggggcgcc tccttgcggc ggtactttat cgtcggcagt tctggaagcg aaacggacat
    49141 cgtatggggc tattcaggcg gcgggcagaa gaagggcggg cagggcgatg tgctgattcc
    49201 atttccaggt cgcgtggcgg gcggacgata ctcgtttgac ggtcaactac ttcaacttga
    49261 acggaatgat aaggaaggcc cgaatgccat tcacggattt gtgcgaagcc tcccatggac
    49321 gacgcatcaa gccgtcgctc acgccgtgac ctatgaagta agtgtggatg ccgccgacta
    49381 cacctcgcga gggtacccgt tttcgctcgt cgtgcgtctc acctacagtc tgggcattca
    49441 gggattgtcc tgcacatttt ctgtacggaa tgtgggaggt gcggcagctc ccgtcggagt
    49501 aggattccat ccctacttca cggtcggcac cgggctgatc gatgaggctg aggccaaaat
    49561 tcctgccgca ggctttctcg aattcaacga gcagctcgcg cccaccggca aggtgatcgc
    49621 cgcaacagga actgaatggg actaccgcac gtttcagcgc attggtccgc gccgcttcaa
    49681 ccattgttat cttgaattag agcgcgatgc ggcggggatg gccacggcat cactgcgcaa
    49741 tcacaaaagt ggacgcacga ttgatgtggt gatggatcgt gctttctcgg cggtcgtggt
    49801 ctacacgggg gatgccatcg ctgatgcgcc tcgccgcgcc ctggccatcg aaccgatgac
    49861 ttgcgcgacc gacgccttta atcaccccga ctggggactc aagcgactgc ttcccggtga
    49921 ggtcttcacc ggttcctact ccgtcagggc acgcagccgt tgatctgttc cagccggtga
    49981 tgacggtgcg gctttctggt gcagcgcacc agttccaata tcacggctgt ctgttacgaa
    50041 ggccgcgtgg gttcgatgat gcggaaccgc acctcatcaa cctgggtata ggccgacgtt
    50101 tcttcgcctg caaacaggcc gcaccggtag aggccggctg tccagcctgt ggccggacga
    50161 ggcagcacaa aataaccgga ttgatcgttc gtggacatga tgagccggtc ttgcgcgacg
    50221 gctgtgtgtg cgccggccag ttcggcggtc tctttgaagc agcgtgcggc caggggcacc
    50281 tcatcatatg aggcggtgac caggctgaag accagataga tatcctgctg actgcccggg
    50341 aagctgatac ccgggtccaa cggaatgaag tcatgcgcgc cggtcggtga atcatcgcgc
    50401 attacttttt ttgctggaat gacgaaacga aaccaggcga agtcggcgtc ccggccgacg
    50461 agggacgccg caggatccag cgtgttttgc ggcttcaaag cttcgatggc cttcgcggcg
    50521 agttccgcct ccggaggaat cgtcggagcc gccgccttgg cttgagccgc cgtggctgca
    50581 gcgtcttcgt cgacctgctg ggcaaactcc ggcacgtgca ggcggacctt ctccaaccac
    50641 tgtacgaggt tggccttatt caagacacgg gttccggagg ggagctgcac gtccttcgtg
    50701 gatttttcaa actccacggt cgcatcgtac agcgtcttga actgcatgta ggcgtcttcc
    50761 cagcgtccca gctccaccat gcattggccc atacgaaacg ccgtggtcgt atgttcttca
    50821 tcagtcggat cgaattcaga cccagcttgt gacactgcga gcgcgtcctt gcaacggccc
    50881 aaccccatga ggatgagact gagatgccgc ccggccagcg gatccatcgg gttgaggcga
    50941 agaagttctc gatagaccgg ctccgcttca cgaaaccgtc ccgcctcaaa gagccggtac
    51001 ccctccgcgc ggatcatcga ccagtcgcgt aattgtttcg ggctgacatc cggcgtcatg
    51061 accggtgcaa atcggcgccc ccgctccgtc gagccgaaga agacggtgag gagatttctg
    51121 gcagagaggt gaagcggcga gccgggcggg actcgatcca ggacgaactg cacgtcacgt
    51181 tcggcgcctt cgtaatcgag aacatcaaac cgggcccgcg ccagcgccaa ccgccagttg
    51241 agcatgtccg gcccgagttc cacggctttc tggtaggcct cgaaggattc ttccagccgg
    51301 tccagtttcc ggagttcgcg agccaggcgc agatggagca gggggttgtg cggatcgatt
    51361 acggcgatgc gttgaagctc ggcgaccgct tcctcgacct gtcctgatct caccagcaca
    51421 ctccacttgg cccaccggac gtcgagggcg gcagggatgc ttgccaggac agtctcgtac
    51481 gattcaagcg cggcttcggt ttgccgtgag gtggccagca tgtctccgcg aagttgatgc
    51541 agcgcgagcg ctcgcggatg gtcttgaatg ccctgctcga cgatgccgag cgcaagattg
    51601 agcgtcccct gttcccaggc ggccttggca tgttgtgcga tctggccttc cgagcgaagc
    51661 gggaggtcat tggcgaacgc gcccgaaccg gttcccgcaa tgggcgtgag aagcaacatg
    51721 accgataggc tgagcagccg cccatggtgg cgaacctgcc ggtctttggg aacagccata
    51781 cgaaatctat gtgtgatcat ggtggatgtc tctagtgtta cggacgagcc gtctcctgtc
    51841 tttcgatcat tagaggcaga acgagtctga aggattcgcc ttcgcctgat ggatcgagac
    51901 ataagactct atcttactgt atgaacgtct agccctgcga gcgcaccggg ggaccacgcc
    51961 attatgtgaa agtgatgccg tgtgggcgcc gagagaaagt ggcccgatca gaacgacgaa
    52021 gagcggaacc cgctcatcga acgttgacga agcggccttg cgcggtggct cgcagctgat
    52081 tgatctcctc actccgcgtc accgaaagcg gcacggtatg ggagagttcc tggatgagaa
    52141 gatcggtcgt caacggctgt ttgtgataca gcgcacgata taggccagcg accacggcct
    52201 gttcgatttc cgatccgctg aatcctttgc tggcgtccac gagcttcggg agatcgaatt
    52261 gtgcgcggtc ttgtttgcga aggttcagat ggatcgacca gatggcggta cgttcgtcct
    52321 tgtctggaag atccacaaag aatatctcgt caaagcggcc tttgcgcagc aactcgggag
    52381 gcagagccga gagattattg gctgtcgcca cgacaaagac gtcctgtttc ttttcctgca
    52441 gccatgtgag aaaggcgccg aacagccggc ggctcaggcc cccatccgca tctccgctgc
    52501 cgcctcccgc cgacatcgcc ttttcgattt catcgatcca gagcacgatc ggagacaggg
    52561 attcagccat ctcgatcgct ttgcgaaagt tcttttccga ttcgccgacg aatttgtcga
    52621 ataaccggcc tgcatccaat ttgagcagcg gcaagtgcca ttcgcgcgca atggctttgg
    52681 ccgcgagcga tttgccgcat cccggcacac cgaccagcat gatgccgcgt ggcggggtca
    52741 ggttgagcgc cttggcttcg gccgtgaagc ccatcttcgc ccgctccagc caggacttca
    52801 gtttcacaaa gccgcccagt tcgaaccggt tgtcttccaa cggataatat tccagcaggc
    52861 cgccgtctct tatggcttgg actttgcgcg tgagaatcgt ctgcacatcg tcggcggaca
    52921 gcactccatc ttcgatcacg cattgggtga tgacctgccg tgcctgatgc aaggtcaggc
    52981 cttgtaaggc gcgaaggatg gcctcgcagt cctggtccga tgggccggcc atcgtgggct
    53041 tgggggtggc catggagttg agcagactct gcacgacggt ggtcgaggtt ggtcgacggg
    53101 gtgacgttcg cgtcctcaac gattggagga cgctctgaag catcgcgtgt aactcatctc
    53161 gatccgggag ctgcagatcg aaccgcaccg caatctgatc gaggtcgagc ggcagggtga
    53221 tgggatgtcc cgtcatgacg caggttgccc gtgaacggct gaggtgatga ctcacctctc
    53281 gcagttggcg cgcgacagcg gcatcctgca agtgcggggc aagatccttc aaccagaaaa
    53341 tgccttcgac ggtcaatcca ttgagatgtt gaagcgccgc cagtggggtg gcggtcagct
    53401 tgctgaggct cggcccttcc tcgggcctgg tgaggcctct cgtaatcgac cattcgaaca
    53461 ggggcatgcg ttcctgggcg gcgacggatt gcagcaacgt catcacccgg tcttcttcca
    53521 cggtctcgat cacaatgagt ggatgagagg agcgaatcag ggtgcggaga tcgtgcacgg
    53581 tggttgagag cggcatagga atgaaatgct atcacgggcc ccacgcctca ccaagaaaag
    53641 gggcgattgt ggtgggagtg ggaaacgata gcagggatag aaatggatgg tacgtagcgg
    53701 ggaagtccca gtgatcgtgc attcatgttg tgcggatcaa attgacaggt gattccagtg
    53761 agtcaacaat caccaggtaa agtaaaactc tggaagagaa ttcatatgac acctgacttg
    53821 gaaaattcct gcaaagacga agaagcgcgg gcaactccgg tcgcaacatt ctggcgacgt
    53881 accggagccg ctgtggcgga cgtgttactc cttggagcta tcggggcttg tcttggtttc
    53941 ctgtggttcg atcaattagc cgcgcttgga cgaacgggtc gattcattgg tgctgcaatt
    54001 gcgttggtgt atttcgccac attgaatagt caaattggcc aggggcagac tcttggtaaa
    54061 cgcctcgcga aaatccgggt aacagatgcg aagggcgcac tgattagcct gccccggtcg
    54121 gctttccgtg caacaatctt tttcgcacca ttggcactta atggaacagc cactcctcca
    54181 ggaccatatg aacagcttgt gggcattgtc ctcagtattc tgatctttgg tgtaggtgtg
    54241 gcacaggcat atctctactg ttgcaatcga cggacaggtc aagcccttca cgatatcgtg
    54301 gttggaacat ttgtgaggga ggcggagagc gcttcagaga ttcaacagaa gatgtggaag
    54361 cctcatctcg cgattgccgg tggactcagc actctagtgc tcggggtctt gctgctgcct
    54421 tacacctctg atccgcctga ttttgtatcg cagctggcag aggcgcgacg cctggctcaa
    54481 tcggtggtac cggatgcgca tgtgtcgatc agtcggcaga cttccatgat gacgactcct
    54541 gggagcgggc agacccccgc ttcccgggtg cagcttagtg tggaggtgcg tgtaaaaccg
    54601 gaaaatttcg aaagtgttgc agacaacatc gctatggcga tgtttcggtc ttcgtccgga
    54661 gttggtgatg ttgggcaagt ggtgatagtg atttcgtatg gctacgacat catcatctcg
    54721 catgcacgaa caacaaaggt gttcgcgcat actcctcaag aatggcttaa gcgtctcaag
    54781 ctggatgagt tacataatgt cgtgccgcct gcataaccat caatggctgg aagtgataac
    54841 aacgagtagg attgttaggt cggctacagg tacgttctct aaatcacccg cacagtgact
    54901 cgcccctttt ttcagactta ggcgtcgttc tccgtgaggc agcgaccgag accctgttgt
    54961 tcggcaaggt aataggcgta gtggatggct gccaaattcg cgactctctc ctcggcctcg
    55021 tcgcgactgt ctgcataaat gatctgcagg ccgaatcgtg cggtaatgga atcgagaaag
    55081 tcgatcaagc cattgcgatg atactgttcg agccggcccc caccgcgatg agaatgcagg
    55141 gcgccttcga tgacgagaaa acgatggggg atcgcgagca gtggctcgag ttcgcggagg
    55201 aaacgcgggc gattatcgga cggatttgag acaatcgtat taaactcctc cgcacgtcgg
    55261 cgttcgacac aaaagatgcc gggcgcttcg gcgatggcgt aatctccagc cggcagggcc
    55321 tgcgtgcgcg ttcccgcgat ccgaatgagc cctttgaatg cgtagggttg ggtttcgtgc
    55381 acgtcgacca gaagatgaat ggcagggacc atgattttgg gatgactgaa ccgggtgacg
    55441 ttcagcatcg tttgcggtcc gcgtagctcc tgtcgcgggc gtgtcaccgg ttggggacgt
    55501 gggggcgaag aaggtcgcgg gggaggcggc ggtgctgagg gctgttgcct tccgctatcg
    55561 tagcgggcgc gcgctgtggg atcgctgagt gtttgatagg cctgattgat caactgcgtg
    55621 cgagcttcgg ccttcttgtg cagggtggat gaatgtagga agcggtcggg atgccagatc
    55681 tgcatctgtt catgccaggc gcgtttaata tcagcctccg tcgcgtcagc agacaattcc
    55741 aggatggcgt aatagttggt gttgtgttgg tgctgcatgg gtatccctgc gtgttcgaag
    55801 tgtaacggag tgcgacagga aacggctaga ttgaaataag gaaggccatg tgattccggc
    55861 cgtgccattg tgcgagcctt cgaggcggtg tatcgtaggc cggtagaggc gggtgttctc
    55921 atctcatccc agcggaggcg atgcgcatga tcttggtgac ggggggcgcc gggtatatcg
    55981 gttcacatac ctgtgtggaa ctgctcaatg ccggctcggc agtgaccgtg ttcgacaact
    56041 tttccaatag ccatcctgaa gccctggcgc gtgtgcaacg catcacggga aaatctcttc
    56101 gtctgatacg gggcgacatt cgggatcggg cggctctcgt tgcggcgctt cgggagagcg
    56161 gcgccacctc ggtcatccac tttgccgggt tgaaagcggt gggtgaatcg gtcgaaaagc
    56221 cgctgtccta ttacgacaac aacgtggtgg gatcgttgcg tcttctcgag gcgatggggg
    56281 agtgcggcgt cacgacactc gtcttcagtt cgtcggccac cgtctatgga gacccgcaac
    56341 gcttgccgtt gaccgaagat catccgctgt ccgcgaccaa tccctatggc cgtacgaaat
    56401 tgatggtgga agagatcctg cgcgatctgc agcgtagcca tcactcctgg cggatcggca
    56461 tcctgcggta tttcaacccg gtcggggcgc atgccagcgg cctgattgga gaggatccgc
    56521 aaggcatgcc gaataacctt ctcccgtttg tggcgcaggt ggcggtcggc cggcgcgacc
    56581 atctgaatgt gtggggcaac gattattcga ccccggacgg aacgggcgtg cgcgattaca
    56641 tccatgtggt ggatttggcg ctcgggcatc tcaaagcgct gaaggcgctg gatggatggg
    56701 accgcccgaa ggaatgtctg acggtcaatc tcggcacggg gaacgggtac agcgtgctgg
    56761 agattgtccg ggcgtttgag aaagccagcg ggaaggcggt tccctacaag attgcgcagc
    56821 gccgtcccgg cgatgtcgcc tcctgttacg ccgatccagg gtatgccctc aaagcgttag
    56881 ggtggcaggc cgcccgtgga ctggatgata tgtgtaccga tgcctggtgc tggcaataca
    56941 acaatccgaa cggatacaca ggttgagctg attgcggatg atgaaccggc tcacaagaga
    57001 tcgcgcgcaa acagatctgc tcacccaccg tcatcgatct gtggtctggg ttcttggcgc
    57061 cggtgcgctc ctgagcgcgt tcctgtttgt accggccgcg caggcgaatc accgcgatca
    57121 tcaaccccat gcagacgcgg aagtgcccgg tgtcctcggc cagggtcgag aaatcccggg
    57181 tgcacctttt aaagtctttc tgagcacagg tgcagtagcc gatgtcagcg gactggatga
    57241 tgccgatctc gatgcggctg tccagacagt aatcgacacc ttcatcatta tgctgcagca
    57301 tcgtgccgac tatccgcgtt ttgaggagag cctcaagaaa caggcgctca agcaggtcgt
    57361 aatcgaaccg gtcgtggtca atgacgaggg gaaagccttt ccgtttttgg tcgcccgcac
    57421 gaaagaaccg ggccgtgtca cactgctgat cagcgccacc tccctgaagg acagagggta
    57481 tctcaatcat ccggattccc tgctgcctgt gctgtccaga gagtttcagt gggtggtgag
    57541 caaggccgat accgcaccaa aggcgaaggc ggtggccgtg gaacgaaacc tggagaaggc
    57601 ccccatcctc acggacgaag agattgcggg tctctctgcc gaagaacggg ttcggttgct
    57661 ccaacaactc ttcgacacct atctgcgaac ggtagacgat cagaggagcc tcgacggaca
    57721 accctggtac gaagtcggcc attccgcgcc gctaccgccg actcatgcgg attcaaccac
    57781 gaagttgtat gacatccgca ttcgtgaagc gctgcagaag atcgtgcgtg acccgttttt
    57841 tctggagcga accccgaagg cggtccgcaa tcttctcaat ggcaaagtct ggaatgtcgc
    57901 ctatgtgaaa atcgatcaac gcgactggtc gacccgcacg agggtgttgt ccgaggaaaa
    57961 gtctgtggtg gtgggaaaac gggagcggcg catacaaccg gcggcgattc tggtcaatgt
    58021 ccaccgcctc gctgctgcag atgacccctt ttatcgggag acgcaggggc tgccgatggg
    58081 agccctgtca gcggatcaac tggcgcatgt cattgctctg gagatccatc acaacattca
    58141 ggaaaaatcc ctgagcggtc acacggctca ggatgccctc acggcgcccc ggtaagcggc
    58201 gtctcactta cggcgcaatg gttctcgcct cgttcttctg ctcgtatcgc acggtgtcca
    58261 cggaaaacag cggcgcggcg ctgttcgatt ggtgagccgt catccgtggc gatgggccgg
    58321 attgcaagcg cagggtggtc agcagctgcc gaaagcggga ggcgtcggca tcggtatacc
    58381 ggacctttga gacatggatg ttggcataga cgttcccttc ggccatgcag gcgtacaaac
    58441 tcttttgatc gagacgaaca ccctgaaagc gggggagcgt gtattcgagc gtcggcatct
    58501 cgtgtgcagt cgaaagagtg acgtcttttc ctcggctcac cgctgatcct ttctgcacgt
    58561 gttgcaaatg ctcgatgcat ccggcggtcg aagcctttcc ggccacctgc tccaacgcga
    58621 tggcgacctt gatgcctgtg cctggatggg aggccatgag gtagcggcgc ccgttgggtt
    58681 tgagttgatc gcgttcaatg gtgaagccgg cgagatcgat ggagagtccc acatgactgt
    58741 tcgattggga gacgattgta cgagcactgc tttccagtgc tgccgccggt agcgctccgg
    58801 tcaacagcga caccagggtc agacccacac acgcaaaaga catcgatcgg acggtgccgg
    58861 cttgtgatct atccataggt gctcctctcc tcaagcctgt ctgtgcatgc cgtcagtgta
    58921 tggtgaaccg gaacggatcc caagcgattt gctcattccg gcgagcgtac atcaggatga
    58981 caggtaggga atcctcttca cttttcctcg ccggtgtaga gcggtgcaca gtaccgttcc
    59041 actcgtgttg ctctcgcctg tgctgccaac gcgatctccg atagcggccg gtccccatac
    59101 cctgaggcgg tcaaatcggc cattcctgta gttggattcc attgcgttgt cctacgttga
    59161 tctacatcgc ggagaaaatc tctgtgccga cggcttttct ctgtcctgaa ttcttgacgt
    59221 gatgcatggc tcggtgtatt ttgcccgcct gattttttgt ctacgtattc ctgcgttgct
    59281 gtgatgagcg agaacgactg ccttcgaagg cgaggaaagg gcgccggtcc aaggccggcc
    59341 gtcctggaaa gcaactgacc gaaccattgt gatggagaga cgcacatggg ccgttccggg
    59401 atgttgttgt gtgcgatggt cgtgatgtgg gccggtttat gggaagtcgg tgcggcggca
    59461 gagccgtcgt cggttcctgc ggcagaagcc ctgcgaatca tgcagttcgt cctgacaggg
    59521 actgtgtcga cggaacgcgc gcgcggattt gtgaatgaag cccaggctgc agggtttacc
    59581 gcggtgcagg tgctgctgac cgacggtgtg cagttcgacc atgccccctg gatacccgtg
    59641 aaaaccgcct ggacgaaagc ggagttcctg tcctgggccg attatgcccg tgcccatggc
    59701 ttggaagtca ttccagaggt caagctgctc acgcaccagg agcaattctt tcagcgccaa
    59761 tatccgggct tgatgttcaa taccgtgtcc tacgatccgc ggaaagatgc gacgtatgcg
    59821 gtggtatttc cgtttctcga cgaactgatc gaggcggtgc atccgcgggc gatccatatc
    59881 ggccacgacg aagctttcgg atggaccgtc ggtcaggtgt cgaaatggtt gaagctgggt
    59941 gaagtgatga tcccggcgga tctctttctg cgggatgtgg tgcgggtgca tgattatctc
    60001 ggcaagaagg gggtagaaac ctggatgtgg gcggacatgg tgttgagccc ggcggaattt
    60061 cccggcgcgc agaccaggca tctccatggc atcgcggcgg gatacggcaa agcgctacgc
    60121 cagcagcttc cacgggatat tgtgatgtgt gattggcact atggcgatga acagggaagt
    60181 tttccgtcga ttgacatcat gcaaggggaa gggtttcgag tcattggtgc gacctggaaa
    60241 caggagtcgg cgacgcgcaa gttcagccgc tatgccttat cccggcacgc ctatggcctg
    60301 atggccacaa ccgggtttca tattcagcag aacgatacca aaatgatcca ctggatcatc
    60361 caggcgtccg gggctttgtt tcgcaatccc gaggcagtgg tgccgcctat gcccgcgtcg
    60421 gctggttcat cggaaggaag gggataatcc gccgactgca caatcggcaa gttgactcca
    60481 tctatcccgg gcatgggcca tatggttcat gcccgggatc tgtgctccat tcatcggccg
    60541 tccgtcagct gcctccaagg tcttctccgt atccctctat tgatcattga gaatgtgaac
    60601 gtgcagttga ggctcgtcca tttctgcccc gagtgcaggg gagtggaccg caccagcctt
    60661 gaacacgtag aatgcgcctc ttcggttgac gctgcccctt cagcagtaga gatatgggaa
    60721 cggcgggccg aatcaacagg gccatgacca ggaagggatc gtcatgagtg tgaaatgtgg
    60781 aatcgtggga ctgccgaatg tgggcaagtc caccctcttt aatgcgctga ccaaatcggg
    60841 gatcgccgcg gagaattatc cgttctgcac gatcgagccg aatatcggga tcgttgaggt
    60901 gccggatgcg cggatgcagg cgctggccga tatcgtcaag ccgcagcgga tgcagtacgc
    60961 cacgaccgag ttcgtggata tcgcgggatt ggtggcaggg gcttccaagg gcgaagggtt
    61021 gggaaaccag ttcctcgcca atattcgtga gaccgacggg attgtgaacg tcgtgcgctg
    61081 ctttgaggac gataacgtgg tccatgtggc gggaaaagtc gatccgattt ctgacatcgc
    61141 caccatcgtc accgagctcg cgctggccga cctcacaacc gtggaaaagg cgcaagagcg
    61201 gaatgtgaaa ctcattcgct cgggagacaa agacgccgcc aagttgggcg acctgcttgt
    61261 gcaggtcgcg gcttgtctga acgagggcaa accggcgcgg acaatgaagt tggatccggc
    61321 gcaacgggca ctgctgaaac cgctgtgcct gctgacgatg aaaccggtga tgtatgtggc
    61381 caacgtgtcg gaaaaagggt ttgccaacaa tccgctcctg acgcgtgtgg aagactacgc
    61441 ggcccaggaa ggcgcgccgg tggttgccat ttgcgcagcc ctggagtcgg aaatcgccgt
    61501 actctccgac gaggaaaaac aggaattcct ggccgatatc gggatgaagg agccgggact
    61561 gaatcgcctt attcgcgcgg cctatcagct cctcggcctg caaacgtact ttacggccgg
    61621 ggtgaaagaa gtgcgcgcct ggacgattca tatcggcgac accgcgccgc aggccgcagg
    61681 cgtcattcac ggtgacttcg aaaagggatt catccgggcc gaagtcatcg gctacgatga
    61741 ttacattgcg tgcaaggggg aggcgggcgc gaaggaaaag ggcaagatgc ggctggaagg
    61801 gaaggaatac gtcgtgcgcg acggcgacgt gatgcatttc cgtttcaacg tctaggttag
    61861 tgccatgacc atgttatgag gcagtgaatt cctgcctgat tggagatcga tgatgaacga
    61921 acaggatacg cagcgcgcgg tagcgattct caaccggatc atggagctgg aactggcggg
    61981 tgtcgtgcgg tacacgcact atgcgctcat gatctacggg tacaatcgta ttccgatcgt
    62041 gtcgtggttg aagggcaacg cggatgagag cttggcccat gctcacaagg ccggcgaact
    62101 ggtgaccctg ctgggtggcc atccgtcgct gaagatcggg accttgctcg aaaccgaaaa
    62161 acacgatatc ggcgatattc tgcgggagag cctggagcat gagaaggccg ccgtcgcgtc
    62221 ttattacgaa ctactgaagc tggcggaggg taaatccgtc ttgttggagg agtttgcccg
    62281 ggaaatgatc gtgggcgaag agctccatct cgacgaagtg aataagatgc tgcgcaaatc
    62341 gggtgatgta caggcctttc gttcctgatc attaattggc tggaggggta agttgtccgg
    62401 gcaaccggct ggctctcccc tcggctcata gccgtcgatc tccgccgatc catctccctg
    62461 tcatcatgtt tgatgtcatt ctgtatcagc cggaaattcc tccgaacacc ggcaacatca
    62521 tccggctgtg cgccaatacc ggtgcccggc tgcatttggt gaaaccgttg ggattcacgc
    62581 tggaggacaa gcaactcctc cgggcagggc tcgactacca cgaattcgcc acgctcgccg
    62641 tccatgagac ctgggaaacg tgtctccagc gtttcacagg gcaaagactg ttcgccgttt
    62701 cgactaaagg aaggcagcgg tacgatctgg ttcaatacgc agagggcgat gcgttcgtgt
    62761 tcgggccgga aagccgcggt ctgcccgcgg agattcttgc aagcgtctcc gatcagcaac
    62821 gcattcgtgt gccgatggtg cctggaagcc gcagcctcaa cctgtccaat tcggtggcgg
    62881 tggtgctcta cgaagcctgg cggcaggcgg agttcggaca gtgcctgtga tggtctcgaa
    62941 tctgctcctt gccgtccgtt aggcagatag atcgtttcag gacaacgctt accgggagtc
    63001 aaatctccag taccaatccg atctcgacca cctgctccga cggcagatgg aagtaagaac
    63061 tggcgcgctg ggtattgcgc gacagcacca caaacagttt ttcccgccag atggccatcc
    63121 ccggcttggg ggttgctaaa aaggtaatcc tgctcaggaa gaaggtcgtg ttctgtagcg
    63181 gcaacacatg accattcgca gcaagctgcg tgagcacgcg cggaatatcc ggcgtctcca
    63241 tgaagccgca acgggcgatg acttgaaaaa gaccctcgta cacgggggtg atctccaatg
    63301 gcgctcctgc cggaacaaac ggcacatgtt ccgtccgaac ggtgagcaaa tacacatgct
    63361 cgtgcaaggt tttgttatgc cgcacatttt gcagcagtgc cggcggggtg atgtcgggat
    63421 gttgtgaaag gaacacggct tgtccggcgg ttcgatactc taccttcgac aagacgtctc
    63481 cgacgaattg atgcaagggc gggaactgaa cacggagatg ctcggcaacg atcgcacgac
    63541 ccctcgccca ggtgctcatc acggtaaaaa tcgccgcgcc gaggagcagt ggaaaccatc
    63601 caccatgagg aatcttctgc gcgttcgcga gaaaaaaagc gagatcgata catagaaatg
    63661 tccctacggc catgagtgct ggcagtgcgc tccatcccaa atgactgcga gtgacacggt
    63721 acatcagtag cgtggtgatg atcatggatc cggatacggc gatgccgtaa gccgcggcca
    63781 ggttggtcga cgatccgaat gagagaatca gcccgacggt gccgatgaac atcagccaat
    63841 tcaggagggc gaaatagatt tggccatgct gctccgcgga ggtgtgcgta atccggagcg
    63901 gcggaaggta gccgagttgc accgcctgca atgtcagtga aaaagccccg gacagcatgg
    63961 cctgcgaggc gatgatcgtc gctaccgtcg ccagcgcaat cagcggatag agcatccagt
    64021 ccggagccag gtgataaaag ggattggcga gcgccgccgg attccgcatc aagagcgcac
    64081 cctggccgaa atactgcaac agcagcgccg gcaacgcgac cgcaaaccag ccgagttgta
    64141 tcggccgacg tccgaaatgc cccatgtctg cgtacagggc ctcagctccc gtgagaacca
    64201 gaaagacact acccaacacg agaaagccga tgccggcatg gcggagaaga aacgtggcgg
    64261 cataaagcgg attggccgca agcagcaccg ccggcgtttg aatcaaactg tgcagcccga
    64321 gcaaggccaa ggcggcgaac cacacgagca tgatgggacc gaacacgctt cccagcgctc
    64381 cggagccgcg gcgctggatg gtgaagagca gggcgaccag gccgacggta atcggaagca
    64441 catagggagt gaacaaatcg gtggccagcg tcagcccctc caccgcgctg aggacggaaa
    64501 tggccggcgt gatgatgcca tcactgtaca gaaaggcgac gcctaccaac cccagtgaga
    64561 cgacgaggct taggcccttg cgcagattga ctggatggga gcgttgactg agtgccatga
    64621 gcgccagcat gcccccttcg ccgtcgttat cggccttcat gacgaacagc agatacttga
    64681 ccgtgaccac gagcacgagc gaccacacga tcaacgagag gatgcccagc acgttctccg
    64741 gcgtgaccgc cagtccatgc gattcatgaa agcattcacg cagggcatac agggggctgg
    64801 tgccgatgtc tccatagacc acgcccatgg cggcaacggt gagggatgcg gatgcggatg
    64861 aagtctgcag gtgtttctgc atatgcggga catcgggtgc cgaaggcccg tcatggaggc
    64921 ggcttccggt ggcgaacgcg actataccat gtccgacaca tgaatgccgg tgcgtcagca
    64981 cgtagctggc atcgttccgg cctggaagtt cctcgaatct tctgctaaat tccgaccggt
    65041 catcgcaagg gcatcgccag cgcgccgccc aactcgtcca cttcatctga caagaaagct
    65101 gcagacaccg gtcagagcaa tccggccgcg cctcgctttc ggaaagcctg ttagacgcct
    65161 atgactgcct ccacgacgcc gactatttcc gccgaagccc agcagcgtat tgtcgatctg
    65221 ctcgccaaag aactcggcgt cgcctcaccg caggtgtcag ctgccgtgac cctgctggac
    65281 gggggcgcaa cggtgccctt catcgcgcgg tatcgcaaag aggccacgaa taatctggat
    65341 gacacgcatc tccggacatt ggaagaacgg ctgctgtatc tgcgtgaatt ggaagagcgg
    65401 cgacagacga tcctggcgtc gatcgaagag cagggcaaac tgactgatga actgcggcgc
    65461 gccatcgaac aggccgcgac caaacaggcg gtcgaagaca tctatctccc gttcaagccc
    65521 aaacgtcgaa ccaaggcgca gattgcacgc gaggcggggc tggagccgct ggcagacgcg
    65581 ctgctggctg atccgaccct cgatccagaa caggaagccg tcaagtatgt gaaggtggtg
    65641 gccgcagccg aaggtgtcga ggcgatcaac gtgcctgatg cgaaggcggc attggaaggg
    65701 gctcgcgata tcctcgtcga acgattcgcc gaaaccgccg atctcctcgc cctcctgcgt
    65761 acgaaattgt ggaatgaagg cattgtgacc tcgacggtgc tgccgggcaa agagacggcc
    65821 gaagaggaaa agttccgcga ttactatgcc tattctgaaa ccattcgcac gattccttcg
    65881 catcgggcct tggccatgtt ccgcggccgg acgcttggtg tgctgaaact ggaccttggc
    65941 ctgggtgaga cgctggatgc tcaggtgccg catccctgcg ccgcgctcat tgcagcccac
    66001 ttcggcattg agaacaaggg ccgacgcgct gataaatggc tcagcgatgt ctgttactgg
    66061 gcatggcggg tgaaagtgca tctgcatctc agcaccgagt tgctgctcca ggtgcgggag
    66121 gcggcggaag cagaggcgat caagatcttc ggccgcaatc tccacgagct cctgcttgcc
    66181 gcgccggccg gtccgaaagc ggtgctcggg ctcgaccccg gtattcgtac cgggtgcaaa
    66241 gtggccgtgg tggatgccac gggtaaactc ctggacacca ccacgatcta tccgcatcaa
    66301 ccgcgcaatg actggcaggg ggcgctggcc accctcgtag acttggtgat ccggcatgga
    66361 gtggaattga tttcgatcgg caatggcacg gccagtcgtg agacggacaa gctggctatt
    66421 gaagtgatca aggtcgtaac ggagcgaaag ccggaacaga aggtggccaa aatcgtggtg
    66481 agtgaggcgg gagcgtccgt ctattcggcc tcggccttcg cggccgcgga atttcccacg
    66541 ctcgatgtca gtttacgtgg cgccgtgtcc atcgccagac ggctgcagga tccgctggcc
    66601 gagttggtga agatcgatcc caaatccatc ggggtggggc agtatcaaca tgacgtcaat
    66661 cagcgggcgc tcgcgcggtc gcttgatgcg acggtcgaag actgcgtcaa cgcggtcgga
    66721 gtggatgtga acacggcttc ggctccactc ctggcgagag tatccggctt gaatcgggtc
    66781 ctggcgcaga acatcgtcga gtatcgagat acgcacggtc cgttccccaa tcgcacgatg
    66841 attcgcaagg ttccgcgctt gggcgagaag accttcgagc aggcggcagg atttttgcgg
    66901 atcaataacg gcgacaatcc cttggatcgt tccgccgtcc atccggaggc ctatccggtc
    66961 gtcgagcgca tgctggcgcg tttgaacaaa ggaatcgcgg aggtcatggg gaagcccacc
    67021 gtgttgaaag atctctcgcc ggcagatttc accaacgaga cattcggctt acccacggtc
    67081 cgggacattc tgacggaatt ggaaaagccc ggccgcgacc cgcgtcctga attcaagacg
    67141 gcgacgtttc gcgatggcgt ggagtcactc gctgatttgc agcccgggat ggtgctcgaa
    67201 ggcgtggtga ccaatgtcgc ggcgttcggc gccttcgtcg atatcggcgt gcaccaggac
    67261 ggtctcgtgc atgtgtccgc cctggcgaac aagtttgtga aggatccaca cgaggtcgtg
    67321 aagccgggcc agattgtgaa agtgaaggtg ttatccgtcg atgtggctcg tcagcgcatt
    67381 tcgttgacca tgcgtatgga tgatgccgcg acggctgccg gacaaccgga tcttcgcgca
    67441 ggggcggtac gcgaggggag ggatcggcgc caggatgcgc cgcggcctgc ttcccagcct
    67501 caaccgacca gcgcttttgc tctggccatg gcgcgcgccc agcagaaaaa atgagtgtgt
    67561 gtgttcgacg cagctatctg tgaccgggag tagacctagg gcgtgatctt gaagaagttg
    67621 ccgcctttga gccgttcgtc gtccgtgccc cagacgatct gtttttcgcg tcttgcgaga
    67681 agcgggacat gtttggagca gtggatgtac gcttcttcca cgccgacaac aatccaggcc
    67741 ttgggctgac ggcccccctt gctgtgagcc gcttctctca tgccggaagt gatattgggt
    67801 aacgtcgcga tctcctgtgc atccatgacg cgcgctgttc cattcacgtg tagcccgata
    67861 gtcgtctgat agtaatccag aaagatcagg ccgatgtgag gattctcgag gatgttcccc
    67921 acgctggaca gcaccccatt ccctctgtat tccggatagg ccagcgtctt gtcatccagc
    67981 acttgcacaa aacccggtgt gccggcgcgg aaggaacagt cgcatttccc tcccgcgtct
    68041 gcggtcgcga tatgcatcat ctccatgcgg gcgatgaatt cccgcatcgg ttgattgaga
    68101 gacgccagga cttgatgttc atagaatgcc gcggcgcgat cggatgtgcc gaatcgtgcc
    68161 tgtgcctgct gttcgcccga tgatccaggc cctctcatac ttgctgctcc tttgcctcct
    68221 gtttcgaacg aatcaaggca ccgatatcgt caggcagtcc gtccttgcag tcgatgccag
    68281 gactcacgcc agactgccta cgctagtggc cggcctcgta tttcttcagc ttggccaaca
    68341 gggtcttgta gtcgatctga agcgtatggg cggttttggt cttgttcccg ccgcaggcct
    68401 gcaggacgcg ttcaatgtgc cgccgttcga tttcctcgag aggaagctgc gactgttctt
    68461 ccgagacact ggtcgtggat gatcgaggaa ggacctgcag gacttcttcg ccggtgatgg
    68521 gaccggtctg cgggctcatg aggaccaggc gctcgatgac attgcgtagt tcgcgcacat
    68581 taccgggcca acgatacgag gccaaatgcg ccagcccttc gggagtcggt gttctggcgg
    68641 tcgttcccgg aaggcgaaga ttgtgcagaa tatgctcgac caggccgggg atgtcttcgg
    68701 ggcgttcccg tagcggcggc acgcgcaggg tcacggtatt gatgcgatag agcaggtcat
    68761 cgcgaaaccg tccctgaaag acgagttcct gaagatcccg attggtggcg cagatgatgc
    68821 ggacatcagc ccggagtgtt cgcgtactgc cgacaggacg atattcgttc cggtcgagaa
    68881 agcgcagcag gctcacctgc atagggcccg gcatttctcc cacttcatcc agaaacaacg
    68941 agccgccttc ggctgcggcg atgaggccag gtttggccgt ggtggcgccg gtgaacgcgc
    69001 ctttttcgta gccgaacaat tcactttcca gcaactcgcg gctcacagcc ccgcaattga
    69061 cggcaatgca cgggccttgg gcccggtggc tctgcgcgtg aaggaggcgc gccaccactt
    69121 ctttcccgga acccgtttcg ccctggatga ggacgggggc ttgcgagggg gccacctgcg
    69181 caatctgggt ctccaacgtc tgccaggcgt tgctgatccc tttgaccagg gcttcttggc
    69241 gatagccgcc atgccgcgct gccagattct cgcggcggag ttcccgcacg gttcgcagtt
    69301 tggccagggc ggcctttacg gccgtgccat cgaatggcgt gtctttgatc aggaaatccc
    69361 aggccccatc cttgatggct gccacggcgt ctttgacgtc accatgaccg gtcaggacga
    69421 tcacgtccac atccggttga tggtctttca cccagcgcag cacggcgcgc ccgtcgacgc
    69481 cgggcattcg caaatcggtg atgacacaat cgaagtcgcc ggtgcgaagc gcatcgagcc
    69541 cttcctgccc gccacgtgcg atccgcgtgt cgcatccttc ctcacggagc gcctgctcaa
    69601 cgaccaggcg gacaaattct tcgtcatcga taatcagggt gcggatgcgt tcgctgctca
    69661 tga
//
LOCUS       DAOQPD010000010        67738 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_139_length_67738_cov_20.512463, whole genome shotgun sequence.
ACCESSION   DAOQPD010000010 DAOQPD010000000
VERSION     DAOQPD010000010.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 67738)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 67738)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67738
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_139_length_67738_cov_20.512463"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            131..1237
                     /locus_tag="PK063_04060"
     CDS             131..1237
                     /locus_tag="PK063_04060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HMZ96248.1"
                     /translation="MYIWELPDWPRFRWQADKLLNPLGDAHLKQGRLLGKMMQLGFEV
                     RLEAELLAVTDEAVKSAEIEGEHLDPSSVRSSVARRLGVRGAALGQEDRRIEGMVAMM
                     LDATGQLDTPLTRERLYGWQASLFPTGYSGLRKVKTGGWRDDADGPMQVLSGPVGREK
                     VHFQAPPAERVDAEMDALLSWLNAPLTIDGILHATIAHLWFATIHPFADGNGRIARAL
                     AERSLARSEQSPQRFYSLAGQIHRERPEYYASLEVTQKGDLDITQRMLWFIECVSHAI
                     DAAEAGCADVLRKAAFWQRHTGLALNARQRKVLNRLLDGFEGKLTARKWAALTKCSLP
                     TAQRDIKELMDQGVLIRNEGGSKNTSYSLTGPPE"
     gene            2184..2396
                     /locus_tag="PK063_04065"
     CDS             2184..2396
                     /locus_tag="PK063_04065"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96249.1"
                     /translation="MNNFETFNSVNTLVDRAVRYVVKRYDAADGRIDKDGFPLDVAQR
                     IGSSTNVRPKPRRRSAIAPLERAASV"
     gene            2881..3189
                     /locus_tag="PK063_04070"
     CDS             2881..3189
                     /locus_tag="PK063_04070"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96250.1"
                     /translation="MRTLPRLAAGLSALLLTGCVDLSFRITPENLSVKPMAEGKTCIY
                     TLFNFGYGTNTVEQAMANATPPIQNIRSISVTMFHFLVFESHCLKVVGESAPAGEGAR
                     "
     gene            3226..3528
                     /locus_tag="PK063_04075"
     CDS             3226..3528
                     /locus_tag="PK063_04075"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96251.1"
                     /translation="MRTFCTLTVCLAVLLLTGCVSITNRVTPEDLSVKPMAEGKTCMY
                     TLFELGYGTNTVEQAMANATPPIQKIRSVSTSLFFLLFVNKSCLIVVGEGAPASAP"
     gene            3587..3889
                     /locus_tag="PK063_04080"
     CDS             3587..3889
                     /locus_tag="PK063_04080"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96252.1"
                     /translation="MHRLICCTCWLTALLLSGCINLSIRLTPEDLSVKPMAEGKDCAY
                     AVFGFGYGTTTVEQAMANATPPIQNVRSVGVNEFYLLGVARLCLIVVGEGAPGTTK"
     gene            4549..4761
                     /locus_tag="PK063_04085"
     CDS             4549..4761
                     /locus_tag="PK063_04085"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96253.1"
                     /translation="MRLRYTLGFLFGVLLLSASCDQGSKPADKSTPPSNAAPTSSNLK
                     ETHPDQPTGLPQSGEGKQVPTKRREA"
     gene            5301..5762
                     /locus_tag="PK063_04090"
     CDS             5301..5762
                     /locus_tag="PK063_04090"
                     /inference="COORDINATES: protein motif:HMM:NF039411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6335 family protein"
                     /protein_id="HMZ96254.1"
                     /translation="MERKRKKVVTDADQQIRNYYEHQPPSETEAFPDLSETIPTSEQL
                     MGKVGHMEQDRSGLNGADPDVSPQGIDAGTETPGGSEPTPDQDLVDEIGKAAGVTYQD
                     DEPLNFDEKIAAHDEARWELNPASSEDFEERQSELRGKMPSRRIRNGEENS"
     gene            5884..6399
                     /locus_tag="PK063_04095"
     CDS             5884..6399
                     /locus_tag="PK063_04095"
                     /inference="COORDINATES: protein motif:HMM:NF015331.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SRPBCC family protein"
                     /protein_id="HMZ96255.1"
                     /translation="MIFLGRRMTVRWSGEGKEQAMALIEKSIEVNVPVRTTYNQWTQF
                     EEFPKFMEGVTQVQQVDSTHLHWKAQIAGKEKEWNAVITEQRPDARIAWKSTDGAKNA
                     GVVTFHRLSDQKSKVMLQMDYEPEGVVENIGEVIGAVSLRVEGDLSRFKEFIERRGHE
                     SGAWRGEVKGK"
     gene            6780..8105
                     /locus_tag="PK063_04100"
     CDS             6780..8105
                     /locus_tag="PK063_04100"
                     /inference="COORDINATES: protein motif:HMM:NF024627.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HMZ96256.1"
                     /translation="MTAFTVLLLLFLIRPVHAADYYLTATGDDRDTGLSSDHAWRTLD
                     RVNQLELLAGDRILLEAGTTFLGPLLLDGADRGTESAPITVTTFGNGPAVIEAGEGMG
                     IFVRSTAGVILSNLHVSGNHHPHNNSDGIAIHNDLDGALLLTGITIDHVEVSGFGKNG
                     ISIGGWNGDSGFRNVRVTHTRIHDNGLNGLVTYAQHPRANKDVYIAYVEAYRNTGLPG
                     VVPHSGSGIILGNVENGVIEWSKAYENGRLGNAGVGIWTYDSTKVVIQHNESFANRTS
                     GEADGGGFDLDGGVTDSVMQHNFSHDNDGAGYGLYEYAEAPPWYGNTVRHNLSVNDGR
                     KNGAAGIQIWNGGTSLLADATIHDNIVMMGPSEDVTPSAIAFKSPSQGFSIYQNAFIA
                     SGEAILVFKPAEQVHLHMSDNRCWSMTTRSLWDESLEREVCAIYFRFPG"
     gene            8315..10954
                     /locus_tag="PK063_04105"
     CDS             8315..10954
                     /locus_tag="PK063_04105"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF025025.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HMZ96257.1"
                     /translation="MDSPIKVLDVDLAHPLQDLGGLDPYRSVWGLLRLNGRPVGDVTV
                     PIRDGVCTAESMYEAIVLQQGRPILQALIAHHLHDPVSRAGIRTLDPIGMDDMPANVW
                     PLVTVAVCTRDRSEGLHTCLHALQKLDYPSLDRVVIDNAPQSDRTERLVREEFPAVRY
                     VREPRPGLDWARNRALAVARGDIVAFTDDDVIVDQRWVRTLAEVFVRHPEVMAVTGLV
                     VPAELETRAQILFETYGGFGRGFEQRWYRAHSTKPQVDTFHLGAGVFGTGANMAYRRA
                     LFKNLNGFDPALDVGTVTNGGGDLEMFFRVLQEGYVLVYEPRALVRHRHRRTYQELAT
                     QLTNHGVGLYSCLSRCVRAYPALRPAGVCFGARWFWSWNIRRLLVSYVRRSSLPRDLM
                     VAELRGSLRGLFAYQTARRTARRLRDLQAGTGERAEEDMFLKLSSDLSHSPTGQPGKA
                     SCSLLPKPQFPIAVRAVELSEPLSDIGDLEKYKALQLYVTLHGELLGKHTIEHTAGIV
                     PVAQLRQAIAKSFGIRLLSRDTHHLGDAPWNRIIADLVERSPIPNPQPPKLSAGSRVS
                     IVIATLDRPEELRHCLGALSRQESSRQVEIIVVDNNPASGLTQTILKEFPAVVSVQQA
                     RRGLSYARNSGIVKSSGEIIIMIDDDVTVSSTWLERLIGHFSRPDVMAVTGNVLPLEL
                     DTEPQVLFETYGGLGRGFERLDVNGSWLRAFYSAPRTWVLGATANAAFRASVFRDEHI
                     GLLDEALGAGMAGVGEDTYLFYRILRANHRLVYEPSAYVWHKHRRDIRAFRRQLFAYS
                     KGHVAYHLTTLFRDGDLRVLLYLFVSLPRAYLFRAKSRLLGRTVYPLSLLLLEILGNL
                     IGPWTYVACRWKASRHSAERVSR"
     gene            10951..12954
                     /locus_tag="PK063_04110"
     CDS             10951..12954
                     /locus_tag="PK063_04110"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96258.1"
                     /translation="MTAHNIPAVDSLPHREEPSTDQISADFRMLLGAVDVVSFDLFDT
                     LIQRDALFCPKDLFYRVQAVVEHRHAITLKDFVSTRVRAESIARVRARGRQSEETTLE
                     DIYVEMANILSLPSSFAEEMLHIELECERAALMALPDGKRLYDAAIRAGKTTVVISDT
                     YLSRVFLEEILMKAGFNGVHRVYASSEFGKTKHHGALFGIVLKDLKCSPGRLLHVGDN
                     PLSDATAALGQGLRSFICTNPKQRLKWRYGLSDRPSGSQAISALLCDISRTAEEQSHG
                     TTDRAVIARSAVEHLSWVYEGFAAWLVHQMASQRDTRVYFASRDGLIMKKFFDVTRKA
                     FGTPIESRYLYVSRAALYPMLVLTDPDMARRLFCHSWDHLTMTQALKRMSLVPQEVAG
                     QLAKYGLADPLLSLNRVTTLKLSRFLDAIWPLLCAKSESHCELVAEYLRQEGFLADEP
                     TAFVDIGWHASLQHCLVKLLQHRGFKNTLHGYYLGTFARPDASPEVSAKGFLIENDAP
                     ASISALIRTGPSLLELFHAAGHGSVLGYERKDGRVVPVLEENEREQEQFRRIIEPLQQ
                     HAFEFVAARLARGDKPEASTFPPELVARLGLRILHKPTDEEAEIFGRLRIATDFGGSM
                     KSLTGACEWNLSEVVGDALPDGIPPMWYPGFYALKKSATKRAS"
     gene            12966..14498
                     /locus_tag="PK063_04115"
     CDS             12966..14498
                     /locus_tag="PK063_04115"
                     /inference="COORDINATES: protein motif:HMM:NF025025.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional class I SAM-dependent
                     methyltransferase/glycosyltransferase family 2 protein"
                     /protein_id="HMZ96259.1"
                     /translation="MDDLRDTRIDTLALREKYRDQYFLHRDPIYQDRLLWRAHTFRHI
                     MHLLPTQSILELGCGRGLFTPHLCRVSRGENPVTSVTFRAQQARPDSLSADVEFLYIS
                     ALPGPLRGKHYDFIVAIDLLDQRNCGWFLQQIYELLRPGGQVLFYESNPWNLALRAKH
                     CWRRLRGGDDPRRLLNRPVLYELMSEVGFIRVFALYNDFVYAPLTRSLIWFLRNMSIL
                     LENARGIQTFAGSILLHAQKPPRTTVRPLRSLCEHAQLHRAISVVIPCHNEEMNVEPL
                     VTQLMALYGDYIHEIIPVDDNSTDRTAEVLRRLAGAEPRVKPVFRTPPNGVGRALADG
                     YRVATGQYVLSMDCDFQHLLPEIRDLFDAAAQGYDVVIGSRFSRHSVLLNYPFKKILA
                     NRAFHALGQILFLRQFRDLTNNLKLMRREVVERLQLTQPHFAVNAETGLQPLLMGYSL
                     REVPISWINRTPDMGSSSFHLGKVGRGYMAVLFRLWWKHLAGAIAVPLKMKSSNSESS
                     LR"
     gene            14504..16693
                     /locus_tag="PK063_04120"
     CDS             14504..16693
                     /locus_tag="PK063_04120"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96260.1"
                     /translation="MAVTHDEPASMLKQEDFVFTNSSLSQEPANTPVWRSDRSVRVFV
                     LSIWLGMVMLAMVNWAEGSRNVPFSEDWLLVSALMGHEPYLGTWLWSQHNEHRVPVPR
                     LILLALLTVGQGDFRIGGAFNILALGGVSLLMMETARSVRGGSSRVADAFFPVAFLHL
                     GHTENMLWTWQITQVLPVILVSALMLIVVAGRIPRTTASTLAAGVCTIMLPLCGANGL
                     LYAPLFAFWIGYVGIVIIAGRSNEHIAGENWKGRYLVGAAAVTLLLSGLYFVQYHPPQ
                     YGAEAPTLPGALYATLQFIALSVGPAARMSWVLSIAAVMVCLVPALVIGARHFVARQD
                     RNPFRPVGVVVCAANLLLSALAIGWGRAQVLSLWGGLWPIRYSLFAVPILCLAYFVYE
                     LYGSTWTRQAFQTLLFVGMVLLVPANATQGARWHDWYLQGAGAFERDVQSGASVSRVG
                     ERNREYLYRWMDPSFDKVRMLRDSGIGPFAKMAEEPSAPVQAPRHQGMPESPVAESLP
                     AARRELRFVMPEAAEVFLVWGINGWQAAPESFRPAGTVVKDHVLHTPMHRQDGVFVMP
                     LALPRGASLDYCFLITKKREAFDITWPLCEGNYHEEFMADGVREIRSRTSLALVRQEI
                     RYHAPEAKEVHLVWGVKGWHVTPQSLWPSGTAIIDHVMHTPMALREGIFVATVTVPVD
                     TAVDYGFQITKRRGIFDLVYPLFDGNYSVRPSQDGQIDMQAKPGLIP"
     gene            16781..20491
                     /locus_tag="PK063_04125"
     CDS             16781..20491
                     /locus_tag="PK063_04125"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF025025.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HMZ96261.1"
                     /translation="MNDSPIAEPSAKTMVFIVPSLSRSSAQDEDVVQLLLCAAARVEQ
                     LLSASPGLVVKATILSVDQDLSGWVQVGALFSDRISKHVTVEPLKEPATPCLAIPAHK
                     SVYHVHEFLRERPFDEVHCLDRHGYVYYSAHAKRLGLFFLTTLFCVHVVGGTIFRREC
                     QDLLLDDPDILAIDLLERGTVERADLHYIHDIKAWEWYDEKVVLHAGSTSYDVTWPVD
                     PPTSVVVEGNESSELPALIYCGPLGADGGLPLFCDVVDRLVSQGERLKHVTFVGAAHA
                     IGGVDAVTYIRLRSSGWHLPITIKRDLSLADEMTFLAGLQGVVVCHTARRNHLRSRLI
                     VGGLQNVLHIRAVNESRDGARSGGVLPGQITQTVTRLLRAPLQQSPVSLPPLTQLWKA
                     GRKLPDHEGVRSSLPLGVPNEPQPRVSVCITHFSRPQKLRMALQSLKQQTYRNFDVIV
                     VDDGSPDPDVQKELALIGDEIRPLGWRILFQENRYLGAARNVGARHATGEFLLFMDDD
                     NVAKPHELSTFVAMAQRTGADIITSFFDVFETEATLESDGPPPLRFTPYGADPALGIF
                     TNCYGDANALYSRRAFDKLGGFTEDFGVTHEDWELFCRASLEGVTLLCIPEPLFWYRM
                     DQSAMFRGSRTQLHKSTNLRRHIRPYLEKLPRYQSNLVQLLQGLSTTLPLTTVGTVSR
                     NAAPLALRQPDATLPYGRVAVITRTKDRPLLLHRAIRSVLSQTFKDWVLVIVNDGGDP
                     QRLEKVVDEVREELADRILVVHHPMPLGMQAASNSGIAHCDSDFVIIHDDDDSWDPTF
                     LARTVSYLDDHGWNARLGGVITWSWVIIEEVADDGAVKVHNRFVFNDKLHNVALIDMT
                     VENRFPPISFLFRRAAMDHVGPFRSQHGPLGDWEFHLRLLQHFDVDVIPDPLANYHHR
                     TNTTIGIYGNSVHAHKDQHQASRIHLLNEALRRDLDSGQGLSLAQLLTLGELHHSSKA
                     EQAREFQRLHDYLWNIDQRVQAIATQVHSSKHGLRAKSRRNLVSNGDFRQWPGLGPNQ
                     FGPHETYTFLDVSPGCVLCYDGRQVSYRLEQRKWTTDGQQLAFGKTFLHIENDGYTKG
                     GSWFAIEFMIPSALLLSGHTITISGVSRLNALQGWIGLGGRYLFGDGRQLDWPDHRID
                     VASDFARWTCTVMCPAIQETEVGHGHQSRILLKLPHNQPFDFDLTNLQVELGSESSDF
                     EYSSGKVSLRHRVHLVLRGLKRRLRAAKRAIG"
     gene            20532..21287
                     /locus_tag="PK063_04130"
     CDS             20532..21287
                     /locus_tag="PK063_04130"
                     /inference="COORDINATES: protein motif:HMM:NF013245.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HMZ96262.1"
                     /translation="MSGISWNLIRHLVARDFRIRYSGSVLGVVWSVLIPMAQLGVLVF
                     TFGSVVPVNIDDYPAFVYSALLPWTWFSACLGSTGSLFFSHRDLVRRPNFQPIILTVV
                     NTLSNLVTFLLSLPLLFLLLAWYQRSVAASLVALPALLVLQAVMTVGLSLLVSTWNVF
                     YRDVSQLVNIVLSLLFFLTPIFYRPVVESKYAMIFQFNPLAVLISSYRNILFEGRLPE
                     WDAWAHITAVSAALLVCGYLVYRHELPDVVDTV"
     gene            21297..22553
                     /locus_tag="PK063_04135"
     CDS             21297..22553
                     /locus_tag="PK063_04135"
                     /inference="COORDINATES: protein motif:HMM:NF025877.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ96263.1"
                     /translation="MHAAMTVTDLSKRYRISRHKVTTLRETVDRWIKGRQDVTRTMWA
                     LRDVSFTIEQGRVFGIIGHNGAGKSTLLRLLCGLGRPTSGRIEAGGYVSGILELGGGF
                     HAELTGRQNLMTVGILNGLTPAEVKAREQDIIAFSELEDFIDQAVRTYSNGMYLRLAF
                     AAAIEFDPAILIIDEVLSVGDERFQQKCLDRIAAFRASGKTLVITSHDTDQIQRLCDE
                     VLVLEEGRAIMQGDPKSAIACYHDLMRQRTERRAAHIGGGSTRSLTTASGTRQGTQEA
                     TIAVVRLCRSDGQAVETIRSGEGILAELEIDAPPSIEDFALTVGVFNEGHVKCFEATI
                     ASVQGTLGKVSPHSSIQCHLKHLPLLSGSYFINVGIYPTDWSYVYDFHWQMHPVTVFD
                     ERTSNSQAGGIVAVETHWTIISRGDV"
     gene            22550..24457
                     /locus_tag="PK063_04140"
     CDS             22550..24457
                     /locus_tag="PK063_04140"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96264.1"
                     /translation="MRPAIRAAGLVCCCVIMPLWHVVQVGAETTTAPASPPRMLTREI
                     RYHMPEAGEVWLVWGVNGWHRLPEAAWPPGTVLGKTGLMTTRMIEQGDAFVATVAVPN
                     GTALDYCFLLTKKREAFDITWPLCEGNYSEVATRSGVTEIGSRLSLAVVTQEFHYHMP
                     DAQEVSMVWGVNGWSPVPESLRPLNTKMSDNLMVSPMRKREQEFIVSVQVPVGATIDF
                     GFRITRSAMGSVNIWEGGGAEGFHEPVRGGSSIRVKSNAIILPRGRPSRDEDNGWHVA
                     WAIVGAVSAPLLLAGLLVMLRRRQARQRSANPFNPRREKPSSALDGLLILAAVGIGAF
                     GAEQMLRNVYPHEGFGIAAEDEWFRQAPYSANQLFTIDPTLGIRPWLRTGRYTEYGTV
                     PNMYRLAKDSRHTRILFVGNTVTYEGTLLHALRELHGEDRFEYWNAGVPTFNTVQQIA
                     YYHAYNARTAPDHVILTIQPDDLGTIPIVFRNHTAELEVHRPAIPRKDLDTELYGSSY
                     LYRYVKGLLISPEEKLHRLWQEYRDSVKSFSERLAHDHIRLSVVVLPVLASQQEWTQA
                     ERDRRQALFSVLTELQIEHYDLAQAFEPGRAENAVLPPMSKESWAPSSEMVSAFAQYM
                     THEGLFRTKEH"
     gene            24459..25460
                     /locus_tag="PK063_04145"
     CDS             24459..25460
                     /locus_tag="PK063_04145"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF021616.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HMZ96265.1"
                     /translation="MSPHHTHRHENRARSNHADESTHDVQRGDSSESISGLVSIVIPC
                     YQQAHFLPDAISSILRQTYPDIEIIVVDDGSTDHTRDVALSHPGIRYIAQKNAGVSSA
                     RNTGFRMSRGEYIVFLDADDRLIADAIEIGTRSLAEHPACALTFGTFFMIDAEGTRHN
                     PSYPLNAVTYGYKELLEENAIGNPGVALYRRWALSVVGGFDHRNGPAGDYDLYLRIAR
                     LFPVACHRRPVIEYRRHGGNMSNDPGVMLKACLSALNKQRAFIKNQPDLTLAMRRGRI
                     GWKLYYGEPLVSKVQDEFSNRNWKEGLRGLLQLAIWYPERFLTGLSRKATKLKNRMR"
     gene            25492..26121
                     /locus_tag="PK063_04150"
     CDS             25492..26121
                     /locus_tag="PK063_04150"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96266.1"
                     /translation="MKSCPPKSAWRSRLALMVVLCGLPGCVTDAPTLTESPDEGRKVL
                     LMGNVVTVLTGDRARKFEPAVRDIELIEQNAGTRYRVQVDGPDKPFAVFVPPGRYDIT
                     RVKIHEGPFLSIAHLTASFSVEEGSPIFVGTWRFGVDSPRYGRMVAVSMVLDDEARQQ
                     AEQELRETYPDLVSPRMLTVLPAPSELQTRLYEVAPYPRISRYFRRHYW"
     gene            complement(26179..27168)
                     /locus_tag="PK063_04155"
     CDS             complement(26179..27168)
                     /locus_tag="PK063_04155"
                     /EC_number="6.5.1.1"
                     /inference="COORDINATES: protein motif:HMM:NF006078.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003910 - DNA ligase (ATP) activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA ligase"
                     /protein_id="HMZ96267.1"
                     /translation="MAAPTFAPMEALLVSRLPEGHEWRYEPKWDGFRCLAYKRKTSVT
                     LHSKSGKPLDRYFPDIVRVLAKLKADNFVLDGELLIKGEEGYSFTDLQMRLHPAASRV
                     TMLAKKQPATFVLFDILEAETDSAVMSAPFAARRLRLESFYARYCAKEPALQLSPQTA
                     SIAEAMAWLKSTGWYIDGIVAKHTLAAYEPGERVMQKYKPIRTADCVVGGFRYGSGSE
                     EVGSLLLGLYDKNGRLNHVGFTSGIAKADKPSLTKTLEALVHEPGFDGKAPGGPSRWS
                     TERSTTWTPLSPQIVVEVSFDHVTDDRFRHGTKLLRFRPDKAPRQCTMEQLRR"
     gene            complement(27173..28066)
                     /gene="ligD"
                     /locus_tag="PK063_04160"
     CDS             complement(27173..28066)
                     /gene="ligD"
                     /locus_tag="PK063_04160"
                     /EC_number="6.5.1.1"
                     /inference="COORDINATES: protein motif:HMM:TIGR02778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-homologous end-joining DNA ligase"
                     /protein_id="HMZ96268.1"
                     /translation="MKNHPGEALILHGVTITHPDRVVYKEERICKGDVARYYAAVAPF
                     LLRDITRRPISLLRCPSGIQADCFYQRNVGSGLGGHVHPFAWDYKGQSYQYIYVTDEM
                     GLMQMIQMGVIEIHPWGATIDSIHTPDRMIFDLDPDPTVPFSAVKQAATEIRQRLTKS
                     GLTSLLKCTGGKGLHVVVPLSPTRRWDEVKGWASTLAHAMVEEAPDRFVATMTKSKRA
                     GKIFIDYFRNDYTATSIAAYSLRARPGAPVAVPLQWRDLGTLKSADQFGMTAVLKRIA
                     RQQRPKPLPIQQLPVLKTERF"
     gene            28288..28779
                     /locus_tag="PK063_04165"
     CDS             28288..28779
                     /locus_tag="PK063_04165"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96269.1"
                     /translation="MAKDLDIQDDLPFQYRHWRLQRVGWWAIACILSAGLLGLFGHHP
                     LSRTTVQTQDGTLLVTYDRFGRATSDAEVLITVTPAKQEEGAFRVWFDSEYLDAVRVG
                     SVSPLPLRGEARQGGRAFVIQSDGGPSTVLFSVQFHTFGIIRGHVKINDGKAVPITHL
                     VWP"
     gene            28791..29240
                     /locus_tag="PK063_04170"
     CDS             28791..29240
                     /locus_tag="PK063_04170"
                     /inference="COORDINATES: protein motif:HMM:NF016154.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HMZ96270.1"
                     /translation="MDAILRGFIMYLFLLVLFRIAGRRTLGQMTNFDFVLLLIISEAT
                     QNAMIGNDFSVTNGILVILSLVGLDIGFSILKQRFPILNRHLDGLPLVLVDQGRPVQE
                     LMRKTRVDEEDILFSAREKHGLERMEQIKYAVLETNGGISIIPKSAE"
     gene            29346..29573
                     /locus_tag="PK063_04175"
     CDS             29346..29573
                     /locus_tag="PK063_04175"
                     /inference="COORDINATES: protein motif:HMM:NF016836.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BON domain-containing protein"
                     /protein_id="HMZ96271.1"
                     /translation="MGLDYAADDELASRIDQALLATDELNLSRIEVSVEPGVIYLSGI
                     SDDHDSKVQAEQAAQAYAEGRKIVNKIEVDF"
     gene            29723..30817
                     /locus_tag="PK063_04180"
     CDS             29723..30817
                     /locus_tag="PK063_04180"
                     /inference="COORDINATES: protein motif:HMM:NF019268.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HMZ96272.1"
                     /translation="MYEDQGGAVELWQYGGFADVSYASTGYHPENHQWRSKETSTRTN
                     ELAPNIGLLYVRKDPAEQSRWGVELAFQAGYDTDDLVPEPKADGTRPVSGADTLRHVA
                     RANVSYLAPIGRGVTFSAGLMKGSKTYEEFYAKYNLNYTRAYITDYNPNFVMGLGASY
                     PITKSLELGVYVINAYRHLAHTNDAPSYLSKMEWRVSDHLTVYENLYYGPDQRATSVD
                     YWRTFSDSTVEWRKPDWRVALSYNVGTEKMADVSGSPRAVWMGAALFTQRHLVGPWSI
                     AVRPECYWDPQGRMTEHEQLLWANTTTLEYKKHLGQQLIIVRLEHRYDRSTGSQGGFF
                     RDGFSAPGVPRLAADQHLTILGVILAFDSA"
     gene            31035..31370
                     /locus_tag="PK063_04185"
     CDS             31035..31370
                     /locus_tag="PK063_04185"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96273.1"
                     /translation="MSMIVLRCPASRLPKVLILLLTWVVVAGLSWADLVGSQAEPTGA
                     LVDAQVATELDLDELRDDGTAISLTEEELPARLSPRTPPFFQIGIPSPDDHSLPTRLL
                     LSKLSVYRL"
     gene            31499..34624
                     /locus_tag="PK063_04190"
     CDS             31499..34624
                     /locus_tag="PK063_04190"
                     /inference="COORDINATES: protein motif:HMM:TIGR00914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051139 - metal cation:proton antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CusA/CzcA family heavy metal efflux RND
                     transporter"
                     /protein_id="HMZ96274.1"
                     /translation="MIDRIVGAALAQRLMVCFAGLALLFGGLYAFHILDVVAYPDPSP
                     PMIEVITQYPGWSGEQMERAITLPIEIALQGMPGLSEIRSLSIFGLSDVKVYFDFGTD
                     YFRDRQEILNRLQLTVLPQNVQPTISPWSAIAEIFRYELTGDHVSLTDLKTTQDWQIR
                     REFKRVPGVIDVSTYGGTTKEYHVELDPGQLMSYNVTLDQVMDGLAKSNTDVGGNYLS
                     MGEQSFNIRGMGLIKKLEDISNTVVTQKEGTPVFVRNLGKTSIGSRVRLGKVGIDDRD
                     DVVEGVVLLQRGAKALPVLDKVHEKVQELNARKLPQGVAIKTFYDRTVLIHTTIETVI
                     DILIAGVVLVSIILYVFLGHFRTAMIVALTVPVALLFTFGMMVLSGQSANLISLGAVD
                     FGIIVDSTLIMVESIFYHLAHKSSAGVTVPMHVMRAAREVGRPIFFATTIIVIAFLPL
                     FTMTGVPGKVFAPMSLTYGFALTGALLMAFTLAPALCSLLLTGPIKERDTAVVEFLSR
                     RYMALLNWGLQREWLVIGIAIVTLVLAMAAVPFIGGEFMPALEEGNIWMRTTFPVDIS
                     FEQAARLVTDIRGIFRQFPEVISAASQLGRPDDGTDPTSFFNAEFLVTLKPFKEWRAD
                     VPTKKALVDQIEQRLAVIPGVTFNFSQAIQDNVQEAMSGVKGENAVKLYGSDLQTLEQ
                     LAAQIELVMKDVHGVKDLGVLHLLGQPNLVIEVNREECARYGLKVGDVNDVVQAAIGG
                     QAVTQIYEGERWFDLVVRFLPEFRRDIESIGNIVVSTPDGARIPLKQLASITEQTGAF
                     IVYRENNERYIPIKFSVRGRDLEGTVREAQERIEQQVPLPAGYRIEWHGEFDQLQEEK
                     ARLAKIVPITLLLILFLVYLVLNNVRDAFLVLAAVPFSLVGGVLALLVTGTHFSISAA
                     VGFISLFGVAVQGALILISRMQELLREGYEIRDAIIKSAEVRMRPVLMTSLAAAIGLL
                     PAAIATGIGAQSQQPLARVVVGGMLTSAALILLVLPVLYQLLHRYRKPSRSTGATASA
                     GTANQGHGSHE"
     gene            complement(34677..35279)
                     /locus_tag="PK063_04195"
     CDS             complement(34677..35279)
                     /locus_tag="PK063_04195"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class GN sortase"
                     /protein_id="HMZ96275.1"
                     /translation="MTGTWHRSRPVVWLMASLLAIGLWQVWEGSWMYAKAGLAQLLLQ
                     RAWTRSVEGEAMPKPWPWADTWPVARLRIPRLSVDLIVLAGAHGRTLAFGPGHVGSSA
                     LPGQTGTMMLAGHRDTHFQFLKELQPDDRLEIVGTDGTTRRYRVTERQVMDSQRDSIA
                     TSDERAELILVTCFPFDAITTGGPLRFVVRADAIPQADRS"
     gene            complement(35276..37333)
                     /locus_tag="PK063_04200"
     CDS             complement(35276..37333)
                     /locus_tag="PK063_04200"
                     /inference="COORDINATES: protein motif:HMM:TIGR03788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="marine proteobacterial sortase target protein"
                     /protein_id="HMZ96276.1"
                     /translation="MALATSGVGTPPTDAGSAESPVTLSTGVVPTMGINEVTEGTLLF
                     RTDQAGRFTPAPVLKTDVHIAVTGTIARATVRQEFTNPSTRKGDWLEGIYVFPLPETA
                     AVDHLRMHVGERIIEGQIKERAVAKKVYEQAKQQGQRTSLLDQERPNIFTTSVANIGP
                     GEHITIEIEYQETVRYDDEQFHLRFPMAVGQRYIPGTPVIIEGQAATGSGTMLDTDRV
                     PDASRITPPMQSPRYGAINPLSLSLTLHPGFPIDKVESSFHPIISIPDAEGGYHVTLR
                     ADAVPADRDFQLSWHPVARTEPIATVFTEQKNGQTYAMLMLAPPTQHDEKAPRVPRDL
                     TFIIDTSGSMAGPSIDQAKRALAAALPRLSMQDRFNIIQFNHTVRSLFAVPQPVTTTT
                     IKQAIRYTEHLSADGGTEVLPALRQALKSPQESARLQQIILLTDGQVGNEEELFELLH
                     QRVGTRRLFTIGIGSTPNSHLMRKAAEFGRGTFTYIGKVEEVEQKLERLFRKLERPVL
                     TDVSVDQAGWSGLEQYPATVADLYEGEPIVLAMKADAVPSHATLHGQVGSRPWSLPVS
                     LNQTATQGGLSVYWARQKISSLMDEATKEGRAEVTKTSVIEVALAHHLVSQYTSLVAV
                     DVTPARPTDVPGAEPGQTTNLANMQLSALPKTATGWQLQLLLGLSALVLAALVRRLRN
                     EVA"
     gene            complement(37492..38310)
                     /locus_tag="PK063_04205"
     CDS             complement(37492..38310)
                     /locus_tag="PK063_04205"
                     /inference="COORDINATES: protein motif:HMM:NF012894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HMZ96277.1"
                     /translation="MQKSPIATVSAGPVAPTLVGPDRDMKDVYILSGLVGFLAIVVAA
                     FWYYSQADEAAHSNRSSEALDVAQVSQVLKESTEKVTGGAAMPVTHVETIPLASRSTE
                     ILHDDIQFEVGRKGLTDDGKASLQRHAEFLKNEPDWGVLLQGYTDQQGSMSFNKILGM
                     KRAETVKQQLISLGVPESAIRTVSLGEEGALCIDKSDACRQMNRRVHLEMRKIGQEHM
                     VIPAVITEPVTDSFSLTTDLSMESASAESDSENPTGVGASSNGADSPVESATGN"
     gene            38962..39768
                     /locus_tag="PK063_04210"
     CDS             38962..39768
                     /locus_tag="PK063_04210"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96278.1"
                     /translation="MKRLSSWLLMSWLLMGSLVQAADYQLTLGQGIDVCEACKQNLER
                     MTVHPACEREYSAQFDLESPAWKPFDVAGHLEAMEQVLYFLTAGSESGRNIPDESRFE
                     DTLWRISTKDEPWAYWAQVDINNDGKAEPVLKLHSSLCHARNDGSIGRAYSAPIVVLT
                     ENLSGIDHELTDLVLQNPRQDGRAAGETNYQLYGVFRYKGTTYFDRWDDAGSGDQADQ
                     FTLSIYASTGDTTRKLCRLKELQAKRWFPGLPCTSRQCQTARPLPAHYIP"
     gene            complement(39804..40925)
                     /locus_tag="PK063_04215"
     CDS             complement(39804..40925)
                     /locus_tag="PK063_04215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HMZ96279.1"
                     /translation="MTEPAQVTWTEEGQSYAAHWRSEWGAPPPKRVVIADDRMTADAA
                     HRLACEGTALLWRGDFQNARQLLLAMARRADRHPPKPGASPTESFHFHRQTQARRARI
                     LGMLLITLEDDYAIRLRRAPDLREACTEAYGPATARALVSLRELLGVIGAHEWRKNGI
                     DIPALGDRIHPHYGVFSPIRSEYVALVADAPLPACTLAFDIGTGTGVLAAILARRGVP
                     RIIATDQDPRALACARENLQRLELSDQVEVRQANLFPEGKAQLVVCNPPWVPARPTSP
                     LEQAIYDPENRMLYGLLNGLAAHLEPGGEGWLLLSDLAEHLALRSRKELLATFEQAGL
                     VVAGKTDIRPTHPRASEQADPLRAARAAELTSLWRLKSR"
     gene            complement(41028..43730)
                     /locus_tag="PK063_04220"
     CDS             complement(41028..43730)
                     /locus_tag="PK063_04220"
                     /inference="COORDINATES: protein motif:HMM:NF017076.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HMZ96280.1"
                     /translation="MRIATRLFVRNIWLQAAVMTLAAIVLSDILWTPAPATRQALEWA
                     PYDTWMRLRVQAAPDPNLLLIVRDRASDQQFGTGSWDRALPARLITALHDAGAASIGL
                     DIPLELPSPPNLGGAVSDALLMEAVKSAGTVSYPAIGVAVSDQEAAALSSHFTPGRSA
                     LHPTFDPDRVVRRLPLYHGDGPGELPALGFSLATTFWQVQSNQLERRSGRIHLHNARV
                     AGGSTGDIDIPVDRYGRLLINVAGHPLPTVFPTLSVLDLTRMIDRKENEGLSALVNGK
                     AVLFLTQPTPQPERMMPTGEEAPDMLLQAHLLHTLLTQDWIRDLSPLQRAIVTFALGL
                     STAWGVLRWTDWKGPVLGASMLVLYFFVSWAMLATAHWVLPFIIPVTTSVMILVVGSL
                     LGQMMATRRLVLLEQDMLLVQQNLVAVREALIYRETAVESLEEDLESARASMSHSVSK
                     EAESSRLAAELQLKIAEAQAQEDATRQRMAALEQQLQGMRAATITAEPLGNVEQDALR
                     RECEQAGMITRNPAILTMFRDLKKGARTTVTVLITGEAGTGKELCARAIHRLSPRAAK
                     PFIAVNMAAISPELFESELFGHVRGSFTGAHADRKGYFELAHLGTIFLDEIGDLRLDH
                     QSKLLRVLQDRSFYRVGATTPTTVDVRIVAATNKDLQRGVSEGWFREDLYFRLKGLVL
                     DLPPLRERRDDIPLIAEAYLHEAANHNHQSSMRLSEEAVSTLMQQSWPGNVRELRQCL
                     EQAMALSDSPILSAADLRLSGPASPRTGTSGAAPLLPNPAGDLAVLQQLRQQRFDMQA
                     TAKALGWDRSTVTQRLKGLCFQALVDASGDQAKAAASLAGDPSLLRTVELKLMDYYGH
                     LMETIAPFTNVDDALLDCKRRFKNLPERHFKSVEVLVRRHFSAA"
     gene            complement(43771..45114)
                     /locus_tag="PK063_04225"
     CDS             complement(43771..45114)
                     /locus_tag="PK063_04225"
                     /inference="COORDINATES: protein motif:HMM:NF024824.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ96281.1"
                     /translation="MFLQRVSVGRWFLIATVALPLPSLPAGAQEEPSPAAATGTVQAE
                     TPVTETPAAPQADQAPQEAIRVEPLPSEPPAPPPPPPVAPPVQPPLTPLEILARARQA
                     LHIEPDAQEPRLTLGRTLFQLGDTDGAIDEYRTALRFHPTVAQAHLDLGTALMAKQDW
                     RTAMTELQEAVRLDPTLVQAHYSMGTIQYTRGNIQSAIKAYQEALRLKPDFAEAHYRL
                     GLVLKVAGKDKDAAQELEAAALAGLSKAQYFLGNAYRSGQGVEKSQIMAITWWAQAFE
                     QGLPEAAQALTQLRRLAAVKGNLQTKQSKAAAEAFKNYCDQIWLDFPDLDRDQPTETV
                     GTTLLKQGRTAEALPVLLREAYALNEMAHATLVQLYEQGLDGQLPPHGQWILSYLEST
                     AADGAVPSRLALARIYGKGLGLAPDQAKAKSYLKGLPKDDVKRILDDVAAEPPKP"
     gene            complement(45274..45936)
                     /locus_tag="PK063_04230"
     CDS             complement(45274..45936)
                     /locus_tag="PK063_04230"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96282.1"
                     /translation="MMQIPPGPNGSSPRTFFQTLIRTLPLHVLITTSIVGGAALFYSL
                     SVSNRGTWTMLGSWSLTALYILIGLVGGTVAGVLDASRQMVERLEQVLRDWLHTLPAL
                     NRSADTTGRDVSTVRQEYETLVDHSVAQAGRRLRLPQWLERLIRAGVRGLVVDRFIAS
                     CTARGIHVVAPQEFRNWMLAEGVSLGFMPVLDQLAWWRYLLLGVLTLLAAIALTLAFL
                     TT"
     gene            complement(45950..46399)
                     /locus_tag="PK063_04235"
     CDS             complement(45950..46399)
                     /locus_tag="PK063_04235"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF013401.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HMZ96283.1"
                     /translation="MSDHACKACVGTWPSQNHFIADCGLTKAYLHDDQFFPGWTVLVF
                     KRHATELFHLSREERSSLIEEVAQVSALLAEEWRAVKINYELLGNQLPHIHWHLIPRL
                     SQDPAPLEPVWRIAHEPVRPEPDALKSLVARLRAIWPAHRHQPPSSA"
     gene            complement(46396..47016)
                     /locus_tag="PK063_04240"
     CDS             complement(46396..47016)
                     /locus_tag="PK063_04240"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96284.1"
                     /translation="MRIPRSMQILAAGACLLLADTAAPVGASDQLVDVTGKVTPFVTL
                     RSRDNFSSEYRYDVTVRNSSPDLFVADSLILVLDHITNTAGQDRENLTGESLLTRMEI
                     IGQDGTTEDGKPYFRIPQGSGPDLTPNSESLPVTVRIRNRDYVAVFTPSFRVMGQRRE
                     PPKQKSQAAAAAAAAAPHKATTDKLIQLLLKKGLITAEEARTLLQP"
     gene            47177..48049
                     /locus_tag="PK063_04245"
     CDS             47177..48049
                     /locus_tag="PK063_04245"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96285.1"
                     /translation="MARTRTTSLPLLVPRAFASTLLRFYDYPDPRRPGRMIKGYDCPH
                     AVRTARMCAAVAQRLGHAPARVKQYQIACLLHDLGRAGLDRTLFGRIWSWARAHGIPT
                     RPREWRAAHPDTRYGKETEAFVARYRTAMETAGITLDPWACEQVEMRLGYARRLAGRL
                     RIVKPELRDLGVAWAPWMGRIMLYYYYPEKLAGAQPWVRQLAEILVACEQFEAFSNQR
                     RGRDYYVRRREDLAEAFAYLNGLQKEGIISRPVVQALRELSAEGVFDAVLEQARGRAL
                     SKRERAFLRQASKE"
     gene            48053..48475
                     /locus_tag="PK063_04250"
     CDS             48053..48475
                     /locus_tag="PK063_04250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="secondary thiamine-phosphate synthase enzyme
                     YjbQ"
                     /protein_id="HMZ96286.1"
                     /translation="MAVKTVTIRVPMQGDSRMENITAQVQAALEQTPLRAGIVTVFIK
                     HTTASVLIVEDEPGIRADTQVLWERLIPADPRWQHNERNAGEDNGHSHLRGQLQGQSL
                     TIPFTDGAMMLGMWQQIVVLDFDTRARTRELVLQIIGE"
     gene            48503..49603
                     /locus_tag="PK063_04255"
     CDS             48503..49603
                     /locus_tag="PK063_04255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HMZ96287.1"
                     /translation="MSVAWACGVGLLSSVLSGLFSPAGGIAAEATSPSLTAQVAAPTD
                     LSPEEQATIAVFDRATRSVVFIANTAMQRDPWSFNLFEVPQGSGTGFVWSRQGHIVTN
                     YHVIYGADSITVTLADRTEYKAKVIGADPDHDVAVLQIQASEATLQPVTIGNSQSLRV
                     GQKVLAIGNPFGLDHTLTTGVVSALGRTIKSMSNRTIEGVIQTDAAINPGNSGGPLLD
                     SGGRLIGVNTQIVSPSGAFAGIGFAVPVDTINRIVPELIKHGKLIRPGLGISLVPDAM
                     ARRWGVKGVIIGKVGRGSAAERIGLHGARETAGGRIELGDIIVAVDGKPVESIDDLMD
                     SMEQHKVGDQVTIEFARGNRRMQATATLQPVN"
     gene            49691..51442
                     /locus_tag="PK063_04260"
     CDS             49691..51442
                     /locus_tag="PK063_04260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HMZ96288.1"
                     /translation="MSDHRNADQPGHGGQPSPSRDASTPADPIELIDECLAAFPDGDP
                     RQKLLYKLRHVVTAQSVAQDRRDTELKKLNEVVAKLTAPANRVGLLVEVPAEGVARIV
                     VGGAEYYANIDPRLAAEELKIGAQILVNEAYTVIKALEYDRNGPVLKVAEILPDGRIR
                     FEQDMGRQALILQRSSDLLGVDLKAGDEVRIEPTHRIAIEKFENRQARTHLLDEVPNV
                     TWEQIGGQHQAIDAIRKAIEYPLLHADTFTKYQFTQPKGFLLYGPPGCGKTMIGQAAA
                     ASLSQLVRESHGQAASDGHTKNPPVTSGAFLHIKGPEILNMWLGESERIVRDLFAKAR
                     ARRKEGALPFIFIDEAESVLGTRRSMRSFNINNTLVPMFCAEMDGIESLQDVVIILAS
                     NRPDLIDPAVLRPGRIDRKIKVARPTREAAVEILSVYLTPALPLEPALLEQHDHSHDA
                     ARRAVIEQVVDSLFSRTDQNRVLSIRLRNGQNKVLYRGDLVSGAILSAIVQRAKEKAI
                     ERAVAQTGAAAGDGIRAQDLLDAVQEEYREGEMLPPDDAAEEWLKLLDHHPEQVVGVS
                     SFRRGRPTEERLVNQII"
     gene            51480..53003
                     /locus_tag="PK063_04265"
     CDS             51480..53003
                     /locus_tag="PK063_04265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proteasome accessory factor PafA2 family
                     protein"
                     /protein_id="HMZ96289.1"
                     /translation="MHLFGIETEYGITREDLDAVDPVEESMELVRAHLTGEFERRWDY
                     HGEDPHEDARGFRVSGLQQDKEEDDFAKVDAHRPYSFHEMKSDLVLPNGARFYNDHTH
                     PEYSTPECRTLKDLLAHDRAGERIVQRAADRRNQRLGGAHVQLYKNNTDFHGHSYGCH
                     DNYLVPRALPFPQLVQGLLPFLVSRQVIAGAGKVGMEAQESGFVPGPFQLSQRADFME
                     AELGVDTMHNRPILNTRDEPHADRAKYRRLHLIVGDANFCEYATALKVGTTRLVLDLL
                     QRGAAPLVELEQPVTAIKQLSRDPDLKTTVRLKDGRTISGLAIQQEYWNAASRVCGGS
                     DPDADWVLREWHDTLQCLGGDRTPLVGKLDWVTKQWLLETFMREEQLAWEDPWLASLD
                     LEYHNLNPDRGLFLGLEAEGKTWRMTTERDIAQALVAGPSDTRGGLRGLCVRRFPEQI
                     TGMQWERVQFAGGLRGRTLEMGDLFDPEAVQACAGLFETAASPADALAAWAKRKDAQ"
     gene            53000..53197
                     /locus_tag="PK063_04270"
     CDS             53000..53197
                     /locus_tag="PK063_04270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquitin-like protein UBact"
                     /protein_id="HMZ96290.1"
                     /translation="MMRYTMMPERREAPGDPMPKPTGPSEEGGGPRRPDTGSPDKDNL
                     LKRMRKVDPKQAERYRQRTGQ"
     gene            53253..54026
                     /locus_tag="PK063_04275"
     CDS             53253..54026
                     /locus_tag="PK063_04275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proteasome subunit alpha"
                     /protein_id="HMZ96291.1"
                     /translation="MGMQGDFFQLLKEQGYQFGNPSAAAAGLDIPNATTILALKYRDG
                     VLVAGDRRATAGNMVMYDRTDKVLEIDRHSVLAIAGVPATAYEMVRVLEHSFKYYRRT
                     QLQELSFEGKLRAVSKLLKENVPAALAGTGAVVPVFAGFDHEQEAAKIYFYDILGAEF
                     EAVEYAVSGSGSPTIRGILHYVNTWGPQPLAAMPEEQATVQALRLLSSAAEFDSATGG
                     VNRELNLYPVVKLITAAGVQTIPDTHLKHLYERDVVRAL"
     gene            54096..54920
                     /locus_tag="PK063_04280"
     CDS             54096..54920
                     /locus_tag="PK063_04280"
                     /inference="COORDINATES: protein motif:HMM:NF012452.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="20S proteasome subunit A/B"
                     /protein_id="HMZ96292.1"
                     /translation="MYEEPYRWIEAVGNRRQYLDEQFAMGAPVVALAYADGIVLLTVS
                     RGTPKLYEIYDRIALGGMGHPADLEKLRFSLLEMAHVEGFNRSPSDVTGARLMKYGLA
                     PAIKQAFEEIYKAPFIAKILLAELGVKPERDLFLTINYDGNFEERRGWAALGATSAVQ
                     VQMGRYIDAQPGFAQASLAQAVETGLCAWAVGSLAQTSSGTSDGDSSVRDAAEKPDAE
                     ALPDKTALLAHVRQTVAEKSLECVLLERNGPGSSKYRTLRPDELGRVLPSAVRASQ"
     gene            55000..56490
                     /locus_tag="PK063_04285"
     CDS             55000..56490
                     /locus_tag="PK063_04285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proteasome accessory factor PafA2 family
                     protein"
                     /protein_id="HMZ96293.1"
                     /translation="MLNRIFGIETEYGLLVNQDRPDHSPSWVAQRIRDHIFHIARRGV
                     LDLHHRGHDEPPGNGGFLTNAGRIYIDMGHLEYASPECTTLADLVASDRAGDRIIQQA
                     VTALGLDETVSLIKNNIDHETDATFGSHENYLVTRQFPFSRRGLGPLVTFLVTRQVFT
                     GAGRIGCAGDPNEWVQIGGLILHRPGLRDAQDRSIVPFQISQRADYIVNDFFEWVQHN
                     RAIVNTRDEPLADPNQYRRIHLLCGDSNMAEYATALKMGTTGLVLQLIEAGQAPRGLS
                     ISEPVEALQDISRDPDRQWIVRLESGQSISALDIQEQFLAAAQRHCKGQDEETDWVLE
                     QWESVLTDLRHGYEKLVGRIDWASKLWLLETYREAEQLAWDDPMLKSLDLEYHNLHPE
                     RGLCYGLEEEGRGPRLTTDKGVQLAQDHPPRNTRAFGRGELVRHLLASTASGAGADAA
                     HSFGDHASCEYIINWSNFKLRDTEPFFMADPFKTYVQDVRSHLSAR"
     gene            complement(56498..57418)
                     /locus_tag="PK063_04290"
     CDS             complement(56498..57418)
                     /locus_tag="PK063_04290"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96294.1"
                     /translation="MKTRRFNGRKILGLLLMAWCLQSVADWPPPAYGLEKYGRPLPSM
                     DEPEHEAREEEETLFGGYFLTGAFVKNPTFAARPDNTGLVGMRHMLHLETDLYKQYLT
                     FYTDQNFFSDRTDGWIKLSEWDGTFAFTGVLDRFNWRLQYERDAPLDRRGLKQAYADA
                     LVTARFQAIQDSTWWRRTFPHQNFTAYAGAGWLFHNSQYFARPNNTGRALFRYVAHAD
                     LDVYKNKVVLYGDVNLFTDREASQTLNPSELDWIVGIAVRWQDMELAFYREEDRPLDQ
                     SGLVQKYFAVQLRFAFDVSKGAMERVGWKR"
     gene            complement(57415..57855)
                     /locus_tag="PK063_04295"
     CDS             complement(57415..57855)
                     /locus_tag="PK063_04295"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96295.1"
                     /translation="MLPTGPGSLALSLIMQTAYVRLYIGLMNILLTGFVLGCQTSPPV
                     TEGYPHQQALQAKTLQEVLACAGNPLQKREDGPVTMLRYYREAPLLEESMVSSKGSRP
                     TVHHGCWATVILKDQRVDRVRYHFVPSSVDASNDCEEIFANCQE"
     gene            58475..61207
                     /locus_tag="PK063_04300"
     CDS             58475..61207
                     /locus_tag="PK063_04300"
                     /inference="COORDINATES: protein motif:HMM:NF014343.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HMZ96296.1"
                     /translation="MSSDSTARNVTQPLSALCGHEDSLNVPAVERKKTQDAWSLSLAE
                     RRASRRLALRLSTQLFFQGHTWKGVTRSLSLGGLSMDFVSDIPAMLNQRMMLSFSPDE
                     RGLDSVGIVCGIRSSEDVHVPGRTQAAVTLAIQFIHLSDADERVVASLLSHGATAPRH
                     MRLAAALVVQEGEESLIDTGSLQTAATPPASMQLVRGPERPREERRRQQRVVVGLSTE
                     VSLRTRGGDRPLSAGLTTDLSPNGACVHLSAEEDLLGSELELRWLPSAPLQGSSTDSL
                     SATLCSVVGEVVWTRPVAPEARPGCVPVAGRTVLAGVRFLPVAKEAEDIIEHFLGQVS
                     MPSPETKVGSPTVLSEFSECFRPSGLRIVICHDRPQVAPAADAPIIVLAPGYGESKRD
                     YVPLAYYLAGNGFHVVRYDNVNHVGESDGLVTQFRLEDMEADLETVLDHVANQWPGRP
                     IGLVATSLAGRVALKVAGKVSHVRLLTLINGIMDVRHTLQAVHQEDLIGEHLSGVHKG
                     VVNIMGLTIDADRWLAHAVEGEYADLLTTQRDASRLQTPVVLFHAEQDAWVDPASIER
                     VTEAIGPYLRHSFVVPGALHRLQESPRKARTVYRQIAVCCQQELWPARRPERMVEPSH
                     REIGAQNRLERERSKKRKPMGKSDHVAFWQEYLQNFQTIPNVADFWRLMDHLYRLMGD
                     CHKGERILDAGCGNGNFGVFLQLNQAFRQRYGKRGDFRSPDYVGLDFVPAALAQAMSN
                     FEQVGATLQGQFYEGLRAYEPMSMRVCQADLESALPFPDHSFDRVVCNLVLGYVRDPL
                     FTLREYLRVLTPQGRLVISNLKPYADLSAIYRNFVDTAQTKDQVEEGRRLLDNSGRIK
                     EREGEGTFHFHYQTELESLLRAAGVSRPRVYSTFGNQALIAVAEKGMAHVTVAA"
     gene            61241..64249
                     /locus_tag="PK063_04305"
     CDS             61241..64249
                     /locus_tag="PK063_04305"
                     /inference="COORDINATES: protein motif:HMM:NF028237.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ96297.1"
                     /translation="MKVLAISALVNALAATGLGMFVYFRDPAAARNRIYGLYCLSIAF
                     WSVFYCGWQLAESKDLALSLLRLVMAGASLIPILYFHHTVTFLDIAVRHAKALKIGYG
                     LAGLFLLVDTTPWLVAGVHPAMSFSFWPVPGPFFHPFLAYFLWYVVYATSLVGVALRD
                     ANGIRRHQYAYMLAASVIGYAGGATNFPLWYGVPLLPYGTVLITMYTALMAYTIVRYR
                     LMNISVVLNKGLGYAIVLAIIVVATSIGAVLSNRATGHSTPPLLAGTLFLICALWVLS
                     NNPRSSSNTVFSAVCGAACLWLFGCFMLFSATHEEEALFWVRVIYTGVVFLPALTYHF
                     AQRLAGGAVPDRAIGWNYALGGLFWSLLFTTYVVDGQYVYYWGRYPKAGVLHPWLVAY
                     VVGGGGLTVYRLYQGYRFHQTSAPLLGAQLKYTFVALLLGFSASLDFLQNYGIGFYPV
                     GYLLAGLSVTVVAYAIARYELMDISFVPSRPKVMLSIKLAGLIPAYMMILLVIRIFTG
                     TFHYLLAGVLFGLFVIVSSGLANLQKGVERAIGQTLFRERYDAYDTLVQFSKSLVAIL
                     ELKSLTKEIVQTLARVMNIKTASVYVLDKEQGVYSLTASYGFVTRDVIVPPIKMESEF
                     PRALLRTETALVREEIEYDKADVDYLRLLDTLKGLESEVCIPLVSKERLVGFCNLGRR
                     ANHGMYSTEELALLKTLAQHAAIAIDNALLYEDLRRSQLLMRRTDRLRSLETMAGGFA
                     HEIRNPLTSIKTFVQLAPDRRDDVEFMEQFSQVVCEDVERIERLVHEILDYARYMTPK
                     LTQESLNDVVSSCLYFIEVKASSKAITIQKELAPDLPYVKLDRQQIKQVLLNLFINAM
                     EAIGGEQGGRLSVRTRKLVKSVNEPWVQIEVEDSGPGIEPHDLDHIFDPFYTTKHESG
                     EREGTGLGLTIAHQIVQEHGGYVEVFSEVGHGTKFMVSLPVNPPMAEWQAAQPVYDDG
                     RKLAGSFLARPHLGLEQQFSKPDSPLKTRT"
     gene            complement(64351..65334)
                     /locus_tag="PK063_04310"
     CDS             complement(64351..65334)
                     /locus_tag="PK063_04310"
                     /inference="COORDINATES: protein motif:HMM:NF012770.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HMZ96298.1"
                     /translation="MTILNGFTPALLLRNPHLMTLIPRYWPRLRWKENLPCCERLFTT
                     QPGTQLLGFCHWQDDPTTAPTVLLVHGLEGSADSHYMRGMAAKAFCAGFNIIRMNQRT
                     CGGTDHLTPTLYNSGLSNDYLAIIRELRERDGLSHIWLVGYSMGGNLVLKAAGELQRS
                     EAALAGVVAVSPNIDPTQCVAALEEPRNWLYHAHFLSSLKARMQRKAALFPGQWNLSP
                     LRLMKTITQFDDTYTARDGGYRDATDYYNRAGARHVLSEIAVPTLIITAQDDPFIPAS
                     MFDSPGIKNNRYITLAMLRNGGHCGFFQKRRYGEDRFWAENRIIEWLSSRA"
     gene            65476..66105
                     /locus_tag="PK063_04315"
     CDS             65476..66105
                     /locus_tag="PK063_04315"
                     /inference="COORDINATES: protein motif:HMM:NF012804.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HMZ96299.1"
                     /translation="MLTAIGDVMRRVYERGWITTRDGNISMRKRDGKYLYITPSGWRK
                     TIVHPEHVVRLEVVTDPTSGHLVPSVREGQQPSGELWMHWNLQRDTKKTRTVVHVHAT
                     HIVAAMYAGIDLQAMSAEFPEISRYTRVGRTVPALPALSRDLADVTAECLGLRKDGTL
                     EFDIVGQKNHGVCAVATDPWAAYEHIERLDHICEIVLKSGVAARSSGKL"
     gene            complement(66302..66841)
                     /locus_tag="PK063_04320"
     CDS             complement(66302..66841)
                     /locus_tag="PK063_04320"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96300.1"
                     /translation="MDWAAFFQVIKMKVFPLYIVAILFLTGCVTAEMILGQRPVTKVK
                     MGSTVDYPGRPFIDASDEIFSLSQQLDPIMRSGNFELKERIQSYGLLPHTGTTYTSDY
                     RLQDKRFEGWVRCLITIDSKDITVSFMTVESQHGKRDYPPAEEVRSLAANITPKLRSY
                     LQSRFPERALEVSELYWQM"
     gene            complement(67425..>67738)
                     /locus_tag="PK063_04325"
     CDS             complement(67425..>67738)
                     /locus_tag="PK063_04325"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96301.1"
                     /translation="PGHRSRNRLSRYVISQYVQDQSGYVNMCWSWKRSLGFPMSTLWE
                     EMRNQWSSRNAFRRIRGEIEIPRVVLFKTWEDLLAGHAIWFDGFILQLVLGKGLTFSK
                     P"
BASE COUNT        13705 a        18718 c        20567 g        14748 t
ORIGIN      
        1 gagcagcggt ttcgtaaacc gcaggtcggt ggttcgattc cactcgccgg ctccatttat
       61 caagcactta cattgccaca agcttcgtga tgcgaatagg tgtatatttg catcatactg
      121 tgaggcgaat gtgtatatct gggaattgcc tgactggcca cgctttcgct ggcaagctga
      181 caagttactg aatccactag gggatgccca cctgaagcaa ggtcggcttc ttggcaaaat
      241 gatgcaattg ggcttcgagg tacgccttga agctgaactg ctggctgtga cggatgaggc
      301 cgtcaagagt gcagaaatag agggcgaaca tttggacccg tcgagtgtcc gctcatcggt
      361 ggcacgccgt cttggcgttc gtggggccgc cctcggtcag gaagatcgac gcattgaggg
      421 catggttgcc atgatgctcg atgctacggg ccaactggat accccgctca cacgtgagcg
      481 attgtacggg tggcaggcct cgctgtttcc gactgggtat tcaggtttac gcaaggtcaa
      541 gaccggcggg tggcgggatg atgccgatgg cccgatgcaa gtactctcag gtccggtcgg
      601 acgtgagaag gttcactttc aagcgcctcc ggctgaacgc gtcgatgccg aaatggacgc
      661 gttgctctca tggctgaatg cccccctcac catcgacggc atcctccatg cgacgatcgc
      721 acacctgtgg tttgccacca tccatccgtt cgccgatggg aacgggagga ttgcgcgcgc
      781 acttgcggag cggagccttg cacgctccga acagtcgcca cagcgattct atagtctggc
      841 gggccaaatt caccgcgaac gccccgagta ttacgcctcg ctcgaagtga ctcagaaagg
      901 cgacctcgac atcacgcagc ggatgctctg gtttattgaa tgcgtgtccc atgcgatcga
      961 tgccgccgag gcgggatgcg cggatgtgtt gcgcaaggcc gcgttctggc aacgccacac
     1021 cggtctcgct ctgaatgcac gccagcggaa agtgctgaat cgattgctcg acggatttga
     1081 gggcaagctg acggcgagaa aatgggcggc tctcacaaaa tgttctctgc caactgctca
     1141 acgtgatatc aaggagctga tggatcaagg ggtgctgatc cgtaatgagg ggggcagtaa
     1201 gaacacaagt tatagcctca cgggacctcc agaataaggc cgacgaggtg gatctcacgc
     1261 tgattgagaa agtgccagaa caacgcaagc gtgtacgtgt gtggaaaacg aaatggcgtg
     1321 gctatggact gaccccctag cttgagacag ccaacattgg catcatcgga caagagtgcc
     1381 tgcgctcctg taaagctgac catcctccct tcagggctgc ggtaaatcct cgtcgaaggt
     1441 tgctgccgtc caactcggta ccggcttcgc tgcagaacac aacccgggtt tcaattcccc
     1501 gtagcccacg accctgctcg tatttatgag agagcagatc cactacggtt tggttgagcg
     1561 gaatcgtccg ccgttccccg ttcttggatt taaacaccgt gacggttcgc cgtgtgaagt
     1621 ctactcctgg ggaagtgtga ttttgagggc cgaagggaat tggtgttgtt gagaagaaaa
     1681 gccctgaggt gacgatcctc aaaaacgtcg ctgacaagct tcgtggaatc agtgatcggg
     1741 tacgaacgat tgcgcacgag ctccgggtga tcgcctcagt ctttgcgagt tcctgtgcca
     1801 tctcctccag ggcatgatcc gcaagatcat cctcattcta gatggccatc ctgcgcgaac
     1861 agtcaagcgg gttcagcggt ttgttgccgc gcaggccggt ctgctagagc tgcgcgtggt
     1921 gccactatcc gtccgacctg aacttcgatg agttgacctg ggtgcacgtc actggaaaac
     1981 tgggccgcgg cgcggacaag gactgatttg aaagcccgcg tccatataaa tgccagttga
     2041 tatttttaga tggaagtccc aaaatggcgc cgcttcacaa ccaagcaatt atactcatgg
     2101 tgagaagaga caaagaaaag cgagatgcgt agataaaaat atctggcaca gccttgctca
     2161 aatcgctcat ggatgagttt gtggtgaaca atttcgagac attcaattcc gtgaacacgc
     2221 tggtggatcg tgcggtgcgg tatgtggtga aacgctatga cgcggcagac ggtcgaattg
     2281 ataaggatgg gttcccgctc gacgtagccc agaggatcgg ctcttctacg aacgtgcgcc
     2341 ccaagccgag gagaagaagc gccatagccc cccttgagcg cgcggcatcg gtctaggcat
     2401 tgaacgcaac gctaccaaag cgacctgccc agactggtac gggaatggct ggcagacgac
     2461 atgaacgtga agtggttcac cgccgaaact ttaaaagcgt tctcccgagc gtgcgagttg
     2521 tgcagtactg ttggcggcac gcagtgtcga ttttgcatga ggctgattgc cgagcgtgcc
     2581 gagtgatacg tcggccatgc aggaggcaac cgccccatcg gtcagctggc cgactacgcc
     2641 ggacgggggg atcagagacc aagcgtgtct tgagcataac ggctggaggc tggtcgagaa
     2701 atgagacgct atgtcggcat atattccgag catcagcact gatctgttta ttttccaatt
     2761 atgtagcgct cacgttatca ccgtcgtcga cgatccgtgc gcctgaggcg cgtgcctgtt
     2821 cattttgtcg agcgacgaac ccagctccat acctcacacc gtagtcttgg aggacatcac
     2881 atgcgcacac tacccaggct agcggccggt ctttccgcac tactcctcac cggctgcgta
     2941 gacctctcct ttcgcatcac gccggagaat ctttcggtga aaccgatggc ggagggcaag
     3001 acctgcatat acaccctgtt taattttggc tacggcacca ataccgtcga gcaggccatg
     3061 gccaacgcca ccccgccgat tcagaacatt cgcagtatca gtgtaacgat gtttcatttc
     3121 ctagtcttcg aatcacactg cctgaaggtc gtcggtgaga gcgctccggc cggcgaggga
     3181 gcacgctaat tggaacatga tgtgttcgca agaggaggac cccgcatgcg cacgttctgt
     3241 acgctgaccg tctgtctcgc cgtgcttctg ctcactggct gcgtcagcat caccaatcgc
     3301 gtcaccccag aggatctctc ggtgaaaccg atggcggaag gcaagacctg catgtacacc
     3361 ctgtttgagt tgggctacgg caccaatacc gtcgagcagg ccatggccaa cgccacgccg
     3421 ccgattcaaa aaatccgaag cgtgagcaca agtctcttct tcttgctgtt tgtgaataag
     3481 agctgcctca tcgtggtcgg cgagggcgca ccagcctccg caccatagcg gcgacgccaa
     3541 cggagacggt ctgtcgacga ttaccgagta ctggagggac tatacgatgc atcgactgat
     3601 ctgctgcacc tgctggctga cggccctact cctctccggc tgcataaatc tctcaattcg
     3661 cctgaccccg gaggatctct cggtgaaacc gatggcggag ggcaaggact gcgcgtatgc
     3721 cgtgtttggg tttggctacg gcaccacgac cgttgagcag gccatggcca acgccacccc
     3781 gccgattcag aacgtccgaa gtgtgggcgt aaacgaattc tacttgctag gtgtagccag
     3841 gctctgcctg atcgtggtcg gcgaaggtgc cccgggcacc accaaataag cgcaccgtga
     3901 ccccgcgacg actggggtga accccttcac tgagacgggt tggcattagc acacgttgga
     3961 gtgattgccg tccttcctct acgagacttc tcccggtgtt gattcctgtg caggcctaaa
     4021 aaacggaatg cgcgcggcac caggcggcgg tccggacgcg aggccacgct caaaatcatc
     4081 tgggggccct ggtgcaagtg tgcccatgtt ggctgtctca aactagggga tcagtccacg
     4141 cggtagtact taatttgtgc taatcgatcg caacacctct aagccgtcca ctccaatcag
     4201 aacctttccc ggcaaatttt ccgccaactg acggcgtaac gcggtgccat cgccgtcaac
     4261 tactgcctca gctatcggac atctttctct agttcgtctc cgaccttgac cgctcgcgat
     4321 acgcatgtat gcgaaggatt aaggaagtgt ggttcccgca gcaccctgtc acgccttctg
     4381 aacttggcgc gtatagatat tctcagcttg aggaaggcat ggttcgattg ccttaatccg
     4441 tctgcgaaac ttggcaccag ggctttgtcc agtagcctcc tccagagacc agcgtaggat
     4501 gaaagcgagt gaagcaaggg tgcctgaccc tctagcggag gaaacaacat gcgactccga
     4561 tacacacttg gtttcttgtt cggcgttcta ctgttgtcgg cctcctgcga ccagggatcc
     4621 aagccggccg acaagtccac gccgccctcg aatgcggcgc ctacatcatc caatttaaaa
     4681 gaaacgcatc cggaccagcc gaccggactg ccgcaaagtg gcgaagggaa gcaagtcccg
     4741 acaaagcgcc gtgaagcctg aaggggtgat catacacggg ttcttacctc taggaggacg
     4801 atatggctcc tacaaaatgt gcccatccat cctgctcgtg caaagtcgaa ggtaaaaagt
     4861 attgcagtga tcgctgtcaa actgctgcga ccaaacctga ggctgccgct tcctgccctt
     4921 gtcatcactc cggatgccaa gcacatcatt aaaggcaggt gtttctgatc ggcgtggaaa
     4981 gaagcaaatg agggagtgct catgcgcacc atccgctgtc gcgaacgatt gggcgagcag
     5041 gagtgtcacc gcgagactgt tcccgaacgc gagcgggcca tagcgataca ggctgggatg
     5101 tcgggtctcc gttatgagtg cacccagggt caccgatttc acctgagtgc ggacgggaga
     5161 gtgtcgaggt gcgattgtgg tctcgaccca gtgcgcaggg aatgagacgg cgtgatgggg
     5221 gggcgtacgg cagatcctcg atgttgcccc tgggttcatg gggatgatta tctccgcaca
     5281 aacagagatg tgaggcacct atggaacgaa aacgtaagaa ggtcgtcacc gacgctgacc
     5341 agcagatccg caattattat gagcatcagc cgccgtccga aacggaagca tttcctgatc
     5401 tgtccgaaac gatcccgacg tctgagcaat tgatgggaaa ggtggggcat atggaacagg
     5461 atcgttccgg actgaacggc gcagatcccg atgtgtcacc gcaaggcatc gacgccggga
     5521 cggaaacgcc gggaggttct gaaccgacgc ctgaccaaga ccttgtggac gaaatcggca
     5581 aggccgctgg ggtgacgtat caagatgacg agccgctgaa cttcgacgag aagattgcgg
     5641 ctcatgatga agcgcgttgg gaactgaatc ccgcctcttc ggaagatttt gaggagcggc
     5701 aatcggaact gcgcggaaag atgccctctc gtcgcatacg aaacggcgag gaaaattcct
     5761 gaacaggaga gagctggtag gacaatgctt tcgccttcgc gagaaccaaa aacgaggtcc
     5821 tagggaagtc cctagttata accaacgagg taaaatgcct aaatgacgtc atgaggagtc
     5881 gagatgatct ttctcggtcg tcgcatgaca gtgcgatggt cgggcgaggg aaaggaacaa
     5941 gctatggccc tcatcgaaaa atccatcgag gtcaatgtcc cggttcgaac gacatacaat
     6001 caatggacgc agtttgagga attcccgaag tttatggaag gggtcacgca ggttcaacaa
     6061 gttgatagca cgcatctgca ctggaaggca cagattgccg gcaaagagaa agaatggaat
     6121 gcggtcatta cggagcaacg tccagacgca cggatcgcct ggaaaagtac ggacggcgcg
     6181 aaaaatgccg gcgtcgtgac gttccaccgc ctgtctgatc agaaaagcaa ggttatgctg
     6241 cagatggact atgagccgga aggggtcgtc gagaacatcg gtgaggttat cggggccgtg
     6301 tcgctccgcg tcgaaggaga tttaagtcgc tttaaggaat tcattgaaag gcgggggcac
     6361 gaaagcggcg cctggagagg tgaggtcaag gggaagtaat gcccgggcat tgcgcaagtg
     6421 gatcagacca tacatgtaat gggaagacgc tgctacaagt attcttgtgc tcctacctaa
     6481 gacgcgcttc ctgactgccg gttttccggc tcaggatccg cagatgcaag ctcactccgt
     6541 gctgttctca ggcctagatt accggcgatt tcgcgagtcc ggtggaggca atctattggc
     6601 cgaggtgtct ggtgcctttg cgacagaatg gcttgcacaa caactgatgg ctgccacagg
     6661 gagcgagagt ggttcaaaca ggcaatgccc gaagcgatcg tgtcgtggga cagtctcctc
     6721 gctcatatcc agggaggtat ggtcctcgga atgaggaggc gttcccgcta ctcagagtaa
     6781 tgaccgcgtt cactgtattg ttgctgctct ttctcattcg tcccgtccat gctgcagact
     6841 attacctgac cgctacaggc gatgatcgcg acaccggtct ctcttccgac catgcctgga
     6901 gaacgctgga tcgcgtcaac cagcttgagc tcctagcagg agatcgcatc ctcctcgaag
     6961 cgggaactac gttcctcggc cctttgctgt tggatggggc agatcgggga acagaatctg
     7021 ctccgatcac cgtcacaaca tttggtaatg ggcctgccgt catcgaggct ggcgaaggca
     7081 tgggcatctt tgtacggagc actgcggggg tcattctctc gaacctgcat gtgtcgggaa
     7141 atcaccatcc tcataacaat tcagatggca tcgcgattca taacgatctt gatggagccc
     7201 tcctgctgac cggcatcacc atcgaccatg tggaggtgag tggatttggc aagaatggaa
     7261 tctcaatagg cggatggaac ggcgacagcg gctttcggaa tgtacgggtc acgcacacac
     7321 gcattcacga caatggcctc aatggcctgg ttacctatgc gcaacatcct cgtgccaata
     7381 aagacgtcta catcgcctat gtcgaggcct atcgaaacac ggggttgcca ggcgtcgtcc
     7441 ctcacagtgg cagcggaatc attctcggca atgtggagaa tggggtgatc gagtggtcaa
     7501 aggcctacga gaacgggcgg ttggggaatg ccggtgtcgg aatctggacg tacgattcga
     7561 cgaaagtcgt gatccaacac aatgaatcgt ttgcgaaccg tacctccggc gaggcggatg
     7621 gcggcggatt cgatttggat gggggagtga ctgactccgt gatgcagcat aacttttctc
     7681 acgataatga tggtgcaggc tatggactgt atgaatatgc cgaggctcct ccctggtatg
     7741 gcaataccgt acggcacaac ctcagcgtca atgatggtcg caagaacggt gctgccggca
     7801 ttcagatttg gaatggcggg acaagtctct tagccgatgc gaccattcac gacaatattg
     7861 tgatgatggg gccatccgaa gatgtcacgc cgagcgcaat cgcgtttaag tctcccagtc
     7921 agggattctc gatctatcag aatgcgttta tcgcgagtgg tgaagcgatt ctggtgttca
     7981 aaccggcgga gcaagtccat ctccacatgt cggataaccg gtgctggtcg atgaccacgc
     8041 gatccttgtg ggacgagtct ctcgaaagag aggtgtgtgc catttacttt cgtttccctg
     8101 gatgaaggtg tttaccagga ttgcggtcac tgcacggtta gacgtcttcc attccggagt
     8161 gtgtgagtga ctcgtgcgtt actcctacca tcctcaaccg agagggcagg catgttcgca
     8221 cgagtctgcc gattgtttcc gttcagatca caacggcgtg acaagtcacc gtcttgtgcc
     8281 gagacgtata gaagaaagtg aagcgtaatc gaccgtggac agtcccatca aagttctcga
     8341 tgtcgatctt gcccatccac tccaggacct gggcggcctc gatccctaca ggtcggtgtg
     8401 gggacttcta cgattgaacg gtcgaccggt cggagacgtc actgtgccta ttcgagatgg
     8461 agtttgcact gccgaatcaa tgtacgaagc catcgtgctt caacagggac ggcctattct
     8521 ccaagcgctt atcgcccatc acctgcatga ccccgtgtcg cgcgcgggca ttcgcaccct
     8581 tgacccgatc gggatggatg acatgcccgc gaatgtctgg ccgctcgtca cagtcgcggt
     8641 gtgtacgcgg gatcgttctg agggattgca tacctgcctg catgctcttc agaagctgga
     8701 ctatccctca cttgaccggg tcgtgatcga taatgcccca caaagcgaca gaaccgagcg
     8761 cctggtgcgc gaggaatttc cagcagtgcg gtacgttcga gagccgaggc cgggtctcga
     8821 ttgggcaaga aatcgggcgc tggcggtggc acgtggcgac atcgtggcgt tcacggatga
     8881 cgatgtcatt gtcgaccagc gatgggtgcg caccctcgcg gaagtgtttg tccgtcatcc
     8941 ggaggtgatg gcggtaaccg ggttagtggt gcccgctgaa ttggaaaccc gggcgcaaat
     9001 actgtttgag acgtatgggg gattcggccg cgggttcgag caacggtggt atcgagccca
     9061 ttctacaaag ccgcaggtcg atacgtttca tcttggcgct ggtgtcttcg ggaccggcgc
     9121 caacatggcg tatcgtcgtg ccctgttcaa aaatctgaac gggttcgatc cagctctcga
     9181 tgtggggacg gtcaccaatg gtggcggtga tctcgagatg ttttttcgcg tgctacagga
     9241 gggctacgtc ctcgtctatg aacctcgagc cctcgtccgc caccggcata ggcgaacgta
     9301 tcaagaatta gcgacgcagc tcaccaatca cggcgtgggg ttgtactcct gtttgtcccg
     9361 atgcgttcgt gcctatcccg ccctccgtcc cgcgggggtg tgttttggcg cgagatggtt
     9421 ctggtcatgg aatattcgcc gactcctcgt gagctacgtg cgccgttcgt cattgcctcg
     9481 cgacttgatg gtggccgaac tgcgcggatc gctccgcggt ctctttgcat atcagacggc
     9541 tcgacgcaca gcgcgtaggc tgcgcgatct gcaggcaggt acaggtgaac gcgccgaaga
     9601 ggacatgttc ctcaagctct cgtcagacct ctcgcattcg ccgactgggc agccgggcaa
     9661 agcgtcttgc agtctgctgc cgaagccgca atttcccatc gccgtacgtg ccgtggaact
     9721 cagtgagcca ttgagcgata tcggtgatct ggagaaatac aaagcgctgc agctgtacgt
     9781 gaccctgcac ggtgagctcc tcgggaaaca caccattgag catactgcgg ggatcgtgcc
     9841 ggtcgctcaa ctccgccaag ccatcgccaa atcgtttggc atacgcctgc tctcacgaga
     9901 cacacaccat ctcggcgacg caccctggaa cagaatcatc gcagacctgg ttgagcggag
     9961 tccgattccg aatccgcagc ctcccaaact gtcagccggc agccgggttt ccattgtgat
    10021 cgccacgctc gaccgtccgg aagagcttcg acactgtctc ggcgcactgt cacgccagga
    10081 gtcttcacgg caagtcgaaa ttattgtggt cgacaataac ccggcgtccg gtctcacgca
    10141 gacgattctg aaggagtttc ccgcggtggt ttcggtgcag caggctcgca ggggactcag
    10201 ttacgcgaga aattcgggca ttgtgaaaag ctccggcgag atcatcatca tgattgatga
    10261 cgatgtcacg gtgtcttcga cgtggctgga acggttgatc ggccattttt ctcggccaga
    10321 cgtcatggcg gtgaccggca atgtgcttcc tctggaactc gacacggagc cgcaggtgtt
    10381 gtttgagacc tatggaggat tggggcgagg gtttgaacgg ttggatgtga acggaagctg
    10441 gctgcgtgcg ttttactcgg ctccgagaac ctgggtgttg ggtgcaacgg ccaatgccgc
    10501 atttcgagcc agcgtctttc gtgacgagca catcgggttg ctggacgaag cgctcggcgc
    10561 cgggatggct ggagtcggag aagacacgta cctgttttac cgcatacttc gagccaacca
    10621 cagattggtg tatgaaccat cggcctatgt ctggcacaag caccgacgag acatccgtgc
    10681 ctttcgtcgt caactgtttg cctacagcaa agggcatgtg gcctaccatc tcacgacgct
    10741 gttccgggat ggggatttgc gcgtcctgct ctatctcttc gtgtcgcttc cccgggccta
    10801 tctgttcagg gcgaagtcca gactcctggg gcgaactgtg tatccgttgt ctttgctgct
    10861 gctcgaaatc ctcggcaatc tgatcggtcc ctggacatac gtcgcgtgca ggtggaaagc
    10921 cagccggcac tcagccgaga gggtctcacg atgaccgctc acaacatccc ggcggtcgat
    10981 agcctgcctc accgcgagga gccttccacg gaccagatat ctgccgattt ccgcatgctc
    11041 ctcggggcgg ttgatgtggt gtcgtttgat ctgttcgaca cgctcattca acgggatgcc
    11101 ctgttctgtc ccaaagatct cttctatcgg gttcaggccg tcgtcgaaca tcgccatgcc
    11161 atcacactca aagatttcgt ttctacccga gtacgggcgg agagtatcgc ccgtgttcga
    11221 gcgcgaggac ggcagagtga ggaaacgacg ctcgaagaca tctacgtcga aatggccaat
    11281 atcctgagtc tgcccagcag tttcgctgag gagatgctgc acatagaact tgagtgcgaa
    11341 cgggcagccc tgatggcctt gccggatgga aagcggctct acgacgccgc aatccgcgca
    11401 ggcaaaacca ccgtggtgat atcggacacc tatttgagcc gggtgtttct cgaagagatc
    11461 ctcatgaagg ctggattcaa cggggtgcat cgcgtgtatg cctcctcgga attcggaaag
    11521 accaagcacc acggcgcgct cttcggcatc gtgctgaaag atttgaagtg ttcgccgggc
    11581 cggctgcttc acgtcggcga taaccccctg tccgacgcca ctgccgcgct gggtcaagga
    11641 ctccgaagct tcatctgcac caacccgaaa caacggctga agtggcgcta tgggctcagc
    11701 gacagaccca gcgggagtca ggccatttcg gcgctgttgt gcgacatcag ccgaactgca
    11761 gaggagcaat ctcacggcac gaccgaccgt gccgtgattg ctcggagtgc cgtggagcat
    11821 ctctcctggg tgtatgaggg gttcgccgcc tggttagtgc atcagatggc gagtcagagg
    11881 gatacacgag tctacttcgc ctctcgtgac ggccttatta tgaaaaagtt cttcgacgtc
    11941 acgcgaaagg ccttcgggac cccgattgag agtcgctacc tctatgtctc acgggcagcg
    12001 ctctatccga tgctggttct caccgatccc gacatggcgc gacggttgtt ctgccatagc
    12061 tgggaccacc tgacgatgac acaggcctta aagcggatgt ccttggttcc tcaggaagtt
    12121 gccgggcaac tggccaaata tggcctggcg gatcctctgc tctcgttgaa tcgagtcacc
    12181 acattgaagc tgagccggtt cctcgatgcc atctggccgt tactctgcgc aaaaagtgag
    12241 agtcattgcg aactcgtggc ggagtacctt cgacaggagg gattcttggc cgacgagcct
    12301 acggcatttg tcgatatcgg atggcacgcg tcgctacagc actgccttgt gaagctgctg
    12361 cagcatcgcg gtttcaagaa tactcttcac ggctattatc tggggacctt tgccaggccg
    12421 gacgcatccc cggaggtctc tgcgaaaggc ttcttgatcg agaatgatgc gcccgcatcg
    12481 atctccgccc tgatccggac cggtccttcc ctgttggaac tattccatgc cgccggccat
    12541 ggatccgtgc tgggatacga gcgtaaagac ggtcgcgtcg tacccgtcct ggaagagaac
    12601 gagcgcgagc aggaacaatt ccgcaggatc atcgaaccgt tacaacagca cgcctttgag
    12661 tttgtcgcgg cgcgcctcgc ccgaggagat aagccggagg cctcgacgtt tccgcctgaa
    12721 ctggtcgccc gcttggggtt acgcatcctc cacaagccaa ccgatgagga agctgaaatt
    12781 ttcggacgac tgagaatcgc caccgatttt ggcggcagca tgaagagtct cacgggcgct
    12841 tgcgaatgga acctctcgga ggtggtggga gatgcgcttc ctgacggcat ccctcccatg
    12901 tggtatccgg gattttatgc gctaaaaaaa tcggccacta agcgagcctc gtagggacca
    12961 ttgtgatgga cgaccttcgc gatactcgca ttgacacatt ggcgctcagg gaaaaatacc
    13021 gcgatcaata ctttctgcat cgcgatccca tttatcaaga ccgtttgtta tggcgagcgc
    13081 atacgttccg gcacatcatg catctcctgc ccactcaatc aattttggaa ctgggctgtg
    13141 ggcgcggatt gttcacgccc catctctgtc gtgtgtcgag gggagagaat cccgtcacgt
    13201 ccgtcacgtt ccgggctcaa caggctcgcc ccgattctct ctctgccgac gttgagtttc
    13261 tttacatctc cgcgcttccc ggtccgctac gggggaaaca ctatgatttc atcgtggcca
    13321 tagatttact ggatcaacgt aactgtggat ggttcttgca gcagatctat gagttgttgc
    13381 ggccgggtgg ccaagtcctt ttttatgaaa gcaacccttg gaacctggcg ttgcgagcaa
    13441 aacactgctg gcgccgcctg cgcggcggcg acgatccgcg tcgcctgttg aatcgcccgg
    13501 ttctctacga attgatgtcc gaagtcggat tcattcgcgt attcgccctg tacaacgatt
    13561 tcgtatatgc cccgttaacc cgttcgctga tctggtttct acgcaacatg tcgattctcc
    13621 ttgagaacgc caggggcatc caaacctttg ccggctctat cctcctgcac gcccagaagc
    13681 cgccacgcac taccgtcaga ccgctgcgtt ccctgtgcga acatgcgcaa ctccatcgtg
    13741 cgatctcggt cgtcatccct tgccataacg aggagatgaa tgttgagccg ctggttacgc
    13801 aactgatggc gctctacggg gactatatcc atgaaattat tccggttgat gataacagca
    13861 cggatcgtac tgccgaggta ctgcgccgcc tggccggcgc cgagccacgc gtcaaaccgg
    13921 tttttcggac tccgccgaac ggggtgggac gagcgctggc cgacggctac cgagtagcga
    13981 cagggcagta cgtcctgtct atggactgcg attttcaaca tctcctgcct gagatcaggg
    14041 atctgttcga tgcggcagca caggggtacg acgtggtgat cggcagtcgt ttttcgcgcc
    14101 atagcgtgtt gctcaactac ccgttcaaaa aaatcctggc taatcgagcg tttcatgccc
    14161 ttgggcaaat cctgttttta cgtcagttcc gggatctgac caacaatttg aaattgatgc
    14221 ggcgggaggt ggtcgagcgc cttcaattaa cacagccgca ttttgccgtg aatgccgaaa
    14281 ccggtctgca accgttgctg atgggctatt cactccggga ggtgccgatc tcatggatca
    14341 accggacacc cgatatgggg agctcttcct ttcatcttgg caaggtaggc cggggctaca
    14401 tggcggtctt gttccggttg tggtggaaac atcttgcagg agcgatcgcg gtccctctca
    14461 agatgaaatc gtcaaactct gaatcgagct tgagatagcg gccatggcgg tcacgcatga
    14521 cgaaccggca agcatgctga agcaggagga tttcgtcttc acgaattcgt cactcagcca
    14581 agagcctgcc aatactccag tctggcgatc ggacaggtcc gtgcgggtgt tcgtgttgag
    14641 catctggctg gggatggtga tgctcgcgat ggtcaattgg gccgaaggca gtcgaaacgt
    14701 gccgtttagt gaggattggt tactggtctc ggcgctcatg ggccatgaac cgtatctcgg
    14761 cacatggctg tggtcacaac ataacgaaca tcgtgttccc gtgccgcggc tcattctcct
    14821 cgcgctcctg acagtgggac agggtgattt tcggatagga ggagccttta acattctcgc
    14881 cctcggcgga gtgtcgctgt tgatgatgga aacggcgaga tccgttcgcg gtggctcgtc
    14941 gcgagtcgcg gacgcgttct tccccgtggc gttccttcat cttgggcata cagagaatat
    15001 gctgtggacc tggcaaatca cgcaggttct tcccgtcatc ttggtgtccg ccctcatgct
    15061 catcgtggtc gccgggcgga ttcctcggac caccgcatca acacttgccg ccggtgtctg
    15121 caccatcatg ttgccgctct gcggggcaaa cgggttgctg tatgcgccgc tgtttgcctt
    15181 ctggatcggt tacgtgggga tcgtgatcat agccggtcgc tcgaatgaac acatcgccgg
    15241 ggaaaactgg aaaggtcggt acttggtcgg cgccgctgct gtgacgctac tcctgtccgg
    15301 actctatttc gtgcagtatc acccgccaca gtatggcgcc gaagcgccga ccctgccggg
    15361 cgcgctctac gcaacgctgc aatttatcgc cttaagtgtc ggacccgccg caagaatgtc
    15421 ctgggtactc tcgattgctg cggtgatggt gtgtcttgtg cctgcccttg tcattggcgc
    15481 gaggcacttc gtcgcacggc aggacaggaa cccatttcgg cctgtgggag tggtcgtctg
    15541 cgcggccaat ctcctgctgt ccgccttggc tattggctgg ggccgcgcgc aagttctttc
    15601 attgtgggga gggctctggc ccatccgcta ttccctgttc gccgttccca ttctgtgttt
    15661 ggcgtacttt gtctacgagc tctatggatc cacttggacg cgtcaggcgt ttcaaacgtt
    15721 gttattcgtc ggcatggtcc ttctcgtacc ggcgaatgcg acgcaaggtg cacgatggca
    15781 cgactggtat ctgcagggtg ccggggcatt cgagcgagat gtgcaatcgg gtgcatcggt
    15841 tagccgggta ggcgaaagga atcgtgaata cttatatcga tggatggacc ccagtttcga
    15901 caaagtgagg atgcttcgag acagtgggat cgggccattt gcgaaaatgg ccgaggagcc
    15961 gtctgctcca gtccaagcgc ctcgtcacca gggaatgccc gagtctcccg tagcagagtc
    16021 tctgcctgcg gcgaggagag agttgcgctt tgttatgccc gaagcggccg aggtgtttct
    16081 cgtgtggggc atcaacggct ggcaagccgc ccctgaatcg tttcgtcccg ccggaaccgt
    16141 ggtgaaagac cacgtgttgc acacgcccat gcatcgacaa gacggagtct ttgttatgcc
    16201 gctggccctt cctcgaggcg cgtcgctcga ctattgcttc ctcatcacga agaagcggga
    16261 ggcgttcgat attacctggc ctctgtgtga agggaattac catgaggagt tcatggcaga
    16321 cggagtgagg gagatccgtt cacgcacgag ccttgcgctg gtgagacagg aaattcgcta
    16381 ccacgcgccg gaggccaaag aagtgcatct ggtgtggggc gtgaaagggt ggcatgtcac
    16441 tccccaatca ctctggcctt ccggcacggc cattatcgat cacgtcatgc acacacctat
    16501 ggctctacga gaggggatat tcgtcgccac cgtgactgtt ccggtcgata ccgcggtcga
    16561 ttacgggttt cagattacaa aacgtcgagg catttttgat ttggtgtacc ccctgttcga
    16621 tggaaattac agcgtgcgcc cgagtcaaga cggacagatc gacatgcagg caaagcccgg
    16681 actcataccg tgatggatcc ggaggcatgg gtagggaaga ggttgcgagt cgcagtattt
    16741 atgcaggaac gagacgatag atggaggcca gcttccctat atgaatgact cacccatcgc
    16801 cgaaccatcg gccaaaacga tggtgttcat cgtgccgtcg ctcagccgct catccgcgca
    16861 ggatgaagac gtggtgcaac tcctgctatg tgccgcggcg agagtggaac aactgctatc
    16921 cgcttcacct ggcttggttg tgaaggcgac aatcctgtcc gttgatcaag acctcagcgg
    16981 gtgggtacag gttggagcgc tgttctctga cagaatttcg aagcacgtca cggttgaacc
    17041 cctgaaggag ccagcaacgc cctgcctcgc cattccagcg cataagtccg tctatcacgt
    17101 ccatgagttc ctgagggagc gccccttcga tgaggtgcac tgcctggacc gccacggcta
    17161 cgtatactac tcggcgcacg cgaagaggct tggcctgttc ttcctgacga cgcttttttg
    17221 tgttcacgtt gtggggggga cgatcttccg ccgcgagtgt caggatctgc tcctcgacga
    17281 tcctgatatc ctggcgattg atctcctgga gcgtggcacg gttgaacggg ccgacctcca
    17341 ctacattcac gatatcaaag cgtgggagtg gtatgacgag aaggttgtcc tgcacgccgg
    17401 cagcacgtct tatgatgtca catggcctgt ggatccgccc acatcggtgg tcgtggaagg
    17461 caacgagtct tcggaattac cagcactgat ctattgtgga ccacttggcg ccgacggagg
    17521 gttgccgctc ttttgcgatg tcgtggaccg tctcgtgtct cagggggaac gcctgaagca
    17581 tgtgacgttt gtcggcgcgg ctcacgcgat cggcggggtt gatgcggtca cgtacatccg
    17641 gctacggagt tccggctggc atctgccgat tacgatcaaa cgggatcttt cactcgctga
    17701 tgaaatgacc ttcctggccg gccttcaggg agtcgtcgtt tgtcatacgg ctcgacgtaa
    17761 ccaccttcgt tcacgtctga tcgtgggagg gctgcagaat gttctgcata tcagagcagt
    17821 aaacgaatct cgtgatggag cgcgcagcgg aggtgtcctc cccgggcaga taacccagac
    17881 ggtcactcgg ctcctacgtg cgcccctcca gcagtctcct gtctcgctcc ctccgctgac
    17941 gcaattgtgg aaagcggggc gcaagcttcc cgaccatgaa ggcgtcaggt cctctctccc
    18001 attgggtgta ccgaatgagc ctcagcccag ggtcagcgtc tgcatcacgc atttctcgcg
    18061 gccgcagaag ttacgcatgg cgctccaatc gctcaaacag cagacctatc gcaatttcga
    18121 cgtgatcgtg gtggacgacg gcagcccgga tcctgacgtc caaaaggaac tcgcactaat
    18181 tggagatgag atccggccat tgggctggcg cattctcttc caagagaacc ggtatctcgg
    18241 tgcggcgaga aacgttgggg cacggcacgc gactggagag ttcttgctgt tcatggacga
    18301 cgacaacgtc gcaaagcccc atgaactgag cacgtttgtg gcaatggcgc agaggactgg
    18361 agccgacatt attacgtcgt tttttgacgt atttgaaact gaggcaacgc tggaatcaga
    18421 tgggccgccg cctctccggt tcactccata cggagccgat ccggcattgg gtatcttcac
    18481 gaactgctac ggtgatgcca atgcattgta ttcgcgccgc gcgttcgaca agttaggagg
    18541 ctttaccgaa gatttcggcg tcacgcacga ggactgggag ttattctgcc gtgcttcgct
    18601 cgaaggggtc acactgctct gcattccgga accgttgttc tggtaccgca tggaccagag
    18661 cgcgatgttc cggggatccc gtacacaact gcataaaagc accaatcttc gccggcatat
    18721 ccggccctac ctggaaaagc tgccacgata tcagagcaat ctggtgcaac tgctgcaggg
    18781 actttccacc acattgcctc taaccaccgt cggcacggtc tcccgcaatg ccgcgccact
    18841 ggctctccgc cagcccgatg ccacgcttcc gtatggccgg gtcgctgtga tcactcgaac
    18901 gaaagatcgc ccccttctgc tgcaccgggc cattcgcagc gtgctgtcac aaacattcaa
    18961 ggattgggtg ctggtgatcg tcaatgacgg cggcgaccca cagcggcttg agaaggttgt
    19021 ggacgaggtg cgagaggagt tagcagaccg catcttggtc gttcatcatc cgatgccgct
    19081 cggcatgcaa gcggcatcca attccggcat tgcccattgc gacagtgact tcgtcatcat
    19141 ccacgacgac gacgattcat gggaccccac gtttctcgct cgcaccgtct cttatctgga
    19201 tgatcatggg tggaatgctc ggctaggcgg ggtgatcacc tggtcatggg tgatcatcga
    19261 agaagtggcc gacgatggtg cagtgaaagt tcacaatcga ttcgttttca atgacaagct
    19321 gcacaatgtc gccctcatcg acatgaccgt ggaaaaccgg tttcctccta tctcattcct
    19381 ctttcgtcga gctgcgatgg atcacgtcgg tccatttcga tcccagcatg ggccgctggg
    19441 cgattgggag ttccaccttc ggctcctgca gcacttcgat gtcgatgtga tccctgatcc
    19501 actggcgaat taccatcatc gcaccaacac cacgatcgga atctatggaa actccgtcca
    19561 tgcacataaa gatcaacatc aggcatcgcg aattcatctg ttgaatgagg cgctgaggcg
    19621 tgatctggat tccgggcagg ggttgtccct ggcgcaactc ctgaccctcg gcgaactgca
    19681 tcacagctca aaagctgagc aggccagaga atttcagcgg ctgcacgatt acctgtggaa
    19741 cattgaccag cgcgtgcaag ctatcgccac gcaggtgcac tcatccaaac atgggctccg
    19801 tgcgaaaagc agacgcaatc tggtgtcgaa cggggatttc cggcagtggc cagggctggg
    19861 tcccaaccag tttggtcctc acgagacgta tacgtttctt gatgtcagtc ccgggtgtgt
    19921 tctgtgttac gacgggcgcc aggtgtcgta tcgtttggag caacgcaagt ggacgactga
    19981 cgggcagcag ttggcgttcg gcaaaacgtt tctgcatatc gaaaacgatg ggtacacgaa
    20041 gggtggatca tggttcgcga tcgaattcat gattccttcg gcattactcc tttccggcca
    20101 cacgattacc atctcgggag tctcgcgcct caatgcccta cagggctgga tcggcctcgg
    20161 gggccggtat ctgtttggcg acggccgtca gcttgactgg cccgatcatc gcatcgacgt
    20221 cgcgtcggac tttgcccgat ggacctgtac cgtgatgtgt ccggccattc aggagaccga
    20281 ggtggggcac gggcatcagt cacggattct cctcaagctg cctcacaatc aacccttcga
    20341 tttcgatctg accaatctac aagttgagct gggcagcgaa tcgtctgact ttgaatacag
    20401 tagcgggaag gtgtccctac ggcacagggt tcatctggtg ctgcgagggt tgaagcgaag
    20461 gctgcgggcg gcgaaacgcg cgataggatg agttcgaact gcgtcgtgaa cagacatcgt
    20521 cggaggtaca cgtgtcgggc atctcgtgga atttgattcg tcatctggtg gccagggact
    20581 tccgcatccg gtactccgga tcagtcttgg gtgtcgtctg gtcagtgctg atacccatgg
    20641 cccaactcgg ggtcctggtc ttcacgtttg gcagcgtggt tccagtcaac atcgacgact
    20701 atcccgcgtt cgtgtacagc gccctcctgc cgtggacatg gttcagcgcg tgtctcgggt
    20761 caaccggatc gctcttcttt agtcatcgcg acctcgtgcg gagaccgaat tttcagccca
    20821 tcatcttaac cgtcgtgaat acgttgtcga atctcgtcac ctttctgttg agcctcccac
    20881 tcctgtttct tctgctcgcg tggtatcagc ggagcgtggc ggcgagtctt gtcgcactac
    20941 cggcactgct ggtcctgcag gcggtcatga cggtgggatt gagtctcctg gtgtcaacgt
    21001 ggaatgtgtt ttaccgggat gtctcccaac ttgtgaatat tgtgctctcg ctcttgtttt
    21061 tcctgacgcc gattttttat cgcccggtag tggaatccaa gtacgccatg atctttcagt
    21121 tcaatcctct ggcggtgctc atttcctcct atcggaacat cctttttgaa ggacgtctgc
    21181 cggagtggga tgcctgggcg cacatcacgg cagtgagtgc cgcgctgctg gtctgcgggt
    21241 atctcgtgta tcgccatgaa ttgccggacg tcgtggacac tgtctaggag agaccgatgc
    21301 acgctgccat gacggtcacc gacttgtcga agcgctaccg tatctcacgg cacaaggtga
    21361 ccacgcttcg cgaaacggtc gatcgctgga tcaagggccg tcaggatgtg acgcggacga
    21421 tgtgggcgtt gcgcgatgtc tccttcacca tcgaacaggg acgggtcttc ggcatcatcg
    21481 gccataacgg agcgggaaaa agcacccttc tccgactgct ctgcggcctg ggccggccga
    21541 cgtcaggccg tatcgaagcc gggggatatg tgagcggcat tctggaactg ggcggcgggt
    21601 ttcatgccga gctgacggga cgacaaaatc tcatgacggt gggcatcctc aatgggctga
    21661 cgccagccga ggtgaaagcc agggagcagg acatcatcgc cttttctgaa ctggaagact
    21721 ttatcgatca ggcggttcgc acctattcga acggcatgta ccttcgtctc gcattcgccg
    21781 cagccatcga gtttgatcct gcgattctga tcattgatga agtgttatcc gtcggtgatg
    21841 agcggtttca gcaaaaatgt ctcgatcgca ttgcggcctt ccgggcatcc ggcaagacgc
    21901 tggtcattac gtcgcacgat acggatcaga ttcagagact gtgcgatgaa gtgctcgtcc
    21961 tcgaagaggg ccgcgccatc atgcagggcg accccaagag cgcgatcgct tgctaccacg
    22021 acctgatgcg tcaacgtaca gaacgccggg ctgctcacat tggtggcggc tctacgcgat
    22081 cactgacgac tgcaagcggg acgaggcagg gcacgcaaga agccaccatc gccgtggtcc
    22141 ggttgtgccg cagcgacggt caggccgtgg agactatacg tagcggcgaa gggatcctgg
    22201 cggaattgga gattgatgcg ccaccctcaa tcgaggactt cgcgctcacc gtcggggtgt
    22261 tcaatgaggg gcatgtcaaa tgttttgaag ccaccatcgc atcagtacaa gggacattgg
    22321 gcaaagtgag ccctcacagt tccatccaat gtcatctcaa acacctgcca ctgttgtccg
    22381 ggtcgtattt catcaacgtc ggcatttacc cgacggattg gtcctatgtc tacgattttc
    22441 actggcaaat gcacccggtg acggtatttg acgagcgaac gagcaactcg caggcgggag
    22501 gaattgtcgc tgttgaaaca cattggacga tcatctctcg cggtgatgta tgagaccggc
    22561 tattcgcgcg gcagggttgg tctgctgctg cgtgatcatg cccctgtggc acgtggttca
    22621 ggtgggcgcc gagaccacga ccgcaccggc gagcccgcct cgcatgttga ccagggaaat
    22681 tcgttatcac atgcccgaag caggggaagt gtggctggtg tggggcgtga acgggtggca
    22741 taggctcccc gaagcggcct ggccgccggg aacggtgttg gggaaaaccg gactcatgac
    22801 cactcggatg atcgaacaag gggacgcgtt cgtggccact gtcgcggttc cgaacggtac
    22861 ggcattggac tattgcttcc tgctcaccaa aaagcgcgag gcgtttgata tcacctggcc
    22921 gctctgcgaa ggaaattaca gcgaggtcgc gacgcgttcc ggtgtgacgg aaatcggatc
    22981 gcgactgtcg ttggctgtgg tcacacagga gtttcattac cacatgcccg atgcgcaaga
    23041 ggtgtcgatg gtatggggcg tgaatggatg gtctcctgtt ccggagtcac tgcgtccgct
    23101 gaacacaaag atgtctgaca atctcatggt gtcacccatg agaaagagag agcaggagtt
    23161 catcgtctcg gtgcaggtgc ccgtaggggc tacgatcgac ttcgggtttc gaatcaccag
    23221 gtccgccatg gggtccgtca atatttggga gggcggaggc gccgaaggat ttcatgaacc
    23281 tgtgcgaggt ggttcatcga tccgggtgaa aagcaatgcg atcatccttc cacgcggacg
    23341 tccctctcgt gacgaagaca atggatggca tgtagcatgg gcaattgtcg gcgcagtgtc
    23401 cgcccctctc ctattggcgg gactgctggt gatgttgaga cggcgccaag cgcggcagcg
    23461 gagcgcgaat cccttcaacc ctcgccggga gaagccaagc tcagcactgg acggccttct
    23521 gattcttgcc gctgtgggca tcggcgcctt cggtgccgag caaatgcttc gaaacgtata
    23581 tccccacgaa ggattcggga ttgcggcgga agacgagtgg ttccggcaag ccccctatag
    23641 tgccaaccaa ttgttcacaa tcgatcccac actcggcata cggccatggc tgcggacggg
    23701 caggtatacg gagtacggaa ccgtgcccaa tatgtatcgc ctggccaaag attcgcgaca
    23761 tacccggatc ctgtttgtcg gcaacaccgt gacgtatgag ggcacattgc ttcacgcctt
    23821 aagggaactc cacggagaag accggttcga atattggaat gccggagtgc cgacgttcaa
    23881 cacggttcag cagattgcct actatcatgc gtacaacgcg cgtaccgcgc ctgatcatgt
    23941 catcttgacc attcaaccgg atgacctcgg gaccatcccg attgtcttta ggaatcacac
    24001 ggcggaactt gaggtgcacc gtcctgcgat cccccggaaa gaccttgata cggagctcta
    24061 cggatcgtct tatctgtatc ggtatgtgaa gggactcctg atctcacctg aggagaagct
    24121 gcatcgcctg tggcaggagt accgcgacag cgtaaagagc ttcagcgaga ggctcgctca
    24181 cgaccacatt cgcttgagtg tcgtagtgct tccggtcctc gcctctcagc aagagtggac
    24241 tcaggctgag agggaccgac gacaagcgct gttctcagtg ctcacggagt tacagattga
    24301 acactacgat cttgctcagg cctttgaacc gggccgagcg gagaacgcag tacttcctcc
    24361 gatgagcaag gaaagctggg cgccttcatc tgaaatggtc tccgcctttg ctcaatatat
    24421 gactcacgaa ggactctttc gcaccaagga acactagcat gagtcctcat catacgcatc
    24481 gccatgagaa tcgggccaga tccaatcacg cggatgagag cacgcatgat gtccaaaggg
    24541 gtgattcgtc agaatccatc tccggcctag tctccatcgt gattccctgc tatcagcagg
    24601 cacactttct cccggacgcg atatccagca tccttcgcca aacgtatccc gacattgaga
    24661 tcatcgtggt cgatgacggg tcgacggatc atacgagaga cgtggcgctg tcacatcccg
    24721 gaatccggta tatcgctcaa aagaacgcgg gggtgtccag cgcgagaaat accggattcc
    24781 gaatgagtcg tggtgagtac attgtctttc tcgatgccga tgaccgactc atagcggacg
    24841 ctatcgaaat cggcacacgc agtctcgccg agcacccggc ttgtgcgttg acgttcggga
    24901 catttttcat gattgacgcc gagggcaccc gccacaaccc gtcctatccc ctgaacgccg
    24961 tcacttacgg ctataaggaa ctacttgaag aaaatgccat tggcaatccg ggggtagcgc
    25021 tctatcgccg atgggcgctt tcggtagtcg gcggctttga tcacaggaac gggcccgctg
    25081 gagattatga tctgtacctg cggattgcac ggttgtttcc ggtcgcgtgc catcggcgtc
    25141 cggtgatcga atatcgccgt cacgggggca acatgagcaa tgatccgggg gtcatgctca
    25201 aagcctgtct ctccgcgctc aataagcagc gcgcatttat caagaaccaa ccggatctta
    25261 ccctggcgat gcgtcgcggc agaatcggct ggaagctgta ttacggggag ccgttagtca
    25321 gtaaagtcca agacgaattc tccaatagaa actggaaaga agggttgcgc ggactactcc
    25381 aactagccat ctggtatccg gagagatttc tgacaggact gagccgtaaa gccaccaaac
    25441 tcaaaaacag gatgcgctaa ctggccatca gtcgtccgtc aggcgtcggt tatgaagtcc
    25501 tgcccgccaa aatccgcttg gcgttcgcgc ctagccctga tggtggtcct ctgtggcctg
    25561 ccgggttgtg tgactgatgc gcccaccctc accgaatccc cggatgaagg gcggaaggtc
    25621 ttgctcatgg ggaatgtggt cacggtgctg accggagaca gagcgcgaaa gttcgaacca
    25681 gcggtacggg atatcgaatt gattgagcag aatgcaggca cgcggtatcg agtccaggtg
    25741 gatggccccg ataaaccgtt cgccgtgttt gtgccaccag gccgctatga cattacacgg
    25801 gtgaaaattc acgaggggcc atttttatcg atcgcacatc tcacggcatc gttttcggtg
    25861 gaagaggggt cgccgatatt tgtgggaacc tggagattcg gtgtggactc gccccggtat
    25921 ggtcgcatgg tcgctgtctc catggtgctg gacgacgaag cccggcaaca ggcggagcag
    25981 gagctgcgcg agacctatcc agacttggtc tcgccccgaa tgctgaccgt cctccccgcg
    26041 ccgtcagagt tgcagacacg cttgtatgaa gttgctcctt atccgaggat ttcgaggtac
    26101 tttcggcgcc actactggtg acggtcatgc gagagatgct ttccgaaaaa gaggagaggg
    26161 ccgcggcgcg cgattccttc atcggcgaag ttgttccatc gtgcattggc gaggtgcttt
    26221 gtccggacga aaccggagga gttttgtgcc atggcggaag cggtcgtctg tgacgtggtc
    26281 gaaactcacc tcgacgacga tttggggcga gagcggcgtc catgttgttg atcgttcggt
    26341 tgaccaccgg ctgggcccac cgggagcctt cccgtcaaag cctggctcat gaacgagcgc
    26401 ttcgagtgtc ttggtcagcg aaggcttgtc tgctttcgca attcccgacg taaagccgac
    26461 gtgattcagg cgcccgttct tatcatacag tcccagaaga agtgatccga cctcctctga
    26521 acctgagcca taccggaatc ctcccacgac gcagtccgcc gtgcgaatcg gcttatattt
    26581 ctgcatgaca cgctcgcccg gctcatacgc ggccagggtg tgtttggcga caatgccatc
    26641 gatataccaa ccggtcgatt tgagccaggc catggcttca gcgatcgacg ctgtctgcgg
    26701 ggataattgg agggccggtt ctttcgcgca gtatctcgcg taaaaagatt cgagccgaag
    26761 gcggcgtgcg gcaaaaggtg ctgacatgac ggccgagtct gtttctgctt ccagtatgtc
    26821 gaaaaggaca aatgtcgccg gctgtttttt tgccagcatg gtcactcggc tcgcagcggg
    26881 atgcagtcgc atctggaggt cggtaaatga atagccctcc tcgcctttga tcagcagttc
    26941 cccgtcgagg acgaaattat cggccttcag cttggcaaga acgcgcacga tgtcggggaa
    27001 atatctgtcc aacggtttgc ccgatttcga gtgcagtgtt acggacgtct tgcgcttata
    27061 ggcgagacag cgaaacccat cccatttcgg ctcatatcgc cattcgtgac cctccggcaa
    27121 acggctgacc agcagggctt ccatcggagc gaatgtaggt gcagccacgc gttcagaacc
    27181 tttctgtctt caacaccggc agctgctgga tcggcagggg tttcggtcgt tgttgccggg
    27241 cgatccgttt cagcactgcc gtcataccga attgatcagc gctcttgagc gtgccgagat
    27301 cgcgccactg caacggcacg gccaccggtg cgccgggtcg ggcccgtagc gaataggcgg
    27361 caatgctcgt ggccgtatag tcattacgaa agtagtcgat gaatatcttc cctgcccgtt
    27421 tggatttggt catggtggcg acaaatctgt ctggcgcctc ttcgaccatg gcatgcgcca
    27481 acgtcgaggc ccagcctttg acttcgtccc aacgtctggt gggcgacagc ggcaccacga
    27541 catgcaggcc tttgccgccc gtgcacttca gcaagctcgt gagtcctgac tttgttaagc
    27601 gctggcggat ttccgtggcc gcttgtttga ccgctgagaa aggaacggtc ggatcgggat
    27661 cgagatcgaa aatcatccgg tctggcgtat ggatgctgtc gatcgtcgcg ccccatgggt
    27721 ggatctcgat cacgcccatc tgaatcatct gcatgagacc catttcgtcg gtcacataga
    27781 tgtattggta gctctgccct ttatagtccc acgcaaatgg atgcacatgc ccgcctaatc
    27841 cagagccgac attgcgctga taaaaacaat cagcctggat accgctcggg catctcaaca
    27901 aactaatggg acgccgggtg atgtctcgca agagaaacgg cgcgacggct gcatagtagc
    27961 gagcgacatc gcccttgcaa atccgttcct ccttgtacac cacgcgatca ggatgcgtga
    28021 tggtcactcc atgcagaata agggcttcgc ctgggtggtt cttcatcggc ttggcagtcc
    28081 cgctgtgcca gtcatcgacc gtggcggttg ttctgcgtat agggaatcga gcctgccgag
    28141 acggcagcat cttgatctat gaggacatgc gggatgtggg ttttgtcctg gcaaaagccc
    28201 cagtgactga agctgcggcc tgtcgccgct agggattcac ctaagtttca ttcggaaaag
    28261 gatggcccat gatcggcaca aaaccttatg gccaaagatc tagacatcca ggacgacctc
    28321 ccatttcagt accgtcattg gagactgcag cgggtgggat ggtgggccat tgcctgtatc
    28381 ctttctgccg gtctcctcgg gttgttcggg caccatcctc tttctcgaac aacggtgcag
    28441 acacaagatg gcacgctcct ggtcacctat gatcgtttcg gacgcgccac cagtgacgct
    28501 gaagtcctca ttaccgtgac gcccgcaaag caggaggagg gagcgtttcg ggtctggttc
    28561 gactcggaat acctggatgc cgtacgcgtg gggtccgtgt caccgctgcc cctccgaggt
    28621 gaggcgcgcc agggtggtcg cgcgttcgtc atacagtcgg atggcggccc ctcgacggtg
    28681 ttgttctctg ttcagtttca cacgttcggg atcattcgag gccacgtcaa aatcaacgat
    28741 ggtaaggcgg tcccgatcac gcacctggtg tggccgtaga gggaggatgt atggatgcga
    28801 ttctgcgggg attcataatg tacctgttcc tgctggtgtt gttccggatc gcagggcggc
    28861 gaacgctggg ccaaatgacc aatttcgatt tcgtgctgct cttgatcatc agtgaagcga
    28921 cccaaaatgc catgatcggg aatgatttct cggtgaccaa cggtattctg gtcatcttgt
    28981 ccctcgtggg tttggacatt ggcttttcaa tcctgaagca gcgattcccg atcttgaatc
    29041 gtcatctgga tggactgccg ctggtgttgg tggaccaggg gcggcccgtg caggaattga
    29101 tgcgcaagac cagggtggac gaagaggaca ttctgttctc ggcccgcgag aaacatggcc
    29161 tcgagcgcat ggaacagatc aaatatgccg tgcttgaaac caatggtgga atctcgatca
    29221 ttcccaaatc ggcggagtag tgcgtgctaa agaagctgtc tcctaggccg cgatcgtcgc
    29281 ctcatgctgg ttccctggca ttgcttccac tgggcctcat tgctttcatt ggactagctg
    29341 gctgcgtggg gcttgattat gccgccgatg acgagctggc ctcacgaatc gatcaggcgc
    29401 tactggccac agatgaactg aatctcagcc gcatcgaagt ctccgtcgaa ccgggggtga
    29461 tttatctcag cggcatatcc gacgatcacg acagtaaggt tcaggcagaa caggcggcgc
    29521 aggcctatgc ggaaggcaga aaaatcgtca ataaaattga ggtcgatttt tgatgcctca
    29581 cattgcctcg tcatctcggg atgacatgcg gttactggcg acgaggactc atcgtttcca
    29641 gcacgggtac cgtgacaaag cctgccctgc cccgcgagcg cataggtgcc tggcggttct
    29701 cgtcgcgtgc tttctttgta tcatgtacga agaccaaggc ggcgcggttg agctctggca
    29761 gtatggcggg tttgccgatg tcagctacgc ctctacgggg tatcatcccg aaaatcatca
    29821 gtggcgcagc aaggaaacat ccacgaggac aaatgagctg gctccgaata tcggactgct
    29881 gtatgtgcga aaagatcctg cagagcagtc ccgctgggga gttgagttgg ccttccaagc
    29941 cggatatgac accgatgatc ttgtccctga gccaaaagcc gacgggacac gacctgtgtc
    30001 aggtgcggat accttgcgtc atgtggctcg ggcgaatgtc agttacctgg cgccgatcgg
    30061 gcgcggtgtc accttctcgg ccggtctgat gaaaggttcc aaaacctatg aagagtttta
    30121 tgccaaatac aacctcaact acacgcgggc ttacattacc gattacaacc ctaattttgt
    30181 gatgggattg ggggcctcct atcccatcac caagtcactg gaactcggcg tctatgtgat
    30241 caatgcgtac cggcaccttg cgcataccaa tgatgctccc agttaccttt ccaagatgga
    30301 gtggcgcgta tctgaccatc tcacggtcta tgaaaacctc tactacggcc cggaccagcg
    30361 ggcgacctcc gtggactatt ggcggacctt ctccgattcc accgtggagt ggcgcaaacc
    30421 ggactggcgc gtggccttgt cgtataacgt gggaacagaa aagatggccg atgtctccgg
    30481 ctctccacga gccgtgtgga tgggcgccgc cttattcacg caacgacacc tggttggccc
    30541 ttggagcatc gctgtccggc ccgagtgtta ctgggatccc caaggccgga tgacggagca
    30601 tgagcaattg ctatgggcta ataccaccac cctcgaatac aagaaacacc tgggacaaca
    30661 gctcatcatc gtccgtttgg aacaccggta tgatcgatcg accgggtcgc aaggcggatt
    30721 cttccgcgac gggttctctg cgccgggtgt gccgcggctg gcggcagacc aacatctcac
    30781 gatcctgggg gtgatactcg ccttcgactc cgcctagcag cccgttttac gggggcagac
    30841 ttcgacaaat gccaggcaca tcgagggatt gctcaccctg tccgccgcct acagcaccta
    30901 ttcgctcatc gtcatatgcg tgaacaagcg aggcgcaagg acatgtcgcg ttgcttgttg
    30961 ctaggcgcgg cctatggtac tctccagtca ttgcgggtcc gagaagggga ctacgcaact
    31021 tgccaatcgt taacatgagt atgatcgtct tgcgttgtcc agcctctcgt cttccaaaag
    31081 tattgatcct cctgctgacc tgggtggtgg ttgccggtct ctcctgggca gacctggttg
    31141 gttctcaagc agaaccgacc ggggcattgg tcgatgcgca ggtcgcgacc gaactggatt
    31201 tggacgagct gcgggatgat ggcacggcca tttccctcac cgaagaagaa cttcccgccc
    31261 gcctttcgcc acggacccct cccttctttc agatcggcat tccgtccccg gatgaccatt
    31321 cgctaccaac ccgattgttg ctctccaaac tgtccgtcta tcgattgtaa cgcgttctct
    31381 ttcgcttcaa ggtacggtcc ggtgactcca acttcgtgtg aggacgaggc gccggttgtg
    31441 tgaggcttgc attgggagcc cggtgggcac cggagcgagc agggaaggaa cgggacgtat
    31501 gatcgatcga attgtcgggg cggcgttagc acagcgcctg atggtgtgtt tcgccggtct
    31561 cgcgctgttg tttgggggcc tctacgcctt tcacattctg gatgtcgtgg cctatcccga
    31621 tccatcgccg ccgatgatcg aggtcatcac gcagtatccg ggctggtcgg gcgaacagat
    31681 ggagcgcgcg attacgctgc ccatcgaaat tgctctccag ggcatgccgg ggctgtcgga
    31741 gattcggtcg ttgtcgattt tcggattgag cgacgtcaaa gtctatttcg acttcggcac
    31801 cgactacttt cgagaccggc aggaaattct gaaccgtctg caactcaccg tcctgccgca
    31861 aaatgtgcaa cccaccattt ctccctggtc ggccatcgcc gaaatctttc gttatgaatt
    31921 gaccggcgac catgtgtccc tcaccgatct aaagaccacg caggattggc agattcgccg
    31981 cgagtttaag cgggtgcccg gcgtcatcga tgtgagcacc tatggcggaa cgaccaagga
    32041 gtatcacgtc gagttagatc ccgggcagct catgagttac aacgtgacgc ttgaccaggt
    32101 catggatggc ctggccaaga gcaacaccga tgtaggcggc aactacctct cgatggggga
    32161 gcaaagcttc aatattcgcg gcatgggcct gatcaagaaa ctcgaggaca tttccaacac
    32221 ggtcgtgacg cagaaggaag gcacgccggt gttcgtgcgc aatctcggga agaccagcat
    32281 cggttcccgt gtgcgcctgg gcaaagtcgg catcgatgat cgcgacgatg ttgtcgaagg
    32341 cgtcgtgttg ctccagcgag gcgccaaggc cttgccggtg ctcgacaagg ttcacgagaa
    32401 ggtgcaggag ctcaacgcca gaaagttgcc gcagggtgtg gcgatcaaga ccttttacga
    32461 ccgcacggta ctgatccata ccaccattga gaccgtcatc gatattttga tcgcgggtgt
    32521 cgtgctggtc tcgatcattc tctatgtgtt cctgggacat ttccggaccg cgatgatcgt
    32581 cgcgctgacc gtccccgtgg ccctgctctt cacattcggg atgatggtcc tcagcggcca
    32641 gtcggccaat ttgatctcgt tgggggcggt cgactttggg atcatcgtcg attcgaccct
    32701 catcatggtc gaaagtattt tctatcatct tgcgcataaa tcttcggccg gcgtgacggt
    32761 gccgatgcat gtcatgcggg cggcgcggga ggtcgggcgt ccgattttct tcgccacgac
    32821 gatcatcgtc atcgcgtttt tgcctctctt caccatgaca ggggtgccgg gaaaagtatt
    32881 tgcgccgatg tccctgacct atggctttgc gttgaccggt gcattgctga tggcgttcac
    32941 cctggcgccg gcattgtgct cgcttctgct gactggaccg atcaaagagc gtgacacagc
    33001 ggtggtggaa ttcttgagcc gccgctatat ggctttgctg aattgggggc ttcaacgcga
    33061 atggttggtg atcggcatcg cgatcgtgac gttagtcctc gccatggcgg ccgtgccctt
    33121 catcggcggt gagttcatgc cggccctgga agaaggtaat atctggatgc gcaccacctt
    33181 ccccgtggac atttcgttcg aacaggcggc tcgcctggtg acggacattc gcggcatctt
    33241 caggcagttt ccggaggtca tcagtgcggc ctcgcaatta ggccgacccg acgacggcac
    33301 cgatcccacc agtttcttca atgccgaatt cctggtgacg ttgaagccgt tcaaggagtg
    33361 gcgggcggat gtgccgacca aaaaagccct ggtcgatcaa atcgagcaac gcctcgccgt
    33421 gattcccggt gtgaccttca acttctccca ggcgattcaa gacaatgtgc aggaggcgat
    33481 gtcaggtgtg aagggagaga acgccgtcaa actgtacggc agcgatctcc agacgttgga
    33541 gcaactggcc gcacagatcg agctggtcat gaaggatgtg catggcgtga aggatctggg
    33601 cgtgctccat ctgttggggc aacccaacct ggtcattgag gtcaatcgcg aggaatgcgc
    33661 gcgctacggc ctcaaagtgg gcgacgtcaa cgatgtggtg caggcggcca ttggcggcca
    33721 ggcggtcacg cagatctatg aaggggaacg ctggtttgat ctggtggtgc ggtttctccc
    33781 tgagttccgg cgcgatatcg aatcgatcgg gaatatcgtc gtgagtactc ccgatggggc
    33841 caggattcca ctcaagcaat tggcctccat cacggaacag acgggggcgt tcatcgtgta
    33901 ccgcgaaaat aacgaacgct atattccgat taagttcagc gttcgaggcc gcgacctgga
    33961 aggcacggtt cgagaggcgc aagagcgcat cgagcaacag gtgccgctcc ctgccggtta
    34021 ccggatcgaa tggcatgggg agttcgatca gttgcaggag gaaaaggcgc gtctcgccaa
    34081 gatcgtgccc atcactctgc tgctcattct gtttctcgtc tacctcgtgc tgaacaatgt
    34141 gcgcgatgct ttccttgtcc tcgcggcggt ccccttctct ctggtcggcg gtgtgctggc
    34201 cttgctggtc accggcacgc atttcagtat ttcggcggca gtgggattca tttcgctctt
    34261 cggtgtggcg gtgcagggcg ccttgattct gatcagccgg atgcaggaac tgttgcggga
    34321 agggtatgag attcgcgacg cgatcataaa aagcgcggaa gtccggatgc ggccggtgtt
    34381 gatgacctcc ctggctgccg ccatcggact cctgcccgca gccattgcca ccggtatcgg
    34441 tgcgcagtca cagcaaccct tggcaagagt ggtggtggga gggatgctga cctcagcggc
    34501 actcattctg ttagtgctgc ccgtgctgta ccaattgcta caccgctacc ggaagccatc
    34561 gcgctcgacc ggagcgacag cctctgcggg aacagcaaac cagggccatg gttcgcatga
    34621 atgaggtatg gggccggcgt gcggcgacca ttgtgctcaa gttcttccgg agcgcctcat
    34681 gagcgatcgg cttgaggaat tgcgtcggcc cgcaccacga accgcaaggg gccgccggtc
    34741 gtgatcgcgt cgaagggaaa acaggtgacc aatataagtt ccgcgcgttc gtcgctcgtc
    34801 gcaatgctgt cccgctgcga atccatgacc tgccgctcgg tgactctgta gcggcgggtc
    34861 gttccatccg ttcccacgat ctcgagccgg tcgtccggtt gcagctcctt caaaaattgg
    34921 aaatgcgtgt ctcggtgccc ggcaagcatc atcgtgcctg tctgtcccgg cagggcactt
    34981 gacccgacgt gacccggccc gaaggccaac gtccgtccat gggcgccggc cagtacgatc
    35041 agatccacag acaggcgtgg tatccgcaag cgtgcgacgg gccaggtgtc ggcccagggc
    35101 cagggcttcg gcatggcctc tccttccaca gaacgggtcc aggcccgctg cagcagaagc
    35161 tgcgcgagcc cggccttggc atacatccat gatccttccc agacctgcca cagtccgatg
    35221 gcgagaaggc ttgccatcaa ccaaaccacc gggcgtgacc ggtgccaggt tccagtcatg
    35281 cgacctcgtt ccgcagtctg cggaccagcg ccgccagcac gagtgctgac aatcccagca
    35341 ggagttgcag ctgccagccg gtggcggtct tcggcaatgc gctcagctgc atgttggcca
    35401 ggttcgttgt ctgccccggc tccgctccag gaacatcggt tggtcgagcc ggtgtcacat
    35461 cgactgccac cagactggtg tattggctga caaggtggtg ggccaacgcc acttcgatca
    35521 cggatgtttt ggtgacctcg gcacggccct ctttggtggc ctcatccatc agggatgaga
    35581 ttttttgcct cgcccaatag acggaaagcc ctccttgcgt cgcggtttgg ttcaacgaga
    35641 ccggaagcga ccagggacgg ctccctacct gcccatgcaa ggttgcgtgc gacggcacgg
    35701 catcggcttt catggcgagc acaatcggct caccttcata caggtcggcg actgttgccg
    35761 ggtattgttc cagcccggac catccggcct gatcgacgga gacgtccgtc agcaccgggc
    35821 gttccagttt tctgaacagg cgctccaact tctgttcgac ctcctccact ttaccgatat
    35881 aggtgaaggt gcctcgtccg aattcggcag ctttccgcat caggtggcta ttgggtgtgg
    35941 atccgatacc gatcgtgaac agccgcctgg tgccgacacg ttggtgcagc agctcgaaca
    36001 attcctcttc gttcccgacc tggccatcgg tcaataagat gatctgttgc agtctggcgc
    36061 tctcttgcgg gctcttgagg gcttgccgca gggccgggag cacttcggtc ccgccatcgg
    36121 ccgagaggtg ctccgtatag cggatggcct gtttgatggt cgtggtcgtc accggctgag
    36181 gaacggcaaa cagcgagcgg accgtgtggt tgaactggat gatgttgaag cgatcctgca
    36241 tggaaagccg tggcagcgct gcggccaagg cacgtttcgc ctggtcgatc gacgggccgg
    36301 ccatggaccc tgaggtatcg atgatgaacg taagatcgcg aggaacgcgc ggcgccttct
    36361 cgtcatgctg cgtcgggggg gcgagcatca gcatcgcata ggtctgccca ttcttctgct
    36421 cagtaaagac cgtcgcgatc ggctcggtgc gggccacggg atgccagctg agctgaaagt
    36481 cgcgatcggc cggcactgca tcggcccgga gcgtgacatg ataaccgccc tcggcatccg
    36541 ggatgctaat gatgggatga aacgatgatt ccaccttatc gatcgggaaa ccgggatgaa
    36601 gcgtcaatga aaggctgagg ggattgatcg cgccatagcg gggtgattgc atcggcgggg
    36661 tgatacgcga ggcgtcgggg acgcggtctg tatccagcat cgtgccggat cctgtggccg
    36721 cctgcccttc gataatgacc ggcgtgccgg ggatgtagcg ctgtcccacc gccatgggaa
    36781 agcgtaggtg aaattgttcg tcgtcatacc ggacggtttc ctggtactcg atttcgatgg
    36841 tgatgtgctc gccgggtccg atattggcta cggaggtcgt gaagatattc ggtcgttcct
    36901 gatccaacag gctcgttcgc tgtccctgct gtttggcctg ttcatagacc ttcttggcta
    36961 cggcccgttc tttaatctgt ccttcgatga tccgctcgcc gacgtgcatc cgcaggtgat
    37021 cgacggcagc tgtttccggg agagggaaga cgtagatgcc ctcaagccag tcgccttttc
    37081 tggtgctggg attcgtaaat tcctgacgga ccgtcgcgcg ggcgatggtg ccggtgacgg
    37141 caatgtgcac gtcggtcttg agaacgggag ccggggtaaa tcgaccggcc tggtccgtgc
    37201 ggaacagcag ggtcccttcc gtgacctcat tgatgcccat ggtgggaacg actccggtac
    37261 tcaacgtgac cggcgattcg gccgagccgg cgtccgtggg aggagttccc accccagagg
    37321 tggcgagtgc catgcagacc atcaggatgc gtgcacatct gtgtagtcga gcgcggggga
    37381 gaaagaacca ttcattcagc atgcgatcct catattgttc gatggaagtt gtgcgtggtt
    37441 gctggtccct gggaaagacg aggtctttcc cagggagagc tcgacgtcac gttagttgcc
    37501 ggttgctgat tcgacaggac tgtctgcccc gttggaggac gcgccgaccc cagtagggtt
    37561 ctcgctatca gattcggcgg aagccgattc catcgacagg tcggtggtca gggagaatga
    37621 atccgtgact ggttcggtga ttacggcagg aatcaccatg tgctcctggc cgatcttgcg
    37681 catttccaga tgcacccgtc ggttcatctg ccggcaggca tcgctcttgt cgatgcacag
    37741 ggcgccttct tcacccaggc tcacggtgcg gatggccgat tccggcacgc ccagcgagat
    37801 gagctgctgc ttgaccgtct cggcccgctt catgccaaga atcttgttga agctcatcga
    37861 accctgttgg tccgtataac cttgaagcaa cacgccccaa tccggttcgt ttttcaggaa
    37921 ctctgcatgg cgctggaggg aggccttccc gtcgtcggtc aagcccttgc gtccgacttc
    37981 aaactggatg tcgtcgtgca ggatctctgt gctcctgctc gccaggggga ttgtttcgac
    38041 gtgagtgacc ggcatcgcgg ctccccctgt caccttctcg gtcgactcct tgagaacctg
    38101 ggacacctgg gctacatcga gcgcttcaga cgatcgattg ctatgggccg cttcgtccgc
    38161 ctgggagtag taccagaagg cggcgacgac tatggcgagg aacccgacga gaccgctgag
    38221 gatatagacg tccttcatgt cccgatccgg gccgacgagg gtgggggcga ctggtcctgc
    38281 actgacggta gctatagggg atttttgcat ggtgcctgct ccttgcattg ttgagccgga
    38341 tcgctccggc ccgttggttg ttggtgaaga tttgcccgct gctgtcttgc ggggccggcc
    38401 tgccgatggt cacctccttc ctgccgaacg cccgccgttg ggcggtgcat agagcaaggc
    38461 ggaggccagc cgaatcgacg tcgcggacga tcacgaaacc cttgtgaagc aaggggttag
    38521 gtgaaacgca tcgatgcgtg gccaccgcga ttcatgcggg gactagcggg gatgcggggc
    38581 tatccccgca tggagactgc gtggtggatc aagcggaatg aggcggagat gcttcggtga
    38641 tccggatgga cctgactctt gcctctggcg agcgtcgcct gctaaaaggg gccgagccgg
    38701 ttgtgccttg gtcgaagttt cggatatccc gctcgatctg cagcagcaac cagccttcct
    38761 cccatcacgt cgtctttgca cccaggttca actcttggag agcatgagct ctctcgaagg
    38821 ggaatcgggt tgtatggctg tgcttgtgat cggtccggcg ccgatccagg aatttatttg
    38881 agagggatga gggctgctgt aagatcgacc aaaatccccg gtgatcgcct atgtctcaat
    38941 tcaggcaggg agaatcgttc gatgaagagg ttgtcctcgt ggttgttgat gtcgtggctc
    39001 ctcatgggtt cgctggttca agcagcggac tatcaattga ccctcggtca gggaatcgac
    39061 gtctgtgaag cctgcaaaca gaatctggaa cgaatgacgg tgcatcctgc ttgcgagcgg
    39121 gagtacagcg cgcaatttga tctggagtct ccggcatgga aacccttcga tgtggcagga
    39181 catctcgaag ccatggaaca ggtgttgtat ttcctgaccg ccggcagcga gtcagggaga
    39241 aacattccgg acgaaagccg atttgaggat acgctgtgga gaatcagcac caaggacgag
    39301 ccctgggcct attgggcgca agtggatatc aataatgatg ggaaggcaga accggttctc
    39361 aagctccatt cctcactgtg ccacgctcga aacgatggat cgattggtcg ggcctattcg
    39421 gctcccatcg tggtcctcac ggaaaatctc agcggcatcg atcacgaatt gacggatctg
    39481 gttcttcaaa atcctcgcca ggatggacgg gctgccgggg aaaccaatta ccagttgtac
    39541 ggcgtgttcc gctacaaggg gacgacctat tttgaccgtt gggatgatgc gggaagcggc
    39601 gatcaggcgg atcaatttac gttgagtatc tacgcatcca ccggggatac gactcgcaaa
    39661 ctctgccggt tgaaggaatt gcaagcgaag cgctggttcc ccggtttgcc ttgcacgtcc
    39721 cgtcaatgcc agaccgccag gccgctcccc gctcactaca tcccgtagcg cgatcactcc
    39781 ggcgcgccgg gtcacttcgg cgctcaacgg ctcttcaatc gccacaagga ggtcaactcg
    39841 gctgcgcggg cggcgcggag aggatccgcc tgttcggagg cgcgtggatg agtgggccgg
    39901 atatcggtct ttcccgcgac gacgagccct gcctgctcga aggtggcgag gagttccttc
    39961 ctggatctca gtgccagatg ttcggcgaga tcggagagta agagccagcc ttctcctccc
    40021 ggttccaagt gggcggctag cccattcaaa agcccgtaca gcatgcggtt ctcgggatcg
    40081 tagatcgcct gctcaagggg cgaggtgggc cgcgccggaa cccatggcgg gttgcagacg
    40141 acgagctggg ctttgccctc ggggaacaga ttggcttgcc gcacctcgac ctgatcgctt
    40201 agctccagtc gttgaagatt ctcacgggcg caggcgaggg cgcgaggatc ctggtcggtc
    40261 gcaatgatgc gcgggacgcc acggcgggcc aagattgccg ccagtacccc ggtacccgtg
    40321 ccgatatcaa acgccagcgt acaggcaggg agcggggcgt cggccaccag cgccacatac
    40381 tcgctgcgta tcggcgaaaa cactccgtag tgcggatgga tgcggtcgcc cagggcaggg
    40441 atgtcgatcc cgttctttcg ccattcgtgc gccccgatga ctccgagcaa ttcccgcagt
    40501 gagaccaatg cacgagccgt cgcggggccg taggcttctg tacaggcttc acggagatcg
    40561 ggcgcacgac ggaggcggat tgcgtaatca tcttccagag tgatcagaag catgcccagg
    40621 atgcgggccc ggcgtgcttg cgtctgccgg tgaaagtgaa aggactccgt gggagaggcg
    40681 ccgggtttcg gaggatggcg gtctgcgcgt ctggccatgg caaggagcaa ttgtcgcgca
    40741 ttctggaagt cgcctcgcca gagcaatgcg gtgccctcgc aggccaagcg atgggccgca
    40801 tcggcagtca tgcggtcgtc ggcgatcacc acacgtttcg ggggaggcgc gccccattcc
    40861 gagcgccaat gcgcggcgta tgactgtcct tcttctgtcc acgttacctg tgccggttca
    40921 gtcatgcctg gctccgcgcg ctattgacgg aaataccccc tgctgacgcc tgtgtgtctg
    40981 cgccgacgca ccgaacggtc tcattgtgac agagtgaggc gttcggatca tgcggcagaa
    41041 aaatgtcgcc gcaccaagac ctcgacggat ttgaagtggc gctcgggcag gtttttgaaa
    41101 cgccgcttgc agtcgagcag ggcgtcgtcc acgtttgtga acggagcgat ggtctccatg
    41161 aggtggccat agtagtccat caatttcagc tcgactgtcc gcaggagaga cgggtcgccc
    41221 gccaatgagg ctgcggcttt ggcctggtct ccgctggcat ccacgagcgc ttgaaagcag
    41281 agccctttga gtcgttgggt caccgtgctg cgatcccatc cgagagcctt tgccgtcgct
    41341 tgcatgtcga agcgctgttg acgcaattgt tgtaagacgg cgaggtcgcc cgcaggattg
    41401 ggcaacagcg gcgcggcacc ggatgtgccg gttctcggtg acgctggccc ggacaggcgg
    41461 agatccgccg cggagagaat cggactgtcc gagagcgcca tggcctgctc caggcactgc
    41521 cgcaattccc gcacgttgcc cggccaggat tgttgcatga gcgtcgagac tgcctcttcc
    41581 gaaaggcgca tcgatgattg gtggttgtgg ttcgcagctt cgtggagata ggcctctgca
    41641 atgaggggga tatcgtcccg acgctcccgc aggggtggca ggtccagcac gaggcctttg
    41701 agtcggaaat acaagtcttc acgaaaccag ccttccgaaa cgccacgctg gagatccttg
    41761 ttcgtcgccg cgacaatgcg aacgtccact gtggtggggg ttgtggcgcc gactcgatag
    41821 aaggagcgat cctggagcac gcgcagcagt ttgctttgat ggtccagccg caggtcgccg
    41881 atttcatcga gaaaaatcgt cccgagatgc gccagttcga aatagccttt ccggtccgcg
    41941 tgcgcgccgg taaaactgcc gcggacatgc ccgaagagtt cactctcaaa cagttccggt
    42001 gagatggccg ccatgttgac ggcaatgaat ggcttcgccg ctcgtggact caaacggtgg
    42061 atcgcgcggg cgcagagttc tttgccggtt cccgcctcgc ctgtgatcag gacggtcacg
    42121 gtcgtgcgtg cgcctttctt caggtcgcga aacatcgtga ggatcgccgg attcctggtg
    42181 atcattcctg cctgctcaca ttcccggcga agggcgtcct gttccacgtt gcccagcggc
    42241 tctgccgtga tcgtcgcagc ccgcatgccc tgcagctgtt gttctagcgc cgccatccgt
    42301 tgccgcgtcg catcttcctg ggcctgggcc tcggcaatct tcagttggag ctccgccgcg
    42361 agcctgctcg attcggcttc cttggagact gaatgagaca tgctggcgcg agcggattct
    42421 aaatcctctt ccagactttc cacggccgtt tcccggtaga tcagggcttc ccggacggcc
    42481 acgaggttct gttgaaccag cagcatgtcc tgttccaaca gcaccaggcg tctggtcgcc
    42541 atcatctggc ccaggaggct gccgacgacg agaatcatga cgctggtggt gacaggaatg
    42601 atgaacggca agacccaatg ggcggtcgcc agcattgccc aactgacgaa gaaatagagc
    42661 accagcatgc tcgcgcccag aaccgggcct ttccaatccg tccagcgcag gactccccag
    42721 gcggtggaga ggccaagtgc gaatgtgacg atggcccgtt ggagcgggga aaggtcccga
    42781 atccagtctt gcgtcagcag cgtgtgcagc agatgggctt gcagcagcat atccggtgcc
    42841 tcttcgccgg tcggcatcat gcgttccggt tgaggagtcg gttgagtgag gaacagcacg
    42901 gctttgccgt tgaccagggc gctgaggccc tcattctcct tccggtcgat catgcgggtg
    42961 agatccaaca cagagagggt agggaagacc gtgggaagcg gatgtccggc aacgttgatg
    43021 agtagccggc cgtagcggtc aaccgggatg tcgatatcgc ctgtcgatcc acccgcaact
    43081 cgcgcgttgt gcagatgtat tcgccccgat cgtctttcga gttgattcga ttggacttgc
    43141 cagaaggtcg tggccaatga gaatcccaag gccggaagtt caccggggcc gtcgccatga
    43201 tacagcggca accggcggac cacgcgatcg gggtcaaacg tcgggtgcag ggcgcttctt
    43261 cccggtgtga agtgggagga cagagccgcc gcctcctgat ctgagacagc caccccgatc
    43321 gctgggtacg agacggtgcc ggcagatttc accgcttcca tcagcagggc gtcactgacg
    43381 gcgcctccga gattgggcgg gctgggaagc tcgagaggaa tatccaggcc gatcgaggcg
    43441 gcgccggcat catgcagggc ggtaatgagt cttgcgggga gcgcccgatc ccacgaaccg
    43501 gtgccgaact gttgatcgct ggctcggtct ctgacgatca ggagcaggtt cgggtcgggc
    43561 gccgcttgga cacgaaggcg catccaggtg tcatagggtg cccattccaa cgcctggcgc
    43621 gtggccgggg ccggcgtcca taggatgtcg ctgaggacga tcgcggccag cgtcatcacc
    43681 gcggcttgca gccagatatt cctgacgaac aggcgggtgg cgattcgcat ggggtgtcac
    43741 ggacgaaccg atactgaaat tgtctgctcg ttacggcttg ggaggttcag cggcgacgtc
    43801 gtcgaggata cgtttgacgt catccttcgg caaacccttc agatagctct tggccttggc
    43861 ctgatcggga gccagaccga gcccttttcc ataaatacgg gccagtgcca ggcgggaagg
    43921 aacggctcca tcggcggcag tggattccag gtaactcaaa atccattggc catgcggcgg
    43981 gagttggccg tcgagtccct gttcgtacag ttgcaccagc gtggcatggg ccatctcgtt
    44041 gagggcatag gcttcgcgca gcaggaccgg gagggcttcg gcggtgcggc cctgcttcag
    44101 caacgtcgtg ccgacggtct ccgtgggttg gtcgcggtcg aggtccggga agtccagcca
    44161 gatttgatcg caatagttct tgaacgcctc ggcggccgct ttggactgtt tggtctgcag
    44221 gttgcctttg accgctgcca gtcgccggag ttgtgtcagt gcctgcgctg cttccggtag
    44281 cccctgttcg aacgcctgtg cccaccaggt gatggccatg atctggcttt tctcgacacc
    44341 ctgtcccgag cgataggcat tgccgagaaa gtattgggct ttggacagcc cggccagcgc
    44401 agccgcttca agttcctgcg ccgcgtcttt gtctttcccc gcaactttga gtacgaggcc
    44461 caggcgataa tgggcttcgg caaaatcagg cttcaaccgc agcgcttcct ggtaggcctt
    44521 gatggccgac tggatgttgc cgcgtgtgta ttggatcgtg cccatgctgt agtgcgcctg
    44581 aacgagcgtc ggatcaaggc ggacggcctc ctgcaattcc gtcatggcgg ttcgccagtc
    44641 ctgcttggcc atgagcgcgg tgccgagatc gagatgcgcc tgcgcgaccg tgggatggaa
    44701 gcgcagcgcg gtccggtatt catcgatcgc gccatccgta tcacccagtt ggaagagcgt
    44761 tctcccgagg gtgagccggg gctcctgagc atccggttcg atatgcagcg cttgccgggc
    44821 cctggccaga atttcgagtg gtgtcagagg aggctgaacc ggcggcgcga ccggtggagg
    44881 tggcggtggc gcgggaggtt cgctgggaag cggttccacg cggatcgctt cttgaggggc
    44941 ctggtcagcc tgcggagcag cgggtgtttc ggtgacgggt gtttctgctt ggacggttcc
    45001 tgttgccgcg gcgggagaag gctcttcttg ggcaccggcc ggcagagacg gaagaggcaa
    45061 tgccactgtc gctatgagaa accaccgtcc gacggagacg cgttgcaaga acataggtgc
    45121 tggcagggct ccacgcaaaa ggtatccgac tatatacaca tagatgacgg gaaatttcca
    45181 tgggatctcg cggggaaccg tgcccatgac ccgccgggac cggatcgggg tgaaaccagt
    45241 ccgatgtacg aagtggatca atcggaacca cgctcacgtc gtcaggaagg ccagcgtcag
    45301 cgcaatggca gccaggagcg tgagcactcc taagaggagg tagcgccacc aagccaattg
    45361 atccaggacc ggcatgaatc ccaggctcac gccttcggcg agcatccagt ttcgaaactc
    45421 ctgaggcgcg acgacatgga ttccccgtgc ggtacaggac gcgatgaagc gatcgaccac
    45481 cagaccccgc actcccgcgc gaatcaaccg ttcaagccac tgcggtagcc gcagccgccg
    45541 cccggcttgc gcgaccgagt ggtcgacgag ggtttcgtat tcctgccgaa ccgtggacac
    45601 gtctcggccg gtggtgtctg cgctccggtt cagggcaggc aacgtatgga gccagtcacg
    45661 gaggacttgt tccaggcgtt ccaccatctg ccgggatgcg tccaatacgc cggccacagt
    45721 cccgcccacg agcccgatga ggatatacag agccgtcagg gaccagcttc cgagcatggt
    45781 ccaggttcca cggttcgaga cggagagact gtaaaagagt gccgcccctc ccacgatgct
    45841 ggtcgtgatc agtacgtgca gaggcagagt gcggatcaac gtctggaaga aggtgcgggg
    45901 actacttccg ttcggccctg gcggaatctg catcatgacc ggaggtcgtt taggcactgg
    45961 atggcggctg atgccggtga gccggccaga ttgcccggag gcgggccacc agggacttga
    46021 gggcatccgg ttcgggccgg actggttcat gcgcgatgcg ccacaccggc tcgagcggag
    46081 ccgggtcctg cgacaggcgg ggaatcaggt gccaatggat gtgcggaagc tggttgccga
    46141 gcagctcgta gttgatcttc accgcccgcc attcttcggc aaggagggcg gatacctgag
    46201 cgacttcttc gatgaggctg ctgcgttcct ctcgtgagag atggaacagt tcggtcgcgt
    46261 ggcgcttgaa gacgagcaca gtccagccgg gaaagaattg gtcgtcgtgg agataggcct
    46321 tcgtgaggcc gcaatcggcg atgaaatgat tctggctcgg ccaggtcccg acacaagcct
    46381 tgcaagcatg atcgctcatg gttggagaag ggtccgtgcc tcttccgccg tgatcaaccc
    46441 ctttttgagc aggagctgaa tgagtttgtc cgtggtcgct ttatgcggtg cggcggcggc
    46501 cgcggcagct gctgcttgag atttctgttt cggcggctcg cgtcgctggc ccatgacacg
    46561 gaatgaaggg gtgaacacgg ctacgtagtc ccggttccgg atacggacgg tgacggggag
    46621 gctttcactg ttcggggtga gatcagggcc cgatccttgc ggaatgcgga aatagggttt
    46681 tccatcctct gtggtcccgt cctgcccgat gatttccatc ctcgtcaaaa gggattcgcc
    46741 cgtcaggttc tcacgatcct gtccggcggt attggtgata tggtccagga ccaggatgag
    46801 actgtcagcc acaaagagat cgggtgaact gttgcgcacc gtcacgtcgt agcgatattc
    46861 gctggaaaaa ttgtcgcggc tgcgcagcgt gacgaacggc gtgaccttgc cggtcacatc
    46921 caccagttga tcggacgcac ccacgggagc ggcggtgtcc gccagcagaa ggcacgcacc
    46981 ggctgccagg atctgcatgg accgaggtat tctcatggtt ccctcccgtg gtcgatcgac
    47041 atccgattca gaataacaaa gccccgcagc cagtgcgagg aaatcctgtc ctgcgcgacg
    47101 gtctgcttga cacgttcttt tcatggacga tattctgccg ggcggtcaat cgtcgccccc
    47161 ggtgcatcac tcctgcatgg cacgtacacg tactacctcc cttcccttgc tggtgccgcg
    47221 ggcattcgcc tctacgctgc tacgatttta cgactatccc gatccgcgtc gtcccgggcg
    47281 aatgatcaag gggtatgact gccctcatgc tgtacggacg gcccggatgt gcgcggcggt
    47341 ggcccagcgg ttgggccacg caccggcgcg ggtgaagcag tatcagatcg cctgtctcct
    47401 tcatgactta ggccgtgccg gactcgatcg gacactcttc ggccgcatct ggtcctgggc
    47461 ccgcgcccat gggattccta ccaggccgcg cgaatggagg gcggcccatc ctgacacacg
    47521 ctacggcaag gagaccgaag cctttgtcgc ccgctatcga acggcgatgg agacagccgg
    47581 catcaccctc gatccatggg cttgcgaaca ggtggagatg cgtctggggt atgcacgccg
    47641 tctggccggg agactccgta tcgtaaaacc ggaattgcgt gacctgggag tggcctgggc
    47701 gccgtggatg gggcggatca tgctctatta ttactaccct gaaaagctcg ccggtgcgca
    47761 gccttgggtt cggcagctgg ccgagatcct cgtcgcgtgc gaacagttcg aagcgttcag
    47821 caatcagcgc cgtggtcgtg actattatgt gcgtcgccga gaagatctgg ccgaagcgtt
    47881 cgcctacctg aacggtctgc agaaagaagg catcatcagt cgtccggttg ttcaggcctt
    47941 gcgagagttg tcggcggaag gcgtgtttga tgctgtgctc gaacaggcga ggggccgggc
    48001 tttatcaaag agagaacggg catttttacg ccaggctagt aaggagtagc ggatggccgt
    48061 caaaacggta acgattcgag tgcccatgca gggcgacagc cggatggaaa atatcacagc
    48121 ccaggtccag gcggcgcttg agcaaacgcc actgcgggcc ggcatcgtga cggtattcat
    48181 caagcatacg accgcctccg tgctgatcgt cgaagatgag cccggcattc gtgccgatac
    48241 ccaggttctc tgggagcgcc ttattcccgc cgatcctcgc tggcagcaca atgagcgcaa
    48301 tgcgggcgag gataatgggc atagccatct gcgcggacag ctgcagggcc agtccctcac
    48361 gattcccttc acagacggag ccatgatgtt gggcatgtgg caacagatcg tggtgctgga
    48421 ttttgatacg cgcgcacgaa ccagagagtt ggtgcttcag atcatcggtg aatagatgcg
    48481 agcggtgaaa gtgcgcacac acatgtctgt cgcatgggcc tgtggagtgg ggctgttgtc
    48541 gagcgtgcta tcggggctgt tttccccggc cggtggtatc gcagccgaag caacatcccc
    48601 ttcgctcacg gcgcaggttg cggccccgac tgatctgagt ccggaggaac aggcgacgat
    48661 cgccgtgttc gatcgggcta ccagatcggt ggtgtttatc gccaatacgg caatgcagcg
    48721 tgatccctgg tcattcaatc tgttcgaggt gccgcaaggg tccgggaccg gatttgtctg
    48781 gagccggcaa gggcacatcg tgaccaacta ccacgtgatt tacggggcgg attccatcac
    48841 ggtgacactg gcggaccgga ccgaatataa ggcgaaggtc atcggtgccg atccggatca
    48901 tgatgtcgcg gtgctgcaga tccaggcgtc cgaggctaca ctccagccgg tcaccatcgg
    48961 caactctcag tctctgcggg tgggccaaaa ggtgctggcg atcgggaatc cctttggcct
    49021 cgatcacacc ttgacgaccg gtgtggtcag cgcgttgggc cgcaccatca aatcaatgag
    49081 caaccggacc attgagggcg tgattcagac cgatgccgcg atcaaccccg gcaactccgg
    49141 tgggcccttg ctggacagcg gcgggcgctt gattggtgtg aacacgcaga tcgtgagccc
    49201 cagcggagcg tttgccggga tcgggtttgc agtgccggtc gatacgatca accgcatcgt
    49261 tccggaattg atcaagcatg gaaagttgat caggccggga ttgggcattt cgctggtgcc
    49321 tgatgccatg gcgcggcggt ggggtgtcaa aggcgtcatc atcggcaagg tcgggcgcgg
    49381 cagtgcggcg gagcgcatcg gacttcatgg ggcgcgggaa accgccggcg gccgcattga
    49441 attaggcgat attattgtgg ccgtggatgg caaaccggtg gaaagcatcg atgacctgat
    49501 ggattccatg gaacaacata aggtcggtga tcaggtcacg atcgaattcg cgcgcggcaa
    49561 tcgccggatg caggcgacgg cgactctcca accagtcaat tgagtggagt cagagccacc
    49621 agaacgccgc tggcggccct tctcgacaac ctgttaggat gaccggagtg agattatccg
    49681 gaggaatgat atgagtgacc atcggaatgc ggatcaacct ggccatgggg gacagccatc
    49741 gccatcgcgc gatgcctcca cgcctgccga tcccatcgaa ctgatagatg aatgtctggc
    49801 ggcctttccc gacggcgacc ctcgtcagaa gctgctttat aaattgcgcc atgtcgtgac
    49861 ggcgcagtcg gtggcgcagg atcggcggga taccgaattg aagaagctca atgaggtcgt
    49921 cgcgaagctc acggcgccgg ccaaccgtgt gggcctgctc gtggaggttc cggctgaggg
    49981 cgtggcgcgt atcgtggttg gcggggcgga gtattatgcc aatatcgacc cgcggctggc
    50041 ggcagaggag ctcaagatcg gagctcagat tctggtcaac gaggcgtata cggtgatcaa
    50101 ggccctggag tatgaccgca atgggcccgt gttgaaggtt gcggagatct tgcctgacgg
    50161 acgtatccgg tttgagcagg atatgggacg gcaggccctg attcttcagc ggtccagcga
    50221 cttgctgggc gtggacctca aggccggtga tgaagtccgc atcgaaccca cacaccggat
    50281 tgccattgaa aagtttgaaa atcggcaggc gcggacccac ctgcttgacg aagtgccgaa
    50341 tgtcacgtgg gagcagatcg gcgggcagca tcaggccatt gatgccatcc gtaaggcgat
    50401 cgagtatccg ctgctccatg ccgacacctt cacgaagtac caatttacgc agccgaaagg
    50461 gtttctgctg tacggtcccc ccggttgcgg caagaccatg atcgggcagg cggcggcggc
    50521 cagtttgtcg cagctggtgc gcgagtcgca cgggcaggct gcttcagacg gccacacgaa
    50581 aaatccgccg gtgacgagcg gcgcgttcct ccatatcaag ggaccggaaa ttctcaacat
    50641 gtggttgggc gagtccgagc gcatcgttcg ggatctcttc gccaaggcgc gggccagacg
    50701 caaggaaggg gcgctgccgt ttatttttat cgacgaagcg gagtcggtgt tggggaccag
    50761 acggtcgatg cggtcattca acatcaacaa tacgctggtg ccgatgttct gcgcggagat
    50821 ggacgggatc gagtcgttgc aggatgtggt gatcattctg gcctccaacc ggccggattt
    50881 gatcgatccc gcggtgctgc ggccgggccg gatcgatcgc aagatcaaag tggcgcgtcc
    50941 gactcgagag gccgctgtgg agattttgtc cgtgtatctc acacccgcgc ttccgctcga
    51001 gcccgcgttg ctggagcaac acgatcactc tcacgacgcg gcgcgccgcg cggtgatcga
    51061 gcaagtggtc gacagtctct tctcgcgaac cgatcagaac cgtgtcctgt ccatacgtct
    51121 gcgcaacggg cagaacaagg tgctgtatcg cggggatctt gtcagcgggg ccattctgtc
    51181 tgcaatcgtc cagcgggcga aggaaaaggc gatcgagcgg gcagtggcgc agaccggcgc
    51241 ggcagcgggc gacggcattc gggcgcagga tctccttgat gccgtgcagg aggaatatcg
    51301 agaaggggaa atgctgcccc ccgacgatgc ggcggaagaa tggttgaagc tcctggacca
    51361 tcatccagag caggtggtgg gcgtgtcttc gttccgccgg ggcaggccga cggaagaacg
    51421 tttggtcaat cagattattt gatcggcggg aacgcggttc ttctcacgcg taacggacta
    51481 tgcatctctt cggcattgaa acagagtacg gcatcaccag ggaggatctc gacgcggtcg
    51541 atccggtcga ggaatccatg gagctggtgc gggcccatct gaccggcgag ttcgaacggc
    51601 ggtgggatta ccatggcgaa gatccgcatg aggatgcgcg cggcttccgt gtctcgggtc
    51661 tgcagcagga caaggaagaa gacgacttcg ccaaggtcga tgcccatcgt ccgtattcgt
    51721 tccatgagat gaagagcgat ttggtcttgc cgaacggcgc gcggttttac aacgaccaca
    51781 cgcacccgga gtattcgacc cctgaatgcc ggacgctcaa agatctcctg gcgcatgacc
    51841 gggcggggga gcgcattgtg caacgcgcgg cagatcgtcg caatcagcgg ttgggcgggg
    51901 cgcatgttca gctctacaaa aataataccg actttcacgg tcacagttat ggctgccacg
    51961 ataactacct cgttccacgg gcactgcctt tcccgcaatt ggtgcagggg ctcttgccgt
    52021 tcctggtcag ccgccaagtg atcgccggcg cagggaaggt gggtatggaa gcccaggagt
    52081 ccggctttgt gccgggcccc tttcaactct cgcaacgggc ggattttatg gaagcggagc
    52141 tgggtgtgga cacgatgcac aaccggccca ttctcaatac gcgcgacgag ccccatgcgg
    52201 accgggcaaa gtatcggcgg ctgcatttga ttgtcggtga cgccaacttc tgcgagtacg
    52261 ccacggcgct caaagtcggg accaccaggc tggtgctcga tctgctccag cggggcgcag
    52321 ctccgctggt agagttggag cagccggtga ccgccatcaa gcaattgtct cgcgatcccg
    52381 atctcaaaac gaccgtgcgg ttgaaggatg gacggacgat ctccggcctg gctattcagc
    52441 aagagtactg gaacgcagcg agccgggttt gcggggggag cgatcccgat gccgattggg
    52501 ttctccgtga atggcatgac actctgcagt gcctcggggg ggatcgcaca ccacttgtcg
    52561 gcaagctgga ttgggtcacg aaacagtggt tgctggaaac cttcatgcgc gaggagcagc
    52621 tcgcgtggga ggatccctgg ctcgccagcc tggatttgga ataccataat ctcaatcctg
    52681 accgtggctt gtttctcggc ctcgaagccg aagggaagac ctggcggatg acgaccgagc
    52741 gcgacattgc ccaggcgctc gtggctggtc cctcagatac ccgtggagga ttgcgcggcc
    52801 tgtgtgtcag acggtttccc gaacaaatca cggggatgca gtgggagcgg gtgcagttcg
    52861 cgggcgggtt gcgcggtcgt acgctggaga tgggcgatct gttcgatccg gaggcggtgc
    52921 aggcttgtgc cgggttattc gaaaccgcgg cgtctcctgc tgatgccttg gctgcgtggg
    52981 caaaacgaaa ggatgcacaa tgatgcgata tacaatgatg ccggagcgcc gtgaagcccc
    53041 cggcgatccg atgccgaaac caacaggccc ttcggaagaa ggcggcggtc ctcggcggcc
    53101 ggataccggt tcgccggaca aggataatct gctgaagcgg atgcgaaaag tcgaccccaa
    53161 gcaggcagag cgctatcggc agcgcacggg acaataaacg tgatagtcat cgtgaaacgt
    53221 aacggttgcg ggtgtgtcta acgaggtagg caatggggat gcaaggggac ttttttcagc
    53281 tcttgaaaga gcagggttat cagttcggga atccgtccgc ggctgcggcg ggattggata
    53341 ttccgaacgc caccacgatt cttgcgctca agtatcgtga cggagtgctg gtggcgggtg
    53401 accgccgggc caccgccggc aacatggtga tgtatgaccg gaccgacaag gtattggaga
    53461 tcgatcgcca tagtgtcctg gcgattgccg gtgtgccggc cactgcctac gagatggttc
    53521 gtgtgctgga gcattcattc aagtattacc gtcgcacaca gctacaggag ctcagttttg
    53581 agggtaaact tcgcgccgtc tccaagttac tgaaagaaaa cgtgccggcg gcgttggctg
    53641 gaaccggagc ggtggtgccc gtttttgccg ggtttgatca tgagcaggaa gcggccaaga
    53701 tctacttcta cgacattctc ggggctgagt tcgaagcggt ggagtacgcc gtgtccggct
    53761 ccggctcgcc gacgatccgg ggcatccttc attatgtgaa cacctggggc cctcaaccgc
    53821 tcgcagccat gcctgaagag caggcgacgg tgcaagccct gcgattgctc tccagcgcgg
    53881 cggagttcga ttcggcgacc ggtggcgtga atcgtgagtt gaacctgtat ccggtggtga
    53941 agcttattac cgcggcaggg gtgcagacca ttccggacac tcatttgaaa cacttgtacg
    54001 agcgtgacgt cgtccgcgcg ctctagccta tcgatgttca cttgaaggct ggagacctcg
    54061 cgggtctaag atgatcagga taaaggtgac gtgttatgta tgaagaaccc tatcggtgga
    54121 tcgaggcggt cgggaatcgg cggcagtatc tcgatgaaca gtttgcgatg ggtgcgccgg
    54181 tcgtggcgtt ggcctacgcc gacggcatcg tgctgttgac cgtgagccga ggcacgccga
    54241 agctctatga gatttatgat cgcattgcgc tcggtggcat ggggcatccg gccgatctgg
    54301 agaaattacg gttctcgctc ttggaaatgg cccatgtcga aggcttcaat cgatcgccct
    54361 ccgatgtgac aggtgcgagg ctgatgaagt acggcctggc gccggccatc aagcaggcgt
    54421 ttgaagagat ttacaaggcg cccttcatcg ccaaaattct cttggccgaa ttgggcgtga
    54481 aaccggaacg ggatctgttt ctgaccatca actacgatgg caactttgag gaacggcggg
    54541 gctgggctgc gttgggtgcg acgtccgccg tgcaagttca aatgggtcgg tatatcgacg
    54601 cacagccggg gtttgcccag gcttcattgg cgcaggccgt agaaaccggt ctctgcgcgt
    54661 gggcggtggg atctctggcg caaacctcgt ccggtacatc ggatggcgac tcctctgttc
    54721 gcgacgcggc agaaaaaccg gacgctgaag ccttgcccga caaaacggcc ttgctggctc
    54781 atgtgcggca gaccgtggcc gaaaaatctc tggaatgcgt gctgctggaa cgcaatggcc
    54841 ctggttcgtc caaatatcgg acccttcgcc cggacgaatt aggccgcgtg ctgccgtcgg
    54901 cggttcgagc ctcacagtga tctcctcccg aggtaagacg gaacaaatgg gcttggcatc
    54961 gatcacgttc tggagcccgg tacccatagt tggctgaata tgctgaatcg tattttcggg
    55021 atcgaaacgg aatatggcct cctggtcaat caggatcggc ctgaccattc gccttcctgg
    55081 gtggcgcagc gcatccggga ccacattttt cacatcgccc gtcgcggcgt gctcgatctg
    55141 caccatcgtg ggcatgatga gccgccaggc aacggggggt ttctgacgaa cgccgggcgc
    55201 atctacatcg acatgggcca tttggagtat gcctcgcctg aatgcacgac ccttgcggat
    55261 ctcgtggcat cagatcgcgc cggagaccgg atcattcaac aggccgtgac tgctttggga
    55321 ctggacgaga cggtctcgct catcaagaac aatatcgacc acgaaaccga tgcgacgttc
    55381 gggtcgcatg aaaactattt agtcactcgc cagttcccct tttctcggcg cggtcttggt
    55441 ccgctggtga ctttcttggt cacccgtcaa gtgtttaccg gcgcggggcg gatcggttgc
    55501 gccggtgatc ctaatgaatg ggtgcaaatc ggcgggctca tcttgcatcg tccggggttg
    55561 cgggacgcgc aggatcgatc gattgtcccg tttcagatct cccagcgggc cgattatatc
    55621 gtgaacgatt tctttgaatg ggtgcagcac aatcgggcca tcgtcaatac gcgcgatgag
    55681 ccgctggcgg atcccaatca ataccgccgc atccacttgc tctgcggcga ttcgaatatg
    55741 gcggaatatg ccaccgcact gaagatgggc acgacagggt tggtcctgca actgatcgag
    55801 gcaggccagg ctccccgtgg attgagtatc agcgagccgg ttgaggcgtt gcaggacatt
    55861 tcgcgggacc cggatcgcca gtggattgtc cggctggaat ccgggcagtc gatctctgcg
    55921 ctcgatattc aagaacagtt tcttgccgcc gcgcagcgac attgcaaagg ccaggacgaa
    55981 gagacggatt gggtgctgga gcaatgggag tcggtgttga ccgacctgcg gcacgggtat
    56041 gaaaaactgg tgggccggat cgactgggcc tcaaaactct ggctattgga aacctaccgg
    56101 gaggcggaac agttggcgtg ggacgacccg atgctgaaga gcctcgatct ggaatatcac
    56161 aacctgcatc ccgagcgggg actctgctac ggccttgaag aggaggggcg gggaccacgc
    56221 ctcacgacag acaagggcgt ccaattagcg caggaccacc cgccccgcaa tacgcgggcc
    56281 ttcggccgag gtgaattggt gcggcatctg ctggcgtcca cggcgagtgg ggcgggggca
    56341 gatgcggcgc atagttttgg tgaccatgcc tcctgtgaat acattatcaa ctggtccaat
    56401 tttaaattgc gtgataccga gccgtttttt atggccgacc cgttcaaaac ctacgtgcag
    56461 gacgtgcgaa gccatctcag tgcacgctag ttccggccta ccgcttccat cccactcgct
    56521 ccatcgcacc tttggacaca tcgaacgcaa agcgcaactg caccgcaaag tacttttgaa
    56581 ccagccctga ttgatccagc ggccgatctt cctcgcgata gaaggccagt tccatgtcct
    56641 gccagcgcac ggcaataccg acgatccagt cgagctcgga ggggttcagg gtctgactcg
    56701 cttcgcggtc ggtgaagagg tttacgtcgc catacagcac gaccttgttc ttatagacat
    56761 ccaggtcggc atgggcgaca taccggaaca aggcgcggcc ggtattattg ggtctggcga
    56821 agtactggct gttatgaaag agccacccag ctccggcata cgcggtgaaa ttctgatgag
    56881 gaaaggtgcg ccgccaccag gtggaatcct gaatggcctg aaatcgtgcc gtcacgagcg
    56941 cgtcggcata ggcttgcttc aagccacggc ggtcgagggg cgcatcgcgt tcatactgta
    57001 accgccaatt gaatcggtcc agcacaccgg tgaatgcgaa ggtgccgtcc cactcagaaa
    57061 gtttgatcca cccgtcggtg cgatccgaga aaaagttctg atcggtataa aaggtaaggt
    57121 attgcttata gaggtctgtc tccagatgca gcatgtgtcg catgccgacg agaccggtat
    57181 tgtcagggcg ggcggcaaag gtcggattct tcacaaacgc ccccgtcagg aagtatccgc
    57241 cgaacagggt ttcctcctcc tcccgtgctt cgtgttctgg ttcatccatg gagggaagtg
    57301 gccggccgta tttttcgaga ccgtaggcag gagggggcca gtcagcgaca gattgcaggc
    57361 accaggccat cagcagcagg cccaggatct tgcgaccgtt gaagcgccgg gtcttcattc
    57421 ctggcaattc gcaaagattt cttcacaatc attggaggca tcaacagaac tgggcacgaa
    57481 atggtatcgg acccgatcga cccgctgatc tttgaggatc acggtcgccc agcagccatg
    57541 atggacggtt ggccggcttc ccttcgatga caccatggat tcctcgagga ggggggcctc
    57601 ccggtaatag cggagcatgg tgaccggccc gtcttcacgc ttctgtaacg gattcccggc
    57661 gcaggccagt acttcttgaa gggtttttgc ctgaagtgct tgctggtgag ggtacccttc
    57721 tgtgacgggc gggctggttt gacaaccaag cacgaagccg gtcaggagga tgttcatcaa
    57781 gccaatgtag agccggacgt aggcagtctg catgatgagt gacagggcta gagagccagg
    57841 ccctgtgggt aacataactc tttgtttcaa agcaaccgaa cagccggcct ggactacgtg
    57901 gaccccgttg aatcccattc gctggaaaga ctgccagcag cgtaggcggc tgatgtccga
    57961 ggatgcggat cagctccctg gaaaaacggg ccttgtcgtt gtcagtgcaa gggagtggat
    58021 acggtaggtc tcggaattac gtatgccagg tatccgcgtc agtatcatga cggtcgtcag
    58081 tgctctgact ggtcctgtca gcgggttggg ggccgtaggc ggcgcgaccg gggatgggaa
    58141 gccctgcagc taacaactag gttatttctt gtaggccgcg ggatatcttt tctactgatg
    58201 agttgacaat tatgtctaat cacctagaat aagcttcgaa tctcagacag attggctagt
    58261 cgctgtgtgc ctacactgag gctgtgcgtg ccgcttatcc ttccccgttt tgatcatccg
    58321 acatcctccc gctgttttgg aatcgttcgt gcgcttgcaa gagtccagcc tcgcctcgac
    58381 gctcgatgca tgacggggcg agatggccac gggttactca ccacgatgct gtggcaggac
    58441 cgacaccagg actcaaacta gcgggaggaa atgtatgtcg tctgatagca ctgcgcgtaa
    58501 tgtgactcag ccgttatctg ccctctgcgg gcatgaggat agcctgaacg ttccggccgt
    58561 cgagagaaag aaaacgcagg acgcctggtc gctttctctc gccgaacggc gagcgtctcg
    58621 tcgtctggcg cttcgcctct ccactcagtt gttttttcag ggacacacct ggaagggggt
    58681 gaccaggagc ctcagtcttg gcggcctctc gatggacttt gtctccgaca ttcctgccat
    58741 gctgaatcag cggatgatgt tgagctttag cccggatgag cgcgggttgg acagcgttgg
    58801 tatcgtgtgc ggtattcgct cgtccgagga tgtgcacgta cctggtcgca ctcaagcggc
    58861 ggtgacactg gccatccagt tcatacacct gagtgacgca gatgaacggg ttgtggcatc
    58921 gctcctcagt catggcgcta ctgcgccaag acacatgcgt ctggcggccg ccttggtcgt
    58981 gcaggaagga gaggagtccc tcattgatac gggttcatta cagaccgccg ctacgcctcc
    59041 ggcctccatg caactggtac gagggccaga acgcccgagg gaagagcgac ggcgacagca
    59101 gcgggtggtt gttggattga gcacggaagt gagtcttcga actcgtggcg gggatcggcc
    59161 gttgtccgct ggcttgacga cggacttgtc gcccaatggc gcgtgcgtcc acctatcggc
    59221 tgaagaagat ctcttgggat cggagctcga attacgatgg ttgccatccg ctcccctcca
    59281 gggatcttcg accgattctt tgtcggcaac cctgtgctcg gtggtggggg aagtggtgtg
    59341 gaccagacca gttgcacccg aggctcgccc cgggtgcgtc cctgtggcag ggcgtaccgt
    59401 gctggcaggg gtgcgctttc tcccggttgc gaaggaagcg gaagatatca tcgaacattt
    59461 cctgggacag gtgtcgatgc caagccctga aacaaaagtg ggcagtccca ccgtgctcag
    59521 tgagttctca gaatgtttcc gaccatccgg cctccggatc gtcatctgcc atgaccggcc
    59581 acaagttgcc ccggcagctg acgccccgat tatcgtattg gcgccgggat atggggagag
    59641 caagcgcgat tatgtgccct tggcgtatta cctggcgggc aatgggttcc acgttgtccg
    59701 ttatgacaat gtgaatcatg tcggggaaag tgacggactg gtgacgcaat tccggctgga
    59761 ggacatggag gcggatctcg aaaccgtgtt ggaccatgtc gccaatcaat ggccgggacg
    59821 accgatcggc ctcgtggcga ccagtctggc gggacgcgtc gcgctgaagg tggccggcaa
    59881 ggtgtcgcat gtgcggctct tgaccctcat caacggaatt atggatgtcc ggcatacgct
    59941 gcaggccgtc catcaagagg atttgattgg agagcatctg tcaggtgtac acaaaggcgt
    60001 ggtgaacatc atggggctca ccatcgatgc ggatcgatgg ttggcgcatg cggtggaggg
    60061 cgagtatgcc gatctcctga cgacgcagcg ggatgcctcg cgtctccaaa ctccggtcgt
    60121 cctgtttcat gccgagcagg acgcctgggt cgatcccgct tctattgagc gggtgactga
    60181 ggcaatcggt ccgtatttgc gccactcctt cgttgtgccg ggcgcattac atcgcctgca
    60241 ggaaagtcca cggaaagccc gtaccgtgta ccggcaaatc gccgtctgtt gccaacagga
    60301 actctggccg gcgcggcggc cggagcgaat ggtcgaaccg tcccaccgtg aaatcggtgc
    60361 gcagaaccgg cttgagcgcg aacggagcaa gaagcggaag ccgatgggaa agtctgatca
    60421 cgtggcgttt tggcaggagt atttacagaa ctttcagacg attcccaatg tggccgattt
    60481 ctggcggctc atggatcatc tctatcgatt gatgggcgat tgccacaagg gcgagcgcat
    60541 tttggatgcc ggttgcggga acggcaattt cggggtcttc ctgcaattga atcaggcgtt
    60601 tcggcagcgg tatggcaagc gcggcgattt tcgctctccc gattacgtcg gtctcgactt
    60661 cgtgccggct gcattggctc aagccatgag caatttcgag caggtcggtg cgacgctgca
    60721 ggggcagttt tatgaagggc tgcgggccta tgagcccatg tcgatgcgtg tctgccaggc
    60781 tgacctggaa agcgcgctgc cgtttcccga tcactccttc gaccgcgtcg tctgcaacct
    60841 ggtgctgggc tacgtacgtg acccgctgtt cactttacgt gaatacctgc gcgtgctcac
    60901 tccacagggg cggttggtca tttccaattt gaaaccgtat gcggatcttt cggccattta
    60961 tcgcaatttt gtggatacgg ctcagacgaa ggatcaggtc gaggaaggtc gtcgcctgct
    61021 ggacaattct ggtagaatca aggaacgcga aggcgaaggc acgtttcatt tccactacca
    61081 gactgaactg gaaagtctac tgcgagccgc gggagtctca cgcccgcgag tgtattccac
    61141 gttcggcaat caagccctca ttgccgtggc cgaaaagggc atggcgcacg tcacggtcgc
    61201 tgcatgatga cacggctccg gtcctcccgg aggacttgat atgaaagtgc tcgcaatcag
    61261 cgcgctggtc aatgcgttgg ctgcgacagg gctcggaatg ttcgtctatt tccgggatcc
    61321 tgccgctgcg cgcaaccgga tctacgggct gtactgtctg agcatcgcgt tctggagcgt
    61381 gttttactgc gggtggcagc tggcggagtc gaaagatctc gcgctgagcc tgttgcgcct
    61441 ggtcatggcc ggcgcgtctc tcatccccat cctgtatttt caccacacag tcacgtttct
    61501 cgacattgcg gttcgccatg ccaaggcgct gaaaatcggg tatggactag ccggactgtt
    61561 cctgctggtc gatacgactc cctggttggt ggccggcgtg catccggcca tgtctttttc
    61621 cttctggccg gtaccgggcc cgttcttcca tccatttctc gcgtattttc tctggtacgt
    61681 ggtctatgcc acctcacttg tcggtgtcgc gcttcgcgat gccaacggga ttcgccgcca
    61741 tcaatatgcc tacatgctgg cagccagtgt cattggctat gccggcggcg cgacgaattt
    61801 cccgctctgg tacggggtgc cgctgttgcc ctatgggacg gtgctgatca cgatgtatac
    61861 ggcgttgatg gcgtatacga tcgttcggta tcgcctgatg aatatcagcg tcgtcctgaa
    61921 caaagggctg ggatatgcca tcgtactggc gattattgtg gtggcgacct ctatcggcgc
    61981 cgtcctcagc aatcgggcga ccggacactc cactcctcct ttattagccg gtactctgtt
    62041 tttgatctgt gccttatggg tgctcagcaa taatccccgc tcatcttcga atacggtgtt
    62101 tagcgccgta tgcggtgctg cgtgcctgtg gctattcggc tgcttcatgt tgttctctgc
    62161 cacccacgaa gaggaggccc tgttctgggt gcgagtcatt tatacgggag tcgtattttt
    62221 gcccgccctg acctatcact ttgcgcaacg gcttgcggga ggggcggtgc cggatcgggc
    62281 gattgggtgg aactacgccc tcggcgggct gttctggagt ctcttgttca cgacgtatgt
    62341 ggtggatgga cagtatgtct attattgggg ccggtatccg aaggccggcg tgctccaccc
    62401 ctggttggtc gcctatgtgg tgggaggcgg tgggctgacg gtgtatcggc tctaccaggg
    62461 ctatcggttc catcaaacat ccgctcctct tttaggcgcc caattaaaat ataccttcgt
    62521 ggcgctgtta ctcggcttct cggcctccct cgacttcttg cagaactatg gcatcgggtt
    62581 ctatccggtt ggctatttgc tggcgggact gtccgtcacg gtcgtcgcct acgccatcgc
    62641 gcgatacgaa ttgatggata tctcgttcgt gccgagcagg ccgaaggtca tgttatcgat
    62701 caagctggcg ggtctgattc cggcttacat gatgatattg ctggtgattc gaattttcac
    62761 cggcacgttc cactatctgc ttgccggagt gctcttcggg ctctttgtca ttgtgtcgag
    62821 tggtttggcc aatctgcaaa aaggcgtgga gcgtgcgatc gggcagaccc tctttcggga
    62881 gcgctatgat gcctacgaca cactcgtgca gttttccaag tccctggtgg cgatccttga
    62941 gctgaaatcg ctcacaaagg aaatcgtaca gacgctggcc cgcgtgatga acattaagac
    63001 tgcgtcagtg tatgtcctgg acaaagaaca gggggtgtac agtttgacag cctcctatgg
    63061 gtttgtgacg cgagatgtga tcgtccctcc catcaagatg gagagcgaat tcccgcgggc
    63121 cctgttgcgg accgaaaccg ctctggtccg agaagagatt gaatacgaca aagcggatgt
    63181 cgactaccta cgattgctgg atacattgaa ggggttggag tcggaagtgt gtatcccgtt
    63241 ggtcagcaag gagcggcttg tcggcttctg taatttaggg cgccgtgcca atcatggcat
    63301 gtattcgact gaagagttgg cgctactgaa aacgctggct caacatgcag ccatcgcgat
    63361 cgataacgcc ctgttgtatg aagacctgcg acggtcgcag ttgttgatgc gccgtaccga
    63421 ccgactccgg tcactggaga ccatggcggg cggatttgct catgaaattc ggaatccgct
    63481 gacctccatc aagacgttcg tgcaactggc tccagaccgg cgggatgatg tggaatttat
    63541 ggagcagttt agtcaggtgg tctgtgagga tgtcgagcgt attgaacgcc tggttcacga
    63601 gattctggac tatgcacggt atatgacgcc gaaattgacg caggagagct tgaacgacgt
    63661 cgtgtcctcc tgcttgtatt ttatcgaggt gaaggcgagc agcaaagcca tcactattca
    63721 aaaagaactc gcgccggact tgccctacgt caagctggat cgtcagcaga ttaaacaggt
    63781 gctgctcaat ttatttatca atgcgatgga agccatcggg ggcgaacagg gcggacgcct
    63841 gtctgtccgt acacgaaagc tcgtcaaatc tgtgaatgag ccgtgggtgc agatcgaggt
    63901 ggaggatagc ggcccgggca ttgagccgca cgatctggat catattttcg atccgtttta
    63961 taccaccaag catgaaagcg gcgagcgtga ggggacgggc ctggggttga ccattgctca
    64021 ccaaattgtc caggagcatg gcggctatgt ggaagtgttc agtgaggtgg ggcacggcac
    64081 caagtttatg gtaagccttc cggtaaaccc gcccatggcg gagtggcagg cggcacaacc
    64141 ggtttatgat gatggccgga aacttgccgg atcatttttg gccaggcctc atctcggttt
    64201 ggagcaacag ttcagcaagc cggactcacc cctcaaaacc cggacgtgag acaggaagtg
    64261 cacctgcctg agctgagcgt gctgtctcag gttccgcaca aatcattgga ggcctttgcg
    64321 gatggccgct aagacgattc tccgtctcaa ttatgcccga gaagaaagcc actcgataat
    64381 tctgttttcc gcccaaaacc gatcttctcc ataccggcgc ttctgaaaaa acccacagtg
    64441 tccaccgttc cgtagcatcg cgagcgtaat gtagcgattg tttttgatcc ccgggctgtc
    64501 gaacattgat gccggaataa agggatcgtc ctgggcggtg ataatcagcg tcggcaccgc
    64561 aatttcggat agcacgtggc gagcgccggc ccgattataa taatccgtag cgtctcgata
    64621 tcctccgtcg cgtgcggtgt acgtgtcatc gaattgagta atcgtcttca tgaggcgtag
    64681 aggcgagaga ttccattggc ctggaaacag agcggctttc cgttgcattc gggccttgag
    64741 actcgaaaga aagtgcgcat gatacagcca gtttctcggc tcttccagag cagccacaca
    64801 ttgcgtggga tcaatattgg gactgaccgc gaccacgcct gccagggccg cttccgatcg
    64861 ttgcagttct cccgctgctt ttagcaccag atttcccccc atcgagtacc ccacgagcca
    64921 gatatggctc aggccatcgc gctcccgcaa ttcccgtatg atggcaaggt aatcattgct
    64981 gagtccgctg ttatagagag ttggagtcag gtgatccgtg cccccacaag tgcgttggtt
    65041 catccggatg atgttgaatc ctgcgcagaa ggctttggcc gccatccctc gcatatagtg
    65101 agaatcggcc gatccttcaa ggccatgaac caggaggacg gttggtgcgg tcgtggggtc
    65161 atcctgccaa tgacaaaagc cgagaagctg ggtgcctggt tgagtcgtga agagacgttc
    65221 acagcaagga aggttctctt tccatctcag gcgaggccaa tatcgcggaa tcagcgtcat
    65281 caaatgcggg tttcggagca gcaatgcagg ggtaaatccg ttgaggatgg tcatacgtta
    65341 gtcatcatag ccaaaagtcg atctggttgc ccaaatcaaa ttttccttca gctgaaggtg
    65401 ctgcgtcctg cttaaggcct gaaagcaaaa tgccgataac agatgctgga tccttgtttc
    65461 ttacaggagg cagctatgct gacggcaatc ggcgatgtga tgaggcgggt gtacgagcgc
    65521 ggctggatca ccaccagaga tggcaacatc agcatgcgga agcgggatgg gaagtacctg
    65581 tatatcacac cgtctggatg gcggaagacc attgtgcatc ctgaacatgt ggtcaggctg
    65641 gaagttgtga cagatccaac cagcggtcat ttggtgccat ctgtacgaga ggggcagcag
    65701 ccttcgggcg aactttggat gcattggaat ttgcagcggg acaccaaaaa aacgcgcacg
    65761 gttgttcatg tgcacgcgac ccatatcgtt gccgccatgt atgcgggaat tgatttacag
    65821 gcgatgagcg ctgaattccc tgagatttcc cgctataccc gtgttggccg tacagttccc
    65881 gcattgcctg cgttatctcg tgacctggcc gatgtgacgg cggaatgttt agggctgaga
    65941 aaagacggga ccctggagtt tgacatcgta gggcaaaaga atcacggcgt gtgcgccgtc
    66001 gccacagatc cgtgggcggc ctatgagcac attgagcggc tcgatcacat ttgtgaaatc
    66061 gtgctgaaga gcggagttgc tgcacggtca tctggaaagc tatgacacgg tagaaagtct
    66121 aacgctcacg cttcagatag aataaggggc tgtcggcagc ataccgacag cccctttcta
    66181 tgtgtctaga ttggctccac ggactacatc caagtcggac gcttccattc gaaatgtctc
    66241 gcaatgattc tcgcctgacc gcgccatcat aataatggct taagacgatc taaggagcac
    66301 cttacatctg ccaatacaat tcggacactt ccagtgctct ttcgggaaat cgtgattgaa
    66361 gataacttct gagcttggga gtgatatttg ccgccaaaga tcgaacctct tcggctggag
    66421 gataatcacg cttgccatgt tgcgattcca ccgtcataaa gctaactgtt atgtcctttg
    66481 agtctatagt aatcaggcaa cgcacccatc cctcaaaccg cttgtcctgc aatcgatagt
    66541 cagatgtata tgtcgttcct gtgtggggaa ggagaccata tgactgtata cgctccttaa
    66601 gctcgaaatt tccgcttcgc attatcggat ctaactgctg cgacagggaa aatatttcat
    66661 ctgacgcatc gatgaaaggc cgaccaggat aatccacagt cgagcccatc tttaccttcg
    66721 ttacaggtcg ctgcccaagt atcatttctg cagtaacaca acctgtcagg aaaagtattg
    66781 ctactatgta gaggggaaag accttcattt taataacctg aaaaaatgcg gcccaatcca
    66841 tatacgacct ctctggcttg agtagaagca tgattctact ttgaccatat agatcaagtg
    66901 aagcgggggc tgcgcccccg atccccccgg ccgtccggtc cagtggtccg gaacggccgg
    66961 gcggcctcgt tgggtggagt tcctcttcga gtaatcccag tggttccgta agtgcttatc
    67021 ttgctcatct cacctttaaa agactttcca aggggacggc caagctgacg catcgccgtc
    67081 atcattgcat aactgtcgtc agataaggcc ctatcacccc ctggaagacg cagggcgtga
    67141 aagggctcat cggggtgcga ctgaatgata gggtgtttag tgtcgggatt tgcggaaggt
    67201 gaggccagcg caggcgcagc acagtaggat ttctctggca acgccgtaac tctggtaaca
    67261 gacacgtccc cacatcagat ccgcctgaca aaactcgcac aaacgttctt ggctgtgtgc
    67321 cgcgcagagc caaccctttc ggactcgatc atagactagg ccagggcgtc cgcagcagat
    67381 cgggccaaac aaggagtcga tttttcgaac gcaggtgtga gcggtcatgg tttcgaaaaa
    67441 gtcaggcctt tgcctaaaac cagttgcaga atgaatccgt caaaccagat tgcatgcccg
    67501 gcgagtaggt cctcccaggt tttaaagagt acgacgcgag ggatttcgat ttcccctcga
    67561 atgcgacgaa aggcattcct gctcgaccat tgattgcgca tttcttccca cagcgtactc
    67621 atggggaaac cgagggaccg tttccaggac cagcacatat ttacgtaacc tgattgatcc
    67681 tgaacgtatt ggctgatgac gtatcggctg aggcggttgc gggagcgatg ccccggtt
//
LOCUS       DAOQPD010000011        62715 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_162_length_62715_cov_21.653798, whole genome shotgun sequence.
ACCESSION   DAOQPD010000011 DAOQPD010000000
VERSION     DAOQPD010000011.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 62715)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 62715)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62715
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_162_length_62715_cov_21.653798"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            464..1495
                     /locus_tag="PK063_04330"
     CDS             464..1495
                     /locus_tag="PK063_04330"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96302.1"
                     /translation="MIPLRCLFCAICLCVTAYTADSAEAQVPPAQSSSVAQVDLKISE
                     WFSQGETVWSHNASGLDPNLGNPSSKLKYKDTGTNVTEITGRVQLKNKMFFRGAFGYG
                     AIGGGRLTDDDFLSAQGAASQGATVSGEHRFSRTYSDIGGDNLWYLNGDVGATAHTFQ
                     DNKGTLGVFVGLQYWRERHVATGVTQAECTTASAPSSEFRCSPAGTVGFRNQAVITNT
                     TTWFSGRLGGELEYKFDRRISVEAKVAMLLSYLDNEDVHHLRTDLAQDPSFRMTGLGI
                     GTTSDFNLRVKLWDRLYLTGGYRLWWNRVLVNDQWKLYGSDGSTASAPLTQFQTLRHG
                     PTVGLTYTF"
     assembly_gap    1527..1626
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<1627..2621)
                     /locus_tag="PK063_04335"
     CDS             complement(<1627..2621)
                     /locus_tag="PK063_04335"
                     /inference="COORDINATES: protein motif:HMM:NF012492.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HMZ96303.1"
                     /translation="MNTHELERLLMQQPVSLLHRLARGRISRHFRSGKRKLVDLLLQA
                     SAENRPGLESDLQTLIDERAQRPQPVPVEKTRPPEARSRQAVPATSRPHRTDDHGHHH
                     EPPVSLHEWLSGIGVPPPQPFVPDAWQVEALAKLAETDVVVSVPTGSGKTYVAIEATA
                     RAMRENRTVIYTSPLKALSNTKFTEFSRVFGPGQVGILTGDRREHSQAPLLIMTTEIL
                     RNLLYDAAGGEIDVRLDTLGLVIMDESQYLADPERGVVWEETLIFCPSQARLLLLSAS
                     IGNPQDIADWLTAIRPSPCSLIRHTKRSVPLRAGYLHPNEKLTPLFRTAGIPYGQP"
     gene            complement(2618..4480)
                     /locus_tag="PK063_04340"
     CDS             complement(2618..4480)
                     /locus_tag="PK063_04340"
                     /inference="COORDINATES: protein motif:HMM:NF019758.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-related protein"
                     /protein_id="HMZ96304.1"
                     /translation="MPPSIHPVDLVATLRQRNLTPAIIFLTSRRACDEAMQSFERSQV
                     TLPKAQQEQIARVLTQVTEQFPSIAEHPLIETVQRIGVAAHHAGHLPSWKIAVEELMR
                     TGSLDAVFATTTLAAGVDFPARTVVVTQSSIRKARDFTDLTASEIQQLAGRAGRRGKD
                     LVGFAVITPSPYIDLTVLTKGLTGQPEAIHSQFVISYPMVLNLLKAHPREQIQSILAK
                     SFAQFQLNQRTAVLETKLDSLRAEMEPFGPRVCSDWITQWQVFEQARKRKKPRSPFTR
                     QESPDVAARLHFLTPGRVVGVTRGRGIILRQYRSKGQHAPMVTLLREGGSLNECPASI
                     VTQVFDRTFDCEETSTYPWCTPQALEQLTHHLTDLPPRLPILPILAHQHEETPIDSSI
                     IQTLGDFPCPTCPSRQACQRDFPRASRVRQEIQRHIKSIQALQTSLWHRFQERIDVLE
                     KFGYLHANAQLTADGEWARLIRIDHSLLITELIRAEAFGAIDPPLLAAVMASIAHDDD
                     RPGSFPRGSAGLVTLLFQVRKLAESLTPHEAPPMLRADVAALTERWVSDQTLTWIGLA
                     RLTTMAEGDMFRLFARTIEFLSQLKTLKATHPSLAESADHAITAMRRGVLEELP"
     gene            complement(4455..5693)
                     /gene="glgC"
                     /locus_tag="PK063_04345"
     CDS             complement(4455..5693)
                     /gene="glgC"
                     /locus_tag="PK063_04345"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HMZ96305.1"
                     /translation="MANIFTMVLAGGKGERLQPLTDQRAKPAVPFGGKYRIIDFTLSN
                     CLNSGLRQIAVLIQYKSHSLDRHIRTGWNILNPELGEYIVSVPPQQRISEEWYRGTAD
                     AVYQNLFLMDNDHPEFLLVLAGDHIYKMNYADMYNLLIEKQADAIVGAIETPIADANR
                     FGVIAVDEDRRILSFDEKPEHPMHIPGDPTQAFVSMGIYLFRTDVVREQLIRDAKEGT
                     KHDFGKNIIPRMIKECRVYAFKFQDENKKAVNYWRDIGTLDAYWEANMDLVSVDPQFN
                     LYDQHWPIRTYQGQFPPAKFVFAQDFQGGRMGVALDSIVCGGCIISGGRVQNSVLSPH
                     VRVHDHADVRESVVMENVVIGEHARIRRAIIDKDVVIPPKTVIGFDPVADRQRFKVTD
                     SGLVVISKGMKLHAAVDPSG"
     gene            5828..6106
                     /locus_tag="PK063_04350"
     CDS             5828..6106
                     /locus_tag="PK063_04350"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96306.1"
                     /translation="MKKQNARPAIMKPAIEPANPMMEMVWRLERLERQVQRLSELVRN
                     HAEDNDRLVRIVAEDRDVIRRELLRKHEHRVRVRKHLRDVSSKVDLEH"
     gene            6230..7282
                     /locus_tag="PK063_04355"
     CDS             6230..7282
                     /locus_tag="PK063_04355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ96307.1"
                     /translation="MRHHGPVAAVDHVSFQVRRGEFFSILGPSGAGKTSVLRIVAGFE
                     DPDAGDVLIDGRSMLGVPPNRRPVNLVFQSYALFPHLTVFENVAFGLRMRRVPAALIA
                     EQVEQALAMVKLVGKERRKPAQLSGGEQQRVALARALVNKPAVVLLDEPLAALDQQLR
                     QAMQVELKSIQEQAGLTCVCVTHHQEEAMMMSDRIAVMHQGRMWQVGTPREVYENPRN
                     LFVSRFLGVSNELPGRVDDVVEDGHLFHPADDQVPAFPVRAGSEASPGHSATWSIRPE
                     RLRMSRERPAGRDAVLNGFIEKVLFAGSETKYLVRVGRDRLWEARTTGAGESPHAPGD
                     PVFLHWASGDGRVFVE"
     gene            7285..8175
                     /locus_tag="PK063_04360"
     CDS             7285..8175
                     /locus_tag="PK063_04360"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HMZ96308.1"
                     /translation="MPSDDVSHVSPASQDSCRSCWLAAPGLLWLALFFLVPLVLVFAI
                     SFASRGTYGGIVWEFTWANYVDLLHPLYGKILGQSLWYATLTTAICFLLGFPLAYVIA
                     RSPARWQPVLLLLVMLPFWTNFLVRTYAWMIMLRHDGLANNLLLGLGLITEPLELLYT
                     PTAVVIGLVYGYLPFMVLPLYVAVERLDPVLVEAAWDLYASRWAVVTRVVIPLTMPGI
                     VGGCILVFIPSIGSFITPDLLGGARSMMIGNLIQHEYLVVRDWPLGSAVSFVLMAIVM
                     AAVVLYYRQASPGDGPLEGR"
     gene            8172..8945
                     /locus_tag="PK063_04365"
     CDS             8172..8945
                     /locus_tag="PK063_04365"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HMZ96309.1"
                     /translation="MKQRSLGLNAVSLLAMLFLYGPIIVLVLYSFNAAHLSMTWRGGT
                     LKWYAALVHDEALLAATANSLLIALVSTIGATGLGGLLALGMEQMPHRRQQLLEGGLV
                     LPLVIPEVMMGVALMLLFVTVHVPLGLTTVILGHIVFNIPLVTIMIRTRLRKLDPMLR
                     EAAADLGADSWQVFRHVTLPLLRPAIWGAVLVAFTVSLDDFLVTFFTAGPGSTTLPLK
                     VYSMIKSGVTPEINALSALLLVVSMIGVAASLYLQRREV"
     gene            8991..10016
                     /locus_tag="PK063_04370"
     CDS             8991..10016
                     /locus_tag="PK063_04370"
                     /inference="COORDINATES: protein motif:HMM:NF024808.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0019808 - polyamine binding [Evidence
                     IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015846 - polyamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HMZ96310.1"
                     /translation="MWLTGYLTGCGQRFDENRVETRPVLHYFTWSDYVSPDIIQEFER
                     REQVKVVIDTFSSNEELLAKLQSGATGYDVAVPSDFMVAIMIQQGLLSELDQAALSNT
                     SQLEPHLQTLPFDPERRYSVPYLWGTVGIGYDSASIPTPPDSWSILWDARYKGRISML
                     NDQREVFGAVLRSMGQSMNSTEPQVIESAKDRLLNQKPLVKTYTSDHYDQLLASGEVV
                     LAHGWGGQVARAMADRPSIRYVVPKEGATIWADCLVVLRTAPQKALAMRFINYLMEPT
                     VAARTSERLRFASTSRSARELVDAATRDNPAVYPSLDQLARLEWMRDVGKGIRLYDRA
                     WTELKMQ"
     gene            10062..11459
                     /locus_tag="PK063_04375"
     CDS             10062..11459
                     /locus_tag="PK063_04375"
                     /inference="COORDINATES: protein motif:HMM:NF014385.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HMZ96311.1"
                     /translation="MRALSSVDRYSRTMRDDMSQHKNGSPSGVRLWHQHPGLWVLIAL
                     LGLTLFGSGWVRAAESTTIPAGSFAPPVVRLNLSEAVALFLKQNFDLLIAKYGIESSK
                     GQQITARLFPNPVAQIGTVASFTHGNTAANSGALTMQVQQLFELAGKRGYRIESAGFG
                     VQSAEADFEDAIRQLGFTLKDAYYRVLVAQRRLALAEENRDRFARILDVNTIRFKKGY
                     IAEVDLIRIRLQVVDFQSQVIESIQEGESARADLRQLLRLSPASKLELTTEMDYRRVD
                     PDMGKLRSVALDVRPDIRSRRALVAQREADLKLAKAFRVPDLTIGAGYSIQGPRGPDN
                     PQMGILNLGVPLPLFNRNQGGIVQAEVGVQSAQAELDRTVNQVENQVDVAYHNLLQSR
                     RLVEAYLAGVLEDARSTFTIVERAYERGGATILDLLDAARTSRTIQQNFIEALFSYQR
                     NLFQLESSVGQEITS"
     gene            11456..12604
                     /locus_tag="PK063_04380"
     CDS             11456..12604
                     /locus_tag="PK063_04380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HMZ96312.1"
                     /translation="MNSGAIPVIGLTVVLLFSACSQKQDSAPSPPSASSEPVVAPAVP
                     PSAGQIETAVVDFKPVQPELVLVGKIAYGEDRYSKISSPLQGRVVEVRAKLGDRVEAG
                     ATLLVIDSSDITAAYSEFVKEASELEYSTRAQELAKELYATKALALKDLKQAENDLIK
                     ARAEFRRAKERLLSLRIPAAELEKPLAQQRITSRFEMKSPLTGTVVERAVTPGQSVGG
                     DVGQVLFTVADLDRLQVVADVYERDLALVKVSQVGRINVEAYPGTDFASVVASIGDVV
                     DPNTRTIKVRAWVDNRDQRLKPEMFARLRLDIGDATPFLTIPKEAVVEIDGKHFVYVV
                     DGADHYSKHEVTVSNVSSGQVRILEGLTSGQRIVTKGAVLVKGQEVKG"
     gene            12654..15758
                     /locus_tag="PK063_04385"
     CDS             12654..15758
                     /locus_tag="PK063_04385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051139 - metal cation:proton antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CusA/CzcA family heavy metal efflux RND
                     transporter"
                     /protein_id="HMZ96313.1"
                     /translation="MMVRIVELSLVQRFLICALGFTLLFGGLYAFQQLDIVAYPDPSP
                     PMVEVITQFPGWSAEEIERQITIPIEVALNGMPGLTDIRSLSIFGLSDIKIYFDFNTQ
                     YFFDRQEVVNRLSTLSLPQNVQPALSPWWAIAEIYRYQLEGDGKASLTDLKTIQDWQL
                     RREFRRVPGIIDVTAFGGTTQEYHVDVDPGKLISYQVSLAQVMEALTNSNANVGGNYL
                     TVGAQNYNIRGLGLINGLADIENVMVAEKEGTPIFIKTLGSVSVGHRVRLGKVGIDDN
                     DDVVEGVILLQRGYKALSVLDRVREKVEELNKWKLPEGVKIKTFYDRTALIHTTVETV
                     TDILISGMVLVFIILFVFLGHLRASLIVALTIPMSLLFTFTMMVMIGQSANLISLGAI
                     DFGIIVDATLVMVESIFFHLGHDRRLGLTVPQQIVRAARQVGQPIFFSTAIIVVAFIP
                     LFTMTGVPGKIFAPMSITYGFALFGALLMAFTLAPVLCSLLLTGVVTEQDTRFVSAIR
                     RTYLAVLRWALAHNMKVIGAALLLLVAAFGALQFIGGEFMPALEEGNLWVRATMPVDI
                     SFDEAARLTGEIRQMFRKSPEVVTIVSQLGRPDDGTDPTSFFNAEFLANLKPHKDWRT
                     GLTKDQLVEEIEERLKVIPGIIFNFSQVIQDNVEEAMSGVKGENSIKLFGTDLKTMEA
                     KAGEIESVMRGVHGVKDLGIFRLVGQPNLLIQVDREASARYGLRVSDVNAVVQAAVGG
                     QAVTQVFEGERLFDLVVRFLPEFRRDEEAIGNILVNTPNGARIPLKQVATIKTQTGAF
                     IIYRENNERYIPIKFSVRERDLESTVKEAQAKMAQAVSLPERYRIEWAGQYDQLTAEQ
                     KRLTMIVPLSLVIILFLLYTTFNSLTNALLVLVTVPFALIGGIFSLVFTGTHFSISAA
                     VGVISTLGVAILGGVLLISRIEDFRRSGLELREAILKGADVQMRPILMATLAAAIGLL
                     PAALATGIGSQAQQPLARVVVGGMLTAAALILVVLPVLYEVVHRRTAPRTPLEAGEEP
                     PAPY"
     gene            15786..16589
                     /locus_tag="PK063_04390"
     CDS             15786..16589
                     /locus_tag="PK063_04390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HMZ96314.1"
                     /translation="MIGVGQQRMRQVVVLGLILLGLMGMRPEAGWAGSMVWPVQMPYE
                     APPKSEPVPDVSIAPNTKALTPEELQRAESLLPLLEGKQEFWAMGEFVHLGEPALPVL
                     TKALTMPGPRIRYNAIETMSMIKAPAATPALLEAAKLATEIPRIREHALRVAVRLDPQ
                     QAPPAIEAMAKDPNSVIRKAAAFEARYVRKKEVIQPLIDLLGDEEKFVAMSAVQSLWT
                     LTRHETEFHDWDASNKQDRQNWAQEWIEWWNQSKETFEIPDPKTRKQAG"
     gene            16700..17230
                     /gene="def"
                     /locus_tag="PK063_04395"
     CDS             16700..17230
                     /gene="def"
                     /locus_tag="PK063_04395"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HMZ96315.1"
                     /translation="MAILAISKLGNPILRQQAQSVSPSEIKKAAFQQLIDDMFETMYD
                     EPGIGLAAPQVGRSQQLVVMDCPGEGGFPKTVLINPTIRFYGPEQVEGWEGCLSVDGL
                     RGKVTRPSTVRVTGLDRNGKPFDFEASGLYAVCIQHELDHLIGKLFIDRMTDFSTLTQ
                     MDEFQKYWQKEPASVI"
     gene            17300..18979
                     /locus_tag="PK063_04400"
     CDS             17300..18979
                     /locus_tag="PK063_04400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ96316.1"
                     /translation="MLAVVTFVCAGLATALELVPPYLVKIVIDDVIQAKRPEMLMWVL
                     GALLGSYILRNLMSSMRVRFNNLLEQKAVHTLRMQVFGALQRLSLSYFENRSTGEIMT
                     RVTSDTEHVERIFVDGLEGLLTASLTLIGITIMMFFLNWKLALLSLVPIPILIVCAAW
                     FTKRVHKYYAEIRKSVADLNAYLQDALSGIKETIGFNQHEYERKRFETLSQTYSQNSL
                     RAMFLWSWYWPGMVFVGSTGTVLILWYGAEEVMAGNLTVGQLVMFLSYLGLFYTPINE
                     IHSLNHMLQHALAASERVFEILDTKAEVEDRPGAVRPVERLRGAVEYRQVVFGYRQEG
                     TVLSDVNLTVRPGERIALVGPSGAGKTSLLKLLMRFYDVRSGAVLVDGYDVRDLPVAF
                     LRGQIGLVQQEPFLFNGTVRQNIVYSDLSASHERVEAAARAARAHDFITRLPDGYDSW
                     IGERGVKLSVGQKQRVSIARVLLKDPPIIIFDEATSNIDTETEVKIREALNDLTKGRT
                     TFIIAHRLATLHDVDRIIVVERGTIVEEGHHDALMKRGGVYAGLYEAQFKI"
     gene            19162..19356
                     /locus_tag="PK063_04405"
     CDS             19162..19356
                     /locus_tag="PK063_04405"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96317.1"
                     /translation="MVLIFESDPLDNEDARGRFYHVCRGRIDRTEITLPQGQSIYECA
                     VCGIDLEPEDFWIARQKGSV"
     gene            19398..19607
                     /locus_tag="PK063_04410"
     CDS             19398..19607
                     /locus_tag="PK063_04410"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96318.1"
                     /translation="MAGSIGRKTVSVSRGLMMLCETCYDQVYAEKLPDARNFIADHEA
                     LFDTICMGCTDINRPLIDDMLGSSE"
     gene            19831..20235
                     /locus_tag="PK063_04415"
     CDS             19831..20235
                     /locus_tag="PK063_04415"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96319.1"
                     /translation="MKPLVAINGASMFGELAIVSCLEKDGWTAFWVDTFHGRKFWRGM
                     PHVTQPTEPPTKVKALYARIADRKGGPSGCFDIVASKGDRIIWLEYKGPKDTANRNEL
                     CWIEAALGAGVAESSLFFVGSDRRPKAVERTI"
     assembly_gap    20469..20568
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<20569..20829)
                     /locus_tag="PK063_04420"
     CDS             complement(<20569..20829)
                     /locus_tag="PK063_04420"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96320.1"
                     /translation="MRLLLVMIALILCLTGLTHPGTSSAAEKSYYSPIINVDVDNSRI
                     LISTLGAVFWVDVPEEAKAHIEKLPQSGLVDIVVETREGQPPL"
     gene            complement(20928..21440)
                     /locus_tag="PK063_04425"
     CDS             complement(20928..21440)
                     /locus_tag="PK063_04425"
                     /inference="COORDINATES: protein motif:HMM:NF025819.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M67 family metallopeptidase"
                     /protein_id="HMZ96321.1"
                     /translation="MPDLSIPQHILDQIVAHARELAPFECCGLLAGKNKVVTHLYRIT
                     NIVAVEGAEKLSTFDEDKVAHLERLSPEERAEIAFVMDMGDFSAAKKDIRKNGLDLQV
                     VYHSHPKDPARPSHTDIKIATDYEEIWQRINLPVPAYLLVSLMHAPAADIRTYWITGG
                     QVRPADIHIM"
     gene            complement(21442..22245)
                     /gene="moeB"
                     /locus_tag="PK063_04430"
     CDS             complement(21442..22245)
                     /gene="moeB"
                     /locus_tag="PK063_04430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-synthase adenylyltransferase MoeB"
                     /protein_id="HMZ96322.1"
                     /translation="MEFTDQQIQRYSRHIILNEVGGKGQVKLAKAKVLLIGAGGLGSP
                     AALYLAAAGIGTIGLVDGDVVDLSNLQRQILHTTATVGVPKVESGRRMLSAINPDITI
                     KTYQLNVDTENILGLVSDYDIVLDGSDNFTTRFLVNDGCFFAKKTLISASMFRFEGQL
                     TSIKPHAGFPCYRCLYPEPPPAGLVPNCQEAGVLGVLAGTMGILQASEAIKEILGIGE
                     TIADKLVIYDALEMKFRKVSRPKDPRCPLCSATPTIKDLGGDYSVACTI"
     gene            complement(22321..22560)
                     /locus_tag="PK063_04435"
     CDS             complement(22321..22560)
                     /locus_tag="PK063_04435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NIL domain-containing protein"
                     /protein_id="HMZ96323.1"
                     /translation="MTSLRFHIRFPENKIKEPIIYQIGHEFRVVTNVRRADVRETTGW
                     MDLELTGETEEIERAIDGIRTKGCVVDPIELNVVE"
     gene            complement(22563..22835)
                     /locus_tag="PK063_04440"
     CDS             complement(22563..22835)
                     /locus_tag="PK063_04440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014960632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoaD/ThiS family protein"
                     /protein_id="HMZ96324.1"
                     /translation="MIKVRIPTPLRPLTKGQGEVESAAANIVDMIGSLDATYPGLKNR
                     LCDEKGDLRRFVNIYVNEEDIRFLNGKETSLKDGDEVSIVPAIAGG"
     gene            complement(22832..24082)
                     /gene="thrC"
                     /locus_tag="PK063_04445"
     CDS             complement(22832..24082)
                     /gene="thrC"
                     /locus_tag="PK063_04445"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HMZ96325.1"
                     /translation="MSKMKALVCRECGKEYPPKAIHVCEMCFGPLEVKYNYDEIKSTI
                     SRKKIEQGPNSMWRYIDLLPVESTSIIGPHAGLTPLVRAKNLGAHLGIDELYIKNDTV
                     NHPTLSFKDRVVSVALTRARELGFETVACASTGNLANSVAAHAAAAGMKCYVFIPADL
                     EAAKVLGNLIYKPNVVEVEGNYDDVNRLCSEIAGEHGWAFVNINIRPYYAEGSKTLAF
                     ETVEQLGWRTPDQAVIPMASGSLLTKIWKGLHEMKALGLVDEVRTKINGAQAEGCSPI
                     ATAFKAGRDFFKPVKPKTIAKSLAIGNPADGYYALKATAESKGAMDAVTDEEVVEGIK
                     LLAQTEGIFAETAGGVTIGVLCKLVKQGLIKKNDVTVAYITGNGLKTQEAVVDAVGRP
                     FRIQPSLVNFQKTFKMGKNSGGES"
     gene            complement(24096..24923)
                     /gene="moeB"
                     /locus_tag="PK063_04450"
     CDS             complement(24096..24923)
                     /gene="moeB"
                     /locus_tag="PK063_04450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-synthase adenylyltransferase MoeB"
                     /protein_id="HMZ96326.1"
                     /translation="MEFTETQINRYSRHILLPEVGGKGQKKIIQGKVLIVGAGGLGSP
                     AALYLAAAGIGTIGLIDSDVVDLSNLQRQVIHQTPDVGRPKVVSGKEKIQALNPDVNV
                     VMYEERLTAGNALKIMSGYDVVIDGVDNFPTKFLINDACYFAGKPLVHGGILRFDGRV
                     TTIIPKKSACYRCVFKKPPPEGLVASCQEAGVIGVLAGIIGTIQATEALKLILGIGRP
                     LTDRLLDFDARRTQFREIRIKRNPDCPLCGERPTITELIEDGDVGGPTCALPGQRNL"
     gene            complement(25075..26004)
                     /gene="cysK"
                     /locus_tag="PK063_04455"
     CDS             complement(25075..26004)
                     /gene="cysK"
                     /locus_tag="PK063_04455"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HMZ96327.1"
                     /translation="MTAKAHGDITELIGGTPLVRLNRLTKPGSATIYAKVESFNPGGS
                     IKDRICLNMINEAERQGKLKPGGTIVEPTSGNTGIGLALVAAVRGYKLILVMPESMSM
                     ERASLLSSYGAQLVLTAAWEGMKGSIKEAESIVAQNPSYYMPDQFSNPANPAMHRKTT
                     GPEIVEALDGRVDAFVAAVGTGGTITGCGEVIRERNPAAKIVAVEPAGSPVLSGGDPG
                     PHKIQGIGAGFVPKVLNRTLLDRVITVTDDEAYQTAKLLAKKEGLLVGISAGANVFAA
                     QKIAEELGPGKNVVTILCDTGERYISIEKYFNI"
     gene            complement(26001..26201)
                     /gene="thiS"
                     /locus_tag="PK063_04460"
     CDS             complement(26001..26201)
                     /gene="thiS"
                     /locus_tag="PK063_04460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HMZ96328.1"
                     /translation="MQVMINGKAEEIAGGTVLDLLKAKSIEPQMVAVEVNDTMLERTH
                     LETTQLKDGDHVEFLFYMGGGR"
     gene            26593..26973
                     /locus_tag="PK063_04465"
     CDS             26593..26973
                     /locus_tag="PK063_04465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96329.1"
                     /translation="MWKKNFLFRAHEAAPLKESENELFHDDAEPALDSAGLQMEKFLS
                     VWVQGEGEDEKPTMYTNMYVRTATLDFKTRAGFLQPLQGRTHQIKQMLTPEQKGFLRE
                     WLSTTSPQAWEDSDDHFRTLFDLE"
     gene            27188..27733
                     /locus_tag="PK063_04470"
     CDS             27188..27733
                     /locus_tag="PK063_04470"
                     /inference="COORDINATES: protein motif:HMM:NF024491.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D-like domain-containing protein"
                     /protein_id="HMZ96330.1"
                     /translation="MSHPTSLPLMALIVAGFMFLSQGPVCASATIEVYYAPEDHPIDH
                     VVNLYGRATRYIYVSVYGLTAPSIVKALVEAKHRGVDVRVITDRERLTDPKQHSAVKT
                     LRLAGVPVRINRHDALMHLKQVVIDDEINTSGSANHTTSGNRYNDERLDVITDARLTA
                     RAREKFLAMWNDRERFVVWTE"
     gene            27742..29019
                     /locus_tag="PK063_04475"
     CDS             27742..29019
                     /locus_tag="PK063_04475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent monooxygenase"
                     /protein_id="HMZ96331.1"
                     /translation="MARASIETDVAIVGAGGGGAVLALMLAQQGVRSVVLERASGPPQ
                     GLRGEILQPNGQRVLDRLGLLDKLPAHAVRSVHRFNFCRSGGERLCTVDYSDLPAPYN
                     RAVVTLPNVAHHAILDALEKQNPGGLWYDATFTGLRFDGSRVVGLQATRHGEPVEVSS
                     RLVVGADGAFSKVRESLGISADIHRYPESYLIAILKAPTGFDEARYLVGKREILGLFP
                     AAGQQVYAFYMIKAGSYDAVKAQGLESLRRAWVRIDPAMESIVSGLVDWNQTGYMPTG
                     RVRTDRWVADGAVLIGDAAHAMNPHASQGRMQAMVDAVTVADLIPGWLKNNTFSSEAL
                     RAFEVARRPQVSMLQRLADEQCRFWNTGNPLLAFLRDRVFRTLDRNARLRYRVLTTTA
                     GLRSQPPFSMLDRVMAAGLLPDPSADRKSSVGT"
     gene            29222..29980
                     /locus_tag="PK063_04480"
     CDS             29222..29980
                     /locus_tag="PK063_04480"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96332.1"
                     /translation="MTQPTALDVPSEVQQLLQRYVKETTTLLGPQLEGILLYGSAVGG
                     EFLPGRSNLNLLLMLSGYDREGMKRYAKAHKRWSREQFVVPLLVTETELTKPGTVFPL
                     EYLEIQEQHRVLWGKDPFIGLHIDRTHLAYQVQQGIQGNLVRLRQRFIEGGGTEEATT
                     MLLPLSLTALLPCLRGLQRLAGHPALFQSDALLTAIRHMTGLDLAGLGDVLELKRGII
                     SPGPVEVPRLYERYAGNLEALIALIRPDGTVAPR"
     gene            29977..30714
                     /locus_tag="PK063_04485"
     CDS             29977..30714
                     /locus_tag="PK063_04485"
                     /inference="COORDINATES: protein motif:HMM:NF016424.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HMZ96333.1"
                     /translation="MKKRSLTINGLIPALWLLCVVMAAPLGHAREPVPNYDPQGYVSD
                     HAGVIEADWRARIRSVCQDLERKTGVEMVVVTVPTLKPYPSANDYAMGLYQKWGIGSA
                     QDEHGVLILLAVQERQAAVTMGRRMIPVMGGEVVGKVGHEYLDPAIKNGHFDEGLYRT
                     VVALASVSQEIRVGSTKKAHFRGLGFWITVTTASGALWFLWWLSRPDLRHPFGRIRKG
                     QYWGTGQGGFGGNFGGMGGGMSGEGWK"
     gene            complement(30856..31242)
                     /locus_tag="PK063_04490"
     CDS             complement(30856..31242)
                     /locus_tag="PK063_04490"
                     /inference="COORDINATES: protein motif:HMM:NF019013.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HMZ96334.1"
                     /translation="MKDETIPAAVRQYFEAIGKMDADSWVSCFAEEGISYEPGAPAPL
                     KGRAALRQFLVGVLGAFETIRMTADHVFQSANRVAVKFTGRGTGKNGRPVFFEGIDVF
                     EINQEGKIQTMWGYWNPATMMTQLQG"
     gene            complement(31434..31991)
                     /locus_tag="PK063_04495"
     CDS             complement(31434..31991)
                     /locus_tag="PK063_04495"
                     /inference="COORDINATES: protein motif:HMM:NF012791.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HMZ96335.1"
                     /translation="MTTTAPHDQSRFAPGHTSNRSVSPKNILIAVDDSNATIRVLHYV
                     GALLRETPSVAITLFHVLNPMPRELMEHGGSENPDMEHQLGEQLRKDQQEWMQMEETL
                     EYPILERALERLKDTGFPTERVMLKLGYAGDLVDTILDEVRAGGYGTLVITKHSQPDA
                     AHLFSNNVAERLSRELSGIALWVME"
     gene            complement(32296..32892)
                     /locus_tag="PK063_04500"
     CDS             complement(32296..32892)
                     /locus_tag="PK063_04500"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96336.1"
                     /translation="MALVQQNLVPGTGDHLITLDTETNLEWLSLNATANLSYMDVLGG
                     AGGYTTTYGFRYATGQEISLLHQHAGITKFGLTQVVPFPQSNHVAMETLIELMGGVAL
                     YPSVASGSVLVQTQGMMKFRGTGIPAPMTPMSVVQLWLFKHNPPSSYADSNPAGPAGN
                     RAPEIASYLIRNRVMPVGVVARGKSAKTVKTPRAKKKS"
     gene            complement(33191..33622)
                     /locus_tag="PK063_04505"
     CDS             complement(33191..33622)
                     /locus_tag="PK063_04505"
                     /inference="COORDINATES: protein motif:HMM:NF028108.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5069 domain-containing protein"
                     /protein_id="HMZ96337.1"
                     /translation="MDLRKTFPRSMKTRLAGYVHLARMIDKCRAVLAGTEGEYIYPCP
                     MDERLLEYAGITAEQFTAAVKTNVTDDGVAEWFRRTATPHRAADLEDWNGKLLGRGPS
                     SPESAAKFAKYRDAIDPSRTDITAWSDLQDLEEGRPVPRRG"
     gene            complement(33622..34299)
                     /locus_tag="PK063_04510"
     CDS             complement(33622..34299)
                     /locus_tag="PK063_04510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3386 domain-containing protein"
                     /protein_id="HMZ96338.1"
                     /translation="MEHVAAVDTQPTVADDPQARAILQRAFENTARWQPDFRGFSADL
                     SVNTNGQVVSGTVVVKGPREVSVQLPDEAIQKWAQEQIGMIAVHRAPRKFEESDGKHR
                     LTMESGEGHPLGRRLDIHGDGMQSFYRIKDNRITQINRKMPHVAFTINVEESSTTQDQ
                     KQLTTKYTVYYFAPKDSTLRNVESFTDTHVRIGASDLPAARRIISYENGAVLVRTLTF
                     TNHKLLA"
     gene            34543..34890
                     /locus_tag="PK063_04515"
     CDS             34543..34890
                     /locus_tag="PK063_04515"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96339.1"
                     /translation="MERRAASHTEEEEMNQRRRLLGLARKGDPKAISKLFELYQVRVL
                     NGDMLSKLNKSYYKAAAAQEQKAAQTPAKSAKGSQATHGSAKGSAKKSAAAAAPATKA
                     KPTKAATPKKRAK"
     gene            complement(34945..35238)
                     /locus_tag="PK063_04520"
     CDS             complement(34945..35238)
                     /locus_tag="PK063_04520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030163 - protein catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease adaptor ClpS"
                     /protein_id="HMZ96340.1"
                     /translation="MSTLTPVMTPDALDTTDVGTGDDLEARVIVFNCECHTYQQVIAL
                     FCKCIPGMNSSRAFELAWRIDHEGQATVYSGARKVAEEIGTKLAAGGLRVGVQ"
     gene            complement(35366..36058)
                     /locus_tag="PK063_04525"
     CDS             complement(35366..36058)
                     /locus_tag="PK063_04525"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96341.1"
                     /translation="MTSLPRRHALFYPFHLCAPGTLEYLLEHYGSLHFRDYMALRLTP
                     FMGTTAYQDRMGDEHPDLVSNGRIVQGYAVSGPLDDTAVAEIDRDFSDPAWRGLFHAG
                     LQADRRFQRGLFDLTHAMRIGSTLVPGPAALLRLLEPQRATEVCTVGLVKHLARSSAT
                     LEDAYQFEYGLALVKTAAAQVYTFRLARAHGLVPVTDSKTHYRLLSHTMAREGIDLPN
                     EYVVPSQSPAAP"
     gene            complement(36144..36341)
                     /locus_tag="PK063_04530"
     CDS             complement(36144..36341)
                     /locus_tag="PK063_04530"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96342.1"
                     /translation="MPVNMDPSKRRRRQPVESTASAADSETTQPKRFGEDTEADREKA
                     IAEAELKNLWDATEVIDMDSW"
     gene            complement(36415..37566)
                     /gene="hemW"
                     /locus_tag="PK063_04535"
     CDS             complement(36415..37566)
                     /gene="hemW"
                     /locus_tag="PK063_04535"
                     /inference="COORDINATES: protein motif:HMM:TIGR00539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HMZ96343.1"
                     /translation="MSQATAQGLYIHIPFCHQRCHFCAFYLEIHQARAAEEFVSALLT
                     EVRVYGESGVLRQDPLDSIYFGGGTPTTLSSQQLATLLATSAQVFGLAPDAEVTIEAH
                     PGSVSRDSLAHLREAGCTRLSFGAESMDQTELDRVGRPGSPSTTLHVMAMAREAGFTN
                     INLDLMYGLPGQTLESWATSLRQTIELAPEHLSCYALTIEEGTHLKSSIQRGLLPAPD
                     EELQNRMEDLAEEILGRAGYDRYEISNYCRPGCASRHNRLHWTGGHYLGVGPSAQSYI
                     GGRRFGNVSDLTAYKAALRNGRLPVSESDQLTQAGESCERLIFGLRLVDGISLTQTGA
                     LSFPELSREVDKLLADELLERKGDLVRLTTRGRRYADTVAVSLLTSLDE"
     gene            complement(37582..37836)
                     /locus_tag="PK063_04540"
     CDS             complement(37582..37836)
                     /locus_tag="PK063_04540"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96344.1"
                     /translation="MWSEDKSFVFRISLEAQFPDDYDGPLDEQAWLREWELQIKPVLI
                     KNLFDTLREYPAWKSHVRNRGKSPTEEIEVAMIRDFSPTP"
     gene            37916..38143
                     /locus_tag="PK063_04545"
     CDS             37916..38143
                     /locus_tag="PK063_04545"
                     /inference="COORDINATES: protein motif:HMM:TIGR02605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HMZ96345.1"
                     /translation="MPIFEYVCQECNHRFELIVQGQTVPACPSCKGTTLNKQFSAFGV
                     GATGGWPVVSNSGGGCGSCGDPRGPGACSMN"
     gene            38171..38491
                     /locus_tag="PK063_04550"
     CDS             38171..38491
                     /locus_tag="PK063_04550"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96346.1"
                     /translation="MMNDQEEQLRRAIGTLLQSDPLIKLLQEVRLGRMKATDAGLRAV
                     VESWIGTYAQVLKSQSLNAELLARLDPVPRLQVLVDAGVLSWEHSATCELRDLFRGLL
                     VPAA"
     gene            38511..39176
                     /locus_tag="PK063_04555"
     CDS             38511..39176
                     /locus_tag="PK063_04555"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96347.1"
                     /translation="MRTHLAMALLVLAWLMPATVSAEIPSPLRPLHTTLSAALATLPS
                     DSHLLLDREPIEQFLAALDGSPPDWPQIYGQGHHDPGHDERLFALNRERDARREGKEP
                     LQWLVTVVWLGEVSRFDEEEGGFRVALGPKFNRTAWGEVRFKHEDLPATLIASAGGAT
                     DDLKARMQRGERIDIDVVMCGRLIPEESLVYDFSHEVDGLGLIMPVVRIEAVAFVLAD
                     GSR"
     gene            complement(39215..39859)
                     /locus_tag="PK063_04560"
     CDS             complement(39215..39859)
                     /locus_tag="PK063_04560"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ96348.1"
                     /translation="MSILIIDDFQEERDLLHAILHRAGFGPLLPVATAQEGLTLLGIG
                     KRGKPGNGIDLVLMDLEMPGINGLEACEKIRMEEQLQGLPIIIITAHTAEKDIQAAYT
                     AGATDYIRKPVIPVELLARAATALSLKQEIDARKLREQELLERTKELDHAFEQMTTLH
                     GTLHICAKCKRVKTDGSYWQRIEDYLRRLARFTVKEAVCESCMHQAYPHLKRIP"
     gene            complement(39887..40639)
                     /locus_tag="PK063_04565"
     CDS             complement(39887..40639)
                     /locus_tag="PK063_04565"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ96349.1"
                     /translation="MASQLSRASDTGSEPICRVLLADDSRESQALIQLYLRGLPYQLD
                     VVGNGKEAVAMFQSQQFDLVLLDQHMPVMDGFTAARVMREWEASNERAPVPILTLTAD
                     SLVDVKTQAQAAGCTACLAKPIVKEQLLDAFRRFGARPSPKKPVVTQNNSPAGMAALI
                     DEEITRRRPLFLDHRRQDLKRMQEAIEQGDFDAIRIMGHRIKGLAGSYGFHDIGLAGA
                     QLEQAAREQDIAAMRRTIDRLTTLLTQARQAV"
     gene            complement(40805..41701)
                     /locus_tag="PK063_04570"
     CDS             complement(40805..41701)
                     /locus_tag="PK063_04570"
                     /inference="COORDINATES: protein motif:HMM:NF015722.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
                     /protein_id="HMZ96350.1"
                     /translation="MRRLKATPRWFLLCLLVMLSLYQAAWASLSSDDMVLVPAGEFTM
                     GASVDRGGLPDEQPIRLVYLGSFLIDRYEVTNAAYLQFVQATNYQAPANAADRLTLWE
                     QNRPLPGIEQHPVVNVSWLDAVAFCRWANKRLPTEAEWEKAARGTDGRTYPWGNDWSL
                     DKANSASYWAGKTVEFADSREWEAFWIKGLGAELSKAKGLKGEILTLPVGSFPGGASP
                     YGALDMAGNAAEWVQDWYNPNHYRSASLTNPQGPERGAIKAMRGGSWLKPAISLRTSD
                     RDWGTMDSRPSGTGFRCARDSY"
     gene            complement(41698..42450)
                     /locus_tag="PK063_04575"
     CDS             complement(41698..42450)
                     /locus_tag="PK063_04575"
                     /inference="COORDINATES: protein motif:HMM:NF025871.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing redox enzyme family protein"
                     /protein_id="HMZ96351.1"
                     /translation="MAQKRLTRAQFLERLLSIMDRKHHWAWPIIMGPGITKAQLKLHY
                     QQEYLVYVRDFPVLLARVHGQNPPPDVRRMLAENIYEEDTGGLSFGRSHPELFNEMMR
                     GLGFDSRVFLRATLLPASLRYRRWLEKVTASRDWVVGAAALAVFVEGSIKDRQEIQEP
                     SKPKTEAQIEAYIDAHPLIRHHKIEREHMDLIRAHQKVEAGHRQDAYTMVVNYAETRS
                     QQNAVLACVRQGLTLWAAYRDSIAKACKLTKP"
     gene            42498..42782
                     /locus_tag="PK063_04580"
     CDS             42498..42782
                     /locus_tag="PK063_04580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96352.1"
                     /translation="MKPITIQDSDEILNFLAEVALHGKGFTTDCLLDYVLEEGFTEPI
                     YLNASGEDPDAFYKNQPQAWAIYQVREWKRVLTVSGGPGKERRVQITETP"
     gene            43046..43276
                     /locus_tag="PK063_04585"
     CDS             43046..43276
                     /locus_tag="PK063_04585"
                     /inference="COORDINATES: protein motif:HMM:NF020967.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2007 domain-containing protein"
                     /protein_id="HMZ96353.1"
                     /translation="MSLCEPADVGELALIRSLLDGNGIPYAIQHEHIGALYPGVALLG
                     SRVMVSECDRQRAEILLSRLALQVREATSETD"
     gene            complement(43322..43774)
                     /locus_tag="PK063_04590"
     CDS             complement(43322..43774)
                     /locus_tag="PK063_04590"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96354.1"
                     /translation="MTDQTTSADPVSSLPPTAEPTPFIRQRPVRIIINSFLALFVVAL
                     IAFRFVPGWLDPDFSKHIESHRVMVGMDRKQVLDSWGSPNTMNVTHTSDGLRREEWIF
                     EDWESPAVVKHRYLYFEEGKLIGGHFSGSDVRLPLPTTPEPVKPKGHP"
     gene            43943..44605
                     /locus_tag="PK063_04595"
     CDS             43943..44605
                     /locus_tag="PK063_04595"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96355.1"
                     /translation="MGRGGWRRDRVWAWVTALGLCLLGYAGVDAEAGSLYVYTDAQGQ
                     AVLTDNLDQVPAAYRGRVRTMTDTDSSAPAPGPAPAIAGNKTSTSTSSGVIGDILSAV
                     AAKVGARTIKGLTAYQTAVVIVAGASSLILLLFIFLSANPAIRILCKVLLVVVGLSAL
                     YQVLAIDAPSLEALAGPPQQGAGQPVDNMLGRMRSQTEQSYRAQGERTASQLEPPEQP
                     AP"
     gene            complement(44614..45393)
                     /locus_tag="PK063_04600"
     CDS             complement(44614..45393)
                     /locus_tag="PK063_04600"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96356.1"
                     /translation="MAHQTVTRLIICCLLFFSLLGPECPSLWAGPYFEDGYLGLTQTE
                     LHAKLGLPQAVRDRKSALRVFTYYPISDWEQYFKKVVSPENGEDVYTFKRDGIDVRYS
                     FSFTFDPNDHNEQRPLFVRLVDIEFSPPVALSRIPQLVPEFRPTEDASAPVFRSNIML
                     LFFSGSPSADARFIVREKGKDALDWSLAFQMFALQGLPDPLTSKALIDRLEISTQSLP
                     LVKLRQRNTHEPVLNPYSKAFSQQPPPAPAVKKIPVPTYAE"
     gene            45580..>46610
                     /locus_tag="PK063_04605"
     CDS             45580..>46610
                     /locus_tag="PK063_04605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HMZ96357.1"
                     /translation="MPVHDIRELLRERILILDGAMGTMIQRHKLDEAAFRGERFKDWK
                     KDLKGHNDLLNVTQPSVIEAIHRQYLEAGADIVETNTFNSQSVSLADYGMEDLGYELS
                     KAGAECAKRAVAQVVKAQPARRCFVAGAIGPTTKTSSVSTDSNDAAARGTTYPELVQA
                     YGEQVRGLLDGGVDLLLVETIFDTLNAKAAFFAIQQLFAEGARQVPIMASVTFIQAGS
                     NRGFSGQTVEGFWNSISHVPLLSVGMNCALGPKEMRPLIEELSQLAPIFVSSHPNAGL
                     PNPLLPTGFPETPESLAPQLREWAQNGWLNIVGGCCGTTPDHIHTIAEAVRGVSPRRP
                     AKVEPFLRL"
     assembly_gap    46611..46710
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <46711..49418
                     /gene="metH"
                     /locus_tag="PK063_04610"
     CDS             <46711..49418
                     /gene="metH"
                     /locus_tag="PK063_04610"
                     /EC_number="2.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008705 - methionine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HMZ96358.1"
                     /translation="RGVSPRRPAKVEPFLRLSGLEALTVRPESNFVNVGERTNITGSP
                     AFSKLILAGDYDKALTVARQQVEGGAQIIDINMDEGLLDSKVAMQKFLRLLAAESDIA
                     RVPIMVDSSKWEVIEEGLRNIQGKGIVNSISLKEGETKFLEQARLIRRYGAAIVVMAF
                     DERGQADSVARRIEICERSYRLLTEQVGVPPQDIIFDPNILTVATGLEEHNNYAVDFI
                     EATRWIKAHLPLAKVSGGVSNISFSFRGNNVVREAMHAAFLYHAIQAGLDMGIVNAGQ
                     LAVYEEIPKDLLALVEDVLLNRRPDATERLVTFADTVKQKGKAAVKDDEWRQRPVEER
                     LAHALVKGLTDYIDQDVEEARQKSARPLDVIEGALMAGMNIVGDLFGSGKMFLPQVVK
                     SARVMKKAVAYLMPFMEAEKQRLGTSRANGKVLLATVKGDVHDIGKNIVGVVLGCNNY
                     EVIDLGVMVSCEKILETAREQQVDMVGLSGLITPSLDEMVHVAKEMTRQGFTVPLLIG
                     GATTSKAHTAVKIAPSYANTTVHVLDASRAVGVVGSLINKQQEQEFSASIRADYDRIR
                     QAHQDRGSKALRTVEAARTHRMPTDWASADIPTPSFTGLRQIDRMPLRELVPFIDWTP
                     FFHTWELRGRYPEILEDATVGPKAKELLADAQALLEEIIRGELLTARGVYGLFPANSV
                     GDDIELYRNGDRRDVLTTFHTLRQQTEKPADQFNLALADYVAPKDSGRGDYVGAFVVT
                     AGIGVEALCAKYEKDHDDYNSIMVKALADRLAEAFAEWLHKQVRREWGYGKAETLTNE
                     DMIRERYRGIRPAPGYPACPDHTEKRILFDLLQAESQSGVTLTESYAMLPAAAVSGLY
                     FAHPGAKYFAVGKINRDQVEDYAARKKLSVGEVERWLAPNLNYDA"
     gene            complement(49527..50024)
                     /locus_tag="PK063_04615"
     CDS             complement(49527..50024)
                     /locus_tag="PK063_04615"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96359.1"
                     /translation="MKRTSRNWIAYLCENLASSGMMPTWEAATYLTDNLFGDKPNPRL
                     LRTTCPYEDTTHLLQRLYQPLVAAATRDMPLPAAAMIHVFTDISLTGKSAVLVVYFPG
                     PTQPHQLLLLDAAKAWELVFENSDEFNTWAEARYHSIKAALAKILSGVAPSPTLPASL
                     EAVKN"
     gene            complement(50021..51199)
                     /locus_tag="PK063_04620"
     CDS             complement(50021..51199)
                     /locus_tag="PK063_04620"
                     /inference="COORDINATES: protein motif:HMM:NF014069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ96360.1"
                     /translation="MSIPSVSEVTTQQSILENRHILIVDDEEPIRRLLGYLLEPHGYQ
                     VTLAGEAREARQRMEDGYYAMVLCDVNMPGESGMDLIRHILTQYPNTAVIMITGLDSP
                     VLANAALDMGAFGYIIKPFEANEVLINVANALRRRKLEIENAMHRENLEEVVRTRTIA
                     LQQALEWLERSEKELRLSREETIQRLAIAAEYRDSSTAQHIQRMSHYCELLARRYGLS
                     PDRCDLIRTASPMHDIGKIGTPDHVLLKPGKFTPEEFKVITQHTEIGYRILAGSDSDL
                     LKVAALIAWTHHERYDGTGYPRGIKGEEIPLEGRIVAIADNFDALTTQRVYKPAFDFD
                     HAKELMLKERGKHFDPDLLDIFFESMADVKRIFDQFADPSWLSSSRHRAITHDQGEAV
                     "
     gene            51653..52396
                     /gene="rph"
                     /locus_tag="PK063_04625"
     CDS             51653..52396
                     /gene="rph"
                     /locus_tag="PK063_04625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004549 - tRNA-specific ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HMZ96361.1"
                     /translation="MTSGAGLGRIDGRRRDQIRPVKVTRNFTKHAEGSVLIEMGDTKV
                     ICTASVEEKVPPFLKGKGTGWVTAEYAMLPRATHDRSPRESVKGKQGGRTLEIQRLVG
                     RALRAVIDTGRLGERTIWIDCDVIQADGGTRTASITGSFIALADAITVLKKKDLLKVN
                     PLTDYLAAISIGKVGGQVMVDLAYEEDSHAEVDLNLVMTGAGQYVEVQGTAERTPFNK
                     KDMDEFLDLGWGAIRELVDLQKSLIGALS"
     gene            52399..53010
                     /locus_tag="PK063_04630"
     CDS             52399..53010
                     /locus_tag="PK063_04630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="non-canonical purine NTP pyrophosphatase"
                     /protein_id="HMZ96362.1"
                     /translation="MQIVLATRNQHKKQELVALLGGLDITIRTLDDFPEAPEVVEDGE
                     TCEANAMKKAVEISRFTGLPAVADDTGLEVDALGGRPGAFAARYAGEHATYEDNCRKL
                     LQELSGIPPARRGARFVTVAAIAFPGGKTMSAKGLLEGVIAESVVGSNGFGYDPVFIL
                     PEYNQTLGQLPPEVKNRISHRARAFAQARTLLQQAMAEHSVGA"
     gene            53001..53077
                     /locus_tag="PK063_04635"
     tRNA            53001..53077
                     /locus_tag="PK063_04635"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:53035..53037,aa:Pro,seq:tgg)
     gene            complement(53178..54563)
                     /locus_tag="PK063_04640"
     CDS             complement(53178..54563)
                     /locus_tag="PK063_04640"
                     /inference="COORDINATES: protein motif:HMM:NF012296.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HMZ96363.1"
                     /translation="MQDIDSNPSFTLTDVPGGLPWLGHLRSFKHQPLRTMSGWWRQQG
                     DAVRFRLGPKTIHLFSHPALAEEVLLSQAERFGKVYEQQRPTGLALVLGNGLVTSSGE
                     VWKRHRRIIQPVFHRSRMAAMADRMVQVGEQRLAGWATHGEQPVDIAAEMMQLTLEVI
                     SQTMFHTSVAQHMDQISHSLRVSLKYAFDSFHNPLHLPVWVPTARNREFSRALKFMDT
                     LIYELVAARRQSGAHYDDLLNLLLQARDEETGMGLTDQELRDEALTIFAAGHETTANA
                     LAWTWYLLATHPEVRTRFHTEVDLVLRGRTPTADDLQHLPYTRAIFDESLRLYPPVPA
                     IQRKSMTQTTLGGFTLPANAIVLVGLYNLHRHPAFWADPEQFLPERWLDGERPPSRCA
                     YLPFGVGPRACVGTHFATVEGPLLLALIGQRYDPQLAQDHVEPEVMVTLRPKNGIRMT
                     LQQRHQSVGSE"
     gene            complement(54758..55615)
                     /locus_tag="PK063_04645"
     CDS             complement(54758..55615)
                     /locus_tag="PK063_04645"
                     /inference="COORDINATES: protein motif:HMM:NF017102.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HMZ96364.1"
                     /translation="MPRRTRAASPTRPARAKDAVLDYPGYALKSGILAPSTIRAVQQR
                     LNQVGCGPISVSGVFDRATQEAVRLLQARSVDGQGQSLKIDGVVGPLTWAALFGAHRV
                     PSIATTPISALMKATLSIAASQVGVMEDPSGSNRGPKVDEYLKAAGIDPSTGSYAWCA
                     AFVYWSFKQAATRLGTTNPAIRTAGVLDHWKKAGQAGVTRLVAGQILDDLSLLKPGLV
                     FVINTGGGHGHMGLVEDFRDDRLVTIEGNTNLPGDREGVGVFRRSGRTISDINQGFLS
                     YDSLPHASS"
     gene            complement(55883..56287)
                     /locus_tag="PK063_04650"
     CDS             complement(55883..56287)
                     /locus_tag="PK063_04650"
                     /inference="COORDINATES: protein motif:HMM:NF012514.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HMZ96365.1"
                     /translation="MAVRNVAIFILYTSSGQLLLQHRTPDAYRLPNYWAFFGGGIEPG
                     ESPSDALKREVIEELSYHVQDPHFLMTQLFREGEDENTKYVFVERYQGQPLELGEGQA
                     MGWFLPDETHDLKMIDHDRAIVERVRQYLRDR"
     gene            56934..57335
                     /locus_tag="PK063_04655"
     CDS             56934..57335
                     /locus_tag="PK063_04655"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ96366.1"
                     /translation="MLTPQRPLKLLIIDDSPDFQLLIKTYLEDFGIVCLFATDVVQAT
                     STAVREQPNLILLDIGLPGGGGLLLLERLRANLRTAKVPVIVITAQTTDGLESKARSL
                     GAEEFLHKPVEKDVLIDTLRRVLSRPPTQQA"
     gene            57589..58179
                     /locus_tag="PK063_04660"
     CDS             57589..58179
                     /locus_tag="PK063_04660"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96367.1"
                     /translation="MIRLARKPDGMFSDLLDSAITQIVNDYLTSANARDQEDWLCASM
                     PRAARFFTAPQAREQLLAMQKIYHDERLYEVTKYHWLLLYECLETFAQGFNEQPVGWL
                     AQKYGIEKIDFHRLVDLFFWDTSFLMDHLAKMSRQETRTMLIWPESVGLAAGFKTHPD
                     ELAFILCDEGVTEEFAAQKDVPAWSIGSKSYPLPHT"
     gene            complement(58306..58722)
                     /locus_tag="PK063_04665"
     CDS             complement(58306..58722)
                     /locus_tag="PK063_04665"
                     /inference="COORDINATES: protein motif:HMM:NF016807.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BLUF domain-containing protein"
                     /protein_id="HMZ96368.1"
                     /translation="MFCLVYASSATRPFSPSQLTDLLASCHANNSRLGITGILLYKNG
                     NFMQALEGEEEAVLKLYAKIFQDERHSGVLTLLQQTIPARQFPDWSMGFRDLNSPEVR
                     SLPGYNEFLNMPLTGAEFSSDPTYCQRLLTIFKKMM"
     gene            59077..59790
                     /locus_tag="PK063_04670"
     CDS             59077..59790
                     /locus_tag="PK063_04670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HMZ96369.1"
                     /translation="MMRPPRRQSKAALVFLFDVDETLLDDQRVLSDLRRHLRREVGRE
                     GDRRYWNILQRLHRALGYADYLGALQKYRQSYPHDPHVLTLSSFLINYPFAKRVFPQA
                     MRVITRCRRVGSVVILSDGDVVFQPHKIQQSGLAAAVDDHVLVYVHKEEQIRNIEVCY
                     PADHYVVVDDNVRILNVIKKIWRERVTTVWVRPSSSGTGRNGIHAHAHPDLTIHSIGE
                     LNKERLRAIKLLQKEQSHS"
     gene            complement(59848..60084)
                     /locus_tag="PK063_04675"
     CDS             complement(59848..60084)
                     /locus_tag="PK063_04675"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96370.1"
                     /translation="MSKHKRRDKHRPGSMDEMIVNAIDQGLLRSAATAGQLVMEQVLK
                     TDPEAKSLLETLVKQRLKQVLRNLDESGKANGKN"
     gene            62239..62315
                     /locus_tag="PK063_04680"
     tRNA            62239..62315
                     /locus_tag="PK063_04680"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:62273..62275,aa:Arg,seq:tct)
BASE COUNT        12715 a        17106 c        18782 g        13812 t
ORIGIN      
        1 gttggtgagc aacaggcgtg ccacaacaga ttgcttcggc gttcttctta gttgattgtc
       61 gggaatcgct cagcggagtt cggtgagaat cccgtcagga tatcttgcag agccgaccct
      121 aacggatcaa acgcgaatag gcaagcaaaa atttcactcg tcgcacgtat cttgcgtggg
      181 ccgttctctc gtacaaatgc tctaggaaat tttttccgcc tgtagggtcg tggcacttcg
      241 tcgtacaaaa tcggaacgcc tgtcttgcga cgatgaatcc tttccagtcg tcctcggacg
      301 atcgcatcag gagagtcggt tatagagccc actagggccg agaaagttgt tgaccatgca
      361 cgataggtag ggtatctgtt ggcgcgctgt tccggccggg atacgtagtc tcgcggtcat
      421 gcgaacgagt ctttggcccg aatggttagg gagtgcccca cctatgatcc cgctacgatg
      481 tctgttctgt gcgatatgcc tgtgtgtgac cgcgtacact gctgattcgg cggaggcgca
      541 ggttcctccg gcccagtcct cgtcggttgc gcaagtcgat ctcaaaattt ccgagtggtt
      601 cagtcaaggt gaaacggttt ggagccacaa tgcctcgggc ctggacccca acctgggcaa
      661 tcccagttca aaactgaaat acaaagatac cggcaccaat gtcaccgaga tcaccggccg
      721 agtgcagttg aaaaataaga tgtttttccg cggcgccttt gggtacgggg ctatcggcgg
      781 cggccgtctt acggatgatg attttctgag tgcccaggga gctgcctctc aaggggcgac
      841 cgtgagcgga gaacatcgtt tttcgcgaac ctacagcgat atcggcggtg acaatctctg
      901 gtacctcaat ggcgatgtgg gcgcgacggc ccataccttc caggacaaca agggaaccct
      961 gggggtgttt gtgggattac agtattggcg ggaacggcat gtggccacgg gcgtcactca
     1021 ggcggaatgt acgaccgcct cagcacccag ttcggagttt cgctgttctc ctgctggaac
     1081 ggtcggattt cgcaatcagg cagtcattac caacacgacc acatggtttt ctggtcgcct
     1141 tggtggagag ctggaatata agttcgatcg tcggatcagc gtcgaggcca aggtggcgat
     1201 gctgttgtcg tatttagata atgaggacgt acaccacctt cgcacggacc ttgcgcaaga
     1261 tccaagtttt cgaatgaccg gcctgggaat cggcaccacg tcggacttta atctgcgagt
     1321 gaagctctgg gatcgtctgt accttacggg tggttaccgc ctgtggtgga atcgcgtgct
     1381 cgtcaatgat cagtggaaat tgtacgggtc agacgggtct acggcctccg cgcccttgac
     1441 ccaattccaa acgcttcgac atggcccaac ggtgggcctg acctatacat tctaagggac
     1501 gaagaggctc tcccgtgacg tcgattnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1621 nnnnnnggct gaccgtacgg aatgccggca gttcgaaaca gaggcgtgag cttctcgttg
     1681 gggtgaagat aaccggcccg cagcggaact gatcgcttgg tgtgtcgaat gagcgagcag
     1741 gggctcgggc ggatcgcggt caaccagtcg gcaatgtcct gcggattgcc gattgaagcg
     1801 gagaggagca ggaggcgagc ctgcgagggg caaaaaatca aggtttcttc ccacaccact
     1861 cctcgttcgg gatcggccag gtattgggac tcatccataa tgaccagtcc cagcgtgtct
     1921 aaccgcacat caatctctcc gccggctgcg tcatacagca gattgcgcag gatctccgtc
     1981 gtcatgatca agaggggagc ctgactatgt tcgcggcggt cgccggtcag gatgcccacc
     2041 tggccagggc cgaatacgcg tgagaactcg gtaaatttcg tgttggaaag cgccttgaga
     2101 ggggaggtat agatgacggt gcgattctcg cgcatcgcgc gagcggtcgc ttcaatcgcc
     2161 acgtaggtct tgccgctccc ggtcgggacg ctcacgacca catcggtctc tgccagtttt
     2221 gccagcgcct ccacctgcca cgcatcggga acaaacggtt gcggcggcgg cacgccaatc
     2281 cctgacagcc attcatgcag cgagacaggc ggttcgtgat gatggccatg atcatcagtc
     2341 cggtgcggac gcgacgtcgc agggacggct tggcgtgatc gtgcttcagg tggtcgtgtt
     2401 ttttcgacgg gcactggttg tgggcgctgc gcccgttcgt cgatgagggt ctgcaggtcg
     2461 gactccagtc ccgggcgatt ttcggcggac gcttgaagga gcaaatcgac cagcttgcgt
     2521 tttccggaac ggaaatgccg gctgatccgt ccccgcgcca atcgatggag cagagagacc
     2581 ggttgttgca tcagcagccg ttcgagttcg tgggtgttca cggcaattcc tccagcacac
     2641 cccggcgcat tgccgtgatc gcgtgatcgg ctgattccgc cagcgaagga tgggtcgctt
     2701 ttaatgtctt cagttgggac aaaaactcga ttgtacgcgc gaagagccgg aacatgtcgc
     2761 cttccgccat cgtcgtcagg cgggccagtc cgatccaggt gagcgtctga tcggaaaccc
     2821 accgttcggt gagcgccgcc acgtcggccc gcaacatcgg cggcgcttcg tggggcgtca
     2881 agctctccgc cagcttccgc acttgaaaca gcaaggtcac gagcccggcg cttccacgcg
     2941 gaaacgatcc gggacgatcg tcgtcatggg caatgctggc catgacggcc gccaggagcg
     3001 ggggatcgat ggcgccgaag gcttccgccc ggatcaattc ggtgatcagc agcgaatgat
     3061 cgatccgaat cagccgcgcc cattccccgt cggcggtgag ctgggcattg gcatggaggt
     3121 agccgaattt ttccaggacg tcgatacgct cttgaaaccg gtgccacaaa ctggtctgga
     3181 gggcctgaat cgatttgata tggcgttgga tctcctggcg cacccgcgag gcgcgtggga
     3241 aatcacgctg acaggcctgg cgcgaggggc aggtcgggca ggggaagtcc cccagcgttt
     3301 gaatgatgga actgtcgatc ggcgtctctt cgtgctggtg cgcgagaatc ggaaggatcg
     3361 gcagcctcgg cggaagatcg gtcagatgat gggtcagttg ttccagcgcc tgcggcgtac
     3421 accagggata ggttgatgtc tcttcgcagt cgaacgtccg atcgaagacc tgtgtcacga
     3481 tggaggccgg gcattcattc agcgagccac cttcccgcag gagggtgacc atcggcgcat
     3541 gttggccttt gctgcggtac tggcgcagga tgatcccgcg tccacgggtg acacccacga
     3601 cgcgcccggg cgtcaggaag tggaggcgcg ccgcaacatc gggcgattcc tgcctggtga
     3661 acgggctccg gggcttcttg cgtttccgcg cctgctcgaa cacctgccac tgcgtaatcc
     3721 aatctgagca gacacgggga ccgaacggct ccatttcggc gcgcaggcta tcgagtttgg
     3781 tttcgagcac ggccgtgcgc tggttcaact gaaattgggc aaagcttttg gccaggatgg
     3841 attgaatctg ttcgcgtgga tgcgccttga gcaggttcaa gaccatgggg taactgatca
     3901 cgaattggct gtggatcgcc tccggctgcc ccgtcaggcc cttggtcagg accgtgagat
     3961 cgatataggg agacggggtg atgaccgcga acccgacgag atctttgccg cggcgaccgg
     4021 ctcggccggc caattgctgt atttcgctcg cggtgagatc ggtaaaatcg cgcgctttac
     4081 gaatgctgga ttgcgtgacc accaccgtgc gggcaggaaa gtccacgccg gctgcgagcg
     4141 tggtcgtggc aaagacggca tccagcgatc ccgtgcgcat caattcttcg acggcaattt
     4201 tccaggaggg caaatgtccg gcatggtgcg cggccacacc gatgcgctgg accgtctcga
     4261 tcagcggatg ttcggcaatg ctgggaaact gctcggtcac ctgcgtcagc acgcgggcaa
     4321 tctgttcctg ttgcgctttg ggcagcgtca cctgactgcg ttcgaaggat tgcatcgctt
     4381 cgtcgcaggc ccgtctcgag gtgagaaaaa tgatcgcagg ggtgaggttt cgttggcgga
     4441 gggtcgcgac cagatcaacc ggatggatcg acggcggcat gcaatttcat tccctttgag
     4501 atgaccacca atcccgaatc ggtgactttg aaacgttgac gatccgccac cgggtcgaac
     4561 ccgatcacgg ttttaggcgg aatcacgaca tccttgtcga tgatggcgcg ccggatacgg
     4621 gcatgttcgc cgatgaccac gttttccatt acgacagact cgcgtacgtc ggcatgatcg
     4681 tgcacacgta cgtgcggcga cagcaccgag ttctgcacgc ggccgcctga aataatgcag
     4741 cccccgcaga cgatcgaatc caatgcgacc cccatccggc cgccctgaaa gtcctgtgcg
     4801 aagacgaact tggcaggggg aaattgccct tggtaggtgc ggatgggcca atgctggtcg
     4861 tacaggttga attgcgggtc gacggagacg agatccatat tggcttccca ataggcgtcg
     4921 agcgtaccga tgtctctcca gtagttcacg gccttcttgt tctcgtcttg aaatttgaag
     4981 gcatagacgc ggcattcctt gatcatccgc ggaatgatgt tcttgccgaa atcgtgtttg
     5041 gtgccttcct tggcatcgcg aatcagctgc tctcggacga catccgtgcg gaacagatag
     5101 atgcccatgg agacgaaggc ctgggtcgga tctccgggaa tgtgcatcgg atgctcgggc
     5161 ttctcgtcga agctcaagat gcggcggtct tcatccaccg cgatcacgcc gaaccggttg
     5221 gcatccgcaa tcggggtttc gattgcgccg acaatggcat ccgcctgttt ttcgatcagg
     5281 aggttgtaca tatcggcgta gttcatcttg tagatatgat cgccggccag caccaggaga
     5341 aactcggggt gatcgttatc catcaggaag agattctgat agaccgcatc ggcggtcccg
     5401 cgataccact cttcgctgat ccgctgctgc ggaggaaccg acacgatgta ttcgccgagt
     5461 tcgggattga gaatgttcca tcccgtccgg atatgccggt cgagagaatg tgatttgtac
     5521 tggatcagca cggcgatctg ccggagaccc gagttcaggc agttgctcag tgtgaaatcg
     5581 atgatgcgat atttaccgcc gaaggggacc gcaggttttg cgcgctggtc ggtgagaggc
     5641 tggagccgtt cgcctttccc tcccgccagc accatcgtga agatgttcgc catagatgcg
     5701 ccgattgtag caggacgaag ggggaataga aaggacgcag aatgattgac ttcaactccg
     5761 actcggataa tactacgaat caacatgcgg ttccgacagc gggtcgggcc gaagagaagg
     5821 agcggcgatg aagaagcaga atgctcgtcc ggcgatcatg aaaccagcga tcgagccggc
     5881 caatccgatg atggaaatgg tgtggcggct ggagcgactg gagcggcaag tgcagcgcct
     5941 gtccgagctc gtgcggaatc acgccgagga taacgaccgg ctcgtgcgca tcgtggcgga
     6001 agatcgcgat gtgatccggc gtgaattgtt gcggaaacat gagcatcggg tgcgcgtgcg
     6061 gaagcatctg cgcgacgtca gttccaaagt cgatctggag cattgatccg agaccgtcgg
     6121 tgcggcggtc tgaccccagc cctcgatggc caccttttcc acttctcctg tcagtgcctc
     6181 tggcccctct ctttcgtcga cagtcccgac gatcgacatt cgagccatcg tgcgacatca
     6241 tggcccggtg gcggccgtgg atcacgtcag tttccaggtc cggcggggag aatttttttc
     6301 cattctcggc ccgagcgggg ctggaaaaac gtcggtcttg cggatcgtgg ccggtttcga
     6361 agatccggat gcaggcgacg tgttgatcga cggccgatcg atgctgggag tcccgccgaa
     6421 ccgccgtccc gtcaacctgg tgtttcagtc ctacgcactc tttccccatc tgaccgtctt
     6481 tgagaatgtc gccttcggcc tgcggatgcg ccgggttccg gctgcgctca tcgccgagca
     6541 ggttgagcag gccttggcga tggtcaagtt ggtcggcaag gagaggcgga agcctgccca
     6601 attgtccggc ggcgagcagc aacgtgtggc gttggctcgg gcgttggtca ataagccggc
     6661 tgtggtcctg ctggatgaac cactcgcggc cctcgatcaa caactgcggc aggcgatgca
     6721 ggtggagttg aagtcgattc aggaacaggc agggctgaca tgcgtctgcg tgacgcacca
     6781 tcaggaggag gcgatgatga tgtccgaccg catcgccgtc atgcaccaag ggcgcatgtg
     6841 gcaggtgggc actccacgcg aagtgtatga gaacccgcgc aacctgtttg tgtctcgatt
     6901 tctcggggtg tccaatgaac tgccggggcg ggtggatgat gtcgtggaag atgggcatct
     6961 ctttcacccg gccgatgatc aggtgcccgc atttccggtg cgcgctggtt ccgaggcgtc
     7021 acccggtcat tcagccacct ggtcgattcg gccggaacgg ctcaggatgt cacgggaacg
     7081 acctgccggc cgagacgcgg tgctgaacgg cttcatcgag aaggtgctct ttgccggcag
     7141 cgagacaaag tatctcgttc gagtgggccg cgataggctg tgggaagcga gaacgaccgg
     7201 cgctggcgaa tcgccccatg ctccggggga tccggtcttt ctgcactggg cctcgggtga
     7261 cgggcgagtg tttgttgagt gaccatgccg tctgacgatg tctcccacgt ctctcccgcc
     7321 tcgcaagact cctgccgctc ttgctggctc gccgctcccg gcttgctgtg gttagccctg
     7381 ttctttctcg ttccactggt gttggtgttt gccatcagct ttgcctcgcg cggaacctat
     7441 ggcggcatcg tctgggagtt tacgtgggcg aactatgttg atctgctgca tccgctctac
     7501 ggcaaaatcc tcggccagtc cttgtggtac gcgacactga cgacggcgat ctgttttctg
     7561 ctgggatttc ctttggccta tgtgattgcg cgcagtccgg cacgctggca accggtgttg
     7621 ctgctcctgg tcatgctgcc gttctggacc aactttctcg tgcgcaccta cgcgtggatg
     7681 atcatgttgc ggcatgacgg cctggccaac aatctgctgc tcggtctcgg actcattacg
     7741 gagccgctgg aattgctcta taccccgacg gcggtggtga ttggattggt atatgggtac
     7801 ctcccgttca tggtcttgcc gctgtacgtg gcggtggagc gactggaccc tgtcctggtc
     7861 gaagccgcgt gggatctcta tgcatcccgc tgggcggtgg tgacgcgtgt ggtgataccg
     7921 ctcacgatgc cgggcatcgt gggcggatgc atcctggtat tcattccgtc gatcggctcg
     7981 ttcatcacgc cggatctttt gggtggcgcg cgcagcatga tgatcgggaa cttgattcag
     8041 cacgaatatc tggtcgtgcg tgactggccg ctcggttcgg ccgtgtcttt cgttctgatg
     8101 gcgatcgtga tggcggcggt ggtcttgtac taccgtcagg ccagcccggg agacgggcca
     8161 ttggagggac ggtgaagcag cgatcgctcg gcctcaatgc cgtcagcctc ctggcgatgc
     8221 tgtttcttta cgggccgatt atcgtacttg tgctgtactc ctttaacgcc gcacacctct
     8281 caatgacctg gcgagggggg accctgaaat ggtatgcggc attggtccat gatgaggcct
     8341 tgctcgcagc gacggcgaac agtctgctca tcgccctggt gtcgaccatc ggcgccaccg
     8401 gtctcggagg gctgctggcg ctcggcatgg aacagatgcc gcatcgccgg caacagcttc
     8461 ttgaaggcgg tctcgtgctt ccgctggtca ttcctgaagt gatgatgggc gtcgcgctga
     8521 tgctgttgtt tgtgacggtt cacgtgccgc tcggcctcac caccgtcatc ctcgggcaca
     8581 ttgtgttcaa tatcccgctg gtcaccatca tgatccgcac gcgactgagg aaactcgatc
     8641 ccatgttgcg cgaagcggcg gcggatctcg gcgccgactc ctggcaggta ttccgccatg
     8701 tgaccctgcc cttattgcgg ccggcgatct ggggtgcggt gctggtcgcc ttcacggtct
     8761 cgctcgatga ttttctggtg acgttcttca ccgccggccc cggctcgacg accctgccgc
     8821 tgaaggtcta ttcgatgatc aagtccggcg tgactcctga aatcaatgcg ctatccgcct
     8881 tgctgttggt ggtctcgatg ataggtgtcg ccgcttccct gtacctgcag cgtcgcgagg
     8941 tctgagtgag ggcaacgatt cgcgagaggg tcctgtggtg tttatgcctg gtgtggctca
     9001 ccgggtatct cacggggtgc gggcagcgct tcgatgagaa ccgggtcgag actcgacctg
     9061 tgttgcacta ctttacctgg tcggactacg tgagcccgga catcattcag gaattcgaac
     9121 ggcgcgagca ggtcaaagtg gtgatcgata ctttcagcag caatgaagag ttgctggcga
     9181 aattgcagag cggcgccacg ggatacgacg tggcggtccc ttcggatttc atggtggcga
     9241 tcatgatcca gcagggcttg ctcagtgagc tggatcaagc cgcgttgtcc aatacatccc
     9301 agcttgagcc gcatctccaa accctgcctt tcgatcccga gcgccgctat tccgttccgt
     9361 atctctgggg caccgtgggg atcggatacg attccgcgag cataccgacg ccccccgaca
     9421 gttggtcgat cctctgggat gcgcggtaca agggccgcat cagcatgttg aacgaccagc
     9481 gcgaagtgtt cggggcagtg ttgcggtcga tggggcaatc gatgaacagc acggaaccgc
     9541 aagtgattga gtcggccaaa gaccgcttgc tcaatcaaaa gccgctggtg aagacgtata
     9601 cgagtgatca ctacgaccag ctgctcgcct ccggggaggt tgtgctggcg catgggtggg
     9661 gagggcaggt ggcccgtgcc atggccgatc gcccttccat ccgttacgtc gtgccaaagg
     9721 aaggcgccac catttgggct gattgtctgg tggtgcttcg gacggcgccg cagaaggcac
     9781 tcgccatgcg gttcatcaac tatttgatgg agcccactgt ggcggcacgt acgtcggagc
     9841 gactgcgttt tgcctccacc tcccggtcgg cccgggaact tgtggatgcc gcgacgcgag
     9901 acaatcctgc cgtctatcct tccctcgatc aattggcacg attggagtgg atgcgtgatg
     9961 tgggcaaggg aattcggctg tacgatcgtg cctggaccga actgaagatg caatgattgc
    10021 ggccatgctc attatttgaa atgctgcgaa gaatcagtat aatgcgtgcc ctgtcctcgg
    10081 ttgatcgata ttcccgcacc atgcgtgacg acatgtctca gcacaagaac ggctccccga
    10141 gtggtgtcag gttatggcat cagcatcccg ggctgtgggt cctgattgcg ctgctgggtc
    10201 tgaccctatt cgggagcgga tgggtccggg ccgccgaatc gaccacgatc ccggccggtt
    10261 catttgctcc accggtcgtc cgtctgaatc tgtccgaggc ggtggccctg ttcctcaaac
    10321 agaatttcga cctcctcatt gccaagtacg gcatcgagtc cagcaaggga caacagatta
    10381 cggcgcgcct ctttcccaat ccggtggctc agatcggcac cgtggcctcg tttactcatg
    10441 gcaataccgc ggcgaacagc ggcgccctca cgatgcaggt gcagcaattg tttgaattgg
    10501 ccggcaaacg cggctatcgc atcgaaagcg ccggtttcgg cgtgcaatcg gcggaagcgg
    10561 attttgaaga tgctatccgg cagctggggt ttaccctcaa agacgcctat taccgcgtgc
    10621 tggtggcgca gcgcagattg gccttggcgg aggaaaaccg ggatcgcttc gcccgcatcc
    10681 tggacgtcaa tacgattcga ttcaagaagg gctacattgc cgaggtcgac ctgatccgta
    10741 tccggctcca ggtcgtcgat ttccagtccc aggtgatcga atcgattcag gaaggcgaat
    10801 cggcacgggc cgatttgcgc cagttgcttc gtctctcacc ggcgtcgaag ctggaattga
    10861 ccaccgagat ggactaccgg cgggttgatc cggacatggg aaaactgcgc tcggtggcgt
    10921 tggatgtgcg ccccgatatc agaagcagac gggcgctcgt ggcgcagcgt gaagcggatc
    10981 tcaaactggc gaaggcattt cgggtgccgg atctgaccat tggcgccggg tattcgatac
    11041 aaggaccgcg cggaccggac aatccccaga tgggcatctt gaatctgggc gtgcccttgc
    11101 cgctcttcaa tcgcaatcag ggcggtatcg tgcaggccga agtcggtgtg cagtcggccc
    11161 aggcggaatt ggatcgcacc gtcaaccagg tggaaaacca ggtggatgtg gcctatcaca
    11221 atctcctgca gagccgtcgg ttggtcgagg cctacctggc tggggtcttg gaagatgccc
    11281 gttcgacgtt taccatcgtc gagcgcgcct acgaacgcgg aggcgccacg attctggatc
    11341 tcctcgacgc tgcgcgcacg tcccgtacga tccaacaaaa ctttatcgaa gccctgtttt
    11401 cgtaccagcg gaatctgttc caattggaaa gctctgtggg gcaggagatt acgtcatgaa
    11461 ttccggcgca atcccggtca taggcctgac cgttgtgctg ttgttctccg cttgcagtca
    11521 aaaacaagac tctgcgcctt ccccgccttc cgcctcttct gaaccagtcg tcgctccggc
    11581 cgttccgccg tccgccggcc aaatcgaaac cgcagtcgtc gacttcaaac cggtccagcc
    11641 ggaattggtg ctcgtcggga agatcgccta tggcgaagac cgatattcca aaatttcctc
    11701 ccccttgcag gggcgggtgg tggaagtgcg cgccaaattg ggtgatcggg tcgaggccgg
    11761 ggcgacattg ttggtcatcg acagctccga cattaccgcg gcctattccg aattcgtgaa
    11821 agaggcgtcc gagttggagt actcgacgcg ggcccaggaa ttggccaagg aactctatgc
    11881 cacgaaggcg ttggcgctga aagacctgaa gcaggccgaa aacgatttga tcaaggcgcg
    11941 ggcggaattc aggcgcgcca aggagcgact gttgtcgttg cgcattcctg ctgccgagtt
    12001 ggaaaagccg ctggcgcagc agcggattac ctcgcgcttt gagatgaaga gtccgctgac
    12061 gggcaccgtg gtggaacggg ccgttacgcc gggacagtcc gtgggaggtg atgtcggcca
    12121 ggtactgttt acggtcgccg atctggaccg attgcaggtc gtggcagatg tctacgagcg
    12181 ggacctggcg ttggtgaaag tcagtcaggt gggccgcatc aatgtggagg cctatccggg
    12241 aaccgatttc gcgtccgtgg tcgcgtccat cggtgacgtg gtcgatccca acactcgcac
    12301 catcaaagtg cgcgcgtggg tcgataaccg ggatcagcga ctgaagccgg aaatgttcgc
    12361 acggctccgg ttggatatcg gagatgccac cccgtttttg acgattccca aggaggcggt
    12421 tgtcgagatc gacgggaaac atttcgtcta tgtcgtggac ggggccgatc actactcgaa
    12481 gcatgaagtg accgtctcga atgtctccag cgggcaggta cgcatcctgg agggcctcac
    12541 atcgggccag cgcatcgtga ccaaaggcgc agtcctggta aaagggcagg aggtgaaagg
    12601 atgatcaggc cggtgatcgt gcgccactgc cgacaacagc gctctgaagc cacatgatgg
    12661 ttcgaattgt cgaactgtct ctggtccagc ggtttctgat ctgtgcgctc ggcttcactc
    12721 ttctctttgg cgggttgtac gcctttcaac aactcgatat cgtggcctac cctgatccct
    12781 cgcccccgat ggtggaggtg atcacccaat ttcccgggtg gtccgcggaa gagatcgagc
    12841 gccagattac gattcccatt gaggtcgcgc tcaatggcat gccggggctc accgatatcc
    12901 gctcactgtc gattttcgga ttgagcgata tcaaaatcta tttcgatttc aacacccagt
    12961 actttttcga ccgccaggaa gtcgtcaacc gcctctcgac gctcagcctt ccgcaaaatg
    13021 ttcaaccggc tctatcgccc tggtgggcca ttgccgaaat ctatcggtat caactggagg
    13081 gggacgggaa ggcgagcctg accgacctca agactatcca ggactggcaa ttgcggcgag
    13141 agttccggcg cgtacccggg atcatcgatg tgacggcctt cggcggaacg acgcaggagt
    13201 atcacgttga tgtcgatccg ggaaaactca tcagctacca ggtcagcctt gcgcaggtca
    13261 tggaggcctt gaccaacagc aatgccaatg tcggcgggaa ttacctgacc gtgggcgcac
    13321 aaaattacaa catccgcgga ctcgggctga tcaacgggct ggcggacatc gaaaacgtga
    13381 tggtcgccga aaaagaaggg accccgattt tcatcaagac cctggggagc gtgtcggtcg
    13441 gccatcgcgt gcgcctgggc aaggtcggca tcgatgacaa tgacgacgtg gtggaagggg
    13501 tcattctgct ccagcgaggg tataaggcac tctcggtcct ggatcgcgtt cgggaaaagg
    13561 tcgaggagtt gaataagtgg aagctgccgg aaggcgtcaa gatcaagacg ttctatgatc
    13621 gcacggcact gatccatacg acggtcgaga ccgtcacgga tattctgatc agcggcatgg
    13681 tcctcgtgtt tatcatcctc ttcgtgttcc tggggcattt gcgcgcctct ctcattgtcg
    13741 cgctgaccat tccgatgtcc ctgctgttca cctttacgat gatggtgatg atcgggcagt
    13801 ccgccaactt gatttccctg ggcgccatcg atttcgggat catcgtggat gcgaccctgg
    13861 tcatggtgga aagcatcttt ttccatctgg gacatgatcg ccgcctgggt ctgacggtgc
    13921 cacagcagat cgtgcgtgcc gcccgccagg tggggcagcc gattttcttt tctaccgcca
    13981 tcatcgtggt ggccttcatt cccctgttca cgatgaccgg cgtgccggga aaaatctttg
    14041 cgccgatgtc gatcacctat ggattcgctt tgttcggcgc cttactcatg gcctttacgc
    14101 tagcccctgt cctatgctcg ttgctcctga ccggtgtggt gacggaacag gacacgcgtt
    14161 tcgtcagcgc gattcgccgg acgtacctgg ccgtcctgcg atgggcgctg gctcacaata
    14221 tgaaggtcat cggtgctgcg ttgctgctgt tggtggcggc gttcggtgcc ctgcagttca
    14281 tcggcgggga attcatgccc gcattggagg aagggaacct ctgggtgcgg gccaccatgc
    14341 cggtggatat ttcgttcgac gaagcggctc gattgaccgg agaaatccgg cagatgttca
    14401 ggaaatcgcc ggaagtcgtc acgatcgtct cgcaactcgg cagacccgac gacggcaccg
    14461 atcccaccag ttttttcaat gcggaatttc tggccaatct caaaccacat aaggactggc
    14521 ggacgggact caccaaagat cagctggtgg aggaaatcga agaacgcctc aaggtcattc
    14581 ccggcatcat ttttaatttc tcccaggtga ttcaggacaa tgtggaagaa gcgatgtccg
    14641 gcgtaaaagg cgaaaattcc atcaagctgt tcggcaccga tctgaaaacg atggaagcga
    14701 aggcgggaga aatcgagtcg gtgatgagag gcgttcacgg ggtcaaagat ttagggattt
    14761 tccgcctggt gggccaaccc aatcttttga tccaagttga tcgggaagcc agcgcgcggt
    14821 atggcctgcg cgtgtccgac gtcaacgccg tcgtgcaggc ggcggtgggg gggcaggccg
    14881 tgacgcaagt gttcgaaggg gagcggttgt tcgatttagt tgtccgcttt ctccccgaat
    14941 ttcggcggga tgaggaggcc atcggtaata ttctggtcaa tacgccgaat ggcgcgcgca
    15001 ttcccctgaa acaggtggcg acgatcaaga ctcagaccgg agccttcatc atctatcggg
    15061 agaacaatga acggtatatt ccgatcaagt tcagcgtgcg cgagcgcgac ctggaaagca
    15121 ccgtgaaaga ggcgcaagcg aaaatggctc aggctgtctc gcttcccgag cgctaccgga
    15181 tcgaatgggc gggccaatac gatcaactca cggcagagca aaagcgcctc acgatgattg
    15241 tgccgttgag cctggtgatc atcctctttc tgctctatac cacattcaat tcgctgacca
    15301 acgccttgct cgtcctggtg accgttccct tcgcgctgat cggagggatt ttttcactgg
    15361 tgttcacggg aacgcacttc agcatctctg cggccgtggg agtcatctcg acgctgggag
    15421 tagcgattct cgggggagtc ctgttaatct cccgtattga ggattttcgg cgcagcggcc
    15481 tggaattgcg tgaggccatt ttgaagggcg cggatgttca gatgcgtccg atcctgatgg
    15541 ccacgctggc ggcagccatc ggcttgcttc cggccgcact ggcgacgggg atcggctcgc
    15601 aggcacagca acccctcgcg cgggtcgtgg tgggaggaat gttgactgcg gcggcgctga
    15661 ttctcgtggt gttgccggtc ttgtatgaag tggttcaccg gcgcacggcg ccgcgaacac
    15721 cgttggaagc cggagaggag ccaccggccc cttattaacg acaacgtgtg cgagaggatg
    15781 tgatcatgat cggagtcggg cagcagagga tgcgtcaagt ggtggtgctg ggtctgattc
    15841 ttcttggcct gatgggaatg cgcccagagg cgggctgggc tggcagcatg gtctggccgg
    15901 tgcaaatgcc gtatgaggcg ccgcccaagt cggaaccggt gcccgatgtg tcgatcgccc
    15961 ccaatacgaa ggccctgacg ccggaggaac tccagcgggc ggagtcgctc ttgccgctct
    16021 tggaaggaaa acaggaattt tgggccatgg gagaatttgt ccatttgggc gagcccgcgt
    16081 taccggtgct caccaaggcg ctcacaatgc ccggccctcg tatccggtac aatgccattg
    16141 agacgatgtc catgatcaag gccccggctg ccacgcccgc cttactcgaa gcggcaaaat
    16201 tggcgacgga aattccccgt atccgtgaac atgcgttgcg ggtggccgtg cggctcgatc
    16261 ctcagcaggc acctcccgcc atcgaggcta tggccaagga tcccaattcg gtgatccgca
    16321 aggcggcggc gttcgaggcc cggtatgtgc ggaaaaaaga agtgattcaa ccgttgatcg
    16381 atctgctggg ggatgaagaa aagtttgtcg cgatgtccgc cgtccaatcg ttatggacgt
    16441 tgacccggca tgagacagag tttcacgatt gggatgcctc caataaacag gatcggcaga
    16501 actgggcgca ggagtggatc gaatggtgga atcagtcaaa ggaaaccttt gaaattcctg
    16561 atccgaagac ccgcaagcag gccggctgac agaggaacgc acgaggcggt tgcacagcct
    16621 caaaagcccg tggtaggtac atacgcaggc aatagcggcg tgaccaaagt ggtcgcgcgt
    16681 aggcagataa aggtggatca tggccatatt ggcaatcagt aaactgggga atccgattct
    16741 tcgacagcag gcacagtcgg tctccccgag cgagataaaa aaggcagcct ttcagcagct
    16801 catcgacgac atgtttgaaa ccatgtatga cgaacccggc atcggcctgg ccgccccgca
    16861 ggtcgggcgt tcgcagcaac tcgtggtcat ggattgtccc ggggaagggg gcttccccaa
    16921 gacggtgctc atcaacccga cgattcggtt ctacggccct gagcaggtgg agggctggga
    16981 aggatgtctg agcgtggacg ggttgcgggg caaggtgacc cggccgtcaa ccgtgcgtgt
    17041 gaccggattg gatcgcaacg gcaaaccgtt cgattttgaa gccagcggac tgtatgccgt
    17101 gtgtatccag catgagctcg atcatctcat cggcaagtta tttatcgacc gcatgaccga
    17161 tttctccacg ctgacgcaga tggatgagtt tcagaagtat tggcaaaagg aaccggccag
    17221 tgtcatctga tcccttccgg gtcgccgggt cgttgtgaac tcgctcctac gcgttctgtc
    17281 ctacctcaag ccgttccgaa tgctggcggt ggtgaccttt gtgtgcgcgg ggctcgccac
    17341 ggcgttggaa ctggtaccgc cgtatctcgt caaaatcgtc atcgacgatg tcatccaagc
    17401 caagcggcct gagatgctca tgtgggtatt aggcgccctg ttggggtcgt atatcctgcg
    17461 gaacctcatg agctcgatgc gggtacggtt caacaattta ctggagcaga aagcggtcca
    17521 tacgctgcgg atgcaggtat tcggggcctt gcaacggtta tccctgagtt acttcgaaaa
    17581 ccgctccacc ggcgagatca tgacccgtgt gaccagcgat accgaacatg tcgaacgcat
    17641 cttcgtcgac gggcttgaag ggttgctgac tgcctccctc accctgatcg gcattacgat
    17701 catgatgttt tttttgaatt ggaaattggc actgctgtcg ctcgtgccca ttccgattct
    17761 gattgtgtgt gccgcctggt tcacgaagcg ggtgcacaaa tactacgccg agatccgaaa
    17821 gagtgtggcg gacctcaatg cctacctgca agacgccctg tcgggcatca aggaaaccat
    17881 cggcttcaat caacatgagt acgaacggaa gcgttttgaa accctgagcc agacctacag
    17941 ccagaatagt ttgcgggcca tgtttctgtg gtcgtggtat tggccgggca tggtgttcgt
    18001 cggcagtacc ggcacagtcc tcattctctg gtatggagca gaagaagtga tggccggcaa
    18061 tttgacggtc ggccaactgg tcatgttcct gtcctatctc ggcttgtttt atacgccgat
    18121 caacgagatt cattcgctga accacatgct gcaacatgcc ctggcggcca gcgagcgcgt
    18181 gttcgaaatt ctcgacacca aagcggaggt cgaggatcgg cccggggccg tacggcctgt
    18241 cgaacggttg agaggcgccg tggaatatcg gcaggtagta ttcggctacc ggcaagaagg
    18301 cacggtctta tccgatgtga atctcaccgt cagacccggg gaacgaattg ccctggtagg
    18361 tcccagcggc gcaggcaaaa catccttgct gaagctgctg atgcggtttt acgatgtccg
    18421 cagcggggcg gtgttggtgg atggttatga tgtccgggac ctgccggtcg cgtttttgcg
    18481 ggggcagatc ggcctggtgc agcaagagcc ctttctcttt aacgggacgg tgcgacagaa
    18541 tattgtgtac agcgacctct cggccagcca tgagcgcgtc gaagcggcgg cccgcgcggc
    18601 acgggcccac gactttatca cccggctgcc agatgggtat gatagctgga tcggcgagcg
    18661 gggcgtcaaa ttgtcggtcg gacagaagca gcgggtctcc attgcccgtg tcctgctgaa
    18721 ggatccgccg atcattatct tcgatgaagc tacgtccaat atcgataccg agaccgaggt
    18781 caaaatccgt gaagcgctga acgatctgac aaagggacgt accaccttca ttattgcgca
    18841 ccgcctcgcg acgttgcatg acgtagaccg aattatcgtt gtggagcggg gcacgatcgt
    18901 ggaggagggc caccacgatg cgctcatgaa gcggggcggg gtgtatgcgg gactctatga
    18961 agcgcagttc aagatttagc aggctgttga gaaaacccgc cagcggcgtt ctcggccgca
    19021 cgtctccttg cgacgtaccc agagggtacg actcagtcgc cgggcggcct gcggcctggc
    19081 tggacggcct ttctgaacag cctgcgacgg cggagaagaa cgacgtattc tgaccagtta
    19141 cgaaggagcg acaggaaaaa catggtgctg atattcgaaa gtgatccgct cgataatgag
    19201 gatgcccggg ggcggtttta tcatgtgtgc cggggtcgaa ttgatcggac ggaaattacc
    19261 ttgcctcaag ggcaatcgat atatgagtgt gcggtatgcg ggattgatct ggaaccggaa
    19321 gatttctgga tcgcgaggca aaagggatcg gtgtgacggt tggtcgcacc gagtgacgat
    19381 agacagagga gtgcgttatg gctggaagta taggccggaa gactgtatcg gtttcacgcg
    19441 ggctgatgat gttgtgcgag acctgctacg atcaggtgta tgccgagaag ctgcctgatg
    19501 ccaggaactt tatcgcggat catgaggcgt tgttcgatac gatttgtatg ggttgcaccg
    19561 acatcaatcg tccgctcatc gacgatatgc tggggagttc ggagtagcgg tcttatatgc
    19621 tgaccgacag agcagtgtta ggcagcatca accggtcaaa tgggcctctc gctaaaaaat
    19681 gaactcgttg cgacagctag cgactcatgt gcacgaggtt attctgacac tcccatcggg
    19741 ccggtagctc gaattgagtc gtggttgatt cgctttccca gtgcgaaccc tgatcggttg
    19801 ccgcttggag ttttaagaaa gtcgtatacg gtgaagccac tcgtcgcgat caacggcgcc
    19861 tcgatgttcg gtgagctcgc gattgtatcc tgcttggaaa aggatggttg gacggcattt
    19921 tgggtggata catttcacgg acgaaagttc tggcgcggca tgccgcatgt gacccagcct
    19981 acggaaccac cgaccaaggt aaaagctctt tatgctcgta ttgctgatcg aaagggtggc
    20041 ccttcaggtt gttttgacat cgtcgcgtcg aaaggcgacc gcatcatatg gctagagtac
    20101 aaaggcccaa aagatacggc gaatcgaaac gagttgtgct ggatcgaggc agctcttgga
    20161 gcgggtgtcg ctgagtcttc cctctttttt gtcggctcag atcggcggcc aaaagcagta
    20221 gaacgtacga tctagcggac attgcagcta tatattcacg ttggctactg cggaccgcgg
    20281 tcgaatgttc ggaggtagct ccagacccga agttattcta cacgtacctg ctagtgtcca
    20341 cgagctactt acacgtcttt ccgtcgaagt gcaggcatgt tgattcgccg gatttcacct
    20401 tccaggtttt caggagcggg ggctggcctt cccgcgtctc cacgacgata tccaccaatc
    20461 ctgattgcnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnga gcgggggctg
    20581 gccttcccgc gtctccacga cgatatccac caatcctgat tgcggtagtt tctcgatgtg
    20641 agctttggct tcctccggca cgtccaccca gaacactgcg cccaaagtcg agatcagaat
    20701 gcggctgtta tcaacatcca cattgatgat ggggctgtag tagctctttt cagctgccga
    20761 ggacgtcccg ggatgtgtga ggccggtgag gcacaggatg agggcgatca taacgagcaa
    20821 taatcgcatc gaatactccc ttcgatgaca aggtcaaagc cggattatgg catcgttgct
    20881 gagcgattgg tagggggaac ctggtcgaac tgcaggcggg gagaccgtca catgatatgg
    20941 atatcggcgg gccggacttg gccgccggtg atccaatagg tgcgaatgtc tgctgcgggg
    21001 gcatgcatga gtgaaaccag cagataggcc ggaacaggca agttgatccg ttgccagatt
    21061 tcctcgtagt ccgtcgcgat tttgatgtcg gtgtgagacg gccgcgccgg atccttcgga
    21121 tgggaatgat agaccacttg caggtccaga ccgttcttgc gaatgtcttt tttagccgcg
    21181 gaaaagtcgc ccatatccat cacaaaggca atctccgccc gttcttccgg agagaggcgc
    21241 tccagatgcg cgaccttgtc ttcatcgaac gtagaaagtt tttccgcccc ctcgacagcc
    21301 acgatattcg tgatgcggta aaggtgcgtg acgactttgt tctttccggc taacagtccg
    21361 caacattcga acggagccag ttcgcgcgca tgcgcgacga tttgatccag aatgtgctgg
    21421 gggatcgaca gatcaggcat gtcagatggt gcaggccacg ctgtagtctc cgcccagatc
    21481 cttgatcgtc ggcgtcgcgc tgcacaaagg gcaacgcgga tctttcgggc gagagacctt
    21541 gcggaatttc atttccaagg catcgtagat caccagctta tccgcgatcg tttccccgat
    21601 gccgagaatt tccttgatgg cttctgatgc ctgcagaatg cccatggtac cggccagcac
    21661 acccagcacg ccggcttcct ggcagttcgg aaccaatcca gcgggaggcg gctcgggata
    21721 gaggcagcga taacagggga acccggcatg aggcttaatg ctcgtgagct ggccttcaaa
    21781 gcggaacatg ctggcggaga tcagcgtctt cttggcgaaa aagcatccat cgttcaccag
    21841 aaaccgcgtg gtgaaattat cggacccatc caagacgatg tcataatccg acaccaaccc
    21901 gagaatattc tccgtatcga cgttcagttg ataggtcttg atcgtaatgt cgggattgat
    21961 ggctgacagc atccgtcggc ccgattccac cttgggcacg ccgacggtcg cggtggtatg
    22021 caggatctgc cgctgaagat tggacaggtc gacgacatcg ccatcgacca gaccgatcgt
    22081 gccgatgcct gccgccgcca ggtacagggc ggcgggggaa ccgagtccgc cggcaccgat
    22141 caatagcacc ttggcttttg ccagtttgac ctgccctttg ccgcccactt cgttgaggat
    22201 aatgtgccgg ctgtagcgct gtatttgttg gtcggtaaat tccattcgac tcgtctcttg
    22261 tcgttcgtca gaggtgaatc cgccctctga ggtatggtct gaaagaaggc tgtagcctgg
    22321 ttattccacc acgttcagct caatcgggtc gacgacgcag cctttggtgc ggatgccgtc
    22381 gatggcccgt tcgatctctt cggtttcgcc ggtgagttcg aggtccatcc atccggtggt
    22441 ctcgcgcaca tcggcgcgtc gcacattggt gaccactctg aattcatgcc cgatctgata
    22501 gatgatcggt tccttgattt tattctcggg aaaacgaatg tgaaagcgta ggctggtcat
    22561 ggttatcctc cggcgatcgc gggaacgatc gatacttcat cgccgtcttt cagcgaggtc
    22621 tctttcccgt tcaggaagcg gatatcttcc tcattgacgt agatattcac gaagcgccgc
    22681 aaatcacctt tttcatcgca cagccggttc ttcaggcccg gataggtggc atcgagcgat
    22741 ccgatcatgt ccacaatgtt ggctgccgcg gattcaacct cgccctggcc cttcgtgagg
    22801 ggacgcaagg gtgttggaat acgaacctta atcatgattc accaccactg ttctttccca
    22861 ttttgaatgt tttttggaag ttcaccaggc tcggctggat ccggaacggc cgccccacgg
    22921 catccacgac cgcttcctga gtcttgaggc cgttacccgt aatgtacgcg acggtgacgt
    22981 cgttcttctt gatcagaccc tgcttgacga gtttgcacaa cacgccgatc gtcaccccgc
    23041 ctgccgtctc agcgaaaatg ccttcggtct gcgccagtaa cttgatccct tctaccactt
    23101 cttcgtccgt caccgcgtcc attgcgcctt tgctttcggc ggtagccttc agtgcgtagt
    23161 agccgtcagc cgggttgccg atggcgaggg atttggcgat ggtctttggc ttcaccggct
    23221 tgaagaagtc gcggccagcc ttgaaagccg tggcgatggg ggaacaccct tcggcctgcg
    23281 cgccgttgat cttggtacgc acctcatcga ccaggcccag tgccttcatt tcgtgcaggc
    23341 ccttccagat ctttgtcagc agggagcccg aggccatggg aatcacagcc tgatccggcg
    23401 tccgccagcc gagttgctcc accgtctcga aggccaacgt tttcgaccct tcggcatagt
    23461 agggacgaat attgatgttg acgaaggccc agccatgttc accggcgatt tcgctgcaga
    23521 gccggttgac atcatcgtag ttgccctcga cctcgaccac gttcggctta taaatcaggt
    23581 tgccgagaac cttggcggct tcgaggtcgg cagggatgaa gacataacac ttcatgcccg
    23641 ctgcggcggc atgagccgcg acggagttgg ccagattgcc tgtggaggcg caggctaccg
    23701 tctcaaaacc gagttcccgt gcgcgcgtga gggcgaccga gacgacccga tctttgaatg
    23761 acagggtcgg atgattgacc gtatcgttct tgatgtagag ctcgtcgatg cccagatgtg
    23821 cgccgagatt cttggcccgc accaagggtg tcagtcccgc atggggcccg atgatcgagg
    23881 tgctttcgac cggtaacagg tcgatgtagc gccacatgct gttcgggccc tgctcgattt
    23941 tcttgcgcga gatggtgctc ttgatctcat cgtagttgta tttcacttcc agcgggccga
    24001 agcacatctc acagacatgg atggctttgg gtggatattc cttcccacat tcccggcaca
    24061 cgagcgcttt cattttcgac atggagacac cttcgctaca agttacgttg acccggaagc
    24121 gcacatgtcg gcccaccgac gtcgccgtct tcaatcagct ccgtaatcgt gggccgctcc
    24181 ccgcatagcg ggcaatcggg gttccgcttg atgcggattt ctctgaactg cgtgcgtcgc
    24241 gcatcaaaat ccagcagccg atcggtcagc gggcggccga tgcccaggat cagcttgagc
    24301 gcttcagttg cttgaatcgt tccgataata ccggccaaca cgccgatgac gcctgcttcc
    24361 tggcaggagg cgacgagtcc ttcgggcggt ggcttcttaa agacgcatcg ataacaggcc
    24421 gactttttcg gaatgatggt ggtcacgcgc ccgtcgaacc ggagaatgcc gccgtgcacc
    24481 agcggtttgc cggcgaaata gcaggcatcg ttgatgagaa acttcgtcgg gaaattatcg
    24541 acgccgtcga tgaccacatc gtaaccgctc atgatcttga gggcgttgcc tgccgtgagc
    24601 cgctcttcgt acatcaccac gttcacgtcg ggattcagcg cttggatctt ctctttgccg
    24661 gagacgactt tggggcgccc gacgtccggt gtctggtgaa tgacctgacg ctgtagattg
    24721 ctgagatcca ccacatcgct atcgatcagc ccgattgtgc cgatgccggc ggcagccaga
    24781 tataaggctg ccggcgaacc aagaccacca gccccgacga tgagaacctt gccctggatg
    24841 atcttctttt ggcccttgcc gccgacttca ggcaacagga tgtggcggct gtagcggttg
    24901 atttgtgttt ctgtaaattc catgtccgac ggaggctgaa aaccgtcacc agcggcgttc
    24961 tcgcatcatt caggccctca acgtaccgca agggtacgcc tcggcccttc attcgctgcg
    25021 gccttgctgg atgacgcttt tgagcctcct ctccctaaat ggtctgccgt acgctcaaat
    25081 attgaaatac ttttctatac tgatataccg ctcgccggtg tcgcaaagaa tcgtgacgac
    25141 atttttgccg ggacccaatt cctcagcgat cttctgggcg gcgaagacgt tggcgccggc
    25201 ggaaataccg accagcagcc cttctttctt ggcgagcaat ttggccgttt gataggcttc
    25261 atcgtcggtc acagtaatca cgcggtccag caaggtacgg ttcaacactt tgggcacgaa
    25321 ccccgcaccg atcccttgaa tcttatgcgg tcccggatct ccacccgaca gcaccggtga
    25381 gccggccggt tccaccgcca cgattttcgc cgccggattc cgctcccgga tcacttctcc
    25441 gcaaccggtg atcgttccgc cggtcccgac ggccgccacg aacgcatcga cccgaccatc
    25501 cagcgcctcc acaatttccg gaccggtggt tttacgatgc atggctggat tcgcgggatt
    25561 ggagaactgg tcgggcatat agtacgacgg attctgcgcg acgatgcttt ccgcttcctt
    25621 gatagagccc ttcatccctt cccaggccgc cgtgagaacc agttgtgcgc cataggagga
    25681 caacaggctc gcacgttcca tgctcatgct ttccggcatg actaaaatca atttataccc
    25741 acgaaccgcg gccaccaatg cgaggccgat gccggtgttg ccgctcgtcg gttcgacaat
    25801 ggtcccgcct ggcttcagtt tgccctgccg ctccgcctcg ttgatcatgt tgaggcaaat
    25861 gcgatccttg atgctcccgc ccgggttgaa cgattcgact ttcgcgtaga tcgtcgccga
    25921 gcctggtttg gtcaaccgat tgagccgcac cagcggggtg cctccgatca actcggtgat
    25981 gtctccgtgg gccttcgcgg tcaccggcca ccgcccatgt agaagagaaa ttccacatga
    26041 tcgccatctt tcagctgagt ggtctcgaga tgtgtccgtt ccagcatggt gtcgttcact
    26101 tcaaccgcaa ccatttgcgg ttcgatgctc tttgctttca gcaggtcgag gaccgtgccg
    26161 cctgcgatct cttccgcttt gccgttgatc atcacctgca tatctgctcc tgagatggta
    26221 agagtctgac aggatactga acatgtccgc cagcggttct cgcatctctc aggtcctcaa
    26281 cgtaccgcga gggtacgctt cgtcccttcg tttgctgcgg ccttgctgga aggccatgtt
    26341 gagtatcctg tcgaaaggga ttctggttgc gccttacacg ccgttgctcg gtgttcaatg
    26401 agctcgacgc gatttgcagc aaactgctaa agaatttcaa gaagttagca aacgcgttct
    26461 tgtgttgtca aggcaacgga cccccaacgg gtgcgacgag gaagttgctg cgaagtcgtc
    26521 tggtagagac ggccgctttc ttgactttca ccatgcctag cttacagtat gcgccggtct
    26581 ggagggtagg gtatgtggaa gaaaaatttc ttattccgtg cgcatgaagc ggctccgctc
    26641 aaagaatcgg aaaacgagct gttccatgac gacgctgaac cggccttgga cagcgccggc
    26701 ctacaaatgg aaaagtttct ctcggtgtgg gtgcagggag aaggcgaaga cgaaaagccc
    26761 accatgtata cgaacatgta tgtgcgtacg gctacgctcg attttaaaac ccgggcggga
    26821 tttctccagc ctctgcaggg acgcacacat cagatcaagc agatgttgac gccggagcag
    26881 aagggatttc tacgcgagtg gttgtccacg acctcacctc aagcctggga agactccgac
    26941 gaccattttc gaaccctctt tgatctcgag tgatccattc aatcaggatg ctgaagacct
    27001 ccgccagcgg cgttccctca tcattcagat cctcaacgta ccgcaagggt acgctccgga
    27061 tcttcattcg ctgcggcttt gctggacgaa cgttttgaac ctcctgtgga aatctttcta
    27121 tggttcatat gcaagggatc acagtgcgcg agtgtgtacc gtctctcttc atccagctag
    27181 accacgcatg agtcatccca catctcttcc tctgatggcc ctgattgtgg ccgggttcat
    27241 gtttctgtcg cagggaccgg tctgtgcctc cgccacgatt gaggtctact atgctcccga
    27301 agatcacccc attgatcatg tggtgaatct gtatggccgg gcgaccagat acatttacgt
    27361 ctcggtgtac gggctgacgg ctccctctat cgtgaaagca ctggtggagg cgaaacatcg
    27421 cggcgtcgat gtgcgagtga ttaccgatcg agaacgtctc actgatccga agcagcatag
    27481 cgccgtgaag acattgcgac tcgcgggcgt gcccgtccgg atcaaccggc atgatgcctt
    27541 gatgcatctc aagcaggtgg tgatcgacga cgagatcaat acctccgggt cggcgaacca
    27601 cacgacgagc ggcaaccggt acaatgatga gcgactcgat gtcatcaccg atgcccggtt
    27661 gacggccaga gcgcgcgaga aatttttggc catgtggaat gaccgcgagc gattcgtcgt
    27721 ctggacagag taaggagtgg catggcacgt gccagcatag agacagatgt agcgattgtc
    27781 ggcgcgggcg gcggaggcgc cgtgttggca ttgatgctcg cgcaacaggg ggtacgctcc
    27841 gtggtgttgg aacgggcttc tggtccgccg caaggtctgc gcggggaaat tctgcagccc
    27901 aatggccagc gggtgctcga tcgtctaggg ttgctcgaca agctgccggc gcatgccgtg
    27961 cgatcggtgc atcgattcaa cttctgtcga tccggcggcg aacggctgtg cacggtcgat
    28021 tacagtgacc ttccggctcc ttacaatcgc gctgtggtga cgctgcccaa tgtcgcgcat
    28081 catgcgatcc tcgatgcgtt ggaaaagcag aatcccggcg ggctctggta cgatgccacc
    28141 tttaccgggc ttcgtttcga cggcagccgt gtcgtcggtc tgcaggcgac ccgtcatggg
    28201 gagccggttg aggtgtcttc gcgtttggta gtcggggccg acggtgcatt ctccaaggtt
    28261 cgcgagtcac tcggtatctc ggcggacatt catcggtatc cggaaagtta tctcattgcc
    28321 atactcaaag ctccgacggg gttcgatgag gcacggtatc tggtgggcaa acgtgaaatt
    28381 ctgggactat ttcccgctgc cggccaacag gtctacgcat tctatatgat caaggccgga
    28441 tcgtatgacg ccgtgaaggc tcaaggactt gagtcgttac gacgggcttg ggtccggatc
    28501 gaccctgcca tggaatccat cgtctcaggt ttggtcgatt ggaatcagac cggctatatg
    28561 ccgaccgggc gtgttcgaac cgatcggtgg gtggcagatg gcgcggtgct catcggcgat
    28621 gcggctcatg ccatgaatcc ccatgcatct caaggccgca tgcaggcgat ggtggatgcg
    28681 gtgacggtgg ccgatctcat tcccggctgg ctcaagaaca atacgttttc gagtgaagcg
    28741 ttgcgcgcct tcgaagttgc ccggcggccg caggtgagca tgttgcaacg tctggcagac
    28801 gagcagtgtc gattctggaa caccgggaac ccgctgcttg ccttcctgcg cgatcgagtg
    28861 tttcgtacgc tcgaccgtaa tgcgcgcctc cggtatcgtg tgctgacgac caccgccgga
    28921 ctgcgaagcc agcctccgtt ttcgatgctc gatcgcgtga tggctgcggg gttgttgcca
    28981 gacccctctg cggatcggaa atcatcggtc ggaacataga agaagatggt ccttgtaggc
    29041 cacgagagtt tcatcagagt aagaatgaat tgtcccgggg catgttcaaa aagtcgtcca
    29101 gcaaggccgc agccaagcga agagctgagg cgtacccttg tggtacgttg aggctccgaa
    29161 cgaggcgaga gcgccactgg aagacttttc agcatcctac ccaactacag ccgaggtgtt
    29221 tgtgactcaa ccgaccgcgc tcgatgtccc ctccgaggtg caacaactcc tgcagcgata
    29281 cgtcaaggaa acgaccactc tgctcggtcc gcaactggag gggattctcc tgtacgggag
    29341 cgcggtaggc ggggagtttt tgccgggtcg ttcaaatctc aatcttttgc tgatgctttc
    29401 cggctatgac cgggaaggga tgaaacggta cgccaaagcc cataagcgct ggagccgtga
    29461 acaattcgtc gtgccgctcc tggtgacgga gaccgaattg accaaacccg gcaccgtttt
    29521 cccactcgaa tatctggaaa tacaggagca acatcgcgtg ctctggggga aggatccgtt
    29581 tatcggcctc catatcgatc gcacacattt agcgtatcag gtacagcagg gtattcaggg
    29641 caatctggtg cgattgcggc agcggtttat cgagggcggc gggacggagg aagcgacgac
    29701 gatgttattg ccgctgtcgt tgacggcctt attgccctgt ttgcgcgggt tgcagcgcct
    29761 ggccggacac ccggcgttat ttcaatcgga cgcgttgctc acggccattc gccacatgac
    29821 gggactcgat ttagcaggac tcggtgatgt gttggaattg aagcgcggga tcatttcgcc
    29881 cggaccggtg gaagtcccgc gcttatacga gcgctatgcc ggaaatctcg aagccttgat
    29941 cgccttgatc aggccggatg gcacggtggc gccgcgatga agaagcgctc actcacgatc
    30001 aacggactca tcccggcgct ctggctgctg tgtgtagtga tggcggcacc gttgggccat
    30061 gcgcgggaac cggttccgaa ctatgatccc caagggtatg tcagtgacca tgcaggcgtc
    30121 atcgaagcgg actggcgcgc cagaattcgg tccgtctgcc aggaccttga acgaaagacc
    30181 ggcgtggaaa tggtggtggt gactgtcccg acgctgaagc cctatccctc agccaacgat
    30241 tatgcgatgg gcctctatca aaaatggggc atcggctccg cccaggatga acatggggtg
    30301 ttgatcctgt tggccgtgca ggaacgccag gcggccgtga ccatggggcg gcgcatgatc
    30361 ccggtgatgg gcggggaggt ggtcggcaag gtcggacatg agtatctcga ccccgcgatt
    30421 aagaacgggc atttcgacga agggctgtat cgcacggtag tcgccttggc ctctgtctcg
    30481 caggagatcc gcgtcggctc cacgaagaag gcgcattttc gcggactggg cttctggatc
    30541 accgtcacca cggcgagcgg agccctctgg tttttgtggt ggctgagccg cccggatttg
    30601 cggcacccct ttggccgcat ccgaaaggga caatactggg ggaccggaca gggtggattc
    30661 ggcggcaact tcggcggcat gggtggcgga atgagcgggg agggatggaa gtagggagga
    30721 gggtggcccg ttggtctccc ttgctcgcgc aacgcgcggt cgaagactcc cctcgtccga
    30781 cgcgcgcagt gggagcccaa tccagtccac ctcaggcttg atgcgacatg aacgaagaga
    30841 cggctggctg tcgctttatc cctgcagttg cgtcatcatg gtggctggat tccagtagcc
    30901 ccacatggtt tggatttttc cttcctgatt aatctcgaac acatcgatac cctcgaagaa
    30961 aaccggccga ccgtttttgc cggtaccccg tcccgtgaat ttaacggcga ctctgttcgc
    31021 agactggaat acgtggtcag ctgtcatcct gatggtttca aaggcaccga gcaccccgac
    31081 tagaaattgt cgcaacgccg cacgtccctt tagcggagcc ggcgctcctg gttcataact
    31141 gataccttcc tcggcgaagc agctgaccca cgaatctgca tccatcttcc caatggcctc
    31201 aaagtattgc cgcaccgccg caggaatcgt ctcgtccttc atcgtttttt ctcctctccc
    31261 tcataggccc ggtcatatcc ggcgaatttt caagcgctgt tcatactacg aaggaattcg
    31321 cccgttggat tgaaatcgat gagtgcaaat ggacggggtg tgacgaacga caaggcggga
    31381 accagttggt tccgccacct ggattgtggc gtggctcgct tggcggtctg agcctattcc
    31441 atgacccaga gtgcgatgcc ggagagttcc cgagagagac gctctgcgac gttgttactg
    31501 aagaggtgcg cggcatccgg ttggctgtgc ttcgtgatca cgagggtgcc atagccgccc
    31561 gctcgtactt catcgagaat ggtgtcgacg agatcacctg cgtatcccaa tttgagcatc
    31621 acccgctcgg tgggaaagcc tgtgtccttg agtcgctcga gcgctctctc aaggatggga
    31681 tattcaaggg tctcctccat ctgcatccat tcttgctgat ctttgcgcag ttgttcgccg
    31741 agctgatgtt ccatgtcagg attttccgat cccccgtgtt ccatcaactc ccgcggcatg
    31801 gggttcaaca catgaaacaa ggtgatggcc acggacggcg tctcgcggag caatgctccg
    31861 acgtaatgga ggacacggat ggtggcgttt gaatcgtcga cggcgatgag gatgtttttg
    31921 ggagagacgg agcggttcga agtgtggccc ggggcgaagc gggattggtc atgcggcgca
    31981 gttgtggtca tgatgtcacc atacctgggt tggtgcgtgc cggtcctgtg gctgtgacca
    32041 tctttgaggg agaggctggt tctgtggccc gaagaggctt catggtgccc tcagagagac
    32101 gggctggagc gcgaaccgta cggcacctgc tggggatgca cagggtccgc ataggcataa
    32161 gcctatgctt ctcctgccaa caaatcaatc acgagcgcgg agtgagagaa agcgggagat
    32221 ccgcgctcct gcgtgatcgc gtgcgtccca tgaagccggg gaattggctt catgggacgg
    32281 gaacgaggga tggaatcagg acttcttctt ggctcgaggt gttttgacag tcttggccga
    32341 ttttccacgg gcaacgacac cgacgggcat gacgcgattg cgtatcaggt atgacgcgat
    32401 ttcaggcgcc cggttgccgg caggtcctgc cggattgctg tccgcatagg agctcggagg
    32461 attatgtttg aacagccaga gttgtacgac gctcatgggc gtcatcggtg cggggatacc
    32521 ggttccacga aacttcatca tcccctgcgt ttgaacgagg actgatccgc tggcgaccga
    32581 cggatacaac gcgacgccgc ccatgagttc aatgagggtt tccatcgcga catgattgct
    32641 ctgcggaaag ggcacaactt gcgtgaggcc aaatttcgta atgccggcat gctggtgaag
    32701 caagctgatt tcttgtcccg tcgcatagcg aaagccgtag gtggtggtgt acccaccagc
    32761 gccgcccaag acgtccatat aggacaggtt tgccgtcgcg ttcagactga gccattcgag
    32821 attcgtctca gtgtcgagtg tgatcaagtg atcgccggtg ccgggaacca ggttctgttg
    32881 aacgagagcc atctacgtac ctcctggccg atggttggaa tgatggggta tcgcgattca
    32941 cgcatgtctt gtgccattcg cgtgccagaa tggattcgtg cgaatgcgcc ctgaacagac
    33001 cctggaatgg tgatgccagt acgaagtggc acgtatagcc gtgtactcgc ctcacataca
    33061 gaaccggagc gtatcatgag ggatacagtg aggaatctat tcggatacga ttaggagttc
    33121 ggtgccaaag aaggcaaggg tatgggagga gatcaatcca tgcgtggtga tcgattgact
    33181 gatcaaggca ctatcctctg cgaggaacgg gcctgccttc ctccaagtct tgaagatcag
    33241 accaggccgt aatgtcagtc cgcgaaggat ctatcgcgtc gcggtacttg gcaaatttcg
    33301 cagcactttc cggcgaactc ggaccgcgcc caagcaactt cccgttccag tcctcaagat
    33361 ccgctgctcg atgcggagtg gcggtgcgtc gaaaccactc cgccaccccg tcatcggtca
    33421 cattggtctt cacggcagcc gtgaactgct cggccgtaat gcccgcatat tccagcagcc
    33481 gttcatccat cgggcaggga taaatgtact ccccttcagt gccggccagc accgcgcggc
    33541 acttgtcgat catccgcgcc aggtggacat agccagccag cctggttttc atgctacggg
    33601 ggaatgtctt ccgcaaatcc atcaggccag caatttgtgg ttggtgaatg tcagggttcg
    33661 gacaaggacc gcgccgtttt catacgaaat gatgcgccgt gccgctggaa gatcagacgc
    33721 gccgatgcgc acatgtgtat ccgtaaagct ttcgacattg cgcaatgtgc tgtccttcgg
    33781 tgcgaaataa tatacggtgt acttcgtggt cagttgcttc tggtcctggg tggtgctgct
    33841 ctcttccaca ttgatggtga aggccacgtg cggcatcttc cggttgatct gggtaatccg
    33901 gttatccttg atgcgataga aggactgcat gccgtcgccg tgaatgtcga gccggcggcc
    33961 cagcggatgt ccctcgccgc tctccatcgt cagccggtgt tttccgtctg attcctcgaa
    34021 cttgcggggt gcgcggtgca cggcgatcat gccgatctgc tcctgcgccc atttctgaat
    34081 cgcttcatcg gggagttgga cgctcacctc ccgcggtccc ttgaccacga cggttccgct
    34141 cacgacctgc ccattggtgt tgacgctgag gtcggccgaa aaacctcgaa aatccggttg
    34201 ccaccgggcc gtattctcga aggcgcgttg aagaatggca cgtgcctgag gatcatcggc
    34261 aacggtcggt tgtgtatcaa cagcggcgac atgttccatc ggaggctcct ttgtgtcgtg
    34321 gaagggataa aaaataatta tagagacgtt gatcgatcat ctacaactgt ggaggacatg
    34381 atcttgcgca agaatcccgt tttgccggcc ggcaaaattt ctctcatttg accaaggttt
    34441 gtgtagtact ggctaggccg aatctgttat actgcggggc atttcatccg gcaatttgac
    34501 gaatgtgtga cagaagtttc ggcattcctt gaaaggagcg ctatggagcg gcgagcggcg
    34561 tctcatactg aagaagaaga aatgaaccaa cggcggaggc tgttgggact ggctcgcaag
    34621 ggcgacccca aagccatcag caagttgttc gagctatacc aagtgcgtgt gctgaacggc
    34681 gatatgctga gtaagctcaa taaatcctac tacaaggcgg cggctgcgca ggagcaaaag
    34741 gccgcacaga ctccggccaa gtccgcaaag ggctcgcaag cgactcacgg cagcgccaaa
    34801 gggagtgcca agaagtctgc cgcggcggct gcgccggcaa ccaaagcgaa acctacgaaa
    34861 gccgccacac cgaaaaaacg agcgaagtaa tttatctgtg tcgagagggt cggcgaagac
    34921 cgccggccct cttctcgaat catcttactg aacacccacc cgcaatcctc cggccgcaag
    34981 tttggttccg atttcttcag ccaccttccg ggctcctgaa tagaccgtgg cctggccttc
    35041 atggtcgatg cgccatgcca attcgaaggc ccgggaagag ttcattcctg gaatacactt
    35101 gcagaacagg gcaatgacct gctggtaggt gtggcattcg caattaaaca cgatcacgcg
    35161 ggcttccaga tcgtcgcccg tgcccacgtc ggtggtgtcg agggcgtcgg gggtcatgac
    35221 gggggtgagg gtactcatgc ggtcgtctcg ttcggcgccg agtgtaccag gtgacacggg
    35281 ggcgagtgca acaggttgtc agcctctctt gaccttcgct gccgcagacg tcggacaaat
    35341 atcttacttg gatagcgtga cgtcgtcatg gggctgcggg gctctgggat ggcacgacat
    35401 actcgttagg cagatcgatg ccctcccggg ccatggtgtg gctcagtaac cgatagtggg
    35461 tcttggaatc cgtcaccgga accaacccat gcgcgcgggc caggcgaaag gtgtagacct
    35521 gcgcggcggc ggttttcacg agcgcgagac catattcaaa ttggtaggcg tcctccagcg
    35581 ttgcggacga acgtgccaag tgtttcacca gccccacggt acacacttcg gtagcgcgtt
    35641 gcggttcgag aagccgaagc agggcggccg gccccggcac gagagttgat ccaatccgca
    35701 tggcatgggt cagatcaaac aggccacgtt gaaaccgtcg atctgcctgc aatccggcat
    35761 ggaatagccc tctccaagca ggatcagaaa aatcacgatc gatctcggct acggcggtgt
    35821 catccagggg gccgctgacc gcatagccct gtacgatgcg accgttgctg acgaggtccg
    35881 gatgctcgtc tcccatgcga tcctgatagg ctgtggttcc catgaatggt gtaagccgga
    35941 gcgccatgta gtcgcgaaag tggagcgatc catagtgctc gagcaggtat tccagcgtgc
    36001 ccggggcgca gagatgaaac ggataaaaca gggcgtgacg acggggcaag gaagtcatac
    36061 gatgggctta tccagtgact gggatatcga ctcggagaga ggcctgcaaa tgaagatcga
    36121 agcgatgatt tgtgcgaaga aggttaccag ctatccatat cgatgacttc ggtcgcgtcc
    36181 cacaaatttt tcaactcagc ttccgcgatc gctttttcgc gatccgcttc cgtgtcctca
    36241 ccgaatcgtt tgggctgagt cgtctctgaa tcggcggcgg atgcagtgga ttcaaccggc
    36301 tggcgacggc ggcgtttact gggatccata ttgacgggca tgggaagaag tctccttttt
    36361 catttcagtc tcccctgtgt cggggaggga agtcaatggg ataggcgagg ctcactactc
    36421 atccaggctc gtcagaagag acaccgccac cgtatcggca taccgtctgc cccttgtggt
    36481 gaggcgaacc aggtcgccct tgcgttcgag taactcgtcc gccagcaatt tgtccacttc
    36541 ccgtgagagc tcaggaaatg agagggctcc ggtctgtgta agggaaatgc catcaacgag
    36601 gcgcaaccca aagatgagtc gttcgcagct ttcgcccgcc tgcgtcagct gatcggattc
    36661 cgacacaggg agacgaccat tcctcagggc tgccttgtag gctgtcagat cgctcacatt
    36721 gccgaatcgc cgacctccaa tataggactg cgcactgggg ccgacgccaa ggtaatgccc
    36781 gccggtccag tgcaggcggt tgtgtctgct ggcacatcca ggtcggcaat agttggaaat
    36841 ttcgtagcga tcgtaaccgg ctcgtcccaa aatttcttcg gcgaggtcct ccattcggtt
    36901 ttgaagctct tcgtcggggg cggggaggag gccgcgctga atagatgact tgaggtgagt
    36961 gccttcctca atggttaggg cgtaacacga caggtgttca ggcgccagct cgatagtctg
    37021 ccgtaacgag gtggcccaac tctccagcgt ctggcccggg agtccgtaca tgagatcgag
    37081 attgatgttg gtgaagccgg cttcgcgagc catggccatg acatggagag tggtgctggg
    37141 agagcccggg cgtccgacgc gatcgagctc cgtttgatcc atcgattcgg ctccaaagct
    37201 caggcgtgtg catccggctt ccctgaggtg cgccaggctg tcccgtgaaa ccgatccggg
    37261 atgggcttca atggtgacct cggcgtccgg agccagtccg aacacttgcg cacttgttgc
    37321 gaggagtgtc gcgagttgct gggaggagag cgttgtgggc gtcccgccgc cgaaatagat
    37381 ggaatccagt ggatcctgtc tcaatacgcc gctctcgccg tacacacgca cttccgtcaa
    37441 cagcgccgag acaaattctt ccgcagcgcg cgcctggtga atttccaggt aaaaagcgca
    37501 gaaatgacag cgctggtgac agaagggaat gtgaatgtag agaccctgag cggtcgcctg
    37561 ggacatagcc ggctcgtgtg cctatggagt tggtgaaaag tcgcggatca tggcgacttc
    37621 aatttcttcc gtcggggatt ttccccggtt tctgacatgc gatttccagg cggggtattc
    37681 ccgcagcgtg tcaaacaggt tcttgatcag gaccggcttg atctgcagtt cccactcacg
    37741 cagccaggcc tgctcatcga gtgggccgtc gtagtcgtcg gggaattgcg cttccaggct
    37801 gatgcgaaat acaaaggatt tatcttctga ccacatgtgt ggactcctgt cggctgtgat
    37861 tgcgaaagtg aattggcctt acttataata tttcaaaatc caaggagtac agcccatgcc
    37921 catcttcgaa tacgtctgcc aggaatgcaa ccaccgcttc gagctcatcg tgcagggaca
    37981 gacggttccg gcctgtcctt cctgcaaggg gacgacgttg aataaacaat tttccgcctt
    38041 cggcgtgggg gcaacaggcg gatggccggt cgtctcgaat tccggcggcg gctgcggctc
    38101 ctgcggagat ccgcggggtc ccggcgcctg ctccatgaat tagcacgacg cgacctcatt
    38161 cgagttattc atgatgaacg atcaagaaga acaattgcgt cgcgcgatcg gcacgctgct
    38221 ccagtcagac ccgttgatca aattgttgca ggaagtccgg ctggggcgga tgaaagcgac
    38281 agacgccgga ttacgggcgg tcgttgaatc ctggatcggg acctacgcgc aggtcttgaa
    38341 gtctcaatct ctcaatgccg aactgctggc tcgactcgat ccggtgcccc gccttcaagt
    38401 gctggtggat gccggggtat tgtcttggga gcattctgcc acatgcgagc tcagggactt
    38461 atttcgcggc ctgctggtcc ctgctgcctg acgtgaggag tgcgctccag gtgcgtaccc
    38521 accttgccat ggccttgctg gtgctggcct ggttgatgcc ggctaccgtt tcggccgaaa
    38581 taccctctcc gctgcgtccg ttacatacga ccctgtccgc agcgctggcg acccttcctt
    38641 ctgacagcca tctccttctc gatcgtgaac ccatcgaaca gtttctcgcg gcgctggacg
    38701 ggtcgcctcc cgactggcct cagatctacg gtcaggggca tcatgatccc ggtcacgacg
    38761 aacggctgtt tgctttaaac cgtgaacgtg atgcccggcg cgaaggcaag gaacccttgc
    38821 aatggctagt gaccgtggtt tggcttggcg aagtatcacg gtttgacgaa gaagaggggg
    38881 gattccgtgt cgcgctgggg ccgaaattta atcggacggc atggggcgag gtacgtttca
    38941 aacatgaaga tcttccggcc acactgatcg cctcggcggg tggggcgacg gatgatctca
    39001 aggccagaat gcagcggggc gagcggatcg acattgacgt ggtgatgtgc ggcaggctga
    39061 ttcctgagga gtcactcgtc tacgattttt ctcacgaggt cgacggcctc ggcctcatca
    39121 tgccggttgt gcgtatcgaa gcggtggcat ttgtcctggc ggacggctcg cgataatggc
    39181 tggaatatcg tctggtagtt gagacgtgga acggctaggg tattcgcttt aggtggggat
    39241 aggcctgatg catgcaggat tcacagacag cttccttgac cgtgaagcgc gccagacggc
    39301 gtaagtagtc ctcgatccgt tgccaatagg atccatccgt cttcacacgc ttacacttgg
    39361 cgcaaatgtg aagagtgcca tggagcgtgg tcatttgctc gaaggcatgg tcgagttctt
    39421 tggtccgttc aagcagttcc tgttcacgta atttccgcgc atcaatttcc tgcttcaggc
    39481 tcaatgccgt ggcggctcgt gccagcaact cgaccggaat cacaggcttg cggatatagt
    39541 ccgtggcgcc ggccgtatac gcggcctgaa tatctttctc cgccgtatga gcggtaatga
    39601 tgatgatggg caaaccctga agctgttcct ccatcctgat tttctcgcag gcctccaatc
    39661 cattgatccc gggcatttcg aggtccatga ggacgagatc gatcccgttt ccgggctttc
    39721 cacgtttgcc gattcctaag agggtgagtc cttcttgtgc cgtcgcgacc ggaaggagtg
    39781 ggccgaatcc ggcacgatgc aggatagcgt ggaggaggtc tcgttcctcc tgaaaatcgt
    39841 cgatgataag aatgctcatg ctggcaagct ttctctacgg catcgcttaa acggcctgcc
    39901 tggcttgagt aagaagcgta gtcaggcggt cgatcgttcg gcgcatagcg gcgatgtcct
    39961 gctccctcgc tgcctgttcc agctgggctc ccgccagccc gatgtcgtgg aatccgtacg
    40021 agccggccag acctttgatg cggtgtccca tgatccggat ggcgtcgaag tctccttgct
    40081 cgatagcctc ctgcatgcgt ttcaggtcct gccggcgatg atcgaggaag aggggacggc
    40141 gtcgcgtaat ttcttcgtcg atcaacgctg ccatgcccgc gggcgagttg ttctgtgtca
    40201 cgactggttt ctttggagaa ggtcttgcgc caaacctccg gaatgcgtcc aggagctgtt
    40261 ctttgacaat gggcttggcc aagcatgccg tgcacccggc tgcttgggcc tgtgtcttca
    40321 cgtcgaccag tgagtcggcg gtcaaggtca gaatagggac tggcgcccgt tcattggatg
    40381 cttcccactc ccgcatcacg cgcgcggcgg taaaaccgtc catgaccggc atgtgttgat
    40441 ccagaaggac aagatcaaac tgttggctct ggaacatcgc gaccgcttct tttccattcc
    40501 ctaccacgtc aagctgatag gggaggcccc gaagatacag ttggatcaaa gcctgtgatt
    40561 cccgcgagtc atcggccagc aagacccggc atatcggttc agagccggtg tctgaggcac
    40621 gagaaagctg ggatgccata gccgacgctc gacggatcaa cgtgatgcgg acgtgacagt
    40681 acttagaagt agtatagcgg gtgaagcctg gacgacctag gatctcctga aaacccggca
    40741 ggtatgagga atcgatcgct cagagacctc gggcaggggc gaggctggag aaacagccct
    40801 tcgattagta gctatccctg gcgcaacgga atcccgtccc ggaagggcgg ctgtccatcg
    40861 tcccccaatc acgatcggag gtacgcaggc tgattgccgg tttgagccag gatccgccgc
    40921 gcatagcttt aatcgcgcca cgctctggtc cttggggatt cgtgagcgat gcggagcggt
    40981 aatggttggg gttataccag tcctgcaccc attcggcggc attgcctgcc atgtccagcg
    41041 ctccatacgg gctggcgccg ccaggaaaac tcccgaccgg cagcgtgagg atttccccct
    41101 tcagaccctt cgctttggag agttctgcgc ccaggccttt gatccagaac gcttcccact
    41161 ccctgctatc cgcaaactct acggttttcc cggcccagta gctcgcactg ttcgccttgt
    41221 cgaggctcca gtcgttgccc caggggtagg tccgtccgtc ggtcccccgg gcggcctttt
    41281 cccattccgc ttcggttggc aaccgtttgt tcgcccagcg gcagaatgcg acggcatcaa
    41341 gccaactcac attcacgacc ggatgctgct caatcccggg aagtggccgg ttctgttccc
    41401 atagagtcaa gcgatcggcg gcattggcgg gggcctgata gtttgtggcc tggacgaatt
    41461 gcagataggc ggcgttcgtg acctcgtacc gatcgatcaa gaacgacccg agatagacca
    41521 ggcgtatcgg ttgctcatcc gggaggccgc cccggtcaac ggaagctccc atcgtgaatt
    41581 cgccggcggg aaccagcacc atgtcgtcgg atgaaaggga tgcccaggct gcctgataca
    41641 gactgagcat gacgagcagg cagagcagaa accaccgagg ggtagccttc agcctcctca
    41701 tggcttcgtc agtttgcagg cttttgcgat gctgtcgcga taggccgccc acagcgtgag
    41761 cccttgcctc acgcaagcca gcacggcatt ctgctggctc ctcgtttcgg catagttgac
    41821 gaccatggtg tacgcgtcct ggcgatgccc cgcctcaacc ttctgatgcg cgcggatgag
    41881 atccatgtgc tcccgctcga tcttgtgatg acgaatgaga ggatgggcgt cgatataggc
    41941 ttcgatctgg gcctcggttt ttggcttgga gggttcctga atctcctgac ggtctttaat
    42001 actgccctcg acaaacaccg caagggcggc ggcgccgacc acccagtccc ggctggccgt
    42061 gaccttttcc agccaccgcc gatagcggag gctggctgga aggagggtgg ctcgcaggaa
    42121 gacccggctg tcgaacccca gcccgcgcat catttcgtta aatagctcgg gatgagatcg
    42181 cccgaaggac aggcccccgg tatcttcttc gtaaatgttc tcggccaaca tgcgccggac
    42241 gtcggggggc ggattctgcc catgcactcg agcgagcagg acagggaaat cccgcacgta
    42301 gaccaggtat tcctgttgat agtggagctt tagctgggcc ttagtgatcc cgggtcccat
    42361 gatgatcggc caggcccaat ggtgtttgcg atccatgatg gacaggagcc gctcgaggaa
    42421 ttgcgcacgg gtcaatctct tctgtgccat gccttgcctt ccttcgttcc tactggctac
    42481 aatcagccac cggtcagatg aagcctatca cgattcagga ttccgacgag attctcaact
    42541 tccttgccga ggttgccctg catggaaaag ggtttaccac ggactgtctg ttggactatg
    42601 tgctggaaga agggtttacg gagccgattt acctcaatgc ctccggtgaa gacccggacg
    42661 cattctataa gaatcagccg caggcctggg ccatttacca agttcgtgaa tggaaacgtg
    42721 ttctgaccgt gtcgggcggg cccgggaagg aacggcgcgt tcagattacc gagaccccgt
    42781 aagttgtccg ttgcccccct tcggccagga catcaacgcc gatctccgcg cagtcattgc
    42841 tccatatcca aggccagctt ctgcttccgg acgcggtgtg cgcttccgtg agtgtattga
    42901 ccatccgaag gaattgcaac gaatcacgcg ctgttcgcag tccggggcgc ctggtcctgt
    42961 ccattccgtt tggtaaatgt gcaagggtgt ctggcgagag gccattgtga cattacggca
    43021 tcatcctagg aatcttcagc ctctggtgag cctctgcgaa ccggcagatg tgggtgaatt
    43081 ggccctgatc cggagcctgc tcgacggcaa tggcattccc tacgccattc agcatgaaca
    43141 catcggcgca ctctatcccg gggtggcgct cttgggcagc cgcgttatgg tgtcggaatg
    43201 tgacaggcaa cgggcggaga ttctgttgag ccgcctggcc ctgcaggtcc gtgaggccac
    43261 cagcgagacg gattgaaacg ggatcaggtg gtcctggccc ggagtggtcg ttaggtgagg
    43321 cttacgggtg gcctttgggt ttgaccggtt ctggagtggt gggcaggggc aggcgcacgt
    43381 cggatcctga aaaatggccg ccgatcaact tgccctcttc aaagtagaga tagcggtgct
    43441 tgacgaccgc cgggctttcc caatcttcaa agatccattc ttcgcgccgt agcccatcgc
    43501 tggtatgggt gacgttcatc gtgttcggcg acccccacga atccaggacc tgtttgcgat
    43561 ccatccccac catcacgcga tggctttcga tatgtttgga gaaatccggg tccagccacc
    43621 cgggcacgaa gcgaaacgcg atcaaggcga ccacgaacag cgccaggaac gaattaatga
    43681 tgatcctgac cggccgctgg cggataaacg gtgttggctc cgctgtcggg ggtagggagg
    43741 aaacggggtc tgccgaagtc gtctgatcgg tcacaaatat ccttccatca acgagtgggc
    43801 gagtgcgaaa tgcctgctgc atgctaaaca ataggttttc ggtccgtcaa gggagggaat
    43861 caccctcaag aaagggcatt tcgccgcctg taccccggtt tcgacctgct atgcttaacg
    43921 gaggaccgaa ggagggcgaa aaatggggcg tggcggctgg aggcgggacc gggtgtgggc
    43981 gtgggtgact gcactgggcc tttgtctcct gggatatgca ggggttgatg ccgaggcggg
    44041 ctctctctac gtctatactg atgcccaggg ccaagccgtc ttgaccgaca atctcgacca
    44101 ggtaccggct gcctatcggg gacgggtgcg aaccatgact gatacggact cctcggctcc
    44161 tgctcctgga cccgcaccag caatcgccgg gaataagaca tctacgtcta cgtcctccgg
    44221 cgtgattggg gatatcctca gtgccgtggc ggcaaaagtt ggcgcgcgaa cgatcaaagg
    44281 gctgacggcc tatcaaacgg ccgtcgtgat tgtggcaggc gcttcttccc tgatcctgct
    44341 cttgtttatt tttttgagtg ccaatcctgc catcaggatt ctttgcaagg tgctgctggt
    44401 agtggtggga ctgtccgctc tctaccaggt cctggcgatc gatgcgccgt ccctggaggc
    44461 gcttgcggga cctcctcaac agggggcagg tcagccggtg gacaatatgt tgggacggat
    44521 gcgaagccag accgagcaga gttaccgcgc acagggtgaa cgcacggcca gccagttgga
    44581 gccacccgag caaccagctc cctgacacgc gtgctactca gcgtaagtgg gtaccggaat
    44641 ctttttcaca gcaggcgcgg gcggcggctg ctgtgagaag gccttggagt agggattcag
    44701 gaccggttcg tgggtgttgc gctggcgcag tttgaccaga ggcaggcttt gggtactgat
    44761 ttccaggcgg tcgatcagcg cttttgaggt cagcggatcc ggcagacctt gtaacgcgaa
    44821 catctggaag gcgagtgacc agtcgagtgc atcctttcct ttctcccgca caatgaaccg
    44881 cgcatcggcc gacgggctcc ccgaaaaaaa caacaacatg atgttggagc ggaacaccgg
    44941 cgcggaggcg tcctccgttg gtctgaattc aggaacgagt tgaggaatcc tgctcaaggc
    45001 caccggcgga gagaattcga tatcgacgag gcggacaaac aggggccgct gttcgttatg
    45061 atcgttggga tcaaacgtaa agctgaagga ataccggaca tcgatgccgt cccgcttgaa
    45121 ggtgtagaca tcttcgccgt tttcagggga gacgactttc ttgaagtatt gctcccagtc
    45181 gctgatgggg taataggtga agacgcgcaa ggcggatttg cggtcccgta cggcctgggg
    45241 cagcccgagt ttggcgtgta attcggtttg agtcagcccg agatagccat cctcaaaata
    45301 cgggccggcc cacagggaag ggcattccgg tccgaggagg ctgaagaaaa gaaggcaaca
    45361 aataatgagg cgggtgactg tctgatgcgc catacaatcg actcaggctc ggcccagaca
    45421 ctgtgtggca tcgtatcggc cggggtagtc attgtcaagg cggagagccc gtcatggctt
    45481 gctgaaaaaa gtccgttccc gatatgatgc ccgctcaatg gcagtcatcg cccgagtcgc
    45541 cgcacgcctg aagtcggcga cagaaagaca taggtagtca tgccggtaca cgatattcga
    45601 gagctgctcc gtgaacgtat cctgatcctc gacggggcca tggggaccat gatccagcgt
    45661 cataaactgg acgaagccgc gtttcgcggg gagcggttca aggattggaa aaaagacctc
    45721 aagggacaca acgacctgtt gaacgtcact caaccgagtg tgattgaggc aatccatcgg
    45781 cagtatctcg aagccggggc ggacattgtc gaaaccaata ccttcaattc tcaatccgtg
    45841 tcactggccg actacggaat ggaagatctt ggctatgagt tgtccaaagc cggagcggaa
    45901 tgtgccaagc gggcggtcgc tcaggtcgtg aaggcgcagc ctgcgcggcg ctgtttcgtg
    45961 gcgggcgcga tcgggccgac cacaaagacc tcgtcagtgt cgacagactc caatgacgcg
    46021 gcagcacgcg ggaccacgta tccggaattg gtgcaggcct atggcgagca ggtacgcggt
    46081 ctgctggacg gcggcgtcga cctgctgctc gtcgaaacga tcttcgacac gctgaatgcg
    46141 aaggcggctt tttttgcgat tcagcaactc ttcgcagaag gtgcccggca ggtcccgatc
    46201 atggcgtcgg tcacgtttat ccaagccggg agcaatcgcg gcttctcggg acagacggtt
    46261 gaagggttct ggaattctat ttcgcatgtg ccgctgctga gtgtgggcat gaactgcgcg
    46321 ctgggcccga aggaaatgcg gcccttgatc gaagagctgt cgcagctcgc gccgattttt
    46381 gtcagcagcc atccgaatgc cggcttgccc aatccgttgt taccgacggg ctttcccgaa
    46441 accccggagt cgctggcgcc tcagctgcgc gagtgggcac aaaacgggtg gcttaacatt
    46501 gtgggcggct gttgcgggac cacgcccgac catattcaca ctattgcgga agcggtgcgc
    46561 ggggtgtcac cccgtcggcc ggccaaggtc gagccgtttt tacgcctcag nnnnnnnnnn
    46621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    46681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn tgcgcggggt gtcaccccgt cggccggcca
    46741 aggtcgagcc gtttttacgc ctcagtggcc tggaagccct gaccgtgcgg ccggaatcaa
    46801 acttcgtgaa tgtcggcgag cgtaccaaca ttacgggatc acccgctttt tcgaaattga
    46861 ttctggccgg tgactacgac aaggccctga ccgtggcgcg ccagcaggtg gaaggcgggg
    46921 cgcagattat cgatatcaac atggatgagg gattgctgga ctccaaggtg gcgatgcaga
    46981 agttcctgcg tctcctggcc gccgagtcgg acattgcgcg cgtgccgatc atggtcgaca
    47041 gctccaagtg ggaggtcatc gaagaagggc tccgcaacat tcaagggaaa ggcatcgtca
    47101 attccatcag tttgaaagaa ggcgagacca agtttttgga gcaggcgcgc ctcatccggc
    47161 gctatggcgc ggcgattgtc gtcatggcgt tcgacgagcg tggccaagcc gactcggtcg
    47221 cgcggcgcat cgagatctgc gagcgctcct atcgactgct gacagaacag gtcggtgttc
    47281 cgccgcagga cattattttc gatccgaata tcctcacggt cgcgaccgga ttggaagaac
    47341 acaacaatta tgccgtcgat ttcatcgaag cgacgcgctg gatcaaggcg catctcccgc
    47401 tggccaaggt cagcggcggc gtcagcaata tctccttttc attccgcggc aacaacgtgg
    47461 tgcgcgaggc gatgcatgcc gcgtttctct accatgcgat tcaggccggc ctggatatgg
    47521 gcatcgtcaa cgccggtcag ctggccgtgt atgaagaaat tccgaaggac ctgctcgcgc
    47581 tggtggagga cgtgctgttg aatcgccgtc ccgacgcgac tgaacggttg gtgacgtttg
    47641 cggacacggt caagcaaaag ggcaaagcgg cggttaaaga cgatgagtgg cgccagcggc
    47701 cggttgagga gcgtttggcc catgcgctgg tgaagggact gacggactac atcgatcagg
    47761 atgttgagga ggcgcgtcag aaatccgctc ggccgctcga tgtcatcgaa ggggcgctga
    47821 tggccggcat gaatatcgtc ggcgatcttt tcggttcggg gaaaatgttt ttgccgcaag
    47881 tggtgaaaag cgcccgggtc atgaagaaag ctgtcgcgta cctcatgcct ttcatggagg
    47941 cagaaaaaca gcgattgggc acctcccgcg ccaacggcaa ggtgttactc gcgaccgtca
    48001 agggcgacgt gcacgatatc ggcaagaaca ttgtgggagt ggtattgggc tgcaacaact
    48061 acgaggtcat cgaccttggc gtcatggtgt cctgcgaaaa aattctggag accgctcgtg
    48121 aacagcaggt ggacatggtg ggcctgagcg gattgatcac gccatcattg gatgaaatgg
    48181 tgcatgtggc caaggagatg acgcgccagg gattcacggt gccattgctc attggcggtg
    48241 ccacgaccag taaggcccac acagctgtga aaatcgcgcc gtcctacgcc aatacgacgg
    48301 tgcatgtgct ggacgcatcg cgcgccgtcg gggtggtggg aagcctgatc aacaagcagc
    48361 aggaacagga attttctgct tccattcgcg cggattacga tcgcatccgc caggcgcatc
    48421 aggaccgagg gagcaaggca ctccgcaccg tggaggccgc gcgaacccac cggatgccga
    48481 ccgattgggc ttcagccgac attcccacgc cctcgttcac cggactgcgg cagatcgatc
    48541 gtatgccgtt gcgcgagctg gtgcccttca tcgactggac tccgttcttt cacacgtggg
    48601 aattgcgcgg ccggtatccc gagatattgg aagacgccac tgtcggcccg aaggccaagg
    48661 aactgctggc cgatgcccag gcattgctgg aggagatcat ccgcggcgaa ttactcacgg
    48721 cgcgtggagt ctatggattg ttcccggcca atagcgtcgg cgatgatatc gaattgtatc
    48781 ggaatggcga tcgccgtgat gtcctcacca cctttcatac actccggcaa caaacggaga
    48841 aaccggccga tcagttcaac ctggccctgg ccgactatgt tgcccccaag gattctggcc
    48901 gtggcgacta cgtgggggct tttgtggtga cggcaggcat cggtgtggaa gcgctctgtg
    48961 cgaagtatga gaaggaccac gatgactaca actccatcat ggtgaaggcg ctggccgatc
    49021 gattggcgga agcgttcgcc gaatggctgc acaagcaggt tcgccgtgaa tggggatacg
    49081 ggaaagccga gaccctgacc aacgaggata tgattcggga gcggtaccgc ggcattcgtc
    49141 cggcgccagg gtacccggct tgtcccgacc acacggaaaa gcgaatcctg ttcgatctcc
    49201 tgcaggctga atcgcagtcg ggtgtgacgt tgacggagtc ctatgccatg ttaccggcgg
    49261 cagctgtcag cggtctctac tttgcgcacc ctggggccaa gtattttgcc gtggggaaaa
    49321 tcaaccgcga tcaggtggaa gactatgcgg cgcggaagaa gctttctgtg ggcgaggtgg
    49381 agcggtggtt ggcgccgaat ctcaactacg acgcatagca ggataatgga agagttgcag
    49441 attcgttctt gcctcacgca caggttgaac ctactctcag cgtacgcctc ggcccaagac
    49501 agggccggct cactcgccgg tcatggtcag tttttgacgg cttcgagaga tgcgggcaaa
    49561 gtcggggagg gggctacgcc gcttaagatc ttggcaagcg ccgccttgat cgaatggtaa
    49621 cgtgcttccg cccaggtatt gaactcgtct gaattctcaa acaccagttc ccaggctttg
    49681 gcggcatcca gcagcaagag ctgatgcggc tgagtggggc cggggaaata cactaccaat
    49741 acggccgatt ttcccgtgag gctgatatcc gtgaacacgt ggatcatggc ggccgctggc
    49801 agcggcatat cacgtgtggc cgcggcgacg agcggctggt acaaccgctg gagcaagtgc
    49861 gtcgtatcct cgtacgggca cgtcgtgcgc aagagtcgcg ggttgggctt gtccccgaac
    49921 agattatcgg tcaggtaggt ggcggcttcc cacgtcggca tcatgccgga ggaggccaga
    49981 ttctcacaca gataggcgat ccagtttcgt gacgtccgct tcatacggct tccccctggt
    50041 catgagtgat ggcacgatgc cgggaggagg acagccagct cggatcagcg aattgatcga
    50101 aaatccgttt gacgtcagcc atggattcga aaaagatatc gagcaggtcg ggatcaaaat
    50161 gtttgccccg ttccttcagc atcagttcct ttgcgtggtc gaaatcaaac gccggcttgt
    50221 acacccgctg cgtggtgagg gcatcgaagt tatccgcgat tgcgacgatc ctgccttcga
    50281 gtggaatctc ctcccccttg atcccgcgag gatagcccgt gccgtcgtac cgctcgtgat
    50341 gggtccaggc gatgagcgcg gcgaccttca gaaggtctga gtccgacccg gccagaatcc
    50401 tgtagccgat ttctgtatgt tgcgtgatga ctttgaattc ctccggcgtg aacttgccgg
    50461 gcttgagcag gacatggtcc ggggtgccga tcttgccgat atcatgcatg gggctggcgg
    50521 tgcggatgag atcgcatcga tcgggcgata atccgtaccg gcgtgccaac agctcgcagt
    50581 agtggctcat ccgttggata tgctgtgcgg tcgagctgtc gcgatattcc gcggcgatgg
    50641 cgagtcgttg aatagtttct tcgcgggaga gccgcagttc cttttcgctc cgctccagcc
    50701 attccaatgc ctgttgcagc gcaatcgtcc tggtccggac gacctcttca agattttccc
    50761 gatgcatggc attttcgatt tccagcttgc gacggcgtaa cgcatttgcc acgttgatca
    50821 ggacttcgtt cgcctcgaag ggcttaatga tgtatccgaa ggcgcccata tccagggcgg
    50881 cattggccag gaccgggctg tcgagcccgg tgatcatgat gacggccgtg ttgggatatt
    50941 gcgtcaaaat gtggcgaatg agatccatgc ccgattcgcc aggcatgttc acatcgcaca
    51001 acaccatggc gtagtacccg tcctccatcc gttgacgggc ttcgcgagcc tcaccggcca
    51061 gggtcacctg gtagccatgc ggctcgagca aataacctaa caggcggcga atgggctctt
    51121 cgtcgtccac aatcaggata tggcggtttt cgagaatgga ttgttgcgtg gtcacttcac
    51181 tgacgctcgg gatgctcata cggctcactc gcgggttaag gtcaagtgct gctgaatcag
    51241 ggatagaatc agtatcggtt tttaccaact cattctgaag tcatggtagc tggttcctga
    51301 attttgcacc ttttgtgcca atacaacctc cctgccgtgg gctgcagaag tacattgaat
    51361 ggcccaacaa tgagcaggac tgatccagat ccggacagga tcctagtcgg cggtaagggc
    51421 gtggccgtca agtctgacgc cggtcggtcg gctgacgtcg ggaatgtgtc gtttacggac
    51481 agccaatcta tgcagccatt gtggtgaatt atacaggggc acttgctgaa tgccagttca
    51541 aacgcagttt gagaaatcgg tggactcgtt cggctgtcgg gatttgctct ttgaggggcc
    51601 gttcactata atccgctcct ttggattgcc gtgcaggaag gagcgcgact gaatgacgag
    51661 cggggcagga ttggggcgaa ttgatgggcg gcgacgggat caaatccgcc ccgtcaaagt
    51721 gacgcgcaat tttacgaagc atgctgaagg ctccgtcctg atcgaaatgg gcgacaccaa
    51781 ggtgatttgc accgcgtcgg tcgaggagaa agtcccgccc tttctcaaag gaaagggcac
    51841 cgggtgggtg acggccgaat atgccatgtt gccacgggcc acccatgatc ggtcgccgcg
    51901 tgaatcggtc aaggggaaac agggcggccg gacgctggag attcaacgcc tggtcggacg
    51961 ggctctccgc gcggtcatcg ataccggacg gttgggtgaa cgaactatct ggatcgattg
    52021 cgatgtcatc caggccgatg gcggcactcg caccgcttcg atcaccggat cattcatcgc
    52081 cttggcggat gccatcaccg tgctgaaaaa gaaggatctg ctcaaggtca atccgttgac
    52141 cgactatttg gcggccatca gcatcgggaa ggtcggtggt caggtgatgg tggatttggc
    52201 ctacgaagaa gattcccatg ccgaagtcga tttgaatctc gtcatgaccg gggcgggaca
    52261 atatgttgaa gtgcagggaa cggccgaacg cacgcccttc aacaaaaaag atatggatga
    52321 gtttctggat cttggttggg gcgccatccg ggaattagtg gatttgcaga agtcgctgat
    52381 cggcgccttg agctaaccat gcagatcgtg ctggccacga gaaatcagca taagaagcag
    52441 gaacttgtcg cgctactggg cggcttggac atcaccattc ggaccctcga tgattttccc
    52501 gaggctccgg aagtggtgga agacggtgag acctgcgaag cgaatgccat gaagaaggcc
    52561 gtggagatct cgcgtttcac gggattgccg gcggtcgcgg acgatacggg gctggaggtc
    52621 gatgcgctgg gcggtcggcc gggagcgttc gctgcacgat atgccggcga gcatgcgacc
    52681 tacgaagaca attgcaggaa gttattgcag gagctcagtg gcattccgcc tgcgcgacgg
    52741 ggggctcggt ttgtgaccgt ggccgccatc gcgtttcctg gcggcaagac catgtcggcc
    52801 aagggcctgt tggaaggggt cattgccgaa tcggtcgtgg gctccaacgg attcgggtat
    52861 gatccggtct ttattctgcc ggagtataat cagacgttgg gacaattgcc gccggaggtc
    52921 aagaatcgaa tcagccatcg ggcccgcgcc tttgcgcaag cgaggacgtt gctgcaacaa
    52981 gcgatggcgg agcactcagt cggggcgtag cgcagctcgg tagcgcgcct gctttgggag
    53041 caggatgtcg gaggttcaaa tcctctcgcc ccgaccaaat tccttccctc ggtctggatt
    53101 ccttccgttt tttccgattc caatctgcgt caggctccac tgccactcag tgagctcccg
    53161 aggaacttcc acccgcttta ttcagagccg acagactgat gccgctgttg aagcgtcata
    53221 cggatgccgt ttttcggccg caacgtcacc atgacttccg gctcgacgtg gtcctgtgcc
    53281 agctgaggat catagcgttg accgatcagc gccaaaagca gggggccttc tactgtcgcg
    53341 aagtgcgtgc ccacgcaggc acgcggtccg acgccgaagg gcaggtaggc gcagcgggaa
    53401 ggcggacgtt ctccgtccag ccaacgttca ggcaggaact gttccgggtc tgcccaaaaa
    53461 gccggatgcc ggtgcaggtt atataagccg acgaggacga tggcattggc cgggagggta
    53521 aatccgccga gcgtggtctg cgtcatgctt ttgcgttgga tggccggcac cgggggatag
    53581 aggcggagcg attcatcaaa gatcgcacgt gtgtagggca gatgttgcag atcgtcggcg
    53641 gtcggggttc gcccgcggag aaccaggtcc acctccgtgt gaaaccgtgt cctcacctcg
    53701 ggatgggtgg cgagcaaata ccaggtccac gcgagtgcgt tagcggtcgt ttcatgtccc
    53761 gccgcaaaga tcgtcagggc ttcatcacga agttcctgat cggtcagtcc catgccggtt
    53821 tcctcatccc gagcttggag cagcaggttc aggaggtcgt catagtgcgc gccgctctgt
    53881 cgccgggccg cgaccaattc gtagatcagc gtatccatga atttcagggc tcgactgaac
    53941 tcacggttgc gagcggttgg gacccagacc gggagatgca gcgggttatg aaatgagtcg
    54001 aacgcatatt tcaaactcac gcgaagagaa tgactgatct gatccatatg ctgagcgacg
    54061 ctggtatgaa acatcgtttg ggaaatgact tcgagcgtca actgcatcat ttcagcggcg
    54121 atgtctaccg gctgctcgcc atgagtcgcc cacccggcga gccgttgttc tcccacctgc
    54181 accattcgat ccgccatcgc ggccatacga gagcgatgaa acaccggttg aatgatgcga
    54241 cggtgccgct tccacacctc cccggaactc gtcaccaatc cattacctag cactagcgcg
    54301 agtccggtgg gacgttgctg ttcgtacact tttccaaacc gctcggcttg tgagagcagc
    54361 acctcttccg ccaacgcggg atggctgaag agatgaatgg tcttgggacc aagtcgaaac
    54421 cgcaccgcat caccctgctg gcgccaccat cccgacattg tacgcaacgg ttgatgcttg
    54481 aatgagcgga ggtgtccaag ccagggcagt ccaccgggca cgtcagtcag cgtaaaggaa
    54541 gggtttgagt cgatatcctg catgagtcaa gaaagagtcg attgtggtat gcgaggaggg
    54601 gttatcccgc acctatgtgt ccttctcgac ggggaggggt cggttcgaca atgcactctc
    54661 ctcccatcaa agcttggcat agtacaaact tcgtatggag aatggtaggg ccgatgggac
    54721 ctggacgacg gagccccggt cttcgttcaa cgccgcttca tgagcttgca tgtggcaacg
    54781 aatcgtaact caggaatccc tggttgatgt ctgatatggt gcgcccgctt cgacgaaaca
    54841 ctccgacacc ttcacggtcg ccaggaagat tcgtgttccc ttcgatggtg accaggcgat
    54901 catctcgaaa gtcttccaca agacccatat gtccatgccc accgccggtg ttgatcacaa
    54961 agaccagtcc tggtttcaac agggaaagat cgtccaggat ttgaccggcc accaaacgag
    55021 tgacacctgc ctgtccggct ttcttccaat ggtccagcac gccggctgtg cgaatagcgg
    55081 gattggtggt tcccagccga gttgccgcct gcttgaatga ccaatagacg aatgcggcac
    55141 accaggcgta actccccgtg gaaggatcga ttcccgccgc ctttagatac tcatccactt
    55201 tgggcccgcg gttggaaccg gacggatcct ccatcacgcc gacctgcgat gcggcaatgc
    55261 tgagagtggc tttcatcaac gcggagatcg gcgtggtggc gatcgaaggc acccgatgtg
    55321 cgccgaagag tgcagcccag gtgagtggcc cgacgactcc atcgatcttg agcgattgcc
    55381 cttgtccatc gaccgagcga gcttgcaaga gccgcacggc ttcctgtgtc gctcgatcga
    55441 agacgccgct cacggagatt ggcccgcatc cgacctggtt caatcgctgt tggacggcgc
    55501 gaatcgtcga gggcgccagg atacctgatt tgagggcgta tcctgggtaa tcgagaacgg
    55561 cgtctttggc tcgggctggt cgagtagggg aagcggcacg ggtgcgtcgc ggcatggtca
    55621 gctcctggat gaaggtcaaa cgaagggctt gattattccc atcagtgaaa gcatggcgat
    55681 catttcttga gggcaggcat tatacggcag tcaccgcaat ttgttgcgag tttgattggt
    55741 ccttggtccc acaatcgaat ggcaacaggc ggaacgctgc taaggagtgt atcgtgactg
    55801 aaaggcgggc ggaaccgggt tctgcgggta ggagatcggc tgcctcggaa tgaggcgtga
    55861 gcaacctggt ttgtaacgac tctcagcggt cgcgcaaata ctgccgcact cgttccacaa
    55921 tggcacgatc gtggtcgatc attttcaagt cgtgcgtttc gtcggggaga aaccagccca
    55981 tggcttgccc ttctcctagt tcaagcggtt ggccctggta tcgttcaaca aacacgtatt
    56041 tcgtgttctc gtcttcgcct tccctgaata attgtgtcat gagaaagtgc gggtcttgta
    56101 cgtgatatga caattcctct atcacctcgc gcttcagggc gtcggatgga ctttctcctg
    56161 gctcgatccc acctccaaag aaggcccagt aattgggtaa tcgataggcg tcaggggttc
    56221 gatgctggag gaggagttgt cccgaggacg tatagaggat gaagatcgcg acatttctca
    56281 cagccattct gcaccatagc ctatccgccc aggccaggtg aagaagatct tttgttctga
    56341 ccgatcatcg gagtgagagc aagtcttgac ccctttctaa ttgcgcctcc actagcccca
    56401 tcactgctac aaaaatctga tcagctcctg tgcatgtgac cctgatctag gccatttgct
    56461 aggtcttctc ggggaggaat agcggtacaa ggagcgggga catcatcatc ctccgggagg
    56521 caagctcatg agcaccacca cggcagtcaa acaaaaagga cagacctgcg cccattatgg
    56581 gtgtggatgt cgggtgacag atgaagacta ttgcagccct gaatgtgaat ccgtcgccag
    56641 cggacagacc ggttccgcca tctgcccctg cagtcatccc aactgcaaaa ccccccatta
    56701 aggcttgacg acgtctgggc gctgcgggac tcacgttctg cacctgtatc gcgatgtctg
    56761 tcgatcattc gcggtccgct gacttggaag tgagaagact gattcgtgtt ttcggcatcg
    56821 agaagtcgct cactgtccgc caaattagcg acattcctag tgtgttctag cgaggggcgt
    56881 gggtactgtg tgcacagcgt caccgtttac gagtgctcac atggacttca catatgctca
    56941 cacctcagcg tcctctcaaa ctactgatta tcgacgacag ccccgacttt cagctgctca
    57001 tcaaaaccta cctcgaggat tttggcatcg tctgcctctt cgcgacggat gtcgtgcagg
    57061 caacctccac agcggtgcga gaacagccga atctcatcct gctcgacatt ggcttgccgg
    57121 gaggaggagg cttgctcctc ctcgagaggc tcagagccaa ccttcgcacc gcgaaggttc
    57181 ccgtgattgt gatcaccgcg cagacgaccg atggattgga atcaaaggcg cgatccctag
    57241 gcgctgaaga atttctccac aagcctgttg agaaagacgt attgattgat acactccggc
    57301 gggtgctcag caggccacct acacagcagg catgagaggc gcccagccat cggctgattc
    57361 gttttcaaag ttcccttgtt gggatcaatg ttctctctta cgattcattc gatcgatatc
    57421 gcatcgtgcg gtgcgtcacg ctggaacctc agacctgcgt ccctaatagt gtcccttgtc
    57481 gtcacggcgg tggatgatcc agaaatggct gaggaccaga gacaggatgg aaatgagaca
    57541 tcagtggtgg tgtgaggaga aatctgcaaa gagtcacagg agcgattcat gattcgcctg
    57601 gcgaggaagc ccgacggtat gttctctgac ctgttagaca gtgcgatcac acagatcgtc
    57661 aatgactatc tgacatcggc gaatgcacgg gatcaagagg attggctctg cgcatcgatg
    57721 cctcgcgcgg cccggttttt tactgctccg caagcgagag aacagttgct cgccatgcag
    57781 aagatttacc atgatgaacg attgtatgag gtgaccaaat atcattggtt actcttgtac
    57841 gagtgtctgg aaacctttgc gcagggattc aatgaacagc cggtgggttg gttagctcaa
    57901 aaatacggca ttgaaaagat cgacttccat cgcctggttg acttgttttt ctgggacacc
    57961 tcgtttctga tggatcatct ggccaaaatg agccgtcagg aaacacggac gatgttgatc
    58021 tggccggaat cggtcggact tgcggccggg ttcaagactc atccggacga actcgcgttc
    58081 atcctctgcg acgaaggagt tacagaagag ttcgcagccc aaaaagacgt tcctgcatgg
    58141 tctatcgggt caaagtccta ccccttgccg cacacctagg gaacgcgtat tcatcccagg
    58201 ttctgtatcc catcgtaacc aacgaggcca aatgtcttgg tattggtcaa tgggtatgtg
    58261 gaaggaggga aagagggaag gagattgagg actcacagac actcactaca tcattttttt
    58321 gaatatcgtc agaagccgtt ggcagtaggt aggatcggag gagaactcgg ctccggtgag
    58381 cggcatattt aagaactcgt tatatcccgg cagcgacctg acctcgggcg aattcagatc
    58441 gcgaaacccc atggaccaat caggaaattg tcgcgcgggt atggtttgct gcaagagtgt
    58501 gagcactccg ctatgtcgct catcctgaaa gatttttgca tagagcttca acaccgcttc
    58561 ttcctctccc tcaagggcct gcataaagtt tccattcttg tagagcaaga ttccggtaat
    58621 acctaatcga ctgttgttcg catggcaaga ggcgagcaaa tcagtgagct gtgatggaga
    58681 gaatggtctt gtcgcagaac tggcatacac aagacaaaac attatggcct ccctaggacg
    58741 gtcatctttg ctatcgtccg tcgtaaaaaa actgcgccat atgacgaata atgtgtgtga
    58801 tatcagggat actctgctgc cgttgttgcg ctcgatcaag tcaatttaac tttccttctc
    58861 tcacgttcag gcgtctccgg gctgacgagg gtcccaacgg aatagtcatc ttcagatcaa
    58921 cccgcacaaa ctaggaacat tgctagtcca actcacgtct ctcgatcctt caaaactttg
    58981 tggaacgctc tcagggagag tcacatggca ggtagtgcgg gtgtagcata tgtcacttgt
    59041 gcccagtggt taacctttgt gaagtaagac acaagcatga tgaggcctcc acggcgccag
    59101 tcaaaagcgg ctcttgtctt cttgttcgat gtagacgaga cgctgcttga tgatcaacgc
    59161 gtgttgtccg atcttcggcg tcatttacgg agggaggtcg gacgtgaagg agatcgacga
    59221 tattggaaca ttttacaacg cttgcaccga gcattgggct atgcggacta tctgggtgcc
    59281 ctgcaaaaat atcgtcagtc gtatccccat gaccctcatg tccttaccct atcctccttt
    59341 ctcataaact acccctttgc gaaacgtgtt tttccgcagg ccatgcgtgt cattacacgc
    59401 tgccggcgtg tgggctctgt ggtcattctt tccgatgggg atgtcgtgtt ccagccgcat
    59461 aagattcaac aatccggtct cgccgcagct gtggacgatc atgtcctcgt gtatgtgcac
    59521 aaggaagagc aaattcgcaa cattgaggtg tgctatccgg cggatcacta tgttgtcgtc
    59581 gatgataatg ttcgtatcct caacgtcatc aaaaagatct ggagggaacg ggtgaccacc
    59641 gtgtgggtga ggccaagttc aagtgggaca ggtcggaatg gtattcacgc gcatgcacac
    59701 cccgacctca ccattcactc tattggagaa ctaaacaaag agcgtttgcg cgcgatcaag
    59761 ttgctacaga aagagcagag tcactcttga agagtcgacc tgcacatctg agcacctcga
    59821 cacacttggg gccccaaaat cgacgaatta attcttgccg ttggccttcc cgctttcgtc
    59881 caggtttctc aaaacctgct tgagccgttg tttcaccagg gtttcgagca gtgacttcgc
    59941 ttcaggatct gttttaagta cctgttccat caccagttgg cctgccgtgg ctgctgaacg
    60001 aagtaaaccc tggtcgatgg cattgacgat catctcatcc atggagcctg gcctatgttt
    60061 gtcgcgccgt ttatgtttac tcatgacctc tcctgcgtcg ctcatgataa aggtatgcgg
    60121 ttcatgctaa aaaagtttcc actcacacgt agaaggcggg caacgtgccg gttctccttc
    60181 cagacaaggc agccttgtga ctcctttccc agctgagatt ctggatgtca gagcttggca
    60241 gcggcacaat gtcggtcgaa gtgagtatct tgctgctcga tggcggaatg aatgccggct
    60301 tggaccgtga cgaagccaaa tgatatctca gcgcttctta gctcatgagg catcgaggtc
    60361 catagtcgca aggtacaaag acctgggaat actgggagca tccctggttg gcagttgtcc
    60421 tgtgagatcc ttgggccggt gatcatgcat ccaagttgca gctccccagt gaagcctgtg
    60481 ctgatcttgc cgtatcgttg aagaatagag atgtgactcc ctcgcagtgc gagtgactat
    60541 acgtcacgat cttacctcat cgcttatgat tgggctctca cctaagtagt aggctcatca
    60601 ttattggctc tggcatctgc cattgattgc ctgaagtatg tcatgcagca gggattcatg
    60661 atataagtgt ttatgcgttg tcataatcgg agtatagtac tgctattgcc gcggcgggat
    60721 tgctgttgtg cattcttgac gtatcgttca agaccatgaa aaggagcggt agaatgctga
    60781 attgttctgt gcatcagtgt cgtgtcagga tcgtagctat acttgccgca tgcctagggt
    60841 ggggtggact gataggagtc agttactctg ctttaatcac gtttcagttt gaaggaagtg
    60901 tcatcgctgt ttccccgttt ttgagtccac cgttcagtac gtccaacacg ttccaaggtt
    60961 catatacctt tgattcgctc actccagacg gaaccccttc aacgcaagcc ggtaattatc
    61021 tgcttacgaa cgcctcggta accttgggag gcaatacgta ttctgccaat atggcgccca
    61081 ctgtcactcc tccgctgatc acggtgatta gcaactcgtt tggaagaccc actgactttg
    61141 cattatccga tgatagctat cgagtctcat ttcgaccatc tggtcctgcg gtcaatgaac
    61201 tgctcccgtc ttcattttct atgtcaattt ctggccttag acagtttccc aatgattccc
    61261 tcccgttaac tccgccaagt ctatcaggca gcgacacacg gataagcctg ggctttgttc
    61321 agccactagg taaagttgga ggagttacgg gccaactcac ctcgttgaca gttgctccag
    61381 tgcccgtccc cgccgctgcg tggctgtttg gaagtggttt ggctgcagtg accgcgctgg
    61441 ccaggcgcaa gcgaaaagca aggcttgaat ccaccggctg ttaattcgtc cgttaaagga
    61501 gctgccccgg gacatggatt tcatctgcat gtcccgggct acccactcca ttaaatcctt
    61561 tattctttgc ctgccactag tacaactcct gccatccttg cttcaaaaat tcctctgccg
    61621 aatccccaca atgaacggga tcgtgtattg accgatgagg agtgagggcg attgtatagt
    61681 gaggccaaga cccgtctgag gagggctctg ctcacagcct atcaatttgg acaacgattt
    61741 agcgaaattg tcggactcac ttgagatcgt gtcgatgtga agaggggatt tatcaccctt
    61801 cgttccctgg acaccaagac caaaactgct cgtcaggttc ccatgacacc cgatgtcaaa
    61861 atgaccttgc agcgacttgc tcggagacgc agtcttgcca cgagacacgt attaccgtat
    61921 aaaggccgac gcgataaaac gcgtcagccg ttctttcagg accgccattg cgaaggctga
    61981 tattgccgat ttccggtttc atgatctgcg ccactgcgcc tccactaatc tcagaagagc
    62041 aggggtggat acggccactg ccatgaaaat tgtggccaca agtccgacaa gatgtggaaa
    62101 cgatacaata cgatcgaggc gcgagacttg actcgggctg cccaaaaggt tcacagatac
    62161 ctccaagaga acacgccggg aacactaggc gaaagctctc ttggatactc atctcataaa
    62221 tgattgaaaa ataagtgtgc gcccgtagct cagtcggata gagcatcagc cttctaagct
    62281 gagggtcgtt ggttcgattc caaccgggcg caccataaaa tcaacaggtt gtgaaacagc
    62341 ccctccaagg ttactgagac cactcccggt tttactcccg gttcgcactt cggcctgact
    62401 ttcttgaggc gaagcaaaca agctgccctt ggccacggtc tcctgcatga agccgggcgt
    62461 caggtggctg tatctcgccg tcgttttgat atcgcgatgt cctaaaagct gctgcacgcc
    62521 atagagactc gcacccgata ataccccgcc gggtggcggc cgtatgcctc agggaatgcc
    62581 agctcgcgcc gacgattccg gctcgccgta gcgctgggtc aaagtaccat ctgacaaatg
    62641 agcgggcgtc caagggttta agagggtctt tcccgggaaa tacgaaaggg gacttcgtga
    62701 atgaatccca cctgg
//
LOCUS       DAOQPD010000012        60748 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_173_length_60748_cov_24.898885, whole genome shotgun sequence.
ACCESSION   DAOQPD010000012 DAOQPD010000000
VERSION     DAOQPD010000012.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 60748)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 60748)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60748
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_173_length_60748_cov_24.898885"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            454..1614
                     /locus_tag="PK063_04685"
     CDS             454..1614
                     /locus_tag="PK063_04685"
                     /inference="COORDINATES: protein motif:HMM:TIGR03696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat-associated core domain-containing
                     protein"
                     /protein_id="HMZ96371.1"
                     /translation="MTYTYDKGGNRITQLRQNAAGSNLPTAVAAANIAYDAANELTRW
                     NSATTNLTYNSNGNLATETQGGLTTTYTWDARNRLSGISRTGLTASFAYDALGRRKSK
                     TINGATTGFWYDGNDVYAEIMGATPSATYIRGLSIDEPYIRKGANDEFYETDALGTSI
                     ALTNAAGASQTTYTYQPYGVSTQLDTPSSNAFQYTGRDNDETGLIYYRARYYHPNMQR
                     FVTEDPLRFRGGENNFYVYTNNSPTQASDPLGLFMIDSATCRNKDTRGFIRSMAAVAY
                     DTAMNKPNCLNCSQRQAFKARWEDLVISCWPSNYTPNGRPACGFQNDSLGTNVIWLTP
                     QGLNAQGCWSVPGTIFHETLHTLTSMLGPEYAGEQIVRELEANCFTRPPTMK"
     gene            1634..2146
                     /locus_tag="PK063_04690"
     CDS             1634..2146
                     /locus_tag="PK063_04690"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96372.1"
                     /translation="MTGMLMAVRNLAFLLLVVLPLSYVDNSDGKIVEEDLEAMVHESK
                     LIVLGKVASAEFTGQILTDEFKIGKWSLFKAVIKPDLVIKGRLQQDELDLYYIGGMST
                     EARFNVNDTSIFFVDEDDQGRLATVRGYAGKVDITQQVAMPVAIRNEENPQPLDAFIR
                     KIRAIVERAR"
     gene            complement(2535..2951)
                     /locus_tag="PK063_04695"
     CDS             complement(2535..2951)
                     /locus_tag="PK063_04695"
                     /inference="COORDINATES: protein motif:HMM:NF013970.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family
                     toxin"
                     /protein_id="HMZ96373.1"
                     /translation="MPQPAVLLDTDILSELLKQHPLVVQRVRSYLTEHQRLAFSIITR
                     YELLRGLKAKQARTQEAAFTLLCQASLILPITDQVVERAATLYGDLHRQGALLPDADL
                     LIAATALDAQRPLITNNLAHFQRIPGLIVESWKRSV"
     gene            complement(2951..3187)
                     /locus_tag="PK063_04700"
     CDS             complement(2951..3187)
                     /locus_tag="PK063_04700"
                     /inference="COORDINATES: protein motif:HMM:NF014059.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin family protein"
                     /protein_id="HMZ96374.1"
                     /translation="MRQTIKARYHDGVLQPLEPLSLADDAEVQVTVDTDLALGTDEIL
                     RRAAQVYQGLSADEITQVESIALDRQHFFREPAA"
     gene            3614..4318
                     /locus_tag="PK063_04705"
     CDS             3614..4318
                     /locus_tag="PK063_04705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MEDS domain-containing protein"
                     /protein_id="HMZ96375.1"
                     /translation="MHSALTTPTEITASTPRHQCLIYKGSPATHFSGLSAVIRQKLTE
                     NYRCLYFNTSAMIAAMRPYLLAAGIDIPQEVERGRLVLSSNPTHLTDGHFSIDRMLGM
                     LEEGLNQALQDGHAGFWCTGDMTLEFGPERDFSKLLDYEWRLETFLQSHPALSGICQY
                     HADTLPNEVLRQGLLAHPSLYINETLSRLNPHYVDRESFTAATYHDPALDKTIRALCM
                     VPDALILNALPPGYLH"
     gene            complement(4457..5314)
                     /locus_tag="PK063_04710"
     CDS             complement(4457..5314)
                     /locus_tag="PK063_04710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HMZ96376.1"
                     /translation="MPDTPFSESRSGPPSHGHLSLRSLLISALAWPFKTFIRRLIGEV
                     FYQQARVTLLHEHGGVGLDWRWGNSLRRVHPIRRDFGWQSGRPIDRYYTEDHFLPAYQ
                     ADIRGRVLEIGDDRYTRQFGGERVTLSEILNVNPGMGGTTIQADLTDAKQIPSNTYDC
                     AILTFTLQFIFDVPAALRTLGRILRPGGVLLVIVPGISHIARYDMDNWGEFWRFTSLS
                     ARRLFEQVFRPEDITITTYGNVLSSLASLHGLHSTELTTAELDHWDRDYELVIGIRAV
                     KRPAANTSL"
     gene            complement(5912..6688)
                     /locus_tag="PK063_04715"
     CDS             complement(5912..6688)
                     /locus_tag="PK063_04715"
                     /EC_number="4.2.2.n1"
                     /inference="COORDINATES: protein motif:HMM:NF013618.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HMZ96377.1"
                     /translation="MAQEQSARDQESFSRTSSVDDCLDGKTRTSVSWALPLAIAGVLV
                     VGDSASAENDIYGYVGANGVFEMTNVPTDGRFRPAELQRSRLSHRASVEEVEDAVERY
                     AWQFHLHPALLLAVIKAESDFNPTVISRAGAVGLMQLIPETAIRHGVHNLYDTGDNIR
                     GGARHLRYLLDRFNGNIRLAVAAYNAGERRVERYHAIPPYPETRDYVRKVMIYYKSFR
                     GDYQATPGKAVLLAMHHKRLQLEPLSVPVDFRHGRPAAKK"
     gene            7200..8129
                     /locus_tag="PK063_04720"
     CDS             7200..8129
                     /locus_tag="PK063_04720"
                     /inference="COORDINATES: protein motif:HMM:TIGR00254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing response regulator"
                     /protein_id="HMZ96378.1"
                     /translation="MIKLLLVEDNSVDAQLTQDLLAEWSLDRFEITHASVLADGLTRL
                     SRERFDVVLLDLSLPDTHGLATVTQVLATSPDVPVVVLSGHDDHPLALQALQHGAQDY
                     LVKGEGGTEFLARSILYAIERKKAQERLTYFAQHDPLTGLINRALFRDRLIHAMARSK
                     RKDQPLAVMLLDLDRFKAVNDTLGHDIGDQLLKEVATRLMECVREVDTVARLGGDEFT
                     AILEGISGEDDVLVVAKRIVDSIGSPFQIGPHNISIGVSIGITLYPSDDEDLDELLRH
                     ADKAMYAAKQQGGGRYHFHSPAGHSPDVPAPLP"
     gene            complement(8191..9024)
                     /locus_tag="PK063_04725"
     CDS             complement(8191..9024)
                     /locus_tag="PK063_04725"
                     /inference="COORDINATES: protein motif:HMM:NF024627.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HMZ96379.1"
                     /translation="MDTSHEAGSSGAGKDPLIEPPPNPKGGKTLIVDARDSDAYLCPS
                     AALKDAGEDDQVFVRPGVYEDKVFVADKPVLLVGAGRDQVQIYSRRGGPLYLQRVPNG
                     MISGITFRYVGSDQHSAMNVLDSVCTITRCRAMEGILSGVVIYGPEARPTFIDNEVCS
                     NRESGIFVFAGAQPRVAQNLCYGNHHFGLAVRDPGSHPECVRNVCHSNMLSGMLLFHH
                     AEALLLDNICRDNQHWGLVMTPDSHPTPSQEELVAGNVFLPNPRGSVVVTEQPLADIG
                     R"
     gene            9333..9854
                     /gene="ybgF"
                     /locus_tag="PK063_04730"
     CDS             9333..9854
                     /gene="ybgF"
                     /locus_tag="PK063_04730"
                     /inference="COORDINATES: protein motif:HMM:TIGR02795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system protein YbgF"
                     /protein_id="HMZ96380.1"
                     /translation="MTMVQLSREKVRGIAAALALFSILASASDLFAASPQQPDASRRL
                     YDRVMDEFRHKDYPAALAGFRFFLELHGHSSLSANAQYWMGECQYRMGKHDEALGSFF
                     KLISDYPMSQKLAASTLKIGQIYTKQGDLEKAQMMYERVTGEYPDSPEAEVARKAIEA
                     AAAKGDPIAAGPN"
     gene            complement(9919..10443)
                     /locus_tag="PK063_04735"
     CDS             complement(9919..10443)
                     /locus_tag="PK063_04735"
                     /inference="COORDINATES: protein motif:HMM:NF022337.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="HMZ96381.1"
                     /translation="MNMDVLYPLLAIGALVLLGSLAWETFGRRRAPAASSGSLPSGLT
                     FAPKPLLTDQEVQLYNLLRLAVEDRYLLFTQIPLWSVLDLRVPSGMPPAETLRELALT
                     RATFVLVHPGSRLVEKVVQVEPSASQAEGQGTANSLFDGALRAAGVQLVRLSPFHTYT
                     VPGLVTVLDLADPD"
     gene            complement(10453..11637)
                     /locus_tag="PK063_04740"
     CDS             complement(10453..11637)
                     /locus_tag="PK063_04740"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: protein motif:HMM:NF007148.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HMZ96382.1"
                     /translation="MKVVGLMSGTSADGIDAALVNIVRRGGRPVITPIAFSTVPYPRA
                     LQQRVVDLSLHGQVAEICHMNAYLGELFAEAALKVIRAAKHQPADIHAIGSHGQTIHH
                     LPKGRRESGVGLIRSTLQIGEPAVIAERTGITTVANFRPRDMAAGGEGAPLVPYAHAV
                     AFSHARRTRLVVNIGGISNVTYLPAGGVMADVRAFDTGPGNMVLDAIMQETTKGNRTY
                     DAGGRLARKGTIHQPLLTELMAHPFLTRRPPKSTGREEFGAPLVRRLLAKQKKARLSI
                     EDLLATCAAWTAEAIGSSRRWVPGKIDDVIVGGGGVSNRAIMASLRTVFAPAPVLTFD
                     ECGWSSKAFEATAFALLAHDVLHGHCTNVPQVTGARHPVLLGSVVPGKADIRRRNRYL
                     PG"
     gene            11799..12719
                     /locus_tag="PK063_04745"
     CDS             11799..12719
                     /locus_tag="PK063_04745"
                     /inference="COORDINATES: protein motif:HMM:NF013465.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HMZ96383.1"
                     /translation="MFRTILLTLFIFLTMLGNLSAAVPTASAAEPLNVVVTLPVLKDW
                     VQQIGGSHVHVVSLMTGYESEHTYSPKPSDLVAVRKAALLFEVGAGLEVWVSSLVKNA
                     GNASLQVVTTSKDIELIPDHPESTADAHTHHHAGGNPHVWLDPSAAATMVQHISKAMV
                     EADPAHAAEYRNNTADYLQALLRVQAESLERLKKVPSRAVIVHHPAWPYFARRYDLQI
                     AGTILTQPGGEPSARHLHTLIDAIKRGHIRVIISEVQLNQKVPQLLARETGAHIAVLT
                     TLPGGLPGTETYLDMLRYNVLQLAHALEQT"
     gene            12777..13559
                     /locus_tag="PK063_04750"
     CDS             12777..13559
                     /locus_tag="PK063_04750"
                     /inference="COORDINATES: protein motif:HMM:NF012234.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HMZ96384.1"
                     /translation="MTHPIIRFDHATFGFPGTVALEDISLSIPESEFVGVIGPNGSGK
                     TTLCRAVLGLMAPIRGTLRVLDCACEELRCHHRALIGYLPQKGMLDRNFPVTVLEAVM
                     MGRYGALGLFRRPSGKDRDIARQALTQVGMDHHRDSALGALSGGQQQRVFIARALAQQ
                     PRILLLDEPTTGLDLTAQHSVVELIQQLHQELKLTILMITHDINMIRSRVDRLVLLKT
                     KLFAAGPPQDVLKPEILSQVYGKELVITDKDFIIVEDYHHHH"
     gene            13646..14467
                     /locus_tag="PK063_04755"
     CDS             13646..14467
                     /locus_tag="PK063_04755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HMZ96385.1"
                     /translation="MLELLAYDFMQRSLLAAALVGSVCSVIGVFVVLRGLAFAGAGTA
                     HAAFAGVTLAYLLGLPPLSLAIVFGLATVWITGWVEEKGRMKLDVSIGILYTATMALA
                     ILFLGLMKTYNPEVYGYLFGSVLSVTTEELLTIGGLSIAVLGTILLLSKELYFIAFDQ
                     EMAAASGVPARQIFYLLLTLVALTVVIALKTVGAILVFAMILIPASTAYQLTHSLTQM
                     TLYSMLIGIFCAVTGVLLSYAFDLPSGPSIVLLATSLFFLAVCCSPKRLHRIQAE"
     gene            complement(14567..15007)
                     /locus_tag="PK063_04760"
     CDS             complement(14567..15007)
                     /locus_tag="PK063_04760"
                     /inference="COORDINATES: protein motif:HMM:NF012792.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HMZ96386.1"
                     /translation="MPPALKTGQRPIAFSDRNDFDATQLIHLYRQAPWAKHRALEQAQ
                     AMLAKTDLVISAWDGPRLVGFGRVLTDYIFRASIWDVIVDRDYQGQQIGTEIVRRILD
                     HPTLQQVELFWLCTRMPGFYERLGFSAKEQTGMVWSRKQPSTQS"
     gene            15071..15250
                     /locus_tag="PK063_04765"
     CDS             15071..15250
                     /locus_tag="PK063_04765"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96387.1"
                     /translation="MGTQVRSCPKCFQLMWLKQDHYDVIDEETVRTKCPHCDSTVRFQ
                     LVTAGANAAGPKMGH"
     gene            complement(15339..15761)
                     /locus_tag="PK063_04770"
     CDS             complement(15339..15761)
                     /locus_tag="PK063_04770"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96388.1"
                     /translation="METSAVLDRIGELIAQLKGYAAKLPTVVHLASVPTGVKPKPEAV
                     EAFEQALLRFREQSGRSPFKGLQEYLLESLEAFEVGNVLGSVQPLMAVLDQVERMQRD
                     KEIKVSPAEDKRMGEYRAALIKILPGNQPELEGAGRGM"
     gene            complement(15775..16806)
                     /locus_tag="PK063_04775"
     CDS             complement(15775..16806)
                     /locus_tag="PK063_04775"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HMZ96389.1"
                     /translation="MNRVSTTPVEIVVTGGESSKRIDVFLANRDPTFSRSALQRLIGE
                     GRIQINGQPVRPSQKIRPGDRIRLEVPRPEPLDLQPEAIPLEILHEDSDLLVLNKQAG
                     LVVHPAPGNWSGTMVNALLHHFATAGVTPSHIGGKERPGLVHRLDKETSGVMVIAKTD
                     QAHRALAAQFKLHTITRVYEALIWGVPKKGHGLIELAIGRDTKERKKFSARTTNPKAS
                     ATDYQVEERYGKIAAQVRLSPRTGRTHQLRVHLTSIDHPILGDKTYGGAKVMTVAGIP
                     IPRVMLHARTLGFTHPTGGEYHEFDVPFPPDMEQVQHLLRDALTQGRPAGSDVQSTKQ
                     EADRSSRRG"
     gene            17188..17673
                     /locus_tag="PK063_04780"
     CDS             17188..17673
                     /locus_tag="PK063_04780"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ96390.1"
                     /translation="MSSNFIHRILRSLRSSVDPTPSVEPLVVDNITDLPLTEVLRERR
                     LDARFAVRTPCLYELDRKQRRETPVISGKAHSLNVSSGGVLLLLDQQPQTGQVLSLHN
                     PTLHSQPGTSLFEVRWTTSLPLGAQQGCYLVGCHLAFGRFPFFLVQRQYLHRDISSLS
                     I"
     gene            complement(17722..18669)
                     /locus_tag="PK063_04785"
     CDS             complement(17722..18669)
                     /locus_tag="PK063_04785"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HMZ96391.1"
                     /translation="MQTEFLISPGEQPKRLDIFLVNREPKLSRAAVQRMISAGRVRVN
                     NQTAKPSQKIKPGDVVNLDKPKPTPLLINGQPSALEILFEDSACLVINKPAGVAAHPG
                     PGHWDDTLLNALLDHALRAGVVGMSGLVHRLDRDTSGVMVVAKTKTAHGRLAVQFEQH
                     SITRQYEALVQGVPQHSHGRIELALGTDRNNVKRTSPHTLHPKASLTEYYVEEVFGAA
                     AAHMVLTPRTGRTHQIRAHLHAIGHPILGDPAYGAEPVRALEGYGVPRVMLHAYKLGF
                     HHPLTGRYCEFTVKPPADFRGLSDELRFKTVREGRGRTQ"
     gene            complement(18825..19466)
                     /locus_tag="PK063_04790"
     CDS             complement(18825..19466)
                     /locus_tag="PK063_04790"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96392.1"
                     /translation="MDNAKPAKPVFTPVEIDLVEPAVREAFGKARPGEWIAFLLLEPN
                     AGATGVTSGGLFLESHRLHVVVANHRTMVGNNSDELVRVRANPFYSIQGSGGVLAFEP
                     SRFRLSTKANWSGGHRASASELVLDHSAFLSYVTHAAPREMPTSAPSPIRQQSSAEAL
                     TSPADASVQGGPHDQPMLPQIQGEIERLKQELAEKDLEIDRLKAQLLKSGARP"
     gene            complement(19780..20202)
                     /locus_tag="PK063_04795"
     CDS             complement(19780..20202)
                     /locus_tag="PK063_04795"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: protein motif:HMM:NF009980.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HMZ96393.1"
                     /translation="MAGKILLEVVTPEKLLLSQEVDEVIAPGSEGEFGVLPGHCHLLS
                     SLRIGELRYKSQEVWHYMSILWGYAEVTPVKVTVMAEIAEKAEDIDVGRAQQAVEKAE
                     QRLQAGGLPSEVREAEISLEKARLRKKIADRARKTGHA"
     gene            complement(20316..21758)
                     /gene="atpD"
                     /locus_tag="PK063_04800"
     CDS             complement(20316..21758)
                     /gene="atpD"
                     /locus_tag="PK063_04800"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000275 - mitochondrial
                     proton-transporting ATP synthase complex, catalytic sector
                     F(1) [Evidence IEA];
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HMZ96394.1"
                     /translation="MSTGKVIQVIGPVVDVEFPPGQLPNIYNALKVTQEENKAAGKPA
                     VRITLEVASHLGENRVRGIAMSTTDGLTRGMDVTDTGAPIAVPVGRETLGRLINVLGE
                     PVDEKGPIKTNKTYPIHRPAPRLEDQDTKTEVLETGIKVVDLLEPYSKGGKVGLFGGA
                     GVGKTVIIMELINNIALHHGGFSVFAGVGERTREGNDLWHEMQESKVIDPDDHTKSKA
                     ALVYGQMNEPPGARLRVALTGLAVAEFFRDEENQDVLLFVDNIFRFTQAGSEVSALLG
                     RMPSAVGYQPNLSTEMGALQERITSTKKGSITSVQAIYVPADDLTDPAPATAFAHLDA
                     TTVLSRQLAELGIYPAVDPLDSTSRILDPQVIGEEHYKVARGVQSVLQRYKDLQDIIA
                     ILGMDELSEDDKMVVARARKIQRFLSQPFHVAEAFTGAPGKYVKLKDTVRSFKEILEG
                     KYDHLPEQAFYMVGPIEEAVAKAEKMGVKV"
     gene            complement(21826..22710)
                     /gene="atpG"
                     /locus_tag="PK063_04805"
     CDS             complement(21826..22710)
                     /gene="atpG"
                     /locus_tag="PK063_04805"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000275 - mitochondrial
                     proton-transporting ATP synthase complex, catalytic sector
                     F(1) [Evidence IEA];
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HMZ96395.1"
                     /translation="MPSLQSLRRKIAAFKNTQKITKAMKMVAAAKLKRSQDRILAARP
                     YAHKMRGVLSNLSQRVNRTSHPLLQKREGKKIEILVVTSDRGLCGGFNGNIVRKSAEF
                     VRQCESQGLSVNLSLIGRKGRDYFRRRSLPIRQEWTGIFDKLSFEHAIDIGGDLTENF
                     VKGTFDELYVVYNEFKSAIQQRVIVEKLFPIDAATEFGASQATEGSSLGGSYLYEPDE
                     GELLSALVPKHFQIQTYRILLESAAAEHGARMAAMDGATRNAGQLIKKVTLYYNKTRQ
                     AAITKELMDIVGGAEALK"
     gene            complement(22793..24310)
                     /gene="atpA"
                     /locus_tag="PK063_04810"
     CDS             complement(22793..24310)
                     /gene="atpA"
                     /locus_tag="PK063_04810"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000275 - mitochondrial
                     proton-transporting ATP synthase complex, catalytic sector
                     F(1) [Evidence IEA];
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HMZ96396.1"
                     /translation="MQIKAEEISSIIKEKIKGFDQQVDVSQTGSVIQVGDGIAKVYGL
                     DGAMAGEMLEFPGGLYGIALNLEEDNVGAVLMGDDTGIKEGDPVKRTGRIAEIPVGEA
                     LVGRVVNAIGQPIDGKGPINSQHSSRIEVVAPGVNTRQSVREPLQTGIKAIDAMIPIG
                     RGQRELIIGDRQTGKTAIAVDTIINQKGLGVFCIYVAVGQKRSTVARVVKTLEENHAM
                     EYSMVVAATASDPAPMQFLAPFAGAAIGEYFRDNGKHALIVYDDLSKHAVAYRQLSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDKLGGGSLTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLGSDLFYSGIRPAINVGLSVSRVGGSAQIKTMKQVAGTLRLDLAQYREM
                     AAFSQFGSELDKATQMQLARGVRMVELLKQGQYKPMPVADQVLSIYAGVNGFLDDVPV
                     DKVLQFEADLLHYVAQNHQDMRKDIATVGKIDDKVGGKLKEIITTFKQKMGYGGK"
     gene            complement(24313..24852)
                     /gene="atpH"
                     /locus_tag="PK063_04815"
     CDS             complement(24313..24852)
                     /gene="atpH"
                     /locus_tag="PK063_04815"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: protein motif:HMM:TIGR01145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000275 - mitochondrial
                     proton-transporting ATP synthase complex, catalytic sector
                     F(1) [Evidence IEA];
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit delta"
                     /protein_id="HMZ96397.1"
                     /translation="MIKTAVARRYAKALFELLDASSIEPARLALNGLGEAFTESSALR
                     HAVASPMFPEATKLSVLIEVATKLGCPPVVKRFLDQLVKKNRVSFLPDIADAFAKLVD
                     ESKGTQQVLVSSANALPATEQDRITTRLRDLLKRDVDVTFHTEPEHVAGLHIRLGSTV
                     VDSTVRGRLSAMQRVLTKE"
     gene            complement(25101..26183)
                     /gene="mnmA"
                     /locus_tag="PK063_04820"
     CDS             complement(25101..26183)
                     /gene="mnmA"
                     /locus_tag="PK063_04820"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HMZ96398.1"
                     /translation="MTRQTVLLGMSGGVDSSVAASLLVQQGYDVHGVTLQVWEHEDEH
                     VAVSKRWEERGCCKIGIAKFVAQRLRIPFEVVDRREIFQQGVIDDFVAGYAAGTTPNP
                     CVRCNERVKLRSLYALAQERGMDYVATGHYARVQQAGGQWSLHRALDARKDQSYFLYR
                     IQADWLPRLLFPVGEMQKSDVWKEAETLGLPVEELKESQEICFVSQGDYRTFLEQERP
                     ELKQPGAFVGVDGEVLGRHEGIAFYTPGQRRGLGIAVGQRLYVQKVVPESGEVVLCAE
                     EQLVQSDCQVGDISLFDRSIGRQAVDVDVKIRYATPPAAATLLPSTNGTVQIRFHQPQ
                     RALSPGQSAVFYQGDRVLGGGIIQRT"
     gene            complement(26216..26671)
                     /locus_tag="PK063_04825"
     CDS             complement(26216..26671)
                     /locus_tag="PK063_04825"
                     /inference="COORDINATES: protein motif:HMM:NF016408.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HMZ96399.1"
                     /translation="MWGETKKQSVAESDKFTFLGKGTSFKGIVTFDGTVRIDGRVEGE
                     VHTGGAVIVGESAVIKGVIAAGSVEISGRVKGSITAQQKVEIQKPGILIGDIQSPVIM
                     IEEGAHFHGMSNMGAEKWSEDEASEFGSPQDPGVRDLVAHRGKVKTQEP"
     gene            complement(26797..27273)
                     /locus_tag="PK063_04830"
     CDS             complement(26797..27273)
                     /locus_tag="PK063_04830"
                     /inference="COORDINATES: protein motif:HMM:NF016408.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HMZ96400.1"
                     /translation="MWIKDKPEGKRQAGQSEGSEMENLESTAPREGNEEINAFVGKGV
                     SFKGVISYNGTVRIDGNLDGEIHTEGVLLVGEDAVLTAKITAGTVVCKGKITGDISAR
                     EKVKLRAPAVVNAGVKAPLLAMEEGVVFNGTLEMSQTGTREPQGTSRGQGVKLVNG"
     gene            complement(27412..28263)
                     /locus_tag="PK063_04835"
     CDS             complement(27412..28263)
                     /locus_tag="PK063_04835"
                     /inference="COORDINATES: protein motif:HMM:TIGR00180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HMZ96401.1"
                     /translation="MEKKALGRGLDALLPTGRNTADPERGDVQELRLEAVVPNRFQPR
                     QQFSEVELAELTASLKQNGLLQPILVRRKGDGIYELIAGERRLRAAKLAGMQKIPALI
                     RNVSDQESMVLALVENLQRDDLNPMETARAYQRMLNEFSLTQEAIAQKVACDRSSVAN
                     MLRLTSLPAEVQHMIETDQLSTGHAKVILGLMTPAAQISLATQIVSGQLSVREAERLV
                     QGHAEAKKAGKRPVRAPLRSDLEERLQKRLGTRVDVQKGRRGGKIIIHYFSPEELDGV
                     VEQLLNG"
     gene            complement(28241..29017)
                     /locus_tag="PK063_04840"
     CDS             complement(28241..29017)
                     /locus_tag="PK063_04840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HMZ96402.1"
                     /translation="MARIIAVANQKGGVGKTTTSVNLAAALAIEGGSVLLVDIDPQGN
                     ATSGLGVDAMSLGKTIYNALIVKESITDLAMPTAVNGLSLVPANSHLAGAEVELVNME
                     GREQRLKEALAEVADRYDTILLDCPPALGLLTINAMVAAHSVLIPVQCEYYAMEGLGR
                     LMESIERMRQSLNPSLEIEGIVLTMYDARNSLARQVVEQIRGHFGEAVYQTMIPRNVT
                     LAEAPSYGRPALLYNMASSGAQAYLSLAKEFVVHGEKSPR"
     gene            complement(29089..29733)
                     /gene="rsmG"
                     /locus_tag="PK063_04845"
     CDS             complement(29089..29733)
                     /gene="rsmG"
                     /locus_tag="PK063_04845"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: protein motif:HMM:NF014575.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HMZ96403.1"
                     /translation="MEHDASQFEVSFRRFAAELGIPVDSSCLPFFSTYLSELKKWNKA
                     INLTAIHDDQEVLVKHFIDSVAGVKVIENMDKCELLDIGAGAGFPGLPLKFVLPQIEL
                     ELLEPSEKKGAFLRYVAGSLGLRHVTVVPSKLEQYVRRPTRRLFDYIVVRAFKVDESG
                     QMVADLLKPAGKVILYRAERVPRGFRLGGLALVQEVEYELPSGYGHRVLSVFSK"
     gene            complement(29823..31703)
                     /gene="mnmG"
                     /locus_tag="PK063_04850"
     CDS             complement(29823..31703)
                     /gene="mnmG"
                     /locus_tag="PK063_04850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HMZ96404.1"
                     /translation="MSEQCDVIVVGGGHAGCEAALAAARMGARTLLLTMDPDRIAQMS
                     CNPAVGGIAKGHLVKEIDALGGEMGRNTDQAGIQFRMINTSKGPAVRALRAQCDKKIY
                     RQVMQDTLRAQPCLRIRGGTVDRILTHAGAVVGIVTDSGQHIEARAVVLTSGTFLKGL
                     IHIGLSHFPAGRAGEASAEHLSDCMRDFGFEVGRLKTGTPPRLDRDTIDFSVMELQPG
                     DDPPPPFSYRTNRIPLPQVPCHLTHTNTQTHDIIAKNIDRSPLFSGVIDGIGPRYCPS
                     IEDKVVRFADKDRHQIFIEPEGLDTNEFYPNGISTSLPVDVQAAILRTIPGLKQAKIL
                     KPGYAVEYDYFPPRQLHNSLETKLVQGLYHAGQINGTSGYEEAGAQGIMAGINAALKL
                     RGDAPLVLDRSQAYIGVLIDDLITKDAREPYRMFTSRAEYRLLLRHDNADLRLMDLGH
                     RIGLIPDSVHHKFQEKRLAIEREVQRLKDTRPKLTPDVRRLLEEFEIGPVTPTQSLAE
                     ILRRQDLTYGKISSVFGGCEIEDADIMDAVQLEVKYEGYIKRQQQQIQRSQKFEHRAI
                     PESFDYDDVSGFSAEVREKFKRVRPASVGQASRISGVTPAAISLLLVAIERHKRQPLT
                     AE"
     gene            complement(31717..33147)
                     /gene="mnmE"
                     /locus_tag="PK063_04855"
     CDS             complement(31717..33147)
                     /gene="mnmE"
                     /locus_tag="PK063_04855"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF003661.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HMZ96405.1"
                     /translation="MLGALDDTICAIATPPGEGGIGILRISGFHALDVASHVVRLRSG
                     NALQDLPTHRLALADICADNTDVPAAGTKRTGALRFIDEALVVVMKGPHSFTGEDVVE
                     VQCHGGPVILDQLCRGLISAGARLAAPGEFTKRAFLNGRLDLAQAEAVLDTIRAKTAR
                     SLTLAQSQRRGELSRHVEEIRSELVVALAHIEAALDFAEEDISFVRQDELLRLLDVTL
                     QKLRRLLQSGRDGRIWREGAVVAILGRPNVGKSSLMNALLRSDRAIVTAIPGTTRDLL
                     EESLSIDGIPVRLLDTAGIRVTDDPVEVEGIRRSRLAWTDADLALILLDGSQSLSESD
                     RALLSEPDSTRALLIINKCDLPGQLSREDLDRACPGHSGILEISATLSIGLDELRETI
                     RGRLMPGMWESNEGVLVTNLRHTVAIERALQGVDQARQSVEAGRAGELIAMDLRIAAD
                     ALGEITGVITTDEILDRVFAEFCIGK"
     gene            complement(33169..34914)
                     /gene="yidC"
                     /locus_tag="PK063_04860"
     CDS             complement(33169..34914)
                     /gene="yidC"
                     /locus_tag="PK063_04860"
                     /inference="COORDINATES: protein motif:HMM:TIGR03593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0051205 - protein insertion into membrane
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HMZ96406.1"
                     /translation="MEKRVIVFLIVSLAVIIGYDYLLKGMGLLPPSEPVQVATNTQVA
                     ERQSAGSENASAQSVSPASSTQTSSPSAPGASDGGTGTVKEEQTIEVDTDLFRAKFSN
                     RGGVLKSWELKRYTTSTDQGPVPVQLVYAGGRFKGPLSLVTTDQSVTSDLGSALYQVT
                     QDISHLDSAHPTGHITFRYHDTQRNMDVEKELTFHHGSYVVDIAVRTQGLATPVDVTL
                     GTNFGIVEWGEGFIGLMGSASLVDDKVLKETPDGEAERKGDVKWSAIQDKYFLSVLMP
                     KKAMSALAKKEGDKLVSAGVRFPAPTPGSTMTMQLYAGPKEYDTLKGLNVGLEDTIDF
                     GWFVFGSWALVKAVAKPIFYVLRFLYEFTHNYGVTIILLTMLIKLMFVPLQYKSYKSM
                     KQMQVIQPKVLAIQNKFKDDRERLNKELIKLYKDHRVNPVGGCLPMVLQMPVFVALFN
                     ILYMTIDLRQAPFMLWIKDLSVQDPYYVLPIIMGATMVIQQKITPTTMDPTQAKIMLF
                     LPVFMTFLFVNFPAGLVLYWLTNNTLTITQQVVTERLFGKKWQVVPEGADAAAIEDSK
                     EQKSNGKRRNASATE"
     gene            complement(34960..35169)
                     /gene="yidD"
                     /locus_tag="PK063_04865"
     CDS             complement(34960..35169)
                     /gene="yidD"
                     /locus_tag="PK063_04865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HMZ96407.1"
                     /translation="MRYFCIGLLSVYRACVSPMLGPACRFHPTCSVYAQDAIERYGLL
                     KGVAMAGWRLLKCHPFHPGGVDPVR"
     gene            complement(35166..35537)
                     /gene="rnpA"
                     /locus_tag="PK063_04870"
     CDS             complement(35166..35537)
                     /gene="rnpA"
                     /locus_tag="PK063_04870"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: protein motif:HMM:TIGR00188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HMZ96408.1"
                     /translation="MTAGQASASFFLKRSGDIQLIKKNGRRVSTGLFNLQICPGTMPQ
                     DTMMGIVIGRRFGTAVRRNRAKRLFRELGRAVRPTLSAGHAFLVFPKRQCLNVPFVEL
                     QSVWRSTLQRQRLVRVGDPSS"
     gene            complement(35717..35854)
                     /gene="rpmH"
                     /locus_tag="PK063_04875"
     CDS             complement(35717..35854)
                     /gene="rpmH"
                     /locus_tag="PK063_04875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HMZ96409.1"
                     /translation="MSFTFKQPSNLKRKREHGFRKRMSTKNGRKVIARRRAKGRARLT
                     V"
     gene            36348..37496
                     /locus_tag="PK063_04880"
     CDS             36348..37496
                     /locus_tag="PK063_04880"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF015679.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA];
                     GO_function: GO:0071972 - peptidoglycan L,D-transpeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HMZ96410.1"
                     /translation="MSRSRYICRIATRVTLVALLSMSLGGCVETVPEELVESIESLDR
                     DLSTLRASDVNPAAYSKFSRQWIALQGRIRSEENIVRWPWEDNELETDLEALQVEGTQ
                     LLSDVNSRIQAQRTTAETKLAKIEQRLRLLNSRVGDIGSRVVLGEHPVETEVHVKQAR
                     LFLEQGQFEHSIQASERAGRILLTQTALLTNELGRYADDDLIAAWRESAQRTIDWSRT
                     HRAQAIVVSKADRSLTLYKNGRKVLTYPIRLGSRGIRAKQHYGDGATPEGEYRIQRKR
                     GPGQTPYFRALILDYPNIDDRRRFEEAQKAGLIPKSQHMPGLIQLHGIAQGISDQPYG
                     SIVLDNPQIAQLFDQVAVGTPVNIVGALESQNSISLVLADLGDQEEET"
     gene            37684..39384
                     /locus_tag="PK063_04885"
     CDS             37684..39384
                     /locus_tag="PK063_04885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HMZ96411.1"
                     /translation="MPIRPKVTSLLDTQTLATTFDELASSRAIERILMRDHTLWKPNP
                     TEIDNRLGWLTVLDHMQDGLSDLRSFAQAAREARTTDVVLLGMGGSSLGPEVLRCTFG
                     SSKGAPRLWVLDSTVPGWVRQVTDAIQPARTLFLVASKSGGTIEVMSLFAHFWELVHR
                     TKGHRGGAQFVAITDPATGLEELARERGFWRTFTNQPDIGGRYSVLSYFGLVPAALLG
                     LDVGKLLTRALAMRESCRHTVAKENPGSALGGLMAAMAKSGRDKVTLLTSPALTSFGL
                     WVEQLLAESTGKEGTGLIPVAGEPFASPAAYGADRIFISLRLRGDRNASLDRTVSALQ
                     RAGQPVYSIPLKDRYDLGGEFFRWEFATAIAGHALGIHPFDQPNVQESKDNTGRVLKE
                     VETQGKLPSIAVLPPKQALTQLLEQMGSNRYLAILAYTTPTTQVEAALRALRKALMVR
                     YHVATTTGYGPRYLHSTGQLHKGGPNSGLFLELVDTMKPDLAVPEKFYTFGTLAQAQA
                     LGDLQSLHTHQRPAVRIALGPNPVRTIRSLVTFLTPAKATRRKSVPKKRTTSTRRSRR
                     "
     gene            39386..40156
                     /gene="pgl"
                     /locus_tag="PK063_04890"
     CDS             39386..40156
                     /gene="pgl"
                     /locus_tag="PK063_04890"
                     /EC_number="3.1.1.31"
                     /inference="COORDINATES: protein motif:HMM:TIGR01198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017057 - 6-phosphogluconolactonase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconolactonase"
                     /protein_id="HMZ96412.1"
                     /translation="MAHPPERYIFADAQEVVRAAATLFVTVGQQAISKRARFLVALSG
                     GSTPKALYMVLASKEFATQLDWNKVHFLFGDERAVPPTHQDSNFALANTLLFTPLNIS
                     ATHIHRMRGEDSPETAAIHYENLLRGLTATTSEQWPVLDLVLLGMGEDGHTASLFPGT
                     PALSEPTRWVVPGLAPQGTRSRITLTLGVINHASVVLFLVTGLNKATVVRRIFESRAD
                     APDAYPAARIRPETGRLLWYFDRAAASALTEATDELSS"
     gene            40165..41250
                     /gene="glk"
                     /locus_tag="PK063_04895"
     CDS             40165..41250
                     /gene="glk"
                     /locus_tag="PK063_04895"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: protein motif:HMM:NF014715.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucokinase"
                     /protein_id="HMZ96413.1"
                     /translation="MILAGDIGGTKTNLALYEWTSGRVEPVREDSFHSADYKSLEEII
                     DEFLSTPLVKPALENALTEESVDLGSDVAAETAPVVPEPITLTAACFGVAGPVIDNRC
                     RTTNLPWFIDGAALGERFVIPHVRLLNDLEATAHGLLHLTTDEMVVLNAGAPPKKKQA
                     LALIAAGTGLGECILYWDGTRYRPMPSEGGHTDFAPNSDSEIELLRHLRGSYLHVSYE
                     RIVSGPGLHAIYEYLRDTKKNEPTWLAEKIKVGNPAAEIAEAGLKGQAEIATQALELF
                     ASVYGAEAGNLALKALTLDGVYVAGGIAPKLLKKLQDGSFMRGFTNKGRYKRLMNQIP
                     VKVVMNDKTALLGAASVAAQLTLPPSL"
     gene            41247..41951
                     /gene="rpiA"
                     /locus_tag="PK063_04900"
     CDS             41247..41951
                     /gene="rpiA"
                     /locus_tag="PK063_04900"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HMZ96414.1"
                     /translation="MTTTSCDLDSEKRQAALKATEFVHDGMVVGLGTGTTSKHLIIAL
                     GERVRAGLNIQAVPTSHDTAALAKQSGIPLIESDNAWMIDVAIDGADQVDPALNLVKG
                     GGGALLKEKIVAAAAKRFIVMVDHTKLVPALGGSFPLPIEVVPFGWGSTARHIEAVSG
                     GRAVLRQRNGDVFQTEAGHVILDLHMPIIDDPAALEVELNQIPGIVETGLFIGRTSIL
                     IVGHGQGTDVTHAPKP"
     gene            41948..44722
                     /locus_tag="PK063_04905"
     CDS             41948..44722
                     /locus_tag="PK063_04905"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF023266.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HMZ96415.1"
                     /translation="MTRPQGDLPVTRRQAAALAVRAATHAALWLGAWPGIASLVFVPE
                     ARSQTTSTHNQQHPHNTMTTSSAIADPYRLPRHVIPTYYDLRMEPDLPSHSFTGHEIV
                     TLTVTEPTTDILLNATELEVSAATLSGEGQPPRTGTVRMDDEHQRCHITFPAVIPPGV
                     WKLSLAFRGTLNDKLRGFYRSSYKDDRGIAHSLAATQFEATDARRAFPCWDEPHFKAV
                     FAVTLAIDPALTAISNTRIVDERLENGKRIVRFAESMKMSTYLVAFIVGELVSTAPIM
                     AKQTPVRLWSVPGKQHLTPFGHEIAVYSLNFLAEYYDIPYPGDKLDLIAIPDFASGAM
                     ENLGAITFRETALLLDQRTATHAEQGRIADVVAHENAHMWFGDLVTMAWWNGLWLNEA
                     FATFMEMLVVDAWKPEWERWTAFGMARAAALSVDGLLSTRPIEFPVRAPKEAEAMFDV
                     LTYEKGASVLRMLEQHIGPTVFRDGVRHYLHAHAYGNAETTDLWVSLGHASKQDVPAL
                     MNEWIFSPGYPLLSLSVESRSTLMLTQRRFMYADDSSTAPSGTASPRWQVPVQLRINT
                     ARGTETRRVLLSERENRIPLPEGWTSILANEGGHGFYRVRYSADLLSALQKDGLNTLT
                     AVERFNLLNDTWAATVAGMVSSADYLALTEHFRSEQDPHVWAVMLGSFSTINHLLEEE
                     DRPLLAALVRDRVAPLFQQLGWSPHADERDLVKELRGDIIRALGTLGRDETIQAQARE
                     AYTAIQQKSRPIDPNVIPALVSILAFTGDEARYEEFSGRFRQATTPQEERRYLFSLAA
                     FRRPELLERTLTKTLTDEIRTQDAPFLVSSLLQNVYIREKAWEFVKTNWERMDKLFPK
                     SGLRRMCGGLTGLSTPELEQDVRHFFTSRKIDLGGKTLEQNLEQLHIAVQFREREREA
                     IRAVLARRST"
     gene            complement(44751..47423)
                     /locus_tag="PK063_04910"
     CDS             complement(44751..47423)
                     /locus_tag="PK063_04910"
                     /inference="COORDINATES: protein motif:HMM:NF024116.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HMZ96416.1"
                     /translation="MRPFWFILAWRDLRSSWRHFVYFLACIALGVGAVVGVSLFSANV
                     ERAVLKEARGLLGGDLEIRLSRPLGGPGSTVLKDLTGRGIEVTRVDELVAMVARVDRR
                     EGGMDVTQLVELKAVEPRYPLYGVVRVEPDRPLTELLHPAGDRCGTICHGAVVQQALL
                     IRLGLGVGDAMKIGQASFRITGVIHTEPDRMANMFSLGPRVLISQEGLAAADLIKPGS
                     RMRERHLLRLPASMALSPLLHELRGRLGVESARVSSYRDAQPQLKQFLDQLARYLGLV
                     GLTALFVGGIGVALSIHAFVREKLPSIAILKTVGADTATIIYSYLGQAVGLGLLGSLG
                     GIGIGVALQTVLPQAVSTLLATDVLQQVEFTSVLSLSAVAPIGKGLGLGILTTLLFSV
                     WPLLTIRDIKPAAIFRREVERVGAPLVRREKALWKRAGQVMTADPLRTVTAAGIGIGL
                     ASLSMWQAGSLTIGALFIGGLVIAIAVLTLGAQALLRGLRALPVPRELSLRQALGNIQ
                     RPGGQTLGVMVSIGVGVMVILAIALLQHALVRQVGENRPSDSPTFFFIDIQPDQAQAF
                     GELVHRRTGDFAPDLTPLVRSRIHAINGRPVTDEREAQQDEPPAQSKEEKRKSWYVTR
                     EYVLTFLDQVPKDNKIVKGAWWKPGQVFSKPQVSVEEEAAKSLDLDVGSLLDLNIQGT
                     ILQAEVSSIRKVEWGNFSTNFYMIFSPGSLDAAPMTYVATVRVAPQDEVAFQSAVVAA
                     FPNVTAINIGEVLNSFARVLDRLSLAIRGVALFCLMAGALVMAAALAATRYRRLYEAV
                     ILKALGATRGLIARSFAAEYALLGCVAGMIGVALASLFSWAILRYILELPWALELPVL
                     GIGLGCTVLLTLLVGFLSTYRILGQPPLTVLRHE"
     gene            complement(47420..48127)
                     /locus_tag="PK063_04915"
     CDS             complement(47420..48127)
                     /locus_tag="PK063_04915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ96417.1"
                     /translation="MMIATQQVTMQLEAGGETVRILDDITLEIPEKQTVAIVGPSGSG
                     KSTLLGLIAGLDRPTSGTIWLNGREITRLNEKAMARLRLANVGYIFQSFHLIPTLTAL
                     ENVSIPLELAGDRHARQRAMELLEAVGLGHRVSHYPVQLSGGEQQRVAVARAFACRPP
                     ILLADEPTGNLDSHTGQQVIQLIMALHRDAGTTLVLVTHDQQLAASMERVITLRDGRI
                     GSDQFMASSYDESGDRL"
     gene            48417..48989
                     /locus_tag="PK063_04920"
     CDS             48417..48989
                     /locus_tag="PK063_04920"
                     /inference="COORDINATES: protein motif:HMM:NF012863.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylesterase"
                     /protein_id="HMZ96418.1"
                     /translation="MAFGNSLTAGLGVSPEHTYPAQLQKQLDTLGLHYQVLNAGVSGD
                     TTAGGLRRVSWLLAGKPSVVILELGGNDGLRGLSLPETRSHLDTIIKRLKEARVQVIL
                     AGMKLPPNYGEEYTTQFEAMYRDLAKAHALALIPFLLEGVGGDQKLNQADGIHPTGEG
                     YRIVVQNVLQTLLPLLKSGESHSPTSKKKA"
     gene            complement(49052..49228)
                     /locus_tag="PK063_04925"
     CDS             complement(49052..49228)
                     /locus_tag="PK063_04925"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96419.1"
                     /translation="MNKLIAGVLGGIGALQATNALANVSEGPPDYSGITGLYYVLIAL
                     ILAFGVYDTFFKKS"
     gene            complement(49370..50182)
                     /locus_tag="PK063_04930"
     CDS             complement(49370..50182)
                     /locus_tag="PK063_04930"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96420.1"
                     /translation="MISSIVEPNAFQIGRQYQTERRVQLTDASDTEFTSSVMGNSGLY
                     EQTIRLHNGHLEAKCSCTLHEQPICRHGVAALLEYQRWSKARVVPRARPAAPRLEAER
                     ATTKSAPSGDVKLSELNQFSDWMQRVVQAIQSGQPVPAQPDIEPGLVSTWTRIIQQLD
                     ERRRESEVAQIELDTDIRNREAVVARLTQDLEASAKEAKSLQVICRDLQREVDQHKAS
                     LSKSTELSRHVEQFEGEVRAIAGLLTEKGRRLEGLSDTCRDVATMLKALGKV"
     gene            complement(50453..51469)
                     /locus_tag="PK063_04935"
     CDS             complement(50453..51469)
                     /locus_tag="PK063_04935"
                     /inference="COORDINATES: protein motif:HMM:NF016103.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChaN family lipoprotein"
                     /protein_id="HMZ96421.1"
                     /translation="MRTSLQHLREKVLNNLSGVIAILVLVVALGGCQAAGPVPRVTPQ
                     VWDAWSVGQILDAKTGHVVSTAEWLEGLAGYDVIYLGEEHHNRSHIESALTVLRTLVT
                     RGRRPVLAMEMFGWEGQPALDAYLETKESARPEFLERVGWKQNWGGAFEDYEPLVQFA
                     KDQRLPVLAMNPPKTLIRQVVKLGLAQAKEQPEWRQRGMEQETIVDDPAYRSRILSQL
                     QACHGGGAPEDYQTMYDASMVRDEGMAKTVAAAVNRVRAAGDPTQGPVVSYTGGGHVQ
                     YRLPVPNRVARRVEHGLKQVTIYMATLEQDRAAELYQSMQEGIADFVWLTPPGSQGAP
                     RRCR"
     gene            51603..52931
                     /locus_tag="PK063_04940"
     CDS             51603..52931
                     /locus_tag="PK063_04940"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96422.1"
                     /translation="MPVDSDSLAAFRKQVTSARSLDAPLWEASRHLVHSADWPATRTA
                     LVKAIHASSIPDGLKQTLVAALPVDLATEDRTSSAVLLKQLTGLPLTKALRALCVFFQ
                     VGRPAMAKWPLPTVTPDTIDRFVQTHHNPFDVLLEQLPASLLDLGAGDLSFAEELATI
                     YEPPLTAQHRPLLLHCLDRLDPSSQLGGPLHAPPLRLNRLRSKPGLEFRFYGDQDMFA
                     LDSLERDQRLAARYLIVTCWAPATPTFAYEPTRLSARCLAEELRRTKGDSRQIRHGKE
                     PALEVSHAGRNLLFPPWKFDIRGPLALLELMASRAALCVLGAVDSQVCWEILSQLIDD
                     PRVRPADVVLSAETLPAIFGETYRQLSALPVGGSCLLSDLTPLRKSFPSVLHTSPGHP
                     APYRFRQVKIQRGALFAGLPASSTARRFQGMSEETPPWLLTLVPEPVAIS"
     gene            53086..54027
                     /locus_tag="PK063_04945"
     CDS             53086..54027
                     /locus_tag="PK063_04945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HMZ96423.1"
                     /translation="MNSSQSIKLLQDNIAQVIKGKARAIELAVVCLLARGHLLIEDVP
                     GVGKTTLAHSLARSLDCSFKRIQFTSDLLPSDIVGISVFNRQKQAFEFMPGPLFAHIV
                     LADEINRTTPKTQSSLLEAMSEAQISVDNQTYPLQQPFMVIATQNPAEYHGTFPLPES
                     QLDRFLMRLCIGYPTPEEEKKVLDRPPSLHPANEIEPVLNAQHILDLQAQVDKVRMED
                     SLMDYLLAIVLATRQNPLFSLGVSTRGALALSKAAKALALARDRTYCLPEDIKELAPA
                     VLSHRVMLNRSQGARTKSVEHTERVIHDILESIPVPV"
     gene            54100..55242
                     /locus_tag="PK063_04950"
     CDS             54100..55242
                     /locus_tag="PK063_04950"
                     /inference="COORDINATES: protein motif:HMM:NF013998.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HMZ96424.1"
                     /translation="MAFITLRTWLHQLSRHRAISVTTEGVRFLLLTLAVGIAAVNTGN
                     NLFYLLLAMMLSLIVLSGFLSEQCVRRLEFHRHLPDTLFVNQQATATLWIANRKSHLP
                     SISLRFLDVAAGQDHECGIHLTHLAPGASTLRAYPLLIKRRGRCQLDGIRVVTPFPFG
                     LFHKKAFYPLEASVIVCPALIPLPPMQVQALHAIGHDHALARRGHGNSLYNLREFRPG
                     DDSRAIHWMTTARTAKLMLKETEAEDQRIITLAVFTVAADAEVTTFERALSIAASLID
                     QLLKSGVRLRLLLGDQQEVMAEGNESPLHLFHALALCERRPVDDSTAVQQALISTLVR
                     SQDGPTLLIASWADPALQDLFPGVDQILTPHTHKDLFDADGSGLPA"
     gene            55214..57415
                     /locus_tag="PK063_04955"
     CDS             55214..57415
                     /locus_tag="PK063_04955"
                     /inference="COORDINATES: protein motif:HMM:NF023418.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3488 and transglutaminase-like
                     domain-containing protein"
                     /protein_id="HMZ96425.1"
                     /translation="MPMDQAFRLSSILLAGTGFASLTLAMALPLWLLVLAAGAFGMAL
                     LRVQSSGAISGAIGHLRFSALTWNIFLLLAFAGFWIDLFLISQEILPAGIHFLVLLLV
                     NKLSNLDQRRDFLHLYAISLIALLASAALTTQIWYAPFFFIYLVIGVWTLLLYHLLQE
                     REELTEPEPGHAHAEPSPVPLPRLTARFFWTTNAMAASAFGLTLLFFFLIPRVGVGFF
                     QNNHGENLRTTGFSEHVDLGVMGPVKQDPSIVMRVELPERTGHDAKWEPLYLRGVAYN
                     RYDGKSWSNSLPHRRMLTELPEGTFTLRTLASKPSPPARQLKLEILLEPLDTTVLFGS
                     PFPTAVKGHFLSLQSDLMGSLYLPFPLHTRSQYTVYSSPTSLNAAEKKSAALIYPDSI
                     LQQYLQVPAVNEQVLELARQVTRPATSVAQAVAMVHTHLLTHYRYNLDVPSLQSPHPL
                     EDFLLTRKTGYCEHYATAMVVMLRSVGIPARLVTGFLATEWNEFGGYYTVRQRDAHAW
                     VEVYFPQSGWITMDPTPPSPNAVGPTWWQSANSAMDSIRLQWDRLFVHYSAHDQFTVV
                     QGIREGGEAVRAGFSETLSALSAQGVAIVSHMVIRLTPSGVPHVVIALVLAAAAVYGG
                     IVILRRFRTRTTPRSPFSTQQQTVIALYTTMLQCCAQQGITKPASATSVEFLEQIRTR
                     WGEAWPLVDSVTRLYARVRFGEAALTEADLATAEVQLRTLRLLKRKTADSQ"
     gene            57504..58103
                     /locus_tag="PK063_04960"
     CDS             57504..58103
                     /locus_tag="PK063_04960"
                     /inference="COORDINATES: protein motif:HMM:NF025024.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2OG-Fe(II) oxygenase"
                     /protein_id="HMZ96426.1"
                     /translation="MIKELLDAERVFVIDHFLSEEECAALIRRSEAAAYEPGTVGGVV
                     NENFRNNERVIVDDESLASNLFQRAQPFLPAVLDGHHLVGFNERRRFYRYQPGQTFQP
                     HRDGSYLRMKTGDKSEVTMMIYLNDGMVGGETKFYASADHAFLQPPAPYLSVRPKMGM
                     ALVFLHAIWHEGAVVQSGLKYVLRTDVLYGLHSAESRQG"
     gene            complement(58462..59946)
                     /locus_tag="PK063_04965"
     CDS             complement(58462..59946)
                     /locus_tag="PK063_04965"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HMZ96427.1"
                     /translation="MTHRMGKGSSPIGLKAFILFQIFRSFDKPLDMISLVSLPVALCG
                     LAASFFSFIVIFYRLQHQGIDLWHAGGLLFIIAVFCLACISLSAHYRHTRRIASKAFT
                     LQLTATGIALALLFLGAEVMIRVVAEQTPEETFVGDTVLLPREWQRVQAHRLADWERS
                     RQQSTIIEPDATLGWTIGPNRKEIGIFGEMYFSNAYGLRTLANETDPKATAPALRIAI
                     SGNSYAYGLDVTYDETWGHQLESRIGQHVQVLNFGVPAYGLDQSYLRYLRDIQDWHPD
                     IVILALISHDLVRSGLVYYLIGFQGGRVPGAKPRLSVVGEEPFALNLPLPSPERIYST
                     SSIEDLPFVDFDIAYRPADWKWHLYQYSYLLRFAVSWNPTSLWSPYELAPDVERVDKA
                     ILKSFVDTVRATGSTPLVVFLPEYGEFRHSVRSPSEQQLLGRRVLQEAGVKFLDLTAC
                     LELVNATSRFTLGWHYTAAANSAVAECLLDEVSRLVGVILEHKS"
     gene            60305..60688
                     /locus_tag="PK063_04970"
     CDS             60305..60688
                     /locus_tag="PK063_04970"
                     /inference="COORDINATES: protein motif:HMM:NF012798.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HMZ96428.1"
                     /translation="MSVNASDCKHEESRSSVHKTHAHVSANGVPGNLTRAFRLGATKA
                     ALSDFRFHDLRHTFATRLAQAGVDLYKVQRLLGHKTAAMTQRYAHHSPESLREGVLIL
                     ERVHPQISQNYHNEGGTVGECCASA"
BASE COUNT        13307 a        18196 c        16355 g        12890 t
ORIGIN      
        1 cgggggccat tccgctccgc cccgcagcct gccggcatgc ggcgcggacc ggcttcgcct
       61 cccggccacg gacgacggtg ttgttctgaa cagggctcca ttcggagtgt tgtcgcattc
      121 ttgcgatcgt ttcggtgcat gcgtagacct tatgcaaacg cctcccccgc agtaaagaac
      181 cctctagagg acaggagggg tcacgagggg acaaatcgag gacaaattat cgggaggacg
      241 aggcaagaag ggaagtacgc agaaggaggc atatgtgcgc tttcgtgcgc tcagagcggc
      301 aattgtgagc accgttcaga gccggaacat gcagcaacca aaaatcgacc agttttttga
      361 ttgtgcgcga aaaaaaagtt tggaaggtaa tcccggcgtt ctgggatagg atcagagtga
      421 cgtgacaccc tgacgccgac gacgatcgaa gcgttgacct atacctacga caagggtgga
      481 aaccggatca cgcaattgcg acagaacgcg gccggctcca atcttcccac ggccgtggcc
      541 gccgccaaca ttgcctacga tgcggcgaat gaactcacac gttggaatag cgcgactacg
      601 aatctcacgt acaacagcaa tggcaatcta gcgacggaga cgcaaggcgg gttgacgacg
      661 acctacacat gggacgctag aaacagactg agcggaatca gtcggacagg tttgacggca
      721 agttttgcct atgacgcatt gggacgaaga aaatcgaaga caatcaacgg ggcgacgact
      781 gggttttggt acgacgggaa cgatgtctat gccgaaatca tgggggccac accctcggcc
      841 acatacatcc gaggtctcag catcgatgag ccctacatcc gcaaaggcgc caatgatgag
      901 ttctacgaaa ctgacgctct tggaacttct attgcactta ccaatgccgc cggggcaagt
      961 cagaccacct atacctacca gccctatggc gtatctacgc aactagacac acctagtagc
     1021 aatgcttttc agtatacggg gcgggataat gacgagacag ggcttattta ttatcgggca
     1081 aggtattacc atccaaatat gcagcgcttt gtcactgaag atcccctacg atttcgaggg
     1141 ggagaaaaca acttctatgt ctacacaaat aacagtccaa ctcaggcgag cgatcctttg
     1201 gggttgttta tgattgactc tgccacatgt cgaaataagg acacccgtgg tttcattcga
     1261 tcaatggcag cagttgctta cgataccgca atgaataagc cgaattgctt gaactgctca
     1321 cagcgacaag cgttcaaggc cagatgggag gatcttgtaa taagttgctg gccatcgaat
     1381 tatactccca acggaaggcc tgcatgtggg tttcaaaacg attcactagg gacaaatgtg
     1441 atatggctga ctccccaagg actgaatgcg caaggatgtt ggagtgtgcc tggcacaatc
     1501 tttcacgaga ctctccatac actcaccagc atgctagggc cagaatatgc aggtgaacag
     1561 attgtcagag aattagaagc caattgtttc accagaccac cgacaatgaa gtgaggacag
     1621 taagaggagc tcaatgactg ggatgctgat ggctgtccga aatctagcct ttttactgct
     1681 agtcgttttg cccctttcgt atgtcgacaa ctccgatgga aaaattgtcg aagaagattt
     1741 ggaagctatg gttcacgagt ctaaacttat tgtgctcggc aaggtcgcta gcgcggaatt
     1801 cactggtcag atacttactg atgaattcaa gatcggcaaa tggagtttgt tcaaggctgt
     1861 gattaaacct gaccttgtca taaagggacg ccttcaacaa gatgagctcg acctctatta
     1921 cattggtgga atgagtactg aagcaagatt taatgtgaac gataccagca tatttttcgt
     1981 cgatgaggat gatcaaggcc gtctcgccac cgtgcggggt tatgcaggga aagtcgatat
     2041 cacgcagcag gttgccatgc cggtagcaat tcgcaatgaa gagaatcctc aaccgcttga
     2101 tgcgtttatc cgaaagatca gggcgattgt agagcgtgct cgataaattc cggtccaatg
     2161 cctggtagtt atttactttg tgaagctgga ggtgtcgtgc agatacgatt gctggttttt
     2221 ctcggaacca ggatcttctt cgcttttctg tgtctttcgt tttgcaaggg atatctagtc
     2281 ctggcggacc aatccctata cctttacgat gatcaagagc gcctaatcgg tgtggcagac
     2341 agtgccggcg caaccgccat ctacacttat gatccggtgg gcaatctcct ctcgatcgac
     2401 cggttttccc ctccaggcag cggaattgga atctatatag taaatcccat catggggccg
     2461 gttacacagc tttgccgact tcaagggtac ggatttgatc gatgggcaga tcgtaaggaa
     2521 gcaggatcgc ttcgttagac tgaccgtttc cagctttcga cgatgaggcc aggaatgcgc
     2581 tggaagtgcg cgaggttgtt cgtaatcaac ggacgttgcg cgtccaaggc agtagcggca
     2641 atgagcaggt ctgcatcggg cagcaaagcc ccctgtcgat ggagatcgcc gtataacgtc
     2701 gccgcacgct cgacgacttg gtcggtgatc gggagaatga gactggcctg gcagagcaac
     2761 gtgaaggctg cctcttgagt ccgtgcctgt ttcgccttca gtccccgcag gagctcatag
     2821 cgcgtaatga ttgagaaggc cagccgctgg tgctccgtca gatagctccg cacacgctgc
     2881 acgacgagag gatgttgctt gagcagttcg gagagaatat cagtatcgag gaggacagcc
     2941 ggttgcggca ttaggcagcc ggctcacgga agaagtgctg ccgatccaat gcgatggact
     3001 cgacctgcgt gatctcgtcg gcactcagcc cttgatagac ctgcgctgca cgacgcagaa
     3061 tttcgtccgt accgagcgca aggtcggtat cgactgtgac ctgcacttcc gcgtcatcgg
     3121 ccagggaaag aggttccaac ggctgtagca ctccgtcatg gtagcgggct ttgattgttt
     3181 gtcgcatcgt cgaaccctcc tccgcactcg cccatctgaa tgagtcggct agctgcttcc
     3241 attctactca aaccggactc aaatctcacc acttgtcgaa agatcgtccc tcaccctgcc
     3301 acacgagctg gggtgtcgct gttcctcagg cactgtctca gtgaaggggt tcaccccagg
     3361 ggttcacccc agccgattgt gctaacggtg tggcaaaatc cagctgagca tccagcagga
     3421 actgtaaggt cgccgctcag ttagcggcca agtagcatga ttgatcgtca agactcagcc
     3481 accggaacta gcctacattc aaaacacatt attgatggga gcgcgccgtg gagggggcgg
     3541 acactgaaag cggccgccgc tgattattca atttcagctg atcaaatatc ccttatgcga
     3601 tagtatctag ggtatgcata gcgcgttgac cacacccacc gagatcacgg catcgactcc
     3661 tcgccatcaa tgcctgattt ataagggctc accagcgacg catttttctg ggctctcggc
     3721 tgtcattcgg caaaaactta ccgagaatta tcgctgcctg tatttcaata cctcggccat
     3781 gatcgctgcc atgcgcccct atttgctggc tgcgggaatc gatattccac aagaagttga
     3841 aagaggccgt ctcgtcttat cttcaaaccc gacccatctc accgatgggc atttcagtat
     3901 tgatcgaatg ctcggaatgc ttgaggaagg attgaaccaa gccttgcagg acgggcatgc
     3961 cggtttctgg tgtacgggtg acatgacctt ggagtttggt ccagaaagag atttttcaaa
     4021 gcttctggat tatgaatggc ggctggaaac atttcttcaa tcacatccgg ccctctccgg
     4081 tatctgccaa tatcatgcgg atacgctccc gaatgaagta ttacggcaag gcctattggc
     4141 tcatccgtca ctctacatca atgagacact ctctcggctc aatcctcatt acgtagatcg
     4201 tgaatcgttc acggccgcaa cataccatga ccctgccctt gataagacca tccgagcgct
     4261 gtgcatggtg ccggatgcgt taattttgaa tgccctccct cccggttatc tccactaaag
     4321 acaccacata ctgatctgat tcgagtttct tctaggaggc atgtgattcg cttgatgaag
     4381 aaggcgtcag cgaaccctgg agccatcagc ctccctccct gtaagcattg agacatttct
     4441 tgagatcgag gcagctctag aggctcgtgt tggcagctgg acgctttacc gcacgtatgc
     4501 caatgacgag ttcatagtcg cggtcccaat ggtctaactc ggcggtggtg agctctgtgg
     4561 agtggagtcc atgcaaactc gcaagggagg atagcacgtt gccgtaggtc gtgatcgtga
     4621 tgtcttccgg acgaaacact tgttcaaaga gtcgacgggc cgacagggac gtaaaccgcc
     4681 aaaactcgcc ccaattgtcc atgtcataac gcgcgatgtg actgatccca ggaacgatca
     4741 ccaataacac tcctccgggg cgcaaaatac ggccgagtgt tctgagcgcc gccggaacat
     4801 caaaaataaa ctgcaacgtg aaagtcagaa tggcgcaatc gtaagtgttt gagggaatct
     4861 gtttggcatc agtgaggtca gcctggatgg tcgtgccccc catacccgga ttcacgttga
     4921 ggatctccga gagggtcact ctctcgcccc cgaattgtcg ggtgtagcga tcatcgccga
     4981 tttccagcac ccggccgcga atatccgcct ggtaagcagg gagaaaatgg tcttcggtat
     5041 agtaccgatc gatggggcgt cctgactgcc agccgaaatc acgccgaata ggatggacgc
     5101 gccggagaga atttccccac ctccagtcaa gccctacacc accgtgttcg tgaagcaacg
     5161 tgactcgggc ctgctgatag aacacttctc cgatgagccg cctgatgaat gttttaaatg
     5221 gccatgccag tgcagagatc aacagacttc gaagcgacaa atgtccatgg ctgggcggtc
     5281 cgctgcgtga ttcggagaaa ggggtgtcag gcaagatatg gctcctcaaa aacgggctag
     5341 ctgatgcatc ccatttacag gattacatct gggccctgtt ctcgactgcg accactaatt
     5401 ttgcgacaca atccggcaag gcgtagaagc tgtacgatgg cgatagggtt tcgcgtcccc
     5461 agaatgtgtg cgggaattgc gcatcagctt agcagccggg cgctgacgcg ctattgtcaa
     5521 cggccgcccg cttgcccata gtgccctagg aacggtgttg ttttacctag gcgaaacccg
     5581 ggcatgcccc aatattgaca gagatatctt cctgaattct gacagtggaa atgagtatat
     5641 acggcttcac cctcttgtgg aagccatata agttcagatg tgaaactacg atcacgccaa
     5701 tcgatgaacg agtacgggat gttcctttaa atgcttttat ttcgagaggg atgctcagca
     5761 gtttttagca atctgcgcgt tggtcggcgc tagcctccca gtgcaggttc atcacagacc
     5821 cgcgaacagc cgacctcggg gctccgccct ttcgcctccg atagtcttgt cgcaggtagg
     5881 cccctggaag cctgcagcct tttattgctc gttacttttt cgctgcaggg cgaccatggc
     5941 gaaaatccac ggggaccgac aggggctcca gctgcaatcg tttatgatgc atggccagga
     6001 gcaccgcttt tcccggagtg gcttgataat ctccacggaa gctcttgtag tagatcatca
     6061 ctttccggac gtagtcgcga gtttcgggat agggcggtat ggcgtgatat cgttctactc
     6121 gccgttcgcc ggcattgtac gccgccacag ccagccggat gttgccgtta aatcgatcca
     6181 gtaaataccg caaatgccgc gcgccgccgc gaatgttatc gcccgtatca tataagttgt
     6241 gcacaccgtg acgaatggcg gtttcgggaa tcaactgcat gagtcccacc gctccagctc
     6301 gtgaaatgac ggtgggatta aaatccgact ctgccttgat tacagccagc agcagggctg
     6361 ggtgcaggtg gaactgccag gcatagcgtt caacggcatc ctcgacttct tcgactgatg
     6421 ctcgatgtga caatcggcta cgctgcaact cagccggacg aaagcgtcca tccgtcggaa
     6481 cattcgtcat ctcgaacacg ccgtttgctc ccacatagcc gtagatgtcg ttttccgcag
     6541 aggcggaatc ccccacaacc aacaccccgg caatcgccaa tggaagcgcc caggagactg
     6601 atgtgcgcgt ctttccatcc aggcagtcat caacagaaga tgtgcgggaa aaactctcct
     6661 ggtctcgagc agactgttcc tgcgccatag ggccctcccc ttcctctgca ctgtgtgtgc
     6721 agggcattgc gttgcgaccc agatcttctt gcgcagaatt catgccactt cgccggcccg
     6781 tacaaaactg gtcacggcct ataacatcag gaggttagag aacgggttct gaacagtgat
     6841 tgcgatcgcg cagggcagga tgttgagatg agccaatttg gggccatccc gcggccgtaa
     6901 tttggcaatc agctcgttgg tgtccgttgc aggcaatcta caacgttgcg agcacgccgg
     6961 actaaccagg cacatcgcta cggcgcagac catggtctcg acaacacatg ccgcggggaa
     7021 gcaggctgtt gtttgacggt tcgatgcgac atgctagaat cccgatcaag ccggtccgtt
     7081 atctccagga aaccgtgggc cgggagagac cccgcactga atcctcgccc aaccttgcga
     7141 ttcatcatga tgtgcacaac ctgccggtac aactgtgatc ggagtgtgaa cgcggcctca
     7201 tgatcaaact ccttctcgtg gaagacaatt ccgtcgatgc gcaactgacg caagacctcc
     7261 tagccgaatg gtcactggac cgtttcgaga ttacccatgc ctccgtcctg gcggatggac
     7321 tcacccgact cagccgagag cggttcgatg ttgtcctcct cgatctctcg cttccagaca
     7381 cccatggcct ggcgaccgtc acacaggtct tggcgaccag ccccgatgtg ccggtcgtcg
     7441 tcttgagcgg gcatgatgac catccgctcg cgctgcaggc gctccaacat ggcgcgcagg
     7501 attatctggt caagggggaa ggtggaactg agtttttggc acggtcaatt ctctatgcca
     7561 ttgaacgcaa gaaggcgcag gagcggctca cctactttgc ccagcatgat ccgcttacgg
     7621 ggttgatcaa tcgcgccctg tttcgcgacc ggttgattca cgccatggca cgcagcaagc
     7681 gaaaagatca gccgctggcg gtcatgctgc tggatctgga tcgcttcaaa gccgtcaacg
     7741 acacgctcgg acacgatatc ggcgatcagc tactgaaaga agtggccaca cgcttgatgg
     7801 aatgtgtgcg agaggtcgat acggtcgccc gactgggcgg cgatgaattc actgccattc
     7861 tcgaagggat ctcaggcgaa gacgatgtgc tggttgtcgc gaagcgaatc gtagactcga
     7921 ttggctcgcc atttcagatc gggccgcata atatctcgat cggcgtgagt atcggcatca
     7981 cgctctatcc ttcggacgac gaggatctcg acgagctcct gaggcacgcg gacaaggcga
     8041 tgtacgcagc caaacagcag gggggaggcc gctatcattt tcactcaccg gccggccatt
     8101 ctcccgatgt ccccgctccc ctcccgtaaa gggcccgcgt gccgccgcgc gctaggtcag
     8161 ttcaatccac ctactcttca tcgctcaccg ctaccgcccg atatcggcga gaggctgctc
     8221 cgtcaccacc accgagcccc ggggattggg caggaacacg ttccccgcca ccaattcctc
     8281 ctgcgatgga gtcggatgcg agtccggcgt catcaccaag ccccaatgct gattgtcgcg
     8341 gcagatatta tccaagagca gcgcctccgc atgatggaac aaaagcatcc cgctcagcat
     8401 gttgctatga cacacattcc gaacacactc cggatgactg cctggatctc gcaccgccaa
     8461 accaaaatgg tgattgccat aacacagatt ctgcgccacc cgaggctgcg cccccgcaaa
     8521 gacaaagatg ccggattccc gattggaaca gacctcattg tcgataaacg tcggcctcgc
     8581 ctcgggaccg tagatcacca cccccgataa gatgccttcc atggcccggc accgcgtaat
     8641 ggtgcagacc gagtctaaaa cgttcatggc ggaatgttga tcgctgccca cataccggaa
     8701 ggtaatcccg gaaatcatgc cgttgggcac tcgttgcaaa tacagtggcc ctccgcgacg
     8761 actgtatatc tgcacctggt cgcgaccagc cccgacgaga agcaccggct tatccgcaac
     8821 aaacacctta tcttcataca caccggggcg gacaaatacc tggtcatcct cgcccgcgtc
     8881 tttgagcgcc gcgctgggac aaaggtaggc atcggaatcg cgggcatcga caatcaatgt
     8941 cttcccgcct ttgggattgg gtggcggttc gatgagaggg tccttgcctg cgcccgatga
     9001 accagcctcg tgagatgtat ccatacgacc gtttcaatcc tctaggaact cgaccaagtc
     9061 attcactcca caatggagcg ctaaccacca acaaacgaca acgtgttttc tgtcaactgc
     9121 ctgccctcaa catacccttc ggctcttttc cgtacaatcc tgtgtgcttt ccgcacagag
     9181 ctttctgatc cccgagccgc tcggattaac caaccataca atttcacaac aagttcgtcg
     9241 attgcctccg gctggtgcgg ttctttcata tccacggcca caataatgga tgggttccag
     9301 acgcgccgac cacagaagaa agaggggctt ctatgaccat ggttcaactc agccgtgaaa
     9361 aggtgcgagg tatcgctgca gcattggcgt tgttcagcat cctcgcgagc gcatccgatc
     9421 tgttcgccgc gtcaccccag caaccggatg cctcacgccg cctctacgat cgcgtgatgg
     9481 acgagttccg ccacaaagac taccctgcag cgctcgccgg gtttcgcttc ttccttgagc
     9541 tccacgggca ctcatcattg tcggccaatg cgcaatattg gatgggggaa tgccagtacc
     9601 gtatgggaaa gcacgacgag gcactgggat cattcttcaa actgatttca gactatccca
     9661 tgagccagaa actcgccgcc tcgaccctta aaatcggaca gatctacacg aaacagggtg
     9721 accttgaaaa ggctcaaatg atgtacgagc gagtcaccgg cgaatatcct gatagcccgg
     9781 aggcagaagt cgcgcgtaag gccatagaag ccgctgctgc gaagggagat ccaatcgcag
     9841 ctggaccgaa ttgaccggct tgccgcattc ggtccctacg ggtcgaccaa ccgatcttcc
     9901 tcactgactc ggccggattc aatccggatc ggcgagatcc aacaccgtca cgaggccggg
     9961 aaccgtatac gtatggaatg gactgagtcg gacgagttgc acgccggcgg cgcgcagcgc
    10021 accatcgaat agagagtttg ccgtcccctg cccttctgcc tgcgaggccg agggctcgac
    10081 ctgcaccact ttctccacca accgactgcc gggatgcacc agcacaaacg tggcgcgtgt
    10141 gagcgccagc tcccgcagcg tttcggctgg aggcatcccg gagggaacgc gcaaatccaa
    10201 tacgctccag agaggaattt gagtaaataa gagatatcga tcttcgaccg caaggcgtaa
    10261 caggttgtag agctgaactt cctggtctgt cagcagaggc ttgggggcaa aggtcagtcc
    10321 ggacggcagg ctgccggatg acgcagccgg cgcacgtcgc cgcccgaatg tttcccacgc
    10381 gagacttccc aaaaggacca gcgcgccgat cgcgaggaga ggatagagta cgtccatgtt
    10441 catgcgagtc ccttaacccg gcagataccg gttcctcctc cgtatgtccg ctttgccggg
    10501 aaccacggat ccaagtaaga cgggatgacg agcccctgtc acctgcggaa cattcgtgca
    10561 gtggccgtgc aatacgtcat gtgcgagcaa cgcaaacgcg gtcgcctcaa acgccttact
    10621 actccaaccg cactcatcaa atgtcagcac cggtgcgggg gcaaacaccg tccggagcga
    10681 cgccatgata gctcgattgg agaccccgcc tcccccgacg atgacgtcat cgatcttgcc
    10741 ggggacccag cgccgcgatg aaccgatggc ttccgccgtc caggccgcac aggtcgccaa
    10801 caggtcctca atcgacagcc gcgctttctt ctgcttcgcg agcaagcgac gaaccagggg
    10861 cgcaccaaac tcttcacgac ctgtggactt cggcggacgc cgcgtcagga acggatgggc
    10921 catcagttcg gtgagcagcg gttggtgtat cgtgcccttt cgcgccaatc gccccccggc
    10981 atcgtacgta cggttgccct ttgtcgtttc ctgcataatg gcatcgagca ccatgttgcc
    11041 aggcccggtg tcgaacgcgc gcacatcagc catcacgccg cctgcaggaa gataggttac
    11101 attgctaatc ccgccgatat tgaccaccaa tcgcgtccgg cgtgcatggc tgaaggcaac
    11161 ggcatgggca tagggaacca gtggagcgcc ttcaccccca gccgccatat ctcgcggccg
    11221 gaaattggct acggtcgtga tacccgtgcg ctcggcaatc actgccggct caccgatttg
    11281 taatgtcgat cggatcaggc cgacgccgga ttcacgccgt ccttttggca agtggtggat
    11341 cgtctggcca tgtgatccaa tggcatggat atcggctggc tgatgtttcg ccgcccgaat
    11401 caccttgagc gcggcctcag caaacaattc gccgaggtac gcattcatat ggcagatctc
    11461 cgccacttgg ccatgaagcg acagatccac cactcgctgc tgcaaggcgc gaggataggg
    11521 cacggtggag aaggcgatgg gcgtgatgac cggtcggcct ccgcgccgaa cgatattcac
    11581 cagcgccgcg tctattccat ctgccgatgt cccggacatg agtccgacaa ccttcatccc
    11641 gccccccatt caacacaacc gcctgagatc gacctggcat tcgggcgcta cgctaatcga
    11701 aaccacgaga cgggtcaagc ggtacgctgc tgcagagcac tcggtttgca tgcgtcatcg
    11761 cgttgacttt gggtacatcg ggtgttacgg tccgccggat gtttcgcacg attttgctca
    11821 ctcttttcat tttcctgacc atgctgggaa acctttccgc agctgtaccc acggcatcgg
    11881 cagctgaacc gctcaacgtc gtggtgacgc tccccgtctt gaaagattgg gtgcaacaaa
    11941 tcggcgggtc tcatgtccat gtcgtctcgc tcatgaccgg atatgaaagc gagcatacct
    12001 actcgcccaa gcccagcgat ctggttgcgg tccgcaaagc tgccctcttg tttgaggtcg
    12061 gagcgggact cgaagtgtgg gtatcctcac tggtcaagaa tgcgggaaac gcctccttgc
    12121 aggtggtcac gacctctaaa gacattgaat tgatcccgga tcatcccgaa tcgactgccg
    12181 atgcccacac gcaccaccat gcgggcggta accctcacgt gtggctggat ccgtccgcgg
    12241 ccgccacgat ggtgcagcat atttccaagg ccatggtgga agccgacccg gcccacgcag
    12301 ccgaatacag aaacaacacg gctgactatc tccaagccct gctgcgtgtt caggcagaat
    12361 cgctggagcg gctcaaaaag gtgccgagcc gtgcggtcat cgtgcatcat ccggcttggc
    12421 cctattttgc ccggcgttac gatctacaga ttgctggaac gattctcact cagcctggag
    12481 gagaaccctc cgcacggcat ctgcatacgc tgatcgacgc catcaaacgc gggcatatcc
    12541 gggtcattat ttccgaggtt caactgaatc agaaagttcc acaactgctg gcccgggaaa
    12601 ccggggcgca catcgccgtc ctgaccacct tgccgggcgg tctcccgggg accgagacct
    12661 acctcgacat gctccgctat aatgtgctcc aattggccca cgcgcttgaa cagacataac
    12721 cgccgcctcc aaccggacat cgacgacaac cagcatcttc atcgaacgcg ccacgcatga
    12781 cccatccgat tatccgtttt gaccatgcga ctttcggttt tcccggcacc gtggccctgg
    12841 aagacatttc tctgtccatt cccgagtcgg aattcgtcgg cgtcatcggc ccgaacgggt
    12901 caggaaaaac cactctgtgc cgcgccgtgc tcggattgat ggcgccgatt cgcggcacgc
    12961 tccgcgtcct cgactgtgcc tgcgaggaac tgcgctgcca ccatcgcgcc ctcatcgggt
    13021 atcttccgca aaagggtatg ctggatcgca actttcccgt caccgtactg gaagcggtga
    13081 tgatggggcg atatggcgcg ctgggtctgt ttcgccggcc gtccgggaaa gatcgtgaca
    13141 ttgcccgcca ggcgctcacg caggtaggca tggatcatca ccgggattcc gcgttgggtg
    13201 ctttgtccgg cggccagcaa caacgtgtgt tcatcgcacg ggccttggca caacagccgc
    13261 gcattctgct cctggatgag ccaacgaccg ggctggacct cacggcccag cacagtgtgg
    13321 tggaactgat ccaacagctg catcaggaac tgaaactgac gattctcatg attacccacg
    13381 acatcaatat gattcgctcg cgggtggatc gattggtcct gctcaaaacg aaattattcg
    13441 cggccggtcc gccgcaggac gtgctgaagc cggagattct cagccaggtc tatggcaaag
    13501 agttggtcat tacggataaa gacttcatca tcgtggaaga ctaccatcat caccactgac
    13561 cattccgatc tcatgatgga gcctgattca cgatacaacg tgttcgttat gtcgttcccc
    13621 aatgattcac tgacctagtg agacaatgtt agagctactc gcctacgatt ttatgcaacg
    13681 ctcactgctg gccgccgccc tggtgggctc ggtctgttca gtgatcggcg tctttgtagt
    13741 attgcggggc ctggctttcg ccggtgcagg gacggcccat gccgcatttg ccggcgtcac
    13801 gctggcttat ctgctcggcc tgccgcctct cagcctcgcc attgtgttcg gtctcgccac
    13861 ggtgtggatc accggctggg tggaggaaaa ggggcgcatg aagttggatg tgtccatcgg
    13921 catcctctac accgcgacca tggccttggc tattttgttt ctgggcctca tgaagacgta
    13981 taaccccgaa gtctacgggt acctcttcgg cagtgtgctg tccgtcacca cagaggagtt
    14041 gctgaccatt ggcggattga gcatcgcggt gttggggacg attctgctgc tttcaaaaga
    14101 actctacttc atcgccttcg accaggaaat ggcggcggcg tcgggcgtgc ccgcgagaca
    14161 gattttttat ctcctcctca cactggtggc gttgaccgtc gtgattgcct taaaaacggt
    14221 cggcgcaatt ctcgtcttcg cgatgatcct catcccggcc tccaccgcct accagctcac
    14281 acacagcctc acgcaaatga cgctgtattc catgctcatc ggcattttct gtgccgtcac
    14341 cggcgtgttg ctctcctacg cattcgacct gccgtccgga ccatcgattg tgttattggc
    14401 cacaagcctc ttcttccttg ccgtctgttg ttcaccgaag cggctgcatc ggattcaagc
    14461 agaatagaca caaacgccag actgttgccg aacagcaccg ttggctggta cgtcgtgcca
    14521 gtgtgccaat aagtagaagg gacgggagcg aaggacaggg ggtctgttag gactgagtgg
    14581 atggttgctt tcgagaccag accatgccgg tctgctcctt tgcgctgaaa ccgagccgtt
    14641 cgtagaatcc cggcatgcgc gtgcacaacc agaacaattc aacctgctgc agcgtgggat
    14701 ggtcgagaat gcgccgtacg atttcagtgc cgatctgttg cccctgatag tcgcgatcga
    14761 caatcacatc ccagattgaa gcgcgaaaga tatagtccgt caggactcga ccgaatccta
    14821 ccagacgtgg gccgtcccac gctgaaatga cgagatcggt cttcgccagc atagcttgcg
    14881 cctgctctaa cgcgcgatgc ttggcccagg gagcctgccg gtacaaatgg atcagttggg
    14941 tcgcgtcgaa atcgttgcga tcggaaaatg cgatgggtcg ttggccggtc ttgagagcag
    15001 gaggcatctt gtactaaatt aatccctccg aacgggagta atcggttaac cgtagtgtaa
    15061 gaggaagcct atgggaacgc aagtaagaag ctgtccgaag tgttttcaat tgatgtggct
    15121 caagcaggac cactacgacg tgatcgacga ggaaacggtc cgcacgaaat gtccacactg
    15181 cgactcgacc gtccgctttc agttggtcac cgccggcgcc aacgctgcgg gaccgaaaat
    15241 gggacactaa ccgctcggcc agtcctgctc tctgagtgct gaattccaca ttggcgattc
    15301 atttcagagg tcatcaatga gccctgctga ttgcagggct acatgccccg tccggcgccc
    15361 tccaactccg gctgattgcc cggcagaatc ttgatcagcg ccgcacggta ctcgcccatc
    15421 cgcttgtcct ccgccgggct gaccttaatt tccttatccc gctgcatccg ctccacctga
    15481 tcaagcaccg ccatcagcgg ctgcaccgag cccagcacat tgccgacttc gaacgcttcc
    15541 aacgattcaa gcagatactc ctgcaatccc ttgaatggcg atcggccact ctgctctcga
    15601 aaacgcaaga gcgcctgctc aaatgcttcc acggcctccg gtttgggttt cacgccggtc
    15661 ggcacggatg cgagatgcac gaccgtcggt aacttggcgg catatccctt gagctgcgca
    15721 atcagctctc cgatccgatc gagcacggca ctggtttcca tcgttcgctt ctcctcaccc
    15781 tcgccgactt gaacggtcgg cctcctgttt tgttgactgc acatcactgc cggcaggcct
    15841 cccctgtgtc aaggcgtcgc gaaggagatg ctgcacctgc tccatatccg ggggaaacgg
    15901 cacatcgaac tcatgatact ccccgcccgt gggatgtgtg aatcccagcg tgcgggcatg
    15961 cagcatgacc cggggtatcg ggatgcccgc caccgtcatg acttttgctc ccccatatgt
    16021 tttatcgccc agtatgggat gatcgatcga ggtgaggtgg acccgcagct gatgggtgcg
    16081 ccctgtcctg ggggaaagcc gcacctgtgc ggcaatcttt ccatatcgct cttccacctg
    16141 gtagtccgtg gcggaggctt tggggttagt ggtgcgggcc gaaaacttct ttcgctcttt
    16201 cgtatcgcgc ccgatagcca gctcgatgag gccgtgccct ttcttcggca ctccccaaat
    16261 caacgcttca taaacgcggg tgatcgtgtg caatttgaat tgcgccgcca gcgcacggtg
    16321 cgcttgatcg gtcttggcaa tgaccatgac cccggacgtt tccttatcga gccggtgaac
    16381 aaggcccggc cgctcttttc cgccgatgtg agagggagtg acgcccgcgg tggcaaagtg
    16441 atgcaataag gcgttcacca tcgttcccga ccaattcccc ggtgccggat gcacgacaag
    16501 gcccgcctgt ttattcagga ccaagaggtc ggagtcttcg tgaagaattt ccagagggat
    16561 cgcctcaggc tgcagatcaa gaggctccgg gcgcggcact tccagtctga ttcgatcacc
    16621 cggccggatc ttttgactcg gccggactgg ttggccattg atttgaatgc ggccctcccc
    16681 aatcagccgc tgcaaggccg agcgggaaaa ggtcgggtca cgattggcaa gaaagacgtc
    16741 gatccgtttt gacgattctc ccccggtgac aacaatctcc accggcgtcg tgctgactct
    16801 attcacgtgg taactgccaa atctgtgacc gacatcatga gcgggggtaa gctgccatag
    16861 ggaggggcta aaaacaagat gtcgagatat ccaccttgct tcacaagtcg cacacacccc
    16921 atccacaagc catccacaag tttgtgctat tcgatcctcg gcacgtcccg gcagcggcct
    16981 atcgtcaggc cgttcatctt tgtcaggggg acggcaaatg tgacggggcc atgacgcgta
    17041 atttatgact cccggtgctt gcgcgaaaca gactccgaca caaatcagtc ggttggcgtg
    17101 cggaatattt tctcgttttg aggcacttga attgctttct tataagaagg atttcgcgtc
    17161 gcacctttta gcgagaagga ccatctgatg tcctcaaatt ttatccacag aatcctcaga
    17221 tcgctacgca gttcggttga tcccaccccg tcagtcgaac cgctggttgt ggacaacatc
    17281 acagacctgc cactgactga ggtcctccgg gaacggcggc tcgatgctcg attcgcggtg
    17341 agaacgccct gcctttacga attggacagg aagcagcggc gtgaaactcc cgtgatttcg
    17401 ggcaaggctc actcattgaa tgtcagttcc ggcggcgttc ttttgttgct cgatcaacaa
    17461 ccacaaaccg ggcaggtcct gagccttcat aatccgacgt tgcactcaca accgggaacc
    17521 agtctgttcg aggtccgatg gacgacgtca cttccactcg gcgcgcagca aggatgttat
    17581 ctggtgggat gccatttggc ctttggacgt tttccgtttt tcctcgtcca acggcaatat
    17641 ctgcatcgcg atatttccag cctctccatc tagtgttcga attcacacac actcatcaca
    17701 cacgccggag gatgaggcta ttcactgtgt tcgtcctcgc ccttccctca cggtcttgaa
    17761 acgtagttcg tcactcagtc cgcgaaaatc ggccggtggc ttcaccgtaa attcgcaata
    17821 acgccctgtc agaggatgat ggaaacccag cttgtacgcg tggagcatta cacgcggcac
    17881 cccatatcct tccagcgcac ggacaggttc tgcaccgtag gccggatctc ccaggatagg
    17941 gtgaccaatc gcgtgaagat gggctcgtat ctggtgggtg cggccggtcc gcggggtaag
    18001 caccatatgc gcggccgcag caccgaacac ctcctcgacg taatactcag tgagtgaggc
    18061 ctttggatgc agcgtgtggg gagaggttcg tttcacgttg ttacgatcgg ttccgagcgc
    18121 aagctcgatg cggccatggg agtgctgagg gacgccttgc accagggctt cgtattgtct
    18181 cgtgatcgag tgctgttcaa actgcaccgc aagccgtcca tgcgcggtct ttgttttcgc
    18241 cacgaccatg acgccagagg tgtctctgtc taaccgatgg acgagtcctg acataccgac
    18301 gactcccgcc cgcaaggcat gatcgagaag cgcattcaat agggtgtcat cccaatgacc
    18361 ggggcctgga tgggctgcga ctcctgcggg tttgtttatg acgaggcagg cggaatcttc
    18421 gaacagaatc tctagtgctg acggctgccc attgatcagt aagggggtcg gcttgggttt
    18481 gtcgaggttg accacatcgc ccggctttat tttctgactg ggcttagccg tctgattgtt
    18541 cacgcgcacc cgtccggctg aaatcatccg ctgcaccgcc gcacgagaga gtttcggctc
    18601 acggttgacc agaaagatat ccagccgttt cggttgttcg cccggcgaaa tgagaaattc
    18661 tgtctgcatc gcccgctagg ctacggcagc atggcggacg attgcaattg gccagaacac
    18721 cgagcagtaa tcgctctgaa ggtttggggg ttcgccgaga aacccttagc ggacagagaa
    18781 tagcctgaca acgtgaatgg cagtagtatc gacacgaaac tcgatcaggg tctggctccg
    18841 gacttgagta attgggcctt gagacgatcg atttccaggt ctttctccgc cagttcctgc
    18901 ttcagccgtt cgatttctcc ctgaatctga ggcagcatgg gctggtcgtg agggccgccc
    18961 tggactgatg catcagcggg agacgtgagc gcctccgctg agctctgctg tctgattggt
    19021 gacggagcgc tggtgggcat ctcgcgtggt gccgcgtgcg tgacatagga gaggaatgct
    19081 gaatggtcga ggacaagttc gctggctgaa gcccggtgac caccagacca gttggcttta
    19141 gtggagagtc taaacctcga cggttcgaat gcgagtactc cgccgctccc ttgaatggag
    19201 taaaacgggt tagctcgcac tcgtaccaat tcatccgaat tgtttccgac catcgttcgg
    19261 tggttggcca ccacgacatg caacctatga gattcgagaa agagaccgcc tgatgttact
    19321 ccggttgcgc cggcgttcgg ctccaagaga aggaatgcga tccactcccc tgggcgcgcc
    19381 ttcccaaagg cttctcgaac agccggctcg acgaggtcaa tttctaccgg cgtaaatact
    19441 ggctttgcgg gttttgcatt atccattaag cccacacgct cttcgagaaa gagcctggat
    19501 aggatggcgg agagctcttc ggccttccat gaaaatggat gatcatagac tactggagat
    19561 ggttcagtgg actgaaccga atcgaggcga acaaaccagt cggaccgctg ttgcacgtct
    19621 cgactcagca gcacagggcc ggcacagccg gagcatatca ataggaaaag gaagaaccag
    19681 gcatagcgag agagtctact aggcagtact tgaggaccta gacgagctcg ataaggaaga
    19741 acggcagata cggaacgaga agaagttcca ggcgagaact taagcgtgtc ctgtttttcg
    19801 cgcacggtcg gcgatctttt tgcgaaggcg agctttttcg aggctgattt ccgcttccct
    19861 cacttctgac gggagaccgc cggcctgtaa gcgttgctcg gctttttcga cagcctgttg
    19921 cgcacggccg acatcgatat cttcggcctt ttcggcaatt tccgccatca cggtgacctt
    19981 caccggcgtc acttcggcat acccccagag gatcgacatg tagtgccaca cctcttgaga
    20041 tttatatcga agctctccaa tacggaggct cgacagcaga tgacaatggc caggcaagac
    20101 accaaattcc ccctcactgc ctggggcgat gacctcatca acctcctggc tcaggagcaa
    20161 cttttccggc gtcacaactt ctaggagaat ctttccagcc attgtccttt tcctgctctc
    20221 tcgcaaaagg ctaacaccag gatgccctgt cgtccgcgca tcggccgggc accttctgaa
    20281 tgtgcgcggc ctgcaagccc aagggcacct ggctgctaga ctttcactcc catcttttca
    20341 gccttcgcga ccgcttcttc aattggaccg accatgtaga aggcctgttc gggaaggtga
    20401 tcgtatttcc cttccaggat ctccttgaag ctccggaccg tgtccttcag cttcacatat
    20461 ttcccgggtg cgcccgtgaa ggcttcggcc acatggaacg gctgcgacag gaaccgctga
    20521 atctttcgcg cacgcgccac gaccatcttg tcgtcttcgg acagttcgtc cattccgaga
    20581 atggcaataa tgtcctgcaa atccttatac cgctgcaaca cggactgcac accacgcgcc
    20641 accttgtaat gctcttcgcc gatcacttgt ggatccaaaa tacgtgatgt cgaatcgagc
    20701 gggtcgaccg cagggtaaat gcccaactcg gccagctgcc tggacaacac cgtggtggcg
    20761 tccaagtgcg cgaaggccgt ggctggcgcc gggtcggtca agtcgtcggc cgggacgtaa
    20821 atggcttgca ccgacgtgat ggaccctttt ttcgtcgagg taatacgctc ttgaagggcg
    20881 cccatttcag tggacaggtt cggttgataa cccaccgctg acggcatacg acccagcaac
    20941 gcggacacct cagaaccggc ttgggtaaac cggaagatgt tatccacgaa caacaacacg
    21001 tcctgatttt cttcgtcacg gaaaaattcg gctacggcca gtccggtcaa cgccacacgg
    21061 agacgcgctc ccggcggttc attcatctgt ccgtacacca aggccgcttt cgacttggtg
    21121 tggtcatcgg gatcgatgac cttggattct tgcatttcgt gccaaaggtc gttgccttct
    21181 cgagtacgct caccgacgcc ggcaaacacc gagaatccac cgtggtggag cgcgatgttg
    21241 ttgatgagct ccatgatgat gacggtcttg ccgactccgg caccgccgaa gaggccgact
    21301 tttccgccct tgctgtaggg ctctaacaag tcgaccacct tgatgccggt ctccagcact
    21361 tcggttttcg tgtcctgatc ttccaatctc ggagcgggac gatggatcgg gtacgtcttg
    21421 ttggtcttga tcggaccctt ttcgtctacc ggttcgccga gcacgttgat cagccgaccc
    21481 aacgtttcgc ggcctacggg aactgcgatc ggggcaccgg tgtcggtcac gtccatcccg
    21541 cgcgtgagac catcggtggt cgacatcgcg atgccgcgca cacgattttc tccgaggtga
    21601 gaggcgactt ccagagtgat ccgcacggca ggctttccgg ccgccttatt ctcttcttgc
    21661 gtcaccttca gcgcgttgta gatattcggc agttgaccgg gaggaaactc cacgtcgacc
    21721 acggggccga tgacttgaat gacttttcct gtgctcataa cgctcctctt gtcgtcactg
    21781 atgcacccgg cagcttaccg tcgtgcagca ttcctcagtc cagatttatt tcagggcctc
    21841 tgctccaccc acgatgtcca tgagttcttt ggtgatggcc gcttggcgag tcttgttgta
    21901 atacaaggtc actttcttga tcagttgtcc ggcattacgg gtggcgccgt ccatggccgc
    21961 catacgtgcg ccatgttctg cagccgccga ttccaataaa atgcggtacg tctgaatttg
    22021 aaagtgcttg ggcaccaatg cgctcagaag ctcgccctca tcaggctcgt acagatagct
    22081 gcctccaagg gacgaaccct cggtggcttg cgacgcaccg aactccgtag cggcgtcgat
    22141 agggaacagt ttttcgacaa tcacgcgctg ttgaatcgca gacttgaact cgttgtacac
    22201 cacgtagagt tcgtcgaatg tccctttgac gaaattttcg gtgagatcgc cgccaatatc
    22261 gatggcgtgc tcaaaactca gcttatcgaa aatgcccgtc cactcttggc gaatcggcaa
    22321 ggaacgacgg cgaaaataat ctcgcccctt gcgtccgatc aggctgagat tgaccgagag
    22381 tccttgagat tcacactgcc gcacgaattc ggcgctcttt cggacgatgt tgccgttgaa
    22441 tccgccacag aggccgcgat cgctcgtgac gacgaggatt tcgattttct ttccctcacg
    22501 cttttgaagc aagggatggg aggtacgatt gacgcgctgg ctcaaattgc tcagcacgcc
    22561 gcgcattttg tgcgcgtacg gccgggcagc gagaatacga tcctgcgagc gcttgagctt
    22621 tgccgccgcg accattttca tggccttcgt gatcttctgc gtatttttga aggcggcaat
    22681 tttccgcctg agtgattgta agctcggcat attttacgga agcagacagg tgcgattgga
    22741 cgagtcagtg aagagaggac tggtcactcc ccgatcacgc aatcacgata tcttactttc
    22801 ctccatagcc cattttctgc ttaaaggtcg tgatgatttc tttgagtttg ccacccacct
    22861 tgtcgtcgat cttcccgaca gtggcaatgt cttttcgcat atcctggtga ttctgcgcga
    22921 catagtggag cagatcggcc tcaaactgga gcaccttgtc caccggcaca tcgtcaagga
    22981 atccgttgac acccgcataa atcgacaaga cctggtcggc aaccggcatc ggcttgtatt
    23041 gcccttgctt gagcagttcg accatgcgga caccgcgggc caactgcatt tgcgtggctt
    23101 tatcgagttc actgccgaac tgggaaaagg ccgccatttc gcgatactgg gcgagatcga
    23161 gtcggagcgt accggcgacc tgcttcatgg tcttgatctg cgcggaaccg ccgacgcggg
    23221 acacggacag accgacgtta atggctggac gaataccgga atagaacagg tcgctaccaa
    23281 ggtaaatctg gccgtcggtg atcgagatga cgttcgtcgg aatataggcc gacacgtcgc
    23341 ctgcctgcgt ctcgatgatc gggagcgcgg tcaaactgcc gccacccaac ttgtcgctca
    23401 atttcgcggc gcgctccaat agacgggagt gcagatagaa cacatcgccg ggataggcct
    23461 cacgaccggg gggacgacgg agcaagagcg acagctgtcg ataggcgacg gcgtgtttgg
    23521 acaaatcgtc gtagacgatc agcgcgtgct tcccgttgtc acggaaatac tcaccgattg
    23581 cggcacccgc aaacggggcc aggaactgca tcggcgccgg gtcgctggcc gttgccgcca
    23641 ccaccatgct gtactccatg gcgtggtttt cttcgagcgt cttcaccact cgcgcgacgg
    23701 tcgaccgttt ctgtccgacg gcgacataaa tgcagaacac gccgagaccc ttctgattga
    23761 tgatggtgtc gacggcgatc gcagtttttc cggtctgacg gtctccgatg atcaactcac
    23821 gctgaccacg accgatgggg atcatggcat cgatggcctt gatgcccgtc tgcaatggtt
    23881 cgcgcacgga ctgtctggta ttgacgccag gcgccactac ttcgatacgg gaggaatgtt
    23941 gcgaattgat gggccccttg ccgtcgatcg gctgtccgat ggcattgacc acgcgtccga
    24001 ctagggcttc gcccaccggg atttcggcaa ttcggccggt ccgcttgacg ggatcgcctt
    24061 ctttgatacc agtgtcatcg cccatcaaca cggcgccgac attgtcttct tcaaggttca
    24121 acgcgatccc gtagaggccg cccgggaatt cgagcatctc tccggccatc gcaccatcga
    24181 gaccgtagac tttcgcgata ccgtcgccga cctggatcac ggacccggtc tggctgacat
    24241 cgacctgttg atcgaagccc ttgatcttct ctttaataat ggagctgatc tcttctgcct
    24301 tgatctgcat ggctactcct tggtcaacac tcgctgcatg gcgctcagtc ggccccggac
    24361 cgtgctgtct acgacggtgc tgcccaggcg gatgtggagg ccggcgacat gttcaggttc
    24421 tgtatggaaa gtgacatcga catcgcgctt cagcagatcg cgcaatcggg tggtaatgcg
    24481 atcctgctca gtcgccggca acgcattcgc ggatgacacg agcacttgct gcgtgccttt
    24541 ggattcatcc accagcttgg caaaggcatc ggcgatgtcg ggcaggaaac tgacacgatt
    24601 ctttttgacg agttgatcta ggaaccgctt gacgaccggc gggcatccga gcttagtggc
    24661 gacttcgatc agcacactta acttagtggc ttcagggaac attggagaag ccacggcatg
    24721 ccgcaatgcg gatgactcgg taaaggcttc tcctagtcca ttgagggcca agcgggccgg
    24781 ctcaatgctc gaggcatcaa gaagttcgaa cagagctttt gcgtatcgac gtgcgacggc
    24841 tgtcttaatc acaataacta tccgctacgg ttaaccgtgt tttgatcaaa cgggaagctt
    24901 gcgtgcggtg ggcacgacaa aaagcgcgcc aagttagcat tcaaacgcgg gtactgtcaa
    24961 ggaggatccc atggctggca ggaggaatgg tcgcaggagg accgtcaaag cggttcggaa
    25021 aagaccgagg caaaaggcat cccaggcaaa tattgattgt gtttttacgt gctgaaaagc
    25081 gaacaacggc aggccacgcc ttacgtgcgc tgaatgatgc cgccgccaag cacacgatct
    25141 ccttggtaga agaccgcgga ctgtccgggg ctcagcgctc gttgcggctg atgaaaccga
    25201 atctgcacgg tcccgttggt tgatggcaac agcgtcgcgg cggccggcgg agtggcatac
    25261 cggattttca catccacatc gacggcctgt cgaccgatgc tcctatcgaa caaactgata
    25321 tccccgacct gacaatcgga ctgcacgagc tgttcttccg cgcacaacac tacttcgcct
    25381 gactcgggga cgactttctg cacgtacaat ctctgcccaa ccgcaatgcc aagtccgcgc
    25441 cgctggcccg gcgtgtaaaa agcgatccct tcgtgtcgcc ccaacacttc accatcgaca
    25501 cccacaaaag ctcccggctg cttgagttcc ggccgttcct gctcgaggaa ggtccgatag
    25561 tcgccttggc tcacaaaaca aatctcctgg ctctccttca gctcctcgac gggcaatccg
    25621 agggtttccg cctctttcca cacgtcgctt ttttgcatct ctccgacggg aaacaagagg
    25681 cgcggcagcc agtcggcctg gatccgatac aaaaaataac tctggtcctt gcgcgcatcg
    25741 agtgcccgat gcaacgacca ttgtccgccc gcctgctgga cacgcgcgta gtgccccgtc
    25801 gccacgtagt ccataccccg ctcctgcgcc agggcataga gagaacgaag cttgacccgc
    25861 tcattgcacc ggacgcaggg attgggggtg gttcctgcgg catatccggc aacaaagtca
    25921 tcgatgacac cctgctgaaa aatttcccgg cgatcgacga cctcaaaagg aatacgtagg
    25981 cgttgcgcga cgaacttggc aatcccgatc ttgcagcagc cccgctcctc ccatcgctta
    26041 gacaccgcga catgctcgtc ttcgtgctcc cagacctgga gcgtgacgcc atggacatca
    26101 tacccttgct ggacgagcaa cgatgcagcg acggagctat cgactccgcc gctcatccct
    26161 agcagcaccg tctgacgtgt cataaaaaat accgggggaa caaggagccg cgcacttacg
    26221 gctcttgggt tttgacttta ccgcgatggg ccacaaggtc acgcacgccc ggatcctgcg
    26281 gagaaccgaa ttcggaagcc tcgtcctccg accacttctc agcgcccatg ttgctcatgc
    26341 cgtgaaaatg ggcaccttct tcgatcataa tgacggggct ttggatgtcc ccgatgagaa
    26401 tcccgggctt ctgaatttcc accttctgct gcgcagtaat cgatcccttc acacgcccgc
    26461 tgatttcaac ggatccggcg gcaatcacgc ccttaatcac ggcgctttcc ccgacgatca
    26521 ccgcaccacc tgtgtggact tcgccttcga cgcggccatc gatacggacg gtgccgtcaa
    26581 aggtgacgat gcccttaaaa cttgttccct tcccgagaaa ggtaaacttg tcggattccg
    26641 cgacggactg ctttttggtc tcaccccaca tcagcgtcct ccttcacgca ccccacgacg
    26701 gtgaccgccc gtggcgcgga ctgaatggaa ctctattgat gccgatccgg cataaggccg
    26761 gtcgcacgct gtcctatgat tcgtgatcga gccggactaa ccgttgacga gctttacgcc
    26821 ctgtccgcgt gacgtacctt gcggttcgcg ggtccccgtc tggctcatct ccaacgtacc
    26881 attgaacacc acgccctctt ccatggcgag caacggagcc tttacacccg cgttcaccac
    26941 ggcaggcgcg cgcaacttca ctttctcacg cgcactgatg tcgccggtga tctttccctt
    27001 acacaccacc gtgccggccg tgatcttcgc ggtcagcacc gcgtcctcac cgaccaacag
    27061 aacaccttcg gtgtgaattt cgccatccag attgccatcg atacgcacgg tgccgttgta
    27121 ggaaatgacg cccttaaagc tgacaccctt cccgacaaag gcattgatct cttcattccc
    27181 ttcacggggt gctgtcgatt ccaaattttc catttcactt ccctcgcttt gtcctgcctg
    27241 gcgctttcct tctggtttgt ccttaatcca catagtgcat acctccaaac aaataaccac
    27301 acgtctgacc ggcggagcgg gaattcttca ccgtccactt cgatgacgag acaaattccg
    27361 tcggcattgt actccggtca aaccgtaaaa tctgccctga aaatgcctcc gctatccgtt
    27421 cagcaactgc tcaaccacgc cgtccagttc ttcaggagaa aaataatgaa tgatgatctt
    27481 tccgccacgg cgccccttct gaacatcgac tctggtgccg agccgtttct gcaaccgctc
    27541 ctcgagatct gatcgcaacg gcgcccgcac cggacgcttc cctgcttttt tagcctctgc
    27601 gtgcccttga accaatcgct ccgcttctcg caccgacaac tgcccgctca cgatctgggt
    27661 cgccaaacta atttgcgcag ccggggtcat cagaccgagg atgaccttcg catggcctgt
    27721 cgacaactga tctgtttcga tcatatgctg aacttcggcg ggcaacgagg tcaggcgcag
    27781 catgttcgcc actgatgacc gatcgcaggc gaccttttgc gcaatcgcct cctgcgtgag
    27841 gctgaattca ttcaacatgc gctgatacgc ccgggcggtc tccatcggat taaggtcatc
    27901 acgctgaagg ttttccacca gcgcgagcac catcgattcc tggtccgaca catttcggat
    27961 aagagcagga atcttctgca ttcccgccaa cttagcagct ctcagccgcc gctctcccgc
    28021 gatcaattca tagatgccgt cgccctttcg gcgaactaaa atgggctgca ggaggccatt
    28081 ttgcttgagc gacgctgtca gttcagccag ctcgacctcg gagaactgct gccttggctg
    28141 aaaacgattc gggacaaccg cttccaagcg caactcctga acatcgcctc gctcgggatc
    28201 ggccgtattt cggccagtcg gcaacagagc gtcgagacct ctaccgaggg cttttttctc
    28261 catggaccac aaactccttg gctagggaaa gataggcttg agcaccggat gatgccatgt
    28321 tgtagagcaa cgccggacga ccgtaactgg gggcctccgc cagcgtgacg ttacgcggaa
    28381 tcatggtttg atacaccgct tcgccaaagt ggccgcgaat ctgctcgacg acttggcgcg
    28441 ccaaagaatt acgtgcgtca tacatcgtca gcacaatgcc ctcaatttct aagctcggat
    28501 ttaatgactg tctcatgcgc tcaatgcttt ccatgagtcg cccaagacct tccatcgcgt
    28561 aatattcgca ttgcaccgga atcagaacgg agtgcgcagc gaccatggca ttgatggtaa
    28621 gaagaccaag ggccggtggg cagtccaaca aaatggtgtc gtatcgatca gccacctcgg
    28681 ctaaggcctc cttgaggcgc tgctccctac cttccatatt cacgagttcg acctcagcgc
    28741 ccgctagatg tgaatttgca ggcactaacg acaagccgtt aaccgcagtg ggcatcgcca
    28801 gatcggtaat actttctttc acaatcaagg cattgtagat ggtctttcca agcgacatgg
    28861 cgtcgacacc gaggccactg gtggcattac cctgaggatc aatatccacg aggagcacgg
    28921 atcccccctc aattgccaag gccgcggcca aattcaccga ggtggtggtt ttgcccactc
    28981 cacccttctg atttgcgaca gcaataattc tcgccatgtc atccccaatc ttctagcagc
    29041 acactgaacc gactgcgatg ttccacgtgg aacatccgag ctggccttct atttcgagaa
    29101 tacggaaaga acgcgatgtc catatccgga tggaagctca tactcgactt cctgcaccaa
    29161 agcaaggcca cccagtctaa aacctctcgg aacccgctcg gctcgatata aaatcacttt
    29221 tccggctggt ttgaggagat cggccaccat ctggccactc tcgtctacct tgaaagctcg
    29281 cactacgatg taatcgaaca gtcgccgagt cggtcggcga acgtactgct ccaacttgga
    29341 tgggacaaca gtgacatgcc tcaacccgag ggacccggcg acatacctca gaaaggcccc
    29401 cttcttctcg ctcggctcaa gcagttctaa ctctatttgg ggcagcacaa atttaagcgg
    29461 cagacctgga aatccagccc cagccccaat atctagaagc tcacatttgt ccatattttc
    29521 aatgactttt accccagcca cagaatcgat gaaatgcttc accaggactt cctgatcatc
    29581 atggatggca gtcagattga tcgccttatt ccattttttg agctctgaga ggtaggtaga
    29641 aaaaaacggc agacaagaac tatctacagg gatgccgagc tctgcggcga atcttcggaa
    29701 agatacttca aactggctgg cgtcgtgttc cacgtggaac aattacgcga aaccaatacc
    29761 aagggtcaag aatgtttctg caaattagga aggctggcca gaaagagagc ggaataccga
    29821 aatcattcag cagtgagggg ctgacgcttg tggcgctcga tcgcaaccaa taacagcgaa
    29881 attgcggcag gcgtgactcc ggaaattcgt gatgcctgcc caacagatgc gggccttaca
    29941 cgtttgaact tttcccttac ctcggcagaa aatccagaca catcgtcata gtcaaagctc
    30001 tctgggatcg ccctgtgctc gaacttttgt gatcgctgga tttgctgctg ctggcgctta
    30061 atatagccct cgtactttac ctctagctga accgcatcca taatatcagc atcttcaatc
    30121 tcgcacccgc cgaacaccga agaaatcttc ccataggtca gatcctgccg cctgagaatc
    30181 tcggccaacg attgcgtcgg cgtcaccggc ccaatctcga attcttcaag cagcctcctg
    30241 acgtccggcg ttaacttcgg cctcgtatcc ttcagtcgct gcacttcgcg ctcgatggcc
    30301 aaacgcttct cttgaaattt atgatggacg ctatctggga tgagcccgat ccggtgcccg
    30361 agatccatca ggcgaagatc cgcattgtcg tgccgcagca gcaagcggta ttccgcgcgt
    30421 gaggtgaaca tccggtaggg ttctctcgcg tctttcgtga tcaaatcatc aatcaataca
    30481 ccgatgtagg cttgagatcg gtcgagtacg agtggcgcat ctcctctcaa cttcaacgcg
    30541 gcattaatac cagccatgat gccttgagcg ccggcctctt cgtagcctga ggtgccattg
    30601 atctgaccgg catggtaaag cccctgcaca agcttcgtct ccaatgaatt atggagctgc
    30661 cgcggcggga aataatcata ctccaccgca tacccaggct ttaagatttt ggcctgcttc
    30721 aagccgggaa tagttcgtaa gatggctgct tgcacatcca ccggcaaact cgtcgaaatg
    30781 ccattcgggt agaactcatt cgtatcgagc ccctcgggct caatgaaaat ctggtgccgg
    30841 tccttgtcgg caaatctcac gaccttatcc tcgatcgacg ggcaatagcg tggaccgata
    30901 ccatcgatga cgccgctgaa caatggcgac ctgtctatat ttttagcaat aatatcatgt
    30961 gtttgcgtgt tcgtatgggt caaatgacac ggcacctgcg gaaggggaat tcgattcgtg
    31021 cggtaagaaa agggcggcgg cggatcgtca ccgggctgaa gttccatgac cgaaaagtcg
    31081 atggtatcgc gatccaaccg aggcggagtg cccgttttca gacggcccac ctcaaacccg
    31141 aaatcgcgca tacaatctga aagatgttca gctgaagcct ctccggctcg tcccgccgga
    31201 aaatgactca gaccgatgtg aatgagacct ttcaaaaagg tgcccgaggt gagcaccacc
    31261 gcccgagcct caatgtgctg acctgaatcg gtcacaatgc cgaccacggc cccggcatgt
    31321 gtcaggatac gatcgaccgt tccgcctctg atgcgaaggc acggctgtgc gcgaagcgta
    31381 tcctgcatca cttggcggta aatcttttta tcgcactgcg cgcgcaacgc gcgaaccgcc
    31441 ggccccttac tcgtgttgat catacggaat tggatgcctg cctgatccgt gttccggccc
    31501 atttcgccgc ccaaggcatc aatctctttg acgagatgcc ccttggcgat tccaccgacc
    31561 gccggattac aagacatttg ggcgatacgg tcaggatcca tggtcagcaa cagagtgcgc
    31621 gcgcccatac gagccgcagc caaggccgcc tcacagccgg cgtgtcctcc tcctaccacg
    31681 atgacgtcac attgctcgct catgcccgac accctttcat ttcccgatac aaaactctgc
    31741 aaatacgcga tcgaggattt cgtcggtcgt aatgacgccc gtaatttctc ctagggcatc
    31801 tgcggcaatg cggagatcca tggcgatcaa ttcccctgca cggccagcct cgacggactg
    31861 cctggcctga tcaacccctt gcaaagcccg ctcaatggcg acagtgtggc gaagattggt
    31921 caccagcaca ccttcattcg actcccacat ccccggcatc agccgcccac gaatcgtttc
    31981 gcgcagttcg tccagcccga tcgacaacgt cgcggaaatt tcgagaatac cgctatggcc
    32041 aggacacgcg cgatcaagat cctccctcga caattggcca gggagatcgc atttattgat
    32101 gatgagcaac gcacgcgtcg aatcaggctc tgaaaggagc gcccgatcgc tctcggacaa
    32161 ggactgggaa ccatccagga ggataagtgc gagatcggca tctgtccaag ccagcctgct
    32221 ccggcgaatc ccttcgactt ctacgggatc gtccgtcacg cgtatgcccg ccgtatccaa
    32281 caatcgcacg ggaatgccat caatgctgag cgattcctcc aagagatctc gggtcgtacc
    32341 ggggatagcc gtgacgatgg cgcgatcact tcgcaataag gcgttcatca aactggactt
    32401 cccgacattg ggacgtccaa gaatcgccac gactgcgcct tccctccaaa tgcgaccatc
    32461 acgtcccgac tgaagcaacc gccgcagctt ctgcagggtc acatcaagca ggcgcaacaa
    32521 ttcgtcctga cgaacaaacg aaatatcctc ctcggcaaaa tccaaagcgg cttcgatgtg
    32581 tgccagagcc acaactaatt cagatcggat ctcctccacg tgccgggata actcgccccg
    32641 gcgctgcgac tgggcgaggg tgaggctgcg tgcggtcttc gcgcgaatgg tatcgagcac
    32701 cgcctctgcc tgcgccagat cgagacgccc attgagaaac gcgcgcttgg taaattcacc
    32761 cggtgcggca agcctggctc ccgctgagat taatccccga cagagctgat ccagaatgac
    32821 gggaccaccg tggcattgca cttcgactac atcttccccg gtgaaggaat ggggcccttt
    32881 catcacgacg acgagcgctt catcaataaa acgcaacgcc cccgtgcgct tggtaccagc
    32941 ggcaggtacg tccgtattgt cagcgcagat gtcggcgagg gcgagccgat gcgtgggaag
    33001 atcttgcaag gcgttacccg accggagacg tacaacgtga gacgcgacgt caagggcgtg
    33061 aaagccactg atgcggagta tgccgatgcc gccctccccg ggaggggtgg caatcgcaca
    33121 gatggtatcg tctagcgcgc caagcatgac gcacccagtg aggtggtgtt attcagtcgc
    33181 ggaggcgttt cgccgtttac cgttactttt ctgttctttc gaatcttcga tggcagcggc
    33241 gtcagcgccc tcgggcacca cctgccactt cttcccaaat aaccgctccg tcacgacctg
    33301 ctgcgtaatc gtgagcgtgt tgttcgtcag ccaatacagc accaatcctg ccgggaagtt
    33361 gacgaacagg aacgtcatga acactgggag gaacaacatg atctttgctt gcgtcgggtc
    33421 catggtggtc ggtgtaatct tttgctgaat gaccatggtg gcgcccatga tgatgggcaa
    33481 aacgtaatag ggatcctgca cggaaagatc tttgatccag agcatgaacg gcgcctgcct
    33541 gaggtcgatc gtcatgtaga gaatattaaa cagcgcgacg aagaccggca tttgcaggac
    33601 catcggcaga cagcccccga cggggttcac ccgatgatcc ttgtagagct tgatcaactc
    33661 cttgttcagc cgctcgcgat catccttgaa cttattttga atggccagaa ccttcggctg
    33721 aatgacctgc atctgcttca tcgacttgta gcttttgtac tgcagcggca cgaacatcag
    33781 cttgatcagc atcgtcaaga gaatgatcgt gacaccatag ttgtgcgtaa actcgtagag
    33841 aaagcgcagg acataaaaga tgggcttggc gactgctttc accagtgccc aactgccaaa
    33901 gacaaaccaa ccaaagtcga tcgtatcttc caagccgaca tttaagccct tcagggtgtc
    33961 gtactctttc ggtccggcat acagctgcat cgtcattgtc gatccgggag tcggcgcagg
    34021 aaacctgact ccggcggaca ccagcttatc gccctctttc ttcgccagcg cagacatcgc
    34081 cttcttgggc atcaggacgc tcaggaaata cttgtcctga atggcggacc acttcacatc
    34141 tcccttacgc tccgcttcac cgtccggggt ttccttcaag accttgtcat caaccaggga
    34201 ggctgagccc atcaggccaa taaatccttc gccccattcg acgatgccaa aattggtccc
    34261 gagagtgaca tccacgggcg tggccaggcc ttgcgtccga accgcgatat ccaccacgta
    34321 cgatccgtga tggaacgtca actccttctc aacatccata ttccgctgcg tgtcgtgata
    34381 tcggaatgtg atgtgtccgg tgggatgggc gctatcgagg tgagaaatgt cttgggtcac
    34441 ctggtagagg gcagatccga gatctgacgt cacagattga tcggtagtga ccagactcag
    34501 aggacccttg aagcgtcccc cggcgtacac gagctgtacc ggcacggggc cctgatcggt
    34561 tgacgtggta tatcgcttca gctcccagga cttgagcact ccgccgcggt tggagaactt
    34621 agcccgaaac aagtccgtat ccacctcgat cgtctgctct tccttgaccg ttcccgtgcc
    34681 accgtctgat gccccaggtg cggaaggaga acttgtctga gtggaagatg ccggactcac
    34741 ggactgggca gaggcattct cggaccctgc agactgtcgt tccgcgacct gggtattcgt
    34801 cgcgacctgc acaggctcag acggaggcaa caaccccatg cccttcagga ggtagtcata
    34861 gccgataatg acggccagag agacgatgag gaaaacaatg acgcgctttt ccatgaattt
    34921 atgtaccgaa taacacctga ggggttgtcg tcacaaagat caccgtaccg ggtctacgcc
    34981 gccaggatgg aacgggtgac atttcagcag gcgccaacca gccatcgcta cccccttgag
    35041 caatccatat cgttcaatgg cgtcttgcgc atagacggaa caggtcggat ggaagcggca
    35101 tgcgggacca agcatcggcg acacacaggc ccggtagacc gacagcaggc cgatgcagaa
    35161 atacctcacg acgagggatc cccaacacga accaaccgct gtctttgcaa tgtgctgcgc
    35221 catacgcttt gcagctccac aaacggcaca ttcaggcatt gtcgcttcgg gaagacaaga
    35281 aatgcgtgcc ccgcactcaa cgtcggccgc actgcacggc ccaattcgcg gaacaggcgc
    35341 ttcgccctgt tccgccgcac cgccgtcccg aatcgccgtc cgatgacaat ccccatcatg
    35401 gtgtcttggg gcatcgtacc cggacagatc tggagattga acaatcctgt tgaaacacgc
    35461 cgcccattct tcttgatgag ctggatatcc ccgctacgct tcaagaaaaa cgacgcagac
    35521 gcctgccctg ccgtcataac cgacctgtct gcgggttacc aggttcgacc gggcttcaat
    35581 cgtttgaagc cgcatatcgc ccgctgtatc gcccatgttc ttccacgacc aggctaagac
    35641 gacagtatcc acccccggtg actacccacc acctggatgt ttgcctacat gcagattgcc
    35701 tagcggcagg aaagaatcag acggtgaggc gagcgcggcc cttggctcgg cgacgagcga
    35761 tgaccttgcg gccgttcttt gtgctcatgc gcttccgaaa tccatgttcc cgcttgcgct
    35821 tgagattcga gggctgttta aaagtgaacg acattgcgca ctccttctcg agagatcatt
    35881 tttcaatgaa gaggccgcat tataggggcg tcacaggagg gtgtcaatca atctaccatc
    35941 gcctctccgc gatgaaatcg tcccctgaaa tgcagactgc atgaagcgcg cggcctctcc
    36001 gatgcgcaca cgccttatca atcgccactt ctttgaggca ctcttgcccg attgcggcaa
    36061 agatgccaca gcggcgagcc agtaagacaa cggaatactg caccgtaact tattgttctc
    36121 ccaaggcatt caatggtctt cgcacgaatg cactttctgg cacttacatt gcgtaggagg
    36181 atgttggaat gatggaatca tcgaccttca cgcggaatcc atgaaggacc gcggataggc
    36241 cggagccctc gtatcagaag gcaccacggt aacactaccg tccagttagg gacaaaaggc
    36301 gggaagaact cgcgggacag ccatccgcac gctagaatgc aacaatgatg agccgctcac
    36361 gttacatctg ccgcatcgcc actcgcgtta ccctcgtcgc gctgttatcg atgagcttgg
    36421 gcgggtgcgt cgaaaccgtt cctgaggagt tggtggaatc cattgagagt ctcgaccgtg
    36481 acctgtcaac actgcgagcc tccgacgtga accccgcagc ctattccaag ttttcccgcc
    36541 aatggattgc gctacaaggc cgaatccgat ccgaggagaa catcgtccgg tggccatggg
    36601 aagacaatga gctggaaacc gatctggaag cccttcaagt cgagggcacg cagctcctga
    36661 gcgacgtcaa tagccgcatt caggctcaac gcacgactgc cgaaacgaaa ctcgccaaaa
    36721 tcgagcagcg gcttcgcctc ctgaactctc gagtgggaga catcggcagc cgcgtggtgc
    36781 tgggcgagca tccggtcgaa actgaagtgc acgtcaaaca ggctcgcctg ttcctcgaac
    36841 agggacaatt tgaacattcg atccaggctt cggaacgagc cggtagaatc ctcctgactc
    36901 agaccgccct gctcaccaat gagttaggcc ggtatgcgga cgatgatctg atcgcggcgt
    36961 ggcgggaatc ggcacaacgc accattgact ggtctcgaac tcatcgggcc caggccattg
    37021 tcgtcagcaa ggccgaccgc tccctcaccc tatataagaa cggtcgcaaa gttctgacct
    37081 atcctattcg attaggatca agaggaatcc gggcaaaaca gcactacggt gatggcgcta
    37141 ctcccgaagg cgaatatcgc attcaacgta aacgcggacc tggacaaacg ccctatttcc
    37201 gcgccctgat tctcgactat cccaatatag acgaccggcg ccgattcgag gaagcccaga
    37261 aagcaggact catccccaaa agccaacata tgccaggcct cattcagctt catggcatcg
    37321 cgcaaggaat ttcggatcaa ccgtacggca gtatcgtgct ggataacccg cagattgccc
    37381 aactgtttga ccaggtcgcc gtgggcacac ccgtcaatat cgtcggcgca ctggaatcgc
    37441 aaaattccat ttcgctagtc ctggctgact tgggcgatca ggaggaagaa acatagcgtc
    37501 gggcccgcta cgcattagcc ttcggtcgct tctccacctc catcattcat ctctctcgct
    37561 ccaactgact ccgccatcgc gtatcgcctt cccttcctgg tttgcctttt cacatcctcg
    37621 aacctaagat agggctcagc cgaccagcat cttcgttcct ccacctatgg aagagagcgt
    37681 gttatgccga tccgccccaa agtgacctcc cttctggata cccagaccct cgcgacaaca
    37741 ttcgatgaat tggcaagcag tcgcgcgatc gaacggattt tgatgcgaga ccataccctt
    37801 tggaagccga atccgacgga aatcgataac aggctggggt ggctgaccgt actcgaccac
    37861 atgcaagacg gactttccga cttgcgaagc ttcgcccaag ccgctcgaga ggctcgcacg
    37921 acagacgtgg tgctacttgg aatggggggc agcagtttgg gcccggaagt gctgcgctgc
    37981 acctttggat cgtcgaaggg cgctcctcgt ctctgggtct tggattccac cgttcccggc
    38041 tgggtgcgac aggtcaccga tgcgatccaa ccggcacgaa ccttgttcct tgtcgcgagc
    38101 aaatccggcg gaacgatcga agtcatgagc ctcttcgctc acttctggga actcgtccac
    38161 cggacaaaag gccatcgcgg cggagcccag tttgtcgcca ttacggatcc ggcaaccggc
    38221 ctcgaagaac tcgcacggga gcgtggattt tggcggacgt tcactaacca accggacata
    38281 ggcggacgct actcagtgct ctcgtatttt ggattggtgc cggcagccct gcttgggttg
    38341 gacgtgggaa agctcctcac tcgagctctc gccatgcggg agtcctgtcg acatacggtg
    38401 gccaaagaaa atccgggatc cgccctggga ggcctgatgg cggccatggc caaaagcggc
    38461 cgggacaagg tcacccttct cacctcgccc gcattaactt cttttggact ctgggtagaa
    38521 cagttgctcg ccgaaagcac cgggaaagaa gggaccgggc tcattcccgt cgcgggagag
    38581 ccattcgcat ctcccgctgc ttatggagca gatagaattt ttatctcgct tcgcctcagg
    38641 ggcgatcgca atgcctccct tgatagaacg gtttccgccc tgcagcgagc gggacagccc
    38701 gtgtattcca taccgctcaa ggatcgttac gatctgggtg gtgaattctt ccggtgggag
    38761 ttcgcgacgg ccattgcggg acatgcactt gggattcatc cattcgacca gcccaatgta
    38821 caggaaagca aagacaatac gggacgcgtg ctgaaagagg tcgaaactca ggggaaactg
    38881 ccctccattg ccgtgctgcc acccaaacaa gcgttgactc aattgctcga acagatgggc
    38941 tcgaatcgct acctggccat tctggcttac accactccca ccacccaggt ggaagcggca
    39001 ctgcgagcct tacgcaaagc tctcatggtc cgatatcacg tggccacgac gacaggatac
    39061 gggccccgct atctgcattc gacggggcaa ctccacaagg gtggaccgaa cagtgggctg
    39121 tttctcgagc tggtcgatac gatgaagccg gatctggcgg tcccggagaa attctatacg
    39181 ttcggcacct tggctcaagc gcaggccctc ggtgatctgc aatcgttaca cacacaccag
    39241 cgcccggccg tccgcatcgc tctcggcccc aatcccgtac ggaccatccg cagcctcgtc
    39301 actttcctta cacccgccaa ggccacgcgc cggaaatccg tgccaaagaa gcgaaccacg
    39361 tcaactcgtc gatcccgccg ttgagatggc acaccctccc gaacggtaca tctttgctga
    39421 tgcgcaagag gtcgttcgtg ccgcagcaac actcttcgtc actgttggcc aacaggccat
    39481 aagcaagcgt gcacgctttc tggtggctct atccgggggt tccacgccta aggcactcta
    39541 tatggtcctg gcgagtaaag aattcgccac acagctcgac tggaacaagg tgcacttcct
    39601 gttcggggac gaacgcgcag ttccgcctac acatcaggat agtaactttg ccttggctaa
    39661 tactctcttg ttcacaccac tgaatatttc ggccacgcac atccatcgga tgcgcggaga
    39721 ggactcgcct gaaaccgcgg ccattcacta tgaaaacctg ttgcggggcc tgacggccac
    39781 aacgtcagaa caatggcctg tactggacct ggtcctctta ggcatgggag aagacggaca
    39841 caccgcctcg ctctttccag gtacgccggc actcagcgaa ccaactcgct gggtcgttcc
    39901 cggcctagcc ccgcaaggca cgcgatcccg catcaccctc accctaggtg tgatcaatca
    39961 tgcgagtgtg gtactgttcc tcgtgaccgg actgaataag gccaccgttg tccggcgtat
    40021 tttcgaaagt cgtgccgacg cccccgatgc ctatccggcg gcaaggatcc gtcccgagac
    40081 agggcgactg ttatggtatt ttgaccgcgc cgccgcatcg gcattgactg aggcgacaga
    40141 tgagttgtca tcataagggg aaccatgatt ctggcaggtg atatcggcgg gacaaagacg
    40201 aacttggccc tctatgagtg gaccagcggg cgggtcgaac cggtgcgcga ggacagtttt
    40261 cacagcgcgg attataaatc ccttgaagag atcatcgacg agttcctcag caccccgctc
    40321 gtcaaaccgg cgctcgagaa cgctcttacg gaggaatccg tcgaccttgg cagtgatgtc
    40381 gccgctgaga ccgccccagt tgttccagaa cccatcacgc tcacggcagc ctgttttggc
    40441 gtggcgggac cggtcatcga caatcgttgc cgcacaacca atttgccctg gttcattgat
    40501 ggagccgcct taggcgaacg attcgtcatc ccccacgtgc gcctcttgaa tgatctcgaa
    40561 gccaccgcgc atggacttct gcatctgacg accgatgaaa tggtcgtgct gaatgcgggg
    40621 gcgccgccca agaaaaaaca ggcgctcgcc ctcatcgcgg ctggaactgg gctcggtgaa
    40681 tgcatcctct attgggacgg aacccgctat cgccctatgc catcggaagg cggacatacg
    40741 gactttgcac ccaatagcga cagcgagatc gaattgcttc ggcatcttcg cggcagctat
    40801 ctccacgtca gctacgaacg tattgtgtca ggccccggcc tccatgcgat ttacgagtat
    40861 ctccgcgaca cgaagaagaa tgagccaacg tggctggccg agaagatcaa ggtcggcaat
    40921 ccggcagccg agatcgccga agccggactc aaaggccaag cagaaatcgc gacacaagcg
    40981 ctggaattat tcgcatccgt ctacggggcc gaggctggca acctggcgct gaaagccctc
    41041 acgctggacg gagtctatgt cgccggcggc attgctccca aactcctgaa gaaactgcag
    41101 gacggctcat tcatgcgcgg cttcaccaac aaaggccgct acaaacgact gatgaaccaa
    41161 ataccggtga aagtcgtgat gaacgataaa accgccctgc tcggcgctgc ctccgtggcg
    41221 gcacaactca cacttcctcc ttcattatga caacaacatc ctgtgacctg gattcggaaa
    41281 agcgccaagc cgcgctcaag gcaacggaat ttgtccacga tggcatggtc gtcgggctcg
    41341 gaaccggcac cacgtcgaaa catctcatta tcgctctggg cgagcgcgta cgtgcagggc
    41401 tgaatattca agccgtcccg acatcgcacg acaccgcagc cctcgcgaag caatccggca
    41461 ttccgcttat cgaatccgac aatgcctgga tgatcgatgt cgcgatcgac ggagccgacc
    41521 aagtcgaccc tgcattgaac ctcgtgaagg gcggaggggg cgcgctgctg aaggaaaaaa
    41581 ttgtcgccgc cgcggcgaag cgattcatcg tcatggttga ccacacgaaa ctggtgccgg
    41641 cgctcggcgg cagtttccct cttcccattg aagtggtgcc gtttgggtgg ggcagcaccg
    41701 cccgacacat cgaagcggtc tcgggcggca gagcggtctt gcgccaacgt aacggagacg
    41761 tgtttcagac tgaggcagga catgtcatcc tcgatctgca catgcccatc atcgatgacc
    41821 ctgctgcgct ggaagttgaa ctcaatcaga ttccgggcat cgttgaaacc ggcctgttca
    41881 tcggacgaac cagcatcctg atcgtcggtc atggacaagg caccgacgtc acccatgctc
    41941 cgaagccatg accaggccgc agggcgacct gccggtaacc cgccggcagg cggctgctct
    42001 ggccgtacgt gccgctaccc atgcggccct gtggctgggc gcatggccgg gaatcgcatc
    42061 cctggtcttc gtgcctgagg cccggagcca aacaacgtcg acgcacaacc aacaacatcc
    42121 tcacaacact atgacgactt catccgcaat tgctgatccc taccgtctcc cgcgccatgt
    42181 cattccgaca tactatgacc tgcggatgga gccggatctc ccctcacatt cgttcacggg
    42241 gcatgagatc gtcacgctga cggtcactga acccacgact gacattctct taaatgcgac
    42301 ggagctcgag gtgtcggcag cgacattgtc cggcgaggga cagccaccac gcaccgggac
    42361 cgtccggatg gatgatgaac atcagcgatg ccacatcacc ttcccagcgg tcattccacc
    42421 gggtgtgtgg aaattgagcc tcgcatttcg cggaacgttg aacgacaagc tccggggttt
    42481 ctatcgcagc agctacaaag acgatcgagg tatcgcacat agcctcgccg ccacgcagtt
    42541 tgaagcgacg gacgcgcggc gggccttccc ctgttgggac gagccacact tcaaggccgt
    42601 gttcgccgta accttagcca tcgatccggc gttgacggcc atctcgaata ccagaatcgt
    42661 ggacgaacgg ctggagaacg gcaaacgcat cgttcgattc gccgaatcca tgaagatgtc
    42721 cacctacctg gtggcattca tcgtgggcga actggtgtcg accgcgccga tcatggccaa
    42781 acagaccccg gtccgactat ggtccgttcc aggcaaacag cacttgacgc cattcgggca
    42841 cgagatcgcc gtctactcac tcaactttct agccgagtac tacgatattc cctacccagg
    42901 tgacaaactc gatctgatcg ccattccgga tttcgcttcc ggcgcgatgg aaaatctggg
    42961 tgccatcacc ttccgtgaaa ccgccttgtt attggatcag cgcaccgcca cacatgcgga
    43021 gcaagggcgc attgcggacg tcgtggccca tgaaaacgcc cacatgtggt tcggtgactt
    43081 ggtcaccatg gcctggtgga acgggctctg gctgaacgaa gccttcgcca cgtttatgga
    43141 aatgctggta gtcgatgcct ggaaaccgga gtgggagcgg tggacagcct tcggcatggc
    43201 acgcgccgcc gcattatcgg tggatggcct gctgagcacg aggccgattg aatttcccgt
    43261 gcgcgcgccg aaggaagccg aagccatgtt cgacgtgttg acgtatgaaa agggcgcctc
    43321 ggtccttcgc atgctggaac aacatatcgg tccgacagtg ttccgggacg gcgtacgcca
    43381 ctaccttcat gcacatgcct atgggaatgc cgagaccacc gacctctggg tctcccttgg
    43441 ccacgcctcg aaacaggatg tcccggcgct catgaacgaa tggattttct cgcccgggta
    43501 tcccttgttg tccctctccg tcgagtcacg ctccacgttg atgctcacgc aacgccggtt
    43561 catgtacgcg gacgattcct ccacggcacc ctccggcact gcgtcgccac gttggcaggt
    43621 gccggttcaa ctgcggatca acaccgcgcg cggcacagaa accagacgcg tattgctcag
    43681 tgagcgagag aatcgcattc ctcttccaga gggctggacg tcgatcctgg ccaatgaagg
    43741 ggggcatgga ttttaccgcg tgcgatacag cgccgacttg ctcagtgcct tgcagaagga
    43801 tggtctgaac accctgactg cggtggaacg attcaacctg ttgaatgata cctgggccgc
    43861 caccgtcgcc ggcatggtct cctccgccga ctacctcgcc ttgactgaac atttccgcag
    43921 tgaacaggat ccgcatgtct gggctgtcat gctgggttca ttttccacga tcaaccatct
    43981 cctggaagaa gaggatcgtc ccttgctcgc agcgttggta cgcgatcggg ttgcgcccct
    44041 gtttcagcag ctcggctggt cgccccatgc cgatgagcgc gatctcgtca aggaattgcg
    44101 cggtgatatc attcgcgcgt taggcacctt gggacgtgac gaaaccattc aggctcaagc
    44161 gcgggaggcc tacaccgcga ttcagcagaa gtcccggccc atcgatccca atgtgattcc
    44221 agcactcgtt tcgattctgg ccttcaccgg ggatgaggct cgctacgaag aattttcagg
    44281 ccggttccgc caagccacca ctccacaaga ggaacgtcgc tatctctttt ctctggccgc
    44341 gttccgtcga ccggagctgc tggaacggac gttaacaaaa accctgaccg acgagatccg
    44401 tacgcaagat gcgccattcc tcgtcagcag cctgcttcag aacgtgtata tccgcgagaa
    44461 ggcctgggaa tttgtgaaga ccaattggga gcggatggac aagctgtttc cgaaaagcgg
    44521 tttgcggaga atgtgcgggg gcctcaccgg tctctcaacc cctgaactgg aacaggacgt
    44581 ccggcacttc tttacgtccc gcaaaatcga tctcggcggc aagacgctgg aacagaatct
    44641 ggaacaactt catatcgccg tgcaatttcg cgagcgtgag cgcgaagcga ttcgcgccgt
    44701 gttagcgcgt aggtcgacct gattcaatcg gagcttctat cgcaccatga tcattcgtgc
    44761 cgaagcacgg tcaggggggg ctggcctaga atgcggtagg tactgaggaa tccgaccagg
    44821 agcgtcagca gaacggtaca gcccaatccg atgcccagca cgggcagctc caacgcccac
    44881 ggcagttcca ggatatatcg taagatcgcc catgagaaca gactggcaag ggcgacgccg
    44941 atcattcccg ccacacatcc gagcaacgca tattcagctg caaatgaccg ggcaatcaac
    45001 ccgcgggttg cgccaagcgc cttgaggatc accgcctcat acagccgccg atagcgcgtc
    45061 gccgcgaggg ccgccgccat caccagcgcg ccagccatca ggcaaaagag cgcgacgccg
    45121 cgaatcgcca acgacaagcg gtcgagcaca cgggcaaagc tgttcaatac ttcgccgatg
    45181 ttaatggcgg tcacattggg aaacgcagcc accacggccg actggaaggc cacttcgtcc
    45241 tggggagcca ctcgcacggt ggcgacgtat gtcatcggcg ctgcatcgag cgagccgggc
    45301 gaaaagatca tgtagaaatt cgtggaaaag ttcccccact cgaccttcct gatgctgctc
    45361 acttccgctt gtagaatggt tccttgaatg ttgagatcca gcaggctgcc gacatcaaga
    45421 tcgagactct tggcggcttc ttcctcgaca gacacctgcg gtttcgaaaa cacctgcccc
    45481 ggtttccacc aggcgccttt cacaatctta ttatccttgg gcacttgatc gagaaacgtc
    45541 agcacatact cacgagtcac ataccagctt ttgcgcttct cttccttcga ctgagcaggc
    45601 ggttcatcct gctgagcctc gcgctcgtca gtcaccggcc gcccattaat ggcatggatt
    45661 cgtgagcgca ccaatggagt cagatcggga gcaaaatcgc cggtgcgccg atggactaac
    45721 tccccgaagg cttgtgcctg atccggttga atatcgatga aaaagaaggt gggagaatcg
    45781 gacggacggt tttctcccac ctgccgcacg agcgcatgct gaagcaacgc gatcgccagg
    45841 atcaccatca cgccgacgcc gatcgacacc atcacgccta gggtttgccc cccgggtcgt
    45901 tgaatgttgc ccagcgcctg ccgcaaagac aactcccgcg gtacgggcaa cgcgcggagt
    45961 ccccgcaaca atgcctgggc tcccaaggtc aagaccgcta tcgcgatcac caagccaccg
    46021 ataaacagtg cgccgatcgt cagcgatccc gcctgccaca tagacaagct cgccagcccg
    46081 atcccgatac ccgccgccgt gacggttcgc aggggatccg ccgtcatcac ttgtcccgcg
    46141 cgtttccaca aggctttctc tcgtcgcacc agtggcgcac caacacgttc cacttcacgc
    46201 ctgaaaatgg cagcgggttt gatatctcgg atagtcagca gcggccacac gctgaacaac
    46261 agcgtcgtca ggatgcccaa acccaagcct ttcccgatag gggccacggc tgaaagagag
    46321 agcaccgatg taaactcgac ttgctggagg acatccgtcg ccaacaacgt ggacaccgcc
    46381 tgcggaagga ctgtttgcaa ggccacgccg atgccgatcc ctcccaggct acccaacagg
    46441 cctaagccga cggcctgccc taagtaggaa tagattatgg ttgcggtatc cgcccccacg
    46501 gttttcaaaa tcgcaatgga ggggagcttc tctcgcacga acgcatgaat ggatagcgcc
    46561 acgccgatgc cgccgacgaa cagcgccgtc agcccgacca agcctaaata ccgcgcgagt
    46621 tgatcgagaa actgcttgag ctgtggctgg gcatcgcgat aagaagacac ccgcgcggat
    46681 tcgacgccaa ggcggccccg cagctcatga aggagcgggg acagtgccat agaggcagga
    46741 agccgtaaca aatgccgttc acgcattcgg ctgcccggct tgatcagatc ggcggcggcc
    46801 agcccttctt gcgaaatcag cacccgcggg ccgaggctga acatgttggc catgcgatcc
    46861 ggctccgtat gaatcacgcc cgtgatccgg aaagaagcct gtccaatctt catcgcatca
    46921 ccaacgccta agcccagccg gatcaacaat gcttgctgca cgaccgcccc gtgacagatg
    46981 gttccgcaac ggtcaccggc cggatgaagc aattcggtca atggtcgatc cggctcaacc
    47041 cgcacgacgc catacagagg atatcgcggc tcgacggctt tcaattcgac gagctgcgtg
    47101 acgtccattc cgccttcgcg acggtcgacc cgcgccacca tggcgaccag ctcatctaca
    47161 cgcgtgacct caattccgcg gcccgtcagg tccttgagca cggtggagcc cggtccccct
    47221 aaaggcctgg atagccggat ttccagatca ccacccagca ggccccgtgc ctctttcagc
    47281 accgcgcgtt cgacgttggc cgaaaagaga gacaccccca ctaccgcccc gacgcctaat
    47341 gcgatacagg cgagaaaata gacaaaatgc cgccaggaag atcgcaagtc ccgccaggcc
    47401 aggatgaacc agaatggcct cataggcggt cgccggactc gtcgtaggaa gatgccatga
    47461 attgatcaga cccgatccgg ccgtctcgca aggtaataac ccgctccatc gaagcggcta
    47521 gttgttgatc gtgtgtgact aacacgaggg tggtgccggc gtcccggtgc aacgccatga
    47581 tgagctggat cacctgctgc cccgtatggg agtctaagtt tccggtcggt tcgtcggcca
    47641 acagaatcgg cggccggcag gcaaacgcac gcgccactgc gacccgctgc tgttccccac
    47701 cggaaagctg aaccggatag tgcgagaccc gatgccctaa gcctaccgcc tccagcaatt
    47761 ccatggcgcg ttggcgtgca tgacggtcgc ctgcgagctc caacggaatc gacacgttct
    47821 ccagagcggt taacgtcgga atgagatgga aggactgaaa gatatatccc acgttggcca
    47881 ggcgcaggcg cgccatcgcc ttttcgttca gtcgggtaat ctcccggcca ttgagccaga
    47941 tggttccgga cgtcggccgg tcaagccccg caatcaggcc cagcagagtg gacttgccac
    48001 tgccggacgg cccgacaatc gccacggttt gcttctctgg aatctcaagg gtgatatcat
    48061 ccagaatcct gaccgtctcg cccccggcct ctaattgcat cgtcacctgt tgagtggcaa
    48121 tcatcatcct gttgatccgt agactccaca tgcaaaaaca gttttcatat tatactgtac
    48181 gcatgacgac ctgctcggac cttttccgca tcatcccgcg actgatgaca ggcagcctta
    48241 tcgtcctgct cgtgagcggg ctcgtcggct gcgatcaatc tcccctggcc tctagtcctc
    48301 cctcatcatc cgcgcctgcc agccttgccc cacctcagcc ggcgactgac gacaagcctt
    48361 cagcgggccc gccggctacg acgacggtgc cagaggccga cagccgaccg agaatcgtgg
    48421 cattcggcaa tagtttgact gccggcctgg gcgtctcccc cgaacacacg tatccggcgc
    48481 agctgcagaa acagctggat acactcggcc ttcactatca ggtgctcaat gcgggggtga
    48541 gcggagacac gaccgcagga ggactgcgtc gagtatcctg gctcctcgcc ggaaaaccgt
    48601 ccgtcgtgat tctcgaatta ggggggaatg atggattgcg cgggttgagc ctgccggaaa
    48661 ctcggtcgca cctggatacg attattaaac gattgaaaga ggcgcgggta caggtgattc
    48721 tggccggcat gaagctgcca ccgaactacg gcgaggagta caccacacaa tttgaagcga
    48781 tgtatcggga cctagccaag gcccatgcgc ttgcactgat tccgtttctt ctggaaggag
    48841 tgggcggcga ccagaagctc aaccaagccg acggcattca tcccaccggg gaaggttatc
    48901 ggattgtcgt tcagaacgtg ttgcaaaccc tgcttccgct gctgaaatcc ggcgagtccc
    48961 attccccgac tagcaaaaag aaggcgtgaa acatcccctc cgccttccgc aacggagaaa
    49021 cgtttcacgc cacttgatcc tgaggagctg gttagctctt cttgaagaag gtgtcgtaaa
    49081 ccccgaacgc caagatgaga gcaatcagga cgtagtacag gcccgtgatg ccactgtaat
    49141 ccggtggccc ttcactgacg ttggccaagg cattggtcgc ctggagcgcc ccgattccac
    49201 ccaaaactcc tgctatcagc ttgttcatga tctccccctt gtagtcaagg aatccccaaa
    49261 gaggcccgca ttgtactgaa cggactgggg atgacgcaag gggggacaga aagaaggatt
    49321 cgattcggaa ttggaagaga cagggccggt ttgaaggcgg aagtagccgc tacaccttcc
    49381 ccagggcttt caacatcgtg gccacatctc gacaggtatc ggagaggcct tccaaacgcc
    49441 ggcctttctc tgtcaaaaga ccggcgatgg cccgcacttc gccctcgaat tgttcgacgt
    49501 gtcgtgacaa ctccgtggat ttagacaggg aggccttatg ctgatccacc tcccgctgga
    49561 gatcccggca aatcacctgt aaggatttgg cttcctttgc ggaggcttcc aaatcttgag
    49621 tcaggcgggc gacgaccgct tcacgattgc gaatatccgt atcgagttca atttgcgcga
    49681 cttcgctttc ccgccgtcgt tcatccaatt gctgaatgat ccgggtccag gtcgagacca
    49741 ggcccggctc gatatcgggc tgtgcaggaa ccggctgacc ggattgaata gcctgcacca
    49801 ctcgttgcat ccagtcgctg aactgattca actcgctgag tttcacatcc ccggagggag
    49861 cggatttcgt ggttgcccgt tcggcttcaa gacggggagc tgcaggtcgc gccctgggga
    49921 ccacgcgagc cttcgaccat cgttgatatt cgagcagcgc agcaacaccg tgccggcaga
    49981 tcggttgctc gtggagggta caggagcact tggcctccag gtgcccgtta tggagacgga
    50041 tggtctgctc gtacagcccg gaattgccca tcacagagga ggtgaactcg gtatccgagg
    50101 cgtcggtcag ctgcacccgg cgttccgtct ggtattgcct tccgatttga aacgcattgg
    50161 gctccacgat ggagctgatc atgtccgcct ccagtaaact gaggcgatcc gccgaacatg
    50221 cgattttccc ccgcatcgtg ccacctgtgg aatggttggt tccagtgagt cgcccttgca
    50281 acttatcgaa tgatcgccgc agtgtcatgg aatgcttacc cctgaggccc atcatccagg
    50341 catgggaccc gagtgtacgg caggttcccc gatccgacca ttccggtgac ggagccccct
    50401 gcaggggtcg acagaatacg gcagggccgc gaggactcga ccgcccgata tcttatcggc
    50461 atcggcgagg agccccttga gacccaggcg gggtcaacca cacaaaatct gcaatacctt
    50521 cctgcatgga ttgatagagc tctgcggccc ggtcctgctc caacgtggcc atatagatgg
    50581 tcacctgctt gagtccgtgc tcaacacgcc gagcgacgcg attcggtacc ggcaaccgat
    50641 attggacgtg tccgccgccg gtataactca ccaccggccc ctgtgtcggg tcgcccgcag
    50701 cgcgaacacg attcaccgcc gccgcgacgg tcttcgccat gccctcgtcc ctcaccatcg
    50761 aggcgtcgta catggtctga tagtcttccg gtgccccccc tccgtggcag gcctggagtt
    50821 gagatagaat acgggagcga taggccgggt catcgactat cgtctcctgc tccatgcccc
    50881 gttgacgcca ttcgggctgc tctttggctt gggccagtcc cagcttgacg acctgacgaa
    50941 tcagcgtttt gggaggattc atggccagca ccgggagccg ctgatccttg gcaaactgca
    51001 cgagcggttc ataatcctca aaagcgccac cccagttttg tttccatccc acacgctcga
    51061 gaaattccgg gcgagcggat tccttcgtct cgagataggc atccagagcg ggctggcctt
    51121 cccagccgaa catctccatc gcgagcacag gccgacgccc gcgggtcaca agcgtccgca
    51181 gcaccgtcag cgcggactcg atgtgggatc gattgtgatg ctcctcaccc aagtagatca
    51241 cgtcatatcc ggccaaccct tccaaccact cggccgttga aacgacgtgg cccgtcttgg
    51301 catccagtat ctgaccgaca gaccatgcgt cccagacttg cggggttacc cggggcacag
    51361 gcccggccgc ctggcagcct cccagagcga ccaccaaaac caatatcgcg atgacaccgc
    51421 tgaggttgtt caagaccttc tcacgtaaat gctgtaatga tgtacgcata tcgtctacct
    51481 aacatacgca ttatgcagcc gcaagacgac ctgcttgact cctttacaac cggcccgata
    51541 ctctgcgcga cgcaacggaa cggtcgatca cccacaaccc acacgccggt cgttgactcc
    51601 tgatgcctgt tgattccgac agcctggccg cattccggaa acaggtcaca tccgccagat
    51661 cgctcgatgc gccgttatgg gaggcctcgc gccacctcgt acattcggca gactggcccg
    51721 caaccaggac agccctcgtc aaggcgatcc acgcttcttc cataccagac ggactgaagc
    51781 agactctggt ggcggcgtta ccagtggatc tcgcgactga agatcgcact tcttccgctg
    51841 tgctcctcaa gcagctcacg gggcttcccc tcacaaaagc tctccgggcc ttatgcgtgt
    51901 tctttcaggt cggacgacca gcgatggcca aatggcccct gccgaccgtc acgccagaca
    51961 cgatcgacag attcgtccag acgcatcaca atccattcga tgtgttactg gagcaacttc
    52021 cggcctcgtt gttagacctg ggagcagggg atctttcgtt tgcggaagaa ctggccacca
    52081 tctatgaacc cccgttgacc gcgcaacaca gaccactcct actccactgc ctcgaccggc
    52141 tggatccttc ctcccaactc ggaggaccat tacatgcccc tccgcttcga ctgaatcgcc
    52201 tgcgcagcaa gcccggtctg gagttccgct tctatggcga tcaggacatg ttcgccctcg
    52261 actctttgga acgggatcag cgcttggccg cccgatatct catcgtcacc tgttgggccc
    52321 cggctacgcc gacctttgcc tatgaaccaa ctcgcctctc tgcccgctgc ctcgccgaag
    52381 agctccgacg caccaaggga gattcccgcc agattcgaca tggcaaagaa ccggccctcg
    52441 aggtgagcca tgccggacga aacttactgt ttccaccgtg gaagttcgat attcgtgggc
    52501 cgctcgccct gctggaattg atggccagcc gggcagccct ctgtgtgttg ggggcggtgg
    52561 actcgcaggt gtgttgggaa attctctcgc aactgatcga tgacccgcgt gtcagacccg
    52621 ccgatgtcgt gttgtcggca gaaacgctgc cagcgatctt cggggaaacc taccgccaac
    52681 tctcagctct gccggtgggt ggctcctgcc tgctatcgga cctgacgccg ctgcggaaga
    52741 gttttccgtc tgttctgcac acctctcccg gtcatcctgc cccctatcga ttccggcagg
    52801 tcaaaattca gcgcggtgcg ctattcgcag gactccctgc cagtagcaca gcgaggcggt
    52861 tccaaggcat gtctgaggaa acgcccccct ggttgctgac gctcgtaccc gagcccgtcg
    52921 ccatttcctg atactcgcct ggttcccgct ctggcgcctc acaaatcgat caccgagcca
    52981 ccccgcatga aaggccgtat aaattgacgg tctccagacc ctttgttaga cttcgggcat
    53041 acacgccatg tgcccaacat aacccccttc acaaacaaac ccatcgtgaa ttcttctcaa
    53101 tctatcaaac tgttacagga caatatcgcg caggtcatca aggggaaggc gcgggcgatt
    53161 gaactggcgg tcgtctgtct cttggcacgg gggcatcttc tgatcgagga cgtgcccggc
    53221 gtcgggaaaa cgaccctggc ccacagttta gcccgttccc tggactgctc cttcaagcgc
    53281 atccagttca cgagtgacct gctgccttcc gacatcgtcg gaatatcggt cttcaatcgt
    53341 cagaaacagg cctttgagtt catgccggga ccgctcttcg cccacatcgt cctggccgat
    53401 gagatcaatc gcaccacgcc aaaaacacaa agcagtttgc tcgaagcgat gagcgaggcc
    53461 cagatttctg tcgacaatca gacctatcct cttcaacagc cgttcatggt cattgcgact
    53521 caaaatccgg cggagtatca cggcacattt ccacttccgg aatcgcaatt ggaccggttc
    53581 cttatgcggc tgtgtatcgg atacccgaca ccagaagagg aaaagaaggt gctggaccga
    53641 ccgccatcat tgcacccggc taacgaaatc gagccggttc tcaacgcgca gcatattctg
    53701 gatcttcaag cccaggtcga taaagtccga atggaagaca gcctgatgga ttatctgctg
    53761 gctatcgtgc ttgccaccag gcaaaacccc ttattttcac tgggcgtcag tacgcgcgga
    53821 gcgctcgcgc tcagcaaagc ggcgaaggcc ctcgcccttg cgcgagaccg aacctattgc
    53881 ttgccggaag acattaaaga actcgctccg gccgtcctct cgcaccgcgt tatgctcaac
    53941 cgatctcagg gcgcacgcac gaagagtgtc gagcacaccg aacgggttat tcacgacatt
    54001 ctggagagca tcccggttcc cgtgtgacca ccctgcacac gaagcaggct atcggataac
    54061 ggccgccagc ggccgctcat gggatgacgg gccaccagca tggctttcat aactctccgt
    54121 acctggcttc accagctctc cagacaccgc gcgatcagcg tcacaacgga aggcgtacgc
    54181 tttctgctgc ttaccttggc ggttggtatc gctgccgtca atacgggcaa caatctgttc
    54241 tacctgttgc tggcgatgat gctcagcctc atcgtgttat ccggcttctt gtcggaacaa
    54301 tgcgtgcggc gactcgagtt ccaccgccat ctgccggaca cgttgtttgt caatcagcag
    54361 gccaccgcaa cgttgtggat tgccaatcgc aaatcccatc ttccgagcat ctccttgcgc
    54421 ttcctcgacg tcgccgccgg ccaggatcat gagtgcggga tccatctgac tcaccttgcg
    54481 ccgggcgcgt cgacgttgcg tgcgtacccg ctgctcatca aacggcgtgg ccgctgtcaa
    54541 ttggacggaa tccgagtcgt cacaccgttt cccttcgggc tgtttcataa gaaagcgttc
    54601 tatccgctgg aggccagcgt catcgtctgc ccggcactca ttccgcttcc acccatgcag
    54661 gtccaggcac tacacgcgat cggccatgat cacgccttgg ctcgacgtgg ccacggaaat
    54721 tcactctaca atctgcggga gtttcgcccg ggcgacgatt cgcgagccat ccattggatg
    54781 acgaccgcac gaacggccaa actcatgctc aaagagactg aagccgaaga ccaacgcatc
    54841 atcacgcttg cggtctttac ggtggcagcg gacgcagaag tgacaacatt cgaacgggcg
    54901 ctctctatcg ccgcttcttt gattgatcaa ttgctgaaga gcggggttcg ccttcgcctg
    54961 ctgctgggcg atcaacaaga agtcatggcc gagggaaacg agtcaccgct tcatctgttc
    55021 catgccctgg cactctgtga gcgaaggccc gtagacgaca gtacagccgt ccagcaggcg
    55081 ctgatctcaa ctctcgtacg gtcccaggat ggccccacgc tcttgatagc atcatgggca
    55141 gacccggccc tccaggatct gtttccaggt gtggatcaaa ttcttacccc tcacacgcac
    55201 aaggacctct tcgatgccga tggatcaggc cttccggctt agctccattc tcctggctgg
    55261 gaccggcttc gccagcctga cactcgccat ggccttgccg ttgtggctct tagtcctggc
    55321 ggcgggagcc ttcggcatgg cattgctgcg cgtccagtct tcaggcgcga tctccggtgc
    55381 catcgggcat ctgcggttct cagcgctcac gtggaatatc tttctcctgc ttgcgttcgc
    55441 cggattctgg atcgacctct tcctcatctc acaggagatc cttccggcag gcattcactt
    55501 tcttgtcctg ctcctcgtca acaaactctc gaatctcgat cagcgacgcg acttcctgca
    55561 tctctacgcc atcagcctga tcgcactcct ggcctccgcg gcgctgacga cgcaaatctg
    55621 gtatgccccg tttttcttca tctacctggt catcggcgtg tggacgcttc tgctctacca
    55681 cctgctgcag gaacgggaag agctgaccga accggaacca gggcacgctc acgccgagcc
    55741 gtcacccgtg ccccttcccc gccttacggc ccggtttttc tggaccacca acgccatggc
    55801 ggcgagcgcg tttggtctca cgttgctgtt cttttttctc atcccgcgag tgggagtagg
    55861 gttttttcaa aacaatcatg gagaaaacct gcgcacgaca gggttttcgg agcatgtcga
    55921 cttgggagtg atggggcccg tcaagcagga ccccagcatt gtcatgcgag tggaactccc
    55981 tgaacgcaca ggtcacgacg cgaagtggga gccactgtac cttcgaggcg tcgcctacaa
    56041 tcggtatgat ggaaaatcct ggagcaacag cctgccgcac cgccgcatgc tcacggagct
    56101 tcccgaaggc accttcacgc tccgtacgtt agcctccaaa ccatcacccc cggctcgcca
    56161 gctcaaactg gagatccttc ttgagccact cgacaccacg gtcctcttcg gcagcccgtt
    56221 tcccacggcg gtcaaaggcc acttcctctc cctccaatcg gatctgatgg gctccctgta
    56281 tctgccgttc cccctccaca cacggagcca atacaccgtc tattcctcac cgaccagctt
    56341 gaatgccgcg gagaaaaaat ccgcggcgtt gatctacccc gactctattc tgcaacaata
    56401 tctccaggtg cccgcggtga atgagcaggt cctcgaactc gcgcgccagg tcacgcgtcc
    56461 tgcaaccagc gtcgcccaag ccgtcgccat ggtgcacacg catttgctga ctcattaccg
    56521 atacaacctg gatgtcccct cgctgcagtc tccgcatccg ctcgaagact ttctgctgac
    56581 tcgaaaaacc ggctattgcg agcactatgc gacggccatg gtggtgatgc ttcgctccgt
    56641 aggcatcccc gcacgcctgg tgaccggatt tctcgccact gaatggaatg aattcggcgg
    56701 gtactacacc gtacgtcaac gagatgcgca tgcctgggta gaagtgtatt tcccccaatc
    56761 aggctggatc accatggatc ccaccccgcc ctcgccgaat gcagtcggtc cgacctggtg
    56821 gcaatcggcc aacagtgcga tggattcgat tcgcctccaa tgggatcgcc tgttcgtcca
    56881 ctacagcgca catgatcaat tcaccgtggt gcaaggcatt cgagaaggcg gagaagccgt
    56941 gcgggcagga ttttccgaga cgttgagcgc cctgtcagcg cagggtgtcg ccatcgtgag
    57001 tcatatggtg atccgcttga ctccctcggg tgttccgcac gttgtgatcg ctcttgtgct
    57061 ggcagccgcc gcagtctatg gagggatagt gatcttgcgg aggttccgga cgaggaccac
    57121 gccacgcagt ccattttcaa cgcagcaaca gaccgtcatc gcgctctaca ccaccatgct
    57181 gcaatgctgc gcgcagcagg gaatcacgaa accggccagc gcaacctcag tagaatttct
    57241 cgaacagatt cggacgcgat ggggcgaggc ttggcctctc gttgactccg tcacgcggct
    57301 gtatgctcga gtacgattcg gagaagcggc gctgactgag gcagacctcg cgacggcaga
    57361 agtccagctg cgcacactcc gacttctcaa acgcaagacc gccgactcgc agtaaccagg
    57421 gcactcacgc ctcaatccat caagctagtg ctacgtgaaa ccaccggact tccacacgcc
    57481 aggcgaaacg gaaggaagtc gttgtgatta aagaactgct cgatgccgaa cgagtcttcg
    57541 tcattgacca ttttctttcg gaggaagagt gtgcggcact gatccggcgc agtgaagcag
    57601 cggcctatga acctggaacc gtcggtggcg tggtgaatga aaacttccgc aataacgagc
    57661 gggtgatcgt cgatgatgag tccctcgcgt caaacttatt tcaacgcgct caacccttcc
    57721 tcccagccgt tcttgatggc catcatctcg tcggcttcaa cgaacggcgg cgattttatc
    57781 ggtatcaacc cggccagacg ttccagcctc atcgcgacgg ctcctatctg cggatgaaga
    57841 ccggagacaa aagtgaagtg acgatgatga tctatctcaa tgatgggatg gtgggcgggg
    57901 agacgaagtt ctatgcgagc gccgaccatg cattcctgca acctcctgct ccgtatctgt
    57961 cggttcggcc gaagatggga atggcgcttg tatttctgca tgccatttgg cacgaaggtg
    58021 ccgtggtgca gagcggactg aagtacgtac tccgcacgga tgtcttatac ggtttgcact
    58081 ctgccgagtc ccgccagggc tagctatctg tccctactta ggggcgtgca ttgccgcatg
    58141 taatgcccaa accggtgcac gtgcacgagg aacgatcaat gacaaggaga tctggaacga
    58201 tcttgcgtgg agataattga aaaattggag cgggaaacgg gatttgggat ttgaacccgc
    58261 gaccctcccc ttggcaaggc ttcctgagtt gttagtatgg aaagagaccc gtagtgacag
    58321 aaggttgatg atcatagacc agacggctcg ttctccaatt tagtttgtaa tgtcgctatc
    58381 cctagacaac tgaggtatcg cgaccaaaac gtgtcacaca ccgtgacctg aaccgtgccc
    58441 cagcttgccg gccagttaca cctaagattt gtgctcgaga atcactccaa caagtctcga
    58501 cacttcgtcc aaaaggcatt ccgccacagc gctgttagcc gctgcagtat aatgccagcc
    58561 gagggtaaat cgactagtcg catttacaag ctccaaacaa gccgtcagat caagaaattt
    58621 cacccctgct tcctgcagca ctcgcctgcc taaaagctgc tgttcagatg gcgagcgaac
    58681 cgaatgacgg aattcaccat attcaggcaa aaagaccact aatggcgtcg agcctgttgc
    58741 ccggaccgta tcgacaaatg acttcagaat cgccttatcc accctctcaa cgtctggggc
    58801 caactcgtag ggggaccata gagacgtggg attccatgat acggcgaatc ggagcaggta
    58861 agaatattga taaagatgcc acttccagtc cgctgggcgg taggcaatat cgaagtccac
    58921 gaacggcaag tcttcaatgg atgaagtgga ataaatccgc tcaggagatg gcaacgggag
    58981 attgagagcg aaaggttctt ctccgactac tgagagtctc ggtttggctc ctggcaccct
    59041 gccaccttga aatcctatta gatagtagac gagaccgctt cgtacaagat cgtggctgat
    59101 cagagctaga atgacgatat cagggtgcca atcctggatg tctcgcagat aacggaggta
    59161 ggactgatct aaaccatagg caggcactcc aaagttcaag acctggacat gttgaccaat
    59221 tctgctctca agctgatggc cccaagtttc gtcgtaagtg acgtccagtc cataggcata
    59281 cgagtttccc gagatggcga tgcggagagc gggggcggtc gctttcgggt cggtttcgtt
    59341 cgccaaggtt cgcagcccat aggcgttact gaagtacatt tccccgaaaa tcccgatctc
    59401 cttccggttc gggcctatcg tccaaccgag tgtcgcgtcc ggctcgatta ttgtggattg
    59461 ttgacgagac ctttcccaat ctgcaagtcg gtgagcctga acccgctgcc attcccttgg
    59521 caacaggaca gtgtccccca cgaacgtttc ctcgggagtc tgttcggcta cgacccgtat
    59581 catcacctcg gccccaagaa agagcaacgc caaagcaata cccgtagccg tcagctgaag
    59641 agtaaaagct ttagaagcga tccgacgagt gtgtcggtag tgggcgctca aagaaataca
    59701 ggcgagacag aagacagcga tgataaaaag taggcctcct gcatgccata gatcaattcc
    59761 ctggtgttgc agacgataga agatcacgat gaaactaaaa aaagaggctg cgagcccgca
    59821 aagggcaaca ggtagggata ccaatgaaat catgtctaaa ggcttatcaa aagaccggaa
    59881 aatttgaaag aggatgaacg ccttcaaacc gataggcgat gaaccttttc ccattcgatg
    59941 ggtcaagtgg ctcacgcctt tcagcaaagg cctggtctga aatcctgaac cgtgcccact
    60001 ttgccgacgg cgggtagact tgcggtgatc ctgttagacg cagggcaggg tgggtccacg
    60061 gccttggccg caggcgcaaa tgcatgctgg atttttgggg aaatgataaa agagcgttcg
    60121 gttaagcggt atgagtctct gcgcagcgcg atattcgttt ggcactcagc cgcccctgca
    60181 cgccgtgact atttgatgtc tcgaggatca actctatcag gaaggcatac gatagtttac
    60241 ttaccgatca cagtcttctt gcgaattgcc atagagtctc tttatagcgg tcttacacga
    60301 ctacttgtcc gtaaatgcat ctgactgcaa gcacgaagag tcgcgctcaa gtgtccacaa
    60361 aacccacgcg cacgttagcg ctaacggtgt tcctggtaac ctcacgcgag cattcagact
    60421 cggggcaacg aaggcagcgt tgagcgattt ccgctttcac gatttgagac acacctttgc
    60481 cactcggctc gcacaagctg gtgtcgattt gtacaaggtg caacgtctgt tggggcacaa
    60541 aacagcagct atgacgcagc gctacgcgca tcattcgccg gagagtttaa gagagggagt
    60601 gttgattctg gagcgcgttc accctcagat atcacaaaac tatcacaatg agggtggaac
    60661 cgtcggagag tgttgtgcaa gtgcttgaga aaattggagc gggaaacggg atttgaaccc
    60721 gcgaccctcg ccttggcaag gcgatgct
//
LOCUS       DAOQPD010000013        60742 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_174_length_60742_cov_20.743652, whole genome shotgun sequence.
ACCESSION   DAOQPD010000013 DAOQPD010000000
VERSION     DAOQPD010000013.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 60742)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 60742)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60742
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_174_length_60742_cov_20.743652"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1550)
                     /locus_tag="PK063_04975"
     CDS             complement(<1..1550)
                     /locus_tag="PK063_04975"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ96429.1"
                     /translation="MMPAKQPKLLLVDDHEANLVALRTLLSQDGVEVLQAGSGREALE
                     MLLDHDVALAIIDVHMPIMDGFELAELMRGSRRTQHVPIIFLTGESQDNLHRFRGYQA
                     GAVDFLYKPIEPHVLRSKAAIFLDLFRQREELARQRDRFLTLAEEKARLLRERDEADQ
                     RLRDSESRFRLLADSAPVIIWMNGLEGVEFVNQACLNFFGVATVEEASKLSWLHYVHP
                     DDQAQAADTYRRAVAERLRFETSFRCRRGDGVYRWMRTIGMPTLSPSEQLLGYIGASF
                     DLTESKEAEERLQRWSVDLERAVNQKTDELRRSQTQLRALATELNLAEQKERKRLATE
                     LHDYLAQLLVVVRMKLRQAIPGASGDRTAELLQDADQALTQSLDYTRCLVAELTPPTL
                     KEFGLLESLTWLAEQMQRHGLPVAMQQQMAALALPEDQAVLLFQSVRELLFNVLKHAK
                     ATQATVTVRIAEHHRLEIIVSDDGCGFVSTPSDHQGSGAARFGLFSITERMAAMGGDL
                     LIESAPGQG"
     gene            complement(1547..2149)
                     /locus_tag="PK063_04980"
     CDS             complement(1547..2149)
                     /locus_tag="PK063_04980"
                     /inference="COORDINATES: protein motif:HMM:NF013502.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheB"
                     /protein_id="HMZ96430.1"
                     /translation="MSVLQHDLSLLDIEAIVIGASAGAIASLTQLLPPLGQDYPLPIL
                     VTVHVPPDQPSSIPSLLQAKCRVTIKEAEDKEFICPGAVYFAPPDYHVLVEKDRSLSL
                     SNEEPVSYARPSIDVLFESAADVYGKTLLALILSGANHDGAQGSRSVVKAGGTVLVQL
                     PESAAARVMPEATLAACPDARAMSLSDINQLLASREPRES"
     gene            complement(2146..2985)
                     /locus_tag="PK063_04985"
     CDS             complement(2146..2985)
                     /locus_tag="PK063_04985"
                     /inference="COORDINATES: protein motif:HMM:NF013867.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CheR family methyltransferase"
                     /protein_id="HMZ96431.1"
                     /translation="MTPDTTVSTEDIELRLFLEAMYSRYHYDFRGYSKASLKRRLLLA
                     CERMGFPSLSALQGQLLHDDTMLPQLLSYLTVQVSDMFRDPGYFRAIREQVIPHLKTY
                     PSLKVWVAGCSSGEELYSLAILFREEGLEEKTMFYATDINGAALAKAEAGVYDLQRIA
                     LFTRNHRLSGGTGSLSEYYNAAYGAACFDKTLRRRTVFSDHSLASDSVFAELHLISCR
                     NVLIYFDRPLQDRAVGLFKDALVRNGFLGIGARESLRFNAHAKAFREFLPVERIYQKR
                     SDL"
     gene            complement(2982..>3971)
                     /locus_tag="PK063_04990"
     CDS             complement(2982..>3971)
                     /locus_tag="PK063_04990"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ96432.1"
                     /translation="LKSDVRTRHIPVHVVSGHDYEQAALSLGAVGYLLKPVQREQLVE
                     AFRQFESRLTDKPRRVLIVEDDKTQRESLRLLLGSDEVETVGAESVAECLACLSERTF
                     DCMVLDITLPDASGFSLLETLSREEHFAFPPVIVYTGRDLSSDEEHRLRKYSHSIIIK
                     GAKSPERLVDEVTLFLHQVVTALPPEQQRMLEKARKRNAVLEDRRVLIVEDDVRNIFA
                     LSAVLEPHGAKIEIARNGRECLTLLEQSKEREKRRIDLVLMDIMMPEMDGLTAMRAIR
                     EQPEWRKLPIIALTAKAMKNDQEQALAAGANDYMAKPLDVDQLLSLVRVWMPR"
     assembly_gap    3972..4071
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<4072..5848)
                     /locus_tag="PK063_04995"
     CDS             complement(<4072..5848)
                     /locus_tag="PK063_04995"
                     /inference="COORDINATES: protein motif:HMM:NF024583.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ96433.1"
                     /translation="MIRFQQKPNPIISGSIALSMAMVLVADFYTPLGITVWVLYLVPL
                     VLSYLTWSPMVPVGVGATVSLFTLVGLVISSFGIDPSLSLINRAMGIVTAGALATFGY
                     QFITSKLALRKEEWIRVGQTRLSERMLGEQSLITLGQNVLHELAEYMDAQGGAIFVAD
                     GSRFHRVATHGVPEGTSLPDTFQAGDGLLGQALHAKRPLVVQDLPEGYFTVGSALGRS
                     APRHLLIAPFGVDGLTNTVVELAFFHPVHQSDRELIDRVAESIAVAMRSAHYRSRLQE
                     LLEETQRQAEELQVQSEELRVANEELEEQSRALKESHGRLEQQQAELEQTNSQLEEQA
                     QILETQKDELSEAALISNAQKQQLERVSQYKSEFLANMSHEMRTPLNSTLILAKLLAD
                     NPQGNLTADQVKSASTIESAGHDLLTLIDDVLDLAKVEAGRIDITPGDVSLQRLLDTL
                     HALFQPLAAQKQIQLRTTRAPGTPSSIQSDWQRLEQVLKNLLSNALKFTEAGQVSLDI
                     SMLPDGRLAFAVQDTGVGIPAAQQDLIFEPFCQGDGTTSRKYGGTGLGLSISREFVRL
                     LGGELHLTSTPGEGSTFTLILPQTLT"
     gene            complement(5845..10965)
                     /locus_tag="PK063_05000"
     CDS             complement(5845..10965)
                     /locus_tag="PK063_05000"
                     /inference="COORDINATES: protein motif:HMM:NF024583.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ96434.1"
                     /translation="MKATDMFSWLTGSEMGGRIRAFDWSRTPLGPIEQWPASLVSILG
                     VCLTAQTPMAIYWGADSWLLYNDAWRPVVGGKHPWALGHPAREVWPELWPTIQHYFHS
                     VLNTGEANWRTDELLPMQRFGYTEECYFDYSLNPIRGQSGAVEGILNIVQETTYRVLN
                     DRRTSLLRELASLSGSAQNDTDACARILQALATDSADVPFALLYQIDRDHREAQLAGS
                     IGLEDASLARQEQLDLTGNAAPGSWPLAAAIRNGGPLLLDELPDGFGLLPGGAWPEPT
                     RQCLLLPIGTATQDGGVVLVAGISPRRPLDEHYHHFFRMVSSHIAVAINNARAYQSEQ
                     RRAEALAELDRAKTAFFSNVSHELRTPLTLMLGPLEEELHLRPQSPALEVAHRNSLRL
                     LKLVNTLLDFSRIEAGRAEASYQPTDLAAYSADLASGFRSAIEKAGVTFVVDCPPLPE
                     AVYVDRSMWEKIVLNLLSNAFKHTFQGQITISMRHDAAGAELVVSDTGVGIPDEALPR
                     LFERFFRVQNRRSRTHEGSGIGLALVQEVVRLHGGSVQVESRLDEGSTFTVRISWGTA
                     HLPAEQIRAGDEPSVRSASAVAYVQEALHWLPDTQAIPPPASTSEAASAVIRPRVLVA
                     DDNADMRQYIERLLSRRYDVVTVGDGLAALNEIRRHPPDLLLSDIMMPQLDGIALLKA
                     LRADPAVHTLPVILLSARAGEESRVEGLEQGADDYLVKPFSAQELMARVTTHLDLSRI
                     RRKAEQEITRSKLFLERIAASTPDLLFVFDLLRTRTVYINHSLKSVLGYDVEQLAATQ
                     DNPIVTLVHPDDVPSVEQWLGRFDSAADAEVLEHKHRLRHADGTYRWILMRASVFDRS
                     PEGRARQIIGIAKDTTDQIRAEELMAASEARYRAIVSQATASVAQTDLTGRFVFVNQR
                     FCDILGYDQAELLDLHMQQITDPEDLPHCLERFQQLVNGGPDFVIEKRYRRKDGTAIW
                     MSVSVGGVREGQDLSHIVAVGLDITERKQQETRLLALSGRQQMLYELADAVNRAEPVA
                     SLYDIALEAMIRAVSADRASVLLFDQDGVMRFKAWRGLSDEYRKAVEGHSPWSADQRN
                     PPPLFIPDLATADLDPQLQATIRHEGVQALAFVPLTYGGQLLGKFMLYFDHPHRMSDE
                     DVGWTQTLARTLALGIERAKADDLLRSSEERLRLAMAAGRMGAWDLNLVTGETTWDER
                     QYELFGRSADCPIRQASDFYSAIHPDDVARVQEAARLGLETGVFSSEFRILTADGTIR
                     WLAGQGATVADEQGQVVRMVGINYDITERKRVEEDLQRSAAELERRVAERTIELTQSR
                     EHLRALATELNLAGQRERQHLATELHDYLAQLLALSRIRLAQAMQQPLSPPLAKTLNE
                     LQDVTNQALTYTRTLVAQLSPPILKEFGLPMALSWLAEQMLQRDLRVSLQLGPERLPL
                     PEDQAMLLFQSVRELLMNVVKHASVKEAFITVRVEEGCLQITVADRGTGFAESDHLAL
                     RKGGQVPGFGLFSIRERMLALGGRLEVHSQPGQGTEATLIAPLTPPSEQDRVPSASRR
                     AQIPHTVPSLGQSDDQEPINGRPLESARQIRVLIADDHAMVRQGLCGLLAGYGDIQVV
                     AEAANGSEALALARQWRPEVVLMDVNMPVMDGIEATRRIKDALPDTIVIGLSVQTIAH
                     VGHEMREAGAVAFLNKEAAVEDLYQTIQTARKELLSRS"
     gene            complement(11198..11665)
                     /locus_tag="PK063_05005"
     CDS             complement(11198..11665)
                     /locus_tag="PK063_05005"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96435.1"
                     /translation="MMLNTLMGSGLLTVVLLTGGQAVQQDVPAPVPNPGPGPTVPPKP
                     SDPIPTPPTVPKLLLQAWSGVERTSLFLIAEAAPRSQEAVSGKLLQLDLEKKEGRLGT
                     DLGREVPFRIPKPELFVHLSVGQRVTIKLDSGQQAVGVMETAAPELPSPSPAR"
     gene            complement(11688..>12092)
                     /locus_tag="PK063_05010"
     CDS             complement(11688..>12092)
                     /locus_tag="PK063_05010"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="four-helix bundle copper-binding protein"
                     /protein_id="HMZ96436.1"
                     /translation="MSTSIQSVDQHRLDCIQACLDCARICNTCGNDMIGMDMSEDEEA
                     QDLMVRCIRLCRDCADICLLAAQWMGRTSAFAVRLCAFCVEMCELCAGVCEQHAPHHA
                     MCGDCAKECRRCAELCHKMVLESVPASTGGTA"
     assembly_gap    12093..12192
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            12328..>13739
                     /locus_tag="PK063_05015"
     CDS             12328..>13739
                     /locus_tag="PK063_05015"
                     /inference="COORDINATES: protein motif:HMM:NF024491.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D-like domain-containing protein"
                     /protein_id="HMZ96437.1"
                     /translation="MMIVGWDIDTQVELVRETSASSEMPTKLGEFLVALLRRRRRLRV
                     SVLNWDYAVIYALERQWMPTAEPGWRRHRRLSYQVDDHHPVGASHHQKLVVIDDAVAF
                     VGGLDLSKSRWDTREHLSRDPRRVDADGVVYAPFHDVQMMVSGDAASALGDLARNRWF
                     NATGRRLSAPPPRSVEEVWPPRVNPDLTECPVAIMRTQPRYEELEEQREIEQAYLSAI
                     KRARRSIYIESQYFTAQAISHALAQRLSEHDGPDVVLVLRQHCDGWLERRTMDSLRAQ
                     LLHEVELADHYGRLRVYAPVVPGEAGAEPVAVHSKLLVVDDEFVCIGSANVSNRSMGF
                     DTECNLAVEACGQARVQSAIAAFRNGLLAEHLGVDPEVVANQIQTCGSLAAATDALRG
                     GGRTLADDCFEAMPPSDAMIPEHALVDPERPMAADHLLAGVGFRRERSRIVRRAMAGL
                     TLLAGMAILAAAWRWTALGQ"
     assembly_gap    13740..13839
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <13840..14235
                     /locus_tag="PK063_05020"
     CDS             <13840..14235
                     /locus_tag="PK063_05020"
                     /inference="COORDINATES: protein motif:HMM:NF020893.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HMZ96438.1"
                     /translation="LGSYRIRRLAGSRVEHLSRRMAERGLWAVLLVRILPIAPFSVIN
                     LIAGASSVSWRHFVLGTVVGMLPGIAIMATFVSGLEEAVREPSWQAFSMVGLVVAAAW
                     AGVWYVSSRLQSRQSTESVMAAGSSVPAT"
     gene            14261..15031
                     /locus_tag="PK063_05025"
     CDS             14261..15031
                     /locus_tag="PK063_05025"
                     /inference="COORDINATES: protein motif:HMM:NF015338.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HMZ96439.1"
                     /translation="MRVQVASYNIHRGVGRDGRYNPGRILRVLQEVNADIVALQEVDF
                     PGPHPHHFLTWLAAQLGMTAVGGPVRTSAAGTYGNALLTRYPVRNVRRWDLSVGRHEP
                     RGALAADMLCQGAMIHVVTTHLGLWPTERPRQATKLLEGLHVTEEELTILMGDLNEWQ
                     LWGKSLRVLRKVFGAPVSPPTFPTAWPLLALDRIWVSPPRALFEVHTHQSRQSRTASD
                     HLPVKAEIRFESVHGTGSVMREDYEPTPTSTGCGRSML"
     gene            complement(14983..15441)
                     /locus_tag="PK063_05030"
     CDS             complement(14983..15441)
                     /locus_tag="PK063_05030"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96440.1"
                     /translation="MKTEMKKFIPICCVCENVRGETLSPGTEPEWGPLKTYLDTHHLT
                     IGGYRLTHTYCPACAVQFTKLGRTARPAVTEEQPEIDNSVTPTILDAFDHMQQCDMDM
                     LVEACPTLTWNQVFSEVDRLSRMGQLRLSHLGYGRYSIERPQPVEVGVGS"
     gene            complement(15584..17224)
                     /locus_tag="PK063_05035"
     CDS             complement(15584..17224)
                     /locus_tag="PK063_05035"
                     /inference="COORDINATES: protein motif:HMM:NF017197.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF748 domain-containing protein"
                     /protein_id="HMZ96441.1"
                     /translation="MSIRIDSRQTTYTGESLHAASSVKKHHRGMWRWVMAACAAVILL
                     GGIGLWFVDEPLRVYAERQLNGRIAGYTFHIGTLDFHPIGLSVDLENVTVIQEAHPDP
                     PLAHIAEWHASIQWEGLLSGRLVSDHIIDRPLIHFTRPQAAQELQDAPAQKKSWQEAL
                     FAVYPLQINELSIKDGDVTYRENATSNPIRLTNIQVLAENIRNVRSKPLQYPSRVQVE
                     AMVAGGGHMKVDGHADFFAEPSMGVDVDITLQDINLADLLPLTAQRQIHLTQGSLTTS
                     GHVEFAPAAQEVRIASLNLHDVKVDFVHAARTKQREQRTAQQVSRTAAKAANHPTLLL
                     RIDQGKVERSEFGFVNQATNPSYRLFISGTELELENWSNQLSEGTARVQLKGMLMGTG
                     ATKITGAFRPEVESPDFDLSVKIVKTQVKSLNQLLRAYGGLDAAAGLFSLFSEVNVKN
                     GTVKGYLKPLFKDVTAYDPQQDRDKGMLNQLYEKTINALAEILKNTPRDEVATKTDLS
                     GTVENPQASTWELVLTLFQNAFFDAVLPGLEGKVQLER"
     gene            17577..18650
                     /locus_tag="PK063_05040"
     CDS             17577..18650
                     /locus_tag="PK063_05040"
                     /inference="COORDINATES: protein motif:HMM:TIGR00765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HMZ96442.1"
                     /translation="MAHTWKTLLQPQSLWKLLQEAFTAWSDDKIPRHGAALAYYTVLS
                     LVPLLIVMISLIGLIFGREAAQKHILDQTTNLMGPQSGDAVKQMIEHATQPTTGTIAM
                     LIGVATLLLGASGVFAQLQDSLNTIWRVEPKEGRGLWGLIRDRFISISAVLGTGFLLL
                     VSLVLSAALAAFGKWYSGWLPAPEVVLQLLEIVISLLVIAGLFALMFKVLPDARIAWN
                     DVWVGALLTAFLFTIGKFAIGLYLGKSDVGSAYGSAGSLVIMLVWVYYSAQIVLFGAE
                     FTQVYANELGSRIVPTENAVPADEPRAGRMRPAPTQPRLQAASGRQAQAASAQRQPAE
                     RLPWWGTVLLLWVAVTRFPRRSE"
     gene            18766..20847
                     /locus_tag="PK063_05045"
     CDS             18766..20847
                     /locus_tag="PK063_05045"
                     /EC_number="1.11.1.6"
                     /inference="COORDINATES: protein motif:HMM:NF012425.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004096 - catalase activity [Evidence
                     IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catalase"
                     /protein_id="HMZ96443.1"
                     /translation="MAGKQDMKTNQGHGGETHQQAGGPKEPVLTTDQGIPISDNQNSL
                     KSGARGPTLLEDFVLREKIFHFDHERIPERIVHARGSAAHGFFEVYESLSSLTSADLF
                     QRKGERTPVFVRFSTVVGGAGSVDTPRDVRGFAVKFYTKTGNWDLVGNNIPVFFIQDA
                     MKFPDLVHAVKMEADSGFPQAASAHDTFWDWASLMPESTHMLMWAMSDRTLPRSFRMM
                     EGFGVHTFKLVNDKGKETFVKFHWKPKLGLQSTVWEETLKLQAADNDYHRRDLREAID
                     AGNFPEWELGIQTFDQAFADKQPYDVLDATKLIPEEQIPVRRIGRLVLDRNPDNHFAE
                     NEQVAFCPANIVPGIDFSNDPLLQGRLFSYLDTQKSRLGTANFHQLPINAPKCPMANF
                     QRDGQMQMRVPTGRANYEPNSLAAHGEEGGPRESPQGFTTAPGRDDREEQGDKLRVRP
                     ELFADHYSQARMFWKSLTDNEQAHLASAFVFELAKVNLDEVQSRMVGRLRNVDEGLAK
                     RIADGLGMPLPGKIRAAREPIEMKPSPALSIQKNMLATLKGRKVGLLYAEGSNGGDID
                     RMIKQVEKAGGTVFLVAPKLHGTKLENGKELKADGQLAASPSQLFDAVAIILSAKGAQ
                     MLLKEGAAIQFVMDAFGHLKAIGHSEAAQPLLDKAGVVPDEGVTDLRGSFVEAAAKRF
                     FAREPSVRTLA"
     gene            complement(20962..21399)
                     /locus_tag="PK063_05050"
     CDS             complement(20962..21399)
                     /locus_tag="PK063_05050"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96444.1"
                     /translation="MKTLMHSLLALALVSLAACSSSPTASKTRSEMDVGTKTGMVKNI
                     VIKDTLTPDALTVRAGDEVRWINQRQDSVTVTIDGPLEHNVSCRNGFSKALGMGVDNS
                     TTLASNETAGLCFSRVGTVNYSVRPSSDTRTTMADTKGSITVQ"
     gene            21606..22487
                     /locus_tag="PK063_05055"
     CDS             21606..22487
                     /locus_tag="PK063_05055"
                     /inference="COORDINATES: protein motif:HMM:NF039714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6279 family lipoprotein"
                     /protein_id="HMZ96445.1"
                     /translation="MSPSEIIRKSGGSAFHRLTGLLLTLVLLLSGCALSFGYRHADWL
                     ITRQLDHYLDLTSSQRRIVNARLQPLLWRHRIEALPQYEQFLKDLHARIGRGLTSEDV
                     EWTFASYDRFRADLFERAIPEGTQLAMLLKNNQITYLERVFRKEEVQAESLARRSVST
                     RLDERARKGIATAEEWLGPLSHEQSVQLREMMLALPDSQPTWWQYRRQRHGEVLAMLR
                     TSTSADQIAERLRYLFVQSDQTAPTGYLKMMTEMRAALTRMVLDVDRMLTPAQRRHVL
                     VAIQKVIDEVHALAHNS"
     gene            complement(22769..>23596)
                     /locus_tag="PK063_05060"
     CDS             complement(22769..>23596)
                     /locus_tag="PK063_05060"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96446.1"
                     /translation="TAQNGPSLTEILTALANPQTHVVVNLVGLPLHDRPAFFFGLLHK
                     ILELRAASGRPHWILIDETHHLLPRDGNPGAPGLTQDCTGMMYVTVHPDQIDPAILKT
                     VDLVFALGQSPGKTIEAFCQARGQQAPTLPSTELEAGQTLMWDPTLAVAPEVLEIAPS
                     STERRRHRRKYAEGELPPDRSFYFRGPAGKLNLRAQNLLLFMQLGEGVDEQTWQYHLN
                     AHDYSTWISDMIKDETLSKVVHDIEARPELSAEESRRLIRAAIEEQYTVPATGIEPA"
     assembly_gap    23597..23696
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<23697..24178)
                     /locus_tag="PK063_05065"
     CDS             complement(<23697..24178)
                     /locus_tag="PK063_05065"
                     /inference="COORDINATES: protein motif:HMM:TIGR01484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIB family hydrolase"
                     /protein_id="HMZ96447.1"
                     /translation="MRYMALAADYDGTLASDGAVYPETVAALERLVASGRKLILVTGR
                     ILPELLDIFPQISLCELVVAENGGVLYRPATKEVTLLADAPRPAFLEEVQRRAVQHLS
                     LGHVIVATRVPYETVILDIIRDLGLELRIIFNKGAVMVLPHGINKATGLTAALARLEL
                     S"
     gene            24325..25305
                     /locus_tag="PK063_05070"
     CDS             24325..25305
                     /locus_tag="PK063_05070"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96448.1"
                     /translation="MSYSGRIHLIAGWCGLVLIVGGCTTVLPPADHGAANESSQRCVP
                     AMTKRARVAAAGDETPVTPTTEARSRFSSDALQVAEVVGVLPLVNHLASDTGSSRRDP
                     LASVVLRQRLTEILLLTLFEITSTTAELTCERDRADQVADRIDEIDGARVKRLTIASI
                     LFGGIASIVSGGIGLAAGASVGGEAADVAGGALASWFGVSALFTHSEVEFRHERNVLQ
                     EIWEDPSQPRLFSPTIWRYLHRAHDEKGKLPREQVLDSWQQAGRMGENGSPSEQERRR
                     LFFGAGGRYGAAELHARASMLETLEASIRLLYEELEVLMRELAEETADVS"
     gene            25328..25768
                     /locus_tag="PK063_05075"
     CDS             25328..25768
                     /locus_tag="PK063_05075"
                     /inference="COORDINATES: protein motif:HMM:NF016045.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low affinity iron permease family protein"
                     /protein_id="HMZ96449.1"
                     /translation="MVSKHTKTRDSGLFVRFANEASRVVGSAGAFGVAIVVVLLWSLS
                     GPLFGYSDTWQLVINTGTTIVTFLMVFLIQNTQNRDSAATQLKLDELIRSTQGAHNAL
                     LDLEKLSSKDLEDIRMLYQKLADRARREKKGGWEDTDTPELKRV"
     gene            complement(25775..>27112)
                     /locus_tag="PK063_05080"
     CDS             complement(25775..>27112)
                     /locus_tag="PK063_05080"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013434.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HMZ96450.1"
                     /translation="HLSNAIDSGYLDIERLHGRSGARLAAESHTAAIDWIEKTIKDAR
                     IDCDFLRVDGYLCAASPDDAQHIKDEWMAVLRAGLSEVEHVTRPAGPLAKNGPCLRYP
                     HQGQFHPLKYLAGLVKALQSGGCRAFSGAHVTKVESGKQARVETSQGCVVTADAVVVA
                     TNTPINNMVAIHTKQAAYITYVIGAPIPAEAIEQALWWDIQDPYHYVRTQRHSFPDGR
                     EELLLIVGGEDHKAGQADDAERRYGRLETWAREYFPAMGAVSYRWSGQVMETVDGLAF
                     IGKNPGDVDNIYIATGDCGMGMTHGTIAGLLLTDLIMGRECPWASLYNPSRQPVKAMG
                     EFVRESLNVVAQYTDWVTKGDVEREEDIANDQGAVLRDGLTKIAAYRDADGTLHTCSA
                     VCTHLNCIVSWNHSEHTWDCPCHGSRFDRFGKVLNGPAITDLAPVKRKERTPT"
     assembly_gap    27113..27212
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            27413..28273
                     /locus_tag="PK063_05085"
     CDS             27413..28273
                     /locus_tag="PK063_05085"
                     /inference="COORDINATES: protein motif:HMM:TIGR02772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0045027 - DNA end binding [Evidence IEA];
                     GO_process: GO:0006303 - double-strand break repair via
                     nonhomologous end joining [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Ku protein"
                     /protein_id="HMZ96451.1"
                     /translation="MPRSLWKGSISFGLVNIPVVLYSAENRNSFDLTLLDRRDMKPVG
                     FKRYNKESGKEVTWDQIVKGYEYDKNRYVVLTDEDFKRANVEATQTIDIVNFVRAEEI
                     APTSFETPYYLAPDKHGEKGYALLRETLKKTGKAAIATVVIRTRQYIAALIPWSEMMV
                     LNTLRYANEIRSSKELDLPAKHEKSAQVTPREVDMAMKLVEEMSEPWKPERYKDTYHE
                     DLMRLIEKRIKAGKTEVVTTPGKEEGGEKPGRAKVVDLMALLKRSVQQSGHSKHPARE
                     KERSPRRKSA"
     assembly_gap    28309..28408
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <28409..30112
                     /gene="treZ"
                     /locus_tag="PK063_05090"
     CDS             <28409..30112
                     /gene="treZ"
                     /locus_tag="PK063_05090"
                     /inference="COORDINATES: protein motif:HMM:TIGR02402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malto-oligosyltrehalose trehalohydrolase"
                     /protein_id="HMZ96452.1"
                     /translation="YPDPCSRFQPEGPHGPSLIVDPGAYTWHDDRWPGVAMHGQVIYE
                     LHIGTFTPEGTFEAAIERLDGLKEIGITVIEVMPVAEFPGRWNWGYDGVGLYASAHVY
                     GDANSFKRFVDEAHRRGLGVILDVVYNHLGPDGNYLPTFSAEYFTDRYPNEWGQAINF
                     DGPGSGPVRDFFIQNACYWIREYHVDGLRLDAVHAFHDASPVHVVAELSRAARQAAGP
                     RSIILVAECEAQWVQTIQPLAEGGWGLDGVWSEDFHHTVRVAATGRSEGYYNDYRGTP
                     QEFISCVKRAFLYQGQRYQWQGKPRGTVVSEEPAEGFVFFLQNHDQIANQLWGDRLHQ
                     KVSPSVYRALTALLLLAPETPLLFMGQEFAASSPFLFFTDFPPGQLANDIHQGRKQFL
                     SQFPSYASSAAQDAIGDPSAPAMFERSKLDWTERERHAGIVALHRDLLRLRREDDVIA
                     QQRRDRVDGAVIGPSAFLLRYAGQHGDNRLLLVNLGPDLDFRPAPEPLLAPPSGRMWT
                     FRWSSDAPSYGGPGVIEPLTETGWKIPGGAAFLYAALDDTSKDTGKTPAMASPHEEES
                     R"
     gene            30109..>31688
                     /locus_tag="PK063_05095"
     CDS             30109..>31688
                     /locus_tag="PK063_05095"
                     /inference="COORDINATES: protein motif:HMM:NF017964.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amylo-alpha-1,6-glucosidase"
                     /protein_id="HMZ96453.1"
                     /translation="MTTMADAMVLTVPPERLRDPNAFLAREWLVTNGLGGYASQSLLC
                     APTRRYHGLFVPDLPAPWGRTVMMPRFDDEVLVDGDAVFLSGVEFSDGRLESNLLSVF
                     DGFSRERQTPVWRIRVKGRRLEKRVIMPYGHNSVYVEYRLLEGDPVGLRLRPFVTFRM
                     LDARLHDAKRPPFPLTVLNGRYDMHLCEGAPSLKLCLRPHGGKFVADYELSVDVSYRV
                     DRDRGSEHIESLASPGYFVADLTQDRPLAFVASTEPWELLEFDPEAIFEAEAKRLGKL
                     LSQRAGEADDDIEGWLTMAADQFVVAPGSRLEEQALARASGNEARTIIAGYHWFTDWG
                     RDTMISLEGLTLCTGRHQEARAILRTFANYVKDGLIPNLFPEGERMGLYHTADATLWY
                     FHAISRYYRVTNDRETLLTLLPVLRSVLEHHVRGTHFGIGVDAKDGLLRASAEGYQLT
                     WMDALVDGWVVTPRRGKPVEIQALWYNALRCMEEWEVLAGQTPSRWRDLAEQVQRSFN
                     ERFWIAAEGYLYDVIDGER"
     assembly_gap    31689..31788
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            31951..32673
                     /locus_tag="PK063_05100"
     CDS             31951..32673
                     /locus_tag="PK063_05100"
                     /inference="COORDINATES: protein motif:HMM:NF014017.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HMZ96454.1"
                     /translation="MARIGTSGWHYAHWRGPYYPPSVPPRAMLDYYARDLDTVEINNS
                     FYRLPPSGTFEGWKKSTPPGFCFAVKASRYLTHQKKLLDPSPALKRLLGAAVHLGAKL
                     GPILFQLPPHWRCNLERLSDFLRTLPPSHRYSLECRNATWHTGEVYRLLEQHNVAFCL
                     FELGGCMTPIEVTADFVYVRLHGPGNKYQGDYPTATLKAWCRRIRQWTRCDKDVYVYF
                     DNDQAGYAIKNAMSLRAMVDGS"
     gene            complement(32722..>34169)
                     /locus_tag="PK063_05105"
     CDS             complement(32722..>34169)
                     /locus_tag="PK063_05105"
                     /EC_number="1.10.3.-"
                     /inference="COORDINATES: protein motif:HMM:NF013791.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0070069 - cytochrome complex [Evidence
                     IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_process: GO:0019646 - aerobic electron transport chain
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="HMZ96455.1"
                     /translation="TGHRPRHNFASGRIAASGTHGRSAPLMEMEALQIPMLYGRVAIA
                     VAALAHALCATFIVGSSVIGSATETIGHVTQNLRFERLSRLIAFTLILTTAGISFLGV
                     TFVFLLNIFWPRFWSQLFHIMFWPLLLEASFFLAEAIFAYTWYYSWDWANQQPARKRW
                     HLVFGWSAAASSLIAMLMIDMVASYMLTPRPPDDTWAKLFNPTMLYLDTHRIVGNLTW
                     TGFGLAGLCAAGFLRSGGEDDRAFYRWAGGVCFIIGFGALLIMPAIGYQYLLRVRHIE
                     PQAFYTLMLGARSWLFDLVATLYSLLVLFGSWYIWRSVRAQPANDEGGTARLALPMSL
                     LIVAIAGMILSQPYQLQHIPGMQILTDRLINPLGKMQPNKYFALAFLVVFGLMNWLFF
                     FRSYANRVPWWQGQSGSEKESSSPALLITLALCAMLMMLTMGWARETARAYNGYLIYG
                     QVRLEDERSTYEGMKTNPGTPDAATRRPVSP"
     assembly_gap    34170..34269
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<34270..35461)
                     /locus_tag="PK063_05110"
     CDS             complement(<34270..35461)
                     /locus_tag="PK063_05110"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96456.1"
                     /translation="MINYGTVLPAIQIPLLGNSVAVGLFSLLHIVPAALSVAFMLMAP
                     VFEFRGRTDPFDRELALLVTRVTVVVFSVSTVLAVIMVELMIGLFPVTTMWMWNHFRV
                     PILFGVASFMLMLLALYPYYHFWDRLRATSITLHMVLGALAAFFMLPWVFMLDGMGAF
                     MLTPVQEGGTWERLFTPTWLPLVIHRMVGNLMIAGYTLAAYGAWRVWSPGEPALKPYY
                     QHLLSRGWVIGLVAFLLQPFTGLLYAMAIHRAAPDAQASIMTGPYVPWLYLQLLLLSL
                     FFLGNDVLTKRMRTLTGNRQRWLDIGFPVLAALLLLSAGYPELRRVCVYLLVGVTVWR
                     VAASVSKAPTESALSPSPVRSLAVGLALLSFLLYLTMGVMREASRRPDTVRGIISLQD
                     ELRHQ"
     gene            complement(35454..36488)
                     /locus_tag="PK063_05115"
     CDS             complement(35454..36488)
                     /locus_tag="PK063_05115"
                     /inference="COORDINATES: protein motif:HMM:NF023249.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3341 domain-containing protein"
                     /protein_id="HMZ96457.1"
                     /translation="MSRTQPCEGLIALFPLDADLDSVRLSLEGSGISQDQIALLTPVP
                     LKSASATDGTSQPLWPYIITIVAGLVGIGVGVFFAAGTALLYPLMTGGKPIVSAPIVG
                     IISYETMMLLAIVVTFITMIVRIRRARRASVDRETRIDDGKIALSVRLVEDGQEQRVK
                     TLLEMAGAEDVRLVTHPSPIQQGMQRAHVTAAWLLICITVGGCSPDMQEQPSYRSQEA
                     PRLHSPTGSVPRDSRAILSREARTMELEGGRAPELYRINCLPCHGEGGEGTGLVAPYL
                     HELPANLRSPRVRALSKTELYRIITQGKDMMPSFQGELSATERMILASFVHAMEPDTT
                     MAHEERRSHD"
     gene            complement(36439..37800)
                     /gene="nrfD"
                     /locus_tag="PK063_05120"
     CDS             complement(36439..37800)
                     /gene="nrfD"
                     /locus_tag="PK063_05120"
                     /inference="COORDINATES: protein motif:HMM:NF015851.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysulfide reductase NrfD"
                     /protein_id="HMZ96458.1"
                     /translation="MNHSTAGWEEMPAINRDLLAPLSAGGRGYVLLVTLLAAMVSAGI
                     GAWVYQIETGIGRTNLHPPIFWSAYIASFVYWIGVSHSGTFISGVLRLTKAEWRRPIT
                     RVAELMTIISVVIATLFVFYHLGRSWRWYYLIPYPNQREIWPDFRSPLMWDATAVFTY
                     ATASTIYLYLPLIPDFALVRDRIGGWRKPLYSLLSLGWRGSQREWTALNTAIRIITPL
                     IVMVMISVHSIVGWDFGMSLVPGWHTSIIAPYFVVGAVHSGLGMVVIGLYLVRRIYRL
                     DAYIRLEHFDKLGKLMIVMTLTLAYLYFADQLTVWYGAIPDHLSVMHAVMSGPYAVPQ
                     WTMITLIYVLPLITLTIPAFRTWPAGMLVIGLCINIGMYIERMLILTPPLAHPRLTYN
                     WSDYFPSWVELTIMAGSLSLAVLLYVLAIKFVPIISIWEEKEGRLHEQDSALRRPDRT
                     LSA"
     gene            complement(37797..38519)
                     /locus_tag="PK063_05125"
     CDS             complement(37797..38519)
                     /locus_tag="PK063_05125"
                     /inference="COORDINATES: protein motif:HMM:NF024247.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HMZ96459.1"
                     /translation="MEDKQRPSDEPRPYRWQMVIDLDRCTGCEACVVACHAENNIRIS
                     GPGEASDGRAINWIRIERYWEGAYPDVKARFMPVLCQHCADAPCEPVCPVYASYHTPE
                     GLNAQVYNRCIGVRYCGNNCPYTARQFNWFDPHWDPPLEQQLNPDVTVRQNGIMEKCT
                     FCVQRIRQGKEQAERDGRPVRDGDITPACAQSCPTTALVFGDGNDPTSRVATMAKSGR
                     GFHLLESLGTHPAITYLKRLDE"
     gene            complement(38572..40788)
                     /locus_tag="PK063_05130"
     CDS             complement(38572..40788)
                     /locus_tag="PK063_05130"
                     /inference="COORDINATES: protein motif:HMM:NF012602.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HMZ96460.1"
                     /translation="MDVKRRTFIKALGLTAAGTLLPGCDQEVRRLVPYVLPDDEIIPG
                     VAEWYASTCGECDAGCGIIVKVMEGRAKKIEGNPLHPVNQGKLCAQGQAALQRLYNPD
                     RLRGPLRRMGTEADQRFTPVSWDEGLHQLADQIRHAKGPVIMISRPLSGTLADVVSDF
                     VASVKGSLYFYDPSPELALRAAMKQAFDIHDLPAYDLGDADYVLSFGAPFLEQWLSPV
                     SFGIAFGRMRQGRKNRRGRFVHVEPRLSLTAASADRWLPIRPGMEGLLARGIGHILLS
                     EHRSSLPTGRLHAYESLYGRLSLDEVAKQTDISTADIKRVARAFAEADSPQAIGGGTA
                     CAHTNAFETHLAIHGLNALAGNINKAGGIRWYQSASLTLHPEIPWLSERRIKELAETI
                     EKTGQRPLLLLYDCNPLFSVPPAIPIRRLFDRASYIASFSGSLDESTVSADLILPDHH
                     RLETWGDHVQGGSSPYRAASLVQPVVVPLYDTRGLGDTLLELTRQLAGKHAGVESFPE
                     HIKKRWQHFHTSHSSGSHEPFQSVWEQLLQQGGWWDSAANEQRLQQSSSAVEYRPPEF
                     DGDASEFPFYLYPFAAPHLGQGRGANLPWLQELPDTMTSAVWGSWIEINPATAQAMGI
                     QQGALVRLHSRHGSLEAPALHYPGLRPDVIAMPIGQGHTDYGRYAARRGANPMTILAP
                     LFDKQSGALAIGATRVRAEPLNVPGTLILLEKPGTTAAGSSDLISIERPPSSKART"
     gene            complement(40829..41347)
                     /locus_tag="PK063_05135"
     CDS             complement(40829..41347)
                     /locus_tag="PK063_05135"
                     /inference="COORDINATES: protein motif:HMM:NF025875.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c3 family protein"
                     /protein_id="HMZ96461.1"
                     /translation="MTRSLWQSLGLVSLATVSALAIGILYSKGSADSAAHDQQPIAFN
                     HAFHAGELALDCRYCHRAAHISPAAGIPSLQLCMGCHQNLDVATAGIQTLVDHWKRQA
                     PVEWVRLQRLPDFVYFTHERHLAQGLECTTCHGDVTRMTSTPRAATYEMGWCLSCHQQ
                     RGASRDCVTCHK"
     gene            41628..42749
                     /locus_tag="PK063_05140"
     CDS             41628..42749
                     /locus_tag="PK063_05140"
                     /inference="COORDINATES: protein motif:HMM:NF024771.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enolase C-terminal domain-like protein"
                     /protein_id="HMZ96462.1"
                     /translation="MERDVCSTNGDSGPKIEKVQVSAYTIPTAGPESDGTLEWDRTTL
                     VLVDVSAGGQHGIGYTYADVSTAWFVKQNLAPVVEGRDAMHIADAWWAMMRSVRNLGH
                     PGVASMAIAAVDTALWDVKARLLDLPLVSLLGRVRTAVPVYGSGGFTSYSIDRLEEQL
                     GGWVRDGISRVKMKVGRQPDQDLRRVEAVRKTIGEEAQLFVDANGGYGRKQALQLSEG
                     FAKAGVVWFEEPVSSDDTEGLRLLRDRVPAPIQVTAGEYGYDLFYFRRLLDAEAVDVL
                     QADASRCGGITGFLKVGSLCEARPVPLSAHCAPSLHVHPGCASMSVCHIEYFYDHVRI
                     EQLLLDGAIRPVGGALYPDLSRPGIGLDFKYQDARRYQV"
     gene            42751..45759
                     /locus_tag="PK063_05145"
     CDS             42751..45759
                     /locus_tag="PK063_05145"
                     /inference="COORDINATES: protein motif:HMM:NF014910.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-linked oxidase C-terminal domain-containing
                     protein"
                     /protein_id="HMZ96463.1"
                     /translation="MREPLIHIQSAGQDSTQGASYAAEPSDAMREHLARRIDAQGLAE
                     ALRKNIDGEVRFDEGSRALYATDASNYRQVPIGVVIPRHADDVLRTIATARTYDAPIL
                     ARGGGTSLAGQCCNYAVVLDCSKYMHRLVGIDVAGRSARVQPGLVLDDLRHAAEQHHL
                     TFGPDPSTHNHCTLGGMIGNNSCGVHSVMAGETSENVIEMDVATYDGLRLRVGRTSDH
                     QLDEIIAHGGREADLYRRLIALRDRYADLIRSRFPNIPRRVSGYNLPALLPEHGFDVA
                     KALVGSESTCVTVLEATVRLVSSPRVRSLLVLGYPDVYAAGDHIPDILRAKPIGLEGM
                     DDRLVEDMTKMKIHPDDVKLLPEGRGWLLAEFGGESKDEADGQAHRCMELLKAAGHPP
                     SMKLFDRRRDEQVIWTVRESGLGATAHVPGEQVTWEGWEDSAVPVERLGDYLRALRRL
                     FEKYRYACALYGHFGQGCVHTRIDFDLQTQEGISRFRSFLFEAADLVKSFGGSLSGEH
                     GDGQSRAELLPRMFGPELIGAFEEFKAIWDPDGKMNPGKIVRPFRVDENLRLGSDYHP
                     PDPQTDFTFPQDEYSFSRATLRCVGVGECRRQAGGTMCPSYRATREELHSTRGRARLL
                     FEMLEGDPLTRGWRNDTVKEALSLCLACKGCKGDCPVHVDMATYKAEFLAHYYKGRLR
                     PRSAYSMGLIHRWARWASRAPGMANFITQTPGLCDVVKMLGGISPHRRMPRFAAETFQ
                     AWHRQRAKRAGGGQPVLLWPDTFNNYFYPETARAATEVLEAAGCAVFVPQTNLCCGRP
                     LYDFGMLRQAKRHLQQILCELASTIRSGMPLVVLEPSCAAVFRDELGNLFPHDEDARR
                     LAKQTFTLAEFIDKRLPDWELPQSHQSVTVHGHCHQKAVIGLGAEERVLDRLGLNVQM
                     LDTGCCGMAGSFGFKQEHYDISMQIGELALLPAIRNTATDTIVISDGFSCRQQIEQST
                     HRQGMHLAEVIHQAMGNVTMHVSASAHGGT"
     assembly_gap    45810..45909
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <45910..46596
                     /locus_tag="PK063_05150"
     CDS             <45910..46596
                     /locus_tag="PK063_05150"
                     /inference="COORDINATES: protein motif:HMM:NF024895.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HMZ96464.1"
                     /translation="LNHESGAVPIQSGSDCSMTSSKTLIAVVLICLIGTGMLNSRPVL
                     GEWYVAGQFGANFADQLSDIHGTGNLSGFRAPDFDLQNSLLYGAKVGNFPGNGWFGLE
                     LDVFHSTPHVKNLDDVPGFHMRVTNVGVNLLARYPGVTFQPYAGIGAGVAIARIGDSA
                     TTRGSTDASSALNLLVGIRAFVTPYVALFTEYKYSQSTFEFSHAFGPSSGFNGNYDAH
                     ILVTGLSYHF"
     gene            46553..47293
                     /locus_tag="PK063_05155"
     CDS             46553..47293
                     /locus_tag="PK063_05155"
                     /inference="COORDINATES: protein motif:HMM:NF015782.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Slp family lipoprotein"
                     /protein_id="HMZ96465.1"
                     /translation="MMPTSWLPACHTIFKKRYWATAALFLSAWLLSGCAQSAHQSGRD
                     LLDQILPDQLQQQIDPTVTFPELKANPSAYQGKTIMVSGIVVKSKRRKDQTEIEVLQI
                     PTGTGAVPSKDRAHSQGRFLAVKSGEFLDPAVVDAGTPVTVVGEVGPPVTRPMDDGEY
                     TYPVLAITHLVDWDEVNPAMRSAPYAYPYGRSMYAYPYAYWGPGGWYGGYPGYGYGYP
                     YYGFYGFGGGSSAPAGPPPADAPPQFNK"
     gene            47327..49942
                     /gene="ligD"
                     /locus_tag="PK063_05160"
     CDS             47327..49942
                     /gene="ligD"
                     /locus_tag="PK063_05160"
                     /EC_number="6.5.1.1"
                     /inference="COORDINATES: protein motif:HMM:NF004628.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006303 - double-strand break repair via
                     nonhomologous end joining [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA ligase D"
                     /protein_id="HMZ96466.1"
                     /translation="MSLRQYWKKRNFRNTPEPRGKETPAGARLQFVIQQHAASRLHYD
                     FRLELDGTLKSWAVPKGPSLDPAQKRLAVHVEDHPLDYASFEGIIPEKQYGAGTVLLW
                     DRGYWEPIGDPKADYRRGRLKFTLHGVKLQGIWNLVRMGGREEAGKENWLLIKEKDAE
                     AKRGTQSRVTDRLTSSVASGRSMEQIATGEHAVWHSNRSSTTSAKKRAVSRPVEKTPA
                     AGARKAAQEEWIVPQLATLVTASPEGEDWVHELKYDGYRILCRLKDGQVRLLTRNGHD
                     WTAKLPHIAAALTDLPAQAAWFDGEVVALSPDGRISFQLLQNAFDAHSDSDLLYYVFD
                     LLYLNGYDLREVPLLERKRLLSALLKDRPSSSLIQYSDHITGRGDVAFAEACRSGMEG
                     LIAKRADAPYLSGRNRNWVKVKCGQRQEFVIGGFTDPSGSRSAFGALLLGVYDAQGRL
                     QFSGRTGTGFTERSLKELHTRLKKIEQKQPAFVNPPVGSEARGVHWVKPLLVAEVAFA
                     EWTNEGQLRQASFQGVREDKDARSIIHERPDSGPSSPKARKGRGHARSRRISSNQQTP
                     SAGAEADETAPVIGGVTLSHPDRVLFPEQGITKIALARYYESISDWILPHVEGRPLTL
                     VRCPEGHKKECFYQKHAGEHIPDTVGRVEIPEEKGSSWYMVADDLPALIGLVQMGILE
                     LHTWGAKRDQLERPDRMILDLDPDPAVEWPLVIEGAQLLRTLLEELDLVSFVKTTGGK
                     GLHVVVPLQRAHTWDEVKTFSKAVADHLVRAIPERFLANMSKQKRKGKIYVDYLRNAR
                     GATAVAAYSTRARPRAPVSVPLAWNELSTDLRSDHFTVDNIAERLEHLRQDPWKTYFT
                     TRQRITKNMVRRLAG"
     gene            50090..50359
                     /locus_tag="PK063_05165"
     CDS             50090..50359
                     /locus_tag="PK063_05165"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96467.1"
                     /translation="MNATTTRTLPLTGKTRSTPAVSQHDTCRCLRCGGFLVDERCMDI
                     GESLGGYWFMAMRCVQCGDITDEVILRNRSAQLATTTQHEVVRAA"
     gene            complement(50449..50820)
                     /locus_tag="PK063_05170"
     CDS             complement(50449..50820)
                     /locus_tag="PK063_05170"
                     /inference="COORDINATES: protein motif:HMM:NF018767.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensory rhodopsin transducer"
                     /protein_id="HMZ96468.1"
                     /translation="MEPIGRRRWVIAEGYIPSKSHGPEPQMTSHETMCILNSSDQDAT
                     VQVTIFYADREPVGPYIIQVPARRTKHVRFNDLTDPAPIPLDTDFSSLIDSNVRIVVQ
                     HTRLDSRQAENALFSTMAFPV"
     gene            complement(50858..52609)
                     /locus_tag="PK063_05175"
     CDS             complement(50858..52609)
                     /locus_tag="PK063_05175"
                     /inference="COORDINATES: protein motif:HMM:NF014795.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-binding protein"
                     /protein_id="HMZ96469.1"
                     /translation="MATTVADLLVERLIQWGVDTIFSLPGDGINGIYEALRTRQDKIR
                     VVLVRHEESAAFAACGYAKFTRRLGVCLATSGPGGIHLLNGLYDAKCDGQPVLAITGH
                     TYHDLIGTHYQQDVDLERLCSDVAAYSQRVMSPAHVGNVVDEAIKTAISRRTVAHITI
                     PKDIQDWSVEDRGSKANIPGHSGDLYSDPLPLPSRSLLEKAATLINAGSKIAILAGRG
                     CLGARAEVLQLAELLGAPIVKPLLGKAVVPDDHPLTTGGIGLLGTAPSQEVLEACDTL
                     IIAGTSFPYLEFYPKPGQARAVQIDLDAARIGLRYPIEVGLVGHCWDVLRALLPLLEK
                     KSDRSFLNTAQASMQQWNELMEERGTRTDTPLKPQVVVRGLNEFLADDAIICCDTGTV
                     TTWAARHIIIRENMEFSASGTLASMGNGLPYSLGAGIAYPGRQIVCLAGDGGCTMLMG
                     ELATLVRYGLPVKIIVLKNNLLGMIKWEQLAFEGNPQYGVDLQPIDFALFAKACGATG
                     LTVDDPGDVREVLREAFAVQGPAVVQAVIDPLEPPLPGKITTTQAWQFAKALAKGQDD
                     RWGIIKTLVESKIREVV"
     gene            complement(52628..53809)
                     /locus_tag="PK063_05180"
     CDS             complement(52628..53809)
                     /locus_tag="PK063_05180"
                     /inference="COORDINATES: protein motif:HMM:NF013740.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HMZ96470.1"
                     /translation="MKPGYVETLAEERPRVQTSKERGTSVANRHLWEITPVRDLLWLG
                     GILFLLWFGYYLRGVFTPVLVALLLAYLVNPLVRRAETAWHIPRPVTVSIVLLLSAMM
                     LGGLVTWLGPLLAEQVQSFAERVPGYLQSIATQYHVTLGNFSEPLSSIATSLRDDPLS
                     ILKPIFSGTGQAFGVLGSVIGTTADVTLALVLIPIYFFFFAWQFDSALAQLRRYIPPG
                     YRPRARHIVRRMDQAVSGFFRGRLTIALASAVLYSVGWALTGIRYWFILGLITGILTI
                     IPYASLIGWPLAVLLKYLDGFSAGAGSFDVMTVVVWPSVAYLVVQFIESWLLTPWVQS
                     QSMEMNAVTVLIVVFIGGALGGFYGLLLAIPIAACLKILVQELVLPRLEHNAASPPPS
                     F"
     gene            complement(53852..54766)
                     /locus_tag="PK063_05185"
     CDS             complement(53852..54766)
                     /locus_tag="PK063_05185"
                     /inference="COORDINATES: protein motif:HMM:TIGR00765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HMZ96471.1"
                     /translation="MSASLTSASPRWNPWKLGGLGWKELGQRLWTDSQKDEILGRAAQ
                     LAYYFLLALFPALLFLTALLGLFPLEQVLPELMTYLRTVLPADALSLLQKYLDSVVKG
                     SGSDILSLGLLGALWASSSGVTAIMESLNVVYGAQETRPYWKVRLVAALLTIGLAAFI
                     IISITLVLYGERIGEWIADLIGLGWLFLLTWNVLQWPVAIGLMLLALAIIYAVCPDVD
                     HDWRWVTPGSVVAVLLWMGLSLGFKAYVDHFGNYNAAYGSIAGVIVLMLWLYLTGVVI
                     LLGGEINAQIERAALALRSFSEQSSHTA"
     gene            complement(54782..55441)
                     /locus_tag="PK063_05190"
     CDS             complement(54782..55441)
                     /locus_tag="PK063_05190"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96472.1"
                     /translation="MDIAEKLELLEQRIKDTAEGATMKFSRLLDEGSQSVTQMVDKTK
                     AALDPIHKVDDYPWLMLGGAICAGYAIGLLEARTRAQRGVYPYYPPGAHASQVMPESE
                     TEGKTASRRAEGIYDYYPDPTHRARRTEQRSHSTIWETMSRELEIDTEQAKAALMQAG
                     RTLMVEFANKLIPEIARSLGVTLTSQGKQSRPSYDQASYSETEGRGNARSSAGSASQF
                     R"
     gene            complement(55462..55869)
                     /locus_tag="PK063_05195"
     CDS             complement(55462..55869)
                     /locus_tag="PK063_05195"
                     /inference="COORDINATES: protein motif:HMM:NF018980.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HMZ96473.1"
                     /translation="MENPHPISIASLVTGLVEDLRRLFAQEVQLARHEMQHELGKVVK
                     SAMHAGIAMMLAFLAVLFLLMTLIHLLHFYSGLPLWACYGIVALVAAAAGAAFFARLI
                     AIGTTLRLWPFRTFYSLKEDAKWIKEQLLSTKT"
     gene            complement(55888..56238)
                     /locus_tag="PK063_05200"
     CDS             complement(55888..56238)
                     /locus_tag="PK063_05200"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96474.1"
                     /translation="MEQDMKHMADRAKQAGSSIQDAIHDTATSAEHMAKRAGDAVESA
                     ADHLRDRLPKDSAAGEAADTVVRKVKETSVYLQEQGIGGVVEDLEILIRRYPLQTLLL
                     GLGCGYLLSRARTD"
     gene            complement(56372..57475)
                     /locus_tag="PK063_05205"
     CDS             complement(56372..57475)
                     /locus_tag="PK063_05205"
                     /inference="COORDINATES: protein motif:HMM:NF014893.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HMZ96475.1"
                     /translation="MSHSPLRVAVVGLGHISQMAVLPAFSHTGSAATLTALVSDDPVK
                     RRVLAKRYGVTHTYPYKDFDACLRSGEIDAIYIALPNSLHCEYAVRAAKAGIHILCEK
                     PMAVTAAECRRMIQAAERHRVKLMIAYRLHFEACNLFTIDLVQSGRLGDPRLFHSVFT
                     QQVRAGDIRLRQQLGGGPLYDIGVYCINAARYLFRDEPTEVTALAGRGPDHRFQSVEE
                     SAGAIMRFSRDRLATFTCSFGAADAATYEVVGTKGKVRVEPAYEYVGGLKASVTIGGR
                     TSVRTFTPGDQFAPQLIYFARCVTHDRQPEPNGTEGLLDVQIIEALHRSAQRGQSITL
                     RLPAKRLRPDLTLRMHRPPVSKPQGVHTESPTL"
     gene            complement(57555..57971)
                     /locus_tag="PK063_05210"
     CDS             complement(57555..57971)
                     /locus_tag="PK063_05210"
                     /inference="COORDINATES: protein motif:HMM:NF013936.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemerythrin domain-containing protein"
                     /protein_id="HMZ96476.1"
                     /translation="MEQRPTLHETADIIKIMKNDHRHILALFQVYLGTESDSRQSIVD
                     DILQRLDDHFDWEERLFEEDSRLQEHATPVIRRVLLDHEEVKAMIHELRHAETDDDES
                     MDQFFEDMMQTVRVHFHGEERDLIPLLDAMTTAPRG"
     gene            complement(58010..59479)
                     /locus_tag="PK063_05215"
     CDS             complement(58010..59479)
                     /locus_tag="PK063_05215"
                     /inference="COORDINATES: protein motif:HMM:NF025714.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4403 family protein"
                     /protein_id="HMZ96477.1"
                     /translation="MTRHVSHILPVLFSALLVGACSHSIPKSPSKPVPPPLTSAVPTF
                     PAQTKEDSRAPVSQVPVQIKTDLTPIQTAIRKAIPERITETGHPLGQEFRWTFVRVGE
                     PDVHIQDGLVAIHAEYKGDIESRGSSRACRLDPLYTSIDATGRLTMIQNGDALSFGFE
                     PAQTAVTTKPDSDARCNMFNVPISEQLPDLFGMSEIKTALAEAVHPKEFGIPLQRIWD
                     DLGGPLSIPIASLNTRACMYGNPREMILGGQKGTTQETVISGTAKEMPFITYEATCTE
                     ATPTVALVNSGSIPPEGKPYTLVARIPLSYQQISHQLQSKLFHQSVFLDTASDTAVIE
                     RVSASDANGRALVAIDMSGDLKGTIYYWGTPRLEEGGRSISVPDLQMANESKAAIDSI
                     RIGYWQLVDRELNGKLRQAMTVDISPQVDRLKQTVTGTHRSGGTTMDILITRQQPDHV
                     RSSAQGITATIMLEGTANATGQVTLEEQSPRALLRQDVR"
     gene            complement(59556..59864)
                     /locus_tag="PK063_05220"
     CDS             complement(59556..59864)
                     /locus_tag="PK063_05220"
                     /inference="COORDINATES: protein motif:HMM:NF016836.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BON domain-containing protein"
                     /protein_id="HMZ96478.1"
                     /translation="MMKLLTHLMFAFAMMTLVACQSTTGKTAGQTIDDASITTAVQAK
                     LSQDRLSNFSRIDVDTERGVVTLNGVVKSAEQKMRVVELARGVAGVRTVNNNLQIQAP
                     "
     gene            complement(59925..60251)
                     /locus_tag="PK063_05225"
     CDS             complement(59925..60251)
                     /locus_tag="PK063_05225"
                     /inference="COORDINATES: protein motif:HMM:NF024143.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HMZ96479.1"
                     /translation="MHTDDSSNWSAFMAGALIGAGVALLLAPQSGNELRSTLRDYASR
                     AKDELDEATEQGRAAWDSAMERGQEYVEGGKQTLRKAGRAAREFVDETMQTAQNTAEE
                     ATSRRG"
BASE COUNT        12237 a        16842 c        18360 g        12403 t
ORIGIN      
        1 ccctggccgg gcgcggattc aatgaggagg tcaccgccca ttgccgccat tcgctcggta
       61 atgctgaata gaccgaagcg cgcagcaccg cttccctgat ggtccgatgg agtcgagacg
      121 aaaccgcagc cgtcatccga gacgataatt tccaaccggt ggtgttccgc gatcctgact
      181 gtcacggtcg cctgggtggc tttggcatgt ttgagcacgt tgaagagtaa ttcacgcacg
      241 gattgaaaca acaggaccgc ctggtcctcg ggaagcgcga gggccgccat ctgttgctgc
      301 atcgcgacag gaagtccgtg ccgttgcatc tgctcggcca accaggtcag cgactccaga
      361 agaccaaact ccttgagcgt ggggggcgtc aattctgcga ccaggcatcg ggtgtaatcg
      421 agtgactggg tgagggcctg atccgcgtct tgcaggagtt ccgctgtgcg atccccggat
      481 gcgccgggaa tggcctgacg caatttcatg cggacgacca ccagcagttg cgccaggtag
      541 tcatgcagtt cggtcgccag ccgtttgcgt tctttctgct ccgccagatt gagttcagtc
      601 gccaatgcac ggagttgtgt ctgcgaacgg cgcaattcgt ccgtcttctg attgaccgcg
      661 cgctccaagt cgacgctcca gcgctggagg cgttcctccg cttccttgct ttccgtgagg
      721 tcgaaactgg caccgatgta gcccaagagc tgttcagacg gtgagagggt cggcatgccg
      781 atcgtgcgca tccagcggta gaccccatct cctcgacgac aacgaaacga ggtctcgaat
      841 cggaggcgct cggcgacggc gcggcggtag gtgtcggcgg cctgggcctg atcatcggga
      901 tggacgtagt gcagccagga gagcttgctg gcctcttcga cggtggccac tccgaaaaag
      961 ttcaggcagg cctggttgac gaactccact ccctcgaggc cgttcatcca gatgatgacg
     1021 ggcgcgctgt cagccagcag gcgaaaccgg gattcactgt cgcggaggcg ctggtcagct
     1081 tcgtctcgtt cgcgcaacag acgggctttt tcttcggcga gggtgaggaa gcggtcccgc
     1141 tgtcgagcca gctcctcccg ctgcctgaag agatcgagaa agatagcggc cttactgcgc
     1201 aggacatgcg gctcgatcgg tttgtacaga aaatcgacgg cgcctgcctg gtagccacga
     1261 aaccggtgca gattgtcctg cgattctccc gtgaggaaaa tgatcgggac gtgctgcgtg
     1321 cggcgcgaac cgcgcatcag ctcggccagt tcaaatccat ccatgatcgg catatgcacg
     1381 tcgatgatgg ccagggccac atcgtgatcc agcagcatct ccaaggcctc gcggcctgag
     1441 ccggcttgca ggacttccac cccgtcttga gacaacaacg tcctgagcgc cacgaggttg
     1501 gcttcgtgat cgtcgacgag caggagcttg ggctgttttg ccggcatcat gattctcttg
     1561 gttcccgtga ggccaacagc tggttgatgt cggacaggct catggccctc gcgtcgggac
     1621 aggcagccag cgtggcttcg ggcattacgc gcgccgcggc cgattcaggc agctgcacca
     1681 gcacggtgcc gccggccttg acgaccgagc gggacccttg cgcgccgtcg tgattggctc
     1741 cgctgagtat gagtgccagc agcgttttgc cgtagacatc ggctgcggat tcgaacagca
     1801 cgtcaatgga aggccgcgca tagctcaccg gctcctcatt cgacaaggat aaggaccggt
     1861 ccttttcgac caggacatga taatccggcg gggcgaaata cacggcgccg gggcagatga
     1921 actccttgtc ctccgcctcc ttgatcgtga cccggcattt cgcctggagc aaggagggaa
     1981 tactgctggg ctgatcaggc ggcacgtgta cggtgacgag aatcggcaag ggatagtcct
     2041 gccccagcgg agggagcaat tgggtaagag aggcgatcgc cccggccgat gcgccgatga
     2101 cgatggcttc aatatcgagc aatgagaggt cgtgctgcag gacactcata ggtcgctccg
     2161 cttctgatag atccgttcca cgggtagaaa ttcgcggaag gccttcgcgt gggcattgaa
     2221 gcggagactc tccctggcgc cgattcccag gaatccattc cggaccagcg catccttaaa
     2281 gaggcccacc gcgcgatcct gcagcggccg atcgaaatag atcaggacgt tacggcagga
     2341 gatgagatgc agttcggcaa agacggaatc ggaggcgagg ctgtggtcgg aaaagaccgt
     2401 ccgccgccgg agcgttttgt caaagcaggc cgccccatac gcggcattgt agtattcgga
     2461 cagggagccg gtgccgcctg acaagcgatg gtttctggtg aacagggcga tgcgctggag
     2521 atcgtagact cccgcttccg ccttggcgag cgcagcgccg ttgatgtcgg tggcgtaaaa
     2581 catcgttttc tcttcgaggc cttcttctcg aaagagaatc gcgagggaat acagttcttc
     2641 cccggaactg catcccgcca cccacacttt caaggacggg taggtcttca agtgcggaat
     2701 gacctgctcg cggatggcgc gaaaataccc cgggtcgcgg aacatgtcgc tgacctgcac
     2761 ggtcaggtaa ctcaataact gcggaagcat cgtgtcatcg tgcagcaact gtccttgcag
     2821 cgcggagaga gacggaaatc ccatacgctc gcaggcgagg agcaggcggc gtttgagcga
     2881 cgctttggag tatccgcgga aatcatagtg ataccgggaa tacatcgcct caagaaacaa
     2941 ccggagctca atatcctcgg tgctcacggt cgtatccggc gtcatcgcgg catccataca
     3001 cgtaccagtg acaacaactg gtccacgtcg agcggtttgg ccatatagtc attcgcacca
     3061 gcggcgagcg cctgctcctg gtcgtttttc atagccttcg cggtgagggc gatgatgggc
     3121 agcttccgcc attccggttg ttcccggatc gcgcgcatgg cggtgagccc gtccatctcc
     3181 ggcatcatga tatccatcaa caccaggtcg atacgccgtt tctcccgctc tttcgattgt
     3241 tccagcaggg tgaggcattc tcgtccgttg cgggcgattt cgattttcgc cccatgaggt
     3301 tccagcacgg cgctcaaggc aaaaatattc cggacgtcgt cttcgacaat gagcacgcga
     3361 cggtcttcca ggacggcatt gcgtttccgt gctttttcca gcatgcgctg ttgctccggg
     3421 gggagggcgg tcacgacctg atgtaggaac agtgtgacct cgtcgaccag ccgttccggg
     3481 gacttggcgc ccttgatgat gatggagtga gaatacttgc ggagtcggtg ctcctcatcg
     3541 ctagacaagt cccggcctgt gtaaacgatg accggaggga aggcgaagtg ctcctcgcgg
     3601 ctcagggttt cgagcaggga aaaaccggag gcgtccggca gcgtgatgtc gagcaccatg
     3661 cagtcgaacg tccgttcgct gaggcaggcc aggcattcgg caacgctctc cgcgccgacg
     3721 gtttccacct cgtcagaccc gagcaggagc cgaaggcttt cacgttgtgt cttgtcatcc
     3781 tccacaatga ggacgcgccg cggtttgtcc gtcaggcgag actcgaattg tcggaaggcc
     3841 tcgacaagtt gttcgcgctg gaccggcttg agcagatacc cgacggcgcc cagtgagagc
     3901 gctgcttgct catagtcatg cccggacacc acatggacgg ggatatgccg ggtccggaca
     3961 tcgctcttca annnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ntcgtcaggg
     4081 tttgaggcag gataagcgtg aaggtactgc cttcccctgg agtgctggtg aggtggagtt
     4141 ctccgccgag caaccggaca aattcgcggg agatcgacaa ccccagaccc gtgcctccgt
     4201 atttccggct cgtcgtcccg tcgccctggc aaaagggttc gaagatcagg tcctgctgag
     4261 ccgcaggaat cccgactccc gtgtcctgca cggcaaaggc cagccggcca tcggggagca
     4321 tcgaaatgtc gagcgacacc tggccggctt ccgtaaactt gagcgcgttg gataagagat
     4381 tcttcagcac ctgttcgagt cgctgccaat cggattgaat ggatgacggc gtgccgggtg
     4441 cgcgagtggt gcgaagctgt atctgttttt gcgccgccag cggctggaag agcgcgtgga
     4501 gggtatcgag caaccgttgc agcgagacgt cgcccggtgt gatgtcgatg cggccggcct
     4561 cgaccttggc caggtccaac acgtcgtcga tcaaggtcaa caggtcatgg ccggccgatt
     4621 cgatggtcga ggctgatttg acctgatcgg ccgtcagatt gccctgtggg ttatcggcca
     4681 gcagcttagc gaggatcaag gtggagttga gcggcgtgcg catttcatgg gacatgttgg
     4741 ccaggaattc cgacttgtac tggctcaccc gttccaattg ctgtttttgg gcgtttgaga
     4801 tgagagccgc ttcgctgagt tcatcttttt gtgtttcgag aatctgcgcc tgttcttcca
     4861 attgggaatt cgtctgttcc aactccgcct gttgctgttc gagcctcccg tgtgattcct
     4921 tcagcgcgcg gctctgctcc tccaattcct cattggcgac ccgcagttct tcgctttgca
     4981 cctgaagctc ttcggcttgt cgctgcgttt cctcgagcaa ttcctgcaac cggcttcggt
     5041 agtgagcgga tcgcatggcc acggcgatgg attcggcgac ccgatcgatc aactctctgt
     5101 ccgattgatg caccggatga aagaacgcca attccacgac ggtattggtc agaccatcaa
     5161 caccgaatgg cgcgattaac agatgccgag gggcgcttcg cccgagtgcc gatccgacgg
     5221 taaagtaccc ctccggcaga tcttgcacga ccaacgggcg tttggcgtga agtgcttgac
     5281 cgagtaatcc atcaccagcc tggaacgtgt ccgggagcga tgtaccttcc ggcactccat
     5341 gggtcgcgac acgatggaat ctggagccgt cggcgacgaa aattgcgccg ccctgggcat
     5401 ccatatactc ggcgagctca tgcagcacat tctgaccgag ggtgataagg ctctgttccc
     5461 cgagcatgcg ttcgctcagc ctggtctggc ccacgcgtat ccattcttct ttccgcagcg
     5521 ccagcttgct ggtgatgaac tggtatccaa atgtcgccaa tgcgccggcc gtgactattc
     5581 ccatggctcg gttaataagg gacagggaag gatctatccc gaacgagctg atgacgagac
     5641 ccacgagcgt gaagagggat acggttgcgc cgacacccac gggcaccatg ggagaccagg
     5701 tgaggtacga cagcaccagt ggaacgagat ataataccca gaccgtaatg cccagcgggg
     5761 tataaaaatc cgccacgagc accattgcca ttgagagggc gatggatccg gagatgatgg
     5821 gattgggctt ctgttggaat cgaatcatga gcgactcagc agctccttcc tggctgtctg
     5881 aatcgtctga tagagatctt cgactgcagc ctccttgttc agaaacgcga cggcaccggc
     5941 ttccctcatt tcatggccta cgtgggcgat agtctgaacg gacaagccga ttacgatggt
     6001 atcggggagg gcatccttga tccgcctggt cgcctcgatc ccgtccatca ccggcatgtt
     6061 cacgtccatg aggacgactt cgggccgcca ttgcctggcc agggcaagcg cctcactgcc
     6121 gttggccgct tccgccacga cctggatgtc tccatacccg gcaaggagtc cgcacaggcc
     6181 ttgacgtacc atggcatggt cgtcggcaat cagcacccgt atctgtctgg cgctctccaa
     6241 tgggcggcca ttgatcggtt cctgatcgtc ggattgtccc agtgacggga ctgtatgcgg
     6301 gatttgagca cggcgggaag cggatggaac cctatcctgt tcggatggag gcgtaagtgg
     6361 tgcgatcaag gtcgcttccg ttccctgacc cggttgtgaa tgcacctcga ggcgcccgcc
     6421 gagggcaagc atgcgttcgc gaatactgaa caatccgaat cccgggactt gcccgccttt
     6481 gcgaagagca agatggtctg attcggcaaa gccggtacct cgatccgcca cggtgatctg
     6541 caggcatcct tcctctacgc ggacggtaat gaaggcctct ttcacggacg cgtgtttgac
     6601 cacgttcata agcagttcac gcaccgactg aaagagcagc atggcctggt cttccgggag
     6661 aggcagccgt tccggtccca gttgcagcga gacgcgtaga tcccgttgca acatttgttc
     6721 agccaaccaa ctcaaggcca tcggtaggcc gaattccttc aggatgggcg gactcagttg
     6781 tgcgaccagg gtgcgggtgt aggtcaatgc ctgattggtg acgtcctgta attcgttcag
     6841 cgttttcgca agcgggggag acaacggttg ctgcatggcc tgagccaggc gaatgcggct
     6901 gagcgccagc agttgggcca gataatcgtg tagttccgtc gccagatgtt gccgctcgcg
     6961 ttgtccggcg aggttgagct cggtggccag tgcgcgcaag tgttcccgcg attgggtcag
     7021 ttcgatggtg cgttcggcca cacgccgctc cagttcggcg gcggatcgtt gaagatcttc
     7081 ttccacgcgc ttccgttccg tgatgtcgta attgatcccg accatgcgca cgacctgtcc
     7141 ctgctcatcg gcgacggtcg cgccctggcc ggccagccag cgtatcgtgc cgtcggccgt
     7201 gagaatgcgg aactcggaag agaacacccc ggtctcgagc ccgaggcggg cggcctcctg
     7261 aacgcgtgcc acatcgtcag ggtggatggc gctgtagaag tccgaggcct ggcggatggg
     7321 gcaatcggca gaccggccga agagctcgta ttggcgctca tcccacgtcg tctcgccggt
     7381 tacaagattc aggtcccagg cgcccatccg gccggcggcc attgcgagtc gaagccgttc
     7441 ctcgcttgag cgcagcaagt cgtcggcctt ggctcgctcg atgccgaggg ccaacgttct
     7501 ggccagggtt tgcgtccatc ccacatcctc gtcgctcatc cggtgcggat gatcgaaata
     7561 caacatgaac ttgccgagga gttgaccgcc gtaggtgagg ggaacgaagg ccaatgcctg
     7621 cacgccctca tgcctgatcg tggcctgcag ctgcgggtcg agatctgctg tcgccagatc
     7681 cgggatgaag agcggaggcg gattccgctg gtctgccgac cagggggaat gaccctcgac
     7741 ggccttccgg tattcatccg acaagccacg ccaggcttta aatcgcatga cgccatcctg
     7801 gtcgaacagc agcacggacg cgcgatccgc cgagacggcg cggatcatgg cctccaaggc
     7861 tatatcgtag aggctcgcca ccggctcggc tcgattgacg gcgtcggcca gctcgtacag
     7921 catctgctgg cggccgctga gcgcgagtaa tcgggtttcc tgttgtttgc gctccgtgat
     7981 atcgagtcct acagcgacga tatggctcag gtcctggccc tcgcgtacgc cgccgacact
     8041 cacgctcatc cagatggcag tgccgtcttt gcgacgatac cgcttttcga tgacgaaatc
     8101 aggacccccg ttcacgagtt gctgaaaccg ttccagacaa tggggcagat cttcgggatc
     8161 ggtgatctgc tgcatgtgga gatcaagcag ctccgcctga tcgtatccga ggatgtcgca
     8221 gaagcgctgg ttgacgaaga cgaagcggcc ggtgagatcg gtctgtgcga ccgaagccgt
     8281 ggcctggctg acgatggcgc ggtagcgcgc ctcgctggcg gccatcagtt cttccgcccg
     8341 tatctggtcc gtggtgtctt tcgcgatgcc gatgatctgc ctggctcgcc cctccggact
     8401 gcggtcgaac accgaggcgc gcatgagaat ccatcgatag gtcccgtcgg catgcctgag
     8461 ccggtgtttg tgttccaaca cctcggcatc ggctgccgag tcaaagcggc ccagccattg
     8521 ctcgacagac ggcacatcat cggggtggac gagggtgaca atcggattgt cctgcgtcgc
     8581 cgccagctgt tcgacgtcat agccgagcac agatttcaga ctgtggttga tgtagacggt
     8641 gcgagtccgc aggaggtcga acacgaacag gagatccggt gtggacgccg caatccgctc
     8701 caggaagagt ttgctgcgag tgatttcctg ctcggccttg cggcgaatgc gcgagagatc
     8761 caggtgggtc gtcacgcggg ccatcaattc ctgtgcgctg aatggtttga cgagatagtc
     8821 atccgcgcct tgttcgagcc cctcgacacg ggattcctcg cccgccctgg cggagagcag
     8881 gatcacggga agggtatgca cggcgggatc agcgcgcaac gccttgagca gggcaatccc
     8941 gtcgagctgc ggcatcatga tgtcactcaa gaggaggtcg ggcgggtggc ggcgaatttc
     9001 gttcaacgct gccagcccat caccaaccgt gacgacgtcg taccgtctgc tcaacaagcg
     9061 ctcgatgtat tgccgcatgt cagcattgtc gtcggcgacc agcacgcgcg gacggatgac
     9121 tgcgctcgcg gcctcgctgg tcgaagccgg cggtgggatt gcttgcgtat caggcagcca
     9181 atgcagcgct tcctgaacat aggcaacggc gctcgctgac cggactgacg gctcatcacc
     9241 tgcgcggatc tgttcggcag gcaggtgggc ggttccccac gagatcctca ccgtaaaggt
     9301 gctgccttca tccagacggc tctcgacttg taccgagcct ccatgtaagc ggaccacttc
     9361 ctgtaccagt gccagaccga tgccgctgcc ttcatgggtc cggctgcgcc ggttctgcac
     9421 gcggaagaat cgctcgaaga ggcggggcag tgcctcgtcc gggatgccga ctcccgtgtc
     9481 gctgacgacc aattcggcgc ccgccgcgtc gtgccgcatc gagatggtga tctgtccctg
     9541 gaaggtgtgc ttgaaggcat tgctgagcaa attgagaacg attttttccc acatgctccg
     9601 atccacgtag acggcttccg gcagtggcgg gcaatcgaca acgaacgtga cccctgcttt
     9661 ttcaatggcg gagcggaagc cgcttgccag gtctgcgctg taggccgcga ggtcggtcgg
     9721 ttgataactg gcctcggctc gccccgcctc gatgcgcgaa aagtccaata aggtgttcac
     9781 caatttgagg agccgcaggc tattgcgatg ggcgacttcg agggcaggac tctgtggtcg
     9841 gagatgcagc tcttcctcga gcggcccgag catgagggtg agcggcgtgc ggagttcatg
     9901 gctgacgttg ctgaagaagg cggttttcgc ccgatccaat tcagccaagg cctcggcccg
     9961 gcgctgctcg gattgataag ccctggcatt gttgatggcg acggcgatat gcgagctcac
    10021 catccggaag aaatggtgat aatgctcgtc cagaggccga cggggactga tgcctgcgac
    10081 caggacgaca ccgccgtctt gggttgccgt gccaatgggc agcaggaggc attgcctcgt
    10141 cggttcaggc catgcgccgc caggcaacag gccgaacccg tccggaagct cgtccaaaag
    10201 caacgggcct ccattacgaa tggcggcggc aagaggccaa cttcccggcg ccgcattgcc
    10261 ggtcaggtcc agttgttctt gcctggccag gctggcatcc tccagcccta tgctgccggc
    10321 taactgcgcc tctcgatgat cccgatcgat ctggtagagc agggcgaagg gcacatcggc
    10381 ggagtccgtg gcgagggctt ggagaatcct ggcgcaggcg tcggtgtcgt tttgcgctga
    10441 tcccgacagc gatgccagct cacgcagcag actcgttcgc cggtcgttca gcacccggta
    10501 cgtcgtttcc tggacgatat tcagaatgcc ttcaacggct ccgctttgtc cgcgaatcgg
    10561 gttgaggctg tagtcgaaat aacattcctc cgtgtagccg aaccgttgca tcggcagcag
    10621 ctcatcagtc cgccaattcg cttctcctgt gttgagcacg ctatgaaagt aatgctggat
    10681 ggtcggccac aattccggcc agacttcgcg ggcagggtgg cccagcgccc agggatgttt
    10741 tccgccgaca acagggcgcc aggcgtcgtt gtacaggagc cagctatcgg ctccccagta
    10801 gatcgccatg ggggtttggg ctgtcaggca gacgccaagg atcgatacga gggaggcggg
    10861 ccactgttcg atggggccta gcggcgtccg gctccagtcg aatgcccgaa tgcggccacc
    10921 catctcgctg ccggtcagcc agctgaacat atcggtcgcc ttcattcccc cttccaaagt
    10981 tgtctgctgg ttgatgaggg tcggccgatc atacaggggc agagattgat tctctgcccg
    11041 gggtcactcc tcttgaatga aggacaccgc tgatgcggag cggaacctgg cgacaggcgt
    11101 ccgtccgagg gctgcaccta gcgttatttc tgtagcatga atgagacggg agcccccact
    11161 agtgaaaccc ctagtcctct gggatgagtt gagagactta tcgggcggga gaaggagagg
    11221 gaagctccgg tgcggccgtt tccatgacgc ccacggcttg ttggccggaa tccagcttga
    11281 tggtgacccg ctggccgact gaaaggtgaa caaacagttc aggttttgga atgcgaaacg
    11341 ggacttcccg gccgagatct gttcctaatc ggccctcttt tttctcgaga tcgagttgca
    11401 gcaatttccc agacacggct tcctgtgaac gaggtgccgc ttcggcaatc aggaagagag
    11461 aggtccgctc gactcccgac catgcctgta gcaacagctt cggtaccgtc ggaggcgtgg
    11521 gaatcgggtc gctgggtttc ggtggcaccg tgggtcccgg cccgggatta gggacaggcg
    11581 cagggacgtc ttgttgaacc gcctgccctc ctgtcagcag gacgactgtg agcagaccgc
    11641 ttcccatcaa ggtattcagc atcatattct ccgttcgccg gggccagcta ggcggttccg
    11701 ccggtcgatg caggcacgga ttccaacacc attttgtgac agagttccgc acaccgccgg
    11761 cattctttgg cgcagtctcc gcacatggca tggtgtggcg catgttgctc gcagacgccg
    11821 gcacagagtt cacacatttc gacacagaac gcgcaaaggc gaacggcaaa ggccgaggtc
    11881 cgtcccatcc actgcgccgc aaggaggcag atgtccgcgc aatcgcggca aagacggatg
    11941 caacgcacca tgaggtcctg ggcctcttcg tcctccgaca tgtccatgcc gatcatatcg
    12001 ttaccacagg tgttgcagat acgcgcgcaa tccaaacaag cctgtatgca atcaagtcga
    12061 tgctgatcta ctgattgaat cgatgtggac atnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12181 nnnnnnnnnn nngaaggctc ttcgcccata ctcgtccctg gacacacctg ttggcgcata
    12241 gagccagcgg aacgaatcgc gttcctcgtt gacggggagg cgtacttcca ggcgttccgt
    12301 gaggcggcgt tgcgcgcgaa acactccatg atgattgtcg ggtgggatat cgatacccag
    12361 gtcgagctgg tacgcgaaac ctctgcctcg tcggagatgc cgaccaagct cggcgagttt
    12421 ctggtggcgc tgttacgccg cagacgcagg cttcgggtgt ctgttcttaa ctgggattat
    12481 gcggtgattt atgcgctgga gcggcaatgg atgcccacgg ccgaaccggg gtggcgccgg
    12541 catcgacgtc tctcgtacca ggtcgatgac caccatccgg tgggcgcgtc gcaccatcaa
    12601 aaactcgtgg tgatcgatga tgcggtcgcc tttgtcggcg ggcttgattt gagtaagtcc
    12661 cgctgggata cgcgggagca cctttcccgg gatcctcgtc gtgtcgacgc cgacggggtc
    12721 gtctatgccc cgtttcatga cgtgcaaatg atggtcagcg gcgacgcggc gtcggctttg
    12781 ggggacctcg cgcgcaaccg gtggttcaac gcgaccggac ggcgactgtc agcgccgccc
    12841 ccacgatccg tcgaagaggt gtggccgccg agggtgaacc ccgatctgac ggaatgcccg
    12901 gtcgccatca tgcgcaccca gcctcgatac gaagagctgg aagagcaacg cgagatcgaa
    12961 caggcgtatc tgagtgccat caaacgcgcg cgtcgatcga tttacatcga gtcgcaatat
    13021 ttcaccgctc aagccattag tcatgcgctc gcccaacggc tgtccgagca tgacgggccg
    13081 gatgtggtgt tggtgctccg tcagcattgc gacgggtggc tggagcgccg gacgatggac
    13141 agtttgcgcg cccaactcct ccacgaagtg gaactggctg accactatgg ccggctgcgt
    13201 gtgtatgcgc cggtcgtgcc gggagaggcg ggcgccgaac cggttgccgt gcatagcaaa
    13261 cttctggttg tcgatgacga attcgtctgc atcggatccg ccaatgtctc caatcgttcc
    13321 atgggattcg acacggagtg caacctggca gtcgaggcgt gcggccaggc acgagtgcaa
    13381 tccgccattg cggcgtttcg caacggattg ctggcggaac atcttggcgt cgatcccgaa
    13441 gtggtcgcca atcagattca aacctgcggg tcgctcgcgg cggcgactga cgcattgcgc
    13501 gggggcggcc ggaccctggc cgacgactgt tttgaagcga tgcctccttc cgatgcaatg
    13561 attcctgaac atgcgctggt cgatccggag cgtcccatgg ccgcggatca tcttctggcc
    13621 ggcgtgggat tccggcggga gcggtcgcgg atcgtccggc gcgccatggc gggcctcacg
    13681 ttgctggcag gaatggcgat actcgcggcc gcctggcgat ggacggctct gggacaattn
    13741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnc tgggctcata tcggatccgg
    13861 cgattggctg gttctcgtgt tgaacatctg agtcgacgta tggccgaacg agggctttgg
    13921 gccgtgctcc tggtgagaat cctcccgatc gcaccgttct cggtcatcaa tctgattgcc
    13981 ggtgcctcat cggtgtcatg gcgacacttt gtgctgggca ccgttgtggg catgttgccg
    14041 ggaatcgcca tcatggcgac cttcgtgagc ggtctcgaag aagccgtcag ggaaccgagt
    14101 tggcaggcct tctcgatggt ggggttggtc gtcgccgcgg cctgggctgg cgtgtggtac
    14161 gtatcgagcc gactgcagtc caggcagtcg actgagagtg tcatggccgc cggttcctcg
    14221 gttccagcga cgtaggtcct tcagcaaagg ggtgccatcg atgcgtgtgc aggtggcctc
    14281 gtacaatatt caccgcggag tcggaaggga cggacgctat aatcccgggc gaattctgcg
    14341 cgtgctacag gaggtgaacg cggatattgt cgcgctccag gaagtggatt ttcccggccc
    14401 gcatccgcat cactttttga cgtggctggc tgctcagcta ggtatgacgg ccgtgggtgg
    14461 accggtgcga acatcggcgg caggcaccta cggcaacgcg ttgttgacgc ggtatccggt
    14521 gagaaacgtc aggcgatggg atctttcagt cggaagacat gagccacgag gcgccctggc
    14581 tgcggacatg ctctgtcagg gcgcgatgat tcacgtagtg acgacacact tgggactgtg
    14641 gccgacggag cggcctcggc aggccaccaa attgctggag ggtttacacg tcacagaaga
    14701 agagttgacg attctcatgg gcgacctgaa cgaatggcaa ttgtggggga agtcgctgcg
    14761 ggtgctccgc aaggtgttcg gggcgcccgt ctcgccaccg acctttccca cggcctggcc
    14821 tctgttggcg ttggatcgga tttgggtctc tccgcccagg gcattattcg aggtccacac
    14881 ccatcagtcg cgccagagtc gcaccgcctc cgaccacctt ccggtgaagg cggagatccg
    14941 gtttgagtcc gtgcatggca cagggtctgt gatgcgggag gactacgaac cgacgcctac
    15001 ttcaacaggc tgtggccgtt caatgctgta gcggccatat cccaggtggc tcaagcgtag
    15061 ctgtcccata cggctcaacc ggtcgacctc tgaaaatacc tggttccagg tgagagtcgg
    15121 gcaggcttcc accagcatgt ccatatcgca ctgctgcatg tggtcaaacg catcgaggat
    15181 ggtgggggtc acgctgttgt cgatttcagg ctgctcttcg gtcactgcag ggcgagcagt
    15241 tctccccaac ttggtaaatt gcacggcgca tgcggggcag taggtgtggg tgagacgata
    15301 ccctccgatg gtcaggtgat gcgtatcgag atacgtcttt agagggcccc actcgggctc
    15361 ggtcccgggt gacagagtct cgcctcgcac attttcacat acgcagcaga tggggataaa
    15421 cttcttcatc tctgtcttca taacccaccc ctctcttctt gtcggaatga actgcaaccg
    15481 gtcaactagt gtcgcactgt agaaaatatt ctgccctccg actactaggt gctcccctag
    15541 ttctcgcccg tcatgatgtg gaggggcgag gagtgggcct ggctcaacgc tcaagctgta
    15601 ctttaccttc gaggccgggc aggaccgcgt cgaagaaggc gttttggaag agggtcagca
    15661 ccagttccca ggtgctcgct tgggggtttt ccaccgttcc ggacaggtca gttttcgtgg
    15721 cgacttcatc ccgcggggtg tttttgagaa tttcagctaa cgcattgatg gtcttttcgt
    15781 acagctggtt gagcatcccc ttatcccggt cctgttgcgg atcataggcc gtcacatcct
    15841 taaacagggg ctttaagtat cccttgacgg tgccgttttt gacgttcacc tcgctgaaca
    15901 gcgaaaacag gccggccgcg gcatccagac ccccgtaggc gcgcaacaat tgattgagag
    15961 atttcacctg cgttttgacg atcttcacag aaaggtcaaa gtccggggat tcgacttccg
    16021 gcctgaacgc cccggtaatc ttggtcgcgc cggtccccat caacatgccc ttgagttgca
    16081 cccgcgccgt gccttcggag agctggttgc tccagttctc aagctccagc tccgtcccgc
    16141 tgatgaacag gcgataggaa ggattcgtcg cctggtttac aaacccgaac tcactgcgtt
    16201 cgactttccc ctggtctatc cgaaggagga gcgtcggatg gttggcagct ttcgccgccg
    16261 tccggctcac ctgttgtgcc gtacgttgct cgcgctgttt cgtccgggct gcatgaacaa
    16321 agtccacctt cacatcatga aggttcagcg aagcgatccg cacttcttgc gccgcagggg
    16381 caaattccac atgaccgcta gtcgtcaatg aaccttgggt gaggtggatt tggcgttgag
    16441 cggtgagggg gagcaggtcg gccaggttga tgtcctgcag cgtgatgtcc acatcgacgc
    16501 ccatcgacgg ttcggcaaaa aagtccgcat gcccatcgac tttcatgtgg cctccaccgg
    16561 ccaccatcgc ttcgacctgc acccgcgagg ggtactgtaa cggtttcgac ctcacgtttc
    16621 gaatgttctc cgccaggacc tgaatgttcg tcaggcgtat gggattggac gtcgcgttct
    16681 ctcgataggt cacgtcgccg tccttgatac tgagttcatt gatttgtagc gggtagacgg
    16741 cgaagagggc ctcctgccaa cttttctttt gagccggcgc gtcctgcagt tcttgagccg
    16801 cttggggtcg ggtgaagtga atgagaggac ggtcaatgat gtgatcgctg accaggcggc
    16861 cggatagcag cccctcccac tggatgctgg catgccattc cgcgatgtgt gcgagtggtg
    16921 gatccggatg ggcctcctgg ataacggtta cgttttccaa gtccacagac aggccaatag
    16981 gatgaaagtc gagcgtaccg atatggaagg tgtagcccgc gatacggccg ttcaactgac
    17041 gttcggcata gacccgcaag ggttcatcga caaaccataa ccctattcca cccaggagaa
    17101 tcacggccgc acaggcagcc atgacccagc gccacatgcc gcgatggtgt ttcttgacag
    17161 acgatgcggc atgcagactc tcacccgtgt aggtcgtctg tcggctatcg atccgaatgc
    17221 tcataaccgt ctgacccgct gaataacgac acctacctca agaaaccccc gacctgtcgg
    17281 cggaataaca cgacatggac attgcgctcg gatcgtaatg ccgctttgcc tgctcggcta
    17341 ctgggaaggc ccctggtttc gagaaggcgt gcagccgaga atcggccctt ttcggctcta
    17401 gggtaatgcc gagttatgcg cggcagacgg agcgtgacag tgtaactgcg gacgtaagca
    17461 ggtgaggatc gctctacttc tcgtcagccg aattgaagcg tcaggtcctt acgattggca
    17521 tctcgctaga ccctgccatt acgaacgatc atttcacgtc gagaggggcc cgcaagatgg
    17581 cacacacatg gaagacgctg ctgcaaccgc aatccttgtg gaaactgctt caggaagctt
    17641 tcacggcctg gagtgatgac aagattccgc ggcacggggc cgcgttggcc tactataccg
    17701 tgttgtcgct ggtgcctctc ctgatcgtga tgatctccct catcggactg atcttcgggc
    17761 gggaagcggc gcagaaacac attttggatc aaaccaccaa tctgatgggg ccgcaaagcg
    17821 gggacgcggt caagcaaatg atcgagcatg ccacgcagcc caccacggga acgatcgcca
    17881 tgctgatcgg cgtagccacg ctgctgttgg gcgcgtcagg cgtattcgcg caactccagg
    17941 actcgctgaa tacgatctgg agagtagagc cgaaagaggg gcgcggcttg tggggactca
    18001 ttcgcgatcg atttatctcg atcagcgcgg tgctgggtac agggttcctg ctgctcgtgt
    18061 ctctggttct cagtgcggca ttggcggcct tcgggaaatg gtatagcggg tggcttccgg
    18121 cgcccgaggt ggtgctccaa ctcttggaaa tcgtgatttc gttgctggtg attgcgggac
    18181 tctttgcctt gatgttcaag gtgcttcccg atgcccgcat cgcgtggaat gatgtgtggg
    18241 taggagccct gttgacggcg ttcctgttta cgatcggtaa attcgccatt ggcctgtatc
    18301 tgggaaaaag cgatgtgggg tccgcctatg ggtcggccgg atcactcgtc atcatgttgg
    18361 tctgggtgta ctactccgcg cagatcgtcc tgttcggggc agaattcacg caggtctatg
    18421 ccaatgagct cgggagccgg atcgtcccga cggagaatgc cgtcccggcc gatgagccaa
    18481 gggccggacg catgcgccca gcaccgacac agccaagatt gcaggcggca tccggtcggc
    18541 aagcacaggc tgcctcagct cagcgtcagc ctgcagagcg cctcccttgg tggggaacag
    18601 tcctgctgtt atgggtggca gtaacccgct tcccacggcg ttcggaatga acaatgaaca
    18661 gggaccgaga tggaatggag gagcggccag aaccgcgtga acgattgagg tgaacggttg
    18721 agagggcagg catcaaacga cgatatgaag agaggaacaa cacgtatggc tggaaagcag
    18781 gatatgaaga cgaatcaggg gcatggtgga gaaacgcatc agcaggcagg gggacccaaa
    18841 gagccggtgt tgacgaccga ccagggcatt cccatttccg acaatcaaaa cagcctcaag
    18901 agcggtgcgc gaggccccac gctgctggaa gatttcgtgc tgcgggaaaa aatcttccat
    18961 ttcgatcatg agcggatacc ggagcgcatt gtgcacgcgc ggggatcggc cgcgcatgga
    19021 ttctttgaag tgtacgaatc gctttcatca ttgacgagcg ccgatctgtt tcaacgcaaa
    19081 ggcgaacgga cgcctgtctt cgtgcggttt tcaaccgtcg tcggtggcgc cggctccgtc
    19141 gatactcccc gtgatgtgcg cggttttgcc gtcaagttct acaccaagac ggggaattgg
    19201 gacctggtcg gcaataatat tcctgtcttt tttatacaag atgccatgaa gtttcccgac
    19261 ctcgtccacg ccgtcaagat ggaggcagac agcggtttcc cgcaggcggc cagcgcgcac
    19321 gatacctttt gggattgggc gtcgctcatg ccggaaagca cgcatatgtt gatgtgggcc
    19381 atgtccgacc ggactcttcc gcgatcgttt cgtatgatgg agggctttgg cgttcatact
    19441 ttcaagctgg tcaatgacaa aggcaaagag acgttcgtga agtttcactg gaaaccgaaa
    19501 ctcggcctgc aatcgacagt ctgggaagaa acgctgaagt tgcaggcggc cgataacgat
    19561 taccaccggc gtgatttgcg ggaggccatc gatgcgggga attttccgga gtgggaattg
    19621 ggcatccaga cgttcgatca ggcgtttgcg gataaacagc cgtatgacgt cctcgatgcg
    19681 accaaactga ttccggaaga acagattcct gtccgacgca tcgggcgcct ggtgctggac
    19741 cgcaatcctg acaatcactt cgcggaaaac gaacaggtcg ccttttgtcc cgccaacatc
    19801 gtgcccggca ttgatttttc gaacgatccg ctgctgcaag gacggttgtt ttcgtatctc
    19861 gatacgcaga agtcccggtt ggggaccgcc aattttcacc aactgccgat caacgcgccg
    19921 aagtgtccaa tggccaactt tcagcgcgac ggccagatgc agatgcgagt gccgaccggc
    19981 cgggccaact acgagccgaa tagtctggct gcccatgggg aggaaggtgg tcccagggaa
    20041 agcccgcagg gattcaccac cgcaccgggc cgtgacgatc gggaggaaca gggcgataaa
    20101 ctccgcgttc gtcccgaact ctttgccgat cattacagtc aggcccgcat gttctggaaa
    20161 tccctcacgg acaatgagca ggcccatctc gcatcagcgt ttgtcttcga gctggcaaag
    20221 gtcaacctcg acgaggttca gtcgcgtatg gtcggcaggc tgcggaacgt ggatgagggg
    20281 ctggcgaagc ggatcgcgga tggtcttggc atgccgctcc ctgggaagat tcgcgcggcc
    20341 agggagccga tcgagatgaa gccgagccct gctctgtcga tccagaaaaa tatgctggcg
    20401 acgttgaagg gacgcaaggt cggcctgctc tatgcggaag gatcgaacgg cggggacatc
    20461 gatcgaatga tcaaacaggt cgagaaggcc ggcgggaccg tctttcttgt tgcgcccaag
    20521 ctccacggga cgaaactgga gaacggcaag gaattgaagg ccgacgggca actggctgcc
    20581 tcaccgtctc agttattcga tgctgtggcc atcatcctct cggccaaagg cgcgcagatg
    20641 ttgctcaaag agggggcggc gattcaattc gtcatggatg cgttcgggca tctcaaggcg
    20701 attggccatt cggaggcggc gcagcctctg ttggacaaag ccggtgtggt accggatgaa
    20761 ggcgtgaccg atctgcgagg gtcattcgtg gaggcagccg ccaagcgctt ttttgctcgc
    20821 gaaccgtccg tgcgtacgtt ggcgtagcag gcatcctcag cgttggagtg gaaccacgga
    20881 caggtatggg gggagtgaaa gcccgggctg gtgtgcgatg cctctatcga cagacatcgc
    20941 acaccagcag ccgtttctgc tttactgaac cgtgatggaa cctttcgtgt cagccatcgt
    21001 tgttcgcgta tcgctcgaag gcctgaccga gtagttcacg gtgccgaccc ggctgaaaca
    21061 gagtccggcc gtttcattgc tcgccaacgt ggtggaatta tcgacgccca tccctagcgc
    21121 cttggagaat ccgttgcggc aggacacatt gtgctccagg gggccgtcaa ttgtgaccgt
    21181 cacggaatcc tgtcgctgat tgatccagcg aacctcgtcg cccgcccgca ccgtcaaggc
    21241 atcgggagtg agcgtatctt tgatcacgat atttttcacc atgcctgttt tggtgcctac
    21301 gtccatttct gaccgggtct tcgaggcggt tggtgaactc gagcaggcgg ccaacgacac
    21361 cagcgcgagg gcaagtagtg agtgcatcaa tgtcttcatg ggtaatcctc cttggtaaga
    21421 tgaaatgatc gcgacatcac cgcgacgtgc cgctgatgcg ataggccatg tgtcctctgt
    21481 gggagtgcga ggcctccatg cccacagtac tcagcacgat gacgactccg tactcgggaa
    21541 agccccagta tgcgtcaggc ggccggatgg ttattcatga agaaagactg agcgggtgag
    21601 ggggcatgag tccatctgaa atcattcgaa aaagcggagg ttcagcgttc catcggctga
    21661 cgggcctgct actcacgctc gtcttgctcc tgagcggctg tgccctctcc ttcgggtatc
    21721 ggcatgctga ctggctcatc acgaggcaac tggatcatta cttggactta acgtcgagcc
    21781 agcggcgcat cgtcaacgcc cgcctgcagc cattgctctg gcggcaccgc atcgaagcgt
    21841 taccgcagta cgaacagttt ctcaaagatc ttcacgcccg catcggcagg gggttgacct
    21901 ccgaagacgt agaatggact tttgcctcct acgatcggtt tcgggcagat ctgtttgagc
    21961 gggccattcc cgaagggacg cagctggcga tgctcctgaa gaataaccag atcacctatc
    22021 tggaacgggt gtttcgcaag gaggaggttc aagcggagag tctggcgcga cgatcagttt
    22081 ctacgcgcct tgatgaacgt gcgagaaaag ggatcgcgac ggctgaagaa tggcttggac
    22141 ctctgagcca cgagcaatcc gttcagcttc gcgagatgat gttggctctg cctgacagtc
    22201 aaccgacgtg gtggcagtac cgtcgacagc ggcatggtga ggtgctggcc atgctccgca
    22261 cttccacctc cgccgatcag attgcggagc ggttacgata cctgtttgtt caatccgatc
    22321 agacggcccc gaccggttac ctcaagatga tgacggaaat gcgcgcggca ctgacgcgta
    22381 tggtcctgga cgtggatcgc atgctgacac cggctcagcg acgtcatgtg ctggtcgcga
    22441 ttcagaaggt gatcgacgag gtacatgcat tagcgcacaa ttcgtaacta gaagtggacc
    22501 accccgaaaa gccacagcaa cagaatcaaa ctcagcggca cgccaagcag ccataatata
    22561 atcggcatag tctctctcct tcgtcatcac actcgttgaa atgatcggaa gggaggggca
    22621 ccgaactggg ttcgctaccc ctcgccctcc gacagagcgg acattcccgg acggatggaa
    22681 atgtgcgctg ctattgtcac gatgcaatgg aacagtgtga tgcggtacta ggtgaagccc
    22741 ttgggaacga gatgctgggc tgcgggtatt acgcaggttc gatccctgtg gcaggtaccg
    22801 tgtactgttc ttcaatggcc gcgcgaatga gccgccggct ttcctcggct gagagctccg
    22861 gtcgggcttc aatgtcgtgg accaccttgg agagggtttc atccttgatc atgtcgctga
    22921 tccacgtgga atagtcatgg gcgttaagat ggtactgcca ggtttgttca tcgacgccct
    22981 cgccgagctg cataaagagc aagaggtttt gcgcccgcaa attcaatttc cccgccggac
    23041 ctctaaaata aaaactgcgg tccggcggaa gttcgccttc cgcatacttg cgtctatgtc
    23101 tccggcgttc agtgctgctg ggggcaattt cgaggacttc aggcgcgact gctaacgttg
    23161 gatcccacat gagagtctga ccggcttcga gttctgttga gggcaaggtt ggagcttgct
    23221 gtcctcttgc ttggcaaaag gcctcgatgg tcttccccgg tgattgcccg agggcgaaca
    23281 ccagatccac tgttttgaga atggccgggt caatctgatc ggggtgtacg gtcacataca
    23341 tcatgcccgt gcagtcttgc gtcaggcccg gggcgccggg attgccgtcg cgcgggagaa
    23401 gatggtgcgt ttcatcgatc aagatccaat gcgggcgacc gcttgccgcg cgcaattcca
    23461 gaatcttgtg gagcagaccg aagaaaaacg ccggccggtc atgtaacgga agcccgacga
    23521 ggttcaccac gacatgtgtc tgcgggtttg cgagagctgt caggatttcg gtgaggctgg
    23581 gaccattctg ggcggtnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    23641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnngaca
    23701 gctccagacg ggccagcgcc gccgtcaacc cggtggcttt gttgatgcca tgcggcagca
    23761 ccatgacggc gcccttattg aaaatgatgc gaagttccag tccaagatcg cggatgatgt
    23821 cgaggatcac ggtttcgtag gggacacggg tggcgacaat gacatgtccg aggctgagat
    23881 gctggactgc gcgacgttgg acctcttcga gaaatgccgg tcgtggggcg tcggccagaa
    23941 gagtcacctc ttttgtggcg gggcggtaca acacaccgcc gttctctgcc accactaatt
    24001 cgcacaacga aatctgcgga aaaatgtcca gcagctccgg caggattcga cccgtgacga
    24061 gaatgagttt gcggccggaa gcgacgagcc gttcgagggc ggcgacggtt tcgggatata
    24121 cggctccgtc tgacgccagg gtgccgtcgt aatctgctgc caaggccata taacgcatcg
    24181 gttcgtcctt tccccaatca tttgccgtga cccagtgcga tgtatacaag cttccaacag
    24241 tcggtggagc taggaaggag cctagggagt ttccgagtcg gcgggcatct gctttcatgc
    24301 cagaaaaaga tgagtgaata tccaatgagt tacagtggaa ggattcatct catcgcgggg
    24361 tggtgcgggc ttgtgctgat cgtcggtgga tgcaccaccg tgcttccgcc agccgatcat
    24421 ggtgccgcca acgagtcgag ccaacgctgc gtgcctgcga tgacgaagcg ggcgcgagtg
    24481 gctgcggccg gggatgaaac gcctgtgaca cccaccacgg aagcccgctc cagattcagt
    24541 tcagatgcct tgcaggtcgc ggaggtcgtg ggtgtcctcc ccctggtcaa tcaccttgcg
    24601 agtgacaccg gatcatcgcg gcgggatcct ctggcatccg tcgttctccg tcagcggctc
    24661 acggaaatcc ttctgctgac cctctttgag atcacctcga cgacggccga actcacctgc
    24721 gaacgtgatc gagccgatca agtggcggat cgcatcgatg aaatcgatgg agcccgggtg
    24781 aagcggttga cgatcgcctc gatcctcttc gggggaattg ccagcatcgt ctcggggggg
    24841 atcgggttgg ctgctggcgc tagcgtgggc ggggaggctg ccgatgtggc cggaggggct
    24901 ctggcgtcct ggttcggggt gtcagcctta ttcacgcatt ctgaggtgga atttcgtcat
    24961 gagcgcaacg tgctccagga aatctgggaa gatccctcgc aaccgcgcct cttttctccc
    25021 accatctggc ggtacttgca tcgagcgcat gacgaaaagg gaaagcttcc gcgggagcag
    25081 gtccttgact catggcagca ggcaggcagg atgggagaaa acgggtcacc ctccgagcag
    25141 gaacggcgcc gcttattttt cggcgcaggc ggccggtacg gggcggcgga attacatgcg
    25201 cgcgcgtcta tgctggagac gctggaagcc tcgatccggt tgctctatga agagttggaa
    25261 gtgctgatgc gtgaactggc cgaagagacc gccgacgtct catgaatgtc accagaggag
    25321 tcagaccatg gtttccaaac acacgaaaac gcgggattca ggactcttcg tgcggtttgc
    25381 caatgaggct tcgcgggtgg tgggcagcgc cggcgcgttc ggcgtggcga ttgtcgtggt
    25441 gttgctgtgg agcctgtcag ggccgctgtt cggttacagt gatacgtggc aactggtcat
    25501 caacacgggg acgaccattg tcaccttcct catggtgttt ctgattcaga atacccaaaa
    25561 ccgggatagc gccgccacgc agctgaaact tgatgaactg atccgctcga cacaaggtgc
    25621 ccacaacgcg ttgctcgacc tggaaaagct gagctcgaaa gacctcgaag acatccggat
    25681 gctatatcag aagttggcgg accgggcccg ccgcgaaaag aaaggcgggt gggaagacac
    25741 ggatacgccc gagctcaagc gggtgtgagg ccgatcaagt cggcgtacgt tcctttcgct
    25801 tgaccggcgc gagatcagta atggcaggtc cattcaggac cttcccgaac cgatcgaagc
    25861 gcgatccatg acaggggcaa tcccaggtgt gctcggaatg gttccaggag acgatgcaat
    25921 tgaggtgagt acaaacagcc gaacaggtgt gcagcgtgcc atcggcatca cggtaggccg
    25981 caattttcgt gaggccgtct ctcagtactg cgccctgatc gttggcaata tcctcctccc
    26041 gttcgacatc ccctttcgtc acccaatcgg tatattgcgc caccacattg agtgactcgc
    26101 gcacaaattc tcccatcgcc ttcacgggct ggcgggaagg attatagaga gatgcccaag
    26161 ggcattcccg gcccatgatg aggtcggtca ggagcagacc ggcaatggtt ccgtgggtca
    26221 tacccatccc gcagtcaccg gtcgcaatgt agatattgtc gacatcgccc ggatttttac
    26281 cgatgaacgc caagccatcg accgtttcca tcacttgtcc cgaccatcga taggagactg
    26341 ctcccatggc aggaaaatat tcgcgggccc aggtttccag acggccgtag cgcctttccg
    26401 catcgtcggc ctgaccggcc ttatggtctt cgccgccgac gataagaagg agttcctcgc
    26461 gcccgtcggg aaacgaatgt cgctgcgtcc gcacgtagtg atagggatcc tgaatatccc
    26521 accacaacgc ttgttcaatg gcttcagcgg gaatcggcgc tccgatgaca taggtgatat
    26581 aggccgcctg cttggtatga atcgccacca tgttattgat gggcgtattg gtggcgacga
    26641 cgacggcatc cgccgtgacg acgcatcctt gactcgtttc cacccgggcc tgtttgccgc
    26701 tttccacctt ggtgacatgc gcgccgctga atgcccggca tcctcctgac tggagcgctt
    26761 tgacaaggcc ggccaggtat ttgagcgggt gaaactgccc ctgatgcggg tatcgcaggc
    26821 agggaccgtt cttggccagg gggcctgctg gtctcgtgac atgttcgact tcgctgaggc
    26881 ctgcacgcaa aacggccatc cattcgtctt tgatgtgctg cgcgtcgtcc ggagaggcag
    26941 cgcagagata tccgtccacc cgaagaaagt cgcagtcgat cctggcgtct ttgatggtct
    27001 tttcgatcca gtcgatggcg gccgtatgac tttccgcagc caggcgggcc cctgatcgac
    27061 cgtgcaaacg ttcaatgtcc agatatccgg aatcgatggc gttcgagagg tgnnnnnnnn
    27121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    27181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnattgatgg tctgtccata cgattgtcac
    27241 ttctgcgccg atccaacctg ccgggtggat gggtgccagc ttgtcgaggc cacgatgttg
    27301 ctcgtctgcg acgagtgcgg agagccggtg ctgtgcgtga actgtgcgca tgtgtgcgtc
    27361 acttgtatgc aggcctcgcc gcctcggcct acccctaaca aataggtgcc ccatgccacg
    27421 ctccctctgg aaaggatcga tcagtttcgg cctggtcaat attccggtgg tgctctactc
    27481 ggccgaaaac cggaacagtt ttgaccttac cctgttagac cggcgcgaca tgaagccggt
    27541 cgggtttaaa cgctacaaca aggagagcgg gaaagaagtc acgtgggatc aaatcgtcaa
    27601 aggatatgag tacgacaaaa accggtatgt cgtgctcacc gatgaggatt tcaagcgcgc
    27661 caatgtggaa gcgacacaaa cgatcgacat cgtcaatttc gtgcgggcag aagagattgc
    27721 ccccacgtcg tttgagacgc cctattatct cgccccggat aagcatggtg agaagggcta
    27781 tgcgctgttg cgcgagacgt tgaaaaagac cggtaaggcg gccatcgcca ccgtagtgat
    27841 ccgtacgcgg caatacattg cggcattgat tccctggagc gagatgatgg tgttgaatac
    27901 gctgcggtat gccaacgaaa tccgctccag caaggagctc gatctgcccg ccaaacatga
    27961 aaagtcggca caggtgacac cgcgcgaagt ggacatggcc atgaagctcg tcgaggaaat
    28021 gtccgaaccg tggaaacccg agcgctacaa agatacctat catgaagatt tgatgcggtt
    28081 gatcgaaaag cgcatcaagg ccggtaaaac ggaagtggtc acgacacccg ggaaagagga
    28141 aggcggggag aagcccggtc gcgccaaggt ggtcgatttg atggctcttc tcaagcgcag
    28201 tgttcaacag tccggtcatt ccaaacaccc tgctcgtgag aaagagcggt cgccacggcg
    28261 taagagcgcc tgaggtcact cagattggct gtagacagtg gagggctann nnnnnnnnnn
    28321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    28381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnta tccggacccc tgctcgcgtt tccagcctga
    28441 gggaccccac ggcccatcac tgattgtcga ccccggcgca tacacctggc atgatgaccg
    28501 gtggcccggc gtcgccatgc atgggcaggt gatctacgaa cttcacatcg gtaccttcac
    28561 ccctgaaggc acattcgaag ctgccatcga gcggctcgac ggtttgaaag aaatcggcat
    28621 tactgtcatc gaagtcatgc ctgtggcgga atttccgggt cgctggaact ggggctacga
    28681 tggcgtcggc ctgtatgcct cggcccatgt gtatggcgac gcgaacagct tcaagcgctt
    28741 cgtggacgaa gcgcaccggc gtggactcgg cgtcatattg gatgtggtgt acaaccacct
    28801 ggggcccgac gggaattact tgccgacatt cagcgctgag tatttcaccg atcggtatcc
    28861 gaatgaatgg gggcaggcga tcaatttcga cggccccggt tcagggccgg tgcgtgattt
    28921 ttttattcag aacgcctgct actggatccg cgaataccac gtcgatggat tgcgcttaga
    28981 cgcggtccat gcgtttcatg atgccagccc cgtgcatgtc gtcgcggaat tgtctcgagc
    29041 ggccaggcaa gcggccggac cccgttccat cattctggtc gccgaatgtg aagcgcagtg
    29101 ggtccagacc attcagccgt tggcggaagg aggctggggg ctcgacggcg tatggagtga
    29161 agacttccac catacggtgc gcgtggcggc aaccgggcgc agcgagggct actacaacga
    29221 ttatcgaggc acgccgcaag aattcatttc ctgtgtgaaa cgggcgtttc tctaccaggg
    29281 gcagcgatat cagtggcaag ggaagccacg gggcacggtg gtgtcggaag agccggccga
    29341 agggttcgtg ttttttctgc agaaccacga tcagatcgcg aatcagttgt ggggcgatcg
    29401 cttacatcag aaagtcagtc catccgtgta tcgcgctctg acggctctcc tgctcttggc
    29461 cccggagacg cccctgttgt tcatgggaca ggaattcgca gcctcctcgc cgtttttatt
    29521 ttttaccgat ttccccccgg ggcaattagc gaacgacatt caccaaggac gaaaacaatt
    29581 cctgtctcag tttcccagtt atgcgtcgag tgctgcgcag gacgcaatcg gtgaccccag
    29641 cgcgccggcc atgttcgagc gctcgaaatt ggattggacg gaacgggagc gccacgccgg
    29701 aatcgtggcg ttgcatcgag acctgttgcg tcttcgtcgg gaagacgatg tcatcgcaca
    29761 acagcggcgt gatcgggtgg atggggccgt catcgggcct tcggcgtttc tcctccggta
    29821 tgccggtcag catggcgata atcgcttgct gctcgtgaat ctggggcccg acttggattt
    29881 tcgtcctgct ccggagccgc tccttgcgcc gccaagcggg cgtatgtgga cgtttcgctg
    29941 gtccagcgat gccccgagtt acggaggacc gggagtcatc gagccgttga ccgaaaccgg
    30001 ctggaaaatt cccgggggtg cggccttcct gtacgccgct ctggacgata catccaagga
    30061 cactggcaag actcccgcga tggcgagccc gcatgaagag gaatcgcgat gacgacaatg
    30121 gccgatgcga tggtgctgac ggtccctccg gagcggctcc gtgatcctaa cgcctttctc
    30181 gccagagaat ggctggtgac gaacggtctc ggcggctatg cctcgcaaag cctgttgtgc
    30241 gctcccacac ggagatacca cggtctgttc gtgcctgatc tgccggcccc ttgggggcgc
    30301 acggtcatga tgcctcgttt tgacgacgaa gtgctggtcg atggcgatgc ggtctttttg
    30361 agtggtgtgg aattttccga tggccggctg gaaagcaatc ttctgtcggt attcgacggc
    30421 ttcagccggg aacggcagac gccagtctgg cgcatccggg tcaaaggccg ccggctggaa
    30481 aagcgcgtga tcatgcccta tggccacaac tccgtctacg tggaataccg ccttcttgag
    30541 ggtgatccgg tcggcctgcg gcttcgcccg ttcgtcacct tccggatgct tgatgcgaga
    30601 ttgcacgatg ccaagcgacc gcctttccct ctcaccgtcc tgaatggccg gtacgacatg
    30661 catctgtgcg aaggagcgcc ttcgttaaaa ttgtgcttgc gtccccacgg agggaagttc
    30721 gtggcggatt acgagctgag tgtcgatgtg tcctaccggg tcgatcgcga tcgaggctcg
    30781 gagcatatcg agagcctcgc cagccccggc tattttgtgg cggaccttac gcaggatcgg
    30841 cccctcgcgt ttgttgccag cacggaaccg tgggaactgc tcgaattcga ccccgaagcc
    30901 atttttgagg cagaggccaa acgcctgggt aaattgctgt cccaacgggc aggcgaagcg
    30961 gatgacgaca tcgaaggttg gctgaccatg gcggccgatc agtttgtcgt cgccccggga
    31021 tctcgactgg aggagcaggc gctggcgcga gcctccggaa atgaagcgcg cacgattatc
    31081 gcggggtacc attggttcac ggattggggc cgcgatacga tgatcagctt ggaaggtctc
    31141 acactctgta ccgggcgcca tcaggaagcc cgagccatcc tccgaacctt tgccaattat
    31201 gtgaaagatg gattgattcc gaatctcttc cccgaaggag agcggatggg cctctaccac
    31261 acggcggatg cgacgctgtg gtattttcac gcgatcagcc ggtattaccg ggtcacgaac
    31321 gaccgtgaga cgctgttgac cttgttgccc gtcctccggt ccgtgcttga gcaccatgtt
    31381 cggggtacac acttcggaat cggtgtggat gcgaaagatg gactcttgcg cgcctcggcg
    31441 gaaggttacc aactgacctg gatggacgcc ttggtggatg gctgggtggt gacaccccgt
    31501 cggggaaaac cggtcgagat ccaggcgctg tggtacaacg cacttcggtg tatggaggag
    31561 tgggaagtac ttgccggtca gacgccgtcc cgttggagag acctagcgga acaggtgcaa
    31621 cgctcgttta acgagcggtt ctggattgcc gcagagggct acctctacga cgtcatcgat
    31681 ggcgagcgnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    31741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnca cctgctggat
    31801 gacgggatcg ggacggtcag cgaaattttt gacgcagaag ctccctttca tccgcggggc
    31861 tgcattgctc aggcctggag cgtcgccgag gtgttacgag cctatcgaaa cacgcgagcc
    31921 gagaaggaga gggtgtgagg gattgtgggt gtggcgcgta tcggtacgtc gggatggcat
    31981 tacgcacatt ggcgcggacc ctattatccg cccagtgtcc cgccgcgagc gatgctggat
    32041 tattacgccc gtgatctgga taccgtcgag atcaacaaca gcttttaccg cctgccccca
    32101 tcggggacgt ttgagggatg gaagaagtcg acgccgccgg gtttttgttt cgcggtcaaa
    32161 gccagccgct acctcaccca tcagaaaaaa ctgctcgatc cttcgcctgc gctgaaacga
    32221 ttgctgggtg cggcagtgca tctcggtgca aagttgggcc cgattctgtt tcaattgcct
    32281 ccccattggc gatgcaacct cgaacggttg agcgactttc tgcgcacgct gccgccttcg
    32341 caccggtata gcctcgaatg ccggaatgcg acctggcaca cgggcgaggt ctaccgtctt
    32401 ctggaacaac acaatgtggc cttttgcctc ttcgaactcg gtggatgcat gactcccatc
    32461 gaggtgacgg cggatttcgt ctacgtgcgg ctccacgggc ctggcaataa atatcaaggc
    32521 gattatccca cggcgacgct aaaagcctgg tgccgtcgca tccggcaatg gacccgttgc
    32581 gacaaggatg tgtatgtgta tttcgataac gaccaggccg gttatgcgat caagaacgcg
    32641 atgtctctgc gggcgatggt cgatggttct taattgagtg attgctgagg cgagcgattg
    32701 gcggacgtga aatattggtc gctagggcga aactggacga cgggttgccg cgtcgggcgt
    32761 gcccggattg gtcttcatcc cctcataggt gctgcgttca tcttccagtc gcacctgtcc
    32821 atagatcaag tagccattgt atgcgcgcgc ggtttctctg gcccagccca tggtcaacat
    32881 catgagcatg gcgcataggg ctaacgtgat caggagcgcg ggactcgacg actctttctc
    32941 tgagccgctc tgaccctgcc accatggaac tcgattggca taggatcgga agaaaaagag
    33001 ccaattcatg aggccgaaga ccacaagaaa cgcgagggcg aaatatttgt tcggttgcat
    33061 ctttcccaag gggttgatga ggcggtcggt gaggatctgc atccccggga tgtgttgcag
    33121 ttggtagggt tgggaaagaa tcatacccgc aattgcaacg ataagcagcg acatcggcag
    33181 tgccagcctg gctgttcctc cctcgtcatt cgctggctgg gcccgtacgc tccgccagat
    33241 gtaccaggat ccgaacagga cgaggagtga gtagagggtt gcgacgagat cgaagagcca
    33301 ggagcgggcg ccgagcatca gcgtgtaaaa cgcctgcggt tcgatgtggc ggactctgag
    33361 cagatattgg tacccgatgg ccggcatgat gagcagggcg ccgaagccga tgatgaagca
    33421 gacccctcct gcccaccggt aaaacgcgcg atcgtcttcg cctcccgaac gtagaaatcc
    33481 cgccgcgcag aggcccgcga gaccgaatcc ggtccaggtc agattgccca cgatccgatg
    33541 cgtgtccaga tagagcatgg tgggattgaa cagtttcgcc caggtgtcgt cgggtgggcg
    33601 gggagtcaac atataggaag cgaccatgtc gatcatcaac atcgcgatga gggaagaggc
    33661 ggcggcggac cacccgaaga caaggtgcca gcgtttgcgc gccggctgct ggttcgccca
    33721 atcccaggag taataccagg tgtaggcaaa gatggcctcc gccagaaaga atgatgcttc
    33781 gagcagaagg ggccagaaca taatatgaaa caactgactc cagaatcggg gccagaagat
    33841 gttcaagagg aagacgaatg tcacaccgag aaaggagatt ccggcggtcg tgagaatgag
    33901 tgtgaaggca atcaggcggg agagccgttc gaagcgaagg ttctgcgtga catgcccgat
    33961 ggtttccgtc gccgagccga tcaccgagga gccgacgatg aaggtcgcgc agagcgcatg
    34021 ggccaaagct gcgactgcta tagccacccg tccgtagagc atgggaatct ggagcgcctc
    34081 catctccatc agcggagcgc tccttccatg cgtgcctgat gccgcaattc gtcctgaagc
    34141 gaaattatgc cgcggacggt gtccggtcgn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    34201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    34261 nnnnnnnnnc ctgatgccgc aattcgtcct gaagcgaaat tatgccgcgg acggtgtccg
    34321 gtcgccggga ggcttctctc atgacaccca tggtgaggta cagcagaaag gataagagag
    34381 ccaggccgac ggccagtgag cgcaccggtg acggagagag agccgattct gtgggtgcct
    34441 tggacacgga ggcggccact cgccataccg tcacgccgac gagcaggtat acacagaccc
    34501 ggcggagttc cgggtagccg gcagagagta ggagtagcgc tgccagaaca ggaaagccga
    34561 tgtctagcca gcgttgtctg ttgccagtca gcgtccgcat gcgtttcgtc aagacatcat
    34621 tgccgaggaa gaacagagag aggaggagca attggagata gagccatggc acgtatgggc
    34681 cggtcatgat ggatgcctgg gcgtccggtg ctgcgcgatg gatcgccatc gcatacagca
    34741 ggcccgtgaa gggctgcaac aggaacgcga ccaatccgat cacccagcct ctggagagca
    34801 gatgttggta gtaaggcttg agagcaggct cgccggggct ccaaactcgc caggcgccgt
    34861 aggcggcaag ggtatatcct gcgatcatca gatttccgac catccggtgg atgacgagcg
    34921 gcagccaggt gggagtgaag agtcgttccc acgtccctcc ctcctgcacc ggcgtcagca
    34981 tgaaggcacc catgccgtcc agcatgaaga cccacggcag catgaagaaa gcggccaagg
    35041 ctcccagaac catgtggagc gtgatactgg ttgctcgtaa gcggtcccag aaatggtagt
    35101 agggatacag ggccagcagc atcagcatga acgaggcgac gccgaataga atcgggacgc
    35161 gaaagtgatt ccacatccac atcgtggtga ccgggaagag accgatcatc agttccacca
    35221 tgatgacggc gagcacggtg ctgacactga acaccaccac ggtgactcgt gtcacaagaa
    35281 gcgccagctc tcgatcaaag ggatccgtcc gccctctgaa ttcaaaaacg ggcgccatca
    35341 acataaaggc cacggaaagc gcggctggaa cgatatgcag caggctgaac aagcccaccg
    35401 cgacgctatt tcccagaaga ggaatctgaa tggcaggcag caccgttcca taattaatca
    35461 tgtgaccgtc gttcctcgtg agccatggtg gtgtctggct ccatggcatg gacgaatgac
    35521 gccagaatca tgcgctcggt ggcggacagc tcgccttgaa aggaaggcat catgtccttc
    35581 ccctgcgtaa tgatccggta gagttctgtt ttggacagag ctcgcactcg aggtgaccgc
    35641 aggtttgccg gcagttcgtg caaatagggc gcgacaaggc ccgttccttc tccgccctcg
    35701 ccatggcagg gcaggcaatt gatgcgatac agctcagggg cgcgccctcc ttccagctcc
    35761 atggtgcgag cttcccggga caaaatggcg cgactgtcgc gagggacgct tcccgtcgga
    35821 gaatggaggc gcggggcttc ctggcttcga taggacggct gttcctgcat atccggggaa
    35881 cagcccccca cggtgataca gatcagaagc catgcggccg tcacatgagc ccgttgcatc
    35941 ccttgttgaa tcggcgaagg gtgagtcacc agccgaacgt cctccgcgcc tgccatttcg
    36001 agcaacgttt tgacgcgctg ttcctggccg tcttcgacga gacgcactga gagcgcaatc
    36061 tttccgtcat cgatcctggt ctcacgatca acggaggctc gccgtgcccg tctgatcctg
    36121 acgatcatcg tgataaacgt gacgacgatc gccaacaaca tcatcgtttc ataggaaatg
    36181 atgccgacga tgggagcgga cacaatcggt ttgcctccgg tcatcaaggg atacaggagc
    36241 gcagtgccgg cggcgaagaa gactcctacg cctatgccca caagcccggc gacgatcgtg
    36301 atgatgtaag gccacaaggg ctggctggta ccatctgttg cggaagccga cttcaacggc
    36361 accggggtca ggagtgcgat ctgatcctgg gagatgccgg atccctccag cgacaggcgc
    36421 acagaatcga gatcggcatc aagcggaaag agtgcgatca ggccttcgca aggctgagtc
    36481 ctgctcatgc aaccgtcctt ccttttcttc ccagatggaa atgatcggaa cgaacttgat
    36541 cgccagcacg tagaggagca ccgccagcga aagggaaccg gccatgattg tcagttcaac
    36601 ccacgacgga aaatagtcgc tccaattgta ggtcaaccgg ggatgggcca acggcggggt
    36661 gagaatcagc atccgctcga tgtacatgcc gatattgatg cagaggccga tcaccagcat
    36721 gccggccggc cacgtgcgga aggcgggtat tgttaaggtg atcagcggca gtacatagat
    36781 caacgtgatc atggtccatt gaggaacggc atagggtccg ctcatgactg catgcatgac
    36841 cgacagatga tccggtatcg ctccgtacca gaccgtcagc tggtctgcga aatagaggta
    36901 ggccagcgtc agcgtcatca cgatcatgag cttgccgagt ttgtcgaaat gttccaggcg
    36961 aatgtaagcg tcgagtcgat agattcgccg cacgaggtac aaaccgatga cgaccatgcc
    37021 cagtcctgaa tgcaccgcgc ccaccacgaa gtagggggcg atgatcgacg tgtgccatcc
    37081 ggggaccagc gacatgccga agtcccagcc gacaatcgaa tgtaccgaga tcatgaccat
    37141 cacaatcagg ggagtgatga tcctgatcgc agtgttcagc gccgtccatt ccctctggga
    37201 acctcgccag ccgaggctga gtaaggaata gagcggcttg cgccatccgc cgatgcgatc
    37261 gcgaaccaat gcaaaatccg gaatcagcgg aaggtacaga tagatggtgc tcgcggtggc
    37321 ataggtaaag acggcggtgg catcccacat gagcggagaa cggaagtccg gccagatttc
    37381 acgctggttg ggatagggaa tcaggtaata ccaacgccag gatcttccca ggtgataaaa
    37441 gacgaacagg gtcgcaatga ccacagagat gatcgtcatc aactcggcga ccctcgtaat
    37501 cgggcgtcgc cattccgcct tggtcagtcg aagcaccccg gagataaagg tgccggaatg
    37561 gctgacgccg atccaataga cgaaggaggc aatgtaggca ctccagaaga tgggaggatg
    37621 caggttcgtc cggccgatgc cggtttcgat ttgatagacc caggctccaa tgccggcgga
    37681 taccatggcg gccagcaatg tgaccaggag cacatacccg cggcctcccg ctgaaagggg
    37741 cgccaacagg tctcgattga tggccggcat ctcttcccag ccggctgtgc tgtggttcat
    37801 tcatccaacc gtttcaaata ggtaatggcc ggatgcgttc cgagcgattc cagcaggtgg
    37861 aagccccgtc cgcttttggc catggtcgca acccggcttg tagggtcatt gccgtcgccg
    37921 aataccaacg cggtggtcgg gcaggattga gcgcaagcgg gggtgatatc gccatcgcgc
    37981 accgggcgac cgtcgcgctc cgcctgttcc ttaccctgtc tgattcgctg cacgcagaac
    38041 gtgcattttt ccatgatgcc gttttgccgg accgtcacgt cgggattgag ttgctgttcc
    38101 aacggtggat cccagtgggg atcgaaccag ttgaattgcc gcgccgtata cggacaatta
    38161 ttgccgcagt agcgcacccc gatgcatcgg ttatagacct gggcgttgag gccctcaggg
    38221 gtgtgatacg acgcgtagac cggacagacc ggctcacaag gcgcatcggc gcagtgttgg
    38281 cagagcacgg gcatgaacct cgctttgacg tcgggatatg cgccttccca atagcgttcg
    38341 atgcggatcc aattgatggc gcggccgtcg gacgcttctc cggggccgga aatgcggata
    38401 ttattttcag catggcaggc gacgacgcag gcctcgcagc cggtgcatcg atccaggtcg
    38461 atcaccatct gccaccggta agggcggggt tcatctgatg gcctctgctt gtcttccatg
    38521 cttcagtcct ttcgtcgaaa cctccggttc acccagtgaa ggccgtccga ctcatgtgcg
    38581 ggccttggat gagggcggcc gctctatcga gatcaggtca gagcttccag ccgcggtcgt
    38641 gcccggcttc tcaagaagga tcaaagtccc cggaacgttc aacggttcag cccggaccct
    38701 tgtcgcaccg atggccaagg cccccgattg cttgtcgaat aggggcgcga gaatcgtcat
    38761 gggattggct ccccgccgag cggcatatcg accatagtcc gtatggcctt ggccgatggg
    38821 catcgcgatg acgtcgggcc gcagcccggg atagtgcagg gcaggtgcct cgagagatcc
    38881 atggcgagag tgaaggcgca cgagtgcacc ctgctgaatc cccatggcct gcgccgtggc
    38941 cggattgatt tcaatccaac ttccccacac tgcgctggtc atggtatcgg gcaattcctg
    39001 gagccacggc agattggcgc cgcgtccctg ccccagatgc ggcgcggcga aggggtatag
    39061 gtagaaggga aactcggagg catcaccgtc aaactctggc gggcgatact ccacagcgga
    39121 agacgactgc tgcaagcgtt gttcgttggc cgccgagtcc caccagcctc cctgttgaag
    39181 gagttgttcc cagactgatt gaaacggttc atgggagccg gacgagtggg acgtatgaaa
    39241 gtgctgccag cgtttcttga tgtgctcagg aaacgactcg accccggcgt gcttgcctgc
    39301 caattgacgt gtcaactcaa gcagcgtgtc gcccaacccg cgcgtgtcat acagcggcac
    39361 cacaaccggc tgcaccagac tcgccgcacg gtacggtgag gacccgccct gaacatggtc
    39421 gccccaggtt tccaaccgat gatggtctgg cagaatcaga tccgcactga cggtggactc
    39481 atcgaggctg ccgctgaaac tggcaatgta ggaagcgcgg tcaaatagac gtcgaatagg
    39541 gatggcaggt ggaacgctga acaagggatt acagtcatag agcaacaaga gcgggcgttg
    39601 cccggtcttc tcgatggtct ccgccagttc cttgatgcgg cgttctgaca gccaggggat
    39661 ctcgggatga agggtaagtg aggccgactg ataccagcgg atgcctcccg ctttgttgat
    39721 gtttcctgct aaggcattga gcccgtgaat ggccaggtgg gtttcgaacg cgttcgtatg
    39781 ggcacaagca gtgccgccgc cgattgcctg gggagagtcc gcctcagcaa atgctcttgc
    39841 aacccttttg atgtcagctg tggaaatgtc cgtctgcttc gccacctcgt ccagagagag
    39901 acggccatac aacgattcgt atgcatggag tcgacccgtg ggcagactgg aacggtgttc
    39961 cgaaagcagg atatgaccga taccgcgcgc gagaagccct tccatgccgg gccggatggg
    40021 cagccaacga tctgcgctgg cggccgtcag agacaggcga ggttcgacgt gaacgaaacg
    40081 cccgcgtcga ttcttgcgtc cctgtcgcat ccggccgaac gcgataccga acgacaccgg
    40141 cgacagccac tgttccagaa acggtgcgcc gaatgacaac acatagtccg catcgcccag
    40201 gtcataagca ggaaggtcgt gaatgtcgaa tgcctgtttc atcgccgctc gcagagccaa
    40261 ttcaggcgac ggatcataga agtacaagga gccctttacg gaagcgacaa agtccgagac
    40321 gacgtctgcc agcgtgccgg agagcggccg gctgatcatg atgaccgggc ccttcgcgtg
    40381 gcgtatctgg tctgccagtt gatgaagacc ctcatcccac gaaaccggcg taaatcgttg
    40441 atccgcttcc gtgcccattc ggcggagggg accccggagg cggtcagggt tgtaaaggcg
    40501 ttgaagcgct gcctgtccct gcgcacagag cttcccctgg ttgaccggat gcaaaggatt
    40561 gccttcgatt ttttttgcgc ggccttccat taccttcacg atgatgccgc agccggcgtc
    40621 gcattctccg caggtcgagg cataccactc ggccacaccc ggaatgattt cgtcgtccgg
    40681 gagcacgtac ggcaccaatc ggcgaacctc ttggtcgcac ccgggaagaa gtgtcccagc
    40741 tgccgtcagc cccagtgctt tgataaacgt tcgccgtttg acatccattc gaacaccgtt
    40801 atctgcatga ccaacgcggg gcagccgatc atttgtggca ggtcacgcaa tcgcgtgaag
    40861 ccccacgttg ctgatgacac gagaggcacc agcccatttc atacgttgcc gcgcgtggtg
    40921 tgctcgtcat acgcgtcacg tcgccatggc atgtggtgca ttcgaggccc tgggccagat
    40981 gacgttcatg ggtgaaatag acaaaatccg gcagacgttg cagtcgcacc cactccaccg
    41041 gtgcttgccg cttccaatga tcgaccaatg tctggatgcc tgctgtcgcg acatccaggt
    41101 tttggtgaca acccatgcac agctggaggc ttggaatccc ggccgccgga gagatatgcg
    41161 cggccctgtg gcagtaccgg cagtcaaggg cgagttcgcc ggcgtggaag gcatgattga
    41221 atgcaatggg ctgttggtcg tgggcggcgg agtcagcgct gcctttcgag tacagaatcc
    41281 caatggccag cgcgctgaca gtggccagcg agaccagacc aagactttgc cacaatgaac
    41341 gtgtcatcgg acggcaagga acattctcgt agcgcgttcc aactcgttgt tgtctcatct
    41401 attcagaggc tgagagacgg ttctactagg cattcctcct gagcccgcgt cgaataacta
    41461 ccgaagcctc tctgctaggg aaccctctag ctcaaagcct cgtccgccag agctacagtg
    41521 ggtggacacg tctcgacggt atgagaaccg tcgaaggctc gaatctttca cgaacttcac
    41581 acggtctaaa gatgcctcca cggactagag atgcggaacg acgtgtgatg gagcgagatg
    41641 tctgctcgac caatggcgac tccggcccga aaatcgaaaa ggttcaggtc tctgcctaca
    41701 caattcccac ggccggcccg gagagcgatg gcacactcga gtgggatcgg acgacgctgg
    41761 tgctcgtcga tgtgagcgca gggggccagc acggcatcgg ttatacctat gccgatgtct
    41821 cgaccgcgtg gtttgtgaag cagaacctgg cgcctgtcgt cgagggtcgt gatgcgatgc
    41881 acatcgcgga cgcctggtgg gccatgatgc gctcagtgcg gaatctcggc catccgggag
    41941 tggcttcaat ggccatcgca gcggtggaca ccgccttatg ggacgtgaaa gcacggctgc
    42001 tcgatcttcc gttggtgtcg ctgctgggcc gcgtccggac agcggtgccg gtctatggga
    42061 gcggtgggtt cacctcttat tcgatcgatc ggttggaaga gcagctaggt gggtgggtca
    42121 gggacggcat ttcacgcgtc aaaatgaaag tcggccgtca accggatcag gatcttcgcc
    42181 gggtggaggc tgtgcggaag acgatcggag aggaggcaca actgtttgtc gacgccaacg
    42241 gcggctacgg ccggaaacag gcattgcagc tgtccgaagg ctttgccaag gccggggtcg
    42301 tatggtttga agagccggtc tcgtcggacg acacggaggg gctgcgctta cttcgtgata
    42361 gggtgccggc gccgatccag gtgacggcag gggaatacgg atacgatctc ttctattttc
    42421 gccgcctgct cgatgcggag gccgtcgacg tgctgcaagc ggatgccagc cgctgcggag
    42481 gcatcacggg attcctcaaa gtcgggtcgc tctgcgaggc acgcccagtc ccactctcgg
    42541 ctcactgcgc cccgtctctg catgtccatc ccggctgtgc gtcgatgtcg gtgtgccaca
    42601 tcgaatactt ttatgatcac gttcggatcg agcagctgtt gctcgatggc gcgatacgcc
    42661 ctgtcggcgg ggctctctat ccggatctct ctcgtccggg aatcggattg gacttcaaat
    42721 atcaggatgc tcgccggtat caggtgtgac atgcgtgagc ccctcattca cattcagtcc
    42781 gccggtcagg attcaactca aggggcttcg tatgcggcgg aaccgagtga tgcgatgcgg
    42841 gaacacctgg cgcggcgcat cgatgcacag ggattggccg aggcgctgcg aaagaacatc
    42901 gatggcgaag tccggtttga tgaaggcagt cgtgccctct atgcgacgga cgcatccaat
    42961 tatcggcagg tgccgattgg ggtggtgatt ccccgccatg ctgacgacgt tctgcggacc
    43021 attgccaccg cccgaacgta tgacgcaccg atcctcgcgc gaggtggcgg gacaagcctg
    43081 gccggacaat gctgcaatta cgccgtcgtg cttgattgtt ccaagtatat gcatcggctg
    43141 gtcggcatcg atgtcgcggg tcgatcggct cgcgtgcaac cgggcctcgt tctcgatgat
    43201 cttcgccatg cggccgaaca acaccatttg accttcgggc cggatccctc cactcacaac
    43261 cattgcaccc tcgggggaat gatcggaaat aattcctgcg gcgttcattc ggtcatggcc
    43321 ggtgagacca gcgagaatgt gatcgaaatg gacgtggcga cctatgacgg gctccgtctg
    43381 cgagtggggc gaacgtcgga tcatcagctc gatgaaatta tcgctcacgg tggacgggag
    43441 gcggatctgt accggcgcct catcgctctg cgtgaccggt acgccgacct gattagatcg
    43501 cgcttcccga atattccccg ccgggtttcc ggatacaacc ttcccgcgct gctgcccgag
    43561 catgggttcg atgtggccaa agcattggtg gggtcagaaa gtacctgcgt gacagtgttg
    43621 gaggccacgg tgcggctggt ttccagtccg cgtgtacgtt ccttgctggt actgggttat
    43681 ccggacgtgt atgccgccgg tgatcatatc cccgatattc tccgcgcgaa gccgatcggc
    43741 cttgaaggaa tggacgatcg gctcgtggag gacatgacca aaatgaaaat tcacccggac
    43801 gacgtcaagt tgctgcctga agggcggggc tggctgcttg cggagttcgg cggtgagagc
    43861 aaggacgagg cggatgggca ggcgcatcgc tgtatggaac tcctcaaggc cgccggacac
    43921 cccccctcca tgaagttgtt tgatcgacgg cgagacgagc aggtcatctg gacggtccgt
    43981 gaatcagggc ttggagcgac ggcccatgtg cctggagaac aggtgacctg ggaagggtgg
    44041 gaggattcgg ctgtccctgt cgagcgcttg ggcgattacc tgagggcctt gcgccgtctg
    44101 ttcgagaagt atcgctatgc ctgtgcgctg tacggacatt tcgggcaagg ctgcgtacat
    44161 acgagaatcg attttgatct gcagacccag gaagggatca gccggttccg gtcgtttctg
    44221 ttcgaggcgg ccgatctcgt caagagtttc ggcggttccc tttcaggaga acatggtgac
    44281 ggccaatcgc gcgccgagtt actcccgcga atgttcggac cggaactcat aggggcgttt
    44341 gaagaattca aggcaatctg ggatcccgat ggaaagatga atccgggcaa gatcgtccgg
    44401 cctttccgtg tcgatgaaaa cctgagactg gggagcgact accacccgcc ggatcctcag
    44461 actgatttta cctttccgca ggatgaatat agtttttcac gagcgacgct tcgttgcgtg
    44521 ggggtgggtg aatgtcgccg gcaggcaggg ggcaccatgt gcccgagtta ccgcgcgacg
    44581 cgtgaggaac tccactcgac tcgcgggcgg gcacgcctgt tgtttgaaat gctggaaggc
    44641 gatcccctca cgcgcggctg gcggaatgat acggtgaaag aagcgctcag cctctgcctg
    44701 gcctgcaagg ggtgcaaggg ggattgcccc gtccatgtcg acatggcgac ctacaaggcc
    44761 gagtttctcg cccattatta caaagggcgg ttgcgtcctc gatcggccta ttccatggga
    44821 ttgatccacc ggtgggctag atgggcttcg cgggcgcccg gcatggccaa tttcatcacc
    44881 cagacgcctg gattgtgcga cgtcgtcaaa atgctggggg gtatttcgcc ccaccgcaga
    44941 atgcctcgct ttgcagccga gacgtttcag gcatggcatc gtcagcgcgc gaaacgagca
    45001 ggcggtgggc aaccggtact tctttggccg gacacgttca acaattattt ttacccggag
    45061 acagccaggg ctgcgaccga ggtgctggag gctgccggat gtgccgtgtt cgtgccgcag
    45121 accaatctct gttgcggtcg accgctgtat gacttcggca tgctgcggca agccaagcga
    45181 cacttgcagc agatcttgtg tgaattagcg tccacgatcc gtagcggtat gccgttggtg
    45241 gtgctggagc ccagttgtgc tgccgttttt cgagacgagt tgggcaacct cttccctcat
    45301 gacgaggatg ccagacgcct ggcgaaacaa accttcacgc tggcggaatt tatcgacaaa
    45361 cgtttgccgg actgggaact acctcaatcg catcaatccg tgacggtgca tggccattgt
    45421 caccaaaagg ccgtgatcgg gctgggtgca gaagaacgcg tactggatcg attggggctg
    45481 aatgtgcaga tgctggatac cgggtgctgc ggcatggccg gctcctttgg tttcaaacag
    45541 gagcactacg atatttccat gcagattgga gaattggcct tgctcccagc gatcagaaat
    45601 accgctacag atacgattgt gatctcggat ggcttcagct gcagacaaca gatcgagcaa
    45661 tcgacgcacc ggcaggggat gcatttggct gaagtgattc atcaggcaat gggcaacgta
    45721 acaatgcacg tgtcggcctc ggctcacggt gggacttaac catgaatcag gggccgtgcc
    45781 gatacagagt ggaagtgatt gctcgatgan nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    45841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    45901 nnnnnnnnnc ttaaccatga atcaggggcc gtgccgatac agagtggaag tgattgctcg
    45961 atgacgtcct cgaagacatt gatcgcggtg gtgctcattt gcctgatcgg gacgggtatg
    46021 ctgaatagcc ggccggtttt aggcgaatgg tatgtcgccg gtcagttcgg agctaatttt
    46081 gccgatcaac tgagtgacat tcacggaacc ggcaatctca gcggctttcg cgcgccggat
    46141 tttgatttgc agaactcgct gctgtatgga gcaaaggtcg ggaactttcc gggaaacgga
    46201 tggttcggtc tggagctaga cgtctttcac agtacgccgc acgtcaagaa cctcgatgat
    46261 gtgccgggct ttcacatgcg ggtgacgaac gtcggcgtca atctgctggc tcgataccct
    46321 ggagtgacct tccagcccta tgctggaatc ggcgcgggag tggccatcgc gcgaatcggc
    46381 gattcggcta cgaccagagg cagtaccgat gcatcttcgg cgttgaattt actggtcggg
    46441 atcagggcat tcgtgacgcc atatgtggcc ctgtttaccg aatacaaata cagccaatcc
    46501 acctttgaat tcagtcacgc gttcggccct tcgagtgggt ttaatggaaa ttatgatgcc
    46561 cacatcttgg ttaccggctt gtcataccat ttttaagaaa cgctattggg ccacagcagc
    46621 gctcttcctg tctgcgtggc ttctcagcgg gtgcgcgcaa agtgcgcatc agtccgggcg
    46681 cgatctgctg gatcagattc tgccggatca gctgcagcaa cagattgatc ccactgtcac
    46741 gtttccagag ctgaaagcca atccttccgc ctatcagggc aaaacgatca tggtcagtgg
    46801 cattgtggtg aagagtaagc ggaggaagga tcagacggag attgaggtct tgcagatccc
    46861 gacaggaacc ggggctgtgc ccagcaagga tcgtgcgcac tctcagggaa gatttcttgc
    46921 cgtaaagagc ggtgaatttc tcgacccagc cgtagtcgac gcagggacgc cggtgacggt
    46981 cgtcggtgaa gtgggaccgc cggtcaccag gccgatggac gacggggaat acacctatcc
    47041 cgttctcgcc atcacacatc tcgttgattg ggatgaagtt aatccagcta tgcgttccgc
    47101 cccgtatgcc tatccgtatg gacgctcgat gtatgcctat ccctatgcct attgggggcc
    47161 ggggggctgg tacgggggct atcctgggta tgggtacgga tatccctatt acggtttcta
    47221 tggcttcggt ggaggatcat ccgcgccggc cggcccgcca ccggcagatg ctcctccgca
    47281 gttcaataag tgatggggca atcgaccatc ccttcgcagg agtgacatga gtcttcgtca
    47341 atactggaag aaacgaaact tccgcaacac tcccgagccg cgaggaaaag aaacgccggc
    47401 gggagcccgg ctccagtttg tcattcaaca acacgccgca agccggctcc attacgactt
    47461 tcgcctggag ttggatggca cattgaaaag ttgggcggtt cccaaagggc cgagtctgga
    47521 tccggcacag aagcggctgg cggtccatgt cgaggaccat ccactggact atgcgtcctt
    47581 cgaaggcatc attccggaga aacagtatgg cgcgggcacg gtgttgctct gggatcgggg
    47641 ctactgggaa ccgatcggtg atccgaaagc agactatcgg cgaggccgac tcaaattcac
    47701 cttacacggg gtaaagctgc aggggatctg gaatctggta cgcatgggcg gccgcgaaga
    47761 ggcagggaaa gagaattggc tgctgataaa agagaaggac gctgaagcca agcgcgggac
    47821 gcagagccgg gtgactgacc gtttgacgag tagcgtcgcc agcggcagga gtatggagca
    47881 aattgccacc ggagagcatg cggtgtggca ttcgaaccgg tcctcgacca catcggcaaa
    47941 gaaacgtgcc gtctcccgcc cggtagagaa aactcctgcg gccggcgccc ggaaggccgc
    48001 acaggaagag tggatcgttc cacaattggc gacattggtg actgcttctc cggaagggga
    48061 agactgggtt cacgaactca aatatgacgg atacagaata ttgtgccgcc tgaaagacgg
    48121 tcaggtgagg ctcctgacga gaaacggcca tgactggacc gcgaagctgc ctcatatcgc
    48181 cgcagcacta acagatttgc ccgcacaggc ggcctggttc gacggcgagg tcgtggcgtt
    48241 gtcgccggat ggtcgcatca gcttccagct attgcagaat gcgttcgatg cgcactcaga
    48301 cagtgatctg ctctattacg tgttcgacct gctctatctg aatggctacg atctgcggga
    48361 ggtgccgctc ctggagcgca agcggcttct gtcggctcta ctgaaagacc gaccgtcgtc
    48421 ttccttgatt cagtacagcg atcatattac cggcaggggc gacgtcgcat tcgccgaggc
    48481 ctgccggagc gggatggagg gattgatcgc caaacgagcc gatgctccgt atctttcggg
    48541 cagaaaccgc aattgggtca aggttaaatg cgggcagcgg caggaattcg tgatcggagg
    48601 atttactgac ccctccggtt cacggagcgc cttcggtgcc ctgcttcttg gtgtttatga
    48661 tgcgcagggg cggctgcaat tttccggacg cactgggacg ggatttacgg agcgctccct
    48721 caaggaatta cacacgcgct tgaagaagat cgagcagaaa cagccggcat tcgtgaatcc
    48781 gccggtcggc agtgaggcgc gtggtgtgca ttgggtcaaa cctctcctgg ttgctgaagt
    48841 agcctttgcc gaatggacca acgaggggca gctgcgccag gcttcatttc aaggtgtacg
    48901 agaagacaaa gacgcccgtt ccatcattca tgaacgacct gactcaggcc cttcttctcc
    48961 gaaggcacgc aaggggcggg gacatgctcg ctcgcgccgg atctcatcaa atcagcagac
    49021 tccttctgcc ggtgccgaag cggatgaaac cgcgccggtc attggcggtg tcacgctcag
    49081 tcacccggat cgggtgttgt ttcccgagca aggcatcaca aaaattgcgc tggctcggta
    49141 ttacgagtcc atcagcgatt ggattctgcc gcatgtcgaa ggtcggccgt tgaccctggt
    49201 ccgctgtccg gaggggcaca agaaggagtg cttttatcag aagcacgcag gggagcacat
    49261 acccgacact gtgggccggg tcgagatccc ggaagaaaaa ggctcgtcct ggtacatggt
    49321 ggcggatgat cttcccgcgc tgattgggct ggtgcagatg gggatattgg aacttcatac
    49381 ctggggggca aagcgagacc agctcgaacg gccggaccgg atgattctgg atcttgatcc
    49441 cgatcctgcg gtcgaatggc cattggtgat tgaaggtgcg caattgctgc gcaccttgct
    49501 cgaggagctg gacctcgtct cattcgtgaa gacgacagga ggcaaggggc tgcatgtcgt
    49561 cgtcccgttg caacgcgccc atacgtggga tgaggtaaag accttctcca aagccgtggc
    49621 tgatcatctc gtccgcgcga ttccggaacg atttctcgcc aacatgtcga aacagaaacg
    49681 caagggcaag atctacgtcg actacttgcg taacgcccga ggggccacgg cggtggccgc
    49741 ctattcaact cgcgcgcggc ctcgcgcgcc cgtctcggtt ccgctcgcct ggaatgaatt
    49801 gtcgaccgat ctccgttctg accatttcac agtcgacaat attgccgaaa gactcgagca
    49861 tttgcgacag gatccatgga agacctactt caccacgagg caacgtatta cgaagaatat
    49921 ggtgcgccgg ctggcaggat aatgtcgaag ttccgccagg gtgctttgct aggggacctg
    49981 gggggagtgc tagtagagtg aatcgtacgg gactgttatc agtgatcatg acaatcggtg
    50041 gaagacattc cgccgaagcc tatcaggatc acgacgaaag gagaaccgta tgaatgccac
    50101 cacgacgaga acccttcctc tcacgggcaa aaccagatct actcctgctg tttcccaaca
    50161 cgatacctgc cgatgcctcc gctgcggcgg attcctggtc gatgaacgct gtatggatat
    50221 cggggagagc cttggtggtt actggtttat ggcgatgcgt tgcgtacagt gtggcgacat
    50281 caccgatgaa gtcattttgc ggaaccggtc tgcgcaactg gcgacgacga ctcagcacga
    50341 ggtggtgaga gccgcctgac ggtcaatcgg tagagggttc cctggaagag tagttgcttc
    50401 ttgaagtctg ggcgagaacg ggtttcgcac gttcctgtgc ggggcggctc agacaggaaa
    50461 ggccatcgtg ctgaagagcg cattttcagc ctgccgggaa tccagcctgg tatgttgcac
    50521 gacgatgcgg acgttggaat cgatcaggct ggagaaatcc gtatccagag gaatcggggc
    50581 tggatcagtc aaatcgttaa agcggacgtg ttttgttcgg cgggcgggaa cctgaataat
    50641 atagggaccg accggttcgc gatccgcata aaaaatcgtg acctgcacgg tcgcatcctg
    50701 gtccgaagag ttgaggatgc acatggtttc gtggctcgtc atttgtggtt ccggcccgtg
    50761 gcttttggat ggaatatatc cttccgcaat cacccatctt cggcggccga tcggctccat
    50821 aggctctccc cgttaagtgc cagtacacgc ggttgcttca caccacttct ctgattttgc
    50881 tctcgaccaa cgttttgatg atgccccatc ggtcatcctg ccctttggct aaggccttcg
    50941 caaactgcca ggcttgcgtc gtcgtaattt tcccgggtag cggtggttcc aacggatcaa
    51001 tgaccgcctg gaccacggcc ggcccttgaa cggcgaaggc ctctcgcagc acctcacgga
    51061 cgtcgcccgg atcgtcaacc gtcaatcccg tggcgccaca ggccttcgca aagagcgcaa
    51121 agtcgatcgg ttgaagatcg acgccatatt gcggattgcc ctcgaacgcc agctgttccc
    51181 acttgatcat gccgagcaga ttatttttca ggacaatgat tttaaccggc aggccatacc
    51241 tcaccagcgt ggccagttcg cccatcaaca tcgtgcagcc accgtctccc gcgaggcaga
    51301 cgatctgtcg gccaggatac gcaatacccg ctcccagact ataggggagc ccattgccca
    51361 tcgacgcgag tgtgccggat gctgaaaatt ccatgttctc cctgatgatg atgtgccggg
    51421 cagcccaggt ggtcaccgtg cctgtgtcgc aacagatgat ggcgtcgtcg gcgaggaact
    51481 cgttgaggcc tcgcaccacg acttgtggtt taagaggagt atccgttctg gtgcctcgct
    51541 cctccatgag ctcattccac tgctgcatgc tggcttgcgc ggtgttgaga aagctgcgat
    51601 ccgatttctt ctccagcagc ggcaataacg cgcgaaggac atcccaacaa tgtccgacga
    51661 gaccgacctc gatcggatac cgcaagccga tgcgagcggc atccaaatca atctgaacgg
    51721 ctcgcgcttg gcccggtttc ggataaaact ccagatacgg aaagctggtg ccggcgatga
    51781 tgagggtatc gcaggcttca aggacttcct gagagggcgc cgtaccgagg agcccaatgc
    51841 cgccggtggt caatgggtgg tcgtccggca ccacggcctt cccaaggagc ggcttgacga
    51901 tcggcgcgcc cagcaattca gccagctgca gcacttcggc tctcgcgcct aagcagcccc
    51961 gtcctgcgag gatggcgatt ttcgagccgg cattgatgag cgttgcggcc ttctcgagca
    52021 gtgatcggga ggggaggggg agggggtcgc tgtacaggtc tccgctatgg ccgggaatgt
    52081 tggccttgga tccgcgatct tcgacgctcc agtcctgaat atcttttggg atggtgatat
    52141 gggccacggt ccgtcgtgaa atggccgttt tgatcgcctc gtccaccaca ttaccgacat
    52201 gagccgggct catgaccctc tggctatagg cggcgacatc cgagcagagc cgctccagat
    52261 cgacatcctg ttgatagtgc gtgccgatca gatcgtggta cgtatgcccc gtgatggcga
    52321 gcaccggctg tccgtcacat ttcgcatcgt acaacccgtt cagaaggtgg atacctcccg
    52381 gtccggaggt tgcgagacac acgcctaatc gtctggtgaa cttggcatac ccgcaggccg
    52441 cgaaagcggc cgattcttca tgccggacca acaccaccct gattttgtcc tggcgggttc
    52501 gcaaggcctc atagatgccg ttgatgccat cgccggggag actgaagatg gtatcgactc
    52561 cccattgaat caagcgttcg accaagagat cagccaccgt ggttgccatc gtcgttcctt
    52621 tcacggatca aaaagaagga ggcgggctcg cggcgttgtg ttccaaccgc ggtagcacca
    52681 attcctggac gaggattttg agacatgcgg caatgggaat cgccagaagc agaccgtaaa
    52741 atccacccag tgctccgccg ataaacacca cgatcagcac ggtcaccgcg ttcatttcca
    52801 tggattggct ttgcacccag ggcgtcagca accaactttc gataaactgc accacgaggt
    52861 aggccacaga cggccacacc accaccgtca tgacatcgaa ggagccagcg ccggcggaaa
    52921 acccgtccag atatttcaac agcacggcca atggccagcc gattaatgat gcatagggaa
    52981 tgatcgtgag aatgccggtg atcaggccga ggataaacca atagcggatg ccggtcagcg
    53041 cccatccgac cgagtagagg acggcagagg cgagggcgat cgtgagtcgg ccgcggaaaa
    53101 atccactcac ggcctggtcc atcctccgca cgatatgacg cgctcgcggc cgatacccgg
    53161 gagggatata ccggcggagt tgtgcgaggg cgctgtcaaa ctgccaggcg aaaaaaaaga
    53221 aatagatcgg tatcagcacc agtgccaggg tgacgtccgc cgtggttccg atgacgctgc
    53281 caagcactcc gaaggcctgc cccgtcccgg aaaaaatcgg tttcaggatg gaaagagggt
    53341 cgtcccgaag actcgtggca atcgacgaga gtggttcgga aaaattcccc agggtgacat
    53401 ggtactgcgt ggcgatactc tggagatacc cgggtacccg ttcggcaaac gattgtacct
    53461 gctcggccaa tagcggtccc agccatgtca ccagccctcc cagcatcatc gctgaaagga
    53521 ggaggacgat ggacacggtc acgggccgtg ggatatgcca agcggtctca gcgcgccgga
    53581 ccagaggatt caccaagtag gcgagcagca acgcaaccag cacgggggta aacacgccgc
    53641 gcaggtaata gccgaaccag agcaggaaca ggatgccacc caaccagagg agatcccgga
    53701 ccggcgtaat ttcccacaaa tggcgattcg ccacagaagt gccccgttcc ttagacgtct
    53761 gcactcgcgg tctctcctcc gcaagcgtct cgacatagcc tggtttcatg aggcgttcga
    53821 tcctttctct cattcgtcga aacggtaggg gctaagctgt gtgacttgat tgttcggaga
    53881 acgaccgcag cgccaacgct gcacgctcaa tctgggcgtt gatttcgcct ccgagcaaga
    53941 tcaccacacc cgtcaaatag agccacagca tgagcacgat gacccccgca atggacccat
    54001 acgcagcgtt gtagttgccg aaatgatcca cataggcttt aaagcctaat gacagcccca
    54061 tccagagcag tacggcgacg acagaccccg gcgtcaccca gcgccagtca tgatcgacgt
    54121 cgggacagac ggcataaatg atggcgaggg cgagcagcat caacccgatc gccacaggcc
    54181 actgcagcac attccaggtc aagagaaaca gccatcccaa tcctatgagg tcggcaatcc
    54241 attcgccgat ccgctcgccg tagaggacaa gggtgatgga gatgatgata aatgctgcga
    54301 gaccgatcgt gagtagtgcc gccaccagcc gaactttcca gtaaggccgg gtttcctgcg
    54361 cgccatacac cacattgagc gattccatga tggccgtgac tccgctcgag gacgcccaga
    54421 gcgctcccag gagtccaagc gaaaggatgt cactcccgga gcctttcacg acactatcca
    54481 ggtacttttg cagcaatgat aaggcgtccg caggtaacac ggtccggaga taggtcatca
    54541 actccggcag cacctgttcc aacgggaaca ggcccagcaa tgcagtcagg aacagcagcg
    54601 ccggaaaaag agccaggaga aagtaatacg ccaattgagc cgcacggccg aggatttcat
    54661 ccttctggct gtcggtccaa agccgttgcc caagctcttt ccatcccagt ccgccgagtt
    54721 tccagggatt ccatcgtggg gatgcactgg tcagcgaggc cgacaccctg actcctctac
    54781 ttcatcggaa ctgtgatgcc gatccggccg aagacctggc gttgccgcgt ccttcagtct
    54841 ctgaatacga agcctggtcg tacgacggtc gggactgctt cccttgggag gtcagcgtca
    54901 cgccgagaga ccgggcgatt tcgggaatca gcttgtttgc gaattcgacc atgagcgtac
    54961 gcccggcttg cattaatgcg gccttggcct gctccgtatc gatctccaat tcacggctca
    55021 tggtttccca gatagtggag tgacttcgct gttccgttct gcgggccctg tgggtgggat
    55081 cgggatagta gtcgtaaatg ccttcggctc gacgagaagc ggttttgcct tccgtctccg
    55141 actccggcat gacctgtgat gcgtgagcgc ccggcggata ataggggtac accccgcgtt
    55201 gtgcacgcgt acgggcttcc aacagaccga tcgcgtatcc ggcgcaaatc gctccgccca
    55261 gcatcagcca tgggtagtca tcgaccttat ggatggggtc caaggcggct ttggttttgt
    55321 ccaccatctg cgtgacgctc tgggatcctt cgtcgagtaa gcgcgaaaat ttcatcgtgg
    55381 ctccctccgc cgtgtctttg atccgttgtt ccaacagctc gagcttttcg gcgatatcca
    55441 ttctcgtctc cacaatatct tttatgtctt ggtcgatagc agctgttctt tgatccattt
    55501 ggcatcttcc tttaatgagt aaaaggtgcg aaacggccag agccgaagag tggtgccgat
    55561 ggcgatcaga cgagcaaaga aggccgcgcc tgcggcagcc gcaacgagtg ccacgattcc
    55621 ataacaggcc cacagtggga ggccgctgta aaagtgcaac aggtggatca acgtcatcag
    55681 gagaaataat acagccagga aggccagcat catggcgatg ccggcgtgca tggcgctttt
    55741 gacgaccttc cccaactcgt gctgcatttc atgccgggcc agttggacct cctgggcaaa
    55801 caatcgccga agatcctcca ctaaccctgt gaccagcgag gcgatcgaaa tcggatgggg
    55861 attttccata tagccgtcct cttccggtta atcggttcga gcgcgggaga gcagatatcc
    55921 gcatcccagg ccgagcagca gtgtttggag cgggtaacgt cgaatgagaa tttcaaggtc
    55981 ctcgacgacc ccgccgatgc cctgttcctg taagtagaca gaggtttctt tgaccttgcg
    56041 cacgactgtg tccgccgcct cgcctgcagc gctgtctttg ggaagacggt cacggaggtg
    56101 gtccgcagcc gattccactg cgtcaccggc gcgtttcgcc atgtgttctg ccgaagtggc
    56161 ggtgtcgtgg atggcatctt gtattgacga gccggcctgt ttcgcccggt ctgccatatg
    56221 cttcatatcc tgttccatcg gccctcctcc tcactcgtgt atagggtgca tgttgagcag
    56281 atacttgccc agaatagcgg cgtgaccatg atgtttgaac tgggcagagc cctagtcagc
    56341 caggagtctc gcgccagcga tcgcaccgac attaaagagt cggcgactcc gtatgcacac
    56401 cctgaggttt tgacacaggc gggcggtgca tccgaagcgt gagatcggga cgaaggcgtt
    56461 tggcaggcag ccgtagggtg atcgattgtc cgcgctgggc ggaccggtgg agcgcttcaa
    56521 taatctggac gtcgaggaga ccttccgttc cattcggttc cggctgtcga tcatgtgtga
    56581 cacagcgcgc aaaatagatc agttgtggcg cgaattgatc gcccggtgta aacgtacgta
    56641 cgctcgtgcg ccctccgatc gtgacggagg ctttcaatcc accgacgtac tcatacgccg
    56701 gctcgacgcg tacttttccc ttggtgccga ccacctcata ggtcgcggcg tcggcggcgc
    56761 cgaaactaca ggtgaaggtc gcgaggcgat ctcgagaaaa tcgcatgatc gctccggccg
    56821 attcttcgac ggattgaaac cggtgatccg gtcctcgacc ggcgagggcg gtgacttctg
    56881 tgggctcatc ccgaaataga taccgggccg cgttgataca gtagactcca atgtcataca
    56941 ggggaccgcc gccgagctgt tgccgcaagc ggatatcgcc tgcccggacc tgttgtgtga
    57001 acaccgaatg aaaaaggcgc gggtcgccca accgtcccga ctgtacgagg tcgattgtga
    57061 agaggttgca ggcttcaaaa tgcaggcggt aggcaatcat gagtttaacg cgatgccgtt
    57121 ccgcagcctg tatcatgcgg cggcattcag ccgccgtgac ggccatcggt ttttcgcaaa
    57181 ggatatggat gccggctttc gcggctcgta cggcatattc gcaatgcagg ctgttgggga
    57241 gagcgatata gatcgcgtcg atctcgccgc tacgcaggca tgcgtcgaag tctttgtacg
    57301 ggtaggtatg ggtcacgccg tagcgtttgg cgaggacacg acgcttaacc ggatcgtccg
    57361 agacgagtgc ggtaagggtg gcggcagatc ccgtatgaga aaaagccggt aggaccgcca
    57421 tctgggaaat gtggccgagt cctacgactg ccacacgcaa cggtgaatga ctcacctcct
    57481 actactcctt tgtgaacatg aaaaaatgtg ccggcggaga gtcggcccca aacgcttcgc
    57541 atggcaaggc cgggtcaccc acgcggtgcg gtcgtcatgg catcgagcag aggaatgaga
    57601 tcacgctctt cgccatgaaa atggacacgc acagtctgca tcatatcttc aaagaactga
    57661 tccatggatt catcatcgtc cgtctccgcg tggcgcaatt catggatcat ggctttgact
    57721 tcctcatggt caagcagaac gcgccggatc actggagtgg cgtgttcctg gaggcggctg
    57781 tcttcctcga acaatctttc ttcccagtcg aagtgatcat ccagccgctg aagaatatcg
    57841 tcgacaatgg actgtcggga atccgactcc gtaccgagat atacctggaa tagggccagt
    57901 atatggcggt ggtcattctt cataattttg atgatgtcgg cggtctcgtg cagcgtcggt
    57961 ctctgttcca tagatccgcc tccgcgtggc atatcgtgag cgccggccgt taccggacgt
    58021 cctgtcgaag cagagcgcgg ggactctgtt cttcaagcgt gacctgtccg gtcgcgttgg
    58081 ccgtgccttc cagcatgatg gtggccgtga tgccctgagc agaggatcgg acatgatccg
    58141 gctgctggcg cgtaatgaga atgtccattg tggtgccgcc cgatcgatgg gtaccggtca
    58201 ccgtctgctt caagcgatcc acttgaggag agatgtcgac ggtcatcgct tgccgcaact
    58261 tgccgttcaa ttcacggtcg accagctgcc agtagccgat gcggatggaa tcgatcgcgg
    58321 ctttggactc attggccatt tggagatccg gaacagaaat actgcgtccc ccttcttcga
    58381 gacgaggagt cccccagtaa tagatcgtgc ctttgagatc gccactcatg tcgatcgcca
    58441 ccagcgcgcg gccgttggca tccgaggccg agacccgttc gatgacggcg gtatcggaag
    58501 cggtatccaa aaacaccgat tggtgaaaga gtttactctg caactgatgc gagatttgct
    58561 gataagacag cggtatccgc gctacgagcg tataaggctt tccttcgggt ggaatggatc
    58621 ctgaattgac cagggccact gtcggtgtgg cttccgtaca ggtcgcttca taggtaatga
    58681 acggcatctc tttcgctgtt cccgaaatga ctgtctcctg cgtggtccct ttctggccgc
    58741 cgagaatcat ttcccgagga ttgccataca tacaagcccg ggtgttgaga gacgcaatgg
    58801 ggatcgataa tgggccgccc aaatcatccc agattcgttg cagtggaatc ccgaactcct
    58861 tgggatgtac cgcttcagcc aaggccgttt taatctccga catgccgaac agatcgggaa
    58921 gctgttcgga aatcgggaca ttgaacatat tgcagcgcgc atcgctatca ggtttggtgg
    58981 tgacggctgt ctgtgccggt tcgaagccga aagatagagc atcgccgttc tgaatcatcg
    59041 tcaaccggcc tgtggcgtcg attgaggtgt ataacgggtc gagcctgcag gcacgtgaac
    59101 tgccacgcga ttcgatatca cctttatatt cggcatggat cgcgaccagc ccatcttgaa
    59161 tgtgaacatc aggctcacca accctcacaa aagtccacct gaactcctgc cccagggggt
    59221 ggccggtctc cgtgatcctt tcgggaatgg ccttgcggat cgcggtctgg atgggggtca
    59281 ggtctgtttt gatttgaacg ggcacctggg acacaggcgc ccgggaatcc tctttggtct
    59341 gcgctgggaa tgtgggcacg gcactggtca gaggaggcgg gaccggcttg gatggcgatt
    59401 tgggtatgga atggctgcag gctcccacca acagggcaga aaagagcaca ggcagtatat
    59461 gtgagacatg gcgcgtcata atcagcctcc tagacctcat cacagcagcg atcgtgcgat
    59521 cgccgcctcc cccagaagat gctcatcctg gtttcttacg gcgcttgaat ttgtaagttg
    59581 ttgttcacgg tgcgcacacc ggccaccccg cgagccagtt caacgacccg cattttttgt
    59641 tcggcggatt tgaccacccc gttcagggtc acgacgccgc gctccgtgtc gacatcgatt
    59701 cgcgaaaagt tcgacagccg gtcttgtgac agtttggcct gaaccgctgt ggtgatggag
    59761 gcatcgtcga tggtctgacc ggcagtcttg ccggtggtgg actggcaggc caccagggtc
    59821 atcatggcaa aggcgaacat gaggtgcgtg agtagtttca tcatgatagc gcatcctttt
    59881 caacgtagtg tgacagcatc actgactctc tagcgcggct cttctcagcc tcgccgtgat
    59941 gtcgcttctt ccgccgtgtt ctgggcagtc tgcatcgtct catccacgaa ctcacgagcg
    60001 gctcgccctg cctttcgtaa cgtttgtttg ccaccctcga cgtattcctg ccctcgttcc
    60061 atggcggagt cccaggctgc gcgtccctgt tcagtggctt catccagttc gtccttcgcc
    60121 ctggaggcat agtcacgcag agtcgagcga agttcattgc ctgactgagg agcaaggagc
    60181 aacgcgactc ccgcgccgat caatgcgccc gccatgaatg ccgaccagtt ggaagaatca
    60241 tccgtatgca tgtgcgacct ccttcaacgg taccgatgaa tggtgatgtg tagtgttccc
    60301 gcgacgtccg aacagatatc tttcgcgtga tttcagacta gcaggatgtg gcgatcctca
    60361 aactaggcat ggccctagtt aaggctacgg agctgctctg gcggtcagaa cgatgtggca
    60421 gcgtcgagac tcagaagagc ataaaggact cacatccatt gatcgttgcc ccggtagccg
    60481 ctcgcgagtc atagtgagat gcggtggttc cgtctgaatg ctcatgcgtg tcattgctgc
    60541 catcacaagc tcgcaggtcc aggcgtgggt acgtattatc ctcctcatgg cgtttgtgtg
    60601 catgatgacc atagggtgcg tctacactgc tccttttacg gacgccgaat gccggactgt
    60661 tcctcacagt attgcgacga tggaacgaat agccctgggc ggcctgcctc agagcatatg
    60721 gtttcgcggt gtctctgatt cc
//
LOCUS       DAOQPD010000014        60645 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_176_length_60645_cov_22.383628, whole genome shotgun sequence.
ACCESSION   DAOQPD010000014 DAOQPD010000000
VERSION     DAOQPD010000014.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 60645)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 60645)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60645
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_176_length_60645_cov_22.383628"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..524
                     /locus_tag="PK063_05230"
     CDS             <1..524
                     /locus_tag="PK063_05230"
                     /inference="COORDINATES: protein motif:HMM:NF019498.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HMZ96480.1"
                     /translation="ELKRIHMIGNRRLKGDVMTPWKRQGYALKSGEGPSIEFRGTKMT
                     VKLSGASSEESHSLIEMVHPSGVGPALHIHPTGAEAFYVLEGHYTIHCGEQQYEAAAG
                     DFVYVPKGLPHLYQSGVNGGKVLVLSPAGLERYFSEVAELLRVGPVTWDVEQAIAAQY
                     GQEFLDGLRHWGQ"
     gene            complement(561..1208)
                     /locus_tag="PK063_05235"
     CDS             complement(561..1208)
                     /locus_tag="PK063_05235"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96481.1"
                     /translation="MNADHPSSPSSPDMLVPEPSMNSTPADERSFHIRLAVFASVVII
                     AVVGAFVGYPTWQEYVSQQEAKLELRAYVNVRALGPPALKEGVSPRVRETIQNAGRTP
                     AYNDAIQAFITVADYPLIKNFERVTCPPDDSQPDKRKWFMGKVPRTETVRETPFTAEE
                     ITAIQTAKSALYYHGTVCYRDIFHESHRTDFCMFWKWDAGRLSPSLSCDQGNKTD"
     gene            1380..2741
                     /locus_tag="PK063_05240"
     CDS             1380..2741
                     /locus_tag="PK063_05240"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013739.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HMZ96482.1"
                     /translation="MGISPSLRGMSVIVAGAGLAGLTAAYELQRRGAQVTVVEARDRV
                     GGRVWTRRDGFAEGQHAEGGGDMIDPDQESIRRLAKDLGLTLSPILRGGFAFARQAAR
                     GPVITQASKAGDLWAQLAQAAEPWVRAHRLNERRWDGPIARQLAEQSVADWLDSIGAN
                     QQLRARLNGMRGFFLADPEHLSLLALVDQLSAESSALDHFYRIKGGNDRLATALADTL
                     NEPIQLKTIVCAVAQRRGQRRVTVRRGGQQDHITADAVVLALPATIVRRLAFSPPLPS
                     PQRKAFQDLQYGPATKTLLQFDRRFWRHQGAPLAYGTDLPIGAMWDGNEEQRGRSGIL
                     TLLAGGSASRDTQRLLAHGGAEAVAEQLKWLGATKAVLCASHHVSWEDDRFVRGGYAV
                     FQPGYDPEQRAWLSRPHGRILFAGEHTSLRWQGYMNGAVESGLRAALEVECLLGRLKS
                     NAH"
     gene            complement(2721..3365)
                     /locus_tag="PK063_05245"
     CDS             complement(2721..3365)
                     /locus_tag="PK063_05245"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96483.1"
                     /translation="MWQSRNQIQIPDNSNGTRFDLTDIQGNGPNVQRRVELTWNLSHQ
                     HSLRFVYAPLGFSGTGSFGSPVRFSGGTFAPGVPIDSDYKFDSYRLTYRYLVHESERW
                     RWRIGATAFIRDARVELRQQGRVASDSNVGFVPLLSTSLEYDIAPRWTALLDFDGLVS
                     TQGRAIDAALKVRYDLTDHWFMTAGYRVFEGGVDNDRYAFGWYNFALVSVGVRF"
     gene            complement(3520..4101)
                     /locus_tag="PK063_05250"
     CDS             complement(3520..4101)
                     /locus_tag="PK063_05250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HMZ96484.1"
                     /translation="MTAIVTIGTKRLRLRPFQTTDAEAVHRLAGSQDVAAGTFLPHPM
                     DRQAAQDWVTERLKDQAAGTGVTFAITLLENGELIGSIGMELMLVHEQGRLTYWLGRD
                     YWNQGYGTEAVTALVEYGFNSLSLHRIYAPHFHTNPASGRVLQKVGMTYEGRLREHYL
                     RFGQRIDVELYGMIRNEFLGLKVGEKGVADDHG"
     gene            4217..4423
                     /locus_tag="PK063_05255"
     CDS             4217..4423
                     /locus_tag="PK063_05255"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96485.1"
                     /translation="MDVAQVLIAIVGFGAAVTTYCLMRFPHMRREPFRQYRGCSVLVS
                     SLAALVVLCLALVVLIAQYAWHAR"
     assembly_gap    4577..4676
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            4987..8283
                     /locus_tag="PK063_05260"
     CDS             4987..8283
                     /locus_tag="PK063_05260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96486.1"
                     /translation="MDLVRATHSLHKPIRAKTRAFDHHVETQGPPAQKPPSIPAGLDR
                     TDWMCAALFSLAVAIACLLIARAMPSFLFQSMDFWFEADTLREISNMTRVHDDHYRTS
                     VHPLFSLLTFVPVYLIKHGLSVSPLRAVLLVGSLVGGLWGGTLYVLFRLLGCRKPDAI
                     VLTLLGLVSASALFWLPVPTSYSWGSLSIMLALVLLLYTERRPIGASVYVVASALTLS
                     FTVTNWMAGLLVSLARWPWKQAVQLSINALCLVVILWGVQKVIFPSAAFFIGQREEAS
                     FMNHPQAGGITNVASSIVFHSLVAPTVRFLKDDAYAQANADAFRLSERLTFQFSTPGS
                     GGPLGLVAVILWSGLLLNGLWRLVTLDHHLRFRLVLGSMLAFEVLLHMLYGEETFVYS
                     LNFMPLLLAVAACGALAPGRRIVTGVAAVLVVCVALNNWQQFQAATHTATQFTPQREL
                     MTAMMEKDPERPWPRSVGHVPLAVPGSPEGGTAYHEPGGDFSPQLPSFGVSLWLCDAT
                     GAPVVVSQTVPIHEITQEFAPSAHPTIPAITTKTPYYQATWTRLDASRWELRFKNETN
                     HVPVIVLRSVGPAGGPVTALNQEEGKVTVNHRWAVTATPAPDRIAMGDENTAGWMTEQ
                     SAVTSWSGEAGWGYARLQFSLGTTKPGEEIRVVLSDLRPPVEIEGYYKQAPKRARLAL
                     PDPRLQASMNAQITHLMMSLVDDETRPGDPAVFYRAWHRQGAYITAALARAGEPRVSR
                     VLSQFLAMHDFAGGSGPEADAPGLTIWALTESADYIGDKVHDEWLWPHILRKARRIEE
                     MLTAKTPLVEPYTIPAPHDFKHLRQTRTAVLAQPAREGLIVGRVGEEWPSLYVNAVSY
                     RGLVAAAEFAERLGKRQQAARWRTQAQGLLESWQRQSTHDSMQGSASPVSLRALADPS
                     SRRHQLKQLLTTYRPTADHTTSAGQLSQAHQALRQGKPEAVWTVLHRLWGEQASPGLY
                     TWEAALSSKDEVADGWQYARGWHNELAVTPDYETAALLLLLQQDMLAYLDEQAAEPTV
                     VIGAGITAGWLSQPMAVSNLALPGGSITWQWDGHAMRVTVRGPERAVRLGTAFPPGTS
                     LIVTHKPAIH"
     gene            8443..9465
                     /locus_tag="PK063_05265"
     CDS             8443..9465
                     /locus_tag="PK063_05265"
                     /inference="COORDINATES: protein motif:HMM:NF024880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HMZ96487.1"
                     /translation="MLKPEPAGGPTPQLFFQTANAYQRSQALKAAVELDLFTAIGLGH
                     DQVPALAQRCGAAERGVRILADYLTIQGFLTKEGDRYKLTPDSAVFLDRRSPAYMGSV
                     LGFLHAPKFIAAFEHLTEAVRKGGTVAGEAGTVAPEHPLWVDFARSMIPMMAKPAEEI
                     GIFVRQSQPNVKKVLDIAAGHGLFGVEIASRCPQAEIVALDWPNVLTVARELAQQAGI
                     ASRYRTIAGDAFQQEFGECYDLVLLTNFLHHFPVQTCESLLRKIHRSLAPGGRVITLE
                     FVPDENRVTPPPVAEFSLIMLATTPEGDAYTFREYEQMFAAAGFSRTELHPVAGSIEQ
                     VLVSTL"
     gene            9765..10757
                     /locus_tag="PK063_05270"
     CDS             9765..10757
                     /locus_tag="PK063_05270"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:TIGR04122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ligase-associated DNA damage response
                     exonuclease"
                     /protein_id="HMZ96488.1"
                     /translation="MSDLIRLQPEGLVGPGNRFHIDAWGQAAVNLITHAHGDHARTGS
                     AEYWCAEPCAPILRHRLGPDLRIRAVPYRKPVRLDDCWISFHPAGHILGSAQIRVEQG
                     SRVWVVTGDYKRDADPTCELFEPVPCDTMITEATFGLPIYRWASTRSVTGRIVDWWQR
                     CREEGVTALLFCYALGKAQRILAELTHFTQEEVLLHGAVAALTQIYREQGVSMVPTRL
                     VSDAEGPTEGRLILAPPSAHRSPWMKRFRAVSTAFASGWMAVRGIRRRRGYHRGFVLS
                     DHADWKSLLDTVEESRATRVLVTHGTSDTLARYLRDVKGAKAEALTTHFGEGED"
     gene            10757..12484
                     /locus_tag="PK063_05275"
     CDS             10757..12484
                     /locus_tag="PK063_05275"
                     /EC_number="6.5.1.1"
                     /inference="COORDINATES: protein motif:HMM:NF006701.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003910 - DNA ligase (ATP) activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA ligase"
                     /protein_id="HMZ96489.1"
                     /translation="MQAFAILFEQLDQTTATNEKVRIMTEFFRHQDPDTSAWVLFFLS
                     GQRPKQIVGSTKLRRWAQEKVGYPDWLMEESYAAVGDTAELIALVLAAGEGAVKHAPL
                     SRLSLGEWMVQRILPLAGMDDQARRSNILAWWEELETNETFILNKLLTGSLRVGVSET
                     LVYRAVAAAFSLSPAVIASRLVGTWQPSAEFFLRLSAPAEETQTGQRSDETLLPLPFC
                     LAAPMEGDPEELGDISNWQCEWKWDGIRCQVVKSGSRLEIWSRGEERITGSFPDLSRL
                     LSPVSGDWVIDGEIVAGDWHRPDAFQSLQRRLNRKKPSLALIASSPVSFLAYDLLQAD
                     GRSWRHHPLAERQAMLERTLHPYIGERLGISPLLALSSWEQARLLRETSRVEGAEGLM
                     LKAKDSEYVTGRKRGVWFKWKIDPLAIDAVLTAAQPGTGRRASLYTDYTFAVWAGDSL
                     ITVAKAYSGLTDEEIRELDGWIRKHTRERFGPVRMVEARRVFEIGFEGISQSDRHKSG
                     FALRFPRILRERTDKRVEDADHVATLETLLASFGSSAGRLGRARARAESLPGQEQLQF
                     ELGAGDVGS"
     gene            12481..15042
                     /locus_tag="PK063_05280"
     CDS             12481..15042
                     /locus_tag="PK063_05280"
                     /inference="COORDINATES: protein motif:HMM:TIGR04121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ligase-associated DNA damage response DEXH box
                     helicase"
                     /protein_id="HMZ96490.1"
                     /translation="MSSSAKVLRGIQRLNRMGPLRPRPDAEEQARARRKAWPTLSREE
                     AWKQWNEWFDRQGWSPFPFQVEAWQAFDAGRSGLVAVPTGSGKTYAAVGGPLLSLIAH
                     PIAGHQPPLTILYITPLKALARDIAQAIQQPLDDLGWPIDVDLRTGDTTATARRKFKE
                     RLPHVLVTTPESLAILLTDQGWKDRMRAVQAIILDEWHELLGTKRGSLLELTLARLRA
                     MAAGARVWALSATIANLEEAASIAVGSGLEPTIIRADIPRHIRIHCLLPESIQRYPWF
                     GYSGLSLLPEVVRQINPDQSTLLFTNTRSHAERWYQAILEARPEWSTVMALHHGSLDQ
                     DERQRVEDGIKSGALRLVVATSSLDLGVDFPPVENVIQIGSAKSIARAVQRAGRAFHR
                     PGEDTLVQLCPTNVMEILEASALRQGMQGGVLEERTPLEKPLDVLVQCLLNASFNEGF
                     DPADLCRQVRSAVSFRTVTDDEWSWALAFIRSGGALSSYPEFRKVEVVEGRYRFVSTE
                     AARRHKMNIGTILSDSGVTVQVRGGARLGMIDETFVAKLRPGDVIQFGGRTVQFLQMR
                     DMTAYVKPARQRSPVAAVWSGTILPLSVQLSFYLRREVDRLRQAVEGLNPRSPEIDAL
                     LPIARLQSSRSRIPSTAQTLIETCRTAEGHHVFVYTWEGWSVNEGLGHLVAYRLSRLR
                     PNTIAVSATNYGFELLSTEPLGSDREIGQALTTLDGLEEDIHASQNFPELARRAFREI
                     ARVAGLIYQGTPSARKTARHLQMSASLLFDVFRQYEPSHPLLAQAFREVHDRQLQIDR
                     LRGLMRRMGEQELLIVPIPRLTPFAFPLYVERIKSRLSTEKLEQRVARLQREVFR"
     gene            15043..15690
                     /gene="pdeM"
                     /locus_tag="PK063_05285"
     CDS             15043..15690
                     /gene="pdeM"
                     /locus_tag="PK063_05285"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:TIGR04123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ligase-associated DNA damage response
                     endonuclease PdeM"
                     /protein_id="HMZ96491.1"
                     /translation="MRIRIRDECVALLPERAMFWPTHSLLVVADCHLGKAETFQQQGL
                     WLPSQSGQQDLTRLSALVLSVDAQHVLFLGDLVHSLSGVTDAVVAEFARWLHEFSGSV
                     RVVLGNHDGGLARRWPKEWVKAERCDQVTIAPFRFKHQPIEGTVEADTFYWVGHVHPM
                     IQLAQGPDRVRLPAFVINDRQGVLPAFSSVSGGYDVPLRPDERRFAIGGDRIYEL"
     gene            15864..16310
                     /locus_tag="PK063_05290"
     CDS             15864..16310
                     /locus_tag="PK063_05290"
                     /inference="COORDINATES: protein motif:HMM:NF017088.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042314 - bacteriochlorophyll binding
                     [Evidence IEA];
                     GO_process: GO:0019684 - photosynthesis, light reaction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRC-barrel domain-containing protein"
                     /protein_id="HMZ96492.1"
                     /translation="MRYVIAIVVMCLSVATTVQYADARDRNGVFKASELIGMKVQGTD
                     GKNLGDIKDLVINPDDGAIDYAVLDFGGFLGIKDKYFAIPWDALQVASGKDKILIDAT
                     KRDLKNAPGFDKNHWPDFGDLAQTTVIYEFYGVPAPNTSGQHKATR"
     gene            complement(16342..18114)
                     /locus_tag="PK063_05295"
     CDS             complement(16342..18114)
                     /locus_tag="PK063_05295"
                     /inference="COORDINATES: protein motif:HMM:NF021489.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HMZ96493.1"
                     /translation="MDRAGDPIVKPRRRPHFVHVLSSLIFLCLIESVSLLPADARSFV
                     LSRFDVELQVLSGGELLVTETVSPRFEGAWNGIERLIPVEYRTPQGFNYTLFLDRISV
                     TDEQGTPLKFESSRERHYRNLRIWIPGAADATRTFVLKYLVRNGLKFFEDHDELYWNV
                     TGDEWDVPIEQASVRILLPPQATGVRAQAFTGAYGAREQAATVTILGSGIEMRMTRPL
                     GFREGLTAVVGWDKGLVAAPTVVEQTRMTLVSNWPLGIPLLAFLVMYRLWSTRGKDPR
                     LRPIAVMYEPPDQLTPAEAGTLVDESPDTRDITATVVDLAVRGYVRISERKAEHLFGL
                     WSSMDYAFQRTKPRQEWAALPSFERLLLEALFKDSEVDEILLSSLENRFYKSLPGIHD
                     AIFQSLQKRTYYSQRPDRVKQGYLIGGIAFGMLLTIGLGILADRWGLAPLTVFVAGLL
                     SGMIVIGFGRIMPARTQQGTRALEGVLGFEEFLTRVEADRFDRVIKTPELFEKFLPYA
                     MALGVEKNWAAAFETIVMTAPAWYQGSDLTQFNTRGFTSRMGDLASRTGSTMTSAPRS
                     SGGSGFSSGGSSGGGFGGGGGRGF"
     gene            complement(18116..18664)
                     /locus_tag="PK063_05300"
     CDS             complement(18116..18664)
                     /locus_tag="PK063_05300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HMZ96494.1"
                     /translation="MGWIILAVLVALVLVVIGMYNSLVRLRAAAESAWADIDVQLKRR
                     YDLIPNLVETVKAYAAHEKGALEAVITARAKAMSAQGPEAKAVAENQLSQSLKSLFAL
                     AEAYPQLRAVEAFNQLQGSLNQVEDALQNARRYYNAVVRDYNAKRQEVPTNFIAGWFN
                     FAGRQFFELTETTQREPPRVQF"
     gene            18930..19256
                     /locus_tag="PK063_05305"
     CDS             18930..19256
                     /locus_tag="PK063_05305"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96495.1"
                     /translation="MVHRNGRIGLGLVVLLWCVLAGGTLAVPLTRAEEPTIEFNSPDV
                     LRQILEQQVGKRVKVRLLSGQDVDGKVAKVGTQAVALTELSGMEFFDATIRLDQVAAV
                     IVRRGK"
     gene            19308..19817
                     /locus_tag="PK063_05310"
     CDS             19308..19817
                     /locus_tag="PK063_05310"
                     /inference="COORDINATES: protein motif:HMM:NF025196.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4188 domain-containing protein"
                     /protein_id="HMZ96496.1"
                     /translation="MPVPILRRTVDLSGFPDLVVIYLGMRVNRWTGLKTLFGFGPQIA
                     ASVDAQPEGLLLHESLLWSLMPPHVGMRQYWRDFDALERWARSDPHRQWWQQFLRDTG
                     GTGFWHEAYFMRGGMEAVYNDILQDIGFLRFAPIRPAKGAQFTARSRAGRTGESALPP
                     AVLEEDLDR"
     gene            complement(19851..21236)
                     /locus_tag="PK063_05315"
     CDS             complement(19851..21236)
                     /locus_tag="PK063_05315"
                     /inference="COORDINATES: protein motif:HMM:NF024883.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HMZ96497.1"
                     /translation="MGTAALALKDLWPCFEGIIPATIATCAKDGTPNISYVSQVHYVD
                     PEHVAISFQFFNKTRKNIAEHPFASVMVLDPRAMQAYRLSLTYERSESSGPLFQAMSL
                     QLQAIASHAGMSDVFRLRAADIYAVRHIERVDGFTSWPVPAHDERPPSLFIDPNLHAL
                     RVVAEQLNRAECLGELLETALRCLDEFFGLHHTMLLLVDEKRRTLQTIASRGYDENGV
                     GSEVGFGEGLIGMVAAAKLPLRLSGLDYTLRYARAVRDRAQALSGPESLCREIPLPGL
                     SNASTQIAVPLIIRHRCLGVLVAESLEPLTLLIREEAVMAIVAGHLAAGIEQSAQEAD
                     DSVAVEAPAAAAPPLHSPLSHRSFCFYQADDCIFVDGEYLIKNVPGRILWRILKQHQD
                     EHRVEFTNRELRMDSWLGLPEWKDNFETRLILLRKRLEQKCPDVRLVPRGRGRFALET
                     SVKIILSEKPA"
     gene            complement(21240..21695)
                     /locus_tag="PK063_05320"
     CDS             complement(21240..21695)
                     /locus_tag="PK063_05320"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96498.1"
                     /translation="MIPPAIVDLLQTGVSVNVGTRDKNFMPECTRGWGIWVAANRTTV
                     TLLLTEPASARTLANLRDNGLMAITCSRPTDHVTCQLKGSVTQIRQATPQDYERQQQW
                     RHAFLGELIAVGVPAEQTDALIMQPAVAIEMQVTGVFAQTPGPGAGEQV"
     gene            21837..22664
                     /locus_tag="PK063_05325"
     CDS             21837..22664
                     /locus_tag="PK063_05325"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96499.1"
                     /translation="MKSHILLSLCLAVLAATPLTGQAQAAQPGNVTITATDYGFKSPE
                     QVPSGLTAIEVINEGAEVHHAQLVRLAPGKTPADFAAAMKADPEHPPIWATFVGGPNA
                     VVPGDRATAVMDLQPGQHLALCLVPNKAGVAHVAMGMARPFMVTETIGTRIAEPKPDV
                     VITARDFQFVLSKPITAGSHTIQLLNEGSQTHEVVLVKLAPAATAKDFIAAFEPGAVG
                     PPPGRPLGGIVGIEQGSRGLFTAMFDPGPYALICFFPDKKTGAPHFAQGMTWEFDVR"
     gene            22719..25340
                     /locus_tag="PK063_05330"
     CDS             22719..25340
                     /locus_tag="PK063_05330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HMZ96500.1"
                     /translation="MAPYTMPMHDMMPSTVEPMMADRGAALLQVAEVIAAHHDLPSLF
                     QDLAQCLPVVAPFDFVGLVLHDAAKHVMQVHVLETAEAKRVTRRLDGLEIPMKDSASG
                     WVWEHQQPILIPSLAAESRFQVGMDALRGIGVQSVCFFPLTTAMRRLGAIGFGCLKPF
                     AFDEGTVSFLNQVAKLVAVAVDNVLHHQDLARDRDRLRLLLEVTESIASHHDQSLLLA
                     DLAKRLPQVVPFDFMNVVRHDPSRDVMRLWLLVTSEQSTIEPGLETPVDESPGGLVWK
                     TQEPLTVDDVEREPRFPALMTLFRANGVRSFCVVPLTTAHRRLGAMGFGSLRPRVYLD
                     SEIAFMKQVAQQVAVALDNALNSESTLAYQSQLTRERDRQRLLLEVNNAVVSHLDLDQ
                     LFPAVSACLRRVIQHDGSSLLLCDEETGRWRIHVLDFDRNENFIEEGRIEETTQSPSC
                     LAITTGKAALFNERDLLAMGGASPCAQDLLDRGIKSFCSVPLLSRNRSIGALNVGRRR
                     DAGFDPEDVQLLGQVAQQIAIAVENALAFREIAALKDKLTKEKVYLEEEIQTDYNFEE
                     IVGESRALKRVLNQVQTVAATDSTVLILGETGSGKELIARALHNLSARRERTFVKLNC
                     AAIPTGLLESELFGHEKGAFTGAIATKIGRFELADRGTIFLDEVGEIPLELQVKLLRV
                     LQEQEFERLGSTRTMRVNVRVIAATNRDLSHMVDAQQFRSDLYYRLKVFPVTVPPLRE
                     RVEDIPVLVRHFVQKFASRMKKHIETVPTDAMRALQAYGWPGNVRELENFVERAVILS
                     SGSELFVPTAELKRPVSPSNGSATTLEDAERDHIIKALRDTHWVIGGSSGAAARLGMK
                     RTTLQSKMQKLGIVRPQ"
     gene            25578..26531
                     /locus_tag="PK063_05335"
     CDS             25578..26531
                     /locus_tag="PK063_05335"
                     /inference="COORDINATES: protein motif:HMM:NF020893.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HMZ96501.1"
                     /translation="MESVTELLEQHGAWVLFGGVLAEQLGLPFPALPLLVAAGVLVGT
                     GHLSWSGALIAALSATLLADIVWFLAGRWRGRPVLTLLCRIALEPDACVRRTEDFFRK
                     HGVQSLLVAKFIPGLSTIAPPLAGIVGLGLPVFLLYDALGAAVWAGSGLGFGLLFTEE
                     VALALTYSEQVVPALLLAAVVLLPAYIGWKAWHVRRQLQAVPRMTVADLLDKLAAPDP
                     PLLIDVRTRLAVEAEPGLPNALQMSLEDLARRHGELPRSRDLVLYCACPADAASAQGV
                     MLLQRKGFTRVWPLAGGLHAWRAIVDGPEPVPMIQVERLAV"
     gene            26567..27094
                     /locus_tag="PK063_05340"
     CDS             26567..27094
                     /locus_tag="PK063_05340"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96502.1"
                     /translation="MEFTMPTTEQAHWGLRAMKTVALADGVVDESERHMLEAVQRVFG
                     THHDVDGLQPLAPEELAAGLPDQQIRRQLVNGLIVMSLIDQDVKRAEAELVERFASAL
                     QVTLPEVTNLRHVVKKELFHLRLDLVRRSMIAPLFRQMPTGRQSEFGTRQHPALPRKK
                     WRELWQKNRWFTAMV"
     gene            27200..28327
                     /locus_tag="PK063_05345"
     CDS             27200..28327
                     /locus_tag="PK063_05345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HMZ96503.1"
                     /translation="MNRRGWIGSSLLMLTVIGIGVGLAVWKYGSIQDQAAASTNQPEP
                     MEVVTLAVARAVDHHQTATSIGTVLALRSITLRNELAGTVSQVRFTPGQIVEAGTVLV
                     ALDVSVEEADLRAQQAQAVLARTVLDRRRALTQDLAAAQEEVDRAGADLDVVQAQIAR
                     TKALIARKTIRAPFRARVGLADVHPGQYLNEGTQLTTLQGIDEAVHVDFAVPQHVAAG
                     LRHGDLVDVYPAGDTSVLQAKIVALDARIDPATRNAMVRARIDRSPSMPTPGAAVRIK
                     VRVGAPRSAVAIPVNAVRKGPGGDQVFVINSDGQGKSRAQVRHVESGAMSGDDIIVYA
                     GLAAGEQVAASGAFKLRDGVLVVAAGGPVAKSDATPSPEQP"
     gene            28345..31428
                     /locus_tag="PK063_05350"
     CDS             28345..31428
                     /locus_tag="PK063_05350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HMZ96504.1"
                     /translation="MRSFTDVFIKHPVLAVVINLVIVLVGWRALTTLPVQQYPKIESS
                     SVIITTVYYGASAETVRGFLTTPIERVVSAISGVDYLESTSRAGISTVTVHLKLNHSS
                     TAALAEVTARLQQVRSELPAEAEPPAVEVQRADRPYASFYLSFTSPERTVPALTDWLL
                     RSLQPQFATLTGVQRVTIEGGRQIAMRVWIDPDRLAAYNLSPGDVQAALRRNNYLAAV
                     GRTKGNLVQINLLANTDLRSTEEFEDLIVTDRGGAIVRLRDVARVENGAEEAEMVAKY
                     NRTEGVYLGIWPLVGSNEIEVAHRLREEMDRIRPTLPKDIDMQLVWDGTMFMRSALEE
                     ITKTLGETVLIVATVVFLFMGSVRTALVPLVAMPVSLVGAAIFMYAFGFSLNLLTILA
                     IVLSVGLVVDDAIVVVENVERHVREGKSRIQAALLGSRELVGPIIAMTITLAAVYAPI
                     GFQGGLTGSLFLEFAMTLAAAVVLSGVVAITLSPVMSSYFVHPEGKEGRLTKMVNRVF
                     DATRAGYGRLLDGALEMRWAIVVVALLVMVAAWPLYQFSRQELAPVEDQSHISLFLEA
                     APDSTVAATNRDSLKVIDALRAFPEARFTWSLTSSWGGFGGLVAKDWRERSRSTELMY
                     GQVYGAVSQIPGLRVFPRLDPPLPTPGQYDVELILESQLPAEQLMETTAAVLGAGWQS
                     GKFLYVDTDLKLDLPEARVLIDRERLADLGFDLARVGQELGTLLGGAYVNRFNFYDRS
                     YKVIPQIGDKDRATLDPLLDLKIKTPGGQLVPVSTFTRIETSTAPRTLNRFQQRNAVR
                     IFGGVKPGVTKDEALRVLETAAAAAAGSRATLDYAGESRQIRHEGSALIVTLGFAVVL
                     IYLVLAAQFQSFRDPLIVLLGSVPLAISGALVFSFLNLTTINIYSQVGLITLVGLIAK
                     NGILIVEFANTLQARGLSKTAALREAAMTRLRPVLMTSAATVFGHLPLVLVSGPGAAA
                     RNSIGMVLVTGMTVGTLFTLFVVPVFYSLIATRHQPAEELEPAEEPGLQLAGAKG"
     gene            31440..31745
                     /locus_tag="PK063_05355"
     CDS             31440..31745
                     /locus_tag="PK063_05355"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96505.1"
                     /translation="MLKITSEQTGDSARLTLEGSLSGPWVTELERTWQTVRLSGIFAP
                     VVELVGITFISEDGKALLARMWREGAALVAHGCCTRHIVGEITGAAPVAGPGQCDPA"
     gene            31758..33230
                     /locus_tag="PK063_05360"
     CDS             31758..33230
                     /locus_tag="PK063_05360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux transporter outer membrane subunit"
                     /protein_id="HMZ96506.1"
                     /translation="MRMIACVITLLLVTGCAVGPDYSRPDLQMPTGFRMAVSDQETQS
                     FANLPWWDLLQDEELRRLIRVALAENKDLQRAVASVEEFQSRLLISKMDFAPKADVTA
                     NAPSFGRKANFLFPGFPNPFNYYLQGNLSWELDIWGRVRRSNEAARGDLLAREEARRA
                     VVLQLVSGVAEAYFELLQFDMQLGVAQRTLKSWEESVRIAEARLRQGMISRIDADQFE
                     AERANAAARAAELTRQMVQKENQLSILLGRPPGQVARGRSLTEQVLPPEVPAGLPSEL
                     LQRRPDLVQAEQELAAATARIGVAKADRFPKLSITGILGVASPQLSRLIANETAFGVV
                     GPGLAGPLLNAQILGFQQDAAEAQSRKVLARYEQAVLVAFREVEDALVAVRTSREQRD
                     AQAQQVDALRSALRLANLRYKGGLANYLDVLVAQRNLFEAELALTGTHRLQLVSVVQL
                     YKALGGGWSPLDMAQQQPGQAPGTRGHALPAAGTSPAGHG"
     gene            33655..36879
                     /locus_tag="PK063_05365"
     CDS             33655..36879
                     /locus_tag="PK063_05365"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ96507.1"
                     /translation="MPMKPVILFVDANSVHVNALREALHGEEAELLCAASSAEAAEVL
                     LTREVVLVVMAARLLQTEGFKCAETLRGMKRTRHVPLILITEAGDDEQLTIPANDAGI
                     LDSLPTPIDPRQWRRKFRMYLEVSRQRQELSQQRMALRTALDEQRGMQAQLRDEEERY
                     RLALTATRDAVWVWNIETDSQVWNQAGADLFGWSEVVEQPQPAQWWVDRVHPDDRERV
                     GGAFHEAIGTPSVTHWADEYRFLKRDGTYAWVLDHGYIVRDVRGSAKRAVGAMQDITE
                     RKRAQEIAAHFAAVVGSSFDAIVSKTPEGVITSWNAAAERMFGYSASEMIDHTAHRLI
                     PVELHAEENDILARISCGESIQHYETVRLTKDGRRVDLSLTISPIRDSKGQIIGSSQI
                     ARDITEQKRQRTALKESEELFRALVDQMSQLAWMMDDTGNVYWFNQRWYDYTGMTIET
                     MHGEAWDQAHHPDHRARVLSSRRRSLETGEPWEETCLLRGKDGQYRWYLTRAVPIRDD
                     QGRIVRWFGTNTDITEHKRTEEDLRTAEQALRQSDTRFRELVERSPFGIYVVDAEFRI
                     AHMNEAGQKGAFCNVRPVIGRDFGEAMRILWPEAVAADIIKQFRHTLETGTPYRSRDF
                     INPRADLQQTEGYEWELHRLTLPDGRHGVICYYYDSTRLRMVEVALRESGERLQAAAA
                     DLEKRVDERTRDLVRSQADLRALASELNLTEQRERKRLAGELHDHLQQMLVFGKLQLG
                     RGMMQTGVDPECMEVIRGVYGMLSEALTYTHTLVAELCPPVLREHGLLAGLRWLADYM
                     KRYGMKVTVKLPDEEDLALPEDCTILLFQSVRELLMNAHKYAGTGLAEVALVHGQGAL
                     MIHVRDRGKGFDSAAATSADLAVGGSSSKFGLFSIKERMRTLGGSFAIASAPGQGTTA
                     TLRLPLTSRAAGAERVGDEKEVPAGTPAVQPNPMGTRPIRVLLVDDHVMIRQGLRAVL
                     EGYSDIELIGEAGNGEEAVALVDRLEPSVVVMDINMPKMNGIEASGRITMRHPAVAVI
                     GLSVNASADNQSAMLKAGARQLLTKEAAAEQLYGAIKSAVGISA"
     gene            complement(36918..37784)
                     /locus_tag="PK063_05370"
     CDS             complement(36918..37784)
                     /locus_tag="PK063_05370"
                     /inference="COORDINATES: protein motif:HMM:NF012363.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HMZ96508.1"
                     /translation="MKNLLFPIMMLSLSLAASGCSQATFTAVNLPTRFHEMTVVQDVA
                     YSPEPACTLDIYVPAGAGHQPLDVIVFFYGGRWTEGEKHNYRFVGAAFTEQNFIVVVP
                     DYRKYPRVRFPEFVEDGAKALAWVYDHIAGYHGNPERIHVAGHSSGAHIGALLTADAG
                     YLANEGKDRSRVIRDFAGLAGPYAFTPDEPDLEDMFGPPSNYPNMQVTTFIDGRQPPM
                     LLLYGDADRAVKVANLERLEQRIKEKGGRVETQIYPGAGHRDLAAALTWLNLRRTPVL
                     LDMQRFFRSSVR"
     gene            38081..38479
                     /locus_tag="PK063_05375"
     CDS             38081..38479
                     /locus_tag="PK063_05375"
                     /inference="COORDINATES: protein motif:HMM:TIGR00149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="secondary thiamine-phosphate synthase enzyme
                     YjbQ"
                     /protein_id="HMZ96509.1"
                     /translation="MTKLLRITTKQLKEIVDVTELLQATIRNANMKEGLCSVFVTHTT
                     AAVTTGEIGEGTEQDFLQIVEEVIPRIQFRHAHDPSHAWSHMAASMLGPSLTIPVSGG
                     TLVLGTWQSVMLVELDGPRDRNVHVSLMSF"
     gene            38541..39083
                     /locus_tag="PK063_05380"
     CDS             38541..39083
                     /locus_tag="PK063_05380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043169 - cation binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemerythrin domain-containing protein"
                     /protein_id="HMZ96510.1"
                     /translation="MAEIPAGGVIADFLAEDHRRLDALLQATDAHPGRIDREAYDQFR
                     AGLLRHIGMEEKLLLPALQRWRGGEPLPVAARLRLDHGALATLLMPTPTAQILATIRR
                     ILSEHNRIEEGPDGLYALCGQLPDTEATRLWDALRAAPTVSVMRHSDSPAVMKTLEGA
                     LARAGYRLEALAPREEGESR"
     gene            39106..40206
                     /locus_tag="PK063_05385"
     CDS             39106..40206
                     /locus_tag="PK063_05385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96511.1"
                     /translation="MMIRHPRRLPLLALGMLALLTGLWAGVARLGWDVPLPRSGFSSL
                     HGPLMVSGFLGTLISLERAVALGRSWAYAAPLLTGLGALVLIAGGPLVVAQLLLLSGS
                     AGLAAIFAAIIRRHPALYTFTMGGGAIVWAVGNLLWVLGWPVFLVVFWWAAFLVVTIA
                     GERLELARLQQVTRGAQTAFLLFLGVLGAGLLLLGWWFDGAVRLFGAGLAALALWLGL
                     NDIARRTVHQTGLTRFIAICLLSGYAWLGVSGLAAMVYGGVPVGPQYDAMLHAFFLGF
                     VFAMIFAHAPIIFPAVLGARMTYRPVFYAHVLLLQATLMVRLVGDAAGWGAGRQIGGL
                     LNAVTLVLFLANTVTALGSLPDRPVVTSRAGS"
     gene            40256..40579
                     /locus_tag="PK063_05390"
     CDS             40256..40579
                     /locus_tag="PK063_05390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HMZ96512.1"
                     /translation="MTREKQGAQSDPRVMEALRQVVDPELGINIVDLGLVYGSEVREG
                     QVHVTMTMTTPACPMEELLMEMVHSAILRELSEARSVEVDLVWDPPWKPDMMSPAAKA
                     QLGRT"
     gene            40639..41889
                     /locus_tag="PK063_05395"
     CDS             40639..41889
                     /locus_tag="PK063_05395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HMZ96513.1"
                     /translation="MTENQSQQVRALVDEVYRTQSRQVLATLIRLLGDFDAAEEALHE
                     AFAVAVEQWAREGVPANPRAWLVSTGRFKAIDGMRRRARFDASLPDLAHHLELTADPV
                     IDEGEDSVEDDRLRLIFTCCHPALSPEAQVSMTLREVCGLTTDEIARAFLTKPTTIAQ
                     RIVRAKGKIRDARIPYEVPSETDFPDRLDAVLRVVYLVFNEGYSASSGDSLTRHDLSG
                     EAIRLGRVLVGLLPEAEVLGLLAVMLLQDSRRAARTSPTGDLILLEQQDRSLWNRDQI
                     AEGMALVELALATRRVGPYTIQAAIAAVHAEAPEAALTDWAQIVGLYDVLLQAEASPV
                     VELNRAVAVAMRDGPSAGLALVDAILSRGDLTNYHLAHSARADLCRRLGRNTDAAASY
                     ERALALTQQEPERRFLEGRLRELG"
     gene            42028..42441
                     /locus_tag="PK063_05400"
     CDS             42028..42441
                     /locus_tag="PK063_05400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HMZ96514.1"
                     /translation="MAKRTPTRKTTKKADCPASLVWFDIPADDLARAKKFYSALFGWK
                     ISRFPAMPDYWHIDTGGEKATLDGGLLPRQAPRQPITAYVSVPSVEKAAAKVQKLGGT
                     VCKSKTPVPGMGYFVICQDTESNTFALWEMNPQAT"
     gene            42496..42852
                     /locus_tag="PK063_05405"
     CDS             42496..42852
                     /locus_tag="PK063_05405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciI family protein"
                     /protein_id="HMZ96515.1"
                     /translation="MKYLCLVYVEEKILHALPSAQRQTLSDESMSYCDRLQKLGQLVT
                     ASPLHPVETATTVRVRDGKTSTIDGPFAETKEQLGGFLLLDVPDLNDAIRIASQFPAA
                     RIGSVEVRPMKEQGCA"
     gene            42940..44121
                     /locus_tag="PK063_05410"
     CDS             42940..44121
                     /locus_tag="PK063_05410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HMZ96516.1"
                     /translation="MSRVRVLVGTRKGAFILTSDGTRKQWDVTGPHFGGWELYHLKGS
                     SADPNRLYASQTSSWFGQVIQRSDDGGKTWNPPGTKPEDLMGADGMPNGASNMFVYDQ
                     SAETGKPLTTHQHYDGTQRPWEFKRVWHLEPSLTDPDTVYAGVEDAALFRSTDGGRTW
                     QELAGLRDAKGKLWQPGAGGMCLHTIVQDPANPQRMHIAISAAGVFRTDDGGKSWRPT
                     NRGLKSQFELPDPDAEVGHCVHCITMHPSRPNVLFMQKHWDVMRSDDGGESWHEISGN
                     LPTDFGFPIAVHAHEPNTVYVVPIKSDSEHYPPEGKLRVYRSRSGGNEWEPLTKGLPQ
                     QNCYVNILRDAMSVDSLDPCGLYFGTTGGQVYASADGGDSWAPIVRDLPAVLSVEAQT
                     L"
     gene            44317..44613
                     /locus_tag="PK063_05415"
     CDS             44317..44613
                     /locus_tag="PK063_05415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoaD/ThiS family protein"
                     /protein_id="HMZ96517.1"
                     /translation="MVRVILPQHLRTLAKVEGEVSLEVVGAVTQETVLDALEVRYPVL
                     RGTIRDHVTKRRRPFIRFFACEQDVSHDSPDVPLPESVAKGAEPLLIVGAMAGG"
     gene            44649..45011
                     /locus_tag="PK063_05420"
     CDS             44649..45011
                     /locus_tag="PK063_05420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciI family protein"
                     /protein_id="HMZ96518.1"
                     /translation="MKYLLLVHHSEEAFAKMAETTRREMLAESVQLTHQLHAKGQYVS
                     ASPLHPTSTAARVQVREGRAIVTDGPFAETREQTAGYFLVEASGLQDAIDIAARIPGA
                     RLGTVEVRQVREIDGLPE"
     gene            45221..45688
                     /locus_tag="PK063_05425"
     CDS             45221..45688
                     /locus_tag="PK063_05425"
                     /inference="COORDINATES: protein motif:HMM:NF013098.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HMZ96519.1"
                     /translation="MSTSHAKPIPDGMHTITPHLICAGAADAIEFYKKAFHAVELGRV
                     PGADGKLLHALIRIGDSPVMLVDEFPDHHTLGPKSIKGSPVTIHLYVKDVDTVFNRAV
                     SAGAKSTMPVSDMFWGDRYRQLGDPFGHRWSVATHVRDVDPQALQEAARKACE"
     gene            45731..46102
                     /locus_tag="PK063_05430"
     CDS             45731..46102
                     /locus_tag="PK063_05430"
                     /inference="COORDINATES: protein motif:HMM:NF018893.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1428 domain-containing protein"
                     /protein_id="HMZ96520.1"
                     /translation="MRYVDGFVLAVPKKNVNAYFKMAKKACKVWTEHGALEYRECVGD
                     DLAVKMGLPFPRLAKLKQGETVVFSWIVYKSRSHRDRVNAKVMKDPRINEMCDEKAMP
                     FDVKRMAYGGFKVMVDGGTRS"
     gene            46296..46721
                     /locus_tag="PK063_05435"
     CDS             46296..46721
                     /locus_tag="PK063_05435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciI family protein"
                     /protein_id="HMZ96521.1"
                     /translation="MRFMIIIKATKDSEAGVMPSQQLLSEMGTFNEELVQAGVMLAGD
                     GLHPSTKGARVRFSGTRRTVIDGPFAETKELIAGYWLWQCGSKEEAIEWVKRCPNPMP
                     GESEIEIRQVFEAEDFGAEFTPELREQEDRLRAQMAQNQ"
     gene            46891..47490
                     /locus_tag="PK063_05440"
     CDS             46891..47490
                     /locus_tag="PK063_05440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1579 domain-containing protein"
                     /protein_id="HMZ96522.1"
                     /translation="MRVTSILLACLCTSLMTMPVSAKEKKSEKAMDPQAMMEVWKKAA
                     MPGEPHKLFASLAGSWTTQTKEWMEPGKPPSETTGTAEMKMLLDGRFLYQEFNGTMMG
                     QPFAGIGIDAYDNMTKKYVTAWMDSMGTGIFTMQGTSSPDGKTITLKGSHPEPGGGQM
                     HHRAVWKIIDQNSQTFEMYGTHGHGKEMKFMEITYTRKS"
     gene            47878..49074
                     /locus_tag="PK063_05445"
     CDS             47878..49074
                     /locus_tag="PK063_05445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HMZ96523.1"
                     /translation="MIRRWRWSTIAPMVCGWLALALVPGCKQEAGSAPAPTVPEVGIV
                     VATAQDVPDEPEFIGQAESSRPVEIRSQVTGILKQWYFKEGRDVKKGDRLYQIDPVPF
                     HAAMLSAKAKVAQSEARLVQANQNLTRVKPLLAEQAVSTKDVDDAVAEQLAAKAALEG
                     AKAELVKAKFDLDNTLIIAPIDGMIERTRVYEGRLVSAQTDLLTMIHQVDPMYVIVSA
                     PESFLLKRRRDTDAKRIQHPGVYQLRGVLTFVDGTTYGHEGVLDLLDVGLKTDTGSRQ
                     ARVVFPNPDRVLLPGQFVRVRFKGTLKTGAILVPQRAVQQGAKGSIVFVVGKDDKVEM
                     REILASSWQGSQWIVEEGLHVGDRIIVEGLHKIAPGAVVKPVPVPAAGAATAPSAAPA
                     PPEPAS"
     gene            49071..52253
                     /locus_tag="PK063_05450"
     CDS             49071..52253
                     /locus_tag="PK063_05450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0042908 - xenobiotic transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="HMZ96524.1"
                     /translation="MISHFFIDRPIFASVLSIVIMVLGLVALQALPIAQFPEITPPVV
                     QIEADYPGANAEILADSVARPIEVQLPGIDNLLYYDSTSTNDGHMSIKLTFEIGTDVD
                     IAQVQTQNRVKLAEPQLPPEVVRQGISINKVSPDLLAVVALSSTDPTHDTVYLSNYAI
                     LRVLDNLKRLRGVGNAVVFGSQNYSMRLILDPIRMAQLSLTPTDVANVVREQNRDFPA
                     GTIGREPALKGTELTIPVITQGRLTEVKDFEDMIVRAMPNGSMVRLKDVARVELGAQS
                     YTLEGRWNGKPNVFLLTFLSPGANALETVKRVRAELTEVSKAFPTGVSYDIPYDTTRF
                     IDVSIKEVVKTLAEAMVLVILVVYLFLQSWRATLIPGVAVPVSLIGTFAGMQALGFSI
                     NTLTLFGMVLAIGIVVDDAIVVVENCERHMTQGKLSAKNAAKRAMEEVTGPVIAIVLV
                     LCAVFVPVGFLGGITGELYKQFAITISIAVIISGFVALTLSPALCALVLKPGEERHHG
                     LFGLFNRTFSWMQGRYISTVGMALTRRLLSVAVFAVLLTGVVLLFKTIPNSFLPEEDQ
                     GYFITIVQLPDGASKQRTDTVLSKIENYFLANPAIHSTDALSGQNFVFSTRGPNAATM
                     FVPLKHWDERTAPQQHVKALIGAAYGEFAKIPEALILAFNAPSIRGLGATGGFSIQLQ
                     DPSGGDFNKFSAVAQEFVAKARQNPAIGAIGTSFRVSAPRIFAKVNRERAKALGVPIS
                     EVFDTLQAYFGNLYINDFVKFGRVFRVQTEAEAQYRSTPDDISKIYVRAVGAQGPTMI
                     PLDTVVSTEFSSGPDPVTHFNGYNTALVLGSAAPGVSSGQVLDALDKLGKEVLVPKGY
                     GIDWSGISYQERMVGNQSLYAFGFGLLMVFLVLAAQYESWVVPFAVILAVPIGLFGAL
                     SAVWLKGMTNDIYFQIGLVTLIGLSAKNAILIVEFANKRYEEGHPLLEGTIDAAKLRF
                     RPIVMTSMAFILGVVPLVVATGAGAASRNSIGTGVFGGMLAATFLAIFFVPLFFVLIR
                     SLSRGRNRQLPPPGADGPDQPEKERDYQHA"
     gene            52246..53676
                     /locus_tag="PK063_05455"
     CDS             52246..53676
                     /locus_tag="PK063_05455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux transporter outer membrane subunit"
                     /protein_id="HMZ96525.1"
                     /translation="MRSLALVLFSTLLAACAVGPDFNRPEATTPDAFRMAEPGGDAAS
                     IANTPWWELLKDQELQKLIRTALEENKDLKRAAAAIEEFQARLFIAKTDYAPQMNVTA
                     NAPLFGRKSNFLFPGFPNPFNYYLQGNLSWEIDIWGRIRRSNEAARGDLLSREENRRA
                     IVLQLVSGVAEAYFDLLQFDMQLDIARRTLKSWEESVRIAQARLRQGMISKLDADQFE
                     AERANAAAKAAEFERQKVQKENQLSVLLGRNPGRIARGYSLTEQVMPPDVPPGLPSEL
                     LQRRPDILQAEQDLAAATARIGMAKADRFPKLSITGILGVASPHLSRLVANETAFGVA
                     GPGLAGPLLNAQILGFQQRAAEAQARQAVAQYEQSVLVAFKEVEDSLVAVRTVREQRA
                     AQLQQVEALRSALSLANLRYKGGLANYLDVLIAQRNLFEAELALMGTHRLHLVSIVQL
                     YKALGGGWTPEGQLPVSPIASPPEKS"
     gene            complement(54431..54610)
                     /locus_tag="PK063_05460"
     CDS             complement(54431..54610)
                     /locus_tag="PK063_05460"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96526.1"
                     /translation="MSIDVELALVLGLFMIGAVVLAIDNLVYALSKRFSRWMRNRKSV
                     PRTPSTFTSTQKKQF"
     gene            complement(55034..55396)
                     /locus_tag="PK063_05465"
     CDS             complement(55034..55396)
                     /locus_tag="PK063_05465"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96527.1"
                     /translation="MKRSSQTKLLVHCILSDVAMGCAEEGKVFDVGQRGTLRTTFHNL
                     IDGDHLSVKIQLRDERRPVSVHLAKVSWIQGERFGVELLVMDVDERLRLNRFLEAKLP
                     LELEFQDSHTELTIRAAD"
     gene            complement(55621..56796)
                     /locus_tag="PK063_05470"
     CDS             complement(55621..56796)
                     /locus_tag="PK063_05470"
                     /inference="COORDINATES: protein motif:HMM:NF021508.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2235 domain-containing protein"
                     /protein_id="HMZ96528.1"
                     /translation="MILCFDGEWDCPPDPGVWSFSANHSPKQSRTGVQPDSHSATNVY
                     QLYQSILPRSGDGRIQQKWYEPGTTMPWFHRFRDGSFGCGLDRTILQSYAYLAATYDP
                     GDELYLYGFSRGAYTARSLVGLLTLTGLPAPVLLNADHVRLVREAASPHSPSGGVAAH
                     LRECLTRMVTDPDNHVIDEAYRVYRNLQNASQIATGRRKGSSDINVTLLGLWDTVGPL
                     GIPTKALRWLNEHRYNFRDTELSPIVRHACHALAIDEHRADHNATLWTSPPKAAQVIE
                     QRWFAGAHGDLGGTYPDRDLADVPLAWIRQHSMAKGLALESGRIDEKLNMLGPIHDSF
                     SECFVGFRRWIHPRFYRPVMQTGTGTEVLDESVHTRLLHSPAYRPKNEGLNNLLTFR"
     gene            complement(57237..57788)
                     /locus_tag="PK063_05475"
     CDS             complement(57237..57788)
                     /locus_tag="PK063_05475"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96529.1"
                     /translation="MRFIASRLMILVMGLCLLLTGCVHRIHVNPASNSPATITIPAAV
                     QLEVPFLAIEGADHMPGIAMLDWPAKDLRQAIVRYFSERQTFRAIGTDPAELKMVVKA
                     WLTLRAPDRYLYRVHLEADLSHPGHGVFKTYAAEGEALGSSVRWITASDQEPIDEATS
                     QALQQLATQLEQDRDLIMNNFSR"
     gene            complement(57814..58302)
                     /locus_tag="PK063_05480"
     CDS             complement(57814..58302)
                     /locus_tag="PK063_05480"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96530.1"
                     /translation="MAIRSCRTLIWQTPLMLVIALSLAHCSHDIHEKRADTIKGHVES
                     FYDHLKHDRVAAAVRENEAIEQLSTQLGEIVTRRVNQPGTNQIDREWTDLRTANETAA
                     QNWLALGQYLSIKKQYAQSRATYQRVIDTYNGATERTYREQAARAIRDLDILSPPPAA
                     PR"
     gene            complement(58401..60368)
                     /gene="glgB"
                     /locus_tag="PK063_05485"
     CDS             complement(58401..60368)
                     /gene="glgB"
                     /locus_tag="PK063_05485"
                     /EC_number="2.4.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HMZ96531.1"
                     /translation="MDPVRSHSQNAPLGVVPSSAAPAHIGSLLSPEDLYLFNEGTHFH
                     LYDKLGAHPTTVQGVEGTYFAVWAPEAEQVSVFGTFNHWDPDRHPLRPCQSSGIWEGF
                     VPGVGIGALYKFHIRSRNHGAVLIKTDPFARLNEIPPKSASVVWDLNYSWQDHDWMQA
                     RARHNALQAPISVYEVHLGSWMRVPGEGNRSLSYREAAPKLIEYVQRLGFTHVEFLPL
                     MDHPFFGSWGYQTTGYFAPSGNYGTPQDLMYLIDQLHQHNIGVILDWVPSHFPTDEHG
                     LSRFDGSHLFEHADPRQGLHPDWGTAVFNYSRNEVRSFLISSALFWLEQYHADGLRVD
                     AVASMLYLDYSRKEGEWIPNKHGGRENLEAIAFLRQLNEEIYRRHPDVQTYAEESTSW
                     PSVSRPTYAGGLGFGMKWDMGWMHDTLEYMGLDPVYRKHHHRNLTFRMLYAFQENFLL
                     PLSHDEVVHGKGSLLGKMPGDDWQKFANLRTLFGYMYAQAAKKLIFMGGEIGQWREWA
                     HDDSIDWNLLNYPPHQGLQRWVADLNHLYRAEPALHEFDFDPRGFEWIDCQDVDAGTI
                     SLLRHGRSSRESIAVVCNFTPVPRLQYRVGVPQGGYWKELLNSDASLYGGSGLGNLGG
                     LSADAVPAHGRSHSLALTLPPLAVLFLKSAS"
     gene            60530..60607
                     /locus_tag="PK063_05490"
     tRNA            60530..60607
                     /locus_tag="PK063_05490"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:60566..60568,aa:Glu,seq:ttc)
BASE COUNT        11696 a        16926 c        19321 g        12602 t
ORIGIN      
        1 atgaattgaa acgtattcac atgatcggta atcgaaggtt gaaaggcgat gtcatgactc
       61 catggaaacg acaagggtat gcgctcaagt cgggcgaagg gccttcgatt gagtttcgcg
      121 gcacgaagat gaccgtcaaa ctgtccggtg cctcgtcgga ggagtcccat tcgctgattg
      181 aaatggttca tccatcaggc gtgggcccgg cgttgcatat ccatccgacc ggcgccgagg
      241 ccttctatgt gctggaaggc cactacacca ttcattgcgg cgagcaacag tacgaggcgg
      301 cagcaggcga cttcgtgtac gtgccgaaag gcctgccgca tctctatcaa tccggcgtga
      361 acggagggaa agtgttggtg ttgtcgcccg cgggacttga acggtacttt tcagaagttg
      421 ccgaattgtt gcgagtcggc ccggtcacgt gggacgtgga gcaggcgatc gccgcacagt
      481 atggccagga atttctcgac ggacttcgtc actgggggca gtgaaagggt gcgcgacgtt
      541 acggttttcg gcgttcccgc ctagtctgtc ttgtttccct gatcacagga cagcgaagga
      601 ctcaggcggc ctgcatccca tttccaaaac atacagaagt cggtgcggtg cgattcgtga
      661 aagatgtccc ggtagcacac ggtcccatgg tagtagagcg ctgacttggc cgtctgaatg
      721 gccgtgatct cttcggccgt gaatggcgtc tcgcggaccg tttccgttcg cggaaccttg
      781 cccatgaacc atttgcgttt gtccggctgc gaatcgtccg gggggcaggt cacgcgctcg
      841 aaattcttga tcagcgggta gtcggccacg gtgatgaagg cctggatggc atcattgtag
      901 gccggcgtcc gtccggcatt ctggatggtc tcccgaactc gaggcgacac accttccttc
      961 aacgccggtg gccccaacgc gcggacgttg acgtaggcac gcaattcgag tttcgcttcc
     1021 tgctgcgaga cgtattcctg ccacgtcgga tagcccacga aggcgccaac caccgcaatg
     1081 atgaccacag acgcaaagac ggcgagcctg atgtgaaagc tgcgttcgtc agcaggcgtc
     1141 gaattcatcg aaggctcggg gacgagcatg tcaggggagg aagggctact cgggtgatcg
     1201 gcgttcatgc tcaacctcct cgtttcaaga ctgtagcgta gcgattctgg aatgtgggat
     1261 caagcagccc gtgcgcatcc ttccagaaat gtactggatt cacgtgagga gtgactgatt
     1321 gtcgcgccac ctcacatcgc cctatctctg agctgctgaa tcgcgtatcg tcgagagtca
     1381 tgggaatcag tccatcattg cgtggcatgt cagtgatcgt cgcgggggcg gggctagccg
     1441 gtctgaccgc cgcgtacgaa ctgcaacggc gcggtgcgca ggtcacggtg gtggaggcgc
     1501 gcgaccgtgt ggggggccgc gtgtggacga ggcgtgacgg ttttgccgag gggcaacatg
     1561 ccgagggcgg gggcgacatg atcgatcctg accaggagtc catccgccgg ttggcaaagg
     1621 atctggggct aaccctatcg ccgatcctgc gcggcggctt tgccttcgcc cgtcaggcgg
     1681 ctcgcgggcc cgtcatcacg caggcttcca aggcaggtga cctctgggct caattggcac
     1741 aagccgctga gccctgggtg cgagcgcatc ggttgaacga gcgccgatgg gatgggccaa
     1801 tcgcgcggca gctggctgaa cagtctgtgg cggactggct cgactctatc ggggctaacc
     1861 agcagctacg tgcgcggctg aatggcatgc gcggattttt tctggccgac ccagagcatc
     1921 tgtcgttgct ggccctcgtc gatcaactgt ctgcggaatc gtcggcgttg gaccatttct
     1981 accgcattaa aggcgggaac gatcgtctcg ccaccgcact cgccgacaca ctcaacgaac
     2041 cgattcaact aaagaccatc gtgtgtgcag ttgcgcagcg tcgaggccag aggcgggtta
     2101 ccgtgcgcag gggaggtcag caggatcaca tcaccgctga tgcggtagtc ctggcgctac
     2161 ctgccaccat cgtgcgtcgg ctcgccttca gtccaccctt gccgtcccca caacgcaaag
     2221 cctttcaaga tctccagtac ggacctgcga cgaagacgct gttgcagttc gatcggcgat
     2281 tctggcggca ccagggagcg cctctggcgt acggcaccga cctgccgatc ggcgcgatgt
     2341 gggacggaaa cgaagaacag cgggggcgaa gcggcatcct caccttgctg gccggcgggt
     2401 cagcgagtcg tgacacgcag cgactcctgg cccacggcgg tgccgaggcg gtggcggagc
     2461 agctgaagtg gttgggggcg acaaaagccg ttctgtgtgc atcgcatcac gtgtcctggg
     2521 aagacgatcg tttcgtgcgc ggcggctatg cggtgtttca gcccggatat gatccggagc
     2581 aacgtgcctg gctgtcccgt ccgcatggac ggattctctt tgccggcgaa cacaccagcc
     2641 tgcgttggca gggctacatg aatggagccg tcgaaagcgg tctgcgagcg gcgctggagg
     2701 tggagtgctt gctcggacgg ctaaaatcga acgcccactg ataccagcgc gaagttgtac
     2761 cagccgaagg cataccgatc attgtccact ccgccttcga atacccggta tcccgcagtc
     2821 atgaaccaat ggtcggtgag gtcatagcgg acttttagcg ccgcgtcgat cgcacgtcct
     2881 tgtgtgctga cgagcccgtc gaagtcaagc aaagccgtcc agcgcggagc gatgtcatac
     2941 tcgaggctcg tgctgagtag cgggacgaat ccgacgttgc tatcggacgc cacccttccc
     3001 tgttgacgca gttccacgcg cgcatctcgt atgaaagccg tggcgccgat gcgccagcgc
     3061 caacgttccg actcgtgtac gagataccga taggtcaggc ggtaggaatc gaacttgtaa
     3121 tcggaatcga tgggaacacc cggggcaaac gtgccacccg aaaaacgtac cggggaaccg
     3181 aacgaccctg tgcctgaaaa cccgagaggc gcatacacga atcggagtga atgctgatgg
     3241 ctgagattcc acgtgagctc aacgcgccgt tgaacgttag ggccgttgcc ttgaatgtcg
     3301 gtcagatcaa agcgagttcc attgctgtta tcgggaatct ggatctgatt tcgcgattgc
     3361 cacacggcac ctgtttcaaa ttccagcgag aagcgatggt cgggggacct tacttcttgg
     3421 gtgaatccaa gattgggtag acctactgtg gctatgaagg agagccggat cacagccctt
     3481 gccagagcgg cgtgagcttt tcgctgactg tgcgagaatc tacccatgat catcggccac
     3541 tcctttctcg ccgactttca gtcctagaaa ttcgttccgg atcattccgt acaactccac
     3601 gtcaatgcgt tggccgaacc gaagatagtg ctcacgcaga cggccttcgt atgtcatgcc
     3661 caccttctgt aacacgcgtc ccgacgccgg attcgtatga aaatgcggcg cgtagatgcg
     3721 atgcaggctc aggctgttga acccgtattc gactaaagcc gtgacagctt cagttccgta
     3781 gccttggttc caatagtcac ggcccagcca ataagtcagt cgtccctgtt catgtacgag
     3841 catgagctcc atgccgatag agccgatgag ctcgccgttc tccagcaggg tgatggcaaa
     3901 ggttacaccc gttcctgccg cctgatcctt cagacgttcc gtgacccagt cttgggccgc
     3961 ctgccgatcc attggatgtg gaaggaaagt cccggcagcc acgtcttgtg atccggcgag
     4021 acgatgcacg gcctctgcgt cggtcgtttg aaatggccgg agccgcagcc gcttggttcc
     4081 aattgtgacg attgctgtca tgggtggctc tcattatacc gactggacag ccaccactgt
     4141 cggctttcgt cgggattctt gacgctcctc ctgttcgcgg gtagggttac ccctggtgtt
     4201 tccgtaagga gtttcaatgg acgttgcgca ggtgttgatt gccatcgtcg gtttcggggc
     4261 cgcggtgacg acctattgtc tcatgcggtt tccgcatatg cgtcgggaac ccttccggca
     4321 gtatcgaggc tgttcggtgc tggtctcgag tcttgccgcg ctggtggtat tgtgccttgc
     4381 gctggtggta ctgattgccc aatatgcctg gcatgcgcgg taacgaaacc tgcgaactga
     4441 gcttccattc atggccccgc ttcattctcc tcaatcacgc tcatccgtcc aattgtggaa
     4501 cgatgtgcct gaaactgaag caatctgcgc ttcctcaatc tacagaaaga gtgttggtca
     4561 tcttttctgt ggcatcnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnaatc
     4681 tgcgcttcct caatctacag aaagagtgtt ggtcatcttt tctgtggcat caagggttga
     4741 tctgacccgg tcggtctgct aggaataaac gcgacacctg tgcagtcgac cggacatacg
     4801 ccgatccctt cgacggcgag atgagacagt cactccttcg ctcgtactcc cctcactccg
     4861 cgtctcatcg atcgttcccg cccgatccac gggcctttcc gttgtgtttg ctgacatcgt
     4921 tcgtccctca acagcgtgct gaaaccgcga gggatgtttt gtttttgaac caggatgccg
     4981 agtcgaatgg atctggtacg ggccactcat tctttgcaca agcctattcg cgccaaaact
     5041 cgcgcgttcg accatcacgt cgagacgcag gggccgccgg cgcaaaagcc gccgtccatt
     5101 cctgcggggc tcgatcgaac agactggatg tgtgccgccc tcttttccct ggcggtagcg
     5161 atcgcctgcc tgctgatcgc acgagcgatg ccgtcctttc tctttcagtc gatggatttc
     5221 tggttcgagg cagatacgct gcgcgaaatc tcgaacatga cccgcgtgca cgacgaccac
     5281 taccggacgt ccgtgcatcc cttattttct ctgctgacct ttgtcccggt ctatctgatc
     5341 aaacatggat tgtccgtcag cccgctgcgt gccgtgctcc tggtcggcag tctggttggc
     5401 gggctatggg gcggcacgct ctatgtcctg ttccgtttgc tcgggtgccg gaagccggac
     5461 gcgatcgtct tgaccttgct gggactcgtc agcgcatcgg cgctgttctg gctgccggtt
     5521 cccacctcct attcctgggg ctctctgtcc atcatgctgg cgctcgtgct gttgttgtat
     5581 acggagcggc gtccaatcgg agcgagcgtc tacgtggtgg ccagcgcgct gacgttgagt
     5641 ttcaccgtca caaactggat ggcaggacta ctcgtcagcc tggcgcgatg gccctggaag
     5701 caggcggtgc agctttccat caatgcgctg tgcctggtgg tgattctgtg gggcgtgcag
     5761 aaggtcatct ttccgtcggc ggcgtttttt atcggccagc gggaggaagc ctccttcatg
     5821 aaccatcccc aagcaggagg catcaccaat gtggcctcct cgattgtatt tcacagcctc
     5881 gttgcaccaa ccgttcgttt cctgaaggat gatgcttatg cgcaagccaa cgccgatgcc
     5941 ttccgtctct cagagcgtct gacctttcaa ttttccactc ccggctcggg cggcccgctc
     6001 gggctcgtgg ccgtcatcct gtggtcgggg ttactcctca atgggttatg gaggttggtg
     6061 acgctggatc atcacctgcg gttccggctc gtgctgggga gcatgttagc attcgaggtc
     6121 ctgctgcaca tgctctacgg ggaggaaacg tttgtctaca gtttgaattt catgccgctc
     6181 cttttggcgg tcgcggcatg tggtgctctc gctcccggtc gacgcatcgt tacgggagtg
     6241 gccgctgtgc tcgtggtctg tgtcgcgctg aataattggc aacagtttca agccgccacc
     6301 catacggcga cgcagttcac gccccagcgt gagctgatga cagccatgat ggagaaagat
     6361 ccggagcggc cctggcccag gtcggtcgga catgtccccc tggccgttcc cggttcgccc
     6421 gagggaggaa cggcctacca tgagccagga ggagatttca gcccgcaact gcccagtttc
     6481 ggcgtctccc tctggttgtg cgatgcgacc ggtgcgccgg tggttgtcag tcagacggta
     6541 ccgatccacg agatcacaca agaattcgcg ccatccgctc atccgacgat tcccgccatc
     6601 accaccaaaa cgccgtatta tcaggcgacg tggacgcggc tcgatgcgtc ccgctgggaa
     6661 ctccgattca agaatgagac gaaccatgtg ccggtgatcg tgcttcggag cgtggggccg
     6721 gccggggggc cggtgactgc gttgaatcag gaggaaggga aggtgacggt gaaccatcgg
     6781 tgggccgtca ccgcgacgcc cgctcctgac cgcattgcga tgggagacga aaatacagct
     6841 ggttggatga ccgaacagtc ggccgtcacg tcctggagcg gcgaggccgg gtggggatac
     6901 gcgcggctgc aattctcgct gggaacgacg aagccgggcg aagagatccg ggtcgtgctg
     6961 tcagacttgc gccctcccgt tgaaatcgaa ggctactaca aacaggcgcc gaagcgggcc
     7021 cggctcgcgc tgccggatcc gcgcctgcag gcttcgatga acgcccagat cacgcacttg
     7081 atgatgagcc tggtcgatga tgaaacgcgc cccggcgatc ctgctgtgtt ctatcgggcc
     7141 tggcatcgcc aaggcgcgta cattacggcg gcactcgccc gcgcggggga gcctcgcgtc
     7201 agccgggtgc tctcacagtt tctcgcgatg catgattttg caggaggctc cggtccggag
     7261 gccgatgcgc ctgggctgac gatctgggcc ctcactgaat ccgccgacta tatcggcgac
     7321 aaggtgcatg acgagtggtt gtggccgcat attctgagga aggcccggcg catcgaagag
     7381 atgctgacgg cgaaaacgcc gctggtcgag ccgtatacga ttccggctcc gcacgatttc
     7441 aaacatctgc gccaaaccag aacggcggtg ttggcgcaac cggcacgaga agggctcatc
     7501 gtcggccggg tgggtgagga gtggccgtcg ctctacgtga atgccgtcag ttatcgcggg
     7561 ctggttgccg cggccgagtt cgccgagcgg ctcggtaagc gccagcaggc ggcgcgctgg
     7621 cgcacgcagg cgcaggggtt actggagagc tggcagcgac aatctaccca cgacagcatg
     7681 cagggcagcg cgtcaccggt gagtctgcgg gccttggctg atccttcgtc ccgtcgccat
     7741 caactcaagc aattgctgac gacgtatcgc cccactgcgg accacaccac gagtgccgga
     7801 caattgtcgc aggctcatca ggcattgcgg caagggaagc cagaggcggt ctggacggtt
     7861 ttgcatcggc tgtgggggga acaggcgtcc ccgggattgt atacctggga ggcggccttg
     7921 tcgtcgaagg acgaggtggc cgacggatgg caatatgcgc gcggatggca taacgagttg
     7981 gcggtcacgc ccgactacga aacggcggcg ttgctcctgc tcttgcaaca agacatgctg
     8041 gcgtatctcg atgagcaggc tgcggagccc acagtcgtca tcggcgccgg tatcaccgcg
     8101 ggctggttgt cgcagccgat ggcggtctcc aacctggcgc tccccggtgg ttcgatcacc
     8161 tggcaatggg acgggcatgc catgcgcgtc acggtgcgcg gcccggagcg agcggttcgt
     8221 ttgggaactg cgtttccccc cggtacctcg ttgatcgtca cgcataaacc ggctattcac
     8281 tgaagcgtga gtatttcttc cacggacgcg gttgtgcgcc accagcgctg gtgccgtcgt
     8341 tctgctatcg cccaccctcg catccatcct cccgacgggg tacaatccgg tcaatgccga
     8401 gcgctcacat ggctaccacc accgaaccga ggagtgttgc cgatgttgaa accggaaccg
     8461 gccggggggc cgaccccgca gttattcttt cagacggcca atgcctatca acggtcgcaa
     8521 gcgctgaagg ctgcggttga actcgatctc ttcaccgcca ttggactggg ccatgatcag
     8581 gtgccggcac tggctcagcg ttgcggtgct gccgagcgcg gcgtgcggat tctcgcggat
     8641 tacctcacca tacaaggatt cctcaccaaa gagggcgatc ggtataagtt gacgccggac
     8701 agtgcggtct ttttggaccg tcgctcgccc gcctatatgg gctctgtctt ggggttcctg
     8761 catgcgccca agttcatcgc cgcatttgag catttgaccg aggcggtgcg gaagggtggc
     8821 acggtggccg gcgaggcggg aacggtcgcc ccggagcatc cgctctgggt ggactttgcg
     8881 cgttccatga tccccatgat ggccaagccg gccgaggaga tcggcatctt cgttcggcag
     8941 tcgcagccca acgtgaaaaa ggtgttggat atcgcggccg ggcacggtct cttcggcgtc
     9001 gaaattgcga gccgatgccc gcaggcagaa atcgtggcgt tggattggcc caacgtgctg
     9061 accgtggcca gggaactcgc ccaacaggcc ggtatcgcat cgcgctatcg gacgatcgcc
     9121 ggcgacgcct tccagcagga attcggcgaa tgctacgacc tcgtcctgct caccaacttt
     9181 ctccaccatt tccccgtgca gacatgcgaa tcgctgctgc gtaagatcca tcgctcgctt
     9241 gcgccgggcg ggcgcgtcat tacgctggag ttcgtgccgg atgagaatcg cgtcacgccg
     9301 ccgcccgtgg cggagttcag cctgatcatg ctggcgacga cgccggaagg cgacgcctat
     9361 acgttccggg agtatgagca gatgtttgcg gcggcgggat tttcccggac ggaactccac
     9421 ccggtagccg ggtcgatcga gcaggtcctg gtgtcgactc tgtaataggc cttccatgag
     9481 tcgcgactca cctcacgacc ggcaccggtt gatcatccac cggtgccggt ttgggtctga
     9541 cccctactgt ctctaaggtg atcggcagca cctgatccgg cagagtgttt caatcagata
     9601 agcgtacccc ccttcgacat cactgcagac gctgccggta ttcctcaccg tacagatcta
     9661 ttcgcgaccg ctagggtttt gggaatccct ctggcatgcc cggtcattgt ctaatgaagc
     9721 ggttggtatg atgatcgaat gagcagctgg acggggactt gccgatgagc gacctcattc
     9781 gtttgcagcc ggaagggctc gtgggaccgg gcaaccgttt ccatatcgac gcctgggggc
     9841 aggctgccgt caatttgatc acccatgccc atggcgacca tgccaggacg gggagtgccg
     9901 agtattggtg cgcggagccc tgcgcgccga ttctccggca tcgtctcggc ccggacctcc
     9961 gtattcgagc cgtgccctac cgcaagccgg tgcggctcga tgattgctgg atttcatttc
    10021 acccggccgg tcacatcctc ggctccgccc agatacgggt ggagcagggg tctcgcgtct
    10081 gggtcgtcac gggggattat aagcgtgacg ccgatcccac ctgcgaactc tttgaaccgg
    10141 tgccctgcga cacgatgatt acggaagcga cgtttggatt gccgatctat cgctgggcct
    10201 cgacccgttc tgtgacgggg cggatcgtcg actggtggca gcgatgccgg gaggagggag
    10261 tcacggccct gctgttttgc tatgcgttgg gaaaggcgca acgcatcctc gccgagctga
    10321 cgcacttcac gcaggaggag gtcctgctgc atggggccgt ggccgcactc acgcagattt
    10381 accgcgaaca aggcgtctcg atggttccga ccaggctggt gagtgacgca gaaggtccta
    10441 ccgaagggcg gctgatcctg gcgccgcctt ccgcccatcg cagcccgtgg atgaagcggt
    10501 ttcgtgccgt gtccacggca tttgcgtccg ggtggatggc ggttcgaggg atccgtcgcc
    10561 ggcgtggcta tcaccgcggg ttcgtcctgt cggaccacgc agactggaaa agtcttctcg
    10621 acacggtcga agaatcgcgc gcgactcgtg tgttggtgac gcacggcacc tccgacacgc
    10681 tggctcgata cctccgagac gtcaagggag cgaaggccga agccctgacg acccacttcg
    10741 gcgagggaga agactagtgc aggcgtttgc cattctgttc gagcaactcg atcagacgac
    10801 cgcgacgaac gaaaaggtgc ggatcatgac ggagttcttc cgtcaccagg atcccgacac
    10861 cagcgcctgg gtcctgttct tcctctcggg tcaaaggccg aaacagatcg tcgggtccac
    10921 caagctgcgg cgttgggcgc aggagaaggt cggttatccc gattggttga tggaggaatc
    10981 ctatgcagcg gtgggcgata cggcggagct gatcgccctt gtgctggctg cgggagaagg
    11041 agccgtcaag cacgcgccgt tgtctcgact ctcgttgggg gagtggatgg tccagcgcat
    11101 tttgccgctc gcggggatgg acgatcaggc tcgccgctcg aacattctcg cgtggtggga
    11161 agagctcgag accaatgaga cgttcatctt gaacaagttg ctgaccggat cgttacgggt
    11221 cggggtgtcc gaaacgctcg tgtatcgcgc cgtggccgcg gcgttttccc tgagtcctgc
    11281 ggtgattgct tcccggcttg tgggaacctg gcaacccagc gccgagttct ttctccgtct
    11341 tagtgcgccg gcggaagaga ctcagaccgg gcagaggtcc gacgagaccc tgttaccact
    11401 tcccttttgt cttgctgctc cgatggaggg tgatccggag gaactgggag atatatcgaa
    11461 ctggcaatgt gagtggaagt gggacggtat ccgctgtcag gtcgtgaaat ccggctcgcg
    11521 cctggagatc tggtcacgcg gcgaggagcg gatcaccggc tcctttcccg acctgtcgcg
    11581 actcctctcg ccggtatccg gcgactgggt tatcgacggc gagattgtgg caggggattg
    11641 gcatcgtccc gatgcgtttc aatctctgca gcggcggttg aaccgcaaaa aaccctcgct
    11701 ggcgctcatc gcctccagtc ctgtttcatt cttggcctat gacctgcttc aagccgatgg
    11761 acggtcatgg cggcaccatc cccttgcaga acggcaggcg atgcttgaac gcacactgca
    11821 tccgtacatc ggggagcgtc tggggatcag tccgctgctg gcgctgtcat cgtgggagca
    11881 ggccagactg ttacgtgaga cgtcgcgtgt agagggcgcc gagggactca tgctgaaggc
    11941 gaaggacagc gagtatgtga ccggccgcaa gcgcggcgtg tggttcaagt ggaaaatcga
    12001 tccgctggcg atcgatgccg ttctgaccgc cgcccagccg ggaaccggcc gccgcgcgtc
    12061 gctgtatacc gattacacgt ttgctgtctg ggcgggcgat agtctgatca cagtcgcgaa
    12121 ggcctattca ggtctcacgg acgaagagat tcgcgaactc gacggctgga ttcgcaagca
    12181 tacgcgcgag cggttcggcc ctgttcgcat ggtcgaggca cgccgcgtgt tcgaaatcgg
    12241 tttcgagggt atcagccaga gcgaccggca caaatccggg ttcgcgctcc ggtttccccg
    12301 gattctgcgc gaacgaacgg acaagcgcgt ggaggatgcc gaccacgtcg cgacacttga
    12361 aacgctgctc gcatccttcg gttcgtcggc tggccggctg ggacgcgcca gagcaagggc
    12421 ggagtccctg ccggggcagg agcagctgca gttcgaactc ggggctggag atgtcggttc
    12481 atgagtagct cggcgaaagt cctgcgaggc atccagcggc tcaaccggat ggggccgctg
    12541 cgtccacggc ccgatgctga ggaacaagcc cgtgctcgtc gaaaagcctg gccgacgctc
    12601 tcacgcgaag aggcgtggaa acaatggaac gagtggttcg atcggcaagg atggtcgccg
    12661 tttccatttc aagttgaggc ctggcaggca tttgacgcgg gacgctcagg cctggtcgcg
    12721 gtgccgacgg gcagcgggaa gacctacgcc gctgttggag ggccgctcct gagcctgatc
    12781 gcccatccga tagctggcca ccagccgcca ctcacgattc tctatatcac gcccctcaag
    12841 gccctggctc gggacattgc gcaggccatt caacagccgt tggacgatct gggctggccg
    12901 atcgatgtgg atctccgcac cggcgacacg accgcgacgg cgcgccggaa attcaaagaa
    12961 cgattgcccc atgtcctcgt gacgaccccc gaatcacttg cgatcttact taccgatcaa
    13021 gggtggaagg atcggatgcg agctgttcag gcgatcatcc tcgatgagtg gcacgaactg
    13081 ctgggaacga agcgaggcag tttgctggag ttgacgctcg cccggttgcg tgcgatggcc
    13141 gccggagccc gggtgtgggc cctgtcggca actatcgcga acttggagga agcggcgtcg
    13201 atcgcggtcg ggagcggcct tgagccgacc atcatccgtg cggacattcc acgacacatc
    13261 cggattcact gcctcctgcc ggagtccatt caacgttacc cctggtttgg ttattcggga
    13321 ttgagtctgt tgccggaagt cgtcaggcag atcaatcccg atcaaagcac gctgctgttt
    13381 actaacacca ggtcgcatgc cgaacggtgg tatcaggcga tcctcgaagc caggccggaa
    13441 tggtcgaccg tcatggcctt gcaccacgga tcgctcgatc aggacgagcg gcagcgcgtc
    13501 gaagatggca tcaaaagcgg cgccttacga ttggtcgtcg cgacctcttc actcgacctc
    13561 ggggtcgatt tcccgccggt tgaaaatgtc atccagattg gatctgccaa atcgatcgcc
    13621 cgggcggttc agcgagccgg tcgcgcgttt catcggccgg gagaggacac gctggtgcag
    13681 ctctgtccaa ctaatgtcat ggagattctt gaggcgtcgg ccctgcggca aggcatgcag
    13741 ggtggcgtct tggaggaacg gacgccgctt gaaaagccgc tcgacgtgct ggtgcagtgt
    13801 ctcctgaatg cctcattcaa cgagggcttc gatccagccg atctctgccg gcaagtccga
    13861 tcggctgtct cctttcgaac cgtcacggat gacgaatggt cttgggcgtt ggcattcatc
    13921 cgttccggag gagccctgtc ttcctatcca gaattccgca aggtcgaagt ggtcgagggg
    13981 cgctatcggt ttgtttcgac ggaggcggcc cggcggcaca agatgaacat cggcacaatc
    14041 ctctccgaca gcggcgtgac ggtacaggtc cgaggaggag ccagactcgg catgatcgat
    14101 gagacgttcg tggcgaagct tcgacccggc gatgtcattc agttcggcgg ccgcaccgta
    14161 cagtttctgc agatgcggga catgaccgcc tatgtgaagc cggcccgtca acggagtccg
    14221 gtcgctgcag tctggagcgg caccattctt ccgctcagcg tgcaactgtc tttctacctc
    14281 cgccgagagg ttgaccgcct gaggcaggcg gtggaagggc tcaatccacg gtcgcccgag
    14341 attgatgcgt tgctgccgat cgcgcgtctg caatccagcc ggtcacgtat tccatccacg
    14401 gcgcagacgc tgatcgaaac ctgccggact gccgaagggc atcatgtgtt cgtgtacacc
    14461 tgggaaggct ggagcgtcaa cgaagggctg gggcatctgg tggcctatcg tctgtcgcgg
    14521 ctgcgtccga acacgattgc tgtctcggcg accaactacg gcttcgagtt gctctccacg
    14581 gaaccgctcg gcagtgaccg tgagatcggt caggcgctga ccactctcga cgggttggag
    14641 gaggacatcc acgcgtcgca gaactttccg gagctcgcga ggcgggcgtt ccgcgaaatc
    14701 gcgcgggttg cggggctgat ctaccagggc actccgtccg cgaggaaaac ggcacgtcat
    14761 ctgcaaatga gcgcctcgct gctgttcgat gtgtttcgac agtatgaacc gtctcatccg
    14821 ctgctggcgc aagcgtttcg tgaagtccac gatcgccagt tgcagatcga ccggctgcgc
    14881 ggcctgatgc gtcggatggg cgagcaggag ctgttgatcg ttcccatccc gcggctgaca
    14941 ccgtttgcct ttcctctcta tgtggagcgg atcaagtcgc gcctctcgac cgaaaagctc
    15001 gaacagcggg tcgcgcggtt gcaacgggag gtgtttcgct gaatgagaat ccgtatccga
    15061 gacgaatgtg tcgccctgct tcccgaacgg gcgatgtttt ggccgaccca ttcgctgctg
    15121 gtcgtggcgg attgccatct cgggaaggcg gagacttttc aacagcaggg attgtggttg
    15181 ccctcgcagt cgggacaaca ggaccttaca cgcctctctg cgctcgtgct cagtgttgac
    15241 gcacagcacg tcctgttctt gggcgacctg gtccattcgt tgagcggggt gactgacgcg
    15301 gtcgtggcag agttcgcgcg atggttgcac gagttcagcg ggtcggtccg ggtcgtgctg
    15361 ggaaaccatg atggcggact cgctcgccgc tggccgaagg aatgggtgaa ggcagagcgg
    15421 tgtgaccagg tgaccatcgc tccatttcgt ttcaagcacc agccaattga gggaaccgtc
    15481 gaggcagaca ccttttattg ggtgggacat gtccatccga tgattcaatt ggcgcaaggc
    15541 ccggaccggg tgaggctccc cgcctttgtg atcaatgacc gacaaggtgt gctgccggcc
    15601 ttttcatccg tcagcggcgg gtatgacgta cctctgcgtc ctgacgagcg gcggttcgcg
    15661 atcggtggcg atcgaatcta tgagttgtga cctttcgatg gagagggcat gccggcctca
    15721 aaaccgttcg cgctcctttg aggcgagacc atgccggctt acccgtgcgt gtcgaactag
    15781 ggtttttgag aggcacgttc ctcctggcgt cgttgttaaa tggcgcagag gtcgccttgc
    15841 ataggcgacg aaaggagggc cctatgcggt acgtcattgc catcgtggtc atgtgcctgt
    15901 ccgttgccac aaccgtccag tatgccgacg ctcgggatcg caacggagtg ttcaaggcca
    15961 gtgaactgat cgggatgaag gtgcagggaa cggacggaaa gaatctgggc gacatcaagg
    16021 atctggtgat caatcccgat gacggagcaa ttgattatgc ggtcctggac ttcggcgggt
    16081 tcctgggcat caaagacaag tatttcgcca ttccctggga tgcgctgcag gtggcatcgg
    16141 gtaaagacaa gattctcatc gacgccacaa aacgggatct caaaaacgcg ccggggttcg
    16201 ataagaacca ttggccggat ttcggcgatc tggcgcagac caccgtcatc tatgaatttt
    16261 acggggttcc ggcacccaac acgagcgggc agcacaaggc gaccaggtga catgcaggtg
    16321 cagtgacagt gcggccgcgc gttaaaaccc gcggccgcct ccgccgccga atccgccgcc
    16381 cgatgatccc ccactgctga atcctgatcc gccggagctt cggggagcgg atgtcatcgt
    16441 cgagccggtt cgtgacgcca ggtcacccat gcggctcgtg aatcctctcg tattgaactg
    16501 cgtgagatcg ctgccttggt accaggccgg agcggtcatg acgatcgttt cgaatgctgc
    16561 cgcccaattc ttttcgactc cgagcgccat ggcatagggc agaaatttct cgaacagttc
    16621 gggcgtcttg atgacgcgat caaaccggtc ggcttcgacg cgcgtgagaa attcctcaaa
    16681 ccccagcacc ccttccaacg cccgtgtgcc ttgctgtgtg cgagccggca tgatgcggcc
    16741 gaatccgatg acaatcatcc ctgaaagcaa gccggccacg aagactgtga gtggcgcgag
    16801 gccccaccgg tcagcgagga tgccaagccc gatggtcagc agcattccga aggcaatgcc
    16861 gccgatgaga tatccctgtt tcacccggtc ggggcgctgg ctgtaatacg tgcgtttttg
    16921 cagggactgg aatatcgcgt cgtgtattcc tgggagagat ttgtagaagc ggttttcgag
    16981 cgagctgagg agaatctcat cgacttcgct atccttgaac agagcctcca gcaagagccg
    17041 ctcgaaggac ggtaaggccg cccattcctg ccgtggcttt gtccgctgaa acgcataatc
    17101 catgctcgac cagagcccga acagatgttc ggccttgcgc tcgctgattc gcacatagcc
    17161 gcgcacggcc aggtccacta cggtggcggt gatatcgcgg gtgtccggac tttcatccac
    17221 cagtgtcccg gcttctgccg gtgtcagctg gtccggtggt tcgtacatga cggcaatcgg
    17281 ccggagtcgc ggatcttttc ccctggtgga ccagaggcga tacatcacga ggaacgcgag
    17341 tagagggatg cccaagggcc aattgctgac gagcgtcatg cgggtctgct ccaccacggt
    17401 gggggcggcc acgaggccct tgtcccaccc gacgacggcg gtgagtcctt cccgaaagcc
    17461 gagggggcgt gtcatccgca tctcgatccc cgaaccgagg atcgtcacgg tcgctgcctg
    17521 ttcgcgcgcg ccataggctc cggtgaaggc ctgggcacgg acgccggtcg cctgcggagg
    17581 aaggaggatg cgtacggaag cctgctcgat ggggacatcc cactcgtcgc cggtgacgtt
    17641 ccaatacagc tcgtcatggt cctcgaaaaa tttcaggccg ttccggacaa ggtatttcag
    17701 cacgaaggtg cgggtggcat ctgcggcgcc gggaatccag atccggaggt tccggtaatg
    17761 ccgctcccgg ctgctttcga atttgagcgg ggtgccctgc tcgtccgtca cggagatgcg
    17821 atccagaaac agagtgtagt tgaacccttg cggagtacga tattccacgg gaatcagccg
    17881 ctcgataccg ttccaggcgc cttcgaagcg cgggctgacg gtttccgtca cgagcaactc
    17941 gccgccggac aacacttgca gctccacatc gaaacgactc agcacaaagg aacgcgcatc
    18001 agccggcagg aggctcacgg attcaatgag gcacaggaag atcaggctgg agagaacgtg
    18061 gacgaaatgt ggacgtcgtc ggggtttcac gatcggatcg ccggcacgat ccacgctaga
    18121 actgcacccg tggcggctca cgctgggtgg tttcggttaa ctcgaaaaac tggcggccgg
    18181 caaagttgaa ccagccggca atgaaattgg tcggaacctc ctgcctcttc gcattgtaat
    18241 cgcggacgac agcgttgtaa tagcgcctgg cattctgcag cgcgtcttcc acctggttca
    18301 gactgccctg gagttgattg aaagcctcga cggcgcgcag ttgcgggtac gcttcagcca
    18361 gggcaaacag cgacttcagc gattggctca actgattctc ggcgacggcc ttggcttccg
    18421 ggccttgggc cgacatggcc ttcgcccggg cagtgatcac ggcttcgagc gcgccctttt
    18481 cgtgcgccgc gtaagccttc acggtttcga caaggttggg gatgaggtcg tagcggcgct
    18541 tgagctggac atcgatatca gcccaggcgc tttcggccgc ggctcggagg cggaccagcg
    18601 agttgtacat cccgatgacg accagcacga gcgcaaccag cacggcgagg atgatccaac
    18661 ccatcggcgt ctccttgcgg atttgggtga aggtacgtat ggaacttcag ggatgatacc
    18721 gtgacccctg caatctgtaa aggatcgcgc ggccttcctg caggggggca tcgcggcttg
    18781 gataggctca gatccggtgc caggcaatcc cgtgacggtt gcgtgacttt ccacgcctct
    18841 ccgggtatcc tccacggcac cggatggcac tcgaacgact atcacgtact cttgcgcagt
    18901 tcactcacaa agatttgagg agggttcgta tggtgcatcg taacggacga atcggcttgg
    18961 gcctggtggt cctgctgtgg tgtgtcttgg ctggagggac tctcgcggtt ccgttgacca
    19021 gggctgagga gccgacgatt gagttcaata gtccggacgt gttgcgtcag attctggaac
    19081 agcaggtcgg caaacgggtg aaggtcaggt tgctctcggg tcaggatgtg gacggcaagg
    19141 tggccaaagt cggcacgcag gcggtagccc tgaccgaact atccgggatg gagttcttcg
    19201 atgcgaccat ccggctggat caggtggcgg cggtgattgt gcggcgcggc aagtagtcgc
    19261 ccatcacatg gtcgattact aattctgcca tctaggctaa ggaaacgatg cctgtcccca
    19321 tcctacgcag aaccgtcgac ctctccggct ttccagacct cgtcgtcatc tatctcggca
    19381 tgcgggtcaa ccgctggaca gggctgaaga ccttattcgg gttcggtcct caaatcgccg
    19441 catcagtcga cgctcagccg gagggactgt tgcttcatga atcactgctc tggtcgctga
    19501 tgccgccgca cgttggaatg cggcaatatt ggcgcgactt cgatgcgctg gaacgctggg
    19561 ctcgttccga tccccatcgg cagtggtggc agcagtttct gcgtgatacc ggcggaacag
    19621 gattctggca tgaggcctat ttcatgcgcg gcgggatgga ggcggtctac aacgacatcc
    19681 tgcaggacat cgggttcctg cggttcgcac cgattcggcc ggctaagggg gcgcagttta
    19741 ccgccagaag tcgagccgga cgaaccggtg aatcggcgtt accaccggcg gtgttggaag
    19801 aggacctgga tcgatgacaa ctcaggtgtc aggaggctcg taggccgtcc tcacgcgggc
    19861 ttttccgaca ggataatctt gacggaagtt tcgagggcaa atcgcccgcg cccacgcggg
    19921 acaagtcgca catcggggca tttctgctcc agccgtttcc gcaacagaat caatctggtt
    19981 tcgaagttat ctttccattc aggcaggccc agccagctat ccatccgcag ctcgcgattc
    20041 gtgaactcca ctcggtgttc atcctgatgt tgtttcagga tccgccagag aatacgtccc
    20101 ggcacgttct tgatgaggta ttccccatcg acgaagatgc agtcatcagc ctggtagaag
    20161 cagaacgagc ggtgcgagag cggtgagtgg agcggcggtg ccgctgcggc gggggcctcg
    20221 actgccacgg agtcgtccgc ttcctgtgcc gactgctcga tcccggcggc cagatggccg
    20281 gccacaatgg ccatcaccgc ctcttcgcga atcaggagcg tgagcggctc caaggattca
    20341 gcgaccaaca cgccgaggca gcggtgtctg atgatcagcg ggaccgcgat ctgtgtggac
    20401 gcattggaga ggccggggag aggaatttcg cggcacaggg attctgggcc ggagagcgct
    20461 tgggcacgat cacgtaccgc acgggcataa cgaagggtgt agtcgaggcc ggaaagccgc
    20521 agcggcagtt tcgccgccgc caccatgccg atgaggcctt cgccgaaacc gacctcggag
    20581 ccgaccccgt tctcgtcata gccgcggctt gcaatggtct ggagtgtgcg gcgtttctca
    20641 tccacgagta gcagcatcgt gtggtgcagg ccgaagaact catccaggca gcggagtgcc
    20701 gtctccaaca gttcgccgag gcattccgcc cggttcaact gttccgcgac cactctcaag
    20761 gcatgcaggt tcggatcgat gaacagggag ggcggtcgct cgtcgtgcgc cgggacaggc
    20821 cacgaggtga agccgtccac ccgctcgata tgacgcacgg cgtaaatgtc ggcggcgcgc
    20881 aggcggaaga cgtccgacat gccggcatgg gaggcgatgg cctgcagttg cagagacatg
    20941 gcttgaaaca aaggtcccga ggattccgat cgctcataag tgagcgaaag ccgataggcc
    21001 tgcatcgcgc gagggtcgag gaccatcacg gaggcgaagg gatgctcggc gatgttcttg
    21061 cgcgtcttgt tgaagaactg aaacgaaatc gcgacgtgct cgggatcgac gtaatgcacc
    21121 tggctgacat agctgatgtt aggcgtgccg tctttggcgc aggtcgcgat ggtggccggg
    21181 atgatgcctt cgaagcaggg ccagagatct ttgagtgcca gcgcggcagt gcccatgcct
    21241 cacacctgtt cgccggcgcc agggccggga gtttgggcga agacgccggt gacctgcatc
    21301 tcgattgcaa cggcgggctg catgatgagg gcgtcggtct gctcggccgg cacgccgacc
    21361 gcaatgagtt cgcccagaaa cgcatggcgc cactgctgtt gtcgctcgta atcctgtgga
    21421 gtcgcctgac ggatctgcgt gacgctaccc ttgagctggc aggtgacgtg gtccgtgggg
    21481 cgtgagcagg taatcgccat gagcccgttg tcacggaggt tggccagcgt acgggccgat
    21541 gctggttccg tgagtaatag cgtcacggtc gtacgattgg ctgctaccca gatgccccag
    21601 cctctggtgc attccggcat gaaattctta tcacgtgtgc cgacgttgac ggagacgccg
    21661 gtctgcagca gatcgacgat ggcaggagga atcattgcag gcgtagtggc atcacattag
    21721 gaaaaattta gggacaccat agcatattct taggaaggaa gtcggcgcct cccgtgatac
    21781 gttccctccc gacagtgctg gtgttggaac gcagtccacg atcaaggagg atgatcatga
    21841 agagccatat acttctttca ctgtgtctgg ccgtgctggc cgccacgcct ctcaccggac
    21901 aggcgcaggc agcgcagccg gggaacgtca cgatcaccgc gaccgactat ggcttcaaaa
    21961 gcccggagca ggtgccgtca ggcctgaccg ccatcgaggt gatcaacgaa ggcgctgaag
    22021 tccaccatgc gcaacttgtc cggttggctc cgggcaagac gccggccgac ttcgccgcag
    22081 caatgaaggc cgatccggag catccgccga tctgggccac ttttgtcggt ggcccgaatg
    22141 ccgtggttcc gggggatcgc gcgactgccg tgatggacct gcaaccgggg caacatctgg
    22201 cgctctgtct tgtcccgaac aaggccggcg tggcgcatgt ggcgatgggc atggccaggc
    22261 cgttcatggt gacggagacc atcgggaccc gcatcgctga gccgaagccc gatgtggtca
    22321 ttaccgccag ggattttcag tttgtgttgt ccaagcccat caccgccggg tcgcacacca
    22381 ttcaactgct caacgaaggc agccagactc acgaggtcgt gctggtgaag ctcgcgccgg
    22441 ctgccacggc gaaggacttc atcgcggcgt tcgaacctgg cgctgtcggc cctccgccgg
    22501 ggcggccgtt ggggggcatt gtaggaattg aacaggggag ccggggtctg ttcacggcca
    22561 tgttcgatcc agggccctat gccttgatct gcttcttccc ggataagaaa accggcgcgc
    22621 cgcatttcgc gcaggggatg acctgggaat ttgatgtgcg ctgatggttc acgcacgaac
    22681 gggcggggcc gcctcgcggc agttgcatcg gaggccggat ggcaccgtat actatgccca
    22741 tgcatgacat gatgccgagc actgttgaac cgatgatggc cgatcgtggt gcggcgttgc
    22801 tgcaggtggc agaggtcatc gctgcgcacc acgatttgcc gtcgctcttc caggacctgg
    22861 cgcaatgcct gcctgtggtg gcgccattcg atttcgtcgg gctggtcctg cacgatgccg
    22921 ccaagcacgt gatgcaggtg catgtgctgg aaacggcgga agcgaaacgg gtgacgcgcc
    22981 gtctcgacgg gctggagatt ccgatgaagg actcggccag cggatgggtg tgggagcatc
    23041 aacaaccgat tctgatcccg tcgctggcgg ccgagtcgcg gtttcaagtc gggatggacg
    23101 ccttacgggg aatcggcgtc caatcagtct gcttcttccc gctcactacc gcgatgcgcc
    23161 ggctgggcgc catcggtttc ggctgcctga agcccttcgc tttcgacgaa gggactgtct
    23221 cctttctgaa tcaggtcgcc aaactggtgg cggtcgccgt ggacaatgtg ctgcatcacc
    23281 aggatctcgc ccgcgaccgg gaccgattgc gcctgctgct cgaggtgacc gagtcgatcg
    23341 cgtcgcatca tgatcagagt ctgttgttgg ccgacctggc taagcggttg ccccaggtgg
    23401 tgccattcga tttcatgaat gtcgtccgcc acgacccttc gcgtgacgtg atgcggctgt
    23461 ggctcctggt cacgtctgag cagtccacca tcgaaccggg attggaaacg cccgtcgacg
    23521 aatcaccggg cggcctggtg tggaagacac aagaaccgtt gacggtggac gacgtcgagc
    23581 gggagccacg gtttcccgcc ttgatgaccc tgtttcgcgc gaacggcgtg cgttcgtttt
    23641 gtgtggtgcc gctcaccact gcgcaccggc gtctgggcgc gatgggattc ggaagtttgc
    23701 ggccccgggt ctatctcgac agcgagatcg ccttcatgaa acaggtcgcg cagcaagtgg
    23761 cggtggcgtt ggacaatgcg ctcaactcgg agagcacgct ggcctatcag tcgcagttga
    23821 ccagggaacg cgatcggcaa cggctgttgc tcgaggtgaa caatgccgtc gtctcgcatc
    23881 tggatttgga tcagctcttc ccggcggtca gcgcctgcct gcgccgggtg attcagcatg
    23941 acgggtccag cctgttgctg tgcgatgaag aaaccggccg gtggcgcatc catgtgctgg
    24001 atttcgatcg aaacgaaaat ttcattgaag aggggcgtat cgaggagacc acgcagtcgc
    24061 cctcctgcct ggcgattacg accggtaaag cggccttgtt caatgagcgg gatctgctgg
    24121 ccatgggagg cgcctcaccc tgtgcgcagg atttgctgga tcgcggcatc aagtcctttt
    24181 gctccgtgcc gcttctctcg cgcaatcgtt cgatcggcgc gttgaatgtt ggacggcggc
    24241 gggacgcggg gttcgatccg gaggacgtgc agttgcttgg ccaggtcgcg caacaaattg
    24301 ccatcgcggt tgaaaatgcc ctggctttcc gtgagatcgc cgcactgaaa gacaagttga
    24361 ccaaggaaaa agtctatctc gaagaagaaa tccaaacgga ttacaatttc gaggaaatcg
    24421 tcggggaaag ccgcgcgctg aagcgggtgt tgaaccaggt gcagaccgtg gcggccactg
    24481 attccacggt gttgattctc ggtgagacgg ggagcggaaa ggaattgatt gcccgcgccc
    24541 tccacaatct gagcgctcgc cgagaacgga cctttgtgaa gctgaattgc gccgccatcc
    24601 caaccggcct gttggaaagc gaactcttcg ggcacgaaaa gggcgccttc accggagcca
    24661 tcgccacgaa gatcgggcga ttcgaattgg cggaccgggg gacgattttt ctcgatgaag
    24721 tgggggagat cccgctcgaa ttgcaggtca agctgctgcg cgtgctgcag gagcaggaat
    24781 tcgagcggct gggtagcacc aggacgatgc gggtcaatgt ccgggtgatc gccgcgacga
    24841 atcgcgacct gagtcacatg gtggacgcac aacagtttcg cagcgatttg tattaccgct
    24901 tgaaagtctt cccggtcacc gtaccgccgc ttcgcgaacg agtcgaagat attccagtgc
    24961 tggtgcggca cttcgtccag aagtttgcct cgcgcatgaa aaagcacatc gaaacggtgc
    25021 cgaccgatgc catgcgggcg ctgcaagcct atggatggcc aggcaacgtg cgtgaactgg
    25081 aaaacttcgt cgaacgggcg gtcatcctgt catccgggtc ggagctgttc gtgccgactg
    25141 cggaattaaa acgtccggtg tctccgtcca acgggtcggc cacgacgctg gaggatgcgg
    25201 agcgcgacca catcatcaaa gccctgcggg acacccactg ggtcatcggg ggatcgtccg
    25261 gcgcggctgc ccgcttgggc atgaagcgca cgacgctcca gtccaagatg cagaagctcg
    25321 gcatcgtccg tccccaataa ccgaacctcc gactcgtccc ctttcttctg tctgtgccga
    25381 tcagtcgaca tctgccgaga tgtcggcagt cactcctcgg caccggcacc tgttttgatc
    25441 accgtctcac ggctccttcg ttggaatcgc ctttcgccgc aacgaattct cgttctcggg
    25501 cgcggctcct cggcctggaa caaatcctgc tgtgagcctg actgtattga gatcggaaga
    25561 accggaagga gcggctgatg gaatcggtga ctgagttgtt ggagcagcat ggagcgtggg
    25621 tgttgttcgg tggtgtgctg gccgagcaac tcggattgcc gtttccggca ttgccgctgc
    25681 tcgtcgcggc gggcgtgttg gtggggaccg gtcacctctc ctggtccggg gcgttgatcg
    25741 ccgcgctgtc ggctaccctc ctggcggata tcgtctggtt tcttgccggg cgctggcggg
    25801 gccgtccggt gctgacgctg ttgtgccgga tcgcgctgga gccggacgcc tgcgtgcggc
    25861 ggacggaaga ctttttccgc aagcatggcg tgcaatcgct gttggtcgcg aagttcattc
    25921 ccggattgag cacgatcgcg ccgcccttag ccggaattgt cggcctggga cttccggtgt
    25981 tcctgctcta cgatgcgctg ggtgctgcag tgtgggcggg gtccgggttg gggttcggcc
    26041 tgctcttcac tgaggaggtg gcgttggccc tgacctattc ggaacaggtg gtaccggcac
    26101 tcctgctcgc agcagtggtc ctgctgcccg cctacatcgg ctggaaggcc tggcatgttc
    26161 gccgccaact tcaagccgtt ccgaggatga cggtggcgga tctgctggac aagttggcag
    26221 cgccggatcc tcccttgctc atcgatgtgc ggacgcggct tgccgttgag gcagagcccg
    26281 gtcttcctaa tgccctgcag atgtcccttg aggatttggc gcggcggcat ggggaacttc
    26341 cccgctcccg cgatctggtg ctctattgcg cttgcccggc tgatgccgcc agcgcacagg
    26401 gagtgatgct gttgcaacgg aaaggcttca cgcgggtatg gccgctggcc ggtgggcttc
    26461 atgcgtggcg ggcgatcgtg gacgggcctg aaccggtgcc gatgatacag gtggagagac
    26521 tggcagtctg acgcgcaata cactcacgtc ggcagggagg catctgatgg aattcacaat
    26581 gcccacgacg gagcaggccc attggggatt acgcgccatg aaaaccgtgg cgctggcgga
    26641 cggtgtggtc gatgaatcag agcgacatat gctggaagcc gtacagcgcg tgttcggcac
    26701 acatcatgac gtggacggcc tccaaccact tgcgccggag gagttggcgg cagggttgcc
    26761 cgatcagcag atccgccggc aactcgtcaa cggcctgatc gtgatgtcct tgatcgacca
    26821 ggacgtgaag cgtgcagagg cggaactcgt ggagcggttt gcctcggcac tccaggtcac
    26881 cctgcctgag gtgacgaatc tccgccatgt tgtgaagaag gaactattcc acctccgcct
    26941 cgatttggtt cgccgttcga tgatcgcgcc gttatttcgg cagatgccga cgggaaggca
    27001 gtcggaattc ggcacgcgac agcatccggc gctgccgaga aagaagtggc gtgaattatg
    27061 gcagaagaat cggtggttca cggccatggt gtagacgggt tcggcaggaa cgcgatttgc
    27121 tgtgatcagc cagcgttgct tctgttgatc aagtgagtct gtcgccagtt tcatctgtca
    27181 atggtcggga ggaatggtca tgaatcgtcg tggatggatc ggatcgtcgt tgttgatgct
    27241 gacggtgatc ggaatcgggg tcgggttggc ggtgtggaaa tatggcagca tccaggatca
    27301 agccgctgcg tcgaccaatc agccggaacc gatggaagtc gtcacgctcg cagtggcccg
    27361 ggccgttgac catcaccaga ctgcgacctc gatcgggacc gtgttggccc tccgctccat
    27421 taccctccgc aatgaattag ccgggacggt cagccaggtg cggttcacgc cggggcagat
    27481 tgtcgaagcc ggcacggtgc tggttgccct cgatgtgtcg gtggaagaag ccgatcttcg
    27541 ggcacagcag gcccaggcgg tgttggcccg tactgtcctc gatcgacgcc gggcgctgac
    27601 acaggatctt gctgccgcgc aggaagaggt tgatcgcgcc ggggcggatc tcgatgtcgt
    27661 gcaggcccaa atcgcacgca ccaaagcgtt aattgcgcgc aagaccatcc gcgctccgtt
    27721 ccgtgcccgg gtcggcctcg ccgacgtgca ccccggacaa tatctgaatg aaggcacgca
    27781 gctcacgacg ctacaaggca tcgatgaagc cgtgcatgtg gactttgccg tgccgcagca
    27841 tgtggcggcc ggattgcgac acggcgacct ggtggatgtg tatccggcgg gtgacacgtc
    27901 tgtgcttcag gccaagatcg tggcgttgga tgcccgcatc gatcccgcga cacgcaatgc
    27961 catggtgcgc gcaagaatcg atcggtcacc ctcgatgccg acaccgggcg cggccgtgcg
    28021 gatcaaggtg cgggtcggtg cgccgcgcag cgcggtggcg attccggtga atgcggtgcg
    28081 caaggggccg ggaggcgatc aggtatttgt gatcaattct gacggtcaag gcaaatcgcg
    28141 cgcgcaggtg cgtcacgtgg agagtggtgc gatgtcgggt gatgacatca ttgtctatgc
    28201 cgggttggcc gccggagaac aggtggcggc atccggtgcg tttaaattgc gtgatggcgt
    28261 gttggtggtg gcggccggtg ggccggtcgc caagtccgac gcaactcctt cgccggagca
    28321 accgtaaatc agagaggcat gaccatgcgt tcattcactg atgtcttcat caagcacccg
    28381 gtcttggccg tggtgatcaa tctggtcatc gtcctcgtcg gttggcgcgc gctgacgacg
    28441 cttccggtgc agcaatatcc taagatcgaa agttcgtcgg tcatcatcac caccgtctat
    28501 tacggggcca gcgccgagac ggtgcgcggc tttctgacca cgccgattga acgggtcgtg
    28561 tcggccatca gcggcgtcga ctatctggaa tccaccagcc gggcgggcat cagcaccgtc
    28621 acggtgcacc tcaagttgaa ccacagcagc acggcggcgc tggcagaagt cacggcacgc
    28681 ctgcaacagg ttcgctctga gctgccggcg gaggcggaac caccagcggt ggaggtgcag
    28741 cgggccgatc gtccttatgc ctcgttttat ctgagcttca cgtcaccgga acgcacggtg
    28801 ccggccttga ctgattggtt gctgcgatcg ctccagccgc aatttgccac cctgaccggt
    28861 gtgcagcgcg tgacgatcga gggcggacgg cagatcgcca tgcgggtctg gatcgatccg
    28921 gaccgtctcg ccgcctacaa cttgtcgccc ggcgacgtgc aagcggcgtt gcggcgcaac
    28981 aactacctgg cggctgtcgg ccggacgaag ggcaacctgg tgcagatcaa tttgctggcg
    29041 aatacggatc tgcgcagcac cgaagagttc gaagacctca tcgtcacgga ccgcggcgga
    29101 gccatcgtgc gtttgagaga tgtggcgcga gtggagaacg gcgctgagga agctgaaatg
    29161 gtcgccaagt ataaccgcac ggaaggggtg tatctcggta tctggcccct ggtgggttcg
    29221 aacgaaatcg aggtggcgca ccggttgcgg gaggaaatgg accgcattcg ccccacgctg
    29281 ccgaaggata tcgatatgca gttggtgtgg gacggcacca tgttcatgcg gagcgcattg
    29341 gaggaaatca ccaagacact cggtgaaacg gtgctgatcg tggccacggt ggtgtttctt
    29401 ttcatgggtt cggtgcggac agcgttggtg ccgctggtcg ccatgccggt gtcgttggtc
    29461 ggcgcggcga tcttcatgta cgcattcggc ttcagcctga acctgttgac gatcctcgct
    29521 attgtgttgt cggtcggatt ggtcgtggac gatgcgatcg tcgttgtcga aaacgttgaa
    29581 cgtcatgtgc gcgaggggaa atcccgaata caggcggcgc tgctcggttc gcgtgaactg
    29641 gtcgggccca tcatcgcgat gacgatcacg ctggcggcgg tgtatgcccc gatcggcttt
    29701 caaggtggtt tgaccgggtc gctgtttttg gaattcgcga tgacgctggc cgccgccgtg
    29761 gtgttgtccg gcgtggtggc catcacactc tcgccggtga tgagctcgta ttttgttcat
    29821 cctgaaggta aggaaggtcg gttgaccaag atggtgaatc gggtcttcga cgccacgcgc
    29881 gcaggctatg gacgtctgct tgatggggcc ttggagatgc gctgggcgat tgtggtcgtg
    29941 gccctcttgg tgatggtcgc ggcctggccg ctgtatcagt tctcccggca ggagctggcg
    30001 ccggtggaag atcagagtca catcagcctg tttctggaag ccgcgccgga ttcgacggtg
    30061 gcggccacga atcgggattc tctcaaagtg atcgatgcgc tccgagcgtt tccggaggcg
    30121 cgcttcacct ggtcgctcac gtcatcgtgg ggcgggttcg gtggcttggt cgcaaaagat
    30181 tggcgcgagc gctctcgatc gacggagctg atgtatggcc aggtctatgg cgcggtgtcg
    30241 caaattcccg ggttgcgcgt ctttccgcgg ctcgatccgc ccctgccgac gccggggcag
    30301 tatgacgtgg aattgattct ggaaagtcag ttgcctgccg agcagttgat ggaaacaacg
    30361 gcggccgtgc tcggtgccgg atggcagagc ggaaaatttc tgtatgtcga tacggacctc
    30421 aagctcgatt tgccagaggc gcgcgtgctc atcgatcgtg agcggctggc cgacctgggg
    30481 ttcgacctgg cccgtgtcgg gcaggaactg ggcacgctgc tcggtggcgc ctacgtgaac
    30541 cgcttcaatt tctatgaccg gagctacaag gtcattccgc agatcggcga caaggatcga
    30601 gccacgctgg atccgctgct ggacttgaag atcaagacgc ccggggggca gctggtcccg
    30661 gtgtcgacct tcacccgcat cgagaccagc acggcccctc ggacgctgaa tcggtttcag
    30721 caacggaatg cggtccgcat cttcggcgga gtgaagccgg gcgtgacgaa ggacgaagcg
    30781 ttgcgtgtgc tggaaacggc tgccgcggcc gccgccggtt ctcgcgcgac tctcgattat
    30841 gcgggcgaat cgcgccagat ccggcatgag gggtcggccc tcatcgtgac gctgggattc
    30901 gccgtggtgc tgatctatct ggtgctggct gctcagttcc agagttttcg tgatccgttg
    30961 atcgtgctgt tgggctcggt gccgttggct atctccggcg cgctcgtctt tagtttcctg
    31021 aacctcacga cgatcaacat ctattcgcag gtcggtttga tcacgctggt gggcctcatt
    31081 gcgaagaacg ggattctgat cgtggaattc gccaacacct tgcaggcgcg tggcctgtcg
    31141 aagacggcgg cgttgcgtga ggcggccatg acgcggttgc gccccgtgtt gatgacctcg
    31201 gcggcgacgg tgttcggcca tctgccgctg gtgctggtgt cggggccggg cgcggcagcg
    31261 cggaacagca tcggcatggt gctggtcacg ggcatgacgg tcggcacgct gtttacgctg
    31321 ttcgtggtgc cggtgttcta ttcgttgatc gccacgcgcc accaaccggc cgaggagttg
    31381 gaaccggccg aggaaccggg tctgcaactc gcgggggcaa aggggtgaat ggactcatta
    31441 tgttgaaaat tacatcggag cagactggag attccgcccg gctgaccctg gagggcagtt
    31501 tgagcgggcc ctgggtgacg gaattggagc gaacctggca gaccgtgcgg ctgtccggca
    31561 tatttgcgcc cgtcgtagaa ctggtcggga tcacgttcat ctcggaagac ggcaaggccc
    31621 tcctggccag gatgtggcgg gaaggggcgg ccttggtcgc ccatggctgc tgtaccaggc
    31681 acattgtcgg tgaaattacc ggagcagccc cggtggcggg ccccggccag tgcgaccctg
    31741 catagaatag gttcatcatg cgtatgattg cgtgtgtcat cactctgctc ctcgtgaccg
    31801 gctgtgccgt cggtcctgac tattcacgtc ccgaccttca gatgccgacc gggttccgga
    31861 tggcggtttc tgatcaggaa acacagtcct ttgccaatct tccctggtgg gatctgttgc
    31921 aggacgaaga actgcgccgg ctcattcgcg tcgcgctggc ggagaacaag gatctgcagc
    31981 gcgcagtggc gtccgtggaa gaattccagt cgcgcctgct catctcgaag atggatttcg
    32041 ctccgaaggc cgatgtcacg gccaatgcgc cgtcgttcgg ccgtaaggcc aatttcctgt
    32101 ttccaggatt tcccaatccg ttcaattact atctccaagg aaatctgtcc tgggaattgg
    32161 atatctgggg acgggttcgg cggtcgaacg aagccgcgag aggagatctg ctcgcccgcg
    32221 aagaagcccg gcgtgcggtg gtgctgcagt tggtgagcgg ggtggcggag gcctactttg
    32281 aattgttgca gtttgacatg cagctgggtg tggcgcagcg caccttgaag tcgtgggagg
    32341 aatcggtccg gattgccgag gcccgattgc gtcaggggat gatttcacgt atcgacgccg
    32401 atcagttcga ggcggagcgc gcgaatgcgg ccgctcgcgc ggcggaattg accaggcaga
    32461 tggtgcagaa ggagaaccag ctcagcatcc tgcttgggcg accgccgggg caagtggcgc
    32521 ggggccgttc tttgacggag caggtgttgc cgccggaggt gccggccggt ctgccgtccg
    32581 aattgctcca gcgccggccc gacctggtgc aagccgaaca ggaattggcg gcggccacgg
    32641 cgaggatcgg ggtcgccaag gcggatcgat tcccgaagct gagtattacc gggatcctgg
    32701 gcgtggcgag cccgcaattg tcgcggctga tcgccaacga gacggcattc ggggtggtgg
    32761 gccccggcct ggcaggaccg ttgctgaacg cgcagattct gggctttcag caggacgccg
    32821 ccgaggctca gagccggaaa gtgctggccc ggtatgaaca ggcggtgctg gtcgcgtttc
    32881 gcgaagtaga ggatgcgctg gtggcggtgc gcacgtcgcg ggaacaacgg gacgcgcagg
    32941 cacagcaggt cgatgcctta cggtcggcct tgcggctggc caaccttcgc tataagggag
    33001 ggctggccaa ttatctcgat gtgctggtcg cgcaacgcaa tttgttcgag gcggagctgg
    33061 cattgaccgg tacccaccgg ctgcaactgg tctcggtggt gcagctctac aaggctctcg
    33121 gtgggggatg gtcgccgctg gatatggcgc aacagcaacc ggggcaggct ccaggaacgc
    33181 gagggcacgc tctcccggcc gccggcacct caccggccgg tcacggatga tggcgtcggc
    33241 cggctcgctc accttctgcc agagtgtcac ctctgcctga ttcagtctgg tggtcgtcgc
    33301 tttgtcatag cactgctccg tctgattctc cctctgtacg gtgaccgcgg ggcggaccgc
    33361 aggaaattcg cttccatatt tcagccggtg tatactccat cctccccttt gcctaccgaa
    33421 cttttcttag gttcgaccaa ggagtaggcg ttttctgagt ccagattgag cacagtcgac
    33481 caggggctat gcccttgatg tggaacggcg aattgcgtgg ttctgcagag acgccgtttt
    33541 ccacaaccac catccgggtg ctacatgccg ggatgtctcg atagaggggg ccatcgcgcg
    33601 ggtaatggca caggctcccc aacgagagat gacactcagg aggacgtacc cgctatgccg
    33661 atgaagcccg tcattctgtt cgtggatgcg aacagcgttc atgtgaacgc gttacgcgag
    33721 gcattgcacg gcgaagaggc cgaactattg tgtgccgcct cgtctgctga ggcagccgaa
    33781 gtgctgctga cacgtgaggt ggtgctcgtg gtgatggccg cgcggctgtt acagacggag
    33841 ggattcaaat gtgcggaaac gctgcgtgga atgaaacgta cgcgccatgt gccgctcatc
    33901 ctcatcacgg aagccggtga cgatgaacag ctgacgattc ccgcgaatga cgcgggaata
    33961 ctggattccc tgcctacgcc gatcgatccg cgtcagtggc gcagaaagtt caggatgtat
    34021 ctcgaagtca gccggcagcg gcaagaattg tctcagcaac gcatggcttt gcgcacggct
    34081 ctcgatgagc agcgagggat gcaagcgcag ttgcgggatg aggaggaacg gtaccggctg
    34141 gcattaaccg cgacgcggga tgccgtctgg gtgtggaaca ttgaaaccga cagtcaggtg
    34201 tggaatcagg ccggcgctga tttgttcggt tggagtgagg tcgtcgaaca gccacaacct
    34261 gcgcaatggt gggtagaccg ggttcatccg gacgaccgtg aacgtgtggg tggggcgttt
    34321 cacgaggcca tcggcacccc gtcggtgacg cattgggcgg atgagtatcg cttcctgaag
    34381 cgggatggaa cctatgcgtg ggtcctggat catgggtata tcgtccgcga cgtgcgcggc
    34441 tcggcgaagc gtgcggtcgg cgccatgcag gatattaccg agcgtaagcg ggcccaggaa
    34501 attgcggcgc acttcgcggc tgtggttggc tcgtcgttcg atgcgattgt cagcaagacg
    34561 ccggaaggcg tgatcacgag ctggaacgcc gcggctgaac ggatgttcgg gtactccgca
    34621 tcggaaatga tcgatcacac ggcgcaccgg ctcattccgg tcgagctcca tgccgaggag
    34681 aacgacatcc tcgcgcgcat ttcatgcggg gaatccatcc agcactacga aacggtcagg
    34741 ctgacgaaag acggccggcg ggtagacctt tctttgacga tttcccccat cagagattcc
    34801 aaggggcaga tcatcggatc ctctcagatc gcgcgggaca tcacggaaca gaaacgccag
    34861 cgtaccgcgc tcaaggaaag cgaagaactg tttcgcgccc tggtcgacca gatgtcgcag
    34921 ctggcctgga tgatggacga caccggtaac gtctactggt tcaatcagcg atggtatgac
    34981 tatacgggca tgacgatcga gacgatgcac ggtgaggcct gggaccaggc ccaccatcct
    35041 gaccatcgtg cacgcgtgct ctccagcagg cgccggtctc ttgagacagg agagccgtgg
    35101 gaggagacct gcctgctgcg cggaaaggat ggccaatatc ggtggtatct cacccgtgcc
    35161 gtcccgattc gcgacgatca aggccgcatc gtccggtggt tcggtacgaa caccgacatc
    35221 accgaacaca aacgaaccga ggaggacctg cgaacggcgg agcaggctct gcgccaaagc
    35281 gacacgcgat tccgtgaatt ggtggagcgg tcaccgttcg gcatctacgt cgtcgatgcc
    35341 gagttccgca ttgcgcatat gaacgaagcc gggcaaaagg gcgccttctg taacgtacgg
    35401 cctgtcatcg gccgcgactt cggcgaggcg atgcgcattt tgtggcccga ggctgtggcg
    35461 gctgacatta tcaaacagtt ccgtcacacg ttggagacgg gcaccccgta tcgttcgcgc
    35521 gacttcatca atccgcgcgc cgacctccag caaaccgaag gctacgaatg ggaactgcat
    35581 cggctcaccc tgcctgatgg ccggcacgga gtaatttgct actactatga ttcgacgaga
    35641 ctccggatgg tggaagtcgc cttgcgcgag agcggggagc ggttgcaagc ggctgcggcc
    35701 gacctggaga agcgggttga cgaacgaacg cgtgatctcg tgcggtcgca ggcggacctc
    35761 cgtgcgctgg cgtcagaatt gaacctgacc gagcagcgtg agcgcaagcg cctggccggc
    35821 gagctgcacg accatctgca acagatgctg gtcttcggga aattacagct ggggcgcggg
    35881 atgatgcaaa ccggggtgga tccggagtgc atggaggtga tccgcggcgt ctacggcatg
    35941 ctctccgagg cgttgaccta cacccatacg ctggtcgcag aattgtgtcc gccggtatta
    36001 cgcgagcatg gactgttagc agggttgcgg tggctggccg actatatgaa gcggtatggc
    36061 atgaaggtga cggtgaaact gccggacgag gaagatttag cgctcccgga agactgcacg
    36121 atcttgctgt ttcaatccgt tcgtgaatta ttgatgaacg cgcataagta tgccgggaca
    36181 gggctggcgg aagtggcgct cgtgcatgga cagggcgcgc tcatgattca cgtgcgggat
    36241 cgaggaaaag gatttgatag tgctgcggcc acctccgcag atctggcggt cggcggcagc
    36301 tcatcaaagt tcggactgtt cagtatcaaa gaacgcatgc ggacattggg cggaagtttt
    36361 gcgatcgcct ccgcgcccgg tcaggggacc acggcgacac tgaggctgcc gctgacatct
    36421 cgggcggcgg gggcggagcg cgtgggcgat gagaaggagg ttcccgctgg tacgccggcc
    36481 gtacaaccga acccgatggg gacgagaccc attcgcgtct tgctcgttga tgaccatgtc
    36541 atgattcgac aggggttgcg ggccgtattg gaaggatact cggacatcga gctgatcggg
    36601 gaagcgggaa acggcgagga ggctgttgcg ctagtcgatc ggcttgagcc gtcggtcgtt
    36661 gtgatggata tcaacatgcc gaagatgaat ggcatcgaag cctccggacg gattactatg
    36721 cggcaccccg ccgtcgccgt catcggactc tctgtcaatg cgagcgcgga caaccagtct
    36781 gccatgttaa aggccggcgc tcgccagctg ctgacgaagg aagcggctgc agaacagttg
    36841 tatggcgcga tcaaaagcgc cgtcggaata tccgcctgag tcttctcctt gctgcgtcgc
    36901 atggcgtctg ccgtctgtca tcgtacgctc gaccgaaaaa acctctgcat gtcgagaagg
    36961 accggcgtcc tgcgaaggtt cagccatgtc agggccgcgg ccaggtctct atgtccggct
    37021 cccgggtaga tctgtgtttc cacgcggccg cctttttcct tgatgcgctg ctccagccgt
    37081 tcgagattag cgacctttac cgcgcggtct gcatcgccgt ataacagcaa catcggcggt
    37141 tgccggccgt caatgaacgt cgtcacctgc atgttcggat agttgctcgg agggccgaac
    37201 atgtcttcca ggtccggctc atccggagta aaggcgtagg gccccgcaag cccggcaaag
    37261 tcacgaatca cccgtgaccg gtccttgccc tcattggcca gatatccggc atccgccgtg
    37321 agcaaggcgc cgatgtgggc tccggaagaa tgtcccgcaa catggatccg ctccgggttt
    37381 ccgtgatatc cggcaatgtg gtcgtacacc caggccagcg ctttcgcacc atcctcgaca
    37441 aactccggaa agcggacccg gggatatttg cgatagtcgg ggaccaccac gataaaattc
    37501 tgttctgtaa acgctgcccc gacgaatcga taattgtgct tctctccctc cgtccatcgt
    37561 ccgccataga aaaatacgat cacatccaac ggttgatgcc cggcgccggc aggaacatag
    37621 atgtctaatg tgcacgcagg ctctggggag taggccacgt cctgcaccac cgtcatctca
    37681 tgaaagcgag tgggaagatt gacggccgtg aaggtggctt gcgagcagcc ggatgcggcc
    37741 agagacaagc tcagcatcat tatgggaaac aggagattct tcatgccgtg ccttgcgacc
    37801 tcatacgccc caggggcggg cggagaagac cccgcctgcg cctcggccta aggggccatg
    37861 tgactggcgg tccggtactc ataccacaac gaagatgtcc aagttcatgt ccacgcaact
    37921 tccgggagcg tatggccttg acataccgca ccctccgtgg caggaacgat gcctcgcaca
    37981 gcgccaacca tcgttgcacg ggtcgtgcat ccgctgtagt gtgagatgta tgaacctgtc
    38041 ctaatgagga ggctcccatg ggacgccagg cgagggctct atgacgaaac tcctgcgtat
    38101 cacgaccaaa cagttgaagg agatagtgga tgtgaccgag ttgctccagg caaccattcg
    38161 taacgccaac atgaaggaag ggctgtgctc ggtcttcgtg acccacacga ccgcggctgt
    38221 gacgacgggc gaaatcgggg aggggaccga acaggatttt ctccagatcg tcgaagaagt
    38281 catcccgcgc attcagttcc ggcatgctca cgatccgtcc catgcctggt cgcacatggc
    38341 tgcgtcgatg ttgggtccct ccttgaccat cccggtatca ggggggacac tcgtactcgg
    38401 cacgtggcaa tcggtgatgt tggtggaact tgatggcccg cgtgatcgga acgtgcacgt
    38461 ctccctgatg tcattctgac agacgtctga aagatgcgag gcggccgctc atgagccgcg
    38521 ctggttcaga gggaggcgag atggcagaga tcccggccgg cggtgtgatc gccgattttc
    38581 ttgcggagga ccaccggcgg ctcgatgcct tgctgcaggc gaccgatgcg caccccggcc
    38641 ggatcgaccg cgaggcctac gatcagttcc gtgcgggcct gctgaggcat atcggcatgg
    38701 aggaaaaact gttgttgcct gcattgcaac gatggcgagg cggggagccc ttaccggtgg
    38761 ctgcgaggct gcggctcgac catggcgcgc tggccacgtt gctcatgccc accccgaccg
    38821 ctcagatcct ggcgacgatt cgacggatct tgtcggagca taatcgaatc gaagaaggtc
    38881 ctgatggatt gtatgccctc tgtggtcagt tgccggatac agaagcgaca cgactgtggg
    38941 acgcattgcg cgctgcgccg acggtgagcg tcatgcggca ttcggacagt ccggcggtca
    39001 tgaaaacctt ggagggcgca cttgccaggg ccggatatcg tctcgaggcg ctcgctccgc
    39061 gtgaggaggg agaatctcga tgaccgtgcc gaagggaccg tcacgatgat gatccgtcat
    39121 ccgcgacggc ttccactgct tgcgctcggc atgttggcct tactgacggg gctctgggcc
    39181 ggcgtcgcgc gactcgggtg ggatgtgcct ctgccgcgat ccgggttttc ctcattgcat
    39241 ggtccgttga tggtgtccgg ctttcttgga acgctcatca gtctggagcg agccgtggcg
    39301 ctcggccgat cctgggctta tgcagcgccg ttgctcaccg gtcttggcgc cctggtcttg
    39361 atcgcaggcg gtccgctggt ggttgcccag ctcttgctgt tgagtggcag tgcggggctg
    39421 gcggcgattt ttgcagccat catccggcgg catccggcct tgtacacctt cacgatggga
    39481 ggcggggcaa tcgtctgggc tgtcggtaat ctgttgtggg ttctcggttg gcccgtcttt
    39541 ctggtcgtct tctggtgggc cgccttcctc gtggtgacca ttgcgggtga gcgtctggaa
    39601 ttggcccgtt tgcagcaggt gacgcgcggc gcgcagacgg cgttcttgct gttcctcggg
    39661 gtgttaggtg cagggctgtt gcttctggga tggtggttcg acggcgcggt gcgtctcttc
    39721 ggtgccgggt tggccgctct ggccctatgg ttgggcctca atgacattgc cagacgaacg
    39781 gtccaccaaa cagggctgac acgcttcatc gccatctgcc tgctcagtgg ctatgcgtgg
    39841 cttggcgtga gcggcctggc ggcgatggtc tatggcggtg ttcccgtggg gccgcagtac
    39901 gatgccatgc tgcacgcatt ctttctgggg ttcgtgtttg cgatgatctt cgcccacgcg
    39961 ccaatcatct ttccggcggt gctcggtgcg cggatgacgt atcgaccggt gttttacgcg
    40021 catgtgttgt tgttgcaagc gacactgatg gtgcgactgg ttggtgacgc agcggggtgg
    40081 ggggcgggac ggcagatcgg cgggctcctg aatgcggtga cgttggtgct gttccttgcg
    40141 aataccgtta cggcccttgg cagtttgccg gatcggccgg tcgtcacgag tcgcgccggg
    40201 tcctgatgtt gatcatagtg aagacgtcct cgtagcacgc acaagggagt gttggatgac
    40261 cagagagaaa cagggggcgc agtcagatcc ccgggtgatg gaggccttgc gtcaggtggt
    40321 ggatcctgag ttggggatca acatcgtcga tttgggattg gtctatggca gcgaagtgcg
    40381 cgaaggccag gtccatgtca cgatgacgat gacgacgccg gcttgcccga tggaagagct
    40441 gctgatggag atggtgcatt cggcaatctt gcgcgagctg tccgaggcac gttccgtgga
    40501 ggttgatctg gtatgggatc cgccgtggaa gccggacatg atgagtccgg cggcgaaagc
    40561 ccaactcggc cggacgtgag ggtgagccca tgagtgcggg aggcggcaag gtctacccgc
    40621 tcgagaagga ttgtgaccgt gaccgaaaac cagtctcagc aggtgcgcgc actggtggat
    40681 gaggtctacc gcacccagtc ccgccaggtc ctcgccacct tgattcgctt gctcggagat
    40741 ttcgatgcgg ccgaagaggc gttgcatgaa gcctttgccg tcgcagtgga acaatgggcg
    40801 cgtgaagggg tgccggccaa tcctcgcgcc tggctcgtct cgacggggcg cttcaaggcg
    40861 atcgacggca tgcggcggcg ggccagattc gatgcgtcgc tgcctgacct tgcccaccat
    40921 ctggaactca ccgctgaccc tgtcatagat gagggggagg attcggttga ggatgaccgg
    40981 ttacgattaa tctttacctg ctgccatccc gccctgtcgc cggaagccca ggtctccatg
    41041 acgctccggg aggtctgtgg tctcacgacc gatgagattg cccgcgcgtt cctgacgaag
    41101 cccaccacga ttgcgcaacg cattgtgcgc gccaaaggca agatccgcga cgcccgtatc
    41161 ccctatgagg tgccgtcgga gactgatttt ccggaccggt tggatgcggt gctgagagtc
    41221 gtctacctcg tgttcaacga gggctacagt gcgtcgtccg gggattcgct gaccaggcat
    41281 gatttatccg gtgaagcgat acgccttggg cgggtgctgg tcgggctgct tccggaagcc
    41341 gaggtgttgg gactcctggc ggtgatgctt ctgcaagact cccgtcgcgc cgcacggacg
    41401 tcgccgaccg gagatttgat tctcctcgaa caacaggacc gctcgctgtg gaatcgagac
    41461 cagatcgccg aaggcatggc cctggtcgaa ctggcgctgg cgacccgccg ggtcggtccc
    41521 tatacgattc aggcggccat cgccgccgtg catgcggaag cgccggaggc tgcgctgacc
    41581 gactgggcgc agatcgtagg cctgtatgac gtgttgttgc aggccgaggc gtcaccggta
    41641 gtggaactga accgggcggt ggctgtggcg atgcgtgacg gtccgtcggc gggtcttgcg
    41701 ctggtcgatg ccattctctc gcgtggcgat cttaccaatt atcatctggc gcattccgcg
    41761 cgggcggacc tctgccggcg acttggacga aacacggacg ccgcagcttc atatgaacgg
    41821 gcgctggcac tcacgcagca ggaaccggag cggcggtttc tggaggggcg attgcgggaa
    41881 cttggttgag gcgactggtg tcgaccgccc tctgtgttct ttaagtggtt gatatcgcga
    41941 cagcttcatg gctgcgtcga aggatgtcga ttttccccgc cctcgacgac tatctcatga
    42001 caggagccat tcataaggga ggatgccatg gcgaagcgta ccccgacgcg caagacgacg
    42061 aagaaagctg attgtccggc cagtttggtg tggttcgata ttcctgccga cgacctggcg
    42121 cgagccaaga agttctacag tgcactgttc gggtggaaga tcagccggtt ccccgcgatg
    42181 ccggactatt ggcatattga taccggcggc gagaaggcga cgctggatgg cgggctgctc
    42241 ccgcgccagg cgccgcgtca gccgattacc gcctatgtgt ccgttccgtc cgttgagaag
    42301 gccgctgcca aagtgcagaa actcgggggg acggtctgca aatccaaaac gcctgtgccg
    42361 ggcatgggct attttgtgat ctgtcaggac acggagagca acacatttgc cttgtgggag
    42421 atgaatcctc aggcgaccta gactgagggg cacgcggcat gatccgcgaa cgttgaatca
    42481 tacgaggaat agatcatgaa atatctctgt ctggtgtatg tcgaagaaaa gatcctgcat
    42541 gcgctgccga gtgctcagcg ccagaccctt tcggacgaat ccatgtccta ttgcgaccgg
    42601 ttacagaagc ttggtcagct ggtgacggcg tccccgctcc atccggtcga aacggctacc
    42661 acggtgaggg ttcgcgatgg caagacgtcg acgatcgacg gaccgtttgc cgagaccaaa
    42721 gaacaactcg gcggcttcct cctgctcgat gtgccggatc tgaacgatgc gatccgtatt
    42781 gcctcgcagt ttcctgccgc tcgcatcggg agtgtggagg ttcgtcccat gaaggaacag
    42841 ggttgcgctt gaccggtatc gatagggtgt gatccccgtc atgcagtcag gacatcacct
    42901 cgcgccgcag gccggtgcga atcgaggaag gagcagcata tgagcagggt gcgagtgctt
    42961 gtgggaacga ggaaaggggc gttcattctg acatcggatg gcacccggaa gcagtgggac
    43021 gtgacaggtc cgcatttcgg cgggtgggaa ctgtatcacc tcaagggatc atccgctgat
    43081 cctaaccgcc tgtatgcgtc gcaaaccagc agttggttcg ggcaggtcat tcagcggtcg
    43141 gatgacggcg gtaagacctg gaatcctccc ggcacgaagc ctgaggatct catgggcgca
    43201 gacggtatgc cgaatggcgc gagcaacatg tttgtctatg atcagtcggc ggaaaccggg
    43261 aagccgctca ccacgcatca acactacgac ggcacgcaac gtccttggga gttcaagcga
    43321 gtctggcacc tggaaccgtc cctgactgat ccggatacgg tgtatgccgg ggtcgaggat
    43381 gcggcgctct ttcgttcgac ggatggcgga cggacctggc aggagcttgc cggtctgcgt
    43441 gatgccaagg gcaagctgtg gcagccgggc gccggcggga tgtgtttgca tacgatcgtg
    43501 caggacccgg cgaacccgca acggatgcac attgccatca gcgccgccgg cgtgttccgg
    43561 accgacgatg gcggcaagag ctggcggccg accaatcgcg gactcaagtc gcagtttgaa
    43621 ttgccggatc ccgatgcgga ggttggccac tgtgtgcatt gcatcaccat gcatccctca
    43681 cgtccgaatg tcttgttcat gcagaaacat tgggatgtga tgcgcagcga cgatggcgga
    43741 gagtcctggc acgaaatcag cgggaacctg cccacggact tcggctttcc gatcgcggtg
    43801 cacgcgcatg aaccaaatac cgtgtacgta gtgccgatca agagcgactc cgagcattac
    43861 cctccagagg gcaagctgcg ggtctatcgc agccgcagcg gcggcaatga atgggagcct
    43921 ctcacgaagg ggctgccgca gcagaattgt tacgtgaaca tcctgcgtga tgcgatgtct
    43981 gtcgattctc tcgatccctg cggcctctac ttcgggacga ccgggggcca ggtgtacgcc
    44041 tcggcggacg gcggggatag ctgggcgccg attgtgcggg atttgccggc ggtgttgtcc
    44101 gtcgaagccc aaaccctata acgaagcgct gaaaccgccc tcccgcggcg ttctcgcctc
    44161 ggacgcgtcc tcaacgtagc ccagggctac gcctccggcg cctccgtcgg ctgcggcctt
    44221 gctggcggag cgttttgagc gctcgttggg ctggccggct ttttaaggag cctgttcgga
    44281 caccagatgt acgtacgttc tgtctggagg tgcttcatgg tgcgcgtcat attgcctcaa
    44341 catttgcgga cgctggcaaa ggtcgaaggt gaagtatctc tggaggtagt gggggccgtg
    44401 acccaggaga cggtactcga tgcgctggag gtgcgttatc ccgtgttgcg tggaacgatt
    44461 cgagaccatg tgaccaaacg gcgtcggccg ttcatccggt tctttgcctg cgagcaggat
    44521 gtgtcacacg actcgccgga tgtgcctttg cccgaatcgg tcgcgaaggg cgcggaaccg
    44581 ttgttgatcg tgggggccat ggccggcggc taatcccgct ttgtagagag atgcgtggag
    44641 gcaggtccat gaaatatctg ttgctggtgc atcatagtga agaagcgttc gccaagatgg
    44701 ctgaaaccac gaggcgggag atgttggccg aatcggtgca gttgacgcat caactccacg
    44761 ccaaggggca atatgtcagc gcctcgccat tgcatccgac ttccacggcg gcgcgtgttc
    44821 aggttcggga gggacgggcg atcgtgaccg acggtccgtt tgcggaaaca cgtgaacaga
    44881 cggccgggta ttttcttgtt gaggccagtg gtcttcagga cgccattgat attgcagcgc
    44941 gcattcccgg tgcgcgtctc ggtaccgtgg aggtgcggca ggtccgcgag atcgacggtt
    45001 tgccggaatg atttgccgga atgagatgtg gcgcgagaca cccaacgacg gttcgaagct
    45061 ggggtgatcc cgactacaca gatgtaaccg acatgggcaa ggtcaatcgc gtgaagaggc
    45121 cgatgatggc ggaatgcttt cttcaattct cgggctacac gcgaagctcg acggactgtt
    45181 ccctcaaacc atgggaacgg ttcaatcgaa aggagcaacg atgagcacgt cacacgccaa
    45241 gccgatacca gacggaatgc atacgattac ccctcacctg atatgcgccg gtgctgccga
    45301 cgctattgag ttctataaga aggctttcca tgcggtggag ttggggcggg tgcccggagc
    45361 ggatggaaag cttctccacg cgctgattcg catcggggat tctcccgtca tgctggtcga
    45421 tgaatttccc gatcatcaca cgctcgggcc gaaatcgatc aaggggtcgc cggtcaccat
    45481 tcatctgtat gtcaaagatg tggatacggt cttcaaccgc gccgtttcgg caggcgcaaa
    45541 aagcacgatg ccggtcagcg atatgttttg gggcgatcgg tatcgccagc tgggggatcc
    45601 tttcggccac cggtggtcgg tcgcgaccca tgttcgtgac gtcgacccac aagcattgca
    45661 ggaagcggca cggaaggcct gtgagtaaga atctttttcg gcgtgcaata catccacatg
    45721 gagatctgac atgcgctacg tcgatggttt tgtgctggcg gtcccgaaga agaatgtgaa
    45781 tgcgtatttt aagatggcca agaaggcctg caaagtctgg acggagcatg gtgcattgga
    45841 ataccgcgaa tgtgtgggcg acgatctcgc ggtcaagatg ggcctgccgt ttccgcgact
    45901 ggccaaactc aagcaagggg aaaccgtggt tttttcatgg atcgtctaca agtcgcgaag
    45961 tcatcgcgac cgtgtcaacg ccaaggtgat gaaggatccg cggattaatg aaatgtgtga
    46021 tgaaaaggcc atgcccttcg atgtcaagcg catggcctat ggcggattca aggtgatggt
    46081 ggatggagga acacggtcat gaggccgttg cctcattgat cacttgatca catgctcacg
    46141 gtttcttggc tgcatggaca acgataaatg acttggagat ctgttgccgg aaagggtgag
    46201 ccggcccatg tcgattcagg caagcgccga cgactacttt gtgaaggcgg cacacatcgt
    46261 cgatctctgc tcacactgac ctgatggagg attccatgcg atttatgatc atcatcaagg
    46321 cgaccaaaga ttcggaagcc ggcgtcatgc cgagccagca attgctgagc gagatgggga
    46381 cgttcaacga ggaactcgtc caagccggcg tgatgctggc aggggacgga ctccatccaa
    46441 gtaccaaagg ggcgcgcgtc cgattctcag gcacccgacg caccgtcatc gacggcccct
    46501 ttgcagagac gaaggaactg atcgcgggct attggttatg gcaatgtggc tccaaagagg
    46561 aggcgatcga gtgggtcaaa cgttgtccca atccgatgcc tggcgaatcc gagattgaaa
    46621 ttcgccaggt tttcgaggcg gaggacttcg gggccgagtt caccccggaa ctgcgagagc
    46681 aagaagatcg cctgcgcgcg cagatggcac agaaccaata ggcaaggtct gatttcatct
    46741 ggggtgcatt gaccagccca ttgccacgtg attgactaga gtcagagacg ctgtgccatc
    46801 cagagatgtt gcacagtacc gtgtagaaac ctgacgaatc ggatggcgcc acgggatcga
    46861 cggcgccatc ttacctataa ggaggccatc atgcgcgtga catccattct gcttgcctgt
    46921 ctctgcacgt ccctcatgac catgcccgtc tctgctaagg agaaaaagtc ggagaaagcc
    46981 atggatcctc aagccatgat ggaagtgtgg aagaaggcgg ccatgccggg agagcctcat
    47041 aagctgtttg ccagtctcgc cgggagttgg acgactcaga ccaaagaatg gatggagccg
    47101 gggaagccgc cgtccgaaac caccggcacc gcggaaatga agatgttgtt ggacggacga
    47161 tttctctacc aggaattcaa cggcactatg atggggcaac ccttcgccgg gatcggcatc
    47221 gacgcgtatg acaatatgac caagaaatac gtcacggcct ggatggatag catgggaacc
    47281 ggcattttta ccatgcaagg cacgtccagt ccggacggga aaacgatcac gctgaagggc
    47341 tcgcatccgg aaccgggcgg cgggcagatg catcaccgtg cggtgtggaa aatcattgat
    47401 cagaattcac agacgtttga aatgtacggc actcatgggc atgggaagga aatgaagttc
    47461 atggagatca cctatacgag aaagtcatag cactcgcgcc tctcgcagcg gacgcggatc
    47521 accgcatcgg cccatcatca aatgactgcc ggggatgctc attcctagtg tcttgggatg
    47581 gggatccccg caaccgatgg gatggtagaa gttctgttcc ggctgtcgct gccatctctt
    47641 tgtgttgtca ccgcaacatg tggcgctgtg ggctgattat gcggcgatcg tatttctcat
    47701 agtcccccca tcgtcaccat ccccctgccg aaatgtttta ttgatgtagc gccgagccga
    47761 ccgtgatccg tcgtgtgtgc aggaacaggc tcgttgctta catgccagcc aaccagtaag
    47821 atgggtacgc aatcatctcc gcccgcgcgg caattcagat tgtagtcagg agtacgcatg
    47881 atcaggcgat ggcgatggtc cactatagcc ccgatggtgt gcgggtggct cgcgttggcg
    47941 cttgtgccgg gttgcaagca ggaagccggc tcggcgccgg caccgaccgt tcctgaggtg
    48001 ggaattgtgg tggcgaccgc ccaggatgtg cctgacgaac cggagttcat cggacaggcg
    48061 gaatcgtcac gccccgtgga gatccggtcg caggtcaccg gcatcttgaa acagtggtac
    48121 ttcaaggaag gccgcgacgt caaaaaaggg gatcgtctgt atcaaatcga tcccgtgccc
    48181 ttccatgcgg cgatgctgag tgccaaggct aaagtcgccc aatcggaagc ccggttggtc
    48241 caggcgaatc agaatctgac acgcgtgaag ccgctcctgg cagaacaggc ggtgagcacg
    48301 aaagatgtgg acgatgccgt cgccgaacag ttggccgcga aagccgccct cgaaggcgcg
    48361 aaggccgaac tcgtcaaagc aaaattcgat ctcgataaca cgctgatcat cgcgcccatc
    48421 gacggaatga tcgaacgaac gcgtgtgtat gaaggccgat tggtgtcggc acaaacagac
    48481 ttgctgacca tgattcatca agtcgatccc atgtacgtga tcgtcagtgc gccggagagt
    48541 tttctgttga agcgccggcg ggacacggat gccaaacgta ttcagcatcc gggggtgtac
    48601 caactgcgtg gcgtgctcac ctttgtcgat gggacgacgt acgggcacga aggcgtactg
    48661 gatttgctgg atgtgggatt aaaaactgat acgggatcga gacaggcgcg cgtcgtattt
    48721 cccaacccgg accgggtgtt gttgccagga cagttcgtgc gagtgcggtt caagggcacg
    48781 ctcaagaccg gcgccatcct ggtgccgcaa cgcgccgttc agcagggcgc caagggctcc
    48841 atcgtatttg tggtgggcaa ggacgataag gtggagatgc gtgaaatcct ggcgagcagc
    48901 tggcaaggca gtcagtggat cgtcgaagaa ggcttgcacg tcggcgatcg catcatcgtg
    48961 gagggcctgc ataaaatcgc tcccggtgcg gtggtgaaac cggtgcccgt tcccgctgcc
    49021 ggcgcggcaa ccgctccgag tgccgccccc gccccgccgg agcccgcctc gtgatctcac
    49081 atttctttat cgaccgcccg atctttgcgt cggtgttgtc gatcgttatc atggtgctgg
    49141 gcttggtggc actgcaggcc ctccccattg cccaattccc cgaaatcacc cctcctgtcg
    49201 tgcagatcga agccgactat ccgggcgcca atgccgaaat cctggccgac tcggtggcgc
    49261 ggcccattga ggtgcaactt cccggcatcg acaatctgct gtactacgat tccaccagta
    49321 cgaacgacgg ccacatgtcg atcaagttga ccttcgagat cggcacggat gtcgatatcg
    49381 cgcaggtaca aacccagaac cgggtgaaac tcgcggagcc gcaattaccg cccgaagtgg
    49441 tccggcaggg gatcagcatc aacaaggtgt cgccggatct gttggccgtc gtggccttga
    49501 gttcgactga tcctacgcat gacacggtct atctttccaa ctatgccatt ctgcgggtcc
    49561 tcgacaacct gaagcgcctt cgtggcgtag gcaatgcggt ggtgttcggg tcgcagaatt
    49621 actcgatgcg gctgattctg gaccccatcc gcatggccca actcagcctc acgccgacgg
    49681 atgttgcgaa tgtcgtgcgg gaacaaaatc gtgattttcc tgccggaacc attggccgtg
    49741 agccggcctt gaagggtacc gagctgacga ttcctgtcat tacgcaaggt cgtctcacgg
    49801 aagtgaagga cttcgaggac atgatcgtgc gggccatgcc gaatggttcc atggtccggt
    49861 tgaaggatgt ggctcgtgtt gaattgggcg cccaatcgta caccctggaa gggcgctgga
    49921 acggcaagcc caatgtgttt ctgctgacgt tcctctcccc gggggcgaac gcgctcgaaa
    49981 cggtgaaacg ggttcgcgcc gaattgaccg aggtctccaa ggcatttccc accggcgtgt
    50041 cgtacgacat cccctatgac accacgcgat ttatcgacgt ctccattaaa gaggtcgtga
    50101 agacgctggc agaagcgatg gtgctcgtca ttctggtggt ctatctcttt ttgcaaagct
    50161 ggcgcgcgac attgattccc ggtgtcgccg tgccggtgtc cctcatcggc acatttgccg
    50221 gaatgcaggc gctagggttc tcgatcaata ccctcacgct gttcggcatg gtcctggcca
    50281 tcggcatcgt ggtggatgat gcgatcgtgg tcgtggaaaa ttgcgaacgg cacatgaccc
    50341 aggggaaact gtcggctaag aacgcggcga agcgggcgat ggaagaggtg acggggccgg
    50401 tgatcgccat cgtgcttgtg ttgtgtgcgg tgttcgtgcc cgtcggcttt cttggtggca
    50461 ttaccgggga gttgtacaag cagttcgcca tcacgatttc cattgcggta atcatctccg
    50521 gttttgtggc gttgacgctc agccctgcgc tctgcgccct cgtgctcaag ccgggcgaag
    50581 agcggcacca tgggttgttc ggcctgttca atcggacatt ttcatggatg cagggacgat
    50641 atatctcgac ggtgggaatg gcactgacgc gacgcctgct gtcggtcgcg gtgttcgcgg
    50701 tactgcttac gggcgtggtt ttgttgttta aaaccatccc caacagtttc ctgccggagg
    50761 aggaccaggg atatttcatc acaatcgtgc aacttccgga tggggcgtcg aagcagcgca
    50821 cggatacggt attgagcaag atcgagaatt attttctggc caatccggcg atccattcga
    50881 ccgatgcgct gtccgggcag aacttcgtgt ttagtacacg cggacccaat gccgcgacga
    50941 tgttcgtgcc gctcaaacat tgggatgagc gtacggcccc gcagcaacat gtgaaagcct
    51001 tgatcggggc ggcttacggg gaatttgcaa agattccaga agcgttgatc cttgccttca
    51061 acgccccgtc gattcgcggg cttggtgcga cgggcggatt ttccatacag cttcaagatc
    51121 cgagcggcgg tgacttcaat aagttctccg cggtggcgca ggagtttgtg gccaaggcgc
    51181 ggcagaatcc ggcgatcggg gccatcggaa ccagtttccg cgtcagtgct ccgaggatct
    51241 tcgccaaggt gaatcgggag cgcgccaagg cattgggggt ccctatttcg gaggtcttcg
    51301 atacgctgca agcctatttc gggaatctgt acatcaacga ctttgtgaag ttcggtcgtg
    51361 tcttccgggt gcagacagaa gccgaggcgc agtatcggtc aactcctgac gacatctcaa
    51421 aaatttatgt gcgggccgtc ggcgcgcagg ggcctacgat gattcccttg gatacggtgg
    51481 tgagcacgga gttcagcagc ggccctgatc ccgtgacaca tttcaacgga tacaatacgg
    51541 cgctggtgct tggttcggcg gcacccgggg tcagttccgg acaggtctta gacgcgctgg
    51601 ataagttagg gaaagaagtg ctggtgccga agggatacgg gatcgattgg agcggcattt
    51661 cctatcagga acggatggtc ggcaatcagt cgctctacgc attcggcttc ggattgttga
    51721 tggtgttcct ggtcctggct gcgcaatatg aaagctgggt ggtgcccttt gcggtgatcc
    51781 tcgcggttcc gatcgggctg ttcggcgcct tgagtgccgt gtggctcaag gggatgacca
    51841 atgacatcta cttccagatc ggtctggtga cgctcatcgg gctgtcggcg aagaatgcca
    51901 ttctgatcgt ggaatttgcg aacaagcgct atgaggaagg gcatcccttg ttggagggga
    51961 cgatcgatgc ggccaagctc cgcttccgtc ccatcgtgat gacgtcaatg gcgtttattc
    52021 ttggcgttgt tcctctggtg gttgccacgg gtgccggcgc tgccagcaga aattccattg
    52081 gcacgggagt gttcggcggg atgctggcag ccacatttct ggcaattttc ttcgtgccgc
    52141 tgttttttgt tttgatccgc tcgttgagtc gcggacggaa ccgtcagctt cctcctcccg
    52201 gggccgatgg acctgatcaa cctgaaaagg agcgtgatta tcagcatgcg tagcctggca
    52261 ttggtgcttt tctccactct tttagcagcc tgtgcggttg gtccggattt caaccgtccc
    52321 gaggcaacga cgcccgatgc attccgcatg gccgaaccgg gcggtgacgc tgcatcgatt
    52381 gccaatacac cctggtggga actgctgaag gaccaggaac tgcaaaagct tatccgaacg
    52441 gcgttggaag agaacaaaga cctcaaacgc gccgcggcgg ccatcgaaga atttcaagcg
    52501 cgcctgttta tcgcgaagac cgactatgct ccgcaaatga atgtgaccgc aaacgcgcca
    52561 ctcttcggtc gtaagagcaa ttttctcttc cccggatttc cgaacccgtt caactactac
    52621 ttacaaggaa atctatcgtg ggaaatcgac atttggggaa ggatccgacg gtccaatgag
    52681 gcggcgcgcg gcgatctctt gtcgcgggag gaaaatcgac gtgccattgt gttgcaactg
    52741 gtcagtggcg tggcggaggc ctacttcgac ctgctgcagt ttgatatgca gctcgacatt
    52801 gcccggcgca cactgaagtc ctgggaggaa tcggtgagaa ttgcccaggc tcgcttgcgg
    52861 caaggcatga tctccaaact cgatgccgat cagttcgaag ccgaacgggc caacgcagca
    52921 gcgaaggccg cggagttcga gcggcagaag gtccagaagg agaatcagct cagtgtattg
    52981 ctcgggcgta atcccggacg tatcgcgcgc ggctactctc ttactgagca ggtcatgccg
    53041 ccggacgtgc cgcccgggct tccttccgaa ttgctccaac gacgtccgga tattttgcag
    53101 gctgaacaag acctggctgc ggcaacggca cgaatcggca tggccaaggc cgatcggttt
    53161 ccaaaattga gtattaccgg aattcttggt gtggcaagtc cgcatctgtc ccggttagtc
    53221 gcaaacgaga cggccttcgg ggttgccggg ccagggttgg ccggtccgtt attgaatgcc
    53281 cagatcctag gatttcagca gagagctgcc gaggcacagg caagacaggc ggtagcccaa
    53341 tacgaacaat ccgtcctcgt ggccttcaag gaagtcgaag attctttggt ggcggtgcgg
    53401 acggtgcgtg aacagcgcgc cgcgcagttg cagcaggttg aggccctacg atcagcactg
    53461 agcctggcta accttcgtta taaaggcggg ttggcgaatt atctggatgt cttaattgct
    53521 caacgcaatc tttttgaggc cgagttggca ctgatgggaa cacatcggtt acatctggtg
    53581 tccattgtgc aactgtacaa agcgctgggt ggcggatgga cacctgaagg gcaactgcct
    53641 gtttcaccga tcgcgtcgcc gcctgaaaaa agttaggcgg ccaatccttc gatctgccag
    53701 agttctattc aattatccca cgtctgtggt ggtctatcga gagccggtct gatgtgccgg
    53761 cccttccttg cgcccgggat ccgtcctatg aggagatgag gacgtaagcg tgagaatcat
    53821 ggccagcgtg ccacccagtg cggccatgag gatcagggtg aggccactgt gaatccacga
    53881 tgtactcgtt tgtatgccga gggcaatgtt tggcaagttg aaaatccaga ctatcaccgc
    53941 cacccatgcc agatgttccg ttcgatcgcg aactatgcgt atgcctgcga ctgtgaagcc
    54001 aagtgcaccc gctaacaggt tcgccatata ggcagttgac ggattgctct gcagattcac
    54061 tccaaggaga gccgtgccca acgcggctgc aaatgtgcaa ccgtatacga tcgctgcgtc
    54121 gcgaaagaca gccttaagac tcatcatcat tgcgcgtgat cctgttgaac ccgctcgtcg
    54181 ggccgacctg tttccagttg tttcaagatg aagaagagga gggtctgagg aatgcctgag
    54241 gcagagtgcg ttcgtgcgct ttcccgtgca attttgtcag atgaacaaga cgtcatgtgt
    54301 gcctccttct tggcttgggc agagagggaa tctatcgtaa tgcttgcggg gtaaggaggt
    54361 tgaaatgtct gggcgatggc gtcggtccct cgcatctgcg aaggaccgtg cgggttgctt
    54421 ccggggtcca tcaaaattgt ttcttctgtg tcgaggtgaa ggtcgaaggg gtgcggggga
    54481 ctgattttcg attacgcatc catcgactga agcgcttgga taaggcatac accaggttgt
    54541 cgatggcaag caccaccgcg ccgatcatga acaatcccaa tacgagggcc agctctacat
    54601 caatggacat gctaggttat tcctggtgtc aggtcgtcag tgattgttta cgcggccaat
    54661 tcagctacgc ttgttgtgcc tgaaggttcg atttctcgct tccctgacgc cgcaaggcag
    54721 gtattcttcg cttcctgtga ctgccggttg cgctgcaaca cactttccga cacatttcca
    54781 cagttcatgc agcgccatgc gcggagccac attggtcctg aggaatcttc catatcgagg
    54841 agaaaatctt cgaccatgca accgttacaa cgaaaacagc tcattgtggg ttcctccatt
    54901 gttcagtgcc tacgtgtaag cctagaacct ggatgatttc ttcgatagac ctgaatggag
    54961 taaccccttg gtgggtatcg gtttttaatg ggagatttgc atgcaagtcg ttgtaattgc
    55021 agcgatgttg catttagtcc gccgccctaa ttgtgagttc tgtgtgcgaa tcctggaatt
    55081 ccagttctag gggaagcttt gcttcaagga agcggttgag gcgaaggcgt tcatcgacgt
    55141 ccataacaag aagttccaca ccaaatcgtt ctccttgtat ccagctgact tttgccagat
    55201 ggacggagac cggtcgtcgc tcgtcacgga gttgaatctt cacggagaga tgatccccgt
    55261 cgatgagatt gtggaaggtt gtgcgtagag ttccgcgctg ccccacatca aatacctttc
    55321 cctcctctgc acagcccatg gctacatccg acaaaatgca gtgaacgaga agctttgttt
    55381 gcgatgaacg tttcatcctt gccctcccgc gtatgcgcgt gatgccacat accgctcgat
    55441 ggcgagaata tctcgtgaaa gtctgatcag atagtctgca aacagggtac tgcgatggag
    55501 gggggcagat ggctaggtgc caacggaagg atgaagcgac gttgcagagg cgctgtttaa
    55561 actttggagg cgtcccgact aattgtagag ggatgagcgt taagggcgac agctcaccag
    55621 tcagcggaat gtaagaaggt tgttcagccc ctcatttttc ggtctgtagg caggagagtg
    55681 caggagccga gtgtgaactg attcatctaa gacttctgtg cccgtgcccg tttgcatcac
    55741 aggccgatag aatcgcgggt ggatccacct tcgaaatccg acaaaacatt cactgaacga
    55801 gtcgtgaatg gggcctaaca tattaagttt ttcgtctatt ctgcctgact ccagagctaa
    55861 tcccttggcc atggaatgtt gccgtatcca ggctaaaggc acgtcagcca aatctcgatc
    55921 aggatacgtt ccgccaaggt ctccatgtgc tccggcaaac caccgctgtt caatcacctg
    55981 cgcggctttg ggcggggaag tccagagtgt tgcgttgtga tctgctcgat gttcatcgat
    56041 agcgagggca tgacaggcgt gccgcacaat cggactcaat tcagtatcgc gaaagttgta
    56101 ccggtgttca ttcagccatc tgagcgcttt cgtgggaata ccgagcggtc cgacggtatc
    56161 ccaaagaccg agcaatgtga cgttgatgtc cgaagacccc ttccgccgac cagtcgcaat
    56221 ctgggaggcg ttctgcaggt ttcgatacac acgataggcc tcgtcgatga cgtggttgtc
    56281 aggatcggtg accattcgag tgaggcattc gcgaagatgg gcggcgacac cacctgaggg
    56341 tgagtgagga cttgccgctt cccgaacaag tctgacgtgg tctgcattga gcagcaccgg
    56401 agctgggaga ccggtgagcg tgagtaatcc taccagagag cgagcggtat aggcgcctcg
    56461 actgaagcca tacaggtaca actcgtcgcc gggatcatag gtggccgcca gataggcata
    56521 gctctgaaga atggttcgat ccagtccaca cccgaacgaa ccgtcgcgga agcggtggaa
    56581 ccaaggcatt gtcgtccccg gttcgtacca tttctgctgg atccgcccat cgcctgaacg
    56641 aggcagaatt gattgataga gttggtagac gtttgtggcc gaatgcgaat cgggttgaac
    56701 gccagttcga gactgcttgg gagaatggtt cgctgaaaaa ctccagacgc cgggatctgg
    56761 aggacagtcc cattcaccat cgaaacacag aatcacacgt ttggacacgc gggcactttc
    56821 tccacgacaa ccgcaggctg tgaaaccgcc tcccgcgtga gccgactccg ttcatcagga
    56881 gcactcaaac gtcagtggtg acaggttttg aaccgcaggc agcggaataa gcaaagctaa
    56941 tgccagtcga gcgcattgca atttccggta gcgagaaatg cataggtcct caattgggcg
    57001 caatgcaggt ggcgcgaggt gctctgtaga aattgaggag gcggagggtc gtatctgatg
    57061 cgatacgcag cagtatctaa acgtatacgg gaaagtcagg acaggcgtgc cgcgaccata
    57121 cggcaactcg aagctcgcat ggagctggtc ttacggccgg gtcgatggat tcctggccaa
    57181 gcacgagacg tcaacgatgg tgaggccgtg aaagatcttc caagtggagt tcctgtctac
    57241 cggctgaagt tgttcatgat gaggtctcga tcctgttcga gttgggtcgc caattgttgg
    57301 agcgcctgag aggtggcttc atcaataggc tcttggtctg aggccgtaat ccaccggact
    57361 gacgatccca aagcctcgcc ttcggcagca taggtcttaa agactccgtg cccgggatgg
    57421 gatagatcgg cctccaggtg gactctatac aggtaacgat ccggtgcgcg aagggtgagc
    57481 caggctttca cgaccatttt gagttcagca ggatctgttc cgatcgctct aaaggtctgc
    57541 cgttcagaaa agtaccgaac gatggcttgg cggagatctt ttgcgggcca atcgagcatg
    57601 gcaatgcccg gcatgtggtc agcaccttcg atggcgagaa acggcacctc aagttgcaca
    57661 gcggcaggaa tcgttatcgt ggcgggactg ttcgaggcag gattaacgtg gattctgtgg
    57721 acacatcccg tcaggagcag gcagaggccc atcacaagaa tcatcagccg tgatgcaatg
    57781 aatcgcatgg ttcgagttta tcggtagttc tggttatcga ggggccgcag gaggaggact
    57841 gagaatatcc aagtcgcgaa tggctcgcgc cgcctgttcc cgataggttc gttcggttgc
    57901 gccattatag gtgtcgatga cgcgctggta ggtggcccgg gattgagcat attgtttctt
    57961 gatcgaaaga tactgtccca gagccagcca gttttgcgcg gcagtttcat tggcggtgcg
    58021 aaggtccgtc cattcacggt cgatctgatt ggtgcccggc tgattgacac gccgagtcac
    58081 gatctctccc agctgagtgg agagttgctc gatggcttcg ttttcacgaa cagcggcagc
    58141 gactcgatca tgcttcaaat gatcgtaaaa cgattcgacg tgacctttga tggtatcggc
    58201 gcgtttctca tggatgtcgt gcgagcaatg cgcaagagag agggctatca cgagcatcaa
    58261 tggtgtttgc cagatcaacg ttctgcatga gcgtatcgcc atcatccctc ccttatgaac
    58321 ggatcagttc gttcggtggt gcttgatgcc tgccgtgatc ctacctgagc cggaggagaa
    58381 aggcgagttg gtagtcggct ttacgaggca gacttaagga acaggacggc gagggggggc
    58441 agggttagcg cgagcgaatg ggatcgaccg tgggcaggaa ccgcgtcggc cgagagaccg
    58501 ccgagatttc ccagtccgct gccgccgtat agggaggcat cgctattcag caattctttc
    58561 caatagccgc cctgtggcac gccgactcga tactgcagcc gcgggaccgg cgtgaaatta
    58621 catacgacgg cgatactttc acgggaagac cgtccatggc ggagaaggct gatggtaccc
    58681 gcgtcgacat cctggcaatc gatccattcg aatccgcggg ggtcaaagtc gaactcgtgc
    58741 agggccggtt cagcgcgata gagatgattg agatcggcga cccaccgctg taaaccttgg
    58801 tgcggcggat aattgagcag attccaatcg atactgtcgt catgcgccca ttcgcgccat
    58861 tggccgatct ccccacccat aaaaatgagc ttcttggccg cttgcgcata catatagccg
    58921 aacagcgtgc gcaagttggc gaacttctgc caatcgtcgc cgggcatttt ccccaagagc
    58981 gagcctttgc cgtgtacgac ttcgtcgtgg gaaagcggga gcaagaaatt ttcctggaac
    59041 gcgtagagca tccggaaagt caggttgcgg tggtggtgtt tgcgatagac cggatccagc
    59101 cccatatatt ccagcgtatc gtgcatccag cccatatccc acttcatccc gaacccaagc
    59161 ccgccggcat aggtcggacg cgacacggac ggccatgagg ttgattcctc tgcgtaggtt
    59221 tggacatccg ggtgtcgccg ataaatttcc tcattgagct gacggaggaa ggcaatggcc
    59281 tccaagttct cacggccgcc atgtttgttg gggatccatt ccccctcttt gcgcgagtag
    59341 tcgagataca acatcgaggc gacggcatcc acccgaaggc cgtcggcatg atattgctcc
    59401 agccaaaaga gcgcgctgct gatgagaaaa ctgcgcactt cgttacggct gtaattgaag
    59461 accgccgttc cccagtctgg gtggagaccc tggcggggat cggcatgctc aaaaagatga
    59521 ctgccgtcga atcggctcag cccatgttca tcggtcggga agtgtgaggg cacccagtcc
    59581 aggatgacgc caatattatg ctggtggagc tggtcgatga ggtacatgag gtcttgcggc
    59641 gtgccgtagt tgccggaggg ggcgaagtag ccggtcgttt gatagcccca ggaaccgaaa
    59701 aatggatggt ccatgagggg cagaaactcg acgtgcgtaa accccagccg ctgcacatat
    59761 tcgatcaact tcggcgcagc ctcacgatag ctgagcgagc gattgccttc gccgggaacg
    59821 cgcatccacg agccgagatg cacttcatac acactgatcg gagcctgaag ggcattgtgc
    59881 cgcgcgcggg cctgcatcca gtcgtgatcc tgccagctat aattcagatc ccacaccaca
    59941 gacgcggatt tcggcggaat ttcgttcagg cgggcgaatg ggtcggtctt gatgaggacg
    60001 gccccatgat ttcgtgaccg gatatgaaac ttgtacaggg cgccgatccc cacgccggga
    60061 acaaacccct cccaaatgcc ggatgactga caaggccgga gcggatggcg gtctggatcc
    60121 caatggttga aggtgccgaa caccgagacc tgctccgcct ccggcgccca caccgcaaaa
    60181 taggtgcctt cgacgccctg gacagtcgtt ggatgcgcgc ccagtttgtc atacagatga
    60241 aagtgtgtgc cttcgttgaa aaggtacaga tcctcagggg acaggagact gccgatatgg
    60301 gctggcgctg ccgaggaagg gactacgccc aggggtgcgt tctgtgaatg actccggaca
    60361 ggatccatag gcgcagagta ctgtggttag gggcagggcg tcaatcggac gcttcgaacc
    60421 ggaatggcgg tcagggtccg catgaagttc aggaggatct tggttcagac tagtgacacc
    60481 tctcgatcaa gtgtggtatg aatcatcccg ccgatacgga actttcttcg tccccatcgt
    60541 ctagcctggc ctaggacatt gccctttcaa ggcagtaaca cgggttcaaa tcccgttggg
    60601 gacaccacac tttctcctcg atgctttgtt ggccgaactt tttcc
//
LOCUS       DAOQPD010000015        59205 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_190_length_59205_cov_22.271090, whole genome shotgun sequence.
ACCESSION   DAOQPD010000015 DAOQPD010000000
VERSION     DAOQPD010000015.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 59205)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 59205)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59205
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_190_length_59205_cov_22.271090"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..375
                     /locus_tag="PK063_05495"
     CDS             <1..375
                     /locus_tag="PK063_05495"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96532.1"
                     /translation="AVREAPWLLQEAAVVEWLKRIASTLAGSSSHPVAAVKKFWKEIT
                     NAVAEAETIYTGSLRRLFGELLEAAAISMKRGSPRRAPLVAVSALLNDPSSWMQPARL
                     YSLYRAWTRESLATAEHAKVSP"
     gene            411..1286
                     /locus_tag="PK063_05500"
     CDS             411..1286
                     /locus_tag="PK063_05500"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF025025.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HMZ96533.1"
                     /translation="MTLSIIIPCRNAARTIEETLQALADQKWPAAWEVIVADNGSTDN
                     LARVVAKYTLRIPHLRLVDASARRGASYARNIGVNAATGEYILFCDADDVPAAGWAIA
                     MEKAVRMHGFVASRLEFEKLNSPVVRSARGCTQIVGLQQFRFLPFPHAGSGTLGITRA
                     LHDAVAGFDETIPICEDIDYCMRVQQQGIKLEFVPDAVLHCRLRASKKGVYAQASQYA
                     EYEVYLYKKYGAGHLWEWWRWRKYIQAWRNLLGRMSELLRTPEGKTLFAWRLGRLMGL
                     LKGSLRFWAPPVMVE"
     gene            1303..2034
                     /locus_tag="PK063_05505"
     CDS             1303..2034
                     /locus_tag="PK063_05505"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013672.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HMZ96534.1"
                     /translation="MSLQSFLSTSVRKVLGSLTHVVTPSAVLALTFDDGPDPENTPKV
                     LALLEKYQARGTFFVVGQAAAVQPALVQRIAAGGHAIGIHSWDHRAFPGLTSRERRRQ
                     IRECERALRPYVSPLFRPPYGEQTVMSRLEAFMMGYEVVGWNLNSGDWYESQSSVMGK
                     YLLEMVSPGGIVLFHDTLYDKGTPAHGTDSEHTSWPDRQAMLDALETMLDRLSGSYRF
                     VTVPELLQAGRPRRSFWFKPSLATA"
     gene            2075..2890
                     /locus_tag="PK063_05510"
     CDS             2075..2890
                     /locus_tag="PK063_05510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5672 family protein"
                     /protein_id="HMZ96535.1"
                     /translation="MSSVAVVVPGYNRAEFTEDEEISFRHLEHYLGRYDKFLVVPQSL
                     AIERPGFHIQRFPDSYFGSAIANARLMLSPTFYGAFQSYRYVLIYQLDALVFSDRLME
                     WCASDWDYVGAPWLKCADSPWVGASRVGNGGFSLRKVSSFLRVLSSDAYWVDPEVYWQ
                     RITTGQSWYVKSVNLPRKWYKQIKRFNNVKRELERWHLRPDGTKNEDHFWADEAVRYD
                     AQFKVAPFHVGLDFAFEVVPRHCFELNQNRLPFGCHAWPRYDRSFWEPYLIKP"
     gene            2907..3791
                     /locus_tag="PK063_05515"
     CDS             2907..3791
                     /locus_tag="PK063_05515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HMZ96536.1"
                     /translation="MNESELQQASPLTAGTLAPAVRTPTVKIRPSRGLFHLDLQSVWQ
                     YRELLLFLIWRDTKVRYKQAVIGAGWAVFQPLISMLLFTVLFSYLAKLPSDGVPYPLF
                     AYAGLLPWNFIAQATSRSGTSLVGESHLISKVYFPRLIIPLAAASAPAVDLLCALLMM
                     IPLMLWFGVTPGWQLLFFPVFVGIALLAALAVSFWFSALHVKFRDVGHIIPFFVQFWM
                     FASPVVYPASLIPEKWRTLYSLNPAVGVVEGFRWSLLGQRPPSLETILPSVGIVLVLF
                     VSGIVYFKRMERTFADVI"
     gene            3791..5050
                     /locus_tag="PK063_05520"
     CDS             3791..5050
                     /locus_tag="PK063_05520"
                     /inference="COORDINATES: protein motif:HMM:NF012235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ96537.1"
                     /translation="MAEIAISARHVSKEYVIAEINHDTLRDRIAHGCRSLLGRRAAKS
                     VPPKSFQALNDVSFNVMEGEVLGVIGHNGAGKSTLLKILSRITEPTGGEVDLYGRVTS
                     LLEVGTGFHAELTGRENVYLNAAMLGMRKVDINKRFEAIVEFSGTQQFIDTPVKRYSS
                     GMYVRLAFSVAAHLDPEILIVDEVLSVGDGAFQKKCLGKMDEVRRDGRTVILVSHDLP
                     VVASLCQRAILLRHGRVVGDGQPQQIIEQYMSEAFTGTGVSLADRTDRYTKGELTVQA
                     ITFLDDKLNPLQPALSGQHLVIRVQYKCHVRKAFKDMRVMVVINRDERTSCIFSTDLV
                     SHTPLDLEGSGYVDFHVPHLPLCGGRYFLHAAIENNTMTQDWVQYAAELQVLDGDYYG
                     TGRMYPHDGWRGKGMFVDHSWRFERTS"
     gene            5350..>6721
                     /locus_tag="PK063_05525"
     CDS             5350..>6721
                     /locus_tag="PK063_05525"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ96538.1"
                     /translation="MLVAICLLTAGVFALDVAMSLGHVIWLLYALPLWLSVRLTSPAA
                     PLRYASLCTLLLGTAVWVAPPGIELTTAVMNRTLGLALLWGMAVLLSQRRESETALRS
                     ANSRLEQRVAEQTQDLSAANDRLSVQLAEQRQVEVALRESRQRFELAAECADVGVWEW
                     DLVTKSAYYSPRWKTQLGCTESDIGPTVADWESRLHPDERAQVLATVTLFQQGYTKQY
                     RLDHRLRHQDGSYRWMAALGAGVYDEQGCMIRMTGIHLDITVRKQAEEARRESEERYR
                     ELVEQAGDIIYRTDAAGRFTYCNPTSLRILGYFPEELLGRHYLDIVEPQSRAQAERFY
                     GRQFIRKTLRTVYELPVVTKDGREVWLGQHTQLLMEGNTVHGFQVVAREVTERKRVEQ
                     ALRESEERFSKAFHSSPAGMAISRLKDGRVLDVNEAFVRVSGFSREELIGMSSLDIGI
                     WINPDDR"
     assembly_gap    6722..6821
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <6822..9530
                     /locus_tag="PK063_05530"
     CDS             <6822..9530
                     /locus_tag="PK063_05530"
                     /inference="COORDINATES: protein motif:HMM:NF013736.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ96539.1"
                     /translation="LIGMSSLDIGIWINPDDRRHLAEALRRDGFLRHLEKEFRTKSGE
                     LRHGLFNVEPVCIGHENCVLTLVLDITRRTEAEAALRRSQTVLQAHQHALMRLTKSQH
                     IGSGDWPSALKELMQTSAEAMAVDRASVWLLDRTGAVLECVELYQRNEARHSRGARLD
                     VAQYPRYFAELLEEQVVDAHDVASDPRTAELLQPYLQTMGIASLLDVPIFFGGRLAGV
                     VCHERLGSARPWSNEDAQFATSIGNLVTLAYESKQRREAESALVTAKEAAEFASRAKS
                     DFLATMSHEIRTPMNAIIGMADLLSETPLSEDQREYVQIFRDAGGNLLSLINDVLDLS
                     KIEAGHLDLDLTDFDLSDLVQRAAELVAVRASEKNLELAYQIQPDVPTSLVGDPNRLR
                     QVLLNLLGNAIKFTDQGEVVLRVECDPHAEGPGSLLFTVRDTGIGIPRDKLAVIFERF
                     TQVDSSMTRPYSGTGLGLTISRRLVERMGGRMWVESEPGRGSTFSFTAKFAAHAQPAS
                     PVPTAQWEQLAGLRTLIIDDNATNRLIVRETLSSWGIPSAEAAGGDEALLELRRALTA
                     GMPYRLAILDVRMPKLSGWQVAETIARSPGLAGLSIIMLTSERRAGDQARAREHGVVR
                     YLTKPFRRSDLFNAMMAVLGKTAPAGNPESEAPSQPKFAGDDQSGLKILLAEDFLDNR
                     RMMEFYFKATPHRVATAANGQIALEMFMHGSYDLVLMDIQMPVMDGYAATRAIRAWEK
                     DQRRRSTPILALTANALQSEVQRSLDAGCTAHLTKPIRKAQLLEAIQLYFQTASSQPP
                     VPAYHEEPAVLHVNVELEALMPGFLEHRRQDLIQMTAALDREDFEVMREIGHGLKGAG
                     GTYGLEAITAYGRSLETAASRKDGPALREILERLRRFLDRLQLIYV"
     gene            9543..10937
                     /locus_tag="PK063_05535"
     CDS             9543..10937
                     /locus_tag="PK063_05535"
                     /inference="COORDINATES: protein motif:HMM:NF025885.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ96540.1"
                     /translation="MRVLLVEDHPDVRLLFEQVIGARGHEVTACADGESAWEAYGKRS
                     YELVLLDWELRGGGMDGLQLCRRIRSGPGGDRCVIVMITGHDSPESLRAALQAGVNDY
                     LAKPVGVEFLRLRLTIAEQWVESVRRRFAAEDQAQALQSQLADHGKFHDLIGRSPSMV
                     VLYEEIQQIAAVDATVLIEGETGTGKELVARAIHLSSRRAPHTFLAVNCAGFTDSILG
                     SQLFGHKKGAFTGAIDNQEGVFEAAQGGTIFLDEIGDISPAVQTSLLRVLQEREVTRL
                     GESKPRKVDVRVVVATHHNLVEDVEKGTFRRDLLYRIKVARLQLSPLRERPTDIPLLV
                     HAFLGQFRSVMEKPVLHVSPEALQVLTSYSWPGNVRELKSAVESALIHCKGTVVRPED
                     LPPEIRSPQPQATYVPLQRQDERTRMLGALQQTGGNRSEAARLLGMSRRTFYRRLAEY
                     DVAASAEPGAESFL"
     gene            11258..11542
                     /locus_tag="PK063_05540"
     CDS             11258..11542
                     /locus_tag="PK063_05540"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96541.1"
                     /translation="MVEQQGPSQKEGSMEVEGFLLSNDMDQEVLVTIPPSSVGPFDQP
                     AVKERIDGYWIEMSRLPNRRWSDRTRAVGAVLTYLQGLSAISSGFATHTR"
     gene            11579..11896
                     /locus_tag="PK063_05545"
     CDS             11579..11896
                     /locus_tag="PK063_05545"
                     /inference="COORDINATES: protein motif:HMM:NF012422.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="HMZ96542.1"
                     /translation="MWNDQNLLRSAREDNARDGAAGLSVVPGVSLTAKRRPEDLTPRE
                     QEILQLVWAGLTNRTIAEQLHISIKTAEAHRANMMKKLRVSNIAQLLKTALEEGLLAT
                     HAG"
     gene            12046..12438
                     /locus_tag="PK063_05550"
     CDS             12046..12438
                     /locus_tag="PK063_05550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HMZ96543.1"
                     /translation="MVEQRIEEITRANLAFYAAFESLDMLQMDKVWAHLEYVTCIHPG
                     WTLRSDWPAVRDSWVLIFNNTFSMKFELSDVQVQVAGDLGWVICTEHLTSRQDDQPVE
                     TRVLATNLFERIGDEWLMIHHHGSPVMG"
     gene            12620..12949
                     /locus_tag="PK063_05555"
     CDS             12620..12949
                     /locus_tag="PK063_05555"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96544.1"
                     /translation="MAQITTLSDESCRQTVRGQLESILVEEGERPEMATRLAVNTTVV
                     LATGSLGPRPFGVSSPSGTDYSFFVQRKGESCLLRLYGRQKGFTRYTNNLTYISTRPL
                     EGCACAE"
     gene            13343..13588
                     /locus_tag="PK063_05560"
     CDS             13343..13588
                     /locus_tag="PK063_05560"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96545.1"
                     /translation="MMVKGFLLKDREEQEYLLAIQPATHGMFERLIVRQKIDGCWVEL
                     NGNAQGTWQPRTQAITAVLGYLQRLWDTSKPVAAREN"
     gene            13645..13983
                     /locus_tag="PK063_05565"
     CDS             13645..13983
                     /locus_tag="PK063_05565"
                     /inference="COORDINATES: protein motif:HMM:NF012422.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="HMZ96546.1"
                     /translation="MQAEKQDRGGDMMSGSSMKSREMSDDPEAAALKRKPEDLTPREL
                     EILRLIWDGHTNRSIAELLNISMKTADTHRANMMKKLRASNTAQLLKAAIEGKLLHIH
                     EGARRSDGAK"
     gene            complement(14067..14303)
                     /locus_tag="PK063_05570"
     CDS             complement(14067..14303)
                     /locus_tag="PK063_05570"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96547.1"
                     /translation="MSGQSCLIDGCQARVYAPAGTRSICKDHFLGFLTWRRRRGPQMF
                     RKYAGMTMEERDVIAGEWLQTLGTKDIPHPIPGL"
     gene            14536..14790
                     /locus_tag="PK063_05575"
     CDS             14536..14790
                     /locus_tag="PK063_05575"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96548.1"
                     /translation="MIMQVISVVGALMVLIAYGLIQAGTWRELDAGYLALNIIGSLLL
                     GIVAIEDRRVGFVLLEFAWAGIALVGVARSLRARRAARGL"
     gene            14845..15327
                     /locus_tag="PK063_05580"
     CDS             14845..15327
                     /locus_tag="PK063_05580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96549.1"
                     /translation="MAGLLSADDVFEQAKNAAVGATNADEKALQIDYEALQLKFRAAL
                     GDRKVARCHINKFLPEGYEDQGRFNLILLTAGNVIFDIVIGDSYFRYDVVSVSQLDKV
                     QVIDAMWDNREKRREEPFLSLRLMHAEETHLLLALDDEERKSLLGFASAVSAVRNPEK
                     "
     gene            complement(15509..>16342)
                     /locus_tag="PK063_05585"
     CDS             complement(15509..>16342)
                     /locus_tag="PK063_05585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage T C-terminal barrel
                     domain-containing protein"
                     /protein_id="HMZ96550.1"
                     /translation="LTHKGKMLGYFRVYVQSDAVWIEDVGEVGEATFQALRKFLLYGT
                     KAKMENCAESWGLLLVSGPKSAEVVSAAFGVEVERLQLLQTIQTTVGGQPALIMRTEE
                     TGEQDLEILMPADGLTAAWNQLMTAGAPFGATPVGSHARELLRIEAGLAKAGPDLNEE
                     IVPPEANLEGKAFSLSKGCYPGQEVVARMDTYGNVRRHLVGLLIQDQTVPAHGSKLFS
                     GDREVGWISSAVLSPQRHAVLAFGFPLRDFSAPNTELTVEVAGTRHQATVHTLPFYQR
                     P"
     assembly_gap    16343..16442
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<16443..16792)
                     /locus_tag="PK063_05590"
     CDS             complement(<16443..16792)
                     /locus_tag="PK063_05590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HMZ96551.1"
                     /translation="MNTTIVVAVTDIFFYTKVRDALRPQGYTLERIRNQDEVAEKMTS
                     TQPAALILNMNDLAVDAFKALETIQSNPALRSLPVLAFVNHEEVDTWRRAKELGVTKV
                     VSRNEFSARTKDLV"
     gene            complement(16808..17323)
                     /locus_tag="PK063_05595"
     CDS             complement(16808..17323)
                     /locus_tag="PK063_05595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ96552.1"
                     /translation="MDVQDFLIQGDGSEEDKREAWQLFQQAYELQMKGQLEEAVSLYK
                     LSLATHQTAEAYTFLGWTYSFMGKLDEAIEECHKAIACDPHFGNPYNDIGAYLIEKGD
                     LDEAIPWFQKAMQATRYESPAFPHLNLGRVYERQGKWSEAIDCYKQALALNPDYALAK
                     KALGRLISSLN"
     gene            complement(17462..18262)
                     /locus_tag="PK063_05600"
     CDS             complement(17462..18262)
                     /locus_tag="PK063_05600"
                     /EC_number="2.4.2.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide-dependent adenosine diphosphate thiazole
                     synthase"
                     /protein_id="HMZ96553.1"
                     /translation="MGKPKPAPLRERDITRQIAREYYNEFDQLIESDVIIVGAGPSGL
                     ICAHDLARMGVKTLVVEQSLALGGGFWSGGYLMNKATICAPAHKILKEVGVPCKQIKE
                     CPGMYMVDPPHATGALIAAAYDAGAKIMNLTRVVDLILRREGVLEGVVVNSTTAEMAG
                     HDIIHVDPIALESKIVVDATGHDAVVVNLLHKRGLYQQVPGNGAMWVSRSEEEVMDRT
                     GEVSPNCFVIGLAVAAVFGTPRMGPAFGSMLLSGRYGAELIREKLKKR"
     gene            complement(18402..20318)
                     /gene="thiC"
                     /locus_tag="PK063_05605"
     CDS             complement(18402..20318)
                     /gene="thiC"
                     /locus_tag="PK063_05605"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HMZ96554.1"
                     /translation="MSEAHTQNGSSNGHGAKPSTARLTTTPFAASRKVHVEGSQPGVR
                     VPMREISLTPTHSTNGNGGTPNQPVTVYDTSGPYTDPNVTIDVRAGLPPLRRMWIEAR
                     QDTEELPQVTSQYGRQRAADPKLADLRFTHIRKPLRAKAGRNVSQMHYAKKGIITPEM
                     EFIAIRENQARARAKDLMASSNGHGGGVSQHPGQAWGARIPSLITPEFVRDEVARGRA
                     IIPNNINHPESEPMIIGRNFLVKINSNIGNSAVASSIEEEVEKMIWSIRWGADTVMDL
                     STGKNIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVD
                     YFTIHAGVLLRYVPMTAKRMTGIVSRGGSIHAKWCLSHHQENFAYTHFEEICEIMKAY
                     DVAFSLGDGLRPGSIADANDEAQFAELETLGELTKIAWNHDVQVMIEGPGHVPMHMIQ
                     ENMEKQLKECQEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGCAMLCYVTPKEHL
                     GLPTKEDVKVGVVTYKIAAHAADLAKGHPGAQARDNALSKARFEFRWEDQFNLALDPE
                     TARSYHDATLPDNAAKVAHFCSMCGPHFCSMKITQDVRDYAAQKQLEEQQAIQIGMKE
                     KSEEFKKAGSEIYL"
     regulatory      complement(20410..20512)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(20597..21154)
                     /locus_tag="PK063_05610"
     CDS             complement(20597..21154)
                     /locus_tag="PK063_05610"
                     /inference="COORDINATES: protein motif:HMM:NF023696.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3617 domain-containing protein"
                     /protein_id="HMZ96555.1"
                     /translation="MKKRMTPTLGRFVYLVACGLLSNPVLLWPTSGAQAESFNAKPGA
                     WEMTFTTQSSGMLVPPDVLAKMPPEQRAKVEQSMQARSGKPKTHSVKTCLTKEDLDQN
                     RIIKENDDDEPGCKTSVVSKSSAKLVLERTCPAPQASTSRMSVEAQTAELLVGSMDTD
                     RPRAGKVHIDFKSRWLGANCAGIAE"
     gene            21324..21920
                     /locus_tag="PK063_05615"
     CDS             21324..21920
                     /locus_tag="PK063_05615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3365 domain-containing protein"
                     /protein_id="HMZ96556.1"
                     /translation="MNGRNFWIGLVVGASAMGILGQWGPAVAGKDAIQPTCIPAAAVA
                     EYLHSVIQADRTFYTTDVVERMQMRGIAFAAENWRETSRLPLPAQYLLETGRLVAAGR
                     SGVQYRLISNWAINAKNRPMTDFERAGLTEILVNPDQPYTAVTTEGGAPVFQAIYADK
                     AASQSCVGCHNAHPNSPKKDFKPQDVMGGILLTIPLPQ"
     gene            22145..23272
                     /gene="nadA"
                     /locus_tag="PK063_05620"
     CDS             22145..23272
                     /gene="nadA"
                     /locus_tag="PK063_05620"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HMZ96557.1"
                     /translation="MDSTERLQVKTVTTLPRPITDYQSLSAEELFERTRAAKRALGDR
                     VMVLGHNYQRDEVIQHADFRGDSLILAQVAEQRSDRPYVVFCGVHFMAETADVLSRSN
                     QTVILPDMAAGCSMADMAAIEQVEQCWDALGRVVPVEETVMPAVYVNSAAILKAFCGE
                     HGGLTCTSSNARKVIEWSWARREKILFFPDEHLGRNTANKMGIPREQMIVWDPYMPRG
                     GNSVEAIQRAKLILWKGHCSVHQMFQPSHIDYVRKKHPEVKVIVHPECHEDVVNKADL
                     VGSTEYIIRTITAAPAGTTWAVGTELNLVNRLKHEQADKKIFFLSSTVCQCATMYRID
                     APHLCWALENLADGHVVNRIVVPDDEKQLAKVALDRMMALS"
     gene            23535..26354
                     /gene="ileS"
                     /locus_tag="PK063_05625"
     CDS             23535..26354
                     /gene="ileS"
                     /locus_tag="PK063_05625"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HMZ96558.1"
                     /translation="MDYKSTLNLPKTDFPMKANLPQREPEMLARWAQERLYERIQESR
                     QGREQYILHDGPPYANGRIHIGHALNKILKDIIVKSKTMSGYQVPYVPGWDCHGLPIE
                     HQVLKELGDKKRDLDALAIRKLCQEYAAKYVAIQREEFQRLGVLGEWQQPYLTLNPAY
                     EGTIIREFGRFVERGGVYKGLKPVLWCTQDQTALAEAEVEYDDHTSPSVYVKFPLVSP
                     PSVLSKRFGPVSFPVEATRASVLIWTTTPWTLPANQAVCLHADIDYAFVLVGDELLVM
                     AEKLVESVAKACNIPTYTIVAVKKGREGFEGLEAQRPLTTGLSPLLLGDFVTLEQGTG
                     CVHIAPGHGMEDYLLVLDHNAKASVGERLEILAPVDNGGKFTEAVPEFAGQHVFKANP
                     KIVERLKGNGRLLGHGSLNHSYPHCWRCKQPVIFRATEQWFVSMETNDLRKEALAEIE
                     RVRWIPAYGRDRINGMIENRPDWCLSRQRVWGTPIPGFTCLTCGKVLAHPRVIDHVAD
                     LIGQHGTDYWFANQAGALLPAGTQCEGCGGTDFEKERDILDVWFESGVSYAAVLKPRQ
                     WYPADLYLEGSDQHRGWFHSALLSGVITDHRAPYKAVLTHGFVLDGAGRKMSKSAGNV
                     VAPQDVIKQSGAEILRLWVSAQDYREDLRISQEILNHLIEAYRKIRNTCRFLLSNLYD
                     FDPAQHRVPFEQLPELDRWALMRLSDLIPRVRKGYDEFEFHTIFHALNNFCSVDLSAV
                     YLDILKDRLYTFRKDSPLRRGSQTVLFDIVVALTKLMAPVLSFTAEEIWRTLPESVRT
                     EAKADSVHIAMFPEVDPRWADPMLAQRWEQVLEVRSAVQAALEVKRREKVIGAPLEAR
                     VVIEANSERYEFLKRYEQELSSFFIVSDVVLTQAGHLAESPGYSVTVDKATGAKCERC
                     WNYRSAVGTSADHPTLCDRCIEAVR"
     gene            26351..26872
                     /gene="lspA"
                     /locus_tag="PK063_05630"
     CDS             26351..26872
                     /gene="lspA"
                     /locus_tag="PK063_05630"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HMZ96559.1"
                     /translation="MSQSIRYLLLASLSLAIVVLDQVTKVYVMETMRLHESIPVIANL
                     FSITYIRNPGAAFGFLSSSSSSFRFVFFGLTSIFAVGLLGMIMVRMPKEDWMGRLSVA
                     GILGGAIGNLLDRLRYGEVIDFLDFYVNGYHWPAFNVADSAITVGVVFLILHFATEKE
                     PADQPVASEQPPS"
     gene            complement(26891..27157)
                     /locus_tag="PK063_05635"
     CDS             complement(26891..27157)
                     /locus_tag="PK063_05635"
                     /inference="COORDINATES: protein motif:HMM:NF021169.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2024 family protein"
                     /protein_id="HMZ96560.1"
                     /translation="MASNMDSVHVYDTWVKGKNGKLHFDVMTTSQEKALALAKQYLVG
                     IGEPQAVITLKECQFCHSEPLAMFSVKQQRQFREQGGFIITLPV"
     gene            complement(27186..28061)
                     /locus_tag="PK063_05640"
     CDS             complement(27186..28061)
                     /locus_tag="PK063_05640"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: protein motif:HMM:NF001390.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HMZ96561.1"
                     /translation="MMNWGPELAVILGIIEGLTEFLPVSSTGHLILVGHALGFTGDIA
                     SNVEISIQLGSILAIIAYERAKLASLASHALREQQEFRSLIATRGTKSWATTLQESIN
                     AQPNLWFVIGLGLAFLPAALVGFVAHKSIKAYLFSPTTVAISLIVGGVIILVVERMQS
                     RVRVKELLQVTPRSALLVGLAQCASLIPGMSRSGSTIVGGLLAGLDRRVATEYSFFLA
                     LPTMIIATIYQMLKSQASFSQDDYVALGIGLVVSFVVAWAVIAAFLTFVQRHSLSVFA
                     YYRMVLGVIVLLVVR"
     gene            28313..29026
                     /locus_tag="PK063_05645"
     CDS             28313..29026
                     /locus_tag="PK063_05645"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HMZ96562.1"
                     /translation="MRHVWVAGLALMSAMAVSGCVSDKKYHEALADADATRGELERAR
                     AQKNALEQQVKTLKDLNAKFGSESQIARDELQRIQHGRDKERDTIDVRTKELEDKVKQ
                     LSAQNRSVKQEYEEARRHNEQLKSLVARYQKEMKDRSRSLSSGMESPALTAPLGGGGA
                     SSKAAPAPAPFEAPAAPLLNINKAPSSDLVLTLGITQDVADRIVSNRPYRVKGELVAK
                     NVVTKDVFDDIKDRITVSP"
     gene            29215..30498
                     /locus_tag="PK063_05650"
     CDS             29215..30498
                     /locus_tag="PK063_05650"
                     /inference="COORDINATES: protein motif:HMM:TIGR01730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HMZ96563.1"
                     /translation="MRRVSIIVGVLALGLAIAGYVFFNGERKVPLRFRTVPVERGSVV
                     SLVTATGTINPITTVQVGSQVSGMIESLHADFNSKVKANQVVARIDPFPYQARRDQAV
                     ASLANAKAAFEKARIDLAQRRRELDRAKSLIGQQFISQNEVDVALTASEGAVAQLKVT
                     EAAVKQAEAMLQAAELDLKYTVIRSPVDGVVISRLVEVGQRISASFSIPTLFLIAEDV
                     TKMQVDTNVSEADIGGIVDGKAASFTVDAYPGEAFQGRVRQVRNAPINIQNVVTYDVV
                     VEFENPEFRLKPGMTANVSIVVNKRENVLKVPNAALRFVPPKAVRDEKGEAGPRRDGE
                     RAGGRPTIASGSPESGNRQWGVWRLDGAGELERVPVEMGISDRSYVEITAAGIQEGDQ
                     VVTGIESPRGERKSGELPPGFGGGQQRGGRRDRGM"
     gene            30501..31253
                     /locus_tag="PK063_05655"
     CDS             30501..31253
                     /locus_tag="PK063_05655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ96564.1"
                     /translation="MVETVACDPVCEGTMAPLIVCEDLWKIYRIGDVEVQALRGINLT
                     IDRGEFVAVMGTSGSGKSTLMNLLGCLDKPSRGRYRLDGLDVSTANPDLLADLRNRQI
                     GFVFQNFNLIPRTSALENAQLPLFYRGVSIKEQRRQAAAALQRVGLAGREQHYPAQLS
                     GGQQQRVAIARALVGAPSILFADEPTGNLDTASSREIMDILEHLNREDGITIILVTHE
                     PDIAAYASRELVMKDGQIVQDVRREPHLSAVT"
     gene            31260..32495
                     /locus_tag="PK063_05660"
     CDS             31260..32495
                     /locus_tag="PK063_05660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HMZ96565.1"
                     /translation="MPAFVLLTVMTALRILSRNRLRAGLTMLGIVIGVGAVIAMVSIG
                     QGARAAVQAQVASMGTNVIVIMPGSTTVSGVRGAQGGAVTLTINDAAELKKRSPLLSD
                     TGWAKRDVMQIVNGNRNWNGPVNGVSPSYLTIRDWSFTSGGPFTQTDMDSAARVALIG
                     QTTLENLFDPGEEAMGATIRIKNVPFQVVGVLAPKGQSAQGTDQDDVIFIPFTTAERR
                     VFGSQFLGSVGALFASTEQSGDLPEAVEHIRETLRLRHRLEPDQADDFTIRTQVDIGK
                     VQESTSQTLTVMLFAIASVSLLVGGIGIMNILLVSVTERTKEIGVRMAVGAKRIHILT
                     QFLIEAMTLSLFGGLIGVIVGIVGARLTTVIAGWPTMISVDAVLTAFLFSLAIGLFFG
                     LYPANKAARLNPIEALRYE"
     gene            complement(32568..33806)
                     /locus_tag="PK063_05665"
     CDS             complement(32568..33806)
                     /locus_tag="PK063_05665"
                     /inference="COORDINATES: protein motif:HMM:NF023299.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3391 domain-containing protein"
                     /protein_id="HMZ96566.1"
                     /translation="MTYRPITIDALRIGMHVAKIDVAWFRSPFMRHSFLIRTDEQIEK
                     LRRAGVKQVSIDPSRGLDLQDPMAPSQAPLPVAAQPATSQMGKSVEIRSLATMTQELL
                     AARSARAKLEESVHSAFSRIAKTGVVDPEEASHAVHAISAVAQALNTSALFMVFSQGR
                     EANAPLSQHALATCSFSMILAHAADYNLMAIQELATGALLHDIGLLQVPPAILRRVHD
                     TSTTVSEQNRLTYEAHARSGAILLERRGGFTKPVEQIVAEHHAYLNGSGFPAETGGAF
                     TSDMTRIVMVTDRYDELMTGFGGASPLTPHQSLQRLYQEGQEGRYESRLISLFVKVMG
                     IYPVYSYVQLTTGERAIVSVINSGKLHQPIVTITHDPSGEPYIVPLVIDLANQDEEAP
                     PRGVRSVLGTIPEEFQRAYH"
     gene            complement(33862..34425)
                     /locus_tag="PK063_05670"
     CDS             complement(33862..34425)
                     /locus_tag="PK063_05670"
                     /inference="COORDINATES: protein motif:HMM:NF017663.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HMZ96567.1"
                     /translation="MERAPLIPTQSNRNRHALSFPTPAGTGLSVTIDSITLTLPVPPS
                     INHQYATVNGRRLLSAKGRTYKDFVGQQIVVALAQSPHRATLRQTLQQASLSLSIHFF
                     FASALRRDTDGGLKIAQDALCEGLGLNDNRVVETHLYKHQDRDNPRMEIRLSVAPSTA
                     PDPFFPASLKAQVAVIPKPPIDNGQDR"
     gene            complement(34518..34958)
                     /locus_tag="PK063_05675"
     CDS             complement(34518..34958)
                     /locus_tag="PK063_05675"
                     /inference="COORDINATES: protein motif:HMM:NF014439.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96568.1"
                     /translation="MFAGEHLCKVDEKGRFLIPSPLRERFQAEGNQVMFLKNTEQTLW
                     MYSAKEWEQVLERTRATLDEDQTRLFMHHVMAQAGASDIDKAGRVLIPSRLRKLVPMD
                     EDQELVLVGMYHRLEIWGPSEWRRYLTRNEDRAEQDMAKIQNLL"
     gene            complement(35036..35380)
                     /locus_tag="PK063_05680"
     CDS             complement(35036..35380)
                     /locus_tag="PK063_05680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HMZ96569.1"
                     /translation="MPIYEYRCRQCGKRTTRLILNANSVPQQTCAHCQSADMERLLSR
                     FASPKSEEARLEALSDPSNLSGLDENDPQSMARFMKKMGQEMGEDLGDDLDAAMEDGQ
                     APASGIDGTDFD"
     gene            complement(35384..36175)
                     /locus_tag="PK063_05685"
     CDS             complement(35384..36175)
                     /locus_tag="PK063_05685"
                     /inference="COORDINATES: protein motif:HMM:NF039185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HMZ96570.1"
                     /translation="MDFLRQASRLLLPMDCTTCAQPLADDPVPFFCRRCWELIRPLRG
                     PSCPRCHRPFASPSALTYSPTHECQDCRTREPYYSQVWAPYAYCSPLQDAIALFKYRG
                     KVALADALGVLLLQAIPDRLDVDVLMPIPLHPTRLRQREFNQSLLIADRIGSARRLPV
                     SYRNLIRTVDTAPQTSLPRAARLQNLRKAFAIRQPKEITGARILLVDDVFTTGTTASE
                     CARVLLTAGAKQVAVLALARSADAGMVPDTWLPPSALNQTEFQRA"
     gene            36413..37087
                     /locus_tag="PK063_05690"
     CDS             36413..37087
                     /locus_tag="PK063_05690"
                     /inference="COORDINATES: protein motif:HMM:NF012235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ96571.1"
                     /translation="MSVHNLSKEYRRGGTVLCALQGVTLEVKAGEFCAFVGPSGCGKS
                     TLLNLIGGLDQPTSGTIMIEGRAVTDASATEWTRLRRELIGIVFQAFHLIPGLTVAEN
                     VALPMLLKGEQGRAVTDRIDEVLQAVGMEARRSHRPSELSGGEQQRVAIARAIVHRPR
                     LILADEPTGNLDSKQGADIVNLFRTLPQRFGHSVLLVTHSDSAAEAADYVWHMRDGRL
                     VNRIAH"
     gene            37161..38087
                     /locus_tag="PK063_05695"
     CDS             37161..38087
                     /locus_tag="PK063_05695"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HMZ96572.1"
                     /translation="MSLSMTIAGVTFPSCLMNASGALCMTREELLALGRSRAGAIVTK
                     SMTVEPRGGNPEPRYYGFPGGSINSMGLPNLGYLAYADLIPELKQFGKPVIASIAGLC
                     EDDFLTMARVINHAKPDLIEVNLSCPNIPGKPQIAYDPVDSERLLKRVRPLITVPMGV
                     KLPPYFDPAHHAVMAEVIGRCGVDYLNLINSVGNGLVIDPKRETPVIKPKGGFGGLGG
                     SLIKPVALANVRAFWKLLGGRIPIIGTGGVVQGLDAFEHVLCGASAVQVGTVLVEEGV
                     GVFERLERELEAELSSRGARRVEDYRGRLKEL"
     gene            complement(38130..38465)
                     /locus_tag="PK063_05700"
     CDS             complement(38130..38465)
                     /locus_tag="PK063_05700"
                     /inference="COORDINATES: protein motif:HMM:NF012422.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ96573.1"
                     /translation="MALRKRPQAKKSSKTTKAAPAAKKRKPVKLAKASPGRTRRSDGL
                     TPRQKEILKLVSQGNTNRDIARRLDISVRTVEVHRFNLMRRLKVRNVAQLLRQALQQG
                     FLPKNFAFR"
     gene            38564..41218
                     /locus_tag="PK063_05705"
     CDS             38564..41218
                     /locus_tag="PK063_05705"
                     /inference="COORDINATES: protein motif:HMM:NF024116.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HMZ96574.1"
                     /translation="MSLFHSSLLRVCASLGWTHLSTHPGRTALTMFGVGLGVAATIAV
                     QTANVEVLRSFEESVLTVAGPVTLEVSAGETGLDERLISTVRTVPGVLSARPVLEVGV
                     RVTDGRSPRQSFSILGLDLLEELSPEGGRVVSPANRGEGAGERMPLEDLLARNGLLIG
                     HALASELSLAPRAQLALQSGDQHVSVSIIGVMGRRPGGPSPWDRIAVMDIAAVQRTFG
                     LIGRLDRIDVVTTPTSSVEQVAEAIGRVLPPATTVRRPIQRSQQVESMVGAFQLNLSV
                     LSMVGLLVGIFLIYNTVSFTVAQRRREVGILRAIGMSEPMVVAVFLAEAGVFGVVGGL
                     LGGMLGLLLGDVLVALVGRTIHDLYTPLSHSTGTVGFPVGSGRLLVEAVLIGSGVSVL
                     GALGPSVDAGRTIVVAALAPGEYDVAQRVRAASLGVAGGVLLLIALGCALAGPVGGVP
                     IFGYVATFCLLAGLSCLVPILLQSLCRTRELTTLSQAPTLGGAIRHIAREQTSRGMGR
                     NAVTVSAFLVGVAIMVGVLVMIRSFRDTVEIWIDQTVMADFIVAPAGWPHAVRSGSSS
                     PVLPGAWRARLANAPLVSAVDMYRDLRIDLQGRPVSLVSRDLALHAARSRYLFVTGES
                     APILARAAAGEGAILSEVVANHLALGKGDRLSIVTPKGEQSLEVLGVFYDYATDGGKI
                     VIDRSLYQQWWPDDGVTVFPVYVESGADMGKARMAILGTLAQASQGNLMPTVLSNAEL
                     RQEILRIFDRTFTLTYVLEAIAVIIATLGIINTLVTSVVERRRELATLQALGSSRGQV
                     TALILWEAGYLGLLGTGMGLVGGGALALILIRVINRQSFGWTIQISWPIGLMAEVAAL
                     ALVASLVAGFWPARWAARQPLVEGLRYE"
     gene            complement(41209..42240)
                     /gene="bioB"
                     /locus_tag="PK063_05710"
     CDS             complement(41209..42240)
                     /gene="bioB"
                     /locus_tag="PK063_05710"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004076 - biotin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HMZ96575.1"
                     /translation="MTDFTILADKALRDELLTREECLTVLHTPDTNLLELLQAAFKVR
                     ERYFGKTVRLQMLLNAKSGACQEDCGYCSQSSVSTAPIERYGLLPQDQMVTGARRAAA
                     AKAQRYCIVISGRSPLDREIADIASAVRSIKQEVPIQICCSLGLLNERQAKDLKAAGV
                     DRINHNLNTSEAYHTEICSTHTFQDRLATIRHARTAGLEICSGGIVGMGEGDEDLIDL
                     ALALREVKPDSIPLNMLHPASGTPLEHCTPLTPQRCLKALCLFRFLHPRTELRIAGGR
                     EHNLRSLQPLALYPADSVFVNGYLTTPGQPAAEVWRMIEDLGFDIQVDALPTQGATSS
                     AEPAVGLHS"
     gene            complement(42341..43741)
                     /locus_tag="PK063_05715"
     CDS             complement(42341..43741)
                     /locus_tag="PK063_05715"
                     /inference="COORDINATES: protein motif:HMM:NF024299.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ96576.1"
                     /translation="MFRLLSTIFLVSVGIFLYSYFRELNPGTITVRTSPDAIFELSPV
                     SLVLFSMALGATLVALIVTIKETSHVFMNWRTNRLVRRKEKVDALHRDGTHAFMSKRT
                     ADAVSLFERALVIDPNRTDSLLWLGNIYRSESNFTEAIRLHQQAYRIEERNVEVLLEL
                     AKDLEGARRYEEALQTLQNILRIEPDNLMALIRKRDLQIRLEKWSDALEIQHRLVKAN
                     LPESERRAEANLLLGCMYEVGRQLLERGHPDKARRYFRGAIKKDRTFLPAYIGIGEIL
                     VREGKIKNAVEILKKIYAKTRSVIILHRLEELFLELGEPDEIIRVYQEALQQDPHNAV
                     IQFYLGKLYYRLEMVDEAYDVLSTLDGTQEQLVDYHKIMANLFLRKQHMDEAVGELKK
                     ALGFKKRVVVPYQCTQCHHELAEWSGRCRRCGRWNTYVALPWRDSTKSGADQDGQAAR
                     LPAVPYQGIASPFETV"
     gene            complement(43743..44165)
                     /gene="rsfS"
                     /locus_tag="PK063_05720"
     CDS             complement(43743..44165)
                     /gene="rsfS"
                     /locus_tag="PK063_05720"
                     /inference="COORDINATES: protein motif:HMM:TIGR00090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HMZ96577.1"
                     /translation="MSVSETKAKALAVAAAILDKKATDVLILHIAKLTSIADYLVIGS
                     GESERQARAIADHVGDVLKAQGHPPLGIEGASSAKWVVMDFGDVIVHIFQKDIREHYA
                     LERLWGDAGQVKLPEERAVKVTPPARTKARPARTRKRV"
     assembly_gap    44462..44561
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(44790..45911)
                     /gene="proB"
                     /locus_tag="PK063_05725"
     CDS             complement(44790..45911)
                     /gene="proB"
                     /locus_tag="PK063_05725"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HMZ96578.1"
                     /translation="MRDELLKQARRVVIKIGSSLVASRESGLSTERIERLASEIAHVR
                     AQGREVLVVSSGAVVSGIKKLELREYPKSLPVKQAAAAVGQSLLMWAYEKAFERLSLR
                     VAQVLLTHEDLADRRRFLNARHTLTTLIKFGVIPIINENDTVAVEEIRVGDNDTLAAQ
                     VAHLVDADLLIILSDVDGLFTADPRKDLQATLIPLIQEITADIEQRAGMSSTFEGTGG
                     MATKVRAAKKVGEYGVATLILNGTRTGLLPDVLSGQPGGSLFLGRERRMNSRKHWIAF
                     TLRPRGHVQLDQGAVDALVRNGKSLLASGIRDITGQFEAGDPVTCAGPDGKECAKGLV
                     NFSSTILTRIKGLKTADIQKIPGLQEYEEVIHRDNLVLL"
     gene            complement(45893..46924)
                     /gene="obgE"
                     /locus_tag="PK063_05730"
     CDS             complement(45893..46924)
                     /gene="obgE"
                     /locus_tag="PK063_05730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HMZ96579.1"
                     /translation="MSTFVDQVQILVKAGHGGNGACSFRREKFVPRGGPDGGDGGDGG
                     SVIVEATTRLSTLLDLRYQKHYEAENGEVGGGSNCQGRRGADVRIPVPVGTIVLDANT
                     QELLADLTADGESCVIAKGGLGGRGNSRFATSTNRVPTQFEPGTPGEERLLRLDLKLL
                     ADVGLVGYPNAGKSTLIAAVSAARPKIADYPFTTLTPNLGVVRSTGEHSFVIADIPGL
                     IEGAHEGKGLGFQFLRHIERTSLLIHVIDISEWATEEPVASLKVMRHELSAYDEALAA
                     RPFAVVGTKLDIKGEGERLEQLRKYCQRRKIPFFAISAATREGLDECILYMGQQVELL
                     RKTPCETNS"
     gene            complement(47052..47315)
                     /gene="rpmA"
                     /locus_tag="PK063_05735"
     CDS             complement(47052..47315)
                     /gene="rpmA"
                     /locus_tag="PK063_05735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014959899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HMZ96580.1"
                     /translation="MATNKGGGSTRNGRDSNPQYLGVKAYGGETIKAGSIIVRQRGTK
                     FFPGLNVGLGRDHTLYAYVSGVVKFEGGRGRQKVSVYPVTAKA"
     gene            complement(47337..47651)
                     /gene="rplU"
                     /locus_tag="PK063_05740"
     CDS             complement(47337..47651)
                     /gene="rplU"
                     /locus_tag="PK063_05740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HMZ96581.1"
                     /translation="MYAIIETGGKQYRVETGTVLQVESLPGDVGHSVQIDKVRLLNGD
                     SGLVIGQPVVAGARVTAEIIRQGRTRSITVFKKQRRKNYRRTRGHRQGFTQLRVTEIA
                     SK"
     gene            47862..48776
                     /locus_tag="PK063_05745"
     CDS             47862..48776
                     /locus_tag="PK063_05745"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transaminase"
                     /protein_id="HMZ96582.1"
                     /translation="MLQTSEKIWMDGKFVAWADAQVHVLTHSLHYGLAAFEGIRCYKG
                     TSGSAIFRLPEHVDRLFESAHIGLIEIPYDRKQMTDAIIETVRVNRLEACYIRPLVYI
                     GYGAMGLYPGENPIKVSIAAWKWGTYLGDEALQKGIRARVSSFTRHHVNVSMTRGKIS
                     GYYVNSILAKREVKADGYDEAIMLDPEGYVAEGTGENVFIVRRGVLKTTPLTSILEGI
                     TRNSIIQLAKERNIPVVEERFTRDEMYVAEEVFVTGTAAELTPVTEIDQRRIGTGKPG
                     TITQTLQKAFFDVVRGTDAAHSQWLTPV"
     gene            complement(49017..49370)
                     /gene="secG"
                     /locus_tag="PK063_05750"
     CDS             complement(49017..49370)
                     /gene="secG"
                     /locus_tag="PK063_05750"
                     /inference="COORDINATES: protein motif:HMM:TIGR00810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HMZ96583.1"
                     /translation="MYTLLIIIHVIVCLLMIGAILLQSGKGAEIGAAFGGSSQTVFGS
                     RGPANFLSKFTVITAFVFMFTSLSLAILAKDRNFSSTVIDLNKKPAATTPSTTPAETA
                     TPPAKDSHSSTDSSH"
     gene            complement(49381..50160)
                     /gene="tpiA"
                     /locus_tag="PK063_05755"
     CDS             complement(49381..50160)
                     /gene="tpiA"
                     /locus_tag="PK063_05755"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HMZ96584.1"
                     /translation="MRTRFLIGNWKMNKTATEAGAFVRRLTQELPRSEGIQVGFAPPF
                     TALHAAHEALGSSPDFLLGAQDLYWEDKGAFTGEVSGAMLKDLGCQFVLVGHSERRQY
                     FGEQDSWTNKKVLAALRNGIQPVLCVGETLHDRDTNQTDQVIQRQVRAGLAGIEGQHL
                     ESMVIAYEPVWAIGTGRAASPEQAVPVHRLIRQTINELSGAEAGARVRILYGGSVTPH
                     NIAEFLASEEIDGALVGGACLDPVSFATLAKVAIGSKPTTA"
     gene            complement(50196..51395)
                     /locus_tag="PK063_05760"
     CDS             complement(50196..51395)
                     /locus_tag="PK063_05760"
                     /EC_number="2.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HMZ96585.1"
                     /translation="MNIRKRIIEDLQLRGKRVIIRADYNVPLDDSLQITDDTRIRSTL
                     PTINRAVDEGAKVILCSHLGRPKGKFDPKFSLAPVAKRLQRLLGKEVIFAPDCIGSAV
                     EGLVAKMQPGDVMLLENLRFHPEEEKNDEGFSKALAALADVYINDAFGAAHRAHASTV
                     GITKYIPEAAAGYLLKKEIEYLEGAVENPVRPFVAILGGAKVSGKIGVIENLGKKVDK
                     VIIGGGMAFTFLKAMGLEIGQSLVENDMLDFAKGVQDHAFASGVKFYLPVDCVVAAGR
                     EPGAETKIVPVQEIPKGWYGLDIGPASVKLFSEAVQDAKTILWNGPMGMFEVDAFARG
                     TLAMAHSVANAYALTIVGGGETALAIHRAGESESISFISTGGGAALELLEGKTLPGLA
                     ALPNRAA"
     gene            complement(51492..52499)
                     /gene="gap"
                     /locus_tag="PK063_05765"
     CDS             complement(51492..52499)
                     /gene="gap"
                     /locus_tag="PK063_05765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0019682 - glyceraldehyde-3-phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HMZ96586.1"
                     /translation="MTTRIGINGFGRIGRNVLRASLGDPSLEFVAINDLTDAKTLAYL
                     LKYDSVHGTLDASVEAKDDQLIIDGRAIKVLAVRDPKELPWKALGVDIVVESTGHFTD
                     REGAGKHLSAGAKTVIISAPAKDPDATVVLGVNEQVFDAKAHHIVSNASCTTNCLAPV
                     AKVLLENFGIKHGVMTTIHSYTNDQQLLDLPHKDLRRARAAGMSMIPTSTGAAKALHL
                     VIPQLKGKLDGLAIRVPTPNVSLVDLTVETEKDCDVAGVNAAFKKAAEGPMKNVLAYS
                     EAPIVSIDLKDDAHSAIVDAPLTAVIDKRLVKVTAWYDNEWGYSCRVRDLIKYIVAKS
                     A"
     gene            52715..55147
                     /locus_tag="PK063_05770"
     CDS             52715..55147
                     /locus_tag="PK063_05770"
                     /inference="COORDINATES: protein motif:HMM:TIGR01069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HMZ96587.1"
                     /translation="MQSEKLQFEACKVLEWAKLLDLLAGYAQSEVGAEQCRSMELERD
                     VAQARLRQEETSDMLRLRASVDPFPVLRFPDVTEWLKRVVKGACLEAHELRDIALVLE
                     LVVDVQRYLLRHQSDAPTVGAMAEQLGPVMEYRRLTVALNGAIDPDGSIRESASPELH
                     RLIQRANDFKQQMRHRLEQILHSRRYEEVLQERYFAQREGRYVVPIKAEMQGRMPGIV
                     HDVSSSGATLFLEPRELVDLNNSIKVVDLDIEREVRRILRELSALVAPHQPALAGSVT
                     LLGRLDAISAKAGLSQRLQGSPPRLNDQGRILLTQARHPFLVVSKDQVVSNDLAFDET
                     VRVLIISGPNTGGKTVILKLLGLFSLMVRCGLHLPCAPESEMAIFPSVYADIGDAQDL
                     ARDLSSFSAHITQMVQLLNEVSDGAGSEHDREPVPPGRALVLLDEPVTSTDPAEGAAL
                     ASALLCRLAAAGVKVVATTHYSLLKGLAQDRPGFANASVEFNLDTLSPTYRLIQGQPG
                     GSAAIEIAGRLGMDQSLLEDARARLQGDNRLLETLLSDLQDKQRRLNDDLVAATAARQ
                     GAEQASREAQELLTFLQESERDERQGLKKKLSQEFQRARAAVQATMDDLKRDQKLLKA
                     KEAKARLVELEESVRREAGDSEEPIPIDQLTIGDAVEVIGLGMTGTLLENPQGKKRVR
                     LKVGEGEILANVASLAGVSKARQPQAPAAVKTSVVSPRRTSQTLAPEDIQETLDVRGQ
                     AADDALDVVVAGLDRAILGGSPFVRIIHGHGTGRLRSALRDYLKDSPYVVAFRGGDRA
                     EGGDGVTIVQLR"
     gene            55256..57397
                     /locus_tag="PK063_05775"
     CDS             55256..57397
                     /locus_tag="PK063_05775"
                     /EC_number="4.6.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF017076.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_function: GO:0016849 - phosphorus-oxygen lyase activity
                     [Evidence IEA];
                     GO_function: GO:0032555 - purine ribonucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate/guanylate cyclase domain-containing
                     protein"
                     /protein_id="HMZ96588.1"
                     /translation="MPFSPRTKKILSAIAVGVAVYALVTGLRMTRWFEVVELKAFDHL
                     VRRYADPAKADSSLVLLAIDESSLEAFGRWPWPRDRYGYVVRYLKRAGAKAVVFDVMF
                     FEPDDNAEEFDQSFADDVKAAGNVFLPMLFQSEAAPVPAGLQDHATVKAERSDSGPVQ
                     AAAHPGVKLPIPVLAQQARGLGVINLSADADGPTRRLPLLGQVQGNLVPHLSLAVARY
                     VLGGSELAMRDDRLQIGDSSVPLDADGNLLIEWHGSLEQTYHARRYSIGRVLQAFAQQ
                     EKGERPDLDASLFKDKIVFIAGTAAGLYDLRVTPFSSATPGVLIHMAALDNLLHGQGL
                     QAAPSWFSLSILLLLCLVSAGAFMLFPSYPVKFGVTIGLALAYYGLVAHAFAGHERWL
                     DLVFPEVALALTFGTAATVEYVTEGKQRRLMRAAFDKYMSSEVVEEIMRNPAAIKLGG
                     EKKEISILFSDIAGFTTISEKMSPEDLVALLNRYLSAMTTIIKTTHRGNVNKYLGDGI
                     MALFGAPLNDPQHASLACYAALDCQVELARLRQVWKQEGLPEIGARIGINSGACIVGN
                     MGSEERMEYTVTGDSVNLASRLEGASKYYDTLILIGQRTAELAKNDVEVREIDLLRVK
                     GKKDPVVVFELLARKGQVEEKKRRVIDVYLEGLAAYKVRNFSIACAKFSEAVTLDPSD
                     GPSRVYLDRATNYCQTPPSADWDGVYEMTSK"
     gene            57424..57936
                     /locus_tag="PK063_05780"
     CDS             57424..57936
                     /locus_tag="PK063_05780"
                     /inference="COORDINATES: protein motif:HMM:NF019844.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HMZ96589.1"
                     /translation="MISPRVLRVVLIVLWIGLLVWSGEGRAETVYVQAKTAQLRAGKT
                     SLDAVVGNVKFGDALEVVGRDGSWVEVKTSAGAKGWIFANKTSSSKPSGTNDTLAKLG
                     QSMRGSDASATTASAGARGLDKASEGYANRAGVSARDRDAVDRMTAYQIPDQEVEEFL
                     REGGLGEYAK"
     gene            57926..58792
                     /locus_tag="PK063_05785"
     CDS             57926..58792
                     /locus_tag="PK063_05785"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: protein motif:HMM:NF013594.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metalloprotease"
                     /protein_id="HMZ96590.1"
                     /translation="MRSNHGLTATIIALSLMVAGCAEVQRASEDIARQSGNPRLAGAI
                     HGVGNVVGSLFPIGYEEESSIGQAMALQVVARYGGVVDQPELVRYVNLVGRAVANTSD
                     RPDIPYRVAILEHESINAFAAPAGYIFVTRGLLKQVRNEAELAAVLGHEIAHVSQKHI
                     LDVIQRSKRLAGVTEAGLSYATSNPAAFKTVIDGAVKKLLDEGLDQDKETEADTIGEV
                     FATRVGYDAEAYVNLLTRLRDLKGDDRALFKTHPNFSARIEAVQKTIQSKHLVATGVL
                     LPERFARMTKRV"
BASE COUNT        11665 a        16082 c        18234 g        12924 t
ORIGIN      
        1 gccgtgcgcg aagctccttg gttactacaa gaagcagcgg tggttgaatg gttgaagcgt
       61 atcgccagca ccctggcagg gtcttcatcc catccagtcg cggctgtaaa gaagttctgg
      121 aaagaaatca caaacgcagt cgcagaggcg gagacaattt acaccggttc attgcgtcga
      181 ttattcggag aacttcttga ggcggcggcg atcagtatga agcgtggttc tccaagacgc
      241 gcccctcttg tagcagtcag cgccctgctg aatgatccta gctcctggat gcagcccgca
      301 cgtctttatt cgctgtaccg cgcttggacg cgagaatcct tagccacagc agaacacgcg
      361 aaagtctctc cgtagccgta ttcgccgagg actttgacgt ccgaggaacc atgacactca
      421 gtatcatcat tccgtgccgt aatgctgctc gcacaatcga ggagacgctg caggcgcttg
      481 ctgaccagaa gtggccggca gcgtgggaag tcattgtcgc ggataatggt tccaccgaca
      541 acctggcgag agtagtcgcg aagtacacct tgcggatacc gcatcttcgt cttgttgacg
      601 cctctgcacg gcggggcgct tcctacgcaa gaaatatagg ggttaacgca gcgaccgggg
      661 agtatatttt gttttgtgat gcggatgatg ttccggcggc aggttgggcg atcgccatgg
      721 aaaaagccgt acgcatgcac ggatttgtgg cctctcgttt ggagtttgaa aagctcaaca
      781 gtccggttgt tcggtcggcg cgtggctgca cgcagatcgt tgggctccaa cagtttcgat
      841 ttttgccatt tccgcacgca ggatcgggaa cacttggtat cacacgtgcc ctgcatgatg
      901 cagtggccgg atttgatgaa acaattccga tttgtgaaga tatcgactac tgtatgcgag
      961 tgcagcaaca agggataaaa ctcgaatttg ttccggacgc ggtattgcat tgccggcttc
     1021 gggccagcaa aaaaggcgtc tatgcccagg cctcgcagta tgcggaatat gaagtctact
     1081 tatataagaa gtatggggct ggtcatctgt gggaatggtg gcgttggcgc aagtacatac
     1141 aggcgtggcg taatctgctc ggacgtatgt cggaactgct tcgtactccg gaagggaaga
     1201 ccctattcgc ctggcgtctt ggacgtttga tgggcctgct aaagggaagc ctccgattct
     1261 gggccccgcc agtgatggtg gaatgacgcg ggaatcgttt ccatgagtct tcaatccttt
     1321 ctgtcaacct cagtgcggaa ggtgttggga agtctaaccc atgtcgtcac gcccagcgca
     1381 gtgcttgctc tgacctttga tgacggtccg gatcccgaaa acacccccaa agtcttggct
     1441 cttcttgaaa agtatcaggc gcgtgggacg ttttttgtgg tggggcaagc tgctgcagtt
     1501 cagccggccc ttgttcagcg gatagctgcg ggagggcatg ctatcggtat tcactcctgg
     1561 gatcaccgcg catttcccgg tttaaccagc cgggagcgtc gccggcaaat ccgtgaatgc
     1621 gagcgcgcat tgcggcccta tgtcagccca ttgtttcgtc cgccttatgg agagcagacc
     1681 gtcatgtcac gcctggaagc gttcatgatg gggtacgagg tcgtcggatg gaatctgaac
     1741 agcggagatt ggtatgaatc ccagtcctcg gtaatgggca aatatctgtt ggaaatggtg
     1801 tcgccgggcg ggatcgtcct cttccacgat actctgtacg ataaaggtac gcctgctcat
     1861 gggaccgatt ccgaacatac atcgtggcca gaccgtcaag ccatgctcga cgccttggag
     1921 acgatgcttg atcgattgag cggaagctat cggtttgtca cggtgccgga gctgcttcaa
     1981 gccggacggc caagacgctc cttttggttt aagccatcgc tggcaacggc ctgaatgcga
     2041 agacaatgac gggagctcaa gaaagaggca gaggatgagc agtgtggcgg tggtggtgcc
     2101 gggatataac agggcggaat ttaccgaaga tgaagagatt tccttccggc atttagagca
     2161 ttacctcggg cgctatgaca aattcctcgt ggttcctcaa agccttgcca ttgaacggcc
     2221 tgggtttcac attcaacgat ttcccgattc ctattttgga agtgccatcg cgaatgcgag
     2281 attgatgctc tccccaacgt tttatggcgc atttcaatcg taccgatatg tgttgatcta
     2341 tcagctcgac gcgttggtat tttccgatcg gttgatggag tggtgcgcaa gtgattggga
     2401 ctacgtcggt gccccttggc tgaagtgtgc cgatagtccg tgggtcggcg cgtctcgtgt
     2461 cggcaacggc ggtttctctc tccgaaaggt gtccagtttt ttgcgtgtcc tgtcctcgga
     2521 cgcctattgg gtggatcctg aggtgtattg gcaacgtatt actaccggac agtcctggta
     2581 cgtgaaatct gtcaatttgc cgagaaaatg gtataagcaa atcaagcgat tcaataacgt
     2641 gaagcgggaa ttggaacgtt ggcatctgcg tcctgacggg accaaaaacg aagatcattt
     2701 ttgggccgac gaagcggtgc gctatgatgc ccaattcaag gtggcgccgt ttcatgtcgg
     2761 attggatttt gcctttgaag tagtcccacg gcattgtttc gagctgaatc agaatcgatt
     2821 gcccttcggt tgtcatgcat ggccacgcta tgatcgctcc ttttgggagc catatctcat
     2881 caagccttga tggaatcgtc atacttatga atgagtcgga attgcagcag gcgtcaccgt
     2941 tgacggctgg cactctcgcg ccggcggttc gaacgccgac ggtcaaaatt cgccccagtc
     3001 gaggtctgtt tcatctagac ctgcagtctg tctggcagta tcgagaattg ctgctctttc
     3061 taatctggcg ggacacaaaa gtccgttaca aacaggcggt gatcggcgcg ggatgggcgg
     3121 tgttccagcc actcatttcc atgctgctgt tcactgtgct gttcagttac ctcgcgaagc
     3181 tgccgtctga tggcgtcccc tatccattat tcgcctatgc cggcctactt ccgtggaact
     3241 tcatcgctca ggcgacgagc cgcagcggca ccagtttagt gggagagtcg catttgatca
     3301 gcaaggtcta tttccctcgt ctcattattc cgctcgccgc cgcatctgca cccgccgttg
     3361 atctgctctg cgcgttgctg atgatgattc cgctcatgtt atggtttggc gtgaccccgg
     3421 gttggcagtt gctgttcttc cctgtttttg tgggaattgc cttgctcgcc gccctggctg
     3481 tgagtttctg gttttctgcg ttacatgtga aatttcgcga tgtcggacat atcatcccat
     3541 ttttcgtgca gttttggatg tttgcttcgc cagtcgtcta tcccgcgagt ctcattcctg
     3601 aaaaatggcg caccctctac agcctgaatc ccgcggtggg agtcgtagag ggttttcgat
     3661 ggagcttgct ggggcaacgt cctccctcac tcgaaacgat tctcccgagc gtaggcatcg
     3721 tcctggtttt gttcgtgagc gggatcgttt actttaaacg tatggaacgc actttcgcgg
     3781 acgtgatttg atggctgaga tcgcaatttc cgcacggcac gtgagcaaag aatatgtcat
     3841 cgcagagatc aatcatgaca ctttgcggga tcgcatcgct catggctgtc ggtctctcct
     3901 gggacgacgc gctgcgaaga gtgtaccccc aaaatccttc caggcattga acgatgtctc
     3961 attcaatgtc atggaagggg aggtcctcgg ggtaatcggg cataacgggg cagggaaaag
     4021 cacgctgctg aagattttgt cccgcattac cgaaccgacc ggtggagaag tggatctata
     4081 cgggcgcgtc acatcattac tggaggtggg caccggattt catgcagagc ttacgggccg
     4141 agaaaatgtg tacctcaatg ccgctatgct gggcatgcgc aaggtggaca tcaataagag
     4201 attcgaggcc attgtcgaat tctccgggac gcagcaattt atcgacacgc ctgtcaaacg
     4261 ctattcaagc ggtatgtatg tgcgactggc tttttcagtg gcagcgcatc ttgatccaga
     4321 gattctgatc gtcgatgaag tgctctccgt cggcgacggt gcttttcaga aaaagtgttt
     4381 ggggaaaatg gacgaggtac ggagagacgg acggacggtc attctcgtca gtcacgattt
     4441 gccggtagtg gcgagcctct gtcagcgggc tatcctgctg cggcatggcc gggtcgtggg
     4501 tgatggccaa ccgcaacaga tcattgagca atatatgagc gaggcattca caggtaccgg
     4561 agtctcgcta gccgatcgca ccgatcgtta caccaaaggc gaactgacgg tgcaggcgat
     4621 taccttcctg gacgacaaac ttaaccctct gcagccggca ttatcggggc aacatcttgt
     4681 cattcgcgtg cagtataagt gtcatgtccg gaaggcattt aaggatatgc gtgtcatggt
     4741 tgtcatcaat cgtgatgagc gcacgtcctg tattttttcg acggatcttg tgagtcatac
     4801 ccctctggat ttggagggca gcggctatgt ggacttccat gtgccgcatc tgccgttatg
     4861 cggcggccga tactttctcc atgccgcgat tgaaaacaat accatgacgc aggattgggt
     4921 tcagtatgca gctgagctgc aggtcttaga tggcgactat tacgggaccg gccgaatgta
     4981 tccgcatgac ggatggcggg gaaaaggcat gttcgtcgac cacagttggc gatttgaaag
     5041 aacctcctga ctagggccta gcgacgacct gaccctctct ttttccctcg tgccatccgc
     5101 cacttccatc agttcatcgc gaaagtttcg gttttccccc ttagcgccag tctgtttctc
     5161 gatgaaacat tcctctctgg ggctacgttg ccgtcgacca atccatggtc ctgatccatt
     5221 catggcaggg ccgtgatagg gccgattgtc aggggtttac ctgatttgtt ctggggggta
     5281 tcttacgcat gttttagcct gtgaatcgcg aatcggtgtc gatgtgagtc tggtgggagc
     5341 gattcgagca tgttggttgc catctgcctg ctgactgccg gtgtctttgc cctggatgtc
     5401 gcgatgtcgc tagggcatgt catttggctg ttgtatgcgc ttccactctg gttgagcgtg
     5461 cgattgacct cgcccgcagc acccctgcgc tatgcctctc tatgtacgct tctgcttggg
     5521 acggctgtgt gggttgcgcc tcctgggatc gagctcacga ctgcggtcat gaatcgtaca
     5581 ttgggactcg cattgctgtg gggcatggcg gtcctactct cacaacggcg tgagtcagag
     5641 accgcgcttc gctcagccaa tagccgattg gagcagcgtg tcgctgaaca gacgcaagat
     5701 ctgagtgccg ccaatgatcg actgtctgtg cagttggccg aacagcggca ggtcgaagtg
     5761 gcattacggg agagccgtca acggtttgag ttggcagcgg aatgcgcaga tgtgggcgtg
     5821 tgggaatggg atttggtgac caagtcggcc tattactcgc ctcggtggaa aactcagctt
     5881 ggttgcacgg aatccgacat tggtcccacg gtcgccgact gggagtcgcg tctgcatccg
     5941 gatgagcggg cacaggttct tgcgacggtc acgctgtttc agcagggtta taccaagcag
     6001 tatcgcttgg accaccgcct tcgacaccag gacgggtcat atcgatggat ggcggcattg
     6061 ggcgcgggcg tttatgacga gcaggggtgc atgatccgca tgacgggcat ccacctggat
     6121 attacggtga gaaaacaagc tgaggaggcc cgaagggaga gcgaggagcg ctaccgggag
     6181 ttagtggaac aggccgggga tattatttat cgcaccgatg ctgccggacg attcacgtac
     6241 tgcaacccga cctcattgcg gattctcggc tatttcccgg aggaactgct cggccgccat
     6301 tacctggaca ttgttgagcc gcagagtcgt gcgcaggcag agcgttttta cggacggcag
     6361 tttatccgca aaacgctccg gaccgtgtac gagttgccgg tggtgaccaa agatggtcgg
     6421 gaagtgtggc tggggcagca cacacaactg ttgatggagg gaaatactgt ccacggcttc
     6481 caggtggtgg cgcgggaagt caccgagcga aagcgagtgg agcaggcgtt gcgggaaagc
     6541 gaggagcgtt tttccaaggc gtttcatagc agcccggcag ggatggccat cagccggctt
     6601 aaagacggac gggtacttga tgtcaacgag gcgttcgtgc gtgtctcggg attttctcga
     6661 gaagagctga tcggcatgtc gtcactcgac atcggcatct ggatcaatcc ggacgaccga
     6721 cnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nctgatcggc atgtcgtcac
     6841 tcgacatcgg catctggatc aatccggacg accgacggca cttggcagag gccttgcggc
     6901 gggatggttt tctccggcat ctggaaaaag agttccgtac gaaatccggc gaactccggc
     6961 acggtctctt caatgtggaa ccggtctgta tcggtcacga aaactgtgtg ctgacgctgg
     7021 tgctggacat caccaggcgc actgaggcag aagcggcatt gcgccgcagc caaacggtgc
     7081 tccaagccca ccagcatgcg ttgatgcgtc tcacaaaaag ccaacatatc ggctcggggg
     7141 actggccgtc cgcgctgaaa gaactgatgc agacttcggc ggaggccatg gctgtcgatc
     7201 gggccagtgt ctggttattg gatcgcaccg gggcggtatt ggagtgcgta gagctctatc
     7261 aacgaaacga ggcgcggcac tcgcgggggg cacgtctgga tgtggcgcag tatccgcgct
     7321 actttgccga gttgctggag gagcaagtcg ttgatgcgca tgatgtggcc agcgatcctc
     7381 ggactgctga attgctgcag ccctatcttc aaaccatggg gattgcctcg ttgttggacg
     7441 tgccgatttt cttcggtgga cgcctggccg gggttgtgtg ccatgaacgt ctcggctcgg
     7501 cgcgaccgtg gagcaatgaa gatgcgcagt ttgccacgtc catcgggaat ttggtcacgc
     7561 tggcctacga gtcgaagcaa cggcgtgagg cagagagcgc cctcgttact gcgaaggagg
     7621 cggccgaatt tgccagtcgg gcgaagagcg actttctagc caccatgagc catgagatcc
     7681 ggacgcctat gaatgcgatc atcggcatgg ccgatctgct gtcggaaacg ccgctcagcg
     7741 aagaccaacg ggagtacgtc cagatttttc gggacgcggg gggaaacttg ctgagtttga
     7801 tcaacgatgt gctcgatctc tcgaagatcg aagccggtca tctggatttg gatctcacgg
     7861 acttcgatct cagtgacctg gtacagcgcg cagccgaatt ggtcgcagtg cgtgccagcg
     7921 aaaaaaatct tgagctggcc tatcagatcc aaccggatgt cccgacctca ctcgtagggg
     7981 atccgaatcg cctccgccag gtactgctga acctcttggg caatgcgatc aagttcacag
     8041 atcagggaga agtcgtgttg cgcgtcgaat gcgacccgca cgcagagggg cccggcagtc
     8101 tgttgttcac cgttcgggat accggcattg gaattcctcg agacaagttg gccgtcatct
     8161 ttgaacggtt cacccaggtg gattcttcga tgacgcggcc gtatagcggc actggtctcg
     8221 gtctcacgat ttcacggcgc ctcgtggagc gaatgggcgg cagaatgtgg gtggagagtg
     8281 aacccggccg cggcagcacc ttcagcttta cggccaagtt tgctgcgcac gcgcaaccgg
     8341 cctcaccggt ccccacggca caatgggagc aacttgcggg gttgcggacc ttaatcatcg
     8401 acgataatgc caccaatcgg ctgattgtgc gggaaacctt gagtagctgg gggatccctt
     8461 cggcggaagc ggccggggga gacgaggcat tgctggaatt gcgccgggca ctcacggccg
     8521 gcatgcctta ccgtttggca attctcgacg tgcgcatgcc gaaactcagt ggatggcagg
     8581 tggccgaaac catcgcacgc tcgcccggtc tggccggcct atcaattatc atgctgacat
     8641 cagaacggcg cgccggtgac caggcccgag cccgtgaaca tggagtcgtg cggtacctca
     8701 cgaagccttt tcgacgctcc gatctgttca acgcgatgat ggccgtgttg ggcaagacag
     8761 cgccagccgg gaatcctgaa tccgaagctc cttctcagcc gaaattcgct ggagatgacc
     8821 agtcaggcct gaagattctc ttggcggaag atttcctcga caaccgccgc atgatggagt
     8881 tttatttcaa ggcaacgccg catcgggtgg cgacggcggc caatggtcag atcgcgctcg
     8941 agatgttcat gcacggatcg tatgatctgg tcctgatgga tattcagatg cctgtgatgg
     9001 acgggtatgc cgcgacgagg gccatccgcg catgggaaaa agaccaacgc cgcagatcca
     9061 cgccgatcct ggcattgacg gccaatgcgc tgcagagtga ggtgcagcgg agtcttgatg
     9121 cgggatgtac ggcgcacctc acgaaaccca ttcgtaaggc tcagcttcta gaggcgattc
     9181 aactctattt ccagacagcc tcctcccagc cgccagttcc cgcataccac gaagaacctg
     9241 ccgtgcttca tgtcaacgtc gagctggaag ccctcatgcc tgggtttcta gagcatcggc
     9301 gccaggactt gatccagatg acggcggcat tggatcgtga ggattttgag gtgatgcggg
     9361 aaatcggcca cggtctcaag ggagccggcg gaacatatgg gcttgaagcg attacagcgt
     9421 atggacggtc cttggaaacg gcggcctcga gaaaagatgg tcccgcgtta cgcgaaatcc
     9481 tggaacggct ccgccggttt ctggatcggt tgcaactgat ctacgtgtaa aggatagacg
     9541 gtatgcgcgt attgctggtt gaagatcatc ccgatgtgcg actcctgttc gagcaggtca
     9601 tcggggcccg aggacatgag gtgacggcct gcgctgatgg cgaatcggca tgggaggcct
     9661 acggcaagcg gtcatatgaa ctcgtgctgc tcgattggga attgcgtggt ggaggaatgg
     9721 acggattgca gctctgccgg aggattcgct ccggtcccgg cggagatcgc tgtgtcatcg
     9781 tcatgatcac cggacacgat tccccggaat ccttgcgtgc ggcgctgcag gccggcgtca
     9841 acgactattt agccaagccc gttggtgtcg agttcttacg attgcgattg acgattgccg
     9901 aacagtgggt cgaaagtgtg cggcgccgct ttgcagctga agatcaggct caggcgctgc
     9961 aatcgcaact ggcggaccac ggcaagtttc atgatctgat cggccgaagt ccgtctatgg
    10021 tggtcttgta cgaggagatt caacaaattg cggcagtgga tgcgaccgtg ttgatcgaag
    10081 gcgaaaccgg cacgggcaag gaactggtgg cccgggcgat ccatctgtcc agccggcgcg
    10141 cgccgcacac atttcttgcc gtcaattgcg cggggttcac cgactcgatt ttgggcagtc
    10201 agttattcgg tcacaaaaag ggcgcattta ccggcgctat cgacaaccag gaaggtgtct
    10261 ttgaggccgc gcaagggggc accatttttc tggacgagat cggcgatatt tcccctgcag
    10321 ttcagacgag cctgctgcgc gtgcttcagg agcgggaagt cacgagactg ggagaatcca
    10381 agcctcgaaa agtcgatgtc cgtgtcgtgg tcgcgaccca tcacaacctt gtggaagacg
    10441 tcgagaaagg cacgttccgg agggatctgc tctatcgcat caaggtggct cgccttcagc
    10501 tgagtccgct ccgtgaacgg ccgacggata ttccgctctt ggtccatgcg tttcttggtc
    10561 aatttcgttc ggtgatggaa aaaccggtgc tgcatgtgag tccagaggcg ctgcaggtct
    10621 taacgagcta ttcgtggccc gggaatgtgc gggagttgaa gagcgccgtc gagtcggcct
    10681 tgattcattg caaagggacc gtcgtgcgtc cggaagatct ccccccggag atccggagcc
    10741 cgcaaccaca ggccacctat gttccgctcc agcgacaaga cgaacgaacc cgcatgctgg
    10801 gagccttgca gcagacgggc ggcaatcgtt cagaggcggc tcggttactg gggatgagcc
    10861 ggagaacctt ttatcgtcgc ctggctgaat acgatgtggc tgcctcggcg gagcccggcg
    10921 cagagtcctt cctgtgaact ggtgagcgta tgcgcacgcg cgcttcgttg ctctcaagtt
    10981 gccctcaatt ggacgtattt cttaataacg tcatgcaccg ttcacgctga tctcctttcg
    11041 gtttccctat tgcaagtctg cgtgttccgc acatcactgt gcatagagtc acatgacaca
    11101 cgtgtgacac agcacagtgt gccatctcat tgacgcatgc gggtgttcac cgacgtggtt
    11161 tcgggcctaa gccccagtat ttcgtggagc ttgttgttcc ttcatcgatg gcacgatcct
    11221 tgatacatga tctccacgaa cagcgtagtg gagagaaatg gtggaacagc aagggccgag
    11281 tcagaaagag ggcagcatgg aggttgaagg atttctcctg tcgaacgata tggaccagga
    11341 ggtcttggtg accattccgc cttcatctgt cggcccattc gatcaaccag ccgtcaaaga
    11401 gcgtattgat ggatattgga tcgagatgtc tcgattgccg aacaggagat ggtctgaccg
    11461 gacgcgtgcg gtcggagccg tgctgacgta cttgcaaggc ttgtcggcaa tttcgtcagg
    11521 gtttgctacc cacacgagat gacgagaagc tgcaaccaga accaaaggag tacagaccat
    11581 gtggaatgac cagaatctat tgcggagtgc ccgggaagac aatgcgcggg atggagcagc
    11641 cggactgagt gtggtgccgg gcgtgagtct cacggcgaaa cgtcgccctg aagatttgac
    11701 cccgcgcgaa caggaaattc tgcagctggt ctgggcggga ttgaccaatc gcacgattgc
    11761 ggaacaattg cacatcagta tcaagacggc cgaggcgcat cgggccaata tgatgaaaaa
    11821 actccgggtc tccaatattg cgcagctatt gaaaacggcg ctggaagagg ggctgctcgc
    11881 cacccacgcg ggctgaaggg attcgcggcg gcctgcactc tcgggggaag tcccacttcc
    11941 ggcagtgcat cggctccccg cgagtccgcc ccctcacagc acaaatgagg ctcgcaccgg
    12001 cgacggcgtt tgcagtagaa tgccgcaccg tcgctggagc gagccgtggt cgaacaacgc
    12061 atcgaagaaa ttacccgcgc caatctcgcc ttttatgccg cctttgaaag tctggatatg
    12121 ctccagatgg acaaggtgtg ggcacatctc gaatacgtca cctgcattca ccccggctgg
    12181 acccttcgga gcgactggcc tgccgtacgc gattcctggg tgttgatctt caacaatacc
    12241 ttctccatga aattcgaact atccgacgtg caggtacagg tggcgggcga tctgggatgg
    12301 gtgatctgca ccgaacacct cacgagcagg caggacgacc agccggtgga aacgcgcgta
    12361 ttagccacca atctctttga acggatcggt gatgagtggt tgatgatcca tcaccacggc
    12421 agccctgtca tggggtaggg ggcaatgagt gcggaggccg gatcctgtct actggccagg
    12481 cacctctgcc cgcacggggg ctacagcggt ggatgccgat gctcggcgtg tgaatggtaa
    12541 acgttcctgc atgacaccct tatctctcgc cgtcagatgg acaggcttct gcgcccttct
    12601 gttgtccgga tgtaccacgg tggctcagat tacaaccctg tcggatgagt cctgtcggca
    12661 aactgtgcgc ggtcaactgg aatccattct cgttgaagag ggagaacgac ccgagatggc
    12721 aactcgtctc gcggtcaaca ccaccgtggt cttggcaacc ggctctctag ggcctcgccc
    12781 gttcggagtc tcgtcgccct ctggcaccga ttacagtttc tttgtccagc gtaagggtga
    12841 aagctgcctg ctgcgtctgt atggacgtca aaagggattc acacgctaca ccaacaatct
    12901 cacctatatt tcgactcgtc ctctggaagg ttgtgcctgc gccgaatgac cggggctctg
    12961 actgtggtct tcttcctctc gtccatctcc tgcttctgaa ctgaatcctt gacccggtgt
    13021 gtcatggggg ctggcgcttc cggcgagcgg cagcgcggtg tcctattctg tctcgtcacc
    13081 tgtctcatcc cgccaatgtg gcacagctct gtgaatcatg acacagccag tgatgaccct
    13141 cctttcaaaa gataatttcg caagtcattg tttaatcagc aatggcagcc gcattgtggg
    13201 catggcacgg gccttgatgt agtgctcggt agatgtcgta aggcgaacac cttggggagt
    13261 tcaagggagg agggaagcaa tggaagtgaa agagcgtcca cgggtgagcc cattgtgcag
    13321 gaatcacaag gaggaacgat ccatgatggt gaaagggttt ttgctgaaag atcgggaaga
    13381 gcaggaatac ttgttggcca ttcaaccggc gacgcatggg atgttcgagc ggctcattgt
    13441 acgccagaag attgatggat gctgggtcga actcaatggc aatgcgcagg ggacctggca
    13501 gccgcgcacg caggccatca cggccgtgtt ggggtacctt caacgcctgt gggatacgtc
    13561 gaaaccggtc gcagctcgcg agaactaacc cactgatagc tcgtcaccat cagtgccggt
    13621 gagagacatt gaaggaggag gaccatgcag gccgaaaagc aagacagagg tggggacatg
    13681 atgagcggat cgtccatgaa gagccgcgag atgtctgacg atcctgaagc agctgccttg
    13741 aagcgcaagc ccgaagatct gacgcctcgc gagttggaaa ttctccgttt gatctgggat
    13801 ggtcacacca atcgcagcat tgcggagctg ctgaacatca gcatgaagac cgccgatacc
    13861 catcgggcca atatgatgaa gaaactgcgg gcgtctaata cggctcagtt gctgaaggcg
    13921 gcaatagaag ggaaattact gcacatccac gagggggccc ggcgttccga cggcgcgaag
    13981 tgattactca tgcctatccg caagcgtcgc cggcttcgcc tggtgaggcg acgcgggaag
    14041 gcacttcgag agtcagtgca acctgttcac aatccaggga tggggtgggg aatatctttg
    14101 gtgccgagtg tctgaagcca ctcacctgcg atgacatcac gttcttccat cgtcatgccg
    14161 gcatacttgc ggaacatctg ggggccacgt ctccgtcgcc aggtcagaaa tcccaggaag
    14221 tgatccttgc agatagaacg ggtgcctgcc ggcgcataca ctctcgcctg acaaccatcg
    14281 attaagcaac tctgtccgct catctgtgcc tcccaatcat tctcgggaag tatgccggag
    14341 atgcccccgc aaatgcaatg cagcgtccgg cgttcgagaa ggctcttgcc aggcgtcggg
    14401 aagatggcgc gaaggctcga tgccgtaccc gatgcctgcc ccatcagcgg gaatttcgct
    14461 tgcaatcctg ccgagtcgcc aggtaccgta ccccgttctc cagtgagatg cgggctcgag
    14521 tgcgcgagta tacccatgat catgcaggtc atatcggtgg tgggagccct gatggtgctc
    14581 atcgcctatg gcctcattca agccggtacc tggcgcgaat tggacgcagg ctatttggcc
    14641 ttgaacatta tcggctcact gctcctgggg atcgtagcaa ttgaagatcg acgagtgggg
    14701 ttcgtcctgc tggaattcgc gtgggcggga attgcgctgg tcggagtggc ccggtcgcta
    14761 cgagccaggc gcgccgcacg cggcctctga tcgtagatga catcatacac atcagacagt
    14821 cttgtaacga aggagtaagg cgttatggca gggttgttgt cggcggatga cgtatttgaa
    14881 caggcgaaga atgcggcggt aggagcgacc aatgcggacg aaaaggcgct ccagatcgat
    14941 tatgaagcct tgcagctcaa gttccgcgcc gcccttggtg atcgcaaagt ggcgcgatgc
    15001 catatcaaca agtttttgcc ggaaggttat gaagatcagg gccggttcaa tctcatcctg
    15061 ttgacggcgg gcaatgtgat ttttgacatc gtgatcggcg attcctattt ccgctacgat
    15121 gtcgtgtccg tcagccagtt ggacaaggtg caggtcatcg acgccatgtg ggacaaccgg
    15181 gagaagcgcc gtgaggaacc cttcttgagc ctccggctga tgcatgccga agaaacgcat
    15241 ctgttgttgg cgctggacga tgaagagcgg aagagcctgc ttggattcgc gtcagccgtg
    15301 tcggccgtgc gcaatcccga gaagtaaatc accggggcca tctcgcaaaa cggggaccag
    15361 cggtcttagt gtatgagagt cctgcaggat ggtcaaaatg gccgtcctgc aaggccgcag
    15421 caagtgaagt gccgaggcgt cccctcgggg acgttgaggc tctgagcgat acgggaacgc
    15481 cgcgggcgcg tgttttcaac atcctgcttc agggccgctg gtaaaacgga agggtatgga
    15541 cggtggcctg atggcgcgtc cctgccactt ccaccgtcag ctcggtgttg ggcgctgaga
    15601 agtcgcgtag cggaaagcca aatgccagga cggcatggcg ttgtggcgac aagacggcgc
    15661 tgctgatcca tcctacttcc cgatctccgc tgaatagctt tgatccatgc gccggtaccg
    15721 tctgatcctg gatcagtaag ccgactagat gccgccgaac attgccatat gtgtccatgc
    15781 gcgccacgac ttcctgcccc gggtagcaac cttttgagag gctgaaggcc tttccttcca
    15841 aattggcttc cggcgggaca atttcttcat tgagatcagg cccggccttg gccagacccg
    15901 cttcgatccg caacagttcg cgtgcgtggg agccgacggg tgtggcgccg aacggagcgc
    15961 cagcagtcat gagttggttc catgcggcgg ttagtccgtc agcaggcata agaatttcga
    16021 gatcctgttc gcccgtttct tccgtgcgca tgatcagtgc tggttggccg ccgactgtgg
    16081 tctggatggt ctgcagaagc tgcaagcgct cgacctccac gccaaatgcc gccgacacga
    16141 cctctgcgga tttcggtccg ctcaccagca gcaaccccca gctttccgcg caattctcca
    16201 tcttggcttt ggtgccgtag aggagaaact tgcgtaacgc ctggaaagtg gcttcaccga
    16261 cttccccgac atcttcgatc cacacggcgt cgctctggac gtacacccgg aaataaccga
    16321 gcattttccc cttatgggtg agnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16441 nntcaacgag atctttggtg cgcgcagaaa attcgttccg ggacacgact ttggtcacgc
    16501 cgagctcctt tgcgcgtcgc cacgtgtcga cttcttcatg attgacgaag gccaggacgg
    16561 gcagtgagcg cagggcagga ttgctctgaa tggtttccaa cgccttgaag gcatcgactg
    16621 ccaggtcgtt catgttcagg atgagcgcgg ccggctgtgt cgaggtcatt ttttcagcca
    16681 cctcatcctg attccggatt cgctccaagg tatacccctg cgggcgcaac gcgtctcgca
    16741 ccttcgtgta aaagaaaatg tcggtcacgg ccactacgat cgtggtgttc atcacatcct
    16801 gcttgggcta gttcagggag ctaatgaggc ggcccaaggc tttcttagcc aaggcataat
    16861 ccgggttgag agccagggct tgcttgtaac agtcgatggc ttcgctccac ttgccttggc
    16921 gttcgtacac gcggcccagg ttcaagtgag ggaatgccgg gctttcgtag cgcgtggcct
    16981 gcatggcctt ttgaaaccag ggaatcgcct cgtccaggtc ccccttttca atcaaatagg
    17041 cgccgatgtc gttgtaagga ttgccgaagt gtggatcgca tgcgatggcc ttatggcatt
    17101 cctcaatcgc ctcgtccagt ttgcccatga agctataagt ccagccgaga aaggtatagg
    17161 cttcggccgt ctgatgcgtg gcgagcgaga gtttgtacag actgaccgct tcctccagct
    17221 gccccttcat ctgtagttcg taggcttgct ggaacagttg ccaggcttcg cgcttgtctt
    17281 cctcgctgcc atcgccttgt atgagaaagt cttgtacatc catatgcggc ttctgaaaca
    17341 ggtttccggc tgcgttctcg ggcgctcact caactcgacg taccaacaca gtacgtctcc
    17401 tcgatttcgc ttcctgcggc cttgctggaa acccgtttga gaagccgcag gacagtatga
    17461 actaacgctt cttcagcttc tctcggatta actcggcgcc gtaccggcct gaaagtaaca
    17521 tcgacccaaa tgccgggccc atgcgtggcg tgccgaacac tgccgccacc gccagtccga
    17581 tcacaaagca attgggagaa acttctccgg ttcgatccat gacctcttct tccgatcgcg
    17641 agacccacat ggcgccattg ccgggaacct gttgatagag cccccgcttg tgcagcagat
    17701 tgaccaccac cgcgtcatgt ccggtggcgt cgacgacaat cttactctct aacgcgattg
    17761 gatcaacatg gataatatcg tgtccggcca tctcggcagt ggtgctattc accaccactc
    17821 cttcgagcac cccttcgcgg cgcagaatca ggtccacgac ccgcgtcagg ttcatgatct
    17881 tcgcgccggc gtcataggcg gccgcgatca acgcgccagt cgcatgcgga ggatcgacca
    17941 tgtacatgcc ggggcattct ttgatctgct tgcagggtac acccacctct ttgagaatct
    18001 tgtgcgccgg agcgcagatg gtagctttgt tcatcaagta gccgccggac cagaaccctc
    18061 cgcccaaggc caggctctgt tcgacgacca gggttttgac ccccatcctg gccagatcgt
    18121 gggcgcagat caagccagaa gggccggcac cgacgatgat gacgtcgctc tcgatcagtt
    18181 gatcgaactc gttgtaatat tcccgcgcaa tctgacgggt gatgtcgcgc tcgcgtagtg
    18241 gtgccggttt tggcttcccc atgctacttt tcctctcagc ggctgctgaa catgactccc
    18301 ggcttcgttc tcggctccat caaatcctca acgtacccct gagggtacgc ttccggtttg
    18361 agttcgcctg cggccttgcc ggatagccat gttgatcagc cttacaggta aatttcggaa
    18421 ccggcctttt tgaattcttc tgatttttcc ttcatgccga tctggatggc ctgctgctcc
    18481 tccagttgtt tctgcgccgc atagtcgcga acatcctgcg tgattttcat ggagcagaaa
    18541 tgcggcccgc acatgctgca gaaatgggcg accttcgccg cattgtccgg cagcgtggca
    18601 tcgtggtacg agcgggccgt ctccggatcg agcgcaaggt tgaactggtc ttcccaacgg
    18661 aattcaaacc gggccttcga cagggcgttg tcccgggctt gcgcgccggg atggcctttg
    18721 gcgaggtccg ccgcatgcgc ggcaatctta taggtgacga caccgacctt tacgtcttct
    18781 ttggtcggca atcccaaatg ttccttcggc gtcacatagc agagcatggc gcagccgtac
    18841 cacccgatca tcgcggcgcc gataccggag gtgatgtggt cgtaccccgg cgcgatatcg
    18901 gtggttagcg gcccgagtgt atagaagggc gcttcctggc attctttcag ctgcttctcc
    18961 atgttctctt gaatcatatg catcggcaca tggcccgggc cttcgatcat cacctgcaca
    19021 tcgtggttcc aggcgatctt ggtcagttcg ccaagggtct ccaattcggc gaactgtgct
    19081 tcgtcattgg catccgcgat ggagccggga cgcaacccgt cgccgaggct gaacgccacg
    19141 tcgtaggctt tcatgatctc gcagatttct tcgaagtgcg tataggcgaa gttctcctgg
    19201 tggtgcgaga ggcaccattt cgcatggatg gagccgccgc gagagacgat gccggtcatg
    19261 cgtttcgccg tcatcggcac gtagcgcagc aggactccgg cgtgaatggt gaaatagtcc
    19321 actccttgct cggcctgctc gatgagggta tcgcggaaaa tttcccaggt caggtcttcg
    19381 gccttcccgt tgaccttctc gagcgcctgg taaatcggca cggtcccgat cggcacgggc
    19441 gaattgcgga tgatccattc ccgcgtctcg tgaatgtttt tgccggtgga gaggtccatc
    19501 accgtgtcgg cgccccagcg gatcgaccag atcatcttct cgacttcttc ttcgatcgaa
    19561 gaggcgacgg cggagttgcc gatgttgctg ttgatcttca caaggaagtt ccggccgatg
    19621 atcatgggct cggattccgg gtgattgata ttgttgggaa tgatagcgcg gccacgggcg
    19681 acttcatccc gcacgaactc gggggtgatg aggctcggga ttcgagcgcc ccaggcttgg
    19741 cctggatgtt gtgagacacc cccgccatgc ccgttgctcg acgccatcaa gtccttcgcg
    19801 cgggcccggg cttggttctc ccggatcgca atgaactcca tctccggcgt gatgatgcct
    19861 ttcttcgcgt agtgcatctg gctgacgttc cgtccggcct tcgcgcggag cggtttgcgg
    19921 atgtgcgtga agcgcaggtc cgcgagcttc ggatcagccg cccgttgacg gccgtattgc
    19981 gacgtcactt gcgggagttc ttccgtatcc tgccgggctt cgatccacat tcggcgcaag
    20041 ggcggtaacc cggcgcggac atcgatcgtg acattcggat cggtataggg gccggaggtg
    20101 tcgtacacgg tcaccggttg gttgggcgtg ccgccattgc cgttggtgga gtgcgtcggt
    20161 gtaaggctga tttcacgcat cggcacgcga acgccgggtt gggacccttc gacatgcacc
    20221 ttgcgcgagg ccgcgaatgg ggtggtggtc aggcgcgccg tcgagggttt ggcgccgtgt
    20281 ccgttgctgg aaccgttctg tgtatgggcc tcgctcatgg cggaattcct ttcgtcgaag
    20341 gtgagcggtc tgatggccaa aataaaaaag ccgcatccag cttgggtgcg gcttgaagcg
    20401 atctcgaagc cagtgaaccg gtcgcttccc tacgctggta ttacccaggt caggttgtga
    20461 gggtcgcccg atcgctcggg ctctcagccg gatggcaccc ctagctgtcg ttggtgatcg
    20521 taccgacctg tcagggcgaa gtcaatcttc tggaaggcct agtggcaagg tgcctcatgg
    20581 ctcatgtgga cggtcgttac tcggcaatac cagcgcaatt ggctccgagc cagcggctct
    20641 tgaagtcgat gtgaactttg ccggcacggg gacggtcggt gtccatgctt cccacgagca
    20701 actctgccgt ctgggcttcc acgctcatcc gggacgttga ggcctgagga gcaggacacg
    20761 ttcgttcaag gacgagtttc gcggatgatt tcgacaccac cgaggtttta cagcctggct
    20821 catcatcatc attttctttg atgatgcgat tctggtccag gtcctctttg gtcaggcagg
    20881 ttttgacgga atgggtcttc ggtttgccgg aacgtgcctg catggattgt tcgactttgg
    20941 cacgttgttc aggcggcatt tttgccagaa catccggtgg gacgagcatg ccgctggatt
    21001 gagtggtgaa agtcatctcc caggcgccgg gtttcgcgtt gaatgattcg gcctgtgccc
    21061 cggaggtcgg ccagagcagg acggggttcg acagaagtcc acatgccacc aggtacacaa
    21121 agcggccaag cgtcggtgtc atccgttttt tcatgggtcg gtctcctcct ctccggggtg
    21181 actaggatgg tgcctgcgca atcatacgca gttctgtcgg agaaatcacg atgtgtgaca
    21241 gcacactcgc tttctctcct gagcgggcgt aagcttttct taagaccaat gatgcactgc
    21301 gctcacagaa atggaggcac atcatgaacg ggagaaattt ttggatcggg ctggtcgtgg
    21361 gagcgagtgc gatgggaatt cttggtcagt gggggcctgc cgtcgcgggc aaggacgcca
    21421 ttcaacccac ctgtatcccc gccgccgcgg tggccgaata tctgcacagc gtcattcagg
    21481 ccgatcgtac cttctacacc acggatgtcg tcgagcggat gcagatgcgc gggattgcct
    21541 ttgccgcgga aaactggcgc gaaacgtcgc ggcttccgct tccggcccaa tatttgttgg
    21601 aaacggggcg gctcgtggcg gcgggacgaa gcggggtgca ataccggttg atcagcaact
    21661 gggcgatcaa tgccaagaac cggccgatga ccgactttga acgagcgggc ctgacggaga
    21721 tcctcgtcaa tcctgatcag ccctatacgg cagtgaccac ggagggcggc gcccctgttt
    21781 ttcaagccat ttatgccgac aaagcggcct cccagtcctg tgtcggttgc cacaatgccc
    21841 atcccaatag tccgaagaaa gatttcaagc cgcaggatgt catgggaggg attctgctca
    21901 ccattccgct gccgcagtag agggatgtgc ctgttgagga cctagaaggg ttgccacgag
    21961 acttgttgaa gtccgacatg tggatgagtc catggatcac ctctcacatt cctctcgcat
    22021 cgcgcgcccc cttcgcccaa ttgccccagt tccttctagg ccatctgctc cgactcattt
    22081 cattgcgtag ccgcgaaagg gtgtcgtaga attattaaga ccgtgtctct tcatgacaca
    22141 gggtatggac tcaaccgaaa ggctgcaggt gaaaacggtc accacgcttc cccgtcccat
    22201 taccgactat cagtctctgt ctgccgaaga actcttcgaa cggacccgtg cggccaaacg
    22261 ggcgctcggt gaccgggtca tggttctcgg ccataattat cagcgcgatg aagtcatcca
    22321 acatgccgac ttccgtggcg actcgctgat tctcgcgcaa gtcgccgagc agcgttccga
    22381 tcggccctat gtggtgttct gcggcgtgca cttcatggcg gaaacagccg atgtgctgag
    22441 ccgttccaac cagactgtta ttctccctga catggcggcc ggctgttcta tggccgatat
    22501 ggcggcgatc gagcaggtcg aacagtgctg ggatgcgctc ggtcgggtgg tgccggtgga
    22561 ggagacggtc atgccggcgg tctacgtgaa ctccgcggcg atcttaaagg ctttctgcgg
    22621 cgagcatggc gggctgacct gcacttcgtc aaacgcgcgc aaggtgatcg aatggagctg
    22681 ggcgcgacgt gagaaaatcc tgttcttccc cgacgagcat ctgggccgga atacggcgaa
    22741 caaaatgggc atcccgcgcg agcagatgat cgtctgggat ccgtatatgc cgcgtggcgg
    22801 caactcggtg gaggcgattc agcgcgcgaa gctgatctta tggaaaggcc attgcagcgt
    22861 gcatcagatg tttcagccgt cccacatcga ttacgtccgc aagaagcatc ccgaggtaaa
    22921 agtcattgtg catcccgaat gtcacgaaga tgtcgtcaac aaggctgatc tcgtgggatc
    22981 gactgagtac atcattcgca cgatcacggc ggccccggcg gggaccacct gggcggtcgg
    23041 gacagaactc aacctcgtca atcgcctgaa gcatgagcaa gccgataaga agatcttttt
    23101 cctctcttcc acggtgtgcc aatgcgccac gatgtatcgc atcgacgctc cacatctctg
    23161 ttgggcgctg gagaatcttg ccgatggaca cgtcgtcaac cggatcgtcg ttccggacga
    23221 cgaaaagcaa ctggcgaagg tggcattgga ccgcatgatg gcgctcagct agcaaactgt
    23281 tgagaaaggc cgctggctgc gttctcgcgt cgctcgcatg ttcaacgtac cgcaagggta
    23341 cgcctcacat gctccctcgc tgcggccttg ccggtcgacc tttctgaaca gcttgcagga
    23401 cagccaggtc ctaccagtca ccttgctaat ggttccggct gccaacaaac cactggttcc
    23461 tctcgccccg attcggtata gtcctctctt tacgcgtact tcatggccat ttcgtctcgc
    23521 agctagatca atctatggac tataaatcga ccctcaattt accgaagacc gactttccta
    23581 tgaaggcgaa cctgccgcaa cgggagccgg agatgctggc ccgttgggca caggaacggc
    23641 tgtacgaacg gatccaggag tctcgccagg ggcgtgaaca atacatcctg catgacgggc
    23701 cgccctatgc gaacgggcgg atccatattg gccacgccct gaacaagatt ctgaaagaca
    23761 tcatcgtcaa atcgaagacg atgtccggtt atcaggtgcc gtacgtgccg ggctgggatt
    23821 gccacggtct acccatcgag caccaggtcc tgaaggaact gggcgacaag aagcgcgacc
    23881 tggatgcgct cgcgatccgc aaactgtgtc aggagtatgc ggccaagtat gtggccatcc
    23941 agcgggagga attccagcgg ctgggcgtgc tcggcgaatg gcagcaaccc tatctcacgt
    24001 tgaatccggc ctacgaaggc accatcatcc gcgagttcgg ccggtttgtt gagcgcggcg
    24061 gcgtctataa aggcttgaag ccggtcttgt ggtgcacgca agaccagacc gcactggccg
    24121 aagccgaggt tgaatacgac gaccacacct cgccctcggt ctatgtaaag tttcccctgg
    24181 tgagcccgcc ttctgtgttg agcaagaggt ttgggccggt ttcgttccct gtcgaagcaa
    24241 cacgcgcgtc ggtgctgatc tggacgacga cgccgtggac cctgccggcc aatcaggccg
    24301 tttgtcttca tgccgacatc gactatgcct tcgtgctggt cggggacgaa ttgctggtca
    24361 tggctgagaa gcttgtcgag tcggttgcca aggcgtgcaa catccccacg tacacgatcg
    24421 tcgccgtgaa aaagggtcgc gagggatttg agggcttgga ggcgcaacgc ccgttgacca
    24481 caggtctctc tccattgctc ctgggcgatt tcgtgacatt ggagcaggga accggatgcg
    24541 tgcacatcgc gccgggccac ggcatggaag actatctgct ggtgctggat cacaatgcca
    24601 aggcgagtgt cggcgagcga ctcgaaatcc tggctcccgt ggacaatggc gggaagttta
    24661 ccgaagccgt tccggagttt gccggtcagc atgtcttcaa agccaatccg aaaatcgtgg
    24721 agcgcctgaa gggcaatggc cgcttgctcg gacacggctc gctcaaccac tcgtatcccc
    24781 attgctggcg atgtaagcag ccggtgatct ttcgcgcgac cgaacaatgg ttcgtctcta
    24841 tggagacgaa tgatctgcgg aaagaagcgt tggcagagat tgaacgggtg cgctggatcc
    24901 cggcctatgg ccgcgaccgc attaatggaa tgatcgaaaa tcgccctgac tggtgcctgt
    24961 cacgccaacg ggtttggggc acgccgatcc ccggcttcac ctgcctcacg tgcggcaagg
    25021 tgctggccca tccccgcgtg atcgatcatg tggcggatct gatcgggcaa catggcaccg
    25081 actactggtt tgccaaccag gctggcgcgt tgctgcctgc cggcacgcag tgcgaaggtt
    25141 gtggcggaac tgatttcgag aaggagcgcg acattctgga cgtctggttc gagtccggcg
    25201 tgagttatgc ggcggtgctc aagcctcgac aatggtatcc ggcggatctg tatctggaag
    25261 ggtcggacca gcatcgcggt tggttccaca gcgccctgtt gtcgggtgtg atcaccgatc
    25321 atcgtgcgcc gtataaagct gtgttgaccc atggtttcgt gctcgacggg gcggggcgaa
    25381 agatgtcgaa gtcggcggga aacgtcgtgg ctcctcagga cgtcatcaaa caatccgggg
    25441 cggaaatcct gcgcctctgg gtatcggccc aggattatcg cgaagatctt cgaatttcac
    25501 aggagatcct gaatcacctg atcgaagcgt accgaaagat tcgcaatacc tgccggttcc
    25561 tgctgagcaa tctgtacgac ttcgatccgg cgcagcatcg cgtgcccttc gagcagttgc
    25621 ccgaattaga ccgctgggcc ctcatgcggc tgagcgacct gattccgcgc gtgcgcaagg
    25681 ggtatgacga atttgagttc cacacgatct ttcacgcgtt gaacaatttt tgttctgtcg
    25741 atctgagcgc cgtgtacctt gatatcctga aggaccgttt gtatacgttc cggaaggatt
    25801 ctccgctccg gcgtggttcg cagacggtgt tgttcgacat cgtggttgcg ttgaccaaat
    25861 tgatggcgcc cgtgttgagt ttcaccgccg aagaaatctg gagaacgttg cctgagtctg
    25921 tgcgcacaga agcaaaagcc gacagtgtgc atatcgccat gttcccagag gtcgatccgc
    25981 gctgggctga tccgatgctg gcgcaacggt gggagcaggt gctcgaggtg aggtccgccg
    26041 ttcaggccgc tctggaagtg aagcgtcgcg agaaggtgat cggcgcgccg ctggaagcga
    26101 gagtcgtgat cgaggcgaat tcggagcggt atgaattcct gaagcggtac gaacaggagc
    26161 tctcgtcctt ctttatcgtg tcagatgtgg ttctcactca ggccggtcat ctcgcggagt
    26221 cccccgggta tagcgtgacg gtggataagg ctacgggcgc caagtgcgag cgctgctgga
    26281 actatcgatc cgctgtgggc acctctgccg accatcccac actgtgcgat cgctgtattg
    26341 aggccgtccg ttgagccagt ccatccgtta tctgctgctc gcctcgctga gcctggcgat
    26401 tgtcgtgttg gatcaagtca cgaaggtcta tgtcatggag accatgcggc tccatgagtc
    26461 cattccagtc atcgccaatc tgttcagtat cacctacatt cgcaatcccg gtgcggcctt
    26521 cggtttcctc tcatcgagta gcagctcgtt caggtttgtc ttcttcggcc tgacatcgat
    26581 ctttgcggtg ggcttgctcg gcatgatcat ggtgcgtatg ccgaaagaag actggatggg
    26641 gcggctcagc gtggcgggaa ttctcggcgg agccatcgga aacttattgg atcggctccg
    26701 ttacggagaa gtcatcgact tcctcgattt ttacgtcaac gggtatcact ggccggcgtt
    26761 taacgtggct gattccgcga ttaccgtcgg agtcgtgttt ctaatacttc acttcgcgac
    26821 ggagaaggaa ccggcggatc agcctgtcgc ttccgagcag ccgccttcct gaccagcgca
    26881 tttccgacca tcacaccggc aaggtgatga tgaatccgcc ctgctcccga aactgccgtt
    26941 gctgcttgac cgaaaacatc gcgagcggtt cgctgtggca gaactggcat tccttgagcg
    27001 taatcacggc ctgaggctcg ccgattccca ccaggtattg cttcgccagc gccagggctt
    27061 tttcctgact ggtcgtcata acatcgaagt gcagtttgcc gttctttcct ttgacccacg
    27121 tatcgtacac gtggacgctg tccatgttac ttgccatgac gattcagctc ccggttatgg
    27181 tttggttatc ggaccacgag cagcacaatg acgcccagta ccatgcggta ataggcgaac
    27241 acgctgaggc tgtggcgttg cacaaaggtg agaaaggcgg cgatcacggc ccaggcgacc
    27301 acaaacgaca ccaccaggcc gatgccgagc gccacgtagt catcctgaga aaacgaggcc
    27361 tgcgatttga gcatctggta gatcgtggcg atgatcatgg tcgggagggc caggaagaac
    27421 gaatattcgg tggccacgcg ccggtcgagg ccggccagca gaccgccgac aatcgtggaa
    27481 cccgagcggg acatgccagg gatcagggat gcgcattggg ccaagccgac cagcagggcc
    27541 gatcgtggcg tcacctgtag cagctctttc acgcgcacgc ggctctgcat tcgctcgacc
    27601 accagaatga tcacgcctcc gacgattaaa gaaattgcca cggtcgtcgg cgagaagaga
    27661 taggccttga tcgacttgtg cgcgacgaat cccaccagcg cggcgggcag gaaggccagg
    27721 cccaatccaa tcacgaacca gagattgggc tgggcattga tcgattcctg aagggtcgtt
    27781 gcccaggatt tcgtgccccg ggtggcgatc aacgagcgaa actcctgttg ttcgcgtagg
    27841 gcatgggacg cgagcgacgc cagcttggcg cgctcgtaag cgatgatcgc gagaatcgag
    27901 ccgagctgaa tggagatctc cacgttggag gcgatatccc ccgtaaaccc gagggcatgc
    27961 ccgacgagga tgagatggcc ggtcgaggat acggggagaa attccgtcag tccttcaatg
    28021 atgccgagaa tgacggcaag ctccgggccc cagttcatca tagtgtgtgt gagatggtgt
    28081 gtgggatgct gcggttggtt gcgtagttgt cacgaatcgt cgttgcataa tcccagactg
    28141 gtcaccggca gtcaagcgct gtcgagttta cggcgacctc tttctcgatg tggcgcgtca
    28201 tcgcaaccgg tgctgcgcaa tcggcaaact tgttgacaaa gttgaagtga tggcatacac
    28261 acaacaagag agaagaggtc cgatcggtcc agatcgaaca ggggaggatc gcatgaggca
    28321 tgtgtgggtg gctgggcttg cgctcatgag cgcgatggcc gtcagcgggt gcgtaagtga
    28381 caagaaatat catgaggcgc ttgccgatgc cgatgccacc aggggagaac tggagcgcgc
    28441 gcgagcgcag aaaaatgccc tggagcaaca ggtcaagacc ttaaaggatt tgaacgcgaa
    28501 gttcggttcc gaaagccaga tcgcccgtga tgaactccag cgtatccagc acgggcgcga
    28561 taaagagcgg gataccatcg atgtcaggac caaggagctg gaagacaagg tcaagcagct
    28621 gagcgcgcaa aaccgcagcg tcaagcagga gtatgaagaa gctcgccgcc acaatgagca
    28681 attgaagtca ttggtcgcgc ggtatcagaa agaaatgaaa gaccggtcgc gttccctgtc
    28741 atcgggaatg gagtcgccgg ccttgaccgc gccgctgggc ggcggcggtg cttcttcgaa
    28801 agctgctcct gcgccggccc catttgaggc accggctgcg ccgctgctca atatcaacaa
    28861 ggcgccgtcc tcggatctcg tgctcacgct gggtattaca caggatgtgg cagaccgcat
    28921 cgtcagtaac cgtccctaca gagtgaaggg cgaactcgtc gccaagaatg tggtgacgaa
    28981 ggatgtgttc gacgacatca aagaccgcat taccgtcagc ccctaagcac cagtgagcag
    29041 gtccaccgct ggtggatcac gtgacatgaa cggccgtttg ccattctggc aaacggccgt
    29101 tctctttcgg ttcgctccgc gctcagaggc cccatcgccg ccctctgcct gacatcgtca
    29161 aattgttttc tgctagaatg cccgcagtac ctgggcgaag aggaacgcct gttcatgcgc
    29221 cgtgtcagta tcattgtcgg tgtgcttgcg ctcggcctgg ccatcgccgg ttacgtgttt
    29281 ttcaacggcg agcggaaggt tcctctgcgc tttcgcacgg ttcccgtcga gcgaggatca
    29341 gtcgtctcgc tggtcaccgc aaccggtacc atcaatccca ttacgacggt ccaggttggc
    29401 agtcaggtct cgggtatgat cgagagcctg catgccgatt tcaattccaa ggtcaaggcg
    29461 aaccaggtcg tcgcacggat cgatcctttc ccctaccagg ccaggcgtga tcaagcggtc
    29521 gccagccttg ccaatgccaa ggcggcgttt gaaaaggcgc ggatcgatct ggctcagcgt
    29581 cggcgcgaac tggatcgagc aaagtcgctt atcggccagc agttcatttc gcagaatgaa
    29641 gtcgatgttg ccctgaccgc ttccgagggc gccgtcgcgc aactgaaagt gacggaagcc
    29701 gccgtgaagc aggcggaagc catgttacaa gcggccgagc tggacctgaa gtatacggtc
    29761 atccgctcac cggtcgacgg agtagtaatt tcccgtctgg tggaagtcgg tcagcgtatc
    29821 tctgccagct tttccattcc caccctcttt ctgatcgccg aggatgtgac caaaatgcag
    29881 gtcgatacca atgtgagcga ggccgacatc ggcggcattg tcgacggcaa agcggcgtca
    29941 ttcaccgtgg atgcctatcc cggagaagcc tttcaagggc gggttcgcca ggttcgcaat
    30001 gcgcccatca atattcaaaa cgtggtgacc tatgacgttg tcgtcgaatt cgagaatcct
    30061 gagtttcgtt tgaaaccagg tatgaccgcg aatgtctcca tcgtcgtcaa caagcgggag
    30121 aatgtgctga aggtgccgaa cgcggccctt cgcttcgtac cccccaaggc cgttcgagat
    30181 gagaagggag aggccgggcc gaggagggat ggcgagcgcg ccggcggcag gcctacgatc
    30241 gcgagtgggt ctcctgaatc agggaaccgg caatggggtg tctggaggct ggatggtgcg
    30301 ggagagttgg agcgcgttcc ggtcgagatg ggtatatcgg atcggtccta tgtcgagatc
    30361 actgctgccg gtatccagga aggcgaccag gttgtgaccg gtatcgagtc tccacgcggt
    30421 gagcgcaaga gcggagaact cccaccgggc ttcggtggcg gccaacagcg cggcgggcgg
    30481 cgggaccgtg ggatgtagcc atggtggaaa cagtcgcgtg cgatcccgtt tgtgagggca
    30541 cgatggctcc cttgatcgtc tgcgaagacc tctggaaaat ttatcgcatc ggtgatgtcg
    30601 aggtgcaggc gcttcggggc atcaatttga caatcgaccg cggcgagttt gtcgcggtga
    30661 tgggcacgtc ggggtcgggc aagtcgacgc tgatgaatct actgggttgc ctggacaagc
    30721 cgtcgcgagg ccggtatcgg ctcgacgggt tggatgtgag tacggccaac ccagaccttc
    30781 tcgccgatct tcgcaaccgg cagatcgggt tcgtgtttca gaatttcaat ctgatccccc
    30841 ggaccagtgc attggaaaat gcgcaattgc cgctgtttta tcgcggtgtc tcgatcaagg
    30901 agcaacgccg gcaggcggcc gccgcgcttc agcgagtcgg gttggccggg cgggaacagc
    30961 attatccggc ccagctttcc ggtggtcagc agcagcgcgt cgccattgcg agggcattgg
    31021 tcggcgcccc ctcaatcctg ttcgcggacg aaccgaccgg taatctcgat accgcgtcga
    31081 gccgtgaaat tatggatatc ctcgaacatc tcaaccggga ggacgggatc acgatcattc
    31141 tcgtgaccca cgaacccgat atcgccgcgt atgcgtcccg cgaactcgtc atgaaggacg
    31201 ggcagatcgt gcaggatgtc cggcgcgagc ctcacctatc tgcggtcacg tagggccaga
    31261 tgccggcatt cgttctgctc actgtcatga cggcgttgcg gattctgagc cggaaccggc
    31321 tgcgggccgg tctcaccatg ctcggcatcg tcatcggcgt gggagcggtg atcgccatgg
    31381 tgagtatcgg gcaaggggcc agggcggcgg ttcaggccca ggtggcaagt atggggacaa
    31441 atgtcatcgt catcatgccc gggtcgacga cggtcagtgg tgtgcgaggc gcgcagggcg
    31501 gggcggtgac gttgacgatc aacgatgcgg ccgaattgaa aaaacggagt ccgctcctgt
    31561 ccgacaccgg gtgggcgaag cgcgatgtga tgcaaatcgt caacgggaat cggaactgga
    31621 atggccccgt caatggagtc tccccgagct acctgacgat tcgcgactgg tcgttcacga
    31681 gtggcgggcc cttcacccag acggatatgg acagtgcggc tcgcgtggcg ttgatcggcc
    31741 agaccacctt ggagaatttg tttgatcctg gcgaagaggc gatgggagcc acaattcgca
    31801 tcaagaatgt gccgtttcaa gtcgttggag tattggctcc gaaggggcag tcggcccagg
    31861 gcacggatca ggatgacgtg attttcattc ccttcacgac ggcggagcgg agggtattcg
    31921 gcagccagtt tctcggatcg gtcggggcgc tcttcgcgtc caccgaacag agcggcgatc
    31981 tccccgaggc cgtggagcat attcgggaga cgctacggct gaggcacagg ctggagccgg
    32041 atcaagcgga tgattttacg atcaggacgc aggtcgatat cgggaaggtg caggaaagta
    32101 ccagtcaaac gctcacggtc atgttgtttg ccatcgcctc cgtctctctt ctggttggcg
    32161 gtatcggcat tatgaacatc ctgctggtct cagtcaccga gcggacgaag gagatcgggg
    32221 ttcgtatggc cgtcggtgcg aaacgcattc atatcctgac ccagttcctg atcgaagcga
    32281 tgacgctgag tctattcggg ggcctgatcg gcgtgattgt gggcatcgtc ggcgcacgac
    32341 tcacgacggt gattgccggt tggccgacca tgatttcagt cgatgccgtt ctgacggcgt
    32401 ttctgttttc cttggctatc gggctctttt tcggactcta ccccgccaat aaagctgcac
    32461 gtctcaatcc cattgaagcg ctccgttacg aataggcctg catgccgcca gggcttctcc
    32521 agcggtccga tcttctcgat gaggggagca cacggatggg gctgaggtca gtgataggct
    32581 cgttgaaatt cttccgggat tgttcccaac accgaacgga ccccgcgcgg aggggcctct
    32641 tcatcctgat tggcgaggtc gatgacgagc gggacgatat acggttctcc ggaagggtcg
    32701 tgggtgatcg tgacgatggg ttggtggagt ttgcctgagt tgatgacgga gacgatggca
    32761 cgttcgccgg tcgtcagctg gacataactg taaacggggt aaatgcccat gactttgacg
    32821 aagagggaga tcagccggct ttcgtatcgg ccttcctgtc cctcctggta gagccgctgg
    32881 agcgattgat gcggggtcag gggcgaggct ccgccaaagc ccgtcatcaa ttcgtcgtag
    32941 cggtccgtca ccatcacgat ccgggtcatg tccgacgtga acgcgccgcc ggtttccgct
    33001 ggaaagccgc tgccgttcag gtaggcatga tgttccgcca caatctgttc caccggtttg
    33061 gtgaatccgc cccggcgttc caagagaatg gcgcccgagc gcgcgtgagc ttcataggtc
    33121 agacggtttt gttcagagac tgtggtcgag gtgtcatgca cgcgccggag gatggcgggt
    33181 ggcacctgca ggagcccgat atcgtgaagc agcgcaccgg tggccagttc ctggatcgcc
    33241 attagattgt agtcagccgc atgggcgagg atcatcgaga aactgcaggt ggccagtgca
    33301 tgctgactga ggggcgcatt ggcctctcgg ccttggctga acaccatgaa caaggcagaa
    33361 gtattgaggg cctgggcgac cgcgctgatg gcatggacgg catggctggc ctcctccgga
    33421 tcgaccacac cggttttggc gatgcgggag aacgccgaat ggacggattc ctcgagtttg
    33481 gctcgcgctg acctggccgc cagcaattct tgcgtcatgg tggcaagaga ccggatctcg
    33541 acggacttgc ccatctgcga agtcgcaggt tgcgcggcaa cagggagcgg ggcttgggac
    33601 ggggccattg gatcttgaag atcgagtccg cgagagggat cgatgctcac ctgtttcacg
    33661 cccgcgcgcc gcagcttctc gatctgctcg tcagtgcgaa tcaggaacga gtggcgcatg
    33721 aagggggaac gaaaccaggc gacgtcgatc ttggcgacgt gcatgccgat tcggagcgca
    33781 tcaattgtaa tgggtcggta tgtcatagcg cgtgctgccc gccggcgagg cggaattcaa
    33841 acgggtgtcg ccccaaccat cctatcggtc ttgcccgttg tcgattggcg gcttggggat
    33901 caccgcgacc tgtgccttga gtgaggcggg aaaaaacgga tcaggcgccg tcgacggcgc
    33961 caccgataac cggatttcca tgcgaggatt gtcgcgatcc tggtgcttat agagatgtgt
    34021 ttcgaccact cgattgtcgt tcagtcccag cccctcacac agggcatctt gcgcgatctt
    34081 gagcccgccg tcagtatccc gtcgcagcgc agaggcgaag aaaaaatgga tcgagagaga
    34141 caggctcgcc tgttgcaagg tctgtcttag agtagcacga tgaggcgatt gggcaagcgc
    34201 aaccacaatt tgttgcccga caaagtcttt atacgtacgt cctttcgcgg agagcaggcg
    34261 acgcccgttg accgtggcgt actgatgatt gatgcttggc gggacgggca atgtgagggt
    34321 gatggagtcg atggtgacgc tcaagccagt acctgccggg gtagggaacg acagcgcatg
    34381 gcgattcctg ttggactgtg tgggaatgag cggtgctcgt tccatgggta cggccggctc
    34441 ggacagtgac ctgaaggacg tggatcggat cgtaacgggg gattgtcggg gacgggatgc
    34501 gcggcgcaag ggcctgccta tagaagattt tggatcttag ccatatcctg ctcggcccgg
    34561 tcttcgtttc tggtgaggta gcgccgccat tcagacgggc cccagatttc cagacgatga
    34621 tacatgccca cgaggacgag ttcctgatcc tcatccatcg ggacgagttt gcggagtcgg
    34681 cttggaatca acacccggcc ggctttatcg atgtcagagg cgccggcttg ggccatcaca
    34741 tggtgcatga acaggcgggt ctggtcctcg tccagggtgg ctctcgtgcg ttccaggacc
    34801 tgttcccatt ccttggcgga gtacatccag agcgtctgct cggtgttctt caggaacatg
    34861 acctggttac cctcggcttg gaatcgctca cgaagcggag aggggatcag gaaacgtccc
    34921 ttttcatcga ccttgcagag atgttctccg gcgaacatgg gcggcttcct ccgtttcaac
    34981 gccgatggta ggagacatgg ctgatcctgt caagagaata ttcttacagt gcgtgtcagt
    35041 caaaatccgt tccgtcgatc cccgatgctg gcgcttgccc atcctccatc gctgcatcga
    35101 ggtcatcgcc cagatcctcg cccatttcct gccccatctt cttcatgaac cgcgccatgc
    35161 tctggggatc gttttcatcg agtccgctga gattgctcgg gtcggagagg gcctcaagcc
    35221 gtgcttcctc cgatttgggc gaggcgaatc gcgacagcag ccgttccatg tcggcgctct
    35281 gacaatgggc gcaagtctgc tgcggaacgg agttcgcgtt gagaatcagg cgtgtggtcc
    35341 gttttccgca ctgtcggcaa cgatactcat agatcggcat gggttaggct cgctggaatt
    35401 ccgtttggtt gagagctgac ggcggcagcc acgtgtccgg caccatcccc gcatccgcgg
    35461 accgcgccag ggcgaggacg gcgacctgtt tggctccggc cgtaaggagg actctggcgc
    35521 attcgctcgc ggtcgtgccg gtggtgaaca cgtcgtccac cagaagaatg cgtgctccgg
    35581 tgatctcctt cggctggcgt atggcgaacg ccttgcggag gttctgtaga cgcgccgcgc
    35641 gcggcagcga ggtctgcggg gcggtatcga cggtacgaat caggttccga taggataccg
    35701 gtagtctgcg ggcggaaccg atgcggtcgg cgatgagaag cgactgattg aactcccgct
    35761 gccggagtcg agtggggtgc agagggatcg gcatcaggac atcgacatcc aggcgatcgg
    35821 gaatcgcctg gaggagtaac acgcctaatg cgtccgccag cgccaccttc cctcggtatt
    35881 tgaagagggc aatggcatcc tggagcggag aacagtaggc atagggagcc cagacctggg
    35941 agtaataggg ttcgcgggta cgacagtcct ggcattcgtg cgtcgggctg taggtgaggg
    36001 ccgagggtga agcgaacggg cgatgacacc gtggacagga aggcccgcgc aatggtcgaa
    36061 tcagctccca gcaccggcgg cagaaaaagg gcaccggatc atcagcgagg ggttgcgcac
    36121 aggtggtgca atccatcgga agcagcagcc gcgaggcctg cctgagaaag tccattatca
    36181 ttgtcgacta cgtatcgttg acgtgaagcc cttcagcctg gtgggattgt ctaaggaacg
    36241 ctccagacct gtcaaggttg tgggctgtaa agggggtgtg atatagcacc attcggtctg
    36301 catgcgggcg atttcaccat tggacagggt tggccggctg acgatgcttg gaacatccca
    36361 cgatcattca ccgtccagtc ctgctgatat gagcggttct gcggccccac tcgtgagcgt
    36421 acacaacctc tcgaaagaat atcgccgtgg cggaacggtc ttgtgcgctc tgcagggcgt
    36481 cacgcttgag gtaaaggccg gagagttctg cgcgtttgtg gggcccagcg gctgcgggaa
    36541 aagcacgtta ctcaacttga tcggaggcct ggatcaaccc acctcgggaa ccatcatgat
    36601 cgaaggtcgg gccgtcaccg atgcgagcgc gacggaatgg acccgtctcc ggcgcgagtt
    36661 gattggcatt gtgtttcaag cctttcattt gattcccggc cttacggtcg cggagaatgt
    36721 ggcgttgccc atgttactca aaggagagca aggccgcgcc gtcacggatc ggatcgatga
    36781 agtcctgcag gcggtgggga tggaggcacg ccgttctcat cgacccagtg aattgtccgg
    36841 tggcgaacag cagcgggtgg ccatcgcccg cgcgatcgtg catcggcccc gtctgatttt
    36901 ggcggatgag ccgacgggaa atttggactc caagcaaggc gccgatatcg tgaacctctt
    36961 ccggaccctt cctcaacggt tcggccattc cgtgttgttg gtgacccaca gcgacagcgc
    37021 agcagaagct gcagattatg tctggcacat gcgagatggg cgtttggtca atcgcattgc
    37081 acactgattc cgggagggtg acggatgctt actgttccta acgctggccc tgttcgtgat
    37141 gcagaagaga aaggatcggt atgagtctca gcatgaccat tgcgggcgtc acgtttccga
    37201 gctgtttgat gaatgcgtcc ggggcgctct gtatgacgcg ggaggaattg ctggctttgg
    37261 gacgctcgcg ggccggcgcc atcgtgacca agtcgatgac ggtggaaccg cggggcggaa
    37321 atcctgaacc gcgttattac ggatttcccg gcgggtcgat taattccatg ggacttccga
    37381 atctcggcta tctggcctat gcggacctca ttccggagct gaagcagttc ggcaagcctg
    37441 tgattgccag tattgccggt ctgtgcgaag acgactttct caccatggcg cgcgtgatca
    37501 atcacgcaaa acccgatctc atcgaggtga acctgtcttg tccgaacatc cccggcaagc
    37561 cacagatcgc ctatgacccg gtcgattccg aacggcttct gaagcgggtg cggccgctca
    37621 tcacggtgcc gatgggcgtc aagctgccgc cctattttga tccggctcac catgcggtga
    37681 tggcggaggt gatcggccgt tgcggagtgg actatttgaa tttgatcaat tccgtcggca
    37741 acggcctcgt gatcgacccg aagcgtgaaa cgcccgtcat caaacccaag ggggggttcg
    37801 gcggattggg aggttcgttg atcaagcctg ttgccttggc caatgtgcga gcattctgga
    37861 agctgctcgg cgggcgcatt ccgatcatcg ggaccggcgg agtcgtgcag gggctcgatg
    37921 cgttcgagca tgtcctctgc ggggcgtcag ccgttcaggt gggcacggtg ttggtggaag
    37981 aaggtgtcgg tgttttcgaa cgcctggagc gtgaactgga agccgaactg tcttctcgcg
    38041 gagcgcgacg ggtggaggac tatcggggca ggttaaaaga gttgtaacgc gtggcgcgga
    38101 gattccacgc cacgcggtct tcggtcggat tatctaaagg caaagttctt cggcaggaaa
    38161 ccttgctgca gcgcctggcg gagcagttgg gccacgttgc ggaccttcaa tcgccgcatc
    38221 aagttaaacc gatgcacctc aaccgttcgc acgctgatat ccagacggcg ggcgatgtcc
    38281 cggttggtgt ttccttgcga caccagttta agaatttcct tttgtcgggg agtgagtccg
    38341 tctgagcgcc ttgtgcgtcc gggagacgcc ttggccaact tcacgggctt tcgtttcttc
    38401 gctgcgggag cagctttggt ggtcttcgag gatttttttg cttgaggtcg tttgcgtagt
    38461 gccataaaga ttttgtaccc caatttctac tgaaagtaat cttaacatac ctgggtaaat
    38521 ctgtaaaaac aattactaga ctgtaggacg aacgcgcgta cgtatgtcgt tgtttcactc
    38581 ttctttactg agagtctgtg cgagcctggg gtggacacat ttgtccaccc atccggggcg
    38641 gacagcgttg accatgttcg gtgtcgggct tggcgtggcg gccactattg ccgtccaaac
    38701 ggccaacgtg gaagtcctgc gttccttcga ggaatcagtc ttgacggtag ccggcccggt
    38761 cacgctggag gtgtcggccg gggaaaccgg cttggacgaa cgtctgatct ccaccgtacg
    38821 gacggtcccc ggtgtcttgt cggctcgacc ggtgctggag gtcggggtgc gggtcacaga
    38881 cggccggtcc ccccggcagt cgttttcgat ccttggcctg gacctattgg aagagttgag
    38941 cccggaggga ggacgtgtcg tttctccagc gaatcgaggg gagggggctg gtgagcgaat
    39001 gccactggaa gacctcctgg caagaaatgg ccttctgatc gggcacgccc ttgcgtcgga
    39061 gttgagtctc gcgccacggg ctcagttggc gctgcagagc ggggatcagc acgtgtcggt
    39121 gtcgattatc ggagtcatgg gccggcgtcc tggtgggcct tcgccctggg accgcatagc
    39181 ggtgatggat attgcggcag tgcagcggac gttcggactg atcggccgcc ttgatcgtat
    39241 cgatgtggtg acgacgccca cttcgtcggt tgagcaggtg gcggaggcca tcgggcgggt
    39301 tttgcccccg gctaccaccg tacgtcgccc gattcagcgc agccagcagg ttgaatcgat
    39361 ggtgggggcc tttcaactga atctctccgt gttgagcatg gtggggctgt tggtcgggat
    39421 cttcctgatc tacaacacgg tctcctttac ggtggcgcag cgacgtcggg aggtggggat
    39481 tctccgcgcc atcggcatgt cggagccgat ggtcgtcgct gtgtttctgg cggaagccgg
    39541 agtgttcggt gtcgtgggcg ggctgctcgg aggcatgctc ggcctgttgt tgggcgatgt
    39601 gcttgtcgcg ctggtcggcc ggacgatcca tgatctgtat acaccgctgt cccattcgac
    39661 aggaactgtt ggttttcctg tcgggtctgg ccggttattg gtcgaagcgg tattgatcgg
    39721 gagcggagtg tcagttctgg gcgcgcttgg tccgagcgtc gatgccggac gtacgattgt
    39781 ggtcgcggct ctggcaccgg gtgagtacga cgtcgctcaa cgtgttcgcg cggcgtcact
    39841 gggggtggcg ggtggagtgc tgttactcat cgctctggga tgcgcattgg ccggcccggt
    39901 gggtggcgta ccgatcttcg ggtacgtggc aaccttttgt cttcttgccg gcctgtcctg
    39961 cctcgtcccc atcctgttgc agagcctctg ccgtacccgg gagttaacga cgctttcgca
    40021 ggcgccgacg ttgggcgggg ccattcggca cattgcccga gagcagacca gccggggcat
    40081 gggaagaaat gccgtcacgg tgtcggcctt tctcgtgggc gtcgcgatca tggtcggcgt
    40141 gctggtgatg atccgcagct ttcgcgacac ggttgaaatc tggatcgatc agaccgtcat
    40201 ggcggacttt attgtcgctc ctgccggatg gccgcacgcc gtgcgcagcg ggtcgtccag
    40261 tccggtactg cctggtgcct ggcgggctcg gttggccaat gctcctctgg tctcggcggt
    40321 agacatgtac cgtgacctgc gtatcgatct gcagggccgg ccggtctcgc tggtttcgag
    40381 agacctggca ctccatgcgg cacggagccg gtatcttttc gtcacggggg agtccgcccc
    40441 aattttggct cgtgccgcgg ccggggaagg cgcgattctt tcggaagtcg tggcgaatca
    40501 tttggcgctg ggcaaagggg atcgattgtc catcgtgacc ccaaagggcg aacagtccct
    40561 ggaggtgctg ggagtctttt atgattatgc caccgatggc ggaaagatcg tcattgatcg
    40621 atccttgtat caacaatggt ggcctgatga cggcgtgacc gtgtttcccg tctatgtcga
    40681 atcgggggcc gatatgggga aggcaagaat ggcgattctc ggcaccctcg ctcaggcgtc
    40741 gcagggaaat ctcatgccga ccgtattgag taatgcagaa ttgcgccagg agattcttcg
    40801 aattttcgac cggacgttta cgttgaccta tgtgctggaa gccatcgccg tgattattgc
    40861 gacgttaggc atcatcaaca cgttggtcac gtccgtggtt gaacggcgtc gtgaattggc
    40921 cactctgcag gcattgggca gtagccgggg gcaggtcacg gcgttgattt tgtgggaggc
    40981 cggctatttg ggattgctgg ggacagggat gggtttggtc ggagggggag ccctggcgct
    41041 catcctgatc cgggtgatca accggcagtc attcggttgg accatccaga tttcgtggcc
    41101 catcggcctg atggcggagg ttgccgcctt ggccctggtg gcctcgctcg tcgcagggtt
    41161 ctggccggcc cgctgggccg ccagacaacc cttggtcgag ggactgcgtt atgaatgaag
    41221 gccgacagcc ggttcggcgg acgaagtggc accctgtgtc ggaagcgcgt ccacttgaat
    41281 gtcgaatccc aggtcttcga tcatgcgcca gacttctgcg gccggttgtc ccggagtggt
    41341 gagatacccg ttcacaaaca ctgaatcggc cgggtagagt gccaatggct ggaggctgcg
    41401 taagttgtgt tctcgtccgc cggcgatacg aagctccgtc cgcgggtgaa ggaagcggaa
    41461 gaggcagagg gctttcaggc accgctgcgg cgtcagcgga gtgcaatgct ccagtggcgt
    41521 gccggaggcc ggatgcagca tgttgagcgg aatcgaatcg ggcttgacct cgcgcagggc
    41581 cagtgccaaa tcgatcaagt cctcatcgcc ttctcccatc ccgacgatgc cgcctgaaca
    41641 gatttccagt ccggccgtcc tggcatgtcg aatggtggcg agccggtctt gaaaggtgtg
    41701 cgtgctgcag atttccgtgt gataggcttc gctcgtattc aaattgtgat tgatgcgatc
    41761 cacgccggct gctttgaggt cttttgcctg ccgttcgttg aggagtccca gggaacagca
    41821 gatctggatc gggacttcct gcttgatgga tcggacggct gaggcgatat cggcgatctc
    41881 ccgatccagc gggctgcgtc cgctgatgac gatgcagtag cgttgggctt tcgcggctgc
    41941 cgcacggcgc gcgccggtca ccatttgatc ttgcggcaac aatccatatc gttcgatggg
    42001 cgccgtggac acggatgatt gcgagcagta gccgcagtct tcctggcagg cgccgctctt
    42061 ggcgttcaag agcatttgca ggcgcaccgt cttaccgaag taccgttcac ggaccttaaa
    42121 ggcggcctgc agaagctcga gcaggttggt gtccggtgta tgtagtacgg tgaggcattc
    42181 ctctcgggtg agtaattcgt cccgcaaggc cttgtcggcc aggatcgtga aatcagtcat
    42241 gcacgctact cctcgaaaaa acaggcaagc cccgctcctt cagcaatgcc tccgtgagca
    42301 aaggatctgt ctgtaacatg aaaaaagggc ggtggaaacc ctacacggtt tcaaacggag
    42361 atgcaatgcc ttgatagggg acggcaggca gccgggcagc ctgtccgtcc tgatcggcac
    42421 cggatttggt gctgtctctc cagggaaggg cgacgtaggt attccagcgg ccgcaccgcc
    42481 ggcaccggcc ggaccattcg gccaactcat ggtggcactg ggtgcattgg tagggcacca
    42541 cgactcgctt tttgaagccc agggctttct tgagctcgcc caccgcttcg tccatgtgtt
    42601 gcttgcgcag gaacagattg gccatgatct tatggtaatc aacgagctgt tcctgcgtgc
    42661 catccagcgt tgaaagcacg tcgtacgctt catcgaccat ttcgagccgg taatacagct
    42721 tgcccaggta gaactggatc acagcattgt gcggatcctg ttgcagagct tcctggtaga
    42781 cacggatgat ttcatccggt tctcccagct ccaggaacag ttcctcgagg cggtgaagga
    42841 tgatgacgct gcgcgtcttg gcgtaaatct tcttgagaat ttcgaccgcg ttcttgattt
    42901 tgccctcacg gaccaagatt tccccgatgc cgatgtaggc cggcagaaag gtgcgatctt
    42961 tcttaatcgc gcctcggaag taccggcggg ccttgtccgg gtgccctcgt tccaagagtt
    43021 ggcggccgac ttcgtacata cagcccaata acagattggc ctcggcgcgt cgctcgcttt
    43081 ccggcaggtt agccttgacc aaccggtgtt gaatctccag cgcgtcgctc catttttcga
    43141 gcctgatttg cagatcgcgc ttgcggatca gggccattag attgtccggc tcgatccgca
    43201 gaatattctg gagtgtctga agtgcctctt catagcgacg ggcgccttca agatctttgg
    43261 ctaattcgag cagcacctcc acatttcgtt cttcaatgcg ataggcctgc tggtggagcc
    43321 ggatggcctc cgtaaagttg ctttcagagc gatagatatt tccgagccag agcagcgaat
    43381 cggtccggtt cggatcaatg accagggccc gctcaaacag actcaccgca tcggctgtac
    43441 gcttggacat gaaggcgtgc gtgccatccc ggtggagcgc gtccactttc tctttacggc
    43501 ggacgaggcg attggtgcgc caattcatga agacgtggga ggtttctttg atcgtcacga
    43561 tcagtgcaac cagcgtggcg cccagggcca tcgagaatag caccaaggag acggggctga
    43621 gctcgaagat cgcgtcggga ctggtccgga cggtgatcgt gcccgggttc agttcgcgga
    43681 aatagctgta gagaaagatg ccgacactga ccaggaagat cgtggagagg agccgaaaca
    43741 tgctagaccc gtttccgggt gcgagcggga cgggccttcg ttcgtgcggg gggagtcacc
    43801 ttcacggcgc gctcttccgg cagcttgacc tgtcctgcgt cgccccacag tcgttcgagg
    43861 gcgtagtgtt cgcgaatatc cttttggaag atgtggacga tgacgtcacc aaagtccatg
    43921 acgacccact tggcagacga cgcgccctcg ataccgagcg gcggatgccc ctgggccttg
    43981 agcacatcgc cgacatggtc cgcgatcgcc cgtgcttgac gctccgactc tccggagccg
    44041 atgactaaat agtcggcgat agaggtcagc ttggcgatat gcaggatcag gacatcggtg
    44101 gctttcttgt ccagaatggc ggccgccacc gcgagagctt tggcttttgt ttcagaaacg
    44161 ctcactgtcc tccctgtata acccctcgcg aagtatatag gattcgacca gggggggcaa
    44221 cagatttgcc agaggacggc catttgcgac acgtgctctg atgtccgacg cagaactctc
    44281 gcagggcggc agccttagaa atgtcacggt ccgcccattt ttcaatggga cgtccgctcg
    44341 ctccagccgc cctgtatcca gagcgagcaa ctcctccttg ggcacttcgg gaaagagagg
    44401 cagcgaggcc acggtcagaa acgttgtggc gggcctggaa attacgacga aatgacacag
    44461 gnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    44521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nctggttgtt tgtgcggagg
    44581 atctccggtc gggatgaaca agacttgatc cagacacagc agacgccgcg ccgactgtgc
    44641 aatcgagagg tggcagcggt gaatcggatt aaaactgccg cccaaaagtc ccagacgcat
    44701 aggaggctac cttcacgcac gattgtgcag gtctcggatg gacaggcccc cgtcgaacga
    44761 cgccctgcat cggcggcgtc tggcggccgc tacaagagca ccaggttgtc ccggtgaatg
    44821 acctcttcat actcttggag accggggatc ttttggatat cggcggtctt gaggcccttg
    44881 atgcgggtca ggatcgtgga ggaaaaatta accaggcctt tggcgcactc tttgccgtca
    44941 ggtccggcgc aggtgaccgg atccccagct tcgaactggc cggtgatgtc gcgaatgcct
    45001 gaggccagaa ggcttttgcc gtttcgcacc agtgcatcca ccgcgccttg atccaattgc
    45061 acatgtccgc ggggccgcaa cgtgaatgca atccaatgtt tgcggctgtt catgcgtcgc
    45121 tcccggccga gaaacaggct gccccccggt tgcccggaca gcacatccgg aagcagaccc
    45181 gtgcgagtcc cgttcaggat caaggtcgcg accccgtatt cgcccacttt cttagcggcg
    45241 cggaccttcg tggccatgcc gccggttcct tcgaaggtgg aggacatgcc cgcccgttgt
    45301 tcaatgtcgg ccgtgatctc ctgaatcagg ggaatcaagg tggcttgtaa atctttgcga
    45361 gggtcggcgg tgaacagtcc atccacgtct gacagaatga tcagcaggtc ggcgtctacg
    45421 aggtgggcga cctgtgctgc cagcgtatcg ttgtctccta cgcggatctc ttcgacggca
    45481 accgtatcgt tctcattgat gatggggatg acgccgaatt tgatcagcgt ggtgagggtg
    45541 tgccgggcgt tcaaaaaccg gcggcgatcc gcgaggtctt catgggtcag cagcacttgg
    45601 gccacgcgaa gcgagaggcg ctcgaacgcc ttctcgtagg cccacatcag caggctctga
    45661 ccgaccgccg cggccgcctg tttgaccggc aggcttttgg ggtactcacg tagctccagt
    45721 tttttgatgc ccgagacgac ggcaccggac gagacgacca gcacttctcg cccctgtgcg
    45781 cgcacgtggg caatttcgga ggcgagtcgt tcgatgcgct cggtgctcag gccggattcg
    45841 cgtgaggcga ccagactgct tccgatcttg atgacgacac gtctggcttg ctttaggagt
    45901 tcgtctcgca cggggtcttc cggagcagtt ccacctgttg gcccatgtag agtatgcact
    45961 cgtccagacc ttctcgcgtg gctgccgaaa tcgcaaaaaa tggaatcttg cgccgctggc
    46021 aatatttccg aagttgttcg aggcgctcgc cttcgccttt gatgtcgagc ttcgtgccta
    46081 ctacggcaaa gggacgcgcg gcgagtgcct catcgtaggc ggagagttca tgacgcatga
    46141 ccttgaggct cgccactggc tcctccgtgg cccactctga aatatcgatg acatggatca
    46201 gcaggctggt gcgctcgatg tgccggagga actgaaagcc gaggcctttc ccttcatggg
    46261 cgccttcaat cagtccggga atgtcggcaa tgacgaagct gtgttcgccc gtcgagcgga
    46321 cgacacccag gttcggtgta agggttgtaa agggatagtc agcgatcttg ggacgcgccg
    46381 cagagacggc ggcgatgagc gtcgattttc cggcgttcgg gtagccgact aatccgacat
    46441 ccgcgaggag tttcaagtcg agacgcagga ggcgttcttc gcccggtgtg cccggctcga
    46501 actgagtcgg aacgcggttg gttgaggtgg cgaatcgcga gttgccgcgg cctcccagtc
    46561 ctcccttggc gatgacgcaa ctctcgccat ccgcggtcag gtccgccaaa agttcctgcg
    46621 tatttgcatc gagcacgatc gtgccgaccg ggacaggtat ccgcacgtct gcgccgcgtc
    46681 gaccctggca gttgctgccg ccgccgacct cgccgttttc tgcttcgtaa tgtttttggt
    46741 atcgaagatc cagcagggtg ctgaggcgag tcgtggcctc gacaatgacg ctgcctccgt
    46801 ccccgccgtc cccgccgtcg gggccgccgc gcgggacaaa cttttcccga cggaagctgc
    46861 aggctccgtt gccgccgtgc ccggccttta ccaggatttg gacttgatcg acaaatgtag
    46921 acatcgcagc gagcccccac ccggcgtcat ttattcagga atcacagtat agcgtatccg
    46981 ccggctcatg ggggatgctg cgtaagcgaa ggggcgctgt tccgcggaac aagactgaag
    47041 ctaaggaggg atcaggcctt cgcggtaact ggatagacgc tgaccttttg ccgtccgcgg
    47101 ccaccttcga actttacgac accggacacg taggcataga gggtgtgatc gcgtccaagg
    47161 ccgacgttga ggccggggaa gaatttcgtt ccccgttggc gcacaatgat ggagccggcc
    47221 ttgatggtct ctccgccgta ggcttttacg ccgaggtatt gtgggttact gtcacggccg
    47281 tttcttgtcg aaccgccgcc tttatttgtt gccatggcaa actccccttc gagtcgttac
    47341 ttcgatgcga tctcagtgac ccgcagctgc gtaaagccct gccggtggcc tctggttcgg
    47401 cgataatttt tgcgacgttg cttcttgaaa accgtgatgg acctggtgcg tccctggcgg
    47461 atgatttccg cggtgactcg cgcgccggca acgaccggct ggccgatgac cagtccactg
    47521 tcgccattca gcaatcgaac cttgtcgatc tgcacggaat ggccgacatc gcccgggagc
    47581 gactccactt ggagtacggt ccctgtttcc actcgatact gttttccacc tgtttcgata
    47641 atagcgtaca tgtgcgtcct tctcctcgtc agcagaacgt gggtgtttat cacagcctcg
    47701 gcgagagtgt caagaattag tcctggtgtt gcgcgaaacc attccttgtc gtgcggcacg
    47761 aagaagtgga gtcgtacggt cggaggcaac aaaactacgg cccgggagcg tggcggctgt
    47821 tatcttgacg ctcatcgcga gccgctggta ttatcccgcg catgttacaa accagcgaaa
    47881 aaatatggat ggatggcaag tttgtggcgt gggccgatgc acaggttcat gtgttgaccc
    47941 actcacttca ttatggatta gcggcctttg aaggcatccg ctgctataaa ggcaccagcg
    48001 ggtcggccat tttcaggcta cccgagcatg tggaccgcct atttgagtcg gcgcacatcg
    48061 gtctgatcga gattccctat gaccgaaagc aaatgaccga cgccattatc gaaacggtca
    48121 gagtcaatcg gctagaggct tgctacattc gcccgctcgt gtatatcggc tatggcgcca
    48181 tgggactgta tccgggagaa aatcccatca aggtcagtat cgctgcctgg aaatggggga
    48241 cttatctggg ggatgaggcg ctgcagaagg gcattcgtgc cagagtgtct tcatttacac
    48301 gacaccatgt gaacgtgtcc atgacgcgtg gcaaaatttc cggctactac gtgaactcga
    48361 ttctcgccaa gcgggaggtc aaagccgacg ggtatgatga agcgattatg ctcgatcccg
    48421 aaggttatgt ggctgagggg acgggagaaa atgtcttcat cgtgcgacgc ggtgtgttga
    48481 agacgactcc gttaacctcg attctggagg ggattacgcg caattccatc attcagctgg
    48541 cgaaagagcg caacattccc gtggttgagg aacgattcac ccgtgatgaa atgtatgtgg
    48601 ccgaggaagt ttttgtgacg gggacggctg cagaactcac gccggtgacc gaaattgatc
    48661 agcggcgtat cgggaccgga aaaccaggga cgatcacgca gaccttacag aaagcgtttt
    48721 ttgatgtcgt gcgcgggacc gatgcggctc acagtcagtg gctgactccc gtttagcaag
    48781 tctcggtaac ctcacctgat ctcttagtcg agcattcatc acattgatgt gctgtggcgc
    48841 gaacgctgca ctggccttcg aactcctgca ctcagagtgc ttctccattc cactactagc
    48901 gtagtgcccg cgcgagcaat cataggggtc tcacttttta gtcagagcga gaggaaacga
    48961 ttcggctcgt tgatcgaaac ctgcgtggaa tcgaaggcta gctggaacag taggtcttag
    49021 tgggagctat cggtggagga atgcgagtct ttcgccggcg gcgtcgcggt ttctgccggt
    49081 gtcgtactgg gagtggttgc cgcaggtttc ttgttcagat caatgaccgt cgaggaaaag
    49141 tttcgatcct tcgcaagaat ggccagagac aatgacgtga acatgaagac aaacgcggtg
    49201 atgaccgtga acttgctcaa aaagttggcg ggccctcggc tgccgaacac ggtttggctg
    49261 gatccaccaa aggccgctcc gatttcagcg cccttaccgg attgcagcag aatggctcca
    49321 atcataagga ggcagacgat gacatgaatg atgatgagca atgtgtacat gtttgagtct
    49381 ttaggccgtg gtaggttttg acccgatggc gactttggcg agtgtagcaa aagagaccgg
    49441 atctaaacaa gccccgccga ctaatgcgcc gtcgatttct tcggaagcca gaaattcggc
    49501 gatattgtgc ggagtgacgc tgcctccata cagaatccga acacgcgccc ccgcttcagc
    49561 tccgctcagt tcattgatgg tttggcggat caatcgatgg accggcaccg cctgttccgg
    49621 cgatgcggct cgccccgttc caatggccca cactggttca taggcgatga ccatcgactc
    49681 aagatgttgc ccctcgattc cagccagtcc tgcgcgaacc tgtcgttgga ttacttggtc
    49741 tgtttgattg gtatcgcgat cgtgaagtgt ttcgcccaca cagagaaccg gttggatgcc
    49801 gttacgcaaa gcagccagaa ccttcttgtt ggtccagctg tcttgctcgc cgaagtactg
    49861 gcggcgttcc gaatggccca ccaggacaaa ttgacagccg agatccttca gcatggctcc
    49921 cgacacttct cccgtgaagg cccccttatc ttcccaatac aggtcctgtg cgccaagcag
    49981 aaaatccggt gaggaaccga gcgcctcatg ggctgcatgc agcgcggtaa agggcggtgc
    50041 aaaaccgacc tggattcctt cagacctagg caactcctgg gtgaggcgac gaacgaacgc
    50101 ccccgcttcg gtggcggtct tattcatttt ccagttaccg atgaggaagc gggttctcac
    50161 gaagcctcta gtgggagaat ggagaaaggg tgtcgttacg ctgcacgatt ggggagggcg
    50221 gcaagtcccg gtaaggtttt cccttcgagc agctccaggg ctgcgccacc accggtcgag
    50281 ataaacgaaa tgctttcgga ctctccggcg cggtgaatag ccagggctgt ttcgcctcct
    50341 ccgacaatgg tcagcgcgta ggcgttggcc acggagtgag ccatggcgag ggtgcctctc
    50401 gcgaaggcgt cgacttcgaa catgcccatg ggaccattcc acagaatggt tttcgcatcc
    50461 tgcacggctt ccgagaacaa ttttacggag gcgggaccga tgtccaggcc ataccatccc
    50521 ttgggaattt cctgaaccgg aacgattttc gtttcggctc cgggctcccg gccggccgca
    50581 acgacgcagt ccacgggaag atagaatttg acgccactgg caaaggcgtg gtcctgcacc
    50641 cctttggcaa agtcgagcat gtcgttttca acgagtgact ggccgatctc aagacccatg
    50701 gctttgagga acgtgaacgc catgcctccg ccgatgatga ccttgtcgac tttcttgccg
    50761 agattctcga tcacgccgat ttttccggat accttggcgc cgcctaagat ggctacgaac
    50821 ggacgcaccg gattttcgac ggctccctcc aggtattcga tttctttctt aaggagatac
    50881 ccggctgccg cttcgggaat atatttggtg atgccgaccg tggatgcatg ggctcgatgg
    50941 gcggcaccga acgcgtcatt gatatacaca tcagcgagtg cggccagcgc cttggagaat
    51001 ccttcgtcgt tcttttcttc ttcgggatga aagcggaggt tttccaataa catcacatcg
    51061 ccaggctgca tcttggcaac caggccttca acggcggagc cgatgcaatc cggcgcaaaa
    51121 atcacttctt tgccgagcag gcgctggagg cgtttggcca ctggagccag gctgaacttc
    51181 ggatcgaatt tgcctttcgg acggccgagg tgggagcaca aaatgacctt ggcgccctcg
    51241 tcgacggcac gattgatggt gggaagggtc gatcgaatcc tcgtgtcgtc ggtgatctgc
    51301 aaggaatcat caaggggtac gttgtagtcg gcgcgaataa tgacgcgctt tccgcgaagt
    51361 tgcaggtcct cgataatccg tttgcgaata ttcatggcag atcctcactc ctcctctggt
    51421 gtgtccgcgc cgggcgctgg cagctccggc cggtgctgca cgtcagaaaa gcgtgtcgtg
    51481 cgtgacgcct gttacgccga ttttgcaaca atatacttga tcaggtcccg cacgcggcag
    51541 gaatagcccc actcgttatc gtaccaagcg gtgactttga cgagccgttt atcgatgacg
    51601 gcggtcagcg gagcgtcgac aatggcagag tgggcatcat ccttgaggtc gatggagacg
    51661 atgggtgctt ccgagtaggc cagcacattt ttcatgggcc cttcagcagc cttcttgaat
    51721 gcggcattta cgccggccac atcgcaatcc ttctccgttt cgacggtgag gtccaccagc
    51781 gagacattgg gggtgggaac gcgaatggcc aatccgtcga gctttccttt cagttgcgga
    51841 ataaccaggt gcagggcctt cgccgctccg gtgctggtgg gaatcatcga catccctgca
    51901 gcacgcgccc gccgcaaatc tttgtggggc agatcgagga gctgctggtc gttcgtgtaa
    51961 gagtggatcg tcgtcatgac gccgtgttta atgccgaagt tttccaacaa gacttttgcc
    52021 accggggcca gacagttcgt ggtgcaggag gcattggaga cgatatggtg agctttggcg
    52081 tcgaagacct gctcatttac tccaaggacc accgtggcat caggatcttt cgcgggggcg
    52141 gaaatgatga ccgttttagc tccggccgac aggtgctttc ccgcgccttc gcggtcggta
    52201 aaatggccgg tcgattcgac gacgatatcc acgccgagag ctttccatgg gagctctttg
    52261 gggtcccgga ccgcgagaac cttgatcgcg cggccgtcaa tgatgagctg gtcgtctttg
    52321 gcctcgacgg aagcgtccag cgtgccatga accgagtcat acttgagcaa ataggccaat
    52381 gttttggcat cggtgagatc gttgatggcg acaaattcga ggctgggatc tcccagggaa
    52441 gcgcgaagaa cgttgcggcc gatgcgtccg aatccattga tgccgatgcg tgtggtcatg
    52501 gggctaaatc ctcaagaatt aaacgggttg aacagagtaa atctggggcg atagtactga
    52561 ccgactttct gcgtgtcaag catacaaaaa gagggaaggc cggtggatat tggcgaaagg
    52621 gcctcaggga aatgatgggg tgttggccgt cttgttgtgg acgtatgggg tccggtagag
    52681 tctcatgcct gagcgttcat cgagatgggg cgtgatgcaa tctgaaaagc tgcagttcga
    52741 agcgtgcaag gtcttggagt gggccaaact gttggatctg ttggccggct acgcccagtc
    52801 ggaggttggg gcggagcaat gccggtccat ggaattggag cgggacgtgg cgcaggctcg
    52861 gctgcgccag gaagaaacct ccgacatgtt gcgcctgcgt gccagcgtcg acccttttcc
    52921 tgtcctgcga ttccctgacg tgacggagtg gttgaagcga gtggtgaaag gcgcctgttt
    52981 ggaggcgcat gagctacgag acatcgcgct ggtgttggaa ttggtcgtgg atgtccagcg
    53041 atacctgctg cgtcatcagt ccgatgctcc gacggtcggc gccatggccg agcagttggg
    53101 accggtgatg gaataccgcc ggctaacggt cgcgctaaac ggggccatcg accccgatgg
    53161 gtccattcgt gaatcagcca gccctgagtt acaccggttg atccaacggg ccaacgattt
    53221 caaacaacag atgcgacatc ggctcgagca aattctgcat tcgcggcgct atgaagaagt
    53281 gttgcaagaa cgatattttg cacagcggga agggcgttat gtggtgccga tcaaggccga
    53341 gatgcaaggc cgcatgcccg gtatcgtgca cgacgtctca tccagcggtg ccacactgtt
    53401 tctggagcct cgggaactgg tggatctcaa taactccatc aaggtcgtcg atctggatat
    53461 cgaacgggag gtgcgcagga ttcttcggga actctcggcg ctggtggccc ctcatcaacc
    53521 ggcgctcgcc ggcagtgtga ctctgctcgg tcggctggat gcgatttcgg caaaggcagg
    53581 cctgagtcaa cgtctgcaag gttccccgcc gcggctcaat gaccagggac gcattctcct
    53641 tacgcaggcg cggcacccgt ttctggtggt gagcaaagat caggtcgtgt cgaatgatct
    53701 cgcgttcgat gaaaccgtac gggtactgat catttccggc ccgaatacgg gcgggaagac
    53761 ggtcatcttg aaattactgg gtctgttctc tctgatggtc cgctgcgggc tgcaccttcc
    53821 ctgtgccccc gagtcggaga tggcgatctt tccgtctgtg tatgcagaca tcggggatgc
    53881 gcaagatctg gcgcgcgacc tgtccagttt ttctgcccac atcacacaaa tggtgcagtt
    53941 actgaacgaa gtgtctgatg gagcggggag cgaacacgac agggagccgg tgcctcccgg
    54001 acgagcgctg gtgttgttag atgagccggt cacctccacc gatccggccg aaggcgcagc
    54061 gctcgcgagt gcactcctct gtcggctcgc tgcggccggc gtgaaagtgg tggccaccac
    54121 acactacagt ctcttgaaag gtctggccca ggacaggccg ggcttcgcca atgccagtgt
    54181 ggaatttaat ctcgacacgc tttcgccgac ctaccgtctc attcaagggc aaccaggcgg
    54241 ctcggccgca atcgaaattg ccgggcggct cgggatggat cagtcgctgc tggaggatgc
    54301 ccgcgcacgg ctgcagggag acaaccggtt gctggagaca ctgttgagcg atttgcagga
    54361 caaacaacga cgactcaatg acgacctggt ggcggccacg gcggccaggc agggtgctga
    54421 gcaggcttct cgcgaggcgc aggagttgct cacgttcctg caggaatccg agcgggatga
    54481 gcggcagggg ttgaagaaaa agttgtctca ggagtttcaa cgggcccgcg ccgcggtgca
    54541 ggcgacgatg gacgatctca agcgcgatca aaagctgctc aaggccaagg aggccaaagc
    54601 ccggctggtc gaattggaag agtcagtccg gcgagaggcc ggagactccg aagaaccgat
    54661 tccgattgat cagctgacca tcggagatgc ggtcgaagtg atcgggctgg ggatgacagg
    54721 tacgttgctg gaaaatcccc agggcaaaaa acgcgtgcgt ctgaaagtcg gcgagggcga
    54781 aatcctggcc aatgtggcga gcctggcggg agtctccaag gctcgccagc cacaagcgcc
    54841 agccgcggtc aaaacgagcg ttgtctcacc gaggcgaacc agccagacct tggcgcctga
    54901 agacatccag gagacgctgg atgtccgtgg tcaggcagcc gacgatgcgt tggatgtggt
    54961 ggtcgccggt ctcgatcgcg ccattctcgg cggtagcccg ttcgtacgca tcatccatgg
    55021 gcacgggacc ggccggttga gaagcgcctt gcgagactac ctgaaagact caccgtacgt
    55081 ggtggcgttt cgagggggcg atcgcgcaga gggaggcgac ggcgtcacga ttgtgcagct
    55141 gcggtgagat cccgccgaga cccgctcaaa aacacccgta gcccctttcg ctctttctcg
    55201 ttctccagta cgatagcccg cctgtgacat gatcgggggc ggacctgtct tgttcatgcc
    55261 attttctcca cgaaccaaaa aaatcctttc agcgattgcc gtcggagttg cggtctatgc
    55321 cctggtgacc gggctccgca tgacgcgatg gttcgaggtg gtggaactca aggccttcga
    55381 ccatctcgtc cggcgctatg ccgatcctgc caaggccgat tcaagtctcg tgctgctggc
    55441 catcgatgaa tccagcctgg aagcgttcgg gcgctggccc tggccgcgtg accggtacgg
    55501 gtatgtcgtg cggtatctca aacgggctgg agccaaggcg gtcgtcttcg atgtgatgtt
    55561 tttcgaaccg gacgataatg ccgaagaatt cgatcaatcc ttcgccgacg atgtgaaggc
    55621 cgcggggaat gtcttcctgc cgatgttgtt tcaatccgaa gcggcgccgg ttccagccgg
    55681 gctgcaggac catgccaccg taaaggccga acgatcggac tcaggaccgg tacaggctgc
    55741 agcgcacccg ggtgtgaaat tgcccattcc tgtgttggcg caacaggcgc gtgggttggg
    55801 cgtcatcaat ctgtctgccg acgccgacgg gccgacaagg cgtcttcccc tgctggggca
    55861 ggtgcaagga aatctggtgc cgcatctctc gttggcggta gcccgatacg tgttaggcgg
    55921 tagcgagctc gcgatgcggg acgaccgctt gcagatcggc gacagcagcg ttcctctgga
    55981 tgcagacggc aatctgttga tcgaatggca tgggtccctg gagcagacct accacgccag
    56041 gagatactcg atcggccggg tcttgcaggc cttcgcgcag caagaaaaag gggaacgtcc
    56101 ggatctggat gcgtccctgt tcaaagacaa gatcgtattt atcgccggga cggcggcagg
    56161 gttatatgat ctgcgagtga caccgttttc ctccgccacg cctggcgtgc tcatccacat
    56221 ggcggcgctg gacaacctgc tgcatgggca ggggcttcaa gcggcgccgt cctggttttc
    56281 tctttccatc cttctgctgc tttgccttgt ctcagccggt gccttcatgt tgttcccgtc
    56341 ctatccggtc aaattcggcg tcacgatcgg cctcgctctg gcctactatg ggttggtggc
    56401 gcatgccttc gcggggcatg agcggtggct ggatctggtg tttccggaag tcgccctcgc
    56461 cttaacgttc ggcacggccg cgacggttga gtacgtcacc gaaggcaagc agcgccggct
    56521 tatgcgggcc gcgttcgaca aatacatgtc gtctgaagtg gtcgaagaaa tcatgcggaa
    56581 tcccgcggcc attaagcttg gtggcgagaa gaaggagatt tcgattctct tctccgacat
    56641 cgccggtttc acgaccatct ccgagaaaat gtcgccggag gatcttgtcg cattgctgaa
    56701 ccggtacttg tcggcgatga cgaccatcat caagacgacg catcgcggca atgtgaacaa
    56761 gtatctcggc gatggaatca tggcgctctt cggcgcgccc ctgaacgatc cccaacatgc
    56821 gtcgctggcc tgttatgccg cgctggattg ccaggtcgaa ttggcccggc ttcgtcaggt
    56881 ctggaagcag gagggacttc cagagatcgg cgcccgcatc ggtattaatt ccggggcctg
    56941 catcgtcggc aacatgggat cggaggagcg catggagtac acggtgaccg gggacagcgt
    57001 gaacctggcc tcacgcttgg agggcgccag caaatattac gacaccttga ttttgatcgg
    57061 ccagcgaacg gccgaattgg ccaagaacga cgttgaagtg cgagagatcg atctgctacg
    57121 agtgaagggc aaaaaagacc cggtcgtcgt ctttgagttg ctggcccgca aggggcaagt
    57181 ggaggaaaag aagcggcgcg tcatcgacgt ctatttggaa ggattggcgg cctataaagt
    57241 gaggaacttc tcgatcgcct gcgccaaatt ttctgaagcg gtgaccttgg acccatcgga
    57301 cggtccgtcg cgggtgtatc tcgaccgcgc gactaattat tgccagacgc ctccgtcagc
    57361 ggattgggac ggggtctatg aaatgacatc aaagtgagcg gcggtgttga aggggaggaa
    57421 gctgtgatat caccacgagt gcttcgcgtt gtcctgatcg ttctgtggat cggtctcctg
    57481 gtctggagcg gagaaggccg ggccgaaacc gtctacgttc aagccaagac cgcacaactg
    57541 cgcgccggca aaacgtcgtt ggatgctgtc gtcgggaacg tcaagttcgg cgacgcactg
    57601 gaggtggtgg ggcgtgacgg cagttgggtg gaggtcaaga catccgctgg cgcgaaagga
    57661 tggatcttcg ccaacaaaac ctcgtcgtcc aaaccgtccg gcaccaatga taccctggcc
    57721 aaactcgggc agagtatgcg ggggagcgat gcgtcggcca cgacggcgtc ggcaggcgcc
    57781 agaggcctgg ataaggcttc cgaaggctat gccaatcgcg ccggcgtatc cgcgcgcgat
    57841 cgtgacgccg tggaccggat gaccgcgtat cagattcctg atcaggaggt cgaagaattt
    57901 ttgcgagaag gaggcctcgg tgaatatgcg aagtaatcat ggcctgacag cgacgatcat
    57961 cgccctctca ctgatggtgg ccggttgcgc ggaagtgcag cgcgccagtg aagatatcgc
    58021 gcggcaatcc ggtaatccgc ggctggccgg tgccattcac ggagtcggca atgtggtggg
    58081 gagtttgttc ccgatcgggt acgaggaaga gtcgtcgatc ggccaggcga tggctttgca
    58141 ggtcgtcgca cggtatggcg gagtcgtgga tcagccagag ctcgtccggt atgtgaatct
    58201 ggtgggacgg gccgtcgcga acacgtctga ccggccggat attccgtatc gggtggcgat
    58261 tctggaacat gaatccatca atgcgtttgc cgcgccggcc ggctacatct ttgtgacgcg
    58321 tggtctgctt aagcaggtcc gcaatgaagc ggaattggct gcggtcctgg gccatgaaat
    58381 cgcccacgtc agccaaaagc atattctcga tgtcattcaa cgcagcaaac gcctggccgg
    58441 ggtaaccgaa gccggcctgt cctacgcgac gagcaatcca gcggcgttca agaccgtgat
    58501 cgacggcgcg gtcaagaagt tgctcgatga aggcctggat caggacaagg aaacggaagc
    58561 cgatacgatc ggcgaagtgt ttgcgacgcg ggtcggctac gatgcggaag cctatgtgaa
    58621 cttgctgacg cgcctacgag acctcaaggg tgacgaccgg gctttgttta agacccatcc
    58681 caacttttca gcgcgtatcg aggccgtgca gaaaacgatt cagagcaaac atctcgtggc
    58741 caccggcgtc ttattgccgg agcggtttgc tcgcatgacc aagcgcgtgt agcgcaagat
    58801 tgtgaaatgg gcagccagcg gcgttctcgt gtcgctcagg gactgaacgt accgtgaaga
    58861 tacgcctcgc ctcttcgctc gctgcggcct tgctggacag cccatttgaa catcttgcga
    58921 ggcggctgaa aaaagtcctc cagctttctt ctcgcatcat tcagactctc aacgtagcca
    58981 gccagtacac ctcgggtctt cacttgctac ggccccgctt gagagtctgt ttgagccgcc
    59041 tctcaggctg cttcgattgg tcgtcagcgc tcttctcgct tcccggatga gccatcccta
    59101 ggtcgccgag cgaaaccgca gcgtacacgt ggtgcctttt ccttggttag tggtcacgat
    59161 caaggtcccg ccgttgtctt ccacgagccg tttgacgttg gtgag
//
LOCUS       DAOQPD010000016        58217 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_196_length_58217_cov_23.230700, whole genome shotgun sequence.
ACCESSION   DAOQPD010000016 DAOQPD010000000
VERSION     DAOQPD010000016.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 58217)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 58217)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58217
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_196_length_58217_cov_23.230700"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1778)
                     /locus_tag="PK063_05790"
     CDS             complement(<1..1778)
                     /locus_tag="PK063_05790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4105 domain-containing protein"
                     /protein_id="HMZ96591.1"
                     /translation="MSQLLQRAHQAKLADEREWHLLLHYRANLFGGFTSEQDEPGFFL
                     SPDGKTDPEAELDSTLTQFFSPDLVGRSKQPAQCAFVARYAWLHERLAFDPGQLPVMR
                     CDRFERWFEEFHARSVTLVFPSAFMNNPASMFGHTLLRIDQEGQTPHTRILAYTINFA
                     ADVPKDEGLAYPVRGIFGGYRGYFSTIPYYLKVQEYRDMENRDIWEYRLNFDAPQIRR
                     LLMHAWELGNASFDYFFFKENCSYHLLSLLEYADPSLRLTDKFRFWTIPADTVRLLAD
                     QPGLVTDTAFRPSRVTLIRRKREQLTVAEHGLVQRLVRDAAVAQSDDVRSLPLSRQAF
                     VLDVASDYVRYTGERDESQATAARDHNRQLLTARSLLRIPSEELSILPFATQPELGHK
                     TSRASLGGGWRNNDSFEEVSVRTAYHDLLDPEPGYTPDAQIEIGSISLRHYNRADQAR
                     IERATLLNVVSLSPIDSLFRAPSWKLNVGMQTIRHGECQLCSNWSMNGGIGASAETHM
                     LRREVFFAFAEVEGNYSRAYEERHRVGGGASAGFYADLAERWRVLATATYLRYALGDR
                     SDDVRWSVGQRYTLAQNWALRLDYNHR"
     gene            complement(1918..2427)
                     /locus_tag="PK063_05795"
     CDS             complement(1918..2427)
                     /locus_tag="PK063_05795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3015 domain-containing protein"
                     /protein_id="HMZ96592.1"
                     /translation="MLRQIIVALGVVAVASQAGLALAANPDTGPGCGLGKLAWADYKN
                     QKNIAPQVMMATTNGTFGSGTFGISSGTSGCTNDGQVMADQKTTMFALLNFENLTQEM
                     AQGKGEHLASLATLMGVPAEQHAAFFALTQERYTALVQDGETSSVALVKTLNDAVSKS
                     PVLAQAVSR"
     gene            complement(2550..3035)
                     /locus_tag="PK063_05800"
     CDS             complement(2550..3035)
                     /locus_tag="PK063_05800"
                     /inference="COORDINATES: protein motif:HMM:TIGR00040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HMZ96593.1"
                     /translation="MRIGVISDTHGLFDPSITRHFAGVEHILHAGDIGPRDVLAQLER
                     IAPVTAVSGNVDGFDASGIPVEQTIELAGHRIAVYHRLYEGGRLTGDGIDLLERIRPT
                     VCVYGHTHQPKAEWRDGVLLFNPGSAGPKRFRLPRALGVLLFQNGSIETRHIMLADRA
                     E"
     gene            complement(3049..4182)
                     /locus_tag="PK063_05805"
     CDS             complement(3049..4182)
                     /locus_tag="PK063_05805"
                     /inference="COORDINATES: protein motif:HMM:NF013594.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HMZ96594.1"
                     /translation="MNATPNALCFGEGLPGAGVPCTVMLVEEGLRVSPMGESALAEQV
                     VTFADMAVEAGGLDHDQLVVSWGTGPSVWTLYVKDPALIVAFRRAAPPQLTAHLERAA
                     EQVRRARHSHRLLWGSVLGVVFGLGLLLWFGTDLMVEWAVARIPIEWEQKLGETVYQD
                     FLSKETVLKEGPAVSAVQEMTQRLTEKIPNNPYKFQISVVQSPVVNAFALPGGYVVVF
                     TGLMTKAESGEEVAGVLSHELNHVLQRHGMERMVKMLGLSAVVGILLGDQQGLTGLAK
                     QVGMELVTLKFGRAQETEADVTGIRLLSDARIAPDGMIRFFERLSEKDKERVEVFSTH
                     PMSAARAALLKAELAALPKRTPEPFTFQWKTIQDSLAVSEPKK"
     gene            complement(4357..5040)
                     /locus_tag="PK063_05810"
     CDS             complement(4357..5040)
                     /locus_tag="PK063_05810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HMZ96595.1"
                     /translation="MKCEILYPGAFPMVRVYLDASETVKAESGAMVAASPTIDIESKM
                     EGGFLGALSRKMLSGEKFFFQTLRASRGAGEVLLAPTVPGEIVLLELDGVNEYMVQKD
                     GFLAGAEGVKIESKMQSLTRGLLGGEGFFILKIGGTGQLVLNSFGAIHKIELKPNEEY
                     IVDNSHLVAWSSTTTYNIEKASSGWIASLTSGEGLVCRFRGPGVVYIQSRNPGSFGNW
                     IRQFIPVSE"
     gene            5280..5615
                     /locus_tag="PK063_05815"
     CDS             5280..5615
                     /locus_tag="PK063_05815"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96596.1"
                     /translation="MKRVVIEELTPGMILAKPVTNNTGLVVLPPGAELDEATLSRLQR
                     LGLTSVYVEGDAGDASGKTLAELEAELDHRFRLVSDDPIQCQIREAIRQQLRTTHGVA
                     DHQEAPPAT"
     gene            5612..6448
                     /locus_tag="PK063_05820"
     CDS             5612..6448
                     /locus_tag="PK063_05820"
                     /inference="COORDINATES: protein motif:HMM:NF020252.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDOD domain-containing protein"
                     /protein_id="HMZ96597.1"
                     /translation="MKPSANVDLRRRIEQVGELPTLPHVVQKLASMIGRPNVSAEEIG
                     ALIEKDQVLSAKVLRLANSPFYGFPSRIASVAHAVVVLGLSVVKGLTLCATAFDMMKN
                     AGMNDLWRHSLGVAITAHILGAKAGMKNPEEVFVGGLLHDIGKVVLYVKWPDVGQQIT
                     AARKDGSRSLMETEQELFAVTHADVGGWLATAWHLPTTLREPILHHHMPTAAQDAKLQ
                     TAIVHVADVLVKGLACGNPGDDLIPPLSRQAWDLVGLDAQSLAQSLAQAAEEFQTIDD
                     YL"
     gene            6445..7410
                     /locus_tag="PK063_05825"
     CDS             6445..7410
                     /locus_tag="PK063_05825"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: protein motif:HMM:NF013180.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HMZ96598.1"
                     /translation="MSGSPSNRRILLLHHDPVEIERLTAGLSRAGFSVVVADAGRLAL
                     HELVHDPPCLVLAAEGTNGRSADTLAKELRADPFLGRLPVIILIRDSRVNDVDWAALG
                     VDDYIAVPYRPEEVPQRVRLCLSRLERSLDANPLTRLPGNSTILHETTARIESGAPFA
                     LAYLDLDNFKSFNDRYGYARGDEVLVVTCRILTTVVSELAGTDGFVGHVGGDDFVFMS
                     APATIEAICQTLIKRFDLVIPDFYDPDDRGKGFIDSVDRRGNHERFSLMSLSIAVVTN
                     EHRAITHPGDVSKIASELKKIAKSQPGSVYVKDHRKAETTDARTT"
     gene            complement(7441..7947)
                     /locus_tag="PK063_05830"
     CDS             complement(7441..7947)
                     /locus_tag="PK063_05830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3106 domain-containing protein"
                     /protein_id="HMZ96599.1"
                     /translation="MNVLLVGIMAVFIALSPAWAQGDQTGVPWSQLSPGEQQLLQRFS
                     DNWDQLPPRKQQRLRNGARQWGTMTPEERQEAKQRFKEWRSLPPEQRQQLRERYQQFR
                     QLPPERRESVRDARRWFRSLPPEQRKELREKFQTMSPEERRAYRRELRRQYGGSGGGQ
                     APAGVPGQ"
     gene            complement(8248..8604)
                     /locus_tag="PK063_05835"
     CDS             complement(8248..8604)
                     /locus_tag="PK063_05835"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96600.1"
                     /translation="MNERSDEQPDPLSAAAKRLLDHRLQELDQKTVLALQRARVNAVS
                     RSSARRPWLQWAGGVALASMAALAVTMWLWQANGANHSHLLLEDLELMQSPENLELSE
                     DLEFYDWLADGTATTG"
     gene            complement(8601..9152)
                     /locus_tag="PK063_05840"
     CDS             complement(8601..9152)
                     /locus_tag="PK063_05840"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HMZ96601.1"
                     /translation="MASLDQTQALDRFLAGIERRAFRMAHIATGNADEALDLVQDAML
                     KLAEKYARRPEEEWGALFHCILQSRIRDWYRRERVRNRLREFFRGAQDDEDAEDPLEQ
                     IPDSSTPAPDGEVQRKRACAELEVALRALPLRQQQAFLLRIWEELDVAQTARAMGCSE
                     GSVKTHLFRALQVLRQRLGEHWP"
     gene            complement(9565..>11913)
                     /locus_tag="PK063_05845"
     CDS             complement(9565..>11913)
                     /locus_tag="PK063_05845"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96602.1"
                     /translation="PVKAEPITEFTLAGTPAESIETVLEAAPQVEDSLELVGAPEAMM
                     PSGSAPVDEIVEPIPLSSVEEQTVSLAEPIALEAQVEPPAEPSSEESEPAPVLALEPA
                     AKPDEHVVVDSVVTAAEVSLTELTEVPTASAEDAPLVAPHELSTVVPAEESSELVQIP
                     QALEAVQTDQPVDMAASPVPALEPEVPAPAVSAPAEVPASDGLHILWEDASSAPTPKP
                     STGNMLTRWLKKPAEPVAPEVSAVPPATPVPAEPVVPVASQAVEESVPVAVVMEQPYE
                     HIEQAPAAVVEEPTHRPTRIQSAGGGVWSRVAEAAASLVGAGVSTTRSLVVLVLALVG
                     LVLFVVGGTIAAVALTWLILEEQPNAAYRTMTSVPQQTLQDSSKNGYLLLLGLGAAAS
                     QDPVQVGLDRRIEGADRAFTHTCLTGEGYSPDERQSASADAAGKWMKAADPALQMQMD
                     VSGAKTWLSQAEVGLSRYRQWLNKPFEDVGYGQSISPNCGLILQTHRLYLADGFAQDV
                     DTGFARLETDLTAWRTVLGQAKSLPVKMLASAAMNDDAMIMDGLLQRPDLDERYVSRM
                     AKLAKPLEPSEQSLRWPMQSQFVLATKTLDEAVSQNRAETRPFYGAIAAALPLPKQRR
                     FNAYAEYYDAAGKAAADGRYTDLPKLSQFVRVAPYSVSDMVMNPIEGLVGVDSMPTWE
                     TYAGRVLETDARLRLVSLQAWLRRTPPEQDLLTRLAKAGQGLYDPFTGLPMLVNMKKG
                     VLYSVGPDLKDNEAHERLDLVAQIPSVAWAGGKKLADTGKAK"
     assembly_gap    11914..12013
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<12014..14152)
                     /locus_tag="PK063_05850"
     CDS             complement(<12014..14152)
                     /locus_tag="PK063_05850"
                     /inference="COORDINATES: protein motif:HMM:NF024824.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ96603.1"
                     /translation="MRSDKKPPLKSDKKVLPKVQKKGSLGYNKKSALLEDAITQMNAG
                     KYGRASSALKDLLALDPLNAEARRLFATLHLRLGSLMSARTAFESLAREAMERQDYWL
                     AESLLREYLTAGPRYVPFLEMLGRVYEEKGDVMAAVAEYGKAVEVLLEDPDTEKPNHP
                     SELFARIRSIAPGSPVSFRLAAMFDTVTGQVLQATPQPAVPTQEHEAPQADGVEAPAS
                     AVAPMPWEQIEPLQADVPVAQAPSSPSDVPPTAEVIEPALSAALPVEAVAAVESQKTE
                     IDQSPTLESSEVRTTLTSADSVAPAVPAVGSSDEPMKAAAESEPPAIDPLPALSGEVE
                     SAPPTIPVELPPTNVALVEVGADPIAHAPSSPAPMPWDQVEEVAVVIPPASPSQESTV
                     SDEVAPIALESEVGPAVTVEAVLPSMELPAGTGSQTTASTPLTPAPLSGNQVAEEIIA
                     IPPVTSEVSAVPESAQMPTSETEWSSAPPSDPAPRAIEVLSQSGSHPIVSTPTTPVSM
                     PWDQVEENPILIPPAAGSSAPSVEEVAPATCEETPLPPVIEAGKSDTEPPAQQAEAQT
                     AAPSASSSSEITSSGLSWDEILAAVAAMQSSPASPQSLPSAEPTPATESTVMEEPATA
                     VTAPSDAVEMTAVAPDAPSSEPSLDLGSASSTLSAPMPWEQVEVEDVAIPRQEPEPEF
                     GSATIAVEETGNSSGMALDSTLVVPAVPEPV"
     assembly_gap    14324..14423
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            14548..15372
                     /locus_tag="PK063_05855"
     CDS             14548..15372
                     /locus_tag="PK063_05855"
                     /inference="COORDINATES: protein motif:HMM:TIGR01486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIB family hydrolase"
                     /protein_id="HMZ96604.1"
                     /translation="MQRILIFSDLDGSLLDATTYSYKDASDALAAIEHRGATLILVSS
                     KTRAEMEPLRRSLCNHHPFIVENGGAIYVPNGTFPFPLEGALSREAFQVFQLGAPYAT
                     LRAALKEIGQEIGGRLRGFGDLTLAEVVQLTGMSAGDAQLAMQREYDEPFVMDGDVVA
                     WQDLLAAATRRGLCCTRGGRFYHLMGANDKGMASRQLIEWYRRLEQQKGQTLVTVGLG
                     DSLNDLPMLESVDYPILIQKPNGSYDQDVQLPRLIRADGVGPVGWNRSLIDLLPTL"
     gene            complement(15429..15650)
                     /locus_tag="PK063_05860"
     CDS             complement(15429..15650)
                     /locus_tag="PK063_05860"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96605.1"
                     /translation="MTNKISDIDGEAKARRWLGGEAAVPRYPHRRPSRFVFNRSLLGL
                     VACAISAGFAGGLVVGLLSRRTNTSQRGH"
     gene            complement(15692..16399)
                     /locus_tag="PK063_05865"
     CDS             complement(15692..16399)
                     /locus_tag="PK063_05865"
                     /inference="COORDINATES: protein motif:HMM:NF017373.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96606.1"
                     /translation="MKEFFEKGLLDPLELMARQVLAVLPSLLAMSIIFFAGLVVAWTA
                     SQALERLLRVVGLDRLFDRLGVTGALLRGGVKTDPSRLVGQAAYWLVMIFATVAALGA
                     LNLQPINDFAKSFLAYVPHLVTAGLILVAGWLLSNFVSQAVLIAAVNAGLPPARLVAT
                     CSRWGIQLLAVAMALEQLGIAQNIVVVGFGITLGGIVMAGAIAFGLGAKDLAKDYLER
                     GLSVRTRDGAPDDLRHL"
     gene            complement(16457..17758)
                     /locus_tag="PK063_05870"
     CDS             complement(16457..17758)
                     /locus_tag="PK063_05870"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HMZ96607.1"
                     /translation="MTPGPQLPDATHTTPLTPETEAQVDQFAHTDILVGIPSFNNVET
                     IGHVVKAVSAGLAKYFPEARAVLVNSDGGSTDGTQQVVSQAVVDLKTLFIGDQQSSLH
                     KIITPYHGIPGKGSAFRTIFEIARRLKAKACAVVDSDLRSITPEWIELLVSPVFEQGF
                     DYVAPYYLRHKYDGTITNSIVYPLTRTLYGHRIRQPIGGDFGFSGQLAQHYLDKHVWE
                     SEVAKFGIDIWMTTEAIASGARVCQSFLGAKIHNPKDPAADLSAMLVQVLGAVFALME
                     DHYAVWGKIDGSNAVPLFGFQYEVGVEPVNVNVDRMISTFRQGLTDLGTIWDQILAPG
                     TRQSLRPLGTCSLQDFRIADSLWARVVYDAAVAYRNRVLPLDHVLKAFTPLYLGRTAS
                     FVLDTQGLTSSEAEGRIEALCQAFEKDKSYLVARWNEPHAG"
     gene            complement(18065..18433)
                     /locus_tag="PK063_05875"
     CDS             complement(18065..18433)
                     /locus_tag="PK063_05875"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96608.1"
                     /translation="MMEQQNRPRFIVECTGSRSEDGLLVWNGRMLDLSIPGWSRTGLK
                     GLQAGDLLQLHLHIPGEPKPLSVRLATIRWASESRLGVDPILMDADDQLRLSDFVSAH
                     TTVPSFSTDRKEQIVISDAG"
     gene            complement(18621..18965)
                     /locus_tag="PK063_05880"
     CDS             complement(18621..18965)
                     /locus_tag="PK063_05880"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ96609.1"
                     /translation="MAKSPTTRSHSRVPVSCFLYYLGEGLVGTGKVCDLSVRGWRIEG
                     DKPVTVGMKLTLRVFLPDEPKAIDVEGVTVKWVKDRAFGLETLKLSAAAEARIHKFVE
                     SVLKSADSSRVA"
     gene            complement(19121..19420)
                     /locus_tag="PK063_05885"
     CDS             complement(19121..19420)
                     /locus_tag="PK063_05885"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ96610.1"
                     /translation="MRSFRRFPVQCSVYYSCDAFQGSGIAWNLSLNGWRVDGTHPVDP
                     GTVVTLCIFLPGQHPTVFVDRAIVRWSRGQEFGVEVNTIKADEQARLEQFVTALV"
     gene            complement(19528..19604)
                     /locus_tag="PK063_05890"
     tRNA            complement(19528..19604)
                     /locus_tag="PK063_05890"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19568..19570),aa:His,seq:gtg)
     gene            complement(19730..20446)
                     /gene="pyrF"
                     /locus_tag="PK063_05895"
     CDS             complement(19730..20446)
                     /gene="pyrF"
                     /locus_tag="PK063_05895"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HMZ96611.1"
                     /translation="MMTRIDARDRLIVALDVPSAAEAEALVDRMGDQVRFVKVGLELY
                     TVAGPEIVRRLVDRGKRVFLDLKFLDIEETVRRATARVAAMGATFLTIHANRKALIAA
                     VQGRGQSDLKLLAVTVLTNFDGNDLRDMGIQRSVRDLVTARAMLAAETGCDGVVASGE
                     EPEAIRAKVGPNLLIVTPGVRPAGNATDDHARPTTPTQTIAAGADYLVIGRPIRDAQD
                     PPAATAAILKEMQAAFDHRG"
     gene            20558..20833
                     /gene="rpsT"
                     /locus_tag="PK063_05900"
     CDS             20558..20833
                     /gene="rpsT"
                     /locus_tag="PK063_05900"
                     /inference="COORDINATES: protein motif:HMM:TIGR00029.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000312 - plastid small ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HMZ96612.1"
                     /translation="MPVVHKSTIRRARQSEKRRLRNRATISSVRSILRKVQDAIAAKK
                     PDEAKATLRAATAALSKAVTKGVLKPNTASRRVSRLAVRVNAITASA"
     gene            complement(20817..21929)
                     /gene="holA"
                     /locus_tag="PK063_05905"
     CDS             complement(20817..21929)
                     /gene="holA"
                     /locus_tag="PK063_05905"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: protein motif:HMM:TIGR01128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HMZ96613.1"
                     /translation="MSTSVMSMELPQSLARSGVMPLYAVVGEEDYLRDSSVAALRTAA
                     LGAGAESGFNYDIFHGDDSSIADVLACAAEIPVFAERRVVVYKSVEKLPAREGEKLLS
                     YLASPNETTTFIVVGAKLDGRLKWTQALTKRAVTVNCAPLRDAQLSAWIRQEAAALGV
                     RMQEDAIQLLKEVGGESLYAVKRELEKLAAYVPSDRTVQSSDVEALRGTEPGASVFDL
                     MNAIGAHDHGRAFRILARNVENGEAPLRILGALVWQYRRLWKLKEQLKAGGREGEAAR
                     TFRMDPSRVRGFLAQFPDDQMTQAFEWFLETDSKLKGGSGSTPVRVMEDLLFRLCGKP
                     SKPASAAQRVQPAVPPASRPSGSRPVSNVRTVTRKR"
     gene            complement(21949..22584)
                     /gene="lptE"
                     /locus_tag="PK063_05910"
     CDS             complement(21949..22584)
                     /gene="lptE"
                     /locus_tag="PK063_05910"
                     /inference="COORDINATES: protein motif:HMM:NF016290.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_process: GO:0043165 - Gram-negative-bacterium-type cell
                     outer membrane assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly lipoprotein LptE"
                     /protein_id="HMZ96614.1"
                     /translation="MPRYLLLLVLGLCAVNITACGYQFRVQGAGPTIGGASEPAVKRS
                     QAPKLAILPISNSTYEPNFEIKLANYLRREFSAGAGAEIVGPSAGADLYLSGQIMQIL
                     LPTLSFDQTTTFESRVEMLVSVRIEDAKTKRLVWSQVAKGTSEFFLTQDLQFNRVLQN
                     RALEQAGRFVAEDLASRFLLFLDTGELDKMLKRPVKAEAVPGGNAPPEAAR"
     gene            complement(22589..25024)
                     /gene="leuS"
                     /locus_tag="PK063_05915"
     CDS             complement(22589..25024)
                     /gene="leuS"
                     /locus_tag="PK063_05915"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HMZ96615.1"
                     /translation="MSKSYDHQAVESKWQAYWETHRPFRASDDPSKPKFYCLDMFPYP
                     SGSGLHVGHLEGYTATDIVSRYKRMRGFNVLHPMGWDAFGLPAEQYAVKTGVHPAITT
                     AQNIATFKRQMKRVGLSYDWERELSTTDQDYYRWTQWIFLKLFERGLAYVAEVPVNWC
                     PALSTVLANEEIVDGKSEVGGFDVIRKPMRQWVLKITAYAERLLEDLSLVEWPTSTLE
                     MQKNWIGRSIGAEVDFALADTTGNLRVFTTRPDTLFGATYMVVAPEHPLVDVVTTPSQ
                     RAQVADYRDAAARKSDLQRQELDKVKTGVFTGGYAINPVNHERLPIWIADYVLMSYGT
                     GAIMAVPAHDERDWAFATQYHLPIREVIQGGQVDQAAFVETERGRVINSTTPDGSCSL
                     DGLLPVDAIPKMTTWLETHGKGKKTINYKLRDWLFARQRYWGEPFPIVWVDGEPRPLP
                     EEQLPLPLPETKNFKPSGSGESPLANLEEWLTTTDPVSGQAARRETNTMPQWAGSCWY
                     YLRFIDPKNTRQLVDPAKEQYWMPVDLYIGGSEHAVLHLLYSRFWHKVLFDAGVVSTP
                     EPFKKLVHQGIVLGEDNQKMSKSRGNVVNPDEMIDQFGADAVRLYEMFMGPLESMKPW
                     STRGVEGITRFLDRVWRLMIGEDGALSAAVTNITPTAEQLRLLHYTIKKVTEDIESLR
                     FNTAISQMMVFTNDMTKLDQRPRALLEPFVLLLLPFAPHLSEELWERLGHQPSAGQQA
                     WPPFDPALVVSDRLTIPIQVNGKLRGKLEVDAGASRDQLEPLAKKEVAEWLQGKEPKK
                     VIYVEKKLINFVV"
     gene            25240..>25549
                     /locus_tag="PK063_05920"
     CDS             25240..>25549
                     /locus_tag="PK063_05920"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HMZ96616.1"
                     /translation="MSIYATYIFPRLMDWVLRGERFQTERRLVLAPAHGTVLEIGFGT
                     GLNLPHYPSTITDLHTVEPATLLPDRVARRVANAPFPVHLRQLSAEVLPYASGLFDCA
                     V"
     assembly_gap    25550..25649
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <25650..26024
                     /locus_tag="PK063_05925"
     CDS             <25650..26024
                     /locus_tag="PK063_05925"
                     /inference="COORDINATES: protein motif:HMM:NF024880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HMZ96617.1"
                     /translation="QLSAEVLPYASGLFDCAVSTFTLCTIPDPCAALREVRRVLKPGG
                     CFLFLEHGRSDDPAIARWQDRLNPLQQVVACGCNLNRRIDRLITQAGFRVEQLDRFTL
                     PGVPRIGGEMYRGRAGTAGRST"
     gene            26131..30072
                     /locus_tag="PK063_05930"
     CDS             26131..30072
                     /locus_tag="PK063_05930"
                     /inference="COORDINATES: protein motif:HMM:NF013736.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ96618.1"
                     /translation="MAVSQMFPGNHPSSTSSSDPIDSVRETSLAFQRVALLYQAMPAA
                     LIAGLGCAVALVFVNWNVLPHDRLLAWLAYHLLLSIGRYGLARSFAATSPTPSTIRRW
                     DRAFLTGTLLAGLGWGATALLVFPESSLAHQVFLAFVLGGVSAGASSTLAARFDAFLS
                     FAVPTLAPLILRFFFLNHEQALPMAICTLLFSLLMVYTAYRTSNNVREMLQLKYHNAQ
                     LVDQLSSQLEEGEQTALLLNVHSEHYRFIMEYAQDIIYRTDRSGRFTFINPAVIRLLG
                     YHETEMLGHRALDLVHPNYRRSTEHFYIRQFLRKTPSTYYEFPLLTKTHQTLWVGQNV
                     QLLLRDQEVIGFQAVMRDISARKETEEALRFSQDRYRALFESSPEMLLTVDAEGRLLT
                     VNATAATELGYSADELVGQPISLIVHADDRSTIQQHFADCLRRPGHVLRGEFRKIRKG
                     GSPIWVREASRAVRNPNGQFDILIVCENVTERKGMEDALTHTRQLLESIVEHIPHMVF
                     LKDAKELRFAQFNKAGEQLIGLPREALLGKNDFDLFPREQAEFFTARDRDVLTGGALL
                     DIPAEPIQTKDHGLRWLHTKKLALYDHTGVPRYLLGISEDITDQKQRHEIEQRRLGQL
                     ATQQTVLHKLAEDPSIHSGHPQQAFPVMTEHAAGTFAVERASIWLFDGTQSTLVLQDL
                     FEATSNRHSQGTMLSTKEYPAYLHALETEPYSLAAHAAQSDPRTSELTPSYLIPLGIT
                     SMLDAPIRRHGRVVGVLCLEHTGTPKTWTSEEEAFAASLAAMATLTLEAADRRQAQEA
                     LEQHVRERTGELRRMTAHLQTIIEESPLAMIELDHTGHVTTWNAAATALFGWTREEVL
                     GKELPYVPAGQEQASNELWTSVMNGGAPRNLELCRQRKDGTLIDVNMWGTLLQGPGGQ
                     TTGSIGFFIDVTEHKQLEEQLRQAHKMEGIGRLAGGVAHDFNNLLTVINGCAMLLLEQ
                     VRAEDPLHRSLTEILTAGQRAAALTKQLLAFSRRQVLTFQVFDLNEALSSISSMIERL
                     IGEDIALVRDLTSQPCIIRADRGQIDQVVLNLAVNAKDAMPHGGTLTMATRTVTLTAD
                     TPVPHPAMLPGRYVHLSIRDSGEGMDRTTLSHIFEPFFTTKEEGKGTGLGLATVYGIV
                     KQSQGFIFADSNPGDGATFDMYFPLAQAPSPAAAPATPSRPHCGHETILLVEDQTAVR
                     MLLTQALSDYGYTLIEASSGQEALRLVAAAKTPIHILLTDVVMPQMTGPALAERLRQQ
                     WPSLRVLFMSGYAEGSVLPTFLAEPGTGFIQKPFLPTELAQKLRELLDSAK"
     gene            complement(30117..30803)
                     /locus_tag="PK063_05935"
     CDS             complement(30117..30803)
                     /locus_tag="PK063_05935"
                     /inference="COORDINATES: protein motif:HMM:NF024811.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HMZ96619.1"
                     /translation="MLQHRTDPTPHPVDWSHIDDVLLDMDGTLLDRHFDNFFFEEELP
                     RRYAAKHALAFAEARDRLMSMYRSVEGELAWTDLHYWTEQVQIDVVAMHRELDHMIGF
                     LPDAEAFLLSLRRLEKRVTILTNAHRAGVEVKTAKTGLHRQVDRIVDAFEVGWLKMRS
                     EYWPTCQELVGFDPSRALYIDDDEQCLAAAEQFGIRRIFHRSKSSSQASPVPSARFHS
                     IENFQSILPG"
     gene            30864..32258
                     /gene="der"
                     /locus_tag="PK063_05940"
     CDS             30864..32258
                     /gene="der"
                     /locus_tag="PK063_05940"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HMZ96620.1"
                     /translation="MLPSQAMSRTKPARGPVTPLFTLEGGRLPIIALVGRPNVGKSTL
                     FNRILGTRAAIVDDVPGVTRDRNYADATYRNRHFRLVDTGGLDPTASEGMLSLIRQQS
                     QLAIAEADILVLVLDARAGLTPPDEEVVATLRGSDKPVFYVINKVDTPKADPLVADFY
                     RLGQEHLYPLSAEHGIGVAELLDDLFPHMVDPPGEETPTEIPRIAIVGRPNVGKSTLV
                     NSVLGEARVVVSNVPGTTRDPVDSIATFKDRQYVLTDTAGIRRRGRVERGIEGYSVAR
                     SLRAIGRSDVAVLLLDAEEGVTEQDTKIAGLVLKQGRACILVVNKWDLKADDVDAREA
                     YKQDLERRFPFLAWAPVLFISALEQDFLRGLFALIDQVYFSFCKRVPTGALNQFFQGL
                     LEEHPLPVRKGKPAKASKSAFVTQVATRPPAFALFVGHPDNMTPAYLRFLENQIRKEY
                     HFSGTPIRLMVRKK"
     gene            32510..33556
                     /locus_tag="PK063_05945"
     CDS             32510..33556
                     /locus_tag="PK063_05945"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96621.1"
                     /translation="MVTLVNSDQRFRCISLSLSALLSLSCLPAAGWAEPSAPLIEPPP
                     LEEPAASVEPVAPEALPVEPEPTQTVATAPVSPSVQVSGFIWRSKPGIVFLQTPIGPL
                     SLSSKTTLRDVKNSQKITLWVHGTTTVIDIRERGADKLVHRYVTAMPNFTSPEKQTVA
                     LWTPDGEQSFALGGLAAKIASRSDEQPFTIEVDGSGTVRGLHDVQYDLQVNQVPRTPS
                     SVHLLLNGTVSKLKSNYVFLKTPLGIVTVSGKTGVRNAKVGQEMSVWVQDRHVAIDLY
                     QDGVSTPSRRFLSGPLTYAPEGQSALIMQGPEGAQSIPLAQRPAALSAVKEGLPITVE
                     LGRQGELLDVRRVN"
     gene            33636..34268
                     /locus_tag="PK063_05950"
     CDS             33636..34268
                     /locus_tag="PK063_05950"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HMZ96622.1"
                     /translation="MASRKKSPPASSDGHGLPHSASHPFDQLYRDHVDVMYRFAYRLC
                     GEAEAAKDLVQETFLNAYRAYDRFRGDARVSTWLYAIASHACQRMRRKRKGEPERELS
                     LTEFVPTSEGEFALQIPMEGLSPQEALENKELREILDRAIAKLPRKYRMVLVLRDMEG
                     LSAKEVGDILGLSERAIKSRLHRARLFVRKELSGKGLAEEFHHAVTTVDR"
     gene            complement(34394..34519)
                     /locus_tag="PK063_05955"
     CDS             complement(34394..34519)
                     /locus_tag="PK063_05955"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96623.1"
                     /translation="MLAQPDRLAKGIEEYFAIRAVAEVRADFLADLAGQLVVQIG"
     gene            34604..35068
                     /locus_tag="PK063_05960"
     CDS             34604..35068
                     /locus_tag="PK063_05960"
                     /inference="COORDINATES: protein motif:HMM:NF012264.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HMZ96624.1"
                     /translation="MTRPNPITAVPEPSATDSLSQTRSASRFLHACSSGLPIMVLLIG
                     TGILLAQPSDGLQRGQSLYREHCMDCHGTAGKGDGPKAPFLSPRPGNLVSAATSAKTD
                     KELLRTIAQGKPRTAMPGWKEALPEEDQQAVLQYIRSLIQFSRSPTATPPTP"
     gene            35156..36874
                     /locus_tag="PK063_05965"
     CDS             35156..36874
                     /locus_tag="PK063_05965"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96625.1"
                     /translation="MIRGNLCHHRQTIAILALALAFGSWAGIAESAPAVGGKGHAKTG
                     TPKTTPAIQTAIRYAEALSQGDRVTAGQLDFACQYRHLTASPTKVKQFAPKDDPSYDA
                     CWQNLTDAYAPMLTRSDIAMDIIWPSTGPLLFFGDDLPRAPASAFVADAVGVAPPGSG
                     LHVTALNSRTIPSGSFKLARTGKVLAAPTTLVQLSVQYQDPLTSPVTYAAGNVKWTNT
                     IKRPRRALKSVTLQWVVFSGLKQHGFPGDTAVFNLPVPSQPEAPGMMTDKIPFTTETS
                     RALPESMAWWGPDDQPGVLTAAAARAAIFPDLRDRVALLNRVLIIDPKQPDALTVLTR
                     HLYSALLREARSSHQVPVKDPALGIVLDEFYWNIYAQGMRLDLSNGMEMGGLSQPTPA
                     DFLYRLIPALQTLAEIRPEQLDNRFRLGVAYRWNNDQIPMVETFEALVKDIPEHRRTP
                     KAEALLQLAWSRINKVSWNRILHDTETPRAYANAEASLAFAELPLDKFLAEYAMAYTM
                     IFLPNYGDKEKMLHHLTEAKRWFDEVPGKTNEAWRYFLHTGLLKAVLDADPIFAPILA
                     TVPSQP"
     gene            37145..37450
                     /locus_tag="PK063_05970"
     CDS             37145..37450
                     /locus_tag="PK063_05970"
                     /inference="COORDINATES: protein motif:HMM:NF019911.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEGA domain-containing protein"
                     /protein_id="HMZ96626.1"
                     /translation="MNSDPPGANVLINGTSAGTTPLQYQVPRRGDLTVEVQKPGYTPQ
                     TRVTGRKLSSVGIVDVIGGALFLLPLLGLIAPGAWEQDPGIIGITLEPDHPQPAQPQ"
     gene            37500..38546
                     /locus_tag="PK063_05975"
     CDS             37500..38546
                     /locus_tag="PK063_05975"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="HMZ96627.1"
                     /translation="MIDVKGYAARTAKSRLAPFTFSRRNVGRQDVLIGIRYCGICHSD
                     VHQARDEWGGSIFPMVPGHEIVGVVEQVGASVKQFKVGQMVGVGCFVDSCRTCPQCKK
                     GEEQYCEGHISFTYNGKERDGVTPTYGGYSTKVVVDQRYVLRIPKQLRPEEAAPLLCA
                     GITTYSPLHHWGVGKGHRLAIVGLGGLGHMAVKIGKALGAHVTVLSHSDKKRRDAKRL
                     GAKDFYKTSDPKTFTTLAKQFDFILDTVSAPHDLDAQLELLKTDGTMILVGVPDKPAQ
                     LGAFPLILKRRRLVGSLIGGIQETQEMLDFCAKHKCGADVEVIPIQKVNEAYDRLVRG
                     DVRYRFVIDMGSLT"
     gene            complement(38730..39695)
                     /locus_tag="PK063_05980"
     CDS             complement(38730..39695)
                     /locus_tag="PK063_05980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multicopper oxidase domain-containing protein"
                     /protein_id="HMZ96628.1"
                     /translation="MTVRNIRFRQSVIRTVLGLAAMSGLAMQPVESAFAKVVEVSMTA
                     VETKLVIDGEGHTYDAWTFNGQFPGPVIRVQEGDEVVFSLTNPETNGRPHSMDFHAAE
                     TNFLEHYKEVRPGESLQYRFKAKWPGVFAYHCGASPMIQHIARGMMGAIIVDPKDPKA
                     MPKADREYVLVQSELFKDPDDVDGMFDRKYQHVVFNGAVFRYDPVHSKAGGAFLEAKP
                     GERVRFYFVNAGPNNVSAVHPIAEIWDDVWESGNPANHTRGVQTQLIPPAGAAILDMV
                     LDGNDGVYPIVTHSLTDALRGAIALLKVDKDAKQLPLMPLVEPAK"
     gene            complement(39855..41219)
                     /locus_tag="PK063_05985"
     CDS             complement(39855..41219)
                     /locus_tag="PK063_05985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HMZ96629.1"
                     /translation="MSDVQRQIETYIKDIRPQYEDMLGQAVEIPSISMDPRHAPDVRR
                     MAELATQYLRAAGAEAQIVETPGYPVVSGGWTVDPHYPTVTVYNHMDVQPAQEPEWKQ
                     APFAFQNDHGIYRGRGATDDKGPALAALFGARYAIDQGVPINVRFLWELEEENGSPSF
                     ASAIKNRAAIPAPDSVVISDTIWLSKNQPAMPYGLRGLLGARLTLRTGTKDAHSGVTG
                     GAARNPLVELMEIAHACVDAKTGKVKIPGFYDEVVPPTKAEIASFLKSGFQVSKFKQA
                     YGFKTLRTHDPAEVMRRIWAAPTFEVHGLTGGYHGPGVKTIVPGHGELKISMRLVPGQ
                     TPEKIFALLKHYVAKLNPAVKVEREGMLHPFRGVFDGPYVEAVKRAVLAGFGKEPAFI
                     REGGSIGAVVTMQKAWKVPILFMGLSLPEHGYHAPNEYFDWGQASGGIKAFAHYFSDL
                     AAKR"
     gene            41419..41862
                     /locus_tag="PK063_05990"
     CDS             41419..41862
                     /locus_tag="PK063_05990"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96630.1"
                     /translation="MGTALLACLALCLSGGNRVFAQEAVTVQEVLADPALFHLRQITI
                     KGTVRQVQPLDPYEIPAGSTCYGGYLFSLEDDTATLSIAVPGLCGVPMVKDPDVEDGA
                     RVVVEATVQAPSHGGYALSFKGAKIAMDQEGVVQAIANRITPLVE"
     gene            41866..42816
                     /locus_tag="PK063_05995"
     CDS             41866..42816
                     /locus_tag="PK063_05995"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HMZ96631.1"
                     /translation="MTTRPLEQTARVAAPAHTRVGWIGTGVMGASMCRHLQAAHYRLT
                     LFTRNRGKASAILAKGATWADSPRAVAEQTDILITMVGFPRDVRQVYFGDHGVLAGAG
                     AGMVLVDMTTTEPSLAQEIAQAAQSRGVFAVDAPVSGGDIGARDATLSIMVGGEASAV
                     QTIMPLLECLGKKIVHQGHSGAGQHTKLCNQIVIAGTMIGVCESLLYGYKAGLELPRM
                     LESIRGGAAACWTLDNLTPRILARNFDPGFFVEHFIKDMGIALEEARRRQLTLPGLTL
                     AHQLYEKVEALGHGRSGTHALMLALEALSNIDPTRPSTSL"
     gene            42830..43561
                     /locus_tag="PK063_06000"
     CDS             42830..43561
                     /locus_tag="PK063_06000"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96632.1"
                     /translation="MRTGTHPLVLALILTITCTACTGTRGLNRHILQESFHDHPDVTT
                     DRAIAATMATQATLPTPYRLAIYFKHEDFPSRPALQRVDWVSSDGARVQRSLEPVQEE
                     GILQRTFLLANSTVQGNTLRDIRLAAARYNADAILIIDGASAFERYNNGHAWWYATGI
                     GAYFAHGTECHALFMMEGTLWDVRTGYLYGTQTAEGETTLIGPAPSLDDKAAVAEAKD
                     VAMARFGRELADTLRLLKEKQKAIP"
     gene            complement(43815..45047)
                     /locus_tag="PK063_06005"
     CDS             complement(43815..45047)
                     /locus_tag="PK063_06005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HMZ96633.1"
                     /translation="MEPILPLRNDIGLAVRPIFSAGMSRLGWVLFFWLLIAPAYAAEP
                     SSTPGDSPAVSADSGLWHYGAYLDVAYILNFNFPENHLWRNRATAARHNEFAPNMALA
                     YVRKDVNESSRWGMELGVQGGYDSERFAFLQGEREVSGADTLRHIHRANVSYLAPIGK
                     GLTITAGLFNSLIGYESLYAKDNANYTRSWIADNTPYMMFGVNAKYPVSDELTITAFV
                     INGYYHLSHPNDQPSYGGQWAYKATPRLTLTQTLYGGPDQSNTALQFWRFYANHIVEW
                     KGDDLTLALSYDIGTENIADRPGHPRAFVTGGNMVARWHVAGPWTLVARPEFYWDRNG
                     RWTGSEQFVKAVTSTVEYKIPYKWTNTILRLEHRWDESTGAGGGFFRRGEVQPGVLSL
                     TPNQHLVLLGILWTFDSP"
     gene            complement(45170..45877)
                     /locus_tag="PK063_06010"
     CDS             complement(45170..45877)
                     /locus_tag="PK063_06010"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ96634.1"
                     /translation="MPSTTTHEVTVLLIEDEAEIRRFLRTTLPPYGYRLYEATTGADG
                     LAQISARNPDIILLDLGLPDMNGTAVIEKIRAWSNMPIIVLSARDQEQVKVQAFDLGA
                     DDYVTKPFGVDELLARMRAALRHAHRPIGDAVEPVCTFGEVTVDLGRRQVFVSGTEVH
                     LTPIEYKLLTTLVRYAGKVVTHRQLLKEVWGPLHVDEGHYVRVYMRQLRNKIEADPAQ
                     PRHLVTELGVGYRLRAE"
     gene            complement(45890..48598)
                     /locus_tag="PK063_06015"
     CDS             complement(45890..48598)
                     /locus_tag="PK063_06015"
                     /inference="COORDINATES: protein motif:HMM:NF014728.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HMZ96635.1"
                     /translation="MENQRPDPDLLLRRVQAEEADQTRGRLKVFFGATAGVGKTYAML
                     QAAHEQQRDGIDVVIGWVETHGRAETEALVHGMPTLPPREVVYGGSRLRDFDLDAALA
                     RRPQLLLMDELAHTNAPGSRHPKRWQDVRELLQAGVHVYTTVNVQHIESLNDAVAQIT
                     GIRVSETVPDAVLEQADDVELVDLPPDDLLQRLKDGKVYLPDQAQHAIKHFFRKGNLI
                     ALREMALRRTAERVDQQMEVYRRDHAVVGTWPAAETILVCVNLKPRGPMLVRAARKMA
                     TGLHARWIAVYVQTSKHLRLSDQERNQGVDTLRLAERMGAETVTLTGEDVSAQLLAYA
                     RSRNATKIIVGKPLRSRWKEWLFGSVVDDLVRGSGDIDIYVMTGEGGTGKPLVKGLLQ
                     RTSERRNYGYASAVVGACTALSLVMSPYFGQANLIMVYLFGVVVVATRWGRGPSALAS
                     LMSVAAFDFFFIPPYYSFAVSDAQYLLTFAVMLLVALLISRLAAHKSQQAEAALIREK
                     RTAALYAMSRELITQRGVDKLASVASRHIHDVFHCQVAVFLPDREGRVHLHRGEALHF
                     ELDPKEAGISQWVFDHKESAGHGTNTLSGSDSLYLPLLGSHGAVGVLAVRSSRPAELL
                     APEQLHLLETFANQMALALERARLAEEAQEAHVQTETERMRNAVLSSVSHDLRTPLAT
                     IVGASSALLSTTRPLSTESQQDLVRSISDEAGRLDRLLKNLLDMTRLEAGAMHLRKEW
                     HALEELVGTALARVKSRIATHTVTTAFPVNLPLVLVDGVLIEQVLINLLENAAKYSPT
                     ASPIEVTASVKDGVILIEIADRGPGIPQGEERRIFEKFYQLHPEREGGVGLGLTICRG
                     IIESHGGRIWVDSRSGGGSSFRFTLPAEKSQPTVEPEANQHDSAAI"
     gene            complement(48684..49265)
                     /gene="kdpC"
                     /locus_tag="PK063_06020"
     CDS             complement(48684..49265)
                     /gene="kdpC"
                     /locus_tag="PK063_06020"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014960305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008556 - P-type potassium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpC"
                     /protein_id="HMZ96636.1"
                     /translation="MAAQLRSALMVFFILTILTGVAYPLAVTGIAQLLFPHQANGSLI
                     YKDGKPIGSTLIGQPFDDPKYFWGRPSATAPFPYNASASSGSNLGPTNPALTEAVKTR
                     VAALKAADPRNDAPVPVDLVTASGSGLDPHISPAAAEYQMRRVARARGKDEAVVRTLV
                     IQHTEGRQLGLLGERRVNVLALNLALDASGQAR"
     gene            complement(49276..51387)
                     /gene="kdpB"
                     /locus_tag="PK063_06025"
     CDS             complement(49276..51387)
                     /gene="kdpB"
                     /locus_tag="PK063_06025"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014449359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA];
                     GO_function: GO:0008556 - P-type potassium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HMZ96637.1"
                     /translation="MTTSTKARPLFDPPLVRQALLDALRKLHPRIQVRNPVMFVVFVG
                     SLLTSLLFFQALFGAGEAPTWFILAISLWLWFTVLFANFSEAIAEGRGKAQADSLRKS
                     RTELTAKRFGTPASGGDYLAAPAAIGKPGEVYSLVPASLLKKGDIVLVEAGDYIPSDG
                     DVIEGIASVNESAITGESAPVIRESGDRSAVTGGTRVLSDWLVVRITTSAGETFLDRM
                     IAMVEGARRQKTPNEIALNILLAALTVVFLLATVTLLPFSLYSVHATGQGAPITVTVL
                     VALLVCLIPTTIGALLSAIGIAGMDRMVQANVIAMSGKAVEAAGDVDVLLLDKTGTIT
                     LGNRQATAFIPAEGVPETSVADAAQLASLADETPEGRSIVILAKERYGIRGRDIHAMG
                     ATFLPFTAQTKMSGVDLDDRQIRKGAAEAIEDYVTQQGGSFPPAVRDAVETIAMQGGT
                     PLVVAEGKTVLGVIHLKDVVKGGIKERFAELRRMGIKTMMITGDNQKTAAAIAAEAGV
                     DDFLAQATPEAKLKLIRDLQAGGRLVAMTGDGTNDAPALAQADVAVAMNTGTQAAKEA
                     GNLVDLDSNPTKLIEIVEIGKQLLMTRGALTTFSIANDVAKYFAIIPAAFATTYPALG
                     ALNVMGLATPESAVLSAVIFNALIIIALIPLALRGVKFRPIEASLLLRHNVLVYGLGG
                     IIVPFIGIKLIDLLLVALGLV"
     gene            complement(51411..53216)
                     /gene="kdpA"
                     /locus_tag="PK063_06030"
     CDS             complement(51411..53216)
                     /gene="kdpA"
                     /locus_tag="PK063_06030"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:NF015753.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA];
                     GO_function: GO:0008556 - P-type potassium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HMZ96638.1"
                     /translation="MTINGLAQIGLFFLVLAALVKPLGWYMARVYTGQACGMDRVMGP
                     FERLIYRVCGVREAEAMNWTSYAVAMLLFNVAGLVALYALQRLQGLLPLNPSAFGAVA
                     PDLAFNTAVSFITNTNWQAYAGESTLSYLTQMLGLTVQNFVSAGTGMAVLVALIRGLT
                     ARTASTIGNFWVDLTRSTLYILLPLSAVLALVLVSQGTVQTFGLYHQTALLQPVTYDK
                     PVVDAAGQPVVDEKGVAKMESTTGIEQVLAVGPAASQVAIKHLGTNGGGFFNANAAHP
                     YESPTPLTDFILILAETLIAASLTYTFGMMVGDTRQGWTILAAMLSVLAFFVLGAYWA
                     ESAGNPRLTALGVEQNVQIAQSGGNMEGKETRFGVARSALFATVTTATSTGAVNSMHD
                     SFTPLGGLIPLLMMQFGEVILGGVGSGLYGMLVFAIIAVFIAGLMVGRTPEYLGKKIE
                     AYEMKMAALLILIMPIVVLGFTAVAVVTESGTLSILNAGAHGFSEILYAYTSQGNNNG
                     SAFGGLNANTPFYNVTGALAMLVSRFWLAIPTLALAGSLARKKMVPPGLGTLPTHTPL
                     FVVLLIGVVIMVGALTFVPALALGPVVEHLLMVAR"
     gene            complement(53216..53305)
                     /gene="kdpF"
                     /locus_tag="PK063_06035"
     CDS             complement(53216..53305)
                     /gene="kdpF"
                     /locus_tag="PK063_06035"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017877382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031004 - potassium ion-transporting
                     ATPase complex [Evidence IEA];
                     GO_function: GO:0008556 - P-type potassium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HMZ96639.1"
                     /translation="MNAMYVLGAVLSLGLLVYLMVALLKAEWF"
     gene            complement(53319..53588)
                     /locus_tag="PK063_06040"
     CDS             complement(53319..53588)
                     /locus_tag="PK063_06040"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96640.1"
                     /translation="MGKIFSEIHFLRFFTPFLLSARYLEHVVEEKGRAAMWLVGDGLE
                     RDSGEARLNTCAVSLRNIDMDLIYLAIAAVFFLLSGWLISALDRL"
     gene            complement(53758..54279)
                     /gene="nuoB"
                     /locus_tag="PK063_06045"
     CDS             complement(53758..54279)
                     /gene="nuoB"
                     /locus_tag="PK063_06045"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_function: GO:0048038 - quinone binding [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoB"
                     /protein_id="HMZ96641.1"
                     /translation="MFRIIKKSLTTGVVTGQYPMAKASQEPVSREAIEKVKPFRRSLT
                     IREVDTGSCNACEMEMNALANPVYDVERFGVEIAASPRHADALVVTGPVTVNMERALK
                     DVYKQTPDPKLVIALGDCAITCGMFKGSYAVTGPVDRHIPVDVRIAGCPPRPVEILAV
                     LAELRKDCPDSDQ"
     gene            complement(54336..55928)
                     /locus_tag="PK063_06050"
     CDS             complement(54336..55928)
                     /locus_tag="PK063_06050"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: protein motif:HMM:NF012566.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit C"
                     /protein_id="HMZ96642.1"
                     /translation="MPDGLTAAARVQEAFPQGIIQVGSMQGVPMLRLRKPDVPAVARY
                     IHTDPELRGSLSLLWAIDHRPREARDELWYLFTLAARKDWLLLTVDLAEEEREFASIT
                     PMVHAAKWYEREIRDLFGLIPVGHPDMRRLVRHEHWPKGMHPLKKEFAWDQVLERAQG
                     EYAFRKIHGDGVFEIPVGPIHAGIIEPGHFRFSVAGEPILQLEVRHFWKHRGVEKLFE
                     QQRLTEAVPLAERVSGDTSVGHSLAYCQAVETLLGMTVPPRARYLRSLFLELERLHNH
                     IGDVGAICNDTAYALAHAHCGRLKEQLMQLNDGLTGSRFLRGVNRVGGVSIDLSGVQL
                     SQVDAELQAIEQEFSGIEKILLANASLTERLENTGVLSESIAWDHAVMGVVGRASGID
                     RDLRRDRPFAAYPECQPKVAVYRYGDVRARMRVRLDEVHDSMRLIHTLRRQLPMGPLA
                     TQAVEPVTQGQWAISAVEGWRGEILYVVMAGEEGRIHRCKVRDPSFVHWPAIQWAALG
                     NIVPDFPLINKSFNLSYAGNDL"
     gene            complement(55934..57466)
                     /locus_tag="PK063_06055"
     CDS             complement(55934..57466)
                     /locus_tag="PK063_06055"
                     /inference="COORDINATES: protein motif:HMM:NF012581.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proton-conducting transporter membrane subunit"
                     /protein_id="HMZ96643.1"
                     /translation="MWPVIVLLAGPVLAGLLSLVIQRARLLHAVNFTTMLGLAVAETF
                     LTKRVLAEGSVTTLGSLVYIDALSDFILIIITAIGLSCSLYMWSYMDEQVARAVIAPK
                     HLGVFFFLFHMFLFAMVAATMANSLGVQWVAVEGTTLATTFLIAFFRRRESLEAGWKY
                     LILCSVGIALALFGVVLTYYSSVRVLGDASSALNVTALIGVADRLDPNVLKLAFLFIL
                     VGYGTKVGLVPMHTWLPDAYTEAPAPVAAMLAGVLETVAVYTVLRSKALVDQALPPQF
                     TGNLLLTFGFVSFVVASLFILLQHNYKRLFAYSSIEHMGLAMLGFGVGGLVGTFGGLF
                     HLLNHALAKALAFFVAGNIHRRYDSLEIDHVRGLGRSQPITALATLVAGFALVGLPPF
                     SPFVSELLVVSALSAQNFASDTMHVGRFVAVTVSDEMRSLGLVGVFLFFGVVLFGGMM
                     ARIGAMVWGTPQDEIRRGEPWTVGHVPMLAMIVALLGLSVMLPESLRTLVTRAVHVIV
                     VR"
     gene            complement(57503..>58217)
                     /locus_tag="PK063_06060"
     CDS             complement(57503..>58217)
                     /locus_tag="PK063_06060"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96644.1"
                     /translation="WRCWPWCSSTRCEGKAMSESTQLGSQLVDLCSVLLLLSCFAIVA
                     QRRLSACVDLFALQSFFLATTAALVAFLTGHRHIYLAAALTVVIKVIVLPRILRKVIE
                     RLNVSRELVMNINIPAGLLICGGLVVVAFFITQPIIPLGYLLTRDSLALALAIILIGL
                     FTMIARKKAVTQMVGFLVMENGVFLGTTAAAYGMPLIVELGVFFDVLVAGLIAGIYTH
                     RLQDAFDSVDTSELTVLKE"
BASE COUNT        12449 a        18138 c        15953 g        11377 t
ORIGIN      
        1 cgatggttat agtccaggcg aagtgcccaa ttctgcgcca gggtatatcg ttggcccact
       61 gaccaccgaa catcatcgga tcgatcgccc aacgcatatc gaagataggt tgctgtcgcc
      121 aacacccgcc agcgttcggc caaatcggca taaaaacccg ccgatgcacc gccgcccaca
      181 cggtgccgct cctcgtaggc tctactgtaa ttcccctcca cttccgcaaa cgcaaaaaac
      241 acttcccggc gtaacatatg cgtctcggcg gaggccccga tcccgccatt catactccag
      301 ttgctgcaca actggcattc gccatgccgg atggtctgca tcccgacatt caatttccag
      361 gatggggcac gaaacaggct gtcgatgggc gagagggata ccacgttcag cagggttgcc
      421 cgctcaatcc gggcctggtc ggcccggtta tagtgacgga ggctgattga gccgatctcg
      481 atttgagcat ccggcgtata tcccggctcg ggatcgagca aatcgtgata cgcggtccgc
      541 acgctaacct cttcaaagct atcgttatta cgccagcctc ccccgagact cgcgcgggag
      601 gtcttgtgcc ctaattcggg ttgcgtggca aacggcagaa tcgagagctc ctcggaggga
      661 attcgcaaga ggctgcgcgc ggtcagaagt tgacggttgt gatcgcgggc tgctgtcgct
      721 tgcgactcat ctcgttcacc cgtatagcgc acatagtcgg atgccacatc cagaacgaac
      781 gcctggcgcg ataacggcaa gctccggacg tcatcggact gcgccactgc cgcatcacgc
      841 actaatcgct ggaccaatcc atgctcagcg acggtgagct gttcgcgctt gcggcgaatg
      901 agcgtcacac gcgaggggcg aaacgcggtg tccgttacca gtcccggttg atcggcgagc
      961 aggcgaacgg tgtctgcagg aatggtccag aagcgaaact tgtcggtcaa gcgtaacgaa
     1021 gggtcggcat attccagtaa cgacaagagg tggtaggaac agttttcctt aaagaaaaaa
     1081 taatcgaatg acgcattccc gagctcccag gcatgcatga gtaatcgccg gatttggggc
     1141 gcgtcgaagt tgagacggta ttcccagata tcgcgatttt ccatgtcccg gtactcttgc
     1201 actttcaggt agtagggtat cgtagaaaag tatccgcgat agcctccgaa aatgccgcgt
     1261 accggatacg ccaatccttc gtctttgggg acatccgccg caaaattgat ggtataggcc
     1321 aagatacgcg tatgcggcgt ctgaccttcc tggtcgatgc gcaacagcgt atggccaaac
     1381 atggaggccg ggttattcat aaaggccgag ggaaatacca gcgtgacgga tcgggcatgg
     1441 aactcctcga accatcgctc gaaccgatcg cagcgcatga ccggaagttg tcccgggtca
     1501 aaggcaagac gctcgtggag ccacgcatac cgcgcgacaa aggcacattg cgccggctgt
     1561 ttggagcggc caaccaggtc cggcgagaaa aattgtgtca gcgttgaatc aagttcagcc
     1621 tcgggatctg tcttgccgtc aggagacaga aagaaacccg gctcgtcctg ttcactggta
     1681 aacccaccga agagattggc tcgataatgg agcaagagat gccattcgcg ctcatctgcc
     1741 agcttggcct gatgagcgcg ttgaaggagc tgggacaagt acggcgccgg cggctcttgc
     1801 gcctcggtgg aagtcgcgag gaaaaggccg actaggagga tcaacaaaat atgcacgatt
     1861 ggagacagaa tgcagcgcag ggccccggcc aatgaccgaa gccctgcgat gaatcaatta
     1921 gcggctgacg gcttgggcga gaaccgggct cttggagacc gcatcattca gcgtcttcac
     1981 caaggccacg gacgaggttt caccatcctg caccagtgcc gtgtagcgct cctgggttaa
     2041 ggcgaagaag gccgcatgct gttcggcagg cacgcccatc agcgtcgcga gggacgccaa
     2101 gtgctcgcct tttccttgcg ccatttcctg cgtcaggttt tcgaagttca acaaggcaaa
     2161 catggtggtc ttctgatccg ccatgacctg accatcattc gtacaaccgg acgttccgga
     2221 gctgatcccg aatgtcccgc tcccaaacgt gccgttcgtc gtggccatca tcacctgcgg
     2281 ggcgatgttc ttctggtttt tataatcggc ccaggccaac ttccccagac cacagccggg
     2341 tcccgtatca ggattggctg ccagagccaa tccggcctgt gatgctaccg ccaccacccc
     2401 caacgcaacg atgatttgtc tcagcataag tcctcctcct cgtaacaagt gaatgactcc
     2461 gcccgaccga ctgtccataa atttctcttt cattatagac aacccccacc accatgtaga
     2521 gcaaaaaatc cgcgcatcgg cggttctcgt cattccgctc gatcggccaa catgatgtgc
     2581 cgcgtttcaa ttgatccatt ttgaaacagc aggactccca gcgcgcgcgg gagacgaaag
     2641 cgtttcggtc cggcggatcc cggattgaac aacaagaccc cgtctcgcca ttccgccttc
     2701 ggctgatggg tatgcccata cacacacacc gttggacgga tgcgctccag cagatctatc
     2761 ccgtcccctg tgagtcgccc accctcatat agtcggtggt acaccgcgat acgatggccc
     2821 gccagttcaa tggtctgctc cacaggaatg ccgctggcat cgaatccatc cacattcccg
     2881 gacacggcgg tcaccggcgc gatccgctcc agttgcgcca ggacatcacg gggaccgata
     2941 tccccagcgt gcagaatatg ctccacccct gcaaaatggc gagtgatcga aggatcaaac
     3001 agcccatgcg tatctgagat gactccgatg cgcattccgc tccttgcgtt acttcttagg
     3061 ctcagacact gccaatgaat cctgaatggt tttccattga aaggtgaacg gctcaggggt
     3121 tcgcttgggc aatgcggcca actccgcctt caagagcgcc gcccgcgccg cgctcatggg
     3181 atgcgtggaa aagacttcga cgcgttcctt gtccttttca gacagccgtt caaaaaatcg
     3241 gatcatcccg tccggtgcaa tgcgcgcgtc agataagagc cgaatgccgg tgacgtccgc
     3301 ttccgtttcc tgggcgcgcc cgaacttcaa cgtcactaac tccatgccca cctgcttggc
     3361 caggccggtc aagccctgtt ggtcacccag cagaatcccc acaacggcag acagtcccag
     3421 catcttgacc atgcgttcca tgccgtgacg ctgcaagaca tggttcaatt catgactcaa
     3481 cacgccggcc acttcttcgc cgctttctgc tttggtcatc aacccggtga agaccacgac
     3541 atagccgccc gggagcgcaa aggcattcac cacggggctc tgcacgacgg agatctgaaa
     3601 tttgtaagga ttattgggaa ttttttccgt caaccgctgc gtcatttcct gcactgcact
     3661 gaccgcgggc ccttccttca gcacggtctc cttggacaga aaatcctgat acacggtttc
     3721 gcccaatttt tgttcccact cgatggggat tctggccacc gcccattcga ccatcaggtc
     3781 cgtcccgaac cacaacagca gccccaggcc gaatacgacc cccaacacac tgccccacaa
     3841 gaggcgatgg ctgtgtcgcg cccgacgaac ctgctctgcc gcacgctcca gatgggccgt
     3901 caactgaggc ggagccgcac ggcggaaggc gacgatcaag gcgggatctt ttacatagag
     3961 tgtccaaacg gatgggccgg tgccccagga caccaccagc tgatcgtgat ccaatccgcc
     4021 ggcttcaacc gccatgtcag caaaggtcac gacctgttcg gcgagcgcag actcacccat
     4081 aggactgaca cgcaaaccct cttcaaccag catgacggta cagggcacac cggctcccgg
     4141 cagtccctca ccgaaacaga gtgcgttggg agtcgcgttc atagggcttg gactttcctc
     4201 atgaagaact atcgcctgtg aagggggcgt tcaaaacggc ggccaacgcg gccgcaggcg
     4261 agaaaaaacc ggaggcgtac cctatggggt acgttgagga ttttttcgaa ccgagaacaa
     4321 agttggcagg cgttttcagc gcccgccatt cagccgctac tccgaaacgg gaatgaattg
     4381 tctgatccag ttcccgaaac tgccgggatt acggctctgg atatagacga cacccggccc
     4441 gcggaaacgg cacaccaaac cttcgcccga ggtcaagctg gcaatccagc ctgacgaggc
     4501 cttttcgatg ttgtaggtcg tcgttgagct ccaggcgacc aggtggctgt tatcgacaat
     4561 gtattcttcg ttcggtttca attcgatttt atgaatggcc ccgaagctgt tgagaaccaa
     4621 ctgcccggtc ccgccgatct tcagaataaa aaacccctcc ccgcccagca atccacgcgt
     4681 cagactttgc atcttgcttt caatcttcac gccttcggcg cccgcgagaa acccgtcctt
     4741 ctgcaccatg tactcattga cgccgtccaa ctccagcagc acgatttcgc cgggcaccgt
     4801 cggcgccagc aagacttccc ccgcaccccg gctggcccgc aacgtctgga agaaaaattt
     4861 ctcaccactc aacatcttcc gcgaaagggc cccgagaaac ccgccttcca tcttgctctc
     4921 gatatcgatg gtcggcgaag cggccaccat ggcgcccgac tccgccttca ccgtctcact
     4981 ggcgtccaga tacacccgca ccattggaaa ggcccccgga taaagaattt cacacttcat
     5041 cgcccgctcc cttcatgaac tgtcagcctc atcatgcgat cgattctgtg gaatgtcccc
     5101 ggtcctgtca agcagactgt tgagacggac cgtccctccg gccacacggc acctgttttc
     5161 cgctcaagat cgatcacgtt tcagccgata cagcccaaag agctatcctc aggtgctgac
     5221 gggcaaccgc tcttgtcggc cttcccgctt atggactcga agagacacga gagccaggca
     5281 tgaaacgcgt cgtgatcgaa gagctcacac cgggaatgat tctcgccaag cccgtgacca
     5341 acaatacggg cctagtcgtc cttcctcccg gcgccgaact ggatgaagca accctctctc
     5401 gactccagcg cctgggcctc acgtccgtct atgtcgaggg cgacgccggc gatgccagcg
     5461 gaaagaccct tgccgagttg gaagccgagc tcgaccaccg cttccgcctt gtgagcgatg
     5521 acccgattca atgccagatt cgtgaagcga tccgccagca actccggacg acacatgggg
     5581 tagccgacca ccaggaggca cctccagcca catgaagcct tcggccaacg tagatctccg
     5641 gcgacgcatc gagcaggtcg gcgaattgcc gaccctgccc catgtcgtcc agaaactggc
     5701 gtcgatgatc ggccgcccca atgtctcagc cgaggaaatc ggcgccctca tcgaaaaaga
     5761 ccaggtgctg tccgccaagg tattgcggtt ggccaattcg ccgttctacg gatttccctc
     5821 acgcatcgcc tcagtcgccc atgcagtcgt cgtcctgggg ttgagtgtcg tcaagggcct
     5881 cacgctgtgc gccaccgcgt tcgacatgat gaaaaacgcc gggatgaatg acctttggcg
     5941 ccattcgctc ggggtggcca ttacggcaca tattctaggc gcaaaagccg gcatgaagaa
     6001 tcccgaagag gtgtttgtcg gcggactgct ccacgatatc ggtaaggtgg tgctctacgt
     6061 caaatggccg gatgtcggcc agcagatcac ggccgccagg aaagacggct cacgatcgct
     6121 catggaaacg gaacaggaac tatttgccgt gacccatgcc gacgtcggag ggtggctcgc
     6181 caccgcctgg catctgccga ccactctgcg cgagccgatt cttcatcacc atatgccgac
     6241 ggcagcccaa gacgcgaagc tgcagaccgc catcgtgcat gtggcggatg tgctggtgaa
     6301 gggcctcgcc tgcggcaacc ccggcgacga cctgatccct ccactttccc gtcaggcctg
     6361 ggatctcgtc ggcctcgatg cgcaaagtct cgcgcagagc ctcgcccaag ccgcggaaga
     6421 atttcaaacc atcgacgact atctatgagc gggtcgcctt ccaaccgacg tatcctgctg
     6481 ctgcaccatg atcccgtcga aatcgagcgg ctgacggctg gcctcagccg tgcaggattc
     6541 agcgtcgtcg tggccgatgc cggacggcta gcgctgcatg aattggtgca tgatcccccc
     6601 tgcctggtgt tggcggcgga agggacgaat ggacggtccg cggataccct cgcgaaggag
     6661 ttgcgcgcgg atccctttct cggccggctg ccggtgatca ttctgattcg ggatagccgg
     6721 gtgaatgatg tggattgggc ggcgctcggc gtcgacgact atattgccgt accctatcgg
     6781 cccgaggaag taccacaacg ggtgcgcctc tgcctcagcc gcctggaacg gtcgctggat
     6841 gccaacccgc ttacgcggtt gcccggcaac agcacgatcc tccacgaaac cacggcgcgg
     6901 attgaaagcg gcgctccgtt cgccctcgcc tacctggatc tcgacaactt caaatcgttc
     6961 aacgaccggt atgggtatgc gcgaggcgat gaagtcctcg tggtgacctg ccgcatcctc
     7021 accaccgtcg tcagtgaact ggcgggcacg gacggattcg tcggtcatgt gggtggggat
     7081 gattttgtct ttatgagcgc gccggccacg atcgaagcca tttgtcagac attgatcaaa
     7141 cggttcgatt tggtgattcc ggacttctac gatcccgatg atcgcggcaa ggggtttatc
     7201 gactccgtcg accggcgcgg caaccacgaa cggttttctc tcatgagcct gtccatcgcc
     7261 gtggttacca acgaacatcg agccattacc catccgggcg atgtcagcaa gattgcctcc
     7321 gagctcaaaa aaatcgccaa gagccagccc ggcagcgtct atgtgaagga tcatcgaaaa
     7381 gccgagacga ctgacgcccg taccacctga cgcatcacgg cctacgaact cgccggaaga
     7441 ttactgaccg gggactccag caggcgcctg cccgccgcca ctgccgccat actggcggcg
     7501 aagttcccgc cgataggcac gacgttcctc cggggacatt gtctgaaact tttcccgcaa
     7561 ctccttccgt tgctccggag gaagagaccg gaaccatcgc ctggcgtccc gcaccgattc
     7621 gcgccgttca ggcggcaatt ggcggaactg ttgataccgc tcacgcaatt gctgccgttg
     7681 ctccggggga agcgatcgcc attccttgaa tcgctgcttg gcttcctgac gctcttcggg
     7741 cgtcatcgtg ccccactgcc gcgccccatt ccgcaaccgt tgctgtttgc gcggggggag
     7801 ctgatcccag ttgtcgctga accgctgcaa caattgctgc tcgcctggac tgagctggct
     7861 ccatgggacc ccggtctggt caccttgcgc ccaggcaggc gacaatgcga tgaacactgc
     7921 catgattcct accagcaaca cattcatggg ccggtttgca tccttatggg gctgcgaggg
     7981 cgatccttcg cagacggtgc cggcttctct ggcgcaggct tctgagcgtc tgaagacatt
     8041 ccgctgcgat tcggttgtgg ttccacggaa gactgcggca cttgatcgct ggtgatggta
     8101 aagggatcga cccactgtcc atcctcatcc tgccagctac ccaggaaatc aaggaactcg
     8161 gggtccggct cctctgccgg ccgtgccggt accgatgccg cctctgctat tccggtggcc
     8221 aagaagaaca ggagcatcag tcctgcacta ccccgtcgtg gcagtaccat cggccagcca
     8281 atcgtaaaat tcgaggtcct cggacaattc cagattttcc ggcgattgca tcagttcgag
     8341 atcttccaac agcagatgcg aatggttggc gccattcgcc tgccacagcc acatcgtcac
     8401 cgccagagcg gccatcgagg ccagcgccac ccccccggcc cattgaagcc agggccgccg
     8461 cgcagaggac cggcttacgg cattcacccg cgcacgctgc agggccagca ccgtcttttg
     8521 atcgagctcc tgcaggcggt gatcgagaag acgcttcgcc gcggctgata aaggatccgg
     8581 ctgctcgtcc gatcgttcgt tcatggccaa tgttctccca atcgctgccg cagtacctgc
     8641 agcgcccgga acaaatgggt ctttacgctg ccctcggaac accccatcgc acgagccgtt
     8701 tgcgcgacat ccagttcctc ccagatgcgc agaagaaacg cctgttgctg acgaagcggt
     8761 aaggcacgca acgccacttc cagctccgca caggcccgct tacgctgcac ctcgccatcc
     8821 ggtgccggag tgcttgaatc gggaatctgc tccagcggat cctccgcgtc ctcatcatcc
     8881 tgagccccac gaaaaaattc gcgcaggcgg tttcgaaccc gttcccgccg ataccaatcg
     8941 cggatgcgac tttggagaat gcagtgaaac agcgcgcccc attcttcttc aggccgccgg
     9001 gcatacttct ccgcaagctt caacatggca tcctggacaa gatccagcgc ctcgtccgca
     9061 ttccccgtgg caatatgcgc catgcggaat gcgcgccgct caatcccggc cagaaaccga
     9121 tccaatgcct gggtttgatc cagagatgcc accctctcac ccaggcacag gtggcctggc
     9181 tgtccaggaa cggcgatggg ggaatggcag ccgctcatcc ccatgctcgt cttctatctg
     9241 cccagtcatc gaccgatgag gccccgtagg cagcagccgc atggacccgg tatcggtcga
     9301 gatcggcccg attttcgact tgaaacacgg tgaaatcaag agaatccaag gaaatctccg
     9361 ctcgcgacgc aacgacgagt cctgaaacgg atgcgccgga ctcgcagcca ccctgcctgc
     9421 ttcacagcga gagtgcggct ctttcaggct ataacgcgag aagacaatcc cggttgacag
     9481 gatgggggca ggaccgcggc acggtgatgg gagcaacact gcgacgtatt cggtgagagg
     9541 cggggagaag aattgcggac ggaactactt ggctttgccg gtatcggcca attttttgcc
     9601 gccggcccag gccaccgagg ggatctgagc cacgagatca aggcgctcgt gcgcttcatt
     9661 gtccttgagg tccggtccga cactatacag gacgcctttt ttcatattga ccagcatggg
     9721 cagcccggta aaaggatcgt agagcccctg gccggccttg gccagccggg tcagcaagtc
     9781 ctgctccggc ggggtccggc gtaaccaggc ctgcaacgag actaaccgca accgcgcatc
     9841 ggtttccaga acccggccgg cataggtttc ccatgtgggc atggagtcca ccccgaccag
     9901 gccttcaatc ggattcatca ccatgtcgct cacgctgtac ggagccacac gcacaaactg
     9961 ggagagcttc ggcaggtcgg tataccgtcc gtcggctgcc gcttttccag ccgcatcata
    10021 atattcggcg taggcattga accggcgttg cttcggcagc ggcaacgccg cagcgatggc
    10081 gccatagaac gggcgcgtct cggcccggtt ctggctgacc gcctcatcca acgtcttggt
    10141 agcgagcaca aattggctct gcatcggcca acggagggac tgttcggacg gctctaacgg
    10201 cttcgccaat ttcgccatgc ggctcacata tcgttcatcg agatccggcc gctgcaagag
    10261 cccgtccatg atcatcgcgt cgtcattcat tgccgcactg gccagcattt tcaccggcaa
    10321 cgacttcgcc tgtcccaaga ccgtccgcca ggccgtgaga tcggtttcca gccgcgcgaa
    10381 ccccgtgtcc acatcctgcg caaatccgtc ggcaagatac agtcgatgcg tctggaggat
    10441 gagcccgcag ttcggactga tcgactggcc gtatcccaca tcttcaaacg gcttgttcaa
    10501 ccattggcgg tagcggctga ggccgacttc cgcttgcgac agccacgttt tggcgccgct
    10561 cacatccatt tgcatctgca acgccggatc ggcagctttc atccacttgc ccgccgcgtc
    10621 ggccgaggca ctctgccttt cgtcgggcga atacccttct ccggtcaagc aggtatgtgt
    10681 gaaggcacgg tcggcgcctt caatccgtcg atccaggcca acctgcacag gatcctgact
    10741 cgcggccgct ccgaggccga gcaagagcag atagccattt ttactggagt cttgcagtgt
    10801 ctgttggggc accgacgtca tggtgcgata ggctgcgttc ggttgctcct caagtatcag
    10861 ccatgtcagg gccaccgcag cgatggtacc cccaaccaca aacagcacga ggccgaccaa
    10921 agccagaacc aggacaacga gcgatcgcgt tgtcgacacc cctgctccga ccagagacgc
    10981 cgccgcttcc gccacccggc tccatactcc gcccccggcc gattggatgc gcgtgggacg
    11041 atgggtcggc tcttccacaa ctgccgcagg agcttgctcg atgtgttcat acggctgctc
    11101 catcacgact gcaacaggaa cggattcctc cactgcctgt gaggcgaccg gcacgacagg
    11161 ttcagccggt acgggagtcg ccgggggaac ggcgctgact tcaggggcaa caggctccgc
    11221 aggctttttg agccagcgag tcagcatatt tccagtggaa ggtttcggtg tcggtgctga
    11281 cgaggcatct tcccacaaaa tatgtaatcc atcgcttgcg gggacctcag ctggagcgga
    11341 gacagccggt gcaggcacct ctggctccaa agcagggacc ggggaggcag ccatgtctac
    11401 aggctggtct gtctgcacgg cctcaagagc ctgggggatc tgaacaagct cgctcgactc
    11461 ttctgccggt acaacggtcg acagctcgtg cggggccacc agcggagcgt cttcagctga
    11521 agcagttggc acctccgtca actctgtgag cgacacctcg gcggccgtca ccacagaatc
    11581 aactaccaca tgctcgtccg gctttgcggc cggctccagc gcaagaaccg gtgcaggctc
    11641 actctcctcg gacgaaggct ccgccggcgg ttcaacctgt gcctcgagag caatcggttc
    11701 agccagggaa accgtctgct cttcaacaga agacaaggga ataggctcga cgatctcgtc
    11761 taccggtgca gagcctgaag gcatcatcgc ctccggcgca ccgactaact ccagcgagtc
    11821 ctccacttga ggtgcagcct ctaagaccgt ctcaatcgat tcagcaggcg ttccggcgag
    11881 agtgaattcc gtgatcggct ccgctttgac aggnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12001 nnnnnnnnnn nnncactggc tccggcaccg caggcacaac gagggtggaa tccaatgcca
    12061 ttccactaga gttcccggtt tcttcgactg cgatggtggc cgaaccaaat tccggttccg
    12121 gctcttggcg gggaatggcg acatcttcga cttcgacctg ttcccagggc atgggcgccg
    12181 acaacgtcga tgaggcgctg ccgagatcca aagagggttc ggacgagggc gcgtctggag
    12241 cgaccgccgt catctccaca gcatccgagg gcgccgtgac tgcagtagcc ggctcttcca
    12301 tcacagtgga ctctgttgcc ggcgtcggtt ccgcgctggg aagcgactgg ggcgacgcag
    12361 gagatgattg catcgcggca accgctgcaa gaatttcgtc ccaggacagt ccggatgacg
    12421 tgatttccga ggaactggag gcggaggggg ctgccgtctg cgcctctgcc tgctgtgcgg
    12481 gaggctctgt atcggacttt cctgcctcga tcactggcgg caacggcgtc tcttcacatg
    12541 ttgccggcgc aacctcctcc acactgggcg cggaagaccc tgccgccgga ggaatgagaa
    12601 tggggttctc ttcgacctga tcccagggca tcgacaccgg agtcgtcggt gtggagacga
    12661 tcgggtgact gcctgattgc gacagcactt cgattgcgcg tggagcagga tcactaggag
    12721 gagccgatga ccattcagtt tcagaggtcg gcatctgcgc agactctggc acagccgata
    12781 cctcactcgt aaccggcggt atcgcgatga tctcctctgc aacctgattc ccagacagag
    12841 gagcaggcgt caagggcgta gaagccgttg tctggctgcc ggtccctgcc ggcagttcca
    12901 tcgagggaag cactgcctca acggtgacgg cgggtccgac ttcagattca agggcaatcg
    12961 gagccacttc gtctgaaacc gtcgattcct gactcggaga tgcgggagga atgacgacgg
    13021 cgacctcttc aacctggtcc cacggcatcg gtgccgggct cgaaggcgca tgcgcaatcg
    13081 gatcggcgcc gacctcgacc aacgccacgt tcgtcggcgg aagctccaca ggaatcgtgg
    13141 gaggcgctga ttccacctcg ccgctcaacg cggggagcgg atcgatagca ggcggttcgc
    13201 tttcagctgc ggccttcatc ggctcgtcgg aggagccaac tgcgggcaca gcaggagcaa
    13261 cagaatccgc cgacgtcaga gtcgtacgca cctctgatga ttcgagcgtg gggctttgat
    13321 caatctcggt cttttgtgac tcaaccgctg ccacagcctc gactggcaat gccgcagaca
    13381 gcgccggctc gatgacttcc gctgtcggcg gcacgtccga tggactggac ggggcctgag
    13441 cgacaggcac atcagcctgc aggggctcga tctgttccca gggcatgggc gcgacagcac
    13501 tggccggagc ttctaccccg tcagcctgag gtgcttcgtg ttcctgggta ggaaccgcag
    13561 gctgaggggt agcctgcaat acttgccccg taacagtatc gaacatggcg gcaaggcgga
    13621 acgagaccgg actcccggga gcgatcgagc gaatccgtgc gaaaagctcg ctggggtggt
    13681 tcggcttctc ggtgtcggga tcctccagca agacttcaac cgctttgcca tactcggcca
    13741 ctgccgccat gacgtcgcct ttttcctcgt agacgcgtcc cagcatttcc aggaagggca
    13801 cgtaccgcgg ccctgccgtc aggtattccc gcaacagcga ctcggccagc caataatcct
    13861 gccgctccat ggcctcccgg gccagggatt cgaacgccgt cctggcgctc atgaggcttc
    13921 caagccgcag atggagggtg gcgaagaggc gcctggcttc agcgttgagg gggtcgagcg
    13981 ccagcaggtc tttgagggcg gaggacgcac ggccatactt gccggcgttc atttgcgtaa
    14041 tggcgtcctc gagcagcgcg gactttttgt tgtagccgag gctgcccttc ttctggacct
    14101 tggggagaac ttttttatcg gacttcaggg gaggtttttt atcggatcgc actgtataac
    14161 cctataactt tacacgcatc cgagaatggt atggaccggc tacgggtctg acgagtccat
    14221 ggggaacctg acagagccat gtgccttacc ttttcggcat tctttcgtgc gatcttgatt
    14281 agggattttc ctgtgccggt tttgacacag agacgagaga gatnnnnnnn nnnnnnnnnn
    14341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14401 nnnnnnnnnn nnnnnnnnnn nnngcgatct tgattaggga ttttcctgtg ccggttttga
    14461 cacagagacg agagagatcg accttggaca ccctgtttga ccggcgggga gacttccgta
    14521 tactgcggca gggagaattt gaccgatatg cagcgcatcc tcatcttttc tgacctggac
    14581 gggagtctgc tggacgccac aacctactcc tacaaagacg cttcggatgc cctggcagcc
    14641 atcgaacatc gcggggcgac gctcatcctg gtctccagca agacccgtgc ggaaatggag
    14701 ccacttcgcc gctctttgtg caatcaccat cccttcatcg tcgaaaacgg cggggcaatc
    14761 tatgtcccca acggcacgtt tcccttcccc cttgagggag cactctcgcg cgaagctttc
    14821 caagttttcc aactcggagc tccctatgcg acacttcgag cggcgctaaa ggagattggt
    14881 caagaaatcg gtggtcgatt gcggggattt ggggatctga ccctggcgga ggtggttcag
    14941 ttaaccggaa tgtcggctgg agacgcacag ttggccatgc agcgggagta tgacgagccc
    15001 ttcgtgatgg atggcgacgt cgtagcgtgg caggatctac ttgcagcggc gaccaggcgc
    15061 ggtctctgct gcacgcgagg aggccggttc taccacttga tgggcgcgaa cgataaggga
    15121 atggcgagcc gacaactgat tgaatggtat aggaggctcg agcaacagaa ggggcagact
    15181 ctcgtgacgg tcggcctggg agacagcctc aacgatctac ccatgctgga aagcgtggat
    15241 tatcctattc ttatccaaaa acctaacggc tcctacgacc aggacgtgca gctcccccgc
    15301 ctcatccgtg ccgatggagt cggacccgtt ggatggaatc gcagcctgat tgatctcctg
    15361 ccgactctct gacgatcgag tctacgacat cccgctccag ccaacccaca tgagatatga
    15421 gtgagggatc aatgcccgcg ctgagacgta ttggtccggc ggctcaacag gccgaccacc
    15481 agccctcctg caaatcccgc gctgatggcg caggccacaa gcccgagaag cgaacgattg
    15541 aacacaaacc ggctcgggcg gcggtgggga taccgcggca ccgcagcttc cccacccagc
    15601 cagcgtcgcg ccttggcctc gccgtcgata tccgaaatct tattcgtcat accatgtcct
    15661 ttatcagtga acagccaaga acgctcagcc gttagagatg ccgtaagtca tccggtgcgc
    15721 catctcgagt tcgaaccgac agcccgcgct cgagatagtc tttggccaag tctttcgcgc
    15781 ctaatccgaa ggcaatcgcc ccggccatga cgatccctcc cagagtaatt ccaaacccga
    15841 cgaccacgat attttgcgca ataccgagct gctccagcgc catggccacg gctagcaatt
    15901 gaatccccca ccgggagcag gtcgccacta atcgagcagg aggcaatccc gcattgaccg
    15961 cggcgatcag caccgcctgc gacacaaagt tggacaacaa ccagcccgct accaaaatga
    16021 gccctgccgt gaccaaatgc ggcacatagg ccaaaaacga cttggcgaaa tcgttgatcg
    16081 gttggagatt cagtgcgccc agcgcggcca cggtggcaaa aatcataacc aaccaatagg
    16141 ccgcttgccc caccaaccga gacggatccg tcttgacccc gcctcgcaac aaagcaccgg
    16201 tcacgcccag tcgatcaaac aaccgatcca acccgaccac gcggagcagc cgctcgagcg
    16261 cctggctcgc cgtccacgcg accactaaac ccgcaaagaa aatgatggac atggccagca
    16321 ggctcggcaa caccgcgagc acctgccgcg ccatcagctc cagaggatca aggagcccct
    16381 tttcgaagaa ttccttcata cttccctcct ccggcctcga ctgcagcctg ccttcagatg
    16441 gatggattca tgactctcaa ccggcatgcg gttcgttcca gcgcgccacc aagtaggact
    16501 tatccttttc gaacgcctgg cacagcgctt caatgcggcc ctcggcctcg ctcgacgtga
    16561 gcccctgagt atccaacaca aacgaggcgg tccggcccaa atataagggt gtgaaggctt
    16621 tcaacacgtg atcgagaggc aggacacgat tccgataggc gacagctgca tcgtagacca
    16681 cccgcgccca tagactgtcg gcaatccgaa aatcctgtaa ggaacaggtg ccaagtggcc
    16741 gcaggctctg cctggttccc ggagcgagaa tctggtccca aatcgtaccc aaatcagtga
    16801 ggccttgccg aaaggtgctg atcatgcgat cgacgttgac gttgaccggc tcaacgccga
    16861 cttcgtactg gaacccgaac aacggcaccg cgttcgaacc atctattttt ccccacactg
    16921 cataatgatc ttccatcagc gcgaacactg caccgagcac ctgcacgagc atagccgaaa
    16981 gatcagccgc cgggtctttg gggttgtgga ttttggcacc gagaaaactc tggcagaccc
    17041 tcgccccgct ggcgatcgct tccgtcgtca tccagatgtc gatgccgaac tttgcgactt
    17101 ccgactccca gacgtgcttg tccaggtaat gctgcgccaa ttggcctgaa aatccgaaat
    17161 ccccgccaat cggttgcctg atccgatgcc catagagggt gcgcgtcaat ggatagacga
    17221 tgctgttcgt gatggtgccg tcatatttgt gacggagata gtagggcgcg acgtagtcga
    17281 acccctgctc aaagaccggg ctcaccagga gctcgatcca ttccggcgtg atgcttcgca
    17341 aatccgaatc caccacggca caggctttgg ctttcaaacg acgggcaatc tcaaaaatcg
    17401 tgcgaaatgc gctgcctttt ccggggatac cgtgataggg cgtaatgatc ttatgaagcg
    17461 aactctgctg gtcgccgata aacagggttt tgaggtcgac aaccgcctgt gagaccacct
    17521 gctgcgtgcc atccgttgag ccgccatccg aattcaccag gacggcacgg gcctcgggga
    17581 aatatttggc caggccggcg ctgaccgctt tgacgacatg gccgatcgtt tccacattgt
    17641 tgaagctggg aataccgacc aaaatatccg tatgggcgaa ttggtcgact tgcgcctcgg
    17701 tttcaggcgt gagcggggtt gtatgggtcg cgtcaggaag ctgagggcca ggagtcatac
    17761 gtcaatctcg cacgcctccg ccctagcaac actgttatga catgaccgaa atggaccggc
    17821 gaaaggctgg tgtgtgtgac aatgtgtctt ggctaagaga caccatcttg cccaacgatg
    17881 tcaagcaatt cggcttccca cctgacatca gggcatctct accagagcct atcagagcct
    17941 gatcgatgca gagcgacgcc gccttcgatg atcggagcgc tcattttcaa aatctggctt
    18001 cagcggaatt tcgacacgat cgaggagtga gggggaaata gtgttcaggg agtgagggaa
    18061 ctgcttaccc ggcatcagaa atgacgattt gttcctttcg atccgtactg aacgacggca
    18121 ccgtggtgtg ggcactgacg aaatcgctca atcgcagctg atcgtcggca tccatgagta
    18181 tgggatcgac tccgagccgc gactcactcg cccaccgtat cgtagccaac cgtaccgaca
    18241 ggggcttggg ctctcccgga atatgcagat gcaattgaag gaggtccccg gcttgcagtc
    18301 ccttgagtcc ggttcgcgac catcccggaa tggacaggtc aagcatccgg ccgttccaga
    18361 ccagcaaccc gtcctcggaa cgtgagccgg tacattcgac gataaaccgc ggacgattct
    18421 gttgttccat cattcctcca gccaaacgcc tcggcagaat atgaaaaaca acagattgtg
    18481 ggatagtccc cgaaagtggg ggatcaacgg aaacagaggg tgcggtggag tgcggcgatg
    18541 agcgacaagg cgggcacgct acggaatctc tttttcaagc tggacagtga ggccggacga
    18601 caagcaacga ctcgattaac ctatgccacg cgggaggaat ctgctgattt caacacgctt
    18661 tcgacaaact tgtgaatacg cgcttcagcc gcggcactca acttcagggt ttcaagcccg
    18721 aatgcacggt ccttcaccca cttcacggtg acgccttcca catcaatcgc cttcggctca
    18781 tcgggcaaaa agacgcgcaa cgtcaatttc atgccaaccg tgacgggttt atccccttcg
    18841 atccgccaac ccctgacgga gagatcgcac actttgccgg ttccaaccag gccctcccca
    18901 agataataga ggaaacagct gacaggcacg cgagaatggg atcgggtcgt tggtgatttg
    18961 gccatagtgt gagcaaaggg atgagcactg cgcgcatcaa ccttgactag ggaccagtct
    19021 acgcaattcg ctgacaagga ccaagcagat tttcgttccc gacaaggcgg acacctattg
    19081 atcacgcact gatcgagacc atgaaggagg ataggatagg ctagactaac gccgtcacga
    19141 actgttcgag gcgggcctgc tcatcagcct tgatcgtgtt cacttcaacg ccgaattcct
    19201 ggccgcggga ccaacggaca atcgcgcggt cgacaaacac ggttggatgc tgaccgggaa
    19261 gaaagataca gagggtgacg accgttccag ggtctaccgg atgtgtccca tcgacgcgcc
    19321 acccattcag ggaaaggttc caggcgatac cacttccctg gaaggcatca caggaataat
    19381 acaccgagca ttggacggga aagcgacgaa aggatcgcac gtggaatcgt acaccagcca
    19441 cagaaagacg atgtgggact gacggtacga gctgcttatt gccagcaggc atggtatccc
    19501 cactcgaacc ctgctcctcg actacgttgg ggtgagtgac gggtttcgaa cccgcgacct
    19561 ccggatccac aatccggcgc tctaaccagc tgagctacac ccaccgtaca aggtcagcag
    19621 agagcgcgca tcttaacaaa ccctgcagaa cagtcgcaac cgccctcatc gcctcaatcg
    19681 ctggagcaca tcttttcgga cctgctcctc aaaagtcacc tgatctccgc tatccccgat
    19741 gatcaaacgc cgcttgcatt tccttcagga tggctgctgt cgccgcggga ggatcttgcg
    19801 cgtcacgaat gggacgcccg atcaccagat agtctgcccc ggcggcaatg gtttgagtcg
    19861 gtgtcgtggg ccgcgcgtga tcatcagtag cattgccggc cggcctcaca ccaggggtga
    19921 caatgagtaa attcggtccc accttggcac ggatcgcttc cggctcttct cctgaagcca
    19981 cgactccatc gcacccggtt tcagccgcca acatggcccg agccgtgact aaatcacgaa
    20041 cactccgctg aatacccata tcccgcaggt cgttcccgtc aaaattggtg agcaccgtga
    20101 ccgcgagcaa cttgagatcg gactgcccac gcccctgcac tgctgcgatc aacgccttcc
    20161 ggttcgcgtg aatcgtcaaa aatgtcgcgc ccatggccgc aactcgagcc gttgcgcgcc
    20221 gaacggtctc ctcaatatcg aggaacttga gatcgagaaa cacgcgcttg ccgcggtcta
    20281 ccaatctccg cacaatttca ggacccgcca ccgtgtaaag ttccaggccc accttcacaa
    20341 accgcacctg atcgcccata cgatcaacca aggcctctgc ctctgccgca gaaggaacat
    20401 ccagcgcgac aattaaccga tctcgtgcat caattcgcgt catcatcact ccaccctggt
    20461 gaccaggagg ccccgaagcc gctgatcctt tcagcatcct tgacctatct tcgtcaccta
    20521 tgttacaagc tcaagctttg aacgtaggag aatccgtatg cctgttgtcc acaaatccac
    20581 gattcgacgt gctcgccaat ccgaaaaacg ccgcttgcgc aaccgcgcga ccatcagctc
    20641 ggttcgcagc atcctccgca aggttcagga tgcgatcgcg gcgaagaaac cggatgaagc
    20701 taaggccacc ttacgtgccg ccacggcagc tctgagcaaa gcggtcacga aaggcgtgtt
    20761 gaaaccgaac acggcctcac gccgcgtgtc ccggctcgct gtgcgcgtga acgccatcac
    20821 cgcttccgcg taaccgttct gacattcgac accggtctcg atcccgatgg gcgcgaggcc
    20881 ggtggtaccg ccggttgcac ccgctgcgct gctgatgccg gtttcgacgg cttcccgcac
    20941 agtcgaaaca agagatcttc catcacacgg accggggtac ttccgcttcc gcccttcagc
    21001 ttcgaatccg tctccaagaa ccactcaaac gcttgagtca tctggtcatc cgggaattgc
    21061 gctaaaaatc cccgcactcg cgaaggatcc atccgaaacg tcctcgcagc ctcgccttcc
    21121 cgcccaccgg ctttgagttg ctccttcagc ttccaaagac gccggtattg ccagactaag
    21181 gcgccaagga tacggagggg ggcctccccg ttctcgacat tcctcgcaag aattctgaag
    21241 gctcgcccat gatcgtgtgc gccgatagca ttcatgagat cgaagaccga tgcgccgggc
    21301 tcggtccctc tgagcgcctc cacatcggac gattgtacgg tccggtctga cgggacatag
    21361 gcggcaagct tctccaactc tcgcttcact gcatagaggg actcacctcc gacctccttg
    21421 agcaactgga tcgcatcctc ctgcatgcgc acacccaacg cggccgcttc ctgtcgaatc
    21481 caggccgaga gctgagcatc ccgcagggga gcgcaattga ccgtcaccgc ccgcttcgtt
    21541 aaggcctgcg tccatttgag ccgaccgtcc aacttggccc ccaccacaat gaacgttgta
    21601 gtctcattcg gcgaagccag atacgacagc agcttttcgc cctcccgagc cggcagcttc
    21661 tccacggact tatagaccac gacgcggcgc tccgcgaata ccggaatctc cgccgcgcat
    21721 gctaagacat cggcgatgga ggagtcgtcg ccgtgaaaaa tatcgtaatt gaatccactc
    21781 tcagcgccgg cgcccagggc tgccgtgcga agcgcggcga cggaggagtc gcgcagataa
    21841 tcctcctcac cgacgacggc atagagcggc attaccccgc tacgtgcgag ggactggggc
    21901 agttccatgc tcatgaccga cgtactcacc tacagacacc ctccaacatc aacgggcagc
    21961 ctcaggtggt gcatttccac cgggaaccgc ctcggctttg acgggacgct tcaacatttt
    22021 gtccaactct ccagtatcca ggaacagcaa aaagcgagac gcaagatcct ctgccacgaa
    22081 tcgacccgcc tgttccaacg cccgattctg cagcacgcgg ttgaattgca gatcttgcgt
    22141 gagaaaaaac tccgaggtcc ccttcgcaac ctgcgaccac accagtcgct tggttttggc
    22201 atcctcgatc cgcacactca ccagcatttc gacgcggctt tcaaaggtag tggtctgatc
    22261 gaaactcaag gtcggcagta aaatctgcat gatctggccg gacagataca agtctgcccc
    22321 ggcggagggg ccgacaattt ccgcccccgc ccctgcagaa aactcccggc gcaaatagtt
    22381 ggccagctta atctcgaagt tcggctcgta ggtgctattg gagatgggaa gaatcgccag
    22441 tttcggtgcc tgagaccgct ttactgctgg ttccgacgcg ccaccgatcg taggaccggc
    22501 gccctgtacc cggaactggt agccgcaggc ggtgatgttc accgcgcaca gacccaagac
    22561 aagcaacaac aggtagcgag gcatggcatc acaccacgaa attgatcaac ttcttctcga
    22621 cgtaaatcac ctttttcggc tctttcccct gcagccattc ggcgacttct tttttggcga
    22681 gtggctccag ctggtcgcgt gatgccccgg catccacctc gagctttcca cgcagcttgc
    22741 cgttgacctg aattggaatc gtgagtcgat cgctgaccac caaggccgga tcgaacggag
    22801 gccaggcttg ttgcccggca ctcggttgat gaccgagccg ttcccagagt tcctcgctga
    22861 gatgcggcgc aaagggcaac agcaacaata cgaacggttc caacaatgcg cggggccgct
    22921 gatccaattt cgtcatgtcg ttcgtaaaca ccatcatctg tgaaatggca gtattgaatc
    22981 gcaaggactc aatatcttcg gtgacttttt taatcgtgta gtgaagcagt cgcagctgct
    23041 cagcggtcgg tgtgatattc gtcaccgcag cgctcaacgc gccgtcttcg ccgatcatga
    23101 gccgccagac ccggtcaaga aagcgggtga tgccttccac cccgcgtgtg ctccagggct
    23161 tcatcgactc gaggggtccc atgaacattt cgtacaagcg gacggcatcg gctccgaact
    23221 ggtcgatcat ctcatcagga ttcaccacat tgccgcgcga cttcgacatc ttctgattgt
    23281 cttcgccgag tacaatgcct tgatgcacca actttttgaa cggctccggc gtgctcacca
    23341 caccggcatc gaacaacact ttgtgccaga accgactgta cagcaaatgc agcacggcat
    23401 gttcactgcc gccgatatag aggtccaccg gcatccaata ttgctctttc gccggatcga
    23461 ccagttgccg ggtgtttttc ggatcgatga accgcaggta ataccagcag gaacccgccc
    23521 attgcggcat cgtattcgtc tcgcgccgcg ccgcttggcc ggagacagga tccgtcgtcg
    23581 tcaaccactc ctcgagattg gccaacgggc tttcgccgct cccggacggc ttaaaattct
    23641 ttgtctcagg caagggcagc ggcaactgct cctccggcaa tggccggggc tcgccgtcaa
    23701 cccagacgat aggaaacggt tctccccaat aacgctggcg ggcgaagagc caatcccgaa
    23761 gtttgtaatt gatagttttc ttgcccttgc cgtgggtttc gagccaggtc gtcattttgg
    23821 gaatggcgtc cacaggcaat aacccgtcga gcgaacagga cccgtccggc gtggtcgagt
    23881 tgatcacacg gcctcgctcc gtctcaacga atgccgcctg gtccacctgg ccgccctgaa
    23941 tcacctcgcg aatcggcaga tgatattgag tggcaaaggc ccagtcgcgt tcatcatgag
    24001 ccggcaccgc catgatcgcg ccggtgccat aactcatcag cacatagtcg gcgatccaga
    24061 tcggcaggcg ttcatgattg acgggattga tggcatagcc acccgtgaag acgccggttt
    24121 tgactttatc caattcctga cgttgcagat cgcttttgcg ggcggccgcg tcgcgatagt
    24181 cagccacctg tgcccgctgc gacggagtcg tcaccacatc gacaagggga tgttcaggcg
    24241 ccaccaccat gtaggtcgca ccgaacagcg tatcaggccg ggtcgtgaag acacgcagat
    24301 ttcctgtcgt gtcggccagg gcaaaatcaa cttcggcgcc gatcgagcgg ccgatccagt
    24361 ttttctgcat ctcgagcgta ctggtcggcc attcgaccag gctcaaatcc tcgagcagcc
    24421 gctccgcata ggcggtgatc ttcaacaccc attgccgcat cggcttgcgg atgacatcga
    24481 atccgccgac ctcgcttttg ccatcgacga tttcttcgtt cgccaacacc gtcgacaacg
    24541 ccggacacca attgaccgga acctccgcca cataggccag gccacgctcg aatagtttca
    24601 ggaagatcca ctgcgtccaa cgatagtagt cctgatcggt cgtgctgagt tcgcgttccc
    24661 aatcgtagga gagccctacg cgtttcatct gccgcttaaa cgtcgcaata ttttgagcgg
    24721 tggtgatggc gggatggaca ccggttttca cggcatattg ttcggccggc aagccgaacg
    24781 catcccaccc catgggatgc aacacgttga agccgcgcat ccgtttatag cgggacacaa
    24841 tatcggtggc ggtataccct tccaggtgcc cgacgtgcag cccggaccct gatggatagg
    24901 gaaacatgtc cagacaatag aacttaggct tcgaagggtc atccgaggcc cgaaacgggc
    24961 ggtgggtctc ccagtaggcc tgccacttcg attcaacagc ttggtgatcg taggatttgc
    25021 tcatcgtatg aacatcatag gtgacgtagt gattggcgtt cgactgaaga acggacgact
    25081 gtagcatacg cggtacgcgg caacaaggac gccgcgggag ggattctgaa tgggcacgtc
    25141 cgcttcgctt gatccgcagc gccactcctg ctcaaataca cggcgagacg gcagcaagag
    25201 cggcactaac cgcgtccatc ttcccggcga ggaatgccct tgagtatcta cgccacctac
    25261 atttttcccc ggctcatgga ttgggtgctc cgcggagagc gcttccagac cgaacgccgc
    25321 ctcgtccttg ctccagccca tggaacagtg ctggagattg gctttggtac agggctgaac
    25381 ctgccgcact acccgtcgac catcacggac ttgcatacgg tggagcctgc gacgcttttg
    25441 cctgaccgcg tcgcccggcg ggtggcgaac gcgccctttc ccgtccacct tcgccagctg
    25501 agcgcagaag tgttgcccta tgcctcgggt ctgttcgatt gcgccgtcan nnnnnnnnnn
    25561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnc agctgagcgc agaagtgttg ccctatgcct
    25681 cgggtctgtt cgattgcgcc gtcagcacct tcaccttatg tacgattcca gatccctgcg
    25741 ccgccttgcg agaagtccgg cgagtcctga aacctggcgg ctgcttcctg ttccttgaac
    25801 acggccgaag cgatgaccct gcgatcgccc gctggcagga ccgactcaac ccgctgcaac
    25861 aggtggtggc ctgcggctgc aatctcaatc gacgcatcga tcgcctcatc acgcaagccg
    25921 gttttcgcgt ggaacagctc gatcgtttta ccttgcccgg cgtccctcgc atcggcggag
    25981 agatgtatcg aggcagggct ggcaccgcgg gtcgctccac gtagtaattc atatgttaca
    26041 gggaaattgt atccctcccg ccaattttgt agactgcgcc tatacaagag tgttttgcat
    26101 gtattcttct cgtaaacggg agtgatcccg atggccgtct cccagatgtt tccgggcaac
    26161 catccctcct caacctcatc gtccgacccg atcgattcag tcagagagac cagcctggca
    26221 tttcagcgcg tcgccctgct ctatcaggcc atgcccgcgg cgctcattgc cggcctcgga
    26281 tgcgccgtcg cgttggtctt cgtcaattgg aacgtcctgc cgcatgatcg gttgctcgcc
    26341 tggctggcgt atcatctgct cttatcgatc ggtcgatatg gactggctcg ttcgttcgcc
    26401 gctacatcgc cgacgccctc gacgatacga cggtgggacc gggccttcct gacgggaacg
    26461 ttgctggccg gactcggttg gggcgctacg gcccttctcg tctttcccga atcgtcactg
    26521 gctcatcagg tcttcctggc ctttgtgttg ggaggcgtgt ctgcgggcgc gtcctcgacg
    26581 ctggcggcgc gattcgatgc gtttctgtcc tttgccgttc cgaccctggc cccgctgatt
    26641 ctgcggttct ttttcctcaa ccatgagcaa gccctgccca tggccatctg cacgctgctg
    26701 ttttccctgc tgatggttta tacggcatac cgaacctcca acaacgttcg ggagatgctc
    26761 cagctcaaat atcacaacgc acaattagtg gatcagctct cgtcgcaatt ggaagaggga
    26821 gagcagactg cgctgctctt gaatgtgcac agcgagcact accgcttcat catggaatat
    26881 gcgcaggaca tcatttatcg aaccgaccgg agcggccggt ttacgttcat caatcccgcg
    26941 gttatccgcc tgctgggcta tcacgagacc gaaatgctcg gtcatcgcgc gctggatctg
    27001 gtgcacccga actaccgccg cagcacagaa cacttttata tccgacagtt tcttcgaaaa
    27061 actcccagca cctattacga attcccgctg ctcacgaaaa cgcatcagac cctgtgggtg
    27121 gggcaaaacg tccaactgct gcttcgggac caggaggtca ttggattcca agccgtgatg
    27181 cgcgacatct cggctcgtaa agaaaccgag gaagccttgc gcttcagcca ggaccgatac
    27241 cgggcgctgt ttgagagcag ccccgaaatg ttgctgaccg tcgatgcaga aggccgatta
    27301 ctcacggtga atgcgacggc cgctacggaa ttgggatata gcgccgacga attggtcggc
    27361 cagccgattt cattgatcgt gcacgccgac gatcgttcca ccatccagca acattttgca
    27421 gactgccttc gacgaccggg acatgtcctc cgcggggaat tcagaaaaat ccgcaaaggc
    27481 gggagcccga tatgggtacg agaagcctcc agagccgtgc gcaacccgaa cgggcagttc
    27541 gacatcctga tcgtctgcga aaacgtcacc gaacggaagg ggatggagga cgcgctgacc
    27601 cacacgcgcc agctcttgga gtccatcgtg gaacacattc cgcacatggt cttcctgaaa
    27661 gatgccaagg agctccgctt cgcccagttc aataaagccg gcgaacaact catcggcctc
    27721 ccacgggaag ccctcctggg gaaaaatgat ttcgatctct tcccccgtga acaggcggag
    27781 ttctttaccg caagggatcg ggatgtgctc acgggcggag cccttttgga cattccagcc
    27841 gaaccgatcc agaccaagga tcacggcctg cggtggctgc ataccaagaa actcgccctc
    27901 tacgaccaca ccggcgtgcc tcggtatctc ctcgggattt ccgaagacat cacggatcag
    27961 aaacagcggc atgaaatcga gcaacgccgg ttgggacaac tcgccaccca acagaccgtt
    28021 ctccataaac tggcagaaga tccgtccatc cacagcgggc atccccaaca ggcgtttccc
    28081 gtcatgaccg aacacgcggc cggcacgttc gcggttgagc gagcgagcat ctggctcttc
    28141 gacggcaccc agtcgacgct ggttctacaa gacttgttcg aggcgacctc caaccgccat
    28201 agccagggaa ccatgctttc taccaaagag tacccggcct atcttcacgc ccttgaaacg
    28261 gagccctatt ccttggccgc ccatgcggca caatctgatc cgcgcaccag cgaattgacc
    28321 ccttcatatc tcatcccgct tggcatcacc tcgatgctgg acgctcccat tcgccgccat
    28381 ggacgtgtgg tcggagtcct ctgcctcgaa cataccggca cgcccaagac ttggaccagt
    28441 gaggaggaag cgttcgccgc ctctctcgcc gccatggcga ccctcacctt ggaagcagcc
    28501 gaccgccggc aggcgcagga ggcgctggaa caacatgtcc gcgagcgcac gggcgaattg
    28561 cggcgcatga ccgcgcattt gcagaccatc atcgaagaat ctcctctcgc aatgattgag
    28621 ctggatcaca caggccacgt cacgacctgg aatgccgcgg ccacggcctt gttcggttgg
    28681 accagggagg aagttctggg caaggagctt ccctatgtgc ccgcgggtca ggaacaggct
    28741 tcgaacgagt tgtggacctc tgtcatgaac ggcggcgcgc cgcgcaacct cgaactctgt
    28801 cggcagcgaa aagacgggac cttgatcgat gtgaacatgt ggggaacgtt gctgcaaggt
    28861 cccggcggcc agacgaccgg gtcgatcggc tttttcatcg acgtcacgga gcacaaacaa
    28921 ctggaggaac agctccggca agcccataag atggagggga tcggcagatt ggccggcggc
    28981 gtcgctcacg atttcaacaa tctgctcacc gtcatcaacg ggtgcgccat gctcctattg
    29041 gaacaggtgc gcgccgaaga ccccctgcat cgatcgctga ccgaaattct gaccgccggt
    29101 cagcgggcgg ccgcgctcac caagcaactc ctggccttca gccgtcgaca ggtcctgacg
    29161 ttccaggttt tcgatctcaa tgaggcgctc tcctcgatca gctccatgat tgaacgattg
    29221 atcggcgaag atattgccct cgtgagagac ctcacgtctc agccctgcat catccgcgcg
    29281 gaccggggac agatcgatca ggtcgtgctg aatctggcgg tgaacgccaa ggacgcgatg
    29341 ccccacgggg ggacgctcac gatggcgacc cgaaccgtga ccctgacggc agacacgccg
    29401 gtcccccatc ccgcgatgct tccgggtcgg tatgtccacc tttccattcg cgattccgga
    29461 gagggaatgg accggaccac cctctcgcat attttcgaac cgttcttcac cacaaaggag
    29521 gagggcaaag gaaccggcct cggtctggcc acggtctatg gcatcgtcaa acaaagtcag
    29581 ggctttatct tcgctgacag caaccctggc gacggcgcca cgttcgacat gtatttcccc
    29641 ttggctcagg ctccatcccc ggccgctgct ccggccactc cctcgcgccc tcactgtggt
    29701 cacgaaacca ttctcctggt cgaagatcaa acggccgtcc ggatgctgct cacgcaggcc
    29761 ctctcggact atggatacac gttgatcgag gcctccagcg ggcaggaggc acttcgcctc
    29821 gtagccgccg ccaagacgcc catccatatt ctcctcacgg acgtcgtcat gccgcagatg
    29881 acaggccctg cgctggccga acgcctccgg cagcaatggc ccagccttcg cgtactcttt
    29941 atgtcggggt atgcggaagg gagtgtgttg ccgacgttcc tggcagaacc gggaaccggc
    30001 ttcattcaaa aaccgttttt accgacggag ctcgcccaaa aacttcgcga actactcgat
    30061 tccgccaagt agccactcgg tgagtgacac gggtgcgcga gcgccacgcc cgtgaatcac
    30121 ccgggcagga tcgattggaa attttcgatg gagtggaatc gtgcggaagg aaccggcgag
    30181 gcttgagagc tcgacttcga gcgatgaaag atccggcgga tgccgaactg ttctgccgcc
    30241 gcgagacatt gctcgtcatc atcgatatac aaagcccgtg acggatcgaa gccgaccagc
    30301 tcctgacagg tcggccagta ttcggagcgc atcttcagcc atcctacctc gaacgcatcc
    30361 acgatgcggt cgacctgccg gtgtagaccg gttttggcag ttttgacctc aacgcccgcc
    30421 cggtgcgcgt tcgtgagaat cgtgacccgc ttttcgagcc gccgcaacga caggagaaac
    30481 gcctcggcat cggggaggaa tccaatcatg tggtcgagtt ctcgatgcat cgccaccaca
    30541 tcgatctgta cctgctcggt ccaataatgt agatcagtcc aggcgagttc gccctctaca
    30601 gaacgataca tgctcatcag tcgatcccgg gcttccgcga aggccaatgc atgtttcgcc
    30661 gcgtaccgtc tgggcagttc ttcttcgaaa aaaaagttgt cgaaatggcg gtccaggagc
    30721 gtgccgtcca tgtcgaggag gacatcgtcg atgtgactcc aatcgacggg atgaggcgtc
    30781 gggtccgtgc ggtgctgcag catcagttca gtataacgga gaccggtaag acaagacgag
    30841 tcattgtgtt caacgaaatt tctatgttac cgtcgcaggc catgtcacgc accaaacccg
    30901 ctcgtggtcc cgtcacaccg ctcttcacgc tggaaggcgg tcgcctgccc attatcgccc
    30961 tcgtggggcg tccgaatgtg ggtaaatcga ccctcttcaa tcgcattctc ggcacacgag
    31021 ccgccattgt ggacgatgtg cccggcgtga ccagagatcg caactatgct gacgccacct
    31081 atcgcaaccg ccatttccgc ttagtcgata ccggcggact cgatccgacg gcctctgaag
    31141 gaatgttgtc gctcatccgg caacaatctc aactcgccat cgcggaggcc gacattctag
    31201 tcctcgtcct cgatgctcga gccgggctca cgccgcccga tgaagaggtg gtcgcgacgt
    31261 tgcgcggctc cgacaagccg gtgttttatg tgatcaacaa ggtcgatacg cccaaggccg
    31321 atccgctcgt ggccgacttc tatcgcctgg ggcaagagca cctgtacccg ctctcagcgg
    31381 aacatggtat cggcgtggcc gaattgctcg acgatttgtt tccccatatg gtcgacccgc
    31441 cgggtgaaga aaccccgacg gaaatccccc gcattgccat cgtcgggcgt ccgaacgtcg
    31501 ggaaatccac cctggtcaat tcagtactcg gcgaggcgcg ggtcgtggtc agcaacgtgc
    31561 ccggaaccac ccgcgatccg gtggactcga ttgccacctt taaagatcgg caatacgtcc
    31621 tgaccgacac ggccggtatc cgccggcgag gccgtgtcga acgcgggatc gagggctaca
    31681 gtgtggcgcg ctcccttcgg gccatcggcc ggtcagatgt cgcggtgctt ctgctcgacg
    31741 cggaagaagg tgtgacggaa caggatacca agattgcggg cctcgtcctc aaacagggtc
    31801 gcgcctgcat tctcgtcgtg aacaaatggg atctcaaggc cgatgacgtg gatgctcgag
    31861 aagcgtacaa acaggacctt gaacgccgct ttccgtttct cgcctgggcg ccggtgctct
    31921 ttatctcggc gctggagcag gatttcttgc gcggcctctt cgcattaatc gatcaggtct
    31981 atttctcctt ctgcaaacgg gttcccacgg gggcgctgaa ccagtttttt cagggtctgt
    32041 tagaagaaca cccgctgccg gtgaggaaag gcaagccggc caaagcgagt aaatcggcgt
    32101 ttgtgacgca agtggccaca cgtcctcccg cctttgcgct gttcgtggga catcccgaca
    32161 acatgacgcc ggcctatctc cgttttcttg agaaccaaat ccggaaggaa tatcattttt
    32221 ccggcacccc catccgtttg atggtccgca aaaaatagtg cgcgggagac agcatcgcag
    32281 accgtggcgc tcctgctaca gtccgtcgca tatcccactt cctgaatgac ctacatagag
    32341 gtcccgaagg cctttcaact tgactcatgc cgaccagcat gttattcgca caggagacgt
    32401 tgtacgccac gtacgatccg gcagaaccgg ccattcacta gtaatggccg gtttctcccc
    32461 cgctcaatcg gcgtgaaacc attccacacc gcatcattcg atacacatta tggtaactct
    32521 cgtgaattcc gaccaacgat tccgatgcat ttccctctcc ttgagtgcgc tgctttctct
    32581 gagctgcctg cccgcagcag gctgggctga accctccgcc ccgctcatcg aaccacctcc
    32641 actcgaagag ccggctgcct cagttgaacc agttgcaccg gaggcgcttc cggttgaacc
    32701 ggaaccgacc cagaccgtgg ccactgcgcc cgtttcccct tccgtgcaag tatccggttt
    32761 catttggaga tccaagccgg gaatcgtctt tctccaaaca ccgatcggac ctctttctct
    32821 gagttcaaaa acgacgctgc gcgacgtcaa aaattcgcaa aagatcacac tctgggttca
    32881 tggcacgaca acagtcattg atatccgcga gaggggggcc gacaagctgg tgcatcggta
    32941 tgtgacggcc atgcccaatt tcacctcccc cgaaaaacag acggtcgcgc tctggacccc
    33001 tgacggcgag caatcgttcg ccctcggcgg gctcgcagcg aaaattgcca gccgttcaga
    33061 cgaacagcct tttaccatcg aggtggatgg atccggcacg gttcgcggcc tgcatgacgt
    33121 gcaatacgat cttcaagtga atcaggttcc gcgcacacca tcctccgtcc atcttctctt
    33181 gaacggcacg gtttcgaagc taaagtcgaa ctatgtgttt ctcaaaaccc ctctgggaat
    33241 cgtcaccgtg agcgggaaaa ccggtgtccg caacgccaaa gtcgggcaag agatgtcggt
    33301 gtgggtgcag gatcggcacg tggccatcga cctgtatcaa gacggtgtgt ccactccatc
    33361 ccgccgcttt ctctccggcc cgttgaccta tgcgccggaa gggcagagcg cactgatcat
    33421 gcagggaccc gagggcgcac agtccattcc gctcgcgcaa cggccggcgg ccctctcggc
    33481 cgtgaaggaa ggcttgccga ttacggtcga actgggccgg caaggcgaac tcctcgacgt
    33541 ccggcgcgtc aattagtcat cgccatcaac gtgggtgtcg acccggccgt tcgcttgaca
    33601 gggtctgaac accacccgta gactcgcttc cgcgtatggc atcacggaag aaaagtccgc
    33661 cggcgtcatc tgatgggcac ggcctgcccc actccgcatc ccatccattc gaccaactgt
    33721 atcgagacca tgtcgacgtc atgtaccgct ttgcctatcg gctgtgcggc gaagccgaag
    33781 cggccaaaga tctggtccag gaaacatttc tcaacgccta tcgcgcctat gatcgctttc
    33841 gcggggatgc gcgcgtgtcg acctggctct atgccatcgc ctcccatgcc tgtcagcgca
    33901 tgcgccgaaa acgcaaaggc gaaccggaac gcgagctgtc gctgaccgaa ttcgtgccga
    33961 cgtcggaagg cgagtttgcc ctacagatac caatggaggg actgagccct caggaagcgc
    34021 tcgagaataa ggaactgcgc gagatcttag accgggccat cgccaaatta ccgcgcaagt
    34081 atcgtatggt cctcgttctg cgcgacatgg aagggttgag cgccaaagaa gtgggcgaca
    34141 tcctcggatt gagcgagcgc gccatcaaat cccggctcca tcgagcccgt ctgtttgtca
    34201 gaaaagaact cagtggaaaa gggctcgcgg aggaatttca ccacgcggtt accactgtgg
    34261 atcgatagtt tggtatagtc aaagaagcag tatgaccatg gcagaccgcg tacgcacata
    34321 tccaggcact cgcaagccca ccccgcatca gggtcaccgc aaacggaatt gcgtcaaagt
    34381 tctggaacgc ctttcagcct atctggacga cgagctgtcc ggcgagatct gccaggaaat
    34441 ccgcgcgcac ctcggcgact gcccgaattg cgaaatattc ctcgattccc ttcgccagac
    34501 ggtccggctg tgccagcatc ggccctcccc ctccctctct gagcacgatc gagccgcact
    34561 tcgacgccag atcttaaagg ccgccgcgac ggtgtgagcc atcgtgacgc gtccgaatcc
    34621 catcacggct gtgcctgagc cgtcggcaac tgattccctc tcacagactc gctcagcgtc
    34681 gcggtttctt cacgcatgtt ccagcggcct tccgatcatg gtcctgctca tcggcaccgg
    34741 catcctgctc gcccagccct ctgacggcct gcaacgcggc caatccctgt atcgtgaaca
    34801 ttgtatggat tgccacggca ccgcggggaa gggcgatggc cccaaggctc cgtttttatc
    34861 gccgcgcccg gggaatctcg tctctgcagc cacctctgca aagacagaca aggagctcct
    34921 ccggacgatt gctcaaggca aaccccgcac agccatgccc ggctggaagg aggcgctccc
    34981 ggaggaagat caacaagccg tgctccaata cattcgctcc ctgattcaat tttcccgttc
    35041 tcccaccgct actcccccga ctccctgaac acgtgttctt aagccaggcc tctttcgtct
    35101 gaaaagagcc gcgtgataga gtgaccttct tttatcctca tcggaggtcc ttcgtatgat
    35161 ccgcgggaac ctgtgccatc accgacagac cattgccatc cttgccctgg cgcttgcatt
    35221 cggctcctgg gctggaatcg ctgaatccgc gccggccgtg ggcggaaagg gacatgccaa
    35281 gaccggcacc cctaaaacca caccggcgat acaaacagcc atacggtatg ctgaagcact
    35341 ttcgcagggc gatcgcgtga cagccggcca attggacttt gcctgccagt atcggcacct
    35401 caccgcttcg ccgacgaagg tgaaacaatt cgcgccgaaa gatgatccgt cttacgacgc
    35461 gtgctggcag aacctgaccg acgcctatgc ccccatgctc accaggtcag acatagcgat
    35521 ggatatcatc tggccgagca cgggtccgct gctgttcttc ggcgatgacc tacccagagc
    35581 gcctgcctcc gcgtttgtgg cggatgccgt gggtgttgca cctccgggca gcggactgca
    35641 tgtgaccgcc ttgaacagcc gcacgatccc ctccgggtcc ttcaagctgg cgcgcaccgg
    35701 aaaagtcctg gccgctccga ccaccctggt ccaactgtcc gtgcagtatc aggatcccct
    35761 cacatcgccc gtcacctatg ctgccgggaa cgtgaagtgg acgaatacga tcaagcggcc
    35821 gcggcgagca ttgaaatccg tcaccctgca gtgggtcgtc ttcagcgggc tgaagcaaca
    35881 tggttttcct ggggatacgg cggtgttcaa cctgccggtt ccttcacagc cggaagcacc
    35941 cggcatgatg acagacaaaa ttcccttcac gacagaaacc agccgcgcgt tacctgaatc
    36001 catggcctgg tggggaccgg acgaccaacc gggtgtcctg accgcggcgg cggcacgggc
    36061 cgccatcttc ccagacctgc gcgaccgggt cgccttgctg aaccgtgtct tgatcatcga
    36121 tcccaaacag cccgatgctc ttacggtgct gacccgccat ctgtacagcg cgctgctgcg
    36181 ggaggcgaga agcagtcatc aagtgccggt caaggatccg gcgcttggca tcgtgctgga
    36241 tgagttttat tggaacattt acgcacaagg catgcgcctg gacctctcca acggcatgga
    36301 aatgggcggc ctctcgcaac ccacgccggc agattttctt tatcgcctca taccggctct
    36361 tcaaaccttg gccgagatca gaccggaaca actcgacaac cggtttcgct tgggagtcgc
    36421 ttatcggtgg aacaacgatc agattccgat ggtcgaaacc ttcgaagcgt tggtcaagga
    36481 tattccggag catcgcagaa cacccaaagc cgaagccctc ttgcaactgg cctggtctcg
    36541 tatcaacaag gtgtcctgga accggatttt gcatgacacg gaaactccgc gagcctatgc
    36601 caatgccgaa gcctcactgg catttgccga acttcccttg gataagttcc tcgcagaata
    36661 tgccatggcc tacaccatga tctttctgcc caactatggg gacaaggaga agatgctcca
    36721 tcacctcacc gaagccaaac gctggttcga tgaagtgccg gggaaaacga acgaggcctg
    36781 gcgctatttc ctccatacag gcctactgaa agcggtgctg gatgctgacc ccatttttgc
    36841 acctatcctc gcaacagtcc ctagccagcc gtaatcatgg tcactgatcg gatggcgaag
    36901 gccaaagcct tcgccatccg attggccgcg ccatcactct ctcgtcgcat ccgcccctcc
    36961 gtaccttgtc aagctggaca agctgtggta acgatgaccc gacagcattg aaggggagtc
    37021 gcagatggcg gaaacatcac atcctggaag cgtgcaaaga actgttggta tcgcctgcct
    37081 cacggtttgc tatctgaatc tgacggcctg ctctctcttt ggcggaactt ctcaatcact
    37141 gacggtgaat tcagatcccc cgggcgccaa tgtcttgatc aacggcacct cggccggcac
    37201 aaccccgctg cagtaccagg ttccacgccg cggagacctg acagtcgaag tacaaaagcc
    37261 cgggtacaca ccgcagaccc gagtaaccgg ccggaaactc agtagtgtcg gcatcgtcga
    37321 tgtcatcggt ggtgccttgt tcttgctgcc gctgctgggc ctcattgcgc cgggcgcctg
    37381 ggaacaagac ccgggcatca tcggcatcac actcgaaccg gatcaccctc aacccgcgca
    37441 gcctcaataa cttcggaccc acgattacgc tgtacgatca gaccgtaagg aacaggacta
    37501 tgattgacgt caaaggttat gccgcccgca ccgcaaaatc ccgactggct ccgtttacgt
    37561 tctcacgaag aaacgtggga aggcaggacg tgcttatcgg catccgctac tgcggcattt
    37621 gtcattcgga cgtgcatcag gcacgggatg aatggggcgg ctcgatcttc cccatggtac
    37681 ctggacatga aatcgtgggc gttgtcgaac aggtcggcgc ctccgtgaaa caattcaagg
    37741 tgggtcaaat ggttggcgtg ggatgcttcg tcgattcctg ccgaacctgc ccgcaatgca
    37801 aaaaaggcga agaacagtac tgcgaaggcc acatcagctt tacctacaat gggaaggagc
    37861 gggacggcgt cacgccgacc tatggcggct actccaccaa agtggtggtc gatcagcgct
    37921 acgtgcttcg catccctaag caattgcgtc ccgaggaagc cgccccgctt ctctgcgccg
    37981 gcatcacgac ctactcgccg ttacaccatt ggggagtggg aaaggggcac cgcctggcga
    38041 ttgtcgggct gggagggctg gggcacatgg cggtcaaaat cggaaaagcc ttgggcgctc
    38101 acgtgaccgt gctgagtcat tccgacaaaa agcggcgcga tgccaaacga ttgggcgcca
    38161 aagattttta caagacctct gaccccaaaa ccttcaccac cctcgccaaa caattcgact
    38221 tcattctgga caccgtatcg gcgccccatg acctggatgc acagctggaa ttgctcaaaa
    38281 ccgacggcac catgattctc gtcggggtgc cggacaaacc ggcgcaactg ggggcttttc
    38341 cgttgatcct caaacggcgg aggctggtgg gctcattgat cggcggcatt caggaaacac
    38401 aggagatgct ggatttctgc gcgaagcaca aatgcggcgc cgacgtggaa gtcatcccga
    38461 ttcagaaggt gaatgaagcc tacgatcgcc tcgttcgcgg ggacgtgcgg taccgcttcg
    38521 tcatcgacat gggttccctc acctaacgca ccacgtcttc ttcgttgcac gcgacatcca
    38581 tcgtccgatg tcgcctcggc atgcccagct atcagcagca cggagccggt acacgtcaac
    38641 agtctcaatg tgttgaatgt gagtctaccg aggagagagg caggccgggc ggctgtagcc
    38701 gcccggcctt tcctcaaaga cacaggaact tacttggcag gctcaaccaa cggcatcaaa
    38761 ggaagctgtt tcgcgtcctt gtccaccttc agcagtgcga tcgcgccccg aagggcatcc
    38821 gtcaaagagt gcgtgacgat gggatacaca ccgtcattgc cgtccaacac catatcgaga
    38881 atggccgctc ccgccggcgg gatgagttgc gtttgtactc cgcgcgtatg gttggcgggg
    38941 ttgccgcttt cccagacatc atcccagatt tcggcaatcg gatggaccgc ggacacattg
    39001 ttcggtccgg cattgacgaa atagaaccgg acgcgctcac ccggcttggc ttctaaaaag
    39061 gcgcctcccg ccttgctatg cacggggtca taccggaaca ccgccccgtt aaaaacgacg
    39121 tgctgatatt tccggtcgaa catgccgtcg acatcgtcag gatctttgaa cagctcgctc
    39181 tgcaccaaca catattctcg atccgccttc ggcatcgcct tgggatcctt gggatcgacg
    39241 atgatggcgc ccatcatccc gcgcgcgatg tgctggatca tgggagacgc gccacagtga
    39301 taggcaaaca cgcccggcca tttggccttg aaccgatatt gcaaagattc acccggccgc
    39361 acttccttgt agtgctccag gaaattggtt tcggcggcgt gaaaatccat ggagtgaggc
    39421 cggccgttgg tctccggatt cgtgagcgag aaaacaactt catcgccttc ctgcacccga
    39481 atcaccgggc ccgggaactg cccgttgaat gtccaggcat catatgtatg tccctcgccg
    39541 tcgataacga gcttggtttc cacggccgtc atggacactt cgacgacttt cgcgaacgcg
    39601 gattcgaccg gttgcatggc gaggcctgac attgccgcca accctaaaac cgtgcggatc
    39661 acagattgac gaaagcggat attgcgtact gtcataatgc tgcggctcct cctgtgaaag
    39721 tgattggtct cggttcaccc agaaccgtgg tgaggatacc gcgcaacgcg acaaatcaag
    39781 tatgacattt gtcatgtttt aaaaatgtcg cgccggctgc cgccgatcgc ctatcgggat
    39841 cttcggccag ggcattaccg cttggcagct aaatccgaaa aataatgggc gaaggccttg
    39901 atgccgccgg aggcctgccc ccaatcgaag tactcattcg gcgcatgata tccatgctcg
    39961 gggaggctga gacccataaa caggatcggc actttccacg ccttttgcat cgtcaccacc
    40021 gcaccgatcg aaccgccttc acggatgaag gccggctcct tgccgaatcc ggccaggacg
    40081 gcacgcttaa ccgcttcgac atagggaccg tcgaacaccc cacggaacgg atgcaacata
    40141 ccctctcgct ccaccttcac cgcgggattc agtttcgcca cgtagtgctt caacagggca
    40201 aagatcttct caggcgtttg accggggacc agtcgcatgc tgattttcag ttcgccatgg
    40261 ccgggcacga tagtcttcac gccggggcca tgataaccac ccgtaaggcc atgcacttcg
    40321 aatgtcgggg cggcccaaat tctccgcatg acctccgccg ggtcgtgcgt gcgcaaggtc
    40381 ttgaacccgt acgcttgctt gaacttgctg acctggaaac ccgatttcaa gaaactcgcg
    40441 atctccgcct tcgttggcgg cacgacctcg tcgtagaatc cggggatttt caccttaccg
    40501 gtcttggcat cgacacaggc atgggcaatc tccatcaact cgacgagcgg attccgggcc
    40561 gccccgccgg tcacgccgga gtgcgcatcc ttggttccgg ttcgaagggt cagccgtgcg
    40621 ccgagtaatc ctcgcaatcc atacggcatc gccggttgat tcttggagag ccagatggtg
    40681 tccgaaatga ccaccgaatc cggagccgga atcgccgccc ggttcttgat cgcggaggca
    40741 aaactgggac tgccgttttc ttcttccagt tcccagagaa accgcacatt gatcgggacc
    40801 ccttgatcaa tcgcatatcg cgcgccgaac agggccgcga gggccggccc cttgtcatct
    40861 gtcgcccctc gcccacggta gatgccgtga tcattctgga aggcgaaggg agcctgcttc
    40921 cattccggtt cctgcgccgg ctgcacgtcc atatgattgt agaccgtcac ggtaggatag
    40981 tgaggatcga ccgtccagcc gcctgagacg accgggtacc cgggcgtttc cacgatctgc
    41041 gcttccgcac cagccgcccg cagatactgt gtcgccagtt cggccatgcg ccgcacatcc
    41101 ggcgcatggc gggggtccat gctgatggac ggaatctcga ccgcctgccc gagcatgtct
    41161 tcatactgcg gacggatatc ctttatgtat gtctctatct gccgttgcac gtcgctcatt
    41221 gatgctcctc cccgatctca gtggcagtgc ccgaattccc tcacatcatt tctctgcatc
    41281 acactcacta cgtaggaccc aatcccagtc acggcgatta tatccagtcg gaacaggaaa
    41341 gcctatgttg gcgacgatgg cgagaaagca tgtagaatga aaccgatgca cgataacact
    41401 tctcaccaag cacttcgtat gggcacagca ctgttggctt gcctggcatt gtgtctttca
    41461 ggcggcaaca gagtattcgc gcaagaagcc gtgaccgtgc aggaagtgct cgctgatccc
    41521 gcgctatttc atttgcgaca aatcaccatc aagggcaccg tgcgtcaggt ccaaccgctc
    41581 gatccctacg agatcccggc cggctcaacc tgttacggcg gctatctgtt cagcctggaa
    41641 gacgacacgg ccaccctgtc catcgccgta cccggactat gcggcgtgcc gatggtgaaa
    41701 gatccggacg tggaagacgg tgcccgcgtc gtggtcgagg ccacggtcca agctcccagc
    41761 catggagggt atgccttgag cttcaaaggc gccaaaatcg ccatggatca agaaggcgtt
    41821 gtacaagcca ttgcaaaccg gatcacgcca ttggtggaat aaacgatgac gactcgtcca
    41881 cttgaacaga ctgcccgcgt cgcggccccc gcccatacgc gcgtcggctg gattggcacc
    41941 ggcgtgatgg gcgcctccat gtgccgtcac ctccaggctg cccactatcg ccttacgctg
    42001 tttacacgca accgcggcaa agcctcagcg attctcgcca aaggagcaac ctgggccgat
    42061 tctcctcgcg cggtggccga gcagaccgat atcctcatca ccatggtggg atttcctcgg
    42121 gatgtgcgcc aggtgtactt cggggaccat ggtgttctgg ccggcgccgg cgcgggcatg
    42181 gtgctggtcg atatgaccac caccgaaccc tcactcgcac aggagattgc acaggcggcc
    42241 caatcgcgcg gagtgtttgc cgtcgatgcg ccggtctccg gaggggatat tggggcgcgc
    42301 gacgcaacgt tatcgatcat ggtcggtggt gaagccagcg ccgttcaaac gatcatgccg
    42361 ctgctcgaat gtctgggcaa aaagatcgtt caccaaggcc attcgggagc cggtcaacac
    42421 acgaagctct gcaatcagat tgtgatcgcc ggcacgatga tcggcgtctg tgaaagcctg
    42481 ctgtacggct ataaggccgg actcgaattg ccgcgcatgc tggaatcgat ccgcggcggc
    42541 gccgctgcct gctggacgct ggacaatttg acgccccgca ttctggctcg caacttcgac
    42601 cccggcttct tcgtcgaaca cttcatcaaa gacatgggca tcgctctcga ggaagcacgg
    42661 cgccggcagc tcacccttcc aggactcacg ctcgcacatc aactgtacga gaaggtggag
    42721 gcgctgggcc atggccgctc cggaacgcac gcattgatgc tggcgctgga agccctttca
    42781 aacatcgatc caaccagacc ctcgacctca ctctaatcac aggagccgca tgagaacggg
    42841 tacgcatcct cttgttctgg cacttatcct caccatcacc tgcaccgcct gcaccggaac
    42901 ccgtggcctg aaccggcaca tcttgcagga atcctttcat gatcatccgg acgtaacgac
    42961 tgatcgcgcc atcgccgcca ccatggcaac ccaggcaaca ttgccgacgc cgtatcgcct
    43021 cgccatttat ttcaaacatg aggatttccc cagccgtccc gccttgcaac gagtggactg
    43081 ggtcagttcc gacggcgccc gcgtgcaacg gtcactggaa ccggtgcagg aagaaggcat
    43141 tcttcaacga accttcttgc tcgccaattc aaccgtgcag ggcaataccc ttcgtgacat
    43201 acggctcgcc gcggcccgct acaacgccga tgcgattctc atcatcgacg gggcctcggc
    43261 ttttgaacgg tacaacaacg gccacgcctg gtggtatgcc accggcatcg gcgcctactt
    43321 tgcccacggc actgaatgcc atgccctgtt catgatggaa ggcacgttgt gggatgtccg
    43381 gacaggctat ctctacggca cgcaaacggc ggaaggagaa acaacgctca tcggtcccgc
    43441 cccctcactc gacgacaaag ccgcggtggc cgaagcgaag gatgtggcga tggcccgctt
    43501 cggcagagaa ctcgccgata cattgcggct gctgaaggaa aagcagaagg caataccgtg
    43561 aacgccctcc tcagtttctg cttccagttg tgactgagat gctgcctgcg tatggtcgcg
    43621 aagcagttga gaccgaaatc cgccgcggtt gatccgaacc agcaacagct cgcaactaca
    43681 cctcggtctc ctgggcgctc aaaatggctt tcgtgcgagg ccgcaggacg cgagggactg
    43741 aggcgtactc tctgcagtac gtcgaggtca cgagtgcgcc gagaacgaag cccgaagcca
    43801 ttttcagcgc ccgctcacgg actatcgaac gtccatagaa ttccgagcaa caccaggtgc
    43861 tgattcggtg tgagactcag cacgccgggt tgcacctctc cacgccgaaa gaatccgcct
    43921 cctgctccgg tcgattcgtc ccatcgatgt tcgaggcgca ggatggtatt cgtccatttg
    43981 tagggaatct tgtattccac ggtcgacgtc accgctttca cgaattgctc cgatcccgtc
    44041 caccgcccgt ttcggtccca gtagaactcc ggcctcgcca ccagagtcca ggggccggcg
    44101 acatgccacc gggctaccat atttccgccg gtcacaaagg cccgcggatg gccgggacga
    44161 tcggcgatgt tctcggtccc gatgtcgtag gacagtgcca gcgtgagatc gtcgcctttc
    44221 cattccacga tatggttcgc gtaaaaccgc cagaactgca gcgcggtatt gctttgatcc
    44281 ggcccaccat agagagtttg cgtgagcgtc agccgaggtg tggccttgta ggcccattga
    44341 ccgccataac tgggctgatc gttgggatgc gagagatggt aatagccgtt gatcacaaac
    44401 gcggtgatgg tcaactcatc gctgacggga tatttggcat tgacgccgaa catcatgtag
    44461 ggcgtattgt ccgcaatcca ggaacgcgtg tagttcgcat tgtctttcgc atacaacgac
    44521 tcatagccga taagactgtt gaataacccg gcggtgatgg taagcccctt gccgatcggt
    44581 gccagatagg acacattcgc gcgatggatg tgccgcaagg tatcggcccc gctgacttcc
    44641 cgttccccct gcaaaaatgc aaagcgctca gagtcgtacc ctccttgcac gccgagttcc
    44701 atgccccacc gtgaagattc attcacatct ttgcgaacat aggcgagggc catgttcggc
    44761 gcgaactcat tatgccgcgc cgccgtggcg cggtttcgcc agagatggtt ttccggaaaa
    44821 ttgaaattca gaatgtaggc aacatcgaga tacgcgccgt agtgccagag cccgctatcg
    44881 gcgctgacag ccggactatc accgggcgtc gaacttggtt cggcggcata cgccggggcg
    44941 atcaacaacc aaaagaacag cacccacccg agccgactca tcccggccga aaagataggc
    45001 ctcacagcca gaccgatgtc gttgcgcaac ggcagaatag gttccatctc atgctcatga
    45061 tccaacaaac ttcgcgccct ccggaaatcg actctacggc atttcgtatc aaaacagcat
    45121 taaaaccgat catggagatg taagagatcc gtaaaaacgg ccggaatact cattccgccc
    45181 ggagtcgata gccgaccccc agttccgtca cgagatgacg aggctgagcg gggtcggcct
    45241 cgatcttatt cctcaattga cgcatataca cacgcacata gtgtccttcg tctacatgga
    45301 ggggccccca cacttctttg agcaactggc gatgtgtcac gaccttcccg gcataccgca
    45361 cgagcgtcgt gagcaactta tattcaatcg gcgtgaggtg gacttccgtc cctgagacaa
    45421 acacttgcct tcgcccgaga tcgacggtca cctcgccgaa cgtacatacc ggctcaaccg
    45481 cgtcaccgat cgggcgatgg gcatgccgca acgccgcgcg catacgggcc agcaattcat
    45541 ccacgccaaa cggtttcgtg acgtaatcat cggcgccaag atcgaaggcc tgcaccttga
    45601 cctgttcctg gtctcgtgcg gagagcacga tgatcggcat gttcgaccag gcacgaattt
    45661 tctcgatcac tgcggtgccg ttcatgtcgg gaagaccgag atcgaggaga atgatgtcag
    45721 gatttcgagc ggagatttgc gccaacccat ccgcaccggt ggtcgcttcg tacaatcggt
    45781 aaccataagg cgggagagtc gtgcgaagaa atcgtcgaat ttctgcttca tcctcgatga
    45841 gcaggacggt tacctcatgg gtcgtcgtgg atggcatgga tgacagatct taaatggccg
    45901 cgctgtcgtg ctggttcgct tctggctcga cggtcggctg acttttttct gccggcagcg
    45961 taaagcggaa actcgatccg ccaccggaac gagagtctac ccaaatacgc cccccgtggg
    46021 attcgatgat gccccggcag atcgtcaatc ccagtccgac gcctccctca cgctcaggat
    46081 gaagctgata gaacttttcg aagatccgcc gctcttcgcc ttgaggaatt ccgggacctc
    46141 gatcagcaat ttctatcaga atcaccccgt ccttcaccga cgccgtcacc tcaatcggag
    46201 aggccgtcgg agaatatttc gccgcattct ccaacagatt aatcagcacc tgttcgatca
    46261 acaccccatc gacgagcacc aggggaagat tgaccggaaa ggcggtcgtg accgtatgcg
    46321 tggcgatccg ggatttcacc cgggccaatg ccgtgcccac cagctcctcc agcgcatgcc
    46381 attccttgcg cagatgcatg gctccagctt ccaatctcgt catatcgaga agattcttca
    46441 gcaaccggtc gagtcgtccg gcttcatcgc taatggaacg gaccaggtcc tgctgactct
    46501 cggtcgatag gggccgggtc gtgctcagta aggcactgct cgcgcccacg atcgtcgcca
    46561 gtggcgtccg aaggtcatga gaaacagaac tcaggacggc attgcgcatg cgctccgttt
    46621 ccgtctgcac gtgagcttct tgagcttctt cggctaatcg cgcacgttcc agcgccaacg
    46681 ccatctgatt tgcgaaggtc tccaggagat gcagttgttc cggagcgagc agttcggcag
    46741 gtcgagacga tcggaccgca aggactccca cggccccatg agaccccaac aacggcagat
    46801 acagcgaatc agatccggac agggtattgg tgccgtgacc ggcggattct ttatggtcga
    46861 acacccattg cgagatgccg gcttccttcg gatccagctc gaaatgcagc gcttcacccc
    46921 gatgaagatg cacccgccct tcccgatcag gaaggaacac ggccacctga caatgaaaga
    46981 cgtcgtggat atggcgggac gccactgaag ccagtttgtc caccccacgt tgagtgatca
    47041 attccctgct catggcatag agtgcggcgg ttcgcttctc acgaatcaag gccgcctcgg
    47101 cctgctggct cttgtgggca gcgagtcggc tgatcagcag cgctactaga agcatgactg
    47161 caaatgtcag cagatactgc gcgtccgata cggcgaatga atagtagggc gggatgaaaa
    47221 agaaatcgaa ggccgcgacg ctcatcagtg aagccagcgc tgaggggcct cggccccatc
    47281 tggtggcaac gaccaccacc ccaaacagat acaccataat gagattagcc tgcccgaagt
    47341 atggggacat gaccagactc aatgccgtgc aggctcccac aaccgcggag gcgtagccgt
    47401 agttccggcg ctcactggtc cgttgaagca atcctttcac aagaggtttg ccagtacccc
    47461 cctcaccggt catcacatag atatcgatgt cgccgctccc gcgaacgaga tcatccacaa
    47521 ccgaaccgaa cagccattcc ttccagcgcg aacgcaatgg ttttccgaca ataatcttgg
    47581 tggcattgcg gcttctggca tacgccagta actgcgcact cacgtcctcc cccgtcaacg
    47641 tcaccgtttc tgcgcccatc cgctcggcca accgcaaggt gtcgacacct tgattccgct
    47701 cctgatcaga caaccgcaga tgctttgagg tctggacgta gacagcgatc cacctggcat
    47761 ggaggcccgt ggccatcttc ctggccgcgc gaaccagcat cggcccacgg ggtttcagat
    47821 tcacgcaaac caagatggtt tccgctgccg gccaggtgcc aacgaccgca tggtcccgac
    47881 gatacacttc catttgttga tcgacacgct cggccgtccg acgcaaggcc atctcccgca
    47941 acgcgatcaa attacccttc cgaaaaaaat gcttgatggc gtgctgtgcc tgatccggca
    48001 gatagacctt gccgtccttg agccgttgga ggagatcgtc cggagggaga tctaccaatt
    48061 cgacgtcgtc agcctgctca agaacggcat ccggcacggt ttcactcaca cgaatgccgg
    48121 tgatttgagc tactgcgtcg ttgaggcttt cgatgtgctg gacgttcacg gtggtataga
    48181 cgtgaacgcc tgcttgaagg agttccctca catcctgcca ccgcttggga tgtctggaac
    48241 cgggggcatt cgtatgcgcc agttcgtcca ttaagaggag ctgcggccgg cgcgccagag
    48301 cggcgtcgag atcgaaatcc cgaagccttg atcccccgta gaccacctcc cggggaggca
    48361 gagtcggcat cccatggacg agcgcttccg tttcggcccg gccatgagtc tcaacccacc
    48421 cgatcaccac atcgatgccg tcccgttgct gctcatgggc tgcctgcagc atggcgtagg
    48481 ttttcccgac ccctgctgtc gcgccgaaaa agaccttcag tctgccgcgc gtctgatcgg
    48541 cttcttcagc ctgcacgcgc ctcagcagta gatcgggatc cggacgctgg ttctccatgg
    48601 cactcctgga caaagaaatt cgatggggga cgaaaaggcc acaagattgg cagagcaaat
    48661 tctagaagac agacggaaag gcgtcaacga gcctggccgg atgcatccaa tgcgaggttc
    48721 aacgccagca cattgacccg gcgttcaccg agcagtccca gctgacgccc ttccgtatgt
    48781 tggatgacca gtgtcctcac gactgcttcg tcttttcctc gtgcacgagc gacccggcgc
    48841 atttggtact ccgccgcggc ggggctgata tgcgggtcaa ggccgcttcc cgacgcggtc
    48901 accagatcga ccgggaccgg tgcatcattg cgggggtccg cagccttcaa cgcagccacc
    48961 ctcgtcttga ccgcctccgt cagcgcggga ttggtagggc ccagattcga accggaggag
    49021 gcggaggcat tataggggaa cggagcggtc gcggaagggc gtccccagaa atacttggga
    49081 tcgtcgaagg gttggccgat cagcgtggac ccgatcggct tgccgtcttt atagatcaga
    49141 ctgccattgg cctgatgggg gaacagcagc tgcgcgatcc ctgtcacggc cagcggatag
    49201 gccacaccgg tcagaatcgt caggatgaaa aacaccatca gcgcggatcg aagttgagcg
    49261 gccatcgtga tctcctcaga ccagtcccag ggcgaccagg agcaggtcta tcagtttgat
    49321 tccaatgaac ggaacaatga tgccccccag tccgtacacc agcacattgt ggcgcagcag
    49381 caaggaggcc tcaatcggcc ggaacttgac ccctcgcagc gcgagcggaa tcagcgcgat
    49441 gatgattaag gcattgaaaa tcaccgccga caagacggcg ctttccggcg ttgccagtcc
    49501 catgacattc agcgcgccca gggccggata cgtcgtggca aacgcggcgg gaataatcgc
    49561 aaaatacttc gcgacatcgt tggcgatact gaaggtcgta agggcccccc gcgtcatgag
    49621 gagctgcttg ccgatttcca cgatctcgat caatttggta gggttggaat ccagatcgac
    49681 aaggttcccc gcttctttgg cggcctgggt gccggtattc atggcgacgg ccacatcggc
    49741 ctgcgccagg gccggcgcgt cattggtgcc gtcgcccgtc atggccacga gtcggcctcc
    49801 tgcctgaaga tcacggatga gtttcaattt ggcttcggga gtggcctgcg cgagaaaatc
    49861 atccacgccg gcctctgcgg cgattgcggc cgccgttttc tggttgtcgc cggtgatcat
    49921 catcgttttg atgcccatgc ggcgcaactc ggcaaaccgt tccttgatgc ctcccttgac
    49981 cacgtccttc aaatgaatca cgcccagcac tgttttgcct tcggccacga cgagaggagt
    50041 gcccccttgc atggcaatcg tctcgactgc atcgcgcacg gcgggaggaa acgagccgcc
    50101 ttgttgggtc acgtagtctt cgatggcctc cgccgcgccc ttcctaattt gtcggtcgtc
    50161 cagatcgacg ccgctcattt tcgtttgcgc cgtgaacggg aggaaggtgg cgcccatcgc
    50221 atggatatcg cgccctctga taccatagcg ttcctttgcc agaatcacga tgctgcggcc
    50281 ttcgggcgtc tcatcggcta gcgaggccag ctgcgccgca tcggccacag acgtttccgg
    50341 cacgccttcg gctggaataa atgccgtggc ctgccggttg cccagcgtga tcgttcccgt
    50401 cttgtcgagg agtaacacgt ccacatcgcc cgccgcttcg acggctttcc ccgacatggc
    50461 gatgacgttc gcctggacca tgcggtccat gcccgcgatg ccaatggcgg ataagagagc
    50521 gccgatcgtc gtcggtatga gacaaaccag cagggccacc agcaccgtga ccgtaatcgg
    50581 cgccccctgc cccgtagcat gcacggaata gagagaaaac ggcagcaagg tcaccgtcgc
    50641 cagcagaaag acgacggtga gggccgccaa gagaatattg agcgcgattt cattcggcgt
    50701 cttctggcgc ctggcaccct cgaccatggc gatcatacga tcgagaaatg tttcaccggc
    50761 gctggtggta attcgcacga caagccaatc tgacagcacc cgcgtgccgc cggtcacggc
    50821 actccggtca ccggactccc tgatcaccgg cgcgctctcg ccggtgatcg cactttcatt
    50881 gacggatgcg atcccctcga tcacatctcc atcgctggga atgtaatccc ccgcctcgac
    50941 cagcacgatg tcacctttct tcagcagact ggctggaacg agactgtaga cctctcccgg
    51001 tttgccgatg gcggcaggcg ccgccaggta gtctcccccg gaggcaggtg ttccaaatcg
    51061 cttggcggtc aactccgtcc tcgatttgcg gagcgaatcg gcttgggcct ttcctcttcc
    51121 ttcagcaatc gcttctgaaa aattggcgaa cagcacggtg aaccagagcc acagcgagat
    51181 ggcgaggata aaccaggtcg gtgcttcgcc cgccccgaac aacgcctgga agaacagcag
    51241 cgacgtcaag aggcttccca cgaagaccac gaacatgacc ggattgcgga cctgaatgcg
    51301 aggatggagc tttcgtagcg catccagcag ggcctgtcga acaagcggcg gatcgaagag
    51361 cggtctggct ttcgtcgatg tcgtcatgga aatccctctg ctcgttcagg ctagcgagcg
    51421 accatcagca aatgttccac caccggcccc aacgccaggg ccggaacgaa ggtcagggcg
    51481 ccgaccatga tgacgacccc tatcagcaag accacgaaga gcggcgtatg agtcgggagc
    51541 gtgcccaacc ccggcggcac catctttttg cgcgccaacg atccggcgag cgccaatgtc
    51601 ggaatcgcca accagaatct ggagaccagc atggccaatg cgcccgtcac gttgtagaag
    51661 ggggtattgg cattcagtcc cccgaaggca ctcccgttgt tattgccctg ggaggtatag
    51721 gcatacagaa tttcactgaa cccatgtgcg ccggcattga gaatggacaa cgtgccggac
    51781 tcagtcacga ccgccactgc cgtgaacccc aggacaacga tcggcatgat gaggatcaac
    51841 agcgcggcca tcttcatttc ataggcctcg atctttttcc ccaggtactc cggggtccgt
    51901 cctaccatca gaccggcgat gaacaccgcg ataatggcga aaaccagcat tccgtagagg
    51961 ccggacccta ccccgcccag aatgacctcg ccgaattgca tcatgagcag cgggatcaaa
    52021 ccgccgagtg gcgtaaagga atcgtgcatg gaattcaccg ccccggtgga cgtggctgtc
    52081 gttacggtgg caaaaagcgc cgaacgagca actccgaagc gagtttcctt gccttccatg
    52141 ttgccaccgg actgcgctat ctggacgttc tgctcgacac ccaacgcagt caggcgaggg
    52201 tttcctgcgg actccgccca gtaggccccc agcacgaaga aggccaatac gctcagcatc
    52261 gcagcgagga tggtccatcc ctgcctagtg tcgccgacca tcattccaaa cgtataggtc
    52321 aacgatgcgg cgatcagggt ttcagccagg atcagaatga aatcggtgag cggcgtcggg
    52381 ctttcatagg gatgggccgc attggcatta aagaatccgc caccgttggt ccccagatgt
    52441 ttgatagcca cttgggacgc tgccggaccg acggccaaga cttgctcaat cccggttgtt
    52501 gattccattt tggcaacgcc cttctcgtcc actaccggct gacctgcggc atcgacgacg
    52561 ggcttgtcat aggtcacagg ctggaggaga gcggtttggt gatacaaccc gaaggtctgg
    52621 accgtccctt gcgagacgag aaccagcgcg agaacggctg acagcggcag caagatgtac
    52681 aacgtgctgc gagtcaggtc cacccagaaa ttgccgatgg tcgaggccgt ccgagcggtt
    52741 aacccgcgga tgagcgcgac cagcacggcc atgcccgtgc cggcggagac gaaattctga
    52801 actgtcaggc cgagcatttg cgtgagataa ctgagtgtcg attcaccggc ataggcctgc
    52861 cagttcgtat tggtaatgaa gctgacggca gtattgaatg cgaggtctgg cgccaccgcc
    52921 ccgaaagccg acggattgag cggcagcaat ccctgcagtc gctgcaaggc atagagtgcg
    52981 accaatccgg cgacattgaa caacaacatg gccaccgcat agctcgtcca gttcatggcc
    53041 tcggcttcgc gcacgccaca gacacggtag atcaggcgtt cgaagggtcc catcacccga
    53101 tccattccgc aggcctggcc cgtgtagaca cgcgccatat accagcccag cggtttaacc
    53161 aacgccgcca aaacgagaaa gaacagtccg atttgagcca acccgttgat cgtcattaga
    53221 accactccgc tttcagcagc gcgaccatga ggtacaccaa caaacccagc gacaacactg
    53281 cgccgaggac atacatcgca ttcatgacca gacccccttt agagtcggtc caacgccgag
    53341 ataagccagc cggacagcag aaaaaacaca gcagcgatcg ctaaatagat gagatccatg
    53401 tcaatgttcc ttaatgagac ggcacacgta ttgaggcgcg cttcgccgga gtctctttcc
    53461 aagccgtcgc caaccagcca catcgctgca cgccccttct cttccaccac atgttcaagg
    53521 tagcgcgcag aaagtaaaaa cggtgtaaaa aagcgaagga aatggatttc tgagaagatc
    53581 ttccccaaca gctgttcacg ggttcggagg agatcgctac agacgactga tcactcgtaa
    53641 tacatccact tacgagcggg gtgctaagga agacatgtgg acaaagccgt gaccgtctat
    53701 tgatcaggtc acagagaatt gttggagcaa ctagagaggc gtgactgcat caggacacta
    53761 ctgatctgaa tccgggcaat ctttacgtag ctcagccaac accgccagaa tttcgaccgg
    53821 ccgtggagga caaccggcaa tacggacatc gaccggaatg tggcgatcta ccggacccgt
    53881 caccgcataa ctccccttga acattccgca agtgatcgcg caatcaccca gcgcaatgac
    53941 gagcttcgga tcgggcgtct gcttatacac atcctttaag gcgcgctcca tgttgacggt
    54001 caccggccct gtcaccacca gcgcatcagc gtgtcgcggc gacgcagcga tctccacccc
    54061 gaagcgctcc acgtcataga cgggattggc cagcgcattc atttccatct cacaggcgtt
    54121 gcacgacccg gtatccacct ctcgaatcgt gagggatcgc ctgaatggct tgaccttttc
    54181 aatcgcctcc cggctcaccg gctcttgtga cgccttcgcc ataggatatt ggcccgtgac
    54241 gacgccagtc gtaagacttt tcttaatgat tcgaaacatg gcacctccgt gagatcgtcg
    54301 ggacaatcgc gcagtcagtc gccttcagct tcccgctaca gatcattgcc ggcataggac
    54361 aaattgaagc tcttattgat caacggaaaa tccggcacga tgttccccag cgccgcccac
    54421 tgaattgccg gccaatgcac aaacgatgga tcccgcactt tacaccggtg aatccgtccc
    54481 tcttcccctg ccatcacgac atacagaatt tcaccacgcc acccttcgac ggcagatatc
    54541 gcccattgcc cctgcgtcac aggctcgacc gcctgggtgg ccagcggccc catcggcagt
    54601 tgtcggcgaa gcgtatggat gagacgcatc gaatcatgca cctcatccaa ccgcacccgc
    54661 atgcgcgcgc ggacatcccc gtagcgatac accgcgacct tcggttgaca ctcgggatac
    54721 gcggcgaacg gccgatcccg acgcaaatcc cgatcgatac cggaagcgcg gcccacgact
    54781 cccatgaccg catgatccca cgcgatactt tccgacaaca ctcccgtgtt ctccaatcgt
    54841 tccgtcagag aggcattcgc cagcagaatc ttttcaattc cggaaaactc ctgttcaatg
    54901 gcttgcaatt ctgcgtcgac ctgcgacagt tgcacaccgg aaagatctat cgacactcct
    54961 ccgaccctgt tcacccctcg aagaaagcgt gacccggtca ggccatcatt caactgcatg
    55021 agctgttcct tcagacggcc acagtgcgca tgtgccagcg cataggccgt atcgttgcag
    55081 atggcgccga catcgccgat gtggttgtgc aaccgttcca gctccagaaa gagactccgc
    55141 agatagcggg ctcgtggcgg caccgtcatt cccaagagtg tttccaccgc ctgacagtag
    55201 gcgaggctat ggccgaccga ggtatcgccg gagacgcgct ccgcaagtgg cacagcctcc
    55261 gtgaggcgct gttgctcgaa tagtttttcc accccgcggt gcttccagaa atgacgcact
    55321 tcgagctgga ggatcggttc cccggctacc gaaaaccgga aatgacccgg ttcaataatg
    55381 cctgcgtgga tgggaccgac aggaatttcg aagacgccat cgccgtggat tttcctgaag
    55441 gcgtattccc cctgcgcacg ctccagcacc tgatcccagg caaattcttt cttcagcgga
    55501 tgcattccct tcggccaatg ttcatgacgc accagcctcc gcatgtccgg atggcccacg
    55561 ggaatcaagc cgaagagatc acggatctcc cgttcatacc acttcgccgc atggaccatc
    55621 ggggtgatcg acgcaaactc ccgctcctct tctgcgagat caaccgtcag gagcaaccag
    55681 tctttgcgtg ctgccagcgt gaataggtac cagagttcat cgcgagcttc gcgagggcga
    55741 tgatcgatgg cccagaggag cgaaagcgag ccgcgcaatt ccggatcggt atggatatag
    55801 cgtgcgacgg cgggtacgtc tggcttccgg agacgaagca tgggcacgcc ctgcatcgaa
    55861 ccgacttgga tgatgccctg cggaaaggcc tcctgcactc gcgcggctgc tgtcagtccg
    55921 tccggcatag ggttcacctc accacaatga cgtggacagc tctagtcacc aatgtccgca
    55981 acgattcggg aagcatgacg ctcaagccga gcaacgccac gatcatggcc aacatcggta
    56041 catggccgac tgtccagggc tctcctcggc ggatctcgtc ctgcggagtg ccccagacca
    56101 tcgcgccaat gcgcgccatc atgccaccga acaggaccac gccgaaaaac aaaaagacgc
    56161 cgacgagtcc aagactccgc atttcatcgg aaaccgtcac cgccacgaac cgaccgacat
    56221 gcatcgtatc ggatgcaaaa ttctgtgccg agagcgccga taccacgagc aattcactca
    56281 cgaatggcga aaacggcggc aggccgacca acgcgaaccc ggctacaaga gtcgccagtg
    56341 ccgtgatcgg ttgcgatcgc ccaagccctc gtacatggtc gatctccaac gagtcgtacc
    56401 gccgatggat gttgcccgcg acaaaaaatg ccagcgcctt ggctaacgca tgattgagca
    56461 aatggaacag gcctccgaag gtaccgacca acccgcctac tccaaaaccg agcatggcca
    56521 gccccatgtg ctcgatgctc gaataggcaa acagccgctt ataattgtgc tgtaggagaa
    56581 tgaacagcga ggccaccaca aacgacacga acccgaacgt gagcagcaga ttaccggtga
    56641 actgaggcgg gagtgcctga tcgacgagcg ccttgctgcg cagcaccgta tacaccgcta
    56701 ccgtttccaa caccccggcc aacatcgccg caaccggcgc cggcgcttcc gtataggcgt
    56761 cgggcaacca ggtatgcatg ggcaccaagc cgaccttcgt cccgtacccc acgagaatga
    56821 agagaaacgc cagcttcagg acattcggat ccaatcgatc cgccaccccg atcagggctg
    56881 tcacgttcaa cgccgaactg gcatcgccaa gcacccgcac cgaggagtaa taggtcagca
    56941 cgaccccgaa cagggcaagg gcgatcccca ctgagcagag aatcaaatat ttccagccgg
    57001 cttcgagtga ttcccggcgt cgaaaaaagg cgatcagaaa ggtcgtcgcc aatgtggtcc
    57061 cctccacggc gacccactgc acgcctaagc tgttggccat cgtcgcggca accatggcga
    57121 acagaaacat gtgaaacagg aagaagaaaa cccccaggtg cttcggcgcg atcacagcac
    57181 gagcgacctg ctcatccata tacgaccaca tgtacagcga acaggagagt ccgatggccg
    57241 tgatgatgat gagaataaag tccgacaacg catcgatata cacgagcgag cccaacgtcg
    57301 taaccgatcc ttccgccaac acccgtttgg tcaggaaggt ctcggcgacg gctaatccca
    57361 gcatggtcgt aaaattgacg gcgtgcagca gccgcgcacg ttggatcacc aggctcagca
    57421 gcccggccaa gaccggccct gccaacaaca cgatcaccgg ccacatggga cacctgttcg
    57481 cgcgttctcc atcatcggat catcattcct tcaagaccgt taactcgctg gtatctacgc
    57541 tatcgaacgc atcctgcagc cgatgggtgt aaatgcccgc aatcaggccc gcgacgagta
    57601 catcaaaaaa tacgcccagc tcgacgatca acggcatgcc gtaggccgcc gccgtcgttc
    57661 ccaggaagac gccgttctcc atcaccagaa atccgaccat ttgcgtcacg gctttcttcc
    57721 tggcgatcat cgtaaacagg ccgatcaaaa tgatggcaag ggccagggcc agcgaatcgc
    57781 gagtcaggag ataccccagc ggaataatag gctgcgtgat gaaaaaggcc accaccacca
    57841 atccgccgca gatcaacagc ccggccggaa tgttgatatt catgaccagt tctcgcgaca
    57901 cattcagacg ctcgatgacc tttcggagaa tccgcggcaa cacgatcact ttgatgacca
    57961 cggtcagtgc cgcggctaga tagatgtgcc gatgcccggt caggaaggcg acgagcgccg
    58021 ccgtggtcgc caaaaagaac gattgcagcg cgaacagatc gacgcaagcc gagagccgcc
    58081 gctgcgccac gatggcgaag caactcaaca gcagcaacac cgagcagaga tcgacgagct
    58141 gcgacccgag ctgtgttgat tccgacatcg ccttaccctc gcaacgtgta gaagaacacc
    58201 aaggccagca gcgccag
//
LOCUS       DAOQPD010000017        57398 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_204_length_57398_cov_24.614617, whole genome shotgun sequence.
ACCESSION   DAOQPD010000017 DAOQPD010000000
VERSION     DAOQPD010000017.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 57398)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 57398)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57398
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_204_length_57398_cov_24.614617"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..234
                     /locus_tag="PK063_06065"
     CDS             <1..234
                     /locus_tag="PK063_06065"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96645.1"
                     /translation="EQRADLFRQSPVLSGRLRVSEQTLIPYIGAGFGGGYVTERDRAL
                     NPQPTLPQQNLFGEAMGKSMMPNEFQMGIRIPF"
     gene            complement(283..966)
                     /locus_tag="PK063_06070"
     CDS             complement(283..966)
                     /locus_tag="PK063_06070"
                     /inference="COORDINATES: protein motif:HMM:NF024811.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HMZ96646.1"
                     /translation="MRAIIFDFNGVIADDEMTHLECFQKALREAGLVLSKEDYYGTYL
                     GMDERTCAAAMLTRRDGTCDHTTLARIIERKAALFRTHTATHKPALFPWVTGFVQRAV
                     EQYRLAIASGGRREQIQSALAGHSIEATFEVMISADDCAVGKPDPAIYECALRQLAAK
                     RPKPPLLRADECLVIEDSRAGIQAGLRAGMRVLALATTYPASQLTEAHLVLPSLEGID
                     PSELARRLF"
     gene            1134..3158
                     /locus_tag="PK063_06075"
     CDS             1134..3158
                     /locus_tag="PK063_06075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HMZ96647.1"
                     /translation="MSDYAVLGDLLVIYAVSTAVVFVFHQFRLPSIAGFLVAGALIGP
                     HGLHLIPDVSQVQVLAEIGIVLLLFTIGMEFSSAHFASARRILAVAAPVQTGGVLILA
                     LLGALAVGLSYQQGIFWGFLLSLSSTAIVLKALSEQGESDSFHGRATVAILIFQDLAV
                     VPMMLITPILATPSGSAMGMVLLTLLKAAVVVVLIVAAAWYLVPRLLRHIVRSRSREL
                     FLLSIIVLCLGIAWLTSLGGLSLALGAFIAGLVMSESEYSHQALAEVLPFRDSFNSLF
                     FVSIGVLMDLRVVLDHPFIVLGLLVAVIAGKLLAGAGAMVASGAPPRSAVLVGVALAQ
                     VGEFSFILAQQGQEAGLFSGDHYQLFLAVSVLTMVVTPFVMQWSPHLGRRIEALQRVR
                     GWMPTRTVAHVEQLEGGQVRIKDHVIIVGYGLNGRNLARVLSETEIPHVALDLDGETV
                     RRESRHGVPIYYGDGSNANVLRHMKIEDAKVLVIALSDPFTARRTVKVAKGLNAKLHI
                     VVRTRYLRELEELHQLGADDVVPEEFETSIEIFALVLRTYCLPQEFVARKAEQIRREG
                     YALLRRSEMPELAHHLRGGTLTDVEVETCRVDEDAPAVGKSLTELSIRPRTGASVIAW
                     TRSQVTQSNPSETVRLQAGDVVTLLGSREQIRRAMALLNEPNHGTSHQLT"
     gene            complement(3217..>3504)
                     /locus_tag="PK063_06080"
     CDS             complement(3217..>3504)
                     /locus_tag="PK063_06080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic ring-hydroxylating dioxygenase subunit
                     alpha"
                     /protein_id="HMZ96648.1"
                     /translation="QCRIDFTAAWNILPWLPFAKPLFRYFANIFMKQDKQAMERQAVG
                     LKYKPALMLIDDADTPAKWYYKLKAAHLASVQTGRPLEHPLKGPVTLRWRS"
     assembly_gap    3505..3604
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<3605..4460)
                     /locus_tag="PK063_06085"
     CDS             complement(<3605..4460)
                     /locus_tag="PK063_06085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic ring-hydroxylating dioxygenase subunit
                     alpha"
                     /protein_id="HMZ96649.1"
                     /translation="MSTDLITELKPTKSAPLFGFWYPAATSSSLGVGQMQTQVMLGLP
                     ILICRDRQGQVAAMRDICPHRGMPLSFGHFDGERVECAYHGWQFDTGGRCRHIPALVE
                     GSALQPEKIGITSYPCRDEDGYVWVFLPDPQQPNQPVPELPRLPLPSAPYRMVQISTI
                     LDCTIDDGIVGLMDPAHGPFVHQSSWWRTQASMHDKAKTFEPIPNGFRMVPHAPSKNS
                     GPYKLLNKLYGGPLTTTIDFVLPNQRFEFVQCGSMFVSSRATVTPVGEQQCRIDFTAA
                     WNILPWLPF"
     gene            4686..5216
                     /locus_tag="PK063_06090"
     CDS             4686..5216
                     /locus_tag="PK063_06090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE/DsrF/DrsH-like family protein"
                     /protein_id="HMZ96650.1"
                     /translation="MTTAQIEPTAALAELRESKADRVTIVLLSGDLDKAMAAFIIATG
                     AAAMGMRVTVFFTFWGLNTIRKKGASSSASDWLRRMFGFLNKGGADTLPLSRFHFWGL
                     GTRMMQVVMKQNRMPGVPELMQMAIDLDVRFIACTTTMGLMGITKDTLIDGIDQFAGV
                     TTYLAEAKQGSVNLFI"
     gene            5235..5480
                     /locus_tag="PK063_06095"
     CDS             5235..5480
                     /locus_tag="PK063_06095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA family protein"
                     /protein_id="HMZ96651.1"
                     /translation="MIQADVKLDTLGYFCPMPIILTSKKIKELTMGQVLEVVSDDEGI
                     KKDMPAWCETTGHQMVGLEEEQSSSKRIYKAFVKKAK"
     gene            5618..7180
                     /gene="ftcD"
                     /locus_tag="PK063_06100"
     CDS             5618..7180
                     /gene="ftcD"
                     /locus_tag="PK063_06100"
                     /EC_number="2.1.2.5"
                     /inference="COORDINATES: protein motif:HMM:TIGR02024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030409 - glutamate formimidoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030412 - formimidoyltetrahydrofolate
                     cyclodeaminase activity [Evidence IEA];
                     GO_process: GO:0019556 - histidine catabolic process to
                     glutamate and formamide [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate formimidoyltransferase"
                     /protein_id="HMZ96652.1"
                     /translation="MSQVIECVPNFSEGRNPDVIQALVALVRSVPGVALLDESHDTDH
                     HRSVVTFAGRPYAVAEVAFQMARLASQLIDLRSHHGEHPRVGATDVMPFVPIREVSMQ
                     DCVQLARMVGQRIGNELKIPVFLYEQAAARPERVQLEWIRNGGLKGLADRMAADPAWV
                     PDFGPKQLHPTAGATIVGARWPLIAFNVNLKSGDLLVAKAIAKAVRQSSGGLPSVKAI
                     GVELRSQGLVQVSMNLTNYEETSLQVAFTAVEREAAARGVEVAGTEIIGLVPEQCLID
                     TAQRALRLDRFEGRQVLEMRLDSAESRAAIGRLAGSQPVKESPSLPAKPVASTNVLAA
                     EQGLTGGSVGALAASFAASLGTMVAKLNRARPAETRLTEIGTRFRELAQADRDAYARV
                     LKARKLPPNHPDRAVQIASGLLDAIETPMEIVKLCCEVIPLLRGLLAQAKPELQPDLK
                     MGIELADAAINGCVAMVEENMKVQPNQLLVASIRERFAVAEQMLVDAKSLCYTPPFDS
                     WSQNMLNILKLR"
     gene            7204..7398
                     /gene="rpsU"
                     /locus_tag="PK063_06105"
     CDS             7204..7398
                     /gene="rpsU"
                     /locus_tag="PK063_06105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010545388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HMZ96653.1"
                     /translation="MEIKVFNNNVEKALKVAKKKLAGEGLFRELKRRRYYEKPSVRKK
                     AKEREAQRRRQKWLAKRRPE"
     gene            7468..8127
                     /gene="nth"
                     /locus_tag="PK063_06110"
     CDS             7468..8127
                     /gene="nth"
                     /locus_tag="PK063_06110"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HMZ96654.1"
                     /translation="MQAHEIHAVIRTVKREIARWPDPVVGVVAKKSGRDPFLVLISCL
                     LSLRTKDKTTAEASARLFALASTPATMQQLSQSTVESAIYPVGFYRTKAKQIQQICRQ
                     LLDRYHGRVPDQIEALLTLPGVGRKTANLVVTVGYEKPGICVDIHVHRISNRWGYVKT
                     KTPDETEKALRGKLPRKYWITFNDLLVPFGQNLCQPVSPFCSRCKIAEYCDRVGVTKS
                     R"
     gene            complement(8186..8605)
                     /locus_tag="PK063_06115"
     CDS             complement(8186..8605)
                     /locus_tag="PK063_06115"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96655.1"
                     /translation="MADKPKFVLFAHNATYDKLHQVATLGLTASAMGKDVIVVLLFWT
                     IKKLAEGKIDHIDFPPEYAASAEEVARLLKEKKVPRISEMFHEARLVGQFRLIACSAG
                     LEYMGVEAGAVERNVDEVLGLPAILSLTAQAETKLFI"
     gene            complement(8611..8979)
                     /locus_tag="PK063_06120"
     CDS             complement(8611..8979)
                     /locus_tag="PK063_06120"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96656.1"
                     /translation="MLRTIRSSACRLAVLGLILVLNTVEVFDQGAQAADSAAPPELQI
                     DISKIGLGKEVVITQGNKEWFMRVEVTPENSVVVRQEKQGERYLLDESEMHDRAMTAA
                     EVDAAISDFINSVKTRQKVK"
     gene            9103..9531
                     /locus_tag="PK063_06125"
     CDS             9103..9531
                     /locus_tag="PK063_06125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PGPGW domain-containing protein"
                     /protein_id="HMZ96657.1"
                     /translation="MSDMLAQIESYVPASVLIWFAVSSVVMFVGTLIAIPVILMRLPA
                     DYFDTRIPRPWMENHHPVLRLLGHVVKNVVGAIFLFAGFLMLFLPGQGVLTMLIGLSL
                     IEFPGKRRVEAKIVGQSTVLSTINAMRAKFDKPPLIIAPE"
     gene            9595..12240
                     /gene="polA"
                     /locus_tag="PK063_06130"
     CDS             9595..12240
                     /gene="polA"
                     /locus_tag="PK063_06130"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: protein motif:HMM:NF004397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HMZ96658.1"
                     /translation="MPTLYLIDGSAYIYRAFFALPPLSNSKGLQTNAVYGFTTMLMKV
                     LRDHHPDYVAVVFDEKGPTHRHEAFKEYKAQRPPMPQGMSAQVPYIHRVVEALSLPVI
                     RQAGYEADDLIGTLARKGEGEGLDVVIVTSDKDMFQLLTPKTRIYDPVKDKWFGEADS
                     QVRFGVEPARVVEIMGLMGDTSDNIPGVKGIGEKTAVKLITQFGTIEELLRRVEEVTP
                     AKTKNLLLEQGESARMSRQLATIQVDCPIEFAPAHFQARAPQTEVLVSLLRELEFMTL
                     AKAFQGDTPEQNRLGAEVQRIHDTAGAEDFLKRRQPDTMMGLACVLSDEAGVRADIQG
                     CAFGWPDGTVAFVQGEAQDWPQPLTAYVRDGSRPKAVQDLKPTLLALQRQGIDMPGPY
                     FDTMVADYLLNPNRRAHTLEAIAMDLLSYQLGTGEREEGGKEPQSLFDVDERVVRRTG
                     EAAAVTAKVAPMLRDRLKEQGSLSLFEQVEMPLVPVLADIERNGFLLDVEGLRTLSKE
                     LERELEQMVGTIYRLGGGEFNIGSPKQLATVLFETLGLKPLRKTKTGFSTDEDTLTQL
                     ANQHELPAQILSYRTLTKLKSTYVDALPQLVNPDTKRLHTSLNQTVAATGRLSSTDPN
                     LQNIPVKGDYGLRIREAFIAPPGHHLLCADYSQVEPRILAHLSQDPRLLEVFEKGEDI
                     HMATAMEIFNLPAGDVTREMRRAAKSVVFGIVYGISPFGLASNIGVPQAEAKKYIETF
                     FEKFAAVRALMDHNINDGKTKGYTTTILGRRRPIPELQSGDPSQRGVGERMAVNSPIQ
                     GSAADLIKLAMIKVHRRLRDELPRCKMILQVHDELIFEVPDQELEQAKQLVKAEMEAT
                     GDALGLSVPLKVDVGVGCNWRAAHP"
     gene            12413..12799
                     /locus_tag="PK063_06135"
     CDS             12413..12799
                     /locus_tag="PK063_06135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallopeptidase family protein"
                     /protein_id="HMZ96659.1"
                     /translation="MSPRKRRLTIPEPEFQALVQQALDGLPDEYAKRITNVAVVVEDE
                     PSPEVLADLDMDEDEDLLGLYQGLPIDKESFFQAGGQLPAKISIYRGPILRLCRTKQE
                     VVQEVRDTVVHEIGHHFGFDDDEMPY"
     gene            12890..13729
                     /locus_tag="PK063_06140"
     CDS             12890..13729
                     /locus_tag="PK063_06140"
                     /inference="COORDINATES: protein motif:HMM:NF037404.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbiV family abortive infection protein"
                     /protein_id="HMZ96660.1"
                     /translation="MTAAKTFRLAAVAALTNANQLCAEARLLAENEHNSRAAALAVIG
                     LEEFAKAVACTVAAIFPEKSSDLGNRLNAHNVKQWIYQTFEGIQIQVQDWLNVVPYES
                     GAGSPIEPETILLETFRTLSKSRWGSVVPTKNSADSAAKQDQKYLNDPRMHARPTEIM
                     TTPFIKNVAFYVDVKKGEVLLPNRVDRYANYEIHGLTWSLEHSSPLKQILSDDHKWEA
                     FADAVRRTPGAGLSIEAEVLTPKKTAIKQLRRLPETATWDQIKKEIERGAQEATEERK
                     LTS"
     gene            complement(13750..15003)
                     /locus_tag="PK063_06145"
     CDS             complement(13750..15003)
                     /locus_tag="PK063_06145"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96661.1"
                     /translation="MPIENNFQHDELSRKNPGDRLTYADWTPPPDMDSPAWQAAMGEA
                     GQKLSQAGVRVIVFLHGAIPGTDIFGLGRLDEVGGLKRGYSRGISGLDSLLSFMREGT
                     NGITPLPGGMKPPLANDEATKSLLDSQIGDAGNFTAPIVERCRKALNQHVSKPIVCVR
                     ELWSSEHHHLGRALAACRLLDRLRALVTEHHLGTGDRILIQAHGQSGLVLALAANLLC
                     PSPITGRKAFFDLLLAANPQHSDVQAIQRIDPLLTSGSLLNGAALDIVTFGTPVRYGW
                     DPSGIGKLLHIVNHRNLRTDGKTWLSKMELPQISVEMPIAWGGDYVQELAVAGSDALP
                     AESAKAANKAVWELLEPYDGFERWVECARRATRFPSEGQCLLVDYKDCTSSTNVRDHY
                     YGHAAYTRANAILFNFNQIVGRLYS"
     gene            complement(15073..15618)
                     /locus_tag="PK063_06150"
     CDS             complement(15073..15618)
                     /locus_tag="PK063_06150"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="LPP20 family lipoprotein"
                     /protein_id="HMZ96662.1"
                     /translation="MPLTSSHILMAVGMAGTLLVATATMAGELTPQDVRTHADQHFQQ
                     LRAREQTIAPTTRDRPQQDPSSSYHPDQFFIGQGQGDLSKGKLVCQRVSELAARADIA
                     KQIRVQVKEHATDRLRERTGREPEQDIEVVREEIVQEYLQGVTIVDRRIDDEAKTCTA
                     VAVMPKATLHTSPAAESSARH"
     gene            complement(15621..16718)
                     /locus_tag="PK063_06155"
     CDS             complement(15621..16718)
                     /locus_tag="PK063_06155"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96663.1"
                     /translation="MTDWETRVDAIRLAAEQAKQQALEQVASYLESVTVVQNLDVTQD
                     ELRSYTAGMVLVLDQQVDTALDGDVVVIRVTLKAQVDSEEAAQAILAMKQNEDVRQEL
                     LALKEDVESLHKQLEDANQALAHANSPEQVRKLNQQRTDLLNHAESDAMVAQAWTDWL
                     LIAPFAHPYPSAGVAQVQALLGIAGRLNPTNPHLAIAQQTVGAKLPPAPPHPRQSPVP
                     HTVPFLPGYYVVPKEPAPPGTPPPTDSKQLSSVYQLNPLLPNPSGQPPQSGNSTTIIQ
                     AHPRPGTSPSVPDRNMMPTYRQIPAPNSQASHPTLHTYRAGGSPPSASIPGSADGGIR
                     GGRPPVIHQTKPLSPSESTAERGSATNQGDK"
     gene            17083..18132
                     /locus_tag="PK063_06160"
     CDS             17083..18132
                     /locus_tag="PK063_06160"
                     /inference="COORDINATES: protein motif:HMM:NF013799.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HMZ96664.1"
                     /translation="MSFIRNISTVPVAFCLAVVLSMTVVASSSSSVALAARGAGDIPP
                     SVPAGMTEHVILFVLEGFGQESLKSGVMPVLSSLVKEGAVTWSATAVAPARRLPTMAS
                     LVTGMPVAKHGITWNVFEFSRGYPRAPTVFDYLDLSGGRDSAIFYMDESLYQLAKPEP
                     YTDYQMCGPLRAECNPDRLVGYVRDYFKKATSGSGYGHAIPSLPHLLVVHLPAPGRVG
                     EAQGWKSAAYKDALKAVDKAMGTVLDLYRELGLMKRTTVFATSLSAFGETQFSSGDMS
                     ADQAGAVPVVPWIASGVGIKAGYAIRQPVSIIDTGATVMRALGLTTYTEWESHPVEEI
                     FKTAFTVAPVNPLLQ"
     gene            18140..18631
                     /locus_tag="PK063_06165"
     CDS             18140..18631
                     /locus_tag="PK063_06165"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96665.1"
                     /translation="MDILSHRLFTGRQTLIRIVALSCAVFAGHAERLLAAGPPPAYTK
                     EHTITIDPTPLVPQSWWQVPGITPPLWVLDPETSDAYRTTETRELHLKPGQYKFISFT
                     FDFPFTVSLDGKLEYSKSLDQCVEGRGTQTLVVRCKRTYPHGGQRDAYYGNSEVGDGT
                     GTR"
     gene            18612..19982
                     /locus_tag="PK063_06170"
     CDS             18612..19982
                     /locus_tag="PK063_06170"
                     /inference="COORDINATES: protein motif:HMM:NF025030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HMZ96666.1"
                     /translation="MAQALDDLLDSLEDPDDATREEAAKALAQLANPTTLDALIGACG
                     DEYWSVRTRAGWGVAKIGGPKAIEALIALFNDPIMEVRNEAVAAVVSLGVGHLDRLLV
                     AMKDERWRVREHAAKACGDLRDARAVDALIFACRDRDGAVKSAAAEALGKIGDAKAIP
                     ALIKLFRDSSKIVRETAGIALVAIGQPSVDLLLETMKDKDFVVRCHAARALGGMTTDY
                     QIGRSWVREPRVVDALIEALKDPDRAVREDATIALGMIGDPRAIDGLLEAMKDGAVKR
                     HAIASLGMIGDPRALPAVLAALKGKGVRQDGTPTPGCIVSEDAFIKEAAATALGHFRD
                     PRVIPDLIMLLKDGVLREKAAAALVLIGDSAIEPLISFLYDPKASEVEAEGERVLSYA
                     SVRLTAKDSLRLLVVETLEHLGWTPPDEETSVDSSQADNLRVDRPLGDIGRFGPSGDF
                     AKGSVR"
     gene            20163..21245
                     /locus_tag="PK063_06175"
     CDS             20163..21245
                     /locus_tag="PK063_06175"
                     /inference="COORDINATES: protein motif:HMM:NF025030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HMZ96667.1"
                     /translation="MADTVSEQIAALSDEDWAVREEAATLLGSLNDARAVLPLTHALR
                     DTDRAVREAAVGALSSLGSVSVPALAGCLADPALQVQEAASAILASLADARVLAPLMQ
                     ALGSRDWIVRMHAAKGLGRIGDPEAVSALMPLLQDKVKAVREEASTALAAIGVAAMAG
                     LIEALQHDDWLVRLHAVEALGKLKSPDSVEPLLRALFNERDSAIREDVVRALGAIRDG
                     RAVDYLVTVMKEPGLRLLAVEALGHIGDRRVVPILRRVVEGVPLGEPRDSATPCADGW
                     TDEMATMGMAARALGMIADAVAIPSLIVALRNTITRSEAAAALTKFGPAVIPSLLPML
                     AKEQDENVRYHVRETLTAVGWRAGRV"
     gene            21340..22440
                     /locus_tag="PK063_06180"
     CDS             21340..22440
                     /locus_tag="PK063_06180"
                     /inference="COORDINATES: protein motif:HMM:NF025030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HMZ96668.1"
                     /translation="MSKESIDTLVSELTHEEEWRRMRATAACLAGGPRAVQALTHALQ
                     SGDVPLRVEAAAMLSRIKDPAAGVALVTLIRDPEATVRQAAFAALEQMAGNLDDETAA
                     GLVRNLHESPDEEVRHRVRQLLGVIPNAITPLCEMLRHPDAEAQMTAATILEHLLDPR
                     SADGLIDAMASPAVREIVVRTLKKLSAVRERIDATFNALRDVEGASEREEARMATVMD
                     LLGIGRPSVEILIEYLEDDDWLIREAAADLLGKIGDVRAVEPLMKRLQKDKDTGVKEY
                     AVKSLGLIGDPRPAQLYIEAIPIRPLRVMAIEALAKIKDVEVLRPYNELFNRLRSDRD
                     GIVSYSAGLIADKLAALEGEQPVGQEESDDHE"
     gene            22433..23194
                     /locus_tag="PK063_06185"
     CDS             22433..23194
                     /locus_tag="PK063_06185"
                     /inference="COORDINATES: protein motif:HMM:NF025030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HMZ96669.1"
                     /translation="MSDAERIAQLIAALRDDNEALRDHAMASLGQMGIEAVPQLIGLM
                     ADEDVVIREAAATAVVRIGPIAFDQLLEALRDDEWAIREQAANVLGRFRDPRAIDPLM
                     VALKDKDGAVRTAAVWALERIGDSRATPGLIEALGDGTVREDVARVLKKIGDTRAVDA
                     LIGGLLGPNWMVRRHAAEALGKIGDPRSADALIQSLQDEDWLVRRNAAESLARLGAKH
                     AIEPLLPLLEDENTMVQETVEGVLASLGWKQATSS"
     gene            23215..23925
                     /locus_tag="PK063_06190"
     CDS             23215..23925
                     /locus_tag="PK063_06190"
                     /inference="COORDINATES: protein motif:HMM:NF025030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HMZ96670.1"
                     /translation="MAEEAPVKLIQIGPKGGPKKDGFNLVTERVVAVNPEARQLEVEL
                     LAYDGKTVVLDVGEEALEDFLKIKPGDGATIRVVEEGGKRVAKSFRIRAKDPNAAKAD
                     AMLIDLKDSHWLNRKYAAEVLGDLKDPRAVVPLVEALTDEVGDVRQRAYDSLIKIGGS
                     AVPSLVPLLASEEDDVRQSATEIIRKIGKPAVEPLATALAEADDRLKTKIMKVLDRMG
                     YKPKAKEGAQPEPAKLLS"
     gene            complement(23947..25266)
                     /locus_tag="PK063_06195"
     CDS             complement(23947..25266)
                     /locus_tag="PK063_06195"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HMZ96671.1"
                     /translation="MHISVIGTGYVGLVTGACFAEFGVNVTCMDTDARRIAKLEKGEV
                     PFFEPGITELVAKGIKEDRLHFTTDVAKAVDKALVIFIAVGTPPKSDGSADLSYVEEV
                     GRGIAKNMTGYKVIVTKSTVPVGTGEKLREVIKANQTGRFRFDIVSNPEFLREGSAIE
                     DFMRPNRVVIGADSEQAVAIMKDLYRPLYLLETPIVVTDIPTAEMIKYASNAFLAVKI
                     SFINEIATVCEKVGADVQLVSKGMGLDNRIGNKFLHAGPGFGGSCFPKDLAALVQTGE
                     RVGYPFQIAGAAAKVNYEQHLRMVQKVKDACGGVKGKTLGVLGLSFKPNTNDMREAPS
                     LTILSELMKEGAKIRAYDPASMEESMKLLPGMVPCQDTYEVAEGADGLIIMTEWNQFR
                     NLDFERLKKAMREPLLLDLRNTYESDRVVPFGFRHVSVGRPTKNPAA"
     gene            25464..25874
                     /locus_tag="PK063_06200"
     CDS             25464..25874
                     /locus_tag="PK063_06200"
                     /inference="COORDINATES: protein motif:HMM:NF012780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HMZ96672.1"
                     /translation="MVVAGGPIQRPLAMMMRPITKTVRPDDSLLVVAQQLRDARVGAM
                     LVADHGDYVGIVSEADLVRKAMASGAASDQVTVRSVMSAPLMTIDIAQSAHEASDVMA
                     ERGIRHLVITDEGRVVGMISVRDLLRYFKNWGTL"
     gene            25938..27512
                     /locus_tag="PK063_06205"
     CDS             25938..27512
                     /locus_tag="PK063_06205"
                     /inference="COORDINATES: protein motif:HMM:NF037959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused MFS/spermidine synthase"
                     /protein_id="HMZ96673.1"
                     /translation="MMAQRPAVVPIPRLFLLFTALVTGAIVMALEILGSRLLAPVFGN
                     SLFVWGALIGIILAAMSSGYAFGGWASDRYRVAAVLAWLLLGSGAWTLLMSWMGQGAI
                     FQVAKLVEDPRWGPSLAACVLLAPPAFGLSGVMPALLRLAVVDMGYLGRHTGSMIALS
                     TVGSLAGTWGTAFFLLSWLGTQTLVATLGVIQLLLGLLWLQQGSGRVTKLTGVVMTGL
                     LISGWQLFGQAPPVAGLVYQEDSPYQQVRVRDDDLFRYLVLDRTWHAVMWRSDPTALF
                     LPYSQLMVAAVALAPEPKRGLILGHGGGSLAKWLAQVWPELELDVVEFDPVVVRMAEQ
                     YFDYRPPANHHVSVKDARVFLRDTKATYDVIWVDAFARHLIPFHLTTVEFFSELRGRL
                     NPNGVLALNLASSGEGGDLQRANAVVQTLKSSFPSIESFGVKGPWRAHQTTAENLIFF
                     GGGPIATMSYDEIVKRIYMQVEARRLPLEAIALLASRRATPWPPGLTLTDDYTPYDLL
                     IGSHAVEMSPEGNSSP"
     gene            27787..28266
                     /locus_tag="PK063_06210"
     CDS             27787..28266
                     /locus_tag="PK063_06210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96674.1"
                     /translation="MGKTMVAVFFGLVMLMAGASGAYALQAGGVEIGDLDTGSVVGQP
                     FKELIVDAELYAVEIGNLKAWYPPVTVIDFKVRPGRPVVLKVTNNSSSEHGFQMTDPV
                     NAASPFVMKAEVVLKPGETKYIGVPTSDMFNATQGNTLTYRCHLHPAHVGGKLVMIK"
     gene            complement(28361..28696)
                     /locus_tag="PK063_06215"
     CDS             complement(28361..28696)
                     /locus_tag="PK063_06215"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96675.1"
                     /translation="MNCFTRLACIAILALAPLPSYAMTEVGDIGTIIESFITKQFPDA
                     ASHFWVVNDTQWDGDEMIVDMNTVVTDRREAPPTESRFLLLIVEGRLQGIQNIPLDAA
                     AECQKEQEV"
     gene            complement(28909..29256)
                     /locus_tag="PK063_06220"
     CDS             complement(28909..29256)
                     /locus_tag="PK063_06220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HMZ96676.1"
                     /translation="MALLITDECISCGACLPECPNEAIFETRSDAEGKGNHVGDGQGV
                     GDNIYVITHDRCTECVGHFDEPQCAAVCPVDNCCIADPAYPETTDVLLEKAKSLNPDK
                     EIDPAKVWSGVRN"
     gene            29504..30001
                     /locus_tag="PK063_06225"
     CDS             29504..30001
                     /locus_tag="PK063_06225"
                     /inference="COORDINATES: protein motif:HMM:NF014678.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF192 domain-containing protein"
                     /protein_id="HMZ96677.1"
                     /translation="MVTRASGSESEQRRKKIVTFVLLVILLISVSLFLGGPKESELII
                     VEFPNGKTMETEVASTPEKLLFGLAFREGLPADTGMLYIFESTGLHRVATRQFRIPVD
                     MLWIDESHHVVHILEQVQPCLQDPCPFYGPPPEPVRYLIEAEAGYAKRAGITIGMELK
                     FTLRM"
     gene            30026..30343
                     /locus_tag="PK063_06230"
     CDS             30026..30343
                     /locus_tag="PK063_06230"
                     /inference="COORDINATES: protein motif:HMM:NF025178.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rieske 2Fe-2S domain-containing protein"
                     /protein_id="HMZ96678.1"
                     /translation="MEGFQCVAKVEDIPPGQVKVVKVNERAIAVFNIEGHFHAIYNSC
                     PHEGGPLNKGRVKGHVVSCPWHDLAFDVRNGQGTDGGGYCVGSYDVRVEDGQIFVGGR
                     RKV"
     gene            30379..30711
                     /locus_tag="PK063_06235"
     CDS             30379..30711
                     /locus_tag="PK063_06235"
                     /inference="COORDINATES: protein motif:HMM:NF020950.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease inhibitor I42 family protein"
                     /protein_id="HMZ96679.1"
                     /translation="MSPLSKAVPTGTEQEPGAKVVKARVGLPVHIRLWEDRTRGELWV
                     PIYDAAVMPLVEDDFLRTASNNAVDQGQRSFEFKPSVAGTHRVVFEKRLGWKFTAEDR
                     QIFYVTAS"
     gene            30736..31575
                     /gene="dat"
                     /locus_tag="PK063_06240"
     CDS             30736..31575
                     /gene="dat"
                     /locus_tag="PK063_06240"
                     /EC_number="2.6.1.21"
                     /inference="COORDINATES: protein motif:HMM:TIGR01121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047810 - D-alanine:2-oxoglutarate
                     aminotransferase activity [Evidence IEA];
                     GO_process: GO:0019480 - L-alanine oxidation to pyruvate
                     via D-alanine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-amino-acid transaminase"
                     /protein_id="HMZ96680.1"
                     /translation="MPDIACVNGCFGPVAEAVVSIEDRGFQFGDGVYEVIRTYRGKPF
                     ALDEHLARFERSAQALHLSLGLTKDQWMALVQEGLRLSQFPETKIYLQVTRGQAPRDH
                     LFPASTVPTTVLTFRELHPLDASIRKAGVGAVTVDDIRWGRCDIKSVNLLANVLARQR
                     AKEAGVFEAILVRDGLVTEGSVSNVMVVRNGVVETAPEGHRILSGVTRAMVLELARKE
                     GLPVVETFVGREDLLAASEVFLTGTTVEVLPVVRIDGQPIGAGVPGPLSQRLSRRWEA
                     LVG"
     gene            31665..32186
                     /gene="rimP"
                     /locus_tag="PK063_06245"
     CDS             31665..32186
                     /gene="rimP"
                     /locus_tag="PK063_06245"
                     /inference="COORDINATES: protein motif:HMM:NF014617.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000028 - ribosomal small subunit assembly
                     [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HMZ96681.1"
                     /translation="MSDAGAVSAGKPLVKRAEALNLRVQEVAAPILQSHGLELVEAVC
                     VGQGPRTVIRVFIDKPGGISLTDCEQAHRSLSPALDVIDPFPHAYTLEISSPGLDRPL
                     RTAHDYRRLIGEPVTLKLREPIQSQWRLVGTVLEVEDGAVTLAIQQKKTTETIRVEFD
                     HIAVARRKVEFSK"
     gene            32228..33367
                     /gene="nusA"
                     /locus_tag="PK063_06250"
     CDS             32228..33367
                     /gene="nusA"
                     /locus_tag="PK063_06250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HMZ96682.1"
                     /translation="MNRELIAVIDEIGRQKGIDKARVIGAIESALQTAAKKRFGQAEN
                     IQVEIDSKTGEISVVSKKIIVDTVANPKAEISLKEAREYDEGAEVGDEIGSLIEMDEL
                     GRIAAQTAKQVIFQKVREAEWEAVQKEYSTRQGDLVNGIILGMERRNFLVDLGKTEAI
                     LPIQEQIPRETYRRGDRVKALLLEVRRTPKDVQVILSRSHPQFVAKMFELEVPEVGEK
                     IVEIKSIVREPGDRTKIAVSSRDKAVDPVGACVGIKGSRVQAVVRELRGEKIDIITWT
                     QDPRVFIAEALNPATIEKVGIDEEKKSALVVVADSQLSLAIGKNGQNVRLAARLTGWK
                     IDIISATEYEKEKAERDRDIKAALAEETEAQRQQDEARAAAQQAE"
     gene            33431..36016
                     /gene="infB"
                     /locus_tag="PK063_06255"
     CDS             33431..36016
                     /gene="infB"
                     /locus_tag="PK063_06255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HMZ96683.1"
                     /translation="MRVYELAKQLGMENRELIPELKRLGIPVASHSSALDDDSVRMAL
                     EKLGSKARAGETSSSGHEAKKMTRLPKESAGSHAAAHEEAPKPDKKRILIKKKREEGA
                     EDVAASLAAAEAVFAPAAPAAADAGVVDQAPLPGSEVSEAGPIEPVQAQEPEPPPPVV
                     ATSEDVTTKPSQAPVVTTPPVDPLAAIKKKSLVPDASESEAAAREKLKKAKKAPRTRE
                     EDEAKFKNDATRWGDLRAIPVQRREDRSKHIHHASPTEITKPRKKSVKLTAGVSVKEF
                     AELIGQRPADVVRKLMDMGQMVTFNQSINLEAASLIAEEYGARVEVSTEKVGEALLEE
                     AAQSSGEEHAVSRPPVVTIMGHVDHGKTSLLDAIRSTKVAEGEAGGITQHIGAYIVGV
                     HDKQVTFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTVEAIHHAKAAGVPL
                     IVAINKVDKPGANVDRVKNALTEHGLVAESWGGDTIMVEVSAKQRTGLDQLLEMILLQ
                     AEVLELKADPTRMAKGLVIEAKLDRGRGPIATVLVQSGTLHVGDAFVVGNFSGRVRAL
                     VTDTGKKTTEAGPSVPVEVIGLPGVPSAGDAFTIVKDERVAREIAQERAMKQRAADLA
                     GPAKVSLDDLFAKIQEGNVKELPIVIKADVQGSSEALAAAVEKMPAGAVKLRVMHTGV
                     GGITETDILLAAASKAIVIGFNIRPEPKAAALAEREGVDVRLYSIIYDALNDIRAAME
                     GLLEPTLKERILGRAEVRQMFTIPKAGLVAGCYVVDGVISRASVGVRVIRDSVVVYEG
                     KLGSLRRFKDDVREVQQGYECGITVENFNDLKAGDIIEAFAIDKVAAKLESAHRGTSP
                     QPHRA"
     gene            36013..36294
                     /locus_tag="PK063_06260"
     CDS             36013..36294
                     /locus_tag="PK063_06260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF503 domain-containing protein"
                     /protein_id="HMZ96684.1"
                     /translation="MIVGLCTVELFIPDGHSLKDKRQVLQSLKSRLRDKFNVSVAEVG
                     EQELWQKAILGLACVANESAHVNQVLDQAVNLIQGVPTIQLLRSRIELL"
     gene            36304..36702
                     /gene="rbfA"
                     /locus_tag="PK063_06265"
     CDS             36304..36702
                     /gene="rbfA"
                     /locus_tag="PK063_06265"
                     /inference="COORDINATES: protein motif:HMM:TIGR00082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HMZ96685.1"
                     /translation="MTKSTYSRAERVADQIRMEVADILMRKIKDPRVRSVTVTDVELT
                     KDLRIARVFVTTMEQNKDERLVFDGLAKASGFVRAELGRRLALRYLPELIFMKDVSGP
                     RADRVLALLDGLHLDETKEDRLPETPRTDV"
     gene            36706..37734
                     /gene="truB"
                     /locus_tag="PK063_06270"
     CDS             36706..37734
                     /gene="truB"
                     /locus_tag="PK063_06270"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: protein motif:HMM:TIGR00431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004730 - pseudouridylate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HMZ96686.1"
                     /translation="MMIASTESQTATMLQDGVLNVRKEAGWTSHDVVARVRGKLRGMK
                     LGHAGTLDPAATGVLPLLVGRGTRIAEYLLEWDKTYLAGLRLGETTDTQDATGTVLQR
                     SPITALTEARIRETIAGFEGRIQQVPPMYSAVKVGGVPLYKAARAGKDVARQPREVTV
                     FRLEVVSIQLPDVMLRVVCSKGTYIRTLCADIGEKLGVGGHMATLIRERVGPLMVEQS
                     LTVNEVETRLTQGTLAGSMLTLDEALVGLPVCIIGRETARQVVHGMAVPTADVLSWQG
                     LPTILPEASGGPIRIKDTAGRLLAIGTMPAGLGDQARMPGELSIAMSKVLVEDESQGS
                     SIANSIEE"
     gene            37741..38010
                     /gene="rpsO"
                     /locus_tag="PK063_06275"
     CDS             37741..38010
                     /gene="rpsO"
                     /locus_tag="PK063_06275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011275926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HMZ96687.1"
                     /translation="MALVKEVKTELMKNFQQHDKDTGSPEVQIAILTNRITYLTEHFK
                     LHKKDHHSRRGLLTLVGRRRRLLDYLRHVEEGRYRAVIERLGIRK"
     gene            38170..40287
                     /gene="pnp"
                     /locus_tag="PK063_06280"
     CDS             38170..40287
                     /gene="pnp"
                     /locus_tag="PK063_06280"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HMZ96688.1"
                     /translation="MKQVVDIELAGRRLTLETGRIAKQADGAIWATYGDTVVLATAVA
                     SQNAKPGVDFLPLTVDYQEKTYAAGKIPGGYFKREGRPSEREVLTSRLIDRPLRPLFP
                     EGYYFETQVITSVLSADKTGVSDVIAITAASAALAISSIPFNGPIAGVKIGRVNGQFV
                     VNPDLETLETSDLHLVVAGTADAVMMVEAGANELPEATMLEAIELAHSEIKKIVAKIE
                     ELRALAGKPKRVVTQEPIDAALAEQVRKLVAGPIREAILIPNKSARQERLDQVLAETL
                     VALKSEEPNRDRHVKIIFHGLEYTEVRNMILEKRVRADGRGPSDIRPITCEVSVLPRA
                     HGSAVFTRGETQSLAVVTLGTTDDEQRIDALEGEYMRTFMLHYNFPPFSVGEARPLRS
                     PGRREVGHGALAERALKSIIPGKDKFPYTVRIVSEILESNGSSSMATVCGGTLALLDA
                     GVPIKEPVAGIAMGLIKEGDQVLVLSDILGLEDHLGDMDFKVTGTKNGVTALQMDIKI
                     GGIDAALMREALAQAKAGRLHILGCMAQALTAPRAKLSAFAPRIFPMKIKQDKIRDVI
                     GPGGKMIRSIIAETGVKINVEDTGDVTIASSDEASAQKAIDMIKRLTEEVEVGKIYLG
                     TVRKIMDFGAFVEVLPGTDGLVHISQLAHHRVKAVTDEVKEGDQIQVKVLEIDKQGKI
                     RLSRKEAMPAPAGSPATEPTPAG"
     gene            40294..41547
                     /locus_tag="PK063_06285"
     CDS             40294..41547
                     /locus_tag="PK063_06285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pitrilysin family protein"
                     /protein_id="HMZ96689.1"
                     /translation="MYRKIVLDNKLRVVAELLPTLKSVTIGIWVNVGSRDEQPGEEGL
                     SHFLEHMFFKGTRSRSATQISREIDALGGEMNAFTTRETTTFYVKVLDQQLEAALELL
                     SDLFYRSRFESKEVEKEKQVVLEEIRMVQDDPEDLVQELHMKHTLGSHPLGRPILGQA
                     PRIQALGRQDLVSYVGSHYDPERTVVAVAGNFTWKRLEQLLARYFSAPHKGVAVKQSR
                     RPPEVRGGVLVRRKALEQVHLCLGLQGLGAGHKDRYAAHALNGVLGGSVSSRLFQEVR
                     EKRGLVYSIYSFLSTYSDGGMTTVYAGTRPKEVERVVEVVCRELKKLRSKGIDAKDLA
                     RVKNQMKGSLMLSLESSHSRMSKLAKDELTQGSHVSLEQMIGEIDRVTTDQVYRVAQT
                     LLDQRCLAITALGPIPVNSLQSFAS"
     gene            41920..42432
                     /locus_tag="PK063_06290"
     CDS             41920..42432
                     /locus_tag="PK063_06290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96690.1"
                     /translation="MNRVGILAALAVSSVVGLLTAGVSMAADAPAGGGPSEVTTGSGK
                     FFKGEPTNTLKGRVWSQWADNPDGEILFGIQYWNTGDPASGEGGGRSSTSMDVKPPDP
                     LFTCCAWGYTGGTDKNNPYAGWHHAQTTVRLAVKDKGLMDQIIKASQELVAMEVTLDG
                     RTITGFKVLK"
     gene            42490..43164
                     /locus_tag="PK063_06295"
     CDS             42490..43164
                     /locus_tag="PK063_06295"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96691.1"
                     /translation="MMKLQKQGWTFMAAAALVVSFASTALAIEAFQERFEWGDLSKPT
                     TLQGRVIILDPYDEAVWLNIAVFGGNAESGLWWQRVHPGKNLKFYPADKNVWEQLKSM
                     ARAHSGPAAAKEVPPGSPTTLVEFVAQETEQNHRVITSVKKLNDNAGEMGKPKSISSL
                     RLKECEGKTEVDAACHAAKTLLNTSPKTPDGANLPLQYDVLLPDGKPIANLIPWTAKY
                     NQGSKH"
     gene            complement(43271..45919)
                     /gene="mutS"
                     /locus_tag="PK063_06300"
     CDS             complement(43271..45919)
                     /gene="mutS"
                     /locus_tag="PK063_06300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HMZ96692.1"
                     /translation="MGEADGTPLMRQYREIKQAYRDAILFFRVGDFYEMFQEDAVEAS
                     KLLSIALTSRDKSSETPIPLCGVPYHAATNYIAKLLRAGRTVALCEQVEDPKLAKGLV
                     RREVVRLYTPGTLIDSEFLPSSESNLLAAVAIRLRPATHEPTGCSFGLATLEVSTGEY
                     WLCEFHGPQAQIALMDELARLDPKELLYAEGCTPGAQSWIAELIGPRCCAQPATWFEL
                     DTGRAMLQEHFRVHSLDSFGCQQLTLGIQAGAAVLRYVRETQPSASLDHIRNLRVRQP
                     HDAMHLDSVTIRNLELVKPAGRWDDAPNHRSPYTLLGVLDRTVTAMGSRLLREWLLRP
                     LINCAPIEARLTAVEELKESIEPRVRLRTALRTVQDISRLCSRISLGVANPRDLLALK
                     LSLSSLPAIQAELTPLQAPLLAELSASWDNAQDLYELIEQAILADAPVSIRDGGILKD
                     GYHPDVDELRKATREGKGWIAGLEAKERERTGAESLKIRYNQVFGYYIELTKANLGKV
                     PSDYIRKQTLVNAERFMTAELKELEERVTGADAKLVALEQSLFEQLRTGLAAETARLQ
                     EISRRLAVLDVLTALAETAGLNRYVRPTIDTGDVLHIKQGRHPVVERLDLSGGFIPND
                     THLDLHTSRLHILTGPNMAGKSTYLRQVALIALMAQIGSFVPAAEARIGLVDRIFTRV
                     GASDNLAGGQSTFMVEMTESAHILHCATARSLILLDEIGRGTSTYDGLSIAWAIAEFI
                     QDPQRLGARTLFATHYHEMTQLEGLRAGITNYSVAVKERDGKVLFLRKIVQGGADRSY
                     GIHVAQLAGLPDAVIQRAKAVLAQLESTTAPRPILESQQALQFDSTLPAPHPMLEEVR
                     QMDLFSMTPLDALNRLAALQQRLLSE"
     gene            complement(45912..46256)
                     /locus_tag="PK063_06305"
     CDS             complement(45912..46256)
                     /locus_tag="PK063_06305"
                     /inference="COORDINATES: protein motif:HMM:NF018058.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LapA family protein"
                     /protein_id="HMZ96693.1"
                     /translation="MIRLILVGTVLLLALSFFLQNQEQEVTLRYFFGLRSASILIYKP
                     ILAAFGVGLLVSGILLFPAWVRGRIELRRKTKALQEAEVDLERLRQALDKAARRVGSS
                     SDIPTEGEPVDG"
     gene            46413..46553
                     /locus_tag="PK063_06310"
     CDS             46413..46553
                     /locus_tag="PK063_06310"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96694.1"
                     /translation="MGKINLKPIMRKPCAPAFGPFNSENSAAVYVVTQARILELGGSE
                     AV"
     gene            complement(46846..48390)
                     /locus_tag="PK063_06315"
     CDS             complement(46846..48390)
                     /locus_tag="PK063_06315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052855 - ADP-dependent NAD(P)H-hydrate
                     dehydratase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HMZ96695.1"
                     /translation="MTAEQMRALDHRTITEAQVPSLVLMERAGTGVVTHLEARYGSVA
                     GKKIVILCGKGNNGGDGFVVARLLRRKKARVHVLLLAPVAELSRDAKAMYQRFHRTAG
                     PSSITRPSDTNAIQQRLTPSEIIIDAILGTGLSTPVTGLYRDAIDAINAAGRLTVAVD
                     LPSGLHADTGSVLGTAVKADLTVTFGLPKAGLYCGGGIDCAGLVRLADIGIPSSFVDA
                     VGSRLLLLTAASANAALPPRHPSSHKGTYGHLGIIAGSVGKTGAAAMAAMAALRIGTG
                     LVTAAVPSSVNDILEAKLLEAMTLPMPETKARTFARSGLDRLLAFAGPRDAVAIGPGL
                     TTHPETVDLVQEFVKRIDKPCVLDADALNALAGKASLLTECPRPPIITPHPGEMARLE
                     AEATTQSVNEDRLGTATRFARERGVFVVLKGARTVIARPDGVAAICPTGNPGMATAGT
                     GDVLTGMVGGLLAQGVAPWDAACAATYFHGLAGDLAAQQLGQAGMIARDLIRHIPHAI
                     APTTHL"
     gene            complement(48462..49175)
                     /locus_tag="PK063_06320"
     CDS             complement(48462..49175)
                     /locus_tag="PK063_06320"
                     /EC_number="2.6.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033856 - pyridoxine 5'-phosphate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 5'-phosphate synthase"
                     /protein_id="HMZ96696.1"
                     /translation="MARLGVNIDHVATLRQARGGTDPDPLTAAILVELAGADGLVVHL
                     REDRRHIQDRDLTILREIVRTKLDLEMAADDAMAKIALSVKPDLVTLVPERRQELTTE
                     GGLDVANHRERIQKIVDLLRDGGIPTSLFIEPSLDQIKAAHKIGAAYVELHTGRYANA
                     NRSKEEDEEFEAITQAAKLAYKLGLGVNAGHGLTYKNVKRLAKLPEIVEFNIGHSIIA
                     RSVMVGLVQAVREMKELVA"
     gene            49477..50673
                     /gene="alaC"
                     /locus_tag="PK063_06325"
     CDS             49477..50673
                     /gene="alaC"
                     /locus_tag="PK063_06325"
                     /EC_number="2.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine transaminase"
                     /protein_id="HMZ96697.1"
                     /translation="MSISDGFYRIKRLPPYVFAQVQSLKLEARQRGEDIIDFGMGNPD
                     QPTPPHIVDKLIEASRKAKNHRYSASRGITKLRHAITGWYKRNYDVDLDPETEAIVTI
                     GSKEGLAHLALATIGPGDVVLTPTPTYPIHMYSFIIAGGEVRGIELRQDSDFFDDLLR
                     VYRQTLPRPRILVINFPHNPTTAVVDLEFFKKIVAFAKEHDVIVIHDLAYADIAFDGY
                     KAPSFLQVPEAKDVGVEFYTLSKAYNMPGWRVGFCVGNREVVGALAKLKSYLDYGIFQ
                     PIQIASTVALNGPQDCVKDVVQRYQNRRNVLVNGLNRIGWPVALPRATMFVWARIPDP
                     FRHMGSLEFSKLLLREAKVAVSPGIGFGEGGDEFVRFALVENEHRTRQALRGIRKVLN
                     LDDQEP"
     gene            50670..51983
                     /locus_tag="PK063_06330"
     CDS             50670..51983
                     /locus_tag="PK063_06330"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HMZ96698.1"
                     /translation="MKTEIGVGLIGFGTVGTGVARVLIENAELIRRRVGVPIKLVRIA
                     DLDITRDRGVAIPSGVLTTDIQQVLEDPRVDIVIELMGGYDLAKRVILDAVQRGKHVV
                     TANKALLAVHGEEIFAAASRRGIDLGFEASVGGGIPVIRALMEGLAANNIQSIYGIIN
                     GTSNYILSRMTSEGQRFEVVLDEAKRAGYAEADPTFDVAGIDSAHKLTIMVSLAYGTP
                     VNFKEIYTEGITGLTPLDIAYAKEFGFTIKLLAIAKCSDGEIEARVHPTMVPSASQIA
                     KVDGVYNAIQLVGDAVEDVVLYGRGAGSMPTGSAVVSDVMSIARDLLKDATGRVPPAS
                     YQPDYRRPLRIRPMEEITSLYYIRFMVLDRPGVLSQIAGVLGRYSISISSVLQQGRKE
                     GQTVPVVIMTHMAKERDIQHALREINPMPYISEPTTLIRVEGKDE"
     gene            52031..53089
                     /gene="thrC"
                     /locus_tag="PK063_06335"
     CDS             52031..53089
                     /gene="thrC"
                     /locus_tag="PK063_06335"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HMZ96699.1"
                     /translation="MTRWRGIIEEYRKFLPVTAQTPVITLGEGNTPLIRATRLAKKIA
                     PGVDLYLKYEGMNPTGSFKDRGMTMAISKAVEGGARAVICASTGNTSASAAAYGARAG
                     IAVYVLIPAGKIALGKLSQAMMHQATVIQVEGNFDQALTIVKELSATYPVELVNSLNP
                     YRIEGQKTAAMEICDDLGDAPTVHVLPVGNAGNITAYWNGYREYRAANQTTRLPRMMG
                     FQAAGAAPIVLGHVVKEPQTVATAIRIGNPASWQSALTAVKESSGAIDMVTDEEILHA
                     YALVAREEGVFCEPASATSVAGVIKLSQAGQLKEGATVVCTLTGHGLKDADTAIGISR
                     QPQTVKATRDDVARLLHV"
     gene            53108..54358
                     /gene="apgM"
                     /locus_tag="PK063_06340"
     CDS             53108..54358
                     /gene="apgM"
                     /locus_tag="PK063_06340"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: protein motif:HMM:TIGR00306.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046537 -
                     2,3-bisphosphoglycerate-independent phosphoglycerate
                     mutase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HMZ96700.1"
                     /translation="MKYLILHADGMADLACAELGGSTPLQAAKTPFLDQIAQRGEVGL
                     LSLPSDAGRTGSDVTGVAVLGYDPKKYYPGPGPLEAAGLGVTVGEQDVVFRCTMVTVR
                     GESASGGTDRAADIKKLGPHVVMEDATAGLIETEQARELVEAVNEQLGSESIQFYPGS
                     GHRHLMVWVGGKSRATCVDPQQLVGQSIAEALPAGDGADVLRKIMDASFFILRDHPVN
                     EEREEDGLKPANCLWLWGQGRAPLWPPLPERYQVSGVVVSASDVHRGVGLCAGLDAAE
                     LPAESGDESETFAGCVKAVVQELAKKDFVYLHAGLSDDVLHATNVHDKVQAIERFDAQ
                     VIGPILSALAKYPAYRLLVVCDPGLAKGQGSDVPPILYALCDGATQPPAGSSTRFHEQ
                     DKTIAGSAPRDATKLMMRLFPRGA"
     gene            54364..55599
                     /locus_tag="PK063_06345"
     CDS             54364..55599
                     /locus_tag="PK063_06345"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HMZ96701.1"
                     /translation="MALIVQKYGGTSVGNIERIHRVAERVERAQKDGHQVVVVLSAMS
                     GETDRLLKLAHEATHSPDERELDMLLSTGERVTIALLAMELRGRGVNARSFTGRQVGI
                     HTDSAHTKARISRVTAERIKEALAAGVIPVVAGFQGINASSDVTTLGRGGSDLTAVAL
                     AAALKADRCIIYTDVDGVYTADPNIVPAARRLDKISYEEMLEMASLGAKVLQSRSVEF
                     AAKYSVPVEVNSSFKEGKGTLVTREDADMEGVMVSGVTGDRNQAKLTIVGVPDRPGIA
                     ARVFGAVANANIVVDMIIQNVSQASMTDISFTVPKADLRNAVDLVQRLSQEIGARSVA
                     VTESIAKVSLIGVGMRSHSGVAAKMFEVLSREGVNIMMISTSEIKISCVIEEKYLELA
                     MRTLHTAFGLDRVSAPALG"
     gene            55674..57317
                     /gene="cimA"
                     /locus_tag="PK063_06350"
     CDS             55674..57317
                     /gene="cimA"
                     /locus_tag="PK063_06350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043714 - (R)-citramalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citramalate synthase"
                     /protein_id="HMZ96702.1"
                     /translation="MKRRTTASRRSSAPDSTTAPTLTAAQASALEIYDTTLRDGAQAE
                     DVSFSVEDKLRVAQQLDELGVHFIEGGWPGANPKDIEFFRQIKTMPFRNATVVAFGST
                     RKASNPVRKDKNLQALLDSGTQTITLFGKSWSFQVTDALGIALAKNLELIEDSIHYLR
                     SKDRRVFYDAEHFFDGYKANPDYALQTIRRAIAGGAERVILCDTNGGTMPWEIREICR
                     IVKQECPVPLGIHAHNDSEMAVANSLVAVESGILQVQGTINGIGERCGNANLCSIIPN
                     LQLKMQRPALGNKLTRLKDVSGFVTEIANLMPNKRQPYVGDAAFAHKGGVHIHAVLKN
                     AATYEHIDPAVVGNRRRILVSDYAGRSGLMEKVEAYGISLTKNHAKLQELVETLKERE
                     SQGYQFEGAEGSFELLMRKAMGSHRPSFQLLGFRVIVEKKQEHGLLLSEATVMVKVGD
                     VVEHTAAVGAGPVNALDHALRKALEKFYPQLREVKLLDYKVRVLSADKGTESKVRVLI
                     ESGDHKDKWGTVGVSENIMEASWQALADSIEYKLLLAGR"
BASE COUNT        11875 a        15133 c        17924 g        12366 t
ORIGIN      
        1 gaacagcgcg cggacctgtt ccggcaatcg cctgtgttga gcgggcgatt acgtgtcagc
       61 gaacagacgt tgattccata catcggcgcc gggttcggtg gggggtacgt gacggagcgt
      121 gatcgggcct tgaatccgca gccgaccttg ccgcagcaaa atctcttcgg cgaggctatg
      181 ggcaaaagca tgatgccgaa cgagtttcag atgggcattc gcattccctt ctaatcctgc
      241 cggttctgtt cgccctgtcg agtaagactt tctcatcact ggttagaaca gccgccgggc
      301 caactctgac ggatcgattc cttccaggct cggtaggaca agatgcgctt cggtcagctg
      361 tgatgccggg taggttgtcg ccagggcgag cacgcgcatc cctgcccgta agcccgcctg
      421 aatgcctgca cgggaatcct cgatcaccag gcactcatcg gctcgcagga ggggcggttt
      481 gggtcgcttg gcagcgagtt gccgaagcgc acattcgtaa atcgcgggat cgggcttacc
      541 gacggcgcag tcatcggcgg agatcattac ctcaaacgta gcctcgatgg aatgaccggc
      601 gagagccgac tggatctgtt ctctcctgcc gcccgacgcg attgccagcc ggtactgctc
      661 aactgcccgc tgcacgaagc cggtcaccca gggaaacaat gcgggtttgt gcgtcgctgt
      721 gtgggttcga aaaagtgccg cttttcgttc gatgattcgg gccagggtgg tgtggtcaca
      781 agtgccgtcc cgtctggtga gcatcgcggc tgcgcaggtc cgttcatcca tgccgaggta
      841 ggttccgtaa tagtcctcct tgctcaggac gagtccagcc tcgcgcaacg ccttctgaaa
      901 acattccagg tgcgtcatct catcgtcggc gatgacgcca ttgaagtcga aaatgatcgc
      961 gcgcaagatc cctccgtaac gtctctccaa tgtgccgcta agcgcgtcac gttagctgag
     1021 tttcctggtg cgggacaagc agaactcctt gttccattga gatccctacg gtatgctgcg
     1081 tcacgaatgc gtccaacctc cgatgtaact gattgtccaa atcttgtgac tctatgagtg
     1141 attacgcggt tctcggcgat ttattggtga tctatgcggt ctcgaccgca gtggtgttcg
     1201 tctttcacca gttccggttg ccgtcgatcg ctgggtttct ggtggcgggc gcgctcattg
     1261 gtccacatgg gttacatctc attcccgatg tgtctcaagt gcaggtgttg gccgaaatcg
     1321 gcatcgtctt attgctcttc acgatcggca tggagttttc ctcggcacac tttgcctcag
     1381 cccgccgcat tctcgcggtg gccgcgccgg tgcaaaccgg aggggtgctc atcctggccc
     1441 tgctcggggc gttggccgtg gggctctcct atcagcaggg catcttctgg ggctttctcc
     1501 tgtcgctcag tagtacggcc atcgtgctga aagccctgtc cgagcagggc gagagtgatt
     1561 cgtttcacgg ccgtgccacc gtggccattt tgattttcca ggacctggct gtcgtgccga
     1621 tgatgctcat caccccgatc ctggcgacgc ccagcgggag tgccatggga atggtgttgc
     1681 tcactctgct caaggcggcg gtcgtagtgg tgttgatcgt cgctgcggcc tggtatctcg
     1741 tgccgcgatt attgcggcat atcgtgcgaa gtcgcagccg tgagctcttc ctgctctcca
     1801 ttatcgtgct ctgtctcggt attgcctggc tgacgtcgtt gggaggattg tccctggcct
     1861 tgggcgcatt tatcgccggg ttggtgatgt ccgaatcaga gtacagccat caggcgttgg
     1921 ccgaggtgct gccgtttcgc gacagtttca atagtttgtt tttcgtgtct atcggcgtgt
     1981 tgatggatct acgggtggtg ttggaccatc cgttcattgt gctggggctt ctggtggctg
     2041 tcattgcggg gaagctgctg gccggcgccg gagcgatggt ggcatccggc gcgccgccca
     2101 ggtcggccgt gctggtcggc gttgcgctcg cgcaggtcgg agaattcagt ttcattctcg
     2161 cgcagcaggg ccaggaggcc ggcttgttct ccggggatca ctatcagtta tttcttgctg
     2221 tgtccgtgct cacaatggtg gtgacgccgt ttgtgatgca atggtcgcct cacctgggcc
     2281 ggcggatcga agcgctgcaa cgagttcgtg gctggatgcc cacccgcacg gtggcgcacg
     2341 tcgagcaatt ggaggggggg caggtccgga tcaaggatca tgtgatcatc gtgggatacg
     2401 gcctcaatgg tcgcaatctt gcccgcgtgt tgagcgaaac cgaaatccct catgtggcgc
     2461 tcgatctgga tggcgaaacg gtgcgccggg agtcgcgcca tggcgtcccg atttattacg
     2521 gcgatggctc gaatgcgaat gtcctccggc acatgaaaat cgaggacgcg aaggtcctcg
     2581 tgattgctct atccgatcca tttacggctc gaagaacggt gaaagtcgcg aagggcctca
     2641 atgcgaagct acacatcgtg gtgcggacgc gatacctgcg ggagctggaa gaactgcatc
     2701 agctgggggc ggatgacgtg gtgccggagg agttcgagac gtcgattgaa atttttgccc
     2761 tggtattgcg cacctattgt ctcccgcagg aattcgtggc cagaaaagct gaacaaatca
     2821 ggcgggaggg gtatgccctg ctgcgtcgca gtgaaatgcc ggaattggcg catcatttgc
     2881 gcggggggac gctgaccgat gtcgaggtgg aaacctgccg ggttgacgaa gacgctcccg
     2941 ccgtgggcaa atcgttaaca gagttgtcga ttcgtccgcg aaccggcgcc tcggtgatcg
     3001 cctggactcg cagtcaggtc acgcaatcga acccgtctga aaccgtgcgg ctccaagccg
     3061 gcgacgtcgt gacgttgctg ggatcgcggg agcaaatccg ccgggccatg gcgctcttga
     3121 acgagcccaa ccacggaacg agccaccaac tcacctagcg ccctcagcgc gcaggtcttg
     3181 tcaggtaccg cccacttcag gcagccgagg ctgttgctag cttctccacc gcagtgtgac
     3241 cggacctttg agcggatgct ccaacggacg tccggtttgc acggaagcga gatgggcggc
     3301 tttcagcttg tagtaccact tggccggggt gtcggcgtcg tcgatcagca tgagtgcagg
     3361 tttgtacttc aggccaacag cctgtcgctc catggcctgt ttatcctgct tcatgaagat
     3421 attcgcgaaa tatcggaaca ggggtttggc gaaggggagc cagggaagga tattccaggc
     3481 ggcggtgaaa tcgatccggc attgnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3601 nnnncgaagg ggagccaggg aaggatattc caggcggcgg tgaaatcgat ccggcattgt
     3661 tgctcaccga ccggcgtcac ggtcgcgcgc gatgagacaa acatcgaccc gcattgcacg
     3721 aactcaaacc gctgattggg caacacgaag tcgatggtgg tggtcagggg gcctccgtag
     3781 agtttgttga gcagcttgta ggggccgctg tttttcgaag gtgcatgggg taccatccga
     3841 aatccattgg ggatgggttc gaaggttttg gctttgtcat gcatgctggc ctgcgtccgc
     3901 caccaggaac tttggtggac gaaggggcca tgggctggat ccataaggcc gacgatgccg
     3961 tcgtcgatgg tgcaatcgag gatggtagag atctgcacca tgcggtaggg cgcggatggc
     4021 aacggcagac gcggcagttc cggcaccggt tgattgggct gttgcggatc ggggagaaag
     4081 acccacacgt atccatcttc atcccggcag ggataggacg tgatgccgat tttctccggt
     4141 tgaagtgcgg agccttcgac caaagcgggg atatggcggc agcggccgcc cgtgtcgaat
     4201 tgccagccat gatacgcaca ttcgacgcgc tcgccgtcaa aatggccaaa tgacagcggc
     4261 attccgcgat ggggacaaat atcgcgcatg gctgcgacct gcccctggcg atcacggcag
     4321 atgaggatgg gcaatcccaa catgacctgc gtctgcatct gtccgacgcc caaggaactg
     4381 ctcgtagcgg ctggatacca gaagccgaat aacggcgcac ttttcgtggg tttcagttcg
     4441 gtgatgaggt ctgtgctcat ggataaccgg gatatggcca gggtcttcgc ggacgagtgg
     4501 actataacgg cgggtctgca acaggtcaag caatggatcg caaggggaaa cgtctgcagt
     4561 gctgcgtcag gagcgccggg gagcgccgtt acggcttcgc gtttcttgac aaaaaaaaga
     4621 agtggagact atagtcattt ttgatgcgaa ttcagtcgtg tgtgctcaga caggcgaggt
     4681 aatccatgac gaccgcacaa atagagccca cagccgccct ggcggaactc cgggagtcga
     4741 aggctgaccg cgtcaccatc gtgctcctca gcggagatct cgataaagcg atggcggcgt
     4801 tcatcatcgc gacgggcgcc gccgcgatgg ggatgcgcgt gacggtattt tttaccttct
     4861 gggggctcaa cacgattcgc aaaaaggggg cgagcagttc cgcgtcggat tggcttcgtc
     4921 gcatgttcgg cttcctcaat aaaggcggcg ccgacacatt gcccttgtcc cgttttcatt
     4981 tctgggggct gggcacgagg atgatgcagg tcgtcatgaa gcagaatcgt atgcccggcg
     5041 tgccggagtt gatgcaaatg gcgatagatc tcgatgtgcg ctttattgcc tgcaccacaa
     5101 ccatgggctt gatgggaatc acgaaagata cgttgatcga cggaatcgac caatttgccg
     5161 gtgtcaccac ctacctggcg gaagccaagc agggcagtgt caatctgttt atctaagcgg
     5221 gctgaggaga gggcatgata caggctgatg tgaaactcga tacgctgggg tacttctgcc
     5281 cgatgccgat tattttgacc tcgaagaaga tcaaggaact gaccatgggt caggtgctgg
     5341 aagtcgtctc ggacgacgaa ggcatcaaga aagatatgcc ggcctggtgt gagacgaccg
     5401 gccatcaaat ggtgggattg gaagaggagc aaagttcttc caaacggatt tacaaagcct
     5461 ttgtcaaaaa ggccaagtag cactcagcga caggcgcgcg gatgcgaagc cgtcatgttt
     5521 tgccaagccg gagggtatgg tcgcctgcct ccggcttttt tttgtctgag actgtcctgg
     5581 ccgtaagtcg gccctgcaca ccagaagaag gaatgccgtg agtcaggtga tcgaatgtgt
     5641 gccgaatttt agtgagggcc ggaacccgga cgtcatccag gccctcgtgg ccctggttcg
     5701 atccgtccca ggcgtagcct tgctggatga gtcgcacgat acggatcatc atcgttcggt
     5761 ggtcaccttt gccggacggc cctatgccgt cgccgaagtg gcctttcaaa tggcgcgact
     5821 cgcttctcag ctgatcgatc tgcggagcca tcatggtgaa catccgcgcg tgggcgccac
     5881 ggatgtgatg ccgttcgttc cgattcgcga ggtcagcatg caggattgtg tacaattggc
     5941 tcgcatggtc ggccagcgca ttggcaatga gctgaaaatc cccgtgtttc tctacgagca
     6001 ggcggcggcg aggccggagc gcgtccagct ggaatggatc cgaaacggtg gcctgaaggg
     6061 actggccgac cggatggccg cggacccggc ctgggtgccc gacttcggtc cgaagcagct
     6121 gcatcccacc gccggcgcta cgatagtcgg cgcgcggtgg ccgctcatcg cctttaacgt
     6181 caatctgaag agtggggacc tgttagttgc caaggcgatc gcgaaggctg ttcggcagtc
     6241 gagtggaggt cttccttcgg tgaaagcgat cggggttgaa ctgaggagcc aggggctcgt
     6301 ccaggtctcg atgaatctga cgaactatga ggaaacctcg ctgcaggtgg cctttaccgc
     6361 ggtggagcgg gaagcggcag ctcgcggagt ggaagtggcg gggacggaga ttatcggtct
     6421 ggttcctgag caatgcctca tcgataccgc gcagcgggcg cttcgtctcg atcgatttga
     6481 aggcaggcag gtcctcgaaa tgcgattgga cagtgccgaa tcgcgcgcag ccatcgggag
     6541 gctggccggg tcgcaaccgg tgaaggagtc accgtcgttg cccgcgaagc ccgtcgcatc
     6601 gacgaatgtt cttgccgctg agcaaggatt gacgggcggc agtgtaggcg ccctcgcggc
     6661 atcgttcgcg gcgtcgttag gcaccatggt ggctaaactg aaccgcgcac gtccggccga
     6721 aacacgcctc acggagattg gtacgcgctt ccgcgagttg gcgcaagccg accgggatgc
     6781 ctacgctcga gttctcaagg caaggaagct tccgcctaac catcctgacc gagcggtgca
     6841 aatagcctcc ggtttattgg acgccatcga aacgccgatg gaaattgtga aactctgttg
     6901 cgaggtgatc ccgctgctgc gcggtctgtt ggcgcaggca aaaccggagc ttcagcctga
     6961 cttgaagatg ggaattgaac tggcagatgc cgcaatcaat ggctgtgtgg cgatggtcga
     7021 agaaaacatg aaagttcaac caaatcagct acttgttgca tccattcggg aacggtttgc
     7081 cgtagcggaa caaatgcttg tggatgcgaa atcgctatgc tacactccgc ccttcgattc
     7141 gtggtcccaa aacatgttga atatcctgaa acttcgctga aagagagtcg aaggtagctg
     7201 acgatggaaa ttaaggtctt caataacaac gttgaaaaag ccctgaaggt cgccaagaag
     7261 aagctggcgg gtgaaggatt gttccgcgaa ctgaagcgcc gccggtacta tgagaagccg
     7321 agtgtccgca agaaggcgaa agagcgagag gctcaacgcc gccgccagaa gtggcttgca
     7381 aagagacgtc ccgaatagac gccaggcgtt tttccttccg ccagtcatct agaccgtccc
     7441 aatttaatcc ctctttccgg cacctccatg caggcgcacg agattcatgc cgtcatccga
     7501 acggtcaagc gggagattgc ccgctggcct gacccggttg tcggcgtcgt ggccaaaaaa
     7561 tccggccgcg atccctttct ggtgctgatt tcctgcctcc tcagtcttcg aaccaaagac
     7621 aagaccaccg ctgaagccag tgcgcggctc tttgccttgg cctcaacacc ggcaacgatg
     7681 cagcagctgt cccagtcgac ggttgagtcc gccatctatc ccgtgggttt ttaccgcacc
     7741 aaagccaagc agattcagca gatttgcagg cagctgcttg atcgatacca cgggcgagtc
     7801 ccggatcaga ttgaagcgtt actcacgttg ccgggcgtcg gtcgaaagac cgccaacctg
     7861 gtggtgacag tcgggtatga gaaaccaggc atttgcgtcg acattcatgt gcatcggatc
     7921 agcaaccggt ggggctacgt gaaaaccaaa acgcctgatg aaacggaaaa ggccttgcgc
     7981 gggaaattgc cacgcaagta ttggatcacc ttcaacgatc tgctcgtgcc gttcgggcag
     8041 aacctttgcc agcctgtgtc tccgttctgc agccggtgca agattgcgga gtattgcgat
     8101 cgagtcgggg tgacaaaaag ccgttaatgc agcgtgacca gtcccggcat cagtcctgtc
     8161 cggaattggc ggcgtcatcc gttgatcaga tgaagagttt ggtttccgcc tgcgcggtca
     8221 aagagagaat cgcgggaagg ccgagcactt cgtccacgtt gcgttcgacc gcacccgctt
     8281 cgacgcccat atattcgagc cccgcgctac aggcgatgag acgaaattgc ccgacaagac
     8341 gggcttcatg aaacatctcc gaaatccggg gaaccttttt ttccttcaag agtcgagcga
     8401 cctcttcggc cgaggcggca tattccggag gaaagtcaat gtggtcgatc ttgccctcag
     8461 ccagcttctt gatggtccag aacaagagaa ccacgatgac atccttgccc atagccgaag
     8521 ccgtgaggcc gagcgtcgcg acctgatgta gcttgtcgta cgtagcgtta tgggcgaaga
     8581 gaacaaactt cggcttatcg gccatgggga ctatttgacc ttctgtctgg ttttgacact
     8641 gttgataaag tcgctgatgg ccgcatctac ctcagccgcg gtcatggcgc gatcgtgcat
     8701 ttcgctctca tcgagcaggt aacgctctcc ctgtttttcc tgccgtacga ccacagaatt
     8761 ttccggcgtg acctccacgc gcatgaacca ctctttgttg ccctgggtga taacgacttc
     8821 tttgccgagt ccgatcttgc tgatgtcgat ctgtagttct gggggtgcag cggaatcggc
     8881 agcctgcgct ccttggtcga acacctcaac ggtattcagc accagaatca ggccaaggac
     8941 ggccaggcgg caagccgagg agcggatggt ccttagcacg aagctgctgg atcgcggcgg
     9001 cagcatggtg cggaattata gctggcagag cagggaacgt aaacccgctg ggcgtcggca
     9061 ccctttccgc cgcgtaaagg cccgtgctag gatgcgccgg tgatgagcga catgttggcg
     9121 cagatcgaat cctacgtgcc ggcgagcgtg ttgatttggt ttgccgtctc gtccgttgtc
     9181 atgttcgtgg gaaccctgat cgcgattcct gtcattctga tgcggttgcc ggcggactat
     9241 ttcgataccc gcattcctcg cccctggatg gagaaccatc atccggtgtt gcggctgctg
     9301 gggcatgtcg tgaaaaatgt cgtcggggcg atttttctgt tcgcgggatt cctcatgctc
     9361 ttcttgcccg gacagggcgt gctgaccatg ttgatcggcc tgtcattgat cgagtttccc
     9421 ggcaagcggc gtgtggaagc caaaatcgtc ggacaatcta ccgttctcag cacgatcaac
     9481 gcgatgcgag ccaagttcga caaaccgccg ctgatcattg ctcccgagtg acagccgtcg
     9541 acgtagacat ccgtcgcgcc agttatccat aacccgtgtg cctattcctc catcatgccc
     9601 actctctatc tgattgacgg cagtgcctat atctatcggg cgttctttgc ccttccgccc
     9661 ttgagcaatt ccaagggctt gcagaccaat gcggtctatg gcttcaccac gatgttgatg
     9721 aaagtgctgc gtgaccatca tcccgattat gtcgccgtcg tcttcgatga aaaaggcccg
     9781 actcaccggc atgaggcctt taaagaatac aaggcgcaac ggccgcccat gcctcagggg
     9841 atgagcgcgc aggtcccgta tattcatcgc gtggtggaag cgctgtctct gccggtgatt
     9901 cggcaggccg ggtatgaggc ggacgacctg atcggcaccc tggcacgaaa gggggaaggc
     9961 gaaggcctcg atgtcgtgat cgtcaccagc gacaaggata tgtttcagct gctgactccc
    10021 aaaacgcgca tttacgatcc cgtgaaagac aagtggttcg gcgaggcgga ttcacaggtg
    10081 cggttcggcg tggagccggc gcgtgtcgtc gaaattatgg gtctcatggg ggataccagc
    10141 gacaatattc ccggtgtcaa agggatcggc gagaaaaccg ccgtgaaatt gatcacccaa
    10201 ttcggcacga tcgaggagct gttgcgccgc gtcgaagaag tgactccggc caaaacgaag
    10261 aatctgttgc tggaacaggg tgagagcgcc cgcatgagca ggcagctggc gaccatccag
    10321 gtggattgtc ccatcgaatt tgcccccgct cattttcagg cgagagcgcc gcagactgaa
    10381 gtgctggtga gcctgctgcg cgaactggaa ttcatgacgt tggccaaggc ttttcagggc
    10441 gacactcctg agcagaaccg gttaggggct gaggttcagc gcatacacga tactgccgga
    10501 gcggaagatt ttttgaaacg gcgacaaccg gacaccatga tggggctggc ttgtgtattg
    10561 agtgatgaag ccggcgtgcg agccgacatt caaggctgtg ccttcggctg gccggacggg
    10621 actgtcgcgt tcgtacaagg ggaggcgcaa gactggccgc agcccctcac cgcgtatgtg
    10681 cgggacggga gcaggccgaa ggcggtgcag gatctcaaac cgactctgtt agcgctccag
    10741 cggcagggga tcgacatgcc aggtccctac tttgacacga tggttgcaga ttatttgctc
    10801 aatcccaatc gacgggcgca taccttggaa gcgatcgcca tggacctact gagttatcag
    10861 ctcggcacgg gcgaacgcga ggaagggggc aaggaaccgc agtctctgtt tgatgtcgat
    10921 gaacgtgtgg ttcgtcgaac cggcgaggcg gcggcggtca cggccaaagt tgcgcccatg
    10981 ttgcgcgatc ggctgaaaga gcagggcagt ctgtcgcttt ttgaacaagt ggaaatgcca
    11041 ctggtgccgg tgttagccga catcgagcgc aacgggtttt tgctcgatgt cgaggggctg
    11101 cgcaccttga gcaaggagtt ggagcgggaa ctcgagcaga tggtcgggac catttatcgg
    11161 ttgggcggcg gcgaattcaa tatcggctcg ccgaagcagt tggccacggt gctgttcgaa
    11221 acgctgggcc tgaagccgct acggaaaacg aagacggggt tttctaccga tgaagacacg
    11281 ctcacgcaac tcgcgaatca gcacgagctt cccgcgcaaa ttctcagcta tcgcacgctc
    11341 accaaactca aatcgaccta tgtcgatgca ttgccgcagc tggtcaatcc tgatacgaag
    11401 cggcttcata cgtcgctcaa tcagacggtc gccgctacgg gacgactctc gtcgaccgat
    11461 cccaatctgc aaaacattcc ggtgaaaggc gactacggcc tgcggatccg tgaggccttt
    11521 attgcgccgc ccggccatca cctgctctgt gccgactata gtcaggtcga gccgcgcatt
    11581 ctggcccacc tctcccagga tcctcgatta ttggaagtgt tcgagaaggg ggaagacatt
    11641 cacatggcga cagccatgga aattttcaac ctgcctgccg gcgacgtcac gcgcgaaatg
    11701 cggcgcgcgg cgaaaagcgt cgtgttcggg atcgtctatg gcatcagtcc gttcggcctc
    11761 gcatcgaaca tcggtgtgcc acaagctgag gccaaaaaat acatcgaaac cttctttgaa
    11821 aagtttgcag cggtgcgtgc tctgatggac cacaacatca acgatgggaa aaccaagggc
    11881 tacacgacca ccattctggg ccgtcgtcgt cccattcccg aattgcagag cggtgatcca
    11941 tctcaacgcg gggtgggcga gcgcatggcg gtcaatagtc cgattcaagg ctcggcggcg
    12001 gatctgatta agctggccat gatcaaggtg catcggcgct tgcgagacga actgccgcgc
    12061 tgcaaaatga tcctccaggt tcatgacgaa ctgatcttcg aagtgccgga tcaggagctg
    12121 gagcaggcga agcaactcgt caaagcggag atggaagcga ccggtgacgc gttggggtta
    12181 tcggtgccgc tcaaagtgga tgtcggagtt gggtgtaact ggcgcgccgc ccatccgtag
    12241 ccggatgttg aaacaggttg ccagcggcct tctcagtcgc acggcttcct gcgacatctc
    12301 ccaggctgta tgactcagtc gccgcactcc atgcggcctt gccggacagc ctgtttgaac
    12361 atcctgaaca aagcagctgt tgtgtagagc gtaagttggt tcagttcagc ccatgtcgcc
    12421 gcgaaagcgt agattgacca tcccagagcc ggagtttcag gccttggttc agcaggcgct
    12481 ggacggcctt cctgacgaat acgccaagcg cattaccaac gtcgccgtgg tggtagagga
    12541 tgagccttcc cccgaggtcc tcgccgatct tgacatggac gaggacgagg atctgctcgg
    12601 cctctatcaa ggccttccca tcgataaaga gtctttcttt caggcgggcg ggcaactgcc
    12661 ggccaaaatc tccatctatc gcggaccgat cctcagactg tgtcgcacga aacaggaagt
    12721 ggtgcaggaa gtgcgtgata cggtcgtgca cgagatcggt catcatttcg ggtttgacga
    12781 cgacgagatg ccatattagc cggatactga aacaggctgc cagcggcgtt ctctgtcacg
    12841 actctctgcg atgtccacag ccgcatgtct cgggagacat attcacgaaa tgacagctgc
    12901 taagaccttc cgattggctg cagtcgcggc gctgacgaat gccaatcaat tgtgtgccga
    12961 agcgagactt ctggccgaaa acgaacataa ttcaagggcg gcagccctag cggttatagg
    13021 tttggaagaa tttgctaagg cggtggcctg tacggtcgcg gcaatctttc ctgagaagag
    13081 cagtgatcta gggaaccgtc ttaatgccca taatgtgaag caatggattt accagacgtt
    13141 tgaaggcata caaattcagg ttcaagattg gctcaacgta gttccttacg aatcgggcgc
    13201 cggttctccc atagagccag aaacaattct tttggagact tttagaacgc tttcgaaaag
    13261 cagatggggc agtgtcgttc ccactaagaa ttctgccgat tccgctgcaa agcaggatca
    13321 aaagtattta aacgatccga gaatgcatgc tcgtcccacc gagatcatga caaccccatt
    13381 cataaagaac gtcgcatttt atgtagatgt taagaaggga gaggttctcc tgcctaacag
    13441 ggtcgataga tacgccaatt atgagattca cggtcttact tggtcattag aacacagttc
    13501 tcctctgaag cagatccttt cagatgatca taaatgggag gcctttgcag atgctgttcg
    13561 gcgaacacca ggagctggcc tgagcataga agcagaggta ctgacgccaa agaaaacggc
    13621 gattaagcag ctccggcgat tgcccgagac ggcgacatgg gatcaaatca agaaggaaat
    13681 tgagaggggc gcccaggagg ccacggaaga acgaaagctg acttcgtagc gggatgtgtt
    13741 aggtcacgct tacgagtaca gccgcccgac gatctgattg aagttgaaga gaatcgcgtt
    13801 tgcgcgcgtg taggcggcgt ggccgtagta atggtcgcgg acgttggttg agctcgtgca
    13861 gtctttgtaa tcgacgagca ggcactgtcc ttcgctggga aagcgggtag cgcggcgcgc
    13921 gcattccacc caacgttcaa acccatcgta aggttcgagc aattcccaca cggctttatt
    13981 ggctgctttg gcactctcag cgggtagggc atcgctgccg gccacagcca attcctgcac
    14041 gtagtcgccg ccccacgcaa tcggcatttc gacggagatc tgcgggagct ccattttgga
    14101 gagccaggtc tttccatcgg tgcgcagatt gcggtgattg acgatatgta gaagcttgcc
    14161 gatgccggag gggtcccatc cgtaccgcac tggtgtgccg aaggtgacga tgtcgagggc
    14221 cgcgccgttg aggagggagc ccgaagtcaa caaaggatcg atgcgctgaa tggcctgcac
    14281 atccgaatgc tgcgggttcg ccgccaggag cagatcgaaa aacgctttcc ggccggtaat
    14341 gggcgaaggg cagagtagat tcgcggcgag cgcgagcaca agtccggatt gcccatgggc
    14401 ttgaatcaga atgcgatccc cggttcccag atggtgttcg gtcactaagg cccgcagacg
    14461 atccaagagc cggcaggccg ccagggcacg gccgagatgg tgatgctcgc tggaccagag
    14521 ttcgcgtacg cagacgatgg gtttggacac gtgctgattg agggccttgc ggcaccgttc
    14581 cacgatcggt gcagtgaaat tgcctgcgtc gccaatctgg ctatcgagca ggcttttggt
    14641 cgcctcgtca ttggcgagcg gcggtttcat gccgcctggc agcggtgtga tgccgttggt
    14701 gccttctcgc ataaacgaca ggagcgaatc caatccggag atgccgcgtg aatatccgcg
    14761 tttgaggccg cccacttcgt cgagtcgtcc taaaccgaag atgtcggtgc cgggaatagc
    14821 cccatgcaga aagacgatta ctcgcactcc ggcctgcgac agcttctggc cggcctcgcc
    14881 catagcggct tgccaggcgg gcgaatccat gtcaggcggc ggcgtccagt ccgcataggt
    14941 gagacgatcg ccaggatttt tcctggagag ttcgtcatgc tggaagttgt tttcgatcgg
    15001 catgggaaga ttgtcttacc cgaaacgcag tccgaagttc aatggagggg gatgttcgga
    15061 aggtggggac gctcagtgac gggcggacga ttcggccgca ggtgatgtat ggagggtggc
    15121 tttcggcatg acggccaccg ccgtacacgt ctttgcctcg tcgtcgatgc ggcgatcgac
    15181 gatcgtcacg ccctgcagat attcttgaac gatttcttcg cgaaccactt cgatatcctg
    15241 ctctggttca cgaccggtgc gttccctcag gcggtcggtg gcatgctcct tgacctggac
    15301 ccgaatttgt ttggcgatgt cagcccgagc ggccaattcg gatactcgct gacacaccag
    15361 ttttccttta ctcaaatcgc cctggccctg tccgatgaaa aattggtcgg gatggtagga
    15421 ggacgaaggg tcctgctgcg gccggtctct ggttgttggt gcaatagtct gttctcgtgc
    15481 gcgaagctgc tgaaagtgtt ggtcggcatg cgtccgaacg tcttggggtg tgagttcccc
    15541 tgccatggtg gctgtggcca caagcagagt cccggccatc cctactgcca tgaggatgtg
    15601 actggatgtc agtggcatgg ctatttgtcc ccttgattgg tggcggaacc gcgttccgca
    15661 gtggactcgg aaggcgaaag cggtttcgtt tggtggatga ccggggggcg ccctcctcga
    15721 atgccaccgt cagccgatcc tggtatcgac gccgaggggg gactgcctcc ggcgcgatag
    15781 gtatgcaaag tcggatgact tgcctgacta ttcggcgccg ggatctgtcg ataggtcggc
    15841 atcatgttgc ggtccgggac ggacggtgag gtgccgggtc ggggatgagc ctggataatc
    15901 gtcgtactgt tgccggattg tggcggttgc ccggatggat tgggcaacaa cggattgagt
    15961 tggtagacgc ttgagagctg cttggaatca gtgggtggag gtgtgcctgg gggagccggt
    16021 tccttcggca cgacatagta ccccggcaaa aatggcacgg tatgcggcac gggtgactgt
    16081 cgagggtgag ggggtgccgg ggggagcttg gctcctacgg tctgttgtgc aatggcgagg
    16141 tgaggattag tcgggttcaa ccgccctgcg atgccaagca gcgcttggac ctgagccacg
    16201 cctgctgaag ggtaggggtg cgcgaagggg gcaatcaaca gccagtcggt ccaggcctgc
    16261 gccaccatgg catccgattc ggcgtgattg agcagatccg tacgctgctg gttgagtttt
    16321 ctgacctgct caggtgaatt cgcgtgggcg agcgcctgat tggcgtcttc gagttgttta
    16381 tgcaggctct cgacatcttc cttgagggcg agtaattcct gccgcacgtc ctcgttctgc
    16441 ttcatcgcga gaatggcctg cgccgcctct tcgctgtcta cctgggcttt gagggtgacg
    16501 cggatcacca cgacatctcc atcaagagcg gtgtccacct gttgatccag caccaggacc
    16561 atcccggctg tgtagctgcg aagttcatct tgagtcacgt cgagattctg caccacggtg
    16621 acactttcca gatatgacgc gacctgttcc agcgcctgtt gtttcgcctg ctccgcggcg
    16681 agccggatcg catcgaccct ggtttcccag tctgtcatgc gatgctgtcc tgtggccgtc
    16741 accacgcgaa cgtcggcaag acttgggcta ggagaggcga agaagaggag aaagcctgct
    16801 gtgaaaagag cgacgagcgg catgaggcga cgcttccctg aacactcgac ggtcaggcag
    16861 aagaaatcac tggaagaacg gttgccgggc attgtggtgc accgctgtaa aatgggtgtt
    16921 cggagggttg atcgcactgg cctcttcccg attcgaccag gataccatcg aacccgctca
    16981 ggcgctatga gagccgaggt tcgtgccttg ccttcccgga aaacagcgtg ctaaggtact
    17041 ttttcttcgc ttcataaatc gatcgtctgg tgaggcaatc tcatgagttt tatccgcaat
    17101 atttccaccg tcccggttgc gttttgcctg gcggttgttc tgagtatgac cgtcgtggcc
    17161 tcgtcctctt cctcggtggc cttggctgca cggggtgcag gagacattcc gccttcggtc
    17221 cccgcaggga tgacagaaca tgtcatcctg tttgtcctgg aagggtttgg ccaggaatca
    17281 ttgaagagcg gtgtgatgcc ggtcttgtct tctctcgtga aggagggggc cgttacctgg
    17341 tcggcgacgg cggttgcgcc tgcgcgccgg ttaccaacca tggcatcctt ggtgacgggg
    17401 atgccggtcg ccaaacatgg catcacctgg aacgtctttg aattcagccg gggatacccg
    17461 cgcgctccga cggtgtttga ttatctcgat ttgagcggcg gccgggacag tgccattttc
    17521 tacatggacg aatctctgta tcagctcgcc aaaccggaac cctatacgga ctatcagatg
    17581 tgcgggccac tcagagccga gtgcaatccc gaccggttgg tggggtatgt gcgtgactac
    17641 ttcaagaagg ccacaagcgg ttccggatat ggccatgcca ttccgtcctt gccgcacctg
    17701 ctggtcgtgc atctgccggc tcccggtcgt gtcggcgaag cgcagggctg gaaatcagcc
    17761 gcatacaaag acgcattgaa agctgtcgac aaggcgatgg gcacggtgtt ggatctctac
    17821 cgtgaactcg gcttgatgaa acggacgacg gtctttgcga cgtcgctgag cgcctttgga
    17881 gagacgcaat tttcatccgg tgacatgtcc gccgatcaag caggcgccgt cccggtcgtg
    17941 ccctggattg cctcaggcgt cggcatcaag gccggttacg cgattcgtca gccagtgtcg
    18001 attatcgata cgggcgcgac tgtcatgcgc gcgcttggac tgacgaccta caccgaatgg
    18061 gagagtcacc cggtcgagga aatttttaag accgcgttca cggttgctcc tgtcaatcca
    18121 ctccttcaat agaggaccaa tggatatctt gtcgcacaga ttgtttacgg ggcggcagac
    18181 gttgatccgg atcgtcgcat tgtcatgcgc tgtgttcgct ggacatgcgg agcggctcct
    18241 ggcagccggt ccgccgcctg cctataccaa ggaacatacg attacaatcg atccgactcc
    18301 gttggtgccg caatcctggt ggcaggtgcc cggcatcaca cccccgctct gggtattgga
    18361 tccagaaacg tcggatgcgt accggacgac cgagactcgc gaattgcacc tcaagccggg
    18421 acaatataag ttcatcagtt ttaccttcga ctttcccttc acggtgagtt tggacgggaa
    18481 actggaatac tccaagtcac tcgatcaatg tgtggagggc cgcgggactc agaccctggt
    18541 ggtacggtgc aagcgcacct atcctcatgg cggtcaacgt gatgcctatt atgggaatag
    18601 tgaggtgggt gatggcacag gcactcgatg atctactgga ttccctcgaa gatccggatg
    18661 atgcaactcg tgaagaagcg gccaaggcct tggcgcagtt ggcgaacccg accacgctgg
    18721 acgcgctgat cggcgcctgc ggcgacgagt attggtctgt gcgtacgcgc gccggctggg
    18781 gtgtcgccaa aatcggcggc ccgaaggcga tcgaagcgct gattgcactc ttcaacgatc
    18841 ccatcatgga agttcgcaac gaagcggtcg cggccgtggt gtccctgggc gtggggcacc
    18901 tcgatcggct tcttgtggcg atgaaggacg aacggtggcg tgtcagggaa catgcggcga
    18961 aagcctgtgg ggaccttcgc gatgcacgcg cggttgatgc cttgatcttt gcgtgtcggg
    19021 atcgcgacgg tgctgtgaaa agcgcggcgg cggaagcgtt gggaaaaatt ggcgacgcca
    19081 aagccattcc tgccttgatc aagttgttcc gggattcctc gaaaattgtg cgtgagaccg
    19141 ccggcatcgc gctggtcgca attggacagc catccgtcga cctgctgctt gaaacgatga
    19201 aggacaagga ttttgtggtg cgttgccatg cagcccgggc attgggtggg atgacgacgg
    19261 actatcaaat cggccggagt tgggtgcgtg aaccgcgcgt tgttgatgcg ctgatcgaag
    19321 ccctgaaaga tccggaccgg gccgtgcgcg aagatgccac gattgccttg ggcatgatcg
    19381 gtgacccccg cgcgatcgat gggttgctcg aagccatgaa agatggcgcc gtgaagcgtc
    19441 atgccatcgc gtcgctcggc atgatcggtg acccgcgggc tcttccggcg gtgctggcgg
    19501 cgctcaaggg caaaggtgtt cgtcaggatg ggacgcccac cccggggtgt atcgtcagtg
    19561 aagacgcgtt tattaaggaa gcagctgcga ccgcacttgg acatttccgc gatccccgtg
    19621 tgatccccga tctcatcatg ctgttgaagg atggcgtgtt gcgcgaaaag gctgccgcag
    19681 cgttggtgtt gatcggcgat tcggccatcg agccgctgat ttcattcctg tacgatccga
    19741 aggcctccga agttgaagcc gaaggcgagc gggtgctgtc ttacgcgtcg gtgcggttga
    19801 ccgcgaagga ttccttgcgg ttgctggtcg tggaaacgct ggagcacctg ggatggacac
    19861 ctccggatga agaaacctcg gtggattcca gccaggccga caatcttcgt gtcgatcggc
    19921 cgttgggaga tatcggtcgc ttcggtccga gcggagattt tgcgaaagga tcggtgcggt
    19981 aattctcggc gttctctcgc ggggtgcctg gcctgttgag agcttccggc gtccccgcgt
    20041 ctcttcctct ccgtttcgac cagcgtgcgg gatggtgcga tgtcaggtcg tagggccaac
    20101 ccgcgttgac ccctaaaaaa atgctgtgtt aaggtcgatg gcctcccaga ggccgaggta
    20161 ccatggccga caccgtcagt gaacagatcg cagccctgtc ggatgaggat tgggccgttc
    20221 gcgaggaagc ggcgaccctg ctggggagct taaacgatgc gcgggccgta ctgcctttga
    20281 ctcatgcgct gcgcgatacc gatcgtgctg tccgcgaagc ggcagtgggt gccctctcat
    20341 cactcggatc cgtttctgtt ccggccttgg caggttgttt ggctgatccg gccttgcagg
    20401 tgcaagaagc ggcctcggcc attctggctt cactggccga tgcgcgcgtc ctggcgcctc
    20461 tcatgcaggc cttgggcagt cgtgattgga tcgtgcgcat gcacgccgca aagggcctgg
    20521 ggcggatcgg cgatccggaa gcagtgtccg cgttgatgcc gctgctgcag gacaaggtca
    20581 aggctgttcg cgaggaagca tccactgcgc tggcggccat cggcgtggcc gcgatggcgg
    20641 gattgatcga agccctgcag catgatgatt ggctggttcg ccttcatgcg gtggaggcgt
    20701 tgggaaagct caagtcgccg gactccgtcg agcccttgct gagggcctta ttcaatgaaa
    20761 gggactcagc gattcgtgaa gatgtggtcc gggcgctggg tgcgatacga gacgggcgtg
    20821 cggtagatta tttggtaacg gtgatgaagg agccgggatt acggctattg gccgtcgagg
    20881 cccttggcca tatcggcgac cgccgggtcg tgccgatttt gcggcgggtt gtcgagggcg
    20941 tcccgctggg tgagccgagg gattcggcca caccctgtgc cgacggatgg acggatgaga
    21001 tggcgaccat gggaatggcg gcccgtgcat tagggatgat tgccgatgcc gtggcgattc
    21061 catcactcat cgtagccttg cggaatacca tcaccaggtc ggaagccgcg gcggccctga
    21121 cgaaattcgg tccggcggtg attccgtctc tcttaccgat gttggccaaa gagcaggatg
    21181 agaatgtccg gtatcacgtt cgggaaacac ttacggcggt cgggtggcgc gccgggcgag
    21241 tctgaacgta acgctgtgcg gatcgtgtga gaacgctatt tcggaagcag gcttcatcgt
    21301 aagcaatcag taaaacatcg gctacgcaac tttttcacga tgtccaaaga gtccatcgat
    21361 accttagttt ccgagttgac gcatgaggag gagtggcggc gtatgcgagc caccgcggcg
    21421 tgcctagccg gtggtccacg ggccgtccag gccttgacgc acgcgttgca gtcgggcgac
    21481 gtccctcttc gtgttgaagc ggccgcgatg ttgtcccgca tcaaagatcc cgctgcgggt
    21541 gttgcgctgg tcaccttgat tcgggatcct gaagcgacgg tacggcaggc ggcatttgcc
    21601 gcgcttgaac agatggccgg taatctggac gacgagactg cggcgggctt agtgcggaac
    21661 cttcacgagt caccggatga ggaagtccgt caccgtgttc ggcagctctt gggcgtgatt
    21721 cccaatgcga tcacgccgtt gtgtgagatg ttgcgccatc cggatgcgga ggctcagatg
    21781 acggcggcga cgattctcga gcatctgctc gatccgcgtt cggccgacgg attgatcgat
    21841 gccatggctt cgccggcggt ccgcgaaatc gtcgtgcgga cgttgaagaa gctgagcgcg
    21901 gtccgggaac ggatcgatgc gacgtttaat gcgttgcgtg acgtcgaagg cgcgagcgaa
    21961 cgcgaggaag cccgcatggc gacggtgatg gatcttctgg ggatcggccg gccgtcggtt
    22021 gagattctga tcgaatatct tgaggacgac gattggctca tccgtgaagc tgctgccgat
    22081 ttgctcggca aaatcggcga tgtgcgtgcg gtcgaaccgt tgatgaaacg gctccagaag
    22141 gataaggata ccggtgtgaa ggagtatgcc gtgaagtcgt tggggctgat tggcgacccg
    22201 cggccggccc aattgtatat cgaagcgatc ccgatccggc ccttgcgcgt gatggccatc
    22261 gaggcgctgg ccaaaatcaa agatgtcgag gtcttgcgtc cgtataacga gctgttcaac
    22321 cggttgcgaa gcgatcggga cggtatcgta tcgtacagcg ccggcctcat tgcggataaa
    22381 cttgcggcac tcgagggcga acagccggtc gggcaggagg aatcggacga tcatgagtga
    22441 tgccgagcga attgcacaat tgatagcggc gctgcgcgac gataatgagg cgttgcgcga
    22501 ccatgcgatg gcgagcctcg gacagatggg aattgaagcc gttccccaat tgatcggcct
    22561 gatggccgac gaggatgtgg tcattcgcga ggcggccgcg acggcggtgg tgcgtatagg
    22621 gcccattgcg ttcgatcagc tgctggaagc cttacgagac gatgaatggg cgatccgcga
    22681 gcaggccgca aatgtactcg gccggtttcg cgatccccgc gccattgatc ccctcatggt
    22741 ggcgctcaaa gacaaagacg gggctgtcag gactgcggcg gtctgggcgt tggagcggat
    22801 cggcgactcg cgggccacgc ccgggttgat tgaagccctg ggcgatggca cggtgcgcga
    22861 ggatgtcgct cgggtgttga agaaaatcgg cgatactcga gcggttgatg cgttgatcgg
    22921 gggtctcttg ggccccaatt ggatggttcg acgccatgcg gcggaagcgc tcggaaaaat
    22981 cggtgatccg cgcagcgccg acgcgttgat tcaatcgctg caggatgagg actggctcgt
    23041 ccgccggaac gcggctgaat ccttggcgcg cctcggggcg aagcatgcca tcgagccgct
    23101 gcttcctctc ctggaagatg aaaatacgat ggtgcaggag accgtcgaag gtgtactcgc
    23161 gagtttggga tggaaacagg cgacctcgtc ataacccgat aaaggaactc tactatggca
    23221 gaagaagcac cggtaaaact cattcagatc ggcccgaagg gcggacccaa gaaggacggc
    23281 ttcaacctgg tgacggagcg cgtcgtggcc gtcaatccgg aagcgaggca gctggaagtt
    23341 gagctgttgg cctatgacgg aaagaccgtc gtgcttgatg tcggagaaga agcccttgag
    23401 gatttcctca agatcaagcc gggtgacggc gccacgattc gtgttgtcga agaaggcggc
    23461 aagcgagtgg cgaagagctt ccggattcgc gcgaaagatc cgaatgccgc caaagccgac
    23521 gcgatgctga tcgacttgaa agattcgcac tggctcaatc gtaaatatgc agcggaagtc
    23581 ctgggtgatt tgaaagatcc gcgggcggtg gtgcctctgg ttgaggcgct caccgatgag
    23641 gttggcgatg tgcggcagcg ggcctatgat tcgttgatta agatcggcgg gtcggccgtt
    23701 ccctcgcttg tcccgttgct ggcctccgaa gaagacgatg tgcgtcagtc ggcgacggaa
    23761 atcatcagga agatcggcaa gccggccgtc gaacccctcg ccacggcgct ggcggaggct
    23821 gacgaccggt tgaagaccaa gatcatgaag gtattggacc ggatgggtta taagcccaag
    23881 gcgaaagaag gggctcagcc tgaaccggcg aagttgctca gttagcgaga cccgtccggc
    23941 cgccggttag gcggccggat tcttggttgg acgaccgact gatacgtggc ggaagccgaa
    24001 ggggacgacc cggtccgact cgtaggtgtt gcgcaggtcc agcaacagtg gttcccgcat
    24061 ggctttcttg agccgttcga aatcgagatt tcggaattgg ttccactcag tcatgataat
    24121 gaggccgtcg gccccttccg cgacttcgta ggtgtcctgg caagggacca tgccggggag
    24181 cagtttcatc gattcttcca tcgacgcggg atcgtacgcg cggatctttg ccccttcctt
    24241 catcagctcg ctcaggatgg ttaacgatgg cgcttcgcgc atatcgttcg tgttgggttt
    24301 gaacgaaagc cccaacacgc cgagggtttt cccctttact cctccgcagg catccttcac
    24361 tttctgaacc attcgcaggt gctgttcgta gttcactttc gctgccgcgc ctgcaatctg
    24421 gaacggatac cctacacgct caccggtctg gaccagcgcc gcgaggtcct tgggaaagca
    24481 ggatccgccg aagccgggcc cggcatgcag aaatttgttg ccgatccggt tgtcgagccc
    24541 catgcccttg gagaccagct ggacgtccgc tcccaccttt tcgcacacgg tcgcgatctc
    24601 gttgataaac gaaattttga cggccagaaa tgcgttggag gcatacttga tcatctcagc
    24661 agttggaatg tccgtgacca cgatgggcgt ctcgagcaga tagagggggc ggtagaggtc
    24721 cttcatgatc gcgacggcct gctcgctgtc tgcgccgatg accacgcggt tcggccgcat
    24781 aaagtcttca atggcggagc cttcccgcag aaactccgga ttggagacga tatcaaaccg
    24841 gaatcgaccg gtttggttgg ccttaatcac ttcgcgcagc ttttcgccgg taccgaccgg
    24901 cacggtggac ttggtgacga tgaccttata cccggtcatg ttcttcgcaa tcccgcgtcc
    24961 cacctcttcc acgtacgaca agtcggctga cccatcagat ttgggagggg ttccgacagc
    25021 aatgaagatc acaagggctt tatcgacggc tttggcgaca tcagtcgtga aatggagccg
    25081 gtcttctttg atgcctttgg cgacgagttc cgtgatgccg ggctcgaaaa atggcacttc
    25141 acccttttcc agtttggcaa tccggcgcgc gtccgtatcc atacaggtga cgttcacgcc
    25201 gaattctgca aagcaggccc cggtgaccaa gccgacatag cccgttccaa tcacgctgat
    25261 atgcatggat gcatctcctc ttaaagaaaa gctgcgaatc gtgggtgagc gtttcgtgta
    25321 gagtgcgtag tatagcaacg catgccagac cgagcaatca tctcggaggt ttttgcagtc
    25381 cgtgccggat agcgcatggc aggatgaatt gcagattgtg gcgtacttca gtagaattcg
    25441 gcctcttcgc aggagggatg cgcatggtgg ttgcaggcgg gcccatccaa cgaccgttgg
    25501 ccatgatgat gcgtcccatt acgaagaccg tgcgacccga tgattcgtta ttggtggtag
    25561 cgcagcaatt acgcgatgcc cgggtcgggg ccatgctcgt cgctgaccat ggcgactatg
    25621 tgggcattgt cagtgaagcc gatctcgttc gcaaggcgat ggccagcggg gccgcgtcag
    25681 accaggtcac ggttcgctcc gtcatgagtg cccccctcat gacgatcgat atcgcccaat
    25741 ccgcgcatga ggcgagcgat gtgatggctg aacgaggaat ccggcatctg gtgattaccg
    25801 atgaagggcg tgtggtgggg atgatctctg ttcgcgatct gcttcgatac ttcaagaatt
    25861 ggggtacttt gtagcatggt gtgctcgccc gcccgctgtt gtcgcttccc ctcacggtgt
    25921 ctttcggtct ttggtcgatg atggcacaaa gacctgccgt tgttcccatt ccccgtctct
    25981 tcttgctgtt caccgcgctc gtgaccggcg cgatcgtcat ggcgctcgaa attctgggca
    26041 gccggctgct ggctcctgtc ttcggaaatt ccctctttgt gtggggcgcc ttgatcggga
    26101 tcattctcgc ggccatgagc tccggctatg cgttcggcgg ttgggcttcc gaccggtatc
    26161 gtgttgcggc ggtgttggcg tggctgctgc tcggatccgg cgcgtggacg ttgctgatgt
    26221 cctggatggg gcagggcgcc attttccagg ttgccaaact cgtcgaggat ccgcgatggg
    26281 gccccagcct tgccgcctgt gtcttgctgg cccctccggc attcggcctg agcggtgtga
    26341 tgcccgcatt gctccgatta gccgttgtcg atatgggata tctggggcga cataccggca
    26401 gcatgattgc gttatctacc gtcggcagtc tggcgggaac gtgggggacg gcgttctttc
    26461 tcctttcgtg gttgggcacg cagaccctcg tagcgacgct gggggtaatc caattgctct
    26521 tgggattact ctggttgcaa caaggaagcg ggagagtcac gaagttaacc ggggtggtga
    26581 tgaccggcct gctcatatcg ggttggcaac tgttcggcca ggctcctccg gtcgcaggat
    26641 tggtctatca ggaagatagc ccctatcagc aagtccgtgt ccgtgacgat gatctgtttc
    26701 gttatctcgt gctcgatcgc acgtggcatg cggtcatgtg gcgatcagac ccgaccgccc
    26761 tgtttttgcc ctatagccaa ctgatggtgg cggcggtcgc attggctcca gagccgaaac
    26821 gaggactcat tttaggacat ggcggcggct cgttggccaa gtggcttgct caagtctggc
    26881 ctgagctaga gttggatgtt gtcgaattcg atccggtggt ggtgcggatg gcggaacagt
    26941 atttcgatta tcgccctcct gccaatcacc atgtctcagt gaaagatgcg cgcgtgtttc
    27001 tgcgcgacac gaaagcgacc tatgacgtca tctgggttga cgcgtttgcc cggcatctca
    27061 ttcccttcca tttgacgacg gtcgaattct tttcggagct tcgaggacgt ctcaacccca
    27121 atggcgtgtt ggctctcaat ctggcttctt caggggaggg tggcgatctt caacgtgcga
    27181 atgccgtggt gcagacattg aaaagctcct ttccctcaat tgaatcattt ggggtaaagg
    27241 gaccgtggcg tgcgcaccag accacggcag aaaatctcat tttcttcggt ggcggcccga
    27301 tcgctacgat gtcgtatgac gagatcgtga agcgtattta catgcaggtg gaagcccgtc
    27361 gattgcccct cgaagcgata gccttgctgg cctcgcgacg tgccacgcct tggccgcccg
    27421 ggctgacact cacggacgac tacacaccgt atgacctgct gatcggctcc catgcagtcg
    27481 aaatgtcgcc agaggggaat tcatcgccgt aagtggttga aatgtagcta cgaagtgccg
    27541 atctatcctc tacatgcgac gagcatttcc tgcctaaaga ccccgtcttg accgtccaag
    27601 aactttcttg cttcctttta aatccctatg ctataaggtg accctcatca gccttttatt
    27661 taggacattt ccgagcagtg tgtgctagcc tccggggcgc ggtgtctagc agaaggttca
    27721 gatcgcggtg gtcattattc accaacctaa tcgcatctct tcttaatctc tttaaggagg
    27781 taggtcatgg gcaagacgat ggtagctgta ttctttggcc tggtcatgtt aatggctggg
    27841 gcatccggcg cgtatgcgct gcaagctggc ggtgtcgaga tcggcgatct ggataccggc
    27901 tccgtggtcg gtcagccatt taaagaattg attgtggatg cggaattgta tgccgtcgag
    27961 atcgggaact tgaaggcctg gtatccaccg gtcacggtga ttgattttaa agttcgcccc
    28021 ggccgtccgg ttgttctcaa agtgacgaat aactcctcca gcgagcatgg cttccagatg
    28081 accgatccgg tcaacgcagc atcaccgttt gtcatgaaag cggaagtggt gctgaagcct
    28141 ggcgagacca agtatatcgg tgtgcctacc agcgacatgt tcaatgccac gcagggcaac
    28201 acgctgacct atcgctgcca tctgcacccg gctcacgtcg gtggcaagct ggtgatgatt
    28261 aagtaatctg agtttgaacg gtacgagttg caacgcccca tctgcagtga tgcagatggg
    28321 gcgttgtcgt atcaagggcc tgtatcgaaa tcgttcttgc ctagacttcc tgttcctttt
    28381 gacattctgc ggcagcatcc agcggaatgt tttgaatgcc ttgcaggcgt ccttccacga
    28441 tcaacagcag aaaccgactc tccgtcggcg gcgcctctcg ccggtctgtc accacggtat
    28501 tcatgtccac gatcatttcg tcgccgtccc attgggtgtc gttcaccacc caaaaatgac
    28561 tggccgcatc aggaaattgc tttgtgatga aactttcgat gatcgtgccg atatccccta
    28621 cctccgtcat tgcgtaggaa ggcagcggtg cgagagcgag gatggcaata catgcaaggc
    28681 gcgtgaagca gttcatgtgt acctcccgtg gatagggggc caatgaatgg acgccgcggg
    28741 gccacgtagg ggcaagttgg cctgcgcatg ccacaattta cttaaagtct acagcgatcg
    28801 actgcggaaa gccaggtatg gatctgttgt tgcaccgctg gttagtggaa aaacagcgaa
    28861 ggctcccgga ggagccttcg tggtgccacg cacatgtact gaacctaatt agttacgaac
    28921 gccgctccag accttagccg gatcaatttc tttgtccgga ttcaatgact tggccttttc
    28981 caacaatacg tcagtcgtct ccggataggc tgggtcagca atgcagcagt tgtccaccgg
    29041 gcagacagcc gcacattgag gctcgtcaaa gtgcccgacg cactccgtgc aacgatcatg
    29101 ggtgatgacg tagatgttat caccgactcc ctgcccgtct ccgacgtgat tgcccttgcc
    29161 ttcagcatcg ctgcgcgttt cgaaaattgc ttcgttggga cattcgggca ggcatgcccc
    29221 gcaggaaata cactcatcgg tgatcagaag cgccatggcc tatgcctcct tcgcagttcc
    29281 tttaatgacg gataagatgt tgacaatttc gtgccgccgc gaccatagtt cgcggcgaaa
    29341 caggtccgca ttctatgctg gcgttcttcg gcaagtcaac agaatgaggc ttgggaagaa
    29401 ggcctagcac caggaaagtc atggggcttt gggcccaatg tacatgcggc tctacgcagg
    29461 tacgactaca tgaggatgca tccatgtccg acagcatttg gttatggtga cgcgcgcgag
    29521 cgggtctgaa tcggaacagc gtcgcaagaa aattgtgacg ttcgtgctct tagtgatctt
    29581 gctgatcagt gtgagcctgt ttctcggcgg tccaaaggaa tccgaactca tcattgtcga
    29641 attcccgaac gggaagacga tggagacaga ggtggccagc accccggaaa agctcctgtt
    29701 cgggttggcc ttccgggaag gattgccagc cgatacgggg atgctttata tctttgaatc
    29761 gaccggtttg caccgtgtcg cgactcgtca attccgcatt cctgttgata tgttgtggat
    29821 tgatgagagt catcatgtgg tacacattct cgagcaggtc cagccctgcc tccaggatcc
    29881 ttgcccgttc tacggtccgc ctcccgagcc ggttcgctac ttaatcgaag cagaggcggg
    29941 gtacgcaaag cgcgcaggaa ttaccatcgg tatggagctc aagttcacat tacggatgta
    30001 acagtaaggg gagccggaat cgtttatgga agggtttcag tgcgtggcca aggttgaaga
    30061 tattcctccc ggccaagtca aggtcgtcaa ggtgaatgag cgtgccattg cggtctttaa
    30121 tattgagggg cattttcacg ccatctataa ttcgtgccct catgaaggtg gtcctttaaa
    30181 taaagggcgc gtgaaggggc atgtcgtctc ctgtccctgg cacgacttgg catttgatgt
    30241 gcgaaatggg caaggcacgg acggcggggg gtattgcgtc ggaagttatg atgtgcgcgt
    30301 agaagacggg cagatattcg tcggagggcg gcgcaaggtg tagccgcacg gaatgatgat
    30361 attggagttg ttaggaagat gagtccactg agcaaagcgg tgccgacagg taccgagcag
    30421 gagccgggtg ccaaagtcgt gaaggcgcga gtgggactgc cggttcatat ccggctttgg
    30481 gaagatcgca cgcggggaga gttatgggtt ccgatctatg acgccgcagt catgcccttg
    30541 gtggaggatg attttcttcg taccgccagc aacaatgcgg tcgatcaagg gcagcgtagt
    30601 ttcgagttca agccctcggt tgccggcact catcgggtgg tatttgagaa gcggctgggg
    30661 tggaagttca cagccgaaga ccggcaaatt ttttatgtca ccgcgtccta agaagagggc
    30721 ggcgagaaaa aggccatgcc tgacattgca tgcgtgaacg gttgcttcgg tcctgtggcg
    30781 gaagccgtag tcagcatcga ggaccgggga tttcagtttg gcgacggtgt gtatgaggtc
    30841 attcgcacct atcgcgggaa accatttgcc ctcgatgagc atttggcccg ttttgagcga
    30901 agtgcgcagg cgttgcacct ctcgttgggg cttaccaaag atcagtggat ggcgctcgtt
    30961 caggaaggcc ttcggctgag ccagttccct gagaccaaaa tctatctgca ggtcacgcga
    31021 gggcaggctc cacgggatca tctctttccc gcctccaccg tgccaacgac cgtgctgact
    31081 tttcgcgaac tccatccgct ggatgcctca attcgcaagg ccggggttgg agccgtaaca
    31141 gtggatgaca ttcgctgggg acggtgcgat atcaagagcg tcaatctctt ggcgaatgtg
    31201 ctggcgcggc agcgcgcgaa ggaagccggt gtgtttgagg cgattttagt tcgagatggg
    31261 cttgtcaccg aggggtctgt cagcaatgtc atggttgtgc gaaacggtgt ggttgagact
    31321 gcgcccgaag ggcaccgcat tctctcaggg gtcacgcggg cgatggtgct ggagctggcc
    31381 aggaaggaag ggcttcccgt ggtggagaca tttgtcggtc gggaagatct cttggcggca
    31441 tccgaggtgt tcttgacggg aacgacggtg gaagtgttgc cggttgtgcg cattgacggg
    31501 caacccatcg gtgcaggtgt gccaggcccg ctgtcacaac gtttgtctcg tcgttgggag
    31561 gccctggtcg ggtagcgtcc cttgctttca ctcctatggc atggtaaggt tcctccgctg
    31621 taagtgggcc tgggcccact tttttgtttg agcaactttt gcctatgagt gatgcgggag
    31681 cggtgtcggc agggaagcct ttggtgaaac gcgctgaggc gctcaacctc cgcgtgcaag
    31741 aagttgcggc tcccattctg caatcccacg gccttgagtt ggtcgaggcg gtatgtgtcg
    31801 gccaaggtcc ccggaccgtg atccgggttt tcatcgacaa gcccggcgga atttcgctga
    31861 ccgactgtga gcaggcgcat cgctctctga gcccggcgct ggatgtcatc gacccgtttc
    31921 cacatgccta tacgttggaa atttcgtcgc ccggcctgga tcgccccctg cgaaccgcgc
    31981 atgattatcg gcgtttgatc ggcgagccgg tgacgctcaa attgcgcgag ccgattcagt
    32041 cgcagtggcg gctggtgggg accgtgctgg aagtggagga tggcgcggtg acgctcgcta
    32101 tccagcagaa aaaaacgacg gagacgatcc gggtggagtt tgatcacatc gccgtagcgc
    32161 gtcggaaggt cgaattttcc aagtagcaga cggtgcccgc tgctctgtta accatgaggt
    32221 gtgagctatg aaccgagagt tgatcgccgt catcgatgaa atcggccgtc aaaagggaat
    32281 cgataaggcc agggtcattg gcgcgatcga gtcggcgctg caaaccgctg cgaagaaacg
    32341 attcggccag gccgagaata tccaggtcga aattgatagc aagaccggcg aaatttcggt
    32401 cgtgtcgaag aaaatcatcg tcgatacggt ggccaatccg aaggctgaga tttccctgaa
    32461 agaggcgcgt gaatatgatg agggcgcgga agtcggtgat gaaatcggct ccctcatcga
    32521 aatggacgaa ttgggccgca tcgccgctca aacggccaag caggtgattt ttcagaaggt
    32581 ccgggaagca gaatgggaag ccgttcaaaa ggagtattcg acccgtcagg gagacttggt
    32641 gaacggcatc attctgggca tggagcggag aaacttcctg gtcgatctcg gcaagacgga
    32701 ggcgattctt ccgattcagg agcagatccc gcgcgaaacc taccggaggg gagatcgcgt
    32761 gaaggccttg ctgctggagg tgcgtcgcac accgaaggac gtgcaggtca tcctttcacg
    32821 tagccatcct cagtttgtcg cgaagatgtt cgagctggaa gtcccggaag tcggcgagaa
    32881 aatcgttgaa atcaagtcga tcgtgcgtga gccgggtgat cgtaccaaga ttgcggtgtc
    32941 atctcgcgac aaagcggtgg atccggtcgg agcctgtgtc gggatcaagg ggtcgcgtgt
    33001 gcaggcggtg gtgcgagagt tgcgtggtga aaaaatcgac attatcacgt ggacacagga
    33061 tcctcgcgtg ttcatcgcgg aagcgttaaa tccagcgacg atcgaaaaag tcggcatcga
    33121 tgaagaaaag aagtcggcac tagtggtcgt ggcggattcc cagctttcgc tggcgatcgg
    33181 gaagaacgga caaaatgtcc gtctggccgc gcgtctgacg ggttggaaga tcgatatcat
    33241 cagcgcgact gaatacgaga aggaaaaggc cgagcgggat cgggacatta aggcggcctt
    33301 ggccgaagag accgaggctc agcgccagca ggatgaggca cgagctgcgg cgcagcaagc
    33361 ggagtaaaag ggctcgcaac tcacgagctg aatggcaatt atctaagcgg gtggagctga
    33421 gcggtactgt atgcgcgtgt acgaattagc aaagcagctg gggatggaaa atcgggagct
    33481 gattcctgaa ctgaagcggc tcgggattcc ggtggcatcc cacagcagcg cgttggatga
    33541 cgattcggtc cgcatggcgc ttgaaaagct tggctcgaag gcgcgtgccg gtgagacgtc
    33601 ttcttccggg catgaggcga agaagatgac acgtttgccg aaagagtccg ctggatcgca
    33661 cgcagccgcg catgaagagg cgccgaaacc cgacaagaag cgcattctca tcaagaagaa
    33721 gcgtgaagag ggcgcagaag atgtcgcggc gtcgcttgcc gcagcggaag cggtgtttgc
    33781 cccggctgct cccgcagcgg cagacgccgg agttgtggat caggcccccc tgccaggttc
    33841 tgaagtgagt gaggctggtc cgattgaacc ggttcaggcc caggagcccg agcctccgcc
    33901 gcccgttgtc gcgacgtccg aagatgtgac gaccaagccg tctcaggctc ctgtggtcac
    33961 gactcctcct gtcgatcccc ttgccgcaat caagaagaaa agtctcgttc ccgatgcatc
    34021 agaaagcgaa gccgctgcgc gcgagaaatt gaaaaaggca aaaaaggcgc cccggacccg
    34081 ggaagaagat gaagccaagt ttaagaacga cgccactcgg tggggagatt tgcgggcgat
    34141 cccggtgcag cggcgtgagg accggtccaa acatattcac catgcctcgc caacggaaat
    34201 caccaagccg agaaagaaaa gcgtgaaatt gaccgcagga gtcagcgtca aagagtttgc
    34261 ggaactcatc ggtcagcggc cggcggacgt ggtccggaag ctgatggata tggggcagat
    34321 ggtgaccttc aaccagtcga tcaatctcga ggcggcgtcg ttgattgccg aagagtatgg
    34381 cgccagggtg gaagtgtcga cggagaaagt cggcgaagcc ttgctggaag aggcggcgca
    34441 gtcatccggt gaagagcacg cggtgtcgcg gcctcccgtc gtcacgatca tgggccatgt
    34501 cgatcatgga aaaacgtctc tgctggacgc gattcgttca acgaaggtcg ccgaaggcga
    34561 agccggaggg attacgcagc atatcggcgc ctatatcgtc ggggttcatg acaagcaggt
    34621 cacgttcctc gatactcctg gccacgaagc gttcaccgcg atgcgggcac ggggagcgaa
    34681 ggcgacggac atcgtcattt tggtcgttgc tgcagatgat ggcgtcatgc cccaaacagt
    34741 cgaggccatt catcatgcca aggctgccgg cgtaccgctg atcgtcgcca tcaataaagt
    34801 cgataagccg ggtgccaatg tcgatcgtgt gaaaaatgcc ctgaccgagc atgggttggt
    34861 ggccgaatcg tggggtggtg acacgattat ggtggaagtt tccgcgaaac agcggaccgg
    34921 tctggatcaa cttctggaaa tgatcctctt gcaggcggaa gtcttggagc tgaaagcgga
    34981 ccccacgcgc atggcgaagg gcttggtgat cgaagccaag ctggatcgcg ggcgcggccc
    35041 catcgcgacg gtccttgtgc aaagcgggac tttgcacgta ggcgacgcgt ttgtcgtcgg
    35101 taatttcagc ggccgggttc gcgcgttagt cacggatacg ggaaagaaaa ccaccgaagc
    35161 gggaccatcg gtgccggtcg aagtgatcgg attgccgggt gtgccctctg ccggtgacgc
    35221 ctttaccatc gtgaaggatg agcgagtcgc ccgcgagatt gcgcaagaac gagcgatgaa
    35281 gcagcgggct gctgatctgg caggcccggc gaaagtcagt ctggatgact tgttcgccaa
    35341 aatccaagag ggcaatgtca aagagctgcc gatcgtgatc aaggctgatg tgcagggttc
    35401 ctccgaagcc ttggctgctg ccgtcgagaa aatgccggcc ggcgccgtca aattgcgcgt
    35461 catgcacacc ggagtcggag ggattaccga aaccgatatc ctgctggcgg ccgcgtcgaa
    35521 ggcgattgtc atcggattca acatccgtcc tgagccaaag gccgcggcgt tggcggaacg
    35581 agagggtgta gatgtccgtc tctacagcat tatttatgac gcattgaatg atattcgtgc
    35641 cgctatggaa gggttgctcg agcccacgct caaggagcgg attctcggac gtgccgaagt
    35701 gcggcagatg tttacgattc ccaaggccgg cctggtggct ggttgctacg tggtggatgg
    35761 cgtcatctcg cgcgccagtg tcggcgtgcg tgtgattcgg gatagtgtgg tggtctacga
    35821 ggggaagctg ggctcgctga ggcgtttcaa ggacgatgtg cgggaagtcc agcaaggcta
    35881 tgagtgcggt atcacggttg aaaacttcaa cgacctcaaa gcaggagaca ttatcgaggc
    35941 ctttgccatc gacaaggtcg cggcaaagct cgaatcggca caccgcggca cttccccgca
    36001 acctcatcgg gcatgatcgt cgggctttgc acggtcgagt tgttcatccc cgatggacat
    36061 tcattgaaag acaagcggca ggttttgcag agtttgaaaa gtcgcttgcg ggataagttc
    36121 aacgtgtcag tggctgaagt aggagagcag gaattgtggc agaaggcgat tttgggattg
    36181 gcctgtgtgg cgaatgaatc tgcccacgtc aaccaggtgc tggaccaggc tgtgaatttg
    36241 attcaggggg tgcccacgat tcagctgctc cgctctcgga tcgaattgtt gtaaggccac
    36301 gtcatgacga aatcgacgta tagtcgggcc gaacgggtgg ccgatcagat ccgcatggaa
    36361 gtggccgaca tattaatgcg caagatcaaa gatccgcgcg tgcgttccgt gacggtgacc
    36421 gatgtggagt tgaccaaaga tttgcgcatt gcgcgtgtct ttgtcaccac catggagcag
    36481 aacaaagacg agcggctggt atttgacgga ctagcgaaag cgagtggttt tgttcgggcg
    36541 gaactagggc ggcgactggc gttacggtat ctgccggaat tgatttttat gaaagacgtc
    36601 agcggcccca gggctgatcg ggttctcgcg ctgttggacg gattgcacct ggatgaaacc
    36661 aaagaagaca ggctaccaga aacccctcgc accgatgtct agccgatgat gatcgcgtcg
    36721 acggaatccc agacggctac catgcttcag gatggcgtgc tgaatgtccg caaagaagcc
    36781 ggatggacgt cacacgatgt ggtcgcccgt gttcgaggga aattgcgcgg aatgaaactg
    36841 ggccatgcgg gcaccctcga tcccgctgca accggggttc tcccgctgct ggtcggccgt
    36901 ggcacgcgca tcgctgaata tctgctcgaa tgggataaaa cctatctggc cggactgcga
    36961 ttgggtgaaa cgaccgatac gcaagatgcc actggaacgg tgctccagcg ctcgcctatt
    37021 acggctttga ccgaagctcg tatccgggaa actattgctg ggtttgaagg ccgcattcaa
    37081 caggttcctc ccatgtattc agccgtgaaa gtgggagggg ttcccctcta taaagctgcg
    37141 cgagcaggga aggatgtggc ccgccagcct cgtgaagtca ccgtctttcg tttggaagtc
    37201 gtcagcattc agctgcctga tgtcatgctc cgtgtggtct gctccaaagg aacgtatatc
    37261 aggacgctct gcgcggatat cggagaaaaa ctcggggttg gcggtcatat ggcgaccttg
    37321 atacgcgaac gcgtcgggcc gctgatggta gagcagtcct tgaccgtcaa tgaagtcgag
    37381 acacgcctga ctcaggggac gttggccgga tcgatgctca cgttggatga ggcgttggta
    37441 ggacttccag tctgcatcat cggccgggag actgcacggc aggtcgtaca tggcatggca
    37501 gttccgaccg ccgatgtgtt gagttggcag ggcttgccga ccattctccc ggaagcctcg
    37561 ggtggaccca tccgtatcaa ggacacggct ggacgattgc tcgcgatcgg caccatgccc
    37621 gccggactcg gcgaccaggc caggatgccg ggcgagctgt cgattgcgat gtcaaaggta
    37681 ttagtcgagg acgagtcaca gggtagtagt attgcgaact caatagagga gtagagacgt
    37741 atggcactgg tcaaagaagt gaagacagag ttgatgaaga attttcagca gcatgacaag
    37801 gacaccggtt ctccggaagt gcaaatcgcc attctgacga accggattac gtatttgacg
    37861 gaacatttta aattgcacaa gaaggaccac cattcccggc gtggattgtt gacgttggtc
    37921 ggacgccgtc gccgcttgtt ggattatctc cggcacgtcg aagaaggccg ctatcgcgcc
    37981 gtgatcgaac gtctggggat ccgtaagtag tcgtgtgatc gaatcggccg ccacatgtgt
    38041 ggcggccgaa ctattgtccc cgcaggtgaa cactgaaaca agttcaaacg catgggccat
    38101 ctaggggccg cattcgaatt gagcttatct ctgtgggcat ctgtgggatt taacgggagg
    38161 agaccataga tgaaacaagt agtagatatc gagctggcag gtcgccgctt gacactggag
    38221 accggccgta ttgccaaaca ggcggacggt gcgatttggg ccacctacgg cgacacggtg
    38281 gtgctcgcca cggctgtcgc ctcacaaaac gcgaagcctg gtgtggactt tcttccgctg
    38341 acggtggatt accaggaaaa gacctacgcg gccggcaaga ttcccggcgg gtatttcaag
    38401 cgggaagggc gaccctccga gcgggaagtg ctcaccagcc gattgatcga tcgtccgctg
    38461 cgccccctct ttcccgaagg ctactatttc gaaacccaag tcatcacttc ggtgctctcg
    38521 gctgataaaa ccggcgtgtc cgatgtgatt gcgatcaccg ccgcgtctgc cgcgttggcc
    38581 atttcctcca ttccgttcaa tggccccatc gcaggtgtga aaatcggtcg ggtgaacggc
    38641 cagtttgtcg tgaatcccga cttggaaacc cttgagacga gcgatctaca tctcgtggtg
    38701 gcgggcactg ccgacgctgt gatgatggtc gaagcgggcg ccaatgaatt gcctgaagcg
    38761 accatgctgg aggcgatcga gttggcgcac agcgagatta agaaaattgt cgcgaagatc
    38821 gaagagcttc gtgccctggc cggtaagccg aagcgagtag tgacgcaaga accgatcgac
    38881 gctgccttgg ccgaacaagt gcgcaagctg gtggcgggcc cgattcgtga agccatactg
    38941 attcccaata agagcgcacg gcaggagcga ttggatcagg tcctggccga gacgcttgtc
    39001 gcgcttaagt cggaagagcc caaccgcgac cggcatgtca aaatcatttt ccacggcttg
    39061 gagtacaccg aagttcgcaa catgattctc gagaaacggg tgcgtgccga tgggcgcggt
    39121 ccgtcggaca ttcgtccgat cacgtgcgaa gtgagtgtgt tgccacgcgc gcacggctct
    39181 gcggtattta cccgcgggga aacgcaaagc ttagcggtgg tgacgttggg aaccactgac
    39241 gatgagcagc gtatcgacgc cttggaaggc gagtacatgc gcaccttcat gttgcactac
    39301 aatttcccgc ccttcagtgt cggcgaggct aggccgttgc gatcccctgg gcgccgcgaa
    39361 gtcgggcacg gggcactagc agagcgcgca ttgaagtcga tcatccccgg gaaagataag
    39421 ttcccctaca ccgttcgaat cgtgtcggaa attcttgaat ccaacggctc ctcgtccatg
    39481 gccacggtct gcggcggaac gctggccttg ctggatgcgg gtgtgccgat caaggaaccg
    39541 gtggcgggca tcgcgatggg cctgatcaag gaaggtgatc aggtcttggt cctctcagac
    39601 attctcggct tggaagatca tctgggcgat atggatttca aggtgacggg gacgaaaaac
    39661 ggagtcaccg cgctgcagat ggacatcaag atcgggggaa tcgacgccgc gttgatgcgg
    39721 gaagcgctgg cgcaggccaa ggccggtcga ctgcatattc tgggctgcat ggcgcaggcg
    39781 ttgacggctc ccagggccaa gttgtctgcc ttcgctccgc gcatattccc gatgaagatc
    39841 aagcaggata agatccgtga tgtcatcggc ccaggtggaa aaatgatccg cagcatcatc
    39901 gcggagaccg gtgtgaagat caatgtcgaa gacacgggcg atgtgacgat cgcgtcctca
    39961 gacgaagcct cggcacagaa ggccatcgat atgatcaagc gtctgaccga agaagtcgag
    40021 gtcggcaaga tttatctggg gaccgttcga aagattatgg atttcggcgc cttcgtcgaa
    40081 gtgcttccgg gcaccgacgg tttggtccac atctctcagt tggcgcacca ccgcgtcaag
    40141 gcggtcaccg atgaggtcaa ggaaggtgac cagatccagg tgaaagtgtt ggaaatcgat
    40201 aagcagggga aaatccgttt gagccggaaa gaagcgatgc cggcacctgc gggctctccc
    40261 gcaactgagc cgactcccgc aggataatcg atcgtgtatc gcaagatcgt tctcgacaac
    40321 aagttgcggg tcgtggccga attactgccg acgttgaagt ctgtcacgat cggcatttgg
    40381 gtcaatgtcg gctcccgcga cgagcagccg ggcgaggagg gactgtctca ctttctcgag
    40441 catatgtttt tcaaggggac gcgaagccga tcggcgacgc agatttcccg tgaaattgat
    40501 gcgctgggcg gggagatgaa tgccttcacg actcgcgaga cgacgacgtt ttatgtgaaa
    40561 gtgctcgatc aacaattgga agcggcgttg gagttgctct ccgatctgtt ctaccgttcg
    40621 cggttcgagt ccaaggaagt cgaaaaagaa aaacaagtgg tgctggaaga gatccggatg
    40681 gttcaggatg atccggagga tctcgttcag gaactccaca tgaagcatac gctcggcagt
    40741 cacccgttgg gccggcctat cctggggcaa gctccgagaa tccaggcgtt gggtcgtcag
    40801 gacctggtct cgtatgtcgg ttctcactac gatcctgagc gcacggttgt tgccgttgcg
    40861 gggaacttca cctggaagcg cctcgaacaa ctcctggccc gctacttctc cgcccctcac
    40921 aaaggcgtcg cggtcaagca gagtcggcgg ccacccgaag tccgtggagg agtgctggtg
    40981 aggcgtaagg cgttggagca ggtccatctc tgtttaggcc tgcagggatt gggcgctgga
    41041 cataaagatc ggtatgcggc tcatgcgctc aatggagtgc tgggcggaag cgtgagttcc
    41101 cgcctgtttc aggaggtgag agagaagcgt ggtctcgtgt attcaattta ttcgttcctg
    41161 tccacatact cggacggcgg gatgacgacg gtgtatgccg gcacgcgccc gaaagaggtg
    41221 gagcgtgtag ttgaggtcgt gtgccgggaa ctcaagaagc tgcgcagcaa ggggattgat
    41281 gcaaaagatc tcgcccgcgt gaagaatcaa atgaagggca gtctcatgct cagcctggaa
    41341 agctcgcata gccggatgag taaactcgcg aaagacgaat tgacgcaagg gagtcatgtt
    41401 tcgctcgaac aaatgatcgg ggagattgac cgtgtgacga cggatcaggt ctatcgtgtg
    41461 gcccagacct tgttggatca gcggtgtctc gcgatcacag cgcttggacc cataccggtg
    41521 aatagccttc agtcgtttgc gtcataatag atcacgcgcc tgcatctcct cggtcggcgc
    41581 agcaactgag cgtgagagag aagcaaccat cgacgtgctt ctgaccgcta actgattgat
    41641 cgggcggcat tttgatcgtg gcaactgccg tacaattttc gaaaaacatt ttcttgacac
    41701 gtttggtgga tttaagtacc atggccgcgt tttcatccta tacgttcgaa ttcatttcga
    41761 ctgcattaca ggggaaggta agcagagaga aagggggtgt gtgtcgcact tcctcctgct
    41821 agcgcgttct ctgaattttt ttgttttttt tgaactcttt ttttggatac tgtgattcaa
    41881 cggttctctg gtcatcattt ttccaaggag ggtagggtta tgaatagggt cggaattcta
    41941 gccgcacttg cagtctcctc cgttgtcggc ttgttgaccg ccggtgtctc aatggcggcc
    42001 gacgctccag ccgggggcgg acccagcgaa gtcaccacgg gcagtggtaa gtttttcaaa
    42061 ggcgaaccca cgaatacctt gaagggtcgc gtgtggtcgc agtgggccga caatcccgac
    42121 ggtgaaattt tgttcggcat tcaatattgg aatacgggag atcccgcttc aggtgagggt
    42181 ggtggtcgtt catcaacctc catggatgtg aagccgccgg accccctctt tacgtgctgc
    42241 gcctggggct acactggtgg cacggacaag aataatccgt acgccggttg gcaccatgct
    42301 cagaccacgg ttcggttggc cgtgaaggac aagggcttga tggatcagat catcaaggct
    42361 tcccaagagc tcgttgcgat ggaagtgacc ctcgacggtc gcacgattac cggtttcaaa
    42421 gtattgaagt agattttata cgcgaggcga cattcttgag actcttttgt cttctttaag
    42481 gaggatgtga tgatgaagct tcaaaagcaa gggtggacct tcatggctgc cgcagctttg
    42541 gtggtaagtt ttgcctccac tgcgctggcc atcgaggcgt tccaggagag atttgagtgg
    42601 ggagatctga gcaagcccac cacgttgcag ggccgagtga tcatcttgga tccgtatgat
    42661 gaggccgtgt ggctcaacat cgcggtgttc ggtggcaacg ccgaaagcgg attgtggtgg
    42721 cagagagtcc atcctggaaa gaacctcaag ttctatcctg cggataagaa cgtgtgggaa
    42781 cagctgaagt ccatggcccg tgcgcattcc ggaccggccg cggcaaagga agttcctcct
    42841 ggatccccga cgaccttagt ggagtttgtg gcccaggaaa ccgagcagaa tcaccgggtg
    42901 atcacatccg tgaagaagct caatgacaac gccggcgaaa tgggcaagcc gaagagcatt
    42961 tcatcccttc gtttgaagga atgtgaaggc aagacggaag tggatgctgc ttgccatgcc
    43021 gcaaagacgt tgttgaacac gtcgccgaag actccggatg gagccaattt gcccctgcag
    43081 tatgatgtct tgttgcctga tggcaagcca attgccaatc tgattccttg gaccgccaag
    43141 tacaatcagg gcagcaagca ctaagttcta gcgagttatg cgctcatgaa gaaggcggca
    43201 ctccgaaagg ggtgtcgcct ttttctttgg ccggagtgaa ctgaagtcga agccgctcga
    43261 tgcggaatcg ttactcgctc aaaagccgtt gttggagtgc agccagccga ttgagggcat
    43321 cgaggggtgt catggagaag aggtccattt ggcggacttc ttccagcatg ggatgcgggg
    43381 cagggagagt ggaatcaaac tgtagagctt gctgactttc aagaatggga cgtggtgctg
    43441 ttgtggattc cagttgtgct agtacagcct tggctcgctg tatgaccgcg tccggaaggc
    43501 ccgccagctg ggcaacatgg ataccgtaac tacgatcagc gcctccttgg acgatcttgc
    43561 gcagaaataa cactttcccg tcgcgctcct tcaccgccac agaataattc gtgattcctg
    43621 ctcgtaatcc ctccagctga gtcatttcat gatagtgagt tgcgaagagc gtgcgagctc
    43681 cgagtcgctg cggatcctgg atgaactccg caatggccca ggcaatgctc aacccgtcgt
    43741 aggtgcttgt cccacggccg atttcatcca gcaaaatcaa gctgcgtgcg gtcgcacagt
    43801 gaagaatatg agcagactcg gtcatctcca ccataaaggt actttggccc cccgcgagat
    43861 tgtccgatgc cccgacccgg gtaaagatgc gatcgaccaa ccctattctg gcctcggctg
    43921 cagggacgaa actgccgatc tgtgccatta acgcaatgag tgccacctgc ctgaggtagg
    43981 tgcttttccc cgccatattg gggcctgtca aaatgtgaag gcggctggtg tgcagatcca
    44041 ggtgcgtgtc gttggggata aatcctccgg agagatcaag tcgttcgacg acggggtgac
    44101 ggccttgctt gatgtggagt acatcgcccg tgtcgatggt gggtcgcacg taacgattca
    44161 acccagccgt ttccgccaac gctgtgagga catccagaac cgccagtctg cgactgatct
    44221 cttgcaggcg ggctgtttcg gcggcgaggc ctgttctgag ctgttcgaaa agcgattgct
    44281 cgagagccac gagtttggca tcggcaccgg tgacccgttc ctccagttcc tttagctcag
    44341 ccgtcataaa tcgctcggca ttcaccagtg tctgcttacg aatatagtca gacggaacct
    44401 tgccgagatt ggctttcgtc aattcgatat agtatccgaa gacctggttg tagcgaattt
    44461 tcagagactc ggcgccggtc cgctcccgtt ccttggcctc cagtcctgca atccaacctt
    44521 tcccttcacg agtggctttg cgaagctcgt ccacatccgg gtgatacccg tccttcaaaa
    44581 tgcccccgtc gcgtatagaa actggagcgt cggcaagaat ggcttgttca atcagttcat
    44641 acaagtcctg cgcgttgtcc caggatgctg agagctcggc gagaagcggg gcctgcaacg
    44701 gcgtgagttc ggcctgaatg gcaggcaggg aggataacga gagtttcaag gccagcaagt
    44761 cgcgtggatt cgcgacgccg agcgagattc ggctgcagag tcgcgaaata tcctggacgg
    44821 tgcgtagcgc cgttcgcaat cgaactcgtg gctcgatgct ctctttgagt tcctcgaccg
    44881 ctgtgaggcg cgcttcaatc ggggcgcagt tgattagtgg gcgcagaagc cattcgcgga
    44941 gcaatcggct tcccattgcc gtgaccgtgc gatcgaggac acctaacaat gtatacggtg
    45001 agcggtgatt cggcgcgtcg tcccagcgtc ctgcgggttt gacgagttcc aaatttcgga
    45061 tcgtgacact gtccagatgc atggcgtcgt gaggctgtct cactcgcaag ttccgaatat
    45121 ggtcgagtga ggccgaaggt tgggtctccc tcacatagcg cagcacggcc gctccggctt
    45181 gaatacccaa tgtgagctgc tggcacccga aggagtctag cgagtgcaca cggaagtgtt
    45241 cctgcagcat tgcgcgaccg gtatccagct caaaccatgt tgccggttgt gcgcaacagc
    45301 gaggtccgat taattcagct atccaggatt gtgctcccgg tgtgcaccct tcggcataca
    45361 gcaactcttt cgggtcaagc cgtgcgagtt cgtccatgag tgcgatctgc gcttgcggac
    45421 catgaaactc gcaaagccag tactctcccg tggaaacctc tagcgtcgcg agaccgaatg
    45481 aacagcctgt aggttcgtgt gtcgcaggcc gcaagcggat ggccacggct gccaacagat
    45541 tggattccga tgaggggagg aattcgctat cgatcagtgt gccgggcgta tagagccgga
    45601 cgacctcccg tctgaccaga cccttggcaa gtttcgggtc ttcgacttgt tcgcacaagg
    45661 ccaccgttcg gcctgcgcgc aagagcttgg cgatataatt tgttgcggcg tgatagggga
    45721 cgccgcagag cgggatcgga gtttcgctgg atttatcgcg ggaggtcagc gcaatcgaaa
    45781 gaagcttgga agcttcgacc gcatcttcct gaaacatttc atagaagtcg ccgacccgga
    45841 agaacagaat agcatcacgg taggcctgtt tgatctcgcg gtactgccgc atcaacggcg
    45901 tgccgtctgc ctcacccatc gacgggttct ccctccgtag ggatgtcaga agagcttcca
    45961 acgcggcggg cggctttgtc gagcgcctgg cgcagccgtt cgagatcgac ttccgcttcc
    46021 tgcaaggcct tggtttttcg tctgagctcg attcgcccgc ggacccaggc gggaaaaagc
    46081 agaatgccgg agaccagcag gccgacgccg aaggccgcca ggatcggctt atagatgaga
    46141 attgacgccg atcgaaggcc gaagaaatac cggagagtga cctcctgttc ttgattctga
    46201 agaaagaacg acagcgccag cagcagtacc gtccctacca atatcaagcg gatcaatgcg
    46261 aggccctccc tggccgaggg tcattgtaca cgggtttgcg aaaccactct agtgggacga
    46321 cgcacggaca tgcgagagcg aagggcgagg agcaggcgtg atgcagacgg gcctctggct
    46381 gtgagcaccg cctgtcgcgt ggacgggggg tgatgggtaa gataaatctc aagccgatca
    46441 tgcggaagcc ctgcgcccca gcgttcggcc cattcaacag cgagaatagc gcggccgtct
    46501 acgtagtcac ccaggcccgt attctcgagt tgggcggcag tgaggcggta taaatcagta
    46561 tggatcagag gaaggcggcc acggtattcg tgaattaagg taaaggtcgg actactcaca
    46621 gccatgggtt cggcgccaag tccatcggcg atgcctcgaa ccagtgacgt tttcccagta
    46681 cccatttctc cgaacagggc cacaacttcg cctccctcaa ggagggtgcc cagacatcgg
    46741 cctagccgat gagtttgctg ccgggagcga aggagcgttt tccagggttt ggtgacagcg
    46801 ggaggccttg ccttcttccc tcctgcaggt gaagtggtca acagcttaga ggtgcgtggt
    46861 tggcgcgatg gcatggggga tatggcgaat cagatcgcgg gcaatcatgc cggcctggcc
    46921 gagttgctgc gcggcgagat ctccggcaag gccatgaaaa taggtggcgg cacaggcggc
    46981 gtcccaggga gccacacctt gggcgagcaa cccgccgacc atgccggtca acacatctcc
    47041 ggttcccgcc gtggccatgc ctgggttacc ggttgggcag atcgctgcga ccccgtccgg
    47101 tctggcgatg acggtccggg ctcctttgag aacgacgaac acgcctcgtt cacgtgcgaa
    47161 gcgcgttgct gtcccgaggc gatcttcatt gacggactgg gtggtggctt ctgcctcaag
    47221 cctcgccatt tcaccgggat ggggcgtaat aatcggcggg cgagggcatt ccgtgagcaa
    47281 ggacgccttt ccggccaagg cattaagcgc atcggcatcg agcacgcacg gcttatcgat
    47341 gcgcttcacg aattcttgta ccaagtccac cgtctcggga tgcgtcgtca gtccaggtcc
    47401 gatcgcgacg gcatcgcgag gacccgcgaa tgccaggagg cgatccaggc ctgaacgggc
    47461 aaaggtgcgg gccttggtct ccggcatcgg cagggtcatg gcttcgagta atttcgcctc
    47521 gaggatgtca ttgacgctcg agggaacggc agccgtgacg agaccggttc cgattcgaag
    47581 ggcggccatg gctgccatgg ccgcggctcc ggttttgccg accgatccgg cgatgatgcc
    47641 gagatgtcca taggtgcctt tatgcgagga cgggtgtcgc gggggaagcg ccgcgttcgc
    47701 ggaggcagcg gtcaggagca gcagccgact gccgacggcg tcgacaaacg aagacggaat
    47761 tccgatgtca gcaagacgca ccaacccagc gcaatcgatg ccgcctccgc aatagagtcc
    47821 tgcctttggc aatccaaagg tcacggtgag gtccgctttg accgccgtgc ccaggacaga
    47881 tccggtatcg gcatgaaggc ctgacggaag atccacggcg acggtgaggc gtccagcggc
    47941 attgatggcg tctatcgcat cacggtataa gccggtcaca ggcgtggaga ggccggtgcc
    48001 taaaatggca tcgataatga tctcgcttgg tgtcagccgt tgttgaatgg cgttcgtatc
    48061 agaggggcga gtaatggaag atgggcctgc tgtccggtga aagcgctgat acatcgcctt
    48121 cgcatcgcgg ctgagttcag ccaccggtgc taataacaac acgtggactc tagctttttt
    48181 tctccgtaac agtcgagcga cgacgaaacc atctccaccg ttattgccct tgccacacag
    48241 gatgacgatc ttttttcctg caaccgatcc gtatcgcgcc tcaagatgag tcaccacacc
    48301 tgttccggct cgttccatca gtacgaggga cggtacctgt gcctcggtga tcgtccgatg
    48361 gtccagtgca cgcatttgct cggcggtcac gatcggtatc atgacgtcaa tcgggcctcc
    48421 gattcgggac tgagggagga ccttgcctgg ggaaagccag gctaagccac caattctttc
    48481 atttcacgga cagcctgaac gagccccacc atgacggagc gggcgataat gctgtggccg
    48541 atattgaact cgacgatctc cggcagtttg gcgagtcgtt tgacgttctt ataggtcagg
    48601 ccatggccgg cgttcactcc gaggccaagt ttgtaggcta gttttgccgc ctgagtgatc
    48661 gcttcgaatt cttcgtcttc ttctttcgag cggtttgcgt tcgcgtaacg gcccgtgtga
    48721 agctcgacat aggccgcgcc gattttatga gcggccttga tttgatccaa gctaggttcg
    48781 atgaacagac tggtcgggat cccgccatcg cggagcaaat cgacgatctt ttggattcgc
    48841 tcgcggtgat tggcgacatc gaggccgccc tccgtagtca gctcttgacg acgctccgga
    48901 accagcgtga cgaggtcagg tttcacactt agcgcgattt tggccatggc gtcatcggcg
    48961 gccatttcca gatctagttt agtgcgaacg atttcccgca atatcgtcag atcgcggtct
    49021 tgaatatgcc ggcgatcctc ccggagatgc acgacgagac cgtctgcgcc ggccagttcg
    49081 acgaggatgg cggcagtcag agggtcgggg tcggttccgc cacgcgcttg ccggagtgtt
    49141 gccacatgat cgatgttcac gcccaatcga gccattacgc ctccgcaaat accatgaatg
    49201 acgatgcaga aagatttcgg aactggtcga aattcataga caattctgtt gttcctgagg
    49261 cattattaac agaagacagt ggggcggggc aagaaggctc tggtcaaggc gctgccgcgc
    49321 ttttctcacg ttcatggccg agcggcaagc cgcaactcca tagaaatata gtgaaattga
    49381 ctcgttttga gggctctatt aaaatacgct cctttcagag gcgtcacgac gcaacccgtt
    49441 cagcagaggc cccgccagta ggagtctgac acatccatgt cgatcagcga cggtttttac
    49501 cgcatcaaac gacttcctcc gtacgtattt gcccaggtgc aatccctgaa actcgaggcg
    49561 cgtcaacggg gcgaggacat catcgacttc gggatgggca atccggatca gcccacgccg
    49621 ccccatattg tcgacaaact gatcgaggcg tccaggaaag ccaagaatca ccgttattca
    49681 gcctcgcgtg gcattaccaa actgcgtcac gcgatcactg gctggtacaa gcgtaactac
    49741 gatgtggatt tggatcccga gaccgaagcg attgtcacga tcggctcgaa ggaaggtctc
    49801 gcacacttgg ctttggccac catcgggccg ggcgacgtgg tcctgacgcc gactccgacc
    49861 tatcccatcc acatgtacag tttcattatc gcgggtggcg aggtgcgtgg catcgagctg
    49921 cgtcaggaca gcgatttctt cgacgatcta ctgcgggtct atcgccaaac gttgccgcgt
    49981 ccgcgtattc tggtgatcaa tttcccgcac aaccccacga ccgccgtggt cgatctcgag
    50041 ttctttaaga agattgtcgc gtttgccaaa gagcacgatg tgatcgtgat tcatgatttg
    50101 gcctacgcgg atatcgcctt cgacggctat aaggcgccga gttttctgca ggtgccggag
    50161 gcgaaggatg tgggcgtcga gttttatacg ctttcgaagg cctacaatat gccgggctgg
    50221 cgcgtcgggt tttgtgtcgg taaccgtgaa gtggtaggcg cactcgcgaa gctgaagagc
    50281 tatctcgact acggtatttt ccagccgatt caaatcgcca gtacggtagc attgaatgga
    50341 ccgcaggact gtgtgaaaga cgttgtgcaa cggtatcaaa accgccggaa tgtcctggtg
    50401 aacgggctga atcgtatcgg ttggccggtg gcgttgcctc gggcgacgat gttcgtatgg
    50461 gctcgtattc cggatccgtt tcggcacatg gggtcgctgg agttttcaaa attgctgctc
    50521 cgtgaagcga aggttgcggt atcgccgggc atcggcttcg gcgaaggcgg cgatgaattc
    50581 gtccggtttg cccttgtgga aaacgagcac cgcacacggc aggcgttgcg cgggattcgg
    50641 aaagtgttga atttggatga tcaggaacca tgaagactga gatcggagta ggactgatcg
    50701 gcttcggtac cgtcgggacc ggcgtggctc gagtgctgat tgagaatgcg gaattgatcc
    50761 gtcggcgggt gggcgtgccc atcaagttgg tgcggattgc ggatttggac attacccgtg
    50821 accggggcgt ggcgattcct tcaggtgtat tgaccacgga tatccagcaa gtgctggaag
    50881 acccgcgcgt cgatattgtc attgagctca tgggcgggta tgacctcgcg aaacgcgtga
    50941 ttctggatgc ggtgcaacga ggcaagcatg ttgtgacggc gaacaaagcg ctcttagcgg
    51001 tgcatggaga agagattttc gctgccgcgt cgcgtcgcgg gatcgacctt ggattcgagg
    51061 cgagcgtggg gggaggcatc cctgtgatcc gcgccttgat ggaaggtttg gccgcgaaca
    51121 atattcaatc catttatggc atcatcaatg ggacgtcgaa ttatattctg agccggatga
    51181 ccagcgaagg acagcggttc gaggtcgtgt tagatgaggc caaacgagcc ggttatgccg
    51241 aggcagaccc cacgttcgat gtcgcgggta ttgattcggc ccataagctg acaatcatgg
    51301 tgagcctggc ttacggcact ccggtgaact tcaaggagat ttataccgaa ggcatcaccg
    51361 gccttacccc gctggatatc gcctatgcca aggagtttgg ctttaccatc aagctgctgg
    51421 cgattgcgaa gtgttccgat ggagaaattg aagcacgcgt ccatcccact atggtgccgt
    51481 cggcgtcgca aattgcgaaa gtcgatgggg tgtacaatgc cattcagttg gtgggggatg
    51541 ccgtcgaaga cgtcgtcttg tatgggcgtg gcgccggatc gatgccaacg ggaagcgcgg
    51601 tcgtcagcga tgtgatgtcc atcgcccgcg acctactcaa ggatgcgacg ggccgggttc
    51661 cgccagcctc ctatcagccg gactatcgaa ggccgctgcg tatccggcca atggaagaaa
    51721 tcacttcgtt atattacatt cgcttcatgg ttttggatcg gcccggtgtc ctgtctcaga
    51781 tcgcgggggt attgggtcgc tacagcatca gcatttcctc ggtgctgcag cagggacgca
    51841 aggaagggca gaccgtgccg gtcgtcatca tgacgcatat ggcgaaagag cgtgatatcc
    51901 aacatgctct tcgcgagatc aatcccatgc cctacatctc agaaccgacg acattgatca
    51961 gggttgaggg gaaagacgaa tgagtggggc attttccgac ctcaatgaga aggtggcagg
    52021 ctagatcgtt atgactcgct ggcgcggcat tatcgaagaa tatcggaagt tcctgccggt
    52081 gacggctcag acgccggtca tcacgctggg agagggcaat acgccactca tccgcgcgac
    52141 acggctggcc aaaaaaattg ccccgggtgt ggatctttac ctcaaatacg agggaatgaa
    52201 tccgacagga tcgttcaaag atcgcggcat gacgatggcc atttccaaag ctgtcgaagg
    52261 aggggcaaga gcggtcatct gcgcttccac cggcaacacg tcggcatcgg ccgccgccta
    52321 tggcgctcgg gctggcattg ccgtctatgt gctgattcca gctgggaaaa tcgccctcgg
    52381 taagttatcg caggccatga tgcatcaggc cacggtcatc caggttgaag ggaatttcga
    52441 ccaggcgttg accatcgtca aggaattatc ggcgacctat ccggtggagc tggtgaactc
    52501 gctcaatccg taccggattg aaggtcaaaa aacggccgcg atggagattt gcgacgatct
    52561 cggtgatgcg cccacggtcc atgtacttcc tgtagggaat gcgggtaata tcaccgccta
    52621 ttggaatggt tatcgcgagt accgtgccgc caatcaaacg acgcggttgc ctcgcatgat
    52681 ggggtttcaa gccgccggtg ccgcgccgat tgtgttaggg catgtcgtga aagagccgca
    52741 gaccgtggcg acagcgatac ggatcggtaa cccggccagc tggcagtcgg cccttacggc
    52801 ggtgaaggaa tcgtccggtg ccatcgatat ggtcacggat gaagaaatcc tccatgccta
    52861 tgctttggtc gcgagggaag aaggcgtctt ttgtgaaccg gcatctgcca cctccgtggc
    52921 cggtgtgatt aagttgagcc aagccggaca attaaaagaa ggtgccacgg ttgtctgtac
    52981 gttgaccggg cacggcttga aggatgccga tacggcgatc ggcatttcac gtcagcctca
    53041 aacggtgaaa gccacccgcg atgatgtggc ccgcctcctt catgtctgat tacctcagga
    53101 acattgcatg aaatacttga tcctgcatgc cgacgggatg gcagaccttg cctgtgcgga
    53161 actcggtggg agcacgcctc tccaggccgc caagaccccc tttcttgacc aaattgccca
    53221 acgcggagaa gtggggctgt tgagccttcc ttccgatgca ggcaggacgg gcagcgatgt
    53281 caccggtgtc gcggtgttgg ggtatgatcc caaaaaatat tatccggggc caggtcccct
    53341 ggaggctgcc ggtctcggag tgacggtggg tgagcaggac gtggtgttcc gttgcacgat
    53401 ggtcacggtg cgaggcgagt ccgcctccgg cggaacagac cgtgcggctg acatcaagaa
    53461 gctgggaccg catgtggtca tggaagatgc gacggccggg ctcatcgaga cggagcaggc
    53521 tcgcgagtta gttgaggctg tcaacgaaca attgggatcg gaaagtatcc aattctaccc
    53581 cggctcaggt catcggcatt taatggtatg ggtcggaggg aaatcccgtg cgacctgcgt
    53641 cgatcctcag cagctcgtcg gacaatcgat cgccgaggct ctgccggccg gtgatggcgc
    53701 agacgtgctg cggaaaatca tggatgcctc cttttttatc ctgcgtgatc acccggtcaa
    53761 tgaggagcgt gaagaagacg ggctgaagcc ggccaattgt ttgtggttat gggggcaggg
    53821 gcgcgctccg ttgtggccgc cgctgccgga acggtatcag gtctccggag tggtggtatc
    53881 agccagtgat gtgcaccgcg gcgttggcct ctgtgccgga ttggatgcgg ccgagctgcc
    53941 ggccgagagt ggcgatgaat cagaaacgtt tgctggctgt gtaaaggcag tcgtccagga
    54001 attggcgaag aaagattttg tctatctcca tgccggtctg tcggatgatg tgctgcacgc
    54061 gaccaatgtg catgacaagg tacaggcgat tgaacgcttc gacgcccagg tgatcgggcc
    54121 gattctttcg gcgttagcga agtatccggc gtaccgtctg ctcgtggtgt gcgatcccgg
    54181 tctggcaaag gggcaaggct cggacgttcc gccgattttg tatgcgttgt gtgacggtgc
    54241 cacccaacca ccggctggct cgtccacccg ttttcatgaa caggacaaga ccatcgccgg
    54301 atccgctcct cgcgatgcga cgaaactcat gatgcgatta tttcctcgag gagcctaagg
    54361 gttgtggcac tgatcgttca gaaatacggc ggcacgtcgg tcggaaacat agagcggatt
    54421 catcgcgtcg ccgaacgggt cgagcgcgcg caaaaagacg ggcatcaggt ggtcgtggtg
    54481 ttgtcggcca tgagcggcga aacggatcga ttgcttaagc tggcgcatga agcgacccat
    54541 tccccggatg agcgtgaatt ggacatgctg ctgtcgacag gagagcgggt gactatcgcc
    54601 ttgttggcca tggagcttcg ggggcgaggc gtgaacgccc gatcgttcac aggccgacag
    54661 gtcggcattc ataccgacag cgctcatacc aaggcgagaa tttcccgtgt cacggccgaa
    54721 cgaatcaagg aagcactcgc cgcaggggtc attccggtgg tcgcgggatt tcagggcatt
    54781 aacgccagct cggatgtcac gaccttggga cggggagggt ccgatttgac tgctgtggcg
    54841 ttagctgcgg ccctcaaagc ggatcgctgc atcatttata cggatgttga cggggtgtac
    54901 actgccgatc ccaacatcgt cccggctgcg cgtcgactcg acaagatttc gtacgaagag
    54961 atgctggaaa tggcgagcct cggcgcaaag gtgctgcaga gccgctcagt tgaattcgca
    55021 gcgaaatatt ccgttccggt ggaggtcaat tcaagcttca aggaaggaaa gggaacgctc
    55081 gtgacacgtg aagatgccga tatggaaggg gtcatggtgt ccggtgtgac gggagaccgc
    55141 aatcaggcca agcttacgat tgtcggtgtg ccggatcgtc cgggtattgc tgcgcgtgtc
    55201 tttggagccg tggcgaatgc gaatatcgtg gtggatatga ttatccaaaa cgtcagccag
    55261 gcctccatga ccgatatctc cttcacggtg ccgaaggcgg atttgcgcaa cgccgtcgat
    55321 ctcgttcagc ggttgtcgca ggagatcggg gcgcggtcgg ttgccgtcac tgaatctatt
    55381 gccaaggtgt ctctgattgg cgtgggcatg cgatcccatt ccggagtggc ggcaaaaatg
    55441 tttgaggtgc tgtcgcgcga aggcgtcaac atcatgatga tcagcacatc ggaaattaaa
    55501 atctcctgtg tgatcgaaga aaagtactta gaattggcca tgcgcacgct gcatacggcg
    55561 tttggcctgg atcgcgtgtc ggcgccggcc ttgggctaat tgtcgcgagg ggaacgtcgc
    55621 tggccgagca gccttctcga cacgtcacga accgccgtgt ggctcgcaca tctatgaaac
    55681 gccgaacgac agcatcgcgc cggtcttccg ctccggactc gactaccgca ccgacgctca
    55741 ccgccgcaca agcctctgca ctggagatct acgatacgac gctgcgtgat ggagcgcagg
    55801 cggaagacgt cagtttctcc gtggaagata agcttcgcgt ggcgcaacag cttgatgaac
    55861 tcggtgtgca tttcatcgag ggcggatggc ctggagccaa tcccaaagac attgagttct
    55921 tccggcagat caaaaccatg ccgtttcgga atgcgacggt cgtggcgttc ggctcgacac
    55981 ggaaagccag caatccggtc cggaaagaca aaaaccttca ggcgctgctc gattccggca
    56041 cgcagaccat tacgctcttc gggaaaagtt ggtcgttcca agtgacggat gctctgggca
    56101 ttgcgctcgc caaaaattta gaactcatcg aagattccat tcactatctg cgttcgaaag
    56161 accggcgcgt gttctatgac gcggaacatt tcttcgacgg gtacaaggcc aatcctgatt
    56221 atgcgctgca gaccattcgt cgtgcgattg ccggcggtgc cgagcgagtg attttgtgcg
    56281 acacgaacgg cggcacgatg ccgtgggaga ttcgggaaat ttgccggatc gtaaagcagg
    56341 agtgtccggt gccactgggc attcacgcgc acaatgacag cgaaatggcc gtggccaatt
    56401 cactcgttgc ggtggagtct ggaattctcc aggtgcaggg cacgattaac ggaatcggcg
    56461 agcggtgcgg gaatgccaac ctctgctcca tcatcccgaa tctgcaattg aaaatgcagc
    56521 gtccggccct cggaaacaaa ctgacgcgac tcaaagatgt ctcgggattt gtcacggaga
    56581 ttgccaactt aatgcccaac aagcggcagc cctatgtcgg ggatgccgcg tttgcgcaca
    56641 agggtggcgt gcacattcat gcagtcctca agaatgccgc gacctatgaa cacatcgatc
    56701 ctgccgttgt agggaaccgg cgccggatcc tggtttccga ttatgcggga cgtagcgggt
    56761 tgatggaaaa ggttgaagcc tacgggattt cgttgaccaa aaatcatgcg aagctccagg
    56821 aactcgtcga gacgctcaag gagcgcgaaa gtcagggcta tcaattcgaa ggcgccgagg
    56881 gctcctttga gttgttgatg cgcaaagcga tggggagcca tcgtccgtca tttcagttgc
    56941 tgggcttcag ggtcatcgtc gaaaagaagc aggaacatgg gcttctgctg tcggaagcga
    57001 cggtcatggt gaaggtcgga gatgttgtcg aacatacggc ggcggtgggg gccggacctg
    57061 tgaatgcact cgaccatgca ttacgcaaag ccttggagaa attttacccg caactgcgtg
    57121 aagtcaaact gctggactat aaggtccgcg tgttgtctgc agataagggg accgaatcca
    57181 aagtacgggt actgattgaa tcgggggatc ataaggacaa gtgggggacg gtcggggtct
    57241 ctgaaaatat tatggaagcc agttggcagg cgttggcgga tagtatcgag tacaaattac
    57301 tgctagccgg tcgctgaagc cgttttccct ccattcggcg catataatcc ttgacaggcc
    57361 agataacctc acgtaactta tggggaaatt ctttgtct
//
LOCUS       DAOQPD010000018        56724 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_207_length_56724_cov_18.081120, whole genome shotgun sequence.
ACCESSION   DAOQPD010000018 DAOQPD010000000
VERSION     DAOQPD010000018.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 56724)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 56724)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56724
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_207_length_56724_cov_18.081120"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            354..836
                     /locus_tag="PK063_06355"
     CDS             354..836
                     /locus_tag="PK063_06355"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96703.1"
                     /translation="MAMTLDRLQARTGLSRSTIHQALHRLADPDVDIVNVVHPGGGKH
                     PGLYEIHPCSYQKVLGLSAKRVPVRRRSKTAPPDGRSIENLLAQLSAEDRADLQVVYE
                     SLQAHERKMIEEEVRARFHDIGQNPDKTTFQQGLLFYLLKQRMYGRLRSKYPTLSSPT
                     "
     gene            1296..2147
                     /locus_tag="PK063_06360"
     CDS             1296..2147
                     /locus_tag="PK063_06360"
                     /inference="COORDINATES: protein motif:HMM:NF013793.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HMZ96704.1"
                     /translation="MPNVVAVINQKGGVGKTTTVVNLAAALSRLGHPVCVVDIDPQAN
                     ASSTLGKVSPYEARVTAATLMMDNKRDEDMTAPWYDTIEKEVRLIYGHVSLTKADREL
                     PRVYPTMPSIVLKRRLEQMAFGDEDIVLIDCPPTLSILTINALVASDYYLTPMMSGSK
                     YSITGYEDLMELVRDVVDSANPALKCLGILVTQHDGRKNVCKSMRGVIERRFGDLVFK
                     TAIPLAAKIQESESLKKTIFQLDRQSNAAREFMDLGREVLARMGLGALAEPDDMDEPV
                     EVGAGES"
     gene            2144..3274
                     /locus_tag="PK063_06365"
     CDS             2144..3274
                     /locus_tag="PK063_06365"
                     /inference="COORDINATES: protein motif:HMM:TIGR00180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HMZ96705.1"
                     /translation="MTSKQVSKGKDEKPPLSKSKEAKPERQKSSHLADLEASFDRDAR
                     RIRPFALVGLDTQGGQPGPEHTTPPSQIPSTTFDSAVDGSASVSIPLGAEATASPVGP
                     KAVPIIAQEADHLRRLEEVVEVPLDRLVPSPDQPRSEVDPAADQELLESIRAYGVLTP
                     IQLRPVEDGKYEVVAGERRWRACALLGKTSIPALVRRKDRDRAAAEALVDNVVRKDLS
                     ALEEARAYQALIERYGFQQSELAERLGCHKSRISRALSILKLPESILNVFFGPESRMT
                     ATHAEALLPLAHDEPRLHAIARRASKESWTRDRIRQEIDRKPRINEGAQAVRFVERGR
                     GGDRGFMLTILFHSNKPHEIPIIEEALKQAAARIQEFRDKLT"
     gene            3700..5094
                     /locus_tag="PK063_06370"
     CDS             3700..5094
                     /locus_tag="PK063_06370"
                     /inference="COORDINATES: protein motif:HMM:NF021637.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HMZ96706.1"
                     /translation="MDADFTPPSESDEGTGSSDGIPAELIFPGTTTDHGSLSVTTPDH
                     LLSEHILGSIPLWEAKGRPTGAERASYQKQIYRDVWRNSRLCKVSLVVYGSGDLGLPN
                     SIDLEFFRGFERWTKAALSRGEPFNQLVKISGRELLEASGKGLGGASYQEMDRFFLRM
                     AGTMIGAGRDWRQEGESGGSEKRPRSNKGIVFHIFQTVVLPGQVNAEGYVADKYEVEL
                     ATWYWMSLRSGNCIVIDHELFRDLHGSITKLLHQLLHNLFYLGRGTASQKYSELVRNW
                     QIKRHSALSLVKQQLDDAHRELLEKEFISRWEYVPIRTPEGKEFEIIWEAGPAWWATD
                     KKTREFREEMVGANHRELQQIGRELDPFLLIEQSDESNQEKDGQREASNARLLSVVLE
                     ISGKRKDPKVWEKWWKRAITSVPHPMIWRRIGEVKERRLSGQTINQGSYLLSLIRGDA
                     ARLGLPWATSDKVK"
     gene            complement(5397..6212)
                     /gene="traT"
                     /locus_tag="PK063_06375"
     CDS             complement(5397..6212)
                     /gene="traT"
                     /locus_tag="PK063_06375"
                     /inference="COORDINATES: protein motif:HMM:NF017619.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="complement resistance protein TraT"
                     /protein_id="HMZ96707.1"
                     /translation="MSPIIRRTLCSAGRAFVIVVVGIATGSIFGCAGHMTLSHEVNLT
                     SSNAIFLTPSEKKTIYLQTRNTSDNPNINFGELPNKIKAKGYAIVDNPDNAQFILQSQ
                     VVLCNKLKPGQTVDALIAGGFGGAIGVAAGSAAALSGASLSHIPILGAVGAVGGFAAS
                     KLSEDSIVACVVDAMVQERTKEEIQQSITTNSMPGPGVPQSQAGAFGFLNQQSVSPPQ
                     AGQVTQQIGEIRKGTRRFHQARIVASDQKMWLSVPEASKILSDKLEDSLAGLF"
     gene            7172..8932
                     /locus_tag="PK063_06380"
     CDS             7172..8932
                     /locus_tag="PK063_06380"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ96708.1"
                     /translation="MKQIVGLGGPLPSGESYCVFLYANVPLDAKTKSLFQMVSGNISL
                     ACSAGDDQWWSARAKRGEGTPYSKEAGFAFAQGIYRRLLELNESFVVDQEKSYFEEVQ
                     ELRQSDLKMRRIADAVPGAVYQYVIARDGCQRFSYISRGAVDMVGYPADLIVSDYNAV
                     WKLVLPEDMPGIMASIEDAIRRGLRWAHEFRLRLPDGRVKWLRGDSLPEVPTADGTVL
                     FHGLLTDVTERRLAEAELRFTQFATDHAADAILWVGPDRRIMYVNVRAAELLGYSREE
                     LLNLSVPDIAPLQSRIDILNDLTRLKEGEVVQYATTFRRKSGAVFPIEVSMRCLEHDG
                     EGYVCAIVRDVSERKRAESVIQEGAEALRRSQEALRALHSQLLTAQEDERRRVARELH
                     DDLGSRLGSAILKAEGKLVLLENNSSEAAVLKNVTDELRGISDRVRTIAHGLHPSILD
                     NLGLSVALKKMVKEYGSWSGMKVVSNISMEFTEVLDREVATCLYRIAQEALMNVKKHA
                     GAQQVMIALARQDDWVQLSVKDDGMGFSPEAESRRTKGLGIVAMEERIHMVEGELTVQ
                     SGKGRGAVVVARAPYREREA"
     gene            8929..9648
                     /locus_tag="PK063_06385"
     CDS             8929..9648
                     /locus_tag="PK063_06385"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ96709.1"
                     /translation="MTASVDSSMNSPVKPISVVFADDHALVADGMTTILYGVNHKQRD
                     YEFAVVGQASSGRGLLELVKRVPADLAFVDISMPDMSGLDAVPKVREIRPDIKIVVVT
                     MHREPEYMTRALSVGANGYLMKSCSAQEFCHAIDEVMRGNAYVTSLLGSWPGGTLPGS
                     DDEEDQLASLGMSQRQREVVTLLASGKTIKETAFQLGLSRKTVEHHKAMFRDKFGIDT
                     DADLTKFAIKHGLTGIDWIRK"
     gene            complement(9936..10400)
                     /locus_tag="PK063_06390"
     CDS             complement(9936..10400)
                     /locus_tag="PK063_06390"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96710.1"
                     /translation="MASNPEIQELATEIDECAAGAFSGGRTNNLTDLALSIGAIAASA
                     IAAILVADGKSFPLFTAFVAALPALATALQQTVDFRGRATWYFIKSAQLQELSLNLKY
                     GGIVEIREAARLFGEIERRMEERWVDFVKPVMPKNSHHAAQPNQRTTSGDKQ"
     gene            complement(10599..12194)
                     /locus_tag="PK063_06395"
     CDS             complement(10599..12194)
                     /locus_tag="PK063_06395"
                     /inference="COORDINATES: protein motif:HMM:NF025085.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
                     /protein_id="HMZ96711.1"
                     /translation="MFSEDFYPTPGAVAAKMLQKINRNAVHFLEPSAGKGDLAKAILG
                     FGRTGSRYSSGSRHRVDVIELHPDLLKILQAHEELTVVGYDWLTYDGVSYYDAIVMNP
                     PFSEGALHLLRAWDFLHNGEIVCLLNQETIDNPHTEERRRLATIIAAHGSVEPLGPCF
                     RKAERPTDTPVVIVYLKKTTEDDRIHLWHTTDREQSINDDIGTPEAIPALRDTLGNMQ
                     HYYTHSLEEMFKAFAHIRKASLFMQALGTKLLPGSSIRDEADLKKILGMAQTNTTAAR
                     AEFARALRRSAWMHVFKQMDFQKWLDTKQTQELLQDLERDSTVPFTAKNIKGTLTNIF
                     LQRKRLFERSVWNVFVALTRHYKGNTTGDIGSGDGRSGWKTNDSYKVNCKLVFPYGCR
                     FWNERFDLWSTRDAGELYSDLDRVLAVLDGDKFEEIITVRDALECSFHNHGVGHRHCE
                     STFFRIRYFKKGTVHLRWKRDDLLASFNTTAAAGRQWIGTTCHNDQDSHASSPHSASN
                     TPHDWPSPAHNSPRLALTHSGDT"
     gene            complement(12681..13736)
                     /locus_tag="PK063_06400"
     CDS             complement(12681..13736)
                     /locus_tag="PK063_06400"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96712.1"
                     /translation="MSITPDAIARARNINLIEFLISRGHTPVSRRPHHADFHAPYRED
                     RNPSFSVSQRQDGTWVWYDFGRNEHEGCKHHGDLIDLVQLLDHVTFAEALHRILHNTV
                     RSMATPSGPSLAPPTDKERIAHAKKLYYAARANMTPEREEELRSYFQTLALPYNQHLG
                     AVWMRLGDEGIPYVAFPLPTPNIHFMQGLMARALGEAPPTLMRVARGLKGPWILKRSN
                     APILITESIVDCLAGDELFGPSFTLCALNGLNTGERLQDYLQRLPSRIIYIALDNDAS
                     CAAMERPPHTSQPKKGPHVQKELVSLLTHMGYHVMEVLLHHNASVKDLHKLWLKRPQR
                     VSLLDLTKTGFHHSPVR"
     gene            complement(13794..14705)
                     /locus_tag="PK063_06405"
     CDS             complement(13794..14705)
                     /locus_tag="PK063_06405"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96713.1"
                     /translation="MLNAESAFGSLWKNAFCLMLTYRKLGIQRRMDSATVLSIDTEPS
                     RVRVTKSILSCPEYMAITRLYSRVRTKLEKLTLPAGLRSGMYLIPVALAAEVDTIIAN
                     AEEELRQLVDVFLAQYDTRIAEEAARLKSAYRTSDYPDPDTVRAAFGLTYSYITFDLP
                     GTLETISATMLKREERRSMEKVNNMLEDVNTYLREAMRSLVNHLVDRLSPSDTGKSKT
                     FKSSTLTNLLEFLNTFEARNLGNDVELAQLVSSAKNVLSGVNSQLLRSDQSIAGVVQT
                     GMGTIKDQLDSLLVKRPVRLYNFDEAA"
     gene            complement(14717..14920)
                     /locus_tag="PK063_06410"
     CDS             complement(14717..14920)
                     /locus_tag="PK063_06410"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96714.1"
                     /translation="MQTDSIRITIETDGTIKLVTDEISLANHATAEDVIQQILTLSGG
                     ELERTQRLTHTHHHHHTDEHLHH"
     gene            complement(14941..15258)
                     /locus_tag="PK063_06415"
     CDS             complement(14941..15258)
                     /locus_tag="PK063_06415"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96715.1"
                     /translation="MPCYLEQRVSVQLNVADFPLLIAAGTSLGWEHAINGGVLVFTTQ
                     QNQRITIAKGQATLEQRHETLITELKQAYAQTIIQTAAEQFGWTLERVEGAAQELRLT
                     RFS"
     gene            complement(15294..16847)
                     /locus_tag="PK063_06420"
     CDS             complement(15294..16847)
                     /locus_tag="PK063_06420"
                     /inference="COORDINATES: protein motif:HMM:NF012234.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HMZ96716.1"
                     /translation="MSEQYPLALDFRTARNVSVPLIAVNSLDPAATMRALAWSLVNVA
                     SASQAETDNEFGLHAFPILKWDIGHGLLPLNEEGKNWHAQYVGPSKQNTTINPAEALR
                     LLEKVPERALTFILNGHRYLSNDFFIQGLWNCRDLYKANGNTIVLLGIGFKLPPELAS
                     DVVLLNEPLPTAAQLESIIKEQLSAASLPVPDPATLGKAVDATLGLGAFTAEQEVARS
                     MQASGLNIDKLWDRKRQVIDATPGLSVWRGGNSYAQIGGVATIKRFLKQVLVSKRAPR
                     CIVWLDEIEKSLSGSTGQASDTSGVSQALLGILLSYMQDHQASGLLLVGPNGTSKSAI
                     AKATGAEANIPTIALDISGLKSSLVGSSEQQMRQALNVISAISQDKACFIATSNNISQ
                     LPPELIRRFGYGTWYVDLPSQDEREAIWTIYLAKFGLATDADRPSDHNWTGAEIERCA
                     RLSWELSIPLSEAAKYIVPTAISAKESIKALETQAHQTYLSANRDGVFDQNRDTPHHT
                     RPRTITLAQ"
     gene            complement(16939..17160)
                     /locus_tag="PK063_06425"
     CDS             complement(16939..17160)
                     /locus_tag="PK063_06425"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96717.1"
                     /translation="MSAPQPIPPHTTWLQRFKRLAQLTASLHPEDPRFPIVMRLLEKC
                     DGYYRTDNHASFIETGKRIRSLMDTPPIG"
     gene            complement(17204..17905)
                     /locus_tag="PK063_06430"
     CDS             complement(17204..17905)
                     /locus_tag="PK063_06430"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96718.1"
                     /translation="MKIPLHHSSDTQDVADADQALASHTVAIGRGTHRSLPNRRTGYT
                     QKATIGGHKLYIRTGEYEDGTLGEIFLDMHKEGAAFRSLMNCFAIAISLGLQYGVPLE
                     EFVESFTLMRFEPNGPVSGHAQIKMSSSILDYIMRDLAINYLDRQDLAHVQVTHDDLR
                     GDSVKPYAKSTSRHTPQPLSRAETAAPPTTLGLEEARIKGYEGDPCPECHQFTLVRRG
                     TCRTCSTCGSSKGCS"
     gene            18068..19477
                     /locus_tag="PK063_06435"
     CDS             18068..19477
                     /locus_tag="PK063_06435"
                     /inference="COORDINATES: protein motif:HMM:NF024108.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="HMZ96719.1"
                     /translation="MSEQGIEQLRARNRGGHRDPIVDGKVLVGYGACLQDPQRREGYL
                     VIRDEDRSGHVGILGTTRIGKTRLMESIVEQDIRSHKSVVAIDPKGDIDLFSKVVQVA
                     AEAGRLDEVMLVTPIFPDYSNYLDPLANYYMEDELVSHIVSGIKVKDDYYLSIASEVS
                     QVIVSGLIKLATSRGQVPTISFNDVNQRVGYTELINFRDVLKVLNDTEELCGLIDRVC
                     HGPGIAEHFAKVSSSLRTMLSALTFGNIGRIIGKARTNEFITRLEQGKRVILVCHTGS
                     LLSPRASLIFGRVFVSMIQSLVGRLFASGRQLDPPLCVHIDEGHNVLYPGIQEIFNKA
                     GGANVWLHFYEQSGAQMSAEIGADLARSISDNINSWIYFRVNHAETAQSVEDASPLVQ
                     RPRSVVSVQGNVTLHLNEERLVLRDRVLHLPKRCFYMRTHGQWYKGKTLDSSAPYVQV
                     KFPTPAVNSPKSETPPSAA"
     gene            complement(19446..20561)
                     /locus_tag="PK063_06440"
     CDS             complement(19446..20561)
                     /locus_tag="PK063_06440"
                     /inference="COORDINATES: protein motif:HMM:NF024790.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HMZ96720.1"
                     /translation="MTFRIANFHVRLHYTWLIGFGLITWSLAANYFHDTQADLPVSYQ
                     WASGAIATLLILVSVFLHELAHAVTARRLGYAVKTIELHILGGWTIFERELSSPRVEI
                     LVAIAGPGCSFLLTLLLYAMKADPLANFLYKVNLTLGAYNLFIPCLPMDGGRILRAVL
                     WTQTHSFAVATERTAQMSKQISSGMMAIGILGIIFQYQTLWLAIIGGILRMIAETAYR
                     TVQQSEQLTRPLQEVMIPWDRVVTLVHDTPLLELQDQFLRYGYRAYPTAEHGRITGLV
                     YYKDVRTDPKWLAPNGATITPFIRALSPDVIVHPTHTLQRALDAMLLSGSDQLLVFAG
                     NTCVGMVTRSMIARVQDAIGNPDSGPTLTRQREGFPI"
     gene            complement(20564..21154)
                     /locus_tag="PK063_06445"
     CDS             complement(20564..21154)
                     /locus_tag="PK063_06445"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96721.1"
                     /translation="MKPPSTFRFEFRTQCERKDRPFVARVTWDTEAKSLARGFYAIQI
                     TPVGRFGAVGECTFDAAIGDIVEVKRGETKDREYRGFYLVVPRGYLILVAIADEVDDA
                     LKVVQYVAGQASPQDLAKGHWRFESAESSWKGRPAPIDQTRMEPHPPRPVAQLAPPDK
                     RPAKPTREPAAPTSRSSTTRSVTRISRHTPPLNKDE"
     gene            complement(21154..23265)
                     /locus_tag="PK063_06450"
     CDS             complement(21154..23265)
                     /locus_tag="PK063_06450"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: protein motif:HMM:NF024754.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HMZ96722.1"
                     /translation="MSAYDTNTTSVFPLPLDPPLPAEEPSEPSPLPLSPRKLPDWLHA
                     HIHTPNDLTQERHSAVELNLATISPLIQNAQLNPEQLAVVTAPAEPTLVLAGAGSGKT
                     HTLIHRVAHLVTQGLPPDQILLITFTRKAAEEMIHRTQLLLQQHSLKIQGGTFHAMGL
                     IWLKHYGGALGLPPKFSIMDEDDAQGLVHLLMSKLSFSRRKGFPKKQHILALFSRAVN
                     TLRSIADTVSRDFPWLDAHTPQLVVLFRAYTETKWRQHRVDYDDLLYLVYKLLCLHEP
                     SRRRLGTHYQAVLVDEYQDTTKLQSEIVRLLGSHHHNVMVVGDDAQSIYGFRGAHTKN
                     MLEFQDAFPSVRLYKLEHNYRSTAPILTLANTVLQDAKDLYPKRLFTAKAGGQSPELI
                     ACYSEQAQSDLLTERILQCHDEGIPLHRMAVLFRSSAHSNNLELTLARHKLAFVKYGG
                     LQLTETAHFKDVLAYLRAADNPLDSNAWHRLLLLLDRVGPKLAERIIATMQEAPHPLD
                     VLDQVPGKAESTIRLLNNVIRTTQDESISLTDRLTFVIKHYEPILKRDYPEDAKVRIE
                     DLKPLCDLARQSTSLAAFLEDLTLNPSATSSSKHAHPDHHLVLSTIHSAKGLEWDVVF
                     VIWVLDGQFPPVRSWHEEQALEEERRLLYVAITRPREQLFLTYPTEHYHNASKQNLDS
                     LCRFLAPIPDDILPSYEMDQA"
     gene            complement(23533..24162)
                     /locus_tag="PK063_06455"
     CDS             complement(23533..24162)
                     /locus_tag="PK063_06455"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96723.1"
                     /translation="MQCSSPESFNSVDQAHSADDHRSALRTTLSKIALYNFAAEHRLD
                     TPIELAERLILCVSLANEDRPLTRLELRQITMINPFTIDSALINLVQREEIHMLSQRT
                     SEQAVYGLTPLGHTVTVSLDSWTTSFYQYARCGSVAGVRDLVHQLQQAIRNMIATDSL
                     PIIRTCIACEYFSSAAHALDPQTAGYCRFLRTPLSIQTTKSAAPGIHTP"
     gene            complement(24281..25375)
                     /locus_tag="PK063_06460"
     CDS             complement(24281..25375)
                     /locus_tag="PK063_06460"
                     /inference="COORDINATES: protein motif:HMM:NF014273.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HMZ96724.1"
                     /translation="MQIIMIPTSQIRVHDEYATLFPPLTSSERASLKTSIQEAGIHDP
                     LRVERQPTDAASVQPYVVLGGHHRLSIAQELNIPEVPCIIVTTMELKVAALFDNIHRR
                     QLPDTLRRQMQDEEQRYRARLRERLIPEILDVLPMLPPEVQLQLTQSSHDTQRDFLSK
                     WVAQVQRVGIQPQSEPQHTSPAPVEPEAPDAPIPKQHKQLIRQMNQMTKDFERRIALQ
                     KKELEAVREHNISLSRQLREQSDEKDQLNENLASLQRQLTSENLDHKAERILRLQHKG
                     RRQGPAIEEAGPLIAGLLHTRKTVLVLQTYAQQMTTLTTPDQTTILDHINLTNQALGA
                     IEQVLPRPTDPLQSIPRPSRSVNGDRSADS"
     gene            25374..25559
                     /locus_tag="PK063_06465"
     CDS             25374..25559
                     /locus_tag="PK063_06465"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96725.1"
                     /translation="MPGSLLLAVTSDDSVNVTSGQVVAATMKLPLELMTGDCGLSAKD
                     AISNLLSTGFWLGEVLG"
     gene            complement(25891..26568)
                     /locus_tag="PK063_06470"
     CDS             complement(25891..26568)
                     /locus_tag="PK063_06470"
                     /inference="COORDINATES: protein motif:HMM:NF016430.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor"
                     /protein_id="HMZ96726.1"
                     /translation="MSFRTQAQQLAIDSDNDSPLLKLFQQSKPIIHSIAKRYCNLDRS
                     YEIEDLEQIGFLAVRKATEKWDFSRGNAQFQTFLYRYIQKAYQSEFDGRDKLVEITDK
                     DDQYVKTLPYSTFIKEKRRLHSQGFKSRIFRRLVPLTTHEPPVVPDASAESLAQTDVP
                     GTDDVLGFTATDRFIEFSRKRARAIPDPTALDHDLLTTSEQSITGSSSGSGNHARQAR
                     KRRTYAN"
     gene            26953..27627
                     /locus_tag="PK063_06475"
     CDS             26953..27627
                     /locus_tag="PK063_06475"
                     /inference="COORDINATES: protein motif:HMM:NF024949.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HMZ96727.1"
                     /translation="MVLVKDLLVRMRIAQNLTQTELAEKLGCTASHISIIEGGKSSGR
                     KKILPSDDMLRRIAQCLGGSPLDVQRRTYQLLVARAREVCSPEVAELLDDQILTGMPA
                     AFLERVKQDLSEYSDEELAGVTDQVQLGGRFKQVLSGIGRLSQAEVERLAQVLGQSSE
                     TYLVEAGYLSESARSLFGRNPNCVNILQVFGSLRPETQEELLRFGEASVSLPVSERMH
                     PPTAHE"
     gene            complement(27729..29063)
                     /locus_tag="PK063_06480"
     CDS             complement(27729..29063)
                     /locus_tag="PK063_06480"
                     /inference="COORDINATES: protein motif:HMM:NF039495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96728.1"
                     /translation="MSDAEKPTFIPMNRINGISNRRRMPIIGKIRLGVKVSGPNGFYP
                     KETPHFVVPEEVAKVFGAQPNELEVMFVSNDPTVNCPQALRWYGEAAGLQCIGNNQVA
                     RRLNQDTWKTESRSCPCEKLESGECGPRANLIFMIPKVSSGGLFQIDSSSINSMETIN
                     SYFDFLALTLGRIAMIPLKLRRVPVTRRREGRPTTHYPLELRYEGSADETARYQQETE
                     TVLKKIKMLEIQEPIEINPVLDPGAHVVMEEELEDDPGPVAAEVPGDTPSETHDPTPP
                     AMFTPSTAAAKAPEPTPLPAGPLISVAQTNYLLRLTKALPLTEDDLRMKVRALTQREA
                     SGLIKRLIAQDFSYFTSSPGTPPITPANTGAVAESMTDPQFKKIMGLVISMDIQETHV
                     KSLTSGYTKRQASTLIDQLVGGDFSAFQEMKEEELPVLVTPESAPVEEKVEF"
     gene            complement(29102..30238)
                     /locus_tag="PK063_06485"
     CDS             complement(29102..30238)
                     /locus_tag="PK063_06485"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96729.1"
                     /translation="MLAELIHPLALMEHQEWEYRPRPSNAGPDHCIRKLTYHARHAPA
                     KSPSGRFLVVLDDSSWHEELVLNWISKSTFHLHSQQLELTCATTLFQGRPFPIKGHID
                     GVITDLLGIDRLLELKAIEHFTFTRFAEGNYPINHFVQVVFYLVGLAALNPHIDEALL
                     LIKNKNQSAFLEYRVRYDRDNDRLTVLEITHSTGARIYPKQDFVGLYQEALRRFEEVE
                     QYRDHGTLPARPYPNADNYHCDYCPYQFCWEGIEQVPVEGIAELRTELVPAVEEYLGL
                     QTELAALTPKQKRLDALKQQFKLELKTEGITRAEGHGYYIASSPYEQSKLDQSKLSKA
                     VIERATVKESYSRFSAGRLSKGIDTTKSKRRSPLKKPKPTTQIA"
     gene            30398..32185
                     /locus_tag="PK063_06490"
     CDS             30398..32185
                     /locus_tag="PK063_06490"
                     /inference="COORDINATES: protein motif:HMM:NF024991.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HMZ96730.1"
                     /translation="MNGYGSIQGSMQGKDVSAKVASCPEEMPQVVGVITSRTRARRGA
                     GDWIEIGRKHRAFVPDGIPVPSVGEVGECWGRMTANGADPVLMVSRIRSRRFEACASP
                     SELLGVLGVRRTPPLRFEEVCQLLGPLVEWLCCAGWKAVARGIVKGTLRSARAISADP
                     FLLYRRRRLPFQATVAAAQVLGHELCSDGHYKAAVMEVLARADEEGVGGISEAHLVAR
                     CAELIGLPADKVAPSVSIQMGLVGKFEQGLWFSPVVYFARKKALAMIRANQQDSGDAR
                     SSVQARSLRYRYSIVTGGAGSGKTELAKSLMTQVREQGGKVAATAMTGKAATLLGEDA
                     TTLHKLLGYGGGGYSVSTVDADLVLVDEAGMLTWHTLYRLLLACRGQVVLIGDPQQLA
                     PVGATPVMAELLTVLPVVRLGEEGSKGSLLVKVQVIRFASEALLLYQLRKIVRGYQDT
                     GVEWQALSPVYAGGLGVDRLNRWLQEIMNPDGPPCHGGFRTGDRVIVTKTRYDIGQRA
                     VNGEQGRVLGSMGDTIALRLDSGREVALRAEELRLSYCITVHKAQGSRYERVVFIIPE
                     RECGAFAVEERMQYVGRTRGREATVCMVY"
     gene            32383..32781
                     /locus_tag="PK063_06495"
     CDS             32383..32781
                     /locus_tag="PK063_06495"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96731.1"
                     /translation="MRSSGQEPLVQRAEQCARSITYVAGELIRERFLLGGIVAEALER
                     SQYGDAVIVKIAYRMSTAVGKCIRPHMLYESARIYSAFGGQWERIEALRTGSDCVNRG
                     VPGAHVTTVLQQSVAQPVLESFLGVSSPVF"
     gene            complement(32914..33234)
                     /locus_tag="PK063_06500"
     CDS             complement(32914..33234)
                     /locus_tag="PK063_06500"
                     /inference="COORDINATES: protein motif:HMM:NF025120.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HMZ96732.1"
                     /translation="MTKTIHSFKSVWDALADTPEQAANLRARAALMRQITKVIETNGW
                     TQAEAGATCGVTQPRMNDLLRGRISRFSLDALVNMAAALGRPVRVELQPPKHRRVTRT
                     RRLA"
     gene            complement(33227..33556)
                     /locus_tag="PK063_06505"
     CDS             complement(33227..33556)
                     /locus_tag="PK063_06505"
                     /inference="COORDINATES: protein motif:HMM:NF017757.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HMZ96733.1"
                     /translation="MKPLRFLGNSLERLRQFPEDARHDVGYQLEQVQHGKQPTDFKPM
                     PSVGKGVEELRVWDDSGTYRVLYVARFADAVYVLHAFQKKSRATSARDLEQARTRYAE
                     LKRGKHD"
     gene            33947..34792
                     /locus_tag="PK063_06510"
     CDS             33947..34792
                     /locus_tag="PK063_06510"
                     /inference="COORDINATES: protein motif:HMM:NF012894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HMZ96734.1"
                     /translation="MTGGRPTYMSWAGLACVGLLTVGGCTTRPAVPPTMSDPTRLCGQ
                     GYTFPTTVVSVQSGPQWLLSRPMGCPEPTPLTQVPNKPTVADLPPKPIKAGIHRLQGL
                     PTFSSGTLAARPGDMSRAPGSSPDKAVIPGPTGSPTTVVCRREPEVRHRRVSFAMGSA
                     DLSERAQRDLTELRIEEILYLRVEGYTDPTGSRETNQELGMARAEAVAKVLQARVKGP
                     VQVEVVGRGGCCFLPNHAESRRVEVMMLLQGRCADSSEVERRSEAPPVTPVVSAGATH
                     DSGKP"
     gene            34905..35225
                     /locus_tag="PK063_06515"
     CDS             34905..35225
                     /locus_tag="PK063_06515"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96735.1"
                     /translation="MGDGLRKVAGDIWRMSLLLGLMVLASFVVLAVPAFAGADATFGP
                     LVTLLTNYMQGSLGTLLALVAGAIGLGSAMAGRWAGMFTGFGVAAAAFYIPNIIPTIT
                     TGLM"
     gene            35304..35585
                     /gene="traL"
                     /locus_tag="PK063_06520"
     CDS             35304..35585
                     /gene="traL"
                     /locus_tag="PK063_06520"
                     /inference="COORDINATES: protein motif:HMM:NF018836.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraL"
                     /protein_id="HMZ96736.1"
                     /translation="MNGTFIPRYLDSLPQIFWWEIDELAVLFVCIFLGIVTKFLTYLI
                     VVGIVSTLVLSKMKNGKSEGFLFHWAYWSGVPTFQLTGAPHGTTREMME"
     gene            35591..36172
                     /locus_tag="PK063_06525"
     CDS             35591..36172
                     /locus_tag="PK063_06525"
                     /inference="COORDINATES: protein motif:HMM:NF017152.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraE/TraK family type IV conjugative transfer
                     system protein"
                     /protein_id="HMZ96737.1"
                     /translation="MTIELWKSKLHNAQVLNLVFAALAIVLAVALVVNGFFRQNVAVH
                     VVPINPTQEYWANAMGGDEYYKKSIAMAMLPWIANVTPASVDFHHRQLLQWVPSSHYG
                     LMSESLGAEAVYVKTNNLSRVFFVTASRVDGDMAVFEGIERRFVGKSEIREEEREYRI
                     SMRWEQGRPWVVGLSAVHLDRSLQDGQSDPAKG"
     gene            36183..36956
                     /locus_tag="PK063_06530"
     CDS             36183..36956
                     /locus_tag="PK063_06530"
                     /inference="COORDINATES: protein motif:HMM:NF018311.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system secretin
                     TraK"
                     /protein_id="HMZ96738.1"
                     /translation="MTSSVYRDTKHRAMAMCVLGLLLCLSRAGSAGAAVVVGDEGSTP
                     LTLSGRDLNVLTFPAPITMATSSRADLKAKPEGRNLIVQVKTGPADLVVMAGEQTYVF
                     EVVVSASLGAQTVNIEDRRAGTVPYDSDPARQAGDYVDGLLDTLQMAARGALPKGYRQ
                     TTMNEERYPKWLELKVVQGVEYRGPKYRVIVYRLVNTSGQKYTLREQEFLTGTQKAIA
                     LNREVVESGEEVVVYLLDDAPSEPPKPKPEQKVDPDAKG"
     gene            36977..38263
                     /locus_tag="PK063_06535"
     CDS             36977..38263
                     /locus_tag="PK063_06535"
                     /inference="COORDINATES: protein motif:HMM:NF015688.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbI/VirB10 family protein"
                     /protein_id="HMZ96739.1"
                     /translation="MASIKPTESAILNPGDPIRPEKPAPSKLLAGVVLVGGFIVLSMV
                     LQQFRGNQPGIVRGKSPVKAVSINREATDKEIYMKDAGARIEALEQQRDQMRRLLEQD
                     GRDKTEMKTQLSDLQKRIESVARSGGGALAGTKSGALPPLPPPLSANPLGGASATPVS
                     TMPAPKGPIPVQSAPKPTGGALPAPGVAGGATEAFQVFRPETVPGAKKHEKKLWLNTG
                     TIIPVKLLSGMDAPARSTGAQGGGAAVNSPYPVLMMVRDIMKLPNEARIDAKDCFLVG
                     EGLGDLSSERVMIRGNAISCVKKNGEAVDIELKGFVSGEDGKQGMRGRVVLKEGALLG
                     RTLLAGFVSGISRAFMPYQSGFFVAQSPSQAFNLPPAGPVAMSGMAGGAGRAAELLAR
                     HYSMMAASIFPVIEIDAQREVDFIVGTGRELEGFFQ"
     gene            38285..39061
                     /locus_tag="PK063_06540"
     CDS             38285..39061
                     /locus_tag="PK063_06540"
                     /inference="COORDINATES: protein motif:HMM:NF024498.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbC family protein"
                     /protein_id="HMZ96740.1"
                     /translation="MKQSYQQLMAGMLCAICVSVVCEPDLRAEPDDTVMPIKTVIEQK
                     FPGMKVLRVSKMEIPGWLLVESDSDRVENFMYVHDSGRYVLSGALFDIEMGRNVTQEH
                     VRDRQQALLAGMDASKTILLSPMQPKLDRPLLVFDDPDCRFCQQFHPEVQKLVEAGVP
                     VAVVLYPLVRTHPDAYRKSVAIWCASDQAEALGRALMSKPVVGEAGSCSHPIDDNIKL
                     GKRLGVHSTPMVFLPNGQSFAGYRPASEVLALLQLEMEQK"
     gene            39173..39835
                     /locus_tag="PK063_06545"
     CDS             39173..39835
                     /locus_tag="PK063_06545"
                     /inference="COORDINATES: protein motif:HMM:NF021212.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraV family lipoprotein"
                     /protein_id="HMZ96741.1"
                     /translation="MSLCVLFAGCGGYESNFSCKGYPDQATCESVSEAYEKRFAAGQK
                     VTQYTKDQKDASHDTSGNSGPGQAPSPMVFSGKPDSAVGKPVITPASALRVTVFPWKD
                     TKKRLHDQSRHYLIVDEPDFIFGHMTQGVSPGSSSWHGKDLYPRMGRMVEKRDGKRNS
                     SGNAAVNAMTENIPEAGQRAAPMPVNPLGSGGIMPQGFPQLPQSGGAANYLTDDGQLP
                     PQ"
     gene            39860..42373
                     /gene="traC"
                     /locus_tag="PK063_06550"
     CDS             39860..42373
                     /gene="traC"
                     /locus_tag="PK063_06550"
                     /inference="COORDINATES: protein motif:HMM:TIGR02746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein TraC"
                     /protein_id="HMZ96742.1"
                     /translation="MSTILEWKAKQLVERTAISDWLPYEAWDDTNQVYRLDDGRIGVV
                     FASKPLLGLSEESIQKLTNLFESDLPIGTAFQFMLHASPIIEPYLDHHVVLAQRGQAG
                     ERYVADARKTAEFYLHARDTQLTSNPPLRPRDFTVYVSVAFPTQETTAQGWEDERIHQ
                     AVSGIEGQLNTLGLLPERVGPLQLLNVLHVLLNPGHSWESRPPAYSDQLPIRDQAVRL
                     DTAATLRTKMIELDGKFLKTLTVQSWPVQWHGGNNRELIGSLVRFTDQITCPFFLTLN
                     VLKFDQGKAKGKLRKKHVVINQQASGFLLGLIPSLRFKLDHFNGVQAQLENGRQLIGS
                     YFQVVLYGDTPRHVEEQTGTLRALYRAKDITLQEDHFIGWKIFMTGLPLGLPSDDKAL
                     IDGLRRMKTYHTEVPAHICPIVADWKGGGAPVVLLTSRSGQLITMDVFANQQTNYNMA
                     IAATSGAGKSFFMNNWIKSYLGIGGQVWVIDAGFSYVKLVELLKGQYIQYGANAQRLC
                     FNPFSKLVHWGSSAGGDDDPSDRADELATLKALHAQMASPSRPLSDVELSFIEEAIMR
                     VLEVEGREGCPDSVHRVLRGMTDPRARDLARVLASYAKGGMYSHLFNGTNNVNFENDF
                     VVLELDGLNEQKQLRSVILLQMQMNIQAVMYKKENRGRRKFVILDEAWDLLSQGGNTA
                     AFFETGARRVRKSGGSMITITQGINDYYDKMRDVGRYLLENAEFVGLLKQKTESIAAF
                     RNNGRIVLSEMEYRLLSSVTKTTEYSEIFMITPFGRGICRLTVPRETQLLFTTNPDEL
                     ALIDRVRKEGPKELSIDEAIQCIIAAERAQAGADNPRVA"
     gene            42303..42881
                     /gene="lepB"
                     /locus_tag="PK063_06555"
     CDS             42303..42881
                     /gene="lepB"
                     /locus_tag="PK063_06555"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: protein motif:HMM:NF021981.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HMZ96743.1"
                     /translation="MKPFNALSLLNVLKRAPTILEWLDRHRWVHVGLMLFCGTIIAAG
                     VIAPWYEVAARMSGSWPHHNFFLIQKGQSVGRGSLVAFIMQQDYAERVQPGRLHRDYA
                     DVGKRWMKRIVGVPGDHILVQDNEVYINGQSVGRGIGIDRYGQRIDLATLPETIPEGQ
                     YYVALPHPRSFDSRYYGLIRQADILGTVTPLI"
     gene            42927..44123
                     /locus_tag="PK063_06560"
     CDS             42927..44123
                     /locus_tag="PK063_06560"
                     /inference="COORDINATES: protein motif:HMM:NF021209.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC family F-type conjugative pilus assembly
                     protein"
                     /protein_id="HMZ96744.1"
                     /translation="MKGSSVIACMAVTVVLSLLSIGSPALSESTGRPSKPSPEEMAQD
                     IARYSRQALRQGRPQESPKEMRRDGLYLLLSFSLPDDTLKDYLREAKLLGAKVLLRGL
                     VQESFKVTQDRIKRVLFTGERPDDSLLVGIGIDPVIYRTVGAGEVPALVFVKDEKFMV
                     ASGASSVAHLLALLSQEQARLKPWGEWFERRHRGFLQGGPTEEAPPLLPTIERSVKVW
                     ADARGADIAERDMIDVMKERVANANWPDIQRRSGDALKRHFAKGPGLALPHVEEARVA
                     FVDPTVEYPEDIKDPTTGTVLIKSGTKINPFDKVRWIRTLVFFDGTSPAQMGWVQQYL
                     REHDPKFVKLIISDGDVQKVMEQLHQRVYWANPLLVSRMGVGAVPSVVSQLGRNLRVE
                     EVAIHD"
     gene            44116..45204
                     /locus_tag="PK063_06565"
     CDS             44116..45204
                     /locus_tag="PK063_06565"
                     /inference="COORDINATES: protein motif:HMM:NF018536.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraU family protein"
                     /protein_id="HMZ96745.1"
                     /translation="MTRSSMRGIRQVFLLVCLSCVLIGVATLWPSGTAEAVCTIGNPV
                     LANSLATTCWECMFPISLSGVTLFNPGEDFTAPAVGPGRAPFPPQLCGCVCLGPICIP
                     GLPLGIWEPKNLVEAVHDPLCFPTLGVSLAGGFSYIGRGMATTQMDSELNYAFFHVHY
                     FIFPLWAIVGIGLDIACLNPTGIADEIDLAYASEIDPLWDDDLISLILFPEALVLANP
                     VSLAACAADSVAAAVGFPIDPLFWCAGSFGFMYPPTGHVSGADGDLKPAALSMTRLLA
                     KLARAGTEFWTSANGPLLCDDVTTALIVKSQYKFQLLWPIPNTGIPPPCCQPLGRTLM
                     MWGLGKIVPAVGEDFVWLLWKRQNCCLL"
     gene            45216..46076
                     /locus_tag="PK063_06570"
     CDS             45216..46076
                     /locus_tag="PK063_06570"
                     /inference="COORDINATES: protein motif:HMM:NF025105.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
                     /protein_id="HMZ96746.1"
                     /translation="MSVCSMGGPTGVARAADPPGSKTFIDHPRQGWFFYQDPPAEAEE
                     DAEESPVSVTIDGLPPGAWLEPSKYRTWFKGLAMDGVKLTALPVTVLRELVSAKKERA
                     LDDPSVENVTSYIKVQKEAYDRSQRFTDAWQIAMYTDPKLDYASQHPTSTYGHSVESE
                     IKRNTEEQLLAGTADRVGLFFFFTSTCPFCQEQSKVLKVFADTYGLTVKPVSLDGVGL
                     PEYPQPAINNGMAENVGVHMVPMIYLAIPEENFLKPLGAGLMTNADLRERLLVLLRNR
                     GLLGERPSHG"
     gene            46087..47421
                     /locus_tag="PK063_06575"
     CDS             46087..47421
                     /locus_tag="PK063_06575"
                     /inference="COORDINATES: protein motif:HMM:NF017892.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraH"
                     /protein_id="HMZ96747.1"
                     /translation="MRCKRILVGLCMWAVLAWPPLVQAQSMNDALTNMFSSWGVGITS
                     PPGAYESQRRGYFSGGGVSVRLWQDPMRLWSIAPPRLSVGCQGIDVYLGSFSYGKLDR
                     YVQLLQQIGTGAVLGYAFQLAMKAICEDCADVLNKIEAAARALNAAGRIQPCQTGIEL
                     GKALAGNEASKQKLASRFGDAWQKMKEAGGAIGDVFEDRDAVKNQSNADAASALKGTE
                     YDVTGNLVWDVLTQAGLDQNLIVMVMSVTGTIIVGNDGDVQTRDPTMTFEQLVDSHLG
                     DVVKIFNCGGDSECLNPTITDATDIEGFESRVYTSMSNLIEDLYSGSAISAADQQIIN
                     MTPVPILTMLADYGRPRDVGNQIARLSSEVVAADMGYQWVKWAASETSRNVSYIQKVK
                     PEWPGNLQDFQGRLHQVLRGASDSLAKRQRMVNNINQLMQLTKTQGEMRSLR"
     gene            47470..51936
                     /locus_tag="PK063_06580"
     CDS             47470..51936
                     /locus_tag="PK063_06580"
                     /inference="COORDINATES: protein motif:HMM:NF019530.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraG N-terminal
                     domain-containing protein"
                     /protein_id="HMZ96748.1"
                     /translation="MWTIYTFGNGDVLTQILLGIRIMMTTGRFESLMELALLVFAMFG
                     LVYFVFNRRFLVPLVVGAFFILFVSVRITVDVSVEDQVNPDVPDQIVNNVPLAIALPA
                     YISGQVGYYTTQLVEASFPMPVQYTQGQTSFNRPLFDLQKVLNARLQDSDLARNTDTY
                     FMMCVFREVGLLQKNLGTLRNSPNLLNDVGAMNNALTALGYTGGTLEAAPRVCPDFYS
                     SLILPGYTSGQPDYEGAMRHLRTQLQLDPATGNEEGLTEDIRANLLLSVGQSARDMIN
                     NVLLIHAWKNAESADAKRRAATADTVLLQQEAIQKDLKFQSYSKSYVAQKVVPLLRTI
                     VEGVVYIMTPFLLVLAISPGMSRLMGTYWRLFMWLQTWSPLYAVLNFVMFWEARSRLG
                     AILSSNGVGQSVNYATLDRINEHVAMLNSTAADYVWLVPAIGFGLMWGGSQVLGSILA
                     GSRTAETVAGQVGGQFSRGLGANLEEGPSYRHEQRGAQFGEMIGHDVEPQMTVPAGPG
                     GFRVDSQSGTSEIHDSQGGITSIGANGIQNYKGPEGQYAMDSKGHLLSGVFRHKMTDP
                     QSGKQVDAQTSVFGSMVEHRFDTMGEDGARKSVLVQENQDTGELVARTEQSVRKGLSE
                     TRTIADDGSQSFSRSGNVPLFLEVAGETRPDAGFVQMMGERGPGERADTITQSMFQST
                     MGAKQSYTGRLVERDGQFHFLATEGGAIRGFDNKDTEAAVHRESFVSPDGSNYFVETG
                     QAQQMVLGKDGVTRPMEGYVRAFGSVDRSDPAHPRDIYSSYSLTSDEGGHTHTVTGTL
                     GTDASGRQFLVEATEHFESGTSGVAHDTQTVGSYTLSGTFTALSHGEANQPGVPTAFF
                     GSAIDNSKPGSPAFQANALLYDGQVSFFDGREGGTKSISGERNLTDGTHLSGQFTQLN
                     TMGQDGHQIEMFHGYAQQPGAPARDVTGLIDNGNLVAFNGTSGSHARDIVEKGSGVSG
                     RQYGFQDTLMAPGGTHSVSTFEGVSVDAQGRAFKNSSVELDGVRVYSDQMRGSRQMTV
                     EFEQSLRGYNDEVQSIDKESGWRRINDGHRDMDVYANLYYGPTSSETGERKLLGGTIT
                     NVTDNTYSTFMKDGEGNEVWGIARSLEDPNSEAMSGSFDQTLKVVAAKNGAVDTQVLG
                     PMKSDGGQREVLYHSVLGGLDSQYFNNERKSGVFTVPDPMHPGQTKELQGTFYYSPQS
                     GQLIASEVTDVQTGKVGQYRTDAQGQEHFQVVEYTQSPDGASVIASTRELSKHEYAAH
                     GFAVNDTLDSSGNVLSSSGNKGADFHDFNRVQFHHDSGANLTITQMAFAAKGTDITNP
                     TQTDEAIAYGLEFGRIGMDGASRYLILKGRMGKFGGGAAGGTPFQSGGGPLPDGPGGG
                     GGPSGLLDSHQNMGAWWKEYSGVMDNAISFARSSVEHLEKTGRAQTMSPEELQNFAAN
                     AAYNAVRTSAIGMLGEEASNAFGTMPKWQVGQESLLKVERTQPSAPSTSKEK"
     gene            complement(52371..52559)
                     /locus_tag="PK063_06585"
     CDS             complement(52371..52559)
                     /locus_tag="PK063_06585"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96749.1"
                     /translation="MALTIRSGAADQETAILEFVDIQKAERIRYDVLHFSRDWTEDAR
                     MFKDYLQTIFHAKYQSCS"
     gene            52640..52906
                     /locus_tag="PK063_06590"
     CDS             52640..52906
                     /locus_tag="PK063_06590"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96750.1"
                     /translation="MTPTVHPKPSLWSDGATRGGSTAVVEVMSRDSLNVCNVVGVKTG
                     AQDTPVTNPSRITLIVRQDDSDVSATRARTFSLDDSRSGRGLFR"
     gene            53027..53656
                     /locus_tag="PK063_06595"
     CDS             53027..53656
                     /locus_tag="PK063_06595"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96751.1"
                     /translation="MARVIRMDPGHSAYLLWADSIGRYAILPHQHADRQYKVRDSLMG
                     AVYKVGDEFPMLSQRSMHYFRRIAELVLAPVLADDHVHIKRVATSRAASFVKVAVDTY
                     RSGEDVIAACKPLLYEFRTYTSRTIALVKYHSELESYIREALAPAPSRSVRRVDVYRE
                     EHQARVIVEPGTIAQFLGRKGMNAAVASKLTGYGLVLVDEGDLGKVGGA"
     gene            53672..54343
                     /locus_tag="PK063_06600"
     CDS             53672..54343
                     /locus_tag="PK063_06600"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96752.1"
                     /translation="MAHGVDVEQQPGMVRREGPSLRSASPTNGRRPDRAEENRKRMED
                     PNSILLLPQTKAGMACVSLLYMFDKVVHRLRRAAGSQLSVEQVRNELARVEQWVARAK
                     GLLRELGVGEFELLPQELYPDLKERSVMAARRNARVITPRVGDTVRLVPVIRALDSAL
                     NSIRLRAEDLSPYVKHFQAVDELVVALHDVIGHVARVTVTEYEPRGAVKAFLQEGKES
                     QSTLS"
     gene            54358..55335
                     /locus_tag="PK063_06605"
     CDS             54358..55335
                     /locus_tag="PK063_06605"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96753.1"
                     /translation="MWPRMAVVGLAVLSGCVSAGEYQDLETKYQHQLAVKEVMETEHD
                     ELSHRVDNVSQVYRHVAQEQMGLKAQAETLQGEILTVKGVVKDTQSQYEAQRAQFAQQ
                     TQQLSGVDARLQNIAGKIETLTETTVALANRFERVELSIGKLGKSLQARGGAPEVSKT
                     RVQVGEGKSGGAQKADPVAKAGSPNMEGSAGAGAVGSGSEPGGTSLAAAPSPVAPTTA
                     PAKPDVPMVVSPKVVEAKFEPAGSKPDADKGWLRRFLDGFRGGNGQVAEPVSTPPTAG
                     SVGKASPGRPLPPSVDGEVMAAPMNTLTISTEGDAPKKAEVSPIDTEKR"
     gene            55342..55833
                     /locus_tag="PK063_06610"
     CDS             55342..55833
                     /locus_tag="PK063_06610"
                     /inference="COORDINATES: protein motif:HMM:NF014019.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HMZ96754.1"
                     /translation="MKILTVDVIPGHAYRYFQALIQIETVGIASWRDAVVRFTDFWGG
                     RAKTYDSPIVHATQSMVDRLAQSAASLGADLIIGFDIQIHQVTARYWGWGMAQIVMRG
                     TPIQFTDRHAMGTIFAGESAPFVASGEPPQHPADGNFQGEAAGMAEMPVPSLDTARFG
                     TRV"
     gene            56218..>56724
                     /gene="traN"
                     /locus_tag="PK063_06615"
     CDS             56218..>56724
                     /gene="traN"
                     /locus_tag="PK063_06615"
                     /inference="COORDINATES: protein motif:HMM:NF018666.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraN"
                     /protein_id="HMZ96755.1"
                     /translation="MTTAQSAAETLPPDSITCGSQNSSVPFCVDTNTPPNQNLALAAT
                     WLSMTKNVEEDWDPDRLRIFTGKRSTCDFSTIGRSLINCCDSDPDKLIGKCSDEEIAL
                     ARDKQDWKARLIGTHCVDKGPFGVCLRKEEVYCTMKSELGRMVQEQGRAQLGMTWGSA
                     DAPQCDGFT"
BASE COUNT        11871 a        14053 c        18121 g        12679 t
ORIGIN      
        1 actacttcgt caaaggttct cttttatgaa gtagtaggac ggcacttgac tttcgtccat
       61 tagcagacta tacagactta tatatggaca aatgacacga ttacacaaat agcgtcaatc
      121 atgcatggat atcaacggtt tagatgaata ttcctgatca gaatcccgct actggcaggg
      181 ctgaatccgc gcctttttcg tctgccctcc tcagcgaatc cgtgtggtca cccctcgcct
      241 acactggtct tctccacttc ctcttagatg gagggatgac ggcgctctcg gctccaacac
      301 aagtggttta cttgcagctc gttcgagagg ccttcggacg acgacgcaat cctgtggcaa
      361 tgacccttga tcgtctccaa gcgaggacgg gcttgagtcg ctccaccatt caccaagcac
      421 tccaccgctt ggccgatcct gacgtggata tcgtgaatgt tgtccatccg ggaggcggga
      481 agcaccccgg tctctatgag atccacccct gctcctatca aaaagtcttg ggacttagcg
      541 cgaagcgtgt gccagtgcgc cgccggtcta aaacggcccc cccagatggc cggtcgattg
      601 agaacctgct tgcccaattg agcgcggaag atcgggctga tttgcaggtc gtatacgagt
      661 cactacaggc ccatgagcga aaaatgatcg aagaggaggt tcgtgccagg tttcatgata
      721 tcggccagaa tcccgataaa acgacctttc aacaaggcct actcttctat ttgctgaaac
      781 agcgcatgta cggacgcctc cgatccaagt accccaccct gtcctcacca acctaggaac
      841 ttctcagacg atacgagttg cgcccgcgca actcgtaaat attccactag tatcgacctc
      901 acagacaaaa catatttcac catcgtcgcc tgaacctaac aaacatagtt ataatcattc
      961 acttacattc aatttgccta acaatcttta gcagtatatt tacgagcatt attcgcatac
     1021 gcaatatcgg gaaagacccc tccatatccc ttcgtgagtt gcgcccgcgc aaccacaaaa
     1081 cattttacag tgacgcgtcg agatatagtt attatattaa ttagttgaca ggccccacca
     1141 tgaggagtaa tgaaacagtc aattgcggcc caatgtctac aagctaatcc aacacatgtt
     1201 agacaaaacg ccgtggcaaa ttacatgtcc tgagtaggtt ggtttttcct acgctctggt
     1261 atatggccta tacatagtag gccgaggagg tatcgatgcc gaatgtagtg gccgttatca
     1321 atcaaaaagg cggggtggga aaaaccacaa cggtggtgaa ccttgcagct gcgctctctc
     1381 gccttggtca tcccgtttgc gtggtcgata ttgacccaca agcaaatgca tcttcgacac
     1441 ttggaaaggt aagtccatac gaagccagag taactgccgc cacactgatg atggataaca
     1501 aacgcgatga ggacatgacc gcaccctggt atgacaccat agagaaggaa gtccgcctga
     1561 tctatggcca tgtgtccttg accaaagcgg accgagaact tcccagggtt tatccgacga
     1621 tgccatccat cgtcctgaag cgtcgcctgg agcagatggc ctttggggat gaagatatcg
     1681 tcctcatcga ctgcccgccg accctgtcga tcctcacgat caacgcccta gtcgcttcgg
     1741 actactattt gacccctatg atgtctggct caaaatacag catcacggga tacgaagacc
     1801 tcatggagct ggtgcgcgat gtggtggata gcgctaatcc tgccctgaag tgtttgggga
     1861 tcctcgtcac gcaacatgat ggacgaaaaa acgtctgcaa gtccatgcgg ggcgtgatcg
     1921 aacgtcgttt cggagatctt gtgtttaaga ccgcaattcc cctggccgcc aagatccaag
     1981 aatcggaatc gctaaagaag acgatctttc aattagatcg gcagagcaat gctgcacgcg
     2041 agttcatgga tctaggccgc gaggtcttgg ctcgcatggg tttaggtgca ttggcggagc
     2101 ctgacgacat ggatgaaccg gtcgaggtcg gggcaggtga atcatgacga gcaaacaagt
     2161 ctccaaaggc aaagacgaga agccgcctct ctcgaaaagc aaagaggcca aacctgaacg
     2221 ccagaagtcc tcacatctcg ctgatctcga agcctccttt gatcgtgatg ctcgtcgcat
     2281 tcgcccgttt gccctggtcg gtttggatac acaaggtgga cagcccggac cagaacacac
     2341 gacacccccg agccaaatac catcgacaac cttcgactcg gctgttgatg gcagcgcgtc
     2401 cgtctctatc ccgttgggtg ctgaagctac ggcttcgcct gtcggcccca aagcggttcc
     2461 cataatcgcc caagaggcag atcacctgcg tcgcctcgaa gaggtcgtcg aagtcccgct
     2521 cgatcggctg gtaccgagtc ctgaccaacc acgatctgag gtcgatcctg cggctgacca
     2581 ggagctattg gaatcgattc gtgcctatgg cgtgctcacg ccgattcagc tccgtccggt
     2641 agaggatggg aagtacgaag tggtggccgg cgagcggcga tggcgagcct gtgcgttgct
     2701 cggaaagacc tcgattccgg ctctcgttcg tcgaaaggac cgggaccgcg cggcggctga
     2761 ggcgctggtc gacaacgttg tccggaagga tctgtctgcc ctcgaggagg ccagggccta
     2821 tcaagccctg atcgaacggt atggttttca gcagtccgag ttagctgaac gcctgggctg
     2881 tcacaaatca cgtatctcta gggcgctcag catcctgaag ctgccagaga gcatcttaaa
     2941 cgtgttcttc ggacctgaga gccgcatgac ggcgacgcat gcagaggcgc tcctcccttt
     3001 ggcccatgac gagccacgcc ttcacgccat cgctcgccgt gcctcaaaag aatcgtggac
     3061 tcgagatcgg atccgacagg aaatcgatcg caaaccacga attaatgaag gtgcccaagc
     3121 cgtgcggttc gtggagcgtg ggcggggggg agaccgtggg ttcatgctga ccattctctt
     3181 tcattccaac aagccgcatg aaatcccaat tattgaggag gcgctcaaac aggcggcagc
     3241 gcgtatacag gagtttcgtg acaagctgac ctagcgtgag atgttcaatg aaaagtttca
     3301 ttcaacttac gaacggacgg gcggcgttct catccccgtt gggaaggttt tcttccacct
     3361 tcaaatattc cagtcttttt gaagatttac tgtattaccg gatcgggggc gaatatcgat
     3421 gtggtgcgcg atcctagtta tccacagccc tatcgctagt tgagtgaaga tttcgcgtta
     3481 gttcgatgaa ggtctcgcaa gttgaatgaa gaaaccggct ccattttcac gtaagttgaa
     3541 tgaaagccga cgtaagttga atgaagtcac gctacttcga tgaacgacac agtttttata
     3601 aagcattgat tgcgcaacga aaaacaagaa ttaagcgact gataaactgt gtctctacgt
     3661 tagaaactta cgaaagaatt aataaagaac gttacgctga tggacgctga tttcacaccg
     3721 ccttcggaat cggacgaggg gactggttcc tctgacggga ttcccgctga actgatcttc
     3781 cctggaacca ccacggatca cggctctcta tcggtcacca cccccgacca cctcctcagc
     3841 gagcatatct taggatcaat tccactgtgg gaagcgaaag gccgcccaac aggtgcggaa
     3901 cgagcctcgt accaaaaaca gatttatcga gatgtgtggc gtaacagtcg gttatgtaaa
     3961 gtctccctag tggtctacgg cagcggcgat ttagggcttc cgaattcgat tgatctggag
     4021 ttctttcgag ggtttgaacg atggacgaaa gccgcgctga gtaggggaga gccatttaat
     4081 cagttagtaa agatttcagg tcgtgaattg ttggaggcga gcgggaaagg ccttggcggt
     4141 gcctcgtacc aggaaatgga tcggttcttt ctgcgtatgg ccggcacgat gatcggcgcc
     4201 gggcgagatt ggcgacaaga aggcgaatcg gggggaagcg agaaacgtcc tcgttcgaac
     4261 aagggaatcg tctttcatat ttttcaaacg gtggtgttac cggggcaagt caatgcggaa
     4321 ggctatgtgg cggataagta tgaggtcgag cttgccacgt ggtactggat gagcctgagg
     4381 tcgggcaatt gtatcgtcat cgatcatgaa ctctttcggg acctccatgg atcgattaca
     4441 aagctgttgc atcagttact gcacaacctg ttttaccttg ggcgtggaac ggcctcacaa
     4501 aagtattccg agctggtgcg gaattggcag atcaagcggc atagcgctct atcattggta
     4561 aaacagcaat tagacgacgc acatcgcgag ctgctggaaa aggagtttat ttcacgctgg
     4621 gagtatgtgc cgattcgaac gccggagggt aaggagtttg agattatttg ggaggcgggc
     4681 ccggcctggt gggcgacgga caagaagacg cgggagttcc gtgaagagat ggtgggagcc
     4741 aatcaccgcg agttgcaaca gatcggacga gagctggatc cgttcctcct catcgagcaa
     4801 tctgatgaga gcaatcagga gaaggatggg caacgagaag cctcgaatgc gcggctcctg
     4861 agcgtcgtgc tagagatctc cggaaagcgg aaggacccca aggtatggga gaaatggtgg
     4921 aagcgtgcga tcaccagcgt tccccatccg atgatctggc gacgaatcgg ggaagtgaag
     4981 gaacgtcgat tatctggaca gacgatcaac caaggaagtt atctcctcag tctcattcgg
     5041 ggtgatgctg cccggctggg gctcccttgg gccacatccg acaaggttaa gtaactccag
     5101 tctttcgtgc cttcaatcgg tgccggtgag cgagggactg ttggcggact accagtgagc
     5161 gatggggcgc catggagatc gggatgtcct gggaaacggg atccttttgg acaggatgac
     5221 ggtccacata atggtccagg tgaggagact cgtccagtaa gcaagaatgg ggtcatcctt
     5281 aaggattcaa atggtgaaaa acagcatggt ctccagatct gagcggatcg atcattgagc
     5341 gaggcgctgt ctgcgcctcg ctgagagtga gcagtccttg ttttcaaatc ggggcatcag
     5401 aagaggcctg ccaatgaatc ctccagtttg tcgctgagaa tcttgctggc ttccggaacg
     5461 gacagccaca tcttttgatc cgacgccaca attctcgctt gatggaagcg gcgagtgcct
     5521 ttccggatct cgccgatttg ttgagtgacc tgccctgcct gaggcgggga gacactctgc
     5581 tgattcagaa agccgaaggc cccggcttgt gactgtggaa cccctgggcc gggcatgctg
     5641 ttcgtcgtga tggattgttg aatttcttcc ttggtgcgct cctgtaccat cgcgtcgacc
     5701 acgcaggcga cgatagaatc ttctgagagt ttgctcgcgg caaatcctcc gacggctccc
     5761 accgccccga gtatcggaat atggctgagt gaggccccgc tgagcgcggc ggcagatccg
     5821 gctgcgaccc cgatggctcc tccgaatccc ccggcgatca aggcatcgac ggtctgcccc
     5881 ggcttcagtt tattgcagag caccacctgg ctttgaagga tgaactgagc gttgtcgggg
     5941 ttatcaacga ttgcgtaccc cttggctttg attttgttgg ggagttcccc aaagttgata
     6001 ttagggttgt cgctggtatt tcgagtctgg agatagatag tcttcttctc cgacggggtc
     6061 agaaagatgg cgttactgct ggtgagattg acctcatggc ttagcgtcat gtggccagca
     6121 cagccaaaga tcgatccggt ggcaataccc acaacaacaa tgacgaaggc tctgccggct
     6181 gaacagaggg tgcgacggat aatcggtgac atgctttcct cctggattag gtgaacgagt
     6241 ctgaaccgct tctgctatgt attgccggat agcaacagag tgccttttgg gatattaggt
     6301 gggacagcga tcacacagaa tggaccggac ctcaaagatg tttctatttg gaacaactgg
     6361 aaatggagca gtgttctgcg gtaagagatt cgcttgaagt ggacgttgag tattgagtca
     6421 tcgaacgatt gttgccatac tgtgacggtt gaattatgaa gtctgatagc gtggaaatac
     6481 gtattgccgg atgactctct caagtgccac cggcattctc tgacgggaaa tcgcatcgtg
     6541 catcagccaa ctgcggtgtg aggcggtagg cgggaaggta caggtcggca tgtcattagg
     6601 catcaaaggc caagactcga cgtttgatct ccaagaattc tcagtcggcg atgtgtgccg
     6661 tcttgggtcg aagttgcgac gtatagagac agcgggaaga tcgtcagaag agatctcgca
     6721 gtcgatcgcg gagtgtctgg tgcgttcgtt ttattctcac gaacttcgtc gctcgcaact
     6781 gtctcttgtg gaggtgtttc aaacgcgaaa tcttggtgag atcccgatcc accgtcaaga
     6841 gcgatgggta cagacggctg atggggcgca cgcttctgct caaacccgcg ttctcgcatt
     6901 gatgggggtg gctggagact ctgtggaatg gacagtcgga acgcctccgt tcggacgaca
     6961 ttgcatccac cttcaggagg agttcgattc agaagaagca gcgtggtaca cgcaatcgtg
     7021 gaaagagttg ggcctgaaca ggccagtgaa ctatttgggg agcgattgcg tcgttacgga
     7081 ttcacacaat caattgtttg aaattagtgt gcatgaagtt cctgtttcac cgaaactcgg
     7141 aaagagaaca gagcttctgc ggacgcatga ggtgaaacag attgttggcc tggggggacc
     7201 gttgccttct ggagaaagtt actgtgtctt cctctatgcc aatgtgccgc tcgatgcgaa
     7261 aactaagtcc ctgtttcaaa tggtgtcggg gaatatttct ctggcgtgtt cggctggaga
     7321 tgaccagtgg tggagtgctc gggccaagcg tggtgaaggg acgccatatt cgaaggaggc
     7381 tggcttcgcg tttgcccaag ggatctatcg ccgacttctc gagctgaatg agtcgttcgt
     7441 tgtggatcaa gagaagagct attttgagga ggtgcaagag ttacgtcaga gcgatcttaa
     7501 gatgcgacgc atcgcggatg cggtgcctgg tgcggtgtat caatatgtca ttgcgcgaga
     7561 tgggtgccag cggtttagtt acatcagtcg tggggccgtg gacatggtgg ggtatccggc
     7621 ggacctcatt gtttcggact ataacgcggt ctggaaactg gtcctaccag aagatatgcc
     7681 agggatcatg gcgtccattg aagatgcaat tcggcgtgga ttgcggtggg cgcatgagtt
     7741 tcgattgcga ctccccgatg gtcgggtgaa atggttacgc ggagattccc tgccggaggt
     7801 tcctaccgcc gatggaacgg tgctgttcca cggtttgttg accgatgtga ctgagcggcg
     7861 gttggcagaa gccgagctgc ggtttacgca gtttgcgacg gatcatgcgg cggatgccat
     7921 tctttgggtg gggcctgatc gtcgcatcat gtatgtcaat gtgcgagcag ccgagttgtt
     7981 gggctattca cgtgaagagc tcttgaattt gtcggtgccg gatattgcgc cgttgcagag
     8041 ccgaatcgac attcttaacg atctgacacg gctgaaggag ggcgaagtag ttcagtatgc
     8101 gactactttt cggagaaagt ctggagcggt cttccctatc gaagtgtcga tgcgatgctt
     8161 ggaacacgat ggggaggggt atgtgtgtgc gatcgtgcgc gacgtgtcgg agcggaaacg
     8221 tgccgaaagt gtgattcaag agggagcgga ggctctacgt cgtagccaag aagcgttgcg
     8281 tgccctccat tcccaattgc tgaccgcgca agaggacgag cgccgtaggg ttgcccggga
     8341 attgcacgat gatctagggt cgcgcctggg gagtgcaatt ttgaaggctg aagggaaatt
     8401 ggtgttgttg gagaacaaca gttctgaggc cgcggtcctc aagaatgtca ccgatgagct
     8461 gcgaggaatc agcgatcggg tgcgaacgat tgcgcacgga ctgcatccgt cgattctgga
     8521 caatctgggg ctctcggtgg cgctaaagaa gatggtgaaa gagtatggca gttggtcggg
     8581 tatgaaggtt gtcagtaata tctctatgga gtttaccgag gtcttggatc gggaggtcgc
     8641 gacctgtctc tatcgaattg cccaggaagc cttgatgaac gtaaagaaac acgctggtgc
     8701 acagcaggtc atgatagcgt tggcccgaca agacgattgg gtgcagttga gtgtgaaaga
     8761 tgatggaatg gggttcagcc ccgaagcaga atcgcgtcga acgaaaggac tgggtattgt
     8821 cgcgatggaa gagcgtatcc atatggttga aggggaattg acggttcagt caggaaaagg
     8881 gcgaggtgct gtcgtagtgg ctcgggcacc ttacagggag cgtgaagcat gacggctagt
     8941 gtggattcgt cgatgaactc tccggtcaaa ccgataagcg tggttttcgc tgacgatcat
     9001 gcgttggtcg cagatggaat gaccaccatc ttatatggtg tcaaccataa gcagcgagac
     9061 tacgaatttg ccgtggtggg ccaagcgtcc tcaggacgtg ggttgctgga gctcgtgaag
     9121 cgggttcctg cggatttggc gtttgttgat atctcgatgc cggatatgtc gggtcttgat
     9181 gccgtgccaa aggtccggga gatccggccc gacattaaga ttgtcgtcgt gaccatgcat
     9241 agagaacccg aatacatgac ccgagcgtta tctgtggggg caaacgggta tctgatgaag
     9301 agttgcagcg ctcaggagtt ttgtcatgcg atcgatgagg taatgagagg caacgcgtat
     9361 gtgacgagcc tgcttggaag ttggccagga ggcactcttc ctggttctga tgacgaagag
     9421 gatcagctcg cctccctggg gatgtcgcag cggcagcgtg aagtcgtaac gttgttggct
     9481 tcaggcaaga cgatcaaaga aaccgcgttt cagttggggc tgagtcgaaa gaccgttgaa
     9541 caccacaagg cgatgttcag ggataaattc ggcattgata cagacgccga cctgacgaag
     9601 tttgcgatca agcatggtct gaccgggatc gattggatcc ggaagtaact gcgcgaaccg
     9661 atgggggcat tcattcttca ccgcagaatc ggtggcaccg caatcaactt cttttcgctc
     9721 tctgcaacgt cgttcagtgc cgaacacccg cagatctgga tcagtgaatc taggtcaaac
     9781 ccgagatcga ctctgtcaca tcgacttcct tgacgtgtcc ttccatcgta taggctcagg
     9841 tctcgaatgc cattgattag cccgttcccg ggggagaaag aacagcccgc gggatgcttg
     9901 catcgtcgat gcgaagcttc tccagacctt gatgcctact gcttatctcc tgaagttgtc
     9961 cgttggttgg gttgggcagc gtgatgtgag tttttgggca tgacgggttt gacaaagtcc
    10021 acccatcgtt cttccatcct tctctcgatc tcgccaaaca acctcgcggc ctctcgtatt
    10081 tcaacaatac cgccgtactt cagattgaga gacagttctt gaagctgcgc cgatttaatg
    10141 aaataccacg ttgctcgtcc gcggaagtcg actgtttgct gcaacgcagt ggcgagggca
    10201 ggaagggccg ctacgaacgc tgtgaataga gggaaacttt tcccgtctgc gacaagaatg
    10261 gcggcgattg cactggccgc aatggcaccg atcgacaaag ctagatcagt gaggttgttg
    10321 gtccggccgc cagaaaatgc acccgcagca cattcatcaa tttcagtcgc tagttcttgg
    10381 atctccgggt tcgacgccat tcgaatcctc cacgctgaga tttacctcgc ggacaagtat
    10441 aaaggcggca cccattatgc tccttattca tcatggtttg cagttgagcg ttcaccggcg
    10501 gatatgtttc cacgatctga gatcttacga gtggcttcac gtttatgcgc tcttcgatct
    10561 ctcacgcatc gatttcccca gggactaccc gatcctggct aggtgtctcc tgaatgtgtt
    10621 agggcgagac gtggggaatt atgtgcaggc gatggccagt cgtgaggggt attgctggct
    10681 gaatgaggag atgaggcatg ggagtcctga tcattgtggc aggtggtccc gatccactga
    10741 cgccctgcgg ctgcggttgt gttgaagctg gctaacaggt catcccgttt ccatctgaga
    10801 tgcactgtac cttttttgaa gtagcggata cgaaagaagg tactctcgca gtggcgatgg
    10861 cccaccccgt ggttgtgaaa tgagcattct agtgcatccc gtacggtgat aatctcctcg
    10921 aatttgtccc catcaagcac agcgagcacg cgatccaggt cggagtagag ctcgccggcg
    10981 tcacgggtgg accacaggtc gaagcgttca ttccaaaaac gacagccgta gggaaacaca
    11041 agtttgcaat tgaccttgta cgagtcgttg gttttccagc cggacctgcc gtcaccactt
    11101 ccgatgtccc cggtggtatt gcccttgtag tgccgggtga gcgcaacgaa cacgttccag
    11161 acagatcgtt cgaagagtcg tttgcgctgt agaaaaatgt tcgtgagggt gcccttgatg
    11221 ttttttgctg taaaggggac ggtactgtct cgctccaggt cttgtaagag ttcctgggtc
    11281 tgcttcgtat ccagccactt ctgaaagtcc atttgtttaa acacgtgcat ccaggcgctt
    11341 cgtcgaaggg cccgtgcgaa ttcggcgcgt gcggcggtgg tgttggtttg tgccatgccc
    11401 aggatctttt tgagatcggc ttcgtcccgt attgagctgc cggggagaag cttggtcccg
    11461 agcgcttgca taaatagact ggctttgcgg atatgggcga aggccttaaa catctcctcc
    11521 agggagtgtg tgtaatagtg ctgcatatta ccaagcgtgt cgcggagcgc ggggatcgcc
    11581 tcaggggtgc cgatgtcgtc gttaatagat tgttcgcggt cggttgtatg ccaaagatgg
    11641 atgcgatcat cctctgtcgt cttcttgagg tagacaatga cgactggagt gtcggtgggc
    11701 cgttccgcct tgcggaagca gggaccaagg ggctccaccg agccatgtgc agcgataatc
    11761 gtggccagcc ggcggcgttc ttccgtatgg ggattatcga tagtttcttg attcaggagg
    11821 cagacaattt cgccgttgtg aagaaagtcc caagcacgga gcagatggag ggcgccttcg
    11881 ctgaagggag gattcatcac gatggcgtcg tagtaggaga cgccgtcgta ggtcaaccaa
    11941 tcgtagccga cgacggtcag ctcctcatgg gcttggagaa tcttcaagag atcagggtgg
    12001 agttcgatca cgtcgactcg gtggcgtgac ccggaactgt agcgggaccc agtccggccg
    12061 aatcccagaa tggccttggc gagatcgcct ttgccggcgc ttggctcaag aaaatgaacg
    12121 gcattacggt tgattttctg gagcatcttc gccgcaacgg cgccgggtgt agggtaaaag
    12181 tcttcgctga acataccgct ccttttcgac agacacaggc aagtgtgaaa ggaataggct
    12241 ggcgcttttg aggaaccctc tgggcacagc actccaagcc aggagtgctg ggtgaatccg
    12301 gcacgggtga ttactgcttc ctcgccagcg cgaggatctt ccgtccctct tggatcgtct
    12361 ggaagctgag tctgtaagcg catacacgtt cgatccaggc gaacatccct ggtgcattgc
    12421 agaggagggc ggcattggcc agggcctcat cgacacgatg tcggccaagg taggccacgc
    12481 cgtcttcatt gagtacctgg caaatctttc catctcgtcg gcgaggggcc agagatgtcc
    12541 ccgcacctac gatctaagat ccatggacct ggtgtaggtt tggtcattgg gctcctgtgt
    12601 cctcaggagc ggacgccgtg cggtgcgtgc gaccaggtgc cggggcgaac ggctgaggcc
    12661 gacgaaggtg accggctacg ctagcgtacg ggtgagtggt gaaaacctgt ttttgtcagg
    12721 tcgagcagcg acacgcgttg agggcgcttc aaccagagct tgtgaagatc tttcacgctg
    12781 gcgttgtgat gcaggagtac ttccatgacg tgatagccca tgtgcgtcag cagtgagacc
    12841 agttccttct ggacgtgtgg accttttttg ggctggctgg tgtggggtgg acgttccatg
    12901 gcggcacagc ttgcgtcgtt atccagcgcg atatagatga ttcgtgaagg gagtcgctgg
    12961 agatagtcct ggaggcgctc gcccgtattc agcccattca gcgcacagag tgtaaacgaa
    13021 gggccgaaca gttcatcgcc tgcgaggcaa tccacgatgc tttccgtgat cagaatcggc
    13081 gcgttgctgc gtttcaggat ccagggacct ttgagaccac gggcgaccct cataagtgtg
    13141 ggtggggcct cgcccaaggc ccgcgccatc agtccctgca tgaaatggat gttgggtgtg
    13201 ggcaacggaa aggccacgta aggaatgcct tcgtcgccca gtcgcatcca tacagcgcca
    13261 aggtgttggt tgtaggggag tgctaacgtc tggaaatacg accggagctc ctcttcacgt
    13321 tccggggtca tgttggctcg tgcggcataa tagagcttct tggcgtgagc aattcgttct
    13381 ttgtcggtcg gcggggcgag ggagggtccg ctcggagtcg ccatactcct gacggtgttg
    13441 tgcaggatcc ggtgcagggc ttctgcgaac gtcacatgat cgaggagttg gacgaggtcg
    13501 atgaggtctc cgtggtgctt gcacccctca tgttcgttgc gtccgaagtc gtaccacacc
    13561 caggtgccgt cctgtcgctg cgacacagag aacgaaggat ttctgtcttc gcgatagggc
    13621 gcgtgaaaat cagcatggtg cggtcgtcgc gacaccggtg tgtggccgcg agagatgaga
    13681 aactcaatga ggttgatatt tcgggcgcga gcaatggcgt ctggagtaat ggacatgagc
    13741 gttatcagta ccggaaagat ggtgtgtcgt ggtgatggca gaggtgccta cggtcaggcg
    13801 gcctcgtcga agttgtagag gcgtaccggt cgtttcacaa gaagcgaatc cagctggtcc
    13861 ttgatcgtac ccatcccagt ctgaacgacg ccggcaatcg attgatcact gcgcagtagt
    13921 tgcgagttga ctccgctcag gacgtttttg gccgagctga cgagttgcgc gagttcgacg
    13981 tcgttgccaa ggttgcgggc ttcaaaggtg ttcaggaact ccagaagatt ggtgagcgtg
    14041 ctgctcttga aggttttgga cttgcccgtg tcactcggac tcaatcgatc gaccaggtgg
    14101 ttgacgagcg atcgcatggc ttctcgaagg taggtgttca cgtcctcgag catgttgttg
    14161 accttctcca tcgaccggcg ttcttctcgt ttgagcatgg tagcgctgat ggtctcaagt
    14221 gtgccgggaa gatcaaaagt aatgtaggag taggtcaggc cgaacgccgc ccgtaccgtg
    14281 tccggatcag ggtagtcact ggtccgatag gctgacttga ggcgagccgc ttcttcggcg
    14341 atccgggtat cgtattgtgc gagaaagaca tcgacaagtt gccggagttc ctcctcggcg
    14401 ttggcgataa tggtatcaac ctcggcggcg agcgccacgg ggatcaggta catgcccgag
    14461 cgaaggccgg ccggcagagt cagtttttcg agtttggtcc ggacgcgcga gtacagccgc
    14521 gtaatggcca tatattccgg acacgacaaa atggacttgg tcactcggac gcggctaggt
    14581 tctgtatcaa tggaaagcac cgtggcactg tccatccggc gttgaatgcc gagctttcga
    14641 tacgtgagca tgagacagaa agcgttcttc cagagggaac cgaaggcaga ttcagcattg
    14701 agcatgatga cctcgtttag tggtgaagat gttcgtcggt gtgatgatgg tgatgcgtgt
    14761 gtgtcaagcg ctgagtgcgt tctagttccc cgcctgagag tgtgaggatc tgttggataa
    14821 cgtcttcggc ggtggcgtgg ttggccaggc tgatctcgtc ggtgaccagc ttgatggtgc
    14881 cgtctgtctc aatcgtgatg cgtatgctgt cggtctgcat ggggaagtcg ctccaacggg
    14941 ttaggagaaa cgagtgagtc gcaattcctg cgctgcgcct tcgacgcgct ctaacgtcca
    15001 cccgaactgt tcagcggccg tttgaataat ggtttgtgca taggcttgct ttagttcggt
    15061 aatcagggtt tcgtgtcgtt gctccagcgt agcctgtcct ttggcaatgg tgattcgctg
    15121 attctgttga gtggtaaaga ccaggacccc gccattgatg gcatgttccc atccgaggga
    15181 ggtgcccgcg gcgatgagga gggggaaatc ggccacattc aattgcaccg agactcgttg
    15241 ctcgagatag cagggcatcg tgtgttcctt tgctttaagt tgagacggcc ggctcattgc
    15301 gcgagcgtaa tggtgcgagg gcgtgtgtga tgcggcgtgt cgcggttctg gtcaaagacg
    15361 ccgtcgcggt tggcgctcag ataggtttga tgcgcctgag tttcgagggc tttaatgctc
    15421 tccttggcac tgatggcagt gggaacgatg tacttggctg cctcggacag tggaatggag
    15481 agttcccagc tgagtcgcgc gcaacgctca atttccgcgc ctgtccagtt gtgatcactc
    15541 ggtcggtcgg cgtcagtggc gagaccgaat ttggcgagat agatggtcca gatcgcctcg
    15601 cgctcatcct gacttggaag atccacatac cacgtgccgt atccgaatcg acggatgagt
    15661 tcgggcggta actgactgat attgttggac gttgcaatga agcaggcctt gtcctgagag
    15721 atggcagaga tgacattcag cgcttgccgc atctgttgtt cactcgagcc gaccagagag
    15781 gacttgagac cggaaatgtc taaagcgatg gtgggaatgt tcgcctcggc tcccgtggcc
    15841 ttcgcgatgg cactcttcga ggttccgttg gggccgacga ggagtaatcc tgatgcctgg
    15901 tggtcctgca tgtagctcag cagaatcccg agtaaggctt gagagactcc tgaggtgtct
    15961 gaggcctgtc cggtcgatcc ggagaggctc ttttcaattt cgtcgagcca cacgatgcaa
    16021 cggggagccc gtttggagac caacacctgc ttgagaaagc gcttgatggt cgcgacccct
    16081 ccgatctggg cgtagctgtt tccgcctcgc cagacgctca gccctggtgt cgcatcgatg
    16141 acctgtcgtt tgcggtccca cagcttgtcg atgttcagcc cgctcgcttg catggagcga
    16201 gcaacttctt gttcggcggt aaaggcgcca aggcctaggg tggcatcgac ggctttgccc
    16261 agcgtggcgg gatcggggac gggcagcgat gcggccgaca gctgctcttt gatgatggat
    16321 tccaactgtg cggccgtagg gagcggttcg ttcaggagca ccacgtcgct ggccaattcc
    16381 ggaggcagtt tgaacccgat gcccaggagg acgatcgtgt tgccgttggc cttatagagg
    16441 tcgcggcaat tccagaggcc ctggatgaag aaatcgttgg agaggtagcg gtgcccgttc
    16501 agaatgaaag tgagcgcgcg ttcaggaacc ttttcgagga ggcggagcgc ctctgcaggg
    16561 ttgatggtcg tattctgttt cgagggcccg acatattggg catgccagtt cttgccttcc
    16621 tcgttgagag ggagcaggcc atggccaatg tcccacttga ggatgggaaa ggcgtggagg
    16681 ccgaattcgt tgtcggtctc agcttgtgag gcgcttgcga cattgaccaa tgaccaggcc
    16741 agggctcgca tggtggcggc tgggtcgagc gagttcacgg caatgagtgg gacactgacg
    16801 ttgcgggcag tacgaaaatc gagggccagc gggtattgtt cagacatggg ggatcctttg
    16861 gtttcagagc gtgagagggc gtgatccacg aaatagtgca gagcgcacgt tggtggcgcg
    16921 gtcgcttcgg gagtggcgtt agccgatggg tggggtgtcc atcagcgaac ggatgcgttt
    16981 acctgtttcg ataaacgagg catggttgtc cgtccggtag tatccgtcac acttctcgag
    17041 cagtctcatg acaattggaa agcgaggatc ttcaggatgg agcgaggccg ttaactgggc
    17101 caggcgtttg aaccgttgga gccaagtggt gtgtgggggg atgggctgcg gggctgacat
    17161 agaggctcca tgtgtttgag ggaagagacg ctcctgggtt ccttcagctg cagcccttgg
    17221 aactcccgca ggtggaacag gtacggcacg tgcctcgtcg gacgagcgtg aattgatgac
    17281 attctgggca cgggtcccct tcgtacccct ttattctggc ttcttcgagg ccgagtgtgg
    17341 tcggcggggc tgcagtctct gcgcgtgaga ggggttgggg cgtgtggcgg ctcgtggatt
    17401 tagcataggg tttgacggag tcgcctcgaa ggtcgtcatg ggtgacctgg acatgagcga
    17461 ggtcctgtcg gtcgaggtag ttgatcgcca ggtcgcgcat gatgtagtcg aggatggacg
    17521 aggacatctt gatctgggcg tgtcccgaga caggcccgtt gggctcgaag cgcattaacg
    17581 tgaaggactc gacgaattct tcgagcggga cgccgtattg caaccctaag gaaatcgcga
    17641 tggcaaagca gttcatgaga ctgcgaaatg cggccccctc cttgtgcatg tcgaggaaga
    17701 tttctcccag cgtgccgtcc tcgtattccc cggtcctgat ataaagctta tgtcctccga
    17761 tcgtagcttt ttgggtatag ccggtccggc gattgggcag acttcggtgt gtgcctctgc
    17821 cgatggcgac agtgtgggac gccagcgcct ggtcggcgtc agcgacatct tgtgtgtcac
    17881 tggagtgatg aagagggatt ttcatggtgc tcctgggagg tccgatccgt aaagggtccg
    17941 tatcgttgta ttactgattc gtgaatggtc ggggaataaa gtgggtgcgg ctacttgaac
    18001 gtgaatatgg ccgatgtgct gacctggtgg agcttctgac cccggtaata cagcatgggg
    18061 agggaccatg tcggaacaag gcattgagca gttgcgggcc cgcaatcgag ggggacatcg
    18121 agatcccatt gtggacggga aggtcttggt cggctatggc gcatgtttgc aagaccccca
    18181 gcgacgagag gggtatctcg tcatccggga tgaggatcgt tccgggcatg tggggatttt
    18241 ggggacgacg cgcattggga aaacacgact gatggagtcc attgtcgagc aggatatccg
    18301 gagccacaaa tcggtggttg cgatcgatcc caaaggggac atcgacctct tctcaaaagt
    18361 cgtgcaagtc gccgcagagg ccgggaggct ggatgaagtc atgctggtga caccgatttt
    18421 cccagactac tccaactacc tcgatccatt ggcaaattat tatatggaag atgagttggt
    18481 cagccatatc gtctcaggga tcaaggtgaa ggatgattac tatctctcta tcgcctccga
    18541 ggtttcgcag gtcatcgtct cgggattgat caaactcgcg acgagtcggg ggcaagtccc
    18601 gaccatctca ttcaatgatg ttaatcaacg ggtgggctac accgaattga tcaattttcg
    18661 agatgtctta aaggtgttga atgatacgga ggagctgtgt ggcttgatcg atcgggtgtg
    18721 ccatggtccc ggcatcgcgg aacattttgc caaggtgtcg tcgtcccttc gcaccatgtt
    18781 gagcgcgctg acctttggaa atatcggccg cattatcggg aaggcgagaa ccaatgaatt
    18841 catcactcgt ctggaacaag gcaagcgggt gatcttggtg tgtcataccg ggtcgttgtt
    18901 gagccctcgc gcgtcgctca tttttgggcg ggtctttgtg tctatgattc aaagtctcgt
    18961 tggccggctc ttcgcgtccg gtcgtcagtt agatccgccg ttgtgtgtgc atatcgatga
    19021 agggcataac gtgctgtacc cggggattca ggaaattttc aataaggccg gcggggccaa
    19081 tgtctggctg cacttctacg agcaatcggg tgcgcaaatg tcggccgaga ttggcgcgga
    19141 tctcgctcgg agtatcagtg acaatatcaa cagctggatc tatttcagag tcaatcatgc
    19201 cgagacggca caaagcgtgg aggatgcttc tccgctggtg caacgcccac ggtccgtcgt
    19261 gtccgtacaa ggcaatgtca cgttgcatct gaatgaagaa cggttggtgt tgagagaccg
    19321 tgtcttgcat ctgcccaagc ggtgcttcta catgcggacc catgggcagt ggtacaaggg
    19381 aaagacgctg gatagcagcg cgccctacgt ccaagtgaag tttcccactc ctgcggtcaa
    19441 cagtcctaaa tcggaaaccc ctccctctgc cgcgtaagcg tagggcccga gtctggattg
    19501 ccgatggcat cttggacccg ggcgatcatc gagcgggtca ccatcccgac acacgtgttt
    19561 cccgcaaaca ccaacagctg atccgacccg ctcaggagca tcgcatcgag cgcacgttgc
    19621 agggtatgag tggggtgtac gatcacatct ggggacaagg ctcgaatgaa cggggtgatg
    19681 gtcgctccgt tcggcgcgag ccacttgggg tctgtgcgta catccttgta atacaccaat
    19741 ccggtgatcc gtccgtgctc ggcagtgggg taggcacggt acccgtagcg aagaaactgg
    19801 tcttgcagtt ctaggagggg cgtatcgtgg accagcgtca ccacccggtc ccatggaatc
    19861 atcacctctt gcaggggtcg ggtgagctgt tcgctctgtt gcacggtgcg atacgcggtt
    19921 tcggcgatca tgcggaggat gccgccaata atcgcaagcc acagcgtttg atactggaag
    19981 atgatgccga ggatgccgat ggccatcatg ccactgctga tttgtttact catttgagcg
    20041 gtgcgctcag tggcaaccgc aaaggaatgt gtttgggtcc ataagacggc ccgtaagatt
    20101 cggccgccgt ccatcggcag gcacggaatg aagagattgt aggcgccgag cgtgaggttc
    20161 actttgtaga gaaagttcgc cagcgggtct gctttcatcg catagagcag cagggtaagg
    20221 agaaaggaac aacctggacc tgcgatggcc acgagaattt ccacccttgg gctggacagt
    20281 tcacgctcaa aaatggtcca gcctccgaga atgtgcaatt cgatggtttt gacggcgtag
    20341 ccgagtcgcc gcgcggtgac cgcatgggcc aattcgtgca ggaacaccga gacgagaatg
    20401 aggagggtgg cgatcgcacc ggaagcccac tggtagctga cagggaggtc agcctgcgtg
    20461 tcgtgaaagt agttggcggc gagactccag gtgatgagac cgaatccgat gagccatgtg
    20521 taatgaagcc gcacatggaa attggcgatg cgaaacgtca tttctactca tccttattca
    20581 gcgggggtgt gtgtctggag atgcgtgtga cggagcgcgt ggtgctgctt cgagatgtgg
    20641 gggcagcggg ctctctcgtg ggtttagctg gtcgcttgtc gggcggggcc aactgcgcca
    20701 caggtcgcgg gggatgtggt tccattcgtg tctgatcgat gggcgccggt cggcccttcc
    20761 acgagctctc agccgattcg aaccgccaat gtcccttcgc gaggtcctgg ggcgacgcct
    20821 gcccggccac atattggacg actttgaggg cgtcatcgac ctcatcggca atggcgacga
    20881 ggatcaaata tcctctgggg acgacgagat agaagccgcg atattcccgg tctttggttt
    20941 cgccgcgttt cacttccacg atgtccccga ttgcggcgtc gaaggtacat tcgccaaccg
    21001 ctccgaaccg acccacgggc gtaatttgga tggcataaaa gccgcgtgcc agcgatttgg
    21061 cctcggtgtc ccaggtgacc cgagccacaa agggtcgatc cttccgttcg cattgggtgc
    21121 ggaactcaaa gcggaatgtg ctgggaggct tcatcaggct tgatccatct cgtagctagg
    21181 aaggatgtca tctggaatcg gcgcaagaaa ccggcagagc gagtcgagat tctgcttgga
    21241 cgcgttgtgg tagtgctcgg ttgggtaggt gagaaagagc tgctctctcg gccgtgtaat
    21301 ggcgacatag aggaggcggc gttcttcttc gagggcctgc tcttcatgcc aacttctgac
    21361 tggaggaaac tgtccatcga ggacccagat gacgaagact acgtcccatt ccaagccttt
    21421 ggcgctgtgg attgtggaga gtacgaggtg gtgatcgggg tgtgcatgtt tgctgctcga
    21481 ggtggccgag gggttcaggg tgaggtcttc caagaacgcc gccagactgg tcgattgtcg
    21541 tgcgaggtcg cagagtggtt tcaggtcttc gatccggact ttggcatctt ccggataatc
    21601 gcgtttgagg atcggttcgt aatgcttgat tacgaaggtg agacgatcgg ttagagaaat
    21661 gctctcgtcc tgtgtcgtcc gaatgacgtt gtttaagagt ctgatggtcg attcggcttt
    21721 accaggaact tgatcgagca cgtccagagg gtgaggagct tcctgcattg tggcgataat
    21781 ccgctcggcc agcttcggcc cgacgcgatc gagcagcagg aggaggcgat gccaggcatt
    21841 gctgtcgagg ggattgtcgg ccgcccggag gtaggcaagt acgtctttga agtgcgccgt
    21901 ttcggtgagc tggaggccgc catacttgac gaacgcgagc ttatgtcggg cgagtgtcag
    21961 ttccaggttg ttggagtgag cggaggagcg aaagaggacc gccatgcgat ggaggggaat
    22021 gccttcatca tggcattgga gaatgcgctc cgtgagcaag tcgctctggg cctgttcgga
    22081 ataacaggcg atcaattctg gagactgtcc tccggccttc gcggtgaaga gccgttttgg
    22141 atagagatcc ttcgcatcct ggagcactgt gttggccagg gtgaggatcg gggcggtgct
    22201 gcgatagttg tgctcgagtt tgtagagccg cacgctaggg aaggcatcct gaaactcgag
    22261 catatttttc gtatgggcgc cgcgaaaacc gtagatgctc tgggcgtcgt ccccgacgac
    22321 catcacgttg tggtggtggc tcccgaggag ccgcacaatt tcggattgga gtttggtcgt
    22381 gtcctggtac tcgtcgacca ggacggcctg gtagtgcgtc ccgagtcggc ggcggctggg
    22441 ctcatggagg cagagtaact tgtagaccag gtacagcagg tcgtcatagt ccacgcgatg
    22501 ttggcgccac ttcgtttcgg tataggctcg aaagagcacg acgagctgag gggtgtgtgc
    22561 gtccagccac ggaaaatcac gggagacggt atccgcaatc gagcggagcg tattcacggc
    22621 ccggctgaac agggcgagga tgtgttgttt tttgggaaac cctttccgac gggaaaagga
    22681 cagtttgctc atcaataagt gcacgagacc ttgcgcatcg tcctcatcca taatgctgaa
    22741 cttgggaggg agtccgagcg cgccgccata gtgtttcagc cagatcaacc ccatcgcgtg
    22801 gaaggtgccg ccttggatct tcaatgagtg ctgctggagt agcagttgtg ttctgtggat
    22861 catttcctct gcggccttcc gagtaaatgt aatgaggagg atttgatcgg ggggtagacc
    22921 ttgggtgacg aggtgtgcaa cgcgatgaat aagggtgtgg gttttaccgc tgccggcgcc
    22981 ggccaaaacc agtgtcggtt cggccggggc ggtgaccaca gcgagttgct caggattgag
    23041 ttgcgcattc tgaatgaggg gcgagatcgt ggccaggttg agctctacgg ctgagtgtcg
    23101 ctcttgggta agatcgttcg gggtgtggat gtgtgcatgc agccagtccg ggagtttccg
    23161 aggcgacagc gggagaggcg atggctcaga cggctcctct gccggtagag gaggatcgag
    23221 cgggagagga aacacggatg ttgtgttggt gtcgtaggcg gacatgaagt acctatgtgt
    23281 tactggatct gaacggactg aggctttggt ggaataaggc gacgagggtc gccggtggca
    23341 ctagcccgca ttattcatga gcggttctac tgcaaccgct gatccgctgc tgcgacgcgc
    23401 cttcggccgg cgggctcgcc cctcggaccc tccacgtact gcacgagtac gcgtcggggc
    23461 ctccggactc cgcgcgccgg tctcgcgacg cgcctcagcg atttcgtgac gacccgtcat
    23521 gaataatgcg ggctaggggg tgtggatgcc aggagcggca gacttggtcg tctggatgga
    23581 aagcggcgtg cgcaagaacc gacagtatcc ggcggtttga ggatcaaggg cgtgggcggc
    23641 ggacgagaag tattcgcagg caatgcatgt acgtatgatc gggagtgagt cggtagcgat
    23701 catgttccgg atggcctgct ggagttggtg aaccaggtct cgtaccccgg cgacggagcc
    23761 gcagcgcgca tactggtaga agctcgtggt ccaggagtca agcgagactg tcacggtgtg
    23821 cccaagcggg gtaagcccat agactgcttg ctcggacgtc cgttgggaca acatgtggat
    23881 ttcctcgcgc tggacgaggt tgatgagtgc gctatcaatc gtgaacggat tgatcatggt
    23941 gatttggcgc aattcgaggc gcgtgagcgg gcgatcctca ttggccaggg acacacacag
    24001 gatcaggcgt tcggccagtt cgatcggggt atccaatcgg tgttctgccg caaagttgta
    24061 cagggcgatc ttggagaggg tggtgcggag tgcagaccga tggtcgtcag ccgagtgggc
    24121 ctgatcgacg gaattgaacg attcgggaga ggaacactgc atgtgcagat tctccgattg
    24181 tcgcagctca ccagtacaag tatttgtgag tatgaacaag tgtccaaatg cctgttggcg
    24241 agggaaggga gttggggatc tccctagggc gcacgtatcg ctagctatcg gcggagcgat
    24301 ctccgttcac tgaccgcgag ggtcggggga tgctctggag cgggtccgtc ggcctcggca
    24361 gcacctgctc gatcgcgccc agggcttggt tggtgaggtt gatatggtcg agaatcgtgg
    24421 tctggtcagg ggtggtcagg gtggtcattt gctgggcgta agtctggagt actagaacgg
    24481 tcttgcgggt atgcaagagt ccggcaatca gggggccggc ctcttcaatc gcggggcctt
    24541 ggcggcgacc tttgtgctgc aagcggagaa tgcgctcggc tttatggtcg agattttcgc
    24601 ttgtgagttg tcgctggagc gatgcgaggt tttcgttcaa ttggtccttt tcatctgact
    24661 gctcccgcag ctgacgagac agggagatgt tgtgctctcg gacagcctcc aactccttct
    24721 tctgcagagc gatccgtcgt tcaaagtcct tggtcatctg attcatctga cggattagct
    24781 gtttgtgctg cttcggtatg ggggcgtccg gagcctccgg ctctaccggg gcggggctgg
    24841 tgtgctgtgg ctccgactgg ggctgaatgc ccactcgctg cacttgggcc acccacttgg
    24901 agaggaaatc gcgctgagtg tcgtggctgg attgtgtcag ctggagttga acttccggcg
    24961 gcagcatggg gagtacatcc agaatctctg gaatcaaccg ttccctcagc ctggctcggt
    25021 aacgctgttc ctcatcctgc atctgtcgac gaagggtgtc cggcaattgg cgtcgatgga
    25081 tattgtcgaa cagcgcagcg accttcagtt ccatggtggt gacgatgatg caggggacct
    25141 cggggatgtt cagttcctgc gcgatgctca ggcgatgatg gcctccgagt actacatagg
    25201 gctggacgga ggctgcgtcg gtaggctgtc gttcgactcg caggggatca tggatcccgg
    25261 cttcttggat actggttttc aggctcgctc tctctgacga cgtgagcggc ggaaagagcg
    25321 tggcgtactc gtcatggact cggatttgag atgtaggaat catgatgatc tgcatgccgg
    25381 gctccttgtt gctggctgtg acgagcgatg attctgtaaa tgtgacgtcg ggacaggtcg
    25441 tggccgcgac gatgaagctc ccgttggagt tgatgactgg tgattgtggg ttgtcggcga
    25501 aggatgccat tagcaatctg ttgagcacag gattctggct cggcgaggtt cttggttagc
    25561 tgtcgtcgga tcgcaaagac gcgatggatc tcggacaaat agcggagagg aacgacatat
    25621 tgccgacctc gatagcggcc ttgagagggg gtggtaacga tgtaccactg ggccggtgca
    25681 tgctggagga tggcttgtac cggactgggt agactctccc gttccaacgt taaccaacga
    25741 tagagtttcc aatcactgca gggaatgttg tggccccggc agatgtcccg gaacgcgctc
    25801 atggggagca cgggctccgc gggcatcgga gtcggacccg cgcgaagtcc cacctgccgg
    25861 cagatggttt cggctatgat ccgtgtcata tcagttggca taggtccgtc gtttccgtgc
    25921 ctggcgagcg tggttgccgc tgccggagga agatcccgtg atcgactgtt ccgacgtggt
    25981 tagcaggtcg tgatcgagag cagtcgggtc ggggatcgct ctggcgcgtt tgcgcgagaa
    26041 ttcgatgaac cgatcggtag ccgtgaaacc caagacgtcg tcggtgccgg gcacatcggt
    26101 ctgtgccaaa gattcagccg aggcgtcagg gacgacaggc ggttcgtggg tcgtcaaagg
    26161 gacaagccgc cggaagatac gacttttgaa gccttggctg tgtaagcgcc gcttctcttt
    26221 gatgaaagtg gaatagggca gtgtcttgac gtattgatcg tccttgtcgg tgatttcgac
    26281 cagtttgtcc cgtccatcga attcgctttg gtaggctttc tgaatatagc gatagaggaa
    26341 ggtttggaat tgggcgtttc cacgggaaaa gtcccatttc tcagtggcct tcctgacggc
    26401 cagaaagccg atctgctcca agtcttcaat ttcataggag cggtctaaat tgcagtagcg
    26461 tttcgcgatc gagtggatga tgggcttgct ctgctgaaac agtttgagca gcggtgagtc
    26521 attgtccgaa tcgatggcga gttgttgagc ttgcgttcga aacgacatga tggtgtcctt
    26581 tccgatgggg tagatgtgtg agaccatgcg tctcggaaaa tgaaagggtg cgtgacaacg
    26641 ctgatggagc cgatgatggt tccgtgcgta agtggtgtga cattcgtgcg gcagtccctt
    26701 cttccaggga gcggcgaggg atgatgaata taaacaaatg tttgtttgcc catgaatgtg
    26761 ttactgcctc gtgaatgtca gtctgactat acgcaggccg tgagggaggt tgaaattggg
    26821 aaggtagagt aacctccata ggcgtatgga caataaattg gggtttacct ataatttgcg
    26881 aacaagcgtt taatcactcc atcagcgtgg gttgggtacc cgtcggggcc cgacggggag
    26941 agtgtggtgg ggatggtgtt ggtcaaggac ttgttggtcc ggatgcggat tgcccagaat
    27001 ctgactcaaa ctgagttggc tgagaaactg gggtgtacgg cctcgcatat ctcgattatt
    27061 gaagggggaa agagcagtgg gcggaaaaag attcttccca gtgacgacat gttgcggcgc
    27121 attgcgcagt gtctgggtgg atccccgctt gatgtccaac ggcggaccta ccaactgttg
    27181 gtcgcccgag cccgtgaagt gtgttccccg gaagtcgcag aactcttaga tgatcagatt
    27241 cttactggca tgccggctgc ctttttggag cgggttaagc aagacctgag tgagtattcg
    27301 gatgaggagc tagctggggt gacggaccag gtacagctag gtggaagatt caagcaggtg
    27361 ctatcgggga tcggtcgctt gagccaagcg gaagtggagc ggctcgccca ggtcttagga
    27421 cagtcgtctg agacatatct agtcgaggcc gggtatctat ctgaatccgc gagatcgctg
    27481 ttcggacgca atccgaattg tgtgaatatc cttcaagtct ttggatccct gcgcccagaa
    27541 acccaggaag agttgctgcg ctttggggag gcctccgtga gccttccggt ttctgagcgc
    27601 atgcacccac ctacggctca tgagtagcgg attcttgacg tgtgcccgcc cgtggcagta
    27661 gtgctcaggg acggctcaca gccgtccctg agtcatcccg atattctccg tgtctgtctg
    27721 ccagcgaatt agaactctac tttctcttct actggtgcgg attctggagt gacaagcact
    27781 ggcagctcct cctccttcat ctcctggaat gctgaaaaat ctccaccaac gagctggtcg
    27841 atgagggtcg aggcctgtcg tttagtatat ccgctggtga gacttttcac gtgtgtctcc
    27901 tggatatcca ttgagatgac gaggcccatg atcttcttga actgaggatc ggtcatggac
    27961 tcggcgacgg cccctgtgtt cgcaggcgtg atcgggggag tgcctgggct cgacgtgaaa
    28021 tagctaaagt cctgagcgat gagtctcttg atgagccccg acgcttcgcg ttgcgtgagt
    28081 gcgcggacct tcatgcgaag atcatcctct gtgaggggca aggccttggt caaccgaagc
    28141 aggtagttgg tctgggccac tgagatgagt gggccagcgg gcaggggggt gggctccggc
    28201 gctttagcgg cggctgtcga gggcgtgaac atcgccggag gtgtggggtc gtgcgtctcg
    28261 gacggagtgt cccccggaac ctcggctgct acaggaccgg ggtcgtcctc tagctcctct
    28321 tccattacaa cgtgcgctcc tggatccagg accgggttga tttcgatcgg ctcttggatt
    28381 tccaacatct tgatcttctt taggaccgtc tccgtctcct gttgatacct ggcagtctcg
    28441 tccgctgatc cttcatagcg caattcgagc ggatagtggg tggtcgggcg gccttcgcgg
    28501 cgtctggtga ctggaacgcg acgcagtttg agcgggatca tggcgatacg tccaagggta
    28561 agcgcgagga aatcgaaata ggagttaatc gtttccatcg agttgatact gctggagtcg
    28621 atttgaaaca gaccgccgct gctgaccttg gggatcatga agatgagatt cgcgcgaggg
    28681 ccgcattctc cggattcgag tttttcgcag ggacacgacc gggattcggt tttccaggtg
    28741 tcttggttca ggcgacgagc cacctgattg ttgccaatgc actgcagccc ggcggcttct
    28801 ccgtaccagc gtagggcctg cgggcaattg accgtgggat cgttggagac gaacatcacc
    28861 tccagctcgt tgggttgcgc cccgaacacc ttggcgacct cttcagggac cacaaaatga
    28921 ggcgtttcct tggggtagaa tccgttgggg ccgctcactt tcacgccgag gcggatcttg
    28981 ccgatgatgg gcatgcgacg tcggttagaa atgccgttga tgcggttcat gggaatgaac
    29041 gtgggttttt ctgcgtcgga catgatgcct cctactaatg tgaatcagcg catgaataca
    29101 gttacgcgat ttgagtcgtc ggtttcggct tcttgagcgg ggaccgacgt ttcgatttgg
    29161 tggtgtcgat gcctttggac agtcggccgg ctgagaagcg gctgtaggat tctttcacgg
    29221 tcgcgcgttc aatgacggct ttggacagtt tggattgatc taatttgctc tgttcatacg
    29281 gtgacgatgc gatgtagtag ccatgccctt ccgcgcgtgt gataccctct gtcttcaatt
    29341 ccaacttaaa ttgctgtttg agtgcgtcca accgcttttg cttcggagtg agtgctgcga
    29401 gctcggtttg caagccgaga tactcctcga cggctggcac cagttcagtg cggagttccg
    29461 cgattccctc aacggggacc tgttcgatcc cttcccagca aaactggtac ggacagtagt
    29521 cgcaatggta gttgtcggca ttgggatatg ggcgggcagg caatgtgccg tgatcccgat
    29581 actgttccac ctcttcaaat cgacgtagtg cctcctgata taagcccaca aagtcttgct
    29641 tgggatagat gcgcgcgcct gtgctgtgtg tgatttcgag cacggtcaag cggtcgttgt
    29701 cgcggtcgta gcggactcga tattcgagga acgcgctctg gtttttgttc ttgatgagga
    29761 ggagcgcttc gtcgatgtga ggattcagtg cggccaaccc aaccagatag aagaccacct
    29821 gtacgaagtg gtttatcggg taattccctt ctgcaaagcg agtgaaggtg aagtgttcga
    29881 tagccttcaa ctccaggagg cgatcaatcc ccaagaggtc cgtgatgacg ccgtcaatgt
    29941 gacctttgat tgggaacggt cgaccctgga agagcgtggt cgcgcaggtt aattcaagct
    30001 gttggctgtg gagatgaaac gtgctcttgg agatccagtt caataccagt tcttcatgcc
    30061 aactactgtc gtcgaggacg acaaggaagc ggccgcttgg acttttcgcg ggagcgtgtc
    30121 gagcatggta cgtgagtttg cggatgcagt ggtcggggcc ggcgttcgat ggccgaggtc
    30181 tatactccca ttcctgatgt tccatgagag cgagtggatg gatgagttca gcgagcatag
    30241 gacctccagg tgagttcgtg tagcgcgtcg atagaccaag aggttgtgcg gttcgctgat
    30301 gtgaagatgc tgtgacatac cgttttggga gcaaaacggt atgtcacaga gttgtggata
    30361 cgagtgtgtg atggctgaga atgggggagg gagaaggatg aacggctacg gatcgatcca
    30421 agggagtatg caggggaagg acgtctccgc caaggtggcg agctgccctg aggaaatgcc
    30481 tcaggtggtt ggggtgatca cgagtcggac ccgtgcgcga cgaggggctg gtgactggat
    30541 cgaaatcggt cgcaagcatc gggcgtttgt tccggacggt attcccgtgc cttcggtcgg
    30601 tgaggtggga gagtgctggg ggcgaatgac agccaatggc gccgatcccg ttctgatggt
    30661 ctccaggata cgatcacgac gatttgaagc ctgcgcgagc ccgtcggagt tgctgggggt
    30721 cctcggcgtg cgtcgtaccc caccacttcg gttcgaggag gtatgccaat tgttaggccc
    30781 cctggtggaa tggctgtgtt gtgcagggtg gaaagcagtg gcgcgtggga tagtgaaggg
    30841 cacactgcga tcggcgcggg ccatctccgc agatccgttt ctgctgtacc gccgccggcg
    30901 ccttcccttt caggctacgg tcgcggccgc gcaggtgtta gggcatgagt tgtgtagtga
    30961 cggacactat aaggccgcgg tgatggaggt gctcgcgcga gccgacgaag aaggggtcgg
    31021 aggcatttct gaggcgcatc ttgtggcccg ttgcgcagag ctgatcggac tgcctgcaga
    31081 caaggtggcg ccgtcggtga gcatccagat ggggcttgtg gggaaattcg agcagggctt
    31141 gtggttttcg ccggtggtgt atttcgcgcg aaagaaagcc ctggccatga ttcgggcgaa
    31201 tcagcaggac tctggtgacg cacgttcaag cgtgcaagcc agatcgctgc ggtatcggta
    31261 ttcgattgtc actggcggtg ctgggagtgg aaaaaccgag ttagcgaaat ccctcatgac
    31321 ccaggtgcgc gagcaagggg gaaaggtggc ggctacggcg atgaccggga aagcggccac
    31381 cctcctcggg gaggacgcca cgacgctgca taagctgctg gggtatgggg gcggcggcta
    31441 ctcggtgtcc actgtggatg ccgacctggt cttggtcgat gaagccggca tgttgacctg
    31501 gcacaccttg tatcgattgc tgctcgcctg tcgggggcag gttgtgttga tcggcgatcc
    31561 ccagcaactg gctccggtgg gagcgactcc ggtgatggct gagttgttga cagtcctgcc
    31621 ggtggtgcgg ttgggcgaag aaggctccaa ggggtccttg ctggtcaagg ttcaggtaat
    31681 tcgcttcgcc tccgaagcgc tcctgctgta tcagttacga aaaatagtgc gcggctatca
    31741 agacacaggg gtggagtggc aggcgttgtc tcctgtgtat gcaggaggac tcggtgtgga
    31801 tcggctgaac cggtggctgc aggagattat gaatccggat ggtccgccgt gtcatggcgg
    31861 gtttcgaacg ggggaccgcg tcatcgtgac caagactcga tacgatatag gccagcgagc
    31921 ggtcaatggg gaacaagggc gggtgctggg gagtatgggt gacacgatcg cattgcgact
    31981 ggactccggg cgtgaggttg cgctcagggc agaggagctg cggctgagct attgcattac
    32041 cgtgcacaag gcgcagggga gtcgctatga gcgcgtggtg tttatcattc cagaacggga
    32101 gtgtggggcg tttgcggtcg aggagcgcat gcaatatgtc ggcagaacgc gtggacgcga
    32161 ggcgacagtc tgtatggtgt attagcgtgg gggggggtgg tggatgagcc ggaggcgctg
    32221 gccagtgata cggcgatgca gacccatgag cctgcgtgcg gtcggagctg gcacggtagc
    32281 gcccaaggca tctccgagcc tggaccgtgc cctgaggttg gaatatcacg gcacgagtcc
    32341 ttgacatcct ccccggcctg aaggccgggg aggatgtcaa gtatgcgttc tagcgggcaa
    32401 gaaccgctgg tgcaacgggc tgaacagtgt gccaggtcga tcacgtatgt ggcgggagaa
    32461 ttgatacgcg aacgctttct gcttggcggc atcgtggctg aagcgctgga gcggagccag
    32521 tatggggatg cggttatcgt gaagatcgcg taccgcatgt ccactgcggt cgggaagtgt
    32581 attcgtccgc acatgttgta tgagtccgcg aggatctaca gtgccttcgg gggacagtgg
    32641 gagcggattg aggccctgcg caccgggtca gattgcgtca accggggggt tcccggagct
    32701 cacgtaacga ctgttcttca gcaatcagtt gcgcagcccg tgcttgaatc ttttcttggc
    32761 gtctcgtccc cagttttttg atcttctcat gcagtgtggt tgccatggtg gtctcccttt
    32821 ctgcctcgct tttttattgt cgcgaggcgg gcgtcgaacc gatgatcggc tgtccgtatg
    32881 agcgcacgat aaaaacgctt ttcgctgcca ggcttaggcc aaacgacgcg tccgggtcac
    32941 tcgcctgtgc ttgggaggct gtagttcgac gcgaaccggt cgccccagtg ccgccgccat
    33001 gttcaccagc gcatctaagg aaaagcggga gatccgtccg cggagcagat cattcatccg
    33061 cggctgcgtc accccgcatg tggcgcccgc ttccgcctgc gtccacccgt tcgtctcgat
    33121 gaccttggtg atctgccgca tgagtgccgc gcgcgcacgc aagttcgccg cctgttcggg
    33181 cgtatcagcc aacgcgtccc acacactctt gaaactgtgg atcgtcttag tcatgtttcc
    33241 ctcgcttgag ttcagcgtac cgtgtcctgg cttgctcaag gtcgcgtgca ctcgtcgccc
    33301 ggcttttctt ctgaaacgca tggagcacgt acaccgcgtc tgcgaaccga gcaacgtaga
    33361 gcacgcgata ggtgccggag tcatcccata cccgtagttc ttcgacaccc tttccaacgg
    33421 acggcattgg tttgaaatcg gttggctgct tgccgtgctg gacttgctct agttggtacc
    33481 ccacatcatg ccgagcgtct tccggaaact gtcggagacg ctccagcgag ttcccaagaa
    33541 agcgcagcgg tttcacggat caagtatacc ggtgtggata tacgacggca agcccacgca
    33601 gaccctgacc ctggggattg ccgtcgcagt ggcgagtatg tgtcagatcc cttccctcga
    33661 acgtattatc caaatgttaa gaggttagct gtcttcatca gtgtcttcag tgcgctcggt
    33721 tattccaacg atcgaccgac gggtccttcc gagtctgggc tggacgcgtg gctcctggcg
    33781 atctgatcgc ctcctgatct gcttgcgtcc cctcgtgcct acttcgtcgc gtcgacgagg
    33841 tccccttcga catcctgcat cttctgttcg tccgcgagac accgtggcag tcggtaatac
    33901 caaggatgag cctggccatt cgggagccat ggtgaaaggg ggaagtatga cagggggacg
    33961 gccgacttac atgtcgtggg ccggtctggc ctgtgtggga ctgctgaccg tcgggggctg
    34021 taccacgaga cctgccgtgc cgccaacaat gtcagatcca acgcgacttt gcggacaggg
    34081 ctacaccttt ccgacaacgg tggtctcggt ccaatctggt ccgcaatggc tgctgtctcg
    34141 tccgatggga tgtccagaac cgacgccgct cacgcaggta cctaacaagc cgacggtggc
    34201 ggatctcccg ccgaaaccga tcaaagcagg gatccatcgg ctacaggggt tgccgacgtt
    34261 ttcgtcgggc acactggcag ctcgtccggg tgacatgtcc cgcgctccgg gaagcagtcc
    34321 ggacaaggct gtgattcctg gtcccaccgg aagcccgacc acggtcgtgt gccgtcgcga
    34381 gcctgaggta cggcaccgaa gggtctcgtt cgcaatgggg tcggccgacc tgtcagagcg
    34441 tgcgcaacgg gacttaacgg aactacgcat cgaggagatc ctctatctgc gggtggaggg
    34501 atacactgat ccgacgggat ctcgggagac aaaccaggaa ctcgggatgg cgcgggcaga
    34561 ggcggtggcg aaggtgctgc aggcgcgcgt caaggggccg gttcaggtgg aagtggtcgg
    34621 tcgaggaggc tgctgtttcc tgccgaacca cgcggagagt cgacgcgtgg aggtcatgat
    34681 gctgttgcaa ggcaggtgtg cagattcctc cgaggttgag cggcgatcgg aagcacctcc
    34741 ggtaacacct gtggtgtcag ctggtgccac tcacgactca gggaaaccat aatgagaggc
    34801 tggagaggag catgacaatg ctggaatgaa ctgagggcgg tcattcggtt gggcaaccgc
    34861 agtcttctga actgtgaacg acgagccaga ggaggggctt gagtatgggc gatggcttaa
    34921 ggaaagtggc cggagacatt tggcgaatga gtcttctgtt ggggctcatg gtgttggcat
    34981 cgtttgtggt gctggccgtg cccgcgttcg cgggtgcgga tgcgacgttt ggccccttgg
    35041 tcacgttgtt gaccaactat atgcaggggt cgcttgggac gttgttggcc ctggtcgcgg
    35101 gagcgatcgg cttgggatcg gcgatggcgg gccgttgggc cggcatgttc accgggttcg
    35161 gtgtggctgc cgccgccttt tatatcccca acatcatccc gaccattacc acgggactga
    35221 tgtaagcgcg cgttgcaggt aaggcgtcgt gacggcgggg ctgatcagcg ccccgccgtc
    35281 acaagggagt aggagaggga ctgatgaacg gcacatttat tccacgatat ctcgatagcc
    35341 tgccccagat cttctggtgg gagattgatg agttggccgt gctttttgtg tgcatctttc
    35401 tcggcattgt cacgaagttc ctgacctacc tgattgtggt cgggatcgtg agcacgttgg
    35461 tgttgtcgaa aatgaagaac gggaagtccg agggattcct cttccattgg gcctattggt
    35521 ctggtgtgcc cacgtttcaa ctgacagggg caccgcacgg aaccacccga gagatgatgg
    35581 agtaacgacg atgacaatcg agttgtggaa atccaaattg cataacgccc aggttttaaa
    35641 tcttgtgttc gcggccctgg ccatcgttct cgctgtggcg ttggtggtga atggattctt
    35701 tcggcagaac gtcgcggtgc acgtggtgcc gatcaacccg acccaggaat attgggcgaa
    35761 tgcgatgggt ggcgacgagt attacaaaaa gtccattgcc atggccatgt tgccgtggat
    35821 tgccaatgtc acgcccgcct ctgttgattt tcaccatcgt cagctcctgc agtgggttcc
    35881 atcgagccac tatgggctga tgtccgagtc tcttggagcg gaagccgtgt acgtgaagac
    35941 caacaatctc agtcgggtgt ttttcgtgac agccagccgc gtggacgggg atatggccgt
    36001 gttcgagggg atcgagcgcc gatttgtggg gaagagtgag attcgggaag aggagcggga
    36061 gtaccgcatt tcgatgcgat gggagcaagg gaggccgtgg gtggtcgggc tctcagcggt
    36121 tcatttggat cgttcgctgc aggatggtca atcagatccg gcaaaggggt aaggggagac
    36181 gtatgacatc cagcgtgtat cgagacacaa agcaccgggc gatggcgatg tgcgtccttg
    36241 gcctgctgtt atgcttatcc agggccgggt cagcaggagc ggcggtggtg gtgggtgatg
    36301 aaggttcgac gcccctcacg ttgtccggaa gggatttgaa cgtgctgacg tttcccgcgc
    36361 cgatcaccat ggcgacgagc tctagggcgg atctcaaggc caaaccggaa gggcgcaacc
    36421 tgatcgtcca ggtcaagacc ggcccggccg atctggtcgt gatggccggt gagcaaacgt
    36481 acgtcttcga agttgtggtg agcgcgtcgc tcggtgcgca gacagtcaat attgaggata
    36541 ggcgcgcggg gactgtgccc tatgattcgg atcctgcccg ccaagccggg gactatgtgg
    36601 atgggctact cgacacactg cagatggctg cgcgtggcgc gttgcccaag gggtatcggc
    36661 agacgacgat gaacgaagaa cgatatccga agtggcttga gctgaaagtg gtgcagggag
    36721 tcgagtatcg agggccgaag taccgggtga ttgtgtatcg attggtgaat acctcgggac
    36781 aaaaatacac gttgcgggaa caggaattcc tgactgggac tcaaaaagcg atcgccttaa
    36841 atcgcgaggt ggtcgagtca ggcgaagaag tggtggtgta tctgctggat gacgctccgt
    36901 ctgaaccacc caaacccaag ccggagcaga aagtggatcc agacgcaaag ggctaacctc
    36961 agaccggaga cctaggatgg catcgattaa accgacggag agcgcgattc tcaaccctgg
    37021 cgacccgatt cggccagaga aaccggcccc ttcaaagctg ttggcgggag ttgtcctggt
    37081 gggtggattc atcgtcctga gcatggtgct gcagcaattc cgaggcaatc aaccagggat
    37141 tgtccgtggc aagtctcccg tcaaggccgt gtcgatcaat cgtgaggcga cggacaaaga
    37201 aatctatatg aaggacgcag gggccaggat tgaggcgttg gagcagcagc gggaccaaat
    37261 gcgtagactg ttggagcagg atgggcgaga caagacagaa atgaagacac agttgagcga
    37321 tctgcaaaag cggattgagt cggtggcgcg ttctggtggt ggggccttag ccgggacgaa
    37381 gagtggcgcc ttgcccccgc tgcctcctcc gctcagtgcc aatcccttgg gtggagcgag
    37441 cgcgacgccc gtctcgacca tgccagcgcc gaaggggccc attcccgtgc aaagcgcccc
    37501 gaaaccgaca ggcggggcgc ttcctgctcc tggggttgcg ggcggggcga ccgaggcgtt
    37561 tcaggtgttt cggccagaga cagtgcctgg cgccaaaaag cacgaaaaga aactatggct
    37621 gaacacgggg acgattatcc cggtcaagtt actctccggc atggatgcgc cggctcgttc
    37681 gacgggggcg cagggcgggg gggccgctgt aaacagcccc tacccggtgc tcatgatggt
    37741 gcgcgacatc atgaagcttc caaatgaggc gaggattgat gcgaaggatt gtttcctggt
    37801 gggagaaggc ttgggagatt tgtcatcgga acgcgtaatg attcgcggca acgccatctc
    37861 gtgcgtgaaa aagaacgggg aggcggtcga tatcgaattg aaagggtttg tcagtgggga
    37921 agatggcaaa caggggatgc gtgggcgagt ggtcttgaag gaaggggcat tgttgggccg
    37981 cacgctgctt gctgggtttg tgtccggcat ctcgcgggcc ttcatgccct atcagtccgg
    38041 atttttcgtt gcccaaagcc cgagccaagc cttcaactta ccgccggccg ggccggtggc
    38101 aatgtcgggg atggctggtg gcgccggtcg cgccgcggag ttgttggctc gtcattacag
    38161 catgatggcg gcttccattt tcccggtgat cgaaatcgac gcgcagcggg aagtggattt
    38221 tatcgtggga acgggacgcg agttggaggg gttcttccag taattcaaaa gagggcatgt
    38281 tgcgatgaaa caatcttatc agcagctaat ggcgggcatg ttgtgtgcga tatgtgtgtc
    38341 ggtggtgtgt gagcctgatt tgagagccga accggatgat acagtaatgc ccatcaaaac
    38401 ggtgatcgaa cagaagtttc ccggcatgaa agtgctgcga gtgtccaaga tggaaatccc
    38461 agggtggctt ttggtagaga gcgacagtga ccgagtggaa aacttcatgt acgtgcatga
    38521 ctccgggaga tacgtgctct ccggggcact cttcgatatc gagatgggcc ggaatgtgac
    38581 gcaagagcat gtgagggatc gtcaacaggc gctgctggcc gggatggatg cgtcgaagac
    38641 catcctactg tctccgatgc aaccgaagtt ggatcgcccg ctgctggtct tcgacgatcc
    38701 agactgtagg ttctgccagc agtttcatcc ggaggtgcaa aagctcgtcg aggcaggagt
    38761 tccggtagcc gtggtgctgt atccgctcgt gcggacgcat ccggatgcgt atcgcaagtc
    38821 cgtcgccatt tggtgtgctt ccgaccaagc tgaggcgctg gggcgggccc tgatgtcaaa
    38881 gccggtggtg ggggaagcgg ggtcttgcag tcatccgatc gacgacaaca tcaaattggg
    38941 gaagcggctg ggggtgcatt ccactccgat ggtgttcttg ccgaacggtc aatcgtttgc
    39001 cggttatcgt cctgccagtg aagtgttggc gctattgcag ctagagatgg agcagaagta
    39061 gggaatacgg tcggggcgga ttctcaagga ggcagaccac atgatgtctg ggtttatgag
    39121 gcgctgtatc acgcaaggcg gttcatggca cggcttgggc cctggggcag ctatgagcct
    39181 gtgtgtcctc ttcgcaggct gtggcggcta tgaatccaat ttcagttgta aggggtatcc
    39241 agatcaagcg acgtgtgaat cagtctccga agcctacgag aagcgcttcg ctgccggcca
    39301 gaaggtgacg caatacacga aagaccaaaa ggacgcctca cacgacacca gcggtaattc
    39361 agggcctggt caggccccgt ctccgatggt cttcagcggc aaaccggaca gtgctgtagg
    39421 taagccggtg atcacgccgg cctcggccct ccgtgttacg gtatttccct ggaaggatac
    39481 gaaaaaacgc ctccacgatc agtcgcgtca ctatctcatc gtcgacgaac cggactttat
    39541 tttcgggcat atgacgcagg gtgtgagtcc cggatcgagt tcgtggcatg gaaaagattt
    39601 gtatccgaga atggggcgga tggtcgagaa acgagacgga aagaggaact ccagtgggaa
    39661 cgcggcggtg aacgccatga cggagaacat tccggaagca gggcagcgcg cggcgccgat
    39721 gcccgtgaat cctcttggtt ctggcggcat catgccgcag ggctttccgc agcttcccca
    39781 gtccggggga gcagccaatt acctgaccga tgatggccag ttgccacccc agtagtggaa
    39841 ggaccccaga ggagcgaata tgtcgacgat ccttgagtgg aaggcaaagc agctggtcga
    39901 gcggacggcc atcagtgatt ggttgcccta tgaggcttgg gatgacacca accaggtcta
    39961 tcgcttggat gatgggcgca tcggtgtggt gtttgccagc aagcctctac tggggttgtc
    40021 ggaagagtct attcagaagc tgacgaatct cttcgagtca gacctgccga tcggaaccgc
    40081 gtttcaattt atgctgcatg catctcccat catcgagcct tatctggacc atcacgttgt
    40141 gctcgcgcaa cgggggcagg caggggaacg ctatgtggcc gatgcgcgga agaccgccga
    40201 gttctatctg catgctcgag acacacagct gacgtccaat ccaccgttac gcccccgaga
    40261 tttcaccgtg tatgtatccg tggccttccc gacccaggag acgaccgcgc aggggtggga
    40321 agatgaacgg atacatcaag cggtgtcggg catcgaggga cagttgaaca ccttgggatt
    40381 gctgcctgag cgggtagggc cactgcaatt gttgaatgtg ctgcatgtgc tgctgaaccc
    40441 gggccacagc tgggagagtc ggccgccggc gtacagcgat caactgccga tacgggatca
    40501 ggcggtccgt ctcgatacgg cggccacgct ccgcaccaag atgattgagt tggacgggaa
    40561 gtttctcaag acgctcaccg tacagtcatg gcctgtacag tggcatggcg gcaacaatcg
    40621 cgaattgatc gggagcctgg tccggttcac cgatcaaatc acctgtccgt ttttcctgac
    40681 gttgaatgtc ttgaaatttg atcagggcaa agcgaaaggc aagttgcgaa agaagcacgt
    40741 cgtaatcaac cagcaagcca gtgggtttct tctgggtctg attccctccc tcaggttcaa
    40801 attggaccat ttcaacggtg tgcaagcgca actggaaaac ggaagacagc tcatcggatc
    40861 ctacttccaa gtcgtcctgt atggggacac cccgcgtcac gtggaggagc agacagggac
    40921 tcttcgagcc ctatatcgtg ccaaggatat cactctgcag gaagatcact tcatcgggtg
    40981 gaaaatattc atgacggggt tacccctcgg cttaccatcg gatgacaaag ccctcatcga
    41041 cggactcaga cgcatgaaga cctaccacac cgaggtcccg gcgcatattt gccctatcgt
    41101 ggcggattgg aaggggggcg gcgctccagt ggtgctgctg acatctcggt caggtcaact
    41161 tatcaccatg gatgtctttg ccaatcaaca gacgaattac aacatggcta tcgcggcgac
    41221 gtcgggggca ggtaaatcgt tcttcatgaa caattggatc aagagctact tgggcattgg
    41281 tggccaggtg tgggtcatcg atgcaggctt cagctacgtc aaacttgtgg agttgctcaa
    41341 ggggcaatac atccagtacg gagccaacgc tcaacgcctc tgtttcaatc cgttcagcaa
    41401 gctggtgcac tgggggagca gtgctggagg cgatgacgat ccgagtgacc gcgcggacga
    41461 attggcgacg ctcaaagcgc tgcatgcgca aatggcttcc ccctcgcgtc cgctgtccga
    41521 tgtcgagctc tcgttcatcg aagaagcgat catgcgtgtg cttgaggtgg aagggcgtga
    41581 gggctgtccg gattcggtgc accgagtgtt gaggggcatg acggatcctc gggccagaga
    41641 cctggcgcgc gtgttggcgt cctacgcgaa gggcggcatg tactcccatc tcttcaacgg
    41701 cacgaacaac gtcaatttcg agaacgactt cgtggtgctt gagcttgatg ggttgaacga
    41761 gcagaagcaa ttgcgatcgg tgatcctcct acagatgcag atgaatattc aggcggtgat
    41821 gtacaaaaaa gagaaccgcg gacggcggaa attcgtcatt ctggatgagg cgtgggattt
    41881 gttgtctcag ggaggtaata ccgcggcttt ttttgagacc ggcgcgcgcc gagtccggaa
    41941 gtcgggtggc tccatgatca ccatcacgca gggcatcaac gactactacg acaagatgcg
    42001 ggatgtgggg cgttatttgc tcgaaaatgc ggagtttgtg ggactgctca aacaaaagac
    42061 cgagagcatc gcggcgtttc ggaacaatgg gcgcattgtg ttgtcggaga tggaataccg
    42121 actcctgtcc tctgttacaa aaaccacgga gtactcagag attttcatga tcaccccatt
    42181 tgggcgaggt atttgcagac tgactgtacc acgggaaacg cagttgttgt ttacgacgaa
    42241 tccggatgag ctggcgctga ttgatcgggt gaggaaagag gggccaaagg agctctccat
    42301 cgatgaagcc attcaatgca ttatcgctgc tgaacgtgct caagcgggcg ccgacaatcc
    42361 tcgagtggct tgatcggcat cggtgggtgc atgtggggtt gatgctgttc tgcgggacga
    42421 tcattgctgc cggtgtcatc gctccctggt atgaagttgc cgctcgcatg agcgggagtt
    42481 ggccccacca taatttcttc ctcattcaaa aaggtcaatc cgtggggcga gggagtcttg
    42541 tggcgttcat catgcagcaa gactatgcgg aacgtgtcca gccgggccgc ttacaccgtg
    42601 actacgcgga cgtgggaaag cggtggatga agcgcatagt cggagtgccg ggtgaccaca
    42661 ttctagtcca agataatgaa gtctatatca acggacaatc ggtggggcgg ggaatcggaa
    42721 tcgatcgcta cgggcaacgg atcgacctag ccacgctccc ggagactatt cccgaagggc
    42781 aatactatgt ggcgctgcca cacccgcgat cgtttgactc tcgttactat ggcctgattc
    42841 ggcaggcgga tattctcggt acggtgaccc cgctcatcta gcgaggtcgg taatactcca
    42901 tacagacatt ctgatatgga ggtaccgtga aaggatcgag tgttatcgcc tgtatggcag
    42961 tgaccgtagt gctctccctc ctgagcatcg gatcccccgc gctctctgaa tcgacaggcc
    43021 gcccgagtaa accgtcccct gaggaaatgg ctcaggacat cgcaaggtac tcgcgccagg
    43081 cgttacggca ggggcgcccc caggaatcgc cgaaagagat gcgtcgcgac ggactctacc
    43141 ttctgctctc cttctcgtta ccggacgaca ccctcaaaga ctacctgcgg gaagccaaac
    43201 tgcttggcgc gaaggtgctg ctgcgcggac tggtacagga gtcgttcaag gttacgcagg
    43261 atcggattaa gcgggtgctc ttcaccgggg aacgcccgga tgactccctg ctggtcggaa
    43321 tcgggatcga tccggtgatc taccggacag tcggtgcagg agaggttccg gccctagtgt
    43381 tcgtgaagga cgagaagttc atggttgcga gtggggcatc ctcggtcgca catctcctgg
    43441 cgctgttgtc acaggagcag gcgaggttga agccatgggg tgaatggttc gagcgccggc
    43501 atcgagggtt tctccagggg ggaccgactg aagaagctcc gccactgctt ccgaccatcg
    43561 aacggagtgt gaaggtgtgg gccgacgcac gtggagccga cattgcggag cgggacatga
    43621 ttgatgtgat gaaggagcga gtggcgaacg caaattggcc ggacattcaa cgccgttccg
    43681 gcgatgccct caaacggcat ttcgccaagg ggccagggct ggccctaccg catgtcgaag
    43741 aggccagagt ggcgttcgtc gatccgaccg tcgagtaccc cgaggatatc aaggatccca
    43801 ccacgggcac ggtgctgatc aagtccggca cgaagatcaa ccccttcgac aaggtgcggt
    43861 ggattcgaac cctcgtgttt tttgacggca ccagtcccgc acagatgggt tgggtgcaac
    43921 aatatttgag ggagcatgac cctaagttcg tgaaactcat catctctgac ggcgacgtgc
    43981 agaaagtaat ggagcaactc catcaacgtg tctattgggc gaatcctctg ctcgtcagcc
    44041 gcatgggggt cggagcggtg cccagtgtgg tctctcagct aggccgaaat ctgcgggtgg
    44101 aggaggtggc gattcatgac taggtcctcg atgcgaggga tccggcaggt gttcttgctg
    44161 gtctgcctga gttgtgtgct gatcggcgtg gcgacgctgt ggccgtctgg gacggcagag
    44221 gccgtgtgca caatcggaaa ccctgtgttg gcgaatagtc tcgcgacgac gtgttgggaa
    44281 tgtatgtttc ctatttctct cagcggagtc acgttgttta acccgggaga agactttacc
    44341 gccccggccg tcggtccagg ccgcgcccct tttcccccgc agttgtgcgg gtgcgtttgt
    44401 cttgggccta tctgcattcc tgggttaccg ctggggatct gggaaccgaa gaatctggtc
    44461 gaggcggtac acgatcccct gtgtttcccg acgctcggcg tgtccttggc cgggggcttc
    44521 agttacatcg ggcgaggcat ggctacgacg cagatggact ccgaactcaa ttacgcattt
    44581 tttcatgtgc attatttcat ttttcccctg tgggccatcg tcggcatcgg attggacatc
    44641 gcatgtctga atcctaccgg gatcgcagac gagatcgatt tggcgtatgc ctccgagatc
    44701 gatcccttgt gggacgatga tctgatttca ctgatcctct ttccagaggc cttggtcctg
    44761 gccaatccgg tgtcgttagc agcctgtgct gccgattccg tggctgcagc ggttggcttc
    44821 ccgattgatc cgctgttctg gtgtgccggg agctttggat tcatgtatcc gccgaccgga
    44881 catgtctcgg gagcggatgg agacctcaag ccggctgccc tgtcgatgac acggttatta
    44941 gccaaactgg cccgtgcggg gacagagttt tggacgtccg ccaatggccc gttgctttgt
    45001 gacgacgtta cgacagctct cattgtgaaa agccagtaca agtttcaatt actgtggcct
    45061 attccgaaca ccggaattcc tccgccgtgc tgtcagcctc tggggcggac actcatgatg
    45121 tgggggctcg gcaaaatcgt gccggccgtt ggcgaggact ttgtgtggct gctatggaaa
    45181 cgacaaaact gttgcttgct ctagcgtggt gctctgtgag cgtctgctcg atgggggggc
    45241 cgaccggtgt tgcgagggcc gctgatcctc ccggctctaa gacgtttatc gatcatccca
    45301 ggcagggatg gttcttttat caagaccctc cagccgaggc tgaggaggac gcggaagaga
    45361 gtcctgtatc cgtcacgatt gacggcttac cccctggggc ttggctggag ccgtcgaaat
    45421 accggacgtg gttcaagggg cttgcgatgg atggagtcaa gttaaccgcc ctcccggtga
    45481 cggtgttgcg ggagctggtg tcggccaaaa aggaacgcgc gttggacgat ccctcggtgg
    45541 agaatgtgac gagttacatc aaagtccaaa aggaagcgta tgaccgctcg caacgcttca
    45601 ccgatgcctg gcagatcgcc atgtacacgg accccaagct cgactatgcg tcgcaacatc
    45661 ccacgtccac ctatgggcat agcgtcgaat ccgagatcaa gcgaaacacc gaagagcagc
    45721 tgctggcagg cacagccgac cgggtcggac tgttcttctt cttcacctct acctgtccgt
    45781 tttgtcaaga acagtccaag gtattgaagg tcttcgccga tacctacgga ctaacggtga
    45841 aacctgtgtc gctggatggg gtgggattgc cggagtaccc gcaacccgcc atcaacaacg
    45901 gcatggcgga aaacgtgggc gtgcatatgg tgcccatgat ttatctcgcg attcccgagg
    45961 aaaacttctt aaagccactc ggggccgggc tgatgacgaa tgcggatcta cgggagcgat
    46021 tgctggtcct gttgcggaat cgaggattgt tgggcgagcg accgtctcat ggatagagga
    46081 cacacgatgc gatgcaaacg gattctggtg ggactgtgta tgtgggccgt actggcctgg
    46141 cctcccctgg tgcaggcgca atcgatgaat gatgccctca cgaacatgtt cagctcgtgg
    46201 ggtgtcggga tcacgagtcc tcccggtgcc tacgagagtc aacgtcgagg ttacttcagc
    46261 ggcggtgggg tctcggttcg tttgtggcag gacccgatgc ggctgtggtc gattgcccct
    46321 ccgcgattga gcgtgggctg ccaaggcatc gatgtgtatc tgggctcctt ttcctacggc
    46381 aagctggatc ggtacgtcca gttgctgcag caaatcggga ccggggccgt cttggggtac
    46441 gcgttccagc tggcgatgaa agccatctgt gaagactgcg cggacgtgct caataagatc
    46501 gaagccgctg ccagagcact caacgccgcg ggacggatcc aaccctgtca aacggggatt
    46561 gaattgggta aggcgctggc cgggaacgaa gcctcgaaac agaagcttgc gagtcggttc
    46621 ggcgatgcct ggcagaagat gaaggaggcg gggggcgcca tcggagacgt gtttgaggac
    46681 cgcgatgcgg tcaagaacca gtcgaatgcg gatgcggcct cagctctgaa gggcacggaa
    46741 tacgatgtga cgggtaatct ggtgtgggat gttctgacgc aggccggcct ggatcagaat
    46801 ctcattgtca tggtgatgtc ggtcacaggt accatcattg tcgggaacga cggcgatgtt
    46861 caaacccgcg atccgacgat gacgttcgaa cagctggtcg acagccattt gggggacgtg
    46921 gtcaaaatat ttaattgcgg gggcgattcc gaatgtttga accccacgat tacggatgcg
    46981 accgatatcg aaggattcga aagtcgtgtg tatacgtcga tgagcaacct catcgaagac
    47041 ctctactcgg gctctgcaat cagtgcggcg gatcaacaaa tcatcaacat gacaccggtc
    47101 ccgattctga ccatgctcgc tgattatggg cggccacggg atgtcggcaa tcagattgcg
    47161 cgcttgtcat cagaagtggt ggctgcagac atgggatatc aatgggtgaa atgggcggca
    47221 tccgaaacat cccggaacgt cagctatatc caaaaggtca aaccagaatg gccgggcaat
    47281 ctgcaagatt ttcaggggcg gctgcatcaa gttttgaggg gggccagtga cagtctcgca
    47341 aagcggcaac gcatggtgaa taacatcaac cagctcatgc agttgacgaa gacgcagggc
    47401 gaaatgcgat cgctgcggta gtcgtcggag gaagcctgat tgcgatgtga ggggagagga
    47461 tagcggacca tgtggacgat ctataccttc ggcaatggcg atgtgttgac ccagattctg
    47521 ctgggcatcc ggattatgat gaccaccgga cgattcgaaa gtctcatgga gctcgcgctc
    47581 ctggtctttg cgatgttcgg actcgtctat tttgtgttca atcggcggtt cttggtcccg
    47641 ctggtcgttg gggccttttt cattctcttt gtcagcgttc gaatcacggt ggatgtgtcc
    47701 gtagaagacc aagtcaaccc cgatgttccc gatcaaatcg tcaacaatgt cccgctggcg
    47761 atcgcgttgc cggcatacat ctcggggcaa gtggggtatt acaccaccca gctcgtcgaa
    47821 gcgtcctttc cgatgcccgt ccaatatacc cagggacaaa catcattcaa tcgcccgtta
    47881 ttcgatctgc agaaggtgct gaatgcgaga ctgcaagact cggatctggc tcgcaatacg
    47941 gatacttatt ttatgatgtg cgtgtttcgg gaggttggac tgctacagaa gaacctcggc
    48001 acgctgagaa attctccgaa tctgctcaat gatgtcggag ccatgaacaa tgcactcacg
    48061 gcgctcgggt atacgggtgg tacattggag gcggctccgc gggtctgtcc ggatttctat
    48121 agttcgctta tcctcccagg atacaccagc ggccagcctg actacgaagg ggcgatgcgg
    48181 catttgcgga cgcagttgca gctcgatccg gccaccggca atgaggaagg gctcaccgag
    48241 gatattcgag cgaatctctt gttgtccgtc gggcaatccg ctcgagatat gatcaacaat
    48301 gtgctgctca ttcatgcgtg gaaaaacgcc gaatccgccg atgccaaacg tcgcgcggca
    48361 actgcggaca ccgtgctgtt gcagcaggag gcgatccaga aggatctgaa gttccagagc
    48421 tactcgaagt cctatgtcgc gcagaaggtc gtgccgttat tacggaccat cgtggaaggg
    48481 gtggtgtaca tcatgacccc gttccttctg gtgctcgcca tttcgcccgg catgtcccgg
    48541 ctgatgggca cctactggcg gctgttcatg tggctgcaga cctggtcgcc tctgtatgca
    48601 gtactgaatt tcgtcatgtt ctgggaagcg cggagccggc tgggcgcgat cttgagttca
    48661 aacggagtgg ggcagtccgt caactatgcg acgttggacc gaatcaacga acatgtcgcc
    48721 atgctgaact ccacggctgc cgattatgtg tggctcgtgc cggcgatcgg gtttggactg
    48781 atgtggggtg gcagccaggt gttgggatcg atcctggcgg gatcgcgaac ggcggaaact
    48841 gtcgctgggc aagtgggcgg gcagttctct cgtgggctcg gtgccaattt ggaggaaggg
    48901 ccctcctatc gacacgaaca gcgcggtgcc cagttcgggg agatgatcgg ccatgacgtc
    48961 gagccgcaga tgaccgtgcc ggccggcccc ggtggatttc gtgtcgatag tcaatccgga
    49021 acgagtgaga ttcacgactc ccagggtggc atcaccagta tcggcgcgaa tggtattcaa
    49081 aactacaaag gcccagaagg gcagtatgcc atggattcga aggggcacct cctgagtggg
    49141 gtattccgtc acaagatgac cgatcctcag tccgggaagc aggtcgatgc acaaacctcg
    49201 gtgttcgggt cgatggtgga gcatcgtttc gatacgatgg gtgaggacgg cgccagaaag
    49261 agcgtgctcg tacaggaaaa tcaggacacc ggagaactcg tggcgcgtac ggaacaatct
    49321 gttcggaaag gcttgtccga gacgcgtacg attgccgacg atggaagtca gagtttctca
    49381 cgatctggga atgtcccgct gtttctggaa gtcgcgggcg agacacgtcc cgatgccgga
    49441 tttgtccaaa tgatggggga gcgtgggcca ggagagcggg cagacaccat cacgcagtcg
    49501 atgtttcaga gcacgatggg ggcgaagcaa tcgtataccg gccggttggt cgaacgggat
    49561 ggacagtttc attttctggc gaccgagggc ggggcgatcc gaggatttga caacaaggat
    49621 acggaagccg ccgtccacag ggaatcgttc gtctcccctg acggctccaa ttattttgtg
    49681 gagactgggc aagcacaaca gatggtcttg gggaaggatg gcgtgactcg gccgatggag
    49741 ggatatgtca gggcctttgg gtcagtcgat cgctcagacc ctgcccatcc gcgagacatc
    49801 tactccagtt acagtctgac cagtgatgag ggtgggcaca cgcacacggt gacggggaca
    49861 ttgggtaccg atgcatcagg acgacagttc ttggtggaag ccacggaaca cttcgagtca
    49921 ggcacgagcg gcgtcgctca cgacacccag acggtcggct cgtataccct gagcggcacg
    49981 ttcacggcat tgagccatgg ggaagccaat caacctggag tgccgacagc cttcttcggc
    50041 tcggcgatcg acaatagcaa gccagggtcg ccggcgtttc aagccaatgc gctgctatac
    50101 gacggccagg taagcttctt tgatgggcga gagggaggga ccaagagtat ttccggggaa
    50161 cgtaatctga cggatggcac gcatttgtca ggtcagttca cccaattgaa tacgatggga
    50221 caggacggcc atcaaatcga gatgtttcat ggatatgctc agcaacctgg agcaccggcc
    50281 cgtgatgtaa cagggctgat tgataatggc aaccttgtgg cgtttaatgg cacctctggg
    50341 tctcacgcca gagacattgt cgaaaaagga tctggggtgt ctggtcggca atatgggttc
    50401 caagataccc tgatggctcc agggggcaca cattccgtaa gcacctttga gggcgtgtct
    50461 gtggacgccc aggggcgagc cttcaaaaac tcgtcagttg agttggatgg ggtccgtgtg
    50521 tatagcgatc agatgagagg atcgcgccag atgaccgtgg aattcgagca gtccctacga
    50581 gggtacaacg atgaagtaca gtcgatcgat aaagagtcag gttggcgccg gatcaatgac
    50641 gggcatcgcg atatggatgt atacgccaat ctctactacg gtccaacaag cagtgagacg
    50701 ggcgagcgta agttactggg cgggacgatt accaacgtga ccgacaacac ctattccacc
    50761 ttcatgaagg acggtgaagg caatgaggtg tgggggattg ccaggtcttt ggaagatcca
    50821 aacagcgagg ctatgagcgg ctctttcgat cagacactca aggtcgtggc tgccaagaat
    50881 ggagcggtag acacgcaagt ccttggtccg atgaaaagtg atggaggcca acgcgaggtc
    50941 ttgtatcact cggtgttagg cggattggac tcgcagtact ttaacaatga gcgcaagtca
    51001 ggcgtcttca ccgtgcctga tccaatgcat cccggacaga cgaaagagtt acaagggacg
    51061 ttctactata gtcctcaatc tggccagttg attgcgtccg aagtcacgga tgtgcaaaca
    51121 ggaaaggttg ggcaataccg caccgatgcg caagggcaag aacacttcca ggtggtggag
    51181 tatacacagt cgcctgacgg cgcgagcgtg attgcaagta ccagggagct atcgaagcat
    51241 gagtatgcag cccatggatt tgcggtcaac gacactctcg acagcagcgg gaatgtgctg
    51301 agttcgtccg gtaacaaggg agccgatttt catgacttca atcgcgtgca gtttcatcat
    51361 gatagtggag cgaatttgac gattacccaa atggcgtttg cggccaaagg caccgatatt
    51421 accaacccca cgcaaacgga cgaggcgatt gcctatggcc tcgaatttgg tcggattgga
    51481 atggatgggg cttcgcgata tttgatcctc aagggacgaa tggggaagtt tggtggcgga
    51541 gcggctgggg ggacaccgtt tcagtcaggc ggtggacccc tgccggatgg acctggtggc
    51601 ggtgggggcc caagtggtct cttggactcg catcaaaata tgggtgcctg gtggaaagag
    51661 tattccggcg tgatggataa tgctatatcc tttgcgcgta gttctgtgga gcatttggaa
    51721 aagaccggcc gcgcacaaac aatgtctccc gaagaactac agaacttcgc tgccaatgcc
    51781 gcctataatg cggtacgcac atcggccatc ggcatgttgg gtgaagaggc gtcgaatgcg
    51841 tttgggacca tgcctaagtg gcaggtaggc caagagtcgt tgttgaaggt tgagcgaaca
    51901 cagccatcgg ccccaagcac tagtaaagag aagtaggtag cgaatggttt tgtccagagt
    51961 ggaggtcaca tgcggccgta tcagatagcg ctagttgcgg tgatggtcgc aatcgttgtc
    52021 agtcagtcag gtggtgcgag agcggagtcg ccaaaagatg gatggttagg ggcgttcgtt
    52081 ggctcggaga ttccaggagt accaatcaag cgctcaacta tcgctgttgg gtcggagcaa
    52141 tttagtccct cctccagtgg gagttctctg gctgtattaa atgaagttgt agaacagtgt
    52201 cggggaagca gaaatgggcg agcaatggtt aatattagga tcgtgaacac tgtcggggaa
    52261 acctctgaac ttcaggcaga caaaaagacc tataggacct atccagggtc attgttaatc
    52321 actgtgtatg gtgattgcgt gcttgaggtg caggatgcga agtgagactg ctaagagcag
    52381 gactgatatt ttgcgtggaa gatggtttgg agatagtcct taaacatacg cgcatcttcc
    52441 gtccagtcac ggctaaagtg caacacgtca tatctgattc gttccgcctt ctgaatatcc
    52501 acaaactcta gaatggccgt ctcctgatcg gccgctccgc tcctgatggt gagtgccaca
    52561 gaggcgggaa tccattaccc aaaaagaaca gctgtaaacc ccctctcgtc tgatccggtt
    52621 cgtctccccg acgagctgcg tgactcccac cgtccatccc aagccatcgc tgtggagtga
    52681 cggtgccact cgtggcggct ctacagccgt cgttgaggtg atgtcgcgcg attctttgaa
    52741 cgtctgcaac gtggtcggcg tgaagacggg ggcacaggat accccggtga ccaatccgag
    52801 caggatcacg ctgatcgtcc ggcaagatga cagcgatgta agtgccacga gggcgcggac
    52861 cttctctctg gacgatagcc gaagcggacg gggactgttc cggtaatacc tgttgggcat
    52921 agttgtgaga ccgggtctcg aactacaggc acatggcagg tgcatacaca ggtcaaaaaa
    52981 ctatagcgca ggcgagtaac gaatggtgca ggtgggagac ttagtgatgg ctcgggtcat
    53041 tcggatggat ccggggcaca gcgcatatct gctgtgggcg gattccatcg ggcggtacgc
    53101 catcctgccg catcagcatg ccgatcgtca gtacaaggtc cgcgattccc tgatgggggc
    53161 tgtctataag gtcggtgacg agtttccgat gctctcgcag cgatcgatgc actatttccg
    53221 ccgtatcgcg gagttagtgc tggctccggt cttggcggat gaccatgtgc atatcaagcg
    53281 cgtggcgacg tctcgagccg cgtcgtttgt gaaggtggct gtcgacacct atcgctcggg
    53341 agaagatgtc atcgcggcct gcaagcccct gttgtacgag tttcgtacct acacctcccg
    53401 cacgatcgct ctcgtgaagt atcactcgga gttggaatct tacattcgcg aggcgttagc
    53461 gcctgctccg agtcggtcgg tgcgtcgagt ggatgtgtat cgggaggagc accaagcgcg
    53521 agtgatcgtc gagccgggca cgattgcgca gtttcttggt cgcaagggga tgaatgctgc
    53581 ggtggctagc aaattgactg gatatggact ggtactcgtg gacgaagggg atctgggtaa
    53641 ggtgggaggg gcgtaatcga ggaggtgagg catggctcat ggggtggacg tagaacagca
    53701 accggggatg gtacggcgtg agggcccgtc tcttcggagt gcgtctccga cgaacggacg
    53761 aaggcccgat cgggcggaag agaacaggaa gcggatggaa gatccgaatt cgattctcct
    53821 gttaccacag acaaaggcgg ggatggcctg tgtgtccctg ttgtacatgt tcgacaaggt
    53881 tgtccatcgg cttcggcggg cagcagggtc tcagctctcc gttgagcaag tgcgcaatga
    53941 gttggctcgt gtcgagcaat gggtggcacg ggcaaagggg ctcctacgag aacttggagt
    54001 gggcgagttc gagttgcttc cccaggagct gtatcccgat ttgaaagagc ggagcgtgat
    54061 ggcggcgagg cgaaatgcgc gggtcattac accacgggtg ggagacacgg tgagactggt
    54121 gccggtgatt cgcgcactcg atagcgcgct caacagtatt cgtctccgag cggaagatct
    54181 cagtccgtat gtgaaacatt ttcaggccgt cgacgagctc gtagtggccc tgcacgatgt
    54241 catcggtcat gtcgcccgcg tgacggtgac ggagtatgaa ccgcggggcg cggtgaaggc
    54301 atttctccag gaagggaaag agagtcagtc aactctgtcg taagaaagga gcacggtatg
    54361 tggccacgca tggcggtcgt tggtctcgcg gtgttgtccg gttgcgtcag cgccggggaa
    54421 tatcaggact tggaaaccaa gtaccagcat caactcgcag tgaaggaagt catggagacc
    54481 gaacatgacg agctgtccca ccgagtcgat aacgtgtccc aggtgtatcg gcatgtcgcg
    54541 caagagcaaa tggggttgaa ggctcaagcg gaaacgctgc agggggagat cctgaccgtg
    54601 aagggcgtgg tgaaagatac ccagagtcag tacgaggccc agcgggcgca gtttgcgcag
    54661 cagacacaac aactgtccgg tgtcgacgcg cgtctgcaaa atattgcggg gaagatcgaa
    54721 accctcaccg aaacgacggt cgccttagcc aatcgcttcg aacgtgtcga actgtcgata
    54781 gggaaactag ggaagtccct gcaggcgcga gggggtgctc ccgaggtctc caaaacgcgt
    54841 gttcaggtgg gtgagggaaa gtcgggaggt gctcagaaag cggaccctgt cgccaaggcg
    54901 ggcagtccga atatggaggg gagtgccggt gcaggggcag tgggctccgg tagtgaacca
    54961 ggtgggacga gcctggcggc cgctccgagc ccggtggcgc caaccacggc cccggctaaa
    55021 ccggatgttc cgatggttgt ttctccgaag gtggtcgagg ccaagttcga accggctggt
    55081 tccaagcccg atgcggacaa agggtggttg cggcgttttc tggatggctt ccgtgggggg
    55141 aacgggcaag tcgcggaacc tgtgtctact ccaccgactg ccggttcagt aggaaaagcc
    55201 tcacctggac gcccccttcc tccgtcggtc gatggcgagg tgatggccgc gccgatgaac
    55261 acactgacga tcagcaccga gggggatgcc ccgaagaagg ctgaggtgtc accgattgat
    55321 accgagaagc gataggcagg aatgaaaatt ctcacggtag atgtcatccc tgggcatgcc
    55381 tatcggtact ttcaggcgtt gattcagatc gagactgtcg ggatcgcgtc ctggcgggat
    55441 gccgtggtcc gtttcacgga tttctggggc gggcgcgcga agacatacga cagcccgatc
    55501 gtccatgcga ctcagagcat ggtggatcgg cttgcgcaaa gcgctgcctc cctgggggcc
    55561 gacctgatta ttggattcga cattcagatc catcaggtga ccgcacggta ctgggggtgg
    55621 gggatggcgc aaatcgtcat gcgcggaacg ccgatccagt ttacagatcg tcacgcgatg
    55681 gggacgatct ttgcgggtga atcggccccc ttcgtcgcga gtggcgagcc tccacaacat
    55741 ccggcggacg ggaatttcca gggagaagcc gcagggatgg ccgagatgcc ggtgccatcg
    55801 ttggatacgg ctcggttcgg tacgcgggta tagaggaggc tgttagcgat gaaacgcacg
    55861 ctcacggggg ttttccttgc ggtctgtctg gcgtgtggtg cgagagaggc ccgtgccgat
    55921 tgtagcggga ttgatgatgc ctacctcaaa gcaaagtgcg aggtggaggg gcaaaagtcc
    55981 tcgggcttga ttggtggggg gattttggcg ccgaacatga caagagtacc gcggtactca
    56041 ggaacgccgg gctgtgtcac ggcaggatgt tccggggccg ctgaagagaa gtattacgat
    56101 gatcctggaa gtttgagtgc ggctggcggc acggccgccg gtagcgatga gaggtacacc
    56161 caaatacggc agagcagggt ggaccgtgat ggatgggact tacggacgag cggtgcagtg
    56221 acgacggctc aatctgcggc ggagacccta ccgccggatt ccatcacatg cggcagccag
    56281 aatagttcag tgccgttttg cgtggatacc aacactcccc caaatcagaa tctggcgttg
    56341 gcggcaacct ggttatcgat gacgaagaat gtcgaagagg attgggatcc ggaccggctg
    56401 cggatcttca cgggcaaaag gagtacctgt gatttcagca cgatcgggcg ctccctgatc
    56461 aattgctgtg attcggaccc cgacaaattg atagggaaat gctcggatga ggagatcgcg
    56521 ctggcgcgtg acaaacagga ttggaaggcc cgtttgattg gaacacattg cgtggataag
    56581 gggccgtttg gtgtgtgcct ccgcaaagaa gaggtctact gcactatgaa atccgagctc
    56641 gggcgaatgg ttcaagagca aggccgtgcg cagttgggca tgacctgggg atcagcggat
    56701 gcgccccagt gtgacggatt tacg
//
LOCUS       DAOQPD010000019        50143 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_265_length_50143_cov_19.290329, whole genome shotgun sequence.
ACCESSION   DAOQPD010000019 DAOQPD010000000
VERSION     DAOQPD010000019.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 50143)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 50143)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50143
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_265_length_50143_cov_19.290329"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            62..1063
                     /locus_tag="PK063_06620"
     CDS             62..1063
                     /locus_tag="PK063_06620"
                     /inference="COORDINATES: protein motif:HMM:NF013706.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HMZ96756.1"
                     /translation="MKLVSFEVHTPVGIFRRIGAMRAGSIVDLNMAYARLLAEQRESR
                     PRRLADAQVPATMLEFLQGGASAMDAARRAFDFVAQDASLKGPSGETIIYNAADVHII
                     APLPNPASLRDFIAFEDHIAATSKRRGQPIPPEWYKAPVYYKGNHRTIVGPDYSLPWP
                     LNTQKLDYELELACIIGRDGIDVPERDAAQYIAGYTIMNDLSARDIQFQEMACRLGPA
                     KGKDFATAIGPCIVTPDEIPDLASLQMIARVNGEVWSQGRFGSIHWSFPQMIEHVSRG
                     EAIYPGDLFGSGTVGGGCGLELDRYLQPGDCIELEIQPIGILKTTIAGHNKRSREEA"
     gene            1060..1821
                     /locus_tag="PK063_06625"
     CDS             1060..1821
                     /locus_tag="PK063_06625"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96757.1"
                     /translation="MMPVVTKSSEAAIVETVERQRAMYDGSDIDVRMQHLIRDTPHPT
                     LSSWDIQRLLRASRAVYFDSHVEVVSGHHTEVYLRFESIGRFPDLVTIIASNMAEWIL
                     QTFHHDPPAGILTTSSDARLLAKRTCEILATHLPLRTVLTPFNPDTGKIGTEIISGTV
                     APGERFLSLNDVTTRGMCVSKLGKVVTDHGGQLAGMMVFARRDSGQFPFMDELTATYP
                     FYFGVDLDMPQWEPADCHACRDGKPLVSWRDLPAL"
     gene            1858..2859
                     /locus_tag="PK063_06630"
     CDS             1858..2859
                     /locus_tag="PK063_06630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HMZ96758.1"
                     /translation="MDQAGVAQDIKRSDLLEMYFYLRLTRSLEDRITALYRQGRIVGG
                     VYTSHGMEAIAVGYASALQSDDVIAPFHRDMGAFLIRGFSPGEIIAQYLGKQAGPTKG
                     KDGNVHMGDLKRGVIGFVSHLADNMPVAAGAALAFKIRGESRVAFAGTGDGGTSRGDF
                     HEAMNFAAVRKLPVVFFCTNNQYAYSTPVRYQMAITDVVERAKAYGMPGEIVDGNDVA
                     AVYLASRRAIAKARSGEGPTFLEFKTMRMHGHSEHDAATYVPRTLLEDWKTKDPILRA
                     EQLLMQLGYGDDSYFHEVGERAKKDVDAGTEFAEQSPLPEGRETLVGVFATQDEVLP"
     gene            2856..3854
                     /locus_tag="PK063_06635"
     CDS             2856..3854
                     /locus_tag="PK063_06635"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HMZ96759.1"
                     /translation="MTTATVTQEIQTTYVDAISQALDEEMSRDERVFLMGEDIGAYGG
                     AFKVTEGFLKKYGEWRVLDTPLSESGFVGAAIGAAMMGLRPVVEMQFADFISCAFDQI
                     TEVAAKNHYRWGAAVPLVIRAPFGGGVHGGPFHSECPEGWFFHSPGLKIVAPSTPYDA
                     KGLLIAAIRDPNPVLYFEHKFLYRRIKATLPQEEYIIPLGKADVKRSGRDMSLITYGA
                     MVHLALEAAEVLQQEGIELEVVDLRTLIPLDKETLYASVRKTSKAIILHEDNKTGGIG
                     AEISALLTEDCFDCLDGPILRIAPPDTPVPFSTPLEEFFLPKVSDIVAGARKLAAY"
     gene            3896..5065
                     /locus_tag="PK063_06640"
     CDS             3896..5065
                     /locus_tag="PK063_06640"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF012424.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase family
                     protein"
                     /protein_id="HMZ96760.1"
                     /translation="MATDIVMPQLGESIAEGTVVKWLIQAGGAVEKDQPLLEVETEKV
                     ALDVPSPAAGFLAEVMVQEGTTVPVGTLLARLETQPAAAGVVNRVGDVGVRARQEQQP
                     GEQHYSPAVKQLAREHGVDLTVVPGTGEGGRVTKKDLLDYVSTRQQPSGEPPRTAQAP
                     TVVPQPRETPEEIIPFTQMRKTIADRMLLSRRTSAHVTTFFEADFRGIDIFRTGRTLT
                     YLPFVISAVTRAMKDLPLLNASWRDQGLAIKKAVHIGIAVALDEGLLVPVIRHADQKG
                     LTQLAHEVAELAERARNKRLTPDDVLDGTFTITNHGGFGSLFSTPIIHQPQTAILGVG
                     SVQKRAVVIDDAIAIRPMCYLSLSFDHRIIDGATADRFMAKVKQHLQQSDWEKLL"
     gene            5062..6267
                     /locus_tag="PK063_06645"
     CDS             5062..6267
                     /locus_tag="PK063_06645"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006635 - fatty acid beta-oxidation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HMZ96761.1"
                     /translation="MTARHHAVIVSAVRTPMGSFNGGFSSIPSTKLGSIAIAEALQRI
                     QLTGEQIDEVLMGCVLSAGLGQAPARQAAIGAGLPHRVGAVTVNKVCGSSLQTVIMAA
                     RAIALGEAQIIIAGGMENMTRAPFLLEKARQGYRLGHGELTDSLIKDGLWDVYNQFHM
                     GNAGELCAARYQFSRQQVDDFAMESYSRAREAITAGSFTREIVPVEVPQKKGAPLMIA
                     DDEEPNRVDLSRLRQLKPVFQDDGVLTVGNSPSCNDGAAALVVMAEEEAHRLGLPPMA
                     RIVGYAGAALAPEWFTIAPIDAIRRLLKQTELTVSDIDLFEINEAFSAVSLAITRELG
                     LDAKKVNVNGGAVALGHPIGATGARILTTLLYAMEERDAHRGIASLCIGGGEALALLV
                     ERPRKIQHQ"
     gene            6293..7189
                     /locus_tag="PK063_06650"
     CDS             6293..7189
                     /locus_tag="PK063_06650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-CoA dehydrogenase NAD-binding
                     domain-containing protein"
                     /protein_id="HMZ96762.1"
                     /translation="MESRMTIDDITTVGVVGAGQMGRGITQVLATAGWKVLLVDVTEE
                     ALEDATKKIWQGVTKAVEKGALRGDQAGSAMAIIHPIRHMQRLREAQVVIEAIPEDPV
                     MKRALFAQLGQICEPSTLLASNTSSISIASLGMVSGRPDRVVGIHFMNPVPVMRLVEV
                     VRAIGTSEQTMRLALELVQRAGKTAVVCKDFPGFIVNRVLIPMINEAIFALEDGVATA
                     EAIDLAMVEGTNHPVGPLALADRIGLDTVLAICEVLHQDLGDPKFRPCPLLRKYVEAG
                     WLGRKSGHGFYQYGDQPVMHLT"
     gene            7221..8816
                     /locus_tag="PK063_06655"
     CDS             7221..8816
                     /locus_tag="PK063_06655"
                     /inference="COORDINATES: protein motif:HMM:TIGR00641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl-CoA mutase family protein"
                     /protein_id="HMZ96763.1"
                     /translation="MNERKSRFTSLSGLEIERCYGPDDLKGWSAEKDLGQPGAFPYTR
                     GCYPNMYRSRLWTMRQFAGFGSADDTNTRFKYLLDHGQTGLSVAFDLPTLMGLDSDDP
                     LARGEVGYCGVAISSLADMERLFDGIPLDQVTTSMTINGPAAVLFAMYLAVAEKRGIP
                     FERLGGTIQNDILKEYIAQKEWLFPPEPHLTLIVDTIAYCAAHVPKWHPISISGYHIR
                     EAGSTAIQELAFTLYNGLTYVEAAVKAGLEVDSFAPQLSFFFNVHNDFFEEIAKFRAA
                     RRLWAREMERRYHPKNPRSLQLRCHAQTAGCSLTAQQPMNNVVRTTLQALAAVLGGTQ
                     SLHTNSMDETLALPTEEAVKLALRTQQIIAAESETVNSVDPLGGSYVVESLTNRLEEG
                     ALDLFRKLDGLGGMVSAIERGFPQREILDASQRYQREIERQERSIVGVTTHREEDVRS
                     IPILKIGPEVEQEQVARLSDLRKSRDPFKMAGSLEELQEMAACHQNLMPSLIEAVKAK
                     ATLGEICAALKEVYGTYREPVVL"
     gene            8813..9655
                     /locus_tag="PK063_06660"
     CDS             8813..9655
                     /locus_tag="PK063_06660"
                     /inference="COORDINATES: protein motif:HMM:NF012955.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HMZ96764.1"
                     /translation="MKLGAFDIYPVTDGRFRLDGGAMFGVVPKVLWQTCCPADDLNRI
                     PLSLTCLLIRAHGKHMLVDTGLGDKENEKFRSMFAVERKPTLRESLSQHGLCRDDIHL
                     VVNTHLHFDHAGGNTATDGRSAVAPTFPKATYYVQQTEYDDAMQANERTRASYRRDNF
                     TPVAEANQWALLKGETELLPGVTAIVTPGHTRGHQSVKVESEGRVAFFLGDLIPTVSH
                     LPLPYIMGYDLDPVQTLDSKRWVLERACEEHWLLLFEHDPYVQAGYVSKTVDGKYALQ
                     EVTL"
     gene            9652..10059
                     /locus_tag="PK063_06665"
     CDS             9652..10059
                     /locus_tag="PK063_06665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin B12-binding domain-containing protein"
                     /protein_id="HMZ96765.1"
                     /translation="MTVAATPLRILIGKVGLDGHDRGVKLVARALRDAGIEIIYTGLH
                     QSPEQIVTTAIQEDVQAIGLSIHSGAHNSLFPRILGLLRERGAEDIVVFGGGIIPDED
                     VPRLKAAGVQMLFRPATPMQDIVEFVNGLRTER"
     gene            10073..11677
                     /locus_tag="PK063_06670"
     CDS             10073..11677
                     /locus_tag="PK063_06670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="HMZ96766.1"
                     /translation="MRVLDTSIRRDSDEFRRNQAHYEGLMADLQKHLEMVWAGGSREA
                     IALHKQRGKLTARERISSLLDPGSPWLELSPLAAFGLYDNQVPSAGLITGIGSVSGRF
                     CVIAANDATVKGGTYFPMTITKHLRAQTIALENRLPAIYLVDSGGVFLPMQAEVFADK
                     EHFGRIFFNQARMSAAGLPQIAVVMGMCTAGGAYVPAMCDENVIVQGTGTIYLAGPPL
                     VKAATGEEVTAEALGGADLHTRLSGVSDHLADDDRDALDICRSIIATLPRRLPKPRRN
                     HIDEPLYPAEDLYGLIPANPRQKWDVREVIARLVDGSRFHEFKARYGATLVCGFAQWM
                     GHMVGIVANNGVLLSESALKGAHFVQLCAQRRVPLVFLQNITGFMVGKDYESRGIIKD
                     GAKMVQAVSTAEVPKFTILIGASHGAGNYAMCGRAYGPRFLFSWPNARISVMGAQQAA
                     QVLVTVKEQQRAREKAALTDDERRRIIEATQRQYEQEGSPYFSSARLWDDGILDPTDT
                     RRVMGLCLDLAALAPVKDSHAPVFRM"
     gene            11697..12542
                     /locus_tag="PK063_06675"
     CDS             11697..12542
                     /locus_tag="PK063_06675"
                     /inference="COORDINATES: protein motif:HMM:NF012596.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="HMZ96767.1"
                     /translation="MRPFTTLMIESNGAIARVTLNRPDRRNAFDGQMATELREAFEDL
                     AHDPSIRGIVLAAAGSVFCAGADLQWMQSDGPASETPAMRDAHHLLRMFRAIDEFPCP
                     VIARVQGSAFGGGLGLLAVCDIVVATEEATFALSEPRLGLIPAVVAPFLLHKAGESFL
                     RRYGLTGETFCASTAQRYNLAHDVVPQSNLDDRINELSDALMQLAPCATKESKLLFHR
                     LRALSDKERLALGPEYNARARCAPEAAEGLRAFIEKRPPAWAQPRERKPQEATTSDDV
                     VLRHR"
     gene            12520..13467
                     /locus_tag="PK063_06680"
     CDS             12520..13467
                     /locus_tag="PK063_06680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HMZ96768.1"
                     /translation="MLCFATDETRRLPVRIIEVSPRDGLQHEAIFVPTARKIDLINAL
                     SHSGVTEIEAGSFVSPTAIPQLADSDEVFRAIDRLPDVTYSALVPNERGLERARAAAV
                     QKIAVFTAASNSFTRHNIKATVQESLVRFTPVIHGAKRDGMLVRGYISTALWCPYEGR
                     IAPKLTVDVMRRLLDLGVDDISLGDTIGRASPADIRGLLDAVMPHIEPTRLSLHVHDT
                     YGMAVANVLTAWEDYAITAFDCSAGGLGGCPYAPGASGNVATEDVVFALKASGATVAV
                     DEELIVDCARQLSAVIGHPLHSRLSQISRPRIGQPALKV"
     gene            13469..14287
                     /gene="meaB"
                     /locus_tag="PK063_06685"
     CDS             13469..14287
                     /gene="meaB"
                     /locus_tag="PK063_06685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0015819 - lysine transport [Evidence IEA];
                     GO_process: GO:0015822 - ornithine transport [Evidence
                     IEA];
                     GO_process: GO:1903826 - L-arginine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl Co-A mutase-associated GTPase
                     MeaB"
                     /protein_id="HMZ96769.1"
                     /translation="MNHVTAHPSFFRHDAAELARQVEAGEVRAVARVISLLENRDPLG
                     AAVLTHVAPSLNRALVIGITGYPGTGKSTVIDQLITAYRRLGEKVGVLAVDISSPVTG
                     GAVLGDRIRMQRHTDDARVYIRSMATRGHQGGLAAATRQAVRVLDAAGFGVILIETVG
                     VGQSDVDIMQVAHTVVAVVAPGLGDDVQAMKAGLLEVADIVVVNKGDREGADAALRDL
                     REWCKTVIRAVAVKGEGIAELIAVIAEHERWRDLDRPALHNRRGPSIDLGSRTG"
     gene            14319..15713
                     /locus_tag="PK063_06690"
     CDS             14319..15713
                     /locus_tag="PK063_06690"
                     /inference="COORDINATES: protein motif:HMM:NF015905.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmgE/PrpD family protein"
                     /protein_id="HMZ96770.1"
                     /translation="MLADRLAHYTQSLRFKDLPGDVVHEVKRRILDSLGCAFGAWTAT
                     PCRIAREMALAVKVPGGATVWGTNHKTLPDLATFANGAMVRYLDFNDTYLSKEPAHPS
                     DNIAAVLAAGETAHASGQLIIQALTLSYEIQCRLCDAAALRPRGWDHVTYGPLSSALG
                     IANVLKLTDAQTRQAVNLAGVANVALRQTRVGDLSMWKACAFSNAARNGMFAALLARR
                     GMTGPAPIFEGEKGFMKLVSGPFELPMLGGEAMPGGEPVPFKILKTCIKHFPVEYHAQ
                     SAVEAALALRAELLATEGKTWINKVADVEIGSYDVAIEIIGRDPEKWQPATRETADHS
                     FPYCVAVALVDGRVSMNSFSPKRLRDPRLHELMKKIHVVKLAELEHRYPTTMPTRLTI
                     RTSQGSTHSRQVDQPLGHPGHPLSDQEVGDKLRRLTSRRIDRAQLDRLLAFVWHLEDQ
                     TDIAAFMPLLRVRS"
     gene            15710..16648
                     /gene="prpB"
                     /locus_tag="PK063_06695"
     CDS             15710..16648
                     /gene="prpB"
                     /locus_tag="PK063_06695"
                     /EC_number="4.1.3.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046421 - methylisocitrate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019629 - propionate catabolic process,
                     2-methylcitrate cycle [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylisocitrate lyase"
                     /protein_id="HMZ96771.1"
                     /translation="MTFDHSSGDKGRRLQEIVARRTVAIPGASNALTAVQIERAGFDA
                     VYVSGAAVSAARGLPDIGLISLSEMVGEAGIIARAVAIPTIVDADTGYGPPSTVMNAV
                     REFERAGIAGMQIEDQEATKKCGHLEGKRLIPLGDMVAKISAAVKARHNRNFLIVART
                     DARTVDGLDGAIQRAKAYAEAGADMLFPEALLSPEEFGTFSLAIRNAGIHLPLIANMT
                     EFGRTPYLSVDEFQALGYQAVLFPVSSLRVAARAVEKLLSELKFFGSQRNWLDHMMTR
                     QELYDLIHYEDGTTSMRRSHEPDHAGTVNGEGSRPS"
     gene            16596..17774
                     /locus_tag="PK063_06700"
     CDS             16596..17774
                     /locus_tag="PK063_06700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046912 - acyltransferase activity, acyl
                     groups converted into alkyl on transfer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citrate/2-methylcitrate synthase"
                     /protein_id="HMZ96772.1"
                     /translation="MNQTMQEQSTVKAHDHPEYSPGLEGVIAGESAICQVDEGEAGLR
                     YRGYAIGDLAGRSSFEEVAYLLLFGHLPATTELEEFSRLLVRNRRLPQQVHHFVESLT
                     PDMHPMDVLRTGISLLGLHDPDAQDGSREANLRKSVRLLAQIPHLVADSYQIMADRQP
                     ATPVSHGSFAENLLSLVAGRRYGEIGAAMAEALNVSLILYAEHEFNASTFAARVTAST
                     LTDLHGAITAAVATLKGPLHGGANEAVAAMLIEIGRPEHVEFWLRDQLAHKRRVMGFG
                     HRVLRQGDARSAIIQHHAERLSDLCGDRNWYHIATTLDRLMLEEKGLRPNLDFYTAVA
                     YLLMGIPRGLSTPLFVCSRITGWCAHVIEQQEHNRLMRPRALYTGPAPKAYEPLERRT
                     "
     gene            17749..19467
                     /locus_tag="PK063_06705"
     CDS             17749..19467
                     /locus_tag="PK063_06705"
                     /inference="COORDINATES: protein motif:HMM:NF012711.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I adenylate-forming enzyme family protein"
                     /protein_id="HMZ96773.1"
                     /translation="MNLLNDVRDHIEQARDVSGRATDVPWASFAEFLRSRVYDPQLAT
                     THALTFCDDDRALRRTYTYAELGAIIERLAGVFHTRFGLTRGDRVATLLFNHDVTVLT
                     YLAAWTLGVAVVPINIEETPEKKRYILEQSEVSTVFCWQDGYEELCALQSDIPTLRQV
                     IALGDAGVLDNHRTGKKFHAHGAGRSLRRSPFTSGLDDHALIVYTSGTTGPPKGVILT
                     VANLLIDADAIASWHSFGLHDRLMCVLPIHHVNGIVVTLITPLYCKGSVVMNRRFKTT
                     SFWRRIHEEQVTSVSVVPTLLEFLLDADEDLTPYDLSRLGGLICGAGPLLKDTAARFE
                     HRFGVVIRHGYGLSETTCYSCFLPNDLTQEQHRHWLTGYELPSVGVPVRHNLMTVLDE
                     RGRTLPPATRGEICIRGRTVCAGYFKRDDANEAAFQWGWFRSGDEGFYLLDDSGRPFF
                     FVSGRLKELIIRGGVNISPLEIDDVLKTHQAVKFAMALPFENRYYGEEIAAYVVPKDP
                     ASIPSEADVLAHCRMRLPFSKQPKVVLFGDDVPYTSTGKPKRLELKARLAGRLAQYRD
                     TQFRDQ"
     gene            19494..21500
                     /locus_tag="PK063_06710"
     CDS             19494..21500
                     /locus_tag="PK063_06710"
                     /inference="COORDINATES: protein motif:HMM:NF012656.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HMZ96774.1"
                     /translation="MSTLIKGFERIEEARERLTGASFLAGLFDGRPDFEFLLTPPEPP
                     EERAAGMAFCKQVETFLRQEVDPDEIEREAKIPDAVIRGLFKLGAFGMKIPKAYGGLG
                     FSYTNYGRVLTLIASWSNILALTVAVPQSIGIAMPILLFGNEDQKRRYLPLVATEALS
                     AFALTEPMTGSDAANVRTEATLDANGSHFLVNGEKLWCTNGPIARYATLIARVPARRV
                     VREGQTTWMPVPEGQGADDRVHTAFILDMSTPGMQVRQRCQFEGCRGIENAHMTMQEV
                     RIPVENVIGEVGKGLKYALTILNVGRGISIPAICLGMAKQAWQPTLDRANGRVTFHKP
                     LAERQTQQIRLGDMAAHLFAMEALSMLVWRLADQHRHDIRIEAAVAKIFCSEHTIQFL
                     RDAQILFGGMGYETAASKMARGEAGFGIEQLVRDAEMYRIGEGATDILRPFIVREGLS
                     HHLDRAKPFYSGDLSILDQLKQLVKLGGFYGPWYLRHWVRHSLPTGSAFAHPQVRSVA
                     RYVERTSRRLAREIFYAMVRFQAAFQDEQRVQNRIESIGEDLLAMIATVLYAEQQTRL
                     EGRTTVWELAEAFHVAARKRITQRLREIRRHCDGVTAETGQQALKGYYPGLSDGIVHR
                     RLDDYRRKQAVSEAMPLAMASVSLDVKDRSLFAPVKAKAGERST"
     gene            complement(21513..22442)
                     /locus_tag="PK063_06715"
     CDS             complement(21513..22442)
                     /locus_tag="PK063_06715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HMZ96775.1"
                     /translation="MMTGISLDTILAWLITMSAAVGIASLRIGLVLAIGYVAIRFVRL
                     GLHQLERVMIVASDKQDQESGTAAKRAATLTGILRTIALSAIWAIIIIESLQLVGLDI
                     APILAGAGILGLAVGFGAQNLVRDLISGFFIILEDQVRLGDVAVINGTGGAVETITFR
                     TISLRDFSGVVHIFPNGGITTLSNMTKDWSAFVLDMGVAYREDTDRVVEVMRTVGEGL
                     RQDQAFGSLIIEPIEIVGVENFADSAVTIRARIKTKPAEQWKIGREYRRRLKKAFDAQ
                     GIDIPFPMRTLLMGETDQPLKVEVIAGLGLGKS"
     gene            22703..22778
                     /locus_tag="PK063_06720"
     tRNA            22703..22778
                     /locus_tag="PK063_06720"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:22736..22738,aa:Met,seq:cat)
     gene            complement(23082..23336)
                     /locus_tag="PK063_06725"
     CDS             complement(23082..23336)
                     /locus_tag="PK063_06725"
                     /inference="COORDINATES: protein motif:HMM:NF016876.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HMZ96776.1"
                     /translation="MTPFKNVKLTKSAAKELRPIPQKFRAAVQAALDALAADPLLGTA
                     LLPPFEGCRRYRIGNYRIVYQFDATTLIVLSIRHRKDVYR"
     gene            complement(23293..23808)
                     /locus_tag="PK063_06730"
     CDS             complement(23293..23808)
                     /locus_tag="PK063_06730"
                     /inference="COORDINATES: protein motif:HMM:NF014643.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system
                     prevent-host-death family antitoxin"
                     /protein_id="HMZ96777.1"
                     /translation="MVKTLPISEAREQLRALVEQANRTMARVIITRNGKPEAVLMGYA
                     EYESWLETLDVMADHDELAAIEAGLADVRAGRLVSAEDAYREAAPPKDTPLEGPGNIG
                     SGGLTEREVTVLHRIAAGSLENEIAHDLRLAPKTIHALKMSIFRKLGIRTHLEARHDT
                     VQKRKADKVGR"
     gene            complement(24312..25022)
                     /locus_tag="PK063_06735"
     CDS             complement(24312..25022)
                     /locus_tag="PK063_06735"
                     /inference="COORDINATES: protein motif:HMM:NF023273.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3365 domain-containing protein"
                     /protein_id="HMZ96778.1"
                     /translation="MSVAADNTESDLSETGRLLAILLDSGRVAIGRNQTLINDPSNAQ
                     TAFTPELFAAQATAIFKERTGHNLDDLPNANVPTLAKRLLERLMMESKKTVESYQPVL
                     NMKGLKYKGLIPATFGTETATRFQKWSGVYLKQTAPEHLVRNANNKPDSFEAEHMKEL
                     SEASSQRNKETVISKVDGGNSVRVLLPLFYEKNCLSCHGEPKGERDISGYSKEGGREG
                     ELGGAISVKIDMSKLAVR"
     gene            complement(25751..25993)
                     /locus_tag="PK063_06740"
     CDS             complement(25751..25993)
                     /locus_tag="PK063_06740"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96779.1"
                     /translation="MTQQQHIMVERVDELERMIVRLNGRIGELQRELQLTKGLTQGWS
                     GSSRLRTLLSGMKSHTTTTQPVRENRRVQRHDVCLL"
     gene            complement(26011..26562)
                     /gene="lexA"
                     /locus_tag="PK063_06745"
     CDS             complement(26011..26562)
                     /gene="lexA"
                     /locus_tag="PK063_06745"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HMZ96780.1"
                     /translation="MMTPKQFRNCREQLGLTQEQLAEALRMTRVSVARYESGMRRISG
                     AVEVAMTQLLNRSQVLMAGMVAAGVPIEPVAQSEWVDVPPSMVRAGETFALRVKGESM
                     IEDGILPGDLVVVRKQSTAHNGQTVVALVNGQATIKTYFKRERSIELHPANASMKPLL
                     VAPTDEFAIEGVLVGVIRHCDNA"
     gene            complement(26695..26767)
                     /locus_tag="PK063_06750"
     tRNA            complement(26695..26767)
                     /locus_tag="PK063_06750"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(26732..26734),aa:Gln,seq:ctg)
     gene            complement(26773..26913)
                     /locus_tag="PK063_06755"
     CDS             complement(26773..26913)
                     /locus_tag="PK063_06755"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96781.1"
                     /translation="MSGKLQQHSTPPDRTSQTPFERFTAALSKVVAVPKSALPTKKSR
                     KK"
     gene            27056..27838
                     /locus_tag="PK063_06760"
     CDS             27056..27838
                     /locus_tag="PK063_06760"
                     /inference="COORDINATES: protein motif:HMM:NF024098.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HMZ96782.1"
                     /translation="MAMLTVYCDDSGTDKNSRVAVVAGYLSNVAQWELFSKEWRKALD
                     EFGIDRMRRADLENFRGEFKKWNPERRIALLQRLQPIIKRRTKLPIASVVIKEDFERA
                     ISDDLKEKMGGVYGFLAYICLVSVGQWCGRSSRLHGDPIQWVFESGTEGSHQVSQMFD
                     VMYSDERLRNKSRLGGWSFQGKELAPLQSADLLAYECFKHIENQVVDRGRRPVRISWG
                     HLVGSERCPYMKFWEKPWLEKFSREFDQRLTPLNTNIPPHAQ"
     gene            complement(27887..28822)
                     /locus_tag="PK063_06765"
     CDS             complement(27887..28822)
                     /locus_tag="PK063_06765"
                     /inference="COORDINATES: protein motif:HMM:NF033547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
                     /protein_id="HMZ96783.1"
                     /translation="MNPTLPTTLQEAIQYFADPQRCQDLLSAMRWPQGPVCPNCRSHE
                     HGYVKSRGIYQCKMCRKQYSAKVGTIFEDSPIKLDKWFCALWMLTNAKNGVSSYEVAR
                     SLGVTQKTAWFMMHRIRLALQHGSIDRKLMGDVEVDETYIGGKARNMHHDKREKLMKN
                     EGSFRKAVVVGMLERKGEVRTAVLRTASEKLLGKSVREHVVPGSNLITDEAAGYTKVG
                     REYAHKVINHAETYVKGNVHTNSIENYWSLLKRGIKGTYISVEPFHLFRYLDEQAFRF
                     NTRKDNDQGRFMAALSQISGKRVQYRELIGQTTWH"
     gene            29355..30074
                     /gene="traT"
                     /locus_tag="PK063_06770"
     CDS             29355..30074
                     /gene="traT"
                     /locus_tag="PK063_06770"
                     /inference="COORDINATES: protein motif:HMM:NF017619.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="complement resistance protein TraT"
                     /protein_id="HMZ96784.1"
                     /translation="MAGGSLRGFLAVIVLTFGCSANVRDTDLLASNSLMLAPSTARTI
                     FLQNRNSSDNQDVSLHDLGARLGAKGYQVVQDPQAAAYVVLTNIVYCNQTKIELPVEE
                     MVAGGYGSGIGSSIISGLHGLTGMASMAGPQGALVGGAASLGLNAAEGIGNAMGSMFG
                     GPSRPNANENINYACIADLQITDLRATGGSLPVSQPGTPPPSGVYQTRLAANVHQKKL
                     DEQEATPLVQQRLSAAVAGHF"
     gene            30116..30835
                     /gene="traT"
                     /locus_tag="PK063_06775"
     CDS             30116..30835
                     /gene="traT"
                     /locus_tag="PK063_06775"
                     /inference="COORDINATES: protein motif:HMM:NF017619.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="complement resistance protein TraT"
                     /protein_id="HMZ96785.1"
                     /translation="MSRALSLFVGLLMLTGCSNVLRSGLVNDGSILLPPSAARTIYVQ
                     IRNTSENQTATPTDIPSRLRAKGYQVVADPMEAAYWLQTQVIYCHKAGEGVRPEAVAK
                     AGFGAGIGSGGTPLANAGGFDMEAMGGMFAGMPGGGLNAQAMRAMAMGGGGMPDMNAM
                     MRMAMNGRGGYPGMAPPPQSDDVIYLCVADVLVTEQAKNGPPRTYKMRSVAHVLQKHL
                     NIEEATPIVRDKFSASITGPF"
     gene            complement(30843..31937)
                     /locus_tag="PK063_06780"
     CDS             complement(30843..31937)
                     /locus_tag="PK063_06780"
                     /inference="COORDINATES: protein motif:HMM:NF012235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ96786.1"
                     /translation="MAAEITIHLVKTFPGRAPIRAQIRYPIEGSTVLILFGPSGSGKT
                     TILRSVAGLEWPEEGTIRFVSRVWLDTASGIRIPPQDRHIGYMSQDYALFPTYTVAGN
                     IAYGLNHLSSAERNKRVDEVMELFQLRGLEQAKPRELSGGQQQRVALARAVAPRPLLL
                     LLDEPLSALDAPTRLHLRDELRSLLKQLALPSIIVTHDWAEALTLGDVMAVISAGDVL
                     QVGAPIDVFSRPQNADVARVVGVETVVKGRVIEATGGMLRVSVNGTTLMALESESIGP
                     DVFACIRAEDVVLEQGRASGSSARNHLTGTVQSVTMLGASARVTLDCGFPLVATVTRS
                     TVEEFKLTQGLVITAAIKAGAVHLVSRQGD"
     gene            complement(31922..32596)
                     /gene="modB"
                     /locus_tag="PK063_06785"
     CDS             complement(31922..32596)
                     /gene="modB"
                     /locus_tag="PK063_06785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HMZ96787.1"
                     /translation="MNWIAIWVTCKLAGLTAVALLFVGLPIAYWLSFSRWRWKFLIES
                     VVALPLVLPPTVLGFYILIAIGPHSPFGRLYTELVGHPLPFTFEGLLLASILYSLPFA
                     VQPFAAAFDQVDRRLIEASWTLGVSKLQTFFRLIMPLSTAGLVTGAVLSFAHTMGEFG
                     VVLMIGGNLEGSTRTVSIDIYDEVQALNYAGAAKTALFLLVVSYAVLLVVYAVNRNVW
                     AAWPRK"
     gene            complement(32680..32883)
                     /locus_tag="PK063_06790"
     CDS             complement(32680..32883)
                     /locus_tag="PK063_06790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TOBE domain-containing protein"
                     /protein_id="HMZ96788.1"
                     /translation="MKLSARNQFQGNVVRINEGQAMAEVVVKVGTLEFVAAITEGSVK
                     NMGLKVNDQVTVAVKATEVMIGK"
     gene            complement(32897..33274)
                     /locus_tag="PK063_06795"
     CDS             complement(32897..33274)
                     /locus_tag="PK063_06795"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96789.1"
                     /translation="MVSHYQSKHWWLVLCGALFVTAGCSQAVLMEQESAQGGVVTYSY
                     KQDRGGPMGSPYRKQALDLMQAKCGGSSRLLREGEVRGYTSAGMGTIEGTEDEERGRR
                     WGIRFECKDREGGDKPAESLQHR"
     gene            complement(33252..34010)
                     /gene="modA"
                     /locus_tag="PK063_06800"
     CDS             complement(33252..34010)
                     /gene="modA"
                     /locus_tag="PK063_06800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009897 - external side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA];
                     GO_function: GO:0030973 - molybdate ion binding [Evidence
                     IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HMZ96790.1"
                     /translation="MRRFFAIILLILCAVSPVRAEELAVAAASDLNFAIKELIGEFEK
                     QTGHRVKVSLGSSGNFYAQLQQGAPFDLYFSADIGYPKKLEEGGLTVPGSLYRYAVGR
                     IVLWAPKSSPLDVNKGLTVLREPTIRKIAIANPKHAPYGRAAVAAMEHAQVYADVKDR
                     LVLGENISQAAQFIESGACDVGIIALSLALAPAMKSAGSYWEIPAEAHPPLEQGAVIL
                     KQSKNQELARSFLSFLQGPQGQEIMTRYGFTLPK"
     gene            complement(34225..35952)
                     /locus_tag="PK063_06805"
     CDS             complement(34225..35952)
                     /locus_tag="PK063_06805"
                     /inference="COORDINATES: protein motif:HMM:NF019042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
                     /protein_id="HMZ96791.1"
                     /translation="MRLREGLYIFRDQWSGHRVLLGIVVLLAACFFSAGVTEAADTGK
                     LVEKDGKYVFVESMDPSLKLLLERSVKSGMITQEEYEQVVKDSEERTQLLSPTFRGWY
                     DRGFNLSMNDNAFFLKIRFRSQLRYTQRFRNDAWRNPGEAKNFPELLGVFGDYRANRS
                     ENSASSFNVRRLRFYFMGHLFDPDFKYYIQMRAETAENAQSPGSLSLFDVNFTYTKLP
                     WANVQFGQYKVYFNRSQINSTASMQFAERALVQDAFTASGLDRRDIGITIMNDEELFP
                     VNYYFGVFNGAGPSFNRLGSFTSEEATVGCPGGQTSGNPFPSPAGCPANQRNLNANTR
                     IDVDRLMYVARLNWNILGRPGYGEGDLAYSETPQFAVGGGYSYNPAVNTSSDNAFVGL
                     DLANLNIRRQLAAFGNGRQLGLGIVDYSTWAADGVFKYRGFSLQGEFYFKNVIRHDKG
                     LPCMNAACTTTAPNNFGNAMGWYVQGGYYLIPRTVEVAARYAYWDPDTNSANDLIRQA
                     DLSLNWFLNGTYDHQIMVTYSNTQFGTGGYAIGRSAPLPPGSGTVPLDAVGGTLIENA
                     IRVQYQIFF"
     gene            complement(36016..36687)
                     /locus_tag="PK063_06810"
     CDS             complement(36016..36687)
                     /locus_tag="PK063_06810"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96792.1"
                     /translation="MNSRLIRSSRRGTSVLALMLIWALAAAGCARLPYTTKTIHEDQR
                     VVVAVQRDVQPQTYSHPVQLTSADLTSLLRGFSIREQQRVPLRWFAEEQPPKPLFRED
                     DLHALAPYLAEGFQHVGPNDRVHFEVRNPGFNPAYGRDTIAGWMAVRDPYLYLTIEYF
                     HTQIPVRKADDYDTNYPLTPPTPKEYIIYFEPGRFYASDEKRVPAVDFRQFLKSGEAG
                     ATAPR"
     gene            complement(36765..37604)
                     /locus_tag="PK063_06815"
     CDS             complement(36765..37604)
                     /locus_tag="PK063_06815"
                     /inference="COORDINATES: protein motif:HMM:NF024921.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HMZ96793.1"
                     /translation="MKGQWRMSHRVRAFLSTWCLAVVFWCGAGQAHAAESFVIAASPS
                     LKGLLERLGSGFEQAHPEVRVKLYFDSGLGLRQTIAGMENSMVGQYFVGSGPINLVAP
                     GGDEVITRLQVKYYVLPGTKRSYAVDQLVLVVPESLVEAPGSLEAIAQGNARLAIAER
                     TRTRLGAQTADMLRASGIEEAFKGRLDMATDGRGVIDHVLSGQADVGIIFGDQAVDQQ
                     QRLRVVGVINKGYQPTVHSMAMERYCPNRRLCEEFLTYIQSAEAQRLVRQAGYAVPAM
                     SGP"
     gene            complement(37660..38853)
                     /locus_tag="PK063_06820"
     CDS             complement(37660..38853)
                     /locus_tag="PK063_06820"
                     /inference="COORDINATES: protein motif:HMM:NF024138.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HMZ96794.1"
                     /translation="MSEKSKAEPSSNVVNSLRALRMAKGLSQGQLADGALITRQAVCA
                     IEADQYLPTTAVALRLASVLGCHVEDIFSLKTTGELIEGDWVWPGLAVSAVQPRTRVK
                     VAKVEERFVVRPVAALGEILNYTVPADGLIIGKAGSGPRSAKSDYRVLVRLLRERQIV
                     EREIAVAGCDPAINLASEYLHRHKDTSTVVGWSMGSAAALEALKRKEVHMAGLHILDA
                     KTGESNLPYLRRHLQGDDYIVVTFAAWEEGLLVRAGNPKRIRSVEDLIRPNVVVVNRE
                     EGAAARMLLDQRLEALGADGTSVKGYGVTVSSHFEVARHIAEGHGDVGIGVRSAAQIF
                     GLDFVPLQQARYDLVLPKRYLSSHPGLSHLLDAIASRQFRTEVEALGGYDMTETGKVR
                     SLRVG"
     gene            39191..40828
                     /locus_tag="PK063_06825"
     CDS             39191..40828
                     /locus_tag="PK063_06825"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96795.1"
                     /translation="MKRSAFALGVSLAVLWGSLTLPAQAVEEGQFIKKDGKWEYYSGE
                     DPGLKYLLLKGIITQDEYDRGLRVIEKREQVSKPNYTIDVNNGLNFRVGDKFFLKLRL
                     LTQVRYTHSAYNSAWGTVGDSRNPEILGGQVEYRAIRKQSDSNQFSVPRARLQFLGYA
                     FDPDFRYNISWAFDQTTWNQEGGSGRAGLLDAYVSSWHIPWLTVQAGQQRVWFNRATI
                     SSMATSTFADNLIVQNAFAANQQNARDVGVSISSDEDQYKFNYAFGIWGGVGANLARE
                     GTSVSQNVLPQTGTPGAPGAATTRTYNYDTRFMTGEMMYTARLLYKIAGNPGYGQGDI
                     LNSRTLQSAIAFGYAYNPAQNYLSSIRSDIVDRAYRQAVVKAYNGRLLAGGIWDFQTY
                     EADFIAKYQGWSFQAEGYYRHQRLRNANSGTSAFDLNTIPAAQFLGPAVNLGQAYGWY
                     AQVGKYIIPRKLELAVRYGFMDPSTQQVNDLVKEFGAAINYSFDGTYNNRLVIDYSNI
                     TMGSGGRAPDRFPFESQPGFGRDLVENRINVQYQFYF"
     gene            40868..41692
                     /gene="modA"
                     /locus_tag="PK063_06830"
     CDS             40868..41692
                     /gene="modA"
                     /locus_tag="PK063_06830"
                     /inference="COORDINATES: protein motif:HMM:NF024921.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009897 - external side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA];
                     GO_function: GO:0030973 - molybdate ion binding [Evidence
                     IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HMZ96796.1"
                     /translation="MRAAFRIRGLIAIVGFLISLGLTAQPALAQPETITIAAANSLKD
                     ALRKVLPLFEAEHRNINVRVIYGPSQTLRSQIEQGAPVDIFLPSLFEEIDQLEAKGLI
                     IQGTKRAFAATSLVLITGTALPAPISTIQDLQTIPIRHIAVGDPKTSSVGKVSAQFLK
                     YSKLEPKLKSQYVLGEHSRAVLDLVAKGEAEIGVVYRTDAISNPGVRILDTAPVGSHT
                     PVRYGVAAAWTAQNITAAGDFIEFLLSPTIQTQLQEFGFDRVSPEVGFAQREEVKP"
     gene            41689..42423
                     /locus_tag="PK063_06835"
     CDS             41689..42423
                     /locus_tag="PK063_06835"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96797.1"
                     /translation="MNGIGHPQQHSLSRHTNLILAFIGVMVAAGCAAPTPTPPKTVYQ
                     SGLNQVRIEKDPASTINAHPASLSATEVGTLLRGVRVWERRNALHRLFVGPADKIRAF
                     RDGEIAILAPALAKALSQASPSERVYYHLSHATEHGEEETSTGWLSIQDATLHLALRE
                     AHDRHGPGPDISKYDRQMPNVPERSPAFDATFEPEEYLVKVRSGGSLFAPDQQEELLI
                     RYREALAAMPAQPGLERESKPVPERH"
     gene            42448..42795
                     /locus_tag="PK063_06840"
     CDS             42448..42795
                     /locus_tag="PK063_06840"
                     /inference="COORDINATES: protein motif:HMM:NF021593.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HMZ96798.1"
                     /translation="MAILVVGGDSVSAITERAYAGGHGCVQHWSGRKTRDLMRSIPKD
                     TEAVVLVLDRVNHTLARKVRTEATRRGLPVFFQKRGRQVRAAGDRPLDVVHWLDTKDT
                     GLRKHRLDLKTPA"
     gene            43052..44077
                     /locus_tag="PK063_06845"
     CDS             43052..44077
                     /locus_tag="PK063_06845"
                     /inference="COORDINATES: protein motif:HMM:NF008106.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate ABC transporter substrate-binding
                     protein"
                     /protein_id="HMZ96799.1"
                     /translation="MMTFAHVASALAIVLALTTAALATESPSLLNVSYDPTRELYQEY
                     NAAFIKHWKEKTGNTISIKQSHGGSSKQARAVIDGLGADVVTLALAQDIDAISHQAGL
                     LPENWQTRLPHNSAPYTSTIIFLVRKGNPKGIKDWSDLVKPGLAVITPNPKTSGVARW
                     NYLAAWGYALKQAGGDETKAREFITRLYTNVPVLDSGARGATTTFVERGIGDVLINWE
                     NEILLGGQELGKDKFDIIVPPTSILAEPTVSLVDKVVDKKGTREVAQAYLEYLYSDVG
                     QNIAAKHYYRPQSATVAAQYAGQFPKLTLFTINEVSGSWSVTNKVHFVDGGLFDQVYQ
                     EISRTRK"
     gene            44154..44990
                     /gene="cysT"
                     /locus_tag="PK063_06850"
     CDS             44154..44990
                     /gene="cysT"
                     /locus_tag="PK063_06850"
                     /inference="COORDINATES: protein motif:HMM:TIGR02139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015419 - ABC-type sulfate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008272 - sulfate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate ABC transporter permease subunit CysT"
                     /protein_id="HMZ96800.1"
                     /translation="MSILLKQPTVLPGFGLTLGFTLFYLSLIVLIPLAGLFVKTSALT
                     WDQFWQAVSDPRTVASYQLTFGLSFVAALINAFFGVIIAWVLVRYAFPGRKFVDALVD
                     LPFALPTAVAGIALTAVFSVNGWLGQYLEPLGIKVAFTPLGVLVALTFIGLPFVVRTV
                     QPVLQDLEKEIEEAAASLGATRWKTISKVIFPEVFPALLTGFTSAFARALGEYGSVVF
                     ISGNMPMRTEITPLLIITKLEQYDYAGAAAIAVVMLVASFVLLLIINGLQWWSGRRQV
                     AL"
     gene            45008..45886
                     /gene="cysW"
                     /locus_tag="PK063_06855"
     CDS             45008..45886
                     /gene="cysW"
                     /locus_tag="PK063_06855"
                     /inference="COORDINATES: protein motif:HMM:TIGR02140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015419 - ABC-type sulfate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008272 - sulfate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate ABC transporter permease subunit CysW"
                     /protein_id="HMZ96801.1"
                     /translation="MTTGILGLDIRTPRIASTVAEPFLVRLALILVSLTFLALFLFVP
                     LAAILFEALKHGLGAYLASFQEPDAIAAIELTLLATAIALPLNVVFGIAAAWAIAKFE
                     FWGKQVLITLIDLPFSVSPVVAGLIYVLLFGLQGSLGPWLAAHDIKIIFAIPGIVLAT
                     IFVTFPFVARELVPHMQAQGKDEEEAALVLGATGWQTFWRVTLPSIKWSLLYGVILCN
                     ARAMGEFGAVSVVSGHIRGETNTMPLHVEILYNEYNYVAAFAVASLLALLSLVTLAAK
                     SLVEWTSSVEQKENRP"
     gene            45883..46950
                     /locus_tag="PK063_06860"
     CDS             45883..46950
                     /locus_tag="PK063_06860"
                     /inference="COORDINATES: protein motif:HMM:TIGR00968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015419 - ABC-type sulfate transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate ABC transporter ATP-binding protein"
                     /protein_id="HMZ96802.1"
                     /translation="MSIEVRNVTKTFQTFTALHEINLHVKTGELIALLGPSGCGKTTL
                     LRILAGLEGPTTGSILLNDQDVTDRHIGERGVGFVFQHYALFRHMTVFENIAFGLRVR
                     PRATRPPDAAIDAKVRELLKLVQLEWLGDRYPRQLSGGQRQRVALARALAVEPTVLLL
                     DEPFGALDAKVRKELRRWLRRLHNDLHVTSVFVTHDQDEALEVADRVVVMNKGRIEQV
                     GTPEEVYDQPANPFVYDFLGGVNLFHGRVHEGRVQVGELKLALREESEVPDGPAIGYV
                     RPHEIDLHRQPGEEGAIEALVGRVQPVGAVARLEMVRLDNGDVIEGEVSQEQWRSLAL
                     SKGERVFVRPKNLRVFPEVAE"
     gene            46955..48088
                     /locus_tag="PK063_06865"
     CDS             46955..48088
                     /locus_tag="PK063_06865"
                     /inference="COORDINATES: protein motif:HMM:NF025885.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ96803.1"
                     /translation="MRDPRLDPEADYDLPTADKPDSRVARPSKVLSASDPQAMVQSIR
                     ASCLVFEDSASQALLQRVRRIAPTETTALIIGETGTGKKLIARHVHELSTRRTGPFIA
                     VNCAAITESLMESELFGHERGAFTGASSTKAGWFETAQGGSLFLDEIGDLPLALQAKL
                     LRVIQQREVVRVGARRPLPVDVRLIAATNVKLEEAVAAGRFRADLYYRLHVVTLQLPP
                     LRERRDDILPLATHFLSLYGSRLGFTQARLSPEATDQLLQYPWPGNIRELENTIHHAL
                     VVCPGTEIRVSDLRLPSGQYDVHVTKPAAETALTGLEQALQSLFQADHPALHRRIEET
                     VFRTAYDFCDRNQVRTAQLLGISRNIVRDRLIRYGLLPSLARQ"
     gene            complement(48120..48290)
                     /locus_tag="PK063_06870"
     CDS             complement(48120..48290)
                     /locus_tag="PK063_06870"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96804.1"
                     /translation="MGVLIIGALSLTVLVWGLITSLANEADAEKRRLAQRRLREDGSD
                     DRAGASESLLAA"
     gene            complement(48396..48857)
                     /locus_tag="PK063_06875"
     CDS             complement(48396..48857)
                     /locus_tag="PK063_06875"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96805.1"
                     /translation="MSRLGDKARTYRLPTIINGALTYKTLELDRGRWVAVCFVPKLGV
                     IEADLLDRYATDVELLGATLVLVSMDAGRWPRDSFASLPHVRIPVVGDPLGRLQRLFG
                     GATARSWGRARTFLLDPDGHFRFHLMHSLSERGMGVFMELLRTYQDEEVPA"
     gene            complement(48912..49226)
                     /locus_tag="PK063_06880"
     CDS             complement(48912..49226)
                     /locus_tag="PK063_06880"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96806.1"
                     /translation="MSSHTRTDSAHQADSRLVDAWLLENLRWNGPQTLDYLSRLFPKL
                     EEARLLFAIDRLSRNGQVVISPPQNGDYLISVRSIGQEGLREDQHGSCRRAHERAPSA
                     VQ"
     gene            complement(49475..49840)
                     /locus_tag="PK063_06885"
     CDS             complement(49475..49840)
                     /locus_tag="PK063_06885"
                     /inference="COORDINATES: protein motif:HMM:NF021460.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2173 family protein"
                     /protein_id="HMZ96807.1"
                     /translation="MAKSLDELLTLKGVIASGEFAENGRLIAFRSHGAPLPDDVALLT
                     AQFSAAISQLLGVLAAAHSRLSGFNWIPQQGWAYSGGDLTIAVGGSRGVFVRTAEADF
                     NQLFEALIGSREPVGAEVR"
BASE COUNT        10731 a        15043 c        14327 g        10042 t
ORIGIN      
        1 aggtcatgcc ggaattggaa ggtgttgaac tgaaggatta cgccatgagt tggagtcagc
       61 catgaaactg gtcagtttcg aggttcacac cccggtcgga atctttcgca ggatcggcgc
      121 catgcgggca ggatcaattg tcgatctcaa catggcctat gcccgcctgc tcgcggagca
      181 acgggaatcg aggccgcggc gtctcgccga tgcgcaagtc ccggccacga tgctggagtt
      241 tctgcaaggc ggcgcctctg ccatggatgc ggcccggcgt gcgtttgatt tcgtggcaca
      301 ggatgcctcc ctcaagggcc catccggtga aacgatcatc tacaacgcgg ccgatgttca
      361 tatcatcgcg cctctgccca accccgcctc gctccgcgat ttcatcgcct tcgaagacca
      421 cattgccgcc acgtcgaaac ggcgaggcca accgattcct cccgaatggt acaaggcgcc
      481 cgtgtactac aagggtaacc accggaccat cgtgggcccg gattactcgc tcccctggcc
      541 gttaaacact cagaagctcg attacgaatt ggagctggcc tgcatcattg gacgcgacgg
      601 catcgatgtg ccggaacgcg acgcggcgca atacattgcc ggctacacga taatgaacga
      661 cttgagcgcg agagatatcc agttccagga aatggcctgc cggctcggtc ctgcgaaggg
      721 aaaagacttc gccaccgcca tcggcccttg catcgtgaca ccggacgaaa tcccggatct
      781 tgcttcgctg cagatgatcg cccgtgtcaa tggagaagtc tggtcgcagg gccgcttcgg
      841 ttcgattcat tggtcattcc ctcagatgat cgagcatgtc tcgcgggggg aggccatcta
      901 tcccggcgac cttttcggct cgggaacggt cggcggcggc tgcggccttg aactcgaccg
      961 gtacttacag ccgggagact gcattgaatt ggaaatccaa cctatcggca ttctgaaaac
     1021 gacgatcgcg ggacacaaca agcgctcgcg cgaggaggca tgatgccagt tgtcacgaaa
     1081 tcttcggaag ccgcgatcgt ggagaccgtt gaacgacagc gggcgatgta tgatggatcg
     1141 gacatcgacg tgaggatgca gcacctcatt cgcgacaccc cgcatcccac cttgtcgtcc
     1201 tgggatattc aacgcctgct gcgtgcctcg cgcgcggtgt atttcgacag ccatgtggag
     1261 gtcgtgtccg gtcaccatac cgaggtctac ctgcgattcg aatccatcgg ccgttttccc
     1321 gacctcgtga cgatcatcgc gtccaacatg gctgagtgga ttcttcaaac atttcaccat
     1381 gacccgccag ccggaattct taccacgtcg tctgacgcgc ggctgttggc gaaacgaacc
     1441 tgcgagatcc tggcgacgca tcttccctta cgcaccgtgc tgacgccttt taaccccgac
     1501 acgggcaaga tcggcacgga gatcatcagc ggaacggtgg cccccgggga gcggttcctt
     1561 tcactcaacg atgtcaccac acgcggcatg tgcgtcagca agttgggaaa ggtcgtcacc
     1621 gatcacggcg ggcagcttgc gggcatgatg gtgtttgcga ggcgggacag cggacagttt
     1681 ccgttcatgg atgagctgac ggccacctat ccgttttact tcggcgtgga tctggacatg
     1741 ccgcagtggg aaccggccga ctgccacgcc tgccgggacg ggaaaccgtt ggtgtcctgg
     1801 agggacctgc ccgcgctctg acgtgatgcg gatagccgat cgatgaagga ggcagctatg
     1861 gaccaggccg gcgtcgcaca ggacatcaaa cgcagcgacc tccttgagat gtacttctac
     1921 ctgcggctca ccagaagcct ggaggaccgg atcacggccc tctatcggca aggccggatc
     1981 gtcggtggcg tctacaccag ccacggcatg gaagccatcg ccgtcggcta tgcgtccgcc
     2041 ttacagtccg acgatgtcat cgcccccttc catcgcgata tgggagcgtt cctgattcgc
     2101 gggttttccc ccggagaaat tatcgcccaa tacctcggca aacaggccgg gcccacaaaa
     2161 ggcaaagacg gcaacgtgca catgggcgat ctgaaacgcg gagtgatcgg cttcgtcagc
     2221 cacctggccg acaacatgcc ggtcgcggcc ggcgcggcac tggcgttcaa aatccgtggt
     2281 gaatcccgcg tggccttcgc aggaaccggc gacggtggca cgagccgtgg cgacttccat
     2341 gaagccatga acttcgcagc ggtgcgcaaa ctgccggtcg tcttcttctg caccaacaat
     2401 cagtatgcct actccacgcc ggtccgttac caaatggcga tcaccgatgt ggtggaacga
     2461 gccaaggcgt atggtatgcc gggcgaaatc gttgacggca acgacgtggc cgccgtctac
     2521 ctggcgtccc gtcgagccat tgcgaaggcg cggtccggcg aaggtccgac atttctcgaa
     2581 ttcaaaacca tgcgcatgca cggccattcc gaacatgacg cggccacgta cgtcccgcgt
     2641 acgctgctgg aagattggaa gaccaaagac ccaattctgc gtgccgagca gttgctcatg
     2701 cagctgggct acggggatga ctcctacttt catgaggtcg gggaacgcgc caagaaagac
     2761 gttgatgcag gcaccgagtt cgccgagcaa agcccgctgc cggaaggacg tgagacgctt
     2821 gtcggcgtgt tcgccaccca agacgaggtg ttgccatgac gaccgcgacc gtcacgcagg
     2881 agatccagac cacctacgtc gatgccatat cacaggccct ggacgaagaa atgagccgcg
     2941 acgaacgggt gtttctcatg ggtgaggaca tcggcgcgta cggcggcgca ttcaaagtca
     3001 cggaagggtt tctcaagaaa tatggcgaat ggcgagtctt ggatacaccc ctctccgagt
     3061 ccggcttcgt aggcgccgcc atcggcgccg ccatgatggg attgcgcccc gtggtcgaaa
     3121 tgcagttcgc cgacttcatt tcctgcgcct tcgatcagat caccgaagtg gccgccaaaa
     3181 atcactaccg ctggggagcg gcagtccctc tagtgatccg ggcgccattc ggcgggggcg
     3241 tccatggagg tccgtttcat tctgaatgtc cggaaggctg gttctttcat tcgcccggcc
     3301 tcaaaatcgt tgcgccctcg acgccctatg acgccaaagg tctcttgata gccgccatcc
     3361 gcgatccgaa cccggtcctc tacttcgaac ataagttttt gtatcgacgg atcaaggcga
     3421 cgctgccgca ggaagagtac atcattcctc tcggcaaggc tgacgtgaaa cggtccggcc
     3481 gcgacatgtc gctgattact tatggagcga tggtgcattt ggccttggag gcggcggaag
     3541 tgctgcagca agaaggaatc gagctggaag tggtggatct tcgcacgctc attcctctcg
     3601 acaaagagac gctctacgcc tccgttcgca aaaccagcaa ggcgatcatt ctccatgaag
     3661 acaacaagac cggcggcatc ggggccgaaa tttccgcgct gctgaccgaa gactgtttcg
     3721 actgtctgga cgggccgatt cttcgcatcg ccccgcctga cacgccggtg ccgttcagca
     3781 caccattgga agaattcttt ttgcccaagg tcagcgacat cgtcgcggga gccaggaaac
     3841 tcgcggccta ttgatgggat ggactaggta aacaggcatg caggagacgt gatccgtggc
     3901 taccgacatc gtcatgccgc agctcggtga aagcatcgct gaaggtaccg tcgtgaagtg
     3961 gctgatccaa gccggcggtg cagtcgaaaa agaccaaccc ctcctggagg tggaaaccga
     4021 aaaggtggcg ctcgatgtgc cgtctccggc cgcggggttc ctcgcggagg tgatggttca
     4081 agagggcacg acggtgccgg tgggcacctt actcgccagg ctcgagactc aaccggctgc
     4141 agcgggggtc gtcaaccggg tcggagacgt gggtgtgcgc gcaagacagg agcaacagcc
     4201 gggcgaacag cactattcgc cggctgtcaa acagctggca cgagagcatg gggtggacct
     4261 gaccgttgtc cccggcacag gggaaggcgg ccgggtgacc aagaaagacc tgctggatta
     4321 tgtctccacg cgtcaacagc caagtggcga gccaccacga acggctcagg ctccaaccgt
     4381 cgtcccgcag ccccgcgaaa cgccggagga aatcattccg ttcacccaaa tgcgaaagac
     4441 cattgccgac cgcatgctcc tgagccggcg cacctccgcc catgtcacca cctttttcga
     4501 agcggacttc cggggcatcg acatattccg cacgggacgc acactcacct acctgccctt
     4561 cgtcatcagc gccgtcactc gggccatgaa agacctgccg ttgctgaatg cctcctggcg
     4621 tgaccaaggc ctcgcgatca aaaaagctgt ccacatcggc attgctgtcg cgctcgacga
     4681 aggcctgctg gtgccggtga ttcgccatgc cgatcagaaa ggactcaccc agttggcgca
     4741 cgaagtcgcc gagttggcgg aacgggccag gaacaaacgg ctgacgccgg atgacgtgct
     4801 cgacggcacg tttacgatca ccaatcacgg cggattcggc agcctgttca gtacgccgat
     4861 cattcatcag ccacagacgg cgattctcgg cgtgggatcg gtccaaaaac gcgccgtggt
     4921 gatcgacgac gccatcgcca tccgccccat gtgttatctg agtctctcct tcgaccatcg
     4981 catcatcgac ggggcgacgg cggatcgatt catggccaag gtgaaacagc atctccaaca
     5041 gagcgattgg gagaaacttc tgtgaccgcc agacaccatg ccgtcatcgt cagcgcggtt
     5101 cgaacgccga tgggaagctt caacggcggg ttcagctcga tcccctcaac taaattggga
     5161 agtattgcca tcgccgaggc gctgcaacgc attcagctga cgggcgaaca gatcgacgag
     5221 gtgctgatgg gatgcgtgct cagcgccggg ctcggacagg cacccgccag gcaagcggcg
     5281 atcggagcag gactgccgca ccgggtcggg gctgtgaccg tgaacaaggt ctgcgggtcc
     5341 agcttgcaga cagtcatcat ggcagccagg gccattgcct tgggtgaagc gcaaatcatc
     5401 attgcaggcg gaatggaaaa catgacccgg gccccctttc tgctggagaa agccagacag
     5461 ggctatcggc ttggacatgg agagctgacg gacagcctga tcaaggacgg gctctgggat
     5521 gtgtacaacc aatttcacat gggcaacgcc ggagaactct gcgccgccag atatcagttt
     5581 tcacggcagc aggtcgacga ctttgccatg gaaagttaca gccgcgcgcg tgaagccatc
     5641 accgccggtt cattcaccag ggagattgtt ccggtcgagg tgccccagaa aaaaggcgca
     5701 ccactcatga tcgcagacga tgaggaaccg aaccgggtcg atctctcaag gctgcgacag
     5761 ttgaaacctg tctttcagga cgacggagtg ctgacggtgg gtaactcccc gtcctgcaat
     5821 gacggggcgg cagcattagt cgtcatggcg gaggaagagg cccaccggct tggattgccc
     5881 cccatggctc gcatcgtggg atatgccgga gctgcgctcg cgccggaatg gttcaccatt
     5941 gcgcccatcg acgcgattcg gcggctcttg aaacagacgg agttgacggt cagcgacatc
     6001 gacctctttg aaatcaacga agccttttcg gcggtctcct tggcgatcac gcgtgaactc
     6061 ggattggatg ccaagaaggt caacgtcaac ggcggcgcgg tcgcgctggg tcatcccatc
     6121 ggcgccaccg gcgcacggat cctgaccacg ctgctctatg cgatggagga acgggatgcc
     6181 catcgcggaa tcgcgagcct ctgcattggc ggcggtgagg cactcgcact gctcgtggaa
     6241 cggccgagaa aaatacagca tcagtgatca cacgtgcgca agagcagcag ccatggaatc
     6301 gcgaatgacc atcgatgaca tcaccacagt cggcgtcgtc ggcgcggggc aaatgggacg
     6361 cggcatcacc caggtgttgg cgacggctgg ctggaaagtg ttgctggtgg atgtgacgga
     6421 agaggcgctc gaggacgcga ccaaaaagat ctggcagggt gtcacgaagg cggtggaaaa
     6481 aggcgcgctc cgaggtgatc aggccggatc ggccatggcc atcatccatc cgatacggca
     6541 catgcaacgc ctgcgtgagg cgcaggtggt gatcgaagcg ataccggaag atccggtgat
     6601 gaaacgggcc ctcttcgcgc aattgggaca gatctgcgag ccctcgaccc tgttggcgag
     6661 caatacctct tcaatttcga tcgccagcct cggcatggtg tcagggcggc ccgaccgggt
     6721 cgttggcatc catttcatga accctgtgcc ggtgatgcga ttggtggaag tcgtccgcgc
     6781 cattggcacg tcggaacaga cgatgcgcct ggcgcttgaa ctcgttcaac gcgcagggaa
     6841 gacagccgtc gtctgcaagg attttcccgg cttcatcgtc aatcgggtgc tcattcccat
     6901 gatcaacgaa gccatttttg cgctggagga tggggtcgcg acggcggaag ccatcgatct
     6961 ggcgatggtg gaagggacca accatcctgt cggtcctttg gcactggcag atcggatcgg
     7021 cctggatact gtactcgcca tctgcgaggt gctccatcag gacttgggtg atccgaaatt
     7081 ccgcccctgc ccgctgttgc ggaaatacgt agaagccggc tggcttggca ggaaaagcgg
     7141 acatggattt tatcagtacg gagatcagcc ggtaatgcac ctgacctgac gtttcctgtc
     7201 cgtgattgga ggaacgcgtc atgaacgagc ggaaatcccg attcacgtcc ctgtccggct
     7261 tggagatcga gcggtgttac ggtcccgatg atctcaaggg ctggagcgcc gagaaggatc
     7321 tcgggcaacc tggggccttc ccttacaccc gcggctgtta tcccaacatg tatcgcagcc
     7381 ggctctggac catgcggcaa tttgccgggt tcggctcagc ggacgacacc aacacacgct
     7441 tcaagtatct gctggatcac ggccaaaccg gcctgagcgt ggccttcgac ctgccgaccc
     7501 tcatgggtct cgactctgat gatccgctcg cccgcggcga agtcggatat tgcggggtcg
     7561 ccatttcctc cctcgctgac atggagcgac tgttcgacgg cattccgctc gaccaggtca
     7621 ctacctccat gacgatcaac ggacccgccg ccgtcctctt cgccatgtat ctggccgtgg
     7681 cagaaaaacg cgggatcccg ttcgagcgac tgggcggcac gattcagaac gacattctga
     7741 aggagtacat cgcccagaaa gaatggctgt ttccgccgga accgcatctg accttgatcg
     7801 tcgacaccat cgcgtattgt gcggctcatg tcccgaagtg gcatccaatc agcatcagcg
     7861 ggtatcacat ccgggaagca ggctcgacag cgatccaaga actcgccttc acgctctata
     7921 acgggctgac gtacgtcgag gcggccgtga aggccggtct cgaggtggat tcgtttgcac
     7981 cgcagctctc ctttttcttc aacgtccata atgatttctt cgaagagatt gccaaattcc
     8041 gcgcagcccg gcgcctctgg gcccgcgaga tggaacggcg gtaccatcca aagaaccccc
     8101 gttcactcca actccgctgt catgcccaaa ccgcagggtg ctccctcacc gcccaacagc
     8161 cgatgaacaa cgtggtgcgg accacgctgc aggccctcgc cgccgtgctc ggcggcacac
     8221 aatcacttca cacgaattcc atggatgaaa cgctggcgct gccgacggaa gaagccgtga
     8281 aactggcgtt acgcacgcaa cagatcattg cggccgagag cgagacggtc aattcggtcg
     8341 atccattggg cggatcatat gttgtcgagt cgctaacgaa ccgcctggag gaaggagcgc
     8401 tggacctctt tcgcaaactg gacggactgg gcggcatggt ctccgccatc gagcgcgggt
     8461 ttccacagcg ggagattctc gatgcctcgc agcgatatca gcgtgagatc gagcggcagg
     8521 aacggagcat cgtcggggtg acgacgcata gagaagaaga cgttcgatcc attcccatcc
     8581 tgaagatcgg cccggaagtc gaacaggaac aggtggcccg actgtccgat ctcagaaaat
     8641 cacgcgaccc cttcaagatg gccggctcgc tggaagagct gcaggaaatg gccgcctgtc
     8701 accagaacct catgccctca ttgatcgaag ccgtgaaggc gaaggcgacg ttgggtgaga
     8761 tttgtgccgc cttgaaggaa gtgtatggaa cctatcggga accggtggtc ttatgaaact
     8821 cggcgccttt gacatctacc cggtaaccga cggccgattc cggctggacg gcggcgccat
     8881 gttcggggtt gtcccgaaag tgctgtggca aacctgttgc ccggcggatg acctgaaccg
     8941 cattccgctc agcctgacct gcctgctgat ccgggcccac ggcaagcata tgctggtgga
     9001 tacggggctc ggcgataagg agaatgagaa attccgctcg atgtttgcgg tcgaacgaaa
     9061 gcccactctc cgagagtccc tctcgcaaca tggcctctgc cgcgatgata tccatctggt
     9121 ggtgaatacg catctgcact tcgaccacgc gggaggcaat acggcaaccg atggacgcag
     9181 cgcagtggcg ccgacgtttc ccaaggccac ctattatgtc cagcagacag aatacgacga
     9241 tgcgatgcag gccaacgaac ggaccagggc cagttatcgc cgggacaatt tcacgccggt
     9301 ggcggaggcc aaccagtggg ctttgctcaa gggtgagacg gaactcctgc caggagtgac
     9361 ggccattgtc acacccgggc atacgcgcgg ccatcaaagt gtcaaagtgg aatccgaagg
     9421 ccgggtcgcg tttttcctcg gcgatctcat tcccaccgtg tcccatcttc cgcttcccta
     9481 catcatgggg tacgacctcg accctgttca gacgctcgac agcaaacgat gggtgctgga
     9541 gcgtgcctgc gaggaacatt ggttgttgct cttcgagcac gatccgtacg tgcaggccgg
     9601 atacgtcagc aaaaccgtgg acgggaaata tgctctccag gaggtgacgc tatgaccgtc
     9661 gcggcaacac ccttgcgcat tctgatcggc aaggtgggat tggacggcca tgaccggggt
     9721 gtaaagctcg tcgcccgcgc gcttcgtgat gcgggcatcg agatcattta cacagggctt
     9781 caccagagcc ctgaacagat cgtgacgacc gcaattcagg aagatgtgca ggccatcggt
     9841 ctcagcatcc attccggcgc acataattcc ttgttccccc gcatactcgg actgctgcgg
     9901 gaacgaggcg cggaagacat cgtggtcttc ggtggaggca tcatacccga cgaggatgtg
     9961 ccgcgattga aggcggctgg cgtgcagatg ttgttcaggc ccgccacacc gatgcaggac
    10021 atcgtggaat ttgtgaacgg gcttcgaacc gaacgctgag aggattcgag ccatgcgtgt
    10081 gttggacacg tccatacgac gagactcgga cgagtttcgc cggaaccagg cccattacga
    10141 aggcttgatg gccgatctgc agaagcatct ggagatggtg tgggccggcg gatccaggga
    10201 ggcgatcgcg ctccacaagc agcgcggcaa actcaccgcc cgcgaacgga tttcatcact
    10261 cctcgatccg ggttctccct ggctggaact gagtcccctt gccgcgttcg gcctctatga
    10321 caatcaggtg ccgtcagccg gactcattac cggcatcggt tcggtgtccg gccggttctg
    10381 tgtcatcgca gcgaacgatg cgaccgtcaa aggcggcacc tacttcccga tgacgatcac
    10441 caaacatctt cgcgcgcaaa ccatcgcgtt ggagaaccgg ctgcccgcca tctacctggt
    10501 agattccggc ggcgtattcc tcccgatgca ggccgaggtc tttgccgaca aggaacattt
    10561 cggccggatc ttcttcaatc aggcgcgcat gtccgcggcg ggtcttcctc aaatcgccgt
    10621 ggtcatgggc atgtgcacgg ccggcggcgc ttacgttccg gcgatgtgtg atgagaatgt
    10681 catcgtccag gggaccggca ccatttattt ggccggccca ccactggtca aggcggcaac
    10741 cggcgaggag gtcaccgccg aggcattggg cggggctgat ctgcacacac gactctccgg
    10801 tgtgagcgac catttggccg atgacgatcg tgacgcgttg gacatctgtc gttccatcat
    10861 cgccacattg ccccggcgac tccccaagcc gcgccggaac cacatcgacg agccgctgta
    10921 tccagcagag gatctctatg gactcatccc cgccaacccg cggcaaaagt gggacgtccg
    10981 tgaggtgatt gcccggctcg tggacggcag ccgcttccac gaattcaagg cgcgatatgg
    11041 cgctacgctt gtctgcggct ttgcgcagtg gatgggccat atggtgggga tcgttgccaa
    11101 caacggcgtg ctgctgtccg aatcggcgtt gaaaggcgcg catttcgtcc agctttgcgc
    11161 ccagcgtcgc gtgccgctcg tgttcttgca aaacatcacc ggcttcatgg tcggaaagga
    11221 ctatgagagc cggggcatca tcaaagacgg ggccaagatg gtccaggcgg tgtcgactgc
    11281 ggaagtgccc aagttcacga tcctgatcgg cgcctcccat ggggccggca actacgcgat
    11341 gtgcgggcga gcgtacggcc cgagatttct gttctcctgg cccaacgcgc gcatctcggt
    11401 gatgggcgcg caacaggcag cccaagtgct cgtcacggtg aaggaacaac aacgagcgcg
    11461 agagaaggcc gctttaacgg atgacgaacg acgccgcatc atcgaggcca cccagcggca
    11521 atatgaacag gaaggcagcc cttacttcag cagcgcccgc ttgtgggatg acggcatttt
    11581 ggatccaacc gacacgcgcc gcgtgatggg actctgcctg gatctcgccg cattggcgcc
    11641 cgtgaaggac agccatgcgc cggtgtttcg tatgtgagca gccagaggag gtgcgaatgc
    11701 ggccattcac cacgctcatg attgaatcga atggcgccat tgcgcgtgtg acgctcaatc
    11761 gacccgaccg tcggaatgcc ttcgacggcc agatggcgac ggaacttcgg gaagcctttg
    11821 aagacctggc gcacgatccg tcgatcagag ggatcgtgct ggccgctgcc ggctccgtct
    11881 tttgtgcagg agccgacctt caatggatgc agtccgacgg gccggcgtcg gaaactccgg
    11941 cgatgcggga cgcccatcac ctgctgcgca tgtttcgcgc catcgatgag tttccttgtc
    12001 cggtcatcgc ccgggtgcag ggatcggcat tcggaggcgg acttggtctc ttggccgtct
    12061 gcgacatcgt cgtggcgacc gaggaggcca cctttgcctt gagcgaaccc cggcttgggt
    12121 tgattccggc cgtcgtcgcg ccgtttctct tacacaaagc gggcgaatcg tttctccgac
    12181 ggtacggcct caccggcgaa acgttctgcg catcgacggc ccagcgatac aacctggccc
    12241 atgacgtcgt cccacagagc aatctggatg accgtatcaa tgaattgagc gacgcgctca
    12301 tgcagctggc gccctgtgcc accaaggaaa gtaaactgtt gtttcaccgg ctgcgggccc
    12361 tatccgataa agaacgcctg gccctggggc cggaatacaa tgcccgcgcc cgttgtgctc
    12421 cggaagcagc cgaagggctg cgcgccttta tcgaaaaacg gccgcctgcg tgggcccagc
    12481 cacgtgagcg gaagccgcag gaggcgacga cgtcggacga tgttgtgctt cgccacagat
    12541 gagactcgcc ggttgcctgt ccggatcatt gaggtctcac ctcgtgacgg actgcaacac
    12601 gaagcgatct tcgtgccgac ggcgcggaag atcgacctga tcaatgccct gtcacacagc
    12661 ggtgtgacag aaatcgaagc cggttccttt gtttcgccga ccgccattcc gcaactggcc
    12721 gactccgatg aagtgttccg cgctatcgac cggcttccgg atgtgaccta ttccgccctg
    12781 gtgccgaacg aacggggcct ggaacgggca cgggcggccg cagtgcagaa gatcgccgtc
    12841 ttcacggccg cctcgaacag tttcacgcgc cataacatca aggcaactgt ccaggaatcc
    12901 ctggttcgct ttacccccgt gatccatgga gcgaaacggg acgggatgtt ggtgcgaggc
    12961 tatatctcca ccgccctgtg gtgcccctat gaggggcgca tagcgcccaa actgactgtg
    13021 gacgtcatgc ggcggttgct cgatctcggt gtggatgaca tctctctggg agacactatc
    13081 ggcagagcgt cgccggcaga tatccgcggc ttgctggatg ccgtcatgcc gcatatcgaa
    13141 ccgactcgcc tgtcgctcca tgtccatgac acctacggaa tggccgtggc caatgtgctg
    13201 acggcctggg aagactatgc gatcacggcg ttcgattgtt cagccggcgg tctgggcggt
    13261 tgtccctatg cgcccggtgc gtccggcaac gtcgcgacgg aagatgtggt gtttgccctg
    13321 aaggcctccg gggcgacggt cgcggtcgac gaagaactga tcgtcgactg tgcgcgtcag
    13381 ttgagcgcag tgatcggaca tcccctccac tcgcggctgt cacagatatc gcggccccgt
    13441 atcgggcaac cggccctgaa ggtgtgatgt gaaccacgtc actgcgcatc catccttctt
    13501 ccgacacgat gccgccgagc tggcgagaca ggtcgaagcc ggggaggttc gagccgtggc
    13561 gcgtgtcatc agtttgctgg aaaaccggga tccgctcgga gcggcggtgc tgactcatgt
    13621 ggctccgtct ctgaatcgcg ccttggtgat tgggatcacc gggtatcccg gcaccggaaa
    13681 aagtacggtg atcgatcagc tcatcaccgc ctaccgccga ctgggagaga aggtcggcgt
    13741 gctggcggtg gatatcagca gccccgtcac aggcggcgcg gtcctcggcg atcgcatcag
    13801 aatgcagcgc catacggatg atgcccgggt ctacatccgc agcatggcga cacgcgggca
    13861 ccagggcggg ctcgccgccg ccacgcggca ggcagtacgg gtcttggacg ccgccggctt
    13921 tggcgtgatt ctgatcgaga cggtgggcgt cggccaaagc gacgtcgaca tcatgcaggt
    13981 cgcccatacg gtggtcgcag tagtcgcgcc ggggctcggc gacgatgttc aggccatgaa
    14041 ggcgggactg ttggaggtcg cggacatcgt cgtggtgaac aagggcgatc gcgaaggggc
    14101 ggatgcagcc ctgcgggatt tacgtgaatg gtgcaaaacg gtgattcgcg ccgtggcggt
    14161 gaagggggaa gggatcgcgg aactgattgc ggtcatcgcc gaacacgaac ggtggcgaga
    14221 tctggacagg ccggcactcc ataatcggag agggccctcc atcgacctcg gctcgcgaac
    14281 gggataacgc tgctgctgtc attgccatga ggtggtgcat gctggccgat cgactggctc
    14341 actatacgca atcgctccgg ttcaaggatc tacccggcga cgtggtccat gaggtcaagc
    14401 gccgcattct ggacagtctg ggctgcgcat tcggtgcatg gactgccacc ccctgccgga
    14461 tcgcgcggga gatggcgctc gcagtgaagg tccccggcgg ggcgacggtg tggggaacga
    14521 atcacaagac ccttcccgac ctcgcgacct tcgccaatgg cgccatggtc cgctacctcg
    14581 acttcaacga tacctatctg tccaaagaac cggcgcatcc ctcagacaat atcgcggcag
    14641 tcctagctgc gggggaaaca gcgcatgcct ccggccagct catcattcag gcgctcaccc
    14701 tgtcctatga aatccaatgt cggctctgcg acgcagcggc cttgcggcca cgaggctggg
    14761 accatgtcac ttatggcccc ctctcgtccg cactcggcat tgccaacgtc ctcaagctga
    14821 cggacgcgca gacccgccag gccgtcaacc tggccggcgt ggccaatgtc gctctgcgcc
    14881 agacacgggt cggcgatctg tcgatgtgga aagcctgcgc attctccaac gccgcacgca
    14941 acggcatgtt cgccgccctg ctcgcccggc gcggcatgac cggccccgcc cccattttcg
    15001 aaggcgagaa agggttcatg aagctggtct ccggcccatt cgaactgccg atgttgggcg
    15061 gggaagcgat gccgggcgga gagccggtgc ccttcaaaat tctgaagacc tgcatcaaac
    15121 acttccccgt ggaataccac gcacaaagcg ccgtcgaagc cgcattggcg ttgcgagcgg
    15181 agctgctggc gacagaagga aagacctgga tcaataaggt agccgatgtc gagatcggca
    15241 gctacgacgt cgccatcgaa attatcggac gcgatccgga aaagtggcag cccgcgacgc
    15301 gggaaacggc cgaccacagc tttccgtact gcgtggcggt cgctcttgtc gacggccgcg
    15361 tgagtatgaa ctcgttcagc ccgaaacggc tgcgagaccc gcgtctccat gagctgatga
    15421 agaaaatcca cgtcgtgaaa ctggcggaac tcgaacatcg ctacccgact accatgccga
    15481 ctcgcctcac gatcagaacg tcacaaggct cgacgcatag ccgtcaggtg gatcaaccac
    15541 tcgggcatcc aggccatcct ctgtcggatc aggaagtggg ggacaaactc cggcggctca
    15601 cgtccaggcg cattgatcgc gcgcaactgg atcgcttgct cgccttcgtc tggcacctcg
    15661 aggaccagac agatatcgcc gctttcatgc cgctgttgag ggtgcgatca tgacgttcga
    15721 tcactcgagc ggcgacaaag gacggcgatt gcaagagata gtggccaggc gcacagtggc
    15781 catcccggga gcgtccaatg cattgaccgc cgttcagatt gaacgagcgg gatttgacgc
    15841 ggtctacgta tccggcgccg ccgtgtctgc tgcgcgcggc ctgccggaca tcggcctgat
    15901 ttccttgtcg gaaatggttg gcgaagcagg aatcatagcc agagccgtag ccattccaac
    15961 cattgtcgat gccgacaccg ggtatgggcc tccttcgacc gtgatgaatg cagtccgtga
    16021 attcgagcgc gccggcatcg ccggcatgca gatcgaagat caggaggcga caaaaaaatg
    16081 cggccatctc gagggcaaac gcctcattcc cctcggcgac atggtcgcca aaattagcgc
    16141 cgctgtgaag gccaggcaca atcggaactt tctgatcgtg gcgcgcaccg atgcgcggac
    16201 cgtcgatgga ctcgatggcg cgatccaacg ggccaaggcc tatgccgagg ccggcgcaga
    16261 tatgttgttc ccggaagcgc tgctatcacc ggaggagttt ggaacctttt cgctggcgat
    16321 acgaaacgcg ggcattcatc tcccgctgat tgcgaacatg acggagttcg gccgaacgcc
    16381 ctatctcagc gtggacgagt tccaagccct gggctatcag gcagtgctgt ttcccgtcag
    16441 ctcgttacgg gtcgcggcgc gcgcggtcga aaaactccta tcggagctga agttctttgg
    16501 ctcccagcgg aattggctcg accacatgat gaccaggcag gaactgtacg acctgattca
    16561 ctacgaggat ggcaccacat ccatgcggag gtcacatgaa ccagaccatg caggaacagt
    16621 caacggtgaa ggctcacgac catcctgaat acagcccggg cctggagggc gtgattgccg
    16681 gggaatcggc gatctgtcag gtcgatgaag gagaagcggg gctgcggtat cgcgggtatg
    16741 ccatcggcga cctcgccgga cgaagcagct tcgaggaggt cgcctacctg ctgctcttcg
    16801 gccacctccc tgccacaacg gaattggagg aattctctcg cctcctggtt cgcaatcgtc
    16861 ggcttcctca gcaggtgcac cacttcgtgg agagtctcac gcccgacatg catccgatgg
    16921 atgtgttgcg aaccgggatt tcactgctcg ggctgcatga tcctgatgcg caagacggat
    16981 cccgcgaggc gaaccttcgc aaatcggtgc gattgctcgc gcagatccct cacctggtcg
    17041 ccgacagcta ccagatcatg gcggaccggc aacccgccac gccggtttct cacggaagct
    17101 ttgccgaaaa ccttctgagt ctggttgcag ggcgccgata tggggaaatc ggggccgcca
    17161 tggcagaggc gctgaacgtc tcgctgattc tgtatgcgga acatgagttc aatgcctcca
    17221 cctttgccgc ccgggtcacc gcgtccacac tcaccgacct gcatggcgcc atcacggcgg
    17281 cagtggctac gctgaaaggt ccactccatg gaggcgccaa tgaagcggtg gccgcgatgt
    17341 tgatcgagat cggccggccg gagcatgtcg agttctggct gcgagaccag ctggcgcaca
    17401 agcgccgcgt gatgggattc ggccaccgcg tgctccggca aggcgatgcg cggtcggcca
    17461 tcatccaaca ccacgccgag cgattgagcg atctctgcgg cgatcgcaac tggtaccaca
    17521 tcgccaccac cctcgatcga ctcatgctgg aggaaaaggg actgcgcccg aatctcgatt
    17581 tttatacagc cgtggcctat ctcctcatgg gcatccctcg cggactatcc acgccgctgt
    17641 ttgtctgttc acggatcact ggctggtgcg cacatgtcat cgagcagcag gagcacaacc
    17701 ggttgatgag accacgggcg ctctacacgg ggcccgcgcc gaaagcctat gaacctcttg
    17761 aacgacgtac gtgaccatat cgagcaggct cgcgacgtat ctggacgcgc aacggatgtg
    17821 ccttgggcgt cgttcgcgga attccttcgt tcccgcgtct acgacccgca gctcgccaca
    17881 acgcatgcac tgacgttctg tgacgacgat cgtgctctgc gccgaaccta cacctatgcc
    17941 gaactgggag cgatcatcga acggctggcc ggagtcttcc ataccagatt cggcctgacc
    18001 cgtggagacc gggtcgccac gttgctcttc aaccacgatg tgacggtgct cacctacctc
    18061 gcagcctgga cgctgggagt cgcagtcgtc ccgatcaaca tcgaagaaac gccggagaaa
    18121 aagcgataca ttctcgaaca atcagaggtc tcaacggtct tctgctggca ggacggctat
    18181 gaagaactct gcgcactcca gtcggacatc cccacgttgc gccaggtcat tgcgctgggt
    18241 gatgccggtg tgctcgataa tcacaggacc ggaaaaaaat ttcacgcaca cggagcaggc
    18301 cgctcgcttc gccgctctcc gttcacgtca gggctcgacg atcatgcgct gatcgtctac
    18361 acctccggca cgaccggccc accgaaaggc gtcatcctga cggtggccaa tcttctgatc
    18421 gatgcggatg cgatcgcgag ctggcacagc ttcggtctcc atgatcgcct gatgtgcgtc
    18481 ctgcccatcc atcatgtgaa cggtatcgtc gtcacgctga tcacgccgtt gtactgcaag
    18541 ggcagtgtgg tgatgaaccg cagattcaag accaccagct tctggcgacg gattcatgaa
    18601 gagcaggtca cctcggtcag tgtcgtcccc acgctgctcg aatttctgct cgatgccgat
    18661 gaggatctca ccccctacga tctgagccgc ctcggcgggt tgatctgcgg cgccgggcct
    18721 ctcttgaaag atacggccgc gcgtttcgaa catcgcttcg gcgtcgtcat tcgccatggt
    18781 tatggcctgt ccgaaaccac ctgttactcc tgtttcctgc cgaacgatct gacgcaggaa
    18841 cagcaccgtc actggctcac cggctatgag cttccctccg tgggagtgcc ggttcgtcac
    18901 aacctcatga cggtcctcga cgaacgtgga cgcacgctgc ccccggccac ccgcggagaa
    18961 atttgtattc gcggacgcac cgtctgtgcc ggctatttta agcgcgatga cgccaacgaa
    19021 gccgccttcc aatggggatg gttccggtca ggagatgagg gattctatct cctcgatgac
    19081 agcggacggc cgttcttctt cgtgtcggga cgattgaagg aactcatcat tcgaggaggg
    19141 gtgaacattt ctccgctgga aatcgatgac gtgctgaaga cgcaccaggc cgtgaagttt
    19201 gcgatggccc tgccgttcga gaaccgctac tacggcgagg aaatcgcggc ctacgtggtg
    19261 cccaaagatc ccgcctccat cccgagcgaa gctgatgtgc tggcgcattg ccggatgcgg
    19321 ttgccttttt ccaagcaacc taaggtcgta ctgttcggtg atgatgtgcc ctacacctcg
    19381 acaggcaaac ccaagcggct ggagttgaaa gcgaggttgg caggaaggct ggcgcagtat
    19441 cgcgacacac agttcagaga tcagtgagtt gaacaggccg tgtgaggtca ttcatgagca
    19501 ccctcatcaa aggattcgaa cggatcgagg aagcgcggga gcgattgacc ggggcaagtt
    19561 ttctcgccgg actctttgac ggccggccgg acttcgagtt cctgctgacg ccccccgaac
    19621 caccggagga acgggcggcc ggcatggcct tctgtaaaca ggtcgaaaca ttcctacggc
    19681 aggaggtgga tccggacgaa atcgagcgtg aggcgaaaat tcccgacgcg gtgattcggg
    19741 gcttgttcaa actaggcgcc ttcgggatga aaattccgaa ggcctatggc gggctgggct
    19801 tctcctatac aaactatggc cgcgtcctta cgttgattgc gagttggagc aacattctcg
    19861 ccttgaccgt ggccgtgccg cagtccatcg gcatcgccat gccgatcctc ttgttcggca
    19921 acgaagacca gaagcggagg tatcttccgc tggtggcgac agaagcgctc tccgccttcg
    19981 cgctcacgga accaatgacc gggtccgatg ccgcgaatgt ccggacggaa gcgacgctcg
    20041 atgcgaatgg cagccacttc ctcgtgaacg gcgaaaaact ctggtgcacc aatggaccga
    20101 tcgcgcgtta tgccacgctc atcgcccgtg tcccggctcg acgagtggtt cgagagggac
    20161 agacgacctg gatgccggtg cctgaaggac agggagccga cgaccgggtg catacggcgt
    20221 ttatcctgga tatgtccacg ccgggcatgc aggtccgtca acgctgccag ttcgaagggt
    20281 gccggggaat tgaaaacgcc cacatgacga tgcaggaggt ccggattccg gtcgagaacg
    20341 tgatcggcga ggtagggaaa gggttgaaat atgccctgac gattttaaac gtggggcgcg
    20401 gcatcagcat cccggccatt tgtctgggca tggcgaagca ggcctggcag ccgactttgg
    20461 atcgggccaa cggtcgggtg acgtttcaca agccgctggc agaacgtcaa acccagcaga
    20521 ttcgcctggg cgacatggct gcgcatttgt ttgccatgga agcgctctcc atgctggtgt
    20581 ggcgactggc ggatcagcat cgtcatgaca tccgtatcga ggcggccgtc gcgaagattt
    20641 tctgctccga gcatacgatt caatttctcc gggacgcaca aattctgttc ggcggcatgg
    20701 ggtatgaaac cgcggcctcc aaaatggcgc gcggcgaagc gggattcggg atcgaacagc
    20761 tcgtgcggga cgcggagatg tatcgcatcg gtgagggagc cacggacatc ctgcgcccct
    20821 ttatcgtgcg tgaagggctg agtcaccatc tcgaccgcgc gaagccgttc tattccggcg
    20881 acctgtcgat tctcgaccaa ctcaagcagc tcgtgaaact ggggggattt tatgggccct
    20941 ggtacctgcg gcactgggta cggcactccc tgccgacggg ctcggccttt gcgcatccgc
    21001 aagtccggtc cgttgcccgg tatgtcgaac gaaccagccg gcgcctggcg cgggaaattt
    21061 tttatgcgat ggtgcgcttc caggctgcgt ttcaagatga gcagcgggtg cagaaccgga
    21121 tcgaatccat cggagaagac ctgttggcca tgatcgccac ggtgctgtat gccgagcagc
    21181 aaaccagatt ggagggacgc acgacggtat gggagctcgc agaggccttt catgtcgcgg
    21241 cacggaaacg gattacgcaa cgccttcgtg aaatccggcg ccattgcgac ggcgtcaccg
    21301 cggagaccgg acaacaagcg ctgaagggat attatcctgg cctgtcggac ggcatcgtgc
    21361 atcgacgttt agatgattac cgtcgcaagc aggccgtatc agaagcgatg ccactggcca
    21421 tggcatccgt gtccctagac gtgaaggacc ggtctctctt cgcgcctgtc aaggcgaagg
    21481 caggcgagag atccacgtga tcgctcactg agctaacttt ttccaagccc caggccggcg
    21541 atcacctcga ccttcaaggg ctggtcggtt tctcccatca acagggtgcg catggggaag
    21601 ggaatgtcga tcccctgagc atcgaaggcc ttcttgagac ggcgtcggta ttcgcgcccg
    21661 attttccatt gttcagccgg tttcgttttg attcgtgcgc gaatggtcac ggcgctatcg
    21721 gcaaaatttt cgacgcccac gatttcaatc ggctcgatga tcagcgaacc gaacgcctga
    21781 tcctggcgca acccttctcc cactgtccgc atcacttcga cgacccggtc cgtgtcctcc
    21841 cgataggcca cgcccatatc cagaacaaag gccgaccagt ctttcgtcat attggacaac
    21901 gtcgtgatgc cgccgttggg gaaaatgtgc accacgccgg agaagtcgcg tagcgagatg
    21961 gtgcggaagg taatcgtttc caccgccccg ccggtcccgt tgatcacagc cacatctccc
    22021 agccggacct gatcctccag aatgatgaag aagccgctga tcagatcgcg caccagattc
    22081 tgcgcgccga agccgacggc gaggcccaga atgccggcgc cggccaagat cggggcgata
    22141 tccaatccaa ccagctgcag cgattcaatg atgatgatcg cccaaattgc cgacagggcg
    22201 atggtccgga gaattcccgt caacgtggct gcacgcttgg cggcggttcc ggattcctgg
    22261 tcctgcttat cgctggccac aatcatcact cgttcgagct gatgcaggcc aaggcgcacg
    22321 aaccggattg ccacataccc gatcgccagg accaacccga tgcgcaaact ggcgatcccc
    22381 acggccgcgg acatcgtgat caaccaggcc aggatcgtgt ccaatgagat tccggtcatc
    22441 atgcaggcct ccaatttatg agcgcgaccg gcgcgcttct gcgatcacag ggagacggag
    22501 agtttcggcc gaatgccgcg cgacgctgca aatggcaaga agacgagccg gaacattcgg
    22561 cttagcgtca taccatcccc cgacgattct gtccaaggcc caattcctag ccttccaggt
    22621 tttcgtcagg caatcggtag acacttcggg ggcatttcag ttattatccg cgttctcttc
    22681 ttcacacgac cgatcgtgct gtggcggtgt agctcagttg gtagagcagc ggactcataa
    22741 gccgcgggtc acccgttcaa tccgggtcac cgccaccaat aaaccagcca gttagcgtga
    22801 tctgctacgg ctgcaatcag ttcaggttgc gcctgggttg cggatttgcc gtctctgttc
    22861 ccccattcga ttccgactat ccagtctcag gccccattcg cgatttccct cagggaaata
    22921 atcagaggca gtatctaacg tctacttttc aagattggct aaacgagtga cggtgatctt
    22981 tacctctctt aggaagagca gatcaccaga gatgaatctt cggaccacgg caaactgtgg
    23041 tgaatacaca gagctagtag ttgcggtgat tttgtgaggc gtcagcggta cacgtctttg
    23101 cgatggcgaa tactaagaac aatgagcgtc gtcgcatcaa actggtagac gatgcgatag
    23161 ttcccgatgc gatagcggcg gcaaccttca aacggcggaa ggagagccgt gcccaggagg
    23221 gggtcggctg ccaacgcatc aagcgccgcc tggacagctg ctcggaattt ctgcgggatc
    23281 gggcggagtt ccttagcggc cgactttgtc agctttacgt ttttgaacgg tgtcatgccg
    23341 tgcttctaga tgagtccgaa tccccagctt acgaaaaatg ctcattttaa gtgcatggat
    23401 ggtcttcggc gcgaggcgaa ggtcgtgggc aatctcattc tctagtgatc cggcggcaat
    23461 gcgatgcagc accgtcactt cgcgctcggt cagcccgcca ctccctatgt ttcctgggcc
    23521 ttcaagaggg gtatctttag ggggtgcagc ctcgcgatac gcatcctcgg ctgagaccaa
    23581 ccgcccggcc cgcacgtccg ccaggccagc ctcaatcgct gccaattcgt catggtcggc
    23641 catgacgtca agcgtctcta gccagctttc atattcggca tagcccatca agaccgcctc
    23701 gggtttgcca ttccgcgtaa taatcacgcg ggccatcgtc cgatttgctt gttccacgag
    23761 ggcacggagc tgctcgcgag cttcagagat agggagcgtc ttgaccatga attccacctc
    23821 tttacaattg tacaatattt tgtacgatca ccccttccct cgtcaactgg aaacggggca
    23881 tttcccatcg agcagaactg gtgcggactt tgtttgcagc gaagaggcat tatcggcagc
    23941 gtaaccgggt ggagaagtat agacactctg aactggggaa gacttggtgc tactgataca
    24001 cctttgtccg ccccatctat acggctattc tacttccgcc ttccggtatt gcgcggtaga
    24061 gtgagtgacc actcggcacg gtgtggagac gacagagcat catcgagttc agcgctcgtg
    24121 ggatgacgat actggcagat cgcactgaat tgataaataa ctaaggactc ggctgccgga
    24181 tggacgagac ggaactcatg ttcgacagct cccaaaccgt ggagcttact ttagaagcag
    24241 accgcacagc tcaatcagct agaaaagcga ttctcggcct atggaccctt cgcgagcgtc
    24301 ttcctataaa tttaccgaac cgcgagcttg ctcatatcga ttttcacgct gatcgctccg
    24361 cccagttcac cttcccttcc tccctccttg gaatatccgg agatatcgcg ctcgcctttt
    24421 ggttctccat ggcaactcaa acaattcttt tcgtaaaaga gcgggaggag aacccgcacg
    24481 ctgtttccgc catctacctt actgatcacc gtttccttat ttcgttggga cgaggcctcg
    24541 ctgagttcct tcatgtgttc cgcctcaaaa gagtcgggtt tattgttagc attgcgaacg
    24601 aggtgctcag gcgcggtctg ttttaaatag acaccagacc acttctgaaa acgggtcgcc
    24661 gtttccgtgc cgaaggtagc gggaatgagc cctttgtatt tcaacccttt catattgagc
    24721 acaggctgat agctctctac ggttttctta ctttccatca tgaggcgttc cagtaatcgt
    24781 ttcgccaaag tcggcacatt cgcattgggc aggtcatcca aattgtggcc ggtgcgctct
    24841 ttaaaaatgg cggttgcttg agcggcaaac aattccggag taaatgccgt ttgcgcgttt
    24901 gaaggatcat tgatcagtgt ttgattgcgt ccgatcgcca cccgtccgga atccagtaag
    24961 atggccagca accgaccggt ctccgacaaa tcggattcgg tattgtccgc cgctacgctc
    25021 atattctgag tcaggcacca tagtgcgacg aaacacaata ggtatacgcg catagtagcc
    25081 ctttcgtgcc gtataaggcc tgctggtttg ttcacccatg cttatgacac cacttctatc
    25141 ctgaacagga tgcgaagcaa gctgtagaaa tccctagccg cctgattgtc acgagaggca
    25201 tcggacaggc atgaacatca tatggtgatc tttcagcctg aacaatagga ctcactcgag
    25261 aaattttccg gcagtcgcta ctggatgagg cagagggggt cgcgccacct aaactggcaa
    25321 agagaagttg ttcctgttac acgtctgaag cgagcgatga ttaccagagg agagcctgcg
    25381 caatgtacga gtaggcgttc aggtacagag tacataggcg gcgtacaaac gtcggtatca
    25441 gggggaatag gagagatgtg atcggccgca atgccttatt tcgaagaaga cggcgattgc
    25501 ggcacgacca cgaatggaag aaagaccgag aaggcgcgat aatgcgtgca ttttaccgct
    25561 cggcttggct tcgcgcctac cattccttca accgcagcag ccggattcaa actgccgccg
    25621 ctggtaggcg aaaaccaggc agcggatgca gacctcacgc acggtcttcg tctgcgagtc
    25681 agacaggggc gttctgcgca tcacaagctg cccgcaatcg gcacaacaac cggctgtcgc
    25741 agcatccctt tcacaagaga cagacatcat ggcgttggac cctcctattt tctcgaacgg
    25801 gttgtgtggt cgtcgtatgg gacttcattc cacttagcag tgtgcgtaac cgggaacttc
    25861 cactccatcc ttgagtcaat cctttggtca gttgtaactc tcgctgcaat tccccgattc
    25921 gtccattcag ccggacaatc atccgttcga gttcatccac acgttcaacc atgatgtgtt
    25981 gctgctgagt cattatgtgc cctccttgga ctacgcgttg tcgcaatggc ggatgacccc
    26041 gaccaggacc ccttcgatgg caaattcatc cgtgggtgcc accagcaaag gcttcatcga
    26101 ggcattggcg ggatgaagtt cgatggaccg ctcccgcttg aagtaggttt taatggttgc
    26161 ttgcccattg accagagcga ccaccgtctg cccgttatgc gccgtggatt gtttcctgac
    26221 caccaccaga tcaccgggga gaatgccatc ctcgatcata gactcgcctt tcacccggag
    26281 cgcgaaggtc tctcccgccc gcaccatgct gggaggcaca tccacccact cggattgggc
    26341 taccggttca atcggcaccc ccgcggcgac cattccggcc atcagcacct gggatcgatt
    26401 gagcagttgc gtcatagcga cctcgaccgc tccactgata cgccgcattc cggattcgta
    26461 tcgagcgaca gagacccgag tcatccgcaa ggcctcagcc agctgctcct gcgtgagtcc
    26521 caactgctcc cggcaatttc gaaattgttt cggcgtcatc atgtaaccaa tggttacacg
    26581 cagagaacga tcttgtcaac ccatccacga atcattggca ttaatatact agacgcatca
    26641 ctatagaaaa ctgtggagag tccataaatg cacgcctgca attacagtga tttagacgca
    26701 cggagggagt cgaaccctcg accgccccat ccagagtggg gagctctaac cgctgagcta
    26761 cgtgcagacc aattattttt tgcgggattt cttcgtggga agggcggact tgggaacggc
    26821 gacgaccttg gagagcgcag ccgtgaatcg ttcgaacggc gtttgactcg ttcgatccgg
    26881 tggcgtactg tgctgctgca attttccgga catgattctc tccgcgttgg gtgtttcctg
    26941 ccagaaacgc ctagcgcaag ctgtacctta gcacaaggga gggagcatgt ctaacgcacg
    27001 ttataacgca gtggctcact tgcgagcctc gttaatactg agggcacacg acgctatggc
    27061 aatgctcacc gtctattgcg atgacagcgg cacagacaag aatagccgtg ttgctgtcgt
    27121 ggctggatac ctgagcaatg tggcccagtg ggaacttttc agcaaagaat ggaggaaggc
    27181 actcgatgag ttcggcattg atcgcatgcg gagagccgat ctagagaatt tccgaggtga
    27241 attcaagaag tggaatcctg aacggcgcat agcattactg caacgtttgc agccgatcat
    27301 aaaacgcagg accaagctac caatcgccag cgtagtcatc aaagaagact ttgaacgcgc
    27361 catatcagat gatttgaaag agaagatggg cggagtctat ggattcttgg cgtatatatg
    27421 cttggttagt gttggtcaat ggtgcggcag aagctctaga ttgcacggtg atcccattca
    27481 atgggtattt gaatctggga cagaaggtag tcaccaagtg agccagatgt ttgacgtcat
    27541 gtatagcgat gagcgattgc gtaataagtc acggttgggc ggatggtcgt tccagggaaa
    27601 agaacttgcg ccattacagt ccgctgatct ccttgcatat gagtgtttca agcatataga
    27661 aaatcaggtt gtggataggg gacggcggcc ggttcgtatt tcttgggggc acttagttgg
    27721 atctgaacgg tgcccatata tgaagttttg ggaaaagccg tggttagaaa aattctcgcg
    27781 agaattcgat caacggctga ctccgctcaa cacaaatatt cccccccatg ctcagtaaat
    27841 tccagatttc ctcttccctc tcccctgcct tctataatct tcaggcttag tgccacgtcg
    27901 tttgaccaat tagctcccga tattgaacac gcttgccgct aatctgtgag agtgcagcca
    27961 tgaatcggcc ctgatcatta tccttccgag tgttgaaccg gaaggcttgt tcatccaaat
    28021 atctgaacaa gtggaacggc tcaacgctga tataggtgcc tttgattccc cgctttaaca
    28081 ggctccaata gttctcaatg ctgttagtgt gaacgttccc tttcacatag gtttcagcgt
    28141 gattgatgac cttgtgcgca tattcacgac caaccttggt gtagcctgca gcttcatcgg
    28201 tgatgaggtt tgatccaggg acgacatgtt cccgcacaga tttgcctaag agcttttcag
    28261 aagcggtccg caagaccgca gtgcgcactt cccctttccg ctccaacatg ccgacgacca
    28321 cagccttacg gaacgagcct tcattcttca tgagcttctc ccgcttgtca tggtgcatgt
    28381 tgcgagcctt cccgccaatg taggtttcat ccacttccac atcacccatc agcttccgat
    28441 cgattgagcc atgttgtagc gcgagccgaa tccgatgcat catgaaccag gcagttttct
    28501 gagtgacacc aagactgcgg gctacttcat aggatgaaac gccattcttg gcattggtga
    28561 gcatccagag agcacagaac catttatcca gcttaatggg gctatcctcg aaaattgtcc
    28621 caactttcgc gctgtactgc ttccggcaca ttttgcactg atagatgccc ctcgacttca
    28681 catagccgtg ttcatgggaa cggcagttgg ggcaaaccgg accctgcggc cagcgcatcg
    28741 cactcagcaa gtcctgacag cgttgtggat cggcaaagta ttggatggct tcttgaagag
    28801 tggttggcag ggtcggattc atgggctacc tccgtattcg tgagcggagt atagccatat
    28861 tttaatgatg agtcaagtat attagtgccg aatcattttc ttgactattt tgttcgcctc
    28921 tcccagcgca gattttggag ccgggggcgg aagattttcg gcgaattcga caagcttctg
    28981 tgcataagtc aagagccatt tgggaagggc ggataaataa tatgcgtatc cacagccata
    29041 aactgaaaac cctgctccgc cgtacaaata tgaatgctaa tacatacaca tttcactacc
    29101 accaccatat attgtggttg cagcgcggct gttctctatg cccaataaat aggcaacctg
    29161 gtgtgaggcg tgaattagcg gtgctgttcg cattcgaccg gaggactatc aacagagata
    29221 tccacagatt ttggggagag gatttttttc acagaattct cgttttcttc attgaaacct
    29281 ctgaatcatt gacctagaat cgcgccgcgg cttcgtctca cttctacgca ggttggcacg
    29341 tcgggagcgg catcatggca ggaggctcac tccgaggttt cctggctgtt atcgtcctca
    29401 ccttcggctg cagcgccaac gtccgagaca cagatctctt ggccagtaac agcctcatgc
    29461 tggccccctc aaccgcccga accatcttcc ttcaaaatcg caattcgtcc gacaatcaag
    29521 acgtgtcgtt gcacgatctt ggcgcacgat tgggcgcgaa aggctaccag gtcgtccagg
    29581 atccccaagc cgcggcctat gtggtgctca cgaacattgt gtattgcaat cagaccaaga
    29641 tcgaattgcc ggtggaagag atggtcgccg gcgggtatgg atcgggaatt ggcagctcca
    29701 tcatatccgg gctccatggt ttgacgggca tggccagtat ggccgggccg cagggtgcgc
    29761 tggtcggagg tgccgccagc ctggggctga atgcggctga ggggattggc aacgccatgg
    29821 ggagtatgtt tggcggaccg tctcgtccca atgccaatga aaacattaac tatgcctgca
    29881 tcgccgatct gcaaatcacc gatttgcgtg ccaccggcgg aagccttccc gtatcccaac
    29941 cgggtacccc gcctccgtcc ggtgtctacc aaaccaggct ggcggccaac gtgcatcaaa
    30001 agaaacttga tgagcaggaa gccactccct tagtgcagca acgcctcagc gcggcagtgg
    30061 cagggcactt ttgatcatgc cgagcagcac agctgacatg agggcgatcc gctccatgag
    30121 cagggctctc agcctattcg tcggtctgct catgctgacc ggttgcagta atgtcttgcg
    30181 ttcgggactc gtcaatgatg gctcgattct cctgccccct agcgccgcac gaacgattta
    30241 cgtgcagatc cgcaacacgt ctgaaaacca aacggcgacc ccgacggata ttccatcccg
    30301 gctgagagca aaaggctacc aggtcgtcgc cgatccgatg gaagctgcct actggctcca
    30361 gacgcaagtc atctattgtc acaaggcggg tgagggcgta agaccggaag ccgtggctaa
    30421 agccggcttc ggggcgggta ttggcagcgg aggcacgcca ctcgcgaatg ccggcggctt
    30481 cgacatggag gcgatgggtg gtatgttcgc aggaatgccc ggtggtggtc tcaacgcgca
    30541 agccatgcgc gccatggcga tgggcggagg cggcatgccg gacatgaatg ctatgatgcg
    30601 catggcgatg aacggccgcg gcgggtatcc aggaatggcg ccaccgccac aaagtgacga
    30661 tgtgatttat ctctgcgtgg ccgacgtcct ggtcacggaa caggcaaaaa acggtccgcc
    30721 gcgcacctac aagatgcggt cagtcgccca tgttctgcaa aaacacctga acattgagga
    30781 agccacgccg attgtgcgcg acaagttcag cgccagcatc accggtccct tctagcgcac
    30841 ctctaatcgc cttgcctcga taccagatga accgctccgg ccttgatcgc agcagtaatc
    30901 acgagccctt gggtcagctt gaactcctcc accgtcgacc tggtcaccgt ggcgaccaag
    30961 gggaagccac aatccagagt gacccgcgcc gatgcgccca gcatggtcac cgattgaacc
    31021 gtgccggtca ggtgattacg ggcgctgctt ccagaagctc gcccctgttc gagcaccaca
    31081 tcctccgccc tgatacaggc gaacacgtca ggcccgatcg attccgactc gagcgccatc
    31141 agggtcgtcc cgttcacgct gacgcgcaac atgccgccgg tggcctcgat cacccgcccc
    31201 tttaccaccg tctcgactcc gacgacgcgc gccacgtccg cgttctgcgg acggctgaac
    31261 acgtcgatcg gcgccccgac ctgcaagacg tcgcctgcac tgatcaccgc catgacatca
    31321 cccaatgtca gggcctcggc ccagtcgtgc gtgacaatga tcgacggcaa ggccagctgc
    31381 tttagcagcg accgaagttc atcgcgcaaa tgtaatcgag tcggcgcgtc caaggcggac
    31441 agcggttcgt ccagcagcaa taacaacggc cggggcgcca cggctcgcgc cagcgccaca
    31501 cgctgctgct gccctccgga tagttctctg ggtttggcct gctccaggcc acgcagttga
    31561 aacagctcca tcacttcatc cacccgcttg ttgcgttctg cggaagacag atggttcagg
    31621 ccataggcga tattccccgc cacggtgtag gttggaaaca aggcgtaatc ctgcgacatg
    31681 tagccgatat gacgatcttg aggcggaatc cgaatccccg acgcggtgtc cagccacacc
    31741 cgtgacacaa aacggatggt gccttcttcc ggccattcaa gccccgccac ggatcgcaga
    31801 atggtcgtct tcccagatcc cgatggccca aacagaatca ggaccgtcga gccctcaatc
    31861 ggatagcgaa tctgcgcacg gatcggcgca cgaccgggaa acgtcttcac gagatggatc
    31921 gttatttccg cggccatgct gcccacacgt ttcgattgac ggcatacacc accagcaaca
    31981 cggcatagga caccacgaga aggaacaggg ccgttttggc cgcgccggca taattcaacg
    32041 cctgaacctc atcatagatg tcgatggaga ccgtgcgggt ggaaccttcg aggttgccgc
    32101 cgatcatcaa caccacgccg aactcgccca tcgtatgggc aaaactcaac acggcgccgg
    32161 tcaccaagcc ggctgtcgat agcggcatga tcagcctaaa aaaggtctgc agtttcgaca
    32221 cccccaaggt ccaggacgct tcgatcaacc gccggtccac ctgatcgaac gccgccgcaa
    32281 acggctgcac cgcaaacggc agactataga gtatcgaggc gaggagtaat ccttcgaacg
    32341 tgaaaggcag cggatggccc accaattcgg tatacagacg cccgaacggg ctgtgaggac
    32401 caatggcgat aagaatatag aaaccgagaa cggttggagg gagcacgagg ggcagcgcga
    32461 ccacggactc gatcaaaaat ttccaccgcc aacgcgagaa actcagccaa tacgcgatgg
    32521 gaaggccgac aaataggagc gccaccgccg tgaggccggc taacttacac gtcacccaaa
    32581 ttgcgatcca gttcacgcgc gcgccccagc cacgaccaga cgttcccgac cggcgccatc
    32641 gtaagaacac cggccgggaa gatcaactgc ctccgccgat tattttccga tcatcacctc
    32701 ggtggccttc accgcgacgg tgacttgatc gttgaccttg agacccatgt tcttcaccga
    32761 cccttcggta atggcggcca caaactccag cgtgcccacc ttcaccacta cctcagccat
    32821 cgcctgccct tcattgatac ggaccacgtt cccctgaaat tgatttcttg cgctcagctt
    32881 catgttcgac tcccttctat ctgtgctgaa gtgattcagc tggtttgtcg cccccttcac
    32941 ggtccttaca ctcaaaccgg atcccccacc gtctgccgcg ttcctcgtct tcggtacctt
    33001 cgatcgtacc catacccgcg ctggtgtagc cgcggacctc gccttctctc agcaaacgtg
    33061 aactgccccc gcacttggcc tgcatcaaat ccaacgcctg cttccgatag ggcgaaccca
    33121 tcggccctcc ccgatcctgc ttatagctgt acgtcaccac tcctccctgc gcggactcct
    33181 gctccatgag caccgcctgc gaacagccgg cagtcacgaa cagagcgccg cacagcacca
    33241 accaccagtg tttactttgg taatgtgaaa ccataccggg tcatgatctc ctggccttga
    33301 ggcccttgca gaaaactcaa aaagcttcgg gcgagttcct gattcttcga ctgcttcaga
    33361 atgaccgccc cctgctccag tggcggatgc gcctccgcag gaatttccca atagctgccg
    33421 gcactcttca tggctggggc cagcgccagc gaaagcgcga taatccccac atcgcaggca
    33481 cccgattcaa tgaactgtgc cgcctgagag atattctcgc ccagcaccaa tcgatccttc
    33541 acatcggcat agacttgggc atgctccatc gcggccacgg ccgcacgccc gtaaggtgcg
    33601 tgcttgggat tcgcgatggc aatcttcctg atcgtaggtt cccgcaggac cgtcagtccc
    33661 ttgttcacgt ctaaaggaga ggacttcggt gcccacagca ctatgcgtcc caccgcatac
    33721 cgatacaacg aaccaggcac ggtcagcccc ccttcctcca attttttcgg atacccgata
    33781 tccgctgaaa aatagaggtc gaagggggct ccctgctgga gttgtgcgta aaagttgcct
    33841 gacgacccca gcgacacctt cacgcgatga ccggtttgct tttcaaattc gccgatcaat
    33901 tccttgatcg caaagttgag atcagacgcg gcagcgaccg ccagctcctc ggctcggaca
    33961 ggactcaccg cacacaagat gagcaggatg atcgcgaaaa atcttctcat attcagtact
    34021 ccctagaaag ttgtggacac acttgcttgt cacggcataa ctctcactcg tatccacacg
    34081 ccgtcccgtc aacagacacc acaggatgcg caaaaaggcc gtccagcaag gccgcagcaa
    34141 gcgaagaggc gaatcgtact ctcgcggtac ggtgagcctc tgagggacgc gagaacgcag
    34201 ctggcggact ttttccgcat cctgctagaa gaagatttga tattgaacgc gtatggcatt
    34261 ttcaatcaag gtccccccca cggcatccag cgggaccgtc cccgatccag gaggcagcgg
    34321 cgcacttcgg ccgatggcgt atccccccgt accaaactgg gtattgctgt aggtcaccat
    34381 gatttgatgg tcataggttc cgttcaagaa ccagttcaac gacagatcgg cttgcctgat
    34441 gaggtcgtta gcagaattgg tgtcagggtc ccagtacgca taccgggccg ccacttccac
    34501 ggttcgaggg atcaaataat atccgccttg cacataccag cccatggcat tgccgaagtt
    34561 attcggggcc gtcgtggtac aggcggcgtt catacagggc aatcccttgt cgtgacgaat
    34621 gacatttttg aagtagaact cgccctggag tgagaacccg cgatatttga acacgccgtc
    34681 cgccgcccag gtggaatagt ccacaatgcc aagcccgagt tgccggccgt tgccgaacgc
    34741 cgccaattgg cgcctgatgt tgagattggc caaatcgagg ccgacaaatg cgttgtcgga
    34801 actggtattg accgccggat tataggagta tccgccaccg acggcgaatt gcggcgtttc
    34861 ggaataggcg agatcccctt ctccatatcc gggacgtcca agaatgttcc agttcaatcg
    34921 cgctacatac atgagtcggt ccacgtcgat acgcgtattc gcattcaaat tgcgctgatt
    34981 tgcaggacac cccgccggag aggggaaggg attgccactc gtctggccgc cggggcagcc
    35041 caccgtggct tcttcagacg tgaacgagcc cagtcgattg aaacttggac ccgctccgtt
    35101 gaacaccccg aagtaatagt tcacggggaa caattcttca tcgttcatga tcgtgatacc
    35161 gatgtcgcgc cgatcgagac cgctcgcggt aaaggcatcc tgcaccaagg ctcgttcagc
    35221 aaactgcatc gacgccgtgg aattgatttg agaccggttg aagtacacct tgtactgccc
    35281 gaactgcacg ttggcccatg gcaatttcgt gtacgtaaaa ttgacatcaa acagcgacaa
    35341 cgagcccggt gactgcgcat tttcggccgt ctccgcccgc atctggatgt agtatttgaa
    35401 atccgggtcg aagagatggc ccatgaaata aaaccgcagc cgccggacgt tgaatgaaga
    35461 ggcactattc tctgaccgat tggctcgata gtcaccgaac acgcccagga gttcgggaaa
    35521 gtttttggcc tcgccgggat ttctccaggc atcgttacgg aatcgttggg tataccggag
    35581 ttgagagcgg aatcggatct tgagaaaaaa ggcattgtca ttcatcgaga gattaaatcc
    35641 gcggtcgtac cagccgcgga aggtgggcga cagcaactgc gtccgctcct cggaatcctt
    35701 cacaacctgc tcgtattcct cctgggtaat catgccgctc ttgactgatc gttcgagcag
    35761 caatttgagc gacgggtcca tgctttcgac aaagacatac ttcccgtctt tttcgaccag
    35821 cttgccggta tcggctgcct cagtcacccc cgcagagaag aaacaagccg ccagtagcac
    35881 gacaatcccc agcaacacac gatgaccaga ccattgatca cgaaaaatat acagaccttc
    35941 cctgagtctc atacatggct ccatcactgt cagtgagttc gttgaacgat cggaggtgtg
    36001 acggcctatc caccgtcagc gaggcgccgt ggcaccagct tcacccgatt tcaagaattg
    36061 ccgaaaatcg accgccggca cgcgcttctc gtcgctcgcg taaaagcggc ccggttcgaa
    36121 atagatgatg tattccttcg gcgtgggcgg agtgagcgga tagttggtgt cgtaatcatc
    36181 cgctttcctc accgggatct gggtatggaa atactcgatc gtgaggtaca ggtaggggtc
    36241 gcgcacagcc atccacccgg caatcgtgtc tcgtccgtag gccggattga agccggggtt
    36301 gcgcacctcg aaatgcaccc ggtcgttggg gccgacgtgc tgaaatccct ctgcgagata
    36361 tggcgcgagc gcgtgcagat cgtcttcgcg aaacagcggc ttcggtggtt gctcttcagc
    36421 aaaccagcgc aacggcacgc gttgctgttc acgaattgaa aaccctcgca acagactggt
    36481 gagatcagca ctcgtcagtt gcactggatg cgaatacgtt tgaggttgca cgtcgcgctg
    36541 aaccgccacc acaacacgct gatcctcatg aattgttttg gtcgtatagg gcagcctggc
    36601 acagcctgcc gctgccaggg cccatatgag cataagggcg agaacagacg tccctcgcct
    36661 gctgctcctg attaatctgc tattcatcat gcctccttcg cacgatcaca ttgcattaat
    36721 acaaatatta aatatatgta tccttgcacc atgaacaaaa ttttttacgg cccgctcatc
    36781 gccggcaccg cataacctgc ttgtcgcacc agccgttgcg cctccgcact ctggatatag
    36841 gtcaggaatt cctcacaaag gcggcgattg gggcagtacc gttccatcgc catggaatgc
    36901 accgtcggct ggtagccctt gttgatgacg ccgacgaccc tcaaccgctg ttgctgatca
    36961 acagcctgat ccccgaaaat gatgccgacg tcggcttgcc cgctcaacac atggtcgatc
    37021 actccacgcc catcggtcgc catatccaac cgtcccttga acgcttcttc tatgcctgac
    37081 gcacgtaaca tatcggctgt ctgcgccccc aacctcgttc gcgttcgctc ggcaatcgct
    37141 agacgcgcgt ttccctgcgc gatcgcctcg agcgaccctg gagcctccac cagagactcg
    37201 ggcaccacta acaccaactg gtccacggca tacgagcgct tcgtaccggg caacacatag
    37261 tatttcacct gcaagcgcgt gatgacttca tcaccaccgg gcgccacgag attgatcggc
    37321 ccgctgccga cgaagtactg cccgaccatg ctgttttcca tcccggcgat cgtctggcgc
    37381 aatccgagtc ccgaatcgaa atacagcttc acccgcacct ccggatgcgc ttgctcaaaa
    37441 ccgctgccca atcgctccag taatcctttg aggctcggcg aagccgcgat gacaaatgac
    37501 tcggccgcat gagcctgtcc ggctccgcac cagaacacca cggccaaaca ccatgtagag
    37561 agaaaagctc gcactcgatg actcatgcgc cactgccctt tcatccatcc ctccaacgac
    37621 atcgtacaga gtcggatccg cctgctgctt ggaggcgcgt tatccgaccc gcaggctacg
    37681 taccttcccc gtctccgtca tgtcataccc gcccaacgcc tcgacttcgg ttctgaactg
    37741 gcggctggcg atagcgtcga ggagatggga aaggcctgga tgactggaga ggtatcgctt
    37801 cggcaagacc aggtcatacc gggcctgctg caacggcacg aaatcgagtc cgaagatctg
    37861 cgcagcggac cgcacgccga ttccgacatc cccatggccc tcggcaatat gccgtgcgac
    37921 ctcaaagtgc gagctgacgg tcactccgta ccccttcaca ctggtgccgt cggcgcctaa
    37981 cgcttcaagc cgctgatcca gcaacattcg ggcggcagca ccctcctcgc gattgaccac
    38041 aaccacattc gggcgaatga gatcctccac gcttcgaatt cgcttgggat tcccggctcg
    38101 gaccagaagc ccttcttccc acgccgcaaa ggtgacgaca atatagtcgt cgccctgtag
    38161 atgccgccgg agatagggca gattggactc gcccgttttg gcatcaagaa tgtgcaggcc
    38221 cgccatatgg acttccttgc gcttgagcgc ctccaatgcc gccgcgctgc ccatcgacca
    38281 gccgacgacc gtggaggtgt ctttatgacg gtgaagatat tcgctcgcga ggttgatggc
    38341 cggatcacaa cccgctaccg cgatttcccg ttcaacgatc tgccgctcac gcaacaagcg
    38401 cacgagcacg cgataatcgg atttcgccga acgtggacct gatcccgcct tcccgatgat
    38461 gagaccgtcc gcaggaacgg tgtaattcaa gatctcgccc aaggccgcca cgggacggac
    38521 gacgaaccgc tcctcaacct tggcaacctt gaccctggta cgcggttgaa ccgccgatac
    38581 agccagcccc ggccaaaccc aatctccttc gatcaactca ccggtcgtct tgaggctaaa
    38641 gatgtcctcg acgtggcaac ccagcacgct ggcaagtcga agggcgacgg ccgtggtcgg
    38701 gagatattga tcggcttcga tggcacagac cgcctgacgg gtgatcaagg ccccatccgc
    38761 aagctggcct tgtgagagac ctttggccat acgtaatgcc cgcagtgaat tcacgacatt
    38821 ggacgatggt tcagctttgc ttttttcact catgatggcg gacatgtatc atgatagata
    38881 aatttgtgtc aactatcatt gcagagtttc gaccagcagc aacgcaaacg tccagcggga
    38941 tctagagaac gtttcgctga ctgtgaaggc tctgcattgg gatcaatgca cctcagaaaa
    39001 gtcgtgtttg acggagccga aagagaaaga ggcattgaat ggttttattg ttgacaaact
    39061 tattaaagat aatatatttc atacctcatc ggaaattagt tatttaataa catgttgaac
    39121 ctatggtgat cgtaaccatt aaatcaccat ttactcagtc attctaaaca ttcacatggg
    39181 agcgaacgtg atgaaacgat cagcatttgc cctcggggta agcctggccg tcctctgggg
    39241 gagcctgacg ctaccggctc aggcagtcga ggaaggccag ttcatcaaga aggacggaaa
    39301 gtgggagtac tattcaggag aagaccccgg tctgaaatat ctcctgctca agggcatcat
    39361 cacccaggac gaatacgacc gcggccttcg agtcatcgaa aaacgcgaac aggtttcaaa
    39421 accgaactac acaatcgatg tgaacaatgg tttgaacttc cgcgtggggg acaaattctt
    39481 cctgaagctc cggctgctca ctcaggtccg ctatacccac agcgcctaca acagtgcctg
    39541 gggaacggtt ggtgattcgc gcaatcctga aattctcggc ggccaggtcg aataccgcgc
    39601 gatccggaaa cagagcgatt ccaaccaatt cagcgtaccc cgtgccagac tgcaattctt
    39661 gggttatgcc ttcgacccgg attttcgcta caacatttcc tgggcgttcg atcaaacaac
    39721 ctggaaccag gaaggcggga gcggcagagc cggcctactc gatgcctatg tctcgtcgtg
    39781 gcacattccc tggcttacgg tgcaagccgg tcaacagagg gtctggttca atcgcgccac
    39841 catcagctcg atggccacat ccaccttcgc cgacaacctg atcgtccaaa acgccttcgc
    39901 ggccaaccag caaaacgcgc gcgacgtcgg tgtcagcatt tccagcgacg aggatcaata
    39961 caagttcaat tatgcgttcg gtatctgggg cggagtgggg gcgaatctcg caagggaagg
    40021 cacctcggtc agccaaaatg tcttgcccca gaccggcacg ccgggggccc ccggcgcggc
    40081 gactacacga acctataact acgacacgcg cttcatgacc ggcgagatga tgtatacggc
    40141 ccggctattg tacaaaatcg cgggaaaccc cggctacggc cagggtgaca tcttgaactc
    40201 gcggacgctg cagtcggcaa tcgcattcgg ctatgcgtat aacccggcgc aaaactatct
    40261 gagctcgatt cgctccgata ttgtcgatcg ggcctaccgc caggccgtcg taaaggccta
    40321 caacggtcga ctgctagccg gcggcatctg ggattttcag acctatgaag cggacttcat
    40381 cgcgaagtat cagggctggt cattccaggc ggaaggctac taccggcacc aacgcttgcg
    40441 aaacgccaat agcggtacca gcgcgttcga cctgaacacg atcccggcgg cgcaatttct
    40501 cggcccggca gtgaacctcg gccaggcgta tggctggtat gcccaagtgg gaaaatacat
    40561 catcccgcgc aaactcgaac tcgcggtgcg gtatgggttc atggatccat ccacccaaca
    40621 ggtgaacgat ctggtcaaag aattcggcgc ggcgatcaac tatagtttcg acggcacgta
    40681 caacaaccgc ctcgtgatcg attattcgaa catcacgatg ggcagcgggg gacgagcgcc
    40741 ggaccggttt ccttttgaaa gccaaccggg attcggacgt gatctcgtcg agaaccggat
    40801 taatgtgcaa taccagttct acttctagaa atctatgaca cgccattaca ggtttttgga
    40861 ggacatcatg agagcagcat ttcgtatcag aggactcatt gccatagtcg gattcttgat
    40921 cagcctggga ctgaccgccc agccggccct ggcgcagccg gaaaccatca ccatcgccgc
    40981 cgccaacagc ctcaaggacg cgcttcgaaa ggtgcttccg ctgtttgagg cagagcacag
    41041 gaacatcaat gtgcgggtga tttacgggcc gtcgcaaaca ctccgcagcc agatcgaaca
    41101 gggcgcgccg gtcgatatct ttctgccgtc gctcttcgaa gaaatcgatc agctcgaagc
    41161 gaaagggctg atcattcaag ggaccaaacg ggcctttgca gcaacgtccc tggtcttgat
    41221 tacgggaacc gccctccccg cccccatcag cacgattcag gatttgcaaa cgatcccgat
    41281 acgacacatt gccgtcgggg acccgaagac gtcatcggtg ggaaaagttt cagcgcagtt
    41341 cttgaagtac agcaaactcg agccaaagct gaagtcacaa tacgtcctcg gtgaacactc
    41401 tcgagccgtg ctcgacctgg tggccaaggg cgaggctgaa atcggcgtgg tctatcgcac
    41461 cgatgccatc tccaacccgg gcgtgcgcat tctggatacc gctccggtcg gctctcacac
    41521 cccggtacgc tacggcgtcg ccgctgcctg gacggcccag aacatcaccg cggccggcga
    41581 tttcattgaa tttttactca gccccacgat ccagactcaa ttgcaggaat tcggattcga
    41641 ccgcgtatcc cccgaagtcg gattcgctca acgagaagag gtgaaaccat gaacggcatc
    41701 ggacatccac agcagcattc gctatcccgc cacaccaatc tgatcctcgc cttcatcggc
    41761 gtgatggtgg cggccggttg cgcagcacca actccgacgc cgcccaaaac ggtttaccag
    41821 tcgggattga atcaagtgcg aatcgagaag gatccggcgt caaccatcaa cgcccatccg
    41881 gcctcattga gcgccacgga agtcgggacc ttgttacgag gcgtgcgagt ctgggaacga
    41941 cgcaacgcac tgcaccggct ctttgtcgga ccggccgaca aaatcagagc cttccgcgac
    42001 ggagaaattg cgatcctggc gccggcgttg gcaaaagcgc tgtcgcaagc ctcgccttct
    42061 gaacgcgtgt actaccatct cagccatgcg accgagcatg gcgaagagga gaccagcacg
    42121 ggatggctct cgatacaaga cgcgacgctg catctggcgt tgcgcgaagc ccacgaccgg
    42181 catgggccgg gacccgatat cagtaagtat gaccggcaga tgccgaacgt gccggaacgg
    42241 tctccggcct tcgacgccac ctttgagccg gaagaatacc tggtgaaggt ccggtcaggt
    42301 ggaagtctct tcgcaccgga tcagcaggaa gaattgctca tccgataccg ggaggcgttg
    42361 gctgccatgc ccgcgcaacc gggattggaa cgagagagca aaccggtgcc ggaacggcac
    42421 tgagcgatcg agaaggaagg agcatccatg gcaatcctgg tcgtcggcgg tgattcggtc
    42481 agcgccatca cagaacgggc ctacgccggc ggccacggat gcgtccaaca ttggagcgga
    42541 cgcaagacca gggatctcat gaggtcgatt cccaaagata cggaggccgt ggtgctggtg
    42601 ctggatcgag tgaaccatac attagccagg aaagttcgaa ccgaagccac acgccgcggc
    42661 ctacccgtct tttttcagaa gcgagggcgc caagttcggg cggccggtga ccggccgctc
    42721 gacgtggtgc actggctcga cacaaaagac accggtctac gaaaacatcg cctggaccta
    42781 aagacgccag catagtccgt ccacttcgta tcatggcgat tgaaccttcc acgtgaaccg
    42841 acagaaaggg gaagagaggg caaaccacat gaccacattc caaacgccga ccatctcagc
    42901 cctgagggtt ttctacgcac gcatgtgcgt accgcatccc tgttgacctt cgaccgtccc
    42961 tactgattcg aacagcgtgc cagtgaagaa ccgtgaagca ggtcgccgat ctgccgaatc
    43021 gatatccgtg cgtctttatg aaggagagat catgatgact ttcgcacatg tcgctagcgc
    43081 cctcgcgatt gtactcgcgc tgaccaccgc tgcgctggct actgagtcgc cctcgctatt
    43141 aaacgtgtcc tacgacccta cccgcgagct gtaccaggaa tataacgccg cctttatcaa
    43201 acattggaag gaaaagacgg gcaacacgat cagtatcaag cagtcgcatg gaggatcgag
    43261 caagcaggca cgggcggtca tcgacggcct cggcgccgac gtagtaacgc tcgcgctcgc
    43321 gcaggatatc gacgccattt cccaccaggc cgggctgctt ccggaaaact ggcagactcg
    43381 cctcccccac aacagcgcac cctacacctc gacgatcatc ttcctggtgc gcaaaggcaa
    43441 cccgaaaggc atcaaggatt ggagcgacct ggtgaagccg ggcctggcag tcatcacgcc
    43501 taaccccaaa acctccggcg tcgcccgctg gaactactta gcagcctggg gttatgccct
    43561 taagcaggcg ggtggcgacg aaaccaaagc gcgggaattc atcacccgac tctatacgaa
    43621 cgtgcccgtc ctcgactcag gcgcgcgggg tgccacgacc accttcgtcg agcgtggcat
    43681 cggcgatgtg ttgatcaact gggaaaatga aatcctcctg ggcggccaag aattaggcaa
    43741 agacaaattc gacatcatcg tgcccccgac cagcatcctc gcggaaccca cggtcagcct
    43801 ggtggacaag gtcgtcgata aaaaaggtac gagagaagtg gcgcaagcct acctggaata
    43861 tctctactcc gacgtggggc agaacattgc cgccaaacat tactatcggc ctcaatcagc
    43921 cacggtggcg gcccaatatg ccggtcagtt tccgaagctg accctgttca ccatcaatga
    43981 agtctccgga agctggagtg tgaccaacaa ggtccacttc gtagacggcg gcctgttcga
    44041 tcaggtctat caagagattt cacgcaccag aaagtgacca cccttgtgcc ggtccggccg
    44101 atgatccacg ttcaccggcc ggatcggcac gcatggccac tcaaggagcc atcatgtcga
    44161 tcttgttgaa acagccgacg gtattaccgg gcttcggcct cacactcggg tttaccctgt
    44221 tctatctcag cctgatcgtg ttgattccgt tggccggtct gttcgtgaag acgtctgcgc
    44281 tgacctggga ccaattctgg caggccgtct ccgacccgcg gacggtggcc tcgtaccaat
    44341 tgacgttcgg gctatccttc gtggccgccc tgatcaatgc cttcttcggc gtcatcatcg
    44401 cctgggtcct cgtgcgctat gccttccccg gcaggaagtt cgtggatgcg ctggtcgatc
    44461 tccccttcgc gctcccgacc gccgtggccg gcatcgcctt gaccgccgtg ttctcggtga
    44521 acggatggct cggccaatat ctggagccgt tgggaatcaa ggtcgccttc acgccgttgg
    44581 gtgtactggt cgctctgacc tttatcggcc tgcccttcgt ggtgcggacc gttcagccgg
    44641 tcctgcagga tctggaaaag gaaatcgaag aggcggccgc cagcctcggc gcgacccgct
    44701 ggaaaaccat ctccaaggtg atctttcccg aggtgttccc cgcgctgttg accgggttca
    44761 cctcggcctt cgccagggcg ctgggagaat acggctccgt cgtcttcatc tccggcaaca
    44821 tgccgatgcg gacagaaatc acgccgctgc tcatcatcac gaaactggaa cagtacgact
    44881 atgccggggc ggcagccatc gcggtcgtca tgctggtggc ttcatttgtt ctgctcctga
    44941 tcatcaacgg gctgcagtgg tggagcggca ggcggcaagt cgcgttgtaa gcgacctggg
    45001 agggattatg acaaccggta tcttgggtct ggacatacgc acgccccgca ttgcctcgac
    45061 cgtcgccgag ccgttcctcg tgcgcctggc gctgatcctg gtttcgttga cgtttctggc
    45121 gctgttccta ttcgtgccgc tggcggccat tctcttcgaa gcgctcaagc acggcctcgg
    45181 cgcctatctg gcctcgtttc aggaaccgga tgccatcgcc gccattgaac tcacgcttct
    45241 cgccaccgcc attgccctcc cgctgaatgt cgtcttcggc atagcggccg cctgggcgat
    45301 cgccaaattc gagttctggg gtaagcaggt cctgatcacc ttgatcgacc ttcccttctc
    45361 cgtctcgccg gttgtcgcgg gattgatcta cgtactgctc tttggtttgc aggggtccct
    45421 cgggccctgg ctggccgcgc atgacatcaa gatcatcttc gctatccccg gcatcgtgct
    45481 ggccaccatc ttcgtcacct ttcccttcgt cgcgcgcgaa ctggttcccc acatgcaggc
    45541 gcagggcaag gacgaagaag aagcggcgct ggtgctgggc gccaccggct ggcagacctt
    45601 ctggcgcgtg accctgccct ccatcaagtg gagcctgctg tacggggtga ttctctgcaa
    45661 cgcgcgcgcc atgggagagt tcggcgcggt gtccgtcgtg tccggccata ttcgcggcga
    45721 aaccaacacc atgccgctgc atgtcgagat tctctacaac gaatacaact acgtcgccgc
    45781 atttgccgtc gcctccctgc tggccttgtt gtcgctggtc accctggctg ccaagagcct
    45841 ggtggaatgg acctcgtcgg tcgaacagaa ggagaaccgc ccatgagcat cgaagtccgc
    45901 aacgtcacga agacctttca aacgtttact gcgctgcacg agatcaatct gcacgtgaag
    45961 accggagagc tgatcgccct gctggggccg tcgggatgcg gaaaaaccac gctgctgcgc
    46021 attctcgccg ggctggaggg accgaccacc ggatcgattc tgttgaacga tcaggacgtc
    46081 accgatcgcc atatcggcga gcgcggcgtc gggttcgtct ttcagcacta tgccctgttc
    46141 cgccatatga ccgtcttcga gaacatcgcg ttcgggctca gagtccggcc cagagccacc
    46201 cgaccccctg atgcagccat cgacgcgaag gtgcgcgagt tactcaagct ggtgcagttg
    46261 gagtggctgg gcgatcgata cccgcggcaa ctctcaggcg gccaacgtca acgcgtcgcg
    46321 ctcgctcggg ccctggccgt cgagccgacc gtcctgttgc tcgacgaacc cttcggcgca
    46381 ctcgatgcca aggtgcgcaa ggaacttcgg cgctggctgc gccggctgca caacgacctc
    46441 catgtgacga gtgtgttcgt gacccacgac caggatgaag cgctcgaagt cgctgatcgc
    46501 gtggtcgtga tgaacaaagg ccgcatcgag caggtgggaa ctccggaaga ggtctatgat
    46561 caaccagcca atccgttcgt ctacgacttt ctgggcggcg tgaatctctt ccatggccgg
    46621 gtccatgaag gccgcgtcca ggtcggcgaa ttgaagctgg cactccgcga ggaatcggag
    46681 gtccccgacg gtccggcgat cggctacgtc cgtccgcatg aaatcgacct gcaccgccaa
    46741 ccaggagaag agggtgcgat cgaggccttg gttgggcggg tacagccggt tggagccgtc
    46801 gcgcgcctcg aaatggttcg actggacaac ggggatgtca tcgaaggaga agtcagtcag
    46861 gaacaatggc gctcactggc cttgagcaag ggagagcggg tcttcgtcag accgaaaaac
    46921 ctgcgtgtct tcccggaggt cgcggagtaa gcccatgcga gatccccgtc tcgacccgga
    46981 agcggattac gacttgccaa cggccgataa gccggactcc cgcgtcgcac ggccgagcaa
    47041 ggtcctcagc gcctcggacc cgcaggcgat ggtccaatcg atcagggcca gctgtttggt
    47101 cttcgaagat agcgcctccc aggccctctt gcagcgcgtg cgtcgcatcg cgccaaccga
    47161 aactacggcg cttatcatcg gcgaaaccgg caccggcaag aaactgatcg cccggcatgt
    47221 gcatgagttg agcacgcgcc gcacgggccc cttcattgcc gtaaactgcg ccgccatcac
    47281 ggagtcgctg atggagagcg agttgttcgg acacgaacgc ggggccttca cgggcgcctc
    47341 ctccaccaaa gccggctggt tcgagacggc acaaggcggg tcgctgtttc tggatgaaat
    47401 cggcgacttg cccttagccc ttcaggcgaa attgctacgg gtgattcaac agcgggaagt
    47461 cgtgcgcgtc ggagcacgcc ggccactccc ggtggatgtc cgattgatcg ccgccacaaa
    47521 cgtgaagctg gaggaggccg tcgccgcagg acgattccgc gcagacttgt attaccgcct
    47581 gcacgtcgtc acattgcagc ttccgccctt gcgtgagcgg cgcgatgaca ttcttcccct
    47641 cgccacgcat ttcctgtcgt tgtatggatc gcgcctcgga tttacccagg ccaggctctc
    47701 gccggaagcg actgatcagc tgctccaata cccttggccg ggcaacatcc gcgaattgga
    47761 aaacacgatt caccatgcat tagtcgtgtg cccggggacg gagattcgtg tcagcgatct
    47821 gcgcctgcca tccggacagt atgacgtgca tgtcaccaag cctgccgcag aaacagctct
    47881 caccggttta gaacaggcgc tccaatcact ctttcaagcg gaccatccgg ccctgcaccg
    47941 acggattgaa gagacggtgt tccgcacggc ctacgacttt tgcgatcgga atcaggtccg
    48001 cactgcccag ctcttgggta tcagccgcaa catcgtccgt gatcgtctga tccgctacgg
    48061 attgctcccg tcattggccc ggcagtagat ggatcaggac aggaggccag cactttgccc
    48121 tatgcggcca gcagcgattc agaagctccg gcacgatcgt cactgccatc ttcgcggagc
    48181 cgccgttgcg ccagacgacg cttctcggca tccgcctcat tcgcgagact cgttatcagg
    48241 ccccagacca ataccgtcag ggacaaggct ccaataatca gcacgcccat acgccacctc
    48301 ttgccttcca ttgatgaacg aacctcttct cattgcggaa cttcagcaac atcgacagga
    48361 atggcagcaa cacaggcgat gaaagactcc tccgttcacg ctggaacctc ctcgtcctga
    48421 tacgttcgga gcaattccat aaagacgccc atgcctctct cactgaggct atgcatcagg
    48481 tgaaatcgga aatgaccgtc aggatcgagg agaaacgttc gcgctcgtcc ccatgatctg
    48541 gcagtggcac cgccgaacag tcgttggaga cggcccagtg gatctcccac gacagggata
    48601 cggacatgag gcaggctcgc aaacgagtca cgaggccacc ggcccgcatc catcgagacg
    48661 aggacgagag tagcacccaa taattcgaca tcggttgcgt accgatccaa cagatctgcc
    48721 tcaatcacac cgagctttgg cacgaaacac accgccaccc atcgcccgcg atcaagttcg
    48781 agcgtcttgt acgtcaacgc tccattgatg attgtcggaa gtcgataggt gcgtgcttta
    48841 tcgcctagac gtgacatatc ttcctccttg ctccaaccgc ccttcagccc ggggcagacc
    48901 atgtcggagc gttattgtac tgccgagggg gcacgctcat gggcacgtcg gcacgacccg
    48961 tgttggtcct cgcgcaatcc ttcctgcccg atgcttcgga cagaaattag atagtcacca
    49021 ttctgcggcg gagaaatcac cacctggccg ttccggctca aacgatcgat cgcaaagagc
    49081 aggcgcgcct cttccagttt cggaaacagc cgactcagat agtcgagcgt ctgggggcca
    49141 ttccatctca ggttctcaag caaccaggca tccaccagcc ggctatcggc ttgatgagcg
    49201 ctgtcggtac gcgtatgtga ggacatgtcc acctccatgc tgagcaaaaa tatcgtacgt
    49261 cacgccccgg cacgaccaca tagggttgtg cgccgcgaga gaacggccgc tcagagttct
    49321 gcactcacgt cacaggccta tcacgcgcaa tcgagccaac aacccgggaa tcgacaaggg
    49381 aaacaggtcg catcggggaa ctgttggtga gaagcgttca tccggaggtc cttggcaaat
    49441 gaacgattgc cttcatctcg aatggcgcgt cgcactagcg cacctctgca ccgaccggct
    49501 ctcgtgatcc gatcaaggcc tcgaacaact ggttaaaatc cgcttcggca gtccgaacaa
    49561 acacaccccg acttccgccc acggcaatcg tgaggtcgcc tcctgaatag gcccagcctt
    49621 gctgtgggat ccaattgaac ccgctcagcc tggaatgggc cgcggctaag accccgagta
    49681 actgactgat ggccgcggaa aactgcgccg ttaatagcgc cacatcatca ggcaaggggg
    49741 cgccatgcga gcgaaaggca atgagtcttc cgttctccgc aaactccccc gaggcaatca
    49801 cgcccttgag cgtgagcagt tcatctaatg actttgccat gtgattcatc ctttctttag
    49861 cgagcagcaa cggtggggac tctgtgtgcg tggatattgc agaaggcgtg ttgttcaaga
    49921 gacggaggaa ttgaagctgt gaacgcctct gctgttggct gggcaacagg cgttgctggg
    49981 accgtgttgc tggagcagca gttgcaacgg tgcgtgacga tttcgatctc cctccggcag
    50041 aagaaccttc cgagacatgc tcatgccgca gagtggcacc gggataagca ctgtggtacc
    50101 gtaggcgctc acacgaggcc tgcatgcgct ggctccatga ccg
//
LOCUS       DAOQPD010000020        49855 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_267_length_49855_cov_20.862289, whole genome shotgun sequence.
ACCESSION   DAOQPD010000020 DAOQPD010000000
VERSION     DAOQPD010000020.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 49855)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 49855)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49855
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_267_length_49855_cov_20.862289"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..190)
                     /locus_tag="PK063_06890"
     CDS             complement(<1..190)
                     /locus_tag="PK063_06890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HMZ96808.1"
                     /translation="MLEWLANPEIWIALGTLTALEIVLGIDNIIFLSVLVSRLPESQR
                     AVARRVGLGLAMIARLGLL"
     gene            complement(359..1204)
                     /locus_tag="PK063_06895"
     CDS             complement(359..1204)
                     /locus_tag="PK063_06895"
                     /inference="COORDINATES: protein motif:HMM:NF012780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HMZ96809.1"
                     /translation="MTTAHGSHVSDYMHRQLEVVPQDTSVVTVATRMRTRSIGSVLIE
                     SFDRPHNDCRIAGIVTETDLVSKVLAAGRVPSRTSMADIMSSPLITIAPDRPMVDASH
                     LMQGKNVRHLVVTEGTDVLGVISVRDLVRHFVDADGGPVQALTNVYRPLSVLMQKAIE
                     TIGSEETAMAAAQRMADKHIGALFVIEADELVGIITEGDLVRKLLAYQLDPEAMRVGA
                     LMNSPLLDIDINRTIRDASERMAAKRIRHLAVTEHEKIVGVLSIRDLVKMVAIRDRPD
                     FLRRS"
     gene            complement(1305..4085)
                     /locus_tag="PK063_06900"
     CDS             complement(1305..4085)
                     /locus_tag="PK063_06900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-transporting P-type ATPase"
                     /protein_id="HMZ96810.1"
                     /translation="MPELTALEICRLAPSQVFRALATSPQGLSADDVRRRTLKHGPNS
                     LQALRRTPLIGRFARQFTHFLALLLWVAAGLAFLADAFHAGEGMATLGRAILGVILIN
                     AIFAFFQEYRAERAVQALRGMLPAKAWVIRDGQQQQIARSELVPGDVLVLEEGEQVPA
                     DARLTEVSGMRMDNSSLTGESKPQRRTAEPITDGHPLDIANLAFAGTTVLSGHGQAVV
                     FATGLSTEFGKIAHLTTSVQSGLSPLQQEIVKVTHVVAGLSVAMGLVFFAIGVSMGLG
                     FLSSAMFGIGIIVANVPEGLLPTVTLALAMGSQRMAARKALIKHLASVETLGCTTVIC
                     TDKTGTLTENRMRLDKLYVDDLIVESRESCLFSRNRLISAAESERWRPLFDAMIHCNN
                     AKRTRRPDGRSQATGDPTETALLEFAADHGLLHRPPLRRMGEWPFDADRKRMTTLHWS
                     EGRLLAFTKGAPESVLPRCTMQQGSSAAAELTPDGRKKILAQSQTFARQAYRVLALAM
                     REVERGVDELEADTLEQGLTFLGLVAMMDPPHREVPDAIQKCRKAGIRVVMITGDHPM
                     TAQAIASKIGLAPETPVAQPGRFVPVIEGAQVDTFSDEQLRRLLTPTAPGEPDPIFAR
                     MAPRHKMRIVSVLKEMREVVAVTGDGVNDAPALKMADIGIAMGAAGTDVAKETASMIL
                     LDDNFATIVSAIEEGRAVFLNIRKFMTYVLASNVPEVVPYLAYGLSSLPLALTVPQIL
                     AVDLGTDMVPALALAAERPHSGVMDEPPRPRTERLLNRDVLIRAYAFLGLIEAGIAMG
                     GFFLYLHSEGWTWGDPLDWNSPLYKEATTVTFAGIVAAQVANVFACRSDRFPAFQLGW
                     VSNPLLLLGVAVELTLLFIMTYSPLGHLILGTASIPAWIYGPLVLGAIGLLLADGFKK
                     SLSGRMRTRQAG"
     gene            complement(4078..4983)
                     /locus_tag="PK063_06905"
     CDS             complement(4078..4983)
                     /locus_tag="PK063_06905"
                     /inference="COORDINATES: protein motif:HMM:NF012791.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016208 - AMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HMZ96811.1"
                     /translation="MNMLIAVDGSEFAEWSVQMLEAIAGRPPDTVTLLHVVDSASLKS
                     SARKHAAVSKQAIAAMTKAGDQVLRRFEGLAKTALKQATTKPRTTIDTLLAHGRVADT
                     IAKVAKQKKADLLVVGSRGLSDAEHYLLGSVSRKVSALAPCPVLVVKRPLTSLSHVLV
                     AADTSKHSQGACSFLCKQFLPDSARVTVLSVVEPAVTELASKYLSRDQVEQISAPKRQ
                     AAEQLVEKLRARFLAEGYAVTPEVQFDHVTDALLRQATSRSIDLLVAGSRGLTGSERL
                     QLGSVSETLLKYAPCSVLIVRGWRA"
     gene            5310..5846
                     /locus_tag="PK063_06910"
     CDS             5310..5846
                     /locus_tag="PK063_06910"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96812.1"
                     /translation="MVKTYLMALVGGCMVMSLALTADASAGGSTVVAHVLSDEEAVEL
                     EIPTDIGVQKERLPLYRLGAVRYFSAGIGQVERTASYPLFSLKLVFTAGGKPFVSGVA
                     VTLRQPKDGTVLTIPGEHNTGPWLFIDLPDGTYQISATLGGVTQQVNNLTVRRGHVIT
                     QHVRWAEDRSPALPAQAE"
     gene            5889..6362
                     /locus_tag="PK063_06915"
     CDS             5889..6362
                     /locus_tag="PK063_06915"
                     /inference="COORDINATES: protein motif:HMM:NF012780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HMZ96813.1"
                     /translation="MVTKRKALAKRSASAGRKPVRFEDLTVKDIVNQRVQSARLDLTG
                     MKVASLLLKAGGTVPVIDTSKQLLGVVSEHDVLLALDEGQAWGTRTVRDLMSANPYSV
                     RPETSLPTLAHVLTESDLLAVPVVNDKNRLLGMVTRRDVVRAALRPAAKRRSAAG"
     gene            6396..6830
                     /locus_tag="PK063_06920"
     CDS             6396..6830
                     /locus_tag="PK063_06920"
                     /inference="COORDINATES: protein motif:HMM:NF012780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HMZ96814.1"
                     /translation="MRRIDLLTQACDPATLTVGQLMQDALFTCTPRTDALTIGRLMTK
                     QNFGGLPVIGEHGDLVGLVTEYDLLQAMIEGRDLRKVLAADIMTTHPLTAREDMRLEE
                     VANLFQDRYVTRLPVVRGALLVGIVARRDLLHGYMKASEYWS"
     gene            7298..8161
                     /locus_tag="PK063_06925"
     CDS             7298..8161
                     /locus_tag="PK063_06925"
                     /inference="COORDINATES: protein motif:HMM:NF013868.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HMZ96815.1"
                     /translation="MEKRTKLAEIVRNQQDTILKDWVDFQLNAITVRRDLMKDSELRE
                     QSREFLNLFTQAAQTGSDVSEAIWKPVKDFLGQITRSRVLLGFTPSETATFIFSLKQP
                     LFDVIRAAVKDPKDLVSDMWTTTTLLDKLGLYVMELHQQNREEVIHRQQEELLELSTP
                     VVQLFENILALPLIGTLDSARTQVVMENLLQRIVETGATISIIDITGVPTVDTLVAQH
                     LLKTVAAARLMGADCIISGIRPQIAQTIVHLGVDLSEVTTKATLADAFMIALQRTGAT
                     VTKSAATRSKG"
     gene            8164..8553
                     /locus_tag="PK063_06930"
     CDS             8164..8553
                     /locus_tag="PK063_06930"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HMZ96816.1"
                     /translation="MERIPILKMGNFLLVTVQVDMHDRLAMTLQDDLTGRIVKDRAHG
                     VLIDISSLEIVDSFIGRMIGNIASMARVLDAETVVVGMRPAVAITLVELGLSLPGVRT
                     ALNVDQGVELLKESIEERAQGNGHVAG"
     gene            8534..8938
                     /locus_tag="PK063_06935"
     CDS             8534..8938
                     /locus_tag="PK063_06935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010883997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma regulatory factor"
                     /protein_id="HMZ96817.1"
                     /translation="MATLRDEIYPIRSSDDIVKVRQITREWALMQTFSLVDQTKIVTA
                     ASELARNTLEHGRGGEVRIQALQEGPRRGLRLTFTDQGPGIPDLAKALQDGYTTGNGM
                     GLGLSGSKRLMNDFDIQTEVGKGTTVMIARWK"
     gene            8944..9978
                     /locus_tag="PK063_06940"
     CDS             8944..9978
                     /locus_tag="PK063_06940"
                     /inference="COORDINATES: protein motif:HMM:NF018884.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein/SpoIIE family protein
                     phosphatase"
                     /protein_id="HMZ96818.1"
                     /translation="MIKEQQMAGDQVQVPVGESTRVAEARRKAVELAGRIGLDETKTG
                     TCAVIASEMGTNLVKHATDGEMFVRSVTQGTMQGIELVAIDRGPGMSNVSHALQDGTS
                     TAGSSGNGLGAMMRMAAEFDIHSLPGRGTSIVARVWNGPVPVRQASVMKTGVIHLAKP
                     GETLSGDAWYSQCTGHRTLCAVVDGLGHGALAAQASQLAVETLRAHAQASLTEQVDLA
                     HRALRPTRGAALGIAEILHDQQLVKFVGIGNIMASICQVGSSRNMVSQNGILGHQIRR
                     VTEFQYPWPESAMLVMCSDGINTHWDINGYAGLAARDPSLIAATLYRDFSRGRDDTTV
                     VVLKKRTADG"
     gene            10051..12228
                     /locus_tag="PK063_06945"
     CDS             10051..12228
                     /locus_tag="PK063_06945"
                     /inference="COORDINATES: protein motif:HMM:NF024970.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ96819.1"
                     /translation="MSYAIINVALKYEDDVVAARQRARQIAGLIGFDAQDQTRIATAV
                     SEIARNAFRYARNGAVEFLIEGQTAPQVLLIRVTDSGPGIADLKLILEGRYQSDTGMG
                     LGIVGAKRLMDQCEIDSAVGKGTRVLLKKVFPSKTRALGAKELSSLVDQLIQTPAQNA
                     QEELRQQNHELLRALDELRLRQDELVRMNQELEDTNRGVVALYAELDEKADHLRRADS
                     MKTRFLSNMSHEFRTPLSSILALSGLLLDRSDGELTAEQDKQVRFVRKAAESLLELVN
                     DLLDLAKIEAGKVDVRPVEFEVKTMFSALRGMLKPLLAGSSVNLHFEEAEDLPTLYTD
                     EGKVSQILRNFISNALKFTERGEIRVTASVDAERRNIAIAVADTGIGIHPADQARIFE
                     EFTQLDSPIQRKVKGTGLGLPLCKKLALLLGGQVTVDSQVGSGSVFTLTMPLYHEKAL
                     DNMLKPGGEAERELDPARLPVLIVEDHPETRLVYEKYLRNSRYQALPSSGLREARRLL
                     YQVRPAAIVLDLLLCGEDSWQWLAHLKSDERTREIPILIVTTVEDRAKAFMLGADAYQ
                     VKPIEAPVLIAELDRLTKKRDHVEPPAPDRPRIMIIDDEESFRYILRKCLSNIDCDVT
                     ESGDGMEGIRMCRELRPDLIFLDLNMPGRSGWQFLQDLAASEKLAGTPVVIVTSQSLS
                     NEARTLLEQSTRGIVMKSELSEEAILHVVGELIPEAFARHHQS"
     gene            12250..>14266
                     /locus_tag="PK063_06950"
     CDS             12250..>14266
                     /locus_tag="PK063_06950"
                     /inference="COORDINATES: protein motif:HMM:NF024583.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ96820.1"
                     /translation="MSTIFQHIILNVDDDEGARYAKTKIFERAGYRVVEAATGADTLR
                     LVQEQQPHLVLLDIGLPDISGIEICRLIKKNPATEHMMVLQVSASCVRPQERAMGLDG
                     GADVYLSEPVEASELIGAAKALLRLYDREQESRVLLKELTERERFIKSMVDAAPSTVY
                     LYDLREQRNLYTNARSGATLGYASDELQFVGRETLQSWIHPDDRPLVMAQLAQLPDQA
                     DGQVLEFECRVQHRSKEWRWFLCRNVVFSRDENGQPLQILGTALDITDRKQQDAILRR
                     GKEQQALLLDISRLILEMPVDRAAWTRAIYEKVAPHLDVDLCLNFLLDQKTKGLQLLV
                     GLGVPDAMLAKAQRLDPGQAFCGYVVDAGTSLVADAELISTDPRGKFVREMGARAYAC
                     HPLKASTGEILGTLSFGTSRKERFTEEEIAFFQTLCHLVALAWERHSVSSALGESEMR
                     LKAIVDSALDGIITIDDQGTIHRVNPAVGRLFGYPADALLGRHITLLLPSLYSVEGAD
                     TPGVDQPRDDSGVSGLRREMLGVRMDRSSFPVELAISENHLDDAVTYTLLLRDITERK
                     KVQEQTRQWTIELEQRVSERTEELLLSRTRLRALASDLTLTEQRERQRLATELHDYLA
                     QLLVFGRMKLSQAKRGNLGPATTLVKELDDMLDEALTYTRSLVAQLSP"
     assembly_gap    14267..14366
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <14367..15341
                     /locus_tag="PK063_06955"
     CDS             <14367..15341
                     /locus_tag="PK063_06955"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ96821.1"
                     /translation="MLDEALTYTRSLVAQLSPPVLREFGLVVAIKWLAEQMRRHEMTV
                     TVQCEADLAPLREDQAVLIFQSARELLINVSKHAKTSQASISVWIENDMLHLCVGDEG
                     VGFDLASTTNIAAPMFGLFSIRERMEALGGRMAVESAPGRGTKITLVVPYVGGSTATD
                     VHSRAGNALASSQVSEPEAVSVLDALAVSPGPQSAHSSRTRVLLVDDHAMLRQGVRTV
                     LEGYPDIEIVGEANNGEQALLLAQSLQPKIVIMDINMPGMDGIEATRRLKLEQPETLV
                     IGLSVHNDWQIEEAMRAAGAVSFLPKDAAIEQLHETIQVAIRAAARTA"
     gene            complement(15372..16598)
                     /locus_tag="PK063_06960"
     CDS             complement(15372..16598)
                     /locus_tag="PK063_06960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HMZ96822.1"
                     /translation="MPSSHSRHKLPSGIWILGFVSLLMDISSEMIHSLLPLFMVTTLG
                     AGTIAVGLVEGLAESLALVVKIFSGTLSDYLGKRKGLALCGYTIGALTKPLFAWAPDI
                     GTLLTARLLDRLGKGIRGAPRDALVADIAPPQLRGAAFGLRQSLDTVGAFLGPLLATG
                     FMLLWADNFRAVFWVAVIPGMLAVALLMVGIQEPVSSSSSRRANPITRANFRRLSPAF
                     WWVVGIGSIFTLARFSEAFLVLRAQQGGIPLAFIPLVMVAMNLVYASSAYPFGKLSDR
                     INHKTMLTWGLLVLIAADVVLATTNHWGVILGGVALWGIHMGMTQGLLAAMVADQAPP
                     DLRGTAYGCFNLASGLAMLMASIVAGFLWDRLGAAFTFYAGALFSSIAVIGIVVSPGT
                     APAPSAGHSLPPRSGE"
     gene            complement(16686..17105)
                     /locus_tag="PK063_06965"
     CDS             complement(16686..17105)
                     /locus_tag="PK063_06965"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96823.1"
                     /translation="MNMKWTHCLPMLLALCLALPTASPAGSPLPAEPGDDFLIEQTFD
                     SVVGLLFRDYSLQGNGQVDYRTARHILGISYDDPASAEPDVALHPLFYWYDRNHDGQW
                     ELWIDREEEGHLVDVTRYDWRQGDDLLTLYPNLRNPT"
     gene            complement(17347..17877)
                     /locus_tag="PK063_06970"
     CDS             complement(17347..17877)
                     /locus_tag="PK063_06970"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96824.1"
                     /translation="MNLRRKTMFLLAGLAALAVTLLLIWCPPALCRVLNIYTFPLSNL
                     SDFRQYVADEEAFYSLHHTRAVRIDCAALRDEVVTVLKIGHLVLETNTPGDTQRERRP
                     GTIEAWHQGRLLHLTNTALASKDEQQAWATSVRAAVTLQQQQDLAFLSRLFGAVVLHV
                     SHRQIPIVLFSDRPCL"
     gene            complement(18051..>18977)
                     /locus_tag="PK063_06975"
     CDS             complement(18051..>18977)
                     /locus_tag="PK063_06975"
                     /inference="COORDINATES: protein motif:HMM:NF024986.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HMZ96825.1"
                     /translation="AFFREALLERAHFEDADLQLADLSGASLLDGYFYGANLSKANLT
                     DADLAGTDLRRTNLRQATLRRANLQGALLDSATLDGTSLVEADLESAYLDDASLVQAD
                     LHEASLRGADFRYARLTNANLQRANLENANIEGANLAKARLNSATMTMSVLYKANLTS
                     ANLHGARLHHAVLIDAHLSRADLQKADLTEVYAPKAHLQQARLAEANLELANLVSADL
                     SEADMSHSIMVQTNLQEANLRGTNLTAADLTGAQLNNADLQQANFRGANLSGALGLVQ
                     AQLDQACLDEATQIPTDLQRPKACPPPRQKRK"
     assembly_gap    18978..19077
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(19254..20588)
                     /locus_tag="PK063_06980"
     CDS             complement(19254..20588)
                     /locus_tag="PK063_06980"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HMZ96826.1"
                     /translation="MTPSTTSLLTDLYELTMTQAYLAHNMTGEAVFEFFVRKLPTRRN
                     FFMAAGLEQVLSFLEQFHFSEGDLAWLEERGRFPPETLIAFRAMRFTGDVHAMPEGTV
                     CFPHEPILRITAPLPQAQLVETRVMNLLNFQTMVASKACRCILAASGKPLIDFGLRRS
                     HGAEAGLLAARASYLAGFAGTSNVLAGAQFAIPTYGTMAHSFVQAHRDETTAFLHIAQ
                     SQPHHVVLLIDTYDTEAAAERVVMLAPELKRQGIAIHGVRLDSGDLGAHARKVRHILD
                     RGGLEETTILASGNLDEERIEALVTSGAPIDRFAVGTAMTTSADAPYLDCAYKLQEYA
                     GRPCRKRSEGKATWPGRKQVYRRLGPDGRLAQDTITVEGDTLPGRPLLRQVMEGGRRL
                     APSPSILEIRDRTRLALSELPDTLGQLDQAEPYEVRISGALERLAQQVDRYT"
     gene            complement(20585..21166)
                     /locus_tag="PK063_06985"
     CDS             complement(20585..21166)
                     /locus_tag="PK063_06985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family protein"
                     /protein_id="HMZ96827.1"
                     /translation="MTNLTSHDALVVVDVQRDFLPGGALGIQDGDKIVPILAGYVAQF
                     HARGLPIFITRDWHPPDHCSFRDQGGPWPVHCIAGSPGSLPPPNFQPPVSAVTIYKAI
                     DQDKEAYSTLQGTPLDRHLRALKVRRLFIGGLATDYCVLNTVKDALGLGYDVCVLMDG
                     IKAVNLHPDDGRNAEEAMLHLGAVPVRLESLAA"
     gene            complement(21217..21600)
                     /locus_tag="PK063_06990"
     CDS             complement(21217..21600)
                     /locus_tag="PK063_06990"
                     /inference="COORDINATES: protein motif:HMM:NF012264.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HMZ96828.1"
                     /translation="MRTFTTLSIRHLILATAAGLMLAPVVDDANAQEFPPDAAKGKAV
                     YERHCLACHGAGGRGDGPDAAGLTVPPANFHRFKSFLKSDEELLRTIEHGVVFSPMHA
                     WQGQLTETERQDALAYIRLLVQQGK"
     gene            complement(21618..21782)
                     /locus_tag="PK063_06995"
     CDS             complement(21618..21782)
                     /locus_tag="PK063_06995"
                     /inference="COORDINATES: protein motif:HMM:TIGR02605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HMZ96829.1"
                     /translation="MPMYDYTCLDCGKESLIVVTLKQHEKGEVQCPACGSTKLQQHFS
                     SFIAHTTKKS"
     gene            complement(21816..24227)
                     /locus_tag="PK063_07000"
     CDS             complement(21816..24227)
                     /locus_tag="PK063_07000"
                     /inference="COORDINATES: protein motif:HMM:NF025038.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ96830.1"
                     /translation="MLDNHRLPASLLAPTVDPARLGFADTSQVQPLEETIGQERAVEA
                     LEFGLQMKSPGFNIFVSGPVGTGKGTLVRQMVQRLAQTAPPPPDWCFVHNFQDASRPS
                     CLSFSAGQGASFKRDMSTFIEGLRRDIPTTFEGKKYLDAKAKIIEETEDKKKNLFHDL
                     TILCHQRGFVFEETAGGFALVPIKDDRPMTGKEMEELPESIQEELTARRQSLESDIRE
                     FHVRMHGLEREAEQALHHLDHQIVANVMKGAYDALLQTYQSSQLVVTYLQRVHDDIVH
                     QYRDFLPHTGPMLAIPGLEQSRRPDLTRFAVNLIVSREAAGGAPVIDESHPTYSNLIG
                     KIERRAHLGVMYTDFTEIRPGSMLQANGGYLILQALDLMRQPFSWEALKRVIKTGAVT
                     IEDPSEFFGFATAGLRPEPIPVSVKVILVGTAGIYHLLQAYEEDFSKLFKVKADFDVE
                     VPHDEHQERQYARFVSRLCREEGLPHFGADAVAEVIRQGFRFADRHDRLSLRFSLVSD
                     LIREAGYWAQKSGHVLVTRADVESALAHQRRRADLPEQWLQGEIAEGTLMVDLQGEVI
                     GQVNGLSVYELGDYCFGRPTRITARTYVGTKGVIDIQREVDLAGEIHSKGVMTLAGFL
                     AGKFAGMQPFALSATLTFEQTYSEVEGDSAAVAELAAVLSSLADLPVRQYLAVTGSVN
                     QLGEIQPIGGVNEKIEGFFESCKRRGLTGKQGVIIPARNIKHLALNREVVAAVEDGRF
                     AVYGVDTADQALELLIGVPAGERGAEGTYPPVSIYGRTAARLEEMAQIVATWGEAEED
                     NRVKD"
     gene            complement(24238..24783)
                     /locus_tag="PK063_07005"
     CDS             complement(24238..24783)
                     /locus_tag="PK063_07005"
                     /inference="COORDINATES: protein motif:HMM:NF014534.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPF/RaiA family ribosome-associated protein"
                     /protein_id="HMZ96831.1"
                     /translation="MNLEVESRNIEMTPRWKTEIEERMAALQRGHDDIIHGRVTLTKN
                     RHHKKLDNVAEALVLVTVPSRQTITSRKEDKTFEEAIRSAFDAVAIELKKFREKRADK
                     VIRVEPLPQRRGVVSKVFPEQGYGFILMDGGGEVYFHKNAVKGMAFADLEDGVEVLFE
                     SEPGEKGLHATIVQPPHLLKL"
     gene            25068..26156
                     /locus_tag="PK063_07010"
     CDS             25068..26156
                     /locus_tag="PK063_07010"
                     /inference="COORDINATES: protein motif:HMM:NF013775.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HMZ96832.1"
                     /translation="MPVLKKSALDGYVKARFGSTAELVAYGPIGKETQGARYKQYGYG
                     APIRLTFRTNGNKTRQVVLGTMSPGPFGHEHPADRAQAMLMDYDCYSRLPRHITALDV
                     GAFTARGELMSVAAAKEFFLLTEWSEGDTYHKDLERLADATRPTPLDRKRTQALADYL
                     ATIHRVKRRDPQLYRRRLRELLGHGECIMGLTDSYPHRYGFITEELLQRIEVACNAWR
                     WRLRRQHARLSQVHGDFHPWNVLFRRGADFSVLDRSRGEWGEPADDVTSMSINYLFFS
                     LCRHGTLKGPLEVLFHSFWDRYLSRSHDQDVLTATGPFFAFRGLVLASPLWYPKLTLT
                     LRRKIFRFIENVLAVPRFDPADVNRYCD"
     gene            26204..26740
                     /locus_tag="PK063_07015"
     CDS             26204..26740
                     /locus_tag="PK063_07015"
                     /EC_number="2.7.1.25"
                     /inference="COORDINATES: protein motif:HMM:NF013730.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyl-sulfate kinase"
                     /protein_id="HMZ96833.1"
                     /translation="MVNMTMAPFALWLTGLPASGKSSIVARLLPKLASMDMTAEVLES
                     DAVRRILTPEASYSKEERDLFYRALGFMGARLLAHGVNVIIDATASRRAYREFARTLI
                     PDLLEVSVECPLHVCMERDKKGTYRRGLQGESSTVPGLQEPYEAPLSPDLVLNTTELL
                     PDAAADQIVRLIRAHRQS"
     gene            26877..28787
                     /locus_tag="PK063_07020"
     CDS             26877..28787
                     /locus_tag="PK063_07020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HMZ96834.1"
                     /translation="MPASLKHIDRDTPMGATLVGGGATFRCWAPHAKAVYVVGDFNHR
                     IRNDAALLTRDQQGHWRGFFPGVKDRQRYMFYVVGEGSEGLKRDPYARELESPFPAEC
                     LIRRTDFPWHESGYVTPPFHEFVIYQLHVGTFFTPNLPHKGGTFLDVARKLPYLADLG
                     VTALQLMPIQEFQTSFSLGYNGTDYFSPEMDFAVADAELPDYVAEVNKLLDAKGLRRY
                     HAADLHGEMNQLKALVDLAHLHGLAVLLDVVYNHAGGEFGDQSLYFFDRQDPAGGQWN
                     SLYFTDRGHAGGLVFDFSKPEVRDFLIQNAKFFLGEYRIDGFRYDQVSVIDHDGAPDG
                     WRFCQDLTSTVHAQRPKTLHHAEYWDVNPFIIAPPPVGAGFDTTLTDGLRIAIRDVIA
                     NASAPDERPLHMTQLAQSLWPQGFSESWRFVQGPENHDIVYNGREARIARLGDPDHPR
                     SWFARSRARVATGLSLTAPGIPMLFMGQEFLEDKQWSDDFVSHRDLLLYWAGLDQGDR
                     QMLDHLRFTRELLALRRLLPALRGRGFRATHMHDQNRVLAFHRWVEGEGQDVMVILHL
                     ANFTRVGYQIGLPGEGAWREVFNSDVYENWVNAGVAGNNGRVLANPQPLHGFGYSAGL
                     VLPANSILIFAR"
     gene            29023..29346
                     /locus_tag="PK063_07025"
     CDS             29023..29346
                     /locus_tag="PK063_07025"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96835.1"
                     /translation="MMTRKILATLMFVWGIGLVSLAQAFQTAVVFPVSSVEHVDSRNQ
                     VLTFKTQDGQVRMFRVAQSVGMKRESLAKGDLVRIEVDLDDQIVNIVKLTQTSLSDRE
                     ALRRK"
     gene            complement(29400..30215)
                     /locus_tag="PK063_07030"
     CDS             complement(29400..30215)
                     /locus_tag="PK063_07030"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96836.1"
                     /translation="MATTPDISRAWPPDDHYSLLQRCRSLYHELWFRLSERIRWSRQP
                     YHEKPIGCLAGLTSWQIARINELQVRYDLRFETHYGQHTALANYAYLDLLHQAWTDTN
                     RPVPQGGVVADVGCANFWYARTLHAFFRPATLTGVDVEGFRLYPTGYSRYDAARGYIA
                     GLSQTSFLVANYCEVETKADVITAWFPFVTPSPVLAWRLPLTVFSPERLFDRIARNLT
                     SQGLFFMVNQGSDEAAIAADYGRRAGLRLVDRWVHPRPLRTRPHPPVVTWWTT"
     gene            complement(30306..30761)
                     /locus_tag="PK063_07035"
     CDS             complement(30306..30761)
                     /locus_tag="PK063_07035"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HMZ96837.1"
                     /translation="MTQAGEPIRVELVDWVHAEQLIRPIRETVFIREQAVPEELEWDG
                     LDPQCVHVLAWNKQGDAIGTARMQAQGTIGRMAVLKDWRGRGAGRALLEALLECAVRQ
                     GLTRVTLSAQTHAIGFYERAGFHVIGELFMDAGIPHRRMVKELIRQESE"
     gene            30989..31249
                     /locus_tag="PK063_07040"
     CDS             30989..31249
                     /locus_tag="PK063_07040"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96838.1"
                     /translation="MNIQQRRARVGSLRKTRAGMWRAWCHAGAKEARPSVFSWDFLRS
                     VWSLLCRMTRNKGVRPDENRFAWQEHIGCTAPRSSGIYGRMI"
     gene            31527..32381
                     /locus_tag="PK063_07045"
     CDS             31527..32381
                     /locus_tag="PK063_07045"
                     /inference="COORDINATES: protein motif:HMM:NF012791.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HMZ96839.1"
                     /translation="MKVLIATDGSKYGKWATEWVARMPFAEKPEVALLHVTDVEALRA
                     PFMFQPVVIGNEPFIQEEIKRIEARGKTAITEAKAQMASLKLKGKVQSERGPAGPTIL
                     DRAPRRDGIVAIGSRGLDALDRFMLGSVSTQVTLHAPCSVLIVKEEPRPVSRILFAAD
                     GSKASEKALRFLLTKLQPEAREGFEPIDVVVMHAMPFLKYPELKEAGARLVEQCANKL
                     IKAGYVVDEVVQLGKPADEILKVASKKKVDLIVTGAKGMGAVARFLLGSVSTKVVQHS
                     TCSVLVVR"
     gene            32527..33804
                     /locus_tag="PK063_07050"
     CDS             32527..33804
                     /locus_tag="PK063_07050"
                     /inference="COORDINATES: protein motif:HMM:NF012739.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HMZ96840.1"
                     /translation="MWLYTAGTCRTDNGHMTDRVAALTCEFRRLLPRPACSLHLAGRA
                     LLVVLLMGQVGCDRDPGVPPAAKPVSRAADGIVQLTAAEIGRAGIQVQRAAKEPFVLH
                     REFPATVQANENELAEVTTLIRGRVVDVLVDAGKDVKKGERLALLDSTDLGMAEGVYL
                     KATARQHEAQLAHERAANLHEHRAISLAELQRREAEMKTAQAEAREAGHRLRLLGVPD
                     QEIQRLERERTIRSDIAIRAPFAGRVIMRNLTRGEVVETSRNCFTIADLSDVWVIASV
                     PEKDVQFIHPNQTVHVIVAAYPHSLFSGRMTYISDVLDPTTRTMRIRVTVPNPDRALK
                     PEMFAMVRVDASPQPAVLTVPLSAIQQEGGGKMLFVRQGENRFAPRRVQLGDEQDGQV
                     IVLEGLREGEDVVVKGAFAIKSELDIHKIEPTQ"
     gene            33801..36929
                     /locus_tag="PK063_07055"
     CDS             33801..36929
                     /locus_tag="PK063_07055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051139 - metal cation:proton antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CusA/CzcA family heavy metal efflux RND
                     transporter"
                     /protein_id="HMZ96841.1"
                     /translation="MIAALLEFSLRQRILILGLACFCAAAGVFAFQSIPIDAYPDVTN
                     VQVQVLTEAAGLSPVEVERFITYPIELQMNGLPGLTEIRSISKFALSQLTVVFEDDVD
                     VYFARQLVLERIMAVRERLPAGMEPVLAPVTTGLGEIYQYYLEGGTKPDTNAALVEEA
                     LTNQRTIQDWVLRPLLKGVPGVIDVNSLGGFVKQYQVLVDPDRLRKYSLTLHDVFDAV
                     ERNNANAGGNVLERHAERAIVRGLGLIKSLADIERIVVKEAGGVPVFVRDVAEVRIGH
                     AVRHGAAVLNGEREVVAGTVLMLRGGNAREVVQAVKQRAESIERQGILPGGLTLVPFY
                     DRIELVTAAIHTVRDALIEGVVLVALVFFLFLGHVRSAIVVTVSLLVTPLITFVVMQR
                     VGLSANLMTLGGLAIGIGEIADGSLVVVENIYRHLSENRLQERSRLEVVLRATNEVGR
                     PILFGILIISVVFLPLMTLHGMEGKMFAPLAYTLVISLLASVIVTLTLSPVLASLILH
                     GDHPEETRLTRWMKAQYQPVLRWTLDHRAAVLLSSTAIVLASLSLLPSVGREFIPILE
                     EGALTPQIVRLPSVSLDESIAIEKQTQKVMLEFPEVRMSVSKIGRPDIAVGPEEPNES
                     DPIVALRPREAWITAQTQAKLVDAIRTRLAEIPGISVLMSQPIQERVDELISGIRTEC
                     AIKLFGDDLDLLYQHAERIADLMRTIDGVKDVKVEQVAGQPYLTIDINREKIARYGIN
                     VSDVQDIISTAVGGRPATQVYEGERRFQLVLRFPESSRNSIGAIGDIRVRSASGAPIP
                     LSELAAIEMREGPARISREQAKRRIYIGFNVVGRDIGGVVDEGRKRLAEQLRLPQGYT
                     VAWGGAFENMERANARLLVVVPITLGLVFFLLFWAFHSLRYAGLIILNLPFALIGGVV
                     SLWLSDQYLSVPASIGFIELFGLAVGNGIVLVSYINQLRNEGQQTEAAIISGCVLRLR
                     PVVMTMMTTLLGLLPLVLAQGIGAEVQRPLATVVIGGLFTSTALTLLVLPALYRTFAE
                     QDVTKEHAPEWV"
     gene            36950..39475
                     /gene="mgtA"
                     /locus_tag="PK063_07060"
     CDS             36950..39475
                     /gene="mgtA"
                     /locus_tag="PK063_07060"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HMZ96842.1"
                     /translation="MLKQTPFWSLSADDVLRQLSATPNGLATAEVDARQATSASVRLK
                     PQRNSRPLRLLMAQFRSPIILILLFASGVSFFLAEHSDALIILTIILVSALLSFWQEY
                     SAARAVAGLLALVQITARAWRDGELRDIPADHIVPGDVIELSAGSSLPGDALVLEAKD
                     LFVDEATLTGETYPVEKSVGSLPAHAPLAKRTNSLFLGTHVVSGQARVVVVAVGTDTE
                     FGRIAHRMALRAPETEFERGVRRFGYLLLEVTLLLVLAIFAVNVYLERPALESFLFSM
                     ALAVGLTPQLLPAIISVNLSHGAKRMAQQNVVVKRLASIENFGSMNVLCSDKTGTLTE
                     GSMRLHAALDLDGQPSERVLFHAHMNAMFETGFPNPLDEALRQHRSFDLGSYRKLEEE
                     PYDFVRKRLSVLVATPQTHLLITKGAVESMLSVCLHAEQQNGSLMPMDQVRASIREQV
                     RGLSSEGYRTIGVAYRDLGAIDRVSKEHETGMTFLGLLVFVDPPKAGIVDTIALLRKL
                     GVSLKMVTGDQGLVAAHVGRQVGLANPRLLTGSDLRGMTDDALRARANEVDIFAEIEP
                     NQKERIIRALRGSGNVVGYLGDGINDAPALHAADVGLSVDGAVDVAKEAADLVLLEHD
                     LSVLVEGVREGRRTFANTLKYVFMATSANFGNMFSMAGASLFLPFLPLLPKQILLTNV
                     LTDIPEMTIATDHVDSELLDRPRRWDIPFIRRFMLTFGLVSSFFDYLTFGILLFLLHA
                     TTAQFRTGWFVESVLSASLIVLVIRTRRPCVTSRPSAPLLWSTLLIALVTILLPITPM
                     GSFLGFEPLPAVFWVALLGILLAYVAAAELAKTFFYRQVNNGR"
     gene            39625..41142
                     /locus_tag="PK063_07065"
     CDS             39625..41142
                     /locus_tag="PK063_07065"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ96843.1"
                     /translation="MPGSPHSPNGLSYDPQVLLNSQPVIVTVIDPADHSVQFQNQTGL
                     GAFGDMAGSPCYEKIAGKTAPCEFCRMPEALSRDGVVSEQVEMPNGRHLLVHWAKAPT
                     KDGRVHVIETIIDLTKRKQDEQSLRQSQKMEALGRLAAGIAHDFNNLLMVVIGHAHRV
                     AQQLGSHPLHHEVEMIGQAGTRAAALTKKLLTFSRRQVLEQRDVPLNTLIRDMEDILR
                     RLIGEQIQTVIVLHPQAGHVLGDPVQMEQVLLNLALNARDAMAEGGILTIETGNTDVD
                     EQYVRTHPGAVPGPYVTLVVEDTGCGIDAETLAHIFEPFFTTKEFEKGTGLGLATVYG
                     IVKESRGYIDVTSQPGRGTRFTVMLPRVQSQTSEAEQPASSRPLPATCATILLVEDDE
                     GIRRLVAAVLRDQGYEVLAAADGVEALQMLQLRKGGCDLLITDVILPRMKASVLAQGA
                     RTMFPKIKVLYISGYAGDMLVSHGVDAQAAYLQKPFMPQAIIEKVAELIPPAPAQ"
     gene            complement(41346..41714)
                     /locus_tag="PK063_07070"
     CDS             complement(41346..41714)
                     /locus_tag="PK063_07070"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ96844.1"
                     /translation="MSKRKNTRVEMNRPIDVQGPRGTSQGVVKDFSPGGCKIQQTAAK
                     VHCGMRLTLRISLPDRIEPIEIKPAVVTWTSKDAFGVEFLALSAETRSRVKLVYDLLL
                     DAQSTAETERVISLPGVSWK"
     gene            complement(41763..42752)
                     /locus_tag="PK063_07075"
     CDS             complement(41763..42752)
                     /locus_tag="PK063_07075"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96845.1"
                     /translation="MPSAMKQLLASALGYALMASGAGLAEEIPHQRSIALIDKTWAVS
                     LDMTGYRVQADGVKPDSRRYVLATNDAAAMQLSVTLEAVSGQATEQGCLAHLHRIAQT
                     AAAPSHAGPTRTEINQLPVFEYLLYETSAGWTDQVHLFACTNKDNVYTDIHLSHSGTT
                     TVDASQLRKVLESLSIVAAAQPGSLDYFRAGSAPYLQGQFKQAIPHYERAVALERTNP
                     SLDKALWRLLVHNLGVAYRRSGDLARAKTTIDYGLSQEPANPSFHYDLARTYAGMNER
                     DRAMQSLHDAFLHFRRSNDREPIPDPRQDVSFGRFMLDPAFRTLTESLMQPAI"
     gene            43096..43710
                     /locus_tag="PK063_07080"
     CDS             43096..43710
                     /locus_tag="PK063_07080"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96846.1"
                     /translation="MRERDVQAIGTRRGARVGWPTVFGICAVAMMAQVSSAPAVVHVL
                     PDMTVTRDSGTVTGAKAVRADPTLQEVLAAFDRAERALEKQDLSSLMQFYAPGYNYHG
                     LHVEDVQRIWGEVFEHYRTLSSTHLFSEMKIVRAEDGLRVELTCTGGLYGADVQSGAR
                     ITLDSWFQEVHYLVRDRQGWRFLGNRGDAPRSAPFSSSPHHPLF"
     gene            complement(43729..44181)
                     /locus_tag="PK063_07085"
     CDS             complement(43729..44181)
                     /locus_tag="PK063_07085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96847.1"
                     /translation="MTRSSWSSSNPLPDNLRASLKDLRHGLLGLHKSLIVSEQLTYER
                     IYGRISSAGQLLQLVMNDPWFAWLHPLSHLVVRIDVVLEDHEDTTIETAQDLLLEARH
                     MLRPSEEGDGFERSYYEALQRTPDVVLAHASVKKLLSTAATAASAAAA"
     gene            44474..>44787
                     /locus_tag="PK063_07090"
     CDS             44474..>44787
                     /locus_tag="PK063_07090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-transporting P-type ATPase"
                     /protein_id="HMZ96848.1"
                     /translation="MVEARQHSQTRWYARSLDDLGREFGVDQALGLDEDEAARRLTAH
                     GPNELPEAAPPSPWHMLGAQFSSLIIWVLIGAALVSGLLGEWVDACAILAIVLLNGLL
                     GFV"
     assembly_gap    44788..44887
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <44888..46978
                     /locus_tag="PK063_07095"
     CDS             <44888..46978
                     /locus_tag="PK063_07095"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HMZ96849.1"
                     /translation="GKGRALIVATGSGTELGRIATLMTTVPVEPTPLQRRLEQFGHVL
                     LWLSLAIVVVVFGLGLWRGEPLFEMFLTAVSLAVAAIPEGLPAIVTTTLALGVMRMVS
                     RHALIRRLPAVETLGAATVICTDKTGTLTKNEMTVTRLAVDDVVYDVTGEGYAPEGTI
                     VDGDGRTGALRALLWSAVLCNGSSLRAAEGSWTVVGDPTEGALLVAGGKGGWRKEALE
                     RAHPLVGEIPFDSERKMMTMIRRSEGRAVAYVKGAPDILLERCDSYMTKSGEVAPLSD
                     SMRRSMVSINQQFAQQALRVVALAQRVLDPDPATFESKGIEQQLVFLGLAAMKDPLRP
                     EAKQAVERCRSAGITTVMITGDHKETALAIGREAGFASGSTQALSGLELNGLTDAELS
                     SRVRDVCVYARVSAEHKLRIVRAWRAQGAVVAMTGDGVNDAPAVREADIGIAMGMTGT
                     DVTKDASDMVVTDDNFASIAAAVEEGRSIYENIRKAVHYLLSCNLSEVLVMLGSTLLG
                     WPLPLLPIHILWINLVTDGFPALALAVDPKDPDVMKRPPRDPKAPLLDRQRFVTVCVQ
                     GAVMAAATLAVFGIALVIMKDEVTFARTMTFTTLVLVQFLHAFTCRHDRFSLFQIGIT
                     TNRMLVAAVLISALLQAGILLSPWGQDIFRVVPLRLDDWWLVAACGMLPFVVMELWKA
                     WSRVRNGAARTSTA"
     gene            complement(46968..47840)
                     /locus_tag="PK063_07100"
     CDS             complement(46968..47840)
                     /locus_tag="PK063_07100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HMZ96850.1"
                     /translation="MNRSVFALVFTALFLSWTTPGSAHSPLPKPDHVVIVIEENHAFG
                     QIIDSPAAPYLNALARKGALLTNSYAVTHPSQPNYIALFAGTIEGVNGNVCPTPLTAP
                     NLSSTLKQAGQSFIGYSEDLPAVGAVDCIAGAYARKHNPWVNWQASPVNTVPAAQNRP
                     LTDFPTDLSTLPTVSIIVPNQQNDMHDGNDPDRIQRGDHWLQVRLERYVDWAQTHNSL
                     LIITWDEDNGKSDNHIPTILVGPMVRPGRYHEQTNHYGLLRTITDMYGAQPVGLSRQA
                     SPLTTIWAAPKLTP"
     gene            complement(47858..49588)
                     /locus_tag="PK063_07105"
     CDS             complement(47858..49588)
                     /locus_tag="PK063_07105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ96851.1"
                     /translation="MFSFKRFYPFLKPYVPRMIAAAVMVMAVAAINLALLRLGGTLWD
                     VITVQHDAPRMTNMILLLLGLVLIQGLCSMGHSYLTAWVSQRVMADFRIHLFAHLETL
                     SVNFFSKRRTGELMSRLMNDVTVIQNVVTDTPIDAAKQIVTFIGGAGFLFAMNWQLCL
                     LILVLLPMLVVVAKLFGRRLRALSTKIQDQTATVSTLVEEVIAGIRVVKSFVQTKREE
                     ERFVTQVQSAMELSLRRATIMAWFVPTIIFVTFAAAALVLWYGGRQVIDGSVSPGDLF
                     AFVLFAGILIGPFGSAARVFAQIKEAQGAMQRVFEILDTHAEIADAPGAIELPAVRGH
                     VRAENLSFAYDPRQPVLSDVSFEAKPGELIAIVGPTGSGKTTIMNLLHRFYDPTSGRL
                     TIDGHDVKNVRLDSLYRQIALVPQDTILFGGPIRDNIRYGREDATEEEIIAASTAAHA
                     HEFIVGFPDGYQTIVGEKGINLSGGQRQRVAIARAILKNPRILLLDEATSALDTESER
                     LVQEALERLMVNRTTFVVAHRLSTIQRADRILVLNKGKIVESGTHAALLEQQGLYHYL
                     YTLRLSELPV"
BASE COUNT         9785 a        13912 c        15597 g        10261 t
ORIGIN      
        1 acagcaatcc aagcctggct atcatggcca gacccagccc cactcggcgg gcgacggcgc
       61 gttgagattc cgggagccgg ctgaccagaa ccgacaggaa gatgatgtta tcgatcccca
      121 gcacaatctc aagcgcggtg agggttccga gggcgatcca gatttccgga ttggcaagcc
      181 attccaacat cagcgactcc attcatctca gggaacgagt gactcgatcg gtcatgcgag
      241 aaggtgtggg aacaacacgt atgaggagag tctaccgttc ggacgtggtg ggcgcaatca
      301 aaacgtgggt ccaatcgaaa ctcggccgcg aggctcgtac ccctcgcggc cgagtcaatc
      361 agcttcgtct gaggaaatcc ggccggtccc ggatcgcaac catcttcacc aggtctctga
      421 tagagaggac cccgacgatc ttctcatgct cggtcacagc caagtgacga atgcgtttag
      481 ccgccatccg ttcactggca tcgcggattg tgcggttgat gtcgatgtcg agtaagggcg
      541 agttcatgag ggcgcccact cgcatggctt cgggatcgag ctgataggcg agcaacttcc
      601 gcacgaggtc accttcggtg atgataccca cgagttcgtc cgcttcgatt acaaagagcg
      661 ccccgatgtg tttgtcggcc atccgttgtg cggcggccat ggcggtttct tcgctgccga
      721 tggtttcaat cgccttttgc atgagcacgc tcagcgggcg atagacgttg gtcagtgcct
      781 gtaccggccc gccgtcggca tctacgaaat gtcgcacgag atcacggacg gaaatgacgc
      841 cgagcacgtc cgtcccttcg gtcacgacca gatgccgcac gttcttgcct tgcatgagat
      901 ggctggcatc gaccatcggt cgatccggtg caatcgtgat gagtgggctg ctcatgatgt
      961 cagccatgct ggttcgagac ggaacccggc cggcggccaa gactttggag acgagatcgg
     1021 tttcggtcac gatgccggca atccggcaat cgttgtgagg gcggtcgaag gattcgatca
     1081 acaccgagcc gatgctgcgt gtccgcattc tcgtggcgac ggtcaccacc gaggtatcct
     1141 gcggaaccac ttccaactgc cggtgcatgt aatcactgac gtgcgaacca tgtgcggtcg
     1201 tcatacgaac gtcctttcgt ggagagtcgt cctgtggcgg cactgtgcaa ccggtgccga
     1261 tggtcgttca atcagcggga attgttcatg gctcagtccc ttcatcatcc agcctgccgg
     1321 gttcgcatgc gcccgctcag agatttcttg aacccatcgg ccagcagaag tccgatggct
     1381 cccaagacca acggcccata gatccaggcg gggatggagg ctgtgccgag gatcagatgt
     1441 ccgagcggac tgtaggtcat gatgaacagg agggtcagtt caacagccac tcccaacagg
     1501 agcaatggat tgctgaccca accgagttgg aaggccggga agcggtccga ccggcaggcg
     1561 aaaacgtttg ccacctgggc cgcgacgatc ccggcgaagg tgacggttgt tgcttccttg
     1621 tacagggggg agttccagtc caatggatca ccccaggtcc agccctcgct gtggaggtaa
     1681 aggaagaagc cgcccatggc gatgccggct tcgatcaggc ctagaaaagc ataggcccgt
     1741 atgagtacgt cccggttgag gaggcgctct gtccttggtc gcgggggttc atccatcacg
     1801 ccgctgtgag gccgttccgc agccagtgcc aaggcgggca ccatgtctgt tccaagatcg
     1861 accgcgagaa tttgcggaac ggtcaacgcc agcggaagcg acgagagtcc gtacgccagg
     1921 tagggcacga cctcgggaac gttgctggcc aacacgtagg tcatgaattt gcggatgttg
     1981 agaaacacgg cccggccctc ttcgatggcg ctgacgatgg tggcaaaatt gtcgtccagc
     2041 aaaatcatcg aggcggtctc cttcgccacg tcggttccgg ctgcccccat ggcaatcccg
     2101 atgtctgcca tcttcagcgc cggcgcatca ttcacgccgt cgccggtcac tgccaccact
     2161 tcgcgcatct ccttcagcac ggacacaatg cgcatcttat gccggggcgc catgcgggcg
     2221 aagatggggt ccggttcgcc gggagctgtt ggcgtgagaa ggcggcggag ttgctcatcg
     2281 ctgaaggtgt ccacctgtgc gccttcaatc accggcacga atcgccccgg ctgcgcgacg
     2341 ggagtctccg gcgccaggcc gattttgctc gcgatggcct gagcggtcat cggatgatcg
     2401 ccggtaatca tcacgacgcg gatcccggcc tttcggcatt tctggatggc gtccggcacc
     2461 tcgcggtgtg gcgggtccat catggcgacg agtccgagga acgtcaggcc ctgttcgagg
     2521 gtatcggctt ccagttcatc aacgccgcgt tccacttcac gcatggccaa ggcgagcacg
     2581 cggtacgctt gccgcgcgaa ggtctggctc tgtgccagaa tctttttccg tccgtcgggg
     2641 gtgagttccg cggcggctga ggatccctgc tgcatggtgc atcgcgggag gactgattcc
     2701 ggcgcgcctt tggtgaacgc gagtaagcgg ccctcgctcc agtgcagggt cgtcatccgc
     2761 ttgcgatcgg catcgaaggg ccattcaccc atgcgccgca gcgggggccg atgaagcaac
     2821 ccatggtctg cggcaaactc caggagcgcc gtttctgtcg gatccccggt ggcctggctc
     2881 cgcccatccg ggcggcgcgt ccgtttggca ttgttgcaat ggatcatggc gtcgaacagc
     2941 ggacgccacc gttcggattc agcggcgctg ataaggcggt ttcgcgagaa caagcagctc
     3001 tcccgtgatt cgacaatgag atcgtcgaca taaagtttgt cgaggcgcat acgattttcg
     3061 gtcaacgtgc cggtcttgtc cgtacagatg acagtggtgc agccaagtgt ttcgacggag
     3121 gcgaggtgtt tgatgagggc tttgcgcgcg gccatccgct ggctgcccat ggccagggcc
     3181 agggtgacgg tcggcaggag tccttcaggg acgttggcga cgatgatgcc gatgccgaac
     3241 atcgcgctgc tcaaaaatcc cagacccatg ctgacgccga tggcaaaaaa cacgaggccc
     3301 atggcgacgg acaggccggc cacgacgtgc gtcaccttca cgatttcctg ctggagcggg
     3361 ctgagcccgg attggacgga cgtcgtcaaa tgcgcaatct tgccgaattc agtgctgagg
     3421 ccggtcgcaa agacgacggc ctggccatgg cctgaaagaa cggttgtccc cgcaaacgcc
     3481 aaattcgcaa tgtcgagcgg gtggccatcg gtgatgggct cagccgtccg ccgttgcggt
     3541 ttcgattcac cggtgaggga cgagttgtcc atccgcattc cgctgacctc ggtgagccgc
     3601 gcatcggcgg gcacctgttc gccttcctcc agcacgagca catcgccggg tacgagttcg
     3661 ctgcgggcga tctgttgctg ttggccgtcg cgaatcaccc aggctttggc gggcaacatg
     3721 ccgcgcaagg cctgaacggc ccgctccgct cgatattcct ggaagaaggc gaagatggcg
     3781 ttgatgagaa tcacgccgag gatggcccga cccagggtgg ccataccctc cccggcgtgg
     3841 aaggcgtcgg caagaaaggc gaggccggcg gccacccaca acagcagcgc gaggaaatgc
     3901 gtgaattggc gcgcaaaccg gccgatgagc ggcgtgcggc gcaaggcctg caggctattc
     3961 ggcccatgct tgagagttcg tcgccgcaca tcatccgcgg agaggccttg cggcgaggtg
     4021 gccaatgcac gaaacacctg gctcggcgcc aggcggcaga tttctagcgc cgtcagttca
     4081 ggcacgccac cctcgcacga tgaggaccga gcaaggcgcg tacttcagga gcgtttccga
     4141 tacgcttccc agctgcagcc gttccgaccc cgtcagtccc cgcgagccgg caacgagcag
     4201 gtcgatggag cgcgaggtcg cctgccggag gagcgcatca gtcacatgat caaactgcac
     4261 ctccggcgtg accgcatacc cttcggccag aaaccgggcg cgcaacttct ccaccagctg
     4321 ctcagccgct tgtcgcttgg gcgcggaaat ttgctctacc tggtcgcgtg acaggtactt
     4381 actcgccagt tcggtgacgg cgggctcgac cacggaaagg accgtgaccc gggcggaatc
     4441 cgggaggaat tgtttacaca ggaagctgca ggcgccttgc gaatgttttg acgtatctgc
     4501 cgcaacgagc acgtgggaga ggctggtgag aggccgtttc acgacgagca ccgggcaggg
     4561 cgccagtgcg ctgactttgc gcgagacact gcccagcagg taatgctctg catcgctgag
     4621 gccgcgcgag cccaccacga gcaggtcggc ttttttctgc ttggccacct tcgcgatcgt
     4681 gtccgccacg cggccatggg cgagcagcgt gtcgatggtg gtgcgaggtt tggtggtggc
     4741 ctgcttcagt gcggttttcg ccaggccttc gaagcggcgc agcacctgat cgccggcttt
     4801 cgtcattgcg gcgatggcct gctttgagac agccgcgtgt ttgcgggctg aggacttcag
     4861 cgacgcgctg tcgacgacat gcagcaaggt cacggtatcc ggcgggcgtc cggcgatcgc
     4921 ttccagcatt tgcacgctcc attcggcgaa ttccgatccg tctaccgcaa ttaacatgtt
     4981 catcgctgca ttcctccatg gcctgactct atcctggaat gtagtctgca tcggatatgc
     5041 ctgaacgaga tcaaactcta gcaagccatt ccatacgctg tcgaacggtg agcggccttg
     5101 gcctcgtctc ggggatcgtg ccgcgatcgt ggcgctgcgg cgttttgcag cagtgtgggg
     5161 tgtcagtttg gggtaattgg cctcagttca agggtttgcg gtgggctgac ggtgtgatct
     5221 gatgcggcct cgtaagcgat ttctgttcga acacagggcg ccgtactcag gcatcaccat
     5281 tgcgtgacaa tcgagtagga ggaaccgaca tggtgaagac gtacctcatg gcattggtcg
     5341 gcgggtgtat ggtcatgagc ctcgcgctga cggcggatgc gagcgccggt ggctcgacgg
     5401 tggtcgctca tgtgctttcc gacgaggagg ccgtcgaact tgagatcccg acggacatcg
     5461 gtgtgcagaa agaacgtctt cccctgtatc gcctgggcgc agtccggtac ttcagtgccg
     5521 ggatcgggca ggtcgagcgg acagccagtt atccgctctt ttcgttgaag cttgtcttca
     5581 cggcgggggg gaagcccttc gtctcggggg tagccgtgac gctccgtcag cccaaagacg
     5641 gaacggtgtt gacgattcca ggtgagcaca acacaggccc gtggttgttt atcgacctgc
     5701 ctgacggcac gtaccagata tcggccacgt tgggcggcgt cacgcagcag gtcaacaatc
     5761 tcaccgtgcg gcgaggtcat gtcatcacgc agcatgtccg ctgggccgag gaccggagcc
     5821 ctgcattgcc tgcgcaagct gagtagcaat gaaggtcaca atacatgggt cgatcaggag
     5881 gaggaagcat ggtgacgaaa cgcaaggccc tggcgaaacg atcggcgagc gcaggccgca
     5941 aaccagtacg gttcgaggac ctgacggtga aagacattgt gaaccagcgc gtccagtcgg
     6001 ctcgccttga tctcaccggc atgaaggtag cgtcgttgct actaaaagca gggggcaccg
     6061 tgccggttat cgacacatcg aaacaactgt tgggcgtggt gagtgaacat gatgtcctgc
     6121 tggcccttga cgaggggcag gcgtggggca ctcgaacggt tcgggatctg atgagcgcga
     6181 atccctattc ggtgcggcct gagaccagtt tgcccacgct ggcccatgtg ctgacggaaa
     6241 gcgacctcct tgcggtgccg gtggtaaatg acaagaaccg gcttctgggc atggtcacgc
     6301 gccgggatgt ggtacgagcg gcattgcggc ccgccgcgaa acgacgatct gcagcggggt
     6361 agccggatcc gctgtccgat cgtaaaggag catgtatgcg ccgaatcgat ctgctgacgc
     6421 aggcttgtga tcccgccacg ctgacggtgg gacaactgat gcaggatgcc ttgtttacct
     6481 gcacgcctcg tacggatgcg ctcaccatcg gccgcctcat gacgaagcag aatttcggtg
     6541 gattgcccgt gatcggggaa cacggcgacc tggtcggtct cgtgacggaa tacgatctgc
     6601 tgcaggcgat gatcgaaggc cgggatttgc gcaaggtctt ggcagccgac atcatgacca
     6661 cccatccatt gaccgctcgc gaggacatgc gattggaaga agtcgctaat ctctttcaag
     6721 atcgctacgt gacgcgtctg ccggttgtgc ggggagcgct gcttgttggt atcgtcgcga
     6781 gacgggacct gttacatgga tatatgaagg cgtcggaata ctggtcgtaa ccggatggga
     6841 tagattctct tttcctgtcc catctggagg ggcgaagtgc cgccgaccgt atccattctc
     6901 ctgctctaca ccttcgaaca ccgtacctca ccaagattca aaagcgcgtt gcgcctgggc
     6961 catagcaggc atgaatgaac gaacagtctg caggagttcc ccaacggtcc atgggtagtt
     7021 atccaaggcg cggcatcgac atcccaccgt tgattcggct cactttctcc tgctcatagg
     7081 cccccgcagc cgctcccggg cggcgaaaaa cccccttgtt gttccctctg gaagtccaaa
     7141 acgattttcg ataggctgtg ccgaattgcc aggggttttc ctagtgggag atagaccagc
     7201 ggggcgcata cagttacccg cccccgtttg tcattccaga tgaagtcccg ccgtaattgc
     7261 atgggtacaa tttgatgtga gaggaggctg gaagggcatg gagaagcgaa cgaaactggc
     7321 ggaaatagtc aggaatcaac aagacaccat tctcaaagac tgggtggatt ttcaattgaa
     7381 cgccatcacc gtgcgacgtg atctcatgaa ggacagtgag ttgcgggaac agtcgcggga
     7441 attcttgaac ctcttcaccc aggcggcgca gaccggatcg gatgtcagtg aagctatctg
     7501 gaagcccgtc aaagacttcc tggggcagat taccaggtct cgcgttctgc tgggctttac
     7561 tccctccgag accgccacat ttattttttc tctgaagcaa ccgctgttcg atgtgatccg
     7621 tgccgccgtc aaggacccga aagatctcgt ctcagatatg tggaccacga cgaccctcct
     7681 cgacaagctc gggttatacg tgatggaact gcatcaacag aaccgggaag aggtcattca
     7741 tcgccagcag gaggagctgt tggagttgtc gacgcccgtc gtccagttgt ttgagaacat
     7801 cctcgccctg ccgctgatcg gtaccttgga cagcgcacgg acccaggtcg tcatggagaa
     7861 cctgttgcaa cggatcgttg aaaccggcgc gacgatctcc atcatcgaca ttaccggcgt
     7921 cccgaccgtc gatacattag tggcgcaaca tctgttgaaa accgtcgcgg cggccaggct
     7981 catgggtgcg gattgcatca tcagtggcat tcgtccgcaa attgcccaaa cgatcgtgca
     8041 tctgggtgtc gacctcagcg aagtgacgac caaagccacg ctcgccgatg cctttatgat
     8101 tgccttgcag cgcaccgggg ctactgtgac gaagtctgct gcgaccaggt cgaaaggata
     8161 accatggaga ggatcccgat tttaaaaatg gggaatttcc tcctggtcac cgtccaggtg
     8221 gacatgcacg atcgcctcgc catgacgtta caggatgatt tgaccggtcg aatcgtcaaa
     8281 gaccgcgctc acggagtcct catcgacatt tcgtcgcttg agatcgtgga ttcgtttatt
     8341 ggtcgcatga tcggcaacat cgccagcatg gcgcgggtct tggacgcgga gacggtagtc
     8401 gtcggcatgc gtccggctgt cgccattacg ctggtcgagt tagggctgtc gctccccggt
     8461 gtgcgcaccg cgctcaatgt cgatcagggc gtggaactgc tgaaagagtc cattgaagag
     8521 agagctcaag ggaatggcca cgttgcggga tgagatctat cccatccgct cttcggacga
     8581 catcgtgaag gtccgtcaaa tcacgaggga atgggcgctg atgcagacct tctccctcgt
     8641 cgatcagacg aagatcgtga cggccgccag tgagctcgcg cgcaatacgc tcgagcatgg
     8701 ccgtggcggc gaggtgcgta ttcaagcgct gcaggaaggc ccccgccggg ggctccgact
     8761 cacgtttacc gaccaggggc cgggaattcc cgatcttgcc aaggccttgc aggatggata
     8821 cacgacggga aacggcatgg gattgggcct gagtggctcg aagcgcctca tgaacgactt
     8881 cgatatccaa actgaggtcg gtaaggggac aacagtcatg attgcgcgtt ggaagtgaga
     8941 gcgatgatca aggaacaaca gatggcgggc gatcaggtgc aggtgccggt gggcgaatcc
     9001 acccgggtcg ccgaggcgcg ccgcaaggcg gtcgaattgg ccggacggat cgggttggac
     9061 gaaacgaaga cagggacctg cgcggtgatc gcgtctgaga tgggcacgaa cctcgtcaag
     9121 catgcgacag acggggaaat gtttgtgcgg agcgtgacgc aggggacgat gcagggcatt
     9181 gagctcgtgg cgatcgaccg aggccccggg atgtcgaatg tgagtcacgc attacaagac
     9241 gggacgtcta cggccggaag cagcgggaac ggtttaggcg ccatgatgcg gatggccgcc
     9301 gaattcgaca ttcattccct gcccgggcgg gggacgagca tcgtggcccg cgtctggaat
     9361 ggaccggtgc cagttcgcca ggcctcagtc atgaagacgg gcgtcattca cctagccaag
     9421 ccgggcgaga ctctttccgg tgatgcctgg tattcccagt gcacgggaca tcgcacgctc
     9481 tgcgcggtcg tggatgggtt gggccacgga gccctggcgg cgcaggcgtc acagctggca
     9541 gtggaaaccc tgcgcgccca tgcgcaggcc tctctgaccg agcaagtaga tcttgcgcac
     9601 cgcgcgcttc ggccgacaag gggcgcagcc cttggcattg cagaaattct tcatgatcaa
     9661 cagcttgtca aatttgtcgg tatcggaaat atcatggcgt ccatatgcca ggtgggaagc
     9721 tccagaaaca tggtctcgca gaatggcatt ctggggcacc agatcagacg cgtgacggag
     9781 tttcagtatc cctggcccga atcggcgatg ctggtgatgt gttcggacgg cattaacacg
     9841 cattgggata tcaacggcta tgccgggctg gctgcacgcg atccgagtct gatcgccgcc
     9901 acgctctacc gcgatttttc ccgcggccgc gacgatacga cggtagtcgt gctcaagaag
     9961 cgcacggcgg atgggtgaga tgcgcctgga gtgtcccgcg cgaatctgaa ggaatgacag
    10021 gatgggttcc gcctcgaaag gtcacacgcg atgagttatg cgatcatcaa tgtcgcgctg
    10081 aagtacgaag atgatgtcgt ggctgcgcgt cagcgggcca ggcagattgc cgggttgatc
    10141 ggctttgatg cgcaagatca gacacgcatt gcaacggcgg tgtccgaaat cgcgcggaat
    10201 gcctttcgtt atgccaggaa tggggcggtg gagtttctga tcgaagggca gaccgctccg
    10261 caggtcttgt tgattcgtgt gacggatagc gggcccggca tcgccgatct gaaactcatt
    10321 ttggagggac ggtatcagtc tgataccgga atggggctgg gtatcgttgg tgccaaacgt
    10381 ttgatggacc aatgcgaaat cgacagtgcc gtggggaaag gcacgagggt gctgctgaaa
    10441 aaggtctttc cgtcgaagac cagagcattg ggcgcgaaag aactctcgag cctggtggat
    10501 caattgatcc aaacgcccgc ccagaatgcg caggaggagt tacggcagca aaaccatgaa
    10561 ctcttgcggg cccttgatga attgcgtctc cgtcaggatg aactggttcg tatgaatcag
    10621 gaactggagg ataccaatcg tggcgtcgtc gctctctacg ccgagttgga tgaaaaggcg
    10681 gaccacctcc gtcgggcgga cagtatgaag acgcggttct tgtccaacat gagccatgag
    10741 ttccgaacgc ccttgagttc gatcctggcc ttgtcgggac tgctgttgga ccggtccgat
    10801 ggagaactga cggccgaaca ggacaagcag gtgcgatttg tgcgcaaggc tgcggaaagc
    10861 cttctggagc tggtcaacga tctcttggac ctcgcaaaaa tcgaagccgg caaggtcgat
    10921 gtgcgaccgg tcgagtttga agtcaaaacg atgttcagcg ctctcagggg catgctgaag
    10981 cccctgttgg caggctcgtc ggtgaatctt cacttcgaag aagcggagga tctcccgacg
    11041 ttgtacacgg acgaagggaa ggtctcgcag atcctgcgga actttatttc gaacgcgctc
    11101 aagtttacgg agcggggaga gattcgcgtc acggcgtccg tcgatgcgga gcgccgcaat
    11161 attgccatcg cggtggctga taccggcatc ggcattcacc cggctgatca agctcgaatt
    11221 ttcgaagaat tcacccagtt ggatagcccg attcagcgaa aggtgaaagg cacagggttg
    11281 ggcctgccgc tgtgtaaaaa actggccctc ttgctcggcg ggcaggtcac ggtcgatagt
    11341 caggtcggca gcggctcggt attcacgttg accatgccgc tctatcacga gaaggcgttg
    11401 gacaacatgc tgaagccggg cggcgaagcc gagagggagc tggaccctgc tcgacttccc
    11461 gtcctcattg tcgaggacca tccggagaca cggttggtct atgaaaaata tctgcggaac
    11521 agccggtatc aggcgctgcc cagtagcggc ctgcgtgaag cccgccggct cctgtatcaa
    11581 gtgcggccgg cggcgatcgt gctggatctt ttgttatgcg gcgaggatag ttggcagtgg
    11641 ctggcgcatt tgaaatcgga tgagcgcacg cgcgagatcc ccattctcat tgtcacgaca
    11701 gtcgaggatc gggccaaggc cttcatgctg ggcgccgatg cctatcaagt aaaaccgatt
    11761 gaggcaccgg tgttgattgc cgagttggat cgtctgacga agaagcggga tcacgtggaa
    11821 ccgcctgctc cggaccgtcc gcgtatcatg atcatcgacg acgaggagtc gttcaggtat
    11881 atcctcagga agtgcctttc gaatatcgac tgcgacgtca cggaatccgg ggacgggatg
    11941 gaaggcatcc ggatgtgtcg tgagctgcgg cccgacctga tcttcctgga tctcaatatg
    12001 ccgggacgat cgggctggca gtttctgcag gatttggccg cctcggaaaa gttggcgggc
    12061 acaccggtcg tgattgtgac gtcgcaatcc ctctcgaatg aggcgagaac gctgctggag
    12121 cagtccacgc ggggcattgt catgaaaagc gagttatcgg aagaggccat actgcacgtg
    12181 gtcggtgagc tgattcccga agccttcgcg cgccatcatc agtcatgatc ttttggttgt
    12241 aagaggaccg tgagcaccat ctttcagcac atcattctca atgtcgacga tgacgaaggg
    12301 gcgcgctacg ccaagaccaa aatctttgag cgagccggct atcgtgtggt cgaagcggcc
    12361 accggcgcgg ataccttacg gcttgtgcag gagcaacagc cgcacttggt gctgctcgac
    12421 attgggctgc cggatatcag cggcattgaa atctgtcgcc tgatcaaaaa gaaccccgcg
    12481 accgaacata tgatggtcct gcaggtttcc gcttcatgcg tgcgaccgca ggaacgggcg
    12541 atgggactcg atggcggtgc ggacgtctat ctgagcgagc ccgtcgaagc cagcgagctg
    12601 atcggcgcgg ccaaggcgct cctacggctc tatgatcgag agcaggagag ccgggttctg
    12661 ctcaaggaac tcaccgagcg ggaacggttc atcaaaagca tggtcgatgc ggcaccctcc
    12721 acggtctacc tctacgatct gcgtgaacag cgcaacctgt acaccaatgc ccggtccggt
    12781 gctaccctgg gctacgcgtc agatgaactg cagtttgtcg gtcgagaaac cttgcagtca
    12841 tggattcatc cggacgacag gccgctggtg atggcgcagc tggcgcaatt gccggaccaa
    12901 gcggatggcc aggtgttgga atttgagtgt cgggtccagc atcgatcgaa agaatggcgc
    12961 tggtttctct gccgcaacgt cgtgttctcg agagacgaga atgggcaacc gttgcaaatc
    13021 ctgggcacgg ccctcgacat taccgatcgc aagcaacaag acgccattct gcgtcgcggg
    13081 aaagagcagc aagcgctgtt gcttgacatc agccgcttaa tcctggaaat gccggtcgat
    13141 cgggcggcct ggaccagggc catttacgaa aaggtcgcgc cgcatctcga tgtggatctc
    13201 tgcctgaact ttctgctcga tcagaaaaca aaaggcctgc agctgctggt cggattggga
    13261 gtgcctgacg cgatgctggc gaaggcgcaa cggctcgacc ctgggcaagc cttttgcgga
    13321 tatgtcgtcg atgcgggaac gtctctcgtc gccgacgccg agttgatatc aaccgatccg
    13381 cgcggaaaat tcgttcggga gatgggcgcg cgtgcctatg cctgccatcc gttgaaagcc
    13441 agcactggag agatcctggg aacattgtcc ttcgggacca gccggaaaga acgatttacc
    13501 gaagaagaaa tcgcattttt ccaaacgctc tgccacctgg tggcgctggc atgggagcgc
    13561 catagcgtct cctccgcact gggtgaaagc gaaatgcggc tcaaggcgat cgtcgacagt
    13621 gctctggacg gcatcatcac catcgacgat cagggcacca tccatcgtgt caatccggct
    13681 gtgggacggc tcttcggata tcccgctgac gcgctgctcg gacgccatat cacgttgctc
    13741 ttgccaagtc tgtattccgt tgaaggggca gacactccgg gcgtcgatca accgcgcgat
    13801 gactcagggg tgagcggact cagacgagag atgctgggcg ttcgaatgga tcggtccagt
    13861 ttcccggtgg aattggccat cagtgaaaac catctggatg atgcggtcac ctacaccctg
    13921 ttgttacgcg acatcacgga acgaaagaag gttcaagagc aaactcggca atggacgatc
    13981 gaacttgaac agcgggtgtc cgaacggacg gaggaattgc tgctgtcccg cacgcgcctg
    14041 cgggcactcg catccgatct caccttgacc gagcagcgag agcgtcaacg tctcgcgact
    14101 gaattgcacg actacctggc gcaactgctg gtctttggtc gtatgaagct tagtcaagcc
    14161 aaacgaggga acctcggtcc ggcgacaacc ttggtgaagg aattagacga tatgctggac
    14221 gaggcgttga cgtacaccag gtctttggtg gcgcaattga gtcctcnnnn nnnnnnnnnn
    14281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14341 nnnnnnnnnn nnnnnnnnnn nnnnnnatgc tggacgaggc gttgacgtac accaggtctt
    14401 tggtggcgca attgagtcct ccggttctgc gcgagttcgg attggtggtc gcgatcaaat
    14461 ggctggcgga acagatgcgt cggcatgaaa tgaccgtcac cgtgcaatgc gaagccgatc
    14521 ttgcgccgct acgcgaggat caggcggtgt tgatcttcca gtcggcccgc gaactgttga
    14581 ttaatgtgtc gaagcacgcg aagacctcac aggcatcgat ctccgtgtgg atcgagaacg
    14641 atatgctcca tctgtgcgtc ggggacgagg gtgtcggctt tgacctggcg agcacgacga
    14701 acattgccgc gcccatgttt ggcctcttca gtatccgcga acgtatggaa gcgttggggg
    14761 gacgcatggc cgtcgaatct gctcccggcc gtggtacgaa gattacgctg gtcgttccct
    14821 acgtgggagg atcaaccgcg acggatgttc actcccgggc cggcaacgcg ctggcctcct
    14881 cgcaagtgtc tgagccagaa gcagtctccg tgctcgacgc cctggctgtg tcgcccgggc
    14941 cgcaatcggc ccattcctcc cggacccgcg tgctgttggt ggatgaccat gccatgctgc
    15001 gccaaggagt ccgaacggtt ctcgaagggt acccggatat cgagatcgtg ggcgaggcca
    15061 ataatggaga acaggcgctg ctgctcgcac agtccctgca accgaaaatc gtcatcatgg
    15121 atattaatat gccgggcatg gacggcatcg aggcgacacg ccggctcaag ctcgagcagc
    15181 ctgagacgtt ggtgataggg ctgtcggtac acaatgactg gcagatcgaa gaagcgatgc
    15241 gagcagcggg agcggtatca tttctgccga aggatgctgc catcgaacag ttgcatgaaa
    15301 cgattcaggt cgccattcgc gcagctgcca gaacggcgtg aaggccgtgg gtggtctgaa
    15361 gcaatcgcgc gtcactcgcc actgcgtggt ggaagggaat ggccggcaga gggggctgga
    15421 gcagtgccgg gagaaacgac tattccgatg acagcgatgc tggaaaacaa tgcccccgca
    15481 taaaaggtga atgccgcccc caatcgatcc cacaagaatc ccgccacaat gctcgccatg
    15541 agcatggcca gtccgctggc caggttgaaa catccatacg cggtacctct caagtcaggc
    15601 ggcgcctggt ccgccaccat cgcggcaagt aggccctgcg tcattcccat gtgaatgccc
    15661 cacagcgcca ctcctcccaa tatcacgccc caatgattgg tggtcgccag caccacatcg
    15721 gcggcaatca acaccagcag gccccatgtg agcatcgttt tgtgattgat ccggtccgaa
    15781 agcttgccga aggggtaggc agaggaggca tacaccagat tcatcgcgac catcacgagg
    15841 ggaatgaagg cgagagggat gccgccctgc tgtgcgcgca gtaccagaaa cgcctcgcta
    15901 aagcgcgcca gcgtaaagat ggagccgatt cccaccaccc accagaaggc cggactgaga
    15961 cgcctgaagt tcgcacgagt gatcggatta gctcggcggg aggatgacga agagacgggc
    16021 tcttgtatgc cgaccatgag aagcgcgacg gccagcatgc ctggtatgac ggctacccag
    16081 aagactgcgc ggaaattgtc ggcccacagc agcatgaatc cggtagcgag caaaggaccg
    16141 agaaaggcgc ccaccgtgtc caatgattgc cggaggccga acgcggctcc ccgtagctgc
    16201 ggtggtgcga tatcggccac cagcgcgtcg cgaggcgcgc cccggatgcc ctttcccagt
    16261 cgatccagca agcgagccgt caggagcgtg ccgatgtccg gtgcccaggc gaagagtggt
    16321 ttggtaaggg ctccaatcgt atacccgcaa agggccaatc ccttccgttt gcccagatag
    16381 tcgctcaatg tgcctgagaa gatcttcacc acgagggcga gggactcggc caacccttcc
    16441 accagcccca ccgcgatggt ccccgcgccg agtgttgtga ccatgaacaa cggcagcagg
    16501 ctgtggatca tttccgaaga aatgtccatc aacagactga cgaagcccag gatccagata
    16561 cccgaaggca gcttgtgacg cgagtgagag gaaggcatgg gcataactat cggcgtcgtg
    16621 ccgtgacggt tgagccgatc tgggtgctcg gcaggacaga ttataggaat tgccgggtat
    16681 ggctgtcatg tgggattccg cagattcggg taaagcgtca acagatcgtc gccctgcctc
    16741 cagtcatacc gtgtgacatc gaccagatgg ccttcctctt cgcgatcgat ccataactcc
    16801 cactggccgt cgtgattgcg atcgtaccag taaaagagtg ggtgcaacgc tacatccggt
    16861 tctgctgaag cgggatcgtc gtacgagatg cccaggatgt gacgcgctgt acgatagtct
    16921 acctggccat tcccttggag cgagtaatcg cgaaacaata agccgacgac cgaatcaaat
    16981 gtctgttcga tgaggaagtc atctcccggt tcagctggaa gtggagatcc ggcaggagag
    17041 gcggtcggca acgcgaggca gagggccaac aacattggga gacaatgagt ccatttcatg
    17101 ttcatcgcat cctcccttcg ccgcgtaaat ctgtgcctct ctcatctttg cgctgcttct
    17161 gtgtccggca ccctggaaat gtgcctagtt cagccggctc gcaaccctaa gtaggaaata
    17221 gggagcaaga gcgcactagc acttgtgttc tcaacgcgtt atgtcgattc aggtgtgacg
    17281 gcggcgttct ggccgtcacc agtacagagt ctgcggcgcg gggaatacga cgacaatgtg
    17341 gagttgctag agacagggac gatcggagaa cagcacgatg ggtatctgcc tgtgagacac
    17401 atgcaggacg acagcgccaa acagtcggga aagaaatgcg aggtcttgct gttgttgcag
    17461 cgtgacggct gcccgcaccg aggtggccca ggcctgttgt tcatccttcg acgcaagggc
    17521 cgtattcgtg aggtgtaaga gccgcccttg atgccaggcc tcgattgtgc ctggtctacg
    17581 ttcacgttga gtgtcgccgg gtgtgttggt ttctaacacc agatgtccga tcttgaggac
    17641 cgtcacgacc tcatcgcgca gggctgcaca atcaatacgg acagcgcggg tgtgatgcag
    17701 tgagtagaac gcctcttcat ctgccacata ttgccgaaag tcgctcaggt tggagagggg
    17761 aaaggtataa atgttcagga cccgacagag ggcaggcgga caccagatga ggaggagcgt
    17821 cacggccagt gccgccagcc cggccagcag gaacatcgtc ttgcgccgaa ggttcacggt
    17881 gatctcccga gagcccaccg gcaagggagg cgtgacctgt cctgaatcgc actaacactt
    17941 cattcaacta catcaatcca tctctgcccc gcccttgcca tggtagccct tgtccgagtg
    18001 ttcctcccga tagcccggat gtttgccccg acattccgat gggcagttcc ctacttacgc
    18061 ttctgacgtg gcggcgggca ggccttcggt cgctgaaggt ctgtagggat ttgggtggcc
    18121 tcatccagac aggcctggtc tagttgtgcc tgcacgagtc caagcgcgcc gctcaagttc
    18181 gcaccgcgga agttggcttg ctgaaggtcg gcgttattga gttgggctcc agtcaaatcg
    18241 gcggcggtca agttggttcc tcgcagattg gcttcctgca aattggtctg gaccatgatc
    18301 gagtgactca tgtcggcttc gctcaagtca gcggatacca gattggccag ttcaagattc
    18361 gcctcggcga gccgcgcttg ctgcaaatgg gctttgggcg catagacttc ggttagatcc
    18421 gctttctgca ggtcggctcg tgacaggtgc gcgtcgataa ggacagcatg atgcaatcgg
    18481 gcgccatgga ggttcgctga cgtcaggttg gccttgtata acaccgacat ggtcatcgtg
    18541 gcggaattca agcgagcctt ggccagattg gcgccttcga tgttggcgtt ttcgagattc
    18601 gcccgttgaa ggttggcgtt ggtcagccgc gcgtatcgaa aatctgcccc tctcaggctg
    18661 gcctcgtgaa gatccgcttg gaccagcgag gcatcatcca gataggcgct ttccaaatcc
    18721 gcctcgacca gtgaggtgcc gtcgagtgtg gcgctgtcca ggagcgcgcc ttggaggttg
    18781 gcccgtcgca gagtggcctg ccggagattg gttcggcgca ggtcggttcc ggctaggtcc
    18841 gcgtccgtta gattagcctt tgagaggttc gcgccataga aatatccatc gagcaggctg
    18901 gctccgctca ggtctgcgag ttgtaaatct gcatcctcaa aatgcgctcg ctccaacagc
    18961 gcttcacgaa agaatgcnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnncgc
    19081 ggatttcgat gcggactttg ctgcggccag cgcgccgtct ggaatggaac agagcgtggt
    19141 caccaccaat ccggcaacga atgccgcgga caaggaatgc tgattcatca aagggcctcc
    19201 ttcacaagcg tggacgccgc tcctcgctgg agcggctggt tgttcgcatg gagtcatgtg
    19261 tatcggtcga cctgctgcgc caggcgttcc agggcgccgg aaatccgaac ctcgtaaggc
    19321 tcagcctgat ccaactggcc tagcgtatcc ggaagttccg acaaagccaa tcgtgtccgg
    19381 tcgcgaattt ccaggatcga gggactcgga gccagtcgcc gccctccctc catgacttgc
    19441 cgcaggagag gccggcccgg cagagtgtcc ccttcgacgg tgattgtatc ctgtgctagt
    19501 cgtccatctg gtcccagccg tcgatagacc tgtttccggc cgggccaggt ggctttaccc
    19561 tctgaacgct tccggcatgg tctcccggca tattcctgga gtttataggc gcagtccagg
    19621 tagggcgcgt cggccgaggt ggtcatggcc gtcccgactg caaagcgatc gatcggcgcc
    19681 ccgcttgtca ccaaggcctc gatccgttct tcatccagat ttccactggc caggatcgtg
    19741 gtctcctcca gccctccgcg atcgaggatg tgccggacct tgcgcgcatg agcgcccaag
    19801 tctccactgt cgagacgtac cccatggatc gcaatgccct ggcgtttgag ttcaggggcg
    19861 agcatgacga cgcgttctgc cgccgcttcc gtatcgtagg tgtcgatgag caggaccaca
    19921 tggtgcggtt gtgactgggc aatatgtaag aacgccgtgg tttcgtcgcg gtgggcttgc
    19981 acaaaagaat gggccatcgt cccgtaggtg gggatggcga actgcgctcc ggccaggaca
    20041 ttcgacgtgc cggcaaatcc ggccagataa ctggcccggg cggccaatag tcccgcctca
    20101 gcaccatggg accggcgcag gccgaaatcg atcagcggct tcccggaggc tgcaaggatg
    20161 cagcggcagg ctttagaggc gaccatggtt tggaaattca ggagattcat caccctggtt
    20221 tcgacaagtt gcgcttgcgg cagcggcgcg gtgatgcgaa ggatgggttc gtgcgggaaa
    20281 cacaccgtgc cttccggcat ggcatggaca tcgccggtaa agcgcatcgc tcggaaggcg
    20341 atgagggtct ctggcgggaa acggcccctc tcctcgagcc atgcgaggtc gccctcggag
    20401 aaatggaact gctccagaaa ggagaggacc tgctccagtc cggccgccat gaagaaattc
    20461 ctgcgggtcg gcaacttgcg gacaaaaaat tcgaagaccg cttcgcccgt catgttatga
    20521 gcgaggtagg cctgcgtcat ggtgagttca tagagatcgg tgagcaggga ggtggtcgaa
    20581 ggtgtcatgc ggccaggctt tcgaggcgga cgggcacggc gccgagatgc aacatggctt
    20641 cctcagcgtt gcgcccgtcg tcggggtgga gattgacggc cttgatccca tccatgagta
    20701 cgcacacatc gtaaccaagc cccagcgcat ccttcaccgt gttcagcaca cagtaatcgg
    20761 tcgccaaccc tccgatgaac aggcggcgga ccttcagggc gcgtaaatgg cgatcaagcg
    20821 gtgtgccctg caatgtagaa taggcttctt tgtcctgatc gatcgcctta tagattgtga
    20881 ccgccgagac gggaggctgg aagttcggtg gcggcaagga gccgggcgat cctgcgatac
    20941 agtggacggg ccaaggcccg ccttggtctc gaaacgaaca gtggtcgggc ggatgccagt
    21001 cgcgagtgat gaaaatcggc aggcctcgag cgtggaattg tgccacgtac ccagccagaa
    21061 tcgggacgat cttgtcgcca tcctgtatgc ccaatgcgcc gcccggaagg aaatcccgtt
    21121 gcacgtccac cacgactaag gcgtcatgag aggtgaggtt cgtcatgcag caggtcccgt
    21181 ccatacgaca tcggcccgca gcggcggggc gctgcgtcat tttccctgct ggacgagcag
    21241 acggatgtag gcgagagcat cctgccgctc ggtttcggtc aattgccctt gccacgcatg
    21301 cattggactg aagacaacgc cgtgctcgat cgtccgaagc agttcttcgt cggatttcag
    21361 gaaggatttg aagcggtgga aattggccgg tggcactgtc aatccggcag catcggggcc
    21421 atctccgcgg ccgccggcgc cgtgacatgc gagacaatgc cgctcgtaca ccgccttgcc
    21481 tttggcggca tccggaggaa attcctgggc gttcgcgtcg tcgaccactg gcgccagcat
    21541 caggcctgct gcagtggcga gaatcaggtg acgaatgctg agggttgtga acgtccgcat
    21601 ggatcgctgc gtctccttta actcttcttc gtcgtatgtg cgatgaacga ggaaaaatgc
    21661 tgctgcaatt tggtgctgcc gcacgccggg cattgtacct cgcctttttc gtgctgtttc
    21721 agcgtgacga cgatcagcga ttctttcccg caatccaaac aggtgtaatc atacatcggc
    21781 atgagcgcct cgctcgcaag gtgatactgc ttttgctaat ccttgaccct gttgtcctct
    21841 tcggcctcac cccaggttgc aacgatctgg gccatctctt cgagacgtgc ggcggttcgg
    21901 ccataaatgc ttaccggcgg gtaggtgcct tctgcgccgc gttcccctgc cggcacgccg
    21961 atcagcaact ccagcgcctg gtctgccgta tcgacgccgt agacggcaaa ccgtccgtcc
    22021 tccactgccg cgacgacctc ccgattcagc gccaggtgtt tgatgttacg ggcgggaatg
    22081 atcacaccct gcttgcctgt gaggccccgc cgcttgcacg attcaaaaaa cccttcgatt
    22141 ttttcgttca cgccgccgat gggctggatt tctcccagct ggttcacgga acctgtcacg
    22201 gccagatact gccggacagg caggtcggcc agacttgaaa gcacggctgc cagttcggcc
    22261 acggcggcgc tgtctccttc gacttcagaa taggtttgtt cgaaggtcaa ggtggcgctc
    22321 aaggcaaatg gctgcatgcc ggcgaatttc ccggccagga aaccggccag cgtcatgacg
    22381 cctttgctgt ggatctcacc cgccagatcg acctcccgct gaatatcaat cacgcccttc
    22441 gtgccgacgt aggtgcgcgc ggtgattctc gtcggccggc cgaagcagta atcgcccagc
    22501 tcatagacgg acaacccatt gacctgcccg atgacctcgc cttggagatc caccatcaat
    22561 gtgccttcgg cgatttctcc ctggagccac tgctcaggca aatcggcccg gcgccgttga
    22621 tgcgccaggg cggattcgac gtccgcgcgg gtcaccaaga cgtgcccgct cttttgggcc
    22681 cagtagccgg cttcccgaat caagtcgctc accagactga agcgcagcga gagtcggtcg
    22741 tggcggtcgg cgaaccgaaa tccctggcgg atcacttcgg cgaccgcgtc cgcgccgaag
    22801 tggggcagcc cttcctcccg gcacaagcgt gaaacgaatc gcgcatactg ccgttcctgg
    22861 tgctcatcat gcggcacttc cacgtcgaag tccgccttga ccttgaataa ttttgaaaaa
    22921 tcttcctcat aggcctgcag gaggtggtag atgccggcgg tgccgacaag gatgactttc
    22981 accgagacgg gaatgggctc cggacgcagg ccggccgtgg cgaatccaaa aaattccgac
    23041 ggatcctcaa tggtcacggc tcccgtctta atcacgcgct ttaaggcctc ccaggagaag
    23101 ggctgccgca tgagatccaa cgcctgcagg atgagatacc caccattagc ctgcaacatg
    23161 gacccgggcc ggatttcggt aaagtcggta tacatgacgc caagatgggc acgtcgctcg
    23221 attttgccga tgagattgct gtaggtcgga tgtgattcgt ctatcacggg tgcgccgccg
    23281 gcagcctccc gggagacgat caaattcacg gcgaatcgtg tcaggtcggg acgtcgtgac
    23341 tgctccaggc ctggaattgc cagcatggga ccagtgtgag gcaagaagtc tctgtactgg
    23401 tgcacgatat cgtcatggac ccgctgcaga tacgtgacga cgagctgcga ggattgatag
    23461 gtttgcagga gagcgtcata ggcgcctttc atgacgttgg ccacgatctg gtggtccaag
    23521 tgatgcaacg cctgttcggc ttcccgttcg aggccgtgca tccggacatg aaactcccgg
    23581 atgtcgctct ccagcgattg ccgccgcgcg gtcagttctt cctggattga ctcagggagc
    23641 tcctccattt ccttcccagt cattgggcgg tcgtctttga tgggaacgag cgcgaacccc
    23701 cccgcggttt cctcaaacac gaatcctctc tggtggcaga ggatcgtgag atcatgaaag
    23761 agattcttct ttttatcttc cgtctcttcg atgattttcg ccttggcatc gagatacttt
    23821 ttcccttcga aggtcgtggg aatgtctcgg cggagacctt cgatgaaggt gctcatatcg
    23881 cgtttgaagg acgcgccttg ccctgctgaa aacgaaaggc aggacgggcg cgaggcgtcc
    23941 tggaaattat ggacaaaaca ccaatccggt gggggcggag cggtctgagc caggcgttga
    24001 accatctgtc ggactagcgt ccctttgccg gttcctacag ggcccgacac gaagatgtta
    24061 aacccgggac tcttcatctg caggccgaat tccaatgcct cgaccgcccg ctcctgtccg
    24121 atcgtctcct cgagcggctg cacctggctc gtatcggcaa atcccaagcg ggccggatcg
    24181 accgtcggag ccaggagaga agccgggagt ctatggttgt ccagcatcgt gtacgtccta
    24241 aagcttgagg agatgcggtg gctgaacgat ggtggcgtgc aagcccttct cgccgggctc
    24301 gctttcgaac aacacctcca ctccgtcttc caagtcggcg aaggccatgc ccttgaccgc
    24361 attcttgtga aaatacacct cgccgccgcc gtccatcaga atgaagccgt acccttgttc
    24421 aggaaagacc ttgctcacga caccgcgccg ctgcggcaac ggttccacgc gaatgacctt
    24481 gtccgcgcgt ttctcgcgaa attttttcaa ctcgatcgcc acggcatcga aggcggaccg
    24541 gatcgcttct tcgaaggtct tatcctcttt gcgtgaagta atggtctgcc gcgagggcac
    24601 cgtgacgagc acgagcgctt cggcgacatt gtccagtttc ttgtgatggc gatttttggt
    24661 gagcgtaacg cggccgtgga tgatgtcgtc atggccacgt tgcaaagcgg ccatgcgttc
    24721 ttcgatttcc gtcttccagc ggggagtcat ttcgatattc cggctttcca cttccaggtt
    24781 catgcgtcct cctctcgtct cagatggaac agggactctc actgctctcc tcagcaaggc
    24841 acatgcccct gacaatcagc ctgtatggcg gtcgaggcaa gggtgaatcg gctcaaagtg
    24901 aggcattttc atgggaaggc ttactacgcc gggcggaggt ctgcatacca ctggcgcata
    24961 attcctcact tgcctgaatg gggttgaagc ccaatgcacc agtctcggct cgatgtggcg
    25021 ggcgtggcta ctccttttcg ggaacatgtt ttgcgtacga gccggatatg ccggtattga
    25081 agaaatccgc cctggacggc tacgtcaaag cacggttcgg ttcgacggcc gaattggtgg
    25141 cctatggccc catcggaaaa gaaacccagg gtgcacgata caaacagtac gggtatggcg
    25201 cgccgatccg attaaccttt cgtacaaacg gcaacaaaac ccgccaagtg gtgctgggta
    25261 cgatgagtcc cggtccgttc ggccacgagc atccggctga cagagcccag gcgatgttga
    25321 tggactatga ctgttacagc cggcttcccc ggcatatcac ggcgctggac gtaggcgcgt
    25381 tcaccgcgcg tggcgagttg atgtcggtcg cggcggccaa agagttcttc ctgctgaccg
    25441 aatggtcgga aggggacacg tatcacaagg atctcgaacg actggcggac gcaaccaggc
    25501 ctaccccgtt ggaccggaag cggacacagg cgctggctga ctatttggcg accattcacc
    25561 gcgtgaagcg cagagatccg caactctatc gccgccgctt gcgcgaattg ctcggccacg
    25621 gcgaatgtat catgggactg accgacagtt atccgcatcg ctatggtttc atcacggagg
    25681 agttgctgca acgcatcgaa gtcgcctgta atgcctggcg ctggcgattg cgccgtcaac
    25741 atgcgcgtct ctcacaagtg catggggatt ttcatccctg gaacgtgttg ttccgccggg
    25801 gagccgactt ttcggtgctt gaccgctcgc gtggggagtg gggtgagccg gcggacgatg
    25861 tgacgtcgat gtcgatcaat tatctatttt tctcgctctg ccggcatggc acgttgaaag
    25921 gaccgctgga ggtgttgttc cattcgttct gggaccgcta tctaagcagg agccacgatc
    25981 aagacgtact aacggcaacg gggccgtttt ttgccttccg ggggttggtg ttggccagtc
    26041 cactctggta tccgaagttg accctgacgc tgcggcgaaa aatattccgc ttcattgaga
    26101 atgtgctggc cgtcccgcgc ttcgatccgg ccgatgtgaa tcggtactgc gattagtaca
    26161 gtcaaagtcg cagtcgcgcc tcgtgcaatg aggcggctct cacatggtga acatgacgat
    26221 ggcgcccttt gccctatggc tcaccggcct cccggcttcc gggaaaagtt ctatcgtggc
    26281 caggctgctg cccaagcttg cttcgatgga tatgaccgcc gaggtgctgg agtcggatgc
    26341 cgtccgccgc attttgacgc cggaggccag ctattcgaaa gaggaacgcg atctgttcta
    26401 ccgggccttg ggcttcatgg gagcgcgatt gctggcgcat ggggtgaatg tgatcatcga
    26461 tgcgactgcg agccgtcggg cctatcgaga gtttgcccgc acgctgattc ctgatctgtt
    26521 ggaggtctcg gtcgaatgcc cgttgcatgt ctgcatggag cgggataaga agggaaccta
    26581 tcggcggggc ctgcaaggcg aatcttccac tgtgcccgga ttgcaggaac cctacgaagc
    26641 gcccctctcg ccggacctgg ttctcaatac cacggagctg ttgcctgacg ctgcggcgga
    26701 tcagattgtc aggctgatcc gtgcccatcg tcagagttga ccccgactgt atggggtatg
    26761 gttgcctgaa tggtctacat gcggcggcgc tcggtctctt aggcgccccc ttgctcgata
    26821 ccatagcctt tctttaggat gacttcgtcg gcctgatcgt tccccggagg gcattcatgc
    26881 ccgcctcgct caaacacatt gatcgcgata ctcccatggg agctacgctg gtgggcggcg
    26941 gcgcaacgtt ccgctgctgg gctccgcatg ccaaggccgt gtacgtggtg ggggatttca
    27001 atcatcgcat ccgcaacgac gcagcactcc tcacgcgaga tcagcagggg cattggcgtg
    27061 gtttcttccc cggggtgaag gatcgtcaac ggtacatgtt ctacgtggtc ggcgagggga
    27121 gcgaggggct caagcgcgat ccctacgccc gtgaattgga atcgcccttt cccgccgaat
    27181 gcctgattcg gcgcaccgac tttccctggc atgagagcgg ctatgtcacc ccgccgtttc
    27241 acgagttcgt gatctatcaa ctccatgtcg gcaccttttt cacgccgaac ctgccgcaca
    27301 agggcggcac gtttctcgat gtcgcgcgca agctgccgta tcttgccgat cttggcgtga
    27361 ccgcgttgca actcatgccc attcaggaat ttcagaccag cttcagtctg gggtacaacg
    27421 ggaccgacta tttttcgcct gaaatggact ttgcggtggc ggatgctgag ctgccggact
    27481 atgtggcaga ggtgaacaag ctgctggatg cgaaggggct gcgccggtat cacgcggctg
    27541 acttacacgg ggaaatgaat cagctcaagg cgctggtaga cctggcccat cttcacggtc
    27601 tggcggtgct gctcgatgtg gtctacaacc atgcgggtgg ggagttcggc gatcaaagcc
    27661 tgtatttttt cgaccggcag gatcccgccg gcggtcagtg gaattctctc tactttacgg
    27721 accggggcca cgcgggaggg ctggtattcg atttttccaa gccggaggtg cgcgactttc
    27781 tgattcagaa cgccaaattt tttctcggcg agtaccggat cgatgggttc cggtatgacc
    27841 aggtgagcgt gatcgatcac gatggtgccc cggacgggtg gcgtttctgc caggacctca
    27901 cctccaccgt gcatgcgcaa cgaccgaaga ccttgcacca tgctgaatat tgggatgtga
    27961 atccctttat catcgcgccg ccgccggttg gtgccgggtt cgatacgacg ttgaccgatg
    28021 gactgcgaat tgccatacgc gatgtgattg ccaacgccag cgctccggac gaacggccgc
    28081 tccacatgac gcagctggcg cagagtctgt ggcctcaggg tttttctgag tcatggcgtt
    28141 tcgtgcaggg gccggagaat cacgacatcg tctataacgg tcgagaagcg cgtatagcgc
    28201 ggctgggcga tccggaccat ccccggtcct ggtttgcgag gagtcgggcg cgtgtcgcga
    28261 ccggtctcag tctgacggca ccggggattc cgatgttatt catgggacaa gagttcttgg
    28321 aggataaaca gtggtcggac gactttgtgt cccaccgcga tctgctgctg tattgggcgg
    28381 gcctcgatca gggcgacagg cagatgctcg atcacctgcg gttcacgcgg gaactgttgg
    28441 ccttacgccg tctcttgcct gcattgcgcg gccgtgggtt ccgtgcgacc catatgcatg
    28501 accagaatcg ggtgctggct ttccatcgtt gggtggaggg ggaaggtcag gacgtgatgg
    28561 tcattctgca cctggccaac ttcactcgtg ttggatatca aatcggcttg cctggcgagg
    28621 gagcctggcg tgaagtgttc aacagcgatg tgtatgaaaa ttgggtcaat gccggcgtgg
    28681 cgggcaataa cggccgcgtc ctggccaacc cgcagccgct tcatggtttt gggtactccg
    28741 ccggcctcgt cctgcccgca aacagcatcc tgattttcgc ccggtagcca tctggtgttc
    28801 agtgcgtgag tctcctgtat tcccgcgact gtcatgcctg ctccttcttt ctctcgcaag
    28861 gccataaggc ttttgcgtag cacagacgac ctcaccgtgc ggccgatatt ccacccggaa
    28921 ttagcaccat cggcgacaga cgcccccacg taccggcgat acagtgacgg agtccggcaa
    28981 agaactcatg tgtggtcgtg ccatggcacg ggagaggagg tcatgatgac tcggaaaatc
    29041 ctggcgactc tcatgtttgt gtggggcatc ggactagtca gcctggctca ggcatttcaa
    29101 actgcagtgg tctttcccgt cagttcagtc gagcatgtgg attcacgcaa tcaagtcctc
    29161 acgttcaaaa cgcaggatgg acaggtgcgc atgttccggg tggcccaatc tgtgggcatg
    29221 aagcgggaat cgttggcgaa gggtgacctc gtgcgtatcg aagtcgatct cgacgaccag
    29281 atcgtcaata tcgtgaagtt gactcagacc tcactgtccg atcgcgaagc gctgcgtcgt
    29341 aaatgagtct ccatccatga gtcaatgtga taggcactcc cgcgaccggg agcgggaggc
    29401 taggtggtcc accaggtgac aacaggggga tgtggcctcg tgcggagggg ccgtggatga
    29461 acccaccggt ctaccagccg aagtcctgcc ctgcgaccat aatccgcggc gatggccgct
    29521 tcgtcgctcc cctgattcac cataaagaag agaccttgtg acgtgagatt gcgagcgatc
    29581 ctgtcgaaca gtcgttcagg ggaaaacacc gtgagtggca gtcgccacgc cagtacaggc
    29641 gatggtgtca cgaacggaaa ccaggcggtg atcacgtccg ccttggtctc cacctcgcaa
    29701 tagttcgcga ccagaaatga agtctgcgaa agccccgcga tatatccacg ggcggcatca
    29761 taacggctgt accccgtcgg gtagagccgg aatccctcca catccacacc cgtcaacgtt
    29821 gcaggacgga agaacgcgtg caaggtgcgc gcataccaaa agtttgcgca gcccacatcg
    29881 gcaacgacgc ctccctgagg gaccggccgg ttcgtgtccg tccatgcctg gtgcaacaga
    29941 tcgagatagg catagttggc cagcgcggta tgctggccgt agtgagtttc gaagcgcagg
    30001 tcatatcgca cctgcaattc attgatgcgc gcgatctgcc aggaggtgag tccggcaagg
    30061 cagccgatcg gtttttcatg atacggctgt ctcgaccacc ggatacgttc cgacaggcga
    30121 aaccacagct catgatagag cgagcggcag cgttgaagga gagaatagtg gtcgtccggc
    30181 ggccatgcgc gtgagatgtc cggtgtcgtc gccataccgg gaaagtgtct cgtaggtcgc
    30241 cggcttttcc aatgaaaaac gcaatggaga ccatcggctc acgcgagtgg atgcctgcgg
    30301 gccactcatt cggactcctg ccggatcaac tccttcacca tcctccggtg cggaatacca
    30361 gcatccatga atagctcgcc gatcacgtgg aatcccgcac gttcatagaa cccgatcgcg
    30421 tgagtttggg ccgacagcgt cacgcgtgtg agcccttgtc gcactgcgca ctcgagtaac
    30481 gcctcaagca acgcacggcc cgcgccccga ccacgccaat ctttgaggac ggccatcctg
    30541 ccgatcgtgc cctgtgcttg catgcgcgcg gtgccgatgg cgtcaccctg tttattccag
    30601 gccagcacgt ggacgcattg cgggtcgagt ccatcccact ccaactcttc gggcaccgcc
    30661 tgctcccgga taaagacggt ctcgcggata gggcggatca gttgttcggc atggacccaa
    30721 tccaccagtt ctacgcgaat aggttcgcca gcctgcgtca cagcatgccc tccaaggtaa
    30781 agcccacaat gtgccttcaa tcgcggtggg aatcaaccgg agggacaggg cctgcgtagt
    30841 aacacgtcag cgcgaccgag ggctggtcgg atcaaattcg attctgtttg ggaggattgc
    30901 caatggcatg ttaccgtcat gatcaggaga ttggtgcgca tgcccatggc gtgcgcctgc
    30961 tctccggtga caggaaggag gatgacgagt gaacattcaa cagcggcggg ctcgagtcgg
    31021 atcgctacgg aagacgcggg cagggatgtg gcgtgcctgg tgccatgccg gcgcgaaaga
    31081 ggcacggccg tccgtcttca gttgggactt cctgcgctcc gtctggtctc tgctgtgtcg
    31141 catgacccgg aacaaggggg tgcggccgga tgagaaccgc ttcgcgtggc aagaacacat
    31201 cggctgcacc gctccgcgtt cttccggaat ctatgggcgc atgatctgat accaatcgga
    31261 tctctttctg cgagtacctc cagcccacaa gctctcttcc tttcgccatt ggtttacggc
    31321 gctgtcctgg cagaacatcc accggtcggc gtcaacaagg tgatgccgtc cttgaatcaa
    31381 cctcgtttgc ccagatcttt tcatcgctgc cgccaaagat gctattgacg cgtcgcccgg
    31441 ttgaggcgaa gatgcggcag cgtggcgcag gttttgctca acaattctgt attcttggca
    31501 acagatcgaa tgataagggg caacctatga aggtattgat tgcgacggat ggatcgaagt
    31561 acggcaagtg ggcgaccgag tgggtggcga gaatgccctt tgccgagaag ccggaagtgg
    31621 ctctgctgca tgtgacggat gtggaagcct tgcgcgcgcc gttcatgttt caaccggtgg
    31681 tcatcggcaa cgagccgttt atccaggaag aaatcaagcg tattgaagca cgaggaaaga
    31741 cggccatcac cgaagcgaag gcccagatgg cttccttgaa gctcaaggga aaggtgcagt
    31801 cggagcgggg gccggcgggt cccacgattc tggatcgggc gcctcgccgg gacggcatcg
    31861 tggcaatcgg gagtcgcggg ctggacgcac tcgaccggtt tatgctcggc agcgtctcga
    31921 cgcaggtcac cctgcatgcg ccctgctcgg tgctgatcgt caaggaagag ccgcgcccgg
    31981 tgagccgtat tctctttgcc gcggatggat ccaaggcatc ggagaaggcc ttacggtttc
    32041 tcctgaccaa gcttcagccc gaagcccggg aaggatttga gccgatcgat gtggtggtga
    32101 tgcatgcgat gccgttcctg aagtatccgg agctcaaaga ggccggtgcg cgtctggtgg
    32161 aacaatgtgc caacaaattg atcaaggccg ggtatgtggt cgatgaagtg gtgcaactcg
    32221 gtaaacccgc cgacgagatc ttgaaagtgg catccaagaa gaaagtggat ttgattgtga
    32281 ccggtgccaa ggggatggga gcggtcgccc gcttcctgtt ggggagcgtc tccaccaagg
    32341 tcgtgcagca cagtacctgt tcggttctcg tcgtccggta aggtgcgact ctccagcggc
    32401 gccatcttgg agaacagaag accgctgtgg catttcaccc cgtatccctc ccgcaagcgt
    32461 agcaaaacgc tgccatgggt gtgtcattcc ttgtgaaatt tcggctcgcc cgcggcatgg
    32521 tccctgctgt ggttatacac ggcagggaca tgcagaacag acaatggaca catgaccgat
    32581 cgagtggcgg ctctcacatg tgagttcaga cggctgcttc cgcggccggc ctgttcgctt
    32641 cacctcgcgg gtcgcgcgct cctggtagtg ctgctgatgg ggcaggtcgg gtgtgatcga
    32701 gatccggggg tgccgccggc cgctaagcct gtgagcagag cggctgatgg aatcgtacaa
    32761 ctgaccgcgg cagaaatcgg gcgggctggc attcaggtgc agagagcggc aaaagaaccc
    32821 tttgtcctgc atcgcgaatt tccggcgacc gtgcaagcca atgaaaacga attggcagaa
    32881 gtcaccacgt tgattcgggg ccgcgtggta gacgtattgg tcgatgcggg caaggatgtg
    32941 aagaagggtg agcggctggc cttgctcgac agcactgatc tgggcatggc cgagggggtg
    33001 tatctcaagg cgacggcgcg gcaacatgaa gcgcagctag cgcatgaacg ggcggccaat
    33061 ctgcatgagc atcgtgccat cagtctggct gagttgcaac gccgggaagc ggaaatgaaa
    33121 acggcgcagg ccgaggcccg agaggcggga catcggctcc ggctgctggg cgtgccggac
    33181 caggagattc agcggctgga acgggagcga accattcgtt ccgacatcgc gatccgggcg
    33241 ccgttcgcgg gccgcgtgat catgcgaaat ctcacgcgcg gcgaagtcgt ggaaacctcg
    33301 cggaactgtt tcaccatcgc cgacttgtca gatgtctggg tgatcgccag tgtgccggag
    33361 aaagacgtgc agttcattca tcccaaccag acggtccatg tcatcgtcgc ggcttatccc
    33421 catagcctgt tctccgggcg catgacctac atcagcgatg tgctcgatcc gaccacccga
    33481 acgatgcgca tccgtgtgac cgtgccgaat ccggatcgtg cgttgaagcc ggaaatgttt
    33541 gccatggttc gcgtcgatgc ctcgccacag cccgctgtgc tgactgtgcc gttgtcggca
    33601 atacagcagg agggcggggg caaaatgttg ttcgtgcggc aaggggagaa tcgattcgcg
    33661 ccgcgccgcg ttcagttggg cgatgaacaa gatgggcagg tcattgttct ggaggggctg
    33721 cgggaagggg aggacgtggt cgtcaaggga gcctttgcga tcaagtctga actcgatatc
    33781 cacaaaatcg agcccactca atgattgctg cgctgctcga attctccctg cgccaacgaa
    33841 tcctcattct cggcctggcc tgcttctgcg ccgcggccgg tgtcttcgcc ttccagtcga
    33901 ttcccatcga cgcctatccc gatgtgacca acgtgcaagt gcaggtgctg acggaagcgg
    33961 ctggactctc cccggtcgaa gtggaacggt tcattaccta tcccatcgaa ctgcaaatga
    34021 acggattgcc gggcctgacg gaaattcgct ccatctccaa gttcgcgctc tctcagctga
    34081 cggtggtgtt cgaggacgat gtggatgtgt actttgccag gcagctcgtg ctggaacgaa
    34141 tcatggcggt gcgcgagcgg ttgccggccg gcatggagcc tgttctggcc cccgtgacca
    34201 ccgggcttgg agaaatctac cagtattacc tcgagggcgg gacgaagccg gatacgaatg
    34261 cggcgctggt ggaagaagcg ctgacgaacc agcggaccat acaggactgg gtgctacgtc
    34321 ccctgctgaa gggcgtgccg ggcgtcattg atgtgaacag cctcggcggg ttcgtgaaac
    34381 agtatcaagt cctggtggat ccggacaggc tacgcaagta cagccttacg ctgcatgacg
    34441 tcttcgatgc cgtggaacgc aacaatgcga acgccggagg aaatgtcctt gaacgccatg
    34501 ctgaacgcgc cattgtgcgc gggttgggcc tcatcaaaag cctggccgat atcgagcgga
    34561 tcgtcgtcaa ggaggcgggc ggcgtgccgg tgtttgtgcg tgatgtggcg gaggttcgca
    34621 tcggccatgc ggtacgccac ggcgccgccg tgctgaacgg cgaacgggag gtggtggccg
    34681 gcaccgtgtt gatgctgcga ggcggcaacg cgcgtgaagt ggttcaggcg gtgaaacaac
    34741 gggcggaatc catcgagcgt cagggaattc tgcccggcgg actgaccctc gtgccttttt
    34801 atgatcgcat tgagctcgtg acggccgcca tccacaccgt gcgcgacgca ttgatcgaag
    34861 gtgtcgtgct ggttgcgctg gtcttttttc tcttcctcgg tcatgtgcga agcgcgatcg
    34921 tcgtgacggt ctcgctgctg gtcacgccgt tgatcacgtt cgtggtgatg cagcgtgtgg
    34981 gactctccgc caacctgatg accttgggcg gactggcaat cggcatcgga gaaatcgccg
    35041 acggctcgct ggtcgtggtc gaaaatattt atcgccactt gtcagagaac cggctgcagg
    35101 aacgatcccg cttagaggtc gtgctgcggg cgacgaatga ggtcgggcgg ccgatcctgt
    35161 tcggcattct catcattagc gtcgtctttc tgcccttgat gaccctgcac ggcatggaag
    35221 gcaaaatgtt cgcgcccctg gcctatacac tcgtcatttc cctgttggcc tcggtgatcg
    35281 tgacactgac cctgtccccg gtcctcgcct ctctgatctt acacggcgat catccggagg
    35341 agactcgtct cacccgctgg atgaaggcgc agtatcaacc ggtgcttcgg tggacgctgg
    35401 accatcgcgc cgccgtgctg ctgagttcaa cggcgatcgt gctggccagc ctgagcctgt
    35461 tgccttccgt cggccgcgaa ttcattccga tcttggagga gggggcactg accccgcaga
    35521 tcgtgcgcct gccgagtgtg tcgttggacg aatcgatcgc catagaaaaa caaacccaaa
    35581 aagtcatgct ggagtttccg gaagtgcgga tgtcagtcag taagatcggc cggccggaca
    35641 tcgcggtggg gccggaagag cccaatgaaa gcgacccgat cgtggcgctc cgcccgcgtg
    35701 aggcgtggat caccgcgcag acgcaagcca agctggtcga tgctatcagg acacgtctgg
    35761 cggaaatccc cggtatttcc gtgctgatga gccagccgat tcaggagcgg gtggacgagc
    35821 tgatctccgg catcaggacc gaatgcgcca tcaagttgtt cggcgacgat ctcgatctgc
    35881 tgtatcagca tgccgaacgg atcgccgatc tcatgcggac gatcgacgga gtcaaagacg
    35941 tcaaggtcga acaggtcgcc ggtcagccgt acctcacgat cgatatcaat cgagaaaaga
    36001 tcgctcgata cgggatcaac gtgtccgatg tgcaagacat catcagcacg gcggtgggcg
    36061 gaagaccggc gacccaggtc tatgaaggcg agcggcggtt tcaactggtc cttcgatttc
    36121 ctgaatcgtc ccgcaacagt atcggcgcga taggagatat tcgagtacga tcggcgtccg
    36181 gtgccccgat tcctttgagc gaactggcgg cgatcgagat gcgggaaggt ccggcgcgaa
    36241 tcagccggga acaggcgaag cggcggatct atatcgggtt caatgttgtg gggcgggaca
    36301 tcggcggcgt cgtggatgaa ggccggaagc gcttggccga gcagctccga ttgccgcaag
    36361 ggtataccgt ggcctggggc ggcgcatttg agaatatgga acgggcgaat gcgcggttgc
    36421 ttgtggtggt gccgatcacg ctcggcctgg tgttctttct gctcttttgg gcgttccatt
    36481 cgctgcggta tgccgggttg atcattctga acctgccctt cgcgttgatc ggaggcgtgg
    36541 tttccctgtg gctgagcgac cagtatttga gcgtgccggc ctcgatcggc ttcatcgaac
    36601 tgttcggctt ggcggtcggc aatggcatcg tgctcgtgtc gtacatcaat caattgcgga
    36661 acgaagggca gcagacagag gcggcaatca tctcgggctg cgtcctccgg cttcgaccgg
    36721 tcgtgatgac gatgatgacg acccttctgg ggcttctgcc tctggtgttg gcgcagggga
    36781 tcggcgcgga agtgcagcgg ccgttggcga cggtggtgat cggcggcctg ttcacgtcga
    36841 cggctttgac cctcttggtg ctccctgcct tgtaccgtac gtttgccgaa caggacgtga
    36901 cgaaggaaca tgctcccgag tgggtgtagc ccgatgccgg tgtggaacca tgctcaagca
    36961 gacaccattc tggtctcttt ccgccgatga tgtgttgcgg caattgtccg ccacaccaaa
    37021 tggattggcg acagcggagg ttgacgcgcg gcaggccacc tctgcatccg ttcggctgaa
    37081 gcctcagcgc aatagccggc cgctgcgctt gctcatggcg cagtttcgca gtcccatcat
    37141 tctcattctc ctcttcgctt ccggggtctc gttttttctc gctgagcata gtgatgcgct
    37201 catcatcctg accatcatcc tcgtcagtgc cctgctgagt ttctggcagg aatatagcgc
    37261 ggcccgggca gtggccggcc tattagctct tgtgcaaatc acggctcggg catggcggga
    37321 tggcgagctg cgcgacattc cggccgatca catcgtgcca ggcgacgtca ttgagctttc
    37381 cgccgggtcg agcctaccgg gtgacgcctt ggtgctggag gcgaaggatc tgttcgtcga
    37441 tgaggccacc ttaacgggag aaacgtatcc ggtcgagaag tcggtaggct cactaccggc
    37501 tcatgcgccg ttggcgaagc gtaccaacag tctgtttctc ggcacccatg tcgtgagcgg
    37561 gcaagcccgg gttgtcgtcg tggcggtggg aaccgacacg gaattcggcc gcatcgccca
    37621 tcgcatggcg ctcagggcgc ccgagacgga attcgaacgg ggcgtgcggc gattcggcta
    37681 tctcctgctc gaagtgacgc tgctgctcgt gctcgcgatt tttgccgtca acgtctatct
    37741 tgaacggccg gcccttgaat ccttcctctt ttccatggcc ctggcggtgg gactcacgcc
    37801 gcagttgctg ccggccatca tcagtgtgaa cctctcgcac ggcgcgaaac gcatggccca
    37861 acagaacgtc gtggtcaagc gcctggcgtc gatcgaaaat ttcgggagta tgaacgtgct
    37921 gtgctccgac aagacgggga ccttgaccga aggctccatg cgactgcatg ccgcgctgga
    37981 tctggatggt cagccgagcg agcgcgtgct gttccatgcc cacatgaacg cgatgttcga
    38041 aactgggttt ccgaatccct tggatgaggc cctgcggcag catcgttcct tcgatctcgg
    38101 cagctaccgt aagctggaag aggaaccgta cgattttgtt cggaagcggc tgtcggtgtt
    38161 ggtcgccact ccgcagaccc atctgctgat tacgaaaggc gcggttgaaa gtatgctgtc
    38221 ggtgtgtctg catgccgagc agcagaacgg gtccctcatg ccgatggatc aggttcgcgc
    38281 atcgatcagg gagcaggtgc gggggctcag cagcgagggc taccgtacca tcggagtggc
    38341 ctatcgggat ttgggagcca tcgaccgggt ttccaaagag catgaaacgg gaatgacctt
    38401 cctgggcctg ctagtgtttg tggatccgcc gaaggccggt attgtcgaca cgatcgcgct
    38461 gctccgcaag ctgggggtgt cgttaaagat ggtgacgggg gatcaaggac tggtggcggc
    38521 ccatgtgggg cgacaggtcg gcctggccaa tccgcgcttg ctgaccggga gtgacttgcg
    38581 aggcatgacc gacgacgcgc ttcgggcccg ggccaacgaa gtggacattt ttgcggaaat
    38641 tgaaccgaat caaaaggagc gcatcatccg tgcgctacgc ggttccggga atgtggtggg
    38701 ctacctcggc gacggcatta acgatgcgcc tgccctccac gccgcggatg tgggcctttc
    38761 ggtcgatggc gctgtcgacg tggccaagga agccgccgat cttgtgctgt tggaacatga
    38821 tttgagcgta ttggtggaag gcgtgcggga ggggcgacgc acgtttgcca acaccctcaa
    38881 gtatgtgttc atggcgacaa gcgcgaattt cggcaacatg ttcagcatgg ccggtgcctc
    38941 gctgttcttg ccctttctgc cgttactccc gaaacaaatc ttgctgacga atgtgttgac
    39001 ggacattcct gaaatgacga tcgccaccga tcatgtggac tctgaattgc tcgatcgacc
    39061 gcgccgctgg gatattccgt tcatccggcg gttcatgctg accttcggat tggtgagctc
    39121 gttcttcgat tacctcacgt ttggcatctt gttgttcctg ctgcacgcca cgaccgccca
    39181 attccgtacc ggctggttcg tcgaatcggt gctatccgcg tcgttgattg ttctggtcat
    39241 tcgtacgcgc cgcccttgcg tgaccagccg cccgtctgcg cccttgttgt ggtcaacgtt
    39301 gctgattgca ctggtcacga tcctgttacc gataacgccg atgggttcat ttctgggttt
    39361 tgaaccgttg ccggctgtct tttgggtcgc gctgctcggc attctcctgg cctatgtcgc
    39421 ggcggcggag ctggcgaaaa cgttctttta ccggcaggtc aataacggcc gctgatcagg
    39481 cgacgcgacg cgcttccata attcctacgt accgcccaag ccagacaatc gatcatctcc
    39541 ttgactgtac gtggtgatgt agtacaacca gagagagggt attcgttcaa cattcttcca
    39601 cgcccaatcc gcacgaggac gcccatgccc ggttctccgc actcccccaa tggtctctcg
    39661 tatgatccgc aggtgctcct gaattcccag ccggtcatcg tgaccgtgat cgatcctgcc
    39721 gaccattccg tgcagttcca aaaccagacc ggtctgggag cgttcggcga catggccggc
    39781 tcgccctgtt atgaaaaaat tgcgggaaag acggcgccgt gcgaattctg ccgcatgcct
    39841 gaggcgttga gccgagatgg agtggtctct gagcaggtgg aaatgccgaa cggccgccat
    39901 ttactggtgc attgggcgaa ggccccgaca aaagacggcc gtgtccatgt cattgaaacc
    39961 atcatcgatc tgaccaagcg caaacaggac gaacaaagcc tgcggcaatc gcagaaaatg
    40021 gaagcgctcg gccgattggc cgcgggtatc gcccatgact tcaataattt gctcatggtc
    40081 gtcatcggcc atgcgcaccg agtcgcgcag caactgggat cccatccgct gcatcatgaa
    40141 gtggaaatga tcggccaggc cggcacgcga gccgcggcgc tgacgaagaa attgttgacg
    40201 ttcagtcgac gccaggtgct cgagcagcgt gacgtgccgc tcaacaccct gattcgcgac
    40261 atggaagaca ttttgcgtcg attgatcggt gagcagatcc agacggtgat tgtgctccat
    40321 ccccaggcgg gccacgtctt gggcgacccc gtgcagatgg agcaggtatt gctgaatctg
    40381 gccctgaacg cccgcgatgc catggcagaa gggggcattc tgacgatcga gaccggcaat
    40441 accgatgtcg acgagcagta tgtgcgcact catcccggcg cggttcccgg tccttacgtt
    40501 accctggtgg tcgaagatac gggatgcggg atcgatgccg agaccctcgc ccatattttt
    40561 gaaccctttt tcaccacgaa ggaattcgaa aagggaaccg ggttggggct ggccaccgtg
    40621 tatggcatcg tgaaggagag ccgcgggtat atcgatgtca ccagccaacc tggacggggt
    40681 acgcgtttta cggtgatgtt gccacgcgtg cagtcgcaaa catcggaagc tgaacagccg
    40741 gcatcctcac gaccgcttcc ggcgacttgt gccaccattc tcctggtcga agacgatgag
    40801 ggcattcgac ggcttgtggc ggccgtgctg cgtgatcagg ggtatgaagt gttggcggcg
    40861 gcggacggcg tcgaggcgct gcagatgttg caactacgca agggcggctg cgatctcctc
    40921 atcaccgacg tgatcctgcc acgtatgaag gcctcggttt tggcgcaggg agccaggacg
    40981 atgtttccca agatcaaggt gctctatatc tccggatatg ccggtgacat gttggtatct
    41041 catggagtgg atgcacaagc agcctacctc caaaaaccat ttatgccgca ggccattatc
    41101 gaaaaagtgg ccgaattaat cccgcccgct cctgcgcagt aacgagctcg tatctattgc
    41161 gcgtggatgg tcgttcaccg atccgcttgc gtgatctcct tcgagagtgt ttcgtcttct
    41221 tcgtaccgcg ccccgcgttt tgccccgcgc gccactgggc gacggattgc acccatgcgt
    41281 catggccaaa cagggcagaa ctcaagattc tggctggtac tcggtggttg tgcgaggcag
    41341 ggaacttatt tccaggagac gccgggaaga gaaatgaccc gttccgtttc ggctgtcgac
    41401 tgcgcgtcca gaagaaggtc gtacacgagt ttgacccggc tgcgcgtttc tgccgaaagc
    41461 gccaggaatt ccacgccgaa ggcatcctta ctcgtccacg tgacgacggc gggcttgatt
    41521 tcgatcggtt cgatgcgatc gggaagcgag atccgcagcg tcaatcgcat cccgcagtga
    41581 accttggcgg cagtctgttg aatcttgcat ccgccgggtg aaaaatcctt caccacaccc
    41641 tggctggttc cacgggggcc ttgcacatcg atcggccgat tcatctcgac acgcgtattc
    41701 ttacgttttg acatcccttg gtccttttgt aatcggcggg tcttccaggg ttcgcacggt
    41761 ccttagatag ctggctgcat gagcgattcc gttaatgttc taaacgcggg atccagcatg
    41821 aaccgaccga aggatacatc ctgccggggg tctggtatgg gttctcggtc gttgctgcga
    41881 cggaagtgca gaaatgcgtc gtgcagagat tgcatggccc ggtcacgttc attcattccg
    41941 gcgtaggtgc gggcgagatc atagtgaaag gatggattcg cgggctcttg tgaaagacca
    42001 tagtcgatcg ttgttttagc gcgggcgaga tcaccgctcc tgcgataggc gacacccagg
    42061 ttatggacga gcagacgcca gagagccttg tccaaagagg ggttcgtccg ctcaagggcg
    42121 acggcccgtt catagtgcgg aatggcctgc ttgaattgtc cctgcagata cggcgcgctc
    42181 cctgcacgaa agtaatccag gctgccgggc tgggccgccg caacgatgga aaggctctcc
    42241 agcaccttcc gaagttgcga ggcgtctact gttgtggtgc cgctgtgtga cagatgaatg
    42301 tcggtataga cgttgtcttt gttcgtacag gcaaagaggt gaacctggtc cgtccacccg
    42361 gcgctggtct catacagaag atattcgaag accgggagtt gattgatctc ggttcgtgtc
    42421 ggacctgcat gggatggtgc cgcagctgtt tgtgcgatac ggtgcaaatg cgcgaggcag
    42481 ccctgttcgg tggcctgtcc ggagacggcc tccagcgtga cggagagctg catggcggct
    42541 gcgtcgttgg tggcgagcac atagcgccgg ctgtccggtt tgacgccatc cgcttggacg
    42601 cgatagccgg tcatgtcgag actcacggcc caggtcttgt cgatgagggc gatgcttcgc
    42661 tgatgcggaa tctcctcggc gagaccggca ccggatgcca tgagagcata gcccagtgca
    42721 cttgcaagca actgtttcat tgccgatggc attcccgctc cctgtccgct ctttctgcca
    42781 gctgattgtg gcgtcactgt agtctaacgt cgaggtcttg cggaccaaag caaaagtaca
    42841 aaaccagcgc cctctatgct gacagcatca ttggttttgg atcggaaaca cgggttgatg
    42901 ctgtggcgtc gtgccacagc atcaggagag gactgtcgcc tttgacggca gcacggcaca
    42961 cctcggggag tgaccgtgtg gcgaatatct cgcgggccac catcaatcaa tggcggtatc
    43021 ggcgttgcat agtcctcgat aagaatgtat ccctatcctg ggaccaggca cgatgctgtg
    43081 aagagagagg tggcgatgcg cgaacgagac gtacaggcga tcgggacgag gcgaggcgct
    43141 cgtgtagggt ggccgacggt cttcgggatc tgtgctgtgg ccatgatggc acaagtatcc
    43201 tctgctcctg cggtggtgca cgtacttcct gatatgaccg tgacgcgtga cagtgggacc
    43261 gtcaccggtg ccaaggcggt tcgtgccgat cccacgctgc aggaagtgct ggcggcattc
    43321 gatcgtgcag aacgtgccct ggagaagcag gacctgtcct cgctgatgca gttttatgcg
    43381 ccgggctaca actatcacgg cttacacgtg gaggatgtcc agcgcatctg gggtgaagtg
    43441 ttcgagcact atcggacatt gtcctcgacg catctctttt ccgagatgaa gatcgtgcgt
    43501 gccgaggacg ggttacgcgt cgagttgacc tgcactggcg gcttgtatgg cgctgacgtg
    43561 caatcaggcg cgcgcatcac gctggatagc tggtttcagg aggtgcacta tctcgtgcgg
    43621 gacaggcagg gatggcggtt tctgggaaat cgaggtgatg caccgcgttc ggcgcccttc
    43681 tcctcatccc cgcaccatcc gctgttctga tcgagacggg ccaggcggtc aggctgcggc
    43741 cgccgaggcg gcagtggccg cggtgctgag cagctttttg acgctggcat gggccaacac
    43801 cacgtccgga gtgcgttgca gggcttcgta ataactccgt tcgaacccgt cgccttcttc
    43861 tgaagggcgc agcatgtggc gggcttccag cagaaggtct tgcgccgttt cgatggtcgt
    43921 gtcttcgtga tcttccagca cgacatcgat gcgaacgacg agatgcgaca aggggtgcag
    43981 ccaggcgaac cacgggtcat tcatcaccag ctgcaaaagc tgaccggccg aggagatgcg
    44041 cccatagatg cgttcatacg tcagctgttc ggagacgatg agagatttgt gcaggccgag
    44101 caagccgtga cgaaggtcct tcaggctggc acgaaggtta tccggaagcg gattcgaaga
    44161 cgaccaggag gaacgtgtca tagatcaccc accctacgca atccacagct tcaagcgacg
    44221 gccgttccta ccacaggaat gatgccccct tcagggccac tctccgtcct tcgtggatac
    44281 tgtatcggct ggtttgcgcc gggattgagt ccccgggatt gtgaaatcga cgaaactccc
    44341 cctcgaagcc gcgtgggcga gggcaggaac ggctgttttc tccgcaagtt gaagtgctta
    44401 ggattggggt tgggggaagg gggctatccc taaggagccg cccccgcagg gaagctgaaa
    44461 gagatcggaa cgtatggtcg aagcccgaca gcatagccag acccggtggt acgcacggtc
    44521 ccttgacgat ctcggccggg agttcggcgt cgatcaggcg ctagggctgg atgaagatga
    44581 agccgcgcgc cggcttaccg cccatggccc taatgaattg cctgaggctg caccgccttc
    44641 gccctggcat atgttgggtg cgcaattcag cagcctgatc atctgggtgc tgatcggcgc
    44701 cgctctcgtg tcgggtttgc tcggcgaatg ggtggacgcg tgcgccatct tggccatcgt
    44761 gctgctgaac gggttgctgg gattcgtnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    44821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    44881 nnnnnnnggg aaagggcgtg ccctgatcgt tgccaccggc agcggtaccg agctggggcg
    44941 tattgcgacg ctgatgacca cggtgcctgt cgagccaaca cctcttcagc ggcgcttgga
    45001 acagttcggc catgtgttgt tgtggttatc actggctatc gtggtcgtgg tgttcgggct
    45061 tggcttgtgg cggggggagc cgctgttcga gatgttcttg acggccgtga gtctggccgt
    45121 ggcggccatt ccagaagggc tgccggcgat tgtgacgacg acgctggccc tgggcgtgat
    45181 gcgtatggtg agccgccatg cgctgatccg ccgtctgccg gccgttgaaa ccctgggcgc
    45241 ggcgacggtg atctgtacgg acaaaaccgg caccttgacc aagaacgaaa tgacggtcac
    45301 ccggctggcc gtcgatgacg tggtctatga cgtgaccggg gagggatatg cgccggaggg
    45361 cacgattgtc gatggcgatg gccgcacggg agcgttgcga gcactgttgt ggagcgcagt
    45421 cttatgcaac ggatcctcgt tgcgggccgc agaaggcagc tggacggtgg tgggtgatcc
    45481 cacggagggg gccttgttgg ttgcgggcgg caagggcgga tggcggaaag aagcactcga
    45541 acgcgcgcac cctctggtgg gagaaatccc cttcgactcg gaacgcaaga tgatgacgat
    45601 gattcgccga tcggaagggc gtgccgtggc ctacgtgaag ggtgccccgg atatcctgct
    45661 ggagcgatgc gattcgtata tgacgaagtc gggggaagtc gcccccctgt ctgattcaat
    45721 gcgccgttcg atggtatcga tcaatcagca attcgctcag caagccctgc gggttgtcgc
    45781 attggcgcaa cgcgtactcg atccggatcc ggcgacattc gagtcgaaag gcattgagca
    45841 gcaattggtg ttcctcgggt tggctgcgat gaaagatcct ttacggccgg aagcgaaaca
    45901 agcggttgag cgatgccggt ccgcaggcat cacgaccgtg atgattaccg gggatcacaa
    45961 ggagacggca ttggctatcg gacgcgaggc ggggttcgca tccggctcga cgcaggccct
    46021 ctccggcctg gaactgaacg gattgactga tgcggagctg tcgtcccggg tgcgtgacgt
    46081 gtgtgtctat gcgcgcgtgt cggccgaaca caagctgcgc atcgtcaggg cctggcgcgc
    46141 gcaaggcgca gtcgtggcga tgaccggcga cggcgtgaat gatgcccctg cggtgcggga
    46201 agcggatatc gggatcgcca tgggcatgac aggaacggat gtgacgaaag acgcgtcgga
    46261 catggtcgta accgacgata actttgcgtc catcgccgcg gcggtcgagg aaggccggag
    46321 catctacgag aacattcgca aagccgtgca ctatttgctg tcgtgcaacc tgagtgaagt
    46381 gctggtgatg ctgggcagca cgttgttagg ctggccgttg ccgctgctgc ctatccacat
    46441 tctctggatc aatctggtca ccgacggatt tcctgcgctc gcgttagccg tggatccgaa
    46501 agatcccgat gtgatgaagc gcccaccgcg cgaccccaaa gcgccgctgc tggatcgcca
    46561 acggttcgtg accgtgtgcg ttcaaggcgc ggtgatggcg gcggcgacct tggcggtgtt
    46621 cgggattgcc ctggtgatca tgaaggacga ggtcacgttt gcgcgcacca tgacctttac
    46681 gacgctggtg ctggttcagt tcctccatgc gtttacctgt cgtcacgacc ggttctcgct
    46741 gtttcagatt ggtatcacca ccaatcggat gctggtggcc gccgtcctca tctcagccct
    46801 tctgcaggct gggattctgt tgagtccatg gggacaggat atctttcgag tcgttccgct
    46861 acgactcgat gactggtggt tggtcgcggc gtgcggaatg ctgccgttcg tggtgatgga
    46921 actgtggaag gcctggagtc gagtgcgaaa cggggccgcg cgcacgtcta cggcgtgagt
    46981 ttgggcgctg cccagatcgt ggtaagcggg gaggcctgcc ggctgagccc aaccggttgc
    47041 gctccataca tgtccgtgat cgtccgcagc agcccgtagt gattcgtctg ctcatggtag
    47101 cgtcctgggc gcaccatcgg acccacgaga atcgtgggaa tatggttgtc ggattttccg
    47161 ttgtcctcgt cccacgtaat gatcaacagg ctgttgtggg tctgcgccca gtctacgtag
    47221 cgttcgaggc ggacctggag ccagtgatct ccgcgttgaa tgcggtcggg atcgttgccg
    47281 tcgtgcatat cgttttgttg attgggcaca atgatgctga cggttggcaa ggtgctcaaa
    47341 tccgtcggaa agtcggtcag cgggcggttt tgcgcagccg ggacggtgtt gacaggagac
    47401 gcttgccagt tcacccaggg gttatgtttc cgcgcataag cgcctgcaat gcaatcgacg
    47461 gcccccacgg cggggagatc ttcggagtaa ccaataaacg actgtccggc ctgcttcaga
    47521 gtgctggaca ggttcggagc cgtcagcggg gtcggacaga cgttcccatt gacgccttca
    47581 atggtgccgg caaacagcgc gatgtagttc ggctggctcg gatgggttac ggcgtaggaa
    47641 ttggtcagca gagcgccttt acgtgccagc gcgtttaagt atggggcggc cggagagtcg
    47701 ataatctggc cgaaggcatg attctcttcg atcacgatca ccacatggtc cggcttgggc
    47761 aagggcgaat gggctgaacc gggggtggtc caggagagga agagtgcggt gaagacgagt
    47821 gcgaagactg acctgttcat cagggtctcc tgatcgatta caccgggagt tcgctgagtc
    47881 gtagtgtgta gaggtagtgg tacagcccct gttgctccag gagcgccgca tgggtaccgg
    47941 attcgacgat cttgcctttg ttcagtacca gaatgcggtc agcgcgttga atcgtgctga
    48001 gtcgatgggc cacgacgaag gtggtgcggt tgaccatgag ccgttccagg gcttcctgaa
    48061 ccagccgctc cgattcggta tccagcgccg aggtggcctc gtcgagcagc agaatccggg
    48121 ggttcttgag aatcgctcgg gcgatagcga cgcgttgccg ttgaccaccg gacaagttga
    48181 tgcctttttc gccgacgatc gtctgatagc cgtcaggaaa tcccacgatg aactcatggg
    48241 catgggctgc tgtgctggca gcaatgattt cctcctcggt ggcatcctcg cgtccatagc
    48301 gaatgttatc gcggatcggg ccgccgaata agatcgtgtc ctgaggcacg agcgcgattt
    48361 gccggtacag gctgtcgagc cgcacgttct tgacgtcatg accgtcgatg gtgagccgtc
    48421 ccgaggtcgg atcatagaat cgatgcaaga ggttcatgat cgtcgttttg ccggagccgg
    48481 tggggcccac gatcgcaatg agttcaccgg gcttggcttc gaacgacacg tccgagagca
    48541 cgggttgccg ggggtcgtag gcgaagctca gattttccgc gcgcacgtgc ccgcgaaccg
    48601 ccggcaattc aatcgcgcca ggcgcgtccg caatttcggc atgggtatca aggatttcga
    48661 acacgcgttg catcgcgcct tgggcttctt tgatttgcgc aaagacgcgg gctgccgatc
    48721 cgaacggtcc gatcagaatg ccggcaaaga gcacgaacgc aaacaggtcg ccgggggaga
    48781 ctgagccgtc gatgacctgg cggccgccgt accacaagac gagggcggcg gcggcaaagg
    48841 tgacgaagat gattgtcggc acgaaccagg ccatgatggt ggcacggcgc agtgacagct
    48901 ccatcgcgga ctggacctga gtcacgaacc gttcttcttc ccgtttcgtt tggacgaagg
    48961 atttcacgac gcggatccct gcgatgactt cttcgaccag cgtgctgacg gtagccgttt
    49021 ggtcctggat tttggtagac agcgcccgga gccgccgccc gaacagtttg gccacgacga
    49081 ccagcatcgg gagcagcacc agaatgagca ggcagagttg ccagttcatg gcgaacagga
    49141 agcccgcgcc gccgatgaag gtgacgattt gtttggcggc gtcgatgggt gtatcggtga
    49201 cgacattttg gatcacggtg acatcgttca tgaggcggga catcaattcg ccggttcggc
    49261 gcttcgagaa gaagttgact gacagcgtct cgagatgtgc gaagagatgg atccggaaat
    49321 cggccatcac ccgttgggag acccaggccg tgaggtaact gtgccccatc gaacataacc
    49381 cctggatcaa gaccaagccc aacaagagca ggatcatgtt tgtcatgcgc ggggcatcgt
    49441 gctggaccgt gatgacgtcc cacagagtgc cgcctaagcg aaggagggca aggttgatgg
    49501 cagcaaccgc catgaccatg acggcggcag cgatcatccg ggggacgtag ggcttgagga
    49561 aggggtagaa gcgcttgaac gagaacatcg gtgttacgac aattgtttca gggaggcagg
    49621 cgcgtagcgt atcaccggtg gtcgcggcgg tacgaagacg acatgacctt cgtgatgagg
    49681 tgagagcgct agagctgagc gattgactcg atcaggttct tgttgatcgc cacaaagtcc
    49741 gatcgatcct tgtcattgat caaaacgtca gtcaggctga taaacagccg ctgctcttca
    49801 ttgatcgcat cggacacacg attacgcatg ggcgggatga ggaaatcccc gacgt
//
LOCUS       DAOQPD010000021        44541 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_328_length_44541_cov_20.320415, whole genome shotgun sequence.
ACCESSION   DAOQPD010000021 DAOQPD010000000
VERSION     DAOQPD010000021.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 44541)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 44541)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44541
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_328_length_44541_cov_20.320415"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..376
                     /locus_tag="PK063_07110"
     CDS             <1..376
                     /locus_tag="PK063_07110"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96852.1"
                     /translation="RLPFSYFHVFSYSSRPGTPAARLEPQTPGTIIRQRSKTLAELSR
                     TKALAFYQRQIGRTVSVLFEQGEHDGFRTGTTANFTRVAVPADAVAAGSIHPVTITGI
                     MDGLAYGHLASPSVEPTYRPLL"
     gene            373..>1376
                     /gene="miaB"
                     /locus_tag="PK063_07115"
     CDS             373..>1376
                     /gene="miaB"
                     /locus_tag="PK063_07115"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: protein motif:HMM:TIGR00089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HMZ96853.1"
                     /translation="MTQPNKPHTVHIETFGCQMNEYDSELVRTLLRKAGFEFTEDRER
                     ADVMLMNTCAIRENAHNKVYGHLAELKAVKEQRPLVVGVLGCMAQNLKEELTEKQPLV
                     DVLVGPDGYRQLPGLLTNALNAEEQGLSRRGLAVDLSEYETYDDILPERDGGCNAWIA
                     IMRGCDNFCSFCVVPYTRGRERSRDPQGILREVEVSVEAGHTQITLLGQNVNSYRYDD
                     WDFARLILAVAEVPGVQRVRFTSPHPKDFPAALLDAVAGHPNICKHIHLPLQSGNDRI
                     LELMNRTYSRKEYLDLATTIRRRHPGIALTTDIICGFCSETEEEFLDTFRVVEDVQYH
                     S"
     assembly_gap    1377..1476
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            2001..2132
                     /locus_tag="PK063_07120"
     CDS             2001..2132
                     /locus_tag="PK063_07120"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96854.1"
                     /translation="MKKDIIQTHVEEAPKGISLETIIAVGVFGWMALGVVMMGLGIW"
     gene            2219..3256
                     /locus_tag="PK063_07125"
     CDS             2219..3256
                     /locus_tag="PK063_07125"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96855.1"
                     /translation="MLIHGSHSFLMHRLNSGILGLTLMGALASGCSSTAASVQQPAAM
                     QPQGSVRLEEVADWEFEASHPSSIDAATLDSLLRAVVIAEAQTDMSNLPVDGSKPMTV
                     FSDEDVRYLAPLLAQALSQAQPEYVVAFRLSSSAGSGSEPTAGTLYVKNDRLYLTLSE
                     HHGSLAKTESTWLGSGRAARIVSVMPASAGQLEQALPAVIQGRQQMKSLAIDYHQFAK
                     KPEPAPMTAATTAPAPQPVQALSVRNVPAVAPDQPAKQQSAPAPVMDKVASNQAPAED
                     ERLNETLQELQDTKDAMARKDAKISALRRDLESMRMQLETKDKELRAVKNTQQQQPKR
                     ETRNKAELTVR"
     gene            complement(3272..3988)
                     /locus_tag="PK063_07130"
     CDS             complement(3272..3988)
                     /locus_tag="PK063_07130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HMZ96856.1"
                     /translation="MKVVLDIETVQAPREEWARIAGRQLTSGEVTFAESGGDLFAVGE
                     AEAQQRLDDELYEKSSFDGTFSKIVCIGLLEFTDTLEPRGAISWYGGNEQALLRAFWS
                     HLGQSRPSLFITHNGLNFDLPFIKKRSIIQQVKPSMEINLAKFRAEPVYDTMAIWSNW
                     DNRGWVKLDVLARALNVESKSGSGSQVAQMWADGQGKEIALYCLQDTYVTYGCYCRMN
                     FRPPISREIVLLKPELVDVG"
     gene            complement(3995..4423)
                     /gene="mutT"
                     /locus_tag="PK063_07135"
     CDS             complement(3995..4423)
                     /gene="mutT"
                     /locus_tag="PK063_07135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase MutT"
                     /protein_id="HMZ96857.1"
                     /translation="MMVQRLDTGKVAMQVIEVAAGIIAHEGRYLIARRKAGAHLGGLW
                     EFPGGKRETGETLEECLHRELWEELQVRVSALTPFQIVRHEYPEKVVVLHFFRCRIEA
                     GVAIAIDCAELRWVYPHEMASFEFPPADQPVIAALQQRKV"
     gene            complement(4471..5190)
                     /locus_tag="PK063_07140"
     CDS             complement(4471..5190)
                     /locus_tag="PK063_07140"
                     /EC_number="3.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000701 - purine-specific mismatch base
                     pair DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HMZ96858.1"
                     /translation="MPTKPRTQKPSRRKKQTSTPALPLARGQKQRFQNRLLKWYKEYG
                     RDLPWRKTSDPYHILVSEVMLQQTQVDRVIPKYHEFLERYPSFAELADAPVAEVKQTW
                     YPLGYNIRPERLHSIARETVARYGGQLPSDADELLSFKGIGRYTAGAIRSFAFNEDAP
                     ILDTNVIRVLHRVFIAEGDPKGQKALLWELSEALIPRGKGYDFNQAIMDFGATICTAR
                     NPYCLLCPMKPLCKTYPFGEK"
     gene            complement(5343..5708)
                     /locus_tag="PK063_07145"
     CDS             complement(5343..5708)
                     /locus_tag="PK063_07145"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96859.1"
                     /translation="MKASFSIYALAAIGMLGAAVAFANPALLPQHPGYPMGKATDPVN
                     GQALANDPGRANGGGESALAGSAAFDDRHVSQKLSINDQNQRLLEKPGAGILPKVQGP
                     NIVIDPPVKEGTKVQASPQ"
     gene            6266..6589
                     /locus_tag="PK063_07150"
     CDS             6266..6589
                     /locus_tag="PK063_07150"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ96860.1"
                     /translation="MSMTVHYRVSLSADSTTTGEGRLLDLSLEGCRIECDRHLPVNTY
                     LSLRLQISPNEMPILVDLAAVRWTRGTNCGVHFLSVQPLQSARLQTFLAAASPRKEPP
                     TPGAG"
     assembly_gap    6634..6733
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(6814..7533)
                     /locus_tag="PK063_07155"
     CDS             complement(6814..7533)
                     /locus_tag="PK063_07155"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024950.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HMZ96861.1"
                     /translation="MKRLDGKVAVVTGSSSGIGKAIALRFAQEGATVVVAARRFYKCE
                     ETVAQIESAGGRAVALQTDIADESQVEQLMAETIRRYQRLDILVNNAGIFGGRRLAET
                     STEAFDEVMRTNVRGTFFCCRAAFGLMKKQGGGTIINMSSVAGVQAWSGTGTYSASKH
                     AIMALTKSLADEGRAYRIKVSALCPGGVADELVDATPEARAASEKIDPFDIAEAALYL
                     ASLGPQAVVHQLVVDRLGADW"
     gene            complement(7663..7956)
                     /locus_tag="PK063_07160"
     CDS             complement(7663..7956)
                     /locus_tag="PK063_07160"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96862.1"
                     /translation="MSPLNRFRSSNDTKDIRIVGCDVHLTFHQGGGEQWYVEATFRCG
                     VGEKRREESVDSGPCATREEAEQIVLGRVGHMLGHNVDSHTSPVKNPTEKNPQ"
     gene            complement(8066..11596)
                     /locus_tag="PK063_07165"
     CDS             complement(8066..11596)
                     /locus_tag="PK063_07165"
                     /inference="COORDINATES: protein motif:HMM:NF024904.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HMZ96863.1"
                     /translation="MKLLKLLLQAYGPFTGKVLDFSTGPANLHVIYGPNEAGKSSALR
                     AMMDLRFGIPVRSADDFLHAAGDLRIGGIFAAINGEAIGFVRRKGKGTTLARLNVLTE
                     QPDQSLVMEPGHERGLTGGLERVEFEAMFGLTHARLREGGQVLLRGEGDLGSALFEAS
                     AGTSGIATLLAALETDAKKLYSPHGRAQNAVINEARRRLDEQRQAWREAQTKPAEWQS
                     LYRAHEAAAATLSDVSMTLERLRRRENELIELRTVGPLLRTHDAATALLASFAGVPDL
                     PEQAREARLAALQELNHAEHSLREAEVEAERCARALGALTLEPLVLEHAAAIERFVSG
                     VAAAARYRIEVQQQDAVIAALDADLGLAIARLAPGREVRDVLHAVPSAADRLVLDDHL
                     MQVSRLEDRLEHIRQRATALDQALASSHQESWLPIDPGSRQQLMTAVRHAQSLGDVVR
                     RQKELDQQRREMDLLLEQALADVGLASDQALRRAQPLLDAQIARTRQELNDLDEQIRK
                     LRDEQELVGRDLDGQRLRLRQLAAEGEIVTAETLRQARAKRDDRWKAIREAYIDRTQT
                     LDQLALGFDTARATPEMFEAALSEADRQADLLRADAKRAAGLEECTGRIEQMEGRRSD
                     IERQIARLSAGRGATLDAWAQRLKDAGLPDLDPEPLREWQGRRADALQIAERVAGLRA
                     ASDRLQEETNNAVAGVRAALLKLGHPVSEANPVDVTLLPSLIEQAVAYDSKAVEAEAA
                     HNAKEQAATVQRIERQQLDRSMAEMGAELRRHQSALQAWHARLFLASDTIPDAIKVRL
                     DELDGAARQAAALGEAKQRRAQVQAILDDLAAQSKDVAAVLDIPAPQMVEDFADRLRG
                     RLAAAKAAEQEQATLLRDQRKAEEKRRGAASDRAAQQTILARLCAVAGVTGLEDLPQR
                     EEAASRKREASASHTHVRQQIAAASSLSVEELRQRLSGRDAVTIETEREQCRSEITRC
                     EEEQAAARRAEEQARLALNAIDSSDRAARAREAMESAAARYRSAIRPWARLKLARALL
                     QEALNRFRERAQAPMITKASAYFALMTDGDYERLISDDTGGQPRLCALRQGGTSVAVE
                     EMSEGTADQLYLALRLAALDIRREAHPQMPLVLDDALITSDDRRVAHILRALALFAEE
                     GQVLIFTHHRHLLDVARAAIGEQAFVSHHL"
     gene            complement(11593..12852)
                     /locus_tag="PK063_07170"
     CDS             complement(11593..12852)
                     /locus_tag="PK063_07170"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HMZ96864.1"
                     /translation="MRFIHAADLHIDSPLRGLDRYDGAPVERLRTATRSAFERLIDTA
                     ISEHVDFLLLAGDIYDCDWQDFHTGLFFRGQMVRLEREGIRVFIVQGNHDAQGVISKQ
                     LVLPPNVTVFSSRAAHTIRLDDRSVAIHGRSFPERAVDEDLVPSYPPPVPGFFNIGLL
                     HTSLTGRAGHDTYAPTDLPTLNHKGYDYWALGHVHAREVIAERPHIVFPGNLQGRHAK
                     ETGPKGCELVTVEAGRIESEFVALDVVRWNQLIVSLDGVQRLEALGEAFRHALEPVLI
                     GAMDRLHAVRVTLTGSTELHRLEASQPGTLAAAMYGAAQDIGEAEVWIEQVRLDLTTP
                     LDRVQTAQRQDAVGELVRLVDSVAGDESELQRWAQVELGDLLGSLPQEVAAGDVPKLD
                     DRVELTQLLMEAEATVLARLTDLGAEA"
     gene            13305..13892
                     /locus_tag="PK063_07175"
     CDS             13305..13892
                     /locus_tag="PK063_07175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HMZ96865.1"
                     /translation="MSLESTPSTALSPEAIAQLVQGHKQFLAFLERRVESRAVAEDIL
                     QSAFARGLERGAGVDEEKVVAWFYRVLRNAVIDHYRQRSSAERAVEAWTREFPDVQEP
                     AAELRQEICQCVSGLLETLKPEYREALQIVDLQEGKLKDLAQQSGITAENAAVRVHRA
                     RAALRRQIEKACGTCSVHGCLDCSCEASGGSTCGA"
     assembly_gap    13906..14005
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <14006..14339
                     /locus_tag="PK063_07180"
     CDS             <14006..14339
                     /locus_tag="PK063_07180"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96866.1"
                     /translation="VPARHPADRLAGHEDNAAADIRTLFLHLRQLPPYARITMTEPTM
                     RLSNLSLAELKSLVEGLVDDRLRALLGDPDLGAPLGESVRERLKQSLSSTERLSGDEV
                     ADKLGLRW"
     gene            14341..14616
                     /locus_tag="PK063_07185"
     CDS             14341..14616
                     /locus_tag="PK063_07185"
                     /inference="COORDINATES: protein motif:HMM:NF016876.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HMZ96867.1"
                     /translation="MPWFRLAFRPDVITDLRAADSSMAQRLFDKTKWLASNVENLRHE
                     PVAADLPGIHKYAVGDWRIFYSIDRSEQMVDIHYIQHRPQAGRTPGA"
     gene            14619..14924
                     /locus_tag="PK063_07190"
     CDS             14619..14924
                     /locus_tag="PK063_07190"
                     /inference="COORDINATES: protein motif:HMM:NF013671.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HMZ96868.1"
                     /translation="MLTLTQKAVDRLRALLLEHPEDPVVRIAVRDVNEQRLSLAITLE
                     AAVREEDVVEQIEGLTIAFDRSSAHRTGGMTVDYQAGRFSFAHPPANELGLIMPGRN"
     gene            complement(14993..15535)
                     /locus_tag="PK063_07195"
     CDS             complement(14993..15535)
                     /locus_tag="PK063_07195"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HMZ96869.1"
                     /translation="MKFCSECGAGLSKKIPPGDNLPRFVCETCQVVHYINPKIVAGCI
                     PEWEDKILLCRRAIEPRIGHWTFPAGFMEIGESTEQAAVRETFEEAHAEVEITSLYAV
                     LSLPRISQVHMIFRGTMRTPEFKPGTESLDVQLFTLDAIPWDDLAFPVIQDALERYVA
                     DVARGTFTMHFGSVFPRMKS"
     gene            15570..16763
                     /locus_tag="PK063_07200"
     CDS             15570..16763
                     /locus_tag="PK063_07200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="THUMP domain-containing protein"
                     /protein_id="HMZ96870.1"
                     /translation="MDSTIQAFFAPCPRGLEAVLAEELTMLGATAVKATAGGVAFRGT
                     LALCYRVNLQSRIASRILLRIAEGAYRDEHDVYDAAYAIRWQDWFTPQQRIKVKVSAH
                     RCPLKSLDFVTLRVKDAVCDRFQYARGKRPSVDTHAPDILIAVYLDGTQCTFYLDTSG
                     DPLFKRGWRKSSGEAPIRENLAAGILRLSKWTPDVLLYDPMCGSGTFVVEAALMAGRI
                     APGIGRGFAFEKLLSCDAPMLNDLRAELQAAEIPVKPGLIHAADQSAQAITSIRANLA
                     LAGLTEAVTLQQGDVLQLPAPAEAGLLVTNPPYGHRMGDDETLKTFYPQFGDHLKKHF
                     CGWTVQIFTADMKLPGLLRLAPSRRVPLFNGAIECRLFEFRMVAGSLRKPKPPAQSSP
                     GHGHH"
     gene            16877..18403
                     /locus_tag="PK063_07205"
     CDS             16877..18403
                     /locus_tag="PK063_07205"
                     /EC_number="2.4.1.15"
                     /inference="COORDINATES: protein motif:HMM:NF013173.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003825 - alpha,alpha-trehalose-phosphate
                     synthase (UDP-forming) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose-6-phosphate synthase"
                     /protein_id="HMZ96871.1"
                     /translation="MSAAHAPLEAPQQEHDLSLSRLIVVSNREPYEHRLVKDHLIWER
                     TSGGLISALDPMMRRLGGTWIAWGSGKADRDVVDEDMVVEVPPDAPTYRLRRVWLENG
                     EVKGGYQGYANQVLWPLCHLTLDRVAYRKAFWHAYQAMNARFADVVLGELAEKPGFVW
                     VHDFHLALLPGLIKASLPNQPVAIFWHTPWPGPDAFRILPERRELLESLLAADLVMFQ
                     TESFLHCFLECAKEFLGTDVLSDEHHIDYKGHCTRLVVRPISINYQSWAERAQSPQVT
                     RAMDVLRNLHIFQPTVRIGLGVDRLDYTKGLLKRLWAIDAFFQQYPQYRGHFTFIQIA
                     VPTRGDVEAYRSYRELIRETVNEINMRYGTISHPGSPQASRWRPIEFREGRIGMDTLA
                     AYYRMADLALVSSVYDGMNLVAKEYVASQVEEKGVLLVSHLAGAAEELTDAVVINPYD
                     PEGVADSIRQALEMPFGERRERMRRMRAYLEAHDIRAWADDCLRDAGILPQQDSPALE
                     "
     gene            18324..20453
                     /locus_tag="PK063_07210"
     CDS             18324..20453
                     /locus_tag="PK063_07210"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96872.1"
                     /translation="MTFAPGLMTACATQESFHSRTVPPLNNRRLPATTDPKIPLRRHL
                     PLFLFLSLSMLLNGCTQLSKLFAVTPSPDQQVDRHQQAIVSRLAPVIEAELQDNLNVM
                     LPTVRKSLADQTNKVAKFKRDLVLRSLSDPWAGLTSIEQTSLVAATAAESGIEELPAI
                     IDILEEGMERSGAPFKPLNFPATLAPEDILGFIMEALEDAHQDREQALRHLSPQDRDF
                     LFTQARPLAEQFLPQIIPPARLAEAEAAGRYAALLMQQVDYASLIAAAQRLARLGNRK
                     LLQQLDIALHHRKPVTQTVPGITGDLLLVQQTSYGLLVIGGHGPNTYDLDKGAALIID
                     LGGNDTYRGLIGASPNSDLGNSVVIDLSGNDLYQPAPLGLATGRAGVGILIDHSGDDT
                     YRLAPGSGGAGFAGLGILYDGEGQDVYEGSRFTQGAAFGGLGLLVDRAGDDRYTSFGY
                     ALGFGGPLGVGALIDVSGNDSYECGGKYPSAYNEADAPHARPQDPAFQYDCFGLGTGA
                     GLRIYSKQPAQRAQSLAGGWGLLVDLAGRDRYRSANFSQGHGYFFGLGVKLDLAGDDE
                     HQAARYGIGTAAHFGVGLSLDYQGKDRYGSKGPFYNGGTAWDGSVALAVDGGPDSDLY
                     DLPASTGLGMADLGGLGLFIEEGGADQYFIGRGLGQGADTSIGAFFDLEGRDDYTSVP
                     LPNGDARPERLNRKTYLENTGSLFVDR"
     gene            20591..22987
                     /gene="lon"
                     /locus_tag="PK063_07215"
     CDS             20591..22987
                     /gene="lon"
                     /locus_tag="PK063_07215"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HMZ96873.1"
                     /translation="MTDANAPILTNLPILPLKRTVLFPGTMMPLTVGRDRSIAAVEAA
                     LKTEDKTLLVVAQRDAQTDQPTLEDLYTIGTKAVIKQTARTPEGHYNILIQGLERFVL
                     LKLDQVDPYLQARVKQLPPPSERSTEVEALHRAILDIITELPKLIQTPGVHEAVAALG
                     TEEDPVVLAYRIASLLNLTLDGEQQLLEASTRADLLRGLYAALSREVQILQLRDKITS
                     EAREKLGKTQREYLLREQLKTIQQELGESNGEEDEVAALRKKVQDADLPEHVRKETDR
                     ELTRLAKTPSASPEHQVIRSYLELVLELPWNKSSEEGLDLAHVRKILNEDHYGIKEVK
                     ERIVEHLAVLKLNPSAKAPILCLVGPPGVGKTSLGQSIAKSMGRTFERFSLGGLHDEG
                     ELRGHRRTYVGALPGRIIQAMRRAGVNNPVIMLDEVDKLGRDFRGDPAAALLEILDPA
                     QNHTFRDHYLDLPFDLSKVFFITTANTLETLSQPLLDRMEIIRVNGYSEREKREIALR
                     YLWPRRLKEAGLKAEEVNLPDSVLDHIIGRYTRESGVRQLEQMLGRITRKVAVTFADR
                     PSDSPAAPVEITQSLLDEWLGQERFQPEEARKNLPAGVATGMAWTPTGGDVLYIETTL
                     LPGSHELTLTGQLGDVMQESARAARSYLWSHAESMGLDISRFKRNGVHIHVPSGAIPK
                     DGPSAGITMATALASAYVGKPVRSDTAMTGEISLTGLVLPVGGIKEKVLAAHRAGIRR
                     IILPKANEKDLKEVPQEVRDELTVIPVERIEEVLPAAFNQDAASSPEKHEPMATSTAS
                     "
     gene            23170..23589
                     /gene="msrB"
                     /locus_tag="PK063_07220"
     CDS             23170..23589
                     /gene="msrB"
                     /locus_tag="PK063_07220"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HMZ96874.1"
                     /translation="MPSNIEIGPIVKVNKTDDEWKKLLPAAAYRVLRHEDTERAFTSP
                     LHDNHQAGIYHCAGCDLAAYSSDHKFDSGTGWPSFWQPVDPKVVETRTDTKFFMTRVE
                     VHCARCGGHQGHIFEDGPKPTGLRYCINGVSLKFVPA"
     gene            23716..24879
                     /locus_tag="PK063_07225"
     CDS             23716..24879
                     /locus_tag="PK063_07225"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96875.1"
                     /translation="MASLPSLRSTMAALWLGVTLLGCSQSSDVISNNLNACLIVTEAE
                     VEFAIGTPVTPGLRQNDRQCLYQAKRNPQETVVVELNAGPDGDRKTLFQDQRSKAGNQ
                     PVPGVGDGAFTLRSPIGGIQLTFLKSDALVTLSLTSPKQANPQAAVTNLAKVAANRLG
                     APIRTTAAAAEPGITGTPSLWAGEWYGCMPVGMMYGKGHLSLNERGTWSMTTAVVMPG
                     TIIADRGRWEAESYQEILHGTYKVAGSDRFSTTGILSVTWDKLAKNQGPTKFDPLLWQ
                     SFTAIPRKVNVKRLPAVEPSLVGTWEGSSKFVDRQEDFVWTITAANVSEFFKATSQTG
                     RIEQEQDRFRLVVPQSKTPPLSVRVLAQDKMELTDTSGTVSQWNRNEKLLSRC"
     gene            24970..25377
                     /locus_tag="PK063_07230"
     CDS             24970..25377
                     /locus_tag="PK063_07230"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96876.1"
                     /translation="MRTWLIAIIFLAGPLLPAAGAPVGAAADRPTPKASELLDEIIPK
                     ELFRHLYSEALSTLHEYIEMEGKLPGESSTHQQGGEFRLKLFPHGKSRSQEHLSAEGS
                     FRVAPEADQPEFTLRFKSFKKASPPARTNDDVI"
     gene            25998..26159
                     /locus_tag="PK063_07235"
     CDS             25998..26159
                     /locus_tag="PK063_07235"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96877.1"
                     /translation="MEVEIIGAGTMIALVWLIAWSMAGESESERRRITSAPGTFDTAS
                     GETRVRHAA"
     gene            complement(26279..>26529)
                     /locus_tag="PK063_07240"
     CDS             complement(26279..>26529)
                     /locus_tag="PK063_07240"
                     /inference="COORDINATES: protein motif:HMM:NF021915.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HMZ96878.1"
                     /translation="ALVKQYQALFEIEGIDLQFTEAAIKAVARRAAVMKTGARALRTI
                     LEEVMLDLMYDVPALSGVKSVVITEEVIAGIGQPKILA"
     assembly_gap    26530..26629
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<26630..27717)
                     /gene="clpX"
                     /locus_tag="PK063_07245"
     CDS             complement(<26630..27717)
                     /gene="clpX"
                     /locus_tag="PK063_07245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014961336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HMZ96879.1"
                     /translation="MFWDTRHSTQKPDRRCSFCGKPQDAGRTLVTNSEPFACTSCRNP
                     AAVSICEECIQRCSLSLAKNKTPGSQSSVSPLPLVIPKPTDIKAKLDEYVIGQDRAKK
                     VLSVAVHNHYKRIVNRERLKHVDLEKGNILMIGSTGTGKTLLSQTLARILHVPFTIAD
                     ATALTEAGYVGEDVENVVLKLLQNCDYDVARAETGIIYIDEIDKISRKSENPSLTRDV
                     SGEGVQQALLKLVEGTVCNVPPKGGRKHPEQDYIRVDTTNILFIAGGAFVGLDAMIAQ
                     RTMPKRLGFGAIAPAGELEGHSEVLRCVQSEDLLKFGLIPEFVGRFPVLTTLADLDVP
                     ALIRVLSEPRNALVKQYQALFEIEGIDL"
     gene            complement(27861..28610)
                     /locus_tag="PK063_07250"
     CDS             complement(27861..28610)
                     /locus_tag="PK063_07250"
                     /inference="COORDINATES: protein motif:HMM:NF024895.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HMZ96880.1"
                     /translation="MKSRFWSLGVVVLAGVLLQVYPALLLAADPAANAVKSPSASAEG
                     KAEETKSELYISLYMQGSRPLNRPARLQEDPFTNTDVQGGLGGGLKIGFFPAFAGRYV
                     GLEAELSGLDGKVNAPTATSGGVTRSANFRLQSINAMANLLLRYPGDVIQPYIGIGAG
                     LSGGFARDLNLQHSTIGTVHENAADGAFAYQFLGGVRANITDRLFLFTEYKYFVANYQ
                     WESEFTNGSRGPSFTLNYRTHIIAGGFGVTF"
     gene            complement(28770..29360)
                     /locus_tag="PK063_07255"
     CDS             complement(28770..29360)
                     /locus_tag="PK063_07255"
                     /inference="COORDINATES: protein motif:HMM:NF013488.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HMZ96881.1"
                     /translation="MTSRKTSCRVYSDFNCPFCYAMHERLYALGFLEQISWHGVQHAP
                     HLPQPMATWAGHLHAELKQEVKMVRRLAPELPISVPAGKPNTRLAITVAARALREDTR
                     RAGEFIRSLYRLFWVDGLDLSNERLLRLEAERQGFVGTALFGSTAPAVESMLGEWRDR
                     WEETEHQGVPLLQRADGQVLVGLVPPETLTQFLASS"
     gene            complement(29357..30184)
                     /locus_tag="PK063_07260"
     CDS             complement(29357..30184)
                     /locus_tag="PK063_07260"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016812 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in cyclic amides
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HMZ96882.1"
                     /translation="MVIKPRHLRWLGLSALTLCVVMHVSAVSGSHAAEIGPRVLDLTY
                     PFDETTQVWPSNPPFHRDSTQRGGTTTEAWYATGQVALSEHAGTHMDAPIHFAQGQAG
                     IDGIPVEQLMGPAVVIDVRAAAADDRDYRLSLADIHRWEAAHGTIPTGAIVMMLTGWG
                     AYWNDRQRYFGSATPEIPTTLHFPGFSKEVAEFLVRERHISGIGIDTASIDYGPSQDF
                     VVHRIVNAAGLYGLENVAGLAEVPASGARLVALPMKIAGGTGAPVRIIAILPSRDGK"
     gene            30284..31432
                     /locus_tag="PK063_07265"
     CDS             30284..31432
                     /locus_tag="PK063_07265"
                     /inference="COORDINATES: protein motif:HMM:NF012246.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RuBisCO large subunit C-terminal-like
                     domain-containing protein"
                     /protein_id="HMZ96883.1"
                     /translation="MSDQQLHFSGQRFSVEYHIQGTKEEACRRAAVLCIDQTVEAADH
                     VIPSGVIRDQLLGQMLSIDRVGDGVHRATLTFPIELLDGTMGTLQHMSFGMAGLQSRV
                     RLANLSLPDEAIAQMAGPRFGSLKLRALLEVPVRPLVCAVLKPLGLSARALASLAYEF
                     ALGEVDLIKDDQSLGDHPFCRFEERVTLCAEAIAKASRQTGRRCLYAPHVSGPWPTLL
                     DRASLAQNAGAGALLLCPGLTGFDALGTLARLPFPSLPLIAHPDFQGSHFVNSATGIA
                     PAVLFGLFPRLAGADVSIYPTFGLEYPISQEDCRGIAACCRNSLGACAPIFPTAAGRM
                     EASRIHEMVAFYGTDVVFVLGSDLRRDPTRIRSACQEFIQLLEAEVAP"
     gene            31676..33016
                     /locus_tag="PK063_07270"
     CDS             31676..33016
                     /locus_tag="PK063_07270"
                     /inference="COORDINATES: protein motif:HMM:NF023299.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3391 domain-containing protein"
                     /protein_id="HMZ96884.1"
                     /translation="MALAKTSDDSRKLDKSDTLVLSPERLRVGMYVDLNCGWFRHPFP
                     RRSFKLSSASQIATIKGLGLTTVLVYPRESDPDPDAEGTLLETDPASTATVEPDTGSA
                     PAAAAADTNPPPSDEELPTHGDYHQAVELASETYRQMLGTSKDMMDALTSGSEEGMRS
                     AETMIGGISTLLTHTQAAGTVASAFDPEEIGDAGVLHSLNVATLSMMVAQQFDIDQDA
                     LQMIGLAGLLLDIGERRIPRHILDTRARRSETEHVKYQLHPYLGVEMLRGFPGIPEEV
                     LDVIRSHHERLDGSGYPEKLKGDQISFPTRIVSAVDHYDTLVNSLYAEEALSPAEALA
                     TMYKHEKQLFSTEVVVALIHTLGVYPPGTVVSLSDGSFGLVLNINFKNRMKPLVLMYH
                     PTPGQEPHTIDLLRDQTLSILRAVPREELPRPIVEFFRLKRWTGYFIQATMRTA"
     gene            33081..35273
                     /locus_tag="PK063_07275"
     CDS             33081..35273
                     /locus_tag="PK063_07275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HMZ96885.1"
                     /translation="MALPRVLLIIPPLTQLNTPYPATAYLTGFLRSRGYEAEQADLGL
                     EMILRLFSRVGLQEAFHRIKASRRPWRGEVQQFLALEDSYLATIDPVIAFLQGKDPML
                     APHLARPGFLPEGPRFGADGRPGSSPFPTSPTDSARHRATLYLEDLTDLLYETIAPHL
                     FLNRYAEQIMQATSSFDGIEKALAEPLSFTDELLLEALAPLLAGSSPDVVGLTVPFPG
                     NLFGALRIAQAIKAQRPATAVVLGGGYVNTELRRLKDPRLFRYVDYVTLDDGERPFLC
                     LLDFLAGGRSQPHLCRTFVLADGQVVFRNGNTEPDLSMHELGTPTYNGLPLGRYLSIL
                     DSLNPMHRLWSEGHWNKLTVAHGCYWKQCTFCDVGLNYIARYEMTPTDVLIRQIEALI
                     RETGQRGFHFVDEAAPPAALKALALRLLETNQTISWWGNIRFEEAFSPDLARLLAASG
                     CIALTAGLEAASDRLLRQMKKGITVDQTARVAAAFRHAGILVHAYLMYGLPGESIADT
                     VDSLERVRQLFANNLLQSAFWHRFTATAHSPVGLNPAAEGITILGPTFEGFAENDLRH
                     ADPNASCPPWLGEGLRTAILNYIEQAGLTVPVQQWFPQAVQAPRVAKTWLTRALADAV
                     PEPLTAERRCVWIGGRPVVAAKGTTRVKIILPTRMEDFSISVSSDQVDWLMDLLQNAS
                     PSLHRTDRDYPRFAEARERFPHTGARGFDRFARTAAWHNARQAGLLLV"
     gene            35533..36363
                     /locus_tag="PK063_07280"
     CDS             35533..36363
                     /locus_tag="PK063_07280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96886.1"
                     /translation="MMTPRLLTLLMATGIVCAAPLSASAIAVYSSSGSNAASIQGSVD
                     GFRADLGTNNLANAPATGGRREINWDGVPAGFSDPNHLPGNFFNSNSPRGAVFETPGS
                     GFKVSANTGVGTPERFGSINPSFPSSFSVFSSQKLFTAIDSNIVDVKFFVPGTTQAAN
                     VRGFGSVFTDVDLLGPTTVEFFDMNNNLLSKQTVLNTPGATSLSFLGVSLEQAIINRV
                     RITAGNAALSNLDGFDFVAMDDFIYGEPQAVPAPAAVLLLASGLAALVWARRNSLLPE
                     "
     gene            complement(36542..37177)
                     /locus_tag="PK063_07285"
     CDS             complement(36542..37177)
                     /locus_tag="PK063_07285"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HMZ96887.1"
                     /translation="MGLRLGDDAPNFTAETTDGTINFHEWLGNGWGILFSHPKDYTPV
                     CTTELGYMARIKGEFDKRGVKILAISVDPLDSHRGWMKDINETQNCTVTYPIIADPEK
                     KVANLYDMIHPNSLDSMTVRSVFVIGPDKKIKLMLTYPASCGRNFDELLRVVDSLQLT
                     AKYKVATPVNWKDGQDCIITPAVNDAEAKTLFPKGFKSVKPYLRLTPQPNK"
     gene            37383..37742
                     /locus_tag="PK063_07290"
     CDS             37383..37742
                     /locus_tag="PK063_07290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HMZ96888.1"
                     /translation="MRQPATGLRIANDPMYRLLREGCIKEFNVKRAAGEPVDLTRCDL
                     RGLDLRGLEVDGLDFSECYFRQADLRGIDFRKAKLEGASINAAKISGAYFPIELTASE
                     IELSLLHGTRMRYQPKP"
     gene            complement(37757..40696)
                     /locus_tag="PK063_07295"
     CDS             complement(37757..40696)
                     /locus_tag="PK063_07295"
                     /inference="COORDINATES: protein motif:HMM:NF017197.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF748 domain-containing protein"
                     /protein_id="HMZ96889.1"
                     /translation="MTFLSRYRLLLYVLSGLVALYALLGFVVAPYAVKTYGIPALSER
                     LVHPVVLGDMRLNPFTFSIELTGFEIQEPDHTPMIGFQELFVDFEATSLVRSSYLFDE
                     IRLTLPFGLVHLQADGKLNLLGLVPPGSQEAERPAPPVEQPRKEPMPSIEIRQLSIQR
                     GVIEYRDDSKKRPVTIDVVPIEISVRNFTSRGRGENAYAFTAEFGEGEVLAWEGTLHL
                     DPLESDGHVSLSHVGLKTFWPSLRDRFRFDILSGTLLVDVRYHFDTHLAPINLQVTEG
                     KVQLADFRLSEAGSRDPVVTVPSFGIEGINMDLSKRELGIGTVALTGAEVRAWLGQDK
                     VVNFQPLFAPVAATADASPPSEPPAPDAGQAWKVAVQSVEVANTQVAFEDRSLATPVE
                     LLLDDVHLTAGDVHVPFKGAVPVTAGFRLNQQGALEAKGTLRLDSLQAALALKLDHIG
                     LRPFQPYLDRFVQLEVRDGELMLDGDLVYRSRHESEPMLQYRGQAGLNNLHVADRAST
                     KEFLGWTALSLSKMALDVAPTTVKIGEIALRDPAFRLITDKDGSTNLSRVLRPSDTPP
                     APASKPVEPEAPKKPATPTPVEIAVVRLTNLSATFSDESIVPAVSTGITDLTGTIKGL
                     SSRQIAKAEVALTGKVDEVAPLKIQGQINPLSEDTFTHLTFVFQGVDLTSVSPYAGKF
                     AGYPITKGKLSLDLMYQISKKQLVGENKVLVDQLTFGDKTDSPDATTLPVRLAVGLLK
                     DRRGRIDIDMPVRGDLNEPDFRYGRVVLNALVNLLTKVVTSPFSALGGLVGGGGEDLQ
                     FVEFQAGSDSLAEPEQRKLESIAKALEERPALRVDVTGVADPVRDRQALALQKIADEV
                     LRRFTKGGTKNLQAVPSPSREFELLSDLYAEKLGKQPMKREELPGGKSVERVLTADEL
                     RQQLFPAMTVEDAELRGLAQERAKAIREHLIAQGHLPDERVFLVEAELAASDKPQIRV
                     HLSLTGS"
     gene            41000..41407
                     /locus_tag="PK063_07300"
     CDS             41000..41407
                     /locus_tag="PK063_07300"
                     /inference="COORDINATES: protein motif:HMM:NF015735.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciI family protein"
                     /protein_id="HMZ96890.1"
                     /translation="MRFLVLMIPGVYQPNTNRQPKANFTPTAEMMAKMGRFNEELKQA
                     GALLSLDGLQPLATGARLAFSNGKASVTDGPAVDAKEVVGGFWMLQATSKQQVIDWMT
                     RCPALDGDVIEIRQVFELSDFQEDVQATAKKHG"
     gene            41500..41994
                     /locus_tag="PK063_07305"
     CDS             41500..41994
                     /locus_tag="PK063_07305"
                     /inference="COORDINATES: protein motif:HMM:NF018663.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HMZ96891.1"
                     /translation="MTKPAKNTICLWYDRDAEEAARFYAKTFPDSFVGAVHRAPGDYP
                     SGKKGDVLTVEFTVMGIPCLGLNGGPAFKHNEAFSFQVATTDQAETDRYWQAIVNNGG
                     EESECGWCKDKWGLSWQITPVVLTDAVTNSDPAVAKRAFDAMMQMGKIDVATIEAAVR
                     GSKT"
     gene            42757..43860
                     /gene="fbp"
                     /locus_tag="PK063_07310"
     CDS             42757..43860
                     /gene="fbp"
                     /locus_tag="PK063_07310"
                     /EC_number="3.1.3.11"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: protein motif:HMM:NF014057.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphate aldolase/phosphatase"
                     /protein_id="HMZ96892.1"
                     /translation="MKITLSIIKADIGSIGGHICPSQQLLQTVRSYIAQHGSPLLIDH
                     YLSSTGDDIAILMSHTHGPGHEAIHKLAWDAFVAGTEVAKKQGLYGAGQDLLKDAFSG
                     NVHGMGPAVAEMEFDERPNEPFLFFAADKTDPGAFNLPLYLAFADPMNTPGLMLAPNM
                     ARGFRFVIMDVNHTDGDRIIELSAPKDLYEIAALLRDTERYVVESIWSLSSGEQAVAA
                     STSRLHNIAGKYTGKDDPVMLVRVQKDFPATGEVLAPYAIGPYVAGGMRGSHQMPLMP
                     VPLQSGISYFDGPPVITCAAFAMHAGRLTEPVDTFVHPFWDRVRDNVSEKAISMRRQG
                     FFGAAMLPMAELEYTGIMEKLKGLDASFKVRKA"
     gene            complement(44016..>44541)
                     /locus_tag="PK063_07315"
     CDS             complement(44016..>44541)
                     /locus_tag="PK063_07315"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ96893.1"
                     /translation="RLLLPLTSSATGLQPVKGGATVIQAHSDSAPPSLNVTAPIRTLL
                     VDDHPMMRQGLRSLLTTFANIDVVGEASDGQEAVELAERLRPRLIIMDVNMPRMNGIE
                     ATAVIKSRLTDTSVIGLSVHASPETDRAMRAAGAAILLPKETAAKALYQAIQKVLTDG
                     LNIPDGAMGDCIKA"
BASE COUNT         9180 a        13551 c        12383 g         9027 t
ORIGIN      
        1 acggctgccc ttctcctact tccatgtgtt cagttattca tcccgtcccg gcacgccggc
       61 ggcccgcctg gaacctcaga cgccgggcac catcatccgg caacggagta aaaccctcgc
      121 agagttgtct cgcaccaagg cgctggcgtt ttatcagcgg cagatcggcc gtaccgtctc
      181 cgtgttgttc gaacaggggg agcacgacgg ctttcgaacc ggcaccacgg cgaacttcac
      241 tcgagtggcc gtcccggccg atgcggtcgc ggccggctct atccaccctg tcaccattac
      301 cggcatcatg gatggcttgg cctatggtca tctggcctct ccgtccgtgg agccgacata
      361 tagaccattg ttatgacaca acccaacaag ccccataccg tccatatcga aaccttcggc
      421 tgccagatga acgagtacga ctctgaactc gttcggacgc tgcttcgtaa agcgggattt
      481 gaattcaccg aggatcgcga gcgcgccgat gtgatgctca tgaacacctg cgccattcgt
      541 gaaaacgccc acaataaggt ctatgggcat cttgcggaac tcaaggccgt gaaggaacaa
      601 cgcccgctgg tcgtgggcgt gctgggctgt atggcgcaaa acctcaaaga agaactcacg
      661 gaaaaacagc cgctcgtaga cgtgttggtg gggccggatg gataccggca gttgccgggc
      721 cttctgacga atgccctcaa tgccgaagag cagggactct cgcgccgtgg gctggccgtc
      781 gatctgtctg aatacgaaac ctacgatgac atccttcccg agcgcgacgg cggctgcaat
      841 gcctggatcg ccatcatgcg gggctgcgac aatttctgca gtttctgcgt cgtgccctac
      901 acgcgcggac gcgagcgttc gcgcgatccg cagggtatcc tgcgcgaagt ggaggtctcg
      961 gtggaggccg gccacaccca gattacgctg ctcggccaga acgtgaactc ctaccggtat
     1021 gacgattggg acttcgcccg cctgattctc gcggtggccg aagtaccggg tgtccagcga
     1081 gtccggttta cctcccccca tcccaaagat tttcctgccg cgctcttgga tgctgtggcc
     1141 ggtcatccga acatctgcaa gcacattcat ctgccgttac agtccggcaa cgaccgtatt
     1201 ctcgaactga tgaaccggac ctacagccgg aaggaatatc tcgacctggc caccacaatc
     1261 cgccgtcggc accccggtat cgccctgacg acggatatta tctgcggctt ctgctcggaa
     1321 accgaagagg agttcctgga tacgtttcga gtcgtggagg acgtgcaata tcactcnnnn
     1381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnattc tcgatggaag cgccgccgtc
     1501 ctcatgggcc ggggcgagcc tggtgccact ctctcgtgat tcatccctca gttgttcaca
     1561 atcgaatgac ccatcaccgg tcattgcacc ggacgatcgg ctcccctcgc aatgtggacc
     1621 aatcgtcctg tgcagaaaga ggaggatctt attgcccagt tctgaacaat tcttgccaaa
     1681 ttttagacgc ccgcgcgcgt cagactgaca aaaataagga acgcagatac gacgtagcga
     1741 gttcgtattt tccaaccttc tcccgagccc atcacttctt gcctctcaac ggagcctttt
     1801 cactgccttg aaacatcaat agcttaggcc ccagtgttga gcgtgtgccg ccacgtctca
     1861 gctcaacatc cattacagac agcaattgaa cgggagtgag aaatcgcact tctgaagtct
     1921 ttgtaaacag ggcatagcct ttgcttggtc cagtctggca accacaccaa ccacccgacc
     1981 gagccagagg acgccgtatc atgaagaaag acatcatcca gacccacgta gaagaagccc
     2041 ctaaggggat cagcctggaa accatcatcg cggttggcgt cttcgggtgg atggctctcg
     2101 gcgtggtgat gatgggtctg gggatctggt aatcccgatc cgtcgtttcg cctgttctct
     2161 ctgaaaccgc accgcctctg ttcgtcaccg cttcgaccag ccgagaagga agaccgccat
     2221 gctgattcac ggctcccact cctttttgat gcaccgcctg aactccggaa tcctcggatt
     2281 gaccttgatg ggagccctgg cctccggttg ttcctccacc gccgcctcgg ttcagcaacc
     2341 agccgccatg cagcctcaag gctccgtccg gctggaagaa gtcgccgatt gggaatttga
     2401 agcctcccat cccagctcca tagatgccgc cacactcgac agcctgttgc gggccgtcgt
     2461 gattgcggag gcgcagactg atatgtcgaa tctgcccgtg gatggcagca agccgatgac
     2521 agtgttcagc gatgaggatg tgcgttatct tgctcccctg ctagcccaag cgttgtccca
     2581 agcgcaaccc gaatacgtgg tcgctttccg gctctcctca tcggcagggt caggctctga
     2641 acccaccgcg ggcacccttt acgtgaagaa cgaccggttg tatctcaccc tttccgagca
     2701 ccacggttcg ctggccaaaa ccgagtcaac atggctgggg agcgggcgag cggctcgaat
     2761 cgtgagcgtc atgccggcct ccgccgggca gctcgaacaa gcgttgccgg ccgtgataca
     2821 aggacggcag cagatgaagt cgcttgcgat cgactatcac cagtttgcca aaaagcccga
     2881 accggctccc atgaccgcgg cgaccactgc tccggctccc caacctgtcc aagccctcag
     2941 cgtgcgaaac gtccctgccg tggcacccga tcaaccggcc aagcagcaat ccgcgccggc
     3001 gccagtcatg gacaaggtgg cgtcgaacca ggcccctgcc gaagatgaac gtttgaacga
     3061 gacgcttcaa gaattgcagg acacgaagga cgccatggcc cgtaaggacg ccaagatcag
     3121 cgcgctgcga agagatttag agtcgatgcg gatgcagttg gaaacgaagg ataaggaact
     3181 ccgggcagtg aaaaacactc agcagcagca acccaaacgc gagacccgca ataaggcaga
     3241 actgacggtc cgctgacctc gcggaccgca ttcagcccac atcgaccagc tccggcttca
     3301 gcagcacaat ctccctcgat atcggcggcc ggaaattcat ccggcagtag catccatagg
     3361 tcacataggt atcctgcagg caatagaggg caatctcttt tccctgcccg tccgcccaca
     3421 tttgcgcgac ctgggaacca ctccccgatt tgctttctac attcaacgcc cgggcaagca
     3481 catccagctt gacccatccc cggttatccc agttgctcca aatggccatg gtgtcgtaga
     3541 ccggctccgc gcggaacttg gccaggttga tctccatact gggcttcact tgttgaatga
     3601 tcgaccgttt tttgatgaag ggcagatcga aattgagtcc gttgtgggtg atgaacaacg
     3661 acggacgcga ctggcccaga tggctccaga aggcccgcag gagtgcctgc tcattccccc
     3721 cataccacga gatggcaccc ctcggttcca gggtatccgt gaactccaac agaccgatgc
     3781 agacgatctt gctgaacgtg ccgtcgaagg aagacttctc atacagttca tcatcgagcc
     3841 gctgctgagc ctccgcctcc cccacggcaa atagatcacc gccgctctca gcgaaagtga
     3901 cctcgcccga cgtgagctgc cgccctgcga tccgcgccca ttcttctctg ggagcctgca
     3961 cggtttcgat atccagcacc actttcatac gcccctacac cttcctctgc tgaagcgccg
     4021 caatgacggg ctggtcggcc ggcggaaact cgaaggaggc catctcatga ggatagaccc
     4081 atcgaagctc cgcgcaatcg atcgcgatcg caacacccgc ctcgatgcgg caacgaaaga
     4141 aatgcaatac cacaaccttc tcgggatatt catgccgtac gatctgaaag ggagtcagtg
     4201 cgctgactcg aacctgcaac tcctcccata actcccgatg cagacattcc tccagcgttt
     4261 cgcctgtttc acgtttgccc ccgggaaact cccacaaccc tcccaggtgc gcgccggctt
     4321 tgcggcgggc gatcaggtag cgtccttcgt gagcaatgat tccggccgct acttcaatca
     4381 cctgcatcgc gaccttcccc gtatcgagtc gttgcaccat catcccttcg cactctgcga
     4441 tcagtcatgg gatgacccgt tcgtcgagga ttatttctca ccgaacggat aggttttgca
     4501 cagcggtttc atgggacaga ggaggcaata gggattacgc gccgtacaaa tggtggcgcc
     4561 gaaatccatg atcgcctggt tgaaatcgta ccccttacct cgaggaatca acgcttcgga
     4621 gagttcccag agcaacgctt tctgtccctt cggatccccc tcggcgatga acacccggtg
     4681 caagacacgg atcacgttcg tgtcgaggat cggcgcgtcc tcgttgaacg cgaaggagcg
     4741 aatcgcgccg gccgtatacc gcccgatgcc tttgaaggac aacaattcat ccgcatcact
     4801 cggtagttgc ccgccatagc gggccacggt ttcacgcgcg atactgtgta accgctcggg
     4861 acggatgttg taccccaacg ggtaccaggt ctgtttgacc tccgctaccg gggcatcggc
     4921 caattcggca aaggacggat accgctccaa aaattcatgg tacttcggga tgacccgatc
     4981 cacttgcgtc tgctggagca ttacctccga gaccagaata tgatagggat cggacgtctt
     5041 ccgccagggc agatcgcggc catactcttt gtaccacttg agcaaccggt tctgaaaccg
     5101 ctgcttctgt ccgcgcgcaa gcgggagggc gggagttgac gtctgcttct tccgtcggga
     5161 aggtttctga gtgcgaggct ttgtaggcat aacggtccgt ggaggcgtgg cggcattcta
     5221 aaaggcggtg gggtgaaaat caaaccagcg tgaaggaacg ggagaggacc gcaggacagg
     5281 gtctcccaat ggaatactcc ccgtcctgcg gcgtgtgatg cgacgttaca caagcgatgg
     5341 tgttactgcg gtgaggcctg caccttcgtt ccctctttta cgggcggatc gatcacaata
     5401 ttgggtccct gcaccttcgg caaaatcccg gctccgggct tctcgagcag gcgctggttt
     5461 tggtcgttga tcgaaagttt ctgtgacacg tgccggtcat caaatgcggc ggagccagca
     5521 agtgcggatt ccccgccgcc gttggcacgt ccaggatcgt tagcgagagc ctggccgttg
     5581 accggatcgg tcgctttgcc catcggatac ccgggatgct ggggcaacag cgcaggattg
     5641 gcaaaggcta cggcagctcc caacattcca atagccgcca acgcatatat ggagaacgag
     5701 gctttcatac gacacctcct ttggggcgga taacatgaca gcgccctgcg gccgaccagc
     5761 cgcagggcgc acaatgaacc tccggagttg aaaggagtcc tctcttgctc ttgcggaaca
     5821 attcaccccg gcatggcaag tatctcccga tacctttcca gcttcttcct ccataagaac
     5881 ctagtcaaga gggcgatcat catccgacta agccactctt ccgggcatga ttgatcagca
     5941 cgtagtttga agaaccacaa acggatgccg attttcaggt cccattcctc aaatcaagga
     6001 ccagagccga tttcctgccc taggactttc cccaccgcca aatgacccga gacattatcc
     6061 tgatcgcaca ggcaatggag ggcatggtat gtcagtctgc cggcccactc gtcgcccgag
     6121 gccttcgctc tttcgcatcg gcgatgaagc gcgagacgtt gatgcgacga gcggctctgt
     6181 ggactcgttt caggcttcac ctggagttcg acggtgcacc agggtagcgc cattattcac
     6241 tacacccgag gatgcacagc aatacatgtc catgaccgtt cattaccgtg tgtccctgtc
     6301 cgcggattcc acgacgactg gagaaggacg cctgttagat ctctccctgg aaggctgccg
     6361 gatcgaatgc gaccggcatt tgccggtcaa tacctacctc tcgttacgtc tgcaaatctc
     6421 accgaatgag atgccgattc tggtggacct tgccgcggtg cgatggactc gcggtaccaa
     6481 ttgcggggtg catttcttgt ccgtccagcc gctgcaatcc gcacggctgc agacctttct
     6541 cgccgccgcg tcgccccgga aagaaccacc gactcccggg gcaggttaat ccgatctgct
     6601 ccagccacta gcccgaattt gcccttgcct tttnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6721 nnnnnnnnnn nnnagaggcg aatcgtactc tcctcgtacg gtgagcctct gatcgaagcg
     6781 agaacgccgc tggaagcctt ttccaacagc ctactaccag tcggcaccta ggcgatccac
     6841 aacgagttgg tgcaccaccg cctgagggcc caaagaggcg agatacagag cggcctctgc
     6901 gatgtcgaac gggtcgattt tttcgctggc cgctctcgct tctggcgtgg catcaaccag
     6961 ttcgtcggcc accccgccgg gacagagcgc gctcacctta atccgatagg ctcgcccttc
     7021 gtccgccaac gacttcgtca gcgccatgat ggcatgtttg gaggcgctgt aggtgcccgt
     7081 cccgctccag gcctgcacac ccgccacgct cgacatattg atgattgtcc cgccgccctg
     7141 ttttttcata agcccgaagg cggcgcggca gcagaagaac gttccccgga cattggttcg
     7201 catcacttca tcgaacgcct cggtgctcgt ctctgccaga cggcggccgc cgaagatgcc
     7261 ggcattgttg accaggatat ccagacgctg gtatcggcgg atcgtttccg ccatgagctg
     7321 ctccacctgc gattcatcgg caatatccgt ctgtagtgcc actgcccggc ccccggctga
     7381 ttcgatctgc gcgacggtct cttcgcactt gtagaagcgc cgtgccgcaa cgaccactgt
     7441 cgccccttcc tgcgcaaacc gcaaggcaat cgctttgccg attccgctgc tgctgcctgt
     7501 caccaccgca acttttccgt ccaagcgctt catatcgggc ctccccttac cttcgatgct
     7561 caggacaatg tgtgacgtcc tattcgtcca taggatacag gtgaaacccg gcatggagaa
     7621 agaaggtgga agcaacgcta ccggaagcgg ttggcagaac cactactgag gatttttttc
     7681 ggttggattt tttacggggg aggtgtgact gtccacattg tgtccgagca tgtggcctac
     7741 ccgtccaagc acgatttgct ccgcctcttc acgtgtcgcg catggaccgg aatcaacgga
     7801 ctcttcgcgt ctcttctctc cgactccgca acggaaggta gcctcgacgt accattgttc
     7861 accgccaccc tggtgaaagg tgaggtggac gtcacacccc acaatgcgaa tatccttcgt
     7921 gtcgttggag gagcgaaatc gattgagcgg gctcatggca tccatccttc cggttccgcc
     7981 tattgagcgt accgcggaag actcggccca cgtactaggt gaaacccgcc ccctcatcac
     8041 atccggttct agccagacac tggtatcaga ggtgatgaga aacgaaggcc tgttcgccga
     8101 tcgccgcccg cgcgacgtcc aggagatggc gatggtgagt gaagatcagc acctggccct
     8161 cttcggcgaa gagagccaag gcccggagga tgtgagcgac gcgccggtcg tcagaggtaa
     8221 tcagcgcgtc gtccagcacg agcggcattt gcggatgggc ctcccgacgg atgtccagcg
     8281 ccgccaatcg caaggcgaga tacaattgat ccgccgtgcc ctcgctcatt tcttcaaccg
     8341 cgaccgacgt gccgccttgg cgcaatgcgc ataaccgcgg ctgccctccg gtgtcgtcac
     8401 tgatcaatcg ttcataatct ccgtcggtca tgagcgcgaa ataagctgag gctttcgtaa
     8461 tcatgggcgc ctgtgcccgc tcccggaagc gattcaaggc ttcctgcagc agtgcgcggg
     8521 ccagtttcag tctggcccat ggcctgatgg ctgagcgata ccgtgcggca gccgactcca
     8581 tcgcttcacg ggcacgggct gcgcggtctg aggagtcgat ggcgttcaga gctaatcgcg
     8641 cctgctcttc cgcgcgacgg gcagccgcct gctcttcttc acatctcgta atttccgatc
     8701 ggcactgttc ccgctcggtc tcgatcgtca ccgcatcccg gccggacagg cgctggcgta
     8761 gctcctcgac ggaaagggac gatgcggcag cgatctgttg ccgcacatgt gtatggctgg
     8821 cggatgcctc ccgtttgcgt gaggccgcct cctcacgttg cggcaagtcc tcgagaccgg
     8881 tcacccccgc cactgcgcac agccgtgcca atatggtctg ctgcgcggcc cggtccgagg
     8941 cagcgcctcg ccgcttctcc tcggctttcc gctgatcccg cagcagcgtc gcctgctcct
     9001 gttccgcagc ctttgccgcc gcgagcctgc cgcgtaaccg atccgcaaag tcctccacca
     9061 tctgaggcgc cggtatatcg agtactgccg ccacatcctt ggactgtgcg gccaggtcat
     9121 cgagaatagc ctgtacctgg gctctgcgct gctttgcctc acctaaggct gccgcctgcc
     9181 gtgccgcgcc atccagttcg tcgagacgca ctttaatcgc atccggaatc gtatcggagg
     9241 cgaggaacaa ccgcgcatgc cacgcctgca atgcggactg gtggcgccgt aactccgccc
     9301 ccatctcagc catcgaacgg tcgagttgct ggcgttcgat ccgttgcact gtggccgctt
     9361 gttctttcgc gttgtgagcg gcttcagcct cgacggcctt gctgtcatag gccaccgcct
     9421 gctcgatcaa cgacggcaac agcgtcacat ccacggggtt cgcctcactc actggatggc
     9481 ccagctttag caaggctgcc ctgactccag ccaccgcatt gttcgtctct tcctgcaacc
     9541 ggtcacttgc agcgcgcagc cctgccacgc gttctgcaat ctggagcgcg tcggctcgcc
     9601 gcccctgcca ttcccgtaat ggttcgggat ccaaatcagg cagaccggcg tctttcagcc
     9661 gttgtgccca tgcgtcaagg gtcgccccgc ggcctgccga aagtcgtgct atctgtcgtt
     9721 cgatatccga tcgccggccc tccatctgct cgatgcgtcc cgtgcattcc tccaggccgg
     9781 cggcgcgttt ggcatccgcg cgcaacagat ccgcctgccg gtcggcctcg ctcagagccg
     9841 cttcgaacat ctccggtgtg gcccgtgcag tatcaaaccc caaggccagt tgatcgaggg
     9901 tctgagtacg gtcgatgtac gcctcacgga tggccttcca cctgtcgtct cgcttggccc
     9961 gcgcctgacg taacgtctcc gccgtgacga tttcgccctc ggcggccaac tgcctgagcc
    10021 gcaggcgttg cccatccaga tcgcggccca ctaattcctg ttcatcgcgc aacttgcgga
    10081 tctgctcgtc gagatcgttc aattcctgcc tcgtacgcgc aatctgtgcg tcgagcaatg
    10141 gttgagcgcg gcgcaacgcc tggtcggagg ccagtccgac atcggccaga gcctgttcga
    10201 gcagaaggtc catttcacgc cgctgctgat ccagttcctt ctgccgccgg accacatcac
    10261 caagcgattg ggcatggcga acggctgtca tgagttgctg tctggagccg ggatcgatcg
    10321 ggagccagga ttcctggtga gacgaagcca gggcctggtc caatgccgtg gcgcgttgcc
    10381 ggatatgttc gagccggtcc tccaatcgac tcacctgcat caggtgatcg tccaggacca
    10441 ggcggtcggc ggcagacggc acggcgtgca gcacatcacg cacctcacgt ccgggcgcga
    10501 gtcgcgcgat ggctaatccg aggtccgcat cgagtgcggc aatgactgca tcctgttgtt
    10561 gcacctcgat ccgatagcga gccgccgccg cgaccccaga cacgaatcgt tcgatcgcag
    10621 cggcatgctc caggaccaat ggctcgaggg tcaacgcgcc aagcgcacgg gcgcatcgct
    10681 ccgcctcgac ctcagcttct ctcaggctgt gctcagcgtg gttgagttcc tgtaacgcag
    10741 ccaaccgcgc ttcccgcgcc tgttcgggca agtccggaac tccggcgaac gacgccaaca
    10801 aggccgtcgc tgcgtcatgg gtgcgcaaca acggtccgac tgtgcgcaat tcgatcaatt
    10861 cgttctcacg ccggcgcagc cgttcgagag tcatactcac gtcagagagc gtcgctgctg
    10921 ccgcctcgtg cgcgcgatac aagctttgcc actccgccgg cttggtttgg gcttcgcgcc
    10981 aggcctgccg ttgttcatcg agccgccggc gtgcctcatt gatcaccgcg ttctgcgccc
    11041 gtccatgcgg gctatatagc ttcttcgcgt cggtctccaa cgctgcgagc agcgtcgcga
    11101 tgccgctggt ccctgcgctt gcttcgaaca acgctgatcc caaatccccc tcgccgcgca
    11161 gaagcacctg tccgccttcg cgcaaacgcg catgggtgag accgaacatg gcctcgaact
    11221 ccacccgctc cagcccgccg gtcaaccccc gttcgtggcc cggttccatg acgagcgatt
    11281 gatctggttg ctccgtcaga acattgagcc gcgccagtgt cgtccccttg cccttgcgcc
    11341 gcacaaaacc gatcgcctcg ccattgatcg cggcgaaaat tcctccgatc cgaaggtcac
    11401 cggcggcatg gaggaaatcg tccgcgcttc gcacagggat gccgaatcgc aaatccatca
    11461 tggctcgcaa ggccgacgac ttgcccgctt cattgggacc ataaatcacg tggaggttgg
    11521 cagggcccgt ggaaaaatcc agcaccttgc cggtgaatgg accgtaggcc tggagcagca
    11581 gcttgagcag tttcatgcct ctgctccaag atcagtcagc cgtgccaata ctgtggcttc
    11641 cgcctccatc aggagctgtg tcaattcgac gcggtcgtcg agcttcggca cgtctccagc
    11701 cgccacttcc tgcggaagcg agcccagcag atcgccgagt tcgacctgcg cccagcgctg
    11761 caactccgat tcgtcacccg ccacggaatc gacgagacgg acgagttcac ccaccgcatc
    11821 ctggcgttgc gccgtttgaa cgcgatcaag cggagtagtg aggtcaagcc ggacctgctc
    11881 aatccagact tcggcttcgc caatgtcctg tgccgcccca tacatcgccg cagccaacgt
    11941 gccgggctgg ctcgcttcca ggcgatggag ttccgtggat cccgtcaggg ttacccgtac
    12001 cgcgtgcagg cgatccattg cgccgatgag caccggctcc agggcatgac ggaaggcctc
    12061 tcccaaagcc tccagcctct gtacgccatc gagcgaaacg atcagctgat tccagcgcac
    12121 cacatccagc gccacgaatt cgctttcgat tcggcccgcc tccaccgtca ccaactcgca
    12181 ccccttcggc cccgtttcct tcgcatggcg gccctgcagg ttgccgggaa atacgatgtg
    12241 cggccgctcg gcgatcactt ctcgcgcatg cacatgcccc agggcccaat agtcgtatcc
    12301 tttgtggttc aacgtcggca ggtccgtcgg cgcgtaggtg tcatgcccgg cgcggcctgt
    12361 caggctggtg tgcaagagac cgatattgaa gaagcccggc acaggcggag gataagaagg
    12421 gacaaggtct tcatcgaccg cccgttcggg aaagctgcgg ccatggatcg ccaccgagcg
    12481 atcgtcgagc ctgatggtgt gagccgcgcg actggaaaat acggtgacat tcggcgggag
    12541 gacgagctgt ttggagatga caccctgcgc atcatggttc ccttgaacga tgaagacccg
    12601 gatcccctct cgctccaacc gaaccatctg cccgcgaaaa aacaggccgg tatgaaaatc
    12661 ctgccagtcg cagtcgtaga tatccccggc caagagcaaa aagtccacgt gttcactgat
    12721 cgctgtatcg atcagccgct cgaaggcact gcgtgtcgcc gtccgcaacc gctcaaccgg
    12781 agcgccgtcg tagcggtcca gcccgcgcag gggactgtca atatgaaggt cggccgcatg
    12841 aataaagcgc atgacgtaca ggtccagagg agttcacgat cacccacgca tcctacgatc
    12901 ataaatccgg atggacagga caagcgcggt gcgatcccgc atgatacgcg agtggccagg
    12961 tcctcacaat gccggcgcgt gactcctctg tcatctgagt cccgcccgcc ggactcggcg
    13021 ggcgggacaa agccagccta tcgtctggct gcttgtttgc ggcacccaca ttgacagttg
    13081 atctgcacgc aacggcaggc attgggctga cacccgcatg cacaggatga acagtcgcat
    13141 gttccgcagc acccgctctt ggcgattttc tgggaggtgg atgtcttcgc atcggccatg
    13201 gtggtctcct ttggtaggtc aacgcgtgat tgcgtcgtca cacaggctga cggagagcgt
    13261 tcgaaaacct tacagttcaa cagagagttt ggtaagctgc cgtcatgtca ctcgaatcca
    13321 caccatcgac agccctttcg ccggaggcca ttgcgcagct ggtgcaagga cataagcagt
    13381 tcctggcgtt cctcgagcgg cgagtcgaat ccagagccgt ggcggaagac attctccaaa
    13441 gcgcgtttgc acgtgggtta gaacgcggcg ccggcgtgga cgaagaaaag gtcgtcgcct
    13501 ggttctatcg tgtgctccgc aacgccgtga tcgatcacta ccgccaacga tctagcgctg
    13561 agcgcgcggt ggaagcctgg accagagaat ttcccgatgt ccaggaaccg gcggcggaac
    13621 tgcgacagga gatctgccag tgcgtatcgg ggttgctcga gacgctcaaa ccggaatatc
    13681 gcgaagccct gcaaatcgtg gatctgcaag aaggtaaatt gaaagacctg gctcaacaat
    13741 cagggatcac agctgagaat gcggccgtcc gcgtgcaccg ggccagagcg gccctgcgtc
    13801 gccagatcga aaaggcctgt ggcacctgtt ccgtgcatgg ctgcctcgac tgttcctgcg
    13861 aggcatccgg cggatcgact tgcggggcat gaggacaatg cagcannnnn nnnnnnnnnn
    13921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13981 nnnnnnnnnn nnnnnnnnnn nnnnntgttc ctgcgaggca tccggcggat cgacttgcgg
    14041 ggcatgagga caatgcagca gccgacatcc gaacgctatt cttgcatttg cggcaactgc
    14101 ccccgtatgc tcgaatcacg atgactgaac caaccatgcg cctctcgaac ttaagccttg
    14161 ccgaactgaa gagcctggtc gaaggcctcg tcgatgaccg gctgcgagcc ttgctcggcg
    14221 atcccgatct gggcgcgcca ctgggtgagt ccgtccgcga acgtttgaag cagtcgctct
    14281 cctcgacaga gcgtctttcc ggtgacgagg tagccgacaa gctcggtttg cggtggtaac
    14341 atgccctggt ttcgcctcgc gttccgcccc gatgtgatca ccgacctgcg cgctgccgac
    14401 tcctcaatgg ctcagcggtt gttcgacaaa acgaagtggc tggcctccaa cgtggagaat
    14461 ttgcggcacg agcccgtggc ggcggatttg cccggcatcc ataaatatgc cgtcggcgac
    14521 tggcgcatct tttactcgat cgaccgatcg gaacagatgg tggacattca ctacatccaa
    14581 caccggccgc aagcgggccg cactcccgga gcctgacgat gctcaccctt acgcagaaag
    14641 ccgtcgaccg gctgcgggcg ttgttgctgg agcatcctga agacccggtg gtgcggattg
    14701 ccgtgcgcga tgtgaatgag cagcggctct cccttgccat tacactggaa gcggcggttc
    14761 gcgaagagga tgtggtcgaa cagattgaag gcctgacgat cgcattcgat cggtcgagcg
    14821 cacatcggac aggcgggatg acggtggatt accaggccgg acgtttcagc tttgcccatc
    14881 cccctgcgaa tgagctgggc ctcatcatgc ccggccgcaa ctgaagtgag tgaaccgtta
    14941 caggtacaac gtcagtgtgt ttgacgtgtt ccgtttcatg ccttggcgcc gctcacgatt
    15001 tcatccgcgg aaatacgctg ccgaaatgca tagtgaaggt acctcgcgcc acatccgcaa
    15061 catagcgttc cagggcgtcc tggatcacgg gaaaggccag gtcgtcccac ggaatggcat
    15121 ccagcgtgaa caattgcaca tccaggcttt ccgtaccggg tttgaattcc ggcgtgcgca
    15181 tggtcccgcg aaaaatcata tgcacctgac tgatgcgggg caggctcagc acggcataca
    15241 gggaggtgat ttccacttcc gcatgcgctt cctcgaacgt ttcccgaacg gcggcctgtt
    15301 ccgtgctttc gccgatttcc atgaagccgg caggaaacgt ccagtggccg atgcgaggtt
    15361 cgatcgcccg gcggcacaac agaattttgt cttcccactc gggaatacaa ccggcgacga
    15421 ttttcggatt gatgtaatgg acgacctgac aggtttcgca gacaaaccgc ggcaggttgt
    15481 cgccgggagg aatttttttc gacagcccgg ccccacactc gctgcagaat ttcattgcgg
    15541 ctcccgatca cgacgagaga aagacagaaa tggatagcac aattcaggca ttctttgcac
    15601 cctgcccgcg cggcctcgaa gccgtcctgg cggaagaact gaccatgctg ggcgccaccg
    15661 ccgtcaaggc caccgccggc ggagtagcct ttcgcggcac gctcgccctc tgttatcggg
    15721 taaatctcca aagccgcatc gccagccgca ttctgctgcg cattgcggaa ggggcctatc
    15781 gcgacgaaca cgatgtctat gacgcagcct acgccatccg ctggcaggat tggtttaccc
    15841 cgcagcaacg catcaaggtg aaggtgagcg cgcaccgttg cccgctgaag agcctggatt
    15901 ttgtgacgct ccgggtcaag gatgcggtgt gcgatcgatt ccaatatgcc aggggcaaac
    15961 gcccgtccgt cgatacccat gcgccggaca tcctgattgc cgtctactta gacggaaccc
    16021 aatgcacctt ctatctggac acctccggtg atccgctgtt caagcgcgga tggcgaaagt
    16081 cctccggcga agcgccgatc agggaaaatc tcgcggccgg aatcctgcgt ttgtccaaat
    16141 ggacaccgga cgtgttgctg tacgacccca tgtgcggcag cgggacgttt gtcgtcgagg
    16201 cggccttgat ggcgggtcgc atcgcccccg gcatcggccg cggcttcgca tttgaaaagc
    16261 tgctctcttg tgacgccccg atgttgaatg acctgcgggc ggaacttcag gccgcggaga
    16321 ttcccgtcaa gcccgggttg attcacgccg ccgaccagag cgcgcaagcg atcacctcga
    16381 tcagagccaa cctcgcgctc gccggactca cggaggcggt aacgctgcaa cagggagatg
    16441 tcctgcagct tcccgcaccg gcggaggccg gcctgctcgt caccaatcct ccctacggcc
    16501 accgcatggg agacgatgag accttgaaga cattttatcc tcaattcggc gaccatttga
    16561 aaaaacactt ctgcggttgg accgttcaga tttttacggc cgacatgaag ctgcccggcc
    16621 ttttgcgtct ggcgccttca cgcagggtcc cgttgttcaa tggcgccatc gaatgccgcc
    16681 tgtttgaatt ccgcatggtc gccggcagtc tcaggaaacc caaaccacca gcacaatcct
    16741 ccccgggcca cggccaccac tgaccggttc tccgggcagc cgaatacatg cttgacagtg
    16801 gagcataagc ctcctatttt caatctatgt cattcgacgc gccatcatat ctgtgtcaca
    16861 caccatgcgg aactctatga gcgcagccca cgcgcccctt gaggctccgc agcaggagca
    16921 cgacctgtca ctctcgcgct tgatcgtggt ttcgaaccgc gagccctacg aacaccggtt
    16981 ggtgaaggat catctgattt gggaacgcac gtcgggggga ctcatttcgg cgctcgaccc
    17041 gatgatgcga cgactgggcg gaacgtggat tgcctgggga agcggcaaag ccgatcggga
    17101 tgtggtggac gaggatatgg tggtcgaagt tcctcccgac gctccgacct atcggttacg
    17161 ccgcgtctgg ctggaaaacg gagaggtgaa gggcggctat caggggtacg cgaatcaggt
    17221 cctctggcca ctgtgtcacc tcaccctgga tcgcgttgct taccggaaag cattctggca
    17281 tgcctatcag gccatgaatg cacgctttgc ggacgtggtc ctcggtgaac tcgccgaaaa
    17341 acccggcttc gtctgggtgc atgattttca tctcgccctg ctgccaggcc tgatcaaagc
    17401 ctccctgccc aaccaaccgg tcgcgatctt ctggcatact ccctggccag gcccggatgc
    17461 gtttcgcatc ctgcccgaac gccgggaact cctggaatca ttactggcgg ccgacctggt
    17521 gatgtttcag acggaaagct ttctgcactg ctttcttgaa tgcgccaaag aattcctcgg
    17581 caccgatgtc ctgtccgacg agcatcacat cgactataaa ggccactgca cgcgattggt
    17641 cgttcgcccc atcagcatca attatcaatc gtgggccgag cgggcacaat cgccgcaagt
    17701 cacgcgggcc atggacgtct tacgtaatct acacattttt cagccgaccg tacgcatcgg
    17761 actcggcgtc gaccggctcg actacaccaa aggtctcctg aagcgattgt gggccatcga
    17821 cgccttcttc cagcagtatc cgcagtatcg cggccatttc acgttcatcc agattgccgt
    17881 gccgacgcgc ggcgatgtgg aagcttaccg gagctatcgc gaactgatcc gcgaaacggt
    17941 caatgagatc aatatgcgct atggcacgat ctctcacccc ggtagtccac aggcctcgcg
    18001 ctggcgaccg atcgaatttc gtgaagggcg cattggtatg gataccctgg cggcctatta
    18061 ccgcatggcc gacctggcgt tagtgagttc ggtttacgat ggcatgaatc tcgtcgcgaa
    18121 agagtatgtc gccagccagg tcgaagagaa aggcgtgttg ctggtgagcc atttggccgg
    18181 cgcggcagaa gaattgaccg acgccgtggt gatcaatccc tacgacccgg aaggtgtggc
    18241 cgactccatc cgccaggcgt tggagatgcc atttggagag cgccgtgaga ggatgcgacg
    18301 catgcgcgcc tatctggagg cacatgacat tcgcgcctgg gctgatgact gcctgcgcga
    18361 cgcaggaatc cttccacagc aggacagtcc cgcccttgaa taatcgacgc ctgcccgcaa
    18421 ccaccgatcc gaagatcccg ttacgccgac acctcccgtt gttcctgttc ctgagcctct
    18481 cgatgctcct caacggctgc acacagctat ccaaactgtt cgcggtcacg ccgtcgccag
    18541 atcaacaagt ggatcgccac caacaggcga tagtatcccg gctcgcgcca gtcatcgaag
    18601 ctgaactgca agacaatctg aacgtcatgc taccgacagt tcgcaagagc ctcgccgatc
    18661 agacgaacaa ggtggcgaag ttcaagcgcg atctggtgtt gcgttcgcta tctgatccct
    18721 gggcgggcct cacctcgatc gagcaaacca gccttgtcgc cgccaccgcc gccgagtctg
    18781 gaattgagga actgcccgcc atcatcgaca ttttggaaga agggatggag cgaagcggcg
    18841 cgccgttcaa gcccctcaac tttccggcta ccctggcacc ggaggatatt ctcggtttta
    18901 tcatggaagc gcttgaagat gcccatcagg accgcgaaca ggcactccgg cacctgtctc
    18961 cgcaggatcg ggactttctc ttcacccagg cgcgtccgct tgcggaacaa ttccttccgc
    19021 aaatcattcc gccggccagg cttgcggaag ccgaagccgc cggccgctat gccgcgctgc
    19081 tcatgcaaca ggtggattac gcatcgctca ttgccgccgc acaacgatta gcacggctcg
    19141 gcaaccggaa attattgcaa caactggaca ttgcgctcca ccatcgaaag ccggtcaccc
    19201 agacggttcc cggcatcacg ggcgatctgc tgctggttca gcagacttcc tacggcttac
    19261 tcgtgatagg cggccatggc ccgaatacgt atgacctcga caagggagcc gcgctcatca
    19321 tcgatctggg gggcaacgac acctatcgag gcctcatcgg cgcaagcccg aacagcgacc
    19381 tgggcaacag tgtcgtcatc gacctgagcg gcaacgatct ctaccagccc gccccgctgg
    19441 gcttagccac tggacgcgcc ggtgtcggta ttctcatcga tcatagcggg gacgatacct
    19501 accggttggc acctggctcc ggtggcgccg gtttcgcagg gctcggcatc ctgtatgatg
    19561 gagaaggaca ggatgtgtac gaaggaagcc ggtttaccca aggcgcagcc ttcggcggat
    19621 tgggtctgct ggtggatcgc gctggcgatg atcgctatac gagtttcggg tacgcgctag
    19681 gattcggcgg gcccttgggc gtaggggcgc tcatcgatgt ctccggcaat gattcgtacg
    19741 aatgcggcgg aaaatacccg agcgcctaca atgaagcgga cgcgccgcat gctcgccctc
    19801 aggatccggc ctttcaatat gattgtttcg ggctcggcac cggggccggg cttcgcatct
    19861 acagcaagca gccggcgcaa cgggcgcaga gcctcgccgg cggatggggc ctgctggtcg
    19921 atctggccgg tcgtgatcgc tatcgcagcg ccaacttttc gcaaggacac ggctactttt
    19981 tcggccttgg cgtgaagctc gatctggccg gcgatgacga acatcaggcg gcgcggtacg
    20041 gcataggcac cgccgcgcat ttcggcgtag gcctgagcct cgactatcaa ggcaaggatc
    20101 ggtacggttc caaaggcccg ttctataacg gcggcacagc ctgggatggc agcgtcgccc
    20161 tggccgtgga cggcggtccg gacagcgatt tgtatgacct gcccgcttcg accggcctgg
    20221 gaatggcaga tctgggcggc ttgggcctgt tcattgaaga aggcggcgcc gaccagtact
    20281 tcatcggccg gggattagga cagggcgcag atacgagcat cggcgccttt ttcgacttgg
    20341 aaggtcggga tgactatacg tctgttccgc tgccgaacgg tgatgcgcga ccggaacggc
    20401 tgaatcgcaa aacctatctg gaaaataccg gcagtctctt cgtcgaccgt taaccggtag
    20461 ttttgccccc cgcttgactc cccttcctcc atggctatct caaagaacgg tgatcaacgg
    20521 gaacgaacat cattccttgt agccgattca tcttccttgt gatgaccacc tcagaaccgt
    20581 ggaggacgat atgactgatg cgaacgcccc catactcacg aacctgccga tactcccgtt
    20641 gaaacgaacg gtcctcttcc ccggcacgat gatgccgttg acggtgggac gcgaccgttc
    20701 catcgcggcc gtcgaagcag cgctcaaaac agaagacaag accttgctgg tcgtggcgca
    20761 acgggatgct cagactgatc agccgacgct cgaagacctg tatacgatcg ggacgaaagc
    20821 cgtcatcaag cagacggctc gaaccccgga aggtcattat aatattttga ttcagggact
    20881 ggagcggttc gtgctgctga agctggacca ggttgatccc tatctgcaag cgcgagtgaa
    20941 gcaattgcca ccgcccagcg aacggagtac ggaggtcgag gcattgcatc gagccatcct
    21001 cgacatcatc accgaactgc ccaaactgat ccagacacca ggcgtgcatg aagcggtggc
    21061 ggccctgggg accgaagaag accccgtggt gttggcctac cgcatcgctt cgttgttgaa
    21121 tctcacgctg gacggcgaac agcaactgct ggaagcgtcc acccgtgcgg atctgttgcg
    21181 cgggctgtac gccgcgctgt cgcgcgaggt tcagattctg caattgcgcg acaagatcac
    21241 cagcgaagcc agggaaaaac tgggcaaaac ccagcgcgag tacctgctac gcgagcagct
    21301 gaaaacgatt cagcaggagt tgggcgagag caacggcgaa gaagacgagg tggcggcact
    21361 gaggaagaaa gtgcaggacg ccgatcttcc tgagcatgtg agaaaagaaa ccgatcgcga
    21421 gttgacgcga ttggccaaaa cgcccagcgc ctcgccggag catcaggtca tccggagcta
    21481 tcttgagctg gtgctcgaat tgccgtggaa caaatcgtcg gaggaaggcc tcgacctcgc
    21541 gcatgtgcga aagattttga atgaggatca ctacggcatt aaggaagtaa aggaacggat
    21601 tgtcgaacat ctggccgtgt tgaaattgaa cccttcggcc aaggcgccga ttctctgcct
    21661 cgtcggccct cccggcgtgg gaaagacgag tctgggacaa tccattgcaa aatccatggg
    21721 ccggacgttc gaacggttca gcctgggcgg cttgcatgac gaaggggaat tgcgcggcca
    21781 ccgccggacc tacgtcggcg ctttgcccgg acgtattatt caagcgatgc gacgagccgg
    21841 tgtgaacaat ccggtcatca tgctggatga ggtggataag ctggggcgtg actttcgcgg
    21901 cgatcccgcg gcggccttgc tggagattct ggatcccgcg cagaaccata cgttccggga
    21961 ccattacctc gatctgccgt tcgacttgtc gaaggtgttc ttcattacga cggccaatac
    22021 gctggagacc ctctcgcagc cgttgctcga tcgcatggaa atcatccggg tgaacgggta
    22081 tagcgaacgg gaaaaacggg agatcgccct gcgttatctc tggccgagac ggctgaaaga
    22141 ggctggcctg aaagcagaag aagtcaattt gcccgacagc gtgctcgacc atatcatcgg
    22201 ccggtacacc agggaatccg gtgtgcggca actggagcag atgttaggtc gcattacgcg
    22261 gaaagtggcg gtgacctttg ccgatcggcc gtccgattct cctgccgcgc cggtcgaaat
    22321 cacccaatcg ctcctggatg aatggctcgg tcaggaacga ttccagccgg aggaggcgcg
    22381 caagaatctc ccggctggtg tcgccaccgg catggcctgg acgccgacag gcggcgatgt
    22441 gctctacatc gaaacgaccc tcctacccgg cagtcacgag ctgacgctca ccgggcaatt
    22501 gggagacgtg atgcaggaat cggctcgtgc ggcacgcagc tacctgtggt cgcatgcgga
    22561 gagcatggga ctggacatct cgcgtttcaa acggaacggc gtgcacattc acgtgccctc
    22621 cggcgccatc cccaaagacg gcccctcggc cggtattacg atggcgacag cattggcctc
    22681 ggcctatgtc ggcaaaccgg tccggagcga cacggccatg acgggcgaaa tcagcctgac
    22741 cgggctggtg cttcccgtcg gcggaatcaa ggagaaggtg ctggctgccc atcgcgccgg
    22801 catccggcgg atcattctgc cgaaggctaa tgagaaggac ttgaaggaag tgccgcaaga
    22861 agttcgggat gaactgacgg tcattccggt cgaacggatc gaagaggtcc taccggcggc
    22921 gttcaaccag gatgcggcct cgtcgccgga gaaacacgaa ccgatggcga cgtccaccgc
    22981 atcataagct ctcgggcccc ggctgagaag ccggggcccg ctcagcgacc gctttcaaac
    23041 tccctctacg cgttgaaggt cactactcgc ccatccgatc gccttgccct tccgtaaaga
    23101 catatgtcag gatgaaaaac gtcacctggt tgatgcgcac cgcacatgac ccggcaaagg
    23161 agaggatcca tgccatcgaa catcgagatc ggaccgatcg tgaaggtgaa caagaccgac
    23221 gacgaatgga aaaagctgct gccggctgcg gcctaccgtg tcctgcggca cgaagatacc
    23281 gaacgagcgt ttaccagtcc gctgcatgac aaccaccagg ccggcatcta tcactgcgcc
    23341 ggctgcgact tggccgctta ctcttcagac cataagttcg atagcggcac aggttggcct
    23401 agtttctggc aacccgtcga tccgaaagtc gtggagacac gcaccgatac caagtttttc
    23461 atgacgcggg tcgaagtaca ctgcgcgcgc tgcggcggcc accagggcca tatttttgaa
    23521 gacggtccca aacccacggg attgcgatac tgcatcaacg gcgtctcgtt gaaattcgtt
    23581 cctgcctgaa cacgatccgg gcatgtctct ggattatggc gacgacttcc gctgtcgtcg
    23641 ccgatcgtga acatctcttg agcgtctcat cgcaccttgc aatttatcgc tgaacactcc
    23701 tagactgtga attccatggc ttctctccct tcactacgct cgacgatggc cgccctttgg
    23761 ctgggcgtca cactgctcgg gtgttcccaa tcgagcgacg tcatttcgaa caatctgaat
    23821 gcctgcctca tcgtgaccga agccgaggtt gaattcgcga tcggcacgcc ggtgaccccg
    23881 ggcctgcgcc agaatgatcg tcaatgtctc tatcaggcaa agcgcaaccc gcaagagacg
    23941 gtcgtggtgg aactgaatgc cggtccggat ggggatcgca aaactctgtt tcaggatcaa
    24001 cgttcaaaag ccggcaacca gccggtgccc ggcgtcgggg acggcgcgtt cacgcttcgt
    24061 tctcccatcg gaggcattca gctgaccttt ttgaagtcag atgcgctggt gacactctcg
    24121 ctcacgtccc cgaagcaagc caatccacaa gcggccgtca cgaaccttgc caaggtcgcc
    24181 gccaacagac tgggcgctcc gattcgtacg actgccgcgg ccgcggagcc gggaatcacc
    24241 ggaaccccct cattgtgggc cggtgaatgg tacggctgca tgcccgtcgg catgatgtac
    24301 ggcaaagggc atctctcgct gaatgaacgc ggcacctggt ccatgacgac cgccgtcgtc
    24361 atgccaggca ccatcatcgc ggaccgcggg cggtgggagg cggaatcgta tcaggaaatt
    24421 cttcacggca cctacaaagt agccggcagc gaccggtttt cgaccaccgg tattttaagc
    24481 gtgacctggg acaagctggc gaagaatcaa ggaccgacca agttcgatcc gctcctctgg
    24541 caatcgttca ctgcgattcc caggaaggtc aacgtcaaac gtctgccggc ggtcgaaccg
    24601 tccctggtgg gcacatggga ggggtcctcc aagtttgtcg atcggcagga agattttgtc
    24661 tggacgatca ccgcagccaa cgtctccgag ttcttcaaag ccacgtcaca aactggccgc
    24721 atcgagcagg aacaggaccg gttccgattg gtcgttccgc aaagtaaaac gccgcctctc
    24781 tccgtccggg tcctggccca ggataaaatg gaactgaccg acacgagcgg cacggtgtcg
    24841 caatggaatc ggaatgaaaa gctgctgtcg cgctgttagt cctcttcagt gacaaggccc
    24901 atcccttcca gggccggcag actttttcgc aacttgacct gcttttcccg cctccgatag
    24961 actaactcta tgcgaacatg gctcatcgcg ataatctttc tcgccggacc gctgctaccg
    25021 gcagcggggg ctcctgtcgg agcagccgca gaccgcccca cccccaaggc aagcgagttg
    25081 ctggacgaga tcattccaaa agaactcttt cgccacctct acagcgaagc cctctccaca
    25141 ttgcacgaat acatcgagat ggaaggcaag ctgcccggtg agagttcgac ccatcaacag
    25201 gggggagagt ttcgcctcaa actgtttcct cacggcaaat cccgatcaca agaacacctg
    25261 agcgcggaag gctcgtttcg tgtggcaccc gaggccgacc aaccggaatt cacccttcga
    25321 ttcaaatcct tcaagaaagc ctcgcctccc gcacgcacca atgacgacgt gatctgaagc
    25381 ccactcccac acgcacgcgt cgccgacctt gcccttgacc aaggtctgag cggggcatag
    25441 aatacatttc tagtacacga tccgcctcat gtttggaggt cggagccatg ttcttccttg
    25501 ggacgcagat ccagtgggat gaacatggta ggtgtaccct gctcctcgac caaacctctt
    25561 ctcttaagac cgccgagtta caagcatcca cacaacacat tcttacgcgc tcgcgtacct
    25621 tcgctcttca ccaagcgtta atcactggta cggcgacacg tgcacagagg actcgcgcga
    25681 tacccgcgcg ggagcgtggc ctatgtcagg agtctattgg ggaatcgtgg caggtttcct
    25741 ggcgatgata ggaactctct tcgcctgtat agacattctg tatggcgcac agggaggctc
    25801 gtccaattcg tcagcagatg gagtcgatac gtcgaatcag gcggtcggat ccgcgtcgtc
    25861 cggctcgcgt cgggcagcgt gagggcgtcg cacgtctgat agcctcgtgg atgagagacg
    25921 ccatggatgc tgtgtcgcac agagggctcc atcggcgtcc cggccaacaa tctgttgttc
    25981 aacaacggag gtgccacatg gaggtcgaga tcatcggtgc cggaacaatg atcgcgctgg
    26041 tgtggctgat tgcctggtcc atggctggag agagcgagtc ggaaagacga cggatcacct
    26101 cggcgcctgg cacgttcgac acggcctcgg gcgaaacgag agtgaggcac gcagcctaaa
    26161 cgaagcttcg gttgtgcagg agatacgtgg tgtatcccgc ctattggcgg gagcggcgcc
    26221 tgaggaatgg tgtgtgcgcg ggattgccgg accaagaatc gatagttgga tgtgattgtc
    26281 aggcgagaat cttcggctgc ccgatgccgg cgatcacctc ttcggtgatg acgacggact
    26341 tgacgccact taatgccggc acgtcataca tcagatccag catcacttct tcgagaattg
    26401 tgcgaagcgc tcgcgcgccg gttttcatca ctgcagcccg gcgagctacg gccttgatgg
    26461 cagcctcagt gaattggagg tcgatgcctt cgatctcaaa gagagcctga tattgtttca
    26521 ccagcgcatn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    26581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnt ggaggtcgat
    26641 gccttcgatc tcaaagagag cctgatattg tttcaccagc gcatttcgtg gctcgctcaa
    26701 cacccgaatg agcgccggca cgtcaaggtc ggccagggtc gtgaggaccg ggaatcgacc
    26761 cacaaattct ggaatgagcc cgaatttgag caggtcttcg gattgcacac atcgcagcac
    26821 ttcactgtgg ccctcgagtt caccggcagg agcgattgca ccgaacccca accgcttggg
    26881 catcgtccgt tgagcgatca tggcatccaa cccgacgaac gccccgcccg cgataaatag
    26941 aatgttcgtc gtatccaccc gaatgtagtc ctgctccgga tgtttccgcc cgcctttggg
    27001 cggcacattg cacaccgtcc cctcgaccag cttcaagagc gcctgctgca caccttcgcc
    27061 ggagacatct ctcgtcaggg acggattctc cgacttgcgg ctgatcttgt cgatctcatc
    27121 gatatagatg atgcccgttt cggcccgggc aacgtcgtaa tcgcaatttt gaagcagctt
    27181 gaggaccaca ttctcaacat cctctcccac atatccggcc tcagtcagtg ccgtcgcatc
    27241 ggcaatggta aaggggacat gaaggatacg ggccagggtc tgggacagca gcgtcttccc
    27301 ggtcccggtc gagccgatca tgaggatgtt ccccttttcg agatcgacgt gcttgagccg
    27361 ttcccgattc acaatccgct tgtaatgatt gtgcacggcg acggagagga ctttcttggc
    27421 acggtcctgc ccgatcacat attcatcgag cttggccttg atgtccgtcg gcttggggat
    27481 gaccagcgga agcggtgaga ctgaggattg ggaaccagga gttttgttct tggccaggga
    27541 aagggagcag cgttgaatac attcttcgca aatagaaacc gctgccgggt tcctacaaga
    27601 ggtgcacgcg aacggctctg aattcgtcac gagcgtccgg ccggcgtcct gaggcttgcc
    27661 gcaaaacgaa cagcgccggt ctggtttctg cgtcgaatgc cgcgtgtccc agaacaccgc
    27721 gtttcctcca tgctacgaga tgtgcctgga tgcgatgcct catcttatgc ctctgtgatg
    27781 gcgacctgca agcatggagg aatcacggtc tcagcgctga acggcgcgac gagcgcctgc
    27841 cggaggatga ccacagcctg ctagaaggtc acgccaaacc caccggcaat gatatgggta
    27901 cggtagttca gggtgaaaga gggacctcgg gagccattcg tgaattcact ctcccattgg
    27961 taattcgcca cgaaatattt gtactccgtg aagaggaaca ggcggtccgt gatgttggca
    28021 cgaacgccgc cgagaaattg gtacgcgaag gcgccgtcgg ccgcattttc atgcacggta
    28081 ccaatcgtgc tgtgctgaag gttcaaatct ctggcgaatc cacctgacaa tcccgctccg
    28141 attccgatat agggctgaat cacatcgccc ggataacgca gtaacaagtt ggccatagcg
    28201 ttaatcgatt gcagacggaa attagcagat ctcgtcacgc ccccgctcgt cgccgtcggt
    28261 gcgttcactt ttccgtcgag gcccgataac tccgcttcca acccgacata ccgcccggca
    28321 aacgccggaa aaaacccgat cttgagtcca ccgcctaacc cgccctgaac atccgtattc
    28381 gtgaacgggt cttcttgcaa gcgggcggga cgattcagcg gccggcttcc ctgcatgtag
    28441 aggctgatgt acagttccga cttagtctct tccgcctttc cctccgctga tgccgacggc
    28501 gatttcacgg cattcgccgc agggtctgct gcgagcaaca gagcgggata gacctgtagc
    28561 aatacaccgg cgagaacaac gacgcccaga gaccagaatc gtgatttcat gagtgactcc
    28621 tccgagtacg tggcaagaca ggcccagaac ggcctgcgat agctcactca tatcacgagc
    28681 aaggtgcgcg acaaactgat tcggcagttt cggcagccgt actctctgtc tgtacgtatg
    28741 gtggaacttc gtacgtaacg aatgggttgt cacgagctgg cgaggaactg tgtgagagtt
    28801 tcaggtggaa ccagacccac caatacctgt ccatcagccc gttgcagcaa gggcacgccc
    28861 tgatgttctg tctcttccca gcgatctctc cattccccga gcatcgactc tactgcaggc
    28921 gcggttgatc cgaacaatgc ggttccgacg aacccctggc gttccgcctc cagccgtaac
    28981 agacgctcat tggaaagatc caaaccatct acccagaaca gacgatacaa cgaccggatg
    29041 aactcgcctg ctcgccgagt atcctcgcgc agcgcacgcg cggccaccgt aatggctaat
    29101 ctggtattcg gctttcctgc cggcactgag atgggcaact caggcgcgag ccgacggacc
    29161 attttcacct cctgcttcaa ctccgcatgt aaatgtccgg cccaggtggc catgggctga
    29221 ggcaagtgag gggcatgctg cacaccatgc cacgatatct gttcgaggaa accgagcgca
    29281 tacagccgct catgcatcgc ataacaaaag gggcagttga agtcgctata cacacgacag
    29341 gaggtttttc tgctcgtcat ttgccgtccc gtgacggaag aatcgcgatg atgcggaccg
    29401 gcgccccggt gcctcccgca atcttcatcg gcagcgccac cagcctggcg cccgatgcgg
    29461 gaacctctgc gagacccgcc acattctcaa gcccgtagag gcctgcggca ttgacgatcc
    29521 ggtgcacgac aaaatcctga gagggcccgt aatcgatact ggccgtatca atgccgattc
    29581 cggaaatgtg ccgttccctg acgagaaact ccgccacttc cttggagaag ccgggaaaat
    29641 gcagcgtggt tggaatctcc ggcgtcgcgc tgccgaaata tcgttggcga tcattccaat
    29701 aggcgcccca gccggtcagc atcatcacga tggcgcctgt cgggatggtc ccatgggcag
    29761 cttcccagcg atgaatgtcg gcgagagaca ggcgatagtc acggtcatcg gccgccgctg
    29821 cgcgcacatc gatgaccacc gcaggtccca tcaactgctc gaccggaatg ccgtcgatcc
    29881 ccgcttggcc ctgcgcaaaa tgaataggcg catccatgtg tgtacccgca tgctccgaca
    29941 gggccacctg tccggtggca taccacgctt cggtggtggt gccgcctcgc tgcgtggagt
    30001 cacgatgaaa cggaggattg ctgggccaca cctgggtcgt ctcatcgaac ggataggtca
    30061 ggtcgagcac tcgtggtcct atctcggcgg catgagaccc gcttacggcc gacacgtgca
    30121 tcaccacaca aagcgtcaac gccgacaatc cgagccaacg tagatgtctt ggttttatca
    30181 ccatgtttcc tcgtcctagg agtgagtgcc cccggagctt tcgtacaggg cgcgattacg
    30241 gtaccctctc acccctcagt agcgcaacgg ggaaggaacc ggtatgtcgg atcagcagct
    30301 ccatttttcc gggcaacgtt tttctgtgga atatcacatt cagggcacga aagaggaggc
    30361 gtgccggcgc gccgctgtcc tctgcatcga tcagaccgtc gaagccgcgg accacgtgat
    30421 tccgtcgggt gtgattcgcg atcagctgct cggtcagatg ctcagcatcg acagggtcgg
    30481 agacggcgtt caccgcgcga cgctcacatt tccgattgaa ctcctcgatg gaaccatggg
    30541 cactctccag cacatgagct ttggcatggc gggcctgcaa agccgggttc gcctggccaa
    30601 tctgtcgctt ccggatgagg cgatcgccca gatggctggc ccccgcttcg gatcactgaa
    30661 acttcgtgcg ctacttgaag tgcctgtgcg ccccttggtc tgcgccgtac tgaagccact
    30721 cggcctgtct gcccgcgcgc tggcaagcct ggcttacgaa ttcgcactgg gcgaagtgga
    30781 cctcattaag gatgatcaaa gtctcggtga ccatcctttc tgccgattcg aggaacgtgt
    30841 gactctgtgc gctgaggcca ttgccaaggc ttcccggcaa accggcaggc gctgcctcta
    30901 cgccccacat gtttccggcc cctggccgac gctgctcgac cgggcctccc tcgcgcagaa
    30961 cgcgggcgcg ggtgcgctgc ttctctgtcc cggactcaca ggctttgacg cactcggcac
    31021 tcttgcccgt ctcccattcc cctcattacc cctgatcgcg catccggact tccaaggcag
    31081 tcacttcgtc aactcagcca ccggtatcgc cccggcagtg ctcttcggtc ttttcccgag
    31141 gttggccggg gctgatgtgt caatttatcc caccttcgga ttggagtatc cgatctcgca
    31201 agaggattgt cggggcatcg ccgcctgctg ccgaaacagc ctcggcgcct gtgccccgat
    31261 ctttccgacg gccgcaggaa gaatggaggc ctcgcggatc catgagatgg tcgccttcta
    31321 cggaaccgat gtggtctttg tcctgggcag cgacctacgt cgagatccga ctcgcatccg
    31381 aagtgcctgc caggaattta ttcagcttct cgaagccgag gtggctccat aactcacatc
    31441 tccacttcta ctcaatgtat tgcatgcaac atgttgttat gcatcatgtt ttatccatta
    31501 aaaaacttgc ttggcactca tcttttcctg accgtcttca ttgccattgg caagataccc
    31561 gggaaggtca cagggatatc cccttgattc atcaagtttt ctatgccggc caccgataca
    31621 ggccataacc tgaagtacgt atgcatagtg agcctccgtc cgtgtttggg caatcatggc
    31681 cttagctaaa acatccgacg actccagaaa actcgataag tccgacaccc tcgtgctcag
    31741 ccccgagcgc cttcgtgtgg ggatgtatgt tgatctgaat tgcggctggt tcagacatcc
    31801 cttcccccga cgctcgttta aactcagctc tgcgagccag atcgccacga tcaaagggct
    31861 tggactcact accgtcctgg tttacccccg ggaatcagat ccggacccgg acgcagaggg
    31921 aacgctgcta gaaacggatc cggcgtccac ggcgactgtg gaaccggata cgggatctgc
    31981 tccggcagcg gccgctgccg atacgaatcc tcccccctcg gacgaagagc ttcccacgca
    32041 tggcgactat catcaggccg tagaattggc ttctgaaacc taccgccaga tgctcgggac
    32101 cagtaaagac atgatggacg cgctcacaag cggatctgag gaaggcatgc gttccgcgga
    32161 aacgatgatc ggcggcatca gcacgctctt gacccatacc caggccgccg gcaccgtggc
    32221 gagcgccttc gaccccgaag aaatcggcga tgcgggtgtg ctccactctc tgaatgtcgc
    32281 caccctctcc atgatggtcg cccagcaatt tgacatcgac caggacgccc tacagatgat
    32341 cggcctcgct ggcctcttgc tcgacatcgg cgagcggcgt atcccgcgcc atattttgga
    32401 tacacgcgcg cgacggtccg aaacggaaca tgtcaaatac cagctccatc cctatctcgg
    32461 cgtcgagatg ctgcgagggt ttcctggaat tcccgaagag gtgctggacg tgatccgcag
    32521 ccaccatgaa cgtctggatg gatccggcta tcctgaaaaa ttgaaagggg accagatttc
    32581 attcccgacg agaatcgtca gcgccgtcga tcactacgat acgctggtga acagtctcta
    32641 cgccgaagag gcgctgtcac cggccgaggc gctggcgacc atgtacaagc atgaaaaaca
    32701 gctgttttcg accgaggtcg tggtggccct gatccacacg ttgggcgtct atcccccggg
    32761 gaccgtcgtg tccttgtccg atgggtcatt cggcctcgtc ctgaacatca acttcaagaa
    32821 tcgcatgaag ccgttggtat tgatgtatca tccgactccg ggtcaggaac cccatacaat
    32881 cgatctgctg agagaccaaa cgctcagcat tctccgtgcc gttccccgcg aggaactccc
    32941 ccgcccgatc gtcgaattct tccggctaaa acggtggacc gggtatttca tccaggccac
    33001 catgcgcacc gcctgatgca ctgaggattg ccaagcctga tcactggcag cggcgcggtg
    33061 cagtatggta tctccctggc atggccctac cccgtgtgct cctgatcatt cccccattaa
    33121 cgcaattgaa cacgccgtat cccgcaacgg cctatctcac aggtttcctg cgatcgcgag
    33181 ggtatgaagc ggagcaggct gatctcggtc tcgagatgat ccttcgtctc ttctcgcgag
    33241 ttggacttca ggaggcgttt caccgcatca aggccagccg aagaccttgg cgcggagagg
    33301 tgcagcaatt cctggcgctc gaagacagct atctggccac catcgacccg gtcatcgcct
    33361 ttcttcaagg aaaggatccg atgctggccc cgcatctcgc tcgcccggga ttcctgccgg
    33421 aaggtcctcg cttcggcgcc gacgggcgac cgggatcgag ccctttcccc acttctccaa
    33481 ccgacagcgc ccgtcaccgc gcgacgctgt acctggaaga tttgacggac ctcctctacg
    33541 aaaccatcgc gccccattta ttcctgaatc gttacgctga acagatcatg caagcgacgt
    33601 cctccttcga cgggatagaa aaggctctgg ccgaaccact gagctttacc gacgaactcc
    33661 tgctcgaggc gctcgcgccc cttctggccg gcagttcgcc ggatgtcgtg ggtctcaccg
    33721 tgccgtttcc cggcaatctc ttcggtgcct tgcggattgc tcaagccatc aaggcacagc
    33781 ggcctgcgac tgccgttgtc ctgggcgggg gctatgtgaa cacggagctc cggcgtctca
    33841 aggatccacg actgtttcga tacgtggact acgtcacgct ggacgatggg gaacgcccgt
    33901 tcctctgcct gctcgacttc ctggctggtg gacggtcaca accccatctc tgccggacat
    33961 ttgtgctggc cgacgggcag gttgtatttc gaaacggcaa tacggagccg gacctatcca
    34021 tgcacgaact cgggacgccg acctacaacg gactcccgct cggccgttat ctctcgatcc
    34081 tcgacagcct caatcccatg caccggctct ggtcggaagg ccattggaac aaactcaccg
    34141 tcgcgcacgg ctgttattgg aaacaatgca cgttctgcga tgtggggctg aactacattg
    34201 cacgctatga gatgacgccc accgatgtcc tgatcaggca gatcgaggcc ctgatccgag
    34261 agacaggcca gcgcggtttt cacttcgtcg acgaagccgc gccgccggct gcactgaaag
    34321 cgctcgcact tcgcttgctc gaaacgaatc agaccatttc ctggtgggga aacattcgct
    34381 tcgaggaagc attttcaccg gacctggcaa gactgttggc ggcttccggc tgcatagccc
    34441 tcacggccgg acttgaagca gcctcagacc gtttactccg gcaaatgaaa aaggggatta
    34501 ccgtagacca aacggccaga gtcgccgcgg cattccgcca tgccggcatt ctggtccacg
    34561 cgtatcttat gtacggcctg ccgggtgaga gcatcgccga cacggtagac tctctcgagc
    34621 gtgtccggca attatttgca aacaatttgt tgcagtcggc attctggcac cgttttaccg
    34681 ccaccgccca cagccccgtg ggactcaatc ccgccgccga gggtatcacc atcctcgggc
    34741 caacatttga agggtttgcc gagaacgatc ttcgccatgc cgacccgaat gcctcctgcc
    34801 cgccatggct tggcgagggg ctccgcacag ctatcctcaa ttacatcgaa caggcgggac
    34861 tgaccgtgcc ggtccaacaa tggtttccac aagccgtaca agctcctcgc gtggcgaaaa
    34921 catggctgac acgggccctg gccgacgccg tccctgaacc attgaccgcc gagcggcggt
    34981 gcgtctggat cggtggacgg cccgtcgtgg cggcaaaagg caccacgcgc gtgaagatta
    35041 ttctgccgac ccgcatggaa gacttctcga tcagtgtctc ctcagatcag gtcgactggc
    35101 tcatggatct attgcagaac gccagtccct ccctgcaccg cacagaccgc gactaccccc
    35161 gcttcgccga ggcgagggag cggtttcccc acaccggcgc acgcggattt gatcggtttg
    35221 ccaggactgc tgcctggcat aacgctcgcc aggctgggct gctcctggtc tgagtcgaag
    35281 ccattcgcat tcgcggtcca ctccctacct gtttattcac aatcagaacg gcgacgcctc
    35341 ctaccacgga gcactcgctg catcattctg agacaggtgt tcgatgctga tacggaatct
    35401 gagcatccgt gtagtacgta ttagtatttt gatgtagcgt gtcacgaaat gcgaattacg
    35461 cgttgacatt catacgtatc tcaactacat gtgttctcta cgtatcacat attttacgga
    35521 ggacacgtat ccatgatgac tcctcgattg ctaacccttt tgatggcgac cggcatcgtc
    35581 tgcgccgcgc cactttcggc ttcagccatc gccgtctatt catcctccgg ctcgaatgcc
    35641 gcgtcgattc aaggttctgt cgatggattt cgggctgatc tcgggacaaa taacctggct
    35701 aatgccccgg caaccggcgg acgccgcgag attaattggg atggagtgcc tgctggtttc
    35761 tctgacccga atcacctacc cggcaacttc ttcaactcca actcgccacg tggcgccgtg
    35821 ttcgagaccc cggggtcggg attcaaagtc agcgcaaaca ccggcgtcgg aacgcccgaa
    35881 cgtttcggca gcatcaatcc ctccttcccc tccagctttt ccgtcttcag ttcgcagaaa
    35941 ctgtttaccg ccatcgatag caatattgtc gatgtgaagt tctttgtgcc cggcaccact
    36001 caggcggcca atgttcgcgg gttcggttcg gtcttcacgg atgtcgatct cttaggcccg
    36061 accacggttg agttcttcga catgaacaat aacctgctct cgaagcagac cgtgctcaat
    36121 acgcccggcg ccacaagcct gtcgttcctg ggtgtgtcac tggagcaagc catcatcaat
    36181 cgggtccgca tcaccgcggg aaatgccgcc ctctcgaatt tagacggctt cgactttgtc
    36241 gcgatggatg atttcatcta cggcgaaccg caagcggtgc cggctcccgc tgccgtgctg
    36301 ttgcttgcaa gcggcttggc tgcgttagtg tgggcacggc ggaattctct gctcccggaa
    36361 tagttttcag agattcgcct ctctcaaaga caagggggga gtcggtacta tcccgactcc
    36421 ccccttgtct ttcttcctca aatgtactga ctcaagctgc tcaggcgctc aaacgtcaag
    36481 aggagccggt ctgtcgaccg actcctcttg ctgtgcgttc gaaatgcagt gactgctgcc
    36541 gctacttgtt gggttgcggt gtcaggcgca gatacggctt caccgacttg aagcccttgg
    36601 ggaacaaggt cttggcttcc gcatcgttca ctgccggggt aatgatgcaa tcctgcccgt
    36661 ctttccagtt gaccggcgtc gccactttat acttggcagt cagttgcagg gaatcgacca
    36721 cccgcagcaa ttcatcgaaa ttccttccgc aagacgccgg ataggtcagc atcaacttga
    36781 tctttttgtc aggcccgatg acgaacacgg atcgcaccgt catgctgtcg agcgaattcg
    36841 ggtggatcat atcgtacagg ttggcgacct tcttttcagg atcggcgatg atgggatagg
    36901 tcacggtgca gttttgcgtc tcgttgatgt ccttcatcca cccgcgatgc gaatcgagcg
    36961 ggtccacgct gatggcaagg attttcacgc cacgcttatc gaattcgccc ttgatgcggg
    37021 ccatgtagcc caattccgtc gtgcagaccg gggtatagtc cttcggatgg gaaaacaaaa
    37081 tcccccaccc gttccccagc cactcatgga agttaatcgt cccgtcagtg gtttccgctg
    37141 taaaattcgg ggcatcgtcg cccaatcgta atcccatgat ttccctcctt aggtatcccg
    37201 tcaaacgtgg tgaaataact gacacatgaa agccgacaat ggcgtaagac taccgtttct
    37261 gagcggcgag gcgcaagcag gaagggtact gacatgcact gtcggataat cacccctctc
    37321 tcaagtttcc gctcgtgcat ccgataaggg acacaggtgc caaaggagtt cgcatggaca
    37381 acatgagaca acctgcgacc ggactcagga ttgccaacga tcccatgtac cggttactcc
    37441 gcgaggggtg catcaaggaa tttaatgtca aacgtgcggc gggggaaccg gtcgacctca
    37501 cgcgttgcga cctgcgcggc ctggatttgc gcgggctgga agtcgatggg ttggacttca
    37561 gcgaatgtta cttcaggcag gcggaccttc gcggcatcga tttccgcaag gccaagctgg
    37621 aaggcgccag catcaacgcc gccaaaatct caggtgccta cttccccatc gaattaaccg
    37681 ccagcgaaat cgaactgtcg ctcctgcacg gcacgcggat gcggtaccag cccaaaccct
    37741 agcctgcacc gatcagtcag cttccggtca aactgagatg cacccgaatc tgcggcttgt
    37801 ccgatgccgc cagttcggcc tcgaccaaaa atacccgttc atccggcaag tgtccctgcg
    37861 cgatcagatg ttcgcggatg gctttcgccc gctcctgggc caaaccacgc agttcagcat
    37921 cctctaccgt catggccgga aagagctgct gccggagttc gtcggccgtc aacacccgct
    37981 caacggattt tcctccggga agctcctccc gcttcatggg ctgcttgccc aacttctccg
    38041 catacaaatc actgagcagt tcgaattccc gcgagggaga gggcacggct tgcaggtttt
    38101 tcgtccctcc cttcgtaaac cgccgcagga cttcgtccgc aatcttctgc agggcaaggg
    38161 cctgtcgatc tcgcacggga tcagccactc ccgtgacatc tacccggagc gccggccgct
    38221 cttctaaggc tttggcaatt gactccagct tccgctgttc tggctccgca aggctgtcac
    38281 ttcccgcctg aaactccaca aactgtaggt cctctccccc gccgccgacg agtcccccca
    38341 aggccgaaaa cggagaggtg acgactttgg tgagcaggtt caccagggcg ttcaggacga
    38401 cccggccgta ccggaaatcc ggttcgttca aatctcctcg caccggcata tcgatatcga
    38461 tccggccccg ccggtctttc aagagaccca cggccaagcg aaccggcagc gtcgtggcat
    38521 ccgggctgtc ggttttgtct ccgaacgtca actgatcgac cagcacctta ttttccccga
    38581 ccaattgctt cttggagatc tgatacatga ggtccagcga cagtttcccc ttggtgatag
    38641 gatagcccgc gaacttcccc gcatagggtg acactgacgt caaatccaca ccctggaaca
    38701 caaacgtcag atgcgtaaag gtgtcttcac tgagtggatt gatctggccc tggatcttca
    38761 gcggggcaac ctcgtcgact ttccccgtca aggccacctc agccttggcg atctgccgtg
    38821 aagagaggcc tttgatggtg ccggtcaggt ctgtgattcc cgtgctcaca gctggaacga
    38881 tcgattcatc gctgaacgtc gccgacaagt tcgtcaacct gacgacagcg atctcaacgg
    38941 gagtcggcgt cgcgggcttc tttggggcct ccggctccac gggcttcgat gctggtgccg
    39001 gcggggtatc ggatggacgg agtactcgtg acaggttggt actcccgtcc ttatcggtga
    39061 tcagccggaa cgccggatct cgcaacgcaa tctcgccaat ttttaccgtg gtgggcgcca
    39121 catccagcgc catcttgctc aggctgagcg ctgtccaccc gagaaactct ttcgtcgagg
    39181 cgcggtcggc tacgtgaaga ttgttgagcc cggcttggcc tctgtactgc aacattggct
    39241 ctgattcgtg gcggctccga tagacgaggt ctccgtccaa catcaattca ccgtccctga
    39301 cctcgagctg aacgaaccga tccagatagg gttggaaggg ccggagaccg atatgatcga
    39361 gcttgagcgc cagcgccgct tgaagggaat cgaggcggag tgttcccttg gcttccaagg
    39421 cgccctgctg attgagtcgg aaaccggccg tgaccggcac cgcgccctta aatggcacat
    39481 gtacgtcgcc cgcggtcaga tgcacatcgt cgagcagcag ttcgaccggc gtcgcgaggc
    39541 ttcgatcttc aaaggccacc tgggtattcg cgacctcaac cgactgcacc gccactttcc
    39601 acgcttgacc tgcatccggc gcaggaggct cagacggtgg cgaagcgtcc gccgtggcgg
    39661 caaccggcgc aaacaggggt tgaaagttca ccaccttatc ctgcccgagc cacgcccgaa
    39721 cctccgctcc ggtcaatgcc acagtgccga ttcccaactc ccgcttggac aaatccatgt
    39781 tgatgccctc tatgccgaac gagggcacgg tcaccaccgg atctcgactc cccgcttcag
    39841 atagccggaa atccgccaac tgcaccttgc cctcggtcac ctgcaagtta atgggggcaa
    39901 gatgtgtgtc gaagtgatat cggacatcga ccaataatgt cccactcaag atatcgaatc
    39961 gaaaccggtc acgaagactc ggccaaaacg tttttaagcc gacatgcgag agagagacat
    40021 gtccatccga ttcgagtgga tcgaggtgca aggtgccctc ccaggccagc acttcacctt
    40081 ccccgaactc cgccgtaaac gcgtaggcgt tttcgcccct ccccctgctg gtgaagttcc
    40141 gtaccgaaat ttcaatgggc acgacatcga tggtcaccgg ccgtttcttg gaatcgtccc
    40201 ggtactcaat cacgccacgc tgaatactca gctgccgaat ctctatggac ggcatcggtt
    40261 ctttacgagg ctgctccacc ggtggtgcag gccgctcggc ctcttgggaa ccgggtggca
    40321 ccaggccaag aagattaagc ttcccgtccg cctgcagatg cacgaggcca aacggaagcg
    40381 tgagacggat ctcgtcgaac aggtatgacg agcgaactaa cgaggtggct tcaaagtcta
    40441 caaacaattc ctgaaacccg atcatcgggg tgtggtccgg ctcctgaatc tcaaaaccgg
    40501 tgagctcaat ggaaaaggta aacggattga gccgcatatc gcccaagacg acgggatgaa
    40561 ccaaccgttc agataaagca ggaatgccgt aggttttgac tgcgtagggg gcgacgacaa
    40621 aacctagtag cgcatacaac gccaccaagc cgctgagcac atacaggaga agtcgatagc
    40681 gggagaggaa cgtcatgtca ggcacacatc aggaaggtgg gggcaccggc tggaatcgag
    40741 ccagcaaccc tctgcttgca aagtcctttg aactgcagcg tgagtaaagg gatcgaatgg
    40801 gaaggataac tactaagacc gcctagaaca aggagaaaat gtctcatgga ttacaactac
    40861 gtgccatcca gacactgtca accggggaga aacatcggta atggagcgaa tgttgagggc
    40921 ttgtatgcac catgtcgatt tgcgaaccgg acgacgacta ctaggtgaag agtggaatat
    40981 acaagaaagg agaaatcata tgcgcttctt agtactcatg atcccaggcg tctatcagcc
    41041 caatactaac aggcagccga aggccaattt tacgcctact gcagagatga tggcgaagat
    41101 gggcaggttc aacgaggaac tcaaacaggc cggtgcgctg ctttcattgg atggactgca
    41161 gccgctcgcg accggcgccc gcctggcatt ctccaacggt aaggccagcg tgactgatgg
    41221 tcctgccgtg gacgccaagg aagtggtcgg aggcttttgg atgctgcagg ctacatcaaa
    41281 gcaacaggtc atcgattgga tgacacgctg cccggcgctg gatggcgacg tgatcgaaat
    41341 tcggcaggtc ttcgaattgt ccgattttca ggaggatgtc caggcaacgg cgaaaaaaca
    41401 tggttgagtg gcagcgggtt gcagaactgg acgcaagagt gcctatcctg ctgggagcct
    41461 gtgattcacg taaaaccgaa acatgaagga gagaacgata tgaccaagcc agcaaagaat
    41521 accatttgcc tgtggtacga ccgcgatgct gaggaggcgg cgcgttttta cgccaagacc
    41581 tttcccgact ccttcgtggg cgccgtccat agggcacccg gagactatcc ttccggcaag
    41641 aaaggcgatg tgctgacggt tgaatttacc gtgatgggca ttccctgcct tgggctcaat
    41701 ggcgggcccg ccttcaagca caacgaagca ttctcgtttc aggttgcgac caccgatcag
    41761 gccgaaacgg atcgatactg gcaggcgatc gtcaacaacg ggggcgaaga aagcgaatgc
    41821 ggctggtgca aagacaaatg gggcctgtcg tggcagatca cgccggtagt cttgacggac
    41881 gcggttacga attccgatcc cgccgtcgcc aagcgcgcat tcgatgccat gatgcaaatg
    41941 ggaaagatcg acgtcgcgac aatcgaggca gctgttcgag gttccaaaac ctagggtaga
    42001 gtctcttgtg gtgcgcccgg ctggaatcga accagcgacc ctcagcttag aagatccacc
    42061 ggacagcacg gggattaaga aagacggagt agtaaggata gccctaatgc cacatggata
    42121 aggggataat ggttgttgca gtgttacgga gtgggattat gtaagactgg caactgggag
    42181 caaaattagg agtcaaccgg gagtaaagcg gcaccctgtc gctgaggtat ttagctacaa
    42241 cccgctgaat tcaaaatggc ccgaaacgca tcaaccatcg tcggtgtggc tgcgacttag
    42301 gcggagggct tacttccgaa cagttttaac atcaggcctg ctctactccc tttcaaccct
    42361 gcatcctaag aggtacgaag acgcggatca ttctgcgtga gatcggcgtc acatcagccc
    42421 gggggagatc gagccatgta caaccttcaa cttcgctcgc cgccccatag cgaaacagac
    42481 agcactctcc aatgcgtccc atcgcattcg gaggccactt cgttttgaaa aaaaagacat
    42541 tgtacgtgca cctatccgag gcttgacggc gatagaagta ctccgtttcc caaacggcac
    42601 agatgatgca cgccatagag ttggcacttc ttcagcagtg ggtggttatt tccgtgcacg
    42661 gattgcatat gctcagggat gaaatttcga ggcatccgct catccctctc ggttatccac
    42721 gaaggatgcc ctccacatcc taagggagct gcggccatga aaatcaccct cagcatcatc
    42781 aaggcggaca tcgggtccat cggtggccac atttgtccct cgcagcaatt gctacaaacc
    42841 gtgaggagct atattgccca acacggttca ccgttgctca tcgaccatta tcttagtagt
    42901 acgggtgatg atatcgccat tctcatgagc cacacgcacg gccccgggca tgaagcgatt
    42961 cacaaactag cctgggacgc ctttgtcgct gggacggagg tggctaaaaa gcagggtcta
    43021 tacggtgccg gacaggattt gttgaaggac gccttttcag gcaatgtgca cggcatgggg
    43081 ccagcggtgg cggagatgga attcgacgaa cggccaaacg aacccttttt gtttttcgcg
    43141 gccgacaaga cagaccccgg ggcctttaat ctcccgctat atcttgcctt cgccgaccct
    43201 atgaacactc cgggtttgat gctggcaccc aacatggcgc gaggctttcg tttcgtcata
    43261 atggacgtta atcacacgga tggcgaccga atcatcgagc tttctgcccc gaaagatttg
    43321 tacgagattg cagcattgct gcgggacacc gagcgctacg tcgtggagtc aatatggtcc
    43381 ctctccagcg gcgaacaagc cgtggcggct tccacttctc ggctgcataa catcgctggc
    43441 aagtataccg gcaaggacga tccggtgatg ctcgtccggg tgcaaaagga tttccctgcc
    43501 accggtgagg tgttggcacc atatgccatt ggcccgtatg tagcaggggg gatgcggggt
    43561 tctcaccaaa tgcctttgat gccagtacct cttcagtctg gcatcagcta tttcgacggt
    43621 ccgccagtga ttacctgtgc ggcctttgcg atgcatgcgg gacggcttac cgagcctgtg
    43681 gatacgtttg tccacccatt ttgggaccgg gtccgcgaca acgtctcaga gaaagccatc
    43741 agcatgcgac gccaggggtt cttcggtgcg gccatgctac ctatggcaga attggaatat
    43801 accggtatta tggaaaaact gaagggtctt gacgcaagtt tcaaggtacg taaggcctaa
    43861 tccactcctt caatcaattt tttggatttc ctgatatcca tgagaagaga ggacagtcgg
    43921 ccgcgcaaga agcgctgtaa cacagcgacc ccgggtcggc ctctatgatc ctgcacaatg
    43981 ccaatcagcc acattatcgt cgcttaaggc agggattagg cttttatgca atctcccatc
    44041 gcaccatccg gaatgttgag tccatccgtc aaaacctttt ggatggcttg atatagcgct
    44101 tttgccgccg tctccttggg taataagata gccgcaccgg cggccctcat tgcgcgatca
    44161 gtctctggac tcgcatgcac cgacaaccca atcacgctcg tgtctgtcaa acgagacttg
    44221 atcaccgccg tcgcttcaat gccgttcatt ctaggcatat tcacatccat gatgatgagg
    44281 cgcggccgaa gtcgttccgc taactcaaca gcttcctggc catcggacgc ttcgcctacg
    44341 acatcaatgt ttgcaaaagt ggttaggaga ctccgcaaac cttgacgcat catgggatgg
    44401 tcatcgacca ataacgtgcg aatcggtgcg gtgacattta gagaaggagg agcagaatcg
    44461 gaatgagcct gaataaccgt cgcccctccc ttcacgggct gtaggccggt cgcactgctg
    44521 gtcaatggca gcaacagcct g
//
LOCUS       DAOQPD010000022        44409 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_329_length_44409_cov_24.017676, whole genome shotgun sequence.
ACCESSION   DAOQPD010000022 DAOQPD010000000
VERSION     DAOQPD010000022.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 44409)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 44409)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44409
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_329_length_44409_cov_24.017676"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..396
                     /locus_tag="PK063_07320"
     CDS             <1..396
                     /locus_tag="PK063_07320"
                     /inference="COORDINATES: protein motif:HMM:NF014696.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylserine decarboxylase"
                     /protein_id="HMZ96894.1"
                     /translation="KEKSIRVTVFLNVFDVHVNRMPCAGTVEGVNYQPGQFLVASKPE
                     ATLHNEQNAVMLKTESGAKVLCVQVAGLIARRIVCWVGQGDRVQRGERFGLIRFGSRM
                     DTFLPLGSKICVALGDRVKGGETIVGELR"
     gene            393..1196
                     /gene="pssA"
                     /locus_tag="PK063_07325"
     CDS             393..1196
                     /gene="pssA"
                     /locus_tag="PK063_07325"
                     /EC_number="2.7.8.8"
                     /inference="COORDINATES: protein motif:HMM:TIGR00473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003882 - CDP-diacylglycerol-serine
                     O-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--serine
                     O-phosphatidyltransferase"
                     /protein_id="HMZ96895.1"
                     /translation="MKSPTMRPPFAKGHRKRQAMYLIPNLCTTGNLFCGVFAILSVFN
                     GQHLVAAIAILVGMIFDMLDGKLARLTNSTGQFGIEYDSLSDVVSFGVAPGVLIYSYA
                     LSGQGMFGVAVMFAYVAMGAVRLARFNATVSTSDSKYFTGLAIPAAAGVIASLVIFDL
                     HITQLGSEVKPLLILVITFGLAFLMVSTIKYRSFKDMKFRRGDHFTYLVWGILALMLI
                     VAWPQAMLFVTFTGYAVSGPIARLWTMIAKSAGKPVAKTDGPVVETRES"
     misc_binding    1193..1437
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1608..3155
                     /locus_tag="PK063_07330"
     CDS             1608..3155
                     /locus_tag="PK063_07330"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - leucine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HMZ96896.1"
                     /translation="MTRMIRIFDTTLRDGEQSPGASMNVEEKLMIAKQLARLGVDIIE
                     AGFAYSSPGDFEAVRRIALEVEGPVVCSLARARPEDITRASEALKGAPRVRIHTFLST
                     SDIHLKHQFRMTREEAKKRAVEMVQLARTYVDDVEFSPMDASRSDPAYLCEVIEAVIA
                     AGAGTINIPDTVGYAVPQEFGGLIKRIKDTVPNSSQAIISVHCHNDLGMAVANSLAAV
                     VAGAGQVECTINGIGERAGNTSLEEIVMGLRTRRDWYGADTKVVTEEISKTSRLVSKI
                     TGMVIQPNKAIVGANAFAHTSGIHQDGLLKDKTTYEIMRPESVGLEQVKLVMGKLSGR
                     HAFRQRLEDLGYKLTEDEVNHAFERFKRLADQKKEIYEEDLEVIISEEVAKMSERVVL
                     KSFQVESGTNKTPKATVELEIDGKVVSHSGTGDGPVDAVYRTIAAMTQTKSKLLMFGV
                     NAITGGTDAQGEVSVRLEEDGRTVSGHGADTDIITAAARAYLNALNKLAYFAAKQAEG
                     IHKVSLI"
     gene            3258..3620
                     /locus_tag="PK063_07335"
     CDS             3258..3620
                     /locus_tag="PK063_07335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HMZ96897.1"
                     /translation="MFSTHLQQCPEFLAGDHTRLRELLHPGKAELELGYSLAHGLLDP
                     GKQSLWHRLKSSEVYYFIAGRGVMKVEEASMPVQAGSVIYVPPGAKQSLINTGTESIE
                     FLCLVDPAWKAEDEAVVE"
     gene            3639..4715
                     /gene="leuB"
                     /locus_tag="PK063_07340"
     CDS             3639..4715
                     /gene="leuB"
                     /locus_tag="PK063_07340"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HMZ96898.1"
                     /translation="MKAKIAVLAGDGVGREIVPEAVKVLTTVAERFGHTFEFQAADVG
                     GHAIDKVGVPLPAETLTLAKHSDAVLLGAVGGPKWEGLDYSIRPERALLGLREQLGLY
                     ANLRPAKLYPMLADASTLRREVIEGIDMLVIRELTGGIYFGKPKGVEKMPGGGERGFN
                     TEVYTTEEIRRIAVVAFEAARKRRKKVMSVDKANVLESSELWRRVVTEVQKDYADVTL
                     SHIYVDNCAMQLVRNPRQFDVLLCNNIFGDILSDEAAMLTGSIGMLPSASVGAKVSLF
                     EPIHGSAPDIAGKNIANPIATIASGAMMLSYAFQLDKEAAAIEQAIVKTLEQGFRTKD
                     IHAEGMRLVGTTEMGDAIVKNLPA"
     gene            4746..5933
                     /locus_tag="PK063_07345"
     CDS             4746..5933
                     /locus_tag="PK063_07345"
                     /inference="COORDINATES: protein motif:HMM:NF013595.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96899.1"
                     /translation="MIATLAGNGEPGYAGDGGPAAVASLNEPKGLCIDREGNVYIADS
                     ENHVVRRVDRKTGLITTVAGVGPGGTGGAMMAPEPVAMPPQEEEDPFADTSGDSTKAY
                     TQVTDLSGTVRYVTGGRLTIEQESGDGGPARRARLNFPSAVAVDRAGNLYIADTMNHR
                     VRKVDAKTGIITHVAGTGQARYSGDGGPAVQAAINEPTGLAVTDDALYIADQSNNRVR
                     RVDFATGVITTAAGDGSAAYSGDQVPAVQASLAGPSGVAVGNDGLLYVADTFNSRIRS
                     VDPATGQITTAAGDGGTYRYQGPEEPASPSLSRPAGLAVDYDGNVYITDSDSHLIRVW
                     NGRTKTITRVSGTGVAQFGGDGGNALAGSLSYPFGVAVDAAGTVYVADTFNHRIRVLT
                     ATA"
     gene            5944..6963
                     /locus_tag="PK063_07350"
     CDS             5944..6963
                     /locus_tag="PK063_07350"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HMZ96900.1"
                     /translation="MLKKKQAYTVAVLGATGAVGKESLEILEERNFPIETLRLFSSKR
                     SAGEVLTCQGKEYKVEELTEASSFAGVDIAFISATDAISRDYGARLGAAGIVVIDDSA
                     VFRMDPDVPLVVPEVNAAALQSMKRGIVAIPNCTTTPLVMALKPLRDVAGIKRVVVTT
                     FQSVSGTGSAAMDELVDQTKALISFQDVKVQVYPYQIAFNLLPQVGSFGDGGDCSEEV
                     KIVQETRKILDMPTLRVTATTVRVPVLRCHSEAINVELERPMKANDARAAIAEMPGVI
                     VYDDPVKKLYPMPFDVSGKDEVYVGRVRVDESITNGLNLWVVSDNLRKGAALNAVQIA
                     ECLIQ"
     gene            6967..7221
                     /locus_tag="PK063_07355"
     CDS             6967..7221
                     /locus_tag="PK063_07355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2905 domain-containing protein"
                     /protein_id="HMZ96901.1"
                     /translation="MGAWSGIGRLFIVAGLALAGVGILLTLLERWSGAGAAFGWIGRL
                     PGDLSITRERFSLYVPITTSLVLSILLSVVLYILSWIFRR"
     gene            7260..8411
                     /locus_tag="PK063_07360"
     CDS             7260..8411
                     /locus_tag="PK063_07360"
                     /inference="COORDINATES: protein motif:HMM:TIGR02669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIID/LytB domain-containing protein"
                     /protein_id="HMZ96902.1"
                     /translation="MALAGIVFAQSASAESIRVLLVQEAPFVDVRSDGPLALVMETGD
                     TKTLHGPIHLTARADGLHVDGRRILGGQVLIRSLRHNLTLVVGKEGGSAGTPLPISGT
                     VRVSRKGHAVAVVNQVDLEEYVKGVVPSEVSSAWHPEMLKVQAVAARTYALYNKMLSA
                     ARDYDVMATIQDQVYRGRTGVDHRVEEAVESTRGIVVTHQQAPIYAAFSSTAAGPTED
                     AVNVWANKDLPYLKGVECPFDLESPYYQWKASVKIEQLEKNLRHQGFAVGTIATITPI
                     AFSRAGRVARLRILHSGGETLLRGEDLRKAAGYTVIPSTQFEVESIGAEVVFAGYGAG
                     HAVGLCQWGAKELAELGYSYNSILQYYYPGTELRNSALSQLMMPVIPTP"
     gene            8411..9451
                     /gene="queA"
                     /locus_tag="PK063_07365"
     CDS             8411..9451
                     /gene="queA"
                     /locus_tag="PK063_07365"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: protein motif:HMM:NF001140.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HMZ96903.1"
                     /translation="MLLSEFDFPFDPALVADRPVLPRHDARLLVMDRSSHARMHRRVA
                     DLPSLLQPGDLIVVNNTKVMPARVPAQTRSTGKILDLLFVQDLGQGLWEVLIKGRFKP
                     GAFIDFPGGGCGEIVERSQARTTVKVTGVTSVYDLMHNTGTMPLPPYIKREPSQDDQR
                     WYQTMFAQQEGAIAAPTAGLHFTPELVETLTGKGMELAEVTLHVGPGTFRSVKSDRIE
                     EHRMLAEQVEVTARTVEQIRLAQKRGNRVVAVGTTVVRALETAGRGGRGIQPFQGPAE
                     LFITPGFEFQVIDALVTNFHLPRTTLLMLVSAFVGLEPLRAAYEEAVSERYRFYSYGD
                     AMLIAGGLSAAT"
     gene            complement(9444..10142)
                     /locus_tag="PK063_07370"
     CDS             complement(9444..10142)
                     /locus_tag="PK063_07370"
                     /inference="COORDINATES: protein motif:HMM:NF025010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SurA N-terminal domain-containing protein"
                     /protein_id="HMZ96904.1"
                     /translation="MIKLLREAAHDYPWFLKSIMGTLALAFVITMGWWGFGDQSGNVV
                     ASVGDQVVPLDEYRRAYENTYRFYKDKGQNDIKDEFLKQFVLEQLIDNRMWLHVAKEM
                     GLSVSDEDLRKAIMQRTEFQKNGNFDPESYRRLLAANRLTPASFEAMEAKDILTNKAR
                     LVIMDAVALTPSEYAEAQTLVSREGESDPTKAAIAKERIFQNLLFQKQQRALMAYSES
                     MKSKVPVKIHKELM"
     gene            10146..10763
                     /locus_tag="PK063_07375"
     CDS             10146..10763
                     /locus_tag="PK063_07375"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96905.1"
                     /translation="MRLFSAGFRGFYSGDDSKGKRKKCAESGCEKIATLFVQVKEICY
                     SVEELGRFPVAEEAIGRSPVELGVYPKAQVLNRFIAKMIDLLIVAAVSKLVPPIGVLA
                     GLAYILLGDGFGGGRSVGKRLIGLQTIVPRTRDPAGFRESIIRNLPCGLAQLAFEIPY
                     VGWIGWGAVLSLEGLLVIGNEQGRRLGDEIAKTQVLESGQLDVSD"
     gene            10812..11861
                     /locus_tag="PK063_07380"
     CDS             10812..11861
                     /locus_tag="PK063_07380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000902 - cell morphogenesis [Evidence
                     IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HMZ96906.1"
                     /translation="MAFMSDMFGWFSNDLAIDLGTATTLVYVQGKGIVLNEPSVVAVE
                     KKTERVMAVGADAKRMLGRTPGNIIAVRPMKEGVIADFEKAEAMLSHFIQKAHNRTAF
                     VRPRIIIGVPSRITQVEQRAVRDSAELAGAREVYLIEEPVAAAIGAGLPITEPSGNMV
                     VDIGGGTTDIAVISLGGIVYSESVKVAGDRMDDAIMNYIKKKYNLLIGEHMAERIKFE
                     IGSAYPFEERKTMMIKGRDLISGIPRTLVVDDAEVREALQEPIGTIVNAIKVALENTP
                     PELAGDIIDRGIVLTGGGSLLKGMDTRFREETNLPIITVDDPLTSVVLGVGKILDELD
                     LLRKVSVMSQCSTSR"
     gene            11880..12761
                     /gene="mreC"
                     /locus_tag="PK063_07385"
     CDS             11880..12761
                     /gene="mreC"
                     /locus_tag="PK063_07385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HMZ96907.1"
                     /translation="MAISRSTYGTRRLAIVLFACLLVALFLLPSQSQRLLQYVGGPLG
                     QVLSLPLAAFSSVDHGIADMWNGYVALQTVREENRQLHRDIELLKGQNNQLRESMTAV
                     QRYEALLNFKQQSPSQTLAAQVIGRDATNWYRGMILNKGENDGVRTEMGVITPAGVVG
                     RVVKTNATSSVVLLVTDPNNAIAGVVQRTRDEGIVEGTSHGRARLKYIPLLSNVQAGD
                     RVVTSGLTGAFPRGLAIGSLIQVEKSEGDLFQSAEIEPEVDLSKLDEVLIITAPYEDA
                     DAAQKLLQAIHGDRKKP"
     gene            12758..13258
                     /locus_tag="PK063_07390"
     CDS             12758..13258
                     /locus_tag="PK063_07390"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96908.1"
                     /translation="MKFLLYLLLALVVVPLQTTLLHYASVFGVRPDLGLIAACLVGFL
                     GGELDGLILGLILGCFQDMLSAGDLWINVVTKGGSGFLAGLAGRHMAHITPAVMTAGL
                     AIISCLSSAVFLYSMNPAGLDEVWLGVRSTVLVQAGLDAALGAGLYLLFRQRWSDDRM
                     VTEGAL"
     gene            13300..15183
                     /gene="mrdA"
                     /locus_tag="PK063_07395"
     CDS             13300..15183
                     /gene="mrdA"
                     /locus_tag="PK063_07395"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: protein motif:HMM:TIGR03423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HMZ96909.1"
                     /translation="MATVGFNDSDLLDLQRRLVILRVGLLLVVALLALRLWHLQIREG
                     PYYRDLSENNRTRSVVLEPARGLIFDRNGVLLANNVPSFALYVTLEDVKDRQALVGQL
                     ASLLALDPEVIQKKLSTGKGGKLQPRKVKDRLTLREATLIESHRLDLPGVMIQVESQR
                     NYPAGAVAAHLLGYVGEVSADQLEKPDFADLHQGSIVGQYGVEKWFDRQVRGRAGQKS
                     VEVDALGHEKRAIVSDKPLAGDDLYLTIDAKLQKVAEDLLGDESGAIVALDPTNGDIL
                     AMASRPGFDPNVLSKELTNKQWVEIVQNERRPLNNRATQGQYPPGSTFKVVMAAAALE
                     SNTVTPSTMVRCNGGYQFGNRLFHDWKQGGHGSVDMNEALIHSCDVYFYTVGQRMGID
                     TIAEYAKQFGLGQETGVELPSERVGIVPSTAWKQKARNQPWYPGETISAAIGQGYVTV
                     TPLQMASVIGTVANDGVSIKPRLVQAVMNRTTGERAEFPPTVRGKVAVKPATLALIKS
                     ALADVVTKGTATRAKSPLVTIGGKTGTAQTAALRTGPEKDIPKKFRDHAWFVAFAPVE
                     APRIAVAVLAEHMGHGGSAAAPLAKDVIEAYVKAYPQVLQGAPASGRAKSPAVPVDTR
                     PKT"
     gene            15183..16301
                     /gene="rodA"
                     /locus_tag="PK063_07400"
     CDS             15183..16301
                     /gene="rodA"
                     /locus_tag="PK063_07400"
                     /inference="COORDINATES: protein motif:HMM:TIGR02210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HMZ96910.1"
                     /translation="MIDRVIDSRGLDSFDLRFMGLIAVILSVGVLSIYSVTHSQDTAF
                     PFYLKQLVWILLGTVAFLVMYLSDYHKIARLAYPTYAVILIMLAVVLFMGKSSRGAQR
                     WIPIGPFAFQPSEFAKLVLVLVLANYYSRASRVGWLHRVVLPGLIVLPGLLLILKQPD
                     LGSGLSFLAVYAAMLLMVGVRSKALGIILLLSVMLFPFVWEVVWASLHDYQRERVMAF
                     VDPDYDPGGKGYHALQSRIAIGSGELSGKGLYGGTQSQLKFLPEGHTDFVFAVYAEEW
                     GFVGVLVLLALFIALIWVSLEIAARAKDTLGALLAAGIVAMLCFCVVVNIGMTAGMFP
                     IVGIPLPLVSYGGSATIMTMASLGLLLNVKRRRLTLFY"
     gene            16444..17955
                     /locus_tag="PK063_07405"
     CDS             16444..17955
                     /locus_tag="PK063_07405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - ribonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HMZ96911.1"
                     /translation="MGVEIAISIAREETRVAVLDNGVVTDLYGDRAKDQDYVGNIYKG
                     RVAKVLPGMQAAFIDIGLEKAAFMHVSDLSIDVEPGDTLVEGDDEDNKDSEVPKPKRQ
                     SSKPIEELLSEGQELMVQISKGPIGTKGSRVTTYVSLPGRYLVFMPTVEHIGVSRRIP
                     RDEERARLKEIMKRARRPGFGYIVRTVSEGVKEEELRSDVEFLHVLWQDVLTKRDQQP
                     APSLLHSDLSLSFRVVRDLFGRRVDRLLIDSREEYNAIKGFVQRFSPEQTSRIHFYDK
                     EESLFDYLGVEQEIARAMSRKVWLKSGGYLVIDHTEAMTVIDVNTGRFVGKRDQEETI
                     LRNNLEAAREIAYQVKLRGIGGIIIVDFIDMEREKNRDKVYHALVDAMSSDKARTRIS
                     RVSDLGLIEISRERVREDLLRSLSEPCHYCDGRGYTKSPMSVAYEIFREVRRLGHEIE
                     QQRVVVGAHPAVALLLQEQEQPGVEELERRYSAKILVTPDDRLHLEQFDLVVM"
     gene            18065..19186
                     /gene="dprA"
                     /locus_tag="PK063_07410"
     CDS             18065..19186
                     /gene="dprA"
                     /locus_tag="PK063_07410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HMZ96912.1"
                     /translation="MVNSLSLRPWLMLRAIPGVGDAILLKLVQAMGSPDAVLSATQAS
                     LEDVGCRVPLIDAIRRGPDAQAVKQLDRELAAVQHRQITVLTYLDPQYPAPLKTIPDP
                     PPLLYVQGTLLESDRQAVAIVGTRKVSSAGRVLAEELACELAEMGFTIVSGLARGVDA
                     AAHRGALAGKGRTLAVMGCGLDRTYPADHAALRQEIERHGAVLSELPLGSAPHSYHFP
                     RRNRIISGLSLGVVVTEAAVESGSLITARLAGEQGREVFAVPGFVKAENSRGPNSLLK
                     DGARLVESAQDILDELLPQLDAAFRERLGDRARGARPAMQLGPEEAMVYDAVSVLPQS
                     VDDVIRRSGLAAAQVTAVLLSLELKNCVRQLPGNEYVRL"
     gene            19282..21621
                     /gene="topA"
                     /locus_tag="PK063_07415"
     CDS             19282..21621
                     /gene="topA"
                     /locus_tag="PK063_07415"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HMZ96913.1"
                     /translation="MAKSLIIVESPTKARTITKYLGRGYSVMASVGHVKDLPTSKLGV
                     DLEHDFEPQYVTIKGKSKVLADIKKKAQQVDTVFLAPDPDREGEAIAWHIAQELHGKG
                     KKKDGKVYRVLFNEITESAIKRALKSPGEIDMKLVQAQQARRVLDRIVGYQGSQLLWK
                     KVRRGLSMGRVQSVAVRLICDREQEREKFRAEEYWSIVALLRGDNPPAFEAKLHSING
                     QDADIGTSAQAEQILNAVQGKAFVVQSIERKEKKRNPVAPFITSRLQQEAARKLHFTP
                     KKTMTLAQQLYEGVEIGAEGPMGLITYMRTDSPRISQEATEDARLVIRERFGEEYLPA
                     TPNVYKTQKAAQEAHEAIRPTMAARDPESIRQFLEQDQYNLYKLIWNRFIASQMVPAI
                     LDVTRVDSSLIGTPERYVFRTTGTVVKFPGHTAVYLEGTDKELPSQKPKSEQESEDES
                     DRQLPVLREGESLHLVTQEAQTLPGLISKQHFTQPPPRYNEALLIRELEEKGIGRPST
                     YAAIISTIQDRKYVEKVEGRFLPTETGRTVNDFLLKGFPDLLDTEFTSHMEEQLDEVE
                     EGTKPWVSAVREFYAPFVREMELAQSIPGPKDIVEPPTNLPCEKCGRMLEIKWGRNGK
                     FLACPGYKEDPPCKNTQNFEKLPDGTIKIVPKLEETTDEKCEKCSSPMVVKSGRFGKF
                     LACSAYPECKTTKAIALGVKCPQPGCGGDLVQKRTKKGRNFYSCSRYPECEFALWDRP
                     INKPCPKCQAPFLIEKVSKQAGRSVQCRNEEECGYREAG"
     gene            21929..22405
                     /gene="bfr"
                     /locus_tag="PK063_07420"
     CDS             21929..22405
                     /gene="bfr"
                     /locus_tag="PK063_07420"
                     /EC_number="1.16.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004322 - ferroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA];
                     GO_process: GO:0006880 - intracellular sequestering of
                     iron ion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin"
                     /protein_id="HMZ96914.1"
                     /translation="MKAKQGVIELLNKVLTADLTAINQYFVHAKMCANWGYERLHHKV
                     RERSIDEMKDADELISHILYLEGVPNVQRMNTVHIGETVPEQLKLDLKAEQEMLALLS
                     EGVVHCTKVADFTTRHMFEDMAKDVDEHIDWIETQMETIKQIGLENYLAEQIKKDS"
     gene            22440..22919
                     /gene="bfr"
                     /locus_tag="PK063_07425"
     CDS             22440..22919
                     /gene="bfr"
                     /locus_tag="PK063_07425"
                     /EC_number="1.16.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004322 - ferroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA];
                     GO_process: GO:0006880 - intracellular sequestering of
                     iron ion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin"
                     /protein_id="HMZ96915.1"
                     /translation="MKAKEGVLDILNKVLVSELTAVHQYLLHAALCKHWGYARLHEHF
                     SHLAQEEVSHSSGLIDHILYLGGSPEMGRLDAVAAGKKVSELFSADLAFEREDADALR
                     QGIAHCAKVGDFTTRHRLEDMIIDTEEHIDWFETQLRTIEQVGEDRYLAEQLTADKS"
     gene            complement(23027..23587)
                     /locus_tag="PK063_07430"
     CDS             complement(23027..23587)
                     /locus_tag="PK063_07430"
                     /inference="COORDINATES: protein motif:HMM:NF024242.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HMZ96916.1"
                     /translation="MMSGKSSTSNISFDRLHSFSSELRVQSPQWADRLEQVRTEQDLG
                     DLICDLFNLSHAINPETQPPPIPHTQPSRIAAFVNENLHRGVTLKVLANFLGYSEKYC
                     SDLFCRIMGEPFSKYLRRQRVERARALLITTRQTLTEIASALGFSDQFAFSHFFKRAT
                     GQSPMAIRLTIARQQRQTIQGLQQTS"
     gene            complement(23645..24400)
                     /locus_tag="PK063_07435"
     CDS             complement(23645..24400)
                     /locus_tag="PK063_07435"
                     /inference="COORDINATES: protein motif:HMM:NF014069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing phosphohydrolase"
                     /protein_id="HMZ96917.1"
                     /translation="MHRSTRPIPTTSQLIQDLATQLSALNTLQLSPESLEAVRVIQLE
                     RLARRIETVIPGHFGHGERTAHYALLLADRLRLTKHQRLDLHYAALLHDVGLLMMPGH
                     LLGAPAPHTLNDYALIQSHPREGAALLTPYTFLQVAARLIAHHHERWDGAGYPYGLRG
                     EYIPASARILAIADVFDSITSRTNSWDSALRTLHASAGSQFDPAFCVTFIELLRNHDH
                     YRAYQSSDLSSDAMHSQSSPEHVPEAYMTGSGI"
     gene            complement(24506..25024)
                     /locus_tag="PK063_07440"
     CDS             complement(24506..25024)
                     /locus_tag="PK063_07440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96918.1"
                     /translation="MRNFNTRFRLRDSDRHIRLVYTFFLLLMLAGFTFSFFWAHSMTG
                     LSPQGIADHYRGSNATFGEPMSFRELAEITHFHLFTMPVVFMILVHVLYLTNASNRLK
                     IVTTWLSFGGVILDLLSPWLISYVSPVFVLTMLTGDTFMTAGFFIMFVIPLHEMWILK
                     QPLMAGKRGEHA"
     gene            complement(25037..25714)
                     /locus_tag="PK063_07445"
     CDS             complement(25037..25714)
                     /locus_tag="PK063_07445"
                     /inference="COORDINATES: protein motif:HMM:NF016121.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HMZ96919.1"
                     /translation="MMPLLLLLTLTGAFALAPLNAQAERVWDNELKRYLTEQEMSLAE
                     VFLTEEEAVKLMFPKSERVRRELLNLPQDKKALIESRIGWKFPEESFEVYIGETGTHI
                     DGYALVQNTIGKHKPMTYMVGVDAHGLVSNVELLTFREARGSEVRTKRFNVQYEGKSV
                     LDPVRINKDIINISGATMSVRSMTAGIKRVLVLVDEFYLKPQGRGSDTVTAQKTEKGF
                     FKSIFGN"
     gene            complement(25711..26211)
                     /gene="bamC"
                     /locus_tag="PK063_07450"
     CDS             complement(25711..26211)
                     /gene="bamC"
                     /locus_tag="PK063_07450"
                     /inference="COORDINATES: protein motif:HMM:NF018509.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamC"
                     /protein_id="HMZ96920.1"
                     /translation="MGRAAGFTRGRISVQRAHIFIAAAAFLTIGCASLSGSHEQSYSC
                     SQDVVWDAAMDTMKSYSITSQDKAKGVIETGWLEMDGKERSYGIFGRTGFGNRERARM
                     SLALKTSNGAVSVSLLETRQRWHSRGGVTSQATKWWPVEPSEEATAEVTTRLNEKLKQ
                     QGCTPL"
     gene            complement(26236..27714)
                     /locus_tag="PK063_07455"
     CDS             complement(26236..27714)
                     /locus_tag="PK063_07455"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HMZ96921.1"
                     /translation="MKIRAILGALVLASLPAMPALADNMTPEEIKKLVDEAVEKRLQE
                     HERREGAGDHRETVGAPGNEPGIGSLPEVGKERRTENQAALSFGSTGSGRLVYAKPFV
                     AAPKAIVGGYMDIQYRSHRNGVLESGMGSGTTNGFDQQRFVPFIYADITEHVKFAAEI
                     EIEHGIREDATQGAEIGLEFAHIDYLVKEPFNLRAGILLVPIGKFNLLHDSPLNDLTD
                     RPLVSRLVIPSTMAETGAGFYGTLYPGRTSKLDYEFYVTTGPCGYNGDGSPRIREEDG
                     TRRSRQRKCPSEDGLDINNGKAVSGRVAFSPMLGVEVAGSSYFGNASPLSYNPLSITA
                     IDWTFQRGPFELLGEAAWAYARGNSRAVQGATFATPGSLLSGLNTLNSFAAPPQRMQG
                     FYVQANYHFMPAFLTALSPKRFGEGSTFTAVFRYDRVNLNMDNRGENSGELEQFSFGL
                     NYRPIEDAVFKASYQYMPKSFNPNTGQRIHDSAFVISAATYF"
     gene            28290..29390
                     /locus_tag="PK063_07460"
     CDS             28290..29390
                     /locus_tag="PK063_07460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HMZ96922.1"
                     /translation="MKLSINSHPLRAFLFMFVNDAVLRRGFALAIRGSLGLLLLLGLG
                     CAGGNLGSSPILVKRTQMHMGTWVSITAVAPDREAAQYAASAGFQEIHRLEELLSTWI
                     KDSELSRVNGAAGKEAVSVSPDTMKVLQASVAMARLTGGGFNILVGPAVEAWSVLDRQ
                     QIPSESELENIRPLTNLNALQLSQAQGTVYLAKPGMRVDVGGIGKGFAADMAVEAMQK
                     AGATAGVVALSGDIRTFGQMPDGTTFPFGIRHPRREGTVLAFVDLQNEAISTAGDYER
                     YFERDGVRYHHVLDPVTLQPARDCQSVTIVAKDGLTADGLDTGIFVMGPERGLALVES
                     LPGVGAVIVDRDGKVWVSSSLKGRVRIKDGVD"
     gene            complement(29471..29731)
                     /locus_tag="PK063_07465"
     CDS             complement(29471..29731)
                     /locus_tag="PK063_07465"
                     /inference="COORDINATES: protein motif:HMM:NF015506.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0031992 - energy transducer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy transducer TonB"
                     /protein_id="HMZ96923.1"
                     /translation="MPRIEALKEYPVDARLKHVEGRVVVRIVIQEDGQIVSAAVAKSS
                     GHDTLDQAALETVRKISPIALTQPLEQSPVTLHVPIRYQLGP"
     gene            complement(30418..30792)
                     /locus_tag="PK063_07470"
     CDS             complement(30418..30792)
                     /locus_tag="PK063_07470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biopolymer transporter ExbD"
                     /protein_id="HMZ96924.1"
                     /translation="MEREVNQINVIPLVDVMLVLLVIVLTTATFISTGQIPVNLAKAK
                     EAGDHKDVPVVVTLTANGDLFLNDRPVPADGLKSVMLTHPRESLVVVRADKVTLLERF
                     VSVVDEIRGLGFQSVSLEVVRL"
     gene            complement(30776..31207)
                     /gene="exbB"
                     /locus_tag="PK063_07475"
     CDS             complement(30776..31207)
                     /gene="exbB"
                     /locus_tag="PK063_07475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0015291 - secondary active transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-system energizer ExbB"
                     /protein_id="HMZ96925.1"
                     /translation="MDVLKNAVEYGIIGLLIALSVWSVAVAVERWLYYRRVNLAQFTD
                     VQTFEMALTKRLVIIGTVAANAPYIGLLGTVLGIMMTFHTMGTSGTMAVNTIMIGLSL
                     ALKATAVGLLVAIPCVVMNNILRRRVAELLTTYKVQHGTRG"
     gene            complement(31307..32446)
                     /locus_tag="PK063_07480"
     CDS             complement(31307..32446)
                     /locus_tag="PK063_07480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ96926.1"
                     /translation="MNESITGRQQPASEGIIPNTLDTTVERSAVLELRDVSCAYEPTR
                     PAIEGITFTVHQGEILCLLGPSGCGKTTILRAIAGFERVTRGTIALSGQRVSSPDTMI
                     PTEQRHIGMVFQEYALFPHLRVEKNIAFGLRHLPRTEQQAIVDDLLTLTGLRGLEHRY
                     PHELSGGQQQRVALARALALRPVLLLLDEPFSNLDPDMASRMRQDLHALLRQTKTTAI
                     LVTHDHDEAFSMADRVAVLNKGRLEQFDTPEAIYHLPTTPFVADFVGQADFIAGVVTH
                     HLVTTELGDFPNTQHLATGTHVVVMIRPDDIHIVPTKGADARILARQFKGSENVYTIQ
                     LPSGQIVHSSESSLSIYQVGTAIALRVVATHTVLFPQPPGSPPVA"
     gene            complement(32452..34056)
                     /locus_tag="PK063_07485"
     CDS             complement(32452..34056)
                     /locus_tag="PK063_07485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HMZ96927.1"
                     /translation="MLTATRVRAPSSLQWISLFTAAFLVLPTAYIVYVAMTAAPAVWA
                     RLWSTRIPELLGNTLSLALGVALITLVLGVSLAWITVRYDFPGRRIWEWALALPLAMP
                     TYVLAYVYAHLLGMGGPTEQWWQLLFGHEARLPSPQSFPGVTMIMALDTFPFVYLLVR
                     SAIQNLNVSFEEVARACGVSPWATLRRVTLPLIRPAIAAGLALVILYVISDFGAVSLL
                     RYQTLTYAVYQQMTSRYDHTAASILSLLLVVMAIIFLVTERWFRQRSRFYQTSGRYRR
                     STRQHAGPLGTALITSYVVLVFGAAFGIPAAMLIQWSVEAISQGALDTRFLGFIWNSS
                     FLAALAACGAVIIGLPLAYLASRRPSRLNIACLQAAYAGYALPGPVAALAVLVLFTHF
                     APALYGTVVVLIIAYILHFLPVGLQSMEPALQQVTPNVEEVARTLGCTTHQSLWRVTL
                     PLVRNGFVAAWVLMFLQTMKELPATLLLRPVGFDTLAIRVWLEASEEYYQLAAPAALL
                     IVILSLPALMLLVSKDWRGEAQKGVT"
     gene            complement(34072..35103)
                     /locus_tag="PK063_07490"
     CDS             complement(34072..35103)
                     /locus_tag="PK063_07490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HMZ96928.1"
                     /translation="MASFPRTVFALTLLISALILQEWPAKTADAADKLVVYSGRAERL
                     IKPVLDEFQTKSGIQIELLSSGTTELVNRLQAEGDHTPADVFLTNDAGSLEHARELKL
                     LRPMNMREVERAIPSQFRASDNSWIGLSGRFWVVVYNTTLVKPEQIKSLLDLAQPQWK
                     DKIAIPNSGSEYLQAGVSVIKTTFGDERTKQFLQGLKTNAGSQVYQKSSQIVEAVAKG
                     QVAAGIVNHYYIYRHLAAQPTAPIAAIMTDQQEGGMGAIMNVTGIGVTRASKHVDSAK
                     LLIEFLVAQAGQKLFADLDKEYPLHPDVKADPALVDRHSFRAALVPLARLAELRESTL
                     TLIEQVGLR"
     gene            complement(35195..35626)
                     /locus_tag="PK063_07495"
     CDS             complement(35195..35626)
                     /locus_tag="PK063_07495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HMZ96929.1"
                     /translation="MSKNLKEMDVLRQHLAKHQLKLTRQRELILTAFLRQEHVTAETM
                     YHQLAKKDPHLGLATIYRTLNLFCEAGIAQARHFGTQTQYDNISHKGHHDHLICTGCG
                     TIVEFENCEIERLQEEVATKNGFVIQTHRLELYGLCARCRH"
     gene            35778..36341
                     /locus_tag="PK063_07500"
     CDS             35778..36341
                     /locus_tag="PK063_07500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96930.1"
                     /translation="MRKSHEMTVDRALLLYVLSLAEPYGLLSDVKLQQLCFLCELQMF
                     GKGLKGFHFEFVRFAYGAFSRDLDNDLTSLRRKERVENFSPSDQVRDETLPLLLKGID
                     GNETNEKVRDLMQAVIATYGPQDVTAIMQSVESVELSTPQQPDFKIPIRDIVFHTTLL
                     VPSRIEAPAEFLLPANHLAKLNVSMGY"
     gene            complement(36475..36861)
                     /locus_tag="PK063_07505"
     CDS             complement(36475..36861)
                     /locus_tag="PK063_07505"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96931.1"
                     /translation="MANILIINADSNLKRLIKLALPGMEHFVQYSATLHNASAQPPAS
                     KLDLVVARLVADDDQGPEDLVDLRKAFPSSRIVVTAALHEPALEGEKFQRVVRELQIE
                     YCLLEPIETGAMLHTIQSALTLPRRH"
     gene            complement(36996..37682)
                     /locus_tag="PK063_07510"
     CDS             complement(36996..37682)
                     /locus_tag="PK063_07510"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ96932.1"
                     /translation="MNAFDTLPAVKTELNILLADDHALLRRGLKEFLQDFLTEDGLTP
                     HITETDSAHSAIDQIRTGAWDLVILDLNLPDMPGLEVLRIVKSLQPSLPILIVSIYAE
                     QHYAARAIRAGALGYLTKDTGPQQLRAAVSRILQGGNYFPPPQSEQVSDTMLDRNTPC
                     AHDLPAVLSDREIEVLQWIAQGRRLTEIAEHLNLSIKTVSTYRARLLTKLGMKTTAEL
                     IRYALDQQLV"
     gene            complement(38152..39672)
                     /locus_tag="PK063_07515"
     CDS             complement(38152..39672)
                     /locus_tag="PK063_07515"
                     /EC_number="3.4.17.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HMZ96933.1"
                     /translation="MKTLKTLEPLTNRLLEIRRIQSAASVLSWDQETYMPAGGGAARA
                     EQIATLEGLAHERLVSPHIESLLNEWIDPSTGQAAEHWDEPSRSLLRETWRDFSRARK
                     LPSDFVIRLSRECSLAQQAWVTARAESQFSKFLPSLRTILDLKCEETQYLGYRDSPYD
                     ALLDTYEPGATVGQLTPLFAQLRARLVPLLKRVQASKVRIDDTCLHHSFDHTKQIEFG
                     RLVLVAMGYDFERGRLDLSAHPFTTSFHPTDVRVTTRVFEKDLPSCLFSCIHEGGHGL
                     YDQGLDPRYYGSPLGESVSLGFHESQSRLWENCVGRSRAFWQCFYPILQHTFPQQLAG
                     VPLDQFYAAINRVTPSLIRVEADELTYNLHIMLRVEIEQALIERRAHPEDLPSLWNDR
                     MEAYLGITPAQDADGVLQDVHWSMGAFGYFPTYTLGNLYSVQFFEQAKLELPQLEEQI
                     AAGQLVPLRHWLEQKIHRWGRMFTPDHLARRVTGNGVTPEPFLRYLEAKYGALYRL"
     gene            39757..40407
                     /locus_tag="PK063_07520"
     CDS             39757..40407
                     /locus_tag="PK063_07520"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HMZ96934.1"
                     /translation="MADLVSPNIDAYAAACSLPETPVRRALREETERTMEYARMLVGP
                     LEGAFLHVMTRLVRAERVLEIGMFTGYSALCFAEALPDQGRVITCEVDEDSAAVARRF
                     FAQSPHGRRIEIRMGPALETMAELTGPFDLIFIDADKLNYVNYYRRAMELLSPRGVIL
                     VDNVLWGGDVLTDPPPDDRTAAIQDLNRIVAADPRVTAVLATIRDGIWVITHKSSH"
     gene            40466..41377
                     /locus_tag="PK063_07525"
     CDS             40466..41377
                     /locus_tag="PK063_07525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HMZ96935.1"
                     /translation="MEKPSASAAYAALTISALVWGGSIVGQKLALGAFSAVETSLIRG
                     IGALAILIPLWWWTEGNRTTLTARDLKVLSLLGLFVFGNHLLTLFGLRYIGASTAGVL
                     IGASPAITALLSSLLVRDIPFNQVAGGCAVSFAGVALVSGVGGDAPIGDHPWLGGTLV
                     LLGLVSWALYSIGGRQVMNRLSPLTVNWTTLLLSLLLQIPLLSTDQKMLVTGTSAVPV
                     SGWLAVGYLIVFATALGQQAWLYGVQGVGPSRAGVFVNLIPVSALLLSAVILGEAIGA
                     REIAGIVLILMGVWLVGRQTEPSKRRG"
     gene            41573..43093
                     /locus_tag="PK063_07530"
     CDS             41573..43093
                     /locus_tag="PK063_07530"
                     /inference="COORDINATES: protein motif:HMM:NF013179.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ96936.1"
                     /translation="MIEHHDTGLSRVLVISTRPDGIITSFNSAAERLLGVGADAVVGK
                     VTPAAFHDPDELRRRREALAAGLGKPIQDSFGVLVARVAIGRMTEDEWTYLDRSGYRF
                     PVFLSVSAIPDEAGHVLGYCFVAKDRRGQLQAEALLRRQAKLLDLANDAILVRDLQAD
                     TITYWNEGAVRLYGWTAEEALGAYIHDFLSTTFPLPLEEIKQQFLEQGLWRGELVHKT
                     RAGREITVSSRWTLLRDAAGMPSGSLELNTDITEQKRAQKALKDAHEELELRVMERTT
                     DLRDANERLRILSRRLMEIQELERRAIARDLHDEIGQALTAIKLNLRELRTHPNCEPV
                     EDQIADSLEILAQVLQRVRSLALDLRPSLLDELGLVPALRWYVGRQAERAGWQLTFSA
                     DGLTSRPPAEIEIACFRLAQEALTNVVRHSQAKKVEVLLERSSQALTMVIRDNGIGFD
                     RDEVRSGASVGLSGMEERVQLVGGAFSIESTPAVGTEIRAYFPHGVATKGTEDSLV"
     gene            43090..43743
                     /locus_tag="PK063_07535"
     CDS             43090..43743
                     /locus_tag="PK063_07535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ96937.1"
                     /translation="MNKIRVLLAEDHTLVRAGFRALLEKLEGIQVIGEVSDGRDALRV
                     AKELDPEVVLMDIAMSGMNGLEATSRMRQECPRTKVLMLTMYTNEEYLKEALRAGASG
                     YLLKDADRPELELAIKTVCRGETYLTPAMAKFTLDAYCRQDDVPMSPLSKLTGRQREI
                     LQLIAEGCSTKQIAHRLDLSVKTVETHRAQLMERLEIHDVPGLVRLAIRTGLVRSDT"
     gene            43952..>44409
                     /locus_tag="PK063_07540"
     CDS             43952..>44409
                     /locus_tag="PK063_07540"
                     /inference="COORDINATES: protein motif:HMM:NF013567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HMZ96938.1"
                     /translation="MKKLRVAVLGTGAFAEACHVPGLQSHPGAEVVVLCGRNSARTRA
                     MADRLGVPEISLDYEQVCARNDIDAVTIATPNVAHALQAKAAFSAGKHVFCEKPLGMN
                     VQEVIEMVRAAERSHAIHQVAFTYRYLYGVQELKCRLLKGDIGEPYHVRV"
BASE COUNT         9456 a        11457 c        13733 g         9763 t
ORIGIN      
        1 aaggaaaaaa gcattcgggt cacggtattt ctgaacgtgt ttgacgtcca tgtgaaccgg
       61 atgccttgtg ctggaaccgt cgaaggggtg aattatcagc ccggtcagtt ccttgtggcg
      121 agcaagccgg aagcgacgct gcataacgag cagaatgccg tgatgctcaa gaccgagtcg
      181 ggggcgaaag tcctgtgcgt gcaggtcgca gggctgattg cccgccggat cgtctgctgg
      241 gtcgggcaag gcgatcgcgt gcagcgtggt gaacggttcg ggttgatacg gttcggttcg
      301 cgaatggata cctttcttcc gctcgggtcg aagatttgcg tcgcgttggg cgaccgcgtt
      361 aaagggggcg aaaccatcgt gggggaactc cgatgaaatc accaactatg cgacctccgt
      421 ttgcgaaggg gcaccggaag cggcaggcga tgtacctgat tcccaacctt tgtacgacgg
      481 gcaatttatt ctgcggcgtg tttgccattc tgtccgtatt caacgggcag catttagtcg
      541 ccgccatcgc gatcctcgtc ggtatgattt tcgacatgtt ggacgggaag ctggcgcgat
      601 tgacgaacag caccggtcag ttcgggatcg agtacgattc tctttctgat gtggtgtcct
      661 tcggcgtcgc gcccggggtg ctgatttact cctacgccct gagcgggcag ggcatgtttg
      721 gtgtggcggt catgtttgcc tatgtcgcga tgggcgctgt gcggctcgct cgattcaatg
      781 ccacggtgag tacgtcagac agcaaatact ttaccggctt agcgatcccg gcggctgcgg
      841 gtgtcattgc ttccctcgtg atctttgatc tccacatcac ccagctggga tcggaagtga
      901 aaccgctgct gattctggtg attacgttcg ggttggcatt tctgatggtc agcacgatca
      961 agtatcgcag cttcaaggac atgaagttcc ggcgaggcga tcatttcacc tatctcgtct
     1021 ggggcatttt ggccttgatg ttgattgtcg cgtggcctca agctatgctg ttcgtgacat
     1081 tcacggggta tgcagtgtca ggtccgattg cacgcctctg gacgatgatc gccaagagtg
     1141 caggcaagcc ggtcgcgaaa actgatggac cggtcgtcga aacaagagag tcgtaacggc
     1201 attgacgagg agtagtaggg agcggtagcc gaattgagag agctggtgga cggtgcgaac
     1261 cagccggttg cttcctgaac tcgcctccga gccggacttg tgaagcctct gatgaggtgg
     1321 taatgagtcc cgaatgatcc gcgtcacgga tttaatgagg gtgtccggtg aaggctggct
     1381 tcatccggcg ctgaatcagg gtggtaccac gaagctcgca aggccttcgt ccctgtccgg
     1441 ggcggaggct ttttttattg gcaccgtgct gaaacaggtt tccaactttg ttctcggctt
     1501 gaaaacatcc tcgacgtacc ccagcgggta cgcctccggt gttttcgtcg cctgcggccg
     1561 cgttggaaaa cccgtttgag cacggtgcag gacagaggag ggttgtcatg actcggatga
     1621 tcagaatatt cgacacgacg ttgcgggacg gcgagcagtc gccaggggcg agcatgaacg
     1681 tcgaagagaa gcttatgatc gccaagcagc tggcccgcct cggcgtggat attattgagg
     1741 ccggattcgc ctacagctcg cccggagatt tcgaagcggt gcgtcggatc gccttggaag
     1801 tcgaggggcc ggtggtgtgc agcctcgcgc gggctcgtcc ggaagacatt acgcgggctt
     1861 cggaagcgtt gaagggcgca ccgagagtgc gcatccatac atttctgtcc acgtcggata
     1921 tccatttgaa gcaccagttc cggatgacgc gtgaagaagc gaagaaacga gccgtggaga
     1981 tggtgcaatt ggcacgcacc tacgtcgatg atgtggagtt ttctcccatg gacgccagcc
     2041 ggtctgaccc agcgtatctc tgtgaagtga ttgaggcggt catcgcggcc ggtgccggaa
     2101 cgattaatat tcccgacacg gtggggtatg ccgttccaca agagtttggc ggcctgatca
     2161 aacgcatcaa ggacacggtg ccgaacagca gccaggcgat catttccgtg cattgtcaca
     2221 atgatttggg aatggcggtg gccaatagtc tcgccgcagt agtggcgggg gccggtcagg
     2281 ttgagtgcac gatcaacggt atcggcgaac gagccggcaa cacctcgctg gaagaaattg
     2341 tgatggggct ccggacacgc agggattggt acggcgccga cacgaaggtg gtgacggagg
     2401 agatctccaa aaccagccgc ctggtgagca agatcaccgg catggtcatt cagccgaaca
     2461 aggccatcgt gggcgcgaat gcctttgctc atacttcagg cattcatcag gatggattgc
     2521 tgaaggataa gaccacctac gaaatcatgc ggccggagtc cgtcgggttg gagcaggtca
     2581 agttagtgat gggcaagttg tctgggcgcc atgccttcag gcagcggctg gaagacctgg
     2641 gctacaagct cacggaagat gaggtcaatc acgcctttga acgcttcaag cggctggcgg
     2701 atcaaaagaa agagatttac gaggaagacc tcgaggtcat catctccgaa gaagtggcaa
     2761 agatgtccga acgggtggtc ctgaagtcgt ttcaggtcga aagtggaacg aataagacgc
     2821 caaaagccac ggtggaactg gagattgacg ggaaagtggt gtcgcacagc ggcacgggag
     2881 atggaccggt ggacgcggtc taccggacga ttgccgctat gacacaaacc aagagcaagc
     2941 tgctgatgtt cggggttaat gccattaccg gcgggacaga cgcgcaagga gaagtctcgg
     3001 tgcggctcga ggaagatggc cggaccgtct ccggtcatgg tgcggatacg gatatcatca
     3061 ccgcggccgc cagggcgtat ctgaacgcgc tcaataagct ggcgtatttt gcggcgaagc
     3121 aagccgaagg gattcacaag gtcagcttga tttgatccca acctgcaagg tagattcctc
     3181 cgtcctggtc agcacatggt gttggtcagg gcggggcgac atcttgtatt gccccctatc
     3241 gtcacaatcg gcacacgatg ttcagcacgc accttcaaca atgccctgaa tttctggcag
     3301 gcgatcacac gagattgcgg gaattgctgc atccgggaaa ggccgagctg gagctggggt
     3361 atagcctcgc ccatgggctg ctcgatccgg gcaagcagtc cctgtggcat cgcctgaaat
     3421 cgtccgaggt gtactacttc atcgccgggc gcggcgtgat gaaggtggaa gaagcctcaa
     3481 tgccggttca ggctggctcc gttatctatg tgccgccggg cgccaaacag tcgctgatca
     3541 atactggaac ggaatcgata gagtttctct gcctggtcga tcccgcctgg aaggcggaag
     3601 acgaggcggt cgttgaatag ttgagaggag agcgcgacgt gaaagcaaaa atcgcagtcc
     3661 tggccggaga tggagtcggc cgtgaaatcg ttcccgaagc ggtcaaggtc ttaacgaccg
     3721 tagcggagcg gttcgggcat acctttgaat ttcaagcggc agatgtgggt ggccatgcca
     3781 tcgataaggt cggagtgccc cttcctgcgg agacgctcac actcgcgaaa cacagtgatg
     3841 ccgtcttgct cggcgccgtc ggtggcccca aatgggaagg cttggattac agcatccgtc
     3901 ccgagcgggc gttgctgggt cttcgcgaac agctcggact ctatgcgaat ttgcgtccgg
     3961 cgaaactcta tcccatgctc gccgatgcct ccaccttgcg gcgggaagtc attgaaggaa
     4021 tcgatatgct cgtgatccgc gagctgaccg gcggcatcta tttcggcaaa ccgaagggcg
     4081 tggaaaaaat gcccggcggt ggagagcgcg gctttaatac ggaggtctat acgaccgagg
     4141 aaattcgccg gattgccgtg gtcgcgttcg aagcggcccg caagcgtcgc aagaaggtca
     4201 tgtcggtcga caaggccaat gtgttggagt cgtccgaatt atggcgacgc gtggtgacag
     4261 aggttcagaa ggactatgcc gatgtgacgt tgagccatat ctatgtcgac aattgcgcca
     4321 tgcagttggt acgcaatccg cgtcagttcg atgtactgct ttgcaacaat atctttggcg
     4381 atatcttgag cgacgaggct gcgatgctca ccggatcgat cggcatgctg ccctcagcca
     4441 gtgtcggcgc caaggtgagc ctctttgagc cgattcatgg gagcgcgccg gacatcgccg
     4501 gaaagaatat tgccaatccc atcgccacca tcgcttccgg cgccatgatg ctgtcctatg
     4561 catttcaatt ggacaaagaa gcggcggcca ttgagcaggc aatcgtcaag acccttgagc
     4621 agggattccg caccaaggac attcatgcgg aaggcatgcg gttggtcggg accactgaga
     4681 tgggtgatgc gatcgtgaag aaccttcccg cctaggccat gacgatcagc gccacaccat
     4741 ccgcaatgat tgcaaccctg gcagggaacg gcgagcccgg atatgccggt gacgggggac
     4801 ctgccgcagt tgcctcgttg aatgagccga aagggctttg catcgaccgc gaagggaatg
     4861 tgtatatcgc ggattctgaa aatcacgtcg tacgccgggt cgatcggaaa acaggcctga
     4921 ttacgacggt cgctggagtg ggtcctggcg gaacgggtgg ggccatgatg gcgccggaac
     4981 ctgttgcgat gccaccccaa gaagaagagg atccttttgc cgacacctcg ggggacagca
     5041 ccaaggcgta cacgcaggtc acggatctga gcggcaccgt ccggtatgtc accgggggac
     5101 ggctgacgat tgagcaggaa tcaggagacg gcggaccggc tcgccgcgcg aggctgaatt
     5161 tcccgagtgc cgtggctgtg gatcgtgcgg ggaatctcta cattgccgac acgatgaatc
     5221 atcgcgtccg gaaggtcgat gcgaaaaccg gcatcatcac tcacgttgcc ggcacaggtc
     5281 aggcgcggta ttccggcgat ggcgggccgg cggtccaggc ggcgatcaat gagccgaccg
     5341 gactggctgt gaccgatgat gccttgtaca ttgcggatca gagcaataat cgcgttcgcc
     5401 gggtggactt cgcgaccggg gtcatcacta cggcggccgg cgatggatcg gccgcctaca
     5461 gcggcgatca ggtgccggct gtgcaggcca gtttggcagg gccgagtggt gtggcggtag
     5521 gcaatgacgg tctgttgtat gtggcggaca ccttcaacag ccggatacga tcggttgatc
     5581 cggcgacggg gcagatcact acggcggcgg gagacggcgg cacctaccgc tatcagggcc
     5641 ctgaggagcc tgcgtcccca agtctttccc gtccggccgg tctggccgtt gactatgacg
     5701 gcaacgtgta catcacggat tctgatagtc atttgattcg agtatggaat gggcgcacga
     5761 aaaccatcac gcgcgtgtca gggaccggcg tcgcgcagtt cgggggagac ggcggcaacg
     5821 cgttggcagg cagtctcagt tatccattcg gcgtagcagt cgatgcggcc ggaaccgtgt
     5881 atgtggcgga tacgttcaat caccgcatca gggttctcac ggcgactgcg taaggacagt
     5941 atcatgttga agaagaaaca ggcctatacg gtggcggtgc tgggggcgac cggagcggtc
     6001 gggaaagaaa gtctcgagat tctggaagaa cgcaattttc cgattgagac gctgcggctt
     6061 ttttcgtcga agcggtcggc cggcgaggtg ctcacctgtc aggggaaaga gtacaaggtg
     6121 gaggaactga cggaggcctc ctcgtttgcc ggagtggaca tcgcgttcat ttccgctacc
     6181 gatgccatta gccgggacta tggcgcgcga ttgggcgcgg cgggtatcgt ggtcatcgat
     6241 gacagcgccg tcttccggat ggatccggac gtcccgcttg tcgtgccgga ggtgaatgcg
     6301 gcggcgctgc agtctatgaa gcgcggcatc gtggcgattc ccaactgtac gacgactccg
     6361 ttagtaatgg cgctcaagcc cctgcgcgat gttgcgggga tcaaacgcgt cgtcgtcacc
     6421 acctttcagt cggtgtccgg aactggttcg gccgccatgg atgaattggt ggaccagacc
     6481 aaggcgctga tctcctttca ggatgtgaaa gtgcaagtct atccctatca aattgccttc
     6541 aacctcttgc cgcaagtcgg gtcgttcgga gacggtgggg attgttcgga agaggtcaag
     6601 atcgtccagg agacgcgcaa gattttggac atgcctacgc tccgggtcac ggcgacgact
     6661 gtgcgggtcc cggtgctgcg ctgccattcc gaagccatta acgtggaact cgagcgtccg
     6721 atgaaagcca atgatgcgcg ggcggccatc gcggaaatgc caggggtgat tgtctatgac
     6781 gatccggtga aaaaactcta tccgatgccg ttcgatgtct ccggcaaaga cgaggtgtat
     6841 gtcggacggg tgcgcgtgga tgaatccatc accaatggat tgaatctgtg ggtcgtcagc
     6901 gacaatctcc ggaagggcgc cgcgctgaac gccgttcaaa ttgccgaatg tttgatacaa
     6961 tgatctatgg gtgcttggag cgggatcggc cggctgttca tcgttgccgg gttggctctg
     7021 gccggcgttg gaattctcct gacgttgctt gaacgatggt ccggtgccgg cgcggcgttc
     7081 ggatggatcg gccggttgcc cggcgatctg tcaattacgc gagaacgctt cagcctctat
     7141 gttccgatta caaccagtct tgtgctcagc attctgttga gcgtcgtgtt gtatatcctt
     7201 tcatggatct ttcgccgctg atcccacatc gtgcccggag tttcctcgca gcgggagtca
     7261 tggcgctcgc tgggatcgtc ttcgcgcagt ctgcctcagc cgaatccatt cgtgtcttac
     7321 tcgtacagga agcaccgttc gtagacgtgc ggtcggatgg gccgctggct cttgtgatgg
     7381 agacgggcga cacgaaaacc ctgcatggcc cgatccatct cacggcgcga gcggacgggt
     7441 tacatgttga tggccggcgt attctcggcg gacaggtgct catccgctcc ctgcggcaca
     7501 atctgaccct ggtcgtcggg aaagaaggag gatctgcagg cactccgctt ccgatcagtg
     7561 ggaccgtgcg agtgtcacgc aaagggcatg cggtcgcggt cgtcaatcag gtggatttgg
     7621 aggaatatgt gaagggcgtg gtgccatccg aagtcagttc ggcctggcac cccgaaatgc
     7681 tgaaggtgca ggccgtggcg gcgcgaacct acgcgttata caacaagatg ctcagcgcgg
     7741 cacgcgacta tgatgtcatg gcgacgattc aggatcaggt ctatcgggga cgtaccgggg
     7801 tcgatcatcg agtcgaagag gccgtcgaat caacccgagg gatcgtcgtc acccatcaac
     7861 aggcgccgat ttacgccgcc ttttcctcaa ccgcggcggg cccgactgaa gatgcggtga
     7921 atgtgtgggc caataaagat ctcccgtacc tcaagggggt cgaatgtccc tttgatctgg
     7981 agtcgccgta ttatcagtgg aaggccagtg tgaaaatcga acagcttgag aagaatctcc
     8041 ggcaccaggg atttgcggtc ggaaccattg ccacgattac gccgattgcc ttcagtcgtg
     8101 cgggaagagt cgcgcgtttg cggattttgc attccggcgg cgagacgctg ttgcggggcg
     8161 aagatctgcg gaaggccgcg gggtatactg tcatccccag tacgcaattc gaggtggaat
     8221 cgatcggtgc cgaagtggtg ttcgccggat acggcgcagg ccatgcggtg gggctgtgtc
     8281 agtggggcgc aaaagaattg gctgaactcg gatattcgta caacagtatt ctgcagtatt
     8341 actatcctgg aactgaatta cgaaactcgg ccttatcgca gttgatgatg ccggttattc
     8401 caaccccctg atgttactca gcgagtttga tttcccattt gatccggcac ttgtggccga
     8461 ccgtccggta ctaccccgcc atgatgcgcg cctactggtc atggaccgca gcagccacgc
     8521 acggatgcac cgccgggtgg cggatcttcc atcgctgctc cagccggggg acctgattgt
     8581 ggtgaataat accaaggtca tgccggcgcg ggttccggcc cagacgcgct cgacggggaa
     8641 aattctcgat ctgctgttcg tgcaggatct gggacagggc ctgtgggagg tattgatcaa
     8701 aggacggttc aagccgggag cgttcattga ttttcccggc ggcggatgcg gcgaaatcgt
     8761 ggagcggagt caggccagga cgaccgtcaa ggtgactggt gtgacgagtg tgtatgatct
     8821 catgcacaat accgggacga tgccgctccc gccctatatc aaacgcgagc cctcgcagga
     8881 cgatcagcgc tggtatcaga ccatgtttgc gcaacaggag ggcgccattg ccgccccgac
     8941 tgcgggactt cattttacgc ccgaattggt ggagaccctg accggcaagg gcatggagtt
     9001 ggcggaggtg acgttgcacg tggggcccgg cacgtttcgc agcgtgaaga gcgaccggat
     9061 tgaagagcac cggatgctgg ccgagcaggt ggaggtgact gctcgtacgg tcgagcagat
     9121 tcgcctggcg cagaagcgag gaaatcgagt ggtggcggtc gggaccacag tcgtgcgcgc
     9181 attggaaacg gcaggccgag gaggtcgtgg catccagcct ttccagggtc cggccgaatt
     9241 attcatcacg ccggggtttg aatttcaggt gatcgacgcg ttggtgacca atttccacct
     9301 gccgcgaaca acgctgctga tgctggtgtc cgcgtttgtg ggactggagc cgcttcgggc
     9361 tgcctatgag gaggcggtgt cggaacggta caggttctac agttacggag atgcgatgtt
     9421 gatcgcggga ggactgtccg ccgctacata agctctttgt ggatcttcac gggaactttg
     9481 ctcttcatcg attccgaata agccatcaac gcccgctgct gcttctggaa cagcagattc
     9541 tggaaaatcc gttccttcgc aatcgccgct ttcgtcggat cagattctcc ctcgcgtgag
     9601 acgagcgtct gtgcctctgc atattcagaa ggcgttaacg cgacggcatc catgatgacc
     9661 aggcgggcct tgttggtgag aatatccttg gcttccatgg cttcgaacga ggcgggggtc
     9721 aagcgatttg ctgccagcag tcgccgatag gactcgggat cgaagttccc attcttctga
     9781 aactccgttc gctgcatgat ggctttccgc aaatcttcat cggagaccga gagtcccatt
     9841 tctttggcca cgtgcagcca catgcgatta tcgatcagtt gttccagcac aaactgcttg
     9901 aggaattcat ccttgatgtc gttctggcct ttgtctttgt agaagcgata cgtattttca
     9961 taggcacggc gatattcatc cagcggcacg acctggtccc cgaccgacgc cacgacattg
    10021 ccgctctggt caccgaatcc ccaccagccc atcgtaatga cgaacgccag ggccagcgtg
    10081 cccatgatgg atttgagaaa ccacgggtaa tcgtgtgcag cttcgcgtaa taatttgatc
    10141 atcgaatgcg cctcttctcg gcagggtttc gcggattcta ctcaggcgac gacagcaaag
    10201 gcaagaggaa gaagtgcgcg gagagcgggt gcgagaagat tgcgactttg tttgtgcagg
    10261 tcaaagagat ttgctatagt gtcgaagaat tggggagatt tccggtggcg gaggaggcaa
    10321 tcgggcgcag cccggtcgaa ctgggcgtct atcccaaggc ccaggtgctg aatcgcttca
    10381 tcgcgaaaat gatcgatctc ctgatcgtgg cggcggtgag caaactggtc cctcccatcg
    10441 gtgtcctggc cggacttgcc tatattttgt tgggcgacgg gtttggtggt ggtcgcagtg
    10501 tcggaaagcg gctgatcgga ctccaaacca tcgttccacg tacgcgggac ccggcgggat
    10561 tccgggagtc gatcattcgc aatctgccct gtggtcttgc tcagttggca tttgagatac
    10621 cctatgtggg gtggatcgga tggggcgcgg tactctcgct agaaggatta ttggtcatcg
    10681 gcaatgagca aggccgccgg ttgggcgacg aaattgccaa gacgcaggtg ctggagagcg
    10741 gacagctgga tgtatcggac tgaatggctc gatgctgctg aacgaagcaa tcgtgtgaag
    10801 ggagagttct agtggccttc atgagtgata tgttcggatg gttctccaat gatctggcga
    10861 tcgatttggg gacggcgacc actctcgtgt acgtccaggg gaagggcatt gtcctcaacg
    10921 aaccttccgt ggtcgccgtt gagaaaaaga cggaacgtgt catggccgtc ggcgccgacg
    10981 cgaagcgcat gttgggacgc acgccgggaa atatcatcgc ggtgcgtccg atgaaggaag
    11041 gcgtcattgc ggatttcgaa aaagccgaag cgatgctgag ccacttcatt cagaaggctc
    11101 acaatcgcac ggcattcgtg cggcctcgca tcatcatcgg cgtaccctcg cggattacgc
    11161 aggtggagca gcgggccgtc cgtgattctg ccgaactcgc cggtgcgcgt gaagtctatc
    11221 tgatcgaaga accggtggca gccgccatcg gggccggttt gcccattacc gaaccgtcgg
    11281 gaaacatggt ggtcgacatc ggcggcggca cgaccgacat cgcagtgatc tcattgggcg
    11341 gcatcgtcta tagcgagtcg gtcaaagtgg ccggcgacag aatggacgat gccatcatga
    11401 actacattaa gaagaaatat aatctgctca tcggcgagca catggccgaa cgcatcaagt
    11461 tcgaaatcgg gtcggcctat cctttcgaag agcggaagac catgatgatc aagggtcgcg
    11521 acttgatctc cggcattcca cggacgttgg tggtggatga tgccgaagtc agagaagcgt
    11581 tgcaggaacc cattggaact atcgttaatg ccatcaaggt ggcgcttgaa aacacaccgc
    11641 ctgaattggc cggagacatc atcgatcgcg gtatcgtact gactggcggc ggatccttgt
    11701 tgaagggaat ggacactcgg tttcgtgagg aaaccaatct tccgatcatt acggtcgatg
    11761 acccgctgac ctccgtggtc ttgggcgtcg ggaagattct cgatgagttg gaccttcttc
    11821 gcaaggtttc ggttatgtcg cagtgcagta cctctcgatg acctccatcc cgagtgtgga
    11881 tggctatatc gcgctcaaca tacggcaccc ggcgtcttgc tatcgtcttg ttcgcctgcc
    11941 tgctcgtcgc cctctttctt ctccctagtc aaagccagag gttgctgcag tacgtcggtg
    12001 gaccgctcgg tcaagtcctc agtcttccac tcgccgcatt ttcctccgtg gatcatggca
    12061 ttgccgacat gtggaacggt tatgtcgcct tgcagacggt gcgtgaggaa aatcgccagc
    12121 ttcatcgcga catcgagtta ctcaaaggac agaataatca gctgcgcgag tccatgacag
    12181 ccgtgcaacg gtatgaggcc ttgctgaatt ttaagcagca atcgccatcg cagaccctgg
    12241 cggcgcaggt gatcgggcgg gatgccacga actggtaccg cggaatgatc ctcaataaag
    12301 gcgagaatga cggagtgaga acggaaatgg gggtgatcac ccctgccggt gttgtcggtc
    12361 gggtggtgaa aaccaatgcg acctcgtcgg tggtgctctt ggtcacggac ccgaacaatg
    12421 cgattgccgg cgtcgtgcag cgaacccgtg atgaaggtat cgtcgaggga accagtcatg
    12481 ggcgcgcgcg actcaagtac atcccgctgt tatcgaacgt tcaggccggt gatcgcgtgg
    12541 tgacgtcggg tctgaccggc gcgttccctc gggggctggc catcggaagc ctgattcagg
    12601 tcgaaaagtc agaaggggat ttgttccaat ccgcggaaat cgagccggaa gtggacctct
    12661 ccaaactgga tgaggtgttg atcatcaccg ctccctatga ggatgccgac gccgcgcaga
    12721 aattgcttca ggccattcat ggagacagaa aaaagccatg aagttcctgt tgtacctcct
    12781 gctggcgctg gtggtggttc ctttgcaaac gacattgctg cattacgcca gcgtattcgg
    12841 tgtgcggccc gatctcgggc tgatagcggc ctgcctggtg ggatttctcg gcggagagct
    12901 ggacggttta attctcggcc tcattctggg atgttttcaa gatatgctgt cagcaggaga
    12961 tttgtggatc aatgtggtga ccaagggcgg aagcgggttc ctggccggcc tggccgggag
    13021 gcatatggcc cacatcactc cggctgtcat gacggccggc ctcgccatca tctcctgcct
    13081 gtcgagcgcg gtctttctct attcgatgaa tcccgcaggg ctggatgaag tctggttggg
    13141 cgtgcggtcc accgtgctgg tacaggccgg acttgacgcc gctctcggcg cgggcctgta
    13201 tctgttgttc cgtcaacgtt ggtctgatga tcgtatggtc acggagggag ccctctaaat
    13261 gaggaacggt ctctggcaag agaccggcgc agggcaacga tggcgacagt aggattcaac
    13321 gactccgatc ttctcgatct tcagcggcga ctggtcattc tgcgtgtggg cttgctgttg
    13381 gttgtggcct tgctcgcctt gcgcctctgg catctccaga ttcgggaagg cccctattat
    13441 cgggatttgt ctgagaataa ccgaacgcgt tccgtggtgc tcgagccggc gcgcggactg
    13501 attttcgacc ggaacggcgt gttgctggcg aacaatgtgc cgagttttgc cttgtacgtg
    13561 acgctggagg acgtgaagga tcgtcaggcg ttagttgggc aattggcctc gcttctggcc
    13621 ctcgacccgg aagtgattca gaaaaaactg tcgaccggca agggcggaaa attgcagcca
    13681 cgcaaggtca aagaccggct gacattgcgc gaggcgaccc tgatcgagtc tcaccgcttg
    13741 gacttgcccg gggtaatgat tcaggtggaa tcgcagcgga actatcccgc gggcgctgtg
    13801 gcggcgcact tgttggggta tgtcggggaa gtctcggccg atcaacttga aaagccggat
    13861 ttcgcagatc tgcaccaggg tagcatcgtc gggcagtatg gcgtggagaa gtggtttgac
    13921 cggcaggttc gtggccgcgc ggggcaaaag agtgtcgaag tggacgcgct cggccatgag
    13981 aagcgtgcca ttgtgtcaga caagccgctc gcgggtgacg acctctatct gaccatcgac
    14041 gccaagctgc agaaggtggc tgaagacctg ttgggtgatg aatcaggcgc catcgtggct
    14101 ctcgatccga cgaatggcga tattctggcg atggccagtc gccctgggtt cgacccgaac
    14161 gtattgtcca aagaattaac gaacaagcaa tgggtcgaaa ttgtccagaa cgaacggcgg
    14221 ccgctgaaca atcgtgcgac gcagggacag taccctcccg gatcgacatt caaggtcgtc
    14281 atggccgcgg ccgccctcga atcgaacacg gtcacgcctt cgacgatggt gcgttgcaat
    14341 ggcggctatc agttcggcaa tcgattgttt catgactgga aacagggcgg gcatggatca
    14401 gtcgacatga atgaagcgtt gatccactcc tgcgatgtgt atttctatac cgttgggcag
    14461 cggatgggca tcgacacgat tgctgaatat gcgaagcaat tcggactcgg acaggagaca
    14521 ggagtcgagt tgccgtcgga acgtgtgggc atcgtgcctt ctaccgcgtg gaaacagaag
    14581 gcgcgtaatc agccctggta tccgggcgaa accatttccg ctgcgatcgg gcagggatac
    14641 gtcacggtga cgcccttgca gatggcgagt gtgatcggca cggtcgcgaa cgacggtgtg
    14701 tcgatcaagc cgcgcctggt acaggccgtg atgaaccgca cgacgggaga gcgggcagag
    14761 tttccgccca cggtgcgcgg aaaagtggca gttaaaccgg ccaccctcgc gctcatcaag
    14821 tcggccttgg ccgacgtggt gaccaaagga acggcaacgc gagcaaagtc tccattggtc
    14881 acgatcgggg gaaaaaccgg caccgctcag acggcggccc tccgtaccgg gccggagaaa
    14941 gacattccaa aaaagtttcg tgatcatgcg tggttcgtcg cctttgctcc cgtggaagcg
    15001 ccgcgcattg ccgtcgccgt cctcgctgag cacatggggc acggtggatc ggctgccgcg
    15061 cccttagcga aggacgttat tgaagcctat gtgaaagcct atccccaggt actgcagggg
    15121 gcaccggcaa gcgggcgggc caagtcgcct gcggtgccgg ttgatacgcg gccgaagacg
    15181 tgatgattga tcgggtgatc gacagtcggg ggttggatag tttcgatctt cgcttcatgg
    15241 ggctgatcgc cgtcatcctg tcggtcgggg tgctgtcgat ctatagcgtg acgcactctc
    15301 aggacaccgc ctttcctttc tatctcaaac agctggtctg gattctgctg ggaaccgtcg
    15361 cgtttctcgt gatgtatctc tccgattatc acaagattgc acgcctggcg tacccgacct
    15421 acgcggttat tttaatcatg ctcgcggtcg tgttgttcat ggggaaatcg agccgcgggg
    15481 ctcagcgatg gattcccatc ggaccatttg cgtttcaacc gtctgaattc gcgaaactgg
    15541 tgctggtgct ggtgctggcc aattattact cccgggcatc gcgcgtggga tggctgcatc
    15601 gggtggtgtt gccgggcttg atagtgttgc cggggctgtt gttgatcctg aagcagccgg
    15661 atttgggtag cggattgagc tttttggcgg tctatgcggc catgttattg atggtcggcg
    15721 tccggtcgaa ggcgttgggc atcattttgt tgctctccgt tatgctgttc ccgttcgtct
    15781 gggaagtggt ctgggcctcg ctgcacgact atcaacgcga acgggtcatg gccttcgtgg
    15841 atccggatta cgatccggga ggcaaaggct accatgcgtt gcaatcgaga attgccattg
    15901 ggtcagggga actgtcgggc aaaggattgt acggcggcac acaaagtcag ctgaagttcc
    15961 tgcccgaagg gcatacggac tttgtattcg ccgtctatgc ggaggaatgg ggctttgtcg
    16021 gcgtcctcgt cctgctggct ctgtttatcg cattgatatg ggtgtcattg gaaattgccg
    16081 cgcgtgcgaa ggacacgctc ggggcgttac tcgcggccgg tatcgtcgcc atgttgtgtt
    16141 tttgcgtggt cgtcaatatc ggcatgaccg cagggatgtt tcccatcgtc gggattccgc
    16201 ttcctctggt gagttatggg ggcagcgcga ccatcatgac gatggcgtca ttgggtttgt
    16261 tattgaatgt gaagcgacgt cggctgaccc tgttttacta ggcgatgcct ggacagcggc
    16321 cgacttgttg tgaaataacc atgtgaacca gaggggcgtc gggctgccgg cgagacgaga
    16381 gaacccggac atctgtccgc gtgcgtctcc caatccgatc catctggggt taaaggagtg
    16441 tgtatgggtg tggagatcgc aatcagtatc gcgcgggaag aaacccgcgt tgccgtcctg
    16501 gataatggtg tcgtgacgga tctctatggc gaccgggcca aggatcagga ttacgtcggc
    16561 aatatttata agggacgggt ggcgaaagtc ttgccgggga tgcaggcggc tttcatcgat
    16621 atcgggctgg agaaggcggc gtttatgcat gtctccgatc tgtctatcga tgtagagccc
    16681 ggagataccc tggtcgaagg cgacgacgaa gacaataagg attccgaagt tcccaagcct
    16741 aagcggcaaa gctcaaagcc catcgaagag ttgctgtctg agggacagga actcatggtg
    16801 cagatttcca aaggcccgat cggcacgaag ggatcacggg tcacgaccta tgtgtctttg
    16861 cccggacgat atctggtgtt catgccgacc gtggagcata tcggtgtatc ccgccggatt
    16921 cctcgcgatg aagaacgcgc gcgtttgaag gaaattatga aacgggcgcg gaggccgggg
    16981 ttcggctaca tcgtgcggac ggtcagtgaa ggggtgaagg aagaagaatt gcgctccgac
    17041 gtcgagttcc tgcatgtcct ctggcaggac gtgcttacca agcgtgacca gcagcccgcc
    17101 cccagcctct tgcatagcga tttgagcctg agctttcgcg tggtccggga tctcttcggc
    17161 cgtcgagtcg atcgcctatt gattgattca cgcgaggaat acaacgcgat caaggggttc
    17221 gtgcaacggt tttctccgga gcagacgtcc cgcatccact tctatgacaa ggaagaaagc
    17281 ctgttcgatt acctgggggt ggagcaggaa atcgcccgcg cgatgagtcg aaaagtgtgg
    17341 ctcaagtccg gggggtatct ggtgattgat cacaccgaag ccatgacggt gatcgatgtg
    17401 aataccggcc ggtttgtcgg caaacgggat caggaagaaa ccattctccg gaacaacttg
    17461 gaagcggcac gggagattgc ctaccaagtg aagttgcggg gcattggcgg gatcatcatt
    17521 gtcgatttca tcgatatgga gcgggaaaag aaccgcgaca aggtctatca cgccttggtg
    17581 gatgccatgt cttcggacaa ggcccgaacc agaatttccc gcgtgtctga tcttggattg
    17641 atcgaaattt cccgtgagcg ggtgcgcgag gatctgctgc ggtcactctc tgaaccgtgc
    17701 cactactgcg acgggcgcgg gtatacgaaa tctcccatgt cggtggccta tgaaattttc
    17761 agggaagtgc ggcggctcgg tcacgagatc gagcagcaac gtgtcgtcgt cggggcgcat
    17821 cctgctgtcg ccctgctgtt acaggagcag gaacagcccg gggtagagga actcgagcgg
    17881 cggtatagcg ccaagattct tgtgactccg gatgatcgtc tacatctcga acagttcgac
    17941 ttagtcgtca tgtaatacag caaggcgccg ccctggctgg ttttacgcga acgtctcgtc
    18001 tctgacagcg cttccagcac cacggtcact gagtcgcacc gaccatgcct gatgaactca
    18061 gacgatggtg aatagtctat ctctccgccc atggctgatg ctccgtgcga tccctggtgt
    18121 gggcgatgcc attctgctca agctggtgca ggcgatgggc tctccggacg cggtgctgtc
    18181 ggcaacgcaa gcgagcctgg aagacgtcgg gtgcagagtt ccgttgatcg acgccattcg
    18241 ccgtgggcct gacgcacagg cggtcaaaca gcttgatcgg gaactggcgg cggtgcagca
    18301 tcgtcagatc accgtgctga cgtatctcga tccgcagtat cctgcgcctc tcaagacaat
    18361 tccggaccct ccgccgctgc tgtatgtcca gggaaccctg ctggaaagtg atcggcaagc
    18421 cgtggcgata gtcgggacca ggaaagtcag ttccgccggc cgggtgctag ccgaggaatt
    18481 ggcctgtgag ttggcggaga tgggcttcac gattgtcagt gggttggccc gcggcgttga
    18541 tgctgccgca catcgcggag cactcgccgg caagggacgg acgcttgccg tgatgggatg
    18601 tggattggat cgcacgtacc cggccgatca tgccgcgctc cgccaggaaa tcgagcggca
    18661 cggggcggtc ctctccgaac tgccgctcgg gtccgcgccg cacagctacc acttcccacg
    18721 ccggaaccgc atcatcagcg ggctgtcgtt aggcgtcgtg gtgaccgagg ccgcggttga
    18781 aagcggctct ctcattaccg cgcgattggc cggtgaacag gggcgcgagg tgtttgcggt
    18841 gcctggcttt gtgaaggccg agaatagtcg cggaccgaat agcctgctca aggatggcgc
    18901 gaggctcgtc gaatccgcgc aggatattct ggatgaattg ttgcctcagc tggatgccgc
    18961 gtttcgcgaa cggctcggcg atcgcgcgag aggagcccga ccggctatgc aattagggcc
    19021 cgaggaagcg atggtatatg atgccgtatc ggtattgccg caatcggtcg atgatgtcat
    19081 tcgacgcagc gggcttgcgg ccgcgcaagt caccgcagtg ttgctgtcct tggaattgaa
    19141 aaattgtgtc cgccagttgc ccggcaacga gtatgtgcgc ctctgagtgg acccgttgag
    19201 agattcaagc tgacagggtc tcgatatttg ttatagtgag tgtgatagtc tgggcgcagg
    19261 tacttaggaa catggagcca catggccaaa tctctgatca tcgttgagtc gcccaccaag
    19321 gcgcgaacca tcaccaagta tctcggacga ggatattccg tcatggcctc cgtggggcat
    19381 gtcaaagatt tgccgaccag taaactgggc gtcgatctgg agcatgactt tgaacctcag
    19441 tacgttacga tcaagggcaa atccaaagtc cttgcagaca tcaagaaaaa agctcagcaa
    19501 gtggatacgg tcttcttagc gccggaccct gatcgtgaag gggaggcgat tgcctggcat
    19561 atcgcgcagg aactgcacgg caagggcaag aagaaagacg gcaaggtcta ccgtgtgctc
    19621 tttaacgaaa ttacagaatc ggcgatcaaa cgcgcgctga agtcccccgg tgaaattgat
    19681 atgaagctgg ttcaggcgca gcaggcgcgc cgggtgcttg atcgtatcgt agggtaccag
    19741 ggcagtcagt tgttatggaa gaaagtgcgg cgcggtctca gcatgggacg cgttcaatcc
    19801 gtcgcggtgc ggcttatttg cgaccgggaa caggaacgcg aaaagttcag agccgaggaa
    19861 tattggtcca ttgtcgcgct cttgcgtgga gacaatcctc cggctttcga ggccaagctg
    19921 cattccatca acgggcagga tgccgatatc ggtacgagtg cgcaggccga gcaaatcctc
    19981 aatgccgtgc aaggcaaagc atttgtcgtt caatccattg agcggaaaga aaaaaagcga
    20041 aacccggtcg cgcccttcat caccagccga ttgcagcagg aagccgccag gaaattgcat
    20101 ttcaccccga agaagaccat gacgctggcg cagcaattgt atgagggcgt ggaaatcggc
    20161 gcagaaggcc cgatgggtct cattacgtat atgagaaccg attcgccgag aatctcccaa
    20221 gaggcgaccg aagatgcgag gctggtgatt cgcgagcgtt tcggagagga gtatctgccg
    20281 gcgactccta atgtgtacaa gacccaaaag gcggcccagg aagcgcacga agccattcgt
    20341 ccgacgatgg cggctcgcga tcctgaatcc atcaggcaat ttctagagca ggatcaatac
    20401 aatctgtaca agctgatctg gaatcggttc attgcctcac agatggtccc ggctatcttg
    20461 gatgtgacgc gggtcgattc cagtctgatc ggaacaccag aacgctacgt gtttcgcacg
    20521 accggcaccg tcgtgaaatt ccccggccac acagccgtct acctggaggg gaccgacaag
    20581 gaattaccct cgcagaagcc taaaagtgag caagagtcgg aggacgagtc ggaccggcag
    20641 cttcccgtac tccgtgaagg agagtcgctg catctggtca ctcaggaagc acagaccctg
    20701 ccgggcctta tctcaaagca gcatttcacc cagccgccgc ctcgttacaa cgaagcgctg
    20761 ttgatccgtg aactggaaga aaagggcatc ggtcgcccat cgacctatgc cgccatcatt
    20821 tctacgattc aggatcggaa atatgtcgag aaggtcgagg gccgtttcct gccgaccgaa
    20881 acgggtcgga cggtcaatga ctttttgctg aaggggtttc cggatctgct ggacacagaa
    20941 ttcacctcgc atatggaaga gcaactcgac gaagttgaag agggaaccaa gccgtgggtg
    21001 tctgcggtga gggagtttta tgcccccttt gtcagggaaa tggagctggc gcaaagtatt
    21061 cccggcccca aagacatcgt tgagcccccg accaacctgc cttgtgaaaa gtgcggccgc
    21121 atgttggaga tcaagtgggg gcgaaacgga aagtttttgg cctgtcctgg atataaggaa
    21181 gatcctccct gcaagaatac gcagaacttt gaaaaacttc ccgacgggac aatcaaaatc
    21241 gttcccaagc tggaggagac gaccgacgaa aagtgtgaga aatgttcaag ccccatggtc
    21301 gtcaaatctg gccgcttcgg aaaatttcta gcctgttccg cttatcccga atgcaaaacg
    21361 acgaaagcca ttgccttggg ggtgaaatgc ccacagcctg gatgcggtgg ggatctggtt
    21421 caaaagcgca cgaaaaaagg gcgaaacttt tattcgtgta gccgttatcc ggagtgcgag
    21481 tttgcgcttt gggatcggcc gattaataag ccctgtccca agtgtcaggc cccgttcctc
    21541 attgagaaag tcagtaagca agccggccgc tctgtgcagt gccgtaatga agaagagtgc
    21601 ggctaccgcg aggccggata atctcgacgc acggtctgcc cgtcccaagg ttgtttctca
    21661 ccttccttgt tcttcaatcc cgatcgaccg aatctccatc tgcactgtac cgatctgctc
    21721 gcgcgaggac acgtgttctg atgaggacaa tgagaagcgt tctcggcgat gttgagaacc
    21781 gccctcataa atacgtatat caatggttga caagcccttc gagaatctct aagtaaggag
    21841 tacaataatg gggaagcagg aattgcgtag cgactaaacc agatactagt ccataggccg
    21901 tgagacgtta tggccggagg agggggatat gaaggcaaag caaggcgtta ttgagctgct
    21961 gaataaagtg ttgacggcgg atcttaccgc catcaatcaa tatttcgtcc atgcaaagat
    22021 gtgcgccaat tggggctatg aacggctcca tcacaaagtc agggagcgca gtattgatga
    22081 gatgaaggat gcggacgaac tgatcagcca cattttgtat ttggaaggtg tgcccaacgt
    22141 tcaacgcatg aacacggtcc atattggaga gaccgttccc gagcagttga agctcgacct
    22201 gaaggccgag caggaaatgc tcgccctatt gagtgaagga gtagtgcatt gtacgaaggt
    22261 cgcggatttt acgacgcggc acatgttcga agatatggcg aaggatgtgg atgaacatat
    22321 cgattggatc gagactcaga tggaaacgat caagcagata ggcctcgaga attacctcgc
    22381 tgagcagatc aagaaagaca gttaaacccg cgccggaatg gtgcagtgag gacatgggca
    22441 tgaaagcgaa agagggcgtt ctcgatattt tgaacaaggt gttggtaagt gagctcacgg
    22501 cggtgcacca gtatctgctg cacgccgctc tgtgcaagca ttggggctat gctcgactcc
    22561 acgagcactt tagccatttg gctcaggagg aggtcagcca ttcctccggt ttgatcgatc
    22621 atatcctcta ccttggcgga tccccggaga tgggacgtct ggatgccgtg gcagcgggca
    22681 agaaagtgtc ggagctcttc tcggcagatt tagcttttga gcgtgaggac gcagatgcgc
    22741 ttcgtcaagg catcgcacac tgcgcgaaag tcggggattt caccacccga catcggctgg
    22801 aagacatgat catcgatacg gaagaacaca tcgattggtt cgagacccag cttcgaacga
    22861 tcgaacaggt tggagaagat cgctacctgg cggaacaact caccgccgac aagtcctaac
    22921 cgcaaccgga agtgatggcg ggtcggcgag ctcaaacact ggctgacccg ccattctttt
    22981 attctcaccc tgcattccca gaccgcatca cttgttgagc tccgcctcaa gaagtctgct
    23041 gcaagccctg aatcgtttgt ctctgctgtc gagcaatagt caaacgaata gccatgggag
    23101 actgtcccgt tgctcgcttg aagaagtggc tgaaggcgaa ttgatcgctg aaccccagcg
    23161 ctgaagcgat ttccgtcagc gtctgtctgg tcgtgatgag gagcgcacgg gctcgttcga
    23221 ctcgctgtcg ccggagatat ttagagaacg gctcgcccat gatgcggcaa aacagatcag
    23281 agcaatattt ttcagaatag ccgaggaaat tcgccaagac cttcagcgtc acgccacgat
    23341 ggagattctc gtttacaaag gccgcgatgc gcgaaggttg cgtgtgaggg ataggcggag
    23401 gctgtgtttc cgggttgatg gcatgggaga ggttaaaaag atcacatatc aggtccccca
    23461 agtcctgttc cgttctgacc tgttccagcc ggtccgccca ctgtggcgat tgaactcgaa
    23521 gttctgatga gaaagagtgc aaccgatcaa atgaaatatt cgaggtagac gattttcctg
    23581 acatcatgcc ctccatcgag agttacaccg cccacggtaa cgagtaattt ggagatacga
    23641 ctggttagat gcctgagcct gtcatgtatg cttctggcac atgttctggt gacgattgcg
    23701 aatgcatggc gtcgctggag agatcggagc tctggtatgc ccggtagtga tcgtgattgc
    23761 gtagaagctc aatgaacgtg acgcagaacg ccggatcaaa ttgagagccg gcggaggcat
    23821 gaagcgttcg cagggcgctg tcccacgagt tggttcggct ggtgatgctg tcaaacacat
    23881 cggcaatcgc gagaattctc gctgaggcgg gaatgtattc gccgcgcagc ccgtagggat
    23941 atccggctcc gtcccaccgc tcatgatgat gggcaatcag ccgtgccgcc acttgaagaa
    24001 atgtataggg agtcagcagt gcggcccctt cgcgaggatg gctttggatc agggcatagt
    24061 cgttaagtgt atgaggagct ggcgcaccga gcagatgtcc cggcatcatg aggagcccaa
    24121 cgtcatgcag caatgccgca tagtgcaaat ccaggcgttg atgtttggta agcctaaggc
    24181 gatcggccag caataaggca taatgtgcgg tgcgttcccc atgtccgaag tgcccgggaa
    24241 tgacggtttc gatccgtcgt gccaaacgct caagttggat caccctgacc gcctcaagcg
    24301 actccgggga aagctgtaag gtattgaggg ctgagagctg cgtcgccaag tcttgaataa
    24361 gttgacttgt ggttggtatc ggtcgtgtcg aacgatgcat gaaagtcctc caaaatgtca
    24421 gagcccaaga ccatgtgaat ggtcttgggc tctgggcgaa atacctctgg ccgcacatga
    24481 gtggtgtaca tgccgcaatg ctaggtcatg cgtgttctcc gcgtttgcct gccattaacg
    24541 gttgtttcaa gatccacatc tcgtggagag gaatgacgaa catgatgaag aatcctgccg
    24601 tcatgaatgt atcgcctgtc agcatggtta agacgaagac gggagaaacg taactaatca
    24661 gccaaggcga taagaggtcg agtatgactc ctccgaagga aagccatgtc gtgactattt
    24721 ttagtcggtt actggcattg gtcaaataga ggacatggac aaggatcata aacacgaccg
    24781 gcatcgtgaa cagatggaaa tgggtaattt cagccagctc tcggaaagac atcggttcgc
    24841 cgaaggtggc attggagccg cggtaatgat cagcaatccc ttggggcgat aagccagtca
    24901 tgctgtgtgc ccagaaaaaa gagaacgtga agcctgcaag catcaacagg agaaagaatg
    24961 tgtagacgag cctgatatgg cgatccgaat cgcggaggcg aaaacgggta ttgaaattac
    25021 gcatgtctgc tgaaaatcag ttcccaaaaa tcgacttgaa gaagcccttc tccgtttttt
    25081 gagcggttac agtgtcgctg ccccgccctt ggggtttcaa gtaaaattcg tccacgagga
    25141 cgagaacgcg tttgatccct gccgtcatcg agcgaacgga catggtggcg ccgctgatgt
    25201 tgatgatatc tttgttaatc cgcactgggt cgagaacgga ttttccttca tattgcacat
    25261 taaatcgctt ggtccgtacc tcgctgcccc gcgcctcgcg aaaggtgagc aattccacat
    25321 tggaaaccag gccatgagca tctactccga ccatataggt catgggcttg tgtttgccga
    25381 tggtgttttg gaccagggcg tacccgtcaa tgtgtgtgcc ggtctcgcca atatagactt
    25441 cgaatgattc ctccgggaat ttccacccga tacggctttc gatcaatgct ttcttgtcct
    25501 ggggaaggtt cagcagttcc cttctcacgc gctccgattt cggaaacatg agtttgacgg
    25561 cttcttcttc agtaagaaag acttcggcca gggacatttc ctgctctgtc aaataacgtt
    25621 tgagctcatt gtcccataca cgctcggcct gggcgttgag tggagcgaga gcgaaggcgc
    25681 cggtgagagt gagcagcagc aataacggca tcataacggc gtacacccct gttgttttaa
    25741 tttttcgttc agtcgagtgg tcacctctgc tgtcgcctct tcggatggtt ccacgggcca
    25801 ccacttagtg gcctgggacg tgacccctcc tcgtgaatgc cagcgctggc gtgtttccag
    25861 cagactgacg gagacagcgc cattcgatgt cttgagggcg agactcatac gcgcgcgctc
    25921 tctgttccca aatcctgtgc gcccgaaaat gccataactg cgctcttttc catccatctc
    25981 cagccagccg gtctcgatga cgcctttggc tttgtcctgg gacgtgatcg agtagctttt
    26041 catggtatcc atcgcggcgt cccagacgac gtcttgtgag caggaataag actgctcgtg
    26101 actgccgctg agcgaggcgc aaccgatggt aaggaatgct gctgctgcga taaatatgtg
    26161 tgccctttgc acggaaatcc tgcctcttgt gaatccggcg gccctcccca tagagagagc
    26221 cgccggggtg tgaatttaga aatacgtcgc tgcagaaatc acgaatgcgc tgtcatgaat
    26281 gcgctgtcca gtattgggat taaacgattt cggcatgtat tggtagctgg ccttgaatac
    26341 ggcatcttcg atcggccgat aattgagacc gaacgaaaac tgctctaatt cgccagagtt
    26401 ttctccacga ttgtccatat tgagattgac ccggtcatat ctgaacacgg cggtgaatgt
    26461 tgatccctca ccaaagcgct tcggtgataa ggccgtgagg aacgcgggca tgaaatgata
    26521 gttcgcctgg acatagaatc cctgcatccg ctgcggaggg gcggcaaatg agttcaaggt
    26581 attaagtccg ctaagtagcg agccgggagt ggcgaaggtg gctccctgaa ccgcgcggga
    26641 attgccccgt gcataggccc aggccgcttc tcccaagagc tcgaatgggc cacgttggaa
    26701 ggtccaatcg atggcggtaa tgctgagggg gttgtagctc aggggggaag catttccgaa
    26761 gtagctggat ccggcaactt cgacaccgag catcgggctg aacgcgacgc ggccagagac
    26821 cgcctttccg ttgttgatat ccaacccatc ttcagagggg cacttgcgct gtcgggaacg
    26881 tcgagtgccg tcttcttcac gaatgcgagg gcttccgtcc ccgttatatc cgcatgggcc
    26941 ggtggtgaca tagaattcgt agtcaagctt gctggttcga cccgggtaca gggtgccata
    27001 aaagccggcg cccgtttcgg ccatcgtcga cggaatcacc agacgactga cgagtggtcg
    27061 atcggtgaga tcgttgagcg gcgagtcatg caacaggttg aacttcccga tcggaaccaa
    27121 aagaatgcct gcgcgaaggt tgaacggttc tttgaccaag tagtcgatgt gggcgaactc
    27181 caagccgatt tcggccccct gcgtggcatc ttcacgaatg ccatgctcga tttcaatttc
    27241 agcggcgaat ttcacatgct cggtgatgtc ggcatagatg aatggaacaa atcgttgttg
    27301 atcaaatccg ttggtggtcc cgcttcccat gcctgattca agaacgccat tgcggtgtga
    27361 acggtactgt atgtccatgt acccaccgac gatcgctttt ggcgcggcga caaacggctt
    27421 ggcataaacc aagcgtccag atccggtgga cccgaacgac aatgctgctt ggttctcggt
    27481 tcgacgttct tttccgactt ccggaaggga gccgataccc ggctcattac caggggcacc
    27541 cacagtttcc ctgtgatcgc cggcaccttc gcgacgttca tgctcctgca atcgcttttc
    27601 aaccgcttcg tcaaccagct tcttgatctc ctccggggtc atgttatctg ccaacgccgg
    27661 cattgccggt aaactggcca ggaccagagc cccgaggatt gcccgaatct tcatggggat
    27721 cctccatccg cgagtaaggt tatggtatga ctcgggactc aatggtctct ggtctgtaat
    27781 gaaagtctga gtgtggggtt gaagccctgg atattgtccg gtgatgaggc ctcctttcgt
    27841 gaatcgactc atgctggcac cgtaccccat ccttcgattg aggtaaaagg aatgaccaca
    27901 atgcgtttgc agcgcttgca tttaagctcg agcccttgtc cgcgaacttt ggcgatcagt
    27961 tgaccgcatt cgcagcgtgt ttcgctgtct tggcacaagg aatgtattgc gttattggtt
    28021 ggtgtcatag tgaagtgtcg agttcctggt attgagaacg attattaata tcccgatcag
    28081 tagggtaatg tcaagacgct tttgggaagg tgtgctgagc tcatcggatc ctgaggaaac
    28141 ggacgactta gcgggagatt agggattggg caggcacatg ggaggcggca tggtgaagcg
    28201 ggaattcacg acaatgccaa ggttgcaatt ttcctcagtg gcagagaaga tgactcgctg
    28261 cagattccca ctaaccaagg accatgccga tgaagttgtc cattaatagt caccccttgc
    28321 gagcatttct attcatgttc gtaaacgatg ctgtcctacg gcgcgggttt gctttggcaa
    28381 ttcggggaag cctggggctg ctattgttac ttgggctggg gtgcgcaggt ggaaaccttg
    28441 gaagctctcc cattctcgtc aagcgcaccc aaatgcatat gggtacgtgg gtgagcatta
    28501 cggcagtcgc cccagaccga gaggcagctc aatacgccgc atcggcagga tttcaggaaa
    28561 tacatcggtt ggaagaattg ttgagtactt ggattaaaga tagcgaactg tcacgggtga
    28621 atggagcagc gggtaaagaa gctgtctctg tcagtcctga tacgatgaag gtccttcagg
    28681 catcagttgc gatggctcgg cttaccggcg gtggcttcaa cattcttgtc ggccccgcgg
    28741 tcgaggcttg gagtgtgttg gatcgccagc agatcccgtc ggagtctgag ctagagaaca
    28801 tccgtcctct cacgaacttg aacgcgttgc aattaagcca ggcgcaggga accgtctatc
    28861 ttgcaaaacc gggaatgcgc gtggatgtgg gaggcatcgg taaagggttt gcggccgaca
    28921 tggcagtgga ggcgatgcaa aaagccggtg caacggcggg ggttgtggca ttgtcggggg
    28981 atatccggac atttggccaa atgcctgacg gaacgacctt tccattcggt atccgccatc
    29041 cacgtcgcga aggaacagta ctggcattcg tagatcttca gaatgaggca atttctacgg
    29101 cgggcgatta cgagcgctat ttcgagcggg atggagtccg atatcatcat gtccttgatc
    29161 cggtgacctt gcagccggca cgcgactgtc aaagtgtcac gattgtcgcc aaagacggcc
    29221 tgacggcaga tgggttggat acgggcattt ttgtgatggg cccagaacgg ggactcgcgc
    29281 tagtggaatc gttgcctggt gtcggcgcag tgatcgtcga tcgtgacgga aaggtctggg
    29341 tgtcctcatc cctcaaagga cgagttcgaa tcaaggacgg cgtcgactag tgttgtcata
    29401 ccttcagcgt gagtcccagt cggagaggcg agcgggaagc atgctgaacg aagggccggc
    29461 atcagccagg ttatggtcct agctggtagc ggatggggac atggagagtg accggtgatt
    29521 gttcgagagg ctgcgtcagc gcgatcggtg aaatctttcg cactgtttca agtgcggctt
    29581 gatcaagagt gtcatgcccg gaactttttg cgaccgcggc ggacacgatt tggccatctt
    29641 cctgaatcac aattcggacg accactctcc cttccacgtg cttgagccgt gcatccacgg
    29701 ggtactcttt gagcgcttca atgcgtggca agagaatgcc tgcaagccag ccataatcga
    29761 cctttctggg cgccgggacg ttgttcgctg atggggtgag cgcggcggtt gaggtcgggg
    29821 ctgggggctg ttcggtggat tgctgtgcag ctggaaaagg agacgttggt ggatctggga
    29881 cttcatgatc tttggctggg gaagtgactg gtgcttgctg tggatgaact tccgccgggg
    29941 aagggaccac tggcgcggga gaatggtccg ttgccggctc cggtcgggga gcttccactg
    30001 cctcaggaag aggccgcgcg agagagcgtt gaggtgccgg ctcgatattc tgaggcggcg
    30061 atggaacaac gggggtaggt gtcagcggtt catggatact agtgtgagag gccgggaccg
    30121 atttcgagga atgttgtaca tcggaggccg cggggcgcgg agagggtgtc ggcgtgctct
    30181 gcgctgtcat gcgcgcagga gttgagggaa cttgcggttt gtcgagcgtg ggagttgacg
    30241 cggatggggt gacgacggtc acgtcccact gaaacgacga ggatggcggg gggagtcgaa
    30301 tcttggcggc gaacagggtg gccaagaaga ccgctgcgcc gtgcaagcag agcgagatga
    30361 tccatccgct tgcccgcaag cggacgaaag cgtccggcat gccggcaggg ggagcggtca
    30421 caagcgcacg acctccaggc tgacagattg gaagcccagg ccacggatct catccacaac
    30481 cgaaacaaaa cgttccagca gcgtgacctt gtccgctcgc acgacgacca gagattcgcg
    30541 cgggtgggtc aacatcacgc ttttgaggcc atccgctgga acgggccggt cgttcaaaaa
    30601 cagatctccg ttggcggtca aggtgacgac gacggggaca tctttatgat cccccgcctc
    30661 ttttgccttg gcgaggttga caggaatttg gcccgtgctg atgaaggtgg cggtcgtcag
    30721 gacgatgacg agcagcacca acatcacatc caccagcgga atgacgttga tttgattaac
    30781 ctctcgttcc atgttgcacc ttataggtcg tcagcagttc agcgacacgt cggcgaagaa
    30841 tattgttcat gacaacgcag ggaattgcca caagcagacc gaccgctgtt gcctttaggg
    30901 ccaggctcag accgatcatg atggtattca cggccatggt tccggaggtc cccatcgtat
    30961 gaaaggtcat catgattcct aaaaccgtgc ccagcaatcc gatatacggt gcattggctg
    31021 cgacggtgcc gatgatgacg agtcgcttgg tcaacgccat ttcaaaggtc tgcacgtcgg
    31081 taaactgcgc cagattgacg cgtcgataat atagccaccg ctccactgcg accgcgactg
    31141 accacacgct cagcgcgatc aacaggccaa tgatcccata ctccaccgca tttttcagca
    31201 cgtccattcg ttgttcctcc actgttatcg ccggggggcc gcataacatc gttgcggatg
    31261 tccttctccg tcttgttcgg tctcgtgtca ggaagtgagt ctgatgtcac gccaccggcg
    31321 gagagccggg cggttgcgga aacaagaccg tatgggtcgc caccacgcgc agggcgatgg
    31381 cggttccaac ctgatagatg ctcagcgacg attcactact atgtacaatt tggcctgatg
    31441 ggagttggat cgtgtagaca ttctccgaac ctttgaattg ccgtgcaagg atacgggcat
    31501 cggctccttt agtcgggacg atgtggatat cgtcggggcg aatcatcaca acaacatgcg
    31561 tgcccgtcgc gaggtgttga gtattcggaa agtcgccgag ttctgtcgtc accaagtggt
    31621 gcgtcacgac tccggcgata aaatccgcct ggccgacaaa atcggcaacg aagggggtgg
    31681 tcgggaggtg ataaatggct tcgggcgtat cgaattgttc caggcgcccc ttatttaaga
    31741 ccgccacacg gtcagccatg gaaaatgcct catcgtgatc atgcgtgacg agaatggccg
    31801 tggtcttggt ttgtctcagc agggcgtgaa gatcctggcg catgcgactc gccatatcgg
    31861 gatcgagatt gctgaatggc tcgtcgagaa ggagcagcac cggacgaagg gcaagggccc
    31921 gggcgagggc gacgcgttgc tgttgaccgc cggacagttc atgcggatac cggtgctcca
    31981 atccacgcag cccggttaac gtgagtaggt cgtcgacgat tgcctgctgc tcggttcgtg
    32041 gaaggtgtcg caggccgaat gcaatgttct tttcgacccg taaatgggga aacagggcgt
    32101 attcctggaa caccatgccg atatgccgct gctccgtcgg aatcatggta tccggcgagg
    32161 agacccgttg accggacagc gcaatagtac ccctggtcac ccgctcaaat ccggcgatgg
    32221 cgcgaagaat agtcgttttg ccgcagccgg aaggcccgag gaggcagaga atctcccctt
    32281 ggtggaccgt gaaggtgatg ccctcgatgg ccggtcgtgt gggctcatag gcgcacgata
    32341 cgtcgcgcaa ttcaaggacg gccgatcgtt cgacggtcgt gtccagagta ttcgggatta
    32401 ttccctcgga tgcgggctgt tgccggcctg ttatagattc gttcacgagg ctcacgtgac
    32461 gcccttctgc gcctctccac gccagtcttt ggaaaccagc agcatcagcg ctggaaggct
    32521 caagatgacg atgagcaatg cggcaggcgc cgccagttgg taatactctt cgctggcttc
    32581 cagccacacg cggatggcca gtgtatcaaa tcctacaggt cgcaacagca atgtggccgg
    32641 cagttctttc atggtctgaa gaaacatcaa cacccatgcg gccacaaatc cattgcggac
    32701 gagcggaagc gtgactcgcc acaggctttg gtgagtcgtg catcccaggg tgcgggcgac
    32761 ttcctcgaca ttgggtgtca cttgttgcag ggccggttcc atggattgga ggccaaccgg
    32821 aaggaaatgc agaatatagg cgatgatgag cacgaccaca gtcccataca atgccggtgc
    32881 gaagtgggta aaaagtacga gaactgccag tgcggctacc ggtcccggca gcgcatagcc
    32941 ggcataggcg gcttgaaggc aggcaatgtt cagtcgtgag gggcggcggc tcgcgaggta
    33001 ggctaacgga aggccgatga tgaccgcgcc gcaggctgcc agtgctgcca ggaaactgct
    33061 gttccaaata aagcccagaa agcgcgtgtc caacgcgcct tgagaaatgg cttccacgct
    33121 ccattggatc aacatggctg ccggaatgcc aaacgcggct ccgaagacca ggacaacgta
    33181 gctggtgatg agcgctgttc cgagtggccc tgcatgttga cgtgtcgatc gtcggtatcg
    33241 acccgatgtc tgatagaagc gactgcgttg gcgaaaccat cgttcggtca ccaggaagat
    33301 gatggccatc acgacgagca gtaggctcaa aatactggcg gccgtgtggt catatcggct
    33361 ggtcatctgt tggtagaccg cataggtcag ggtttggtac cggagtaagg acaccgcacc
    33421 gaagtctgag atcacataca ggatgacgag tgccaacccc gctgcaatgg ccgggcgaat
    33481 aagcgggagc gtgacccgcc gaagcgtagc ccatggagag acgccgcagg cgcgcgcgac
    33541 ttcttcaaac gagacattga gattttggat tgcgctgcgg accagcaggt acacgaaggg
    33601 aaaggtgtcg agggccatga tcatggtgac cccgggaaaa ctttggggcg agggcaggcg
    33661 agcctcatgg ccgaagagca gttgccacca ctgttctgtc gggccgccca ttcccagtag
    33721 gtgggcatag acgtacgcca gcacgtaggt gggcatagcg agaggcagcg caagggccca
    33781 ttcccatatg cggcgaccgg ggaagtcgta tcgaacggtg atccaggcca gcgatacgcc
    33841 taacaccaac gtaatcagcg cgacgccaag ggctaacgac agcgtgttcc ctaagagttc
    33901 tggaatgcgc gtggaccaga ggcgagccca tacggccggt gcggccgtca tcgcgacata
    33961 gacaatgtac gcagtgggca ggaccaggaa cgctgcagtg aagagactga tccactgcag
    34021 ggaagatggc gcccgaactc tggtcgcagt aagcatgctc ggccacaggg gtcagcgaag
    34081 gccgacctgc tcgatcaggg tgagagtgga ttcgcgcaat tcagcgagtc gggctagagg
    34141 aacgagtgcc gcgcggaagc tatgccggtc gacgagagcc gggtcggctt ttacgtccgg
    34201 gtgcagtgga tattctttat ccaagtccgc aaagagtttt tgccccgcct gggccaccag
    34261 aaactcgatt aatagtttgg cgctgtcgac gtgtttcgag gctcgggtca ctccgatgcc
    34321 ggtcacattc atgatggccc ccatgccgcc ttcctgctga tcggtcatga tcgcggcgat
    34381 gggcgcggtc ggctgtgctg ccagatgacg ataaatatag tagtgattga cgatgccggc
    34441 tgcgacctgg ccctttgcga ctgcttccac aatttgtgaa cttttctggt agacctgcga
    34501 ccccgcattg gtcttcaggc cttggagaaa ttgtttggtg cgttcgtccc cgaaggtggt
    34561 cttaatgacg gacacgccgg cttgaaggta ctcgctgccg gaattcggga tggcaatttt
    34621 gtctttccat tgtggctggg ccaggtcgag cagcgacttg atttgctcgg gtttcaccag
    34681 agtcgtgtta tagacgacca cccaaaatcg gccggaaagc ccgatccagc tgttgtccga
    34741 agcgcggaat tgagagggaa tggcccgctc gacttcacgc atgttcatgg gacgaagaag
    34801 tttgagttct cgcgcatgtt cgaggcttcc ggcatcgttg gtcagaaaga catcggcagg
    34861 ggtgtggtcc ccctctgcct gcaaccggtt gaccaactcg gtggttcctg aggacaggag
    34921 ttcgatctga atgccgcttt tggtttggaa ttcgtcaaga accggcttga tcaatcgctc
    34981 agcacgacca gagtaaacga cgagtttgtc ggctgcatcc gcggtcttgg caggccactc
    35041 ctggagtatc aacgccgaga tgagcagggt cagagcaaat acggtgcgag ggaatgaagc
    35101 catgcggcgt gcctccacga gtgaggacgc tcggggcgtc ctagttgaaa ttgataagcc
    35161 gtctcaagat gataccggat gtgaagagaa tccgtcaatg gcggcagcgc gcgcagaggc
    35221 cgtacagttc tagtcgatgg gtttgaatga caaacccatt ctttgtggcg acttcctctt
    35281 ggagtcgttc gatttcgcaa ttctcaaact ccacaatggt gccgcaaccg gtgcagatca
    35341 gatgatcgtg atgacctttg tgagagatgt tgtcgtattg tgtctgggta ccgaagtgtc
    35401 gagcctgggc aatgccagcc tcgcaaaaca ggttcagtgt gcgatagatg gtggcgaggc
    35461 caagatgcgg gtccttcttc gcgagctgat ggtacatggt ttcagccgtg acgtgttcct
    35521 gtcgtagaaa cgcggtcagg atcagttcgc gttggcgagt cagctttaat tggtgcttgg
    35581 ccagatgctg gcgaagcaca tccatctctt taagattttt gctcatggtg tgtgactcgg
    35641 cgtgaaagag gctcattaaa aacgaaagtg cctcgatcgg tcaagagggg acgcgcagta
    35701 ggccattgtc gattgacgaa tcggaagcgg cctgtttata gtcccccgtc accgccaatt
    35761 gtgaggagat tcgacccttg cgcaaatccc acgaaatgac cgttgatcgg gccctgctgc
    35821 tctatgtgct ttcgctggct gagccctatg ggttgttgag cgacgtgaag cttcagcagc
    35881 tctgtttcct ttgtgagctt cagatgttcg gaaaggggct caagggtttt cactttgagt
    35941 tcgtccggtt cgcgtatggc gcgttcagtc gggatttgga caatgacctg acctcgctcc
    36001 ggcgcaagga acgggtcgaa aacttcagtc cctcagatca ggttcgtgat gagacgctcc
    36061 cgctcctgct gaaagggatt gacggaaatg aaacgaatga aaaggtgcgc gacctcatgc
    36121 aagcggtcat tgccacctac gggccgcagg atgtcactgc tattatgcag tcagtcgaat
    36181 cggtggaatt gagtactcca cagcagcccg atttcaaaat tcccatccgc gatatcgtct
    36241 ttcataccac actcctggtg ccgtcccgaa ttgaagcgcc agcagaattt ctcttgcccg
    36301 ccaatcatct ggcgaagctc aatgtctcga tgggatactg agctcgattt cttgagccca
    36361 cacctgcttg atagttggaa ttgctcacaa ggctggcagc aggcctagag atctctctta
    36421 acaaggagga tattcccgct catcttccat taccagcgtt gctggtacat ggttttagtg
    36481 gcgccggggt aaggtgagag ccgactgtat cgtatgcagc atggctcccg tttcgatggg
    36541 ttccagcaaa caatactcga tttgtaactc ccggaccacc cgctgaaact tctccccctc
    36601 cagggcaggt tcgtgcagag ccgctgtaac aactattctg gagcttggaa aggcttttcg
    36661 taggtcgacc agatcttccg gcccctggtc atcgtcggcg acaaggcggg cgacgacgag
    36721 atccagctta gatgcgggcg gttgagcaga ggcattgtgt aacgtggcac tatactgaac
    36781 gaagtgctcc attccaggca gcgccaactt gatgagccgt ttcagattcg agtcggcgtt
    36841 gataatcagg atattggcca taatcccccg acgcgaagtg atggtggaca gcgattgatc
    36901 atcgtgcgat cactcaaaaa aacgtcgcag atgtctgccc gttttggcgg agatggtgtg
    36961 gtgaaggtgt gcctcctctc gataacctcg tggggttaaa ccagttgctg atccagggca
    37021 taccgaatta actctgcggt cgttttcatt cccaatttcg tgagcaaccg ggcccgatag
    37081 gtgctcacgg ttttaatgct caggttgagg tgttcagcaa tctcggtcag gcgccggcct
    37141 tgcgcaatcc actggaggac ctcaatctcg cggtctgata ggactgcagg caggtcgtgg
    37201 gcgcacggtg tgttgcggtc cagcatcgtg tcggagacct gttccgattg cggcgggggg
    37261 aaatagttcc cgccttgcag aattcgggac acggcagcac gaagttgttg cggacccgtg
    37321 tctttggtca agtatcccag tgcacctgct cgaatggctc gagcggcata gtgttgctcg
    37381 gcgtatatgc tcacgatcag aatcggcaga ctgggttgaa gagatttcac aatgcgcaag
    37441 acttccaatc caggcatgtc tggtaagttc aggtcgagaa tcaccagatc ccaagctccc
    37501 gtccgaattt ggtcaatcgc gctatgggcc gagtcggttt cggtgatgtg aggcgttaat
    37561 ccatcttcgg tgagaaaatc ctgcaggaat tccttgaggc cgcgccgaag gagggcatgg
    37621 tcatcggcga gcaagatatt gagttctgtt ttgacggcgg gaagggtgtc aaatgcattc
    37681 acagcagtga attcccccta tggtgtggtg ctgagcatgg ggggcgccgt gcggaaacga
    37741 aggtccctcc tggcccgcct gccattccaa tacggagcag aaatgagctc tgccggcgtg
    37801 gaaacaggcg gaaagagagc gttcatgccc cttcatgacg tctagtcgtg gcggcgttcc
    37861 agcggacatc gaccctcagg ctacagccgg gacttctccg gcgcaaattg gctggctgag
    37921 acttccttcg attccttggc ccacgtgctc agtcgattca atctcaggga aagctctaaa
    37981 aattcctaga tttaagtagg ggaaaagtat cacgcgtaag gggcgggcgc cagagctaaa
    38041 gggccctgtt atggccctag agaattctcg cgactccagt atgcttgtat tcccgaacga
    38101 gcccgcgtgg cactcatctg cagagagacg ggaagagact gctggggagg attacaggcg
    38161 gtaaagggct ccgtatttcg cctccagata ccgtaagaac ggttctggcg tcacgccgtt
    38221 ccccgtgaca cgtcgagcta aatggtccgg cgtaaacata cgcccccacc ggtgaatctt
    38281 ttgttccagc cagtgccgaa gcggcaccaa ctgcccggcg gcgatctgtt cttccaattg
    38341 cgggagctcc agctttgctt gttcgaagaa ttgcaccgag tagaggttgc ccaaggtgta
    38401 ggtgggaaaa tacccgaagg ctcccatcga ccaatggacg tcctgaagga cgccgtcggc
    38461 gtcctgtgcc ggcgtgatcc ccaggtaggc ctccattctg tcattccaca ggcttggcag
    38521 gtcttccgga tgcgcccgtc tttcaatgag cgcctgctca atttccacgc gcagcatgat
    38581 gtgcagattg taggtcagct catcggcttc tacgcggatg agcgaggggg tgacgcggtt
    38641 aatcgcggca tagaattgat cgagaggcac cccggccaat tgctgcggaa atgtgtgctg
    38701 caaaatgggg taaaagcatt gccagaaggc tcgcgaccgg cccacgcagt tctcccagag
    38761 ccgcgattgg ctttcgtgaa aaccgagcga gacagactcg ccgagcggcg atccgtaata
    38821 gcgcgggtcc aggccctgat cgtacaagcc atggccgcct tcgtggatgc agctgaacag
    38881 gcatgacggc aaatccttct cgaagacccg cgtcgtcacg cggacatccg tcgggtgaaa
    38941 tgaggttgta aacggatggg ccgagagatc aaggcggcca cgctcgaagt catatcccat
    39001 ggcgacaagg acgagtcgcc cgaactcgat ctgcttcgtg tgatcaaagc tatggtgaag
    39061 gcaggtgtcg tcgatgcgca ccttgctggc ctgaactcgt ttcaggagcg ggaccagccg
    39121 cgcccgaagt tgtgcgaaga gcggcgtgag ttggcccact gtggcgcctg gctcataggt
    39181 atccagtagc gcgtcatagg gtgagtcccg gtatcccaag tactgagtct cttcacattt
    39241 gagatcgagg atggttctta acgaaggaag gaacttcgag aattgacttt ctgctcgtgc
    39301 cgtcacccag gcctgttgcg ccaacgaaca ttcacggctc agacggatga caaaatcaga
    39361 cgggagcttt ctcgcacgac tgaaatcacg ccaggtttcc cgcaagagcg atcgcgacgg
    39421 ttcatcccag tgttctgccg cttgcccggt ggaagggtcg atccactcat tcaataggga
    39481 ttcaatgtga ggtgacacaa gccgctcatg cgccagaccc tccagcgtgg caatttgttc
    39541 ggcgcgagct gccccgccac cagccggcat gtatgtttcc tgatcccacg acagaacaga
    39601 agctgcgctt tgaatccggc ggatttccag cagtcggttc gttaacggtt ccaaggtctt
    39661 caaggtcttc acttgtgcgc tctttctcca cgatgtccgt ggtatgattc gcggccggtg
    39721 cgaattgtcg cacaactgtc tcctggagtg aaactgatgg ccgatctcgt gtcgccgaat
    39781 atcgatgcct atgctgctgc ctgttctctc ccggaaacgc cggttcgtcg ggcgctccgt
    39841 gaggaaactg aacgtacaat ggagtacgcc cggatgttgg tgggcccgct ggaaggggcg
    39901 tttctgcatg tgatgacgcg cctggtgcga gctgagcggg tcctggaaat cgggatgttc
    39961 acgggctaca gcgctctctg ctttgccgaa gcattgcccg atcagggtcg ggtgatcaca
    40021 tgtgaggtgg atgaggactc tgctgcggta gcgcgtcgat tctttgcgca gtcgccgcat
    40081 ggccgtcgaa ttgagattcg tatggggccg gcactcgaga ccatggcaga attgacggga
    40141 cccttcgatc tgatttttat cgatgccgac aagctgaact atgtgaacta ttaccggcga
    40201 gcgatggaat tgctgtcgcc gcgcggggtc atcctggtcg acaatgtgtt gtgggggggg
    40261 gatgtcctca ccgatccgcc gccggatgac cggactgcgg caatccagga cctcaaccgg
    40321 atcgtggcgg ctgatccgcg tgtcacggcc gttctcgcga ccattcgcga cgggatctgg
    40381 gtcatcactc acaaatcgtc gcactagcat cactggtcga gacgttccga tcgaccactc
    40441 gatataaatc ccaggaatcg cttgaatgga aaaaccgtcc gcatccgccg cctatgcggc
    40501 attgacgatt tcggccttgg tctggggtgg ttcaatcgtc gggcaaaagc tggctcttgg
    40561 tgcgttttca gccgtagaga cgtctctcat ccgcggcatc ggcgcgctgg cgatcttaat
    40621 cccgttgtgg tggtggactg aaggtaaccg tacaacttta acggcccgcg acctcaaagt
    40681 cctctcttta ttggggttgt tcgtattcgg taaccatctg ttgaccctgt tcggccttcg
    40741 ctatatcgga gcctcaacgg ctggggttct gatcggcgcc agtccggcca ttacagcgct
    40801 tctgtcttcc ctcttggtgc gtgatattcc attcaaccag gtcgcaggcg gctgcgcggt
    40861 ctcctttgct ggcgtcgcgc tcgtttcggg agtcggaggg gatgctccca tcggcgatca
    40921 tccctggtta ggtgggacgt tagtattgtt ggggctggtg agctgggcgc tgtattccat
    40981 cgggggccgt caggtgatga accgattgtc tccactgacc gtcaactgga ccacgctgct
    41041 gctctcgctg ttgttgcaga ttcctctcct ctcgaccgat cagaaaatgt tggtgaccgg
    41101 tacaagcgct gtgccggttt ccggttggct ggccgtgggg tatctcattg tgttcgccac
    41161 ggcgttgggc caacaggcat ggttatatgg cgttcaaggc gtaggacctt cgcgggcagg
    41221 ggtgttcgtg aatctcattc ccgtatcggc attgttgctc tccgccgtga ttttgggtga
    41281 agcaatcggg gcacgggaaa ttgcgggcat tgtcctcatt ctgatgggcg tgtggttggt
    41341 cggccgacaa accgagccct caaaacgtcg tggctagctc ggtgcgctgc tcgttggtgt
    41401 catcgatcca gccgttctgc tctgacgctc ttttcgttcc ggctgtcgct tgaatgctcg
    41461 ctctgtagta tgattgccgc caggttggca cctccacgat cgctggaacg ttggcagcca
    41521 gcccatcatt ctcctctcag tcttatcggg atgggtcccc acgggaagcc acatgattga
    41581 acatcatgat accggcttaa gcagagtgct cgtcatctcg actcggccgg acggaatcat
    41641 taccagtttc aatagcgcgg ccgagcgatt actcggagtc ggcgccgatg cggttgtcgg
    41701 taaagtgacg ccggctgcct ttcatgatcc ggatgagcta cgccgccgca gagaagccct
    41761 tgcggccggc ttaggaaagc caattcaaga ttcgttcggt gtcctcgttg cccgggtcgc
    41821 tattggacgg atgaccgaag acgagtggac gtatcttgat cggagcggat atcggtttcc
    41881 ggtatttctc tccgtgagtg ccattcctga tgaagctgga cacgttctgg ggtactgctt
    41941 tgtcgccaag gatcgacgcg ggcaactgca agccgaggca ctgcttcgtc gtcaggcaaa
    42001 actgctcgac ttggccaacg atgccattct ggttcgcgat ctgcaagccg atacgattac
    42061 gtattggaat gaaggcgccg tgcgattgta tggatggacg gctgaagaag cgctgggggc
    42121 gtatatccat gactttttga gcaccacctt tcctcttccg ttagaggaga tcaaacagca
    42181 atttctggag caggggctgt ggcgcggtga actcgtgcat aagacacgtg ccgggaggga
    42241 gattaccgtc tccagtcggt ggacgctgtt gcgcgatgct gctgggatgc cgagcggcag
    42301 tctggaattg aacacggata tcacggagca aaaacgggca cagaaagcct tgaaggatgc
    42361 gcatgaagaa ttggaattgc gggtcatgga gcgtacaacc gacctccgtg atgctaatga
    42421 gcggctacgg atcctttcgc gccgtctcat ggagattcag gaattggagc gccgggcgat
    42481 cgcccgcgat ctgcacgacg agatcggtca agcgttgacg gccattaagt tgaatcttcg
    42541 ggagcttcga acccatccca attgcgagcc tgtcgaggat cagatcgcag acagtttgga
    42601 aatattggct caggtgctgc agcgggtgcg tagtttggcg ttggatctac ggccatcttt
    42661 gctggatgaa ttgggtttgg tgccggctct cagatggtac gtcggcagac aggccgaacg
    42721 cgcgggctgg cagttgacgt tttctgcaga cggcctgacc agcaggccgc ctgcggaaat
    42781 tgaaattgcc tgcttccggc ttgcgcaaga agcgttgacg aatgtcgtgc gtcattccca
    42841 ggcgaagaag gtagaagtgc tgctggagcg ctcttcccaa gcgctgacga tggtgattcg
    42901 cgacaatgga atcgggtttg atcgggatga ggtccgatcc ggagccagcg tcggactctc
    42961 gggtatggaa gagcgggttc aacttgtcgg gggagcgttc agcattgaat caactccggc
    43021 cgtgggcacg gagattcgtg cgtactttcc gcatggtgtc gcgaccaaag gcactgagga
    43081 ttcattggta tgaacaaaat cagggtattg ctggctgagg atcatacatt ggtccgggcg
    43141 ggatttcggg ctctcctgga gaaactggaa ggaattcagg ttatcggtga agtgagcgat
    43201 ggtcgcgacg cactgcgggt tgctaaagag ctggatcccg aagtggtgtt gatggacatc
    43261 gccatgtccg gcatgaatgg tttggaggcg acgagtcgga tgcggcagga atgtccccgg
    43321 actaaagtgc tcatgctgac catgtacacg aatgaggagt acctcaagga agccttgcga
    43381 gctggcgcat cggggtacct gctcaaagat gcggatcgtc ccgaattaga gctggctatt
    43441 aagaccgtct gtcgaggcga gacttatttg actccggcta tggctaaatt caccctggat
    43501 gcctactgtc ggcaggatga tgtgccgatg agcccgctga gcaaactcac ggggcggcaa
    43561 cgtgaaatcc ttcaattgat tgccgagggg tgctcgacca aacagattgc ccaccgcctt
    43621 gatttgagcg tcaaaactgt ggaaacccat cgagcccaac tgatggaacg cctcgaaatc
    43681 cacgatgttc ccgggctagt gagattggcc ataaggacag gattggtgcg ttcagatacg
    43741 tgaggaataa caatctgtta gattgatttt gctgccgcgt ttgttccgtt tgcgatccgg
    43801 aataatttcg aggactcagg gaatccccta ttacaccccg ggatgtggtg tgccatatta
    43861 ccgctgcttc acgggggttc gttccttgaa tcatggctga acattcgcca taccaaattg
    43921 ggctgctggt ccttcctcat caggttattc tatgaaaaaa ttgcgcgtgg ctgtccttgg
    43981 cacaggggca tttgctgaag cgtgtcacgt gccaggattg caatcgcatc ccggcgcaga
    44041 ggtggtcgtc ttatgcgggc gaaactcggc gcgaactcga gccatggccg accgtctcgg
    44101 ggtgccggaa atttcgctcg actacgaaca ggtctgcgca cgaaatgata tcgatgcggt
    44161 aaccatcgca actccaaacg tggcgcatgc cctccaggca aaggctgcgt tttcagccgg
    44221 gaagcatgtc ttttgtgaaa agccgctcgg catgaatgtt caagaagtca ttgaaatggt
    44281 ccgagccgca gaacgtagcc atgccatcca ccaagtcgca tttacctacc ggtatttgta
    44341 tggtgttcaa gaattgaaat gtcggctgct taaaggcgac ataggcgaac cgtatcatgt
    44401 gcgtgtgca
//
LOCUS       DAOQPD010000023        43904 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_339_length_43904_cov_24.529408, whole genome shotgun sequence.
ACCESSION   DAOQPD010000023 DAOQPD010000000
VERSION     DAOQPD010000023.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 43904)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 43904)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43904
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_339_length_43904_cov_24.529408"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..365)
                     /locus_tag="PK063_07545"
     CDS             complement(<1..365)
                     /locus_tag="PK063_07545"
                     /inference="COORDINATES: protein motif:HMM:NF015147.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LEA type 2 family protein"
                     /protein_id="HMZ96939.1"
                     /translation="MNYVRVVAGLLTALMVSGCASWMMNGEPPEVLVTNVTPLEGSAF
                     ERRLQVDLRIRNPNDFDLAVTGIDFKLDLNGNRLARGLGNKELVVPRLSDAVTSVETS
                     TSTLQVVRQLLSFSGNQPLT"
     gene            504..1124
                     /gene="msrA"
                     /locus_tag="PK063_07550"
     CDS             504..1124
                     /gene="msrA"
                     /locus_tag="PK063_07550"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HMZ96940.1"
                     /translation="MRSIIGRFGALGVLPMVLAGLLVSQSQAADPSGAAKAYFAGGCF
                     WCMEEVFEKVPGVTAVVSGYMGGRVEHPSYEQVSAGGTGHAESVEVVYDPTKASYTTL
                     LDAFWHNVDPVTPNAQFCDHGSQYRSVIFYQGEEQKRLAEESKRAIEQSQRLTQPIVT
                     ELTKASQFYPAEEYHQDFYKKNPIRYKFYKFNCGRAQRLEEVWGAP"
     gene            1163..1540
                     /locus_tag="PK063_07555"
     CDS             1163..1540
                     /locus_tag="PK063_07555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HMZ96941.1"
                     /translation="MRDCRTIAVVGLSSNPARPSYRVASYMQQQGKVVIPVNPRETDV
                     LGERAYPSLSDVPGSIDLVNVFRRSEEAGAVVDEAIRIQAKAVWLQEGVVDEAAALRA
                     RQAGLQVVMDRCWLKEYVRCVGE"
     gene            1756..2142
                     /locus_tag="PK063_07560"
     CDS             1756..2142
                     /locus_tag="PK063_07560"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96942.1"
                     /translation="MMRLLADCRSLMLVLPLMVTATGCAESALQGHSPQEDLGMGIVS
                     GTLGAQSRSAVSSGEQSTASVVGQVQAVEGGAYLVRDVRGQEHRIPHDENTRIDRPAH
                     VGDRIQSWFDRHGRAVLIRSLDEEGR"
     gene            2210..2791
                     /locus_tag="PK063_07565"
     CDS             2210..2791
                     /locus_tag="PK063_07565"
                     /inference="COORDINATES: protein motif:HMM:NF013618.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HMZ96943.1"
                     /translation="MARALFPLAVAGCLMALMPPASRLAFDPIMKEVAGRPTAEPIAS
                     LIATYAEQYALDPALLQAVIKVESNFNSDAVSSKGAIGLMQLMPLTAAAFHVLDPFDP
                     KDNIRAGAALLRGLLDRFGGDLSLALAAYHLGEARVRQAIGVPALPATQLYVNRVLGH
                     YDRFRAGTSRLPTRVTTRREERRTLWSLQQAPE"
     gene            2952..4106
                     /locus_tag="PK063_07570"
     CDS             2952..4106
                     /locus_tag="PK063_07570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HMZ96944.1"
                     /translation="MKKSDRTARLAQSDIRAMTLACAKVNGINMSQGVCDTPVPPVVV
                     QGAQQAMSQGHNIYARFDGIAELRQAIADKVASFNRITADPETNVTVSAGATGSFQAT
                     CMALLNPGDEVILFEPFYAYHVQAILAVEGVPRYVTMRPPDWTMDVKSLEQAVTSKTK
                     AIVVNTPGNPSGKVFTRRELEQIAEIACRRDLSVITDEIYEYFVFDGREHVSMASLPG
                     MADRTITIGGYSKTFSITGWRIGYSVAEASWAKAIGAMSDVLYVCAPTPLQYGVAAGI
                     RALGPSYYKELALDHQRKRDRFCGALAKAGLPPAVPQGAYYVLADVSRLPGNTSRERA
                     MYLLDKTGVAGVPGEAFFEGTEGSRFMRFCMAKTDADLERASQAIERLTS"
     gene            complement(4130..5536)
                     /locus_tag="PK063_07575"
     CDS             complement(4130..5536)
                     /locus_tag="PK063_07575"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF025017.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HMZ96945.1"
                     /translation="MWVDTLISTSEWLFLLYFLGLTAGYLMLDLIAIVHLRQYLQERV
                     LESLPHSYTGFEPQISILVPAYNEAATIAGSIRSLLQLSYSEYEIVVINDGSKDATID
                     VLRKEFDLFPFPEACNTQLPTAEIRGIYHSSSHTNLRVIDKENGGKADSLNAGINLSI
                     YPLFCCIDADSILQPDSLRRAVQPFLDDHRTVASGGTVRIANGCRVENGFLTKIGLPS
                     NLLALFQIVEYLRAFLFGRLGWSPLNAMLIISGAFGIFRKEAVVTVGGYRSDTIGEDM
                     ELVVRLHRHLRMGDKPYRITFVPDSVCWTEAPEDLRTLKNQRIRWQRGLCESLTKNLD
                     LLCHPKGGTIGWLAFPFMAVFEWIGPAIEVFGYCFLIFSFVMGFVSIQAWLILLVAAI
                     GLGVLLSVSALLLEEMSFHVYPDQRDVLKLLLAAILENFGFRQLNSLWKLIGLYRWVC
                     GKKATWGTMTRTASWQAR"
     gene            5517..7193
                     /locus_tag="PK063_07580"
     CDS             5517..7193
                     /locus_tag="PK063_07580"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96946.1"
                     /translation="MSVSTHIDQCVSARDGVARDQIDGKSVGRGTEAVGRRLFATVLC
                     SAAVISILWLSLAQAEDIPLSSPIPSTIHEIELTYAGNSTDPAVAFSGPVPPAGPLPY
                     RPFLPILELLPGFGVAHVFGPCHGQAVRSDSHLELEWTAGDAGRCGQRIELRPAGRPM
                     DLMSYQMLRLRGRATGQVVVAIEDLAGHQREHNQSLATVTGTFDLTIPLKEIGRGVDL
                     RYVTALVVSAEGPRGRIEFEQLTVSQRNTVKKPPGGTGFWVWNYRAAIQEPQPLLATC
                     RRQACSRMLIQMPSLNDDEAIWEGYASLMAQVQEAGIDALALDGYPEAIQEPHLLADK
                     VQRLFHLVRGGAVSGIQLDIEPYLLPGFLDDDGQLRRYLGAIETVSEAIHGRAKLSMV
                     IPFWLATPTVGGRPLAYAVMDRADEVAVMSYRTDLEEVQDIAEDILRYGDVSEKPVWL
                     AVETTVLPLEEHVVLRRDLRPDRADALLDREHKRLRWKPISEADRLTGSGEWFRIHRR
                     FTVRPERLTFAGRSRVEVSQAISHMLDTTMHPSFAGVIIHDLDGFRALPE"
     gene            7227..9590
                     /locus_tag="PK063_07585"
     CDS             7227..9590
                     /locus_tag="PK063_07585"
                     /inference="COORDINATES: protein motif:HMM:TIGR04390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ96947.1"
                     /translation="MNDSFTWINQRTSIAGLLAVIAFAAAWFFAPATMIAAMAPELSP
                     RQTLQQARVLEDEKRYEEAIAAYRQYLQAKPDDDDVRASVAKLLSWQGQWDAAAAAYR
                     DLLTRHPLDHDIRVGLAQVLSWQKHYDLAREEYERVLHDEPDHVEALTGLGNVYLWSG
                     HQDQAIPYYERVVALTGDADVAARLQSLKAASRSPVVPVNPSGAADGNDSLTAHAAQT
                     LERGRRLETMRQYADAVTVYREELQLSPTNDEVRAALARVLSWQGVHPEATTLYREIL
                     ARHPQDQDIRVALGQVLSWQKQFEEAGRVYQDVLQSDPTHVEARRGLADVAHWQGHYA
                     EAVQRYEALVAETHDPELEAQLKTIRSEWRTTSPQVAEHPASTHDSQGTDERVIGAAV
                     EEATKFEVAKQYPEAERVYRDVLRRHPDNDDIRTALARVLSWQGAHAEATTLYREVLA
                     RHPEDQDIRLALAQVLSWQKQFDEAERLYGAVSQAEPTRIEARRGLAEVAHWRGDRSE
                     ALQRYEALLDDTHDPAIEQQIKAVKSELLVSPRAAVGQGLAGLRLPYRDYAKIGYGHY
                     TYTKNQPDERDLLFELAKPLGNQTLVMRVEPINRFGFHDTPMSAELYSPLWSRAWGYI
                     AGQATINPHFSPNYSFVGEVAQGLGGLHSSLAPFEASFGYRRLNYKHDDIDLLMPGLT
                     IFLPFNLWLTEKVYFIPNTGAVTLASQLTWRPADRLQFFASGSFGTSGERIVAAQDFT
                     RVGSRTIQGGVTFPINERFSAETSGYYEDRGFLYVRRGGNFNLIYHW"
     gene            9595..11550
                     /locus_tag="PK063_07590"
     CDS             9595..11550
                     /locus_tag="PK063_07590"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96948.1"
                     /translation="MQRSTLVRVSGIALLFVSLVIGVRILVSAPPVQHMEVPEKDFHR
                     FQGVAGPDDATVVPRHVPTAWTTYEPGSTSRLAILLTDPDSSWLGLAHGLKSIGIPFR
                     MTRNVHEALAHKVVLVYPMISGKVLKPEELQALAEFPKTGGTLIGVQVLGGGLNHVFG
                     FRDAVASRQRYDMTLATADPLLADLTDPREQRLRVGIRDKGIEVMGTYGYTDASAPLA
                     RFDDGTAAVTQVAHGPGRAYAIGVDLGFLLLKGYNNRGEELVKTFDNEFDPTLDVWLR
                     LIKAMYRTAQEEAVTLGTVPFGKSLSVMMTHDVDFTQSIKHAVEYAEYEKRQGVVGTY
                     FIQVKYIRDYNDDIFFNDEGVRYVKQLADLGMELGSHTIAHSRVFNQFPMGSGRESYP
                     SYAPFVKDRTTAYNVSILGELRVSKFLIDHFSGQSIVSFRPGELSNPFGLPQALLATG
                     YRYSSTATANNSLTHLPYQLNYDRLTDSEVEIFEFPVTIEDEALPKMGDRLPQALEVA
                     KRISRYGGSVVVLIHPNVLDHKLAFEKGFVEGVRTYAWFGSVGEFGRWWAARNRVEVD
                     VVRDADAMRVTLNVPVSLAGLTLEVPPGWEVARSGNPLRGVAQHGTMVTFPQLQGTYT
                     VLFTPSSLTPSASRTSSSRSNTVNMGL"
     gene            complement(11578..12669)
                     /locus_tag="PK063_07595"
     CDS             complement(11578..12669)
                     /locus_tag="PK063_07595"
                     /inference="COORDINATES: protein motif:HMM:NF025030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HMZ96949.1"
                     /translation="MLGLDQSDLTLRIGTIAAISIYSSVLLLLLGILLLRYIRNNKDR
                     RRRAVTEIWRPILAECVVEVPETLPPLTTRDHLVLLYLWNHCYESIRGDARENLKELA
                     RRTGTDRFAKELLHARLLRRRLLAIVTLGHLQERSIWNELAAALQADNAFVSLVAAKA
                     LLHIDAKAAVPLIIPVISQRKDWSPLKVVAIFEPAGADIAAEAIAKAACLASPEIGSR
                     LIRHLAATQSQHALPPLRDMLQKGTPSDDLLAACLFLFGECSDPRDIVTIRTHLSHPT
                     WYVRLQAASALGKVGIEEDEARLIALLDDEHWWVRYRAAEALSNLPWMTTERLTRVHN
                     TLTTVESQEHLVPFMAQSNAKAQHPARIA"
     gene            complement(12691..13086)
                     /locus_tag="PK063_07600"
     CDS             complement(12691..13086)
                     /locus_tag="PK063_07600"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ96950.1"
                     /translation="MDNPETPKLRVLMVEDEEDTASLLKFLLERANYQVVHAKDGRQA
                     QELVNTIAPPDIVLLDVMLPFLSGLQVLTVIRKREGWKKVPIVMLTADGSEHDIKRAL
                     ESGANDYMIKPFNPRELTSRLKRFVAHAA"
     gene            complement(13295..13630)
                     /locus_tag="PK063_07605"
     CDS             complement(13295..13630)
                     /locus_tag="PK063_07605"
                     /inference="COORDINATES: protein motif:HMM:NF013767.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009927 - histidine phosphotransfer kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hpt domain-containing protein"
                     /protein_id="HMZ96951.1"
                     /translation="MSDMAPVTSSCGAGPIVVLVDSAFEPLIPKFMANRNKELATMTE
                     ALATSDFATIRQLAHGMKGVSGSYGFHAMTTIAGRMEEAAKVANGTSIRQDLLELASY
                     LTRVEITYE"
     gene            complement(13627..14085)
                     /locus_tag="PK063_07610"
     CDS             complement(13627..14085)
                     /locus_tag="PK063_07610"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ96952.1"
                     /translation="MPSSDNKHAGGEAQNPSHSSPLNILLVEDMEDNRVLVSLLLKAF
                     PYRLDLAEHGAAGVEKFQSGRYDLVLMDIQMPVMDGYAAIRLMRQWEKEQQRSETPIL
                     ALTGNTHDEDIGKAQAAGFTAHVMKPLKKVTLLEAIQRYAAPFSRKESAA"
     gene            14428..14913
                     /locus_tag="PK063_07615"
     CDS             14428..14913
                     /locus_tag="PK063_07615"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96953.1"
                     /translation="MNRMKQNQWFFLMMGLSLLSIQACSHAPRPQETTWTEPPAGEIS
                     LPRGEHAVLAGEWEYEEGGMVVPLRLDRFGNGSYDFKDGRFRTDLFSDHRWAGAWAQR
                     ENDREGGFEITLSPDYSEGEGRWWYTRIEGDKAPTKAGGRFHVMKVQSIVDNQPWPSA
                     R"
     gene            complement(14917..15825)
                     /locus_tag="PK063_07620"
     CDS             complement(14917..15825)
                     /locus_tag="PK063_07620"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF015411.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HMZ96954.1"
                     /translation="MAALATSERYSMNVALLGTGLLGQGVAERLHATGHDLTVYNRSI
                     KKTQALRQQGIRIALTAAEAMSAADVVLLLLSDAAAIRAVLFDPAASRAIDGRTIIQM
                     GTIGPAESCSLEKDVTGLGGRYLEAPVLGSIAEAKAGTLLVMVGATPEHYDKWAPLLR
                     YLGEEVRLIGPVGKAAVLKLALNQLIAAEMAAFAFSLGLIRRGGVDVNDFMGVVRKSA
                     LYAPMFEKKLSRLEKRNYAQPNFSTRHLLKDVELALSAAEKARLSPAGLQGVRSLLID
                     TIAAGLGDVDYSAIYEQIDPLGSEHG"
     gene            complement(15856..16659)
                     /locus_tag="PK063_07625"
     CDS             complement(15856..16659)
                     /locus_tag="PK063_07625"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: protein motif:HMM:NF012673.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'(2'),5'-bisphosphate nucleotidase CysQ"
                     /protein_id="HMZ96955.1"
                     /translation="MEYELTILSQAMSEAGREALRLASAGFETFTKADQSPVTSADLA
                     VNRILQDRLSTAFPEDGWLSEETTDNDTRLSRKRVWIVDPIDGTRSFVRGLPEFCLSV
                     ALVENGVPTVAAIFNPATGEFFSAIRGRGLRVERLSDSDQPGFTSSERPVALVNPWEL
                     RVGRFEGLQDHLHCRPIGSIAYALALVAAGQADAAITLAGGNEWDVAAGVLLVEESGG
                     RATTAAGHPVTFNRPDPRLPGTLAVGSDLPAPVRTRLIQHGLAAASHPL"
     gene            16801..17859
                     /gene="corA"
                     /locus_tag="PK063_07630"
     CDS             16801..17859
                     /gene="corA"
                     /locus_tag="PK063_07630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015087 - cobalt ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="HMZ96956.1"
                     /translation="MKLKHKHSRKAGLPPGTLVHIGEKRSETVTITVYEYGEGQYQER
                     TVSKPDEVVATGEPTVRWVDVGGIHKMEVLEAFGKMFGLHPLLLEDIANTDQRPKLDD
                     YGTYGYLVLKMLYEGQSEGDINVEQVSLVFGENFVLSFQENGGDVFQGVKERLRNGKG
                     RLRHAGADYLLYALMDSIVDRYFVILETLGEKIEALQDLCVTNPGPETLRDIHALKRQ
                     LLFFRRSVWPLRDVMNNLSRSDGQFLQGSTKVFFRDVYDHIIQIGDTIETLREMVSSM
                     MEVYLSSVSYRLNGVMKVLTIITTIFMPLSFIASIYGMNFEHMPELKSPWGYPAVLGV
                     MALTGLAMLYFFKQKKWL"
     gene            complement(17869..18258)
                     /locus_tag="PK063_07635"
     CDS             complement(17869..18258)
                     /locus_tag="PK063_07635"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96957.1"
                     /translation="MTWWETLLFPVAWLWRPKLLFTLLFFGGAAYLLIVFNWSYSDGD
                     RAGYLQKLSRKGWFCKTQEGELAMTTVPGVAPVLWSFTVWDENVAKKLDGQMGKRVVL
                     HYKEFRYIPTTCFGETPYFVDRVEVLD"
     gene            complement(18278..18898)
                     /gene="leuD"
                     /locus_tag="PK063_07640"
     CDS             complement(18278..18898)
                     /gene="leuD"
                     /locus_tag="PK063_07640"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HMZ96958.1"
                     /translation="MDAFTTLTGLVAPLDRLNVDTDQIIPKQFLKTIKRTGLREGLFY
                     DWRRRKDGSQDPEFFLNQPRYQQASILLTRDNFGCGSSREHAPWALLDQGFRCILAPS
                     FADIFYNNCFQNGILPVVLKAAEIQALFEGVAAHDGYTLTVDLAAQQVNTPKGMAYHF
                     DIDPFRKDCLYRGLDAIGLTLQHAAQIGEYEQRRRTQAPWLFQDVR"
     gene            complement(18977..20380)
                     /gene="leuC"
                     /locus_tag="PK063_07645"
     CDS             complement(18977..20380)
                     /gene="leuC"
                     /locus_tag="PK063_07645"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HMZ96959.1"
                     /translation="MAAQTLFEKIWNDHVVRAEPDGTTLLYIDRHLVHEVTSPQAFEG
                     LTVAGRTPRRSAAALAVPDHNVPTTDRRVAIADPVSAKQIQTLDDNCKTFGITLFGMN
                     DIRQGVVHVIGPEQGFTLPGMTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQCLV
                     QKRPKTMEVRVDGQLSPRCSAKDIILAIIGKIGTAGGTGYVIEYTGSAIRALSMEGRM
                     TLCNMSIEGGARAGMVAPDETTFNYIKGRPMAPKGTLWDQAVAAWRNLHTDAGAKYDA
                     VVELRAETIAPQVTWGTSPGMVTGVDGTVPDPRSMSDDKLRQATERAIEYMALKPGMP
                     IRDIKIDKVFIGSCTNSRIEDLRLAASFAKGKKVAGSVHAMVVPGSGLVKQQAEQEGL
                     DRIFKESGFEWREAGCSMCLAMNADVLQPGERCASTSNRNFEGRQGAGGRTHLVSPAM
                     AVAAAIEGHFVDIRQWS"
     gene            20542..20775
                     /locus_tag="PK063_07650"
     CDS             20542..20775
                     /locus_tag="PK063_07650"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96960.1"
                     /translation="MEQEPINADHISIPRWTIKRDPRALGCSICGSAIVKITAEWRQV
                     SFCTCRLIEYRVLPRAPKALPAPSPAADSRKDP"
     gene            20799..>21121
                     /locus_tag="PK063_07655"
     CDS             20799..>21121
                     /locus_tag="PK063_07655"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96961.1"
                     /translation="MARWQWALLAACCSVMLASGSALASDRAHAKSLTRSGLAVPASS
                     LRSCSGEDLLGTWSLVAFDSAYRFKDPQAPYLFPYQVFQYSGEQGAKSAHSRTPMLDS
                     PDRIL"
     assembly_gap    21122..21221
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <21222..21637
                     /locus_tag="PK063_07660"
     CDS             <21222..21637
                     /locus_tag="PK063_07660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MEKHLA domain-containing protein"
                     /protein_id="HMZ96962.1"
                     /translation="LDSYRHCVGRELMERVDGAEAQAQALFTAPIVVVSHGMQDDPIL
                     NYGSQLALTLWEMTWEQLVHMPSRLTAEPVNRTERESMLERARTQGYIDNYRGVRISS
                     SGRRFLIEQALVWNVVDRAGYRRGQAATFSRWTFL"
     gene            complement(21617..21835)
                     /locus_tag="PK063_07665"
     CDS             complement(21617..21835)
                     /locus_tag="PK063_07665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HMZ96963.1"
                     /translation="MIKPGRYRHYKGNDYEVLGVARHSETEEEYVVYRQLYGAGGLWI
                     RPMTMFSESVSIGGEIVPRFRRLEEGPA"
     gene            21885..23294
                     /locus_tag="PK063_07670"
     CDS             21885..23294
                     /locus_tag="PK063_07670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HMZ96964.1"
                     /translation="MPSQLSQKNERRHDVVVIGGGSAGYAAARTACEAGADVAIVDQG
                     PLGGLCILRGCMPTKTILRSAEIMALMKRAREFGLAPVTARADLSAIVDRKNRLVQEF
                     ADYRIAALRDPRFTLYESHAEFVSPHEICAGGLRIRGDAFVIATGSSVAKVAIPGLSE
                     AGYVTSDEMLDVRHAPVSLAVLGGGLVAVEFAQFFSRIGTKVTMLQRGATLLSDMDQD
                     VGQALASAFEDEGIEVLTGVAFDQVTSSPTGKTVHFRQNGVSHSRSAEVIFHALGRCP
                     NLKGLNLEAAGVKVIDGRLVVGADMRTSQPHIFAVGDVNDLTPIVHLAIQQGETAAFN
                     ATHPDVPARVIDHRLDSEMVFTDPQVAIAGLSERQCREQAIPYLTASYPFADHGKAMC
                     LGALAGFVKLLCRPDNGELIGAQIVGPEAAELIHELIAVMYFHGTAQDLLRIPHYHPT
                     LAEIVTYPAESILEQMGRI"
     gene            23291..23974
                     /locus_tag="PK063_07675"
     CDS             23291..23974
                     /locus_tag="PK063_07675"
                     /inference="COORDINATES: protein motif:HMM:NF037660.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ96965.1"
                     /translation="MRRPALVGLCALLLFMAWSCGQQTWEAAMQAGEVAVQRGQLGEA
                     EQIYAAALKKAEEFGPHDRRVAVTLAHLAQVYSTQGKFVEAEPVYLEALKIYQEVHGE
                     NHLDVAAMLNNLGVLHRKHGQFADAQRLLTRALAIKEKLLGPDHLEVALAVSNLAAMY
                     AAQGDTAQAAALFARALAIREKQLGPDHPDVAKSVIDYAGALRKIGRTPEADALEGRA
                     AAIRSKTKS"
     gene            24046..24261
                     /locus_tag="PK063_07680"
     CDS             24046..24261
                     /locus_tag="PK063_07680"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96966.1"
                     /translation="MSDLRTNALIARGMGIVFIAGGFMLGIYGLEFPNTMWLQTALGL
                     LVTGMMAQGYAMYCSIRWVREQRDSER"
     gene            24245..24736
                     /locus_tag="PK063_07685"
     CDS             24245..24736
                     /locus_tag="PK063_07685"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96967.1"
                     /translation="MTRNDNRLSYVSNRLLPLSVRWSRLGMLLCLAMLSGCGGPWRDT
                     YLNKGVHKLTQADIEDKFGPPSTAKTPVLGGDTVWTYRVPMGDREVHPWDPSSLAAGK
                     KTKAPPSPSPFGKSLAGNDEPYREPLYCYRYTLSFDEQKRLKDWKREECVPRTSEDGT
                     VVQ"
     gene            24754..25578
                     /locus_tag="PK063_07690"
     CDS             24754..25578
                     /locus_tag="PK063_07690"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96968.1"
                     /translation="MQDMLPVIGSSVFFDLLKSILLLLILLIARTVLVRWIKNNQALT
                     IDARRRWIVTTRNSMVLCLFVGLVVIWAHELEAFAVSLVALAATLVLATKELILCWSG
                     AALRVGGGVYGVGDRIQLGTYRGVVLEYDVFATKLLEIGPGQTSHLYTGRTVVFPNSL
                     LFGNPLIKESPSQEYGLYVLSVPLLSTDNWQAAEQALLGAAKVECAPFMDQMGRQMKL
                     LEQRNLLEAPSPEPRITIQLPEAGRIHLVLRFPAPDRGRSRVEQAILRRYLTTIRQ"
     gene            25772..26176
                     /locus_tag="PK063_07695"
     CDS             25772..26176
                     /locus_tag="PK063_07695"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96969.1"
                     /translation="MRRSIAVMVAAAFVGMSSFAAADDLGMGKMSEGMKQDMGTFSDE
                     MNAHKEELKSDLKAKKESAKSELKAKRDEAKAKKKQAKADAKAKKEHVKAKVKAKKDA
                     ARAKAADMKSAADDTVQEMGGMKNDLKEATRY"
     gene            26305..27078
                     /gene="xth"
                     /locus_tag="PK063_07700"
     CDS             26305..27078
                     /gene="xth"
                     /locus_tag="PK063_07700"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008853 - exodeoxyribonuclease III
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HMZ96970.1"
                     /translation="MKVATFNVNSLRKRLPIVLQWLERHQPDVLCLQETKVQDSEFPL
                     AALATSGYEITFRGMKAYNGVAVLSRTKPEFVCYGFDDGGEAEDARLLRVVIQGIPII
                     NTYVPQGFEIDSPKYQYKLGWYDRLLKHFDMHLSPKEPAIWCGDMNVAPRPIDVHSPE
                     KHLKHVCYHEDARKAYGKTIAWGFEDVFCKLYPDRQQFTFFDYRAPSALAANKGWRID
                     HILATAPLAQKCQRVDVDLEPRRATDASDHTVLWADFDM"
     gene            complement(27147..27326)
                     /locus_tag="PK063_07705"
     CDS             complement(27147..27326)
                     /locus_tag="PK063_07705"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96971.1"
                     /translation="MTCGRCKGLMVDEWRPDFSPETFVWRCINCGSIVDPLIEQNRRT
                     RMAEQLLLEPVEVLQ"
     gene            28002..28331
                     /locus_tag="PK063_07710"
     CDS             28002..28331
                     /locus_tag="PK063_07710"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ96972.1"
                     /translation="MIDRREHLRIPVRLFLSFSGGKVRGEGTVRDISMGGCIIESQAS
                     VHEDDIFYLQIVLENEQAPIEVAAMVRSVSSRGIAFKFLRSAQENKRLLAFVQSKTDS
                     VGPRSPA"
     gene            complement(28413..28718)
                     /locus_tag="PK063_07715"
     CDS             complement(28413..28718)
                     /locus_tag="PK063_07715"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96973.1"
                     /translation="MALDRSTDTPGGFQVRHRALGIFQGSSIGLAFWHPSSHMPEYGL
                     CRFATRAKAQDYVDFLSSPACPEPLSQADLIIEDFDHAEHERLTTEYPQASAWETPL"
     gene            28892..29482
                     /locus_tag="PK063_07720"
     CDS             28892..29482
                     /locus_tag="PK063_07720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HMZ96974.1"
                     /translation="MARLMGASFLLAGLLALSGCGYNDLQGLDEDTKATWSEVINQYQ
                     RRADLIPNLVNTVKGYAAHEKDTLEGVVQARAKATSVQITPELLKDEAAFKRFQEAQQ
                     SLSSALGRLLALAENYPNLKADQGFRDLQSQLEGTENRITVARKRYIDKVAEFNKMVR
                     YFPTNLTAKFLLHLDEKANFTVADEKAVAKPPEVKF"
     gene            29513..30418
                     /locus_tag="PK063_07725"
     CDS             29513..30418
                     /locus_tag="PK063_07725"
                     /inference="COORDINATES: protein motif:HMM:NF016424.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HMZ96975.1"
                     /translation="MRLMGRAGWAVLAGWLWFTLVPSLPARALDVPPLSGRVVDLAHV
                     LPPATTAQLSETLQAHESKTSNQVAVLIVPSLEDEPLFDFSHRVATTWKLGAKGTDNG
                     VLLLIAIKERKIRLEVGYGLEGVLTDARSAQIIRNEIAPKFRAGDVPAGVTAGVQAVL
                     HTIEGTYRAPESPTAVHSDGEVIGNTIVAVIVGVVIGLFFSRAHRVLGPVAGGGLSFL
                     VAPWVIPALIAGAASVALVSLMSGLGQASGGGRRSRSGPFDDTWFSTRHGGWGSGGLG
                     DSFGGSGGFSGGGGDFGGGGASGDW"
     gene            30405..31067
                     /locus_tag="PK063_07730"
     CDS             30405..31067
                     /locus_tag="PK063_07730"
                     /inference="COORDINATES: protein motif:HMM:NF016424.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HMZ96976.1"
                     /translation="MATGSKPALTEAERARVEAAVQAAEQHTSAEIVPLIVGRSGLYR
                     EAHHRAGLLSAVLALTVLVTIETAWLPWGWQASNAVWLVGITVLAYSVGVWVGTWPML
                     LRLFTSRDRMRHKVHMRAERAFAQQGLAQTRERTGLLLMVSLLERQVYILPDQALQGR
                     ISVDQWQDIVSVVVERMKVGDLAGGLCHGIEAAGVLLARACPSREGDNPNELPNAVIQ
                     DL"
     gene            31125..32753
                     /gene="murJ"
                     /locus_tag="PK063_07735"
     CDS             31125..32753
                     /gene="murJ"
                     /locus_tag="PK063_07735"
                     /inference="COORDINATES: protein motif:HMM:TIGR01695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0034204 - lipid translocation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HMZ96977.1"
                     /translation="MSDPAATPEPSQPAVDETHSVVKAAGLIGIATFSSRILGFVRDM
                     VLARLFGATPAADAFFVAYRVPNLLRELFAEGSMSAAFIPVFTEYHTLKAKRDAWELA
                     SATFTTLLTIVTAVTLVGILAAPGIVWLLAPGFRESVDKLALTTLLTQLMFPYLIFIS
                     LAALAMGILNSLRDFAAPAFSPVFFNIFTIACMLFLSPWLSEPILAVAIGIVVGGVAQ
                     FAMQLPGLKRRGMLFGLRFNPGHPGVKRIGLLMVPSLLGLSVTQINITVSTILASYFS
                     GGPTYLFYGMRLIQFPLGIFGVALATAILPTLSAQAARGALDELRTTIGFGLRMIFFI
                     ILPAMAGLILLRYPIVHLVFEHGSFTKTDTLATATALLCYAVGLWAFAGVRIIVSAFY
                     SLQDTRTPAITAGIAVGANIGLSLWLMTILDAAGLALATALASMLNGSILVAVLHRRL
                     GRVDWGAVVRSAGRVLAASIPMAGICLWVASAPLWMETGQWIVKSVMLFGGIGFSVIA
                     YLGMHLMLGSDELDVVMGLVKRKLGRVARKFGVA"
     gene            32899..33255
                     /locus_tag="PK063_07740"
     CDS             32899..33255
                     /locus_tag="PK063_07740"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: protein motif:HMM:TIGR00589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HMZ96978.1"
                     /translation="MKEAQAQLLSYLDGERREFALPIDWSAGTSFQRKVWKAIAGIPY
                     GRVRSYQWVAMRVGGKQYARAVGMALGANPVPIVVPCHRIIAHDGSLGGFSSGLPLKR
                     RLLGLEGTLTQLRNAR"
     gene            33282..33752
                     /gene="dtd"
                     /locus_tag="PK063_07745"
     CDS             33282..33752
                     /gene="dtd"
                     /locus_tag="PK063_07745"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HMZ96979.1"
                     /translation="MKAVIQRVTRASVEVEGQVVGRIDLGLLVLLGVAKGDGEGDLSY
                     LVEKVQALRIFNDDQGKMNRSLRDVGGALLVVSQFTLLGDTAKGHRPGFDLAAPPEAA
                     RAWYDEAVQRLRHEGLKVETGVFGAHMQVELLNDGPVTFIVDSRRPGAHADLKS"
     gene            33851..34417
                     /locus_tag="PK063_07750"
     CDS             33851..34417
                     /locus_tag="PK063_07750"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96980.1"
                     /translation="MGSPVSRSHPLRQLFGALTEKSFTEHLGWPDLNVTEYVSNLLVE
                     FAHTDQLYKIQNTQGRPLDSVVEMLFESEVLLEAQSFERERDVHRHIGDFTLFMTGLF
                     PEYLRRLKSVGRIYHKDFLVDYVKAGKRSYGLVAEFGHYDPEQDTPLFRKLSENFELC
                     VTGLGFVRSDLDRMQDPACRRVKDLLLN"
     gene            34414..35352
                     /locus_tag="PK063_07755"
     CDS             34414..35352
                     /locus_tag="PK063_07755"
                     /inference="COORDINATES: protein motif:HMM:NF013292.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoaspartyl peptidase/L-asparaginase family
                     protein"
                     /protein_id="HMZ96981.1"
                     /translation="MKRLRPVLLVHGGAGRRAMTVAQAACVERTLAEGHRLLQAGVPA
                     LSVVEEAIRLLEDSGLFNAGRGSNRQLDGVRRMDASIMEGRDLRAGAVASIEGILHPV
                     TAARLVMEKTAHVLLVGKSASRFADYFGLERAPRSRRSLTAQPKQLRPAAGVSRTLQL
                     HQAIVKTGRLRARSLGKETVGAVALDVKGTVAAGASTGGVDVMLPGRVGDTPLIGCGV
                     YADNDAGAVSMTGLGESIIRVAVAKEIADGLATGLSPVAAANRVLRKVVERVQGAAGV
                     LVLSPDGRCTIRHSTPHMIAGIIGPDGRAIVRDRFA"
     gene            35393..35821
                     /locus_tag="PK063_07760"
     CDS             35393..35821
                     /locus_tag="PK063_07760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HMZ96982.1"
                     /translation="MPALFHLAFPVHDLAAAKQFYVEGLGCVLGRESPTAVTFGLAGH
                     QLVAHLSEDELDRQKGIYPRHFGLVLTREEEWQALADRAEAQHLTFYQQPRRRFPGTR
                     IEHRTFFLEDPSGNLLEFKYYVHESAIFGERDYTSVGQST"
     gene            complement(35853..36629)
                     /gene="mtgA"
                     /locus_tag="PK063_07765"
     CDS             complement(35853..36629)
                     /gene="mtgA"
                     /locus_tag="PK063_07765"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: protein motif:HMM:TIGR02070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009274 - peptidoglycan-based cell wall
                     [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="monofunctional biosynthetic peptidoglycan
                     transglycosylase"
                     /protein_id="HMZ96983.1"
                     /translation="MSKSTGSLFGRILFWMTVLIGLPAAALALYWLATLPDVSRLAKH
                     HPTETAVMEARRAQAKEQGHPLHIKFAWVPLSRISPALQRAVVAAEDASFFAHEGFDW
                     EGIKDAALYNLEVGEFKRGGSTITQQLAKNLYLSSERSLLRKAREALITRSLEHHLTK
                     KQILELYLNVAEWGQGVFGAEAAARHHFGKSAEDLTIEEAALLAAILPSPRRYDPIRH
                     TAYLTRRQRHIVRWLERGNGRKAASINRLPPESLEVVPVE"
     gene            36659..37363
                     /gene="yihA"
                     /locus_tag="PK063_07770"
     CDS             36659..37363
                     /gene="yihA"
                     /locus_tag="PK063_07770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HMZ96984.1"
                     /translation="MAHLSSVAQVGAHPALLPDAIIMKLLSAEFIKSSVSPEQFPADH
                     LPEIAFVGRSNVGKSSLINSLLHRKKLAKVSKTPGKTRAVNFFTVRTSDPKLPLLSLV
                     DLPGYGYAKVSKTMRAQWGPMIEQYLEQRQSLGAVILLIESRVWMPQDVMTIQWVQSL
                     GCGLIIVLTKADKLRQSERKPTLTEVRVACGLPAEVPVLLYSAETHEGRDALWGEIRA
                     QFNGLQKHESGTRELR"
     gene            complement(37522..38481)
                     /locus_tag="PK063_07775"
     CDS             complement(37522..38481)
                     /locus_tag="PK063_07775"
                     /inference="COORDINATES: protein motif:HMM:NF024545.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HMZ96985.1"
                     /translation="MRPTSLQSLSRPALAGLCLYVWVGLFPAGPVDAAKLEDRIVAVV
                     NTDLIMLSELKRDLLPDQERLRKLYSGEDLERRLKTAEAMAVTKMIERKLQLQAAKNK
                     GVEVSDQEVTQAVQEMKKQGEALNQADPNTTRSVREQLTLMRVVDREVRGLIMVADSE
                     MKRYYEEHQDRFAYPEEYQLSQILIKPRTPDGLSVAQGRAEALLATLKQGEPFEDLAL
                     RFSDGADASRGGRLGLVRQGELIPALEQALTSVPVGQITGIVETAEGLHIVRVDDKKP
                     RQFRPFEQVKAEIQSLVFQQKTEDQYQIWMADLKNKAYIEIKF"
     gene            complement(38634..39530)
                     /locus_tag="PK063_07780"
     CDS             complement(38634..39530)
                     /locus_tag="PK063_07780"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: protein motif:HMM:NF024545.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HMZ96986.1"
                     /translation="MTSPQTPDISPWRARLTGTALALCALGSLAGCTEPPQEEPVIAM
                     INGRSITQAEFDIRWEELSQATRARYEKEGGKRRFLDELIMRELLMQEARKQGLDQSD
                     DIREKTLRYREQLILDELLKDRIKTKVEVSKEELDAYLEKHANQLLANPKVQVSVMLL
                     PNVYAAKDLKRQVEGGGNFTRFALRYSIDERSRAKGGDLGPYRKGLLEPELDALIPSL
                     HPGVLSDPIKTDKGYYLMKVSPLEPEILQADQATRERLRQELLAEKRRKRLDDVFAEL
                     RTGATIRMADAARYVTDEPGRP"
     gene            complement(39562..43035)
                     /gene="mfd"
                     /locus_tag="PK063_07785"
     CDS             complement(39562..43035)
                     /gene="mfd"
                     /locus_tag="PK063_07785"
                     /inference="COORDINATES: protein motif:HMM:TIGR00580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003690 - double-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HMZ96987.1"
                     /translation="MPPVVPSHLTNWFAPAREALRTGSGKPCLMGLHGSTAGFGLALL
                     TLSAPAQPLADRSWLVVAKTDDEAERLYRDTLFFRTLCGQSGDDLALFPKWETLPYES
                     TVPHIDLVSRRMQTLNRLCTTARTVLFTSVPALTQRVLPALVFTESILQFQPNSDLER
                     EVLVSSLLRLGYRKGSVVEIPGEFSIRGGIVDIYSTAYPDPLRVEFLGDTIESIRFFD
                     PATQKSTDKIKQAWVLPARELIRPDDSPDALAPLAADAEWHAPSVYGAMDSLLDYFPQ
                     PPVLVLDQPGALKAHTAECWQTIEEGYLRHEDRTDPNPYPTPDQLYFTWDQLVTATQG
                     YATLALEPVTAPDASWEPVLTCPAQTPASVGLGQRGTAFSQTLEVLDRLREGGPVVLV
                     ARSQGQVGRLLALFGEHDRPAMEWKPAALSAGGAQKAPFSVLNGEVSSGFLSPDLRLV
                     VLTEEELFAKGARHKPQHKSKAATFLSSLEDLNIGDFVVHMQYGIAKYQGLRRLSVQD
                     FDSDFLVLEFAGTDKLYVPLDRLSQVQRYAGADAHVPRLDRLGGTSWAKTTARVKKDI
                     EEMAHELVDLYANRELVHRTSYGKDSMLYHEFEAAFEYEETPDQRKAIEDIAKDLAST
                     KPMDRLVCGDVGYGKTEVAMRAAFKAVEENRQVAVLVPTTLLAHQHYDNFAERFAPFP
                     TRVALLSRFQSPKDTKAIIKDTAAGLVDVLIGTHRLLQKDVQFRNLGLVIIDEEQWFG
                     VKHKERLKQLRTQVDVLTLTATPIPRTLQMTMASVRDLSIIDTPPSGRLAIRTQVLRF
                     SEKAIREAILRELGRGGQTYFVHNRVETMERMGAWLQELVPEARIVMAHGQMDSKPLE
                     AVMLKFFHREADILIASAIIQSGIDVPTANTIIVNRADAFGLAQLYQLRGRVGRGGEQ
                     AYAYFLVPDEGNLSDDAQKRLTAIQQFTELGSGFRIAAADLEIRGAGNLLGKQQSGHI
                     AAVGLDLYLQMVEQAVQRLRGQVVEEEPDPTLRLSVSAYIPEDYVVDSHQRLSLYKRL
                     SSCGQLGDLALMHGEIEDRYGPPPDPVERLFELMQIRLLAKQLRLSSVVEQTHAVVIT
                     FDPKAKVSETAVQALMDRYKKRLRFLSPLSFELQMPHDDWSLVFPELNATLQTLHVCG
                     TNNQEPRTGST"
     gene            complement(43043..43525)
                     /gene="rfaE2"
                     /locus_tag="PK063_07790"
     CDS             complement(43043..43525)
                     /gene="rfaE2"
                     /locus_tag="PK063_07790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009244 - lipopolysaccharide core region
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1-phosphate
                     adenylyltransferase"
                     /protein_id="HMZ96988.1"
                     /translation="MPTKVTTRDELVSLLAERRQRQQRVVFTNGCFDLMHIGHVRYLQ
                     AARNLGDLLVVGVNSDGSVRALSKGPDRPIVPDVQRAEVLAALACVDYVVIFSEPDPG
                     ALIAALQPDILVKGGDWPLDRIIGRETVEARGGRVQTIPLVPGVSTTTLVQRIRSTTA
                     "
     gene            complement(43615..>43904)
                     /locus_tag="PK063_07795"
     CDS             complement(43615..>43904)
                     /locus_tag="PK063_07795"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96989.1"
                     /translation="RQRKFATPLNYDPDMWPEIRQALGDLLQPRLRYRLVGLGLSDLV
                     PAPEPLFDRRQRDAVAALDRLIERHGTGVVRLGALPQSEAGTRKRRPRTPD"
BASE COUNT         8751 a        12349 c        13361 g         9343 t
ORIGIN      
        1 gtcagcggct gattgccgga gaacgacaac agctgcctga cgacctggag ggtggacgtg
       61 ctggtttcga cggacgtcac cgcgtcgctc aagcgcggca cgaccaattc tttgttcccc
      121 aacccacgcg cgagccggtt tccattcaga tccagcttga aatcgatccc tgtgacggcg
      181 aggtcaaagt cgttgggatt ccggatacga agatcaacct gaagtcgccg ctcaaaggca
      241 ctcccctcca gcggcgtcac attcgtgacc agcacttccg gtggctcgcc gttcatcatc
      301 caggaggcgc aaccggaaac catcagcgcc gttagtagtc ccgccactac acgcacgtag
      361 ttcatgctgc ctatcataca cacccatcca atcgattgcg acgcacgtaa agagttgaag
      421 aagggggcgc tgtccggatc gcggcagtcc ctatgctctg gtatgatgat cgaaagtcgc
      481 tcaggttcga gaggaggcgt ccaatgaggt ccatcatagg tcggttcggt gcccttgggg
      541 tgttgccgat ggtgctggca ggattgctgg tctcgcagag tcaggccgct gatccgtctg
      601 gcgccgccaa agcctatttc gccggaggct gtttctggtg catggaggaa gtgttcgaga
      661 aggttcccgg cgtcacggct gtggtcagcg gatatatggg cggacgagtc gagcatccca
      721 gttacgagca ggtgtctgca gggggaacag ggcatgccga gtccgttgaa gtggtgtatg
      781 acccgaccaa ggcgagttac accacgttgc tcgatgcctt ttggcacaat gtggacccgg
      841 tcacgccgaa cgcgcagttt tgtgaccatg gcagtcagta ccggtccgtc atcttctacc
      901 aaggggaaga gcagaagcga ctggcggagg agtcaaagcg cgcgattgaa cagtcccaac
      961 ggctgacgca gccgatcgtc accgaactga ccaaggcctc gcagttttat ccggccgaag
     1021 agtaccacca ggatttttat aagaagaatc cgatccggta taagttctat aaatttaatt
     1081 gcggtcgtgc gcagcggctc gaagaagtct ggggtgcacc gtgacggatc acgcttcctc
     1141 ccgggaggag atcgcacgtc tcttgcgaga ttgccgtact attgctgtgg tcggattatc
     1201 atcgaatccg gcccgcccgt cctatcgtgt ggccagctac atgcagcagc agggcaaggt
     1261 ggtgatcccg gtgaatccgc gcgagactga tgtattaggt gaacgggcct atccctcact
     1321 atcggatgtt cccggttcga ttgatctcgt aaatgtcttc cggcgatccg aggaggctgg
     1381 cgccgtggtc gatgaagcga tacgtattca ggccaaggct gtctggctcc aggagggagt
     1441 cgtcgatgag gcggccgctc tgcgcgcacg ccaggcggga ttacaggtcg tgatggatcg
     1501 ctgttggctt aaggaatatg ttcgatgtgt cggtgagtag agcctgcggg ccagggctgc
     1561 cgctatgaca cgagctctcc ggaaccgatc gcaggccatt gccggctaat ctttcttcct
     1621 tcgctcctcc gcttcatgcg tcagtttccc tcatttcctt gagcattccg ccgctccatg
     1681 gaatagtgac gtgacggtgc gctcacaccc gtcctgcacc gttcaccacg ccattcatcg
     1741 atggaggttc cggccatgat gcgtttgctc gcggattgtc gctctctgat gcttgtcctg
     1801 cccttgatgg ttactgcgac cggctgcgcc gagtctgcgc tccagggaca ttcccctcag
     1861 gaagacctcg ggatggggat cgtatccgga accttgggcg cgcaaagccg gtctgccgtt
     1921 tcctcgggcg agcaatccac cgcgtcagtc gtcggccaag tgcaggccgt cgagggcggc
     1981 gcctacctgg ttcgggatgt ccgcggacag gaacatcgca ttccccatga cgaaaacacc
     2041 agaatcgatc ggccggccca cgtgggcgat cgcattcaat cctggttcga tcggcatggc
     2101 cgtgccgtcc tcattcggag ccttgatgag gaaggccgct agggctgtcc ggtcgagacc
     2161 gcttctccca acgatgcaac agcctgaatg gaatacccgc tggagccgag tggcccgtgc
     2221 actctttcct ttagcggtgg cgggatgcct gatggccctg atgcctccgg ccagccggct
     2281 ggccttcgac ccgatcatga aggaggtggc gggccggcct accgccgaac ccattgcctc
     2341 gctcattgcg acctatgccg agcaatatgc cctcgaccct gcgctcctgc aggcggtcat
     2401 caaggtcgag tcgaatttta attcggacgc cgtgtcctcg aaaggggcga ttgggctcat
     2461 gcagctgatg ccgttgacgg cggcagcgtt ccacgtgttg gatccattcg atccgaaaga
     2521 caacatccgt gcgggtgctg cgctgcttcg cggattgctg gaccggttcg gtggagacct
     2581 gtcgttggcg ttggcagcct atcatctcgg cgaggcgcgc gtcaggcagg ccatcggtgt
     2641 accggcgctg cctgcaacgc agctatatgt caatcgggta ctcggccact atgaccgttt
     2701 tcgtgccgga accagccggc ttcccacgcg tgtgacgacg cgccgggaag aacgtcgtac
     2761 gctttggtct ctgcagcagg ctcctgaata acggcctcgc gctgattcgc aaggcggttg
     2821 gctctttcca gaacccacga tggctgtttg ccggttgcat tttttgtggg aacggcgtag
     2881 ggacatctgc cttgcgaggc aggatccgca aacttcatga atcaagacat gacctggaca
     2941 ttgagggtgt gatgaagaag agtgatcgta cagcccgatt ggctcaatcc gatatccgag
     3001 cgatgaccct agcctgcgca aaggtcaacg gcatcaatat gtctcaaggg gtgtgcgaca
     3061 ctcctgtccc tccggtggtc gtgcaaggcg cgcagcaggc gatgtcgcag ggacacaata
     3121 tttatgctcg gtttgatggc attgcggaac tgcggcaggc aatcgcagac aaggtggcgt
     3181 cgttcaatcg aatcaccgcc gatccggaga ccaatgtgac ggtgagtgcc ggcgcgaccg
     3241 gatcgttcca agccacctgc atggcgctcc tcaaccctgg cgatgaagtg attctgtttg
     3301 aaccgtttta tgcttaccac gtccaggcga ttctcgccgt ggagggcgtg ccccggtatg
     3361 tgacgatgcg gccgccggat tggacgatgg acgtgaagag cctggaacag gccgtgacgt
     3421 ccaagaccaa agccatcgtg gtcaatacgc cggggaatcc atccggcaag gtcttcacgc
     3481 ggcgtgaatt ggagcagatc gctgagatcg cctgccgccg tgacctgtca gtgatcacgg
     3541 acgaaatcta tgagtatttt gtcttcgacg ggcgggaaca cgtgagcatg gcctcattgc
     3601 ccggcatggc cgatcggacc attaccatcg gcggctattc caaaaccttc agcatcaccg
     3661 gatggcgcat cggctacagc gtggcggagg cttcctgggc gaaggccatc ggcgcgatga
     3721 gtgatgtgtt gtatgtctgc gctcccacgc ccttacagta cggtgtggcc gccggcatcc
     3781 gcgcactcgg tccttcgtat tacaaggaac tggccctgga ccaccaacgg aagcgcgatc
     3841 ggttctgcgg ggctttagcg aaagcaggct tgcctccagc cgtgccgcaa ggagcctact
     3901 acgtgctggc cgacgtatcc cgcctcccgg gaaacaccag tcgggagcgg gcgatgtatt
     3961 tgttggacaa gaccggtgta gcgggcgtgc cgggcgaagc attttttgaa gggacggagg
     4021 gcagtcgctt tatgcggttt tgtatggcga agaccgacgc cgacctcgag cgagccagcc
     4081 aggcgatcga acgattgacc tcataaactc agtgacagca ccagcatcct taccgcgcct
     4141 gccaggacgc agtcctcgtc atggttcccc aggttgcttt cttcccgcag acccatcgat
     4201 acaagccgat taacttccac agggaattca actggcggaa tccaaaattc tccaggatgg
     4261 ctgccagcaa cagtttcaac acgtcgcgct gatccgggta gacgtggaac gacatttctt
     4321 ccagtaaaag cgcactcacc gacaacaaca cgcccaggcc gatggccgcc acgagcagga
     4381 tcagccacgc ctggatcgag acgaatccca tgacaaaact gaagatcagg aagcagtagc
     4441 cgaacacctc aatggccggg ccgatccact cgaacacggc catgaacgga aacgccagcc
     4501 agccgatcgt gccgcccttc ggatggcaca ggagatcgag gttttttgtc aggctttcgc
     4561 acagcccgcg ttgccagcgg atgcgctgat tcttgagcgt acgcaagtcc tccggcgcct
     4621 cggtccaaca gacggaatcg ggcacgaagg tgatgcgata cggtttgtcg cccatccgca
     4681 gatggcgatg caggcgcacg accagttcca tgtcttcccc gatcgtatcc gatcgatagc
     4741 ctcctacggt gacgacggcc tctttccgga aaatgccgaa tgcgccggag ataatcagca
     4801 tggcattcag cggcgaccag cccagtcgtc cgaagagaaa ggcacggagg tattccacga
     4861 tttggaacag tgccagcaga ttggagggca atccaatctt ggtcaggaag ccgttttcaa
     4921 cgcggcaacc gttcgcgatg cgcaccgtcc ctccgctggc gaccgtgcga tggtcgtcga
     4981 gaaacggttg caccgctcgc cgcaggctgt ccggctggag aatggaatct gcatcgatgc
     5041 agcagaacag gggatagatc gacaggttga tgccggcgtt cagggagtcc gccttgccgc
     5101 cgttttcttt gtcgatgacg cgaagattgg tatgactcga ggagtgataa attcctctga
     5161 tttccgccgt aggcagttgc gtattacagg cttcggggaa cggaaacaga tcaaattctt
     5221 tgcggaggac atcgatcgtg gcatcctttg atccatcgtt gatcaccacg atttcatatt
     5281 ccgaatagct gagttgcagc agcgaccgaa tagagccggc gatggtggcg gcctcgttat
     5341 aggcggggac caggatgctg atctgcggtt cgaaaccggt gtaactgtgc ggcaggcttt
     5401 ccagcacacg ctcctgcagg tattgccgca ggtgaacgat cgcgatgaga tccagcatta
     5461 agtatccggc ggtcaggccg agaaagtaga gcaggaacag ccactcagaa gttgaaatga
     5521 gcgtgtctac ccacatcgat caatgcgtct ccgcgaggga tggtgtcgct cgagaccaga
     5581 ttgacgggaa atccgtcggt cggggcacag aggccgtcgg gcggcgcctc ttcgcgaccg
     5641 tgttatgcag tgctgccgtc atctccatcc tgtggctttc tcttgcgcag gcggaggaca
     5701 ttcccctgtc ctcgccgatt ccttccacga tccatgagat cgaactgacc tatgccggga
     5761 acagcaccga tccagccgtg gcattcagcg ggccagtgcc tcctgcgggt cctcttcctt
     5821 atcgaccgtt tttacccatt cttgaactgt taccgggatt cggggtggcc catgtctttg
     5881 gtccctgcca tggacaggcg gtacgaagcg actcgcatct cgaattggag tggactgccg
     5941 gggacgcggg acgttgtggt cagcgtatcg agctgcgtcc cgccggaagg ccgatggatc
     6001 tcatgtccta ccagatgctg cggcttcgtg ggcgagccac cggccaggtg gtggtagcca
     6061 tagaagatct ggccggtcat cagcgggagc acaaccagtc gctggcaaca gtgacgggga
     6121 catttgatct cactattccc ctgaaagaga ttggtcgcgg agtggacctt cgatatgtga
     6181 cggcactcgt cgtgtccgct gaaggaccac gcggccggat cgaattcgag cagctgacgg
     6241 tgtcgcaacg taatacggtg aagaagccac ccggtgggac tggtttctgg gtgtggaact
     6301 accgtgcggc gatacaggag ccacagccac tgctggctac ctgccgcagg caagcctgtt
     6361 cgagaatgct catccaaatg ccatcactca acgatgatga ggcgatctgg gaaggctacg
     6421 cgtcgttgat ggctcaggtg caggaggccg ggattgatgc actggcgctg gatgggtacc
     6481 ccgaagccat tcaggaacct caccttttgg ccgataaggt acagagactg tttcacctgg
     6541 tgcggggtgg tgcggtatcc ggcatacagc tcgatatcga gccgtatctc ttgcctggat
     6601 tcctcgatga tgacgggcag ctccgtcggt atctcggcgc gatcgagacg gtgagcgagg
     6661 ccatccacgg ccgcgccaaa ttgtcgatgg tgattccctt ctggctggct accccgaccg
     6721 tgggtggtcg accgctcgcc tatgccgtga tggatcgggc tgatgaagtg gcggtcatga
     6781 gttatcgtac cgatctcgag gaagtgcagg acatcgccga ggacatcctg cggtatggcg
     6841 atgtgagtga gaagccggta tggctggccg ttgagacaac ggtgttgccg cttgaagagc
     6901 atgtcgtgct gcggcgtgat ctccgtccgg accgcgccga tgccttgtta gatcgcgagc
     6961 acaaacggct acggtggaag ccgatctccg aggccgaccg gctgacggga tccggcgaat
     7021 ggttccgcat ccatcgtcga tttacggtca ggcccgaacg tctgaccttt gccggacgtt
     7081 cccgcgtgga agtgtcccag gctattagtc atatgctcga caccacgatg catccgagtt
     7141 ttgctggggt gattattcac gatctcgatg gattccgggc cctccccgaa tagggcgtgc
     7201 ctgttggaag cacagagtct tcacggatga acgactcctt cacctggatc aatcaacgaa
     7261 cgtctatagc agggctgctc gcggtgattg cgtttgccgc ggcgtggttc tttgcacccg
     7321 cgacgatgat tgccgccatg gcgccggagc tttctccccg ccagactctg caacaagcca
     7381 gagtcttgga ggacgagaag cggtacgagg aagccattgc ggcgtaccgg caatacctcc
     7441 aggccaaacc tgacgatgac gatgtccgtg cgtcggtcgc caaacttctg tcctggcagg
     7501 gccaatggga cgcggctgcg gccgcctatc gcgacctcct gaccaggcac cccctcgatc
     7561 acgacatccg ggtcggtctc gcccaagttc tctcgtggca gaaacactat gatctcgccc
     7621 gagaggagta cgagcgggtg ctccacgacg aaccggacca tgtcgaggcc ctcaccggcc
     7681 tgggcaatgt gtacttgtgg agcggtcatc aggatcaggc cattccgtac tatgaacgag
     7741 tggtcgcatt gaccggcgat gcggacgtgg ccgcgcgcct tcaatccttg aaggccgctt
     7801 ctcgttcacc ggtcgtccct gtcaatccgt ccggcgctgc tgatgggaac gattccctga
     7861 ccgctcacgc cgctcaaaca ttggagcggg gccgacgtct ggaaacgatg cgtcaatacg
     7921 ccgatgcggt gaccgtctat cgcgaggaac tgcaactgtc gccgacgaat gacgaggtgc
     7981 gcgccgcgtt ggcacgggtc ctgtcctggc aaggggttca cccggaagcc acgacgttat
     8041 atcgagagat cctggcgcgc catccccagg atcaggatat tcgtgtggca ctgggacaag
     8101 tcctctcgtg gcagaagcaa ttcgaggaag ccggtcgcgt ataccaggac gtgctccaat
     8161 cagacccgac gcatgtcgag gcgaggcgcg gcctcgccga tgtggctcat tggcagggac
     8221 attacgcaga agcggttcaa cgttatgaag cgttggttgc cgaaacacac gatcccgagc
     8281 tcgaagccca gctgaagact attcgctcgg aatggcgcac gacctcgcca caggttgccg
     8341 agcaccctgc gtcaactcac gactcccagg gcacggacga gcgagttatc ggggccgccg
     8401 ttgaagaagc cacgaaattc gaagtggcca aacaatatcc tgaagcggaa cgcgtctatc
     8461 gcgatgtcct gcgccggcac cctgacaatg acgacatccg cacggcgctg gcgcgggtgc
     8521 tttcatggca gggcgctcac gcggaagcga cgaccctcta tcgtgaagtg ctggctcggc
     8581 accctgagga tcaggacatt cgcctcgcgc tggcgcaagt cttgtcatgg cagaaacaat
     8641 ttgatgaggc ggaacgattg tacggggcag tctcgcaggc cgagcccact cggatcgagg
     8701 ctcggcgcgg actggccgag gtagcccatt ggcgtggcga tcgatccgaa gcgttgcagc
     8761 ggtatgaggc cctgctggac gacacgcatg acccggcgat tgagcagcag atcaaggcgg
     8821 tgaaatcaga attgctcgtg tcgccgcgcg cggccgtcgg acaggggctg gccggcctgc
     8881 gtcttcccta ccgggactac gccaagatcg gctacggcca ctatacctat acgaagaatc
     8941 agccggatga acgcgacctc ttgtttgaac tcgccaaacc gctcggtaat caaacgctgg
     9001 tgatgcgagt ggaaccgatc aatcgctttg gatttcacga cacgccaatg tcagccgagc
     9061 tctatagtcc cttgtggtcg cgggcctggg ggtacatcgc ggggcaggcc acgatcaatc
     9121 cgcatttctc gcccaactat tcctttgtcg gcgaagtcgc gcaaggcctg ggcgggctgc
     9181 actcctcact ggcaccgttt gaagcgtcgt ttggttaccg gcgtttgaat tacaagcacg
     9241 atgacatcga tctattgatg ccgggcctga cgatttttct tcccttcaat ctgtggctga
     9301 cggagaaggt ttactttatt ccgaatacgg gggccgtcac actggcctct cagctcacct
     9361 ggcggccggc cgatcggttg caattcttcg cctccggctc gttcggcacg tcaggcgaac
     9421 gcatcgtagc ggcacaagac tttacgcgcg tcggaagtcg cacgattcaa ggcggcgtca
     9481 cgttcccgat taatgaacga ttctccgccg aaacgtccgg atactacgaa gaccgggggt
     9541 tcctctatgt ccgacggggc gggaacttca acctcatcta tcattggtag gtctatgcaa
     9601 cggtccacgc tcgtccgtgt gtcaggtatt gctctgctct ttgtgtctct cgtcattggc
     9661 gtccggattc tcgtcagtgc tcctcccgtc cagcacatgg aggttccgga gaaagacttt
     9721 catcgtttcc agggggtggc gggccccgac gacgcgacgg tcgtgccgcg ccacgtgccg
     9781 accgcgtgga cgacctacga accgggttcg acaagccggt tggccattct cttaaccgat
     9841 ccggactcat cgtggctcgg gttggcccac gggttgaaat ccatcgggat tccctttcgt
     9901 atgacgcgca atgttcatga ggccttggcg cataaggtgg tgcttgtcta tcccatgata
     9961 tccgggaagg tgttgaaacc ggaggaactg caagcactgg cggaatttcc gaagacaggc
    10021 ggcacactga tcggggtgca agtgctgggt ggcggattga atcacgtctt cgggtttcgt
    10081 gacgctgttg cctcgcgtca gcgctatgac atgacgttgg ctacggccga tcctctgttg
    10141 gcggatctga ccgacccgcg tgagcaacgg ctgcgggtcg gcatccgtga caagggtatc
    10201 gaggtgatgg gaacctatgg ttacaccgac gcgtcggctc cgcttgcgcg tttcgatgat
    10261 gggaccgccg ccgttacgca ggtggctcat gggcccggtc gagcctatgc gattggagtg
    10321 gatctcggct tcctcctgct gaagggatac aacaatcgcg gggaggagct ggtcaagaca
    10381 ttcgacaatg agttcgaccc gacgctcgat gtctggttgc ggctcatcaa agcgatgtat
    10441 cgcacggcgc aggaagaggc cgtgaccctg ggaaccgtgc ctttcggcaa gtcgctgtcg
    10501 gtcatgatga cgcacgatgt ggattttaca cagtccatca aacacgcggt tgagtatgct
    10561 gagtatgaga aacgccaggg cgtcgtcggc acgtatttca ttcaggtgaa atacattcgc
    10621 gattataacg acgatatctt ctttaacgac gagggcgtcc ggtatgtgaa gcagttagcg
    10681 gatctcggca tggagttggg tagccatacg atcgcccatt cacgcgtgtt caatcagttt
    10741 cccatgggaa gcggccgcga atcctatcca tcgtatgccc cgttcgtgaa ggatcggacg
    10801 acggcctaca atgtgagcat cctgggcgaa ttgcgagtga gcaagtttct catcgatcac
    10861 ttttccggcc aatccatcgt ttctttcagg ccaggcgaat tgtccaatcc ctttggactt
    10921 ccgcaagcgc tcctggcgac cggctatcgg tacagttcca cggcgacggc gaataactcg
    10981 ctgacccatt tgccatacca actgaattac gatcgtctga ccgacagcga ggtcgagatt
    11041 tttgagtttc ccgtgacgat cgaagatgaa gcgttaccga agatgggaga ccgtcttccg
    11101 caggccctgg aggtcgcgaa acgtatcagc cggtacggag gctctgtcgt cgtgctcatt
    11161 catccgaatg tgctggatca caaactcgcc tttgagaaag ggttcgtgga gggcgtgcga
    11221 acctacgcgt ggttcggctc ggtgggagaa ttcggacgat ggtgggcggc gcgtaatcgg
    11281 gtggaggtcg atgtcgtgcg cgatgccgat gccatgcggg tgacgttgaa cgttccagtc
    11341 tctttggcgg gcttgacgct cgaggtgccg cccggatggg aggtggcacg ctcaggcaac
    11401 ccgctgcggg gagtggcgca acatggaacg atggtcacat tccctcaatt gcagggcacc
    11461 tacaccgtcc tcttcacgcc cagttctttg accccgtcgg cttctcgcac gtcgtcatcg
    11521 cgttcgaaca cagtgaacat gggcctgtag tgaaggagcg gtgtgcgcgg tcatgcgcta
    11581 ggcgatgcga gccggatgct gagccttcgc attcgattga gccataaaag gaaccaagtg
    11641 ttcctgtgac tcgacggtgg tgagtgtgtt gtgcacgcgg gtcagacgct ccgtggtcat
    11701 ccaggggaga ttcgacaacg cttcagcggc ccggtagcgc acccaccaat gctcatcatc
    11761 caacagggcg atgagtcgtg cttcatcttc ctcaatcccc accttcccca atgccgacgc
    11821 cgcttggagt cgcacatacc aggttggatg cgagaggtgc gtccggatcg tcacgatatc
    11881 tcgaggatca ctgcattctc cgaacaggaa caggcaggct gccagtagat catcggacgg
    11941 cgtccctttc tgcagcatgt cccgtaacgg cggcaaggca tgctggcttt gagtggctgc
    12001 caggtggcga atcaaccgcg acccgatttc cgggctggca aggcacgcag ccttcgctat
    12061 ggcttcagcg gcgatgtccg cacctgccgg ttcgaagatc gccacgactt tgagcggaga
    12121 ccaatccttt cgctggctga tcaccggaat gatcaggggg acggcggctt tcgcatcgat
    12181 atgcagcagc gctttggctg cgacgaggga gacgaacgcg ttatcggcct ggagcgcggc
    12241 ggcgagctcg ttccagatgg atcgttcttg aaggtggccg agcgtcacga tcgcgagcaa
    12301 ccggcgccgg agcagccggg catggaggag ttccttcgcg aaccgatcag tgcccgttcg
    12361 ccgggcaagt tctttcagat tttcccgggc gtctccacga atagactcgt agcaatgatt
    12421 ccagagatag agcaggacga ggtggtcgcg ggtcgtgagt ggaggaagcg tctcaggcac
    12481 ttcgaccaca cattctgcca gtatcggccg ccagatttcc gtgacggcgc gtcgacgccg
    12541 gtctttgttg ttgcgtatgt atcgaagcag gagaatgcca aggaggagaa gcaatacgga
    12601 ggaatagatg gaaatggccg cgatggtgcc gatgcggagc gtcaggtctg actggtcgag
    12661 gcccagcacg ccattcctct cggcgctcgc tcaggccgca tgtgcgacaa agcgcttcag
    12721 ccgactcgtc agttcgcgcg ggttgaacgg cttgatcata taatcatttg caccgctctc
    12781 caaggcgcgc ttgatatcat gctcgctccc gtcggccgtc aacatgacga tcgggacttt
    12841 tttccagccc tcgcgctttc tgatgacggt gagtacctgc aatccgctta agaaaggcag
    12901 catcacgtcc aacagcacga tgtccggagg cgcgatggta ttgacgagct cctgcgcctg
    12961 ccggccgtct ttggcatgaa cgacctgata gttggcccgc tccagcagaa acttcaagag
    13021 gctcgccgtg tcttcctcat cttcaaccat gagaaccctg agtttgggtg tttcggggtt
    13081 atccatacat cgctccttag gtatcgatga gtgaggggcc tgaatattca gattgtcctg
    13141 atccggacga gttcattctt ttgtagcacg gattcttaca aacacatgca tacttcttga
    13201 ttttctcact ccccggcccg gccaccgtgc tgcatgggca gcgtagagtc attgagcctg
    13261 ccaccgacca gatacgtgag cacatggggc ctcgtcattc gtacgtgatc tcaactctgg
    13321 tgaggtacga ggccagttcg agcaagtcct ggcgaatgga tgttccgttg gcgaccttgg
    13381 ccgcctcctc cattcgaccg gcgatggtcg tcatggcgtg aaacccataa ctgccgctga
    13441 cacccttcat gccatgagcc agttgcctga tggtcgcaaa gtcgcttgtc gcaagggcct
    13501 ccgtcatcgt cgcgagttct ttgttccggt tggccatgaa tttcggaatc agcggttcaa
    13561 acgcagagtc gaccaggacc acgatcggtc cggcaccgca gctggacgtg acaggtgcca
    13621 tgtcgctcat gcggcagact ccttgcgtga gaagggagcc gcatagcgtt gaatggcttc
    13681 cagcagcgtg accttcttca gcggtttcat cacatgggcg gtaaatccgg cggcctgggc
    13741 cttcccgatg tcttcgtcat gggtgttgcc ggtcagggcg agaatgggcg tctcgctccg
    13801 ctgctgctct ttttcccatt gcctcatgag gcgaatcgcg gcgtagccat ccatgaccgg
    13861 catctgaata tccatgagga cgaggtcgta ccggccggat tgaaacttct cgacgcctgc
    13921 cgcaccgtgt tcggccagat ccaggcgata cggaaacgcc ttcagtaaga gggaaaccag
    13981 gacgcgatta tcttccatat cctccacgag caggatgttc agaggagacg agtgagaggg
    14041 attctgagcc tcgccccctg cgtgtttatt gtctgaagat ggcatcatca acaggtctct
    14101 cccaattgga tgtggcagcc ttcgccgggt tgcgagagga actcctgcct cgtgcaaaat
    14161 cctggcgtgt cggaatatcg gcgcagatct ttcctgccga ttctttatcg gttgggaccg
    14221 cgtgaccttg agatattggg ttgatgagag atttctcaat tacttagaag ggacattccg
    14281 ccgtgtggtg ggatcggtgc ttggtcggaa gtaatcaatc cagagtggtg gaaatgagca
    14341 aaatttgatc gcagccttga gcacatggga tacgcatggt atgtacagta ttaccctgat
    14401 gcatacaggg ggaaggaaac acccgggatg aatagaatga aacagaatca atggtttttc
    14461 ctgatgatgg gtctgagcct gttaagcatc caggcctgta gtcatgcgcc acggcctcaa
    14521 gaaaccacgt ggaccgaacc gcccgccggg gaaatttcct tgcctcgcgg ggagcacgca
    14581 gttctcgcgg gtgaatggga atatgaagaa ggcgggatgg tggtgccgtt gagattagat
    14641 cgattcggaa acgggtccta cgattttaaa gacggacgat tccggacgga tctgttttcc
    14701 gaccaccgat gggctggagc ctgggctcaa cgagaaaatg atcgggaagg gggctttgag
    14761 attaccctgt cccccgacta ttccgaaggc gaggggcggt ggtggtacac gcgcattgaa
    14821 ggtgacaaag ctcccaccaa ggccggcggg cgatttcatg tgatgaaggt acaatcgatt
    14881 gtggacaatc agccttggcc ttccgcgcgc tgattcctac ccgtgctcgg agccgagggg
    14941 atcgatctgt tcatagatcg ccgaatagtc cacgtctcca aggcctgcgg caatcgtgtc
    15001 gatgaggagt gaccggactc cctgaaggcc ggccggcgaa aggcgggcct tttccgcagc
    15061 ggacagggcc agctccacat ctttgaggag atgccgcgtg gaaaagttcg gttgagcata
    15121 gttccgtttc tccaaccggg atagtttctt ctcgaacatc ggcgcgtaca gcgcgctctt
    15181 tcgcaccact cccataaaat cattcacatc gacgccgcct cggcgaatga ggcccagact
    15241 gaatgcgaac gccgccattt cagcggcgat gagctgattg agggccagct tcagtacggc
    15301 cgcttttccg accggcccga tcaggcgcac ctcttccccg agataacgca gaagcggagc
    15361 ccacttgtca tagtgctccg gggtcgcacc aaccatgacc agcagcgtgc cggctttggc
    15421 ttccgcaatg ctgccgagca ccggcgcttc aagataccgg ccgccgagac ctgtgacgtc
    15481 tttctcgagt gagcaacttt cggccggtcc gatcgtgccc atttgaatga tcgtgcgccc
    15541 gtcaatcgcg cgactggccg cgggatcgaa caacaccgca cggatggctg cggcatccga
    15601 cagcaggagg agcacgacgt ccgctgccga catggcctct gcggcagtca gagcgatacg
    15661 gatgccttgc tgccggagtg cctgagtctt tttgatggaa cggttataga ccgtcaggtc
    15721 gtggccggtg gcatgcagcc gttccgctac gccctggccc aacaatcctg tgcctaacaa
    15781 ggcgacgttc atggaatacc tctcggatgt agccaatgcg gccatcgtac agagacgcgc
    15841 gcgcgttgaa aaggctcaaa gcggatggga tgcggccgcg aggccatgtt gaatcaggcg
    15901 ggtgcgcacc ggcgccggga ggtccgaccc gacggccagc gttcccggta agcgcgggtc
    15961 tgggcgattg aaggtgacgg gatgaccagc ggcggtcgtg gcgcgccctc cgctttcttc
    16021 taccaacaga actcccgcag ccacgtccca ttcatttccg ccggccaggg tgatcgccgc
    16081 atccgcttga ccggctgcca cgagcgcaag cgcgtaggcg atggatccga ttgggcggca
    16141 gtggagatgg tcctgcaggc cttcgaaccg gccgacccgg agttcccatg gattgacgag
    16201 cgcgaccggc cgttcggatg aggtgaagcc cggttgatca gaatccgaca gtcgttcgac
    16261 acggaggcca cgccctcgaa tggctgaaaa aaactcgccg gtcgcggggt taaaaatggc
    16321 tgccacggtc ggcactccgt tttcgaccag cgcgaccgac aggcagaatt ccggcaggcc
    16381 ccgcacgaac gaacgcgtcc catcgatcgg atcgacgatc cagacacgct ttctactcaa
    16441 gcgtgtgtcg ttgtccgttg tctcttcgga aagccagccg tcctcgggaa aggctgtcga
    16501 caatctgtcc tggagaatgc gattcacagc caggtcagca gaggtcaccg gtgactgatc
    16561 ggctttcgta aacgtttcaa atcctgcgct ggctaagcga agcgcttcac ggccggcttc
    16621 actcatggct tgcgacagga tggtcagttc gtactccata gtcatggctc ccgggaatgg
    16681 gcgagtcttc ttctcttcaa cctaccaggt cttgggacgg gaacaaagcc cgacgtcgct
    16741 tcatgcggat gctgcggctc ttgaccctct tgcaggttcc gcgtacaagc tggcagtacg
    16801 atgaagttga aacacaaaca ttcacgtaag gcaggcctcc cgcccggcac actggtccat
    16861 atcggggaaa agaggtcgga gacggtcacc attaccgtct acgaatacgg cgaaggccag
    16921 taccaggaac gcacggtgtc caagccggac gaggtggtgg cgacggggga gccgaccgtt
    16981 cgatgggtgg atgtcggcgg catccataag atggaggtgt tggaagcctt cgggaaaatg
    17041 ttcggcctcc acccgctatt gctggaggat atcgccaaca ccgaccaacg accgaagctc
    17101 gacgattacg gcacgtacgg ctatctggtg ctgaagatgc tctacgaagg ccaaagcgag
    17161 ggcgacatca atgttgagca ggtcagcctg gtgttcggag agaattttgt gctctcgttt
    17221 caggagaacg gcggggacgt ctttcaaggc gtgaaggaac ggctacgcaa tgggaaaggc
    17281 cgtttgcgcc atgccggcgc ggattacctg ctctatgcct tgatggattc gatcgtcgac
    17341 cgatacttcg tcattctgga aacactggga gaaaagatcg aagcgttaca ggatctctgt
    17401 gtgacgaatc ccggtcctga gacactgcgg gacattcatg cactcaagcg gcagctgctc
    17461 tttttccgcc gctccgtctg gcctctccgg gacgtgatga acaacctgtc gcggtcggat
    17521 ggacaatttc tccaggggtc caccaaagta tttttccgtg atgtgtatga ccacatcatt
    17581 caaattggcg acacgatcga aaccctgcgc gaaatggtct cgtcgatgat ggaagtgtat
    17641 ctgtccagcg tgagttatcg cttgaacggc gtgatgaagg tgctgaccat catcaccacg
    17701 attttcatgc cgctcagttt catcgccagc atctatggga tgaatttcga gcacatgccg
    17761 gagttgaaat cgccctgggg atatccggcg gtactgggcg tcatggcgtt gaccggactg
    17821 gcgatgctgt acttcttcaa gcaaaagaag tggctctgaa tcaggagatc agtccagaac
    17881 ctcgacacga tccacgaagt agggggtttc accgaaacag gtcgtgggga tatagcgaaa
    17941 ctctttgtag tgcaggacga cccgcttccc catctgcccg tcgagtttct tggccacgtt
    18001 ctcgtcccac accgtgaagc tccacagcac cggggcgacg cctggcacgg tcgtcatcgc
    18061 cagctcaccc tcctgcgtct tgcaaaacca tccttttcga gacagttttt gcaggtaccc
    18121 ggcacggtcg ccgtccgagt agctccaatt aaagacgatc agcaaatagg ctgcaccgcc
    18181 gaaaaacaac aacgtgaaga gaagtttggg tctccagagc caggctacag gaaacagaag
    18241 ggtttcccac cacgtcatag atctcctttt ctgacggtta cctcacgtct tgaaacagcc
    18301 agggtgcttg agtgcggcgg cgttgctcat attcgccgat ttgcgctgcg tgctggagcg
    18361 tcaggccgat tgcgtccaat ccgcgataca gacagtcctt tcggaatgga tcgatgtcga
    18421 agtgataggc catgccctta ggtgtgttga cctgctgagc cgccaagtcg accgtcaacg
    18481 tgtagccatc atgtgcagcc acgccctcga acagcgcttg aatttctgca gccttcagga
    18541 cgaccggcag aatgccgttc tggaagcaat tgttgtagaa aatgtcggcg aagctggggg
    18601 cgagaataca tcggaatccc tggtcgagca gcgcccaggg ggcatgttcg cgagaggatc
    18661 cgcagccgaa gttgtccctc gtcaggagga tcgaggcctg ctgatagcgc ggctggttca
    18721 ggaaaaattc aggatcctgg gatccgtctt ttcgtcgccg ccaatcataa aacaaccctt
    18781 cccgaagacc ggtgcgcttg atggttttca ggaactgctt cggaataatt tggtcggtat
    18841 cgacattgag ccggtccagt ggcgcgacca ggccggtgag tgtggtgaat gcgtccatgg
    18901 tatgtccttt tgtgcgtcgt gtctgccggc cgctgtgatc agcggacccg gcgtcaggaa
    18961 cgaattgtct tcctgcttat gaccactgac gaatatcgac gaaatgtcct tcaatcgccg
    19021 ctgccaccgc catggccggc gacaccagat gggtgcgtcc cccggcgccc tgacggcctt
    19081 cgaagttccg gttgctggtc gacgcgcagc gttcgcccgg ctgtaacaca tcggcattca
    19141 tggccagaca catgctgcag cccgcctcgc gccattcgaa gccagattcc ttgaaaatgc
    19201 ggtctaagcc ctcctgttcc gcctgttgct tcacgaggcc ggagccgggg acgaccatgg
    19261 cgtgcacgct gccggcgacc ttcttgccct tggcgaagga ggcggccagg cgtaagtctt
    19321 cgattcggga attcgtgcag gatccgatga agaccttgtc gatcttgata tcccggatcg
    19381 gcatgcctgg tttcagagcc atatattcga tggcgcgttc cgtagcctga cggagtttgt
    19441 catcgctcat gctgcggggg tccggcacag tgccatccac gccggtcacc atgcccgggc
    19501 tggttcccca cgtcacctgc ggcgcaatcg tctcggcacg taattccacg acggcatcgt
    19561 acttcgcgcc ggcatcggtg tggaggttcc gccaggctgc gacggcctgg tcccacaggg
    19621 tgcccttcgg cgccatcggg cggcctttga tgtagttgaa tgtggtctcg tccggggcga
    19681 ccatgcccgc gcgtgctcca ccctcgatcg acatgttgca gagcgtcata cgcccttcca
    19741 tgctgagcgc gcgaatggcc gaacccgtat attcgatgac ataacccgtt ccgccggcag
    19801 ttccgatctt gccgatgatg gcgaggataa tgtctttcgc ggaacaacgc ggcgagagtt
    19861 ggccgtcgac acgaacttcc atcgttttcg gacgcttctg cacaagacat tgcgttgcca
    19921 acacatgctc gacttcgctg gtgccgatcc cgaaggcgag tgcaccgaac gcgccgtgag
    19981 tcgaggtgtg ggaatcgccg cacacgatcg tcatgcccgg cagggtgaat ccttgctccg
    20041 gcccgatgac gtgcaccacg ccttgccgga tgtcgttcat gccgaagagg gtgatgccaa
    20101 acgtcttgca gttatcatcc agcgtttgaa tttgtttggc gctcaccgga tcggcaatgg
    20161 cgacgcggcg gtcggtcgtc gggacattgt ggtcgggaac cgccagtgcg gcggcggatc
    20221 ggcgtggagt gcgacccgcg accgtcagcc cttcgaaggc ctgcggcgag gtaacttcgt
    20281 gcaccaaatg gcggtcgata tagagcaacg tggttccatc cggttccgcc cgaaccacgt
    20341 ggtcgttcca aattttttcg aacagtgtct gtgcagccat ggccatgctc cttataaacc
    20401 cgcgcccttg cgagagattg agggcgcggt gctcatcgcg gagctattat atatgcgacc
    20461 aggcccatcg catcaagggc aaaggggctc cggaaaaaaa tgcctcttca gatttcaaaa
    20521 ccgcgcaccg ataaggtttc catggaacag gaacctatca acgcggacca catcagcatc
    20581 cctcgctgga cgatcaagcg cgatccccgg gccctggggt gctccatctg cggttcggcg
    20641 atcgtgaaga ttaccgctga atggcgacag gtctcgttct gcacgtgcag actgatcgag
    20701 tatcgcgtcc tgccgcgagc tcccaaggcc ttacctgctc cctctcccgc ggcagattca
    20761 cgcaaagatc cttaatcccg tctgagatgg agatgcacat ggcgcgatgg cagtgggcgc
    20821 ttctggcggc gtgctgctcg gtcatgctgg cgtcgggatc ggccctggcg agtgatcgcg
    20881 cccatgcgaa gtcactgacg cgatccgggc tggccgttcc ggcctcgtcg ctgcgatcct
    20941 gttccggtga ggatctgctc ggtacctgga gcctggtggc attcgattct gcctatcgct
    21001 tcaaagatcc gcaggccccc tatctgtttc cctatcaagt cttccagtac tcgggcgagc
    21061 agggagccaa gtcagctcac tcgcgtaccc cgatgctcga cagcccggat cggatactcg
    21121 annnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    21181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ntgctcgaca gctatcgcca
    21241 ttgtgtcggt cgagagttga tggagcgggt ggatggggct gaagctcagg ctcaggcgct
    21301 gttcaccgcc ccgatcgtgg tggtctcaca tgggatgcaa gacgatccga tcctgaatta
    21361 cggatcgcaa ctcgcgctca cgctctggga gatgacctgg gagcagctgg tgcatatgcc
    21421 atcccgtctg acggcggaac cggtgaaccg tacggagcgt gaatcgatgc ttgaacgcgc
    21481 ccgcacccag ggatacatcg acaattaccg gggagtcaga atatcgagca gcgggcggcg
    21541 gttcctgatc gagcaggccc tcgtgtggaa tgtggtcgat cgggcgggtt atcgccgggg
    21601 gcaggcggcg acgttctcac gctggacctt cctctaaccg ccggaatctg ggcacgatct
    21661 cgccgccgat ggagaccgat tccgaaaaca tggtcatcgg tctgatccac aagccgcctg
    21721 ctccatagag ttgacgatag acgacgtatt cctcctcggt ttctgaatgc cgggccaccc
    21781 cgagcacttc atagtcgttc cctttatagt gacgatagcg accgggtttg atcatggtgt
    21841 atccttgcgg tttcgaacct gcgagcgagt ctatcgaatc aggcatgcca tcacaactct
    21901 ctcagaagaa cgagcgtcgg cacgatgtcg tggtcatcgg cggcgggtcg gcgggttatg
    21961 ccgctgcgcg gacggcgtgc gaagcaggag ccgatgtggc gatcgtcgat caggggccgt
    22021 tgggaggctt gtgtattttg cgtggctgca tgcccacgaa gaccattctc cggtcagccg
    22081 aaatcatggc gctcatgaaa cgcgcgcggg agttcgggtt ggcgcctgtc accgcccggg
    22141 ctgacctctc ggccatcgtc gaccggaaga accggctggt gcaggagttt gccgattatc
    22201 gcatcgccgc gttgcgcgat ccgcggttca cgctgtacga atcgcacgcc gaattcgtct
    22261 ctcctcatga gatttgtgcc ggagggttgc gcattcgagg tgacgcgttt gtgattgcca
    22321 ccggatccag tgtggcgaag gtggccatcc ccggattgtc tgaggcgggg tacgtgacaa
    22381 gcgacgaaat gctcgatgtg cgtcatgcac cggtctcgct cgcggtattg ggcggcggcc
    22441 tggtggcggt cgagttcgcg caattttttt cccggatcgg cacgaaggtc accatgctcc
    22501 agcgtggtgc gacgctgttg tccgatatgg accaggatgt cggtcaggcg ttggcctctg
    22561 cttttgagga cgaaggcatc gaagtactca caggggtcgc cttcgaccag gtgacctcat
    22621 ccccaaccgg gaaaaccgtg catttccggc agaatggtgt ctcgcacagc cggtcggctg
    22681 aggtcatctt tcatgctctg ggccgttgtc ctaacctgaa gggactcaat ctagaggcgg
    22741 ctggcgtgaa ggtcatcgat ggtcgcctcg tcgtcggggc tgatatgcgg acctcgcaac
    22801 cgcatatttt tgccgttggg gatgtgaacg atctcacgcc gatcgtccat ttggcgatcc
    22861 agcaaggaga aacggctgcc ttcaacgcga ctcatccgga tgtgccagcg cgggtcatcg
    22921 accatcggtt agatagcgaa atggtgttta cggatccgca agtggctatt gccggcctca
    22981 gtgagcgcca gtgccgtgaa caggcgattc cctatctgac ggcttcgtac ccgtttgccg
    23041 accatgggaa ggcgatgtgt ctcggagctc tcgcaggatt cgtgaaattg ttgtgtcgcc
    23101 cggacaatgg cgaactgatc ggcgcgcaga tcgtggggcc tgaagcggcg gaactcattc
    23161 acgaactcat cgcggtcatg tattttcacg ggacggcgca ggacttgttg cgcatcccgc
    23221 actatcatcc gacgctggca gagattgtga cctatccagc tgaatccatc ctcgagcaga
    23281 tggggcggat atgaggcggc ctgctctcgt cggtttgtgc gcgctcttgc tgttcatggc
    23341 ctggtcttgt gggcaacaga cgtgggaggc ggccatgcag gctggtgaag tggccgtgca
    23401 gcgaggacaa ttgggagaag ccgaacagat ttatgctgca gcgttgaaga aagcggagga
    23461 gttcggtccc catgaccggc gcgtcgccgt gaccttggcg catctggctc aggtgtatag
    23521 cacgcaaggg aaatttgtag aggccgaacc cgtctatttg gaagcgctca agatttacca
    23581 ggaggtccac ggcgagaacc acctggatgt cgcggccatg ttgaacaatc tcggggtact
    23641 gcatcgcaag cacggacaat tcgcggacgc acagcggctg ttgacccggg cactcgcgat
    23701 caaagagaaa cttctcggtc cggatcatct cgaggtggcc ttggcagtga gcaatttagc
    23761 cgccatgtac gccgctcaag gcgatacagc acaggcggcg gcgctcttcg cgagggcgtt
    23821 ggcgatcagg gaaaaacaat tagggcctga ccatccggat gtggccaaga gtgtgatcga
    23881 ttatgcggga gcgttacgaa agatcggtcg cactcctgaa gcagacgcgc tcgaggggag
    23941 agccgctgcg attcgctcga aaacgaagtc gtagatgaag ggaagagttg aaccgacctg
    24001 atgtgccggt gtagcgtaac aggttggtga gaaacgaggc gaacgatgtc tgatttgcgg
    24061 accaatgcat tgattgcgcg cggaatgggc atagtcttca ttgccggagg cttcatgctt
    24121 ggcatctacg ggttggagtt tcccaacacc atgtggctgc aaaccgcatt gggcttgctg
    24181 gtcaccggga tgatggctca agggtatgcg atgtattgtt cgattcgctg ggtgcgggaa
    24241 caacgtgact cggaacgata accgcttaag ttacgtgagc aatcgcctgc tgccgttgtc
    24301 ggttcgatgg agcaggttag gcatgctgtt gtgcctggcg atgttgtcag gctgcggcgg
    24361 accctggcgg gacacctacc tgaataaggg tgtgcacaag ctcacccagg ccgatatcga
    24421 agacaagttc ggcccaccga gcacggccaa gacgccggta ctaggcggcg ataccgtttg
    24481 gacctaccgc gtaccgatgg gagaccggga agttcatccc tgggatccca gcagcctggc
    24541 cgccggcaaa aaaaccaaag ccccgccttc gccgtcaccc tttggaaaaa gtctggctgg
    24601 taacgatgaa ccctatcggg agccgctgta ttgctaccgc tataccttgt catttgacga
    24661 gcaaaaacgc ctgaaagatt ggaaaagaga agaatgcgtg ccacgcacga gtgaggatgg
    24721 taccgtagtg cagtgacaat gacggaaaaa accatgcaag atatgctgcc ggtgatcggc
    24781 tccagtgtct tcttcgatct gctcaagtcc atccttctcc tccttatcct cctcattgcg
    24841 cgaacggttc tcgttcgatg gattaaaaat aaccaagcgc taaccatcga cgcgcggcgc
    24901 cggtggatcg tgaccacccg caatagcatg gtgctgtgcc tctttgtggg actcgtggtc
    24961 atttgggcgc acgagttgga agccttcgcg gtctcgctcg tcgcattggc ggctacctta
    25021 gttctggcaa caaaggagct gattctctgt tggagcggcg cggcattacg cgtcggcggc
    25081 ggggtctatg gagtcggaga ccggattcaa ctcggtacgt accgtggcgt cgtcctcgaa
    25141 tatgatgtat ttgccacgaa gcttctggag atcggccctg gtcagacctc acacttgtac
    25201 acggggcgaa ccgtcgtctt tcccaacagt ctgcttttcg gcaatccgct cattaaggag
    25261 agtccgtcgc aagagtatgg tttgtatgtc ttgtcggttc cgctcttaag cactgacaat
    25321 tggcaggccg ccgaacaagc cctacttggc gcggcaaagg tagagtgcgc cccttttatg
    25381 gatcaaatgg gtcggcaaat gaagttgctg gaacaacgaa atttattgga agccccttcg
    25441 cctgagccac gcatcacgat ccagcttccc gaggcggggc ggattcatct ggtcctgcga
    25501 tttcctgcac cggaccgcgg ccgatcgcgg gtggagcagg ccattctccg gcgctacctc
    25561 acgactattc gtcagtaagg ccgcttgtag ttcaagtgat ccgtctctct tgcggatggc
    25621 cgcgctctcg actgtaagcg accctcctcc ttgccgtaaa aaacggcaaa aaaattggca
    25681 aacgaaactc ttcggggtat tgatggatgc tgcaggcccg tcggattgcc gggatgcctg
    25741 acaccatatt caaccaagag gggggttgtt gatgagaagg tcaatcgctg tgatggtcgc
    25801 tgctgcattt gtgggcatga gctcattcgc cgctgccgac gatctgggca tgggaaaaat
    25861 gtccgagggg atgaagcagg atatgggcac cttttccgac gagatgaatg cccataaaga
    25921 agaactgaag agcgatctga aggcgaagaa agagtctgca aagagcgagc tgaaggcgaa
    25981 gcgggacgaa gcaaaagcca aaaagaaaca agccaaagcc gatgcgaagg ccaagaagga
    26041 acacgtcaaa gcgaaagtga aagcgaagaa agatgcggcc cgggcgaaag cggccgacat
    26101 gaaaagtgct gcggacgata ccgttcaaga gatgggcggc atgaagaacg acctgaagga
    26161 agcgacccgc tattaacggg tagacggaaa acggcgcgtt ttctcgcctg cggcctgtga
    26221 tcggaacctc ccgatcacag gccgtagtat tttgcagacc tcggttgttg cgcgtggtgg
    26281 gctctggtag aattcgcgcc cacgatgaaa gtcgccacct tcaacgtcaa ctcactgcgg
    26341 aaacgtcttc cgatcgtctt gcagtggctg gagcgccatc agcctgacgt gctctgcctg
    26401 caggaaacca aagtgcaaga cagcgaattt cctcttgccg cgctcgcgac gtcgggatat
    26461 gagatcacgt tccggggtat gaaggcctac aatggcgtcg ccgtactgag tcggacgaag
    26521 cctgaatttg tctgttacgg atttgacgat ggcggagaag cggaggatgc caggctgctg
    26581 cgggtcgtca ttcaggggat tccaatcatc aacacctatg tgccgcaggg gtttgagatc
    26641 gattccccga aatatcaata taaactgggt tggtacgacc gcttactgaa gcactttgat
    26701 atgcatctct ccccgaagga gccggcgatc tggtgtggag acatgaatgt ggccccaaga
    26761 cccattgatg tccacagccc ggagaaacat ctgaaacatg tctgctacca cgaagacgcg
    26821 cgcaaagcct atgggaagac aattgcgtgg ggcttcgaag atgtattctg caaactgtat
    26881 ccagatcgcc agcagttcac gttttttgac taccgtgcgc caagtgcctt agctgccaat
    26941 aaagggtggc ggatcgacca tattctggcc acagcgccgt tggcccagaa atgtcagcgc
    27001 gtcgatgttg atttagagcc tcgccgtgcc accgatgctt ccgatcacac cgtgctttgg
    27061 gccgacttcg atatgtaatg ccaccgtact ctacctcgcg tgctacaggg caggagcacc
    27121 cagtgcccct gccctgaggg ttcgatctac tgcaatacct cgaccggttc caacaataat
    27181 tgctcggcca tccgagtacg tcgattctgt tcgatcaacg gatccacgat cgatccgcaa
    27241 ttaatacacc gccagacaaa cgtttccggc gaaaaatcag gtcgccattc atccaccatc
    27301 agtcctttgc atcgtccgca tgtcatggtg tccacctcct taggatgtgc ctccaacgcg
    27361 tgaaggccgt gcccatgtga gggagagact aacagtggga gattaaagag gtgttagtgc
    27421 gacgttaaaa tgaattaatc aaaatttccc cgcgatatca ggagcttcac ttgtcctgct
    27481 tagacaaatt gagaagcagc gaggaacatt ctgtataaaa tctgacgtga aatgagagtc
    27541 gaaatggagc gacgcttgcg acaagaagtc gaattcttcc ctccttcaga ttgagcccac
    27601 tcagttacct catggtctac gcgcagaacc gttgagtttc ttgacagaac tccgaccatc
    27661 ctttatcgat tgaactggcg acagacgcga gctttccgaa aaatgtattg caggccacat
    27721 cggcaccgga atgtgctgga tgacgtccgc acaggatgta tagatcgtcg cgcgagccct
    27781 atcccgcgcg tgtgaaggag acaggccctg agaggcgccg attattggat atggcacaac
    27841 cgttgacttg cccgcagtgc ggccaggata aagttttccg ttccccctgc tcgactctca
    27901 tggagcggtt gcagtcgctc gcctgcatgt caccgtttca ttgccagtca tgcagctttc
    27961 gtttctcggc gtcccgcttc ggctatcggt acccggctcg aatgattgat cgtcgcgagc
    28021 acctgcgtat tcctgtccgc ctgtttttgt cgttttccgg gggaaaggtg cggggggagg
    28081 ggacggtgcg ggatatttca atgggcggtt gcatcattga aagtcaggca tcggtgcatg
    28141 aggacgatat cttttacctg caaatcgtgc tggagaatga acaggctccc atcgaagtcg
    28201 ctgccatggt cagatcggtg agttctcgcg gtatcgcctt caaatttctg cggtcagccc
    28261 aagaaaataa gcgcctactg gcgttcgtac agtccaagac ggactcggtc ggacctcgtt
    28321 ctcctgccta acgactctcc gctacgcagc atcgcctcgc gaatcccacg aaacttcagg
    28381 agaccccgag atccatcctg ctggccattc tgctagagtg gagtttccca ggcagaggcc
    28441 tgtgggtatt ccgtcgtaag acgctcgtgt tccgcgtgat cgaaatcttc tatgatgaga
    28501 tctgcctgac tcaatggttc cgggcacgca ggtgacgaca ggaaatcgac atagtcctgg
    28561 gctttagccc gggtagcaaa gcggcagaga ccatattccg gcatatggga cgaagggtgc
    28621 cagaaggcca acccgatcga gctgccttgg aagattccca aggcacggtg ccgaacctga
    28681 aagcctcccg gagtatcggt agaacgatcg agcgccataa gattccgttg cgacccaata
    28741 accttacccg ctgcgaagta taacaaggtt gtgagcgaag cgacatctca agcggtgggc
    28801 ggcagactgg atgattgact tcgtcgacaa aagccttaga tcttgaagaa gcgctgtcac
    28861 cgttcggcgc ggaggaggag cgatgatctc aatggcacga ttgatgggcg caagtttttt
    28921 actcgccggt ctcctggcct tgtccggatg cggctacaac gatctccaag ggctcgatga
    28981 ggacacgaaa gccacgtgga gcgaagtgat caaccagtac caacgtcggg ccgatctcat
    29041 tccgaacctg gtcaacacgg tcaagggcta tgcggcgcat gaaaaggata cgttggaagg
    29101 cgtggtgcag gcgcgcgcca aggcgaccag cgtgcagatc acgccggagt tactcaaaga
    29161 cgaagccgcc ttcaagaggt ttcaagaagc gcaacagagt ttatcgagtg ccctggggcg
    29221 cctgctcgca cttgccgaga attatcccaa tctcaaggca gatcaaggat tccgtgacct
    29281 tcaaagtcaa ctcgaaggaa ccgaaaatcg catcaccgtc gcgcgcaagc gatacatcga
    29341 caaggtggcg gagtttaata agatggtccg ctactttccc acgaatctga cggccaaatt
    29401 tcttctccat ttggacgaaa aagccaactt caccgtggcc gatgaaaagg ctgtggccaa
    29461 gccaccggaa gtgaagttct agcgtcggct tcctgtgaca ggagcaatgg cgatgcggct
    29521 gatgggccga gcagggtggg ctgtccttgc cggatggcta tggttcacgc tggtgccgag
    29581 ccttccggcc cgtgctctcg atgtacctcc gctcagcggc cgcgtggtcg acctcgcgca
    29641 tgtcctgccc cccgccacca cggctcaatt gtccgagacc ctccaggcgc atgaatcaaa
    29701 gacctccaat caggtcgcag tactgattgt tccttcattg gaggacgagc cgctgttcga
    29761 tttttcccac cgtgtcgcga cgacctggaa gttaggcgcc aaaggcaccg acaatggcgt
    29821 tctgctcctc attgcgatca aagaacgtaa aattcgtctg gaagtcggat acgggctgga
    29881 aggagtcttg acggatgcgc gatcggcgca aatcatccgc aatgaaatcg ctcccaaatt
    29941 tcgcgccggt gatgtcccgg ccggcgtcac ggccggtgta caggctgtcc tgcacactat
    30001 tgagggaacc tatagggcac cagaatcgcc gaccgctgtt cattccgatg gtgaggtgat
    30061 cggcaatacg attgttgccg tcattgtagg cgtggtcatt ggtctcttct tctctcgggc
    30121 tcaccgcgta ctgggtcccg tcgcaggagg gggactctcg tttctggtcg caccgtgggt
    30181 catcccggct cttatcgccg gcgccgcaag cgtggcgctg gtcagtttga tgagtggatt
    30241 gggacaagcg agcggaggag gacggcgaag ccgcagcggt ccattcgatg acacctggtt
    30301 cagcacacgg catggggggt ggggatcggg cggactgggc gattccttcg gaggatcggg
    30361 cggcttctcg ggcggcggcg gtgatttcgg aggaggaggg gccagtggcg actggtagta
    30421 agccggcact cactgaagct gagcgggcgc gtgtcgaggc ggccgtacag gccgccgagc
    30481 agcacacgag cgcggagatc gtacccctga tcgtggggcg atcagggctc tatcgcgaag
    30541 cgcatcatcg tgccggccta ttgagtgccg tgctggcgtt gacggtactt gtgacgatcg
    30601 aaaccgcctg gttgccttgg ggatggcagg cttcgaatgc cgtgtggtta gtcggcatca
    30661 cggtgctcgc ctattccgtt ggcgtctggg ttggaacctg gcccatgctt ctgcggctct
    30721 tcacttcccg ggaccgcatg cgtcacaaag tgcacatgcg cgcggaacgg gcctttgctc
    30781 aacagggcct tgcacaaacc cgtgaacgga ccgggctgtt gctgatggtc tcattgctag
    30841 agcgacaggt ctatatcctg ccggaccagg cactgcaggg gcgcatttca gtggatcagt
    30901 ggcaggacat tgtttcggtc gtggtggagc gtatgaaggt cggtgacctc gctggtggtc
    30961 tctgtcatgg aatcgaagcc gccggagttc ttctcgctcg ggcctgtcct tcccgtgagg
    31021 gcgataatcc caacgagttg ccgaatgcgg tgatacaaga tctgtgacgg ctggattctg
    31081 tcggacaata gacggcctca ctccattccg ctacaattcc gccaatgtcc gatcccgccg
    31141 cgactcctga accatctcaa ccagctgtcg atgaaaccca ttccgtcgtc aaggcggcgg
    31201 gtctgatcgg catcgccaca ttttccagcc gcattctcgg atttgtccgg gacatggtgt
    31261 tggccaggct gttcggcgcc acgccggccg cggacgcgtt ttttgtcgcc tatcgcgtgc
    31321 ccaatctgct tcgcgaattg ttcgcggaag gatcgatgtc cgcggccttc attcccgtct
    31381 ttaccgaata tcacaccttg aaagccaagc gtgacgcctg ggagttggct agtgcgacct
    31441 tcacgacgct cctcaccatc gtgaccgccg tgacgctggt cgggattctg gctgcgcccg
    31501 gcatcgtatg gctgctggcc ccggggtttc gagagagcgt cgacaagttg gccttaacga
    31561 cgctgttgac gcagctgatg tttccctacc tgatctttat cagtctggcg gctctggcga
    31621 tggggattct gaattcgtta cgtgactttg cagcgccggc cttctctccg gtctttttca
    31681 atatttttac gatcgcctgc atgctcttcc tatcgccgtg gttatccgag ccgatccttg
    31741 cggtggccat cggcattgtc gtcggcgggg tggcgcagtt tgccatgcag cttcctgggt
    31801 taaaaagacg cggcatgttg ttcggcctgc ggtttaaccc gggccatccc ggagtgaaac
    31861 gcatcggact tctgatggtg ccgtcactgc tgggcttgtc agtgacccaa atcaatatca
    31921 cggtgagcac gatcctcgcg tcctatttct ccggcgggcc cacgtatttg ttttacggga
    31981 tgcggttgat tcagtttccg ctcggtattt ttggtgtagc actcgccacg gctattctcc
    32041 cgactctgtc ggcgcaggct gcgcgcggag cactggatga attgcggacg accatcgggt
    32101 tcggcctcag gatgattttt ttcatcatcc tcccggccat ggccgggctg atcctcctgc
    32161 ggtacccgat cgtgcatttg gtgtttgagc acggatcctt caccaagacc gacaccctgg
    32221 cgacagcgac cgcgctgctc tgttacgccg tcggactctg ggcatttgct ggagtccgta
    32281 ttatcgtgtc cgccttttat tccctgcagg atacgcggac tccggccata acagcgggga
    32341 ttgccgtcgg ggcgaatatt ggcttgtctc tctggttgat gacgattctg gacgccgcag
    32401 gcttggcgct ggccacggca ttggcctcga tgctgaacgg aagtattctc gtagccgtgt
    32461 tgcatcggcg cttggggcgg gtggattggg gtgctgtcgt gcgatcggcc ggccgggtac
    32521 tggcggcctc cattccaatg gccggcatct gtctgtgggt ggcgagcgcg cccctgtgga
    32581 tggaaaccgg tcaatggatc gtgaagtccg tcatgctgtt tggggggatc gggttcagcg
    32641 tcatcgcgta tctcggcatg catctcatgc tagggtcgga cgagctggat gtggtcatgg
    32701 gattggtcaa gcgtaaactc ggccgggtcg cgcgaaaatt cggggtcgca tgaaatgacg
    32761 gagacgagga cctttaaaac gtcttggggg tggatgaccg tcacggcttc tgcaaaggga
    32821 gtgacgtcca ttgatttgtt tccgtctgtt cgcaccgttc gtcatgattc acacagagac
    32881 gaggccgcgg cgtctattgt gaaagaggcg caagcccagc tcttgtctta tctcgacggg
    32941 gagcgtcgcg agtttgcgct gcctatcgat tggtctgccg gcacctcgtt tcagcgaaag
    33001 gtgtggaagg cgattgcagg gattccttac ggccgcgtgc gatcctatca gtgggtggcc
    33061 atgcgtgtgg gtgggaagca gtatgccaga gccgtgggca tggcgctggg agcgaatccg
    33121 gtacctatcg tcgtgccctg tcaccgcatc attgcgcatg acggctcctt gggcgggttt
    33181 tcgagcggat taccgttgaa gcggcgtctg ttgggtttgg aagggacatt gacgcaattg
    33241 cgcaatgccc gataggtgcg aacgattgtg gcgaactcga gatgaaagcg gtcatccagc
    33301 gtgtcacacg ggcgtcagtc gaggtagaag ggcaggtcgt cggtcgcatt gacctcggac
    33361 tgctcgtgtt attgggcgtg gccaagggtg atggagaagg cgatctctcc tatcttgtgg
    33421 agaaggtaca agccctacgg atttttaatg acgatcaggg aaaaatgaac cgctccctgc
    33481 gtgatgtcgg aggagcgctg ttggtcgtct cgcaatttac cctgctcggt gataccgcga
    33541 aggggcaccg gccggggttt gacctagctg ctccgccgga ggcggcgcgt gcatggtatg
    33601 acgaggctgt ccagagacta cgccacgaag gcctcaaggt ggaaacgggc gtctttggcg
    33661 cgcacatgca ggtggaacta ctcaatgacg ggccagtcac gtttattgtg gatagccggc
    33721 gaccgggagc acacgcggac ctcaagtctt gatccgggat gccgataagg agtcagagag
    33781 aaagtccgct cggattgaga atggtctggt atactatttt cacagggcaa ggattgcccg
    33841 ggaggtcgag atgggaagtc ccgtgtcccg cagccatccg ctccggcagc tcttcggagc
    33901 attgacggag aaaagtttca ccgaacacct cgggtggccc gatctgaacg tcaccgagta
    33961 cgtctccaac ctgctcgtcg aattcgcgca caccgatcaa ctctacaaaa tccagaatac
    34021 ccagggccgt ccgctcgact cggtcgtcga gatgttattt gagtccgaag tcttgttgga
    34081 ggcacagtcg ttcgaacgtg agcgtgacgt gcatcgccac atcggcgact ttacgctgtt
    34141 tatgaccggg ctctttccgg aatatctccg ccgcctcaag agcgtgggga gaatctatca
    34201 caaggatttt ctggtcgatt acgtgaaagc cgggaagcgg tcctatggcc tggtcgcgga
    34261 atttggtcat tacgatcccg agcaggatac tccgttgttc cgcaagctgt cagaaaactt
    34321 tgagctctgt gtgaccggac tgggatttgt ccggtctgac ttggaccgta tgcaagatcc
    34381 tgcctgccgt cgcgtgaaag atctgctcct caattgaaac gcctacgacc ggttctcctc
    34441 gttcacggtg gcgcgggacg ccgcgccatg accgttgctc aagccgcctg cgtggaacgc
    34501 acgttggccg aaggccatcg tctgttgcag gccggtgtcc cggcgttgtc tgtggtcgaa
    34561 gaggccattc gattgttgga agactccggt ctgtttaatg cggggcgcgg ctccaatcgc
    34621 caactcgacg gcgtacgccg gatggatgct tcgatcatgg agggccggga ccttcgcgca
    34681 ggcgcggtgg cttccatcga gggcatcctt catcccgtca ccgccgcccg gctcgtcatg
    34741 gaaaaaaccg cgcatgtctt actggtcggg aagtccgcca gtcgctttgc agactatttt
    34801 ggactcgagc gcgctccgcg ttcgaggcga agcctgacag cccagcccaa gcaattgaga
    34861 ccagcagcgg gggtgagtcg aacgttgcag ctgcatcagg ccattgtgaa aaccggccgc
    34921 cttcgtgcaa ggagcttagg aaaagaaacg gtaggcgcgg tggcgttgga tgtgaaggga
    34981 accgtggcag ccggcgcgtc gaccggtggt gtcgatgtga tgttgcctgg ccgggtcggc
    35041 gatacgccac tgattggctg cggggtctat gccgacaatg acgccggtgc cgtatccatg
    35101 accggattgg gagagagcat cattcgggtt gccgtcgcca aggaaattgc ggatgggttg
    35161 gcgaccggtc tgagcccggt ggccgcggcc aaccgcgtgc tgcgaaaagt agtggagcgc
    35221 gttcaaggtg cagccggcgt cttagtgctc tcgccggacg gccggtgcac gattcgccac
    35281 agcaccccgc atatgattgc cgggatcatc ggcccggacg gacgcgcgat tgtgcgcgac
    35341 cggtttgcct agcgcagtca tcggctgata cagtgacacg aggtctcagc ctatgccggc
    35401 gctttttcat cttgcctttc ccgtccacga tttggccgct gccaaacaat tctacgtcga
    35461 ggggctcggg tgtgtcctgg ggcgggaatc tccaacggcc gtcaccttcg gcctcgccgg
    35521 gcatcaactc gtcgcccacc tctctgaaga cgaactcgat cggcagaagg gtatctatcc
    35581 tcgccatttc gggctggtgt tgacgcggga ggaagaatgg caggcgctgg ccgatcgcgc
    35641 ggaggcccag catcttacgt tttatcaaca gccacgccgc cggtttcccg ggacacgaat
    35701 cgagcatcgc acgtttttcc tggaagaccc gtcaggaaat ctgctcgaat ttaagtatta
    35761 cgtccacgag tcggcgattt tcggagagcg cgactacacg tcggtcggcc aatccacata
    35821 gtgctggcgt tgcgcgtgac gagtgaatgg tattactcca caggaacgac ttcgagactt
    35881 tccggaggga gtcggttgat cgaggccgct ttccggccgt tccctctctc cagccagcga
    35941 acgatgtggc gttgccgtcg agtgagatag gcggtgtgcc gaatcgggtc atagcgacga
    36001 ggggaaggaa gaatcgcggc cagcagggct gcctcctcga tcgtgagatc ctcggcggac
    36061 tttccgaaat ggtggcgcgc cgccgcttcc gctccaaaga cgccctggcc ccattcggcg
    36121 acattcaaat acagttcgag aatctgcttt ttcgtcagat ggtgttccag ggagcgggtg
    36181 atcaaggcct cccgggcttt ccgcagcaga gaccgttcgg atgacaggta gagatttttc
    36241 gccagctgct gcgtgatggt actgcccccg cgtttgaatt cgccgacctc cagattgtag
    36301 agcgccgcgt ccttgatgcc ttcccagtca aatccttcgt gcgcgaaaaa ggaggcgtct
    36361 tcagccgcga cgacagcacg ttggagcgcg ggcgaaatcc gggacagggg aacccaggcg
    36421 aatttgatgt gcagcggatg gccttgttcc ttggcttggg cccgccgggc ttccatcacc
    36481 gccgtttctg tggggtgatg tttcgccagc cgcgagacgt cgggcaatgt ggccagccaa
    36541 tacaacgcca aggcggcggc cggcaaaccg atgagcacgg tcatccaaaa cagtatccgc
    36601 ccgaagagac tgcctgttga cttgctcatt ccctacactc tatctatgag cctacgagat
    36661 ggctcacttg tcctctgtgg cccaagttgg cgcccatccc gcattgctgc ctgacgcgat
    36721 cattatgaaa ctactcagcg ccgagtttat caaaagttcc gtgtccccag aacagtttcc
    36781 tgccgatcac ctgccggaaa ttgcgttcgt gggacgatcg aatgtcggga agtcctcgct
    36841 gatcaattcg ctcttgcatc gcaagaaact ggcgaaggtc agcaagacgc cgggcaaaac
    36901 gcgcgccgtc aattttttta ccgttcgtac ttccgatccg aagctgccgc tcttgtcact
    36961 ggtcgatctg ccgggatatg gctatgccaa ggtctccaaa acgatgcgcg cgcaatgggg
    37021 cccgatgatc gaacaatatc tggaacagcg gcaatcgctc ggcgcggtga ttttgctgat
    37081 cgagtcgcgc gtctggatgc cgcaagatgt catgacgatc cagtgggtgc agtcgctggg
    37141 ttgtggcctc atcatcgtgc tgacgaaggc ggataagttg cgacagagcg agcggaaacc
    37201 gactctcacc gaagtgcgtg tcgcttgcgg gctgccggcg gaagtgccgg ttcttttgta
    37261 ttcggccgaa acccacgagg ggcgggacgc gttatggggc gagattcgcg cgcagtttaa
    37321 tggattgcag aaacacgaat ctggcacaag agaacttcga tagcacgctt gtatcacatc
    37381 gcaaaagaac actcccgcag gatgctcaaa aagaccgtcc agcaaggccg cagcgagtga
    37441 agggccgaag cgtacccttg gaggtacgtt gagggtctga acgaggcgag aacgctgctg
    37501 gcggactttt tcagcatcct gttaaaactt gatctcgatg taggccttgt ttttcagatc
    37561 ggccatccag atctgatatt ggtcttcggt cttctgctga aacacgaggg actggatttc
    37621 cgccttcact tgttcgaacg ggcgaaactg gcgcggcttt ttgtcatcga cgcgcacgat
    37681 atgcagcccc tcagccgttt ctacgattcc tgtaatctgc cccaccggca ccgaggtgag
    37741 cgcctgctcc agtgccggaa tcagttcccc ttgccggacc agtcctaacc gcccgccgcg
    37801 cgaagcgtct gcgccatcgg aaaaacgcag cgccagatct tcaaagggtt cgccttgttt
    37861 gagcgtcgca aggagggctt cggcccgacc ctgcgccacg gagaggccgt ccggtgtccg
    37921 cggtttgatg agaatttggc tcaactggta ttcctcgggg taggcgaaac gatcctggtg
    37981 ctcctcgtag taccgcttca tttccgaatc ggcgaccata atcagccctc gaacttcccg
    38041 gtcgacgaca cgcatcaacg tcagctgttc acgaacgctt ctggtggtgt tggggtctgc
    38101 ctggttgagg gcttcgccct gttttttcat ttcctgcacg gcctgcgtga cttcctggtc
    38161 ggacacctcc acgcccttgt tcttcgcggc ctggagctgc agcttgcgct cgatcatctt
    38221 cgtgacggcc atcgcttccg cggtcttgag gcggcgttcg agatcctcgc cgctgtacag
    38281 cttgcgaagg cgctcctgat cgggaagcaa gtcgcgcttg agctcggaga gcatgatcag
    38341 gtcggtattc acgactgcga caatacggtc ttccaacttc gcggcatcga ccggaccggc
    38401 cgggaacagc cctacccaga cgtaaaggca taggccggcc aaagccggtc ggctgagcga
    38461 ttgcagagag gttggtctca cggcgcggac acaatgagaa aggaaagaca atcgggcatt
    38521 catcacggta aggggattgt acacaatcga gacttcagaa agggagcgat cttgcgatga
    38581 aaaggaagga ggcgtgaaca cggaacgcgg gcaggaagcc gttgcgcagg aggttagggg
    38641 cgccctggtt catcggtcac ataacgggcc gcatcagcca tgcgaatcgt cgcaccggtg
    38701 cggagttcgg caaagacatc atcaaggcgt ttccgccgct tctcagccag gagttcctgg
    38761 cgaagccgtt cacgggtggc ctggtcggcc tgtaaaattt ccggctccag gggactgacc
    38821 ttcatcagat agtaaccctt gtcggtcttg atcggatcgc tgaggacgcc ggggtgcagc
    38881 gacggaatca acgcgtccag ttcaggctcc agcaggccct ttcgataggg gccgaggtcg
    38941 ccgcctttgg cgcggctgcg ttcgtcgatc gaatagcgca gggcaaagcg ggtgaagttc
    39001 ccgccgcctt ccacctggcg cttcagatcc ttggccgcat agacgttggg tagcaacatg
    39061 accgaaacct gaactttggg attcgccagg agctggttgg catgcttttc gaggtaggca
    39121 tccaattctt ctttggacac ttcaaccttg gtcttgatcc ggtctttcag gagttcatcg
    39181 agaatcagct gctcgcgata gcgcagggtt ttctcccgga tgtcatccga ttggtccaag
    39241 ccctgtttgc gcgcttcctg catcaacagc tcgcgcatga tcaattcatc gaggaagcgg
    39301 cgtttcccgc cttctttttc ataccgggcg cgggtggcct gggagagttc ttcccaccgg
    39361 atgtcaaact cagcttgggt aatggagcgg ccgttgatca tcgcgatcac cggttcctcc
    39421 tgcggcggtt cggtacagcc ggccaatgag cccagcgcac acaaggctag cgcggtgccg
    39481 gtcagtcgtg cccgccaggg ggatatgtct ggtgtctgcg gtgatgtcat gcggtcgggg
    39541 cggagcatcc ttctgggaag atcaggtaga gccggtccgt ggctcttgat tgttggtacc
    39601 acagacgtga agggtttgca aggttgcgtt gagttctgga aagaccaaac tccagtcgtc
    39661 atgcggcatc tggagttcaa acgacaaagg cgacagaaat cgcagccgtt ttttataccg
    39721 gtccatcagg gcctgcacag cggtttccga aactttcgcc ttgggatcga aggtgatcac
    39781 gaccgcatgc gtctgctcga ccaccgaact gagccggagt tgtttggcca ggagccggat
    39841 ctgcatgagt tcgaacagtc gttcgactgg gtccggcgga ggcccatacc ggtcttcaat
    39901 ttcgccatgc atgagcgcga ggtcgccgag ttgtccgcag gaggacaacc gtttgtagag
    39961 cgagaggcgt tgatggctgt cgaccacgta gtcttccgga atgtaggccg agacgctgag
    40021 acgcagtgta gggtccggct cctcctcgac gacctggccc ctcaggcgct ggacggcttg
    40081 ttccaccatt tgcaggtaga gatcgagtcc gacggcggca atgtgcccgg attgttgttt
    40141 gccgagcaga ttccccgctc cgcggatctc caggtccgcc gctgcaatcc ggaatcccga
    40201 ccctaactcg gtaaattgct ggatggcggt cagccgcttc tgcgcgtcgt ccgagagatt
    40261 gccttcatcc ggcaccagga aataggcgta ggcctgttca ccaccacgtc ccacccggcc
    40321 gcgcagctgg tacagctggg ccagcccgaa cgcatccgcg cgattgacga tgatcgtgtt
    40381 ggcggtcggc acgtcgatgc cggattggat aatcgccgac gcgatcagga tatcggcttc
    40441 acggtggaaa aatttcagca tcacggcttc caggggtttg gaatccatct ggccgtgtgc
    40501 catcacaatg cgagcctcag ggaccagttc ctggagccac gcgcccattc gttccatggt
    40561 ttccacgcga ttgtggacga agtaggtttg tccaccccgg ccgagctcgc ggagaatcgc
    40621 ttcgcggatc gctttttcgc tgaaccgaag cacttgggtg cgaatcgcaa ggcgcccgga
    40681 cgggggcgtg tcgatgatgg acaggtcgcg cacgctggcc atggtcattt gcagggtgcg
    40741 cgggattggc gtggcggtga gcgtcaacac gtcgacctgg gtacgcagct gtttcaagcg
    40801 ttccttatgt ttgacgccga accattgttc ctcgtcgatg atcacgaggc cgaggttgcg
    40861 aaactgcaca tccttttgca agagccggtg ggtgccgatg agcacatcga ccagacccgc
    40921 cgccgtatcc ttgatgatgg ccttcgtgtc tttgggcgat tgaaagcggg acaacagcgc
    40981 cacgcgggtg gggaagggcg cgaaccgttc ggcgaaattg tcgtaatgtt gatgggcaag
    41041 cagcgtggtc gggaccagca cggccacctg ccggttttct tcgacggcct tgaaggcggc
    41101 ccgcatcgcc acttccgttt tgccatagcc cacatccccg cagacgaggc ggtccatcgg
    41161 tttggtggag gccagatctt tcgcaatatc ttcgatggcc ttccgctgat ccggggtttc
    41221 ctcatattcg aaggccgcct caaactcgtg atacagcatg ctgtccttgc cgtacgacgt
    41281 ccgatggacc agctcgcggt tggcgtagag atcgacgagc tcatgggcca tttcttcgat
    41341 atcttttttg actcgcgccg tcgtttttgc ccaactcgtc ccgccgagcc ggtcgaggcg
    41401 cggcacatgc gcgtcggccc ctgcatagcg ctgcacctgg ctcagccggt cgagcggaac
    41461 atagagctta tcggtcccgg cgaactcgag caccagaaag tcactgtcga agtcctggac
    41521 cgagagccgg cgcaatccct gatatttcgc gatgccgtac tgcatgtgga cgacgaaatc
    41581 gccgatgttc agatcttcga gcgaagagag aaacgtggcc gctttgctct tgtgttgcgg
    41641 tttgtgccgg gcaccctttg cgaacagttc ttcttcggtc agcacgacga gccgcaagtc
    41701 gggcgaaagg aatcccgaag acacctcgcc gttcaggacc gaaaatgggg ccttctgcgc
    41761 gccgcctgct gagagggctg cgggtttcca ctccatcgcc ggtcgatcgt gctcgccgaa
    41821 gagcgcgagc agccggccga cttggccctg actccgggcg accagcacca cgggcccgcc
    41881 ttcacgcagg cgatcgagga cttccagtgt ctgactaaac gccgtgccgc gctggccgag
    41941 tcccacgctg gccggtgttt gcgccggaca ggtcagtacc ggttcccagc tcgcatccgg
    42001 cgcggtgacc ggctccaggg cgagggtcgc atacccctgg gtcgcggtga cgagttgatc
    42061 ccacgtgaag tacagctgat ccggagtcgg atagggattc ggatccgtgc gatcttcgtg
    42121 acgcaggtac ccttcctcaa tggtctgcca acattctgcc gtgtgagctt tgagggcgcc
    42181 gggctgatcc agtaccagca cgggcggctg gggaaaataa tccagcaggc tgtccatcgc
    42241 cccatagacc gacggggcat gccattccgc atctgccgcc aggggcgcaa gcgcgtctgg
    42301 tgaatcgtcg gggcggatca gttctcgcgc gggcaggacc caggcctgct tgatcttatc
    42361 ggtcgatttt tgcgtggccg gatcaaaaaa gcggatcgat tcgatcgtat cgcccaaaaa
    42421 ctccactcgc agcgggtccg gataggccgt cgaataaatg tcgacgatgc ctccacgaat
    42481 actgaattcg cccgggatct ctaccactga tcccttgcga tagccgaggc gcaacaggct
    42541 cgagaccagc acttcgcgct ccagatcgct gttcggttga aactgcagta tggattcggt
    42601 gaagaccagg gctggaagca cacgttgcgt cagagccggc acggacgtaa agagcaccgt
    42661 gcgagctgtg gtgcagagtc gattgagcgt ttgcatgcgg cgggagacga ggtcgatgtg
    42721 gggcaccgtc gattcgtagg gcagcgtttc ccatttcggg aacagggcca ggtcatcgcc
    42781 tgattggccg cagagggttc tgaaaaaaag cgtgtcgcga tagagccgct ccgcttcgtc
    42841 atccgttttg gcgacaacca gccacgagcg gtcggcgaga ggttgtgccg gcgcgctgag
    42901 cgtgaggagc gcgagcccga agcctgccgt ggagccgtgc aatcccatca agcagggttt
    42961 gcccgatccc gtgcggaggg cctctcgcgc aggcgcgaac cagttcgtga gatgcgatgg
    43021 gacgacaggt ggcacgaaat ccttatgccg tggtggagcg aatacgttgt accagggtcg
    43081 tggttgagac gccggggacc agaggaatgg tttgcacgcg cccgccgcgt gcctcgacgg
    43141 tttcacggcc gatgatccgg tcaagcggcc agtctccccc cttcaccaga atatccggct
    43201 gcagcgctgc gatcagggct ccgggatccg gctccgaaaa gatgaccaca taatcgacac
    43261 aggccagtgc ggcgaggacc tcggcccgtt ggacgtccgg gacaatgggg cgatcgggac
    43321 ctttgctcaa tgcgcgcacc gaaccgtcgg agttcacgcc gaccacgagc agatctccca
    43381 gattgcgggc tgcctgcagg taccggacat gtccgatgtg catgagatcg aaacacccgt
    43441 ttgtaaagac gacgcgctgt tgccgctggc ggcgctcggc cagcagagaa accagttcat
    43501 ctcgcgtggt cacttttgta ggcatcacgt tcaatcaatc ctcgcgtgca tcttatcagg
    43561 atggagaaaa agtctgccac caggaatgca tggcgaacgt ggtgcgctcg ggaatcagtc
    43621 tggcgtgcga ggtcttcgtt tcctcgtccc agcttcactc tgcgggaggg cgcccagacg
    43681 cacgacgccg gtcccatgtc gttcgatcag tcgatccagg gcggcaaccg catcgcgttg
    43741 acggcggtcg aacagcggtt ccggagccgg taccagatcc gataggccca ggcccaccag
    43801 gcggtaccgc aatcgcggct gaagcaaatc tcccaaggcc tggcgaatct ccggccacat
    43861 gtccgggtca tagttcaacg gcgtggcaaa cttccgttgc cgcg
//
LOCUS       DAOQPD010000024        43854 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_340_length_43854_cov_19.531473, whole genome shotgun sequence.
ACCESSION   DAOQPD010000024 DAOQPD010000000
VERSION     DAOQPD010000024.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 43854)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 43854)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43854
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_340_length_43854_cov_19.531473"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            597..1535
                     /locus_tag="PK063_07800"
     CDS             597..1535
                     /locus_tag="PK063_07800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016292066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthase"
                     /protein_id="HMZ96990.1"
                     /translation="MEKQARIFVAGHQGMVGSAILRALTSRGYERLIVRASGELDLRD
                     NVRVAAFFEEVKPDYVFLAAAKVGGILANSTLPAEFIYDNLAIQTNVVHQAYVHGVKK
                     LLLLGSSCIYPRDSPQPMKEDYLLTGPLEPTNEGYAVAKIAGIKMCQAYRQQYGCDFI
                     VAVPTNLYGPNDNFDLQHSHVLAALLRRFNEAREQGGEPTLWGSGTPLREFMHADDCA
                     DACLFLMERYSHAEIVNVGAGEGISIGRLATLVAEVVGYRGDIHWDPTKPDGMPRKLM
                     DCGRMKALGWTPRIPLREGLQDAHRWYQGHVKRIAD"
     gene            1829..2947
                     /locus_tag="PK063_07805"
     CDS             1829..2947
                     /locus_tag="PK063_07805"
                     /inference="COORDINATES: protein motif:HMM:NF015983.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HMZ96991.1"
                     /translation="MTSKPLVVVPDEKTYGLKPGAEEFPLMVIISIIYPCNMGCPNCP
                     YTDTNSELRRFYHEHDGDLIPVKLWEKIADECGPYGAWMRCTGGGEPMLHPKMVEMIE
                     YAKAKGARVWLNTNGSMFGPNAKHRERLERVIRAGIDLIEFSMDAADAETYSVLRPPR
                     SGKTGDPEQWWTKHVGNVRAALDLRKQHVATTRVVTSIIRQEAIEGRLDDAVQFWLKD
                     VGVDEVITRKFLSWDDNTTIQLGKTLDRHLYADLPKQKKEPCVWPFERLNVDTLGRIA
                     LCGQDISFKTSELFPNVKDTSIKEIWQGEMFTWYRRMHLEGRGAECFPCRGCSAWFAG
                     IRDWDHGWQKVLRNSGDHLKEVMRRDLGVEVEVFQPKV"
     gene            2976..3935
                     /locus_tag="PK063_07810"
     CDS             2976..3935
                     /locus_tag="PK063_07810"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: protein motif:HMM:NF012760.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HMZ96992.1"
                     /translation="MSEKNVVQNKAEAHRGRVIVFGYGALAAAAVTALLSAGAEVIAV
                     VAPSNRSGDDVDFIKDFACTAGIPVLVQPPRKTIAPFVQDLKRLDPDVIVVWSYPMIL
                     PPDVIEVPREGTVNVHGGLLPEYRGGHVMQWAIINGESETGVALHYMDEGIDTGPVIA
                     QRRFPIERDDDAATVREKLKEAGMALLKEWWPAISQGRAPREKQDEATAKYHRLRTID
                     DGLINWHASATEVCNLVRALVRPWPGAFTILNKKKLVIWKCRLLVQETSGVPGLVVQV
                     DAQGARVCTRDRDVLIETAELDGERMTGLDLKRIMQAGTCLGA"
     gene            3959..4393
                     /locus_tag="PK063_07815"
     CDS             3959..4393
                     /locus_tag="PK063_07815"
                     /inference="COORDINATES: protein motif:HMM:NF016056.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF393 domain-containing protein"
                     /protein_id="HMZ96993.1"
                     /translation="MSMKERVYVIYDGQCRFCIRSLKLFSAADIFKVFRFYDAHDEQS
                     VAALFPELQGADFDNAMFVVTERREVYRGFFAFRRMIWSSPLLWPLIPVFYFPGATPV
                     GTRLYAWVAKNRLKFGCQSDACTLPARLPKDPSSDHVDVVPH"
     gene            4465..5958
                     /locus_tag="PK063_07820"
     CDS             4465..5958
                     /locus_tag="PK063_07820"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ96994.1"
                     /translation="MEMFFAPQGFLHPELSLSVQMFMRVVYGMLLCGMLLLAIPNWRR
                     FFLSERWGGYAQSLREVEFIQNPLVFPLVMAVWFACGVCITGGWWTPWPALLNLVLCR
                     YFFVGMRWKGLLRGMGAPGYILYWGGLAITVLEYTLHYAPELRSLALQVLQADFACVY
                     ISSGVYKLSAGYAKNHGMELGMTNPAWGYWWKHYQHFSPSHPLFRFLNHLAWSSQIIA
                     GILMLLPPTRFIGGMIIFGMFAFIATQIRLGLLCEIVMFCSSLIFLHPGSLGDIVVTA
                     VVGQVQSPSVASFAFSSVANTVLGWALAIYLILLPFAHVGLSYNFYLRRSLPKPLQMA
                     LERYTNFFGLIVWRVFSVDIVNFFIRIYHYPKAHESDRQLISDESVGARLRFGHVAES
                     IVLACIFTTLKYYPHNSGLFHERLLRYARTFPCEKGELLIFEYLSLRKEPDRFVFAPV
                     AEYTVDTAAMTVVERVIDPSVSVRAPHAVSPVHEGVRPGTYAPAGGR"
     gene            5964..7820
                     /gene="asnB"
                     /locus_tag="PK063_07825"
     CDS             5964..7820
                     /gene="asnB"
                     /locus_tag="PK063_07825"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: protein motif:HMM:TIGR01536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HMZ96995.1"
                     /translation="MCGIAGRFGPGPNQAVKKMVALLAHRGPDDEHVVSGRNFAIGAR
                     RLSILDLQGGRQPISNERETIWAAQNGEIYNFPALRNELLERAHVLKTHCDTEVLPHL
                     YEEHGAAFPKKIDGMFAVALWDGDGQVGYLARDRTGKKPLYYCLHDQALYFASEIKSL
                     LQIPGFTRRLNLDALHQFLSLKHVPHPLSIFEGIAMLPPAHMLTYRAGQEPVVSRYWD
                     LSFAGSDTSAGMTEEEITDRLLVLLRQGVERRLLSDVPIGFFLSGGIDSSLSTVLAAE
                     LSPSKIKSFTLTYSRESTTEGKEEDRRWARWVAEQYGTEHHEETIQVSSFPENLRRIL
                     TCFDEPYAGVVSTYFLAQLMSQHVKVALSGDGADELFGSYLSHRLAVPLANFQTYLQT
                     GNSALIRPFEQQVDFLARMADPQDWGWRYKLLVFSDEEKDALYSEEIASHMRSYSTRD
                     RLRHDFSELSARDPLNRILESEFRTIFPDQVLAFVDRLSMAHSLEVRTAFLDTDFVEF
                     VAGLPGSLKIKDGETKYLLKKLGLRYFPREMVYRKKEGFLMPITQWLLRDLESYVRET
                     LSPERLAKHGLFRAAYVQRLVDALYQAQPDHLAVNKVYALVVFQEWYDLYMV"
     gene            7872..8582
                     /locus_tag="PK063_07830"
     CDS             7872..8582
                     /locus_tag="PK063_07830"
                     /inference="COORDINATES: protein motif:HMM:NF020463.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WbqC family protein"
                     /protein_id="HMZ96996.1"
                     /translation="MHDPNLQSSITLCVLQPGYLPWLGFFDQMRRSDIFVLYDDVQYD
                     KHGWRNRNRIKTPKGPHWLTVPVRHKGLGWPRINEVEIDNQTVWGKKHIGTIRQFYAK
                     APYLAQYLPMLEDRLLRPWTLLVDLDLSLIDLMCEWLQLKRDVIRASSLGIEGDRSDR
                     LLALCRHFGATRYLSGDAAKTYLDRELFAQNGIEVEWQGFQHPVYPQQHGEFVPFLSA
                     LDLVLNCGPDSAAILRGQ"
     gene            8596..9630
                     /locus_tag="PK063_07835"
     CDS             8596..9630
                     /locus_tag="PK063_07835"
                     /inference="COORDINATES: protein motif:HMM:NF027681.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HMZ96997.1"
                     /translation="MKTILITGGAGFIGSNFVRYLYDKYPNYRLIVLDALTYAGNVKN
                     LPVDINNGSDERLMFWYGNVRNAELVDTVVSQSDVVMHFAAESHVTRSIYDNLLFFET
                     DVLGTQAVANAVLKYRDKVERFIHISTSEVYGTAESEKMSEEHPLLPMSPYASAKCGA
                     DRLVYSYWQTYGIPAIIVRPFNNYGPYQHLEKVVPRFITSCILDEPITVHGDGSAARD
                     FIYVQDHCEALDLILHAEPKRVFGEVLNLGTGRHISLMEIADTVRALMKPKKSPIQFI
                     GDRPGQVFRHTCDHSKVSRILGWQPRTSFEQGLERTIQWYRENEAWWRPQMWMRRIPI
                     VTAAGKRELH"
     gene            9632..10765
                     /locus_tag="PK063_07840"
     CDS             9632..10765
                     /locus_tag="PK063_07840"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF013227.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HMZ96998.1"
                     /translation="MGIPFYRHDLGEPEVEAVRKVLAGPILTTGEVVESFERRFAAYL
                     GVPHALAVTSCTGALHLSLLALGIGLGDEVITTPMTFIASSTAILEAGAKPVFVDVES
                     QTGNLDATKVEAAITPRTKAILPVHLYGQMCDMVTIRKIADQHGLFVIEDAAHCLEGV
                     RDGVKPGELGDTACFSFYATKNLTCGEGGALVTKDRGLAEKLRLLRLHGMTKTAADRH
                     REGYQHWDMTVLGWKYNMDNIHAALLLPQMDRIEQNWSKRDTVARWYEGLLSDCPGVS
                     VPKSHPQVRHARHLFPVFVEGGGRDAIIQGLQEDGIGSVVNYRAIHLLSYFRDTFGFR
                     VGDFPHAEKIGDSVVSLPFYPAMTENQVTQVTATVTRLLKARR"
     gene            10881..12203
                     /locus_tag="PK063_07845"
     CDS             10881..12203
                     /locus_tag="PK063_07845"
                     /inference="COORDINATES: protein motif:HMM:NF014051.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HMZ96999.1"
                     /translation="MSTLKLSLVGLGARVILLVINVISVVLLARYLEPQGRGEYFLFQ
                     TLVSVLSVVGDCGLSQSANVFVGRSAHRKKLIHAFVSKAAIILWIGMSGIGGLVLWMA
                     GEQLLHDFPARWQWAAFAILPCMLYAGFWNSLMIGLGEIPLLNGVQLVIGPVQLILIL
                     VLVVGFSGGVASAVTIYLSTMVLQCVLMVALSRRLGFLGGSEYVEAGLSRQMLAFGLR
                     AYPNAIATMGWMRIPVFVLNAFHGAASVGIFSVAQQLAERALMPIQAAQDAIYGKMSA
                     LSPREAIAAMNRYIRIVVSGMVASTVGAMLLAPWIVMALFGPSYQPAVYVFWILLVGV
                     VFVSVSMIVSTYVLGQRGRPGLLSLLAGANACICLASSYWLIPTWAEMGAAMALALTQ
                     AVGAVVVFGLYWITSSATLRETLLLTSEDVTSVLKQLGKLTWRKGTQS"
     gene            12179..13441
                     /locus_tag="PK063_07850"
     CDS             12179..13441
                     /locus_tag="PK063_07850"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HMZ97000.1"
                     /translation="MAEGHAELTSADPISVVHLIDGLGGGGSERWVWDIVRLSEPTLC
                     KHFVISFFPDNAKFVYSEPLRSRGAYKQPAHHPFLEWLERGIQTVASQWYLLPIRKTL
                     SGLWWFCNAVDVWWRVAVALVQKRPDVIHVHTFHGLRVGLVLRRMLQIPLVHSVPALF
                     SQMTDAGFHGIPQLYRSNQQWVARFITGASVAELHSIGIPDSKIMPIHGTVDLTSSTS
                     MRKQKQHYYTALRDELKLPGDAVIALSVGRLHPSKGHAFALEAVPELVAQFPQLHWVV
                     LGEGEQREALEARASELKVREHVHLLGFQRDPLPYYAAADIYLRTPVFESENLSSYQA
                     MAMGLPVVGFDTGCETELLGKSGHGVLVPARNSEALAKAVVEMLSLPDRGARIGLRGV
                     EYCRQHLDIDRTISDLVRLYQHLGAKRA"
     gene            13499..14593
                     /locus_tag="PK063_07855"
     CDS             13499..14593
                     /locus_tag="PK063_07855"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024831.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HMZ97001.1"
                     /translation="MKVTFVISALFAGGAERVISIMANYWARKGWGVTILSFDDGETP
                     PFFEVDPSVRRMSLGLLGDSAGLIAGIRNNINRVVRLRQAILRSQPDAVISFVDKTNV
                     LTLFATLGLKLEVMVSERTNPYQYSIGRIWGALRWWVYSRADRIIVQTHAARAYFLPK
                     FQRTVSVIPNPVLPSSSNYAMVNHRPAGCMILAMGRLSKEKGFDDLLYAFRKVNDQHP
                     GCTLTIIGEGPERGELELLCERLGLSGCVLLPGLVTTIEVFLRQASMFVLSSRFEGFP
                     NALCEAMAYGLPVIATDCRSGPREIIRDGEDGLLVPPGDRDALATAMDSLMSDPERRA
                     RLGGRAMDITQRFGVEKVMGMWEKILEPIA"
     gene            14607..15449
                     /locus_tag="PK063_07860"
     CDS             14607..15449
                     /locus_tag="PK063_07860"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF024880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HMZ97002.1"
                     /translation="MMTQQAQEVADGRRFEFGQNWRRFLEDLTEERIGRAQESLQAML
                     GLKSLAGQRFLDIGSGSGLFSLAAKRLGASVRSFDYDPHSAACTAELKRRYFRDDDTW
                     IVEEGSILDMAYVQSLGTYDIVYSWGVLHHTGAMWQALDNASRLVADQGTLFIAIYND
                     QGGASRRWLMVKRVYNRSPQWGKILVAWLACIRQWTLTVVRDTFLGNPLRTWFSYKEQ
                     RGMSPWRDVIDWVGGYPFEVAKPEEIFDFYRKKGFDLQRMKTCAGGIGCNEFVFHRVS
                     TERL"
     gene            15446..16570
                     /locus_tag="PK063_07865"
     CDS             15446..16570
                     /locus_tag="PK063_07865"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024831.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HMZ97003.1"
                     /translation="MKVRFLIRSLQRGGAERQCVALAKGLRQLGHDVGVLVFYSGGDL
                     YDELLAAGIPVESVGKLRRWELVGFLQRIRRCLRRERPDVVYSLLQVSNVVAAVEKLF
                     VPTLRVTWGIRTASMDLTHYDRLVRVSYWLEARLSRFADHIIVNSEAGLRYAKVEGYR
                     TDRISVIPNGIDTELFAPDRSKGKTVRCSWGIRDEEVLIGLVGRLDPIKDHPTFLRAA
                     ALVVRQCALVKFVCIGGGDSAYKESMVALCAELALSARVIWAGEHSDMPAVYNALDVA
                     CLTSTAEGCPNTLLEAMACGVPCVATDVGDSKRILGEIGGIVPSRNSEALAGAIQELL
                     RMDGAERAKQGQMGRDRVIQHFSLDRLIGDTASVLEATAR"
     gene            16737..17882
                     /locus_tag="PK063_07870"
     CDS             16737..17882
                     /locus_tag="PK063_07870"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024831.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HMZ97004.1"
                     /translation="MIRIIHVISGLDTGGAEVMLVKVLQGLDRTRFTNIVISLTDRGQ
                     LGEQIEASGIALHTLGMKRGCPNLSALVRLRRLFTTLQPAIVQSWLYHADLLSTLAVK
                     VSGSPILIWNLRCSHMDLTGYSRLTRIVQWMLVWLSHVPVAVIANSVAGRQQHARLGY
                     RPRRWVVIPNGFDLQRFRPDRSARAAIRTEWGLSDDTVLVAFIARVDPMKDHATFLDA
                     AKRVVDAKKKAHFVLVGKDTETLAPSVAKRGLTDHVLLLGHHGHIERLLPGVDVGCLS
                     SLGEGFPNVLGEAMACGIPCISTDVGDARDIIGDTGLVVPLRDPAALAGAMTDLIDRG
                     PAGRAKLGYAARARIEAEYALPKVAECYEVLYTELAAQSRSPRERMC"
     gene            17921..19894
                     /gene="asnB"
                     /locus_tag="PK063_07875"
     CDS             17921..19894
                     /gene="asnB"
                     /locus_tag="PK063_07875"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HMZ97005.1"
                     /translation="MCGIAGLLSQSRGELDATVARMVAAIRYRGPDDSGIWSDPAAGV
                     GLGHARLSILDLSPEGHQPMSSRSGRYVLSYNGEVYNFGELRTEFEAAGTTFRGHSDT
                     EVMLAAFDAWGIEMSVKRFVGMFAFAVWDNHTQTLTLGRDRLGEKPLYYGWQGQTFLF
                     GSELKSLKAHPAFRAEIDRDALALLLRHNYIPAPYSIYQGISKLVPGCLLTVSLSQRT
                     PQTKAFWSSRQCVEAGLAHPFEGSEAEAMSRLEALLKEAIGRQMVADVPLGAFLSGGI
                     DSSTVVALMQAQSSRPVKTFTIGFHEEGYDEATHAKLVARHLGTEHTELYVLPKEAMD
                     VIPRLPTLYDEPFSDSSQIPTCLVSELARRHVTVSLSGDGADELFGGYNRYFWATTIW
                     RRIGWAPQSIRTALAGALTALPPSAWNSVFQRFARFLPEGWRYANPGDKLHKLAETLA
                     VATPEEIYFDLLSHWKHPAEVVRGAHEPPTVLTDQTQWANLPDFERRMMYLDQMTYLP
                     GDILTKVDRAAMGVSLETRVPFLDHRVVEFAWSLPLSMKIRDGQGKWLLRQMLYRHVP
                     KALIDRPKMGFGVPIDVWLRGPLKGWAEELLDESRLQREGYFDPQAIRTKWLEHLTGR
                     RNWAYYLWDVLSFQAWLESMGDSAHNGAHILAQ"
     gene            19884..21578
                     /locus_tag="PK063_07880"
     CDS             19884..21578
                     /locus_tag="PK063_07880"
                     /inference="COORDINATES: protein motif:HMM:NF015651.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysylphosphatidylglycerol synthase transmembrane
                     domain-containing protein"
                     /protein_id="HMZ97006.1"
                     /translation="MLSNFSFRRLPAVFVSIFLIAFVLWSAGVEDVLRRLAGFPPWAV
                     ASMLALLTANLFVVSFRFWRVLAHFGIALPWDIALRASIAGTVAGLFVIPLFGQIMGR
                     QGVLNSFGVQPVVNASLAAYERALLALLSGVLGTLGAVYLLGRSAVSDFFNQIALPEI
                     VVAAIGGWALSLWLGGSRFERKLSRRTLSWTNLEHVMSIAGLTLTGQLLMLACFVVGI
                     LAVSQDIPIASLFAASALISLAASMPITVGGWGVREVAAVYVFGLLGIPAADALAMSV
                     MVGLCSTLVILASSPFCFRNSLMSDLPKPPAVMIHSVSEIEEFTAWVLGTVVAVAVFF
                     QVHVSLSGGPINLNLADPFAILALAAVSLHALFARQFPVWRVPQFNFALCVISLLLLV
                     GFVHGWLEIGITQWALGGRLLGWLVLLGYLSSGYVIVANVGTHGLRRFAETLIATAVV
                     VVMLQVALRLLSHWGVNAAAQLTQNFEGYAGNRNAFALQVLAGMALFLGYSHLYARHN
                     IRVPRSVRPWIFSLLLGILLAGLVWTGSRTAMLVGAMALVLAWLGGMADHKMLGWG"
     gene            21575..22048
                     /locus_tag="PK063_07885"
     CDS             21575..22048
                     /locus_tag="PK063_07885"
                     /inference="COORDINATES: protein motif:HMM:NF016800.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HMZ97007.1"
                     /translation="MIFAALLWSIVLLVPQKYGNMSVQSKLSYESSNLERWETLTHGL
                     EMWQQSPVLGVGLGVFNEKSPMWAGHPQVIHSTPLWILAEFGLLGGAVFGWTFFLLAH
                     HAIRSGTTQPANCILLLLLVAFAVFSLAHEIFYQRILWLVLGAVLTRPYAHRRHA"
     gene            22045..23166
                     /locus_tag="PK063_07890"
     CDS             22045..23166
                     /locus_tag="PK063_07890"
                     /inference="COORDINATES: protein motif:HMM:NF012744.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HMZ97008.1"
                     /translation="MSRCPKLLFVVTEDWYFVSHRLPLALAAQKAGFDVVVATREGEH
                     GERIRAEGIRLIPCHLSRRRGNPLQEIAMLARLYRRERPDIVHHVALKPVLYGALAAK
                     IAAVPHVVNAVAGLGWLFTSNTLAVKALRPAFCRLLVWLLGASSSCTIVQNPDDFGLL
                     TQKGVPEDRLRLIRGAGVDTEVFAPPSQLPSEPVTVVFAARMLLDKGVREFVEAAHVL
                     TDAGVKARFVLVGDPDPGNPASVPDTSLRAWHGQHGIEWWGRREDMPAVLQLGHIACL
                     PSYREGLPKVLLEAAACGLPLVTTDAPGCRDVVHDGDNGFLVPIRNAQALALALARLI
                     EDAALRATMGRRAREIVLAEFSQERIIKETLAVYLELTP"
     gene            23163..24110
                     /locus_tag="PK063_07895"
     CDS             23163..24110
                     /locus_tag="PK063_07895"
                     /inference="COORDINATES: protein motif:HMM:NF027681.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HMZ97009.1"
                     /translation="MNVLVTGASGFVGHAVCAQLVAQGVTVTAAVRRPAAQPVRGLAY
                     CQVRDLGPDTDWHEALTGVHVIVHCAARVHVMQETDADPLPAFRTANVCGTVALARQA
                     AELGVERLIYVSSVKVNGEGGQDAYRETDVPAPQDAYGVSKYEAEVGLREIAAHTALK
                     VVVVRPPLVYGPGVRANFQLLMQALARGIPLPLGAIRNRRSLVGLGNLVDFIVTCIEH
                     PRAANEIFFVSDGEDLSTTELIDRLALAMNRPARLIPVPMPALRSGLTLLGQREMAAR
                     LCGNLRVNITKARTLLGWCPPIRVDEELRRAAEYYLQHQ"
     gene            24143..25222
                     /locus_tag="PK063_07900"
     CDS             24143..25222
                     /locus_tag="PK063_07900"
                     /inference="COORDINATES: protein motif:HMM:NF013146.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HMZ97010.1"
                     /translation="MALLGVGGLVLVLTYWGIGWLCMPGSRLYLLDYPNARSLHEIPT
                     PRTGGLALLVSAAIGLIVATLWEFPTQAWWLSASQTSPTAGAWILAMTVLLAVVSFWD
                     DRDGLPVLLRLAVQLIAAATVVIGAGVSLSSLSLPAVGSLSFEGVAVPLTLLFVLWMT
                     NLYNFMDGMDGFAGGMTVFGFGAIAYFAWQAQHPFILILSLIISMGAVGFLLYNLPPA
                     RIFMGDVGSISLGFLSGTLSVLGVQDGLFDIWTPLLVFSPFVLDATTTMLGRAVRGEK
                     IWEAHRTHYYQRLVLHGWGHRKTLLSEYALMALCVAAAVLYHGATDSGRLAILVVWIL
                     GFAGLAVGVGLMEQRAGQQGRMYED"
     gene            25212..26534
                     /locus_tag="PK063_07905"
     CDS             25212..26534
                     /locus_tag="PK063_07905"
                     /inference="COORDINATES: protein motif:HMM:NF016800.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HMZ97011.1"
                     /translation="MKISRIPAVWASMEANHGPTLDLIVRALLYVYIFSLPFLPLLVV
                     ERNIFLVLLVLLPLWCLLRRRHFFVSSPVDLPLIAFVAWVAFTIPFSAHPAYSMKEFG
                     KLLQQVVIFYAVLYFFRERTARDLLTYLLLGCVLVVSAYGITQFQWYDGQATRSFFPA
                     EVWLTTYLVLLGPLFFSLAYYEVTNRLRYVYGCGSILVTICLLMTRSRAGLVALFVEL
                     WVMAWLLKRRSAVTVAGGATVVCLLAALFLIRVDTGSDGQLRLTLRDGTPVRTDGASV
                     IHRFDIWAFALSKIQEHWFVGIGYGKDNYKLVYGDEPEEVQPGHHPVKTAGAHNIVLA
                     SALHVGLIGMVLFLWLWGKLVRRLIQECHRTEGSTARAIVVGATVGVIGLGVRLMFDQ
                     MLVGTLAVQFWVVVGIAVLHVNSQRESDREGVVAAVSGAATLAGARSG"
     gene            26595..28490
                     /locus_tag="PK063_07910"
     CDS             26595..28490
                     /locus_tag="PK063_07910"
                     /inference="COORDINATES: protein motif:HMM:NF014740.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate sugar
                     epimerase/dehydratase"
                     /protein_id="HMZ97012.1"
                     /translation="MKRIAVQVFQKVSSRFGQTILAYRTALIICVQAGLILAANFTAF
                     AFRFDGQIPALYKDTMWRGMPLVCVVYLLGLWGFGIHRGLWRYVGLHDLGRIMWACVV
                     STIVTFVLLHPILGRVEYPRSVILGTGLLAGLNIAGIRLLVRWFREWLQIVGPTARRV
                     LIVGAGNAGELLVRNMQMNPAYNYRPVAFVDDDPVKQGAKIHGVPIAGCIQNIREIVR
                     RFEVHEILMAIPSAPLALKQKTLAAVEGAKVPIKILPSVRQLLEDPALLQQVRPMSLE
                     DLLQREPIQTDRQELHPLIEGKTALVTGAGGSIGSELCRQIARYRPATLVLFERYENA
                     LHALLLELQAAFPDVCILPIVADVTMPERVAEVFRQTQPDIVFHAAAHKHVPLMELNP
                     KEAVRNNVWGTRVVAEAALASRVDRFVLISTDKAVNPSSVMGATKRIAEHVIQGLSQL
                     GQTRFTVVRFGNVLGSNGSVVPLFAEQIRKGGPVTVTDREIKRFFMTIPEAVQLVLQA
                     SVMGQGGEVFVLDMGEQIKVADLARNMIVLSGFVPDKDIEIVYTGLRVGEKLYEELFE
                     AGEQVLATAHGKINRAVGAPLVAEGFERWIAELHSKLAESDEEELLHDLKRIVPTFQP
                     TSPLRVS"
     gene            28649..29116
                     /locus_tag="PK063_07915"
     CDS             28649..29116
                     /locus_tag="PK063_07915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HMZ97013.1"
                     /translation="MRLFATDVDGVLTDAGMYYSESGDEWKKFNTRDGMGIKLLQKAG
                     IVTAIITQESTKIVMRRAQKLTIPEVHQGAYDKLAVLKDLIARHGLTMKQVAYIGDDV
                     NDLQALGAVGFSASPADGMPPVLKVVRYVCKKNGGQGAVRELADLILAAQKSQ"
     gene            29165..30613
                     /locus_tag="PK063_07920"
     CDS             29165..30613
                     /locus_tag="PK063_07920"
                     /EC_number="2.7.7.13"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: protein motif:HMM:TIGR01479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate
                     guanylyltransferase/mannose-6-phosphate isomerase"
                     /protein_id="HMZ97014.1"
                     /translation="MTNHLYPVILAGGSGTRFWPLSRHLYPKQLLRIIGDETLIQQTM
                     RRVLSCASPDRVLISTNPGQADSIRVQLGEWKSDLKDNYVIEPIGRNTAPAIALVAAE
                     LLRRDPEAMMLVLPADHVVTGEKAFQAAVTLGMQLAEKGHLVTFGIKPTRPETGYGYI
                     QPNRRTTLAKKDRLTGHPVARFVEKPSRTKAAQYLKSGNYFWNSGMFLWKAATIRDEI
                     NRHQPQLAKAVQKVHTLMTSGADPRQIEAAYKKVPSVSIDNGVMELSSHAAMIPVGFG
                     WSDVGNWSSLEEVAPRDKAGNVVSGRVIDMDSSNSVLYADRRVVATIGLTDMVVVDTP
                     DATLICPKSRSQDVKQMVEILKQQGAPEHLEHVTVFRPWGSYTVLEEGPGYKVKRVTV
                     NPGGRLSLQLHHKRSEHWVVITGTARVTRGDDVLHLQIGQSTAIPVETPHRLENPGTE
                     TLHIIEVQNGPYLGEDDIVRFQDDYGRLGRAR"
     gene            30622..32022
                     /locus_tag="PK063_07925"
     CDS             30622..32022
                     /locus_tag="PK063_07925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HMZ97015.1"
                     /translation="MALFREYDLRGIVGEELTEPIAEQVGRAYATMAREQGASRISVG
                     RDGRLSSPALQQALLRGLLAGGLDVVDLGLCASPLLYFSLFTLPVHGGIMITGSHNAA
                     EYNGFKICIGKEAIHGEEIQQLRSIMERGRFSSGSGQLSSHPIIPDYLQHLKTVFAGV
                     RADHLHVVIDCGNGAASLVAKQALEQMGCRVTGLYDELDGRFPNHHPDPTVVENLQDL
                     IATVREHKADVGIGYDGDADRIGAIDERGEILWGDRLMIVYARDILAQRPGTTFISEV
                     KASQCLYDDIAAKGGRPIMWKTGHSLMKAKLKAESAVLAGEMSGHMFFADRYFGFDDA
                     IYASCRLVEILAKTKHSLSSLVADLPQTTVTPEIRVDCPDTVKFQLVEQVHRQLASYL
                     EAGQPVGASNLRMRELVTIDGVRAIFEDGWGLIRASNTQPALVLRFEAPSPARLDVIR
                     ATIETELAQARRVLSV"
     gene            32024..32836
                     /locus_tag="PK063_07930"
     CDS             32024..32836
                     /locus_tag="PK063_07930"
                     /inference="COORDINATES: protein motif:HMM:NF022750.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3108 domain-containing protein"
                     /protein_id="HMZ97016.1"
                     /translation="MTILRFPLSSTLLFVAAIVAGILLPSMLCAESTPDRRPSVSAPL
                     PFANGERLAYDVTWLGMRAGIATMIVQEGLDQRGRRQLTLSMTARSSPTVTKFYPVDN
                     RGVSQVDLDSFLPTHMTFARREGKRFNDFDYTFRHHEGLVTAVRDGKTDELQIPPDAQ
                     DAMSCLYYVRNVLPFVPGETLTMTVHHDKKNYKMDVRVEALETVEGRWGKAETARVVV
                     IMPFQGIFLNEGNIRVWFTTDPHRVPVRMKAKVVVGSIVAELTEGYGLAAQP"
     gene            32969..33961
                     /gene="fbp"
                     /locus_tag="PK063_07935"
     CDS             32969..33961
                     /gene="fbp"
                     /locus_tag="PK063_07935"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 fructose-bisphosphatase"
                     /protein_id="HMZ97017.1"
                     /translation="MAKFPITLSRFIIEQQAAHPEATGEFSVLLTQIGLVGKMIAHDL
                     RRAGLNKILGTTGETNVQGEIVKKLDQIANDTFVRVFEHSGLVCVLASEEMEKPLKMV
                     HEGAKYMLLVDPLDGSSNTDVNMPLGAIFSIRRSRTGQSVEDELLQKGTEQIAAGYVL
                     YGASTMLVFTVGQGVHGFTLEPSIGEYLLSNENIRIPSKGKVYSVNEGNYHRWPAGTQ
                     RYLDYLKVQDKPSGRPYSGRYSGCLVADVHRILLGGGIYLYPGEKDKPEGKLRLMYEG
                     NPLAMVVEQAGGKALTGTMRILDVEPKALHQRVPLIIGSAEDVSLAEDYVQGRA"
     gene            33998..34921
                     /locus_tag="PK063_07940"
     CDS             33998..34921
                     /locus_tag="PK063_07940"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fructose-bisphosphate aldolase"
                     /protein_id="HMZ97018.1"
                     /translation="MSNRVQEILSWYESDNAGTKTNIARLLNSGKLAGTGKLVILPVD
                     QGFEHGPARSFAPNPGGYDPHYHFQLAIDAGCNAYAAPLGFIEAGASHFAGRIPLILK
                     LNNHDVLHDEKDPLPSVTGSVQEALRLGCSAVGFTIYPGSSHCNPMYEQLRVIAEEAK
                     NAGLAVVVWSYPRGSGLSKEGETALDVVAYAAQIAAQLGAHIIKVKLPSAHLEQAAAK
                     KVYEAEKIPTATLTERVKHIVQSSFNGRRIVIFSGGAKSDEKTVFEEVRAIRDGGGFG
                     SIIGRNSFQRPKAEAVKFLNTIMSLYAGEKP"
     gene            34945..36495
                     /locus_tag="PK063_07945"
     CDS             34945..36495
                     /locus_tag="PK063_07945"
                     /inference="COORDINATES: protein motif:HMM:TIGR02037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegQ family serine endoprotease"
                     /protein_id="HMZ97019.1"
                     /translation="MDDGPIPPEQRQSMRSWIFPALLLSAGILIGIVLTSDLGWLPTG
                     HAVPEAPAVPAPVPRPVSTAVQPTLPGAGGQSFVDVAKIVKPAVVNIFATRNGGGEEG
                     KGTPFEDPFFRRFFGEEWMKRFEAPKERKQQGLGSGVIVDANGLIITNNHVVNKADEI
                     KVFLSDKREFKAKLVGTDAKTDVAVLKIEATGLPTVAWADSDKLEVGEFVLAVGNPFG
                     LTQTVTLGIVSALGRAAGIAEYEDFIQTDAAINPGNSGGALVNVRGELVGINTAIYSQ
                     SGGNMGIGFAVPSNMAHSIMDQLVQHGKVVRGWLGVSIQELTPELSSQFGVPKEVKGV
                     LVSDIMDDSPAKKAGFERGDVIVEYDGKPMDSPAHLRNAVAQTVVGKKVTVKLIREKK
                     PKSIDLVIAEQPKNLSQAAAEEGGESIAPAGLLADIEVREVNSELAGRYGLKSSDRGI
                     VVVRVKPGSQAEEAGVREGDLVLEVNRKSVGTLKSYEHVAANLPKDQAVLLLLKRQGR
                     AIYLTLRP"
     gene            36546..37568
                     /locus_tag="PK063_07950"
     CDS             36546..37568
                     /locus_tag="PK063_07950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAM domain-containing protein"
                     /protein_id="HMZ97020.1"
                     /translation="MVTRAIFVLLSALAGLALFLRAQDPSQGFLLVGLGMGAVAGGLI
                     LAGEYALRRLSFGIIVGGAVGLAGGLVLTGLVEWVGSAVFDVETFLFHIGGLVFLLGF
                     PYLGLAMGARFGQEQFPGVHPGQSSGSSQACLKVLDTSVIIDGRVADLCETGFLEGPF
                     LVPHFILNELQHIADSSDSLKRARGRRGLDILNKIQKMPEVDVRIIEEDFPHVKEVDA
                     KLVVLAKKVGGRIVTNDLNLNKVAELQGVRVLNINELCNALRPVVLPGETIRVFVLKE
                     GKEAGQGVAYLDDGTMIVVDNARRCIGRNVDVTVTSVLQTTAGRMIFTRLKEESEREE
                     YQVARG"
     gene            37727..38422
                     /gene="ispD"
                     /locus_tag="PK063_07955"
     CDS             37727..38422
                     /gene="ispD"
                     /locus_tag="PK063_07955"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: protein motif:HMM:NF013308.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HMZ97021.1"
                     /translation="MALVPAAGRGLRMGGSVPKQFLALGGRPILAQSLHVLQASPVIH
                     EIILAVPQADRQYCLDHFVAPGEFGKVTKVVSGGAQRQDSVRHALAEVSEADIILVHD
                     AVRPFLTGDMIRRVVDAAAEHGAAIIALPMRDTVKYVGAGGVIERTIDRGPLWLAQTP
                     QAFRRACLEEAHRKALLGNIHATDDAHLVELLGKPVVVVEGSGENIKVTRPEDLVIGE
                     AILQSRTATRSAE"
     gene            38419..38901
                     /gene="ispF"
                     /locus_tag="PK063_07960"
     CDS             38419..38901
                     /gene="ispF"
                     /locus_tag="PK063_07960"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008685 - 2-C-methyl-D-erythritol
                     2,4-cyclodiphosphate synthase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HMZ97022.1"
                     /translation="MTGVRVGCGWDIHPLVAGRKLILGGLEIPHHQGLQGHSDSDALV
                     HAICDALLGAMGEGDLGRHYPSSDQRFKNISSLKLLEDVVGKLRAKGYRLANVDSTII
                     AQAPRLSPHLAAMQKSIAGVLQIDPDLVNVKVKSGEGLDAVGREEAIAAQAVCLIERD
                     "
     gene            38898..39590
                     /gene="cysE"
                     /locus_tag="PK063_07965"
     CDS             38898..39590
                     /gene="cysE"
                     /locus_tag="PK063_07965"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HMZ97023.1"
                     /translation="MSCKADDARTAIPAMLKAIAQDLQAIFDRDPAATSRLEVILTYA
                     GFHALLAYRLAHWLKQHQVPFLPRAVSQLARWLTGIEIHPSAKIGASFFIDHGMGVVI
                     GETAEVGDHVTLFQGVTLGGTGKERGKRHPTLGNHVVVGAGAKILGGITIGDNVKIGA
                     NSVVVKSVPPNSTVIGVPARIIKSQGERLPDATMDHTNMPDPTADRFAALEMELIELR
                     KKLENQDTGKPR"
     gene            complement(39728..40045)
                     /locus_tag="PK063_07970"
     CDS             complement(39728..40045)
                     /locus_tag="PK063_07970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PsiF family protein"
                     /protein_id="HMZ97024.1"
                     /translation="MKHLCAVLSSIVLAAVLVTPQLSYAGAQQNKMKTCNADADAKGL
                     SGEGKGEQRKAFMKECLSAKPEKAAAGASQQNKMKTCNKDAKAKNLAGDERKKFMKEC
                     LSN"
     gene            complement(40127..40891)
                     /gene="truA"
                     /locus_tag="PK063_07975"
     CDS             complement(40127..40891)
                     /gene="truA"
                     /locus_tag="PK063_07975"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: protein motif:HMM:TIGR00071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HMZ97025.1"
                     /translation="MMTTFKLVLEYDGTRYSGWQRQLNASTVQAAVEAALAAISQTRL
                     TVVGAGRTDAGVHALGQVASFKTDRGLSPREWLRALNAHLPSDISALSVDAVPEHFHA
                     RYSATGKLYEYHILNRSERAALLRERAWSVYQPLNVAAMADAAAVLLGSHDFSSFETA
                     PTDNDNPHCRMQQSALRREGDLIVCSFYADRFLKQMVRSLVGTLVDVGRGKRSASDMD
                     TILKARSRPAAGRTAPPHGLYLVRVDYDAASAPPVT"
     gene            complement(40936..42255)
                     /locus_tag="PK063_07980"
     CDS             complement(40936..42255)
                     /locus_tag="PK063_07980"
                     /inference="COORDINATES: protein motif:HMM:NF013670.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HMZ97026.1"
                     /translation="MNWLFRLCLLLTLGWFLAGSASLSSAEMPSEPSWPQIPQPSGDA
                     AAPQFLLIKQDSAGTSRYPIIVRDLRTWSTPDGTRLVLDLNHKASFTETHVRNPDRVV
                     IDISNAILGKSSRQRVSGGTIPQSFHITQSRPRVVTITLARTQGSKYKAFALDNPDRL
                     VIDIYHKAKDQIRQIGETSSTSPSAPAVALPTPPTIPSPTVTEPVRPVAPKPASQIQT
                     IVIDPGHGGKDPGTIGQHGTTEKDVTLKVGMLLKDLLSTLPNTRVLMTREKDAFIELE
                     DRAKFANGKNADLFVSIHVNSHPHKGVRGLEIYHFGEAKDQRALEVAARENGTPLNST
                     GLGVEYILADLLTTKKIEHSQELAWTAKQAMVTNLNGRYSTIDHGVKTAPFYVLRFTT
                     MPSILAEIAFMSNPAEEEQMRTQPFLAHIAESIFEGVKTYLRTNPSR"
     gene            42358..42891
                     /locus_tag="PK063_07985"
     CDS             42358..42891
                     /locus_tag="PK063_07985"
                     /inference="COORDINATES: protein motif:HMM:NF017774.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HMZ97027.1"
                     /translation="MATHLLVDGYNLLGSARMAGPAGPGRLEAARDGLLHALAGYRQR
                     KGHAITVVFDGWQGGLGAEQREFQSGVEVVYSKRGERADQVIERLARLYGRDCAVVSS
                     DHEVINAARAAGAFVIGAPDFRAKLYQKPTRHQGPAFKELDRGEAEVVKRSKDKGGNP
                     RKLPKSQRKRNQQLREF"
     gene            complement(42878..43657)
                     /locus_tag="PK063_07990"
     CDS             complement(42878..43657)
                     /locus_tag="PK063_07990"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HMZ97028.1"
                     /translation="MLIDTHTHLDDARYASDRDAMIARAREAGVETMITIGCDLATSR
                     SAVALAGQYPFVYASIGVHPHEVKHITDSWYDELRQLAREHKVVAYGEIGLDYHYNHS
                     NPDEQRLRFREQIQLARELKLPVIIHTREAQDDTIRILKEERASEIGGVFHCFSGDAW
                     LAKDALELGFYLSFSGILTFQNATMLRDIAKTVPADRLLIETDCPYLTPIPHRGKRNE
                     PAYVKHVAETLATITSNGDTLTADDIGRLTSDNARRLFKIP"
BASE COUNT         8754 a        11149 c        13574 g        10377 t
ORIGIN      
        1 ccatcacctc gggttcagca tgccgtcctg gcagaacggg ttgcagcgat tcctgaaagc
       61 tctgccggcc ctgtcctcaa tgtcctcccg cacataggct gcgcccttct ctgaaccgtc
      121 tcatcagctt aggtggccgc cttcctggcc cggcacattt cttgtgcaac ctcgctcttt
      181 tctctatact gctagcgaga aggttccctc gtgctctggg tgtgttcctg ctgcaaacct
      241 gaattgttgc catcgttcgt agaaaatttt caatatcggc ttggtcaaca gtggtccagc
      301 gtcaagacca ttgctcacag ttatatggcg agcgatgcgg gtacgtctcc tcattcgtcc
      361 actcagcaat gtgggaattt ttcgccagat acccaagctg atcggaagta ttttagaggc
      421 aaagttccca taggcccagc tacacacgaa atcgttctgc cggggaatct accgaggaat
      481 ctaccgagtt gccgattcac aggatagcga tgtaggtgcc tgattccatg tacgacataa
      541 aaattaatcg gtagtcgagc ggctgcggtt gcaaagcccg cactgagggg tagtcgatgg
      601 aaaagcaggc acgtattttc gtggctggac accagggtat ggtcgggtca gcaatcctgc
      661 gggctctgac aagccgtggg tacgagcgac tgatcgtccg cgccagtggg gaattggatc
      721 tgcgcgacaa tgtgcgggtg gccgcatttt ttgaagaggt caagcctgac tatgtgttcc
      781 tcgcggcagc caaggtcggt ggaatcctcg ccaacagcac gttgcctgca gagttcattt
      841 acgacaacct ggcaattcaa accaacgtcg ttcatcaagc ctatgttcat ggcgtgaaga
      901 aactgcttct gctggggtca tcctgtatct acccccgtga ctcgcctcag ccaatgaagg
      961 aggactatct gctaactggt cctctggagc cgaccaacga agggtatgca gtggccaaaa
     1021 ttgcggggat caagatgtgc caggcctatc ggcagcaata cggctgcgac ttcattgtcg
     1081 ctgtgccgac gaatctgtac gggccgaacg ataactttga tttgcagcat tcccatgtgt
     1141 tggccgcatt gctccgccga tttaacgaag cgcgggaaca gggcggggaa cccacgttat
     1201 gggggagtgg cacgccattg cgcgagttta tgcatgcgga tgattgcgcg gacgcctgcc
     1261 tgtttctgat ggagcggtac tcccatgcag agatcgtgaa cgttggggcc ggcgaaggaa
     1321 tttcgatcgg ccggttggcc actttagtgg ccgaggtcgt cggctatcga ggcgatatcc
     1381 attgggatcc gaccaagccc gatggcatgc cacgaaagct catggattgc ggtcgcatga
     1441 aggcattggg atggacacca cggattccgc tcagagaggg cttgcaagat gcgcatcgtt
     1501 ggtatcaagg tcacgtaaag aggattgctg attaacagct gagtgcatac agggttgggg
     1561 cggggaaaat gtggactgcc gggttgtagt atagaaacgg attgagaact atgatggcag
     1621 aatgagagag taggccatac taatctcttc acctttcctg gtttggtgct cgcacgggct
     1681 gttccgttat tcaagcattc agctaggatt tgcaaaattc agggtcaagc cagatgtgtc
     1741 tatgggtgtt gattcgtgcg atagtcgccg acgttcgcga ctgtgagaac attatttcta
     1801 gaactgccgc taattggggg tatacatcgt gacaagcaag ccgctggtgg tcgttccaga
     1861 cgagaaaaca tatgggctaa agcctggcgc ggaagagttt cccttgatgg tgattatctc
     1921 catcatttac ccgtgcaaca tggggtgccc aaactgtccc tataccgaca ccaattcaga
     1981 attgcgccgg ttctaccacg aacatgacgg cgatttaatt ccggtgaaac tatgggagaa
     2041 aattgctgat gagtgtggcc cttatggcgc atggatgcgg tgtaccggtg gtggcgaacc
     2101 catgctccac ccgaaaatgg tcgagatgat tgaatatgcc aaggcgaaag gggccagggt
     2161 ttggttgaat accaacggca gtatgtttgg tccaaatgcc aagcatcggg agcggttgga
     2221 acgcgtgatc cgagccggaa tcgatctcat tgaattttcg atggatgcgg cggatgccga
     2281 aacctattcg gtcttacgtc caccgcgaag tgggaagact ggggatccgg agcaatggtg
     2341 gacgaagcat gtcggcaatg ttcgcgccgc gttggatttg aggaagcagc atgtggcgac
     2401 gacccgagtg gtcacctcca tcattcggca agaggcgatc gagggcagac tggatgatgc
     2461 tgttcagttt tggctcaagg atgtcggcgt ggatgaggtc attaccagaa agtttctttc
     2521 ttgggatgac aatacgacga tccagcttgg gaaaactctc gaccggcatt tatacgcgga
     2581 ccttccgaaa cagaaaaaag aaccgtgcgt atggccgttt gagcgattga atgtggatac
     2641 cttagggcgg attgctctct gtgggcagga tatttctttc aaaacctcag agctctttcc
     2701 caacgtgaag gacaccagca ttaaggaaat ttggcagggt gaaatgttca cgtggtatcg
     2761 caggatgcat ctcgagggcc gcggggcgga atgtttcccc tgccgtgggt gttcggcctg
     2821 gttcgctggt attcgtgatt gggatcatgg gtggcagaag gtcctccgga attcagggga
     2881 ccatttgaag gaagtgatgc gaagggactt aggcgtagaa gttgaggtct ttcaaccgaa
     2941 agtctagggt gaggcccggc acgttgagtg agtcaatgtc tgagaagaac gtcgttcaga
     3001 ataaggctga ggcgcaccgt gggcgcgtga ttgtcttcgg gtacggcgcg ttagctgccg
     3061 ccgctgttac ggcgttactc tcggctgggg cggaggtaat cgcggtggtg gcaccctcga
     3121 accgatccgg cgacgatgtc gactttatca aagactttgc ttgcacggcg ggaattccag
     3181 tactcgtgca gccaccaagg aagacgattg cgccattcgt ccaagactta aagcggcttg
     3241 atcctgatgt cattgtggtg tggtcatacc cgatgatcct cccccctgat gtgattgagg
     3301 tgccacgaga gggaacggtc aatgtgcatg gtggcctgtt gcctgagtat cgcggggggc
     3361 atgtcatgca gtgggccatc attaatggag aatcggagac aggtgtcgct ttgcactata
     3421 tggatgaagg aattgatacg gggccggtca ttgcacagag acgctttcca attgagcgag
     3481 atgacgatgc agccacggtg cgggagaagt tgaaggaggc cgggatggcc ttgctgaagg
     3541 aatggtggcc tgccatcagt caaggacgag cccccaggga aaagcaggat gaggcgaccg
     3601 ccaagtatca tcggcttcgc acgatcgacg atggcttgat caattggcat gcatcagcga
     3661 cggaggtctg caaccttgtg cgggctctgg ttcgcccgtg gcccggggcc tttactatct
     3721 tgaacaagaa aaaattagta atatggaaat gtcgcctcct tgtacaagag accagtgggg
     3781 tgccggggct tgtcgtgcaa gttgacgcgc agggagctcg ggtgtgcact cgagatcgtg
     3841 acgtgcttat tgagacggct gagctggatg gggaacgcat gaccggtttg gacctgaaac
     3901 gaatcatgca ggcggggact tgtttgggcg cgtgagtgat gaaggagtcg cgatcgcgat
     3961 gagtatgaag gagcgggtgt atgtcatcta tgacggacaa tgccgctttt gtattcgtag
     4021 cctcaagctg ttcagcgcag ccgatatttt caaggtcttt cggttttatg atgcccatga
     4081 cgaacagtcg gtcgctgcgt tgtttcctga gttacaaggg gccgactttg acaatgccat
     4141 gtttgtcgtg accgagcgac gcgaagtgta taggggattt tttgcgtttc gccggatgat
     4201 atggagtagt ccgttattgt ggccgttgat cccggttttc tattttcctg gcgctacccc
     4261 ggtgggaact cgcctctatg cgtgggtggc gaaaaatcga ctgaagtttg ggtgtcagtc
     4321 cgatgcttgt acgctgccag ctcgccttcc caaagatcct tcctcggatc acgttgatgt
     4381 ggtgcctcat tagtctgcgt ggtgcgcata acatcgtgag ttcagttggg ctataccttc
     4441 cggtaggaaa cggttgaccg ctatatggag atgtttttcg cgccacaggg ttttttgcac
     4501 ccggagctga gcctctccgt gcagatgttc atgcgtgtcg tgtatgggat gttgctgtgc
     4561 ggcatgttgt tgttggcgat ccctaactgg cggcgctttt tcttgagcga gcgctgggga
     4621 gggtatgctc agtcactacg agaggttgag ttcatacaga acccgcttgt gtttccgctc
     4681 gtaatggcgg tgtggtttgc ctgcggcgtt tgtatcaccg gtggctggtg gacgccatgg
     4741 ccagctctac tcaatctcgt gctctgcagg tatttctttg tagggatgcg ctggaagggg
     4801 ttactgcggg gaatgggtgc tcccggctac attctctact gggggggatt ggcgatcaca
     4861 gttctggaat ataccctcca ttatgcgcca gagctgcggt ctctcgcatt acaagttttg
     4921 caggcggatt ttgcgtgtgt gtacatctcc tccggagtct acaaactctc tgccggttat
     4981 gcgaagaacc atggaatgga actcggcatg accaatcctg cctggggata ctggtggaag
     5041 cactaccagc acttctcccc ctcccatccc ctcttccggt tcctcaatca ccttgcctgg
     5101 tcttcacaaa ttatcgcagg cattctcatg ctcttacccc caactcgatt catcgggggc
     5161 atgatcatat tcgggatgtt tgcgttcatc gccactcaga tcaggctggg gctcttgtgt
     5221 gaaattgtca tgttctgcag cagtctcatt tttcttcatc ctggcagtct cggggatatc
     5281 gttgttacgg ctgtggtcgg acaggtccag tctccctctg tcgcaagctt tgcgttctcg
     5341 tctgtggcca atacggtcct gggttgggca ctagccatct acctcatcct gctgccgttt
     5401 gcacacgtgg gcctctcgta taacttttac ctgcggcgct cactgccaaa accgctccag
     5461 atggccctgg agcgctatac gaatttcttt ggattgatcg tttggagagt attctctgtc
     5521 gatatcgtca attttttcat tcggatttat cactatccga aagcgcatga atcggatcga
     5581 caacttattt ccgacgaaag tgtaggggca cgactacggt ttggccacgt tgcagagtcg
     5641 attgtgctcg cctgtatctt tacgacactg aagtattatc ctcacaatag cggattgttc
     5701 cacgaacgtc tgcttcgata tgcacgaaca tttccctgcg agaagggtga gttgttgatt
     5761 tttgagtatc tcagtctacg aaaagaaccg gaccgatttg tgtttgcgcc ggttgcggaa
     5821 tatacggtgg ataccgcggc catgacagtc gtggaacgcg tgatcgatcc ttcggtatct
     5881 gtgcgggcgc cgcatgcggt ctcaccggtt catgaagggg tgcggccagg gacctatgct
     5941 ccggcagggg ggcgttaaag gatatgtgtg gaattgcggg acggtttggt ccaggcccaa
     6001 atcaggctgt caaaaagatg gtcgcgctcc tcgcccatcg tggcccagat gatgaacatg
     6061 tggtgtcggg gagaaacttc gccatcggag ccagacggct tagcattctt gatcttcagg
     6121 gagggcggca gccaatctca aatgagcggg agacaatctg ggcggcccaa aatggagaga
     6181 tttacaactt tcctgcactt cgaaatgagt tgctcgagcg tgcacatgtg ctcaagaccc
     6241 actgcgatac tgaagtcttg cctcatctgt acgaggagca cggggcggca ttcccaaaga
     6301 aaatagacgg tatgtttgcc gttgccttgt gggacggtga cggccaagtc ggctatctgg
     6361 cccgcgatcg aacaggaaag aagcccctct actattgtct gcacgatcag gcgctctact
     6421 tcgcgtcgga gatcaagtcc ttattgcaaa tcccgggctt cactcggcgc ttgaatcttg
     6481 atgcgctgca ccaatttctc agtttgaagc acgtgcccca tcctctttcg atattcgagg
     6541 gcattgccat gcttccccct gcgcatatgc tgacgtatcg cgcgggacag gaaccagttg
     6601 tcagccgcta ctgggatctg agcttcgcgg gaagcgacac gagcgcggga atgacggagg
     6661 aggagattac tgaccggctt cttgtcctgc ttcggcaggg ggttgagcgg cgtctgttgt
     6721 cggatgtacc gatcgggttc tttctgagtg gtggcattga ttccagtctg tcgacggtgc
     6781 ttgctgcgga actctcgcct tccaagatca aaagtttcac gctgacgtat tcgcgggaat
     6841 cgacgaccga agggaaagaa gaggatcgcc gttgggctcg ttgggtcgcg gaacaatatg
     6901 gaacagaaca tcacgaggaa acgatccaag tgtccagttt tcccgaaaac ctccgccgca
     6961 ttctgacatg ttttgatgag ccctatgcgg gagtggtttc gacgtacttt cttgctcaac
     7021 tcatgagcca acacgtcaag gtggcactct cgggtgacgg ggccgatgaa ctcttcggaa
     7081 gctatctctc tcatcgtcta gccgttccgt tggcaaattt tcagacctac ctgcagactg
     7141 ggaattcggc acttattcgg cctttcgaac agcaggtgga ttttcttgcg cggatggccg
     7201 atccccagga ctggggatgg cgatacaaat tgctggtatt tagtgatgag gaaaaggacg
     7261 cgctctacag cgaagaaatt gcctcacaca tgcgatcgta cagcacccgt gatcgactcc
     7321 ggcatgattt ctctgaacta tccgcgcgtg atcctctgaa tcggatcctt gagtcggaat
     7381 ttcgtactat cttccctgat caagttcttg cctttgtgga tcgcctttcg atggctcatt
     7441 cacttgaggt tcgcacggcc tttctcgata ccgacttcgt cgagtttgtg gctggactgc
     7501 cgggatcgct gaagatcaaa gacggagaaa ccaagtactt gctcaagaag ctgggactac
     7561 gatactttcc gcgcgagatg gtgtatcgca agaaggaagg ctttttgatg ccgattacgc
     7621 aatggctgct acgggatcta gagtcatatg ttcgagagac cctcagccca gagcgactgg
     7681 ccaaacacgg gttgtttcgt gcggcctacg ttcagcggct ggtggatgcg ttataccagg
     7741 cgcagccgga tcatctcgcc gtcaacaaag tgtatgcatt ggttgtgttt caggagtggt
     7801 atgacttgta tatggtttaa ggtccatggt tcgaatctaa cgctaagagt gcgagtattc
     7861 ctgcctgaat aatgcacgat ccgaatcttc agtcatccat cacgctgtgt gtacttcagc
     7921 ctggctattt gccgtggctt ggcttctttg atcagatgcg tcgaagtgat atcttcgtcc
     7981 tgtatgacga tgttcagtac gacaagcacg gatggcgaaa tcggaatcgt atcaagactc
     8041 cgaaggggcc tcattggttg accgtccccg tccgccataa gggattaggg tggccacgta
     8101 tcaacgaagt tgaaattgat aaccagacag tctgggggaa aaagcatatc ggaacgatcc
     8161 gacagtttta tgcaaaggcg ccttatttgg ctcaatacct gccgatgctg gaagaccgac
     8221 tgttacggcc ctggacgtta ctggttgacc ttgatttatc tctgatcgac ttaatgtgtg
     8281 agtggttgca acttaagcgc gacgtcatcc gtgcatcctc gctcggcatt gaaggagatc
     8341 ggagtgacag attgctcgca ctgtgtagac attttggcgc aacacggtat ctcagcggtg
     8401 acgcggcgaa gacctatctg gaccgtgagc tcttcgcgca aaatggaatt gaggttgagt
     8461 ggcagggttt tcagcacccc gtgtatccac aacagcacgg ggagtttgtc ccgtttctct
     8521 ctgctctcga tctcgtgttg aattgtggac cggatagcgc ggccatctta cgcggccaat
     8581 gaaaaaggag gattggtgaa aaccatactg attaccggag gggcgggttt cattggcagt
     8641 aattttgtgc gctatctcta cgacaagtat ccgaactatc gtttgatcgt gttggatgcc
     8701 ttgacctacg cggggaatgt gaagaatctg ccggtggaca ttaacaatgg ttccgacgag
     8761 cgactgatgt tctggtatgg aaatgtgcgg aacgccgagc tggttgatac ggtggtatcc
     8821 caatcggatg tggtgatgca ttttgctgcc gagtcacatg tcacgcggtc aatttatgac
     8881 aacttgctct tttttgagac cgacgtgttg ggcacgcaag ctgttgcaaa cgccgtactc
     8941 aaatatcgtg ataaagtaga gcggttcatt catatctcga catctgaggt ctacgggacc
     9001 gcggaatcag aaaaaatgtc ggaggagcac ccattgcttc cgatgagccc gtatgcatcg
     9061 gcgaagtgcg gcgctgatcg attggtctat tcgtattggc agacctatgg aatccctgcg
     9121 atcattgtcc gcccgttcaa taattatgga ccgtatcaac accttgagaa ggtggtgccg
     9181 cgcttcatca cgagctgtat tctcgatgag ccaattaccg ttcacggaga cgggtctgcg
     9241 gcgagagact ttatctatgt acaagatcat tgcgaagcgc ttgatttgat tctgcacgcg
     9301 gagccaaagc gcgtatttgg tgaggtgctc aatttaggga cagggcggca tatcagtctg
     9361 atggagatcg ctgataccgt tcgggcgctg atgaagccga agaagagccc cattcaattt
     9421 atcggtgatc gtcccggaca ggtgttccgc cacacgtgtg atcattcgaa ggtctcgcgg
     9481 attctcggct ggcagccgcg cacctcattc gagcagggcc tcgagcgaac gattcaatgg
     9541 tatcgggaga acgaagcctg gtggagaccg cagatgtgga tgagacggat tcccatcgtc
     9601 accgcggcgg gtaagcggga gctacactga gatgggcatt cctttctatc gccatgattt
     9661 aggcgaaccg gaagttgagg ccgtgcgaaa ggttctcgcg gggccaattt tgacaacagg
     9721 ggaagtcgtc gagtcgtttg agcgacgctt tgcggcctat cttggtgtac cgcatgcgct
     9781 ggccgtgacg agttgtaccg gtgcgcttca tctttccctc ctggcattag gcatcggcct
     9841 tggagacgaa gtgatcacga cgccgatgac ctttattgcg tcctccacgg ccattctcga
     9901 agccggggca aagccagttt ttgttgatgt ggaatcgcag acgggcaatt tagatgcgac
     9961 caaagtcgag gcggcgatta cgccacggac aaaagctatt ctgcctgttc acctgtacgg
    10021 acagatgtgc gatatggtga ccattcgcaa aatcgctgat caacatggcc tgtttgtgat
    10081 tgaagatgcc gctcattgcc ttgaaggtgt tcgtgatggg gtgaagccag gtgagttggg
    10141 agatacggcg tgcttctcct tttatgcgac caagaatctg acctgcggag agggaggggc
    10201 tcttgtgacc aaggatcggg ggctagccga aaagcttcgc ctgctcaggc tccatggcat
    10261 gacaaaaacc gcagcagatc gtcaccgcga gggttatcag cactgggaca tgaccgtgct
    10321 gggttggaag tacaacatgg ataatatcca cgccgcgctc ctccttcctc aaatggatcg
    10381 tatcgaacag aattggtcca agcgtgatac cgtggcccgg tggtatgaag gcttgctgtc
    10441 ggattgccct ggtgtgtcgg tgccaaaatc tcatccgcag gtgcgtcacg ccaggcacct
    10501 ctttcccgtg tttgttgagg gcgggggacg agacgcaatc atccaagggt tgcaggagga
    10561 tggaattggc agtgtggtga attatcgcgc aatccatctt ctgagctact ttcgggacac
    10621 attcgggttt cgtgtcggcg atttcccgca tgccgaaaaa attggcgata gcgtggtgtc
    10681 cctcccgttt tatccggcga tgaccgaaaa ccaggtcacc caggtcacgg caacagtgac
    10741 gcgcctctta aaggcgcgga ggtgagcctt caatggtcct gcatagcctc agtttctgtg
    10801 catacctgag tgtgtaatcc gactgtccgc acccaggaac ccgagtccag gcgccacagc
    10861 agctcttcgg gatcacccgc gtgtctaccc taaaactttc actggtcggg cttggggcaa
    10921 gagtgattct cctggtcatc aatgtgatca gtgtggttct gcttgcccga tatttggagc
    10981 ctcaagggcg cggtgaatat tttctctttc aaacgctcgt gtcagtgctc agcgtggtgg
    11041 gtgattgtgg actctcacaa agcgccaatg tgtttgtcgg gcggagtgcc catcgcaaaa
    11101 agctcatcca tgcatttgtc agtaaggcgg caatcatctt gtggattggg atgagtggaa
    11161 tcggtgggtt ggtgctgtgg atggccggtg agcagctcct gcatgatttt ccagcgcgct
    11221 ggcaatgggc ggcgtttgca atcctgccat gcatgctgta tgcggggttc tggaatagcc
    11281 tcatgatcgg attaggagaa attccgcttc tcaatggcgt gcaactcgtg ataggtcccg
    11341 tacagctcat tctcattctc gtgcttgtcg tggggttttc cggaggagtg gcctcggccg
    11401 tgacaatcta tctctctacc atggtgctgc aatgcgtgct catggtggcg ctatcgcgtc
    11461 gtttgggatt tcttggcgga agcgagtatg ttgaggcggg cttatcgcga cagatgctgg
    11521 cattcggtct tcgtgcctat cccaatgcca ttgcgaccat ggggtggatg cgtattcccg
    11581 tgtttgtgct caatgcattt cacggagccg cttcagtggg gattttttcc gtggcgcagc
    11641 aattggcgga gagagcgttg atgcccatcc aggccgcgca agacgccatc tatgggaaaa
    11701 tgtcggcgtt atcgccacgc gaagcgattg cggcaatgaa tcgctacata cgaattgtgg
    11761 tgtctgggat ggtcgccagc acggtgggag ctatgcttct tgcaccgtgg attgtgatgg
    11821 cgctgtttgg accatcctac cagccggccg tgtatgtgtt ctggatcctt ctcgtcggag
    11881 tggtatttgt gagtgtgtcc atgatcgtca gcacctatgt tctgggccag cgagggcgtc
    11941 caggtctcct ctctctgcta gctggagcga acgcgtgcat ttgtctggcg tcgagttact
    12001 ggctaattcc aacatgggcg gagatgggag ccgccatggc tttggcgttg acccaagccg
    12061 taggggctgt tgtggtgttc ggtctctatt ggataacttc ctctgcaacc ctacgcgaaa
    12121 cactcttgct cacatccgag gatgtcacga gtgtgttgaa acaactgggt aaattgacat
    12181 ggcggaaggg cacgcagagc taacatcagc cgatcccatc agcgtggtgc accttatcga
    12241 cggactgggc ggcggcggtt ccgagcggtg ggtgtgggat attgtccgtc tttctgagcc
    12301 gactctgtgc aagcatttcg tgattagctt ctttcccgat aacgcaaagt tcgtctattc
    12361 tgagccgtta cgcagtcgag gcgcctacaa gcaacccgcg caccatcctt tcttggaatg
    12421 gcttgaacga ggcatccaga ctgttgcctc ccagtggtac ctcttgccta tccgtaagac
    12481 actttccgga ctttggtggt tttgcaatgc agtggatgtg tggtggcggg tcgctgttgc
    12541 gctcgttcag aaaagaccgg atgtcattca cgtgcatacg tttcatggcc ttagggtggg
    12601 attagtctta cggcgaatgt tgcagatacc ccttgtacat tctgtcccag ccttgttttc
    12661 gcaaatgacg gatgcaggat tccacggaat acctcagctc tatcggtcga atcagcaatg
    12721 ggttgcccga ttcatcaccg gggcctccgt agcggaattg cattcgatcg gaatcccgga
    12781 cagtaaaatc atgcctatcc atggcaccgt tgatctaacc tcaagcacct cgatgagaaa
    12841 gcagaagcag cactactaca ctgccctgcg agatgagttg aagttaccgg gggacgcggt
    12901 tatcgcgtta tcagttggtc gactgcaccc gtcgaaaggg catgcgtttg cgctcgaggc
    12961 ggtgccggag cttgtggctc agtttcccca gctgcattgg gtagtcctgg gtgaaggaga
    13021 acaacgagag gcattggagg ctcgtgcgag cgaactcaag gtaagggaac atgtacattt
    13081 gcttgggttt cagcgggacc cattgccgta ttatgcggcc gccgatattt atctgaggac
    13141 gccggtgttt gaaagtgaaa atttgtccag ctaccaagcc atggcaatgg gccttccagt
    13201 tgttggattt gataccggat gtgaaacaga gctactgggg aagagtggcc atggcgtgtt
    13261 ggttcccgcg aggaattcgg aagcccttgc aaaagccgtg gtggagatgt tgagccttcc
    13321 tgaccgaggc gcgcgaatcg gattgcgcgg cgttgaatat tgtcgtcagc atctggacat
    13381 cgatcgaaca atttcggatt tggtgcgcct ctaccagcat ctgggagcaa agagggcgtg
    13441 attgttggtc tgcgcgtgag tcagcaggcg accggctgcc atgttcgggg ttgagggcat
    13501 gaaagtcacg tttgtcatat cagctctttt tgcgggcggg gcggaacgtg taatctccat
    13561 catggccaat tattgggctc gcaaagggtg gggcgtcacc attttgtctt tcgatgatgg
    13621 cgagaccccg ccatttttcg aggtcgatcc ctcagtgcgc cggatgtctt tgggcctttt
    13681 gggagattcg gccggactga tcgcggggat tcggaataac atcaatcgag tggtgaggct
    13741 acgtcaggcg attctacgaa gccagccgga cgccgtgatc agttttgtcg acaaaaccaa
    13801 tgtgctgact ctctttgcga ctctggggtt gaagcttgaa gtcatggttt cggagcgtac
    13861 gaacccctat caatactcaa ttggtcggat ctggggcgcg ctacgatggt gggtgtactc
    13921 tcgagctgat cgaattatcg tgcagaccca tgctgcccgg gcctatttct tgccaaaatt
    13981 tcagcgtaca gtcagcgtca ttcccaatcc cgtcctgccg tcctcgagca actatgcgat
    14041 ggtgaaccat cgccctgcgg gatgcatgat tctcgccatg ggtcggttgt ccaaagagaa
    14101 ggggtttgat gaccttttgt atgcatttcg caaggtgaac gatcagcacc ccggctgcac
    14161 gctcactatc ataggggagg gccctgagcg cggagaactg gaattgttgt gcgagaggct
    14221 cggcctgtcc ggatgcgtgc tcctaccggg actcgtgacc accatagaag tgtttctgcg
    14281 gcaagcaagt atgtttgtgt tgagctcccg cttcgaaggg tttcccaatg cactgtgtga
    14341 ggcaatggcc tatggacttc cagtgattgc cacggattgt cggagcgggc cccgcgagat
    14401 cattcgtgat ggtgaggatg gccttctcgt cccgcctggt gacagggacg ccttggcgac
    14461 tgcgatggat agtctgatgt cagatccaga gcggagagca cgattaggcg gtcgggcgat
    14521 ggacatcacg cagcggtttg gggtggagaa agttatgggg atgtgggaga agatcctcga
    14581 accgatcgca tagtgaaacg gggagcatga tgacgcaaca ggcacaggaa gtcgcggatg
    14641 gccgtcgctt tgaatttggg cagaactggc gcaggtttct agaggatctc actgaagagc
    14701 ggattggtcg tgcccaggaa tcgctccaag caatgctcgg gttgaagagc cttgcgggac
    14761 agcgcttttt ggatatcggg tcgggtagcg gtctgttcag tctggccgcc aaaaggctgg
    14821 gggcctccgt tcgttctttt gactatgatc cgcattctgc tgcctgcacc gctgaactga
    14881 agcggcgcta tttccgggat gatgacacct ggatcgttga agaggggtct atcctggaca
    14941 tggcctacgt gcagtcgctg ggaacctacg atatcgtcta ctcctggggt gtgctccatc
    15001 acaccggagc catgtggcag gcactggaca atgcctcccg tttagtcgct gaccagggaa
    15061 cactctttat cgccatttat aacgatcagg gcggggccag ccgccggtgg ttaatggtga
    15121 agcgtgtgta taatcggtcc cctcaatggg ggaaaattct ggtggcatgg ctggcatgta
    15181 ttcgtcagtg gacgctcacc gtcgtccgtg acacgttctt gggcaaccca cttcggacgt
    15241 ggtttagtta caaggaacaa cggggaatgt ctccttggcg ggatgtgatt gattgggttg
    15301 gaggctatcc attcgaggtg gccaaaccag aggagatttt cgatttctat cggaaaaagg
    15361 ggtttgattt gcagcgaatg aaaacctgcg cgggtggtat cggctgcaat gaattcgtgt
    15421 ttcaccgcgt gtccacagag cgcctgtgaa agttcgtttc cttatccggt cgctgcagcg
    15481 gggtggagcg gagcggcagt gcgtggcgct tgcaaaaggg ttgcgccagc ttggccacga
    15541 tgtcggtgtc cttgtcttct attcaggcgg ggacttgtac gacgaattat tggcggctgg
    15601 aattcccgtt gaaagtgtcg ggaaactgcg acgctgggag ttggttggat ttttacagag
    15661 aatccggcgg tgcttacggc gagagcgtcc ggacgtggtg tacagcctgc tgcaggtgtc
    15721 caatgtggtg gcagcggtgg agaaactctt cgttcccacg ctgcgagtca catgggggat
    15781 tcgaaccgcc tccatggacc tgacgcacta tgatcgcctc gtccgcgtct cctattggct
    15841 tgaagcgcgg ttgtcccgat tcgcggatca catcatcgta aattccgaag ctggccttcg
    15901 ttatgcgaag gtggaggggt accgcacgga tcgaatctcg gttattccca acggcatcga
    15961 caccgaactg tttgcgcctg accgatccaa gggtaagacc gttcgatgct cttgggggat
    16021 cagggatgag gaggtgctga tcgggttggt cgggcgactc gatcctatta aagatcaccc
    16081 cacctttctg cgagcggctg cactggttgt tcggcagtgc gctctggtga aattcgtgtg
    16141 cattggaggg ggagattcgg catacaagga gtcgatggtc gcgctgtgcg cagagctggc
    16201 tttgtcagcc cgcgtgattt gggcaggcga acatagtgat atgcccgcag tctataacgc
    16261 actggacgtt gcctgcctga catcgaccgc cgaggggtgc cccaacactc ttcttgaagc
    16321 catggcctgc ggtgtgccct gtgttgcaac agatgtcggt gattcgaagc gaatcctggg
    16381 ggagattgga ggcatcgttc catctcgcaa ctcagaggcc ctggcgggtg ccatacaaga
    16441 attgttacga atggatggcg ccgaacgggc aaagcaaggg cagatgggcc gggatcgcgt
    16501 catccagcat ttcagtcttg atcggttgat cggtgatacg gcctccgttc ttgaggcgac
    16561 tgcgcgatga ccgttgtcgg gatgtgcatg acatgtgcag gccgctcttg tttcacggtc
    16621 gtcttccgat tcccggacgg cataccatgg tgcgacggtg accccttggg gacggtatca
    16681 gaatcggtga tgaaacagtc caagagtccc tgtgagttcg gattctctct gtcagcatga
    16741 ttcgaatcat ccatgtaatc tccggtcttg ataccggtgg cgccgaggtg atgctcgtca
    16801 aggtgttgca aggactagat cgcacacggt tcacgaatat tgtcatttcg cttacagacc
    16861 ggggacagtt gggagaacag atcgaagcgt cgggcattgc gctccacacg ctggggatga
    16921 agcgcgggtg tcccaatctt tccgcgctcg tgcggttacg gcgattgttc acgacactgc
    16981 agcccgcgat tgtgcaaagt tggctctatc atgccgatct actgagtacg ctggctgtca
    17041 aggtgtcggg ctcgcccatt ctaatctgga acctacgctg ctcgcacatg gatctcacag
    17101 ggtactcgcg tctcacgcga atcgtgcaat ggatgctggt ctggctctcc cacgtgccag
    17161 ttgcggtcat cgccaacagc gtagcgggga ggcagcagca tgcccgtttg ggctatcgcc
    17221 cacggcgctg ggtggtgatt ccgaatggat tcgatctgca gcggtttcgt cctgatcgaa
    17281 gtgctcgagc ggcgattcga accgagtggg gcctgtcaga cgataccgtt ctcgttgcgt
    17341 ttattgcgcg ggtcgatccg atgaaagacc acgccacgtt tcttgatgcg gccaagcgag
    17401 tggtagatgc gaaaaagaaa gcccatttcg tcctggtagg aaaggataca gagacgctcg
    17461 cgcccagtgt cgctaaaagg ggcttgacgg atcatgtact gctcttaggg catcacggcc
    17521 atatcgaacg gctgttacct ggtgtcgacg tggggtgtct cagttcgctg ggcgaggggt
    17581 ttccaaacgt cctcggcgaa gcgatggcct gtggcatacc ttgtatctcc acggatgttg
    17641 gcgatgctcg tgacattatt ggtgacaccg gactggtggt gccgctccgc gatcctgctg
    17701 cccttgccgg tgcgatgact gacctgattg atcgtgggcc ggcggggcgc gcgaaactcg
    17761 gatatgcggc gcgtgcacgc attgaggcgg aatacgcact gcccaaggtc gcggagtgtt
    17821 atgaagtcct ctataccgag ctcgcggcgc agtcccgatc accccgtgaa cggatgtgct
    17881 gacaaatatt ggacgttatg agaaacgggt tgcgtaccct atgtgtggca tagccgggct
    17941 tctcagccaa tctcgaggtg agttggatgc gaccgtcgcg cgaatggtgg cagcgatccg
    18001 gtatcgaggc ccagacgatt cgggcatctg gagcgatccc gctgcaggtg ttggacttgg
    18061 tcatgcccgc ctctcgattc tggatttgtc tccggagggg caccagccca tgtcgtcgcg
    18121 cagcggccgc tatgtgttgt cctacaacgg cgaagtgtac aatttcggtg agcttcgaac
    18181 ggagtttgaa gcagctggaa ccacgtttcg tggccattcc gatacggagg tcatgttagc
    18241 tgcgtttgac gcgtggggca tcgagatgtc cgtcaagcga tttgtcggca tgttcgcctt
    18301 tgcggtgtgg gacaaccaca cgcaaaccct gaccttgggg cgggaccgct tgggggaaaa
    18361 gccactctac tatggctggc aggggcaaac gtttctgttt ggctcagagc tgaagtcgct
    18421 caaggcgcat ccggcctttc gggccgagat agaccgggac gctttggcgt tattgctgcg
    18481 gcacaattac attcccgcgc cctattccat ttatcagggc atttccaagt tggtgcccgg
    18541 gtgtcttctc acggtgtctt tgtcacagcg aacgccgcag acgaaggctt tctggagtag
    18601 ccggcagtgc gtggaggcag gtctcgcaca tccctttgag ggaagtgaag cagaggcgat
    18661 gtctcggctt gaagccctgt taaaggaagc cattggccgg cagatggttg ctgacgtgcc
    18721 attaggcgca tttctttccg gcggaataga ttcctcaact gtcgtggcct tgatgcaggc
    18781 gcagtcaagc cgcccggtga aaacgttcac catcggtttc catgaagagg ggtacgacga
    18841 agcgacacac gcgaagctcg tggcgcgcca tctcgggacg gagcacacag aattgtacgt
    18901 cttgccgaaa gaggcgatgg atgtcattcc ccggctgccg accctctacg atgaaccatt
    18961 ttctgattcg tcacagattc cgacgtgttt agtcagcgaa ctggctcgtc ggcatgtcac
    19021 cgtgagcctc tccggcgatg gtgcggatga attatttggt ggatacaatc gttatttttg
    19081 ggccacaacc atctggcgcc gcatcgggtg ggccccccaa tcgatacgca cggcgttggc
    19141 aggtgcgctc acggctctgc cgccttccgc atggaatagt gtattccagc ggttcgcccg
    19201 ctttctgccg gagggatggc gctatgccaa tcccggggac aagttacaca aacttgccga
    19261 gacactggcg gtggcgacgc cagaggaaat ttactttgac ctgctgtcac actggaagca
    19321 tcctgccgaa gtggttcgcg gcgcacatga gccgcccacg gtattgaccg atcagacgca
    19381 atgggcgaac ctgccggatt tcgagcggcg catgatgtac cttgaccaga tgacgtacct
    19441 gcccggggac attcttacga aagtggatcg cgcggcgatg ggtgtgtcat tggagacgcg
    19501 tgtgccgttt ctggatcatc gcgtagtgga gtttgcctgg tcgctgccgt tatccatgaa
    19561 aattcgggat ggccaaggca aatggttgct gcgccagatg ctctatcggc atgtgccgaa
    19621 ggcactgatc gaccgcccca agatggggtt tggtgtaccc atcgatgtgt ggctgcgtgg
    19681 accgttgaaa ggttgggccg aggagttatt ggatgagtcg cgcctacaac gcgagggcta
    19741 ttttgaccct caagcgattc gcacgaaatg gctggaacac ctgactggcc ggcggaattg
    19801 ggcctattac ctttgggatg tgctctcgtt ccaggcatgg ttggagagta tgggcgactc
    19861 ggcacacaac ggagctcata ttcttgctca gtaatttctc ctttcgtcgc ctgcccgcgg
    19921 tttttgtctc gatatttctg atcgcatttg tgctctggtc agctggcgtt gaggacgtct
    19981 tgcggaggct ggccggattt cctccctggg ctgtggcaag catgctggca ttgctgacag
    20041 cgaatctgtt tgtggtatcg ttccggtttt ggcgggtatt ggcgcatttt ggcattgcgc
    20101 taccctggga catcgctttg cgcgccagca ttgccggtac cgtcgccggg ctcttcgtga
    20161 ttccgctgtt cggacagatc atgggacgcc aaggagtgct gaacagtttt ggcgtacaac
    20221 ctgtggtgaa tgccagtctg gctgcctatg aacgtgccct gctggcgctt ctcagcggag
    20281 tgctcgggac tctgggcgcg gtctatttgc tcggaagatc tgcggttagt gattttttta
    20341 accagatcgc acttcccgag attgtggttg ccgcaatcgg gggttgggca ttgagtctct
    20401 ggcttggagg ttcgaggttt gagaggaaat tgtccagacg gacgctgtcg tggacgaatc
    20461 ttgaacatgt aatgtcaatc gcaggtctga cccttacagg ccagctcctg atgctggcct
    20521 gtttcgtagt agggattctg gccgtcagcc aggatattcc catcgcatcc ttgttcgccg
    20581 cgtcggccct tattagcttg gctgccagca tgccgattac tgtcggaggt tggggcgtgc
    20641 gcgaggttgc ggcggtgtac gtgttcggcc ttctgggtat ccccgcggca gatgccctgg
    20701 cgatgtcggt catggtgggg ttgtgttcta cgctggtcat tctcgcgtcc tcaccgttct
    20761 gtttcagaaa ctctctcatg tctgatttgc ctaaaccacc agcggtgatg attcattcgg
    20821 tgtcggagat tgaagagttt actgcttggg ttttgggtac ggtggtggcg gtcgcggtgt
    20881 tttttcaggt tcacgtatcc ctgtctggtg ggcctatcaa cctgaacctg gcagatccct
    20941 tcgccattct ggctctggcg gcggtgagcc tgcatgcgtt gttcgcccgg cagtttccgg
    21001 tatggagagt tccccaattc aacttcgcgt tgtgcgtgat cagtttactg ttgctggtgg
    21061 ggttcgtaca cggttggttg gaaataggca tcacgcagtg ggcgctggga gggcggctcc
    21121 tggggtggtt ggtgctgctt ggctatcttt cgtcggggta tgtgatcgtg gcgaacgtcg
    21181 ggactcacgg actgcggcgc ttcgccgaaa ctctaattgc tactgctgtc gtggtcgtga
    21241 tgttgcaagt cgccctgcgt cttttgtccc actggggggt aaatgccgcc gcgcaactta
    21301 cacaaaactt cgaggggtat gcggggaacc gcaatgcttt tgcgctccag gtgctggcgg
    21361 gcatggcgct ctttttgggc tattctcatt tgtatgcaag acacaacatt cgtgtgccac
    21421 gctcagtacg accatggata ttttctttgc tgcttggcat cttattggct ggtctggtct
    21481 ggaccggttc gcgaacggct atgctggtgg gagcgatggc actggttctt gcttggctcg
    21541 gcggcatggc cgaccacaaa atgctcggct ggggatgata ttcgcggcac tgctctggtc
    21601 catagtccta ttggtgccac aaaaatatgg aaacatgtct gtccagagta aactatctta
    21661 cgagagcagt aatctggagc gttgggaaac attgacccac ggcttggaaa tgtggcagca
    21721 atcgccagtt ctgggtgtcg gattaggagt gtttaacgag aagagtccga tgtgggcggg
    21781 acacccacag gtcatccata gcacaccgtt gtggattctg gccgagttcg gcctgctggg
    21841 aggcgctgtg ttcggctgga catttttcct gctggcccat cacgcgatcc ggtcgggaac
    21901 tacccagccc gcaaattgca ttttgttgct actgctggtg gccttcgccg tatttagcct
    21961 cgctcacgaa atattttatc agcgcatcct ttggctcgtg ttaggagccg tgctgacgcg
    22021 gccgtatgcc caccgtaggc atgcatgagt aggtgtccca aattactctt tgtcgttacc
    22081 gaggactggt atttcgtctc ccaccggctg ccgctcgccc tggcagctca gaaggcgggc
    22141 ttcgacgtgg tggtggctac ccgcgaaggg gagcacggag aacgcattcg ggctgagggg
    22201 attcgcctta ttccctgtca cctctcccgt cgccgcggca atccgctgca agaaattgcc
    22261 atgctcgcgc gcctgtatcg gcgggagcgg ccggacatcg tgcatcacgt cgcactgaag
    22321 ccggtgctct atggggcgct tgcagctaag atcgctgccg tgcctcatgt ggtcaatgcc
    22381 gttgcgggac tgggctggtt attcacgtca aatacacttg ccgtcaaggc tttgcgcccc
    22441 gccttttgca ggctgctggt atggttgctt ggggcgtcgt ccagctgcac gatcgtacag
    22501 aacccggacg attttggttt gttgacccaa aagggagtgc cggaagatcg tctgcgcctg
    22561 atccgcggtg caggggtgga tacggaggtg tttgctcccc cttcccaatt gccgtctgag
    22621 cccgtcacgg tcgtattcgc ggcgcgaatg ttgttggata agggggtgcg tgaattcgtt
    22681 gaggccgcgc atgtgttgac ggatgcaggg gtgaaggccc gatttgtgct ggtaggtgat
    22741 ccggatcccg gcaatccggc ctcagtgccg gatacttccc tacgcgcctg gcatggtcag
    22801 cacggcattg agtggtgggg gcggcgcgaa gatatgcctg cggtcttgca actcgggcac
    22861 atcgcctgcc tgccttcgta ccgggaaggg ctgccgaagg tgctgttgga agcggcggcc
    22921 tgcggacttc cgctagtcac caccgatgct cctggatgtc gggatgtggt gcacgacggt
    22981 gacaatggct ttctggttcc catccgtaac gcgcaagctc tcgctctggc cctggccaga
    23041 ctcattgaag acgcagcgct ccgtgccaca atgggccgac gtgcccggga gattgtgttg
    23101 gcagagtttt ctcaagagcg gatcatcaag gagaccctgg ctgtttatct ggaactcacg
    23161 ccgtgaacgt cttggtgacc ggtgcatccg gctttgtggg acacgctgtc tgcgctcaac
    23221 tggtcgcgca gggcgtgact gtcactgccg cggtacggcg cccggcggcc cagccagtgc
    23281 gtggtctggc ctattgccag gttcgtgatc tgggccccga taccgactgg cacgaggctc
    23341 tgactggagt gcatgtgatc gtgcactgcg cggcgcgcgt gcatgtcatg caagaaaccg
    23401 acgcagatcc gttgccagca tttcgcacgg ccaatgtctg cggtacggtc gctctcgcgc
    23461 gtcaggcggc ggaactgggg gtagagcggc taatctacgt gagctctgtg aaggtcaatg
    23521 gagagggcgg acaggacgcg taccgcgaaa ccgatgtgcc ggcaccccag gacgcctacg
    23581 gggtgagcaa gtacgaggcg gaggtcggtt tgcgggagat agccgcgcat accgccctca
    23641 aggtggtggt cgtgcggccg cctctcgtct acgggccagg agtaagggcc aattttcagt
    23701 tgttgatgca agcgctggcc cgtggtattc ccttgccgct aggagcgatc cgtaaccgcc
    23761 gcagtctagt ggggttgggg aatctcgttg atttcatcgt cacttgcatc gagcacccac
    23821 gcgctgccaa tgagatattc ttcgtgagcg atggtgagga tctctccacg acagaattga
    23881 ttgatcggct ggcccttgcc atgaatcgtc cggcacgact cattccggtt cccatgccag
    23941 cattgagatc gggattaact ctgctcggtc agcgagagat ggctgctcgt ctctgcggga
    24001 atctacgagt gaatattaca aaagcgcgta ccttgctggg gtggtgcccc ccgatacgtg
    24061 tcgacgagga attgcgccga gcggcggaat attatcttca gcatcaatag tgatgctggc
    24121 tgactctgga aggaatcgag aagtggcgct gttaggagtc ggtggcctcg tgcttgtctt
    24181 gacgtactgg ggaatcggtt ggttgtgcat gcccggttct cgtctttatc tgttggacta
    24241 ccccaatgcg cgatcactgc atgagattcc cacgccacgc acaggcggcc tcgcgctcct
    24301 tgttagcgcg gccatcgggt tgatagtagc aaccctctgg gaatttccta cccaggcatg
    24361 gtggttaagc gcctcgcaga cttccccaac ggcaggggcg tggattttgg ccatgacagt
    24421 tctgctggca gtggtgtcgt tctgggacga ccgtgacgga ttgcctgtgc tccttcggtt
    24481 agccgttcaa ctgattgccg ccgcgacagt cgtcatcgga gctggcgttt cattgtcgtc
    24541 tctgtccctg cctgctgtcg gtagcctctc cttcgagggc gttgcggtcc ccctgactct
    24601 cttgtttgtc ctttggatga cgaatcttta caattttatg gatggaatgg acggatttgc
    24661 gggcgggatg accgtgtttg gatttggtgc gatagcctac tttgcctggc aggcacaaca
    24721 tccattcatt ctcattcttt ccctcattat ttcgatggga gccgtcgggt ttcttctcta
    24781 taatcttcct ccagcgcgca ttttcatggg ggatgtcggc agtatttcgc tcggcttttt
    24841 aagcggcaca ttgagtgtct tgggcgtgca ggatggcctg tttgatatct ggacgccact
    24901 cttggtgttt tcgccgtttg tgctggacgc aaccaccacc atgttggggc gggccgtgcg
    24961 cggagagaaa atttgggaag cccatcgaac ccactattac cagcggttgg ttctccacgg
    25021 gtggggacat cgaaaaacgc ttctgtcaga atatgcgctg atggcactgt gcgtggccgc
    25081 cgcagtgctt tatcacggag ccaccgattc ggggcggctt gcgattttgg tcgtctggat
    25141 actgggtttt gctgggttgg ctgtgggagt cggtctgatg gagcagcgtg ctgggcagca
    25201 ggggcgaatg tatgaagatt agtcggattc ccgctgtatg ggcctccatg gaagcaaatc
    25261 acggaccaac tctggatctg attgtccggg ccttgcttta tgtgtatatt ttctccctgc
    25321 cgttcctgcc actcttagtg gttgaacgca acatcttctt agtactcctg gtgctcctgc
    25381 cgctgtggtg cctacttcgt cgccgccact tttttgtgtc tagccccgtc gatttaccat
    25441 tgatcgcgtt tgttgcttgg gtggctttca cgattccctt ttcggcacat cctgcctata
    25501 gcatgaagga gtttggcaaa ctcctacagc aggtggtcat tttctatgcg gtgctgtatt
    25561 tcttcaggga gcgcaccgcg cgcgatcttc tgacgtatct tcttctcggg tgtgtgctgg
    25621 tggtgagtgc ctatggaatt acacagttcc agtggtatga cggtcaggct actcggtcat
    25681 ttttccctgc cgaggtgtgg ctgacaactt accttgtgct tctggggccg ctgtttttct
    25741 cacttgccta ctacgaagtc acgaatcgtc tccgctacgt gtatggatgc gggagcattt
    25801 tggtcacgat ctgtctgctg atgacccgat cacgtgcggg tttggtggcg ctgtttgtcg
    25861 aactgtgggt catggcctgg ttgctcaagc gtcgtagcgc agtgaccgtt gcgggtggtg
    25921 cgacggtagt atgcttgctc gctgccctgt ttctaattcg cgtggatacc ggttctgatg
    25981 gtcaacttcg tcttacttta cgggatggca ctccggttcg aactgatggc gcgtctgtga
    26041 ttcatcgttt cgatatttgg gcgtttgctt tgtcaaagat tcaggagcat tggtttgtgg
    26101 ggataggcta cggaaaagac aactacaagt tggtgtatgg agatgaacca gaagaggtgc
    26161 aacctgggca tcatcctgtg aagacggccg gcgcccacaa cattgtgctc gcgtcggcgc
    26221 tgcatgtcgg gctcatcggt atggtgttgt ttctgtggtt gtgggggaaa ctggttcgcc
    26281 gactcatcca ggaatgtcac cgaacggaag gctcgacagc tcgagccatt gtggtgggag
    26341 cgacggtcgg tgtgatcgga ctaggcgtgc ggctgatgtt tgatcagatg ctggtcggta
    26401 ctcttgcagt tcagttttgg gttgtggttg ggatcgcggt ccttcatgtt aactcacaac
    26461 gcgaatcgga cagggagggt gtagtggccg ctgtttcagg cgcggcaacc ctcgcgggtg
    26521 ctcgctcggg ataatctgag cggattgaga tcgatcggtt aatcactgac tgctgaaatc
    26581 tgtgtgaatc aggcatgaag cgcatagccg tccaggtgtt tcaaaaagtc tcctcgagat
    26641 ttggccagac aattcttgcc tatcgtacgg cattgataat ctgcgtccag gccgggttga
    26701 ttttggccgc caatttcacg gcctttgcct ttcgtttcga tgggcagatt cccgccctct
    26761 ataaggacac gatgtggaga ggtatgcctc tcgtgtgcgt cgtctatctg ctcggactgt
    26821 gggggttcgg tatccatcga ggtttgtggc ggtatgtcgg cttgcatgac ctcgggcgga
    26881 ttatgtgggc ctgtgtggtc agcacgattg tgacattcgt tctgttgcat ccgattttgg
    26941 gccgagtgga gtatccccgt tctgtcattc ttgggaccgg acttctggcc ggcctcaata
    27001 ttgccggtat tcgactgctt gtacggtggt ttcgagagtg gctgcaaatc gtgggaccta
    27061 cggctcgtcg cgtcttaatt gtgggggccg ggaacgccgg tgaattgctc gttcggaaca
    27121 tgcagatgaa ccccgcctac aactatcgcc cggtcgcgtt tgtggatgac gatccggtga
    27181 agcaaggagc caaaatccat ggggttccga ttgcgggttg cattcagaac atcagagaaa
    27241 tcgtgcgtcg ttttgaggtg cacgaaatcc tcatggccat cccttctgcg ccgctggcct
    27301 tgaagcaaaa aacgcttgct gccgtcgaag gcgcgaaggt gccaatcaag attcttccga
    27361 gcgtgcgaca gctgctggaa gatccagccc tgttgcagca ggttcggcca atgagcttag
    27421 aggatcttct ccagcgggag ccgattcaaa cggatcggca ggaactacac ccgttgatcg
    27481 agggaaaaac cgctttagtc actggtgcgg gggggtcaat tggatcggag ttatgccgac
    27541 aaattgcccg gtaccggccg gcaaccttgg tgctattcga acggtatgaa aatgccttgc
    27601 atgcattgtt gctggaactc caagcggcct ttcccgatgt ctgtattctt ccgatcgttg
    27661 ctgacgtgac aatgcctgag cgtgtggcag aggtgtttcg gcaaactcag ccagacattg
    27721 tgtttcatgc tgcggcgcat aagcacgttc cgttgatgga actgaatccc aaggaagccg
    27781 tgcggaacaa tgtctggggc actcgtgtgg tcgcggaggc ggcgttggcg tcgagggtcg
    27841 atcgcttcgt cttgatttct accgataagg ctgtcaatcc atcgagtgtg atgggcgcca
    27901 ccaagcggat cgcagaacat gtgattcaag ggctgagcca attgggacag acgcgattta
    27961 ccgttgttcg gtttgggaat gtattgggca gcaacggcag tgtggtgcca ttgtttgccg
    28021 agcaaatcag aaagggcggt ccggtcacgg tgacggatcg tgaaattaaa cgatttttta
    28081 tgaccattcc cgaagcagtt caacttgtcc tgcaggcgag tgtcatggga cagggggggg
    28141 aagtgtttgt cttagatatg ggggagcaaa taaaagtcgc ggatctcgcc aggaatatga
    28201 ttgtgttgtc cgggtttgtt ccggataaag atatcgaaat tgtctataca ggactccgcg
    28261 tgggagaaaa actgtacgaa gagttgttcg aagctgggga gcaggtcctg gcgaccgctc
    28321 atggtaagat taaccgggcg gttggggcgc cgctggtagc ggaagggttc gagcgatgga
    28381 tcgcagaact gcactcgaaa cttgcagaga gtgacgagga ggaattgctg catgatctca
    28441 aaagaattgt gcctacgttc cagccaacgt ctcctctacg agtttcttaa ttgatcagca
    28501 agcatcgatc gcatgccatt gagtgttctt gagtttcatg tgatggcttg ttaacatcgc
    28561 ccccgaaagc cttcgcatgc ctagcacaac acgtcgaacc agcactccat cgaagtcacc
    28621 tgcttccctt caagggattc tccggggcat tcgtttattc gcaacggatg tcgatggcgt
    28681 actgacggac gccggcatgt actactcaga atccggagac gaatggaaaa agttcaatac
    28741 gcgcgacggc atggggatca agctgttgca gaaggccgga atcgtcacgg cgatcattac
    28801 ccaagaatcg acaaaaatcg tcatgcgccg ggcgcaaaaa ttgacgattc ccgaggtgca
    28861 tcagggggcc tatgataagc tcgcagtgtt gaaggatctc atcgcgcggc atggcctcac
    28921 gatgaagcaa gttgcctaca tcggtgatga cgtgaacgac cttcaggcgc tgggtgcggt
    28981 cgggttctct gcgtcgccag cggatggcat gcctcccgtg ttgaaggtcg tacgctacgt
    29041 atgtaagaag aacggcgggc agggtgccgt gcgggaattg gcggatctca tactggcagc
    29101 ccaaaagtcc cagtgagaga acaacaaccg cgtcatgttg aacggaagcg gagtcgaaaa
    29161 aaatatgaca aatcacctct atccggttat tctggcgggc ggcagcggga ccaggttttg
    29221 gccattgagc cggcacctgt atcctaagca gctcctgcgc atcatcggcg acgagaccct
    29281 cattcagcag accatgcggc gcgtgctctc ctgtgccagc cccgatcggg tgctcatctc
    29341 gaccaatcca gggcaggccg actcgattcg cgtgcaatta ggggaatgga agtccgatct
    29401 caaggacaac tatgtcattg agccgatagg gcgcaacacc gcgccggcca ttgcgctggt
    29461 ggcggcggag ctccttcgac gcgatcccga ggcgatgatg ctggtgttgc cggcagatca
    29521 tgtcgtcacc ggggagaagg cgtttcaggc agcagtgacg ttggggatgc agcttgccga
    29581 gaagggacac ttggtgacct tcgggatcaa gccgaccagg ccggaaaccg ggtatggata
    29641 cattcaaccg aaccggcgaa ctaccttagc caagaaggac cggctgacag gtcacccggt
    29701 tgccagattt gtcgagaaac cgagtcggac caaggcggcg cagtatctca aaagtggcaa
    29761 ttacttctgg aacagcggga tgttcctctg gaaagccgcc acgattcgag acgagatcaa
    29821 tcgtcaccag ccgcagctgg cgaaagcggt gcagaaagtt cacaccctga tgacatcggg
    29881 cgccgatccc cggcagattg aagccgccta caagaaagtt ccttcggtct cgatcgacaa
    29941 cggcgtgatg gagttatcgt cgcatgcggc catgattccg gtggggttcg gctggtccga
    30001 tgtgggcaac tggagtagcc ttgaagaagt tgcgccgcgc gacaaggccg gtaatgtggt
    30061 cagcggtcga gttatcgata tggacagcag caattccgtc ctttacgccg atcgccgggt
    30121 cgtcgccacg attggcctca cggatatggt cgtcgtcgat acgccggatg caaccttgat
    30181 ctgtccgaaa tcccgctcgc aagacgtgaa gcagatggta gagatcctca agcaacaggg
    30241 ggcgcctgag catctggaac atgtgacggt gtttcgcccg tggggttcct atacggtctt
    30301 ggaagaaggg cctggatata aagtgaagcg tgtgacggtc aatccgggcg gccgattgtc
    30361 attgcagctt caccataagc ggagcgagca ctgggtggtg atcacaggga ctgctcgagt
    30421 gacccgcggc gacgacgtgc tgcatctcca gatcgggcag agcaccgcaa ttccggtcga
    30481 aactccccat cgcctcgaaa atccaggtac cgagacgctc cacattatcg aggtgcagaa
    30541 cgggccctat ctcggtgaag atgacatcgt gcggtttcag gacgattacg ggcgactcgg
    30601 ccgggcacgt taggagatgg catggcgctg tttcgcgaat atgatctcag aggcattgtc
    30661 ggagaagagc ttacggaacc cattgcggag caggtgggcc gggcctatgc cactatggcc
    30721 agggagcaag gggcctcgcg gatcagtgtg gggcgggatg ggcgcctgag ctcgcctgcg
    30781 ttgcagcagg ccttacttcg gggtctcctt gccggcgggc tcgatgtggt cgatttgggc
    30841 ctctgtgcat cgccgctgtt gtatttttcc ttgttcacgc ttccggtcca cggcggaatc
    30901 atgatcaccg gcagccacaa cgccgccgaa tacaacggct tcaagatctg catcgggaag
    30961 gaagcgatcc acggcgaaga gattcagcag ttgcggagca tcatggagcg cggccgattc
    31021 agttccggct ccgggcaact gtcctctcat cccatcattc cggactatct acagcatctc
    31081 aagacggtgt tcgcgggtgt ccgggcagat cacctgcatg tcgtcatcga ttgcggcaat
    31141 ggcgcggcct cgctagtcgc caagcaggcg ctggagcaga tgggctgtcg cgtgaccggg
    31201 ctctatgatg agttggacgg gcgttttccg aaccaccatc ccgatcctac cgtcgtggag
    31261 aatcttcaag atctgattgc caccgtacgg gaacacaagg cggatgtcgg gatcgggtac
    31321 gacggagatg ccgatcgcat cggcgcgatc gacgagcggg gagagatcct ctggggggat
    31381 cgcctcatga tcgtgtacgc gcgcgatatt ctcgctcaga ggcccggtac taccttcatt
    31441 tctgaggtca aggcctcgca atgcttgtac gacgatatcg cggccaaagg cggacgtccg
    31501 atcatgtgga aaaccggcca ttcgctgatg aaggcgaaat taaaggctga atcagccgtc
    31561 ctcgcaggcg aaatgtccgg ccatatgttt tttgccgatc ggtacttcgg gtttgacgac
    31621 gcgatctacg cttcctgccg gttagtcgag attctggcaa agaccaaaca ctcgctctcg
    31681 agtctggtgg ccgatctccc gcagactaca gtgacaccgg aaattcgagt ggattgtccc
    31741 gacaccgtga agtttcaatt ggtcgaacag gtgcatcggc agttagcctc ctatctcgag
    31801 gccggccagc cggtcggcgc gtcgaatctc cggatgcggg aattggtgac gatcgacggc
    31861 gttcgcgcga ttttcgagga tggatggggg ttgatccgcg cctcgaacac ccaaccggca
    31921 ttggtcctcc ggtttgaggc gccttcgccg gccaggttgg acgtgatccg cgcgaccatc
    31981 gaaaccgaac tggcgcaggc gcggcgtgtg ttgtcggtct agggtgacca tcctccgatt
    32041 ccctctctct tccactcttc tgtttgtcgc ggccattgtg gccggcatcc ttctcccatc
    32101 gatgctgtgt gcggaatcaa ccccggacag acggccatcg gtttctgcgc cgctgccctt
    32161 tgccaacggt gagcgtctcg cctacgacgt aacctggctg gggatgcggg cgggcattgc
    32221 cacgatgatc gtccaggaag gacttgacca gcgcggccgg cggcagctca ccttgagcat
    32281 gactgcacga tcgagcccga ccgtgacgaa gttttatccc gtcgacaatc gcggggtctc
    32341 acaggtggat ctcgactcat tcctgccgac ccacatgacc tttgcccgcc gggagggaaa
    32401 acggtttaac gatttcgact ataccttccg gcatcacgaa ggcctggtga cggccgtgag
    32461 ggacggcaaa accgacgagc tgcagatacc gccggatgcg caggacgcga tgtcctgtct
    32521 gtactatgtc cgcaacgtct tgccgttcgt gccgggggaa accctgacga tgacggtcca
    32581 tcacgacaaa aagaattaca aaatggacgt gcgcgtcgaa gcccttgaaa ccgtggaggg
    32641 ccggtggggc aaggcggaaa cggcccgcgt ggtggtgatc atgccgtttc agggtatttt
    32701 tctgaacgaa ggtaatatcc gggtctggtt taccaccgat ccgcaccggg tgcctgtgcg
    32761 gatgaaggcg aaggtcgtag tagggtctat tgtggctgaa ttgacggagg gctacgggtt
    32821 ggccgcgcag ccataatctg ccggcctggt ttgctcgctc ggccggaaac cgctataatc
    32881 gcgccaggtt cgtggggagg gcttcggctc tgtccgaagc cctcgtcatt tcgactcgtc
    32941 gtcgttcaat ccatgaggac tcctcagcat ggcgaaattc cccattacgt taagccgctt
    33001 tatcatcgaa caacaggccg cgcatcctga agcgaccggc gaattttccg tccttctgac
    33061 tcaaatcggt ctcgtcggta aaatgatcgc tcatgacttg cgtcgtgccg gattgaacaa
    33121 gatcctgggc acgaccggtg agaccaatgt ccaaggcgag atcgtcaaga agctggatca
    33181 gatcgccaac gatacctttg ttcgcgtgtt tgaacacagc ggcctcgtct gcgtcctggc
    33241 ctccgaagag atggaaaagc cgctgaagat ggtccacgaa ggcgcgaagt acatgttatt
    33301 ggtcgatccc ttggacggct cctccaatac cgatgtcaat atgccgctcg gggcgatttt
    33361 ttccatccgc cgatcgcgga cgggacaatc cgtcgaagat gagttgttgc aaaagggaac
    33421 agagcagatc gccgcggggt atgtgttgta tggggccagc acgatgctcg tgttcacggt
    33481 cgggcagggt gtccatggct ttacgctcga accgtccatc ggtgagtatc tcctgtccaa
    33541 tgagaacatc cgcattcctt cgaagggcaa ggtctattca gtgaacgagg ggaattatca
    33601 tcgctggcct gccggcacac agcggtatct cgattatctg aaagtgcagg ataagccgtc
    33661 cgggcgcccc tatagcgggc gatacagcgg gtgtttggtg gcggatgtgc atcggattct
    33721 cctgggcggc ggcatctatc tgtatccggg agagaaggat aagcctgagg gaaaactgcg
    33781 attgatgtac gaaggcaatc cgttggccat ggtggtcgaa caggccggag gcaaagcgtt
    33841 gaccgggacg atgcgcattc tcgatgtcga gcccaaggcg ctgcatcaac gggttcccct
    33901 cattatcggc agtgctgagg atgtcagtct ggcggaagac tatgtgcaag gacgtgcgta
    33961 acgactaatg tgatcgaggt tggttgggag gttgattatg agcaatcggg tccaggaaat
    34021 tctgagctgg tatgagagtg acaacgcggg aacaaagacg aacatcgccc ggttgctgaa
    34081 ttcggggaaa ctcgccggaa ccggaaagtt ggtgatcctg ccggtcgatc aagggtttga
    34141 gcatggtccg gcgagaagtt ttgcgcccaa tccgggcggc tatgatcccc attaccactt
    34201 tcaactggcc atcgacgccg gatgcaacgc ctacgcggcg ccgctcggat ttatcgaggc
    34261 cggtgccagc cacttcgccg gcagaattcc actcattctc aaattgaata atcatgatgt
    34321 gctgcacgat gagaaggatc cgctgccctc ggtgacaggc agcgtgcagg aggccttgcg
    34381 gctgggatgt tcagccgtgg ggttcacgat ttatcccggc tcttctcact gcaatcccat
    34441 gtatgagcag ctgcgcgtga ttgcggagga agccaaaaat gccgggctgg ctgtggtggt
    34501 ctggtcgtac ccgcgcgggt cagggctgag caaggaaggt gagacggccc tcgacgtggt
    34561 ggcctatgcc gcgcagattg ccgcgcaact cggcgcgcat atcatcaagg tcaaattgcc
    34621 ctcagcccat ttggagcagg cagcggcgaa gaaggtgtat gaggccgaaa agattcccac
    34681 ggcgacgctg acggagcgcg taaagcatat cgtgcagagt tcgttcaacg ggcgtcgcat
    34741 cgtcattttc tccggcggtg cgaagagcga cgaaaaaacg gtcttcgaag aagtgcgggc
    34801 gatccgtgat ggcggaggat tcgggtcgat catcggccgg aattcattcc agcggccgaa
    34861 ggcggaagcc gtgaaatttt tgaacacgat catgagtctg tacgcgggcg agaagcccta
    34921 gtcggtccag actgacgaac cactatggat gacggtccga ttccacctga acagcgacag
    34981 tcgatgcgat cctggatctt tccagcattg ctgttatcag caggcatcct gatcgggatt
    35041 gtcctgacct ccgatctggg atggttaccg acaggacatg ccgtgccgga ggcgcctgcc
    35101 gtgccagctc cggttcccag gccggtttca acggcagtgc aaccgacgct gcccggcgcc
    35161 ggggggcaga gcttcgtcga cgtcgccaag atcgtcaaac ccgcggttgt gaatattttc
    35221 gcaactcgca atgggggcgg cgaagaaggc aagggtacac cgttcgagga tccctttttt
    35281 cgacgcttct tcggcgagga gtggatgaag cgctttgaag cgccgaagga gcggaaacag
    35341 caggggttag gttccggcgt gatcgtcgat gccaacgggt tgatcattac gaacaaccat
    35401 gtggtgaata aggccgacga gatcaaggtg tttttgtcgg acaagcggga gttcaaagcg
    35461 aagctcgtcg ggacggatgc gaagaccgat gtcgccgtcc tgaaaatcga ggcgaccggc
    35521 ctgccgaccg tggcatgggc cgattcggac aagctggaag tcggcgaatt cgtgctggca
    35581 gtgggcaatc ctttcggtct gactcagacc gtcaccctgg gcatcgtgag cgcgctgggg
    35641 cgcgcggcag gaatcgccga atacgaagac ttcatccaga cggatgcggc catcaatccg
    35701 ggaaattccg ggggcgcgct cgtcaacgtg cgcggggagt tggtcggcat caataccgcc
    35761 atctacagtc aaagcggcgg aaacatggga atcggattcg cggtgccgag caacatggcc
    35821 cattccatca tggaccagct ggttcagcat ggcaaagtcg tgcgcggctg gttgggcgtt
    35881 tccattcaag agttgacgcc tgaattgtcc tcgcagttcg gggtgccgaa agaggtgaaa
    35941 ggcgtcctcg tcagcgacat catggatgat agtccggcga aaaaggccgg gttcgagcgt
    36001 ggagatgtga ttgtcgaata tgacggcaag ccgatggatt cgccggccca cttacgaaat
    36061 gccgtggctc agaccgtggt cgggaaaaaa gtcacggtga agctcattcg tgagaagaaa
    36121 ccgaagtcca tcgacctggt cattgccgag cagccgaaga atctgtcgca ggccgctgca
    36181 gaagaaggcg gggagtccat tgcgccagcc ggactgctcg cggatatcga agtgcgggag
    36241 gtgaattcag agttagccgg ccgatatggg ctcaagtcca gcgaccgcgg aattgtggtg
    36301 gtccgggtca agccgggcag tcaggcggaa gaggccggtg tgcgcgaagg cgaccttgtg
    36361 ttggaggtga atcgcaagtc ggtgggcacg ctcaagtcgt acgaacatgt ggccgcaaat
    36421 ttgccaaaag accaggcggt cttgctcctg ttgaagcgac aggggcgggc catttatctg
    36481 acgctgaggc cgtgattgct tcgagtcgtt gattcgaggc tgatcacaga gaggaggaaa
    36541 acagtatggt aacacgggcc atatttgttc ttctcagcgc tcttgcgggg ctggccttgt
    36601 ttctgcgggc ccaggatccc agtcagggat tcctgctggt agggttgggc atgggggccg
    36661 tagctggtgg actaatcctc gccggggaat atgccctccg gaggctgtca ttcggtatta
    36721 ttgtcggtgg agccgttggg cttgccggtg gtttggtgct gacggggttg gttgagtggg
    36781 tcggcagcgc ggtctttgac gtcgagacat ttttatttca catcggtggc ttggtgtttc
    36841 tgctgggatt tccttatctc gggttagcga tgggagcgcg gttcggccag gaacaatttc
    36901 ccggggttca tccggggcag tcgtcaggat cctcccaggc atgcctcaag gtgctggaca
    36961 ctagtgtgat catcgacggt cgggtagcgg acctctgcga aacgggattt ctcgaggggc
    37021 cttttctggt gcctcatttt attttgaatg aattgcaaca cattgcggac tcatccgatt
    37081 cgttgaaacg tgcacgcggg cggcgagggt tggatatcct gaacaagatt caaaaaatgc
    37141 ccgaagtcga tgtgcgtatc atcgaggaag attttcctca cgtcaaagaa gtcgatgcca
    37201 aactggtggt gttggccaaa aaagtggggg gccgcattgt caccaatgac ttgaatctga
    37261 ataaagtcgc cgaattgcaa ggcgtgcgcg tgttgaatat caatgagctg tgtaacgcct
    37321 tacggccggt ggtcttgccg ggtgaaacca ttcgcgtctt cgtgttgaag gaaggcaaag
    37381 aagccggcca gggcgtggcg tacctggatg acggcacgat gatcgtcgtc gacaatgcgc
    37441 ggcgctgtat cggacgcaat gtggatgtca cggtcaccag tgtgctccaa acgacggcag
    37501 ggcggatgat cttcactcgc ctgaaagagg agtccgaacg cgaagaatat caggtcgcgc
    37561 gtggttagcc cgctgatgag caggcgcggt agcctcgccc cttccggggg ccggcgcctg
    37621 cgcatgaggt cgtggattcg gttggcaggt tgcgctgtgt tcttgttctg tgagtcaatc
    37681 cgtgtcggtt cctgagtcga aatcgtcacc gacgggattg agaacagtgg cccttgttcc
    37741 ggcggctggt cgtggccttc gcatgggcgg atcagtccct aagcagtttc tcgccctggg
    37801 cggacggccg attctggcgc agtctcttca cgtcctccaa gcctctccgg tcattcatga
    37861 gatcattttg gccgtgccgc aagcggaccg ccaatattgt ctggatcact ttgtggcgcc
    37921 cggagaattc gggaaggtca ccaaggtcgt gtccggcgga gcgcaacggc aggattcggt
    37981 tcgtcatgcg ttggccgagg tgagtgaggc ggatattatt ctcgtgcacg atgcggtgcg
    38041 gccgtttctg accggggaca tgatacgccg tgtggttgac gcggcggcgg agcatggagc
    38101 ggccatcatt gcacttccga tgcgggatac ggtgaaatat gtcggggccg gcggcgtgat
    38161 cgagcggacc atcgatcgcg gtcccttgtg gcttgcgcaa accccgcagg ccttccggcg
    38221 tgcctgcctc gaggaggcgc atcggaaggc gctgctcggc aacatccatg cgacggatga
    38281 cgcgcatctc gtcgagttgt tggggaagcc ggtcgtggtg gtcgagggaa gcggtgaaaa
    38341 tatcaaggtg acaaggccgg aagatctcgt gatcggcgag gcgattctcc aatcacgaac
    38401 agcaacgagg agtgcagaat gacgggtgta cgcgtggggt gtgggtggga tattcatccc
    38461 ttggtggccg gacgcaagct gatcctgggc ggactcgaaa ttccgcatca ccaggggctg
    38521 cagggacatt ccgattccga tgcgctcgtg catgcgatct gcgatgccct gttgggggcg
    38581 atgggagaag gagatctggg ccgccactat ccgagctcgg atcagcggtt caagaatatc
    38641 tccagcttga agttgctcga agacgtcgtg ggcaaattgc gggcaaaagg ctatcgtctt
    38701 gcgaatgtcg atagcaccat cattgcccag gcgcctcgct tgagcccgca tttggccgcg
    38761 atgcaaaagt cgattgccgg ggtgctgcaa atcgatcccg atctggtgaa tgtgaaagtg
    38821 aagagtggtg aagggctgga tgcggtgggt cgcgaagaag cgatcgccgc gcaagccgtc
    38881 tgtctgatcg agcgtgactg agttgtaagg cggatgacgc gcgtacggct atcccagcta
    38941 tgttaaaggc cattgctcaa gacctccagg cgattttcga ccgggatcct gccgcgacga
    39001 gcaggctcga ggtcattttg acctatgcgg gattccacgc attgctggcc taccggcttg
    39061 cgcattggtt gaaacagcat caagtgccgt tcttaccgcg cgccgtgtca caactggcgc
    39121 gttggctgac cggaatcgaa atccatccct ctgccaaaat cggtgcctcc ttctttatcg
    39181 atcacggcat gggtgtggtg atcggtgaaa ctgcggaagt cggcgaccat gtcaccttgt
    39241 ttcagggcgt gacgctgggc ggcacaggca aagagcgggg caagcgccat cccacgctgg
    39301 ggaatcatgt ggtggtcggg gcgggtgcaa agattctcgg cggcatcacc atcggcgaca
    39361 atgtgaaaat cggcgccaat tcggtcgtcg tcaaatcggt tccgccgaac tcgaccgtca
    39421 ttggagtgcc ggccaggatc atcaaatcac aaggcgagcg gcttcccgac gccacgatgg
    39481 atcataccaa tatgccggat cctacagcag accgcttcgc cgcgctggag atggaactca
    39541 tcgagttacg aaagaaactc gaaaaccagg acaccggtaa gccccgctaa cccgccgcga
    39601 cgctcgttcc tctattgatg tgcgattgga gacaggtacc acgccgactg cttcggcgaa
    39661 gacgggatgt tgtgtgggtg atcgatgaac cccggcacag cctagtacca tgccggggtc
    39721 gctgcggtta gttggacagg cattccttca taaacttctt ccgttcatcg ccggccagat
    39781 tctttgcctt ggcatcctta ttacaggtct tcatcttgtt ctgctgagac gccccggctg
    39841 cggctttttc cggcttggcg gagagacatt ctttcatgaa tgccttgcgc tgctcgcctt
    39901 tgccttcccc gctgagcccc ttggcatccg catcggcatt gcaggtcttc attttgttct
    39961 gttgtgctcc ggcatagctg agttgcggcg tgacgagcac ggctgccaac acgatcgagg
    40021 acaagactgc gcaaagatgt ttcatggaag tctcctgttg aggtggacgg gggatgtcgg
    40081 cggaactata gcaaaaattg ccggttctgt ctcacgggac agttacctag gtgacaggag
    40141 gagcggatgc cgcgtcataa tccactctga cgagatacaa cccatggggc ggggccgtcc
    40201 tcccggctgc agggcgggag cgggccttga gaattgtgtc catatcggac gccgatcgtt
    40261 tgccgcgtcc tacgtccacc agcgtcccca cgagactgcg caccatctgt ttgaggaaac
    40321 ggtcggcata gaaggagcac acgatgagat cgccctcccg gcggagtgcc gattgctgca
    40381 tgcgacagtg cggattgtca ttgtcggtgg gcgcggtttc aaacgaggag aaatcgtgcg
    40441 agccgagcag gacggctgcg gcatcggcca tcgcggcgac attgagtggt tggtaaacag
    40501 accaggctcg ttcccgcagc agagccgccc gctccgatcg attcaggatg tggtactcgt
    40561 agagtttgcc ggtggccgaa tatcgggcgt gaaaatgctc cggcacggca tcgaccgaca
    40621 acgcgctgat gtctgagggg agatgggcat tcaaggcgcg aagccactct cgtggcgaaa
    40681 ggccgcgatc ggttttgaag ctcgccacct gcccgagggc atgcacgccg gcatccgtgc
    40741 gacctgcccc aaccacggta agcctcgttt gcgagatcgc cgcaagcgcc gcttccactg
    40801 cagcctgaac ggtcgatgca ttcagttggc gttgccagcc tgagtaacgg gttccatcgt
    40861 actcgagaac gagcttgaac gtggtcatca tgtgagtgcg aaaagcagca ctctagctta
    40921 acgggaaggc ggctgtcatc gggagggatt ggtgcggagg tatgtcttga ccccttcgaa
    40981 gatcgattcc gcgatatgcg ccaggaacgg ttgcgtgcgc atctgttcct cttccgccgg
    41041 attcgacatg aaggcgattt ccgcgagaat gctgggcatg gtcgtaaacc gcaggacata
    41101 aaacggcgcg gtcttcacgc catgatcgat ggtgctatac cgaccattga gattggtgac
    41161 catcgcctgt ttggccgtcc aggccagttc ttgtgaatgc tcgattttct tggtcgtcag
    41221 aagatctgca aggatgtact ccacgccgag tccagtgctg tttaacggcg tgccgttttc
    41281 ccgagccgcg acttccagcg cccgctgatc cttggcttcg ccgaagtggt agatctccaa
    41341 gccgcgcacc cccttatgcg ggtgcgagtt gacgtgaatg gacacgaaga gatcggcatt
    41401 tttgccgttg gcaaacttgg cccgatcctc caactcgatg aacgcatcct tctcgcgagt
    41461 catgagcacg cgtgtattgg gcaaggtact caagaggtcc ttcaacaaca tgccgacttt
    41521 gagtgtgaca tctttttccg tcgtcccatg ttgtccgatg gtgccggggt cttttccccc
    41581 atggccggga tcgatcacga tcgtctgaat ctgactggca ggtttaggcg ccacggggcg
    41641 aaccggttcc gtcaccgtgg ggctgggaat cgtcggcgga gtcgggaggg ccacggcagg
    41701 ggctgatggc gacgtcgagg acgtctcgcc gatctgccgg atctgatctt tggccttgtg
    41761 gtagatgtcg atgacgaggc ggtccggatt gtccagggca aacgctttgt acttcgagcc
    41821 ctgggtgcgc gcgagggtga tggtgacgac ccgcggacga ctttgcgtaa tgtgaaacga
    41881 ttgcggaatc gtgccgccgg agacacgctg ccgggaggac tttcccagaa tcgcattact
    41941 gatgtctatg acgacccgat cgggatttcg cacgtgggtt tcggtgaagg aggctttgtg
    42001 attcaggtcg agcaccaggc gtgtgccgtc cggagtggac caggtacgca ggtcgcggac
    42061 gatgatcgga taccgcgagg tgccggcgga atcttgtttg atcagcagga attgaggtgc
    42121 cgctgcgtcc ccggacggct ggggaatctg gggccaggat ggctcggacg gcatctccgc
    42181 gctggacagg gaagccgaac cagccaggaa ccagccgagg gtcagcagga ggcaaagacg
    42241 gaacagccaa ttcatccgag gaacgagtcg gaacgcttct cgacaaggta ccatctaggc
    42301 cttttctcag atgtttatgg tattgtcaac aaaaggtctc aaactgcgta attgtagatg
    42361 gcgacacatc ttcttgtcga tggatataac ctgttgggaa gcgcgcgcat ggcgggtcca
    42421 gccggtcccg gccgcctcga agcggcgcgc gacggcctgc tccatgccct ggcaggctac
    42481 cgtcagcgca aggggcatgc gatcacggtg gtgttcgatg gatggcaggg aggactgggc
    42541 gccgaacagc gcgagtttca atcaggcgtc gaggtggtct attccaagcg gggcgaacgc
    42601 gccgaccagg tgatcgagcg tctggcacga ttgtatggca gggattgcgc ggtggtgtca
    42661 tcggatcatg aagtgatcaa tgcggcaagg gccgccgggg ccttcgtgat cggtgcgccg
    42721 gacttccgcg cgaagctgta tcagaagccg acgcgccacc agggtccggc attcaaagaa
    42781 ttggatcggg gcgaggctga ggtcgtgaaa cgatcaaagg acaagggcgg gaatccccgc
    42841 aagctcccca agtctcagcg caagcggaac cagcaactca gggaattttg aagaggcggc
    42901 gcgcattgtc gctggtgagg cggccgatgt catccgccgt cagcgtgtcg ccattggacg
    42961 tgatcgtggc caacgtttcg gcgacgtgtt tgacgtaagc cggctcgttg cgtttgcctc
    43021 gatggggaat cggggtgagg tagggacaat cggtttcgat gagcagccgg tcagccggga
    43081 cggtcttggc aatgtcccgc agcatggtcg cattctgaaa cgtcagaatg ccggaaaatg
    43141 acaggtagaa tcccaactcc agcgcatcct tcgccagcca ggcgtctccg gaaaagcagt
    43201 gaaatacccc gccgatctct gacgcccgct cttccttcaa gatgcgaatg gtatcgtcct
    43261 gcgcttcccg agtgtggatg atgacgggga gcttcaattc ccgggcgagt tgaatctgtt
    43321 cacggaatcg gaggcgttgc tcatccggat tggagtggtt gtagtggtaa tcgaggccga
    43381 tctcgccata ggccacgacc ttgtgctctc gcgccaattg ccgcagttcg tcataccagc
    43441 tgtccgtgat gtgtttgacc tcgtgcggat ggacgccgat cgaggcatac acgaaagggt
    43501 actgaccggc gagggcaacc gccgatcggc ttgtcgcgag atcacagccg atcgtgatca
    43561 tcgtctccac acccgcttcc cttgctctgg caatcatcgc gtcgcggtcg gaggcgtacc
    43621 gcgcatcgtc gagatgggta tgggtatcga tcaacatcga gtggattccg gcatccggct
    43681 gtgacagtgg aaatcgaagt gacagggcga tgtgagccta gactgtcttg gctgagaggg
    43741 attcagccat accgtagagc aactcttcgg tgtcgctcca ggcgagacag gaatcggtaa
    43801 tcgacatgcc gtacgtcaaa gttttgttcg gatcccagtt ctgccggccg cctt
//
LOCUS       DAOQPD010000025        42686 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_360_length_42686_cov_24.647580, whole genome shotgun sequence.
ACCESSION   DAOQPD010000025 DAOQPD010000000
VERSION     DAOQPD010000025.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 42686)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 42686)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42686
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_360_length_42686_cov_24.647580"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..200)
                     /locus_tag="PK063_07995"
     CDS             complement(<1..200)
                     /locus_tag="PK063_07995"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97029.1"
                     /translation="MHGTHREREELKSLVQAGREEGEKLHKYVKMVGRNDQRLLERYL
                     MDYIVPMVGAAGFEPTTPRTPS"
     gene            212..1027
                     /gene="surE"
                     /locus_tag="PK063_08000"
     CDS             212..1027
                     /gene="surE"
                     /locus_tag="PK063_08000"
                     /EC_number="3.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008252 - nucleotidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'/3'-nucleotidase SurE"
                     /protein_id="HMZ97030.1"
                     /translation="MARVRILVTNDDGIASPGIHAVAAALGTLGEVWIVAPDRERTAV
                     GHAVTLHKPLRITKMAPRVFMVNGTPVDCVNLALVKILPGPPALILSGINRGVNLGDD
                     VMYSGTVSGALEGTILGIPSVAVSQEGGETFRFEVGARYATRVAAQVLQHGLPAETIL
                     NVNIPDVPFRSIKGVKVTCLSRRRFNNPIVEKVDPRGRKYYWIAGTRQSWSRQQDADH
                     EALERRMVSVTPIHLDTTYHAMLEHFKAWEQPLSKLAASRRVVKARSSRRTRA"
     gene            1024..1659
                     /locus_tag="PK063_08005"
     CDS             1024..1659
                     /locus_tag="PK063_08005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HMZ97031.1"
                     /translation="MSALIEWLIEVLGRFVIATISTFGYTGIVLTMAIESACIPLPSE
                     IIMPFSGYLVFTGQFSMVGVTLAGAIGNVLGSLVAYYVGVWGGRPFVERYGRYFLVSS
                     HDMELADRWFAKHGEAAVLIGRLLPVVRTFISLPAGISRMDVKKFVVYSFVGALPFCY
                     ALAYVGLKMGEHWNELHQYFHHADLVIGVLLAMGLGYFLWSHWPRRRTSME"
     gene            1669..3129
                     /gene="cysS"
                     /locus_tag="PK063_08010"
     CDS             1669..3129
                     /gene="cysS"
                     /locus_tag="PK063_08010"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HMZ97032.1"
                     /translation="MLRIYNTLTGSKEPFESMVPGKVRMYVCGVTVYDYCHIGHARSA
                     LVFDVLRRYLEYSGFAVEFAKNFTDVDDKIIKRANEQGVSCDQITATYIKAYYDDMER
                     LGVRRATLEPRATEHIADIVALVDTLVAKGMAYRVNGDVYFQVDRYPGYGRLSKRNTD
                     DLQAGARVDVDERKRHPMDFALWKGSKPGEPSWNSPWGPGRPGWHIECSAMAMRHLGE
                     TFDIHGGGMDLIFPHHENEIAQSCGATGKEFARYWVHNGFVQINQEKMSKSLGNFFTI
                     REIFDKSEWPDAVTGEMLRYFLLSTHYRGPLDFSDQSLAEAKNALNGLYDLFERLKEP
                     APSHGAADQQMREASIRTRQAFADAMDDDVNTPNAVAALQKLRGDANKALDAGLSAEM
                     RHAVRNEFRSLGVVLGLFQQDSWQFKSPGSRETQGASGVSAKSLSDEEVADKIAARLA
                     AKQSKNYKLADELRAELASHGIIIEDRPDGTSRWKR"
     gene            3104..3886
                     /gene="rlmB"
                     /locus_tag="PK063_08015"
     CDS             3104..3886
                     /gene="rlmB"
                     /locus_tag="PK063_08015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HMZ97033.1"
                     /translation="MAPVDGKDNTPDVIYGLHAVREALRAGARPIQRLLVLGTDRQFG
                     EIVRLAREQRIPVYVEPRAAFDRLVPSGHHQGVVGLVAAKSYSDPDAILASAQAPGQT
                     PLLVLLDGVEDPHNLGAIVRTAEASGVQGVFIPERRAVGLTSVVAKASAGAVDYMPVG
                     RVPNLSRWIERLQQAGIWVYALDAEAPKVYTKLDFRGPVALVFGGEGKGVRPGVRGAC
                     DDAAHIPMSGKVSSLNVSASAAIVLYEAVRQRRERGEDRVGH"
     gene            complement(3897..4181)
                     /locus_tag="PK063_08020"
     CDS             complement(3897..4181)
                     /locus_tag="PK063_08020"
                     /inference="COORDINATES: protein motif:HMM:NF012422.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="HMZ97034.1"
                     /translation="MPTAARTTKGRTKAASSEPILPPRKRRPEALTTREQEILELIWT
                     GFKNKEIAQRLKISVKTVEAHRANMMKKIRVSNTAQLLKAAIQGKMLKLR"
     gene            4386..5174
                     /locus_tag="PK063_08025"
     CDS             4386..5174
                     /locus_tag="PK063_08025"
                     /inference="COORDINATES: protein motif:HMM:NF013632.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HMZ97035.1"
                     /translation="MAGGVMIPYVMVFLFGAVIGSFLNVCIYRLPREESVAWPASHCP
                     ACRQPVAVYDNIPVVSYLLLRGRCRSCQVPISTQYPLVEAVNTIGYVLIFWMFDFTAE
                     AFVYSALLSALIVITGTDLSHTMIPDAVTLPGIAIGLICAAVILPIGLIDSLLGVLAG
                     GGILWFLAWVSPYVFGKEGMGGGDIKLMAMVGAFIGWQPVLLAIMIGSFLGSLVGVAL
                     IAAGLTKRDQYIPFGPFLAAGSLLALLFHQPLLNWYWSLISLPQ"
     assembly_gap    5263..5362
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <5363..5662
                     /locus_tag="PK063_08030"
     CDS             <5363..5662
                     /locus_tag="PK063_08030"
                     /inference="COORDINATES: protein motif:HMM:NF023444.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GspH/FimT family protein"
                     /protein_id="HMZ97036.1"
                     /translation="ASELRMARQLAMARHERVRVVVNAAQSELRTECVDCETTVLRRY
                     EFARTGTVVDSMSTRPEILFQSSGRSATATTVVLIDSRRVTHQVTVSLTGRVSLS"
     gene            5659..6186
                     /locus_tag="PK063_08035"
     CDS             5659..6186
                     /locus_tag="PK063_08035"
                     /inference="COORDINATES: protein motif:HMM:TIGR02532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HMZ97037.1"
                     /translation="MKQPEGKRATRQGLTTSTAGFTLVESMVALVVLSIGVIGTIAMC
                     EWAQRGLQRGAMTTTALALAESCLEAKRSLPWDQLLVDDLDQNGTLESLMRDDGLLDD
                     ETNGDGIFTGSVTRSNIRLVWTVELNRGGQPGTASLATIEARASFTTLGGQSREVRVR
                     TIRANPRAVGAMALS"
     gene            6183..6956
                     /locus_tag="PK063_08040"
     CDS             6183..6956
                     /locus_tag="PK063_08040"
                     /inference="COORDINATES: protein motif:HMM:NF019575.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HMZ97038.1"
                     /translation="MTPATLSDSQQTKPIRARWCLNTRGVSLIELLIALAISSVAIAA
                     AIQTSAAYGSRLSSQHATMTANQELRLGLDVLCSELRLAGGGLLSGDTVFSKMEVDEV
                     EFFANLNGSSTILTQIVEVGRQDLPVEDGADWPKGKQLLLCTAAHCVWNRLAADGRKQ
                     TLTLMTPTLEQYQPKTAIFLLNRVRYYLKRAEGTHRLMREVDGVASTLLSELSGMQLQ
                     YFNKSGGIANDARDVVRVRVTIQGARQGMNLSRDIAIRM"
     gene            7038..8471
                     /locus_tag="PK063_08045"
     CDS             7038..8471
                     /locus_tag="PK063_08045"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97039.1"
                     /translation="MALLAVLMVVFLLTLLGMTSMQLAGQEVVGASALQEERLAHHAA
                     EAAVDVVMGWFHDPTLRPQEIGTTWFSKRLVNAQGDPSYVDAQGHGQFIGTSTAPDVV
                     FDAANIQHDRLLNDPQTGWFKSLKGLAKILKLRVYGATRPGLLCTVEVTAGAGPASRV
                     TKTLSLEFGAYAVPALHAPLQSGTLGSEAVQSRSGSVFTHWGEMVVRGRAYLPRPEDV
                     PVKSALAPVSGQVYDEMSHREDRWLTIRLGGDAFFAQLPAEAWSGVPLNVHAHQEPVP
                     GIKVDQWEYATLKRMAMQFGQVYGIDREGLLYAGGVIQAGMGRPASEVFASKGPGDHR
                     GLVFVDTLDGMPPRFDNLGTIVLDQDYAEGIFIVNAHVLWKAGRSGRALPALSPPPEG
                     QQSLGARVPVQLSGIHLQGVLYAAGDVRFAGHLKVYGGVAAQGAIMEAANGSGMLEVW
                     YNHDLREGFVQGLPVVFAAPGSWQTKL"
     gene            8539..10338
                     /locus_tag="PK063_08050"
     CDS             8539..10338
                     /locus_tag="PK063_08050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GspE/PulE family protein"
                     /protein_id="HMZ97040.1"
                     /translation="MIRASSPACLSNGLTLGKPRPTRSRPSGLYEPLVHQGFLRQEEL
                     ALAFSEALRRRLDVTTLLMDRYRIPKPAIGAVLAEFYECQFLAYDEQTIVEPELLKNL
                     SIDYLRMNHWVPLKRQAQGVEVLIDDPHNPDKLLDVRRAFPGQSVLYRVGLRADIERL
                     LSDACGREVGDPITDILGELVSEAQLEEQQNATIAAITENDSAIVRLANQIIAEAYRR
                     GASDIHIEPYADRKETAVRFRVDGTCFTYMKIPAAYRRAIVSRVKIMASLDIAERRKP
                     QDGKIRFKLTTGQEIELRVATLPTAGFNEDVVLRLLSANGPRRLEEFEFSVETRRVVE
                     QLAQKPHGIVLCAGPTGSGKTTTLHAILASINTDERKIWTAEDPIEITQDGLRQVQVH
                     PKIGLTFATTMRAFLRADPDVIMIGEMRDKETADIAIEASLTGHLVFSTIHTNSAVET
                     VVRLLDMGCDPFNFSDAMLGVLAMRLCKRICSHCREPYHPTRSEYDELVHAFGERDWA
                     SRQAAHDDTFTLFRGRGCEVCHHSGYRGRVPIHELMVVSDGMKALIQGRGRTGELLAL
                     AKSEGMQTLVQDGIGKVLQGLTTYQQVRAVAIK"
     gene            10676..10795
                     /locus_tag="PK063_08055"
                     /pseudo
     CDS             10676..10795
                     /locus_tag="PK063_08055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006751354.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
     gene            11160..11684
                     /locus_tag="PK063_08060"
     CDS             11160..11684
                     /locus_tag="PK063_08060"
                     /inference="COORDINATES: protein motif:HMM:NF019575.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HMZ97041.1"
                     /translation="MSYTTEYIASSQLITPRQLGFTLLEAMIAAGVLSVGLLGLAGLS
                     GMSLGKNVDANDMSRVTNIAMDMAERIQSNRQRVLDYNATATNVACPQSVSTQRMAWG
                     DCTQWSALVTNSGLQSAVGTVTASRLDPDPTANPVTMNRFLVTITVNWRTQKTDVSTS
                     RNKSAVFTTVIAPE"
     gene            11702..12808
                     /locus_tag="PK063_08065"
     CDS             11702..12808
                     /locus_tag="PK063_08065"
                     /inference="COORDINATES: protein motif:HMM:NF027400.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0043683 - type IV pilus assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilW family protein"
                     /protein_id="HMZ97042.1"
                     /translation="MMRRVTGNQQGFTLVELMAAVLITVVIVAATMTTVVTANRANVV
                     NSQVADTQQNVRLATDLLSRDIKLAGFNYNATDPATTAVGTCNATIGAVTKPVGLLPQ
                     DQSPTTADTGPDGVSMVLPVMNTTGWTLTAAAGGTANAPTFDSSISLSGTAITEMVAQ
                     GLAVNSTISIGGAISKTVKSVGATSIGFGAGNYVSGQFPIGTPVFLLQCVRYQVIVNT
                     PATCGSNAPCLVRDGVSLVDGVEDMQITYACDGCNQAAPNPLYPDGIIDDQDGSSSSG
                     FPTFTQGDFVSNGSWAITPRTPDKIRMAQVSLVVRPTKADDGLDEKGTKAVNTTGPVI
                     VGDHNPSTDTGYNAQTYQQQRRRVVIRTVQPRNL"
     gene            12877..13458
                     /locus_tag="PK063_08070"
     CDS             12877..13458
                     /locus_tag="PK063_08070"
                     /inference="COORDINATES: protein motif:HMM:NF025699.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilX N-terminal domain-containing pilus assembly
                     protein"
                     /protein_id="HMZ97043.1"
                     /translation="MTGQQGIALLTVMLMLLILSILGIASITVTSMENRMAGFFRTTE
                     AVVAAADSCEGLAANLIQQTLSPPGVLPTSFVAPTGPVPAANATILWQEIIGSSPLPS
                     PAPTGTLAENYADSAAMDPNFVMTNVAGFTVNGDIDRLYTHSKAGQGTGVTSTEFVYR
                     ITCTATNATTGSSSTVTSVYGCLDGDTCVKKVN"
     gene            13467..13802
                     /locus_tag="PK063_08075"
     CDS             13467..13802
                     /locus_tag="PK063_08075"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97044.1"
                     /translation="MTMNHLILLLILSLSMLVQAANPGPSVAGMEPEQAQEPILFSTV
                     GFQSGVIDEVQGSTIRIDGRTYVLKSAVVVVTHEGEPLAVERIIPTSLVKFHLKEGHI
                     DKMMVTLPQ"
     gene            13880..18301
                     /locus_tag="PK063_08080"
     CDS             13880..18301
                     /locus_tag="PK063_08080"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97045.1"
                     /translation="MNRRTLASLMIFAGSVSAGLCGSGDAAAVISNADYTAVPPFVSS
                     ATTPNIIILMDNSGSMSNRACESTSCGTLADGSTSTTTTWTNTTRYSGYFDSLRCYTY
                     NTTDKRFESATAKAYVYTDCSTTEWDGNFLNWATLRRFDAVKRAMSGGDCAVNRATDG
                     TCPTSGTPALKTVRAQATGVNDERADVNYSGGTGANTYVGRIPLADRGSNPGTISIGI
                     SASGTPAVPYFCVDNDTSFNSNCGDSYSVRKYELKVGYSTEPTGVIQQIGSKARFGLV
                     EFKSSSEGARMLVGAGSRQSIDWNGTGVETFNTNMAAMVDAVQESYPSTWTPLSESLY
                     ETARYVAQIQSTFVTGYVYPIAFSGGISNGVNFATTGAGSIGTDEITALVGTETCPAG
                     YITNACGRDPYFFGQNHTPPWASTSQVVNCCRTFVIIFTDGEPTQDVNVPTAIQDYAH
                     AHHGQHCNGSDSAAPPRPINGTCNTNAATPFSDLLAEHKTDYADSGSHYLDDVAYWAH
                     TSDLRPCSGTSDGTIAGLSVTGHCIPGTQNLTVYSFFAFGNINGRGILAQTARLGGFE
                     DANGDGIPQTSEWDKENNLTGASTPDGIPDAYFESSNVDDLQDKLLATIASILRRSAS
                     GSSVSVLATASTGEGALYQSYFYPSTIEPSTLSDVKWTGYTQALFIDTFGNTREDTNQ
                     DGRLDYKVDKIIKTRFDSLSNSVKVDKYVDSDGDGLPNDQNSDGVVTLADCNPCGKLL
                     SDILPIWEAGKQLALKDASTRTILTWVDSDHDGVVDSGEQIAFSTANETTLRPYLRAT
                     SSAEGTKIINFIRGCDATTCTDQATTRDRRLQVPSGSGTLKVWKLGDVIHSTPTVVAG
                     PRDRHDAIYGDQSYTAFLQKWYNRRQVAYVGGNDGMLHAFNAGYYHPGDDTSTSAPAS
                     TTEHGWFTTAPADNSSGAPLGDELWGFVPYELLPQLEFLSRADYQHAYYVDLPLKVAD
                     VRIFTADTDHPNGWGTILIGGFRMGGSCGACVAGTGAPPMTVNIGGTNYNFYSAYFAM
                     DVTNPDSPRLLWSFSSSDLGLSTSVPAVVRVNPAADAKASNTNAKWYMVVGSGPTGYD
                     ASVAQGAKVFAIDLATGPGSSNSLVTSYSIGSWDSYIGDMTAFDRDLDYRHDVVYFGR
                     VINDGALPWRGKIYRLTMGAGGATSKFGTVTSPSQWGISSGSARVPTEMLDTFASGAE
                     MGPVASAPSVTTDDAANVWVFVGSGRYYSKSDKTDISTQYFVGMKDSVLNAGCNQSSG
                     ITACMDSDLVDVSNATVCVVGVGDCGLATGTNQVTGVTGATTFTGLIGLVQSKDGWVT
                     KLVEPANPPTKPVPYGIGERAVSSPTVFGGVVFFPTFIPTNDICVSSGTSRLWALFYK
                     TGSAYQEPILGTTGAGANQTVNKFGSLGEGLAFGVVVHMGSGRDGGSPFGLLINMSQG
                     NFGDCATCTTGGGMFGSNISVPVAIDPRSRFFSWTNQ"
     gene            18544..19320
                     /locus_tag="PK063_08085"
     CDS             18544..19320
                     /locus_tag="PK063_08085"
                     /inference="COORDINATES: protein motif:HMM:NF017183.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative Ig domain-containing protein"
                     /protein_id="HMZ97046.1"
                     /translation="MADDPDGTEPTKRFQWIVNSAPVLGATGLELDPVHVKRGDQVSL
                     EVVAFDGELESAPYRTEPVSVVNTPPLVSHVTVEADAEHNSRVLAKVDAVDPDRDEIH
                     YNYRWWRNDKQVKEGEESILDTTGFGRKDVVVVEVIARDQDAAAAPVRSAPSALGNSP
                     PLIVSNPAALTNREQYEYVVQAKDVDGDTVSYVLETGPPGMTIDRATGQVSWKVIPGV
                     AGTHRVKIMAEDGQGGIAWQEFELSIPSTAQSQGSLPPQG"
     gene            19446..>20371
                     /locus_tag="PK063_08090"
     CDS             19446..>20371
                     /locus_tag="PK063_08090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HMZ97047.1"
                     /translation="MRKIKLREGTNTAVLFGHHDRHLKLIEEEFGVRCSARGEEVTVE
                     GAADAVKQAERVLNELASLTNEGYELRSDDVTHALTALRHNHDASLKELLFSASPIVT
                     RKRFIVPKTPTQKYYLDAIEKHDIVIGIGPAGTGKTYLAMAMAVSALMKKDVSRIILA
                     RPAVEAGEKLGYLPGDMYAKVNPYLRPLYDALFDMMDMERANRLIERGDIEIAPLAFM
                     RGRTLNDSFVILDEAQNATAEQMKMFLTRLGFHSKAVVTGDITQIDLPSDRVSGLIEV
                     RNILQDIAGIEFVYFDERDVVRHRLVQEIIKA"
     assembly_gap    20372..20471
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <20472..20662
                     /locus_tag="PK063_08095"
     CDS             <20472..20662
                     /locus_tag="PK063_08095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HMZ97048.1"
                     /translation="DERDVVRHRLVQEIIKAYDRHSAASAHPGSPRKGEQLGKGQHSD
                     AKAARSSVSPKGSWGQSH"
     gene            complement(20659..20991)
                     /locus_tag="PK063_08100"
     CDS             complement(20659..20991)
                     /locus_tag="PK063_08100"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97049.1"
                     /translation="MNQEHDQFMIDTPLMVAGLAYSLWQRYDDIPKKGRGWARSFPGG
                     KGQHISGFVAMAKGSIQATHPAVAYDFEAEERLTFTDGLEDTIGKLAERRQAQLPPRH
                     PHADHDRH"
     gene            21191..22105
                     /gene="ftsY"
                     /locus_tag="PK063_08105"
     CDS             21191..22105
                     /gene="ftsY"
                     /locus_tag="PK063_08105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HMZ97050.1"
                     /translation="MGWFQKLSEGLSKTRNAVTGQLDRLLGRAADPALLEELEVALIS
                     ADLGMPVVERVMENLRAQMRGGNFSAAEKVRELLRQSVLDILLPTQGASIDQLIAQGP
                     RPFVILAVGVNGVGKTTTVAKLTQRFRQQGNTALLVAGDTFRAAAIDQLQVWADRTQV
                     DIIRHRPGADPAAVAYDGITAAKARGSDVVLIDTAGRLHTKTNLMDELRKIKRIVAQE
                     CPGAPHEVLLVLDATVGQNAIAQARQFHEAVGVTGIALTKLDGTARGGIVVAIADTLK
                     IPVRLIGVGESVEDLQDFNAKAFVDALF"
     gene            22256..23041
                     /locus_tag="PK063_08110"
     CDS             22256..23041
                     /locus_tag="PK063_08110"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ97051.1"
                     /translation="MTTLLVIDDDRLHCDLLQVALSRHGYRVSTATSGREGVAIFRQL
                     RPVVTLLDLRMPEMDGLAVLKEIRTYDPRAGVIILGGGATEELENLARKLRVTDFFRK
                     GLSLDVLVGAVHRIAQQARREASATQDVTASEIDQPSEEQILVVDDDVMARDLLMRFL
                     SLRGYRVRGAKDGREALRMIEESAPDLLILDLVMPEMNGVELLKVLATREYAGRTIIL
                     SGHQNDPLLEDAWALGPQEVLDKPLDLERALMAIQLVMVCREC"
     gene            23411..25264
                     /locus_tag="PK063_08115"
     CDS             23411..25264
                     /locus_tag="PK063_08115"
                     /inference="COORDINATES: protein motif:HMM:NF013592.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family aminopeptidase"
                     /protein_id="HMZ97052.1"
                     /translation="MKQPATDRGYGAVALKFSYRGVVDDPPRDPRHLRFVTPSETSGH
                     IGPEGVYLSSESQWYPDVEGSLATYDVTIALPDGWTAVTQGAPQSDQGHWIVPTKSEA
                     LTVVANRFVVKSRTWTAKSGQSIRLATYLFPDEASLADEYLDASARYLDAYIPLLGPY
                     PFSQFAVVENFFSSGLGMPSFTLLGSGVIKRHYTQPYALGHEIVHSWIGNGVFNRIDR
                     GNWVEGLTTYLSNYYYHELMGDEAQAREQRRLMLMGYAVYVRPGEAYPVIQFAQKHDE
                     KDNAIGYQQAAMVFHALRQEIGEAVFWTALKQIPERYLGMAAEWRDLERVFQEAAGRD
                     LRWFFAQWVERAGVPDIEVTGSRVQQSTGTAGDMNRVEAIVHIAQHGTPYRLAIDLEF
                     VLDGGRTHRTRIHLTDAQQNAIIPLPERPLAVRLDPDLHVFRRVARNALAPMLNVYVT
                     DAHRTVVVAPASLQQPGPFTDIVQRIAAQEASKPEPSRTTVKQPEDKTKPTPEGSVLV
                     LGGPGENAAASDMLRYCGDHVHFTEKGFSVEGKSYEGPTMALLVSCRRDDQPGSVVTI
                     LYGVTPPALTRVARLLFFYGWQSYVVFHEGSVVARGDWEDRMTVEVRIETR"
     gene            25251..26378
                     /locus_tag="PK063_08120"
     CDS             25251..26378
                     /locus_tag="PK063_08120"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97053.1"
                     /translation="MKHAKQVMAGMLGLMLSLSMTNPAAAASKAAETATPTASTERHL
                     TNIKQLTFGRQNAEAYFSFSGDKLIFQSTNNWMKDTFAAAMHPADIPLGCYQMYVMDL
                     GSEKIRMVSTGSGTTTCGYFFPGDRRVLYSSTHLRGPNCPPKPKREGGAYRWALDDYD
                     LFSVRIDGLDPQRLTNTPGYDAEATVAPNGKTIIWTSMRDGDLDIYAMDLDGTHPRRL
                     TQEIGYDGGAFFSPDSKRIVYRAQHPSNQEELDQYKSLLAQNLVEPGRLEIFIMNADG
                     SNKQQVTSNGASNFSPYFHPDGHRVIFSSNVETRNEGGRPEFHLYLTNEDGSGLERVT
                     VGGKFNSFPMFSPDGKHLVWVSDRNAKEPGEFNVFLADWVP"
     gene            26375..27454
                     /locus_tag="PK063_08125"
     CDS             26375..27454
                     /locus_tag="PK063_08125"
                     /inference="COORDINATES: protein motif:HMM:NF013718.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HMZ97054.1"
                     /translation="MSESGDGQAAPVSTQPAPPPDRPPVLAVILSALVVLGSFAALFH
                     IDIPILRLLRSHNLSSLQSLGDLGEKLGNGGTLITISVLLLGAGYLLKRQAWIRTAVD
                     SLLAHGVVALVVNSLKHIIGRPRPRLTHSGGWHWWPSLQSGLDSFPSGHTSATVAVAT
                     VLARALPRLSWVPFALAAWVGASRIWRGSHFPGDVIGGMVLGFMVGSIFNGPLRWWGS
                     SCAHALVRIAPMVLLLTGWCWVVTHRILDPVTDTVLVASGVMLVLAGWLVQMLPRWRS
                     TSAGGIAAVVTSKGFLLSGVGLATGAPIVIVLTGLLCIARWNAAAQVLEAPAQPSWRR
                     DGLYTAAGLAGVMAIQFLKGLVPLE"
     gene            complement(27462..29243)
                     /locus_tag="PK063_08130"
     CDS             complement(27462..29243)
                     /locus_tag="PK063_08130"
                     /inference="COORDINATES: protein motif:HMM:NF014425.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 39 protein"
                     /protein_id="HMZ97055.1"
                     /translation="MNGEVPSLQTPAPIDRSIQPVTLVVLLALAAVLFFVGLGSLGLT
                     DRDEGRNAEAGREMFETGNYISPTFNYEPRFAKPVFVYWLMTASYHLFGVSEFAARFP
                     SALFGLGLILLQYLFLTRCRGPVIGLFGAAMLLLNLEIIGLSRMALTDSVLIFFTTLS
                     LYGFWLGLYGEGRERHCIWLFYIGMALATLTKGPIGFLIPLLAVGLYLWLTRSWPLFR
                     REGRLLPGLFLFVALALPWYLMMLNLHGQRYTTSAQGDTIGRFFGTMEGHGGTLLFYL
                     PVFILGFFPWSGLLPFAWYQAYRSWREAKQAGTFTPATGTDTPASSQALEWFAAAWVL
                     GGLVFFSLSSTRLPHYIGPLFPAAAILTASFWNRCVTDHAAPHLRAAIHMMTAVGYIL
                     ALAFASLPPLYAKFAVKLVDEFPLAGQVTLGPGPYTVASIFLVGMGLVAYFGLSETRK
                     PAAFWAAGGSLALVVLAVTQLTFPLVNHFVIEPPQRLADVAGLNLGPDDRLILYGQPR
                     PSLVFYAKRKAIVVPKGEEANIKPYLTQPGRTLILLPAAMRNRLPFETMEYPVMLERY
                     GYILLANQSMIHVPEEAEKPPIRIPGH"
     gene            complement(29255..29554)
                     /locus_tag="PK063_08135"
     CDS             complement(29255..29554)
                     /locus_tag="PK063_08135"
                     /inference="COORDINATES: protein motif:HMM:NF019214.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-A-disaccharide synthase N-terminal
                     domain-containing protein"
                     /protein_id="HMZ97056.1"
                     /translation="MTLDTIWLIIGFLGQGIFFMRWVVQWIASERHAESRVPTAFWYM
                     SMIGGLITLAYAIYRQDPVFIAGQSIGSIVYLRNLMLIHRPNSADSSTASPAIKS"
     gene            complement(29551..30327)
                     /locus_tag="PK063_08140"
     CDS             complement(29551..30327)
                     /locus_tag="PK063_08140"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HMZ97057.1"
                     /translation="MTVATRPWASVVIPIKDERDNLVPLTEQLVKVLDGREESRSAPF
                     ELIFIDDGSSDGSSDVLDSLAARYQTVKVFHFDRNYGQSAAFDAGFKRSTGELVMTID
                     GDLQNDPADIATLLPHINTFDLVCGWRKDRHDNLTRKISSRIANSVRSAVTGDRVHDT
                     GCSLKLFRRAVVEKMQLFEGMHRFFPALALMHGFTVTEVPVRHYPRTRGTSKYGVGNR
                     LFKGLYDLVAVRWMQHRCLRYHYRGATTSPSGSTSASVPL"
     gene            complement(30460..32151)
                     /locus_tag="PK063_08145"
     CDS             complement(30460..32151)
                     /locus_tag="PK063_08145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ97058.1"
                     /translation="MNRSPATTPPYPQYQLTEVLRDIFAHLGMLLRLERSILGIIASY
                     AVAIGFFLLCVPIAVQELVSTFSFAMEPRMIFTLALFVASSLTGVAAFRVLQARAVET
                     LQQRIYTRVAIAFTRLLPQLRDDTFATPQAHRFMEADLLTRALVAMVADLFNVAVVGT
                     IGMTMLILFHPYFVLYILVLILGFVGLLTIFGRGGFFITLEMSRLHYEIFGWIQNISH
                     NLPHLRAAGDSPYLLERTDTLTRIYARIRQRRSDTLTGRQYKAAALWQVVGHSGLLIT
                     AGLLVVDGQLTVGQFAAAEVLVGNLLLNMDTLARRMVAMFFTFVSCREMAAVFSLPTE
                     EDGAKEDVPATQFGESGIHLTCRNLSYRAQDGLPIFQNVSLEVAPGENVAILCGTNRA
                     KTALAKVLAGLHPPSTGFVRYNDMNLAEVRRDSISRVRGLILDSHPTLLDGTLEDNIT
                     LGRPAIEYQDLQWALRFVELDHDIDAMPQGLHTPVSSGQTHLSMSQILRLLVARAIVT
                     RPQILIFDGTLHNMLPATRDLLLRRLCAKDEPWSVIFVSNDPTFSTHVDRQVSIE"
     regulatory      complement(32173..32247)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            complement(32363..33193)
                     /locus_tag="PK063_08150"
     CDS             complement(32363..33193)
                     /locus_tag="PK063_08150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97059.1"
                     /translation="MTAALPLGYTGLPPQMPGAWAFWRLPVERNVVALQWDILATILL
                     TATIQSLFGVGVLLFGTPILLVLGYDFITALTILLPISLTINLLQVSKDYRYIQWPFY
                     RQILTLSIPCVVLCLLLVTTLKLNIGSIVGLFLIVAALKSVYGPFNRCIESLVRYERI
                     YFTVMGIVHGLTNLGGSLLTAMIHSKPYDKDQTRATTAVSYGTFALFQLITLSMSLGP
                     SAIATSTTALYMAVGVSMFLATELLLYSKMSTERYRTTFAAFLFLSGTALIFKSLFIR
                     "
     gene            complement(33218..33778)
                     /locus_tag="PK063_08155"
     CDS             complement(33218..33778)
                     /locus_tag="PK063_08155"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97060.1"
                     /translation="MLVCPILLFSGSLLWAEDLPLTRNVPIPDFQNRTESAKPYNFDA
                     PPEGMFRHIVLAEGFDEELGFQRTHEIVPVKPTERFSAGARPIFIVFELHQHYQSFQV
                     FGRCYPEEVAGVDGKVVVAEDAMYIALEDQTGYLKLFPTESGWKPGRYKVEIHAGEQI
                     NDMSLMGTMRFTITAASESEVPARSR"
     gene            33982..35427
                     /locus_tag="PK063_08160"
     CDS             33982..35427
                     /locus_tag="PK063_08160"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HMZ97061.1"
                     /translation="MTPVEDPDALPQPIGEYKPVDYWQAHINTLFYQLRGDQQRSFYQ
                     TFASADYRLAHALAADYFEQAVKRDKKAAAKSSASGDAASRPSLTVMEWGPGNGNLAA
                     CFLSHLQKLDKAGQIYPRVRYVLVDSHAPALERARTHPDLIPHLSKVESLCADVDNMS
                     TIADGTVDRIICNEMWNELATKLVVKKGGEYEEEHLRPNLNERKAAAIADWSAFVRAF
                     DAKDIEKLKQFPPFLDDLIWEREYHKVDWKDVPYRKTLTEFMKAIDEEVLVPVNLGAF
                     GSIKEAKRVLAPDAVGFSSFDAGTADMQVLNDPEKPCYGQFGGQYSFMVNLALIQAVA
                     KHLGITTTIIETQREFVGSRLGTNVMTLMDLLACHPTVGSKVQPWQLDQLTLKTIRTL
                     NEHYESPYQRKIEFPLRSEMPAEEREAAQGTLLSMKPNGIPDTIAYVTEEELSQAQGD
                     LEQLGYEREAWLMALGAPPSPVEYYHFAFRP"
     gene            35695..35979
                     /gene="tatA"
                     /locus_tag="PK063_08165"
     CDS             35695..35979
                     /gene="tatA"
                     /locus_tag="PK063_08165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase TatA/TatE family
                     subunit"
                     /protein_id="HMZ97062.1"
                     /translation="MFGSFGWMELLLILIIVLIIFGAGKIPQLGEGLGKAIKGFKKSV
                     HEADAIDVTANETEPAAAQPTAQIQQTGQSAPPPPAQQAGAAPPPRTTQG"
     gene            36073..36372
                     /locus_tag="PK063_08170"
     CDS             36073..36372
                     /locus_tag="PK063_08170"
                     /inference="COORDINATES: protein motif:HMM:TIGR01411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase TatA/TatE family
                     subunit"
                     /protein_id="HMZ97063.1"
                     /translation="MFGLGAGEILIILVIAFLLFGPKQLPEIGRQVGKAVKGFKETAD
                     DLKKTVEPELNMIQQEMKMVEQDFESSMKEAEEQINHATSGVEHGAEESGLPKQA"
     gene            36622..38292
                     /locus_tag="PK063_08175"
     CDS             36622..38292
                     /locus_tag="PK063_08175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate export family protein"
                     /protein_id="HMZ97064.1"
                     /translation="MKRIHGRTRWGRLAAIFGAAAISALQCLTLPAFAGFELPPGERI
                     TNLPAIPRNMPQKEAYELYDPVIGRNFDIKNLWMRADLRVRPEMRNNGCFGLQMNANG
                     TCNTFGTRGAAGAGGNKGNDFFVQQWMRLGIGYDLSPDVNFYVEIIDSATWGGNGTAT
                     NAGNGGDPLNHNCSATATGACRLGVRAAYMLVRNLADVQGLSMKVGRQYVVFGNHSLF
                     GHFDWANTGYSHDGVMFSYTGIKNWDIYAGWFRNSESDLNQAAAVGSGSGNIAGNASG
                     SDANRDADMIVFYNQLKMIPGMVIEPFYVYYKNNYGSSATAGVGNQAFGLGTAKHANQ
                     TRHMIGNRIEMRKGGFDFSNEVAWQFGQMGQAGACVGDQKCLHINAWATRNWIGYTFY
                     DTAWKTRLAFNLDYASGDSRNNTCTNGTNCKTANTFENFFPTNHIHMGYMDVQAWKNM
                     LSPSVNLQARPSARDHIELWYTNLNLANSKDCWYRASQGCYVFSNANNTKTHIGDEID
                     VAYTRMFADGKVALQAAYGTIFSGGYLTSTLNQQVNQHWAYMSLWMNF"
     gene            38372..38800
                     /locus_tag="PK063_08180"
     CDS             38372..38800
                     /locus_tag="PK063_08180"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97065.1"
                     /translation="MKKLMFVTLGVAALAIGSQPVTAQAQVADAIQAVNDAIVELTDA
                     PGLGKRTTVDVTKRWGSDRSVIDSATAKLQDGLSKAQSGGVGADAMRQLKLAVDYGKA
                     RMHKEARLSAQGALRHLCVANQDQGPGCDTVPKFGSYTAP"
     gene            39052..40914
                     /locus_tag="PK063_08185"
     CDS             39052..40914
                     /locus_tag="PK063_08185"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: protein motif:HMM:TIGR00614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HMZ97066.1"
                     /translation="MNDLSTQLHQQFGFSSFRPGQREVIDAVLSRRDAMAVMPTGQGK
                     SLCYQLPATILPGLTLVISPLIALMQDQVNSLKARHVAAAAFHSGLSEPERDKIVLNL
                     KLRRLQLLYLAPERMQHERFLRLLRSLWVSLLVVDEAHCISQWGHDFRPDYLNIGRLR
                     RELENPPCLALTATATARVQADLCERLSLHDPLRLVTGFRRPNLALSVRQCRSRQEKL
                     AQLERVVREYPTGTLLIYCATRRAVEEVAACLGRSNSSVGYYHAGLTDEERRSVHEEF
                     RVGTIRILAATNAFGMGIDKSDVRLVVHFDIPGSLEAYYQEVGRAGRDGHPAACLLLF
                     HERDVATQEYFIQQASKESGNAARVERMKTLLQDLLDYVAGTTCRQLAILDYFSDEVE
                     RALGPCGLCDRCKTPIQLPVDVVNDESSCAKAILTAVSWCGGRFGVTRIVEMLRGSRS
                     KGLLAHGAEDYPGYGIYQTWTKTALTRLVKSLIDTGHLQVEGSEYPTLDLTRRGQEVV
                     TGLRPVEVKTAVQSPASSAYQTPVNGPNNSMAASLTSSVDPQLFERLRQLRKELAEEE
                     GVAPFVIFHDKTLRTIAGHKPVTLSALLEIPGIGEVKVERYGRRVLGIVNEECR"
     gene            complement(40958..41578)
                     /gene="thrH"
                     /locus_tag="PK063_08190"
     CDS             complement(40958..41578)
                     /gene="thrH"
                     /locus_tag="PK063_08190"
                     /EC_number="3.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoserine
                     phosphatase/homoserine phosphotransferase ThrH"
                     /protein_id="HMZ97067.1"
                     /translation="MQNPVIVCLDLEGVLVPEIWVNFAIKTGIEELKITTREMPDYDA
                     LMTRRLKILDEHGYTLADIQSVIDAMGPMEGAAEFIAWLRERAQVIILSDTFYEFALP
                     LMRQLGFPTIFCNQLEIGPNGRIVSYKLRQPNQKKHAVAALKSLNFRVMAAGDAYNDT
                     AMLGEAHAGFFFRPPAHLPKEFPQFPVTTTYAELQEQFRKAGGLKA"
     gene            complement(41669..42466)
                     /locus_tag="PK063_08195"
     CDS             complement(41669..42466)
                     /locus_tag="PK063_08195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HMZ97068.1"
                     /translation="MTHQTAVEHFEISLQTPVGEVSTAIGVPTSFVPVTAILPLMRGL
                     GEEVQTLELAHVRDAGQTVSCQKGCAACCRMLVPISAPEAFALAKSIDRLAPPERDRL
                     LSKIDVTQQRLARAGILQQLSALAESSDPISDEAIEPLNRAYYALRMPCPFLDNEACS
                     IYDDRPAACRELAVTSPAADCQDMTNQTIRPVPVAVRISTALSLLWADLTATTPRLIP
                     LPLAIDWAKRHQAEQARQWAGTELFEKAIDKIGRYLGQERARRGSGG"
BASE COUNT         9093 a        11341 c        12915 g         9137 t
ORIGIN      
        1 tcgcttgggg tgcgaggggt cgtgggttca aatcccgccg ccccgaccat cggcacgatg
       61 tagtccatga ggtaccgttc taagagacgt tgatcattac gaccgaccat cttcacgtat
      121 ttgtgaagct tctcgccttc ttcccgcccc gcttgaacca gcgatttcag ttcttcccgt
      181 tcacgatgag ttccatgcat aaggagtgtc tgtggcgcgc gtacggattc ttgtaaccaa
      241 cgacgacgga attgcctctc ctggcattca cgccgttgcg gctgcgcttg gcaccctggg
      301 agaagtgtgg attgtcgcac cggaccgtga acgaacggcg gtgggacatg cggtcacctt
      361 gcacaagccg ctccgcatta ccaaaatggc gccgcgcgta tttatggtga atgggactcc
      421 cgtagactgt gtcaatctcg cgttggtgaa aattttgcct ggccctcccg cgttgatcct
      481 ctcgggaatc aatcgcggcg tcaatctcgg cgatgatgtc atgtattccg gcacggtgtc
      541 gggagcgctg gaagggacaa ttctcggcat accatcggta gcggtatcgc aggaaggcgg
      601 agagacgttc cggttcgagg ttggggcacg gtatgcgact cgagtggctg cacaagtgtt
      661 gcagcatgga ttgccggcgg aaaccatttt gaacgtgaat atccccgatg ttccctttcg
      721 ttccatcaag ggcgtgaagg tgacgtgttt gagtcgacgt cgattcaaca atcccatcgt
      781 ggagaaagtg gatcccagag ggcgcaaata ttattggatc gcagggacgc gtcaatcgtg
      841 gagccgtcaa caagacgccg accatgaagc cttagagcgc cgtatggtgt ccgtcacgcc
      901 gatccatctg gatacgacct atcacgcgat gctggaacac tttaaggcct gggagcaacc
      961 gctctctaag ctggcggcaa gccgtcgggt ggtcaaagcg cgttcttcga ggaggactcg
     1021 cgcgtgagcg ctctgatcga gtggttgatc gaagtattgg gccggttcgt cattgcgacc
     1081 atttcgacct tcggctacac cggcatcgtc ctgacgatgg caatcgaaag tgcctgtatt
     1141 cccctgccaa gtgagatcat tatgccgttc tccggctact tggtgttcac cggccaattt
     1201 tcgatggtgg gcgtcaccct ggccggtgcg atcggtaacg ttctgggatc cttagtagcg
     1261 tactatgtcg gcgtgtgggg ggggcgtccc tttgtcgagc ggtacggccg ctattttctc
     1321 gtctcctcac atgacatgga attggccgac cggtggtttg cgaaacatgg agaggcggcg
     1381 gtgttgatcg gccggctctt gccggtggtg cgaacgttca tctcgctccc ggcgggcatt
     1441 tcgcgcatgg acgtcaaaaa gtttgtcgtc tattcatttg tgggagcgct tccgttctgt
     1501 tatgcgctcg cctatgtggg attgaagatg ggagagcact ggaatgaatt acaccagtat
     1561 ttccatcatg cggatctggt gatcggtgtg ttgctggcca tgggcctcgg ttatttcctc
     1621 tggtcacatt ggcccaggcg ccgcacgtct atggagtaag gacgcaacat gttgcgcatc
     1681 tataatacat tgaccggaag taaggaaccg ttcgagtcga tggtcccagg caaggtccgc
     1741 atgtacgtgt gcggagtgac cgtctacgac tattgtcata tcggacatgc ccggagcgcg
     1801 ttggtctttg atgtgctgcg gcggtatttg gaatactccg gctttgccgt ggaatttgcc
     1861 aagaacttca ccgatgttga tgacaaaatc atcaagcgag cgaatgagca aggggtcagt
     1921 tgtgaccaga tcacggcgac ctacatcaag gcgtattacg acgatatgga gaggctcgga
     1981 gttcgacggg ccacccttga gcccagagcc accgagcaca ttgccgacat tgtcgccctc
     2041 gttgatacct tggtggccaa aggaatggct tatcgcgtca acggagacgt gtattttcaa
     2101 gtcgaccggt atccgggata tggccgtctt tccaagcgaa acactgacga tttgcaggcc
     2161 ggcgcgcgcg tggatgtaga cgagcgcaaa cgtcacccca tggattttgc cttgtggaaa
     2221 ggcagtaaac ccggtgaacc gtcatggaac agcccgtggg gtcctgggcg tccaggctgg
     2281 catattgaat gctcggcaat ggcgatgcgg caccttggtg aaacgttcga cattcatggc
     2341 ggcgggatgg atcttatttt tccacaccac gaaaacgaga ttgctcaatc ctgcggcgcg
     2401 accggaaaag aattcgcgcg ctactgggtg cataacggct ttgtgcagat caaccaagag
     2461 aagatgtcca agtcgttggg aaatttcttc accattcgcg agatttttga caagtctgaa
     2521 tggcctgacg cggtgaccgg cgagatgttg cgatactttc tcctgtccac gcactatcgc
     2581 ggccccttgg acttttctga tcaaagcctc gcggaagcca agaacgccct caatggactg
     2641 tatgatctct tcgagcgatt gaaagaaccg gctccttctc atggagcagc cgatcagcag
     2701 atgcgcgagg ccagcattcg aacacggcag gcgtttgcgg acgccatgga cgatgatgtg
     2761 aatacgccga atgctgtggc ggcattacag aagttgcgcg gagacgcgaa caaggccctt
     2821 gatgcaggac tgtctgctga gatgcggcat gctgtgcgga atgagtttcg ttcattgggt
     2881 gtggtgctgg ggctgtttca gcaggacagt tggcagttca aaagtcccgg gtcacgcgaa
     2941 acccagggtg cctccggtgt gtcagcgaaa tccctgtccg atgaggaagt cgctgacaaa
     3001 attgctgcgc ggttggcagc caaacaatcc aaaaactaca agttggctga cgaattaaga
     3061 gccgagttgg catcccacgg cattatcatc gaggaccggc ctgatggcac cagtcgatgg
     3121 aaaagataac acgccggacg taatttacgg cctgcatgcc gtgcgcgagg cactccgtgc
     3181 aggggctcgc cctattcagc gactgctggt gttggggacg gatcggcagt tcggggaaat
     3241 cgtgcggctt gccagagagc agcgcattcc tgtgtatgtc gagccacgcg ctgctttcga
     3301 tcgacttgtt ccctccggcc atcaccaggg cgtggttggg ttggtcgccg ccaagtctta
     3361 tagcgatccg gatgctattc ttgcctccgc gcaagccccc ggtcagactc cactgttggt
     3421 actgctcgac ggtgtcgaag atcctcacaa tctcggggcg attgtacgaa cggcagaagc
     3481 gtccggggtg cagggggttt ttattccgga acgccgtgca gtggggctga cgagtgtggt
     3541 ggccaaggcg tcagccggag cggtggatta tatgccggtc ggcagagttc ccaacctttc
     3601 gcggtggatt gagcgcctgc agcaggccgg gatctgggtg tatgcgctgg atgccgaagc
     3661 gccgaaggtg tatacgaaac tggacttccg ggggcctgtc gcgctggtat ttggtggaga
     3721 aggaaaggga gtacggccag gggttcgggg cgcctgcgat gatgctgcgc acattcctat
     3781 gtcggggaag gtcagctcgc tcaatgtctc ggcgtcagcg gccatcgttc tgtatgaggc
     3841 tgtgcgtcag cgtcgggaac gaggagagga tcgagtcgga cactgagacc gctggactat
     3901 ctcagcttga gcatttttcc ttgaatggcg gccttgagca gctgggccgt gttcgacacc
     3961 cggatcttct tcatcatgtt ggctcggtgt gcttcgacgg tcttcacgct gattttgagc
     4021 cgctgggcga tttccttgtt cttgaagccg gtccagatca attcaagaat ttcctgttcg
     4081 cgtgtggtga gggcttccgg acgtcgcttg cgagggggaa gaatcggctc ggatgatgcg
     4141 gctttggttc gacctttggt agtcctggca gctgtcggca tgtacgtctc gctccacttg
     4201 gaatatggca attctcagat tgaatcttcg actactcggc ccaaaacgtt gtcggattat
     4261 acgcagtgct cctggcgttt gtaaatgaaa agaggcgggt gcagaggggg gaccgcatgc
     4321 tcttattgac ctaggcgcgt atacgtgtac ttagatgcac gtgcgtggat ggaaaggagc
     4381 atgccgtggc gggaggcgtg atgatcccat atgtgatggt gttcttgttt ggtgcggtca
     4441 tcggtagttt cctgaacgtc tgtatctacc gattaccgcg cgaagagtct gtggcctggc
     4501 ccgcctcgca ttgccccgcc tgtcggcaac ctgtcgcggt atacgacaac attcctgttg
     4561 tcagctatct acttctgcgg gggcggtgcc gttcctgcca ggtgcccatt tccacccaat
     4621 atccgttggt ggaagctgtc aacacaatcg gatacgtgct gatcttttgg atgtttgact
     4681 tcacggccga ggcgttcgtg tattccgcct tactatcggc attgattgtg attacgggga
     4741 cggatctttc tcatacgatg attcctgatg ctgtgacctt gccgggaatt gctatcggcc
     4801 tcatctgtgc cgcggtgatt ctgccgattg gcctgattga ctcacttctt ggcgtcctcg
     4861 cgggtggagg tattctgtgg ttcctggctt gggtcagccc ctatgtcttc ggaaaagaag
     4921 gaatgggcgg cggagacatt aaactcatgg cgatggtcgg tgcgttcatt gggtggcagc
     4981 cggtattgtt ggccattatg atcggatcgt ttctaggctc cctcgtcggt gtcgcgctga
     5041 tcgccgccgg gctcaccaaa cgggatcaat atattccatt tggaccgttc ctcgcggcgg
     5101 ggtccctgct cgctcttctg tttcatcagc ctctcctcaa ttggtattgg tctctcatta
     5161 gcctgcccca gtaaatctct gcaaatcggc tgtcagagcc agtttgtagg cattgattat
     5221 tccgctgtct gtatcggaat ggttggcgca ctgtatctga ttnnnnnnnn nnnnnnnnnn
     5281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5341 nnnnnnnnnn nnnnnnnnnn nngcatctga attacgcatg gcccggcagc tggccatggc
     5401 gcggcacgaa cgtgtgcgag tcgtggtgaa tgcggcgcaa tccgagttgc ggactgaatg
     5461 tgtggactgt gagacgactg tgctccgtcg ctatgagttc gcacgcacag gcacagtggt
     5521 cgactcgatg agtaccaggc ccgagattct ttttcaatcc agcggccgtt ccgccacggc
     5581 cacgaccgtg gtcttgattg attccagacg cgtgacgcat caggtcacgg tgagcctcac
     5641 aggacgggtg tcactgtcat gaaacagcca gaggggaagc gggcaacaag gcaaggtctg
     5701 accacgagca cagcggggtt tacgctggtg gaaagcatgg tggccttggt cgtcctgtct
     5761 atcggagtca ttgggacgat cgcaatgtgt gagtgggcgc agcgtggcct tcaacgcggt
     5821 gcgatgacga cgacagcgtt ggctctcgca gaatcgtgcc tggaggcgaa gcgtagtctg
     5881 ccttgggatc aattgttggt cgatgacctc gatcagaacg ggacgctgga atctctcatg
     5941 cgcgacgacg gcctgctgga tgatgagacc aatggcgacg gtatcttcac cgggagtgtg
     6001 acgcggtcca acatcagact ggtctggacg gtggaactca atcgtggagg gcagcctgga
     6061 actgccagcc tggcgacgat tgaggcgcga gcgagtttca cgacgctcgg cggccagtcg
     6121 cgtgaagtgc gcgtgcgtac gatccgggca aatccgcgcg cggtcggtgc gatggcgctc
     6181 tcatgacacc cgccacactc tctgattcac aacagacgaa gccgatcagg gcgagatggt
     6241 gtctcaacac caggggggtc agccttatcg agcttctcat cgcgctggcg atcagcagcg
     6301 tggcgatagc ggcggcaatt caaacctctg ccgcctatgg ctctcgcttg agttcccagc
     6361 acgctaccat gacggccaat caagagctgc gactagggct ggatgtgttg tgtagcgaac
     6421 tgcgcttggc cggtggcgga ttattgagcg gagacactgt cttttcaaag atggaggtgg
     6481 acgaagtcga attttttgcc aatttgaacg gatcgtcaac catcctgacg cagatagtag
     6541 aagtcggccg gcaggacctg ccggtagaag acggcgccga ttggccgaaa ggcaagcagc
     6601 tgcttctgtg tactgcggcg cattgtgtct ggaatcgtct ggctgccgat ggccgaaagc
     6661 aaacgctgac gctcatgacg ccgactctcg aacagtatca gccgaaaacc gccatctttt
     6721 tgctgaaccg tgtgcggtac tacctaaagc gtgctgaagg aacacatcgg ctgatgcgag
     6781 aagtggatgg cgtggcaagt acgttgttga gcgagttgag cggaatgcag ctgcagtatt
     6841 tcaacaaaag cggaggtata gccaatgacg cgcgggatgt ggtgcgcgtt cgagtaacga
     6901 tacagggggc tcggcaagga atgaacctgt cgcgagatat cgcgatacga atgtgactaa
     6961 tgtaactaaa ggggaccggg gatatgaata ggagcggaga acgatcagca aagagaaggc
     7021 agggggatga acggggaatg gcattgttag cagtgctgat ggtggtgttt ctcctcaccc
     7081 tcttggggat gacatccatg cagttggcgg ggcaggaagt cgttggtgcc agtgcattgc
     7141 aggaagagcg gctcgcgcat cacgctgctg aggcggctgt ggatgtggtg atggggtggt
     7201 ttcatgatcc gacacttcgt ccacaggaaa tcgggacgac ctggtttagc aaacgactgg
     7261 tcaatgcaca gggagatcct tcatatgttg acgcgcaggg gcatggacag ttcatcggaa
     7321 cgagcacggc ccctgacgta gtgttcgatg cagccaacat ccagcacgac cgactcctga
     7381 atgatccgca gacaggctgg ttcaaatcgc tcaagggtct cgcgaaaatt ctcaaattac
     7441 gagtctatgg agcgacgaga ccgggtttgc tctgcacggt cgaagtgacg gctggggccg
     7501 gccctgcctc ccgtgtgaca aaaacgttga gcttggaatt cggggcctac gccgttcctg
     7561 ctcttcatgc gcccctgcaa agtggcaccc ttggcagcga ggcggtgcaa tcccgttccg
     7621 gttcggtttt tacgcattgg ggtgaaatgg tggtgcgcgg acgagcctat ctcccccgcc
     7681 cggaagacgt tccagtcaag agtgcactgg ctcctgtgag tggacaagtc tatgacgaaa
     7741 tgagtcatcg ggaagatcgc tggttgacga tccggctggg gggcgatgct ttttttgccc
     7801 agcttccggc cgaagcttgg tccggcgtgc cattgaatgt gcatgcgcat caagagccgg
     7861 tccccggcat taaggtggat cagtgggagt atgcgacctt gaagcgaatg gcgatgcagt
     7921 ttggccaggt gtacgggatc gatcgagagg gattattgta tgcgggcggt gtcattcagg
     7981 ccggcatggg gcgtcctgca tccgaggtgt ttgcttcaaa gggaccgggc gatcatcgtg
     8041 gactcgtgtt tgtagacacc cttgatggga tgccgcctcg cttcgataac ttgggcacga
     8101 tcgtgctcga tcaggactat gccgagggta tctttattgt gaatgcgcat gtgctgtgga
     8161 aggctggccg ttcggggagg gccttgccgg cactaagccc gccgcccgag gggcagcagt
     8221 cgcttggggc acgggttccg gtgcagctct cgggcattca tcttcaaggc gtgttgtatg
     8281 ccgcaggtga tgtgcgattt gccgggcatc tcaaagtcta tggtggggtg gcggcgcaag
     8341 gagcgattat ggaagcggcc aatgggtctg gaatgctgga ggtttggtac aaccacgatc
     8401 ttcgtgaagg gtttgtccag gggttgccgg tggtatttgc cgcacccggt agttggcaga
     8461 ctaaactgtg agaggatgag cgccctctcg caatcagatc atcaccccat gtttaaatca
     8521 gttgaaaagg atagggccat gattcgtgca agttcccctg cgtgtttgtc aaacggactc
     8581 acattaggaa aaccacggcc aactcgtagc cgtccatccg gactatatga gccactcgtt
     8641 caccagggat ttctccgaca ggaggaactg gcgctggcct tctcggaagc gttgagaaga
     8701 aggctggatg tgaccacgct actcatggac cggtacagaa ttcccaaacc ggcgattggc
     8761 gcagtccttg cggaattcta tgaatgccag tttctcgcct atgatgagca gactatcgtg
     8821 gagccggagt tattgaaaaa cctgagcatt gactatctga gaatgaatca ttgggttccc
     8881 ctcaaacgtc aagcacaggg ggtggaggtt ttgatcgatg atccacacaa ccctgacaag
     8941 cttctcgatg tgcggcgcgc ctttccaggg cagtctgtcc tataccgcgt tggtctgcgg
     9001 gccgatatcg agcgcctgtt gagtgatgcg tgcgggcgtg aggtcgggga tcccatcacg
     9061 gatattcttg gcgagttggt gagcgaagcg cagttagaag aacagcaaaa tgccacgata
     9121 gcagcgatca ccgaaaatga ttcggccatc gttcgtctcg ccaatcagat catcgccgag
     9181 gcctatcggc gaggtgcatc ggatattcat atcgagccct atgccgaccg caaagaaacg
     9241 gccgtgcgtt tccgggtcga tgggacctgc tttacctaca tgaagattcc tgccgcgtat
     9301 cgtcgggcga ttgtatctcg cgtgaagatc atggccagcc tggatattgc cgaacggcgg
     9361 aagcctcagg acggaaaaat ccgcttcaaa ttgacgaccg gccaggagat tgaattgcgt
     9421 gtcgcgaccc ttcccactgc aggatttaat gaagatgtcg tgcttcgcct gctgagcgct
     9481 aatggcccca ggcgactcga agagtttgag ttcagcgttg agacgcgccg cgtagtcgag
     9541 cagttggcgc aaaaaccaca tggcatcgtg ttgtgcgccg gcccgaccgg atccggaaaa
     9601 acgacgacat tgcacgccat tctggcatct atcaatacgg acgaacgaaa gatctggacg
     9661 gccgaagacc cgatagagat tacgcaagac ggcctgcgac aggtgcaggt gcatccgaag
     9721 atcggcctga cgtttgccac caccatgagg gcctttttgc gagccgatcc cgatgtcatt
     9781 atgatcggtg aaatgcgcga caaggaaacg gcggatattg ccattgaagc ctcgttaacg
     9841 ggtcatctgg tgttcagcac catccatacg aatagcgccg tagaaacagt cgtgcggttg
     9901 ctcgatatgg gctgtgatcc attcaacttt tctgatgcca tgctaggtgt ccttgcgatg
     9961 cggttgtgta agcgaatttg ttcgcactgt cgggagccct accatccgac tcgcagcgaa
    10021 tatgatgaat tggtgcacgc gttcggagag agggactggg catcccggca agccgcgcat
    10081 gatgacacgt tcacgttgtt tcgcggacga gggtgcgagg tgtgccatca cagcgggtac
    10141 cgcgggcgag tgccaattca tgagttaatg gtagtttccg acggcatgaa agcgctcatt
    10201 caaggacggg gtcgcaccgg agaattgctg gcactcgcaa aaagtgaagg tatgcagaca
    10261 ctcgttcagg atggcatcgg gaaggtcctc caaggcctca cgacatatca gcaggtgcgc
    10321 gcagtggcta ttaagtagcg ttgttgtccg tagttgttga tgaatctgcc tcaaagcagg
    10381 tccactcgca gaaagatggt gtcagttcgt tcggcctgcg atcaggaatg taattccctt
    10441 ttcttccaag tttgtagtcc cttgtcccgg gctcatcacg cctcccttca cctgctgttg
    10501 accctccccg atgggcaaag atcgccatcg accagacgaa aattgtcatc tcggtgatca
    10561 gaaaacgctc cgaagtgtac gggcgcggat atgaatgcgc tcgagatatc aattggttag
    10621 gtacatagtc ttctgaaaat gcatcggcat ggcacttgct catctgcctg ttgctatgtg
    10681 tgtctttccc tatcaccaac ggtcctctgt tgtccgttgt cagagaggtt tcacgctcat
    10741 cgaagtgatg atcgccgtag cgattgttgg catcttggcc atggtcgccg tccctaatta
    10801 tctgcaatgg aatgcccgct atcagctgaa gcagggcacg accgaattgg caggcagtct
    10861 gacgctggcc cgtatggccg cgatgaatcg gaatctggcc gtcacggtga ccctggcgtt
    10921 ggcttccggg agagtgaccg tcgatttcgg cggggcactc gctcccatcg tcctgcccca
    10981 agcgatagtt ggatttaccg ggggccccac agtgcagttc acccgacaag gattaagcgg
    11041 atcaaccgca aacgtgccgc tgaccctggt ttctcaacaa gggaccgtct actcgctggt
    11101 cgtcaccccg tcaggcaaag tgaactggtg cgcccacgcc acgtgcccat agaggctgca
    11161 tgagctacac gactgaatac atagcgtcct cacaattgat cacgccgcgt cagctaggat
    11221 ttaccttgtt ggaggcgatg atcgcagcgg gcgtgctttc tgtcggtcta ctaggacttg
    11281 cgggattgtc gggaatgtct ctggggaaaa atgttgatgc caacgacatg tcgcgtgtca
    11341 cgaatattgc catggatatg gctgagcgta ttcagagtaa ccgtcagcgg gtgttggatt
    11401 ataacgccac tgcgacgaac gtggcctgcc cacagagtgt gagcacgcaa cgcatggcgt
    11461 ggggcgactg tacccaatgg tcagcgttgg tcacgaactc cggtctccag tcggctgttg
    11521 gtaccgtgac agccagccgt ctcgatcccg atcccacggc aaatcctgtg acgatgaatc
    11581 gctttttggt caccatcacg gtgaactggc gtacccaaaa gaccgatgtg agcacctcgc
    11641 gcaacaagag cgcggtgttt acgacggtga ttgcaccgga atagacgcga tggagagcct
    11701 catgatgcgt cgagtgacag gcaaccaaca gggcttcacg ctcgtggaat tgatggccgc
    11761 ggtgttgatc accgtggtga tcgtcgcggc gaccatgacg acggtggtga cggcgaaccg
    11821 agccaatgtt gtgaatagtc aagtggctga cacccaacag aatgtccggt tggccactga
    11881 tttgctgagc cgagatatca aactcgcagg gtttaattac aacgccaccg acccggcgac
    11941 caccgcggtc ggaacctgca atgcgaccat tggtgcggtg accaagcctg ttggacttct
    12001 tccgcaggac caatcaccca ctacggcgga tactgggccc gatggcgtct cgatggtgtt
    12061 gccagtcatg aacaccacgg ggtggacttt aacggcggcg gcaggtggca cagccaatgc
    12121 cccgaccttc gatagttcca tcagcctctc aggaacggcg attaccgaaa tggtcgctca
    12181 aggcctcgcg gtcaattcaa ccatttcaat cggtggagcg atctcgaaga ccgtgaaatc
    12241 cgtcggcgca acgtcgattg ggttcggcgc ggggaattat gtgagtggac aatttcccat
    12301 cgggacgccg gtgttcttgc tgcagtgtgt ccggtaccag gtcatcgtga atacgccggc
    12361 cacctgtggg agcaatgcac catgcttggt cagggatggt gtgtcgctcg ttgatggtgt
    12421 tgaagacatg cagatcacct acgcttgtga cggatgcaac caggctgcgc caaatcccct
    12481 gtatccggac ggtatcatcg acgaccaaga tggctcgtcc tccagtgggt ttccaacctt
    12541 cacgcaggga gattttgtgt cgaacggttc atgggcgatt acaccgagga cgccggacaa
    12601 gatcagaatg gcgcaagtga gccttgtggt gagacccaca aaggcggatg acgggttgga
    12661 tgaaaaagga accaaagccg tcaatacgac tgggccggtc atcgtcggtg atcacaaccc
    12721 atccacggac accggttata acgcgcagac ctatcagcag caacgaagac gggtggtgat
    12781 tcgcacagtg caaccacgaa acctgtaatg agagacgccg cgatgaatgt gcgacacgcg
    12841 tcaaaagcta gacaactgat gcaaggcgag agtcgagtga ctggacagca aggcatcgcg
    12901 ctcctcaccg tcatgctgat gttgctgatt ctgtcgatcc tcggtatcgc ttccatcacg
    12961 gtgaccagca tggagaaccg aatggcgggg tttttccgca caaccgaagc cgtcgtcgcg
    13021 gcggcagatt cgtgcgaagg ccttgctgcc aacctcattc agcagacctt atcaccccct
    13081 ggcgtgctgc cgacctcgtt tgtcgcaccg acagggcctg ttccggcagc caatgcgacg
    13141 attctctggc aggagatcat tggttcctcg ccgcttccat caccggcgcc caccggaacg
    13201 ttggctgaaa actatgcaga ttccgcggca atggacccga attttgtcat gacgaatgtg
    13261 gcgggattta ccgtgaatgg tgacatcgac cggctctata cccattccaa ggccggtcag
    13321 gggactggag tgacctcaac agaatttgtc taccgaatca cctgtacggc gacgaatgcc
    13381 accactgggt caagcagcac agtgacatcg gtctatggat gtttggacgg cgatacatgc
    13441 gtgaaaaagg tcaattgaga gagggtatga cgatgaatca cctcatcctt cttctaatcc
    13501 tgagcctttc tatgttggtg caggcggcca acccaggacc atccgtcgcg gggatggaac
    13561 cggaacaagc tcaagaacca atcctgtttt cgacggtcgg ctttcagtcc ggtgtcatcg
    13621 atgaggtgca gggatcgacg atccgcattg atgggcggac gtatgtattg aaatctgccg
    13681 tagtggtcgt gacacacgag ggagagccgt tggctgtgga gcggatcatt ccgacgtcgc
    13741 tcgtcaaatt ccatctgaag gaaggccaca tcgacaagat gatggtcacg ttgccgcaat
    13801 agcgcatgaa aggtcttgtc tcaactcgta gccgacgcac cacggctgtt gtcctgcttg
    13861 agataaggag ggagaacgca tgaatcgacg aactcttgcc tcgctgatga tcttcgccgg
    13921 gagcgtgagt gccggtctgt gtgggtccgg cgatgcggca gccgtcatct ccaatgcgga
    13981 ttacaccgca gtaccgccct ttgtgtcgag cgcgacgacc ccgaatatca tcatcttgat
    14041 ggacaattcc ggcagcatga gcaatcgagc gtgcgaatcc acctcttgtg gcacattggc
    14101 ggatggcagt acgtcgacga cgacaacgtg gactaatacc acgcggtatt cgggctactt
    14161 tgattctctc cgctgctata cctacaacac gactgacaag agatttgaaa gcgctaccgc
    14221 aaaagcatat gtgtacacgg attgttcgac gacggaatgg gatggcaatt ttttgaattg
    14281 ggcgacactg cgccggttcg atgcggtgaa acgggcgatg tccggaggag actgtgccgt
    14341 aaatagagcg acggatggca cctgcccgac cagtggaacg cctgcgttga aaactgtgcg
    14401 tgcccaggcc accggggtca acgatgaacg agccgacgtg aattacagcg gtggcactgg
    14461 agccaacacg tatgtggggc gcattccgtt agccgatcgg ggtagcaatc cagggacgat
    14521 ctcgattggt atctccgcga gcggaactcc ggctgtgccg tatttttgtg tggacaatga
    14581 taccagtttc aacagtaatt gcggagactc atacagcgtt cgtaagtatg aattgaaggt
    14641 tgggtattcg actgaaccca cgggggtcat tcagcagatc gggagcaagg ctcgcttcgg
    14701 cctcgtcgaa ttcaagtcca gtagtgaagg tgcgcgcatg ttagtcggcg cgggttctcg
    14761 tcaatccatt gactggaatg gtacaggagt agagacgttc aatacgaaca tggcggctat
    14821 ggtggacgcg gtgcaggagt cgtatccctc cacctggacg ccactgagcg aatcactcta
    14881 tgagacggca cggtatgttg cgcagattca atcaacgttt gtcacaggct acgtgtatcc
    14941 gatcgcgttt tcaggaggca tttcaaacgg agtcaatttt gccaccaccg gtgctggttc
    15001 cataggcacg gacgaaatca cggcattggt tggtaccgaa acctgcccgg ctggatacat
    15061 cacgaacgcc tgtggccgcg acccctactt ttttggccaa aaccacacgc cgccttgggc
    15121 gtcgacttct caggtcgtca attgctgccg gacgttcgtc attattttta cagacggtga
    15181 gccgacgcaa gacgtgaatg taccgacggc gattcaggac tatgcccatg cccatcatgg
    15241 gcagcattgt aacggcagcg atagcgctgc tcctcctcgg cctatcaacg gcacttgtaa
    15301 tactaatgcg gcgaccccct tcagtgatct gttggctgaa cacaagactg attacgccga
    15361 cagcggaagc cattacttag acgatgtggc ctattgggcg cacaccagtg atttgcgccc
    15421 ttgcagtgga acgagcgacg gcacgatcgc agggttatct gtcactgggc attgcatacc
    15481 cggcacgcag aatctcaccg tgtattcatt ttttgcattt ggcaatatca atggtcgagg
    15541 aattctcgcc caaaccgccc gcttgggggg atttgaagat gcgaacggag atgggatccc
    15601 ccagacttcc gaatgggaca aagagaacaa tttgaccgga gcgtcaacac ccgacggcat
    15661 tccggatgcg tatttcgaat cctcgaacgt ggacgatctc caagacaagt tgttggccac
    15721 cattgcaagt attctccggc ggagcgcgtc gggttcttcg gtgtcggtat tggccactgc
    15781 ttcaactgga gaaggcgcgc tgtatcaatc ctatttctat cccagcacga tcgagccctc
    15841 gacgttgagt gacgtgaaat ggacgggata tacccaggca ttgtttatcg atacgttcgg
    15901 caacacgcga gaggacacga accaggacgg tcgccttgac tacaaggtcg acaagatcat
    15961 caagacccgc ttcgactcac tctctaactc ggtgaaggtc gataaatatg tcgattcgga
    16021 tggcgatgga ttgccgaacg atcagaacag cgacggcgtc gtcacgctgg cggattgcaa
    16081 tccctgcggc aaactattga gcgacatatt gccgatctgg gaagccggga agcaattggc
    16141 gttaaaagat gcatccaccc gtaccattct cacttgggtc gattccgacc atgacggagt
    16201 ggtggattcc ggtgagcaga tcgcgttctc caccgcgaac gaaacaacgc ttcgtccata
    16261 cctgcgtgcc acgtccagtg cagagggaac caaaattatt aactttatcc gtggatgtga
    16321 tgccacaaca tgcactgatc aagcgacgac cagagatcgc cgtctccagg ttccttcggg
    16381 aagcggaacg ttaaaagtgt ggaagctggg agacgtcatc cactcgacgc cgactgtcgt
    16441 ggcgggtcct cgagaccgtc acgatgcgat ctacggagac cagagttaca ccgcgttcct
    16501 gcagaagtgg tacaaccgca gacaggttgc ctacgtgggc ggaaatgacg gcatgctgca
    16561 tgcgttcaac gccggttact accatcccgg tgacgatacg agcacgtctg cgcccgccag
    16621 cacaaccgaa catggttggt ttacgacggc tcccgccgac aattccagcg gagctccgct
    16681 tggggatgag ttatggggat ttgtccccta tgaactcctc cctcagctcg agtttctgag
    16741 ccgtgccgat tatcaacatg catactatgt tgacttgcct ctcaaggtcg ccgatgtgcg
    16801 gatcttcacc gcggataccg atcatcccaa tggatggggc actattctga tcggcggctt
    16861 cagaatggga ggcagttgcg gtgcctgtgt ggcgggaact ggtgcaccgc cgatgacggt
    16921 gaacattggc ggaaccaact acaatttcta tagcgcttat ttcgcgatgg atgtcaccaa
    16981 tcccgatagc ccgagattgc tgtggtcatt cagcagctcg gatttgggat tgtcgaccag
    17041 cgtcccggcg gtcgtgcgtg tgaatccggc cgccgatgcc aaagccagca atacgaacgc
    17101 gaagtggtac atggtcgtcg ggtccggccc gaccgggtac gacgccagcg tggcgcaggg
    17161 cgcgaaagtg tttgccatcg atctcgcgac aggaccggga agcagtaaca gtttggtgac
    17221 ctcatattcc atcgggtcat gggattcgta catcggagat atgacggcgt tcgatcgtga
    17281 cctcgactat cgtcacgatg tcgtctactt cggccgcgtc atcaatgatg gggctctccc
    17341 ttggagggga aagatctatc ggctgaccat gggggcaggc ggggcaacct caaaattcgg
    17401 tacggtcacg agcccttcgc aatgggggat ttcctccggt agcgcgcgcg tcccgacgga
    17461 aatgttggat acctttgcgt ccggagcgga gatgggcccg gttgcaagcg ccccttccgt
    17521 cacgacagat gacgcggcta atgtctgggt gtttgtgggg agcggccgtt attacagcaa
    17581 gtctgataag accgacatct ccacccagta cttcgtaggc atgaaggatt cagtactcaa
    17641 tgctgggtgc aatcaatcaa gcggtatcac cgcctgcatg gacagcgatc tcgtggatgt
    17701 gtccaatgcc actgtgtgtg tggtgggcgt tggcgattgc ggactggcga ccggtacaaa
    17761 tcaggtgacc ggtgtgaccg gcgcgaccac gttcacagga ctgattgggt tggtccaaag
    17821 caaggatgga tgggtgacca agctcgtcga gcctgccaat ccacccacga agccggttcc
    17881 gtatggtatc ggagaacgtg ccgtcagtag cccgacggtg tttggagggg tcgtattttt
    17941 ccccaccttt attccgacca atgatatctg cgtgtcgtct ggcaccagcc ggctctgggc
    18001 cctgttctac aaaacaggaa gcgcctatca ggagccgatt ttgggtacga cgggagcagg
    18061 cgcgaatcag acggtcaaca aatttggatc actaggcgaa gggttagcat tcggtgtcgt
    18121 ggtgcatatg ggctccggca gagacggcgg aagcccgttc gggttgctga tcaacatgag
    18181 ccagggaaat ttcggagact gtgcgacctg cacgacaggt ggaggcatgt ttggatcgaa
    18241 catcagcgtt cctgtcgcga ttgacccgcg gagtagattt ttctcatgga ccaatcaatg
    18301 aagactggtg tctggagcct ggttgaaagg tgtggggaaa gactctgtcc ccacaccgtc
    18361 atttcatccg ctcgatggct gttggctgct tcggtcgtcg ccgttgtagg ggggtgctcg
    18421 tcctctccgc aagacggatc agtggtcagt ggtgcgacaa agaataacca cgctcccgtt
    18481 gttcgccttg tgacgattgt gccaaaccca ctcatactcg caggacctat cacggcacat
    18541 gtgatggcag atgaccctga tggtaccgag cctaccaagc gatttcagtg gatcgtcaac
    18601 agtgctcctg ttttgggggc aaccggcctt gaactggatc cggtccatgt gaagcgagga
    18661 gaccaggttt cgctggaggt tgtagccttc gatggtgagc tggaaagcgc tccctatcgc
    18721 acggagccgg tttctgtggt gaacactccc cctctcgtgt cacatgtcac cgttgaggca
    18781 gatgctgaac ataacagccg ggttcttgcc aaggtcgatg ccgtcgatcc tgatcgagat
    18841 gaaatccact acaactaccg gtggtggcgc aacgacaaac aggtcaaaga aggtgaggaa
    18901 agcatcctcg acaccacagg atttgggcga aaagatgtgg tggtcgttga agtgattgcg
    18961 cgggatcagg atgcagcagc tgcgccggtc cgctcggccc cgagcgcgtt ggggaattca
    19021 ccgccgttga ttgtttccaa cccggcggcg ctcacgaatc gagaacaata cgagtatgtg
    19081 gtccaggcca aggatgtgga tggcgatacg gtgagctatg tcttggagac aggccccccg
    19141 ggaatgacca ttgacagggc aacaggccag gtcagctgga aagtcattcc gggagtggcg
    19201 ggaactcatc gagtgaagat catggcggaa gacgggcagg gcggaattgc ctggcaggag
    19261 tttgaactct cgattccctc cacggcgcaa tcgcagggct cgttgccgcc tcaagggtag
    19321 ccggcttctc gagacctcag ttccgctaat ttttccccac cccccctgtt ccgaccttgt
    19381 tcctcccttt cgcggtttgt tagaatctag acatcagctt ggcgaaagga gtcttcgaca
    19441 caggcgtgcg caagatcaaa ctacgtgaag gcacgaacac tgcggtccta tttggacacc
    19501 acgatcgcca cctcaaattg attgaggaag agttcggggt gcggtgttcc gcacggggcg
    19561 aagaagtcac ggtagagggt gctgccgatg ccgtgaagca ggccgagcga gtactcaatg
    19621 aactcgcatc gctcaccaac gaaggctacg aactcaggtc ggatgacgtc actcacgcat
    19681 tgaccgccct ccgccacaat cacgacgcct ccctcaagga actgctcttc agcgcgtccc
    19741 ccattgtcac ccggaagcgc ttcatcgttc ctaagacccc gacacagaaa tactacctcg
    19801 acgcgatcga aaagcacgac atcgtcatcg ggattggtcc tgccggcaca ggtaagacct
    19861 atttggctat ggctatggcg gtgagcgcgc tgatgaagaa ggatgtcagc cgcattatcc
    19921 tcgcgcggcc ggcagtcgaa gcgggcgaaa aactcggtta tttgccgggg gacatgtacg
    19981 cgaaggtgaa tccgtatctt cgtcctctgt acgatgcgct gttcgatatg atggacatgg
    20041 aacgagccaa tcgtctcatt gagcggggag atattgaaat cgctcctctc gcgttcatgc
    20101 gaggccgcac cctcaacgac tcgttcgtga ttctcgacga agcccagaac gcgacggctg
    20161 agcaaatgaa aatgttcctc acccggttag gcttccattc caaagccgtc gtaacaggcg
    20221 atatcacaca gatcgatttg ccatccgacc gcgtctcggg gctgattgaa gtgcggaaca
    20281 tccttcagga tattgcgggg attgagtttg tgtatttcga tgaacgggat gtcgtgcggc
    20341 atcggctcgt ccaagagatc atcaaagcgt annnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20461 nnnnnnnnnn ntcgatgaac gggatgtcgt gcggcatcgg ctcgtccaag agatcatcaa
    20521 agcgtacgat cggcattcgg ctgcgtcggc acatccgggc tcgccgagaa aaggcgaaca
    20581 gctgggaaaa gggcagcatt ctgatgctaa agctgctcgg tcatcagttt ctcccaaggg
    20641 ctcctggggc caatcacact aatgccggtc gtggtcggca tgcggatgac gaggaggaag
    20701 ctgcgcctgg cgtctttcag caagcttgcc aatcgtatcc tccagtccat cggtgaaagt
    20761 aaggcgctcc tcagcctcga aatcgtaggc gacggccgga tgcgtcgctt gaatcgaacc
    20821 tttcgccatc gcgacaaaac cactgatgtg ctggcctttg ccaccaggga aggacctggc
    20881 ccaccctctg cccttcttgg ggatgtcgtc atatcgttgc cacaagctat acgccagtcc
    20941 cgcgaccatc agcggggtat cgatcatgaa ttggtcgtgc tcctgattca tggtgttcta
    21001 catttgtgtg gctatgatca cgaacggagc gacgccgagg cgaggcgaat ggccagacgc
    21061 gagcgggccg ttctgcgtga cattggctcc attcccaagc tattggtatc ccgcgaatca
    21121 gatccagtat gatgctggac gtcagtacat gatcggggac gtgaacgtcg acacagggat
    21181 gaggtgagcg gtgggttggt ttcagaaact gagcgagggc ctctcaaaaa cacgtaatgc
    21241 ggtgaccggg caactggatc gccttctggg acgcgcggct gatccggccc tgttagagga
    21301 gctggaggtc gccctcatca gcgcggattt ggggatgccg gtcgtagaac gtgtcatgga
    21361 gaacctgcgt gctcagatgc gcggagggaa tttctcggct gccgagaagg tgcgggagct
    21421 gctgcgccaa tccgtcttgg acatcctctt gccgacgcaa ggggcgtcga tcgaccaact
    21481 catcgcgcaa gggccgcgtc ccttcgtcat tctcgccgtg ggagtgaacg gtgtcggcaa
    21541 gaccaccacc gtcgccaaat tgacccaacg gtttcggcaa caaggaaaca ccgcactgct
    21601 ggtcgctggt gatacattcc gggcggcggc gatcgatcaa ttgcaagtgt gggcggaccg
    21661 tacccaggtc gacatcatcc ggcatcgacc gggtgccgac cccgcagccg tggcctacga
    21721 cgggattacg gccgccaaag cacgaggatc cgatgtggtc ctcatcgaca cggcaggccg
    21781 actccacacc aaaaccaact tgatggacga actgcgcaaa atcaaacgga ttgtggcgca
    21841 ggagtgtccg ggtgcacccc atgaggtgtt gctggtcttg gatgcgacgg tgggacaaaa
    21901 tgccattgcg caagcccgac agtttcacga agcggtcggg gtgaccggca ttgcgttgac
    21961 caagctcgat ggcacagccc gcggggggat cgtggtggca attgcggata ccctcaaaat
    22021 cccggtccga ttgatcggcg tgggggaatc cgtcgaggac cttcaggatt tcaacgccaa
    22081 ggcatttgtc gacgcattgt tttgaccaat agctgaaccg gccccgttct gctgcccttc
    22141 ctacagtttc cgtcaatttc ttctcatcct acgaagctca tgctaggctg tttcgtgaga
    22201 cttcggccgg aaaaggctga gggtaaggcc tgtcgcatat gggtgagaat cgactatgac
    22261 cacattatta gtcattgacg atgaccggtt gcactgtgat ctcctccagg tagcgttgtc
    22321 gcgccatgga tatcgggtca gcacggcgac aagcgggcgt gagggcgtag cgatctttcg
    22381 gcagcttcgg ccggtcgtga cgttgttaga cctgcgcatg ccggaaatgg atgggctggc
    22441 ggtgctcaaa gagattcgga cgtatgaccc gcgtgccgga gtgattattc tgggaggggg
    22501 tgctaccgag gagctggaaa atctcgcacg aaaattacgc gtcacagatt tctttcgaaa
    22561 gggattgtcg ctggatgtgc tggtgggagc ggtgcatcgg atcgcccaac aggcgagacg
    22621 tgaagcgtcg gccacacagg atgtaaccgc gagtgagatc gatcagcctt ccgaggaaca
    22681 gattctcgtg gtcgatgacg atgtgatggc acgtgatctg ctgatgcgct tcctcagtct
    22741 gcgcggctat cgtgtgcgtg gggctaagga tggccgcgaa gccttgcgga tgattgaaga
    22801 gtccgcgccg gatttgttga tccttgatct tgtcatgccg gagatgaacg gcgtggagtt
    22861 gctgaaagtg ctggctacac gcgagtacgc cgggcggacc atcattttga gcggacatca
    22921 aaatgatcca ttgctggagg acgcctgggc gttggggccg caagaagtgc tggataaacc
    22981 acttgatttg gagcgcgccc tgatggcaat ccagcttgtg atggtctgtc gggaatgcta
    23041 atcttcaccg tcaacctcgg ggtgccggtg aagggtggat tgtttgcatc gcctcatccg
    23101 tttcagtctg cttgccggtt gtctcgtgcc tgcgcttgca gttgctgagc ctgtttcctc
    23161 cctaccgact atcacacatc atcagctgac gctccagctg ctgcccgact cccatcagct
    23221 cattgcgacg gatcgcctga tcctctcggg aagagcttcc ggacaggcgc tgtcgttctc
    23281 ccttgcccct acgcttcgag tcgagcgcat tcaggatgtc acgcactgtg aggccgcctg
    23341 cgaaacggct cctgagcttg ctttcgagag ggatggttca gcaggcccat ccgagccgca
    23401 gcgcgtaatt gtgaagcagc cagccactga tcggggctac ggagcggtag ccctgaagtt
    23461 ttcctatcga ggtgtggtcg acgatccgcc acgtgacccg cggcaccttc gttttgtcac
    23521 gccgagtgaa acgtccgggc acatcggacc cgaaggcgtc tatctcagca gcgaaagcca
    23581 atggtatccc gatgtggagg gttcgctcgc cacctatgat gtcaccattg ccctgcctga
    23641 cggatggacg gctgtcacgc aaggagctcc tcagtccgac cagggccact ggatagttcc
    23701 cacgaagagc gaagccttga cggtggtcgc caaccgattc gtggtgaaat cccgcacctg
    23761 gacggcaaag tcggggcaat ctattcggct ggccacctat ctctttccgg atgaagcctc
    23821 cttagccgat gagtatttgg acgcgtcggc gcggtatctc gatgcgtaca tccctctgct
    23881 cggtccctat ccgttttctc aatttgccgt cgtcgaaaat ttcttttcga gcggactggg
    23941 catgccctcc tttactctgc tgggcagcgg cgtgatcaaa cggcactaca cccagcccta
    24001 cgcgcttggc catgagattg tgcattcgtg gatcgggaac ggcgtgttca atcggatcga
    24061 tcgcggcaac tgggtggaag ggctcacgac ctatctctcg aattactatt atcacgagct
    24121 catgggcgac gaggcacaag ctcgcgaaca acgacggttg atgctcatgg gatatgccgt
    24181 ctatgtgcgc cccggagagg catatcccgt catacagttt gcccagaagc acgatgaaaa
    24241 agacaatgcc atcggctatc aacaagccgc gatggtgttt catgcgttga ggcaggaaat
    24301 cggtgaggca gtattttgga cggctttgaa acagataccg gaacgatatc tcggaatggc
    24361 ggccgagtgg cgtgatctgg agcgagtgtt ccaggaggcg gcggggcgcg accttcgatg
    24421 gtttttcgct cagtgggtcg agcgcgctgg cgtgccggac attgaggtga ctgggtcccg
    24481 ggtccagcag tccaccggaa ctgccgggga catgaacagg gtggaggcga tagtgcacat
    24541 cgcccaacat ggtaccccgt atcgcctagc catcgatctg gaattcgtac tggatggagg
    24601 acgtacccac cgaacgcgta ttcatctcac tgacgcccaa cagaatgcga tcataccgct
    24661 gcccgaacgc ccgttagcgg ttcggctgga tccagatctc catgtgtttc gccgcgtggc
    24721 gcggaatgcg ttggcgccca tgttgaatgt gtatgtcaca gacgcccatc gcacagtggt
    24781 ggtggcccca gcctccttac aacaaccggg tccctttacc gacatcgttc aacgtatcgc
    24841 cgcacaggaa gcctcgaagc ccgagccgtc tcgcaccacc gtgaaacaac cggaagacaa
    24901 gacgaagcct acgccggagg ggtcggtgct ggtactgggc gggccggggg aaaatgcggc
    24961 cgcctcggac atgctgcgat attgcggcga ccatgttcat ttcaccgaaa aaggattttc
    25021 ggtggaagga aagtcttacg aaggccccac gatggccctg ttggtatcct gccggcgaga
    25081 cgatcagcct ggcagcgtcg tgaccatcct ctacggggtg acgccgccgg cactgactcg
    25141 tgtggctcgg ctcttgtttt tttacggatg gcagagttat gtggtgtttc acgaagggtc
    25201 cgtggtagca cggggagatt gggaggatag gatgactgta gaggtgcgaa ttgaaacacg
    25261 ctaaacaggt gatggcgggc atgctggggt tgatgctttc tctttccatg acgaaccccg
    25321 cggccgccgc ctcaaaggcg gcagagactg cgacaccgac ggcttctacc gagcggcatc
    25381 tcaccaatat taagcaactc acgtttgggc ggcaaaatgc cgaggcgtat ttttcgttca
    25441 gcggcgacaa actcatcttc cagtcgacga acaattggat gaaggacacg tttgctgctg
    25501 ccatgcatcc ggccgacatc cccctgggct gttaccaaat gtatgtgatg gatctcggga
    25561 gcgagaagat ccggatggtc agcaccgggt ccggcaccac gacctgcggc tatttctttc
    25621 ccggtgatcg gcgcgtcctg tactcgtcga ctcatctacg aggccccaat tgtcctccga
    25681 agcctaagcg agagggcggc gcctaccggt gggcgctgga cgactatgat ttattctccg
    25741 ttcggatcga cggcttggac ccgcagcgat tgacgaatac cccgggatat gacgctgagg
    25801 cgacagtggc tcccaacggc aagaccatta tctggacctc gatgcgtgac ggggatttgg
    25861 atatctacgc catggatctg gacggaacgc atccccgtcg gctgacacag gaaatcggct
    25921 acgacggcgg ggcattcttc tcgcccgata gtaagcggat tgtgtatcgc gcccagcatc
    25981 cgagtaatca ggaggaactg gatcagtaca aatcactcct cgcgcaaaac cttgtggaac
    26041 cgggccgcct ggaaatcttc atcatgaatg ccgacgggtc gaacaagcag caggtgacga
    26101 gcaacggcgc gtccaatttc tctccctatt tccatccgga tgggcaccgg gtcatttttt
    26161 cgtcgaacgt ggagacgcgc aatgaagggg gccggcctga gtttcatttg tatctcacca
    26221 atgaagacgg ctccggcctg gagcgagtaa cggttggcgg gaagttcaac agctttccca
    26281 tgttctctcc ggacggaaag catctcgtct gggtgtccga ccgcaacgcg aaggagcctg
    26341 gagaattcaa cgtgtttctt gccgactggg ttccatgagc gaatcaggtg acgggcaggc
    26401 tgcgccggta tcgacgcagc ctgcgccacc gccggacagg ccgccggtcc ttgcggtgat
    26461 cctttccgcg ctggtggtgc tcgggtcgtt cgccgcgctc tttcacatcg atattcccat
    26521 cctgcggtta ctccgctcac acaatttgtc gtcgctccaa tcgttgggtg atcttggcga
    26581 aaaactgggc aacgggggga cgttgattac catcagcgtg cttctcctgg gagccgggta
    26641 tctgctcaag cgacaggcgt ggattcggac ggcggtggat agcctgcttg cccatggggt
    26701 ggtggcgttg gtggtgaaca gcctcaagca tatcatcggc cgtcccaggc cacgcctcac
    26761 ccattcaggc ggatggcact ggtggccctc gttacaatcg gggttagatt catttccctc
    26821 gggccatacc tcggcgaccg tcgccgtggc gacggtcttg gcgagagcgc tgcccaggct
    26881 ttcatgggtg ccgtttgccc tggctgcgtg ggtcggagcc agccggatct ggagaggctc
    26941 tcatttcccc ggggatgtga tcggcgggat ggtgttgggc tttatggtcg gctcaatctt
    27001 caacggacca ttgcggtggt ggggcagctc gtgcgcgcat gcgctcgtgc gcatcgcgcc
    27061 catggtgttg ttgctgacag gctggtgctg ggtggtgacg catcgcattc tcgatccggt
    27121 gaccgatacc gtactggtgg cgtcgggagt gatgctggtg ctcgcaggtt ggctagtgca
    27181 gatgttgcct cggtggcgat cgacttccgc cgggggtatt gcagccgtgg taacctcgaa
    27241 aggcttcttg ctgtcagggg taggcctggc gaccggagca ccgatcgtga tcgtgctcac
    27301 cggacttctc tgtatcgcac gatggaatgc tgcggcacag gttctcgaag cacctgccca
    27361 gccgtcctgg cgcagggatg ggctgtacac ggcggcaggt cttgcggggg tgatggccat
    27421 ccaatttctg aaaggccttg tgccattaga gtgaaaagcg ctcagtgtcc gggaatccga
    27481 atcggaggtt tctctgcctc ctcggggaca tgaatcatgg attgattggc gagcagaatg
    27541 tacccgtacc gttcgagcat cacgggatat tccatcgttt cgaacggcaa ccggttgcgc
    27601 atggctgccg gcaagagaat cagcgtccga cccggctggg tcaaataggg tttaatgtta
    27661 gcttcctcac ccttggggac gacgatcgct tttcgtttgg catagaagac cagcgagggg
    27721 cgtggctgtc catagagaat cagccggtcg tccgggccga gattcagtcc tgccacgtcg
    27781 gccagccgct gcggcggttc gatcacgaag tgattgacca atggaaacgt cagttgggtg
    27841 acggctagga ccaccaaggc taaggatcct cctgccgccc agaaggcggc cggcttccgc
    27901 gtctcgctga gcccgaaata ggcgaccaaa cccattccca ccaaaaaaat cgaggcgacg
    27961 gtatagggcc ccggtccgag tgtcacctgt ccggcaagcg gaaattcatc cactaacttc
    28021 acggcgaatt tggcatacag gggcgggagg gacgcaaagg ccagcgccag gatgtagccc
    28081 acggcggtca tcatgtggat cgcagcacgc aggtggggcg ccgcatggtc ggtcacacag
    28141 cgattccaga aggatgccgt caagatcgcg gctgcgggaa acaaggggcc gatgtagtgc
    28201 gggaggcggg tcgaagacag gctgaaaaac acgagcccac ccagcaccca ggcagcggca
    28261 aaccactcga gggcctgtga ggaggcaggg gtatccgtac ctgtcgccgg tgtgaaggtc
    28321 ccagcctgtt tcgcctcacg ccaacttcga taggcctgat accaggcaaa cggcaggagg
    28381 ccgctccagg gaaaaaagcc caggatgaac acaggcagat agaacaggag ggtgccaccg
    28441 tgtccttcca tggtgccaaa gaaacggccg atggtatccc cttgcgcgga ggtcgtgtac
    28501 cgttgcccat gcaggttcaa catcatgaga taccacggga gagccaaggc aacaaagagg
    28561 aacaggccgg gcaggagacg cccctcgcga cggaacagcg gccaggagcg agtcagccag
    28621 agatagagcc caaccgccaa tagcggaatc agaaaaccga tcggcccctt cgtcagtgtg
    28681 gctagcgcca tgccgatgta gaacaaccag atgcagtggc gttcacgtcc ctctccgtag
    28741 aggccgagcc agaatccgta gagcgacagc gtggtaaaga agatcaacac gctgtcggtg
    28801 agcgccatgc ggctgaggcc gatgatctcc agattcaaca acagcatggc cgcgccgaac
    28861 aggccgatga ccggtccgcg gcagcgtgtc agaaacagat actggagcag aatgaggcca
    28921 agaccgaaca gggcagaggg aaatcgcgcc gcgaattcac tcacgccgaa cagatggtac
    28981 gaggctgtca tcagccaata gacgaagacc ggtttggcaa agcgcggctc gtaattgaat
    29041 gtggggctga tgtaattgcc cgtttcgaac atttcccgac cggcttcagc gtttcgccct
    29101 tcatcccgat cggtcaagcc aagagagccg agtccgacaa agaacagcac ggcggccaac
    29161 gccaacaaca caacgagtgt caccggctga atcgaccggt cgatcggcgc cggcgtctgc
    29221 aaggacggga cttctccgtt catctgaggt tccattagga tttgatcgcc ggggaagccg
    29281 tgctggagtc ggccgagttc gggcgatgaa tgagcatgag gttgcgaagg tagacgatac
    29341 tgccgatgct ctgtccggca atgaagaccg gatcctgccg gtagatggca tacgcgaggg
    29401 tgatcaagcc gccgatcatg ctcatatacc agaaggccgt cggcacgcgg ctttcagcat
    29461 ggcgttcgga ggcgatccac tggaccaccc agcgcatgaa gaagattccc tgtccgagga
    29521 atccgataat cagccaaatg gtgtcgagtg tcatagtggt acggaggccg aggtcgatcc
    29581 ggaaggagat gttgttgcgc cccggtagtg ataccgcagg cagcggtgct gcatccatcg
    29641 cacagccacc aaatcgtaca accctttgaa cagacggttg cctacaccat atttcgaggt
    29701 tccgcgtgtg cgagggtagt ggcgcaccgg tacttcggtg accgtgaacc cgtgcatcaa
    29761 ggccagcgcg gggaaaaaac gatgcatgcc ctcgaagagc tgcatttttt ccaccacagc
    29821 ccgccgaaac agcttcagtg agcagccggt gtcgtggacg cgatcgccgg tgacggcgct
    29881 gcggacgctg ttggcaatac gggacgaaat ctttcgtgtc agattgtcgt ggcggtcttt
    29941 tcgccaccca cacacgagat cgaaggtgtt gatgtgcggc agcagcgtgg cgatatccgc
    30001 cggatcgttc tgcagatcgc catcgatggt catcaccagc tctcctgtcg accgcttgaa
    30061 tcctgcatcg aaagccgccg attgcccgta gttgcgatcg aaatgaaaga ccttcacggt
    30121 ttggtaccgg gccgccaagc tatccaacac gtctgaactg ccgtccgaac tgccgtcgtc
    30181 gatgaaaatc aactcgaacg gggccgatcg cgactcttct cggccgtcca ggaccttcac
    30241 caattgctct gtcagaggga ccagattgtc gcgttcatcc ttgatcggga tgacaacgga
    30301 agcccatggg cgggtagcca cagtcatgga gcggggtcag ttcctttacg cagccgttga
    30361 tcagtgtgca cggggcacat tctacaaaac gcatggaggg gtggtcaaac gattctgtct
    30421 cgttcagtgc cgttgccggt ccatgcgaat cgggagccgc tactcgatgg acacctgccg
    30481 atcgacatga gtcgagaagg taggatcgtt cgacacgaag atcaccgacc agggttcgtc
    30541 cttcgcgcag agccggcgga gtagcaggtc tcttgtggcg ggcagcatat tgtgcaacgt
    30601 gccatcgaaa attaagattt gcgggcgggt cacaatcgcg cgggctacca ggaggcggag
    30661 aatctgactc atcgagaggt gtgtctgtcc actggagacg ggggtgtgca gcccttgtgg
    30721 catcgcatcg atgtcgtggt ccagctccac aaaacgcagg gcccattgga gatcctggta
    30781 ttcgatggca ggtcggccca gcgtgatgtt gtcttccagc gtcccgtcca gcagcgtcgg
    30841 atgagaatcc aggatgagtc cgcgtacccg gctgatggag tcgcgcctca cttcagcgag
    30901 attcatgtcg ttgtaccgga caaatccggt cgaaggtggg tgtagaccgg ccaggacttt
    30961 cgcgagggcg gttttggccc tgttggtgcc gcacaggatg gccacgttct ctcccggcgc
    31021 gacctcaaga gacacgtttt gaaaaatcgg aaggccatcc tgcgccctgt aggaaaggtt
    31081 ccggcaggtc aggtgaattc ccgattctcc gaactgtgtc gccggcacgt cttccttcgc
    31141 gccgtcttct tctgtcggca aggagaacac tgcggccatt tcccggcagg acacgaatgt
    31201 aaaaaacatc gcgaccatgc gccgagccaa ggtgtccata ttcagcagga ggttgccgac
    31261 cagcacctcg gcggcggcaa attgcccgac cgtcagttgt ccatcgacga ccaggagtcc
    31321 cgccgtgatg agcagcccgc tatggccgac gacttgccac agggccgcgg ctttgtactg
    31381 ccgtccggtg agcgtgtcag accgccgttg ccggattctg gcatagatgc gtgtcagcgt
    31441 atcggtgcgt tccaggaggt acggactatc cccggccgct cgcaggtggg gaagattgtg
    31501 cgagatattc tgaatccagc cgaatatctc atagtgcaag cgggacattt ctagggtgat
    31561 aaagaatccc ccccgcccaa agatggtgag taaccccaca aacccgagaa tcagcaccag
    31621 aatgtagagt acgaagtagg gatgaaacag gatcagcatg gtcatcccga tggtgccgac
    31681 cacagccacg ttaaagagat ccgcgaccat cgcgacgagg gcgcgcgtca gcagatcggc
    31741 ttccatgaac cggtgggctt gcggcgtggc aaaggtgtcg tcgcgaagct gcgggagaag
    31801 gcgcgtgaag gcgatggcta cgcgcgtata gatccgctgt tgcagcgtct ccacggcccg
    31861 cgcctgcagc acgcgaaagg ccgcgacgcc cgtcaaggaa ctggcgacga acagggccag
    31921 cgtgaagatc atgcgaggtt ccatcgcaaa ggagaaagta ctgacgagct cctggacggc
    31981 aatggggacg cagaggagga aaaacccgat ggccactgca tacgaggcga tgatgcccag
    32041 gatggatcgc tccagcctca gcaacatgcc caggtgggcg aaaatgtcgc gaaggacctc
    32101 ggtcagctga tactggggat agggtggtgt cgttgcgggg gaccggttca caaacaaact
    32161 cctaccgcgt gggcgctggt aggagttatc agccgaggcg aggatcgcac tcggcggttc
    32221 tcggtgaact ccatcaccgg agagaatata cggctgggca aagtctagac tgagagcccg
    32281 tttcccgtca acacaaagcc ccttcggata cgcgacgagg cctggcgact gacaatgccg
    32341 ctggcgaatg accccttgcc ggtcatcgga tgaagagaga cttgaagatc agggccgtgc
    32401 cggacaggaa caaaaatgcg gcgaacgtgg tgcggtatcg ttctgtgctc atcttactgt
    32461 agagcaagag ttcggtagcc aggaacatgc tgacgcctac agccatatag agtgccgtgg
    32521 tggatgtggc aatggcagaa ggcccgaggg acatgctcag cgtgatgagc tgaaacagcg
    32581 cgaaggttcc gtaggagacg gccgttgtcg cccgggtctg atccttatcg tacggtttgc
    32641 tgtgaatcat ggctgtcaac agtgagccgc ccagattggt caggccgtgg acgatgccca
    32701 tcaccgtgaa gtagatgcgc tcatatcgca ccagcgattc gatgcatctg ttgaacggcc
    32761 catagacgct cttcagcgcc gcgacgatca aaaacaggcc tacgatgctg ccgatgttca
    32821 gcttcagcgt cgtgaccaat aagaggcaca gcaccacgca ggggatagac agggtgagga
    32881 tctgccgata gaacggccac tggatatacc gatagtcctt gctgacttgc aggaggttga
    32941 tggtcagcga aatgggaagc agaattgtca gcgcggtgat gaagtcataa ccgagcacaa
    33001 gaagaatcgg ggtgccgaag agcaacacgc ccacaccaaa gagcgactga atggttgccg
    33061 tgaggaggat ggtggccaga atatcccact gcaaggcgac gacgttcctt tcgaccggca
    33121 ggcgccagaa ggcccaggcg cctggcattt gcggcggcag accggtatag cccagtggta
    33181 gagcagccgt caatcgctct gacgcgtgcg ggtttggtca ccggcttctg gcggggactt
    33241 cggattcaga tgcggcagtg atcgtgaagc gcatggtgcc catcaggctc atgtcgttga
    33301 tctgttcgcc ggcatggatt tccactttat accgccccgg tttccaaccg ctctctgtcg
    33361 ggaacaattt caggtagccg gtttgatctt ccagcgcgat gtacatcgca tcttcagcaa
    33421 ctacgacttt tccatcgact ccggccacct cttccggata gcagcgcccg aagacctgga
    33481 aggattggta gtgctggtgc agttcaaaca cgataaaaat cggtctggcc ccggcggaga
    33541 agcgttcggt cggtttgaca ggaacaattt catgggtccg ctggaagccc aattcttcat
    33601 cgaacccttc ggcgagcaca atgtgacgaa acatgccttc gggcggggcg tcgaaattgt
    33661 agggcttggc gctctcggtg cggttttgaa aatcaggaat gggaacgttg cgagtcaagg
    33721 gaagatcttc ggcccataag agagagccgg agaaaagaag gatgggacag acgagcatac
    33781 acgccgatct catcctgtct tggtacactc cgcccgggag gcctgtcaag gaaggcatac
    33841 agcgtcggaa ctcggtcggg gcgttcaccg aaaggcatca tgaatgctga gggggattcg
    33901 tccggaagag gttgcgggtg aaaattgctt cctgttagac tttccctctt tctacagggg
    33961 gacagaatgg aacagcacct catgacaccc gtcgaggatc ccgacgcgtt accgcagccc
    34021 atcggggaat acaagccggt cgattactgg caggcgcaca tcaatactct gttctatcag
    34081 ctgcgcggtg atcaacaacg cagcttctat cagaccttcg cctcggccga ttatcggttg
    34141 gcccatgcgt tggcggccga ctatttcgag caggcagtca aacgtgacaa gaaggctgcg
    34201 gcgaagtctt ctgcctccgg cgatgccgct tcccgaccat ccttgaccgt catggaatgg
    34261 ggccccggta acggcaacct cgcggcctgc tttctcagtc atctacagaa gctcgacaaa
    34321 gcggggcaga tctatccgcg ggtgcggtat gtactcgtgg attctcatgc tcctgctctg
    34381 gagcgggcac gcacgcatcc ggatttgatt ccgcatctct ccaaggtcga gtccctctgt
    34441 gccgatgtgg acaatatgtc gaccatcgcc gacggtacgg tcgaccggat catctgtaat
    34501 gagatgtgga atgaattggc caccaagctc gtggtgaaga agggggggga atatgaggaa
    34561 gagcatctcc gcccgaacct taacgagcgc aaggcggcag cgattgccga ctggtccgcg
    34621 tttgtgcgcg ccttcgacgc caaggacatc gaaaaattga aacagttccc gccctttctg
    34681 gacgatctca tctgggagcg cgaatatcac aaggtggatt ggaaggatgt gccttatcgc
    34741 aaaaccctga cggagtttat gaaggcgatt gatgaagaag tgctcgtgcc ggtcaatctc
    34801 ggtgccttcg ggtcgatcaa ggaagcgaag cgagtgctgg ccccggacgc cgtggggttc
    34861 agcagtttcg atgcgggaac agcggacatg caggtgctca atgatcccga gaagccctgc
    34921 tatggccagt tcggcggcca atacagtttc atggtgaatc tggctctcat tcaagccgta
    34981 gccaagcatc tcgggatcac gaccaccatc attgaaaccc agcgtgagtt tgtgggaagt
    35041 cgactgggaa ccaatgtcat gacgctgatg gatctcctgg cctgtcatcc gacggtgggc
    35101 tctaaggttc agccctggca attggatcag ctcacgctga aaacgatccg taccctgaat
    35161 gaacattacg agagcccgta tcaacgcaag atcgagtttc ctctgcgcag cgaaatgcct
    35221 gcggaagaac gcgaagcggc acagggcacg ctcctctcga tgaaacccaa cggcattccc
    35281 gacaccatcg cgtatgtcac cgaagaagaa ttgagtcagg cacagggtga tttggaacag
    35341 ctcggatacg agcgggaggc ctggttgatg gcgcttggag cgcctccgag tccggttgag
    35401 tactatcatt tcgcgttccg accgtagtcg ctggttcggg caggagggaa agagacgtaa
    35461 gggggcacct gtaggagaaa gagcttgact aattccagtc gtttctatag cctttcccgc
    35521 gatttccgat actgaccccc tccttctccg tgcgtgggga aaattcagag gagatggggt
    35581 tcgcaggcaa gatcttctca gacgacgtac ttcacgagtg gcagtcgagt cgccggtgcg
    35641 tgaacatatg tcgtgcgaat aatcgcacag ctgtaacaag gagcatacag taccatgttt
    35701 ggttcgttcg gctggatgga gctgctgctg attctcatca tcgtgctcat catcttcgga
    35761 gccgggaaaa ttccccagct cggtgaggga ttaggtaaag caatcaaggg gttcaagaaa
    35821 tcggttcacg aagcggatgc cattgatgtg acggcaaacg agacggaacc agccgcggct
    35881 cagccgacgg cacaaatcca gcaaaccgga cagtcggccc caccgccgcc tgcgcagcag
    35941 gccggtgcgg ctccaccgcc acggacgacg caggggtaac ttgcgtgact gaggatcaga
    36001 cccgggtgac ggccattgtc tttcacggtc gcgctgcctg gtctttcaca caaccacctc
    36061 agtaggaaca ccatgttcgg tcttggcgct ggagaaattc tcatcatcct ggtcatcgcg
    36121 ttcctgttgt tcgggcctaa gcagttgccc gaaatcgggc gtcaggtggg caaggccgtc
    36181 aaggggttca aagagacggc ggacgacctg aagaagacgg ttgagcccga actcaacatg
    36241 atccagcagg aaatgaagat ggtggaacaa gatttcgagt cgtcgatgaa agaagcagaa
    36301 gaacagatca accacgcaac atcgggcgta gagcatgggg cagaggaatc gggtttgccc
    36361 aagcaggcct aataccattt catattcgct ctacggctgt gaagggaggt gaccacagca
    36421 acaatacaag actgacagtg tgagggactc gcttcgggat tgaagcaggt catgaccgaa
    36481 tggtgggcac cattctggtt cggctgactg aggcccccac atacgagtta gctttgtagt
    36541 gcaatagcgg ttggatttta ggcggcaccc agagtgaatg ggtacacgaa gggttgccat
    36601 ccaattcaca ggaggaacgc tatgaaacgc atccatggac ggaccagatg gggccggttg
    36661 gccgccatct tcggcgctgc ggcaatctca gctctgcagt gccttacgct cccggccttt
    36721 gccggattcg aacttccccc gggcgaacgc atcacgaatc tccccgcaat tcctcgcaac
    36781 atgccgcaga aagaagcgta cgaactgtac gatccggtca tcggccggaa tttcgacatc
    36841 aagaatctgt ggatgcgcgc cgatctgcgt gtgcgtccgg aaatgcgaaa caacgggtgc
    36901 tttggcctgc agatgaatgc caacgggacc tgtaacacgt tcggaacgcg tggtgcggct
    36961 ggggctggtg gtaacaaagg caacgatttc tttgtccagc aatggatgcg cttgggtatc
    37021 ggttatgatc tctcgcccga tgtgaacttc tacgtggaaa tcattgacag tgccacgtgg
    37081 ggtggcaacg gtacggcgac taacgcaggc aacggcggag atccgcttaa ccacaattgc
    37141 tcggcgacag caaccggtgc ttgccgattg ggtgttcgtg ccgcctacat gttggtgaga
    37201 aatctggccg atgtgcaggg cttgagcatg aaggtcggtc gacaatatgt agtcttcggt
    37261 aaccactcat tgttcggcca cttcgactgg gcgaacaccg gctactcaca tgatggcgtg
    37321 atgttctcct acaccggaat caagaactgg gacatctatg ccggttggtt ccgtaattcc
    37381 gaatcagacc tcaatcaggc tgctgctgta ggcagtggaa gcggcaacat tgccggcaac
    37441 gcaagcggca gcgatgccaa tcgtgatgcg gacatgatcg ttttctacaa tcagctgaaa
    37501 atgattcctg gaatggtcat tgagccgttc tacgtgtatt acaaaaacaa ttacggttca
    37561 tcggctacgg caggggtcgg aaaccaggca tttgggctgg gtaccgcaaa gcatgccaac
    37621 cagactcggc atatgattgg taatcgaatt gaaatgagga agggtggatt cgacttcagc
    37681 aatgaagttg cctggcagtt cggtcagatg gggcaagctg gcgcttgtgt gggcgaccag
    37741 aaatgtttgc atatcaatgc gtgggcgacc agaaactgga ttggctacac gttctatgac
    37801 acggcgtgga agacccgcct ggccttcaac ctcgattacg cgtctggcga cagccggaac
    37861 aacacctgca ccaacgggac caattgtaag acagccaaca cctttgaaaa cttcttcccg
    37921 acgaaccaca tccacatggg ttacatggac gtgcaagcgt ggaagaacat gctgtctcct
    37981 tcagtcaact tgcaggctcg gccttcggcg cgtgatcaca tcgaattgtg gtacacgaac
    38041 ctgaacctgg ccaattcgaa ggactgttgg tatcgagcct cgcaggggtg ttacgtgttc
    38101 tcgaacgcca acaacacgaa gacccacatc ggcgacgaaa tcgacgtggc gtacacccgg
    38161 atgttcgccg acggcaaagt tgccctgcag gctgcatatg gcacgatctt cagcggtggc
    38221 tatttgacca gcacgttaaa tcaacaggtc aatcagcact gggcctatat gtcgctgtgg
    38281 atgaacttct aggaaaaagc gatcaggtta cagctttcag ctgacagcgt ccttgctgat
    38341 agctgatggc tttcaccaaa ggagacacgc aatgaagaaa ctcatgttcg taacgctggg
    38401 cgtcgcagcg ttggcgatcg gcagccagcc ggtcactgcg caggcccagg tcgcggatgc
    38461 gattcaagca gtgaacgatg ccatcgtcga gttgaccgat gcgccgggcc tcggcaagcg
    38521 gacgaccgtc gatgtgacga agcggtgggg ttccgaccgg tccgtcatcg acagcgccac
    38581 ggcgaaattg caggatgggc tgagcaaggc ccagtccggt ggagtcggcg ctgatgcgat
    38641 gcgtcagctg aagctggcgg tcgattatgg gaaagcccgc atgcacaagg aagctcgctt
    38701 gtccgcacag ggtgccttgc gccacctgtg cgttgcgaat caagatcagg gcccaggctg
    38761 cgacacggtg ccgaagttcg gcagctacac cgcgccatag gtagaactct ggtgatcttc
    38821 gaggtatgag gggagatccc cctgtctgtc tcgagtctga aaccccgccg ggtgatcccc
    38881 ggcggggttt cttttttgag gcgactgact cttcgctgat gtcttcggct gatgattgat
    38941 attcgatgta acctgacggc gagcgactcc tgctgcttgc ccgtgattcg tcggacgtct
    39001 tatactcggc cgtccgcaat acgcaaagta gttccgttct gagtgttccc cgtgaatgac
    39061 ctaagtacac agcttcatca acaattcgga ttttcatcat tccgcccggg ccagcgggag
    39121 gtcatcgatg ccgtcttgtc tcgacgcgat gccatggcgg tgatgcccac cggccagggc
    39181 aagtcactct gttatcagct gccggctacg atcctgcctg gcctgacact cgtcatttcc
    39241 ccgttgatcg ccctgatgca ggatcaggtg aacagtctga aagcccgcca cgtggccgcc
    39301 gcagcctttc attccggcct ctctgaaccg gagcgtgaca agattgtcct caatcttaaa
    39361 ttgagacggc tccagctcct ctatctcgcc cctgaacgga tgcagcatga acggttcctg
    39421 cgtcttttgc gatcgttatg ggtgtctttg ctggtcgtcg acgaagcgca ttgcatttcg
    39481 caatggggac atgatttcag gccggactat ctgaacatcg gccgcttgcg ccgggaactc
    39541 gaaaacccgc cctgtttagc cttaacggcc accgccacgg cgcgcgtgca agcggatctc
    39601 tgcgagcgac tgtcgctcca tgatccatta cggctggtca ccggttttcg ccggccgaat
    39661 cttgccctct cggttcgtca gtgccgttcg cgccaggaaa agctggctca attggagcgc
    39721 gtggtgcgcg agtatccgac gggcacgctc ctcatctatt gcgccacgcg gcgcgcggta
    39781 gaggaagtgg cggcctgtct ggggcgctcg aattcgtctg ttgggtacta ccacgcaggt
    39841 ctaacggatg aagagcggcg atcggttcat gaggagtttc gcgtcgggac gatccggata
    39901 ttagccgcga ccaatgcatt cggtatggga atcgataagt cggatgttcg cctggtggtg
    39961 cattttgata ttcccggaag tctggaggcc tattaccagg aggtcggacg ggccgggcgt
    40021 gacggccacc cggccgcctg cctgctgttg ttccatgagc gagatgtggc cacgcaggaa
    40081 tacttcattc aacaggcctc gaaagaatcc ggcaacgcag cccgtgtgga acgcatgaag
    40141 acgttgctcc aggatttgct ggactatgtg gccgggacga cctgccgcca actcgccata
    40201 ttggactatt tcagtgatga ggtggagcgg gcgctgggcc cttgcggatt gtgtgaccgt
    40261 tgcaagacgc caatacagtt gcctgtggac gtcgtaaatg atgagtcgtc gtgcgccaag
    40321 gccattctta cggcggtctc ctggtgcggg gggcgattcg gagttacgcg gattgtggaa
    40381 atgttgcgcg gcagccggtc gaaggggctc ctggcccatg gggctgaaga ctatccggga
    40441 tatggaatct atcagacctg gaccaagacg gcactgactc gtctggtgaa atccttaatc
    40501 gacaccggac atttgcaggt ggaagggtcg gaatatccca cgctcgactt gacgcggcgc
    40561 gggcaggagg tggtgacggg cctcagacct gtagaagtga agacggcggt gcagtccccg
    40621 gcttcgtcgg cgtatcagac gccggtcaac ggcccaaaca actccatggc cgcatcactc
    40681 acgtcgtccg ttgatccgca gttgtttgaa cggctccgtc aattgcgtaa agaactcgcc
    40741 gaggaagagg gcgtggcgcc cttcgtgatt tttcacgaca aaacgcttcg cacgatcgcc
    40801 ggccataaac ctgtgacgtt gagcgccctg ctggagatcc ccggcatcgg cgaggttaag
    40861 gtggagcggt atggccggcg cgtgctcggg atcgtcaacg aggagtgtcg gtaacttctt
    40921 ccgtgttgta tcgtccgcgt ttcattctgc gttcttatta agccttcagc cctcccgcct
    40981 tacggaattg ctcctgcaat tccgcatatg tcgtcgtcac aggaaattgc gggaattctt
    41041 ttggcagatg agccggggga cgaaagaaga atccggcatg ggcctctccc agcatggcgg
    41101 tatcgttgta ggcatcccct gcggccatga cgcggaaatt caggctcttc agtgcagcca
    41161 ccgcgtgttt cttctggttg ggttgccgga gtttgtagct gacaatgcgg ccgttggggc
    41221 cgatttccag ttgattgcaa aaaatggttg gaaagcccag ttggcgcatc agcggaaggg
    41281 cgaattcata aaacgtgtca gacaggatga tgacctgagc gcgttcgcgc agccaggcga
    41341 taaattcggc ggccccttcc atcggcccca tggcatcgat gaccgattga atgtcggcga
    41401 gggtgtatcc atgctcatca aggatcttca accgccgcgt catcaaggca tcatagtccg
    41461 gcatttcccg tgtggtgatc ttgagttctt caatgccggt cttaatggca aagttcaccc
    41521 agatttcagg aactaagacg ccttcaaggt cgagacacac aataacggga ttctgcattc
    41581 attcctccgg aaaagtcgta catgtgaata gtgatgggac gagggagcgc tcgcacacgt
    41641 cacagcgaag aacccccaaa tctgtctgtt atccgccgct tccgcgccga gccctttcct
    41701 gaccgagata ccgcccgatt ttatcgatcg ccttttcaaa tagttcggtt ccggcccatt
    41761 ggcgggcctg ttcggcctga tggcgtttgg cccagtcgat ggccagcggc agggggatca
    41821 gcctgggtgt ggtggccgtg agatccgccc agagtaaact cagcgccgtg ctgatgcgaa
    41881 ccgcaacggg aaccggccgg attgtctgat tcgtcatgtc ctgacagtcg gcagccgggg
    41941 aggtcacggc gagttcccgg caggctgccg gtcggtcatc gtagatgcta caggcctcat
    42001 tgtccagaaa agggcagggc atgcgaagcg cataataggc ccggttgagg ggttcgatgg
    42061 cttcgtcact gatcgggtct gaagattcag cgagtgcgga gagttgttgc aggattccgg
    42121 cgcgagccag gcgttgctga gtcacgtcaa tttttgacag gagccgatca cgctccggtg
    42181 gggccaggcg atcgatgctc ttcgcgaggg cgaaggcttc gggagcggaa atcggcacca
    42241 gcatgcgaca acaggccgcg cagcccttct ggcaggaaac agtctgcccg gcgtcacgca
    42301 catgggcgag ttccagcgtc tggacctcct cgcctagtcc gcgcatgagg ggaaggattg
    42361 ccgtcaccgg cacgaagctt gttggaactc caatggcggt ggagacctca ccgaccgggg
    42421 tttgcaggga gatttcgaag tgttcgactg ctgtctggtg agtcacggtt ctcgcgtcag
    42481 ctcatttctt gcggtcatca tcggagataa aagcccgtat gggcgttgct gcagctatca
    42541 tagagaacca tagaatcggc ggtcaaccaa tgggcttgga cgccggtctt gccccacggg
    42601 gacggttgcg gctactctgt cgtcgatgcg ggtatccggc catatcatcg gtttgttaaa
    42661 agaatatatg cgtgatcttg tcgagc
//
LOCUS       DAOQPD010000026        40995 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_388_length_40995_cov_21.226234, whole genome shotgun sequence.
ACCESSION   DAOQPD010000026 DAOQPD010000000
VERSION     DAOQPD010000026.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 40995)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 40995)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40995
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_388_length_40995_cov_21.226234"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..260)
                     /locus_tag="PK063_08200"
     CDS             complement(<1..260)
                     /locus_tag="PK063_08200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-deoxyribose-5-phosphate aldolase"
                     /protein_id="HMZ97069.1"
                     /translation="MGLVSWNENLPALLDHTVLRPEATKADVLRLCAEAKEQGFVVIF
                     VPPCYVDEAVAAVAGTAVQVGIPIGFPLGGHSTHAKVTEAIEA"
     gene            complement(346..1359)
                     /gene="mltG"
                     /locus_tag="PK063_08205"
     CDS             complement(346..1359)
                     /gene="mltG"
                     /locus_tag="PK063_08205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HMZ97070.1"
                     /translation="MVILLALSGYLVLRWAQSPVASGLPKPPSKIVTIPDGSTFQQVA
                     GMLKSEQLIRSRWAFLLLGRSHDSDRKIRPGEYELDGGMSPQDILSKLLAGRVVLHPV
                     TIPEGYNLAQIAEVLAGQQVTDAKEFSKLVRDRTFIATLGIEADSLEGYLFPETYSFP
                     RQAKARDVIKAMVDGLHRVWSADLQEQAARMKLSLHQVLTLASVIEKETGSKEERELI
                     AAVFHNRLRKKIPLQSDPTVIYGLPAFDGNIHKRDLSVMSPYNTYRVQGLPPGPIASP
                     GAHSLRAALFPAQASYLYFVSRNDGTHQFSSTLAEHNLAVEKYQKQPFRKRARGSLVT
                     HGA"
     gene            complement(1283..1894)
                     /gene="ruvX"
                     /locus_tag="PK063_08210"
     CDS             complement(1283..1894)
                     /gene="ruvX"
                     /locus_tag="PK063_08210"
                     /inference="COORDINATES: protein motif:HMM:NF015607.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HMZ97071.1"
                     /translation="MKGQRILAIDHGSKRIGFALSDELGWTAQPLETFHRRNPEADIR
                     HIQELVREHEVGRVLVGLPLRLDGESGPAAKVVEEFIQLLEPALSVPVVTWDERMTTC
                     AAEDLLIAADVGRRKRKGIVDRIAAAILLQSYLASLEKPSTSQEQAISNSHEDDPWSF
                     DEPRVDDAEAIDCGTGSSDGDTLGPLGLSGPALGSKSRRQRAS"
     gene            complement(1899..4529)
                     /gene="alaS"
                     /locus_tag="PK063_08215"
     CDS             complement(1899..4529)
                     /gene="alaS"
                     /locus_tag="PK063_08215"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HMZ97072.1"
                     /translation="MSQSVNDLRRAFIRYFEQQGHRAVPSAPLIPQADPTLLFTNAGM
                     NQFKRVFLGEETRAYQRAVTVQKCLRAGGKHNDLENVGYTRRHHTFFEMLGNFSFGDY
                     FKEDAIRFGWEFLISVVGLSKDRMWITIFREDDEADRLWRKIGVSPSRIVRCGEKDNF
                     WQMADTGPCGPCSELHFDQGPSVPGDDTPNGEGDRVIEIWNLVFMQFNRDSAGTLNPL
                     PKPSIDTGMGLERLTAVAQGRLSNYDSDLFAPLLAAIGRRAGAEYGAVEQSDRSMRVI
                     ADHLRAITFLMADGVLPSNEGRGYVLRRILRRAARHGRLLGITEPFLHELTATVVDQM
                     GEAYHELRPAAGTVAEATRGEEERFIATLDQGLPILNDMLSKVKTSGQHVLQGTEIFK
                     LYDTYGFPMDLIAEACREQGITLDETGFEAAIEEQRTRARKTGGFESETARPALSDVA
                     ARVGTTAFVGYDRLDSEGVVQALLQSDRLIKEAREGDEIEIVLDVTPFYAEGGGQAGD
                     QGVLSGTDGRVEIRETTRPVPTLIVHKGVVTSGSIREGERLQLSVNPRTRKDAARNHT
                     ATHLVHAALRDLLGPHVKQYGSLVAPNRLRFDFAHFRPMSSRDIDEIESIVNEQVRLD
                     QPVQTDVMGVQDAVAGGALAFFGDKYGDRVRVVQIDTFSKELCGGTHCGRTGEIGLFR
                     IVSESGVAAGVRRIECLTGSGALDSLKRLEADVREMSELLKVAPTEVVARTRKLSEQL
                     KDKERELADVKLKMASTSSGDAQAREIKGVQVHAQRTDGLDVNGMRALADQLRDKLRS
                     GVVALGAANDGKVSLLVVVTKDLVGRLKAGELIKAMATEVGGTGGGRPEMAQAGGKNP
                     EGLGPALEKVFGLVQKALEG"
     gene            complement(4526..4972)
                     /locus_tag="PK063_08220"
     CDS             complement(4526..4972)
                     /locus_tag="PK063_08220"
                     /inference="COORDINATES: protein motif:HMM:NF014668.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RecX family transcriptional regulator"
                     /protein_id="HMZ97073.1"
                     /translation="MDFLTMAIRYLGRAERTASQVQHYVQEKGASRVQGHAVVRELQR
                     RGYLDDQAYATRWAEARLSRRPMGRERLKLELLRRGFEDTVAERALCSAYRSVSEQEL
                     ACQALEGRTTRMRPLQWVRFLRQRGFDDDTIQQVTQVDLETGLDEL"
     gene            complement(5023..6135)
                     /gene="recA"
                     /locus_tag="PK063_08225"
     CDS             complement(5023..6135)
                     /gene="recA"
                     /locus_tag="PK063_08225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HMZ97074.1"
                     /translation="MSEKDEKKRALDLALAQIEKQYGKGAVMKLGTDDRPADVPAISS
                     GSLGLDIALGVGGFPRGRVIEIFGPESSGKTTLTLHAIAEAQKAGGVAAFIDAEHALD
                     LTYAKKLGVHTDDLLVSQPDTGEQALEIAETLVRSGAIDVIVVDSVAALVPRAEIEGE
                     MGDAHMGLQARLMSQALRKLTAAIAKSQTTLIFINQIRMKIGVMFGNPETTTGGNALK
                     FYSSVRLDIRRIESIKDGQDVTGSRVRVKVVKNKMAPPFRQAEFDIMFAEGISKSGEI
                     VDMGVEKRVVEKAGAWYSYKGERLGQGREAVRDFLKTNPAIAKEIEGKVRELAGLPLR
                     GAEKKAEAKEAKEEKPERKVEIRQDEKRGHSARVTS"
     gene            6689..6952
                     /locus_tag="PK063_08230"
     CDS             6689..6952
                     /locus_tag="PK063_08230"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97075.1"
                     /translation="MPQQHMDDHSGQSAVQLHVPAARAPRDLTYDEKKAAEAAFRGEP
                     FNPAWSAAAAVVYEGIVSAMCRMQVASLTDMEAVSVAEECLTR"
     gene            complement(6991..7608)
                     /gene="thpR"
                     /locus_tag="PK063_08235"
     CDS             complement(6991..7608)
                     /gene="thpR"
                     /locus_tag="PK063_08235"
                     /inference="COORDINATES: protein motif:HMM:TIGR02258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008664 - 2'-5'-RNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2',3'-cyclic phosphodiesterase"
                     /protein_id="HMZ97076.1"
                     /translation="MIRAFLAVELPPDFRAALSVIQQDLKRRLEPAVGRQARVSWVQP
                     ASMHLTVRFLGETPQEVIESLHAVVSEVVANHHMIEVPFSRLGTFPRIQQPRVLWAGP
                     LESWEQGSHGQRLQVLYRAVEEVCREAGLAAEVRPFSPHLTLARIKEGERQVGQVLAQ
                     SGALDQPVTIGVLPIKALVMMRSELHPAGPVYSKLWECPLAASAA"
     gene            complement(7605..8888)
                     /locus_tag="PK063_08240"
     CDS             complement(7605..8888)
                     /locus_tag="PK063_08240"
                     /inference="COORDINATES: protein motif:HMM:NF001813.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HMZ97077.1"
                     /translation="MNKSKAWTAETIAIGSELLLGGRMDTNSLFIADHLATCGVELRY
                     KSIVGDELSDIVGVLKTAARRVRVVIITGGLGPTIDDLTREAVAQATGQRLSRRKTAL
                     DGMIARLAEWGRTPTKAQLRQAMIPAGGEVLTNPVGTAPGFALIWKDTFFAALPGVPR
                     EMEPMIQDGVLPRLQAWIGKHKGIPATPVIRRVLHTSGVPESIVDQRLEGLLPDGTAI
                     QLGIYASPMEVMVSLTGPEKESGPVTIDRLFEDAKTRLGDIMYGEADETMETVVGRLL
                     TDQHLTLALAESCTGGLIGHRLTQIPGSSAYVDRGVVSYSNRAKVELLGVSQDLLDRH
                     GAVSAEVAAAMARGIRERSGVSVGLSVTGIAGPGGATKSKPVGLVYVGLDGGPGENLT
                     KEFRFHGGDRSVIKQRSSQAALDVLRRWLITKGGG"
     gene            complement(8935..9549)
                     /locus_tag="PK063_08245"
     CDS             complement(8935..9549)
                     /locus_tag="PK063_08245"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97078.1"
                     /translation="MRTIRRRCAGFKLALYLFVVAGTGPPALSLAIEVQPTPEQIQAT
                     MERGKTAAAKGASPDQLHEWFGAKEDLTPHGFIMTKLGSLLVMANHLSLRALSPTDQD
                     VAQVMANGNLLVNVVLFGDRVNFAADSYIVLEQAGRTVKPSSVRFDARGERTSVWPQQ
                     PAYRAKVIAQFPYADLDPHAKTTLSVFPSSGGQVTFELDFAHIE"
     gene            9695..10402
                     /locus_tag="PK063_08250"
     CDS             9695..10402
                     /locus_tag="PK063_08250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chlorite dismutase family protein"
                     /protein_id="HMZ97079.1"
                     /translation="MSSPEQAPRRQYVNFTFYKVDPAWRRLPEDERTRGKQEFLRAVE
                     EYQGKVLVIAYTSVGIRGDCDLMLWRISYELELFQEMSTKILASGLGKYILNPYSYLA
                     ITKRSIYVDNHTHENQESKRLTVVPGKAKYIFVYPFVKTREWFLLTKAARQGMMDEHI
                     EVGHRFPSVKLNTTYSFGLDDQEWVVAFESDKPEDFLDLVMALRETEGSRYTLRDTPI
                     FTCIRKSLKEALDTLGG"
     gene            10511..11173
                     /locus_tag="PK063_08255"
     CDS             10511..11173
                     /locus_tag="PK063_08255"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97080.1"
                     /translation="MSVEAQTHPASDYRAAVYSAILPGLGHLLRGRHKAAMFFGFITI
                     LLIILSLGLGRVSGRAAEVFFFMLLALPWWALQSYDAALGPAASGSDLVRTGRLAWAE
                     GHDIRFLGLLFLVSAANDAIIIAKNPDYLLPFFCTKLDGAAGFVTKALSPFLHTWVGY
                     GFLRIKKWSLLVYLVYAAYGTTNALVNLTCFGPGRIRNTLLIALIAFTSYILWRRRMF
                     QR"
     gene            11277..11489
                     /locus_tag="PK063_08260"
     CDS             11277..11489
                     /locus_tag="PK063_08260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97081.1"
                     /translation="MAENNAVYAIRHPDGSVTLYIDEEYAIDRGVDPAKLVRVEIPRE
                     LFVSGSIQHIREYVAVYLENSHQGTA"
     gene            11522..12691
                     /locus_tag="PK063_08265"
     CDS             11522..12691
                     /locus_tag="PK063_08265"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97082.1"
                     /translation="MSALLTSELIASTIEQAPIQGRVMLKLLLLQHFDITPEEISYIA
                     ADRPDPRCVAGSKPIHQMVKQDALRDVTNRRDEYRRRVRLRRERLWLQMEAMKGMIAL
                     AEGMIRAATDLLRTRFKLDAEAVNAITQSARTAVPKPAIRSLNRRWDEDEISAESYQE
                     ARLGLEIQAQLRLIEKYRKRLEVSEREWKSINAAPLQDHEIGHIWGIPAGSLAGRKVK
                     HLHQYLHAIQSALQKASAQTVPTTGALDLWKETLAVLGERPVERSIALYDGLERTEEA
                     LVEKLRTFAWGTLGEDLEAKFWLSLVHGASSNAVHSENTRSVFGLQRLLAVLSEIDSS
                     PDALEEELLARTVATPKDVPALTDEAAQPKAEEMGQMQQHVLTSFIGELHNDLQR"
     gene            12794..13249
                     /locus_tag="PK063_08270"
     CDS             12794..13249
                     /locus_tag="PK063_08270"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97083.1"
                     /translation="MYNPPIMQHDHVMIPVRSLARVAGLMLCMLVLPLSIMPVASLFA
                     AGLVEVTELLAHPDHYNHQVVTVSGRVSSFQLATNRDGQPAFGFLLQDTAGTVKVVGL
                     GKADVREGDYVVVEGIFSRLRQAGRAIVYNEIKATSVQSMAKMNPDLVG"
     gene            complement(13246..13722)
                     /locus_tag="PK063_08275"
     CDS             complement(13246..13722)
                     /locus_tag="PK063_08275"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: protein motif:HMM:NF012478.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HMZ97084.1"
                     /translation="MHVTAGDVVSVEYVIRLEDEQVIDTTVGEAPLVYTHGQHEILRG
                     LEAGLEGMAIGAAKRVTVMPVDGYGERHPEGLFEVRRDRVPVEAQRVGAKLETTAPDG
                     RVVFPYVAEIKPEVIVLDLNHPLAGKTLVFDVRVIDIEREGNRVVEEIAPAKKGES"
     gene            complement(13960..14526)
                     /locus_tag="PK063_08280"
     CDS             complement(13960..14526)
                     /locus_tag="PK063_08280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF882 domain-containing protein"
                     /protein_id="HMZ97085.1"
                     /translation="MPSEVLSVSSRRNFLRTVTVGTALFVANLALPAKARASRLPTGR
                     ISLFNLQTEERLSVTFRTESGTYDQSALDDLNYFLRCHHSNETTTMDVQLIEFVTLVQ
                     QKVGGRRDIHIVSAYRSPEYNEQLIRMGTRAARHSYHVSGQAVDVQIPGVPLRTVREV
                     ALRLGCGGVGYYPRGKFVHLDSGPFRHW"
     gene            complement(14837..16249)
                     /locus_tag="PK063_08285"
     CDS             complement(14837..16249)
                     /locus_tag="PK063_08285"
                     /inference="COORDINATES: protein motif:HMM:NF025885.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ97086.1"
                     /translation="MAKHSVVIVGPDQSTVSAAQALIQDEFEVSTAMWTTDTLLPIHE
                     QASPVMLLDIDSPSQPSAEEGLNVLQKLRQTGYSGKVIAYTGRPERSVAVRAVQCGAC
                     DVLAKSLDPVQLLQSIERVARVADLEQEARGAMVVGGPEEFSGMLGMSASINRIFDAI
                     RKVSTSDAPILITGESGTGKELTARAIHARGLRKQGPFIPINCGAIPESLLESELFGY
                     ERGAFTGAVGQKKGKVEFAQGGTLFLDEVGELPNALQVKLLRFLQDHTFERVGGHQAI
                     EMNVRIIAATNVNLKEAIEKGTFRDDLYYRLGVVHINLPPLRERGEDVSLIAMAFLRQ
                     AAAHYNKPLYGFTREALEAMQAYSWPGNVRELSNRIGRAVVMAEGTHITAADLDLPRQ
                     APPQDDGSISLKVNQQRIETDLIMKAFTLSQGNLSRAAQELGISRSTLYRRLRQYGME
                     RSLEARRFPGLSPRASMTEH"
     gene            complement(16360..16752)
                     /locus_tag="PK063_08290"
     CDS             complement(16360..16752)
                     /locus_tag="PK063_08290"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97087.1"
                     /translation="MGQSSTGGNGARSGKRPTVAVIYEDVTSGYRYADWFALHGYQAT
                     MTSAVPHLEHHLQELRPDVIVVGLSSCSTPLQTAVPRLKRTCPQVPIIAMLDRTAQEA
                     NGAVPALAKAFGGDVFMCDSLDPPSTVS"
     gene            complement(17143..>17343)
                     /locus_tag="PK063_08295"
     CDS             complement(17143..>17343)
                     /locus_tag="PK063_08295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="HMZ97088.1"
                     /translation="PHERLSDREYEVLCLIASGQTVSDIAESIHLSVTTISTYRARIL
                     DKMNLKNNAELTRYALQHGLVV"
     assembly_gap    17344..17443
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(17557..20709)
                     /locus_tag="PK063_08300"
     CDS             complement(17557..20709)
                     /locus_tag="PK063_08300"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ97089.1"
                     /translation="MYSLARFSLLEMTECSAVLRQLGEQSRSLQEAASKAVNYLFDTL
                     GDPTTGQRDCVLVRCFKTISYSRLDTEHQQLVREKLGGIAPFPDLRCFTLVASTGAEP
                     DWNRVDRSHRYRVIPMVSADFVKQFPMFSQLLHQFGVSTEFDVRPDGEWLVDLEEKTY
                     NVFYVPDAVGSPYVPVQDGFVGKYGVKSVLCFGGMLPSRDLFAVILFSKTPVPRETAA
                     LCKSLALSLKTSLLAFDEASCTDSGASQQSGSAPEPPASLRHQSRLAVAEQLLRVYED
                     AVRTQSAGIAQAKQALHDRATALQRSEQALHEQTRIVNSVLRSMGDGVVVTDAAGKLV
                     LANPALESIVGFSPGDVPPIEWVDRYEFFHGDTATPFQRDEWPLARALKGEKVDWLEV
                     YMRASQGVPGRWVSINARPIRDDAGLLCGTVVVFHDITWLKRAQDALFESEYRFRSLV
                     EGARDIIFTLSADTTMTSLNQAFETVTNWSRSQWIGEPLATLLHPDDAGFCQDVLQAI
                     LERGTPLTCSMQISTKQGGYVTGEFVGTPQMRQGRVVGVLGIIRDVTERRRIEDALRV
                     SEERLRSIVQSTKDAIVLVNALMKVAFWNKGAEATFGYSAEEIIGQPVTMIIPEQYHE
                     ELERNVQRVRVLERVQSTSKTLELVGRRKQGDEFPLELSVTSWKGKSDLFFTIIMRDI
                     SERRTAEEQLDRLHYHNQVVLNSAGEGIYGVDREGRLTFVNPAAAKMLGWEADAMIGR
                     SLSALVFSPDLAERPFGALSCPIVETIRDGEVREQVDSAFWRKDGTSFPVEYVSTPIS
                     ERGELVGAVVVFKDTTDRKRAEAQLQDSLRRLRKLSGRMEGIREEERGRIARELHDEL
                     GVGLTCLKIDLSRLGGLLGERLVSGDRAKVDEKIRGMKEQVDSTITSVQRIVAELRPG
                     VLDDLGLVAAIEWQCRDFQRRTGITCHCVVSHEDLRVDPEQATAVFRICQEALTNVTR
                     HAQATEVHVRLEEQNVGLLLQVRDNGRGIPQDRLADARSFGLLGMRERAGLLGGDVQI
                     ETLEGNGTTITLQLPREGKG"
     gene            complement(20964..21386)
                     /locus_tag="PK063_08305"
     CDS             complement(20964..21386)
                     /locus_tag="PK063_08305"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012514.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HMZ97090.1"
                     /translation="MAEGGLVRSAGGVVLRQQEVLLIRVSDIKGRPVWSFPKGRLDAG
                     ETPAQAAVREVREETGWSCRIDADLSTTEYWFQREGRRFRKTVVWFKMVPLELTGVPD
                     GEVEEVQWVERTEALRRLTYASDAALLSHALELDPSSR"
     gene            complement(21434..22291)
                     /locus_tag="PK063_08310"
     CDS             complement(21434..22291)
                     /locus_tag="PK063_08310"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012334.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HMZ97091.1"
                     /translation="MQGAIVITGASTGIGAACARYLDGLGFTVWAGVRRKEDGEALAR
                     STSARLRVLLLDVTDSDSITEASRTLTDALPEAGLAGLVNNAGISVAGPLELLPIAEV
                     RTQFEVNVIGALAVTQALLPLLRRARGRIVNISSIAGLAATPFLGAYCSSKFALEAMS
                     DALRLELAPWGIAVALVEPGAIQSQIWQRATMSATRTLGGVAPESLALYAQSLARMQD
                     VMAGAAARAIPAEAVAQVVARALTVPSPRARYLVGKDARFRAVLKWLLPDSAQDRLLT
                     WFLGLSRHA"
     gene            22610..23248
                     /locus_tag="PK063_08315"
     CDS             22610..23248
                     /locus_tag="PK063_08315"
                     /inference="COORDINATES: protein motif:HMM:NF017200.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97092.1"
                     /translation="MMAILVLSLLGYFALLPSTAQASRTLVVPISVATYTDTQVGFPT
                     FVMKWDEGAQPDPLALRWGRSQVPVRGTGMASIQHAFQFAVTRLGASIRPTGTLSLYA
                     TFTGPLSEEGSTAEAALAIGFIALLKGDQLRRDITITGTLEGDGRIGQVDQVAEKTTA
                     AARAGYHVLLVPRGQFYAPRVNRVSLTPESNVLVREVETIEEAYEIMTGKKL"
     gene            complement(23326..>24771)
                     /locus_tag="PK063_08320"
     CDS             complement(23326..>24771)
                     /locus_tag="PK063_08320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAT domain-containing protein"
                     /protein_id="HMZ97093.1"
                     /translation="YLGGLREQEHRNPEALEYTRKATFAAQKVNAPESLYRWQWQTAR
                     LLRAEGKEDESLAAYQRAVTLLKPIHYEYSVGYQGRHHSYYESVAPLFVEYEDVLLRR
                     AAAAKTPEQNDQLLVKVKETIEVSRAAELQDYFQDDCVATVASHRGAGALAPGTAVIY
                     PIAFPDRLELLLETSNGLKQVRVPVAGEKLTKEIRSFRRLIQDSQSQNYLSSAQTLHG
                     WLVAPIQQDLQGAGVHTLVVVADGSLRTIPMGALHDGRHFLVDSLAVAVTPSLALTDM
                     NGAQRRKGSVLSVGLTESVEGQSAPRYAETEVQAIRTMYGGKLLMNKQFSTPTLEEEI
                     KDQGLGIVHVASHTVVGTEARDSFVLAHDGKITMDRLSQLVGLQQYRQQPLDLLTLSS
                     CEIAAEDDRAALGLTGLAVKTGARTALASLWTSDDETTTELVSEFYRQLQDPAISKAV
                     ALQRAQQKILSQRGHTHPSYWAAFLLINNWM"
     assembly_gap    24772..24871
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<24872..25121)
                     /locus_tag="PK063_08325"
     CDS             complement(<24872..25121)
                     /locus_tag="PK063_08325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97094.1"
                     /translation="MPTMRNMVTRRGMKRSHGAAGSAGPRTLSSPLTILSLGVMALSS
                     FTWPASGMALELLGGSSTSSITPAQEMRQGTTQFQQGAF"
     gene            complement(25140..26417)
                     /locus_tag="PK063_08330"
     CDS             complement(25140..26417)
                     /locus_tag="PK063_08330"
                     /inference="COORDINATES: protein motif:HMM:NF017658.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="filamentous hemagglutinin N-terminal
                     domain-containing protein"
                     /protein_id="HMZ97095.1"
                     /translation="MLCRPAGLPLLVRGYLAFLMLLGSTASIAYGQATNIVATPGGPG
                     GLGTTLNTAGNTTNITGGTRPGGGPNLFHSFNQFSVGAGDVASFVNPGGVSNVISRVI
                     GGSPSNINGTVQALNANLFFLNPSGIIFGPSAHLNVSGSAYFSTAQQLRLSDGGIFTA
                     STSLLAFDSTLSASSPVAFGFLGQGPYGSIVLTSSSTVLQTGAVLGLMGGGIQINGSK
                     ISAQRVMLGSTSSAGEMSTQPFVGNPFSGAAGNGQVQALPGTLIVAGGGGVIPASIDV
                     SPNVTVPTGAQVNTTSNSVTQRVTQIQVVGVNLGGLPPLPTANAANVNPTNPVEPVAF
                     LNRAAMVLPQEAPAPPAPLLTSRCAARKDGTFSSLVQASRDVTPSQPGRSLAAPVVLE
                     EIAGDLEPGAPAAPSAHIHGQTIAQLMESWQGC"
     gene            complement(26698..>27870)
                     /locus_tag="PK063_08335"
     CDS             complement(26698..>27870)
                     /locus_tag="PK063_08335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ShlB/FhaC/HecB family hemolysin
                     secretion/activation protein"
                     /protein_id="HMZ97096.1"
                     /translation="LQVEALQERLRVMQANPRIERINAELLPGATIGENTLNVKVKEA
                     NPLKAWLEFNNYQSPVVGAEQGFITLAHQNLLGFGDTLSLQYGRSAGVNPMLNFKYEI
                     PVGPRDTTVALQYRRFDFGVEESPFDSLDIKNKAQIFGLSVRHPVIRKADQELAFSLT
                     GEHARNESTLGGNPFELITGAPNGRFRVTALRFGQEYAQRSAEQVISLLSRFSVGIGA
                     MGATANADPNLPDARFFSWLGEAQWIRQLPFWRTQLVSRGVVQLSNDHLFPLEQIAVG
                     GRYSVRGYREFTLIRDNAAMASIEARVPVYTTKAGVDSVFLAPFFDFGHGWQTTAQTP
                     GTPPKTLASLGAGVIWNFWRGSHFELYYGKQLKRYDTDRNNLQDHGIHLQLVVEAF"
     assembly_gap    27871..27970
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<27971..28336)
                     /locus_tag="PK063_08340"
     CDS             complement(<27971..28336)
                     /locus_tag="PK063_08340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97097.1"
                     /translation="MACVKKSVGQASGIYGAADARLDASGRSSNRGDVLRRWRGTVAG
                     VAAVLLLGALVVPAHSQTGSQLGPLPPKPPQLPVVPPPAQPPALDLPTPTPPGALDQA
                     AKGPKIMVKDIRLVGNTAFT"
     gene            complement(28759..30186)
                     /locus_tag="PK063_08345"
     CDS             complement(28759..30186)
                     /locus_tag="PK063_08345"
                     /inference="COORDINATES: protein motif:HMM:NF009709.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophanase"
                     /protein_id="HMZ97098.1"
                     /translation="MNFPFEPFRIKVVEPVKRTTREERDRLLREAGYNLFHVPAESVA
                     IDLLTDSGTSAMSDSQWAGMMLGDESYAGSKNYHHFETVVRGLFGYRYVIPTHQGRAA
                     EHVLFSTVLKPGMCVPNNIHFDTTRANVEHQEAEAKDLVIKEAYDPHCELPFKGNMDV
                     ARLEETIKRVGPSQIPFVMITITNNSAGGQPVSMANIRATRQVLNRYGIPLFFDACRF
                     AENCFFIREREPGYADRPIRDIARELFRLGDGCLMSAKKDGLVNIGGFLALNDERWAQ
                     AVTNMLILVEGFPTYGGLAGRDLEAMARGLEEVLDEEYLRYRIGQVQALGALLEEGGV
                     PIVKPTGGHAVYVNAKEFLPHLQQSQFPAQALAVALYRDYGVRTVEIGTVMFGKRDPA
                     TEETIYPALELVRLAIPRRVYTSQHLSFVAEALVDLYQRRHSIGGLVMTYEAPRLRHF
                     TARFEEETLAEMLWPGAGFAAAPLS"
     gene            complement(30161..31144)
                     /locus_tag="PK063_08350"
     CDS             complement(30161..31144)
                     /locus_tag="PK063_08350"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HMZ97099.1"
                     /translation="MMEIARYFDAVKDRYDLSSDYALAEKLGIAQPEANLMRRGLKIP
                     KPELCIKMAKLLDKNPVELLLIAQKDKAPKQAKEYWTLALTAVDVMLHVPKRPRYLPK
                     KVEAIGRELKQLEAQTLTYEGAAANAEAVRLMETAEQSVDAMMERWNIWKKGEALYPN
                     YLLANQAAARRHVRIRRLLILTQEQMQHDATVADAIQVMDDQRRAGVKVFYAFREALV
                     HSPAFQRLEEDFRKYGAAEDMNTAMFDREILIFSQTYGSVPLGMVGTPTPITMINRLQ
                     ISWKPEMIRELDPAPLFDMTRYVFDYQGSGPFHEQLAYFRRSIRELPIRAV"
     assembly_gap    31200..31299
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<31300..33047)
                     /locus_tag="PK063_08355"
     CDS             complement(<31300..33047)
                     /locus_tag="PK063_08355"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012656.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HMZ97100.1"
                     /translation="MANKDRMFTGSLAVAEAARDTRLYSGFLSGLFEGNVRRHLYSRA
                     SLPARSGAASEFLDRLRHLLIEKVDPETIDREGLIGEDVFAALREIGAFGIKIPRRYG
                     GLDFTQSEYHEAATLLGSHDAATTVLLSAHNSIGAAEPVKLVGNSEQQQRLLPRLARG
                     EVSGFALTEKGAGCDIWDLKTYAIPVHEQGLLVGYRLTGDKLYTTNAPQGHQAFLASW
                     LVVIAQIVDSPQDIHRAKEERRFGAFVVDTHTRGCSCTRLSFMGVRGIYNGQVHLREV
                     WVPVADRLGAEGEGLRRALESLTVGRLTLPAACLGNLKQCLWLARLRAQQRKQYDRPI
                     GEHTDIGAKIVLMASRVLALEAIVKITGIWADTKQDVRLESAAAKILATEWLLESLLD
                     LFRIYGGRAFETPDSLRLHGDLPAPIERMIRDALINVIWEGSNGILTLWIGREGLSQY
                     FTHGQAFLDCHIADMVRATPFFVNTAARSFGGLTVYEQDSEAGSFDPLWERFVARKSR
                     ELARTTLWVAARDRQGLARKQRLMTRLVSAAMHLFAVETALWYKSRQEQRGKPHLDQL
                     VSYFCSRTSAAFNPEP"
     gene            complement(33070..34290)
                     /locus_tag="PK063_08360"
     CDS             complement(33070..34290)
                     /locus_tag="PK063_08360"
                     /inference="COORDINATES: protein motif:HMM:NF013862.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HMZ97101.1"
                     /translation="MASAFGKRALALGGGGFTGYLFEIGALTALDDLFEDGVSMNDLD
                     LYVGVSAGAAAVSLIANGVKPRDILETNLSGTRPYYFDHRNVFSPAIGEGLKTFWRVT
                     RQLVPLVKYYVRHYGEMTLIDLLDKAQDALPSGIYTLEPFALYLAGLYKTKGLSNSFA
                     GLSKELYIPAIDLETGENVLFGEEGWQEVPISRAVTASSAVPIYFCPVRIQGRDYIDA
                     GIGRMAFFEVAVHKKVDFMIMINPMARPLQRRLPVDVPDHGSSVGRLRDRGFLSIGEQ
                     ASRINFDARFSQALERFQHEYPAKEVLVISPVEEDALLFERSFLSYRDRIHLLRAGYG
                     SVMTLVRDQFDHVSAQLASYGMTISRARFEDRAVQRLARLNHVAWTSAPRVVPNAATA
                     ARIGGIGAAWRKAR"
     gene            complement(34327..35115)
                     /locus_tag="PK063_08365"
     CDS             complement(34327..35115)
                     /locus_tag="PK063_08365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="HMZ97102.1"
                     /translation="MTTTAGSMLACHRDGAVATVTIHHPPANTLTPELLGELSQAFEM
                     FATDEAIKVVVLTGTGRFFIAGADIRLLAAIASSQEGASIARQGQAILNRIESLEKPV
                     IAAINGVCLGGGMELALCCHIRLVAEGSRLGQPEINLGIMPGFGGTQRLPRIVGQSKA
                     LELILTGDPISAQEAKALGLVSAVFPPEDLLHQAHSLARKMASKSLPALRASLRAIRS
                     GADMSLPEGLALEAVLFGGLCETEDKREGLAAFLEKRQPRFIDR"
     gene            complement(35123..36370)
                     /locus_tag="PK063_08370"
     CDS             complement(35123..36370)
                     /locus_tag="PK063_08370"
                     /inference="COORDINATES: protein motif:HMM:NF014757.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-CoA dehydrogenase"
                     /protein_id="HMZ97103.1"
                     /translation="MYIYKVGVVGAGTMGAQIAEVVSFAGLPVVLADREEALARRGVE
                     SVRAIYQARVAKGKMTPEQLEEKMLLVTASPNLERLHDADLVIEAVSEDLLLKQRVFQ
                     ELDRICSRSAILASNTSALSISAIGSATKRPDKVIGLHFFNPAYAMPLVEVIPGLGTD
                     PQTVDDVVGFSESLRKQPVIVKECAGFLVNRLLSPYLNEAVWCLQDGDVSIKEIDQDM
                     VSFGMPVGPFTLLDTVGLDIALDVARILHRSYGPRMAPAPLLEAFVKAGRMGLKTGKG
                     LYDYGAAEEGGADQHLERLRAQARQLTGRSSMKWSPLRPLVAMVNEAVIALQEGVASA
                     RDIDFAMAAGTGFPSDKIGPLHLADQLGIDRVLQELEELQDRVGPRFWPAPMLRRLVD
                     AGFTGQGAGRGFFSYEPTIARMR"
     gene            complement(36445..37635)
                     /locus_tag="PK063_08375"
     CDS             complement(36445..37635)
                     /locus_tag="PK063_08375"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006635 - fatty acid beta-oxidation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HMZ97104.1"
                     /translation="MREVVIAAAARTPIGNFGGALKDLTPHKMGELAVREVMARAELD
                     PGLIDEVIIGSVGHTSDAYNVARVIALMAGLPVRTPAYSVQRNCSSGLQPFVNAYQNI
                     QSEDADVQVVGGVESMSRAPFVSRDMRWGKRLRHAEFIDSIWEGLTDAFCGQLMGLTA
                     ENLAEEFNISHEEQDHFAVESHRRAFKAIREGRLKDEVFPVMVQKTVAGREVPPVAVV
                     QDEGPNVGLTEQQLALYPPLFKEGGTVTAGNSCPLNDGAAAAIVMSGARARDLNHRPL
                     GRIKSYAFIGVEPTRMGIGPAEALPLALKRAGITLTDLNLIEVNEAFAAQYLAVERVL
                     ELKRDIVNVNGGAIALGHPVGMTGTRLVMTLLYEMKRRGAALGAVAMCVGGGQGAAMV
                     LEQI"
     gene            complement(37655..39370)
                     /locus_tag="PK063_08380"
     CDS             complement(37655..39370)
                     /locus_tag="PK063_08380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="HMZ97105.1"
                     /translation="MPRPWISRYDPGVSATCDYPEWTVPDLLRRSASRFPESPALFFY
                     GTRISFQELNELSTRFALGLRRLGVETGDRVALMLPNIPQAVIAYYGVLKAGAVVTPT
                     NPLYVEREIEGQLHDAGSETIVALDLFYPRLQAIRERTGLLHRIILTSLRDFLPPLKR
                     WLYPIKARWAKRWISVEKYPPVYDFCALLDRGARERDVDTEPLPTLEPGALAQIQYTG
                     GTTGIPKGVMLTHRNVVVNTMQGRFWCANFREGKEVFLGAVPLFHCYGLNTCQNLAIA
                     TGSQIILLPRFHADEAVKAIQQHRVTIMSGVPMMFSMMTDSPNVRRYDLHSIRVCLCG
                     ASPLPAEVQDAFERLSGVKISEGYGLTEAGPTTHCNPIERDHPPGSMGLPFPDTEARI
                     VDLETGLTDLPTGAAGELIVRGPQVMRGYWQKEADTQAVLRDGWLHTGDIVRRDEQGF
                     FFFLDRKKDVIKPWGETVYPREVEEILFQHPAVHEVVVVGMPDRHYGEAVKAFVVPVE
                     ESSVTERELIDHCRKSLARFKVPVAVEFRSELPRTIIGKVLRRALRDEAEVPVGTAQA
                     PRKAV"
     gene            complement(39403..40161)
                     /locus_tag="PK063_08385"
     CDS             complement(39403..40161)
                     /locus_tag="PK063_08385"
                     /inference="COORDINATES: protein motif:HMM:NF025871.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing redox enzyme family protein"
                     /protein_id="HMZ97106.1"
                     /translation="MSFYEQVRSDVLRHGAINNSYLDRFLAGDVSDKEFREFAVEFYN
                     FSRFFPRILAAQLVNTEDEAVADELTKVLYSELGDGSVKHRHELLYRNFLRSLGIDIH
                     VAMTTPMRPSTKAYIEGMERLYGSGNHAMALGASFGLENMAITMWDHLIPGLTRLRAE
                     RYADMDMTYFVFHRELESEHERAMQHAIVAVDGDSHAPHARMSDKEKDDFRLGMNAVL
                     DYLEGFWMGLERKPAGVAQSRSRPVHGLESELRG"
     gene            40376..40975
                     /locus_tag="PK063_08390"
     CDS             40376..40975
                     /locus_tag="PK063_08390"
                     /inference="COORDINATES: protein motif:HMM:NF025050.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HMZ97107.1"
                     /translation="MKEAIGVDHITLCVKNLSATKYLFTHILGFDVIWSAQDVGSEKS
                     SMDTVVVQRGAAKIALMQGRNKERKSQICEFVETYGEGVQHIALEVDDIEAVCREWEH
                     HGVRFSGDIKDGRDGFGPLRQRFTYPLFPGCGLFLELTQRQHGTEESKTFVRATVESL
                     YRDIERDQIKGVARTIIDYETLPLPFEEEVEAASLRHAS"
BASE COUNT         8543 a        12747 c        11015 g         8290 t
ORIGIN      
        1 gcttcgatcg cctcggtcac tttcgcatgg gtcgaatggc caccgagagg gaacccgatc
       61 ggaatgccca cttgcacggc ggttccggcc acggccgcaa ccgcctcatc gacataacag
      121 ggcggcacaa aaatcacgac aaatccctgc tccttcgcct cggcacacag ccgcaagacg
      181 tcggcctttg tcgcctcggg acgcaatacc gtgtgatcca gcagagcagg taaattctca
      241 ttccacgaca caagtcccat gcgcgattcc tttcagatga tgaatgttga tggatgtaat
      301 agaccgtcac gaggcgatgc ggcgtggagt aaggcaccaa taagatcacg cgccgtgagt
      361 caccaggctt cccctggccc gcttgcggaa cggctgcttc tgatactttt ccacggcgag
      421 attatgttcg gccagggttg aggagaactg atgggtgcca tcgttgcgcg agacgaaata
      481 gagataggac gcctgcgccg gaaacagtgc tgcacgaagc gagtgagctc ctggactggc
      541 gatcgggccg ggcggaagtc cctgcacacg atacgtattg taggggctca tgacggacag
      601 gtcgcgttta tgaatattgc cgtcgaacgc cgggagccca tagatgaccg tcggatcgct
      661 ctggagggga atcttctttc gcaaccggtt gtgaaacacc gccgcaatca attcccgctc
      721 ttccttggag ccggtctctt tttcgatgac tgatgccagc gtcaagactt gatggagcga
      781 caacttcatg cgcgcggcct gttcctgcaa gtcggcgctc catacgcgat ggagcccgtc
      841 caccatggcc ttgatgacat cacgggcctt ggcttggcga ggaaaggaat aggtctccgg
      901 aaacaagtag ccttccagcg agtccgcttc aatccctagc gtcgcaatga acgtgcgatc
      961 gcgcaccagc ttcgagaatt ccttcgcatc cgtcacctgc tgtcccgcca gcacctcggc
     1021 gatttgcgca agattgtatc cttcggggat cgtgaccgga tgcaatacga cccggcccgc
     1081 caacagctta ctcagaatgt cctgaggcga catgccgcca tcgagttcgt attcgccggg
     1141 gcgaattttg cgatcactgt cgtgcgaccg gccaagcagg agaaacgccc agcggctgcg
     1201 aatcagctgc tcgctcttca acatgcccgc aacctgctga aaggtactgc cgtcaggaat
     1261 cgtgacgatc ttggagggtg gcttaggaag cccgctggcg acgggacttt gagcccagcg
     1321 caggaccaga tagcccgaga gggccaagag tatcaccatc gctagaacca gtcccgcaat
     1381 caatcgcttc tgcatcatcg actcgtggtt cgtcaaaaga ccagggatcg tcttcgtggg
     1441 aattgcttat ggcctgctct tggctcgtcg acggcttctc caaactcgcg aggtaactct
     1501 ggaggagaat cgcggcagcg atgcgatcga cgatgccttt ccgtttgcgg cggccgacat
     1561 cggcggcgat caataagtcc tccgccgcac aggtcgtcat ccgttcgtcc caggttacca
     1621 ccggaaccga caaggccggt tccagcagtt ggatgaactc ctcgacgact tttgcggcgg
     1681 ggccactttc cccgtccaat cgaagcggta agccgacgag cacccggccg acctcgtgct
     1741 cgcgcaccaa ctcctgaata tgtcgaatat cggcctcggg attgcgtcga tgaaacgttt
     1801 ccaacggctg ggcggtccac ccgagctcat cgctcagggc aaagccgata cgtttggatc
     1861 cgtgatcgat cgcaagaatc cgctggcctt tcatcagtct acccttccaa ggccttttgg
     1921 accaacccaa aaactttttc gagcgccggt cccagccctt cgggattttt tccgccggct
     1981 tgcgccatct cagggcgacc accgcctgtc ccgccgactt cggtcgccat cgccttgatc
     2041 aattcacccg ccttcaaacg gccgaccaga tccttcgtca ccaccaccag caacgagacc
     2101 ttgccgtcgt tcgccgcgcc caaagcgaca acaccgcttc ggagcttgtc ccgtagttga
     2161 tcggcgagcg cccgcatgcc gtttacatcg aggccatccg tacgttgcgc gtgcacctgg
     2221 acgcccttga tctctcgtgc ctgcgcgtca ccggacgatg tgctcgccat tttcagcttc
     2281 acgtctgcaa gttcgcgttc cttgtccttc agctgttcgc tcaacttccg ggtgcgcgcc
     2341 acaacctccg tcggcgcgac tttcagaagt tcagacatct ctcgcacatc cgcttccagg
     2401 cgcttgaggg aatccaaggc accactcccc gtcaaacact cgatgcggcg caccccggcg
     2461 gctactcccg attcagagac gatccggaac aatccgattt cccccgtacg cccacaatga
     2521 gtgcccccgc acaattcctt gctgaaggtg tcgatctgga ccactcgcac ccgatcgcca
     2581 tacttgtccc caaagaaggc caatgccccg cccgccacgg catcctgcac gcccatcaca
     2641 tcggtttgca ccggctgatc aaggcggacc tgctcattaa cgatcgattc gatctcgtcg
     2701 atgtcacggg acgacatggg ccggaaatgg gcaaagtcga accgcagacg attcggtgcc
     2761 acgagcgagc cgtactgttt gacgtgcggc ccaagtagat cgcgcaacgc ggcatgcact
     2821 aaatgggtag cggtatggtt acgcgccgca tctttcctgg tccgaggatt caccgaaagc
     2881 tgcagccgtt cgccttcacg aatagaaccg gatgtcacca cgcccttatg gacaatcaac
     2941 gtcggcactg gtctggtggt ctcgcgaatc tccacgcggc cgtcggtccc gcttaacaca
     3001 ccttgatcgc cggcctggcc gccgccttct gcataaaatg gcgtgacgtc gagcacgatc
     3061 tcgatttcgt cgccttcccg ggcttccttg atcaagcgat cactctgaag gagcgcctgc
     3121 accacacctt cggaatccaa gcggtcatag ccgacaaatg cggtggttcc gacacgcgcc
     3181 gccacgtcgc tcagggccgg cctcgccgtt tcgctctcga agccccccgt ttttctggcg
     3241 cgcgtccgct gctcttcgat ggccgcttca aagccggttt cgtcaagggt gatcccctgt
     3301 tcacggcagg cttccgcgat gagatccatc ggaaacccgt acgtgtcgta gagtttgaaa
     3361 atttccgtcc cctgcaacac atgctgcccc gacgtcttca ccttcgacag catgtcgttc
     3421 aggatcggca acccttgatc cagtgtggcg ataaaccgct cctcctcacc gcgcgtcgct
     3481 tcagccaccg tcccggccgc cggccgcaat tcgtgatagg cctcgcccat ttggtccacg
     3541 accgtcgccg tcaattcgtg caggaacggc tcggtgatac cgagcaaccg tccgtgacgg
     3601 gccgctcgcc gaagaattcg ccgaagcaca tagccccgcc cttcattcga cggcaggaca
     3661 ccgtcagcca tcaggaacgt aatggctcga aggtggtcgg caatgacccg catggaccga
     3721 tccgactgct ccaccgctcc gtactcagca ccggctcgcc gtccaatcgc ggccagcaat
     3781 ggcgcgaaca aatcactgtc gtaattgctg agccggccct gcgcgaccgc cgtgagtcgc
     3841 tccagtccca tgccggtgtc gatgctcggc tttggaagcg gattgagcgt cccggcgcta
     3901 tcgcgattga attgcatgaa caccaggttc cagatctcaa tgacccggtc gccttcaccg
     3961 ttcggcgtat catcgcccgg caccgacggc ccctgatcga agtgcagttc cgagcaaggc
     4021 ccgcagggac ccgtgtcggc catctgccag aaattgtcct tctcgccaca acgcacgata
     4081 cggctcgggg acacgccgat cttccgccac agccgatcgg cttcgtcgtc ttcgcgaaag
     4141 atcgtgatcc acatccggtc tttcgacagc ccgaccaccg agatcagaaa ttcccagccg
     4201 aagcggatgg cgtcttcctt gaaataatcg ccgaaggaaa agttgccgag catttcgaag
     4261 aacgtatgat gccgcctggt gtagccgaca ttttcaaggt cattgtgctt gccgccggca
     4321 cgcagacact tctgcacggt cacggcccgc tgataggcgc gcgtttcttc acccaggaac
     4381 acccgtttga attgattcat cccggcgttc gtaaacagca acgtgggatc cgcctgtgga
     4441 atcaacggcg cgctcggcac cgctcgatgg ccctgctgct caaagtaccg gatgaaggct
     4501 cgccgcagat cgtttacact ttggctcata actcgtctaa ccccgtctcc aagtcgactt
     4561 gcgtgacttg ctgaatggtg tcgtcatcaa acccgcgttg ccgcaaaaat ctcacccact
     4621 gtagtggacg catcctcgtc gttcgtcctt ctaacgcctg gcacgccaat tcctgttcgg
     4681 aaaccgaccg gtaagcactg cacaaggccc gctccgccac cgtatcttcg aagcctcgac
     4741 gaaggagttc cagcttcagt cgttcacgtc ccatcgggcg tcgcgagagc cgggcttccg
     4801 cccaccgggt ggcataggct tgatcgtcga gatacccgcg ccgctgtaac tcacggacaa
     4861 ccgcgtgccc ctgcacccgg ctcgcccctt tttcttgaac gtagtgctgg acctgagagg
     4921 ctgtccgctc agcacggcca aggtaccgga tcgccattgt caggaaatcc atcggcgact
     4981 ccctgcgtcg tggtacacca cgtccagccg acatcctgct gcctatgatg tcactctcgc
     5041 actgtggccg cgcttctcgt cctggcgaat ctcaaccttg cgctcgggtt tctcttcttt
     5101 tgcctctttg gcctcggctt tcttctcggc cccgcgcaaa ggcagcccgg ctagttcgcg
     5161 caccttgcct tcgatctcct tggcgatggc cgggttggtc ttgagaaagt cgcggacggc
     5221 ttcacgcccc tggcccaatc gctcgccctt ataggagtac caggcgccgg ccttctccac
     5281 cacgcgcttc tcgactccca tatcgacaat ctcgcccgat ttggaaattc cctcggcgaa
     5341 catgatgtcg aattccgcct gtctgaacgg cggggccatc ttgttcttga ccaccttgac
     5401 gcggacgcgg cttccggtga catcctgccc atccttgatc gactcaatcc gacgaatgtc
     5461 gaggcgcacg gacgaataaa acttcaaggc gttgccgccc gtcgtggttt ccggattgcc
     5521 gaacatcaca ccgattttca tgcggatctg gttaatgaag atcagggtcg tctgcgattt
     5581 ggcgatggca gccgtcagtt tacgcaaggc ctgggacatc agtcgtgcct gcaaccccat
     5641 atgggcatca cccatttcgc cttcgatctc agctcgaggc accagcgccg cgacggagtc
     5701 cacgacaatc acgtcaatgg cgccgctgcg gacgagggtc tccgcaatct ccagcgcctg
     5761 ctcgccggta tccggctgcg acacgagcaa gtcgtcggtg tgtacgccca acttcttggc
     5821 ataggtcaaa tccagcgcat gttcggcgtc gatgaaggcc gctacgccac ccgccttctg
     5881 tgcctcggcg atcgcatgca acgtcagggt ggttttaccg gacgactccg gtccaaaaat
     5941 ctcgatgacg cgcccacgag ggaatccccc tacgccgagc gcaatatcca atcccaagga
     6001 tccgctcgag atcgccggta cgtcggccgg tcgatcatcg gtccccagct tcatcaccgc
     6061 gcccttgccg tattgttttt caatctgagc cagggccagg tccaacgcgc gtttcttttc
     6121 atctttttca gacattcata actccttctc gcgacatgac tcgtgaagtg tgcctgtctc
     6181 gcatgccgtg ggagacaacg caccagccgg ccatgagttg accacgcgcc agactcagac
     6241 caggaacgca gacagaacag cggattatac cggacttaga aggaagaagc ctagcccgca
     6301 cgggcctgcg atccatccaa tctcgtcaat caagacggga tggagcccct tcgtgaatct
     6361 cgcgaaacca tgcatcgaaa tcccctgatg ctccatacct gcttccggca tcgacgtcaa
     6421 aaaacccgca gccttccgtc atagctgcca cgtctccgac gtgagagggt attggtcttc
     6481 gcccgccgtg catcgcgagt ccttcctggc gacctgacgc gtaagtatat gaaaatgcgt
     6541 ttgagactga agggagctgg ccaaagagcg gacggctaaa gtcatagcgc ggacgcgccg
     6601 acattcttgg tgagggacaa tgcgcttggc accaagcttg ctcctacctg gagtattcgt
     6661 tcacctctta cggatgcagg aggcccccat gccacagcaa cacatggacg atcattcagg
     6721 acaatctgcg gttcaattgc atgtgcccgc cgctcgcgcg ccacgcgact tgacctatga
     6781 cgaaaaaaaa gccgccgagg cggcctttcg tggcgaaccg ttcaatcccg cctggtctgc
     6841 cgcggcagca gtcgtgtatg aagggatcgt ctcagcgatg tgtcgcatgc aggtcgcctc
     6901 actgactgat atggaggccg tttctgtcgc tgaggaatgt ctcacgcgat aaatgactcg
     6961 cgcacgaggt catgcggcca gacgtgtcgc tcaggctgcc gaagctgcca gcggacattc
     7021 ccacagcttc gaatagaccg gcccggcggg atgcaattcg cttctcatca tgacgagcgc
     7081 cttgatcggc aggacaccga tcgtcaccgg ttgatccaac gctccgcttt gagccaggac
     7141 ctgtccaacc tgtcgttccc cttcttttat acgtgctagc gtcagatgcg gactgaacgg
     7201 ccgtacctcc gcagccaaac cggcctcccg acatacctcc tccaccgccc gatatagtac
     7261 ctgcaagcgc tgcccgtggc ttccctgctc ccaactttcc agcggtccag cccacagaac
     7321 tctcggctgt tggattcgag ggaacgttcc gagccgggaa aagggcactt caatcatgtg
     7381 atgattggcg actacttcgg aaaccactgc atgaagggat tcgatcacct cttgcggcgt
     7441 ctcgcccaga aacctcactg tcagatgcat ggaggctggt tgtacccaac tgacacgcgc
     7501 ctgccgtccg accgctggct ccagccgtcg cttgagatcc tgctggataa ccgatagggc
     7561 cgcgcgaaaa tccggaggca attcgacggc cagaaacgcc ctgatcatcc gccacctttc
     7621 gtgatcaacc agcgacggag aacatccagc gcggcctgcg aggagcgctg cttgatgacg
     7681 ctccggtcgc cgccatgaaa acggaattcc ttcgtcaggt tctcgcccgg tcccccgtcg
     7741 agccccacat agacaagtcc caccggcttg ctcttcgtgg cgcctcccgg cccggcaatg
     7801 cccgtgacac tcagcccaac tgagacgccg cttcgttcac gaatgcctcg cgccatggcg
     7861 gccgccactt cggcactgac cgcgccatgc cggtcgagga gatcctgaga gacgcccaac
     7921 aattccacct tcgcgcgatt gctgtaactc acaacgcccc gatccacgta ggctgacgat
     7981 ccgggtatct gagtcagccg atggccgatc aatccgccgg tgcacgattc ggccaaggcc
     8041 agtgtcaggt gttgatcggt gagtaatcgc ccgaccaccg tttccatcgt ctcgtccgcc
     8101 tccccataca taatgtctcc gagccgggtc ttcgcgtctt caaacaggcg gtcgatcgtc
     8161 acaggccccg actccttctc cggccctgtg agcgacacca tcacttccat gggggaagca
     8221 taaataccga gctgaatcgc cgtcccgtcc ggaagcaatc cctccaatcg ctgatccaca
     8281 atggattccg gcacgccgga ggtgtgcagc acccgccgaa tgacgggagt ggcagggatt
     8341 cccttgtgct taccgatcca ggcctgcagg cgaggcagga ctccgtcttg gatcatcggc
     8401 tccatctcac gtggcactcc gggtaaggct gcaaagaacg tgtctttcca gatcaaggcg
     8461 aaccccggcg ccgtaccaac cggattggtc agcacttccc cgcctgcagg aatcatcgcc
     8521 tgtcgcaact gcgccttcgt cggcgttcgc ccccactcgg ccaaacgagc gatcatccca
     8581 tcaagtgctg tctttcgtcg gctcaggcgt tgtcccgtcg cctgcgcaac cgcctcacgc
     8641 gtgaggtcgt cgatcgtcgg tcccaatcca cccgtgatga tcaccacgcg gacgcgccgg
     8701 gccgccgttt tgagcacccc cacgatatcg gacaactcat cgccgacaat cgacttgtat
     8761 cgaagctcca caccacacgt cgccagatga tcagcgataa acagggagtt tgtatccatt
     8821 ctgccaccga gcaataactc agacccgatg gcgatggttt cagccgtcca ggctttggac
     8881 ttgttcatgc ggaatcaacc tttatagttt gaaaggcgtg aaggaatgtt cacgttattc
     8941 gatatgggca aagtccaatt cgaaggttac ctgcccgccg ctggatggaa acacgctcaa
     9001 ggttgtcttc gcatgcggat cgagatcggc gtagggaaat tgggcaatca ccttcgcgcg
     9061 ataggcaggc tgttggggcc agacggatgt ccgttcgccc cgtgcatcaa atcgcaccga
     9121 ggagggtttg accgtccgcc ctgcctgctc caacacaatg taactgtcgg cggcgaagtt
     9181 cacgcggtcg ccgaacagca cgacattcac cagaaggttg ccgttcgcca tcacctgcgc
     9241 aacgtcctga tcggtgggag acagcgcccg caacgacaag tggttggcca tgaccagcag
     9301 actgcccagc ttggtcatga tgaatccgtg cggagtcaga tcctctttgg cgccaaacca
     9361 ttcatgcagc tgatccggag acgcaccctt ggcagcggcc gttttccccc gttccatcgt
     9421 ggcttgaatt tgttcgggag tcggctgcac ttcgatggcg agcgacagag ccggggggcc
     9481 cgtccctgcg acgacgaaca ggtagagcgc gagtttgaaa ccggcacacc gtcgccgaat
     9541 ggtacgcatg atgaggaggc agtaccagat cgataggggc ctgtcaattc gctgccgccg
     9601 caccccgcca tcggttgaca gcctaggaga cgaaatgcta aagagctaat tcttattctt
     9661 tcacattatc aagaagttgc ctggagggtt cctcatgtcc agccccgaac aagcgccccg
     9721 ccgtcagtac gtgaatttca ccttctacaa agttgatccg gcatggcgtc ggcttcctga
     9781 agatgagcgc acgcgcggaa aacaggagtt cctgcgtgcc gtggaggaat accagggaaa
     9841 agtgctcgtg atcgcgtaca cgagcgtcgg tattcgcggc gactgcgacc tcatgctttg
     9901 gcgtatcagc tatgaactcg aattgttcca ggaaatgagc accaagatcc tggcgtccgg
     9961 attggggaag tacattctca atccgtactc gtacctcgca atcaccaaac gctccattta
    10021 tgtcgacaat cacacccacg agaatcagga aagcaaacgg ctgacggttg tgccgggcaa
    10081 ggcgaagtac atcttcgtgt atccgttcgt gaagactcgc gaatggttcc tgctcaccaa
    10141 ggccgcgcga cagggcatga tggacgaaca cattgaagtc ggccatcgct tcccctcggt
    10201 caaactgaat accacgtact ccttcggtct cgacgaccag gaatgggttg tggcgtttga
    10261 gagcgacaag ccggaagatt tcctggatct cgtcatggca ctccgggaaa cggaaggcag
    10321 ccggtatacc ctacgcgaca caccgatctt cacctgcatc cgcaagagcc tgaaggaagc
    10381 cttagacacg ctcggcggtt aaaatcgatt gacactccct gacggttcgc acggccttcg
    10441 atccagttga tcgagggccg tgtacgttct accccactta tccattaagc cactgcacct
    10501 ccgcagatcc atgtcagttg aagctcaaac tcacccggcc tccgattacc gcgcagccgt
    10561 gtactcagcc attctccccg gactcggtca cctgctccgc ggacggcata aagccgcgat
    10621 gttttttggc ttcatcacga ttctcctcat catccttagt ctgggcctgg gacgcgtatc
    10681 gggtcgagcg gcggaagtct tcttcttcat gctcctcgcc cttccctggt gggcactgca
    10741 gagttacgat gccgcactcg gaccggccgc ctcgggctcg gacctcgtgc gaaccggccg
    10801 cctggcatgg gcagaggggc atgatatccg gttccttggc ctcctctttc tggtcagcgc
    10861 cgccaacgat gcgattatca tcgccaagaa ccccgactat ctcttgccat ttttctgtac
    10921 aaagttggac ggagctgccg gcttcgtcac caaggccctt tccccatttc tccatacctg
    10981 ggtggggtac ggctttctgc gcatcaagaa gtggtcactc ctggtgtatt tggtctatgc
    11041 ggcctacgga accaccaatg ccctcgtcaa tttaacctgt ttcggaccgg gtcgaattcg
    11101 gaacactctg ctgatcgccc tcattgcctt taccagctac atcctctggc gacgacggat
    11161 gttccagcgc tgaccagatc cgctcggcag ttgaagatcg cattttgaca ctcggctcta
    11221 ggctgtgtta cctgtaatag cgataccgtt ccccatcctc agatggagca gctcctatgg
    11281 ccgaaaacaa tgcggtctat gcgattcgcc accctgacgg ttctgtgacc ctgtatatcg
    11341 acgaagaata tgccatcgat cggggcgtcg accccgccaa gctggtgcgg gtcgaaatcc
    11401 cgcgcgaatt gttcgtcagc ggcagcatcc aacacattcg ggaatacgtc gcggtctacc
    11461 ttgaaaatag ccatcagggc acggcctgag cgaacctttt acctcgcaga gaggccacac
    11521 catgtccgcg ttactcacct cggaacttat cgcctccacc atcgaacaag caccgattca
    11581 gggcagggtc atgctcaagc tgctgctctt gcagcatttt gacatcacgc ccgaggaaat
    11641 cagctatatc gccgccgacc gaccggatcc tcgctgcgtg gccggctcca aaccgatcca
    11701 ccagatggtc aagcaggatg cgttgcggga tgtgaccaat cgcagagatg agtatcgccg
    11761 ccgagttcgt ctgcgtcggg agcgtctctg gctgcagatg gaagccatga agggcatgat
    11821 cgccctggct gaaggcatga ttcgggcagc gaccgatctg ctgcgcacgc gtttcaagct
    11881 cgacgctgaa gccgtgaacg ccattacgca aagcgcccgc acggcagtcc ctaagccggc
    11941 gattcgatcg ttgaaccgca ggtgggacga ggatgagatc tctgctgagt cctatcagga
    12001 ggccaggctt ggtctggaaa ttcaggctca actccgcttg attgagaagt acaggaagcg
    12061 cctggaagtc tcggagcggg aatggaaatc gatcaacgcc gctccactgc aggatcacga
    12121 gattggccat atctggggga ttccggcagg gagcctggct ggccgcaagg tgaaacatct
    12181 ccaccagtat cttcacgcca ttcaatccgc cttgcaaaag gcgtcagccc agacagtccc
    12241 gacgacggga gcacttgatc tctggaaaga aacgcttgcc gtcttaggcg aacggccggt
    12301 tgaacgatct atcgcgctgt atgatggcct agaacgaact gaggaagccc tggtggaaaa
    12361 actccggacc ttcgcctggg gcaccctggg ggaggacctg gaggcaaagt tctggttgtc
    12421 actcgttcat ggtgccagct ccaacgccgt gcactctgaa aacacgcgct ccgtcttcgg
    12481 cttgcaacgg ctcctggcag tcctgtcgga gattgattcc agcccggacg cccttgaaga
    12541 agaactcctg gctcgtacag tggcgacccc gaaggatgtc cctgcactga ccgacgaagc
    12601 agcacagcca aaggcggaag agatggggca aatgcagcag cacgtgctga ccagtttcat
    12661 cggggagtta cacaacgacc ttcaacgcta acgcactgtc gacagctgca tggtcgattc
    12721 tggaacatcg gctggtttcc caccgacccg gcaagatttc tttttcaacc ggcttctcag
    12781 cggggagagt attttgtata atccacctat catgcagcac gatcatgtca tgattcctgt
    12841 ccggtcactg gcgagagtcg cgggtctgat gttgtgcatg ctggtcttgc ccctctcgat
    12901 catgccggtg gcttcgctct tcgctgcggg tctcgttgaa gtcacggaac tgttggctca
    12961 tcccgatcat tacaatcatc aggtcgtaac cgtcagtgga cgcgtaagca gttttcagct
    13021 tgccacgaat cgcgacggtc aaccggcatt cggatttctt ttgcaggaca ccgcaggaac
    13081 ggtgaaagtg gtgggtcttg gaaaggcgga tgttcgagaa ggtgactacg tcgtggtcga
    13141 aggaatcttc agccgattgc gccaagccgg tcgcgccatc gtctacaacg aaatcaaagc
    13201 cacctcggtt caatccatgg caaagatgaa cccggacctg gtcggctaac tttccccctt
    13261 ctttgccggt gctatctcct ctacaacccg gttgccttct ctctcgatat cgatcactct
    13321 gacatcgaag accaaggtct tccccgcaag cggatggttg aggtccagga caatgacctc
    13381 cggcttgatc tcggccacat agggaaacac aaccctcccg tcaggagccg tcgtttccag
    13441 cttcgcccca acgcgctgag cctccactgg cacacgatcc cttcggactt cgaatagccc
    13501 ctccggatgt ctctcgccat aaccatccac gggcataaca gtcacgcgtt ttgcagcacc
    13561 gattgccatg ccctcgagtc ctgcttcgag cccgcgcaag atctcatgct gtccgtgggt
    13621 gtagaccaac ggagcctcac cgacggttgt gtcgatgacc tgctcatctt cgaggcgaat
    13681 gacgtattcg actgagacga cgtctcctgc cgtgacgtgc atgtgccagt tcctttttcc
    13741 acagtctttg cgacggtgtg atcaattgcc cagactcgtg cgaaacattg tgctcaggtt
    13801 cgtctgcaac ggcgatggtc gtcgctaaga tggttccgac ttcgatcagc ctatcacggc
    13861 aatcgaccat ggtcatgcga attccggaag ctcagaggag cttcgcgaaa ctctgtccgg
    13921 attactcaag aaggatcgaa ggaggaatgg agggactgcc taccaatgcc ggaagggtcc
    13981 cgaatcgagg tgcacaaact ttccgcgcgg atagtacccg actccgccac agccaagtcg
    14041 caacgcgact tcccgaacag tccgcaaagg cactccggga atctggacat caaccgcctg
    14101 tcccgacaca tgataactat ggcgtgccgc gcgagtgccc attctgatga gctgttcgtt
    14161 atattcaggc gaacggtagg cggatacgat atgaatgtcc cggcggccac cgaccttctg
    14221 ttgaacgagt gtaacgaatt cgatgagttg cacatccatc gtcgtcgtct cattcgaatg
    14281 gtgacaccgc aaaaaataat tgaggtcgtc gagcgcagac tgatcgtatg ttccgctctc
    14341 tgtccggaac gtgactgaca agcgttcttc ggtctgcaga ttgaacaagc tgatgcgtcc
    14401 tgtcgggagt cgcgacgctc gcgcttttgc aggaagagcc aggttggcaa cgaatagcgc
    14461 cgtgcctacg gtgaccgtac gcaaaaaatt ccgtcgactc gacacagaaa gaacctcgga
    14521 tggcatcaat tcgtctcctc gcgaaacgtg cgagtcatct gtcgtgggca ctctcgcatc
    14581 acgccgcaat gtctgttgac agagacggtt cgcacacact ggcggacgca aactgcacgg
    14641 caacacaggc gctatgcaaa taggctgacg atacctcggg aggaaccagg ccagcagaga
    14701 ccggaagact cttcttctta acaaatacca aagaagtggt caaccaattt acactcgcga
    14761 gcggcgtatc cctgctgccg cagcgtcgct cgcctcgttc gcatgacacc ataccgcagc
    14821 agacacgtcc gagagatcaa tgctccgtca tcgaagcgcg cggcgagaga ccgggaaacc
    14881 ggcgggcctc aagagatcgt tccattccat attggcgaag tcgccggtac aacgtggagc
    14941 ggctaatgcc gagctcctgg gcggcccggc tcaagttccc ctgtgagagg gtgaacgctt
    15001 tcatgatcag gtccgtttcg atccgctgct gattgacctt cagtgagatt gatccgtcgt
    15061 cctgcggcgg ggcctggcga ggcaaatcca aatcggcagc ggtgatatgc gtgccttccg
    15121 ccatgaccac ggcacgtccg atcctgttgg ataactcccg cacattgccc ggccaggaat
    15181 aggcctgcat cgcctccagc gcctcacgag taaacccgta cagaggttta ttgtagtgag
    15241 cagcggcctg ccgcagaaac gccatggcga tcagcgacac atcctcgcct cgttcccgta
    15301 acggaggcag gttgatgtgc accacgccca gccgataata caggtcatcc cgaaaggtcc
    15361 ccttctcgat cgcttccttc aaattcacgt ttgtggcggc aatgatccgc acgttcatct
    15421 caatcgcctg atgcccgccg actcgctcaa acgtgtgatc ctggaggaac cgcagtaact
    15481 tgacctgcaa cgcattggga agttcaccca cctcatcgag gaacaacgtc ccaccctggg
    15541 caaactccac ttttcccttt ttctgcccga cggcgccagt aaaggcgcct cgctcatagc
    15601 cgaagagctc ggattccagg agactttccg ggatggcccc gcagttgatc ggaataaatg
    15661 gcccctgttt gcgtaatccc cgggcgtgaa tcgcacgcgc cgtcagttct ttgccggtgc
    15721 cgctttcgcc agtgatcaga atcggcgcat cactcgtcga caccttccga atagcatcaa
    15781 aaatccgatt gatactcgca ctcatgccca acatgccgct gaattcttcg ggcccgccaa
    15841 ccaccatggc cccgcgcgct tcctgttcca gatcggcgac ccgcgcgact cgttctatac
    15901 tctgcagtaa ttgcactgga tcaagggact tggcgaggac atcacaggcc ccgcactgaa
    15961 ccgcgcgcac cgccacactt cgctcaggtc tcccggtgta cgcgatgact ttcccggaat
    16021 accccgtctg acgcaatttc tggagcacat tcaacccttc ttcggcagac ggctgcgatg
    16081 gcgaatcgat atcgagcagc atgaccggcg aagcctgttc atgaatgggc aacagcgtgt
    16141 ccgtcgtcca cattgccgtc gagacttcga actcgtcctg aatcaatgcc tgcgccgcag
    16201 acaccgtcga ctgatcaggc ccgacaatta ctacactatg cttcgccacg attcggctcc
    16261 tttcggctgg taagaccacg ggcgccattc aggcaaacca tcgtctcacg aacggcaaga
    16321 tcgagataag gatgcggctc aggtccgcat gacagcacgt tacgagactg tcgacggagg
    16381 gtcgagcgag tcgcacataa acacatctcc accgaatgcc ttcgccagcg ctggcacggc
    16441 gccattcgct tcctgagcgg tgcgatccag catcgcgatg attggcactt gcgggcaggt
    16501 acgtttcaaa cggggaaccg ctgtctgcag cggcgtggag catgatgaca acccaacgac
    16561 aatcacatcg ggacgcagtt cctgaaggtg atgttccaaa tgaggcacag cggacgtcat
    16621 ggtggcttgg tatccatgga gcgcaaacca gtcggcatag cgatacccgc tggtgacatc
    16681 ttcataaatc accgcgaccg tcggccgttt tccggaacgc gccccattgc cgcctgttga
    16741 tgattgcccc ataagattcc ctccccagat gaatggcatc aggttgtggt gtgcatcttt
    16801 gcgagttgga ccaaccggtg tttcatttgc ggcccccacc aggtcaggtc ctgtaacatc
    16861 gcggcctctc gtgggctcag tcttgtcagg agatccgacc acccttgacg aaacgacccc
    16921 gttcgtcgat caacagatga tcgctcggca gccgcatggc cttgcgctgc gtcaaaaatg
    16981 gccactaatg tcgcggtatt agagatccag gccctctgca tttggaagag cataggccgg
    17041 gagggtcgag gaggctatca acagaggcgc tattcgtgtg tcacaataaa acagtgccga
    17101 ttcgtcatcg ttcgatcgac aaattcaggc acgtcagcgt cgttagacca cgaggccgtg
    17161 ctggagggca taccgggtca gctcggcatt gttcttcaag ttcattttgt ccagaattct
    17221 cgcccgatat gtgctgatcg tcgtcacgct caggtggata ctctccgcga tatcgctgac
    17281 ggtttgtcct gaggcgatga ggcacagcac ttcatactcc cgatccgaca atcgctcgtg
    17341 cggnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnccttcga atccttcctc
    17461 cagaatgtcc ttcactccac gccggaagga gggatgatca tcgacgacca gaatacgtac
    17521 ggttgctgtg tttcgcatcg ttccctccat catgcgctat ccctttcctt ctcgaggcag
    17581 ttgcaatgtg atagtcgtcc cgttgccttc caaggtctct atttgcacat ctccaccaag
    17641 cagcccggct cgctcccgca ttccgagcag accgaatgat cgggcatcgg caagtcgatc
    17701 ttgaggaatt cctcgcccgt tgtcgcggac ctgcagcaat aaccccacgt tctgctcttc
    17761 caagcgcacg tgcacttctg tcgcctgggc atggcgggtg acattggtca gcgcctcctg
    17821 acaaatgcga aagaccgcag tggcctgctc cgggtccaca cgcaaatcct catggctgac
    17881 cacgcaatga caagtaatgc cggtacgacg ttgaaaatcc cggcattgcc attcaatcgc
    17941 cgcgaccagc cccagatcgt ccaacacgcc ggggcgcaat tccgcgacga tccgctgcac
    18001 agaggtaatg gtgctgtcga cttgctcctt catgccgcga atcttctcat cgaccttggc
    18061 ccgatcgcca gaaacgagcc gctcgcccaa cagaccgccc aggcgggata aatcgatctt
    18121 caggcacgtc aggccgacgc ccagctcgtc gtgcaattcc cgcgcgatgc gtccgcgctc
    18181 ctcctcgcgt atcccctcca ttcggcccga gagttttcgc agccgacgaa gagaatcctg
    18241 caactgcgct tcggcgcgct ttcgatccgt cgtgtccttg aagacgacga ccgcgccgac
    18301 aagttccccg cgctcagaaa tgggcgtact cacatattcc accggaaaac tcgtcccgtc
    18361 cttgcgccag aatgcgctgt ccacctgctc gcgcacctcg ccgtcccgaa tcgtctccac
    18421 gatgggacaa ctcagcgcgc cgaacggtcg ttcagcgaga tcgggagaga acaccaaggc
    18481 ggataacgac cggccgatca tggcgtctgc ttcccacccc aacatcttgg ccgccgccgg
    18541 gttgacgaac gtcaaacgcc cctcgcgatc caccccgtag atgccttctc ccgccgaatt
    18601 cagaacgacc tgattgtgat aatgcaggcg atccagctgc tcctctgccg tccgccgttc
    18661 gctgatatcg cgcataatga tcgtgaaaaa cagatcggat tttcccttcc atgacgtcac
    18721 gctcaactcc aacggaaact cgtccccttg cttccggcgg cccacgagtt ccagcgtctt
    18781 gctcgttgat tgcacacgct ccagcacacg cacccgctgg acgttgcgtt ccagctcttc
    18841 atggtactgt tccgggatga tcatcgtaac aggctgtccg ataatttcct ctgccgagta
    18901 tccgaaggtc gcctccgctc ccttgttcca gaaggccacc ttcatgaggg cgttgacgag
    18961 gacaatggcg tctttggtcg attgcacgat cgatcgcagt cgttcttcgc tgacccgaag
    19021 cgcatcttcg atccgccggc gttcggtcac atcgcgaatg attcccaata cacccaccac
    19081 acgcccctgc cgcatttgcg gggtgccgac gaattctccg gttacatagc caccttgctt
    19141 cgtgctgatt tgcatcgaac aggtgagcgg cgtgccgcgc tcgagaatcg cctgcaacac
    19201 gtcctgacaa aatccggcat cgtctggatg cagtaaggtg gcgagcggtt cgccgatcca
    19261 ttgcgaacgg gaccagttgg tcaccgtctc aaatgcctgg ttgagggagg tcatggtcgt
    19321 atcggccgag agcgtgaaaa taatatcccg cgcgccctcc accagactgc ggaatcgata
    19381 ttccgactca aacaaggcat cctgcgcccg cttgagccag gtgatgtcat gaaacaccac
    19441 gacggtcccg cacagcagtc cagcgtcatc ccggatgggt ctggcattga tactcaccca
    19501 tcgccccggc actccctgcg aggcccgcat gtagacttcg agccaatcaa ccttttcccc
    19561 tttcaatgcg cgcgccagcg gccattcgtc gcgctggaat ggcgtcgccg tgtcgccatg
    19621 aaaaaattca tagcggtcta cccactcgat cgggggaacg tctccgggag aaaaaccgac
    19681 gatgctttcg agggcgggat tggccaagac cagtttcccc gctgcatcgg tgacgacgac
    19741 gccatctccc atgcttcgca ataccgaatt gacgattctg gtctgctcat ggagagcctg
    19801 ctcagaccgt tgcagcgccg tagccctgtc gtggagcgcc tgtttcgcct gtgcaatgcc
    19861 agccgattgt gtcctgaccg catcttcata gacccgcagc aattgttccg cgaccgccaa
    19921 acgcgactga tgacggagac ttgccggagg ctcaggcgct gatcctgatt gctggctcgc
    19981 accactgtct gtgcaagacg cttcatcaaa cgcgagcaag gatgttttta aactgagggc
    20041 gagtgatttg cacaacgccg cggtctcacg cggcaccggc gtcttggaga acaaaatcac
    20101 cgcgaataaa tcgcgcgacg gtaacatccc cccgaaacac aataccgact tcacaccata
    20161 tttcccgaca aatccgtcct ggacaggcac atagggactt cccaccgcgt cgggcacata
    20221 aaacacgtta tacgttttct cctccagatc gaccagccat tcaccatccg gcctcacgtc
    20281 gaactccgtg gacacaccga actgatgcag gagttgcgag aacatcggaa attgtttcac
    20341 gaaatcggcg ctgaccatcg gaatgacacg atatcggtga gaacgatcga ctcgattcca
    20401 atccggctcc gcgccggttg aggccacgag tgtgaaacag cgtaaatcgg ggaacggcgc
    20461 gatgccgccg agcttttctc tgaccagctg ttgatgttcg gtatccagcc ggctgtagga
    20521 aatggttttg aagcaccgga caaggacaca atcgcgttgc cccgtggtcg ggtcgccgag
    20581 cgtgtcgaaa agatagttca ccgccttcga ggccgcctcc tgcaaagacc gcgactgttc
    20641 gcccagctgg cgcaggacgg ccgagcattc cgtcatttcc aacagggaaa agcgagccag
    20701 actatacaca ggcgggccct cgggtgaacg atgggggatg actgatcaac gcgccactga
    20761 ttgacgggtg ccgggagatg ccgaatcgtg agggaaggcg cgtgtcgaga actctggcct
    20821 tccaaagcga ggcgcagaac cactctgaag gcgagtctag ttaagggcac caggcttgtc
    20881 aaggcaggga ggacggatat catcagacgc gtggtctgag aaaacaacag atctgttcag
    20941 atgaagactg ggagaaattg tcgctatcga gaggaaggat ccaactcaag cgcatgcgac
    21001 aataacgccg catcggacgc ataggtcagt cgccgcaggg cttccgtccg ctcaacccac
    21061 tgcacttctt ccacttctcc gtccggaacg ccggtcagct cgagcggaac catcttgaac
    21121 cagaccaccg tcttgcggaa tcgacgtccc tctcgttgaa accaatattc ggttgttgag
    21181 agatccgcat cgatgcggca agaccagccc gtctcctcac ggacttcccg cacggcggcc
    21241 tgcgccggcg tttcaccggc atccaggcgg cccttgggga aggaccagac cggacgacct
    21301 ttaatgtcgg acacccggat cagcaacact tcctgctgcc gcaagacgac cccgcctgcc
    21361 gagcggacca gtcctccttc agccatgccg ctgctctctt ttctgacgcc cgcttggtcc
    21421 gcagtgcgca acattacgca tgacgcgaca atcctaaaaa ccatgtcaga agacgatcct
    21481 gagcgctatc ggggagcagc cacttcagga ccgctctgaa gcgcgcatcc ttgccgacca
    21541 gataacgagc acgcggcgat ggcacggtca acgcacgggc caccacctgg gcaacggcct
    21601 cggcaggaat cgcacgggcg gcagccccgg ccatcacatc ctgcatacgc gctaaggact
    21661 gagcatacag ggccaacgat tctggcgcga ctccgccgag tgtgcgggtg gcggacattg
    21721 tggcccgctg ccatatctga gattgaatgg cgccaggttc gaccagcgcc actgcgatgc
    21781 cccagggtgc cagctccagc cgcaaggcat cactcatggc ctcgagcgca aatttggagc
    21841 tgcaataggc acccagaaac ggggtggcag ccagcccggc gatcgaactg atgttgacga
    21901 tgcgccctcg tgcccggcgc agcaacggga gcaaggcttg tgtcacggcc agcgctccta
    21961 tgacattgac ttcgaactgt gttcggacct cggcgatagg caagagttca agcgggcccg
    22021 ccacggagat accggcgtta ttcacgaggc cggccagccc cgcttccggc aacgcgtctg
    22081 tcaatgttcg acttgcctca gtgatcgaat cggaatcggt cacatcgagc agcagcacac
    22141 gcagacgagc ggaggtggaa cgagccaggg cctcgccatc ctccttacgg cgcacgccgg
    22201 cccacaccgt gaaacccaat ccgtccagat aacgcgcaca ggctgcaccg atgccagtcg
    22261 atgcaccggt gatgacgatg gctccttgca ctcacaggct ccactgttga gaacgtatgc
    22321 gccgcaccag aactcttgcc ggctgttcca tctcgcccga gattatcacg cgcatggggt
    22381 cggaggcatc aacgggcccg agggaagacg ccctcaggaa tttcagtagg gaactgcctg
    22441 cggaaagaga aagaggtcaa tgtttccggt tgtttgttcg acgcacggtg atgatatccg
    22501 ccgactgcgc accctgccgt tgaggcgaat ttgacaatcg ggcatcctca tctagacttg
    22561 attcatgcgc gtacacactt tcttttccag aagcggcaca gcgtcaagaa tgatggcgat
    22621 cttggtcctc tcgctgctcg ggtatttcgc tctgcttccc tccaccgcac aggccagtcg
    22681 aactctcgtc gtccccattt ctgtcgcaac ctataccgac acccaggtcg gcttcccgac
    22741 gttcgtgatg aaatgggacg agggggctca gccggatccc ttagcattgc gctgggggcg
    22801 tagccaggtt cctgttcgcg gaaccggcat ggcgtcgatt cagcacgcgt tccagtttgc
    22861 ggtcacacgt ctgggtgcct ccattcgccc gaccggaacc ctctcgctgt acgcgacatt
    22921 cacgggtccg ctcagcgaag agggatcaac ggcagaagcc gcgttggcga ttggattcat
    22981 cgctctgctg aagggtgacc agctgcgacg cgacatcacc atcacgggca cgttggaagg
    23041 cgatggtcgg atcggacagg tagatcaggt cgccgaaaaa acaaccgcgg cggccagagc
    23101 cggctaccac gtgctgctcg taccacgagg gcaattttat gcccctcgag tcaatcgagt
    23161 cagcttgacg ccggaatcga acgtcctcgt ccgagaagta gagacgattg aagaagccta
    23221 tgagatcatg acggggaaga aactctaacg tccccgccta ccccactccg caccgttcac
    23281 accctgtccg cttgttacct cgttcaaagc ttctacggat tggcttcaca tccagttgtt
    23341 gatcaacagg aatgccgccc agtaactcgg gtgcgtatgg ccgcgctgcg aaagaatctt
    23401 ttgctgtgcc cgttgcaagg ccacagcttt tgaaatggcg ggatcctgca actgccggta
    23461 gaattccgat accagttccg tcgtcgtttc atcatccgac gtccacagac ttgccagcgc
    23521 cgtcctcgct ccggtcttca cggcgagccc ggtaagcccg agcgccgcac gatcatcctc
    23581 tgcggcaatt tcgcaggagc tcagtgtcag cagatccagc ggctgttgac ggtattgctg
    23641 gagtcccacc agctgggaca aacggtccat cgtgatcttg ccatcatgcg ccagcacaaa
    23701 cgaatccctc gcctcggttc cgacaaccgt atgagatgcc acatgaacga tccccagtcc
    23761 ctggtccttg atctcctctt ccaaggtcgg cgtagagaac tgtttgttca tgagcagctt
    23821 cccgccatac atcgtcctga tcgcctgcac ttcggtttcg gcgtatcgcg gcgcggactg
    23881 gccctcgacc gattcagtca gccccaccga cagcacactt cccttgcggc gttgagctcc
    23941 attcatatcg gtcagcgcca gactcggcgt gactgcgaca gcgagcgaat cgacgagaaa
    24001 atgccgccca tcgtggagcg ctcccatggg aatggtcctg agcgagccgt cggccaccac
    24061 cacgagtgta tggacaccgg cgccttgcaa gtcctgctga ataggtgcca cgagccaccc
    24121 gtgcaacgtc tgcgcggaag acaggtaatt ctgtgattgc gaatcctgga tcagccgcct
    24181 gaacgaacgg atttctttcg tcagcttttc ccccgccaca ggaactctga cttgtttgag
    24241 tccgttggac gtttccagga gcagttcgag ccggtccgga aaggcgattg gatagatcac
    24301 cgccgtgcct ggcgccaatg cccccgcgcc tcgatgactc gcgaccgtcg cgacacaatc
    24361 gtcctggaaa taatcctgca gctcggctgc ccgcgacacc tcaatcgttt ccttgacctt
    24421 caccagcaac tggtcatttt gctcgggcgt cttcgccgcc gccgctctcc gcagcaagac
    24481 atcttcatat tcgacaaaca atggagccac ggattcgtag tacgaatgat gccgtccttg
    24541 atatccgacg gaatattcat agtgaatcgg cttcaacagc gtcacggcac gctgatacgc
    24601 ggccagggat tcatcttcct tgccctccgc gcgcaacaat ctcgccgttt gccactgcca
    24661 gcggtacagc gattccggcg cattcacctt ttgagcggcg aacgtggctt ttcgcgtata
    24721 ctccagcgcc tcgggattgc gatgctcctg ctcccgcaat ccacccagat annnnnnnnn
    24781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    24841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ncaaacgcgc cttgctgaaa ctgtgtcgtc
    24901 ccctgtcgca tttcttgcgc cggcgtgatc gacgacgtgc tagagccgcc caacaattcc
    24961 agcgccatcc cgcttgctgg ccaagtgaag ctgctcaacg ccatcactcc aaggctcagt
    25021 atcgtcaacg gagacgacag ggtacgcggg ccggccgaac cagcagcccc atggctccgc
    25081 ttcatgccgc ggcgagtgac catattacgc atcgtaggca tgacgtcctc cttgggcaac
    25141 tagcacccct gccatgattc cataagttgt gcgatcgtct gaccgtgaat gtgggctgat
    25201 ggtgctgccg gagcgccagg ctcgagatcg ccggcgatct cctccagcac cacaggcgcc
    25261 gccagagacc ggcctggttg cgagggcgtg acgtcgcgag aagcttgcac cagactgctg
    25321 aaggtgccgt cttttcgtgc agcgcaccgg ctggtcaata aaggagccgg cggagccggg
    25381 gcttcctgag gaagcaccat ggcggcacga ttcaagaacg cgacaggttc gacgggattc
    25441 gtcggattga cgttagctgc atttgcggta gggagaggcg gaaggccgcc aagattcacg
    25501 ccgaccactt ggatttgcgt cacacgttgc gtgaccgaat tgctcgtcgt gttgacctgt
    25561 gcacccgtcg gcacggtgac attcggactc acgtcaattg aggcgggaat gactccacca
    25621 ccgcccgcga cgatcaacgt tcccggtaac gcttgcactt ggccattacc agccgccccg
    25681 gaaaagggat ttccaacaaa tggctgggta ctcatttccc ccgctgaact cgtactgccg
    25741 agcatgaccc gttgagcgct gatctttgat ccgttgatct gaatgcctcc tcccatgaga
    25801 cccaagacgg cgccggtctg gaggactgtc gaagaagagg tcagcacgat ggacccgtaa
    25861 gggccctggc ctaaaaatcc gaacgccact ggtgaactgg cggacaaggt tgaatcgaaa
    25921 gccagcaggc tggtgctcgc ggtaaagatg cctccatcgc ttagacgtag ttgctgagcg
    25981 gtgctgaaat acgcagatcc ggatacgttc aggtgggccg atgggccgaa tatgattccg
    26041 gaaggattca gaaagaatag attcgcattg agggcttgca ccgtgccgtt gatgttggac
    26101 ggtgatccac cgatcactcg actgatgacg ttcgacacgc caccaggatt cacgaatgac
    26161 gccacatctc ccgctccgac cgagaattga ttgaagctat gaaagagatt gggaccgcct
    26221 cccggtctcg tccccccggt aatgttggtc gtattgcctg ccgtgttcag cgtggttcca
    26281 agaccgcccg gtccgcctgg agttgcgacg atgttggtgg cctgtccgta agcgatcgat
    26341 gcggtagagc cgaggagcat caggaaggcg agatatccac gaaccaacag cggcaatcct
    26401 gcggggcgac atagcatggt caatctcctc atgtggtaag agaggccacc tctcttacct
    26461 taaacgacac acaacttcaa cacgcacacc ctgtccggac ccgcgagtac aagggccgag
    26521 acctggccaa tcggccctgg atattcagcc ctaacaaagt gcatgagtcg cctgtggctc
    26581 acgtgcacaa ccaacggcaa aaaaacgccg tcaacgtgga gggggttatt taccctcaag
    26641 gacaacatgc tgcctcagcg agacaggcgc gaatccatcg catccgcccc tctctcgcta
    26701 aaaagcctct acgaccagtt gcagatggat gccgtgatcc tggaggttgt tgcgatcggt
    26761 atcgtatcgc ttcaactgtt ttccataata gagttcaaaa tgactcccgc gccaaaaatt
    26821 ccagatcacg ccagcaccaa gactggccaa tgttttgggg ggagtaccgg gagtctgggc
    26881 agtggtttgc cagccatggc cgaaatcgaa aaagggtgcc agaaagacgg agtccacacc
    26941 cgcctttgtc gtatagaccg gcactcgtgc ttcgatcgac gccattgcgg cattatcccg
    27001 aatcagcgtg aactcgcggt acccgcggac gctataccgt ccgccgacgg caatttgttc
    27061 aagcgggaag aggtgatcgt tggacaattg caccaccccg cggctcacta actgcgtacg
    27121 ccaaaacgga agttgccgga tccactgggc ttcgcccaac caggaaaaga accgcgcatc
    27181 cggcaggttc ggatcagcat tggcggtcgc ccccatcgct ccgataccga cggaaaaccg
    27241 cgacaagagg gaaatcacct gttcggcgga acgttgggca tactcctgcc cgaaacggag
    27301 cgcggtcaca cggaatcttc cgttcggcgc cccggtgatg agctcaaacg gattgccgcc
    27361 caacgtgctc tcattcctgg catgttcgcc cgtgagggaa aacgccagct cctggtcagc
    27421 cttcctgatc acggggtgcc tgaccgagag gccaaagatc tgagccttgt tcttgatatc
    27481 caatgaatcg aacggcgact cctcgacgcc gaaatcaaac cggcgatatt gcagtgcgac
    27541 ggtcgtatcg cgagggccca ccggaatttc atatttaaag ttgagcatcg ggttgacgcc
    27601 ggccgagcga ccatattgca aactcagcgt atcgccgaag cccaacaggt tctggtgagc
    27661 taacgtgatg aagccttgtt ccgcaccgac gacgggagac tgatagttgt tgaactccaa
    27721 ccaggccttg agcgggttgg cttccttcac cttcacattg agcgtatttt ctccaatcgt
    27781 ggcgcccggc aacaattcgg cattgatccg ttcgatccgg ggattggctt gcatcacgcg
    27841 caaccgttcc tggagcgctt cgacctggag nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    27901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    27961 nnnnnnnnnn cgtaaaggcg gtattgccga ccagccggat atccttgacc atgatcttgg
    28021 gtcccttggc cgcctgatcg agcgcaccag gaggcgtggg ggtcgggaga tcaagcgcag
    28081 ggggctgtgc gggcggaggc acaacgggta actggggcgg tttcggaggc aacggcccga
    28141 gctgcgagcc ggtttgtgag tgagcgggca cgaccagcgc gccaagtaac agcacagccg
    28201 ccacaccagc aacggttcca cgccatctac gcaacacatc cccgcgattg gatgaacgac
    28261 cggacgcatc caaacgcgcg tcagccgccc cgtatattcc tgatgcctgc cccactgatt
    28321 tcttcacaca agccatcaag gcctcccctc tttcttgatg acggggcacg cagattcgtg
    28381 aatcagtgcc cgtaaaatca tcggctttcg atatttgtcc tgaatcacac cgctgctgcg
    28441 atctgcaaca cgcactcttc agaaacaact cgcagtcgcg cgacagtcgg ctatcggccg
    28501 tggcgatacg taggtgtttg gagaatccgt cctgcgaagg aactgcttat aacatgtctc
    28561 gacgcaaatt actcctgggg ccacaaagtt ttttggtcgg gggaaatgaa tgggtcaggt
    28621 tggaacagcg caggcgacag gagagtcacg gtttctgaga tgggacacgt gaaggcaggt
    28681 caacgcggag tcggtcgttg tatcgacatg gtctatccgg cccgatgatg tacgtatatg
    28741 ccgatgcagc cccacccgct atgacaaagg cgcagcggcg aatcccgcgc cgggccatag
    28801 catctcggca agagtctctt cctcgaaccg ggcggtaaaa tgtcgcaatc gaggagcctc
    28861 gtaagtcatg accaaccctc cgatggaatg ccggcgttgg tagagatcca ctaacgcttc
    28921 cgccacgaag gacagatgct ggctggtata gactcgtcgg gggatcgcca atcgcacgag
    28981 ttccaatgcc gggtagatcg tttcctcggt cgccggatcc cgcttgccaa acatgaccgt
    29041 tccgatttcg acggtgcgaa cgccatagtc ccggtacagt gccacagcaa gggcctgcgc
    29101 cgggaattgg gattgttgca ggtgcggcag gaattccttt gcattcacat agacagcatg
    29161 gcccccggtt ggcttcacga tcgggacgcc gccctcttcc agcagggctc ccagcgcctg
    29221 cacctgtccg atgcgatagc ggagatactc ctcgtcgagc acttcctcga gccccctcgc
    29281 catcgcttcc agatctcgcc ctgccagtcc gccgtaggta ggaaatccct cgacgaggat
    29341 caacatgttg gtcaccgcct gcgcccatcg ctcatcattg agggccagga atccaccgat
    29401 gttgaccagg ccatcctttt tggctgacat gagacagccg tcgcctaggc ggaacagttc
    29461 tctggctatg tcacgaattg gtctatccgc ataccccggt tcgcgctccc ggataaaaaa
    29521 acaattctct gcaaaccggc aggcatcgaa gaacaacggg atgccgtaac gattcagcac
    29581 ctgcctcgtc gcgcggatat tggccattga gaccggctgg ccgccggcgc tgttattggt
    29641 aatggtgatc atgacaaagg ggatttgcga aggcccgacc cgcttgatgg tctcctcgag
    29701 tcgagccacg tccatattgc ccttaaacgg cagttcgcaa tgcggatcgt atgcctcttt
    29761 gatgaccaga tccttcgcct ccgcctcctg gtgctcgacg ttggcccggg tcgtatcaaa
    29821 atgaatgttg ttcggcacgc acatgcctgg tttgagaacc gttgaaaaca acacatgttc
    29881 ggccgcccgc ccctgatgcg tgggaatgac gtagcggtac ccgaacaatc cgcgcacgac
    29941 cgtttcgaag tgatggtaat tcttgctgcc cgcatacgac tcatcgccga gcatcatccc
    30001 ggcccattgg gaatcactca tggccgatgt tccgctatcc gtcaacagat cgatggcgac
    30061 actttcggca gggacatgga agaggttgta cccggcttcg cgaagcaacc ggtcacgctc
    30121 ctcgcgggtg gtgcgcttga cgggctcgac gactttgatc ctaaacggct cgaatgggaa
    30181 gttcacggat cgacctcctg aagtaggcca actgctcgtg aaacggtccg gatccctggt
    30241 agtcgaatac gtatcgcgtc atgtcgaaga gcggcgccgg atcgagttct cgaatcatct
    30301 ccggcttcca cgaaatctgc agacgattga tcatcgtaat cggcgtcggc gtgccgacca
    30361 tcccgagcgg cacgctcccg taggtctgcg aaaaaatcaa aatttccctg tcgaacatgg
    30421 ccgtattcat gtcttcggcc gcgccgtatt ttctgaagtc ttcttccagt cgctggaaag
    30481 ccggcgagtg aaccagcgcc tcccggaagg cataaaacac tttcacgccc gcacgccgct
    30541 ggtcatccat cacctgtatc gcatcggcca cggtggcgtc gtgctgcatc tgctcctgcg
    30601 tgagaatcag cagccgccga atccggacgt gacgccgcgc cgccgcttga ttcgccagca
    30661 gatagttggg atagagcgct tcgcctttct tccaaatatt ccagcgttcc atcatggcat
    30721 cgacagactg ttccgccgtc tccatcagac gcaccgcctc ggcgttcgcc gccgcccctt
    30781 catacgtcag agtttgcgcc tccaactgtt tcaattcccg accgatggct tccaccttct
    30841 tcggcagata ccggggccgc ttcggcacat gcagcatgac atctaccgcc gtgagggcca
    30901 gggtccagta ttctttggcc tgtttgggag ccttgtcttt ttgcgcgatc aacagcagtt
    30961 cgaccggatt tttatcgagc agcttggcca tcttgatgca caattccggc ttggggatct
    31021 tcaggccgcg ccgcatcaaa ttcgcctcgg gctgcgcgat ccccagcttt tcagccagtg
    31081 cgtaatcact gctcaagtca taccggtcct tgaccgcatc aaagtacctg gcaatttcca
    31141 tcatgtcgct cccggcaact cgtgatcttc actgacccgg cgatctacag acacgcactn
    31201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    31261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnna acggctcagg attaaacgcg
    31321 gcgctggttc tcgaacagaa gtagctgacc agttgatcca gatgcggttt gccgcgttgc
    31381 tcctgccggg acttgtacca cagcgctgtt tcgacggcaa agagatgcat cgcggcactg
    31441 accaggcgcg tcatcaaccg ttgcttccgg gccagtccct gccggtctct cgcggcaacc
    31501 cataacgtcg tgcgggccag ttcgcgactc tttcgcgcca cgaaacgctc ccacaatgga
    31561 tcgaacgagc cggcttctga gtcctgttcg tataccgtca gaccgccgaa tgacctcgct
    31621 gcggtgttga cgaaaaacgg cgtggcccgc accatgtcgg cgatgtgaca atcgaggaac
    31681 gcctggccat gcgtaaaata ctgtgacagc ccttctcttc cgatccagag ggtcaagatt
    31741 ccgttgctgc cttcccaaat gacgttgatc agcgcgtcac ggatcatccg ttcaatcggc
    31801 gccggcaggt cgccatggag acgcagggag tccggggtct caaacgcacg tccgccatag
    31861 atgcggaaca ggtcgagcaa cgattccagg agccattccg tcgcgaggat ttttgcggcc
    31921 gcggactcca accgtacatc ctgcttcgta tcggcccaga tgccggtgat tttcacaatg
    31981 gcttccagtg cgagcacgcg ggaagccatg agcacgatct tcgcgccgat gtcggtgtgt
    32041 tcgccgatcg ggcgatcgta ttgcttacgc tgctgcgcgc gtagacgagc caaccagaga
    32101 cactgcttga gattcccgag gcaggcggca ggcagcgtga gtcgtcctac ggtcaggctt
    32161 tccagggcgc gccgcagccc ctcgccctct gctcccagcc gatccgccac cggcacccac
    32221 acctcgcgca agtgcacctg accattgtag ataccgcgaa cgcccataaa gctaaggcga
    32281 gtgcaggagc accctcgcgt gtgggtgtcg acgacaaagg ccccgaaacg ccgttcttcc
    32341 ttggcgcgat ggatgtcctg gggtgagtcg acaatctgtg cgatcacgac gagccatgac
    32401 gcgagaaatg cctggtgccc ctgcggcgca ttggtcgtat acagtttgtc gccggtcagt
    32461 cgatatccaa ccaacaggcc ctgctcatgg acaggaatcg cataggtttt aagatcccag
    32521 atgtcacaac ccgccccctt ttccgtcagc gcaaatccgg agacctctcc cctggccaat
    32581 cgcggcagca atcgttgttg ctgctcggag ttcccgacca acttgaccgg ttcggccgcc
    32641 ccgatcgaat tgtgcgccga cagcaacacg gtggtcgccg catcatgact gccgagcaac
    32701 gtcgccgcct cgtgatattc cgactgagtg aagtcgagcc cgccgtatct gcgtggaatt
    32761 tttatgccaa acgccccgat ctcccgcaac gccgcgaaga catcctctcc gatcaggccc
    32821 tctcgatcga tggtttcggg gtccactttc tcaatcaaca gatggcgaag cctgtcgaga
    32881 aactcgcttg ccgcgccgct cctggcaggc agcgacgcgc gcgaatacag atgacgccgg
    32941 acgttcccct cgaacagacc agagagaaac cctgaataga gtcgcgtgtc acgagcggct
    33001 tcggctaccg cgagcgatcc tgtgaacatc cggtctttgt tggccattga tgccctctgc
    33061 cgccctgagt cagcgggctt tacgccaggc ggcgccgatg ccaccgatac gcgcagcggt
    33121 ggctgcattc ggcacaacgc gcggggccga agtccatgcg acgtgattca gtcgcgcgag
    33181 acgttgtaca gcacggtcct cgaagcgggc gcgagagatg gtcatgccat atgaagcaag
    33241 ctgtgcggat acgtgatcga attgatctct gaccaaggtc atgaccgagc catatccggc
    33301 gcgcaggaga tggatacggt cgcggtaact caaaaaactc cgttcgaaca agagcgcgtc
    33361 ctcctccacc ggcgaaatca cgaggacttc cttcgcggga tactcgtgct ggaaccgttc
    33421 caaagcctga gagaagcgcg cgtcgaagtt gatgcgtgaa gcctgttcac cgatcgataa
    33481 aaatccgcga tcccgcaaac gaccaacgct gctgccatgg tccgggacat cgaccggcag
    33541 ccggcgttga agcgggcgtg ccatcggatt gatcatgatc atgaaatcca ccttcttatg
    33601 gacggccact tcgaaaaacg ccatgcgccc gattcctgca tcgatgtaat cgcgcccttg
    33661 aatccgtacg gggcagaagt agatgggaac cgccgaagag gccgtgaccg cgcgagaaat
    33721 cggcacctcc tgccatcctt cctcgccgaa caggacattc tcccctgttt ccagatcaat
    33781 ggcggggata tagagttcct tcgataggcc ggcaaaagaa ttgctcaacc ctttggtttt
    33841 gtagaggccc gccaggtaga gggcgaatgg ttcgagcgta tagatcccgc tcgggagcgc
    33901 atcctgggcc ttgtcgagaa ggtcgatgag cgtcatctca ccgtagtgcc gcacataata
    33961 tttcacaagc ggcacgagtt ggcgggtcac gcgccagaac gtcttgagcc cttccccaat
    34021 ggcaggagag aacacgttgc gatgatcgaa ataatagggc ctcgtcccgg acagattggt
    34081 ttcgaggatg tctcggggct tcacgccatt ggcgatcaac gatacagccg ccgcacctgc
    34141 gctgacaccc acgtagagat cgaggtcgtt catactcacg ccgtcctcga acaaatcgtc
    34201 caacgcggtc aaggccccga tctcaaagag gtagccggtg aagcctcctc cgcccaaggc
    34261 caaggcccgc ttgccgaacg ccgatgccat gacacccttt catcggcagg gttgcctgca
    34321 cagtcgttaa cggtcgatga accgcggctg acgtttctcc aaaaacgcag ccaggccttc
    34381 ccgcttatcc tccgtctcgc agagaccgcc gaacagaacc gcctccaagg cgaggccttc
    34441 cggcagactc atgtccgcac cactacggat ggcccgcaac gacgcacgca aggccggcag
    34501 acttttggag gccatcttgc gagccagact gtgggcctgg tgcaacagat cctccggcgg
    34561 gaagaccgca gagactaatc caagcgcctt cgcctcctgc gccgagatcg gatcgcccgt
    34621 taaaatcagt tccagcgctt tggattgacc gacgatccgg ggaagccgct gcgtcccgcc
    34681 aaatcccggc atgatgccca aattgatttc cggctggccc aaccggctgc cctcagccac
    34741 gagtctgatg tgacaacaga gggccaattc cattcctccc ccgagacaga ctccattgat
    34801 cgccgcgatg accggttttt ccagagactc gatccgattc aggatagcct gcccttgccg
    34861 cgcgatggat gcgccttcct gcgaggaggc aatcgcggcc aacagacgga tgtccgcccc
    34921 ggcaatgaaa aaccggcccg tgcccgtcag cacgacgact ttgatggcct catcggtggc
    34981 gaacatctcg aaggcctggc tgagctcgcc gagcaattcc ggcgtcagcg tattcgccgg
    35041 aggatgatga atcgtcacgg tcgccactgc gccatcacgg tgacatgcga gcatcgaacc
    35101 ggccgtggta gtcatgggaa cctcacctca ttcgagcaat ggttggttcg taagagaaaa
    35161 accctctccc cgccccctgc cctgtaaacc cggcatccac caaacgacgc aacatcggcg
    35221 ccggccagaa ccgtggcccc accctgtcct gaagctcctc caattcctga agcacgcgat
    35281 cgataccaag ctggtcagcc agatggagcg ggccgatctt gtcgctcgga aatcccgttc
    35341 ccgccgccat ggcaaagtca atgtcacgcg cggacgcgac accttcctgg agcgcaatga
    35401 cggcctcgtt caccatggca acgagaggac gtaaggggga ccatttcatt gaacttcgtc
    35461 ccgtaagctg ccgtgcctgc gctctcagac gttcgaggtg ttgatcggcg ccaccttcct
    35521 cggcggcgcc gtaatcatac aaccccttcc ccgtcttgag gcccatccgc cccgccttga
    35581 cgaacgcctc cagcagtggt gcgggcgcca tcctgggccc atacgaacgg tgcagaatgc
    35641 gcgcgacatc gagcgcaata tccaagccga cggtatccaa cagagtgaat ggtccgacag
    35701 gcatgccgaa ggaaaccatg tcctggtcga tctctttgat ggagacatcg ccgtcctgca
    35761 ggcaccagac ggcttcattc aaatagggag acaacagccg attgacgagg aagcccgcac
    35821 actccttcac gatcacgggt tgcttccgca ggctctccga aaaaccgacg acatcatcga
    35881 ccgtctgcgg atcggtgccg agaccgggga tcacttccac caggggcatc gcataggccg
    35941 gattgaaaaa atgcagaccg atgaccttgt ccggtctctt ggtggcggat ccaatggccg
    36001 agatcgaaag cgcggaagtg ttgctggcaa gaatggcgct gcgggaacag atccggtcca
    36061 gctcctggaa cactcgctgt ttgagcagca ggtcttcaga cacggcttcg atgacaagat
    36121 cggcatcatg gagcctctcc agattcgggg atgccgtcac cagcagcatc ttttcttcca
    36181 attgctcggg cgtcatcttg cccttcgcga cacgagcttg ataaatcgcc cgtaccgatt
    36241 cgacgcctcg cctggcaaga gcttcctctc ggtccgccaa taccaccggc aggccggcaa
    36301 aacttaccac ctccgcaatc tgtgccccca tggtgcctgc accaaccact ccgactttgt
    36361 agatatacat ggcgtcacca cacgttcccg gtgaggtcca tcttggtcac tgcagctcac
    36421 tcactcatca ctcaacactc ttcctcagat ctgctccagc accatggcgg cgccctgtcc
    36481 accgccgaca cacatggcca ccgcgcccag cgccgcaccg cgacgcttca tttcatagag
    36541 aagtgtcatc accaggcgcg tgccggtcat gccgaccggg tgccccaagg caatcgcgcc
    36601 gccgttcaca ttgacaatgt cccgtttgag ttccaatacc cgctccactg cgaggtactg
    36661 cgccgcaaag gcttcattca cttcgatcag gttcagatca gtcagggtga tcccggcgcg
    36721 cttgagcgcc agtgggagtg cttctgccgg cccgatgccc atgcgggtcg gctccacccc
    36781 gataaaggcg taactcttga tgcggcccag cggccggtgg ttcagatcgc gcgcccgggc
    36841 gcccgacatg acaatcgcgg ccgcggcacc atcattgagc ggacaactgt ttcccgccgt
    36901 cacggtcccg ccttctttaa ataacggcgg gtagagcgcg agttgctgtt cggtcaagcc
    36961 gacattcggg ccttcatcct gaaccactgc gaccggcggg acctcgcgtc cggccaccgt
    37021 tttttgaacc atgaccggga agacctcatc tttgagacgt ccttctctga tggctttgaa
    37081 cgcccggcgg tgactttcca cggcaaagtg atcctgctcc tcatggctga tattgaattc
    37141 ctccgccaag ttctccgccg tcaggcccat caactgaccg caaaaggcat ccgtcaaccc
    37201 ttcccagatg ctgtcgataa attccgcgtg acgaagccgc tttccccacc gcatgtcgcg
    37261 tgaaacgaac ggggcacggc tcatgctctc gactcccccg accacttgca catccgcatc
    37321 ttcgctttga atgttttgat acgcgttcac gaacggctgg aggcccgacg aacaattccg
    37381 ctgcaccgaa taggcaggag tccgcaccgg aagaccggcc atgagcgcga tcacacgcgc
    37441 gacattgtac gcatcgctgg tgtgtcccac cgagccgatg atcacttcgt cgatgagccc
    37501 gggatccaat tcagcacgtg ccatcacttc acgcaccgct agttcgccca ttttatgcgg
    37561 cgtgagatct ttcaatgctc caccgaagtt gccgatgggg gttcgcgcgg cggcggcaat
    37621 gacgacctct ctcacggaag cctcccttcc actctcacac ggccttacgc ggcgcctgtg
    37681 ccgtcccgac aggaacctca gcctcatcac gcaaagccct tcgcagcacc tttccaataa
    37741 tggttcgcgg caactcggaa cggaactcaa cggccaccgg cactttgaat cgcgccagag
    37801 acttgcggca gtggtcgatg agctcccgtt ccgtcacgga cgattcttct acgggcacga
    37861 caaaggcctt cacggcttct ccgtaatgac gatcaggcat gcccaccacc accacttcgt
    37921 gcaccgccgg gtgttgaaag agaatttctt ctacctcccg gggatacacg gtctcgcccc
    37981 atggcttgat gacgtccttc ttgcgatcga ggaaaaagaa aaacccctgt tcgtcccgcc
    38041 tgacaatgtc tcccgtatga agccagccgt ctcgcaatac cgcctgcgtg tcggcctctt
    38101 tctgccaata tccccgcatt acttgggggc cgcggacaat cagttcaccg gccgctccgg
    38161 tcggaaggtc tgtgaggccg gtttccagat ctacgatcct cgcctccgtg tccggaaacg
    38221 gcagccccat cgagccggga ggatggtccc gttcgatcgg gttgcaatgc gtcgtggggc
    38281 ccgcctccgt caacccgtag ccttccgaaa ttttcactcc gctcaaacgt tcaaaggcat
    38341 cctgcacttc cgccggaagc ggactcgctc cgcagaggca cacccgtatc gaatgcaggt
    38401 cgtaccggcg gacgttcgga gaatcggtca tcatggaaaa catcatcggg acgccggaca
    38461 tgatggtcac gcgatgttgt tgaatcgcct ttaccgcctc gtcggcatga aaccgcggga
    38521 gcagaataat ctgcgagccg gttgcaatcg ccagattctg gcacgtgttc aacccgtagc
    38581 aatggaacaa cggcaccgcg ccgagaaaca cttcttttcc ctcgcggaag ttcgcacacc
    38641 agaaacggcc ttgcatggta ttgaccacca cattgcgatg cgtgagcatc acgcctttcg
    38701 gtatgccggt tgttccgccg gtatactgaa tctgtgccag ggcgcccggt tccaaggtgg
    38761 gaagaggctc ggtatcaaca tcacgctctc tggctccccg gtcgagcaag gcacagaagt
    38821 catacaccgg tggatacttc tcgaccgaga tccatcgttt cgcccaacgc gccttgatcg
    38881 gataaagcca tcgtttcagg ggcgggagaa aatcccgcag actggtgaga atgatccggt
    38941 ggagcaatcc tgtgcgttca cgtatggcct ggaggcgtgg ataaaacaga tccaatgcga
    39001 cgatggtctc gctgccggca tcatgcagct ggccctcaat ttcacgctcc acgtacaggg
    39061 ggttcgtcgg cgtcacaacg gctcccgcct tcaacacgcc gtaatacgcg atcaccgctt
    39121 gcgggatatt gggtaacatg agggcgaccc gatcgccggt ctcgacgccc aaccgtcgca
    39181 gtcccagcgc gaaccgggtg cttagttcgt tcaactcctg gaaggaaata cgtgtgccgt
    39241 agaagaagag ggcgggcgat tcgggaaacc gggacgcgga gcgccgaagc agatccggaa
    39301 ctgtccactc cggatagtca caggtagcgg agacaccagg atcatatcgg ctgatccaag
    39361 gccgcggcat ctggtcctcc catccctgac cgatcaggga ggttacccgc gtagctcact
    39421 ctccagcccg tgtaccggtc gtgaccgaga ctgggccaca ccggccggct tccgttcgag
    39481 tcccatccaa aatccttcaa gatagtccag tacggcattc atcccaagac ggaagtcgtc
    39541 tttctccttg tcagacatgc gagcgtgagg agcatgactg tcaccatcga cggcgacaat
    39601 ggcatgttgc atcgctcgtt catgttcaga ctcgagttcc cgatgaaaga cgaaatacgt
    39661 catgtccatg tcggcatagc gctcggcgcg caaacgcgtc agcccgggaa tgagatggtc
    39721 ccacatggta atcgccatat tctccagacc aaatgacgcg cccaatgcca tcgcatggtt
    39781 tccactcccg taaagacgct ccattccttc gatataggcc ttggtggacg gccgcatcgg
    39841 cgtggtcatc gcgacgtgaa tgtcgatgcc cagcgatcgc aggaagtttc gatacagcaa
    39901 ttcgtgccga tgtttgacgg agccgtcccc cagctcggaa tagaggacct tcgtcaactc
    39961 atcggcgacg gcttcatctt cggtgttgac taattgggca gcgaggatac gggggaagaa
    40021 gcgcgagaag ttataaaatt cgacggcgaa ctcacgaaat tctttatcgc tcacatcgcc
    40081 ggcgagaaaa cgatcgaggt aggaattatt aatcgcgcca tgtcgcagca cgtccgagcg
    40141 cacttgttcg taaaacgaca tcgtgcacct ccgccgttgt cccggtacgc cgtttcattg
    40201 cctgctcgcg cgcgattggt tccgaactat catgcatcat gatcaaataa tacaaaatct
    40261 atattgaatg atgcaactct tatgttgtag agtgtgctca tgcttcacgg aataagattt
    40321 tctgacacgc ggcatcggct gagattcccc gtgactacac ctgggaggaa ccgccatgaa
    40381 agaagccatc ggggttgatc acatcacctt gtgcgtgaag aatctctcgg ccacgaaata
    40441 tctcttcact catattcttg gctttgacgt catctggtcc gcccaggatg taggcagcga
    40501 aaaatccagc atggatacgg tcgtcgtcca gcggggcgcg gcgaaaattg ccttgatgca
    40561 gggcagaaat aaggagcgca aatctcagat ctgtgaattc gtcgagacct atggcgaagg
    40621 cgtgcagcat atcgccctcg aggtcgatga tatcgaggcg gtctgccgcg aatgggaaca
    40681 tcatggcgtc cggttcagcg gagacatcaa ggatggacgc gacgggttcg gccctctccg
    40741 gcaacgcttc acctacccgt tattccccgg ctgcggattg tttctcgaac tgacacagcg
    40801 gcagcatggc accgaagaat ccaaaacgtt cgtccgcgcg acggtcgagt cgttgtaccg
    40861 ggacatcgaa cgcgatcaga tcaaaggagt ggcacggacc atcatcgatt acgaaacgct
    40921 tccgcttccg tttgaagaag aagtcgaagc tgcatcgttg cgacacgcat cgtaaacaca
    40981 tcgagccgca cctga
//
LOCUS       DAOQPD010000027        38592 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_428_length_38592_cov_23.851857, whole genome shotgun sequence.
ACCESSION   DAOQPD010000027 DAOQPD010000000
VERSION     DAOQPD010000027.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 38592)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 38592)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38592
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_428_length_38592_cov_23.851857"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..2557)
                     /gene="glnD"
                     /locus_tag="PK063_08395"
     CDS             complement(<1..2557)
                     /gene="glnD"
                     /locus_tag="PK063_08395"
                     /EC_number="2.7.7.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008773 - [protein-PII]
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0018177 - protein uridylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[protein-PII] uridylyltransferase"
                     /protein_id="HMZ97108.1"
                     /translation="MSHALDAGFHMVQDAAAIPVSQLLAEQRQAIQQRLLAGASGDEV
                     VAATTDLVDGLIIGRYRTAARTGGEALTTAGFQHCCLVAIGGYGRRELAPHSDIDLMF
                     LFHQDAAKVIPELVKQVLHPLWDIGFQVGHSVRTIQDCIDLGLADLTVRTSMMEARFL
                     TGSPELFQQFHARYVRKVVSSGFDGYLEQKVAERQREYQKFGETVYLLEPNVKKSKGG
                     LRDLHLLQWIGSARFQAPTIRELSDRGILSQSDYRSIKEAREFLLRVRSFLHIRAGMA
                     QEILTFDEQVWLAKHLGFTDRPHLLAVEQFMQQYYRHTMGLHVALMRFVERCRRRSLW
                     QRLVRWLPSPRIQQYFSVDGEALTVPVELRSQVLVQPTLLLTLFNLARSRQLSIDPSL
                     LEDIHRHAETLSVEQFHTPEAGQTFLSILAGPGTARTLEAMHRAHLLEKLVPAFSRVR
                     GLMQFNQYHKYTVDEHSLLAVAKAETLADHSGVLGEVYREIKRKDLLHLALLLHDLGK
                     GHEEDHSEVGKRLAEETAARLGFDEPDTRTLVMLVHRHLLMAHTAFRRDPYDEKVLLP
                     FAREVGTPEVLRKLLALTAADIAAVGPDVLTKWKESLLVELYLRAMQEVSGERETADE
                     PQRLARIADDVAGQSQGDHNLPADKTWICSELEQFPLRYVYGTSPLRIAAHLGAIRRL
                     QEGGVVVETEFNAPLGTCEYAVIAHNDLIPGLFSKIAGVMAAGGLQILDAQIVTRKDG
                     VVVDTFQVADPDYQGAPPADRCESIGATITEVLTGRQSIDAVMRRGARLNLGRSLPAH
                     RQPAEVRIDNETSDRFTILDVFADDRQGLLYIITNAIFQLGLSVHASRISTRLD"
     gene            complement(2560..2898)
                     /locus_tag="PK063_08400"
     CDS             complement(2560..2898)
                     /locus_tag="PK063_08400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HMZ97109.1"
                     /translation="MKLIEAIVKPFKLDEVKDALLEIGIQGMTVTEVKGFGRQKGHKE
                     TYRGQEYTIEFVPKVKIEVAVNDGQVQRVLETITRAAKTGSIGDGKIFVRDLASAVRI
                     RTGETGESAL"
     gene            complement(2945..4273)
                     /locus_tag="PK063_08405"
     CDS             complement(2945..4273)
                     /locus_tag="PK063_08405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HMZ97110.1"
                     /translation="MKASAQWKTFLVGLAGALTLIGGLGAEQAWAENAPLKADSGDTA
                     WVLVSSAFVLAMLMPGLALFYGGLVRTKNVLGTIMQSIMILSVVSLLWILFGYSLAFG
                     PDKGGVIGGLDWIGLSGVGSQPHAVYAPTIPHQAFMLFQLMFAAIAPALITGAFAERK
                     RFTSVVLFAAMWSVLVYVPLAHWIWGGGWLAQLGALDFAGGAVIHISSGAAALICAIV
                     LGKRRGYGTDYMAPHNLPMTLLGTGFLWFGWFGFNGGSALGANGVAVSAIIASHAAAC
                     MGAISWCGAEWMHRGKPTVLGLASGAVAGLATVTPAAGYISPLWAILIGLVAGMSCYA
                     AIVWKGRFGYDDSLDVVGIHGVGGVIGVLATGLCASKVVNPGGADGLFFGNPGLFGVQ
                     LLVVVVTTVFSLVGTFAILKLVDAMTGLRVSPEEEATGLDLSQHNERAYS"
     gene            complement(4351..5229)
                     /locus_tag="PK063_08410"
     CDS             complement(4351..5229)
                     /locus_tag="PK063_08410"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97111.1"
                     /translation="MNMLVGRKARAWVLGLALMAGGGGGALVEAQAATTDDLMDTTKH
                     PVSVTMAMQADSFFGFNPSIYGTYGLTDNIALAFNFTYWTMISGVGVHDNAPWLETDV
                     GLNFTFLEKRLSVTPMIGFVHGSLLSSRGGFFPNGGGSVNERTTAFEGAVPNIIANYI
                     DNRFEGEFYMGYYKAIRSEGGSGGGGAIGCGNPGGTNCLGPIQGGGRGTWDFLHYWVS
                     AGVRVNSMWSMGAHYEHLLTTRDSSAPGAAQDYYRWIGPYVEMKLPGNMAFRFTVGKD
                     LTDNQDFYKLKFTKTF"
     gene            complement(5364..7136)
                     /locus_tag="PK063_08415"
     CDS             complement(5364..7136)
                     /locus_tag="PK063_08415"
                     /EC_number="6.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD+ synthase"
                     /protein_id="HMZ97112.1"
                     /translation="MMRVLRVAMAQINPTVGDIVGNTALIKTWINDARRAKADIVAFP
                     ELAITGYPPEDLLFKPRFIEDTQRALKAVAAEAHGLVVVVGYVGREATGVTPSEAEAV
                     SPAGRHDLYNAAAVLCERRLVANYCKRLLPNYGVFDESRYFRPGTRLPLLVLNGTTIG
                     VNICEDIWFPEGPTRAQAAAGAEVIVNINASPFHVGKSRLREQVLATRARENRVMVTY
                     TNTVGGQDELVFDGRSVIVDHTGEVVARGKSFEQDLLIADLDVAAVGRARQGERRARP
                     LPPRVAALVDRVAVRVPARKSSSIAVPAMESPLDRLEEAYRALVLGVRDYVQKNGFKR
                     VVIGLSGGIDSALTAVIAVDAVGADNVLGVFMPSPYTSRASREDVADLAQRLRIQVDT
                     LSITTTFKSYLRALSKPFSGHRPDTTEENLQARIRGNLLMAYSNKFGHLVLTTGNKSE
                     MSVGYATLYGDMAGGFAVIKDVPKTMVYELSQLRNLNGLEPVIPKRVLERPPTAELRP
                     DQKDEDSLPPYSVLDPILKAYVEEDRALEDIVAMGFERETVARVMIMVDRSEYKRRQA
                     PLGIKITHRAFGKDRRMPITNGYR"
     gene            7523..8413
                     /locus_tag="PK063_08420"
     CDS             7523..8413
                     /locus_tag="PK063_08420"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97113.1"
                     /translation="MSRACEPMRLRKSWLLVLTCLLLVACSATSPLIPVGEGPLGTVS
                     LERLASRGTTARYGSPQSAFQASHPASVSASVISRLLSGLSVSGLERPGAALRQERYP
                     LFTQEEMEFFSPLIVKALSQAGPDQRVRFTLQDDGLITQGTLYLHKTTLRVSLSHYRA
                     SQGQSDTRPTALTLSFTPSEALVRDDVPQSWMIIEPEQPRIAVSLEVLNELRAAVSAP
                     TANKPVAVIPVAPAPAASEQTNLQQELQATKDVVVKQAQELQQLKTELESLRRELAER
                     DSTTPKAKPKAAPRKTVPTP"
     gene            complement(8688..9062)
                     /locus_tag="PK063_08425"
     CDS             complement(8688..9062)
                     /locus_tag="PK063_08425"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97114.1"
                     /translation="MKAMRKAWCIACLVTVAACTTGQYQPLNGADKDEVEQLRENVYR
                     VEYRVSSFTSQEQLDSYLRRRCAELTLREGYNFFHLAQRADVLALSRRTSMTVTMYKG
                     KKPSGADDVYDAKEVLAGPLAQ"
     gene            complement(9524..10783)
                     /locus_tag="PK063_08430"
     CDS             complement(9524..10783)
                     /locus_tag="PK063_08430"
                     /inference="COORDINATES: protein motif:HMM:NF024883.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF and ANTAR domain-containing protein"
                     /protein_id="HMZ97115.1"
                     /translation="MASKRTVPQLEQALREKTREVDVLHRISESISSTLDLESVLRHI
                     VDVVVEATKADACLLYLLSDNRDELILRASKNPHPKLIGRITIGLGEGITGWVARERT
                     RVVIPNSASDDSRFKFFHNLPEDRYQAFVSVPITTKQEVVGVINVQHKRSRRYRPDEL
                     ALLSTIATQVGGAIENARLYDQMTRKALQLDTLSQVSETVSSNRLMEDVLQLIVTMTA
                     QMMGSKICSIILLDQPTGELRIAATQSLSEQYRRKPNVKIGQSISGRAVQDRRPIIVP
                     DVTKEGSYMYPDMAAKEGLCSLLCVPMLVREKAIGVINTYTSKPHTFTSEDVKLMQAI
                     ANQAAISIEHTTLLEKSFEMQEALQVRKLLDRAKGYLMRSKRLSEEDAFKLIQRQSMD
                     LRKSMREIAEAILLAGEIEDRADKNRG"
     gene            complement(10791..11948)
                     /gene="aroB"
                     /locus_tag="PK063_08435"
     CDS             complement(10791..11948)
                     /gene="aroB"
                     /locus_tag="PK063_08435"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: protein motif:HMM:TIGR01357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HMZ97116.1"
                     /translation="MATSTPDMPRDTIHLELGARSYDIQIGRGLLKEIGVEMTRLRCA
                     GKVGVVTDRNLAGHYLKPVIRVLKAAGYTVVPIVLPPGERTKTLRSIGTVMDALVNAR
                     FERSSTLLALGGGVIGDITGFAAAIYQRGIPFVQVPTSLVAQVDSSVGGKTGVDHPKG
                     KNLIGAFNQPRAVLIDPATLRTLPEREWIAGLAEVIKYGVIEDESFFKYLEEHIAPIL
                     MLSDAPVAHIVKRSCEIKAQVVSEDEREADRRRILNFGHTIGHALESLGGYRGLIHGE
                     AVAVGMVYEADLARHLGYCHEDVVTRLRALVAAAGLPVRVPKVPFRALWDAMQQDKKV
                     SAGTVYCVVPERIGSVRIVPLAKEQTRAWYDTVSSDNTRSRQFIPNNKRRR"
     gene            complement(12218..14167)
                     /gene="pilQ"
                     /locus_tag="PK063_08440"
     CDS             complement(12218..14167)
                     /gene="pilQ"
                     /locus_tag="PK063_08440"
                     /inference="COORDINATES: protein motif:HMM:TIGR02515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009297 - pilus assembly [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus secretin PilQ"
                     /protein_id="HMZ97117.1"
                     /translation="MKQTQVGVHPLLSVTVMAGLLGLAGYVQAAAPGETTGLAGFTQA
                     TDQATSAEFTAAKEEHSTGATPTATLLTSVEAKPEGGRVALILTGNGVFDHTVKMVGD
                     RRMVLDMPHIQSQGRQTQLAVGHALLSKVRFGYHADKVRLVLDLAQPAEHSVTSVDGR
                     LVLMLEPKSVPTNDVKLAESEASPSAEQTAARSMVVSHKTPHALFRVQPIQLTAESVQ
                     KEDRKPETNEVVNGSSRFVGRRISLDFQQADISNVLRLIAEVSGFNIVVGEGVKNKVT
                     MKLANVPWDQALDMLLKMNALGMIRQGNIVWVDTLQNIAKQQDEEARAKDSKAKAEPI
                     VTRVFYIRNLNATEVQTSLRQNLSPRGTMTVSAASNALIISDTESKLEVLRQLLDGVD
                     LEVPQVQIEARIVQADTTYTRSLGVQWGIQNVNQLGASSGTSAFKTGTTGAFGAQVSD
                     FLINLPANPGLPSVPGAGFSIGKTDGAMLDVRLSAGELLGLTKVIAAPKITTLDKRDA
                     KIAQGESIPFQTTSLQGTQTTFVDANLELNVTPQITSRDPKEIGKQILMKVRATRNAV
                     GARSNPAGPSIDRREATTQVLVRDGETMVIGGVFVDTQSNNVAGIPYLSRVPVLGWLF
                     KNKTENVSKQELLIFLTPTIVRSAT"
     gene            complement(14164..14763)
                     /locus_tag="PK063_08445"
     CDS             complement(14164..14763)
                     /locus_tag="PK063_08445"
                     /inference="COORDINATES: protein motif:HMM:NF016254.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilP"
                     /protein_id="HMZ97118.1"
                     /translation="MNTRTCWKMSIGAAVLVIGGTAMPVESKSLPHLRQIASMRPADS
                     LKVMPLPEGQKPAPAMESPAPRVEASVSQPGDSLSMEFSGTSYDPSGRRDPFLPMVQL
                     GQQVEQDASLPPLQRVGLTELSLIGVLWGNYGYTAMVQTPDGKGYSIRRGTRIGPNNG
                     VVSSITERGIIVQERFTDVYGNKQEREYVKLLHPKEGTE"
     gene            complement(14805..15428)
                     /gene="pilO"
                     /locus_tag="PK063_08450"
     CDS             complement(14805..15428)
                     /gene="pilO"
                     /locus_tag="PK063_08450"
                     /inference="COORDINATES: protein motif:HMM:NF016253.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0043107 - type IV pilus-dependent motility
                     [Evidence IEA];
                     GO_process: GO:0043683 - type IV pilus assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HMZ97119.1"
                     /translation="MSLNAISLDSLRSIPTGQKVALLGLLVAGILVGFYFYVVDPKTV
                     ELEAVQGQVAQLDTEIQNLTLKVKHLDELVAANKQLEIELAAKKERLPPEEEAVMLLK
                     QVSDLGLRLGLDVKLWKPGTQAEDPSKLFIRMPINVEVAGGYHTAAIFFDRISKLSRI
                     VTVQDVRIGAARVDQGRVVTQTVFDLVAYAAPQEKKPAAPVPAAKPK"
     gene            complement(15430..15984)
                     /locus_tag="PK063_08455"
     CDS             complement(15430..15984)
                     /locus_tag="PK063_08455"
                     /inference="COORDINATES: protein motif:HMM:NF016992.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HMZ97120.1"
                     /translation="MIRINLLATGPRSRKAKPQWDVRAEALIGVGVLLITLTGCWFYA
                     SSLDEDIQAKQSEKQLKDKQVAQLKEQVKAVQDFEDKKKQLEAKNRIIDQLEKSRTGP
                     VKVLDHVSQSLNPLKVWLVRLNLKGNSVELEGRALTNDDVVEFVNNLRRTDQFGAIKL
                     MESRAGLDNKMNTYQFRLDLSMKG"
     gene            complement(15981..17078)
                     /gene="pilM"
                     /locus_tag="PK063_08460"
     CDS             complement(15981..17078)
                     /gene="pilM"
                     /locus_tag="PK063_08460"
                     /inference="COORDINATES: protein motif:HMM:TIGR01175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009297 - pilus assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus assembly protein PilM"
                     /protein_id="HMZ97121.1"
                     /translation="MLASLKHLTDMDFLSMFSPQKQLLGLDIGSSSIKLVQIKEHRGR
                     YTLQKFGVKELEPEVIVDGTVMDEGRVVSAIKELLAEHNVKLKQVAVSISGHAVIVKK
                     ITLPPMPDEELDAQVKLAAEQYIPFDINEVNLDFYVLPPSENPDEQTEMQIVLVAAKK
                     DKINELTELVKAAGLVPIVMDVDAFAVENMYGVTSPSTQEDTTILVNIGASVMNVNIV
                     GGGVSLFTRDIPLGGNRYSEAVQREMGVSYEEAEQLKKNDGDDDHTLAAVMESVNAEV
                     ASEIARTIDYFKTTSSESEIARVLLFGGGAKVKGLAQQLRDRMHVDVEIANPFNEIDT
                     SQCNVDPEQLAEMGSLAAVGVGLALRTVGDR"
     gene            complement(17092..17307)
                     /locus_tag="PK063_08465"
     CDS             complement(17092..17307)
                     /locus_tag="PK063_08465"
                     /inference="COORDINATES: protein motif:HMM:NF024803.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HMZ97122.1"
                     /translation="MKKVNDGQKKKLYKTNEVCEMFDISRATLFRWEREGLITGPPRD
                     WRNWRLYTAENVEQIKHVMGGGRKDVA"
     gene            complement(17443..18309)
                     /gene="rapZ"
                     /locus_tag="PK063_08470"
     CDS             complement(17443..18309)
                     /gene="rapZ"
                     /locus_tag="PK063_08470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HMZ97123.1"
                     /translation="MAALNLVVISGLSGSGKSHALKAFEDAGYFCVDNLPPALLPTFV
                     ELCHQQGGEIKNVALGIDIRERVFFGDLAKVLAELKSQGHALQLVFLEAREEVLVRRF
                     SESRRPHPLLPHMPVVEGVRFERERLSELRKHADRVIDTSTLTVHELRDLLIRQFRQE
                     TTARRMTISLVTFGYKFGVPYDIDLLFDVRFIRNPFFVPELKALTGEDLRVQQYVFGD
                     ETAGQFLEHLQKLFAFLIPLYERDQRSYLSIGIGCTGGRHRSVTIALRLQAQFAALGY
                     DVSVTNRDLQKS"
     gene            complement(18296..18847)
                     /gene="raiA"
                     /locus_tag="PK063_08475"
     CDS             complement(18296..18847)
                     /gene="raiA"
                     /locus_tag="PK063_08475"
                     /inference="COORDINATES: protein motif:HMM:TIGR00741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_component: GO:0022626 - cytosolic ribosome [Evidence
                     IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HMZ97124.1"
                     /translation="MRLMITGRHVAVTPALREYIELRMERLDRYGLKLGTLQILLSVE
                     KFHHVAEVVGVVQGRRLQAKTTTEEMYASIDEVVDKLGAQLRKLKERKVNHKFGDQPR
                     VRAVARKTPRAKDDGMEVVRPRLEALTIEEAVETLNGEKLPLLMFVNALSGSIQVLQR
                     LPNGRLSLIDPASDRARVAHGRA"
     gene            complement(18954..20471)
                     /gene="rpoN"
                     /locus_tag="PK063_08480"
     CDS             complement(18954..20471)
                     /gene="rpoN"
                     /locus_tag="PK063_08480"
                     /inference="COORDINATES: protein motif:HMM:NF009118.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HMZ97125.1"
                     /translation="MKLRLDLRLSQKLIMTPQLQQAIKLLQLSRLELQQSLQQHLMEN
                     PLLDELVAETEESEETAATEREQPDTATTVAAETRGEGDDKPAESGENAEEFSASTWE
                     DYFDTDMRRGETEYSSSSKEEFPSYEQTVAKSTSLEDHLVWQLSLSGLSDREKAIGRL
                     IIGNLDDDGYLRMTLDELVAGSEYSVAEAESVLKDVQGFDPNGVAARDLSECLLLQLK
                     FLGRSQLGSLGSRPGVLKGSVLEAIVLHHLKDLEKKQYNRIAKALNISMDDVFEATRI
                     IEGLEPKPGRPFSNTQNYAIVPDVFVVKNEGEWEVLLNDDGLPRMRISPYYKQLMSSG
                     QSGSAETKAYLDDKLRAAQWVIRSIEQRNKTIVKVVSSIVKFQEGFFEHGIQHLKPLV
                     LKQVAEDIGMHESTISRVTANKYMYCPQGMLELKFFFNAGLQRADQPTDMLSSLTVRE
                     MIRQMVAAEDARKPLKDEEIAARLRTQQVLIARRTVAKYRAEDNIPSATQRRKFF"
     gene            complement(20490..21203)
                     /gene="lptB"
                     /locus_tag="PK063_08485"
     CDS             complement(20490..21203)
                     /gene="lptB"
                     /locus_tag="PK063_08485"
                     /EC_number="7.5.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015920 - lipopolysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter ATP-binding protein"
                     /protein_id="HMZ97126.1"
                     /translation="MAASGLVKSFRGRKVVKGVSLDVQAGEVVGLLGPNGAGKTTIFD
                     MMVGLCQPDEGQIALSGNDITDLPMYKRARRGIGYLPQESSVFRRLSVEHNILAILEM
                     LGYSRSERMERVETLLKELDLVHIRKSKAYALSGGERRRLEITRALATSPLFMLLDEP
                     FAGIDPIAVADIQQIIIRLKQRHIGVLITDHNVRETLSITDRAYIINEGTILEAGPPG
                     VIEKSEMARAVYLGEGFRL"
     gene            complement(21275..21868)
                     /locus_tag="PK063_08490"
     CDS             complement(21275..21868)
                     /locus_tag="PK063_08490"
                     /inference="COORDINATES: protein motif:HMM:NF015901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LptA/OstA family protein"
                     /protein_id="HMZ97127.1"
                     /translation="MSCLLLSGEAVLSTHNAYAIETRGTKEPPASSAPTTITSRTMTV
                     NNQENTAIFDGAVVLTRGPLVVHSDHMVVSFHPSRNGADGKESGGPTKSKNLTNPTTA
                     ESKERDAAPAVSERSIRMVEATGRVNIKKEDGQATCQKAVYYEEQKKIVLTGEPVAWQ
                     KGTRVSGKRIIMFLDEDRSVVEGDSQVVIEGEGGGKR"
     gene            complement(21849..22421)
                     /gene="lptC"
                     /locus_tag="PK063_08495"
     CDS             complement(21849..22421)
                     /gene="lptC"
                     /locus_tag="PK063_08495"
                     /inference="COORDINATES: protein motif:HMM:TIGR04409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015920 - lipopolysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter periplasmic protein
                     LptC"
                     /protein_id="HMZ97128.1"
                     /translation="MWERWVRRGLLALSVVLAAFLGYLLITRSNPSSSSRSVAPVEAE
                     SADAHIQDFTFTQTKGDLVQWKVQAEQARLYEKESRAILSNVQITMYGAQGKELSLSG
                     DEGTLDTQTKNFQLSNRSTPIVVETQSGYTIQTNHLVWTDARHEIQTPDHVTILGHGL
                     QVTGRGLLGKMDTEEFKILDDVHVDVVPAS"
     gene            complement(22711..23058)
                     /gene="rplQ"
                     /locus_tag="PK063_08500"
                     /pseudo
     CDS             complement(22711..23058)
                     /gene="rplQ"
                     /locus_tag="PK063_08500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007085264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005762 - mitochondrial large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
     gene            complement(23077..24078)
                     /locus_tag="PK063_08505"
     CDS             complement(23077..24078)
                     /locus_tag="PK063_08505"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HMZ97129.1"
                     /translation="MIKAMKDFQIPMRVEVDKDTLSPTFGRFTTEAFERGFGTTVGNS
                     LRRVLLSSLTGAAVTTVKIEGVLHEFSTIPGVTEDVTSIILNVKSLRLALQGDKPKTI
                     RLKKKGPGEAKGSDITHDGDVTILTPDLHIATLDKDAALDMEMTIKHGRGFVPAERNK
                     EEGLPIGVIAIDSIFSPIKRVNFHVENARVGRMTDYDKLTLEIWTDGTISPRDALSNA
                     AGILREHLDIFINPEERSDAKPSAGSEDLSDEVNKNLYRSVNELELSVRAANCLKNAN
                     IKTIADLVQKTEAEMLKTKNFGKKSLNEIKEILTEMGLSLGMKVDALPSGDAGVRSE"
     gene            complement(24163..24789)
                     /gene="rpsD"
                     /locus_tag="PK063_08510"
     CDS             complement(24163..24789)
                     /gene="rpsD"
                     /locus_tag="PK063_08510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016666076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HMZ97130.1"
                     /translation="MAKYSGPVCRLCRREGEKLFLKGSRCMTEKCAIERRSYPPGQHG
                     QARQRTSDYSLQLREKQKLKRIYGLQECQFRGIFERAERQAGVTGDTLLRLLECRLDN
                     VVYRLGFGASRKEARQLVNHGHLMINGRKVKAPGALVKAGDSIEVRQKSRELIPIQGA
                     LAAVDGRGIPEWLELDRAAYKGTIRSLPTKEHIVLPVNEQMVVELYSR"
     gene            complement(24871..25254)
                     /gene="rpsK"
                     /locus_tag="PK063_08515"
     CDS             complement(24871..25254)
                     /gene="rpsK"
                     /locus_tag="PK063_08515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006831904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HMZ97131.1"
                     /translation="MSVKKGKKKERKIVQSGVAHVQASFNNTIVTITDMSGNTVVWAS
                     SGNQGFKGSRKSTPFAAQRAGEAAARKAMENGMRQVDVYVNGPGAGRESAIRSLQSAG
                     LRINLIRDVTPIPHNGCRPPKRRRV"
     gene            complement(25296..25685)
                     /gene="rpsM"
                     /locus_tag="PK063_08520"
     CDS             complement(25296..25685)
                     /gene="rpsM"
                     /locus_tag="PK063_08520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HMZ97132.1"
                     /translation="MARIAGVDLPKDKRIEIGLTYVFGIGRVAAQAILKKAGVDGAIR
                     VKDVSEDKIVKIREVIERDYRVEGDLRKEVSMNIKRLVDTGTFRGLRHRKGLPVRGQR
                     TKTNARTRKGRRSGVGSKPQKPAGSRA"
     gene            complement(25820..25933)
                     /gene="rpmJ"
                     /locus_tag="PK063_08525"
     CDS             complement(25820..25933)
                     /gene="rpmJ"
                     /locus_tag="PK063_08525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HMZ97133.1"
                     /translation="MKVKSSVKPICAKCKVVRRRGVVRVLCANPRHKQRQG"
     gene            complement(25952..26170)
                     /gene="infA"
                     /locus_tag="PK063_08530"
     CDS             complement(25952..26170)
                     /gene="infA"
                     /locus_tag="PK063_08530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HMZ97134.1"
                     /translation="MPKEDVIEVTGTVAETLPNAMFRVELENGHRILAHISGKMRMHF
                     IRILPGDKVTIQLSPYDLTRGRITYRFK"
     gene            complement(26192..26947)
                     /gene="map"
                     /locus_tag="PK063_08535"
     CDS             complement(26192..26947)
                     /gene="map"
                     /locus_tag="PK063_08535"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HMZ97135.1"
                     /translation="MIVFKTPDEVTLMAQASRVVAEVLALLKGKVEPGITTEDLDRIA
                     EEAIRGRGAIPAFKGYRNYPKTLCASINEQVVHGIPSKRKLKEGDIIGLDLGAIVSGF
                     YGDSAVTVPVGSASEEALRLIQVTEEAMYQGIAKAVVGNRLSDVSHAIQTHVEQAGFA
                     VVTEFVGHGIGRQLHEEPQVPNYGKPGQGPRLQVGMVLAIEPMVNMGGSAVRILEDRW
                     TAVTQDGRWSAHFEHTIAIQPSGPAKILSQLSH"
     gene            complement(26944..27600)
                     /locus_tag="PK063_08540"
     CDS             complement(26944..27600)
                     /locus_tag="PK063_08540"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HMZ97136.1"
                     /translation="MRLVFLGAPGVGKGTQADRVTAQFGWPKISTGDLLREAVRNQTA
                     LGIEAKKSMDAGKLVPDSVVIGMVRETLAAPSCQKGFVLDGFPRTVPQAEELQALLTG
                     RNLKLDRVINFRVSRHDVVTRLSGRRSCPKCQSVFHIAFAPPKIEGQCDRCGASLIQR
                     SDDKPETIEARLKVYDEQTAPLIAYYQAKNLLSDLDGSGEMAAVYTRLSALLLGLGAQ
                     "
     gene            complement(27610..28923)
                     /gene="secY"
                     /locus_tag="PK063_08545"
     CDS             complement(27610..28923)
                     /gene="secY"
                     /locus_tag="PK063_08545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HMZ97137.1"
                     /translation="MFERLLTSFQNIFKIPELRTRVLFTLGMLIVYRVGAHIPTPGIN
                     GEALSEFLQKQGGALLGFLDIFSGGSLSRLTIFALGIMPYISASIILQLLTVVIPHLS
                     KLAKEGERGRKKIIQYTRFGTIVIALIQGFGIAVGLEQMNQGAFVLSPGWGFRFMTVI
                     TLCAGTGFLMWLGEQITERGIGNGISLIIFAGIVARLPAAVAQTFDLYKVGQLSFPLL
                     IVLAVVMFGVVAAIVFLESGRRKVPVQYAKRVIGRRVYGGQSTHIPLKINTAGVIPPI
                     FASSIIAFPATIAGFFETPWIKAIGSQLAPGSLLYTLMYVGLIVFFCFFYTAVVMNPV
                     DMADNLKKYGGFVPGIRPGQRTSDYIYSVLTKITFAGAIYLAIVCVIPEFLIYKLNMP
                     FYFGGTSLLIVIGVGLDTAQQIESHLLNRNYDGFLQKGKLRGRTS"
     gene            complement(28916..29365)
                     /gene="rplO"
                     /locus_tag="PK063_08550"
     CDS             complement(28916..29365)
                     /gene="rplO"
                     /locus_tag="PK063_08550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HMZ97138.1"
                     /translation="MKLHDLAPSRGAKHKPKRIGRGPGSGHGKTATKGHKGLKARSGG
                     GKRPGFEGGQMPLIRRVPKYGFTNQFRTEYTIINLKSLAGLETTEAITPQLLMNEGLV
                     RRKGELIKILAQGELTKPLVVQAHKFSKSAEAKIQAAGGRAEVIPCV"
     gene            complement(29362..29571)
                     /gene="rpmD"
                     /locus_tag="PK063_08555"
     CDS             complement(29362..29571)
                     /gene="rpmD"
                     /locus_tag="PK063_08555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007861725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HMZ97139.1"
                     /translation="MATEKKTTTAQASLRITLKRSPIGTPYKHRLVLRGLGLRKLNAT
                     VLRPATDQVKGMIAKVGYLLEVSPQ"
     gene            complement(29579..30070)
                     /gene="rpsE"
                     /locus_tag="PK063_08560"
     CDS             complement(29579..30070)
                     /gene="rpsE"
                     /locus_tag="PK063_08560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000312 - plastid small ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HMZ97140.1"
                     /translation="MRVNPEELSLKDKVVFINRVAKVVKGGKRFNFCALVVVGDGQGY
                     VGVGKGKAAEVPVAISKAVEQAKKHLVRVPIKGGTIPHEVHGLFGAEHVLLKPAADGT
                     GIIAGGAVRAVVELAGAHNIIAKTLGRGNPFNAVRATLNGLQQLCDPQEIMRLRRAVG
                     SEA"
     gene            complement(30139..30504)
                     /gene="rplR"
                     /locus_tag="PK063_08565"
     CDS             complement(30139..30504)
                     /gene="rplR"
                     /locus_tag="PK063_08565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003448744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HMZ97141.1"
                     /translation="MNTQEKNRKLARRKQRVRKSVVGTSDRPRLNVFRSRSHIYAQII
                     DDLRGHTVAAASTLDESLRKAVKSTGSIEGAKAVGKLIAERAKAANVSMVVFDRGGRQ
                     YHGRVKALADASREGGLQF"
     gene            complement(30514..31050)
                     /gene="rplF"
                     /locus_tag="PK063_08570"
     CDS             complement(30514..31050)
                     /gene="rplF"
                     /locus_tag="PK063_08570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HMZ97142.1"
                     /translation="MSRIGRKPIAVPSGVDVKVAGRLVSVKGPMGKLDWKLTDGLSVA
                     VADGQLVVNRSGDAREIRAMHGLVRAELSNIIQGVTKGYEKSLEITGVGYKAQLQGRE
                     MSFNVGYINPVTYTVPQGIDVKVDKQTLISIKGIDKRLVGQVAANIRSIKPPDVYKQK
                     GIRYAGEVLRKKAGKTGK"
     gene            complement(31108..31503)
                     /gene="rpsH"
                     /locus_tag="PK063_08575"
     CDS             complement(31108..31503)
                     /gene="rpsH"
                     /locus_tag="PK063_08575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HMZ97143.1"
                     /translation="MITDPIADLLVRLGNAARRRQDVVKVPVSKVKRQILNILGKEGF
                     ILGYGETQEDGHPIFSVQLRYVEEARPMITGMRRISKPGRRVYVGRDDVPKVRNGIGV
                     AVISTSKGLMTDSDSRRAGLGGEVLCAVW"
     gene            complement(31549..31734)
                     /locus_tag="PK063_08580"
     CDS             complement(31549..31734)
                     /locus_tag="PK063_08580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008752089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HMZ97144.1"
                     /translation="MSRLALKNKAAVKSKFSCRDYHRCGLCGRVRGFLRRFRMCRICF
                     RSLSLKGEIPGVRKSSW"
     gene            complement(31796..32326)
                     /gene="rplE"
                     /locus_tag="PK063_08585"
     CDS             complement(31796..32326)
                     /gene="rplE"
                     /locus_tag="PK063_08585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HMZ97145.1"
                     /translation="MRETYRDQVIPALMKEFGYGNLMQVPRLERIVLNVGMGEAIQNV
                     KLLESAASELGIITGQKPVTTRAKKAIAGFKLRQGMPIGAKVTLRSRRMWEFLDRLIS
                     LALPRIRDFRGISPKAFDGRGNYTLGLKEQLIFPEIEYDSVASIHGMDITIVTTARTN
                     DEGKALLKHLGMPFRA"
     gene            complement(32470..32796)
                     /gene="rplX"
                     /locus_tag="PK063_08590"
     CDS             complement(32470..32796)
                     /gene="rplX"
                     /locus_tag="PK063_08590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HMZ97146.1"
                     /translation="MARIKTKIRKGDTVVVMTGRERGKSGKVLSVDTVTGKVLVEKLN
                     MIKRHTKPNQKLRQGGILEREAPLAISNVMFLCPVTKKPTRLGIKRQEDGRRTRLSKK
                     SKETVE"
     gene            complement(32823..33191)
                     /gene="rplN"
                     /locus_tag="PK063_08595"
     CDS             complement(32823..33191)
                     /gene="rplN"
                     /locus_tag="PK063_08595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007073026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HMZ97147.1"
                     /translation="MIQNYTYMDVADNSGAKQVMCFHVLGGTRRRYGSLGDIVVVAVK
                     EAIPQAGVKKGDVSRAVIVRTTKEVRRDDGSYIKFDRNACVLINAQGEPVGTRIFGPV
                     ARELRWKKFMKIISLAPEVL"
     gene            complement(33253..33522)
                     /gene="rpsQ"
                     /locus_tag="PK063_08600"
     CDS             complement(33253..33522)
                     /gene="rpsQ"
                     /locus_tag="PK063_08600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003022794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HMZ97148.1"
                     /translation="MKEGQQHRREWYGNVVSNKMNKTVVVAVERSVIHPIYKKVLRRV
                     TKLKAHDEGNVCKVGDRVQLSETRPISKDKHWRVVRVMVKGQPEK"
     gene            complement(33537..33758)
                     /gene="rpmC"
                     /locus_tag="PK063_08605"
     CDS             complement(33537..33758)
                     /gene="rpmC"
                     /locus_tag="PK063_08605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HMZ97149.1"
                     /translation="MDVKDLSGLSLEELAAKEKQLRQELFNFRFQLGIGRLENPMQVR
                     STKRDIARLKTVRRQLELLQTQAGQSVGK"
     gene            complement(33787..34203)
                     /gene="rplP"
                     /locus_tag="PK063_08610"
     CDS             complement(33787..34203)
                     /gene="rplP"
                     /locus_tag="PK063_08610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HMZ97150.1"
                     /translation="MLAPKKVKFRKMQKGRMRGKAYRGGAITLGEFGLKALEPGWITS
                     RQIEAARIAITRFVKRGGQVWTRIFPDKPITKKPAETRMGKGKGNPEYWVAVVKPGRI
                     MYEMGGVAPDVAKQALKLASYKLPIATKFVVRGEFQ"
     gene            complement(34231..34899)
                     /gene="rpsC"
                     /locus_tag="PK063_08615"
     CDS             complement(34231..34899)
                     /gene="rpsC"
                     /locus_tag="PK063_08615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000312 - plastid small ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HMZ97151.1"
                     /translation="MGQKTHPIGYRIGYNYTWSSRWYADKDYARLLHQDIKIRKMVKA
                     KLYHAGVAKVEIERSGDQTRVIIHTARPGIIIGRKGAEVDKLKAALEKEYSGQAYITV
                     KEIKKPELDAQLVSENVATQLEKRVAFRRAMKRSVQSALRLGAQGIKIMVAGRLGGAE
                     IARTEWYREGRVPLHTLRAEVDYGFAEAHTTMGQIGVKTWIYKGELLPALQLKPDSTL
                     GRLG"
     gene            complement(34932..35285)
                     /gene="rplV"
                     /locus_tag="PK063_08620"
     CDS             complement(34932..35285)
                     /gene="rplV"
                     /locus_tag="PK063_08620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HMZ97152.1"
                     /translation="MAEAKANLRFVRVTPRKARVVIDMIRGQQVPMALAMLRHTPKHA
                     ARVIEKLLRSAVANAEQKELGDSDEMWVSQAVVNCGPIYKRFRARSMGRANSIQKRTS
                     HITIAVAAPNAAHSS"
     gene            complement(35330..35617)
                     /gene="rpsS"
                     /locus_tag="PK063_08625"
     CDS             complement(35330..35617)
                     /gene="rpsS"
                     /locus_tag="PK063_08625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HMZ97153.1"
                     /translation="MPRSITKGPFVDDHLIKKVEQMNQTKDRKLIKTWSRRSTVIPDM
                     IGHTFAVHNGKKFIPVFVTENMVGHKLGEFAPTRFFKGHGQAKTEKAVALK"
     gene            complement(35627..36454)
                     /gene="rplB"
                     /locus_tag="PK063_08630"
     CDS             complement(35627..36454)
                     /gene="rplB"
                     /locus_tag="PK063_08630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HMZ97154.1"
                     /translation="MALKVYKPTTPGRRGMTAIQGEKLTKKKPEKSLTGFHLRTGGRN
                     NDGRLTIRFRGGGHKRLYRQIDFRRDKAGVPAKVAAIEYDPNRSSRIALLHYLDGEKR
                     YILAPVGLSVGDMVQSGEGAEVRPGNALPLVNMPLGTTIHNIELKPGKGGQLIRSAGG
                     SAQVMGRDGAYVQIRLKSGEMRKVLSTCMATVGQVGNVDHENVVVGKAGRTRWKGKRP
                     HVRGVVMNPVDHPHGGGEGKSGQGNPHPVSPWGTPAKGYKTRKNKSTDKFIIARRKK"
     gene            complement(36487..36780)
                     /locus_tag="PK063_08635"
     CDS             complement(36487..36780)
                     /locus_tag="PK063_08635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HMZ97155.1"
                     /translation="MKGDLHQVLIQPLLTEKITALREQSNTVGFLVHPDANKIQIKQA
                     VESLLKVKVSRVNVVNIRGKIKRLGRFVGKRSDWKKAFVTLKEGEKLELYETV"
     gene            complement(36777..37400)
                     /gene="rplD"
                     /locus_tag="PK063_08640"
     CDS             complement(36777..37400)
                     /gene="rplD"
                     /locus_tag="PK063_08640"
                     /inference="COORDINATES: protein motif:HMM:NF012782.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HMZ97156.1"
                     /translation="MPIVDVVDSKKKKVGSVDLPDEVFGCKPHGSLVHEAVVMQRACD
                     RQGTASTLRRGEVSGSGKKPWKQKHTGRARAGSLRSPVWRHGGTVFGPKPRSYAFGMP
                     KKKYRAALQSVLSAKLSEGNVVVVSELSIAEAKTKLLANVLAQLGISGTALLVVADPN
                     SHVMQAGKNLSSVTVLRPEELNVYDVLRCHSLVIPQGELERVKEVWS"
     gene            complement(37404..38024)
                     /gene="rplC"
                     /locus_tag="PK063_08645"
     CDS             complement(37404..38024)
                     /gene="rplC"
                     /locus_tag="PK063_08645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HMZ97157.1"
                     /translation="MTNGLLGKKLGMTQIYDESVLEPVTVIEAGPCRVVAIKTKERDG
                     YEAVQLSFGEVKESRLSGGELGHLKKHQAPPSRWLREFPKTGEVAVGATVKVDMFKKG
                     DWVDVVGVSKGKGFQGVVRRHNYAGGPETHGSMFHRAPGSIGASSYPSRVWKNKALPG
                     HMGDERVTVQRLKVIDARPDENLLFVRGAVPGGANGLLVVRKSKKS"
     gene            complement(38066..38377)
                     /gene="rpsJ"
                     /locus_tag="PK063_08650"
     CDS             complement(38066..38377)
                     /gene="rpsJ"
                     /locus_tag="PK063_08650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018003271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HMZ97158.1"
                     /translation="MKVDQRIRIRLRGFDYRVLDQSVVEIVETVRRSGARVVGPIPLP
                     TRIEKFTVQRSTHVDKKSREQFEIRTHKRLLDIMEPTPETMDSLMKLNLAAGVDVEIK
                     L"
     gene            complement(38417..>38592)
                     /gene="tuf"
                     /locus_tag="PK063_08655"
     CDS             complement(38417..>38592)
                     /gene="tuf"
                     /locus_tag="PK063_08655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012147227.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HMZ97159.1"
                     /translation="VTGIVTLAAGVEMVMPGDNVTVTGELISPIAMDQGLRFAVREGG
                     KTVGSGVVTEILA"
BASE COUNT         8303 a        11903 c         9700 g         8686 t
ORIGIN      
        1 gatcgagccg ggtggaaatc cgggacgcat gcaccgacaa gcccaattga aaaatagcgt
       61 tcgtgataat gtacagcaat ccttgccgat catccgcaaa aacatcaaga atcgtaaacc
      121 ggtcggacgt ctcattatcg atacgcactt ccgccggttg acgatgggcg ggcaatgacc
      181 ggcccagatt caatcgcgcc ccgcgccgca tcaccgcatc gatcgactga cggccggtca
      241 gcacctccgt aatggtcgcg ccgatcgact cgcaccgatc cgccggcgga gcgccctgat
      301 aatcaggatc ggcgacctgg aaggtatcga cgaccacgcc gtcttttctg gtcacgatct
      361 gcgcgtccag aatctgcaag ccgccagccg ccatcacccc ggcaatcttc gaaaacaatc
      421 cgggaatcag atcattatgt gcaatcacgg catattcgca tgttcccaac ggagcattga
      481 actccgtctc cacgaccacg ccgccctcct gcagacggcg gatggcgccc aagtgggcgg
      541 caatgcgcag cggactcgta ccgtagacat accgcagggg aaactgttcg agttcggaac
      601 agatccaggt tttgtcggct ggaaggttgt gatccccctg cgactgtccc gccacgtcat
      661 cggcgatacg cgccaagcgc tgcggctcat cggccgtctc ccgctcgccc gatacttcct
      721 gcatggctcg caggtacagt tcaaccagca gcgattcttt ccatttcgtc agcacatcag
      781 ggcccacggc agcgatgtcg gcagcggtca gggccagtaa cttgcgcaac acttccggcg
      841 tgccgacttc acgcgcaaac ggcaacagca ccttttcatc atacgggtcg cggcgaaagg
      901 ccgtgtgagc catcaacaga tgccgatgga ccagcatcac caaggtacgc gtgtccggct
      961 catcgaagcc gagacgcgcg gccgtttctt ccgccaaccg ctttccaacc tcactatgat
     1021 cttcctcgtg accttttccc aggtcatgaa ggaggagcgc cagatgcagc agatccttcc
     1081 gtttgatctc tcgatagacc tcaccgagga ccccgctatg gtcggccaga gtttcggctt
     1141 tcgccaccgc gagtaaacta tgctcgtcga ccgtgtactt gtggtactga ttgaattgca
     1201 tcagtccacg cacacgtgag aacgccggca cgagtttctc caacagatgc gcccgatgca
     1261 tggcttccag ggtccgcgcc gtgcctgggc ccgccagaat cgaaaggaag gtttggcctg
     1321 cctccggcgt gtggaactgt tcgacggaca gcgtctccgc atgccggtga atgtcttcca
     1381 ggagagacgg atcgatactc aactgccgcg aacgagccag gttgaagagc gtaagcagca
     1441 atgtcggctg caccaggacc tgtgaacgca actcaaccgg aacggtcaac gcctcaccat
     1501 cgacggaaaa atattgttgg atgcgcggcg acgggagcca tcgaacgagc cgttgccaca
     1561 aggagcggcg tcggcaccgt tccacaaatc gcatcaaggc aacgtgcagc cccatcgtat
     1621 gccgatagta ttgctgcatg aattgttcga cggcgagcaa atgcggacgg tcggtgaacc
     1681 cgagatgttt cgccagccag acctgttcgt cgaaggtgag aatttcctgc gccatgccgg
     1741 ctcgaatatg gagaaaggag cggacccgca agagaaactc tctggcttcc ttgatcgagc
     1801 gataatctga ttgggagaga atcccccggt cagagagttc gcgaatggtg ggcgcctgaa
     1861 atcgcgcgga accgatccat tgcaggaggt gcaggtcgcg caagccccct ttgcttttct
     1921 tgacgttcgg ctccagcagg tacaccgtct ccccgaactt ctggtattca cgctgccgtt
     1981 cggcgacctt ctgttcgaga tacccgtcga aaccgcttga aaccactttg cgcacgtagc
     2041 gcgcatggaa ttgttgaaag agctcggggc ttcccgtcaa aaaccgggcc tccatcatgg
     2101 aggtgcgcac agtcagatcc gctaatccca aatcgataca gtcctgaatg gtgcggacgc
     2161 tgtgcccgac ctgaaatccg atatcccaga gcggatgcag cacctgcttc accagttcag
     2221 gaatgacctt ggccgcatcc tgatgaaaga ggaacatcaa atcgatatcg gagtgcggcg
     2281 ccagttcccg ccggccgtag cccccgatcg ccaccaggca gcagtgctgg aatcctgcgg
     2341 tcgtgagcgc ctcgccgccg gtcctggccg cggtccggta ccggccgatg atcaagccat
     2401 cgaccagatc cgttgtggcc gcaaccactt cgtcgccaga cgcaccggcc agtaaccgct
     2461 gctgaatcgc ctggcgctgt tcagccagca gttgagacac cggaatggca gctgcgtcct
     2521 gcaccatatg aaaccccgcg tccaacgcgt gcgacatact cagagcgcgc tttctcccgt
     2581 ttcaccggtc cggatcctga cggccgacgc gaggtcccgc acaaatattt tcccgtcgcc
     2641 gatgctgccc gtctttgcgg cgcgcgtgat ggtctccaac acccgctgga cctgaccatc
     2701 attcaccgcc acttcgatct tcaccttcgg cacgaactcg atggtgtact cctggccgcg
     2761 ataggtttcc ttgtgcccct tctgccggcc aaagcccttg acctctgtga cggtcatgcc
     2821 ctgaatcccg atctcgagca gggcatcctt cacttcatcg agcttgaacg gtttgacgat
     2881 ggcttcgatt aatttcatcc tggcctcctg agaccgccga ccgcccacag tcgatggcgt
     2941 cgtatcacga ataggcgcgt tcgttatgtt gactcaaatc gagaccggtc gcttcctctt
     3001 cgggcgagac ccgcagtccc gtcatcgcat cgaccaattt gaggatggca aaggtaccga
     3061 ccagtgagaa gaccgtcgtg accaccacga ccaggagttg gacgccgaac aacccgggat
     3121 tgccgaagaa cagtccgtcg gcgcctccgg gattgacgac tttgctggcg cagagacctg
     3181 tcgccagcac tccgatcacc cccccgactc cgtggatccc cacgacgtca agcgagtcat
     3241 catagccgaa tcgccccttc cagacaatcg ccgcgtagca ggacatcccg gcaaccaggc
     3301 cgatgaggat ggcccacagg gggctgatat atcccgctgc aggcgtgact gtagccaggc
     3361 cggccaccgc gccgctggcc aaccccagca ccgtgggttt cccgcgatgc atccattccg
     3421 cgccgcacca ggagatggct cccatacagg ccgccgcatg tgacgcaatg atggccgaca
     3481 ccgccacgcc attcgccccc agtgcgctcc ccccgttgaa cccaaaccag ccgaaccaca
     3541 gaaatccggt cccgagcagg gtcatcggca aattgtgggg agccatataa tccgtgccat
     3601 agccccgccg cttgcccagc acgatcgcac aaatcaatgc agccgcgccg gagctgatgt
     3661 ggatgaccgc accgccggca aaatccaacg cccccagttg agcgagccat ccgccgcccc
     3721 agatccaatg ggccagcggc acatacacga gcaccgacca catggcggca aagagcacaa
     3781 ccgaggtaaa ccgtttgcgt tcggcaaacg cgccggtgat cagcgccggc gcaatggcgg
     3841 caaacatcaa ttggaacagc ataaaggcct ggtgcggaat cgtcggggca tagaccgcgt
     3901 gcggctgact ccccactccg ctcaggccga tccaatccag ccccccgatg accccgcctt
     3961 tatccggtcc gaaggccagg ctatatccga agaggatcca caacaggctg accacgctca
     4021 ggatcatgat gctctgcatg atcgtcccca gcacattctt ggtgcgcacc agcccgccgt
     4081 aaaacaaggc gagccccggc atcagcatcg ccagcacgaa ggccgacgag accaaaaccc
     4141 atgccgtgtc cccgctgtcg gctttgagcg gcgcattctc cgcccacgcc tgttccgccc
     4201 ccaatccacc aatcagggtg agtgcccctg ccaggcccac gaggaacgtt ttccactgtg
     4261 ccgatgcctt cacgctgtcc tccttcggct acgttgcctg ccaagaggcc tcctccttca
     4321 ccatgctcag gaggaggccc gggcagaagc ttagaacgtc ttcgtgaact tcagcttata
     4381 aaaatcctga ttgtctgtca gatcttttcc gaccgtgaac cggaaggcca tgtttcccgg
     4441 caacttcatt tcaacgtacg ggccgatcca acgatagtaa tcctgagccg cccccggcgc
     4501 gctgctatcg cgcgtcgtca gcaaatgctc atagtgcgcg cccatcgacc acatgctgtt
     4561 cacccgcacg cccgcgctca cccagtagtg cagaaagtcc caggttcccc ggccaccgcc
     4621 ctgaatcggg cccagacagt tcgtgccccc gggattgccg cagccgatcg ctccgccgcc
     4681 gccgctgccg ccctcgctgc ggatcgcctt gtagtagccc atgtagaact cgccttcgaa
     4741 acgattgtcg atgtagttcg caatgatgtt cggcaccgcg ccttcaaagg ccgtggtgcg
     4801 ctcattgacg ctgccgccgc cgttcggaaa gaacccgcca cgggacgaca acaggctgcc
     4861 atgcacaaag ccgatcatcg gcgtgacaga caagcgtttt tccaggaacg tgaaattgag
     4921 tcccacgtcc gtttcaagcc agggcgcgtt gtcatgcacc ccgacgccgc tgatcatggt
     4981 ccaataggtg aagttaaagg cgagggcgat gttatcggtc agaccgtagg tgccgtagat
     5041 ggatggattg aatccgaaga agctgtcggc ctgcatcgcc atcgtcaccg acacggggtg
     5101 tttggtggta tccatcaagt cgtccgtcgt cgcggcctgc gcctcgacca gcgcgcctcc
     5161 cccgccgcct gccatcaatg ccaatcccaa cacccatgcc cgtgcctttc gcccaaccaa
     5221 catattcatg acgcctccaa agagagaaga agtgaaagtg gcccgctccg agaccatcgt
     5281 gcccgacaat ctggagttcc gtctctctgg cgccattgcc agtgttgctg accgacgtcg
     5341 ttgtcggtcg ggatgctgct tgtctaccga tacccgttgg tgatcggcat ccgccgatcc
     5401 ttgccgaacg ccctatgcgt aatcttgatg ccgagcggcg cttgcctgcg tttgtactcg
     5461 ctgcgatcca ccattatcat gacgcgtgcc accgtctccc gctcgaaccc catggccacg
     5521 atgtcttcga gggcccggtc ctcctcgaca taggctttca gaatggggtc caacaccgaa
     5581 tagggcggga gactgtcttc atctttttga tcggggcgca actctgcggt cggaggccgt
     5641 tccaggacac gttttggaat gaccggttcc agaccgttca gattccgcag ttgtgacagt
     5701 tcgtacacca tggtcttggg cacgtctttg atcaccgcaa atccgccggc catgtcgccg
     5761 tataacgtgg cgtagccgac gctcatttcg ctcttgtttc cggtggtcaa caccaggtgt
     5821 ccgaatttgt tggagtaggc catgagcaga ttgcctctga tcctggcctg caagttttcc
     5881 tcagttgtat cgggacggtg tccggagaat ggcttggaca gcgcacgcaa ataactcttg
     5941 aacgtcgtcg tgatcgagag agtatccacc tggatgcgca gacgttgggc gagatcggcc
     6001 acatcctctc gactggctcg cgaggtgtaa ggcgagggca tgaagacccc gaggacatta
     6061 tccgcgccga ccgcatcgac cgcgatcacg gccgtgaggg cggaatcaat acccccgctc
     6121 agcccgatga cgacccgctt gaacccgttc ttttggacat aatcccgcac gcccaggacc
     6181 agcgcgcgat aggcctcctc cagccgatcc aatggcgatt ccatggccgg cacggcgatt
     6241 gacgacgatt tcctcgccgg cacccgcacc gcaacacgat ccaccagcgc ggccactcgc
     6301 ggcggcaagg gcctggcgcg ccgttcaccc tgtcgcgcgc gccccaccgc cgccacatcg
     6361 agatccgcaa tcaaaagatc ctgctcaaag gacttacctc gcgccaccac ctcgccggtg
     6421 tgatcgacga tcacgctacg gccgtcgaag accaattcat cctgcccacc cacggtgttg
     6481 gtataggtga ccatcacgcg attctcgcgg gcacgggtag ccagcacctg ttcgcgcagt
     6541 cggctcttgc cgacatggaa cggcgaagcg ttgatgttca cgatgacctc agcccctgcc
     6601 gccgcctgcg cgcgtgtcgg accctcggga aaccagatgt cctcgcaaat gttcacgccg
     6661 atggtggtgc cgttcagcac cagcagtggc agacgcgtgc cgggccggaa ataccggctc
     6721 tcatcaaaga cgccatagtt cggcaacagc cgcttgcaat agttggcgac cagccgtcgc
     6781 tcacatagca cagctgccgc attgtagaga tcatgccggc cggccgggga aaccgcctct
     6841 gcctccgacg gtgtcacgcc ggttgcctcg cgcccgacat accccaccac caccactaat
     6901 ccgtgcgctt ccgccgccac cgcctttaac gcacgctgcg tgtcttcgat gaagcggggc
     6961 ttgaacaata aatcctccgg cgggtatccg gtgatggcca attcgggaaa cgccacaatg
     7021 tcagccttgg cccgacgcgc gtcattgatc caggtcttga tcagcgccgt gttcccgacg
     7081 atatcgccaa ccgtcggatt gatctgagcc atggccactc gcaggacgcg catcatcagc
     7141 tttcccctgc actcgcactt tgctcaaatc ggtcattcaa cgaggccgca aggagctcag
     7201 gcaccgaggc gtactgtgag ccgtacgtcg aggtggctga tcgactgaga acgaagttga
     7261 gggccgattt cagcatagtg ctcaaaaaaa aagtcctcgg acccaccgta tctcggtgga
     7321 ccagaggacg tcgttgtcct gcgccatctc tataagggat agcctcctga gactccgttg
     7381 tccctggaaa agctggcgat ggtatagcac cagccggaat cggctgtcaa ccaatccagg
     7441 cgaggtttgc ctgaaatccc cgtagcctgg agacgggtct atgttacaat cccgccccat
     7501 gcaccgcgtg aggtatcaga ggatgtcacg agcttgtgag ccgatgcgcc tgagaaaatc
     7561 ctggctgctg gttctcacct gcttgctgct ggtcgcctgc agcgccacgt ccccgctgat
     7621 tcccgtcggg gaagggccat taggaacggt ctcgcttgaa cgcctggcca gccggggcac
     7681 cacggccaga tacggcagtc cccagagcgc cttccaggcc tctcatccgg cctcggtatc
     7741 ggcatcggta atctcacgcc tgctttccgg cctctccgtt tccggcctcg agcggccggg
     7801 tgcggccctg agacaagagc ggtatccgct gtttacccag gaagaaatgg agtttttctc
     7861 gccgctcatc gtcaaggctc tgtcccaggc cggacctgac caacgggtgc ggttcaccct
     7921 tcaggacgac gggctgatca cccagggaac gctctatctg cacaagacca cccttcgggt
     7981 cagtctttct cactatcgcg cgtcgcaggg gcaaagcgac accaggccga cagcgctcac
     8041 cttgtcgttt acgccatcag aagcactcgt gcgagacgat gtgccgcaat cctggatgat
     8101 tatcgaaccg gaacaacccc gtatcgcggt gtcgctcgag gttctgaatg agctccgcgc
     8161 cgccgtttcc gctccgaccg cgaacaaacc agtcgctgta ataccagttg ctccggcccc
     8221 ggctgcatcg gaacagacca acctgcaaca ggagctgcaa gccacgaagg atgtggtcgt
     8281 caagcaggcg caggaacttc agcagctcaa gacagaactg gaatcgttgc gacgcgaact
     8341 cgccgagagg gactccacca cgccgaaagc gaaaccgaaa gcagcccccc gcaaaacggt
     8401 cccgacgccc tgagctaggt gctgacgatt gttacaagtc cgtgggctct tctcctgtca
     8461 ataatgtcga agcgcaggcc ttgccgggcg aggcggtccc gggtgaacgc catcgcgccc
     8521 ttggccagca tcaatgccat agtacgagca aaacggaagc cgcgggcatg ggatggtgac
     8581 ttcagaaatc aatcgagaac gtcacccgag caaccgagag cgtcacagag tgcagcgccc
     8641 gcttcgctga gggagcggta gacacacgtt cgacaataca tctctcccta ttgagccagc
     8701 ggaccagcca agacctcctt cgcatcatag acatcatctg cgcccgaggg cttcttaccc
     8761 ttgtacatcg tcactgtcat agacgttcgc cgcgaaagcg ccaacacgtc tgccctctgc
     8821 gcgagatgga agaagttgta tccctcgcgc aacgtcagtt ctgcgcagcg ccgccgcaaa
     8881 tacgaatcga gctgctcctg ggaggtaaag gaactgacgc gatattctac gcggtagaca
     8941 ttctccctga gctgctcgac ctcatctttg tcggctccgt tgagcggctg atactgtccg
     9001 gtggtgcaag cggctacagt gacaagacat gctatgcacc acgccttacg cattgccttc
     9061 acggttatcc tcctcaggcg ggcaaagaat gaatcacccg acaacataaa acatgctgga
     9121 ccgccggctt ccgaagccaa ctgtactgag aaaccgcacg atccttatta cgccgggatc
     9181 ggcactccgc actgacatct ccgctccacc ctctgctgat gaagaagagc tccaggctcg
     9241 tgttcgactg tgacaagctg gcaaatgccg cactgtgaac gccccatcga caccggttgc
     9301 tcacgcgccg actcctgagg tcgcactcgc ctccataccc gccaccactg cacgacgatc
     9361 tgcaacacat cacaaaaggc cagatgaaac agaaggaacg agaggtagag gagctgcgaa
     9421 aggaactgga agacatcaaa cgtcagctgg gcaacacctc gacccaaggc ggccagccac
     9481 cctcaagtag gccataacat ccgaagatag tagaactgtc cggtcatccc cggtttttat
     9541 cggcccggtc ttcgatctcg cccgccaaca aaatcgcctc ggcaatctcg cgcatggact
     9601 tgcgaagatc catgctctgt cgctgaatca acttgaacgc atcttcttcc gagagccgtt
     9661 tcgaccgcat gagatagccc ttggcccgat ccagtaattt gcgaacctgc aaggcttcct
     9721 gcatctcgaa ggacttttcc aggagcgtcg tgtgctcgat ggatatggct gcctgattgg
     9781 cgatggcctg catgagtttc acatcctcgg acgtgaaggt atggggcttg gaggtatacg
     9841 tattaatgac accgatggcc ttctcacgca ccagcatggg cacgcaaagg agcgaacaca
     9901 gcccttcttt cgcggccatg tccgggtaca tgtaggagcc ttctttggtg acatccggga
     9961 caatgatcgg tcggcgatcc tgaaccgccc gcccgctgat actttggccg atcttcacat
    10021 tgggcttgcg ccggtactgc tcgctcaaac tttgcgtggc agcaatgcgc agttcaccgg
    10081 tcggttgatc caggaggata atggaacaga ttttcgagcc catcatttgc gccgtcatcg
    10141 tcacaatcag ctgcaacacg tcttccatta aacgattcga cgagaccgtt tcggacactt
    10201 gggacaaggt atcaagttgc agcgctttgc gggtcatctg atcgtagagc cgggcattct
    10261 cgatggcacc gccgacttgc gtggcgatgg tcgacaacag cgccaactca tcagggcgat
    10321 accgccgcga ccgtttgtgc tggacgttga tgacgcccac gacctcctgc ttggtcgtaa
    10381 tgggtacgga gacaaacgcc tgataacgat cttccggcag gttatgaaaa aacttgaacc
    10441 gagaatcatc gctggcgcta ttgggaatca ccacgcgagt tctttcccgc gcgacccagc
    10501 cggtgatccc ctcccccaat ccgatcgtga tacggccaat gagcttcgga tgaggatttt
    10561 tggaggctcg aaggatcagc tcgtcccggt tatcggacaa caggtacagc agacaggcat
    10621 cggctttggt cgcttcaacc accacatcga caatatgccg aagaacggac tccagatcga
    10681 gcgtgctact gatcgattcg ctgatgcggt ggaggacatc gacttcgcgt gttttttcac
    10741 gcaacgcctg ctccaattga gggactgttc gcttcgatgc cattgcgctc ctaccgccgc
    10801 cgcttgttgt tcggaatgaa ttgccgggaa cgggtgttgt cactgctgac cgtgtcatac
    10861 caggcgcgag tctgttcctt cgctaacgga acgatgcgga ccgatccgat ccgttccggg
    10921 accacacagt agacggttcc ggcagacacc tttttgtcct gttgcatcgc atcccataac
    10981 gcgcggaacg gcaccttcgg aacgcgcacc ggtagaccgg ccgctgcaac cagggcacgc
    11041 aggcgggtca cgacatcctc atgacaatag cccaggtgcc ttgccagatc cgcttcatac
    11101 accattccga cggcgaccgc ttcgccatga atcaggccac ggtatcctcc aagagactcc
    11161 aatgcatggc caatggtatg cccgaaattc aagatacgac gccggtcggc ttcgcgctca
    11221 tcctccgaca ccacctgagc cttaatttcg caggaacgct tcacgatgtg tgcgacgggt
    11281 gcatcactca gcatcaaaat cggcgcgata tgctcttcga gatatttgaa aaacgactca
    11341 tcctcaatga ccccgtattt gatcacctct gccaacccgg cgatccattc ccgctcaggc
    11401 aacgtacgta gtgtggcggg atcaatcagg acggctcgcg gttgattaaa tgcgccgatc
    11461 agattttttc ctttgggatg atccaccccc gtttttccgc cgacgctcga atcaacctgc
    11521 gcgaccaggc tagtcgggac ctgcacaaag ggaatcccgc gctgatagat cgctgcagcg
    11581 aatcccgtga tatcgccgat gaccccaccc cccaaggcca gcagcgttga actgcgttcg
    11641 aagcgggcgt tcaccagagc atccatcacc gttccgatgg accgcagggt tttagtgcgt
    11701 tcacccggcg gcaacacgat gggaactact gtatatccgg cagccttcag cacgcgtatc
    11761 acgggcttca aataatgccc ggccagattc cgatcggtga cgacgcccac cttcccggcg
    11821 cagcggagtc gcgtcatttc cacgccgatc tccttcagca ggccacgccc gatctggatg
    11881 tcataactcc gcgcacccaa ttcaagatgg atcgtgtctc gaggcatatc aggagtggat
    11941 gttgccatga actgttatcc cgtgacttgg agagagcctc gtcgtcggcc tcgcctagcg
    12001 cgagcgcctc accacgggca ctaaggtcct tgaattaccc ggtcggcaat ggtgtggctc
    12061 agaaccggat ggtgaactgt acgattcaga gggagaagaa gcccggaaga agcgccatcg
    12121 agaacgggga ggagacacgt tccatgggat tcgcccccat tgagacagcg taccatcatc
    12181 aatgggggcg attattagcg tgtcgagcgg ggacctgtca agttgcggag cgcacgatcg
    12241 tcggagtcag gaagatcaac agttcctgct tcgagacgtt ctcggtcttg ttcttgaaca
    12301 gccagcccag gaccgggacg cgggacaggt acgggatacc cgcgacgttg ttcgattgcg
    12361 tatcgacaaa cacgccgccg atgaccatgg tttccccgtc gcgcaccagc acctgagtgg
    12421 tggcttcgcg acgatcgatg ctcggaccag cggggttgct tcgcgcgccg acggcattcc
    12481 tcgtggcccg cactttcatc agaatttgct tgccgatttc tttcggatca cgggacgtaa
    12541 tttgcggcgt cacgttcagt tccaggttgg cgtccacaaa tgtggtctga gttccttgca
    12601 aggaggtcgt ctggaacggg atcgattcac cttgcgcaat cttcgcatcc cgcttatcca
    12661 aggtcgtaat cttgggcgca gcgatgacct tcgtcaaccc gagcaactca ccggccgaca
    12721 accgcacatc caacatcgca ccatccgttt tgccgatcga gaatccggcg ccaggcacag
    12781 acggcaatcc cgggttagcc ggcaagttga tcaggaagtc cgacacctgc gcaccgaagg
    12841 ctcctgtggt gccggtcttg aaagcggagg ttccgctcga ggcgcccaac tggttgacgt
    12901 tctgaatacc ccactgcaca cccaacgacc gggtatacgt cgtgtcggct tgaacgatgc
    12961 gcgcctcgat ctgcacctgc ggcacctcga gatccacgcc gtccagcaac tgccggagga
    13021 cttccagctt ggactccgtg tcgctgatga tcaaggcatt gctcgcagcg ctgacggtca
    13081 tggtgccgcg tgggctcagg ttctgccgca aggaggtttg cacttccgtc gcgttgagat
    13141 tgcggatata gaacactctc gtgacgatgg gctcagcctt cgccttggaa tccttggcgc
    13201 gcgcctcttc gtcctgctgc ttggcaatat tctgcagagt atccacccac acgatgttgc
    13261 cttggcggat catgcccaga gcgttcatct tcagcagcat gtcgagggcc tgatcccagg
    13321 gtacattggc caacttcata gtgactttgt tcttcacacc ctcgccgacc acgatattga
    13381 agccgctgac ttcagcgatc aaacgcagca cattgctgat gtccgcctgc tggaaatcga
    13441 gagaaatccg ccgcccgaca aagcgggacg aaccgtttac cacttcgttc gtctccggct
    13501 tccggtcttc cttttgaacc gactccgccg tcaattggat gggctgcaca cggaacaacg
    13561 catggggcgt cttatgggag actaccatcg agcgcgctgc agtctgttcg gccgacggcg
    13621 aggcctcgct ctcggccagc ttcacatcat tggtgggcac agacttgggt tccagcatga
    13681 gaaccaaccg gccgtcgact gaggtgacgc tgtgctccgc cggctgggcc aggtcaagga
    13741 ccaatcgcac cttgtcagcg tggtagccaa atcgcacttt cgacaacaac gcatgaccga
    13801 cggccaactg cgtctggcgt ccctgcgatt gaatgtgcgg catatcgagc accatgcggc
    13861 gatcaccgac cattttgacc gtgtggtcga acaccccgtt accggtcagg atcagcgcca
    13921 ctcgtccgcc ttcaggcttg gcttcaacgc tcgtcagcaa tgttgcggtc ggagtggccc
    13981 cggtggagtg ctcctccttc gctgccgtga actcagcaga agtcgcctga tcagtggcct
    14041 gcgtgaatcc ggccagtccg gtcgtttccc ccggtgcggc ggcttgcacg tagcccgcaa
    14101 ggcctaacag tccggccatc acagtgacac tcagcagcgg atgtacacca acctgtgttt
    14161 gtttcattct gtgccctctt tcgggtgcag gagcttgacg tattcgcgct cctgtttatt
    14221 cccgtacacg tccgtgaacc gctcttgaac gatgatgcct cgttcggtga ttgaactgac
    14281 cacaccattg ttaggcccga ttcgtgttcc ccgacggatg ctatacccct tgccatccgg
    14341 cgtttgaacc atggccgtgt acccgtagtt gccccacagc acaccgatca gactcagttc
    14401 cgtgaggccg acacgctgca gcgggggaag actcgcatct tgctccacct gctggcccag
    14461 ctggaccatc ggcaggaagg ggtctcgacg tcccgaagga tcgtaggagg tcccggaaaa
    14521 ctccatcgac agcgaatcac ccggctgcga gaccgacgcc tcgacacgag gagccggcga
    14581 ttccattgca ggagccggct tctgcccctc cggcagcggc atgaccttca gggagtcggc
    14641 gggccgcatg gaggcgatct gccgcaagtg cggcagggat ttcgactcca ccggcatggc
    14701 agtaccgcca ataaccagca ctgcggctcc gatgctcatt ttccagcaag ttcgtgtgtt
    14761 cacggtacgt cctcttacat tggacatgcg ctgggctcca ttcctcactt cggcttcgcc
    14821 gcaggcaccg gcgcagccgg cttcttctcc tgcggagcgg cataggcgac cagatcaaag
    14881 actgtttgcg tcaccacacg gccttggtcg acccgggcag cgccgatccg gacatcctga
    14941 acggtcacga tacgggacaa cttgctgatt cgatcgaaga agatggcggc tgtatggtac
    15001 ccgccggcca cttctacgtt gatcggcatt cgaatgaaca acttcgaagg atcttcggct
    15061 tgcgtgcccg gcttccacaa cttcacatcc aggcccaacc gcagtcccag atcggacacc
    15121 tgcttcagca acatgacggc ttcttcttcc ggcgggaggc gttccttctt cgccgccaat
    15181 tcgatctcca actgcttatt ggccgcgacc agctcatcca ggtgtttgac cttgagcgtc
    15241 aggttctgga tctcggtatc caactgagcc acctgccctt gcacggcttc cagttcgacg
    15301 gtcttgggat cgacgacgta gaaataaaac ccgactaaaa tgcctgccac cagtaagcca
    15361 agcagcgcaa ccttttggcc tgtcggaatg ctgcggaggc tgtctaagct gatcgcattc
    15421 agactcatgt tagcctttca tcgacaggtc aagtcggaat tgataggtgt tcatcttatt
    15481 gtccagccca gcccggctct ccatcaattt gatggcgccg aattgatcgg tccgccggag
    15541 gttattgacg aattcaacaa cgtcatcgtt cgtcaaagcc cggccctcaa gctcaacgct
    15601 gttccctttg agattcagcc gcaccagcca gactttcagg ggattcaggc tctggctcac
    15661 atgatccagc actttgaccg ggcccgtccg gctcttctcc agctgatcga taatgcggtt
    15721 cttcgcttcg agttgctttt tcttatcttc aaagtcctgg actgccttca cctgctcttt
    15781 caactgcgcc acttgcttgt ccttgagctg cttttcgctt tgcttggcct gaatgtcttc
    15841 gtcgagcgat gaggcgtaga accaacaccc ggtcaacgtg atcagcagta ctccgacgcc
    15901 gatgagtgcc tcggcgcgaa catcccactg cggcttggct ttcctggacc gaggtccagt
    15961 tgcgagcaag ttgattctaa tcatcggtcc cccaccgtcc gcagtgcgag gccaaccccc
    16021 actgccgcaa gcgaccccat ctcggccaac tgttcaggat cgacattgca ctgtgaggtg
    16081 tcgatctcat taaagggatt cgcaatttcc acatcgacat gcatccgatc gcgaagctgc
    16141 tgagccaacc ccttcacctt cgctcccccg ccgaacaaca agacccgcgc aatttcgctc
    16201 tctgaggacg tggtcttgaa ataatcgatg gtgcgtgcaa tctccgatgc cacttcggca
    16261 ttgacgctct ccatcaccgc cgcaagtgta tgatcgtcat ctccgtcgtt tttcttgagc
    16321 tgctccgctt cctcgtacga cacgcccatt tctctctgta cggcttccga gtagcgattt
    16381 ccgcccagag ggatatcacg cgtgaagagc gacactccgc cgccgacaat gttcacattc
    16441 atgacgctgg cgccgatgtt gaccagaatg gtggtgtcct cttgagtaga gggcgaggtc
    16501 acgccataca tgttttctac ggcaaatgcg tccacatcca tcacgatcgg caccaagccg
    16561 gccgccttga ccaattccgt gagttcgttg atcttgtctt tcttcgcagc caccagcacg
    16621 atctgcattt cggtctgctc gtccgggttt tccgacggcg gcaagacgta gaaatcgaga
    16681 ttgacctcat taatatcgaa cggaatgtac tgttcagccg ccagcttcac ttgggcgtcg
    16741 agttcctcgt ctggcatggg cgggagagta atcttcttga cgatgaccgc atgaccggag
    16801 atcgagacgg ctacctgctt caatttcacg ttgtgctccg ccagcaattc cttgatggcc
    16861 gagacgaccc gcccttcgtc catcaccgtg ccgtccacaa tcacctcggg ctccagttcc
    16921 ttcacgccga acttctgcaa ggtgtagcgg ccccggtgct ccttgatctg caccagcttg
    16981 atgctgctcg atccgatgtc cagccccaaa agctgtttct ggggggaaaa catcgacaga
    17041 aaatccatgt ccgtgaggtg tttcagtgaa gccagcatgc ctttgccctc tctacgcaac
    17101 gtctttgcgc ccgccaccca tcacatgctt gatctgttcg acattttcgg ccgtatagag
    17161 acgccaattt cgccaatctc gcggcggccc ggtaatcaac ccttcgcgct cccaacgaaa
    17221 caacgtcgcg cgcgagatgt cgaacatctc gcagacctcg ttggtcttgt agagtttctt
    17281 tttttgacca tcgttcactt tcttcacgca ccgcctcaaa cgccactatt catcgcgtaa
    17341 ttcgagctca cgaaattaag tatagttgat atagtccacc tgtcaagaaa gtggcctccg
    17401 tgagggcaga caggagaaaa atggggaaaa gacgctctgg gactaggatt tctgcaggtc
    17461 gcggttggtc acggatacgt cgtaaccgag ggcggcaaat tgtgcctgga ggcgcagcgc
    17521 gatggtcacc gaccgatggc gccctccagt acacccgatg ccgatactga ggtagctccg
    17581 ttgatcccgt tcatacagtg ggatcagaaa ggcaaagagt ttttgcagat gttcgaggaa
    17641 ctggccggcg gtctcgtctc cgaatacgta ctgctgcact cggagatctt ctcccgtcag
    17701 ggctttcagc tcggggacaa agaaaggatt gcggatgaag cggacgtcaa acagcaggtc
    17761 gatatcgtag ggcacaccga atttgtagcc gaatgtgacc aatgaaatgg tcatgcgtcg
    17821 ggcagtcgtt tcctgacgaa actgcctgat cagcagatcg cgcagttcgt gcaccgtcag
    17881 cgtggaggtg tcgatcactc gatcagcatg ttttcggagt tcgctgaggc gttcgcgttc
    17941 gaaccgcacc ccttccacaa caggcatatg cggcaacagc ggatgcgggc ggcgactttc
    18001 tgagaaccgc cggaccagca cttcttcgcg ggcttccaga aacactaact gcagggcgtg
    18061 tccctgcgac ttcaattcgg cgagtacttt tgccaggtct ccgaaaaata cccgttcgcg
    18121 aatatcgatc cccagggcca cattcttaat ctcgccgccc tgctggtggc acaattcgac
    18181 gaatgtcgga aggagggccg gaggaagatt gtcgacacaa aaatagcctg catcctcaaa
    18241 ggctttcagc gcgtgactct ttccggaccc ggaaagaccg ctgatgacaa ccagattaag
    18301 cgcggccatg tgcgacgcga gcacggtcgc tcgcaggatc aatcagggac agtcttccgt
    18361 ttggcagccg ttggagcact tgaatagacc cggaaagcgc gttcacaaac atcaaaagcg
    18421 gcagcttctc cccattgagc gtctcgaccg cttcctcgat cgtcagggct tcgagcctgg
    18481 gacggaccac ttccatgccg tcatcttttg cgcgcggggt cttgcgagcg acggcacgta
    18541 cgcgcggctg atcgccgaat ttgtgattga ccttgcgttc cttcaacttg cgtagctgcg
    18601 cgccgagttt atccacgact tcatcaatcg acgcgtacat ttcttcggtc gtggttttgg
    18661 cttgcagccg gcgtccctgc acgacgccca cgacctccgc cacatgatga aacttttcca
    18721 cactcaacaa aatttggagc gtgcccagct tcaacccgta gcggtcgagc cgctccatgc
    18781 gtaactcaat atactctcgc aacgccgggg tcaccgccac atgccgtccc gtgatcatca
    18841 aacgcatgcc atcctcgttt ctcgggcctt gcacgcaagg ctgcgttcaa gcccgttgcg
    18901 acgattgttg taccgccata gagccatctc catggtgcca gacttcgcgc acctcaaaaa
    18961 aacttccgcc gttgcgtggc agagggaatg ttatcctctg cgcgatattt ggctacggtc
    19021 cggcgggcga tcaatacttg ttgggtccgt aatcgggcgg caatttcttc atctttgagc
    19081 ggctttctcg catcttcagc cgcaaccatt tgccggatca tttcccgcac ggtgagtgag
    19141 gacagcatat ccgtcggttg atcggcgcgt tgcaatccag cattgaagaa aaatttcagc
    19201 tccagcatcc cctgcggaca atacatatac ttgttggccg tcacccgact gatggtggac
    19261 tcatgcatgc cgatatcttc agcgacctgt ttgagaacca atggcttcag gtgctgaatc
    19321 ccatgttcga aaaacccttc ctgaaacttc acgatgctgg agacaacttt cacgatcgtc
    19381 ttattgcgct gctcgatgct ccggatcacc cactgcgcgg cgcggagctt gtcgtccaga
    19441 tacgctttgg tttccgccga gccggactgg cctgaggaca tcaattgctt atagtacggg
    19501 ctgatccgca tgcgcggcag gccatcatca ttcagcaaga cctcccactc cccttcgttc
    19561 ttgacgacga agacgtcggg cacaattgcg taattctggg tgttggagaa gggacgccct
    19621 ggcttcggct ccaagccttc gatgatgcga gtcgcctcga atacatcgtc catggaaatg
    19681 ttcaaggcct tggcaatacg gttatattgc ttcttttcga gatccttcag atgatgcagg
    19741 acgatggctt caagcaccga gcccttcagc accccaggcc gagaccccag agagcccagt
    19801 tggctccgcc ctaaaaactt gagttgaagc agcaggcact cggacaagtc tcttgccgcc
    19861 acgccgttgg gatcgaaccc ttgcacatct ttcagcacgg attcggcttc cgctacggaa
    19921 tattcggatc ctgccaccag ttcgtccagc gtcatccgga gatagccgtc atcgtccaaa
    19981 ttgccgatga tgaggcggcc gatggccttt tcacgatcgg ataagccgga caacgacagc
    20041 tgccagacca ggtggtcttc gagcgacgtc gacttggcca ccgtctgctc ataggaggga
    20101 aactcttcct tggatgagga gctgtattcc gtttcgccac ggcgcatgtc ggtatcgaaa
    20161 tagtcttccc aggtagaggc ggaaaactct tcggcatttt ctccgctctc tgccggcttg
    20221 tcatcgcctt ccccgcgcgt ctcagcggcc acagtcgtcg ccgtatccgg ttgttcgcgc
    20281 tcagtggctg cagtttcctc gctctcctcc gtctccgcca ccagttcgtc cagcaagggg
    20341 ttttccatga ggtgctgctg cagactttgt tggagctcca agcgggacaa ttgcagcagc
    20401 ttgatcgcct gctgcaattg cggcgtcata atcagtttct gactaagccg aagatccagt
    20461 cgcaacttca tcgccccact ccctgcctgc tacaggcgaa atccttcgcc caaatacacc
    20521 gcccgagcca tttcactttt ctcgatcacg ccaggaggac cggcttcgag aatcgtgcct
    20581 tcattgatga tataggctcg gtccgtaatc gagagggttt ccctcacatt gtgatcagtg
    20641 atcaataccc cgatatgccg ttgcttcaat cgaatgatga tttgctgaat atccgcgacc
    20701 gcaatcggat cgattccggc aaagggttcg tccaacagca tgaagagcgg actcgttgcc
    20761 agcgcgcgcg taatctccaa tcgccggcgt tcccctccag ataaggcgta ggccttactt
    20821 tttcgaatat gcaccagatc gagctctttc agcaacgttt ccacccgctc catccgttca
    20881 cttctcgaat agcctagcat ctcgagaatc gcaaggatat tgtgttccac cgacagccgc
    20941 cgaaagacgg acgattcttg aggcaagtaa ccaattcctc gccgggcccg cttatacata
    21001 ggcaaatcgg taatgtcgtt gccactcaac gcaatctgtc cctcatccgg ctgacacagt
    21061 cccaccatca tatcgaagat ggtggtcttc ccggctccgt tcggccccaa cagtccgacc
    21121 acttcaccgg cctgcacgtc gagggagacg cccttgacca ccttgcgccc gcggaagctc
    21181 ttcaccaacc cgctggctgc caagcgatcc gctttcgccg ataacgctgc cacgccttct
    21241 tgcggcgtct ggctggtgat tggcttggtg tcaatcaccg cttgccaccg ccttcacctt
    21301 cgataacgac ctgggagtcg ccctccacca cacttcgatc ttcgtccaga aacataatga
    21361 tgcgctttcc ggacacacgc gttcccttct gccaggccac aggttcgccc gtgagcacga
    21421 tttttttctg ctcctcataa tacacggcct tctggcacgt ggcttggccg tcttctttct
    21481 taatgttcac acgaccggtc gcctcgacca tgcgaatact gcgttccgat acggcaggcg
    21541 ctgcatctcg ctccttcgat tcggccgtcg tcgggttcgt gagattcttg gattttgtcg
    21601 ggcctccgga ttctttacca tcggcgccat tgcggctcgg gtggaaagag accaccatgt
    21661 gatctgaatg cacaaccaac ggaccacgcg tcaagacaac ggctccatca aaaatcgccg
    21721 tgttttcttg attattgacg gtcatcgtcc gggacgtaat cgtagtaggg gcagaactgg
    21781 ctggaggctc tttggtcccg cgcgtttcta tcgcgtacgc gttgtgcgtg cttagcaccg
    21841 cctcgccgct aagaagcagg cacgacatcc acatgcacgt cgtcaaggat cttgaattcc
    21901 tccgtatcca tcttgcccaa caaccctctt cccgtgactt gcaatccatg ccccagaatc
    21961 gtgacatggt ctggagtttg aatttcatgc cgtgcgtcag tccatacaag gtgatttgtc
    22021 tgaatggtat agccactttg tgtctcaact acaatcggcg tggatctgtt cgacaactga
    22081 aagttcttcg tttgtgtatc cagcgtcccc tcgtccccgg atagggagag ttcctttccc
    22141 tgcgcaccgt acatggtaat ctgaacattg ctgaggatag cgcggctctc tttttcgtag
    22201 aggcgcgctt gctcggcttg cactttccac tgaacgagat cgcctttggt ctgggtaaag
    22261 gtgaagtctt gaatatgcgc atcggcagat tcggcctcga ccggcgcgac cgatcgcgac
    22321 gaagagctgg gattggagcg tgtaatgagc aaatacccaa ggaatgccgc aagaactacg
    22381 ctgagagcta agagacctcg ccgaacccaa cgttcccaca tggaaaaaag cccctatttt
    22441 aaagagcttc ccagatcaga gtctggtggc atgatagtag cattccccag aagccaagta
    22501 aacaaaaggg acggcggatg gcctgagaaa atggtgtgag ttgcaagaga atcgaggcag
    22561 ggaggaaccg aaggccacga cgacagtgac gtcatcgtgg ccttcttctc gttagctttc
    22621 tgcaggcgct gaacttttct cagtcgactc tttcttctcc gccactgacg tgtcagcggc
    22681 aggcgctgcc ttaggctttt ccggtcgtgt aactaactct attgcgacca tctcagccgc
    22741 atctccgatc cgacggcgag tgcggatgat acgcgtatag cccccaggac ggttttggaa
    22801 ccgtgacgca acgtcgctga ataacttcga cactacggcc ttgctccgca agaagctcaa
    22861 tgcgcgacga cgggcaggca gggtgccttc tttgccaagg gagatcattc gatcagtgaa
    22921 accacgaatt tccttcgcct tcgcttccgt cgtttcgata cgctcctgct ccagcaatga
    22981 agtcacgaga cttctgaaca gagcccatcg gtgtttggtt tgacgtccga gctgtcgacc
    23041 cttctttttg tggcgcacgg tagtcctgtt cctttcttac tctgaacgca cgcccgcgtc
    23101 gcctgacggc aaggcgtcga ctttcattcc aaggctcagt cccatttcgg tcaggatttc
    23161 cttgatttcg ttgagcgact tcttcccgaa attcttcgtc ttcaacattt ctgcttcggt
    23221 cttttggacc agatcggcaa tggtcttgat attggcgttc ttgaggcaat ttgccgcgcg
    23281 aacggacaat tccaattcat tgacgcttcg gtacagattc ttattcactt catcggacaa
    23341 atcttcgcta ccagcggatg gcttggcgtc tgaacgttct tcaggattga tgaagatatc
    23401 gagatgttcc cgaagaatcc cagccgcgtt ggacaatgca tcccgcggag aaatcgtgcc
    23461 gtccgtccaa atttcaagcg ttaatttgtc atagtccgtc attcgaccga cgcgagcatt
    23521 ttcgacgtgg aaatttaccc gtttgatcgg agagaaaatg gagtcgatgg caatcacacc
    23581 gatcggcagg ccttcttcct tattgcgctc ggctggaaca aacccgcgac catgcttgat
    23641 ggtcatttcc atatcaagcg cagcatcctt gtccagcgtc gcgatgtgca ggtctggcgt
    23701 gagaatcgtc acgtcaccat catgcgtaat atcggaacct ttcgcttctc ccggtccctt
    23761 cttcttgaga cggatggtct tcggcttgtc gccctgaagc gccaagcgga gactctttac
    23821 attcaaaata atcgaggtga cgtcttccgt cacaccagga atcgtggaaa actcatgtaa
    23881 cacaccttcg atcttgacgg tggtcaccgc agcccctgtc aaggaggaca gcaagacacg
    23941 gcgcagggag tttcctaccg tggtgccgaa tcctcgctca aatgcctcgg tcgtaaatct
    24001 tccgaatgtc ggggaaagag tgtccttgtc gacttccacc cgcatgggga tctgaaagtc
    24061 tttcatcgct ttaatcatga ctcccccttc attaactcgt gtgtgcccat atatcgttca
    24121 accatgatga ggtccaatca gggaatcccc aaccatgtcg gtttagcgcg aatacagttc
    24181 gacgaccatc tgctcattta caggcaacac aatatgttcc ttggtcggca aggatcgaat
    24241 cgtccccttg taggcggccc tatccaactc gagccattca ggaatgccac ggccgtccac
    24301 cgccgcaagt gcaccctgaa tcggaatcaa ttcgcgactc ttttgccgga cctcgatgga
    24361 atcaccagct ttgacaagag caccgggcgc cttcactttt cggccattga tcatcaagtg
    24421 accatgattg accaactgcc tggcctcttt tcgtgaggcg ccgaagccga gccgatacac
    24481 cacattgtct aagcgacatt ccaggaggcg cagcaaggta tcgcccgtta cgccggcttg
    24541 acgttccgct cgctcgaaaa tgccgcggaa ttgacattcc tggagaccgt aaatcctctt
    24601 cagtttctgc ttttcacgca actgtaagct gtagtccgac gtccgttgac gggcctgacc
    24661 gtgctgtcca ggaggataac tccggcgctc gatcgcgcac ttctcggtca tgcaacgaga
    24721 ccccttcaaa aagagcttct cgccctctct ccggcacaag cggcagacag gtccactata
    24781 ttttgccacg ctactacccc tcctctacct caacaactta agtacaaccg acttagatat
    24841 ttcgttactg cgaagatgcc cggatctctc ctacacccgc cgacgtttcg gcggccggca
    24901 tccgttgtga ggaatcggcg tcacgtcgcg gatcaaattg atacgcaatc cggcactttg
    24961 caatgagcga atggcggact cgcgtccagc acccggccca ttgacataga catctacctg
    25021 gcgcatgccg ttttccatgg cttttctggc tgcagcttca cccgctcgtt gcgcggcgaa
    25081 tggagtactc ttgcgtgacc ccttaaaccc ctgattgcct gaactggccc acaccacggt
    25141 gttgccgctc atatccgtaa tggtcacgat cgtattatta aacgaggcct gaacgtgagc
    25201 cactccgctc tgaacaatct tccgttcctt cttcttgcct ttcttcacac tcatagaatc
    25261 tccctcagcg catggcgcct gatcggtcta atctcttatg ctctggaacc agcgggcttc
    25321 tgtggtttgc tgccgacgcc cgagcgtctt cctttacggg tgcgcgcatt tgtcttggtc
    25381 cgctgtccgc gaacaggcaa ccctttgcga tgccgaagcc cacgaaatgt tccggtatcc
    25441 accaaacgct tgatattcat cgacacttct tttcgcaagt caccttccac gcggtaatcc
    25501 cgttcgatca cctcgcgaat cttgacgatc ttgtcttcgc tgacatcttt cacgcggatg
    25561 gccccatcaa ccccagcctt tttaagaatc gcctgggccg caacgcgacc gattccaaac
    25621 acataggtca gaccaatttc gattcgtttg tcttttggca aatcaacgcc agcaatacgt
    25681 gccataatta ccccctagtt ccttttcttg ctcgcctgat gagctggctc agccacgttc
    25741 agagattcgc cctgccgttg ttgtgcagac gactccttcc agactccgcg catgccgtgc
    25801 caaggcaacc caccgccgct catccctgcc gttgtttatg acgaggattg gcgcataaga
    25861 cgcgaacgac cccacgccgg cgaaccacct tacattttgc acaaatcggc ttaactgacg
    25921 acttgacctt catagcaatt ccatttctcc gctacttgaa acgataagta atccgtcccc
    25981 tcgtcaaatc atagggtgac aattgaatgg tcaccttgtc gccaggaagg atccgaatga
    26041 aatgcatccg catttttccg gaaatatgag ccaaaatccg gtgcccgttt tccaactcta
    26101 cgcgaaacat cgcattcggg agagtctcag ccaccgtgcc ggtcacttct atgacatctt
    26161 cttttggcac gtattggtac gccttcccgt cttagtgtga caattgtgaa agaatcttgg
    26221 ccggtccact tggttgaatc gcgatggtgt gctcaaaatg agcagaccag cggccatctt
    26281 gagtgaccgc cgtccaacga tcttctaaaa tgcgaacggc gctgcctccc atattgacca
    26341 tgggttcgat ggccaatacc ataccgactt ggagccgggg accttgccca ggtttgccat
    26401 aatttggcac ttgcggctcc tcgtgaagct gccttcctat accatgaccg acaaattccg
    26461 tcacaacggc aaaaccggcc tgctcgacat gggtctgtat agcatgagac acatctgaaa
    26521 ggcgattccc gacgactgct ttcgcaattc cctggtacat cgcttcttcg gtcacctgta
    26581 tcagacgtaa cgcctcctca cttgccgatc caaccggcac ggtaaccgcg gagtctccat
    26641 agaagccgga aacgatggcg cccaagtcaa gcccaataat gtcgccttcc ttgagtttgc
    26701 gtttcgatgg aatcccgtga acgacctgtt cgttaatcga tgcgcagagc gttttgggat
    26761 aattccggta tcctttgaag gctgggatgg cgccacgacc acggatggcc tcttcagcga
    26821 tccgatccaa gtcctcggtc gtaatgccag gttcgacttt ccccttcaac agcgcgagga
    26881 cttctgccac cactcgggaa gcctgcgcca ttaatgtcac ctcatccggc gttttgaaga
    26941 cgatcattga gcgccgagcc cgagcagcaa cgcggaaagc ctcgtgtaga cagcggccat
    27001 ttcgccagag ccatccagat cgctcaggag gttctttgct tggtaatacg caatcagcgg
    27061 ggcggtttgc tcgtcataca ccttcaatcg agcctcaatc gtttcaggct tatcatcact
    27121 tcgctggatc aacgacgctc cgcaccgatc gcactggccc tcgattttcg gtggagcaaa
    27181 ggcgatgtga aacacgcttt gacatttagg gcagctccgt cttccactga gacgtgtgac
    27241 cacatcatgc cgggaaaccc ggaagttgat aacccgatcg agcttcagat tccggccggt
    27301 caagagagcc tgtaattctt cagcctgcgg aaccgttcgt ggaaaaccgt ccagcacgaa
    27361 gcccttctga cacgaaggcg cagccaacgt ctctcgtacc atcccgatga ctacgctatc
    27421 cggaactaac tttccggcat ccatgctctt cttggcttca ataccgagtg ccgtttgatt
    27481 tcgaacggct tcccgcagca gatcaccggt agagatcttc ggccacccaa attgagcggt
    27541 aacccgatct gcctgagtgc ctttgccgac gccaggagcg ccgagaaaaa cgagtcgcat
    27601 gaggtggtcc taggacgttc tgcctcgaag ttttcctttt tgaaggaatc catcgtaatt
    27661 gcggtttagg agatgtgact caatctgctg cgcagtatct aagccaactc cgataacgat
    27721 caacagcgac gtaccgccga aatagaacgg catattcagc ttatagataa gaaattccgg
    27781 aatcacgcac acgatcgcca gatagatggc cccggcaaac gtgatcttcg tgagaacgga
    27841 ataaatatag tctgaggttc gctgaccggg acgaataccg ggaacaaatc cgccatattt
    27901 cttgaggttg tcggccatat ccaccggatt catgaccact gccgtataga agaaacaaaa
    27961 gaatacgatc aggccgacgt acatgagggt gtaaaggagt gatcccggcg cgagttgtga
    28021 cccgatagcc ttaatccacg gggtttcaaa aaatccggca atcgtcgcag gaaaggcaat
    28081 gatggacgag gcaaaaatcg ggggaatgac tcccgcagtg ttgatcttca acggaatatg
    28141 ggtgctttgg cccccgtaga cccttcttcc aatgacacgc tttgcatact gcacagggac
    28201 ttttcgtctc ccgctctcaa gaaagacgat tgctgcgacc acaccaaaca tgacgaccgc
    28261 caagacgatc aggagcggga agcttaattg accgacctta tagagatcaa atgtttgagc
    28321 cacggctgcg ggaagtcgtg ccacaatccc tgcgaaaata atcaaggaaa taccgttgcc
    28381 aatgccgcgt tcggtgatct gctcgccgag ccacatgagg aagccggtgc ccgcacagag
    28441 ggtaatcacc gtcatgaagc ggaatcccca tccgggactc aggacgaacg caccctggtt
    28501 catctgttca agaccaacgg caatcccgaa cccttggatt aacgcaataa caatggttcc
    28561 gaaccgggta tattggatga tcttttttcg accgcgttcc ccttccttcg ccagcttcga
    28621 aagatgcggg ataacgacag tgagtaactg aagaataatc gacgcgctga tgtagggcat
    28681 gatgcccaac gcgaaaatcg tcaggcgtga aagagatccg ccggagaaaa tatccaagaa
    28741 tcccagaagc gcaccacctt gcttctgcag aaattcggat aaggcttcac cgttgatacc
    28801 tggcgtgggg atgtgggcac cgacgcgata gacgatcagc atgcccagcg tgaacaatac
    28861 gcgggtccgc agctcaggta tcttgaagat gttttggaaa ctggtcagca gacgctcaaa
    28921 cacagggaat gacctcggcc ctccccccgg ctgcctgaat ctttgcctcc gctgacttgc
    28981 tgaacttgtg agcctggacc acgagaggtt ttgtcaactc tccctgggcg aggatcttaa
    29041 tcagctctcc tttgcgtcga acaaggcctt cattcatcaa gagttggggc gtaatggctt
    29101 ctgtcgtttc cagaccagcc aggcttttta aattaatgat cgtatattca gttcgaaatt
    29161 gattcgtaaa gccgtacttt ggaacgcggc gaatcaatgg catctggccg ccctcaaaac
    29221 ctgggcgctt tccgcctccg gaacgagcct tcagaccctt atgacctttg gtcgccgtct
    29281 taccatggcc tgaaccaggg ccacggccga ttcgctttgg tttgtgcttc gctcctcgag
    29341 aaggagccag atcatgcaac ttcattgggg actcacttcc agtaaatagc ctaccttggc
    29401 aatcatgccc ttcacttgat cggtggcagg acgcagcaca gtggcattaa gtttgcgcag
    29461 tcccaagccc ctcagtacca atcgatgctt atagggcgtt ccaatagggc tacgcttcag
    29521 ggtaattcgc agactagcct gcgcagtcgt agttttcttt tcagtcgcca tgatgtcctt
    29581 acgcttcact accaacagcc cgccgtagtc gcatgatttc ctgcggatcg cagagctgtt
    29641 gcagtccatt aagagtggcc ctgacggcat taaacggatt accgcgaccg agggttttgg
    29701 cgataatgtt gtgcgcaccg gccaactcga caaccgctcg aacggctccg cctgcaatga
    29761 ttccggtacc gtcggcggct ggctttagaa gcacgtgctc ggcaccaaac agtccgtgga
    29821 cttcgtgtgg aatggttccc cctttgatgg gaacgcgaac caggtgcttc ttggcctgct
    29881 caacagcctt ggaaatagct accgggactt cggcagcttt tcctttgccg acacccacat
    29941 acccttgccc atcaccgacg accaccaaag cgcaaaagtt gaatcgcttt ccgcctttga
    30001 ccactttggc aacgcggttg ataaacacta ccttgtcttt taggctcaat tcttcgggat
    30061 tgactcgcac aacgtcattc tcctttaggt cgtccgattt ttctatcggg aagcggaggc
    30121 gttccgccta acgcacttct aaaactgtaa tccgccttcg cgggatgcat cggccaaggc
    30181 tttcacgcgt ccatgatact gccgtccacc acggtcaaac acaaccattg agacgttggc
    30241 ggccttcgct cgttcagcaa tcagttttcc aacggctttg gcgccttcaa tgctgcctgt
    30301 cgatttcacg gccttccgca aggactcatc caaggtagaa gcagcggcca ccgtatgccc
    30361 ccgaagatca tcgatgatct gggcataaat gtgagagcgg cttcggaaga cgtttaaccg
    30421 cgggcgatca ctcgtcccga ctacagattt tcttacgcgc tgtttacgcc gtgctaattt
    30481 tcgatttttt tcttgggtat tcattaaatg cctctacttg ccggttttac ccgccttctt
    30541 cctcagcact tcgccggcgt atcgaattcc tttttgctta tagacatccg ggggtttaat
    30601 ggaacgaatg ttggctgcta cttgaccaac caaccgcttg tcgatccctt ttatcgaaat
    30661 gagtgtttgc ttgtcgacct tcacatcaat gccctgaggc accgtgtagg taaccggatt
    30721 gatgtagccg acattgaaac tcatttcacg gccctgaagt tgcgctttgt agcccacgcc
    30781 cgttatctct aacgacttct catagccttt ggtgacgcct tggataatat tgctcaactc
    30841 ggcgcgaacc aagccgtgca tggcacgaat ctctcgcgca tcaccagacc gattgacaac
    30901 aagctgccca tcagcaaccg cgacgctcaa tccatcggtc aacttccaat caagcttgcc
    30961 cattggcccc ttgactgata ccaaacgacc agcgaccttc acatcgacgc cgcttggaac
    31021 tgcaattggt ttccgcccaa tcctcgacat acgaaccccg ttacgttaca gcgatctcgg
    31081 ttatactgcg tcctagacga ctcctcatta ccagacagcg caaagcactt caccgcctaa
    31141 tcccgcgcgc ctggagtcac tgtcggtcat aagacctttc gaggtggaaa tgacagccac
    31201 gccgatgccg tttctcacct ttggcacatc atctctcccg acatacacac gacgcccggg
    31261 cttgctgatt cgacgcatcc ccgtgatcat tgggcgcgct tcctcgacat agcggagctg
    31321 gacagagaag atgggatgcc catcttcctg cgtctccccg taaccgagga taaatccctc
    31381 tttgccaagg atgttcagta tctgtcgttt tactttcgac acgggaactt tcacgacatc
    31441 ctggcgacgg cgagccgcgt tccccagtcg aaccaacaag tcagcaatcg gatcagtaat
    31501 catgcattcc tcttctatgc ctgcaactgc aagctttcac ctgggcgact accagcttga
    31561 cttacgcact ccaggaatct ctcccttgag gctcaaagat ctaaaacaga tacggcacat
    31621 acgaaatcgg cgcaaaaatc ctcgcacgcg accgcataag ccgcagcggt gatagtcacg
    31681 gcacgagaac ttggatttca ctgccgcctt attcttgagc gctaatcttg acacgagaat
    31741 ccccctttac tccgcgtggc ccacaaggcc gagccaacct ctctgatagc tgtttttagg
    31801 cccgaaatgg catgccgaga tgtttgagca gggccttgcc ttcatcattc gtacgcgcag
    31861 tggtcacaat ggtaatatcc atgccatgaa tcgatgcgac actatcgtat tcaatctctg
    31921 gaaaaatcaa ttgttccttt aggcccagcg tataattgcc tcgaccatca aacgccttgg
    31981 gggagatacc acgaaaatct ctgatccgag ggagcgctaa ggaaatcaag cgatccaaaa
    32041 actcccacat cctacgacta cgcaaggtca ccttggcgcc aatcggcatc ccctgtctta
    32101 atttaaaacc ggcgatagcc tttttggctc tggtcgtgac tggcttctgc ccggtaataa
    32161 tgcccaattc gctagccgcg ctctccagca acttcacatt ttgaattgcc tcgcccatgc
    32221 cgacattcag gacaattctc tcaagacgtg gcacttgcat caaattgccg tagccgaatt
    32281 ctttcattaa cgcggggatg acctgatcac gataggtttc ccgcagtctc ggtgcaaatt
    32341 gatgttcact accagcctcc tgtgaaacct caggcgctgc cgtttccttc ttcgtggagg
    32401 ctcgaggggt tgccccctta ccgcccttac ccttctctac ttttgccatg aacgtctttc
    32461 ctgttccgac tattcaacgg tttcttttga ttttttactc agtctggttc gtcgcccatc
    32521 ttcctggcgc ttgatcccta accgagtagg cttcttcgtg actgggcaca agaacatgac
    32581 attggaaatg gcaagaggag cctcacgttc aagaatgcca ccctgccgga gtttttgatt
    32641 cggcttggta tggcgcttga tcatattgag tttctctacc aaaaccttcc ccgttacggt
    32701 atcgacagac aataccttgc ctgacttacc acgctcacgc ccagtcatca ccacaacggt
    32761 gtcgcccttg cgaattttcg ttttgattcg tgccatccct accagaacct ttcttccttc
    32821 gactacaaga cttccggcgc aagcgaaata atcttcatga actttttcca gcgaagttca
    32881 cgagcgactg ggccgaaaat tcgagtccca acgggctccc cttgagcgtt gatcaggacg
    32941 caggcattac gatcaaattt gatataggaa ccatcgtcac gccgaacttc cttggtcgta
    33001 cgcacgatga ctgctcgact cacatcaccc tttttgacgc cggcctgagg aattgcctcc
    33061 ttgacggcga ccaccacgat gtccccaagc gatccgtacc gacgccgagt gccaccgagc
    33121 acatgaaagc acatgacctg cttcgcgccg gaattatcgg ccacatccat gtatgtataa
    33181 ttctgaatca taccccgccc tactcaccgc caaaaggatc aggcccttca gctcttcagg
    33241 tgtgttccgt agttactttt caggttgtcc cttgaccatg acgcgaacga cgcgccaatg
    33301 cttgtcctta ctgatgggac gtgtctcact cagctgaacg cgatcgccaa ccttacacac
    33361 atttccttcg tcgtgggcct tgagcttggt gacccggcga agaaccttct tgtaaattgg
    33421 gtggatgacc gatcgttcaa ccgccacgac aaccgtttta ttcatcttgt tgctgacgac
    33481 gttgccgtac cactcacgtc gatgttgttg gccttccttc atacgcccct tctctcttac
    33541 tttccgaccg actggccggc ctgagtctgc agcaattcca attgacgcct gaccgttttc
    33601 aggcgggcaa tgtcgcgctt cgtgcttcta acctgcattg ggttttcgag gcgaccaatg
    33661 ccgagttgga atcggaaatt aaagagttcc tggcgcaatt gtttttcctt tgccgccaac
    33721 tcttctagcg agagcccgct gagatccttc acatccatta catcaccact caacactcgc
    33781 tacaggttac tgaaactcgc cgcgcaccac gaacttcgtg gcaattggca acttatagga
    33841 agcaagcttc aatgcctgct tggcgacgtc gggagccact ccacccatct catacatgat
    33901 ccgtccaggc ttcaccacgg ctacccaata ctcgggattg cccttccctt tacccatgcg
    33961 ggtttcagcg ggcttcttcg taatgggctt gtccgggaaa attctagtcc atacctggcc
    34021 gccacgtttc acaaaacggg taatagcaat acgggccgcc tcgatttgtc ggctggtaat
    34081 ccagccaggc tcaagggctt ttaagccgaa ctctccgagg gtaatggctc cgccacgata
    34141 ggccttcccc cgcatccggc ccttctgcat ctttctgaac ttaactttct ttggcgctaa
    34201 cacagaccca ccttttcctt atcgaagttc ttagccaagt cgtccgagcg tagaatcagg
    34261 ctttaactga agcgctggca acaactcacc cttatagatc caagtcttca ccccgatctg
    34321 gcccatcgtc gtatgagctt ccgcaaaccc ataatcaacc tcggcgcgca aagtatgtag
    34381 aggaacacga ccctcgcgat accattccgt tcgggcaatt tccgctccgc ccaaacgtcc
    34441 cgccaccatg atcttgattc cctgcgcacc aagccgaagc gccgactgca cgctacgctt
    34501 catcgcccgt cggaacgcga cacgcttctc caactgagtc gcgacattct cgctcaccaa
    34561 ttgggcgtcc aactcgggct ttttaatttc tttaacggta atgtaggcct gaccggaata
    34621 ttccttctcg agggcagcct tcaacttatc aacttcagcg ccctttcggc cgatgatgat
    34681 gccagggcgg gcggtgtgaa tgatcacgcg ggtctgatcc ccagatcgtt caatttccac
    34741 cttggccact ccggcgtgat acagcttggc tttcaccatc tttcgaatct tgatgtcttg
    34801 gtgaagcagt cgcgcatagt ctttatcggc ataccagcgc gagctccagg tgtagttgta
    34861 gccgatgcga tagccaattg gatgtgtctt ctgacccatg aagaataacc ctcagtctaa
    34921 tggtaaaagc gttagctgct gtgggcggcg ttcggagcag ctactgcgat cgtaatatgg
    34981 ctagtccgct tctgaatgga gttggctcgc cccatcgatc gtgccctaaa acgcttataa
    35041 ataggcccgc agttcaccac ggcctgcgac acccacatct cgtcactgtc gcccaattcc
    35101 ttctgctcgg cgttggccac tgcagatcga agaagcttct caatgactcg ggcggcgtgc
    35161 tttggagtat gccgcaacat ggctaaagcc atgggcacct gctggccgcg aatcatatcg
    35221 ataaccactc tcgccttcct aggcgtcact ctcacgaaac gtaaatttgc ttttgcctct
    35281 gccatagctg accccacccc accatgccga ctcatcagtg aaccgacaat tacttaagcg
    35341 ccactgcctt ttcggtcttt gcttgtccgt gccctttgaa aaagcgcgtt ggagcaaatt
    35401 ctcccagctt atggccgacc atattttcag tcacaaacac gggaatgaac ttcttcccgt
    35461 tatgaacagc gaacgtgtgt ccgatcatgt caggaatgac cgttgatcgg cgcgaccagg
    35521 tcttgattaa cttgcggtcc ttcgtctgat tcatctgttc aactttcttg atcagatggt
    35581 catcgacaaa tgggcctttc gtaattgaac gaggcattat ccgctcctac tttttcctac
    35641 gcgcgatgat aaacttatcc gtcgacttat tcttccgggt cttatagccc tttgccggag
    35701 taccccatgg ggacactgga tgtgggttac cttgacctga ttttccctca ccgcctccat
    35761 gcgggtgatc aacaggattc atcaccacac cgcgaacatg gggacgcttc cccttccatc
    35821 gcgtacgccc cgccttcccg acaacgacgt tttcatgatc cacgttcccg acctgaccga
    35881 ccgtggccat gcaagtggag agcactttgc gcatctctcc agacttcaga cgaatctgaa
    35941 catacgcccc atcccgaccc atcacctggg cggagccgcc ggcgctgcgg atcaattgac
    36001 cacctttacc aggcttcagc tcgatgttgt gaatggtggt acccagaggc atattgacga
    36061 gcgggagagc attccccggc cgcacttctg cgccttcccc tgactgcacc atatcaccca
    36121 ctgacagacc cacaggagcc aagatatacc gtttctcacc atcaagataa tgcagcaatg
    36181 caattcttga agagcgattt gggtcgtatt caatggcggc gacctttgcg ggaacaccag
    36241 ccttgtcacg ccgaaaatcg atctggcgat agaggcgctt gtgccctccc ccacggaacc
    36301 gaatcgtcaa acgcccgtca ttattccgac caccagtccg aagatgaaac cccgttaaag
    36361 acttttccgg cttcttcttc gtcagtttct cgccctggat ggctgtcatt cctcgacgcc
    36421 caggggttgt tggcttatag acttttaatg ccataactgg atctcactct atcgagagac
    36481 tcgcgcttag acggtttcgt acagctcgag cttctcgccc tctttcaacg tgacaaatgc
    36541 cttcttccaa tcagatcgtt ttccgacaaa ccgtcctaag cgcttaatct tgccgcgaat
    36601 gttgacaaca ttcacacgcg agaccttaac ctttaagagt gattcaacgg cttgcttaat
    36661 ctgaatttta ttggcgtccg gatgaacaag aaagcccact gtgttgcttt gctcacgcaa
    36721 ggccgtaatt ttctcggtca gcaatggctg aatcaatacc tgatgaagat cgcctttcat
    36781 gaccacacct ctttcactcg ctccaactca ccctgcggaa tgacgaggga gtggcaacgc
    36841 aacacgtcat agacgttcag ttcttcaggt cgtagcacgg tcacgcttga aagattcttg
    36901 ccagcctgca tcacatgaga gttcggatcg gcgacaacga gcaatgcagt accagaaatt
    36961 ccgagttgag ccaatacatt tgccagcaat tttgtctttg cctctgcgat agacagctca
    37021 gagactacaa caacgttgcc ctcagacaac ttggccgaga ggacactctg aagggcagcc
    37081 cgatacttct tctttggcat tccaaacgcg tagcttcgcg gctttggacc aaaaacggta
    37141 ccgccatgtc gccagacagg ggaccgtaaa gaaccggctc gagcacggcc agtgtgcttt
    37201 tgcttccaag gcttctttcc cgatccgctc acctcaccgc gacgcaaagt ggaagcagtg
    37261 ccctgacgat cgcaggccct ctgcattacc acggcttcgt gcacaagcga accatgcggc
    37321 ttgcacccga atacttcgtc cggcagatct acactaccga ctttcttctt tttcgaatca
    37381 accacatcaa cgatcggcat agctcaactc ttttttgact tccgcacaac tagcagccca
    37441 ttcgcaccac caggcactgc tccgcggacg aacaacaggt tttcatctgg acgggcgtca
    37501 atcaccttca gacgctgaac cgtgacacgc tcatccccca tatggccagg caaggcctta
    37561 tttttccaga cacgagatgg ataggagctc gcgccgatcg aaccaggagc acgatggaac
    37621 atggaaccat gcgtctctgg accaccggca tagttgtgtc gtctcacgac accttgaaag
    37681 cccttaccct tcgaaacacc aacaacatca acccaatcac ccttcttaaa catatcgacc
    37741 ttcacggtcg cgccgactgc gacttcccca gttttcggga attcacgcag ccaccggctg
    37801 ggaggagcct gatgcttctt caaatgtccc agttcaccgc ctgagagtct ggactccttc
    37861 acttcaccga atgacagctg aacggcttcg taaccgtcgc gctccttggt cttaatggca
    37921 accactcggc acggaccagc ctcaatgacc gtcactggct ccagaacgct ctcatcataa
    37981 atttgggtca tccccaactt tttacctaac aatccgtttg tcatggtctt cctgtcagct
    38041 caaaaaaggt cgagacttta aaccctcaga gcttaatctc cacatctaca ccagccgcca
    38101 aattgagctt catcaatgag tccatggtct ccggcgtagg ctccatgata tccaacagac
    38161 gcttgtgcgt acgaatctca aattgttcgc gggacttctt atccacatga gtcgaacgct
    38221 gcacggtgaa tttctcaatt cgagtcggca atgggatagg cccgacaacc cgcgcaccgc
    38281 tacgcctgac cgtctccaca atctccacca ccgactgatc aagcacgcga taatcaaaac
    38341 cacgcaacct gatacgaatt ctttgatcga ctttcacgct caactcctca catgccggcc
    38401 aacagaccag gacatcctaa gctagaattt ccgtaacgac gcccgagccg acagtcttgc
    38461 cgccttcgcg gacggcgaac cgcaacccct gatccatcgc aatcgggctg atcaattcgc
    38521 ccgtcaccgt gacgttatcg cccggcatca ccatctccac acccgccgcc aacgtcacga
    38581 tccccgtcac gt
//
LOCUS       DAOQPD010000028        37447 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_454_length_37447_cov_19.573786, whole genome shotgun sequence.
ACCESSION   DAOQPD010000028 DAOQPD010000000
VERSION     DAOQPD010000028.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 37447)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 37447)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37447
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_454_length_37447_cov_19.573786"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            18..800
                     /locus_tag="PK063_08660"
     CDS             18..800
                     /locus_tag="PK063_08660"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97160.1"
                     /translation="MRNVLALGAAVLFISSVGVAGAQERLPQSSSGSGFGVGNSVGDV
                     SGNSGRTAAFDRTAFMERLSQPETIYGRVLAIDIPGGKLHLETGGSSHDEGRAGQGAM
                     SSLTTYLDAQTNMDQIRVLNAGDDISLQVVEAPNQRADLGIYGSGRKMVREVYLMRGN
                     EKLAGFGGLGQRPAPSTERGIETNSATNTGGPVGGVFPGTVTSGVITTTVGEFTGTAP
                     CWNCEPQPGWGYQTVAPETKVQNKSDYGTDGAKPNLQKGWTN"
     gene            952..1212
                     /locus_tag="PK063_08665"
     CDS             952..1212
                     /locus_tag="PK063_08665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA family protein"
                     /protein_id="HMZ97161.1"
                     /translation="MSNSSAHVHTPDEELDLRGVICPYNFVKTKLKLESMAPGQLLLV
                     HLDDGDPIRNVPRSVSDDGHDVVSQERAEQSFRVMIRKRADE"
     gene            complement(1217..1966)
                     /locus_tag="PK063_08670"
     CDS             complement(1217..1966)
                     /locus_tag="PK063_08670"
                     /inference="COORDINATES: protein motif:HMM:NF012799.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HMZ97162.1"
                     /translation="MRRERSQEKCTQSGTGSGTLFIVGVPIGHPDDLTVRALSTLRHV
                     DLIAAKNPQSTQALLSHHGIHAVVTTYDRNNAAEKAPVLLQRLKQGRDIALVSDCGMP
                     AVYDPGRVLISAASKAHVAIEVIPGTSVVVAAAALCGMDGDSFVFEGRWAGGLRHMTH
                     RLHSMRAESRTMIFLPPAKKLPALLSLILHTLGNRRVVIARDLTKDTQTVVRGRVRTV
                     LARDSFHNSRSQITLIVEGMKGKGKTARGPA"
     gene            2032..2838
                     /gene="ccsA"
                     /locus_tag="PK063_08675"
     CDS             2032..2838
                     /gene="ccsA"
                     /locus_tag="PK063_08675"
                     /inference="COORDINATES: protein motif:HMM:NF013725.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis protein CcsA"
                     /protein_id="HMZ97163.1"
                     /translation="MSSVFFMLTMGLYFVSTVCYLAYLLRRAETLSKVSLGITAAGFA
                     THTVALVARMADSSQAQLPTFHEALSFFSWMLILVFLAVEFRRQLHVLGSFIVPLALV
                     SLVTAAAFRSDGASSLQPVFKTLWVHVTLSMLGTVGFAIAFVAGVMYLIQDGLLKSKR
                     FNVLYAKLPALDYLDHLNQQSIVMGFPLLTLGIISGAFSAEIVRGTYVNWNPEQTWAM
                     VTWGFYFAVLVGRLTIGWRAKRAAYLTIIGFAGVILTLIGVVLKSHGSVS"
     gene            2838..4244
                     /gene="hemA"
                     /locus_tag="PK063_08680"
     CDS             2838..4244
                     /gene="hemA"
                     /locus_tag="PK063_08680"
                     /EC_number="1.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008883 - glutamyl-tRNA reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA reductase"
                     /protein_id="HMZ97164.1"
                     /translation="MHVIVVGLSHKTAPVEIREKLAVPESRLREALSRLCTYQGVREG
                     LLLSTCNRVEVYAVVEDLESGYGRVQEFLADTHLSLSSEHLTPHLYWHAGDRAISHLF
                     RVASSLDSMIVGESQILGQIKDAFEVALTHKASGLLLNKIVKKAISVAKRVRTETKIA
                     ETAVSVSYAAVELAKKIFSNLTEKTVLLIGAGEMAKLAARHLIANGVRQVRITTRNFQ
                     HGLELAQKFNGTAVPFEDYKTELAGADIVLVSTGASHYLVTADDVQRAMRQRMSRPMF
                     LIDISVPRNIDPAVRPIDDAFLFDIDDLHMRVEQNREDRLREAAKAEQMVVEEVAVLG
                     QWLQSLEVTPTIVALRGRTEEIKRREVDKVLARLAHLSPEDRAAVEALASAIVNKMVH
                     GTMVTLKAEATSSSGAAYVDAARRFFSLEDAPAAYPPAQTEVQEVSEDSSDGNGANRF
                     SEASLVQHTTKEQSRRVS"
     gene            4331..5260
                     /gene="hemC"
                     /locus_tag="PK063_08685"
     CDS             4331..5260
                     /gene="hemC"
                     /locus_tag="PK063_08685"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004418 - hydroxymethylbilane synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HMZ97165.1"
                     /translation="MSRALILGTRGSKLAVHQSEWVQARLQELVPGLTISLKRIQTSG
                     DKILDVPLAKIGGKGLFVKEIEDALLSGEIDLAVHSMKDVPTALPDGLDILCVPPRED
                     ARDALITRDGCRLDELKPGARIGTSSLRRQSQLLHHRPDFVIEMLRGNLDTRLRKLRE
                     GQFDAIVLAAAGLRRLGWNAEITEYLPVELSLPAIAQGALGIEARRDDSFVRDVLARF
                     EHRPTRITVTAERALLHRLEGGCQVPIAAHALLDGETLKLDALVASVDGKRVIRQHIN
                     GLATEAHQLGTTLAERLLSAGGDVILKEIYGRA"
     gene            5260..6828
                     /gene="cobA"
                     /locus_tag="PK063_08690"
     CDS             5260..6828
                     /gene="cobA"
                     /locus_tag="PK063_08690"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004851 - uroporphyrin-III
                     C-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0019354 - siroheme biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HMZ97166.1"
                     /translation="MVKTTRKGTVYLVGAGPGDPKLLTLRGKECLEQADVVLYDYLAN
                     EALLQHVPRTAERLYVGRRGRGHYRDQSEINRVLIDQARAGKCVVRLKGGDPFVFGRG
                     GEEAEAVAAAGLDYEVVPGVTAAVAAPAYAGIPVTHRTLASTVTVITGHEDPTKERSS
                     IEWTRLATVHGTLVFLMGMTNLPKIVQCLRAEGKDGSTPVAVIRWGTRVSQRTVVGTL
                     DDIVEKAAAAHMEPPTVIVVGEVVRLRPQLNWFEQRPLFGKRILVTRPKPQAAEFSDL
                     IQAQGGEAVECPTIEIAPPEDQAPLDAALARLSTYNWLIFTSVNGVGPFMTRLLSTQR
                     DVRALAGLTICCIGPRTAEALAAYGLRADVIPEQFQAEGILDSLAGRHLRGAKVLIPR
                     ALVARELLPEQLRAQGAEVDVVPVYRTILPTVALDHLVGQLGAGEIDVISFTSSSTVR
                     NFVGLFPSKDELLRLIGETTIACIGPITAATAREAGLTVHVMAAENTIPALAEAIVRH
                     VEHQRDRRPASANR"
     gene            6881..7273
                     /locus_tag="PK063_08695"
     CDS             6881..7273
                     /locus_tag="PK063_08695"
                     /inference="COORDINATES: protein motif:HMM:NF012780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HMZ97167.1"
                     /translation="MVPVKSFMVPKDKFITVERDVDVRTAGRVMRDRNIGSLFVTNGK
                     DVIGIITDTDMVRRVVATGADMTKTTVEQIMSAPLVTIEEHKTLLDANDLMAQTHLRH
                     LGVTKDGQLVGMISVRDLVVFLTNLPRK"
     gene            7278..8261
                     /gene="hemB"
                     /locus_tag="PK063_08700"
     CDS             7278..8261
                     /gene="hemB"
                     /locus_tag="PK063_08700"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0004655 - porphobilinogen synthase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HMZ97168.1"
                     /translation="MAFPMQRMRRTRETEPLRRMVRETTLSPSDFIYPVFVTEGQGRR
                     EPINSMPGQCRVSIDLLIKEALEVKSLGIPAVILFGIPDRKDERGSSGFDPNGIVQRA
                     IRALKEQVPELVVITDVCIDEYTSHGHCGIVRNGKIVNDETLDCLRAMAKTHAEAGAD
                     MVAPSDMMDGRVAAIRDELDRAGFVDIPIMAYAAKFASCFYAPFRDAANSSPQFGDRQ
                     SYQMDPANKREALREIDLDVEEGADIIMVKPAMPYLDVISAARERTLLPIAAYQVSGE
                     YSMIKAAAQAGWLDERRAMMESLLSIKRAGAEIILTYFAKEAAALLQSRHA"
     gene            8258..9220
                     /locus_tag="PK063_08705"
     CDS             8258..9220
                     /locus_tag="PK063_08705"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: protein motif:HMM:NF004160.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HMZ97169.1"
                     /translation="MKISRGLTPSIARPYSVVTIGNFDGHHHGHRALLDRVVSTARRE
                     SGTALVLTFDPHPVKILAPQVNLMFLTTPEEKLARFEAAGIDEVVFLEFTTAFAALSP
                     AQFAKQVLCDGIGTRELFVGEHFAFGKGRAGRIADLLELGAQLGFRVHPTPPVTIDGE
                     VVSSTKIRQMIQAGDLQKAIRFLGRPYGIEGRVIPGAHRGTELGWPTANLRLPEGRVI
                     PPDGVYAARVLWNGRALDSVVYIGTRPTFGAGERLLEVSILDERLELYGETIRVELLG
                     FVREDRVFASAEALSRQIELDVDAARIQLREAALDTVSPLHSQS"
     gene            9224..10708
                     /gene="tilS"
                     /locus_tag="PK063_08710"
     CDS             9224..10708
                     /gene="tilS"
                     /locus_tag="PK063_08710"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: protein motif:HMM:TIGR02432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HMZ97170.1"
                     /translation="MAGPSTATPHPLHNKVIRALRTRALLQPGQSVLVAVSGGPDSVA
                     LLSLLHELAPAWNFSLTVVHCNYGLRGAESDGDASFVAELCRRLKIPCVVKALQIPAR
                     EPGRSSSLQARARELRYQLFRDLVTELGIERVALGHTADDQAETVLLRMLRGAGLRGL
                     GGMPHRRGNLFVRPLLTVTRREILSYLETKSLSFRTDSSNATSVYLRNRVRHELLPVM
                     QSLAPATVPLLARQADIVREDDRLLERLAARRLVRATVNRDSQTLALDRAVLLKEEPA
                     LQRRMLRQAMRSLSPLAIGVRGDVVLSLLASLSAGRSGGSWTVGSLVVTSEQGLVRIA
                     VGDPAGPKTESSSQSASGVALQTVTLSSLPCEVPWPPTGALIRISVVTRERGMALLKK
                     PSSTIAIFDADRLLLPVTVRSWRQGDYFFPAGMAGRRKKLQDYFTDAKLGRSMREHIP
                     LLLSREHIAWIVGQRIDARFAATASTTRFIVARVTHPVRRKGVL"
     gene            10711..11262
                     /gene="hpt"
                     /locus_tag="PK063_08715"
     CDS             10711..11262
                     /gene="hpt"
                     /locus_tag="PK063_08715"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HMZ97171.1"
                     /translation="MERIFGRPIVTQEQMRTRIRELGRQIASDYAGKELVLVGVLKGA
                     YAFYADLARAIRIPMRVEFIVVTSYGAGKRSSGKVKLISDLTEPIVGKDVLLVEDIVD
                     SGLTVQYLMKTLSRRKPRSLKVCTLLSKPERRQVEVDLEYVGFKIPNKFVVGYGLDYR
                     QEYRNLPYLAALDQGEEGEQESA"
     gene            11350..13164
                     /gene="ftsH"
                     /locus_tag="PK063_08720"
     CDS             11350..13164
                     /gene="ftsH"
                     /locus_tag="PK063_08720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HMZ97172.1"
                     /translation="MNSRVKNLLFWVVVGLFMILLFNLFSVPTHAPEDEVIFSDFMAK
                     LDKGEVMKVTIKANHISAILKDQSRIRTYTAEYPELVKHLREKDVQIEARPPDESPWY
                     ITFLVTWGPFILFLGLWFFLMRQMQIGGNKALSFGKSRARMLTEERKKVTFSDVAGIE
                     EAKEEVLEIIEFLKDPRKFQKLGGRIPKGVLIVGPPGTGKTLLAKAIAGEAGVPFFSI
                     SGSDFVEMFVGVGASRVRDLFEQGKKHAPCIIFIDEIDAVGRLRGAGLGGGHDEREQT
                     LNQLLVEMDGFDTTEGVILIAATNRPDVLDPALLRPGRFDRQVVVNRPDLRGRSEILK
                     VHTKKVPLSTDVELEKIARGTPGFSGADLENLVNEAALWAARLNKKEVELIDFEMAKD
                     KVLMGAERKSMVLTDEEKRTTAYHEAGHALMAKLLPGTDPVHKVTIIPRGRALGVTMQ
                     LPTDDRHNYSKDFLYNNLAILMGGRVAEELVLHDVTTGAGNDLERATDLARKMVCEWG
                     MSEKLGPLTFGRKEEEIFLGRELGSKRDFSEQVALEIDHEVRRLVTENYERAKRILTD
                     NMTSLKALAEALLEKEVLDALEIDQILIQGSSSQTVPA"
     gene            13352..14251
                     /gene="folP"
                     /locus_tag="PK063_08725"
     CDS             13352..14251
                     /gene="folP"
                     /locus_tag="PK063_08725"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HMZ97173.1"
                     /translation="MTLDTPSPFRPVVITAGSHNITIQSNPLVMGVLNVTPDSFSDGG
                     AYSTVERAVDHARQMQADGADIIDIGAESSRPGADPVEEGEELRRLIPVVEAVREAVS
                     LPISVDTTKAAVARLAIQAGALIVNDISALQGDPLMAGLVAETGVAVVLMHMQGTPRT
                     MQRSPRYGNVVEEVTVFLRQRAQEAIARGIRPTQIILDPGFGFGKLQEHNLHMLAEFD
                     AFTKLGYPVLAGVSRKQFIGNLIRQPVHEREFGNAGAVAVAVLKGAHIIRVHDVRAMK
                     ETATVVSAISRHARSSSVEVSNA"
     gene            14244..15593
                     /gene="glmM"
                     /locus_tag="PK063_08730"
     CDS             14244..15593
                     /gene="glmM"
                     /locus_tag="PK063_08730"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HMZ97174.1"
                     /translation="MRKLFGTDGVRGVANLEPMTSEIAMQLGRAAAHIFMRRAGRHQV
                     VIGKDTRLSGYMLESALTSGICSMGVDVLLVGPLPTPAIAFLTRSLRADAGVVISASH
                     NPYQDNGIKFFSNEGFKLPDEVEARIEQLIISDEIKHLRPTADAIGKAYRIGDAEGRY
                     IEFVKRSLPRDLDFQGIKLVVDCANGAAYKVAPAVLRELGADIEVIANTPDGMNINDH
                     CGAVHPERLQEAVRRNGAHIGIALDGDADRAIFVCEQGHIVDGDHVMAALGLDLHGQG
                     RLASQTVVGTVMSNFGLELAMKKAGIQLMRTPVGDRYLMERMLADGYNFGGEQSGHFI
                     FLDHNTTGDGLISALQILSLMKRTGKPLSELAKAMTAVPQILLNVKVKHKPDLNQIPD
                     IQQAIKTAEATLNGSGRVLVRYSGTEALLRIMVEGERDATIREVADYLADIVRARIG"
     gene            15620..18151
                     /locus_tag="PK063_08735"
     CDS             15620..18151
                     /locus_tag="PK063_08735"
                     /inference="COORDINATES: protein motif:HMM:TIGR00361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HMZ97175.1"
                     /translation="MLPFLTIIFILGIALGSYLQYFPLSIGLFFFASTIAAVLAERRG
                     LLTAGHSSLRLACLFCGCLYWSLFSWSTSHVPVPDRPAALPSTIDGTIVESVRHAPGR
                     LTALMQVTATDDPDLATPFSLRLTWRDPDRDLQRGLHIRLRTRVHAPSGTLNPRGFDY
                     AAYLEAQGVDAVGSVSGAGAIEVLGADEGLLAYPISSRIDAWRSQVRNAADALPQPAR
                     GLFLSLTIGEQGFLAPEVREWFMTTGTVHILSISGSHLGLIALLSFALVRKACLLLPS
                     MLLLGLSRWLIPSRLAALLTLVPVLGYTLLAGAETATIRSAIMIIVGLWTIWLGTPQY
                     LLHALAAAAGLTLLVHPAALYDISFQLSYVSVWVLALALQRQQSIDELPLPQKSLAGR
                     TFYWLQESIRLTAWVTLATLPLVACYFNQVSWMGIFANLLMVPFVGFILLPISLLSAV
                     WVIVSHSSTLPGAGLIELFAQAVTVPTQWLAGLPGAEWFVAAPTVPLMALFYLLGWAM
                     LTDRPAHAPLLVKRAMAFGMACLILWWLWSPRPFTREGQVRITFLDVGQGDSAVIELP
                     KGEVVLIDGGATYERFDMGRSVVAPFLWNRGIRTIDHVIATHPQLDHAGGLAWILAHV
                     QVENFWTNGVTRSEEFWRKIERTLARRHLQAQVAEQGRRLVDDAECDIAVLNPPPGRN
                     ASSAGKQQSLNNLSVVTELTCGGRRMLFTGDIEREGLARMVQSGHLRHIDLLKVPHHG
                     ALSSLDREWLSSVQPDIAVVSAGRRNPYGHPAGEVIAAYESLETQLWRTDQDGAVWAD
                     LDLNKQSLTMHSTREWQLQPALIPIPQWAIEQDNFHRLWRRWNWN"
     gene            18463..>18752
                     /locus_tag="PK063_08740"
     CDS             18463..>18752
                     /locus_tag="PK063_08740"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97176.1"
                     /translation="MMANRLLFLAPVPPSDHQGGGPLRMLHLLRFLGSRFHVDLVAPA
                     VDGWENAQNSLQGVCAETTFVPPQGPGLLDRLGRVSPYVKDRALASVVRERLA"
     assembly_gap    18753..18852
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <18853..19805
                     /locus_tag="PK063_08745"
     CDS             <18853..19805
                     /locus_tag="PK063_08745"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HMZ97177.1"
                     /translation="SPYVKDRALASVVRERLASGVYGAVHVEKLGLIASLPTQLAIPV
                     VLDIWSYGLPSPLGIFKSGGGTTGRPKPFVRRLKLGLYDRWCWPLTSCVTVVSEEDRI
                     RCEGAHPGQRVIVVPNGVDCQAIRPKSDHALTSPVLLFSGDMGAEPNVEAATVLATEV
                     FPAIRREFPKAELRLVGRNPDPRVARLAGPGIMVTGAVPDMQVHLRAATIYVAPHFTG
                     PATRTKLLEAMAAGLPIITTSLGTEGMKVQPGRDLLVADQPADMIESIQTLLASQPDR
                     ERFAQAARHMAEVWYDWSRCLWPLEPLYQNLLAPKPAVAC"
     gene            19963..21030
                     /locus_tag="PK063_08750"
     CDS             19963..21030
                     /locus_tag="PK063_08750"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF013227.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HMZ97178.1"
                     /translation="MTLIPHSKPSLGQEELRAVTEVLRSGQITAGPMVAQFERGIAAY
                     IGLHGGVAVSSGTVALELALRALGVGHGDNVILPSYVCSAPWLAVQRVGAQARLVDIN
                     PTTYNLDPQKVRKARTSRTRAVIVPHMFGLPADLTSLQSLDIPLIEDCAQTLGAMEQG
                     RAVGSVGTLTVCSFYATKLLCTGEGGMVLSNDEALLERVRALREYDKAPSLNSAAGNC
                     KLTDLQAAIGVAQLNQLGEFLDKRSALAALYRDMLSPELFTMPVVPAGRTHVYFRFVV
                     RLMKGLQSADDFTDYLSRLAHRGLQCRKPVFRPLHRYLDLPDFPASDEADASAISLPI
                     HPSLTEEAIRQAAHILQEELH"
     gene            21156..22220
                     /gene="mtnA"
                     /locus_tag="PK063_08755"
     CDS             21156..22220
                     /gene="mtnA"
                     /locus_tag="PK063_08755"
                     /EC_number="5.3.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046523 -
                     S-methyl-5-thioribose-1-phosphate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-methyl-5-thioribose-1-phosphate isomerase"
                     /protein_id="HMZ97179.1"
                     /translation="MVPTVEWKEGAVRLLDQSRLPSQVEFLDCRDYRSVAQAIRELKV
                     RGAPAIGVTAAMGVALGAQSVDADEYSSFVKQVDAICDHLAASRPTAVNLFWAIARMK
                     QKLASLKGMPIAEIKRELIRESQSILDEDIALCKAMGRHGATVIQNGQTILTHCNAGA
                     LATAGYGTALGVIRAAWEQGKQIRVIADETRPVLQGARLTAWELMQDKIPVTLITDNM
                     AGSLMRQGNIQVCVVGADRIAANGDVANKIGTYSVAVLARAHGIPFYVAAPYSTIDLA
                     TKTGAEIPIEERNPLEVTSIHGSHPVAPSGVAVYNPAFDVTPAELITGIITERGIFKP
                     GELAGAFGTSRPPIKSGNVS"
     gene            22375..22794
                     /gene="ndk"
                     /locus_tag="PK063_08760"
     CDS             22375..22794
                     /gene="ndk"
                     /locus_tag="PK063_08760"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0006165 - nucleoside diphosphate
                     phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HMZ97180.1"
                     /translation="MSERTLAIIKPDAVKKDAIGDIINRYEKAGLKPVAMRLMHLSKA
                     TAQGFYAVHKARPFFDSLCTFMSSGPCVVLVLQGDNAVKKNRELMGATDPAKAENGTI
                     RAAHGANIEFNAVHGSDAPETAKFEIGYFFPEMELVG"
     gene            22826..24346
                     /locus_tag="PK063_08765"
     CDS             22826..24346
                     /locus_tag="PK063_08765"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97181.1"
                     /translation="MQTRRPFSGRRASLPLVILLMAIGSGCAGPPAVVPVAQPIENPV
                     VEAETRLWYQASSAFSDGRYSAATHLYERYLTTYPKSRRANEAHWELAQSYEQMGEAA
                     GALKEYRILAGPEGAPLSTQSAYAERALHRIEALRNQSSLPGARSGHTALYVSFSNLP
                     PMAQVETWIQRLSAQGVSAILMDASLESSFTRPPAPTGPPPSSPLPKLPAGALFSTSQ
                     GPVMTDWFSVMVPQAHELGISVFAVIDLFHAPLSDHRQESRTLLYDPTRRKVHSWTQF
                     DLLAPPVQQEVAQLLADLLRSGVDGMVIRARAENSFAYEVSDGVLRQFEAQVRQPASE
                     VAQALRERMSVRQDAGALASDKTLWRWVGWKSRQELDVLARLKKYLQKAVPRLRMVLE
                     IHPEALSNPTSALVNYGEDAAEARRRGFDLLLGGPSREASDVRTFGGSFKGWSRDVIQ
                     SEKGEPQTLPQGWVLLRTPTEHGGGMFMGLAQQADELRTPDIRHLVFVPDAPPAIP"
     gene            24487..24873
                     /gene="gcvH"
                     /locus_tag="PK063_08770"
     CDS             24487..24873
                     /gene="gcvH"
                     /locus_tag="PK063_08770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HMZ97182.1"
                     /translation="MIPSNLRYHQEHEWVRAEGQQATVGISHFAQDALGDIVFIDLPK
                     VGAKVTAGQQIGEVESTKTTSTIYTPVSGTIAKINTELKDHPEAVNADPYGKGWMAVI
                     DLTTPGEVDKLMTAAQYEEFLSKQKH"
     gene            24962..26389
                     /gene="lpdA"
                     /locus_tag="PK063_08775"
     CDS             24962..26389
                     /gene="lpdA"
                     /locus_tag="PK063_08775"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA];
                     GO_process: GO:0051068 - dihydrolipoamide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HMZ97183.1"
                     /translation="MSKHLAILGAGPGGYVAAIRAAQLGARVTVVENQALGGVCLNWG
                     CIPSKALLSVVELGDKAKKAKDFGLLLNGPVAYDPAIMVARKNKVVSTLVKGIATLFK
                     TWNIEHVEGTGELVDARTIRVTKPDGTTLQVAADGIIVATGSSWPNLPLFPIDGTQII
                     TSKQALDLTRIPASLLIVGGGVEGCEFASLYSGLGAQVTLVELVPRILPLEDEEISQM
                     MERELKKRGVDIRTGVTVDQIVRQSDVVTAHLRDGLSLNVEQVLVSVGRGFNSRGIGL
                     EKAGVQVGSRGEIVVNERMETNVPGVYAIGDVVGKAMLAHVASQQGKVAVENFMGHAR
                     AIDYDVIPTGIFTLPEIGRVGLTEQQARDRCVGAGKDPQQSVKVGRFRYGGLGKAQAT
                     GDIQGLVKVVVDTESDRILGVHILGAHATDLIHEAALAMHLGATVARAAEMIHAHPTL
                     AEGLMEAMEDVHGHAIHLARKPATT"
     gene            26386..26934
                     /locus_tag="PK063_08780"
     CDS             26386..26934
                     /locus_tag="PK063_08780"
                     /inference="COORDINATES: protein motif:HMM:NF024245.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HMZ97184.1"
                     /translation="MMQSLLIKVAMLAVTLGSLVWIASVTPVTKVMPGQPQLLPKHSV
                     TTVSSPPPVEVPATRPALASVSQAGTPSRRQVAMPIEESESASARVSEKASTDSPSAR
                     QAGARQVDLNQATLSELEALPGIGPKLAQRVIEHRDENGPFRSVDDLRQVKGIGRKKF
                     DRLRPHVLVTNTKSLARHKGTL"
     gene            26931..28148
                     /gene="tyrS"
                     /locus_tag="PK063_08785"
     CDS             26931..28148
                     /gene="tyrS"
                     /locus_tag="PK063_08785"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HMZ97185.1"
                     /translation="MTPLAQQLDLILRGIVEVIQQSELESKLARSIKENRPLRVKAGF
                     DPTAPDLHLGHTVLIHKLKHFQDLGHQVIFLIGDFTGMIGDPTGRSETRVALSKEKVL
                     ENAKTYERQIFKILDPAKTQVEFNSRWMSTMTADGLIELSAHYTVARMLEREDFHKRY
                     TEGTPISIHEFMYPLIQGYDSVALKADIELGGTDQKFNLLMGRDLQRDYGQEAQAVIT
                     MPLLEGTDGVRKMSKSFGNYIALEDQPADMFGKLMSISDTLMHRYYELLTTENLAGVK
                     AAHPMDAKQGLAEQIVARYHGADAGREARTAFQQKFQAREFPEQPDAHVVLTPSDVKD
                     ASAPSIGLVDLIAKTGLVPSKSEARRLIVQGGVEINEQKMTDANGAVPLLVGQLLRLR
                     VGRRKFAVAEYKD"
     gene            complement(28690..29115)
                     /locus_tag="PK063_08790"
     CDS             complement(28690..29115)
                     /locus_tag="PK063_08790"
                     /inference="COORDINATES: protein motif:HMM:NF012422.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HMZ97186.1"
                     /translation="MDWQAVRVQQMVSSPQGGVLLRGFGVPDELPHECGRLLLLIEPI
                     IEQGEADSFSSREQIRLTHREGAVARYLAAGLTNKEIANHLHLSEYTVKDHVKRLMRK
                     TQTTTRTATVSRLLLQYPSLSKAKVTDGIMGTIFAKQAV"
     gene            29748..37088
                     /locus_tag="PK063_08795"
     CDS             29748..37088
                     /locus_tag="PK063_08795"
                     /inference="COORDINATES: protein motif:HMM:NF015497.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat-associated core domain-containing
                     protein"
                     /protein_id="HMZ97187.1"
                     /translation="MRSTYQPIRRLLVALAALLLLDPGHGLDAKETDTETPIGAVGGS
                     IHGDPFTGTATASIPIEIPPGRNGVQPGLQLVYSHSNGNGWIGMGWKLELGSIERQSR
                     FGVDYAKNDYTIQMSGMSTELVQAPLPASSDEYRAKFEGSFSKIKMLSNGGFEVTDKK
                     GTKYLFGQSGVSRVSHPTDSSKIYKWLLDRVEDRDGNFMTATYSADQGQEYLSQITYT
                     GNGAAQPGNTIKFYLESRPDGQTLYTANFQVITAQRLKTIEVLSGTTRLRAYKLAYST
                     SASTGRSVLTSVQQFGKDAVLDGSFTVTGGTSLPPVSMTYENESMSLGSDQLWGSKSY
                     GIGCAAASNCRPNFAYVDMNADGRTDFIYQRSDIDEMHVLLSTGSGFGSDTNWGMKSF
                     GIACAGASSCQPAFSYADMNGDGKTDFVYMRSDLDQFRVMLSTGTAFSTDTVWGSKSF
                     GIACAGASNCRPNFAFTDVNGDGKADFVYQRSDIDELRVLLSTGIGFSADTNWGMKSY
                     GIACAGASNCQPNFAFTDLNGDGKADFVYQRSDIDELRVMLSTGTAFGPDTSWGVKAY
                     GIACAGASNCIPNFTFADINGDGKADFVYQRSDIDELRVMLSTGTGFATDTAWGMKAY
                     GIACAGASNCRPAFGYFDVNGDGKADFVYQRSDIDELRILLSTGSAFRPDAVWGMKGF
                     GIACAGAMNCQPSFSYVDTNGDGKGEFAYHRDATDQIRVLPSSPDGILLATMTNGTGG
                     AAITTYAPSTQFSNTLLPYTTRLLTSTVTCDNWGGSSCVGLSSTTTYTYSGGYHHLAE
                     RDFRGFNYAKVTGPVGPTGEQLITETWFHQGNDVAVDTNNPNVANGYTKGMPYRSKVT
                     DATGKVYSETTTTYIADVDGAAPFFTPVAQVDASIENGAKQTRSVFAQYDAYGNVLRE
                     DQYGDLATTADDRTVVRTFANNTTDWLLGFPTSETSYAGIGTTTQVAQTNLYYDGTTS
                     CATASVNQVPTKGHVTRTVRWLNGGTSPETRMAYDAFGNLTCTRDALGQTSTVNYDST
                     NTFVKTATNPLGHVVTTQYYGVDGVLLDKGLYGQVKSLTDSNSQTTTSEYDALGRKSK
                     TTTPDGLTTTVIYNYGPGFTVGTQHVLSSTSGAGLATALTSASYFDGLGRGVKKETPG
                     PDSKTIVTEVQYDSRGAVRKKSLPYFKTLESVTGRWATTSYDALGRVVRMDSPDGTRG
                     LACFTDWVTVTIDAADHRKRETKDAYGRTIRVDEYQGTASTCDTTVGTPYATTTYQYD
                     VQGNLLSVTDARGNVSTMTYDTLNRKTAMHDPDMGNWSYVYDANGNLTKQTDAKAQIL
                     WFRYDALNRRVQKDFTTQKALGAGDVRYTYDGTTNNRKGRLQQVVDASGTVVFQYDGL
                     GRISQTDKTLDGTTYTTQSTYDGLGRLLTVTYPSTPSKTISYAYNGPVLDKVFEGTTT
                     YIQYTNHNALGQAGTTTYGNGVSTTTTYANANNTICSQQNFRLCTLVTNGPGSGGGGG
                     GTSTTYSALADFSGTQGSRGWYYLSSTGTQLTWNGSYWTGTDGYLGLWNDGGHPGNST
                     DAVRRWVAPSAGSIQITGNTFDGDTSCGTDGVVVTIKKNGAVLWTQTIAAGNTTGFTF
                     NLSNSVVVGDQIDFVINKLTTSSCDNTVFTPTIVLTTAGGGSGPLLNGTYTAPASTVN
                     LSTEGTVDWTHWGLSTATSFNHKSGVTSQISNFSAVGGGVAGQYSDNLVGYTWTGGTP
                     TASATNSTTGLYIVGVNKGFQFTVPADTTQRTVKVYVSAWGAQGKMEAFLSDGSAAGY
                     SDTSLSDPGLSSSGAARVYTFTYRAASANQTLTLRWTNLVQNDPAGGNVTLQAATLVT
                     TSGGGSSGTAYQDLRYVYGLNGNVNDIYDNLVPGGAGDQHLSYDGLDRLTLASGPYGT
                     NGATASLTCTYDELGNLTFNSQVGTYAYPASGSSSVRPHAVTTAGSNTYSYDANGNLT
                     SGAGRSLTYNLENKPLTVVISGQTTTFVYDGDGGRVKKIAGTTTTRYISKFYECDNTS
                     CSRMVFAGGQRIATIGASGSIYYYHTDHLGSSSVITDSAGAKAQAVTYFPYGATRTNN
                     STATPAIDVPYKYTGKELDSSTNLYYYEARYYDPTLGRFLSADTLVPNPLDPQSLNRY
                     SYVHNNPFKYTDPTGHFKINVGKFLRRSLGDLGTGIAGVLGQTLGNALYWSGNPILGS
                     LVQGLGTAMLTQSKSGRYVLAGEIIVTTVVLYSVCPGCDGGAAASFIGPMTAAQASAG
                     ATAASVWGGAAAGAIGGAALGGYSAAKNGGDISSGVLFGATIGAASGALGGGLAPAPG
                     MFGTNLHGWLAQTIAKGLITNFGSGAISSYAGGKGNIGNILMGATMNAALGTATTPAS
                     DLFWGQMVPEVMGYLPATDMEPYYINNAEGVPVRGPEPYAPFNTDLGKRLTGMMGDAG
                     ASTFGEVYGEKLGDIIHGRPIHIP"
     gene            complement(37190..>37447)
                     /locus_tag="PK063_08800"
     CDS             complement(37190..>37447)
                     /locus_tag="PK063_08800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HMZ97188.1"
                     /translation="QLDFIRPGKPVENAFIESFNGRLRDECLNVHQFASPAEAEAIIE
                     AWRVDYTQRRPHSSLGHLTPSEFVSQRHPSLIGPNSTAQSK"
BASE COUNT         7669 a        10121 c        11352 g         8205 t
ORIGIN      
        1 cactaaggag gcagcacatg cgtaacgtgt tggcacttgg agctgcggtg ctttttatca
       61 gctccgttgg tgttgcaggc gcccaagagc gcttaccaca atcctcatca ggatcagggt
      121 tcggtgtcgg caactcagtc ggagacgtgt cgggcaactc cggccgcacg gcagcgtttg
      181 accggaccgc cttcatggag cgtctctcgc agccagagac catctatggg cgtgtcttgg
      241 ccatcgatat cccgggtgga aagcttcacc tcgagacggg tggcagctct catgatgagg
      301 gccgcgcggg tcaaggcgcg atgagctcgc tcacgaccta cctcgatgcc cagacgaaca
      361 tggaccagat ccgagtgctg aatgccggcg acgacatttc cttgcaggtt gtcgaagccc
      421 ccaaccagcg cgctgacctc ggcatctatg gatcgggccg caagatggtt cgtgaagtgt
      481 atttgatgcg tggcaacgaa aagttggcag gatttggtgg tcttggtcag cgtccggctc
      541 cgtccacgga gcgcggcatc gagaccaact cagccacgaa cacgggtggc ccggtgggtg
      601 gagtgttccc cggaacggtc acctctggcg tcatcaccac caccgtgggt gagttcactg
      661 gaaccgcacc ctgctggaat tgtgagccgc agccgggatg gggttatcag acggtcgctc
      721 ctgagaccaa agttcagaac aagtctgact acggcaccga tggtgccaag cccaacctgc
      781 aaaagggctg gaccaactaa gatttaggcc atctgaatgg ccgatggttg agcggggtgc
      841 ttcgcaagag gcaccccgct ttgcttttct gtcatgtgat gtgcttcctc accgttgcgc
      901 cagcagagta gtcttgatac gattaccgat cacttctcac tgagagcgta tatgtccaac
      961 tcatcagcac acgttcacac gcccgatgaa gaattggatc ttcgtggggt catttgtcct
     1021 tacaatttcg tgaagacgaa gctcaaactc gaaagcatgg ctcccgggca attgctcctc
     1081 gtgcatctgg acgatggcga cccgattcgc aatgtgcctc gcagtgtcag cgatgatggg
     1141 catgatgtgg tttcgcaaga acgtgccgaa cagtcttttc gtgtcatgat acgaaagcgt
     1201 gccgacgaat aaggcgtcat gccggtcccc gtgctgtctt gccttttcct ttcatgcctt
     1261 ccacaattaa cgtgatctgc gatcgactgt tgtgaaagga atcccttgcc aggacagtgc
     1321 ggacgcgtcc tctcacgact gtctgcgtgt ctttcgtgag gtctcgcgct atcaccactc
     1381 ggcgattgcc gagtgtgtgc aggatgaggg aaagcagcgc gggaagcttt tttgccggag
     1441 ggagaaaaat catggtgcgc gattcggcgc gcattgagtg aaggcgatgc gtcatgtgac
     1501 gcagaccgcc ggcccaacgt ccttcgaaca caaatgagtc tccgtccata ccacacagtg
     1561 ctgctgccgc aaccacgaca gacgttcctg gaatcacttc aatagcaacg tgtgccttgg
     1621 atgccgcgga gatcaacact ctgccgggat cataaacggc aggcattccg cagtctgaca
     1681 ccagcgcgat atcgcggcct tgtttgagac gctgcagcaa cactggcgct ttctcagcag
     1741 cattattccg atcataggtg gtgacaacag cgtgaatgcc gtgatgcgaa agcagcgctt
     1801 gggtagactg aggattcttg gcagcgatca aatcgacgtg ccgaagcgtc gaaagcgcgc
     1861 gaaccgtgag atcgtcggga tgtccgatcg ggactcccac aatgaacaac gttcccgacc
     1921 cggtgccgga ttgagtgcac ttttcttgac tccgttctcg tcgcatcgat ataatttcca
     1981 gttcccgaaa aaagtagctt tgcgctgaaa tgttgcgagg ataggggcag tatgtcgtcg
     2041 gtttttttca tgctcacgat gggtttgtat ttcgtgagca cggtctgtta cttggcctat
     2101 ttgctccgcc gtgccgaaac tctctcaaag gtttcgctgg gaattactgc tgccggcttt
     2161 gcgacgcata ccgtcgcgct ggtcgcccgg atggctgatt ccagccaggc ccagttgccg
     2221 acctttcacg aagccctctc attcttttct tggatgctca ttttggtttt tcttgctgta
     2281 gagttccggc ggcaactgca tgtgttgggt tcctttatcg tcccgctggc gctggtctct
     2341 cttgtcacgg ctgccgcatt tcgttcggat ggtgcgtcta gtcttcaacc ggtattcaaa
     2401 acgctgtggg tgcatgtcac cctcagtatg ctgggaactg tgggttttgc catcgccttt
     2461 gtcgcggggg tgatgtatct cattcaggat ggacttctca agtcaaagcg cttcaacgtc
     2521 ctctacgcaa aattgcccgc tctggactat ctcgaccatc tcaatcagca atcgatcgtg
     2581 atggggttcc ctctcttgac cctgggaatc attagcggcg cattttcggc agagatcgtt
     2641 cggggaacgt atgtgaattg gaaccctgag caaacctggg ccatggtgac gtggggcttc
     2701 tatttcgccg tgctggtcgg gcgcttgacc attggttggc gggctaaacg ggcagcctat
     2761 ctcaccatca tcggatttgc cggcgtcatt ctgaccctga tcggcgtggt gttgaaaagt
     2821 cacggttcgg tgtcctgatg catgtgattg ttgtcgggtt aagccataag actgccccgg
     2881 tcgagatccg cgagaagctc gccgttccgg aaagtcgcct gcgtgaagcg ctcagtcggc
     2941 tgtgcaccta tcagggggtg cgcgagggat tgttgctctc cacctgtaac cgcgtcgaag
     3001 tgtacgccgt cgtcgaagac ttggaaagcg gctatgggcg ggtacaggaa tttctggcgg
     3061 atacgcatct ctccctttcg tcggaacatc tgactccgca tctctactgg catgccggcg
     3121 atcgtgccat cagccatctc ttccgtgttg cgtccagcct cgattccatg atcgtcggtg
     3181 agtcccagat tctcggacaa atcaaggatg cattcgaagt ggcgctcacg cacaaggcct
     3241 cggggttgtt gctgaacaag atcgtcaaga aggccatttc ggtggccaaa cgcgtgcgta
     3301 ccgaaacgaa aattgctgag accgccgtct ccgtcagtta cgcggctgtc gaattggcca
     3361 aaaagatttt ctccaacctg accgaaaaaa ccgtgttgct gatcggggca ggggaaatgg
     3421 cgaagttagc ggctcgtcat ctgatcgcca acggggttcg tcaggtgcga atcaccaccc
     3481 gcaacttcca acatgggttg gagttggccc agaagtttaa tggcaccgca gttccgttcg
     3541 aggactacaa aacagaattg gccggggcgg atatcgtact cgtatcgacc ggcgcgtccc
     3601 attacctggt cacggccgac gatgtgcagc gggccatgcg acaacgaatg agtcgtccca
     3661 tgtttttgat cgatatctcg gtgccgcgca acattgatcc cgcggtgagg ccgattgacg
     3721 acgcgttcct cttcgacatc gacgatctcc atatgcgggt cgaacaaaac cgggaagacc
     3781 gtctgcgcga agcggcgaaa gccgagcaga tggtggtgga ggaagtggcg gtgctcgggc
     3841 aatggctgca atcgttggaa gtgacgccga ccatcgtcgc cttgcgtggc cggaccgaag
     3901 aaattaaacg gcgcgaagtg gataaagtcc ttgcgcggtt ggcgcatttg tctccggagg
     3961 atcgagccgc cgtggaagca ctcgcgtcag ccattgtgaa taaaatggtg catggcacga
     4021 tggtgacgtt gaaagccgag gccacgtctt ccagtggcgc ggcctatgtc gatgcggctc
     4081 gccggttttt tagccttgag gacgcacctg ctgcgtaccc cccggcgcag accgaggtgc
     4141 aggaggtatc cgaagacagc agcgatggga acggcgccaa ccgattttcc gaggcgtcat
     4201 tggtacagca tacaacgaag gagcaaagcc ggcgagtgag ttgacccgca tcgccgtgat
     4261 cccccatgag cagattattc gttaccgccg ctccaacctt gatgaccagc cgatccgatt
     4321 gtgagttccg atgagtcgcg cgcttattct cgggacacgt ggcagcaagt tagccgtgca
     4381 tcaaagcgag tgggttcagg cgcgtcttca ggaactggtc cccggtctca ccatctctct
     4441 caagcgcatc caaacctcgg gcgacaaaat ccttgatgtg ccgctggcca aaatcggcgg
     4501 caaggggttg ttcgtcaaag aaatcgaaga tgcgctcttg agcggcgaga tcgatctcgc
     4561 cgtccatagc atgaaggacg ttccgacggc attacctgac ggcttggaca ttctctgcgt
     4621 gcctccgcgt gaagatgcgc gggatgcgct gatcacgcga gatgggtgcc ggctcgatga
     4681 gttgaagccc ggtgcccgca tcggcaccag cagtctccgg cggcagtccc agttgctgca
     4741 ccatcgtcct gattttgtca ttgagatgtt gcgcggcaat ctggacacgc gtctcaggaa
     4801 attacgcgaa ggacagtttg atgccatcgt cttggctgct gcgggtttgc ggcggctggg
     4861 gtggaacgca gagattacag agtatcttcc ggtggagctc agcttgcccg ccattgccca
     4921 aggggcgctg ggcatcgagg cgcgcaggga cgacagcttc gtccgcgatg tgctcgctcg
     4981 atttgagcat cgtccgactc gaatcaccgt gacagccgaa cgggccttgt tgcaccggct
     5041 cgaaggtggc tgccaggttc cgatcgccgc gcacgcgctg ctcgatgggg agactttgaa
     5101 gctggacgcc cttgtcgcca gcgtggatgg aaagcgggtg atcaggcagc atatcaacgg
     5161 cctggccaca gaggcccatc agcttggaac cactcttgcg gaacggctct tgtcggctgg
     5221 cggagacgtg attctcaagg agatctacgg acgggcgtaa tggtcaagac gacgcgcaaa
     5281 ggaaccgtct atttggtggg cgccggtccc ggtgatccaa aactgctgac attgcgcggc
     5341 aaggagtgtc tggagcaggc tgatgtcgtc ttgtacgatt acctcgcgaa cgaagcgttg
     5401 ctgcagcacg tgccccgcac ggccgagcga ctgtacgtcg gtcggcgtgg tcgcggccac
     5461 tatcgtgatc aatcggagat caatcgcgta ttgatcgatc aggcccgtgc cggaaaatgt
     5521 gtggtccgtc tgaagggtgg cgatccgttt gtcttcgggc ggggtggcga agaggccgag
     5581 gctgtggccg cggctggttt ggattacgaa gtagtgccgg gtgtgaccgc agccgtggca
     5641 gccccagcct atgccgggat tcccgtcacg catcggaccc tcgcatcgac cgtgaccgtc
     5701 atcaccggcc atgaagaccc gacgaaagag cgcagcagca tcgaatggac tcgcttggcg
     5761 accgtccacg gtaccctggt ctttctcatg ggcatgacca atttgccgaa gatcgtgcag
     5821 tgcctgcggg ctgagggcaa ggatggctcg acgccggtgg ccgtgatccg gtgggggacg
     5881 cgtgtatcac agcggacggt tgtaggcacc ttggatgata ttgtggagaa agcggcggct
     5941 gcgcatatgg aaccgccgac cgtgatcgtg gtcggagagg ttgtgcgcct ccggccgcag
     6001 ttaaactggt ttgagcaacg tccgctattt ggaaaacgga ttctcgtcac gagaccgaag
     6061 ccgcaagccg ccgaattttc cgatctgatc caggctcagg gcggggaggc ggtggaatgc
     6121 cccactatcg aaattgcgcc ccccgaagac caggcgcctc tggatgcagc ccttgcgcga
     6181 ttgtctacct acaactggtt aatcttcacc agtgtgaacg gcgtagggcc attcatgacg
     6241 cgcctgctca gcacgcagcg tgatgtccgt gcattggccg gtctcaccat atgttgcatc
     6301 gggccgcgta ccgcggaggc gctggccgcc tatggtttgc gcgcggatgt gattccggaa
     6361 caatttcagg cggaaggcat tctggattcg ttggccgggc gacaccttcg cggcgccaag
     6421 gtgctgattc ctcgcgcgct ggtggctcgg gagctgctcc cggagcagtt gcgtgcacag
     6481 ggggcggagg tcgatgtggt gcccgtctat cgcaccattc ttccaaccgt cgcgctggat
     6541 cacctggttg gtcagctcgg agccggtgag attgatgtga tttcgtttac cagttcgtcg
     6601 acggtacgaa attttgtcgg attgtttccc tcgaaggatg aattgttgcg actcatcggg
     6661 gaaacgacga tcgcctgcat cggtcctatc acggcggcca ccgcccggga agccggcctg
     6721 acggtgcatg tgatggcggc ggagaacacc atccctgcgc tggcggaggc tatcgttcgg
     6781 catgttgagc atcagcgtga tcgccggccc gcctcggcga atcgatgatc gtggaaagtt
     6841 gatcggcaag atgtgcgtta cttaacaggg aggatgccgc atggttccag tgaaatcgtt
     6901 tatggttccg aaagacaagt tcatcactgt ggagcgcgat gtggatgtgc gcacggcggg
     6961 ccgcgtcatg cgggatcgca acatcggcag cttgttcgtc accaacggca aagacgtgat
     7021 cggcatcatt accgacacgg atatggttcg gcgggttgtg gcgaccgggg ccgatatgac
     7081 caaaacgacg gtggaacaga tcatgtcggc gccgctcgtg acgatcgaag agcataagac
     7141 gttgttggac gcgaacgact tgatggctca aacgcatctt cggcatctcg gggtgacgaa
     7201 ggacggccaa ctggtcggca tgatttcggt tcgcgatttg gtggtcttcc tgaccaattt
     7261 gccaaggaaa taagcgcatg gcctttccga tgcagcgcat gcgtcgaacg cgggaaaccg
     7321 agccgcttcg gcgaatggtt cgagagacga ccctgagccc gagtgacttc atctacccgg
     7381 tgtttgtcac cgaagggcag gggcggcgtg aaccgatcaa ttccatgccc ggacagtgcc
     7441 gtgtctccat tgatctcctg atcaaagagg cgctggaggt gaagtcgtta gggattcctg
     7501 ccgtgatcct ctttggcatt ccggatcgaa aggacgagcg agggagctcg ggattcgatc
     7561 cgaatggcat cgtgcaacgt gccattcgcg ccctcaaaga gcaggttcct gagttggtgg
     7621 tcattaccga cgtctgtatc gacgagtata cgagccacgg ccattgcggg atcgtgcgca
     7681 acgggaaaat cgtcaacgac gaaacgctgg attgtctgag ggctatggcg aagacgcatg
     7741 ccgaggcggg tgccgatatg gtcgccccgt cagacatgat ggatggacga gtggccgcca
     7801 ttcgtgatga gctggatcgg gccggattcg ttgacattcc aattatggct tacgccgcga
     7861 aattcgcctc ctgcttttat gcgccgtttc gcgatgccgc caactccagc ccgcagttcg
     7921 gtgaccggca gtcttatcaa atggatcccg ccaacaagcg ggaggcgtta cgggagattg
     7981 atctggatgt cgaagagggc gccgatatca ttatggtcaa gccagccatg ccttatctgg
     8041 acgtcatcag tgccgcgcgt gagcgaacgc tcctgcccat cgccgcctat caggtgagcg
     8101 gcgaatacag catgatcaag gccgccgcgc aggccggttg gctggatgag cgtcgagcca
     8161 tgatggagtc cctactgtcg atcaagcgag ccggcgccga gatcatcctg acctattttg
     8221 ccaaagaagc ggccgcgctg cttcagtcac ggcacgcatg aaaatttctc gcggtcttac
     8281 cccctccatc gccaggccct attcggtcgt gaccatcggc aatttcgatg gtcatcatca
     8341 tggccaccgg gcgcttttgg atcgggtggt gtcgacggcg cggcgcgagt ccggcacagc
     8401 gctggtgctc acgtttgatc cacatccggt caagatcctc gctcctcagg tcaatctgat
     8461 gttcctcacc acgccggaag aaaagctggc ccgcttcgaa gccgccggca tcgatgaagt
     8521 ggtgtttctg gaatttacga ccgcatttgc cgcattgagt cccgcgcagt tcgcgaagca
     8581 ggtcctgtgc gatggaattg gcacgcggga gttgttcgtc ggagaacatt ttgctttcgg
     8641 gaaggggcgg gcaggtcgca ttgcggatct gcttgaactc ggcgcacagc tggggtttcg
     8701 agtgcatccg acgccgcccg tgacgatcga cggcgaggtg gtgagctcga ccaagattcg
     8761 ccagatgatt caagcgggag atctgcagaa agccattcgt ttcctcggga gaccctacgg
     8821 cattgaaggg agagtaattc ccggcgctca tcgcgggacc gagctgggat ggcccacggc
     8881 caatcttcgc ctgcctgagg ggcgggtcat tccgccggat ggtgtgtatg ccgccagagt
     8941 cctgtggaac ggacgcgcct tggactcggt cgtctacatc ggcaccaggc ccacgtttgg
     9001 ggctggtgaa cggttactgg aggtgtcgat tctcgatgaa cggctggagc tctatgggga
     9061 aacgattcgt gttgagctgc tggggtttgt gcgtgaggat cgtgtattcg cctctgcaga
     9121 ggcgttgtcc agacagattg agttggacgt ggatgcagcc cgcatccagt tgcgcgaggc
     9181 ggcgttggat accgtctctc ccctccattc ccagtcatga gtgatggcag gtccttccac
     9241 agcgacgcct catccgcttc ataataaggt catccgagcc ctccgtacgc gcgcattact
     9301 tcaaccgggc caatcagtct tggtggccgt ttccggcggg ccggattccg tggccctgct
     9361 ctctctcctc cacgaactcg caccggcgtg gaatttttcg ctgacggtcg tccattgcaa
     9421 ctacgggctg cggggggccg aatcggacgg ggatgcctcc ttcgtcgctg agctctgccg
     9481 gaggctgaag attccctgtg tcgtcaaggc gctccaaatt cctgcgcgtg agccgggtcg
     9541 ttcgagctca ttgcaggcgc gtgcccgaga actacgctat cagttgttcc gtgacctggt
     9601 cactgagctg ggtatcgagc gtgtggcgct tgggcatacg gcggatgatc aggctgaaac
     9661 cgtcttactg cggatgctgc gcggggccgg tttgcgtggt ttgggcggca tgccgcatcg
     9721 ccgagggaat ctcttcgtgc gcccgcttct gactgtgacg cggcgtgaga tcctgtctta
     9781 tctggaaacg aaaagtttgt cttttcggac cgattccagc aatgcgacat ccgtctatct
     9841 tcgtaacaga gtccggcatg aactgctccc cgtgatgcag tcactggctc cggcgacggt
     9901 cccgttgctg gcgagacaag ccgacattgt gcgcgaagac gaccggctac tggaacgcct
     9961 ggctgcccgg cgtctggtcc gggcgaccgt caatcgagat tcacagacgc tcgcccttga
    10021 tcgggcggtc cttctgaaag aggagccggc cctgcagcga cgtatgctca ggcaggcgat
    10081 gcgcagtctc tcgccattgg ccatcggggt gcgtggagat gtggttctct cattgttagc
    10141 ctctttgtct gcggggcgct caggcggttc gtggacggtg ggatccctgg tggtgacatc
    10201 ggaacagggc ctggtgcgaa ttgcggtggg ggatcccgct ggtccgaaga cagaatcgag
    10261 ctctcaatct gcctcgggtg tcgctcttca gactgtcacg ctgtccagct tgccttgtga
    10321 ggtgccatgg ccgccaacgg gtgccttgat ccgcatctcg gtggtgacgc gtgagcgggg
    10381 gatggcgttg ctgaaaaagc cttcttcaac aatcgctatt tttgatgctg acaggctgtt
    10441 attgccggtg acggttcggt cttggcggca gggggattat tttttccccg ccgggatggc
    10501 cggtcgacga aagaaattgc aagattactt cacagatgca aaactgggtc ggtctatgcg
    10561 agaacacatc ccactgctgt tgtctcgaga acacatcgcc tggatcgtgg ggcaacggat
    10621 cgatgcccga ttcgcggcca ccgcttcgac gacccgattt atcgtcgctc gtgtgacgca
    10681 tcccgtgcgc cggaaaggag tcttgtagga atggaacgca tttttggtcg ccccattgtg
    10741 acgcaggagc agatgcgaac tcgaatccgt gagctcggcc gacagatcgc gtctgactat
    10801 gccggcaaag agttggtgct ggtaggggtg ctcaaaggag cgtatgcctt ttatgccgac
    10861 ctggcccgag ccatccgtat tccgatgcgg gtagaattta tcgtggtgac gagttatggc
    10921 gccggcaagc gaagctccgg taaggtcaag ttgatctccg acctgacgga accgatcgtg
    10981 ggcaaggatg tcctcttggt cgaggacatt gtcgattccg gtctcacggt gcagtaccta
    11041 atgaagactc tgtctcgacg gaaacctcgg tcgttgaaag tctgcacgct gctcagcaag
    11101 ccggagcggc ggcaagtcga ggtggatctg gaatatgtcg ggtttaaaat tcccaataag
    11161 tttgtggtgg ggtatggtct cgattaccgg caggagtacc gcaatcttcc gtacctggcg
    11221 gcgcttgatc aaggcgagga aggggagcag gagtccgcat gaaaggttgt tccccctgcg
    11281 gaacctatgg taacattctg caggcttagc taattttcgg tctgcctaat atcctcaaag
    11341 gagaggtgga tgaattcacg cgtaaagaat ttattgttct gggtcgtggt cggcctgttc
    11401 atgattttgt tgttcaattt gtttagcgtg ccgacccatg cgccggaaga tgaagtcata
    11461 ttcagcgatt tcatggccaa gctcgataag ggcgaagtca tgaaggtcac gatcaaagcc
    11521 aaccacatca gcgcgattct taaagaccaa agccggattc ggacctatac cgctgaatac
    11581 ccggaattgg tgaagcattt gcgcgaaaaa gatgtgcaga ttgaagcgcg gccgcctgat
    11641 gaaagcccgt ggtacatcac cttcctggtg acgtggggcc ccttcattct gttcctcgga
    11701 ctgtggttct tcctcatgcg ccagatgcag atcggtggca acaaggcctt gtcgttcggg
    11761 aaaagccgcg ctcgcatgtt gaccgaagag cgtaagaagg tgacgttctc agatgtggcc
    11821 ggcatcgagg aagccaagga agaagtactg gagattattg aattcctgaa agatccgcga
    11881 aagttccaga agctcggcgg gcgcatcccg aaaggcgtcc tgatcgttgg ccctccggga
    11941 accggaaaga ccctcctggc caaggccatt gccggcgaag cgggggtgcc cttcttcagc
    12001 atcagtggtt cagacttcgt tgaaatgttc gtcggggtcg gagcttcccg cgtacgggac
    12061 ctgttcgaac agggcaagaa gcacgcgcct tgtatcatct tcatcgacga aatcgatgcg
    12121 gtcggtcgtc tgcggggcgc gggccttggc ggaggacacg acgagcgtga gcaaaccctg
    12181 aaccaattgc tggtcgagat ggacgggttt gacacgacgg aaggcgtcat tctcatcgct
    12241 gccacgaacc gtcctgacgt gctggatccc gccttgttac gtcccggtcg tttcgaccgt
    12301 caggtggtgg tgaacagacc ggacctgcgt ggccgatcgg aaattctgaa ggttcatacc
    12361 aagaaagttc ctctgtcgac ggatgttgaa ctggaaaaaa tcgctcgggg tacgccaggg
    12421 ttctccgggg ccgacctcga aaatctagtc aacgaagcgg cgctgtgggc ggctcgtctg
    12481 aataagaagg aagtcgagct gatcgacttc gaaatggcga aggataaggt cctgatgggt
    12541 gcggaacgga agagcatggt gctcaccgat gaagaaaaac gcacaacagc ctatcatgaa
    12601 gcaggccatg cgctcatggc gaagctcttg ccgggaacgg atccggtgca taaggtcacg
    12661 attattcctc gcggccgtgc actcggcgtg accatgcagc ttccgactga tgatcgtcac
    12721 aattattcca aggatttcct gtacaacaat cttgccattc tcatgggcgg gcgggtggcg
    12781 gaagagttag tgttgcatga tgtgacgacc ggagcgggca acgatttgga gcgcgcgacg
    12841 gatctcgcca gaaaaatggt ctgcgaatgg ggcatgagtg aaaagctggg gccgctgacc
    12901 tttggacgga aggaagagga aattttcctc ggtcgagagc ttgggtccaa acgggatttc
    12961 agcgagcagg tcgccctgga gatcgaccat gaagtcaggc gcctcgtgac ggaaaactat
    13021 gaacgtgcga agcgaatcct gaccgacaat atgaccagtc tgaaggcact ggccgaggcg
    13081 ttgctggaaa aagaagtgct ggacgcattg gagatcgatc agatcctcat tcagggatcc
    13141 tcctcacaga cggttcctgc ctagtttgta aactgccggc ttcacagggg cacccatggg
    13201 tgttcctgtg aagcatgttc ctcatatgag ttccaggcca agggttggga catcctgctg
    13261 tcacctcatc ggtgcatgat ctcccatccc ttatctcgtc agcttacatc attccatcgt
    13321 gtgccgttct gagagcgcct taggacttct cttgaccctc gacactccat ctccattccg
    13381 tcctgtggtt attacggctg ggtcccataa catcaccatt caatcgaatc cactcgtcat
    13441 gggtgtgctc aatgtgacgc ctgactcatt ttccgatggg ggggcctact ccacagttga
    13501 acgggcggtc gatcatgcga ggcagatgca agctgacggg gccgatatca tcgacatcgg
    13561 cgccgaatcc tcccggccgg gagcggaccc agtcgaggaa ggtgaggagt tgcgccgctt
    13621 gatccccgtc gtggaagccg tgcgggaggc tgtatccctt cccatttcag tcgatacgac
    13681 gaaggcggct gtggctcgtt tggctattca ggcaggggcc cttatcgtaa atgatatcag
    13741 cgccttgcag ggagatccct tgatggctgg cctggtggct gagaccgggg tcgctgtggt
    13801 cttgatgcat atgcagggca cgccgcggac catgcaacgg tcgccacggt atgggaacgt
    13861 ggtggaagag gtcaccgtat ttttgcggca gcgggctcag gaggcgatcg cccgcggtat
    13921 ccgtccaact caaatcatcc ttgacccggg cttcggtttt ggtaagctcc aagagcataa
    13981 tcttcacatg ctcgcagagt tcgatgcgtt cacgaagttg gggtacccgg tgctggccgg
    14041 ggtatctcgt aaacagttta tcgggaatct gattcggcaa ccggttcacg aacgggaatt
    14101 tggtaacgcc ggggctgttg cggtagccgt tctgaaaggc gctcacatta ttcgtgtgca
    14161 tgacgttcga gcgatgaaag agacggccac ggtcgtgtca gccatttccc gtcacgcgcg
    14221 ttcttcttct gtagaggtat ccaatgcgta aattgttcgg cacagacggt gttcgcgggg
    14281 tcgcgaacct ggagcccatg accagcgaaa tcgccatgca actcggccgt gccgcggccc
    14341 atatttttat gcgccgggcg ggcaggcatc aggtcgtgat cggaaaagac acgcgcttgt
    14401 ccgggtacat gctggaatcg gccttgacct cgggcatctg ctcgatgggc gtcgacgtat
    14461 tactcgtggg acctctgccg acccccgcca ttgcgtttct tactcgaagt ttacgcgcgg
    14521 atgcgggcgt ggtgatttct gcctcgcata atccgtatca ggataacgga atcaagtttt
    14581 tctccaacga aggtttcaaa ctgcctgacg aggtggaagc gcggattgaa caattgatta
    14641 tttccgatga gatcaagcat ctgcggccga ctgccgatgc gatcggaaag gcgtaccgga
    14701 tcggtgatgc cgagggacga tatatcgaat tcgtgaaacg gtcacttccc cgcgacctcg
    14761 attttcaagg aattaagtta gtggtggatt gcgccaacgg cgcggcctac aaagtggccc
    14821 ccgcggtatt gcgggagttg ggtgccgaca ttgaagtcat cgccaatacg cctgacggga
    14881 tgaacatcaa cgaccattgc ggggcggtgc atcccgagcg actgcaggag gccgtgcgcc
    14941 ggaacggtgc gcacattggc atagcgctgg acggtgacgc agatcgagcg atcttcgtct
    15001 gcgagcaggg ccacattgtg gacggcgatc atgtcatggc cgcgttaggg ctcgatttgc
    15061 atggtcaagg ccggctcgct tctcagacgg tcgtgggaac cgtgatgagc aattttggat
    15121 tggaactggc catgaagaag gcgggcattc agttgatgcg aacgcccgtg ggtgaccggt
    15181 atctcatgga gcggatgttg gccgatggct ataatttcgg cggcgagcaa tccggccact
    15241 ttattttctt ggatcataac accacaggcg acggcttgat ttcggccttg cagatcctct
    15301 ccttgatgaa acgcacgggg aaaccgctgt ctgaactcgc gaaggccatg actgcggttc
    15361 cgcagatttt gctgaacgtc aaagtgaaac acaagccgga cttaaaccag attccggata
    15421 ttcagcaggc gattaagacg gcggaagcca cgttgaacgg gagtggccgt gtgttagtgc
    15481 ggtattccgg caccgaagcg ctgttgcgga tcatggtcga aggggaacgg gatgcgacca
    15541 ttcgtgaggt cgccgattac cttgcggaca ttgttcgcgc tcgtatcggg tagtaccggc
    15601 tccttgcccg aggcgtcgga tgctgccgtt cctgacgatc atctttatcc tcggaatcgc
    15661 tctcggctcg tacctccagt atttccccct cagcattggg ctgtttttct tcgcatcgac
    15721 tatcgccgct gtgcttgcag agcggcgagg actactcacc gcagggcaca gtagtctgag
    15781 gttggcctgc ctgttctgcg gctgtctgta ttggagcctg ttctcctggt cgacgtcgca
    15841 tgtcccggtg cccgaccgac ctgctgctct tccgtcaacc attgacggaa cgatcgttga
    15901 atcggttcgt catgcccctg ggcgattgac cgcgctcatg caggtcaccg ccaccgatga
    15961 tcccgacctc gccacgccgt tctctctccg tttgacctgg cgcgaccccg accgcgatct
    16021 tcaacgcggc cttcacattc gtctgcgaac ccgtgtgcat gcgccgtctg gaactttgaa
    16081 tccgagagga ttcgactacg ccgcctatct ggaagcgcag ggagtggatg ccgtgggatc
    16141 agtatcgggg gccggtgcca ttgaagtgct aggtgcagat gagggattgc tggcatatcc
    16201 catttcgtcg cgcatcgatg catggcgcag tcaggtacgg aatgcggcag acgcgctgcc
    16261 acagccggct cgaggtctgt tcctcagctt gaccatcggg gagcagggct tcctcgcgcc
    16321 ggaagtacgc gaatggttca tgacgaccgg gacggtgcac atcctttcca tctccggatc
    16381 gcatcttgga ctgatcgcac tgctgtcttt tgcgttggtg aggaaagcct gcctcctgct
    16441 tccttccatg ctgctcttgg gactttcacg atggttgatt cccagtaggc tggcagcatt
    16501 gctcactctg gtgccggtcc tgggctatac cctgttggcg ggtgcggaga cggccacgat
    16561 tcgttcggcc atcatgatca tagtggggct gtggacgata tggttgggca cgccgcagta
    16621 tcttcttcac gccttggcgg cggccgccgg cttgacgctg ctggtgcacc ctgccgcgct
    16681 ttatgatatt tcgtttcaac tatcctatgt gtccgtgtgg gtactggcgc tggcactgca
    16741 gcgacagcaa tccatcgacg aattacccct gccacagaaa agcctcgctg gtcgcacctt
    16801 ctactggtta caggaatcaa tccggctgac ggcctgggtg acattggcaa ccttgccatt
    16861 agtggcctgc tacttcaatc aagtgtcctg gatggggatc ttcgcaaatc tgctcatggt
    16921 gcccttcgtg ggattcattt tgttgccgat cagtctgctg tccgccgtct gggtcatcgt
    16981 ttcgcacagc agtacgttgc ccggtgccgg actcattgaa ctttttgctc aggctgtgac
    17041 ggttccgacg cagtggctgg ctggtctgcc gggagcggaa tggttcgtcg ccgcaccgac
    17101 ggttcccttg atggcgctgt tctacctgct aggctgggcc atgctgactg acaggccggc
    17161 tcatgcgccc ctgctggtga agcgcgccat ggcgttcggc atggcctgtc tcatcctctg
    17221 gtggctgtgg tctccgcgtc cgttcacgcg ggaggggcag gtgcggatca cgtttctcga
    17281 cgtagggcag ggagatagtg ccgtgatcga attgcccaag ggggaggtcg tgctcatcga
    17341 tggtggtgcc acgtatgagc gctttgacat gggacgcagc gtcgtcgcgc ccttcctctg
    17401 gaatcgcggt attcgcacca ttgaccatgt gatcgcgacg catcctcagt tggatcatgc
    17461 cggcggacta gcctggatct tggcacatgt tcaggtagag aacttctgga ccaatggtgt
    17521 cacgcgaagc gaggaattct ggcgcaagat cgagcggacg ttggcccgac ggcatctcca
    17581 ggcgcaggtc gctgagcagg ggagacgact ggtggacgac gcagaatgtg atattgccgt
    17641 gttgaatcca ccgccgggcc ggaacgcatc ctctgcggga aaacagcaat cgttgaataa
    17701 tctgtcggtc gtgactgagc tcacctgtgg cggtcgacga atgttgttca caggggacat
    17761 cgagcgggaa gggttggccc gtatggtgca atccgggcat cttcgtcata tcgatttgct
    17821 caaagttcca caccacggag cgctgagctc attggatcgt gaatggttga gcagtgttca
    17881 gccagatatc gccgtggtat ctgcggggcg ccgcaaccca tatgggcatc cagcgggtga
    17941 ggtcatcgca gcctacgagt cccttgagac gcagctgtgg cgaacggatc aggacggcgc
    18001 cgtgtgggct gatcttgacc tgaacaagca gtctctgacc atgcacagca ccagagaatg
    18061 gcagcttcaa ccagcgttaa tcccgatccc tcagtgggcg attgagcagg ataattttca
    18121 tcgcctgtgg cgccggtgga actggaacta ggcacggtcc cggtctgagc atcgtgattc
    18181 ttatcgctcc cgccgggcag aaatccccag ttgcatggct cccgaatgtg ccgggtgccc
    18241 cgtttttcac caatgcggct gtcaattttg ccggtgtggg gaaaacatgt cggcataagt
    18301 tggcaatatt gcgaatggaa ccgggagtgt catcaaggca tagcacatgc agagatgttc
    18361 aacgcctggt cacggcagat cttccgctga cggtggggca tagctgaccc cctgcggacg
    18421 ataccgcagc ccccaggata aagagcgaga gaaggttagg cgatgatggc caatcgactg
    18481 ttgtttctag ccccggttcc accctccgat caccagggcg gtggtccttt gcggatgttg
    18541 cacctgctac gttttctggg gagccgcttt cacgtggacc tggtcgctcc ggcggttgat
    18601 ggctgggaga atgcacagaa ctcattgcag ggcgtgtgcg cggagacgac gtttgttccg
    18661 cctcaaggtc ccggattact ggatcggctc ggacgggtca gcccctacgt gaaagatcgc
    18721 gccttggctt ctgtcgtgcg cgagcggttg gcnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18841 nnnnnnnnnn nntcagcccc tacgtgaaag atcgcgcctt ggcttctgtc gtgcgcgagc
    18901 ggttggccag tggagtctat ggcgcagtcc acgtcgaaaa gcttggactg attgcatcgt
    18961 tgccgacgca attggcaatc ccggtggtgt tggatatttg gtcatacggt ctgccaagcc
    19021 cgctagggat attcaagagc ggcggtggaa cgaccggtcg gccgaagcca tttgtgcgtc
    19081 ggctcaaatt ggggttgtac gaccgatggt gctggccgtt gacctcttgt gtcacggttg
    19141 tttcggagga agaccggata cgttgtgagg gcgcacaccc aggccagcgt gtcatcgtcg
    19201 tgcccaacgg tgtcgattgt caggcgattc gtccgaaatc cgatcatgcc ctgacgtcac
    19261 ccgtgttgct cttctcaggc gacatgggcg ctgagccgaa tgtggaggcc gctacggtcc
    19321 tcgccacgga agtctttcct gcgattcgcc gggaatttcc caaggcggaa ctccggctgg
    19381 tggggagaaa cccggatccg cgggtagctc gattggccgg tccagggatc atggtcaccg
    19441 gggcagttcc cgacatgcag gtccatctca gggccgcgac catctatgtt gcgccgcatt
    19501 tcaccggccc cgcgacgcgc acgaaattgt tggaagccat ggcagcggga ttgccgatca
    19561 tcaccacttc actcgggact gaagggatga aagtgcagcc gggccgtgat ctgctcgtgg
    19621 ccgatcaacc ggccgatatg atcgaatcca tccagacgtt gctcgcgagt cagcccgatc
    19681 gtgaacgttt tgcccaggct gcccgccaca tggcagaggt ctggtatgac tggagccgct
    19741 gtctctggcc gctggagccg ctctatcaaa atctgctcgc cccgaagccc gccgtagcct
    19801 gttgagggtg tggtcgcaac cagctatgcc tgccacgtca tcgcgctcag tgcaaccccc
    19861 gcttcaggaa tctgttgtgt tctgcctacc gtccacgtag aattttgtgc ccgtgcacgt
    19921 cgtaggccct atgacgattg agcaaagcct cccactgaca ccatgacgtt gatcccgcac
    19981 tccaagccct cgctgggaca agaagaacta cgagcagtga ccgaggtgct tcggtcgggc
    20041 cagatcactg ccgggcccat ggtcgcgcaa tttgaacgag ggatcgccgc ctacatcggc
    20101 ctgcatggcg gcgtggctgt cagttccggc accgtggcgt tggaattggc tttgcgcgcg
    20161 ctcggcgtcg gccatggcga caatgtcatc ctccccagtt atgtgtgctc ggcaccctgg
    20221 ctggctgtgc aacgggtcgg cgcccaagcc agactcgtcg atatcaatcc gactacctat
    20281 aatctcgatc ctcagaaagt gcgcaaagcc cgcaccagcc gtacgcgcgc ggtaatcgtt
    20341 ccccatatgt tcggcctgcc ggcggatttg accagtctgc agtcattgga catcccgttg
    20401 atcgaagatt gcgcacaaac actcggtgcc atggagcagg gacgcgcggt cggcagcgtt
    20461 ggaaccctga cggtttgttc gttttatgcg acgaagttgc tctgtaccgg tgaaggcggg
    20521 atggtcttgt cgaacgatga agctttgctc gagcgagttc gcgcgctccg cgaatatgat
    20581 aaggcgccat ccctgaattc ggcggcgggc aattgcaaat tgacggatct gcaagcggcg
    20641 atcggcgtcg cgcaactgaa tcagttggga gagtttctcg acaagcggtc ggccttggcc
    20701 gccttgtatc gtgacatgct gtcgccggag ttgttcacaa tgcctgtcgt gcctgccggt
    20761 cggacgcacg tctatttccg gttcgtggtc cgactgatga aaggattaca gtctgccgac
    20821 gactttacgg actatctttc ccgcctggcc caccgcggat tgcaatgccg caagccggtg
    20881 tttcgtcccc tgcatcgcta tctcgacttg ccggactttc ccgccagcga tgaggccgat
    20941 gcgtcggcca tttcgctgcc gattcatccc tcactgacgg aagaagcgat ccggcaggct
    21001 gcgcacatcc tgcaggaaga gctgcactga cgcaggcgtc ccgccgaatc gttctccctt
    21061 gacccttgcc tgagtgatcg gcatgatgtg agcgaatgtt caacgtgatg tgacggcgtc
    21121 acattcttcc ccagctgaac ccggagacaa tcggcatggt gcccacggtc gagtggaaag
    21181 agggagcggt tcgccttttg gatcagagcc ggcttccatc gcaggtcgaa tttcttgact
    21241 gccgcgacta tcgctcagtc gcgcaggcca ttcgagagtt gaaagtccgc ggcgctccgg
    21301 cgatcggtgt gacggctgcg atgggcgtgg ccctcggtgc gcagagtgtg gacgccgacg
    21361 agtattcctc gttcgtcaaa caggtcgacg cgatttgtga tcacctggcg gcctcgcgcc
    21421 cgacggcggt gaatttgttc tgggccatcg cccgcatgaa acaaaagctg gcatcactca
    21481 agggtatgcc gatcgcagag atcaagcgtg agctgatccg tgaatcgcaa agcattctcg
    21541 acgaggacat cgcgctctgc aaggccatgg gccgtcatgg cgcgaccgtg attcaaaacg
    21601 gccagacgat cctgacccac tgcaatgccg gcgcattggc gacggcgggg tacggcaccg
    21661 cgctgggtgt catcagggct gcgtgggaac agggaaaaca gattcgtgtg attgccgacg
    21721 aaacccgacc ggtcttgcag ggcgcgcgct tgacggcctg ggaactcatg caggacaaga
    21781 ttccggtgac gctgatcacg gacaatatgg ccggcagcct catgcggcag gggaatattc
    21841 aggtgtgtgt cgtcggcgcg gatcggattg cggccaatgg tgatgtcgcc aacaagatcg
    21901 gtacctactc ggtcgcagtg ctggcccggg cgcatgggat tcctttttat gtggccgcac
    21961 cgtacagcac gattgatctc gccaccaaga ccggcgccga gattcccatc gaagaacgaa
    22021 accccctcga agtgacgtct atccacggca gccatcctgt cgcgccgtcc ggtgtcgctg
    22081 tctataatcc cgcgtttgac gtgactccgg ccgaattgat caccggcatc atcacagaac
    22141 ggggcatttt caagccgggg gaactcgccg gtgcattcgg gacgtcacgc cctccgatca
    22201 agtccggcaa cgtttcctga tactggcttc tcgggtaggt gtggcacatt attactcatc
    22261 ctcgagtgcc gaagaatctc agagcccttt atcttgccag cacttccgtc gcttctttat
    22321 aatgccgcga gagtaggccg ttgcgatatt tttagctgaa ggagctgacg atccatgagt
    22381 gaacgaaccc ttgccatcat caagccggac gccgtgaaaa aggatgccat cggcgacatt
    22441 attaatcgat atgaaaaggc ggggttgaag ccggtcgcta tgcgtctgat gcacctgtcc
    22501 aaagccacgg cgcaagggtt ttatgccgtt cacaaggcac gcccgttctt tgatagcctc
    22561 tgtacgttca tgtcctcggg gccctgtgtg gtgctggttc ttcaaggcga caacgcggtg
    22621 aaaaagaacc gcgaactgat gggggcgact gatcccgcaa aggcggagaa cgggacgatc
    22681 cgggcggccc atggcgcgaa catcgaattc aatgcggtgc acgggtccga tgcgccggag
    22741 acggcgaagt ttgaaatcgg gtatttcttt cctgaaatgg agttggtcgg gtaggcgcac
    22801 attgagcgca agcgtttccc acgtcatgca gactcgacgg ccgttttccg gccgtcgagc
    22861 atcccttccc ctggtgatcc tgctgatggc gatcggcagc ggttgcgccg ggccgcccgc
    22921 agttgttccg gttgctcaac ccatcgaaaa tccggtggtc gaggccgaga ccaggctctg
    22981 gtaccaagct tcgagtgcct tttctgacgg ccgctattcc gcggcgacgc atctctacga
    23041 acggtatctg accacctatc cgaagtcgcg gcgcgcgaat gaagcccact gggaactggc
    23101 gcagtcgtat gaacagatgg gggaggcggc gggcgcgctg aaagagtatc ggatattggc
    23161 agggccggag ggtgctccgc tttcgacgca gagcgcctat gctgagcgag ccctgcatcg
    23221 tatcgaagcc ttgcggaatc agtcgagcct gcccggcgcc aggtctggtc ataccgcact
    23281 ctacgtatcg ttcagcaatt tgcctccgat ggctcaagtg gaaacctgga ttcagcggct
    23341 gagcgcacag ggcgtcagcg ccattcttat ggatgccagt ttggagtcgt cgtttaccag
    23401 gccgcctgca ccgaccggtc ctcctcccag cagccccttg ccgaagttgc ccgcaggcgc
    23461 gttgttttcg acctcgcagg ggcctgtcat gacggattgg ttcagtgtga tggtgccgca
    23521 ggcgcatgaa ctaggcatct cggtctttgc cgtgattgac ctttttcacg cgccgctctc
    23581 cgatcaccgg caggaatccc ggacgctgct gtatgacccg acgcggcgaa aggtgcactc
    23641 ctggacgcag ttcgatcttc tcgctccgcc ggttcagcag gaagtggcgc agttgttggc
    23701 cgacttgctg aggagcgggg ttgacggcat ggtcattcgc gcgcgcgcgg agaacagctt
    23761 tgcctatgag gtcagtgacg gcgtgttgcg ccagtttgag gcgcaggtac gtcagccggc
    23821 gtcggaagtg gcgcaggcgc tccgtgagcg gatgtccgtg cggcaggacg cgggggcgct
    23881 cgcctccgac aagacgcttt ggcggtgggt cggctggaaa tcacggcagg agctcgatgt
    23941 gctggcgcgc ctgaagaaat atttgcagaa ggccgtgccg cggttacgca tggtgctgga
    24001 gattcatcct gaagccttgt cgaatccgac gtccgccctg gtgaactatg gagaggacgc
    24061 cgccgaggcc cgccgccgag gttttgattt gttattgggc ggcccgtccc gtgaggcatc
    24121 ggatgtacgc acgttcggcg ggtcgttcaa gggttggagt cgcgatgtaa ttcaatccga
    24181 gaaaggcgag ccgcaaactc ttccacaagg ctgggtcttg ctgcgaacgc caaccgagca
    24241 tggtggtggc atgtttatgg gattggccca gcaggcggac gaattgcgga cgccggacat
    24301 ccgtcatctg gtgtttgtgc cggatgcgcc gccagcgatt ccttgacaaa gattccggca
    24361 gcttttacga tccggcggca caaaaatatt gaaggggctt cttatcaacg aggtcgcgcc
    24421 gagcatttcc agtggactga gactgctact gggaggggtg tcagcgaccg atgcaagggg
    24481 agagtcatga taccgtccaa tctccgttac catcaggaac acgaatgggt ccgcgccgaa
    24541 ggtcaacagg cgacggtcgg gatcagccat tttgcacagg atgcgttggg agatatcgtg
    24601 ttcatcgatc ttccaaaggt cggtgccaag gtgactgccg gtcagcagat cggcgaggtg
    24661 gagtcgacca agaccacgtc caccatttac acgcccgtca gcggcaccat tgcgaagatc
    24721 aacacggagc tcaaagacca tcccgaggcc gtcaatgccg atccgtatgg caaggggtgg
    24781 atggctgtca ttgatctcac gactccgggt gaagtggaca agctcatgac ggctgctcag
    24841 tacgaagagt ttttgagcaa gcagaagcac taactccgaa catccttgca ccattgaata
    24901 ggcgacgcat cctcgtatgc agcctgtgat tcaatcggca ccggtttact gagtcattct
    24961 tatgtcgaag catctcgcaa ttcttggcgc cggtcccgga gggtatgtgg cggcgattcg
    25021 cgccgcgcag ctcggggcgc gtgtgaccgt ggtcgaaaac caggcgctcg gcggcgtgtg
    25081 cctcaactgg ggctgcattc cgagcaaggc cctgttgtcg gtcgtggagc tgggtgacaa
    25141 ggccaaaaag gcgaaggact tcggccttct cctcaacggt ccggtcgcct atgaccctgc
    25201 catcatggtg gcgaggaaga acaaagtcgt ctccacgctg gtcaagggca ttgccacgtt
    25261 gtttaagacc tggaacatcg aacatgtgga gggcacgggt gagttggtgg atgcccgaac
    25321 cattcgggtg accaaaccgg atgggactac cttgcaagtg gccgccgatg gaatcatcgt
    25381 cgccaccggc tcctcatggc cgaacctgcc gctctttccc atcgacggaa ctcagatcat
    25441 taccagcaag caggccctgg acctaacccg aatccctgcc agcctcctca tcgtcggcgg
    25501 tggcgtggag ggctgcgagt ttgcctctct gtatagcggg ctgggagccc aggtgacgct
    25561 ggtcgaattg gtcccgcgaa tcctgccgct ggaggatgaa gagatcagcc agatgatgga
    25621 gcgggagttg aagaagcggg gagtggacat tcggaccggc gttaccgtcg atcagatcgt
    25681 ccggcagtcc gacgtggtga cggcccatct tcgtgatggc ctctcattga acgtggagca
    25741 ggtgctggtg tcggtagggc gaggattcaa ttcgcgcgga atcgggctgg agaaagcggg
    25801 agtgcaggtc ggctctcgcg gtgaaattgt cgtcaatgaa cgcatggaaa cgaatgtccc
    25861 cggggtctat gcgatcggcg atgttgtggg taaggcgatg ttagcccatg tcgcctcgca
    25921 gcaaggcaag gtggcggtcg agaatttcat gggtcacgcg cgcgcaatcg attatgacgt
    25981 catcccgacg ggcatcttta cgttacctga aatcggacga gtgggattga cggagcagca
    26041 ggcccgtgat cgttgtgtgg gcgccggcaa ggatccccaa cagtccgtaa aggtaggacg
    26101 tttccgctac ggcggattgg ggaaggccca ggcgacgggg gatattcaag gattggtaaa
    26161 ggtagtggtg gatacggaga gtgaccggat tctcggtgtc cacattctcg gcgcccatgc
    26221 aaccgatctg attcacgaag ccgcgctggc gatgcatctt ggcgcgaccg tcgcgcgtgc
    26281 ggcagagatg attcatgcgc acccgaccct ggccgaggga ctcatggaag ccatggaaga
    26341 tgtgcatggg cacgcgatcc atctcgcgcg aaaaccggca acgacatgat gcaatcattg
    26401 ctaatcaaag ttgccatgct cgccgtgacg ctgggttcat tggtgtggat tgcctcggtc
    26461 actcccgtga cgaaggtgat gccgggacaa cctcaactgc tcccgaaaca ttccgtgaca
    26521 acagtgtcat ctccgccacc agtggaggtg cctgcgacga ggccggccct ggcaagcgtc
    26581 agtcaggcgg gaacgccatc gcgtcgacag gtggcgatgc cgattgaaga gtccgaatct
    26641 gcatctgcgc gtgtatccga gaaagcgtca acagactcgc cttctgctcg acaggctggt
    26701 gctcgacagg tcgacctgaa ccaagccacc ctctcagagt tggaggcgtt gcccggcatc
    26761 ggaccgaagt tagcgcaacg agtcattgag catcgcgatg agaatggccc cttccgttct
    26821 gtagacgact tgcgccaggt gaaaggcatc ggccggaaga agttcgaccg cctccgtcca
    26881 cacgtcctcg tcaccaacac taaatcgtta gcacgacaca aaggaaccct gtgacaccgt
    26941 tagcgcagca gttggatctc atacttcgag ggatcgttga ggttattcag cagagcgagc
    27001 tggaatcaaa gctggctcgc tcgatcaagg aaaaccgtcc ccttcgcgtc aaggccgggt
    27061 tcgacccaac tgcacctgat cttcacctgg gccataccgt gttgattcat aagctcaagc
    27121 atttccagga cctcgggcat caggtgatct tcctcatcgg cgattttacc ggcatgatcg
    27181 gtgatccgac cgggcgatcc gaaacccgcg tcgcactgtc gaaggaaaag gtgctggaga
    27241 atgccaagac gtatgagcgt cagatcttca aaatcctcga tcccgcaaag acgcaggtgg
    27301 agttcaacag ccgttggatg agcacgatga ccgccgacgg gttgatcgaa ctcagtgctc
    27361 attacacagt cgcgcgcatg ttggaacggg aagactttca caagcggtat acggaaggca
    27421 cgccgatcag catccatgag ttcatgtatc ccttgatcca aggctacgat tcggtggcgc
    27481 tgaaagcaga tatcgaatta ggcggaacgg atcaaaaatt caatctgttg atgggccggg
    27541 atctccagcg ggactacggg caggaggcgc aggcggtcat caccatgccg ttgcttgagg
    27601 ggactgacgg cgtacgcaaa atgagtaaaa gcttcgggaa ctatattgcg ctggaagatc
    27661 agccggctga tatgttcggc aagcttatgt cgatcagcga tacgctcatg catcgatact
    27721 atgagctact gaccactgag aatttggctg gggtaaaggc ggcgcatcct atggatgcga
    27781 agcaggggtt ggccgagcag atcgttgccc ggtatcacgg cgctgacgcc ggccgtgaag
    27841 ccaggaccgc gtttcagcag aaatttcagg cgcgggagtt tccggaacag ccggacgcgc
    27901 atgtcgtcct cacgccgtcc gatgtgaaag atgcgagcgc accctccatc gggctggtcg
    27961 atctgatcgc gaagaccgga ctggttccca gcaagagcga agctcggcgg ttgatcgtgc
    28021 agggtggggt ggaaattaat gagcagaaga tgaccgatgc gaatggcgcg gtcccattgc
    28081 tcgtcggtca gttgcttcgt ttgcgtgtcg gtcgcagaaa attcgccgtg gccgagtaca
    28141 aggattgagc aagtggcttt caggttcctt gacttagcgt cgttgccagc gtaggattcg
    28201 acttctcttc aatcaggggc gggcgtagct cagtggtaga gtccttgctt cccaagcagt
    28261 tcttgtcatc cccttaatcg ggcggctgat ctggtcaaat ccgatctgga agcggcttct
    28321 cctcgtttct tcctgtcaaa tttcttaagt ggtattaagc tgtcgtcagg tgagttttgt
    28381 tgtttggctg acactgtaat gacaccaatc tcattggtag tcgacggcga aacagccaca
    28441 gcttgttcct caatgacgct gtttggcctg ctgccagtcg agaggactga aggccgggtg
    28501 agatcgggcg attggggagg aaagcctagc cgattttctc tggattccag agagccaaca
    28561 aacataggat tgagcgagtg acactcgctc tgatcttgtg cggcttttct gccagagtca
    28621 tttgtcattt cagggccacc gctacaaact gtttcgggtc gagcgaatcg tggctcttgg
    28681 ccaaactcgc tatacggctt gtttggcgaa gatcgtaccc atgatcccgt ctgtgacttt
    28741 agctttcgag agggaaggat actgcaggag cagacggctt acggttgctg tgcgagtggt
    28801 ggtttgtgtc ttcctcataa gccttttcac atggtccttc accgtgtatt cactcaagtg
    28861 taggtgattg gcaatttcct tgttcgtcaa ccccgccgcg aggtagcggg ctacagctcc
    28921 ttcgcgatgc gttaatcgta tttgctctcg tgaggaaaag gagtctgctt ctccttgctc
    28981 aatgattggt tcgataagca gaagcaagcg accacactca tgggggagct catctggaac
    29041 tccaaaccct cgtagtaata caccaccttg cggtgaagag accatttgct gcacccgcac
    29101 cgcttgccag tccatacctc cgccgcttct cgttagtgca accatcagtt catgacacag
    29161 acttgacaac tgaggaggaa ttaggactcc cgactgtggt tctggctgcg aagggaaatg
    29221 taaggacagt aggcgatgcg cctcgcgact cagatagatc agctcgcctc gtagcctaaa
    29281 gagtatgatc ccggagatca tattgctcat tctcaaactc cattgtgtct caggaaagct
    29341 atcttcgact tgcggacact tgaggagtct aaggtggtta ggggagggcg acaatcccac
    29401 atgaggtgcc cctacctcta gggtaggaag acaaatctgc gtgcacctaa atacgtgtaa
    29461 ataggagaga atgctcctgg caatcaagac tcaactgttc tggatgtgag ctgtccgagg
    29521 ccacgccata caaacggtga ttgtatcccc tgagcgtttc ttagctccga tggctggcgc
    29581 agagttctcg gcaattcaga ttgtgaggac ctaccgtgta actactgtta tccaataggc
    29641 gtacccccat ctggggtgat tgtggggacc aggtggcaac ccgtatgctc cgccgcgtgc
    29701 gtgagtaaca acagaaatcc accaccgcgt cacaaggagc ttcagcgatg cgttccacct
    29761 atcagccgat tcgtcgactc ctggttgcct tggctgccct cctcttgctt gatcccggac
    29821 acggcctcga tgctaaggag acggatacgg agaccccaat tggtgcagtg ggtgggagta
    29881 ttcatggcga cccgtttaca ggcactgcaa ccgcgagtat tcccatagag atcccgccgg
    29941 gacgaaatgg cgttcaacct ggcttgcaac tcgtgtatag ccacagcaat gggaacggtt
    30001 ggattgggat gggatggaag ctggagctag gttcgatcga gcggcagagc cgttttggag
    30061 tagactacgc gaagaacgat tacacaattc agatgagcgg tatgtcgacc gagttagtac
    30121 aagctccgct tccagcctcc agcgatgagt atcgagcgaa gtttgagggt agcttttcca
    30181 aaatcaagat gctctcgaac ggaggcttcg aggtcaccga caaaaaaggg acaaagtacc
    30241 tattcggcca atctggtgtt tctcgcgtgt ctcaccccac cgattcatca aaaatctata
    30301 agtggcttct cgatcgtgtg gaggatcggg acggcaattt catgactgca acgtacagcg
    30361 ctgatcaggg gcaggaatat ctgtcccaaa taacctatac gggaaatgga gcagcccagc
    30421 caggtaatac catcaagttc tatttggaga gcagaccgga cggtcaaact ctctatactg
    30481 cgaatttcca agttattaca gcacaacgcc tcaagacgat tgaggtattg tcaggcacaa
    30541 ccagactccg ggcctacaaa ctcgcgtact caacgagcgc cagtacaggc cggtctgtac
    30601 tgacttcagt tcaacagttc ggcaaagacg cggtgctgga cggttctttt actgtgaccg
    30661 ggggaacatc cctcccacca gtgtcaatga cttatgagaa cgaaagtatg tcgcttggat
    30721 ccgatcagct gtggggctcg aagtcctatg gcatcggctg tgccgctgca tcgaattgcc
    30781 gccccaattt tgcctatgtc gatatgaacg cggatgggcg tacggatttc atctatcaac
    30841 gctccgatat cgacgaaatg cacgtgttgc tttctactgg ttccggattc ggaagcgata
    30901 cgaactgggg aatgaagtct tttggtattg cgtgtgctgg agcatcgagt tgtcagcctg
    30961 cgttttcgta tgccgacatg aatggcgacg gaaagactga ttttgtttat atgcgatctg
    31021 acctagacca gttccgagtt atgctttcga ctggaactgc atttagcacc gataccgtat
    31081 ggggctccaa atcctttgga attgcgtgcg cgggagcttc gaattgtagg cccaatttcg
    31141 cttttaccga tgtgaatggt gacggcaagg ccgattttgt ctatcagcga tccgacattg
    31201 atgagctgcg agtactcctt tcaacgggaa ttggatttag tgccgatacg aattggggaa
    31261 tgaagagtta tgggattgcc tgtgctggcg cgtcgaattg ccagccgaat tttgccttca
    31321 ccgacctgaa cggtgacggc aaggccgatt tcgtttatca gcgctcggat atcgacgagc
    31381 tgcgagtcat gctgtcgacg gggacggctt tcgggcctga tacaagttgg ggtgtgaagg
    31441 cctacggtat tgcctgcgcg ggggcgtcca attgtattcc caatttcaca tttgcggata
    31501 tcaatggcga cggcaaggct gattttgtct atcagcgatc cgatatagat gaacttcggg
    31561 tgatgttatc cactgggacc ggcttcgcga ctgatactgc atgggggatg aaagcttacg
    31621 gcatcgcatg cgctggcgcc tcaaactgcc gacctgcctt tgggtatttc gatgtgaatg
    31681 gggatggaaa agcggacttt gtgtatcagc gctccgacat tgatgagctt cggattctcc
    31741 tgtccacggg cagtgctttt aggccggatg cagtatgggg aatgaaaggc ttcgggatcg
    31801 cctgtgcggg cgcaatgaac tgtcagccga gctttagtta tgttgataca aatggtgacg
    31861 gaaaagggga gtttgcgtat catcgcgatg caacagacca gattcgtgta ttgccaagtt
    31921 ctcccgatgg aatcctgtta gccaccatga ccaatggtac gggtggggct gctatcacaa
    31981 catacgcacc atcaactcaa ttcagtaaca ccctcctacc atacactacg cggctgctta
    32041 cctccactgt cacgtgcgac aactggggcg ggagtagctg tgtgggactg tcctcgacga
    32101 cgacctatac gtatagcggc ggctatcacc atctcgcgga acgtgatttc cgtgggttca
    32161 actacgccaa ggtgacgggg ccggtaggac cgaccggcga acaactgatc accgagacgt
    32221 ggttccatca gggcaacgac gtggcggttg ataccaacaa ccccaacgtc gcgaacgggt
    32281 acacgaaggg catgccctat cgtagcaagg tcaccgatgc gaccggtaag gtctatagcg
    32341 agactactac tacctatatc gccgacgtgg atggcgccgc ccctttcttt actcccgtgg
    32401 cgcaagtaga cgcatcgatc gagaatggtg ccaagcaaac ccggagcgtc ttcgcccaat
    32461 acgacgccta cggcaacgtg ttgcgcgagg accagtatgg ggatctggcc acgactgccg
    32521 atgatcggac cgtggtgcgg acttttgcca acaacacgac cgactggttg cttgggtttc
    32581 cgacgagtga gactagctat gcgggcatcg gcacgaccac gcaagtggcg caaaccaatc
    32641 tttattacga cggcacgacg agctgtgcca ccgcgtcggt gaatcaagtg ccgaccaagg
    32701 ggcatgtgac ccggacggta cgctggctta acggcggcac cagtcccgaa accaggatgg
    32761 cctacgatgc cttcggcaac ctcacctgta cccgtgacgc cttgggtcaa accagcacgg
    32821 tgaactacga tagcacgaac accttcgtca agacggccac caatccactc ggtcatgtgg
    32881 tcacgacgca atattacggc gtggatggtg tattgttgga caagggcctg tacggccagg
    32941 tcaagagctt gaccgattcg aatagtcaaa cgacgaccag cgaatatgac gctctcggtc
    33001 gcaagagtaa gacgaccaca ccggacggcc taactacgac cgtcatctat aactatgggc
    33061 cgggtttcac ggtggggacc cagcacgtgc tctcgagtac gagtggtgcc ggcctcgcga
    33121 ccgcgctgac gagcgccagc tattttgatg ggctgggccg aggcgtcaag aaggagacgc
    33181 ctggtccgga cagcaagacg attgtcacgg aagtgcagta tgacagtcgg ggcgccgtgc
    33241 ggaagaagag cctgccctat ttcaaaacgt tagaatctgt gacgggccgc tgggcgacga
    33301 cgagctatga cgcccttggg cgagttgtgc gtatggacag cccggatggc acccgtggcc
    33361 tggcctgttt taccgactgg gtcaccgtca cgatcgatgc cgccgatcat cgcaagcgcg
    33421 agacgaaaga cgcgtatggc cggaccatcc gggtggatga atatcagggc accgcgagta
    33481 cctgtgacac cacggtcggc acgccctacg ccaccacgac ctaccagtac gatgtgcagg
    33541 gcaatctgct ctccgtgacg gatgctcggg gcaacgtctc caccatgacc tacgacacgt
    33601 tgaaccgtaa gacggccatg catgatcccg acatgggcaa ctggagctac gtctacgatg
    33661 ccaatggtaa tctgacgaaa cagaccgatg ccaaggccca gatcctctgg ttccgctacg
    33721 atgccctcaa tcgccgggtg cagaaggatt tcaccacaca aaaggcgctg ggcgccggag
    33781 atgttcgcta cacttatgac gggacgacga ataaccggaa gggccgactg caacaggtgg
    33841 tcgatgcctc tggcaccgtg gtctttcagt acgatggcct cggacgcatc agccagaccg
    33901 acaagacctt ggacggcacc acctacacca cccagagtac ctatgatggc ttggggcggc
    33961 tcctgaccgt cacctatccg agcacacctt cgaagaccat cagctacgcc tataacgggc
    34021 cagtcctgga caaggtattc gaaggcacca caacctatat tcagtacaca aaccacaatg
    34081 cgctgggcca ggccggtacg accacctacg gcaatggagt ctcgacgacg acgacctatg
    34141 ccaatgccaa caataccatc tgtagccagc agaacttccg cctgtgcacc cttgtcacca
    34201 atggcccagg gagtggcggt ggcgggggtg gtacgagcac aacatacagt gccctcgctg
    34261 atttttctgg cacgcagggc tcgcgtggct ggtattactt gagttcgacg ggaacccagc
    34321 ttacgtggaa cggctcttat tggactggga cggatggcta ccttggcctc tggaacgatg
    34381 gcggtcatcc cggcaacagc acggatgcgg tgcggcgttg ggtcgccccg tcagcgggca
    34441 gcattcaaat caccggcaat acctttgatg gtgacacctc ttgcgggact gatggggtgg
    34501 tggtcacgat taagaagaac ggggctgtcc tttggaccca aactatcgcg gcgggcaaca
    34561 cgacggggtt cacctttaac ctttcaaata gcgtggtcgt tggcgatcag atcgactttg
    34621 tgatcaataa actcaccact tcgtcttgcg acaataccgt tttcactccg accatcgtgt
    34681 tgacgactgc cgggggcgga agcgggccgt tgctcaatgg gacgtataca gccccggcct
    34741 cgaccgtgaa tctttctact gaaggcacgg tcgattggac gcattggggc ctgagtacag
    34801 cgacaagctt caatcacaag agtggcgtta cttcacagat cagcaatttt tcggcagtcg
    34861 gtggaggggt cgccgggcag tacagtgaca acctcgtggg ctatacctgg accggaggta
    34921 cgccaacagc aagtgccacc aatagcacaa ccgggcttta catcgtggga gtgaataaag
    34981 gcttccaatt taccgtgcca gccgatacta cccaacggac ggtgaaagtc tatgtcagcg
    35041 cttggggtgc gcagggcaaa atggaggcgt ttctcagtga cggtagtgcc gcaggatatt
    35101 cggacacctc gctgagcgat ccgggactga gcagttctgg tgcggctcgg gtctatacgt
    35161 tcacgtatcg agccgcctca gccaaccaaa ccttaactct gcgctggacc aatttggtcc
    35221 aaaacgatcc agctggaggc aatgttacct tacaagccgc caccctcgtt acgacctcag
    35281 ggggaggaag tagcggaacc gcctatcaag acttgcgcta tgtgtatggt ttgaatggga
    35341 atgtgaacga tatctatgac aacctggtgc cgggaggagc cggggatcaa cacctgagtt
    35401 atgacgggtt agatcgtctc acgttggcca gcgggcccta tgggacgaac ggggcgacgg
    35461 cctcgttgac ctgcacctat gatgagctgg gcaacctcac ctttaactca caggtgggca
    35521 cctacgccta tcccgcgagc ggctcgagta gtgttcggcc ccatgcggtt acgaccgccg
    35581 gcagtaatac ctacagctac gacgccaatg gcaacctgac cagcggggcg ggccggtctt
    35641 tgacctacaa cctcgaaaat aaaccgctga cagtcgtgat cagcggccag actaccacgt
    35701 tcgtctatga cggagacggc gggcgggtga agaaaatcgc gggaaccacc accacgcgct
    35761 atatcagcaa gttctatgag tgtgacaaca cgagctgttc acggatggtc tttgccggcg
    35821 gccagcgtat tgccaccatc ggagccagtg gctctatcta ctactatcat acggaccatc
    35881 tgggctcctc aagcgtgatc accgatagtg ccggcgcgaa agcccaagct gtcacctact
    35941 ttccgtatgg cgcgacgcgt acgaacaatt ccacggctac accggccatc gatgtgccct
    36001 acaaatacac gggtaaggag ctcgatagca gcacgaacct ctactactac gaggcgcggt
    36061 actacgatcc cacgttgggg cggttcttaa gtgcggacac gctggtaccg aatccgctgg
    36121 acccccagtc actcaatcga tatagctatg tgcataacaa tccgttcaag tatacggatc
    36181 cgacgggaca cttcaagatc aacgtcggca aatttttaag gcggtcattg ggagatttgg
    36241 gaactggaat tgccggagtc ctgggacaaa cgttaggaaa tgccctctat tggagcggta
    36301 atccaatcct gggctccttg gttcaaggct taggcacagc aatgcttaca caatctaagt
    36361 ctggtcgtta tgttctggca ggtgagataa ttgttacgac agttgtactg tattcggttt
    36421 gtcctggttg tgatggcggt gccgcagcta gcttcatcgg accgatgacg gctgctcagg
    36481 cgagtgcggg ggcgacggcg gcgtctgtat gggggggagc agcagcaggg gccattggag
    36541 gggcagctct tggaggttat agcgctgcca agaatggtgg agatatcagc agtggggttc
    36601 tttttggtgc aacaattggg gcagcttctg gtgccttggg aggagggctt gcacccgctc
    36661 ctggcatgtt cggtacaaat ctccacgggt ggttggcgca aacgattgcg aaggggctca
    36721 tcactaactt tgggtccgga gcaattagtt cctacgctgg tggcaaaggg aatattggaa
    36781 atattctgat gggagcaacg atgaatgccg ctctcggaac ggctaccacc cccgcctcag
    36841 acctgttttg ggggcagatg gttccggaag tcatgggata tctccccgcc actgatatgg
    36901 aaccgtacta tatcaataat gctgagggag ttcccgtacg gggccctgaa ccatatgccc
    36961 catttaatac ggatcttggg aaaagactta ctgggatgat gggcgatgca ggcgcgtcta
    37021 cattcggtga agtatacgga gagaagttgg gagatattat tcatgggcga cctatccata
    37081 taccctaggc aatgaaggaa tggagctgac agttgtcgag tagtgctacg tggtaggttg
    37141 tcaaagccag gcggtccgct gaggatagtc agatctcgga cgccttacct tattttgatt
    37201 gggccgttga gttgggtcct atgagggacg ggtgacgttg gctgacgaac tcgctcggcg
    37261 tcaggtggcc gagtgagctg tgaggccgac gctgagtgta gtccacgcgc caggcttcga
    37321 tgatggcttc tgcctcggcg ggcgacgcaa actgatgcac gttcaagcac tcatcacgga
    37381 gccgcccgtt aaacgattca atgaaggcat tttccaccgg tttgcccggt cgaatgaagt
    37441 cgagttg
//
LOCUS       DAOQPD010000029        36949 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_464_length_36949_cov_24.182713, whole genome shotgun sequence.
ACCESSION   DAOQPD010000029 DAOQPD010000000
VERSION     DAOQPD010000029.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 36949)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 36949)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36949
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_464_length_36949_cov_24.182713"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..196
                     /locus_tag="PK063_08805"
     CDS             <1..196
                     /locus_tag="PK063_08805"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97189.1"
                     /translation="DTSCFIRDRQFGKVKVKLNTAARETGQERNRLFREWEGSGQPKE
                     HGGGTLFLPRIGADLRVIVS"
     gene            complement(189..710)
                     /locus_tag="PK063_08810"
     CDS             complement(189..710)
                     /locus_tag="PK063_08810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003111216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HMZ97190.1"
                     /translation="MLKQVKGQKGFTLIELMIVVAIIGILAAIAIPNFLRYQAKSRQS
                     EAKTNLGAIFVAETAYLSENSRYGSFSEIGYALAGTTNRYTYRSPAILGNGASSNTVG
                     VDQIPCGAPVGCTVQSDASPAVPSLASSTAGSVGFTASAVASIDNDPTIDGWSVNDIK
                     GGLTQAVPDDVIS"
     gene            complement(965..1492)
                     /locus_tag="PK063_08815"
     CDS             complement(965..1492)
                     /locus_tag="PK063_08815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003111216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HMZ97191.1"
                     /translation="MVTESKQAGFTLIELMVVVVIVGILAAFAIPNFLRYRAQAMQAE
                     ARTNLAGIFVGEMSFFTERKEFGNFTDIGFAVAGPGTNRYTYRTGLGLGAGLGPNGGN
                     LCGSAGNCDTIQSEVPAAGAISFTGSVGIATTSSAGFTATAAADLDGDSTHDGWYVND
                     SKQGLSAADPNDVSS"
     gene            complement(1880..3736)
                     /locus_tag="PK063_08820"
     CDS             complement(1880..3736)
                     /locus_tag="PK063_08820"
                     /inference="COORDINATES: protein motif:HMM:NF025912.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ97192.1"
                     /translation="MQRLSEERRQSCTLCKPVGPKAAAVMLIALACVTAACQTAAPSR
                     STQPVVPAAAPPVSRPLSPASDSRASYHFLLGYQAELEQETEQAIKEYQLALQTDPSS
                     HYLKARLAVLYFTAGDVPAAVRFADEVADAPGLDAQMLGQIGGMYAAAGKPDKALRLF
                     NRAIEQEPQRSEHFFAKGLLLANQKQYAEAEETIRSGIKVSPDSAVGYYYLGRIGVEA
                     RDFDKATTHFEQAVTLNPAFEPAYVALGSVYEAKQDRGKAIDIYRRYLQGVNPKNREI
                     RHHLIRLQVSAKQYDEALRELQEMLEEDPSDLDAQLRMGLVYGEQKNYPKAIQQLTQI
                     LTVRPSELKVRDYLGYLYEETKDYAHAIEAYRHNLTLEPSYFEGHLHLGVLLYRTKQY
                     PEAIQHLKEASRLNPKQPEAYIVLGLSHFQVEQYEPSLQAFLEGIRHNPDNADLHFNA
                     GTAYDKLNRFDDVVKSMETTLTLDPHHADAMNYLGYSYAERGVKIEEAIALTKQAVAL
                     RPTNGYYVDSLAWAFFKKGLLSEALAEMKRAVALVGDDPVIYEHLGEIHLKQQHLSDG
                     REALLHALELDPSNDKLMQRFRELGLGDPAKEERIRQAIRRVTERKTAPSAQ"
     gene            complement(3818..5173)
                     /gene="dnaB"
                     /locus_tag="PK063_08825"
     CDS             complement(3818..5173)
                     /gene="dnaB"
                     /locus_tag="PK063_08825"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HMZ97193.1"
                     /translation="MKSLSAVDLTAPRLPPQNIEAEQSVLGGILLDNTAMAKAMEVLT
                     DQEFYRTAHRKIYQAMLELSDRGEVIDQITLTECLKGRSELDAVGGSAYLAELVQAVP
                     TAANIRYHSKIVRDKALLRGLIETSTEVITRGYDGTAAVDELLDFAERSVFGLAQGKL
                     DRSFTQVNHIIKESLDVVDKLSKRKERVTGVPTGYIDLDDLTAGLQPSDLIIVAGRPS
                     MGKTSLALGMAQHAALHAGTVVGIFSLEMSKPQLVLRMLSSEARVDSHALRTGRLQKE
                     DWWRLAEAAGKLEQAPIFIDDSGAVTVQQMRGKARRLKAEKGLDLLIVDYLQLMQGKS
                     DSESRQQEISDISRSLKSLAKELNVPVIALSQLSRAVEARKPPVPMLADLRESGAIEQ
                     DADVVMFIYREEVYEPNTERKGIAEILVSKHRNGPIGKRDLFFHDRFAKFENLETRES
                     V"
     gene            complement(5170..6294)
                     /gene="hisZ"
                     /locus_tag="PK063_08830"
     CDS             complement(5170..6294)
                     /gene="hisZ"
                     /locus_tag="PK063_08830"
                     /inference="COORDINATES: protein motif:HMM:TIGR00443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003879 - ATP phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HMZ97194.1"
                     /translation="MGSLSLKASASSTSLVAGRERSLIPVGMSTILPAAARRIRHLEQ
                     TLLAVLARGGYDEIILPMFEYLDVLAPGLEPELLEKCYQLVDRTTGRLMVLRPDATAQ
                     IARTVAMGMMGERLPLRLCYRTSVFRYEREHAGRDREIFQVGAELIGVDGVTGDAEVL
                     TLLLDCLSQVGLSAFKVAVGHVGFFTALLVRSGLSSEGQKRVEQAAARKDIPLLEELL
                     AREGLARSTGRIILEVLELCGGPEVLSRGRKLVGRDKVLLKPLDRLAQVYERLVSPGQ
                     ESVLIDLGEFRGFEYYDGIVFDVFAPGIGAELGGGGRYDHLMGRFGRTAASSGFALDV
                     DRLFRAIDSSVRPLPPDATRSQSKRRPATPPPSRRPRSRA"
     gene            complement(6313..7905)
                     /gene="serA"
                     /locus_tag="PK063_08835"
     CDS             complement(6313..7905)
                     /gene="serA"
                     /locus_tag="PK063_08835"
                     /EC_number="1.1.1.95"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004617 - phosphoglycerate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006564 - L-serine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HMZ97195.1"
                     /translation="MKILVSDSLSKQGVEVLEKAGFTVVVKTKLPKEELLKEIKDADG
                     LIVRSGTKVTAELIAAASRLKVVGRAGSGLDNVDTPAATRRGIVVMNTPGGNTVTTAE
                     HTMAMIFSMSRRIPQATASTKGGKWEKEKFMGVELYNKVLGIVGVGQIGGYLTKLAQG
                     VGMQVMAYDPYLAPERAQKMGVSIVELDELFRRADVISVHTPLTPETKSLINAQAIAK
                     MKTGVMIANCARGGIVHEGDLCEALKSKKVAAAAFDVFEDEPVKSDNPLLALDNFICS
                     PHIGASTTEAQENVAVGIAEQIVEYFTKGIARGAVNIPSVSPELLPQLQPYLSLGERV
                     GLLQAQLLEGGLERLTVEYSGEVAGLNVAPLTIAVLKGLLTPILEDPVNYVNAPVVAK
                     ERGIEVKEVKSNDAGDFTSVIRVRVEAGKKSHQVAGTLYHRKDPRIIEIDEFKVEVVP
                     DNHLLLVLNEDRPGVIGTVGHILGDHNINIARMQCSREERGGKALLIFGLDAPLPAPV
                     LDQITNSKHILSVKVADLSKGL"
     gene            complement(7934..9079)
                     /locus_tag="PK063_08840"
     CDS             complement(7934..9079)
                     /locus_tag="PK063_08840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HMZ97196.1"
                     /translation="MLKRYLLAPGPTPVPPEVLLAMARPMIHHRAPEFDKLFAEVRED
                     LKWLFQTRNDVLILAASGTGGMEGSVSNFLSPGDKALTINGGKFGERWTKLCKTFGAQ
                     VTELKVEWGRAIDPQAVADALKKDPSIKAVYVQASETSTAVAHDVKALAEIVKQYEDT
                     ILVVDAITALGVLDLKTDAWGLDVVITGSQKALMLPPGLAFASVSEKAWRLADKAKNA
                     AFYFNFKRERENQQKSTTAYTPAVSLILGLKEVMNILKAEGLEAVFARHAMLATAMRE
                     GVKAAGLSIFPQERPSDALTAISAPEGVDGQAVYKNLRTQYGMTAAGGQDHLKGKIFR
                     ISHMGYIDSFDVITALAAVEMVIKGLGYPVKLGSGVAKAQEIIMGKS"
     gene            9494..10795
                     /locus_tag="PK063_08845"
     CDS             9494..10795
                     /locus_tag="PK063_08845"
                     /inference="COORDINATES: protein motif:HMM:NF013618.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HMZ97197.1"
                     /translation="MQTEPALTSEVPAVPLPDSLQPPAQEPDYLLEEEDRTAAAESEA
                     AEDPAAVASEPSTEIPPAEALLQLKPLSGTTARFADLLTPPAEVIQEAAVEQGSESDN
                     VSEYNVPIVLDPSVQGHIRFFNVAIRNRFEQWLIRLSHYRPLVDSIFSEFQLPSDLIY
                     LSLVESGFNPHAYSRARAAGPWQFMKGTAKVYGLRVDSYVDERRDPVKSTVAAARYLR
                     DLYDLFGTWPLAMAAYNAGEGKVMRALHTAQAESFSDIAKTRLIRRETKEYVPRFMAA
                     TIIAKNPDRYGFPQNDVRPHQFEEVVVRRPIHFKAIANVTGISYQELKVLNPELRRDA
                     TPPDDPEYHLKVPVGTREKVEQLLERAPTHKFPPLPMPVQVKGRHFKNETDSGHWYRV
                     RVGDSLEKIAKRFNISVKTLKSNNNLTGPTIKAGSRLVIAN"
     gene            complement(10832..11668)
                     /locus_tag="PK063_08850"
     CDS             complement(10832..11668)
                     /locus_tag="PK063_08850"
                     /inference="COORDINATES: protein motif:HMM:NF024915.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ97198.1"
                     /translation="MSYRIRVPAKVDPLDEAHLLTGVDRVLHVLQEQRRAVLAGLGVV
                     LVAGAVVAGVMWYDYQSTLKARELDQEATLHYLNRPADDPKKSQEQLSQAIALYKQVV
                     EQYPRSPAAPLALFHLGNAQVLANEVDAGIETYKRFMLLYGSNTSLLGLVQQRLAYAY
                     LAKGDRDQAVKAFTGILDVPGALNKDHVLFELAKIEESQSRPEGALAHYQDLMKNYPN
                     SPFTSEAAVRVKVLEVKKAPETPAAAPAPAPAASAPASQPEQPAKASTGKSAASSSKK
                     KQ"
     gene            11752..12942
                     /gene="bioF"
                     /locus_tag="PK063_08855"
     CDS             11752..12942
                     /gene="bioF"
                     /locus_tag="PK063_08855"
                     /EC_number="2.3.1.47"
                     /inference="COORDINATES: protein motif:HMM:TIGR00858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008710 - 8-amino-7-oxononanoate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="8-amino-7-oxononanoate synthase"
                     /protein_id="HMZ97199.1"
                     /translation="MFGLVKARAPMFEKHLQKLDDQHLLRRLRTIASATGPTVTLDGR
                     DIILLSSNNYLGLATHPTVVNAAIEATRRYGAGAGAARLVCGTLTPHETLERTLAGFK
                     GTEAALTFAAGYLANISVIPALIGKDELILADRLCHASLIDGCRLSGATFRVYHHRDM
                     NHLEQLLARRPAGRRTLIVTDGLFSMDGDIAPMKDLVQLAERYGAELYVDDAHGTGIL
                     GRTGRGTLEHCEVESRVPYHMGTLSKALGSAGGYVTGSATFIAYLVNTCRAFIYTTAP
                     PPATAAAATAAIQVIEQEPQRRASLWRNRERLAQGLLRLGFRLAASESPILPVIIGDP
                     DRAMKLAQALLAQGVYAPAIRPPTVPPATSRIRFTITADHTDEQIDRALIAAEQAGRS
                     INLI"
     gene            13144..14199
                     /locus_tag="PK063_08860"
     CDS             13144..14199
                     /locus_tag="PK063_08860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043107 - type IV pilus-dependent motility
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HMZ97200.1"
                     /translation="MIDISKLLTFGVQQGASDCHISAGEPPMIRLHGDLKKLDHPPLT
                     QDETHALIYDMMSDAQRKNFEEHRECDFSFDLGDIARFRVNVFVQGRGLGAVFRTIPT
                     EILPLEKLGMPPILRQLCDREKGLILVTGPTGSGKSTTLAGMIDYLNNTFEGHILTIE
                     DPVEFVHKSKKCLVNQRELGVHTLSFANALRAALREDPDIILVGEMRDLDTIQLALTA
                     AETGHLVFATLHTSSAPKTIDRIIDAFPPNQQAQVRAQLSETLEAVLTQTLLKKKSGG
                     RIAAVEIMVGTTAVRNLIREGKLHQIPGIMQASQKDGMQTMDMALVDLATRGMVTKAE
                     AQSRSMNPNLFNTAGAA"
     gene            14249..15412
                     /locus_tag="PK063_08865"
     CDS             14249..15412
                     /locus_tag="PK063_08865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043107 - type IV pilus-dependent motility
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilT/PilU family type 4a pilus ATPase"
                     /protein_id="HMZ97201.1"
                     /translation="MDVRTLLEVMVKQESSDLYLTVDAPPIYRIHGSTHRTDAPPFTN
                     EQLESLALALMRGQQRGEFEEKMEMNLALYYKDLGRFRVNIFRQKGNVGLVFRHIKAE
                     IMTVEQLDLPPIVKDIAMTKRGLVLVVGATGSGKSTSLAAMIDHRNTVHAGHIISVED
                     PIEFVHHHKKSIVTQREVGFDTHSFGNALKNTLRQAPDVILIGEIRDTETMEAAITFA
                     ETGHLCLGTLHSNNANQSIERIMNFFPVERHAQIYLQLSLNLRAIISQRLIPSLDGRR
                     VPALEIMLDTPRIKDLIKRSEIDTLKEAMEQGIDEGCQTFDHVLLQLYKAGKISIEQA
                     LINADSANNLRLKIKLAGLKGDDAVAALLDKNERDEKGFQIQGQMSQGGGKKR"
     gene            complement(15477..15983)
                     /locus_tag="PK063_08870"
     CDS             complement(15477..15983)
                     /locus_tag="PK063_08870"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97202.1"
                     /translation="MVAPNDSSSVPPSQHNHKAIAALVAGLVLLLALVGIQNAPPPSA
                     VAPAVPNIDPNMVPLVTGEEPIQELFVRAGCVVCHRIPGIVGADGKVGPPLWLGKTGA
                     SRLADPQYRGQAQTVREYIVESVVSPGTYVVPGFPADTMPVWYGRKLTAGALDKIAAY
                     LELATDEP"
     gene            complement(16088..16939)
                     /locus_tag="PK063_08875"
     CDS             complement(16088..16939)
                     /locus_tag="PK063_08875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
                     /protein_id="HMZ97203.1"
                     /translation="MRLFSVTAVLSAIMLVGVGMASAAEPQAAASGTSAEGIKGKDGA
                     PMVLIPAGPFTMGSNDGLPAERPEHTVTLDAFYIDRYEVSMKHYRSFLVEAKHDAPPT
                     WDDEAAETVGDRPAVGMGWADAKAYCAWAGKRLPTEAEWEKAARGTDGRRYPWGQMQP
                     FVDIANYNRGVWVSEAVTLTSVSGGVEGMSVRHGLKEGGRSPYGLHHMAGNAAEWVAD
                     WYDREYYSKSPEKNPTGPETGEKKVIRGGSWSDLPVALRSSARVSAEPDFQDRAIGFR
                     CAMTPGL"
     gene            complement(17189..17683)
                     /locus_tag="PK063_08880"
     CDS             complement(17189..17683)
                     /locus_tag="PK063_08880"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97204.1"
                     /translation="MSKHRGFCFTLLLLLVGVVEGCTTMPSGTSTVLPSSAFFPLDAS
                     ELKPLQAIAHAQDARMKNCHKGPACEDAYYTRALVALFENRADAITVFQELRTAMPNS
                     RYEVATVGWLNLLQDASLSSDHNKALMVQLKQEVLHNLLDRSEVATARPVKDHDRRVA
                     ELAR"
     gene            complement(17964..25280)
                     /locus_tag="PK063_08885"
     CDS             complement(17964..25280)
                     /locus_tag="PK063_08885"
                     /inference="COORDINATES: protein motif:HMM:NF018319.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding protein"
                     /protein_id="HMZ97205.1"
                     /translation="MSSNTTAWLNFALQQMAAESYLQDIDLHNELLVKPRLLLGNNNQ
                     FGISPTDADLAGKTRFTSVLADRFLARYDIVDHHASDATGFSATLLFDKETQQYTLSI
                     RSTEYRDEAQGGDWQRDGLPGADGEIKDYGFALAQLVSMERYWRELTAVGGKLAPDAK
                     INVTGYSLSGHLATVFTEMHSDRILQTYTFNGAGRGFVSELGQDGQPVEQTLRRMMLD
                     LEGRLLAFDPEGTQFRSGAAGNIYGDARYDVARQATLTRFPTIGTGNTQFFTIPAGVV
                     GGIPTQSEALDKVVQLVGNAETGSDVQFVANSGIHAPSQSIFIEGQPLLEGFNQQREF
                     QYGNTHSLTLLVDSFALQELFLKVDPTLEQSQIEGIFNAVSAQKADVTVLPGVIPLAE
                     GDTLEKTLDALRKVFLGNVSSTPFGRQPGDFGNLGNRDAFYQNIQQVTAALTGVSYRI
                     DSLVGQSASTMRTIALQDGPNDALGLAYRYALKELNPFVLRGMDRDTTQALYSRHNET
                     GELSLLDPNTGTGNLTSLYFEDRAAFLLKKIEVDSHSISLPSLTHFNDIELGYELGSD
                     ALPLPQVLFGGQGGDSLIGSLLFVDHLYGGQGKDQLYGNGGKDYLEGNQEDDLLDGGS
                     GADTMLGGTGDDIYIVDNIGDVVREYANSGRDEVKSSVTFTLDSQVENLTITESSARN
                     GTGNELENTIVGNSAINILSGLGGQDHLVGGGGNDILLGGTGDNDLLEGGIGFDTYIY
                     HSGDGMDRIEDSDAQGQIVFDARLLQGGIRRAGDGTNTYTSLDGQTTYVMSGTDLIVN
                     GVLIVNENFQSGQMGIQLRDVSAMPRDTGVPAGHFTDTYIGGADAEEWVPGAGAIEVY
                     ANGGNDVLHGDHAPILGAFDDLLDGGAGNDVFFGGYGDDYLIGGYGDDYAFVTDGDMF
                     LGGDGDDYAVGTANYLSFAEPIIGGGAHYADGGAGNDTLMGEMGADVLLGGDGDDVLR
                     GENRPTGWIGLAYDNSFWNRTPQAGIISLSGGNDYLDGGAGSDLLVGDGGDDILLGGA
                     GDDRLYGESDFTLTIAGDDWLDGGEGNDSLFGGAGADMLSGGDGDDLLVGDFSGDPGS
                     ADILDGGAGADELQGGGGDDILYGGIGMDRLAGFGGNDFLDGGADNDELQGGAGDDSL
                     WGGLGNDRVTGQEGDDTLFGDEGDDELQGDAGGDTLFGGEGHDALFGQDGDDLLSGEA
                     GDDLLNGGLGNDQLDGGDGIDDVQGREGDDFLVGGDGSDFLYGDGNNPTVLSLAGGND
                     TLDGEEGDDQLWAGAGQDQLFGGEGSDQLVGDAGDDQLYGEAGNDFLFGDSPFFSTQA
                     GSDVLDGGEGDDTLQGGGGEDDLQGGRGNDLLIGGSGLDTYRFNLGDGADTIQDDGVQ
                     RNRLIFGAGITAESLRLDVGPADTLVLRVGNDEDVIRVSNFGLNDPAEFHTIRQFEFA
                     DGTVLTDGELLARGFQLSSPETGGTLQGTSFDDRMQGSQVGDLLYGRGGNDVLLGGVG
                     DDVLQGDEGDDELDGGAGNDRLYGNQGFNVLRGGEGNDILESVGLGDQLLGGGGDDAY
                     HLRSMGQVITEEVNAGRDTIYLTPTESLTFQAPDNFENVRIEDDVYLDSTVQVNLVGN
                     ALDNELSGSHRLDGQAGNDTLIGTGDNTFVFGPGYGQDVVRTGLQVYAHSGLDQVQFL
                     QGVTPSNLSLERQANDLVVKVTGTADELRVQSYYESPANMVDQFLFADGAIWTSGEIE
                     NRVRTFIGVGADESFYGSAGDDTIRGMGGNDQIRANAGNDVLDGGVGNDFLEGYSGND
                     TYVFGRGYGHDTIDDQGDSADIDTLQLVDGITPGDITLQATPDFQTDALLTIKNSADQ
                     VTLAGFFQSDGMRVDRIQFSDGTMWDYSAMLAHTEGVNLVGTEDTDYFYGNVTNDTLL
                     GVGGDDVLSGGAGNDTLDGGTGADRMTGGSGNDVFMVDNINDIVMESVGQGIDTVYSS
                     LTYTLGSNLENLTLTGSAAINGTGNSLNNILTGNSAANVLTGGAGNDTYVVGLGDTVV
                     EAASAGTDTVRSDISWTLGTNLENLILTGIAAVNGTGNSLANTLTGNSAANILSGLAG
                     ADTLIGAQGDDLYIVDNVGDKITELAGEGLDTVQSSVTYTLSANVENLTLSGTSAING
                     TGNGLDNVIIGNSAANQLVGGAGNDTYVIGSGDTVVEGINAGIDTVQSSVTHTLAANV
                     ENLTLIGTGAINGTGNALNNILVGNNATNTLTGGAGDDTYVVGTGDTVVEALNAGLDT
                     VQSTVTWTLGANLENLTLSGAAAINGTGNTLANSLIGNAGNNVLMGGDGNDTLSGGKG
                     NDVLNGGTGNDLFQVARGDGQDTITDASGSSDRLSFASGINPLDLMLSQSANDLRIAV
                     YGSTDQVTITNWYAGAANQIETVQAGNGQQLMSTQVNQLIQAMAGFTQQTGLSWDQAI
                     AQRPQDVQQILAANWH"
     gene            complement(25270..26271)
                     /locus_tag="PK063_08890"
     CDS             complement(25270..26271)
                     /locus_tag="PK063_08890"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97206.1"
                     /translation="MKQNRRMLSLFVIAGLLSLALIAPTGAGLFGKDETVGERFRKAI
                     EKIKQSCESRKLARGEVCGEVAKLKPADPLATEEGRFAHSIKIPNPVPEDSGYKPGMT
                     SQEYFEHLCKTEAGEFIYKTAENVEGLYMMRPREHANDYMQEHLYAMEDPYGYMDAES
                     QDPEFFFVGPLRYKFFEHPLAPRKKPSWGKSFLDNSYFTAPSDRAYHERYLGSNGKDP
                     LTMIKEFDSVRKARYGYTWRGIVRPHDREMGIAGGELIVLDMETGEVLGVRRGYIRTG
                     SVRNNLTGVWWLTGQACPYYQHRGGRSRDFDFSYWFIGKVVKPINYEMNVRELMNVK"
     gene            complement(26324..27718)
                     /locus_tag="PK063_08895"
     CDS             complement(26324..27718)
                     /locus_tag="PK063_08895"
                     /inference="COORDINATES: protein motif:HMM:TIGR01843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030253 - protein secretion by the type I
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family type I secretion periplasmic adaptor
                     subunit"
                     /protein_id="HMZ97207.1"
                     /translation="MMNALQLKLAGWRTIGRVGSGQSSHAAAQGEAIEFLPAILEIQD
                     APPSPIGRAILWTIMLAFASAVTWSSLSQVDIVAVAPGKIIPSGYSKTIQPFETGVIA
                     AIHVQDGQSVKRGEVLIELDATQNSADRDRASNEYRAALVEAARLHALIAGHSTFTAP
                     SESDPEFVLLQQQLLRDQMVEYAARVDAARHLIGQRKAAVDAAKDNLRRLEATVPMEN
                     ERAAAYRALLAQQYVSKMDYLQFEQQRIDKAQEWAGQKSKLRQDQAALAEAEQNYQVL
                     ISEFQQSKQAELSAMETKATSLVQEVRKAGQKTELQSLVSPIDGVVQQLAVHTVGGVV
                     TPAQTLLMVVPQDHPVEVEAQLENKDIGFVKEGQPVELKIETFPFTLYGTIPGKVLTV
                     SDDAVPLDKEKGGLVYVSRVSMDRATMQVEGKHVHLTPGMAVTVEIKTGQRRVIEFLL
                     SPLLKSMKESLRER"
     gene            complement(27718..29880)
                     /locus_tag="PK063_08900"
     CDS             complement(27718..29880)
                     /locus_tag="PK063_08900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030253 - protein secretion by the type I
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I secretion system permease/ATPase"
                     /protein_id="HMZ97208.1"
                     /translation="MDVPTSHLESCSTAPPRPDTGLLCLLLIARFHDLPIDSGQIQHQ
                     FGLSGHMLTTNALVRAAKHVGLKAGLVSSSWGELAGAPLPAIAQRTDGTYVVLAKVQG
                     EKALLQDPLKERPHILSKEEFVACWSGSLLLFTKRSGLRVEDVSFDMTWFIPAVLKYR
                     RLLGEVVLASFFLQVFALLTPLFTQVVIDKVLVHKGFTTLHVMAVGMLALALFDALLG
                     GLRTYLFAHTTNRIDVGLGAQLFRHLLALPLAYFEARRVGDTVARVRELEQIRQFITS
                     NSVTVVLDVVFTIVFLGVMWIYSPTLTLVVMASLPLYALLSVLITPAIRARLHEKFNR
                     GAENQSFLVEAVSGIQTVKALAVEPPLQRRWDEQLAGYVAASFRATSLITVAGQIATC
                     IQKSTTIAIMWVGAYQVIDGALSIGELIAFNMLSGQVTGPLLRMVNLWQEFQQVGISI
                     QRLGDVLNAKLEPSYNPNRTTLPQIAGQIVFDDVAFRYRVDGPLVLQRVSLTLHPGQV
                     VGVVGRSGSGKSTIAKLMQRLYVPERGRVLVDGVDLAQIDPAWLRRQVGVVLQENFLF
                     NRSVRDNIALTDPGLPMDRVMHAAKLAGAHEFILELTDGYDTVVGEHGCALSGGQRQR
                     IAIARALVANPRILIFDEATSALDYESEAIIQRNMAQICKGRTVIIIAHRLSTVRPAH
                     KIYVIDRGQLVEQGTHDELLSRDGMYTRLHQHQQGRAA"
     gene            complement(29902..30237)
                     /locus_tag="PK063_08905"
     CDS             complement(29902..30237)
                     /locus_tag="PK063_08905"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97209.1"
                     /translation="MAVGSSPKQNGDKAVAVNVRLQSSTEADQPILANYSHASLAQGL
                     AYIDFGFLEPSLIGAVAQRAQKGEAMPKQLVGSRAVRVALPLDALIRLHQQLQQMVAS
                     LQPAKSKLS"
     gene            30595..31179
                     /locus_tag="PK063_08910"
     CDS             30595..31179
                     /locus_tag="PK063_08910"
                     /inference="COORDINATES: protein motif:HMM:NF019819.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin family protein"
                     /protein_id="HMZ97210.1"
                     /translation="MQKVLMLQAGWRTLCPVTALCLSLSACAGVSTTDTLPTVASVDL
                     ARYAGTWHEIARLPMWFQRHCVDSKATYTVRNDGAIGVRNECVTDTGGHDEVEGVATV
                     VDPGTNTRLRVVFDNFFARLFGSSREGNYWILALDADYQTAMVGTPDRRYLWILSRSR
                     QLDETAYTRLVEQARRLRFPVSELIRPHRSAATS"
     gene            complement(31271..32176)
                     /locus_tag="PK063_08915"
     CDS             complement(31271..32176)
                     /locus_tag="PK063_08915"
                     /inference="COORDINATES: protein motif:HMM:NF015587.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HMZ97211.1"
                     /translation="MWALLKSLATQTIAKWSDEPGPRFAAALAFYTALTIVPLVVLTI
                     MVSVSMVGDESMVGGLQRQIGELIGESAANGLFRIIAQWRSAGSPLVNGVVALGVFVI
                     GALKVMDQLRDALDCIWGLQPKHPPRMGDRLKRRFASLSGLFGIAFILLASLTLSAWT
                     GIAIQFVLETTGMPGRLVQGIGLLMSFGVVSTLFAMIYKWVPQAQVAWSDVWVGAGIT
                     AILYLLGSKLLVVYLAHNTLVAFYGAAGSLVLVLLWAYYASQVFLFGAAFIAVYATHH
                     GSQVKPTEETVVVHVASQGESETEG"
     gene            complement(32339..32563)
                     /locus_tag="PK063_08920"
     CDS             complement(32339..32563)
                     /locus_tag="PK063_08920"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97212.1"
                     /translation="MDKAQNLASAARANLNSEMQGYADALQRIIDLARNGAMLGHDHA
                     YDACCKIEAIATEALQRPTTPHRPDDKPTG"
     gene            complement(32725..33060)
                     /locus_tag="PK063_08925"
     CDS             complement(32725..33060)
                     /locus_tag="PK063_08925"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97213.1"
                     /translation="MMKVPTYVSLVLCIAVLGGCNYSDGDRTGYLQKLSRKGWVCKTY
                     EGELAMTTVPGVAPVLWNFSVWDDDVAKILDGQMGKRVVLHYREFRYVPTTCFGETSY
                     FIDRAQVSE"
     gene            33269..33727
                     /locus_tag="PK063_08930"
     CDS             33269..33727
                     /locus_tag="PK063_08930"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97214.1"
                     /translation="MIATLATALLVVLATVPNGHAVAQSSQRDVFDERDTRVFKAVGC
                     TQDKQPAEALYYIVASRSDLSAGVPSPSAQFMKDEVEQNWQRIASQLTMEQVTEERFT
                     DTYHALLNDMIPRLQRAVEEKSGVSIAVSEVNSRPMDRTKDQDVPTCSSQ"
     gene            33995..34147
                     /locus_tag="PK063_08935"
     CDS             33995..34147
                     /locus_tag="PK063_08935"
                     /inference="COORDINATES: protein motif:HMM:NF023180.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3309 family protein"
                     /protein_id="HMZ97215.1"
                     /translation="MSTILLIILILLLIGALPSWPYSSGWGYYPSGGIGLILLIVLIL
                     ALTGRV"
     gene            complement(34254..34574)
                     /locus_tag="PK063_08940"
     CDS             complement(34254..34574)
                     /locus_tag="PK063_08940"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97216.1"
                     /translation="MSLKIDVTTVARVLLRDGSWYEVIPGSLTMDTFQWTDREGITIA
                     SVDLEALPPMGIRFKTRGMSGWLSCPLTSIVAVHYEPIELEDPLAVELPSLLSDELDR
                     PSVQ"
     gene            complement(35058..35813)
                     /locus_tag="PK063_08945"
     CDS             complement(35058..35813)
                     /locus_tag="PK063_08945"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ97217.1"
                     /translation="MTITPKRILIADDEETFRESTVAILADAGYACNAARDAIEAERL
                     LENGYDLLLADVRMPGNSQLEFLETVARRHPDLPVVVVTGYPSVGTVIESFRLSIVDY
                     LIKPVDLNELKKAVDRGLRRRSIARAVQDAMHETAKMAGIFERLGRSMNEFGGRGQQV
                     EWTAQEYMAQAMGHISQLSALVGRTLEASRTGQPQAPTDICAVMKCPRLDRYEAAIEE
                     AIQVMEHTKSSFKSKELGTLRQHLEDVLREGRR"
     gene            complement(35779..>36949)
                     /locus_tag="PK063_08950"
     CDS             complement(35779..>36949)
                     /locus_tag="PK063_08950"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ97218.1"
                     /translation="IIACNPSAEQILGLTAEQMMGRTSVTSEWRAIHKDGTPFEGEQH
                     PAMVTLHTGQPCADVIMGVCRPGGEQRWLSINTQPLREPHAERPYAVVASFHDITERR
                     RAEQALVEVQTQLEQRVRERTARIHELEAQRSQAEKVAALGHLAADIAHEINNPLAGI
                     KNAFHLVKQGVSPDHRHYRFVELIDREIQRLAAIVKKMYTLYQNGASGQWQATDVSDL
                     LQNVGTLLDYKLVSRRIQLRTEIELTCPVVTLPRADLFQVLLNLVQNAIDASPQDMEV
                     VLKVARHGDTLHWSVMDHGPGITPEVFPHIFEPFFTTKSAGGPQGLGLGLSVSRGLVR
                     AMGGRIEVHTRPAGGSTFTVIHPLNVTDGVGQQGTGAALKKEQEDDDYAKTHSHC"
BASE COUNT         8290 a        11098 c         9437 g         8124 t
ORIGIN      
        1 cgatacctcc tgctttatca gagaccggca atttggcaaa gtgaaagtga aattgaatac
       61 tgcggcgaga gaaacagggc aggaaagaaa caggctgttc agagaatggg aaggatctgg
      121 tcagccaaaa gaacacgggg gaggaacatt gttcctcccc cgcatcggag cagacctgcg
      181 cgtgatcgtt agctgatcac gtcgtcagga acagcctggg tcagaccacc cttgatatcg
      241 ttgactgacc aaccatcgat ggtcgggtca ttgtcaatgc tggccaccgc ggacgccgtg
      301 aagccgactg aaccagcggt cgagctagcg agggacggca cagcaggaga agcatcactc
      361 tgaacggtgc aaccgaccgg cgcgccgcaa ggaatctgat cgacgcccac ggtgtttgac
      421 gatgcaccgt tacccaagat ggcagggctg cggtacgtgt accggttggt cgtaccggca
      481 agggcatagc cgatttccga gaagctgcca tagcgcgagt tttcgctaag gtaggctgtc
      541 tcagccacga agatcgcgcc caggttcgtc ttggcttccg actggcgcga cttggcttgg
      601 tagcgcaaga agttcggaat ggcgatggcc gccaagatac cgataatcgc cacgacgatc
      661 atcaactcaa tcaacgtaaa acctttctga cccttcactt gcttcaacat aatgcctccc
      721 tttcctattg ttgccacttc atccgacacg ttcttgattc ctgtcacttc attcggaacc
      781 gcgtgttcac gcctgacaga tcttgggaat agcaggttct atgcccaaca cctccttcct
      841 gtagttgcgt atctttttgc atatcttcca atcacttaga tttaggatcg cttttgaact
      901 cctcacggct gcctgaacga gattcctttt tccgtcatca ggtgacaagt tttggcaccc
      961 gcacctaact cgatacatca ttcgggtcag cggcactcag cccttgcttc gaatcgttga
     1021 cgtaccaccc gtcatgcgtc gaatctccat caagatccgc tgcggcggtt gcggtgaaac
     1081 ctgccgaaga ggtggtggcg attcctacgc ttccagtgaa actgatcgcg ccagcagccg
     1141 gcacttcaga ttgaatcgtg tcgcagttgc cggcagatcc gcaaagattg cctccgttcg
     1201 gtcccaatcc agccccaagg ccaagcccgg ttcgatacgt ataccgattc gttcctggtc
     1261 cggccaccgc gaagccgata tccgtgaagt ttccgaactc tttccgttcc gtgaagaagg
     1321 acatttcacc gacaaaaatt cccgccaggt tcgtccgtgc ctcagcttgc atcgcttgtg
     1381 cgcggtatcg aagaaagttc ggaatggcga atgcagccaa gatccccaca atcaccacta
     1441 cgaccatgag ctcgatcagt gtgaaccctg cttgctttga ttcagtcacc attgggctcg
     1501 aagactttcg ctctggaaac ccatcctgat gctccgcccg tccgtactgc cgacaggcca
     1561 cgtataagca ggccccatgc caggagagga gccttttaac tgttcccgca taacctgccg
     1621 acaaaccgag gcatttttgt ctagatttca caattctggc cctgttcgct caaacaggaa
     1681 gaggagccga gctaggcaaa gtgccaaaaa ttgactgaat cgaacaggta gagctcgttg
     1741 gctggggagg aagaactgct gcggaagccg ctggaggact atgtggaaac gaacgggatt
     1801 ggcaatgagg tgatgaacaa tcggtggcga tgccctctcg gtatagaggg cacgaggcaa
     1861 ctgtagcgtg agacaagaat tactgagccg agggagccgt cttccgctct gttacacgcc
     1921 ggatggcttg gcggattcgc tcttctttgg caggatcgcc caaaccgagc tcacgaaacc
     1981 gctgcatgag cttgtcattc gagggatcaa gttcgagcgc gtgcaggaga gcctcgcgac
     2041 catcggagag atgttgctgc ttcaaatgga tttcgcccaa atgttcgtag atgaccggat
     2101 catcgccgac gagcgccacc gcccgcttca tttcggccag agcctcgctc agcaacccct
     2161 tcttgaaaaa ggcccaggcg aggctatcga cgtaatatcc attcgtaggc cgtagcgcga
     2221 cggcctgctt ggtcagtgcg atggcttctt cgattttgac tcctcgttcc gcataactgt
     2281 acccgaggta attcatcgca tcagcgtggt gaggatccaa cgtgagcgtg gtctccatcg
     2341 acttcaccac atcgtcaaaa cgattcaatt tgtcataggc agtgccggcg ttgaaatgca
     2401 ggtcggcatt atctggattg tgccggattc cttccagaaa ggcttggagg gaaggctcat
     2461 attgttcgac ttgaaaatgc gacaacccga gaacgatata cgcctcaggc tgcttggggt
     2521 ttaagcggct ggcttccttc agatgctgga tggcctcggg atactgcttg gtccgataca
     2581 gcaagacccc caagtgcaga tgcccctcga aatacgaggg ttccaaggtc aaattgtgtc
     2641 ggtacgcctc aatcgcgtgg gcgtaatcct tcgtttcctc gtagagatac ccgagataat
     2701 ctcgcacctt gagctcggag gggcgcacgg taaggatctg cgtcaactgt tgaatcgctt
     2761 ttggataatt cttctgttcc ccgtacacaa ggcccattcg caactgagca tcgagatctg
     2821 acggatcctc ctccagcatt tcctgtaact ctcgcagcgc ttcgtcgtac tgcttcgccg
     2881 acacctgcag ccggatgagg tgatgccgga tttcacgatt ttttggattc acgccttgca
     2941 agtaacgccg gtagatatcg atggccttcc cgcgatcctg cttggcttca tacacagacc
     3001 ccaatgcgac ataggccggt tcaaacgctg gattcaacgt cacggcctgc tcgaaatgcg
     3061 tcgtagcctt atcgaaatcc cgggcctcca caccgattct gcccaagtag taatacccca
     3121 ctgccgagtc cgggctgacc ttgatgccgg agcggatagt ttcttcggct tcggcgtatt
     3181 gcttttgatt ggccaacaac agccctttgg caaaaaaatg ttcgctgcgt tgaggttcct
     3241 gctcgatggc acgattgaac agccgcaagg ccttgtccgg ctttcctgcc gccgcataca
     3301 tcccgccgat ttgcccgagc atctgcgcat ctagccccgg cgcatccgca acttcatcgg
     3361 caaatcgcac cgcagccggc acatcacctg cggtgaagta gagcaccgct aatcgagcct
     3421 tgagatagtg agaagagggg tctgtctgca gtgccagctg atactctttg atagcctgtt
     3481 ctgtctcctg ctccaactcg gcctgatacc ccagcaggaa gtgataggag gcacgcgaat
     3541 cagatgcggg agacaagggg cgagagaccg gaggagccgc ggcagggacg accggttgtg
     3601 tggagcgtga cggcgcggcg gtctggcacg cagcggtcac acaagcaagc gcgatcagca
     3661 tgacagctgc agcctttggt cccacgggtt tacagagggt gcaggactgc cgacgctctt
     3721 cactcaatcg ttgcacaatt catccgctca atctgcaggg ggaatgttcg gggtacagga
     3781 aacgatgcgg aattataccg gcccgtgaaa gaacgcgtca aacgctctca cgcgtctcta
     3841 gattctcaaa cttggcgaat cggtcgtgga agaacaaatc gcgttttccg atcggaccat
     3901 tgcgatgttt gctgacgaga atctcagcaa tgcccttccg ctcagtgttc ggctcataga
     3961 cttcttcccg atagataaac atcaccacgt cagcgtcctg ctcgatggcg ccgctttcac
     4021 gcaaatcggc caacatcggc accggcggct ttctagcctc gacggcccgg ctcaactgcg
     4081 ataaggcaat gacgggaacg ttcagctctt tggcaagact ctttaaggag cgggagatgt
     4141 cggaaatttc ctgctgccgc gactcggaat cgctcttgcc ctgcatgagc tgcagatagt
     4201 ccacgatgag caaatcaagg cccttctcgg ccttgagccg tcgggccttt ccgcgcatct
     4261 gctgcacggt caccgctccg gagtcatcga taaagatcgg ggcctgctcc agcttgccgg
     4321 ccgcctcggc caatcgccac caatcctcct tttgcagtct tccggtgcga agcgcgtgcg
     4381 aatcaacacg agcctcggaa ctcagcatac gaagaaccaa ttgcggcttg gacatttcga
     4441 ggctgaaaat tcctacgacc gttccggcat gcaaggcggc atgttgggcc atgccgaggg
     4501 ccaaactcgt ctttcccatg cttggccgtc cggccacgat gatcaagtct gacggctgca
     4561 acccggccgt cagatcatcc aaatcaatat agccggtcgg caccccggtc acccgctctt
     4621 tccgcttgga caacttatcc acgacatcaa ggctttcctt gatgatgtgg ttgacctggg
     4681 tgaaggagcg atcgagcttg ccctgggcga gcccgaacac cgagcgttcg gcaaaatcga
     4741 gcaactcatc gaccgccgct gtaccgtcgt atccgcgggt aatgacttcc gtagaggttt
     4801 cgatcagccc tcgtaagagc gctttatccc ggacgatctt gctgtggtac cgaatattcg
     4861 cggccgtagg gacggcctgc accagctcgg caaggtaggc tgatccaccg accgcatcta
     4921 attccgaacg tcccttcagg cattccgtca acgtgatctg gtcaatcact tcgccacgat
     4981 cggacagttc cagcatggcc tgataaatct tgcgatgagc agtccgatag aactcctgat
     5041 ccgtcaggac ttccatcgcc ttggccatgg ccgtattgtc caatagaatt ccgcccagca
     5101 cggactgttc ggcttcgatg ttctgtggcg ggagtcgagg cgctgtcagg tcaacggccg
     5161 agagcgattt catgctcggc tccttggccg tcgtgacgga ggaggcgtcg caggccgacg
     5221 cttcgattga gatctcgtcg catcgggcgg aagcgggcgg accgacgaat cgatagctcg
     5281 gaatagtcga tcgacatcca gagcaaatcc cgaggatgcc gccgtgcgac caaagcggcc
     5341 catcaagtga tcatagcggc cgccaccgcc caattctgcg cctatccccg gagcaaagac
     5401 atcaaaaact atcccgtcat aatattcaaa gccgcgaaac tctcccagat cgatcaggac
     5461 tgattcctgt cccggcgaaa ccaaccgttc atagacctgc gccagtcgat cgagcggttt
     5521 caatagcact ttatcgcgcc caaccagctt acgtccgcgc gacaggactt cgggacctcc
     5581 gcatagttcc aggacctcca gaatgatccg tccagtggat cgggccagtc cctcgcgcgc
     5641 cagcaattcc tcgaggagcg ggatgtcttt gcgagcagcc gcttgctcca cgcgtttctg
     5701 gccttcgctt gagagaccgg acctgacaag aagagcggta aagaagccga catgcccgac
     5761 cgccacttta aaggcgctga gtcccacctg actcaaacag tccagcagaa gtgtcagcac
     5821 ctcggcatcc ccggtcaccc cgtcaacccc gatgagctcc gcgccgactt gaaaaatttc
     5881 ccggtcgcgg ccggcatgct cgcgttcgta gcgaaagacc gaggtgcgat aacacaagcg
     5941 caacggcagc cgttcgccca tcatacccat ggcgacggtt ctggcgatct gtgccgtcgc
     6001 atccgggcgc aacaccatca ggcggcccgt cgttcgatcg accagctgat aacacttttc
     6061 gaggagttcc ggttcaagcc ctggcgcgag gacgtccaga tactcgaaca tcggcagaat
     6121 gatttcgtcg tacccgcctc gcgccagaac ggccagcaga gtctgctcaa ggtggcgaat
     6181 acgtcgagcc gcggcgggaa ggatggtgct cattccgacc ggaataagcg accgttcccg
     6241 acccgccacc agcgacgtgg aggaagcaga ggccttcaac gaaagggagc ccatgatcga
     6301 ctgccgggca atctacagac ctttcgacag gtcggcgacc tttacggaaa ggatgtgctt
     6361 gctgttcgta atttgatcga gcaccggcgc aggcagcggc gcatccagcc cgaaaatcaa
     6421 gagggctttg ccgcctcgct cctcacgtga gcactgcata cgcgcgatat tgatgttgtg
     6481 gtcgccaaga atatgtccga ccgtcccgat cactcccgga cgatcctcat tgaggaccaa
     6541 taacaaatgg ttgtccggga ccacttcgac cttgaattcg tcaatttcga tgatacgcgg
     6601 atctttgcgg tgatacagcg ttcccgccac ttgatgagac tttttccccg cttccacccg
     6661 cacgcgaatc acgctcgtga aatcgccggc atcgttgctc ttgacctctt tcacttcgat
     6721 cccgcgctct ttggcgacga ccggcgcgtt cacatagttg accgggtctt caaggatagg
     6781 cgtcaggagc cctttcaaga ccgcaatcgt caacggggcg acattcagtc cggccacctc
     6841 accactatat tcgacggtca accgctcaag tccgccttcc aataattgag cttgcaacaa
     6901 acctacacgc tctcccaatg agagataggg ctggagctgc ggcaagagct cgggagacac
     6961 agagggaatg ttgacggcgc cacgggcgat ccctttggta aagtattcga caatctgctc
     7021 ggcgattccc accgcgacat tctcttgcgc ttcagtcgta gacgcaccga tatgcgggga
     7081 gcaaatgaaa ttgtccagag ccaggagagg attgtccgat ttcaccggct cgtcttcgaa
     7141 cacgtcgaac gccgctgccg ccaccttctt cgatttcaat gcttcgcaga gatccccttc
     7201 gtggacgatg ccgccacggg cgcagttggc gatcatgaca ccggttttca tcttcgcgat
     7261 agcctgtgcg ttgatgagcg acttggtttc aggggtcagt ggagtgtgga ccgagatgac
     7321 atcggcccgg cggaacaatt cgtccaattc cacgatggat acgcccattt tctgcgcccg
     7381 ttcgggtgcg agatacgggt cataggccat cacctgcatg ccgacgccct gggcgagctt
     7441 ggtaaggtat ccgccgattt gtccgacgcc gacgatcccc agtaccttgt tatacaactc
     7501 cacgcccatg aacttttctt tttcccactt cccgcccttg gtcgaagcgg tcgcttgcgg
     7561 aatacggcgc gacatagaaa aaatcatggc catcgtatgt tcggcggtgg tcacagtgtt
     7621 gccacccggc gtgttcatga ccacaatgcc gcgacgggtt gcggcggggg tatcgacatt
     7681 atccagaccg gaaccggctc gtccaaccac cttcaagcgg ctcgccgcgg cgatgagttc
     7741 tgctgtcact ttcgtcccgg agcgaacgat caacccgtcc gcatccttga tttccttcag
     7801 cagctcctct ttgggcagct tggttttcac cacgaccgta aagccggcct tctccaacac
     7861 ctctacaccc tgcttcgaaa gactgtcgct gaccaagatt ttcattgtcg tggcgcctta
     7921 cctgaaggtg agtctaggac tttcccataa taatttcttg agccttggca accccgctcc
     7981 caagcttcac gggatacccc aaccctttga tgaccatttc cacagccgcc aaggccgtga
     8041 tgacgtcaaa gctatcgata tatcccatgt gcgagatacg gaagatcttg cctttcagat
     8101 ggtcctgacc gccagcggcc gtcataccat actgcgtgcg caggttcttg tagaccgcct
     8161 gaccgtccac accttccggg gccgaaatgg ccgttaatgc atcgcttggc cgctcctggg
     8221 ggaaaataga aagtcccgcc gccttgacgc cttctcgcat ggccgtcgcc aacatcgcgt
     8281 gacgggcgaa gacggcttcc aggccctcgg ccttcaaaat gttcatcact tccttcaggc
     8341 ctaagatgag ggagaccgcc ggcgtatagg cggtggtgct tttctgctga ttctcccgct
     8401 cccgcttgaa gttgaaatag aaggccgcgt tcttcgcctt gtcggcgaga cgccaggctt
     8461 tctcactcac gctggcaaag gccaatcccg ggggcagcat caaggccttc tgcgatccgg
     8521 tgatgacgac gtccagtccc caagcatcgg tcttcagatc gagcactccc agggccgtaa
     8581 tggcatccac cacgagaatg gtgtcttcgt attgcttcac aatttcggcc agggctttga
     8641 cgtcgtgtgc gacggccgta gaggtttcgc tcgcctgcac gtacacggct ttaatcgagg
     8701 ggtctttctt caacgcgtcg gcaacggctt gggggtcgat ggcgcgcccc cactccacct
     8761 tcaactccgt cacctgggcg ccaaacgtct tgcagagctt cgtccaccgc tcaccgaact
     8821 tgccgccgtt gatcgtcagg gctttgtcgc caggagagag gaagtttgaa accgaccctt
     8881 ccatgccgcc ggtgccggaa gccgcgagga tcaaaacatc gttgcgcgtc tggaacagcc
     8941 atttcaggtc ctcacgaacc tcggcaaaca atttatcgaa ctcgggtgcc cggtggtgaa
     9001 tcatcggtct ggccatggcc agtagcacct ccggtggaac aggggtgggg ccgggtgcca
     9061 gcaaataccg tttgagcatg ggacgatcct cctcgctgta cggaactaac aatgtcaggg
     9121 atttagaagg ggcgtacgct accatagccc cccagaggtg tcaaggtaag ttcccaggaa
     9181 gatgcccgtc ttttcagcga cttcactgcc tttaccggag agttgctttc aaaatgttcc
     9241 ggcggacctg atgctgagat cctgaaaggt ttcgttcgcc cagcaactca actccctcaa
     9301 tttcttgaca agaactcacc tcctcgatag gctacgattc gagagtcggt cacctccctt
     9361 ccctgaaccg tctagtaggt accttatgca tgcacgtttt tccagcgctg gcgttccgcc
     9421 cctttccctt cttttcgcat gtctgctctc tgtttcttcg cctggttctg caggcgcgga
     9481 atcgccgatt cccatgcaaa cggagcccgc tctcacatcc gaagttccag cagttccgtt
     9541 accagatagc ctccaacccc cggcgcaaga acctgactat ctcttagagg aagaagatcg
     9601 cacggccgcc gcggaaagtg aggcggccga ggacccagct gcggtcgcga gcgaaccgtc
     9661 cacggagatt cctccggccg aagccctgct ccaactcaag ccgctcagcg gtaccaccgc
     9721 gagatttgcc gatttgttga cccctccggc tgaagtcatc caggaagccg ccgtggagca
     9781 agggtcggaa tcggacaatg tttccgaata caacgtcccg atcgtgctcg acccttccgt
     9841 gcaaggtcat atccgcttct tcaatgtcgc gatccgcaac cgattcgagc agtggctgat
     9901 cagactcagc cattaccgac cgctggttga tagcattttc tctgaattcc agctgccgag
     9961 cgatctgatc tatctgtcat tggtagaaag cggtttcaat ccccacgcct attcacgtgc
    10021 ccgggctgcc ggcccctggc aattcatgaa aggcacggcc aaggtctatg ggttgcgagt
    10081 ggacagttat gtggatgagc gccgggatcc ggtgaagtcc accgtggcag ctgcgcgcta
    10141 cctgcgcgac ctgtacgatt tattcggcac ctggcccctg gcgatggccg cgtacaatgc
    10201 gggagagggc aaagtgatgc gggccttgca cacggcccaa gcagaaagct tttcggacat
    10261 tgcgaaaacc cggctcatcc ggcgggaaac gaaagaatac gtgcctcggt ttatggccgc
    10321 gaccatcatc gctaagaatc cggaccggta tggcttcccc caaaacgatg tccgacctca
    10381 ccagttcgaa gaggtggtcg tgaggcgccc catccatttc aaagccatcg ccaatgtcac
    10441 ggggatttcc taccaggaac tgaaggtgct caacccggaa ttacggcgcg atgccacgcc
    10501 tccggatgac cccgaatatc atttgaaggt tcccgtaggc accagagaga aggtggaaca
    10561 gttattagaa cgggctccga ctcacaagtt tccgccgctg ccaatgccgg ttcaggtcaa
    10621 aggccgacat ttcaagaacg agactgattc tggacattgg tatcgcgtcc gcgtcggcga
    10681 ctcgctggag aaaatcgcca aacggtttaa catctcagtc aaaacgctca agtccaacaa
    10741 caacctgacc ggtcccacca ttaaggcagg aagccgcctg gtcatcgcca actaggtcga
    10801 cccgtctccc gctgtaaggg gaaagaccag gctactgctt tttcttggaa gacgaggcag
    10861 ccgacttgcc cgttgaagcc ttggcaggct gttcaggctg agaagcaggg gcgctggctg
    10921 ctggggccgg tgcgggagct gccgccgggg tttccggagc tttcttcact tccaacactt
    10981 tcacacgtac cgcagcttca ctggtgaagg gcgagttggg ataattcttc atcagatcct
    11041 ggtagtgtgc gagggctccc tccggacggg actgcgactc ttcaattttt gccaactcga
    11101 acaacacatg atccttgttg agggctccgg ggacgtcgag aatgcccgtg aaggccttca
    11161 ccgcctgatc gcgatcaccc ttggctaggt aggcataggc caaccgttgc tggaccaatc
    11221 ctaagagcga ggtgttggaa ccgtacaaca acatgaaccg tttgtaggtt tcgataccgg
    11281 catccacttc attcgccaaa acctgcgcat tccccaaatg gaacaaggcc aagggcgcag
    11341 cagggcttct cggatattgc tccaccactt gcttatagag cgcgatagcc tgggacagct
    11401 gttcctggct tttcttcggg tcgtctgcgg gccgattgag atagtgcagc gtggcttcct
    11461 gatcaagctc tcgcgctttt aatgtggatt gatagtcgta ccacatcaca ccggcgacga
    11521 ccgctccggc aaccaacacc acccccagcc ccgccaagac ggcgcgccgc tgttcctgca
    11581 atacatgaag aacccgatca acgccggtca acaggtgggc ttcgtcgagc gggtcaactt
    11641 ttgcaggaac cctgattcga taactcatgg tcgaacaatg gtctcggttg gaaaagacgg
    11701 tcgtttctca gagcctcgcg ccttatacta gggaccactc agccttgtca aatgtttggc
    11761 ctcgtcaaag cccgggcacc catgttcgaa aaacatctcc agaaactgga tgatcaacat
    11821 ctcttgcgcc ggcttcgcac gatcgcctcg gcgaccggac caacggtcac attggacggc
    11881 cgtgacatca ttctgctctc ctctaacaat tatctggggc tggccacgca tccaactgtg
    11941 gtgaatgctg ccatcgaggc aacccgccga tatggagccg gcgctggcgc ggcacgcctg
    12001 gtttgcggga cgctcacacc ccatgagacg cttgaacgca ccctcgccgg attcaaaggc
    12061 acagaagcag ccctcacctt tgccgccggg tacctggcca atatcagcgt gattccggcc
    12121 ctgatcggaa aagacgagct gatccttgcc gaccgtctct gtcacgccag tctcatcgac
    12181 gggtgccgtc tgagcggagc cacctttcgt gtgtaccatc atcgagacat gaatcatctg
    12241 gagcaactgc tcgcccgtcg tcccgccggt cgacgtacac taatcgtcac tgatgggcta
    12301 ttcagtatgg acggagacat tgccccgatg aaggatctcg tacagctggc ggaacggtat
    12361 ggtgcagagc tctatgtcga cgacgcgcat ggcacaggaa ttcttggacg caccgggcgc
    12421 ggcaccctcg aacattgtga ggtcgaatcg cgtgtgccct atcacatggg gaccttgagc
    12481 aaagcactcg ggagcgcggg gggatacgtg accggttcag ccacattcat cgcctatttg
    12541 gtcaacacct gccgcgcgtt catttacacc accgctccgc ctccggccac tgccgctgcg
    12601 gcgaccgctg caatccaggt gatcgagcag gaacctcagc ggcgcgccag cctgtggcgc
    12661 aaccgcgaac gactggcaca aggtctcctt cggctgggat tccgcctcgc ggcatcggag
    12721 agtccgatcc tgccggtgat tatcggcgat cccgatcgtg cgatgaagtt agcgcaggcc
    12781 ctccttgcac aaggcgtgta tgcccccgcc attcgtcctc cgaccgtgcc tcctgctacc
    12841 agtagaattc gcttcaccat cacggcggac cataccgatg agcagatcga tcgcgcactg
    12901 attgctgcag aacaggccgg tcgatccatc aatctgatct gacctgacga ctccccagtc
    12961 atctcccgat gaccacaaga gttagggccc tagcaacggg catttcgtcg tcgcctcttc
    13021 tggatatttt cttgatttct caccctccta tggcatgatc gaaatggtcg agcgagcctt
    13081 gatcttctag acataactac gttcgtttta tccgcgcaca ttctctttca atggagcgac
    13141 ccgatgattg acatctccaa actgttgacc tttggtgtcc agcaaggtgc ctcggactgt
    13201 cacatcagcg ccggcgaacc gccgatgatc cgtctgcatg gtgacctcaa aaagctcgac
    13261 catccacccc tgacacagga tgaaactcac gccctcatct acgacatgat gagcgatgcc
    13321 cagcgcaaaa actttgaaga acatcgggaa tgtgactttt ccttcgacct cggcgacatc
    13381 gctcgattcc gcgtgaacgt ctttgtccag ggccgcgggt taggtgctgt cttccggacc
    13441 attccaacgg aaattcttcc gctcgaaaaa ctcggcatgc cgcccattct ccgacaactg
    13501 tgcgaccgtg agaagggcct gattcttgtc accggcccca ccggatccgg gaaatccacc
    13561 accctcgccg gtatgatcga ctatctgaac aacacctttg aaggccacat tctcaccatc
    13621 gaagacccgg tggagtttgt gcacaaatcg aaaaagtgcc tggtgaacca acgcgaatta
    13681 ggcgtacaca ccctgtcatt cgccaatgca ctccgtgccg cactccgcga ggaccccgat
    13741 atcatcctcg tcggcgaaat gcgggacctg gatacgatcc agttggcgtt gaccgctgcc
    13801 gaaaccgggc acttagtctt tgcgactctg cacacgtcta gcgccccgaa aaccatcgat
    13861 cgcatcatcg atgcgtttcc tccgaaccag caagcgcaag tccgcgcgca gctgtcggaa
    13921 accttggaag cggtgctaac acagacgctg ctcaaaaaga aaagtggtgg ccggattgca
    13981 gccgtggaaa tcatggtcgg caccactgcg gtgcgtaacc tgatccgcga aggtaagctg
    14041 catcaaattc ccggcatcat gcaggcgagc cagaaagacg gcatgcagac catggacatg
    14101 gccctggtcg acctcgccac gcgcgggatg gtgaccaaag ccgaggccca gtctcgcagc
    14161 atgaatccca acctttttaa cacggccggc gcggcctaac gccccattca cggtattcgt
    14221 ctaccgatag ccgcataaga ggcatctcat ggatgttcgc acactcctcg aagtgatggt
    14281 caaacaggaa tcgtccgacc tgtatctcac cgtcgatgcg ccaccgattt atcgcatcca
    14341 tggctcgact catcgaacag atgcgccacc gtttaccaat gaacagttgg agtcattggc
    14401 actggctctg atgcgcggcc agcagcgtgg cgaattcgaa gagaaaatgg agatgaacct
    14461 cgccctgtat tacaaagacc tcgggcggtt ccgcgtgaac atcttccggc aaaagggaaa
    14521 cgtagggtta gtgtttcgtc acatcaaggc ggagatcatg acggttgagc agttggacct
    14581 gccgcccatc gtcaaagata tcgccatgac gaaacgcggg ctggtccttg ttgtaggggc
    14641 caccggctcc ggtaaatcca cctcactcgc ggcgatgatc gatcacagga acaccgtgca
    14701 tgcggggcac attatcagcg tggaagatcc gattgagttc gtccatcacc acaaaaaatc
    14761 gatcgtcacc caacgggaag tcggtttcga cacgcattcg ttcggcaatg cactgaagaa
    14821 cacgttgcgc caggccccgg atgtgattct catcggcgaa attcgtgaca cggaaaccat
    14881 ggaagcggcc atcacctttg cggaaaccgg ccacctctgc ctcgggacgc tgcactcgaa
    14941 caatgccaat caatccatcg aacgcatcat gaactttttc ccggtggagc ggcacgccca
    15001 gatttacctc cagctttcac tcaatctgcg ggccattatc tcgcaacgcc tcatcccgtc
    15061 actcgatggc cgacgggtac ctgccttaga aatcatgctc gatacgcctc gcatcaaaga
    15121 tctgatcaag cgatcagaaa ttgatacgtt aaaagaagcg atggaacaag gtattgatga
    15181 agggtgccag acctttgacc atgtgctctt acaactctat aaggccggga aaatcagcat
    15241 tgaacaagcc ttgatcaacg ctgatagcgc caacaatctc cggctcaaga ttaaactggc
    15301 gggattaaaa ggtgatgatg cagtggcagc cctgctcgac aaaaacgaaa gagatgaaaa
    15361 gggcttccaa atccagggac agatgagcca agggggcggc aagaaacgat gatgacggac
    15421 aggagtgagc tactgctcta ggcctcacgc aagcaaccag gtgtatgaag cccaggctac
    15481 ggctcatccg tagcgagttc gagatacgcg gcgatcttat ccagcgctcc tgcagtcaat
    15541 ttcctcccat accagaccgg catcgtgtcc gcaggaaaac caggcaccac ataggtgcct
    15601 ggcgacacca ctgactcaac aatatattcg cgaaccgttt gcgcctgccc ccgatattgt
    15661 ggatctgcca ggcgagaggc accggtcttg cccagccaga gcggagggcc gacctttcca
    15721 tcagccccca cgatacccgg aatccgatgg caaaccacac aaccggcgcg aacaaagagc
    15781 tcttgaatag gctcctcccc cgtcaccaac ggcaccatat tcgggtctat gttcggaaca
    15841 gccggagcca ctgcggacgg tggcggagca ttttgaattc ccaccagagc cagcaacaac
    15901 accaagccgg cgaccaatgc cgcaatcgct ttatggttat gctgtgaggg cggaacagag
    15961 gaagaatcgt ttggagcgac catacaccgg caccatgaac cttacacgca cattgaacaa
    16021 acacgctact gcgtcaacag atgaagaaag actactagtc tcggcaacgc gtgaataata
    16081 gccgatgcta tagtcccgga gtcatggcgc aacgaaagcc gatcgctcga tcctgaaaat
    16141 ccggttccgc cgagactcgc gcagatgatc gtaacgccac cggcagatct gaccaggacc
    16201 ctccacgaat cactttcttc tctccggttt ccgggccagt gggattcttt tcaggactct
    16261 tcgaatagta ttcccgatcg taccaatccg ccacccattc ggcggcattc cctgccatgt
    16321 ggtgaaggcc atagggactg cgcccgcctt ctttcaagcc atggcgtaca ctcatcccct
    16381 cgacaccgcc actcactgag gtaagcgtca ccgcctcgct cacccatacc ccgcgattgt
    16441 aattcgcaat gtcgacgaag ggctgcattt gtccccacgg gtatcgccgc ccgtcggtac
    16501 cgcgcgccgc cttttcccat tcggcctctg tcggaagacg ctttcctgcc caggcacaat
    16561 aggcctttgc atcagcccag cccattccta cggccggacg atcaccaacc gtctctgcgg
    16621 cttcatcatc ccaggtcgga ggagcatcgt gcttcgcctc tacgaggaac gaccgatagt
    16681 gcttcatgga gacttcatag cgatcgatat aaaacgcgtc gagagtcacg gtatgttccg
    16741 gtcgttcagc gggaagcccg tcgttactgc ccatcgtaaa tggcccggcc ggaatcagca
    16801 ccatgggcgc gccatctttg cctttgatac cttccgcaga agtaccgctt gccgcggcct
    16861 gaggttcggc agccgaggcc atccctacgc caacaagcat gatggctgac aacacggccg
    16921 ttacactgaa gagtcgcata cattcctccc atctgcgata gatccagagg caggtcacca
    16981 cgcccggcaa agtgtagccg tgcgggcagc caaactcaac tgcggcaaaa tccgagacac
    17041 ggttgaaagt gatgtcgctg tcggcaaggt gagatagtgg ttgggaaaag cgagtcccgg
    17101 agaaaggcga tacaaccggc ggcggcatgt tggccggcaa gaaggtcctt gccggcctgg
    17161 tgggaaagag gaaggagtgg cgggatagtt accgggcgag ctctgcaaca cggcggtcgt
    17221 gatcttttac cggcctcgcc gtagccactt cagaccggtc taagaggttg tggaggactt
    17281 cttgtttcaa ctgaaccata agcgccttgt tatggtctga ggatagcgat gcatcctgaa
    17341 gcagattgag ccagcccacc gtcgcaacct cataccggct gttcggcatg gccgtgcgta
    17401 attcctgaaa caccgtaatg gcatccgccc gattttcaaa caacgccacc aacgctcgcg
    17461 tgtagtaggc atcttcacag gctgggccct tatggcaatt cttcattctc gcatcctgcg
    17521 catgagcaat ggcctgaagc ggcttgagct ccgaggcatc gagggggaaa aatgcgctac
    17581 tgggtaggac cgtggaggtg cccgatggca tcgttgtgca tccttcgacc acaccaacga
    17641 gcagcaggag aagggtgaag cagaaccctc ggtgtttcga catcgtaagc ctcctcaact
    17701 cgcgctcgcc agatgggggc gcgatgatat tgcgatgtac ttggcttgca gggatgttct
    17761 gaatgtacca tcgcgcttcg gttcagccat tacacggagg ctgtacctct ttggtatggt
    17821 gaatctgcgc ggggcacggc caggtcacag gcactcattc gaacgaaata agtggggatc
    17881 gggcctgaac aatctcagga ggaggaagac aacggtgata agaatcctcc gccccgcctt
    17941 gtatgcgggg cgaaggctcg gccttaatgc cagtttgcgg caagaatttg ttgcacgtcc
    18001 tgtgggcgct gagcaatggc ctgatcccaa ctgagcccag tctgttgggt aaatcccgcc
    18061 atagcctgaa tgagttgatt cacctgagta ctcatcaatt gttgaccatt gcctgcttgg
    18121 accgtttcaa tctggttggc tgcaccggca taccagttgg taatggtcac ctgatcggtc
    18181 gaaccataga cggcaatgcg caaatcatta gcgctctgac tcaacataag atctagtgga
    18241 ttgatccccg acgcaaaact caagcgatcg ctgctcccgc tggcatctgt aatcgtgtct
    18301 tggccatctc cgcgagccac ctgaaacagg tcgttccctg tcccaccatt gagcacatca
    18361 tttccttttc cgcccgacaa cgtatcattg ccgtcgccac ccatcaaaac gttgttgccg
    18421 gcgttaccga tcagagaatt agctagagta ttgcctgttc cgttgatcgc ggctgctccg
    18481 ctaagagtaa ggttctcaag attcgcacct aaggtccagg tcaccgtgct ttgcaccgta
    18541 tcaaggccag cgttcaaagc ctcgaccact gtgtcgcccg tccctaccac atacgtgtca
    18601 tccccggcgc cgccggtcag ggtgttggtg gcattattgc cgacgagaat attattaagc
    18661 gcgttacctg taccgttgat cgcaccggtg cctatgaggg tgagattttc gacattggct
    18721 gcgagcgtat gagtcacgga actctgaaca gtatcgatcc cggcatttat tccctcgacg
    18781 acggtatcac ccgagccgat gacatacgtg tcatttcccg cacctccgac taactgattg
    18841 gcagcactat tcccaattat cacgttgtcc agtccgttgc cggtcccgtt gattgcggag
    18901 gtgccgctca gcgtaagatt ttccacattg gcactcaacg tgtaggtcac agaactctga
    18961 accgtatcaa gcccttcacc ggctagttca gtgatcttgt cgccgacgtt gtccacaatg
    19021 taaagatcat ccccctgagc cccgatgagt gtatctgccc cagccaggcc actcagaata
    19081 ttggccgcac tgttaccggt cagggtgttg gcgaggctat tgccggtccc gttaaccgca
    19141 gcaatgccgg tcaagatgag attttcgaga ttcgtgccca gcgtccaact gatatcagac
    19201 ctgacagtgt cagtacccgc actcgccgcc tctacaacgg tgtcgccaag gcccaccacg
    19261 taggtgtcgt ttccggcccc accagtcagg acatttgccg cactatttcc agtcaaaata
    19321 ttattcagag aattgccagt accattgatg gcagcgcttc cggtgagggt cagattttcc
    19381 aggttcgaac ccagcgtata ggttaggcta ctgtacaccg tatcgatacc ttgaccgact
    19441 gattccatca cgatgtcgtt gatattgtcg accataaaca catcatttcc ggaaccaccg
    19501 gtcatgcgat ctgcgccagt gcctccatca agcgtgtcat tgcctgcgcc tcctgagagc
    19561 acgtcgtcgc cacctacccc caacaatgta tcgttcgtca catttccgta aaaatagtcc
    19621 gtgtcttcgg tgcctaccag attgacgcct tccgtatggg ccaacatggc gctgtaatcc
    19681 cacatcgtcc catcgctaaa ctgaattcga tcaacgcgca tcccatcgga ctggaaaaat
    19741 ccagcgagcg tcacttgatc cgcactattc ttgatggtga gaagagcgtc ggtttgaaaa
    19801 tcaggcgttg cctgcaaggt gatatcgccc ggtgtaattc cgtcgacaag ttgaagggta
    19861 tcgatatcag cgctgtcacc ttgatcatca atagtatcgt gcccataacc gcggccgaac
    19921 acataggtgt cgtttccgct atatccttcc aggaagtcgt ttccgacgcc tccgtcaagc
    19981 acatcattcc cagcattggc tcggatctga tcattccccc ccatgcctcg gatcgtatcg
    20041 tcaccagctg aaccatagaa tgattcgtca gccccgacgc cgatgaaggt tcgtacgcga
    20101 ttttcaatct ctccagaggt ccagatggct ccatccgcga agaggaattg atctaccatg
    20161 ttcgctggag actcgtaata agactgtacg cgtaactcgt cggcagttcc ggtaaccttc
    20221 acgacgagat cgtttgcctg tctttcgaga ctgagattgg agggggtcac accctggagg
    20281 aattgtacct gatcgagccc cgaatgggca tacacttgta gccccgtcct caccacgtcc
    20341 tgcccgtacc cagggccgaa cacgaaggta ttgtcgccgg tcccaatcaa cgtatcattg
    20401 cctgcttggc cgtccaaccg gtgggagccg gacaactcat tgtccaaagc attcccaacc
    20461 aaattcacct ggaccgtaga atcgaggtac acatcatcct cgatcctcac attctcgaaa
    20521 ttgtccggcg cctgaaatgt aagcgattcg gtcggagtga ggtaaatcgt gtcccggcct
    20581 gcattcactt cctcggtgat gacttggccc atagagcgga gatgatatgc atcatctcct
    20641 ccaccaccaa gcagctggtc tcccaaaccc accgattcca aaatgtcatt gccctcgcca
    20701 ccgcgcaaga cgttgaatcc ttggttccca tagagtcggt cgtttccggc gccaccatct
    20761 agttcatcat caccttcatc accttgcaag acatcatcgc ccacaccacc gagtaacaca
    20821 tcattgccac cacgcccata caataaatcc ccaacttggc tgccttgcat acgatcgtca
    20881 aaactcgttc cttgtagcgt cccaccggtt tccggagagg acagctgaaa ccctcgggcg
    20941 agcaactcgc catccgtcaa cactgtgccg tcagcaaatt caaactgtcg gatagtatga
    21001 aactcggcgg gatcgttcag tccaaaattg ctgacccgaa tcacatcttc atcattgccc
    21061 acgcgcagaa ccagcgtatc tgctggtccg acatccaaac gtagcgattc ggcagtgatg
    21121 cctgcgccaa agatgagtcg atttctttgc acaccatcat cttggatcgt atcggcacca
    21181 tcacccaggt taaagcggta cgtgtcgagt ccgcttccgc caatcagaag gtcgtttccc
    21241 ctacctccct ggagatcatc ctcgccgcct ccgccctgaa gcgtatcgtc gccctcacct
    21301 ccatccagca catccgatcc tgcttgtgtg gagaagaacg gggaatctcc gaataggaaa
    21361 tcattgccgg cttcaccata gagctgatcg tccccagcat ctccaaccag ctgatctgat
    21421 ccctctccgc caaacaattg gtcctgtccc gccccggccc aaagctggtc atcgccctct
    21481 tccccatcca acgtatcgtt tccacctgca agactcagaa cagtaggatt gttcccatcc
    21541 ccgtatagaa aatcactgcc gtcaccgccg accaaaaaat catctccttc acgtccttgc
    21601 acatcatcga tgccatcgcc accgtccagc tggtcattgc cgagtccgcc attcagcaaa
    21661 tcatcgccgg cttctcctga aagaagatca tctccatctt gaccaaacag cgcatcatga
    21721 ccttccccac cgaaaagagt atcgcctccc gcatctcctt gcagttcgtc gtccccttcg
    21781 tcaccaaaga gcgtatcgtc tccctcctgc cctgtcacac ggtcatttcc aagcccgccc
    21841 cataaagaat cgtcccctgc gcctccctgc aactcatcat tatcagcgcc gccatcgagg
    21901 aaatcattcc cgccaaatcc ggcgagccga tccataccga ttccaccata gagaatgtcg
    21961 tcgcccccgc ctccctgaag ctcgtctgct cctgcgccac cgtcaagaat atccgctgac
    22021 ccagggtcgc cggagaaatc accgactaag aggtcatccc catcacctcc agagagcatg
    22081 tccgctccgg ctcctccgaa gagcgaatcg tttccctcac ccccatcaag ccaatcatca
    22141 cctgctatcg ttagagtgaa atctgactcg ccatataaac gatcgtcacc ggctccgccg
    22201 agcagaatgt catccccgcc atcgccgacc agcaagtcac tgccggcccc tccgtctaga
    22261 tagtcgttgc cgccagacaa cgaaatgatc cctgcttggg gggttcgatt ccaaaaagag
    22321 ttgtcgtacg ccagtccaat ccaacccgta ggacgatttt cgccacgaag cacatcatcg
    22381 ccgtcaccgc ccaacagcac atccgccccc atctccccca tcaacgtgtc gttacccgca
    22441 ccgccatcgg catagtgcgc cccaccgcca atgatcggtt ccgcaaaact caaatagttt
    22501 gctgttccga cagcataatc atctccatcg ccaccaagaa acatatcccc atcggtcacg
    22561 aaggcataat cgtcaccata tccgccgatc aaataatcgt ccccgtatcc gccaaagaac
    22621 acgtcattac cagcaccgcc atccaacaga tcatcgaacg cgccaaggat cggcgcatgg
    22681 tctccgtgaa gaacatcatt gccaccgttg gcataaacct ctatcgcccc tgctccagga
    22741 acccactctt ccgcgtccgc gccgcctata taggtgtcag taaaatgtcc tgccggaact
    22801 ccggtgtcgc gcggcatcgc cgacacgtcc cgcaactgaa tccccatctg accgctttgg
    22861 aaattctcgt taacaatgag aaccccgttg acgatcagat cggtccctga catgacatag
    22921 gtagtttggc cgtccaggct tgtataggtg ttagtgccat cgcctgcacg gcggatacca
    22981 ccctgcagca ggcgggcgtc aaaaacaatc tgcccctgcg cgtcgctgtc ttcgatccga
    23041 tccattccgt caccggaatg atagatatag gtgtcgaatc ctatgccgcc ttctaagagg
    23101 tcgttatcgc cggtgccgcc aaggaggatg tcgtttccgc cgccccctac aagatgatcc
    23161 tgccctccga gcccgctcag aatgtttatt gcgctgtttc caacgatcgt gttctcgagt
    23221 tcattgccgg ttccattcct agcgcttgac tcggtaatcg tgaggttttc gacttgggag
    23281 tcgagggtga acgtgacgga gcttttgacc tcatccctgc cactattcgc atactcccga
    23341 accacatcgc cgatgttatc gactatatag atatcgtctc ccgtcccacc cagcatcgta
    23401 tcagcaccgc ttccaccatc aaggagatca tcctcttgat ttccttccag ataatcttta
    23461 ccaccattcc catagagctg gtccttgcct tggccaccgt atagatgatc tacaaaaagg
    23521 agactcccaa taagtgaatc gcctccctgt ccgccaaaca gtacctgggg caagggaaga
    23581 gcgtcagaac ccagctcata ccccaactca atatcattaa aatgtgttag ggatgggaga
    23641 ctgatagaat ggctgtccac ctcgatcttt ttcagcaaaa acgccgcccg atcctcgaaa
    23701 tacagcgatg taaggtttcc cgtaccggtg ttcggatcca acagcgaaag ttcacccgtc
    23761 tcattgtggc ggctgtagag cgcttgcgtt gtatctcgat ccattcctcg caacacgaag
    23821 gggttgagtt ccttcagcgc atatcggtac gcaagcccta aggcatcgtt cggaccatct
    23881 tgtagggcaa tcgtcctcat tgtgctggca gactggccaa ccaaagagtc aatccgataa
    23941 ctgacaccag taagcgcggc agtgacttgc tgaatgtttt gatagaaggc atccctgttt
    24001 ccgagattgc caaagtcgcc aggttgccga ccaaaggggg tacttgaaac gtttccaaga
    24061 aagactttgc gaagtgcatc taacgttttc tccagggtgt caccttcggc tagtggaatg
    24121 acacctggca acactgtcac atcggctttc tgcgccgaaa cagcattgaa aatcccctca
    24181 atttgtgact gctcaagagt aggatcaacc ttcaggaata gctcttgaag ggcaaaggaa
    24241 tccacaagaa gagtgagact atgcgtattc ccatactgaa actctctctg ctgattgaac
    24301 ccctcaagca gaggttgtcc ctcaataaat atactttggg aaggggcatg gatccctgag
    24361 ttggccacaa actgcacgtc actgccggtc tcagcattcc cgactaactg aacaacctta
    24421 tctaacgctt cactctgcgt cgggataccg cccactactc cggcaggaat tgtaaagaat
    24481 tgagtattcc ccgtgcctat tgttggaaat cgggtcagag tggcctgacg agcgacatca
    24541 tagcgagcat cgccatagat gtttcctgct gccccactcc tgaactgtgt tccctctggg
    24601 tcaaatgcga gcagacgccc ctcaagatcc aacatcatcc gacgaagagt ttgctcgacc
    24661 ggctgcccgt cctgacccag ttcggacacg aaaccgcgtc cagcgccatt gaaggtgtag
    24721 gtttgcagaa tgcgatccga atgcatctcg gtgaagacgg ttgccagatg gccgcttaaa
    24781 gaataaccgg tcacgttgat cttggcgtca ggagctaatt tgcctccaac agcagttagc
    24841 tcacgccagt aacgctccat actcaccagc tgagccaaag caaaaccata gtccttaatc
    24901 tcgccatcgg cccccggcag gccgtcccgc tgccaatctc caccttgggc ctcatcacga
    24961 tactcggtac ttcggatgga aagagtatat tgttgcgttt ctttatcgaa tagaagcgtg
    25021 gcactaaatc cagtcgcgtc actggcgtga tggtcgacaa tgtcgtatcg agcaagaaat
    25081 cgatctgcta atacgcttgt gaaccgagtt tttccggcaa gatcagcgtc cgttggactg
    25141 atcccaaatt ggttattgtt gcccagtaat aaacgtggtt tcaccaagag ttcattgtgc
    25201 agatcaatat cttgaagata ggactccgca gccatttgct ggagagcaaa attgagccat
    25261 gccgtcgtgt tacttgacat tcattaactc cctaacattc atctcataat tgatcggctt
    25321 aacaaccttt ccgataaacc aataagaaaa atcaaaatct ctactgcgcc cacctctgtg
    25381 ttgatagtag ggacaagctt gaccggtgag ccaccacact cctgtgaggt tgttacgaac
    25441 gctcccagtt cgaatatatc cacgccttac ccctaagacc tctccggtct ccatgtccaa
    25501 tacaataagt tcgccaccag caattcccat ttctcgatcg tgaggacgaa cgatacctcg
    25561 ccatgtatac ccatatctcg ccttcctcac tgaatcgaac tccttgatca tggttagtgg
    25621 atctttccca ttcgatccta gatatcgttc atgatacgcc cgatcgctcg gggccgtgaa
    25681 atacgaattg tctagaaatg attttcccca gctaggcttc ttccttgggg ccagagggtg
    25741 ttcaaagaat ttataacgaa gcggcccaac gaaaaagaat tccggatcct gagattccgc
    25801 atccatatac ccatatggat cttccatggc atacagatgc tcttgcatgt aatcattcgc
    25861 gtgctcacgc ggccgcatca tgtagagtcc ctcaacgttc tcagctgttt tgtaaataaa
    25921 ctctccggct tccgtcttac aaagatgctc aaaatactct tggctcgtca tccctggctt
    25981 atatccgctg tcttccggca caggattcgg gatcttgatc gaatgagcaa accgtccctc
    26041 ttcggtcgcc aacggatctg ctggcttgag cttggctacc tctccacaca cttcccctcg
    26101 ggcgagcttc cggctttcac aactctgctt gattttctcg atggctttcc ggaaccgctc
    26161 ccctactgtc tcatcttttc cgaacagccc cgcgccggtg ggggcaatca acgccagcga
    26221 caacaggccg gcaatcacga ataggcttaa cattcgtctg ttttgcttca tgagaaaccc
    26281 tcttcctgaa ggttcatgca ccattatttg tgcatggatt tgcctaccgc tcccgcaaac
    26341 tctctttcat cgacttcaat aacgggctca gcaaaaactc gatcacccgc cgctgtccag
    26401 tcttaatctc caccgtgaca gccatgccgg gggtgagatg aacgtgcttc ccctctacct
    26461 gcatcgtggc tcgatccata ctcacccggc tcacatagac cagaccgcct ttttctttat
    26521 ctaacggtac cgcatcgtcg gagacggtca acacctttcc gggaatcgtc ccgtacaacg
    26581 taaacggaaa cgtttcgatc ttgagttcca ccggctggcc ttccttcaca aatccaatgt
    26641 ctttattttc gagctgcgct tccacttcga ccgggtggtc ctgcggcaca accatcagca
    26701 gagtttgagc cggcgtcact actccgccta ctgtgtgcac ggccaattgc tgaacaacac
    26761 catctatggg agaaaccaga ctttgaagtt cagttttttg tccggctttc cgcacctctt
    26821 gtacaagtga cgtggctttc gtctccatgg ccgacagttc tgcttgctta ctttgctgaa
    26881 attcagaaat gagcacctga tagttctgct ctgcctcggc caaggccgct tgatcctgac
    26941 gtagcttgct cttttgccct gcccattcct gagctttatc gatgcgttgt tgctcgaatt
    27001 ggagatagtc catcttcgac acatactgtt gtgccagcaa tgcccggtaa gccgctgccc
    27061 tttcattttc catcggaacg gtggcttcga gacgtcggag attgtctttg gccgcatcta
    27121 cagccgcttt acgctgcccg atgagatgtc gtgcagcatc tacccgggcg gcatactcga
    27181 ccatctgatc ccgtaaaagc tgctgttgca gcaacacaaa ttccgggtct gactcactgg
    27241 gcgcggtgaa cgtactgtgc ccggctatca gcgcatgcag ccgagccgcc tcgaccagag
    27301 ccgctcgata ttcattggaa gcccgatcac ggtctgcgct gttttgagtc gcgtcaagct
    27361 caatcagaac ttctcctcgt ttgaccgatt ggccgtcctg cacatgaatc gcagcaatca
    27421 cacctgtctc gaacggttga atggttttag aatagccgct gggaataatt ttgcccggcg
    27481 ccaccgccac gatatcgacc tggctcaacg aagaccatgt cacggctgag gcgaaggcca
    27541 gcatgatggt ccagagaatc gcccggccaa tcggcgacgg cggtgcatcc tgaatttcaa
    27601 gaattgcggg cagaaattcg atcgcttctc cttgggctgc ggcgtgagat gactgaccgg
    27661 aaccaacgcg cccgattgtt cgccatcctg ccagcttgag ttgaagggca ttcatcatta
    27721 cgccgcacgt ccttgctgat gctgatgaag tcgcgtatac atcccgtcgc gcgagagcaa
    27781 ttcatcatgc gtgccctgct caaccaattg ccctcgatca atgacgtaaa tcttgtgagc
    27841 aggacgaacc gtgctgagcc gatgcgcgat gatgatgacc gtacgccctt tgcagatctg
    27901 ggccatattg cgctgaatga tcgcttcgga ctcatagtcc aaggcactcg tcgcttcatc
    27961 gaagatgagg atgcgcgggt tcgccaccaa tgcgcgtgcg atcgcaatgc gctgccgctg
    28021 tccgccggag agcgcgcagc catgctcccc gacgaccgtg tcgtatccat ccgtcaactc
    28081 aagaatgaac tcatgagcac cagccagttt ggcagcatgc atgacacggt ccatgggaag
    28141 cccaggatcg gtcaacgcga tgttatcccg cactgaccgg ttgaagagaa agttctcttg
    28201 cagcaccaca ccgacttgac gccgcaacca ggcagggtcg atctgcgcga gatcaacacc
    28261 gtccaccaga acccggccac gctctggcac atagaggcgt tgcatcagct tggcaatcgt
    28321 gctttttcca gatcctgagc gccccaccac accgacgacc tgccctggat gcagagtaag
    28381 agaaacacgc tgcagcacca acggcccatc gacacgatac cggaacgcca catcgtcaaa
    28441 tacaatctgc ccggcaatct gcggaagagt cgtgcggttg ggattgtagg acggttctag
    28501 cttggcattg aggacatccc ccagtcgttg tatcgagatg ccgacttgtt gaaattcctg
    28561 ccagaggttc accatacgca gtaatgggcc ggttacttgt cctgagagca tgttgaaggc
    28621 gatcaactct ccgatgctta aggcgccgtc gatgacctga taagcgccca cccacatgat
    28681 ggcaatggtc gtagatttct gaatgcaagt cgctatttgc ccagccacag taatgagact
    28741 agtggcccgg aaactggcgg cgacgtatcc ggctaattgc tcatcccatc gacgctggag
    28801 cggtggttcg acggcgagcg ccttcacggt ttgaataccg ctcaccgctt ccaccaggaa
    28861 ggattggttc tccgcgccgc gattgaattt ttcatggagt cgcgcgcgaa tcgctggcgt
    28921 aatgagcacg gagagcaacg cgtataaggg cagcgaggcc atcaccacca atgtgagtgt
    28981 ggggctatag atccacatca cgcccaaaaa cacgatggta aacaccacat ccaggactac
    29041 cgtcaccgag ttactggtga taaattggcg gatctgctcg agttcgcgta cccgcgccac
    29101 cgtatcgccg acccgtcggg cttcaaagta ggctagcggc agcgcgagaa gatggcgaaa
    29161 cagttgcgct cccagcccca catcaatccg gttggtcgta tgggcaaaca ggtacgtacg
    29221 tagccctcca agcagcgcat cgaagagggc gagcgccaac atgccaaccg ccataacatg
    29281 aagtgtcgtg aatcctttat ggacgagcac tttgtcgatg accacttgcg taaagagcgg
    29341 ggtcagcaac gcgaacactt ggaggaagaa cgaagccagt accacttcac ccaacagacg
    29401 tcgatacttg aggacggctg gaataaacca agtcatgtcg aagctgacat cttctactcg
    29461 caagcctgac cgtttggtaa aaagcaggag gctaccgctc cagcacgcga caaactcctc
    29521 cttggaaaga atatgcggcc gctctttcag aggatcctga aggagggcct tttctccctg
    29581 tactttggcc aggacgacgt aggtgccgtc agttcgctga gcaatcgccg gaagtggcgc
    29641 ccccgccagt tcaccccacg aactgctcac caaaccggcc ttgaggccga cgtgcttagc
    29701 cgcacgcacc aaggcgtttg tcgtcaacat atggccagat agtccaaatt gatgctgaat
    29761 ctggccgcta tcgataggca gatcgtgaaa ccgcgcaatt aacagcaggc acaacagtcc
    29821 ggtatccggc cgaggtggcg ccgttgaaca agactcgaga tgggaagttg gaacatccat
    29881 gacgggatag cgagtggcgc gttaggacag ttttgatttg gcgggctgca ggctggcgac
    29941 catctgctga agttgttggt gcaggcggat caacgcgtcg agcggcaatg ccactctaac
    30001 ggccctgctt cccacaagct gtttcggcat cgcctctccc ttttgtgcac gctgcgcgac
    30061 tgcaccgatc agactcggct cgagaaatcc aaaatcaatg taggccaatc cttgtgcgag
    30121 acttgcatgt gaatagttcg ccagaatcgg ctggtcggcc tctgtactcg attgaagacg
    30181 aacgttcacc gccactgctt tatcaccatt ctgcttggga ctgcttccaa cggccatgcg
    30241 cttctccttt aagcaaatga acgacatact ggaacgaata ccccgcatcc gcacgatggc
    30301 gatattagtc gaaggtccct gcgtggaata ttccccggac gatgggcgat gagaaaaact
    30361 ttggtagccc agagatgtac ttaggtcttt gaggtccttt aatgcgaggt ggacctagtg
    30421 gcaataccca agagtgccac agctggactt agtccaatct atttctacat ggaaatgcag
    30481 ggacatatga cgtgcggcgc cttgcaggtc gagaaggccg atccgtctat caattcttcc
    30541 ctctcctacg tcgtcagtgt agactgaaca atatttactt cttgcggagg aacgatgcag
    30601 aaagttctca tgcttcaggc cggatggcgc acgctgtgtc ctgtcacggc actatgctta
    30661 agcctgtccg cttgtgcggg agtgagcaca accgacacat tgccgaccgt ggcatccgtc
    30721 gatctcgctc gatatgccgg gacctggcat gagatcgcgc gcttgccgat gtggtttcag
    30781 cggcattgcg tggattcgaa agccacctac accgtgcgca acgatggcgc tatcggcgtg
    30841 cgcaatgaat gcgtcactga taccggtggg catgatgaag tcgaaggggt cgcaacagtg
    30901 gttgatccag gcacgaatac ccggctccgc gtggtgttcg acaatttctt cgcgcggctg
    30961 ttcggttcat cccgcgaagg caactattgg attctggcgc tggatgctga ttaccagacc
    31021 gccatggtag ggactccgga tcgccgatat ctgtggattt tgtcgcgctc gcgccaactc
    31081 gacgagactg cttacacccg cctggttgag caggccagac gattgagatt tcccgtctca
    31141 gagcttattc gtccccaccg atctgcggca acatcataga aacggtagct acgtctcatc
    31201 tcgtctcgtc tgatcgctag cctctcatat cactgcggcc ctctgctctc tacggtctct
    31261 gccacgaacc tcagccctca gtttcggact cgccttgcga cgcaacatga accacgacgg
    31321 tctcctccgt tggtttcact tgcgagccgt ggtgcgtggc gtacaccgca atgaaggccg
    31381 caccaaacag aaatacttgg gaggcatagt aggcccacag caacactaat actaaggaac
    31441 cggccgcacc atagaaggcc accagtgtgt tatgcgctag gtagacgacc agcagtttgc
    31501 ttccgagcaa gtagagtatt gccgtgatcc ctgcacccac ccacacatcc gaccacgcca
    31561 cctgagcctg ggggacccac ttgtagatca tggcaaacag cgtcgagaca acgccgaatg
    31621 acatcaagag cccaataccc tgaaccagtc ttcccggcat tcccgttgtt tccaatacga
    31681 actgaatggc gatgccggtc caggcgctga gtgtgaggga agccagcagg atgaaggcaa
    31741 tgccgaacag cccggacagt gatgcaaatc ggcgtttcag gcggtctccc atccttggag
    31801 gatgtttggg ttgaagtccc cagatacaat ctaatgcatc cctcagctga tccatgactt
    31861 tcagcgcgcc gatgacaaag acccccagcg cgactactcc gttcacgagg ggggaccctg
    31921 ccgatctcca ctgagcaatg atgcgaaaga gtccattcgc tgccgattct ccgatgagtt
    31981 ccccgatctg ccgctgaagg ccgccaacca ttgactcgtc gcccaccatg ctcacggaga
    32041 ccatgatcgt cagcacgacc aagggcacga tggtcaacgc cgtataaaag gcgagcgcgg
    32101 ccgcgaatcg cggtcctggc tcatcgctcc atttcgcaat ggtttgtgtc gcgagagact
    32161 tgagcagggc ccacatagac tcacgccctc ctcttccgcc gaagcctcat atctccacgt
    32221 tgggcacgat gcacatcagc ctgtggccca tctatcgata ggacacgcag agcatggaag
    32281 cggtggtggc atctgactca ggtcagaccg gcagcgaaga tgggattgcc accgccgttc
    32341 agcctgtcgg tttgtcatct ggtctgtgtg gcgtggtggg tcgttggaga gcttcagtgg
    32401 caatggcttc gatcttacaa caggcatcat aggcatggtc atgtcccagc atcgcgccat
    32461 tgcgtgccaa gtcaatgatg cgctgaaggg cgtcggcata tccctgcatc tcggaattca
    32521 agttggcgcg ggcagcagac gcaaggttct gggccttgtc catgagaagc ctctcactcc
    32581 acagagaagc caggccaagt ggatgagacg gggacactca atggctacac acgaataatt
    32641 ctcggagcca cgacagacct ttgaaagaca cacccaatgt cgaacgttgt gaggcagccg
    32701 ccgttccgaa acttcattca gagactactc agagacttgc gccctatcta taaaataaga
    32761 ggtttccccg aaacacgtgg tgggaacgta gcggaactcc cggtaatgca gcacaacgcg
    32821 ttttcccatt tggccgtcaa gtatcttcgc gacatcatcg tcccatacgc taaagttcca
    32881 cagaacggga gccacgccag gaaccgtcgt catcgccaac tcgccttcat acgttttaca
    32941 gacccaccct ttccgagaca gtttctgtaa gtaccctgtg cggtctccgt ccgaataatt
    33001 acagccgccc aggaccgcta tgcacaacac cagggagacg tatgtcggta ccttcatcat
    33061 ggatgatgca ttagagcatt ttcgaggcgg gacgatacct aggcgtcccc ctcgtcgacc
    33121 agtggaaaga ctcgccggac aagctcagga acatcccgcc gcgccagtgg cgcggagaaa
    33181 aatagaagag aataaagtta gccgaacgtc accgggcgga gcagttgtgc ggtaggatga
    33241 gtgaggacct atcatgagaa ggagacctat gattgccaca ctcgcgaccg cactgcttgt
    33301 cgttctggcc acggttccca acggacatgc cgtggctcaa tccagccagc gagatgtctt
    33361 tgatgaacgc gacacccgtg tatttaaggc agtggggtgc acacaagata agcaaccagc
    33421 cgaagcgctg tactatatcg tcgcgagtcg gtcagatcta tcggcaggcg ttccgtctcc
    33481 atcagcgcaa ttcatgaaag acgaggttga acagaattgg caacggatcg cctcacagtt
    33541 gacgatggag caagtgaccg aagagcgttt taccgatacg tatcacgcgc tgttgaatga
    33601 catgattccc cgtttacagc gggccgtgga agagaagagt ggtgtatcca ttgcggtctc
    33661 ggaggtgaat agcaggccga tggatcgtac aaaagaccag gacgtcccga cctgcagttc
    33721 acagtaacgg cagtccacca aaccacccaa ccatcgcctc ccgatcccat cgtggccgaa
    33781 gagcaggcaa ctcggtactg ctcatctacg cacttcgtgc cgagatccac gtaataaaac
    33841 gccgctccgc tccactgtgg cctctccagc cgccgattca gaccggcttg agcatcgctt
    33901 gcggccccag cctctccgac ctggggttat tccttgggtc ctcgttgtcc tcttcagtgc
    33961 taacgtgaat gagtaacctt acacgaggtg ccatatgagt acgatcttat tgatcatcct
    34021 tattctcttg ctgataggcg cgcttccgtc ctggccgtat agtagcggat ggggctatta
    34081 cccctccggc gggatcggtc tcatcctgct catcgtgctc attttggcat taaccggaag
    34141 agtctagacg cgcccccttt gacggatcct ttcgcgagga cgcgcggcgt tcaacgacga
    34201 acttgtatcc ttaaagaaga acggccgtct ggatgaggca gtatctttta tcgtcactgc
    34261 acggatggcc gatcaagttc atcggataat aaggacggga gttccaccgc cagcggatct
    34321 tccagttcga tcggttcgta atggacggct acaatggaag tgagcggaca ggaaagccat
    34381 ccactcatgc cgcgcgtttt gaaacgaatg cccatcggcg gaagggcctc aagatcgacg
    34441 ctggcaatgg tgataccctc gcggtcagtc cattgaaatg tatccatcgt cagtgatcca
    34501 ggtatcacct cataccagga accatctcgg agaaggacgc gagcgactgt cgtgacatca
    34561 atcttcaggc tcatggctcc tccctcgtcg tcgccccctt gacggcctct ttcttgcccc
    34621 aggagacgtt cggggtgtgg cgtcacctcg atcgccttgt cctttgttaa ccaccgttgt
    34681 ggcctttcgc cgtcgatcct ggctcaatca actcgcgcct ggcagtgtgg tgtggcataa
    34741 gggccgccct ttattggcag ggtaaagcct aatgacgctg atgcatgcta ggtattcccc
    34801 tattggatcc agaagacaca aaggaaggca ggtagacggt catctcaaaa cccacaagaa
    34861 cgatcgcaac aaaaaagcgc acagctcctc tagatcgagg aacctgtgcg cttaccccaa
    34921 gcagggcttc ccgttatcgc tcaagaggcc gcgtgttcgc gcaacccgct ctggttctcg
    34981 atgttattcg ctacctgcag aaaccccgtt acacacgaag gtcttcctac tttagacgct
    35041 tccggggagt gcccggctta tcgacggcct tccctcagca cgtcttccaa atgctgccgc
    35101 aacgtaccga gctctttgga tttaaacgag cttttcgtgt gctccatgac ttggatagcc
    35161 tcttcaattg ccgcttcgta ccggtccaat cgagggcatt tcatcactgc gcagatatcg
    35221 gtcggggcct gtggttgacc cgttcgagac gcctccagag tgcggccgac cagcgccgat
    35281 aactggctga tatgccccat cgcctgagcc atatactcct gcgccgtcca ttccacctgc
    35341 tgccccctcc ctccgaactc gttcatcgaa cgtcccaggc gctcaaaaat cccagccatc
    35401 tttgcggttt cgtgcatggc atcctgtacg gcccgcgcaa tgctccttcg acggaggcct
    35461 cgatctacgg ctttcttgag ctcattcaaa tcaaccggtt tgatcaaata gtccacgatc
    35521 gacagtcgaa atgattcaat cactgttccc acggacgggt atcccgtcac caccaccaca
    35581 ggaaggtcag gatgtcgcct ggcgacagtt tcaagaaatt ccagttgcga gtttcccggc
    35641 atccggacat cagccaggag cagatcatat ccgttttcga ggagccgctc ggcctcaatg
    35701 gcatcccggg cggcattgca ggcgtaccct gcgtcggcga gtatggctac ggtcgattct
    35761 cgaaacgtct cctcatcatc agcaatgaga atgcgttttg gcgtaatcgt catcttcctg
    35821 ctcctttttc aacgcggctc ctgtgccctg ctgcccgaca ccatctgtga cattcagagg
    35881 atgtatcacc gtaaatgttg atccgcccgc cggccgcgta tggacctcga tcctgccacc
    35941 catggctcgg acaagcccgc gggacacaga gagtcccagt ccgagcccct gcggaccgcc
    36001 ggccgatttc gtcgtaaaaa atggttcaaa aatatgcgga aatacctcgg gggtaatgcc
    36061 cggcccatga tccatcacgc tccaatggag cgtgtcaccg tgccgggcca ccttcaacac
    36121 cacttccata tcctggggag acgcatcgat ggcgttctgc acgagattga gcaatacctg
    36181 aaacagatcg gcgcgcggca gggtcaccac cggacaggtc aactctattt ctgtgcgtaa
    36241 ctggattcgg cgcgagacca gcttgtagtc cagcaacgtt cccacatttt ggagcaggtc
    36301 gctcacgtcc gtggcttgcc attgtcccga tgctccattc tgatagagcg tgtacatttt
    36361 cttcacaatg gccgcgaggc gctggatctc tcgatcgatg agttcaacga atcgataatg
    36421 ccggtggtcg gggctcacgc cttgcttgac gaggtgaaac gcgttcttaa tacccgccag
    36481 tggattgttg atttcatggg cgatatcggc cgccagatgg ccaagcgccg ccactttttc
    36541 ggcctgcgac cgttgagcct ccaattcatg aattcttgcg gttcgctcac gcacacgttg
    36601 ctcaagctga gtttgcactt ccaccaaagc ctgctctgct cgacgacgtt ccgtgatgtc
    36661 atggaatgag gctacgacgg catacggacg ttcggcatga ggctcccgaa gaggctgcgt
    36721 attaatcgac aaccatcgtt gttctccgcc cggtcggcat acacccatga tcacgtccgc
    36781 gcagggctgc cccgtatgga gcgtgaccat ggcaggatgc tgctccccct caaacggcgt
    36841 gccatctttg tgaatagccc gccactcaga agtgacggat gttctcccca tcatctgttc
    36901 tgcagtcagg cccagaatct gttccgcact ggggttacac gcaatgatc
//
LOCUS       DAOQPD010000030        35818 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_485_length_35818_cov_22.635993, whole genome shotgun sequence.
ACCESSION   DAOQPD010000030 DAOQPD010000000
VERSION     DAOQPD010000030.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 35818)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 35818)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35818
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_485_length_35818_cov_22.635993"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..359)
                     /locus_tag="PK063_08955"
     CDS             complement(<1..359)
                     /locus_tag="PK063_08955"
                     /inference="COORDINATES: protein motif:HMM:NF016005.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051304 - chromosome separation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HMZ97219.1"
                     /translation="MEEPMSLSMEDAVEQPAEVAEMEAPVSEEPTAEPEVEAHAGEGD
                     VAEMAAPTPASDPALSDVRALKGILEALLFVTPDPIPVTRFLALLGAVTKQEVDQALA
                     SLSHDYEQEGRGLQLAEV"
     gene            complement(344..1123)
                     /locus_tag="PK063_08960"
     CDS             complement(344..1123)
                     /locus_tag="PK063_08960"
                     /inference="COORDINATES: protein motif:HMM:NF014654.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HMZ97220.1"
                     /translation="MDQPELPYQVKIENFEGPLDLLLHLIKKNEINIYDIPIALIAQQ
                     YLDYLSVMKELNLAVAGEFLVMAATLLHIKSRMLLPTDEVAVDEEDGPDPREELVRRL
                     LEYKQFKEAASQLDYKERLWRDTFGREPGPPIEIAKDESLLDEISLFDLVDALQGVLS
                     RHPGKRLVEIIPDNLTVRTRMSAIIEALEVHESMPFTALFEESSHRLVVIVTFLALLE
                     LIRIRVVRVFQSETFGAILVSRAFTAVAEGDLVEESEWKNL"
     gene            complement(1219..>2265)
                     /locus_tag="PK063_08965"
     CDS             complement(1219..>2265)
                     /locus_tag="PK063_08965"
                     /inference="COORDINATES: protein motif:HMM:NF024965.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HMZ97221.1"
                     /translation="GILWGTVMLPGLLFAECTSETGGKTASAVFTLHLTGTCTEAERE
                     ARAVPAKDLMRALAAGKGIDLAGVVIQGDLVLDELPAQKVDAVQGLSLEDRRVLEGLN
                     DEEVHVIRGPFVIKHSRVKGQIVNRLKRGFLLITGPVVLVHSGFDGLVDLSRTVFLGL
                     VDGSNAKFEKESYFVQDRFTQGAMFSDTRFGSHARFHRSMFSGPAIFRGADFPGLTEF
                     LEVVFEQDANFARTAFHMGTGFSGAHCRGKCDFSSTLFEREAFFLFARFDRAVTFASA
                     KFSSQADFSDASFKEADDLAKATFVRPPVMIRTARVVSTVPVAPEAGPFSQVVTIGLF
                     VAALGILIYILKAK"
     assembly_gap    2266..2365
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <2366..2938
                     /locus_tag="PK063_08970"
     CDS             <2366..2938
                     /locus_tag="PK063_08970"
                     /inference="COORDINATES: protein motif:HMM:NF017200.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97222.1"
                     /translation="ESVVEVPMLAAIQSNQLGVFEVLLLRWDHQPTPSPIMLQWQGGN
                     VKPGQTNLGSMVLALQYALEHTPTVNHTGTISVIGISYAATGTDGPSAGGVMTVGFAA
                     LLKGEQIRRGIAMTGTISKDGTIGPVGSIPDKIRAAAREGYRTILIPQGQRDDPRWNL
                     TRLAWDLNVEIKEVATVDEAYHLMTGGTLD"
     gene            complement(2966..3418)
                     /locus_tag="PK063_08975"
     CDS             complement(2966..3418)
                     /locus_tag="PK063_08975"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97223.1"
                     /translation="MSHFLFIAGALRERTSPESAELQLGAGIWGLCTSLIRDNLQKFL
                     TPESHGLVYVLKEGIRAEFSIVSPVQPFQALDELLKDELRTEARYGFVQVTPIRRWEG
                     NAPECQQLLQRVLGIEEPSELSRRLSLGMHRLSQEEYRAIVDGLGAEH"
     gene            complement(3630..4235)
                     /locus_tag="PK063_08980"
     CDS             complement(3630..4235)
                     /locus_tag="PK063_08980"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97224.1"
                     /translation="MAKKTMKKKSSAVKAARPKKGAASKASKPKKVVKAKKAAPKKPV
                     KAKKAAQPKVTAKKPVKKTAKKSTAKTAPAKAARSSKAKATPKAAKPAPKPASKPKTK
                     PASPKAKMPAEAPAVVPASKPVKSSVPEPEKASNVEMEPTQLDLEDDEEDMAEDLDDV
                     SEEEMEEEIEEELGLDNEDDDVDYLEKSEDLLDDADEYRNN"
     gene            4532..4906
                     /locus_tag="PK063_08985"
     CDS             4532..4906
                     /locus_tag="PK063_08985"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HMZ97225.1"
                     /translation="MSWRTLSLSLTFAFLMAWPSSATPPAVHVLMDSGSPYYVPAAAT
                     VTAGGAIRWDNPTPTHHTVTHDGCFDESGRCAFDSGAVEPGGTYTIPSLPPGRYPYQC
                     RIHPIMRGIIIVTDSPLLPSQT"
     gene            4988..>5475
                     /locus_tag="PK063_08990"
     CDS             4988..>5475
                     /locus_tag="PK063_08990"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97226.1"
                     /translation="MKAAAAIQEPLNLSGDILSLLAWRIPDLVAYQHAFDEWWLAPLD
                     DDFPLVRLNAVGIEMLTSMNGHITVGALVEKYGNKICGPDGQPGSWHLAHWSIPNYSL
                     CYFGTEPPGGHRHKAKWDLLLQQIRESWSGQQDFEGEEHLEDFHVHELKESDLEDGHF
                     DL"
     assembly_gap    5476..5575
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <5576..6320
                     /locus_tag="PK063_08995"
     CDS             <5576..6320
                     /locus_tag="PK063_08995"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97227.1"
                     /translation="AGGWTGTGTHANGEWLPFKDNSVDLIIDNENMADMTPVKLSREE
                     LTSGRGETAQHQEALDWIRRLRLPLDKELPEEVIFNLGPMRFVAEVWRVLKPGGRAFL
                     TEFGIEEGWPAAVKLPHHTEYEVQYSHLRQAVRWLGFQERYLSLPQFLQLKPDTKVLC
                     TGAAYTIQRFCQGLGQHFSVRAYTESELTKTLGDTLPKLQGCHYHDIADPAWFGLIDF
                     KVLLLEKPGGMPQATFTEQKSGLRWYSQR"
     gene            complement(6375..7346)
                     /locus_tag="PK063_09000"
     CDS             complement(6375..7346)
                     /locus_tag="PK063_09000"
                     /inference="COORDINATES: protein motif:HMM:NF014587.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA phosphatase family protein"
                     /protein_id="HMZ97228.1"
                     /translation="MAGASTGSSRILAGIDIGTLTCRLEIAEVTSSGQVKKLRSDRRI
                     LRLGQGVDRDRMLRTDAMARVVTTLKEWRQSIDTYQVEATSVVATSAVRDAGNRQDFL
                     DLIAREAGLQVEIISGEEEARRTTLGIRSGLPEGVSDMLAVDIGGGSTECILDRPGQP
                     LIVRSIDIGVVRLSERVLQSDPPTSEELQRAHDWIRTETGAAVADMPLPVGLTFVGTA
                     GTITALAAMDQQLPVYEAAKIHNYVLTLEAVKRLEAQLLGRSKQQREGLPGLERGRED
                     VIVAGAIILSTMMETLGMAKVLVSDLGLREGVLLHLASRLNGGSSLR"
     gene            complement(7355..7681)
                     /locus_tag="PK063_09005"
     CDS             complement(7355..7681)
                     /locus_tag="PK063_09005"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97229.1"
                     /translation="MGMLQRLSHDLRAGWVTLRHGTAKAATRALEEGELLGYRLELRK
                     VEQQLDDLHVDIGERTIELHDRGEAPDRIVADSEVARLMKQVQTLQDERTKLLLEMND
                     ITVEEA"
     gene            complement(7726..10209)
                     /gene="recG"
                     /locus_tag="PK063_09010"
     CDS             complement(7726..10209)
                     /gene="recG"
                     /locus_tag="PK063_09010"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: protein motif:HMM:NF008168.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HMZ97230.1"
                     /translation="MARPIEFACRDAYAHLPTVKNLDRFVSEQVIGALGERLHPRALE
                     VELLSLRNLFVDFHAGLTAAEQQHRLTQALQLLRRLQGQSPMVHPSADLLEGGELVHT
                     PVNIHSRQLSIESSIQFAKGVGPKRTLLLKRLGIQTIEEAIWTLPWRYDDRSTITPIA
                     KLMLAATVCICGVITRTEASRARSRRLSILDVVVQDVTGTVHAVFFNQPYLEDVLKEG
                     ARVMMAGRVVAGRRGWTDLRLEPTQFEILSGQEDELLHVGRIVPIYHETKGWTSRQMR
                     VLIQGVLAGHGAELVDVLPLSIRARHRLPPIGEAIQQVHFPPPQTDLAALDRGVTAAH
                     RRLAFEELFLLQTAMVLRQQQVKDEEKPFRFSPHVPELKKLSQILPFSLTAAQERVWR
                     EIQADMATSRPMNRLVQGDVGCGKTVVALHALVMACGSGCQTALMAPTEILAEQHYLN
                     LRPLLEAVGFKAVLLTSGGKAKDRQAVFTQLASGEAQVAIGTHALIQKNVAFDKLGLV
                     VVDEQHKFGVLQRKSLLDKGYRPDVLVMTATPIPRTLAMTVYGDLDVSVIDMLPPGRK
                     PVRTMLYSEGQRHKTWQLVSDELKAGRQAYIIYPLVEESEKIDLKAAIQGAEQLQRDI
                     FPQAQIGLLHGKMPSSEKERTMAAFKAGTIQILVATTVIEVGVDVSNATVMVIEHAER
                     FGLAQLHQLRGRVGRGAHQSLCILMASYLPRESRPKVSAEGKPEANASNAQQRLSALV
                     KSHDGFVIAEEDLRIRGPGEFLGLRQWGLPEFRAANLIRDTHLLELARQEAFAMVTQD
                     PGLALPQHQAVKAAMFRRWKGKLSLGDVS"
     gene            10431..>10678
                     /locus_tag="PK063_09015"
     CDS             10431..>10678
                     /locus_tag="PK063_09015"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97231.1"
                     /translation="MYRRNIKHILGPLAILIAIFIFYQSWLKPHYFHEMPAPPPQVIT
                     EEVAGSKGPVAPPQQAVLPEMKRSRTIDPVSIPVPRHS"
     assembly_gap    10679..10778
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <10779..11702
                     /locus_tag="PK063_09020"
     CDS             <10779..11702
                     /locus_tag="PK063_09020"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97232.1"
                     /translation="ALTEEFLKKVLTLSPDEPFPHVALADLLQEKDRLSEAAKHLAQA
                     MDRIKKDPGLQSYVKVVTAKVHRAEKVEEKFSTRNSVHFTVKYDGSEDPETWTTVLDI
                     LEAAYRDIGQKFNFFPSKPIMVVLHTKTQFQGSTGSPVWADGLFDPVLGRIQIPSQGA
                     TTDRAWLTRVLRHEFVHALIHEELGATGGAIPTWLNEGLAMQLANDSWQEVANMPPGE
                     HILIPLAALEEGWENLSAEKVGAAYMEANAATHYLIERFGMHKVHELLLHLKARQTIA
                     AAMQDRLLLSYDHFQQQWVESMGATLSTPKS"
     gene            complement(11706..12308)
                     /locus_tag="PK063_09025"
     CDS             complement(11706..12308)
                     /locus_tag="PK063_09025"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97233.1"
                     /translation="MNVKEEGAAESDGSKGRIFAGGIGADSQGKSGFMLRVYDAETGR
                     FLWEGQLNLLKVNEEGPSKVKAVIAPKPAVVIPASDRPPQVFQTFFSVRAVNPLTGRL
                     VWQDQFTPGTRKRPGSAGVSCKRCSVSPVNEPIGHIFDLVVRTYDRTSGLLLWEDSFE
                     EIDRIDESDSAPETSAYPQAIPFWHPGVADKTPMYKVTLR"
     gene            complement(13570..13827)
                     /locus_tag="PK063_09030"
     CDS             complement(13570..13827)
                     /locus_tag="PK063_09030"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97234.1"
                     /translation="MDDVKSLMCDGTTEDLGTDEVAKQAKYFLGPAVSKKRPALLKAG
                     FAEQTEMNDEYVAITFLKAVNFERYEEVLGSVRWCQNLFKT"
     gene            complement(13998..14822)
                     /locus_tag="PK063_09035"
     CDS             complement(13998..14822)
                     /locus_tag="PK063_09035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ97235.1"
                     /translation="MPLRNGLSEELNRQGNEHFARGHYTDAYACYAKALECDRLTGDH
                     RALSATLGNLGNICAVSGRRESAQSYYQEVLELQKVLGDDKGIGTTLANLGNLRADAG
                     EWDRARAYYLEALDIMTRVHDELGKAVLFSDLGLVARETGQCDDALRYYEQSLVLMRR
                     LNNQGGVADAWRMMGRTFAIQKRYDDAIACCQTSQSIAERSRDELRAGGARYVLAQCY
                     EDLGQLQAAVDLLEQVVRMDRKYALPKLTENTARLASLRARLEAEDPSPQPRRSRA"
     gene            complement(14829..15425)
                     /locus_tag="PK063_09040"
     CDS             complement(14829..15425)
                     /locus_tag="PK063_09040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97236.1"
                     /translation="MKQLLPGIWQWSWFSDEKRLDFNGLFLTVGEHRIVIDPPPMTAE
                     ASTLIRRQGALDYIIVTNRDHLREAVAYQAEFRCQLQIPEADASQMDVKPTKTYKDGE
                     LLPGGIWAIQLKDQKSPGESALYIQQGKGVLIVGDALIGKPAGALSLLPSERYGDVAK
                     AKEGLRRLLKYNFDSILVGDGASIVFGAKQAVEQVLQA"
     gene            complement(15449..15688)
                     /locus_tag="PK063_09045"
     CDS             complement(15449..15688)
                     /locus_tag="PK063_09045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97237.1"
                     /translation="MDEWEEGKLMFLEVVKGIDQGVEVVIPTKPTNSMFLISLTKGAN
                     RKFITVSEDDIIDLPTEAGIRTKVTKTLQDAVATL"
     gene            complement(15706..16248)
                     /locus_tag="PK063_09050"
     CDS             complement(15706..16248)
                     /locus_tag="PK063_09050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HMZ97238.1"
                     /translation="MKRVFIVTALVLLPLWAAHIAMAAGFFKVGEPAPAFALSSITGD
                     AVSLEQLKGKVVVLGLFHICDPCMMQGTNLQKVHEVLAGKNVAVVGINSSGNSKRDVG
                     EFLSAFPVKVTYPYLLDPNKVTDKLYGGGKFIPNVYVIDQRGVIRWQRVGNMELAGAE
                     VIVQEVEKLLASAPAGSGPM"
     gene            complement(16437..17585)
                     /locus_tag="PK063_09055"
     CDS             complement(16437..17585)
                     /locus_tag="PK063_09055"
                     /inference="COORDINATES: protein motif:HMM:NF026257.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HMZ97239.1"
                     /translation="MSEFVRVEITDLVCDGINWDLLWQLSKAHGVAPLVYRNLAAICP
                     AAVPSAIHEAYRRQNQSTTLMNTVLAKELVALLDALAAKGVMAIPFHGVTLAQVAYGD
                     LSMRECEDIELIVEHGAVSQARKVLWSHGYQLLGADNDAEADPREGHHVFLKRNGMAM
                     VKLQWGLAGYHSNFRLDRHALWGRLKPVGLPTKAVMGLCPEDLLILLCVHGTLHNWKQ
                     LKWVCDIAEFVRRKPALDWSRILFQASEWRCRRMVLLGLAMAQNLFDIVLPRTVSHEI
                     ESDTDLPVLVRRMPQQLLKHPDQGIDEDCADAVSLTVKDSVWARWKLGFILCRVDAEV
                     IHRPLPWFRFQRQLRLMSACMRPLLRSVPKEIVPVRVRHMVVGWLQSS"
     gene            complement(17870..18187)
                     /locus_tag="PK063_09060"
     CDS             complement(17870..18187)
                     /locus_tag="PK063_09060"
                     /inference="COORDINATES: protein motif:HMM:NF017239.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HMZ97240.1"
                     /translation="MPATVPVLSERTIDFSQMFPHQNSDVRITNQGGESLLFNVRTGH
                     FHRLNALGSAVWLQCTGTQSVARILSTISETFDVTATQAQSELLDVLVQLQDDGFLRI
                     EKR"
     gene            complement(18736..20166)
                     /gene="purF"
                     /locus_tag="PK063_09065"
     CDS             complement(18736..20166)
                     /gene="purF"
                     /locus_tag="PK063_09065"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HMZ97241.1"
                     /translation="MAKELPLIASDQFHDECAVFGIYGHKEAANLAYLGLYALQHRGQ
                     EASGIVSNDGEQFYVEKGQGHVADIFSQQALARLPGAMAIGHNRYSTAGGAGLKNVQP
                     LSVNFAFGNLAVAHNGNLINATMLRSELEAYGAIFQSTSDTEVIIHLIAHSRADTLLD
                     RVIDSLTQVRGAFSVVLMTDQGVIAARDPHGFRPLCLGRFRDAWIVASESCAFDLLDA
                     EYVREIEPGELVVLDHRGVTSYKPFPPTQPAMCVFEYVYFSRPDSRIFGGSAVYSIRK
                     AFGRQLAQESAVDADIVIPVPDSGVPAALGYSEGSGVPFESGLIRNHYVGRTFIEPEQ
                     SIRHFGVKVKLNAVPEVLAGKRVVVVDDSLVRGTTSRKIVKMLRHAGAKEVHMRISSP
                     PIVSPCFYGIDTPTKKELIASSHTTDEIRKYITADSLAYLSLDGMVKAAPGTPSQYCN
                     ACFTERYPISFTRAEELQLGLFEPPG"
     gene            complement(20179..22425)
                     /gene="purL"
                     /locus_tag="PK063_09070"
     CDS             complement(20179..22425)
                     /gene="purL"
                     /locus_tag="PK063_09070"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HMZ97242.1"
                     /translation="MKSLVITQAILEQHKLSEEEYKKILEILGREPNWTELGMFSAMW
                     SEHCSYKSSRIHLKKLPTTGPRVVQGPGENAGAVDIGDGLCAVFKMESHNHPSFIEPY
                     QGAATGVGGILRDIFTMGARPIALLNSLRFGGLDNANTRHLLKGVVSGIAGYGNCMGV
                     PTVGGEIVFNDIYALNPLVNVFCLGIARKDKIFLGKAAGVGNPVIYFGSKTGRDGIHG
                     ATMASDSFDEQAAQKRPTVQVGDPFTEKLLLEACLELMAGDCLVGIQDMGAAGLTSSA
                     CEMASREGTGVELELADVPRREPGMTPYEIMLSESQERMLMVAKAGREDEVIKICRKW
                     DLDVAVIGRVTDTGKVVLKENGQIVAEIPAKALADDGPRYDRPSAPPAYQEMLQSLNY
                     DALPDVKDANATLLELLGAPTIASKRWVYEQYDHMVRTNTMVRPGSDAAVLRVKGTNK
                     ALALSVDCNGRYCLLNPYEGAKIAIAECARNLACSGAEPIGVTDCLNFGNPQRPEVMW
                     QFVLAIEGLKDACEALSVPIVSGNVSLYNETNDLSIYPTPMIGMVGLIEAADRTATQW
                     FKQAGDVIILLGRTREDLGGTEYLKIVHHREQGSPPLLNLEDERAVQACTIGLIREGL
                     VQSAHDCSDGGLAVALAECCVSGPNGHVGAVVQLPLDGLRRDALLFGESQSRIVLSVK
                     QEQVDNVLSAARNAGVPASRIGVVGGSRLVIRVDGDQRVAGCTIDLEVTSVQERWALA
                     IPRALGQD"
     gene            complement(22493..23215)
                     /gene="purQ"
                     /locus_tag="PK063_09075"
     CDS             complement(22493..23215)
                     /gene="purQ"
                     /locus_tag="PK063_09075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HMZ97243.1"
                     /translation="MNIGVVVFPGSNCDHDCEYIFKDVLGQSVKMIWHKDTLPAGLDA
                     VVLPGGFSYGDYLRTGAIARFSPVMGAVKTFARDGGLVIGICNGFQILLEAGLLPGVM
                     LRNTSLNFICKDVYVKVENAATRFTNRCESGQVLKIPIAHADGNYYTDPVTLGGIKAN
                     AQVIFRYCTAEGKITPEANPNGSLDNIAGIMNADGNVLGMMPHPERSAETLLGNEDGR
                     LIFLSMLSAFGKSEQPSRLVGV"
     gene            complement(23333..23572)
                     /gene="purS"
                     /locus_tag="PK063_09080"
     CDS             complement(23333..23572)
                     /gene="purS"
                     /locus_tag="PK063_09080"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HMZ97244.1"
                     /translation="MKAKIHVTLKQGILDPQGKAIEHALDSLGFKNAANVRVGKYMEV
                     DVNETDSAKADAQVKQMCEKLLANTVIEEYRYELQ"
     gene            complement(23569..23793)
                     /locus_tag="PK063_09085"
     CDS             complement(23569..23793)
                     /locus_tag="PK063_09085"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97245.1"
                     /translation="MNRFLRFFLDYGLVLAILVWAATVALMAYHLDESPWRWAFILLS
                     MAGLGTIGVIFWIRKYVNKTAQTQRVGKVQ"
     gene            complement(23913..24626)
                     /locus_tag="PK063_09090"
     CDS             complement(23913..24626)
                     /locus_tag="PK063_09090"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HMZ97246.1"
                     /translation="MTGEPAGTMLYEGKAKKIFTTERPDQVLQYFKDDATAFNAQKRG
                     TIVDKGVVNNKVSERLFKLLEQQGIQTHFIERVSDREMLTKKVTIVPVEVVVRNVVAG
                     SLAKRLGLKEGAAIEPAIIEFYYKDDALGDPLVNDDHLRVLNVATPAVLREMRELGHK
                     INAVLLPFFKERRMLLVDFKLEFGVFHNRLILADEISPDTCRFWDQATKESMDKDRFR
                     KDLGKIEEAYQEVLKRVCE"
     gene            complement(24641..25438)
                     /locus_tag="PK063_09095"
     CDS             complement(24641..25438)
                     /locus_tag="PK063_09095"
                     /inference="COORDINATES: protein motif:HMM:NF018484.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chlorite dismutase family protein"
                     /protein_id="HMZ97247.1"
                     /translation="MMAALIMRIVLMVALVFGAAVSPVGATEREALLTQPGVYGTFAA
                     FQMDHDWWDLNGEARVIAVSEVKGLIEQFSQKIVIESYLLRGLSDHADFMFRIHAHAL
                     SDTQQFLTSLLGTRLGRHLVATTYLHGMTKPAAYAAGFPESMKQALQSPAPETGTKSY
                     AIVIPIRKDADWWALDQDSRARLMQEHTQAALPYINTVKRKLYHSSGLDDFDFITYFE
                     TDKLEEFHSLIRALEQVKEYRHDRRFGHPTLLGTIRPLDDILELFAR"
     gene            complement(25435..>25614)
                     /locus_tag="PK063_09100"
     CDS             complement(25435..>25614)
                     /locus_tag="PK063_09100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HMZ97248.1"
                     /translation="GVGFQELVNRDPFITTHLKPSEITACFDPMYYLRHLDQVFRRVF
                     GALAIPAARRRKRRA"
     assembly_gap    25615..25714
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<25715..26924)
                     /gene="purB"
                     /locus_tag="PK063_09105"
     CDS             complement(<25715..26924)
                     /gene="purB"
                     /locus_tag="PK063_09105"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HMZ97249.1"
                     /translation="MIERYTRPRMSAIWDLTHKYEIWLEVELQACAAFERAGQIPRGT
                     SAKIRKKAKIDVARIAEIEKVTKHDVIAFLESLMASVGPEHRYLHMGLTSSDIVDTSL
                     AVQMTEALDLILEDLDELIAVLKKRALEHRHTVMVGRSHGIHGEPVSFGFKLAIWYEE
                     ACRHRTRLEAARKDIAVGKLSGAMGTFAHQGPEIEEYVCAKMGLASDPVSNQIVQRDR
                     HAAYASALALLAATIEKIATEIRHLQRTEVLEAEEYFSEGQKGSSAMPHKRNPIASEN
                     LCGLARLVRSNSLAAMENVALWHERDISHSSVERVIMPDSTILVDYMLARVTDLVRNL
                     VVYPERMQRNLDLTGGLVYSQRLLLALIDKGAQRKESYEAVQRNAMTAWKGGVGFQEL
                     VNRDPFITTHL"
     gene            complement(27021..27473)
                     /gene="nusB"
                     /locus_tag="PK063_09110"
     CDS             complement(27021..27473)
                     /gene="nusB"
                     /locus_tag="PK063_09110"
                     /inference="COORDINATES: protein motif:HMM:TIGR01951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HMZ97250.1"
                     /translation="MASRHQARERAVQILFQYDIHGQAGPWLDDFWTQYPLNDELRVF
                     AERLVAGVREHKKELDALIGTHATNWKVGRMPIIDRNILRLGCFELLFVPEVPAKVTL
                     NEAIELAKSFGDEEASKFVNGILDKVLGSDSRLERKRAFPELPVVGSD"
     gene            complement(27487..28026)
                     /gene="ribH"
                     /locus_tag="PK063_09115"
     CDS             complement(27487..28026)
                     /gene="ribH"
                     /locus_tag="PK063_09115"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HMZ97251.1"
                     /translation="MKLRKGSQDATGLTVGIVASKFNKFVTSRLLTECVKALTKAGAS
                     DEAIEVVRVPGAFEIPLVARQLARSGRFDAVICLGAVIRGDTPHFEYISTEVSRGILQ
                     ASMESNLPVIFGVLTTDTVAQAIERADPAKLNRGADAAKTAIEMVNVMRQLKKEESED
                     VPPGPAPRRAGRTAARAKR"
     gene            complement(28176..29384)
                     /locus_tag="PK063_09120"
     CDS             complement(28176..29384)
                     /locus_tag="PK063_09120"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HMZ97252.1"
                     /translation="MATPFNSIEEAIRDIKKGKFIILVDDEDRENEGDLVMAASKVTP
                     QAVNFMAKHARGLICLALTPERVEELQLAPQAAENTATFGTAFTVSIDARKGITTGIS
                     AADRATTIHVAIDPRCSPADLARPGHIFPLKAQVGGVLRRAGQTEGSVDLARLAGLYP
                     AGVICEIMNEDGTMARVAELTKFAKRHKLKMVTIKALIEYRMHRETFVRRAASAFLPT
                     TFGDFEAIAFENDIDGATHIALVKGQVDADTPMLVRVHSGCLTADVLGSLRCDCREQL
                     HRAMEIIQKDGRGVLLYLNQEGRGIGLLNKIRAYGLQDSGSDTVEANLQLGFKADLRD
                     YGVGAQILVQLGLHKIRLITNNPRKIVGIEGYGLKVVERVPIEIAPRADNEKYLRTKK
                     AKLGHLLKKV"
     gene            complement(29449..30690)
                     /locus_tag="PK063_09125"
     CDS             complement(29449..30690)
                     /locus_tag="PK063_09125"
                     /inference="COORDINATES: protein motif:HMM:NF019310.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HMZ97253.1"
                     /translation="MKSLGNVRTLGTALRSGHWPTLAGAWLHLTVSFMVWVLFGALAV
                     PMGAELHLTATQQSVVVALPLLSGALLRIVTGWACDWSGAKRTGLWVLGLQLIAVLWA
                     ALSGTQYVELLAIALLLGAGGASFAVAMPVASRAYPAAHQGLVLGLVASGNIGTVLVL
                     LLAPQWEGQLGWHGACGIMALPILLAIGLFARVVREEPHTISVAEDAWWQQAWGMVQV
                     PSVYWLCLVYAITFGGFVGLTSFLPVLLHDQYGSDPIVGGAIAALCGLTGSLIRPVGG
                     YVADRWGGLPALAGVFMVLAAVTAFAASLPLLPWLASLLMVTIAVMGFGNGVIFQIVS
                     EWFPKDIGLASGLVGAAGGIGGFFVPIGFGLLREAMGTFVPGFLGLALVSAAAAMTVG
                     SALRWRPRAVASATNAEGFSR"
     gene            30859..31890
                     /locus_tag="PK063_09130"
     CDS             30859..31890
                     /locus_tag="PK063_09130"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-32"
                     /protein_id="HMZ97254.1"
                     /translation="MRQRKPKHNTDSDSDSAAELDEDDSLEPEALEPTDEEVTEEHEA
                     AERQPSKESPSAPLSTSLVPVTTLQQYLTEIRRYPYLSKEEELRLFEEYQLRGSRDAA
                     MKLILANLRVSVSIASEYLHTGADHMDLIQEGNVGLLQAIKKFDPTKNVRFYAYAAWW
                     SRAYILRYLLNTYRLIKVGTTQDQRKLFYNLKKEKAKLEREGFAPDSKLLADRLNVRE
                     RDVIEMDQRLGSWELSLDQPIGQEHDGTLMDVLPAHEQPADEQLADTQLKALFRRKLA
                     EFTKTLDEREEDILRNRILSETPLTLEDMGAKYGITKERTRQLEARIIKRLRDFIKKD
                     VKDFDRLRM"
     gene            31871..33430
                     /locus_tag="PK063_09135"
     CDS             31871..33430
                     /locus_tag="PK063_09135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97255.1"
                     /translation="MTVSGCKTGASIRIVLTILMLTTLVESGCPRPSHAASLITQENA
                     RPGQSDWVLTDPADHEVEGYASATSIQRGEPLRLYIHSTDPHVTVDIYRMGWYGGTGA
                     RLVRGGITLPGARQPMPTPDPVTGLIECRWQVSYTLTTETHEKNDWLSGVYLAKLTGS
                     ASGKQSYIIFVVREDDRPSEFLFQSSVTTFQAYNNWGGKSTYPSNSRDEQWARKVSFN
                     RPYARSQHPQGGSGIGAGEFLTAMSIHPTRALSTAGWEYNMVRWLERHGYDVTYSTDI
                     DTHTRAEFWKGHKTWLSVGHDEYWSAEMRRHVEEARDHGVGLGFFSANTCYWQIRLEP
                     SLLTGEPNRTMVSYKEVAWNEDPLALDGDPSNDQLITVQWRESPVQRPEQALLGVMYG
                     TVPVDGDILITQPEHPLFNGVDLPPDHRLPGLLGYEIDQVFANGPAGLTVLAHSSYPR
                     DGEAVYGDMTLYQAQSGAFIFAAGTIQWSWGLDDYNAPTLRTARSSQAAQRITGNILR
                     LLASPASSPAH"
     gene            33744..34046
                     /locus_tag="PK063_09140"
     CDS             33744..34046
                     /locus_tag="PK063_09140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HMZ97256.1"
                     /translation="MATESKEKKSTAAKNFQPLGDRLFVTYTEEMERTSGGIYVPDSA
                     KEKPQRGIVQAIGKKVENIKVGDQVLFDKYSGSKLRIEDEECLILKEEDILGIFTH"
     gene            34093..35736
                     /gene="groL"
                     /locus_tag="PK063_09145"
     CDS             34093..35736
                     /gene="groL"
                     /locus_tag="PK063_09145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247953.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HMZ97257.1"
                     /translation="MMAKQLLYSEAARAAILRGVNQLADAVKATLGPKGRNAILDKKF
                     GAPTITKDGVTVAKEVELKNPYENMGAQLVREVASKTSDTAGDGTTTATVLAQAIYRE
                     GVKNITAGANPMEIQRGINKAVEVVIGELKKLSKPCQNKTEISQVGTISANNDKTIGD
                     LIAEAMEKVGKDGVITVEEAKSMTTSLDVVEGMQFDRGYISPYFVTNAERMEAVMDEP
                     LILINEKKVSSMKDLLPVLEQVAKLGKPLIIIAEEVEGEALATLVVNKLRGTLNVSAV
                     KAPGFGDRRKAMLEDIAILTGGQVISEDLGLKLENVKLTDLGRAKRVTIDKDNTTIVE
                     GHGDPKKIEGRVKQIKAQIEETTSDYDREKLQERLAKIVGGVAVINVGAATETEMKEK
                     KARVEDALHATKAAVEEGIVPGGGTAYLRCLKGLDSLKDLPLEQKVGVDIVRRSLEEP
                     VRQIAANAGAEGSVVVGRVREDKNPNGGYNAAADEYVDMIKTGIIDPTKVSRCALQNA
                     ASVAGLMLTTEVMITELPEEKKEPAGGHAGHNHGMEGMY"
BASE COUNT         7978 a        10813 c         9241 g         7386 t
ORIGIN      
        1 acctccgcta actggaggcc tcggccctcc tgttcgtagt catgactcag actggccagt
       61 gcctgatcaa cctcttgttt tgttacggcc ccaagcaagg ccaagaatcg cgtgacagga
      121 attgggtcgg gcgtcacaaa gagcaaggcc tcaaggattc ccttcaaggc tcgcacgtcg
      181 gaaagagcgg gatcagacgc tggtgtcggc gcagccatct ccgccacgtc accttcgccg
      241 gcgtgggcct ctacctcagg ttcagcagtc ggctcttcgg acactggcgc ctccatttca
      301 gccacctcgg caggctgttc gacggcgtcc tccatgctga gactcatagg ttcttccatt
      361 cagactcctc cactaaatcc ccttctgcca ccgccgtaaa ggcacgggag acaagaatcg
      421 ccccgaaggt ttcgctttga aaaacccgca cgaccctgat gcggatcagc tcaagtaatg
      481 ccaggaatgt cacaatgacg accaggcgat gactcgactc ctcaaacagc gccgtgaacg
      541 gcatggattc gtgcacctca agcgcctcga taatcgcgct catgcgtgta cggaccgtca
      601 ggttgtccgg gatgatttca accaggcgtt ttccgggatg tcgggacaga acgccctgca
      661 acgcatcgac cagatcaaac agcgaaatct cgtcgagcag gctttcatct tttgcgattt
      721 cgatcggcgg accgggctca cggccaaacg tatcccgcca gaggcgttcc ttataatcca
      781 gctgcgaagc ggcctccttg aactgcttat attcaagcag tcgccgaacc agttcttctc
      841 gaggatcagg cccgtcttcc tcgtcgacag cgacttcgtc cgtcggcaat aacatacgcg
      901 acttgatgtg cagcaacgtg gctgccatca ctaaaaactc ccccgctacc gcaaggttca
      961 attccttcat caccgacaga tagtccagat actgctgagc gatcagcgca atcggaatat
     1021 cgtagatgtt gatttcgttt ttcttgatga gatgcaacag gagatcgagc ggaccttcaa
     1081 aattctcgat cttgacttgg tagggcagtt caggttggtc catcaggtac cagacgctcc
     1141 cttggacaaa tttttaatct tataccaatt tatggtggga tggggcaagg ctaaaactat
     1201 atgttggggt tcaggcaact acttcgcttt gaggatatag atcaaaattc ccaacgccgc
     1261 cacaaacagc ccgatcgtca ccacttggga aaaaggaccc gcttccgggg cgacgggcac
     1321 agtcgaaacg acccgcgcag ttctgatcat gaccggcggg cgaacgaacg tagcctttgc
     1381 taagtcgtca gcctccttga aggacgcgtc ggaaaaatcg gcttgggaac tgaatttcgc
     1441 cgaggcaaaa gtcaccgccc ggtcaaatcg agcaaacaaa aagaacgcct ctcgctcaaa
     1501 cagcgtcgat gaaaaatcgc acttgccacg acagtgcgca ccagagaatc cggttcccat
     1561 atggaaggcc gtacgagcaa aattcgcgtc ctgctcgaat accacttcca gaaactcagt
     1621 caggccagga aaatctgcgc cgcgaaagat ggccggaccg ctaaacatag accgatgaaa
     1681 ccgtgcatgc gatccgaagc gggtatcgga aaacatcgcg ccctgcgtga agcggtcctg
     1741 aacaaaataa ctttccttct cgaacttggc attcgaccca tcaaccagac cgagaaagac
     1801 tgtccgtgac aaatcgacga ggccgtcgaa accgctgtgc accaacacca ccgggccggt
     1861 aatcagcaaa aacccgcgct tgagacgatt cacgatctgc cccttcaccc gggagtgctt
     1921 gatcacgaat ggcccgcgaa tgacatgcac ctcttcatcg ttgagccctt cgagcacccg
     1981 gcgatcttcg agggacaggc cctgcaccgc gtcaaccttc tgcgccggta actcgtcaag
     2041 caccagatcg ccctgaatga ccactcccgc cagatcaatg cccttcccgg ccgccaaggc
     2101 tcgcatgaga tctttggccg gaacggcacg agcttcccgc tccgcttccg tacaggtgcc
     2161 ggtcaagtgc agagtgaaga ctgcgctggc agtctttcca ccggtctcac tcgtacattc
     2221 ggcgaacaag agaccgggaa gcatgacggt tccccagaga atcccnnnnn nnnnnnnnnn
     2281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2341 nnnnnnnnnn nnnnnnnnnn nnnnngagtc agtcgtcgaa gttcccatgt tggcggctat
     2401 tcagtccaac cagcttggcg ttttcgaagt gctcctgctg cgctgggatc atcagccgac
     2461 cccttctccg atcatgctgc aatggcaagg cgggaacgtc aaacccggac agacgaacct
     2521 tgggtctatg gtcctcgcct tacaatatgc tctcgaacat acaccgacgg tgaaccatac
     2581 cgggaccatc agtgtcatcg gcatttcgta cgccgcaacc ggtaccgacg ggccgagtgc
     2641 cggaggcgtc atgacggtgg gatttgccgc actcctcaag ggcgaacaga tccgccgcgg
     2701 cattgccatg acgggcacga tttccaagga cggcacgatc ggcccggtgg gaagcatccc
     2761 cgacaagatc cgggcagcag cccgcgaggg ataccgcacc atcctcatcc cgcaaggtca
     2821 acgagacgac ccccgctgga atctcacccg ccttgcctgg gatctcaacg tagaaatcaa
     2881 agaagtcgcc acggtggatg aggcctacca tctcatgaca ggtggcaccc tcgactagcc
     2941 gcttccggaa ggaagcgcga tctgattagt gttccgcccc caacccgtcg acaatcgctc
     3001 ggtattcctc ctgtgaaaga cggtgcatcc caagactgag ccgacgggac aattctgatg
     3061 gttcttcgat gcccaggact cgctgaagca gttgctggca ctcgggcgcg ttcccctccc
     3121 agcgtcgaat cggtgtgacc tgtacgaatc catagcgggc ttccgtccgc aactcatctt
     3181 tcagcagttc gtccaacgcc tgaaacggct ggaccggcga gacaatcgaa aattccgcgc
     3241 gaatgccttc tttcaacaca tacaccaggc catgtgattc gggcgtcagg aacttttgaa
     3301 ggttgtcgcg gatcaaggag gtacacaggc cccagatccc ggcgcccagc tgcaactcgg
     3361 cactttccgg ggaagtccgt tcgcgtaagg ccccggcgat aaaaagaaag tggctcatga
     3421 gagggctgag cgattggaat tggcagacgt cgccgcgagc cgcacccgaa cgatgcgaca
     3481 cgatcggaag gcgcgacgcg acttcattcg agacgcggcg caacacacca tgacatcaga
     3541 catgttcagt gggaccttca ctgacgagaa tcaatgaggc acgcagaggc acagaccgag
     3601 atcacccggt acagcggcat caactgaaac taattgtttc gatactcatc tgcatcgtcg
     3661 agcagatctt cagacttctc gagataatcg acatcgtcgt cctcattgtc gaggccgagt
     3721 tcctcttcga tttcttcttc catttcttct tctgatacgt catccagatc ttcagccatg
     3781 tcctcttcgt catcttcgag gtcaagctgg gtcggctcca tctcgacgtt tgaggccttt
     3841 tcaggctccg gcacagaaga tttcaccggc ttcgatgcag gaaccaccgc gggggcttcc
     3901 gcaggcatct tcgcctttgg tgaagcaggc ttcgttttgg gcttggatgc gggtttcggc
     3961 gcaggtttgg cggcttttgg tgtcgctttc gccttggagg aacgcgcggc tttcgccgga
     4021 gcagtcttgg cagtactctt tttagcggtc ttcttcaccg gcttcttcgc cgtcaccttc
     4081 ggttgcgccg ccttcttggc cttcaccggc ttcttgggtg cagccttctt cgctttcacg
     4141 actttcttcg gcttgctcgc cttggaagcc gcgccctttt tcggccgcgc agctttcacc
     4201 gcagagcttt tctttttcat ggtcttcttc gccattccac gtcctcctct caggtcttca
     4261 acatggcacg tcggtggtaa agcggcctcc atctagcatg aaccaatagg ttcttgcaac
     4321 ctctccgatt cacatcgaaa ttgtgtcatc gtgcaacgcc aagccaaacc ttccagcagc
     4381 ctacactcac tcttggtgcc ttcgattcgg tcatccggtt tgcgctgttt caaagaggcc
     4441 cagcctagga gcagtctggt gaatccttcc gcatcgcgcc tgtctctatg tataatgaag
     4501 agatcgatat tcacatggag tcatgtacct catgagctgg cgcacactct ctctaagtct
     4561 cacgttcgca ttcctgatgg cttggccctc ctccgcgacc cctccggcag tccatgtctt
     4621 gatggatagc ggttccccct attacgtgcc cgctgccgcc accgtcaccg caggtggcgc
     4681 catccggtgg gacaacccaa cgccgaccca tcacaccgtg acgcacgacg gctgttttga
     4741 cgaaagcgga cgttgcgcct tcgactccgg cgcggtggaa ccgggtggca cttataccat
     4801 tcccagcctg cctccaggcc gatacccgta tcaatgccgc attcatccca ttatgcgcgg
     4861 catcatcatc gtgaccgact ctcccctcct gccctcacaa acctagagac gaccctcctg
     4921 ggttcttgca ggtcagcgtg agcctcgtgt aggctgcggc ttcttgtaat ctgaatcgtc
     4981 tgacgcgatg aaagctgccg cagccattca agaaccgctc aatctgagcg gcgacattct
     5041 gagcctgctc gcctggcgca ttcccgacct ggttgcgtat cagcatgcct ttgacgaatg
     5101 gtggttggcg cccctggatg atgatttccc gctcgtccgc ctgaacgcag tcggcattga
     5161 aatgctcacc tccatgaacg gccacattac ggtcggtgca cttgtggaga aatacggcaa
     5221 caagatctgc gggcctgacg gtcagccagg atcctggcat ctggcacact ggtcgatccc
     5281 caactattca ctctgctatt tcgggaccga accgccgggg ggccaccggc acaaggctaa
     5341 atgggacctc ctgctccagc aaatacgaga aagctggtcc ggccaacagg atttcgaagg
     5401 cgaagaacat ctcgaagatt tccatgttca cgagctgaaa gaaagcgatc tggaggacgg
     5461 ccatttcgat ctcatnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnggccg
     5581 gtggctggac aggcaccggc actcatgcca acggggaatg gctgccgttt aaggataact
     5641 ccgtcgacct catcatcgac aacgaaaaca tggcggacat gaccccggtc aagctcagcc
     5701 gggaggaact cacgagtggc cggggggaaa ccgcgcaaca tcaggaagca ctggattgga
     5761 tcaggcgact gcggttgcca ctcgacaaag agctaccgga agaagtgatc ttcaatctgg
     5821 gaccgatgcg attcgtcgcc gaagtctggc gagtcctcaa accgggcggt cgggcatttt
     5881 tgacggagtt cgggatcgaa gaaggctggc ctgccgcggt gaaacttcct caccacaccg
     5941 aatacgaagt gcagtatagc catttgcggc aagcggtccg gtggctgggc tttcaggagc
     6001 gctatttgtc gctcccgcaa tttttacagc tcaaaccgga tacgaaggtc ctttgcaccg
     6061 gcgcagccta tacgattcag cggttttgcc agggacttgg ccaacacttc tcggtgaggg
     6121 cctacaccga aagtgagctc acgaagaccc tcggtgacac ccttccgaaa ctgcagggct
     6181 gccattacca cgatattgcc gatccagcct ggttcggcct gatcgacttc aaggtcttac
     6241 ttctggaaaa accaggcggc atgcctcagg ccaccttcac cgaacaaaaa agcgggctgc
     6301 gctggtactc ccaacggtaa cgatcagcac gtcatccctt caccaacgag agcctatcac
     6361 cgtcaggccg ccactcagcg caacgaggaa cctccgttca accggctcgc caggtggagc
     6421 agcacccctt ctcgaagccc caggtcgctg accagaacct tcgccatgcc cagcgtctcc
     6481 atcatcgtac tgaggatgat cgctccggcg acaatgacgt cctcccggcc tcgctccagc
     6541 cccggcaacc cctcccgttg ctgtttcgat cgaccaagaa gctgtgcctc caggcgcttc
     6601 accgcctcaa gcgtcagaac atagttgtga attttcgctg cttcatagac gggtaattgc
     6661 tggtccatag ccgccaacgc ggtgatcgtt cctgccgtac ccacaaatgt cagtccgacc
     6721 ggcaagggca tatccgcaac ggccgctccg gtctcagttc gtatccaatc atgcgcccgt
     6781 tgaagttctt cggaggtagg cggatcgctc tgcagcacgc gttcgctcag gcgcaccaca
     6841 ccaatatcga tggatcgcac aatgagcggt tggccgggtc gatccagaat acattccgta
     6901 cttcccccgc cgatatccac cgccagcatg tcagagacac cttccggcag accggaacga
     6961 atccccaagg tggttcgtcg cgcctcctcc tcaccggaga tgatttccac ttgcaagccg
     7021 gcctcacgtg cgatcaggtc taaaaagtct tgtcggttcc cggcatcgcg cacggcactc
     7081 gtcgcaacca ccgacgtcgc ctccacctga tatgtatcaa tactctggcg ccattccttc
     7141 agcgtcgtca ccacccgcgc catagcgtcg gtccgcagca tgcgatctcg atcgaccccc
     7201 tggccgagcc ggagaattcg tcgatcagat cgcagttttt tgacctggcc tgaggaagtc
     7261 acctcagcaa tctccaggcg gcaggtcagg gttccgatat cgatgccagc caagattctg
     7321 gacgaacctg ttgatgcgcc agccatgaaa tctttcaggc ctcttctacc gtgatgtcat
     7381 tcatttccaa taggagtttg gtccgttcat cctgcagcgt ctgcacctgt ttcatcagac
     7441 gtgcgacttc agaatcagcc acaatacgat ccggcgcctc gccgcggtca tgcaactcga
     7501 tcgtccgctc accgatgtcc acatgcagat catccagctg ctgctccacc tttcgcaatt
     7561 ccaatcgata ccccagaagc tcgccctctt ccaatgctct cgtggcagcc tttgcagtgc
     7621 catgtcgtaa tgtcacccat ccggcgcgaa gatcgtgact caaacgttgc agcattccca
     7681 tcgatcagtc ctccgctcct tcggcagcac cattgcgcca actaactaac tgacgtcccc
     7741 caaggacagc ttgcccttcc agcgacgaaa catggccgcc ttgaccgcct gatgctgggg
     7801 caacgccagg cccggatcct gggttaccat cgcgaacgct tcttgtctcg ccagctccaa
     7861 caagtgtgta tcacgaatga gattggctgc ccgaaactcc ggcagtcccc attgccgcaa
     7921 tcccaagaac tcgccgggcc ccctgatgcg aagatcttct tccgcaatga caaacccgtc
     7981 gtgtgatttc accagcgcgg acaagcgttg ctgggcattg gaggcattgg cctcaggctt
     8041 tccttcagca ctcaccttcg gtctggactc tcgcgggaga taggacgcca tgaggataca
     8101 caaggattga tgcgcccctc gtcctactcg tccgcgcaat tgatggagtt gggccagtcc
     8161 gaatcgttcg gcatgttcga tgaccatgac ggtggcattg gacacatcca cccccacttc
     8221 aatgaccgtc gtcgcaacca aaatctgtat tgtgccggcc ttgaaggctg ccatcgtacg
     8281 ctctttttca gacgacggca tcttcccgtg caacaagccg atctgcgcct gcggaaagat
     8341 gtcgcgctgc aactgttccg ctccctgtat cgccgctttg agatcaatct tctcggactc
     8401 ttctaccagc ggatagatga tatacgcttg ccgtcccgcc ttcagctcat cgctcaccag
     8461 ctgccaagtt ttgtggcgct gaccttccga gtagagcatg gtccgcaccg gcttgcggcc
     8521 cggtggcaac atatcgatga ctgaaacatc cagatcgcca tagacagtca tcgccaaggt
     8581 gcggggaatc ggcgtggccg tcatcaccag cacatccggt cgatatccct tgtcgagcag
     8641 cgactttcgc tgcagcacac caaacttatg ctgctcgtcc actaccacca accccagctt
     8701 gtcgaatgcg acgttcttct gaatcagcgc atgggtgccg atggccacct gcgcttcccc
     8761 cgatgccaac tgcgtgaaga cagcctggcg atctttggcc ttccccccgc tcgtgagcaa
     8821 cacggccttg aaaccaaccg cctctaggag aggcctgaga ttcagatagt gctgttcagc
     8881 cagaatttcg gtgggagcca tcagcgctgt ttgacaaccg gagccacagg ccatcaccag
     8941 ggcatgcaac gccacgaccg tttttccaca ccccacatcc ccctgcacca gacgattcat
     9001 ggggcgcgag gtcgccatat cggcttgaat ctctcgccat acccgttcct gcgcagccgt
     9061 cagtgagaag ggcaaaatct gcgacagttt tttgagttcc ggcacatgag gactgaatcg
     9121 aaacggtttc tcttcgtcct tcacctgctg ttgcctcaac accatggccg tctgaagcag
     9181 aaacaattcc tcgaaggcca atcggcgatg ggcagccgtt accccgcggt caagcgcggc
     9241 caggtcggtc tgcggcggcg ggaaatgtac ctgctgaata gcctcgccaa ttggcggcaa
     9301 ccggtggcgc gcgcgaatgg acaacggcaa aacgtccaca agctccgcac cgtgcccggc
     9361 cagtaccccc tggattaaga cgcgcatctg gcgagaggtc cagcccttcg tctcatggta
     9421 aatcgggacg atgcgtccga cgtgcagcaa ttcatcttcc tgaccgctca atatctcaaa
     9481 ttgcgtcggc tccagccgaa gatccgtcca tcctcgccga ccggcaacta cacgcccggc
     9541 catcatgacg cgtgccccct ccttcaacac gtcttccaga tagggttgat taaagaacac
     9601 cgcgtgcacc gttccagtta cgtcctgaac aacgacgtcc agaatcgaca accggcgaga
     9661 gcgtgcgcgc gaagcttccg ttcgagtgat caccccacag atacagaccg tcgccgccaa
     9721 catcagctta gcaatcggcg tgatggtcga tcgatcatca taccgccatg gcaaagtcca
     9781 gattgcctct tcgatcgtct ggatgccgag acgtttcaag aggagggtgc gcttcggacc
     9841 aacacccttc gcgaactgaa tcgatgactc tatagacagc tgtctggaat gaatattcac
     9901 gggagtgtga accagctccc ctccctccag aagatcggcg gacggatgca ccatcggcga
     9961 ctgcccttgg agccggcgaa ggagctggag ggcctgcgtc agtcgatgtt gctgttcggc
    10021 agccgtgagt ccggcatgaa aatcgacgaa cagattgcgt aaggagagca gctcaacctc
    10081 aagcgcgcgc gggtgaagtc gctcaccgag cgcgccaatg acctgttccg acacaaaacg
    10141 gtcaagattt tttactgtcg gcaggtgggc ataggcatca cggcaagcaa attcaatggg
    10201 tcttgccact cgctgcagga atgaccggaa agactcatgg ggatcagaag aatcaggacg
    10261 tggcatccta ggcgggatcg taccataggc tgcctgcctg ctcaatgaag gaccggcgat
    10321 gacgaacaca ccctcccgtg accaccattc gcccgctttt gcgactttcc ttggtcgtcc
    10381 actacctcga tgctagagta acttcgtgta ggactcacgg aaggacacct atgtatcgac
    10441 gcaatatcaa gcatattctc gggccgttgg ccattctcat tgctatcttc attttctatc
    10501 agtcctggct caagccgcac tatttccacg agatgccagc accgccacct caagtcatta
    10561 cagaagaggt cgccggatcc aaaggtcccg tggcgcctcc gcaacaagcg gtgctaccgg
    10621 aaatgaaacg atccagaacc attgatcccg tcagcattcc cgtccctcgg cactccgann
    10681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnngc gctgacggaa gaattcttga
    10801 aaaaggtgct gaccctatct ccggatgagc cgttcccgca tgtggcgctg gcggacctcc
    10861 tccaggaaaa agatcgcttg tcggaagcgg ccaaacatct cgcacaggca atggatcgca
    10921 taaaaaagga tccagggctg cagtcttatg tgaaagtcgt gacggctaag gtccatcgcg
    10981 cggaaaaggt agaagagaag ttttcaacgc gtaacagcgt ccattttacg gtcaagtatg
    11041 acggcagtga ggatccggag acctggacaa ccgtgctgga tattctcgag gcggcgtatc
    11101 gagacatcgg ccagaagttc aatttctttc cgtcgaaacc tattatggtg gtgctgcaca
    11161 ccaagactca gtttcaggga tccaccggca gccccgtgtg ggcagatggc ttattcgacc
    11221 ctgttctggg gcgcatccag atccccagtc aaggcgcaac gacagatcgc gcctggctga
    11281 ctcgcgttct ccgtcacgaa tttgtccacg cgctgattca tgaggaactg ggagcaaccg
    11341 gtggagccat acccacctgg ctcaatgaag ggttggctat gcagctggcc aatgattcct
    11401 ggcaggaggt cgcaaacatg cctccggggg aacatatctt gatacccctg gcggctcttg
    11461 aggagggctg ggaaaactta tcggccgaaa aggtgggcgc cgcatacatg gaagccaatg
    11521 ccgctaccca ctaccttatt gaacgattcg gcatgcacaa ggttcatgag ttacttcttc
    11581 acttgaaggc gcgccagaca atcgccgctg ccatgcagga ccgcctgctg ctctcctacg
    11641 accatttcca gcaacagtgg gtggagagca tgggcgccac cttatccacg cccaaatcgt
    11701 aactgtcagc ggagggtcac tttgtacatg ggggttttgt ccgcaacccc cggatgccaa
    11761 aatggtattg cctgtggata ggcacttgtc tccggcgcgg aatcagactc atcaattcga
    11821 tcgatttcct cgaacgaatc ctcccacaac agcaggcctg atgtgcgatc gtaggttcgc
    11881 acaaccaagt caaaaatgtg tccgataggc tcattgacag ggctcaccga gcacctctta
    11941 catgacaccc ctgcactgcc cggtcgtttt ctagtgcctg gagtaaattg atcctgccaa
    12001 acaagcctcc cggtaagagg attgactgct cgcacggaga aaaacgtttg gaagacttga
    12061 ggagggcgat ctgaggcagg tattacgaca gcaggtttgg gagcaatcac cgccttcact
    12121 ttactcggtc cctcttcgtt cactttgagc aagttcaatt gcccttccca gagaaatctt
    12181 cctgtctccg catcatatac tctcagcata aacccagact ttccctgact gtcggcaccg
    12241 attcctccgg cgaaaatacg ccccttgctc ccatcgcttt cagcggcgcc ctcttccttc
    12301 acgttcacgt caaatgaatc ctctgaaaga atggcgcctg tctgaacatc ataggttcgg
    12361 accgttatga gggacgatcc tgctgcctga aaaccaaatc ctgccgctag taccgacgaa
    12421 tggtcggctg gcctttgtac cactgggtca gcgatggccc cgcccctatg gccccgagcc
    12481 ggaaagtcat acacttccgc caaagcaagg cccggcaggc aactcaccgc taccatcaag
    12541 cacagcagca ggggtaacga tcgcccgatg gcaagagagc gctgcgaggt gactgttgcg
    12601 ggccaccatg ctctggctcc ccgatgttga actcgtacgt gagatgtgta atgggccacg
    12661 tgtgcctccc taatggaggc ggattttcac gtgaatacgg atctagggta aatgactcaa
    12721 cggacctggt ggtcccctcg aaggatgggg aaggtagccg tcattgacct tgcccagcgt
    12781 accccgagga tcgatcatta tctttgatga tgacccggca ctaagatatg ggcggaatct
    12841 gatagcttgc gagagggata tgccaccgtt atagtaccgc tatgctccat gcgcgtccca
    12901 tcgtcgtcct gttgagtgtt ctcattgtcc ttgagggtat tctctttgga gttgaatcag
    12961 gctcccctct ctcgacgatc aaagacggca tcttagtcgg gtttctattc gttttacccg
    13021 cgctgctgct cgggggactg atcttcatcc gtcagccgtg ggccgtgatg ggagcggtca
    13081 tatacagcac tattgccctc gcactcgacc tcgccacggt cgttcaggaa gccagccaag
    13141 gatctcctcg cctggttgtc ctcatccttg tcttagcaag cagtctagtc aatttcctaa
    13201 ttatgattat gggaggacgg tgcatgctca cttatcagcc cagtcaacgg cctgcagaaa
    13261 gccatcagtc cgaatatcga tcttcttcct cgtcgtaatt cacctaccct ccagcacccc
    13321 acatcgcaat tcctctgctg gcggagaccc gcactgaggc caagtcctga catggcaaga
    13381 ttttggcaaa ggatccagct tgcacgcgct taccaagcat tcttccggct cccgttgatg
    13441 ggaagagggt gcggttctac ttgaccatga ttatgcgcgg cgagcaaagc acggataggc
    13501 tgaagggaga gcatcggaca gggaaaagag gcaaacaggg ggaattggcg cccttagggt
    13561 gcgtgaagat tacgtcttga aaagattctg acaccaacgc acggagccaa gaacctcctc
    13621 gtagcgttcg aaattcaccg ccttgaggaa cgtgatggcg acatattcgt cgttcatttc
    13681 cgtctgctca gcgaaccctg ccttgaggag agcagggcgt ttcttggata cagcaggacc
    13741 cagaaaatac ttagcctgct tggcgacttc atcggttccc aaatcttccg tcgtcccgtc
    13801 acacatcaaa ctctttacat catccatgga gattccatgc tgacaaagga actgaccgtc
    13861 agacctcagt tctaagatcc atccatcatc ccctaaatca agaacgaggg ggccgcctgg
    13921 ctccagttcg tagaattggg gaatactggt gcgtagcttt gcacgagccg cctcccaggc
    13981 tggaagtgcc accgtactca tgcgcgcgac cgccggggtt ggggactggg atcttccgct
    14041 tccaggcgag cacgcagact tgcaagccga gccgtgtttt cggtcaattt cgggagagca
    14101 tatttacgat ccattcgcac tacttgctcc agtaaatcta cagcagcttg taactgtccg
    14161 agatcttcat aacactgggc caagacgtac cgcgccccgc cggcccgcag ttcgtctcga
    14221 ctgcgttcag caatggattg acttgtttga caacaggcaa tcgcatcgtc gtatcgcttt
    14281 tggattgcga aagtccgccc catcatccgc caggcatcag ccacgccgcc ttgattattc
    14341 agccgacgca tcaggaccag cgactgttca tagtagcgca gtgcgtcatc gcactgtccg
    14401 gtttctcggg ctaccaagcc gaggtcggaa aacagcacag ccttgccgag ttcatcatgt
    14461 actcgggtca taatgtcgag ggcttcgagg taataggctc tggcgcgatc ccactccccc
    14521 gcatctgcac gcagattccc cagattggcc aatgtcgtcc caataccttt gtcgtcgcct
    14581 aacacctttt gtaactccag gacttcctgg tagtagctct gcgccgattc gcggcgtccg
    14641 ctgaccgcgc aaatatttcc gaggtttccc aaagtggcac tcagcgcccg gtggtcaccc
    14701 gtcaatcgat cacattccaa ggcttttgca tagcaagcat aggcatccgt gtaatgccct
    14761 cgagcaaagt gctcgttgcc ctggcgattc agttcttcgg acagtccgtt tcgaagcggc
    14821 atgatccttt acgcctggag cacctgctcc actgcctgtt tggctccgaa tacaatgcta
    14881 gccccatccc ccacaagaat cgagtcgaag ttatatttca acaaccggcg tagcccttcc
    14941 ttggccttcg caacatcccc atatcgctca gagggcaaca gactaagtgc ccccgctggc
    15001 tttccaatca aggcatcccc gacaatcaac acgcccttcc cctgctgaat atagagggcc
    15061 gactcccctg gtgacttctg atccttgagc tgtatcgccc aaatgcctcc aggcaacaac
    15121 tcgccgtctt tataggtttt cgttggtttc acatccatct gggacgcatc agcctcgggt
    15181 atctgtaatt ggcaacgaaa ctccgcctgg taggcgaccg cctcacggag atgatcacga
    15241 ttcgtcacaa taatgtaatc cagcgcccct tgccttcgga tcagcgtact tgcttcggcc
    15301 gtcatgggag ggggatcgat aacgatccgg tgttcgccca ctgtcagaaa cagtccgtta
    15361 aaatcaagcc gcttttcgtc ggagaaccag gaccattgcc aaatgccggg gagtaactgc
    15421 ttcacgcgtt tcgcctcatc tgcagggttt acaaagttgc cacagcgtcc tgcagagttt
    15481 tcgtgacctt cgtgcggata ccggcttcgg tcggaagatc gatgatatcg tcctctgaca
    15541 cagtaatgaa cttacgattt gcaccttttg tcagagagat caggaacatg ctattggtag
    15601 gcttcgtcgg aatcaccacc tccacgcctt ggtcgatgcc cttgacgact tccagaaaca
    15661 tcaatttacc ctcttcccat tcgtccatgg atcctctttc tcccgctaca tgggacctga
    15721 accggcaggc gcagaagcca ataatttctc gacctcctga acaatgacct cggcgcctgc
    15781 tagctccata ttgccgaccc tctgccatct aatcacgcca cgttgatcga ttacatacac
    15841 gttcggaata aattttccgc cgccatagag tttgtccgtc accttattgg gatcgagcag
    15901 atacggatag gtgactttta cggggaacgc gctcagaaat tcaccgacgt cccgcttgga
    15961 gttgcccgat gaattaatac caaccacggc aacattctta ccggccagca cctcatgaac
    16021 cttttgcaga ttggttcctt gcatcataca ggggtcacaa atgtggaaca gacctaggac
    16081 gaccaccttt ccctttaact gctcaagaga aacggcatct cccgtaattg acgagagtgc
    16141 gaacgcgggc gccggctctc ccaccttgaa gaatccagca gccatggcaa tatgagctgc
    16201 ccaaaggggc aacagcacca gtgcagttac gatgaagacc cgtttcattc gcgcctcctt
    16261 ccgcaaggcc agccagcggg aaaagccact gcctttcctc gctgatgcac agcataatcc
    16321 ctcatgaatg accatgctgg catcctagca cgcgaatttt ttcgggagca accacttacc
    16381 caggaaaggg cgcaggctga ctaaacaact gcctgactga ggaaggaccg agacgatcaa
    16441 gaactctgca accagcccac aaccatgtgc cgtacacgaa cggggacgat ttctttcggc
    16501 acgcttcgaa gaagtggcct catacatgcc gacattagcc gaagctgtct ttggaaccga
    16561 aaccacggaa ggggacgatg tatcacctct gcgtcaactc gacagagaat gaaacctaat
    16621 ttccatcgcg cccatacgga atctttgacc gtgagagaca cggcgtccgc acaatcttca
    16681 tcaatgccct ggtcgggatg cttgagtaac tgttgaggca ttcttcgcac gagcacaggc
    16741 aggtctgtat ctgattcaat ctcatggctt accgtgcgag gcagcacaat atcgaaaaga
    16801 ttctgcgcca tagcgagacc gagaaggacc atccttctgc atctccattc gcttgcctga
    16861 aacaggattc gactccaatc aagcgccggt ttccgacgca cgaattcagc gatatcgcac
    16921 acccatttca actgcttcca attatgtaac gttccgtgca cacacagaag aatcagcaag
    16981 tcctcaggac agagccccat caccgccttc gtcggtaaac ccaccggctt cagccgaccc
    17041 cacaatgcat gacgatcaag tcggaaattg gagtggtagc cggcaaggcc ccattgcagt
    17101 ttgaccatgg ccattccgtt tctcttaagg aaaacgtgat gaccctcacg aggatcggcc
    17161 tcagcatcat tatcagcccc aagaagttgg tatccgtgcg accaaagaac ttttctggct
    17221 tgagaaactg ctccatgctc aacaatcagc tcaatgtctt cgcactcgcg catgctcaga
    17281 tcgccatacg caacctgagc taatgtaacc ccgtggaagg gaatcgccat gactcccttc
    17341 gcggcaagcg cgtcaagcag cgccacaagt tccttcgcaa gcacggtgtt catcagagtc
    17401 gtagattgat tttgccgccg gtaggcttca tgaatagccg acgggaccgc cgcagggcag
    17461 atggcagcaa gatttcgata taccagcggt gcgacaccat gagccttcga cagttgccac
    17521 aataggtccc aattgattcc gtcacacact aggtctgtga tttcaactcg aacaaattca
    17581 ctcacagcgg ttcgtgcgca gaggacgagc aagcggccct cgtcactcat tgcggagatt
    17641 cctggacgtg gcggcttcga cttgcgaaaa gcctctaccc gacgtgatgg tttccatcga
    17701 gcgatcgtag atcttgtctg ctgtcccatt ggaatcctaa ctcctgctga gcgttttacc
    17761 cgaagaatag tgaggaccta cggcggatat gcgacgtcgg cgcgcacaat aactcatgat
    17821 tgaccggttc gcttgcacat tcagatggat ccagctgctc tatggatagt catcgttttt
    17881 caatacggag aaatccatca tcctgcagct ggacgagtac atcgagcaat tcagattggg
    17941 cctgcgtagc tgtcacatca aatgtttcgg aaatggtgga gagaatccgt gcaaccgatt
    18001 gagtgccggt acattgcagc cataccgcgg atcccaaggc attcaatcga tggaaatggc
    18061 ccgtgcgcac attaaacaat aggctttcgc cgccctgatt tgtgattcgc acatcagaat
    18121 tttgatgcgg aaacatttgt gaaaaatcga ttgtgcgttc acttaaaaca ggtactgtag
    18181 cgggcataga gaacctcctg actcagaggg ggcaacacat cgaccagtgc aaaggttgcg
    18241 ggttcatcca tgacgcgaat ttgggaatct agtgcgccga acccggatgt agcatgccga
    18301 tgcggcatgt aggcaaaggt agccgtagca gggcggtttc tctattccca gtgaggttgg
    18361 tgcaacatct ctttggaggg gaacacagag cttttatggc agtccgatag agagggacga
    18421 caatgcccct tcctttgagc tgatgagaac cgggatcttt ggagagactc tttggcccgt
    18481 aggcacattg gtctcgtgag accagtcaat aacccacagc ggacccaatg cgatggaaaa
    18541 ggtattcggg aagggaaagc ccagtgcgaa ggatgacgat cgacggacca aacgtcagcg
    18601 ctgctgtaat tacttgcgaa aaggaatcag acccgatgaa ttcaccttca tgaacccggg
    18661 agtgctgctc tatgcatgcg cataaggcta ctgtgacctc aggggcgagc gtaacacgcg
    18721 acaagatttt taccgtcagc ctggcggctc gaacaacccg agttgaagtt cctcggctcg
    18781 ggtaaaagaa ataggatatc gttcagtaaa gcaggcattg caatattggc taggtgtccc
    18841 aggcgctgcc ttgaccatgc catcgagact caaataggcg agactatcag cggtaatata
    18901 tttccgtatt tcgtcggtgg tatgactcga ggcaatcaac tctttctttg tcggcgtatc
    18961 aatgccatag aagcacgggg acacgatcgg aggagaacta atccgcatgt gcacttcttt
    19021 ggccccagca tggcgcagca ttttgacgat tttccgactc gtcgtcccgc gcaccaacga
    19081 atcatccacc acaacgacac gctttcctgc aaggacttct ggaacagcat tgagtttgac
    19141 tttgaccccg aaatggcgaa tcgattgctc cggttcgatg aacgtacgcc ccacatagtg
    19201 attccgaatg agcccgcttt caaatggaac gcctgaacct tcggaatacc ctaacgccgc
    19261 cggcactccc gaatctggca cgggaatcac aatatccgcg tccacagctg attcctgggc
    19321 taattgccgg ccgaaggctt ttcggatcga atagaccgcg ctcccgccaa aaatacgact
    19381 atcggggcgc gaaaaataga catattcgaa cacacacata gcaggctgag tcggcggaaa
    19441 aggcttataa ctcgtcacgc cccgatgatc caggaccacc agctctcccg gttcgatttc
    19501 ccgcacatat tccgcgtcga gcaaatcaaa tgcgcagctt tctgaagcga caatccaggc
    19561 atcgcgaaag cgccccaaac agagcggacg gaatccatgc ggatcgcgag ccgcgatgac
    19621 accctgatcg gtcatgagca ccacggaaaa tgcgccgcga acctgagtga gtgaatcaat
    19681 cacccggtca agcagcgtat ccgctcgtga gtgcgcaatc aggtggatga tgacttccgt
    19741 atcggatgtc gattgaaaaa tggcgccata ggcttccaat tcgctgcgaa gcatggtggc
    19801 attgatgagg tttccattat gcgcaaccgc caagttccca aacgcaaagt tgacgctcaa
    19861 gggctgcaca ttcttcaggc cagcgccgcc cgctgtggaa tagcggttgt gtccgatggc
    19921 catggcaccg ggaagacgag ctaacgcctg ttgcgagaag atatcggcca catggccctg
    19981 ccccttctcg acataaaatt gctccccatc gttggagaca atgccggagg cttcctgccc
    20041 gcggtgttgg agcgcgtaga gaccgagata ggcgagattg gcggcttctt tgtgcccgta
    20101 aatgccaaag accgcacact cgtcgtggaa ttgatcggaa gcaatgagag gtaattcttt
    20161 ggccatgacg tctctgctct agtcctgacc cagcgcccgt ggtattgcca aggcccagcg
    20221 ttcctgaacg cttgtcacct cgagatcgat cgtgcacccc gcgacacgct gatcaccgtc
    20281 aactcgaatc accaaccggc tgccgccgac gacgccgatg cgtgacgcag gcacgccggc
    20341 attcctcgcg gcactcaaca cgttgtccac ctgttcctgc tttactgata gtacgatccg
    20401 cgattggctt tctccaaaga gcaaggcatc gcgccgcaaa ccatcaagcg gcaattgtac
    20461 cacagcaccg acgtgcccat tgggacccga gacgcaacat tcggccaggg ctacggctaa
    20521 tcccccatcg gagcaatcgt gtgccgattg aaccaagccc tctcgaatga gtccaatcgt
    20581 acaggcctgc accgctcgct catcctcgag attcagcaac ggcggtgatc cttgttcgcg
    20641 atgatgcaca atcttgaggt actccgttcc cccaagatcc tcacgtgttc gacccagcaa
    20701 gatgatgacg tcgccggctt gcttaaacca ctgcgtggcc gtacggtcgg ctgcctcgat
    20761 caatcccacc atcccgatca tgggtgttgg atagatcgac aggtcgttgg tctcgttgta
    20821 caaactgaca ttcccgctga cgatgggcac gctcaaggcc tcacaggcgt ccttgaggcc
    20881 ttcgatggcc agcacgaact gccacatgac ttccgggcgc tgcggattgc cgaaattgag
    20941 gcagtcggtg acaccgatcg gttctgcccc cgaacaggcg agattacgtg cacactccgc
    21001 aattgcaatc ttggcacctt catagggatt caacaaacaa tagcgtccat tacaatcgac
    21061 ggacaatgcc aaggccttgt tggtgccttt caccctcagc acagctgcat cagatccggg
    21121 ccgcaccatc gtgttcgtcc gcaccatatg atcgtattgt tcgtagaccc agcgcttact
    21181 ggcaatcgtc ggtgcgccta agagttcaag cagagttgca ttcgcgtcct tcacatccgg
    21241 caatgcgtca taattcaacg actgcaacat ttcctgatag gccggtggcg cactgggtcg
    21301 atcatagcgt gggccgtcgt ccgccagggc cttggcggga atttccgcca cgatctgccc
    21361 attctctttc aacacaacct tgccggtatc cgtgacgcgc ccgatgaccg ccacatccag
    21421 atcccactta cggcaaatct tgatgacttc atcctcgcgg ccggctttcg caaccatcaa
    21481 catgcgttct tgtgattcgg acagcatgat ttcgtacggg gtcatgccgg gctcgcgacg
    21541 cggcacatcc gccaattcca attccacgcc ggtgccttcc cgcgaagcca tttcgcaggc
    21601 cgaactggtc aaacctgccg ctcccatgtc ctgaatcccg accaaacagt ccccggccat
    21661 taactcgagg caggcctcca gcagcagctt ctccgtaaac ggatcgccga cctgcacagt
    21721 cgggcgcttt tgggcagcct gttcatcgaa agaatcggac gccatggtcg cgccgtggat
    21781 cccgtcccgc cccgtctttg agccgaaata gatgacggga ttcccgactc ccgccgcttt
    21841 gcccagaaaa atcttatcct tcctggcaat ccccaggcag aagacattga ccaacggatt
    21901 gagcgcatag atgtcattaa acacgatctc accgccgacc gtcggcaccc ccatgcaatt
    21961 gccataaccg gcgatgcctg acaccacgcc tttcagaaga tggcgagtgt tcgcattgtc
    22021 caggccgccg aatcgcagcg agttcaacag agcgatcggc ctggcgccca tcgtgaaaat
    22081 atcgcgaaga attcccccga cgccggtcgc cgcgccctgg tagggttcga tgaaggaggg
    22141 atggttgtga gactccatct tgaagaccgc acagaggccg tcgccgatat cgacagcccc
    22201 ggcattctcg cccggcccct ggacgacgcg cggaccggtc gtcggtaatt ttttcaaatg
    22261 gatgcgggag ctcttgtagg agcaatgttc gctccacata gccgagaaca tgcccagttc
    22321 ggtccagttc ggctcccggc cgaggatttc caggatcttc ttatattcct cctcgctcag
    22381 cttgtgctgc tcaaggatgg cttgggtaat gaccaaagat ttcatgtctt gcacattctc
    22441 tatcgtggat gagaaccggt cgatccggcg ctcctattca ttcgccatgc cttcacacgc
    22501 cgactaatct ggatggctgt tcagacttgc cgaacgcgct cagcatggag aggaaaatca
    22561 gccgtccgtc ttcgttaccc agcagcgttt cagcgcttcg ttcgggatgc ggcatcatcc
    22621 ccaacacatt cccgtcagcg ttcatgatcc cggcgatatt gtcgagcgag ccgttgggat
    22681 ttgcctcggg cgtgatcttg ccctctgccg tacaatatcg aaagatcact tgcgcattgg
    22741 ccttgatgcc gccaagcgtc accggatcgg tataatagtt gccgtctgca tgtgcgatgg
    22801 gaatcttcag cacctgaccg gactcgcagc gattggtgaa acgagtggcg gcgttctcca
    22861 ccttcacata cacatctttg cagatgaaat tcagggaggt attcctcaac atcacaccgg
    22921 gtaacagacc ggcttcgaga agaatttgga agccgttgca aatgccgatg accagcccac
    22981 cgtctcgcgc gaatgtttta accgcgccca tgacggggga gaatctggcg atcgcgcccg
    23041 tcctgagata gtccccatag gaaaaccctc ccggcaagac gacggcatcc aaccctgcgg
    23101 gcaaggtgtc cttgtgccag atcatcttca cagactggcc aagcacgtct ttaaagatgt
    23161 actcgcaatc gtgatcgcaa ttgctgccgg gaaacaccac cacgccgatg ttcatgtcac
    23221 tcatcctctt gcggccagct gaccggagcc ggtcgtctga tgcgctcgcg acggcagccc
    23281 gtctgcatct tcattcggaa cgagcctgag ctcagcgtta ccagccgccg cgtcactgca
    23341 gctcataccg atattcttcg atgaccgtat tggccagcag tttctcacac atctgcttga
    23401 cctgcgcatc ggccttggcc gaatctgttt cattcacatc cacttccatg tacttgccca
    23461 cccgcacatt tgccgcattc ttgaacccga gcgagtccaa ggcatgctcg atcgctttcc
    23521 cctggggatc taatatcccc tgcttcagcg tgacatgaat tttggctttc attgtacttt
    23581 ccctacgcgc tgcgtctgcg cggttttgtt cacatacttg cgaatccaga aaatcacccc
    23641 gatcgttccc agtcccgcca ttgacaagag aataaacgcc cagcgccagg gcgattcatc
    23701 cagatgatac gccatcagcg caaccgtggc agcccacacc aaaatcgcca gcaccaaccc
    23761 gtaatctaaa aaaaaccgca gaaacctatt catcgtgtcg cgtcccgttt ctcgacatcc
    23821 ctcggggacg atatgcctgg gactgttgcg tttgtcgaag gagggacttc atcgctccgt
    23881 attgcagagg gatggccgtt ctcgtgagtt ccctactcac agacccgctt caagacttct
    23941 tgataggcct cttcgatctt gcccagatcc ttccgaaacc gatccttgtc catcgattct
    24001 ttcgtggcct gatcccagaa ccggcaggtg tcgggagaga tctcatcggc gagaatgagt
    24061 cgattgtgaa agacgccgaa ttccagttta aaatctacca acagcatacg tcgctctttg
    24121 aagaagggta acaagacggc attgatcttg tggcccaatt cacgcatctc tcgcagtacg
    24181 gccggtgtgg caacgttcaa gacgcgcaaa tgatcgtcgt tcaccaacgg atcgcccagc
    24241 gcgtcgtcct tgtaatagaa ctcgatgatg gccggttcga tggctgcgcc ttccttgagc
    24301 cccaaacgct tggcgagact ccccgccact acgtttcgga ccacgacttc caccgggacg
    24361 atggtcactt tcttggtgag catctcgcgg tcgctgacgc gctcaatgaa atgggtctga
    24421 atcccctgct gctcgagcag tttgaacagc cgctccgaca ccttattgtt gaccacccct
    24481 ttatcgacga tggtcccgcg cttttgcgca ttaaacgcgg tggcgtcgtc cttgaaatac
    24541 tgcaacacct gatccggccg ttcggtcgtg aaaattttct tcgccttgcc ctcgtagagc
    24601 atcgtgcctg ccggttcgcc agtcatcctc aatcctccaa ctaccgtgcg aacaattcca
    24661 gaatatcgtc cagcggtctg atcgttccca acaatgtggg atgcccaaac cgccggtcat
    24721 ggcgatattc ctttacctgt tcaagcgcgc ggatcaaact gtggaactct tccagcttat
    24781 ccgtctcgaa ataggtgatg aagtcaaagt cgtccaagcc gctggaatga tacagtttcc
    24841 gtttcacggt attgatgtag ggcagcgccg cttgcgtatg ttcctgcatg agcctcgcgc
    24901 ggctatcctg atccagcgcc caccaatcgg catcctttcg gatgggaatg acgatcgcat
    24961 aggacttcgt ccctgtctcc ggcgccggtg actgcaacgc ctgcttcatg gattcgggaa
    25021 acccggctgc gtaagcagcc ggcttggtca tcccatgcaa atacgtcgtc gccaccagat
    25081 ggcgccccaa acgggtgccc aacaacgagg tgagaaactg ttgcgtatca gacaaggcgt
    25141 gggcatggat gcggaacatg aagtcagcat ggtccgaaag cccgcggagc aaatacgact
    25201 cgatgacgat cttctgggag aactgctcga tgagcccctt cacctcagac acggcgatca
    25261 cgcgggcttc gccattgaga tcccaccaat cgtgatccat ctggaacgca gcgaaggtgc
    25321 cgtaaacgcc gggctgggtc agcagggcct cccgctcggt cgcaccgacc ggcgacacgg
    25381 ccgccccgaa caccagggcc accatcagca cgatcctcat tattaacgca gccatcatgc
    25441 acgcctcttg cggcgtcgcg cggctgggat ggcaagggcg ccgaaaaccc ggcgaaacac
    25501 ctgatcgaga tgccgcagat aatacatggg gtcgaaacaa gcggtgatct cgctcggctt
    25561 caaatgagtc gtgatgaacg gatcccggtt gacgagttcc tgaaatccga ccccnnnnnn
    25621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnntcaaat gagtcgtgat gaacggatcc
    25741 cggttgacga gttcctgaaa tccgaccccg cctttccagg ctgtcatggc attgcgctgg
    25801 accgcctcat acgactcctt gcgttgagcg cccttatcga tcaacgcgag caggagccgc
    25861 tgcgagtaga ccagcccccc ggtcaaatcc agattccgct gcatccgttc gggatacacc
    25921 accagattcc tgaccaggtc cgtgacgcgc gccaacatat aatcgaccag gatggtgctg
    25981 tcgggcatga tcactcgctc gaccgaggag tggctgatat cccgctcatg ccacagcgcg
    26041 acattttcca tcgccgccag actgttgctg cgcacgagac gcgcaagacc gcagaggttt
    26101 tccgaggcaa tcggattgcg cttgtgcggc atcgccgagg agcccttctg accctcggaa
    26161 aaatattctt ccgcctccag cacttccgtc cgctgcagat ggcggatttc tgtggcgatt
    26221 ttttcaatgg tggccgccag caacgccaag gcggacgcat aggccgcatg ccgatcgcgc
    26281 tgcacgatct gattcgagac gggatcagaa gccaacccca ttttggcgca gacatattct
    26341 tcgatttccg gcccctgatg ggcaaatgtc cccatcgcgc cggaaagttt gccgacggca
    26401 atgtctttcc tggccgcctc aagacgtgtc cggtgccggc acgcctcttc gtaccagatt
    26461 gccaacttga atccgaacga caccggctcg ccatggatac catgcgaacg gccgaccatc
    26521 accgtatggc gatgctccaa cgcgcgcttt ttcaaaacgg caatcaactc atcaagatct
    26581 tcgaggatga gatcgagcgc ctccgtcatc tgtaccgcca gggacgtatc gacaatgtcc
    26641 gatgaggtga gccccatgtg gagatagcga tgctcgggcc cgacggacgc catgagcgat
    26701 tcgagaaacg cgatcacatc gtgcttcgtc accttttcaa tttctgcgat acgcgccaca
    26761 tcgatcttgg cctttttccg gatctttgcg ctcgtgccac gcgggatctg tccggcccgt
    26821 tcaaaggccg cgcaggcctg cagttcgact tccaaccaaa tctcgtactt gtgtgtgaga
    26881 tcccagatcg cgctcatgcg aggccgggta tatcgctcaa tcatcgccac ctcatgaaac
    26941 caacaccgtg aatcacaaac agcttcaagt tttcagcttc catcgtcttc tcatcgtctg
    27001 acctgtacgg tccaggcgac ctaatcgctc ccgacaaccg gtaattccgg gaacgcgcgt
    27061 ttccgttcca gccgactatc cgatcccagc accttgtcga gaattccatt tacaaacttg
    27121 gaggcttctt catcgccgaa acttttcgcc agctcgatcg cttcattcag cgtcaccttc
    27181 gccggaacct cagggacaaa aagcagttcg aagcagccca ggcgaagaat attccgatcg
    27241 ataatgggca tccggccgac cttccaattg gtggcatggg tgccgatcaa cgcatccagt
    27301 tctttcttat gctctctgac cccggccacg aggcgctcgg cgaagacgcg gagctcatca
    27361 ttcagcggat attgcgtcca aaaatcgtcc agccatgggc cggcctggcc atgaatgtcg
    27421 tattgaaaga gaatctgtac cgcccgttca cgggcttggt gtcgagaggc cataagacaa
    27481 cgccggtcag cgtttcgccc tcgcggccgt tcgtccggct cttcgtggag cgggacccgg
    27541 cggcacgtcc tcgctctctt cttttttgag ttgtcgcatc acgttgacca tttcaatggc
    27601 cgttttggcg gcatcggcgc cacgattgag cttcgccgga tccgcacgtt caatcgcctg
    27661 cgccaccgta tcggtcgtga gcaccccaaa aatcaccggg agattcgatt ccatcgaggc
    27721 ctgcaggata ccccggctta cttcggtact gatgtattca aaatgaggtg tgtcgcctcg
    27781 aatgacggcg cccaggcaga tgactgcgtc gaatcgacca gaccgggcga gttggcgagc
    27841 caccagagga atttcgaacg caccaggcac ccgcacgacc tcaatcgcct cgtccgacgc
    27901 tccggccttg gtcagcgcct tcacgcattc agtgagcagg cggctggtga cgaacttatt
    27961 gaatttgctc gccacgatcc cgacggtcag acccgtcgcg tcttgggagc ccttgcgaag
    28021 cttcatgccg tgcgataccg attcagacgt ttcatggatt gcgcgtgcgc cgaagaaaga
    28081 gggcgatcat acctggaaac gccatcaaat ggctacacgt ttcaggcgca tctcttcctg
    28141 gcgaaggacg tacgaaataa agcgcggcag acgcgtcaga cttttttcaa caggtggccg
    28201 agtttggcct ttttggtgcg gagatatttt tcattatcag cgcgtggagc aatttcaatg
    28261 ggcacacgtt cgaccacctt caacccgtac ccttcaatcc cgacaatctt ccgcggattg
    28321 ttggtgatca ggcggatctt atggagcccg agctggacga ggatctgcgc gccgacccca
    28381 tagtcccgca aatccgcctt gaagccgagt tgaagattgg cctcgaccgt atcactgccg
    28441 gaatcctgaa ggccgtaggc tctgatctta ttcagcaggc cgattccgcg cccctcctgg
    28501 ttgagataga gcaacactcc ccggccgtcc ttctggatga tctccatggc gcgatggagt
    28561 tgctcgcggc aatcacagcg caacgatccc agcacatccg ccgtcaggca tcccgaatgg
    28621 acccggacaa gcatgggcgt gtcggcatcg acctgtccct tcaccaaggc gatgtgagtc
    28681 gccccgtcga tatcattctc gaacgcaatc gcctcaaaat caccgaacgt tgtgggcaag
    28741 aacgcactcg ccgcccgccg cacgaaggtc tctcgatgca tccggtattc gatcaaggct
    28801 ttgatcgtca ccatttttaa tttgtggcgt ttggcgaact tggtcagctc ggccacgcgc
    28861 gccatcgtcc cgtcctcatt cataatttcg caaatgactc cggcgggata gagcccggcc
    28921 agtcgagcca gatccaccga cccttcggtc tgccccgcac ggcggagcac acccccgact
    28981 tgcgccttca gaggaaaaat atggccggga cgcgccagat cagccggaga acaacgggga
    29041 tcgatggcca cgtggatggt cgtcgcgcgg tcggctgccg aaatgcctgt cgtgatacct
    29101 ttcctggcat cgatcgacac cgtgaaggcg gtgccaaagg tggccgtatt ctccgcagcc
    29161 tgcggggcca actgcagttc ctcaacccgt tccggcgtca gggccaagca gatcaaccca
    29221 cgcgcatgct tggccatgaa attgaccgcc tggggcgtga ccttgctggc cgccatcaca
    29281 agatcgcctt cgttctcgcg atcttcatca tcgacgagga tgatgaactt ccccttcttg
    29341 atgtcccgga tggcttcttc gatcgaatta aacggtgtcg ccatagtccc tcaattgtac
    29401 cgaccggcct gcgtgggtgc ccagctaact cttttcaaac catgcctgtc aacgggaaaa
    29461 accttccgca ttcgtggctg atgcgaccgc ccggggtcgc caccgtaagg cggaacccac
    29521 cgtcatggcg gcggcggcac tcaccagcgc caatccgaga aaacccggca cgaacgtccc
    29581 catggcttcc cgcaataatc cgaacccgat cgggacaaaa aatccaccga tcccccctgc
    29641 ggcccccacc aggcctgatg ccagcccgat atccttggga aaccactcgg agacgatttg
    29701 aaagatcacg ccattgccga accccataac ggcaatcgtc accatcagca ggctcgccag
    29761 ccagggcaat aaaggcaacg aagcggcgaa tgccgtgacg gcagcgagca ccataaacac
    29821 acccgccaac gcagggaggc cgccccagcg atccgccaca tacccgccca ccgggcgaat
    29881 caggctgccg gtcaatccgc agagcgcggc aatggccccg ccgacaatcg gatcgctgcc
    29941 gtactgatcg tgcagcagca ccgggagaaa acttgtcagg ccgacaaatc cgccgaacgt
    30001 aatggcatag acgaggcaga gccaatagac agagggcact tgcaccattc cccaggcctg
    30061 ctgccaccag gcatcttctg cgacggagat agtatgcggt tcttcccgca cgacacgagc
    30121 gaacagaccg atggccagca gaattggcag cgccatgatc ccgcaggccc cgtgccatcc
    30181 caactgcccc tcccattgcg gcgccagcag aaggaccaac accgtgccaa tattgccaga
    30241 cgcgaccaat cccaacacca ggccttgatg ggcggccggg tacgctcgac tggccaccgg
    30301 catggccacc gcaaaacttg ctcctccggc acccagaagc aatgcgatgg cgagcagctc
    30361 tacgtactgt gtcccactga gcgccgccca gaggactgcg atcagttgca accccaagac
    30421 ccacagaccg gttcgtttgg ctccagacca gtcgcaggcc cagccggtca caattcgcag
    30481 cagcgcacca ctcagaagcg gaagcgccac caccacactc tgttgcgtcg ccgtcaggtg
    30541 gagctccgcg cccatcggca ctgccagcgc cccgaacagc acccacacca taaaactcac
    30601 agtgagatgc aaccaggcac ctgccaaggt cggccaatgc ccgctacgca gagccgttcc
    30661 caatgttctg acatttccta acgacttcat cttatgcggc cagggtccga gccttacgaa
    30721 tctctttcat catcacgcac tatacgaggc gcgatttcag agacgcaagc aaggccgatg
    30781 cagatcagac gtactcattg tttcccaaca ctcgacatct ggtatagtca gctcctgtat
    30841 gcaaagggtt cgactcgcat gagacagcgc aagccaaagc ataataccga ttctgactcc
    30901 gattcagctg cggagttgga cgaagacgac agccttgaac ccgaggccct ggagccaacg
    30961 gacgaggagg tgacggaaga acatgaggcg gccgagcggc aaccatcgaa ggagtcgccg
    31021 tctgcaccat tgagcacttc cctggtcccc gtcacgaccc tgcaacaata tctgacggaa
    31081 atccgccgct acccctacct cagcaaggaa gaagagttac gcctcttcga ggagtatcag
    31141 cttcgcggaa gccgggatgc ggcgatgaaa ctcattcttg ccaatctgcg ggtctccgtc
    31201 tccatcgctt ccgaatacct gcacacgggc gccgatcata tggacctgat ccaggaagga
    31261 aacgtcggcc tcctgcaggc catcaagaaa ttcgacccga cgaaaaacgt gcgcttttat
    31321 gcctacgcag cctggtggtc cagggcgtat atcctccgct acctcttgaa cacctatcgc
    31381 ctgatcaagg tcggcaccac ccaggatcaa cgcaagctgt tctacaatct gaagaaagaa
    31441 aaggccaagc tcgaacgcga aggcttcgcg ccagacagca agctgctggc cgaccggctg
    31501 aacgtccgtg aacgcgatgt catcgagatg gatcagcggc tgggcagttg ggaattgtcg
    31561 ctggatcaac ccatcggcca ggaacatgac gggacgttga tggacgtgct gcctgcgcat
    31621 gaacagccgg cagacgagca actggcggac acgcagctga aagcactctt tcggcgcaag
    31681 ctggcggaat ttaccaaaac gctcgacgag cgagaggaag acattctccg caaccgcatt
    31741 ctgtccgaaa ctccactcac gctggaggac atgggcgcaa agtacggcat caccaaggaa
    31801 cggaccaggc aactggaggc ccgcatcatc aaacgactgc gtgatttcat caaaaaggat
    31861 gtgaaggact ttgaccgtct ccggatgtaa gaccggggct agcatcagaa tcgtcctcac
    31921 cattctgatg cttacgaccc tcgtcgaatc ggggtgtccg cgcccttccc acgccgcctc
    31981 cctcatcacc caggaaaatg cccggcccgg tcaatccgac tgggttctga ccgatcccgc
    32041 cgatcatgag gtcgagggtt atgcctcggc caccagcatc cagcgcggag aaccgcttcg
    32101 cctctacatt cacagcaccg atccccatgt gacggtcgac atctaccgta tgggatggta
    32161 tggcgggaca ggagctcgat tggtgcgggg aggcatcacg ctgccaggcg ctcgacaacc
    32221 catgccgaca ccggatcccg tgaccggtct catcgaatgt cgatggcaag tctcatacac
    32281 cctgacgaca gagacacatg agaagaacga ctggctcagc ggcgtgtacc tcgcgaaact
    32341 caccggctcg gccagcggca aacagagcta catcattttc gtggtcaggg aagacgatcg
    32401 gccctcggag tttctctttc aatccagcgt caccaccttt caggcctaca acaattgggg
    32461 cgggaaatcg acctatccgt ccaacagccg ggatgagcaa tgggcacgaa aggtctcttt
    32521 taaccggccc tatgccagga gccaacatcc ccagggcgga agcgggattg gggcgggaga
    32581 attcctgacc gcgatgtcga ttcatccaac ccgcgcgctc tcgaccgcgg gctgggagta
    32641 caacatggtg cgttggctag aacgtcacgg atacgacgtg acctatagca ccgacatcga
    32701 cacccatacc cgggcagaat tctggaaggg ccataagacc tggctgtccg tggggcatga
    32761 cgaatactgg tcggctgaga tgcgacgcca tgtcgaggag gctcgagacc acggagtcgg
    32821 cctgggtttt ttttctgcca atacctgcta ctggcagatc agactggagc ccagcctcct
    32881 taccggcgag ccgaatagaa ccatggtgag ctataaagaa gtggcatgga acgaggatcc
    32941 cctggccctg gatggcgatc catcaaacga ccagttgatc accgtccaat ggcgtgaatc
    33001 gccggttcaa cgaccggaac aggcattgct gggcgtcatg tatgggaccg tcccggtcga
    33061 tggagatatt ctcatcacgc agcccgagca tccgctgttc aacggtgtgg atctgccgcc
    33121 cgaccatcgc cttcccggcc tcctgggata cgaaatcgac caggtattcg ccaacggacc
    33181 agccggttta accgtcctgg ctcattcctc ctatccgagg gatggggagg cagtttatgg
    33241 tgacatgacc ctgtatcagg cccagagcgg cgctttcata ttcgctgccg ggacgattca
    33301 atggagctgg ggcctcgacg actataatgc cccgacattg cggaccgccc gatccagtca
    33361 ggcggcgcaa cgaattaccg gcaacatatt gagattgctg gcctcacccg cctccagccc
    33421 ggctcattag cgacaccggg cggcttcact gcgacggccg acgttcggtt ccggtcaggc
    33481 cctacgatgt gcttcagaag acggctgcga ggagatgggc tacgaaattc gtagaatcaa
    33541 caacttgcgc ggcactttcc cattgcatct cgcggaagaa taattttata gtccatccat
    33601 tgacttccct cgtcatagcg ctatctatga ctcgagtttt ctgcaggttg cccttgcagt
    33661 aacacgtcag agctgaattt ccagctttca cacaactgta cattagggcc tcgacgctca
    33721 ttaatctaga aggaggattg ggtatggcta cggaatcgaa ggaaaagaag tccaccgctg
    33781 cgaagaattt ccagccgctc ggtgaccgcc tgttcgtcac ctacaccgag gagatggaac
    33841 ggacatctgg cggaatttat gttcctgact ccgcgaaaga gaagccgcag cggggaatcg
    33901 tgcaggctat cggcaagaaa gttgagaaca tcaaggtcgg cgaccaggtg ttgttcgaca
    33961 agtattccgg cagcaagctg cggatcgaag acgaagagtg cctcatcctc aaggaagaag
    34021 acatcctggg tatcttcacc cactaatctc acgcacccga ctaacgatta ttctgacgat
    34081 taacggagga cgattatggc aaagcaattg ttgtatagcg aagcggcacg ggcagccatc
    34141 ctgagagggg tgaaccagct cgccgatgcc gtgaaggcga cgctcggccc caagggccgg
    34201 aacgcgattt tggacaagaa gttcggcgcc ccgacgatca ccaaggacgg cgtgacggtg
    34261 gcgaaggaag tcgaactcaa gaatccgtac gagaacatgg gcgctcagtt ggttcgcgaa
    34321 gtcgccagca agaccagcga cacggccggt gacggaacca ccaccgccac ggtgttggcc
    34381 caggcgatct accgggaagg cgtcaagaac atcaccgcag gtgccaatcc gatggaaatc
    34441 cagcgcggca tcaacaaggc cgtggaagtc gtgatcggcg agctgaagaa gctcagcaag
    34501 ccctgccaga acaagaccga gatctcccag gtcggcacca tctccgccaa caacgacaag
    34561 accatcggcg acctcatcgc ggaagcgatg gagaaggtcg gcaaggatgg cgtcatcacg
    34621 gtggaagaag ccaagtcgat gaccacctcg ctggacgtcg tcgagggtat gcagttcgat
    34681 cgcggctaca tctcccccta cttcgtgacc aacgccgagc ggatggaagc cgtcatggac
    34741 gagccgctca tcctcatcaa cgaaaagaaa gtcagcagca tgaaggacct cctcccggtc
    34801 ctcgagcagg ttgccaagct cggcaagccg ctcatcatca ttgctgaaga agtcgaaggc
    34861 gaagcgctcg cgaccctcgt ggtcaacaag ctccgcggca ccctcaacgt gtcggccgtg
    34921 aaggcaccgg gcttcggcga tcgccgcaag gcgatgctgg aagacatcgc gatcctcacc
    34981 ggcggccagg tcatctccga agacctcggc ttgaagctcg agaacgtcaa gctgacggat
    35041 ctgggccgcg ccaagcgcgt cacgatcgat aaggataaca ccacgatcgt cgaaggccat
    35101 ggcgacccga agaagatcga aggccgcgtg aagcagatca aggcccagat cgaggaaacc
    35161 acctcggatt acgatcgcga gaagctccag gagcggttgg cgaagatcgt cggcggtgtg
    35221 gccgtcatca acgtcggcgc cgcgaccgag accgaaatga aggaaaagaa ggcgcgcgtc
    35281 gaagacgcgt tgcacgccac caaggcggcc gtcgaagaag gcatcgttcc tggcggaggc
    35341 acggcctatc tgcgctgcct caagggcttg gattccctca aggacttgcc cctggagcag
    35401 aaagtcggcg tcgacatcgt gcgccgctca ctcgaggagc cggttcgtca gatcgcagcc
    35461 aacgcgggtg ccgaaggctc cgtggtggtc ggccgcgtcc gtgaggacaa gaacccgaac
    35521 ggcggctaca acgccgccgc cgacgagtac gtggacatga tcaagaccgg catcatcgat
    35581 ccgaccaagg tgtcgcgctg cgcattgcag aacgccgcca gcgtcgccgg tttgatgctg
    35641 acgaccgaag tcatgatcac ggaattgccg gaagagaaga aagagcctgc cggtggccat
    35701 gctggtcaca accacggcat ggaagggatg tactaaggtt tccgtttctt cttcgctgtc
    35761 gaagaccggt ccggcggtgg ccccgccggg ccggtctctt tttcgagccg agacgggt
//
LOCUS       DAOQPD010000031        35502 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_493_length_35502_cov_22.516913, whole genome shotgun sequence.
ACCESSION   DAOQPD010000031 DAOQPD010000000
VERSION     DAOQPD010000031.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 35502)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 35502)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35502
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_493_length_35502_cov_22.516913"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..986
                     /locus_tag="PK063_09150"
     CDS             <1..986
                     /locus_tag="PK063_09150"
                     /inference="COORDINATES: protein motif:HMM:NF021387.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050043 - lactate racemase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="lactate racemase domain-containing protein"
                     /protein_id="HMZ97258.1"
                     /translation="EKKVGANLSPAVRVMAHDSRGALVDLGMSPGGLPIRINRTVMEC
                     DLKIGVGCIYPHPIAGFSGGAKIVLPAVCGVETTRMMHDYLRGSRTRGGSIHTELRQD
                     MVAVARKAGLDFIANVTLNHRREISGLFAGDVVKAHEEGVRAAQRMYAVPVVSEADIV
                     VADMYPFDTSWQFAQDRGMWPVECAGSQASRVVIAACPLGLGTHELFPVDSPLWSRVA
                     RRLKHFRLADLDRPFEKLGTIMKLLRQKQHHLMVLSPGLEGKDLHTMFPHAQRFGAWP
                     PLRAALVARHGEGPLTVAVYRCAPLLIPAALDLEQEIGVPDPRATVRLTSA"
     gene            1142..2710
                     /locus_tag="PK063_09155"
     CDS             1142..2710
                     /locus_tag="PK063_09155"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024629.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 39 protein"
                     /protein_id="HMZ97259.1"
                     /translation="MRLTDPSPIGQRNEALWGTDLVVAACLFLMVFGSGVVHIQSFPP
                     LFFDEGWTVCVARTWVESGHYGCLLRGEPAPPSLAAHFPVVASVAASFALFGVGVWQT
                     RVVGLLYTFAALLLLYAVARRLFGRSVAIAALALLILVPLKWSIHPLYLGRQVLGEMP
                     LLCFLLAAFVCFLRSAHRPLWLVAAIGCWSLAFMTKAQVAPFLIASFVGTIVILTLRR
                     NWSAVRQLALVLIGSWAGFRFLIEAKNWLLSGHTMAHPSTDGMTEAIALVFVPAIRLE
                     TIQYLFVAWAEYPLGLAYAAWRLHRTPASRDEESVAQTAQIMLLLLAGSWLAWFAFLS
                     AGEPRYALPGLFLSAPFAALFVCEATRGFDVRYLLRTLAELVPGRRVTPQGFKAAVVV
                     LLLAIMGWGAVQERYAFRAREDDRDLFAVTQHLNTTTSPTALIETYDSELFLFLNRPY
                     TYALPKHLVEIIRREQGQAQAVTYDPLQQNPDYLVVGEYGRWAGFYKPLIAQNRVRLV
                     TTIGRYQIYEPVRS"
     gene            2958..3395
                     /locus_tag="PK063_09160"
     CDS             2958..3395
                     /locus_tag="PK063_09160"
                     /inference="COORDINATES: protein motif:HMM:NF012241.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HMZ97260.1"
                     /translation="MTSYHAALVAPIGQDSFDRQIDRLLEDAVSAFGVSGIAWAPASN
                     AWEDDNGFYVQVALPGWEPQDVSLEVAKHVLSIKGERKEQPQPGKTVHVQEIGDGRFM
                     RLFRLPTYIDSEKASAVQKNGLLTVTFPKREEAKSRRIMIEGT"
     gene            complement(4149..5156)
                     /locus_tag="PK063_09165"
     CDS             complement(4149..5156)
                     /locus_tag="PK063_09165"
                     /inference="COORDINATES: protein motif:HMM:NF024109.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HMZ97261.1"
                     /translation="MRMLTWLLGTIVALATIGAVYQIAGMVLDRQHYPPPGQLVDIGG
                     HRLHLFCLGTGSPTVLLEAPAPGWSLYWSTVQPQLARTTRVCAYDRAGLGWSERGPLP
                     RTGQRMAKELHRLLERAGIRGPYILVGHSLGGLIARLYQHDYPQEVVGMVLVDAGHES
                     EMRQAEFRLFANAGKSMLPVIRALTMVGITRLMASYDQLPPLLMRQEEKVSAETRPML
                     RAGWLRTGYYSTLTDESDGLIETLEQVRRSGSLGNLPLIVITATGPVWWPDMPGQVNQ
                     AKFRKMWLELQQGLTTLSTNSRQVFADQSSHFIPFDQPELLTDVVRQLIDRQRSAPYR
                     P"
     gene            complement(5261..5656)
                     /locus_tag="PK063_09170"
     CDS             complement(5261..5656)
                     /locus_tag="PK063_09170"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ97262.1"
                     /translation="MSPATPSEPSGRERREFYRITVLLPMCLQMAGDETEGELIETSV
                     NLSAGGIGVMVTTPYKSGDVLSLTLLLPDQVRFKASIDVLRLDPLPLLGGVYRLHARF
                     VGLPAHDRELLVRYILRFQRDHLQEHYSA"
     gene            5798..7804
                     /locus_tag="PK063_09175"
     CDS             5798..7804
                     /locus_tag="PK063_09175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009267 - cellular response to starvation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation CstA family protein"
                     /protein_id="HMZ97263.1"
                     /translation="MKTALIVLWMLLSILGAVALAHVVGVINPTEKVNGLWLVVAAAC
                     IYVLAYRFYGRWLARKVVQLDDRRLTPAVRLNDGVNFHPTNRVVLFGHHFAAIAGAGP
                     LLGPVLAAQFGFLPGFLWLVIGAVLAGAVQDFIILVASMRRNGRSLPEIAHDELGSIT
                     GTATAVAVLFIVVVALAGLGFAVVNALYHNAWGTFTIAMTIPIGFIMGFYLQKFRPGA
                     VAEVSVLGLVLLVTAVLFGRVVGQSPYAWLFEFEKPALVWLLAGYGFVASVLPGWMLL
                     VPRGYLSTFMKLGVVFLLGLGVILMAPTIEMPRLTAFANGGGPIIPGTLFPFLFITIA
                     CGAVSGFHSLVSSGTTPKMIEQESQAVVGYAAMLLESFVGVMALIAASVLIPGDYLAI
                     NTMLSAETLTAMGFAPSRLAELSQLVEVNVAGRPGGAVSLAVGMASIFSALPGMAGLM
                     AYWYQFALVFEALFILTTIDTGTRVARYLIQEMAGRVYAPFRQMNWWPGVLLSSAFVV
                     GSWAYLIGTGSISTIWPMFGAANQLLGTLALCIATTVLIKMWKSPYLWVTAIPMLFVG
                     GITLAGSYEMFWMFLAKAATLASGQAFALYLDAVLVAVVAILGVVVLSDSMKQWYGYV
                     ILKRPFSSSEVIATAGGGSAGRAQTAIHRHDDRKFTLPHGGGCC"
     gene            7832..8329
                     /locus_tag="PK063_09180"
     CDS             7832..8329
                     /locus_tag="PK063_09180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014448910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HMZ97264.1"
                     /translation="MADQSSFDVVSEVNMQEMKNVVDQATKEIKQRFDFKDSKTELTL
                     KEKEKELVVLSDDEYKLNAVIEIIKSKCVKRGVSLKAFEYGKIEEALGATVRQVIKIQ
                     SGISSEKAKEITKAVKESKLKVQAQIQGEQVRVISKSKDDLQSAIAFLKGKDFGIDLQ
                     FTNYR"
     gene            8476..9498
                     /locus_tag="PK063_09185"
     CDS             8476..9498
                     /locus_tag="PK063_09185"
                     /inference="COORDINATES: protein motif:HMM:NF027232.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97265.1"
                     /translation="MTKFLASMFLLAGLLLGGCGGSDPVVVIQLHPTNPDILYIATND
                     YIYKSRDGGKTWSNLSKGMSYSRVIAMAVDPVYPATIYAGTKGDAVYKSYDGGQRWTS
                     VRTGLDDATISSVVNQFVFDPSDDNHIFLATTMGVFESKNAGERWVKRMEGMKEVLMV
                     VTLGMDPAHPSVMYAGTSGGVYKTNDQGAHWLQVNNGLVPEGMVKTSRALGVTSVQVD
                     PFAPDTVYAATLAGLYKTTDGAVSWVRIGESLQDQMIVAMVLDHAQAGVMYLAGRDGI
                     HRSGDGGKTWIVLNEGLTTTNIRSLAQSAMDPHVLFAGTNGSGLYKSVDGGAHWQAMP
                     SVFPKD"
     gene            complement(9539..10633)
                     /locus_tag="PK063_09190"
     CDS             complement(9539..10633)
                     /locus_tag="PK063_09190"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97266.1"
                     /translation="MIQTSTLHPRHWLASALIGLLLVGLLPAVQAGEFKSDNPLNQPG
                     KIYWCPNRAADKRITATPDAGCTALYDAERDEKKPAALNQDERNDAATKEPLKILDIQ
                     NEASKFTRDYREFIDCCASEWDSLDRIDELLEQSNHILMSVQQKGIYNSAGFGVGSGA
                     SGLGGGPGQSPKLGTFARQWTLSEIVGTVAIARDDLKKLRTRMKGLITRYEKLDSLDY
                     EQRGREERRIEDEREAITHDLRPKRPATSAPTGMDIQDTTIPTRIGGDIENTHLNRSL
                     NPSFGADIGTTVSPYSNVNESLRPRRGEDLRDSVLTDRVGTQTQDTTLPNASGFEINA
                     AENAEQSSSAHIRGVGPSIGDSSLNSQSRR"
     gene            10769..12061
                     /gene="asnS"
                     /locus_tag="PK063_09195"
     CDS             10769..12061
                     /gene="asnS"
                     /locus_tag="PK063_09195"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HMZ97267.1"
                     /translation="MPVIYIDEAATHAGQEVTIRGWLRSRRDKGKLHFLIVRDGTGDI
                     QAVVSKGAVGDEQFAHSAELTQESSVVLTGTLRQDARAPGGYELDVKRLAVLQVAEPF
                     PIQPKEHGTGFLMEHRHLWLRSSRQHAVLRIRHEIIRACRNFFDDRGFTLVDAPIFTP
                     NACEGTTTLFQTQYFDETAYLTQSGQLYSEATAAAFGKVYCFGPTFRAEKSKTRRHLM
                     EFWMVEPEVAFAELPDMMDLAEQFLAHIVAAVLKTRRAELQILERDIAKLERVTAPFP
                     RITYEEAVDILQRKGNPAKRGDDFGADDETILSKEFDRPVIVHRYPAALKAFYMETDP
                     ARPDLALCMDVLAPEGYGEIIGGGQRIHQHEKLLARIREHHLPVEAFQWYLDLRRYGS
                     VPHAGFGMGIERAVAWICGLEHVRETIPFPRMLYRLYP"
     gene            12372..13295
                     /gene="rsmH"
                     /locus_tag="PK063_09200"
     CDS             12372..13295
                     /gene="rsmH"
                     /locus_tag="PK063_09200"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HMZ97268.1"
                     /translation="MDSARGSHEPVLVDEIVFWLQCKPGGVYVDCTLGYAGLATRILH
                     HTAPDGILIGIDRDADALEESRARLQGVMPRVHLRHGNFSQLKTLVAQVGVQHVDGVI
                     FDLGVSSPQLDRPERGFSFRDDGPLDMRMDRSEGRTAADLIREMPERELADVIYQLGE
                     ERYSRRIARAIVEARTQRVIGTTRELAAVVEHAVPASYRHGRIHCATRTFQALRIAVN
                     RELEVIEPALRDAVDLVAPGGRVCAVSFHSLEDRIVKHTFRALANGPDAAVRVLTKKP
                     VIASESERDHNPRSRSAKLRVVERMSKESMQ"
     gene            13292..13624
                     /locus_tag="PK063_09205"
     CDS             13292..13624
                     /locus_tag="PK063_09205"
                     /inference="COORDINATES: protein motif:HMM:NF016860.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HMZ97269.1"
                     /translation="MKAVAFAAVTSLVLLFVWERVDIVRIGYHIERLKAQKVLLERER
                     DELQVKLSGLTAPERIARLASDKLGMLQPEKGQVVVINFEPETPANPVVAEGEIRIAK
                     NMVTRRAR"
     gene            13624..15342
                     /locus_tag="PK063_09210"
     CDS             13624..15342
                     /locus_tag="PK063_09210"
                     /inference="COORDINATES: protein motif:HMM:NF013100.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HMZ97270.1"
                     /translation="MASPSFRGRRILVACGLSGAFILVIVRLVNLQVMQSAELTVKAD
                     RQHQKNVTLEGARGTIYDRNSKVLAMNMDVPSVFGVPASLGNPGVAARNLSPILHVKA
                     TELEKKLKQEKHFVWLARKLEPEQGRRLERLGLDGVGVVMEGRRFYPKGPLLSHVLGF
                     AGMDDRGLEGVELRYEQYLRGEKRAVVLQRDALGRAVFPKGLNEEGAAAGHSLTLTVD
                     EVVQYIAEKELDEAVTRSSAKSGTMIVMDPRSGAVLAMAVSPRFDPNTVGALAPDRWR
                     NRALTDTYEPGSTMKAVIAAAALEEKVMTPGSMIYGENGQFAIANTIIHDHEKAGWMT
                     FAQMIQKSSNIGAAKVGMALGEWRVFDYLKEFGFGDKSGIDLPGETAGLLRGPRQWGK
                     RSLASISMGQEVGVTPLQMVTAISAIANGGVLMKPYVVSEIRNGKGQLVAQNMPQAKR
                     RIISADTARTLTTLLEGVVTHGTGTKAAIPGFRVAGKTGTAQKVDPRTGKYSSTLLVG
                     SFLGYVPAEDPRLAMIVVIDEPRGEGWGGVVAAPVFRRVGEQVLNYLGVAVDEPVKLA
                     MAGLES"
     gene            15344..16846
                     /locus_tag="PK063_09215"
     CDS             15344..16846
                     /locus_tag="PK063_09215"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HMZ97271.1"
                     /translation="MTLDELISPIQGRLGVLERSGDQRVAIDALTDDSRHVQPGALFV
                     AVQGERVDGHEFLDRVVKAGAAAVVVGRHSQVGSTPCIRVQDSRAALGMVGSRFYGDP
                     SAALRMVGVTGTNGKTTTTYVVKTMLEAANRQVGLIGTVAYLVGKESIPASHTTPGAL
                     ELQKLFARMVEKRLDTVVMEVSSHALALDRTAGSEFDVAVFTNLTQDHLDFHLDMERY
                     FQAKRKLFAELGQPDSRKTKKRAIINADDPWGARMREACTVPVWTYGLHQQADIHADE
                     VTLSPAGTSFTLRTPAGTCPIQSRLVGEHNVSNLLAAIGVVLHEGLTLEQVRAAVGAV
                     SNVPGRFERVDAGQDFTVVVDYAHTEDALVRLLTAAQALRTGRIITLFGCGGDRDRTK
                     RPKMGRAAVQYSDVVILTSDNPRTEDPASILSEVEVGVKDALTARSHVRYRMIADRRA
                     AIEAAINEAKAGDMVLIAGKGHEDYQIVGTTKHHFDDREVAREMIQARRS"
     gene            16892..18328
                     /gene="murF"
                     /locus_tag="PK063_09220"
     CDS             16892..18328
                     /gene="murF"
                     /locus_tag="PK063_09220"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: protein motif:HMM:TIGR01143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HMZ97272.1"
                     /translation="MALFTVEEICEVLSAKSPTGLSPQDLKQRIRRVVTDSRLVRKGD
                     LFIAFQGERFDAHTFVPKVFAQGAVCAIVQEDYRLPPMKPRTGAPIVLGVRDTLEAFQ
                     RLATHYRNRFAIPVIAITGSNGKTTTKEMVAHVVAQRWKTLKTEGNLNNRIGVPQTLF
                     QLAPRHQAAVIEMGVDQQGQTTRLCEIARPTVGVITNIGPDHLEFFGSMEGSAQAKAE
                     LLDHLPQDGSVVLNADDEYFDYLAARAQCRVVAFGSSSKAAVRAANVRTDDKGGTLFG
                     LVLPGKTRQTEVRIRTQGQHNVSNALAAAAVGHALGLSGAAIAEGLAKFRPAAMRSQI
                     SSSHGVQVINDCYNANPASMKAAIQLLAQLGRDKRSIAALGDMLELGADTKRMHRDVG
                     AFLAEQGIGHLMACGVLGRELAAGARQAGMPADRITEHPDAQAAATALARMVRQGDVV
                     LVKASRGMRMEQVVDALTGMRRVAKKAC"
     gene            18386..19462
                     /gene="mraY"
                     /locus_tag="PK063_09225"
     CDS             18386..19462
                     /gene="mraY"
                     /locus_tag="PK063_09225"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HMZ97273.1"
                     /translation="MLYNWLYPLHTQFSFLNVFRYQSFRIIYAAVTAFLIAFVMAPWV
                     IRKLQEIKLGQQIRDDGPKRHLAKSGTPTMGGILIIFAVVLSTLLWADMTNRYVWLVV
                     VATVGFGAVGFADDYLKFIKRQSKGLSAAQKFSGQFLVALAIGVFLYTLPSYTTKLSV
                     PFFKFFTPDLGWFYIVFVILVIVGSSNAVNLTDGLDGLAIGPVMIASLAYTIVAYVTG
                     NRVMAEYLLIPYIEGAGEIAIFTGAILGSSLGFLWFNTYPASVFMGDVGSLPLGAALG
                     TVAVISKHELLLLLVGGVFVIEALSVILQVGSYKLRGKRIFNMAPIHHHFEMKGWDEP
                     KVVVRLWIIAILLALLSLSTLKLR"
     gene            19473..20861
                     /gene="murD"
                     /locus_tag="PK063_09230"
     CDS             19473..20861
                     /gene="murD"
                     /locus_tag="PK063_09230"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: protein motif:HMM:TIGR01087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HMZ97274.1"
                     /translation="MDVKGLQVTVVGLARSGVGAARLLNHLGARVTVADRKEPQELAT
                     ILSQLDQSGIAVKVGAQYESALEGADLVVISPGVPTQLDALNRVRARGVRVIGELELA
                     SRYMTAPIVAVTGTNGKSTTVTLIGKFLKESGKRAFVGGNLGIAASEAALACVQAKPG
                     SPAPYEYVVLETSSFQLETIEQFHPFIASILNVTLDHMDRYNSVEDYVAAKARIFTNQ
                     TAGDYSLFNLDDTRVAALRGNTEAAVVGFSRSGATVSGVAGATVLDGDLIVTTVRGQR
                     EEICRRGDMRLIGLHNVENVMAAVTYGLLCGCSIEAIRAVLRSFPGLEHALEVVRERR
                     GVRYVNDSKGTNVDAVLKALEGIEQPIWLIAGGRDKGGDFSRLEGAIRERVKGLILIG
                     EAAARIQAAMGDFDRCRPAATLRDAVELAAREAQPGEVVLLSPACASFDMFADYQDRG
                     RQFKALVQALPA"
     gene            20897..22114
                     /gene="ftsW"
                     /locus_tag="PK063_09235"
     CDS             20897..22114
                     /gene="ftsW"
                     /locus_tag="PK063_09235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative lipid II flippase FtsW"
                     /protein_id="HMZ97275.1"
                     /translation="MAQHALGTLMLPWSTSTQRASKRVPVDPALLAVTLILALIGVVM
                     VFSASAVVAGNRFHDPWYFLKRQVAWLGVGLLVMHLISRIDYTIWKKLAIPLLCGATL
                     LLVLVLIPSLGNVAKGARRWLHLGPINIQPAEVAKFVAVIYAAAYLTKKQDQITQFAR
                     GLLPPLIVIGLLSGLVLLEPDLGTVVVMGLVVVTLLFLAGARIKHLAILSLCALTGVA
                     GLILTSPYRWKRFLMFLDPTKDPSGAGFQITQSFLAFGSGGPFGVGLGEGKQKLFFLP
                     EAHTDFVLALVGEELGLLGTVTIVLLFGLFVIKGFQIAGRARNAFGKHLAMGITMLIG
                     MQALVNAGVVTGLLPTKGLTLPFVSYGGSSLVANLFGVGILLNISRDRQGGHGGQEGG
                     GSRGARKRGVITE"
     gene            22120..23232
                     /gene="murG"
                     /locus_tag="PK063_09240"
     CDS             22120..23232
                     /gene="murG"
                     /locus_tag="PK063_09240"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: protein motif:HMM:TIGR01133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HMZ97276.1"
                     /translation="MIAAGGTGGHLYPAIAVAREFLRRDPSTRILFVGTTRGIEQKVL
                     AHEGLPLRCITAHPFMGKSPVEMVKALITLPVSLWQSLGVLKQQSADLVFGVGGYTSP
                     AMLVAAFLSRVPGVILEPNAYPGLANKAVAPLVQRIFLAFESTKQFFDRRKTSVVGVP
                     VRQAFLDSSSPETARSETGPKRHLLIFGGSQGAKAINSVVIDALPMLATMNTRLTITH
                     QTGEADHARVAAAYQQAGISAQVVPFLYDMPTALRAADLVVARAGAMTIAELTVCGKP
                     AILIPLPTAIYNHQLRNAEVMAKAGGAVLLPQAELTGAALAHAMTEIFSDQQRLETMS
                     RHSWNMRRSDAAETIVRECYDVIRRRHEASDSARAL"
     gene            23201..24697
                     /gene="murC"
                     /locus_tag="PK063_09245"
     CDS             23201..24697
                     /gene="murC"
                     /locus_tag="PK063_09245"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HMZ97277.1"
                     /translation="MRPATALAPYEQRERERQQQDRNSGQRSFRGQELRRTAMFRKTQ
                     HIHLVGIGGSGMSGIAEVLLTLGYKVSGSDLSQSETTRRLEELGGRIAIGHHEANIGE
                     AQVVVISSAVAATNPEVVAAKARQIPVIPRAEMLAELMRLKFGVAIAGAHGKTTTTSM
                     VANVLAQGGLDPTMVIGGKVNALGSHARLGRGDLLIAEADESDGSFLRLAPTIAAVTN
                     IDREHLDHYGSMERLNDSFLEFVNKVPFYGLAVLCSDDERLRNLLPRVVKRFQTYGLN
                     EYPDHVPDFRATDIALRQWGSEFRVFFRGRNLGPFRLAIPGIHNVSNSLVAIAIGMEL
                     DIPVDLIRKGLAAFSGVERRFHLRGEKAGIMVVDDYGHHPTEVRATIAAAKQGWDRRV
                     VVLFQPHRYSRSRDLMQEFSHAFDQADALFMTEIYAAGEQPIPGVSGAKLVEAVKAAG
                     HPSATFVERKETLAEQVLPTLKSGDLVITLGAGDIWKAGLGILDRLPA"
     gene            24719..25651
                     /gene="murB"
                     /locus_tag="PK063_09250"
     CDS             24719..25651
                     /gene="murB"
                     /locus_tag="PK063_09250"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: protein motif:HMM:NF010480.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HMZ97278.1"
                     /translation="MSRVARKEQSARTRKDWARILEGIRGTITYEASLQSYTSFRIGG
                     PAEVLVEPADVDDLCRVVAQAHAERLPIFVVGGTNLLVRDGGIRGLVLSLRQLKAIRQ
                     EAGSVLYAEGGVGMPTLIGYAIRRSLAGLEWGAGIPGTVAGCVVMNAGTRLGEMKDSV
                     KAVRMVDPKGRVTDIPAAEIPFSYRKAHLPRGIVAAVWLQLKPGAHDQIEKTVKEYLQ
                     YRKNTQPLTLPSAGCVFKNPPQDSAGRLVDVAGLKGARVGDAQVSEKHANFMVNLGHA
                     RAADVLALIRKVRAGVKKASGVTLELELKVVGQA"
     gene            25661..26659
                     /locus_tag="PK063_09255"
     CDS             25661..26659
                     /locus_tag="PK063_09255"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: protein motif:HMM:NF002378.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HMZ97279.1"
                     /translation="MKGVDVTERKPLTRSKIGVLMGGQSSEREVSLKTGEAVYRSLVR
                     SGYDAVAIDVGPGLSQTLQDQAIEVAFLALHGPGGEDGAIQGFLETLGIPYTGSGVRA
                     SAIGMHKVVTKTELAAQGIPVPRGTVVWRGTAPTLNRILTSCKLKLPIVVKPASQGST
                     IGVTIVRQPSQWKEALKVAHRYDPEAMVEAFIPGHEVTLSLLGTADGSVAGLPAVEIV
                     APDGFYDFSAKYEKGRTQYLCPAPLPAAVSRDIKQLAIRTYQALGCNGAARVDFRITA
                     KGKPYVLEINTVPGMTETSLLPMAAGKAGLSYDALTEQILQSALRRAGTGLFRAVR"
     gene            26662..27531
                     /locus_tag="PK063_09260"
     CDS             26662..27531
                     /locus_tag="PK063_09260"
                     /inference="COORDINATES: protein motif:HMM:NF020067.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HMZ97280.1"
                     /translation="MPLRWRNTRPAKLNPRANARSESGLERRRGGATGGYWTRLGRGL
                     LITLRVIATVTVLVGGCSGLFVLAREIGPLTREWFLVRSVSVNGLHHVTRKEVIGRLA
                     LKPDTALYSINPTWLAERIKTHPWIKDATVVLKPLHEIHIDIVEREPAVVVRTLAENL
                     LTDAEGVLLARLGSSDDPTLPILSGVDGKRLAQGRAEDRRPVQVGAALARMVGQTTGG
                     RPDINVGNLNNLVVEVQGVTFQFSESSMNQQWSRFLKMRPALRDVAFDGEGARANEID
                     LRFADRVIVRGRG"
     gene            27528..28772
                     /gene="ftsA"
                     /locus_tag="PK063_09265"
     CDS             27528..28772
                     /gene="ftsA"
                     /locus_tag="PK063_09265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HMZ97281.1"
                     /translation="MSRVSKRDHILVGLDIGTTKICAIVAEVPEEGPLNIIGVGSCPS
                     RGLRKGVVVNIESTVESIKKAVEEAELMAAVQINSVYTGIAGSHISGENLKGVVALKK
                     QEVTRDDISRAVESARTLAVIPHERRILHVLPREFMVDDQEGVREPLGMSGNRLEVNV
                     HVITGAVTSAQNIIKSVNRAGLDVVDIILQPLASSEAVLSAEERELGVAMVDLGGGTT
                     DLAIFLDGSIRHTAVLPIGGQNLTKDLAIGLLTSQTDAEKIKVQHGIARTELVHGHQM
                     VEVPSVGDRPPRQFTRRDIAEILEPRVEEMFDLVKREIVRAGYEGMLGAGVVITGGTS
                     LLEGMPDAAERGLNLPARRGAPTGIGGLRDIVSNPMHATGVGLLLHARQHADNLEAAG
                     IRHGKGLGKVFDRMRSWMFEFF"
     gene            28825..>29657
                     /gene="ftsZ"
                     /locus_tag="PK063_09270"
     CDS             28825..>29657
                     /gene="ftsZ"
                     /locus_tag="PK063_09270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HMZ97282.1"
                     /translation="MFSFQEEPQSPVRIKVIGVGGAGCNAVNTMITGGLCRVDFVAAN
                     TDVQALERSQASYKIQIGPERTRGLGAGAKPEVGRDAALESKDEIRESLVGADMVFVT
                     AGMGGGTGTGAAPIVASIARELGILTVAVVTKPFQYEGHRRMSHAEEGIRDLGRHVDT
                     LLIIPNQRLLGIVDKATPLLDAFKVADDVLRQAIQGIADVITTTGLVNVDFADVRTIM
                     AHTGRAVMGMGIGRGANRAQEAAQKAICSPLLEEGSVEGARGVLLNITGGPNMSLHEV
                     E"
     assembly_gap    29658..29757
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            29944..30681
                     /gene="pgeF"
                     /locus_tag="PK063_09275"
     CDS             29944..30681
                     /gene="pgeF"
                     /locus_tag="PK063_09275"
                     /inference="COORDINATES: protein motif:HMM:TIGR00726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HMZ97283.1"
                     /translation="MASEFITLPSFATHADGAEHFFGTRLSAIPVTPGRASAHRTEQQ
                     DHRAPVILSVKQVHGTDALVVDRPVEQGELFEGGWDALVTNQPGLMVTVRTADCVPVL
                     LHDPVRQVVAAIHAGWRGAVAGIVPKTVALLASRFGTVPKDVRMAIGPSAGACCYEVD
                     EPVLTRLRDVFPEWQSVVSPVNPQKAHLNLRAFVRRQAMHEGLEGERIATVEACTICQ
                     PDEFFSYRREGVVKATMVSGIALVSSR"
     gene            30776..31501
                     /locus_tag="PK063_09280"
     CDS             30776..31501
                     /locus_tag="PK063_09280"
                     /inference="COORDINATES: protein motif:HMM:TIGR00044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HMZ97284.1"
                     /translation="MDSELGTIAGRVRAVFDEIHRATVRAGRAPDSVRLLAASKTVTV
                     ERLREAVDAGIRHLGENRLQEALPKIETLDREGVVWHFIGTLQRRKVKSVVGRFETIH
                     SVDSLALAEEIDRQAKAAGLKQRVLLEVNLGGESSKGGFAPAAVAAALPALNQLEQLD
                     IRGLMAIPPPMPTAEDARPYFRQLRELAQALTAQGCRNINMQELSMGMSHDYAVAIEE
                     GATYVRVGTAIFGARSEPYHDHT"
     gene            31488..32294
                     /gene="proC"
                     /locus_tag="PK063_09285"
     CDS             31488..32294
                     /gene="proC"
                     /locus_tag="PK063_09285"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HMZ97285.1"
                     /translation="MITRNIAVLGGGQMAEALIGGLLASKVSEPQFICATDPVSARRD
                     LLKSRFGIQVGEDNAKAVAGADLVLLAVKPQVLPAVLQDVSSALRGKLVVSIAAGVTT
                     AWIQERVSAARGIVRAMPNTPALVREGVTALAYAADLAADDVAAVRALFEAVGSVVSV
                     EERLMDAVTGLSGSGPAYVFVAIEALADGGVKMGLPRATAQLLAAQTVLGAARMVLER
                     GQHPAQLKDQVASPGGTTIAGLHQLEIGGMRGCLMAAVEAATKRSQELGR"
     gene            32294..32590
                     /locus_tag="PK063_09290"
     CDS             32294..32590
                     /locus_tag="PK063_09290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HMZ97286.1"
                     /translation="MFVVSNVLQGTATVLDTVLWLYMWVIIARALISWVNPDPWNPIV
                     QFLERATEPVLTPIRRLIGWRMGMDLSPMIAILILVFLQYAVVQSLRDIAVRMH"
     gene            32612..33124
                     /locus_tag="PK063_09295"
     CDS             32612..33124
                     /locus_tag="PK063_09295"
                     /inference="COORDINATES: protein motif:HMM:NF016959.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HMZ97287.1"
                     /translation="MKITPIDIQQMVFQVKFRGFDRDEVNRFLEELALTVENLNRENS
                     LLREKLTTTEQQVADLRRTEATLSNTLVSAQTLAEDVKRSAQREADLIVKEAELKASE
                     IIRQARGSLTEMQRGVADLQKQRLMMVERFRSTLRSFERMLEVEESDAYQAEGASVEG
                     KLAGESSPAR"
     gene            33243..34367
                     /locus_tag="PK063_09300"
     CDS             33243..34367
                     /locus_tag="PK063_09300"
                     /inference="COORDINATES: protein motif:HMM:NF012371.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HMZ97288.1"
                     /translation="MNDPIQSALQAAVDDGTFPGAVLAVRLRGEIVFESAVGRLSRQG
                     SEEAVTDHTCYDLASLTKVLATTTALALLIQRGRLKVDDRIDGILNELRDSAIGAATV
                     RQLLTHSSGLPGWRPLYERIAAIEATQPGFMGSPAACEAVTGYIAKEELIYERGSRSL
                     YSDLGFMLLGFAVERLSGEPLDQFCSGQIYEPLGARPLAYARRGPLSALSIHHDAECI
                     IAPTEEDPWRKRMLCGEVHDENAYALGGVAGHAGLFGTARAVLAVSQAWMDGRRKKRG
                     LLEPEIVRTFTTNRQGVPNSSWALGWDTPSVRSSSGTRFSSESFGHLGFTGTSLWIDP
                     VKELEVVLLSNRVHPTRRNEQIRVFRPHIHDVICRELLRN"
     gene            complement(34364..34684)
                     /locus_tag="PK063_09305"
     CDS             complement(34364..34684)
                     /locus_tag="PK063_09305"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97289.1"
                     /translation="MSGLPLLFKKEGLIERHQVEGIDPSDRYFNRAVLVNRVAAGYTG
                     KMTYEAYAVEGTPHSTTSAAVKAVVDKLQSVGFTRMRTRLNFKGNRYLAEKETWTDYP
                     DLSA"
     gene            34861..35397
                     /locus_tag="PK063_09310"
     CDS             34861..35397
                     /locus_tag="PK063_09310"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: protein motif:HMM:NF013250.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HMZ97290.1"
                     /translation="MNVPNSLTMLRILLIPVYVGLLNYEQFDYALAVLFIAGLTDALD
                     GIIARVADQRTRLGEVLDPLADKLMLTTGFITLSVMHLVPLWLTILVASRDLMLMLGA
                     AVAHFTHTQVDISPTVLGKGTTLIQLATLVAVVFFASRRLDLSTLDPLLYLMGGVTLT
                     SGLHYLSRGYVRITSSQT"
BASE COUNT         6821 a         9484 c        11510 g         7587 t
ORIGIN      
        1 tagagaaaaa ggtcggcgcc aacctctcgc cggccgtgcg agtcatggcg cacgacagcc
       61 ggggagccct cgtggattta ggcatgtcgc ccggcgggtt gccgattcgg atcaaccgca
      121 ccgtcatgga atgtgatctg aagatcggag tggggtgcat ctatcctcat ccgatcgccg
      181 ggttctcggg cggcgcaaaa attgtgctcc ctgccgtctg cggtgtggag accacgagga
      241 tgatgcacga ctacttgcgt ggttcacgca cacgaggcgg ttcgatccat acagagctgc
      301 ggcaggatat ggtggcagtg gccaggaagg ccggcctcga ttttattgcc aatgtcacgc
      361 tcaaccaccg tcgcgaaatt agcggcttgt ttgccggtga tgtggtcaag gcccatgagg
      421 aaggggttcg tgcggcacag cggatgtatg ccgtgccggt agtgtctgag gcggatattg
      481 tcgtggcaga tatgtatccg ttcgatacca gctggcagtt cgcccaggac cgcggcatgt
      541 ggccggtgga atgcgccggg tcgcaggcat cccgcgtggt tattgccgcc tgtcctttgg
      601 ggctggggac gcatgaattg tttccggtcg acagtccgct ctggtcccgc gtggcgagac
      661 gtctcaaaca ttttcgcttg gctgatttgg atcgtccgtt cgaaaaactg ggcaccatca
      721 tgaaactgct tcgtcaaaag caacatcact tgatggtgtt gtcgcccggt ctggagggaa
      781 aggatttaca cacgatgttc cctcatgcac agcgattcgg agcgtggccg ccattgcggg
      841 ccgcgttagt ggcgcgccat ggcgaggggc ctttgacggt ggcagtctat cgatgtgcac
      901 cgcttctcat tccagctgca ttggatctgg agcaggagat tggcgtgccg gatccacgtg
      961 ccactgtgcg actgacttcg gcctgaaggc gaggaccgga gggtgtcctg tcctgcaatg
     1021 attcgacgat tggtttatgg gtgaattgtc atctgctatg ccaacgacct cacctcatcc
     1081 attgctcccc cacgacgacg atgatgcgcc ttccggaaca accgggtctg gggatacccg
     1141 agtgcgattg actgatccgt ctccaatcgg ccagcgcaat gaggctttgt ggggcacaga
     1201 cctcgtggtg gctgcatgtt tgtttctaat ggtcttcggc agcggggtcg tccatatcca
     1261 gagtttccct ccactgtttt ttgacgaagg gtggaccgtc tgtgtcgcgc ggacatgggt
     1321 cgagtcaggt cactacggct gtctgctccg gggagaaccg gctccgcctt cattggcggc
     1381 gcatttccct gtcgtggcgt cggtcgcggc gagttttgcc ctgttcggtg tcggagtgtg
     1441 gcagacgagg gtggtggggc tgctgtacac cttcgcggcg ttgctgctgc tctatgcggt
     1501 agctcgtcgc ctctttggac gatcggtcgc aattgccgcc ctggcactgc tgatcctcgt
     1561 gccgctgaaa tggtcgatcc atcccctgta tctggggcgc caggtgctgg gcgagatgcc
     1621 gttactctgt tttctgttgg ctgccttcgt ctgctttctc cgaagcgcgc atcggcctct
     1681 ctggctggtc gctgcaattg ggtgctggtc gttggccttc atgactaagg cgcaggtggc
     1741 cccatttctg atcgcctctt tcgtggggac catcgtcatt ctcactcttc gcaggaactg
     1801 gtcggctgtg cgccaactgg cccttgtttt gatcggttca tgggccggat ttcggttctt
     1861 gatcgaagcc aagaactggc tgttaagcgg gcacacgatg gcgcatccct ccaccgatgg
     1921 aatgacagaa gccattgcct tggtattcgt gccggccatc cgcctggaga cgatccagta
     1981 cctgttcgtg gcatgggctg aatatccgtt gggactggcc tatgccgcct ggcggcttca
     2041 tcgaacgcct gcttcccgcg atgaggagtc cgtggcacag acggcgcaga tcatgctgtt
     2101 gctgctggca gggagttggc tggcctggtt tgcgtttctg agcgccggag aaccgcgtta
     2161 cgctttgccc ggattatttc tttcggcgcc gtttgcagcc ttgtttgttt gcgaggccac
     2221 cagaggattc gatgtgcggt atctgttaag gactctggct gaactcgtgc cgggtcggcg
     2281 ggtgacccct cagggattca aggccgccgt cgtggttctg ctcctggcga tcatggggtg
     2341 gggcgccgtg caggaacggt atgcctttcg agcgagagag gacgatcgcg acctgtttgc
     2401 ggtgacgcag catctgaaca cgacgacctc accgacggcg ttgatcgaaa cctatgacag
     2461 cgagttgttc ctctttttga atcgtcccta cacctacgcc ttgcccaagc atctggttga
     2521 gattatccgg cgtgaacagg gacaggcgca ggcagtcacg tatgaccctc tgcaacagaa
     2581 cccggactat ctcgtagtcg gcgaatatgg ccgatgggca ggattctaca agccgttgat
     2641 tgcgcaaaat cgtgtgcggc tcgtgacgac catcggacgc tatcagatct acgaaccggt
     2701 gcgttcctag cgcgaccgta tccccctcgg tccttttccc ttcttctgta gccgtgaaat
     2761 tgcccccttg acttcatggg agacgggatt attttttcat cgttgctaat gcgtaaccgg
     2821 atggacggga cacagtgccc ggtctggagg gcaatggcgg caggtgaatg ccccgcttct
     2881 gcttcggcca gcattccatc caaacccact cacatcaacc attacactga cctctcagga
     2941 gagaggagga ggacggtatg accagttatc atgcagcatt ggtagcacct atcgggcaag
     3001 actccttcga ccggcaaatc gatcggttac tggaggatgc ggtaagcgcg ttcggcgtaa
     3061 gcggaatagc ctgggctccg gccagtaatg cttgggaaga tgacaacggg ttctacgtac
     3121 aggtcgcgct ccccggttgg gagccgcaag acgtctcgct cgaagtggct aagcatgtac
     3181 tctcgatcaa gggcgagcgc aaggaacagc ctcaaccggg taagaccgtt catgtgcaag
     3241 agatcggtga cgggcggttt atgcggctct tccgattgcc gacgtatatt gattccgaga
     3301 aggcttcggc tgtgcaaaag aatggcttgc tgaccgtgac gtttcccaag cgggaagaag
     3361 caaagagtcg gcggattatg attgaaggga cctaaacact cccatccgtc ttgcgcagaa
     3421 ggcatgatga agcgaaggga tcctcagacg gttcccctcc cgccttcctc cgaataaccg
     3481 gttgttcccg gaggcctcgc tgattcccac gatcggcgag gcctctactc tcacgccgga
     3541 agccatcatg gctaggtagt ttgacctgcc gcagaagaga tgtgcggcat tgtgaaatgc
     3601 tcaaggagaa gacctatgaa ctacagaaat ttcttgaagc gttggcggtg cataggtagc
     3661 cgctcggaat tgggtacgca tgggttgcag ggcgcgatgt cactggcctc cctacgcggg
     3721 tggtggcgga ggcgccgggc ccaggagcgg caggagcgaa gagaagatca tcaggatcgt
     3781 cccgtgaccc cgtggtcgca cggcctattt taagtgtggg cgccctgaga gcctgctttg
     3841 tgatcccaag atgactatct ggaacagaaa ggaggtgaac acgatgatgg atttgagttc
     3901 ggttcttgat gccggactaa cggtggcggg tgcgatcgcg gtgctcttga tgggactctg
     3961 gatgctgtct tctgagtcca gcaccgtgtc tacctcccag cagccggcgg ttccgatgag
     4021 agcatatagg gataacgtcc agctgcctaa ggctgcgtga ttattcacag gccacgctgt
     4081 atgccttgga caagaggcgt aatgaagtct tccccgggaa tctcgctgat ctgctgggga
     4141 agagcccctc agggacggta cggggcgctg cgctgccggt cgatcagttg acgaacgaca
     4201 tcggtgagaa gttccggctg gtcaaaagga ataaagtggc tgctctggtc ggcgaatacc
     4261 tgccggctgt ttgtcgacag ggtggtcagt ccctgttgca gttctaacca cattttcctg
     4321 aacttggcct ggttcacctg tcccggcatg tccggccacc agactgggcc agtggcggtg
     4381 atcacgatca acgggagatt gccgagcgaa ccgctgcggc gcacctgctc cagcgtttca
     4441 atcaatccgt cactctcatc cgtcagcgtg gaatagtagc cggtccgtag ccagccggcg
     4501 cgcagcatcg ggcgagtctc ggccgatacc ttctcttcct gtctcatcaa gagcggcggc
     4561 agctggtcat aggaggccat cagccttgtg atgcctacca ttgtcagggc gcgaatgacg
     4621 ggcagcatgg atttgccggc gttggcgaac aatcgaaatt ctgcctgacg catttccgat
     4681 tcatgacccg catccaccag caccatgccg acgacttctt ggggatagtc atgttggtag
     4741 agcctggcga tcaggccgcc gagcgaatgt cctaccagaa tataaggccc ccggatgccg
     4801 gctcgttcga gcagacgatg gagttctttc gccattcgtt gtcccgtgcg aggcaaggga
     4861 ccgcgctcgc tccagccgag gcccgctcga tcataggcgc agacgcgagt cgttcgggcg
     4921 agctgcggtt gcacggtgct ccaataaagc gaccagccag gtgcaggcgc ctcgaggagt
     4981 accgtcggac tcccggtccc aagacaaaag aggtgcagcc gatgtccccc aatatcgacc
     5041 agttggccgg gtggaggata atgctgccga tccagcacca tgccggcaat ctgatacacg
     5101 gcaccgatag tggcgagtgc aacgattgtc ccgagaagcc acgtgagcat gcgcatgcgg
     5161 gcatcatccc ctgttacagg tcacggaagc aaacggggaa agttcatcca tcaatgtccg
     5221 tggatgtctg agtaccgcgc gagtgagggc attgggacag tcaggcggaa tagtgttcct
     5281 gcagatggtc gcgctgaaaa cgaagaatgt atctgacgag gagttcccgg tcgtgagccg
     5341 gcagcccgac gaagcgagcg tggaggcgat ataccccgcc gaggagcgga agcggatcaa
     5401 gccgtaacac atcgattgac gctttaaagc gaacctgatc tgggaggaga agcgtaagag
     5461 agagcacgtc accggatttg tagggtgtgg tgaccatcac cccgatgccg ccggcactga
     5521 ggttgacgga tgtctcaatc aactcacctt cggtctcgtc tcctgccatc tgaaggcaca
     5581 tgggcagcag gacggtgatg cgataaaact cgcggcgctc tcgcccggat ggctctgaag
     5641 gcgtggcagg cgacatggtt cagaaaaagt ataacaaacc cggtgaacag gttctcgctc
     5701 aaccgtcccg cacttcctgt tcccctacat ggtccggccc ccgcacgtac ggcctcacgt
     5761 cgccccatct ccttgtgttt gtgctactat cccgcgcatg aaaactgcgt taattgtgct
     5821 ctggatgctg ctgtcgattc tgggagctgt ggcgctggct catgtggtcg gtgtcatcaa
     5881 ccccaccgaa aaagtgaacg gtctgtggct ggtggtggcg gcggcctgca tctatgtcct
     5941 ggcctatcgg ttctatggcc ggtggttggc ccggaaagtg gtgcaattgg atgataggcg
     6001 tctaacgccg gccgtgcggt tgaacgacgg ggtgaatttt caccccacca acagagtcgt
     6061 cctgttcggt catcacttcg cggccattgc aggggcaggc cccttgctgg gacctgtgct
     6121 ggcggcgcaa ttcggttttc tccccggctt tctctggctg gtgatcggtg cggttctggc
     6181 cggggccgtg caggatttta ttatcctggt cgcctcgatg cggcgcaacg gccgctcgtt
     6241 accggaaatc gcgcatgatg aactgggctc cataaccggc accgcgacgg cggtggcggt
     6301 cctgtttatt gtggtggttg cgctggcggg gctggggttt gcggtcgtga atgcgctcta
     6361 ccataacgcg tggggcacct ttaccatcgc catgacgatt cccatcgggt tcatcatggg
     6421 attttatctc cagaaatttc gcccgggcgc cgtcgcggaa gtgtcggtgc tcggcctggt
     6481 gttgctcgtg acggcagtgt tattcggccg cgtcgtcgga caatcgccct atgcctggtt
     6541 gtttgaattc gagaagccgg cgctggtctg gctattggcc gggtatggat tcgtagcctc
     6601 ggtcttgccg gggtggatgc tgctggtgcc gcgaggctat ctctcgacct tcatgaaact
     6661 gggtgtggtg tttctgctcg ggcttggcgt gattctcatg gcgccgacca ttgagatgcc
     6721 gcgcctgacc gcatttgcca atggtggggg acccattatt cccgggacgc tgtttccttt
     6781 tttgttcatt acgatcgcgt gtggcgccgt atcgggcttc cattcgctgg tgtcttcggg
     6841 aacgactccc aagatgatcg aacaggagtc gcaggcggtg gtcggatatg cggcgatgtt
     6901 gctggaaagt ttcgtcgggg tgatggcatt gatcgcggcc tcggtgttga tccccggtga
     6961 ttacctggcg atcaacacga tgctctctgc agagacgctg acggcgatgg ggtttgcgcc
     7021 atcgcgccta gcggaattgt cgcagttggt cgaggtgaat gtggcgggcc ggccgggcgg
     7081 ggccgtatcg ctggctgtgg gcatggcctc catcttttca gcgttgccgg gcatggccgg
     7141 cttgatggcc tattggtatc agttcgcgct ggtcttcgag gcgcttttca tcctgacgac
     7201 gattgatacc ggaacacgtg tcgcgcggta tctgattcag gaaatggccg ggcgtgtgta
     7261 cgcgcctttt cggcaaatga attggtggcc cggcgtgttg ctgagcagtg cttttgtggt
     7321 gggatcctgg gcctatctga tcgggaccgg cagcatctcc accatctggc cgatgttcgg
     7381 tgcggcgaac cagttgctgg gcacgctggc cctctgtatc gccacgacgg tgttgatcaa
     7441 aatgtggaag tcgccgtatc tctgggtgac ggccatcccg atgttgttcg tgggaggcat
     7501 tacgctggcc ggctcctatg agatgttctg gatgtttctg gcgaaggccg cgacgctggc
     7561 gtcggggcag gcgttcgcgc tctatctcga tgccgtgctg gtggccgtgg tggctattct
     7621 aggcgtggtc gtcttgagcg atagcatgaa gcagtggtat gggtatgtca ttctcaaacg
     7681 cccgttcagc agcagtgaag tgatcgcgac cgccggcggc ggatccgcag gccgtgcgca
     7741 gacggccatt caccggcatg atgaccgcaa attcacgctg ccccatggcg gcggttgttg
     7801 ttaggataga gagacgtaga aggaggacat cgtggctgac caatcatcat tcgatgtggt
     7861 gtcggaagtg aatatgcagg aaatgaaaaa cgtcgtcgat caggcgacga aagagatcaa
     7921 gcagcgattc gacttcaagg attccaagac cgagctgacg ctaaaggaaa aagaaaaaga
     7981 actcgtcgtg ctctccgacg atgagtacaa actcaatgcc gtcattgaaa tcatcaagag
     8041 caagtgcgtg aagcgcggcg tctccttgaa ggccttcgag tacggcaaga tcgaggaggc
     8101 gctcggggcg accgttcgtc aagtgatcaa gattcaaagc ggcatttcct cagaaaaggc
     8161 gaaggaaatt accaaggcgg tcaaagaatc caagttgaag gtgcaggcgc aaattcaggg
     8221 tgaacaggtg cgggtgatca gcaagagcaa agacgatctg cagtcggcga tcgcctttct
     8281 caaggggaaa gattttggga ttgatcttca gttcaccaac taccgctagc ctggggatgg
     8341 tgaaacaggt gcccagcttc gttctcgctt cgatcagagg ctcaacgtac aagcacagta
     8401 cgcctcgcct cttccctcgc tgcggcctcg ctgagcgacc tgtttgacca tcccctgtgg
     8461 atccgcggtt caagcatgac caaatttctt gcctctatgt tcctgcttgc cggtctcttg
     8521 ctcggcggat gcggtggcag tgacccggtc gttgtcatcc aactccatcc caccaacccc
     8581 gacattctgt acatcgccac caacgactac atttacaaat cgcgtgacgg cggcaagacg
     8641 tggagcaatc tctcgaaggg gatgagttac tcgcgtgtga ttgcgatggc ggttgatccc
     8701 gtctatcccg ccacaatcta tgcgggcacg aagggggatg ccgtctacaa aagttatgac
     8761 ggcggccagc gctggacctc ggtccggacc ggattggatg atgcgacgat atcgtccgtc
     8821 gtgaatcaat ttgtcttcga tccctcagac gataaccaca tcttcctggc gacgacgatg
     8881 ggtgtgttcg aatccaagaa tgccggggag cggtgggtca agaggatgga gggcatgaag
     8941 gaagtgttga tggtcgtgac gctaggcatg gaccccgcgc atccctccgt aatgtatgcg
     9001 ggaaccagtg gaggcgtgta caagacgaat gaccaagggg cgcattggct acaggtgaac
     9061 aacgggttgg tgccggaagg tatggtgaag acgtcgcgtg cgctcggtgt gacgtcggtg
     9121 caagtcgatc ctttcgcgcc cgacacggtc tacgcggcga cgctggccgg cctgtataaa
     9181 accacggatg gcgcagtgtc ctgggtgcgc atcggtgagt cattacagga tcagatgatt
     9241 gtggcaatgg tgctggatca tgcgcaggcc ggcgtaatgt atctggccgg gcgggatggt
     9301 attcaccgga gcggcgatgg cggcaagacc tggatagtgc tgaatgaagg cctgacaacc
     9361 accaacatcc gttcattggc ccagagtgcc atggatccac acgtgctctt cgcgggcacg
     9421 aacggcagcg ggctctacaa gagtgtggat ggcggcgccc attggcaggc gatgccgtcg
     9481 gtatttccaa aggactagta ggtggtgtcg ctaagctgga ggcggttgga aagcgaggct
     9541 atcggcgcga ttggctgttc aaggaagagt caccgatgga tggaccgact cctcgaatgt
     9601 gcgcagagga ggactgctcg gcattctcgg ccgcattgat ctcaaagcct gatgcattcg
     9661 gcaaggtcgt gtcttgcgtc tgagtaccga cacgatccgt taacacgcta tccctaagat
     9721 cttcccctct gcgtggacgg agcgattcgt tcacattgct gtagggcgag accgtggtgc
     9781 cgatgtccgc gccgaagctc ggattgagtg aacggtttaa atgcgtgttc tcgatgtcgc
     9841 cgccgatcct ggtcgggatg gtggtgtcct ggatgtccat gccggttggc gcggaggttg
     9901 ccggtcgttt tggtcgaaga tcgtgcgtaa tcgcctcgcg ttcatcttca atgcgtcgtt
     9961 cttctctccc gcgctgttcg taatcaagtg agtcgagttt ttcatatcgc gtgatgaggc
    10021 ccttcatccg agtcctgagt tttttgaggt catctctcgc gatggcgaca gtgccgacaa
    10081 tttcgctgag cgtccattgc cgggcaaagg tgccgagttt gggagactgg ccagggccgc
    10141 cgcccaaacc gctcgcgccg cttcccacgc cgaaccccgc gctgttatag atgccttttt
    10201 gttgaaccga catcaaaatg tgattggact gttcgagaag ttcgtcgatg cgatcgaggg
    10261 aatcccattc gctcgcgcag caatcgataa attcacggta gtcgcgggtg aacttcgagg
    10321 cttcattttg aatatcgagg atcttgagcg gttcttttgt tgcggcatcg ttgcgctcgt
    10381 cttggttgag tgcggcgggc tttttctcat cccgctctgc atcgtacagc gcagtgcaac
    10441 ccgcatcagg ggtggcggta atgcgtttgt cggcagcgcg attcggacac caatagattt
    10501 ttccgggctg attgagcgga ttgtctgact tgaattctcc cgcctgaacc gcaggcagga
    10561 gtcccaccag caggagcccg atgagcgctg acgcgagcca atgccgaggg tgtagcgtac
    10621 ttgtctgtat catggttttg atgatgcccc ccgagagaca ttgtgtcaat caaaggggag
    10681 aattgtgatg cgcttgaaaa gcccgaggcc gttcgttacc ctcccgcata atcgaagtct
    10741 ctcacgttca tagccagggg gaatgcccat gcccgtgatc tatatcgacg aagctgcgac
    10801 ccatgcaggt caggaagtca cgattcgcgg atggctccgc agtcgacgcg acaagggaaa
    10861 acttcacttt ctcattgtgc gggacgggac gggcgatata caggcagtcg tgagcaaagg
    10921 cgcagtcgga gacgagcagt ttgcccattc agccgagctc acgcaggagt cgagcgtggt
    10981 gctgaccggc acgttgcggc aggatgcgcg cgcaccgggc gggtacgagc ttgatgtgaa
    11041 gcgcctcgct gtcttgcagg tggcggagcc atttcccatt cagcccaaag agcacggtac
    11101 aggattttta atggaacatc ggcatctctg gctgcgctcc agtcgccagc atgccgtgct
    11161 gcgcattcgt cacgagatta ttcgcgcctg ccggaatttt ttcgatgatc gcgggttcac
    11221 actggtcgat gcgccgattt ttacgccgaa tgcctgcgag ggcactacga cactgtttca
    11281 gacgcaatat tttgatgaga cggcgtacct gacgcagagc ggccagctct atagcgaagc
    11341 cactgccgcc gcctttggaa aggtctattg ttttggtccg acatttcgcg cggagaagtc
    11401 caagacgcgc cggcatctga tggaattctg gatggtggag cccgaagtgg ctttcgccga
    11461 actgcccgac atgatggatc tcgccgagca gtttttggcg catatcgtcg cggctgtgct
    11521 gaagacgcgt cgtgccgaat tgcagatctt ggagcgggat atcgcgaagc tggagcgcgt
    11581 gacggcgccg ttcccccgca ttacgtatga ggaagccgtg gacattcttc agcggaaagg
    11641 aaatcccgcc aaacgaggag atgattttgg cgcggacgat gaaaccattc tatcgaaaga
    11701 attcgaccgc cccgtcatcg tgcatcgata tccggctgcg ctcaaagcct tctatatgga
    11761 gaccgatccg gctcgccctg atcttgccct gtgcatggat gtgttggcgc ccgaggggta
    11821 tggcgaaatc atcggcggcg ggcaacgcat tcaccagcac gagaaattgt tggcgcggat
    11881 acgcgagcac catctcccgg tcgaagcgtt tcaatggtat ctcgatctgc gtcgctacgg
    11941 ctcggttcca catgccggat tcggaatggg aatcgagcgc gcggtggcgt ggatttgcgg
    12001 cctcgaacat gtgcgggaga cgattccttt ccccagaatg ttgtaccggt tatatccata
    12061 ggttttcccc atccttccca tcggctgatt cctcctgcgc tcaccgaaat gctgccattc
    12121 catctgtctg attttttgga cgggtctcgc gtttcacaac cattttcatg ccgcaattaa
    12181 tcgaagggtg ggatagtttc ccacaggttt gtccacaaat gtggataact ttgctgccaa
    12241 attgcggcct gcaaacgatg ggtcaaaagc gaacaatatt cttgataaat tggagcaaaa
    12301 tctgttgaca gctgttttgg tgggtgtata ctccagccaa cgtgtggtga aaagtgggtg
    12361 gaagtgggtg tatggattct gctcgcggtt cccatgagcc ggttttagtc gacgaaatcg
    12421 tattctggct gcagtgcaaa ccaggtggag tttacgtgga ctgcactctt ggatatgcag
    12481 ggctcgctac ccggatcctt catcacaccg ctccagatgg cattctcatt gggatcgatc
    12541 gcgatgcgga tgcgctggaa gaatcccgcg cgcgcctgca aggcgtcatg ccccgagtac
    12601 atcttcggca tggaaatttt tcgcaactca aaacactcgt ggcgcaggtc ggggtccagc
    12661 atgtggatgg tgtgattttc gatctcggtg tgtcctcgcc gcaactcgat cggccggagc
    12721 gcggattcag ttttcgtgac gatggcccat tggacatgcg catggatcgg agcgaaggac
    12781 gcacggcagc cgaccttata cgagagatgc ctgaacgtga attggcggat gtgatctatc
    12841 aattgggcga ggagcggtat tcgcgcagaa tcgcccgcgc gatcgtggag gcgagaacgc
    12901 aacgggtcat cgggacgacg agggaattag cggcggtggt ggagcatgcc gtgccggctt
    12961 cgtaccggca tgggcgaatc cattgcgcca cgcggacgtt tcaggcgcta cgaatcgcgg
    13021 tgaaccggga attggaggtg atcgaaccgg cgcttcgcga tgccgtcgat ctagtggccc
    13081 ccggaggacg agtctgcgcc gtgtcgttcc attctcttga ggacagaatt gtgaaacata
    13141 cgtttcgggc tttggcgaat ggcccggacg ctgcagtgag ggtgctcaca aaaaaaccgg
    13201 tcatcgcgtc ggagagcgag cgtgaccata acccgcgttc gcgcagcgcc aagttgcgtg
    13261 tcgtggagcg gatgtccaag gagtctatgc aatgaaagcc gtcgcgtttg ccgcggtcac
    13321 gtcgttggtg ttgctcttcg tgtgggaacg ggtggacatc gttcgcatcg gataccacat
    13381 cgagcggctg aaagcgcaaa aagtgctgct cgagcgtgag cgggatgaat tgcaagtcaa
    13441 gctgtcgggg ctcacggcgc ctgaacggat tgcacgcttg gccagcgata aattgggtat
    13501 gttgcaaccg gagaagggcc aggtggtcgt catcaacttt gagccggaaa cgcctgcgaa
    13561 tcctgtcgtc gcagaaggcg aaattcggat tgcgaagaat atggtcaccc ggagagcgcg
    13621 atagtggctt cgccctcctt tcgtggtcgc cggatcctgg tggcctgcgg gttgtctggt
    13681 gcgtttatcc tcgtgattgt ccgcctggtg aaccttcagg tgatgcaatc ggcggagttg
    13741 accgtcaagg ctgaccggca acatcaaaaa aatgtcacgc tggagggggc gcgcggcacc
    13801 atctacgatc ggaacagcaa agtgctggcg atgaacatgg atgtgccgtc tgtgttcggg
    13861 gtgcccgctt cgctcggaaa tccaggagtg gccgcccgca atctctcgcc gatcttgcat
    13921 gtgaaggcaa ccgaactcga aaaaaagttg aagcaggaaa agcatttcgt gtggcttgcc
    13981 agaaagctgg aaccagagca gggacggcgg cttgaacggc ttggcctcga tggcgtcggt
    14041 gtggtgatgg aaggccgtcg gttctacccg aagggcccgc tgctgtcgca tgtgctggga
    14101 tttgccggga tggatgatcg tggcctggaa ggagtggagc tgcgatacga gcagtatctg
    14161 cgcggcgaaa aacgtgccgt ggtgttgcag cgagatgcct tgggtcgcgc ggttttcccc
    14221 aagggattga atgaagaagg cgccgccgcc ggacatagcc tcacgttgac ggtcgacgag
    14281 gtggtgcaat atatcgccga gaaggagctg gatgaggcgg tgacacgatc cagtgccaag
    14341 tccggcacga tgattgtgat ggatccccgg agcggcgccg tgctggctat ggccgtgagt
    14401 ccgcgattcg atcccaatac ggtcggcgcc ctggctcccg accgatggcg taaccgtgcc
    14461 ctgaccgaca cctacgaacc gggctcgacc atgaaggccg tcattgcagc ggcggcgctg
    14521 gaagaaaagg tcatgacccc gggcagtatg atttatggtg aaaacggaca attcgcgatt
    14581 gccaacacga tcatccatga ccatgaaaaa gccggctgga tgacgtttgc ccagatgatt
    14641 caaaaatcga gcaatatcgg cgctgccaag gtcgggatgg cgttgggtga atggcgggtg
    14701 ttcgactatt tgaaggagtt tggcttcgga gataagagcg gcattgatct gccgggtgaa
    14761 acggccggat tgttacgagg gcctcgccaa tggggcaaac gctcgttggc ctccatttcc
    14821 atggggcagg aagtgggtgt cactccattg cagatggtga cggcaatttc ggcgatcgcc
    14881 aatggcggcg ttctcatgaa gccgtatgtt gtctcggaga tccgtaacgg caaagggcaa
    14941 ttggtggcgc agaatatgcc gcaagccaaa cgtcgtatta tttctgccga cacggcgcgg
    15001 acgttgacga cgcttctgga aggagtggtc acccacggaa cagggaccaa ggcagctatc
    15061 cccggttttc gtgtggccgg caagaccggc accgctcaaa aagtcgaccc ccgaaccggc
    15121 aagtactcct ccacgctcct ggtcggatcg tttctcggct atgttccagc ggaagacccg
    15181 cgactggcca tgattgtggt gattgacgaa ccgcgcggcg aaggctgggg tggtgtggtg
    15241 gcggctccgg tgttccggcg ggtcggcgag caggtgctca attatctggg tgtcgcagtc
    15301 gatgaaccgg tcaagttggc gatggcgggg ctggaatcct gatatgacgt tggatgagct
    15361 gatcagtccc attcaggggc gccttggagt gctggagcgg agcggagatc agcgcgtggc
    15421 cattgacgcg ttgaccgatg attcccggca cgtccagccc ggtgcgctct ttgtggccgt
    15481 gcagggagag cgggtcgacg gccacgagtt tctagaccgt gtcgtgaagg cgggggctgc
    15541 ggccgtcgtc gtgggtcgcc acagtcaggt cggatcgacg ccgtgtatcc gtgtgcagga
    15601 ttcccgggcg gcgttgggaa tggtgggaag ccgattttat ggagatcctt ctgctgcgct
    15661 ccgcatggtc ggagtgacgg ggaccaacgg gaagaccacg acgacgtatg tcgtgaaaac
    15721 catgctggag gccgcgaatc ggcaggtcgg tctcatcggc acggtcgcgt acctcgtcgg
    15781 aaaagaatcc attccggcgt cgcataccac ccccggtgcg ttggagttgc agaaattatt
    15841 tgcacgaatg gtcgagaaga ggttggatac ggtcgtcatg gaagtgtcgt ctcacgcctt
    15901 ggcccttgat cgcaccgccg gctcggaatt cgatgtcgcc gtgtttacca acctcacgca
    15961 ggaccatttg gacttccatc tggatatgga acggtacttc caggcgaagc gcaagttgtt
    16021 cgccgagctc ggccagcctg actcgcgcaa gacaaaaaag cgggccatca tcaatgcgga
    16081 tgatccctgg ggtgcacgga tgcgcgaagc ctgcacggtc ccggtgtgga cctatgggtt
    16141 gcatcaacag gccgacatcc atgcggacga ggtgacattg tcgcctgcgg gcaccagttt
    16201 tacgttgcgc accccggccg gtacatgccc gattcagagt cgcctggtcg gagaacacaa
    16261 cgtctcgaac ctgcttgccg cgatcggggt cgtgctccac gaaggattaa cactggagca
    16321 agtccgtgcc gcggtgggcg ctgtctccaa tgtaccgggg cgattcgaac gggttgacgc
    16381 aggacaggac ttcacggtgg tggtggacta tgcgcatacc gaagatgcct tggtccgatt
    16441 attgaccgcg gcccaggcgc ttcgcacggg gcgtatcatt accctctttg gatgtggtgg
    16501 cgaccgggat cgcaccaagc gtcccaagat gggtcgcgct gcggttcagt atagtgacgt
    16561 ggtgatcctg acatcggaca atccgcgcac ggaagacccg gcgtccattc tcagcgaagt
    16621 cgaggtcggg gtgaaggacg cgctgacggc tcgcagtcat gttcgatatc ggatgattgc
    16681 ggatcgacgc gcagcaatcg aggctgccat caacgaggcg aaggccggcg atatggtgtt
    16741 gattgcggga aaaggccacg aggactatca gatcgtgggg acgacgaaac atcacttcga
    16801 cgatcgggaa gtggcgcgtg agatgattca ggcgcgccga tcctgacgct cagcgaggca
    16861 tgacatgcgg gagcatggac atcgtggcgt aatggcgttg tttacagtcg aagaaatttg
    16921 tgaagtgttg agcgccaagt cgccgactgg cttgagtccg caagatttga agcagcggat
    16981 tcgccgggtg gtgaccgatt ctcgtctggt gcgaaaaggc gatctgttca tcgccttcca
    17041 gggagagcga ttcgacgcgc atacgttcgt gccgaaagtc ttcgcgcaag gcgccgtttg
    17101 tgcgatcgtg caggaggact accgccttcc gccgatgaag ccgcgaaccg gcgcaccgat
    17161 tgtgctcggc gtgagggata cgctcgaagc ctttcagcgg ttggcgacgc actatcgcaa
    17221 ccggtttgcc atcccggtga tcgccatcac ggggagcaac gggaagacga cgacgaagga
    17281 gatggtcgct catgtggtcg cacagcggtg gaaaacgctc aagaccgagg gcaatctgaa
    17341 taatcgcatc ggcgtgccgc agacattgtt ccagctggcg ccgcggcatc aggctgcggt
    17401 gatcgaaatg ggcgtcgatc agcaggggca aacgacccgg ctgtgcgaaa tcgcgagacc
    17461 gacggtcggc gtgattacca atatcggacc ggaccatctg gaatttttcg gcagcatgga
    17521 agggtccgcg caagccaagg ccgagttgct cgatcatctg ccgcaagacg ggtcggtggt
    17581 gctgaacgcc gacgatgagt atttcgatta tctggctgcc cgtgctcaat gccgggtggt
    17641 cgcgtttggt tcgtcatcca aggcagccgt tcgtgccgcg aatgtgcgaa ccgatgacaa
    17701 ggggggcacg ctcttcggac tggtgcttcc cggaaagacg cgtcagacgg aggttcgtat
    17761 ccgaacccag gggcaacaca acgtgagtaa tgccctggcg gcggccgccg tgggacatgc
    17821 cttggggctg tccggcgcgg ctatcgccga aggattggcg aagtttcgtc cggccgcgat
    17881 gcgatcacag atcagttctt cgcatggtgt gcaggtcatc aatgattgtt acaacgccaa
    17941 tcccgcgtcc atgaaggccg ccatccagct cctggcgcaa ttggggcgtg acaaacgatc
    18001 gatcgcggct ctgggtgaca tgctggagtt aggggcggat accaaacgca tgcatcggga
    18061 cgtcggagcg tttctcgccg agcaagggat cgggcacctg atggcctgtg gtgtcttggg
    18121 acgggagctg gcggccggtg cacgtcaagc gggcatgccg gctgatcgga ttacagaaca
    18181 tccggatgcc caggccgcag ccacggcttt ggcacggatg gtgcgacagg gcgacgtggt
    18241 gttggtcaag gcgtcgcgcg ggatgcggat ggaacaggtc gtcgacgcgc tgaccggcat
    18301 gcgacgcgtg gcgaaaaagg cctgttagcc acacttaaag gaattttaga atccgccgat
    18361 tttgggcggg caaagaagcc gtaggatgtt atacaactgg ctctatccac ttcatacaca
    18421 gttttcgttc ctgaacgtct ttcgctatca gagtttccgg atcatctacg cagcggtcac
    18481 cgcgtttctc atcgcctttg tgatggcgcc ctgggtcatc cggaaattgc aggagattaa
    18541 actcggccag cagattcgcg acgacgggcc gaagcggcac ttggccaaga gtggaacgcc
    18601 gacgatgggc ggcattctca ttatctttgc ggtcgtgctc tccacgctct tgtgggccga
    18661 catgaccaac cgctacgtgt ggttggtggt ggtggcgacc gtcggcttcg gcgccgtggg
    18721 atttgccgac gactatctga aattcatcaa gcgccaatcc aaaggactgt cggccgcgca
    18781 aaaattttcc ggccagttcc tcgtggcgtt ggccatcggc gtctttctct acaccctccc
    18841 gagctacacg accaaactca gcgtgccctt cttcaagttt tttacgccgg acttgggctg
    18901 gttctacatt gtgttcgtca tccttgtcat cgtcggcagt tccaatgccg tcaatttgac
    18961 ggacgggctc gatgggttgg cgatcggccc cgtcatgatc gcctcactgg cctatacgat
    19021 cgtcgcgtat gtgacaggga atcgggtcat ggccgaatat ttgcttatcc cgtacatcga
    19081 aggcgccgga gaaatcgcca tttttaccgg tgcgatttta ggatcgagtc tgggattcct
    19141 ttggttcaac acgtacccgg cttccgtctt catgggcgac gtggggtcgc ttcccttagg
    19201 cgcggcgctg ggaacggtgg ccgtgatcag caagcatgaa ctgctgctcc tcttggtggg
    19261 cggagtgttc gtcatcgaag ccttgtcggt catcttgcag gttggatcct ataaattgcg
    19321 gggcaagcgc attttcaata tggcgccgat ccatcatcac tttgagatga aaggatggga
    19381 cgagccgaag gtcgtcgtgc gcctgtggat tattgccatt ttgttggcgt tgctcagctt
    19441 gagcacgctc aaattgcggt agacggaatc gtatggacgt caagggtctt caagtcacgg
    19501 tcgttggtct cgccaggagc ggcgtcggcg ctgcgcggct gttgaaccat cttggggcac
    19561 gggtcaccgt ggccgaccgg aaagagccgc aggaactcgc gaccatcctc tcgcagttgg
    19621 atcagtcggg cattgccgtc aaggtgggag cccagtatga atccgccctc gagggcgcgg
    19681 atctggtcgt gatcagcccc ggagtgccga cacagctgga tgcgctcaac cgtgtgcgtg
    19741 ctcgcggggt gcgagtgatc ggcgaactgg aattggcgtc acggtatatg accgcgccga
    19801 tcgtggcggt gaccggaacc aacggaaaaa gcaccacggt gacgttgatc ggcaagtttc
    19861 tgaaggaaag cggaaagcga gccttcgtgg ggggcaatct cggcatcgca gccagtgaag
    19921 cggctctcgc ctgtgtgcag gccaagcccg ggagccctgc gccctatgag tatgtggtct
    19981 tggaaacctc gagctttcag ctggaaacaa ttgagcagtt ccatccattc attgcatcga
    20041 tcctgaacgt gacgctcgac catatggacc gttacaactc ggtagaagat tatgtggcgg
    20101 ccaaggcgag gattttcacg aatcaaacgg ccggtgacta ttccctgttc aatctggacg
    20161 acacgcgagt cgccgcgctg cgcgggaata cagaagctgc ggttgtcggc ttcagccgga
    20221 gtggagccac ggtttccggc gtggcgggcg ccacggtgct ggacggtgat ctgatcgtca
    20281 cgacggtgcg gggacagcgc gaggaaatct gtcgccgggg cgacatgcga ttgatcggac
    20341 tccacaatgt ggagaacgtg atggcggccg tgacctatgg tctgctgtgc ggttgttcca
    20401 tcgaagcgat ccgcgccgta ctgcgatcct ttcccggcct ggagcatgcc ttggaagtgg
    20461 tgcgtgagcg ccggggcgtc cggtacgtga atgattccaa aggcacgaat gtcgatgcgg
    20521 tattgaaagc cctggaaggt atcgaacagc cgatctggtt gatcgccggc ggacgtgata
    20581 aaggcggtga tttctcccgt cttgaaggag cgattcgtga acgggtgaag gggctcattc
    20641 taataggcga agccgcagcc cgcatccaag cggcgatggg tgattttgac cggtgtcgtc
    20701 ctgcagcgac cctccgcgat gccgtggagc ttgctgctcg cgaggcgcag cccggtgagg
    20761 tggtcctact ctcgccggcc tgcgccagtt ttgacatgtt tgcggattat caagaccggg
    20821 gccggcaatt caaggcgctg gtccaggcgc ttccggcgtg agaccgggag tcgcgcggag
    20881 gaacgacaac tgaacgatgg cacagcatgc gctcgggact ctgatgttgc cctggtcgac
    20941 ttcgactcag cgggcgtcca agcgcgtgcc ggtggacccg gcactgttgg cggtcaccct
    21001 gatcctggcc ctgatcggtg tggtgatggt gttcagcgcc agtgccgttg tggcgggcaa
    21061 ccggtttcac gatccgtggt atttcctcaa acggcaggtc gcctggttgg gcgtcggcct
    21121 gctggtcatg catctcatct cacggatcga ctacacaatc tggaagaagc tggcgatccc
    21181 cctgctctgc ggggctacgc tgttgctcgt gttggtgctc attccatcgc tcgggaatgt
    21241 ggccaagggt gcacggcggt ggctccatct ggggccgatc aatattcagc cggccgaggt
    21301 ggcgaaattc gtggccgtca tctatgcggc tgcctatctg accaaaaagc aggatcagat
    21361 tacgcaattc gcgcggggct tgttgccgcc gctgatcgtc attggtttgc tgagcggctt
    21421 ggtgctgctg gaaccggacc tgggcaccgt cgtggtgatg ggactcgtgg tggtgacgtt
    21481 gctgtttctg gccggggcgc ggatcaagca cctggcgatt ctctccttgt gcgccttaac
    21541 tggggtggcc gggctcattt tgacgtcacc gtaccgttgg aaacggtttc tcatgttctt
    21601 ggatcccacg aaggatcctt ccggagcggg ctttcagatc acgcagtcgt ttttagcctt
    21661 cggaagcggt gggccgttcg gagtcggctt gggagagggc aaacagaaat tattcttctt
    21721 gccggaggcg cacacagatt ttgtgctcgc gttggtcggc gaggagttgg ggttgttggg
    21781 caccgtgacg atcgtgttgc tcttcggtct cttcgtgatc aaaggctttc agattgcggg
    21841 ccgggcgagg aatgcattcg gaaaacatct ggcgatgggc atcacgatgt tgatcggcat
    21901 gcaggcgctg gtcaatgcgg gtgtggtcac gggactgtta cccaccaagg ggttgacgct
    21961 ccccttcgtc agttacggcg gctcttcgct ggtagccaat ctgttcggcg ttgggattct
    22021 gttgaatatc tcacgcgacc ggcagggcgg ccatggcggg caagaaggcg gcggatcacg
    22081 gggcgcgcga aagcgcgggg tcatcacgga atgaacatcg tgattgcagc aggaggcaca
    22141 ggggggcatc tgtatccggc catcgccgtg gcgcgtgaat ttttgcggcg agatccatcg
    22201 acccgcatcc tcttcgtcgg gacgacgcgt ggcattgagc aaaaggtgct ggcccatgaa
    22261 gggcttccgt tgcggtgcat cacggcgcat ccgtttatgg gcaagagccc ggttgagatg
    22321 gtgaaagctc tgatcactct gccggtgagt ctttggcaat cgctcggcgt gctgaaacag
    22381 cagagcgccg atctggtgtt cggcgtaggg ggatacacca gcccagccat gctggtggcg
    22441 gcgtttttga gccgagtccc cggcgtgatt ctcgagccca atgcctaccc ggggctggcg
    22501 aataaagccg tcgcgccgct cgtgcagcgc atctttctgg ccttcgagtc cacgaaacaa
    22561 tttttcgatc gacgcaagac gagcgtggtc ggggtgccgg tgaggcaagc cttcttggat
    22621 tcgtcctctc ccgagacggc acggagcgag accggaccga agcggcacct gttgattttc
    22681 ggcggcagtc agggagcgaa ggccatcaac tcggtagtga tcgacgcgtt gcctatgctc
    22741 gccaccatga atacccggtt gaccatcacg caccaaaccg gcgaggcgga tcatgcgcga
    22801 gttgcggcgg cgtatcagca agcaggaatc tctgcgcagg tggtcccgtt tctgtacgac
    22861 atgcccaccg cgcttcgtgc cgcagatctc gtggtggcgc gggccggagc catgacgatt
    22921 gccgaattga ctgtctgcgg gaagcccgcg attctgatcc cgctccccac ggctatttac
    22981 aatcatcagt tgcggaacgc agaagtgatg gcgaaggcag gcggggcagt ccttctgccc
    23041 caggcggaat tgaccggtgc ggctctggcc catgccatga cggaaatttt cagcgatcag
    23101 caacgtttgg agaccatgag ccggcacagc tggaatatgc ggcgcagtga tgcggcggaa
    23161 accattgtgc gtgaatgtta tgacgtcata aggaggcgcc atgaggccag cgacagcgct
    23221 cgcgccctat gaacaacgag agcgggagag acagcaacag gatcggaaca gcggacagcg
    23281 atcatttcga ggacaggagc taaggcggac ggcgatgttc agaaagacac aacatattca
    23341 tctggtgggc atcggcggat ccgggatgag cggcatcgcc gaggtgttgt tgacgctcgg
    23401 atacaaagtc agcgggtcgg acctcagcca gtcggaaacg acgcgccggc ttgaagagct
    23461 gggagggcgc atcgccatcg gccatcatga ggccaatatc ggcgaggcac aagtggtggt
    23521 gatttcctcc gcggtggcgg cgaccaatcc tgaggtggtg gcggcaaaag cgcgtcagat
    23581 tccggtcatt ccgcgcgctg aaatgttggc cgaactgatg cggctgaagt tcggcgtggc
    23641 gatcgccggg gcgcatggca aaaccaccac gacgtcaatg gtggccaatg tgctggcaca
    23701 gggcgggctg gatccgacca tggtgatcgg cggcaaggtg aacgcgctgg gaagccatgc
    23761 ccggttgggg cgaggcgatc tgctcatcgc ggaagccgac gaaagcgacg gctcgtttct
    23821 ccgtctggcg ccgaccatcg ccgccgtcac gaatatcgat cgtgagcatc tggatcatta
    23881 cggcagcatg gagcggctca acgacagttt cctcgaattt gtgaacaagg tcccgttcta
    23941 cggcctggcc gtgctctgct ccgatgacga acggctgcgc aatctgttgc cgcgcgtggt
    24001 gaaacgattc cagacttacg ggctgaacga atatcccgat cacgtgccgg attttcgtgc
    24061 caccgacatc gctttgcggc aatgggggtc cgagttccgg gtgttcttcc ggggacgcaa
    24121 cctggggccg ttccggttgg ccattcccgg aatccacaat gtgtcgaatt cgctggtcgc
    24181 gattgcgatc ggcatggaac tggatattcc ggttgatctc atccggaaag gcctggcagc
    24241 gttcagcggc gtcgaacgcc ggtttcatct gcgcggggaa aaggccggca tcatggtggt
    24301 ggacgattac ggccatcatc cgaccgaagt gcgggccacg attgcggctg cgaagcaggg
    24361 ctgggaccgg cgcgtggtcg tgctctttca acctcaccgc tatagccgct cacgcgattt
    24421 gatgcaggag ttttcccatg cattcgacca agccgatgcg ctctttatga cggagatcta
    24481 tgccgccggc gagcaaccga ttcccggcgt gtccggcgcc aagttggtcg aagcggtgaa
    24541 ggctgcgggc catccttcgg ccaccttcgt cgagcggaag gaaactctgg ccgagcaggt
    24601 actgccgacg ctgaaatcgg gggatctcgt gatcacgctc ggcgcgggag atatttggaa
    24661 ggcgggattg ggcatcctcg atcgattgcc ggcctgaggg cgatgagagg caggaacggt
    24721 gtcacgtgtg gcgcggaaag agcaatcggc gagaacgagg aaagactggg cgcgcatcct
    24781 tgagggaatt cgtggaacga tcacttacga ggcgtcgctg caatcctata cgtcgttccg
    24841 catcggggga ccggccgaag tcctggtgga gccggccgat gtggacgatt tgtgccgggt
    24901 ggtggcgcag gctcacgccg aacgcctccc gattttcgtg gtgggtggga cgaatctgct
    24961 cgttcgtgac gggggaatcc gcggcctcgt gcttagcctc cggcagctca aggccatccg
    25021 ccaggaggcg ggatctgtcc tctatgcgga ggggggcgtg ggcatgccga cgttgatcgg
    25081 gtatgccata cgtcgctcgc tggcagggct ggaatggggc gccggcattc ccggcacggt
    25141 cgccggttgt gtggtgatga acgcggggac gcgcttgggt gaaatgaagg attcggtcaa
    25201 ggccgtgcgc atggtggatc cgaaggggcg ggtgacggac attccggccg ccgagatccc
    25261 gttcagttac cggaaggcac atctgccgcg cgggatcgta gcggcagtgt ggctgcaatt
    25321 gaagcccggc gcgcacgatc agatcgaaaa gaccgtgaaa gagtatttgc agtatcgcaa
    25381 gaacacccag cccttgacgc tccccagcgc cggctgcgtg ttcaagaatc ctccgcagga
    25441 ttccgccggg cgtttagttg acgtcgcggg gctcaagggt gcgcgtgtcg gggatgcgca
    25501 ggtctcagag aagcacgcca atttcatggt gaacctcggg catgcgcgcg cggcggatgt
    25561 gctggccttg atcaggaaag tgcgcgcggg agtgaagaag gcctcgggcg tcacactgga
    25621 attggaattg aaggtggtcg gtcaggcctg aggccgatcg atgaagggag tggatgtgac
    25681 ggaacggaag ccgctgactc gttcgaaaat cggggtgttg atgggggggc agtcctcgga
    25741 acgcgaagtc tccctcaaga caggcgaagc cgtgtaccgg tcgcttgtgc gcagcggtta
    25801 cgatgcggtg gcaatcgacg tgggaccggg gttgtcccag accttgcaag accaggcgat
    25861 cgaggtggcg ttcctggcat tacatggacc aggcggggaa gacggcgcca tccagggatt
    25921 tctggaaacc ctcggtattc cctacacagg atccggcgtg cgcgccagcg ccatcggcat
    25981 gcataaggtg gtgaccaaaa cagagctggc cgcccaaggt attccggtgc cgcgcggcac
    26041 ggtcgtgtgg cgcggcacag cgcccacgtt gaatcgtatc ctgacgagct gcaaattgaa
    26101 gttgccgatc gtcgtgaaac cggcgagcca ggggtcgacc atcggcgtca ccatcgttcg
    26161 ccaaccttcg cagtggaaag aggcactgaa ggtggcccat cgatacgatc cagaagcgat
    26221 ggtcgaggcg tttatccccg ggcacgaagt cacgctgtcg ttgttaggga ctgctgatgg
    26281 gagcgttgcc ggattgcctg ctgtggagat tgtcgcaccg gacggatttt atgatttttc
    26341 ggccaagtac gagaagggcc gcacgcagta tctttgcccg gctccactgc ctgctgcagt
    26401 gagccgcgac atcaagcaat tggccatccg cacgtatcag gctttgggct gcaacggagc
    26461 ggcgcgggtg gattttcgta ttacggccaa aggcaaaccc tatgtgctgg aaatcaacac
    26521 ggtcccggga atgacggaga cgagtctgtt gccaatggcg gcaggcaaag ccggtctgtc
    26581 atacgatgcg ttgacggagc agatcctcca atccgccctt cggcgggctg gaacgggatt
    26641 atttcgagcc gtgaggtaac gatgccgctc aggtggcgga acacgcgacc ggccaaactc
    26701 aatccgcggg cgaatgcccg ttcggaatcg ggcctggaac gtcgtcgtgg cggagcgaca
    26761 ggcgggtatt ggacacggct tgggcgaggc ctgctgatta ccttgcgagt catcgccacg
    26821 gtgacggtcc tggtcggtgg ctgttcggga ctctttgtgc tggcgcgcga aatagggccg
    26881 ctgacgcgcg agtggtttct ggtgcgctcc gtgtcggtga atggtctgca tcacgtgacc
    26941 agaaaagagg tgatcggtcg gctggcgctc aaaccggata ccgcgctcta ttccatcaat
    27001 ccgacgtggt tggcggaacg gatcaagact catccctgga tcaaggatgc gaccgtcgtg
    27061 ctgaagccgt tgcacgaaat ccatatcgac atcgtcgagc gggagccggc ggtggtcgtc
    27121 cgcacgctgg cggaaaattt gttgaccgat gccgaagggg tgttgctggc gcgtctgggg
    27181 tccagcgatg acccgacgct tcccatcctg tcgggggtcg atggcaagcg gttggcacaa
    27241 ggccgggcgg aggatcgccg ccccgtgcag gtaggggcgg ccttggcgcg catggtgggg
    27301 cagaccaccg gcggtcggcc ggacatcaat gtggggaatt tgaataatct ggtggttgag
    27361 gttcaaggtg tcacgtttca gttcagtgaa tcatcgatga atcagcaatg gtctcggttt
    27421 ttgaaaatgc ggcccgcact gcgtgatgtg gcctttgacg gcgagggcgc cagagcgaat
    27481 gagatcgatc ttcgctttgc cgaccgcgtc attgttcggg gaagggggtg agccgagtgt
    27541 ctaagcggga tcatatcctg gtcgggctcg atatcggaac gaccaagatt tgcgccattg
    27601 tcgccgaagt accggaggag ggcccgctga acatcatcgg cgtcggctcc tgtccttcgc
    27661 gcgggcttcg caagggtgtc gtggtcaata tcgagagtac tgtggaatcg atcaagaaag
    27721 cggtcgagga agcggaactc atggcggccg tgcagatcaa ttcggtctac accggcattg
    27781 cgggcagcca catttcggga gagaacctca agggcgtcgt ggcgctcaag aaacaggaag
    27841 tcacgcgcga tgacatcagt cgtgccgtgg agagcgcaag aacgctggcg gtcattcccc
    27901 atgagcggcg cattctgcat gtgttgccgc gcgagttcat ggtcgacgat caggaagggg
    27961 tgcgcgagcc gctgggcatg tcgggcaacc ggctcgaggt caatgtgcat gtcatcacgg
    28021 gggcggtgac ctcggcccag aatatcatca agagcgtgaa ccgggcaggc ctcgacgtgg
    28081 ttgacatcat cctgcagccg ctggcctcca gcgaagcggt gttgagcgcg gaggaacgcg
    28141 agctgggcgt ggccatggtg gacttgggcg gcggcactac cgacctcgcc attttcctcg
    28201 atgggagcat ccggcacacg gcggtccttc ccatcggcgg acagaatctt accaaagatc
    28261 tcgccattgg cttgttgacc tcgcagaccg acgcggaaaa gatcaaagtg caacatggca
    28321 tcgcccgcac cgagctggtc cacgggcatc agatggtcga agtgccctcg gtcggcgacc
    28381 gtccgccgcg gcaattcacg cgtcgcgaca tcgcggaaat tctcgaacct cgcgtcgaag
    28441 aaatgttcga cctcgtcaag cgcgaaatcg tgcgggccgg gtatgaaggc atgctcggcg
    28501 cgggcgttgt gattacgggt ggaacctcgc tcttggaagg catgccggac gcggcggagc
    28561 gcgggctgaa tctgccggcc cgccggggcg cgccgacagg tatcggtgga ttacgggata
    28621 tcgtcagcaa cccgatgcat gcgaccggcg tcgggctgtt actccacgcg cgtcaacatg
    28681 ccgacaactt ggaggctgcc ggcattcgtc acggcaaagg gttgggtaaa gtgtttgatc
    28741 gcatgcgatc gtggatgttc gaatttttct aactgttgcg gacggcttca gaccatccgc
    28801 gccatcgtga agggaggtgc cacaatgttt tcatttcaag aggagccgca atcgcccgtt
    28861 cgcatcaaag tgatcggggt cggaggcgca gggtgcaacg ccgtcaatac gatgatcacc
    28921 ggcggactgt gccgggtcga ctttgtggcg gcaaatactg acgtgcaggc gctcgaacgg
    28981 tcgcaggctt cctataaaat tcaaatcggt ccggagcgca cacgaggcct gggcgcgggt
    29041 gccaagcctg aggtcggtcg cgatgcggcc ctcgaaagca aggatgagat ccgggagagc
    29101 ctggtcgggg ccgacatggt cttcgtcact gccgggatgg gcggtggcac cgggaccggc
    29161 gccgcgccga tcgtggcgag tattgcgcgt gaactgggga ttctcaccgt cgccgtcgtg
    29221 acgaaaccgt ttcaatatga agggcatcgc cggatgagcc acgccgagga aggcattcgc
    29281 gatctcggcc ggcatgtcga cacgctgctg atcatcccga atcaacggtt gctgggcatc
    29341 gtggataagg cgacgccgtt gctggatgcg ttcaaggtcg cggacgatgt gttgcgccag
    29401 gccattcagg gcattgccga tgtcattaca accacgggac tcgtgaacgt cgacttcgcc
    29461 gatgtgcgga ctattatggc ccatacggga cgtgcggtga tgggcatggg catcggccgc
    29521 ggcgccaacc gggcacaaga ggccgcacag aaagccattt gcagcccgtt gctggaagaa
    29581 ggtagcgtgg aaggggctcg cggggtgttg ctcaatatca ccggtgggcc gaatatgtcg
    29641 ctgcatgaag tagaagannn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    29701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnncag
    29761 gatccgatcg gcccatcaag gacatcgatc ggccgacctt cctccggcgc atgggtgaga
    29821 cgcgggaagc ggtggagcga atcgcagttg tcggcgacga tgagtgggat gtgcccacct
    29881 tcctgcgcaa gcaagccgat tgaagatgag tccgttccgg aagacgtaag gtcgcaggag
    29941 tcgatggcgt cagagttcat tacccttccc tcgtttgcaa cccatgccga cggggcagaa
    30001 cactttttcg gcacccggct gtccgccata ccggtcacgc cgggacgtgc ctctgcgcac
    30061 agaacggaac aacaggatca cagagcgccc gtgatccttt ccgtcaagca ggtgcatggg
    30121 accgatgcct tggtcgtcga tcggccggtc gagcaggggg agctgttcga gggaggctgg
    30181 gatgcgctgg tcaccaatca gccgggactg atggtcaccg tgcgaacggc cgactgcgta
    30241 cccgtcctgt tgcatgatcc tgtgcgacag gtcgtggctg ccatccatgc gggctggcgt
    30301 ggcgctgtgg caggcattgt gccgaagact gtcgcgttgc ttgccagccg attcgggacc
    30361 gtgcccaaag acgtgcgcat ggccatcggg ccttccgccg gtgcctgttg ttatgaggtc
    30421 gacgaaccgg ttctgacgcg actcagagac gtcttccctg agtggcagtc ggtcgtatca
    30481 ccggtaaatc ctcagaaagc gcatttgaat ttgcgcgcgt tcgtccggcg tcaagccatg
    30541 catgaagggt tggagggaga acggattgcc acggttgagg cctgcactat ctgtcagccc
    30601 gacgagtttt tcagctatcg ccgggaaggt gtggtgaaag cgacgatggt cagcgggatt
    30661 gccctcgtgt cctcacggta acgggggcgg ctagtcgtca tcctgaatct ccgcgcctgc
    30721 aggtgcccgg gatccatcgg aattgagcga aggcggcaat ctgcaaggcg gcaggatgga
    30781 ttcagagctg ggcacaattg ccggtcgggt tcgagcggtg ttcgacgaga ttcaccgagc
    30841 cacggtccgt gcgggacggg ctccggactc ggtgcggctg ctggcggcat ccaaaaccgt
    30901 caccgtggaa cggttgcggg aggctgtgga tgccggtatt cgacatttgg gtgaaaaccg
    30961 cctgcaggag gcgctcccga aaatcgagac gctggatcgg gaaggggtcg tctggcattt
    31021 catcggcacc ctgcagcgac ggaaagtaaa gtcggtcgtc ggtcggttcg agaccattca
    31081 ctctgtcgac agcctcgccc tggcggaaga gatcgatcgt caggccaagg cagcggggtt
    31141 gaagcaacgg gtgctgctgg aggtgaatct cggaggagaa tccagcaaag gcggttttgc
    31201 ccctgcagca gtggcggcag cccttcccgc tctgaaccaa ttggagcagt tggatattcg
    31261 tggtctcatg gccattcctc cgcccatgcc gactgcggag gacgcgcgtc cctacttccg
    31321 acagcttcgc gaactcgcgc aggcattgac agcgcagggc tgccggaaca ttaatatgca
    31381 ggaactgtcg atgggcatgt cccatgacta cgcggtcgcc attgaagaag gcgcgacgta
    31441 cgtcagagtc ggcaccgcaa ttttcggggc ccggagtgag ccgtatcatg atcacacgta
    31501 acatcgccgt tcttggcggc gggcagatgg ctgaggcatt gattggtggt ctgttggcct
    31561 cgaaggtcag tgagccacag ttcatctgtg ccacagaccc cgtttcggcc cggcgggatc
    31621 tcctcaagtc gcgttttggc attcaggttg gtgaagataa tgccaaggct gtcgcggggg
    31681 cagatctcgt tctcttggct gtgaagcctc aggtgttgcc cgctgtgctc caggacgtga
    31741 gttcagctct cagagggaaa ctcgtggttt cgattgctgc cggtgtcacg acggcgtgga
    31801 ttcaggagcg ggtctcggct gcgagaggca ttgtgcgggc gatgccgaat acgccggcgc
    31861 tggtgcgcga aggggtcacc gcattggcct atgcggctga ccttgccgct gatgatgtgg
    31921 cggcggtgcg ggctctattc gaagcggtgg gctctgtggt ctcggtcgag gaacggctga
    31981 tggacgcggt tactgggttg agcgggagcg gaccggccta tgtgttcgtc gcgatcgagg
    32041 cattggccga cggcggagtc aaaatgggct tgccgcgtgc gaccgcacaa ttgctggcgg
    32101 cgcagacggt gctcggtgcg gcacggatgg ttctggaacg agggcagcat ccggctcagc
    32161 tcaaggatca ggtggcctcc ccagggggca cgaccatcgc gggattgcat caattggaaa
    32221 tcggcggcat gcggggatgt ttgatggcag ccgtcgaggc ggcgacaaaa cgttcacagg
    32281 agttgggacg ctgatgtttg tggtgagcaa tgtgctgcaa gggacggcaa cagtgttgga
    32341 tacggtgttg tggctctaca tgtgggtcat catcgcccgt gccttgatat catgggtgaa
    32401 tccggatccg tggaatccga ttgtccaatt tttggagcgc gcgacggaac cggtcctcac
    32461 accgattcgg cggctgatag gatggcgcat gggcatggat ctttcgccga tgattgcgat
    32521 cctgatcctt gtctttttgc aatatgccgt ggttcaatcc ttgcgggata ttgccgtgcg
    32581 gatgcattaa ctgtcgggca agaggtgtcg catgaaaatc actcccatcg atattcagca
    32641 gatggtgttt caggtcaagt ttcgagggtt tgaccgggat gaagtgaacc gctttctcga
    32701 ggagttggcg ctcaccgtcg aaaatttgaa tcgagagaat agcctccttc gtgaaaaact
    32761 caccaccacc gagcagcagg tggctgactt gcgacgcacc gaagcgacgc tctccaacac
    32821 attagtctcg gcccagacgc tggcggagga cgtcaagcga tccgcccaac gagaggccga
    32881 cttgatcgtg aaggaggccg aactgaaagc gagtgaaata atccggcagg cgcgcggcag
    32941 tctcaccgag atgcaacgcg gcgtggcgga tctgcaaaaa cagcggctca tgatggtgga
    33001 gcgctttcgt tctaccctgc ggtcatttga gcggatgctg gaagttgaag agagcgacgc
    33061 gtatcaagca gagggggctt cggttgaagg gaagctcgcc ggcgaatcca gccctgcgcg
    33121 ttgagtctcc tgcgttcatc gggaattcca cctttgcctg caatcctgaa ccggcggagc
    33181 ggaccgtccg ctcccggcct ctccccgcca gctcagcttc acgctagatc gtacggatgg
    33241 ctatgaacga tccgatacag tcggcgctgc aagccgccgt cgacgacggg acatttccag
    33301 gtgccgttct ggcagtacgc ttgcgcgggg agatcgtctt cgaaagcgcc gtcggccggc
    33361 tgtcccggca agggtcggag gaagccgtca cggatcatac ctgttacgac ctggcgtctc
    33421 tgaccaaagt tctcgcgacg accaccgcgc tcgccttgtt gatccagcgt ggacgcctga
    33481 aggtggacga ccgcattgac gggatcttga atgagttgcg agacagtgcg atcggagccg
    33541 ccacggtgcg gcagttgctc acccacagtt ccggtctgcc gggatggcgc cccttgtacg
    33601 aacgtattgc cgcgatcgag gcgacgcagc cgggattcat gggcagtcca gcggcgtgcg
    33661 aggcggtaac gggctacatc gcgaaggaag agttaattta cgagcggggc tcccgtagct
    33721 tgtatagcga tctgggtttt atgctgttgg gtttcgccgt ggaacggctc tcaggcgaac
    33781 cgctggatca attctgcagc gggcagatct acgagccgct tggcgctcgc ccgttggcct
    33841 atgcgcggcg tgggccccta tcggccttgt ctatccatca cgatgcagaa tgcatcattg
    33901 ctccaacgga ggaggatccc tggcggaagc gcatgctctg tggcgaggtc catgacgaaa
    33961 atgcctatgc tcttggcgga gtcgctggtc acgcggggtt gttcgggact gcccgggccg
    34021 tactggccgt ttctcaagcc tggatggatg gccggcgcaa aaaacgaggc ttattggaac
    34081 ccgagatcgt caggaccttt acgacaaaca ggcagggcgt gccgaactcc agctgggcgc
    34141 ttgggtggga tacgccgtcg gtgcggtcgt cgtcaggaac gcgtttctct tccgagtcgt
    34201 tcggccatct cgggttcacg ggcacgtcat tgtggatcga tccggtcaag gagctggaag
    34261 tggtgctcct ctccaatcgg gttcacccta ccaggcggaa tgaacagatc cgggtcttcc
    34321 gcccgcacat ccacgatgtt atttgccggg aattactgag aaattaagcg gacaaatcgg
    34381 ggtagtcagt ccaggtttct ttttcggcga gatagcgatt gcctttgaag ttcaggcgtg
    34441 tgcgcatccg agtgaaaccc acgctctgca gcttgtcgac gacggctttg acggcggcac
    34501 tggtcgttga atggggggta ccctccacgg cgtaggcttc gtaggtcatt ttgcccgtgt
    34561 atccggccgc gacccggttc accaggacag cccggttaaa atagcgatcg cttggatcga
    34621 tcccctcgac ctgatgccgc tcaattaatc cctctttctt aaagaggagg gggagtccac
    34681 tcatactaaa cctccgtcga tcatctgtag gccgcgactt acgggtcccg attataggga
    34741 cctgccttgt cgagtgcaac cgtcgttgac aaggttccgc aggggtttct atgatgcgcg
    34801 attcctgtgc cgtgatccgg caaccgaaat ggtgtgtccc gtcagtttct tgtgatgaat
    34861 atgaacgttc ccaacagtct gacgatgtta cgcattctgt tgattcccgt gtatgtcggg
    34921 ctgctgaact acgagcaatt cgactatgca ttggcggtcc tgttcatcgc cgggttgacc
    34981 gatgcgctcg acggaatcat cgcccgggtg gcagatcagc gaacgaggct cggggaagtc
    35041 ctcgatccct tggcggacaa actgatgctg accacgggat tcatcaccct ctctgtcatg
    35101 catctcgtgc cgctctggct gacgattctc gtcgccagcc gcgacctcat gctgatgttg
    35161 ggggcggcgg tcgcccactt cactcatacg caggtcgata tctcgccgac ggtgctgggg
    35221 aaaggcacga cattgatcca gctggcgacg ttggtggcgg tcgttttctt tgcctcgcgg
    35281 cggcttgatc tttccacgct cgatccgctt ttgtacctga tgggcggtgt gacgctgacc
    35341 tccggcctgc actacctctc ccgcggatac gtacgcatta cctccagcca gacatagcgc
    35401 gccttcactg aggtgccgct cctagggcct tttttcaggg cttcgtcttt cgtgcatttg
    35461 tttgacagtt tttaggtcgt cttatagact tcgatcatag tt
//
LOCUS       DAOQPD010000032        35453 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_495_length_35453_cov_23.125120, whole genome shotgun sequence.
ACCESSION   DAOQPD010000032 DAOQPD010000000
VERSION     DAOQPD010000032.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 35453)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 35453)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35453
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_495_length_35453_cov_23.125120"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1294
                     /locus_tag="PK063_09315"
     CDS             <1..1294
                     /locus_tag="PK063_09315"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HMZ97291.1"
                     /translation="TIPGTVMALCRLNVPSLMIYGGSIMPGQFQGHDVTIQDVFEAVG
                     KHASGKMTNAELKDLEDHACPGPGACGGQFTANTMAIAFEFLGMSPMGRNGVPAMDVR
                     KDDVAFECGKMVMDLLKKDIRPKQIITRRSIENAIAAVATTGGSTNAVLHLLAVAREM
                     GVRLTIDDFDKINRKVPLLADLKPGGHFTAADLYAAGGTTLVAKRLIDAKILHPDQIT
                     VSGRTIGEEAKAATEKPDQQVLRPLSKPIKPTGGLVILKGNLAPEGCVVKVAGHSILH
                     FSGPAKVYEREEDAFKAVQAGKIKAGDVVVIRYEGPSGGPGMREMLGVTAAIVGAGLG
                     DSVALLTDGRFSGATHGLMAGHVAPEAIKGGPIAAVKTGDVITFDIVKRRLDVNITQK
                     EMASRLKKVKHPAPRYLSGVMGKYARHVSSASEGAVTS"
     gene            1297..2202
                     /locus_tag="PK063_09320"
     CDS             1297..2202
                     /locus_tag="PK063_09320"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97292.1"
                     /translation="MALRSRWSLAAALCAAACLLGPIKPHAGEPPQALCADWKSHHPE
                     WIWCDDFEIDRLSHYFEYDIRHGRFVREAGAGVGASTGMRAEFLPGDPHGGSLHLAFG
                     KTPSEYMKPVDAGTANYRDIYWRFDLRLQPGWTGGGADKLTRATILSSNRFAQAAIGH
                     LWSGAHPGSDPDRLYLDPASGTDEFGTLLTTTYNDFPRLRWLGAAGGQTALFNPAHIG
                     TWFCIEMHMKLNSRDAADGVLEYWIDGQLEAQRTNLNWIGMYNEYGINAVYLEQYWTS
                     VPFSKVQQRYFDNFVVSTARIGCAR"
     gene            2302..4446
                     /gene="ppk1"
                     /locus_tag="PK063_09325"
     CDS             2302..4446
                     /gene="ppk1"
                     /locus_tag="PK063_09325"
                     /EC_number="2.7.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009358 - polyphosphate kinase complex
                     [Evidence IEA];
                     GO_function: GO:0008976 - polyphosphate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006799 - polyphosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate kinase 1"
                     /protein_id="HMZ97293.1"
                     /translation="MALRSTASHIEPQSATPAPKVSSVRPVTSDLSRPEWFINRELSL
                     LEFNRRVLDLAKDPKVPLLERLKYLCIVSSNLDEFFEVRVAGLKEQVTHGVEQRGADG
                     LTPSELLARIAVLTHQLVQEQYVVLNQSLIPKLADERIRFLKRADWMPSHIRWMRRFF
                     SRELLPLLSPVGLDPAHPFPKLLNKSLNFLVTLEGTDAFGRPNGTAIVQVPRSLPRVI
                     HLPVRNAAWPHDFAFLSSVIHAFVHQLFPGMHVTGCYQFRVTRNSNLFVDEEDVDDLR
                     RALEGQLPDRRFGDEVRLEVADNCPPDLVYFLREQFHLDARDVYQCHGPVNLHRLMAV
                     PDLVDRPDLKFQPFTPGVPTTPVPSEDWFDAIRQSDILLHHPYQSFAPVTEFLRQAAT
                     DPHVLTIKQTLYRTGADSAIVQSLVDAARGGKEVTVVIELRARFDEEANIELAHDLEE
                     AGAHVVYGVVGLKTHAKMSLVLRREGRLLRSYTHLGTGNYHARNARLYTDFGLLTCDA
                     AIGRDVRTVFQQLTSLGQPGRLKHLLQSPFTLHTTLLKWIARETDRARQGKPAHIIAK
                     MNALLEPQIIRALYKASQAGVKIDLIVRGPCALRPGIAGLSEHIRVRSIIGRFLEHSR
                     IFYFLNDGDDRVFLSSADWMDRNFFRRIEVAFPVLDPILRHRLIEEGLRPYLEDNTHA
                     WILHRDGTYKRQTPGRRAARSAQQWLMNRLVT"
     gene            4581..4973
                     /locus_tag="PK063_09330"
     CDS             4581..4973
                     /locus_tag="PK063_09330"
                     /inference="COORDINATES: protein motif:HMM:NF013427.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HMZ97294.1"
                     /translation="MAVAHVVRPRSRHQAFRSIRRQLLQDQRILLRQAASWRPPETEA
                     ELPADVLDIATCDRDLALGDLMRQRTYAKLQQITRALNRLDHASYGMCHLCRTDIPLP
                     RLRAQPDATLCVDCKAECEHRAMLRKQV"
     gene            complement(5680..6432)
                     /locus_tag="PK063_09335"
     CDS             complement(5680..6432)
                     /locus_tag="PK063_09335"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97295.1"
                     /translation="MNRMVIAIVAVACLVNAACVSKPPKKQFQRLAGEFVSPVHITKP
                     VDQQSAVIGITIKSSAWVPNTEDRLYLVKIENDRDLFEGAKLIPTSIVSPPPGAGGGG
                     TVYVQNVPPGRYAAVAFSTSEKGFGKVREVTLFLLPKSVVKQSDTTVTAGSMHFMGEY
                     EVGASTMVLQENAADEVQAHYFEAFWGKPLAQVIADLQVLGTPAYFAVHTVNVKGGSR
                     DADAEARFQATAKRDLEPSWAPVIERARVPKK"
     gene            complement(6639..7901)
                     /locus_tag="PK063_09340"
     CDS             complement(6639..7901)
                     /locus_tag="PK063_09340"
                     /inference="COORDINATES: protein motif:HMM:NF037660.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ97296.1"
                     /translation="MNMRSNALAFTIGLAILGTLSGCAEDHRWRAAMNDGNTAMRSGD
                     YTHAEESFVAARKEAEVLDPQGKRLAETLSQLGEVNRELGRYPRAEALFQEALAIRER
                     VYGPAHAETAASLTDLGELYRLQGLYTQSEALHQRAREIREKVFGPDHSKTAESLNNI
                     AVVYQDQRRFADAEPVLQRALAIFEKQLGPEHSLTAITRDNLAKMYQAQGQHPRAMPL
                     YQRALTIHEKAFGPNHPIVARNLENLGDTYRAQNQYPQAEALYQRAVSIFRKSIGSDH
                     VDTAEAMSRLGQLYELQGLYSQAEPLFQQAIAIREKQQGADNPQVAGELKNLASLYQS
                     QNKLDQSEDLYKQALVIYEQAVGYDREAYVKTLKSYASLLRRRQRSGEAERLEERAKS
                     VLKRLSLESQSQGKTAADLPLAPVSPVP"
     gene            complement(8130..10148)
                     /locus_tag="PK063_09345"
     CDS             complement(8130..10148)
                     /locus_tag="PK063_09345"
                     /inference="COORDINATES: protein motif:HMM:NF013530.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HMZ97297.1"
                     /translation="MTNPSPNTPVSGPLRIALIGAGRHAQHHARAILRCPGVQLVAVA
                     DPSDAAQAAMRDIVPGIGCFKTPEELFASEKLHVVHIITPPATHAPIARMALKAGCHI
                     YVEKPFTESVEDAQQILDEASAKGLRVCAGHQLLYEPPTRVLTQYLRSIGRVVHVESY
                     FSFRTVRHAPGGRKVLRADHQLLDILPHPVYLLLQVLEQAGEGRTELLSLEVSQAGTV
                     HALVRRGGVTGTLIVTLEGRPVESYLRVIGKNGSLFADYVRSTTQRAIGPGSSGIDKL
                     FAPYRQAWQLLTGTTSAMASRFLKSQRSYPGLAELFSAFYESARTGNPSPLSPESLLE
                     TVRICERVAKALKVGEAKALAAAAPKPVESRGVLVTGGTGFLGKEIVRALLSRGRPVR
                     VVARREPSPWERIAGAEYVVADVATGAAAHLFKGVDTVIHAAAETAGGWPEHQRNSLD
                     ATEHMLRGAAAVGIKHFVHVSSLAVLAQGTGRPIPDDHPLEPDSKGSGPYVWGKLESE
                     RLAVQLGKDLGVSVKVIRPGALVDYRDFDPPGRLGKRLGNIFVAVGSPGDRLGVVDVG
                     FAGRFLGWMTDAWDMAPSPLNLLDPVSPTKRELLDRLRQANPDLSVFWLPRFVLIPLS
                     WVATLAQKVLRPGKPAIDVAKVFSVLPYDTSGIATLAPRVDSASELHR"
     gene            complement(10308..11303)
                     /locus_tag="PK063_09350"
     CDS             complement(10308..11303)
                     /locus_tag="PK063_09350"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ97298.1"
                     /translation="MDAASILIVEDEPVVAKDIQLSLQRLGYRVPATATSGEEAIRKA
                     GDTHPDLILMDIVLKGKMDGVETALQIQRRQDVPVIYLTAYADNHTLERAKVTSPAGY
                     MLKPYQANELRTTIELALHRAQHDRHMRARLRWIATTVRCIGDGIVTTDRGGRVTYMN
                     PAAEEFTKVTQDEAMGMSVTALMGFPDDGATQHGGNPANQAMAEMRLVTIDEATVMSR
                     QGEPRSIRGSVAPVVDDGGAVLGAVFVFHERVPGERHLGPSNVQAEAIWRMEERLGRP
                     QGIINLCSWCKRVPDQSGEWYDLATFIAERSAIQFNGGLCPECMDQCFPCNGKHK"
     gene            complement(11308..13140)
                     /locus_tag="PK063_09355"
     CDS             complement(11308..13140)
                     /locus_tag="PK063_09355"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ97299.1"
                     /translation="MTIPSSYFLGMSRSSYSILGVALALIAVIGAIDWWLPLGLTITT
                     LYVVPVLIASRIPYPRLTFWVAATASFVTILDLFHSPLYALTWVSAVNRAFALMVIWV
                     TALLCLRRQRDEAELLRINEDIEQQVQERTSDLAAANQELEVLRAEAVSELVAIVKSS
                     DDAIVGMTLTGIIQSWNRGAERVYGYSAEEVLGRPISVLCPPNRLDEVPTMLDRIARG
                     EHVRNVEMVQRRKQGERIDVSLTISPVKDSDGCVMGASAIARDVTVKKRIEAALRESE
                     ARFRMMADTAPVMVWMAGPDTHITFINKRWLEFTGRTMQEEIGDNWFTGIHVDDLERC
                     RKSYLDAFKSEQPFFLEYRLRRHDGEYRWIMDTGVPLFDEDGRFGGYIGTCMDLTERK
                     DMEDQLRRMLKEKESLLREVHHRVKNNLQVISSLLNLQSASIKDPVVNQLFRECQVRI
                     TSIALLHETLHRSNDLSRIKMGDYTRTLTGHLFRSYGVDPGLISLELNVDDVEFDIDT
                     GLTCGLIIDELVSNCLKHAFVESGRGTVHIDLLDHVDGTFTLCVSDDGIGIPTDGVLN
                     NPDSLGLELVTLLAEKLDGHTELRSGSGTEWRIRFQQLQYSERV"
     gene            complement(13658..14776)
                     /locus_tag="PK063_09360"
     CDS             complement(13658..14776)
                     /locus_tag="PK063_09360"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HMZ97300.1"
                     /translation="MNIPLLDLKAQYQSMRSEILAAIEATCDEQGFILGPRVVALEQA
                     VATYVSSTHAVGVASGSDALLLALMALGVKAGDEVVTVPFTFFATAGAISRLGAKPVF
                     MDIRPDDFNMDPTLLERVITKRTKAIIPVHLFGQCADMGAIHDIARRHKIGVIEDACQ
                     AIGAAQNGKRAGVLGDLACFSFFPSKNLGGFGDAGMVTTNDKELAESIAMLRVHGSRV
                     RYVHEAIGINSRLDALQAAVLLVKLQRLDQWADGRRRNAARYHQLFTDAQLTDHVTLP
                     VTHPHNFHVFNQFTLRVRKRDELRAYLKDHGVGTEVYYPLPLHLQNCYRDLGYQKGAF
                     PQSERAAEEVLSIPIYAELTDEQLQYVVQMIAAFFRKR"
     gene            complement(14797..15987)
                     /locus_tag="PK063_09365"
     CDS             complement(14797..15987)
                     /locus_tag="PK063_09365"
                     /inference="COORDINATES: protein motif:HMM:NF012744.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HMZ97301.1"
                     /translation="MDVICHVITKLELGGAQEVAMRVVSGLDRRRFRPVLIAGPGGLL
                     TEEAHALEGVDVRLIPSLVREVHPLQDLQALFELVATFRRLRPKIVHTHSSKAGILGR
                     LAAWLAGVPCILHTIHGYGVTPAQPLWLQHLVIKLEWMVGRVTTHWIAVSQADRRQGL
                     EWELFSASKVSVVRPGIDPTPFAARIEQAERDRLRAALGVGPEQLLVGTVSCLKPQKS
                     PEDFIRVAALVCQRMPAAKCVLAGDGALRPQIEAMIQAQGLQDRVSLLGWRRDVASLL
                     KAFDVFVLTSQWEGLPCAILEARASRIPIVATRVGGSAEAIIEGIQGTLCPAGDVKAM
                     ASRVCQILGDERLRADLRNGAQELPEEFTIQETIKQYHSLYTYLLHATRPAEDVMKLQ
                     PNRL"
     gene            complement(16001..17311)
                     /locus_tag="PK063_09370"
     CDS             complement(16001..17311)
                     /locus_tag="PK063_09370"
                     /inference="COORDINATES: protein motif:HMM:NF013739.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HMZ97302.1"
                     /translation="MIVIVGAGLAGLSAAYHLRGMPYKILEREREVGGLCRSYVKDGF
                     TFDYTGHLLHFRQTAIKALVESLLPDRLQRHARKSFVFSHDTYTEYPFQVNTYGLPPE
                     VVRECLLGFIATLSRSPSTPPAENPSFKQWIIESLGEGIAKHFMVPFNEKLWQVPLDE
                     LTSDWVSWLVPKPDVKDVVSGALGIKDKAFGYNPSFQYPVSGGIKVLPEAFLPSVENL
                     TYGSELVEIETGRRRAVFRSAQGERIEEYDRIISTIPLPELVRRCVDLPASMRELAGA
                     LRWVSVYNVNLAVAREHVSDKHWIYFPEHRYPFYRAGFPMNFSPSMGQPGCSSLYVEI
                     SHQPTEKESETSLIERVRRGLEGAGVLQPTDELVMSDVKDLYYAYVLFDRYRSRAVKE
                     LLAELERRGISSIGRYGLWEHTSMEDAIAQGQQLAMRLRMRAAA"
     gene            complement(17308..18366)
                     /locus_tag="PK063_09375"
     CDS             complement(17308..18366)
                     /locus_tag="PK063_09375"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: protein motif:HMM:NF013146.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HMZ97303.1"
                     /translation="MILLALTFLVAVLLSVYGVPIARRAALKFGIVDSPDGRLKHQGE
                     PVPYLGGLAIYLSFLVSLAFTFEFRQDVLGIVLSGTLIVMLGLIDDFGVLSPGTKLAG
                     QFLAVFVLIKSGIRIEIASLPDWVDILLTVFWMIGIINAFNLLDIMDGLSAGVGVISA
                     AFLCVVAILNGDQTIAFMLAALMGSLLGFLRYNWRPASIYMGDSGAMFIGLMLGALSM
                     IGKYTQGHSVSLLTPVLILGMPIFDTLFVMYIRFLRGLPVFLGSPDHIAIRLRHWGLS
                     VTHVVLLSYLGAAILGGIGLLVMAVPQDLALILSGVTVLCLAAAAVALTRVNVSSGVV
                     AVSPEAVPARSTERTGAV"
     gene            complement(18363..19502)
                     /locus_tag="PK063_09380"
     CDS             complement(18363..19502)
                     /locus_tag="PK063_09380"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF025072.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HMZ97304.1"
                     /translation="MTVTYFSKSSSIGPSSRYRVYQYLPHLYNAGIECHVEPLFGPTY
                     FSILHIRSLMLQTVLKIPYVVARFLKRLGTLMMLGQRDLIVIEGQLFPYAPPLVERLL
                     CWLGYRLVIEMDDAIYLTRGHERKMPVLFRMATGVIVGNDRLAAYATQYSSKVTVVPT
                     VVDTERFAPRPLRPTAASHLLDDPITIVWIGLAYNLKYLNVLAPAIRRLQERYRVKLR
                     VVCSQPPVLDGLDVEFRSWEWRREVEDLQDATIGVMPLEDTEWARGKCALKLLQYLAV
                     GLPAVASPVGVNRDILVNGDNGFLASTEEEWYLRLESLCRDPQLRARMGQAGRRTVET
                     RFSLAVWGPKLADVYRAFAEDAPSRQMPRPVGLSVRGHGHSTGMR"
     gene            complement(19674..21500)
                     /gene="asnB"
                     /locus_tag="PK063_09385"
     CDS             complement(19674..21500)
                     /gene="asnB"
                     /locus_tag="PK063_09385"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: protein motif:HMM:TIGR01536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HMZ97305.1"
                     /translation="MCGIVGVCDRMEPQQAHHVLSRMLATMIARGPDGEGRFVDPHIA
                     MGMRRLAVIDVEGGGQPLFSRDGQVVAFQNGEIYNHAALRRELAQRGVECRTASDTEV
                     LAHGYDHWGMDGLLARLDGMYAIAILDQRNHQLHLARDRFGEKPLYYSVANGKFAYSS
                     NTTALAWLPWGDRDIDAGSVDRYLALHYVPGRRTMFKGIQRVLPGEHISISLDSLQII
                     HDRYYRPAMGPIEPVDTGTLVGRIEAAVTSRLVADVPVGVFLSGGIDSSIVAALAAKH
                     HPAIDTFSMGFKDARYDESPHAQAVARAIGSSHHHFTFDETAFHDLLPSVIDGLDEPL
                     GDQALLPTYWLCREAKRHVTVVLSGEGADELFAGYEYYGALLSRRSWRACLKAWVMGR
                     GPADELQRLCDNVWPVTPSGFPLVMDTAGRRQLLGGYAPDRDPWEEALRSTLQQSANG
                     LQRATLADVLTWLPDDLLVKLDRMAMANSLEGRAPFLSPVVAETALRLPESSRMTPVR
                     SKVALREVAARLLPPEIVHRRKQGFVLPMATWLKQWLRRVENLYEYFDLQRIAVFDGN
                     AAATLVERQLTSDRPNERLLFSLVMLAEWHHSFFRRIPPAKF"
     gene            complement(21517..22560)
                     /locus_tag="PK063_09390"
     CDS             complement(21517..22560)
                     /locus_tag="PK063_09390"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF013382.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HMZ97306.1"
                     /translation="MEQRLRSMLLPGMRRLGLVPLLRRLRAGFRSAGNAEPAGSGHPG
                     NDHDRVSDYWGQQFQAMRVDNSYWLNNKLVEEATYRLMTDTPRHWLGWLLNDYFAQRT
                     FDRSLSVCCGDGAHEIQLYTSGKVRFVSGVDISEGAIKQAAARFAEAGAPADCYRFEV
                     RDVNALQLEDQYDLIFSTGALHHTTNLEALLSTVERALTPNGYFVVVEFIGPNRFQWT
                     DRQIEIANQVLNVLDPAYLRDGRNTRFERPTIENMLACDPSEAVRSADVYPLVKKYFD
                     VRYERFYNGTLLHQLYPLLRTELANQGKRDFDSIVKLILLLEDLLIKGNVLPSDFVFL
                     ICQKPVPGSRRAA"
     gene            complement(22686..23825)
                     /locus_tag="PK063_09395"
     CDS             complement(22686..23825)
                     /locus_tag="PK063_09395"
                     /inference="COORDINATES: protein motif:HMM:NF019846.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HMZ97307.1"
                     /translation="MTVRFNLETPGGPQLNTINRFSGWYIPDHGRRPELYVACNGKRA
                     ASLEWGSVRPDVSSVYSTHSQAIISGFQGDLLMGEQEQAQAVEVVVLDAAGQDRELFR
                     RTYAVGPYRPPVIRDRSFNLFELLVCPECRSPLAKQDQGWMCPRCARLVPLKGGVPHF
                     LQEQGTPCLHVTEQTNTHPYSADVLDILGRHRAGLVLDFGAGHTPKELLRPHVVYLDA
                     VQYEWTDLVCTRARLPFRDHSFDAVVSQAVFEHLEDPHYTARELCRILRPGGIIHLDT
                     AFMQPLHGDPWHFFNMTQHGLRKVMAPFEEIRCGIKSYQHPSASLLMQFDAIAPFITS
                     RKWRNTIAKWRKELEAGAGEFDDALGEAGRTTLAAGFFFEGRRPQ"
     gene            complement(23822..26884)
                     /locus_tag="PK063_09400"
     CDS             complement(23822..26884)
                     /locus_tag="PK063_09400"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF025025.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HMZ97308.1"
                     /translation="MNRLMQRLIKAIRFSRFAIVEGLRWYKRHGRLPRKAECADLFRK
                     AFFRFKILAQRISPAPKTIEPVLPPYDAWLKVNVWNRRMRDDLLDRLSRHAGRLPTIS
                     LVMPVHNPPLECLTKAIDSVRAQVCGEWELCIADDCSTNPAIRDELERFRAEDPRIRL
                     TYLERNLNISLATNRAADLATGEFLLFFDHDDELTPDAVGEAALYLAEHPEIDALYSD
                     DDKIDSAGKRYAPQFKPDWSPELLLSYMYMSHIFVVRRSLFETVGAMRQGFEGAQDYD
                     LALRVAERTGMVGHIPKVLYHWRALPGSTASSGAAKPASIEAGRRAVAEAFERRGIAV
                     RVTQPEFAAAGNLGIYCHEFPDDGPTVTILIPTKNQVTVLRQCVESLRATTYRQYEIV
                     IIDNESDDPETLAYLHSLPHRVIRLGNPSGRFNFAAINNRAVEQVTGEFILFLNNDTE
                     VKSPRWLSQMVGYAQMPGVGAVGAKLIFADGRIQHAGVIHGLYHGMAGPAFKLTPSWE
                     HGYLAYASVVRNYSAVTAACLLTSRRRFLDVGGFNEAEFGVAYNDVDYCYRLVDQGYR
                     CVYCPDAQLMHYEGYSRGFRDDPAEVAAFKQKYKRRQDPWYSPHLSLVDESFNLVPRA
                     VAARRQKPIPMVMTALSLNCEGAPWSQYELTKELVRRKVIQPIVFSPLDGPLRSLYEE
                     EGIPVMVDRHPLWGVTTLKEYEEAVKVFSSKCLSWGAELIYANTLQSFYAVAAAQIAG
                     IPSVWNPRESEPWQTYFDYLPDGVIQKAYDCFASPYRVVFVADATRDAYAALNTRHNF
                     TVVRNGLDQTRIQQTSEEWLPAQARQSIGACDGEVVILLLGTVCPRKGQQDLVKALAQ
                     LSPDLQKRVRCYIVGDRPSEYSAGLHALVAQLPSELRSRMHLVPETRQTARYYRAADL
                     FVCTSQLESYPRVVLEAMAYGLPIVTTPVFGIREQVREGVNALFYEAGDSGALADRLR
                     RLLQDEALRARLASKSASVLALGTDFDEMVSSYAEIFAEAWLSGGPLS"
     gene            complement(26977..27924)
                     /locus_tag="PK063_09405"
     CDS             complement(26977..27924)
                     /locus_tag="PK063_09405"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HMZ97309.1"
                     /translation="MNKTVNESTELEATGERFLPEMQGTIALEHLHRYALAKDCAAGK
                     IVLDIACGEGYGSAVLAGTADRVYGVDIAPDAIAHARAIYQRPNLEYLVGECANIPLP
                     DCAVDLVVSFETIEHHTEHEAMFAEIKRVLRPGGVMVMSSPDKLEYTERSGHANAYHV
                     KELYAEEFQRLVERYFNRVAMLGQRVLYASAILPQGAPGEAVHYSRDKDSAIQAASGL
                     VRPCYQVAIASDAALPPVLSSLFEQAGESDPEIHALQHQLEHAGRRILGLEEEVAGLK
                     AAIELMMNSHSWKATRPLRAVANALRAVSGNRVEKSRRA"
     gene            complement(27921..28655)
                     /locus_tag="PK063_09410"
     CDS             complement(27921..28655)
                     /locus_tag="PK063_09410"
                     /inference="COORDINATES: protein motif:HMM:NF019846.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HMZ97310.1"
                     /translation="MNASMIPLPCKVCGGSTFSHHDVLWGDLIAQWGLSSREVDYINV
                     QQGTACTGCGSNVRSIALADALLRWTRATTTLQEWVHTPVARRCDVLEINEAGSLTGT
                     LSTLPGHRLVRYPEYDMMALPFEDRSFDVVLHSDTLEHVPDLMKGLRECRRVLRPGGA
                     CLFTVPVVVGRLTRGRKGLPLSVHGSEGCIDTALTVHTEFGADVWCQVLESGFDECRI
                     VPYRYPAGIALIAEVAESRPVTGGQW"
     gene            complement(28624..29997)
                     /locus_tag="PK063_09415"
     CDS             complement(28624..29997)
                     /locus_tag="PK063_09415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ97311.1"
                     /translation="MSSEWAIRVRQLSKTYRVYDRPRDRGKQWILPPLQKCFGQSPSR
                     YYREVHAIEDVSFEVQKGETLGIIGRNGSGKSTLLQLIVGTLSPTSGTIETDGRIAAL
                     LELGAGFHPEFTGRENVFLNATLLGLSQADIDARLDDMLAFADIGSSIDQPVKTYSSG
                     MVVRLAFAVMAHVSADILVIDEALAVGDAFFVQKCIRFLRAFMERGTVLFVSHDSAAV
                     LSLCRTALWLEHGRIAGKGEAKVICDGYLHQPTPMEIPREKVAEGLPSSDPSDPAQPI
                     QNDSSNLAVLPHHETRSASHSRPAWIETITLCNANGRTVHTVTQREQVTLRVCCVTSV
                     GLASPIVGFLVRNRFGQSLFGANTCAAGNAAGHGVSPGTRFVAELEFVMPVLHPGDYA
                     MSIALADGTQEEHVQQHWIHDALAFTSAPSEWCFGLIAVEVMRTQICEIEAQDAQHER
                     LHDSIAL"
     gene            complement(29987..30811)
                     /locus_tag="PK063_09420"
     CDS             complement(29987..30811)
                     /locus_tag="PK063_09420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HMZ97312.1"
                     /translation="MVFQRYGLSPLIVLTSMSAHWNLIRQLTKREIASRYRGSLLGML
                     WAFLHPMVMLTVYTLVFRGAFGMRWGQDGESALDFGLLLFSGLIVHALFAESIHRAPY
                     LIVNHSNYVKKIVFPLEILAWTSLGSALFHALISALVLIAFYGFLHHDLHWTMLLVPL
                     LLLPLSLVTIGISWFLASAGVFVRDIGQASGPLTTVMLFLSPVFYPAGAFPEAYRILL
                     YANPLTFLITQAQDVLIWGRPPSWIGIGLYCAGSYLIAWCGLLWFQKTRKAFADVL"
     gene            complement(30928..31692)
                     /locus_tag="PK063_09425"
     CDS             complement(30928..31692)
                     /locus_tag="PK063_09425"
                     /inference="COORDINATES: protein motif:HMM:NF024091.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HMZ97313.1"
                     /translation="MGAIGVIAVNAFRESLRDKILYNLVLFAGLLIGLSVLLADLSIT
                     EHHKVIADMGLAAINLIGVIIAIFVGISLVNKEIERRTIYTIMARPISRTFFIMGKYL
                     GLALTLFVNLAIMLAVFLLTLWLYHVPIQTSLFQAVALIFVEILVVTAIALFFSTFTS
                     TTLSAIFTLGLYVIGHLTADLRSMVANSESGAVKGVVDLLYYLCPNLEMLNIKGQAAV
                     GLVVAPEYLMLASLYGLLYASLLLTGACLVFQQRDF"
     gene            complement(31694..32665)
                     /locus_tag="PK063_09430"
     CDS             complement(31694..32665)
                     /locus_tag="PK063_09430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ97314.1"
                     /translation="MDDIVTHNLTKTYASGWPGRPPFVALDGLSLTVGRGEIFGFLGP
                     NGAGKTTTLKILMGLVRPTSGTALLLGQPAGDVATRRRIGFLPESPYFYDYLTAEEFL
                     GFYGRLAGLNRSAITQRVTDLLELVGLVEARTRQLRKFSKGMLQRIGLAQALIHDPEL
                     IILDEPMTGLDPVGRKQVRDLILSLRDCGKTVFFSTHILHDVEMICDRVGIVMKGRLV
                     ASGRVDELVRQDHTRSVEVVCQQLKVEGNAFIHSLATRVLQQGQQCLIVLPSPDAVDA
                     LVGEIRRQGGQLLSITPHKASLEDLFFQEAAQATTRVLPHMTSGRAS"
     gene            complement(32678..33634)
                     /locus_tag="PK063_09435"
     CDS             complement(32678..33634)
                     /locus_tag="PK063_09435"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97315.1"
                     /translation="MRGRTDIRSRLSHVLCVLVLLIGTSGVLHILEGERTAVARAEQL
                     AYLPKGEYFKLAVLGYRQVVADLIWLQAVQHIGAKRDTQLGHTWTYHAVDVLTDLDPT
                     FVPPYQATGLFLGVLVGRHDEGVAILRKGIRHNPANWQLPFLAGYISYYERCDASAAG
                     EFFQLAAHVPGSPAYLPQLAARMTVESGDPTAALEFLDRFSRSVADDRVREALFRRMK
                     EIVQEQDLRFLEESIRRYRLKYGQAPAKVEDLMLHGIIPRLPEDPLGGQYEIDGLTGI
                     VSASSKRDRLRIHEKVACRLGVASTPSTQADAIETLQPAVQQ"
     gene            complement(33640..>33927)
                     /locus_tag="PK063_09440"
     CDS             complement(33640..>33927)
                     /locus_tag="PK063_09440"
                     /inference="COORDINATES: protein motif:HMM:NF025910.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ97316.1"
                     /translation="YEQARLHWMLGERPLAEQQAKEAEQLEPNFLPARALLARLSVDA
                     GRIDDARRELQEIQVRQARYEQWNKNNIDRTFLSVDVAPLRAAVEAKGLAG"
     assembly_gap    33928..34027
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<34028..35279)
                     /locus_tag="PK063_09445"
     CDS             complement(<34028..35279)
                     /locus_tag="PK063_09445"
                     /inference="COORDINATES: protein motif:HMM:NF016800.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HMZ97317.1"
                     /translation="MIIRLVILAWLGGTLIQAIRAGRLIVPRLGARYVVLAFLGFAVA
                     ATIFSPYVHQSRQWLVMITGYAILFYLLVSVVDRWERVHTLTMMVIVMGLGEAAWTIV
                     QGVVWNVVRPSGTFFNPNFLAGYLTVSWAVLLSIAVYGYRKSAILYRSSVSPVFWWAG
                     MGSALGIVLIAMIFTQSRGGLVAWLAATVWILTARYGWKLAGMGTAALLLAALIVPTP
                     LKERVLAEHEQNPVSYARWQMWQGAIAQMADHPLGIGLGLYQYTYPLYAFPVEGEITR
                     YGKVAHTPHNDYLQIGVEMGVGALLVFLAAIGLVMRDLLQVLQARLVRWQRSLILGIG
                     GGGIALLVHAALDSSLRESALAILLVLCAGLIVSVARITSGNTDALHAIPIQSRPLWG
                     MGAACLLLLVGAEVSRLGMAWLTFD"
BASE COUNT         7948 a        10795 c         9602 g         7008 t
ORIGIN      
        1 aaccattccc ggcaccgtta tggcgctctg ccggttgaat gtgccgtcgc tcatgattta
       61 cggcggatcg atcatgccgg gacagttcca gggacatgat gtcaccatcc aagacgtgtt
      121 tgaagcggtc ggcaaacacg cgtcgggcaa gatgacgaat gccgaactga aagacctgga
      181 agaccatgcc tgcccgggac ccggtgcttg cggcggccag tttaccgcca acaccatggc
      241 catcgccttc gaatttctcg gcatgtcgcc gatgggacgt aacggtgtcc cggccatgga
      301 tgtgcgcaag gacgatgtgg cgttcgagtg cggcaaaatg gtcatggacc tgcttaaaaa
      361 ggacattcgc cccaaacaga tcatcacccg ccgctcgatc gaaaatgcca tcgccgccgt
      421 cgcgacaacc ggcggttcga cgaatgcggt cctgcatctg ctggccgtgg cgcgcgaaat
      481 gggtgtgcgg ctcaccatcg acgacttcga taagatcaat cgcaaggtgc cgttgttggc
      541 cgatctgaag ccgggtgggc acttcaccgc ggcagatctc tatgcggccg gcggcacgac
      601 cctggtggcg aagcgcctga tcgatgcgaa gatcctccac ccggaccaga ttaccgtcag
      661 cggacggacg atcggcgaag aggccaaggc cgctacagaa aaacccgacc agcaggtgtt
      721 gcgcccgctg tccaagccga tcaagccgac tggcggcctg gtcatcctca agggcaacct
      781 ggcacccgaa ggctgcgtcg tcaaagtcgc cggtcattcc atcctgcatt tcagcggacc
      841 ggccaaggtg tacgagcgcg aagaagatgc cttcaaagcc gtgcaggccg ggaagatcaa
      901 ggccggcgat gtcgtcgtca ttcgatacga gggaccatcc ggtggaccag gcatgcggga
      961 aatgctcggc gtgacggctg cgatcgtcgg tgcagggctg ggcgattcag tcgcgctgct
     1021 caccgatgga cggttctccg gcgcgacgca cggactgatg gccggacatg tcgcccctga
     1081 agccatcaag ggcggtccga tcgcagccgt gaagaccggg gatgtcatca cctttgacat
     1141 cgtgaaacgg cgcttggacg ttaacatcac gcaaaaggaa atggcctcgc ggctgaagaa
     1201 agtcaaacac cctgccccgc gctatctttc cggggtcatg ggaaagtacg cccgccacgt
     1261 ctcctccgct tccgaagggg cggtcaccag ctagccatgg cactacggtc tcgatggagt
     1321 ctcgcggcgg cgctctgcgc cgccgcctgc ctcctcgggc cgatcaagcc ccatgcaggc
     1381 gagccacccc aggctctgtg cgcagattgg aagagtcacc atccagaatg gatctggtgc
     1441 gatgatttcg aaatcgaccg cctgagccat tacttcgagt acgatatccg gcatggccgc
     1501 ttcgtccgtg aagccggagc gggagtcggc gcctcgaccg gcatgcgagc agaattcctg
     1561 ccgggtgatc cgcatggagg ttcgctccat ctggccttcg gcaagactcc aagcgagtat
     1621 atgaagccgg tcgacgcggg aaccgccaat tatcgcgaca tctactggcg gttcgaccta
     1681 cggctgcaac cgggctggac cggtggcgga gccgataagc tgacgcgagc gacaatcctt
     1741 tcgagcaatc gatttgcgca ggcagccatc ggccatttgt ggagcggcgc tcatccggga
     1801 tcagaccctg atcgcctcta cctcgatccc gcatcgggca cagatgaatt cggtacgctg
     1861 ctcacgacga cctacaacga tttccctcgc ctacggtggc ttggcgcggc cggcggccag
     1921 acggcgctgt tcaatccagc ccacatcggc acctggttct gcatcgaaat gcacatgaag
     1981 ctgaatagtc gggatgccgc agatggtgtc ctggaatatt ggatcgacgg gcagctggaa
     2041 gcgcaacgga ccaatctgaa ttggatcggc atgtataatg agtacgggat caatgccgtg
     2101 tatctggaac agtattggac gtcggtcccg ttcagcaagg tgcagcagcg ctattttgac
     2161 aattttgtgg tctccacggc tcgaattgga tgtgcccgat aaacgggaca ccggcaaggc
     2221 ccccgcacag tgagcggaaa agttaaccgt ttcttgatct gtcatcacac caggctggtg
     2281 tagactgctc acccattacg tatggcatta cgctccacag catcacacat tgagcctcag
     2341 tcagccacac cggcaccgaa ggtgtcatcc gtccgcccgg tcacgagcga tctctcccgt
     2401 cccgaatggt tcatcaatcg agagctcagc cttctggaat tcaaccgccg cgtgctcgat
     2461 ctggccaagg acccaaaggt ccctctgctg gaacgcctca aatacctctg catcgtcagt
     2521 tccaatctcg atgaattttt cgaggtgcgg gtggccggcc ttaaggaaca ggtcacgcat
     2581 ggagtcgagc agcgtggggc cgacgggctg acgccatcgg agctcctggc tcgcatcgcc
     2641 gtgctcaccc accagttggt gcaggaacag tacgtggtcc tgaaccagtc gctgatcccg
     2701 aaactcgccg acgaacggat ccggtttctg aaacgggccg actggatgcc atcgcacatt
     2761 cgctggatgc gccgcttctt ctcacgcgag ctgcttccat tgctgagtcc ggtcgggctg
     2821 gatcccgcgc atccgtttcc gaaactgctc aataaaagtt tgaactttct ggtgacgctg
     2881 gaagggaccg acgcattcgg acgccccaac ggcacggcca tcgtccaggt tccgaggtcc
     2941 ctcccgcgcg tgattcacct tcctgtgcgc aacgccgcct ggccgcatga ttttgcgttc
     3001 ctgtcctcgg tcatccatgc ctttgtccat caacttttcc ccggcatgca tgtcacgggg
     3061 tgctaccaat tccgcgtcac gcgaaacagc aacctgtttg tcgacgaaga agacgtggac
     3121 gacctccgcc gtgccctcga aggtcaactg ccggaccgtc gcttcggcga tgaggtgcgg
     3181 ctggaagtgg cggacaattg cccgccggat ctggtctatt ttctccgtga gcagtttcat
     3241 ctcgatgcgc gagacgtgta tcaatgccat ggaccggtca atctccatcg actcatggcc
     3301 gtacccgatc tcgtcgatcg ccccgacctg aagtttcagc cgttcacacc cggcgtgccg
     3361 accactccgg tgccgagcga ggattggttc gacgcgatcc ggcagagcga catcctgctg
     3421 catcatccct atcaatcatt cgcgccggtc accgagtttc ttcgtcaagc agccacggat
     3481 ccgcacgtac ttacgatcaa gcagacgcta tatcgaacgg gggctgattc ggccatcgtg
     3541 caatccctcg tggatgccgc gcgcggcgga aaagaagtca ccgtggtaat cgaattgcgt
     3601 gcccgtttcg acgaagaagc caatattgag ctggcacacg atttggaaga agccggagcc
     3661 catgtggtgt acggggtggt gggactcaag acgcatgcga agatgagcct cgtgcttcgc
     3721 cgggaaggcc ggctcctgcg cagctatacc catctcggca ccggcaacta tcacgcccgc
     3781 aatgcgcggc tctatacgga tttcggacta ctgacttgtg atgcggccat cgggcgggat
     3841 gtgcggaccg tctttcaaca actgacctct ctgggacaac cgggacggct caaacacctg
     3901 ctccaatcgc cgttcacctt gcatactacc ttgctcaaat ggatcgcccg tgaaaccgac
     3961 cgtgccaggc aaggcaaacc ggcccatatc atcgccaaga tgaatgcgct gctggagccc
     4021 caaattattc gcgcgttgta caaggcttcg caagccggag tcaaaatcga tttgatcgtc
     4081 cgtggacctt gtgccttacg acccgggatc gccggcctct cagaacatat tcgtgtccgc
     4141 tccatcatcg gacgatttct cgagcacagc cggatttttt acttcctcaa tgacggggac
     4201 gacagagtgt ttctctccag cgcggactgg atggatcgca attttttccg acgaattgaa
     4261 gtcgcgtttc ctgtcctgga tcccatactt cgccaccggc tcatcgagga aggcctccgt
     4321 ccttacctgg aagataatac ccatgcctgg attctgcatc gagacggcac gtacaagcgc
     4381 caaacgcccg gacgaagagc cgcacgttca gcccaacaat ggctgatgaa ccgactcgtc
     4441 acttaaggcc ttcgccaatc ctccaacttt ttatcccccc tgacggttta accccttctt
     4501 aacctgactg tgatctggct gtcgtgtcca cacgatagcc taatgaccgc accagtcact
     4561 ttaccgatgg aggggctccc atggccgtcg cacatgtcgt ccgaccacgt tcacgtcacc
     4621 aggcgttccg atccattcgc cggcaattgc ttcaagacca acgcatcctc ttgcggcaag
     4681 ctgcgagctg gagaccaccg gaaaccgaag ccgaactgcc cgccgatgtt cttgacatcg
     4741 cgacatgcga tcgcgacctg gcgcttggcg atctcatgag acagcggacc tacgctaaac
     4801 tccaacaaat tacgcgggca ctcaatcgtc tcgatcatgc gtcctatgga atgtgccatc
     4861 tgtgccggac tgatattccc ctcccgcgtt tgcgcgcaca gccggacgcc accctttgcg
     4921 tggactgcaa agcggaatgt gaacaccgcg cgatgctgcg caagcaggtc tgaccatccg
     4981 cgagggatgg gagttgagct gcgccacctc accgcacctc tctcccgagc tgtccccctc
     5041 tactgagccg gagcgggaca gcccccctcc ccattcaact gaacgttccg agtaggcgct
     5101 agcctgagat accgcgagcg gatgtgttac ataccgaccc ggcaatgagg atgatcggca
     5161 gcgaggatgg aatcgtcgta cgcgattagc gacgtcgaga ttggcgttga caacaggacc
     5221 ttataaggcg tcagcagaca ggcgttcgag tcgctcactt atgcactccg ggcagagtgt
     5281 cgcctgaaac ctgcggacgt caaccgtaga gcgaaagtcg ttgtgacatt cccggcagac
     5341 gcggttgctc tggggtacgc catggcgaaa cgtcaacaca tcctgccggc gcgaacgagg
     5401 tcgatagatt tgcaggcctc cctgtacaag ttgcatgtga tcctcctgca ttggtggtga
     5461 gatgcggcga caatgactag cgtacaggag gaagatcacc gcgacttccg gagtaggtaa
     5521 acattgtgtt aacggaagag gcgatgatgg cgaagagagg cgggaagata cggtgcggat
     5581 ctggagcttt agcgggggga ccgatcggat acattacaaa aaaagagccg cgcaccgtcc
     5641 tgacgatgcg cggccgtatc tcgcgtcgct ccgctgttgt tacttcttcg gcactcgagc
     5701 ccgttcgatg accggtgccc acgaaggttc aagatcgcgc ttcgccgttg cctgaaaacg
     5761 ggcttcggca tcggcatcac ggcttccacc tttcacattg accgtatgca ccgcgaaata
     5821 ggcgggggtg ccaagaacct gaagatcggc aatcacttgc gccaatggct ttccccagaa
     5881 tgcttcgaag taatgggcct gcacctcgtc ggctgcattt tcctgaagaa ccatcgtcga
     5941 cgcgccgacc tcgtactcac ccatgaaatg catgcttccc gccgtcaccg tggtatcact
     6001 ttgcttcacg accgacttcg gcaacagaaa gagggtcact tcccgcacct taccgaatcc
     6061 cttttccgat gtactgaagg ccaccgcagc ataccggccc ggcggcacat tctgcacata
     6121 caccgttcca cctccaccgg ctccgggagg aggagatacg atactggtcg gaatgagttt
     6181 agccccttcg aataaatccc ggtcattttc gatcttcacc agatacaggc gatcctctgt
     6241 attcggcacc catgcggaac tcttgatcgt gatgccgatt acggcactct gctgatcgac
     6301 cggcttggtg atatggacgg gcgaaacgaa ctctccggcg agccgctgaa actgtttttt
     6361 cgggggctta ctcacacagg ctgcattgac cagacacgcc acggctacta tcgcgatgac
     6421 cattcgattc atagaacgtc ctctgggtgg gtcgcactta ccggttcggc ggccacagtg
     6481 taggagattc tacgatgcgt ctcaatcgat acttccgaag gggtgcgcgc gggcccggcc
     6541 ggtccaagca gaatggaggg ggtcggacca acgcgttgag aggagaagca ggagcaccga
     6601 tggaggagtc ctgagtccag gaagctgggg gtacactcct aagggaccgg agacacaggc
     6661 gcaagaggca ggtccgccgc tgttttgccc tggctctggc tttccaacga aagacgtttc
     6721 aatacgctct tagcccgctc ctcaaggcgt tcagcttcgc cggagcgttg gcggcgtctc
     6781 aataatgagg catagctctt caacgttttc acataggctt cacgatcata cccgacggcc
     6841 tgctcgtaga tgaccaacgc ctgtttgtac aggtcctccg attgatccag cttgttctgt
     6901 gactggtaga gcgacgccag atttttcagt tcacccgcga cctgaggatt gtcggcaccc
     6961 tgctgttttt cccggatcgc aatcgcctgc tgaaacaacg gctctgcctg cgaatacagt
     7021 ccctgcagtt catacagttg tcccaagcgg ctcatggcct cagccgtgtc cacgtggtcg
     7081 ctcccgatcg acttccgaaa gatgctcacg gcacgctgat agagcgcttc ggcctgagga
     7141 tattgattct gcgcccgata ggtgtcaccc agattttcca ggtttctcgc cacgatcgga
     7201 tgattgggac caaaggcctt ctcatgaatc gtgagggcgc gctgatacag cggcatagcg
     7261 cgaggatgct gcccctgtgc ctgatacatt ttcgccagat tgtcccgggt gatggccgtc
     7321 aagctgtgct ccgggccgag ctgtttctca aagatggcaa gggcccgctg cagcactggt
     7381 tccgcatcgg cgaagcgtcg ttgatcctga tacaccacgg cgatgttatt caggctttct
     7441 gccgttttgc tgtgatcggg gccgaacacc ttttcacgaa tttctctagc gcgttgatgg
     7501 agcgcttccg actgtgtgta caatccctgg agccggtaga gctcacccag gtccgtcaaa
     7561 cttgcagccg tctccgcatg agcaggtcca tagacgcgct ctctgattgc caaggcttcc
     7621 tggaacagcg cttcggcgcg gggataccgg cctagttcac gattcacttc gcccagctgg
     7681 ctcagcgttt cggcgagacg ctttccttgg ggatcgagaa cttccgcctc tttacgcgca
     7741 gccacaaagg attcttcggc gtgcgtatag tcgcctgacc gcatcgcggt attgccatca
     7801 ttcatcgcag cacgccagcg atggtcttcc gcgcaaccgg agagggtgcc gagaatggcc
     7861 agaccaatgg taaatgccag cgcgttcgat cgcatgttca tagtgttaac tcttcgatgg
     7921 tgaggcggtt gtgtttggag actaccttgc ctgcggaata cccttagact tacccgctcc
     7981 gggggctcaa atcaaccccg aggaagcaac tttttcttga agcgacggtt cattcaattt
     8041 ttcagagact tagccattct gaagatcggc gcatacactg tggaatagag gccacgaata
     8101 ccgagcgaag cacaccgtga gggtaaagtt cagcgatgga gttccgaagc agaatcgacg
     8161 cgaggagcaa gcgtagcgat gccggaggta tcgtagggca acacgctgaa gactttggcc
     8221 acatcgatcg ccggcttccc ggggcgcaac actttttgcg ccagtgtcgc cacccatgaa
     8281 agcggtatca ggacaaacct gggcaaccaa aagacgctca agtccggatt ggcctggcga
     8341 agacgatcca gcagctcccg tttggtcgga gacacagggt cgagcaaatt cagtggactg
     8401 ggcgccatgt cccaggcatc ggtcatccag ccgaggaatc gaccggcaaa tccgacatcc
     8461 accacaccaa gccgatcgcc gggcgagccg accgccacaa agatattgcc cagacgcttg
     8521 ccgagacggc cgggaggatc gaaatcacga taatccacca gagctcccgg gcgaatgacc
     8581 ttcaccgaca ccccgaggtc cttcccgagt tgcaccgcca gacgttccga ctccaacttt
     8641 ccccagacat agggccccga ccccttgctg tccggttcca agggatgatc gtccggaatc
     8701 ggccgtcccg tgccttgggc cagcaccgcg aggctactga cgtgaacaaa gtgcttgata
     8761 ccgacggcag ccgcgccacg cagcatatgc tcggtcgcat ccaaggaatt acgctgatgc
     8821 tccggccacc cgccggcggt ttctgcagcg gcatgaatga ccgtatccac tcccttgaag
     8881 agatgagcgg cggctccggt tgccacatct gctacgacat attcggcgcc cgcgatccgc
     8941 tcccagggag atggctcccg ccgcgccact acacgaacgg ggcgtccgcg ggataacagc
     9001 gcacggacga tctcctttcc caagaagccc gttccaccgg tcaccagcac gccgcgactc
     9061 tcgaccggtt tcggggcggc tgccgccagg gctttggcct cgccgacctt caatgctttc
     9121 gccacccgtt cgcagatacg cacagtctcc agcaaactct cgggcgacaa cggcgacgga
     9181 ttgccggtgc gagctgattc gtaaaacgct gaaaacagct cggccaatcc cggataactc
     9241 cgctggctct tgagaaaccg gctcgccatc gcagaagtgg tgccggtcaa taattgccac
     9301 gcctgccgat agggtgcgaa gagcttatca atgccggacg atcccgggcc gatggcgcgc
     9361 tgggtggtac tgcggacgta atcggcaaat agagatccgt tcttcccgat cacgcgcaga
     9421 taactctcga ccgggcgtcc ctccagcgtc acgatcaatg taccggtgac accgccccgg
     9481 cgcaccagcg cgtgcacggt cccggcctga ctgacttcca gcgacaacag ttccgtgcgc
     9541 ccttctccgg cttgctccag cacttgtagg agcaaataga ccggatgcgg caggatatcg
     9601 agtaattgat gatcggcgcg aagcaccttt cgcccgcccg gggcatgccg aacggtccgg
     9661 aaggagaaat aactttcgac gtgaacaacc cgaccgatcg agcgcaagta ttgcgtcagc
     9721 acgcgagtcg gcggttcgta aagcagttgg tggccggcac agacgcgaag accctttgcg
     9781 ctggcctcat ccaggatctg ctgggcgtcc tcgacggact cggtaaacgg tttctccaca
     9841 taaatgtggc atccggcctt gagtgccata cgcgcgatcg gggcatgggt cgccggcggg
     9901 gtgatgatat ggacgacgtg cagtttttcc gaagcaaaga gctcttcagg cgtcttaaag
     9961 cagccgatac ccggcacgat gtcgcgcatg gccgcttgag ccgcatcgga ggggtcagcc
    10021 acggccacca actgcacacc gggacatcgt aagatggcgc gggcatggtg ttgtgcgtgg
    10081 cggccggcgc cgatgagcgc gatccgcaac gggcctgata ctggagtgtt ggggcttggg
    10141 ttcgtcacaa gtagtctgcg aatgtgcagt gctactatag tctattcggg cgcgttcttg
    10201 aagtcttctt cgaaattagt gcaaggagca ggacaggcgc gaaggctcgc cgtcgaccca
    10261 cggaatagcg ctgagtgaca gtacagggat tccaggagcg agtttggcta cttatgtttt
    10321 ccgttacagg gaaagcactg gtccatacac tccggacaga gcccgccatt gaactgaatc
    10381 gcagaacgct ccgcaatgaa tgtggccaag tcgtaccact cgccggactg atccggcacc
    10441 cgtttgcacc acgaacacaa attaatgatc ccctgcggcc gtccaagccg ctcctccatt
    10501 ctccagatgg cttcagcctg tacgttcgat gggccaaggt gccgctcacc cggaacgcgc
    10561 tcatgaaaga cgaacaccgc cccgagcacc gcgccgccgt catcgacgac cggggcgaca
    10621 ctcccgcgaa tggaccgcgg ctcgccttgc cgggacatca ccgtcgcctc atcgatggtc
    10681 acgaggcgca tctccgccat tgcctgattg gcaggattgc caccgtgttg agtcgcccca
    10741 tcatcgggaa accccatgag cgccgtcaca ctcatgccca tggcttcatc ctgggtcacc
    10801 ttggtaaatt cttccgcagc gggattcata taagttaccc ggccgccgcg atccgtcgtg
    10861 acgatcccgt ctccgataca gcgcaccgtc gtcgcgatcc atcgcagccg tgcgcgcatg
    10921 tgccggtcat gctgcgctcg gtgcagagcc aactcaatcg tcgttcgcag ttcatttgcc
    10981 tgatagggtt tgagcatgta gccggccggg gacgtcacct ttgctcgttc cagagtatgg
    11041 ttgtcggcat aggccgtcag gtagatgacc gggacatcct gccggcgctg aatttgaaga
    11101 gccgtttcga cgccgtccat tttccctttc agcacaatat ccatcagaat gagatccgga
    11161 tgcgtgtcgc ccgctttgcg gatggcctcc tctcccgagg ttgccgtcgc cgggacccgg
    11221 tacccgagcc gctgcaaact gagttgaata tccttcgcca caaccggttc gtcttctacg
    11281 atcaagatgc tggctgcgtc catggcgtca taccctttct gaatattgca gttgctggaa
    11341 gcggattcgc cattccgtgc ccgagccgct tcggagttcc gtatggccgt ccagtttctc
    11401 ggccaacagc gtgaccagct ccaatcccag cgaatcggga ttgttcagca ccccatccgt
    11461 gggaatgccg atgccgtcat cgctcacaca caaggtgaat gtcccgtcca catggtccaa
    11521 gagatcgata tgcacggtcc cgcggccgct ctcgacgaac gcgtgcttca aacaattgga
    11581 caccagttca tcgatgatca ggccgcacgt cagacccgtg tcgatatcaa actcgacatc
    11641 gtctacattc aactccaaac tgatgagtcc cggatcgact ccgtaggaac ggaacagatg
    11701 cccggtcagg gtgcgcgtat aatcgcccat cttgatgcgc gagagatcgt tcgaacggtg
    11761 tagcgtttca tggagcagcg cgattgaggt gatacggacc tggcactctc ggaacaactg
    11821 attcaccacg gggtccttga tagaggcaga ttgaagattc aacagactgg agatgacctg
    11881 gagattattt ttgacccgat ggtgcacttc ccgcagcaaa ctctccttct ctttgagcat
    11941 gcgccggagt tgatcctcca tatctttgcg ctcggtgaga tccatgcagg tgccgatata
    12001 gccgccgaat cgaccatcct cgtcgaacag tggcacaccc gtatccatga tccatcgata
    12061 ctccccgtca tggcgccgta ggcggtactc gagaaagaac ggctgttccg acttgaatgc
    12121 gtccagatag gacttccggc aacgctccag gtcgtctacg tgaatgccgg taaaccaatt
    12181 gtcaccgatc tcttcctgca tcgtgcgccc ggtgaactcc agccaccgtt tgttgataaa
    12241 ggtaatatgc gtgtccggtc ccgccatcca caccatgacc ggagccgtgt cggccatcat
    12301 ccgaaatcgc gcttcgcttt cacgcaaagc cgcctcgatg cgttttttca ccgtgacgtc
    12361 gcgcgcaata gccgacgcac ccatgacgca gccatcggaa tccttgacag gcgagatcgt
    12421 cagcgacaca tcaatacgct ctccctgttt ccggcgctgc accatctcca cattgcgcac
    12481 atgctcaccg cgagcaatgc ggtccaacat cgtcggcact tcatctaatc gattgggagg
    12541 acagagcacg gaaatcggcc gccccaagac ttcctcggca ctatatccat agacccgttc
    12601 tgcacctcga ttccaacttt gaataatgcc ggtcaaggtc atgccgacga tagcgtcgtc
    12661 ggacgatttg acgattgcca ccaactccga caccgcttcc gcacgaagga cctcgagctc
    12721 ttgattggca gccgccagat ccgaggtgcg ttcctgcacc tgctgctcga tatcttcatt
    12781 gatgcgcagc aactccgcct cgtcgcgctg gcgacgcaga cacaacaagg ccgtcaccca
    12841 gatcaccatc aaggcgaagg ctcgattcac ggcgctcacc cacgtcaacg cgtaaagcgg
    12901 gctgtgaaac aggtccagga tcgtgacaaa ggacgcggtc gcagccaccc agaatgtgag
    12961 acgtggatac ggaatgcgag aggcaatgag gacaggcact acgtagagcg tagtgatcgt
    13021 caatcccaga ggcagccacc aatcgatggc gccgatcacg gcaatcaatg ccagcgccac
    13081 gcccagaatc gaatagctgc tgcgggacat gcccagaaag tatgaagaag gaattgtcat
    13141 aattgtaacg acgccgtttc acgttccctc tgggtgtagg agcaatacct atgccttcca
    13201 actcacacgc ttcataacgg catgcgtgaa cacgtgctgt cgaggaaagg tacggacgta
    13261 cagacagcct cgccctgctc ggtgcgactt cccggctaac catgtatccg cgacaggcgg
    13321 caggtgaggc gtttcacgca gctagtgcag cgcggctcgc ctccccgggc cacatcttct
    13381 gggagattcg ggtgtacacc tctgcctcat gaatgttcag acttgaacgg cgcgcgattc
    13441 gtgcggttgt cgtccattca atgactgatc ggagtggcgc actaggcagg cacaatcatg
    13501 cggttgccca cgacgtatct gtggagagaa ggcgttgcgg ggcctgcgca tggacgacac
    13561 atgcacgaga ccctgcggcg ttgaggagat cgaggatcgg ccgacggaac aggccgttgg
    13621 agtggaacgc gatcgacgct ggcgaagtct gccggcgtta tcgtttacgg aaaaacgcgg
    13681 caatcatctg cacgacgtac tgaagctgct catcggtcag ttccgcataa atcggaatcg
    13741 acaacacttc ttccgcggca cgctccgact gcgggaaagc gcctttctgg tacccgagat
    13801 cgcgataaca attttgcagg tgcagcggca atggataata cacttccgtt ccgacgccat
    13861 gatctttcaa gtaggcccgc aattcatcgc gcttcctgac acgtagcgtg aattgattga
    13921 agacatggaa attatgagga tgcgtcacag gcagagtcac atgatcggtt aattgtgcgt
    13981 cggtaaataa ctggtgatat cgcgctgcat tccggcgacg cccatcggcc cattgatcga
    14041 gccgttgtaa cttcaccaac aagacggctg cttggagcgc gtccaaccgg ctgttgatgc
    14101 cgatggcttc atgcacgtat cgcacacggc tcccgtggac ccgcaacatg gcgatggatt
    14161 cggccaactc tttgtcattc gtcgtcacca tgccggcatc accaaacccg ccaagatttt
    14221 tcgatgggaa gaaactgaaa caggccaggt ctcccagcac gccggcgcgc ttcccgtttt
    14281 gcgcagcgcc gatcgcctgg caggcgtctt caatgacgcc gatcttgtgc cgtcgcgcaa
    14341 tgtcatgaat ggcgcccatg tccgcacatt gaccgaagag atgcaccggg ataatggctt
    14401 tggtccgttt ggtgatgact cgttccagca acgtcgggtc catattaaaa tcatcgggac
    14461 ggatatccat gaagaccggt ttggcaccca ggcgtgaaat agcccccgcg gtggcaaaga
    14521 aggtaaacgg caccgtgacg acttcatcgc cggctttaac acccaacgcc atcaatgcca
    14581 gcagcaaggc atcgctgcca gaagccacgc ccaccgcatg cgtgctactg acataggtcg
    14641 ccaccgcctg ttcgagcgcc accacccgcg gccccaggat aaagccctgc tcatcacagg
    14701 tcgcttcgat cgcggccaga atttcactgc gcatggattg gtactgggct ttcaaatcaa
    14761 gcagcggaat attcatcgtc ttacccggtt tcctctttac aagcgattgg gctgcaattt
    14821 catcacatcc tctgccggcc gcgtggcgtg caggagatac gtgtagagcg agtgatactg
    14881 tttaattgtt tcttgaatcg taaactcttc cggcaactcc tgcgccccgt tccggagatc
    14941 cgctcgaagc cgttcgtcac ccaggatttg acacacacga ctggccatgg ctttgacatc
    15001 gccagccgga cagagggttc cctggatgcc ctcaatgatc gcttcggcgg agccccctac
    15061 tcgcgtggcg acaatcggaa tccgactggc cctcgcctcc agaattgcgc agggcaaccc
    15121 ttcccattga gatgtcaaca cgaagacatc aaacgccttc agcaatgagg ccacatcgcg
    15181 ccgccagccg agaagactca cccgatcctg cagcccttgc gcttgaatca tcgcttcgat
    15241 ctgcggccgc agtgcgccgt ctccggccag cacacatttt gctgctggca tgcgctgaca
    15301 gacgagcgcg gcgacgcgga taaagtcttc gggagatttc tgcggtttca aacacgagac
    15361 tgttcccacg aggagctgct ccggccccac tcccagcgcg gctcgcagac ggtcgcgctc
    15421 cgcctgctca atccgggcgg caaatggcgt cggatcaatg ccaggccgga ccaccgacac
    15481 cttggaggcg ctgaacagct cccactcgag tccctgtcgg cgatcagcct gggagactgc
    15541 gatccaatgg gtggtcactc gtccgaccat ccactcaagc ttgatcacca gatgttgaag
    15601 ccacaacggc tgggcaggtg tcacaccata cccgtgtatc gtgtgcagga tacaggggac
    15661 cccggcgagc caggcggcca accgccctag gataccagct tttgaactgt gggtgtgcac
    15721 aatctttggc cgcaagcgtc gaaacgtcgc gaccagttca aacagcgcct gcagatcttg
    15781 gaggggatgg acttctcgaa cgagcgatgg gatcaagcgg acatcgacac cttccagcgc
    15841 atgcgcttcc tcggtcagca agccgccggg gccggcaatc agcaccggac ggaatcgccg
    15901 acgatccagg cccgacacca cccgcatcgc cacttcctgt gcgccgccca gctcaagttt
    15961 ggtgatgacg tgacagatta catccatgcg attgacgccc tcaggccgcg gccctcattc
    16021 gcaaccgcat ggcaagctgc tgcccctggg caatcgcgtc ttccatcgac gtgtgttccc
    16081 acaatccata tctcccgatt gacgaaatgc cgcgtcgctc cagctcagcc aacaactcct
    16141 tcacggcgcg gctgcggtac cgatcgaaca acacataggc gtaatacaag tccttcacat
    16201 ccgacatgac cagctcatct gtcggctgca gcacgcccgc cccttccaac ccacggcgga
    16261 cccgttcgat cagcgatgtc tccgattctt tttccgtggg ctggtgcgaa atctctacat
    16321 acagagagct gcaccctggc tgccccatgg acggagagaa attcatgggg aacccggcac
    16381 ggtagaatgg gtaccggtgc tccggaaaat aaatccaatg cttatccgac acatgttccc
    16441 gcgccacggc cagattgacg ttatagaccg acacccaccg cagcgcgccg gccagctccc
    16501 gcatcgacgc tggaagatcg acgcaccggc gcaccagctc gggtaaagga atggtggaaa
    16561 tgatacggtc atactcctca atgcgttccc cctgcgcact gcgaaagacc gcgcgacgcc
    16621 tccccgtttc gatctccacc agttcggaac cgtacgtcag gttctccacg gagggcagaa
    16681 atgcctccgg caacaccttg atgccgccgc tcaccggata ctgaaacgac gggttgtagc
    16741 cgaaagcctt gtccttaata cctaaggcgc cgctgacgac gtccttgaca tccggcttcg
    16801 gcacgagcca ggacacccag tccgaggtga gctcatcgag cggcacctgc cacaattttt
    16861 cattaaaggg caccatgaaa tgtttggcga tcccttcgcc gagactttcg atgatccatt
    16921 gtttgaacga tgggttctcg gcgggcggcg tcgatggcga ccgtgacagc gtggcgatga
    16981 atcccagcag gcactcccgc accacctcgg gaggaaggcc gtacgtgttg acctgaaacg
    17041 gatattccgt ataggtgtca tgagaaaaga caaatgattt gcgcgcatgc cgctgcaacc
    17101 ggtcgggaag caggctttcg accaacgcct taatcgcggt ctggcgaaaa tggagcagat
    17161 gtccggtgta gtcaaaggtg aagccgtctt tgacatacga gcggcaaagt cctccgacct
    17221 cgcgctcccg ctccagaatc ttgtacggca tgccgcgcaa gtgataggcc gcgctcagcc
    17281 ctgccaatcc cgccccgacg atgacaatca tactgcgccg gtcctttctg tcgaacgtgc
    17341 cgggacggcc tcagggctca ccgccacgac cccgctggac acattgactc gcgtcagagc
    17401 cacagcagcc gcggccagac acaacaccgt gacaccgctc aagatgaggg caaggtcctg
    17461 cgggacggcc atgaccagca gcccgatccc gcccaagatc gccgccccga gataactgag
    17521 caacacgacg tgcgtgaccg acaaccccca atggcgcaac cgaatcgcga tgtgatcggg
    17581 actgccgagg aataccggca atccgcggag gaatcggatg tacatgacga acagcgtgtc
    17641 gaaaatcggc atgccgagga tcaagaccgg cgtcagcaac gagacggaat ggccctgcgt
    17701 gtatttgcca atcatcgaca atgcgccaag catcaagccg atgaacatcg cgcccgaatc
    17761 ccccatgtag atggaagccg gccgccagtt gtagcgaaga aacccgagca gacttcccat
    17821 caaggccgcc agcatgaacg caatcgtctg atcgccgttc agaatggcaa ccacgcacag
    17881 aaacgcggcg ctgatcacgc caaccccggc tgacaatcca tccatgatgt ccaggagatt
    17941 aaaggcattg atgatgccga tcatccagaa caccgtgagc aggatatcga cccaatcggg
    18001 aagcgatgca atctcgatac gaatgccgct cttgatcaac acgaagaccg ccaggaactg
    18061 cccggccagc ttcgtgcccg gcgacaacac accgaagtcg tcgatcaatc ccagcatgac
    18121 gatcaacgtt cctgagagca cgatgccgag cacgtcctgc cggaattcga aggtaaacgc
    18181 caggctcacg agaaaggaga ggtagatcgc caatccaccc aaatagggca ccggctcacc
    18241 ctggtgcttg agccgaccat ccgggctgtc gacaatgccg aattttaacg ccgcacggcg
    18301 cgcgataggc acgccataga cggacaacag caccgcgacc aggaatgtca gtgccaggag
    18361 gatcatcgca tacctgtgga atggccatgt cctcgcacag aaagaccgac aggccgcggc
    18421 atctgacggc tgggcgcatc ctcggcaaac gcacgataca catcggcgag cttaggtccc
    18481 cataccgcca aggagaaccg ggtctccacg gtccggcggc ctgcctgccc catgcgagca
    18541 cgcaattgcg gatcgcggca caatgactca aggcgcagat accactcttc ttcggtcgag
    18601 gcgagaaatc cattgtcccc atttacaaga atgtcgcgat tgaccccgac aggcgaggcc
    18661 accgccggca atcccaccgc gagatactgc agcaacttga gcgcacattt gccccgggcc
    18721 cactctgtat cctccagcgg catcacgccg atggtggcat cctggagatc ctcaacttca
    18781 cgccgccact cccaggatcg aaactcgacg tccaacccgt cgagcaccgg tggctgagaa
    18841 caaacgacgc gaagcttcac gcgatagcgc tcttgcagcc ggcggattgc aggcgcaagc
    18901 acgttcaaat atttgaggtt gtaagccagg ccgatccaga caatcgtgat agggtcatcg
    18961 agcagatggg atgcggcggt cggtcgcaag ggcctcggag caaatcgctc agtgtccacc
    19021 accgtaggca ccaccgtgac tttagaggaa tattgggtgg cgtaggcggc taaccgatcg
    19081 tttcccacaa tgacgcccgt tgccatcctg aagagcacag gcatcttccg ttcatggcca
    19141 cgagtcaggt aaatcgcgtc atccatctcg atgaccaaac gatagcccaa ccagcacaac
    19201 aaccgttcga ccagtggagg cgcatacgga aagagttgcc cttcgatgac gatcaggtcc
    19261 cgttggccca gcatcatgag cgttccaagc cgtttgagaa agcgcgccac gacatacgga
    19321 atcttcagaa cggtctgcag catcaaggag cgaatgtgga gaatcgaaaa gtaggtggga
    19381 ccgaacagcg gctccacatg gcactcgatg cccgcattgt acaaatgcgg caagtattga
    19441 tacacgcgat agcggctgct ggggccaatg ctcgagctct tagaaaaata ggtgaccgtc
    19501 atggcgcgcc gtttcgcccc gttgtctcgg aatatccacc ggttgcgcag gcggaaccgg
    19561 ctagtcaaat agtaccggag ttctccggca aggatagatt tttcgctgtt tttgacgggg
    19621 gcagagaggc tcgatatcgg ccgcgggcct ccgatagccg tcctcccggt tgtttagaat
    19681 ttcgcggggg gaatgcggcg gaaaaacgaa tgatgccatt cagccagcat cacaagtgag
    19741 aataacagac gctcattcgg acgatcagaa gtcagttgtc gttcaaccag agtggcggca
    19801 gcgttcccat cgaagacagc aatacgctgc aggtcaaaat attcatacag gttctctact
    19861 cttcgtaacc attgcttcaa ccatgtcgcc atcgggagga caaatccctg ctttcttcgg
    19921 tggacgattt cgggcggcag cagtcgcgcg gcgacctcac ggagtgcgac cttgctgcgc
    19981 accggcgtca ttcgactgga ttcaggcagc cgaagcgcgg tctcggccac taccggcgac
    20041 aaaaatggcg cgcgcccctc gagactgttc gccatggcca tgcgatccag tttcaccaga
    20101 agatcatcgg gcaaccatgt caggacatcg gcaagggtgg ctcgctgaag accgttcgcc
    20161 gactgttgga gcgtggatcg caacgcctcc tcccacggat cgcgatccgg cgcatacccg
    20221 ccaagtagct gccgccggcc agccgtatcc atgacgagcg gaaaacctga tggcgtcacc
    20281 ggccatacgt tatcgcacag ccgttgaagt tcatccgctg gacctcgccc catcacccag
    20341 gctttcaggc atgcacgcca cgaccgacgc gacaacagag caccgtaata ctcataccct
    20401 gcaaagagct cgtctgcacc ttccccggac aacacgactg ttacatgccg cttggcttcc
    20461 cggcagagcc aataggtggg gagcaatgcc tgatcgccga gtggttcatc taacccgtct
    20521 atgaccgagg gcaacaggtc gtggaaggcc gtctcatcaa atgtgaaatg atggtgtgag
    20581 gaaccgatgg cacgtgccac cgcctgagcg tgcggcgatt catcgtaacg cgcatctttg
    20641 aaacccatcg aaaaggtatc gattgcggga tgatgcttcg cggcgagcgc cgcgacaatg
    20701 gaactatcga taccgccaga cagaaaaacg ccgacgggga catccgcgac caaccggctg
    20761 gtaaccgcag cctcgattcg accaacgagc gtcccggtat cgactggctc aatcggcccc
    20821 atcgcggggc ggtaataccg gtcgtggata atctggagcg aatcaagcga gatactgatg
    20881 tgttcaccgg gcaggacgcg ttgaatccct ttaaacatcg tacggcggcc cggcacgtag
    20941 tgcagcgcga ggtaccggtc gacactaccc gcatcaatgt cacgatcgcc ccagggcaac
    21001 catgccaaag cggtcgtatt cgagctgtac gcaaacttgc cgtttgcgac gctatagtag
    21061 aggggttttt ctccgaaccg gtcacgggcc agatgcagct ggtgattacg ctgatccaga
    21121 atggcgatcg catacatgcc atcgagtcgc gctaacagtc catccatgcc ccaatgatca
    21181 tatccgtgcg ccaacacctc agtgtcgctt gccgttcgac attccacacc acgttgtgcc
    21241 agctcccttc ggagcgcagc atggttatag atttctccgt tctgaaaggc tacgacttgg
    21301 ccgtctcgac tgaaaagtgg ctgtccgcca ccttcgacgt cgatcaccgc taaccggcgc
    21361 atgcccatgg cgatatgcgg gtcaacgaac cgaccttcac cgtcgggtcc acgcgctatc
    21421 atcgttgcca gcatacgcga cagcacatgg tgtgcctgct ggggctccat gcgatcacag
    21481 acgccgacaa tgccgcacat gcgttgatat ccctggttat gctgctcgcc ggctacccgg
    21541 cacaggtttc tggcagatga ggaacacgaa gtctgacggg agcacgttgc ctttgatcag
    21601 gaggtcttcc agcaggagga tcaatttcac aatcgaatca aagtcccgct tcccctgatt
    21661 cgccaactca gttcgtagga gcgggtacaa ttgatggagc agcgtgccgt tataaaagcg
    21721 ttcgtaacgg acatcgaagt acttcttcac cagcggatat acgtcagctg atcgcacggc
    21781 ttctgacgga tcgcaggcga gcatattttc tatggtcggc ctttcgaatc tggtattcct
    21841 gccgtcccgt aaataggcgg gatcgagcac gtttagtacc tggttcgcaa tctcaatctg
    21901 ccggtcggtc cactgaaacc gatttggccc gatgaattcc accaccacga aatacccgtt
    21961 cggcgtcaag gcgcgctcca ccgttgagag gagcgcctcg agattggtcg tatgatgcag
    22021 cgcgccggtc gaaaaaatca gatcgtactg gtcctccagt tgcagcgcgt tgacatcccg
    22081 cacctcaaat cggtaacagt ccgccggggc tccggcctcg gcaaacctcg ctgccgcctg
    22141 cttgatcgcg ccttctgaaa tatccacccc gctgacgaaa cgcaccttgc ccgatgtgta
    22201 cagttggatc tcgtgcgccc cgtctccaca acatacgctg agagagcgat cgaacgtgcg
    22261 ttgggcaaaa tagtcattca ggagccaccc caaccaatgc cggggagtat cggtcatcaa
    22321 tctataggtc gcctcttcaa ccagcttgtt attgagccag tacgaattgt ccactcgcat
    22381 cgcttgaaac tgttgtcccc aatagtcgga tacccggtca tgatcgttcc cagggtggcc
    22441 ggagccagcg ggttcagcgt ttccagcaga gcggaagccc gcacggagcc tcctcagcag
    22501 gggcaccagg cccagccgcc tcatccccgg aagcaacatg ctccgcaatc gctgctccat
    22561 gaaacctgcc tccatcatcc cctaaatccc actcacaaga gacttatttc gtcctgtccg
    22621 gcattttcac ggagcaaccg cccgcttccg gcacgccccc aagtggcagc ccctggctac
    22681 aaccattatt gagggcgccg gccctcgaaa aaaaaccctg ctgccaaggt agttcgcccg
    22741 gcctccccga gtgcgtcatc gaactcccct gccccggcct ccaactcttt tcgccacttg
    22801 gcgattgtgt tacgccactt tcttgatgtg atgaacggcg caatcgcgtc gaattgcatc
    22861 aagagactcg cggagggatg ttggtagctc ttgatcccgc aacggatttc ctcaaaggga
    22921 gccatcactt tccgcaagcc atgctgggtc atattgaaga aatgccaagg gtctccgtgt
    22981 aacggctgca tgaaggcggt gtcgagatga atgatgccac ccgggcggag aattcgacag
    23041 agctcgcgtg ccgtgtaatg cggatcctca aggtgctcga acacggcctg actcaccacc
    23101 gcatcgaacg agtgatcgcg aaatggcagt cttgcccgcg tgcagaccag atcggtccat
    23161 tcatactgaa ccgcatcaag gtacactaca tgcggacgca acaattcttt cggcgtgtgt
    23221 ccggccccga aatccagtac caacccggcc cggtggcgcc ccaggatgtc gagcacatcg
    23281 gcagaatagg gatgagtatt cgtctgctcg gtgacatgaa ggcagggcgt tccctgctcc
    23341 tgaagaaagt gtggaacgcc ccccttgagg ggcacgagcc tggcacaacg agggcacatc
    23401 cagccctggt cctgcttcgc cagaggagac cggcattccg ggcatacgag aagctcaaac
    23461 agattgaacg accggtcccg tataacgggc gggcgatacg gccccaccgc atatgtgcgg
    23521 cgaaataatt cgcgatcctg ccctgccgca tcgagaacca cgacctcaac ggcttgagct
    23581 tgctcctgct cccccatcaa tagatcgcct tgaaacccgc tgatgatcgc ttgcgaatga
    23641 gtcgaataga cggacgacac atccgggcgg acacttcccc actccagcga cgccgctcgt
    23701 tttccattac aggccacgta caactctggg cggcgaccat ggtctggaat ataccaacca
    23761 gaaaaccggt tgatcgtatt caattgcgga ccgccgggcg tctccagatt gaaccgtacg
    23821 gtcatgataa cggccctccg ctcagccacg cctcggcaaa gatctctgca tagctgctca
    23881 ccatttcatc aaaatcagtc ccgagcgcca ggacgctggc actcttcgag gctaaacgag
    23941 cccgcagtgc ctcgtcctga agtagacgcc gaagtcgatc agccagggcg ccgctatcac
    24001 ccgcttcata aaacaaagca ttcactcctt ctcgcacctg ctcgcgaatt ccaaatacgg
    24061 gagtcgtcac aatcgggaga ccataggcca tcgcttccaa taccactcgc gggtaacttt
    24121 cgagctgcga tgtgcacaca aacaggtccg cagctcgata atatcgtgcg gtttgacgcg
    24181 tttctggaac gagatgcatc cggctcctca actctgacgg cagttgcgca acgagggcgt
    24241 gcaatcccgc gctgtattca cttggccggt cccctacgat gtaacagcga acccgcttct
    24301 gcagatcggg agacagttga gccaaggctt tgacaagatc ttgttgcccc ttcctgggac
    24361 agaccgttcc caggagtagt atcaccacct cgccatcaca tgcgccgatg gactgacggg
    24421 cctgtgcagg aagccattct tcgctcgtct gttgaatgcg tgtctggtcg aggccgttcc
    24481 gaacgacggt aaaattgtgt ctcgtattga gcgccgcata ggcgtcgcgg gtggcatccg
    24541 cgacaaagac cacgcgatat ggcgatgcaa aacaatcgta ggctttttga atgaccccgt
    24601 caggcaaata atcaaaatat gtctgccagg gctcgctttc ccgaggattc catacggagg
    24661 ggatgccggc gatctgcgca gcagcgacgg cgtaaaaact ttggagcgtg ttggcatata
    24721 tgagttctgc tccccacgac agacacttcg aggagaagac tttcacggct tcctcatatt
    24781 ccttcagcgt cgtcacaccc cagagcggat gccgatccac catgaccgga atgccctctt
    24841 cttcatacag ggaccgcaac ggaccatcca gaggggaaaa cacaatgggc tgaatgacct
    24901 tccgccggac cagctccttc gtcaattcgt attggctcca cggggctccc tcgcagttca
    24961 agcttaaggc ggtcatcacc atcggaatcg gcttctgtcg ccgcgctgcg acggcgcgcg
    25021 gcacgaggtt gaaactctca tcgaccaggg acaaatgcgg gctataccag gggtcctgcc
    25081 gccgtttgta cttctgctta aacgcggcaa cctcagcagg atcgtcacgg aatcctcttg
    25141 aataaccctc atagtgcatg agttgcgcgt cggggcagta aacgcagcga tatccttggt
    25201 cgaccagccg atagcagtag tccacatcgt tataagcgac accgaactcg gcctcattga
    25261 aacctcccac atcgagaaag cgccggcgag atgtcaacaa acaagctgcg gtgacggccg
    25321 aataattccg cacaaccgag gcataggcca aataaccgtg ttcccacgag ggcgtcagct
    25381 tgaaggcggg accggccatg ccatggtaaa gcccatggat gactccagca tgctgaatgc
    25441 gaccgtccgc aaagatgagc ttggcaccaa ctgccccgac ccctggcatt tgcgcgtatc
    25501 caaccatttg gctcaaccag cgtggggact tgacctccgt atcattgttc aaaaacagaa
    25561 tgaactcacc ggtgacttgc tctacggcgc gattattgat ggcggcgaaa ttaaaccggc
    25621 cggaaggatt accaagtcga atgactcgat ggggaagcga gtgcagatac gccaacgtct
    25681 cagggtcgtc actctcattg tcgatgatga cgatctcgta ctgtcgatag gtggtcgcgc
    25741 gaagtgattc gacgcattga cgcagcaccg tgacctgatt cttggttgga atgagaatcg
    25801 tcacggtcgg tccatcatct ggaaattcgt gacaatagat ccccaggttc cctgccgccg
    25861 caaattccgg ttgcgtcacc cgcaccgcaa tgcctcgtcg ctcaaatgct tcggcaacag
    25921 cccgccgtcc tgcctcaatg ctggcaggct tcgctgcgcc gctggaggcc gtcgagcctg
    25981 gcaacgcccg ccagtgatag agcactttcg gaatatgccc gaccatgccc gtccgctccg
    26041 ccacccgcaa cgcgagatca taatcctgag cgccttcaaa tccctgcctc atagcgccca
    26101 cggtctcaaa caacgatcgt cgcacgacga agatatgact catgtacatg taggaaagca
    26161 gcaactccgg cgaccaatcc ggtttgaatt gcggcgcata ccgctttcct gccgaatcga
    26221 tcttgtcatc atcagaataa agcgcatcaa tctcagggtg ttccgccaga tacagtgccg
    26281 cttcgccgac cgcatccggc gtcaactcat catcgtgatc gaaaaacagc aaaaattctc
    26341 ctgtcgccag atctgcggcg cgatttgtgg ctagactgat attgaggttc cgctccaggt
    26401 aggtgagacg gatacgaggg tcttccgcgc ggaaccgctc caattcatct cgtatggcag
    26461 gattcgtact gcagtcgtcg gcaatgcaga gttcccattc tccgcacacc tgcgcccgta
    26521 ctgaatcgat ggctttggtg agacactcaa gtggggggtt atgcaccggc ataaccagcg
    26581 aaatcgtcgg caaacggccg gcatgccggc tcaatcggtc gagtaaatcg tcgcgcattc
    26641 gccggttcca gacattgacc ttcagccagg cgtcataggg agggagtact ggctcgatgg
    26701 ttttaggagc cggcgagatt cgttgcgcga ggattttgaa tcgaaagaaa gctttccgga
    26761 atagatcggc acattcggct ttcctgggca gtcgaccatg acgcttatac caccggagac
    26821 cttcgacgat ggcgaagcgt gaaaaccgaa tggctttgat caatcgctgc atgagacgat
    26881 tcatggctca caacaaggcg gtcggcaaga cgccagttac tatgcctggc ccaccgcgcg
    26941 ataacgggat cgcgcagtct gaatgtgtgc atgttttcat gcgcggcggc tcttctcgac
    27001 tcggttcccg ctgacggctc gtagcgcatt cgccacggcg cgaagcggtc tagtcgcttt
    27061 ccaggaatgc gaattcatca tcagttcgat ggccgccttg agccctgcca cctcttcttc
    27121 cagtcctaga attctgcgac cggcatgctc aagctgatgt tggagcgcat gaatttcagg
    27181 atctgactcc ccggcctgtt caaacaagct ggacaacact gggggcaagg ctgcatccga
    27241 ggcgatcgcc acttggtaac agggccgcac caatccgctc gcagcctgaa tagccgaatc
    27301 tttgtcgcgg gagtaatgaa ccgcttcccc cggcgcccct tgcggtagaa ttgccgaggc
    27361 atacagcacc cgctggccga gcatggccac acgattgaag tagcgctcaa cgagtcgctg
    27421 gaattcttcc gcatagagct ctttcacatg gtaggcattg gcgtgaccgg agcgttccgt
    27481 gtattccagc ttatccggac tggacatcac cataaccccg cccggtcgca aaacacgttt
    27541 gatttcggca aacatggctt catgctctgt gtggtgttcg atcgtctcga aactcaccac
    27601 cagatcgacc gcacagtccg gaaggggaat attcgcgcat tcaccgacca ggtactcgag
    27661 attgggtcgc tggtagatag ctctggcatg ggcaatcgca tccggcgcaa tgtccactcc
    27721 gtagacgcgg tcggcagtgc cggcgagcac ggcagagccg tacccttcgc cgcaggcgat
    27781 atcgagcaca atttttccgg cagcgcaatc cttcgccaag gcatagcgat gcaaatgctc
    27841 cagtgcgatg gttccctgca tctcaggaag aaatcgctct ccggtcgctt cgagttcagt
    27901 tgattcattt actgtcttgt tcaccactga ccccctgtta ccggtctgga ttcggcaacc
    27961 tctgcaatga gcgcaattcc cgcgggatac cgatagggca cgatccgaca ttcatcaaag
    28021 ccgctctcca agacctgaca ccacacgtct gcgccgaatt ctgtatgtac agtcaaggcg
    28081 gtgtcgatgc acccttcgct tccgtgcaca ctcagcggca acccttttct tccccgcgtg
    28141 agccttccca ccaccacagg taccgtaaag agacaggctc ctcctggacg aaggacccgg
    28201 cggcactccc gcaatccttt catcaggtcc ggcacatgtt ccaaggtatc ggaatggagc
    28261 acgacgtcga atgaacggtc ttcgaacggt aaagccatca tgtcgtactc gggataccgc
    28321 accaggcgat gccctggaag cgtcgacagc gtgccggtca acgatccggc ttcattgatc
    28381 tccaacacat cgcatcggcg agccaccgga gtatggaccc actcttgcaa tgtggtcgtc
    28441 gcgcgggtcc atcgcaataa ggcatcggcc agggcgatgg agcgcacatt cgagccacag
    28501 ccggtgcacg cggttccctg ctggacgttg atgtagtcta cctcacgcga tgagaggccc
    28561 cactgggcaa tgaggtcacc ccataacacg tcatgatgag aaaaggtgct gccgccacac
    28621 accttacaag gcaatggaat catggaggcg ttcatgttga gcatcctgtg cttcgatttc
    28681 gcagatctgt gtgcgcatta cttctacggc gatcagacca aaacaccatt cggaaggagc
    28741 agacgtgaaa gccaacgcat catgaatcca atgttgctgg acatgctcct cctgcgttcc
    28801 gtcggcaagc gcgatgctca tggcatagtc gcccggatgc agcaccggca tgacaaactc
    28861 cagttcagcc acgaagcgcg tacccggact aacaccgtga ccggcagcat ttcccgcggc
    28921 acacgtattc gcgccgaaca gagactgccc gaagcggttg cgcaccagga acccaacgat
    28981 cggacttgcc aatccgacgg acgtgacgca acagacacgc agcgtcacct gctcacgctg
    29041 cgtgacggtg tgaaccgtgc gaccgttggc attgcacaag gtgatggttt cgatccatgc
    29101 tggccggcta tgcgatgccg atctcgtctc atgatgtggt aataccgcca agttcgacga
    29161 gtcattctgt ataggctgag ccggatccga ggggtctgat gacggaagac cttccgccac
    29221 cttctcccgc ggtatttcca taggggtagg ctgatgcagg tatccatcac agatcacctt
    29281 tgcttccccc ttgcccgcga tccgtccgtg ctccagccac aaggccgtgc gacagaggct
    29341 taggacggct gctgaatcgt gactgacgaa caacaccgtc ccccgttcca taaacgctct
    29401 aagaaagcgg atacactttt gaacaaaaaa tgcatcgcca acagccaacg cttcatcaat
    29461 caccaggatg tcggcgctga catgtgccat cacggcaaat gccaggcgga caaccattcc
    29521 actcgaatac gttttgaccg gctgatcgat cgatgacccg atgtcggcga acgccagcat
    29581 gtcatccaac cgggcatcga tgtctgcctg ggacaaaccc agcaaggtgg cattcagaaa
    29641 gacgttctcg cgccccgtaa actcaggatg aaatccagcc cctaattcca ataacgcggc
    29701 gatgcgtcca tcggtctcga tcgtgccgct cgtcggactc aacgtgccga cgatcaattg
    29761 gagaagcgtc gacttgcccg agccgttccg tccgataatc ccaagcgttt cccccttctg
    29821 cacctcgaag gacacatcct caatggcatg cacttcgcga tagtatcgtg aaggagactg
    29881 cccaaagcat ttctgcaatg gtggaaggat ccattgtttt ccacgatcgc gcgggcgatc
    29941 gtacacgcgg tacgtcttag aaagttggcg gacacggata gcccactcag aggacatcgg
    30001 caaacgcctt ccgtgtcttt tgaaaccaga ggagcccgca ccaggcgatc agataacttc
    30061 ccgcacaata gagaccgata ccgatccagg atggcggcct gccccaaatg agcacatcct
    30121 gagcttgcgt gatgagaaat gtcagcggat tcgcatacag caagatccgg taggcctcag
    30181 gaaacgcccc agcgggataa aacaccggcg acagaaacag cataacggtc gtcaacggac
    30241 cactcgcctg accaatgtcc cgcacaaaga ctcccgcgga tgctagaaac cacgagatac
    30301 cgatggtcac cagagacagc ggcagcagga gaagcggcac cagcaacatg gtccagtgca
    30361 ggtcatgatg cagaaaccca taaaacgcga tcagcacaag tgcgctgatc aacgcatgga
    30421 acaacgccga accgagagat gtccacgcca ggatttccag ggggaagacg atttttttga
    30481 cgtaattgct gtgattgacg atcaagtagg gcgcccgatg aatactttcc gcaaacaatg
    30541 catggacgat caggcctgag aacagcagca gtccaaaatc gagcgcgctc tccccgtcct
    30601 gtccccaccg cattccaaaa gcgcctcgaa agacaagggt atagaccgtg agcatgacca
    30661 tggggtgcag gaatgcccac aacattccca ggagtgatcc tcgataccgg ctggcaatct
    30721 cccgcttcgt caattgacgg atcagattcc agtgcgcgga catgctcgtg aggacgatca
    30781 agggggagag gccgtaacgc tggaagacca tttcttaccc ttcagtaaga gcgcggcaac
    30841 aaatttccaa gactctgggc gacacgcaca tagccggtag ccgacaggct ccatggctac
    30901 gatgaaccac gcctctctcg cgatgactta aaaatcccgc tgctgaaaca ccaggcaggc
    30961 ccccgtcagc aagagactgg catacaacag gccatacagt gacgcgagca tgagatactc
    31021 cggagccacg acaagaccca ccgccgcttg ccctttgatg ttgagcattt ccagatttgg
    31081 acagaggtag tacaacaggt ccactactcc cttcaccgca ccgctttcac tattggccac
    31141 catcgatcgc aggtcagccg tgagatggcc gatgacatag agacccagcg taaaaatggc
    31201 gctcaatgtg gtggaggtga acgtcgaaaa gaacagcgcg atagccgtca ccaccaggat
    31261 ttccacaaag atcagcgcga cagcttggaa aagagacgtc tgaatcggca catgatagag
    31321 ccagagcgta agcagaaaca ccgccagcat gatggccaga ttcacgaaga gcgtcagtgc
    31381 caacccgaga tacttcccca tgatgaaaaa ggtccggctg atgggcctcg ccatgatcgt
    31441 ataaatcgtc cgccgctcga tttctttatt gaccaggctg atgccgacga aaatagcgat
    31501 gatcacgcca atcaaattga tcgccgccag gcccatatcc gcaatgacct tatggtgctc
    31561 ggtaatggag agatccgcca gcagcactga tagcccgatg agcaacccgg cgaacagcac
    31621 gagattgtat aaaatcttgt cccgcaaact ttcacggaac gcattgacag caataacgcc
    31681 gatcgccccc atgtcaggac gccctcccac tggtcatatg cggcaacact cgcgtggtcg
    31741 cctgcgcggc ctcttgaaaa aataaatcct ccaacgacgc tttgtgcgga gtgatggaca
    31801 gcaactgtcc accctggcgc cgaatctcgc ccacaagcgc atcgaccgca tcaggactgg
    31861 gcaaaacaat cagacattgc tgtccctgct gcagcacgcg ggtggccagg gagtgaatga
    31921 acgcattccc ctcgaccttg agctgttggc agaccacttc gaccgatcgt gtatgatcct
    31981 ggcgcaccaa ttcatcaacc cgtccgctgg ccaccagtcg gcccttcatc acaatgccga
    32041 cacggtcaca aatcatctca acatcgtgca gaatgtgtgt gctgaaaaac accgttttgc
    32101 cgcaatcgcg cagactcaaa atcagatcgc gtacctgttt tcgtccgacc ggatccaatc
    32161 ctgtcatggg ctcatcgagg ataatcaatt ccgggtcgtg aatgagggct tgcgcaagcc
    32221 cgatgcgttg cagcattccc ttggaaaact tccgcaactg tctggtgcgc gcttccacaa
    32281 gtccgaccag ttcaagaaga tcggtcactc gctgcgtgat cgccgaacga ttcaggccgg
    32341 ccaaccgccc gtagaatccg agaaactctt cggcagtgag atagtcgtaa aagtaaggcg
    32401 actccggcaa aaatccgatt cggcggcgcg ttgcgacatc ccccgccggt tgtcccagca
    32461 gcagtgccgt tccactcgtg gggcgcacca gtcccatcaa aattttcagt gtggtcgttt
    32521 ttccagcccc gttcgggccg agaaatccaa aaatttctcc acggccgacg gtgagcgata
    32581 gcccatccag agccacaaat ggaggtcgcc cgggccagcc cgacgcgtag gttttggtca
    32641 gattatgtgt gacgatatcg tccacggcac tcctccgtca ttgctgcaca gcgggctgca
    32701 gcgtctctat tgcatcggcc tgtgtcgagg gcgtcgacgc aactcctaag cggcaggcta
    32761 ctttttcatg aatacgtagt cggtcccgtt ttgaggacgc actgacgatg ccagtcaggc
    32821 catcaatttc atattgcccg cctaaaggat cctcgggaag tcgcggaatg atgccgtgca
    32881 gcatcagatc ttccaccttc gcgggcgcct ggccatactt cagccgatac cgtctgatgc
    32941 tttcttcaag aaaccggagg tcctgctctt gaacaatctc tttcattcgc cgaaacagcg
    33001 cttcgcgaac ccgatcatcg gctacgctcc gggagaaacg gtctaaaaat tctaacgccg
    33061 cagtgggatc tccactttcc acagtcatgc gtgcggctaa ttgaggaagg tacgctggag
    33121 aaccgggcac gtgcgctgcc agctgaaaaa actctccggc ggctgaggcg tcgcaccgtt
    33181 cgtagtagga gatatagccg gcgagaaacg gtagttgcca attggccgga ttgtgccgga
    33241 tacctttgcg taagatagcc acaccttcgt catggcggcc gaccaacaca ccaaggaaga
    33301 ggcccgtagc ttgataggga ggaacgaagg tgggatcgag gtccgtcagg acatctacgg
    33361 catgataggt ccaggtatgg cccaactgtg tgtcgcgctt cgcgccgata tgttggacag
    33421 cctgtagcca gatcaggtct gcgacgacct gccgataccc gagaacggcc agtttgaaat
    33481 attctccctt cgggagatac gccaattgct cggcccttgc gacagcggtc cgctctccct
    33541 ccagaatatg gagcactccc gatgtgccga tcaacaaaac caatacacac aacacatgac
    33601 tgaggcgcga cctgatgtcc gtacgacctc tcattggctt cacccggcaa ggccttttgc
    33661 ttcaacggct gcacgcaacg gcgcgacatc gacacttaaa aatgtcctgt cgatattatt
    33721 tttgttccac tgttcatatc gcgcctgccg cacctgtatt tcctgcaact cccgcctcgc
    33781 gtcatcgatg cggcccgcat cgaccgacaa acgagccagc aacgcgcgag caggaagaaa
    33841 attcggctcc aattgctcgg cttccttcgc ctgctgctcg gctaacggcc gctcgccgag
    33901 catccaatga agacgcgcct gttcatannn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    33961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    34021 nnnnnnntat cgaatgtcag ccaggccatc cctaatcgac tgacttccgc tccgaccaac
    34081 agtagcaaac aggcggcacc cattccccac aaggggcgcg actgaatcgg gatggcatgc
    34141 agggcatctg tgttgccact ggttatccga gcaactgata cgatcagtcc cgcacagaga
    34201 acgagcagga tcgcgagggc tgattcacgc aaactggagt ccagcgcggc atggacgaga
    34261 agggcgattc ctccgcctcc tataccgagg atgagacttc tctgccaccg taccaatctt
    34321 gcttggagca cctgcagaag gtcccgcatg accaggccta tggcggccag aaagaccagc
    34381 agcgcgccta cgcccatctc cactcctatt tgaagatagt cattgtgagg agtgtgggcg
    34441 acttttccgt atcgggtaat ttccccttcg accggaaacg catacaaagg atacgtatat
    34501 tggtagagcc ctaagccgat tcccaatgga tgatcggcca tctgggctat tgcgccttgc
    34561 cacatctgcc aacgggcata cgaaacaggg ttctgttcat gctcagcaag cacccgttct
    34621 ttgagcggag tggggacgat aagcgccgcg agcagaagcg cggcagtgcc catacctgcc
    34681 aacttccatc catatcgggc cgtcaggatc cacactgtgg ccgcgagcca ggccaccaga
    34741 cctccgcgtg actgagtgaa gatcattgcg atcaggacaa tgcccaacgc tgatcccatg
    34801 ccggcccacc agaatacagg cgacaccgag gaccgataca atattgcgct tttccggtat
    34861 ccgtagacgg cgatgctcaa tagaactgcc cagctgacgg tcagatagcc ggcgaggaaa
    34921 ttcgggttga aaaatgttcc gctgggtctg acgacattcc acacaacacc ctgcacgata
    34981 gtccaggcag cttctcctaa tcccatcacg atgaccatca tcgtcaacgt atgcacacgc
    35041 tcccaccggt cgacaacaga gaccagcaga taaaacaaga tggcgtatcc cgtgatcatc
    35101 accagccact gccgactctg atggacatag ggggaaaaaa tcgtggctgc gacagcaaag
    35161 cccaggaacg ccaggacgac atatctggct ccaagccttg gaacaattaa acgacctgcc
    35221 cggattgcct gaatgagcgt tccaccaagc caggccagaa tcacaagccg tatgatcatt
    35281 tgcgctggat gcgtcgttcc gccctcctga agcggcgaaa aaatcatcag cgcgcacatt
    35341 acgatgactg gcatcgaaga caggaattgc ataggtgtgt tcgcagactt gatgcgaccg
    35401 atacctcctg ctttatcaga gaccggcaat ttggcaaagt gaaagtgaaa ttg
//
LOCUS       DAOQPD010000033        35249 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_502_length_35249_cov_24.418594, whole genome shotgun sequence.
ACCESSION   DAOQPD010000033 DAOQPD010000000
VERSION     DAOQPD010000033.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 35249)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 35249)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35249
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_502_length_35249_cov_24.418594"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(271..891)
                     /locus_tag="PK063_09450"
     CDS             complement(271..891)
                     /locus_tag="PK063_09450"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97318.1"
                     /translation="MPMTGLALPVIAGIVLLSGGAETSAGRDWKTGSDTYAIREVKSP
                     SRQKAAGVTYKVVGVFQRDKQFIGGSAVADVTEQVEFEFTWPLVEGVQPKVLPNIPTK
                     VDNLRDGSAVCQAPVLKSTYEHFDLKSIAVIGTMFGLVGERRTPDMEEYVGGGGCKGT
                     HPVQGEVREEQLLVTVPPEILAGGVPKGQVLKQQDQGWTWTFTPLP"
     gene            complement(923..1873)
                     /locus_tag="PK063_09455"
     CDS             complement(923..1873)
                     /locus_tag="PK063_09455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HMZ97319.1"
                     /translation="MHTFDFLAEHGALVLFWVIFVEQIGFPLPALPLLVAAGALVATE
                     NMSLAAALLVPVAASLPPDLAWYYLGRQKGGKVLGFLCRLSLEPDSCVRDTENVFHRN
                     GPRALLLAKFVPGFSTVAPPLAGIVGMPATTFILYDLGGTLIWAAVSAGVGALFSNQL
                     EQLIGLFDQAGGLMLVILLLGLAGFVGYKFYHRQKFLRHLRMAKISVDELKRRLDAGE
                     SISVVDVRHPLALDLDPESIPGAINFTLEDIEHRHHEIPRDRDIVLYCSCPNEVSSAR
                     TAFLLKKKGIHRVRPLEGGLDAWRERQFPVERRVNIELTQ"
     gene            complement(1894..3519)
                     /locus_tag="PK063_09460"
     CDS             complement(1894..3519)
                     /locus_tag="PK063_09460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97320.1"
                     /translation="MMIAVSRWIDRNILELARDFQLSYLPPLMVYMAAGISGLTGIVG
                     TFFVKDYLGLSAAFLAALGFWAGIPWALKMPFGHLVDLLWRWKSLLVYFGAGVIAASL
                     LIMVGLIGHREAMAAVMPAEVWYVLSALLAPIGYVIQDTVADAMTVEAVPRVDEAGLP
                     IDEAKLKLMHTTMQTLGRVAIISGGILVALINLYLFTGVENLPKDKVAEIYQQVYLLA
                     LTIPAVSVLGVITASVLRLRAKRRFLSQGMTSAQVATLLDRPEEPTKPNWWILGGSLL
                     FVLFTLTVGMADFPFSEEIVFVGSMAIVSVLMVRLTRELAPDARHVLVGTALVVFVFR
                     AVPGPGEGATWWMIDKLGFDQHFLSVLSLIGSALTLAGMFLFRRFMAERSIAYVVGFL
                     TVAAFVLGLPIVSMYYGLHEWTAALTGGVVDARFIALVNTALESPLGQISMIPMLAWI
                     ANSAPANLKATYFAVMASFTNLALSLSQLGTKYLNELFVVTREVRDPVTNAIQTPDDY
                     SQLGILLIVQTVLGLALPFAAILFSRFSRFRSA"
     gene            complement(3659..4732)
                     /locus_tag="PK063_09465"
     CDS             complement(3659..4732)
                     /locus_tag="PK063_09465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c peroxidase"
                     /protein_id="HMZ97321.1"
                     /translation="MDKRRVRWVAGVAAGIMVGVMGMAATRVMGESSAPPPGSAAITQ
                     EVPLGLEDPAAYIPADNPPTAKKIELGRLLFFDKRLSRTNTVACANCHMPGLAFTDGQ
                     AVSMGINRLQGGRSAPTAINRVYSKAQFWDGRAQTLEEQSTGPFINPVEHGFLDYDEM
                     TTKMKKLSGYRQLFQEVFHDDITEKNIGKAIASFQRTLISGNSPADRFDSGGDEQALS
                     ASAKRGLELFRGKARCTRCHSGFNFTDEKFHNLGIGWDTNTVDLGRYMVTKNPDDIGA
                     FKTPTLREIAHTAPYMHDGRFATLEEVVRFYNQGGIQNPHQDNTIIPLELTETEEQEV
                     VAFLRSLNGEGWQQVRAPIEFPK"
     gene            complement(4776..4982)
                     /locus_tag="PK063_09470"
     CDS             complement(4776..4982)
                     /locus_tag="PK063_09470"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97322.1"
                     /translation="MRQIVALMGLGFFVVLLQGCAAPSARGSHDTVAFSEEGGTAATD
                     EEFVKKVERHLDRQDRPGTTLMFR"
     gene            5062..6018
                     /locus_tag="PK063_09475"
     CDS             5062..6018
                     /locus_tag="PK063_09475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogen peroxide-inducible genes activator"
                     /protein_id="HMZ97323.1"
                     /translation="MDDRLAELIAEGFPMTLTELQYIVALAQERHFGRAAERSFVTQP
                     ALSLAIKKLEEELGVTIFERRKHQAVLTPLGEQIVHQAQLVLEEVDQIKLLAAQGKNQ
                     LVGALRLGAIATVGPYLLPDLVPLLHKRAPEMPLEIEENLTVNLTAMLKSGKLDVIMI
                     ALPFEEPGILVQALYDEPFKAVVPADHRLAKKAHLDPSAMTGERVLLPHAGHCFRHQV
                     LEACPELSRSDAEGLQGNSLETIRQMVASGLGITVMPCSAVTSRHLNKRLTVLEFAKP
                     VPERRIALAWRKGFARPAVIAVIHEAVGMLKIPGLESISAQA"
     gene            6042..6395
                     /gene="uraH"
                     /locus_tag="PK063_09480"
     CDS             6042..6395
                     /gene="uraH"
                     /locus_tag="PK063_09480"
                     /EC_number="3.5.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019628 - urate catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyisourate hydrolase"
                     /protein_id="HMZ97324.1"
                     /translation="MEDAHRISIHVLDQSQGRPAEGIPVTLEIRGLTGLWKQLGQGRT
                     DADGRSSDLYPAGLRMQTGTYRLTFDVAGYFRKRNVATFFPEVPIVFTVQDVAQSYHI
                     PLLLSPFGYSTYRGS"
     gene            complement(6414..7091)
                     /locus_tag="PK063_09485"
     CDS             complement(6414..7091)
                     /locus_tag="PK063_09485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ankyrin repeat domain-containing protein"
                     /protein_id="HMZ97325.1"
                     /translation="MKVMLASMCAGLVMVVLGMAVTASPAPDKDQLLIAAAERNDVES
                     VKRLLRDGAGVQARDAQGRTGLMAATYHNHVDVARVLIEAGSDVNAQDAMHNSPLLLA
                     GASGYLDIVRMTLAARPDFTVYNRFGGTALIPACERGHVEVVKALLKTTIDVNHVNRL
                     GWTALLEAILLSDGGTAHQEIVRLLLAAGANPNLADHDGVTPLRHARQKGYRVISDLL
                     LAAGAHE"
     gene            complement(7088..7966)
                     /locus_tag="PK063_09490"
     CDS             complement(7088..7966)
                     /locus_tag="PK063_09490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HMZ97326.1"
                     /translation="MADPHKRLDANIPGNFYVDDTCINCDACRQLAPASFEEVGDYSA
                     VRHQPASAQEIREAYRALLACPTGSIGTEQGDKGVMQAAKADFPLLVEDHVYYCGFNS
                     EKSFGANSFFIRHPEGNWLIDSPRYLKPLVEAFDQMGGIAHIFLTHEDDVADAARYAQ
                     RFGGRRIIHRADAHVMPEAEEIVEGLDAMFYRPEFLIIPVPGHTAGSLCLLYRDRFLF
                     TGDHLWWDPETNELGSPQQLVWDADALRRSIATLTSYPFEWVLAGHGGRIHLPHAHMQ
                     MALRALVRRREGTRLS"
     gene            complement(7950..8633)
                     /locus_tag="PK063_09495"
     CDS             complement(7950..8633)
                     /locus_tag="PK063_09495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HMZ97327.1"
                     /translation="MSEPSAEIAHLSKIDPVMRRVIDAVGPYALPPPPRRSPFEALVR
                     AIAYQQLHEKAAECILTRFIALCPGRRFPQPADVLALAPESMREAGFSRAKIAALQDL
                     AAKAIDGTLPTAAVIRRLDDDAIVDRLVAVRGIGRWTVEMLLIFQLGRPDVLPVDDFG
                     VRNGFRIAYKRPMPTPQELLRYGERWRPYRTAAAWYLWRAVDQAKALQAVTALSKPST
                     RRVSNGRSA"
     gene            complement(8641..9024)
                     /locus_tag="PK063_09500"
     CDS             complement(8641..9024)
                     /locus_tag="PK063_09500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HMZ97328.1"
                     /translation="MGRQNVSTGGPWEGKIGYSRAVRVGQSVQVSGTTAMTGAGLVGK
                     NDPYAQTIQALKTIEAALVQAGASISDVVRTRIYMANIDQWQEVGRAHGEVFGSVRPA
                     TTMVEVKRLIDPDMLVEIEADAIIG"
     gene            complement(9202..9933)
                     /locus_tag="PK063_09505"
     CDS             complement(9202..9933)
                     /locus_tag="PK063_09505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HMZ97329.1"
                     /translation="MRPLTGKVAIVTGSSSGIGRAIAERLARDGATVVVHYHVHAEKA
                     NQVAEGIQSSGGSALVRQADMSRVADAQRLVRETAKELGRLDILVNNAGRFLPRPLLE
                     TTEEEFDAILALNAKGPYFAMQAAARVLSDGGRIVNISSALTHLKFPGATAHLGSKAA
                     LEQYGKGLAQELASRGITVNTVLPGFTDTGVLTEPYRQMGAQMSPTQRLGHPSDIADV
                     VAFLVSEQARWLTGQVIHAGGGLVM"
     gene            complement(10209..10814)
                     /locus_tag="PK063_09510"
     CDS             complement(10209..10814)
                     /locus_tag="PK063_09510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HMZ97330.1"
                     /translation="MEKPAETQYPIHDVLRQRWSPRAYSERMVEPEKLRSLFEAARWA
                     PSSNNEQPWHFIVGTKADPAAYDRLFACLKEGNKKWAFRAPVLMLSVARLNFEDEGTP
                     NRHALHDTGMAALSLCLQATAMGLIAHQMAGFDMEKARTDLGLPAGHEPVAMIAVGYP
                     GDAAELPDYLREREFKPRERKLSTEFVSHGTWNDQPGWLKP"
     gene            complement(10923..11015)
                     /locus_tag="PK063_09515"
                     /pseudo
     CDS             complement(10923..11015)
                     /locus_tag="PK063_09515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002075262.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
     gene            complement(11250..11390)
                     /locus_tag="PK063_09520"
                     /pseudo
     CDS             complement(11250..11390)
                     /locus_tag="PK063_09520"
                     /inference="COORDINATES: protein motif:HMM:NF023880.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="maltose acetyltransferase domain-containing
                     protein"
     gene            complement(11435..12133)
                     /locus_tag="PK063_09525"
     CDS             complement(11435..12133)
                     /locus_tag="PK063_09525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HMZ97331.1"
                     /translation="MAMVHEHDGLAFLFDLDGTLVDSVYQHVLAWREATQAAGIELPV
                     WRIHRQIGMSGGLMLHALLRETGRPVSKEEAERIQRVHAEAFVRQAPSLRILPGAQAL
                     LDALTAGRVPYAIATSGRLQSAQHTLKLLKLPEGTPVVTRDQVKRAKPDPDLFLAAAE
                     QLKVPIAKCIVVGDSVWDLLAARRASALGVGLLSGGYGREELERAGAYRTYHDPADLL
                     RHLDECGVRPDPLM"
     gene            complement(12139..12564)
                     /locus_tag="PK063_09530"
     CDS             complement(12139..12564)
                     /locus_tag="PK063_09530"
                     /EC_number="1.11.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA];
                     GO_process: GO:0006972 - hyperosmotic response [Evidence
                     IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0033194 - response to hydroperoxide
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HMZ97332.1"
                     /translation="MKRNASAKWQGDLKTGKGTVSTESGVLAGTQYSFSTRFENGKGT
                     NPEELIAAAHAGCFTMALSGQLGAANLVADQLATTATVTMEKLEAGWTVTGIHLDVKG
                     KVPKADNAAWEKATTAAKTGCPISRLLNTTITMDAKLES"
     gene            complement(12579..13589)
                     /locus_tag="PK063_09535"
     CDS             complement(12579..13589)
                     /locus_tag="PK063_09535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014448701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HMZ97333.1"
                     /translation="MKAVQATAPGAAWELVERDIPRPKPDQVRVKVQACGICHSDMFV
                     KEGHWPGLQFPRIPGHEIAGLVDEVGSAVTAWKPGQRVGVGWHGGHCGQCDACRRGDF
                     ILCRSGQVCGISYDGGWAEYVVVPEQAMAALPDELSFEEAAPLLCAGITTFNSLRHSG
                     ARAGDLVAVQGIGGLGHLGIQYASKLGLKTVAVGRGKDKEPLARQLGAAVYLDAAVVN
                     PAEELQRLGGARVVLATAPDSKAIASMVDGLGANGTLLIVAAPGEPVMVNAITLIGKR
                     ASVQGWPSGTAKDSEDTLRFSAMTGVRPMIERYPLARAPEAYQQMMSGKARFRAVLTM
                     NS"
     gene            complement(13732..14103)
                     /locus_tag="PK063_09540"
     CDS             complement(13732..14103)
                     /locus_tag="PK063_09540"
                     /inference="COORDINATES: protein motif:HMM:NF012790.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HMZ97334.1"
                     /translation="MATPVMAHDSAKAKEFFEAKMAFTTGPVELERMMKNKEVNVVDV
                     RAAEDYAEGHIPGAVSLPKDQWAGLKGLRKDKVNVLYCYSQVCHLAATAAVQFAGQGY
                     PIMELEGGWRWWKDDGFDVEK"
     gene            complement(14264..15418)
                     /locus_tag="PK063_09545"
     CDS             complement(14264..15418)
                     /locus_tag="PK063_09545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HMZ97335.1"
                     /translation="MTAGQRAARWTQRLAALTWKELLQLSRDVPLLLFLIYSFSLSVL
                     VSGVGITMQLTNAELLVHDEDQSPSSRELIHRFQPPYFAVVGTINNPRQGLQQLDQGQ
                     AMVVLDVPPRFHEALVSGERTAVQLLVDTTNAPQGLSAAAYTVRIAVPFGTETALASA
                     GLSGTKMSMPLVSSAHRVWFNPTQDERWFQSISHLLRMITLFAVLLPAAALVREKERG
                     TVEQLLVSPLSPFQIMFSKVLAMAGVILLATALALYGVLHPVFHVPMKGSALLFFLLT
                     ALHVFTTAGFGLMAATLAKNQAQVAMMALFLVGPMLLLSGITSPFESMPRWVQAIMTL
                     SPLRYYIDITYGVMLKGAGLDLLWKPVGAMLLLGGALFGSGMWRFRRQFQ"
     gene            complement(15429..16559)
                     /locus_tag="PK063_09550"
     CDS             complement(15429..16559)
                     /locus_tag="PK063_09550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HMZ97336.1"
                     /translation="MALKEWKETTRDRLFLLLAFLLPALWLVVFGYGLNLDVEDIPFA
                     VLDRDQSEFSREYLQRFIQSRYFSFRGYAHDEHSLDRLLTETKIRAAIIVPERFQEQL
                     VAGEAVAVQTLLDGTFPLHTDIAKGYVIAINQAFTEDRLIDFLRRSRGLTREQAGVLV
                     RPLSVEVRYLYNEEVRSTWSMVPALVMFTLMLASPLLTALGVVREKETGSIYNIYSST
                     VSRAEFLTGKLLPYILISLVNVCVLWLMAVGLFQVPFKGHFLLFFFASVLFVCCTTGI
                     GLLISLLVQTQMAALIITMVVAMIPTILFSGLLVPVASLTRGAKVQAHLFPAMYFTNI
                     VRGSFLKGVGVEVLWQDLLALALFAGGLGGLTYHLFTKRPKA"
     gene            complement(16580..18559)
                     /locus_tag="PK063_09555"
     CDS             complement(16580..18559)
                     /locus_tag="PK063_09555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HMZ97337.1"
                     /translation="MMGPPASSADEVVRVSGFVKRYKQHRAVNGLDFTVHRGEIYGLI
                     GPDGAGKSSVMKAIAGVLGYEEGSVDVFGTLLDSERAAEQVKRRIGFLPQGLGLNLYP
                     ELSVEENIDFFAKLRLVPETDLQARKARLLSITRLDRFRSRLMKQLSGGMKQKLGLIC
                     TLIHEPELAILDEPTTGVDPVSRRDFWAILAEWQAVKGMTALVSTAYMDEAVRFHRLS
                     FLSHGRVLASGTPADVQSLVPGVVVTFESTPQLEAVERLKHRYAQVESLGPSLHVFSP
                     EQDAEAAVAGIRQVLDPLPVAHLRTDEPELEDVVVALLLKEQDGQTRASERSSQSAPP
                     ANRPQFDGPAVEAKELIRDFGSFRAVDRVSFDMQQGEIFGLLGANGAGKTTVIKMLTG
                     IVPPSGGEGRVAGADMRTASGAIKERIGYMSQAFSLYLDLTVIENIRLFADIYGLARR
                     QAQQRMAWIVEMAGLSGYEHDRTGRLPMGVRQRLALGCALVHSPRVLFLDEPTSGVDP
                     IGRRRFWDLLTRLAREEGVAILITTHYLSEAEHCDRLALMYAGHIVAEGTPADLKTQV
                     EHEVGQLLEIAVDKPGAALAQVTAAGFTGAALFGTKIHVLSRDPSRDEARLREVLGRA
                     DTTVAAVRPRMLSLEDVFVSRVMALEQAAQKKGAS"
     gene            complement(18556..19659)
                     /locus_tag="PK063_09560"
     CDS             complement(18556..19659)
                     /locus_tag="PK063_09560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HMZ97338.1"
                     /translation="MTIRTSMTAAAVLAVVVIAGYVLLDRLVWHNRLPDGLIQANGRI
                     EGDHVTVASKFPGRVVELAAREGAEVLKGSILIRLDDAQTKAKVDQAARLVDSLMAQV
                     EAAHTALAVLNLEVPLSIEAAAAKVESARAVIRKARAVEYEARRDAERIRALLPQQAV
                     SEQQVDQADARWKIAVTEIAVAQAAHDQAGKELAQAELGRERIRSKEAEVAALERQRD
                     QADATLAEARSVLDDLTIVAPTSGTVTTRMVDVGEVVATGAPLLELVDLDRLYLQVYV
                     PELQIGKVRLDLPARIHTDAFPDQPFDATVRYIASKAEFTPKEVQTPDERVKLIYAVR
                     LYLTTNPDHRLTPGLPADAVIRWKDDVAWSKPR"
     gene            complement(19801..20241)
                     /locus_tag="PK063_09565"
     CDS             complement(19801..20241)
                     /locus_tag="PK063_09565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Spy/CpxP family protein refolding chaperone"
                     /protein_id="HMZ97339.1"
                     /translation="MKMQQTVRVAIGVLVLAGALVGAGCHRHHTPAERADWMTNKIAK
                     HLDLDDQQKAKLMAVRDEMVAARAESQAEHKAIMEAAIAQVQSDRLDQAQLIQLMDRH
                     QAEQKRVMQRVLPKLTEWHATLRPEQKAEAVEHIRKWMDRYGDH"
     gene            complement(20299..20595)
                     /locus_tag="PK063_09570"
     CDS             complement(20299..20595)
                     /locus_tag="PK063_09570"
                     /inference="COORDINATES: protein motif:HMM:NF015925.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HMZ97340.1"
                     /translation="MPVTLINVFSVPAATETEFVQWWQDVKAHITTQAGFISGTFHKS
                     LKPDSRFNYINVAIWENETLYWKAYEKSVTPMKEKLGALGVDMTPALYHVAFEY"
     gene            complement(20716..21633)
                     /locus_tag="PK063_09575"
     CDS             complement(20716..21633)
                     /locus_tag="PK063_09575"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97341.1"
                     /translation="MTRTMIVLGSLVLSVALGASSGFTAEGGGKSATHMKVSGVVSKV
                     QSGITTVKTPWGTMKIASTLTPKNLEVGEDVEMQVNENNAVIDVHRKGDKAHSHRFVT
                     GNLAYTAPDRREIKVWTPEGEKAIDVQTGRSKLSALEEGAPVTVELNEAGKMIDINRF
                     TVEMSFDEHPRTKPGYVIQVNGTVTKIQSGLVYVKTPAGQYTISANTAPADAAVGDDV
                     SLWINEEGMVIDHHGKDKHKAGSHRLIFGKLIYAGTTKNVIKLATPEGVKEFPLERME
                     VKTKPIAEGSHIVVELNEEGTVIDLRKAQ"
     gene            complement(21647..21931)
                     /locus_tag="PK063_09580"
     CDS             complement(21647..21931)
                     /locus_tag="PK063_09580"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97342.1"
                     /translation="MLKITLSNTSPGTTFVLSGRLAGPWVDELRTCWVKQEIDQPAPC
                     HIDLREVTFIDEAGTTLLSQMQRAGVTIEASGCLTRAIVQRLDKVVLSQE"
     gene            complement(21996..22502)
                     /locus_tag="PK063_09585"
     CDS             complement(21996..22502)
                     /locus_tag="PK063_09585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HMZ97343.1"
                     /translation="MYSFFKTDDSWAGLILRVVLGGVIFAHGAQKLLGWYGGFGFEGT
                     MGFFTQKMGFPWLVAFLVIIGESIGSLGLIAGLLTRFTAASFVVIMLGAIVTVHLPQG
                     FFMNWFGQQTGEGFEYHLLVIGMSLALLIIGGGKWSLDGLIARWFGERAALPVRKPRE
                     ASFALRMF"
     gene            complement(22524..22655)
                     /locus_tag="PK063_09590"
     CDS             complement(22524..22655)
                     /locus_tag="PK063_09590"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97344.1"
                     /translation="MKDITLWVGWYGMLLTLPLFVAGLLLKDRTETAVLQWVRSHRR"
     gene            complement(22855..24921)
                     /locus_tag="PK063_09595"
     CDS             complement(22855..24921)
                     /locus_tag="PK063_09595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HMZ97345.1"
                     /translation="MSDRDSSGIERYRALLRVAEAIASHSDLSALVQDLARLLPLVVP
                     VNFVGLSLYDSQRGVMRLQVLRANVPAEIIGGHESDPQDTPAGLVWETQQPLLLNDLP
                     TERRWPKVIELMCEDGVRSCCLVPLTSPTQRLGSLEFSSLEQSAYSTSDVELMQQVGR
                     QVAVAVENVLNREAAAASQRDVERQRDRFSLLLRMTNSMASTLDLRQVFKAVSLCLRE
                     LVPQEYASLILCDGQTQRVRLHALDFPDNEGALTEGALSDVAGSLAGLAFERRRPAVA
                     NTLADLKAFSHAVPQLLVRKGFRSMCSLPLLSRDRVIGCLNLASHHEQAFGEQDLEFL
                     SQVAGQIALAVDNAVAYQEIHTLKDRLTEEKLYLEEEIRVEHGFDDIIGDSRPLKQIL
                     GQVEIVAPTDATVLILGETGTGKELIARAIHRLSGRHARTFVKLNCAAIPTGLLESEL
                     FGHERGAFTGAIAQKVGRFELAHGGTIFLDEVGEIPLELQSKLLRVLQEQEFERLGST
                     RTIRVDIRLVAATNRDLAKLVEEGRFRGDLYYRLNVFPLNLPALRDRREDIPMLVRYF
                     AQHYAARMKKTIESIPAPTLEALSRYHWPGNIRELENLVERAVILTPGTQLQVPLQEL
                     KIEARQAPAPGATLQDAERDQILRTLRDTRWVIGGPDGAAARLGLKRTTLTSKIKKLG
                     LSRPRE"
     gene            complement(24983..25723)
                     /locus_tag="PK063_09600"
     CDS             complement(24983..25723)
                     /locus_tag="PK063_09600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HMZ97346.1"
                     /translation="MSDAMDDSGFPVKLIERRLIAEGTMAFHFAKPSQFVFTPGQFVD
                     LTLLQPSETDAAGNSRAFSIASAPHEDTIMVATRLRDTAFKRELQRMPIGSTVRMEGP
                     FGKLVLHSDQTRPAVLVAGGIGITPFRSMVVHAAQQQSPQRLVLFYSNRRPEDAAFLD
                     ELQSLQDKNRHYSFVGTMTEPEKSLHAWRGETGYLNAGLLSKYLAEIDKPMYYVVGPP
                     GMVTALRTILKDAHVEDTDIRIEKFAGY"
     gene            complement(25767..26003)
                     /locus_tag="PK063_09605"
     CDS             complement(25767..26003)
                     /locus_tag="PK063_09605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDGSH iron-sulfur domain-containing protein"
                     /protein_id="HMZ97347.1"
                     /translation="MEEPVIAAKQPAVLELEAGTYYWCRCGRSKKQPFCDGSHKGTSF
                     TPMEFKTVEKKTLALCQCKHTKNPPFCDGSHKSL"
     assembly_gap    26250..26349
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<26350..26749)
                     /locus_tag="PK063_09610"
     CDS             complement(<26350..26749)
                     /locus_tag="PK063_09610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HMZ97348.1"
                     /translation="MKAHYLGHVVFYVKDLQRALAFYRDLLGFHEVGRIFNGAAAALT
                     SGRTHHELLLIQVGDAPGPPPGRRRGLYHIGIKVGDSLDELRTAKRELEQAGIAIDGM
                     SDHTVSQSLYLRDPDGNEVELYVDADEAIWK"
     gene            complement(26779..27171)
                     /locus_tag="PK063_09615"
     CDS             complement(26779..27171)
                     /locus_tag="PK063_09615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97349.1"
                     /translation="MSGQDHTTAHLDNVSRALLRLHKALLDAERVSYERVHGRIPTNG
                     AFFQLVLGDAWFAWLRPLSQLMARLDELSEEKEASDQGEITAVIGSVRTLLTPSEEGN
                     GFGRNYYDALQREPDVVLAHAAVRALLR"
     gene            complement(27201..>27963)
                     /locus_tag="PK063_09620"
     CDS             complement(27201..>27963)
                     /locus_tag="PK063_09620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HMZ97350.1"
                     /translation="VPHPLARPIVRAEGPIRVLGIATTAMTTDEPRYSASDALLEAAL
                     EHAREHLQLDTQLIRLRDLSFRPCEGFYSKAAEACTWPCSITQMDAADQMDRVYEGIV
                     HWADVILVSTPIRWGGASSLYYKMVERLNCIQNQETIANRHLLKDKVAAFIIMGGQDN
                     VQGVAGQLMTFFAEVGCQFPQFPFIDHSRGWSAEDMERNNREVQGSRELREGAEALVT
                     RAADLARLMLEARLISAPLARGGRKAHQLDSEPTG"
     assembly_gap    27964..28063
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<28064..28265)
                     /locus_tag="PK063_09625"
     CDS             complement(<28064..28265)
                     /locus_tag="PK063_09625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rieske (2Fe-2S) protein"
                     /protein_id="HMZ97351.1"
                     /translation="MPDVRWTEIGLVEELKGKPLQEVVCGNTKLALSYRDGTFAAISG
                     ICNHIGGPLGEGRLEGDYVVCPW"
     gene            complement(28303..28761)
                     /locus_tag="PK063_09630"
     CDS             complement(28303..28761)
                     /locus_tag="PK063_09630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5069 domain-containing protein"
                     /protein_id="HMZ97352.1"
                     /translation="MKNLEQVRTLAKDLTKTYPRSPREMLGGYVIGARCADKCRAFLL
                     GINGEYNYWPCSLAALLFTFTGISPDQFKEVVATGATDEELGDWLKEHSKVQDRQAII
                     EWNNTMRDLRLSEMAPAVQAYMEDYIPKYVPSHRPVYTYFDVYDLEEQRL"
     gene            complement(28758..29204)
                     /locus_tag="PK063_09635"
     CDS             complement(28758..29204)
                     /locus_tag="PK063_09635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HMZ97353.1"
                     /translation="MSVQVYGCNHIVIEVTDAKKAVKFYSDVFGLEMLRGGEGAAWCK
                     LGEHQFLAIFEVKTLQPDRMKHFGLMVRDADQIKEVRRKLTKKYKLKMEPHFRCDFRD
                     PWGNRIQVGDLSDESLVWLLPYQEVQKAGITFAKPSRAGSGKGATT"
     gene            complement(29217..29858)
                     /locus_tag="PK063_09640"
     CDS             complement(29217..29858)
                     /locus_tag="PK063_09640"
                     /inference="COORDINATES: protein motif:HMM:NF024853.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family oxidoreductase"
                     /protein_id="HMZ97354.1"
                     /translation="MTAPVLTIEVYSDVVCPWCYVGKRRLEQALESTGRQDSALVFWR
                     PFQLNPTMPKAGMDRRVYLEAKFGGPEEMQAIQNRIAGAGVSAGIEFAFDRIARTPNT
                     FEAHRLIWFAQQQGRQDAAMEELFHGYFTDGLNIGADEVLVSLAARAGLDGAAVGRFL
                     QSQDGVEAVRQEEARGRQLGIRGVPYFLLNGKTVVSGAQPAETFLQAIEHTTR"
     gene            complement(29855..30739)
                     /locus_tag="PK063_09645"
     CDS             complement(29855..30739)
                     /locus_tag="PK063_09645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pirin family protein"
                     /protein_id="HMZ97355.1"
                     /translation="MRTETMNAKELVGVYQAGSHHMVGDGFPVRNMIPGAGVEEQLSP
                     FLMLDYMGPEEFPPTTRRLGVGEHPHRGFETVTIMYHGKVAHRDSTGSGGVIGPGDVQ
                     WMTAASGVVHEELHEKEFAEKGGLLEGVQLWVNLPKAFKMTAPRYQTLLSSDIPMVEL
                     GGGAGRLRVIAGEFRGVAGPAKTFSPVHLYDLRLAAGHRLELDLPEGFNSSLFVLHGQ
                     VVVNGSQSVDDVHIALFGQRGERVVLEAKQEATILVLSGKPIAEPIARYGPFVMNTRD
                     EIIQAVQDYQAGKMGHLS"
     gene            complement(30754..31611)
                     /locus_tag="PK063_09650"
     CDS             complement(30754..31611)
                     /locus_tag="PK063_09650"
                     /inference="COORDINATES: protein motif:HMM:NF017206.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HMZ97356.1"
                     /translation="MLVVLGATGHTGSVVAQTLLTHKQPVRVVVRSADHGATWAAKGA
                     EVAVASLDDQAALTKALQGASGVYLLVPPNYGATSWLAEQRRRVDQTAEAVKATRIAH
                     VVLLSSIGAHLPEGTGPIRAARYGEHRLTAVAPNVTILRPGYFMENWANGIGMAKAEG
                     LLPSFIPPKMSMPMISTRDIGRVAAERLIAGGEGHAIVELAGPEEYSPEEVASELGRI
                     FGRGVSVQAAPLSAVVPTFTSFGFSTEAAGLFQEMYTAFSKDVVRYERPQSLVRGTKA
                     LAEALREMA"
     gene            complement(31970..32449)
                     /gene="smpB"
                     /locus_tag="PK063_09655"
     CDS             complement(31970..32449)
                     /gene="smpB"
                     /locus_tag="PK063_09655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HMZ97357.1"
                     /translation="MTKTHDTDDQYKVVATNRKAYHDYFVEEKFEAGVILRGTEVKSL
                     REGRVNLQDSYASVDDGEVYLNHCHISPYSHGNLMNHDPLRKRKLLLHRKEINKLIGK
                     TQLKGLTLVPLRIYFSKRGHAKVELALAKGKKQYDRRESIKAREAGREVERAIKSRK"
     gene            32502..32999
                     /locus_tag="PK063_09660"
     CDS             32502..32999
                     /locus_tag="PK063_09660"
                     /inference="COORDINATES: protein motif:HMM:NF017103.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF721 domain-containing protein"
                     /protein_id="HMZ97358.1"
                     /translation="MRGQSRLDSFGTILAGVAHRLGLESKLFEARLRRHWPEIVGEPI
                     ATHTRPDQIRFKKLHVYVHNSVWLQQLTFLKPVLLEKVNGMAGETLVTEIVLRIGEFS
                     AERKVSPPAATVEEPVPQPSAELLQETALHTQNIQDPALREQLAAVMAQALSGIPPDS
                     SRRAP"
     gene            complement(32944..33558)
                     /locus_tag="PK063_09665"
     CDS             complement(32944..33558)
                     /locus_tag="PK063_09665"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97359.1"
                     /translation="MVMNQQQPPSAGTSAGRPPKRPLDTVVKLALGVLFSSFALIWGG
                     MFLSRPDRSIPPYSIGSQEGSIVAVHVPSWTSDTEIQTLIERFRKVGTETRNFGPMKI
                     RPTTADDPKGRYQRIAIYIFTDEGWTEPEMLHKYVTGEDPAVRDGFEGSARGYYKLDE
                     QEEEGRIGPVPKGKDSAATAAYSRQLFKGPVATSPAVSPTTPAP"
     gene            complement(33598..>35249)
                     /locus_tag="PK063_09670"
     CDS             complement(33598..>35249)
                     /locus_tag="PK063_09670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="DNA gyrase C-terminal beta-propeller
                     domain-containing protein"
                     /protein_id="HMZ97360.1"
                     /translation="KLIEKIADLAQEDRVTGISDIRDESDREGVRVVIELKRNEIPLV
                     VLNNLYKHSQLQTTFGVNMLALVNNRPEVLNLKRILEAFVEHRREVVVRRTAYDLRKA
                     EERAHILEGLKIALDNLDAVIALIRRSQSPDVARAGLMQQFRLSEIQANAILEMRLQR
                     LTQLERDKLVEEYREVLKTIEYLRSVLGSEALVRKIIRDELTEIKEKYQDERRTKIVK
                     EEAELTLEDLIAEEEVVVTISHAGYIKRNAVTLYRAQRRGGKGKIAMGIKEEDFVETL
                     FTASTHDSLLFFTDAGKVYWLKVHEIPEASRAAKGKALVNLLALSKDEKVTATLPVKE
                     YRADRFVIMGTKQGVIKKTELSAYSNPRQGGIIALSLDAGDKLIGVDLTDGQREILLG
                     TKQGITIRFKEEDVRAMGRTAHGVRGITLEAGDEVIGMETITPDSTTAILTVTEGGYG
                     KRTPVNEYRVQGRGGKGIISVKTTERNGAAVGFLQVRDEDEIMLMAAQGKVLRCKVDD
                     IREIGRNTQGVRLLDMDGDEDRVVAVVRLVEREEGVPEEGE"
BASE COUNT         7140 a        11170 c         9639 g         7100 t
ORIGIN      
        1 agatctcgac atgcgacgat ggcgtcaata tccccgtcga aaccggtcgc cccctttcag
       61 tcgaatgttg aaaaagattt ctggcggcgt tctcactcgc tcaggttctc gacgtacggg
      121 acatgcacgc ctcgaacctt cgcatcgcta cgggcttgcc agaagatctt tgaccagcca
      181 tttactcttt tgagataccc atcttatcgc atggatcaag gggaagccag agaagaagca
      241 gaggtgtgcg atcactcact gatcggcaca ttacggtagc ggcgtgaagg tccaggtcca
      301 accctgatcc tgctgcttca acacctgccc cttcggcacc cccccggcca atatttccgg
      361 cggtacggtc acaagcaact gttcctcgcg gacctcccct tgcacgggat gggtgccttt
      421 gcacccgcct ccaccgacat attcctccat gtccggcgtt ctccgctctc cgaccaagcc
      481 aaacatggtc ccgattaccg cgatgctttt gagatcgaag tgttcgtacg tgcttttgag
      541 caccggtgcc tggcacactg ccgaaccatc acggaggtta tccactttcg tcggaatatt
      601 cgggagcacc ttgggttgca ccccttccac cagcggccag gtaaattcaa attccacctg
      661 ctcggtcaca tcggccacgg cagatccccc gataaactgt ttgtctcgct ggaagactcc
      721 cacgaccttg tacgtcacgc ctgcggcttt ctggcgcgag ggactcttca cctcccgaat
      781 cgcgtaggta tcggaacccg tcttccagtc tctccctgcg ctcgtctccg ccccgccgga
      841 gagcaggacg atccctgcga tcactggaag cgccagaccc gtcataggca tcgtcctttc
      901 ctcgcctgaa gattccacag actcactgag tcagctcgat attgacccgc cgctcgacgg
      961 gaaactgacg ctcccgccag gcatccagcc cgccttccag aggcctcacc cggtgaatgc
     1021 ctttcttctt gagcaaaaag gccgttctgg cgctggagac ttcattcggg cagctgcagt
     1081 agagcacgat gtcgcgatcg cgcgggatct cgtgatgccg atgctcgatg tcttccaacg
     1141 taaagttgat agcgccggga atgctttcgg gatccagatc gagggccagc ggatgccgga
     1201 catccaccac gctgatagac tcccccgcat ccagacgccg cttgagctca tcgacggaaa
     1261 ttttcgccat gcgcagatgc cgcaggaatt tctgccggtg ataaaactta tagccgacga
     1321 atcccgccag acccagcaga aggatcacga gcatcagtcc tcccgcctgg tcaaatagtc
     1381 cgatgagctg ttccagctga ttgctgaaca acgcgccgac tccggcgctg accgccgccc
     1441 aaatcagcgt gccgccgaga tcgtacaaga taaacgtcgt ggcgggcatg ccgacaatgc
     1501 cggcgagggg aggcgccacc gtgctgaagc cgggaacaaa tttggccaac agcaatgcgc
     1561 gagggccgtt ccggtgaaac acattttccg tatcccgcac acaggaatcg ggttccagcg
     1621 acagccggca gagaaagccc agcaccttcc cgcccttctg acgacccagg taataccagg
     1681 caagatccgg cggaagagaa gcagcaaccg gcaccagcaa cgccgccgcc agactcatgt
     1741 tttctgtcgc aaccagcgcg cctgcggcca cgaggagtgg aagcgcaggg agcggaaacc
     1801 cgatctgctc gacgaagatc acccagaaga gcaccaaggc cccatgctcg gcgagaaagt
     1861 cgaacgtatg catagcggat gacgtcctcc cgcttaggca ctccggaaac gcgagaaccg
     1921 cgaaaagaga atagccgcaa aggggagcgc gaggcccaac accgtttgca caatcagcaa
     1981 tattcccagc tgactgtaat catcaggcgt ctgaatggcg ttggtgaccg gatcgcgcac
     2041 ttcccgagtc accacaaaaa gctcgttgag atatttcgtc ccgagctggc tgagcgacaa
     2101 cgccagattg gtgaaggagg ccatgacggc gaaatacgtg gccttcaaat tcgccggcgc
     2161 ggagttcgca atccaggcca acatgggaat catggagatc tggccgaggg gcgattcgag
     2221 cgccgtattc accaaggcga taaaccgcgc atccactaca ccgccggtca gcgccgcggt
     2281 ccattcgtgc agcccgtaat acatgctgac gatggggagc ccgaggacaa aggccgccac
     2341 ggtaagaaag ccgacgacat aggcaatgga ccgttcggcc ataaatcgcc gaaagagaaa
     2401 catgccggcc agggtcaagg cactgccgat gagcgataac accgaaagaa aatgttgatc
     2461 gaagcccagc ttgtcgatca tccaccaggt cgcgccttcg ccgggtcccg gcaccgcgcg
     2521 aaagacaaac accaccagag ccgtgcccac gagaacatgc ctggcgtcgg gagccagttc
     2581 gcgagtcagc cgcaccatca agaccgagac gatggccatc gatccgacga agacgatttc
     2641 ttcgctgaac ggaaaatccg ccatgcccac cgtcagggta aacaagacga acagcaggct
     2701 gcctccgaga atccaccaat tgggcttggt tggttcctca ggcctgtcca gcagcgtggc
     2761 aacttgagca gatgtcatgc cctggctgag aaaccggcgc ttggctcgca gccgaagcac
     2821 cgacgcggtg atgactccga gtaccgacac ggccgggata gtcagcgcca ggagatagac
     2881 ctgctgataa atctcagcga ctttgtcttt tggcagattc tcgacacccg tgaacagata
     2941 cagattgatg agggcgacca gaatcccgcc gctgatgatg gccacacggc cgagcgtctg
     3001 catcgtcgtg tgcatgagct tcagcttggc ttcatcaatg ggaagccctg cctcgtcaac
     3061 tctcgggacc gcctccaccg tcatggcatc agcaaccgtg tcttgaatca catagccgat
     3121 aggggcgagc agcgcgctca gcacatacca gacttccgcc ggcattacgg ccgccattgc
     3181 ctcgcgatga ccgatcaagc cgaccatgat cagcagactg gccgcaatga cgcccgcacc
     3241 gaaatagacg aggaggctct tccatcgcca caggagatcg accagatgcc cgaatggcat
     3301 cttcagcgcc caggggatac cggcccagaa tcccagggcg gcgagaaagg cggcggaaag
     3361 gccgagataa tctttcacga agaacgtgcc gacgataccg gtcagcccgg agatgccggc
     3421 cgccatgtag accatgaggg gaggcaaata ggatagttgg aagtcgcggg cgagttccag
     3481 aatattacgg tcgatccagc gggaaacggc gatcatcata tggcggtaac cagaaccggt
     3541 gcaggcccca ttgccctcct ctctgttacc cgtaccggac aggcatttgc aagcagggcg
     3601 gcagtaacac gagagggccc cggtcttcga accgggaccc cctcgccatg acagacgctt
     3661 atttgggaaa ctcgatgggc gctctcacct gctgccagcc ctcgccgttc agcgatcgca
     3721 agaaagccac tacctcctgc tcttccgttt cggtcagttc gagcggaatg atcgtattgt
     3781 cctggtgggg attctggatg ccaccctggt tgtaaaaacg gaccacctcc tccagcgtcg
     3841 cgaaccgccc gtcatgcatg tatggcgcgg tgtgcgcaat ttcacgcaga gtcggcgttt
     3901 tgaatgcgcc aatatcgtct gggtttttag tcaccatata ccggccgaga tccacggtgt
     3961 tggtatccca gccgatgccc agattgtgaa atttctcatc ggtgaagttg aagccggagt
     4021 ggcaacgggt gcaccgtgcc ttgccgcgga acaattcgag gcctcgtttg gcggaagcgc
     4081 tcaaggcctg ctcatctcct ccggaatcga atcgatccgc aggactattg cccgaaatca
     4141 gcgtgcgctg aaaactggca atcgctttgc caatattctt ctccgtaatg tcgtcatgaa
     4201 acacctcttg aaagagctgg cggtagccgc tcagcttttt catcttcgtc gtcatttcat
     4261 cataatccag aaagccgtgt tcgacaggat tgatgaacgg cccggtcgat tgttcctcga
     4321 gggtctgagc gcgcccgtcc caaaactgcg ccttgctgta cacgcgattg atggccgtgg
     4381 gagcacttcg accaccttgc agccgattga tccccatgga cacggcttgt ccgtcggtga
     4441 atgccaagcc cggcatgtgg caattcgcac aggccacggt gttggtcctg gataaacgtt
     4501 tatcgaagaa cagcaagcgc ccaagctcga ttttcttcgc tgtcggcggg ttgtcggcgg
     4561 gaatatatgc tgcgggatcc tctaacccaa gcggtacctc ctgcgtgatg gcagccgagc
     4621 caggtggcgg tgccgacgat tcgcccatga ctcttgtggc cgccatgccc atcacgccca
     4681 ccatgattcc tgccgccact cccgcgaccc atcgcaccct tctcttgtcc atggctcctc
     4741 ccatccttcc ttcgtcggtg ccgatcactc acacattatc gaaacatcaa tgtcgtacca
     4801 ggccggtcct gccgatccag gtgccgttcg accttcttaa cgaattcctc atcggttgcg
     4861 gccgtaccac cctcttccga gaaggccact gtgtcgtgac tgccgcgcgc agacggtgcc
     4921 gcacaaccct gcagcagaac aacgaagaac ccgagtccca tgagcgctac gatctgtcgc
     4981 atgctccacc tccttgttgc ctgcagtcga ctcatgacgc cacgataccg gttgccggat
     5041 gatcagtcca attgatagtg tatggatgat cgattagcag aacttatcgc tgaaggattt
     5101 cctatgaccc tgaccgagct gcagtacatc gtcgcactcg cgcaagaacg gcatttcggc
     5161 cgggcagccg agcggagttt cgtgacgcaa ccggcgctga gtctggcgat caaaaagctg
     5221 gaggaagagt tgggagtgac gatctttgaa cgacgtaagc accaggcggt cctcacgcca
     5281 ctgggtgaac agatcgtcca ccaggctcaa ctggtgctgg aggaagtgga tcagatcaaa
     5341 cttctcgcgg cccaagggaa gaatcagctc gtgggcgcct tgcgtctcgg cgcgatcgcg
     5401 acggtgggcc cctacctcct gccggatctc gtaccgctcc tgcataagcg ggcaccggag
     5461 atgccgttag agatcgagga gaatttgacg gtcaacctga cggccatgct gaagagcggc
     5521 aagctcgacg tcatcatgat cgcgttgccg tttgaagaac cggggattct ggttcaagcc
     5581 ttgtacgacg aacccttcaa ggccgttgtg ccggcggatc atcggctggc aaagaaagcg
     5641 catctcgatc cctctgccat gaccggtgag cgcgtcctgc ttccccatgc cggacactgc
     5701 ttcagacatc aggtgctgga ggcctgtccg gagctcagcc gctcagatgc ggaaggcttg
     5761 cagggcaatt cgctggagac gattcgccag atggtcgcct ccggactggg cattaccgtc
     5821 atgccctgca gcgctgtgac cagcagacat ttgaacaaac ggctcactgt gttggaattc
     5881 gcgaaaccgg tgcccgagcg gcgcattgcc ctggcgtggc gcaagggatt tgccagaccg
     5941 gccgtcatcg cggtgattca tgaagccgtg gggatgttaa agatcccggg gctggaatcg
     6001 atctccgcac aggcctgacg gatcgtgtga aaggagcgtt tatggaggac gcacatcgga
     6061 tcagcatcca tgtgttggat caatcgcaag gacggccggc agaaggaatc ccggtgacgt
     6121 tggagattcg agggctcacc ggtctctgga agcagctcgg ccaaggacga accgatgcgg
     6181 acggccgtag ctcggacctc tatcctgcgg gcctccgcat gcaaaccggc acctatcggc
     6241 tcacattcga cgtggccggc tattttcgga aaagaaacgt ggcgacgttc ttcccggagg
     6301 tgccgatcgt gtttaccgtg caggacgtgg cgcagagcta ccatatccca ctgctactca
     6361 gtcccttcgg ctatagcacc tatcgtggca gttgagcgaa cacgcgagtc cgtctactcg
     6421 tgcgcaccgg cagccagcag cagatctgag atcacgcggt aacccttctg cctggcatgc
     6481 cgcagcggtg tgacaccatc gtgatcggca agattcggat tcgctccggc agcgaggagc
     6541 agacgaacga tctcttgatg cgccgtgccg ccgtcactca ataggatggc ctcaagcagg
     6601 gccgtccagc cgaggcggtt cacgtgattc acatcgatcg tggtcttgag caaggccttg
     6661 accacctcga catggccgcg ctcacaggcc gggatcaacg ccgtaccacc gaaacgattg
     6721 tagaccgtga agtccgggcg cgcggccaat gtcattcgca caatatccag ataaccactg
     6781 gccccggcca gcagcaaggg gctgttgtgc atggcgtcct gcgcattcac gtccgaaccg
     6841 gcttcgatca gcaccctcgc cacgtcgaca tggttgtgat acgtcgcggc catgagtccc
     6901 gtgcgaccct gcgcatcacg agcctgaacc ccggcgccat ctcgcaacaa ccgtttcact
     6961 gattcaacgt cattgcgttc cgccgctgcg atcaagagct ggtccttgtc gggagcaggg
     7021 gaggcggtga cggccatgcc tagcacgacc atgacgagac cggcacacat cgaagcaagc
     7081 atgaccttca tgatagccgc gttccctccc ggcgacggac caatgcgcgt aaggccatct
     7141 gcatgtgcgc gtgaggcaaa tgaatccgtc ctccatgacc ggccagcacc cattcgaatg
     7201 gataggacgt caacgtcgcg atcgatcggc gcaatgcatc ggcgtcccag actaattgct
     7261 gaggggagcc caattcattg gtctccggat cccaccagag atgatcaccc gtgaacaaga
     7321 accggtcccg atataggaga caaaggctgc ccgccgtatg gccggggacc gggatgatca
     7381 gaaattccgg tcgatagaac atcgcatcga gcccctccac gatctcttcc gcttccggca
     7441 tcacatgcgc atccgcccgg tgaatgatgc gtctcccccc gaatcgctgc gcgtacctgg
     7501 cggcatcagc cacatcgtct tcatgggtca gaaagatgtg cgcgattcct cccatctgat
     7561 cgaaggcctc gaccagaggt ttgagatatc gcggcgaatc gatcagccag ttgccctccg
     7621 gatgccggat gaagaagctg ttcgcgccga aggatttttc tgaattgaag ccgcaatagt
     7681 agacgtgatc ttccacgagg agagggaagt cggccttcgc tgcctgcatc acgcccttgt
     7741 cgccctgctc ggttccgatc gatccggtgg ggcaggcgag gagcgctcgg taggcctccc
     7801 tgatttcctg cgcactagcc ggttgatgcc gcacggctga gtagtctccg acttcctcaa
     7861 agctggcagg ggcaagttga cgacaggcat cgcaattgat gcaggtgtca tcgacataaa
     7921 agttgccggg gatattggcg tctaatcgct tatgcggatc ggccattgga gactcgcctg
     7981 gtcgaaggtt tcgacagtgc cgtcacggct tgcagggctt ttgcctgatc gaccgcgcgc
     8041 cacagatacc aggcggcggc agtccgatac ggccgccacc gttctccata tcgtaacagt
     8101 tcttgagggg tcggcatcgg ccgcttgtag gcgatccgga agccgttccg cacgccgaag
     8161 tcatcaaccg gcaggacatc gggacggccc agttgaaaaa tcagcaacat ctcgacggtc
     8221 caccggccga tccctcgcac cgccaccagc ctgtcgacaa tggcgtcgtc atcgagccgt
     8281 cgaatgacag cggcggtagg gagggtgcca tcgatcgcct tcgccgccaa atcctgcagc
     8341 gcggcaatct tcgcgcgcga gaatcccgct tctcgcatgc tctccggggc caaggccaac
     8401 acgtcggccg gctgtggaaa ccggcggccc gggcacaacg cgatgaatcg ggtaagaatg
     8461 cactccgccg ccttctcatg aagttgctgg taggcgatgg ctcggaccag cgcttcaaat
     8521 ggagagcgcc ttggcggagg aggcagcgca taggggccga ccgcgtcgat cacccgcctc
     8581 atcaccggat cgatcttaga cagatgagca atttccgccg agggttcgct catggggcta
     8641 ttacccaatg atggcgtcgg cttcgatttc gacgagcatg tccggatcga tcaagcgctt
     8701 cacctccacc atggtggtcg caggcctgac cgacccaaac acctccccat gtgcgcggcc
     8761 gacttcctgc cattgatcga tattggccat ataaatgcgc gtccgcacga catcagaaat
     8821 cgatgcgccg gcctgcacga gcgccgcttc aatcgtcttc aaggcctgaa tggtctgcgc
     8881 gtagggatca ttcttcccca cgagtcctgc tcccgtcatc gccgtggtgc cggagacctg
     8941 cacggattga ccgacccgca ctgcccgcga atagccgatt ttgccttccc aaggtccccc
     9001 agtcgaaacg ttctgccttc ccatgattcc tcctttgatc gtctgcgaac actccacttt
     9061 acacggcacg caggatgcgc aaaaaggctt tccagcaagg ccccagtgaa tggagagccg
     9121 aagcgtaccc cttacggtac gttgaggttc gccatgaagc gagaacgccg ctggaggctg
     9181 tgttccccat cctgctacac gttacatcac caggccgccg cctgcatgaa tcacctggcc
     9241 ggtcaaccac cgggcctgct cactcactag aaacgccacc acatcggcga tatcagaagg
     9301 atgtccgagc cgctgcgtgg gcgacatctg cgcgcccatc tggcgatacg gctccgtcaa
     9361 gactccggtg tccgtaaaac cgggaagcac ggtgttgacc gtgatccccc gggaggccaa
     9421 ctcctgcgcg agccctttgc cgtactgttc cagggctgct ttgctcccca ggtgcgcggt
     9481 ggcgcccgga aacttcagat gggtgagcgc cgacgaaata ttcacgatgc gtccgccgtc
     9541 gctgagaacc cgcgccgcgg cctgcatggc aaagtatggt cccttcgcat tcaaagcgag
     9601 aatcgcatcg aactcctctt cggtcgtctc cagtagggga cgaggaagaa accggcccgc
     9661 gttgttcacg agaatatcca ggcggcctaa ctccttcgct gtctcccgca ccaatcgctg
     9721 ggcatcggcc acccggctca tgtcggcctg ccgcaccagg gcgctgcctc cactggactg
     9781 aatcccttca gccacctggt tggccttctc ggcatgcaca tggtagtgga ccacaacggt
     9841 cgcgccatcc ctggccaatc gttcggcaat cgcccggcca atgccgctgg aagaccccgt
     9901 gacaatggcg actttgcccg tcaaaggcct cattccggca cctccgcctt aaccatgcgt
     9961 tccattgatg atcccgttcg cgcaatcgtt gtggattaga aagaccgttg cattgagcct
    10021 ggacggtctg cggcagacag cccggcgcct gtacactgta tcaattcagc tgagccgaga
    10081 tccaacggca attcttacgg tgcgcaagat aggaagcacc agcgtgagaa tactatgcgt
    10141 agaggacggg cgaggatcgg accgttgtgt ctcgggtccg ttcaattgat aggaaggaga
    10201 ggcgcctcct atggtttcag ccatccaggc tgatcattcc aggtaccgtg agagacgaat
    10261 tccgtgctga gtttccgttc gcgtggtttg aattctcgtt cgcgtagata gtccggcagc
    10321 tcggccgcat caccaggata tccgacggcg atcatcgcca ccggctcatg ccccgcaggc
    10381 agaccgaggt ccgtacgagc cttctccatg tcgaagcctg ccatctggtg cgcgatcagc
    10441 cccatcgccg tggcctgtaa gcacaagctc agcgccgcca ttcccgtatc atgcaaagcg
    10501 tgccggtttg gcgtgccttc atcctcgaaa ttcagccgcg ccacggagag catcagcacg
    10561 ggcgcccgga acgcccattt tttgttgcct tccttgagac aggcaaacag tcggtcatac
    10621 gccgccgggt cggctttcgt gccgacgatg aaatgccatg gctgttcgtt gttcgaagag
    10681 ggagcccatc tggccgcttc aaacaggctt ctcaacttct ccggttcgac catccgttcc
    10741 gaataggccc gcgggctcca gcgttgccgc agcacatcat gaatgggata ttgcgtctca
    10801 gcgggctttt ccatgaacga tccttccgtg aattattctg ttgtcagggt gggtgagccc
    10861 aatgtgcgca ccacgcgtgc cggattgccg accgcgacac aatcggcggg gaccgagtgc
    10921 acgaccacgc tgcccgcacc caccacgctg cgatcaccaa tcgtcacacc ggggagaatc
    10981 accgccccgc cgccgatcca gacgtcattg ccgatccgga tcggtcgcgc agattccagg
    11041 cccgaccggc gtacctccgc ctcgagcgga tgctgcgccg tgtagagctg cacggcgggg
    11101 ccgacttgca catcattccc gatatcgata ggggcacagt cgagaaaaat gcagtgatag
    11161 ttgatgaaca cgttcaggcc caggcggata ttgtagccgt agtcgcacgt gaactgcggc
    11221 atgatgacgg taccgtctcc gacggaaccc atcaaatcac gaagcagtga cagcaagaga
    11281 tcaggctcac catccgtgat ggcattatag cgagcgagca tcatctgcgc gcggcgacgc
    11341 tccatggtga gctcagcaga ggatgcgcgg tacagctccc ccgccaacat gttgcgtttg
    11401 tcgcgttgtt cagtcatcgc gttcagcacg tcgcttacat gagtgggtca ggccgaaccc
    11461 cgcattcatc caggtgacgc aggagatcgg cggggtcatg gtaggtacgg tacgcacccg
    11521 cccgttccaa ttcctctcga ccatagccgc ccgatagcag gccaactcca agggcagagg
    11581 cacggcgggc tgccaggagg tcccacacac tgtctccgac cacgatacac ttcgcaatgg
    11641 gaaccttgag ctgttcggca gcagcgagaa acaaatcagg atccggtttg gcccgtttca
    11701 cctgatcacg cgtcaccacc ggcgtgcctt caggcaactt cagcaatttc aaggtatgtt
    11761 gcgcgctctg gagccgtccg ctggtcgcga tggcataggg cacacggccc gccgtcagcg
    11821 catccagcag agcctgcgcg ccgggcaaga tgcggagtga tggcgcctgc ctcacgaacg
    11881 cctccgcgtg gactcgctga atgcgctccg cctcctcctt cgaaacggga cgaccggttt
    11941 cgcgcaagag ggcatgcaac atgagaccgc cgctcatgcc gatttggcga tggatcctcc
    12001 agaccggcaa ttcgatacct gcggcttgag tggcttcacg ccaggccagc acatgttgat
    12061 agacactgtc gaccaacgta ccgtccaggt cgaagaggaa cgcgagcccg tcatgctcat
    12121 gcaccatggc catatctgtc agctctccaa cttggcgtcc atggtgatgg tggtattcag
    12181 taagcgggaa atggggcagc cggttttggc cgctgtggtc gccttctccc atgccgcatt
    12241 gtcagccttg ggcactttcc cctttacgtc caggtgaatg ccggtcacgg tccatcctgc
    12301 ctcaagcttc tccatggtga ctgtggcggt cgtcgccagc tggtcggcca cgagattcgc
    12361 cgcgcccaat tgaccggaga gtgccatggt aaaacaaccg gcatgggcgg cagcgatcaa
    12421 ctcctccggg ttcgtccctt tgccgttctc gaacctggta ctgaatgaat attgcgtccc
    12481 ggccaacaca ccgctctcgg tcgagaccgt ccctttgccg gttttgagat ctccctgcca
    12541 ctttgccgac gcattgcgtt tcatgaccac ctccgttgtt aagaattcat cgtcaggacg
    12601 gcgcgaaagc gtgccttgcc gctcatcatc tgctgatagg cttccggtgc gcgcgccagt
    12661 ggataccgtt cgatcatggg ccgcacgccg gtcatcgcgc tgaatcgcag cgtatcttca
    12721 gaatccttcg ccgtgccgga cggccagccc tgcacggagg ctcgtttacc gatcagcgtg
    12781 atggcattca ccattaccgg ttcgcctggc gcggccacga tgagcaaggt tccattcgca
    12841 cccagtccgt cgaccatcga tgcgatcgct ttgctgtccg gcgcggtcgc cagaacgacc
    12901 cgggcgccgc ccagtcgttg aagctcctcg gctggattca ccaccgcggc atcgagatag
    12961 accgccgcac cgagctgacg ggccagcggc tccttgtctt taccgcggcc gaccgccact
    13021 gtcttgagtc ccagcttcga ggcatactga atgccgagat gtcccagccc gccgatgcct
    13081 tgcacggcga ccaggtcacc cgcccgagca ccactgtggc gcaaactatt aaaggtggta
    13141 atgcctgcgc agagcagtgg agcggcctct tcaaacgaga gttcatccgg cagggcagcc
    13201 atcgcttgct ccggcaccac cacatattcc gcccaccctc cgtcgtagct gatcccgcag
    13261 acctgccccg accggcagag aataaaatct ccccggcgac aggcgtcgca ctggccacaa
    13321 tggcccccgt gccagcccac accaacacgt tgaccaggtt tccacgctgt gacagcggat
    13381 cccacctcat cgactaatcc ggcaatttca tgccccggga tacgggggaa ttgcagcccc
    13441 ggccaatgcc cttctttcac aaacatgtca ctgtggcaga taccacaggc ctggaccttc
    13501 acccgcacct gatcaggttt cggtctggga atatctcgtt ccaccagctc ccatgcagct
    13561 cccggagcag tggcttgtac agccttcatg cgcgccatca tgatgccctt tctgaataca
    13621 cgtatgtggc accggcgtgg cgcaacctgt ccttaacgga aagactgccc cacgccctct
    13681 atcttctgcg accacgtcct acccgggagc gtgaatcgat gaacggccgc ttcacttctc
    13741 gacgtcgaag ccgtcgtctt tccaccatcg ccaccctccc tccaattcca tgatcggata
    13801 gccctgcccc gcaaactgca ccgcagcggt ggcggcaaga tggcagactt gcgaataaca
    13861 gtagaggacg ttgaccttgt ccttgcgtag acctttgagg cccgcccact ggtccttggg
    13921 caaactgacc gcgccgggaa tatgcccttc ggcgtaatct tcggccgcgc gcacatcaac
    13981 cacattcact tctttattct tcatcatccg ctccagttcg accggaccgg tggtaaatgc
    14041 cattttcgcc tcgaagaact ccttggcttt ggccgagtcg tgcgccatca ctggtgtcgc
    14101 catggtcatc ctccctctga atcgtgacgt gtgtatgctg ttcgcgtcgg actggcctcc
    14161 caggctcaag cgggacgcca gcctcacggg ttggcttcta ccttgtaacg ttagagagtc
    14221 tggtgcctct atgcaagcgc tgatcgctcg ccttttggat ggctcattgg aattgtcgtc
    14281 gaaaccgcca catcccggaa ccgaacagcg ccccgcccaa caacagcatg gcaccgaccg
    14341 gcttccacaa cagatccaag ccggccccct tcaacatcac gccgtaggtg atgtcgatgt
    14401 agtagcgaag aggggagagg gtcatgatcg cctgcaccca tcgaggcatc gattcaaatg
    14461 gcgaggtaat gcctgacaac aacagcatcg ggcccaccag gaagagcgcc atcatggcca
    14521 cttgcgcctg attcttcgcc agagtcgccg ccatcagccc gaatccggcc gtcgtgaaga
    14581 catgcaaggc ggtcagcaga aaaaagagta gtgccgatcc cttcatcggc acgtgaaaca
    14641 cgggatgcaa cacgccgtac agggccagtg cggtcgcgag gagaatcacc ccggccatgg
    14701 cgagcacttt cgaaaacatg atctgaaacg gggacaatgg ggacaccaat aactgctcga
    14761 ccgtgcctcg ctctttttca cgcaccaacg cggcggccgg caacaacacc gcgaagagcg
    14821 tgatcatccg caacagatgc gaaatggact ggaaccatcg ttcgtcctgg gtcggattga
    14881 accagacacg atgcgcactg gagacaagcg gcatgctcat cttcgttccg gacagacctg
    14941 cagaggccag agccgtctcg gtgccgaacg ggacagcaat gcgcacggta taggcggcgg
    15001 cggaaagtcc ctgtggcgca ttggtagtat cgaccagcag ttgaaccgcc gttcgctccc
    15061 cgctcacgag ggcttcgtgg aatctcggag gaacatccaa caccaccatc gcctggccct
    15121 gatccagttg ctgaagccct tggcgcgggt tgttgatcgt gcccaccaca gcaaaatagg
    15181 ggggctgaaa ccgatgaatc agctctcgtg aagagggact ttgatcctca tcatgcacca
    15241 gcagctccgc attggtgagc tgcatcgtaa tcccgactcc gctgaccagc actgacagag
    15301 aaaatgaata gatcaggaat aataacaacg gtacatcgcg cgacagttgc aggagttcct
    15361 tccacgtcag cgccgcaagt cgttgtgtcc acctggctgc ccgctgcccg gccgtcatgc
    15421 catacccctc atgctttggg tcgcttggtg aagagatgat acgtaagccc acccaacccg
    15481 ccggcaaaga gggccagcgc cagtagatcc tgccacagga cctctacgcc gacgcctttc
    15541 aaaaaactgc ctcgcacaat gttggtgaag tacatggccg ggaaaagatg ggcctgcacc
    15601 ttcgcccctc gtgttaaaga ggcaacggga accagaaggc cggaaaacaa aatggtcggg
    15661 atcatggcca caaccatcgt gatgatcaag gctgccattt gcgtctgcac cagcagcgaa
    15721 atcagcaggc cgattcccgt ggtacagcag acgaacagca ccgacgcgaa aaagaagaga
    15781 agaaagtgtc ctttaaacgg cacctgaaac aggcccacag ccatcagcca caacacgcag
    15841 acattcacga gggaaatgag aatgtagggg agcagcttcc cggtgagaaa ttcggctcga
    15901 ctgaccgtgg agctgtagat gttatagatc gagccggttt ctttttcccg cacaaccccg
    15961 agggccgtca gcagagggga ggcgagcatc aacgtgaaca tgaccagcgc cggtaccatg
    16021 gaccaggtac tccggacctc ttcattgtac agataccgaa cctctacact cagcggccgc
    16081 acgaggacgc cggcttgctc ccgggtgagg ccgcgcgagc gccgcaggaa atcgattaat
    16141 cgatcctccg taaacgcctg attgatcgcg atgacgtagc ccttggcgat atccgtgtgc
    16201 agtggaaagg tcccatccag caatgtctgc acggcgaccg cttctccggc gaccaattgt
    16261 tcctgaaacc gttcggggac gatgatggct gcccgaatct tcgtttcggt caacagccga
    16321 tccaggctgt gctcgtcgtg ggcataccct cgaaatgaaa aataccgcga ctgaatgaac
    16381 cgctggagat actcccggct gaactcactc tggtcccgat ccagcacggc aaagggaatg
    16441 tcttcgacgt ccagattgag cccgtacccg aacaccacga gccagagagc cggcaggaga
    16501 aaggccaaca ggaggaacag ccggtccctg gtggtctcct tccactcctt gagcgccaca
    16561 gcgctgatgc gttgcaggtt caggacgccc ccttcttctg cgccgcctgt tcgagcgcca
    16621 tcacacgtga aacaaacacg tcctccaagc tgagcatccg tggacgcacg gccgcaaccg
    16681 tcgtgtcagc gcggcccaac acctcccgca gacgcgcctc gtcacgagaa ggatcgcgcg
    16741 agagcacatg gatcttggtg ccgaagagcg cggcaccggt gaacccggcg gccgtcacct
    16801 gcgccagtgc cgcacccggc ttgtccacgg caatctccag cagttgcccc acttcgtgtt
    16861 ccacctgggt tttgagatcc gccggtgtcc cttcggccac gatatggccg gcatacatga
    16921 gcgcgagccg gtcgcaatgt tctgcttcgc tcagataatg ggtggtgatc aggatcgcga
    16981 cgccttcctc gcgggccaac cgcgtcagca aatcccagaa tcgacgacgg ccgatgggat
    17041 ccacgccgga cgtcggttcg tccaggaaca agacccgggg gctgtggacg agtgcgcacc
    17101 ccaacgcgag acgctgccgc acccccatgg gcaggcgacc tgtccggtca tgctcatagc
    17161 cgctgaggcc cgccatttcc acgatccacg ccatccgttg ctgcgcctgc cgtcgagcca
    17221 acccgtagat gtccgcaaac agccggatat tctcgatcac ggtcagatcc agatacaggg
    17281 agaaggcctg ggacatgtag ccgatacgtt ccttgatggc cccgctggcc gtccgcatgt
    17341 cggcgccggc cacgcggccc tctccgcccg atggcggcac aatccccgtc aacatcttga
    17401 tcaccgtggt tttgcctgcg ccgttggctc ccaggagtcc gaagatttcg ccttgttgca
    17461 tgtcaaaact gactcgatcc accgctcgaa atgaaccgaa gtcacgaatc aactctttag
    17521 cctcgacggc tggtccgtcg aactgcggcc tgttcgccgg gggggctgac tgacttgatc
    17581 gctccgatgc tctcgtctga ccgtcctgtt ctttcagcag gagcgccacg acgacatctt
    17641 ccagttccgg ttcatccgtg cggagatgtg ccaccggtaa aggatccagc acctgccgga
    17701 ttcctgcaac ggcggcctcc gcatcctgct ccggactgaa cacgtggagc gacgggccca
    17761 acgactccac ctgggcgtag cggtgtttca aacgttcaac cgcttcgagt tgcggcgttg
    17821 attcgaaggt aacgaccacg ccgggcacta acgattgcac gtctgcagga gtaccggaag
    17881 ccagcacgcg tccatgggag agaaacgaga gtcgatgaaa gcggaccgct tcgtccatgt
    17941 aggcggtcga gacgagcgcg gtcatgccct tcacggcctg ccattccgcg agaatggccc
    18001 agaaatcgcg gcgcgacacc gggtcgacac ccgtcgtcgg ctcgtcgaga atggcgagct
    18061 ccggctcatg aatcagcgtg cagatcaggc cgagcttctg cttcatgccg cccgaaagtt
    18121 gtttcatcaa ccggctgcga aagcgatcta agcgtgtgat gctcagcaac cgtgccttgc
    18181 gcgcctgaag gtccgtctcg ggaaccagcc gcaacttggc aaagaaatcg atgttctcct
    18241 cgacagaaag ttcggggtag agattgagtc ccaatccctg gggaagaaat ccgatccgcc
    18301 gcttcacctg ttccgctgcc cgttcggaat ccaagagggt cccaaacacg tcgacggagc
    18361 cctcctcgta ccccaacacc cccgcgatgg ccttcatcac gctgctcttg cccgcaccat
    18421 cgggaccgat gaggccatag atctcgccac gatgcaccgt gaagtccaag ccattgaccg
    18481 cacgatgctg cttgtatcgc ttgacgaagc cggacacccg gacgacctca tccgctgagg
    18541 acgcaggcgg gcccatcatc ggggcttcga ccaggcgacg tcgtctttcc agcggatcac
    18601 cgcgtccgcc ggcagacccg gcgtcagccg atgatctgga ttcgtcgtga ggtagagccg
    18661 gacggcatag atcaacttga cccgttcgtc cggagtttgg acttctttgg gcgtgaactc
    18721 cgccttggag gcgatgtatc ggaccgtggc gtcgaagggt tggtcgggga acgcgtccgt
    18781 gtggatgcgg gccggcaaat cgagacggac cttgccgatc tggagttccg ggacatagac
    18841 ctgcaggtac aggcggtcga ggtcgactaa ttcgaggagt ggtgccccgg tagccacgac
    18901 ttcccccacg tcgaccatgc gcgtggtcac cgtcccgctc gtcggcgcca caatcgtcag
    18961 atcatcgagc acgctgcgcg cctccgccag cgtggcgtcc gcctggtcgc gctgccgttc
    19021 gagcgcggcg acttccgctt ctttcgaccg gattcgctct cgccccaatt ccgcctgggc
    19081 cagttccttg ccggcttgat cgtgagcggc ctgcgcgaca gcaatctcgg tcacggcaat
    19141 tttccaccgc gcatcagcct gatccacttg ctgctccgac acggcctgct ggggaagcag
    19201 ggcacggatg cgctcggcgt cgcggcgggc ttcatattcg acggcgcggg ccttccggat
    19261 gacggcgcgc gcactctcaa ctttcgccgc ggccgcctcg atactcagag ggacttccag
    19321 gttcaggacc gcgagggccg tgtgagccgc ctccacctgt gccatcaggc tatcgaccag
    19381 ccgcgcggct tgatcgacct tcgctttggt ctgcgcatca tcgagccgaa tcaggatgct
    19441 gcctttgagc acctccgcgc cctcacgtgc cgccagctcg accacacgtc ccgggaactt
    19501 gctggccaca gtgacatggt cgccttcaat gcggccattg gcctgaatca gtccatccgg
    19561 caaccggttg tgccatacca gtcgatcgag gagtacatag ccggctatca cgacgacggc
    19621 gaggacggcg gcggccgtca tggaggtgcg gatagtcatg caatcagtct gtcctcgagg
    19681 cgtggaggca atcactcctg caaggcccca ttgccctcgc gtcgacactg tagtcgatag
    19741 gggacctttt tgccagagac gggcgcctcc ggcagctcgg cccaccatcg acctgctggc
    19801 tcagtggtct ccgtaccggt ccatccactt gcggatatgt tcaacggcct ctgctttctg
    19861 ttccgggcga agcgtcgcat gccactccgt tagcttcggc aacacccgct gcatcacgcg
    19921 cttctgttcg gcttggtgcc gatccatcaa ttggatcagt tgggcctgat ccagccggtc
    19981 gctctgcacc tgggcaatcg ccgcctccat gatcgccttg tgctctgcct gcgactcggc
    20041 acgagcggcc accatttcgt ctctgacggc catcaacttc gccttctgct gatcgtcgag
    20101 gtctaagtgt ttggcgatct tgtttgtcat ccaatccgcc cgctccgccg gcgtgtggtg
    20161 acggtgacaa ccggcgccta ccagcgcccc ggccagaacc agtactccga tcgcaacccg
    20221 aaccgtctgc tgcatcttca tgctgccctc cttcgtgaat gacctggtgc ttgagcgatg
    20281 gccctcatgc acatttaatc agtattcgaa ggcgacgtgg tagagtgccg gcgtcatatc
    20341 cactcccaat gcgccgagtt tctccttcat gggcgtgacg ctcttctcgt aggccttcca
    20401 atacagggtc tcgttttccc agatcgccac gttgatatag ttgaaccggc tgtccggctt
    20461 gagactcttg tgaaacgtgc cgctgatgaa tcctgcttgc gttgtgatgt gcgctttgac
    20521 gtcctgccac cactgtacaa attctgtttc tgtggcggcc gggacggaga atacgttgat
    20581 caatgtcacc ggcatgatgt tcctccttga taggattcac tcgaaactcg aacgggcctt
    20641 acggcgatgt gatccgatgt ccaccttcat gtgaagaggt ctggcggagt agggcacccg
    20701 ccaggtctct tcaggttatt gcgccttccg caggtcgatc acggttcctt cttcgttcaa
    20761 ctcgaccacg atatgcgacc cttccgcaat cggcttggtc ttcacttcca tccgctccag
    20821 cggaaattct tttacgcctt ccggggtcgc cagcttgatc acattcttcg tcgtgcccgc
    20881 atagatcaat ttcccgaaga tcagccggtg actgcctgcc ttgtgcttgt cttttccgtg
    20941 gtgatcgatg accatgcctt cttcattgat ccagagcgac acgtcatcgc cgacggccgc
    21001 atcggcaggg gcggtgttcg cgctgattgt atattgtccg gccggcgtct tcacatagac
    21061 caagccggat tggatcttgg tcaccgtccc atttacctga atgacgtaac ccggcttcgt
    21121 gcgcggatgc tcgtcgaagc tcatctcaac cgtaaagcga ttgatgtcga tcatctttcc
    21181 cgcttcgttc aattcgaccg tcaccggcgc cccttcttcc aaggccgata atttggaccg
    21241 tccggtttgc acatcaatgg ctttctctcc ttccggcgtc cacaccttga tctccctcct
    21301 gtccggcgca gtataggcca ggttgcccgt cacgaatcga tggctatgcg ccttgtctcc
    21361 cttccgatgg acgtcgatca cggcattgtt ttcattgacc tgcatctcta cgtcttcccc
    21421 cacctcaaga tttttgggcg tgagcgtgga cgcgattttc atcgtccccc atggagtctt
    21481 cacggtggtg atgcctgatt gcaccttcga caccacacca ctgaccttca tatgcgtcgc
    21541 gctcttcccg ccgccttcgg cggtgaatcc ggaagacgct cccagcgcca cactcagtac
    21601 cagcgaaccg agaacaatca ttgtgcgtgt catgatacga ctcctttcat tcctgactga
    21661 ggaccacctt gtctaacctc tgcacgatgg ccctcgtcag gcaacccgaa gcctctatgg
    21721 tgacccccgc gcgctgcatc tgcgacagca acgtggtgcc cgcctcatcg atgaacgtca
    21781 cttcccggag atcgatatgg catggggccg gctgatcgat ctcctgcttc acccaacagg
    21841 tccgcaactc gtcgacccag ggaccagcca gacggccgga cagcacgaag gtggttcccg
    21901 ggcttgtgtt cgacagcgta atcttcaaca tggtcgtgga cctctctgtc catcgaggac
    21961 ggccgggaag caacccggcc ccgccatgga tgatctcaga acatgcgcaa tgcgaagctc
    22021 gcctcccgcg gcttcctcac cggaagggcc gctcgctcgc cgaaccagcg ggcaatcagg
    22081 ccatcaagcg accacttgcc tccaccgatg atcagcaacg ccaggctcat accgatcacg
    22141 agcaggtgat attcgaaccc ttcaccggtc tgctgtccga accagttcat gaagaagccc
    22201 tggggcaagt gcaccgtcac aatcgccccc aacatgatca ccacaaagct cgccgccgtg
    22261 aaccgcgtga gcaggccagc aatcagcccg agactaccga tggactctcc gatgatgacg
    22321 aggaatgcga ccaaccaagg gaagcccatt ttttgagtaa aaaatcccat ggtgccctca
    22381 aacccgaacc ctccgtacca tcccaatagt ttctgggcgc catgggcgaa gatcacacct
    22441 cccagcacca cccgcaaaat caaaccggcc caggaatcat ctgttttgaa aaagctgtac
    22501 atgtcacacc tccttgatat gaattaccgc cggtgactcc gcacccattg cagaaccgcc
    22561 gtctccgtcc tgtctttcag caacagcccc gccacgaaga ggggcagggt caggagcatt
    22621 ccgtaccagc cgacccagag cgtgatgtct ttcatgaatt ccccccgttc ccttgtgcgt
    22681 tgctatgcag gggtaatggc aaggcctgtt ccaggcgctg gacgatcacg ccacatgggc
    22741 taactgcttg aaatcctgat ctgattgtcc gtgggtcgaa gaaaacgatg ggctgacaaa
    22801 agatgcgtga cgaagggcgt gcgacgagac gtcgtcaggt gacgaaacgg ctcgtcactc
    22861 tcgtgggcga gagagtccga gctttttgat tttcgatgtg agggtagtgc gtttgagacc
    22921 taatcgagcc gccgcaccat ccgggccgcc gatcacccat ctggtgtcgc gcagggttcg
    22981 gagaatttgg tcgcgttcgg catcctgcag ggtggctcct ggtgccgggg cctgccgcgc
    23041 ctcgatcttc agttcctgaa gcggcacctg aagctgcgtc cctggagtca ggatcacagc
    23101 tcgctcgacg agattctcca attcccgaat gttgccgggc cagtgatatc gggacagggc
    23161 ctccagggtc ggagcgggaa tggattcaat ggtcttcttc atgcgcgcag catagtgctg
    23221 tgcgaaatac cgcacgagca tcggaatgtc ctcccgccga tcccgtagcg ccggaaggtt
    23281 gagcggaaac acgttcagcc ggtaatacaa atcgccgcga aaccggcctt cctcgaccaa
    23341 tttggccagg tctcgattcg tggcagctac cagacggata tccacgcgaa tcgtgcgcgt
    23401 actcccgaga cgctcgaatt cctgctcctg cagcacccgg agcaatttgg attgcagctc
    23461 cagaggaatt tctcccactt cgtccagaaa gatcgtgccg ccatgggcca actcgaaccg
    23521 gccgactttt tgggcgatgg cgcccgtgaa tgcgccccgt tcgtggccga acaattcact
    23581 ctccaacaat ccggtcggaa tggcggcgca gttgagttta acgaacgtgc gcgcatgccg
    23641 gccactcaga cgatggatcg ccctggcaat gagttctttc ccggtaccgg tttcgcccag
    23701 aatcagcacc gtcgcgtcgg tgggcgccac gatctcgact tgccccaaaa tctgcttcaa
    23761 gggccggctg tcgccgatga tgtcgtcgaa gccgtgctcg acacggattt cctcttccag
    23821 atacaacttt tcctcggtca atcgatcttt aagcgtgtga atctcctgat acgccacagc
    23881 attgtcgacg gccaaggcga tctgccccgc cacctggctc aagaattcga gatcctgttc
    23941 gccaaaggct tgttcgtgat gactcgccag attcaggcag ccgatcacgc gatcgcgcga
    24001 cagcagcggc agtgagcaca tggagcggaa ccctttcctc accaggagtt gaggcacggc
    24061 atgcgaaaac gccttcaggt cagccagggt gttggcgacc gcggggcgcc tccgctcaaa
    24121 cgccagaccg gccagagacc cggcgacatc cgatagtgcc ccttcggtca acgcgccttc
    24181 gttgtcggga aaatcgagcg catgcagacg gacgcgctgc gtctggccgt cgcagaggat
    24241 caaactggcg tattcctgag ggaccagctc gcgcagacag aggctcaccg ccttgaacac
    24301 ctggcgcaga tccaaggtcg acgccatcga attcgtcatg cgcagcaaca gactgaagcg
    24361 atcccgttgc cgttccacgt cccgttgtga tgccgctgcc gcctcgcggt tcagcacgtt
    24421 ttctactgcc accgccactt ggcgtccgac ttgctgcatc aattccacgt ccgacgtgct
    24481 gtaggcgctc tgctcaagac tggaaaactc caaagatccc agtcgctgcg tcggggacgt
    24541 cagcggcacc agacaacatg aacgcactcc gtcctcgcac atcaattcga tgaccttcgg
    24601 ccagcgtcgt tctgtgggca gatcgttcag caagagtggc tgctgggttt cccacaccag
    24661 acccgccggc gtgtcttggg gatcgctttc gtgccctccg atgatctccg caggcacatt
    24721 cgcccgcagc acctgcagac gcatcacccc acgctgagaa tcatagagag acagtccgac
    24781 gaaattgacg ggtacgacca agggcagcag ccgcgcaaga tcctgcacta gcgcagacag
    24841 gtcggagtga ctggcaatgg cttccgcgac gcgcaatagc gcccgatacc gctcgatgcc
    24901 ggaggaatct ctgtcgctca ccgaggtcct gtcatgtgtc atcacggaat gagcaacgtc
    24961 gttcgtgacg ctgcagcctg cgttagtacc ccgcgaactt ttcgattcga atatcggtgt
    25021 cctcgacgtg agcgtctttc agaatggtcc gcaatgcggt caccatgccg ggcggaccga
    25081 ccacatagta catcggcttg tcgatctccg cgagatactt ggagagcaag cccgcattca
    25141 ggtaccccgt ttcgcctcgc caggcatgga gggatttctc gggttcggtc atggtaccca
    25201 caaaactata gtgacgattc ttgtcctgta aggactgcag ctcatccaaa aacgccgcat
    25261 cctccggtcg ccggttggag tagaacagca ccagacgctg cggtgattgc tgctgggcgg
    25321 catgcaccac catgctgcgg aaaggggtaa tcccgatgcc gccagctacc aagacagcgg
    25381 ggcgagtctg gtcactgtgc aacacgagtt tgccgaacgg cccttccatc cggacggttg
    25441 agccgatcgg catacgttgc aactcgcgct tgaaggcggt gtcgcggaga cgcgtcgcga
    25501 ccatgatggt gtcctcatgc ggggcgctgg cgatggaaaa ggctctgctg ttgccggccg
    25561 catcggtttc cgatggctgg agtaacgtca ggtccacgaa ctgtcctgga gtgaacacaa
    25621 actgagacgg cttggcgaaa tggaacgcca tcgttccctc cgcgatcaac cgtcgttcga
    25681 tcagtttcac cggaaagccg ctgtcatcca ttgcgtcact catccctgac ctcgcatgac
    25741 attacaggcg atacgtcccc accctgttac agcgacttgt gcgagccatc acaaaacgga
    25801 ggattcttcg tatgcttgca ctgacacaag gccagggttt tcttttcgac cgtcttaaac
    25861 tccatgggcg tgaagctggt tcccttgtga gatccatcgc aaaatggttg cttcttcgag
    25921 cggccgcagc ggcaccaata atatgtccct gcttccaatt ccaatacggc cggctgcttc
    25981 gctgcaatga ctggttcttc catgtgcatc tcctcctggt tgactgactg ttttcatgtc
    26041 cacatacgcc cttgccctgc ctagtcccgc tcgatgcatg tcatgaatcg cacatcgctt
    26101 gcccctggaa caggtgatga gctcgtcccg ccacgcggct gcatcacaga aaagcacatt
    26161 gccgcggaag aatgtgccca tctccagccg gctgttgcga cagaagggga cagcgtgaat
    26221 ctggccttca gcgctaaagc accagcggtn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    26281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    26341 nnnnnnnnnt tttccagatc gcctcgtccg catcgacata cagctccacc tcgttgccat
    26401 ccggatcccg aaggtacaga ctctgactga cggtgtggtc actcatgccg tcgatcgcga
    26461 tgccggcctg ctccagctcg cgtttagccg tcctcagttc gtccaggctg tccccgactt
    26521 tgatgccgat atggtagagc cctcgtctcc gtcccggcgg cggtcccggt gcatcgccga
    26581 cctggatcaa cagcaattca tggtgcgtgc ggccggatgt cagcgcggct gcagcgccat
    26641 tgaagatccg cccgacttcg tgaaacccta acaaatcgcg gtagaacgcc agcgcacgct
    26701 gcagatcttt cacgtaaaac acgacatgcc ctaaatagtg cgctttcatc gtcgtgactc
    26761 cttcctcggc ctgtcccgtt atcgaagcag cgcccgaacc gccgcgtgag ccagcaccac
    26821 atcaggctcc cgttgcaagg catcataata gttccggccg aaaccattgc cctcttcgga
    26881 aggggtcaac agggtccgca ccgacccgat caccgcggtg atctcccctt gatccgacgc
    26941 ctctttttct tcggacaact catccaatcg cgccattagt tgggagagcg gacgcaacca
    27001 ggcaaaccag gcatccccga ggactaactg aaaaaacgcg ccattggtag gaatgcgccc
    27061 atgaacccgc tcgtaggaga ctcgttcggc atccaacaac gccttatgaa ggcgcaacag
    27121 ggcgcgagac acgttatcca gatgcgccgt ggtatgatcc tgacccgaca tacgtccgcc
    27181 tccttacgat tggctctcca ttatcccgtc ggttcactgt cgagttgatg cgccttgcgg
    27241 ccgcctcggg cgagcggagc ggagatcagg cgcgcctcaa gcatgagccg agccaggtcc
    27301 gctgcgcggg tgacgagcgc ttccgcccct tcgcgcaatt cgcgactgcc ttgcacctcc
    27361 cgattgttcc gttccatgtc ttccgcactc cacccacgcg agtggtcgat aaagggaaat
    27421 tgcggaaact gacaaccgac ttcggcgaaa aaggtcatca attgtccggc cacgccctgc
    27481 acattatcct gtccgcccat gatgatgaag gcggccactt tgtccttgag cagatgccgg
    27541 ttcgcgatcg tctcttgatt ctgaatacag ttcagccgtt cgaccatttt gtaatacagg
    27601 ctgctggccc cgccccatct gatcggggtc gacacgagaa tcacgtctgc ccaatggaca
    27661 ataccttcat agactcgatc catttgatct gccgcatcca tttgggtgat cgaacagggc
    27721 caggtacagg cttcggccgc tttcgaataa aacccttcac aaggccggaa cgacaggtcc
    27781 cgcagccgga tgagctgcgt gtcgagctgc aagtgctcgc gcgcatgctc cagggccgct
    27841 tccagcagcg catcggacgc gctgtatcgc ggctcatccg tcgtcatggc cgtcgtggct
    27901 atcccaagca ctctaatggg accctcggca cgcacgatcg gacgggcgag gggatgcggc
    27961 accnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    28021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnngccaggg gcagacgaca
    28081 tagtcacctt cgagccgccc ctcgcccaac gggccgccga tgtgattgca gattccagag
    28141 atggctgcga acgtgccgtc cctatagctg agggcgagct tcgtattgcc gcagacaact
    28201 tcctgcagtg gcttcccctt cagttcctca accaacccga tctctgtcca cctcacatcc
    28261 ggcatgtcac attcctatcg gcgtccgcgg cagggctgcc cgtcacaagc gctgctcttc
    28321 aagatcatac acatcgaaat aggtgtaaac ggggcggtgg ctcgggacat acttcggaat
    28381 atagtcttcc atataggcct gtaccgcggg agccatctcg gaaagacgca gatcccgcat
    28441 cgtattattc cattcaatga tcgcctgccg atcctgcacc ttgctgtgct ccttgagcca
    28501 gtcgccgagt tcctcgtcgg tcgctcccgt tgcgacaacc tccttgaact ggtccggact
    28561 gatccccgta aaggtgaaca acaacgcggc gagcgaacaa ggccaatagt tatattcccc
    28621 gttgatgccc aggaggaatg cccggcactt atcggcacaa cgagcgccga taacataccc
    28681 tcccagcatt tccctcgggc tgcgaggata ggtcttggtg agatctttcg caagcgtgcg
    28741 aacctgctcc agattcttca tgtggtcgct ccttttcctg atccggcacg cgagggcttg
    28801 gcgaacgtga tgccggcctt ttggacttcc tgatagggca gcagccagac cagcgattcg
    28861 tccgacaagt ctcccacttg gatccggttt ccccaggggt cgcgaaaatc gcaacggaaa
    28921 tggggctcca tcttcagctt atatttcttg gtgagcttgc gccggacctc tttaatctga
    28981 tcggcatcgc gcaccatcag tccgaaatgc ttcatgcgat ccggctgcaa cgtcttcact
    29041 tcgaagatgg ccagaaattg atgctcgccc agtttgcacc aggcagcacc ctctcctccg
    29101 cgtaacatct ccaagccgaa cacatccgaa taaaacttca cggccttttt cgcgtcggtg
    29161 acttcgatga cgatatggtt gcatccgtag acctgaaccg acatgtccat tgctccttac
    29221 cgggttgtgt gctcgatggc ctggaggaag gtctcggccg gctgcgcacc ggacaccacg
    29281 gtttttccat tcaagaggaa gtacgggacc cctctgattc ccaactggcg accgcgtgcc
    29341 tcttcctgtc gcaccgcctc gaccccgtcc tggctctgca ggaaccgacc gaccgctgcc
    29401 ccgtccaggc cggcccgggc agcgagagac accagcacct cgtccgctcc gatattcagc
    29461 ccgtcggtga agtatccatg aaagagttct tccatcgcgg cgtcctgacg accctgttgc
    29521 tgagcaaacc agatcagccg atgggcctcg aaggtattcg gcgtgcgagc aatccggtcg
    29581 aaggcgaact cgatcccggc acttacgcct gcgcccgcaa ttcgattctg aatcgcctgc
    29641 atttcctccg gaccgccgaa ctttgcttca aggtatacac gacgatccat gccggccttc
    29701 ggcatggtcg gattcagttg gaacgggcgc caaaacacca gagcagagtc ctgtctgccc
    29761 gtcgattcca gcgcctgctc caaccgtcgc ttcccgacat aacaccaggg acagaccacg
    29821 tcggaataga cctcgatggt cagtaccggc gccgtcatga caaatgtccc atctttcccg
    29881 cttggtagtc ctgcacggcc tggataatct catctcgtgt gttcatcaca aacggaccgt
    29941 agcgcgcgat cggctccgca ataggcttgc cgctcagcac gaggatggtc gcctcctgtt
    30001 tcgcctccag aaccacacgc tcacctcgtt gtccgaacag cgcgatgtgc acgtcgtcca
    30061 ctgactgaga cccgttcacc accacctgcc catggagcac gaacagggac gaattgaacc
    30121 cctcgggcaa gtcgagttcc agccggtgcc ctgccgccaa acggaggtca tacaggtgca
    30181 ccggactaaa cgtcttcgcc ggtcctgcca caccgcgaaa ttctccggca atgacgcgga
    30241 gccggccggc gcctccgcca agttccacca tcggaatgtc gctgctcaac aacgtctgat
    30301 accgcggcgc cgtcattttg aacgccttgg gcagattcac ccacagttga accccttcca
    30361 agagaccgcc cttttctgca aattctttct cgtggagctc ctcgtgcacg acgcctgacg
    30421 cggccgtcat ccactgcaca tcgccgggcc cgataacacc gccgctcccc gtcgagtcac
    30481 gatgcgccac tttcccgtga tacatgatcg tcacggtctc gaagcctcga tgcggatgtt
    30541 cccccacacc aagccggcgc gtggtcggcg gaaattcttc ggggcccata tagtcgagca
    30601 tcaaaaaggg agacagttgc tcctcgaccc ctgcgcccgg aatcatattg cgcacgggaa
    30661 agccgtctcc aaccatatga tgggagcctg cctggtagac tccgacgagt tcttttgcgt
    30721 tcatggtttc tgttcgcatg tcggcctcct ttcttacgcc atctcccgca atgcttctgc
    30781 gagagccttc gttccccgca cgagtgactg agggcgctca tacctgacca cgtccttgga
    30841 aaacgcggta tacatctctt gaaacaatcc ggccgcttcg gtggaaaacc cgaatgaggt
    30901 gaatgtcggc accactgcgc tcaacggcgc cgcctgtacg gagacgcctc gtccgaaaat
    30961 ccggccaagc tcagaggcca cctcttcagg actgtactcc tctggacccg ctagttccac
    31021 aatcgcatgg ccctcgcctc cggcaatcaa tcgctccgct gccacacgac cgatgtcccg
    31081 ggtagatatc atcggcatcg acatcttcgg cggtataaac gacggcaaca gaccctccgc
    31141 cttggccatt ccgataccat tggcccaatt ctccataaag taacctggcc gcaagatcgt
    31201 gacgttgggc gccacggccg tgagccgatg ttctccataa cgagcggcgc gaatcggccc
    31261 cgtgccttcc ggaaggtggg cgccaataga agacagcagg accacatgcg caatcctggt
    31321 cgccttcacg gcctctgcgg tttggtctac ccgccgccgt tgctcggcca gccatgacgt
    31381 tgcaccatag ttcggcggca ccaggagata gacgcccgat gcgccttgca atgccttcgt
    31441 cagagccgcc tggtcatcca acgaggccac ggcgacttcc gctcccttcg cagcccaagt
    31501 agcaccgtga tcggccgacc gtaccactac tcgcaccggc tgcttgtgcg tcagcagggt
    31561 ctgcgcgacg accgatcccg tatgtcctgt cgcacccagt acaaccaaca tcgttgtcgt
    31621 tcccttcttt tcctgaattg ccccatgaca cgaccgctga accgtcggca tcggccggct
    31681 cccatcgccg gcaggagaag acggccaccc ccacttcgct gcaccccact ataatagttc
    31741 tagttagaac aaagtcaagt gcaaatatgc cggggctcct tcactttctg agttgatgca
    31801 tggacaggct gtaagacatg accacgatag aagacccacc gacgatacgc tcgagccgtt
    31861 acacgaggtg gggtcagtca gcagcagcgg gaggacgaga ttacgacgac gatcagcgga
    31921 gcagggaagc aggcgagggt ctacagatca atgacgaagg tgagagaggc tatttccgac
    31981 tcttgatcgc ccgttcgact tcgcggccag cctcacgagc cttgatggac tcacggcggt
    32041 cgtactgctt tttgcctttg gccagggcca gctccacttt cgcatgaccg cgtttcgaaa
    32101 agtagatgcg gagagggacg agagtgagtc ccttgagctg ggttttcccg atcagtttat
    32161 tgatctcctt gcgatgcagc aggagcttcc gtttgcggag aggatcatga ttcatcaggt
    32221 tgccatgcga gtaggggctg atgtggcaat ggttgaggta cacctcgcca tcatcgaccg
    32281 acgcataact gtcctggagg ttcacgcggc cctcgcgcag cgatttcacc tcggtgccgc
    32341 gcaggatcac gccggcctca aacttctctt cgacaaaata atcgtggtag gccttcctat
    32401 ttgtggccac caccttatac tgatcgtctg tatcgtgcgt tttggtcatg ttgctgaggc
    32461 gaccgctgtt tcactcgcgc gcattttgat atgatgccgc catgcgcgga cagagcagac
    32521 tcgattcctt cggcactatt ctagcaggtg tcgcccaccg gttgggcctc gagagcaaac
    32581 tcttcgaggc gcgtctacga cgccattggc cagagattgt gggcgaaccg atcgcgaccc
    32641 acacgcgccc cgatcaaatc cgattcaaga aacttcacgt ctacgtccat aactctgtct
    32701 ggctgcaaca actcacattc ctcaagccgg tacttctcga aaaagtgaat gggatggccg
    32761 gggagacgct cgtgacggaa atcgtcctgc gcatcgggga gttttccgcc gagcgcaaag
    32821 tgagcccgcc ggcagcgacg gttgaagagc ctgtccctca gccgagcgcc gaattgctcc
    32881 aggaaacggc cctgcatacg cagaacattc aggatcctgc tcttagggag caacttgcgg
    32941 ccgtcatggc gcaggcgttg tcggggatac cgccggactc gtcgcgacgg gccccttgaa
    33001 caactgcctc gaataggccg ccgttgccgc actgtctttg cccttgggca ccggcccgat
    33061 acggccttct tcttcctgtt cgtccaactt gtagtatccc cgtgccgaac cctcgaatcc
    33121 gtcccgcacc gccggatctt cgcccgtcac atacttatgc agcatttcag gctccgtcca
    33181 tccctcgtca gtgaagatgt aaatcgcgat gcgttggtag cgccctttcg gatcatctgc
    33241 ggtggtcgga cggatcttca tggggccgaa atttcttgtc tccgtcccca ccttgcggaa
    33301 tcgttcgatt aaggtttgga tctcggtgtc gctcgtccag gacgggacgt gcaccgcgac
    33361 gatgctacct tcctgggagc cgatgctgta gggaggaatg gaacgatccg gccggctcag
    33421 aaacataccg ccccagatca gagcaaagga gctgaacaga acgcccagcg ccagtttcac
    33481 gaccgtatcc aggggacgtt tcggaggacg gcctgcggaa gtcccggcgg acggcggttg
    33541 ctgctggttc ataaccatgg tgaaggacgc ctgaatccgc cggcgttcac ggagtgacta
    33601 ctcgccctct tcgggcaccc cttcttcacg ttcgacgagc cgcaccacgg cgacgacacg
    33661 gtcctcatca ccatccatat caagcagacg cacgccctgg gtgttgcgtc cgatttcacg
    33721 aatgtcgtcg accttgcagc gcagcacttt cccctgcgca gccatcagca tgatttcgtc
    33781 ctcatcccgg acctggagga atccaacggc cgcgccgttc cgttccgtag tcttgacgct
    33841 gatgatgccc ttgccgccac gtccctgcac gcgatactcg ttcaccggcg tgcgcttccc
    33901 gtaaccgcct tcggtcaccg tgagaatcgc cgtcgtggaa tcgggcgtga tggtctccat
    33961 gccgatcacc tcatcacccg cctccagagt aatgcctcgc acaccgtggg ccgtacgtcc
    34021 catggcccgc acatcttctt ccttgaaacg gatggtgatg ccctgcttcg tgcctaacag
    34081 aatttctcgc tgaccatcgg taagatcgac accgatcaat ttatcacccg catcaagcga
    34141 gagggcgatg atgccgccct ggcgaggatt gctgtaggcc gacagctccg tcttcttgat
    34201 gacgccctgc ttggtcccca tgatgacaaa ccggtcggcg cggtattctt tcaccggcag
    34261 cgtggctgtg actttctcgt ccttggagag tgccagcaga ttgaccaacg ctttgccctt
    34321 ggccgcccgg ctcgcctcgg ggatttcgtg caccttaagc cagtagacct tgcccgcatc
    34381 ggtaaagaac agcagcgagt catgcgtgga ggccgtgaag agagtttcaa cgaaatcctc
    34441 ttccttgatg cccatggcaa tcttcccttt gccgccccgc cgttgcgcgc gatagagcgt
    34501 gaccgcgttc cgcttgatgt acccggcatg cgaaatcgtc accacgactt cttcttcggc
    34561 gatcaagtct tcgagcgtca gttccgcttc ttccttgacg atcttcgtgc ggcgttcgtc
    34621 ctgatacttc tctttgatct ccgtcaattc atcccggatg atcttgcgca ccaacgcttc
    34681 actgccgagg actgaccgca ggtattcgat ggtcttcaac acttcgcgat actcttccac
    34741 caacttgtcg cgctcgagtt gcgtgagccg ctggagacgc atttcgagaa tcgcgttggc
    34801 ttggatttca gacaaccgga actgctgcat caaacccgcg cgcgccacat cgggcgactg
    34861 cgagcgccgg atcagggcaa tcacggcatc caggttgtcc agggcgatct tgagcccttc
    34921 gaggatatgg gcacgttctt ccgccttgcg caaatcatag gccgtgcgcc gcacgaccac
    34981 ttcgcggcga tgctcgacaa aggcttccag gatccgcttg aggttcagca cctccggccg
    35041 gttgttgacc agcgccagca tgttgacgcc gaaggtcgtc tgcaactgac tgtgtttata
    35101 caaattgttc agcactacga gcggaatttc attgcgcttc agttcgatca cgacccggac
    35161 cccttcgcga tcggactcgt cccggatatc ggaaatgccg gtcacgcggt cttcctgcgc
    35221 caggtcggca attttttcga tcagcttcg
//
LOCUS       DAOQPD010000034        35151 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_506_length_35151_cov_21.079154, whole genome shotgun sequence.
ACCESSION   DAOQPD010000034 DAOQPD010000000
VERSION     DAOQPD010000034.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 35151)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 35151)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35151
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_506_length_35151_cov_21.079154"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..667)
                     /locus_tag="PK063_09675"
     CDS             complement(<1..667)
                     /locus_tag="PK063_09675"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0006555 - methionine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HMZ97361.1"
                     /translation="MSREPRRLKDVLAQGQFAVTVEYNPPKGTNITHVVESAKSLVGR
                     VHGVNVTDNTAAIVRAGSLPVCRILYELGHDPVMQLTCRDRNRIAMQSDLMGAHMLGI
                     RNILCLTGDYPTVGDHKDAKPVYDLDSVQVMQLVTGLNNGKDYAGNKLDGSTDFTIGG
                     AVTPEADPLGPMLVKFEVKVRAGAQFFQTQAIYQPEQFKKFMDAVRPFKVKVLAGILL
                     LRNA"
     gene            complement(825..1685)
                     /gene="folD"
                     /locus_tag="PK063_09680"
     CDS             complement(825..1685)
                     /gene="folD"
                     /locus_tag="PK063_09680"
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase
                     FolD"
                     /protein_id="HMZ97362.1"
                     /translation="MAARIIDGKALAQQVRERLAVDSAAVLAKTGTKPGLATILVGDD
                     PASHVYVKNKQKACELAGIYVDDHKLPASTTQAELLALIEKKNADPKIHGILVQLPLP
                     KHIESRVVLEAVSPNKDADGFHPYNFGRLVEGNPVFEACTPKGVIKMIESAGVSIEGK
                     RAVVVGRSNIVGKPLALMLLQRNATVTICHSKTKDLAAVCREADLLLVAIGKAKFVTA
                     DMVREGAVVIDVGTNKGPDGKLCGDVDYEPVSQKAGWISPVPGGVGPMTIAMLLDNTV
                     ESAKRMAGMK"
     gene            1948..2970
                     /locus_tag="PK063_09685"
     CDS             1948..2970
                     /locus_tag="PK063_09685"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97363.1"
                     /translation="MTIFSFSSTRPRGRRNLGLTLAGAMGMVLASSWAWALQVSGLES
                     PHSFLADPPSRSYFISNINGDSNARDNNGFITKLSDDGRITAFKFIEGGRGEVTLHAP
                     KGMAVVDQVLYVTDVDTLRAFDKNTGKPVATVMLPRPADNKTTQSLVDVAADGKGHLY
                     LADQGGNAIYRVDLTSPLTLSLYVSGAHLAGPSGVAVNPKTGHIVVVSYDSGKIFDIT
                     PEGALTELASNGFFTGRFQNLSGVDFDRWGSMYVSDATKGKIWRMLPNNKFQVIAEYL
                     PGPSDLGIDRVNHLILVPYQDSNAAEVNGLESPTVSSGDRAKRTLADYGFGEPLKADK
                     EGSARK"
     gene            2967..3668
                     /locus_tag="PK063_09690"
     CDS             2967..3668
                     /locus_tag="PK063_09690"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97364.1"
                     /translation="MSQCVYCKQRKGKRSCPALTGLICSQCCGEHRLARISCPPDCEY
                     LDAGSDYQQKRLGEQFAPVRRELYRQLSVAGGEKAAALFNLIEVVTFGYFHDRRDGQD
                     AEVFAAIQALRRTLSPLHVPAAPMPVFAERLKKEYDTFVKQQPQQIADAGSAPEILDR
                     ALALLTEFSGQGFQSRRFLLGMIGYVKTFHPEIAEHLTKQHEAGRIVLPGQLTPPPQE
                     PAPHVHSPECRHHHH"
     gene            3860..5599
                     /locus_tag="PK063_09695"
     CDS             3860..5599
                     /locus_tag="PK063_09695"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ97365.1"
                     /translation="MHSFVSNLLAALPKGDALDDPAWSVRHRGILYILWLHVLGVPLY
                     GAYMGAGPSLYLGGGALLGAIAIAAQLPAVGRRLQAAIATYGLVTASALLVHLSSGRI
                     ELHFHFFVMMSVIVLYQDWLPFLVGLQFIVIDHGILGTLVPSMVYVHAEGQAHPWTWA
                     LIHGSFILAQCAALLYFWRVNEVAREEALQSEARTRMIIETALDAVVTTNVSGIITDW
                     NTQAELMFDVSRTDAIGQPLTTYLSTAHSSTAADAGVVLSGLVPGAILNRRVESIGRT
                     GSGQEFPVEIATSCLAIGGTQQFTTFIQNISERKQHEEALCRAKEAAESASQAKSQFL
                     ANMSHEIRTPMNGVLGMTELLLATQLNDRQRRYADTAHTSGTNLLHIINDILDFSKIE
                     AGRLVLEHIPYDLRQLLAETATIFHEQAGKKGLSLTLAIAQDIPMTLHGDPHRLRQIL
                     TNLISNALKFTTTGRIAISAAMDQARPEHVRIEVSDTGIGIPEDAQARIFDSFAQADG
                     STTRKYGGTGLGLAIVKQLVGMMGGHIEVTSVPGEGATFWFTILAYATAARSTASDPS
                     TSSTEALRRLHHK"
     gene            5612..6760
                     /locus_tag="PK063_09700"
     CDS             5612..6760
                     /locus_tag="PK063_09700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIST N-terminal domain-containing protein"
                     /protein_id="HMZ97366.1"
                     /translation="MHVATTSLKAGHAGIPAELAAHDSENSLLLLFGSSSLIDRPELI
                     QQVMAACPRSHVMGCSTAGEIHGVEISDDSLVVAAVRFEKTRLLTTQAAVHTPKDSYA
                     AGRAIAASLHQPSLRGVLVLSDGLNVNGSELVKGLNDTLGGSVVVTGGLAGDGTDFKR
                     TWVIKDRAPQSGYVTAIGFYGDHVRLGHGSKGGWDKFGPERRVTKSAGNILYELDGRP
                     ALQLYKEYLGDRAAGLPATGLLFPLAIRSSNTDGKVLVRTILAVDEAAQSMTFAGDLP
                     EGMLAQLMRANFDRLIQGASEAATLTLNNHEPAGSSSPTLSIAISCVGRRLVLGERTE
                     EEIEATLEILPNGSRQVGFYSYGEISPYASGACDLHNQTMTLTTITEL"
     gene            6766..>8930
                     /locus_tag="PK063_09705"
     CDS             6766..>8930
                     /locus_tag="PK063_09705"
                     /inference="COORDINATES: protein motif:HMM:NF013736.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ97367.1"
                     /translation="MHPLLTRQLKRLGLETTAAPTSLEAWQQLLERVSRSYIESDQGR
                     ELLERSIALSASEMQELNEQLRRTSESQLTQERDKLHTVLRSMGDGLCVVDRNWDIVL
                     LNPEGQRLWGLPEADVVGRRLPDMISLSYGTNLTEPIFTQMLLDETAQGHSFRTDDGI
                     LTSITGRSFPVSCVLAPIVRDGQAGGAVLVFRDISERKQAEDVRRHTESLLRQHQAAL
                     FGLTSNSIIQSGVLEPALREITRVTAATLGVRRCSIWLLRDDHSAIICKDLHDASNNS
                     HSCGMELLAAQFPKYFRELLTERVIDASDARTDPRTSEFTDTYLTPLGISSLLDIPIR
                     FKGKLVGVLCNEHVGTPRSWMLEEQQFSYAVASLVSLALEAVERLHAEGALRKSEGRT
                     RLIIDTALSSVISIDEQGRIIGWNTQAEQTFGWTRQEAIGRLMAETIIPASQREAHQR
                     GIRQFLKTGEGPILNKRIEISALRRDGTEFPIELAITPLRLENAYTFTAFVVDISERK
                     QAEEALRTSEARLTMTVQGSHIGIWDWNLTTDAVYFSPQWKSQLGHDDTTLPNAFQEW
                     QSRIHPEDRALVHQTVHSCLNGDRAQFELEHRLRHRDGSYRWILSRGTLIRDVYGVAA
                     RMVGIHIDTTDRKRTEEELRAAKEAAEAASKAKSEFLANMSHEIRTPMNGVLGTTELL
                     LNSTLTDKQRHLASTVHRSGRTLLAIINDILDFSKIEAG"
     assembly_gap    8931..9030
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <9031..10544
                     /locus_tag="PK063_09710"
     CDS             <9031..10544
                     /locus_tag="PK063_09710"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ97368.1"
                     /translation="LLAIINDILDFSKIEAGKLDLECVGFDLSQLLDESLELFMEAAR
                     RKHLHLTQQVDERVPRYLMGDPVRLRQILMNLLSNAMKFTETGGVSLTADYMSGTPTH
                     AQLRISVTDTGIGIPPAAKLRIFDAFAQADGSTTRRYGGTGLGLSIAKQLVGLMGGAI
                     TVESEPGRGSTFSFTARFELQPLGTGTDNGLPSYERLAKPHLTLEPPYGPSEPYPSSP
                     GTEAKRTGHRVARILIAEDSPVNREVAVGMLEILGYQVEMAENGRQALELVGRSQFDL
                     VLMDCQMPEMDGFTATGEIRRREAASGQRRLTIIALTANAMQGDREQCLAAGMDDYLT
                     KPYTQVQLQTVVQKWLDKQGTDRALAPVFSSTQAVSGESAPAAAAPPPSTPSMDPKAL
                     DGIRALQRPNRPDVLASVLRKYLDNSRDSVDALQDAIRANDPAGLQAVAHRLKSSSAQ
                     LGALAVAARCKELEALGAQKNLIEADRILVELQSEYAAACAVFRNEIAKEKSS"
     gene            10541..11290
                     /locus_tag="PK063_09715"
     CDS             10541..11290
                     /locus_tag="PK063_09715"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ97369.1"
                     /translation="MNPLTSGRSPYALVTDDDIIIRMFAREALEQAGWEVEEAENGLE
                     ACAAFKKCPPDVVLLDVMMPEMDGFQTCAALRQLPGGEHTPILIMTGLDDFESITKAY
                     DAGATDFIVKPLNAMLLTHRIRYMVRANQVLQELRASQATLTQARDAAMEGARLKSEF
                     LATMSHEIRTPMNGVLGMTDWLLETELTAEQLDCAQTIRSSGDSLMVIINDILDFSKI
                     ESGKLSLELLDLDLPKFVDRVLALFAERAQR"
     gene            11312..11788
                     /locus_tag="PK063_09720"
     CDS             11312..11788
                     /locus_tag="PK063_09720"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ97370.1"
                     /translation="MADDVPAALCGDPTRLQQILSNLLANAIKFSDRGTVSLTVDLDQ
                     RPSEQRLEFPATSYGELSSTASRISHVRFSVADNGIGIAPNAFAKLFQPFVQADGSTT
                     RKYGGTGLGLAICKQLVELMGGHIGAESEPGAGSVFRFTVPLQQPLADNERNKSAA"
     gene            12090..12980
                     /locus_tag="PK063_09725"
     CDS             12090..12980
                     /locus_tag="PK063_09725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3473 domain-containing protein"
                     /protein_id="HMZ97371.1"
                     /translation="MHCLTFDIEEHFQVSRFDSPIRRRHWGAFESRVTANTCKVLDLL
                     ARYDTKATFFVLGWVAERHPGLIKQIAECGHEIASHGYGHELVTAQTPELFRADVRQA
                     KQILEDLIGSPVQGYRAPGFTITRETLWALPILAEEGYTYDSSIVPIRHDHCGLPGSD
                     PWQHLKQTSSGPIWEVPPSTVNLGGVRIPIAGGSYFRLLPFPALCGLMRRIEQKGRPL
                     VMYFHPWELDPYQPHMEGPFLSKMFHYLNLDKMEFRMSTVMNSFRFGSIAEQIDLSPI
                     LPIDPTVFPSTPAEIAQDVV"
     gene            13143..13718
                     /locus_tag="PK063_09730"
     CDS             13143..13718
                     /locus_tag="PK063_09730"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97372.1"
                     /translation="MQKRQANLWGWWLRRVGLTVACFCVVLLPTTGFGQSIEDTVQFI
                     SDMANTHGFVRSLSCRNPKAAKPTKVTEIYSVIPTGTRLGTIELNHGHDDVNTGFTHF
                     NLQDIESIAYQGQDTRENNLVLYAVRISCNSNGPCILKTSFCTGAVTEVKGQFPEDTL
                     LFRSASHAERMAKALSHFLTLVRTQQQNQPF"
     gene            complement(13784..14437)
                     /locus_tag="PK063_09735"
     CDS             complement(13784..14437)
                     /locus_tag="PK063_09735"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HMZ97373.1"
                     /translation="MMTQSRWHNRFGCAAVMSLVLAIGMATTGLAADAPAKAGDSVNA
                     SNVRAVIKTKVGDIEIKFLPDVAPKHVENFIKLAKSGFYNGTIFHRVIPGFMIQGGDP
                     NTKDSLRKDAYGQGGPGHNVKAEFSDLPHKRGVVSMARAQDPDSAGSQFFIVVEESRF
                     LDRKYTIFGEVVKGIGVADKIVALPRVMCQTGAPSPADKGPCDNPIDRVEMTVTIIE"
     gene            complement(14467..15174)
                     /gene="rnc"
                     /locus_tag="PK063_09740"
     CDS             complement(14467..15174)
                     /gene="rnc"
                     /locus_tag="PK063_09740"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HMZ97374.1"
                     /translation="MTSATSIEAVQRLLGYRFRQPRLLEEALTHKSYSNERRTKDRTQ
                     NERLEFLGDAVLSLVMSEYLAAEFPGSNEGGLSKLKAHLVSEASLAKAARRMKLGRLL
                     RLGKGEELSKGREKHSLLADALEALIAAVYLDGGLEASRTFTLRVLEEELLAARAERA
                     RPGMDDYKTQLQELCQKRFESLPQYATVRESGPDHEKVFEVQLTIQGVMRGVGCGHSK
                     KEAEQMAAREALTQLTT"
     gene            complement(15202..16452)
                     /gene="fabF"
                     /locus_tag="PK063_09745"
     CDS             complement(15202..16452)
                     /gene="fabF"
                     /locus_tag="PK063_09745"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HMZ97375.1"
                     /translation="MHDRPVRRVVVTGLGLVTPLGTGVDKTWKALCAGESGVGRITRF
                     DPSGYDAQIAAEVKDFDPAQFIEKKEIKKMDTFIHYAVGASQLAVDDAGLKVSAEEAT
                     RVGVYIGSGIGGLGSIEHYHDVLKEKGPGRVSPFFIPMTIINLASGQVAIRVGAKGPN
                     SCAVTACATGNHCIGDAYRLIKRDDADVMIAGGAEAAITPLGVAGFASAKALSFRNTE
                     PAKASRPFDKDRDGFVLGEGAGVVVLEELEHARARGARIYAEVIGYAMNSDAYHITAP
                     PEEGEGAVRCMEMAIKDAGVAKTDIGYINAHGTSTMADAIETKAIKHVFGEQAYKIPV
                     SSTKSMTGHLLGAAGGIEAVFSILALHHGILPPTINLDHPDPACDLDYVPNKARATKT
                     QVVLSNSFGFGGVNACLLFRRCDQ"
     gene            complement(16464..16697)
                     /gene="acpP"
                     /locus_tag="PK063_09750"
     CDS             complement(16464..16697)
                     /gene="acpP"
                     /locus_tag="PK063_09750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005779510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HMZ97376.1"
                     /translation="MATVDERVKKIIAEQLGVEEEEVTLEAHFVEDLGADSLDTVELV
                     MALEEEFEIEIPDEDAEKILTVGKALDYIKEKA"
     gene            complement(16795..17538)
                     /gene="fabG"
                     /locus_tag="PK063_09755"
     CDS             complement(16795..17538)
                     /gene="fabG"
                     /locus_tag="PK063_09755"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HMZ97377.1"
                     /translation="MSLQGKVAIVTGGAQGIGRAIAEGLAEDGADIAVADLDPARSQD
                     AVAAIQKLGRRALSVKVNVSDWNDAKAMADQVMQEWGRIDILVNNAGITRDGLLLRMK
                     EEDWNLVLQVNLNGTFHCTKAVLLPMTKQRFGRIVNIASIVGAMGNVGQANYSASKAA
                     VIGFTKTAAREYASRAVTVNAVAPGFIDTAMTQGLPPEVKEALQKQIPLGRLGLPSDI
                     AAAVRFLVSDAASYITGQVLHVNGGMLMV"
     gene            complement(17569..18522)
                     /gene="fabD"
                     /locus_tag="PK063_09760"
     CDS             complement(17569..18522)
                     /gene="fabD"
                     /locus_tag="PK063_09760"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HMZ97378.1"
                     /translation="MTASAIGFLFPGQGSQSVGMGRGLYDAFPAVRAVYEEASTILGY
                     DAAQLCFEGPVERLNLTEHTQPALLVSSAAALKALEPAGLSPLAVAGHSLGEYSAVFA
                     AGGLSFRDAVALVQKRGRYMAEAVPPGTGLVAALLGLSAEVVKAVCQEASSVGVVAAA
                     NFNSPGQVVIAGEKVAVERAIDIAKSKGCKKAIPLPVSVPVHTPLMQGAADRLAAEFG
                     GVAWRDLTVPLINNAEAVALQRSEDIRASLVRQLPSSVRWEESVQTMAKMGVTTFLEI
                     GPGTVLTGLVKRILPGAVTANVHDQKSLDAALTTVGVNRQP"
     gene            complement(18629..19606)
                     /locus_tag="PK063_09765"
     CDS             complement(18629..19606)
                     /locus_tag="PK063_09765"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HMZ97379.1"
                     /translation="MIRGRITGTGSYAPERVMTNSDLEQLVATSDEWIRERTGIRERR
                     IAAPGQACSDLALIAAERALKAAGLSGSDLDLILLATCTGDMPLPSTACLLQHRLGAT
                     RAAACDISAACCGFVYALGVADAYVRTGMRHVLVVGSEVMSTITDWTDRNTCILFGDG
                     AGAAVVSAAEGERGILSSHLHSDGSLSDLIVVPGGGTRIPPSEAMVGERSQYIKMKGN
                     ETFKVAVRTLEEVARETLAAHQLSVDDLDLYIPHQANLRIIKAVADRLGLPLEKVVLN
                     MDRYGNTSAASIPIALDEAVRDGRVKDGQLVMFGAFGAGLTWASTLIRW"
     gene            complement(19603..20634)
                     /gene="plsX"
                     /locus_tag="PK063_09770"
     CDS             complement(19603..20634)
                     /gene="plsX"
                     /locus_tag="PK063_09770"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HMZ97380.1"
                     /translation="MKIAVDAMGGDHGPAPVIEGAMQAAQELGVGIILVGKEDELTAA
                     CRKLNCNDTRITIRHAPQVVEMHESPAAVARKKRDSSIWVATELVKSGEADAVVSPGN
                     TGASMVASFFVLGLIKGVERPAIATMLPTLTGSAIMLDVGANVDCSAQHLEQFALMGN
                     EFARHVYAKPNPRVGLLSIGEEDSKGNEVTKEAFKLLKTSPLNFIGNIEGREVYSGSA
                     DVVVCDGFIGNVALKISEGVADVIKKLLMKELSGSWLGRLAYPLIAKPLLNLKRKIDY
                     AEFGGAPLLGVNGTTMICHGRSSAKAIKNAIRRAKGLAETRLDELIQRDIEESLRRHQ
                     DERLEDKQA"
     gene            complement(20786..20971)
                     /gene="rpmF"
                     /locus_tag="PK063_09775"
     CDS             complement(20786..20971)
                     /gene="rpmF"
                     /locus_tag="PK063_09775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008678357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HMZ97381.1"
                     /translation="MPNPKHKHSRSRRDMRRTAKTRLVPPGFSLCPQCHELKLPHYTC
                     MNCGTYKGKAVIVVEES"
     gene            complement(21010..21681)
                     /locus_tag="PK063_09780"
     CDS             complement(21010..21681)
                     /locus_tag="PK063_09780"
                     /inference="COORDINATES: protein motif:HMM:NF014657.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HMZ97382.1"
                     /translation="MSVESRGPAACLLIDTGEDRLVMTVPMDMLNPAIVDIGPEGLPL
                     SCSASGPQLGLDEPEDKFGGPLAIQLELSQQEGRISVTGTLEGTAIRQCVRCLSEYAD
                     PLLVSLYAEYLPQASVAAKSAPAEQGRRNTRRGAQPVEPEEEADEEDELYWYQGDHLD
                     LVPMLREQVILAAPMQPICREDCPGLCPQCGQNLNERRCDCPPAQVPSPFRVLRGRGP
                     KGENA"
     gene            complement(21699..21956)
                     /gene="rpsR"
                     /locus_tag="PK063_09785"
     CDS             complement(21699..21956)
                     /gene="rpsR"
                     /locus_tag="PK063_09785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012096455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HMZ97383.1"
                     /translation="MERGDRGNSGGGGGRFFQRRKPCRFCVDKAPIDFKDVGLLRNFL
                     TERGRIVPRRISGNCLQHQRVLTVAVKRARQIALVSFAEER"
     gene            complement(21972..22373)
                     /locus_tag="PK063_09790"
     CDS             complement(21972..22373)
                     /locus_tag="PK063_09790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HMZ97384.1"
                     /translation="MAGFNKVILVGNLTRNPELRYTPSGTPVASFGLATSRRFKQGDE
                     LKEEVCFIDIVVFGKQAEHCGQYLSKGNGVIIDGRLQQRRWETEDGQKRSKHEVVAQG
                     VTFLPKRGEAGAGADSGGLHDEPPSYEDEQF"
     gene            complement(22357..22716)
                     /gene="rpsF"
                     /locus_tag="PK063_09795"
     CDS             complement(22357..22716)
                     /gene="rpsF"
                     /locus_tag="PK063_09795"
                     /inference="COORDINATES: protein motif:HMM:TIGR00166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HMZ97385.1"
                     /translation="MELYESLFIIRPTLSDEETTTLIEKMKGIVTKNGATLVRAENWG
                     RKKLAYEIKRERKGTYVYFYFQGPGTTIADLERAYRLEDSIIKFLTVKLEQEPAPPRG
                     APVAAPAAQGATVGGVQ"
     gene            complement(22894..24486)
                     /locus_tag="PK063_09800"
     CDS             complement(22894..24486)
                     /locus_tag="PK063_09800"
                     /inference="COORDINATES: protein motif:HMM:NF024850.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HMZ97386.1"
                     /translation="MSRTWVTVGLLIMVSCLAQPSTAAWIDPLTPEERQGRNLYHYGK
                     AGIADPVAVNLQGVEGGVPPALFRCAGCHGHRGEGSQEGGLRVPPLTVSVLRRAREGT
                     SAGRPRAGYTDEALGKAITQGIDASGHALHPSMPRYQLTSDQVAKLIAYLTRLGEEAD
                     TDPGVSAEVVTIGAALPLTGPLAQIGQDVAATLRGALRRVNEQGGVYGRHIELIVEDS
                     RGDPAQTAQAVSRLIEIHQVFALVGSFEPAGGGRERFEQDQIPSIFPLTQSPQLSDPP
                     DPSIFYALPGFDLQFRSLMDFFASRTMPLTGTAQPRLALVHRNGDSNSEALRGALEQI
                     RHHALNLAMNYEYSTGRLAVLALVAQLEQQAIDAVVFLGDGEDLVSIAHELGRRGMSP
                     IVLSATGMVGPRARAVPSSLLPRIFLVTPIDPPTEREVTYLRALSEQPSLSSIGFARI
                     AHGAVSLLAESVKQAGRRLDRQAMVDALEACREYDTGAGFSVTYGVHRRLGRVASKVV
                     GLMSDPPYISPVTGWMVPEGEP"
     gene            complement(24519..25100)
                     /locus_tag="PK063_09805"
     CDS             complement(24519..25100)
                     /locus_tag="PK063_09805"
                     /inference="COORDINATES: protein motif:HMM:NF014667.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SCO family protein"
                     /protein_id="HMZ97387.1"
                     /translation="MMLRFVPAAMLLWLCGAHAAPAWSGVTPPSIPDVEVIDQDGVPH
                     RFYGDMVKGKTVVINFIYTTCKTSCPAATGLLSGVYHRLQAAERPVTLLSVTVDPVHD
                     RPTRLKAYAAQFGAGKGWYFLTGAPADVARILASLQVSASNKAEHPAIVVIGNEAAGI
                     WTRLYGEASVPMVMDGLDATAGPPALTPSGISQ"
     gene            complement(25114..27078)
                     /locus_tag="PK063_09810"
     CDS             complement(25114..27078)
                     /locus_tag="PK063_09810"
                     /inference="COORDINATES: protein motif:HMM:NF014312.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome D1 domain-containing protein"
                     /protein_id="HMZ97388.1"
                     /translation="MRNILVGARGSLPAFLLVAAPAIVGAGETAPSHPVQRFEQNGLA
                     IELTVVPQDGPSETGAELTAGQTATVKVALMDAKSGSPVVGIRPKGWMVGRPSEMAAD
                     EHSCVEKIRRLAGGRLGARAEVDLNRYVIVTMNHDKTVSVIDPQVEFGATKLESLVTL
                     PGNGADWVLSPDQSYLYVTIPGEDAVAVIETRTRKLIQTIALDKGSRPGRILWQPDSR
                     RLWVGLDGTGQVAVLDGEGHRRLKTVTVGRGLHTLAAIPDGRFIYVTNSQSDSVSVID
                     TQAMAPVVSVPVGKTPVAVTYSSAARRLYVGGVNGGDIVAIDPSTHRLVGRIPMAAGV
                     VALATEPQGRFVFAVNQVESSLSVIDTATSTVTATAHVVKDPDQIVFTQRYAYVRGIE
                     SEKFTLLDLREARNGKLVPLDVQAGRQAPSAAPQELGVAPMIVPTPEGNAVMIANAPD
                     ATLHYYQEGMMAPSGTFSNYRRMPRGVLVLDRSLREVAPGVYQATVTLPHPGRFDVPL
                     LLDQPRMSHCFQVTVQESPASTATAPGPRPVRIQARFESDLVSAHVPASLSFDLLDAT
                     TQEPIVGLHDVQVLIFEPPGTWQQRRWAQEERAGRYVITQSFPHAGEYRLLVQSPSRH
                     LRFSDAPPVLLTVGPPMSVSTGSSEQALKP"
     gene            complement(27087..32945)
                     /locus_tag="PK063_09815"
     CDS             complement(27087..32945)
                     /locus_tag="PK063_09815"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97389.1"
                     /translation="MPGEDVQGAPSRPHVCTFSVVAKTAAIVSLSLLWWGCAKPKMPE
                     SQQVVKPACERTITAEVVALDQVYYYNRFGAFNPAGIMFALRRDVVHADEEDLLNGDL
                     DNRSDEQEKAITLQHGPADLGLAGNVKLRSDKRPRPLVLRANEGDCLEVTFTNLLSPE
                     TNGQEVMLDPEKRLSRPDKRVTAVSDSDEPSTRHASMHVNGLSLVDSIDSQGANVGRN
                     GWHDQSGNKTDGRCSSNRSDFGKDLCALAAPGETRTYRWYAKKEGTFFLYSMGAPAGG
                     EGDGGQVGLGLFGAINVQPRGAKWYRSQVTEKDLKAASYKQETKFGQPVIDYEATYKN
                     EPHAGDPILNMLKCDPRDNRQCELVHSDLNAVIDIDRENGCEKMGEGNACGKPYREFT
                     VIFHDEITAVQAFDEIREEGSPLSSLRDGMGINYGASGVGSMVVANRNKLGPARDCVE
                     CKLEEFFLTSWVNGDPAMVVGYERGKGGSYKKDGNGRFVMQARYPDDPSNVHHSYLGD
                     PVRFRNMHAGPKETHVFHLHAHQWVEDKHDPLSHYLDSQTISPGTTFSYEVHYGGSGN
                     RNLGPGDSIFHCHLYPHFAQGMWELWRTHDVFENGGYDRRLKDHDIAGGTPTPAIVPL
                     PRTPLPPMPTPTFKGYPFYIAGEIGHRPPQPPLDLEGGDDAGTLRRHVVAGGTVHDAL
                     DAQGPKEMKQAPPMNHDLFDKGRQQSAQIAARVGTQNTDKDLVGLARELVTAKLDVKA
                     TAGTTDEKAAMKFHAGMSQVNGASAVRPGDPGWTYSPYNWEAPGYVTCLSNGLCDDPH
                     GTRVLFHVNGGGNIAEAKRGEGESGAPFSNPCPKQFIDEKGGVHDVKTREYRAVYIQM
                     NMTVNKSGWHDPQARFPILEQDVKETLDGTRPTEPLFFRAQSGECVVFHATNLIPSNL
                     NLDDFQVYTPTDTIGQHIHLVKFDVTSSDGSGNGWNYEDGTLAADEVRERILAYNKTN
                     PAQRLKPRTHRLFLRKGQLGATENGAMAGDPRGLCSDITGQAADDHDPVGHPWCGAQT
                     TTQRWWADPVLNGKPGDKGTKDRTMRTVFTHDHFGPSSHQHHGFYAALVVEPRNSKWY
                     FPDGQLMGGTDSKGVPEAVNGRNDGGPTSYAANVVVRTQGKACITPDKDGILCSDALD
                     SKGSIDAERTGREFNLAFADFAIVYDKDNQPVNPPSQIEGGLRTPILPGRIPVPEGIS
                     TKDPGSQLINYRNEPIPLRIGTQDKDGHQFKQLPVDQEKGDLAHAFSSTVHKDQKSVD
                     ERLFTEPSGKGRMPGDPATPLLRAYEGDHVQIRLIQGAQEEQHVFTMHGSKWLAQPDS
                     PNTGYVNAQTIGISEHFEFNDRVVDFMPFGRSNGHKSLGGAGEHTSIDHLYSSAATDN
                     LWDGQWGLMRVYSRTEDEPGLVRLPGNAEKTHDVLASAFMQNLDELLDRESLDVSDDD
                     AGNEAGQNLAQSDALEAFCQKSGQAQLTRSYEVEAWLAKDLLPSGKLVYNEHFGIADP
                     NAIIFVDASEKAMLRSGSKRPEPLILRARAGDCIRVTLTNHLPAAMQDGPDYPETWSY
                     NMVPPIVPGFSFNQVRSSSRVGLHPQLVDYNLLKSDGAHVGLNDDSTVAPGVSKTYLW
                     YAGDIVPNKKGTRIVGIPHEFGAIGLQDMGDVIKHASHGAIGALLIEPQCSRWDTVPS
                     TGNAEAVVTYWKPESASGRQGRHLKRQICPAEPKLDSGKLYRFKEMVLLYQDNLSVQQ
                     YGQPVPNLRNGDDSEDSGQKGFNYRTEPLWARLGASAADEPETMSQFDWSNVLSSTVP
                     HFRCEADFANKKYCDPETPLFTAKAGEPVRFRVVHPGGHPRQHAFTVFGHDWVPSPWI
                     DASKAMGWNQDGLTRVGSAGGIGPGRDVNILTTAGGDCKVPGDYLYRTQEGFMFGGGL
                     WGIFRVEENPGLRWYQPAWAWAGNLFGYETNGVASADLCKVHAANEAPIVQP"
     gene            complement(33034..34590)
                     /locus_tag="PK063_09820"
     CDS             complement(33034..34590)
                     /locus_tag="PK063_09820"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97390.1"
                     /translation="MRVPSTVTVWMIGVLVLLGIAPPRHALSQAVIPFHIVGHIQRLT
                     LDSPADPLSGAKLTVNGVEVVLPKNLVIQLPAAYFTAQQLFDKAQGVSKKYGESGLAL
                     SDKFPPLAAFEADVSGNIVNGLYIAGLVTISQQSLNTGAGFIHHIDTATGMMCVGGSP
                     TAAACAGNDTRIRLNDPALDASDPFAGDGRYGKPNPAPPPVGLDDPNSRYPDPRFTVD
                     QGNPTVHALTGYPMCVPRATNDAQCPSQNRPAELTFVMDSVDLVPPVKFGNNAIKACP
                     SCDANKQAPVRVGDYITFSGTRARDPLAGDFLSVHTLVANVGIYTKPGGRAYVSLEES
                     LLGTRGPVVDCGAAAECQDRLKVEGFTTDPSRRVSVYAVDVVPGGVPKVRLLHSTEKD
                     QAVFGRFRYVPPLTAATLFDFNGNLKGATRELMVRIDDPAPLSDGSDVPSAPKAAHGL
                     TAGIYVAPVGEYIFPEPTGVQGGAQPALNFQCLAFLANGWALPDSGLPNIPRLTPWPG
                     VATPTFSCTQ"
BASE COUNT         7341 a        10959 c         9418 g         7333 t
ORIGIN      
        1 tggcattgcg cagcagcaga attcccgcga gcaccttcac cttgaacgga cgcactgcgt
       61 ccatgaactt cttgaattgt tccggctgat aaatcgcctg ggtctggaaa aactgcgcgc
      121 cggcgcgcac cttgacttca aatttgacca gcatcggccc cagcggatct gcttccggcg
      181 tgaccgcccc gccgatggta aagtcggtag aaccatcgag cttgttgccc gcatagtcct
      241 tgccattatt caatccggtc accaactgca tgacttgcac ggaatccagg tcatacaccg
      301 gcttggcgtc cttatggtcc cccacggtgg ggtagtcccc ggtcaagcag aggatgttgc
      361 ggatgcccaa catatgggcg cccatgaggt ctgactgcat cgcgatgcga ttgcggtccc
      421 ggcaggtcaa ctgcatcacc gggtcatggc ccagttcata cagaatccgg cacactggca
      481 gtgacccggc ccgcacgatc gccgcagtgt tgtcagtgac attgaccccg tgcacgcggc
      541 cgaccagcga ctttgcgctc tcgaccacat gggtgatgtt ggtacccttc ggcgggttat
      601 attccaccgt gacggcaaat tgcccctgcg ccagcacatc cttgagtcgc cgcggctccc
      661 ggctcatcga gatcttccct gcatggtttg tggtctccct atcctccgag tcatcttccc
      721 ctacctcact tgaaagaggc gggtcgggac gtcccgatta cgcgcatcga ccgagcacat
      781 tctgatcgta cgcggtctgc gagcaacggc gcggcccgat ctgcctattt catgcctgcc
      841 attctcttag cagattcaac ggtattgtcg agcaacatcg caatcgtcat cggcccgacg
      901 ccgcctggta ccggactaat ccacccggcc ttctggctca ccggctcata atcgacatct
      961 ccgcagagct tgccatccgg ccccttgttg gtacccacgt cgatgacgac cgccccctct
     1021 cgtaccatat ccgccgtcac aaacttggcc ttcccgatcg ccaccagcag cagatccgcc
     1081 tcgcggcaga ccgcggcaag atccttcgtc ttcgaatggc aaatcgtcac ggtggcattg
     1141 cgttgcagca gcatcaacgc caacggcttg cccacgatat tgcttcgccc cacaaccacg
     1201 gcgcgcttgc cttcgatgga aaccccggcc gattcgatca tcttgatgac ccccttcggc
     1261 gtacaggctt caaacaccgg gttgccttcg accaaccggc cgaagttgta tggatggaat
     1321 ccgtcagcat ccttgttcgg cgagaccgct tccagcacca cgcggctctc gatatgctta
     1381 ggcagcggca gctggaccag gatgccgtga atcttcggat cggcgttctt cttttcgatc
     1441 aacgctaaaa gttccgcctg ggtcgtactg gcgggcagct tgtggtcgtc cacataaatc
     1501 ccggccagtt cacaggcttt ctgtttattc ttgacgtaga cgtgcgacgc aggatcgtca
     1561 cccacgagga tcgtggccag gcccggcttg gtgcccgttt tagccagaac cgccgcagag
     1621 tcaaccgcca accgttcacg cacctgttgc gccaatgctt tcccgtcgat aattcgtgcc
     1681 gccacaatat cctccctggc ctgagtagaa gcgaaaagtg agggcaccat agcaggcaat
     1741 ttttcaacaa gtcaacgctg gaggcggcgg gacgcatctg atgaaagccc tcgattccac
     1801 agggacctcg caaggtcgtg ccgttgtctg tccgtccggc cttctccgct cgctcatacg
     1861 cgatgttgct gcttccttga caggttccga gacccttggc tacgatgcat caggacaatc
     1921 tgtgcgacca tcttcgttga tgattccatg accatctttt ccttctcttc gacacggccg
     1981 agaggccgtc gcaaccttgg actgactctt gcgggcgcca tgggaatggt gctggcctcc
     2041 tcatgggcct gggccctgca agtcagcgga ttggaatctc cacacagctt tctggctgat
     2101 cccccctcga ggtcctattt catttccaac atcaatgggg acagcaacgc ccgggataac
     2161 aacgggttca ttaccaagct gagtgacgat ggtcgcatta ccgccttcaa gttcatcgaa
     2221 ggaggtcgcg gagaggtcac gctccatgcc cccaaaggca tggccgtcgt cgatcaggta
     2281 ctgtatgtca cggatgtcga caccctgcgc gcgtttgaca agaacacggg caaacccgtc
     2341 gcgacggtaa tgctcccccg gcccgccgac aacaagacca cccagtcgct cgtggatgtg
     2401 gctgccgatg gaaagggcca tttgtatctc gccgaccagg gcggcaatgc aatttatcgg
     2461 gtcgatctga cctccccatt gacgctgtct ctttatgtgt ccggagccca tttggccggt
     2521 ccttcaggag tggccgtgaa tcccaaaacc gggcatatcg tcgtggtgag ttatgattcc
     2581 ggcaagattt tcgacattac tccggaagga gccctgaccg aattggcctc caacggattt
     2641 tttacgggac gctttcaaaa ccttagcgga gtcgatttcg atcgctgggg aagcatgtac
     2701 gtatcagatg cgaccaaagg caagatctgg cgcatgttgc cgaacaacaa atttcaagtc
     2761 atcgcggaat atctgcccgg gccgtcagac ctcggcatcg accgcgtgaa tcacttgatt
     2821 ctcgtgccgt accaggactc gaatgcggcc gaggtcaacg gcctcgaatc tcccacggtg
     2881 tcatctggtg atcgtgccaa acgcaccttg gcggattacg ggtttggtga acctctgaaa
     2941 gctgacaagg aaggatcggc ccgcaaatga gccagtgtgt ctactgtaag cagcgcaaag
     3001 ggaaacgttc ctgtccggcc ctcacggggc tgatttgcag ccaatgttgc ggggagcatc
     3061 gcctggcccg tatctcctgc cctcctgatt gcgagtacct cgacgcgggg agcgactatc
     3121 aacagaaacg gctcggcgaa cagttcgccc cggtccgtcg ggaactctat cgtcagctca
     3181 gcgtcgccgg cggcgaaaag gcggcagcct tgttcaacct gatcgaagtc gtgacattcg
     3241 gctatttcca tgaccggcgg gatgggcagg atgccgaagt cttcgcagcc attcaagcgt
     3301 tgcgccgcac cctcagtcct ctccatgtgc ccgccgcgcc aatgccggtc tttgcggaac
     3361 gtctcaagaa agaatatgac acgttcgtca agcagcaacc gcagcaaatc gccgacgccg
     3421 gctcagcccc ggaaattctc gatcgcgcgt tggcgctcct cacggaattt tccggccaag
     3481 ggttccaatc acgccgcttc cttcttggca tgatcggcta tgtcaaaacc ttccaccccg
     3541 aaattgccga acatctcacc aagcagcatg aagccggtcg cattgtgctg cccgggcagc
     3601 tgactccgcc gcctcaggaa cccgcacccc atgtccatag cccggagtgc cgtcatcacc
     3661 accactgatc acctgccgct cgcccaacca tgagagacgc ccattcgccg tttgagcagg
     3721 ttgtctaccg ctagattccc ccttcgcttt ccctcgtttt ccctttagtt acaccccgtt
     3781 tctgccgata cagtcgggcc aggatttaca cctgcgcaag acacaaatcc ggactgcgcg
     3841 cgcaacgcat tgaaatttca tgcattcatt tgtcagtaat ctcttagccg ccttgccgaa
     3901 gggagatgcg ctggacgacc cggcctggtc cgtccgtcac cgcggcattc tctatatcct
     3961 ctggttgcac gttcttggcg ttcccctcta cggcgcctat atgggcgccg ggcccagcct
     4021 ttatctcggc ggtggagccc tcctcggcgc cattgcgatc gccgcacagc ttccggcagt
     4081 cggtcgtcgg cttcaggccg ccattgccac ctatggattg gtcacagcct cggcgctctt
     4141 ggtgcacctc tccagcggac gcatcgaact gcactttcat ttttttgtga tgatgtccgt
     4201 gatcgtgctg taccaggatt ggctcccgtt tctggttgga ctgcagttca tcgtcatcga
     4261 ccatgggatt ctcggcaccc tggtgcccag catggtgtat gtccatgccg aagggcaggc
     4321 gcacccgtgg acctgggcac tgattcacgg cagcttcatt ctggctcaat gcgcagcgct
     4381 cctctatttt tggcgtgtca acgaggtcgc tcgcgaggaa gccctgcaga gtgaggcccg
     4441 cacccggatg atcatcgaaa ccgccctcga cgccgtcgtc acgacgaacg tctccggcat
     4501 cattaccgac tggaacaccc aggctgaatt gatgttcgac gtatcccgca ccgacgccat
     4561 cggacaaccc ctgaccacct atctctccac ggcccactct tcaaccgcgg ccgatgccgg
     4621 cgtggtgctt tccggactgg ttcccggagc gattctcaac cgtcgagtgg agagcatcgg
     4681 ccggaccggt tccggccagg aatttcccgt cgagatcgcc accagctgcc tcgccatcgg
     4741 aggaactcaa cagttcacca ccttcatcca gaatatttcc gaacgcaagc agcacgagga
     4801 agccttatgc cgggccaagg aggcggcgga atcggccagt caggcgaagt cccaattcct
     4861 ggctaatatg agtcacgaga tccgaacccc gatgaacggg gtactcggca tgacggaatt
     4921 actcctcgcg acgcagctca acgaccggca acgacgatat gccgacaccg cgcacacatc
     4981 cgggaccaac ttactgcaca tcatcaatga catcctggat ttttcgaaga tcgaagccgg
     5041 acgcttggtc ttggagcaca tcccctacga cttgcgccaa ctgctggccg aaaccgcgac
     5101 catctttcac gagcaggcag ggaaaaaagg gctgtcgttg accctggcga ttgcgcaaga
     5161 catccccatg accctccacg gagacccgca ccgcctgcgg cagatcctca cgaacctcat
     5221 cagcaatgcg ctcaaattca caaccaccgg acggattgcc atctcggcag ccatggatca
     5281 ggcccggcct gaacatgtac ggatcgaggt gtccgacacg ggaatcggca ttccagaaga
     5341 cgctcaggct cgaatcttcg attcatttgc gcaagctgac ggatcgacta cgagaaaata
     5401 tggcgggacc gggctcggcc tcgccattgt gaagcaatta gtcggcatga tgggcgggca
     5461 tattgaagtg accagtgtgc ccggagaggg agccaccttc tggtttacga tcctcgcgta
     5521 tgccaccgca gcacgatcga ctgcctccga tccatccacc tcttccacgg aggcgctgcg
     5581 gcgcctgcac cataagtaag gagaacatcc catgcatgtc gcaaccacct ctctgaaagc
     5641 cggtcatgcc ggtattcctg ctgaactggc cgctcacgat tcggagaaca gtcttctcct
     5701 gctgttcgga tcctcaagtc tcattgatcg accggagctc attcagcaag tgatggccgc
     5761 ttgccctcga agccatgtga tgggctgctc tacggcggga gaaattcatg gtgttgaaat
     5821 ctcggatgac agcctggtcg tcgcggccgt gcgctttgag aagacgcgcc tcctcaccac
     5881 ccaggcggcg gttcacaccc ccaaagattc gtacgcggcc ggacgcgcca ttgccgcgag
     5941 ccttcatcag ccctcactca gaggcgtgtt agtgctctct gatgggttga atgtcaatgg
     6001 cagcgaactc gtgaagggac tgaatgacac cctgggaggc tccgttgtcg tgaccggggg
     6061 tttggccggc gatggaaccg acttcaagcg gacatgggtc atcaaagacc gtgcgccgca
     6121 gagcgggtat gtcaccgcca tcggcttcta tggcgaccat gtccgcttgg gccatggctc
     6181 aaagggcgga tgggataagt tcggccctga gcggcgggtg actaaatcgg caggcaacat
     6241 tctctacgaa ctcgatgggc gccctgccct gcaactctat aaagagtatc tcggtgaccg
     6301 agccgccggg ctcccggcca ccggcctgct cttccccctc gccatcagat cttcgaacac
     6361 cgatgggaaa gtcctggtcc ggaccatcct ggctgtcgat gaagcggcac aatccatgac
     6421 cttcgcgggg gatttgccgg agggcatgct cgcccagttg atgcgtgcca actttgaccg
     6481 cttgattcag ggagcttctg aagcggcaac cctcaccctg aacaatcatg aacctgcggg
     6541 cagctcttcc cccacgctgt cgatcgcgat cagctgcgtc ggacggcggt tggtgctcgg
     6601 ggaacgaacg gaagaagaaa tcgaagcgac gctggaaatt ctgcccaatg gaagccgcca
     6661 agtcggattc tattcctatg gggaaatttc tccctatgcc agcggagcct gcgatcttca
     6721 caatcaaacc atgacgttga ccacgattac cgaattgtaa tctgtatgca tccgctgctc
     6781 acacgacaac tcaagcggtt gggactggag actaccgccg cccccacctc gcttgaggcc
     6841 tggcagcaac tgcttgaacg cgtcagccgg agctacatcg agtccgacca gggacgcgaa
     6901 ctgctcgaac gctcgattgc cctgtccgcc agcgagatgc aggaactgaa cgagcagctt
     6961 cgccgcacat cagaaagtca gttgacccag gagcgggaca aactccacac cgtgcttcgt
     7021 tccatgggtg acggactgtg cgtcgtggat cgaaactggg acatcgtcct gctcaatcct
     7081 gaggggcagc gtttgtgggg acttcccgaa gcggacgtcg tgggacgacg cctgcccgat
     7141 atgatttccc tctcgtacgg caccaatctc accgagccga tctttaccca gatgctgctg
     7201 gatgaaacgg ctcaaggaca ttccttcaga accgatgatg gcatactcac gtcgatcacg
     7261 ggccgttcgt ttcccgtttc ctgcgtgttg gctcctatcg tgcgggacgg tcaggccggt
     7321 ggagcggtgc tggtctttcg ggacatttcg gagcgcaagc aggccgagga tgttcgtcgc
     7381 catacggaga gtttgttgcg gcaacatcag gccgcactgt ttggtctaac cagcaacagc
     7441 atcattcaaa gcggcgtgct cgagccggcc ctccgagaaa tcacccgggt gacagccgcg
     7501 accctcgggg tgcgccggtg cagcatctgg cttctgcgag acgaccatag cgccattatc
     7561 tgtaaagatc tccacgacgc gtccaacaac agccattcat gcgggatgga actcctcgcc
     7621 gcgcaattcc ccaagtattt ccgggagctc ctcacggaac gggtcataga cgcctcggac
     7681 gcgcggaccg atccccgcac gtccgaattc accgacacct acctgacccc gttagggatc
     7741 agctcgttgc tcgatatccc gattcgcttc aaagggaaac tggtaggagt gctgtgcaat
     7801 gaacacgtag gcacgccacg ctcctggatg ctcgaggaac aacaattcag ttatgccgtc
     7861 gcctcgttag tgtccttggc gctagaagcg gtcgagcggc tccacgccga aggggcgctg
     7921 cgcaaaagcg aagggcggac caggctgatt atcgacacgg cgctcagctc agtcatcagc
     7981 atcgacgagc agggacgcat tatcggctgg aacacgcagg cggagcagac attcgggtgg
     8041 acgcgccagg aagccatcgg tcgcttgatg gcagagacca ttattccggc ctctcagcga
     8101 gaggctcacc agagagggat aaggcagttc ctcaaaaccg gcgagggacc gatcctcaat
     8161 aaacgaatcg aaattagcgc gctgcgcaga gatggcacgg aatttccgat cgaactcgcg
     8221 atcaccccgc tccgtctgga aaatgcctat accttcacag ccttcgtcgt ggatatttcc
     8281 gagcggaaac aggcggagga agccctgcgc accagcgagg cccgcctcac aatgacggtg
     8341 caagggtctc acatcggcat ctgggattgg aatctcacca ccgatgcagt ctatttttcg
     8401 ccgcagtgga agagtcagct cggccacgac gataccacat tgcccaacgc attccaggag
     8461 tggcaatccc gcattcaccc ggaagaccgg gcgctggtcc atcagaccgt ccactcttgc
     8521 ctgaacggcg accgcgccca attcgaactc gagcatcgcc tgcggcatcg agatggatcc
     8581 taccgatgga ttttatcccg cggcaccctc atacgcgatg tctatggcgt ggccgcgcga
     8641 atggtcggca ttcatatcga tacgaccgat cggaaacgta ctgaggagga acttcgcgcg
     8701 gcaaaagaag ccgcagaggc ggccagcaag gcgaagagcg aattcctcgc caatatgagc
     8761 catgaaatcc gtacgccgat gaacggcgtg ctcggcacga ccgaactatt gctcaacagt
     8821 accctcaccg ataagcagcg ccatctcgcg tcgaccgtgc accggtcggg acgaacgctc
     8881 ctcgccatca ttaacgatat tctcgatttc tcaaaaatcg aagccggcaa nnnnnnnnnn
     8941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn cgctcctcgc catcattaac gatattctcg
     9061 atttctcaaa aatcgaagcc ggcaaactgg atctggaatg tgtcggattc gatctgtcgc
     9121 aacttctcga cgaatccctc gagctgttca tggaagccgc ccggcggaaa caccttcacc
     9181 tcactcaaca ggtcgatgaa cgggtcccgc gttatttgat gggggatccg gtccgactcc
     9241 gtcaaattct catgaatctg ttgagcaacg ccatgaagtt taccgaaacc ggcggggtgt
     9301 cgctgacggc cgactacatg agtggcactc ccactcatgc gcaactccgc atttcggtca
     9361 cggacaccgg catcggtatt ccgcccgcag ccaaattgcg aatttttgat gcctttgcgc
     9421 aagcggacgg ttcgaccacc cgacggtacg gtggaacagg tctcggtttg tcgatcgcca
     9481 aacaattggt gggcctcatg ggaggagcga ttacggtgga aagtgaaccg ggccgtggct
     9541 cgacattctc attcacggcc cgattcgaac tgcaaccgct tggcacggga acggacaacg
     9601 gcctgccatc ctatgagcga cttgctaagc cgcaccttac tctcgaaccg ccctatgggc
     9661 cgtcggagcc atacccgtca tcgcctggaa cggaggccaa gagaacggga caccgtgtgg
     9721 ccaggattct catagctgaa gatagcccgg tgaatcgtga agtcgccgtc ggcatgctgg
     9781 aaatcctcgg gtaccaggtc gagatggcgg aaaacggccg gcaggcattg gaattggtcg
     9841 ggcgcagtca gtttgacctc gtgctcatgg attgtcagat gcctgagatg gatgggttta
     9901 ccgcgacggg agaaattcgc cgacgtgaag cggcatccgg ccagcgaaga ctcaccatca
     9961 ttgccttgac cgccaatgcc atgcagggag accgggaaca atgtctcgcg gccggcatgg
    10021 atgactatct gaccaaaccc tacacgcagg tgcaattgca gaccgtcgtg cagaaatggt
    10081 tagacaagca agggactgat cgagcgctcg ccccagtctt cagctcaacg caggcggtat
    10141 ctggcgaatc agcccccgct gcagctgccc ccccaccaag cactccgagc atggatccta
    10201 aagctctcga cggcattcgg gccttgcaac ggccaaaccg gcctgatgtg ctggcgtccg
    10261 ttcttcgcaa gtatctcgat aactcacgag acagtgtaga tgccttacag gacgcgatac
    10321 gtgcgaacga tcccgctggc ttgcaagcag tggcgcatcg cctcaaatcg agcagcgctc
    10381 agcttggagc ccttgcggta gccgcccgct gtaaggaact ggaggcgctg ggcgctcaaa
    10441 aaaatctgat cgaagccgat cgtattttgg tcgaattaca atccgaatat gctgccgctt
    10501 gtgccgtctt tcgaaacgag atcgccaagg agaaatcatc atgaacccgc tcacctcggg
    10561 acggtcaccc tacgcattag tcaccgacga cgacatcatc atccgcatgt ttgcacggga
    10621 ggccctggaa caagcaggat gggaggtcga agaggctgag aacggactcg aagcctgcgc
    10681 ggcctttaag aagtgcccgc cggatgtcgt actgcttgat gtcatgatgc cggaaatgga
    10741 cgggtttcag acctgtgccg ccttacgaca gttaccaggc ggcgaacaca ccccgattct
    10801 gatcatgact ggtttggacg attttgaatc cattacaaaa gcctatgatg cgggcgcgac
    10861 ggattttatc gtgaagccct tgaacgccat gttgctgact caccgcatcc ggtatatggt
    10921 tcgagccaac caggtactcc aggaactccg agccagtcag gcgactctga cgcaggctcg
    10981 cgatgcagcg atggaagggg cccgcctcaa atctgaattc cttgcgacca tgagtcatga
    11041 aatccgcacg ccgatgaacg gcgtactcgg catgaccgac tggctgttgg aaaccgaact
    11101 gacggcggaa cagctggatt gcgcgcaaac gatccggtcc tcgggcgatt ccttgatggt
    11161 catcatcaac gacattctcg atttttccaa aatcgaatcc ggcaaactgt ctctcgaatt
    11221 gctcgacctt gatctgccga agtttgtcga tcgagtcctg gcgttattcg cagagcgagc
    11281 acaacgatag ggtctcctcc ttcattcgca gattgccgac gacgtcccgg ctgctttatg
    11341 cggagatccg acccgactcc aacaaatcct cagcaacctg ctggcaaacg ccatcaaatt
    11401 cagtgatcgt ggaacggtct ctcttaccgt cgatcttgac cagcggccgt ctgaacagcg
    11461 tctcgagttt cccgccacca gttatggcga actgtcatcc actgccagcc gaatcagtca
    11521 cgtgcgattc tccgtagcgg ataacggtat cggaattgcg cctaacgcgt ttgcgaagtt
    11581 gtttcagccc ttcgtccagg cagacggatc caccacgagg aagtatggag gaacgggatt
    11641 gggtctcgcg atttgcaagc aattggtgga actgatgggg ggacacatcg gagcggaaag
    11701 cgaacctgga gcagggtccg tcttccggtt tactgtccct cttcagcaac cactcgcgga
    11761 caacgaacga aacaaatcag ccgcctgaca gcaggcttcc tcttcccctt ctgtcgtctc
    11821 tgcgctcacg attatggaag agacgcctgt gtatcttttc agatacctcc tgtaagactt
    11881 ctctgataca cctacggcct cgacttcttg ggactgttag tcatcccatt gaaatcacta
    11941 ctgaaaagta atggcttaaa ctttgcttta cttcattgcg tacacatagt atacaaagcg
    12001 ggtcgaaagg ggtacctctc cagcgtcagc atgcaaaccc ttacccatcc cagctagtag
    12061 gcaaatccat acacccaagg atgacatctg tgcattgcct gacattcgac atcgaagaac
    12121 attttcaagt ctcacgattt gactcgccga ttcgccgacg acactgggga gccttcgaaa
    12181 gtcgggtgac agccaacacc tgcaaggtgc tggatcttct cgcgcgctat gacaccaaag
    12241 ccaccttttt tgttctggga tgggtcgccg agcgtcaccc cggtttgatc aagcagattg
    12301 ccgaatgcgg acatgaaatt gcgtctcacg gatatgggca tgaattagtc acagcccaaa
    12361 ccccggagtt gtttcgcgct gatgtgagac aggccaaaca gatcctggaa gacctgatag
    12421 gatctcccgt ccaaggatac cgcgcacccg gctttaccat tacgcgtgaa acgctgtggg
    12481 ccttaccaat cctggcagaa gaaggttaca cctacgactc cagcatcgtc cctatccggc
    12541 acgatcattg tgggcttcct ggatctgatc cctggcagca tctgaaacaa acctcgtcgg
    12601 gtcccatctg ggaggttccg ccatccacgg tcaatctcgg tggagtgcgg atacccattg
    12661 caggaggaag ttattttcgg ctgttgccgt tccccgctct gtgcggactg atgcggagga
    12721 tcgaacaaaa aggccggcct ctcgtcatgt attttcatcc gtgggaactc gatccgtatc
    12781 agccacatat ggaaggcccg ttcctttcca aaatgttcca ctatttgaat ctggacaaga
    12841 tggaatttcg catgtccacg gtcatgaaca gcttccggtt cggctccatt gctgaacaaa
    12901 tcgatctttc cccgatcttg cctatcgatc caaccgtctt cccttctacc ccagccgaaa
    12961 tcgcccaaga cgtcgtctga ccctcgtcac cgccaggctt tctcaaccag atagcatcgc
    13021 catctaggcg gttcacgagc ggccacgtgc tatgcaaaag taaggattgc actgcctcgg
    13081 caggttcagt acggtacgca cgtgagggac gagcctatac cagcctacaa gggagacgaa
    13141 gcatgcagaa gagacaggcg aatttatggg gctggtggct caggagggtc ggtctgaccg
    13201 tggcatgttt ctgcgtcgtg ctgctgccta ccacaggttt cggtcaatcc atcgaagaca
    13261 ccgtacagtt catcagcgac atggccaata cacacggctt cgtgcgaagt cttagttgcc
    13321 ggaatccgaa agccgccaaa ccaaccaagg tgaccgaaat ctatagtgtc attccaacag
    13381 gaaccagact cggcacgatc gagttgaacc acgggcacga cgacgtcaac accggcttta
    13441 ctcatttcaa tctgcaggac atcgagagca ttgcctacca ggggcaggac acgcgtgaga
    13501 ataacctggt gctgtatgcg gtccgcatat catgcaatag caatggcccc tgcattctga
    13561 aaaccagctt ttgcaccgga gcggtcacgg aagtgaaagg ccagtttcct gaggacacat
    13621 tgctctttcg ctccgcctca cacgctgagc gcatggccaa agccctctct cacttcctga
    13681 ccctcgtccg cacccagcaa cagaatcaac ccttctaatc agaaccgtca gcacccgggc
    13741 tgatcgtaca aggcagatcg gcccggtgct cacgtccagc gcctcactcg ataatcgtca
    13801 ccgtcatctc gacacgatca atcggattat cgcaagggcc cttgtctgca ggactcgggg
    13861 cacccgtttg gcacatgact ctcgggagtg ccacaatttt gtccgcgact ccgatccctt
    13921 tcaccacttc gccaaagatg gtgtatttcc ggtccaggaa acgcgattcc tccacgacga
    13981 taaaaaattg cgaccccgcg ctatcgggat cctgtgcccg cgccatcgag acaacgcctc
    14041 gcttgtgcgg cagatcgctg aactcagctt tgacgttgtg tccgggaccg ccttgaccat
    14101 aggcgtcttt tctcaacgag tccttggtgt ttgggtcccc cccctgaatc ataaacccag
    14161 gaatcacacg atgaaatatc gtcccgttat aaaatcctga cttcgcgagc ttgatgaaat
    14221 tttcgacatg tttaggcgca acgtccggca aaaacttgat ttcaatgtca ccaaccttgg
    14281 tcttgatgac cgctcgcaca ttactcgcat tgacggaatc gcctgccttg gcaggagcat
    14341 cagccgccag accggttgta gccatgccga tggccagaac caggctcatc actgccgcgc
    14401 acccaaatcg attgtgccat cgtgattgtg tcatcatgcc tccttcttgt cggttccttg
    14461 aagagctcat gtcgttaatt gtgtcagcgc ttcccgcgcg gccatctgct ctgcctcttt
    14521 cttgctgtgc ccgcatccga ctccccgcat cacgccctga attgtcagtt ggacctcaaa
    14581 caccttctca tggtccgggc cggattctcg aaccgtcgca tactgcggca aactttcaaa
    14641 ccgcttctga caaagttcct gtagctgcgt cttgtaatcg tccattcccg gccgggcccg
    14701 ttctgcgcga gccgccagca actcctcttc cagcacacgt aaggtaaagg tccggctcgc
    14761 ctcgaggccg ccatccaggt aaacggcggc gatcaacgcc tcgagggcat cggccagcaa
    14821 cgagtgtttt tcacggcctt tcgaaagctc ctcgcccttt cccaaccgca acagacggcc
    14881 gagcttcatc cgacgggcgg ccttggccag ggacgcctca ctgaccaaat gcgccttcag
    14941 tttggacagc ccgccttcgt tgctgccggg gaattctgcg gcgagatact cgctcatgac
    15001 taacgacagg accgcgtcgc cgagaaattc caagcgctcg ttttgagtgc ggtctttggt
    15061 acgtcgctcg ttcgagtagg atttatgggt cagggcttct tccagcagac gcggctgacg
    15121 aaagcggtag cccaacaggc gctggaccgc ctcgattgac gttgccgacg tcataccacc
    15181 tgactcgtgc tctgaggagg attattggtc acaccggcga aaaagcaggc aggcgttgac
    15241 cccgccgaag ccgaatgaat tcgaaaggac cacctgagtc ttggtcgcac gagccttatt
    15301 cggaacataa tccaagtcgc aggcgggatc aggatgatca aggttgatcg tgggaggcag
    15361 aataccatgg tgcaacgcca gaatactgaa tacggcctcg atcccaccag cggcacccag
    15421 gagatggccc gtcatcgatt tcgtcgaact gaccggaatc ttataggcct gctccccaaa
    15481 cacgtgcttg atcgccttgg tttcgatggc atcggccatc gtcgaagtgc cgtgggcgtt
    15541 gatatagccg atgtccgtct tcgccacacc agcgtctttg atcgccattt ccatgcaacg
    15601 caccgcaccc tcaccttctt cgggcggcgc cgtaatatgg taggcatcac tattcatggc
    15661 atacccgatg acttcggcat agatgcgtgc accgcgcgcg cgggcgtgct ccaattcttc
    15721 gagcaccacc acgccggccc cttctcccaa cacgaatccg tcacgatcct tatcgaaagg
    15781 ccgactggct ttcgccggtt cggtattcct gaacgaaagg gccttagccg acgcaaatcc
    15841 ggcaacaccc agcggggtaa ttgccgcttc cgcaccaccg gcaatcatga catccgcatc
    15901 gtcccgcttg atgaggcgat aggcgtcgcc gatgcaatgg ttccccgttg cgcaggccgt
    15961 gaccgcgcag gaattcggac cttttgcgcc gactcgaatc gccacctggc cagaggccag
    16021 gttgatgatc gtcatcggaa taaaaaatgg cgagactcga ccggggccct tttccttcag
    16081 cacatcatgg taatgttcga tcgatcccag cccgccgatg ccagacccaa tatagactcc
    16141 aaccctcgtc gcctcttcag ccgagacttt caggccggca tcgtccactg ccagctgact
    16201 cgcccccacc gcatagtgga tgaaggtgtc catcttcttg atttcttttt tctcgatgaa
    16261 ctgcgccggg tcgaaatctt tcacctctgc ggcaatctgc gcatcgtacc cactcggatc
    16321 gaatcgcgtg attcggccga cgcctgactc gccggcgcac agcgccttcc aggtcttgtc
    16381 tacgccggtg ccgagaggcg tcaccagtcc aagaccggtc actaccacac gtctgacggg
    16441 tcgatcgtgc atactaccgt ccgttacgct ttctctttga tataatccag cgctttgcca
    16501 acggtgagga tcttttctgc atcctcatcg ggaatttcaa tctcgaactc ttcttcgagg
    16561 gccatcacca gctcaaccgt atcgagcgaa tccgcgccca aatcttcaac gaaatgcgcc
    16621 tccagcgtca cttcttcttc ctcgacccct aactgctcgg caataatttt cttcacccgt
    16681 tcatctactg ttgccatgga cttgcccacc tccttcctat cttatctcat ccgccacatt
    16741 ttttgccgga acatccggtt cgaccgaacc gatcgagaca caggcccgac tcacttatac
    16801 catgagcatg ccgccgttca cgtgcaacac ctgccccgtg atgtacgacg ctgcatccga
    16861 caccaaaaac cgaaccgccg cggcaatatc ggaaggaagc cccaatcgtc ccagggggat
    16921 ctgtttctgc aaggcttctt tcacctccgg cggcaacccc tgcgtcatag ccgtatcgat
    16981 aaagcccggc gccacggcgt tgaccgtcac ggcgcgactg gcatattcac gcgcggccgt
    17041 ttttgtaaac ccgatgaccg ctgcttttga cgccgaatag ttcgcctgcc ccacgtttcc
    17101 catcgccccg acgatcgagg cgatattgac gatacggcca aaccgttgct tcgtcatggg
    17161 gagcaacacc gctttggtgc aatggaatgt cccgttcaaa ttgacctgca ggaccagatt
    17221 ccagtcttct tccttcatcc gaagcagcaa cccgtcgcgc gtaatcccgg cgttgttcac
    17281 caggatatcg atccgacccc attcctgcat gacctgatcg gccatggcct tcgcatcatt
    17341 ccagtcggac acattcactt tgacactgag agcccgtcgc cccagtttct gaatcgccgc
    17401 aacggcatcc tgcgagcgcg ccgggtcgag gtctgccacg gcgatatccg cgccatcctc
    17461 agccaaccct tccgcaatcg cacgcccgat tccctgggcc ccgccggtga caatcgctac
    17521 ttttccctgt aatgacatca gtctactccc acgcaatctc gaagctgctt atggctgcct
    17581 gtttacgccc acagtggtga gggctgcgtc caatgacttt tgatcatgga cattggcggt
    17641 gactgcaccc ggaagtatcc gcttgaccaa gcccgtcaag accgtcccgg gcccgatttc
    17701 aagaaaggtc gtcacaccca tcttggccat ggtctgtacc gactcttccc atcgcacgga
    17761 cgagggcaac tgtcgcacca acgatgcccg gatgtcttct gatcgctgca gggccaccgc
    17821 ctcggcatta ttgatcaatg gcaccgtcaa atcccgccac gcgactccgc cgaattccgc
    17881 ggccagccgg tctgcagccc cctgcatcaa gggtgtgtga accggtacac tcaccggaag
    17941 cggaatcgcc ttcttgcatc ccttcgattt ggcaatgtcg atcgctcgtt cgaccgcaac
    18001 cttctcgccc gcaatgacca cctggccggg agaattgaaa ttcgccgcgg cgaccacacc
    18061 gacagaggag gcctcctgac agacggcttt caccacttcc gcagaaagac cgagcaatgc
    18121 ggccaccagc cctgtccccg gcggaacagc ttcggccata taccgcccac gcttttgcac
    18181 cagagccacc gcatctcgaa acgatagccc gccggctgca aagactgctg aatattcccc
    18241 gagactatgc ccggcaaccg ccagcggact cagtccggcc ggttccaagg ccttcagcgc
    18301 tgctgcactg ctgacgagca aggccggttg cgtgtgttct gtgagattga gccgttcaac
    18361 cggcccctca aaacagagct gagccgcatc gtagccgagg atggtggagg cctcttcata
    18421 caccgccctc accgccggga acgcatcata caacccgcgt cccatgccta ctgattgcga
    18481 cccctgtccg gggaacaaaa atccgatggc tgaagctgtc ataaccgcgt aaggtatcgt
    18541 agaaaccagg ctcaatgtca acggaaaaag ccggacacat tcggcaccgc cggacttcac
    18601 atccggctac cgaccagtgg ccgcaccttc accagcgaat cagcgtcgac gcccaggtca
    18661 gccccgcgcc gaaagctccg aacatcacca attgtccatc cttgacccgt ccgtcccgca
    18721 cggcttcgtc cagggcgatc gggatggagg ctgccgacgt gttgccgtat cgatccatat
    18781 tcaagacgac tttttcgagc ggaagaccga gacgatcggc caccgctttg ataatgcgca
    18841 ggttcgcctg atgaggaata tacagatcaa gatcatcgac tgacagctgg tgcgctgcga
    18901 gcgtttcgcg tgcgacttcc tccagagtcc gtactgcgac cttgaacgtt tcgttgccct
    18961 tcatcttaat gtactgcgac cgctcgccca ccatcgcttc agaaggagga atccgggttc
    19021 cgcccccggg caccacgatt agatcggaca aactgccgtc cgaatgcagg tggctggaga
    19081 ggatgccacg ttctccctcg gcagcgctca ccaccgcagc gccggcgcca tcgccgaata
    19141 aaatacaggt attgcgatcg gtccaatccg taatcgtgga catcacttcc gagcccacga
    19201 cgaggacatg gcgcatcccc gttcggacat aggcatcggc gacgcccaac gcatagacga
    19261 acccgcagca agcggccgag atgtcgcagg ctgccgctcg cgtcgcaccc aggcggtgct
    19321 gaagcagaca ggcagtcgac ggcaacggca tgtcgcccgt gcaggtggcc aggagaatca
    19381 ggtcgagatc gctcccggaa agtccggcag cttttaatgc gcgttccgcg gcgatcaacg
    19441 ctaaatctga acaggcctgt cccggagccg cgatacgccg ttcccggatt ccggtgcgct
    19501 cgcgaatcca ttcatccgag gtcgccacca gctgctccag gtcactattg gtcatcaccc
    19561 gctcgggcgc ataagaccca gttcctgtga tccgcccccg tatcacgcct gtttgtcctc
    19621 cagccgctcg tcctgatgcc gtctcaagct ctcctcgatg tcgcgttgaa tcagctcatc
    19681 taaccgggtt tcggccaagc ccttcgctcg tcgaatggca tttttgatgg ccttggcgga
    19741 tgagcggcca tggcagatca tggtcgtccc attcaccccc agcaacggcg cgccgccgaa
    19801 ttccgcatag tcgatttttc gcttcaaatt cagcaacggc tttgcaatca acggataagc
    19861 caaccgcccg agccaggaac cggagagttc cttcatcaac aacttcttga tgacgtccgc
    19921 gacgccttcc gaaatcttga gggccacatt gccgataaac ccgtcgcata ccaccacatc
    19981 ggcgcttccg ctgtagactt cgcgtccctc gatattcccg ataaaattca atgggctggt
    20041 tttcaacagc ttgaacgctt ctttcgtaac ttcgttcccc ttgctgtctt cttcgccgat
    20101 gctcaacagt cctacgcgcg gattgggttt ggcatagaca tgcctggcga attcattgcc
    20161 catcaaggcg aattgctcca gatgttgcgc cgaacaatcg acattggccc ccacatcaag
    20221 catgatcgca cttcccgtca atgtcggtaa catcgtggca atcgccggcc gctcgacacc
    20281 tttgatcaat cccaacacga agaatgaggc caccatgctc gcgccggtat tgcctggact
    20341 gaccacggca tcggcttcac cggatttgac cagctccgtc gccacccaaa tggacgagtc
    20401 ccgcttcttc ctggccacag cggcaggtga ctcgtgcatc tccaccactt gcggcgcgtg
    20461 ccgaatggta atccgcgtat cgttacagtt gagtttgcgg catgcggcgg tcagctcgtc
    20521 ttccttgccg accaaaatga tgccgacacc cagttcctgc gcggcttgca tcgcgccttc
    20581 aatgaccggg gccggtccgt ggtctccgcc catcgcatcg acggcaatct tcatgtgcgg
    20641 ttagcggtcc acggatagag aagtgaagag tcgtgcagag acgccctgcc ggctaggacc
    20701 tgaacggcct cacgcatgac atagcgtcgg atcgtgatca cggtgggcaa ttgtacccga
    20761 atcacgtcga aaaaataaaa cgcgactagg attcctcgac gacgatgacg gccttgcctt
    20821 tgtacgttcc gcaattcatg cacgtatagt gcgggagctt caattcgtgg cactgcgggc
    20881 agagcgaaaa tcctggaggc accagccggg tcttcgctgt tcgccgcatg tcgcgacggg
    20941 atcgtgaatg tttgtgtttt ggatttggca tgacgactcc ttcaacgggc acaacacccg
    21001 gttaacagac tatgcgtttt caccttttgg cccacgccct cgcagcaccc gaaacggact
    21061 cggcacttgc gccggagggc agtcgcatcg gcgctcatta aggttctgtc cgcactgggg
    21121 acaaagtccc gggcaatcct cgcgacatat cggctgcatc ggagcggcca gaattacctg
    21181 ttcgcgcagc atcgggacga gatcaagatg atcgccctga taccagtaca gttcatcctc
    21241 ttcatccgcc tcttcttccg gttcaaccgg ttgagcaccg cgtctcgtat tccgtcttcc
    21301 ctgttccgcc ggagcagatt tcgcagccac actcgcctgc ggaagatatt ccgcatagag
    21361 agagacgagg agcggatcgg catattccga aagacaacgc acgcattgac ggatcgcggt
    21421 gccttccaac gtgccggtga ccgagatccg tccttcttgc tgcgagagct caagctgaat
    21481 ggccagcggg ccgccaaact tatcttccgg ctcatccaac cccagctgag gccccgaagc
    21541 cgagcatgac aggggcagcc cttccggacc aatatcgaca atcgctgggt tgagcatatc
    21601 catgggcacc gtcatgacga gacgatcctc ccccgtatcg atcaggagac aggctgccgg
    21661 gccacgtgac tcaacactca ccaaaaccta tccctgccct atcgctcttc ggcaaaactc
    21721 accagggcga tctggcgagc ccgcttcact gcgaccgtca acacccgctg atgctgcaag
    21781 caattgccgg aaatgcgacg gggaacgata cgtccacgct cggtcaaaaa attccgcaac
    21841 aggccaacat ccttgaaatc aatcggtgcc ttatccacac aaaaccggca aggcttgcgg
    21901 cgttgaaaaa accggcctcc gccccctccg ctgtttccac gatctcctcg ttccatgatc
    21961 gcctccgtct cctagaactg ttcgtcttcg tatgaaggtg gttcgtcgtg caggccgccg
    22021 ctgtctgctc cggctccggc ttcgccccgc tttggcaaaa aggtcacgcc ttgcgccacg
    22081 acttcgtgct tgctacgttt ctggccgtct tctgtctccc agcggcgctg ttgaagccgc
    22141 ccatcgataa tcaccccgtt gcctttgctg aggtactgcc cgcagtgttc cgcttgcttg
    22201 ccgaacacga cgatatcgat gaagcagact tcttccttga gttcatcacc ctgcttgaag
    22261 cgccggctcg tcgccaagcc gaagctcgcg accggcgttc cgctgggtgt gtaccgcagt
    22321 tccggattcc gagtcagatt tccgaccaga atgactttat tgaaccccgc caacggtcgc
    22381 tccttgtgcg gctggtgctg ccacaggtgc gcccctgggc ggagcaggct cctgctccaa
    22441 tttcaccgtg aggaacttga tgatcgaatc ctcaaggcga taggcgcgct ccaggtcggc
    22501 gatcgtggta ccgggaccct gaaaataaaa atagacgtac gtgcccttac gctcacgctt
    22561 gatttcatac gcgagcttct tgcggcccca gttctcggct cgcacaaggg tggcgccgtt
    22621 cttggtgacg atacccttca ttttttcaat cagcgtcgtc gtttcttcgt cgcttaaagt
    22681 cggacgaata atgaacaggg actcgtagag ctccatgcag attcctcctg gacattggcc
    22741 cccatcatag acgggagcga ggtgtaggca tgccggatca gccgacatga gccgtggaaa
    22801 gtaccatagg atttttagac ctgtcaacct tatcgctctg ccgcggcacc tcctggccga
    22861 tctttccggc gacgaaaccg tgcggtatcg acgtcagggc tctccttccg gcaccatcca
    22921 gcccgtcacc ggcgagatat atggtggatc ggacatcaga ccgaccactt ttgaagccac
    22981 gcgtcccaga cggcggtgca cgccgtacgt caccgaaaac cctgccccgg tgtcgtattc
    23041 gcgacatgcc tccagcgcat caaccatcgc ctgacggtcg agacgcctgc cggcctgctt
    23101 gactgattcg gccagcaacg aaacggcgcc gtgagcgatg cgtgcaaagc cgatgctcga
    23161 tagagacggc tgctcgctca acgcccgcaa ataggtcacc tctcgctccg taggagggtc
    23221 aatcggggtc acgaggaata tccggggaag aagagacgac ggaacagccc gagcccgtgg
    23281 ccccaccatg ccggttgcac tcaatacaat cggcgacatt ccccggcgac ccagctcatg
    23341 tgcgatcgag acaagatcct ctccatctcc cagaaatacc acggcatcga ttgcctgctg
    23401 ttccaattgt gccactaggg ccagcactgc cagacgaccg gtcgagtact cgtaattcat
    23461 cgcgagattc aacgcatgat gccgaatctg ttccagggca ccacgcaacg cctcactatt
    23521 gctgtcccca ttcctgtgca cgagtgccag acgaggctgt gctgtccccg tgagaggcat
    23581 cgtcctggag gcaaaaaaat ccatcaacga ccggaattga aggtcgaacc caggcaaggc
    23641 atagaatatg gaagggtctg gtggatccga gagctgaggg gattgagtca gcggaaaaat
    23701 cgaggggatc tgatcctgct cgaaacgttc acggccccct cctgccggct caaagctccc
    23761 cacgagggcg aaaacctgat gaatctcgat caagcgggag acagcctgcg ccgtctgtgc
    23821 aggatctccg cgagaatctt ctacaatgag ctcgatgtgc cggccgtaga cgccgccctg
    23881 ctcgttcacg cgccgtagtg cgcccctcaa ggtcgcggcc acatcctgcc cgatctgtgc
    23941 gagtggccca gtcaagggaa gcgccgctcc gattgtaaca acctcggcgc tcacgccggg
    24001 atcggtatcg gcctcttccc cgagccgcgt cagatacgcg atcagcttcg ccacctgatc
    24061 ggaggtcagc tgataccgcg gcatactcgg atgtaacgca tggccggaag cgtcgatgcc
    24121 ttgagtaatg gccttcccca gcgcctcatc ggtgtatccg gcccgaggtc gtcccgcgct
    24181 ggttccctcg cgcgcccgcc tgagcaccga tacggtgagt ggcggcactc gcaacccacc
    24241 ttcctgtgat ccttccccac ggtgaccatg gcatcccgcg caccgaaaca gggccggcgg
    24301 aacccctccc tcaaccccct gcaaatttac ggcaaccggg tccgcgattc cggcttttcc
    24361 ataatgatac aggttgcggc cttggcgctc ctccggcgtg agggggtcga tccaagctgc
    24421 agtggagggc tgcgccaggc aactcaccat gataagcagg ccgacggtga cccaagtcct
    24481 gctcacgacg gggcatcgat gtaccatggt gcgatgacct attgagagat gccggaaggc
    24541 gtcaaggccg gcggacccgc tgtggcgtca agcccgtcca tcaccatcgg aacagaggcc
    24601 tcgccataca ggcgcgtcca tatcccggcc gcctcattcc caatgaccac gatggctgga
    24661 tgctctgcct tgtttgatgc agagacctgc agggatgcca gaatgcgggc cacatcggca
    24721 ggtgcgccgg tgagaaagta ccatcccttc cctgcgccaa actgggccgc atacgcttta
    24781 agccgtgtcg gccggtcgtg aacggggtcg accgtcacag acaggagggt gacaggacgt
    24841 tccgcggctt ggaggcggtg gtacacccca ctgagcaagc cggtggctgc gggacaactc
    24901 gttttacagg tcgtatagat gaagttgatg accacggttt tgcccttcac catatcgccg
    24961 taaaaacgat gtgggacacc gtcctggtca atcacctcga catcggggat ggagggcggg
    25021 gtgacaccgg accaggccgg cgccgcatga gcgccacaca accacaagag catcgcggct
    25081 ggaacgaagc ggagcatcat agatcagacg ccctcatggc ttgagcgcct gctccgaaga
    25141 gcctgtggac acagacatcg gcggcccgac ggtgagcaga acaggcggag catctgagaa
    25201 gcggaggtgg cgggatggcg attgcaccaa cagccggtat tcccccgcat gcggaaaaga
    25261 ctgggtgatc acataccggc cggctcgttc ttcttgcgcc catcgccgct gttgccacgt
    25321 gccgggcggc tcgaagatca acacttgcac gtcatgaagc cccacgatcg gctcctgagt
    25381 ggtggcatcc agcaagtcaa acgacaagga agcgggaacg tgcgccgaca cgagatcact
    25441 ttcgaaccgg gcttgtatgc gtactggtcg agggcctgga gccgtcgctg tggatgccgg
    25501 tgactcctga accgtcactt gaaaacagtg ggacattcga ggctgatcaa gcagcagggg
    25561 aacgtcgaat cggccagggt gcggaagggt cacagtcgct tgatagacac cgggggccac
    25621 ttctctcaag cttcgatcga gcacgagaac gcctcgcggc atccgacgat aattcgagaa
    25681 ggttcccgac ggagccatca tgccttcctg ataataatgg agcgtcgcat ccggtgcatt
    25741 ggcaatcatc acggcgttgc cttcgggcgt cggaacaatc atgggcgcaa caccaagttc
    25801 ctgtggcgcg gcactcggcg cttgcctccc ggcttgcaca tcgagcggga ccagtttccc
    25861 atttcgcgcc tcgcgcaggt caaggagcgt aaatttttct gactcgatgc cacgcacata
    25921 ggcgtatcgc tgtgtgaaca cgatttgatc gggatctttg accacgtgtg cggtagccgt
    25981 tacggtactc gtggcggtat cgatgacaga caggctgctc tcaacctgat tgaccgcaaa
    26041 gacaaaccgg ccctgaggtt cggtggccaa agcaaccacg cccgcggcca tgggaatccg
    26101 gcccacgagg cgatgcgtcg acggatcgat cgctacaatg tctccgccgt tgacaccacc
    26161 gacatacaaa cggcgggctg cactgctgta cgtcaccgcg actggtgttt tgccaaccgg
    26221 caccgacacc accggcgcca tggcctgcgt gtcgatcaca gacacgctat cgctctggct
    26281 gttcgtcaca tagatgaatc gaccgtcggg aatcgcggcc aatgtatgca gacctcgtcc
    26341 caccgtgacg gtcttgagcc gtctgtgtcc ttctccatca agcaccgcca cctgacccgt
    26401 tccgtccagc cccacccaga gccggcggct gtcaggctgc cagagaattc gtcccgggcg
    26461 ggatcccttg tcgagcgcaa tagtctggat gagcttccgt gttcgagtct cgatcaccgc
    26521 cacggcgtct tcgcccggaa tcgtgacata gagataactc tgatccgggc tgaggaccca
    26581 atccgctcca ttgccaggca gcgtcacgag gctttccagc ttggtcgcgc caaactccac
    26641 ctgcggatcg atcaccgata ccgtcttgtc gtggttcatc gtgacaatca cgtatcgatt
    26701 cagatcgact tcggcacggg ctcccaatcg tcctccggcc agccggcgga tcttctcgac
    26761 gcagctgtgt tcatccgccg ccatttccga aggccgaccc accatccacc ccttcggcct
    26821 tattcccacc actggagacc cgcttttcgc atccatcagc gcgaccttca ccgtagctgt
    26881 ctggccggca gtcagttctg cccctgtctc ggaagggcca tcctgaggaa ccacggtcag
    26941 ctcgatggca agcccattct gctcaaaccg ttgcacagga tgggatggcg cagtctctcc
    27001 ggccccgact atcgccggag cggcaaccag caggaaagcc gggagacttc ccctagcccc
    27061 gacaaggata ttgcgcatgg cttgtctcat ggctgcacaa tcggcgcctc gttcgccgcg
    27121 tgaactttgc acaggtcggc cgaggccaca ccgttcgtct cgtacccaaa caggttgccg
    27181 gcccaagccc aagccggttg ataccagcgt aatccgggat tctcctcaac ccggaagatc
    27241 ccccacaatc caccgccgaa catgaacccc tcttgcgtgc gatagagata gtcgcccgga
    27301 accttgcagt ccccgccggc cgttgtgagg atattgacgt cgcggcccgg accaatcccg
    27361 ccggctgatc cgacccgcgt cagaccatcc tgattccagc ccatggcttt ggacgcatcg
    27421 atccagggac tcggcaccca gtcatggccg aacaccgtga acgcgtgctg tcgtggatgc
    27481 cctcccggat gcaccacccg gaaccgcacc ggctctcctg ccttcgcggt aaagagcggc
    27541 gtttcgggat cacaatattt cttgttcgca aaatccgcct cgcagcggaa gtgcggcacc
    27601 gtcgagctca agacgtttga ccaatcgaac tgactcatcg tctccggttc gtcggctgcg
    27661 ctggccccta atcgcgccca gagcggctcc gtgcggtaat tgaagccttt ctgccccgag
    27721 tcttcggagt cgtcgccatt ccgcaaattg ggaacaggct ggccatactg ctggacgctc
    27781 aggttatcct gatagagcaa caccatttct ttgaatcgat acaacttccc ggagtccagc
    27841 ttgggctccg cggggcagat ctgccgtttg agatgcctgc cctgccggcc cgaggccgat
    27901 tccggcttcc aataggtcac caccgcttcg gcgttgccgg tcgacggcac agtgtcccag
    27961 cgtgaacatt gcggttcgat gagtaatgcg ccgatcgcgc catgtgacgc atgcttgatg
    28021 acatccccca tatcctgcaa gccaatggcg ccaaactcat ggggaatgcc gacgatgcga
    28081 gtccctttct tgttgggcac aatgtcgcca gcgtaccaga ggtaggtctt gctgacacct
    28141 ggcgcgacgg tggagtcgtc attgagtccg acatgcgcgc cgtcactctt tagcaggtta
    28201 tagtccacca actgtggatg cagtccaacc cggctcgacg aacgcacctg attaaacgag
    28261 aacccaggga cgatcggtgg aaccatgttg taactccagg tctccggata gtcgggacca
    28321 tcctgcatgg cggcagggag atggttggtc agggtgacac ggatacaatc ccctgccctg
    28381 gcacgaagaa tgagcggctc cggccgcttg cttcctgacc gcagcatggc tttctcacta
    28441 gcgtctacaa agataattgc attggggtcc gcaataccga aatgctcgtt gtagaccaac
    28501 ttcccactcg gcaacaggtc cttggccagc caggcttcca cctcatagga acgagtcaac
    28561 tgagcctgcc cgcttttttg gcagaaggcc tccagcgcat cgctctgtgc caggttctga
    28621 ccggcttcat ttcccgcgtc atcatctgag acatccagtg attcgcgatc caacagctca
    28681 tccaggtttt gcatgaaggc tgacgccagg acatcgtgcg tcttctccgc attgcccggc
    28741 aaacgaacca gccctggctc gtcctcggta cgggaataga cacgcatcaa tccccactga
    28801 ccatcccaca aattatccgt ggcggctgag gagtagagat ggtcgatcga tgtgtgttcg
    28861 cctgctccgc cgagcgattt gtgtccgttg cttcgcccga acggcataaa gtccaccacg
    28921 cgatcgttga attcaaaatg ctcggaaatc ccgatcgtct gcgcatttac gtagccggtg
    28981 tttggactat ccggctgggc cagccatttg gagccatgca tggtgaacac atgctgttcc
    29041 tcctgggcgc cctgaatcag ccgaatctgg acatgatcgc cttcatacgc ccgcaggagc
    29101 ggtgtcgccg gatcacctgg catacgtcct tttccgctag gctcggtaaa cagacgctcg
    29161 tcgacagatt tctggtcttt gtgaaccgtt gaactgaacg catgcgccag atcgcctttc
    29221 tcctgatcga cgggcaattg tttgaactga tggccgtctt tgtcctgtgt gccgatgcgc
    29281 agcggaatcg gttcgttccg ataattgatc agctgggaac cggggtcttt cgtggagatg
    29341 ccctccggca caggaatacg gccggggaga ataggcgtcc gtaaaccacc ttcgatttga
    29401 ctcggtgggt tcaccggttg attgtctttg tcgtacacaa tcgcaaaatc ggcgaaggcc
    29461 agattgaatt cccgcccggt ccgttcggca tcgatgctgc ccttcgaatc gagcgcgtca
    29521 ctgcaaagaa tcccgtcctt gtccggtgta atgcaggcct tgccctgagt gcgtacgacc
    29581 acgttcgcgg cataggaggt cggtccaccg tcattgcgcc cgttcaccgc ttcaggcacc
    29641 cccttggaat ccgtcccccc catcagttgt ccatccggga aataccactt ggaatttctc
    29701 ggctcgacca ccagcgcggc ataaaacccg tggtgctgat gcgaactcgg gccaaaatgg
    29761 tcgtgggtga acaccgtgcg catcgtgcga tctttagtgc ccttgtcgcc aggctttccg
    29821 ttcagcaccg gatccgccca ccatcgttgc gtggtggttt gcgcgccaca ccagggatga
    29881 ccgacgggat cgtgatcatc tgccgcctgt cccgtgatat cgctacacaa cccgcgcgga
    29941 tcccctgcca tggcgccgtt ctcggtcgcg ccaagttgtc ccttccgaag gaagagacgg
    30001 tgggtgcgag gcttgagccg ttgcgcggga ttcgtcttat tgtaggccag aattcgctcc
    30061 cgcacctcat cggcggctaa cgtgccatct tcatagttcc atccattgcc tgatccatcc
    30121 gatgaggtga cgtcgaattt caccagatgg atgtgctgac cgatcgtatc ggtcggcgta
    30181 tagacttgaa aatcatccag gttgagattg ctcggaatca ggttggtcgc gtgaaagacc
    30241 acgcactccc ctgactgcgc ccggaagaac agcggctccg tggggcgagt cccgtccagc
    30301 gtctctttca cgtcttgttc caagatggga aaacgggctt gcggatcatg ccagcccgat
    30361 ttgttgaccg tcatattcat ctggatatag acggcgcgat actcgcgagt cttcacgtca
    30421 tgcacgccac ccttctcatc gatgaattgc ttgggacagg ggtttgaaaa cggtgcaccg
    30481 gattccccct ctccgcgttt ggcctccgca atgttcccac ctccgttcac atggaacaac
    30541 acgcgcgtcc cgtgagggtc gtcgcagagt ccgttagaga gacaggtgac atacccaggc
    30601 gcttcccagt tatacggact gtaggtccac cccggatctc ccgggcgaac ggcagaagca
    30661 ccgtttacct gagacattcc agcatgaaac ttcattgccg ccttttcgtc tgtcgtgccg
    30721 gcggtcgcct tcacatccag tttcgccgtg accaattcgc gcgccaaccc gactaaatct
    30781 ttgtcggtat tctgggtacc tacacgcgcg gcaatctgtg ccgactgctg ccgcccctta
    30841 tcaaacaagt catggttcat cggcggagcc tgcttcatct ccttcggccc ctgcgcatcc
    30901 agcgcgtcgt gcaccgtccc ccctgccacc acgtgtcggc gaagcgtgcc ggcatcgtcc
    30961 ccgccttcca gatcgagcgg cggctgcgga ggtcgatggc cgatttctcc ggcgatatag
    31021 aacggatagc ccttgaacgt cggagtcggc atagggggca gcggggtacg aggcaatggc
    31081 acaatggccg gtgtgggagt acccccggca atatcgtggt ccttcaaccg gcggtcgtag
    31141 cctccatttt caaacacatc gtgcgtccgc cagagttccc acatcccctg cgcaaaatgg
    31201 ggatagaggt gacaatggaa aatggaatcg cccggtccga gattgcggtt gccggagccg
    31261 ccgtaatgca cctcgtacga aaaggtcgtg cctggcgaga tcgtctgtga gtcgagataa
    31321 tgggagaggg gatcgtgctt atcctcgacc cattgatgcg catgcaaatg gaacacatgg
    31381 gtctccttgg gacccgcatg catgttccgg aatcggacgg gatcgccgag ataggaatga
    31441 tgcacattgg agggatcgtc gggataccgc gcctgcatta cgaatcgtcc gttcccgtcc
    31501 ttcttgtaac tgccgccttt cccccgctca tacccgacca ccatcgccgg atcgccattg
    31561 acccaggagg tgaggaagaa ttcttcgagt ttgcattcca cacaatctcg cgccgggccg
    31621 agcttgttgc ggttggccac aaccatcgac cctacgccag aggccccgta attgatgccc
    31681 atgccgtcgc gcagtgaact cagcggactt ccttcctccc ggatttcatc gaacgcctgg
    31741 acggcggtga tctcatcatg gaaaatcacg gtaaattccc ggtacggttt tccacaagca
    31801 ttaccttcgc ccattttctc gcagccgttt tcccggtcga tatcgatcac ggcattcagg
    31861 tccgaatgga caagctcgca ctgccggttg tctcgcggat cacacttgag catattcaaa
    31921 atcgggtcac cggcatgtgg ctcgttcttg tacgtagcct cataatcaat gaccggctga
    31981 ccgaatttcg tctcttgctt atagctggcg gctttcaagt ccttctcagt cacctgggag
    32041 cgataccact ttgcgccacg aggctgtaca ttgatcgccc cgaacaggcc taatccgact
    32101 tgcccgccgt cgccctcgcc gcccgcaggt gcccccatgg aatagagaaa aaacgtccct
    32161 tcctttttgg cgtaccacct gtacgttctg gtttcaccgg gtgccgccag cgcgcacaga
    32221 tctttgccaa aatcacttcg gttggatgaa caccggccat cggtcttgtt cccgctttgg
    32281 tcatgccatc cattgcgacc gacattcgcg ccctgagagt cgatggaatc caccaaactc
    32341 aatccgttca catgcatgga ggcatgtctg gtcgacggtt catcgctgtc actaacggcg
    32401 gtcacgcgct tgtccggccg ggagagccgc ttttccggat caagcatgac ttcctggccg
    32461 ttcgtctcgg gagaaagcag gttcgtgaag gtcacctcca gacagtctcc ttcattggcc
    32521 cgaagcacca gcgggcgagg ccgcttatcg gaacgcaatt tcacattccc agccaagccg
    32581 agatcggcag gcccatgctg aagggtaatt gccttctctt gttcgtccga ccgattgtcc
    32641 aggtcgccat tgagaaggtc ttcctcatcg gcatgcacaa catcccgtct cagcgcgaac
    32701 atgatgccgg ccggattaaa tgctccgaac cggttgtagt aatacacctg gtccaaggcc
    32761 acgacttcag ccgtgatagt cctctcacag gccggtttca ccacctgctg ggattccggc
    32821 attttcggct tggcgcaccc ccaccagagc agggacagac tgacaatcgc tgcggttttg
    32881 gccactacgc tgaacgtaca tacgtgcggt cttgatggag cgccttgaac atcttcgcca
    32941 ggcatgtccg cactcaattg ggtagacgct ggaacaaatt catcatctcg catggtcaag
    33001 gtctccactg ggctcattcg tgacaatcac accttattgc gtgcaggaaa acgtcggggt
    33061 tgcgacgccc ggccaaggtg tcaggcgagg aatattgggc aacccgctat cgggaagcgc
    33121 ccatccgttg gcgagaaatg ccagacattg gaaattcagg gctggttgag ccccgccttg
    33181 cacaccagtt ggttccggga aaatatattc gccgaccggt gcgacataga tgccggcggt
    33241 cagaccatgg gcagccttgg gtgcgctcgg gacatcgctg ccgtccgata gcggcgcggg
    33301 gtcgtcaatg cgcaccatca gctcgcgcgt ggctcccttc aaatttccgt tgaaatcaaa
    33361 gagcgtagcg gcggtcaatg gtggaacgta gcggaagcga ccaaagacgg cttgatcctt
    33421 ttccgtgctg tgaagtaacc ggaccttagg aactccgcct ggcaccacat ctaccgcata
    33481 gacgctgaca cgccgacttg gatcagtcgt gaagccttcg actttcaagc ggtcctgaca
    33541 ttcagcagcc gcgccgcagt ccacgaccgg ccccctcgtt cccagcagcg actcctccag
    33601 gctcacgtac gcgcgcccac cgggcttggt gtagataccg acgttcgcga ccagcgtatg
    33661 cacggacaga aaatctcctg ccagcggatc acgagccctc gtccccgaaa acgtgatgta
    33721 gtcgccaacc cgcaccgggg cttgcttatt cgcatcgcac gacgggcagg ccttgatcgc
    33781 attgtttcca aacttgaccg gcggcaccag atcgacggag tccatgacga aggtgagctc
    33841 cgccggtcga ttctgactcg ggcattgcgc gtcattggtg gcgcgcggca cgcacatggg
    33901 atagccggtc agcgcatgca ccgtgggatt gccttgatcg acggtaaaac gtggatcagg
    33961 gtagcgagag ttcggatcat ccagaccaac cggtgggggc gccggattcg gcttgccgta
    34021 acgaccatct cctgcaaagg gatccgaggc atccaaggcg ggatcattca ggcgaatgcg
    34081 cgtatcgttg ccggcgcagg ccgctgctgt cggactcccc cccacacaca tcatgccggt
    34141 cgccgtatcg atgtgatgga tgaaaccggc gccggtattc aacgattgtt gcgagatcgt
    34201 gactagcccg gcgatataga gcccattgac aatattcccg ctgacgtccg cttcaaaagc
    34261 cgccaatggg ggaaacttgt cgctcagtgc aagcccggat tcgccatatt tttttgagac
    34321 gccctgggcc ttatcgaaga gttgctgcgc agtgaagtac gcggcgggca actgaatcac
    34381 gagattcttc ggcagcacca cctccacgcc attcaccgtc agcttagcgc cggacagggg
    34441 atccgccggg ctgtcgagcg tgagccgctg gatgtgtccc acgatgtgaa agggaatcac
    34501 cgcctgcgac aatgcatggc gtggcggagc tatacccaat aagacaagta caccgatcat
    34561 ccatacggtg acagtggacg gtacacgcat cgagaatcct cctcctggaa acagacggcc
    34621 acctaacttc aatgtattga catgggatca ggcccggaag cagcaacccg cacgatggga
    34681 gtacgtaggg gtatgactac tgagtccgca tgaggccggg cacgagatac cagattgcac
    34741 aatacttgcc aagctatttc ctgcctgacc caacgaataa atacatacgg cgaggctcac
    34801 ggatggaagc gtgaccatcc tcatccccga gcaaatgcgg ttttcacgta tgcacaatgc
    34861 tctgagtggc gctgtgtgcg agcaatgctt tagaaagatg aatagcttca attgtggcgc
    34921 agaggatgcg ccgtctgcag aggatgggaa tggtttctta tcgatttgga tacaaggcag
    34981 tattggaatg gatacagaat ggattcaggc ggtgcgtatc acattgatac ggcacttctc
    35041 acttcaggcg attcactaat agaacagaac cgcagcgctg cacctccgct cagtatttct
    35101 ttctgaactg cggaggcgcg tgtggcggtg gcgaaggacg cggtccctgc a
//
LOCUS       DAOQPD010000035        34706 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_519_length_34706_cov_25.439208, whole genome shotgun sequence.
ACCESSION   DAOQPD010000035 DAOQPD010000000
VERSION     DAOQPD010000035.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 34706)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 34706)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34706
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_519_length_34706_cov_25.439208"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            45..1007
                     /locus_tag="PK063_09825"
     CDS             45..1007
                     /locus_tag="PK063_09825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
                     /protein_id="HMZ97391.1"
                     /translation="MRSHIKVQMGIGVLLVAGATSFAIAADASNENKDMVLVPKGEFI
                     MGSNEHSDEVRHQVVLDAYLIDKFEASNARYKEFMRATGHPAPAYWDDPRLSKPEQPV
                     VGVSWTDANAFCKWDGKRLPTEAEWEKAAKGPEGDNHYPWGHHLDPKKANYGQNVGRT
                     MPVDSYPEGVSGYGVYNMAGNVFEWVDDWYDPKYYKTSNALNPKGADKGYNFANQGPV
                     KVLRGGSWLAPETSLHTSHRFWNQPENNSYGVGLGFRCAKSVTAVSEEAAQAGRDAFI
                     QALVGMGAEKNADAMASIEKALAADPNNKEYLATRELIQKSMKK"
     gene            1074..2132
                     /locus_tag="PK063_09830"
     CDS             1074..2132
                     /locus_tag="PK063_09830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
                     /protein_id="HMZ97392.1"
                     /translation="MTVMGTVVRAGLVMGIIAGASVAQAHEAEIPKDMVYVGQGPSIM
                     GLDRTEAAAPTRRLSLYDKRMSMPWSAEAFHDEGPAHTVFLDSYLIDKYEVSNKDYGE
                     FIKATGHPAPAYWDDPRLNKPQQPVVGVNWIDAKTYCEYRGKRLPTEAEWEKAARGPN
                     GNLYPWGNDFDSNKANYDRHHNATQPVDAHPEGASYYGVYNMAGNVFEWVGDWYDPKY
                     YGRLETMVNPTGPEKPLWLGGTGTYVDRLTVGEKRVIRGGSWIAPEGTIRSTHRFWNH
                     PLNNSYGVGLGFRCAKTAPPDWEQRIRDSYITALVEMGRERFAEAQQAVARGLAMDPV
                     NVELLELRPLIEQSMKRP"
     gene            2186..2554
                     /locus_tag="PK063_09835"
     CDS             2186..2554
                     /locus_tag="PK063_09835"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97393.1"
                     /translation="MRYRTIVTIIGGLAALVSAMELQAGPIDASRHTHPEKVQLVHEA
                     EHSVDHAWEVYHRAALGGTVASPDLQAQIEQHLHEARTLVTKAQEAADRGDAGAVEKL
                     VAQIKTHTERAIEGSKEQKK"
     gene            2551..3414
                     /locus_tag="PK063_09840"
     CDS             2551..3414
                     /locus_tag="PK063_09840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
                     /protein_id="HMZ97394.1"
                     /translation="MTQGLTRRRTRWGYAGLLAAGCTLALSPVFAAPAVKELDPVLMV
                     TIPAGPFLMGTQSPKGRADEWPQRTVQVDAFAMDEVEVTNERYMTFVTTTGHRSPPNP
                     YGTGVLVSAKGIEQLPVVQVTWYDAKAYCAWAKKRLPTEAEWEKAARGTDGRTFPWGE
                     DTPTSKRANYDREWVEDKTLHPVGALPAGDSPYGIKDMSGNAREWVQDWYDPDYYANA
                     PTKNPQGPDKGIVRVIRGGSWHSPHSDITSTARGRGGFALQTHGTGFRCVRSLDGQAH
                     QDASGAEPKAR"
     gene            3598..3729
                     /locus_tag="PK063_09845"
     CDS             3598..3729
                     /locus_tag="PK063_09845"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97395.1"
                     /translation="MTQEMILGMAAFVVSIGAVLYVRLRRPAYVMVRRSSREHPRVR"
     gene            3906..4178
                     /locus_tag="PK063_09850"
     CDS             3906..4178
                     /locus_tag="PK063_09850"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97396.1"
                     /translation="MTQHYIDLLDDTGQIDITAWHCAMCGEVLDPVILKNRHSPPPNL
                     LYGTKERKFSQRVTAVSNGGASKKSSHREAAPDKGKDSETGADRAP"
     gene            4209..5126
                     /locus_tag="PK063_09855"
     CDS             4209..5126
                     /locus_tag="PK063_09855"
                     /inference="COORDINATES: protein motif:HMM:TIGR01777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01777 family oxidoreductase"
                     /protein_id="HMZ97397.1"
                     /translation="MNIVVTGGTGFIGHALVEELSHAGHDVVVLSRRPHSPTQSKVRY
                     VEWDARSVGPWQDAVAAADAVVNLAGEPIAEGRWTSARKRILFESRILATRSLVDAIA
                     TRSRPLPVLISASGIGYYGLQDDRVLDERSPLGEGFLAQLSAAWEAEALRAGQFGTRV
                     VLLRTGMVLERDGGALPKMMLPFRLFAGGPVLPGTQWVSWIHRADLIGLMQWALHSPE
                     VSGPVNAVAPGPETMKAFCGILGKVLHRPSWLPVPGLALRLGLGELGTLMTTGQRVDP
                     AKAQAGGYRFRYPTLEPALRAIMTKEQRA"
     gene            5123..5599
                     /locus_tag="PK063_09860"
     CDS             5123..5599
                     /locus_tag="PK063_09860"
                     /inference="COORDINATES: protein motif:HMM:NF025046.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4149 domain-containing protein"
                     /protein_id="HMZ97398.1"
                     /translation="MSLLVESIMQYLHGLAAAILVGKVVLLSFVVAPVLAKQLAPEQF
                     GKVVRQLFPAYYLLGMGAAAGGLVSVTALLVIRGASPGLSAAGGIWLIIFLAEAYCRS
                     PLTPQSNAMRDQLKEQESRGSVDQVLKASWERLHQRSLYLNSLVLLGGLCLVGLAS"
     gene            5624..>5841
                     /locus_tag="PK063_09865"
     CDS             5624..>5841
                     /locus_tag="PK063_09865"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97399.1"
                     /translation="MMRKHTYRVAWMTLGVLSLCLSQWPEGTGKSWAAEGHEKSGTPG
                     GSYGLEVTIPDGVIGVSLHVGAERVGDTA"
     assembly_gap    5842..5941
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            5982..6506
                     /locus_tag="PK063_09870"
     CDS             5982..6506
                     /locus_tag="PK063_09870"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97400.1"
                     /translation="MKRMIALLGCFVMISGVCLTEVRANPTPASTLSGVEKTGLYLLA
                     GDYRRALESCEQALQERPSVEAYVRLTYVYQAIDAYLEQLSKDESWMAVEHLYLNLAY
                     RHTEDLVDPPGGLARMAKEMIQTSVRQQSDVSAAMAVRLNKVASDRLWQEQTQWRQAH
                     PTTWWQAFPDAWVQ"
     gene            6556..6987
                     /locus_tag="PK063_09875"
     CDS             6556..6987
                     /locus_tag="PK063_09875"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97401.1"
                     /translation="MIQQTSQRGIDIKLFGALFLLVGLLDVLIIEWFPAYALKLFGVT
                     ITGPMAYVVKLHSPAAHFLIGYGFIFLRPWAWGLAMAYGGFGLTSELMNQWQFGFHQL
                     RTGFMATTALFLCYVAWRRVLFVDPLSPDTRLASSSREVHL"
     gene            6984..8423
                     /locus_tag="PK063_09880"
     CDS             6984..8423
                     /locus_tag="PK063_09880"
                     /EC_number="4.1.99.3"
                     /inference="COORDINATES: protein motif:HMM:NF015406.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003904 - deoxyribodipyrimidine
                     photo-lyase activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HMZ97402.1"
                     /translation="MRGLVWFRRDLRLHDNPALSAACKECKEIVPLFVFDEPLLASHV
                     FGSVCVGFMLGCLEDLRRSLAEQGVTLVWRMGEPIDTVLRTVQECAVDAVYWNRDYEP
                     AAVARDRTVQQRLAQQGRLVRTFKDHVVFEAEEVRGLTGDPFQRYSAYRDRWWTQWRS
                     AAPPLLSVPSFPAASTAMKVSAWPTVQELGYESVPMWIEPGEQAARARLQWFLKKPVH
                     SYVSGRNLPAQDGTSKLSPHLRFGTISTRTMVHAALQTLSKGGQVSRPDVFTWMDELV
                     WREFFQQVLMAFPHVTEGPFKVKPGLPAPRPAGPERDRLFAAWCEGRTGYPIVDAGMR
                     QLNQTGWMHNRVRMVVASFLVKDLRIDWQSGERYFMQHLVDGDVAANNGNWQWCASTG
                     TDAMQGYRIFNPTLQSEKFDPDGHYLRCYVPELTSVPTKWIHEPQLMPQEEQIRVGCR
                     IGSDYPEPIVNHRQARQEYLDLGKQKVST"
     gene            8420..9373
                     /locus_tag="PK063_09885"
     CDS             8420..9373
                     /locus_tag="PK063_09885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 and DUF1722 domain-containing protein"
                     /protein_id="HMZ97403.1"
                     /translation="MTAATLRLGISRCLLGEEVRFDGGHKRDAFLTDVLGRYVEWVPV
                     CPEVEAGLGTPREAMRLVGNPQQPRLVTLKSGQDHTRALEVMADRRLDELAGADLSGF
                     VFKKDSPSCGVERVRTYNEHGMPGRKGVGLFARAFLGRFPLIPVEEEGRLCDPLLREN
                     FIERVFCYRRWRDLMNSGATRQAVVRFHTVHKYLLLAHSAPHYRQLGRLVARVSEYRP
                     KDLALQYGELFMQALAVRATVRKHVNVLHHILGHFKERLDAQEKAELLGVIGDYHQGL
                     TPLIVPLTLIKHYVQLFDVEYIREQVYLNPHPKELMLRNHV"
     gene            9384..9752
                     /locus_tag="PK063_09890"
     CDS             9384..9752
                     /locus_tag="PK063_09890"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97404.1"
                     /translation="MPHVVVEGAGDLQSLYQNFAPMLQRADQEILKVQEFYLAKSGRE
                     ALLDAVVIEQGVARSFFIQLKQHDTTITVRLLPATDPEKTAAVKRVMALVAKFIRTVC
                     PASRYGKTNLQEFLEASVAK"
     assembly_gap    9874..9973
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            10261..10836
                     /gene="pyrE"
                     /locus_tag="PK063_09895"
     CDS             10261..10836
                     /gene="pyrE"
                     /locus_tag="PK063_09895"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: protein motif:HMM:TIGR00336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HMZ97405.1"
                     /translation="MLQDELIAAFHKTQSFKWDPKGGFKLASGLLSPFYVDCRTLMAF
                     PHARHLVAKKAWEVIKDLQIDCLGGLEIGAISIATSISDYAYSAAPRREWRTFFVRKQ
                     AKDHGLGRLVEGVVRTGDRALIVDDVLTSGGSVVKTIVAAREAGLEVTDALVIVDRKE
                     QDGRARVEQTGVKVMSLLTIDDLMKGGPIPI"
     gene            complement(10837..11148)
                     /locus_tag="PK063_09900"
     CDS             complement(10837..11148)
                     /locus_tag="PK063_09900"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97406.1"
                     /translation="MKRWSSCTVLTVSLFLSSCGEGALLVKDSADGGVVVYPYRAEQG
                     TLLSSFRKEAVRLMEQKCPGGYAIVREGETKGRLRQASPVAGSSDVVEERRWGIQFQC
                     K"
     gene            11214..11645
                     /locus_tag="PK063_09905"
     CDS             11214..11645
                     /locus_tag="PK063_09905"
                     /inference="COORDINATES: protein motif:HMM:NF012790.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HMZ97407.1"
                     /translation="MRYLTSIMCGLCLCGLLFLLDVPQPAVAYHSYVLSVQQLRAGLM
                     KASSTNAKGFVLVDVRSPEEHASGMIPGTDLNIDFREMKARHRELGAKLEDHIVVYCQ
                     SGHRSNIAAETLADLGYTHVYNVVGSMNAWTEAGFPVSPGR"
     gene            complement(11647..12402)
                     /locus_tag="PK063_09910"
     CDS             complement(11647..12402)
                     /locus_tag="PK063_09910"
                     /inference="COORDINATES: protein motif:HMM:NF021507.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiester glycosidase family protein"
                     /protein_id="HMZ97408.1"
                     /translation="MEACPQVPSLLMLQIDPERYRFSIHQFRDEGLRSPISIHDWQQR
                     TDAYVLFNAGLFREDYSYLGVLLKEGRSLGTKKHHSWQGLFAAEPTDGTLKKARVLDL
                     AYEGFTEDPPLYREAAQSLMLFDRTGKLRVKDSGKRAFQTVVAEDGQGAILVIKTVDI
                     VSLHHLADCLHRQLPALQQAMAMDGGASSDVIASPDLLHAAQETSSQAGWRSLLAGTT
                     GVHIPLPTVIGITPRTPSRSTPAHGPSQSTRAH"
     gene            complement(12701..14344)
                     /locus_tag="PK063_09915"
     CDS             complement(12701..14344)
                     /locus_tag="PK063_09915"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ97409.1"
                     /translation="MMTQPLRFIHLESNPADADLIDSTLREAGILCQPKRVHTREDFL
                     AALRQESFSLILADTTVPGFDGAAALGLARTLHPDVPFLFVSATQGEEFAIDMMQRGA
                     TDYIFKQRLGRLVPSIKRTLRELDERLERRRAEDALRMSEKQFRQAQKMEAVGRLAGG
                     LAHDFNNLLTVIMGHSQVLLGELPAGNPIRVKIEEMQKAGERAASLIRQLMAFSRKQP
                     VEPQVLPLNAILANVEGMLRRLIGEDIQLVIRPDPHHGHVKADPGQLEQVLMNLVVNA
                     RDAMPNGGLLAIETSQTELARTPMHHLHPLPLGHYVKLTVTDTGCGMDAEVLAHLFEP
                     FFTTKEEHKGTGLGLSTVFGIVTTCGGGIDVWSQVGHGTTFDLYFPRANPQTSAARSE
                     KPQSRPREGSETILLVEDDGGVRDLIRHELVKTGYQVIEAKNGVEACLTATQQSYHVD
                     LLLTDVVMPGMNGRELAQHLSVIKPNLRVLFMSGYLDDICVNSGMDPHRTTFLQKPFT
                     PDILLRTVRALLDSSSPATGQTQHPFSPPDQAPRTARAS"
     gene            complement(14362..14829)
                     /locus_tag="PK063_09920"
     CDS             complement(14362..14829)
                     /locus_tag="PK063_09920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ97410.1"
                     /translation="MIASKPILLAEDNPRDAELALAAMEEHHLADKVILCHDGAEVLD
                     YLYCRGHFKTRLQGNPAVVLLDLKMPKVDGLEVLRTIKNDAALRPIPVVMLTSSREER
                     DLAESYALGANAYVVKPVEFHQFLKAVKELGVFWGMINEPPPEGASRSAGRSS"
     gene            complement(14826..16322)
                     /locus_tag="PK063_09925"
     CDS             complement(14826..16322)
                     /locus_tag="PK063_09925"
                     /inference="COORDINATES: protein motif:HMM:NF017077.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHASE3 domain-containing protein"
                     /protein_id="HMZ97411.1"
                     /translation="MNEPNRHQPVDVGLDSAFPPASPAEEKSSGRVSFLSPLLHTFQK
                     RSIEQRVLAGFGLVFAGILVISAISYRNMTVLIRNGDLDKRSHEFIQFLGATGEAIDD
                     AENGHRRFLVTGDESYLAAYNTLRDRAPEYIRYLRELTDPGSTQRGHVSDLEHLINQQ
                     LQEEHAAIELRAKTGFDSVRGMALTGVAKTALDSARRLQAQMDQEETKALTQRVVEST
                     TTTRSSIILLTIGALLLFVLLAAVYYLIRHDITERRRIADELHRRGELLEAANKELEA
                     FSYSVSHDLRAPLRHIDGYASLLAKAASISLDDKAKRYLQTISESATRMGQLIDDLLV
                     FSRMGRQEMLRGTVNLNQLIAALRHDLRHDLQDRAISWTIAQLPEVTGDAAMLRQVFM
                     NLMTNAIKFTGTRPQATIEIGSLDNGPDEAVLFVRDNGVGFDMRYANKLFGVFQRLHR
                     ADEFEGTGIGLANVRRIIHRHGGKTWAEGALGEGATFYVSLPRVRPLA"
     gene            complement(16481..17977)
                     /locus_tag="PK063_09930"
     CDS             complement(16481..17977)
                     /locus_tag="PK063_09930"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:TIGR01770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA];
                     GO_function: GO:0048038 - quinone binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH dehydrogenase (quinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit N"
                     /protein_id="HMZ97412.1"
                     /translation="MTFSLTLSASDLLLLLPELFLTLWLCVVLAVDFSFKRIVQEQLA
                     YLTILGVIITLACLAWFDMTGITGTLFGKMFVVDRMAIFFKVMILLATILVILLSIDY
                     VHRFSLFRGEYYFLVAMSALGMMFMASANDLLSLFVTLEFATFGFYVLVSYLRDDMAS
                     NEAGLKFFILGVFAAGLLAYGISLVYGETGKLVFSDMSGANPTTGLVIGFLLIFAALG
                     FKIGAVPFHSWIPDTYHGAPTPVTAFLSIAPKVAAFAILLRLFLVALATFKPAWALLI
                     VAASILSMTYGNIVAIAQRNIKRLLAYSGIAQVGNVLIGLAAGTKMGTDSILFYLLTY
                     LFANLGAFAVIMAISNSVGSDEIDDYRGLNRRSPFLAFAMLIFLLSLAGVPPLAGFIG
                     KLYIFVAAIKEGLYILITVGLVNIVVSMYYYLIVVKKMYINEPLDSSPIKTTGPLRAV
                     IYVGLAGTLVIGIYPQPFLDWAVAATLMFSNLIGPAASLTPPVTPFGG"
     gene            complement(17974..19629)
                     /locus_tag="PK063_09935"
     CDS             complement(17974..19629)
                     /locus_tag="PK063_09935"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: protein motif:HMM:TIGR01972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit M"
                     /protein_id="HMZ97413.1"
                     /translation="MAEYTLLIILFAPFLGALGLIFVSNRQVSLVRGIAAGSAFVSLA
                     ASVYLFYAYDSVKGGYQFIQRIEWSRQLGISLHLGVDGIGTPLVLASGILLFAGIFVS
                     WHIKDRMKEFYIWILILAAATIGVFMSLDLFFLYFFYEMSVIPMYLLLGMWGSHTKKY
                     LEMTDPEGLKQRDSVGFIFNFGANSKEYAAMKLVLFLSAFAVAALMGILLIYKFSGLN
                     TFDILILREKAHFSGPLATLIWLLIFFGFASIAPIWPLHSWSPVGHAAAPAATSMLHA
                     GVLMKLGHFSIIRVAFEILPETTRELMPIAAVLCIFSIIYGGLVAYYAKDTKYVIGYS
                     SSSHMGYVFLGMAALDYISLSGAVIYMFAHAMATGMLFAMAGWVYDQTHTRDIPSLGG
                     LSNRMPFISAAFVIGCMASIGMPGTVNFIAEVMIIVGSWNKYPFQVVVAVLGIVLTMA
                     YLFKMMRGLFYGSMAEKYSHSHDAVAVVDRMPLLIMITVSISFGIFPGHLYSVVRSGV
                     DPLIARITKVVPVAELPMNIPQASSHTMPVPVPGEAIAKVTSR"
     gene            complement(19633..21192)
                     /locus_tag="PK063_09940"
     CDS             complement(19633..21192)
                     /locus_tag="PK063_09940"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: protein motif:HMM:TIGR01972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit M"
                     /protein_id="HMZ97414.1"
                     /translation="MLEEFSFGFPILSYLIFLPLVGAAVLWLIDDEDLLKSTTLGITL
                     VELALACLVLVRFVPDSAAMQFAEHARWMPALGIGYHLAVDGISVLFVGLTAFLTVLV
                     VIYSWDTIRNQVRLYFMALLALETTTIGIFVSIDLILFFVFWELMLIPSYFLIKLWGG
                     GADRHYAALKYVLYTLLGSVFMLVGIALLDINYHQWAVSHHMDHVYSFDLLELLSVPI
                     PLSQQILIFWLMFMGFAFKAPVFPFHTWLPDALVEGPIGMAVMLAGMKLGTYGFLRFT
                     FPLVPDASKSEGVVGIVMVLALSAILYGAVVALVQSDFKRLLAFSSISHLGFVVVGLF
                     ALNFQGLQGSLLTMINLGFSTAGLFFMAGFLSTRQQSSHLSSFGGFAKQAPLLATFLL
                     LIGMASIGLPGTNGFVGEFLILLGAFKAKWWFGAVAVLGVIFGAAYFLWYYERAMLGP
                     LSKHVSAAVKDLHMREITIALSLSIMILWIGLYPSPFLRMMNGSIQALVDRLDRAKVA
                     SVDTVIHVPAK"
     gene            complement(21216..23219)
                     /gene="nuoL"
                     /locus_tag="PK063_09945"
     CDS             complement(21216..23219)
                     /gene="nuoL"
                     /locus_tag="PK063_09945"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_process: GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit L"
                     /protein_id="HMZ97415.1"
                     /translation="MSDSIDLIVKLIPLFPLMAVIVNGLFGHRYSHDLAHRFAWGSVL
                     MSFLCVLAVFTETLRTGAAREVIAYKWIFGGDLTINLAYLIDPLTCIMLLVITGVGFL
                     IHVYSVGYMHGEAGFTRFFVYMNLFMVSMLLLVMGNNYVVLFIGWEGVGLCSYLLIGY
                     YYDKVSAAKAATKAFVVNRIGDAGFLLAIFLVFVNFRTLDYTQVMQNAAQLSPEMATA
                     IALCLLVGAVGKSAQLPLYTWLPDAMEGPTPVSALIHAATMVTAGVYMIVRNHAIFDL
                     APMAMTTVAWIGGLTALFAATIGLVQTDIKRVLAYSTVSQLGYMFLGCGLGAYTAAVF
                     HLMTHAFFKALLFLSAGSVIHALSGEQDIRKMGALKSKIPWTHTLFLIGTIAIAGIPP
                     LAGFWSKDEIMGHAFVHHHYLLYGMAAVGAFLTSFYMFRLTYLTFYGTSRLDHHTAEH
                     VHESPMVMIGPLVVLATLSVIGGFPGVPPENGWFHHFLHSVAGVAGEEHATPPALMFG
                     LMGTATVIALLGWGLAHYFYSGPSTAAAALADRMPGAYTTLLNKYYVDELYDTLFVEP
                     TKQLGRLCDWFDRTIIDGLVRGIDRGTDLSSAAITWTEKHVVYAGLNIIGYANHLLAR
                     SWRRLQTGMVHQYAAIIVAGLFILVHLILLIWTGGGSTGYSAR"
     gene            complement(23221..23523)
                     /gene="nuoK"
                     /locus_tag="PK063_09950"
     CDS             complement(23221..23523)
                     /gene="nuoK"
                     /locus_tag="PK063_09950"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA];
                     GO_process: GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoK"
                     /protein_id="HMZ97416.1"
                     /translation="MIPLSAYVAVSAILFTTGLLGVLIRRNFIIVLMSVEIMLNAATI
                     NLVAFSHYLESMQGQIVALFIIAIAAGEAAIGLAIIIVVFRGKISTNVDEMNLLKW"
     gene            complement(23520..24044)
                     /locus_tag="PK063_09955"
     CDS             complement(23520..24044)
                     /locus_tag="PK063_09955"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: protein motif:HMM:NF012709.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit J"
                     /protein_id="HMZ97417.1"
                     /translation="MAFVFFAYFAVVSIVAGILTVALKNPVQCGLALLALLLHVSGLF
                     VMLNAEFLWAVQVIVYAGAILVLYLFVLMLLNLKTDDRYFHARTPYLLAPAVIGLIYL
                     LFLLIRSPFSGSRGDASTAAVLLNGDAHAVGIKMFSDYLLQFEIIGVFLTGAIVGAIV
                     LAKAPKSIETRRDA"
     gene            complement(24056..24643)
                     /gene="nuoI"
                     /locus_tag="PK063_09960"
     CDS             complement(24056..24643)
                     /gene="nuoI"
                     /locus_tag="PK063_09960"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoI"
                     /protein_id="HMZ97418.1"
                     /translation="MSVGALTKKVLQAALFYEIWDAMKVTFKHMFHRPITFQYPREQR
                     TIPDGHRGALGLLRYSDGRDRCVGCDLCEAACPSRCIKVISQEDPERPLQRFASEFYI
                     DITKCVFCGYCVEACPVNALAMTKMYEYSTHDKRTLLFDKKRLYEVGERHLEDAKKYL
                     YTHNQEKNSDESREYRYYFPQSVLKPTQSQPKHLS"
     gene            complement(24688..27381)
                     /locus_tag="PK063_09965"
     CDS             complement(24688..27381)
                     /locus_tag="PK063_09965"
                     /inference="COORDINATES: protein motif:HMM:NF012602.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HMZ97419.1"
                     /translation="MKPATNPDVEAATIELSIDGRTVSAKDGVSLYDVIASTGKIIPA
                     MCYHYTFDPFGSCGMCLVMQEGKKAPVRSCTAKAAAGMVIRTDGDDLFAARKKAVEKH
                     LSVHPLDCPVCDADGHCELQDMAFQHGVTNLANAKQKFIPEDTRSLVLDFNMNRCIAC
                     AECINVCKDVLMIDALQFMKKGGFNQVVAKGDQPLACEFCGDCLAVCPVGAITNKYSK
                     YLYKPWQMRKTTTTCNYCGDGCQMHLETKDTEVVRVTSPLSWKNKWGDRSETAKGHGG
                     LCVRGRFGFQYIDSQQRLRQPLVRTGDTLKETPWLDAMQTVIDQLSDIHRKHGPESIA
                     GLITARCTNEELYLFQKLMRGGLRTNQLDSSARYGHLNYVHAVRHAVGIGRPLNDWED
                     LTKAKAVLVIGSNITETNPLTAVRIKEAIRVYHAQVIVVDSSNTNIAQLASHPLLVKP
                     GTEALLIDGLVKAVIEQDLVDETSTTQHPQAFAALKQAVAQISLDEVSRTTGISVDQI
                     REVAAIFAEAPRAVALCAEGIVRRPNGYENVLKLVDLAWVTGKLGQPGCGVTTVTEEV
                     NEQGAIDMGVAPEFLPGQARFDDPGARERFGKAWEVTLPAIGTGANLLEIFTRIQKGQ
                     IKALYVIGENPLATLPASMDVKGALDKLQLLIVQDPFLTETGRMAHVVLPAATYAEKD
                     GTFTNLEGKVLRVRQALDQVGESLPDWHIMTALANGLGYEWPYQSPQDVQNEIMKLLP
                     GYYNLGQPRRIAPSADAYLSNGYSSEVVTRYRRRQAMDDTSRPFTLVMGQVLYHSGKM
                     STQASGLINIEPNNGRIRMNPADVEKLGLTEQSTVRLSSQQASVQAGVKADPDVQSGS
                     CFFPEHFNEPPIKDLMTTEVDAVTGVPYFKSTRVKIEKVGA"
     gene            complement(27467..28714)
                     /gene="nuoD"
                     /locus_tag="PK063_09970"
     CDS             complement(27467..28714)
                     /gene="nuoD"
                     /locus_tag="PK063_09970"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050136 - NADH dehydrogenase (quinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase (quinone) subunit D"
                     /protein_id="HMZ97420.1"
                     /translation="MAQFEDQRTTVYKIDPEHPESETLPTLRTEELLLNMGPQHPSTH
                     GVLKVILELEGERLVKSTPVMGFLHRGVEKLAEEGTYHQFIPHTDRLDYVCAMYNNFA
                     YCRAVEKLMNITVPDRAEYLRTIVAEIQRIIGHQFWLGTQALDIGAMTVFFYCFRDRE
                     ILLDWFDELCGARLTTSWYRIGGVERDFTPSLFAKLKQFLDYFPPKIDEYVIFLEKNR
                     IWLARTKGVAVISAEDALSFGLSGPTLRGSGVDFDLRKYEPYSAYPKCEFSVPVGKNG
                     DTYDRYWIRVQELYESVKIIRQCLEQIQDGPIMADVPSVTLPPKERVFTNLESMIQQF
                     KLFSQGFNAPPGEIYCGTEAHKGELGFYIVSTGGGKPYRLKIRAPSFIHMGAFDHMSK
                     GYMISDAVTIFGTYDIVMGECDR"
     gene            complement(28743..29240)
                     /locus_tag="PK063_09975"
     CDS             complement(28743..29240)
                     /locus_tag="PK063_09975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit C"
                     /protein_id="HMZ97421.1"
                     /translation="MSQLAQRIEDTFPGACTKVVEWRGDLAVTVKPETLHDVAKFLRD
                     DPALRFDYIVHVSSVDWPDDEDRFEVVYEVYSIRTRQRIRLKTRVPESDCIVDSLTDV
                     WKGADFMEREVYDMMGIRFRNHPDLRRILMPDEYDEGYPLRKDFPLRGKGWRDTFEFL
                     DEPTR"
     gene            complement(29257..29784)
                     /locus_tag="PK063_09980"
     CDS             complement(29257..29784)
                     /locus_tag="PK063_09980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit B family
                     protein"
                     /protein_id="HMZ97422.1"
                     /translation="MGLIQLGGHDKDGSPDVITLTVEKAVNWARKGSLWPMTFGLACC
                     AIEMIAAVSSRYDMDRYGAGVFRASPRQSDLMIVAGTVCRRMAPVIRKIYDQMPEPKY
                     VIAMGSCATSGNIYDSYSVVQGVDRFVPVDIYVPGCPPTPEALFDGILKLQERIMQKR
                     VFLSQPKEVKDALKV"
     gene            complement(29775..30158)
                     /gene="ndhC"
                     /locus_tag="PK063_09985"
     CDS             complement(29775..30158)
                     /gene="ndhC"
                     /locus_tag="PK063_09985"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit A"
                     /protein_id="HMZ97423.1"
                     /translation="MAGSELLLEYLSRYFPVLVFVFIALAFGAGTLIISYFVQPKYPE
                     PEKLSTYECGSEPFSDARMPFPVRYYIFAMLFVIFDVEVIFLYPWAIVFNKIGLIGLI
                     EMLIFIGLFLVAYVYAWRKGALEWD"
     gene            30707..32266
                     /locus_tag="PK063_09990"
     CDS             30707..32266
                     /locus_tag="PK063_09990"
                     /inference="COORDINATES: protein motif:HMM:NF012894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HMZ97424.1"
                     /translation="MRTLSMRASLTILSCSLMAVTAIPVYAQNAQSVRLGEAALTYAA
                     GSIRQDMPIEGVINVITGDNQLSGNRMMLGWSGTDTLYLKLKIPGDAALGDLYTVYRR
                     SRKVFHPITKQYLGYVINRVGVVKVVQLDPVLVGVQVVRSYAPLSPGDPVMRFTPPAA
                     EEVSEPVSSGPDVEGMIVELQADKHMSLVSQGNVVYLDKGRDDGLRSGDSMEVFRTGG
                     GLPERKIGEVRVLATEPHTATAVLSKASARALVGDRLRSKHGVPVEAMQPESGEIDRQ
                     AATVQPVMVAKTDASVREANGGRLPATGKIERTRGSRRLNLDDLADQLEYESGEVKVK
                     PAGVPILEKLTEYLTTTATGQQVRVEGHSDNMEIGPSLKGVFPTNWELSKARAAEIVR
                     YLVEKGGMDSAKLSAVGYGASRPVASNGTEEGRKRNRRIEVVLESLEEAAPAQPVKAS
                     VDETASVSTQFTYNQMNAVPVNPTSVPVSEVPSGPAPSDVTPERGPIAPEAGVPASPA
                     DGMPPSPAPGS"
     gene            32428..>34706
                     /gene="priA"
                     /locus_tag="PK063_09995"
     CDS             32428..>34706
                     /gene="priA"
                     /locus_tag="PK063_09995"
                     /inference="COORDINATES: protein motif:HMM:TIGR00595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005658 - alpha DNA polymerase:primase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HMZ97425.1"
                     /translation="MLDPPLQQPSAMIPAPSPAYVDVVLPRRLHRPFTYIIPSELKGR
                     VAIGRSVVVPFGSQDLHGLVIAVHHRLPPGAPQKGLKAIRSLSAASADHLLTAGQIGL
                     SHWVAERYAAPWGQCIKLVLPPVDRVGASQPRYMATAQGLATNASVEPLGETETELLA
                     RLRRRPQGIMATTLLKGDRSRTTLALQALIQKGLVSRCEERAAQKSVRPANQQSQLSG
                     GGLPMESVEAVENLELPHAEAMSWSAVLEQALAKKTFVSLLLEGSHCTRQWCLAQAVR
                     ATLRLGRQALILTGDVEHASRLADSLAAGGEQPMLLHSGLSMTARAAVWQAAQEGSVR
                     ILIGTRMAVFAPLRRLGLVWVDGEDDASFKEEQVPRYHAREVAHYRASRDGAVLVLAS
                     NHPSLESLSAVQEGRMTACKYRDAGELPAVHVIDMKEYPRDASGGTVLSPPLTEGLRE
                     ALRQHALSILYLNRKGFASVLHCGDCGAMPQCDACSVALTFFRRSNHVRCHYCGRTKP
                     VPEHCSRCQSLKLEPVGSGTERVEEAVRRLFPQARVGRVDGETIRRPADARALNRLLA
                     AGELDVVIGTQMIFRLGLEGRALCVALPDADAGLHIPDFRSAERMYHALRDAAELARP
                     ASEGGRLLIQTRLADHHAIMALSCGDEEVFVRQEQAFRQMLQYPPWTRLVRLDVSGTQ
                     EAMVSQAADRWAALLKAQAAGREPMVVVLGPSPAPHVLRRGRYCWQILIKSASLEAGK
                     EIAVRTREDVERESRRGGLR"
BASE COUNT         7598 a         9209 c        10512 g         7187 t
ORIGIN      
        1 tcatggtcac acgagtcgac tgttcacaac caaggaggtt tcacatgcgg agtcatatca
       61 aggtgcagat gggaatagga gtactgctgg tggcgggggc gacatccttc gccattgccg
      121 cagatgccag caacgagaac aaggacatgg tgcttgtccc gaagggtgaa ttcatcatgg
      181 gcagcaatga acattccgat gaggtgcggc accaagtggt gctcgatgcc tacctgatcg
      241 acaagtttga agcttcgaat gcacgctaca aggaattcat gcgagccacg ggccaccccg
      301 ccccggccta ttgggatgat ccccgtctga gcaagccgga acagccggtg gtcggagtga
      361 gctggacgga tgcgaatgcg ttctgcaagt gggacggcaa gcgcttgcct accgaagcgg
      421 aatgggaaaa ggccgcgaag gggccggaag gcgataacca ttatccgtgg gggcatcacc
      481 tcgatccgaa gaaagccaac tatggacaga acgtgggccg cacgatgccg gtcgactcct
      541 atcctgaggg cgtgagcggg tatggcgtct acaacatggc cggtaacgtc tttgagtggg
      601 tcgacgactg gtatgacccc aaatactaca agaccagcaa cgcgttgaat ccgaagggcg
      661 cggacaaggg ctacaacttt gccaatcaag gcccggtgaa agttttgcgt ggcgggtcat
      721 ggctcgctcc ggaaacctca ttgcacacca gccaccggtt ctggaatcag ccggagaata
      781 actcctacgg cgttggactt ggcttccgct gcgcgaagtc ggtgaccgcg gtgtcggagg
      841 aagcggccca ggccggacgc gatgccttca ttcaggcact cgtgggcatg ggtgcggaga
      901 agaacgcaga tgcgatggcc tccatcgaga aggccctggc tgcggatccg aacaataaag
      961 aatacctggc aacacgtgag cttattcaga agtcgatgaa gaagtaaatg ctggccgcag
     1021 aggaggtggg atgaccacct ccctgtcgga ccttcagcag gaggaggtgc ggcatgactg
     1081 tcatgggaac ggtagtcagg gcgggactcg tcatggggat catcgcaggg gcttctgtcg
     1141 ctcaggcgca cgaggccgag attccgaagg atatggtgta cgtgggacaa ggcccgtcca
     1201 tcatgggact ggataggacg gaagcggccg caccgacccg tcgactttcc ctgtacgaca
     1261 agcgaatgag catgccgtgg tcagcggagg ccttccacga cgaaggacct gcgcacacgg
     1321 tattcctgga ctcctatctg atcgataagt acgaggtgtc aaataaagac tacggcgaat
     1381 tcatcaaggc gaccggccac cccgctccgg cctattggga cgatccgcga ttgaacaagc
     1441 ctcaacagcc tgtggtcggg gtcaactgga tcgacgcgaa aacctattgc gagtatcgcg
     1501 gtaagcggct cccgacggag gcagagtggg aaaaggcggc tcgtggtcct aacggcaatc
     1561 tctacccatg gggcaacgac ttcgactcga ataaagcgaa ctatgatcgg caccataacg
     1621 cgacccagcc ggtagatgcc catcctgagg gcgccagcta ttacggcgtg tacaacatgg
     1681 cgggcaatgt ctttgagtgg gtgggcgact ggtacgaccc gaaatactac ggacgactgg
     1741 aaacgatggt gaaccccact ggcccggaaa aacccttgtg gcttggtggt accgggacct
     1801 atgtggatcg gctgacggtt ggcgagaaac gtgtgatccg cggcggttcc tggattgcac
     1861 cggaaggcac gatccgctcg acgcatcgct tctggaacca tcctctcaac aacagctacg
     1921 gcgtagggct cggcttccga tgtgccaaga cggcgccacc agactgggag cagcgtatcc
     1981 gggatagtta catcacggca ttggtggaga tgggacggga acgtttcgcc gaggcgcaac
     2041 aagcagtggc tcgtggacta gccatggatc ccgtgaatgt cgaactgttg gagttgcgac
     2101 ccctcatcga acaatcgatg aaacgtccgt aacgtcggac ggaggactgt cgcacccaag
     2161 agtttcttat gacggaggca gaggtatgag gtacaggaca atcgtcacaa tcatcggtgg
     2221 gttggcggcg ctggtatccg cgatggaact tcaggcaggg ccgattgacg ccagtcgcca
     2281 cacccatccg gagaaggtgc aactggtgca tgaggcggag cacagcgtgg atcacgcctg
     2341 ggaggtgtac catcgtgcgg cgctgggggg aaccgtggcg tcacccgatc tgcaagcaca
     2401 aatcgaacaa catttgcatg aagcgagaac cctcgtgacc aaagcgcagg aagcggccga
     2461 ccgtggcgac gcaggtgcgg tggaaaagct cgtcgcgcag atcaagactc acacggaacg
     2521 ggcaatagag gggagcaagg agcagaagaa atgacacaag gtttgaccag gagacgtacc
     2581 agatggggat atgcgggcct gttggcggcc ggctgtacgc tcgcgctgtc ccctgtgttt
     2641 gcggcgccgg ctgtcaaaga gctggatccg gttctcatgg taaccattcc ggccggaccg
     2701 ttcttgatgg gcacgcagag cccgaaaggg agggccgacg aatggccgca acgcactgtg
     2761 caggtggatg ccttcgccat ggacgaagtg gaagtcacga atgaacggta catgacattc
     2821 gtcacgacca caggccaccg gagtccgccc aatccctacg gaaccggtgt gctggtgtcg
     2881 gccaagggaa tcgaacaact gccggtcgtg caggtcacat ggtatgacgc gaaggcctat
     2941 tgcgcctggg ccaagaaacg attgcccacg gaagcggagt gggaaaaggc cgcacgtgga
     3001 accgatggcc ggacctttcc gtggggggag gacacgccga cgtcgaagcg agctaactac
     3061 gaccgcgagt gggtggagga caagacgctt caccctgtgg gggccttgcc ggctggcgat
     3121 tctccgtacg ggatcaagga tatgtcgggc aatgcccggg agtgggttca agactggtat
     3181 gacccggatt actacgcgaa tgctccgaca aaaaatcccc agggaccaga caagggtatc
     3241 gtgcgtgtga ttcgaggagg atcctggcat agcccgcatt cagacatcac ctcgacagca
     3301 cgaggccggg gaggattcgc gcttcaaaca cacgggacag ggtttcgctg tgtgcggagc
     3361 cttgacggtc aggctcacca ggacgcatcc ggcgctgagc cgaaagccag gtaagcgatg
     3421 ggttcatggg ggcattcgtt gaaacgagaa ctgtggtgag catggaggta ccgcgactcc
     3481 gcacgcggcc tcccgttgag gcggatgggt gcttcctttg gaggcacctg tcccctcagc
     3541 gaaccaccag agggtgcaag aacgggcgtt tcgctcagcg ggatgaagga ggtagggatg
     3601 acgcaggaaa tgatcttggg catggcggcc ttcgtggtca gtatcggtgc ggtgctgtat
     3661 gtgcgcctgc ggcgcccggc ctacgtcatg gtgaggcgat cgagccggga gcatcctcgt
     3721 gtccgctagt gccacgagcg gccatgtatg tcggagcgga atgccaacac accagcgaaa
     3781 ggtacggtgc ggacgattat tttttatcga agtcgggggt tccaatggac acacatggga
     3841 caccagaatc atttatgcct ccccagccgg gcaagcacgt ctgtccccgt tgcggagggt
     3901 tattgttgac gcagcattat attgatctcc tggatgatac aggccaaatc gatattacgg
     3961 cgtggcattg cgccatgtgc ggcgaagtgc tggatcccgt gatcctcaag aatcggcata
     4021 gtccgccacc caatttgctg tatggtacga aagagcgaaa gttcagtcag cgtgtgacgg
     4081 ctgtttccaa tggcggtgcg tcgaagaagt cgtcccatcg cgaggcggca ccggataaag
     4141 gaaaggactc ggagactggc gccgatcgcg ccccgtagcg gacgactgcc ggaactggag
     4201 gctcccacat gaatattgtc gtcaccggag ggacaggctt catcggccat gcgctcgtgg
     4261 aagaattgtc gcatgcgggt cacgacgtcg tggtgctgag ccgaaggcca cattccccca
     4321 ctcagtcgaa ggtacgctat gtggagtggg atgcgcggtc agtcggcccc tggcaggacg
     4381 cggtcgcggc ggcggatgcg gtggtcaatt tagcgggcga gccgattgcg gaaggccggt
     4441 ggacaagcgc ccgcaagcgg attcttttcg agagccgtat tctcgccacc agatcgctgg
     4501 tggatgcgat agcaaccagg tctcgaccgc tccctgtgct gataagcgcc tcgggcatcg
     4561 gctactacgg cctccaggat gatcgtgtcc tggatgagcg atcccccctc ggtgaaggat
     4621 ttcttgctca attatccgca gcctgggaag cggaggccct ccgggccggc cagttcggca
     4681 cccgtgtcgt gcttctacgg acggggatgg ttctggaacg ggatggcggg gcattgccga
     4741 aaatgatgct gccgttccgt ttgtttgcgg gtggtccggt cttgccgggg acgcagtggg
     4801 tgtcctggat tcaccgggcg gatctcatcg gcttgatgca atgggctcta cactccccgg
     4861 aggtttccgg ccccgtgaat gcggttgcgc ctgggccgga gacgatgaag gccttctgcg
     4921 gcatcctggg caaggtcttg caccggccat cgtggttgcc ggttcctggg ctggcattgc
     4981 gtctgggttt gggagagctc ggaacgttga tgacaaccgg acaacgcgtc gacccagcta
     5041 aggcacaagc agggggctac aggttccgat atccgacact ggaaccggct ttgcgcgcga
     5101 ttatgacaaa ggaacagcgg gcatgagcct cctcgttgaa tcgatcatgc agtatctgca
     5161 cggcctggct gcggcgatac tggtgggcaa ggtggtgctg ttatcgtttg tggtggctcc
     5221 cgttctggca aagcagttgg ccccggagca gttcgggaaa gtcgtgcggc aattgttccc
     5281 tgcgtactat ctcctcggaa tgggcgcggc tgccgggggt ttggtgtcgg tgaccgcact
     5341 cttggtcatt cgtggggcca gcccgggcct gtcggcagcg ggtggtatct ggctgatcat
     5401 cttcctggcg gaagcctatt gccggtcgcc actgacccca cagagcaatg cgatgagaga
     5461 tcagcttaag gaacaggaaa gtcgtggttc cgtggatcag gttctgaagg cctcttggga
     5521 gcgattgcat cagcggtcgc tctatttgaa ttcgctcgtc ctcctgggag ggctgtgctt
     5581 ggtagggttg gcctcttaac ggtcggtctg aagaagggag tgcatgatgc gcaaacacac
     5641 gtatagggtg gcatggatga ccctcggggt cttgagcctc tgtttgagtc agtggcccga
     5701 gggaaccggc aagtcttggg ccgcggaggg acatgagaag tccgggactc ccggagggtc
     5761 gtatggattg gaggtcacga ttccggacgg cgtcatcggc gtctcgttgc acgtcggagc
     5821 ggagcgagtc ggtgacacgg cnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5941 ncagatggga tcacatggcg gctctgccaa ataggtgatg tgtgaaacgt atgatcgccc
     6001 tgctcggatg cttcgtcatg atctcgggag tatgccttac cgaggtgagg gcgaatccca
     6061 cgccggcatc gacgctatcg ggggtcgaaa aaacagggct gtatctgctg gccggtgact
     6121 atcgtcgcgc gctggagagt tgtgaacagg cgttacagga gcgcccgtca gtcgaggcct
     6181 atgttcggtt gacctatgtg taccaggcca ttgacgcgta tcttgaacag ctgtccaagg
     6241 atgaaagctg gatggcagtg gagcacctct atctgaacct ggcgtaccgg cataccgagg
     6301 atctcgtcga tccgcccggt ggtctcgcac gcatggcgaa ggaaatgatc caaaccagcg
     6361 ttcgccaaca gtctgacgtc agcgccgcga tggcggtgcg gttgaacaaa gtggcctccg
     6421 atcgcctctg gcaggagcag actcagtggc gacaggcgca tcccacgacc tggtggcagg
     6481 cgttccccga tgcctgggtg cagtgacgcg atggagcccg acggtatgac gtgtccaggg
     6541 aaggaggttg gaaccatgat ccagcagacg agtcaacgcg gcatcgatat caaattattc
     6601 ggggcgctct ttttgctggt gggcctgctg gatgtactca tcattgaatg gttccccgcc
     6661 tatgcgctca aactattcgg cgtgacgatt accggcccga tggcctatgt tgtgaagctg
     6721 cattccccgg ccgcccattt tttgatcggc tacggattta tctttctgcg tccctgggcg
     6781 tggggattgg ccatggccta cggggggttc ggcctcacca gcgaactgat gaatcaatgg
     6841 caattcggtt tccatcaact gcgcacgggg ttcatggcca cgacggccct gtttctctgc
     6901 tatgtggcct ggcgacgagt gctgtttgtt gatccgctgt cgcccgacac gcggcttgcg
     6961 tcctcgtctc gcgaggttca tttatgaggg ggttagtctg gtttcgtcgt gacttgaggc
     7021 tgcacgacaa ccctgctctt tcggctgctt gcaaggaatg caaagagatc gtgccacttt
     7081 ttgtgttcga cgaaccattg ctggccagcc atgtgttcgg atccgtctgc gtggggttca
     7141 tgttgggctg tcttgaggat ttgcgccgct ccttggcgga acagggtgtg acacttgttt
     7201 ggcgaatggg tgagccgatt gacacggtgc tgcgcacggt gcaggaatgt gccgtggatg
     7261 ccgtctattg gaatcgtgat tacgaaccgg cggcggtcgc gcgcgatcgt acggtgcaac
     7321 agcgcctggc tcagcagggc cgtctggtga ggaccttcaa agaccacgtg gtgttcgaag
     7381 ccgaagaagt gcgggggtta accggtgacc cctttcaacg gtatagcgcc tatcgtgatc
     7441 gctggtggac tcagtggcgg tctgctgcgc caccgctcct atccgtgccg tcattccccg
     7501 cggcgtctac agcgatgaag gtgtcggcgt ggcccacggt gcaggagttg ggttacgaat
     7561 cggtaccgat gtggatcgaa ccaggcgaac aggcggcgcg agccagactg cagtggtttt
     7621 tgaaaaagcc ggtccatagt tatgtcagtg gacgaaatct tccagcgcaa gacgggacgt
     7681 cgaagctttc tcctcatttg cgattcggaa cgatctcgac gcggacaatg gtgcatgccg
     7741 cgttacagac cctctccaaa ggcggtcagg tatcccgccc cgacgtgttc acctggatgg
     7801 acgaattggt ctggcgagaa ttttttcagc aagtgctgat ggcctttccc catgtcaccg
     7861 aagggccgtt caaggtcaag ccgggacttc ccgctcctcg tcctgccggt cctgagcgcg
     7921 accggctctt tgcggcctgg tgtgaaggcc gtaccggata tccgattgtg gatgccggca
     7981 tgcgccaatt gaatcagaca ggctggatgc ataatcgtgt gcgtatggtg gtggcgtcgt
     8041 ttctggtcaa ggaccttcgg atcgattggc aaagcggcga gcgatacttc atgcagcacc
     8101 tggtggatgg agatgtggcg gccaacaacg gaaactggca gtggtgtgcc tctaccggaa
     8161 cggatgcgat gcaggggtat cgcatcttta acccaacgct ccaaagtgaa aaattcgatc
     8221 ctgatgggca ttatctgcga tgctacgtgc cggaattgac ttccgtgccg acaaaatgga
     8281 ttcatgaacc gcagctcatg ccgcaagaag aacaaatccg cgtcggatgc cgtatcggat
     8341 cggattatcc ggagcctatc gtgaatcatc ggcaggcccg gcaggaatat ctggatctcg
     8401 gcaaacagaa ggtctcgacg tgacggccgc gacgctccgt ctcggcatca gccggtgctt
     8461 gcttggtgag gaggtccgct tcgacggcgg ccacaagcgg gatgccttct tgaccgacgt
     8521 attaggccgt tatgtggaat gggttccggt ctgtcctgag gttgaggcgg gactgggcac
     8581 accgagagag gctatgcggt tggtcggcaa tccgcaacag ccgcggttgg tcacgctcaa
     8641 gagcggccag gatcataccc gcgccttgga agtcatggcg gacaggcgcc tcgatgagtt
     8701 ggccggcgcg gacttatccg gctttgtgtt caaaaaagat tcgcccagtt gtggagtgga
     8761 acgagttcgg acctacaacg agcacggcat gccaggtcgc aagggcgtgg ggctatttgc
     8821 gcgggcgttt ctcggccgct ttccgctgat acccgtagaa gaagaaggac gcctctgtga
     8881 tccgttgctc cgtgagaatt ttatcgaacg ggtattctgc tatcggcgtt ggcgggacct
     8941 gatgaacagc ggtgcgacga ggcaggcagt ggtgcggttt cacaccgtcc ataagtacct
     9001 actgctggcg catagtgcac ctcactatcg ccagctgggt cgtttggtgg caagggtcag
     9061 cgagtatcgc cctaaggatc tggcgcttca atatggcgaa ttgttcatgc aggccctggc
     9121 ggttcgagcg acggtgcgca aacatgtgaa tgtgctgcat catatcctcg gacatttcaa
     9181 ggaacggctt gatgcgcaag aaaaggcgga gttactggga gtgatcggcg attaccatca
     9241 aggactcacg ccgctgatcg tccccctcac gctgatcaaa cactatgtgc agctcttcga
     9301 tgtcgagtat attcgcgagc aggtgtatct gaatccgcat ccgaaggagc tgatgctccg
     9361 gaatcacgtc tagaaaggac gtcatgccgc atgtcgtggt cgagggtgcc ggtgaccttc
     9421 agagtctcta tcagaacttc gccccgatgc tccaacgggc tgaccaggaa attctcaagg
     9481 tccaggaatt ctacctggcg aagagcggca gggaggcgct gctcgatgcg gtggtgatcg
     9541 aacagggcgt ggcacggagc ttttttattc agttgaaaca acatgacacc accatcaccg
     9601 ttcggctgct gcctgccacg gaccccgaaa aaactgccgc cgtgaaaagg gtgatggcgc
     9661 tcgtggcgaa atttattcgc acggtgtgtc cggcgagccg gtacggcaag accaatttgc
     9721 aggaattctt agaggccagt gttgcgaagt aagtatcggt ggatgtgaca ttgaatggag
     9781 gactgacgaa atggcaacag tgcggaaagg tgtgattctg gtgggacatg gcgggattcc
     9841 cagagggtgt cctcaagaca tggtgacgaa actnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9961 nnnnnnnnnn nnnctccggc ctcagtaccc tggcgtcgag ctccggtatg cctggccgtt
    10021 tgaccttggc atgatcgccg ggacgctggc tgaacaggtc cgtcgattct cttgaggaga
    10081 atcgcaatcg gttgcggggt cttgtgaacg cagctgatgg acaggactgc ggctgccagg
    10141 tcggtgaatc atttgatgcc atctgagtgg agaccggtgt acaatcagcc gccgttgcga
    10201 ggcgccggta ctgctacggt ggcttgatga atcggccttc aagggagcgc aggacctatc
    10261 atgctgcaag acgaacttat cgctgcgttt cacaagacgc agtcgttcaa gtgggatccg
    10321 aaaggcggct ttaagctcgc ctcgggattg ctcagtccgt tttatgtcga ttgccggacg
    10381 ttaatggcgt tcccccacgc ccgccactta gtcgccaaga aagcctggga ggtcatcaag
    10441 gacctacaga tcgattgcct tggcggactg gaaatcggcg cgatctcgat cgccacgtcc
    10501 atctcggatt atgcctattc ggctgctcct cgacgcgagt ggcgcacctt ttttgtgcgg
    10561 aagcaggcga aggaccatgg gcttggtcga ttagtcgaag gtgtcgtgcg aacgggggac
    10621 cgcgccttga tcgtggatga cgtgttgacg tccggcggat ctgtggtgaa aacgattgtc
    10681 gcggcccgtg aggctggatt ggaagtcacg gacgcgctgg tgattgtcga tcgaaaagaa
    10741 caggatggcc gcgcccgggt cgagcagact ggggtgaaag tcatgagtct gttgacgatt
    10801 gacgatctga tgaagggtgg cccgattcct atctgactat ttgcattgga actgaatgcc
    10861 ccaccgccgt tcctcgacca cgtcgcttga tcccgcaaca gggctagcct gacgcaggcg
    10921 acccttcgtt tccccttctc gaacgatcgc atacccgccc gggcatttct gctccatcag
    10981 ccgcacggcc tcttttcgga acgacgacag gagggtcccc tgttctgctc tgtaggggta
    11041 cacgaccacg cctccgtcgg cactgtcctt caccagaagg gcgccctcgc cgcagcttga
    11101 tagaaacagc gagacagtaa ggactgtgca gcttgaccac cttttcatag ggcttttatc
    11161 atacagcata tgtcgcacac ttattccggc tcgccaaaag gagagagata accatgcgat
    11221 acctgacgtc tatcatgtgt gggctctgtc tgtgtgggct tctttttctg ctcgatgtac
    11281 cccagccggc cgtcgcctat cactcttatg tgttgagcgt gcagcaattg cgggccggtc
    11341 tcatgaaagc ctcgtctacg aatgccaagg ggtttgttct ggtcgatgtg cgttcccctg
    11401 aagagcatgc gtccggcatg attcccggca ccgatctgaa cattgatttt cgcgagatga
    11461 aagcgcgaca tcgtgagctc ggggcgaagt tggaagacca tatcgtcgtc tactgtcaat
    11521 ctggtcatcg cagcaatatt gccgcggaga ctctggccga tctgggctat acgcatgtgt
    11581 acaatgtggt cggaagcatg aatgcctgga ccgaggcagg atttccagtc tcccctggcc
    11641 gatagatcag tgtgcgcgag tggactgtga cggcccgtga gccggtgtgc tgcgcgaagg
    11701 ggtgcgtggt gtgatgccga tcaccgtggg cagcggaatg tgtacgcctg tcgtcccagc
    11761 aagaagcgat cgccatccgg cctgcgagga ggtttcctgg gccgcgtgca acaggtcggg
    11821 gctggcaatg acatcggacg atgcgccgcc atccatggcc atggcctgct gaagagccgg
    11881 cagttggcga tgtaaacagt cggccaggtg gtggagcgag acgatgtcca ctgtcttgat
    11941 cacaagaatg gctccctgcc cgtcttccgc caccacggtc tgaaacgccc gttttccgct
    12001 atccttgacc cgaagcttgc cagtccggtc gaatagcatc agcgactgtg cggcctctcg
    12061 atacagtggt ggatcttcgg tgaatccctc ataggcgaga tccagcacgc gtgctttttt
    12121 cagcgttccg tcggtgggtt cggcggcgaa caggccttgc caggaatggt gtttcttggt
    12181 gccgagcgaa cgcccctcct tcaatagcac gcccagatac gaatagtcct cccgaaacag
    12241 gcccgcattg aacaagacat atgcatcggt ccgttgctgc cagtcgtgaa tcgagattgg
    12301 cgaccgcaac ccttcatcgc gaaattgatg gatggaaaaa cggtaccgct ccggatcgat
    12361 ctgcagcatg agcagcgagg gaacctgagg gcaggcctcc atggggttcc acaacgccac
    12421 gtgcatgcct gcggttaatc gctcccaggg gactggttct gccgaagcgg ctgccgtctg
    12481 aacccatcca tgacacagag acagaaggca gacgcagagg ggaatcatcc tgcgaaggga
    12541 tcctggtaag tatcggtgcg gattgatcat cggagcaggt ggtctttcat ggtaatcagc
    12601 caaccatggc agcgtgaaac gtctcgcgcg ggctcagtat aaaaaggatg ggggcagggg
    12661 tcaattccgt cgggaatatc ggtcagatga gcacgtttct ttaggaggcg cgagcggtgc
    12721 gcggcgcttg gtccggtgga gagaacgggt gttgagtctg gcccgttgcg ggagaggacg
    12781 agtcgagtaa ggcacgcacc gtgcgtaaca gaatatccgg ggtgaacggt ttttgtaaaa
    12841 acgtggttcg atggggatcc ataccgctgt tgacgcagat atcgtcgaga tacccggaca
    12901 tgaacagcac tcgcaggttc ggcttgatga cggagaggtg ctgcgcgagc tcgcggccgt
    12961 tcatgcccgg catgaccaca tcggttagca agagatcgac atgatagctt tgctgcgtgg
    13021 cggtcaggca ggcttcgacg ccattcttcg cttcaatcac ttgatacccg gttttgacca
    13081 attcatgacg aatcaagtcg cgcacgccgc cgtcatcttc gactagcagg atcgtctccg
    13141 atccttcgcg tggccggctt tggggtttct ccgaacgagc ggcagaggtc tgcggatttg
    13201 cgcgcgggaa atacaagtcg aaggtggtgc cgtgtccgac ctgactccag acatcgatgc
    13261 cgcccccgca ggtggtgacg atcccgaaga cggtggacag cccgaggccc gtgcccttgt
    13321 gttcttcttt cgtcgtaaaa aacggttcga ataagtgggc gaggacctcg gcatccatgc
    13381 cgcagccggt gtcggtgacc gtgagtttga cgtagtgtcc caacggcaag ggatggagat
    13441 gatgcatggg cgtgcgcgcc agttccgttt gcgatgtttc aatcgccagc aggcccccgt
    13501 tgggcattgc atcccgggca ttcacgacca aattcatgag cacttgttcc agttgccccg
    13561 gatcggcctt gacatggccg tgatgcgggt cgggacggat gaccaattga atatcttcgc
    13621 caatgagacg acggagcatg ccctctacat tggccaggat ggcatttaat gggagcacct
    13681 gcggttctac tggctgcttg cggctgaagg ccatgagttg gcgaattaaa ctcgcggctc
    13741 gctctccggc tttctgcatc tcttcgatct ttacacgaat tgggttgccg gcgggcagtt
    13801 ccccgaggag cacttggctg tgtcccatga tgaccgtcag gaggttgttg aagtcgtgag
    13861 ccagtcctcc tgcaaggcgg ccgacggcct ccattttctg cgcctgccga aactgttttt
    13921 cgctcatgcg caacgcgtct tcggcccgtc tccgttcaag acgctcgtca agttcacgca
    13981 gggtccgttt gatggatggg acaagtctgc ccaggcgttg tttaaagata tagtccgtcg
    14041 ccccgcgctg catcatatcg atggcgaatt cttccccctg cgttgcggag acgaagagga
    14101 acggcacatc cggatgcagg gttcgtgcga gaccgagcgc cgcggcgccg tcgaaaccgg
    14161 gaacggtggt gtcggcaaga atgaggctga agctttcctg gcggagggct gcgagaaagt
    14221 cttcacgcgt gtgaacgcgc ttcggttggc acagaatacc cgcctcccgg agcgtggagt
    14281 cgatcagatc cgcgtccgcc gggttgctct caagatggat gaatcgcagg ggctgagtca
    14341 tcatctgcaa cgagatcgga attagctgga ccggccggcg gaccggctgg ctccttcggg
    14401 cggtggttcg ttgatcatgc cccagaacac gcccagttct ttgacggctt tcagaaactg
    14461 atgaaactca accggcttga cgacataggc gttggctccg agtgcataac tctcagccaa
    14521 atcgcgttct tcgcgtgagg aggtgagcat cacgacgggg atcggcctga gggccgcatc
    14581 gttcttgatc gtgcgcagga cctcaaggcc atcgaccttg ggcattttca aatcgagaag
    14641 cacgacggcc ggattgcctt ggagacgcgt tttgaaatgg ccgcggcaat agaggtagtc
    14701 cagcacttcg gcgccatcat ggcacaggat gaccttatcg gccaaatgat gctcttccat
    14761 cgcagccagc gccagttcgg catcgcgcgg attgtcttca gcgagcaaaa tgggtttaga
    14821 agcgatcatg ccaagggcct cactctcggg aggctgacgt aaaaggtggc accttcgccg
    14881 agcgcacctt ccgcccaggt tttcccccca tgtcgatgaa taattcgcct gacattggcc
    14941 aatccaatgc ctgtcccttc gaactcatcc gctcgatgga gccgttgaaa caccccaaag
    15001 agcttgttgg cgtaacgcat atcgaatcct accccattat cacgtacgaa taacaccgct
    15061 tcatccgggc cgttgtccag actgccgatt tcgatcgtgg cctgtggcct ggtcccggta
    15121 aatttaatcg cgttcgtcat cagattcatg aaaacctgcc gcaacatggc ggcatctccc
    15181 gtgacctcag ggagttgagc gattgtccat gagattgcgc gatcttgcaa gtcatgtcga
    15241 agatcgtgcc gcaatgcggc gattaattgg ttcaaattga ctgtcccccg caacatttcc
    15301 tgccgcccca tgcgcgaaaa caccaggaga tcgtcaatga gttgtcccat tcgggtggcg
    15361 gattccgaaa tcgtctgtaa gtagcgtttc gccttatcgt cgagtgagat agacgcggct
    15421 ttcgcgagca gcgaggcata gccgtcaatg tgccggagtg gcgcgcgcaa gtcgtgcgac
    15481 accgaatagc tgaacgcctc cagttcctta ttggcggctt caagaagttc tccccggcgg
    15541 tggagttcgt cggcaatccg gcgccgttcg gtaatatcgt gccggatcag gtaatacacg
    15601 gccgcgagga gcacgaacag caagagcgcc ccaatggtca acagaatgat gctggagcga
    15661 gtcgtggttg ttgattcaac gacccgttgg gtcaaggctt tcgtctcctc ctgatccatc
    15721 tgcgcttgca gtcgtctcgc tgaatcgagt gcggtcttgg cgacccccgt gagcgccatt
    15781 ccccgcaccg agtcaaaccc tgtcttggcg cggagttcga tggcggcatg ttcttcttgg
    15841 agctgttgat tgatcaaatg ttcgagatca ctgacatgcc cacgctgtgt gctgcctgga
    15901 tcggtgagct cccgcaaata gcgaatatat tcgggcgcgc ggtcccgcaa ggtgttgtag
    15961 gcggccagat aactctcgtc tcccgtgacg agaaatcgac ggtgcccgtt ctcagcgtcg
    16021 tcaatcgctt ctccggttgc tccgagaaac tggatgaact cgtgacttcg cttgtctaaa
    16081 tcgccattcc gaatgaggac cgtcatgttg cgataggaaa tggcggaaat gaccaggatg
    16141 ccggcaaaaa ccaacccgaa tccagccagg acgcgctgtt cgatagatcg cttctgaaac
    16201 gtgtgaagca gtggcgagag gaacgatact cggccggaac ttttttcttc cgccggcgag
    16261 gcaggaggaa atgcggagtc gagcccgacg tcaacgggtt gatggcggtt tggttcgttc
    16321 atgcctgcag tgaaagctcc gagatctggg gactggagcc tgggaattgc gcgtcaatga
    16381 tgttgacgca gtcggaagac tgcacagcac attgtaccag aaggtactga tatgcgaaga
    16441 gaattgatgg aagccgagaa aagcgaagcc ggacgaatcc tcagcccccg aacggggtga
    16501 ccggcggagt cagggaagca gcgggtccaa tgagattgga aaacatcagc gtagctgcta
    16561 cagcccaatc gagaaacggt tgggggtaga tgccgattac gagcgtcccg gccaggccga
    16621 catagatcac tgctcgcagc ggacccgtgg tcttgatggg agaggagtcg agcggttcgt
    16681 tgatgtacat cttcttgacg acgatcagat agtagtacat cgagacaacg atgttgacga
    16741 ggccgacggt aatgagaatg tagaggcctt ctttgatggc ggcgacaaag atatagagtt
    16801 tcccgataaa gccggcgagt ggcggaaccc ctgcgagtga gagcaggaaa attaacatgg
    16861 caaacgccag aaagggcgag cgacggttga gtccgcgata atcgtcgatc tcatcactgc
    16921 ccacggagtt gctgatcgcc atgatgaccg caaaggcgcc gaggtttgcg aagagatagg
    16981 tcaacaggta gaacaagatt gagtcagtgc ccatcttggt tcctgcggcc agaccgatca
    17041 ggacatttcc gacctgcgcg ataccggaat aggccagcag gcgcttaatg tttcgttggg
    17101 cgattgccac gatattgccg tacgtcatcg atagaataga tgcggcgacg atgagcaagg
    17161 cccacgcggg cttaaacgtg gccagcgcga caaggaacaa ccgaagcagg atggcgaagg
    17221 ccgcgacttt cggggcgatg gacaggaacg ccgtcacagg ggtcggtgcg ccgtgatacg
    17281 tatcggggat ccaggaatgg aagggaacgg cgccgatttt gaatcctaat gccgcaaaga
    17341 tcagcaggaa gccgatgact aatcccgtcg tcgggttcgc gccactcatg tcggagaaga
    17401 cgagcttgcc ggtttcgccg tagacgaggc tgatgccgta cgccagcaat cctgccgcaa
    17461 agactccgag gataaagaat ttgaggccgg cctcgttcga cgccatgtcg tctcgcagat
    17521 aggagaccag cacgtaaaag ccgaaggtcg caaactcgag ggtgacgaag agcgataaga
    17581 gatcattggc cgaggccatg aacatcatgc ctaacgccga catcgcgacg aggaaataat
    17641 attcgcctcg aaagagcgag aagcgatgca catagtcgat cgaaagcaga atgaccagga
    17701 tcgtggccag gaggatcatg actttgaaga agatcgccat gcgatcgacg acgaacatct
    17761 tcccgaacag ggtgccggtg atgccggtca tgtcgaacca tgcgaggcag gccagggtga
    17821 taatcactcc caagatggtc aggtaggcca attgttcctg gacgatgcgt ttgaacgaaa
    17881 aatccacggc caggacgacg cacagccaga gcgtgagaaa cagttcggga agcaggagga
    17941 gaagatcgct ggctgaaagc gtcagggaga aagtcatcgc gaggttacct tcgcaatcgc
    18001 ctcaccggga acaggcacgg gcatggtgtg cgagctggct tgtggaatgt tcatcggaag
    18061 ctctgcgacc gggaccactt tggtaatacg cgcgatcagc gggtcgaccc ctgatcggac
    18121 cacggagtag agatgtcccg ggaaaatgcc gaagctgatg ctcaccgtaa tcataatgag
    18181 caggggcatg cgatcgacca ctgccacggc gtcgtgcgag tggctatact tttcggccat
    18241 cgaaccgtag aagaggccgc gcatcatctt gaagaggtag gccatggtca acacgatgcc
    18301 gagcactgcc acgacgactt ggaaagggta tttattccag ctgccgacga tgatcatcac
    18361 ttcagcgata aagttgacgg tcccgggcat tccgatcgag gccatgcaac cgatgacgaa
    18421 ggccgcagag ataaacggca tccggttgga gagccctccc agggacggga tgtctcgagt
    18481 gtgtgtttga tcgtagaccc agccggccat ggcgaacagc atgccggtgg ccatggcatg
    18541 cgcgaacatg tagatgacgg ctccgctgag gctgatgtag tccaaggccg ccatgcccaa
    18601 gaagacatag cccatatgac ttgagcttga ataaccgatg acgtatttcg tgtccttcgc
    18661 atagtacgcc accagcccgc cataaataat gctgaagata cagagcaccg cggcgatggg
    18721 catcagttct cgggtggtct ctggaagaat ttcgaacgcc acgcgaatga tcgaaaagtg
    18781 gccgagtttc atcagcacgc cggcatgcaa catgctggta gcggccgggg cggcggcgtg
    18841 acctaccgga gaccaggaat gcaatggcca gatcggcgcg atggacgcaa agccgaagaa
    18901 aatcaggagc cagatgagcg tggccaacgg ccctgagaaa tgggctttct cgcgcaagat
    18961 caggatatcg aacgtgttca gtccggaaaa tttgtagatg agcagaatcc ccatcaaggc
    19021 ggccacggca aaggcggaaa gaaacaggac cagcttcatc gccgcatatt ctttgctgtt
    19081 tgcgccgaag ttgaagataa agccgacgga gtcacgttgt ttcaggcctt cggggtccgt
    19141 catttcaagg tatttcttgg tatgactgcc ccacatgccc aaaagtaggt acatggggat
    19201 gacggacatt tcatagaaga agtacaggaa gaataagtcg agcgacatga agacgccgat
    19261 ggtcgcggca gcgagaatca ggatccagat gtagaactct ttcatccggt ctttgatatg
    19321 ccaggagacg aagatgccgg cgaacaacaa aatgcctgag gcaagcacca gcggagtgcc
    19381 aatgccatcg acgccgagat gcagggaaat gccgagctgt cgggaccact caatccgctg
    19441 gatgaactga tagccgccct tcactgaatc ataggcataa aagagataga cggaggcggc
    19501 caacgagaca aacgccgaac cggcggcaat gcctcgtacc agcgaaactt gacggttgga
    19561 gacgaaaatt aatcccaggg ctcccaggaa gggcgcgaac aaaatgatga gcagcgtgta
    19621 ttcagccata tcttacttcg ctggcacgtg gataacagtg tctactgagg ccactttcgc
    19681 acgatcaagt cggtcgacga gtgcttgaat ggatccattc atcattctga ggaagggcga
    19741 gggatagagg ccgatccaca aaatcataat ggagagcgag agggcaatgg tgatctcacg
    19801 catgtggaga tccttgacgg ccgccgacac gtgtttgctg agcgggccga gcatggctcg
    19861 ctcgtaatac cacagaaaat acgcagctcc aaagatcacg ccgagtacgg ccacggcccc
    19921 gaaccaccat ttcgctttga aggcacccaa aagaatcaag aattccccga cgaatccgtt
    19981 ggtgccaggc agtccgatcg acgccatgcc gatcaaaaga aggaaggtcg ccaggagcgg
    20041 agcctgcttg gcaaaacctc cgaaggacga taagtgcgag ctctgttggc gggttgacag
    20101 gaacccggcc atgaaaaaga ggccggccgt gctgaacccc agattgatca tggtcaacag
    20161 gctgccctgg agtccctgga aattcaacgc aaagaggccc accaccacaa atccgaggtg
    20221 actgatactg ctaaatgcga gtaatcgttt gaaatctgat tgcaccagcg ccacgaccgc
    20281 cccatagaga atggcagaca gggctaatac catgacgatg ccaaccactc cttcgctttt
    20341 tgatgcatcg ggcactaatg ggaaggtgaa gcggaggaat ccataggtgc ccaatttcat
    20401 gccggccaac atgacggcca tgccgatcgg accttcgacg agggcatcag gaagccaggt
    20461 gtgaaatggg aacaccggcg ctttgaacgc aaaccccata aacatgagcc agaagatcaa
    20521 aatctgctgc gagagtggaa tgggaacgga gagcagctca agcaggtcga atgaatacac
    20581 gtgatccatg tgatgactca cggcccactg gtgatagtta atgtcgagca aggcaatgcc
    20641 gaccaacata aagacgctgc ccagaagtgt atagagaacg tatttcaaag ctgcgtaatg
    20701 gcggtcggct cctccccccc acagcttgat caggaagtag ctgggaatga gcatgagttc
    20761 ccagaacacg aagaagagga ttagatcgat agagacaaaa atgccgatcg tggtggtttc
    20821 aagggccagg agggccatga aatagaggcg cacctgatta cggatcgtgt cccaggaata
    20881 gatcactacc aagaccgtca gaaaggccgt caaccccacg aagagcacgc tgatgccgtc
    20941 gacggcgagg tgatatccga ttcccagcgc cggcatccac cgggcgtgtt cggcgaactg
    21001 catggccgcc gaatcaggga caaaacgcac gaggacgagg caggcgagcg ccagttcgac
    21061 gagggtaata cccaatgtcg tcgatttgag aagatcctca tcgtcaatca gccagagaac
    21121 cgccgccccg accaggggga ggaagatcag gtacgagagg atggggaacc cgaaactgaa
    21181 ctcttcaagc atcgtaaatc caaaaatctg ccgcgtcagc gtgctgaata acctgtcgaa
    21241 ccgcctccgg tccagatcaa caagatgagg tggacgagaa tgaatagtcc cgccacgatg
    21301 atagctgcat actgatgtac catgccggtt tgcaggcggc gccaggagcg tgccaagagg
    21361 tgattcgcat agccgataat attgaggccg gcatagacca cgtgtttttc cgtccaggta
    21421 atcgccgcag agctgaggtc ggtgcctcgg tcaatgccgc ggacaagtcc gtcaataatg
    21481 gtgcggtcga accaatcgca gaggcggccc aattgtttgg tgggttccac gaacagggtg
    21541 tcgtagagct catcgacata gtacttgttg agcaaggtgg tatatgcgcc gggcatgcgg
    21601 tcggcaaggg ctgcggcggc ggttgatggg ccgctataga agtagtgtgc gaggccccat
    21661 ccgagcagcg cgatgacggt cgccgtcccc atgagcccaa acatcaatgc tggcggcgtc
    21721 gcatgctcct cacccgcgac tcctgccacg gaatggagga aatggtgaaa ccagccgttt
    21781 tccggtggaa cgccaggaaa cccgccgatg acggacaacg tggccagcac gacgagaggg
    21841 ccgatcatga ccatgggcga ttcgtgcacg tgttcggccg tatgatgatc gagtcgcgac
    21901 gttccataaa atgtcagata cgtcaggcgg aacatgtaaa acgacgtgag gaaggcgccg
    21961 actgctgcca tgccgtacag gagatagtga tgatggacga aggcatggcc catgatttcg
    22021 tctttgctcc agaaccccgc caaaggcgga attcccgcga tcgcgatcgt gccgatcagg
    22081 aacaatgtat gggtccatgg aattttcgac ttcaaggcgc ccatcttgcg gatatcctgc
    22141 tcgcctgaaa gagcatggat gaccgaaccg gctgacaaaa agaggagggc tttaaagaag
    22201 gcgtgggtca taagatggaa tacggcggct gtgtaggcgc cgagaccgca accaaggaac
    22261 atgtaaccga gttggctcac agtggaatag gccaggacac gcttgatgtc ggtctgcact
    22321 aggccgatgg tggcggcgaa aagagccgtc aatccgccga tccaggcgac ggtcgtcatc
    22381 gccatcggcg ccaggtcgaa aatggcgtga ttccgaacga tcatgtacac gccggccgtc
    22441 accatcgtgg cggcatggat gagcgcgctg acaggggtgg gaccttccat tgcatcgggc
    22501 agccaggtgt agagtggcaa ttgggctgat ttgccgacgg ctcccacgag gaggcagagc
    22561 gcgatcgccg tggccatttc aggcgacagc tgcgccgcgt tttgcatcac ctgcgtgtaa
    22621 tcgagtgtcc ggaagttcac gaagacaagg aaaatggcca gcaaaaagcc tgcatcgccg
    22681 atgcgattga ccacaaacgc cttggtcgcc gctttggccg ccgatacctt gtcgtagtag
    22741 tagccgatca acagatacga acagaggccg acgccttccc acccgatgaa caggaccaca
    22801 tagttgttgc ccatgaccag caggagcatc gacaccatga agaggttcat gtacacgaaa
    22861 aaccgtgtga agccggcttc tccatgcatg taccccacgg agtacacatg gatgaggaat
    22921 cctactccgg tgatgacgag cagcatgatg caggttaggg ggtcaatcag ataggcgaga
    22981 ttaatcgtga gatcgccgcc gaagatccat ttataggcaa tgacttcgcg agccgctccg
    23041 gtacgtaagg tttccgtgaa gactgccagc acgcagagga acgacatgag gaccgaaccc
    23101 catgcaaagc ggtgagccag gtcgtgagaa taacgatgcc cgaagagacc gttcacaata
    23161 acggccatca gcggaaacag gggaatcagt tttacgatca ggtcaatgga gtcggacacg
    23221 ttaccacttc aataggttca tttcgtcgac gttcgtcgag atcttgccgc ggaatacgac
    23281 aataataatg gcgagtccga tggcggcctc tcccgctgcg atggcgatga taaacaacgc
    23341 cacgatctga ccttgcatgg attcgaggta gtgagaaaag gcgaccaggt tgatcgtggc
    23401 cgcattcagc ataatttcga cggacatcag cacgataata aagttgcggc ggatgagaac
    23461 cccgagcaaa cccgtcgtaa agagaatggc actgacggcg acgtaggcgg ataaaggaat
    23521 catgcgtccc gccttgtttc gatagatttg ggcgccttcg ccagaacgat cgcgccgacg
    23581 atcgcgcctg tcaggaacac gccgataatt tcgaactgaa gcaaataatc gctgaacatc
    23641 ttgatgccta ccgcatgcgc atctccgttc aacagaacgg ctgccgtaga tgcatcacct
    23701 cgagatccgc taaacgggga acggatgagt aggaacagca ggtagatcaa cccgatgaca
    23761 gccggagcca ggagatacgg agttctcgca tggaaatagc ggtcgtcagt tttgaggttc
    23821 aatagcatga gcacaaagag gtagagaacc agaatggcgc ctgcgtagac gatgacttga
    23881 acggcccaca ggaactcggc gttcagcatc acaaacagcc ctgatacatg gagcaacaga
    23941 gccagaagcg ccaaaccgca ttgcacagga ttcttcaacg ccacggtgag aatgccggcg
    24001 acaatactga ccactgcgaa atacgcgaaa aacacgaaag ccataacggt acgattcagc
    24061 tcaaatgttt gggttgcgac tgtgtgggct ttagcacgga ctgcggaaag tagtaacgat
    24121 actcccggct ctcgtccgaa ttcttttctt gattatgggt atacaaatat tttttagcgt
    24181 cctcgaggtg gcgttcacca acctcgtaga gccgtttctt atcgaagagg agggtccgct
    24241 tgtcgtgggt ggaatattca tacattttcg tcatcgccag tgcgttgacc ggacaggctt
    24301 cgacgcagta tccgcaaaag acgcacttgg tgatgtcgat ataaaactca ctggcaaatc
    24361 gctgcagcgg tcgttcggga tcttcctggc tgatcacctt gatgcagcga gagggacagg
    24421 ccgcttcaca gagatcgcat ccgacgcagc gatcacgtcc gtcgctatag cgaaggaggc
    24481 caagagcacc ccgatggccg tccggaatgg tgcgctgctc acgcggatac tggaacgtaa
    24541 tagggcgatg gaacatgtgc ttgaaggtga ccttcatggc gtcccagatt tcatagaaca
    24601 acgccgcctg cagaactttt ttggtcaacg ccccgacact cattcccacc acctttgacg
    24661 acatcaaaaa gacggacgag cttactctta cgcaccaacc ttttcaatct ttacacgcgt
    24721 tgatttgaaa tacggcacgc cggttacagc atcgacttca gtcgtcatca aatcttttat
    24781 tggaggctca ttaaaatgtt cggggaaaaa gcacgatccg gattggacat ccgggtctgc
    24841 tttcactccg gcctgcacgg atgcttgctg cgagctcagg cggacagtgg attgctcggt
    24901 caggccgagt ttctccacat cagccggatt cattcgtata cgcccattat tgggctcaat
    24961 attaatgagc cctgacgcct gcgtggacat tttcccggaa tggtagagga cctgtcccat
    25021 cacgagggta aatggccgtg aggtgtcgtc catggcctgc cgtctgcgat accgggtgac
    25081 aacctcgctg gaatagccat tagagaggta tgcgtcagcg gagggagcaa tacggcgtgg
    25141 ttgccccaag ttgtagtagc cagggagcag cttcataatt tcgttctgca catcctgcgg
    25201 tgattgatag ggccattcgt agccgaggcc attggctaag gccgtcatga tatgccaatc
    25261 cggcaagctt tctccgacct ggtcaagcgc ctggcggaca cgcagaactt ttccttccag
    25321 attggtgaat gttccgtctt tttccgcata ggtagccgcg gggaggacga catgagccat
    25381 gcggcctgtt tccgtgagaa acgggtcctg aacaatcagg agttgcaact tgtcgagggc
    25441 ccccttcaca tccatggagg cgggcaaggt tgccaacggg ttttccccaa tgacatacag
    25501 tgccttgatt tggcctttct gaatgcgggt gaaaatctcc agaagattgg cgcccgtgcc
    25561 gatcgccgga agggtcactt cccaagcctt cccgaaacgt tctcgagccc cgggatcgtc
    25621 gaagcgggcc tgccccggaa ggaactctgg agcaacaccc atgtcgatgg caccctgttc
    25681 gttcacctct tcggtgacgg tagtgacacc gcatcctggt tgtcccaatt tgccggtcac
    25741 ccatgccagg tcaacgagct tgaggacatt ctcgtatccg ttgggacggc ggacaatccc
    25801 ttccgcgcac aaagccacgg cccgcggcgc ttccgcaaaa atggcagcca cctcgcggat
    25861 ctggtccact gagatcccgg tcgtccggga tacctcgtcc agggatattt gagcgactgc
    25921 ttgtttcaag gctgcaaatg cctgcgggtg ttgtgtcgta ctggtttcat cgaccagatc
    25981 ctgctcgatg acggctttga cgagaccatc aatgagcagt gcttcggtac ccggcttcac
    26041 caggagtgga tgcgatgcca attgggcgat attcgtgttc gatgaatcca cgacgatcac
    26101 ttgggcgtga tacacacgga tggcttcttt aatgcggacc gcggtcaggg ggttggtttc
    26161 tgtaatattg gaaccgatga cgaggacggc cttggccttg gtcagatctt cccaatcatt
    26221 gagcggtcgg ccaatcccga cggcatgtcg gacggcgtgc acgtagttta agtggccgta
    26281 tcgggcgcta ctgtcgagtt gattggtcct gaggccgcca cgcatgagct tctgaaacaa
    26341 gtagagttct tcgttggtgc agcgggcagt aatgagtccg gcgatcgatt ccgggccgtg
    26401 cttgcggtgg atgtctgaca actgatcgat gacggtctgc atcgcatcga gccatggcgt
    26461 ctctttcaga gtgtcgccgg tgcgaaccag gggttgccgg agtcgttgct gactgtcgat
    26521 gtattgaaat ccgaatcggc cccgaacgca cagtccgccg tgccccttgg cggtttcaga
    26581 ccggtcgccc catttgtttt tccaggaaag cggcgacgtc acgcgaacga cttccgtgtc
    26641 ctttgtttcg aggtgcattt ggcaaccatc gccacaatag ttacacgtcg tcgtggtctt
    26701 tctcatctgc cacggcttgt agagatattt cgagtactta ttcgtgatgg cgccgacggg
    26761 acacacggcc aagcaatccc cgcagaattc acaggcgagt ggctggtctc ctttggcgac
    26821 aacctggttg aaaccgccct tcttcatgaa ttgcagcgcg tcgatcatca acacgtcttt
    26881 gcagacgttg atgcattccg cacaggcgat gcagcggttc atgttgaagt ccagcaccag
    26941 gctacgggtg tcttctggaa tgaacttttg tttggcgttg gccaggttcg tgacgccatg
    27001 ctggaatgcc atgtcctgga gttcgcagtg cccgtccgcg tcacagacgg gacaatccag
    27061 cgggtgaact gaaagatgtt tctcaaccgc tttctttcgg gcggcgaaga ggtcatcacc
    27121 gtcggtccgg atcaccatgc cggctgccgc tttcgccgtg caggatcgta ccggcgcctt
    27181 cttcccttcc tgcatgacaa ggcacatgcc gcacgatccg aacggatcaa acgtgtagtg
    27241 gtagcacatg gccggaataa tcttgccggt gctggcgatc acatcgtaaa gcgaaacgcc
    27301 gtccttggcc gataccgttc gtccgtcaat cgacagttca atggtcgcgg cttcaacgtc
    27361 cggattagtc gctggtttca aacccatgct ttggcctagt acttagttat aagtgtttgg
    27421 aggggactga gaagttcaca cttctttcac ccacctctca atgtgcttat ctgtcacact
    27481 ctcccatgac gatgtcgtat gttccgaaaa tcgtcacggc gtcggagatc atatagcctt
    27541 tcgacatatg atcgaatgcc cccatatgaa taaacgaggg ggcgcggatt ttcagtcggt
    27601 acggcttccc gccgcccgtg ctgacgatgt agaaacccaa ctcaccctta tgcgcttcgg
    27661 tcccgcagta gatttctccg ggaggtgcat tgaacccctg tgagaacagc ttgaattgct
    27721 gaatcatgga ttccaggttc gtgaacacgc gctctttggg aggcagcgtc acgctgggta
    27781 catccgccat aatgggccca tcctggatct gttcgagaca ctggcggatg atcttgacgc
    27841 tctcgtagag ctcttgcacg cggatccagt accgatcata cgtgtcgccg ttcttgccga
    27901 cagggacgct gaattcacac ttgggatagg cagaataggg ttcgtatttg cgaaggtcga
    27961 aatcaacgcc ggaccctctc aacgttggtc cgctcaagcc aaagctcaat gcatcttcag
    28021 ctgaaatcac ggcgacgccc ttcgtgcgtg ccagccagat acgattcttc tcaaggaaaa
    28081 tgacgtattc atcgatcttc ggtgggaagt aatcgaggaa ttgcttcaat ttggcaaaca
    28141 gagacggggt gaagtcgcgc tcgacaccgc cgatgcggta ccagctggtc gtcaggcggg
    28201 caccacagag ctcatcgaac caatccaaca gaatttcccg atcacggaag cagtaaaaaa
    28261 atacggtcat cgccccgata tcaagggctt gcgtgccaag ccagaactgg tgaccgatga
    28321 tacgttgaat ctccgcgacg atcgtacgca ggtactcagc acgatccggc acggtgatgt
    28381 tcatcaattt ttcaaccgcg cggcagtagg cgaagttgtt gtacatcgcg cagacatagt
    28441 cgagccgatc ggtatgaggg atgaattggt gatacgtccc ttcttcggcg agcttttcca
    28501 cgccacggtg gagaaaaccc ataaccggag tcgacttgac caaccgctcc ccttccaact
    28561 ccagaatcac cttcaacact ccatgggtgc tggggtgttg agggcccata ttgagcagga
    28621 gttcctcggt cctgagcgtt ggaagcgttt cgctctccgg atgctcggga tcaattttat
    28681 aaacggtagt tctttgatct tcgaactgtg ccatggtcgt tcagtggggc taaacctgtt
    28741 gcctatcggg tcggttcatc caaaaactca aacgtgtctc gccaaccctt gccacgaagc
    28801 ggaaaatctt tacgcaacgg atatccctcg tcgtattcgt ccggcatcag aatgcgtcga
    28861 agatccggat ggttacggaa ccggatgccc atcatgtcat agacttcgcg ttccataaaa
    28921 tcggcgcctt tccagacgtc ggtcagggaa tcgacgatgc aatcggattc cggtacgcga
    28981 gttttcagac gaatccgttg tcgtgtacga atcgagtaga cctcgtagac gacttcaaac
    29041 cgatcttcat cgtcgggcca gtctactgag ctgacatgga cgatgtagtc aaaccgtaat
    29101 gcaggatcgt cccgcagaaa cttggctaca tcgtgcaacg tctcaggctt caccgtcacg
    29161 gcgaggtccc cgcgccactc cactactttt gtgcaagcgc caggaaaggt gtcctcgata
    29221 cgttgggcta gttggctcat gaagtcgttc cgtccgtcag accttcagcg cgtccttcac
    29281 ttctttgggc tgggagagga agacgcgctt ctgcatgatc cgctcctgca acttcagaat
    29341 gccatcgaag agcgcttctg gggttggagg gcatcccggc acataaatgt ctaccggcac
    29401 gaatcggtca actccctgaa ccacactgta actgtcgtat atatttcctg acgttgcgca
    29461 ggagcccatg gcgatcacgt acttcggttc gggcatctgg tcataaattt tgcgaatgac
    29521 gggcgccatg cgccggcaga cggtacctgc gacgatcatc aggtcggatt gtcggggcga
    29581 ggcccggaag acccctgcgc cataacgatc catgtcatag cgtgatgaaa cagccgcgat
    29641 catttcgatt gcgcagcagg ccagaccgaa ggtcatcggc cataaggatc cttttctggc
    29701 ccaattcacg gctttttcaa ccgtgagggt gatgacatcg ggagagccgt ctttatcgtg
    29761 gccaccgagt tgaattaatc ccattccaat gctccttttc gccaggcgta gacataggcg
    29821 acgaggaaaa gcccgataaa gatcaacatc tcgatcaagc caatgaggcc gatcttatta
    29881 aacacaatgg cccaggggta aagaaagata acttccacgt cgaaaatcac gaacaacatc
    29941 gcgaagatat agtaacgcac gggaaacggc attctggcgt cagaaaaggg ttcagatccg
    30001 cactcatagg tggatagctt ctctggttca ggatacttcg gttgaacaaa atagctgata
    30061 atcagcgtgc cggcgccaaa cgccagtgcg atgaacacaa agacgagtac cgggaaatat
    30121 cgactgagat actctaagag gagctcggaa ccggccatta gctcgaacct caacgggttt
    30181 gagggcttat aaggctattt aagaggtcgg aatcttagcc cttgctcatt tttaatagca
    30241 agcgcacaaa ggacctaggg ctttagtccc gatagtccta gaaagtgaat actgtccagg
    30301 agttaggagc gcgcgtcgat tgtcacgctt cgcggggctt gcttgatgtc ttcttgcgcg
    30361 atgtcgctga aacatcgctg atcgaatgct cttgcgtgga ggcggtcttc atctggctgg
    30421 ccggagttct caaaccagcc ggaggagatc cggcgccgat atcccactca gatgccatga
    30481 gcgtcgatgg ttgaaccttg gttcggcggg gcatctgagt gttgatgcgt cgtttgtcca
    30541 ttgcgttggt cacccgctcg atagtggttc cgggacgtat tcggttccga tctcacgata
    30601 acatccagag tggcctgatt caaacccttg gcctgtgcgc ggtttcttga caaccctctg
    30661 ctctttgcta aggttgctac aggcaaccct cctaggtgtg atcaatatga ggacattatc
    30721 tatgcgcgcc agcctgacca tcctctcatg cagtctcatg gctgtaacgg ccatcccagt
    30781 gtacgctcag aatgcgcaaa gcgtgcgact gggtgaggca gccttgacct atgccgccgg
    30841 gtcgatcagg caagacatgc cgatcgaggg tgtcatcaat gtcattactg gcgacaatca
    30901 attgtccggg aatcgaatga tgttgggctg gtccgggacg gacacgctgt atctcaaact
    30961 gaaaatccca ggcgacgcgg cgctcggtga cctctacacc gtatatcggc ggtctcgcaa
    31021 ggtgttccat cccatcacca agcagtatct gggatatgtc atcaatcggg tcggtgttgt
    31081 gaaagtcgtg cagctggatc cggtgctcgt gggcgtgcag gttgttcggt cttacgcacc
    31141 actttcaccc ggtgatcccg tcatgcgctt tacgcctccg gccgcggagg aagtcagcga
    31201 gcctgtttct tcagggccag atgtggaagg gatgatcgtt gagttacagg ctgacaagca
    31261 tatgtcactc gtgtcgcagg gcaatgtggt gtacctcgac aaggggcgcg acgatggtct
    31321 ccggtccgga gactctatgg aggtgtttcg cacgggcggc ggcttgcccg agcgaaagat
    31381 cggcgaagtg agagtgcttg ccacggaacc tcatacggcc accgcggtct tgtccaaggc
    31441 ttcggcccgc gccctcgtcg gagatcgtct tcgttccaaa catggcgtgc ccgtcgaggc
    31501 catgcagcct gagagcggag agattgatcg tcaggcagca accgtacagc ctgtgatggt
    31561 ggcgaagacg gatgcttccg tccgtgaggc gaatggaggc cgtctgcccg ccacagggaa
    31621 aatcgaacgt actcgtggaa gtcggcgact caacctggac gatctggccg accagttgga
    31681 atacgagtcc ggggaagtca aagtgaagcc cgccggggta cccatccttg aaaaattgac
    31741 tgagtatttg accactacgg ccaccggtca gcaggttcgc gttgaaggtc attccgataa
    31801 catggaaatc ggcccgtcct tgaaaggcgt ctttcccacc aattgggaat tatcgaaggc
    31861 ccgggcggca gagatcgtcc ggtatttggt cgagaagggt ggaatggatt ctgcgaagct
    31921 gtctgccgtc ggatatggag ccagccggcc ggtggcgagc aacgggaccg aagagggacg
    31981 caagagaaac cgccgcattg aagtcgtact ggagtccctc gaagaggcgg ccccagcgca
    32041 accggtgaaa gcctcggttg atgaaacggc atcggtgtcg acacagttta cgtataacca
    32101 gatgaatgcc gtgccggtga atccgacgag cgtcccggtg tcggaggtgc cgtctggacc
    32161 ggctccctcg gatgtgacac ccgagcgtgg cccgatagcc cctgaggccg gagtgccggc
    32221 ttctcccgct gatgggatgc caccgtcgcc tgcccctggc tcctagtaga ggcggcggct
    32281 ggtctctcgc aagaggccgg ccgccgttca gtgccctctc tgtaaccttt ctccttatct
    32341 gatctcatta cctgttcggg ctcattcctc gcgcgagctg atcccggttg tcattgttgc
    32401 accgggccgg tgttgttaga atgccgcatg ctcgaccctc ctttgcagca gccaagtgcg
    32461 atgattccgg ctccttctcc tgcgtatgtt gatgtcgtat tgcctcgtcg gcttcatcga
    32521 ccgttcacct atatcatccc ctcagaactc aagggccgcg tcgccatcgg acgttcggtg
    32581 gtggtgccat ttggctcgca agaccttcac ggccttgtca ttgcggtgca tcatcggctt
    32641 ccacctggcg ccccacagaa gggcctcaaa gctattcgtt cgttgagtgc ggcctcagcg
    32701 gatcatctgc ttacggccgg ccaaatcggg ctcagccact gggttgcgga acggtatgcc
    32761 gcaccgtggg ggcaatgtat caagctcgtt ctgccccctg tcgatcgagt gggggcgtcc
    32821 cagccgcgat atatggcgac agcgcagggc cttgcgacga acgcgtccgt cgagccgttg
    32881 ggagaaaccg aaacagagtt gctcgcccgc ttacgccggc gtccccaggg catcatggcg
    32941 acgactcttc tgaagggcga caggtcccgc acgacccttg ccttgcaggc actgatccaa
    33001 aaggggctgg tgagtcgttg tgaagaacgg gccgcccaga aaagcgtccg tcctgcaaat
    33061 caacagagcc agttgtcagg gggcgggctt cctatggaat cggtggaggc tgttgagaat
    33121 ttggagctgc ctcatgcgga agccatgtcc tggtcagcgg ttctggaaca ggcattggca
    33181 aagaagacct tcgtctcctt gctcctggag ggtagccact gcaccagaca gtggtgtctg
    33241 gcgcaagcgg ttcgagccac ccttcgcctc gggaggcagg cgttgattct cacgggtgat
    33301 gtcgagcatg cgagtcgttt agctgattcc ctcgccgcag gaggcgaaca gccgatgctc
    33361 ctgcacagtg gtctatcgat gacagcgcgg gcggcggtct ggcaggcggc gcaagagggg
    33421 tcggtcagga ttctgattgg cacccgcatg gcggtcttcg ctcccctgag gcggctaggc
    33481 cttgtgtggg tggatggtga ggatgatgcg tctttcaaag aagagcaggt gccccggtat
    33541 catgcccgag aggtggctca ctatcgggct tcccgcgacg gcgcggtgct cgtgcttgcc
    33601 tcgaatcatc catctctcga gagtctgtcg gcggttcagg aaggacgcat gacggcatgt
    33661 aagtatcgcg atgcgggcga actgccggct gtgcacgtca tcgacatgaa ggagtatccc
    33721 agagacgcct caggagggac ggtgttatcg cctcctctta ccgaaggact acgtgaggcg
    33781 ttgcggcagc acgccttatc gatcctgtac ctgaatcgca aagggtttgc gagtgtgctg
    33841 cattgcgggg attgcggggc gatgccgcag tgtgatgcct gtagtgtcgc gctgacgttc
    33901 ttcaggcgaa gcaatcatgt ccggtgccac tactgcggtc gaaccaaacc tgtgcccgaa
    33961 cactgttccc gctgtcagtc gctcaagttg gaaccggtgg gatcagggac ggaacgtgtc
    34021 gaagaggccg tccgacgtct gttcccgcag gcccgggtcg gacgtgtgga tggcgaaacg
    34081 attcgtcgtc cagccgatgc acgggccttg aatcggttgt tggccgcagg ggaactcgat
    34141 gtcgtgatcg gaacccagat gatattccga cttggtctcg aggggcgggc gttgtgtgtc
    34201 gcgcttcccg acgcggatgc cggtctccac attcccgatt tccgttctgc ggagcggatg
    34261 tatcatgccc ttcgagatgc cgccgagctg gcccgtcccg cctctgaggg tggccggctt
    34321 ctcatacaaa cgcgcttggc agaccatcat gcgattatgg cgctgtcctg cggtgacgaa
    34381 gaggtgtttg tgaggcagga gcaggccttt cggcagatgc ttcagtatcc gccctggacc
    34441 cgcctggtca ggttagatgt gtccggaaca caggaggcca tggtatctca agccgccgat
    34501 cgctgggcgg cattgcttaa agcccaggcg gcaggcaggg aaccgatggt tgtggtcttg
    34561 ggcccatctc ccgcgccgca cgttctgagg cgcggtcggt actgctggca gattctgatc
    34621 aaatccgcgt ctctggaggc agggaaggag atagccgtgc gaacgcgtga ggacgtggag
    34681 cgggaatcac gccgtggtgg cctccg
//
LOCUS       DAOQPD010000036        34102 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_538_length_34102_cov_24.630217, whole genome shotgun sequence.
ACCESSION   DAOQPD010000036 DAOQPD010000000
VERSION     DAOQPD010000036.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 34102)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 34102)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34102
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_538_length_34102_cov_24.630217"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(2..76)
                     /locus_tag="PK063_10000"
     tRNA            complement(2..76)
                     /locus_tag="PK063_10000"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(42..44),aa:Gly,seq:gcc)
     gene            351..680
                     /locus_tag="PK063_10005"
     CDS             351..680
                     /locus_tag="PK063_10005"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97426.1"
                     /translation="MTSRPQQSAPFAAQAVSFDEYLASGKIPDGLLVSEYVEQQFVER
                     LVHYVLSVPAGSYSMAQLSRLLEQLDPRAQVFFFKRLKENSPDSLKDFAPLYYGFMNE
                     FHSLLFT"
     gene            764..1132
                     /locus_tag="PK063_10010"
     CDS             764..1132
                     /locus_tag="PK063_10010"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97427.1"
                     /translation="MNPTLQRAVTSFYNLVYEAQTFATTMSRIDTAEQEHYAGRIEGL
                     NWVLDRCQELEDMDANITPTTLQRVLTEVKSDLDHELSVQRREKGRRADGREEALTFV
                     ADYLSSLITATEIESAKTSV"
     gene            1190..1423
                     /locus_tag="PK063_10015"
     CDS             1190..1423
                     /locus_tag="PK063_10015"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97428.1"
                     /translation="MAREWIIFAICLGLGGHIALAVVLHAPDMWPWSKAWLYGLLSGL
                     TLYIVVQVLRSLWWVFRGRNGDEPDVPEDQHIR"
     gene            complement(1934..2230)
                     /locus_tag="PK063_10020"
     CDS             complement(1934..2230)
                     /locus_tag="PK063_10020"
                     /inference="COORDINATES: protein motif:HMM:NF015899.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trm112 family protein"
                     /protein_id="HMZ97429.1"
                     /translation="MRFIVSDAVQKKVNLDKDLLAILCCPETKQAVVLADDLLIQKVN
                     GAIERGVLKNKAQKAVTEKLDGGLVRSDNKILYPVREDIPVMLIDEGIPLDQVA"
     gene            2373..2999
                     /locus_tag="PK063_10025"
     CDS             2373..2999
                     /locus_tag="PK063_10025"
                     /inference="COORDINATES: protein motif:HMM:NF016270.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF502 domain-containing protein"
                     /protein_id="HMZ97430.1"
                     /translation="MTSSHRLGRIFFTGLLLLVPAWTTFLILAALFETLDSFLLNLIG
                     HQIQPYAPGLGILLLIGMVLMVGAIATQVIGQRFVRWAETTLEGIPLIRSIYLTLKSM
                     TDLLNYRARFGQSTVVAFPFPRDGLWALGFVMGPPPAALQVAPSVELVMVFVPTAIHP
                     FTGYLAMIPKTQLQPLNLLPEEALKLEFSAGLYRPLQGWLTAPAVKSS"
     gene            2996..3511
                     /locus_tag="PK063_10030"
     CDS             2996..3511
                     /locus_tag="PK063_10030"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF012792.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HMZ97431.1"
                     /translation="MISADQLRIRLATVQDVDVLTTFSAAMAWETEHRRLDLARLRLG
                     TQAVIDRPEQGQYYVADLHRNAPADTVTVGQLLLTYEWSDWRNAQFWWIQSVYVDPAW
                     RRQGVYRAMHQAVMALAQSRADVCGVRLYVEGDNTVAQGVYERVGLTPSTYRIYESDF
                     VLPKPSSPDRR"
     gene            3549..3929
                     /locus_tag="PK063_10035"
     CDS             3549..3929
                     /locus_tag="PK063_10035"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97432.1"
                     /translation="MRRAGLLLGAMLLTLNACAFSRGTLGEEIKTDTVNSIKKGVTTR
                     ADVLAQLGAPDRLLQLNGRDLFQYYRYDAKVGSLLLILINFSRVSVKSDDLFVIINRD
                     GIVEDVIASKRTENLEFRFWPFGD"
     gene            3982..4356
                     /locus_tag="PK063_10040"
     CDS             3982..4356
                     /locus_tag="PK063_10040"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97433.1"
                     /translation="MMPLSGCNVARLTINTPLTPQTVSFITEGQTTLTDVVNKLGAPD
                     SITDAEGGAVVTYRFLNAKYSRVNFGWLVKPWSPVDPDLVFSRSGMGTDAFELLCDSN
                     WVVTHQAFVRHRPDPLFTPYPF"
     gene            4422..5279
                     /locus_tag="PK063_10045"
     CDS             4422..5279
                     /locus_tag="PK063_10045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HMZ97434.1"
                     /translation="MGAGSSDESASRHPHSASSSYIPADRDIDFLQRDELRPLRLGLE
                     LLKPELIQIEQGIRSTIVVFGSSRLVEPSLARQALEAAKAELQIAPQDALRQQQVTMA
                     ERRLAMAHYYDIAREFGRLVSATCQINGQCDFVIVTGGGPGIMEAANRGAADAGAKSI
                     GLNITLPHEQQPNPYITPDLCFQFRYFALRKMHFLLRARALVVFPGGFGTLDELFETL
                     TLLQTGKTRNITIVLIGRAYWERLINWSMLADEGLIGPNDLALFHFAETAQQAWDLIS
                     QTHGGPAAR"
     gene            5276..6673
                     /locus_tag="PK063_10050"
     CDS             5276..6673
                     /locus_tag="PK063_10050"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024118.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HMZ97435.1"
                     /translation="MKISFHGAARSVTGSRHVLEMPGSRILLDCGLFQGPRQEADRQN
                     RFLGFDPRSIQAVLLSHAHIDHSGALPVLGQHRFRGDVHMTRATADLTAVMLEDSARL
                     QENDCAYLNRKEHRRGQKCLKPFYETRDARAIIRRFVGARYGDTIKVTPRLTASFHDV
                     GHILGSAAIRLKYSARGNSTTVLFSGDLGRSHMPILRDPTPPPSCDVLIIESTYGDRL
                     HEEAGETLTKKAQQLVAHAKAHNSKIIVPAFALGRTQDLVMRIKHLVAEGQIDPLPIY
                     IDSPLASKVTDVFRKHPECYDEETYRTFTSEGDPFAARYIRYVSSPDESKRLNSVKGP
                     CVIIASSGMCEGGRVVHHLKHAIQDEANIIAIVGFQAEHTLGRRLVEGWDVVPLFGIP
                     TARRAQVVVFNGLSAHADRNDLLAYVRAISPPPQHIFVVHGEEKQALSLAAAIQAEYP
                     RTSIVVPHKESSYEV"
     gene            6722..7987
                     /locus_tag="PK063_10055"
     CDS             6722..7987
                     /locus_tag="PK063_10055"
                     /inference="COORDINATES: protein motif:HMM:NF015535.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HMZ97436.1"
                     /translation="MSHSHPGSFSIIACVVLVMTTGVHSGWSAETLSDVTEEPRVRAR
                     ALGLTLGQLEPGPLNAITDVPGVKVGQVTLRRGEGPLQPGQGPVRTGVTVVVPREDVW
                     HKKVPAGAFVLNGTGEMTGLAWVAESGFLEYPIALTNTLNVPRVANGVISWMLRRYPG
                     IGITDDTLTPVVAECDDGRLNDIQGRHVSEADVMQALDDAASGPVSEGTVGAGTGMIS
                     YGFKGGIGTASRRLPAAAGGFTVGVLVNANHGRRPELMMGGVPVGQRYDAAPTQSGAL
                     LESNPERLHASREGSSGNAEGSIIIIVATDAPLDSRQLTRLGKRAALGLARTGSTARH
                     GSGDFMLAFSTGNVIPHYPTEPTFSLTHLADTHLNAVITATVEATEEAVLNALTGATT
                     VTGRDGFRAEAISLPRLRTLLSPDPAIGR"
     gene            8075..8302
                     /locus_tag="PK063_10060"
     CDS             8075..8302
                     /locus_tag="PK063_10060"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97437.1"
                     /translation="MADYSMGGGLTLLTALEKSDKFADFLKTRMAQALETRDPTELHY
                     LLAQLDDYHSYMWRYYKKLATERPERMNPGV"
     gene            8354..9574
                     /locus_tag="PK063_10065"
     CDS             8354..9574
                     /locus_tag="PK063_10065"
                     /inference="COORDINATES: protein motif:HMM:NF020084.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIST N-terminal domain-containing protein"
                     /protein_id="HMZ97438.1"
                     /translation="MTAPSTLRFASALTRHADAQAAAADLIHAIREQLGPSRIDVAFL
                     FISAQHADQAEALSEALRTALGPVTLVGCTGEGIIATGREIESGPAATLWAAHLPGVL
                     VQPLRLSFSSVHDQFSLRNWPDLDEVGDTAPVMMLFADPFSTPMQEVLSVIEEQYPGT
                     RTLGGLAGGGQDLGENRLFLDDQVLTDGLVGVALSGNIAVRSVISQGCRPIGDRFIVT
                     KSEHNVIQELGGMPALHCLQTVFEQLSSDERAQAQRALHIGIAMDEQRAQFTLGDFLI
                     RNLLGADQQTGAIVIGDVIQEGQTVQFQVRDAHSADEDLHALLAAPPQGVPSKPLGAL
                     LFSCCGRGKGLFGVPHHDASVLGEQLGAIPLAGFFAQGEVGPVGGRNFLHGYTASIAI
                     FSEPERGHQTGLNR"
     gene            9698..10072
                     /locus_tag="PK063_10070"
     CDS             9698..10072
                     /locus_tag="PK063_10070"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HMZ97439.1"
                     /translation="MMANSEQPGTTAEVTTASGLKYVDVVVGTGREAAAGNLATVHYT
                     GWLTNGKKFDSSVDRRDPFSFPIGAGQVIRGWDEGVAGMKVGGKRKLTIPPELGYGAR
                     GAGGVIPPNATLVFDVELLEVR"
     gene            10129..11238
                     /gene="gcvT"
                     /locus_tag="PK063_10075"
     CDS             10129..11238
                     /gene="gcvT"
                     /locus_tag="PK063_10075"
                     /EC_number="2.1.2.10"
                     /inference="COORDINATES: protein motif:HMM:NF001567.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004047 - aminomethyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system aminomethyltransferase
                     GcvT"
                     /protein_id="HMZ97440.1"
                     /translation="MKQTPLIDAHRNAQGKLVDFAGWEMPIQYSGVVDEYQTVRRHAG
                     LFDVSHMGRIRVAGPGSLAFLQRVTTNDVSKLSVRQSQYSMVCAPNGGIKDDIFIYHV
                     KPYEFLVCVNASNREKIVAWFHEKVAQAQGCTVQDQSTTLAQIAIQGPASRDILTAVG
                     LTDLPLLKIRHCLDAVVCGHATLVTRTGYTGELGYELYLPAEGAMKIWNRLLEAGHPL
                     GMKPAGLGARDLLRLEMAYLLYGNDMDEGTSPIEAGADWVVKFDKGEFIGRTPLLAQH
                     NDGPSRRLVAFELVEKAVPRHGFKILSTQDQHAVIGEVTSGNLSPLLQKGIGMGYVTP
                     AASQPGSSILIDIRGKSCPAVVVKPPFYKKQPSTP"
     gene            11251..11769
                     /locus_tag="PK063_10080"
     CDS             11251..11769
                     /locus_tag="PK063_10080"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HMZ97441.1"
                     /translation="MVRPIYKGTVVTLNVDTVRLPNGHTIDLEVIRHPGASAVVPLKK
                     DGTVVLIRQFRHAANGFIYEIPAGKLHPNEDPLDCAARELEEEIGYKAGRFQLLSSIF
                     TAPGFADEVIHVYLATELTLGTQNLDQDEVLDVVEMPLKEAIDRIEDGTIRDAKTIVG
                     LQAVYIRQVGNR"
     gene            complement(11846..12070)
                     /locus_tag="PK063_10085"
     CDS             complement(11846..12070)
                     /locus_tag="PK063_10085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97442.1"
                     /translation="MKKMMLTVMAAALLVAFSAPSFAGDDKKKEEKKGGHFSQTLFGD
                     DKKKEEKKGGHLSQTVFGEEKKKDEKKGGH"
     gene            12347..12877
                     /locus_tag="PK063_10090"
     CDS             12347..12877
                     /locus_tag="PK063_10090"
                     /EC_number="3.2.2.-"
                     /inference="COORDINATES: protein motif:HMM:NF015146.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008263 - pyrimidine-specific mismatch
                     base pair DNA N-glycosylase activity [Evidence IEA];
                     GO_process: GO:0006285 - base-excision repair, AP site
                     formation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mismatch-specific DNA-glycosylase"
                     /protein_id="HMZ97443.1"
                     /translation="MPLSLPDHLAPNLNILFVGINPGLRSAAVGHHYAGHSNRFWKLL
                     YDAALVPEPLTYHDDERLLEWGLGLTNLVARPTAGSEHLTAEDYATGRRALMEKLRRY
                     RPRVTALVGITLYPILFPLEPKQAGRKPGLQSVTLYDSSIVLLPNPSGRNAAYPYHAL
                     LDAFCTLTPWVRTSLG"
     gene            12984..13625
                     /locus_tag="PK063_10095"
     CDS             12984..13625
                     /locus_tag="PK063_10095"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97444.1"
                     /translation="MNYPVIALWGLLGVALIGEQAVAGTAVQRLTAESMHECSLGRQA
                     QTRADRIQHFASGQAFGEQAVAADESSPDAHFALFCNLGEQLRVDGESLSSLFGFRRM
                     MKELNRTLELDPSHLDALSAKGTVLVRVPGFMGGDKEKGELLLRQVIAREPAAVNARL
                     SLAKSYCADGRHEEAVAIATKALDLAQELQRADFIPEARQVLAQLRAQSTKGN"
     gene            complement(13622..14542)
                     /gene="rbsK"
                     /locus_tag="PK063_10100"
     CDS             complement(13622..14542)
                     /gene="rbsK"
                     /locus_tag="PK063_10100"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: protein motif:HMM:TIGR02152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0019303 - D-ribose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HMZ97445.1"
                     /translation="MVVVVGSSNIDFTAVVDRLPARGETLLGHRFLQSFGGKGANQAV
                     AAARAGADVAFLSKVGNDFNGDLIAQHLATQGLSRLMLLRDAAVQTGVAMILVDVAGD
                     NQIVVVPGSNQQLTPADVEQHAQLIADARVLLVQMEIPIDTVQQCLRLAKRYGLRTIL
                     NPAPACPLPPESLRMVDILTPNEREACVLSGATDPADAARVLVSTGAETVVVTRGTEG
                     AVVSRGKHVTHIPAFIVDAIDSTGAGDTFNGALACGLAEGLSIEEAVEMAAAAGALAT
                     TGYGAQAAMPARGDIDRLRRTGVRRMPPRG"
     gene            complement(14533..15525)
                     /locus_tag="PK063_10105"
     CDS             complement(14533..15525)
                     /locus_tag="PK063_10105"
                     /inference="COORDINATES: protein motif:HMM:NF013335.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HMZ97446.1"
                     /translation="MQKTSPTKVIIDTDPGVDDALAILLALASPELDVVGITTVCGNV
                     PVGQGTKNLFRLLNLLNPPPGLLVGQGAARPLEEALETAVHVHGSDGLGELDALLSAE
                     GTMRYPAVRLPPLLSTAQDVWNECVRRYQDDITLITLGPLTNVAVALKVNPLTVQKFR
                     SVIVMGGAIGVPGNVSPVAEFNMYVDPHAAHRVFQAALPLTLVPLDVTTRVGLRRDVL
                     KMWTGASRDPRCRIVADMTAKAFDFAEQVEGHGLLYFHDPMAVLAAIEPSLLKTEPLH
                     VEVEVVGRVSRGATVADRRHRRPEEKANPNMQVAVDVDAERALSVIRSRLCPWS"
     gene            complement(15602..16291)
                     /locus_tag="PK063_10110"
     CDS             complement(15602..16291)
                     /locus_tag="PK063_10110"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97447.1"
                     /translation="METATSFAPVRRWMPSRDSASGGGTWLTAVGRVRRVVRQIAIGC
                     LLLNMFFALPVHAAIESVAVEDTHIEDSPLDVVSGLTYRAGTRLRIPGTGWSFVVPDG
                     WQSNRPDDAEMPFLIPEEGKELGMMFPLAKVTRDALREQLREPLLLLHGLSFIPAGAQ
                     AETDAWIAQSYEGEGMAGRALAVMGADNTAVIYFLMGPPHNMSVLQSVLEQLGQSTRF
                     VQSTPRRDAGL"
     gene            complement(16239..19124)
                     /gene="gcvP"
                     /locus_tag="PK063_10115"
     CDS             complement(16239..19124)
                     /gene="gcvP"
                     /locus_tag="PK063_10115"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004375 - glycine dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase"
                     /protein_id="HMZ97448.1"
                     /translation="MPEPQFLEPNDTFVPRHIGPTESEIQTMLETVNVPSLDSLVEAT
                     VPSDIRLQGSLAVPSPRGEQEVLAELRGMAGQNQVWRSLIGMGYYDCITPPVIQRNIL
                     EGPGWYTQYTPYQAEIAQGRLEALVNFQTMVADLTGLPLANASLLDEATAAAEAMTMC
                     AAISRAAGHDRHKFFVSETCHPQTIAVVQTRAEPLGIVLQVGAIQSLDLSSGEFFGML
                     LQYPSTDGYVGDYSEFITRAHAAGVYVVVATDLLALTLLRPPGEFGADVAVGSSQRFG
                     VPLGFGGPHAAFMATKEEFRRQMPGRIIGVSKDVTGRPAYRLSLQTREQHIRREKATS
                     NICTAQVLLAVMAGMYAVYHGPAGLRRIAERIHGLTMALAEGLRRHGCAVGLEPVFDT
                     LRVPLSPAQSETIVNRARQQKINLRRYDDHSLGLSLDEWSTVDEVRQLLTLFAGQEIS
                     PEELQTILESVDGRYPAGLARTSQYLTHPVFHRYHAEHELLRYIHRLQSRDLSLVHSM
                     IPLGSCTMKLNATAEMLPVTWPEFGRLHPFAPADQVQGYLALFQQLESWLAEITGFAG
                     ISLQPNAGSQGEYAGLMVIRAYHRQRGETQRDICLIPVSAHGTNPASASMCGMTVVPV
                     ACDQRGNVDLADLEAKATQHRSRLAALMVTYPSTHGVFEEGIRRMCQIVHTHGGQVYM
                     DGANMNAQVGLCRPADLGADVCHLNLHKTFCIPHGGGGPGMGPIGVARHLMPFMPGHP
                     VTKLGGPQSIGPVSAAPYGSPSILTISWVYIALMGREGLTKATQVAILNANYMAKRLE
                     KFYPVLYSGARGFVAHEFILDLRPLKDSSGVEAMDVAKRLMDYGFHAPTVSFPVAGTL
                     MIEPTESEVKSELDRLCDALIAIRGEIQAIAEGRQPRAGNVLKNAPHTAMAVTASEWT
                     RPYSREEAAFPASWVRENKFWPSVGRIDEAYGDRHLFCTCPPVDAVS"
     gene            19332..20984
                     /locus_tag="PK063_10120"
     CDS             19332..20984
                     /locus_tag="PK063_10120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HMZ97449.1"
                     /translation="MTHDILVVGAGLAGMRAAIAVPPDLNVALLSKVHPIRSHSVAAQ
                     GGINAAIGAEDSWEAHAYDTAKGGLYLGDQDAIEAMCKEAPQDILELERMGVIFSRTA
                     EGRIAQRPFGGAGYPRTCYAADRTGHALLHAMYEQLMKRRCKVYEEWYVTALLVEEGR
                     CCGVVAWDMIHGGLQMLRAKAVILATGGSGRIFSTSTNAVINTGDGMALAYRVGIALE
                     DMEFVQFHPTTLKDTGILITEGARGEGGYLLNTLGERFMKRYAPEQMELATRSTVSLA
                     IGQEIQEGRGVDGCVLLDLRHLGRAKILERLPQIRELAMEFAGLDPIETPIPIRPGAH
                     YQMGGVRTNAWGETELPGLFAAGECACVSVHGANRLGGNSLLETIVFGRRTGTKAAES
                     IRTVQLSPVSETILKSEQQRIDKLLSNPGPERAWQIRDDLGKTMSLNLGIFRTKQSIQ
                     EALSAVQALKRRAEDMCVQDKGRVFNTDLIHALELQCLLEIAETIVVGALGREESRGA
                     HYRGDFPTRNDTAWLRHSLSYRRPEGPHLAYAPVTITRFPPA"
     gene            21160..22470
                     /locus_tag="PK063_10125"
     CDS             21160..22470
                     /locus_tag="PK063_10125"
                     /inference="COORDINATES: protein motif:HMM:NF024206.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ankyrin repeat domain-containing protein"
                     /protein_id="HMZ97450.1"
                     /translation="MTTVHPGTALPASPTLTASDAAQTAICPFCQAITSCAPVAGHRL
                     HQFPCPSCHANLLVLNPAARPTDEDKKTRSSDGDLPIDLSHRLTGIAVAVLACALNYV
                     LLMGMAYWILGQVKTTHDPYDIDALMLSPLILKANGWTPLHLAAARGDQSAVATLLTE
                     GQTVDQRNGNGRTALFEAAKRGQTDVVTLLLQHGANPSAKGKQGFTPLLAAAEQGHAD
                     TIEVLLTNGADIRATCTCGDSALHRAVRHGHLAAAQTLLEGGIPVNQKSHGETPLEIA
                     QHDEDHELIALLRAYGGREFSDAKAKRAEGIAFQKHGQIDHALFAYAEALNLDPDDHE
                     AYYGRGTALLQKNAPDEALIALHAAIRLNPTYLDAYSAAASVHTSRGQWDQALRLWDQ
                     LLSHQPQNGRAIFERSIVKRGKGDSAGFLQGLQQACALGHRAAC"
     gene            22723..23745
                     /locus_tag="PK063_10130"
     CDS             22723..23745
                     /locus_tag="PK063_10130"
                     /inference="COORDINATES: protein motif:HMM:NF017770.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjgN family protein"
                     /protein_id="HMZ97451.1"
                     /translation="MPAPMRASFHGMGGTLLGMHVVNVCLTLVTLGGYHFWAKAKIRR
                     YLFSHTAFAGDRFAYHGTGKELYQGFLKAMLVFGIPYFSLSAAHTFLELPQWIDVLLQ
                     VMAGLVFFLYVPVAIVNARRYRCTRTSWRGIRFSFRGRTSDFLKLYFRGWFFTILTLG
                     TYYPYFQTQRQAFLHSHTYFGNQRFRFTGHGSGVMVPFAITLFTTYAVLALCGFALAA
                     QLTNAGLTLLLIPCVLGPMWIWLLGQKQRYFWNHTSFGDAQFSSEITWQRLFTLYLGN
                     LGLLLATLGWAWPWVTVRNARFFMGTLSLQGPVDLDRVLQDTSEASVTGEGLSNLLDT
                     GFDMDA"
     gene            23748..24890
                     /locus_tag="PK063_10135"
     CDS             23748..24890
                     /locus_tag="PK063_10135"
                     /inference="COORDINATES: protein motif:HMM:NF013594.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HMZ97452.1"
                     /translation="MSTARTAHYLDGRTATRHRVTLTISPAALQIAMPDGSTKEWPYG
                     QIRQTQGTYRGEPVRLEFGTEPAEAVVVASRALLTDIHTAAPALAQHFHDPSWRQRRL
                     AWTLGAGLGVIVMLIGLYRWGIPGIASAATPYVPIMWEESLGRQIVEHLAPATQQCRE
                     PERLRKIDQVVQMLAATHPDSPYRITLSVVDNPAINAFAAPGGHVVVLRGLLEQTGSA
                     EQLAGVLAHELQHVYLRHSTRAILEQTAGTLLLTAVSGDLSGGLAWGLQGAQTMGSLH
                     YSRTHEEEADVEGLRMMQAAHLDPTAMIAFYGTLQKSEQDHIEPPDFLSTHPDMSRRL
                     ATLLALAGPPPTDARQLLPGEDWKDIRTLCRLQTATRSSSDSPDLP"
     gene            24959..25630
                     /locus_tag="PK063_10140"
     CDS             24959..25630
                     /locus_tag="PK063_10140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ97453.1"
                     /translation="MRVLVVEDETKVGSFIKRALEEESYAVDLCEDGAQGLDLALTGS
                     YDLIMIDLMLPGLPGMEVLTRLRKEKIQTPVLILTAQSKVDQRVKGLDAGADDYLTKP
                     FAIDELLARVRALLRRGTAESSGTLQIDDLILNPATREVTRGGQRIDLTVKEYALLEY
                     FMRHAGRVLTRPMISDHVWNQDFDTFTNVIDVYVNYLRNKIDRGRARKLIHTIRGSGY
                     MLKVD"
     gene            25630..27033
                     /locus_tag="PK063_10145"
     CDS             25630..27033
                     /locus_tag="PK063_10145"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ97454.1"
                     /translation="MPLRVRLTLWYGTALALILLTFSVVLYTITARGLRDQVDESLQE
                     TASAAVRSLETRGFLPLIDEDALLSQFPELTRIDKFFQIFSPTGTITIRSPNIRQHDV
                     PLSRPALEAAFTGSTVFESARYPNEPPLRLVSVPIIYRGSLLYIVQVGTTLEGVEETL
                     RRFLLVLLVMAPIALVVSLVGGWFLAGRALRPVDSITVAAQRIAAGDLTQRLHSERST
                     DEIGRLTDTFNNMIARLETSFAQIRQFSSDASHELRTPLTVMKGESELVLRRPRPVED
                     YIAVLESNLEEIDRMSRIVEELLFLSRADMGQVKTECEPVRLEALVEDIQRQACLLGQ
                     EREVDVIMGTIQPATVRGDELRLRELILNIVDNAVKYSHPCGKVEIDLRVEGSTARLA
                     VRDYGIGIPQDAHKQIFDRFFRTDDARAHTKKGTGLGLAICAWIAEAHHGHIEVQSEV
                     GKGSTFTLVLPLAATAA"
     gene            27152..28630
                     /locus_tag="PK063_10150"
     CDS             27152..28630
                     /locus_tag="PK063_10150"
                     /inference="COORDINATES: protein motif:HMM:TIGR02037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegQ family serine endoprotease"
                     /protein_id="HMZ97455.1"
                     /translation="MKRPTPSVSVLAGIAAVSAGLIWSYTPLSPSHASNPSPVVEERP
                     IAPTGALPAAGFADVAKTVTPAVVNITTSGAEEVSDHGRPRGKMDDFFGSPFGPRRFG
                     PPTEPREHRGGGQGSGVIVTQDGYVLTNNHVIAGAKTVTVTLPDKREFKGRIVGSDPK
                     TDIAVVKIDGTQLPTVPWGDSSRLQVGEYVLAVGNPFGLNSTVTLGIVSALGRGHMGI
                     TQYEDFIQTDAAINPGNSGGALVNTKGELIGINTAIFSQTGGYQGVGFAVSTGMSKPI
                     YESLVKTGKVVRGYLGIGIQDLNHDLAKSFGVKGTNGAVVTDVKEEGPADKAGIKQGD
                     VILSFQGTPIEDAVTLQRAVTRTAVGSKATVTVLRDGQEKELAVTLAELPENQQVAKT
                     ETEPSDQPLAGLAVQELDRETAQELGLKGKIQGVVVTTVDPESDAERAGLMPGDVIRE
                     INRKPVTSMKEFDRAASSLKKGQTVLVLINRRGASLYLSAKI"
     gene            complement(28673..30127)
                     /gene="rimO"
                     /locus_tag="PK063_10155"
     CDS             complement(28673..30127)
                     /gene="rimO"
                     /locus_tag="PK063_10155"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: protein motif:HMM:TIGR00089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008172 - S-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0018339 -
                     peptidyl-L-beta-methylthioaspartic acid biosynthetic
                     process from peptidyl-aspartic acid [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HMZ97456.1"
                     /translation="MASSLITPSRAKGKKPTIGFVNLGCSKNQVDSEVMLGTLVAGGF
                     QLTGDARAAEVVIINTCGFIEEAKQESINSIIEHGRLKKSGSCRVLIAAGCLAQRYQG
                     ELLKELPELDGVVGTGEFGRIADICRSLLAPKKRQQRLWLGQPPYLYDADTPRVRLGT
                     PHSAYLKIAEGCNRNCAFCAIPIMRGKQRSRPIDSIVAEARRLAKEGVKELNLISQDT
                     INYGVDLGLKQGLTALLRELVTVDDVRWIRPFYLYPQQVTDELLELYAGEARITKYLD
                     MPLQHISDGMLKRMHRLGDRKHLTKLVERIRTKIPGVFFRTAFIVGFPGETDKQFEEL
                     KQFVLDMEFDRVAVFLYSDEEGTSAVDLDRKVDQAVMEERRNELLALQESISESKNRE
                     YLGRTIEVLVDGVSEESDRLLEARHQGLAPEIDGVVYCERGIARPGEFISVTVTDVAG
                     YDLIAQPAGQTHQPNRSSDSPGLLMPKKAGAGYR"
     gene            30212..30751
                     /locus_tag="PK063_10160"
     CDS             30212..30751
                     /locus_tag="PK063_10160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HMZ97457.1"
                     /translation="MIRTFQGIKPTIPQSCFIEETAVIIGDVVMGEECSAWFHAVIRG
                     DVNSIRIGNRTNVQDLCMLHVTHDTHPLIIGDDVTIGHHVVLHGCTVQNRVLVGMGAI
                     IMDGAVIGEDSVVGAGALVTEGTIVPPKSLILGSPAKVKRPVTEQELAWIRESAQNYI
                     RYSRQYLTGPDKPRPGFWV"
     gene            complement(30782..31480)
                     /locus_tag="PK063_10165"
     CDS             complement(30782..31480)
                     /locus_tag="PK063_10165"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97458.1"
                     /translation="MARKRMSVGPATRRAIKDIFSRLDYAQLGPIYCDEGGDEFWAAK
                     RGPCQRLGTKVATALKARLKPGGTSVYVGAGVAEIPPLVMEALELDRQVVACNLRRQE
                     VLLLNRACGELPIRFQHVDAGSVKQRVDHLWLVSVLNDPERFPELSVLSYGRANPVTF
                     NAKKFVTQQRTVARLVDRCLSRLTVPGLVTTTVEEAVWVAEWCHRRGIPYRIDERTYA
                     SPTVGDPICLMRIG"
     gene            complement(31709..32605)
                     /gene="argB"
                     /locus_tag="PK063_10170"
     CDS             complement(31709..32605)
                     /gene="argB"
                     /locus_tag="PK063_10170"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003991 - acetylglutamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HMZ97459.1"
                     /translation="MNKLIKKADVLIEALPYIRTFKGKTVVIKYGGHAMTDASLKARF
                     AQNVVLLKYVGLNPVVVHGGGPQIDQMLDRLGMEAKFKHGVRVTDAATMEIVEMVLAG
                     RINMEIVDLLNRHGGQAVGLSGKDGGLMLTKPLTAKAWAESIEKDIDVEDRDADFGFV
                     GDVKSIDPTLLLKLQEDHYIPVIAPIGTDREGNTYNINADLVAGAIAAALKAEKLVML
                     TDVKGIRDANGRHLSTVSRKDVQRMVKRGTISEGMLPKVHACLDALAGGVGKAHIVDG
                     RVPHAILLEIFTHKGIGTEIVS"
     gene            complement(32635..34038)
                     /gene="hslU"
                     /locus_tag="PK063_10175"
     CDS             complement(32635..34038)
                     /gene="hslU"
                     /locus_tag="PK063_10175"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HMZ97460.1"
                     /translation="MTTDSTSRSLNVNNLTPRQIVEALDRYVIGQQDAKRMVAIALRN
                     RWRRQQLAPELRDEVMPKNIIMIGPTGVGKTEIARRLAKLAEAPFIKVEASKFTEVGY
                     VGRDVESIIRDLTEQAISLVKTKHLEDVQEKASRLGEERLLDLLLPGGPSRPASAGFD
                     HAGSRAEAAEPTESPDATRSKLRLQLRDGKLDQRSVEVEVKERALPLGVISNQGGMED
                     LEGNLRDMLGGMFQGKKKKRVMKVPDALKHLTQEEAQKLIDMDEVVREAITKVEQTGI
                     VFLDEIDKIAGRERAMGPDVSREGVQRDLLPIVEGSTVSTKHGAVQTDHILFIAAGAF
                     HVAKPSDLIPELQGRFPIRVELAPLTKEDFVRILTEPRGALVRQYHALMATEGLTVEF
                     TDDGLAEIAATAVQVNERTENIGARRLFTIMERLLEQVSFEGSELEQKAVVVNAAYVR
                     ERLLNIVKDQDLSRYIL"
BASE COUNT         7098 a        10632 c         9444 g         6928 t
ORIGIN      
        1 ttggagcggg aaacgggatt tgaacccgcg accctcgcct tggcaaggcg atgctctacc
       61 actgagctat tcccgcgtcc gtcggaagaa gcgggattct accggccaga tataaagact
      121 gtcaagccag acatcgcaat atccttcgca caacgatcga tcatcttctc gtacgaattg
      181 ttgattctct cgaaaccgtt cgccgcacag agtgcccatc tgccaccgcc atcttggtct
      241 ttcgactcag acctgcctgc ttcttctgtc cacttgacgg acttgagagg cttgagtaca
      301 gtgaatgtaa tgtcgctttt cgctattcct atcaatgagg taaccgtagc gtgacctccc
      361 gcccgcagca gtcggcaccc tttgcagcgc aagccgtttc attcgacgag tatctcgcat
      421 caggcaagat tccagacgga ttgcttgtca gcgagtatgt ggaacagcag ttcgtcgaac
      481 gtctggtcca ctacgtactc agcgttccgg ccggcagtta cagcatggcc cagctgagcc
      541 gcctcctcga gcaattggat cctcgcgccc aggtattttt cttcaagcga ctcaaagaga
      601 acagtccgga cagcctcaaa gattttgccc cgctgtacta cgggttcatg aacgagtttc
      661 actccctcct gttcacctag tcgcggttca tcaaaaaaat tccttgtcgc ccccctaatc
      721 tcaggtataa tcacgagaac ctcttaatga gccaaggagc actatgaatc ccacgttaca
      781 acgcgcagtt acgagtttct ataatctggt gtacgaagcc cagacctttg cgacgaccat
      841 gtcccgcatc gacaccgctg agcaggaaca ttatgccggg cggatcgaag gcctcaattg
      901 ggtcctggat cgctgccagg aactcgagga catggacgcc aacatcacgc cgacgacgtt
      961 gcaacgcgta ctgacggaag tgaaatccga cttggaccat gagctctccg tgcaacgtcg
     1021 ggaaaagggt cgacgggcag acggacgcga ggaggccctg accttcgttg cggactattt
     1081 gtccagcctg atcacggcaa ctgagatcga gtccgcaaaa acctccgtgt aaccgcctgt
     1141 cgattgtctc caggcttatc cttcgttatg gcctcctccg agggcgacta tggcccgtga
     1201 gtggatcatc ttcgccattt gtctcggctt gggaggccat attgccctcg ccgtcgttct
     1261 gcatgcaccg gacatgtggc cgtggagtaa agcctggctg tacggattac tttccggcct
     1321 gactctctat atcgtggtgc aggtcctgcg gtcgctgtgg tgggtttttc gcggacgaaa
     1381 cggcgatgag cccgatgttc cagaagacca gcatattcgc tgacccttgc tcgacgacca
     1441 tcccatataa gccattgcgc gctctatcca gctctcagta gaataccctc catgcagcca
     1501 cgttcgaaca gaccgtcacc acctggttgg cctccgcgtg ccacacagcc ccggaggacc
     1561 cccgcgtctc ctcaaggcca ccgtcaaacg gatcaatacg attcatttaa cgcctccttg
     1621 ctctactgcg gtcattgccg tcaagcgact cccacccgcc agcgcctgct tctcgtgtta
     1681 cccactggaa atctgtacga gtatctctgc gcgcaatgcg gaacctctac aggctccaaa
     1741 acagagagcg cctcaggcga gagcggtctc gtagccccgt agtctccacc agcctgtcct
     1801 cgtctttcgc gatgtagagg aactcccgaa caagggcgcg aagggataca gacagggtgc
     1861 attgccccct gagggcaccc atccaacatc aacatgcttg tgaggtaacc tgagaagatt
     1921 cgaggtggga aaactacgcc acctggtcga gcggaattcc ctcatcgatc aacatgaccg
     1981 ggatatcctc acgcacaggg tagagaatct tattatcgga tcgcactaac ccgccatcga
     2041 gcttttccgt gacagccttt tgcgccttgt tctttaatac tccccgctcg atcgctccgt
     2101 tcaccttttg aatcaacaga tcgtcagcca atacgactgc ctgcttggtt tcagggcaac
     2161 acagaatggc caacaagtct ttgtcgagat tgactttctt ttgcacggca tcgctcacga
     2221 tgaatctcac aatctcaccc gacagggtga ctcaaaggtt acccgaaaca tagtccaaaa
     2281 aaatcggcag atcaagtaga taccaaaact catccccatc tggtatcgta gatgatcgtt
     2341 acccctctcg cgcaccaaca ccaggactca gcgtgacatc ttctcatcga cttggacgca
     2401 tcttttttac cggactgctc ctgctcgttc cggcctggac gacctttctg atcctggcgg
     2461 ccctgtttga aacgctcgac tcgttcctgc tcaacctgat cggtcatcag atccagccct
     2521 acgcgccagg gttggggatt ctgctgctca tcggcatggt gctgatggtt ggagccattg
     2581 ctacacaggt catcgggcaa cgcttcgtcc gttgggccga aacgacgctc gaaggcattc
     2641 cattgatccg cagcatctat ttgactttga agagcatgac ggatcttctg aactaccgcg
     2701 cgcgcttcgg acaaagtacg gtggtcgcgt tcccgttccc gcgcgatggg ctctgggcgc
     2761 tcggtttcgt catgggccca cccccagccg cactacaagt cgctccatcg gtcgaattgg
     2821 tcatggtatt cgtcccgact gccattcacc cgttcaccgg ctatctcgcc atgattccca
     2881 aaacccaatt gcagccactg aacctcttgc cggaagaagc gctcaagttg gaattctcag
     2941 cgggcttgta tcgccccctc cagggctggc tcacagcccc ggcggtgaag tcgtcatgat
     3001 ctccgctgat cagttacgca tccgactggc gaccgtgcag gatgtggacg tccttacgac
     3061 attcagcgca gccatggctt gggagaccga acaccgacga ctcgacctcg cgcgtctcag
     3121 acttggcaca caagccgtca tcgaccgacc tgaacaggga caatattacg tcgcggactt
     3181 gcaccgaaac gctccggccg atacagtgac cgtagggcaa ctgctcctca cgtatgaatg
     3241 gagcgattgg cggaatgccc agttctggtg gatccagagc gtctacgttg accccgcatg
     3301 gcgacgccaa ggcgtgtacc gtgcgatgca tcaagcagtg atggccctgg cgcaatcgcg
     3361 agcggatgtg tgcggcgtcc gtctgtacgt agagggcgac aacaccgtcg cccagggagt
     3421 gtatgaacgg gtcggactta ccccgtcgac ctaccggatt tatgaatccg atttcgtcct
     3481 tcccaaacct tcttcccccg accgccggta gccggcccgg tgggtgatac gcataaggag
     3541 gatcacatat gcgacgagcg ggcctgttgc tgggcgcgat gttgctaacg ctgaacgcct
     3601 gcgcattcag ccgaggcacc ctgggcgaag agatcaagac ggacaccgtc aactcgatca
     3661 aaaagggcgt cacgacccga gcggatgtcc tggcccaact cggcgcgcca gaccgtctgc
     3721 tgcaactgaa cggacgcgat ctctttcaat actaccgcta cgacgccaag gtcggcagct
     3781 tgctcctcat cttgatcaac ttttcccgcg tgtcagtcaa aagcgacgac ctgtttgtca
     3841 tcatcaatcg cgatggaatc gtggaagatg tgatcgcgtc gaagcgcact gaaaatctgg
     3901 agttcaggtt ctggcccttc ggagactgac gccgtgttac ccaggactgt ctcgcgcaca
     3961 ttccttttcg ccgcgatact gatgatgccc ttgtccggct gcaacgtcgc gcgcctgacc
     4021 atcaatactc cactgactcc ccaaacagtg tctttcatta ccgaggggca gacgacgctg
     4081 accgatgtcg taaacaaatt gggcgcgccc gactccatta ccgatgccga gggtggagca
     4141 gtggtgacct atcggtttct caacgccaag tactcgcggg tgaactttgg ctggctggtc
     4201 aagccctggt cccccgtgga cccggatctc gtcttctctc gctccggcat gggcacggac
     4261 gcattcgagc tcctgtgcga ctctaactgg gtcgtgacac accaggcatt cgtccgtcat
     4321 cgtccggatc cattgtttac accctatccg ttttaacctg cccagacacc atcgccgttc
     4381 acgaattgct gccttgctcc catctcgtta taatgccgct catgggcgca gggtcctccg
     4441 acgagtcagc gagccgacat cctcacagcg cgtcttcttc ctatatcccc gccgatcgcg
     4501 acatcgactt tctccagcgc gatgagttac gcccgctccg tctcgggctg gaactcctga
     4561 agccggaatt gatccaaata gaacaaggca tccgttcgac gatcgtggtc ttcggcagtt
     4621 cccggctagt tgaaccttcc cttgcgcgcc aggcgctaga agccgcgaag gccgagttgc
     4681 agatcgcgcc gcaggatgcg ctgcgacagc agcaggtgac gatggccgaa cgccgcctgg
     4741 ccatggcgca ctactatgac atcgcccgtg aattcggccg cctggtgtcc gcgacgtgcc
     4801 aaatcaacgg gcagtgcgac ttcgtcattg tcaccggcgg cggacccggc atcatggaag
     4861 ccgccaaccg cggggcggca gacgccggcg ccaagtccat aggactcaac atcaccctcc
     4921 cgcatgaaca acaaccgaac ccctacatca caccggattt gtgtttccaa tttcgctact
     4981 tcgcgttacg taaaatgcat tttctccttc gtgcccgagc gctggtcgtt tttcccggcg
     5041 ggttcggcac gctcgacgaa ctcttcgaga ccctgaccct tctccagacc ggcaaaaccc
     5101 gcaacattac gatcgtcctc atcgggcggg cctattggga gcgactcatc aattggtcca
     5161 tgctggcaga tgaagggctc atcggtccca acgatctcgc gctcttccat tttgcagaaa
     5221 cggctcaaca ggcatgggac ctgatcagtc agacccatgg aggccctgcc gcacgatgaa
     5281 gatctcgttc catggcgccg cgcgttcagt caccggaagc cgtcatgttc tggaaatgcc
     5341 aggcagccga atcctgttgg actgcggtct ttttcagggc ccacggcagg aggctgatcg
     5401 gcaaaaccgc ttcttaggat tcgatccgcg ctcgattcaa gccgtgctcc tgtcgcatgc
     5461 gcatatcgac cactccggcg cccttcccgt cctaggccag caccggtttc gcggggatgt
     5521 ccacatgact cgtgccacgg ccgacctgac cgccgtgatg ctggaagact cggcccgcct
     5581 gcaagaaaac gactgcgcct acctgaaccg gaaagaacat cgtcgcggac agaagtgttt
     5641 gaagccgttc tatgagacac gggacgcgcg agccatcatc cgccgtttcg ttggcgcgcg
     5701 ttacggtgac accatcaagg tgacgcctcg cctcaccgct tccttccatg atgtcggaca
     5761 cattctcggg tccgccgcca tccggctcaa atactccgcg cgcggcaaca gtaccaccgt
     5821 gctgttctcc ggcgatttgg gacgatccca catgcccatc cttcgcgacc cgacgccgcc
     5881 gccgagttgt gatgtgctga tcatcgaatc cacctacggc gatcgacttc acgaggaggc
     5941 cggggaaacc ctgaccaaga aagcgcaaca gctcgtcgca cacgcgaaag cgcataacag
     6001 taagatcatc gtccccgcat tcgcactcgg acggacgcaa gacctcgtga tgcgcatcaa
     6061 acatttggtg gccgaaggcc agatcgatcc gcttcccatt tacatcgatt caccgctggc
     6121 gtcgaaggtc acggacgtgt tccgcaagca ccctgagtgt tacgacgaag agacgtatcg
     6181 cacgttcact tcggaaggcg atcccttcgc cgcccggtat atccggtatg tctcatcacc
     6241 ggatgaaagt aagcgactca acagcgtgaa aggtccctgc gtcatcattg cgtcatccgg
     6301 catgtgtgag ggaggacgcg tggtgcatca cctcaaacat gccattcagg acgaagccaa
     6361 tatcatcgct atcgtgggct ttcaggcaga acataccctg ggacgcaggc tggttgaggg
     6421 ctgggatgtc gtaccgctgt tcggcattcc cacggcacgg cgcgcgcagg tcgtcgtgtt
     6481 caacggattg tcggcccatg cggatcggaa cgatctactc gcgtatgtga gagcgatttc
     6541 tcctccgcct caacacatct ttgtggtgca tggagaagaa aaacaggcac tgtcactggc
     6601 ggcggcgatc caggccgaat acccacgaac ttcgattgtc gtgccgcaca aagaaagtag
     6661 ttatgaagtc tagcgtcact ccgcgcttca cagccgatga cgtatggagg atgccgtcaa
     6721 catgagccat tcacaccccg ggtccttttc gatcatcgcc tgcgtggttc tcgtgatgac
     6781 gacaggcgtc cattccggat ggagcgcaga gacgctcagc gacgtgactg aagaaccgcg
     6841 ggtacgcgct cgcgccctcg gcctgacact cggacaattg gagcccggcc cgctgaatgc
     6901 cattactgat gtgccgggag tgaaggtcgg gcaggtgacc ttgaggcgtg gagaaggacc
     6961 gcttcaacca gggcaggggc cagtcagaac cggcgtcacg gtcgtcgtgc cacgagagga
     7021 tgtctggcac aagaaagtcc cagccggggc cttcgtcctg aatggcaccg gagaaatgac
     7081 tggtctggcg tgggtggccg aatcgggatt tctcgaatat cccatcgccc tgaccaatac
     7141 gctcaatgtg ccgcgggttg ccaatggcgt catcagctgg atgctccgcc gctacccggg
     7201 aatcggcatc accgacgaca ccctcacccc ggtcgttgcc gaatgtgatg acggtcgctt
     7261 gaacgacatc cagggccgcc atgtctctga agcggatgtc atgcaagcct tagacgatgc
     7321 ggcatccggg ccggtctccg aaggaaccgt cggagccggt accggcatga tttcgtatgg
     7381 cttcaaaggt ggcatcggca cagcttcccg gcgccttcct gctgccgccg gcgggtttac
     7441 ggtcggcgtg ttggttaacg ccaatcacgg tcgtcgccct gaactcatga tgggtggggt
     7501 gccggtcgga caacggtatg atgccgcccc cacacaatcc ggtgcactgc tggaatccaa
     7561 tccggaacgc ctgcatgcca gccgtgaagg atccagcggt aacgccgaag gatcgatcat
     7621 tatcatcgtc gccaccgatg ccccgctcga cagccggcaa ctgacaagac tcggaaagcg
     7681 agccgcactg ggactggctc gaaccggctc gaccgctcgc catggaagcg gcgatttcat
     7741 gctggccttc tccaccggca atgtcatccc ccattacccg accgagccaa ctttttcact
     7801 cacgcatctg gctgacacgc atttgaatgc cgtgattacc gccacggttg aggccacgga
     7861 agaagcggtc ctcaacgcgc tgacgggcgc caccaccgtg acgggacggg atggattccg
     7921 ggccgaggca atctcgcttc cgcgactccg cacactgctg tcaccggatc cagccatcgg
     7981 gcggtgaacg agacgaacga ggccgggcgg caccttgctt ttacaggtac tcacggctat
     8041 tctcctggct cgtctgtatc ggatgcggag ggctatggct gattattcca tgggaggcgg
     8101 actcacgctt ctcaccgcgc tcgaaaagag cgataagttt gcggacttct taaagacgcg
     8161 aatggcgcaa gccctggaaa cgcgagaccc gaccgagctc cattatttgc tcgcgcagct
     8221 ggatgattat cattcgtaca tgtggcgtta ctacaaaaag ctcgccaccg aacgacctga
     8281 acgcatgaat cctggcgtct gaccccctcg gcggcacgcc gtccatccct attcagcagg
     8341 acatcccgtg attatgactg ccccgtcaac gctacgattt gcctccgctc tgacacgcca
     8401 cgcggacgct caggctgcgg ccgctgactt gattcacgcc atccgcgagc aactggggcc
     8461 gtcgcgcatc gatgtggcct tcctgttcat ttcggctcag catgcggacc aggctgaggc
     8521 actttcggaa gctcttcgca ccgccttggg cccagtcacg ctggttggct gtacgggcga
     8581 gggcatcatc gcgaccgggc gtgagatcga atcaggaccg gcggccactc tctgggccgc
     8641 tcacctgccc ggcgtgctcg tccaaccgct acgactttcc ttttcaagcg tccatgatca
     8701 gttttcgctg cgcaattggc cggatctgga tgaggtgggg gacacggccc ctgtcatgat
     8761 gctatttgcc gatccctttt cgacgcccat gcaagaagtc ctttccgtca ttgaggaaca
     8821 gtaccccggt acccgcaccc tgggcgggct cgccggcggc gggcaggacc tcggcgaaaa
     8881 tcgtctattc ctcgacgatc aggtgttgac cgacggattg gttggcgtgg ccctgtccgg
     8941 caacattgcg gtccgctcgg tcatttcgca aggctgccgt cccatcggtg accgcttcat
     9001 cgtcacgaaa tccgagcaca acgtgattca agagctcggc ggcatgccgg ctttgcattg
     9061 cttgcagacc gtatttgaac agctcagcag cgatgaacgg gcccaggcac aacgggcatt
     9121 gcatatcggc attgcaatgg atgagcaacg cgcgcaattc actctcggcg atttcctgat
     9181 ccgcaatcta ctcggtgccg atcagcagac cggcgcgatc gtcatcggtg atgtcatcca
     9241 ggaaggacag accgtccagt ttcaagtccg ggatgcccat tccgcggatg aagatcttca
     9301 tgccttgctc gccgcacctc ctcagggcgt cccgtccaaa ccgctcggcg cgctgctgtt
     9361 cagttgttgc ggacgcggca agggactctt tggcgttccg catcacgatg catcggtttt
     9421 gggcgagcaa ttaggcgcta ttccgctcgc cggatttttt gcgcagggag aagtgggccc
     9481 cgtgggcggg cggaactttc tccatggcta tacggccagc atcgccattt tctcggaacc
     9541 tgagcgaggg catcagacag ggctcaaccg ctgagtgctc cgagtgtcct atttgtgatt
     9601 caggtcacac aggaactgaa aggtacgtat gacgactcgc ttctggtgga caacttgcgg
     9661 tatcgtgggg ctcgtattca tgaccatagg gaggccaatg atggcgaaca gtgaacaacc
     9721 cgggacgacg gcagaagtca cgaccgcatc cgggctcaaa tacgtagacg tcgttgtggg
     9781 caccgggcgc gaagccgccg caggcaatct ggccacggtg cactataccg gctggctgac
     9841 aaacggcaag aagttcgaca gctccgtcga ccgccgcgat ccgttttcct tcccgatcgg
     9901 agcagggcag gtcattcgcg gatgggatga aggcgtggcc ggcatgaagg tcggcggcaa
     9961 gcggaagctg acaattccac cggaactcgg gtatggagcg cgcggcgccg gcggagtgat
    10021 tcctcccaat gccacgctag tgtttgacgt agaattgctc gaagtccgat aaggcccgat
    10081 gatggtccgg cctctgcgta tcttcaccct ggatttcacg cacatccgat gaaacagacg
    10141 ccactcatag acgcgcatcg caacgcacaa ggcaagctgg tcgattttgc cggatgggag
    10201 atgcccattc aatattccgg cgtggtcgat gagtaccaga cggtccgccg ccatgcggga
    10261 ctgttcgatg tcagtcacat ggggcgtatc cgtgtcgcag ggcccggctc attggccttt
    10321 ttgcaacgcg tcacgacgaa cgatgtctcc aaactgtcgg tccgccagtc gcaatactcg
    10381 atggtctgtg cgccgaacgg cgggattaag gacgacatct tcatctatca cgtcaaaccg
    10441 tatgaatttc tggtctgcgt gaatgcgtcc aatcgtgaaa agatcgttgc ctggtttcac
    10501 gaaaaggttg cgcaagccca gggatgcacc gtccaggacc agtcaaccac ccttgcccaa
    10561 attgcgattc agggccccgc ttcccgcgac attctcaccg ccgtcggcct gactgatctt
    10621 ccgctcctga aaatccggca ctgcctggac gccgtcgtct gtggccatgc aaccctggtg
    10681 acacgaaccg gctataccgg cgaattgggc tatgaattgt accttccggc cgaaggcgcg
    10741 atgaagatct ggaatcgtct ccttgaagcg gggcacccgc ttggcatgaa gccggcgggt
    10801 cttggcgcgc gcgatttatt gcgactcgaa atggcctacc tgctgtacgg caatgacatg
    10861 gatgagggca cttcacccat tgaggccggg gcggactggg tcgtgaagtt cgataaggga
    10921 gaatttatcg ggcggacgcc cttgctggca cagcacaacg acgggccatc gcggcgcctc
    10981 gtcgcctttg agctcgtcga aaaagcggtg ccacggcatg ggttcaagat tttgagcacg
    11041 caggatcaac atgccgtgat cggcgaagtc accagcggaa atctgtcgcc cctcctacaa
    11101 aaaggcatcg gcatgggata tgtcactccg gctgcgtccc aaccggggtc gtccatcctg
    11161 atcgatatca gaggaaaatc ctgccctgcc gtcgtcgtca aaccaccgtt ctacaagaag
    11221 cagcccagca cgccatagtc cgcgcacgtc atggtcagac cgatctacaa aggcaccgtc
    11281 gtcacactca acgtggatac ggtgcgcttg ccgaacgggc acacgatcga tctcgaagtc
    11341 atccgccatc ccggcgcgtc ggctgtcgtc ccgctgaaga aagatggaac ggtggtactg
    11401 atccgccaat tccgccatgc ggccaacggg tttatctacg aaatcccggc gggcaagctg
    11461 cacccgaacg aagacccctt agactgtgcc gctcgcgaac ttgaggagga gatcgggtac
    11521 aaggcgggtc gcttccagct gttgtccagc atttttacag ctccgggctt tgccgatgaa
    11581 gtcatccacg tctatctcgc aacagagctg accttgggca cccagaatct ggaccaggac
    11641 gaagttctgg acgtggtaga gatgcccctg aaagaggcta tcgacagaat agaagacggg
    11701 acgatacggg acgcaaaaac gattgtcgga ttacaagcgg tctatattcg gcaggtgggg
    11761 aaccggtaaa cgaccgaaga ggcctcccac catcaggatg ggagacctct tcagacagct
    11821 agcctcgcca aaaaacgggt gactcttagt ggccgccctt cttctcgtct ttcttcttct
    11881 cttcgccgaa cacggtctgg gacaagtgtc cacccttctt ctcttccttc ttcttgtcgt
    11941 caccgaagag ggtctgggag aagtggccgc ccttcttctc ttccttcttc ttgtcgtcgc
    12001 cagcgaacga aggcgcgctg aacgccacca acaacgctgc cgccatgacc gtcaacatca
    12061 tcttcttcat actgactacc tcctgttagg tgtgaagtaa ccgaccgccg acgggtgttc
    12121 gttatagcaa ggtccttgcc gtatggatgg cgggcgtaac ttattgtttt tctgcacatc
    12181 gactgttgaa atggttcaaa tacctcataa cgccggggtc cattctgtgg cagaatagcc
    12241 ttgccgatac taaaccgcct cattaagcga ctctcaaatc cgatacacca ggccaggcgc
    12301 attcaaccaa tagatgcttc cagacacatc atgcacgggg ataccgttgc cactttcctt
    12361 gccggaccat ctcgcaccga atctcaacat cctattcgta ggcatcaatc ccgggcttcg
    12421 ctcggccgca gtcggccatc actatgcggg ccattcaaac cgcttttgga aactgctcta
    12481 tgatgcggcc ctggtgccgg aacccctcac ctaccatgac gacgaacggc ttctggaatg
    12541 gggcctggga ctcaccaacc ttgtcgcgcg cccgactgcc ggatcggaac atctcaccgc
    12601 cgaagactat gcgacaggcc ggcgagccct gatggaaaaa cttcgtcgat atcgcccgcg
    12661 tgtgaccgcg ctggtcggca tcacgctcta tcccatcctc tttcccttgg aacccaaaca
    12721 agcagggcgc aaacccggac tgcaatcggt gacgctgtac gattccagta tcgtgttgct
    12781 gcccaatccg agtggacgca acgcggcata cccttatcac gctctcttgg acgcgttttg
    12841 cacgcttaca ccgtgggtca ggacttctct aggataagtt ctcccatgac gctacccacc
    12901 acatgctata ctctggcatt cagcgaggtc gttgctgtac cattcgtcct ctttttcact
    12961 ccatctcaca tgatcggtgc ttcatgaact atcccgttat cgcattgtgg ggcttgctcg
    13021 gcgtagctct catcggcgag caagctgttg ccggtaccgc cgtgcaacgc ctcactgccg
    13081 agtccatgca tgaatgttcc ctgggacggc aggcgcagac tcgtgcggac cgcattcaac
    13141 attttgcgtc agggcaagca ttcggcgagc aagccgttgc ggcggatgaa tcatcacctg
    13201 acgcgcattt tgccctgttc tgtaatctcg gcgagcaact tcgggtggac ggagaaagcc
    13261 tctcgtcgct gtttggattc cgccgcatga tgaaggagtt gaaccggacc ctcgaactgg
    13321 acccgagtca tttggatgca ctgtcagcca aaggcaccgt attggtccgc gtgccgggat
    13381 tcatgggagg agataaggaa aaaggagaac tactgctgcg tcaagtgatt gctcgtgaac
    13441 cagcagccgt caatgctcga ttgagtctgg ccaaaagcta ctgcgccgac gggcgacatg
    13501 aagaagccgt cgccattgcg acgaaggccc tggatcttgc ccaagaactg cagcgcgccg
    13561 atttcatacc ggaagctcgc caagtccttg cacaactgcg ggcccaatcc accaaaggca
    13621 attaaccacg cggcggcatt cgcctgactc cggttcggcg aagccggtcg atatcgcccc
    13681 tggccggcat tgctgcctgc gcgccatatc ccgtcgtagc cagggccccc gccgcagcgg
    13741 ccatttccac ggcttcctca atcgacaggc cttcagccaa gccacaggct aacgccccat
    13801 taaaggtatc cccggcaccg gtcgaatcaa tcgcgtcgac gataaaggcc ggaatatgcg
    13861 tcacgtgctt cccgcgtgag acgacggctc cctccgtacc gcgagtgacg acgactgttt
    13921 ccgccccggt gctgaccaac actctggccg cgtcggccgg gtctgtggca ccggagagta
    13981 cgcaggcctc acgttcattg ggcgtgagaa tatccaccat ccgcaaagac tccggtggca
    14041 acggacaggc cggcgctgga ttgagaatcg tacggagtcc ataccgctta gccagccgta
    14101 gacattgctg aaccgtgtcg atgggaattt ccatttgaac gagcaggact cgcgcgtcgg
    14161 cgatcagctg ggcgtgttgc tcgacatccg ccggggtgag ctgctgattg cttcctggca
    14221 ccaccacaat ctgattgtcg cccgcgacgt caacaagaat catcgcgacc ccggtctgca
    14281 ctgcggcatc acgcaacagc atgagtcgtg acaagccctg cgtagccaga tgctgtgcta
    14341 tcaggtcgcc gttgaaatca tttcccactt tgctgaggaa cgcgacgtcg gctccggctc
    14401 gcgctgccgc gacagcctga ttcgccccct tgccgccgaa cgattgcagg aatcgatgcc
    14461 cgaggagggt ttccccgcga gccggtaacc gatcgactac cgcggtgaag tcgatattgc
    14521 tggaaccgac aactacgacc atggacacaa tcgactgcgg atcacactca atgcgcgctc
    14581 ggcatcgacg tccaccgcga cctgcatgtt cgggttcgct ttttcttccg gcctgcgatg
    14641 gcgccggtcc gcaacagtgg ctccgcggga cacacgcccc accacttcca cttcgacatg
    14701 cagcggctcg gttttgagca atgatggttc aatggccgca aggaccgcca tggggtcatg
    14761 gaagtacagc aatccatgcc cttcaacctg ttctgcaaaa tcgaatgcct tggcggtcat
    14821 gtctgccacg atacgacagc gtggatcgcg cgaggcaccg gtccacatct tcaggacatc
    14881 acgacgcagc ccgacacggg tggtcacgtc cagcggcacc agggttaatg gaagcgccgc
    14941 ctgaaacacc cgatgggccg cgtggggatc gacatacata ttgaactcag ccaccggtga
    15001 tacgttgccg ggcacaccga tcgcaccccc catcacaatc acggaacgaa acttctggac
    15061 ggtaagtgga ttgactttca gcgccacagc cacattcgtc agcggcccca gggtaataag
    15121 cgtgatgtcg tcctgatacc gccgcacaca ttcgttccac acatcttggg cagtggacag
    15181 gagaggcggt agacgaacag cggggtaccg catcgttccc tctgcagaca gcagagcatc
    15241 cagttcaccc agcccgtcac tcccatgtac gtgaacggcc gtttcaaggg cttcttccaa
    15301 gggccgcgcg gcgccctgtc ccaccagcaa gccaggcgga gggttgagaa gattcaagag
    15361 gcgaaacaga ttcttcgtgc cctgtcccac tggcacattg ccgcagacag tagtgattcc
    15421 caccacgtcc aactcaggcg aggccaaggc caggagaatg gccagggcgt catcgacgcc
    15481 ggggtcggta tcaataatga ctttggttgg agaagtcttc tgcatgcctg aatgatacga
    15541 cgtcgggaga gaagagggag ggatccacct tcgtcccgac acatgcacgg atcactgcgt
    15601 cttacaagcc ggcgtcacgc ctcggagtgg actggacgaa gcgtgtcgat tggccaagct
    15661 gttccagtac ggactggagg acggacatgt tgtggggcgg ccccatgaga aaataaatca
    15721 ccgccgtatt gtccgctccc atgaccgcca acgcccggcc ggccattcct tctccctcgt
    15781 acgattgcgc gatccatgcg tcggtttctg cttgcgcgcc cgctgggata aaggagagtc
    15841 catgcaacag caacagcggc tcacgaagtt gttcacgaag ggcgtctcgt gtgaccttgg
    15901 ccagcggaaa catcatgccc agttccttgc cttcctctgg aatgagaaac ggcatctctg
    15961 catcgtcagg ccgattgctc tgccaaccat cgggaaccac aaatgaccag ccagtccccg
    16021 gaattctcaa tcgtgtgccc gcacgatagg tgagtccgga taccacgtcg agcggactat
    16081 cctcgatatg agtgtcctca acagcaacgg attcaatggc ggcgtggacg ggcagggcga
    16141 agaacatatt gagcagcaga caaccgatcg cgatctgacg gacgacacgc cgcacacgac
    16201 ccacagcggt caaccacgtg ccgccgccag aagcagaatc acgagacggc atccaccggc
    16261 ggacaggtgc aaaagaggtg gcggtctcca taggcttcat cgatccggcc cacactcggc
    16321 caaaacttgt tctcgcgcac ccatgaagca ggaaatgccg cttcttcacg ggagtagggt
    16381 cttgtccatt ccgaggcagt cacggccatt gccgtgtgag gagcattctt cagcacattc
    16441 cccgcgcgcg gctgccgacc ttccgcaatg gcctgaatct ccccacggat cgcgatcaac
    16501 gcgtcgcaca accgatccag ctcacttttc acttcactct cggtcggctc aatcatcaag
    16561 gtgccagcca cggggaatga cacggtgggt gcatggaatc cgtaatccat gaggcgcttg
    16621 gccacatcca tggcttccac gccgctgctg tccttgaggg gacgtaaatc cagaataaat
    16681 tcatgcgcca cgaatccgcg tgccccgctg tacaagaccg gatagaactt ctccaggcgt
    16741 ttggccatgt agttggcatt gaggatggcc acctgcgtcg ctttggtcag cccctcgcgt
    16801 cccatcaacg caatatagac ccatgaaatc gtcaggatgc tgggactgcc gtaaggagcg
    16861 gctgagaccg gcccgattga ctgcggtccg cccaatttcg tgaccggatg tccgggcatg
    16921 aacggcatta aatggcgggc gacaccaatg ggtcccattc caggaccacc gccgccgtga
    16981 ggaatacaaa acgtcttatg caagttcaga tgacagacat cagcacccag atcggccggc
    17041 cggcagagac cgacttgcgc attcatgttc gcgccgtcca tgtacacctg tccgccatgg
    17101 gtatgcacga tctggcacat acggcgaatg ccttcctcga acacgccgtg agtcgatgga
    17161 taggtcacca tcagcgccgc caagcggcta cgatgctgcg tggccttggc ctccagatcc
    17221 gcgagatcaa cattgccgcg ctgatcacag gcaacgggaa cgacggtcat gccgcacatc
    17281 gatgcgctgg ccggattggt gccatgcgcg gaaaccggaa tcaaacagat atcgcgctgc
    17341 gtctcccctc gctgccggtg ataggcccgg atcaccatca atccggcgta ttcgccctgt
    17401 gacccggcat tcggctgcaa cgaaatcccg gcgaatccgg tgatctccgc cagccacgac
    17461 tcaagctgtt ggaacaaggc caggtatccc tggacctgat cggcgggagc aaacgggtgg
    17521 agccgcccga actccggcca cgtgacgggt aacatttccg ccgtggcatt cagcttcatc
    17581 gtgcaggaac caaggggaat catcgaatgc accagggaga gatcccggga ttgcagacga
    17641 tggatatacc tcaacagctc atgttccgcg tgataccggt gaaacaccgg atgcgtaaga
    17701 tactggctgg tgcgagcaag cccggccgga taccgcccgt cgaccgattc aagaatggtc
    17761 tgcagttctt ccggggaaat ctcctggccg gcgaagagcg tcagcaactg ccgcacttca
    17821 tccaccgtgc tccattcgtc cagcgacagt cccaggctgt gatcatcgta tcggcggaga
    17881 ttaatcttct gctgccgcgc ccggttcaca atcgtctccg attgtgccgg cgagagcggg
    17941 acccggaggg tatcgaagac cggctccagt ccgaccgcgc aaccatgccg gcgcagccct
    18001 tcggccaagg ccatcgtgag accgtgaatc cgttccgcaa tgcgccgtag tccggcaggc
    18061 ccgtgataga ccgcatacat cccagccata actgccaata acacttgcgc cgtgcagata
    18121 ttgctcgtcg ccttctcccg acggatatgc tgttctctgg tttgcaaaga taaccggtag
    18181 gccgggcgcc cggtgacatc tttcgacaca ccgatgatcc gacccggcat ctgccgtcga
    18241 aactcttctt tggtggccat gaaggccgca tgcggcccac cgaatcccaa gggcacaccg
    18301 aaccgctgac tggaccccac cgcgacatcc gcgccgaact ctcccggagg acgcagcagc
    18361 gtcaaggcca gcagatcagt cgcgacgacc acatagactc cggcggcatg ggcgcgcgta
    18421 atgaattcgc tgtaatcgcc cacgtacccg tccgtcgagg gatattggag caacatcccg
    18481 aagaattcgc ctgaggacaa atccaacgat tgaatcgcac cgacctgcag gacgatgccc
    18541 aagggttccg cgcgggtctg caccaccgca atcgtttgcg gatgacaggt ctcagacaca
    18601 aaaaatttgt gccggtcgtg accggccgcg cgggaaatcg cggcgcacat cgtcatggct
    18661 tcggctgccg cagtcgcctc atccagcaaa gaggcgtttg caaggggcaa gccggtcaaa
    18721 tccgccacca tggtctggaa attgaccagc gcctcgaggc gaccttgggc gatctcggcc
    18781 tgatagggcg tgtattgcgt gtaccacccc gggccttcga ggatattgcg ctgaatgacc
    18841 ggcggcgtga tgcaatcgta gtagcccatc ccgatcaagg accgccagac ctgattctgc
    18901 ccggccattc cgcgtaattc cgccaagacc tcctgctcgc cgcgcgggga tggaaccgcc
    18961 agggagccct gcaaccggat atcggaagga accgtggcct caacgagaga gtccagcgag
    19021 ggcacgttta ctgtttccaa catcgtctgg atttcagact cagtcggacc gatatggcgg
    19081 ggcacaaacg tatcgttcgg ctcgagaaac tgcggttcag gcatgggggt gaagtcctgc
    19141 tataaggtga cgcactcgtt cattcgaggc agagtgggta ccctatcatg cagcaccgag
    19201 ttttccaagc gttcagcggc catctcacct cgcttgtttt cccaatttcc atagcgtaat
    19261 agtgagatcg accttgcgcc acaggcaacg ttgaccgtca tcagacgcga ccaagacaag
    19321 aagacttcat catgacccat gacattctcg tggttggagc aggactcgcc ggcatgcggg
    19381 ccgctattgc cgtgccgccg gacctcaatg tcgcgctgct ctccaaggtg catccgatcc
    19441 gcagccactc cgtcgccgcc caggggggaa tcaacgcggc catcggcgca gaggactcct
    19501 gggaggccca tgcctatgac accgccaagg gagggctgta tctgggcgac caggacgcca
    19561 ttgaggccat gtgcaaagaa gcgccgcagg acattctgga attggagcgc atgggcgtca
    19621 tcttcagccg caccgcggaa gggcgtattg cgcagcggcc gttcggagga gccggctatc
    19681 cccggacctg ttacgcagcg gaccgcacgg gccatgccct cttacacgcc atgtacgaac
    19741 agctgatgaa gcgccgctgc aaagtgtatg aggaatggta tgtcacggcc ttgctggtcg
    19801 aagagggccg ctgttgcggc gtcgttgcct gggacatgat ccatggtggg ttacagatgc
    19861 tccgcgcgaa agccgtgatc ctggctacgg gcgggagtgg ccgcattttt tccacgagta
    19921 cgaacgccgt catcaatacc ggagatggca tggcgctggc gtatcgcgta ggaattgcgc
    19981 tcgaggacat ggaattcgtc cagtttcatc cgaccacctt aaaagacacc ggcatcctga
    20041 tcaccgaagg cgcgcgcggg gaaggcggat atctcctgaa cacgttgggc gagcggttca
    20101 tgaaacggta cgcgccggaa caaatggagt tggccacccg ctccaccgtg tccctcgcca
    20161 tcggacagga aatccaggaa gggcgaggtg tcgacggctg cgtcctgctc gacctgcgac
    20221 atctgggccg cgccaaaatt ctggagcggc tcccgcagat ccgggaactg gcgatggaat
    20281 tcgcaggtct cgatccgatc gaaacaccca ttcccatacg tcccggggcc cactaccaga
    20341 tgggcggcgt ccggaccaat gcgtggggag aaaccgagct gccaggactc ttcgccgcgg
    20401 gcgaatgcgc ctgcgtcagt gtgcatggtg ccaaccgcct cggaggcaat tccttactgg
    20461 aaaccattgt ctttggacgc cggacaggca caaaggccgc tgagtccatc cgcaccgttc
    20521 agctgtcacc ggtctccgaa accatcctga agagcgagca acagcgcatc gataagctgc
    20581 tcagcaaccc cggacctgag cgggcctggc agatacggga cgacctcggc aaaaccatga
    20641 gcctgaatct gggaatcttc cgcacgaaac aatccattca agaggctctc agtgccgttc
    20701 aagcgttgaa acgtcgcgcg gaagacatgt gcgtacagga caagggacgc gtcttcaaca
    20761 ccgacctgat tcacgccctg gaattgcagt gtctgctgga gatcgctgag accatcgttg
    20821 tgggcgcttt aggacgggaa gaaagccgcg gggctcacta tcgaggcgat ttcccaaccc
    20881 gcaacgacac ggcctggctt cgccactcat taagctaccg ccgacccgag ggtccccatc
    20941 tggcctatgc gcctgtgacc attacgcgtt tcccgccagc ctaagtcgtc aatcctggga
    21001 cccgacccct gcattccgtt cagcatcgga caacagcctg cccccagcca tcccggcggt
    21061 tgcgctcctc ccgttttgcg ctatcctttt cagtaatcac cgatcactcc actgacggga
    21121 ccgtccatca cgcgcccggg cgaagggtcg taaggcacca tgactaccgt tcaccctggc
    21181 acggcactcc ctgcatcccc tacgctgacc gcgtccgatg cggcacagac tgccatctgt
    21241 cccttctgtc aggcaatcac ctcctgcgca ccagtcgccg gtcatcgttt gcaccagttt
    21301 ccctgccctt cctgccatgc caaccttctg gtcctcaacc cggcggcacg gccgaccgat
    21361 gaagacaaga agactcgatc gtcggacggc gatcttccaa tcgatctttc acaccggctc
    21421 acaggcatcg cagtggctgt cctggcctgt gcgttgaact acgtgttgtt gatgggcatg
    21481 gcctactgga tcctggggca agtaaaaacg acccacgatc cctacgacat cgatgcgttg
    21541 atgttgtcgc cacttatttt gaaagccaat ggctggacgc ccctccacct tgcggcggcg
    21601 cgaggcgatc agtctgcggt cgcaacgctc ctcacagaag gacaaacggt ggaccaacgc
    21661 aacggcaatg ggcggacggc attgtttgaa gccgccaagc gcgggcagac cgatgtggtc
    21721 acgctcctgc tgcaacatgg agcgaatccc agcgcgaagg gcaaacaggg ctttactccg
    21781 ctgttggctg cggcagagca gggccatgcc gacaccattg aggtgctcct taccaatgga
    21841 gccgacatcc gagccacctg cacctgtggt gattcggcgc tccatcgggc ggtccgacat
    21901 gggcatctcg ccgccgcgca gacgctcctc gaagggggca ttccggtgaa ccagaagagt
    21961 cacggcgaga cccccttgga aatcgcacaa cacgacgaag atcacgaact gatcgcgctg
    22021 ctgcgcgcat acggcggtag agagttttct gacgccaagg ccaaacgcgc ggaaggaatc
    22081 gcattccaaa aacacggaca gatcgaccac gcgctcttcg cctatgctga agcattgaac
    22141 ctggatccgg atgatcatga agcctattac ggacgcggaa ccgccctgct ccaaaaaaac
    22201 gcgcctgacg aagcgctcat cgcccttcac gccgccattc gtctgaatcc tacctacctc
    22261 gatgcctaca gcgcagccgc gtccgtgcat acttcacgcg ggcaatggga tcaagccctc
    22321 aggctgtggg atcagctcct ctcacaccag ccccaaaatg gacgtgccat tttcgaacga
    22381 tccatcgtga aacgaggaaa aggcgatagc gcgggattcc tgcaaggatt gcaacaggcc
    22441 tgcgccttgg gccatcgggc cgcctgttga atcatgagca ttgcggcact gcatgacgac
    22501 tcgagcaccg cacgcataac ctgtcaccgc tgcctcagcc attaccgagt ccgcgccctg
    22561 gaacacttga cgggggcctc tcgcagcacc tgccccacgt gcggcgcccg gttcgcggtg
    22621 gtcgacccgg tatcgtcagc ctctgccgaa gtcctgccga cccggcaaga caggccttcc
    22681 gcggttcatg actccgcgtt accaaccgac gcggctgtat ccatgcctgc ccctatgcgc
    22741 gcgtcctttc acggaatggg cgggaccctc ctgggcatgc atgtggtgaa cgtctgcctc
    22801 acgctggtga cgctgggcgg ctatcatttc tgggccaagg cgaagatccg tcggtacctg
    22861 ttcagccaca cagcctttgc aggggatcgt ttcgcgtatc acggcaccgg caaggaactc
    22921 tatcaggggt tcctgaaggc catgctggtt ttcggtattc cctatttttc tctaagcgcc
    22981 gcgcatacct tcctggagct tccgcagtgg atcgatgtct tgctacaggt gatggccggc
    23041 ctggtgttct tcctctatgt ccccgtcgcg atcgtgaatg cccgccgcta tcgatgcacc
    23101 cgcacctcat ggcgcggcat ccggttctcg tttcgaggac ggaccagcga ttttctcaaa
    23161 ctgtattttc ggggatggtt ctttacgatc ctcaccctgg gcacctacta tccctatttc
    23221 caaacgcagc gtcaggcgtt tctgcactcc cacacctatt tcggtaacca gcgtttccgg
    23281 ttcaccggcc atggatcagg agtgatggtc cccttcgcca tcaccctatt taccacctat
    23341 gccgtcctgg ccctgtgcgg gttcgccctc gccgcgcaat tgacgaacgc ggggctgacg
    23401 ctgttgttga tcccctgtgt gctcgggccg atgtggatct ggctgctggg acagaagcag
    23461 cgatacttct ggaatcacac ctcattcgga gacgcccagt tctcatccga gattacctgg
    23521 caacggctgt tcacgctgta tctgggcaac ctcggcctcc tcctggccac cttgggatgg
    23581 gcctggccct gggtcacggt gcggaatgcc cgatttttta tgggtacgct gtcgctccaa
    23641 ggccccgtcg atctcgatcg cgtattgcaa gacacctccg aagcctcggt caccggcgaa
    23701 gggttatcaa acctcctcga caccggcttc gacatggatg cgtgatcatg tccaccgccc
    23761 gaaccgccca ctacctcgac ggccgcacgg ccacacgaca ccgtgtcacc ctcaccataa
    23821 gcccggccgc gctgcagatc gccatgcccg acggcagcac gaaggaatgg ccgtacggcc
    23881 agattcgcca aacacaaggg acgtaccggg gcgagccggt ccgcttggag ttcgggactg
    23941 aaccggcaga ggcggtggtg gtcgccagcc gggcgctctt gaccgatatc cacacggcag
    24001 cgccagcact cgcacaacat tttcacgatc cctcctggcg acagagacgc cttgcctgga
    24061 cgctgggcgc gggactcggg gtgatagtca tgctcatcgg cctgtaccga tggggcattc
    24121 ctggtatcgc ctcagcagcc acgccctacg taccgatcat gtgggaagaa tcacttggcc
    24181 ggcagattgt cgaacacctc gcgccggcaa cgcagcaatg tcgagagcct gagcgacttc
    24241 ggaagatcga tcaggtcgtg caaatgttgg ccgccacaca tccggactct ccgtatcgga
    24301 tcacgctctc cgtggtagac aatcccgcca tcaatgcctt tgctgctccc ggcggccacg
    24361 tggtggttct gcgcggcctg ctggagcaga ccgggagcgc cgagcagctg gccggagtcc
    24421 tggcgcacga actccagcat gtctatctcc gtcacagcac cagagccatc cttgaacaga
    24481 cagccggcac gctgctgctg accgccgtat cgggagatct gtcaggggga ctggcctggg
    24541 ggctgcaagg tgcgcagacg atgggatcat tgcattacag ccgcacccat gaggaagaag
    24601 cggatgtcga aggccttcgt atgatgcagg ccgcccatct cgatccgacc gccatgattg
    24661 ccttttacgg gacgctgcag aagtcggagc aagaccatat cgaaccgccg gattttctct
    24721 cgacccatcc cgatatgagc cggcggctcg ccacgcttct cgcgcttgcc ggcccgcccc
    24781 cgaccgacgc gcgccagttg cttcccggag aagattggaa ggacattcgt accctctgtc
    24841 gcctacaaac cgccacgcgc tccagttcag actcccccga ccttccctga ctggcacgtt
    24901 tgatcgcatc atcggccgtc cgcctctgct ataatccacc cacctgtgga catgacctat
    24961 gcgcgtgctt gtcgttgaag atgaaaccaa ggtaggctcg ttcatcaagc gagcccttga
    25021 ggaagaaagt tacgccgtcg acctctgtga ggacggcgcg cagggcctcg atctggccct
    25081 gaccggcagc tacgacctca tcatgatcga cctgatgctg cctggcctcc ccggtatgga
    25141 agtgctgacc cgccttcgca aagaaaaaat tcagacgccc gtgttgatcc tgaccgcaca
    25201 gtcgaaagtc gaccagcgcg tcaaaggact ggatgccggg gcggatgact acctcaccaa
    25261 acccttcgcc atcgatgaat tgctcgcccg tgtcagggca ctcctgcggc gcggcaccgc
    25321 ggaatcgtcc ggcacactcc agatcgatga tctcatcctc aatccggcga cgcgggaagt
    25381 cacccgcgga ggacaacgta tcgatctcac ggttaaagaa tatgcccttc tggaatactt
    25441 catgcggcac gcaggacggg tgctgacccg ccccatgatt tccgaccatg tctggaatca
    25501 agacttcgac acattcacca atgtgatcga cgtctacgtg aattatctgc ggaataagat
    25561 cgatcgcggg cgggcgcgaa agctgattca tacgatacga gggagtgggt atatgctcaa
    25621 ggtggactga tgccccttcg agtccggctc accctctggt acggaacggc gctggccctg
    25681 atcctgctga cgttctccgt ggtgctctat accatcacgg cccgcgggct ccgcgaccag
    25741 gtcgatgagt ctttgcagga aaccgcctca gccgccgtgc gttcactgga gacccggggg
    25801 ttccttcccc tcatcgatga agatgcgctg ttgagtcaat ttcccgaact cactcgtatc
    25861 gataaatttt ttcagatctt cagccccacc ggcaccatca cgatccgctc tccgaatatc
    25921 cgacagcacg atgtcccctt aagccgaccg gccctggaag cggcctttac cggcagcacc
    25981 gtcttcgaat cggccagata tcccaatgaa ccgccgctgc gcctggtgtc cgttcccatt
    26041 atttaccgtg gctcattgct ctatatcgtg caggtgggaa cgacgctgga aggcgtcgaa
    26101 gaaacgctgc gccgctttct cctcgtgctg ctcgtcatgg cgccgatcgc cttggtcgtt
    26161 tctttggtgg gtggatggtt tctggcggga cgtgccttgc gcccggttga ttccatcacc
    26221 gttgccgcgc aacggattgc ggccggcgac ctgacgcaac ggctgcattc tgaacgttca
    26281 acggatgaaa tcggccgtct caccgatacg ttcaacaata tgatcgcccg gctggaaacc
    26341 tccttcgcgc aaatccgcca gttcagcagt gatgcctccc acgaactccg cacgccgctc
    26401 acggtcatga aaggtgagag cgaattagtc ctgcgccgtc cccgaccggt cgaagactac
    26461 atcgccgtgc tcgaaagcaa cctggaggaa atcgatcgca tgtcccgcat cgtcgaggaa
    26521 ttgctgttcc tctcgcgggc ggatatgggc caggtgaaaa cggaatgcga gccggtccgg
    26581 ctggaggcgt tagtggagga cattcaacgc caggcctgcc tgcttggtca ggaacgggaa
    26641 gtggatgtca tcatgggtac gattcagccg gcgaccgtgc ggggagacga acttcgtctg
    26701 cgggaactca tcctcaacat cgtcgacaat gcggtcaaat attctcaccc ctgcggcaag
    26761 gtcgaaatcg atttacgggt agaaggctcc accgcgcgcc tggccgtacg cgattacggg
    26821 atcggcattc cgcaggacgc gcacaagcag attttcgacc gcttcttccg cacggatgac
    26881 gcccgggccc ataccaaaaa agggaccggc ctaggcttgg ccatctgcgc ctggattgcc
    26941 gaggcccacc acggacacat cgaagtccaa agcgaggtcg gcaaaggatc cacattcact
    27001 ctcgtcctgc cgttggcggc cacagcagct taacgacttc taattcctcg ttaatagttt
    27061 tctcatccag ggctgttacc ttccaattga ctgtcacacg gaagattcat ctctcgcgtg
    27121 tacacatcac cgtcatctag gaggagccca tatgaaacga cccacaccgt cagtcagtgt
    27181 cttagccggt attgccgctg tgagcgcggg gttaatctgg agctatactc cgctttcacc
    27241 gtctcacgcc tccaatccat cgcccgtcgt agaggaacgc ccgatagcgc cgactggcgc
    27301 cttgcccgct gccggattcg ccgatgtggc caagacggtc acaccagccg tcgtcaacat
    27361 caccaccagc ggcgcggagg aagtctctga ccacggtcga ccacggggga aaatggacga
    27421 cttcttcgga tcaccgttcg gcccgcgtcg attcggcccc cccacggaac cgcgggaaca
    27481 tcgaggtggt ggccaggggt ccggggtgat cgtcactcag gatggatatg tgttgaccaa
    27541 taaccatgtg attgcaggag caaaaaccgt cacggtcacg ctacccgaca aacgcgaatt
    27601 taaggggcgc atcgtcggca gtgatccaaa gacagacatt gccgtggtca agatcgacgg
    27661 cactcagctt ccgactgttc cctggggtga ttccagccgt ctgcaagtcg gtgaatacgt
    27721 actggcggtt ggaaatccct ttggcctgaa ctcgacagtg accctgggca tcgtcagtgc
    27781 gctgggccgt ggacatatgg ggatcacgca gtatgaagat ttcattcaaa ccgatgccgc
    27841 catcaatccc ggaaatagcg gcggggccct cgtgaacacg aagggagaac tgatcggcat
    27901 caatacggcc atcttttccc agaccggcgg atatcaaggc gtcgggtttg ccgtctcgac
    27961 cggaatgagc aagccgattt atgaaagcct ggtcaagacc ggcaaagtcg tgcgcggcta
    28021 cctgggcatc ggcattcaag atctgaacca tgacctcgcc aaatcctttg gcgtgaaggg
    28081 aacgaatggt gcagtcgtca ccgatgtgaa ggaagaaggt ccggcggata aggccggaat
    28141 caagcagggc gatgtgatcc tttccttcca gggtacgccg atcgaggatg ccgtgacatt
    28201 gcaacgcgcc gtgacacgaa ctgcggtcgg cagcaaagcc acggttacag tattgcggga
    28261 cggccaggaa aaagagttgg ccgtgacgct ggccgaactg ccggagaacc agcaggtcgc
    28321 gaagacagag actgaaccct cggatcagcc gctggcgggc ctcgccgtgc aggaactgga
    28381 tcgggaaacc gcccaggaac tcgggttgaa gggaaagatc caaggagtgg tggtcaccac
    28441 ggtcgatccg gagagtgatg cagagcgtgc cggcttgatg cccggtgacg tcatccggga
    28501 aatcaaccgc aaacccgtca cctccatgaa ggagttcgat cgggccgcat cgagtctcaa
    28561 gaagggacaa accgttctgg tcttgatcaa ccggcgcggc gcatccctgt atctgagcgc
    28621 gaagatttaa ctgcgggcag aacgacgggg cggggtcccg gtgagcacgg gcttatcggt
    28681 aacccgcccc ggcttttttg ggcatgagca aaccaggaga atcggaagaa cggtttggct
    28741 ggtgggtctg accagcaggc tgggcaatca gatcataccc ggcgacatct gtcaccgtga
    28801 ccgaaatgaa ttcgcccggc ctggcaatcc cacgctcaca atacaccacc ccgtcgatct
    28861 caggggccaa gccctggtgc ctcgcctcta gcagccggtc cgactcttca gacaccccat
    28921 ccaccaggac ttcgatcgta cggccgagat actcacggtt tttggactct gagatcgatt
    28981 cctgcagggc caggagctca ttgcgccgtt cttccatcac cgcctggtcg acttttcggt
    29041 cgagatccac ggccgatgtg ccttcctcgt cggaataaag aaatacggcg acacgatcga
    29101 actccatgtc gagcacgaac tgcttcagct cttcaaactg cttgtccgtc tcacccggaa
    29161 acccgacgat aaacgccgtt cgaaaaaaca cgccaggaat tttggtccga atacgctcca
    29221 ccaacttggt cagatgcttg cgatcaccca gtcgatgcat gcgcttgagc atcccgtcac
    29281 tgatgtgttg cagcggcata tcgagatact tcgtaatgcg cgcctcgccg gcatagagct
    29341 ccagtaactc atccgtgacc tgctggggat ataaatagaa cggccggatc catcgcacat
    29401 cgtccaccgt gaccaattca cgtagcaacg ccgtgagtcc ctgtttgagc ccgagatcca
    29461 ccccgtaatt gatggtgtcc tgggaaatga ggttgagctc cttgacccct tctttggcca
    29521 gccgtctcgc ttcagccacg atcgagtcaa tcggtcggct ccgttgcttg ccccgcatga
    29581 tgggaatggc acagaaggcg cagttgcggt tacagccttc cgcaattttg agataggcgc
    29641 tgtggggcgt ccccagtcgg actcgcggcg tgtcggcatc atagagatag ggcggctgcc
    29701 ccagccagag acgttgctgg cgttttttcg gagccaacag gctgcggcag atatctgcga
    29761 tgcggccgaa ttcgcccgtt ccaaccacgc cgtccaactc gggcagttcc ttcaaaagct
    29821 cgccctgata acgctgcgcc agacagccgg cggcgatcaa gacccggcag gagccggact
    29881 tcttgagacg gccatgctcg ataatgctat tgatcgactc ctgcttggcc tcttcgataa
    29941 agccgcaggt attgataatc acgacttcgg cggcacgggc atcgccggtc agttggaatc
    30001 ccccggccac cagcgttccg agcatgactt cggagtccac ctggtttttg gaacaaccca
    30061 ggttcacgaa gccgatggtg ggtttcttac ctttcgcccg tgaaggcgta atcaatgatg
    30121 aagccataac gaggcagtct acgagacagc ggaaaagtct gtcaaacgag ctctcttgct
    30181 attcgtgcta cagctatcct agattgagcg gatgattcgg accttccagg gcatcaagcc
    30241 cacgatcccc caatcctgct ttatcgaaga aacggcggtc atcatcggcg acgtcgtgat
    30301 gggcgaagag tgcagcgcct ggttccatgc cgttatccgc ggggatgtga actccattcg
    30361 tatcgggaac cggaccaacg tgcaggacct ctgcatgttg cacgtcacac atgacaccca
    30421 tcccctcatc atcggcgatg atgtcaccat cgggcaccat gtggtgctgc atggctgcac
    30481 cgttcagaac cgggtgctgg tcggaatggg cgccatcatc atggacggcg cggtgatcgg
    30541 ggaagactcc gtcgtcggcg caggagcgct cgtcacagaa ggcaccatcg ttccaccgaa
    30601 gagcctcatt ctgggatcac cggccaaggt caagcgtccg gtgaccgagc aggaactcgc
    30661 atggatacgg gaatcggctc agaattatat tcgatattcc cgtcagtacc tcaccggacc
    30721 ggataaacct cgcccggggt tttgggtcta acgacgccac cacaatcagc cgccacgctc
    30781 cttatccgat ccgcatgagg cagatgggat caccgaccgt gggtgacgca tacgtgcgct
    30841 cgtcaatccg gtagggaatg cctcgtcgat ggcaccactc ggcaacccac accgcctctt
    30901 caacggtggt ggtcactaaa cccggcacag ttaatcggct caggcaacga tcgacaagtc
    30961 gggcaaccgt gcgttgctgc gtgacaaatt ttttcgcatt gaaggtcacg ggattcgccc
    31021 gcccgtagga cagcaccgat aattccggaa agcgttcagg atcattcagc acactgacca
    31081 gccagagatg atccacccgc tgcttgaccg aacccgcatc cacatgctga aaccggatgg
    31141 ggagctcgcc gcaggcacga ttcagaagaa gcacctcctg ccgccgtaag ttacaggcca
    31201 ccacctgccg atccagctcc agcgcttcca tcaccagcgg cggaatctcc gccacgcccg
    31261 cgccgacata cacactcgtg ccgcccggct tgagccgggc cttcaacgcc gtggctactt
    31321 tcgtcccgag acgctgacag ggccctcgct tcgcggccca aaactcgtcg ccgccttcat
    31381 cgcaataaat cgggcctagc tgcgcatagt cgagtcgcga aaatatatct ttgatcgccc
    31441 gcctggtggc agggcctact gacatacgtt tacgcgccat gtttctccgt ccagactcag
    31501 tccttgatga cgtgcttcgc tctgagatgt ttatgacact ggcatacggc tcgtgcgcat
    31561 agacgaggga gacgggttag cataccggcg actgaaccat tcatctcagc gccgacgcag
    31621 tcgttcccta ttggccccaa tacgcccggc cccagaggtc cttcacaccg ctgttggttg
    31681 aggtataccc gcgtggttgg ttcactgcct acgaaacgat ctcagtgccg atgcctttgt
    31741 gagtaaatat ttccagcaga atggcatggg gcacccgccc atcgacgata tgcgcttttc
    31801 ccaccccacc ggccaaggca tccagacagg catgcacctt gggcaacatc ccttcgctga
    31861 tggtgccgcg cttcaccatg cgctgcacgt ctttgcggga gaccgtcgag agatggcggc
    31921 cattggcatc ccggatgccc ttcacatcgg tcaacatcac gagcttttcc gctttcagcg
    31981 cggcggcgat tgccccggcg accaggtctg cattgatgtt gtaggtgttg ccttcccgat
    32041 ccgttccaat gggtgcaatg accggaatgt agtgatcttc ctggagcttc aacagtaagg
    32101 tgggatcgat cgacttcacg tctccgacaa acccgaaatc cgcgtcccgg tcttcgacat
    32161 cgatgtcctt ttcgatgctt tccgcccagg ccttcgccgt caacggcttg gtcaacatca
    32221 agccgccgtc tttgccgctc agtccgaccg cctggccgcc gtgccggttg agcagatcga
    32281 caatttccat gttgatacgg ccggcaagga ccatctcgac gatttccatg gtcgcggcat
    32341 cggtcacacg cacgccgtgc ttgaacttcg cctccatgcc caaccgatcc aacatttgat
    32401 cgatttgcgg gccaccgccg tgcaccacga cagggttcaa gccgacgtac ttcagcaaca
    32461 cgacattctg cgcgaaccgc gctttgagcg aggcatctgt catcgcatgc cccccgtact
    32521 tgatgacgac cgtcttgccc ttgaacgtcc gaatgtaggg caaggcctca atcagcacgt
    32581 cggctttctt aatcagtttg ttcatgcgtc actcctcgct cgcgctagtc ccgcttacaa
    32641 aatataccgg ctcaggtcct gatccttcac aatattcagc agacgctcgc gcacatacgc
    32701 ggcattcaca accaccgcct tctgttccaa ttccgagcct tcgaacgaca cctgttcgag
    32761 cagccgttcc atgatcgtaa acagccgccg ggcgccgata ttttctgtgc gctcgttgac
    32821 ctgcaccgcc gtcgccgcaa tttccgccaa gccatcgtcc gtaaactcga cggtgagccc
    32881 ttccgtggcc atcaacgcgt gatactggcg gactaacgcg ccccgcggtt cggtcaggat
    32941 acggacgaag tcttctttgg tgagcggcgc cagctccaca cggataggaa accggccctg
    33001 cagctcggga atgagatccg atggtttggc tacgtggaac gcccccgcgg cgatgaacag
    33061 aatatggtcg gtctggacgg caccgtgttt cgtgctgacg gtagatcctt ccacaatcgg
    33121 caggaggtcg cgttgtacgc cttcacggga aacatccggg cccatcgcgc gctcacggcc
    33181 ggcgattttg tcgatctcgt ctaaaaagac gatgccggtc tgctctactt tggtaatggc
    33241 ttcccgcacc acctcgtcca tatcgatcag tttctgcgct tcctcctgag tcagatgctt
    33301 cagggcatcg ggaactttca tcacccgctt ctttttcttg ccctggaaca tgccgcccag
    33361 catgtcgcga agattccctt cgaggtcttc catcccgccc tgattcgaga tcacaccgag
    33421 tggtaaggcc cgttccttga cctcgacttc tactgatcgt tgatccaatt tgccgtcgcg
    33481 caattgcagt cgtagcttgg agcgcgtggc atccggagac tcagtcggct ctgcggcctc
    33541 ggctcgcgac ccggcatggt cgaatcctgc cgaggccgga cgggatggcc cgccaggtaa
    33601 cagcaaatcg agcagccgtt cttccccgag ccgtgaagcc ttctcctgca catcctccag
    33661 atgtttcgtc ttcaccagac taatggcttg ctcagtgaga tcccgaatga tggattcgac
    33721 atcccggccc acgtagccga cttcggtgaa ctttgaggct tccaccttga tgaacggggc
    33781 ttcggcaagt ttcgccagcc gcctggcgat ttctgttttg ccgacaccgg tggggccgat
    33841 catgatgatg ttcttcggca tgacttcatc acgcaactcg ggggccagtt gctgacggcg
    33901 ccatcgattg cgtaaggcaa ttgcgaccat ccgtttggca tcctgctggc cgatgacata
    33961 tcgatccagg gcctcgacga tctgccgggg cgtcaggtta ttcacattga gggaacggga
    34021 cgtggagtcg gtggtcatga cagggcagat cctaacgcgt gagcgattcg atcacaatct
    34081 gttggttggt ataaatgtcg at
//
LOCUS       DAOQPD010000037        34067 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_539_length_34067_cov_23.787281, whole genome shotgun sequence.
ACCESSION   DAOQPD010000037 DAOQPD010000000
VERSION     DAOQPD010000037.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 34067)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 34067)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34067
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_539_length_34067_cov_23.787281"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            182..697
                     /locus_tag="PK063_10180"
     CDS             182..697
                     /locus_tag="PK063_10180"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97461.1"
                     /translation="MFTSAARRSPWIGRLLLGFVLILGVSCSGKTIQYKDDHDRILRI
                     DQAVESLRKSYVERDRSALEALLLPSGGLDQVQRDIHSDFDTFRDIQLEFSIERILIE
                     GDNIDVFVHWQGQWKRDPGDVGTRQRGHGRLAWVGTQSILLREAQGDLPFGMGTRASL
                     NEDPARSQPKP"
     gene            700..2376
                     /gene="nadB"
                     /locus_tag="PK063_10185"
     CDS             700..2376
                     /gene="nadB"
                     /locus_tag="PK063_10185"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008734 - L-aspartate oxidase activity
                     [Evidence IEA];
                     GO_process: GO:0019363 - pyridine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HMZ97462.1"
                     /translation="MSARSASPKIETDFLVVGSGVAGLRAAIELSRAGRVLMLTKGHP
                     LESNSMYAQGGVAVALSEEDDVGSHLTDTLKAGHGLCRREAVRVLVEEGPERIQELIA
                     WGAKFDKIGKRFAFTREAAHSRSRILRARGDATGNEMVRALMTYAARQPRIQRLDRRF
                     TVDLAVVDGRCCGAIVLNEMSGERTVLPASAVVLSTGGAGQVYARTTNPGNATGDGMA
                     MALRAGALLMDMEFVQFHPTSLYLPSSPPFLLSEAIRGEGGQLRNIKGELFMHRYHPD
                     GALAPRDVVSRAIWSEMAATRARHVYLDVTHLGAAFVKRRFPTIYATCLRYDIDMTEE
                     WIPVSPSAHYMMGGVWTDVHGATTLPGLYAAGEVACSGVHGANRLASNSLLEGLVFGM
                     RAAQSAVAHAGHFSESVQLPSLEELEQGRPTELDDPEKLRSSLRRLMWGKVGLVRSGD
                     SLISASAQLVRWMRLLGKPFSSRAALEVKNMVQVARCITDAALWRENSVGAHYRSDFP
                     EAKRQGWRNHSQLLLGGGQVNGMPSNERDLVLATEAPVGRKPGKKTSGRS"
     gene            complement(2282..2947)
                     /locus_tag="PK063_10190"
     CDS             complement(2282..2947)
                     /locus_tag="PK063_10190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HMZ97463.1"
                     /translation="MARFKRTTPLLLLYATLLLTHAPVQAEVYQYIDANGTISLTNVP
                     NDPRYKRVMSELPRSRSVISDRELDPVIARHSRAHRLHPALIRAVIKTESDFDPLAVS
                     HAGAVGLMQLMPQTAMRFDVRDSYNPDENIGGGTKYLRQLLDRFNGNLPLALAAYNAG
                     EHAVERYQGLPPIPETRQYVVKVLGYYRTFLMNARTSSSRAYVPQAPRSQGRGLAHST
                     ASR"
     gene            complement(3098..3952)
                     /locus_tag="PK063_10195"
     CDS             complement(3098..3952)
                     /locus_tag="PK063_10195"
                     /inference="COORDINATES: protein motif:HMM:NF013247.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HMZ97464.1"
                     /translation="MPKEQAVVSVFDHGFLYGDGVYETLRSYGSRIFMRDQHLARLRR
                     SAEAIGLTIPIPDAQWPDLLHEAMRRNEVGNDRVDAYLRITISRGEGEIGLDPALCPR
                     PTVVILTKVLHPSPPALSRDGVTLTVANTRRNLPEALSPHIKSTNFLNNILAKRESIA
                     AGTFDSLFLNWREELTECTISNLFFISNGTVHTPSLDCGILDGITRAIVMTLAEEEGL
                     PVQEGHYHLADLRQADECFLTNTSMEVMPVSRVDAWPIGDGRPGPLTRRLQARFAASR
                     TRFLAPAP"
     gene            complement(3979..5463)
                     /locus_tag="PK063_10200"
     CDS             complement(3979..5463)
                     /locus_tag="PK063_10200"
                     /inference="COORDINATES: protein motif:HMM:NF012640.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I family
                     protein"
                     /protein_id="HMZ97465.1"
                     /translation="MTAVSHQAFLNGPPQPLVVVRPLPNADAFELYQRLGITDGPSFL
                     LESGNGTNATARYSFFGNHPYLTLTGRAQDYSMKADGHITTAHGYAFDAFRQAFADST
                     IPQPDGLPPFYGGAVGYLSYDLVRSFESLPTLASDDLGLPDLHMAFFDTVAAVDHHTD
                     QLYLMYCPPLSRFRAEPREKLLREGSDRLAELEARLTSISRPHPAPTGPIQTSFVPSQ
                     SRDAYTARVRRCQDYIAAGDIYQANLSHRFTLNLDASWSAADRDRYAGILYSRLRRVN
                     PSPFAGLVRFPELTLVSSSPERLVRLTASQASTRPIAGTRPRGNGESHDVTMRAELLA
                     SPKERAEHVMLVDLERNDLGKVCQYGSVRVDEFMTIEQYSHVSHLVSEVVGTLRPGTS
                     PFDLVRAVFPGGTITGVPKLRCMEIIDELEPVRRGLYTGALGYFSWSGDLDLNILIRT
                     LVLTKDRGYLQVGAGIVADSDPDREYDETLAKAGAFLHILEADR"
     gene            5636..5854
                     /locus_tag="PK063_10205"
     CDS             5636..5854
                     /locus_tag="PK063_10205"
                     /inference="COORDINATES: protein motif:HMM:NF021073.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HMZ97466.1"
                     /translation="MPPSQDPLYAGLGQAVRIGTELLAALIVGGGLGWVVDTYLLDSN
                     PWGLVAGLGLGAAAGIRNAYRSAQRWQS"
     gene            5885..6634
                     /locus_tag="PK063_10210"
     CDS             5885..6634
                     /locus_tag="PK063_10210"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HMZ97467.1"
                     /translation="MEESPLHAFELHDLIPLVPAGVDISINKAVILMWVVVGLVAFLM
                     ISAAAARKLVPGKLQNMAELIVEFIRGIILDTMGEAGMKYFPLIATLFLFILFANLLG
                     LIPGSYTVTSQIIVTAVFAVGIYGLSLVLGFSLHGMKFLGILVPPGTPGWLLPLMIPI
                     ELISQLARPISLAVRLFANMTAGHVILGVLFGLAISGGLLIGWLPFAFTIAMNGLEVG
                     IAFIQAYIFTVLSCVYLGDAVTLHGHSEHAH"
     gene            6670..6900
                     /gene="atpE"
                     /locus_tag="PK063_10215"
     CDS             6670..6900
                     /gene="atpE"
                     /locus_tag="PK063_10215"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014959857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000276 - mitochondrial
                     proton-transporting ATP synthase complex, coupling factor
                     F(o) [Evidence IEA];
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_component: GO:0045264 - plasma membrane
                     proton-transporting ATP synthase complex, coupling factor
                     F(o) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HMZ97468.1"
                     /translation="MDAAAAALVGMGLAAAGFAGAGVGIGYIFGKMIEAVARQPEAEG
                     RVGKYMWIGFALVEAIALYGLVIAFIIMGLRK"
     gene            6974..7486
                     /gene="atpF"
                     /locus_tag="PK063_10220"
     CDS             6974..7486
                     /gene="atpF"
                     /locus_tag="PK063_10220"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: protein motif:HMM:TIGR01144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000276 - mitochondrial
                     proton-transporting ATP synthase complex, coupling factor
                     F(o) [Evidence IEA];
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_component: GO:0045264 - plasma membrane
                     proton-transporting ATP synthase complex, coupling factor
                     F(o) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HMZ97469.1"
                     /translation="MPQFESHFFSSLIFWEILSFGILFFLLYKYAFPSLLGMLEEREK
                     KIKDSLDQAERHRSEAERKLKEYEAKLATAAKDAEALLAQAKERAARLMEENEQRMTA
                     DAERIKGDATREIETERRKAIQDIRSQTTDLAMMVAEKVVGRALTDGDHRRLADEALD
                     ALAKTYQSRN"
     gene            complement(7483..8313)
                     /gene="larE"
                     /locus_tag="PK063_10225"
     CDS             complement(7483..8313)
                     /gene="larE"
                     /locus_tag="PK063_10225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HMZ97470.1"
                     /translation="MVSSTPLIEKISRARHLLREMGSVIVAFSGGIDSTLVLKLAHDE
                     LGMQATGVTAVSPTLPASELALTQQLATEIGARHRVVETDQLEIPQFVRNDATRCYHC
                     KTDLYSLLGKLRSEDATACIVDGTNVDDLGDDRPGLKAAREHGVRSPLLEAGFTKADI
                     REAARELHLSNWDKPAAACLSSRVPRGITITRSTLSRVEQAEAALIQGGFRHCRVRDY
                     GDLARIELAVEELPKLLEAGCREQLVESLKQIGYRFVTLDLEGYRQGGVSLTPPASET
                     "
     gene            complement(8361..9734)
                     /locus_tag="PK063_10230"
     CDS             complement(8361..9734)
                     /locus_tag="PK063_10230"
                     /inference="COORDINATES: protein motif:HMM:NF017044.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pitrilysin family protein"
                     /protein_id="HMZ97471.1"
                     /translation="MMRRQVPHSPRRHRSPGRFFLGLLLLFASLPSTQAQAADIVPSR
                     SVTANGMTVLFLEQHFLPTVEIHALVKVGSAQDPPDKAGLANLTASLLDEGTQTRTSR
                     QIAEQIDFVGGSLEAHAAEDFTTASARVLKKDADLGFALLADVLQHPAFHKQEFERVR
                     TQILGEILSDDDDPGNVAMKAFHQLIFHGHPYSWPAHGAEDTLNKITVADVQQFHARE
                     YLPNQTILVIVGDLTQEQAATLVQTHFGSWKKGAPSPYQLKKPTPIDRKMVQLIEKDL
                     TQSTIVLGHTGISRTNPDYYAVTVMNYILGAGGFSSRLMDSIRDKQGLAYGIMSQFDS
                     RLLPGAFYISLQTRTEVTNQAITGVLTEIKGIRDAPVTDQEINEAKSFIVGSFPLRVD
                     SSAKLANVLAQVEFYNLGLDYFTNYPKAIEKVTKDDVLRVAKQYLDPQHYALVVVGSI
                     AKAKVKQ"
     gene            complement(9743..11137)
                     /locus_tag="PK063_10235"
     CDS             complement(9743..11137)
                     /locus_tag="PK063_10235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pitrilysin family protein"
                     /protein_id="HMZ97472.1"
                     /translation="MPKPSTSHRSSLLRHSVFACSLLSLLLFTSQSSTAHAVEPKEFT
                     LSNDMKVILVEVPKAPVATVQVWYKVGSRNEVMGRAGLSHMLEHMMFKGTAKYPKGTF
                     SRLIRKNGGMDNAFTSQDFTAYFENLAADRVTLALELEADRMQGLILDANEFKTEREV
                     VKEERRLRNEDDPQGALVEALFAQAFMSHPYHWPVIGWFSDLDAMSLDDLQRHYDTYY
                     SPNNATLLVVGDIKAETLLPVIARLFEPIPKGPSPKALTVTEGAQHGERRFLLKREAQ
                     VPFVMMGYRVPNYTSDDSYALNVLESILSHGKSARLYQSLVYEQKTALAVGADYGLMQ
                     ADPGLFYFYAVVKPGEKVEAVEDAVLKEIQRLQTEPPSELELQRAKNQIEAAHIFEQD
                     SNFRQAMLLGEAETIGAGWRKVSQFVERTRAVTPQDVQRVASQYLAADMRTTGTLIPL
                     PPQTQSASPAQPHQ"
     gene            complement(11152..12240)
                     /gene="rlmN"
                     /locus_tag="PK063_10240"
     CDS             complement(11152..12240)
                     /gene="rlmN"
                     /locus_tag="PK063_10240"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: protein motif:HMM:TIGR00048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HMZ97473.1"
                     /translation="MLSHTATRHNLLALTESDMAAFVASLGWPAYRASQILRWLYQER
                     VRTFADMSNLSQKDREHLTSTCSIERATDVHIFASQDGTKKFVLTLTDGKQIECVLIP
                     DEDRLTLCLSTQVGCTLDCGFCLTGTMGLTRNLRAHEILDQVLTAQDHLEADQRLTNL
                     VFMGMGEPLANLDAVADAVTRLTNQTWGLGLSGRRITISTAGLASRIKEVAPLKVNLA
                     ISLNATTDELRHQIMPAANRLHSLQALLAACRDYPLAERDRLTFEYVLLADVNDRPED
                     ATRLIKLLRGLRCKVNLIAFNPFPGSPYRRPSDAAIDQFQNILRRGHVDAYLRRSRGR
                     DVLGACGQLGRIEMPQVPVTLTQIQTRC"
     gene            12419..14584
                     /locus_tag="PK063_10245"
     CDS             12419..14584
                     /locus_tag="PK063_10245"
                     /inference="COORDINATES: protein motif:HMM:NF013618.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HMZ97474.1"
                     /translation="MTAIAESPRPLPVLPPLCVSAEDCFRSALAVNDRTGSPAQREQA
                     TALKIDQLRSVMELFPSTPWAPRARVVLGVLLIEREPAEATKLLRAAQPELPVIDDYF
                     RLWIAESLSKQNEPIQAAELLETIPKIVPDSNLIAKAAYRTGEAWYSANVCFRAVDWL
                     ERAVALADKDQAAPMALSHQADCHLRENRLPEARTALKQLWLRYPQSPEARDAKTRLE
                     GGLGGESWLPTAEEYLIRAQAFLGLSMQAEAVEELRRFLSLAPGHARRHEARLKLGVA
                     YVRLKQYDQARETFRGLVADRVQESAEATVWLARVYLRQSLGDKLIELARSAAQGPLA
                     GDQRAMVHLFAGVWLEDQGKFDEAIGMFRQVAKLGDSASQRAEGLWRAGWAQYRTARY
                     KDAAETFRAVVELHVNGFEPQAMYWAARAEEHGKNANVGDQYARVCQRHAFSYYCQLA
                     ARRTSIPANQPAVGSVERPAGEEIERLPENRRPEIEKHAVYQRGIELKILGFAQEAAR
                     ELGALTEQYSRDQDVLLAFSTMLSEVGAYHPALRVAKVHFREKLERSGLPTAPALWTV
                     AYPTGLVPTIAAQGVTGVDPYLAAAIIREESQYDEKAVSVVGAVGLMQLMPVTANAVA
                     QRYGFPTVGREDLFDQETNIRLGVRYLGLLIEQYSGNLAHAVAAYNAGPIAVNNWIAV
                     HRGRDQDEFVELIPYQETRLYVKRVLRSYGEYRRLHGAS"
     gene            14679..14933
                     /gene="zapB"
                     /locus_tag="PK063_10250"
     CDS             14679..14933
                     /gene="zapB"
                     /locus_tag="PK063_10250"
                     /inference="COORDINATES: protein motif:HMM:NF017786.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA];
                     GO_process: GO:0090529 - cell septum assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapB"
                     /protein_id="HMZ97475.1"
                     /translation="MTLDRLDALEIRIRDLVKLVQDLKRKNTSLEDELRLARERVAVR
                     DDENRRWEQERLDIRSRIEKVLGEIDLLECLDEPKEVAFD"
     gene            14926..15222
                     /locus_tag="PK063_10255"
     CDS             14926..15222
                     /locus_tag="PK063_10255"
                     /inference="COORDINATES: protein motif:HMM:NF017016.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000917 - division septum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HMZ97476.1"
                     /translation="MTKTIDVEIYGQRYTVNGEADESYVKQLAEIVDKQMKQVAAGMR
                     SATPAKLAVLAAFNLAHELMESERRFRQDEADADRRVASLMESIDQQMPSILSR"
     gene            15770..17347
                     /gene="rny"
                     /locus_tag="PK063_10260"
     CDS             15770..17347
                     /gene="rny"
                     /locus_tag="PK063_10260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004521 - endoribonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HMZ97477.1"
                     /translation="MVPISLSVVAYIFIGLVGAVLGAGLYEVLRRRSAITRRAEAEDQ
                     STQIVQSAQREAENLVKEAKLEAKDLVFQARIELEKEQKAKLAEVSNVERRVSQREEG
                     LDRKVSLLEKRDQDVLKREQDLLKREEVLSQKDAACAQALKQHREALERVAGLTAEEA
                     KRQLIQEMDSQARLEAAGLAKRLLEEAKENADREAREIIASSIQRVTRDYVNEATISV
                     VPIANDAMKGRIIGREGRNIRAIEAATGIDLIIDETPEAVIISGFDPLRREIAKVSLE
                     RLMHDGRIHPTRIEEIVEKVKVDIEKLMIEEAEKVIFEVGLSDFHPELVKVLGRLKYR
                     TSYGQNNLYHAREAAYICGIMASELKLDVKLAKRGALLHDIGKAVSHEEEGPHAMLGA
                     EIAKKYGENAKVVNAIAAHHEQVEPICPETVLVAAAEALSAARPGARREALESYVKRL
                     EKLESLATVHKGVQKAYAIQAGREIRVIVKQEDLSDPECFQLSRDLAKKIEQELTYPG
                     QIKVTVIRESRFVDFAK"
     gene            17358..18137
                     /locus_tag="PK063_10265"
     CDS             17358..18137
                     /locus_tag="PK063_10265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HMZ97478.1"
                     /translation="MKVLMIGDIMGEPGRRSVARLLPKLIANHSIDVVVGNGENVAGG
                     FGITPDLVDDLFDLGVSVITTGNHAWDKKEILDVFPREPRLLRPANYPAGVPGRGSYI
                     FTTPGGESLGVLHLMGRAFMPTIDCPFQVAKREVERLKSQVSAIVVDMHAEASSEKMA
                     MGHYLDGLVTVVAGTHTHVQTADEQILPKGTAYITDIGMTGPLHSVIGIKKELAIEKF
                     LTGMPRRFEVASGPTVFCAVLIDLDATLGKAVSIERIRVMD"
     gene            18175..19533
                     /gene="xseA"
                     /locus_tag="PK063_10270"
     CDS             18175..19533
                     /gene="xseA"
                     /locus_tag="PK063_10270"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR00237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HMZ97479.1"
                     /translation="MTGHNLALPLLLSVSDVTRLIRESLEEQFQDVWIEGEISNLRAP
                     SSGHLYFTLKDSQSQLRGVLFRSGALRLRFALQEGLSVIARGRISVYEARGEYQLIVD
                     SLDPKGVGAFQLAFEQLKERLSQEGLFDEARKRRLPSFPSTVGVVTSLTGAAIRDIVA
                     VLRRRCPTVNILIAPVPVQGEGAGASIAEAIDVLSEMPQVEVLIVGRGGGASEDLWAF
                     NEEAVVRAIARSRVPVVSAVGHEIDVTLSDFAADHRAPTPSAAAEAVVPVLAEIMERL
                     DELARRLRRLVDTMLQMQRHRFERSLSVLGETRFRIQAQAQRLDELQDGLTRALTAQL
                     TVLQRELVERRHLLLAQGPRNRIERFLVVIPQLCKRLEQEARRGLMSRRQSVAMQMAA
                     LDALSPLAILQRGFSIVHTISNRKVLRRASEVTVGEAVEVTLAEGQLVCQVEKVMPSS
                     IS"
     gene            19593..19841
                     /gene="xseB"
                     /locus_tag="PK063_10275"
     CDS             19593..19841
                     /gene="xseB"
                     /locus_tag="PK063_10275"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HMZ97480.1"
                     /translation="MAAVKFEYAMARLETIVAELEKGDLPLDDSLKIFEEGIRLSKTC
                     LKMLEDAERKVEILVQEKDGKKRIQAFSPGEDELENPQ"
     gene            19906..20661
                     /locus_tag="PK063_10280"
     CDS             19906..20661
                     /locus_tag="PK063_10280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HMZ97481.1"
                     /translation="MTQKPRPERERLDRALVSRGLVSSREDAARLILAGLVRVDGIVV
                     DKAAKPTMPGALVEVTGPGSPYVGRGGEKLAGALNQFQVDPSGMVCFDVGCSTGGFTD
                     CLLQRGATRVYAVDVGYGQFEWRLRQDPRVVLMERTNVRYLEPGAIAEPIDLIVIDVS
                     FISLTLVLPAVVSHLAASGSIITLIKPQFEVGKGLVGRGGIVRDDALRESTVEKVVSC
                     AAQLGLQSAGRMDSPIEGRKGNREFLAWFQRKA"
     gene            20821..21744
                     /locus_tag="PK063_10285"
     CDS             20821..21744
                     /locus_tag="PK063_10285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HMZ97482.1"
                     /translation="MKVLVTGGAGFIGSHVVDRLLQEGHDVVVVDNLVTGKRKNVPKA
                     AQFYKLDIENPKLERVFRNERPSVVFHLAAQMNVRRSVEDPLFDAQVNVLGTLNVLEQ
                     ASKHGARKVIFSSSGGAIYGEQLAFPAPETHVTQPLSPYGISKLCGEHYLSYYHRMSG
                     IQVVSLRYANVYGPRQDPEGEAGVVAIFIQKMLRGEQAVVNGNGRQTRDFVFVEDVVE
                     ANLMAMGPQVEGVYNVGTGIETSVNDLFRIVVDLTKVEFKEVHGPAKRGEQARSVIDC
                     AKLQRTLGWEPKVELREGLRRTVEFFRDGLG"
     gene            complement(21754..22074)
                     /locus_tag="PK063_10290"
     CDS             complement(21754..22074)
                     /locus_tag="PK063_10290"
                     /inference="COORDINATES: protein motif:HMM:NF012790.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HMZ97483.1"
                     /translation="MSFTITPTELKSRLDKGDKLVLVDVREPWEYAIAKLEGSVLVPL
                     ATLQQSLGKLDRNSEIIAVCHHGMRSADATGFLLQQGFGNVKNLIGGIDAWSVQVDSS
                     VPRY"
     gene            22395..22751
                     /gene="cutA"
                     /locus_tag="PK063_10295"
     CDS             22395..22751
                     /gene="cutA"
                     /locus_tag="PK063_10295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0010038 - response to metal ion [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="divalent-cation tolerance protein CutA"
                     /protein_id="HMZ97484.1"
                     /translation="MQIALAGGGVDAQGSEVVVFITASSNEEAEKLGRMVVESRLAAC
                     ANIVSGIRSIFRWDNQVTVENECLMIMKTTLQRYSELEAVIRQHHSYTVPEIIALPIV
                     AGSVSYLDWIRSETAK"
     gene            22870..23889
                     /locus_tag="PK063_10300"
     CDS             22870..23889
                     /locus_tag="PK063_10300"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013700.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HMZ97485.1"
                     /translation="MSQQTAETSDAYTVVVFRGSSSKPLRFSFPRKFVRKLLILAAIL
                     IVADLLVVSHYVIRTGEVWQLSAFRAEAMGAREQTAAFSAAIDDLKKRLSAMGEVNQR
                     LRVMLGIDTTKPAGDLANGRGGEDGPLPDGKSSVPGNGPASSGLESRQQVSELRENNQ
                     SDLDFSTESIEEATQQVRESLEALVREATQQEEALQSLTQVAEQRSTQWASTPSIWPV
                     RGWVTSGFGPRVSPFTEKPAWHDGLDIGAQANSPVQAPALGRVVTVAFDSKMGNMVKL
                     DHGYGIETVYGHLAKSLVKEGQRVKRGDVVALVGSTGLSTGPHLHYMVKKNGQALDPT
                     KFILD"
     gene            24083..25765
                     /locus_tag="PK063_10305"
     CDS             24083..25765
                     /locus_tag="PK063_10305"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HMZ97486.1"
                     /translation="MTDLEIARSVSHKHIFEVAQTLGIPSEDLIPYGRYKAKIAANFS
                     ARVKSRPLGRYILVTAINPTPLGEGKTTTSVGLSMGLCRLGHNAAVTLRQPSLGPVFG
                     IKGGGTGGGRAQVWPMEDINLHFTGDAHAVSASHNLLSAFVDNHLFQGNALKLDPQRI
                     RWPRTLGVSDRALRDIVLNAEAGPRPGQFVITEASEIMAVLALATDQRDLRQRLGRIL
                     VGLTESGAMTTAEAFGCAGSMSVLLKDALLPNLVQTLEGTPAFVHAGPFGNIAHGNCS
                     VVSDQLALRCADYVITEAGFGSDLGAEKFFNIKCRTSGLRPDAGVVVATLRALKLHGG
                     GGIVKAGTPLPPGLTEVNPAALEKGFANLEQHIANVRAHGVPVVVAVNAFKDDSPKEL
                     EWVCERALAAGAAAAAVSTHWADGGKGAEELARAVVKVAAQGSQFRPLYDATWPIKRK
                     IETIATTIYGAAAVSYSPQAEKDIELAARLGFEQLPICMAKTPLSLSHDPALKGRPSG
                     FTVPIQELRILSGAGFLTAVCSGIQLMPGLPKKPAGERIDIDPQSGEIVGLS"
     gene            complement(25772..26632)
                     /locus_tag="PK063_10310"
     CDS             complement(25772..26632)
                     /locus_tag="PK063_10310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease modulator HflC"
                     /protein_id="HMZ97487.1"
                     /translation="MSKQGFAVAFVGIVIGLLILGASPFYIVDVTQNAIVVQLGKPVR
                     NVTEGGLYLKVPFIEEVTYFDKRLLDYDSNAQDVITQDKKTLLLDNFAKWRITDPLKV
                     YQAFQSQRGALQRLHDIIYSELRVELGRHELAEIVSSARAQLMAVVTQRANEKASVYG
                     IEIQDVRIKRADLPEQNEKAVFSRMQAERERQAKQYRAEGAEEAQKIKSEAEKDREII
                     LAEAYRESEELRGGGDAKAFKIYADAYRQDPHFFEFTRTMEAYRKTLKDKTTILVSPD
                     SEYFRFLKQR"
     gene            complement(26629..27666)
                     /gene="hflK"
                     /locus_tag="PK063_10315"
     CDS             complement(26629..27666)
                     /gene="hflK"
                     /locus_tag="PK063_10315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0045861 - negative regulation of
                     proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease activity modulator HflK"
                     /protein_id="HMZ97488.1"
                     /translation="MVWDPKDPWSKKGDDLDQAFKQAQGQLRNLLPTGGFRNLLLVAF
                     TVFLIWQSAFIVAPDEEGVVKRFGIPVRVVEPGPHMKIPVVESVLQPKVAKLHRVEIG
                     FRTDRQGRQQMIPQEALMLTGDMNILAIEFIVQYKIKSSREYLFNVADIDDTIGKAAE
                     ASMREVIGKSKIDEALTTGKAQIQHDTQELLQHILDEYKTGVQVAAVQLQDVDPPEAV
                     AAAFKDVTNAKEDREKLINQAQGYRNDITPKAKGEAAQLVNQAKGYAQARLNRAQGET
                     NRFLATLKEYNQSKDIISKRIYIETLEDVLPHIDKFVLDGKGGERALPYLPLDRFSKP
                     APTAATQERTP"
     gene            28135..28854
                     /locus_tag="PK063_10320"
     CDS             28135..28854
                     /locus_tag="PK063_10320"
                     /inference="COORDINATES: protein motif:HMM:NF008823.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenite methyltransferase"
                     /protein_id="HMZ97489.1"
                     /translation="MNVDPITSNLYSDQECQGVPADAVAASLGCGNPTALAELQDGET
                     VLDLGSGGGIDVLLSANRVGPKGKAYGLDMTDEMLALARENQRTAGVENVEFLKGEIE
                     NIPLPDGSVDVIISNCVVNLSGEKERVLAEAFRVLRPGGRLALSDIVVRGAVPSEIRK
                     NLELWAGCVAGALEETQYGDLLRQAGFTEIGIEPTRIYQAGDVKELLIGGDLSSDQLV
                     AEVDGKFMSAFIRATKPVSKS"
     gene            complement(29001..30134)
                     /locus_tag="PK063_10325"
     CDS             complement(29001..30134)
                     /locus_tag="PK063_10325"
                     /inference="COORDINATES: protein motif:HMM:NF013543.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter"
                     /protein_id="HMZ97490.1"
                     /translation="MDMSVLTFALVLALAYANGSNDVSKAIATLVGSGVTNYRTAIMW
                     GTAWTVAGAGFATLVAGAMVKTFSNGLLQTGTMLSPSIALAILFGAMLWVLVASRTGL
                     PVSTTHALTGAIVGTGLVAFAGEGLLWAAIGKKIALPLLLSPFLAFGLSLLLHPVMRR
                     AATKWEGSCLCLMPASRALFTVDARGSTRTVFQSTVFGQPVVAVPVQCDRAGLRGLTV
                     GLDTVHWLSSGMASFARGTNDAPKIVAMLLLGSTTATWPSVWFQFAAFGGVAFAMGLG
                     SYLGGLRVTEVLAEKVTRMDHAEGLSANLTTSTLVLCSGWLGLPVSTTHVSSSAIIGI
                     GLLKGFNAVRWTTVRDMVLAWVITLPAAGCFAALAYVLLANFA"
     gene            complement(30275..31312)
                     /gene="arsS"
                     /locus_tag="PK063_10330"
     CDS             complement(30275..31312)
                     /gene="arsS"
                     /locus_tag="PK063_10330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250199.1"
                     /note="Some members of this family are selenoproteins;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenosugar biosynthesis radical SAM protein
                     ArsS"
                     /protein_id="HMZ97491.1"
                     /translation="MALTLVGQHKPLASSAEQLKVLAEIGSCLPFADQLRRSGLSPLH
                     ATGITVLQINVGKLCNQTCRHCHVDAGPDRTERMSRETAEQCIAALAMTDIPTVDITG
                     GAPELNPYFRWLVEQARALNRHVMDRCNLSVLLLPSQADLATFLAAHQVEIVASLPYY
                     RAAQTDAQRGEGIFEKSIEALQLLNSLGYGREGSGLIVNLVHNPVGAFLPAKQEAIEA
                     QFRKELRAKHGVEFNHLYTITNMPVSRFLEFLVESGNYLGYMERLANAYNPAAAGSVM
                     CRYTLSVGWDGMLYDCDFNQMLDLPVQPDAPAHIRDFAPARLHHRQITTRNHCYGCTA
                     GAGSSCGGTVT"
     assembly_gap    31442..31541
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<31542..31875)
                     /locus_tag="PK063_10335"
     CDS             complement(<31542..31875)
                     /locus_tag="PK063_10335"
                     /inference="COORDINATES: protein motif:HMM:NF033788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HMZ97492.1"
                     /translation="MPRHGVANLTTPRQCAAILKAIGDETRLRILESLLLGEKCVTDL
                     THVLRYSQPHVSHHLRILRDAGLVEGHRHGKQVCYRVEPTVQRALKNRGEQVLDFGCC
                     ELRFPTSTL"
     gene            complement(31875..33062)
                     /locus_tag="PK063_10340"
     CDS             complement(31875..33062)
                     /locus_tag="PK063_10340"
                     /inference="COORDINATES: protein motif:HMM:NF025217.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HMZ97493.1"
                     /translation="MAIDDITQKVSDRYARAASTGEQMCCPTGYNFEDLRSFIPDAVL
                     KISYGCGTPAGLDTVQTGETVLDIGSGGGIDCFEATRRVGPTGHVIGIDMTDTMLEIA
                     RQHAPIVAGNLGFPRPNTEFRKGMADAMPVEDASIDLIISNCVINLAPDKRKVFREMY
                     RVLKPGGRFTISDIVSDQVVPQYMVHDSAKWGDCLSGSLQVQDYIGGMVDVGFRAVHQ
                     IKSGAWQSIDGVHFLSVTLTGYKLPDAVTQEAPLYATLCGPFSAVTDESGQQYRRGVP
                     QPLDAKSAQLLRSAPLRSLFLIGPAPITLAAGDPRWCAILPEQTPCVWQGAYAILTGP
                     IIAAEDDDHHQYYRGVPLEICSKTQHVLTQDAYRPHFTIYHRSANVVDGEAVSCSPEG
                     TCC"
     gene            complement(33346..33822)
                     /locus_tag="PK063_10345"
     CDS             complement(33346..33822)
                     /locus_tag="PK063_10345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group 1 truncated hemoglobin"
                     /protein_id="HMZ97494.1"
                     /translation="MSDRLASLAMILGLALTVSACNSMGSPSAGTAATEKSLYDRLGG
                     KTAITAVVDDFVGRVAGDARINGKFANANIPRLKSMLVDQICQASGGPCTYTGRDMKS
                     THAGMGVSSSDFDALVGDLVATLNKFKVPEREKNELLGALGPMKGDIVEKPMASMQ"
BASE COUNT         6961 a         9039 c        10651 g         7316 t
ORIGIN      
        1 actcgccata cattcaatct ccaactgcta ggcgcgggag tctagtgggt ttcagttcaa
       61 aaagcaagtc aagattctga cgtgttgtct gctgtcgaat cattcgaagg gatcggaagt
      121 cagtcacgta agggccaggc cgttgcttga cctctttccg ccaagattcc tatactgcgc
      181 catgtttact tctgctgcgc gccgttctcc ctggattggt cgacttctcc tcggtttcgt
      241 gctgattctg ggcgtgagtt gctccggaaa aaccattcag tataaagacg atcacgaccg
      301 tattctccgg atcgatcagg ccgtggagtc actcaggaaa tcctacgtgg agcgggaccg
      361 gagcgccttg gaggcgttgc ttctcccgtc tgggggcctg gaccaggtgc aacgggatat
      421 ccatagcgat tttgacacct ttcgcgatat tcaattggag ttttccatcg agcgcatttt
      481 gattgaaggc gacaacatcg atgtgtttgt ccattggcag ggccagtgga aacgggatcc
      541 cggcgatgtc ggcacgcgcc aacgaggcca cggccgattg gcctgggtcg ggacacaatc
      601 gattctgctt cgagaggctc aaggcgatct gccgttcggc atggggacac gagccagcct
      661 caatgaagat cccgctcgca gccaacccaa accctagcca tgtcagcccg cagtgcatcg
      721 ccaaaaattg aaacagattt tctcgtcgtc gggagcgggg tcgcgggttt gcgcgcggcc
      781 attgaattga gccgagcggg acgtgtgttg atgctgacca aggggcatcc cctggaaagc
      841 aattccatgt atgcccaggg cggtgtggcc gtcgcactca gcgaagaaga cgatgtcgga
      901 agccatctca ccgatacgtt aaaagccggg catggcctct gtcgccgcga agccgtgcgg
      961 gtgttggtcg aagaagggcc ggagcgaatt caggagctca ttgcctgggg ggccaagttc
     1021 gacaaaatcg gcaaacggtt tgcgtttacc cgcgaagccg cgcacagccg aagccgcatc
     1081 ctccgcgcac ggggggatgc caccggcaac gagatggtgc gcgcgctcat gacctatgca
     1141 gccaggcagc cccgcattca gcgattggat cgacgattta cggtcgacct ggcggtggtc
     1201 gacggacgtt gttgcggcgc catcgtgttg aacgaaatgt cgggggagcg caccgtgctg
     1261 ccggccagcg cggtggtctt gtcgaccggc ggagcgggcc aggtgtacgc gcgtacgacg
     1321 aatccgggca acgcgacggg cgacggcatg gcaatggcgc tgcgggccgg cgcgttgctg
     1381 atggatatgg agttcgtgca attccatccc acctcgctgt acctgccgtc gagtcctccc
     1441 ttcctgctat cggaagccat tcgcggagaa ggcgggcagc ttcggaacat caagggcgag
     1501 ttattcatgc accggtatca tccggacggc gcactggcgc cgcgcgatgt ggtctcccgg
     1561 gcaatctggt cggaaatggc cgccacccgt gcgcgtcatg tctatttgga tgtcacacac
     1621 cttggcgcag cctttgtgaa gcgccggttt cccacgatct acgcgacctg cctgcggtat
     1681 gacatcgata tgacggagga gtggattcct gtctccccca gcgcgcatta catgatgggt
     1741 ggcgtgtgga ccgatgtgca tggcgcaacg acgttgcctg ggttgtatgc ggcgggagaa
     1801 gtggcctgca gtggcgtgca tggggccaat cgattagcca gcaattcatt actggagggg
     1861 ttggtcttcg gtatgcgggc cgcgcaatct gccgtggccc atgcgggcca tttttccgag
     1921 tcagtgcagc tgccgtcact cgaagagctc gagcaggggc gaccgactga gctcgatgat
     1981 ccggaaaagc tccgcagttc gctgcggcgg ttgatgtggg gaaaagtcgg actcgtgcgt
     2041 tcaggagatt ccttgatcag tgcctccgcc cagttggtcc gctggatgcg ccttcttggc
     2101 aaaccctttt cgtcgcgcgc tgcgctcgag gtgaagaaca tggtgcaggt ggcgcgctgc
     2161 atcacggatg ccgccttgtg gcgggaaaat agcgtcggag cccattatcg gtcggacttt
     2221 cccgaagcca agcggcaggg gtggcggaac catagccagt tactgttagg gggtggacag
     2281 gttaacggga tgccgtcgaa tgagcgagac ctcgtccttg cgaccgaggc gcctgtggga
     2341 cgtaagcccg ggaagaagac gtccgggcgt tcatgaggaa ggtgcgatag tacccgagaa
     2401 ctttgaccac atactgccga gtttcaggaa tcggtggaag cccctgatag cgttccaccg
     2461 catgttctcc cgcattgtag gccgccaggg ccaagggcag attgccgtta aatcggtcca
     2521 gcagctgccg taagtatttc gtgcccccgc cgatattctc atccggattg tatgaatccc
     2581 gcacatcgaa gcgcatagcg gtctggggca tgagctgcat caagccgacg gcgcccgcat
     2641 gtgatacggc cagtggatcg aagtctgact ctgttttgat cacggcccga atcaacgccg
     2701 gatgcaggcg atgggcgcgg gagtgccggg cgataaccgg atccaattcg cggtcggaaa
     2761 taacgctgcg cgagcgaggc agttcggaca tcacccgctt atatcgcgga tcattcggta
     2821 cattggtcag ggaaatggtg ccgtttgcgt cgatatattg gtagacctca gcctggacgg
     2881 gtgcgtgtgt cagcaagagt gttgcgtaca gcagaaggag gggcgtggtg cgtttgaatc
     2941 gggccatcgg ggttgaggcg cctgtgcctg tacggtgtgc tttgccgatg atttaaccgt
     3001 agcagtcgac ccccaacctg tcaaaaaccc ttactccttc ctacccctgg aattccctat
     3061 aaggcactga tatcacgggt aatagcggtg tgtgcgtcta aggggctggt gcaagaaacc
     3121 gggttcggct ggcagcgaaa cgcgcctgca ggcggcgagt cagggggccg ggacgaccgt
     3181 caccgatcgg ccaggcgtcg acgcgtgaaa ccggcatgac ttccatgctg gtattggtca
     3241 gaaaacattc atcagcctgg cggagatcgg ccaggtggta atggccttcc tgaactggca
     3301 ggccctcctc ctccgcgaga gtcatgacga tcgctcgcgt gataccgtcc aagataccgc
     3361 agtccaggga tggcgtatgc acggttccgt tcgagataaa aaagagatta ctgatcgtgc
     3421 attcggtcag ttcttcgcgc cagtttagaa atagactgtc aaaagtcccg gccgcgatcg
     3481 attcgcgttt cgccagaatg ttgttcagga aattcgtgga tttgatgtgc ggtgacaggg
     3541 cttcgggcag atttcgcctc gtgttggcaa cggtgagcgt gactccgtcg cgagacagtg
     3601 ccggcgggga gggatggagc accttcgtca aaatgacaac tgtcggacgg ggacagagtg
     3661 cggggtccag cccgatctct ccttcgccgc gtgaaatcgt aatgcggaga taggcatcga
     3721 cccgatcatt gcccacctca ttgcggcgca tggcctcatg gagcaggtcc ggccattgcg
     3781 cgtccggaat cggaatcgtc agcccgatgg cctctgccga gcgccgaagc cgggccaggt
     3841 gttggtcccg catgaaaatg cgagagccgt aggagcgaag cgtttcgtag acgccatcac
     3901 catagagaaa tccgtgatca aacaccgaaa cgacggcttg ttctttcggc acgaatcgat
     3961 cattcagaaa cacccacatc aacggtcagc ctccaggatg tgaagaaaag cgcccgcctt
     4021 ggcgagcgtt tcgtcatatt ctcgatcggg atccgaatcg gccacaatgc cggcccctac
     4081 ctgcaggtag ccgcggtctt tcgtgagaac caacgttcga atgagaatgt tcagatccaa
     4141 atccccgctc caactgaaat agcccagcgc tcccgtgtag aggccgcgcc gcaccggttc
     4201 cagttcgtcg atgatttcca tgcatcgtag tttgggtacg ccggtgatgg tgccgcccgg
     4261 aaacaccgct cggacgaggt cgaaaggcga ggtgcccggt cgcagggttc cgaccacctc
     4321 cgagaccaga tggctgacat gcgagtattg ctcgatggtc ataaactcgt ccacccggac
     4381 cgatccgtat tggcagactt ttcccaggtc gttccgctca aggtccacca acatgacatg
     4441 ttccgctcgt tccttggggc tggccaagag ttcggcacgc atggtcacat cgtgtgactc
     4501 gccgtttccc ctgggcctgg tcccggcgat gggtctggtg ctggcctgcg aggcggttaa
     4561 tcgcacgagt cgttcggggg aactgctgac gagagtgagc tcgggaaatc gcacgagtcc
     4621 cgcaaaggga gaggggttca cgcggcggag acggctgtag agaatgccgg cgtatcggtc
     4681 gcgatccgca gccgaccagc tagcgtccag attgagggtg aagcgatgag aaaggttggc
     4741 ctgataaatg tcgccggccg caatgtagtc ctggcagcgc cggacacgag ccgtgtaggc
     4801 gtcacgcgac tgactgggga caaagctggt ttgtatgggg ccggtcgggg cagggtgagg
     4861 ccgggatatg ctcgtcaggc gagcttccaa ctccgccaat cggtcactgc cttcccggag
     4921 cagtttttcc cgcggttcag cccgaaatcg tgacaacgga gggcagtaca ttagatacag
     4981 ctgatcggtg tggtgatcga ctgcggccac ggtatcgaag aaggccatgt gcaggtctgg
     5041 cagcccgagg tcgtcagaag ccaaggtggg cagtgattca aacgatcgga cgagatcata
     5101 actgaggtac ccgacggccc caccgtaaaa cggcggcaga ccatccggct gagggatcgt
     5161 ggaatcggcg aaggcctgcc ggaacgcatc gaacgcgtag ccatgggcgg ttgtgatgtg
     5221 cccgtcggcc ttcatggaat agtcctgcgc ccggccggtc aatgtaaggt acggatggtt
     5281 gccgaagaac gaatagcgcg cggtagcgtt ggtgccattc ccgctttcca ggagaaagga
     5341 cgggccgtcc gtaataccca ggcgctgata gagttcgaag gcgtccgcgt tcggcagcgg
     5401 tcgaaccacg accagtggtt gtggagggcc gttgagaaat gcctggtgcg atacagcagt
     5461 catgagggtg tcagtcacgg tgtcgtaccc gagaaaaaga ctataccgca tcgtgaggcc
     5521 gggtcatagc aggccaactt cttgacaagt ccccagcgaa tttgcttgaa tggcgcgccc
     5581 gccgatgggt gcactctctc cgactgtgct gaggagtgcc gcgcgtgagc acgtgatgcc
     5641 cccctctcag gatccgttat atgcggggct cgggcaagct gtccggatcg ggacggaact
     5701 gctcgctgcg ttgattgtcg ggggcggatt gggctgggtg gtcgatacgt atctgctgga
     5761 ttccaatccc tgggggttgg tcgcaggatt gggcctgggt gccgctgccg gtatccgcaa
     5821 tgcctatcga tcggctcaac gatggcagag ttaacctgaa tcgtctgact cacaaaggat
     5881 catcgtggaa gaaagtccgt tacatgcgtt tgaattgcac gacctgattc cgctcgtgcc
     5941 cgccggcgtc gatatctcca tcaacaaagc ggtgattctc atgtgggtgg tggtcgggct
     6001 ggttgccttt ctcatgatct ctgccgccgc cgcacgtaag ttagtgcccg gcaagttgca
     6061 gaacatggcc gaattgatcg tcgagttcat tcgcggaatt attttggaca ccatgggtga
     6121 agcgggaatg aaatatttcc ccctgatcgc cacgctgttt ctctttatcc tcttcgcgaa
     6181 tctgctcggc ttgattccgg gttcctacac cgtcacgagc cagatcatcg tcaccgcggt
     6241 atttgcggtg gggatctatg gactgagtct ggttctggga ttttcgcttc atggaatgaa
     6301 attcctgggt attcttgtgc cgcctggcac accgggttgg ttgctgccgc tcatgattcc
     6361 gattgagttg atcagtcaac tggcgcggcc catttcactg gcggtacggt tgttcgcaaa
     6421 tatgacggcc ggccacgtga ttttaggcgt gctgttcgga ttggctatca gtggtggatt
     6481 gctgatcgga tggttgccgt ttgccttcac gattgcgatg aatggtctcg aagtcggcat
     6541 tgcgtttatt caagcctata tcttcaccgt gctgagctgt gtctatttag gggatgccgt
     6601 gaccttgcac ggtcatagcg agcacgcaca ctaggtcgag tggtctataa acggaggaga
     6661 ggacacacaa tggatgcagc agcagcagcg ttggtcggca tggggttggc ggcggcaggt
     6721 tttgccggag ccggcgtggg aatcgggtac atcttcggaa aaatgattga ggccgtggcc
     6781 cgccagccgg aagccgaagg tcgcgtcggg aagtacatgt ggatcggttt cgcgttggtc
     6841 gaagctatcg ccttgtacgg gctggtcatt gcgttcatca tcatgggctt gcgcaagtaa
     6901 gcgcaccgac ggtcgagccc tgatgctggg gacaggcccg gctcagaacc ctcaactcat
     6961 tgggtaacag actatgcctc aatttgaatc acatttcttt tcgtcgttga tcttctggga
     7021 gattctctcc ttcgggattc tcttcttctt gctctacaag tacgcgttcc cgagcttgtt
     7081 gggcatgctg gaggagcgtg agaaaaagat caaggacagt ctcgatcaag ccgaacgcca
     7141 tcgttcggag gccgagcgca agctcaagga atatgaagcc aagctggcca ccgcagccaa
     7201 agacgcggag gcactcttgg ctcaggccaa agagcgcgcg gcacggttga tggaagagaa
     7261 cgaacagcgc atgacggcgg atgcagagcg gatcaagggc gacgcgactc gtgagatcga
     7321 gaccgaacgt cgtaaggcca ttcaggacat ccgctcgcaa acgacggatt tagcgatgat
     7381 ggttgcggag aaagtggtcg ggcgagcatt gaccgacggg gatcaccgtc gtctggcaga
     7441 tgaagccctg gacgcacttg cgaagaccta ccagagccgg aactaagttt ctgacgccgg
     7501 gggggtgaga cttacacctc cctggcgata tccttccagg tccaacgtca cgaagcgata
     7561 gcctatctgt ttcagactct cgacgagctg ttcgcggcac cccgcttcca acaatttcgg
     7621 cagctcctct acggccaact caatcctcgc caggtccccg tagtcgcgta cccggcagtg
     7681 gcgaaaacct ccctggatca aagccgcttc cgcctgctcc acgcgcgaga gcgtgcttcg
     7741 agtgatcgtg atgcctctcg ggacgcgtga ggagaggcag gcagccgcag gcttgtccca
     7801 attggagagg tgcagttcgc gggcagcttc gcgaatgtcg gcttttgtga atccggcttc
     7861 caataatggg ctgcgcaccc catgttcccg ggcggccttc agaccggggc gatcgtctcc
     7921 taagtcgtca acgttggtgc catccacgat acacgccgtc gcatcttcgc ttctcaattt
     7981 acccaagagg gaatagagat cggtcttgca gtggtagcag cgggtggcat cattgcggac
     8041 gaactgcggg atttccagtt gatccgtctc gaccacccga tggcgcgctc cgatttccgt
     8101 cgcgagttgc tgagtcagcg cgagttccga tgcgggaagc gtgggtgaga cggcggtgac
     8161 tccggtggcc tgcattccca attcatcatg cgccagtttg aggaccaacg tactgtcgat
     8221 gcctccggaa aaggccacga tcaccgagcc catctctcga aggaggtgcc gtgcccgtga
     8281 aatcttttcg atcagtggtg tgctggagac catggggagt ccgacgtgtt gcgcggtcgt
     8341 cgagtcgggc aaggaaggag ctattgtttc actttggctt tcgcaatcga accgacgacg
     8401 accaaggcgt aatgttgagg atcgagatac tgtttcgcca cgcgaagaac atcgtccttc
     8461 gtgacctttt cgatggcttt gggatagttc gtaaaataat ccaatcccag attatagaac
     8521 tccacctgtg cgaggacgtt ggccagcttg gcgctggaat cgacccgcag agggaagctg
     8581 ccgacgatga aggacttcgc ttcattgatt tcctgatccg tgaccggggc gtcgcgtatc
     8641 cctttgattt cagtcaggac cccggtgatg gcttgattcg tgacctcggt tctggtctgg
     8701 aggctgatgt agaacgcgcc cggcagcagg cgggaatcga attggctcat gatgccgtac
     8761 gccagtccct gcttgtctcg aatggagtcc atgagccgtg aagagaatcc cccggcgccc
     8821 aaaatgtagt tcatgaccgt gacggcgtag tagtccgggt tcgtccggct gatgccggta
     8881 tgccccagca caatggtcga ttgcgtgaga tctttttcaa tcaactgcac cattttccgg
     8941 tcgatcggcg tcggcttttt aagctggtag ggcgatggcg cgcccttctt ccacgagcca
     9001 aagtgggttt gtaccaatgt ggctgcttgt tcctgcgtca ggtccccgac aatgaccaga
     9061 atcgtctgat tcggtaaata ttcccgcgcg tggaactgct ggacatcggc cacggtgatt
     9121 ttgttcagcg tgtcctcggc gccatgcgcc ggccagctat agggatggcc atggaaaatc
     9181 aattgatgaa aggccttcat ggccacattg ccgggatcgt cgtcatcgct gagaatttca
     9241 ccgaggatct gggtgcgaac ccgttcgaat tcctgtttgt ggaaagcggg atgttgcaac
     9301 acatcggcga ggagggcaaa cccaaggtcc gcgtcttttt tcagcacgcg cgcagatgcg
     9361 gtggtgaaat cttccgccgc atgggcttca agagagcctc ccacgaaatc gatctgctca
     9421 gcaatctgcc gggatgttct ggtttgagtg ccttcgtcca ggaggctggc tgtgagattt
     9481 gccaggcccg ctttatccgg cggatcttga gccgacccca ccttcaccaa ggcatgaatt
     9541 tccaccgtgg gaagaaagtg ttgttcaaga aacaggacgg tcatgccgtt tgccgtcacg
     9601 gagcggctcg gaacgatgtc ggcggcctgt gcttgtgtgc tcggcagaga ggcaaacagc
     9661 aggaggagtc cgagaaagaa ccggcctggt gaccggtggc gtcggggtga atgcggaacc
     9721 tgtcgtcgca tcatctatgt gctcactggt gcggttgggc cggcgacgcc gattgagttt
     9781 gcggcgggag cggaatcaat gtcccggtgg tgcgcatatc ggcggccaga tattgcgagg
     9841 caacacgctg gacgtcctgt ggcgtgacgg cacgggtacg ttcgacgaac tgactgactt
     9901 tacgccatcc agccccgatc gtttctgctt cgcccagcag catggcctgg cggaagttgg
     9961 aatcctgttc gaaaatgtgg gcggcttcga tttggttttt ggcgcgttgg agttcgagct
    10021 cactgggtgg ctccgtttgc agccgctgaa tctctttcag taccgcgtcc tccacagctt
    10081 cgactttctc gcctggtttc acgaccgcat aaaaataaaa taagccagga tcggcctgca
    10141 tcaagccgta atccgcgccc acagccaagg cggtcttctg ttcatagacg agactttggt
    10201 acagccgcgc gctctttccg tgggacaaaa tcgactcgag cacgttcaac gcataggaat
    10261 cgtcgctcgt gtagttaggc acccggtacc ccatcatgac aaagggtact tgggcttcgc
    10321 gtttcaacag aaaccgtcgt tcgccgtgct gcgcaccttc ggtgacagtc agggctttag
    10381 gcgaaggacc tttgggaatc ggttcaaaga gtctggcaat gacgggaagg agcgtctcag
    10441 ccttgatgtc gccgacgacg agcagggtcg cgttgttcgg cgaataatac gtatcataat
    10501 ggcgctgaag atcgtccagg ctcatggcat cgaggtcgga aaaccacccg atcaccggcc
    10561 aatgatacgg atggctcatg aaggcttgtg cgaacagcgc ttcgaccagc gcgccctggg
    10621 gatcatcctc attgcgaagc cgacgttctt ccttgacgac ttcccgctcg gttttgaatt
    10681 cgttcgcatc aagaatcagt ccctgcatcc ggtctgcttc aagctcaagg gccagggtca
    10741 cgcgatcggc ggccagattt tcaaagtacg cggtaaagtc ctgactggtg aaggcgttgt
    10801 ccattccgcc gtttttgcgg atgaggcggg aaaacgtccc cttgggatat ttcgcggtgc
    10861 ctttgaacat catatgttcc agcatgtgcg agagcccagc gcggcccatc acctcattgc
    10921 gggaaccaac cttgtaccag acctgcacag tcgccacggg agccttcggg acctccacga
    10981 ggatgacctt catgtcgttg gacagcgtga actctttcgg ctcgacggca tgggcggtgg
    11041 agctctggct ggtgaacagc aggaggctta gaagcgaaca agcaaatact gaatggcgaa
    11101 gcagggatga tctgtgggat gtgctcggct taggcatgta cgaagatcat gctaacaacg
    11161 ggtctgaatc tgtgtcaagg taaccgggac ttgcggcatc tcgattcgac ccaactggcc
    11221 gcaggcgccc aggacatcgc gaccgcgact gcgccgcagg tacgcatcca cgtggccccg
    11281 gcgcaggatg ttctgaaact ggtcaatagc ggcatccgac gggcgtcgat agggactgcc
    11341 gggaaaggga ttgaaggcga tcaagttgac cttgcagcga aggccgcgca gcagtttgat
    11401 caatcgggtc gcatcctcag gccgatcgtt cacgtccgcc agcaggacgt attcaaaggt
    11461 aaggcgatcg cgttcagcca ggggatagtc gcggcaggcg gcaagcaggg cttggagcga
    11521 atggagccgg ttcgcggccg gcatgatctg gtggcgcaac tcatcggtgg tggcgtttaa
    11581 tgaaatcgcc aggttgacct tcaagggggc cacctctttg attcgcgacg cgagacccgc
    11641 agtggaaatg gtgatccggc gacccgacaa tccgagtccc catgtttgat tcgtcaggcg
    11701 tgtgaccgcg tcggctacgg cgtcgaggtt ggccagcggc tcgcccattc ccatgaacac
    11761 caggttcgtc aggcgttggt cggcttccaa atggtcctgg gctgtcagga cctggtcgag
    11821 gatttcatgg gcgcggagat tgcgcgtgag ccccattgtg cccgtcaggc agaatccgca
    11881 atcgagcgtg cagccgacct gcgtggacag gcacagtgtg aggcggtctt cgtcgggaat
    11941 gaggacgcat tcaatctgct tgccgtccgt cagcgtgagc acaaatttct tcgtgccgtc
    12001 ctgcgaggca aagatgtgga catccgtggc tcgctcgata ctgcaggtgg aggtgagatg
    12061 ctcacggtcc ttctgcgaga ggttgctcat gtcggcaaag gtgcggaccc gttcctgata
    12121 gagccagcga aggatttggg aggcgcgata ggccggccag cccagcgagg ccacgaatgc
    12181 ggccatgtcc gattcggtca acgccagcag gttatgacgt gtcgcagtgt gtgagagcat
    12241 gacggagcct agcacaggga aaaaacttgt gacaagcaag gcgaacctgg tcgcgtttct
    12301 atggcgttac gctataatga tgtcggttca ccttctgctc aggggcattg tgcgcggact
    12361 tccttggcgg accagtatag cggcattcgc cgtgtgtctt tttctgtcga gtgtattctt
    12421 gacggcgata gcggagtccc ctcgtccgtt gccggtgctt cctcctctct gtgtctccgc
    12481 tgaagattgc tttcgttccg ccctcgccgt caatgatcga accggttccc ccgcccagcg
    12541 ggagcaggcg acggcgctca aaatcgacca gctgcgatcc gtgatggagt tgtttccgtc
    12601 gactccatgg gctccacgag ctcgggtcgt gttaggcgtc ctgctcatcg agcgagaacc
    12661 ggctgaggcc accaaacttc tccgggccgc tcagccggaa ttgcccgtga tcgacgatta
    12721 ttttcgtctt tggattgcgg agtcgttgtc gaaacagaac gaaccgatcc aagccgccga
    12781 actgctggaa acgattccca agattgtgcc ggattcaaac ctgatcgcaa aggcggccta
    12841 tcgaacagga gaggcctggt acagcgcgaa tgtatgtttc cgcgccgttg attggttgga
    12901 gcgtgccgtg gcgctagcgg ataaggatca ggcggctccg atggccttat cccaccaggc
    12961 ggactgtcat cttcgcgaga accggctgcc ggaggcccgc acggcgctga agcagctctg
    13021 gctccgttat ccccaatcac cggaagcccg cgacgcgaaa acgcgattgg agggcggtct
    13081 gggaggagag tcttggctgc cgactgccga ggaatatttg attcgagcgc aggcgtttct
    13141 tggactctca atgcaagccg aggccgtgga ggagttgcgg cggtttctct cgttggctcc
    13201 cgggcatgcc cgccggcatg aggctcgcct caagttgggg gtcgcctatg ttcggctcaa
    13261 acaatatgac caggcccgtg aaacattccg cggcctcgtg gccgaccgag tgcaggaatc
    13321 agcggaagcc acggtatggt tggcccgggt gtatttgcga caaagccttg gcgacaaact
    13381 catcgaattg gcacgatcgg cagcccaggg tccactagcc ggtgaccaac gggcgatggt
    13441 gcatctcttc gccggcgtgt ggttggagga tcagggcaag ttcgatgagg cgatcggcat
    13501 gttccggcag gtcgcgaagc tgggggattc agccagccaa cgggctgaag ggctctggcg
    13561 ggccgggtgg gcgcaatatc ggaccgcccg gtataaggat gccgcggaga ccttccgtgc
    13621 cgtcgtggag ttgcacgtca atggctttga acctcaggcg atgtattggg cagcgagggc
    13681 cgaggagcat ggaaagaacg cgaacgtcgg agaccaatac gcgcgggtct gtcagcgcca
    13741 tgcctttagt tattattgcc agctcgctgc gcgacgaacg tcgataccgg cgaaccagcc
    13801 ggcagtggga tcggttgaac ggccggccgg ggaagagatc gaacggttgc cggaaaatcg
    13861 gcgtcccgaa atcgaaaagc acgcggtgta tcagcgggga atcgagctca aaatcctggg
    13921 gtttgcccaa gaggcggcgc gggagctggg agcgctgacc gagcagtaca gtcgcgatca
    13981 ggatgtgctg ctagcctttt caacgatgct cagtgaagtg ggggcgtatc atccggcctt
    14041 acgcgtagcg aaagtgcatt ttcgggaaaa gttagagcga agtggattgc cgacggcacc
    14101 ggccctatgg actgtcgcct atcccactgg cctcgttcca acgatcgccg cccagggcgt
    14161 gaccggcgtc gatccctatc tcgcagccgc tatcatccgg gaggaaagcc aatacgatga
    14221 aaaggcggtc tcagtggtgg gggcggttgg cttgatgcag ctcatgccgg tgacagccaa
    14281 tgcggtcgcg caacggtacg gattcccgac ggtcggccgg gaagacttgt ttgaccagga
    14341 aacgaatatc cgcctcggag tgcggtatct ggggctattg atcgagcagt acagcggcaa
    14401 tcttgcccat gcggtcgcgg cctacaatgc cgggccgatt gccgtgaaca attggatcgc
    14461 agtacatcgg ggacgtgatc aagacgagtt cgtggagctc attccgtacc aggaaacgcg
    14521 attgtatgtg aagcgggtct tgcgcagtta cggagaatat cgccggctcc acggcgcgtc
    14581 atgacgagac cggttttctt gacaaggggg catgaacttt ctatatttcg cccccattaa
    14641 ccatcgtgtg tgaccatcac tttgaatgag gaaataccat gactttagat cgtctcgatg
    14701 cgctggaaat tcggattcgt gatctcgtga agctggtgca ggatctcaag cggaagaaca
    14761 cgtcgttgga ggacgagctt cgcctggcgc gtgagcgggt cgcggtgcgc gatgatgaaa
    14821 accggcgctg ggagcaggaa cgtctcgata tccggtcccg gatcgaaaag gtgctcggcg
    14881 aaattgattt gctggagtgc ctggatgaac ccaaggaggt ggcgtttgac taaaaccatt
    14941 gacgtggaga tctatggcca gcggtatacc gtgaatggtg aggccgacga atcctacgtg
    15001 aagcaactcg ccgagattgt tgataaacaa atgaaacagg tggcggccgg tatgcggtcg
    15061 gccaccccgg ccaaattggc cgtgcttgcc gcatttaatc ttgcccatga gttaatggaa
    15121 tcggagcgga ggtttcggca ggatgaagcc gatgccgacc gccgcgtagc ctccctcatg
    15181 gagtcgatcg atcaacagat gccgtccatc ttgtcgcgtt gagtttcacc ttgctttcac
    15241 tgcactcctt tgttatcgtt tcttcgttgt gttgacctga gggtcaacaa gagcaggaga
    15301 ggaaaggacg cttcgaataa ggacggaaaa tctgacgacg gtatttgagc tctaaacata
    15361 tggaatcgct ggtttttgtg ctgctgttca gtgtggtcgt gattgcatgg atgagtcagg
    15421 gggctcggcc ctatgtgccc gtgcgacagg tgtgtcatca accaacgccg atgttggaga
    15481 accagaggct caccaggatc tgggggcatt ccccgtggct tgaatatgca acagttcgaa
    15541 caaggcggct cggctctgtt cgtgcacgag ctcacgtaag aaacgatcta ggtcgaggcc
    15601 gaccacgcct ctacttggac tagcgacggc gattccgcac ttcgtgttcg actggctcaa
    15661 gtagtcaggt tccttcctgt ccagctattc cttcacttcc tgctcccttt accactggct
    15721 gcgattattt gcagggtgac agtgtgcctg tcccactgcc gtaagggagg tggttcccat
    15781 ttctctcagc gttgtagcgt acatttttat cgggttagtt ggagcggtct tgggcgccgg
    15841 tctgtatgaa gtgttgcgcc gccggtctgc cattacacga cgggccgagg ctgaggacca
    15901 gtccacgcag atcgtgcagt cggcccagcg tgaagccgaa aacctcgtga aagaggccaa
    15961 gcttgaagcc aaggacctcg tgtttcaagc acgaatcgag ctggaaaagg aacaaaaagc
    16021 gaagcttgcc gaggtctcga atgtggagcg gcgggtgtct cagcgcgaag aggggctgga
    16081 caggaaagtc agcctgcttg agaagcgtga tcaggatgtg ctcaagcggg agcaggatct
    16141 cctgaagcgg gaagaggtgc tctcgcagaa agatgcagcc tgtgcacagg cgctcaagca
    16201 gcatcgcgag gcgttggagc gggtggccgg actcactgcc gaagaagcca agcggcaatt
    16261 gattcaggag atggatagtc aggctcgctt ggaggctgct ggtttagcca agcggttgct
    16321 cgaggaagcg aaagaaaacg cggatcgtga agcgcgggag atcatcgcct cttcaattca
    16381 gcgcgtgacc cgtgattatg tgaacgaggc cacgatttcg gtggtgccga tcgccaatga
    16441 tgccatgaag ggccggatta tcggccgtga agggcgaaac attcgcgcta tcgaggcggc
    16501 cacgggtatc gatctcatta tcgatgaaac gcctgaagcc gtgattatct cgggcttcga
    16561 cccccttcgc cgcgaaattg ccaaggtgtc gctcgagcgg ctcatgcacg atggccggat
    16621 tcatccgacc cgcattgagg aaatcgtcga aaaagtaaag gtcgatatcg agaagctgat
    16681 gatcgaagag gcggaaaagg tcatcttcga agtcggcttg tcggatttcc atcccgagtt
    16741 ggtcaaggtg ctgggacggc tcaaatatcg aacgagctac ggacagaaca atttgtacca
    16801 tgcgcgggag gcggcctaca tttgcgggat catggcctcc gagttgaaac tcgacgtgaa
    16861 actcgctaag cgaggggcgc tgttgcacga tatcggcaaa gcggtgagtc acgaggaaga
    16921 ggggccgcat gccatgctcg gcgcagagat cgccaagaaa tacggcgaaa acgccaaggt
    16981 ggtcaatgcc attgcggcgc accatgagca ggtggagcct atttgccccg agaccgtgct
    17041 ggtcgcggcg gcggaagcgc tctcggcggc gcgtcccggc gctcgtcgtg aagcgttgga
    17101 gtcctacgtg aagcggttag aaaagctaga gtcgctggca accgttcaca agggcgtaca
    17161 gaaagcctat gcgattcagg ccggacggga aattcgcgtg atcgtcaagc aagaagatct
    17221 ctcggatccg gaatgtttcc agctctcccg ggatctggcc aagaaaatcg aacaggaact
    17281 gacgtacccg gggcaaatca aggtcacggt gatccgggag agccggttcg tcgattttgc
    17341 gaagtgagcg acagcgtatg aaagtcctga tgatcggaga tatcatgggc gagcctggac
    17401 gacggtccgt ggctcgcctc ctgccgaagc tcattgccaa tcattccatc gatgtggtcg
    17461 tcggcaacgg cgagaacgtg gccggtggat tcggcattac gcctgatctg gtggatgatc
    17521 tctttgacct cggggtttca gtcatcacca cagggaatca cgcctgggat aagaaagaaa
    17581 ttttagacgt gtttcctcgg gaaccgcgtc ttctgcggcc tgcgaactat cccgcggggg
    17641 tgcccgggcg aggtagttac atcttcacga cgccgggcgg ggagtcgctg ggggttctcc
    17701 atctcatggg acgggcgttc atgccgacca tcgattgccc gtttcaagtt gccaaacggg
    17761 aagtcgagcg actcaagtcg caggtgtcgg ccatcgtggt tgatatgcat gccgaagcct
    17821 cgtctgagaa gatggcgatg ggacactacc ttgatgggct ggtgacggtg gtggcgggaa
    17881 ctcatacgca cgtgcagacg gcggacgagc agattcttcc caagggaacg gcctacatca
    17941 ccgacatagg catgaccggt ccgttacatt cggtgatcgg tatcaaaaaa gagctcgcga
    18001 ttgaaaagtt tctcacgggg atgccgcgcc ggtttgaggt ggcgtcgggc ccgacggtgt
    18061 tctgcgccgt cctcattgac ctggatgcca ccctcggcaa agcggtgtcg atcgaacgta
    18121 tccgagtgat ggattgatct gtccgctgac ttattccctt ccgctcggtg agccatgacc
    18181 gggcacaatc ttgcgctgcc attgctgctg tccgtgtccg atgtgacgcg gctcatccgg
    18241 gagtctctgg aagagcaatt tcaggatgtc tggatcgagg gcgaaatctc gaatcttcgt
    18301 gcgccgtctt ccggccacct ctacttcacg ctgaaagata gccagagcca acttcgcggc
    18361 gtgttgtttc ggtccggagc cttgcggctg cggtttgcct tgcaggaagg cttgtctgtc
    18421 attgcgcgcg ggcgcatctc cgtctacgag gcccgtggcg agtatcaatt gattgtcgac
    18481 tcgctcgacc ccaagggcgt cggtgcgttt caactggcat tcgagcagct caaggagcgg
    18541 ttgtctcagg agggattgtt cgatgaggcg cgcaaacgga ggttgccatc atttccttcg
    18601 acggtcgggg tggtcacctc gctgaccggt gcagcgattc gggatattgt agccgtgctt
    18661 cgccgccgtt gccccaccgt caatattctc attgccccgg ttcctgttca gggcgaaggc
    18721 gccggggcgt ccattgccga ggcgatagac gtcttgagtg aaatgccgca ggtagaggtg
    18781 ctgatcgtcg gtcgtggcgg cggcgcgtcg gaagatttgt gggcgttcaa cgaagaggcg
    18841 gtggttcgcg ccattgctcg atccagggtt ccggtggtct cggctgtggg gcatgaaatc
    18901 gatgtgacgc tctcggactt tgccgcggac caccgtgctc ccacgccctc tgcggcggct
    18961 gaggcggtgg tacccgtatt ggccgagatc atggaacggt tggatgaatt ggcccggcgt
    19021 ttgcgccgcc ttgtggatac catgctgcag atgcagcggc accggtttga gcgatcgctc
    19081 agcgtgttgg gcgagacacg gttccggata caggcgcagg ctcagcggct cgatgaattg
    19141 caggatggat taacgagggc cttgaccgca cagctgacgg tgctgcagcg cgaactggtg
    19201 gagcgccgac acctcttgct tgcgcaggga ccgcgcaatc ggattgagcg gttcttggtg
    19261 gtcattcctc agctctgcaa gcgcttagag caggaggctc gccgcgggct catgtccagg
    19321 cggcagtcgg tggccatgca gatggccgcg ctcgatgcgc tcagtccgtt agccatttta
    19381 cagcgcgggt tcagcatcgt tcacacgatt tctaatcgga aggtcttgcg ccgggcctcc
    19441 gaggtgacag tcggagaggc cgttgaggtg acactcgccg aaggacaatt ggtttgtcag
    19501 gtcgagaagg tcatgccctc gtcgatatct tgacccgacc aggagcgcag gcaataatgt
    19561 tttgattgac ggatgagcaa aagggagttg tcgtggctgc cgtaaaattc gaatatgcga
    19621 tggcgagatt ggagacgatc gtcgccgaac ttgaaaaggg agaccttcct ctcgacgatt
    19681 cactgaagat tttcgaggaa ggcattcggt tgtcgaagac ctgtctgaag atgctggagg
    19741 acgccgaacg gaaggtggag attctggtgc aagagaaaga cggcaaaaag cgcattcaag
    19801 cgttttctcc cggtgaggat gagttggaga acccacagta gtcgtttggc tctacgcggg
    19861 ccacgatgtg gcctgcccat catcgtcgaa cctcctctca cacgtatgac tcagaaacct
    19921 cgcccagaac gggaacgcct ggatcgtgcc ctggtcagcc gtgggcttgt atccagtcgt
    19981 gaggatgcag ccagattgat cctggcgggg ctggttcgtg tggatggcat cgtcgtcgac
    20041 aaggcggcga aaccgacaat gccgggtgcg ctggttgaag tgaccgggcc cggatcaccc
    20101 tacgtggggc gtggaggaga aaagctggcc ggcgcgctga atcagtttca ggtcgatccg
    20161 agtggaatgg tctgtttcga tgtgggatgt tcgacgggag ggtttaccga ttgtctgctg
    20221 cagcgaggcg ccacccgtgt gtatgccgtc gatgtggggt acggtcaatt tgagtggcgt
    20281 cttcggcagg atccgcgagt ggttcttatg gagcggacca acgtgcggta cctcgagccg
    20341 ggtgccatcg cggagccgat cgatctgatc gtgatcgacg tctcattcat ttccctcacg
    20401 cttgtattgc ctgcggtcgt ttcccatctt gccgcgtccg gttccattat cacgctgatc
    20461 aagccgcaat ttgaggtggg gaagggactg gttggccggg gagggattgt gcgggacgac
    20521 gcattgcgag agtcgacggt ggaaaaggtg gtgtcttgtg cggcgcaact cggcttgcag
    20581 tcggcaggcc gcatggattc tccgatcgag ggccgcaaag gcaatcgcga attcctcgca
    20641 tggtttcagc ggaaggcctg aatccggccc cgtaggccgt cgcaggatgg tcctggccaa
    20701 tggccttctg gcaggggcag gacgaaaaca ctttgaggaa gcggacagaa ggtgtaggct
    20761 gagttccgat acagtccgga tgctgttgtt acggctgatg aaggagaggc gaggagacgt
    20821 atgaaagtct tggtgaccgg aggggctgga tttatcggat cacacgttgt ggatcggttg
    20881 cttcaagagg ggcacgatgt cgtggtggtg gataatctcg taacgggcaa gcgcaaaaac
    20941 gtgcccaagg cggcgcagtt ctataagctg gacatcgaaa atcccaaact ggagcgggtt
    21001 ttccgcaatg agcggccttc tgtggtcttt cacctggcgg ctcagatgaa tgtgcggcgg
    21061 tccgtcgaag atccgctatt cgacgcccag gtcaatgtgc tggggacgtt gaatgtcttg
    21121 gagcaggcat ccaagcatgg tgcgcgaaag gtcatttttt cgtcatccgg cggggcgatc
    21181 tatggagagc aattagcctt tcccgcaccg gaaacgcatg tcacgcaacc gctgtctccc
    21241 tatgggatca gcaaattgtg cggggagcac tacctgtcct actaccaccg gatgagcggc
    21301 atacaggtgg tgagcttgcg gtatgccaat gtgtacggac ctcgccagga tcctgaaggc
    21361 gaagcgggcg tcgtggccat tttcattcag aaaatgctgc gcggggagca ggcagtcgtg
    21421 aatgggaatg gtcgccagac ccgtgatttt gtgtttgtgg aagacgtcgt cgaagcaaat
    21481 ttaatggcga tgggccctca ggtagagggt gtgtacaatg tggggaccgg cattgagact
    21541 tcggtcaatg acctgttccg gatcgtcgtg gacctgacca aggtggaatt taaagaagtg
    21601 catggtccgg ccaagcgcgg tgagcaagcg agaagcgtca ttgactgcgc aaaactccag
    21661 cggacactcg gatgggagcc gaaggtcgag ttgcgagaag gcttgcgacg aacggtggaa
    21721 ttttttcgag atggactcgg gtagcctccc gggctagtac cgaggcacgg acgaatctac
    21781 ctggacggac caggcgtcga tacctccgat taagtttttt acgttcccaa acccttgctg
    21841 taagagaaat cccgttgcat ccgcgcttct catcccgtgg tggcaaaccg cgataatttc
    21901 tgagttgcga tctagtttcc ccagggactg ttggagcgtg gccagtggta ccaggactga
    21961 cccttccaac ttggcaatgg cgtattccca gggctcacga acatcaacga gcacaagttt
    22021 gtcaccttta tccaacctcg acttgagttc tgtgggtgta atagtaaagc tcatcaatat
    22081 acctccctct ggactgaatg gtcggatcat aaggaggcag aaaaggggtg tcaaccctgg
    22141 tgaggccttg ctggggagtg tctctcaagg ttcgacgcgt tcagtccgaa gaagagcagc
    22201 ggtatcagat aagccggacg gttggttcaa cagtatgggg ccgggaaaat cctgcatcgc
    22261 aggatggccg ttttttgttt ctctgtgcaa ttcctgccca gattggtagg agcgttgtgc
    22321 tggaaaatgt gggaaaatat cccgtaagtg gttgatttat atcagcatgt ctgtgattgg
    22381 cgacaggtat gggcatgcaa attgctttag cagggggagg cgtggacgcg caaggttccg
    22441 aggtcgtggt attcatcact gcctcgtcaa atgaggaagc agagaaacta ggacgaatgg
    22501 tcgtcgaatc cagacttgcc gcctgcgcca acatcgtgag cgggattcgc tcaatttttc
    22561 gatgggacaa tcaggtcact gtcgagaatg aatgcctgat gatcatgaaa acgaccctgc
    22621 agcggtattc tgagctggag gccgtgattc ggcagcacca cagctatacg gtcccagaaa
    22681 tcatcgcgtt gccgatcgtc gcgggctcgg tttcgtacct ggactggatc aggagtgaaa
    22741 ctgctaagta gctgattcta atatgtaaaa ttttgaaaac taagggttga ccaccgggct
    22801 tgagatgggt acactgcaaa agtcggtggt tgcggtttga aagtgaatcc gtgaagggga
    22861 gaccagccta tgagccaaca aacggctgaa acaagtgatg cctacactgt cgtggttttt
    22921 cgaggatcat cctccaagcc actccggttt agtttcccac ggaaattcgt ccgcaagctc
    22981 ttgatcctgg ctgcaatttt gattgtggcc gatctgctcg ttgtatccca ttatgtgatt
    23041 cgaaccggag aagtctggca gttatccgct tttcgagctg aggccatggg tgctcgggag
    23101 caaactgcag ccttttctgc agccattgat gatttgaaga agagactgtc ggccatggga
    23161 gaggtcaatc aacggcttcg ggtcatgctg ggaattgata cgaccaagcc tgctggcgac
    23221 cttgccaatg ggcgaggtgg tgaagatggt cccttgccgg atggaaagag cagtgtacca
    23281 gggaatggac cggcgtcctc aggactggaa tctcggcagc aggtatcgga gctgcgtgag
    23341 aataaccagt ccgacctgga tttctcgacc gagagcattg aagaggcgac ccagcaggtt
    23401 cgtgaaagct tagaagccct cgttcgggaa gccacgcagc aggaagaagc tctccaaagc
    23461 ctgacacagg ttgccgagca gcgctcgacc caatgggcgt ccaccccgtc gatctggccg
    23521 gttcgcggtt gggtcacgtc gggttttggg cccagagtct cgccgttcac tgagaagcca
    23581 gcctggcacg acgggctcga tatcggggcc caggcgaact cccccgtaca ggctccggcc
    23641 cttggtcgtg tggtcaccgt ggcatttgat tccaaaatgg gcaatatggt gaaactggat
    23701 cacgggtatg gcattgaaac cgtgtacggg catcttgcca agtccctggt gaaagagggg
    23761 cagcgcgtga agcgcggcga tgtcgtcgcg ctcgtaggca gcaccggcct ttcgaccggt
    23821 ccacatctcc actacatggt gaagaagaac ggccaggcgc ttgatccgac aaagtttatc
    23881 cttgattaac ttttctgcac cacgtctctg atagtcttcc tgatcgcgtc tcctcacaag
    23941 ctccgtcctt ctctcttcca ccttcccagc tgtgcgaccg cttgtttcct ccactgcgtc
    24001 ccttcaggtt gtgcttcatc aatcaggtaa gacgcgtgct atactgctcg tcctctgacg
    24061 atgttcccct gaggagacat gtatgaccga cttggagatc gcccgttccg tctctcacaa
    24121 acacattttt gaggtcgccc agacattagg gattccttcg gaagacctca tcccttatgg
    24181 ccggtacaaa gccaagatcg ctgccaactt ttctgcgcgc gtgaagagca ggccgctcgg
    24241 gcggtatatc ctcgtgacgg ccattaaccc cactccgctt ggcgaaggta agacgacaac
    24301 ctccgtaggt ttgagcatgg gcctctgccg attgggccat aatgcggcag tgacgttacg
    24361 gcaaccttcc ctcgggccgg tctttggtat caaaggcggc gggaccggtg gagggcgcgc
    24421 ccaggtctgg ccgatggagg atatcaatct gcatttcacc ggggatgcgc atgccgtctc
    24481 tgcaagccat aatctgttgt ccgcattcgt ggataaccat ctgtttcagg gcaatgcgct
    24541 caaactggat ccgcaacgaa tcagatggcc gcgcaccctg ggggtgagtg atcgagcgct
    24601 tcgcgacatc gtattgaatg cggaagcagg gccgcgacca gggcagtttg tcatcaccga
    24661 ggcatcggag atcatggcgg tgttggcatt ggccacggat cagcgtgatc tacgccaacg
    24721 cctcggtaga attctggtcg gcctgacaga gagcggtgcg atgaccaccg ccgaggcatt
    24781 cggttgtgcc ggttcaatgt ccgtattact caaggatgcc ctcttaccga atctggtgca
    24841 gaccttggag ggcacccccg cgtttgttca tgccgggccc ttcggcaaca tcgctcatgg
    24901 gaattgttcc gtcgtctcgg atcagttggc gttgcgatgt gcggactatg tcattaccga
    24961 agccggtttc ggcagtgatt taggtgcgga aaagttcttc aacatcaaat gccgtacatc
    25021 cggtctccgg cccgatgccg gagtggttgt ggcgacgttg cgtgccctca agctgcatgg
    25081 gggaggcggg attgtaaaag caggaacacc gctgccgcca gggttgacgg aagtgaaccc
    25141 ggccgcgctc gaaaaagggt ttgccaatct cgaacagcat attgccaatg tgcgcgcgca
    25201 cggagtgcct gtggtggtgg ccgtgaatgc attcaaagat gattcaccta aggagttgga
    25261 gtgggtctgt gaacgcgcgc tggctgcagg agctgcggcg gccgctgtgt cgactcattg
    25321 ggccgatggt gggaaagggg cggaggaact ggctcgggcc gttgtcaaag tcgctgcaca
    25381 aggatcacag ttcagacctc tttatgatgc cacttggccc atcaagagga agatcgagac
    25441 tattgccacc acgatctacg gtgccgccgc ggtgtcgtac tcgcctcagg cggaaaagga
    25501 tattgaattg gcggcgcgat tggggttcga gcagcttcct atctgtatgg ccaagacgcc
    25561 attgtcgctt tcccacgacc ccgcgcttaa aggacggcca tccgggttta cggtgcccat
    25621 ccaagaattg cgaatcctgt ccggtgctgg ctttctcaca gcggtatgct cgggcattca
    25681 actgatgccg ggcctgccca aaaagccggc gggcgagcgc atcgatatcg atccccagtc
    25741 tggcgagatc gtcgggctgt cgtgatggcg gttagcgctg tttgagaaac cggaagtact
    25801 cagagtctgg actgacgagg atggtggtct tgtctttgag ggttttgcga taggcttcca
    25861 tcgtgcgggt gaactcgaag aaatgggggt cctggcggta cgcgtccgca tagattttga
    25921 acgctttggc atcgccgccg ccacgaagtt cttctgattc gcgataggct tcggcaagga
    25981 taatttcccg gtctttttcg gcttccgact tgatcttctg cgcctcttcc gcgccttccg
    26041 cccgatattg cttggcttgc cgttcccgct ccgcctgcat gcgtgaaaag accgctttct
    26101 cgttttgttc ggggaggtct gctcgtttga tccgcacatc ttgaatctca atgccgtaca
    26161 ccgacgcttt ctcattggcg cgttgagtca cgaccgccat gagttgtgcc cgggcagacg
    26221 acacgatttc tgccaattcg tgccggccca gttcgactcg taattccgaa tagatgatgt
    26281 catgcaggcg ttgcagcgcc ccgcgctggc tctggaacgc ttggtagacc ttcagcggat
    26341 ccgtgattcg ccatttagca aagttgtcga gcaggagagt ctttttgtcc tgcgtgatca
    26401 cgtcctgggc gttggaatca taatccagca gccgcttatc gaaataggta acttcttcaa
    26461 tgaacggcac cttcaggtac agcccgcctt cagtgacatt gcggaccggc ttgccgagct
    26521 ggaccacaat ggcattctgg gtgacatcga caatgtagaa gggggacgcg ccaagaatca
    26581 gcaaaccgat gacgatgccg acaaacgcga ccgcaaatcc ctgcttgctc atggcgtacg
    26641 ctcctgcgtc gcagcggtgg gagccggttt gctgaaacgg tctaacggaa ggtacggcag
    26701 ggctcgctct ccacctttgc catccaggac gaatttgtcg atgtggggca gcacgtcttc
    26761 aagcgtctcg atgtagatgc gcttgctgat gatgtctttc gactggttat attctttgag
    26821 ggtggcgagg aaacgattgg tttcaccctg ggcgcgattc aatctcgcct gcgcgtaccc
    26881 cttggcttga ttcaccaatt gggctgcctc tcccttggct ttgggagtga tgtcgtttcg
    26941 atagccctgc gcctggttga tcagtttttc acgatcttcc ttggcattgg tcacgtcctt
    27001 aaacgccgcg gccacggctt ccgggggatc gacatcctgc aactggacgg cggccacctg
    27061 tacgccggtt ttgtattcat ccagaatgtg ctggagcagc tcctgggtgt catgctggat
    27121 ctgggctttg ccggtggtca gggcttcgtc gattttactc ttcccgatga cctcacgcat
    27181 ggacgcttca gccgccttgc cgatcgtatc gtcgatgtcg gcaacattga acagatactc
    27241 gcgtgaactt ttgatcttat attggacaat gaattcgatg gccagaatgt tcatatcccc
    27301 ggtcagcatc aaggcttcct gcggaatcat ctgctgacgg ccctgccggt cggtacgaaa
    27361 tccaatttcc acgcggtgca atttcgccac tttgggctgc agcacgcttt cgaccaccgg
    27421 aattttcatg tgtggtcccg gttcgaccac tcgaaccgga atgccgaagc gtttgacgac
    27481 cccttcttca tcgggggcca cgatgaacgc gctttgccag atgaggaaga ccgtgaaggc
    27541 gaccaggagg agattgcgaa atccgccggt gggcagcagg ttgcggagtt ggccttgagc
    27601 ctgcttgaag gcctgatcca aatcgtcgcc ctttttgctc caagggtctt tggggtccca
    27661 gaccatcgcg tggctcaatt ctgtaagtgg tggcaacgat gctcgcgggt caccatagca
    27721 aagtgagcac ctgtgagcaa cacctataac ggcgacaaca gccagctgtt ttactcatca
    27781 aaatgtattg atgtagagtg gtggcaagac accgtgatca tgaatccggt ccggacggtg
    27841 gaactgtttc atgcgctggc atggccagac cagacttgaa atttggacga actgaagggt
    27901 ggcgaacggt gcgtctgtga gctgatagat tgccttgagg ccgggcggtc acagctctcg
    27961 ttccattgcg atgttgagtg taagtgtgtc tgatatatca ataagtgtga tgcaaagagg
    28021 agatgccgaa atggatgccc aagcgattcg agagttaatc aaggaaaagt atggtgaagc
    28081 agcggcacgg gcgaaaaccg gaggcagttc ctgctgcggg ctgccccggc gttaatgaat
    28141 gtcgacccga ttacatccaa cctgtattca gatcaggagt gccagggggt accggcagat
    28201 gccgttgcag cgtcgctcgg ttgcgggaat cccacggcac tggcggaact tcaggacggc
    28261 gaaactgtgt tggacctcgg atcaggcggg ggaatcgatg tgttgctctc cgccaaccga
    28321 gtcggaccga aaggcaaggc gtatggactt gatatgactg acgagatgct ggcgttggcc
    28381 agagaaaatc agcgtacggc cggtgtggag aatgtcgagt ttctgaaggg cgaaatcgaa
    28441 aacatcccgc tgcccgacgg gtcggtggat gtgatcatca gcaactgcgt ggtgaatttg
    28501 tccggggaaa aagaacgtgt gttggcggaa gcgtttcgcg ttctgcgacc gggagggcgc
    28561 ttggcgttgt ccgatattgt cgtgcgaggg gcggtaccat cggagatccg aaagaatctg
    28621 gaattgtggg ctggttgcgt ggcgggggcg ctggaagaga cgcagtatgg ggatttgttg
    28681 cggcaggcgg gttttaccga gatcggaatc gaaccgacgc gcatctacca ggccggagac
    28741 gtgaaggagt tgttgatcgg cggagatctc tccagtgacc aacttgtggc tgaagtggac
    28801 ggcaagttca tgagtgcatt catccgggct acgaaaccgg taagtaagag ctagggcgcg
    28861 agcagggacc acaaaggagc agtcgcatag agcttgtgca aacagtcctc gcgccaacgg
    28921 gagacacgaa gcggctgtcg ttttgtgaac aatacttcac tctctggggt tggcagcggt
    28981 ttcctggtgc agaagcccgg ctaagcgaag ttggcaagga gtacgtaggc cagagcggcg
    29041 aaacatccag cggccggcaa agtgatcacc caggccaaca ccatgtcccg cacggttgtc
    29101 cagcggacag cgttgaagcc tttgaggaga ccgatcccga taatggcgga actgctgacg
    29161 tgtgtggtcg acaccggcaa tcctaaccag ccggaacaga ggacgagcgt ggaggtagtg
    29221 aggttcgcag acaatccttc tgcatggtcc atacgcgtga ccttttcggc taacacctcg
    29281 gtgactcgga gcccgcccaa gtagctccct aaacccatgg cgaatgccac gccgccgaag
    29341 gccgcgaact gaaaccagac gctgggccac gtggctgtcg tgctgccgag caggagcatc
    29401 gcgacaattt tgggtgcgtc gttggtgccg cgggcaaagg aggccatccc gctggacagc
    29461 caatggaccg tatcgaggcc caccgtcagg cctcgcagcc ctgcgcggtc acattgcacc
    29521 ggcaccgcca cgaccggctg gccaaacacc gtgctctgaa acaccgttcg tgtgctgccc
    29581 cgtgcgtcaa cggtaaagag tgcccgcgag gccggcatga ggcacaggca ggatccttcc
    29641 cattttgtcg ccgctcgtcg catgacagga tgtaggagga gggagagacc aaaggccaga
    29701 aagggactga gcagcaaggg caacgcgatt tttttgccga tggcggccca caatagtccc
    29761 tcacccgcaa acgccaccag accggttccc acgatggcgc cggtgagcgc atgggttgtc
    29821 gaaacgggca gtcccgttct tgatgccacg agcacccaga gcattgcacc aaacagaatc
    29881 gcgagggcga tggagggtga aagcatggtg ccggtttgca atagaccgtt gctgaaggtc
    29941 ttcaccatcg ctccggcgac cagggtggcg aatccggctc cggccacggt ccaggccgtt
    30001 ccccacatga tcgccgtgcg gtagtttgtg acgccgctgc cgaccagcgt ggcgatggct
    30061 ttcgagacgt cattgctccc attggcatag gccaacgcca acaccagcgc aaaagtcaga
    30121 accgacatat ccatgtgatc tcctgcgcag actgctcaag ccgtcggtcc aacaaggccg
    30181 tagggatgtg agtccgccga ggcataccgg tcaagtatcg tgaaggggaa gaatgactga
    30241 gcgcgaagtt gggcggtacg ttcagcattc ctgattaggt caccgtccca ccgcacgacg
    30301 atcctgcacc ggccgtgcag ccgtaacaat gattgcgagt ggtaatctgc cggtgatgaa
    30361 gtcgggcagg ggcaaagtcc cggatgtgcg caggggcatc gggctgcacc ggaaggtcca
    30421 gcatctggtt gaagtcgcaa tcgtagagca tgccgtccca gccgaccgag agtgtatagc
    30481 ggcacatcac gctgccggcg gcggcgggat tgtacgcatt cgcaagccgt tccatgtacc
    30541 ccagatagtt cccgctctcc accaggaatt cgaggaagcg gctgaccggc atgttggtga
    30601 tggtatagag gtggttgaat tccacgccat gcttggcgcg gagctccttc cggaattgcg
    30661 cttcgatggc ctcctgtttg gctggtagga aggcgccgac cggattgtgc acgagattca
    30721 cgatcaatcc gctgccttcg cgtccgtagc cgaggctatt gaggagctgc agagcttcaa
    30781 tggacttctc gaaaatgcct tcgccgcgtt gcgcatcagt ttgcgccgca cggtaatacg
    30841 gaagtgacgc gacaatctcc acctggtgcg ccgcgagaaa ggtcgccaga tccgcctgcg
    30901 agggcaacag cagcaccgac agattgcagc gatccatgac atggcgattc agggcacggg
    30961 cctgctcgac caaccagcgg aaataggggt tcagttccgg tgcgccacct gtgatgtcga
    31021 cggtaggaat gtcggtcatg gccaaggccg cgatgcactg ctcggctgtc tcccgggaca
    31081 tgcgttccgt tcggtcgggc cccgcgtcta cgtgacaatg gcggcaggtt tgattgcaaa
    31141 gttttcccac gttgatttgg agcaccgtga tgccggtcgc gtggagcggc gacaggccgc
    31201 ttcgccgaag ctggtccgca aatggcaagc aggacccgat ctctgccagt accttcagct
    31261 gctcggcaga ggaagcgagc ggtttatgtt ggccgacgag tgtcagtgcc atggagagtt
    31321 attccaagta ctatggagta tgttcatcgc ctgcattccg gtttcaatgt ttttgctgca
    31381 gcgtgagtaa ggtcgaggtg ggaaatcgca attcgcaaca tccgaagtcc agtacctgct
    31441 cnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    31501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ngtaaggtcg aggtgggaaa
    31561 tcgcaattcg caacatccga agtccagtac ctgctcacca cgatttttta acgcgcgctg
    31621 caccgtcggt tccacacggt aacagacttg tttgccgtgc cgatgtcctt ccaccaatcc
    31681 ggcgtcacgc agaatccgca gatgatggga gacatgcggc tgggaatagc gaagaacgtg
    31741 cgtgagatcg gtcacacatt tttcgcccag gaggagggac tctaatatgc ggagcctggt
    31801 ctcatccccg atggccttca agatcgcggc acactgacgg ggggtcgtga gattggcgac
    31861 gccgtggcgt ggcatcagca gcaagtccct tcaggcgaac aactgaccgc ttcgccgtct
    31921 acgacattcg cgcttcgatg gtagatggtg aaatgaggtc ggtaggcgtc ctgtgtcagg
    31981 acgtgctggg ttttagagca gatttccagc ggcactcccc gatagtattg atgatgatcg
    32041 tcgtcctcgg cggcgatgat gggccctgtg agaatggcat aggcgccctg ccagacgcag
    32101 ggtgtctgct ccggaaggat agcgcaccag cgcgggtcgc ccgccgcgag ggtgatcggg
    32161 gccggaccga tcagaaacag cgagcgcagc ggcgcactcc gcaatagctg tgcagacttc
    32221 gcatcgaggg gctgcggcac gccgcgtcgg tattgctggc ccgattcgtc agtcacggcg
    32281 gaaaacggtc cgcagagggt cgcatacagc ggggcctctt gtgtgaccgc gtcggggagt
    32341 ttgtatccgg tcagggtgac ggagagaaaa tgcacgccgt cgatcgactg ccaagcgccg
    32401 gacttgattt ggtgcacggc gcgaaaccct acatcgacca tcccgccgat gtagtcctgg
    32461 acctgcaagg atccggagag gcagtcaccc cacttggcgg aatcgtggac catgtattgt
    32521 ggaacgactt gatccgacac gatatcggag atcgtgaagc gcccgccggg ttttaggacg
    32581 cggtacatct cgcgaaagac cttgcgcttg tcaggcgcca ggttgatcac gcagttggag
    32641 atgatgaggt cgatgctggc gtcctccacc ggcatcgcat cggccatgcc ctttcgaaac
    32701 tcagtgttcg gtcgggggaa cccgagattg ccggcgacga tgggggcatg ctggcgagca
    32761 atctccagca tggtatcagt catgtcgatg ccaatcacgt gcccggtggg gccgacgcga
    32821 cgcgtggctt cgaagcaatc aattcctcca ccagatccga tatccagcac ggtttcaccg
    32881 gtctgcaccg tgtctaaccc tgccggagtg ccgcacccgt aggaaatttt cagaacggca
    32941 tccggaatga acgagcgcag atcttcaaag ttgtaccctg tcggacagca catctgctcg
    33001 ccggtcgagg cggcccgggc atagcggtcg ctgactttct gggtgatgtc gtctattgcc
    33061 ataaggttcc tttgcgttcg aggcaactat agagatgtct ctatctatca acccttcgta
    33121 tccgaggtca atccggtgaa cgggttggct aaccggtggg acggcgggtt gtaggaatta
    33181 agggggtggc gcgttgtatg tgacgtctga tcgagagatg agcgtaagaa ttgatgcgaa
    33241 tcgcgtaaag agcatgaagc aacacgaacc gtcgccttcg tccccaggcc ctggcaggga
    33301 cagccgaatc gctgcccctg ccagtgtgcg agcgcggcgc gttgcctact gcatcgaggc
    33361 catcggcttt tcgacgatat cccctttcat cgggccgagc gcacccagca actcgttctt
    33421 ttcacgttcc ggcaccttaa acttgttcag cgtcgcgacg agatcgccga ccagcgcatc
    33481 gaaatcgctg ctgctgacgc ccatgcccgc gtgggtgctc ttcatatcgc ggccggtgta
    33541 ggtgcaggga ccgcccgacg cctggcaaat ctgatcgacc agcatggatt tcaggcgggg
    33601 gatgttggcg ttggcgaatt tgccgttgat gcgggcgtcg cctgcgacac gtccgacaaa
    33661 gtcatcgacg acggcggtga tggcggtttt gccgcccaaa cggtcataga gcgatttctc
    33721 cgttgcggca gtcccagccg acggtgagcc catgctgttg caggctgaga ccgttagcgc
    33781 gagaccgaga atcatggcaa gcgacgcaag acgatcagac atgatggttc ctcctggtta
    33841 agatctgtgt ggcgagccgg attcatggtt tccccaaccg gctgctctgt ctgtgattac
    33901 gaaggccgag cgcaattgga tctacggcgc gacaaaaagt gccgttgcgc cccggtggtc
    33961 ccggtgctac agttccgcct gaatcggccg gagactgaac atccaaacga acgggtgcgc
    34021 tcgtagaacg tcacgaggac accccatgtg tgacacccag accgtgg
//
LOCUS       DAOQPD010000038        33754 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_557_length_33754_cov_22.813733, whole genome shotgun sequence.
ACCESSION   DAOQPD010000038 DAOQPD010000000
VERSION     DAOQPD010000038.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 33754)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 33754)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33754
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_557_length_33754_cov_22.813733"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..522)
                     /locus_tag="PK063_10350"
     CDS             complement(<1..522)
                     /locus_tag="PK063_10350"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97495.1"
                     /translation="MAILLIVSLHTNLIARLHLIGGGVGFLVDMPLYLLFWISVPYFF
                     LTAGYFYGRTVDAGAAPFSLLRRSCRSLTLLFVIWVAVYSIIGPNWISNVYTQGLWST
                     ISTEASHTMGRLMQEHVTLLLVPRPPIFHLWFLPALIAGVSTVAMVVTSRLKTWVGAL
                     LVSTYILLVVSAVV"
     gene            1028..1540
                     /locus_tag="PK063_10355"
     CDS             1028..1540
                     /locus_tag="PK063_10355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3015 domain-containing protein"
                     /protein_id="HMZ97496.1"
                     /translation="MKKQGILVLAGLLIGLQSGTAFAVNPDNGPGCGLGKLAWSDYKT
                     PKNIAPQVMMATTNGTFGSQTFGISFGTSGCTNDGKVMASQETNVFVASTFDTLSTDM
                     ARGGGEHLTALATLMNVPVEQQPAFFQLTQQQYLALTEAGEVSSVAVVKALQEAMTGH
                     PTLAQLAGTR"
     gene            1739..2905
                     /locus_tag="PK063_10360"
     CDS             1739..2905
                     /locus_tag="PK063_10360"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HMZ97497.1"
                     /translation="MTQPSHRLLLLTIIILGIGLYTLDLYLPLGIGNGVLYGGLVVMS
                     LAIPDRKIPLLVAGTCSVFALSDVFLGVTLPNVPLWMGLSNRMFSLTAIWFPVVYAFQ
                     RRKSEEALRNAHNELEIRVEARTRELALVNQALVGEIEERMETERSLRASESSLKVSQ
                     EELRQSREELRALAGQLLTAQEVERRRIARDLHDDVNQRLAMLAMDLRRIEKGEAGDL
                     SNIGGMVKSISGRLTAVSDDVRQMAYRFHPSILDDLGLMKAVRRLVDDFSASTGIEAV
                     YVYQDCLSPVPTDLATCVYRIAQESLNNVARHAKATEVEVELICDEGMITLSVRDNGV
                     GFDAVHASQGRGRLGLLSMKERVRLVRGTLNVSSSPGGGTHIEVGVPLSGSQHV"
     gene            2898..3542
                     /locus_tag="PK063_10365"
     CDS             2898..3542
                     /locus_tag="PK063_10365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ97498.1"
                     /translation="MSKPRVLLADDHSLVLEGFRRILADQCELIGMVEDGRALLEAAA
                     RLEPDIVILDVSMPLLNGIDAATQLKKTHPSMKVIFVTMHSDADYVRSAFEAGASGYL
                     LKRSAVDELEQAIRAVWAGHSYITPLIAKDLLDVLLTAGPGQTPQKKTLTFRQREVLQ
                     LLAEGRTVKDIALRLKISTRTVEFHKAQVMEQLNLRTTAELIKYALTHGLLAPS"
     gene            3787..4431
                     /locus_tag="PK063_10370"
     CDS             3787..4431
                     /locus_tag="PK063_10370"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024831.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HMZ97499.1"
                     /translation="MRIAQISQCFEEVSNESERPEVRGVEFVTRSLMRFGHDVTVFAS
                     GDSRVSGRLIPVSPQAIRHYPSPKRHLSEGLTFLAIEKAFSMESSFDLLHVHAGFVAF
                     PMMRRSPLPSVATVYGSLDAPEILQLFRAFRELPLVATSAEQIRQCPELNWLALIPVP
                     GPRQRSEVPAETMDSLVETATAYTAVYESIVERAVRPTHAVRPAYSLYDVQTTV"
     gene            5120..6235
                     /locus_tag="PK063_10375"
     CDS             5120..6235
                     /locus_tag="PK063_10375"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97500.1"
                     /translation="MPTGLPPGLLRVIDQIVCVAGTSGRGTDLWDGIRVECEREYSGI
                     RHGKGTLAHALEWEILKLQTRLESSAYGNPVVPVPLFRNRHVHIGSLIRLWRRLALET
                     EEWLASQGYDTLLDVGPWGGFNFVLEPDGYTRMPFARLTLAVGGLPSTPFHEQGGPLF
                     QHLLPRYHAELQQAGVNFPPLWQYHHAKHDASVRLREVSATHYLPTHSYERRTFVKVR
                     VSRDCEAVEEIALQDFLLLLERLQFTTDWELYREQTKDVDARFDLQDFISLNHMVEGV
                     YQRTDAEDRLLHEMKDAFRGAIRARQVLYGYLSQVVKLRWVENLYWALAEAALGVKRY
                     QRMVSFDREVCPQIPPRLLIPVRRHLNRYHNRVGGTA"
     gene            complement(6255..7226)
                     /locus_tag="PK063_10380"
     CDS             complement(6255..7226)
                     /locus_tag="PK063_10380"
                     /inference="COORDINATES: protein motif:HMM:NF013087.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HMZ97501.1"
                     /translation="MTYQQLMSLANGYAESKTLLVANELGVFTAIGTGGRSAEELAVS
                     CGTVREGMKLLLQSLTGLGLLHLKAGRYWNTPLGRTFLDGGSPLAITNLLWLLNHHWV
                     DWSGMTKAIRRGPPGWAPVTKTANFRRRFALAMQERSHILVQPTIDSFRLPRQAERFL
                     DLGGGAGSYAIALARRYPTLQGLVIDQSVTVAKRLIRRERLANRIQVQEGDLRTLPLP
                     TDLDVVLLANVLHDFNKTENRHLLRRTRKALRPGGRLFIVEYFLAREETRPAEAAVFS
                     LLMFAFTGTGRCYSWNEVEAWLRQAGFGRCRRHKVTGSIGTLEATKL"
     gene            7403..8155
                     /locus_tag="PK063_10385"
     CDS             7403..8155
                     /locus_tag="PK063_10385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HMZ97502.1"
                     /translation="MLDVIGLGAVAGLIPVYLGIFAALYLGKVLPRTWEGGLIGVANG
                     VLVYLFFDLMHEATEQTGARDPLSWLVFLGSLGVSFVGLVALESSQVFGARSGNRILS
                     LPYMIAVGMGLHNLGEGLAIGASYAGGEYTLSALLVAGFGLHNGTEGFGIVGAAGKTP
                     ISWRDVALLGLIAGLPTCVGTFLSGQGVSSYFSICFYALAAGSLLYVVLSLTVMSYTA
                     TRRVQVSAGMFTGIAIMYLTAMILTLVSGVRS"
     gene            8371..>8642
                     /locus_tag="PK063_10390"
     CDS             8371..>8642
                     /locus_tag="PK063_10390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008612 - peptidyl-lysine modification to
                     peptidyl-hypusine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyhypusine synthase family protein"
                     /protein_id="HMZ97503.1"
                     /translation="MAGREFHDGAKDGLEALEPLDPEKIHSFTELLEAMRKTAFGGRR
                     LGEAYETLAAMIEDPDCKVVLTLSGAMTIAKMGKIISTMIDRGMVQA"
     assembly_gap    8643..8742
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <8743..9629
                     /locus_tag="PK063_10395"
     CDS             <8743..9629
                     /locus_tag="PK063_10395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008612 - peptidyl-lysine modification to
                     peptidyl-hypusine [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="deoxyhypusine synthase family protein"
                     /protein_id="HMZ97504.1"
                     /translation="AKMGKIISTMIDRGMVQAIVSTGALVAHGLSESVGKLHYRHEPS
                     QTDEELFQKGYNRVYDTLEMESNLNYVEHVVSQTMKRLNVDQPLSSNFLTRELGKTLA
                     EEFEGPGILKSAYLKNVPVYIPAFTDSEMGLDLGTWAMGKQIDFTRSQIKEGGDVAVL
                     RALHQTCPVFNPYLDLNHYAEEVLGSTRLGIFTIGGGVPRNWAQQVAPYIEISNTRLG
                     LNVEPPRFHYGVRICPEPDYWGGLSGCTYQEGISWGKFVPPAEGGRFAEVLSDATLVW
                     PLLMVGLLERFAAKSVSA"
     gene            9626..10279
                     /locus_tag="PK063_10400"
     CDS             9626..10279
                     /locus_tag="PK063_10400"
                     /inference="COORDINATES: protein motif:HMM:NF024853.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HMZ97505.1"
                     /translation="MTPLTGWMIRFATPFLLLVLTTASALAASSPAVDNRMRGKADAP
                     ITLIEYSDFTCGYCLKFFKETWPKIHARYVETGKVRFLYKDYPRADQGPGVTAALAAR
                     CAGDQGTYWPMHDRLFAADGRLDVDSYFQHAKAIGLDQSKFRECLRDAPHMKAIFQDR
                     DEANAWGFHGTPGFILMRTTQQPTAQNPALAIPGAFPFAAFEEEIEKLLAASGEKAK"
     gene            10359..10637
                     /locus_tag="PK063_10405"
     CDS             10359..10637
                     /locus_tag="PK063_10405"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97506.1"
                     /translation="MGSKQAFWTVPAKDGEPDLWVCMSCLSEAFCRKVPMPACPTCHG
                     VSTYEAFTLAAVQDWGTEELIAKAVAAQQEEAALSAAASAAPPVESVQ"
     gene            10665..12095
                     /locus_tag="PK063_10410"
     CDS             10665..12095
                     /locus_tag="PK063_10410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HMZ97507.1"
                     /translation="MENGRPFLIGGRWSQSTTVAPVRNPYTGETIAHVCQASPADVES
                     AIQSSVDGAAAMRRLSGYARSTLLANAAQALQARQEEFARTMTAEAGKPLTDARREVG
                     RAIQTLSIAGEEAKRIGGEVVPLDWSPGMESYWGVTRRFPIGPILGITPFNFPLNLVV
                     HKVAPALAAGNSILIKPAPQTPLTALLLGDLLLKAGVPPGGLNILPCDNTLAEQLVVD
                     PRFKLLSFTGSAPVGWMLKAKCGKKKVVLELGGNAAVIIEPDADLEYAAQRCVTGGFT
                     YAGQTCISVQRIFVHESIAESFTEQLVARVRALATGDPGDERTVVGPLIDAGAAQRIE
                     GWIDEAITQGARLLSGGSREGSVVRPTVLSQVTAGMNVSCREVFGPLVTITPYREFEA
                     ALRAVNESDYGLQAGIFTTNIGRIFQAFEQLEVGGVLANEIPTFRADHMPYGGIKDSG
                     IGREGLRYAIEDMTEPKLLVVNLRRP"
     gene            12271..12846
                     /locus_tag="PK063_10415"
     CDS             12271..12846
                     /locus_tag="PK063_10415"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: protein motif:HMM:NF013979.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008792 - arginine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006596 - polyamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine decarboxylase, pyruvoyl-dependent"
                     /protein_id="HMZ97508.1"
                     /translation="MVPTHMFLTRGVGVHKEKLAAFEQALRSAGVAYCNLVSVSSILP
                     PNCKILPRKRGEKLLNPGEITFCVMARSETNERNRLISASIGLAIPTDRDTYGYLSEH
                     HAYGETDEESGEYTEDLAAQMLATTQGIEFDPDVAWKEREQVFKMGGKIVRTLNITQS
                     AVGRPNRWTCVIALAVFIPTENIPKSLRNKA"
     gene            12855..13787
                     /gene="speB"
                     /locus_tag="PK063_10420"
     CDS             12855..13787
                     /gene="speB"
                     /locus_tag="PK063_10420"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: protein motif:HMM:TIGR01230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008783 - agmatinase activity [Evidence
                     IEA];
                     GO_process: GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HMZ97509.1"
                     /translation="MALPSGWLGQADNFLGIDEPWCHPDQAGVYVLPAPYEHTSSYIL
                     GSDRGPSAIIEASQQVELYDETLRYEPYREWGGVATANTLNLNGRVDGQAVQAIQDFV
                     QPHVGRGKFLVTLTGEHTGALGAIRAHAQHYSGMCVVQIDAHGDLRQAYQDNPYSHAS
                     VMARVVQDGLPLVQVGIRSISPEEIELIDKTPRIKTFFAASILDPSGPYEGRAARWIP
                     EVLASCPGPVYLTFDCDGLDASLVPALGTPEPGGLGWYDTLALVTALANGPGIVGMDI
                     SEIAPIEGFVAPQFSIARLIYRMLGRVRAGRRVH"
     gene            13884..14594
                     /locus_tag="PK063_10425"
     CDS             13884..14594
                     /locus_tag="PK063_10425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HMZ97510.1"
                     /translation="MRINKFFTEQGLCSRREADRLVAEGRVTINGVVAKLGDQVSSQD
                     VVARDGTILQRGNRAVYLKYHKPVGVTTTTELHVTRNIISEINHRERIFPIGRLDKDS
                     SGLILLTNDGDIVNEILRVEHGHEREYRVEVDREFDDAFLSRMAEGVVILGERTRPCL
                     MARVGPRRFRIILTEGRNRQIRRMCQALGYRVVSLHRVRIMHITVEGLHAGQWMDLSE
                     EERRRLFQALGRPPESSL"
     gene            complement(14608..15384)
                     /locus_tag="PK063_10430"
     CDS             complement(14608..15384)
                     /locus_tag="PK063_10430"
                     /inference="COORDINATES: protein motif:HMM:NF024140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MCP four helix bundle domain-containing protein"
                     /protein_id="HMZ97511.1"
                     /translation="MSFASRFKLSFPSTNQLIISLLIAGLGWISGQALSRIDQDLRIM
                     YTEYTLGAADLAHISADVIRYRNTIIRSLEAENQAVFERITESLPAQRARIQHAVDRY
                     AAAGLRVSRSGRSEEKDIQAVRESLDQYFHVASKTVDLLSQEWKAGTPGEATELRRKA
                     EIHAADNGGPKVMQVSLALDRLLETVAEVAKDMRDEGTKTIRSTSYWIVGGSFFIALL
                     NLFLSRTTRAPLSASRPEESVRPDSLDLPGGGSNTALRAE"
     gene            complement(15500..17176)
                     /locus_tag="PK063_10435"
     CDS             complement(15500..17176)
                     /locus_tag="PK063_10435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ97512.1"
                     /translation="MNPIATESTITTPSAWTILSRLNLLVELERRILAIIASYAVVIG
                     LFALIVPLTVQELVNTFAFAIQPIMIVTLVAIMLGALLLMGAFRVLQGRAVEILVQRI
                     YTRLAVAFTEALPRFRENVFLPQHTNTFIEAELLPRALVAMLVDIINVFVSGMIGMTI
                     LIMYHPYFLGYNIFLITGFAFLLTFFGRGGLRITQRVSNLHYQTFHWLQDIGINRLHF
                     KSTDSLPLLLKKTDALVQAYVMARKTRSDILTGAQYKSTVIFQAIAHSSMIGLGGWLL
                     SLADITLGQFVAAEVIVGTLLLNLDIVARRMYAAIYVATSMQELSRLFEMPKEEVSGP
                     IAAWLPNPTLQGVRLTCKDVSFASPEGPMLFDHFNLEVLPGEKISVLTGTSKSKTSLA
                     LLLAGLYHPTSGVIRYNDIDLRDVSLNYVNRCRGLMLDSHPTLFDGTLEENVTLQRPS
                     IQFADLSWALRFVELEEEIDALPLGLETVVHGNGANLSRSQVLRILLARMIVTRPELL
                     IFNGSLHNIDPTVRLTLLRRLCAKEEPWSIVFVSNDPEVGQLVERRVILD"
     gene            complement(17319..18986)
                     /locus_tag="PK063_10440"
     CDS             complement(17319..18986)
                     /locus_tag="PK063_10440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HMZ97513.1"
                     /translation="MSQDHSDNQSNLFQAVVGHLGLLFRLERRILGLIVSYSIAIGLF
                     SLIVPLTVQELVNTFAFALQPITIVTLAAVMVAGLLFVGAFRALQYYAVEVLERRIFA
                     RVAIAMAQQLPHLRYQGFKPRFANYFVETILMQRAVSVLLVDLINVIVGGAVGMTILV
                     FYHPYFLLFNAILLVGFNVVFFLMSHGGLKADMDMSHAKYDTLHWFQEIAYNLLHFKS
                     TDSQALLIKKTDQLLDNYVGVRRTRFGILIRQYLGSLGWQAIVHSGLIATAGWLLGIG
                     QLTLGQFVAAEVVVSGILSSFDGVVKRMGHIYYFLTALTELSFLFSLPKDQDAATLSI
                     PLPDPTVHGIRVTCKDLTFAPAGGPPVFEHFNLEVTPGEKIGIYADTTMAKTALARVL
                     GGLESPTAGVIRYNGVDLRHLNLDSVNRFRGFILDSQLSLFEGTLEENILLGRDYIPY
                     SDVRWALRFTELEEEVDALPHGLKTHVRSAGKIFAPTHIVRILVARAILGRPQLLIFE
                     GILHNMHPAMRETILRRLCSKEEPWSVIFVSNDPNLTPHVDRRIMLN"
     gene            complement(19119..20609)
                     /locus_tag="PK063_10445"
     CDS             complement(19119..20609)
                     /locus_tag="PK063_10445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HMZ97514.1"
                     /translation="MKNYAWILVIAACALWGLPESSAQAEDTGKAKTLPPIPLSLNEV
                     HAWIDRSHPLLKGAGTEKTSARGKMLKALGAFEPVLVNDTEIERFIDKSTSKTQSVGF
                     NDTLVEARTPWGFRGSAGVRQAIGDAKIPDLSFGNGNQQVILGGFLPLLKGLMINPEN
                     AELQRSELADPRAEVKISQTRQDLFLAAASQFWDWVSAAKFVDVQRRALGVAEERLRQ
                     VEGRAKAGAVAPLDVVEAGQEVQRRREISIAAQRAVEQEQYKMSMFLWENQTPTTPQL
                     ERVPDFPPPAAAPTADIIKADKLQAKNDRPEIREVDIEAKVNNIDLELAKNNLLPSLD
                     LEAAPARAPEKFVLGLGYRFGAELRIPILQRRSRGEVMEAQAQADRLVLVQKYREQQV
                     VVDVDNAVSAIERAKERVAAAAESLRMAKTLEEGERFRFSLGATSVLFVNLRERNSVD
                     SEMQLVRAKADYQKALALYQWATGSWARSQPSAVPVNYRVGASLSK"
     gene            complement(20698..22134)
                     /locus_tag="PK063_10450"
     CDS             complement(20698..22134)
                     /locus_tag="PK063_10450"
                     /inference="COORDINATES: protein motif:HMM:NF024923.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoyl-binding protein"
                     /protein_id="HMZ97515.1"
                     /translation="MQRIREGLKTRFRSLVTQRTGLDEMAVDDLATSTKLQSWEAVQI
                     PERLRFSSRLAILLVGFFMLIVAFVPWTQTITVTGQLSAYTPFERPQDIEAQITGRIR
                     KWHIFEGVRVKAGDVILELDDYDPNFMAPDLLNLLEQRKQALEDTRKAALSRADQLDK
                     RIKEMQNLVKAAVPSAGARVLEAESKVREARQKIEASKIAVATAELNVERHQQLAQQG
                     LVSQRELELTIQAAIASKADLQGAQANLAAAEQGMKALSFGREQVSAEVLQRLLDAEA
                     ARDASIGEAARAADQVADVSLRLSNANQRRVASRILSPIDGTVVKMAQAGAGETVRPG
                     EKLVRISPNSVDRAIEMVADGIDAPLLNVGRKVKILFYGIPAIPLPAWPEMMAGTYNG
                     VIKVIDQVDDGKGNFRFWVVPDLEERPWPPQEHVRQGTKAMGWVILNRVPLWYELWRR
                     FNLFPPDYQERPPSLIDTLLPKAGRGAK"
     gene            22308..22862
                     /gene="purE"
                     /locus_tag="PK063_10455"
     CDS             22308..22862
                     /gene="purE"
                     /locus_tag="PK063_10455"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HMZ97516.1"
                     /translation="MPKKKRADRALVGVLGGSTSDFPILEKAVAMLNELGIPNELLVV
                     SAHRTPDRLFAYAEQAVARGIQVIIAGAGGAAHLPGMVAAKTLLPVIGVPIPTEHLRG
                     FDSLLSIVQMPRGIPVATVAIGGAENAAILAAQILGVQSASVRQRLERFRAAQTQKVL
                     DSQDDARLSPPFPMSRGTRTSRRP"
     gene            22859..24025
                     /locus_tag="PK063_10460"
     CDS             22859..24025
                     /locus_tag="PK063_10460"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: protein motif:HMM:NF004679.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HMZ97517.1"
                     /translation="MNVTVIDPGATLGVLGGGQLGAMFATAARRMGYAVNVWDPDPEA
                     PAHRIADHSLIRPFTDADARKEFTQRVRAVTYEWENVPADLCEQLECELPVRPSSRVL
                     RVIQDRIEQKTFLRSRGLPVPVFATLASPEELGRQTMPAYPLVCKTATAGYDGKGQWK
                     ILRAEDCPAVQQELARTRRPGSRWILEEWLPFQRELSILVVRGADGASQTYPLVDNVH
                     EEGILRQTIVPADVPQPVADLAGTIACDAVQALDGVGVFCVELFLMADGRLVINEIAP
                     RPHNSGHYTLDACTVSQFEQQVRTLCGLPLGEIRLLSPAVMLNLIGEDVRLVTHSPAA
                     QDLLRVPGAIVHLYGKRTIRPKRKMGHISFLAPTRAEALTAASTFRSRFAPIHS"
     gene            24280..26139
                     /locus_tag="PK063_10465"
     CDS             24280..26139
                     /locus_tag="PK063_10465"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ97518.1"
                     /translation="MSVPLSSDLDQTGRHPTMRGLGRLFSHSRVRVMFLQSLVAGILS
                     YELLVSNETIYGQNVSRMVALGLMLISMGIILLPKAALESTWFPGALISINTLLVTGT
                     IYLSGNASSELYLTYFLLLLIASSAPSLKQLLGLSVIICAGYGILVYEHAMQSGTLAV
                     GHLLGIPVLLIMSVFYGLTLETVAVERRRNRLLREDVQGLKQSEQVLEERRTQLETRV
                     QGLKQGLSRANQEIRQGMVERTGLERQLREAQKFEAMGRLASRLAHEFNQVLAVIGAQ
                     TGAIVSKLKPDDPLHGPVEDIFRSGERAATLTAQLLALGVHETSIRDTLSLGEAIVSM
                     REALQALLPGRIDVRVPDESKPVLVEIGHDRLECLLLHLVANARDAMPSSGRVDISLE
                     VVTGELLPAEQLEKNPRKRMARIAVSDSGGGMNLDVQAQMFEPFFSTKETHAGLGLTL
                     VYGIVRQCGGTVEVQSQPGQGTTVRVYLPLVERNAVLRDSRVLPEALSKGAETVLLVE
                     EDEIARKLALSTLHGHRYHVLEAGSAVEALLVAQQYQGPIHLTVSHLSMPEISGRELA
                     KRLVLQHPKMKALFVSGFSDETIASHRVNRKYFLQQPYRQHDLAGKVRELLDV"
     gene            complement(26156..26860)
                     /locus_tag="PK063_10470"
     CDS             complement(26156..26860)
                     /locus_tag="PK063_10470"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HMZ97519.1"
                     /translation="MLPLSDDNPTERTPVVTVAFIVACSLVFLYQSSLGSTSGEAFVY
                     QYGAIPSLVFGQAVLPPELTRIPAYATVLTSMFLHGSWMHLIGNMLYLWVFGNNIEDI
                     MGHVRFIVFYVGCGILAALSHALTDPTSTVPMVGASGAISGVLGAYLLLFPHARVLLI
                     APVVGATYVPAGIVLGLWFVMQLLNGGASLGSQGGGVAFFAHIGGFIAGMVLIGFFKR
                     PEVRFFKPGRTESFRY"
     gene            complement(26883..27740)
                     /locus_tag="PK063_10475"
     CDS             complement(26883..27740)
                     /locus_tag="PK063_10475"
                     /inference="COORDINATES: protein motif:HMM:NF014342.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DHHA1 domain-containing protein"
                     /protein_id="HMZ97520.1"
                     /translation="MSAATMRTLSSSPPTLILYHAECADGFGAAWAIWRRYPDAEYRP
                     VKHGEAPPTNLAGHHIVMVDFSYNRSTLEAMAKDAASLVVLDHHITAEQALADLPYAY
                     FDLNKSGAVLGWEWAHDEPAPWLLRYIQDKDLWHWALPNSREISAALASHPFDFELWT
                     RFEQRELEREGRAILRYENELVTKLASHATLVEFEGATVPSVQSSVLTSQIGERLSAE
                     HPFCVIWHDRNGRRYFSMRSREEGTDVGAIAASFGGGGHTHAAGFSVPLQADGLPQAN
                     PRLPRPAAS"
     gene            complement(27835..28890)
                     /locus_tag="PK063_10480"
     CDS             complement(27835..28890)
                     /locus_tag="PK063_10480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HMZ97521.1"
                     /translation="MKTPAARSKPVPTKDEILTQITTLLDRPDDDVQAALMKEILAGV
                     IRLSESQLDVLDLKIVNRALKELRHAFRVFQGYRDRLKISVFGSARTPADDPNYQLAF
                     QFARRMVEEGYMTITGGADGIMRASQEGAGREHSFGVNIMLPFEQGANAVIADDPKLV
                     TFKYFFTRKLMFQKESHAIALFPGGFGTHDEGFEIMTLVQTGKSDPKPIVCLQAPGCD
                     YWNHWNSFITDQLLKRRLINAEDLSLFTIVDNVEDAVTEIRTFYRRYHSLRFVGRQLA
                     IRLKTPLTAEQVQEVQHQFKDMLTEGTFEQRPSLPEEIDEPGLKDLARLTFSFNRRNA
                     GRLRQLINHLNHLPATT"
     gene            complement(28992..29702)
                     /locus_tag="PK063_10485"
     CDS             complement(28992..29702)
                     /locus_tag="PK063_10485"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HMZ97522.1"
                     /translation="MMTPGVVQIPGDVSVSEAASLLDREQMPCLLVKDGEAAFGIMTS
                     GDIVKKVVAQGLEPHDVEVRSIMSKPVHSVECDQILDDATSVMASTGTSLLIVTKQGQ
                     PVGILTARDLALAPKRCETCLPATIRVTNGEGEGAKHTATIRQLSHVGASIESRTLLL
                     PGTSIVLSFILPGTDLSFSLQGTILNSNYEPEFHEDRNVLGTYSGIDIQFLSLSSSDE
                     SKIRAWVLQNLPRASDLS"
     gene            29963..31441
                     /locus_tag="PK063_10490"
     CDS             29963..31441
                     /locus_tag="PK063_10490"
                     /inference="COORDINATES: protein motif:HMM:NF016970.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF692 family protein"
                     /protein_id="HMZ97523.1"
                     /translation="MKSEFTERAHRLPAHGLGLSVDVYSPDLLELVRALRDAALEPDY
                     LEIFKATTSAQQWMRQQLPDLKLTYHGEGLWSTQPEFCRSGSGRQGVAEACAQLAALR
                     SAWLNHECATKQMAGYAFGTYLPPLYTELSARMTAENVAYLQSQVDQDAHRREIDPAL
                     VLLEMPPLTYFGCGALPIPDFFRAVTDQASCGLVLDIGHLWTVYRYTGSWQRQRLEEF
                     AAQFLDAFPMERVIEIHVAGLAELTVPHPSGIDASGNALPYWIDAHGAPIPGVLFDLL
                     AQVLSHPGLTSLKGVALEVDTKPIAMIVEEFKQFRERFGTTVQAMLHRDSPAPVQPQR
                     SPNARSAERRQLTSEEEATLQQQYLHYVQLVTTQDDPSSIRNLSLLGGSLDDLNRYRE
                     TYLPHELLHWGGELQDMFPDTCRALTESDVPLDRFVAVWFSKPRPEQDDYDFFLLKID
                     RFVEFATHACPMAAMIVMREAEELRAAYRQANEPIGSSQVRA"
     gene            31438..32622
                     /locus_tag="PK063_10495"
     CDS             31438..32622
                     /locus_tag="PK063_10495"
                     /inference="COORDINATES: protein motif:HMM:NF013380.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HMZ97524.1"
                     /translation="MNFWTTLPQPILGLAPMDGVTDAAFRRVVASQGRPDITFTEFTN
                     VNEICRGPDHLLSSLIYSEAERPIVAQLYGKDPEQFYRAAQVVCELGFDGLDINMGCP
                     SKSVAASGSGAALIKTPDLAHAILRAARQGLEDWAGGQSIHQQGFKPSRIEFIHELNH
                     RRSGSPVVPRRLLPLSIKTRLGFDCVVVERWVEHLLEVRPAAITVHGRTLQQMYRGAA
                     DWTAIAEAARVARDTETLILGNGDLNTLVDAVRRAADSRVQGVLVGRGTLGAPWFFRE
                     KEQARRAFVEQVDLSTLPATMWEPPVSLRHRMQVMLDHARQYEAIAGLECFRSIRKHL
                     GWYCKAFPHAAAMRGKMFGVSNVQDVERIVAEFCQDLILEEAAGSDAAPIAPQFPYPC
                     AS"
     gene            32627..33259
                     /locus_tag="PK063_10500"
     CDS             32627..33259
                     /locus_tag="PK063_10500"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: protein motif:HMM:TIGR00172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maf family protein"
                     /protein_id="HMZ97525.1"
                     /translation="MRLILASTSPRRHELLTLLGVPFDVVAPPFIEQVQPHLSADSQA
                     VEFAAGKARSCVSSCPDALILGSDTLINLGSEVLGKPLDLAGAEVMLRRLAGQTHRIV
                     TAVALAGPEPERCDVRLAEVLVTMKPLNEATLANYLRTGDSLGKAGAYSIQGGGAAFI
                     ERIEGDFTAAVGLPLQLVAEMLRQRGLSCPVDIDQLYASRPYPNWDRFRP"
     gene            33438..>33754
                     /locus_tag="PK063_10505"
     CDS             33438..>33754
                     /locus_tag="PK063_10505"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97526.1"
                     /translation="MALAISGPAWAIDVKLSPEDAKKALEAGRAPMEKAASPEDVKKI
                     LQQASLVTRVGADPEKDPCGASAILRTKRYRLEAFGRQEAAESKKQKKDVRMPDEFIQ
                     KVV"
BASE COUNT         6768 a         9341 c        10390 g         7155 t
ORIGIN      
        1 aacgactgca ctcacgacga gcaggatata ggtcgagaca agcagagccc ccacccatgt
       61 tttgagacgg ctggtcacga ccattgcgac cgtactcacc ccagcgatca gcgccggcaa
      121 gaaccagagg tgaaagatcg gaggtctcgg cacgagaagt agtgtgacat gctcctgcat
      181 gagcctgccc atggtatggg aggcctccgt cgaaatggtc gaccagagcc cttgtgtgta
      241 gacgttgctg atccagttcg gtccgatgat cgagtacaca gcgacccata tgacaaagag
      301 gagcgtcagc gagcgacacg agcgccgtag tagggagaag ggggctgctc cggcatccac
      361 ggtgcgcccg taaaagtatc ccgccgtcaa aaagaaatag gggacggaga tccagaacaa
      421 tagatagagc ggcatgtcca cgaggaagcc aaccccgccg ccgatgagat gcagacgtgc
      481 aatcaggttt gtatggaggg atacgataag caggatcgcc acaacgcggt agctttcgat
      541 gctggcgatg cgaggaggcc gggcatgtgg cgggatcggt gcagtgcttg gcatgaagcg
      601 atagtcggaa cgatatttct gcccggtatt cgatgcaaga caaacgcctg tccttgagca
      661 ttcctgtcgc acgcacgatg caccgacaga accggtgaaa tcccgccatc catgaagcgt
      721 cgctctagcg agcgcctcac agatagcagc tcagatccaa ttcaacggaa taaggagtct
      781 ggtccgcact gagcgattcc gcaccagccg cacgatacga aacgcgttgt tcgcctttct
      841 tgtcagtgaa agtctcacgc agatacttga gcgatcagca cccccgccgg tttcttcttc
      901 ctgcacgaaa aaaccggcgc ttcaattgac agggtgaaaa agacagctaa ggtagaaatc
      961 gcgcagagaa agcggctaac cgtttttgcc cgtagcacag acatcgaaga acagaagggg
     1021 ggagctcatg aagaaacaag gaatcctcgt gcttgcaggt ctgttgattg gtcttcaatc
     1081 cggcacagcc ttcgcggtga atccagacaa cgggcctgga tgcggattgg ggaagttggc
     1141 ttggtctgat tacaagacgc cgaaaaatat tgcgccccaa gtcatgatgg cgacgaccaa
     1201 cgggacgttc ggcagccaaa cgttcggcat cagttttggc acctcgggtt gcaccaatga
     1261 cggaaaagtg atggcatcgc aggagacgaa tgtctttgtc gccagcacct tcgacacgct
     1321 gtcgaccgac atggcgaggg gtggtggaga acacctgacc gcactcgcaa ccttgatgaa
     1381 cgtgccggtc gaacagcagc cggccttttt tcaattgacg cagcagcagt atctcgcgct
     1441 gaccgaggct ggagaggtgt cttcagtggc ggtcgtgaag gcgttgcagg aggcgatgac
     1501 cggacatccg accctggccc agctcgccgg cacacgttaa tcggttcgct ccttccgctt
     1561 ttcggaaacg gtagtgaacg gtcgggggcg gtgactttct gtgccgccct cgccggtcgt
     1621 tctgcctacg gtactcatct atcgccgttg agctgcccct gagcgagagc gaattccctc
     1681 catctgattg tgtctttgct tgaagccttc cggctgaggg gaggataatc gctcatccat
     1741 gactcagcct tcccaccgac tgcttctgct cacgattatc atcctgggga ttggtctcta
     1801 tacccttgat ctctatctcc cgttgggaat cggaaacggg gtgctctatg gcggccttgt
     1861 ggtcatgtcg ctggcaattc ccgatcgcaa gattccgcta ctggtggccg gcacctgttc
     1921 ggtcttcgcc ctgtcggatg tgtttctcgg tgtcacgctt cccaacgtgc cgctctggat
     1981 gggactgagt aatcgcatgt tcagcctcac ggcgatctgg tttccggtcg tctatgcctt
     2041 tcaacggcga aagagtgaag aggcgctccg caacgcgcac aatgaactgg aaatacgagt
     2101 ggaagcgcgt acgcgggagc tggcactggt caatcaagcg ctcgtggggg aaatcgagga
     2161 gcgaatggaa acagagcggt ctcttcgtgc cagcgaatct tccttgaagg tgagtcagga
     2221 ggagctgcga caaagccgtg aagaactgcg ggcgttggcg gggcaattgc tgacggcgca
     2281 agaggtcgaa cggcgccgca ttgcgcgtga cttgcatgat gatgtcaacc agcgcctggc
     2341 catgttagcg atggatctca ggcggatcga aaagggtgaa gcgggggatc tttcgaatat
     2401 cggtgggatg gtaaaatcca tcagcggtcg gttgactgcc gtgtcggatg atgttcggca
     2461 gatggcgtac cggtttcatc cctccatttt agacgatctg ggccttatga aagcggttcg
     2521 gcgattggtc gatgattttt ctgccagcac gggaatcgaa gcggtgtatg tctaccagga
     2581 ttgtttgagt cccgtgccaa ccgatctggc cacgtgcgtg tatcggattg ctcaggagag
     2641 cctgaacaat gtggcccgac atgctaaggc gaccgaggtc gaagtggaat tgatttgtga
     2701 cgaggggatg attactcttt cggtccggga caacggagtc gggtttgatg ccgtgcatgc
     2761 gtcgcaggga cgggggcgcc tgggattgtt gagcatgaag gagcgcgtgc ggctcgtgcg
     2821 aggaaccttg aatgtctcgt cgtcgccggg gggcgggacg catattgaag ttggcgtgcc
     2881 gctgtcaggg agtcagcatg tctaaaccgc gcgtcttgct cgccgatgat cattcgctgg
     2941 tactcgaagg atttcgccgc attctcgccg accagtgtga actgatcggg atggtcgagg
     3001 acggccgcgc actgcttgag gcggcggctc ggctcgagcc cgacattgtc attctcgatg
     3061 tgtccatgcc cctcttaaac ggcatcgacg cggccacgca gctcaagaaa acgcatccgt
     3121 cgatgaaggt gatttttgtc acgatgcatt cggacgccga ctatgttcga tccgcctttg
     3181 aggcgggggc gtcggggtat ctcctgaagc ggtcggcggt cgatgaattg gagcaggcca
     3241 ttcgggctgt gtgggccgga catagctaca tcacgccgtt gattgcgaaa gatctcctcg
     3301 atgtgttgct caccgcaggt ccgggacaga cgccacagaa aaaaacgctc acctttcgcc
     3361 agcgtgaggt gctccagtta ttggcggaag ggcgaacggt gaaagacatc gcgctccgcc
     3421 tcaagatttc cacgcgcacg gtcgagtttc acaaagccca agttatggag cagctgaatc
     3481 tgcggaccac agccgaattg atcaaatatg cgttgaccca cggtttgctg gctccttcct
     3541 gatgtaactg ctaccgtgtg tctctccgca ttgtgcgccg aagctgacct cgcatcacgt
     3601 gcccctggtt ttctcatcaa aatttcatgc tgtcttcagt cggccttcat ctttgggccg
     3661 taccatcccg tctctcgcca gaagcgtcgg tttccgggaa tgcctattcg ggcagcttgc
     3721 gctgtgcacg catcgcacgg atcgatttgg gttcaaccgg tttggcgacc gagaaaggga
     3781 acagttatgc gcattgctca gatcagtcag tgtttcgagg aagtgtcgaa cgagagtgag
     3841 agaccagagg tcaggggcgt ggagttcgtg acgaggagcc tcatgcggtt tggccacgac
     3901 gtgacggtct tcgccagtgg cgacagtcga gtatcaggta gattaatacc ggtgtcgcct
     3961 caagcgattc ggcactatcc gtcgcccaag cggcatctct ccgaaggatt gacctttctg
     4021 gctatcgaaa aggcgttttc catggagtct tcctttgacc ttctccacgt ccatgcgggc
     4081 tttgtcgcct ttccgatgat gcgccgcagt cctcttccca gcgtggcgac ggtctatggc
     4141 tcgctggatg caccagaaat tttgcaattg ttcagagcgt ttcgtgaatt gcccttggtg
     4201 gcaacctccg ccgagcaaat tcgacagtgt ccggagctca attggctagc tcttattccc
     4261 gttcccggcc cccgtcagcg tagcgaagtc cctgcggaaa caatggactc actggtcgaa
     4321 acggcgacag cctatacggc cgtctatgaa agcatcgtcg agagagcggt ccggcctact
     4381 catgcagtga gaccggccta ttctctttat gacgtgcaga ctaccgtctg acgtaggggg
     4441 ggtatgtcca agccgacaac tcatgatgaa ccgcagaatg gcgtcatggg catggtgcct
     4501 gtggcgccgg gcagttcctc cgtcaatgac gaacagctgc tccgcgcttc ggctcttgtc
     4561 acccgatgtc cagtattgaa cgctcttctc tccaggccgt ggacgagcct cacgccttca
     4621 gtcaatcaga cgcagcatct gtaactgttc gtacctcgta atcttctcat acaaactatc
     4681 gggctttacg agttccgcct tccagcaggg tgccgtacaa ctcgtgtctg ggcgtggcac
     4741 gccatccgaa gatggccaga catgtctatt ggcaggaatg gtggccatga accggaacga
     4801 ttttctggtg gcattattcg ggcgccctgt ctggttccac tgcaagcaat gccatcgggt
     4861 gatggctgga ggaacggagg agtcttttcc cgacatgtgg caggaggaag cggtggccat
     4921 ggaagcctgg cgtgtgaggc ctgaagacct gtggtggttt gataccgttt gtgggtcctg
     4981 ccaagagcag caaaggagct aaatcctgtt cgacggaagt ctcgctcaga cggcaataga
     5041 gaatgtgggc ccagagctgg catatgaacg gcgaactttg cgggctcttc gccagtttcg
     5101 gatcggtgta catcgcatca tgccgacggg gctcccgcca ggattacttc gggtcatcga
     5161 tcagatcgtg tgtgtcgcgg gaacctccgg tcggggaacc gatctctggg atggcattcg
     5221 tgtcgaatgc gagcgggaat actccggcat ccgtcacggg aagggcacgt tggcgcatgc
     5281 gctcgaatgg gaaatactga agctccaaac acggttggaa agcagtgcct atggcaatcc
     5341 ggtcgttcca gtacctctct ttcgcaatcg gcacgtgcac atcgggtcgc tgatccggct
     5401 gtggcgacgg cttgccttgg agacagaaga atggctcgca agtcaggggt atgacacgtt
     5461 gctcgacgta gggccctggg gcggattcaa tttcgtgctt gaaccggacg gttacacacg
     5521 gatgcccttt gcgcgactca ctttagctgt gggtgggctg ccgtccacgc cgtttcatga
     5581 acagggtggg ccgctgttcc agcatctgct tccacggtat catgccgaat tacagcaggc
     5641 cggcgtgaac tttccccctc tctggcagta tcaccacgcc aagcatgatg cctccgtacg
     5701 cttgcgggaa gtctctgcca cacattatct gcccacgcat agttacgaac gccgaacgtt
     5761 cgtcaaagtg cgggtctcgc gagattgcga ggccgtcgag gagatcgcgt tgcaggattt
     5821 tcttcttctc ctcgagcgcc tacagttcac cacggattgg gagctctatc gggaacagac
     5881 gaaggatgtg gatgctcgct tcgatcttca ggactttatc tcgctcaacc atatggtcga
     5941 gggcgtgtat caacggaccg atgcggagga ccgacttctt cacgagatga aggacgcgtt
     6001 tcgcggagcc atccgcgcca gacaggtgtt atacggttat ctgagccagg tcgtgaaatt
     6061 gcgttgggta gagaatctat attgggcgct ggctgaggcg gctcttggcg tcaagcgcta
     6121 ccagcgcatg gtctcgttcg atcgcgaggt ctgtcctcag attccgccac gattactcat
     6181 ccccgtgcgg aggcacctga accgctacca caaccgtgtc ggcggaacgg cctgagtcca
     6241 attcaacaga ctggctacag tttggttgct tccaaggtgc cgatgctacc ggtcacctta
     6301 tgtcggcggc aacgaccgaa gcctgcctgc ctcaaccacg cttcgacctc attccagcta
     6361 tagcaccggc ctgttccagt aaatgcaaac atgagaagtg aaaagacggc cgcctcagca
     6421 ggacgggtct cctctctcgc gagaaaatac tccacaatga acagtctgcc gccaggccgc
     6481 agcgcctttc gggtacggcg aagcaagtgc cggttctccg tcttattaaa gtcgtggagc
     6541 acgttggcga gcaggactac gtcaaggtca gtgggaagcg gcagggtccg aagatcgccc
     6601 tcttgaacct gaatgcggtt cgccagtcgc tctcgacgga tcaggcgttt ggcgacggtg
     6661 acggactggt ctatgacgag accctgaagt gtgggatacc gccgggctag tgcgatcgca
     6721 taggatcctg ctccgccccc cagatccaga aatctttcgg cctgtcgagg cagtcgaaat
     6781 gagtcaatgg tcggttggac cagtatgtgg ctacgctcct gcatcgcgag tgcaaaacgg
     6841 cgccggaaat tagcggtctt ggtgacgggg gcccatccag gcgggccacg tcggattgcc
     6901 ttggtcatgc cgctccaatc cacccaatgg tgattgagga gccacagtag gttggtgatc
     6961 gcgagagggc tcccgccatc tagaaacgtc cgacccagcg gtgtattcca gtagcgcccg
     7021 gctttcaaat gaagcagtcc tagccctgtc agtgattgca gtaatagctt catgccctca
     7081 cgcaccgttc cgcacgatac ggcgagttcc tcagcgctcc gtccgcccgt gccgatggcc
     7141 gtgaatacgc caagttcatt ggcaacgagg agtgttttgg attcggcgta tccgttcgcc
     7201 aggctcatga gttgttggta agtcatagag atcgccccag gaagcacaaa cgaccgcgtt
     7261 ttcccaaccg gcaggagtca ctgtaccacc gaggataagt gagtcgcgaa tgattagcgc
     7321 cagcgtttcg gggagtcacc gagaagcgag gttctcacct tcgacctttc atccggagcc
     7381 ctgattctga tagaagcgtg ccatgcttga tgtcattggt ctcggtgcgg tcgcgggcct
     7441 cattcccgtt tatctcggga ttttcgctgc cctttatctg ggaaaggtgt tgccacgaac
     7501 ctgggagggt gggctgatcg gggtcgcgaa cggggtgctg gtctatctct tcttcgacct
     7561 catgcacgaa gcgaccgagc agacgggcgc gcgtgatccc ctctcatggc tggtgtttct
     7621 gggcagcctt ggtgtgagtt tcgtcggctt agtggctctg gaatccagcc aggtgttcgg
     7681 cgcccgttcc ggcaaccgga tcctgtcgtt gccttacatg attgcggtgg gcatgggctt
     7741 gcacaatctc ggggaaggtc tcgcgatcgg cgccagttac gccggtggtg agtacacgct
     7801 gagcgccttg ctggtggcgg ggttcggcct gcacaacgga accgagggat tcggcatcgt
     7861 cggagccgct ggaaaaacgc cgatctcctg gcgcgatgtg gcgttgctcg gcctgattgc
     7921 cgggttgccc acctgcgtgg ggacgttcct gagcgggcag ggcgtgtcgt cctacttctc
     7981 gatctgcttc tatgcgctcg ccgcagggtc gctgctctat gtggtgctct cgctcacggt
     8041 gatgtcgtac acggcgacgc gtcgggtaca agtgtcggca ggcatgttta ccggcatcgc
     8101 gatcatgtat ctgacagcca tgatattgac gctggtcagc ggcgtacgca gctgacgggt
     8161 ggcatccgac agtgtgactc atcctgcctc gtctttcttc ctacacgtat ccggatggtt
     8221 cgacttcttg ctccctcact gcgtgtcacg cgacaatagg tgagtcgcaa cggggcctct
     8281 ggtcggcgct tcaattgacc ccgcgacagt cggttgtgta taaaatggtc tgctcgatga
     8341 aagagcagat tttttcggga ggcgttcatc atggcgggac gggagtttca cgacggagcc
     8401 aaggatggct tggaggcact agagcctcta gatcccgaga agattcattc ttttacggaa
     8461 ttgttggaag ctatgcggaa gacggcgttc ggcggccgcc gactcggcga ggcctatgaa
     8521 acgctcgccg cgatgatcga ggaccctgac tgtaaagtcg tcttgaccct ctcgggcgcg
     8581 atgacgattg ccaagatggg gaagatcatt agcacgatga ttgaccgcgg catggtgcaa
     8641 gcnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnttgccaag atggggaaga
     8761 tcattagcac gatgattgac cgcggcatgg tgcaagccat tgtctcaacc ggcgcattgg
     8821 tggcgcacgg gttgagtgaa tcggtgggga aactgcacta ccgtcatgaa ccatcccaaa
     8881 ctgacgaaga gttgtttcaa aagggctaca accgggtcta cgacacgctc gagatggagt
     8941 cgaatctgaa ctatgtcgag catgtggtgt cgcagaccat gaagcgcctc aatgtcgacc
     9001 aaccgctgtc gtcaaacttt ttgactcgcg aattgggtaa gacgctggcc gaggagtttg
     9061 aaggtccggg aattctcaag agcgcctacc tcaagaacgt gccggtgtat attcccgcgt
     9121 ttaccgattc tgaaatgggc ttggacttgg ggacctgggc catgggtaag cagatcgatt
     9181 ttacccgtag ccagatcaaa gagggcgggg atgtggcggt attgcgtgcg ctgcatcaga
     9241 cctgtccggt gtttaatccc tatctcgacc tgaatcacta tgcagaagaa gttctaggtt
     9301 ccacgcggct cgggattttc acgattggcg gcggcgtgcc tcgcaattgg gcacagcaag
     9361 tggctcccta tattgaaatc agcaatacgc gtctcggtct caatgtcgag cctccgcgtt
     9421 tccactatgg cgtgcggatc tgccctgaac cggactattg ggggggctta agcggatgca
     9481 cctatcaaga gggcatctca tggggcaagt tcgtgccgcc ggccgaaggg gggcggtttg
     9541 ccgaagtgct cagtgacgcc acgctggtgt ggccgctgct catggtggga ttattggaac
     9601 ggttcgccgc gaagagtgtc tccgcatgac gcccctgaca ggttggatga tcagattcgc
     9661 cacgcccttc ctgctgctcg tgctcacgac ggcctcggcc ttggcggcga gctcgccggc
     9721 ggtcgataat cggatgcggg ggaaggcgga tgcgccgatc accctgatcg agtattcgga
     9781 cttcacctgc gggtactgtt tgaaattttt caaggaaacc tggccgaaga ttcacgcgcg
     9841 ctacgtcgaa acggggaagg tgcggtttct ctacaaagat tatcctcgtg ccgaccaggg
     9901 ccccggcgtc actgccgctc tggccgcccg ttgcgcggga gatcagggca cctactggcc
     9961 tatgcatgat cgtctcttcg ccgctgatgg ccggttggat gtggatagtt atttccagca
    10021 cgccaaagcc atcggcctcg accaatcgaa gtttcgggag tgcctgcgcg atgctccgca
    10081 tatgaaggcg attttccaag atcgggacga ggccaatgcc tggggattcc acggcacgcc
    10141 cggcttcatc ttgatgcgga cgacgcaaca gccgacggcc cagaatccgg cgctcgcgat
    10201 tcccggagcc tttccctttg ccgcatttga agaagagatc gagaaactgc tcgcggcctc
    10261 gggagagaag gcgaagtaac gccgctcatg ggcgtgaacg acagtaggtg aatatcgtga
    10321 cgagcatcat cgtctagcca cgaaagagga aactgcatat ggggtctaaa caagcttttt
    10381 ggactgtgcc tgcaaaggat ggagagccgg atctgtgggt gtgcatgtcc tgtttgagcg
    10441 aggcattttg ccgcaaggta cccatgcccg cctgtcccac ctgtcacggg gtctcgacgt
    10501 atgaagcgtt taccttggca gcggtgcagg attgggggac tgaagagttg atcgccaaag
    10561 ccgtagctgc tcagcaggaa gaggcggccc tcagcgcggc ggcctctgcg gctcctcctg
    10621 tggagtccgt gcagtagcga gtgtcctctc cgggagttgg tccgttggaa aatggacgtc
    10681 catttctaat cggcggccgc tggtctcaat ccacgacggt tgccccagta cgaaatccct
    10741 acacaggcga gacgattgcc catgtctgcc aggccagtcc ggcggatgtg gaatcggcga
    10801 tacagtcttc ggtcgatggt gcggcagcca tgcgtcgctt gtccggctat gcgcggtcga
    10861 cgctgctggc caacgccgcc caggcactcc aggcgcggca ggaagaattt gcgcgtacga
    10921 tgacggcgga ggccggcaaa ccgctgacgg atgcccgtcg tgaagtcggt cgcgccatcc
    10981 agactctctc gattgccggt gaagaagcca aacgaatcgg cggcgaggtg gtgccgctgg
    11041 attggtcgcc gggcatggag tcctattggg gcgtgacgcg acggtttccc atcggaccga
    11101 tcctcgggat tactccattc aactttcccc tcaatctcgt cgtacacaaa gtagcgccgg
    11161 cgttggcggc gggcaactcg attttgatca agccggctcc ccaaactccg ctgacggcgc
    11221 tgttgctggg cgatctgctc cttaaggccg gtgtgccgcc gggggggctc aatatcctgc
    11281 cgtgcgacaa cacgctcgcg gaacagttag tcgtcgatcc ccgcttcaag ctcctgagtt
    11341 ttacggggag cgcacccgtg ggatggatgc tgaaagccaa gtgcggcaag aaaaaggtcg
    11401 tgctcgaact gggcggaaat gccgcggtga tcatcgaacc ggacgcggat ctggagtatg
    11461 ccgctcagcg ctgcgtcacc ggcggcttta cctatgcggg ccagacctgt atttccgttc
    11521 agcgcatctt tgtgcatgaa tccattgccg agtcgtttac cgaacagctc gtggctcgtg
    11581 tgcgagcgtt ggcaaccggt gatcctggcg acgaacgcac tgtggtgggt ccgttgatcg
    11641 acgccggtgc cgctcaacgc atcgagggct ggattgacga agcgattacc cagggcgcgc
    11701 gtctgctgtc cggtgggtcg cgcgaaggat cggtcgtacg ccccaccgtc ttatcccagg
    11761 tgactgccgg gatgaacgtc tcctgccgcg aagtgttcgg ccccctggtg acgattacgc
    11821 cctatcgtga gtttgaggcg gcgttgcgcg ccgtcaacga gtcggactac gggctgcaag
    11881 cgggaatctt caccaccaac atcgggcgca tttttcaggc cttcgagcag ttggaggttg
    11941 gcggagttct ggcgaacgag attcccactt ttcgtgcgga ccacatgccc tacggcggca
    12001 tcaaagattc cgggatcggg cgtgaaggtc tgcgctatgc gatcgaggat atgaccgagc
    12061 cgaagttgct ggtcgtcaat ctccggcgcc cgtaaaggaa agcgcaggca gagcaaaaaa
    12121 acccctcccc ccgtattgcg gatgcggaac aaacttgata caactttcgc gcgaatcggc
    12181 gcatgatcac gcgcgcgacc aagggcttgt gacaattcat cgagcactca cctggagtgc
    12241 gttcgacgcg ggatgaagag ggagaccgac atggtaccaa cacacatgtt tttgacgaga
    12301 ggcgtcggag tgcacaagga aaagctggct gcgttcgagc aggccttgcg tagtgccggc
    12361 gtggcctatt gtaacctcgt cagtgtctcg tccattcttc ctcccaactg caaaatcctt
    12421 ccccgcaaac gcggcgaaaa attgttgaac cccggcgaga tcaccttttg cgtcatggcc
    12481 cggtcagaga ccaacgaacg taaccggctc atctccgcgt cgattggctt agcgattcca
    12541 accgatcgtg atacgtacgg ctatctttcc gagcaccatg cctatggtga aacggacgaa
    12601 gagtccggtg aatacaccga agacctggcg gctcagatgc tcgccaccac ccagggtatt
    12661 gagttcgatc cggatgtggc gtggaaagag cgcgagcagg tcttcaagat gggcggaaaa
    12721 atcgtccgga cgctcaacat cacacaatcc gcagtgggac ggccaaaccg ttggacctgc
    12781 gtgattgcct tggcggtgtt tatccccacg gaaaacattc ccaagagtct tcggaacaag
    12841 gcctagcggc ggcgatggcg cttccgtccg ggtggcttgg gcaagccgat aattttcttg
    12901 ggatcgacga gccctggtgc catcccgatc aggccggcgt gtatgtcctg ccggctccct
    12961 acgaacacac gtcgagttac atcctcgggt cagaccgggg tccatctgcc atcatcgaag
    13021 cttcccaaca ggttgagttg tacgatgaga cgttgcggta cgagccgtat cgcgagtggg
    13081 gtggtgtcgc tacggccaac acgctgaacc tgaacgggcg tgtcgatggt caagccgtgc
    13141 aggccattca ggattttgtg caaccgcacg tggggcgcgg gaagttcctg gtgaccctca
    13201 cgggagagca caccggcgcg ttaggtgcta tccgtgccca tgctcaacac tattctggca
    13261 tgtgcgtcgt gcaaatcgat gcccatggcg acctccggca agcgtaccag gacaatcctt
    13321 acagtcacgc cagtgtcatg gcccgcgtgg tgcaggatgg tttgccgctg gtgcaggtcg
    13381 gcatccggtc gatcagcccc gaagaaatcg agctcatcga taagacgcca cggatcaaga
    13441 cctttttcgc cgcctcgatt ttggatccgt ccggccccta cgaggggcgg gcggctcgtt
    13501 ggattcctga ggtgttggct tcctgccccg ggcctgtcta tctcaccttc gattgtgatg
    13561 ggctggatgc gtcgcttgtt cccgccttgg gaacaccgga accgggaggg ttaggttggt
    13621 acgacaccct cgcgctcgtg acggcgctgg ccaatgggcc gggcatcgtc gggatggaca
    13681 tcagtgagat tgcacccatt gaaggcttcg tcgcgcctca gttcagcatt gctcgcttga
    13741 tttatcgtat gctggggcgg gttcgggcgg gccgccgggt tcattaggcg gatggtgaat
    13801 cgctctcccg gctctcatct cacagtgctg agacgtcaga cgtacagttc gtagcatcct
    13861 ccctcttcat tcgcgcggcc gccatgcgca tcaataaatt ctttactgaa cagggcttgt
    13921 gttcacggcg tgaagcagac cggctggtgg ccgaaggccg ggtcacgatt aatggtgtgg
    13981 tggccaagct cggtgatcag gtttcgtcac aggatgttgt cgcgcgagac ggaacgatcc
    14041 tgcagcgggg caaccgtgcg gtctatctca aatatcataa gccggtcggg gtgacgacga
    14101 cgaccgaact gcacgtcacg cggaacatca tttcggaaat caatcatcgc gagcggatct
    14161 ttcccatcgg gcggctcgac aaggattcat cgggtctcat tctcctgacc aatgacggcg
    14221 atatcgtcaa cgagatcttg cgggttgagc acgggcacga gcgggagtac cgcgtagaag
    14281 tggatcgcga gttcgacgac gccttcctct cgcgcatggc agagggtgtc gtcatattag
    14341 gagagcgaac gcgtccatgc ctgatggcgc gagtagggcc gcgtcgattc aggatcattc
    14401 taaccgaggg gcgcaatcgc cagatccgcc gcatgtgcca ggcactcggc tatcgggtgg
    14461 tttcattaca tcgcgtgcgg attatgcaca tcaccgtcga agggcttcat gcgggacagt
    14521 ggatggactt gagcgaggag gaacgtcgcc ggctgttcca ggctctaggc cggccgccgg
    14581 aatcgtcgtt gtgagaggca agcggctcta ctcggcgcgg agtgccgtat tggatccgcc
    14641 tccaggcagg tccaaggagt cgggacggac ggattcttca ggtctggatg cggagagtgg
    14701 cgctctggtc gttcgactga ggaacagatt cagcaacgcg atgaaaaaac tccctcccac
    14761 aatccaataa ctggtggagc ggatggtttt cgtgccttcg tcgcgcatgt ctttggcgac
    14821 ttccgcgacg gtttccagca ggcggtccaa ggccagactt acttgcatga ctttcggtcc
    14881 gccattgtct gcggcatgga tttccgcttt gcgcctgagc tctgtcgcct cgccgggtgt
    14941 tcccgccttc cattcctgcg acaagagatc gaccgtttta ctggcgacat ggaagtattg
    15001 gtccaggctt tcacgtacgg cctgaatgtc tttttcttcg ctgcgtccac tacgggagac
    15061 gcgcaagcct gctgccgcat accgatccac cgcatgttga atgcgagcgc gttgcgccgg
    15121 aagtgattcg gtaatgcgct cgaagaccgc ctgattttcc gcttccagtg agcggatgat
    15181 ggtgttgcga tagcggatga cgtcggcgga gatgtgggcg aggtctgcgg cccccagcgt
    15241 gtattccgta tacatgatgc gcaggtcttg atcgatgcgg ctcagcgcct ggccgctgat
    15301 ccatcccagt cccgcgatca ggaggctgat gatcaattga ttcgtgctgg gaaaggacaa
    15361 tttgaaacgc gaggcaaacg acacggacgt ccctttcgtc gggccggaaa cgatgtgcat
    15421 ggcccgggag gttgaaggat tcagtctagc agatcgtgcc tcaagaaaga aatcgacgcc
    15481 ggttttgcga caaggcccat caatcgagga tgacgcggcg ctcgaccagt tgcccgactt
    15541 cggggtcatt ggacacgaac acaatggacc agggctcctc tttagcgcag agccttcgca
    15601 ggagagtcag tcgcacggtc gggtcgatat tgtggaggct gccgttgaaa atcagcaatt
    15661 ccggacgggt cacgatcatc ctggcgagaa ggatgcggag cacctggctg cggctcaagt
    15721 tcgccccgtt cccatgcacg accgtttcca gccccagggg cagcgcgtcg atctcctcct
    15781 ccagttccac gaatcgcagc gcccagctca gatcggcaaa ttgaatcgat ggacgctgga
    15841 gggtcacatt ttcctccagg gttccatcga agagggtggg atgggaatcg agcatcaggc
    15901 ctctgcagcg attcacataa ttgagtgaca cgtcgcgcag gtcgatgtcg ttataacgga
    15961 tgacgccgct ggtgggatga tagagcccgg ccaggagaag cgcgagggac gttttgcttt
    16021 tgctcgtgcc cgtgagcaca ctgatctttt cgcccggcag cacttccaga ttgaaatgat
    16081 cgaacagcat cggtccctca gggctggcaa aggacacgtc tttgcacgtc agtcgtactc
    16141 cctgcagagt gggattcggc agccaggcgg cgatgggacc ggagacctcc tctttcggca
    16201 tttcgaacag cctggagagc tcctgcatgg atgtggcgac gtagatagcg gcgtacatgc
    16261 gacgggcgac gatgtcgaga ttgagaagca gggtgccgac aatgacctcc gccgcaacga
    16321 attggccgag ggtaatgtcc gcgagggaga gtaaccatcc gccgaggccg atcatgctgc
    16381 tatgggcgat ggcctgaaag atgaccgtac tcttgtattg cgccccggtc agaatatcgg
    16441 atcgggtctt cctcgccatg acataggcct gcacgagcgc atcggtcttc ttgagcagaa
    16501 gcggcaggct gtcggtagat ttgaaatgga gccggttgat gccgatgtcc tgcaaccagt
    16561 gaaacgtctg gtagtgaagg ttggagactc gttgagtaat ccggagtcct ccgcggccaa
    16621 aaaaggtcag aagaaaagca aatccggtga tcaggaagat gttatagccg aggaagtagg
    16681 gatggtacat gatcaggatc gtcatgccga tcatgcccga cacgaacacg ttgatgatgt
    16741 cgaccagcat cgcgaccagc gcacggggca acagctctgc ttcgatgaag gtgttggtgt
    16801 gttgcggaag gaagacgttc tcccggaacc ggggcagggc ttcggtaaag gcgacagcca
    16861 gcctagtata gatccgctgc accaggattt ccaccgcgcg tccctgcaag acccggaatg
    16921 cccccatcaa cagcaacgcg cctaacatga tggcgaccag cgtcacgatc atgatcggtt
    16981 gaatggcgaa ggcgaaggtg ttcacgagct cttgcacggt gagcggcacg atcagcgcaa
    17041 acagaccgat cacgactgca taagaggcaa tgatggccag aatgcgccgc tcgagttcga
    17101 ccaggaggtt gagacgcgaa agaatcgtcc aggctgaagg tgtggtgatc gttgattcgg
    17161 tagcgatggg gttcacgcga tagctcgtgt cgaccgatgg tggggcgcag tgtgggcgaa
    17221 tgccgcatct ctgtcaagaa cgggaaacac ggtggtcggc gggtgggaaa gaagcgagag
    17281 cccgaggcca gcagcctagg tgacggtgtg gcaggccgtt agttcagcat gatccggcgg
    17341 tcgacatgcg gggtgagatt cggatcgttc gagacgaaaa tcaccgacca gggttcttcc
    17401 ttgctgcata agcggcggag aatcgtctcg cgcatcgcgg gatgcatgtt gtgaagaatg
    17461 ccttcgaaaa tgaggagctg cgggcgtcct agaatcgctc gcgccaccag gatgcgcacg
    17521 atgtgcgtag gggcgaagat tttacccgca gaccgcacat gtgttttcaa gccatggggg
    17581 agggcgtcga cttcttcttc cagttcggtg aagcggaggg cccaccgcac atcgctatag
    17641 ggaatgtagt cccgcccgag cagaatgttt tcttccagtg tcccctcaaa caacgagagt
    17701 tgtgaatcca ggatgaatcc cctgaagcga ttgacggaat ccaggttgag atggcgcaga
    17761 tcgacgccgt tgtagcggat gacgccggct gtcggtgatt cgagtccgcc gagcacccgg
    17821 gcgagcgcgg ttttggccat cgtcgtatcg gcatagatcc cgattttttc accgggcgtc
    17881 acttccaggt tgaagtgctc aaatacgggc gggccgccgg ctggcgcaaa cgtgaggtct
    17941 ttgcacgtga ctcgaatgcc gtgcaccgtc gggtcgggca agggaatgga cagcgtggcg
    18001 gcgtcctgat ctttgggcaa cgagaagagg aagctcaatt cggtcaaggc ggtgagaaaa
    18061 taatagatat gccccatccg cttcacgacg ccgtcgaagc ttgagaggat gccgctgacc
    18121 acgacttccg cggcgacgaa ttgtccgagc gtcagctggc cgattcccag gagccaacca
    18181 gccgttgcga tgaggccgct atggacgatc gcctgccatc cgagtgatcc cagatattgc
    18241 cggatgagaa tgccgaagcg ggttctgcgc accccgacat agttgtccag gagttgatcc
    18301 gtcttcttga tcagcagcgc ctggctatcg gtggacttga aatggagcag gttgtacgca
    18361 atttcctgaa accagtgcag ggtgtcgtat ttggcgtggg acatgtccat gtcggccttc
    18421 agcccgccat ggctcatgag aaagaacacc acgttgaacc cgaccagcaa gatggcgtta
    18481 aacaacagga agtacgggtg gtagaacacg aggatggtca taccgaccgc cccgccgacg
    18541 atgacgttga tcaagtcgac cagcagcacc gatacggccc gctgcatgag aatggtttcg
    18601 acgaagtaat tggcgaatcg aggcttgaag ccctgatacc gcaaatgcgg caattgttgg
    18661 gccatggcaa tggccacccg ggcgaagatg cgccgctcca ggacttccac cgcataatat
    18721 tggagggccc ggaaggcgcc gacgaagagc aggcccgcca ccatgaccgc ggccagtgtg
    18781 acaatggtga tgggctggag cgcgaaggcg aacgtattga cgagttcctg aactgtgaga
    18841 ggaacgatca gcgagaaaag cccgatggcg atggaatagg aaacgatgag accgaggatg
    18901 cgccgttcca gacgaaacag gaggcccaga tggccgacga ccgcttgaaa caaattgctc
    18961 tggttgtcgg aatgatcctg ggacatcctg ctacccctgc cgcgcctcat caacccatcg
    19021 gccgtgttgc ggcgatggcc ggatgatgat tgttgcggcg gcctgtccgc gcaggcctac
    19081 accagctaaa acctatcaga gcgcaccgta aaatactact atttggacaa gctcgcaccg
    19141 acccggtagt tgaccggaac ggctgagggc tggctcctgg cccaagatcc cgtcgcccat
    19201 tgatagaggg cgagagcctt ctggtaatcc gccttggccc ggacgagttg catctccgaa
    19261 tcgacggaat tccgctcccg caggttcaca aacagcacgc tcgttgcgcc caggctgaac
    19321 cggaaacgtt caccttcttc caaggtcttg gccatgcgaa gtgattcggc cgccgccgcg
    19381 acccgttcct tcgcccgttc gatggccgac acggcattgt cgacatccac gaccacttgc
    19441 tgttcccgat atttctgcac cagcaccagg cgatcggctt gcgcctgggc ctccatcact
    19501 tcaccccggc ttctccgttg aaggatcggg atacgcagct cggccccgaa ccgatagccc
    19561 aatcccagca caaatttctc cggagccctg gccggcgccg cttccagatc gagactcggc
    19621 aggagattgt tcttggcgag ttccaaatcg atattattga ccttggcttc gatatcgact
    19681 tcgcggatct ccggccgatc atttttcgcc tgcaacttat cagctttgat gatgtccgct
    19741 gtcggcgcag cggcgggagg gggaaagtct ggaacgcgct cgagctgcgg ggtcgtcggc
    19801 gtctggtttt cccagaggaa catcgacatt ttatattgtt cctgctccac ggctcgctgc
    19861 gcggcgatgg agatttcacg gcgacgctgg acttcctggc ccgcctcgac gacgtcgagg
    19921 ggggccacgg ctcccgcctt ggctctgcct tccacctgtc tcaaccgttc ctccgcgacg
    19981 ccgagggccc ggcgttgcac gtcgacaaac ttggcggcgg agacccagtc ccagaattgg
    20041 ctcgcggcgg ccagaaagag atcctgtctg gtttgcgata ttttgacctc ggcgcgagga
    20101 tcagccagct ccgaacgctg caactccgcg ttttcggggt tgatcatgag ccctttcaac
    20161 agaggcagaa agccgccgag aatgacctgc tggttaccgt ttccgaaaga aaggtcagga
    20221 atcttcgcat cgccgatggc ctgtcgaacg cccgcgctcc cgcggaatcc ccatggggtc
    20281 cgcgcttcga ccaaggtatc gttgaatccg acgctctggg ttttggaggt gctcttgtcg
    20341 atgaaccgct cgatctcggt atcgttcacc aggaccggtt cgaatgcgcc gagggccttg
    20401 agcattttcc cgcgtgccga cgttttttcc gtaccggctc ccttcagaag gggatgcgaa
    20461 cgatcgatcc aggcgtgaac ctcgttcaac gacagaggaa taggcggaag ggtttttgct
    20521 ttacccgtat cctccgcctg ggcgctgctc tctggaagtc cccagagtgc acaagcggca
    20581 atgaccagga tccatgcata gttcttcatg aaacgcactc ctttctgagg tcacaagaca
    20641 gagaataccc gtcgaagggt gtccgtgctc cggcatgcgc cggggagacg ggaccggtta
    20701 cttggccccg cgaccggctt tcggcaggag ggtatcgatc aggcttggag gccgttcctg
    20761 gtagtcgggc ggaaagagat tgaaccggcg ccagagctcg taccagagcg ggacgcgatt
    20821 gagaatgacc catcccatgg ccttcgtgcc ctggcggacg tgttcttgcg gaggccaggg
    20881 acgttcttcg agatcgggaa cgacccagaa gcggaaatta cccttgccgt cgtcgacctg
    20941 gtcgatgacc ttgatgaccc cgttgtacgt accagccatc atttccggcc aggcgggcag
    21001 ggggatggcg ggaatgccgt agaagagaat tttgaccttt cggcccacat tgagtaacgg
    21061 ggcatcgatg ccgtcggcca ccatttcaat ggccctgtcc acactgttcg gagaaatcct
    21121 gaccagtttt tcaccgggcc gcacggtttc gccggcgccg gcctgcgcca tttttacgac
    21181 ggtaccgtcg atgggcgaga gaatccggct ggcaacccgt cgttgattcg cgttggacag
    21241 acgcagagaa acatccgcca cctgatcggc ggcccgcgcc gcttctccga tcgaggcatc
    21301 tcgcgcggct tctgcgtcaa gcagccgttg aaggacttcc gcgctgacct gttcccgtcc
    21361 gaaactcaaa gccttcatgc cctgttcggc ggcagccagg ttggcttgtg caccctgcaa
    21421 atccgccttg ctggcgatgg cggcttgaat cgtgagttct aattcgcgct gggagaccag
    21481 gccctgttgc gccagctgtt gatgccgttc cacattgagt tcggctgtgg ccacggcgat
    21541 cttggacgct tcgatttttt gccgcgcctc acgcactttg ctttccgctt cgagcacccg
    21601 cgcgcccgcg gacggaaccg cggccttcac gaggttttgc atttccttga tacgtttatc
    21661 gagttgatcg gcgcgactga gggcggcttt ccgcgtatct tccagcgcct gcttgcgctg
    21721 ttcgaggagg ttcaagagat ccggagccat gaagttcggg tcgtagtcgt ccagttcgag
    21781 aatcacgtcg cccgctttga cccgcacacc ttcgaagatg tgccacttcc tgatgcgtcc
    21841 ggtaatctgt gcttcgatgt cttgcggacg ttcaaaaggc gtgtaggcgg agagctggcc
    21901 ggttaccgta atcgtttgcg tccacgggac gaaagccacg atcaacatga agaagccgac
    21961 caggagaatg gccagccgtg aagagaaccg caatcgttcg ggaatttgga cggcttccca
    22021 ggactggagc ttggtggacg tggccagatc atcgacggcc atttcatcca agcctgtacg
    22081 ctgggtgacg agggagcgaa atcgggtttt gagtccctca cggatacgct gcacgtaacc
    22141 cctccacgca ccgtccactg tagagatgcg cacccgtatc atagtggaag acaaaggagt
    22201 tggtcaattc aatgaggcgt tccgtcgtgc ttcggcttga cccttcgacc ggagaagggc
    22261 tatggttcgc cgcatcattc tttccttcag ccagaggtgt cgtgtccatg ccgaagaaga
    22321 agcgtgcgga tcgggcgttg gtcggggtct tgggcggcag cacatcggac tttcccatcc
    22381 ttgaaaaggc cgtggccatg ctgaatgagc tcgggattcc caacgagctg ctcgtcgtgt
    22441 cggcccatcg taccccggat cgcctcttcg cctatgcgga acaggctgtg gcgcggggga
    22501 ttcaggtcat cattgccgga gccgggggag ccgcgcatct tcccggaatg gtggcggcga
    22561 agactctgtt accggttatc ggcgtgccta ttcccactga acatctccgg ggcttcgatt
    22621 ctctactgtc gattgtccag atgccccggg gaattccggt cgcaacagtg gcgatcggcg
    22681 gcgcggaaaa tgcggccatc ctggcggcgc aaattctggg agtacagtcc gcttctgtca
    22741 ggcaacgcct cgaacgattc cgtgccgcgc aaacacaaaa ggttctcgat tcccaggatg
    22801 acgcccggtt gtcccctccc ttcccgatgt cacgcgggac caggacgagc cgcaggccgt
    22861 gaatgtcacg gtgattgatc ccggcgcgac cctgggtgtg cttggtggag gccagctcgg
    22921 cgccatgttc gccaccgctg cccgccgcat ggggtacgcg gtgaatgtct gggaccccga
    22981 tcctgaagcg cctgcccacc ggatagccga ccattcactc attcgcccgt tcaccgacgc
    23041 tgacgcccgt aaagagttca ctcaacgggt tcgtgccgtg acctatgaat gggaaaacgt
    23101 ccctgccgac ctctgtgagc aattggaatg cgagctgccg gtccgtccat caagccgggt
    23161 gctccgcgtg attcaggatc gcattgaaca gaagacgttt ttgcggagtc gcggattgcc
    23221 cgtgccggtc ttcgcgacac tagcgtcgcc ggaggaactc ggccggcaga ccatgcctgc
    23281 ttatccgctg gtgtgtaaga cggctacggc cgggtatgac ggcaaagggc agtggaaaat
    23341 ccttcgagcc gaagattgtc cggcggtgca acaggagttg gcccgtactc ggaggcctgg
    23401 ttctcgatgg attttggaag aatggcttcc gtttcagcgt gagctatcga ttctggttgt
    23461 gcggggtgcc gacggcgcgt cgcaaaccta ccccttggtg gacaatgttc atgaagaggg
    23521 cattctccgt cagacgatcg tgccggccga tgtgccgcag ccggttgccg acctggccgg
    23581 caccatcgcg tgcgacgccg tgcaggcgct tgacggggtg ggggtatttt gcgtggaatt
    23641 gttcctcatg gccgatggcc ggttggtgat caacgaaatc gcccccaggc cgcataactc
    23701 cggtcactac accttggatg cctgtacggt ctcgcaattt gagcagcagg tgcggacctt
    23761 gtgtggcctg ccgctcggag agatccggtt gctcagtccc gccgtgatgc tcaacctcat
    23821 cggtgaggat gttcgactcg tgacgcactc ccctgcagcg caggatcttc tccgcgtgcc
    23881 cggtgcgatc gtccacctgt atggaaaacg cacaattcga ccaaagcgga aaatgggcca
    23941 catttcattt ctcgctccta cgcgcgcgga ggccctcacc gccgcgtcga ccttccgctc
    24001 gcggtttgct ccgattcact cgtaaaaaaa cgacagcagg cgcgatcagg tttaggctcg
    24061 gtgtgcgtct ggatggtatc cgtttctgtc ggttgagatc gttcggccgc tctcagactg
    24121 tccgtttttg tgagacgggg agaggtcacc ggccgttcat ggccaccctt cattctcctc
    24181 ctcctgaaat tgcgaagact tgccaggatg gcaagacggt atgggacttg ctgtcatccc
    24241 cgctggtttc acacttctct ccgaagggca ggcacagcgg tgagcgttcc actttcctcc
    24301 gatctcgatc aaaccgggcg gcatcccacc atgcgaggac tgggccgatt gttctctcat
    24361 tcgcgagtcc gcgtgatgtt tctgcaaagc ctcgtggccg gcattctgtc ctatgaattg
    24421 cttgtgagca acgagacgat ctatgggcag aacgtcagcc ggatggtggc gctcggattg
    24481 atgctgatca gtatgggaat catcttgttg ccgaaagcgg cattagagag cacctggttt
    24541 cccggcgcat tgatcagcat caataccctg ctcgtgacag ggaccattta cctctccgga
    24601 aatgccagct cggaattgta tctcacgtat tttctactgc tcctcattgc ctcctctgcg
    24661 ccttcactga aacaattact cggcctctcc gtcatcatct gtgccggata cggcatcttg
    24721 gtctatgagc atgcgatgca gtccggcacc ctggcggtgg ggcacctgct cggtattcct
    24781 gttttgctca tcatgtcggt gttttacggc ctcacgctgg aaacagtggc ggtcgagcgc
    24841 cggcggaacc gtctgttgcg ggaagatgtt caggggttga aacagtcgga gcaggttctg
    24901 gaggaacgac gaacgcaact ggaaacccgc gtgcaagggt tgaagcaagg gctgtcgcgc
    24961 gccaaccagg aaattcgcca aggcatggtc gaacgcaccg ggctggagcg gcagttgcgc
    25021 gaagcgcaga aattcgaagc gatgggacga ctggcctcca ggttggcgca tgaattcaat
    25081 caggtcttgg cggtgatcgg ggctcagacc ggggccatcg tttcaaagtt gaaacccgat
    25141 gaccccctgc atgggccggt ggaagacatc ttccggagcg gagagcgtgc ggcaaccctc
    25201 accgcgcaac tgctcgcact gggcgtgcac gaaacgagca ttcgcgacac cttgtcgctc
    25261 ggcgaggcga ttgtgtcgat gcgcgaggcg ctccaggcac tgcttcccgg gcggattgat
    25321 gtgagggtac ctgacgagtc caagccggtg ctggtggaaa ttggtcatga ccggttggag
    25381 tgcctgttgt tgcacctggt ggcgaatgcg cgagatgcca tgccgagcag cgggcgggtg
    25441 gatatttcgc tggaagtggt caccggagag ttgttaccgg cagagcaact cgaaaaaaat
    25501 ccccggaagc ggatggcccg cattgccgtc agtgatagcg gcggcgggat gaatctggac
    25561 gttcaagccc agatgttcga gccgttcttc tcgaccaaag agactcatgc cggtctgggg
    25621 ctcacgttgg tgtatggaat cgttcgtcaa tgcggtggaa cagtggaggt gcaaagccag
    25681 cccggacaag gcacgacggt gcgtgtctat ctgcccctgg tcgagcggaa cgccgtgctg
    25741 cgtgacagca gggtcctccc tgaggcgctg tcgaagggcg ctgaaacggt gctcctcgtt
    25801 gaggaagatg aaattgccag gaagctggcc ctgtcgacct tgcacggcca tcgctaccat
    25861 gtactcgagg cggggtcggc agtggaggca ctgcttgtcg cgcaacaata ccaaggaccg
    25921 attcacctca ccgtcagcca cctttcgatg cctgaaatca gtggccggga gttggccaaa
    25981 cggttggtcc tgcaacatcc aaaaatgaag gcgttgttcg tgtccggatt ttccgacgag
    26041 acgattgcca gtcatcgagt gaatagaaaa tacttcctgc agcagcccta ccggcagcac
    26101 gatctggcgg ggaaagttcg tgaattgctg gatgtctaag cgaggaatcg cgacgctagt
    26161 atcgaaatga ctcggtgcgg ccgggtttga aaaatcgtac ctccgggcgc ttaaagaagc
    26221 cgatcagcac catccctgcg ataaatccgc cgatgtgcgc aaagaaggcc acgcctcctc
    26281 cctgcgagcc caggctcgcc ccaccgttca gcaactgcat gacgaaccac aagcccagca
    26341 cgataccagc cggcacgtag gtggcgccca ccaccggggc gatcaacaag acacgggcat
    26401 ggggaaagag cagcagatag gcccccagca cgcctgaaat cgctccgctc gcaccgacca
    26461 tgggaaccgt cgatgtcggg tcggtcaagg catggctcaa cgccgccagg attccacatc
    26521 ccacatagaa gacgataaat ctgacatgtc ccatgatgtc ttcgatgttg ttcccgaaga
    26581 cccagaggta cagcatgttg ccgatcaagt gcatccagct gccatgcaga aacatgctcg
    26641 tcagaacggt cgcatacgcg ggtatgcgtg tcagttccgg tgggagcacg gcctggccga
    26701 acacgagtga ggggatggcc ccgtattggt agacgaaggc ttcaccggag gttgacccga
    26761 gggagctttg gtacaggaag acgagtgagc aggcgacgat gaatgcgacg gtgacgacag
    26821 gcgtgcgttc ggtcgggtta tcgtcactca ggggcagcat cgcaacacct gaaacacaag
    26881 ggctatgagg cggccggtcg cggcagccga ggatttgcct gggggaggcc gtcggcctgc
    26941 agcggcaccg aaaatccagc cgcatgggta tggccaccgc cgccgaagga tgcggcgatc
    27001 gcgccgacgt cggtgccctc ttcgcgggaa cgcatgctga agtatcggcg accgttacga
    27061 tcgtgccaga tcacgcaaaa cggatgctcg gcggacaacc gttcgccgat ttgactggtg
    27121 aggacggagc tctggaccga cggcacggtg gcgccttcaa actccaccag cgtcgcgtgg
    27181 gaggccagtt tcgtcacgag ttcgttttcg tagcggagaa tggcccggcc ttcccgctcc
    27241 aactcgcgct gttcgaaacg cgtccagagc tcgaagtcga acgggtgtga cgccagtgct
    27301 gcgctgattt ccctgctgtt cggaagcgcc cagtgccata aatccttgtc ttggatgtag
    27361 cggagcaacc agggggccgg ttcatcgtgg gcccattccc agcccagtac tgcgcccgac
    27421 ttgttgagat cgaaatacgc gtaggggagg tcggccagtg cctgttccgc agtgatgtga
    27481 tggtccagaa cgaccaggct ggccgcatcc ttggccatgg cttccaaggt tgagcggttg
    27541 tagctgaaat ccaccatgac aatatgatga ccggcgaggt tcgtcggcgg cgcttcgccg
    27601 tgtttcacgg ggcgatactc cgcgtcggga taccggcgcc agatggccca ggcggcgccg
    27661 aacccgtcgg cacattccgc gtgatacagg atcagtgtgg gaggagagga agacagggtt
    27721 cgcatggtgg ctgcgctcat aggccaacca ccttagcatg tccgttcatg gagactaaag
    27781 agctatctca ggattaggcg agccggcgtg gctgccggct tcgcctgcat tcgctcaggt
    27841 ggtcgccggc agatgattga ggtgattgat caattgcctg aggcggcctg cattgcggcg
    27901 attgaaggaa aatgtcagtc gtgcaagatc tttcaatccc ggctcgtcaa tttcttcggg
    27961 gagtgagggc cgttgctcga acgtgccttc cgtcagcatg tctttgaatt ggtgctgtac
    28021 ttcttggact tgctccgcgg tcaagggggt cttcagtctg atggcgagct ggcgtcccac
    28081 gaatcggagg gagtgatagc gccgataaaa cgtgcggatt tccgtgaccg catcttccac
    28141 gttgtcgacg atggtgaaga gggaaaggtc ttcggcgttg atcagacggc gcttgagcag
    28201 ctgatcggta ataaaagagt tccagtggtt ccaataatcg cagcccggcg cctggaggca
    28261 cacgatcggc ttcggatcgc tcttgccggt ttgcacgagg gtcatgatct caaacccctc
    28321 gtcatgggtg ccgaacccgc ctggaaagag cgcaatcgcg tgtgactctt tttgaaacat
    28381 gagcttgcgc gtgaaaaaat acttaaacgt gacgagtttg ggatcatcgg cgatcacggc
    28441 attggcgccc tgttcgaagg gcagcatgat gttcaccccg aagctgtgtt cgcgaccggc
    28501 cccttcctgc gaggcccgca taatcccatc ggcgcctccg gtgatcgtca tgtagccctc
    28561 ttccaccatg cgtcgggcga actgaaaggc cagttgatag ttcggatcgt cggcgggcgt
    28621 gcgggctgag ccgaagacgc tgattttcag tcgatcgcga tatccttgaa acacgcggaa
    28681 ggcatgccgg agttctttga gcgcccggtt gacgatcttg aggtccagga catccagttg
    28741 cgattcagag agccggatga cgccggccag gatctctttc atgagcgcgg cctggacatc
    28801 gtcgtctggc cgatcgagca gggtggtgat ttgtgtaaga atttcgtctt tggtcggaac
    28861 gggtttggaa cgagcggcgg gagttttcat caatagtcac ctaacgcacg gtaaactccg
    28921 gacgggcatc gccggagaat gaaatcataa caagccgggg agctcgaagc aaaagattca
    28981 tcgggaggaa cttaggagag atccgaggca cgcggcaggt tttgcaacac ccaggcccga
    29041 attttcgatt cgtcggacga cgagagggac aagaattgga tatcgatgcc ggaataggtt
    29101 cccagcacgt tccggtcttc gtggaattcc ggctcatagt tgctgttgag aatggtgcct
    29161 tgcagcgaga agctcaagtc cgttccggga agaatgaacg acagcacgat actcgttccg
    29221 ggaagcagta atgtgcgact ttcgatcgac gcgccgacat ggctgagctg ccggattgtg
    29281 gcggtatgtt ttgccccttc gccttcgccg ttggtcacgc gaatggtggc gggaaggcag
    29341 gtctcgcagc gtttcggggc cagggccagg tcgcgtgcag tcaggatgcc gaccggttgt
    29401 ccttgtttgg tgacgatcag gagggaggtg ccggtcgagg ccatgacgct ggtggcatcg
    29461 tcaagaatct ggtcacattc gacggaatgg accggcttcg acatgatgga ccgcacctcc
    29521 acatcgtgcg gttccagacc ctgggcgacg acttttttga cgatgtcgcc ggaggtcatg
    29581 atgccgaatg cggcctcacc gtctttgacc agcaggcagg gcatctgttc ccgatcgagg
    29641 agcgaggcgg cctcgctgac agagacgtcc ccgggaatct gtaccacgcc gggtgtcatc
    29701 atatgggcca ccataggggt tgtcgtatga gtcggtttgt cgcggagtat ggagccggtt
    29761 cttgtcatag tgtaagccta tttctcgccg tgagaggggc taacggtgcg gcccggcgac
    29821 caccacgtcg aaagaaagta tatcagatgg atgtgccgga cccgtcttcc catcttccct
    29881 tgtcaaccaa gaggttaggc gcttagactg cacagaaact atagtcacta tggttgcttc
    29941 aaaatatgcc aaatgcgatc cgatgaaaag cgaattcaca gaacgtgcgc atcgccttcc
    30001 tgcacatggt ctcgggctgt ccgtggacgt gtattccccg gacctgctgg agctggtccg
    30061 tgcacttcgt gatgcagcgc tggagccgga ctatctggag attttcaaag ccacgacgtc
    30121 tgcccaacaa tggatgcggc aacaattgcc ggatctcaag ctgacctatc atggtgaggg
    30181 gttgtggagc acgcaaccgg aattctgccg cagcggttcc ggccgacagg gagtggcgga
    30241 agcctgtgcg cagctcgcgg cgttgcgcag cgcctggctc aatcacgaat gcgccacgaa
    30301 gcagatggcg ggttatgcgt tcgggaccta tctgccgcca ctctatacgg agttgtcggc
    30361 gaggatgact gcggagaatg tcgcctatct ccaaagccaa gtggatcagg atgcgcatag
    30421 gcgtgaaatc gatcctgcgc tggtactctt agagatgccg ccgctcacgt acttcggctg
    30481 cggcgcgctt ccaattccgg attttttccg tgcggtcacc gatcaggcat cctgcggctt
    30541 ggtgttggat atcggacatc tatggaccgt gtatcgctat acaggaagct ggcaacgaca
    30601 gcggttggaa gagttcgccg cccagttcct tgatgcgttt cccatggagc gggtcatcga
    30661 gatccatgtc gcaggactgg ccgaactgac ggttcctcac ccttctggaa ttgacgcgag
    30721 cgggaatgca ttaccctatt ggattgatgc gcacggggct ccgatcccag gcgtcttgtt
    30781 tgatctgttg gcgcaggtcc tgtctcatcc cgggctgaca tccttgaaag gcgtcgcact
    30841 cgaggtcgat acgaagccga ttgcgatgat cgtcgaggag ttcaagcaat ttcgagaacg
    30901 atttggaacg acggttcaag caatgctcca tcgtgacagc cctgcgccag tgcaaccgca
    30961 gcgatcgccg aatgctcgtt cggctgagcg acggcaactg acttcggaag aagaagccac
    31021 attgcagcaa cagtacctgc actatgtgca actcgtcacg acacaagatg atccctcctc
    31081 tataaggaac ctctcgttgc taggcgggtc gctggacgat ctcaaccggt atcgcgagac
    31141 ctacctgccg catgaattgc tccattgggg cggcgaattg caggatatgt ttccggacac
    31201 ctgtcgtgcc ctgacggaaa gtgatgtgcc gttggatcgg tttgttgcgg tctggttcag
    31261 caaacccaga cccgagcagg acgactatga ttttttcctg ctgaagatcg accgattcgt
    31321 ggaattcgcg acacacgcgt gtccgatggc tgccatgatc gtgatgcgtg aagccgaaga
    31381 gctacgggca gcctatcgcc aggcgaacga accgatcggc tcatcccagg tgcgcgcatg
    31441 aatttttgga cgacgctccc gcagcccatt ctcggtttgg ctcccatgga cggggtgacg
    31501 gatgccgcgt tccgtcgcgt ggtggcctct caagggcggc cagacatcac gttcaccgag
    31561 ttcaccaatg tgaatgaaat ctgccgcggg ccggaccatc tgctgtcctc gctaatttac
    31621 agcgaagccg agcggcccat tgtggcgcag ctctacggta aagatccgga gcagttctat
    31681 cgcgcggccc aggtggtctg tgagctgggg tttgacgggc tcgatatcaa tatgggctgc
    31741 ccttcgaaga gtgtggcggc gtccggttca ggggccgcgc tgatcaagac gccggatctg
    31801 gctcatgcca ttctgcgtgc cgcgaggcag ggattggagg attgggccgg tgggcagtcg
    31861 atccaccagc agggatttaa accctctcgc attgaattca ttcacgagct gaatcaccgg
    31921 cgttccggct ctcccgtggt gccccgccgg ctgcttccgc tttccatcaa gacgcggctg
    31981 gggttcgatt gtgtggtggt cgagcgatgg gtggaacact tgttggaagt tcgcccggcc
    32041 gccattacgg tgcacggtcg aacgttgcag cagatgtacc gcggtgccgc cgactggacg
    32101 gctattgccg aggcggccag ggtggcccgt gatacggaaa ccttgattct cgggaacggc
    32161 gatctcaata cattggttga tgctgttcga cgtgccgctg acagtagggt gcagggcgtg
    32221 ctggtggggc gtggaaccct cggcgcgccg tggttctttc gtgaaaagga gcaggcacgt
    32281 cgcgcgttcg tcgaacaggt cgatctgtca acgcttcccg ccacgatgtg ggaaccgccg
    32341 gtgtctctgc gtcaccgcat gcaggtcatg ctggaccacg cgcggcagta tgaggcgatt
    32401 gccgggttgg agtgcttccg ctccatccgg aaacatctcg ggtggtactg caaagcattt
    32461 cctcacgccg cggccatgcg ggggaaaatg ttcggagtct cgaacgtgca ggatgtcgaa
    32521 cgcatcgtcg cagaattttg ccaggacctc atactggaag aagctgccgg atctgatgcc
    32581 gctcccatag ctcctcaatt cccatacccc tgtgcatcct gactccatgc gattgattct
    32641 ggcttccacc tcgccgcgtc ggcacgaact attgactctg ttaggggtgc cgtttgatgt
    32701 cgtcgctccg cccttcatcg aacaggtcca gccccacttg tcggcagact cgcaggcggt
    32761 agaatttgct gccggtaaag ccaggtcttg tgtgtcttcc tgtcccgatg ccctcattct
    32821 cggaagcgac acgctcatca atctgggctc tgaggtgttg ggcaagccgc tcgatttagc
    32881 cggcgcggag gtgatgctcc gccgtctggc cgggcagacg caccgcattg tgacagccgt
    32941 ggccctggcc gggcctgagc ctgagcgatg cgacgtccgg ctggcagaag tgctcgtgac
    33001 gatgaaacct ttgaatgaag ccacattggc caactatctg cggactggcg atagcctggg
    33061 taaggccggg gcctattcca ttcagggagg cggggctgca tttatcgagc gcatcgaggg
    33121 cgatttcacc gcggccgtgg gattgccgct gcagcttgtc gctgagatgt tacggcagcg
    33181 tggactgtcc tgtccggtcg acatcgatca actgtacgcc agcagaccct atcccaactg
    33241 ggaccgcttt cgtccttagc caggccacgt cggtcacacc ccttctcacg tcccgccaga
    33301 ttgaaatggt cttcccaatc cttttacaat gcgcccttgt tcagtgacgt gtcagggagg
    33361 tactcatgcg cgtgaatgat ggcagggtag gtcggcgtgg gcaaacccat gcggtggtcg
    33421 ggttggtgat cggagcgatg gcattggcaa tcagcgggcc ggcgtgggcg atcgacgtca
    33481 agttgtcccc cgaagacgcc aagaaggccc tggaagccgg gcgagcgccg atggaaaaag
    33541 cggcttcgcc ggaagatgtg aagaaaatct tgcagcaggc ttcgctggtc acgcgggttg
    33601 gtgcggatcc cgaaaaagac ccatgtgggg ccagcgccat tctgcgcacc aagcgctacc
    33661 gcttagaggc gttcggcagg caggaagcag cggaatcgaa aaaacagaaa aaagatgtgc
    33721 gcatgcccga cgagtttatc cagaaagtcg tgga
//
LOCUS       DAOQPD010000039        33367 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_570_length_33367_cov_23.140820, whole genome shotgun sequence.
ACCESSION   DAOQPD010000039 DAOQPD010000000
VERSION     DAOQPD010000039.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 33367)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 33367)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33367
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_570_length_33367_cov_23.140820"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..2813
                     /locus_tag="PK063_10510"
     CDS             <1..2813
                     /locus_tag="PK063_10510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97527.1"
                     /translation="APWLEPIHQDANGERTSEPALPGEQGRWSLCPDNANRKHYNIHF
                     VRMPITLAKKQGKEPAMVDKDGLIYVLHEEERLTRANDDLKLPAVIRANVYDCVDLLL
                     TSEWDDDDYTNFQSSKINIHPHFFQFDTGNSDGVISGMEYEMSVRPFTMWGKKTKHGL
                     PAPMVAKLTGEAKAGATSIKIQMAPGATAFHVNTELMVGMDCLEKGNDPAASLPRDKS
                     CQEVARVKEIKGDVVTFFKPLKNHHPAGDLVSPEFVRYRWWVDVDMGTVFWHDHAFGA
                     TTWPHGGFGVTIVEPYGSTYHDPKNGKLVYSGPVADIHSNEPIGAGVSGSFRELMVSI
                     HDTVPHTVNVIEAGNPPGQPIEVALEAGKTVSFQMPDKILNAPNKYINGGTHTTGSGF
                     NFRAAPFAQRLSNNPDTSKLFSSAIHGDPGTPLLRAYTGDTMVFRLLHQLMNESHVWT
                     IAGHTFLTERYAPDANRKNSIHVGIAERYDLVTKAGGFQGMPGDYIHFNGRTSHFAEG
                     GWGIIRVLDKETADLKPLPRGTNPLGIPATPNSVCPSDAPVKSFNVVALDRPMKLNPK
                     APDAIEVDFERKIEMTMPEGKIFALEEEAATVAGNVMPNPLTLRANLGDCIKVNLKNK
                     MKASRASFFAPGLAFDPKDSQGLNVGNNAGDQTVAPGESRTYTYYAHPANKETTSLVW
                     DGGNIVVNPRNGLYGAIVIGPRGSQYRDPVTGADVSQKNTWRADVIVDTTLSENAGKR
                     NYRDVALFFQDEDNIIGTAFMPYVQNVAGLTSVNYRAEPYKFREEQGCSLGKIFQPCA
                     VDKPEDPVTPLIEAHAGDALRIHVIGANSEQNGMFSVEGHEWPIEPYMAGADMISVVE
                     YAGSETLDIFIRGGAGGPYRQVGDFVWSNARLPYTQSGQWGYLRVLPTGDSRIQPLSA
                     SGAGARQAEVLPEPQAIPTAMK"
     gene            3014..3964
                     /locus_tag="PK063_10515"
     CDS             3014..3964
                     /locus_tag="PK063_10515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase-like regulatory
                     domain-containing protein"
                     /protein_id="HMZ97528.1"
                     /translation="MTHRISGWKVGLAAMALGGLLASHPASAYEEITVSDGGTLSGVV
                     KLEGTVPKPKGYNLTTLPDPYYCGRISDGEGWRILQPFNVGPKGEFREVVVYLEGIEK
                     GKSFAEKEVPQIEAKDCLFLPFTTVVRDDQSVTVVNMDPVMHDIQAYETSNLGARVLF
                     NVPLPMNPQHPRNFKDRTEAGMYHKHMAGPPMKELVKLSKGRRIFVMQCGFHAYMESW
                     GVAIANPYFAKTDEEGRFTMTDVPPGTYKLVVWHPYIRTATEKIVTIGPKGTVETTIG
                     VPAPTGRLYANEVLDHAYTRYNVTEEAKKEIDPLLQKQEH"
     gene            4002..4934
                     /locus_tag="PK063_10520"
     CDS             4002..4934
                     /locus_tag="PK063_10520"
                     /inference="COORDINATES: protein motif:HMM:NF015722.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HMZ97529.1"
                     /translation="MGIWRGGCLRALLGCVAIGLLPGLVTPSHADHELPKPPPLWSPL
                     DNVERLALIDVPNGMAEVPAGPFLMGSDPKFDRAAGPQELPQHQVYVDAFSIDRYEVS
                     NVNYLRYVLATGAAWPHYWREQPFPEKMAKHPVIGVSWREADAYCRWRGARLPTEAEW
                     EKAARGEDGRMFPWGNEPAGWIKSNIAHPGSKRGAKYPPLANVDRYDNGVSPYGVHQL
                     AGNVSEWVSDWFDPEYYRRQENRNPQGPASGQDKVFRGGSWNEDPEVARSAGRNSGGL
                     DHWSYLTGFRCATSGESGRQLSSIDPAMGRNTDR"
     gene            4966..5925
                     /locus_tag="PK063_10525"
     CDS             4966..5925
                     /locus_tag="PK063_10525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
                     /protein_id="HMZ97530.1"
                     /translation="MKRLQKGKRKRTRLAQALVIGAALFALAPIARALDTQDIVVEWT
                     EEGKKIAQERVANWKTKDEMVLVPAGEFLMGSDKKTDRLAYRSEIPQRSVYLDAFMIG
                     KYEVTALEYLKFVLATDRLPQLDWRYDGGNFQDTMAHHPIMHVSWYDADAYCKWAGKR
                     LPTEAEWEKAARGVDGRLFPWGSEYAGPTRANFGRTGLSGPVRDRPERLLLYPPIISV
                     DKYENALSPYGLYQTIGNVAEWVSDWYDQDYYKTAPARNPKGPETGTQKAFRGGGWMD
                     STTTMRAAMRNGTDPKTKINWMGFRCAQDAKEDTGTKVSMTKE"
     gene            6395..6967
                     /locus_tag="PK063_10530"
     CDS             6395..6967
                     /locus_tag="PK063_10530"
                     /inference="COORDINATES: protein motif:HMM:NF012257.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HMZ97531.1"
                     /translation="MKRKPCLIEHCDTCGLREKVVLCDISGSDLQEFQKIKRTLEYAP
                     HQTVFYEGHLCLGLYLLCSGKVKLTRSSTRGRRQIVRILGPGELIEKHVFGDRALHEV
                     TCETLEPSQVCVIDKERYLAVIHRNPQLAIKLIQLLSNEVGVNMDHLDQFTFKTARER
                     LAGLLLELGDRFGKKKTIKFESVSPSSVKK"
     gene            6973..7104
                     /locus_tag="PK063_10535"
     CDS             6973..7104
                     /locus_tag="PK063_10535"
                     /inference="COORDINATES: protein motif:HMM:NF024934.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HMZ97532.1"
                     /translation="MAGITVETTIRLLGVFRDEGVLTIDGRTITLLNPDRLSRIAER"
     gene            7414..7962
                     /locus_tag="PK063_10540"
     CDS             7414..7962
                     /locus_tag="PK063_10540"
                     /inference="COORDINATES: protein motif:HMM:NF013936.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043169 - cation binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemerythrin domain-containing protein"
                     /protein_id="HMZ97533.1"
                     /translation="MVPQGSRRTSLLVDPLALLKREHHMILERLAMIETAMSPCCSGS
                     GAVKQTNRDTLRDLLEFFTGPVDVHFKREEMLVDNLRRTLGRNREEKEQFQSFVEEHQ
                     ALKDDATAVMQQLARKRSDGQDGVEPKACGGLRALTDELHRLIRRYREQIACEERLLF
                     ALAEMRLTADQRRRISQRMLQV"
     gene            8205..8906
                     /locus_tag="PK063_10545"
     CDS             8205..8906
                     /locus_tag="PK063_10545"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97534.1"
                     /translation="MKRVRKVVQNIGMWGAGVAIAAVLGVAGVQPASAEEGTGNMVFF
                     KGGFMNLNQDRSGQIFTDTAGIAGANGGNAGWYAGAGLDLVMSKDVWGGMDKTWVLGE
                     IGLQFNSINSSRVNNAAGSIATRTLTDTLATDPQKVQLTMVTIDVAPKIKFMEGSAFR
                     PWVIPVGLDIHVISPPSNRTQYLDLGVQFGAGFEYAVWKAFKVGVDARYHLTARLTNT
                     NNDYFQVGPYVGISF"
     gene            9007..9552
                     /locus_tag="PK063_10550"
     CDS             9007..9552
                     /locus_tag="PK063_10550"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97535.1"
                     /translation="MASFRIEISGGRALVDITLYLPDDSSLPFPIGEHSPQQAFAHRI
                     EETGSGLHHVVTFTGLPEHIDLALQAIGESVRIPGAWAAVGGQRMSSLVALWNRLDCY
                     RQSLSCSDRVSYCRNKAASVRVGLGCGLAFCSAPCQFLCPLCSLKDTPLAQSIVHPET
                     QVLVVLGEIDWCPNLARPADR"
     gene            9626..10099
                     /locus_tag="PK063_10555"
     CDS             9626..10099
                     /locus_tag="PK063_10555"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97536.1"
                     /translation="MFALVWIHLLAAVVWVGGMVFLSVVLVPVLKRDGGFARHAALFR
                     TAAYRFRALVWGAMGILVATGSVLAAGRAIPLSDPSQWPSIFMTKIGLVAFLFTLTLL
                     HDLVVGPQVRRILGTAEAARSAKDRLLVRYSVLVPRVSLLVALLVLLAAVVLART"
     gene            complement(10183..10908)
                     /locus_tag="PK063_10560"
     CDS             complement(10183..10908)
                     /locus_tag="PK063_10560"
                     /inference="COORDINATES: protein motif:HMM:NF017077.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHASE3 domain-containing protein"
                     /protein_id="HMZ97537.1"
                     /translation="MILYETHLTWLRRILAGKGLIIALIVGFLAVESIVAACFLSLMH
                     FKTSNNWATRNEQVLIELERVRSIVSGAETHQRGYLITGSDNYLAPYREALDMLQEQI
                     RRIGSLTRDNNLQQDRVAYLATQVDQRSDEMEQAIALRRTKGLPGAKSIVTQNQLNRT
                     MDTIHDITEQIRDEEARVLARNRADSEAWALTTGSLALVFFLLNAVVFALCGVVMKLA
                     LSSHAQTERLVDALRPSTTPATR"
     gene            11221..12468
                     /locus_tag="PK063_10565"
     CDS             11221..12468
                     /locus_tag="PK063_10565"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014960295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HMZ97538.1"
                     /translation="MARVVIIGASIGGLPAAYEARELLAKKHKVTVISNVESFHFVPS
                     NPWVAVGWRTRKDISFALGPVLEKKGVEYIHATADRIEPEQNRVITSKGEVPYDYLII
                     ATGPKLNFGAVPGLGPSGYTQSVCNVDHAEQAWGTYQAFLKDPGPIVVGAAQGASCFG
                     PAYEMAFILDADLRKKKLRKKVPIYFVTPEPYIGHMGLAGVGASRRLMEDEFAEHAMK
                     PMCNTSIKEVQPGKMVLEGGQEIPFRYSMIIPPFAGVDAVAGTPGLCNPKGFVNIDAY
                     QANPKYKNIYSVGVCVAIPPVEQTPIPTGAPKTGYMIESMVSAAVHNIKADIDNDTKR
                     ETATWNAICLADMGDTGVAFVALPQMAPRNVTWAKKGKWVHLAKIALEKYFLRKMKKG
                     VSEPYYEKVILKAMGIAKLEEPA"
     gene            12489..13286
                     /locus_tag="PK063_10570"
     CDS             12489..13286
                     /locus_tag="PK063_10570"
                     /inference="COORDINATES: protein motif:HMM:NF014035.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HMZ97539.1"
                     /translation="MIEQALRAVVSGVPIGLQLGATGTGGAILGVPLMVYIAGMSLQQ
                     AAAMSLMIVGASSLVGAWEYGRQGMVKPKAAAAFSWTGMIGSWGGAFVHHMIRQEILL
                     VLFGLLLLLVRTVMARQRELAAEHGADESCATLFPRTCWMKVGGIGLMVGTLNGLFGV
                     GGGFMVVPALILVLGFPARAAIGTSLMIIFMISIGGVVGHMQFGHVEWSLLGYVLLGS
                     VTGMVLGVRADTWVSPVVMRRVTASITISIAGILIVVNLAKLAGWLG"
     gene            13488..14441
                     /locus_tag="PK063_10575"
     CDS             13488..14441
                     /locus_tag="PK063_10575"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97540.1"
                     /translation="MVTPERTAQAEWSAIAEQKTSYTTDAFQFSSARRLRLTEDPSLP
                     TVVSTDKPQDVIWEPALEVIHSTPTMQGKNELSVKAQGAIYTNNPIFNHSDFRIQDRF
                     SLDQATSVLVRYRYIPNLFLGPNFERRTGTRSVQEERVSSHHWRAEVERRLSDTVTAT
                     LITRFGIRRYNDVFAERDTNLWTVGSRVDYRAKEWLTLTLSYLYERGLADGHKETQFA
                     DDVSYYLHMVSAGTEFRLHKEWDLGLTYIHRRKTFTSGIAGDSHVDRFDATHQGIAEL
                     RYHISTAATAMLSFQYGKRTSTNVLRDFQDSIVSIGGQYRF"
     gene            14560..14748
                     /locus_tag="PK063_10580"
     CDS             14560..14748
                     /locus_tag="PK063_10580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2892 domain-containing protein"
                     /protein_id="HMZ97541.1"
                     /translation="MKLNEMLRLIAGVFVLIAVVLGATVHPYYNYFAAFVAANLIQSS
                     FTGWCPMMALLRRLGVHE"
     gene            14777..15823
                     /locus_tag="PK063_10585"
     CDS             14777..15823
                     /locus_tag="PK063_10585"
                     /inference="COORDINATES: protein motif:HMM:TIGR01730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HMZ97542.1"
                     /translation="MLALLLAAGCGPSQEPGKPGNMTPGTAGQEPIQVPVIEVAASQV
                     PISVEVTGQVTAVYQATLASRIQGMIDNLLVREGSVVRQGQTLVVLDNRDVQAELSRV
                     TAELDNAKAHQDRMEELYRKDAVSKQELENATRALRVAEAGRKAVLAQLSYTIVKAPF
                     DGVITEKKVERGELASPGQPLLKMEDPGRLRLEATVAESDVRVVSVGSLLPVVIDALG
                     ANPLKGTVSQILPAGDPQTHTFTIKVDLPQAGGLKSGMFGRLKLEKGMSTTLLLPKSA
                     LIERGELASLFVVGGDQTARLRWVRIGRTLEQGVEVLSGVDAGERVIADGSKGRDGAL
                     VQDMTAVALPPQAR"
     gene            15892..19167
                     /locus_tag="PK063_10590"
     CDS             15892..19167
                     /locus_tag="PK063_10590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HMZ97543.1"
                     /translation="MTTPRLGASGRLAALFVGSKLTPLIILASLLLGLFAVLLTPREE
                     EPQIVVPMADVWLPFPGASAKVVEEQVTKPIERKLSEIKTVEYLYSISRPGGALIIVR
                     FYVGEPMEQSLVDLYDKLMSNQDLLPPGAAPFQVKPRDVNDVPIVTLTLSSERYTDFQ
                     LRQLGDQVLEDAKKVPGTASGFVVGGRGRELRVQIDPTRLKAYGLTPLRVASVIQGEN
                     LALPAGRFESRNESFLVETGRFIRSKDDLDGVVVGVNEQRPVYLRQVAEVVDGPSETN
                     QYVWFGEGARSSSSSSGETPAVTVAIAKQAGTNAVTVAQGVIRKVEEMKGRLIPADVQ
                     VTVTRDYGETADEKANELLWHLLVAVVAVVVFLGLTLGFRPAFVVSIAIPLTLALTLF
                     ISMLIGYSINRVTLFALIFSIGILVDDAIVVVENTYRHLTLRLLPHREASLFAVDEVG
                     NPTILATMTVIAALLPMAFVSGLMGPYMRPIPVNASIAMFVSLLVAFIVIPWFCQTCY
                     RPGVHMAGVDHDSFEEGRSYRLYRRLLAPVLSHPVMAYLVIGVIGLLLAGSVLLFWTR
                     DVVVKMLPFDNKSELQLVIDMPEGTTLEETARATKALTQYVRTIPEMRDYQAYVGTAS
                     PFNFNGLVRHYYLREQPHEADIQINLVAKDRRQAQSHDIAQRIRPPVQDIGRLYGANV
                     KVVEVPPGPPVQSVLVAEIYGPEYDRQIEIARDVRRMFETTAGVVDVDDYLEAEQVKY
                     VFSVDRAKAALAGIPSEEIVRTLRLALEGADVGLVHIPKERRPVQVKLRLPIIERTGL
                     EHLGEIALRTTAGHMVPLSELIRVEQTVREQAIYHKNQKPVVYVIADVGGTGPDKGES
                     PVYGVMGIGKKLEQYRLPEGYRLEQQYAVQPWSEQRFAMKWDGEWHITYETFRDMGLA
                     FAAALVLIYLLIVAQFQSFLTPVVIMAPIPLTLIGILPGHWLTGSYFTATSMIGFIAL
                     AGIIVRNSILLVDFIQHQEAEGIALLEAVIRAGAIRTRPILLTAAALMVGAFVIILDP
                     IFQGLAVSLLFGVGASTVLTLIVIPVLYYLWIGERRPVSACPLPQADNPAAPRHAVGN
                     QPG"
     gene            19383..21071
                     /locus_tag="PK063_10595"
     CDS             19383..21071
                     /locus_tag="PK063_10595"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF014425.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 39 protein"
                     /protein_id="HMZ97544.1"
                     /translation="MGSVGHEQEAPLLSWCEADTRRYVQMLVLALVSGWAYFANLHLS
                     LLEGSEGLYAGIAGEMARRGEFFDLTYQGIPYFNKPPLFFWLLNLSTSIWGDHEIALR
                     LPGSLAAVGTILLTYVLGTQLMSSRAGFWAALVVATSHVFLWYGRRVLFDSTLTFLVT
                     LALFAWIQVQILGRSSRWYLVTFLSMALGAMLKEMHGFFLPLLIMALYAVIQRDARMV
                     RDRFFWIGLAGAIALLAWYSQLLSVGYQHHFLLGSAIKSVWNSGLSGAAGTSKDGHPL
                     YWYLGMMWADFFPWCALLPSALLLLWQQRPLRAHQTELVLLVWVLGLFTAFSLATLKR
                     EPYLTTVVPGIGLMIGYFYHRSSQSSDGSRTMSPVLRLFLVVLALVFIGGMFFGAAPL
                     RRRWLVSAPVVSPLFIVIMVSLGGALLYAAITSRLQLALRMVGVLAVAYVVLVVNYVF
                     PAIDEAASPRKATEYIKSVAKEAGPPMFLFIPGWPKNEDAVYYLKRDTVVRDLPDEDA
                     VHHAVRTQGPIRVITEESHMVTLQKQAGLVVETLQEFLQPGRKHLYLLSIQPKG"
     gene            21389..21817
                     /locus_tag="PK063_10600"
     CDS             21389..21817
                     /locus_tag="PK063_10600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97545.1"
                     /translation="MHPIHPMVVHFPIALLLASLLFDLVALRWRGEEFRATSLSLLAL
                     GVLAALVALLTGHLAEEAVEHSGTIPKQAIETHEELAFVVFWLFAGLLGVKMLSYWGW
                     MRERSLLVLFLGVGGSVLLLVASYYGGELVYRYGAGVLPR"
     gene            21814..22995
                     /locus_tag="PK063_10605"
     CDS             21814..22995
                     /locus_tag="PK063_10605"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HMZ97546.1"
                     /translation="MKMIGALTRMVVAMAVIFGAAPVSAEKSDGRSPLGERAVLRAGQ
                     VVQGDYFAFGPQVEISGIVNGDLYAAGGEVIVDGVVNGDVIVAGAKVVLSGTIAQDAR
                     VAGAHVTVSGTIGRNATLAGADVHLTEKATVRENVIAGGGSVQLSGAIGRDARVGAWH
                     ATFSNEINRDVIVAAESVRLTSKASVGGRLRYWGEVAPSIDEEAVVHGPITRRPLPEG
                     WSTERARQGLVGMRVFAAIASFLSTLLLGLIMLRVWPQLVRQVTGAIRERPAPSVGWG
                     LAALIVTPLVAISFVVTLVVLPAGVMLLALYGVAAYLARIFAITYAGQLFVRRQDDSS
                     SLARPFVVGLLVYSLLTLVPVIGGLVTLFTVMAGFGGLLVAVKQRLAVRQEQDLVQDT
                     A"
     gene            23097..24143
                     /locus_tag="PK063_10610"
     CDS             23097..24143
                     /locus_tag="PK063_10610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HMZ97547.1"
                     /translation="MSDVGPAERALRVMDWPADGSLQFEGSGIHALDTGGAVVLSRAV
                     RDAQRRGCDVTVEGLRSEHAQLMNLVSVHWDAMMAHVAARPKGTARLQSVIRNLLDRF
                     LRGLGFIGESAMALLRVGSSPTHLRWRSALNSLRLDGVNALPITGLLTFLIGVVIAYQ
                     GAEQLRKFGTNIFIVDLVGISLLREIAPLIAAILIAGRSGSAYAAHIGTMKVTEELDA
                     LRTFGLSPTELLVLPRMLALIVALPLLTVYADVLGVFGGMLIAANQLNVSFTAFLARF
                     EEAVALRHFLIGVGKAPFFAVIIALVGCYQGFQIRGGVDDVGRHTTMSVVQSIFLVII
                     FDALCSIILNWWNL"
     gene            24380..25186
                     /locus_tag="PK063_10615"
     CDS             24380..25186
                     /locus_tag="PK063_10615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HMZ97548.1"
                     /translation="MSLAAHTETPIIDVRHVSTRFGPTVVHQDVSLTVRTGEVFAIAG
                     GNGCGKSTLLREIVGLLTPTAGRISLLGADSRDLQETDGGSLYRRFGVMFQHGALFSS
                     MTLAENVAVPLREHTSLSARLIRDIVALKIALVGLPPDSGVKFPRELSGGMRRRAALA
                     RAIVMDPELLFLDEPTAGLDPMIAAGFDDLVLDLKRLLGLTVVMVTHDLDSLWRIADR
                     VVVLGEGHVLGMGTMEQLAASEDPAVRNYFHGPRGRAVQLNHSGGESHRD"
     gene            25197..26159
                     /locus_tag="PK063_10620"
     CDS             25197..26159
                     /locus_tag="PK063_10620"
                     /inference="COORDINATES: protein motif:HMM:NF014523.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MlaD family protein"
                     /protein_id="HMZ97549.1"
                     /translation="MEPKVNYVVVGAFVLLLGATVLGAVLWLGKTDYRGIYDRYYVYT
                     RESVAGLSVDSTVKYRGVDVGRVKEVILNPDNSEEVRVTLDIVGGTPVKTDTQAVLVT
                     QGLTGLVTLNLTGGSKDAPPLTSVAGQVYPVIQSVPSLYGRLDGTLAKLLSDQGLSNL
                     VANVNGLAQNASLFLDEQNRAQFRQILKDLGEVTKVLAARSSQVDRGAQHAAEAAERT
                     ARLTEHLGVQLPALLDRMGKSAAALQHMTAEVTRTSREVGDMVGTSKPGIEQFSRQTL
                     ADAGLLVSELRQLTATLTRVAQQVERQPNVLVLGRQGQPKGPGE"
     gene            26170..26817
                     /locus_tag="PK063_10625"
     CDS             26170..26817
                     /locus_tag="PK063_10625"
                     /inference="COORDINATES: protein motif:HMM:NF015823.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-type transport auxiliary lipoprotein family
                     protein"
                     /protein_id="HMZ97550.1"
                     /translation="MLRSRVTGWVGLVLAVYTASGCVLPRSEDSAVRTFVLMREETDR
                     QAAPAGAPAGMHGVLVVAVPQAAPGFEQPRIAYLRRPSEVSYYANHVWADSPSRMVLP
                     LLVRSLDTTGLWRTVVPMPTGIKGDYQLDLSGLVVQQEFLQQPSRSRVQVRAHLVDVK
                     AQRVLGARNFEALEPAPSEDAYGGVLAADRAVATVLATMNEWIASCLRGSGRETC"
     gene            26863..27351
                     /locus_tag="PK063_10630"
     CDS             26863..27351
                     /locus_tag="PK063_10630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97551.1"
                     /translation="MVYGMRTALKVGFSFGLTSGVITTLGLMVGLHAGTHSMPAVLGG
                     ILTIALADAMSDALGIHVAEESKNHGNTHDIWASTAATFVAKFVIATTFAVPVLLMPL
                     DLAIVASLLWGLTLLALLSYALARAQRVPPWKVIGEHVIIGLCVVAMTHYVGEWVRLT
                     FG"
     gene            27381..28655
                     /locus_tag="PK063_10635"
     CDS             27381..28655
                     /locus_tag="PK063_10635"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HMZ97552.1"
                     /translation="MDIKTQLPKVGIGRRCGAIEANLGGYRSLMSDDEYEELTALAKS
                     LQGIKICHVNSTAAGGGVAELLARYIPMLQALGVQADWRLIHGEPEFFAITKAFHNAL
                     QGGHYGLGTTEQDAYLKVNERSAQALGNDYDLYIVHDPQPAAIRHFAGSRDAKWIWRC
                     HIDSSAPDKEVSRFLRPLLEEYEAVVFTMSQFVLPQLAARRVAFIAPAIDPLATKNME
                     LPIDLCRRVIADSGVDPARPLLLQVSRFDPWKDPLGVVRAYRLVKEEIPEVQLVLIGA
                     MAGDDPEGWEILDRVEEEAANDPDLFVFTNLAGVGSMEVNAFQHGCDVVIQKSLREGF
                     GLVVSEALWKEKPVVAGNTGGIPMQFPEPFQRNLVDSVEACAERVRHLLHHPGARAEF
                     GRAGREHVRRHFLMPRLVRDELRLIKQVLNAS"
     gene            28652..30355
                     /gene="glgP"
                     /locus_tag="PK063_10640"
     CDS             28652..30355
                     /gene="glgP"
                     /locus_tag="PK063_10640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucan family phosphorylase"
                     /protein_id="HMZ97553.1"
                     /translation="MMQQNDKARVAYFSMEIGLNPLMPTYAGGLGVLAGDTIRSAADL
                     GVPMVGVTLLHRHGYFYQRLDRTGRQSEEPVAWAVTDFAEPLDAHVSVEIDGRNVQVR
                     AWRHLVTGMSGHTVPVYLLDTDVPENSSWDRTITDALYGGDAYYRLCQEMVLGFGGFD
                     LLRALGQGDIFRYHLNEGHAALLVLALMESAIGTAPVNGEVPPEVIEKVREQCVFTTH
                     TPVPAGHDQFPADLAHRVLGRRRCELAQACQHQGALNMTLLALRGSRFVNGVAMRHGE
                     VSHSLYPGYPIHSITNGVHAVAWAAPSFQNLYDRHLPDWRYDHLSLRYAISIPSSEIW
                     AAHREAKLALVDEVNRETNAGFDRDVLTIGFARRATAYKRATLVFQDIARLQRLMKAK
                     GQIQFVFAGKAHPQDEAGKDTIQRIHGMRGQLPVAYLANYDMTLACLLCAGVDVWLNT
                     PLPPMEASGTSGMKAAMNGVPSLSVLDGWWVEGHIEGVTGWSIGDKVEACLAPGSDME
                     ACHAAALYDKLEQQVLPCFYQDRERFIDIMKHTIAINGAFFNTQRMVQQYLRNAYRLV
                     G"
     gene            30379..30915
                     /locus_tag="PK063_10645"
     CDS             30379..30915
                     /locus_tag="PK063_10645"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97554.1"
                     /translation="MAQPHDSMQSDYSHLLTLWTAGVRDYHTMLSDYLTANSIFVAVI
                     GLLVSRESLAVPFTLVIVLLSAIGILMSVQMAIVLGRFSGQNALWEWQLRGIESMPDW
                     RERKPVSMLYRLREHRETIVDETNEPRSFEPSWAFRQHRQWWAHRAISFPWFFGTVYG
                     LFLLWAVTQMARSSMMFW"
     gene            31139..31813
                     /locus_tag="PK063_10650"
     CDS             31139..31813
                     /locus_tag="PK063_10650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013804409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ97555.1"
                     /translation="MRILVIEDDADLAQFLRKGLEEERHTVEMVADGETGLMLAVDES
                     YDLLIVDVMLPKVDGLTLCRRLRERGNRSPILLLTARDSVEDKVAGLDAGADDYLTKP
                     FAFTELVARIRALLRRGGPHIGSRLKAKDLEMDPASRRVWRGGKDITLTSKEFSLLEF
                     LLRNRDIVLTRTAILERVWGLNYDPMTNVVDVYIRSLRVKIDRDFDVPLIATVRGVGY
                     KLEAGE"
     gene            31810..33234
                     /locus_tag="PK063_10655"
     CDS             31810..33234
                     /locus_tag="PK063_10655"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ97556.1"
                     /translation="MSSFRAQFRLYTVALIAVLLGGFNVVVYTGFHSLLQQYVDGRLF
                     GFADTLAELIEQRPELLKRSDHEIVVPRGAQVPDDRMKELREVSHSVHILSLDGTVVW
                     QGSGVVPRPSVDEAVLARGKRGEVVYETLEMESGASVRQVFVPIRQQDEVRYLLQAEE
                     SLAFFRRTHRSLMGLLMLGSVAVLATSWFGSGWLARKVLDPVEALSRTAEGISESALR
                     SRANLNAPFEEFERLAQAFNAMLDRLQRASESQRRFTDYAAHEMKTPLTVMQGNLEVA
                     LQRARSAEDYRDVLVSNLEQVQRLIVLTRSLLTLARFAGERPPVELSQLALQPLLKEL
                     IDDLTPVAEDRQVTLRLEEEPVPPMLGDAERLKQVFINLIDNAVRYTDPGGTVALRLS
                     SSKNLVRVAVRDTGQGIASEHLPHLFEPFYRTDPARARDSGGHGLGLPIVKEIVEAHH
                     GAITVESEVGKGSVFMLTFPAIQS"
BASE COUNT         6475 a         9127 c        10608 g         7157 t
ORIGIN      
        1 gtgcgccatg gttggagccg attcaccagg atgcaaacgg tgagcggacc tccgagccgg
       61 cgttgccggg cgaacagggt cgttggagct tgtgccctga taacgccaat cggaagcatt
      121 acaacattca ctttgtccgc atgccgatca ccctcgccaa gaagcaaggg aaagagccgg
      181 ccatggtgga caaagatggt ctgatctacg tccttcacga agaagagcgt ttgaccagag
      241 ccaatgacga tctgaaactg cccgccgtca tccgcgccaa cgtgtatgac tgcgtggact
      301 tgttgttgac cagcgaatgg gacgacgacg attacacgaa cttccagtcg tccaagatca
      361 acatccatcc ccacttcttc cagttcgaca ccggaaattc cgacggtgtc atctccggga
      421 tggagtacga aatgtcggtc cggccgttca ccatgtgggg gaagaagacc aagcatggtt
      481 tgccggctcc gatggttgcg aagttgaccg gcgaagcaaa agccggtgcg acctccatta
      541 agatccagat ggcgcccggc gccaccgcgt tccacgtcaa caccgagttg atggtgggca
      601 tggattgttt ggagaagggc aacgatcctg cagcgtcact gccgcgggat aagagctgtc
      661 aagaagtcgc ccgggtcaag gaaatcaagg gcgatgtcgt cacgttcttc aagccgctga
      721 aaaaccacca cccagcgggc gatctcgtgt cgccggagtt tgtgcgttat cggtggtggg
      781 tggacgtgga tatgggtacg gtgttctggc atgaccacgc gttcggcgcg acgacctggc
      841 cccatggcgg gttcggcgtg acgatcgttg agccatacgg atccacctat catgatccga
      901 agaacggcaa gctggtgtac agcgggccgg tcgcggacat tcacagcaac gagccgatcg
      961 gagccggtgt cagcggcagc ttccgtgagt tgatggtttc catccacgac acggttccgc
     1021 acaccgtcaa cgtcatcgaa gccggcaatc ctcccggaca gccgatcgaa gtggcgttgg
     1081 aagcaggaaa gacggtgtcc ttccagatgc cggacaagat cctgaatgcg ccgaacaagt
     1141 acatcaacgg cggtacgcat acgaccggta gcggtttcaa cttccgcgcg gctccgtttg
     1201 cacagcgcct gtccaacaat ccggacacct cgaagctgtt cagcagcgcg atccacggtg
     1261 atccgggcac gccgctcctg cgggcgtaca cgggcgacac catggtgttc cgcctgttgc
     1321 atcagctgat gaacgaatcc cacgtctgga cgatcgccgg acataccttc ctcacggagc
     1381 ggtatgcccc ggatgccaat cggaagaact cgattcacgt cgggatcgcc gaacggtatg
     1441 acctcgtgac caaggcgggt ggattccagg gtatgccggg tgactacatc cacttcaacg
     1501 gcagaacgtc acacttcgcc gaaggtggat ggggcatcat ccgcgtgctc gataaggaga
     1561 ctgcggactt gaagccgttg cccagaggga ccaatcctct cgggatccca gcgactccca
     1621 attccgtgtg tccatcggat gccccggtga agagcttcaa cgtcgtggcg ttggatcgtc
     1681 cgatgaagct caatccgaag gccccggatg cgatcgaggt ggacttcgag cggaagattg
     1741 aaatgaccat gccggaaggc aagatcttcg cgctggagga agaagccgcg accgtggcgg
     1801 gcaacgtgat gccgaatccg ctcacgctgc gcgcgaatct gggcgattgc atcaaggtga
     1861 atctgaagaa caagatgaag gcgagccggg cgtcgttctt tgcgccgggt ctggccttcg
     1921 atccgaaaga cagccagggc ttgaacgtcg gcaacaatgc cggcgaccag accgtggctc
     1981 cgggcgagag ccgcacctat acctactacg cgcatcctgc aaacaaggag acgacgtcgt
     2041 tggtctggga cggtggaaac atcgtcgtca atccgcgcaa cggattgtac ggcgcgatcg
     2101 tcatcggtcc gaggggatcg cagtatcgtg atccagtcac cggtgccgat gtgtcacaga
     2161 agaacacatg gcgggccgac gtcatcgtcg acaccacctt gtctgaaaat gccgggaagc
     2221 ggaactaccg tgacgtggcc ctcttcttcc aagatgagga caacatcatc ggaaccgcct
     2281 tcatgcccta tgtgcagaac gtggccggtt tgacgtcggt gaactaccgc gctgaaccgt
     2341 acaagttccg cgaagaacaa gggtgctcct tgggcaaaat cttccagcct tgcgcggtcg
     2401 ataagcccga agatcccgtc acgcctttga tcgaggcgca cgcgggtgac gcgctccgca
     2461 tccatgtgat cggagcgaac agcgagcaga acggcatgtt cagcgtcgaa ggccacgagt
     2521 ggccgatcga gccgtacatg gcgggtgccg acatgatcag cgtggtggag tatgccgggt
     2581 ctgagaccct cgatatcttc atccgtggcg gtgcgggcgg accgtatcgt caggtgggag
     2641 atttcgtgtg gtccaatgca cggctgccct acacgcagtc cggacagtgg ggctatctgc
     2701 gcgtgttgcc gaccggcgat tcgcggattc agcctctgag cgcaagtggt gcgggtgcac
     2761 gtcaagccga agtgctgccc gagccgcagg cgattccgac tgccatgaag taagcaggca
     2821 cgtcatggcg taacaccgga tgggggagct gcctgtatca cgcagctccc ccatctgcgt
     2881 tttgagtatc gaagaaggaa ttcagtgatg ggttccctgt atgattacga tgagaggtcg
     2941 agcatacaac aacccatcac agaggaggcc ggttgtgaca ttgggtatta cagcaacgaa
     3001 cgagcagcaa cacatgacgc atcgtatttc tggttggaag gtcggcttgg cggcgatggc
     3061 tctcggaggg ctcttagcaa gccatcccgc gtcagcctat gaagaaatca ctgtgtcgga
     3121 tggcgggacg ttgtcgggag tcgtcaagct cgagggaacc gttccgaaac cgaaagggta
     3181 caacctcacc acgttgcccg atccctatta ttgcggtcgc atttccgacg gagaaggctg
     3241 gcgcatcctg cagccgttta atgtcggccc caagggagag tttcgcgaag tggtcgtcta
     3301 tctagagggg atcgaaaagg ggaagtcgtt tgcggagaaa gaggtgccgc aaatcgaagc
     3361 caaggattgc ctgttcctgc cgtttacaac tgtcgtgcgt gacgatcagt ctgtgaccgt
     3421 cgtcaatatg gatccggtca tgcacgatat ccaggcgtat gaaacgtcga acttgggcgc
     3481 gcgcgtcttg ttcaacgtgc ccttgcccat gaacccgcag catccacgga atttcaaaga
     3541 tcgcaccgaa gccggcatgt atcacaaaca tatggccggt ccgccgatga aagagctggt
     3601 caagctcagc aaaggccgac ggatctttgt gatgcagtgc ggcttccacg cgtacatgga
     3661 aagctggggc gtggcgattg ccaacccgta ttttgccaag actgacgaag aaggtcggtt
     3721 taccatgact gacgtgccac ccggcacgta taagttggtt gtgtggcatc cctatatcag
     3781 gaccgccacg gaaaagatcg tgacgattgg gcctaaggga accgttgaaa ccacgatcgg
     3841 cgttcccgcg ccgaccgggc ggttgtatgc caatgaggtc ttggaccacg cctatacccg
     3901 gtacaacgtg actgaggaag cgaagaaaga gatcgatcct ttgctccaaa agcaggagca
     3961 ctaagttggt cgcgcaagga gcacgtctga tcagcaaggc aatgggtatc tggcgaggtg
     4021 ggtgtctccg ggcgctgctg gggtgtgttg ccatcgggct gctgcccggc ttggtgacgc
     4081 ccagccacgc tgaccatgaa ttgccgaaac cgccgccgct ctggtctccg ctcgacaatg
     4141 tggagcggct ggcgttgatc gacgtgccga acggaatggc tgaggtgccg gcgggcccgt
     4201 ttctgatggg aagcgacccg aagtttgatc gggccgcagg accgcaggaa ctcccccagc
     4261 accaagtcta tgtggatgca ttcagcatcg accggtacga agtcagcaac gtgaactatc
     4321 tgcggtacgt gttggcgacc ggtgcggcct ggccgcacta ctggcgggag cagccattcc
     4381 ccgagaagat ggccaaacat ccggtgatcg gtgtctcctg gcgggaagcc gatgcctatt
     4441 gccggtggcg tggggctcgg ctcccgactg aagccgaatg ggagaaggct gcgcgcggtg
     4501 aagacggccg catgtttccc tggggcaacg agccggccgg gtggatcaag agcaacatcg
     4561 ctcacccggg gtccaagcgg ggggcgaagt atccgccact ggccaatgtc gatcgctacg
     4621 acaatggtgt gagtccctac ggcgtgcatc aattagccgg caatgtgagt gaatgggttt
     4681 cagactggtt cgatccggaa tattaccggc gacaggaaaa tcgcaatccc cagggacccg
     4741 catccggcca ggataaagtg ttccgcggag gatcgtggaa tgaggatccc gaggtggccc
     4801 gttccgccgg acgcaattcc ggagggctgg accactggag ctatctgaca gggtttcgtt
     4861 gtgcaacatc gggcgagagt ggtcgtcagc tttcgtctat cgatccggct atgggacgca
     4921 atacggatcg gtaattgtga cggcaggaca atgaggaggc catagatgaa acgactgcag
     4981 aaagggaaaa ggaaacgaac acgattggcg caggccctcg tgattggcgc cgcgctcttt
     5041 gcgctggctc cgattgcgcg ggcgttggat acgcaggaca tcgtggtgga gtggaccgaa
     5101 gaagggaaaa agatcgcgca ggagcgggtg gcgaattgga aaaccaaaga cgaaatggtc
     5161 ctggttccgg ccggtgagtt cctcatgggg agcgataaga agacagatcg tctcgcttac
     5221 cgcagcgaga ttccccaacg gtcggtctac ttagatgcat tcatgatcgg caagtacgaa
     5281 gtcaccgcac tggagtatct caagtttgtc ctcgccacgg accgtttgcc gcagttggac
     5341 tggcgctacg acggaggcaa tttccaggat acgatggcgc atcatccgat catgcatgtg
     5401 agctggtacg acgcagacgc ctattgcaaa tgggcaggca agcggttgcc gaccgaagct
     5461 gaatgggaga aagcggcacg cggcgtggat ggccgactgt ttccatgggg cagtgagtat
     5521 gccggtccga ccagggccaa cttcggcaga accggattgt ccggcccagt gcgggatcgc
     5581 cccgaacggt tgctgctgta tcccccgatc atttccgtcg acaagtacga gaatgcgctg
     5641 agcccctacg gactgtatca aaccatcggc aatgtggccg aatgggtttc cgattggtac
     5701 gaccaggatt attacaagac tgcaccggct cggaatccga aaggcccgga gaccggcacg
     5761 cagaaagcgt tccgtggtgg cgggtggatg gatagcacca ccaccatgcg agcggccatg
     5821 cggaacggta ccgatccgaa gactaagatc aactggatgg gattccgctg cgctcaggat
     5881 gccaaggaag acacgggaac caaggtttcg atgacgaagg agtaacaggg gaaagggcgg
     5941 tgagaacgta gtgcttgccg ccacaatctc tgagccggtc gtcttctgga tggggagacg
     6001 accggcctcc cttccctccg gttgcgctat gcggtcgcgt cggcgcactc atcatcgcgc
     6061 gcaaatgaaa aaatggagcc taccgaagag ggtaatcaat ccgcctctaa gccccgagat
     6121 caccaacaag ctcaccggca attacgcagc ccgtcgatat cgcctgccac tctcagcagc
     6181 atgtccagca agggagtatt gacctgcagt gcgagctata cgggagaccg atctccactc
     6241 gccaggataa gtagtcatgc gcagactcct cttgacggtc gatgacagat tgcgttattt
     6301 cctacgctga attcgtggtg aaagacggtg ctcaccttgt tgcgagtcat cttcgagagc
     6361 agggtgtgga agtggtaaca ggaatcagcc gatcgtgaaa cggaagccct gcctcatcga
     6421 acattgtgac acctgcgggc ttcgcgagaa ggtcgttctg tgcgacattt cagggagcga
     6481 tctccaagag tttcagaaaa tcaaacgcac gctcgagtac gctcctcatc agactgtgtt
     6541 ttacgaaggg catctgtgcc tgggcctcta cttgctctgc tcgggcaagg tcaagcttac
     6601 gcgttcctcg acccgaggcc ggagacagat cgtccgcatc ctgggcccgg gggagctgat
     6661 cgagaaacac gtattcggcg atcgggccct tcatgaagtg acgtgcgaaa cattggaacc
     6721 ttctcaagtg tgcgtcatcg ataaggaacg ctacctcgcc gtcatccaca gaaatcctca
     6781 actggcaatc aagctgatcc agctcctcag taacgaagtc ggggtcaata tggatcatct
     6841 cgatcaattc acattcaaaa ccgcccgtga gcgcctagcc ggcttgctcc tggagctcgg
     6901 cgaccgattc ggcaaaaaaa agacgatcaa gttcgagtcg gtctcaccct caagcgtgaa
     6961 gaagtagctg agatggccgg cattacggtc gaaaccacca tccggttgct cggcgtgttt
     7021 cgcgacgagg gagtcctcac cattgatggg cgaaccatca ccttgctgaa tccagaccgc
     7081 ctctccagaa ttgccgagcg ctgatcaccc cctttcccgt tgcgtgaccc attgttcgtg
     7141 aagcgcgtcg gggcgacgcg acgttcaagt ttgcagtgct gacagcccac acacaactcg
     7201 gctctcccct cattgcactc atcagcttct cgtctctcac gcatcgcctc ctgcaggcat
     7261 aggtctaatg gcctatccaa aaccttgaga taaatcatgc ttccgaccgg ctgatgccag
     7321 tgtggcctgg ttacctgttc ggtacagtgc gcagggcatg acgctgtcgt atggctcgca
     7381 gattggagct tccgtccatg ggattccgga acgatggtgc ctcaaggtag caggcgaacg
     7441 agtctcctcg tcgatccttt ggcgctgctc aagcgggagc atcacatgat tctggagcga
     7501 ctggcaatga tcgagacggc gatgagtccc tgctgctccg gcagcggagc ggtgaagcag
     7561 acgaatcgtg acacgctacg ggacctgctc gaatttttta ccggcccggt ggatgtgcat
     7621 ttcaagcggg aggaaatgct ggtggacaat ctccggagaa ctctgggccg gaatcgggaa
     7681 gaaaaagagc agtttcagag cttcgtggaa gaacaccagg ccctgaaaga tgatgcgaca
     7741 gcggtgatgc aacagttggc gagaaagcgg agcgacggcc aagacggagt ggagccaaag
     7801 gcctgcggag ggttgcgagc gctgaccgat gagcttcacc ggctgattcg tcgctatcgt
     7861 gagcagattg cctgcgaaga gcggctgctg ttcgccttgg ccgagatgcg gttgaccgcc
     7921 gaccagagac gtcgaatcag ccaacggatg ttgcaagtgt gaactcgtgc atcagcggca
     7981 acaggcgtgg gaccgatgag gcgcgtgact ggctggtgtg aggccggcac gaggggcact
     8041 gaggtgttgg atgagcgacg gaggaagaag acggggaatc gccgcgatgt tcagaagggt
     8101 gaatcacatg cttgcgctgc tcctgtctcg ggccggttgg ggaaagacgg ggagccaacc
     8161 cgggcgccgg tcaggcgcgt cggtgacaca tcaaggaggg gattatgaag cgggtccgga
     8221 aagtcgtgca gaacattgga atgtggggtg cgggggttgc gatcgccgcg gtgctcggtg
     8281 ttgctggtgt gcagccggca tcggctgaag aaggcacggg caacatggtg ttcttcaagg
     8341 gcggatttat gaatttgaac caggatcgca gcgggcagat ttttacggat acggcaggca
     8401 tcgccggcgc caatggaggc aacgccggat ggtatgcggg ggcggggctg gatctggtca
     8461 tgtcgaagga tgtctggggc ggaatggaca agacgtgggt gctcggtgaa atcgggctgc
     8521 aatttaacag cattaattcc tcccgcgtga ataatgccgc cgggagcatt gcgaccagaa
     8581 cgttaactga cacgctggcg acggatccgc agaaagtgca gctcacgatg gtgacgatcg
     8641 acgtcgctcc gaaaatcaag tttatggaag gcagcgcgtt caggccatgg gtcattccgg
     8701 tcggtctgga tattcatgtc atcagccctc cgtcgaatcg cacgcagtac ctcgacctgg
     8761 gcgtgcagtt cggtgccggt tttgagtatg cggtctggaa ggcgttcaaa gtcggggttg
     8821 atgcccggta ccacctgacg gcacgtctga ccaacaccaa caacgattac ttccaggttg
     8881 gtccctatgt cgggatttcg ttctaagcac gcgagaggtg aggcgtctta gtgtaggatc
     8941 ggaacatcag tcgtaagcca atgagaatga cggtgccaca ccggccgttg ccgaaagcag
     9001 gccggtgtgg catcattccg aatcgagatc tccggaggcc gcgcgttggt ggatatcacg
     9061 ctgtatcttc ccgacgattc ttccttgccg tttccgattg gcgaacattc tccacagcag
     9121 gcctttgcgc atcgcatcga ggaaaccggt tccgggctcc atcatgtggt gaccttcacc
     9181 ggtcttcccg aacacatcga tctggcgttg caggcgatcg gtgaatccgt ccgtattccc
     9241 ggagcgtggg cggcagttgg ggggcaacgg atgtccagcc tcgtcgcctt gtggaatcgg
     9301 ctcgactgtt acaggcagag tctgtcatgt tccgatcggg tgagctactg caggaacaaa
     9361 gccgcgagtg ttcgagtcgg gttgggctgc gggctggcgt tctgctcggc gccgtgccag
     9421 tttttgtgcc cgctctgcag cttgaaagac actcctcttg cacagtccat tgtgcacccc
     9481 gaaacgcagg tcttggtcgt tttgggagaa attgattggt gcccgaatct cgctcgtcct
     9541 gccgaccggt agtgtggccc gccttgcgtc cccgttcatc cctctgtcat ggtgccgttg
     9601 aggcatagcg gaaaaaggag gccctgtgtt tgcattggtg tggattcacc tcttagcggc
     9661 tgtcgtgtgg gttggcggga tggtgttcct ctccgtcgtg ttggtccccg tgctcaaacg
     9721 ggacgggggt tttgcgcgcc acgccgcact cttccgaacg gctgcctatc gattcagagc
     9781 gctggtgtgg ggcgccatgg gaattttggt cgccaccggg tcggtgctag ctgcagggcg
     9841 agccattcct ttgagtgatc cgtcgcaatg gccgtctatt tttatgacga agatcggact
     9901 cgtcgccttc ttgttcacgc tcacactgtt gcacgatctg gtcgtggggc cacaggtgcg
     9961 gcgcattctc ggaaccgcag aggcagcgag gagtgcaaag gatcggttgt tagtgcggta
    10021 ctccgtgctg gtaccgcgcg tgtcgctgct ggtggcgttg ctggtactat tggcggctgt
    10081 ggtgttggcc cggacctagc ctcgttcatt gaagaatgat cgaggcaacg tacgatcgat
    10141 ggtcgagacg gcgtctcgta cgggcacgct tcggggaaag tcttatcgtg tcgcgggagt
    10201 tgtggagggc cggagtgcgt caaccagacg ttcggtttgc gcgtggctcg agagggccaa
    10261 tttcatcacc accccgcata acgcgaatac gaccgcgttc agcaggaaaa agacgagcgc
    10321 cagtgaaccg gtcgtgagtg cccaggcttc ggagtctgcg cgattgcgcg ctaacacccg
    10381 tgcctcctcg tcacggatct gctccgtgat gtcatggatc gtgtccatcg tccgattcag
    10441 ttgattctga gtcacgatgg atttggctcc cggtagtccc ttagtcctcc ggagggcaat
    10501 ggcctgttcc atttcgtccg accgctggtc gacttgtgtg gcaagatagg ccacccgatc
    10561 ctgctgcaag ttattgtccc tcgtcaggct gccgatccgt cggatctgtt cctggagcat
    10621 gtcgagcgct tctcgatacg gtgccagata gttatccgac ccggtaatca ggtaaccgcg
    10681 ctgatgggtt tccgcccccg acacaatact ccgtacacgt tcgagttcaa ttaagacctg
    10741 ttcatttcgg gttgcccaat tgtttgaggt tttgaagtgc atcaggctga ggaaacaggc
    10801 ggccacgatg gactcgactg caagaaatcc cacaatcagg gcaatgatca ggcctttgcc
    10861 ggcgaggatt cgacgaagcc acgtcagatg ggtctcgtac aagatcatcc tatagcacta
    10921 cccacccctg ccccctgatg tcaacccgac aaatcccttg gtcgggtcgg cgatgtgtca
    10981 aaagtgtgtc gtcgcagaac agtgggtagc agacctgcgc ttgaagatga atcgctccag
    11041 tcccgtcaca actatcagcc ggtggatgaa tccattttgt gcttcgtgcc tctcaatcat
    11101 tgatcgcagg cataacctgt gcaaagtcag ggcattggtg aaggccgtac gcatggcggc
    11161 tctggcgtct aaagcccaag cgcaagtctc agcggcggtc cacttttacg gaggtgcatc
    11221 atggcgagag tggtcatcat cggggcatcc atcggggggt taccagcggc ctacgaagca
    11281 cgagaattgt tggcgaagaa acacaaggtg acggtgattt ccaatgtgga atcctttcac
    11341 tttgtgccat caaatccttg ggtcgcggtc gggtggcgta cccggaagga cattagtttc
    11401 gccttgggtc cggtgttgga gaaaaaaggg gtggagtata tccacgcgac agcggaccgg
    11461 atcgagcccg agcaaaaccg ggtcatcacg tcgaaaggcg aagtcccgta cgattacctc
    11521 atcatcgcga ccgggccgaa gctcaatttc ggcgcggtgc ccgggctggg gccaagcggc
    11581 tatacgcagt cggtctgcaa cgtggaccat gccgaacagg cctggggcac gtatcaggca
    11641 tttctcaaag acccaggtcc tatcgttgtt ggagcggcgc aaggggcatc ctgtttcggc
    11701 cccgcctatg aaatggcctt tattctcgat gccgaccttc gcaagaagaa actccggaag
    11761 aaagttccga tctatttcgt gacgccggag ccctatatcg gccacatggg cctcgcgggg
    11821 gtcggcgcgt cccgccggtt gatggaagat gaatttgccg agcacgcgat gaagccgatg
    11881 tgtaatacgt cgatcaaaga ggtgcagccg gggaagatgg tgctggaggg cgggcaggag
    11941 attccgttcc gctactcgat gatcattcca ccctttgccg gcgtcgacgc ggtcgcggga
    12001 acgccggggc tgtgcaatcc gaaagggttt gtgaatatcg atgcctatca ggcgaatccc
    12061 aagtataaaa atatctattc cgtcggggtc tgtgtggcca ttcccccggt ggaacagacg
    12121 cctattccga ccggcgcgcc caagaccggg tacatgatcg agtcgatggt gtcggcggcc
    12181 gtgcataaca tcaaggccga tatcgacaac gacacaaaac gtgaaacggc gacgtggaat
    12241 gccatctgcc tggccgatat gggtgacacc ggtgtggcgt ttgtcgcctt gccgcaaatg
    12301 gcgccgcgca atgtgacttg ggcgaagaag ggcaagtggg ttcatttggc gaaaatcgcc
    12361 ctggaaaaat actttttgcg caaaatgaaa aaaggcgtga gcgaacccta ttacgaaaag
    12421 gtcatcctta aagcgatggg tattgcgaag ctggaagagc cggcatgaag ggaaaccggt
    12481 agagtcgtat gatcgagcag gcgttgcgcg cggtggtgtc cggggtgcct atcggcctgc
    12541 aattgggtgc gaccggaacc ggcggcgcga ttctcggggt gccgctgatg gtgtatatcg
    12601 ccggcatgtc cctgcagcag gcggcggcca tgtcgttgat gattgtcggg gcgtcttcct
    12661 tggtaggcgc gtgggaatat ggccggcaag ggatggtcaa accgaaagcc gccgcggcat
    12721 tcagttggac aggcatgatc ggttcgtggg gcggcgcgtt cgtccatcac atgatccgac
    12781 aggaaatatt gctggtgctg ttcggcctgc tgttgctgct ggtcagaacc gtcatggcgc
    12841 gccagcggga actggcggct gagcatggag cggatgaaag ttgtgccacg ctgttcccgc
    12901 gcacctgctg gatgaaggtg gggggaatcg ggttgatggt ggggacgctg aatggattgt
    12961 tcggggtcgg cggcggcttc atggtcgtcc cggccttgat tctggtgttg ggttttcctg
    13021 cccgtgcggc gatcggcacg tcactcatga tcatttttat gatctccatc ggcggcgtgg
    13081 tgggacatat gcagttcggt catgtcgagt ggagcctgtt aggctacgtg ctgctcggca
    13141 gcgtgaccgg catggtactg ggtgttcgcg cggatacctg ggtgtcccct gtggtgatgc
    13201 gtcgagtgac cgcctcgatc accatctcca tcgcaggcat attgatcgtg gtcaacctgg
    13261 cgaagcttgc cgggtggcta ggctgaactc tattgacagg tcgcggattc tgtcggactc
    13321 tcagaggaag gtgctcgtgg atgttgttcc gggcatgagg tgcgggtgcc gggggaacgc
    13381 attccgttca aggcttacat gggctctaca ttcggatgat gccgtatcag cgtgtccttg
    13441 tgtccgtcgc attccgtgtc gcgttatgga ccgtggcagg atattccatg gtcacaccgg
    13501 agcggacggc gcaagccgaa tggtcggcga tcgccgagca aaaaaccagc tatacaaccg
    13561 atgcgtttca attttcttcc gcgcgccggc tccgattgac ggaagatcct tctctgccca
    13621 cggtcgtctc gaccgacaaa cctcaagatg tgatctggga gcccgctctg gaagttatcc
    13681 attccacgcc gacgatgcag gggaaaaacg aattgtcggt gaaggcgcaa ggggcgattt
    13741 acaccaacaa tcccattttc aaccattccg actttcgcat tcaggatcgc ttttcgctcg
    13801 accaggcgac gtcggtgctc gttcgctacc gatacatccc caatctcttt cttggcccca
    13861 acttcgagcg ccgaaccggc acacgctcgg ttcaggaaga acgggtcagt tcgcatcatt
    13921 ggcgcgccga ggtcgaacgc cgcttgtccg acacggtcac cgcgaccctc atcacccgct
    13981 tcgggatccg gcgctacaac gatgtgtttg cggaacgcga tacgaacctc tggacggtcg
    14041 gctcgcgtgt ggactatcgc gcgaaggaat ggctgacgct cacgctgtcg tatctgtacg
    14101 aacgaggtct ggcggatggc cacaaggaga ctcaatttgc cgatgacgtg tcctactatc
    14161 tccacatggt ctcggccggt acggagttcc ggttgcacaa ggaatgggat ctcggcttga
    14221 cctatatcca tcgccggaaa acattcacca gcggtattgc gggcgacagc catgtcgatc
    14281 ggtttgacgc cacgcaccag gggattgcgg agctgcgata ccacatctcg acggctgcga
    14341 cggctatgtt gtcgtttcag tatggcaaac gtacctcgac caatgtcctg agagactttc
    14401 aggattcgat tgtctcgatc ggtggtcaat accggttttg atgccgaccg ggtggcatgg
    14461 ttgccgctct cggaggctaa gtgactgaat acacaatgaa ctgccgttga atcctttcat
    14521 cgtccggata ctcatacgga atgagaaagg aggcggatta tgaagttgaa cgaaatgctt
    14581 cggttgatcg ctggtgtgtt cgtgttgatc gcggtggtgt tgggtgcaac ggttcatccc
    14641 tactataatt atttcgcggc gtttgtcgcg gcgaatctca tccagtcgtc attcaccggc
    14701 tggtgtccga tgatggctct tttgcggagg cttggtgttc acgagtaacg acacacgttt
    14761 cagcattgga ggccttgtgc tcgccctgct cctggcggcc ggctgcgggc cttctcagga
    14821 acccggcaag ccggggaaca tgaccccggg tactgcggga caggagccga tccaggtgcc
    14881 ggtgatcgag gtcgcagcca gccaggtccc gatctcagtc gaggtgacag ggcaggtaac
    14941 agcggtctat caggcgacgt tggccagccg gatccaggga atgatcgata acctgctggt
    15001 ccgcgaaggg agcgtcgtgc gtcagggaca gactctggtg gtgctcgaca accgggacgt
    15061 gcaggcggag ttgtccagag tgacggcgga actcgacaat gcgaaggcgc atcaagaccg
    15121 gatggaagag ctgtatcgca aagatgcggt atcgaaacag gaattggaga atgcgacgcg
    15181 tgccctcaga gtggctgaag ccggccgcaa ggcggtgttg gcgcaattga gttacaccat
    15241 cgtcaaagcg ccgttcgacg gtgtgatcac cgaaaaaaag gtggagcgcg gggaattggc
    15301 ctccccgggg caaccgctcc tgaagatgga agatcccggg cggcttcggt tggaagccac
    15361 cgtagccgaa agtgatgtgc gggtcgtgtc agtcggctcg ttgctgcccg tcgtgatcga
    15421 cgccttgggg gcgaatccgc tcaaaggcac cgtgtctcag attctccctg ccggtgatcc
    15481 gcaaacccac accttcacga ttaaagtcga tttgccacag gcaggcggcc tgaagtccgg
    15541 catgttcggg cgactcaaac ttgagaaggg gatgagtacg acgctgctcc tgccgaaatc
    15601 ggcgttgatc gaacggggtg aactggccag tctgttcgtt gtcggaggag accagacggc
    15661 tcgccttcga tgggtcagga tcggccgcac gttggaacaa ggggtcgaag ttttgtccgg
    15721 tgtcgatgcc ggagagcggg tcatcgctga cggaagcaaa ggtcgcgacg gcgcgctcgt
    15781 gcaggatatg accgcggtgg ccttgccgcc ccaggcgcgg taatgctgtc gacagggcgg
    15841 tctggtacac agcacaacgg atcttgtctg gatgtccatg atggttcacg aatgacgacc
    15901 ccacgcctcg gcgccagcgg acgtctcgcc gcactcttcg tcggcagcaa actgaccccg
    15961 ttgatcatcc tcgccagcct tctcctcggc ctgttcgcgg tactgttgac gcctcgcgaa
    16021 gaagaacctc agatcgtggt gcccatggcc gatgtctggc tcccattccc cggggcctcc
    16081 gcgaaggtcg ttgaagagca ggtcaccaaa cccatcgaac gcaagctctc cgaaatcaaa
    16141 acggtcgaat atctctattc gatttcccga cccggcggcg cgctcatcat cgtgcggttt
    16201 tatgtcggtg aaccgatgga gcagagcctg gtggacctct atgacaaatt gatgtccaac
    16261 caggatctgt tgccgcctgg cgccgcgccg tttcaagtca aaccgcgtga cgtcaatgat
    16321 gtgcccattg tcaccctgac gctgtcgagc gagcgctata cggatttcca gctgcgtcag
    16381 ttgggcgacc aggtgctgga ggatgcgaag aaggtgcctg gcacggcgag tggtttcgtg
    16441 gtcggtggcc gaggtcgcga gctgcgcgtc cagattgatc cgacacggtt gaaagcctat
    16501 ggattgacac ccttgcgagt cgccagcgtc attcaggggg agaatttagc gctgcctgcc
    16561 ggccggtttg agagccgaaa cgaaagcttc ctggttgaga cgggccggtt catccgctcg
    16621 aaggacgatc ttgacggcgt cgtggtcggt gtcaatgaac aacggccggt ctatcttcgt
    16681 caggtggcgg aggtggtcga tggtccgagc gaaaccaatc agtacgtatg gttcggcgaa
    16741 ggggcgcgaa gcagttcttc ctcttcgggt gaaacaccag ctgtgacggt agcgattgcc
    16801 aaacaagccg gcaccaatgc ggtgaccgtc gcgcagggag tgattcgaaa agtcgaggaa
    16861 atgaaggggc gattgattcc agccgacgtg caggtgaccg tgacgcgcga ctatggagaa
    16921 accgccgatg agaaagccaa cgaactgctc tggcacctgt tggtcgccgt ggttgcggtg
    16981 gtggtctttc tcgggctgac gctgggattc cggccggcat tcgtcgtctc cattgccatt
    17041 cccttgaccc tggcactgac gctgttcatt tccatgctga tcgggtacag catcaaccgc
    17101 gtcacgttgt ttgccttgat cttttccatc ggcattctgg tggatgacgc gatcgtcgtg
    17161 gtggagaata cctatcggca tctcacactc cgtctcctcc cgcatcgcga ggcctcgctc
    17221 tttgcggtcg acgaagtcgg caatccgaca attttagcga ccatgacggt tattgccgct
    17281 ctcctgccga tggccttcgt gtcggggctg atggggccgt atatgcgtcc cattcccgtg
    17341 aacgcctcga ttgcgatgtt tgtgtcgctc ctggtcgcat tcatcgtcat cccctggttc
    17401 tgtcagacgt gttatcgacc gggcgtacac atggcgggcg tcgatcatga ttcgtttgag
    17461 gagggtcgca gttatcgact ctatcgccgg ttgctggctc cggtgttgtc gcatccggtg
    17521 atggcttatc tggtgatagg cgtcattggg ctgttgttgg ccgggtcggt cctgttgttc
    17581 tggacgcgcg acgtggtggt caaaatgctg ccgttcgaca acaagagcga attgcagctg
    17641 gtcatcgata tgccggaagg cacgacgctt gaggaaacgg cccgggcgac caaggccctg
    17701 acgcaatatg tgcgaaccat tcccgaaatg cgggattacc aggcctatgt cggtacggcc
    17761 tcaccgttta acttcaacgg gttggtccga cactattatc tgcgcgagca gccccacgag
    17821 gccgatatac agatcaatct cgtggcgaag gatcgacggc aggcacagag ccacgacatt
    17881 gcccaacgga ttcgcccgcc ggtgcaggac atcgggcggc tctatggggc gaatgtgaaa
    17941 gtggtcgaag tgccgcctgg tccaccggtg caatcggtcc tcgtcgctga gatttatggc
    18001 cctgaatacg accgccagat cgagatcgcc agggacgtgc gccggatgtt tgaaaccacg
    18061 gccggtgtcg tcgatgtcga cgactacttg gaagcggagc aggtcaagta cgtgttttcg
    18121 gtcgaccgtg ccaaggcggc cttggcgggc attccgtcag aggaaattgt gcggaccctc
    18181 cgcctcgcac tggaaggtgc cgacgtcggc ctggtgcata tcccgaaaga gcggcgaccg
    18241 gtgcaggtca aacttcgcct gccgatcatt gagcgaaccg gcctggaaca tctcggagaa
    18301 atcgccctgc gaacgaccgc gggtcatatg gtgccgcttt ccgaactcat ccgcgttgaa
    18361 cagaccgtcc gtgaacaggc gatctaccat aaaaatcaga agccggtcgt ctacgttatc
    18421 gcggatgtcg gtggcacagg ccccgacaag ggcgagagcc ctgtctatgg cgtgatgggt
    18481 atcggcaaga aattggaaca gtacaggctg ccggaagggt atcgattgga acaacagtat
    18541 gccgtgcagc cctggtcgga acagcggttc gccatgaagt gggacggcga gtggcacatt
    18601 acctatgaaa cgtttcggga tatgggtctc gccttcgcgg cggcgctcgt gctgatttat
    18661 ctgctgatcg tggcgcagtt tcagtcgttc ctgacgccgg tggtcatcat ggcgcctatc
    18721 ccgctgacct tgatcggcat tcttccaggc cactggctca ctggatccta tttcacggcg
    18781 acctccatga tcggatttat cgcgctcgcc ggcatcatcg tgcggaactc gattctcctg
    18841 gtggatttca ttcagcatca ggaagccgaa ggcatcgcgc tgttggaggc cgtcattcgc
    18901 gcaggagcga ttcgtacccg tccgattctg ctgaccgcgg cggcgctgat ggtcggtgcc
    18961 ttcgtcatta ttctcgatcc gatctttcaa ggcctggcgg tgtcactgct gttcggggtt
    19021 ggtgcatcga cagtgttgac cctgattgtc atcccggtgc tgtactacct gtggatcggc
    19081 gagcgccgac ctgtctctgc ctgtcccttg cctcaagctg ataacccggc agcgccacga
    19141 catgccgtgg gcaatcagcc tggctgaacc gttcctggaa tatctctcct tccctgcaat
    19201 cgatccgctc ctattccaca agacccttct tgaagtccta cgtacaccgc tccccaggaa
    19261 aaaagcttct caatcggcga gcggggaaac tatactgtgg ccccacgcgg cacgccgttg
    19321 tgccgcaaga tctgtgatgg atggaatctc tcgtcatgtc gcgaagtggt gagcatgtgt
    19381 caatgggcag tgtaggtcac gagcaggaag cgccgctgct ctcctggtgt gaggcggata
    19441 cgcgtcggta tgtccagatg ctggtactgg ctcttgtgag cgggtgggcc tattttgcca
    19501 atctgcacct ctcgttattg gaaggcagcg aagggttgta tgcgggtatc gccggagaga
    19561 tggccaggcg gggcgagttt ttcgacctca cctatcaagg cattccctac ttcaacaagc
    19621 cgccgctgtt tttttggttg ctgaacctct cgacgtcgat ctggggagat cacgaaatcg
    19681 cgttgcgcct gcccggttca ttggccgcgg tgggtacgat cctgctgacc tatgtgctcg
    19741 ggactcagtt gatgtcgtcc cgggccgggt tctgggccgc gctggttgta gccaccagcc
    19801 acgtctttct ctggtatggc cgccgcgtat tattcgattc gacattgacg tttctggtca
    19861 ccctcgccct tttcgcctgg attcaggttc agatcctggg ccggagctca cggtggtatc
    19921 tggtgacctt cctgagtatg gcgctgggag ccatgctcaa ggagatgcac ggattttttc
    19981 ttcctcttct catcatggcc ctgtatgcgg tgattcagcg cgacgcccgc atggtacgcg
    20041 acagattctt ctggatcgga ctggcagggg ccattgcgtt gctggcctgg tattcgcaac
    20101 tgttgagcgt cgggtatcag catcattttc ttcttgggag tgcgatcaaa tccgtgtgga
    20161 atagtggctt gtcgggtgcc gccgggacgt ccaaagacgg gcatcctctc tattggtacc
    20221 tgggcatgat gtgggcggat tttttcccct ggtgcgcgct gctgccgtcc gccctcctgt
    20281 tgttgtggca gcaacgaccg ttgcgcgcgc atcagacgga actggtcttg ctggtgtggg
    20341 tgctgggcct cttcacggca ttcagcctgg ccacgctcaa acgtgagccc tatctgacga
    20401 ccgtcgttcc cggcatcgga ctgatgatcg ggtatttcta tcatcggtcc agccaatcgt
    20461 cggatggctc acgaaccatg tcgccggtgt tgagactgtt tctggtggtc ctggccctgg
    20521 tgtttatcgg aggcatgttc ttcggcgccg cgccgttgcg ccgccgttgg ctggtctccg
    20581 ctccggtcgt gtctccgctg ttcatcgtga ttatggtttc cctgggcggg gcgctcttgt
    20641 atgccgcgat caccagccgc cttcagctcg ccttgcgtat ggtcggcgtg cttgccgtgg
    20701 cctatgtagt cctggtggtg aactatgtgt ttcctgcgat tgatgaggcc gcttcgccgc
    20761 gcaaagctac cgagtacatc aaatccgtgg cgaaggaagc aggaccgccc atgttcctct
    20821 tcattcccgg ttggcccaaa aatgaagatg ccgtgtatta cttgaagcgg gacacagtcg
    20881 tgcgcgatct tcccgatgag gacgccgtac atcacgccgt gcgaacacag gggcccatcc
    20941 gggtcattac cgaggaatcg catatggtca ctctccagaa gcaggccggg ttggtcgtcg
    21001 aaacccttca ggagttcctg caaccaggcc gcaagcatct gtatctgctg tccatccaac
    21061 ctaaaggctg aggtcggttc tgctctgcgc ctctgtcgca ttctgccaca gaggcgcaga
    21121 ctctctctgt agcagacctc cccgattctg acgtcgtttc ccgatcattc cgtccagtcc
    21181 tgctacgtag gagaagcgct tggctttgct cgtatcagac tcagagcagg gcgccatcct
    21241 tgcacttctt cccttcgggg gcggtctgcc tatgtgaaac cgcaagccca ttaccgcatc
    21301 gcggtggagc gagatggtcc cgtgcacagc tcgtcctgaa gttgatgcgg gaggcgcagg
    21361 tcggttctgt cacgaatgga ggaggggcat gcatccgatt catccgatgg tcgttcactt
    21421 tcctatcgcc ctcttgctgg caagcttgtt gttcgatctg gtcgccctgc gatggcgtgg
    21481 ggaagaattt cgtgcgacga gtttgtcttt gctggcgctc ggggtcctcg cggcgttggt
    21541 agccttgctc accggtcatc tcgcggaaga ggccgtggag catagcggga cgattcccaa
    21601 gcaggcgatc gaaacgcatg aggaactcgc attcgtcgtg ttttggctgt ttgccggcct
    21661 gctgggtgtg aaaatgttgt cctattgggg ctggatgcga gaacgttctc tcctcgtcct
    21721 gttcctgggt gtgggtgggt cggtgttatt gcttgtcgcc agttactatg gcggcgaatt
    21781 ggtgtatcgc tacggcgcag gggtcttgcc tcgatgaaga tgatcggcgc cctcactcgc
    21841 atggtcgtag cgatggccgt gattttcggc gcggcgcccg tttctgccga gaagtccgat
    21901 ggccgttcac cactgggcga gcgggcggtg ttgcgagcgg gtcaggtggt gcagggtgat
    21961 tattttgcgt ttggtccgca ggtcgaaatc tcgggcatcg tgaatgggga tctgtacgcg
    22021 gctggcggtg aagtgattgt ggatggcgtc gtgaacggcg atgtgatcgt ggcgggagcc
    22081 aaggtcgtgt tgtccggcac tatcgcccag gatgcccgcg tggctggcgc gcacgtcacc
    22141 gtgagcggga cgattgggag aaacgccacc cttgccggtg ccgatgtcca tctgacggag
    22201 aaggcgactg tgcgtgagaa cgtcattgca ggcggcggct ccgtgcagct gtcgggagcc
    22261 atcggccgcg atgcacgggt cggcgcatgg catgcgacct tctccaatga gatcaatcgc
    22321 gatgtcattg tggcggctga atcggtacgt ctgacatcca aggcctcagt gggcggacgg
    22381 ctgcgatatt ggggtgaggt agcgccctcg atcgacgagg aagccgtggt gcatgggccg
    22441 atcacacgtc gccccttgcc ggaggggtgg agcaccgagc gggcccgcca ggggctggtc
    22501 gggatgcgag tcttcgcggc catcgccagc tttctatcga cgttgctgct gggactgatc
    22561 atgctgcgtg tatggccgca attggtccga caggtcaccg gggcgatacg cgaacgaccc
    22621 gcgccctctg tgggatgggg gcttgccgcc ttaatcgtca cgccgctggt tgcgatcagt
    22681 ttcgtggtga cgctggtggt gttgccggca ggggtgatgc ttctcgcgtt gtacggcgtg
    22741 gcggcgtatc tggcaagaat ttttgccatc acctacgcag ggcaattgtt tgttcgccgc
    22801 caggacgatt cctcctcact tgcccggccc tttgtcgtcg ggctgctcgt ctattcactc
    22861 ctgacactcg ttccggtcat tggaggtctg gtgactttgt tcaccgtgat ggctggattc
    22921 ggcgggttgc tcgtcgccgt aaagcaacgt ctcgcagtga gacaggaaca ggacctggtg
    22981 caagacaccg cctgacgcag actatgaatc gcccttacac aatggcgccg cgggggcaat
    23041 cggctgccgt caccttcctt gacggtcgaa cactgcgttg tcttggctcc tggacgatgt
    23101 ccgatgtcgg accggccgaa cgggccctca gggtgatgga ttggccggct gatggttcgt
    23161 tgcaatttga gggaagcggg atacacgctc tcgatacggg cggcgcagtg gtcctgtccc
    23221 gggcagtcag ggacgctcag cggcgcggct gtgacgtcac ggtcgaagga ctgcgctctg
    23281 aacatgcgca gctcatgaac ctggtgtcgg ttcattggga cgccatgatg gcgcatgtgg
    23341 cggcgcgacc gaagggcacg gcgcgtctcc aatccgttat tagaaatctc ctcgaccggt
    23401 tcctgcgcgg cttggggttt atcggcgaga gtgcgatggc gctgctgcgg gtcggctcgt
    23461 cgcccactca cctgcgctgg cgcagcgcct tgaacagcct ccggctcgat ggagtgaatg
    23521 cgctcccgat caccgggttg ctgacatttc tcatcggcgt cgtgatcgcg tatcagggcg
    23581 ccgaacaact gcgaaagttc ggcaccaaca tttttatcgt ggacctcgtg gggatctcac
    23641 tgctgcgtga aatcgccccg ctgatcgccg ccattttgat cgccggacgg tcgggatcgg
    23701 cgtacgcggc acacatcggc accatgaaag tgacggaaga actggacgcg ttgcgcacat
    23761 tcggattgtc gcccaccgag ttgctggtgt tgccccggat gctggcgctg atcgtggccc
    23821 tgccgttgtt gaccgtctat gccgatgtgc tgggtgtgtt cggcgggatg ttgatcgccg
    23881 cgaatcagct caacgtcagc tttacggctt ttctggcgag attcgaggaa gcggtggcct
    23941 tgcggcattt cctcattggc gtcggtaagg cgccgttttt tgccgtcatc attgcgctgg
    24001 tcggatgtta tcagggattc cagattcgag gcggtgtgga cgatgtggga cgacatacca
    24061 cgatgagcgt ggtgcaaagc atctttctgg tcatcatttt tgatgccctg tgcagcatca
    24121 ttctcaattg gtggaacctg tagcccggac cgctcatgaa tacctgctgc ggcatccgat
    24181 accttcgtcc ggcagggcgt ttctcgttcg ccctcctcaa cgtatcgcgg atacgcctgc
    24241 gtcggcctcg cttgcgagac gccctggcgg acttcggtct cggatgcctc gcgacggcat
    24301 tcatgagcaa tccgggctac taagatgttt gaaattcgtt ctccggcccg acctaatctt
    24361 ggggaaatga cagggtctta tgtctctcgc tgcgcacact gagacgccga ttatcgatgt
    24421 gcggcatgtc tcgacgcgat tcgggccgac ggttgtgcat caggatgtga gcctcactgt
    24481 gagaacgggc gaggtattcg cgatcgccgg cggcaatggt tgcgggaaat ccacgctctt
    24541 gcgggaaatc gtcgggctgc tgactccgac ggccggacgt atcagcctgc tgggagctga
    24601 cagccgggac ctccaagaga ccgacggcgg ttccttgtat cgccgcttcg gcgtgatgtt
    24661 ccaacacggt gcattgttca gttccatgac cttggccgaa aacgtggcgg tgcccttacg
    24721 agagcatacg tcgctcagtg cccggctcat ccgggatatc gtggcattaa aaatcgccct
    24781 ggtcggtttg ccgcctgaca gcggcgtcaa atttccccgc gaactcagcg ggggcatgag
    24841 gcggcgcgcc gcattggctc gggccattgt gatggacccg gaactcttgt tcctcgacga
    24901 acccaccgct ggcttggatc cgatgatcgc cgccggcttt gacgatctgg tgcttgatct
    24961 gaagcgattg ttggggctca ccgtcgtgat ggtgacccat gacctggatt cgttgtggcg
    25021 catcgcggat cgcgtggtgg tgctggggga agggcatgtc ctgggcatgg ggaccatgga
    25081 acagctggcg gcgtcggagg atccagccgt ccggaattat tttcatgggc cgcgcgggcg
    25141 cgccgtacag ctgaatcaca gcgggggaga gtcgcatcgc gattgagagg taacgaatgg
    25201 aaccgaaggt caactacgtc gtggtcggcg cattcgtcct cctgctgggc gccacagtgc
    25261 tcggtgcggt gctctggctg ggcaaaaccg attaccgcgg catctacgat cgctattatg
    25321 tctacaccag ggaatctgtc gccggattga gcgtcgattc gaccgtcaaa taccgcggtg
    25381 tggatgtcgg gcgagtgaag gaggtcattc tcaacccgga caattccgag gaggtccgcg
    25441 tgacgctgga catcgtcgga gggacaccgg tcaaaacgga tacgcaggcg gtgttggtca
    25501 cacaaggact cacgggactc gtgacactga acctgacggg aggaagcaaa gacgcgccgc
    25561 cgttgacgtc cgtggcaggg caggtgtatc cggttatcca gagcgttccc tctttgtacg
    25621 gccgcctgga tggaaccttg gccaaactct tgtccgacca gggcctgtcg aatctagtag
    25681 ccaatgtgaa cgggctcgcg cagaatgcgt ctctgttctt ggacgaacag aatcgtgcgc
    25741 agttccggca gatcctgaaa gacctgggag aggtcacgaa ggtgctggcg gccaggagca
    25801 gtcaggtcga ccgcggcgcg cagcatgcgg cagaggcggc cgagcggacc gcgcgcctca
    25861 cggagcacct gggcgtacaa ttgccggcgc tcttggatcg gatgggtaaa agcgcagcgg
    25921 cgctgcagca catgacggca gaggtgacac ggacgagccg tgaagtcggg gatatggtcg
    25981 gtaccagcaa gccgggcatt gaacaatttt cacgacagac gttggcagat gccgggctcc
    26041 tggtaagtga attgcgacaa ctcacggcga cgctgactcg agtggcgcaa caagttgaac
    26101 gtcagccgaa tgttttggtg cttggccgac agggtcagcc gaagggccct ggtgaataga
    26161 ggatgagacg tgctccgtag tcgcgtaacg ggatgggtgg gattggtgct ggcggtatac
    26221 accgccagcg gctgtgtact gccaaggtcg gaggactcgg ctgtccggac gtttgtgttg
    26281 atgcgtgagg agacggatcg gcaagcggcc cctgccgggg caccggccgg catgcacggc
    26341 gtcttggtcg tcgcggtacc gcaagcagcg ccaggattcg agcagccgcg catcgcctat
    26401 ctgcggcggc cgtcggaagt gagctattac gccaatcatg tgtgggccga tagtccctca
    26461 cgcatggtat tgccgttgtt ggttcgatct ctggacacga ccggactctg gcggaccgtg
    26521 gtgccgatgc ccaccggaat caaaggcgat taccagttgg atctgtccgg tctggtcgtg
    26581 cagcaggaat ttctgcagca gcccagccgg agccgggtgc aggtgcgcgc gcacttggtg
    26641 gatgtgaagg cacaacgtgt cctgggtgcc aggaatttcg aagcacttga accggctccg
    26701 agcgaggatg cctatggtgg ggtcttggcc gcagatcgtg cagtggcaac cgtgctcgcc
    26761 acgatgaatg aatggatcgc gtcctgcctg cgaggatcag gtcgcgaaac ctgctgagca
    26821 tgaacgaccg gtgaggagcg aggatgagca gtcgaacatg acatggtcta tggcatgcgc
    26881 accgcgctga aggtcggatt cagtttcgga ctgacgtccg gggtcattac cacgctcggc
    26941 ttgatggtcg gccttcacgc cgggacccat tccatgcctg cagtgttggg ggggattctc
    27001 accattgcgc tggccgatgc catgtccgat gccttgggca tccatgtggc cgaggaatcc
    27061 aagaaccacg ggaatacgca cgacatctgg gcgtccacgg cggcgacgtt tgtggcgaag
    27121 ttcgtcattg ccaccacctt tgcggtgcct gtgttgctca tgcctctgga cctggccatt
    27181 gtggccagcc tgctgtgggg gctgaccctc ttggcattgc tcagttatgc cctggcgcgg
    27241 gcgcaaaggg tgccgccctg gaaagtcatc ggcgagcatg tgatcatcgg actctgtgtc
    27301 gtggccatga cacattatgt tggtgaatgg gtacggctga cgtttgggtg aggatcgacc
    27361 atgaaggaga cgtgtgcagc atggacataa agacgcaatt gccgaaagtg ggcattggcc
    27421 gccggtgcgg agcgatcgaa gcaaatctcg gcggctaccg cagcctcatg agcgatgacg
    27481 agtatgaaga attgaccgcg ttagccaaaa gtttgcaggg catcaagatt tgccacgtga
    27541 actcgacggc ggcgggcgga ggcgtggcgg aactgttggc gcggtatatc cccatgctgc
    27601 aggcgcttgg cgtacaggct gactggcgtt tgattcatgg tgagccggag ttttttgcca
    27661 tcaccaaggc gtttcataac gccctccagg gcgggcatta cgggctggga accaccgagc
    27721 aggacgccta tctgaaggtc aatgaacgca gtgcgcaggc gctgggcaat gactacgatc
    27781 tgtacatcgt gcatgatccc cagcctgcgg ccatacgtca ctttgcggga tcgcgggatg
    27841 ccaaatggat ctggcgctgc cacatcgaca gttcggcgcc ggacaaggag gtcagccggt
    27901 ttctgcgccc cttgttggaa gagtatgaag cggtagtgtt caccatgagc caatttgtcc
    27961 tgccgcagtt ggcggcgaga cgagtggcgt tcatcgcccc ggcaatcgat ccgctggcca
    28021 cgaagaacat ggagttgccg attgatctct gccgccgcgt catcgccgac tccggcgtgg
    28081 atcccgccag gccgttgctg ctgcaggtgt cacggttcga tccctggaag gatccgctcg
    28141 gagtcgtacg cgcatatcgc ctggtcaaag aagagatccc ggaggtgcag ttagtgctga
    28201 tcggcgcgat ggcgggcgac gatcccgaag gctgggaaat tctggatcgc gtggaggaag
    28261 aggcggcgaa cgaccccgac ctctttgtct ttacgaatct ggccggtgtg ggaagcatgg
    28321 aagtcaatgc gttccaacat ggctgcgatg tcgtgattca gaaatcgttg cgggaagggt
    28381 tcggactggt ggtgtccgaa gcgctgtgga aagaaaagcc ggtcgtcgcc ggaaataccg
    28441 gcgggatccc catgcaattc cctgagcctt ttcaacggaa ccttgtcgac agtgtcgagg
    28501 cgtgcgccga gcgggtgcgc catctcctgc atcatcctgg tgcgcgtgcg gagttcgggc
    28561 gggcgggacg tgaacatgtg cgccggcatt ttctgatgcc gcggctggtg cgtgatgaac
    28621 tacggctgat caagcaagtg ctcaacgcat catgatgcag caaaacgata aagctcgcgt
    28681 ggcctacttt tcgatggaga tcggcctcaa tcctctgatg ccgacctatg ccggagggct
    28741 cggggtgttg gcgggcgata cgatccgatc cgctgccgac cttggggtac ccatggtcgg
    28801 agtcacgttg ctgcaccgtc acggctattt ttatcaacgc ctcgaccgga cgggacgaca
    28861 gtcggaggag ccggtggcct gggcggtgac tgattttgcc gagccgctgg acgcccatgt
    28921 ctccgtggag atcgacggtc gcaacgtgca ggtccgcgca tggcgccatc tggtaacggg
    28981 gatgtcaggc cataccgttc ctgtctacct tctcgatacg gatgtgccgg aaaacagctc
    29041 atgggaccgg acaattaccg atgcactgta tgggggcgac gcctattacc gcctgtgcca
    29101 ggaaatggtg ctcgggttcg gcggatttga cctgttgcgc gcactcggac agggggacat
    29161 ctttcgttat catctcaacg aaggacatgc ggctttgctg gtccttgccc tgatggaatc
    29221 cgctatcggg accgcaccgg tgaacggcga ggtgccgccc gaagtgatcg agaaggtgcg
    29281 ggagcaatgt gtctttacga cgcacactcc ggtaccggcg gggcatgatc agttcccggc
    29341 cgatctggcg catcgggtgc tcggacgccg gcgctgcgag ctggcgcagg cgtgccagca
    29401 tcaaggcgcg ttgaacatga ccctgctcgc gttgcgaggg tcccgctttg tcaacggcgt
    29461 ggcgatgcgg catggagagg tttcccattc cctgtatccc ggttatccga tccattcgat
    29521 tacgaacggc gtccatgccg tggcctgggc cgcgccttcg tttcagaatc tgtacgatcg
    29581 ccatctgccg gactggcgat acgatcatct gtcgctccgg tacgccatta gcattccctc
    29641 atcggaaatc tgggctgccc atcgggaagc caagctggcg ctggtggatg aagtgaatcg
    29701 cgaaaccaat gccggattcg atcgcgatgt actgaccatt ggattcgccc gccgcgccac
    29761 ggcgtacaaa cgagcgacac tggtttttca ggatatcgcg cggctgcagc gcctgatgaa
    29821 ggcgaagggg cagatccaat ttgtcttcgc gggcaaggcg catcctcagg atgaggccgg
    29881 gaaagacacg atccaacgga tacacggaat gcgtggacaa ttgcccgttg cgtatctggc
    29941 caattacgat atgaccctgg cgtgtctgct ctgtgccggt gtggatgtgt ggctcaatac
    30001 gccgctgccg ccgatggaag cctcggggac gagcggcatg aaggccgcga tgaacggcgt
    30061 tcccagtctc agcgtgctcg acggctggtg ggtggagggg catatcgaag gcgtgacggg
    30121 ttggtccatc ggtgacaagg ttgaagcctg tctcgctccg gggtcggaca tggaggcctg
    30181 tcatgccgcc gccttgtatg acaagctgga gcagcaagtt ctgccctgct tttaccagga
    30241 ccgcgagcga ttcatcgaca tcatgaaaca tacgatcgcg atcaacggcg cgtttttcaa
    30301 tacgcagcgc atggtgcagc aatacttgcg gaatgcgtat cgactggtcg gatagaccgg
    30361 ccaccggagc ataggcgtat ggctcagcct cacgacagca tgcagtccga ttatagccac
    30421 ttgttgacgc tctggactgc cggggtgcgc gattaccaca cgatgctgtc cgactatctg
    30481 accgccaact ccatctttgt cgccgtcatc ggcctgctcg tgtcacggga atccctggcg
    30541 gtgccgttta ccctcgtgat tgtcctactg agcgcaatcg gcattctcat gagcgtacaa
    30601 atggcgatcg tgttgggccg gttttccggg cagaacgcct tgtgggaatg gcagctgcgc
    30661 gggattgaat ccatgccgga ttggagggaa cggaagccgg tcagtatgct gtaccggctc
    30721 cgcgagcatc gcgaaacgat tgtggatgag acgaatgagc cgcgctcctt cgagccgtcc
    30781 tgggcattcc ggcagcatcg ccaatggtgg gcgcatcggg cgatcagctt cccatggttt
    30841 tttggtacgg tctacggcct ctttttgttg tgggcggtga cgcagatggc gaggtcgagc
    30901 atgatgttct ggtgacccgc cggttgtacg cctcggtgca ccctctcctt tcccttctgt
    30961 gaggagtcat ccttcccgct gttcttttct cgcattccta catgagtcag agatgaagac
    31021 cacatgaaga agtcttcatg gaaggaaacc cctgcgctgt ccctgctatg atggcgctat
    31081 cccacggacg atggccccct tgttcagtcc tcacggtcgc cagtgaaacg aggtatgtat
    31141 gcgaattctg gtcatcgaag acgatgcgga tctggcgcaa tttctgcgta aaggattgga
    31201 ggaggagcgc catacggtgg agatggtcgc cgacggcgaa accggactca tgctggccgt
    31261 ggacgagagt tacgatctcc tgatcgtgga tgtgatgctc ccaaaggtgg acggattgac
    31321 cctgtgtcgg cgtcttcgtg aacgcgggaa tcgttctccg atcctgctgc tcaccgcgcg
    31381 cgattcagtg gaggataagg tcgccggcct cgacgccggg gcagacgatt atttgaccaa
    31441 acccttcgcg tttacggaac tcgtcgcgcg catccgagcg ctcctgcggc gaggcgggcc
    31501 gcacatcggc agccgcctga aggccaaaga tctggagatg gacccggcct ctcgtcgggt
    31561 gtggcggggc gggaaggaca ttacgctgac gagcaaagag ttttccctgt tggagtttct
    31621 cctgcggaac cgcgatatcg tcctcacccg cacggcgatc ctggagcgcg tctgggggtt
    31681 gaactatgat ccgatgacga atgtcgtgga tgtctacatc cgttcattgc gcgtcaagat
    31741 cgaccgggat ttcgacgtcc cgttgattgc caccgtgcgg ggtgtgggct ataagcttga
    31801 ggcgggcgag tgagcagctt ccgggcgcag tttcggctgt atacggtcgc cctgatcgcg
    31861 gtcttgctgg gcgggttcaa cgtcgtcgtc tacacaggat tccatagtct gctgcagcaa
    31921 tatgtggatg ggcgactgtt cgggtttgcc gataccctgg ccgaattgat cgagcagcgg
    31981 ccggaattgc tgaagcggtc cgaccacgaa atcgtggtgc cgcgtggcgc ccaggtcccc
    32041 gacgaccgga tgaaggagct tcgggaagtc tcccattccg tccatatcct gtcactcgac
    32101 ggcacggtcg tgtggcaggg gagcggcgtg gtgccgaggc cctcggtgga tgaggcagtg
    32161 ctggcgcgtg gcaagcgggg ggaagtggtg tatgaaacgc tcgagatgga gtcgggcgcg
    32221 tccgtacgcc aggtctttgt gcccatcagg cagcaggatg aagtgcgata ccttttgcag
    32281 gcagaagaat ctctggcctt cttccgccgg acccatcgca gtctcatggg gctgctcatg
    32341 ttgggatcgg ttgccgtcct ggccacatcc tggttcggca gcgggtggct cgcccgaaag
    32401 gtgctcgacc cggtagaggc cttgagccgc accgccgagg ggatttccga atcggccctg
    32461 cgctcgcggg cgaatctcaa tgcgccgttc gaagaattcg aacgtctggc ccaggcgttt
    32521 aatgccatgc tggaccgctt gcagcgggca tccgaaagcc agcggcggtt taccgactat
    32581 gccgcgcatg agatgaagac tcccctgact gtcatgcagg gcaatctgga agtggccctg
    32641 cagcgcgcgc ggtccgccga agactatcgt gatgtgctcg tctcgaatct cgaacaggtg
    32701 cagcgtctca tcgtcttgac acggtcgctg ctcacgctgg cgcgttttgc cggcgagcgg
    32761 ccgccggtag agctgtcgca gctggcgctt cagccgctgc tcaaagaatt gatcgatgac
    32821 ctcacgcccg tcgcagagga tcggcaggtg accctgcggt tggaagagga gccggtgccg
    32881 ccgatgttgg gagatgctga gcggctgaag caggtcttta tcaatttgat cgataatgca
    32941 gtacggtata cggatccggg agggaccgtg gcgttacgtc tcagcagcag caagaatctg
    33001 gtgcgtgtgg ctgtgcgaga taccgggcag ggcatcgcga gcgagcattt gccccatctc
    33061 ttcgaaccgt tctatcggac cgacccggct cgcgccagag attccggcgg gcatggtctc
    33121 ggtcttccga tcgtgaagga aattgtggag gcgcaccatg gcgccatcac cgtggagagc
    33181 gaagtcggga aagggtcggt gttcatgctg accttccccg ccatccaatc ataatgatgc
    33241 gtccggcagc tcgtcgttct tcctagtcgt gcctatcctc ttttcgttgt cattccttcc
    33301 agccgcatgt cgtcagcatg aagaattctt catgccctac tcatcggcac ttcatctcgc
    33361 gccggta
//
LOCUS       DAOQPD010000040        32992 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_589_length_32992_cov_20.503689, whole genome shotgun sequence.
ACCESSION   DAOQPD010000040 DAOQPD010000000
VERSION     DAOQPD010000040.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 32992)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 32992)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32992
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_589_length_32992_cov_20.503689"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..224
                     /locus_tag="PK063_10660"
     CDS             <1..224
                     /locus_tag="PK063_10660"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97557.1"
                     /translation="QRTRFIRLLGVTHLIWVPMLAWMAVRLAAVPEEDVAFQAWLLAL
                     IATNAISLAIDAWDATRFVRGERQPHYVW"
     gene            complement(851..1249)
                     /locus_tag="PK063_10665"
     CDS             complement(851..1249)
                     /locus_tag="PK063_10665"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97558.1"
                     /translation="MQGFTPAFAYFLIVFGAGFLLGTIRVLLLLPVLGERAAELLEMP
                     FMLIVIVLAARWIDRRFLAGVDDRGRIVVGLLAFGLVLSAEFVVGIALRGMTPRDVLF
                     ARDPVSGAAYYLSLLLFAVMPWLIAPRRRR"
     gene            1616..1990
                     /locus_tag="PK063_10670"
     CDS             1616..1990
                     /locus_tag="PK063_10670"
                     /inference="COORDINATES: protein motif:HMM:NF015674.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HMZ97559.1"
                     /translation="MAQSKQVAALLGPSLIVVSVTELLNLEIFTNTSAHLTYLNGTLP
                     VVAGLTIVRAHNYWMPRWPVRITLTGWLLLLGGLIRMVAPVSSQQTAHHPTAVLAMTA
                     VLLVCGVVLTVNGYRQRDVRDS"
     gene            2069..2485
                     /locus_tag="PK063_10675"
     CDS             2069..2485
                     /locus_tag="PK063_10675"
                     /inference="COORDINATES: protein motif:HMM:NF025054.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HMZ97560.1"
                     /translation="MDIQYKNDTEGVDWERMSELFERVGWGKRKAEDIQAAFRSSSYV
                     RCAYDERTLVGVGRTVDDGQYYALIVDLVVDPQYQGRGIGSNILSYLEHSLANYVFTT
                     LTAAVGKEGFYLNQGWRRHTTSFIWPRTERQRKDHT"
     gene            2822..3130
                     /locus_tag="PK063_10680"
     CDS             2822..3130
                     /locus_tag="PK063_10680"
                     /inference="COORDINATES: protein motif:HMM:NF018599.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1272 domain-containing protein"
                     /protein_id="HMZ97561.1"
                     /translation="MLELRPTCEHCNTPLPPDSPEARICSYECTFCAACVTDVLHNVC
                     PNCGGGFEPRPIRPSKNWRGENYLGKDPASTTIRHRPVDPSAHRAFAATLNAVPPEQR
                     "
     gene            3559..4377
                     /locus_tag="PK063_10685"
     CDS             3559..4377
                     /locus_tag="PK063_10685"
                     /inference="COORDINATES: protein motif:HMM:NF039346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HMZ97562.1"
                     /translation="MVSVPLTNLKNDSINSDDAILLFENGGHKVYWIGTHTGGDEIEC
                     NTYLIIDGHEGYILEPGGFDRFPHVFKKVCLLLSPNSITHLFFSHQDPDICASFPSWT
                     KWNDDIKLVVSSLWTRFMLHYESRDLSGKAHNLNFVKVPDEGLSIPLNDGGRLDCLSA
                     PFLHSPGNILVHDTVSGFLFSGDVGAAMYKDHTFRLVIDDWNAHTQAMQGFHQRYMSS
                     NRAVAGMNKQLAPLPITAILPQHGCIFRGDEVSRFTQWLGKLPVGADYFYPDLA"
     gene            4668..5912
                     /locus_tag="PK063_10690"
     CDS             4668..5912
                     /locus_tag="PK063_10690"
                     /inference="COORDINATES: protein motif:HMM:NF012593.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HMZ97563.1"
                     /translation="MDDNALENTAIVTSQTGVVARWQQIPLYGRIIIGVILGLAAGLA
                     LGNQAAFLATPGKLVLRLLGALAPPLILVAIVHTFMTTHLGGPLAARLPRLLLMNTLV
                     AITVGLTVANVIQPGRGAGLAPAEPAVETTHTANPLVAFIENVPKSLLGPLGDDGKVI
                     GVIFVAVAFGMALRKERHRPLGTVEHLVELVLESLIKILHWIIAVVPLAVFGIVASIV
                     GTEGFAQFQALGIFVLSVLLALTIQAAYYLVRVRFGSWVRPGELLRGGRDALVMAFST
                     ASSTATMPVTYAALKDRIGLREQSASMGALVGANFNNDGTALYEAMAALFIAQMIGID
                     LSMHQQVMIVLTSIIASVGAAGIPEAGLVTMTMVFTAVGLPVQFIPVLLTVDWFLDRC
                     RTAINVMGDMNVSCLLDGKQKG"
     gene            complement(5937..6995)
                     /locus_tag="PK063_10695"
     CDS             complement(5937..6995)
                     /locus_tag="PK063_10695"
                     /inference="COORDINATES: protein motif:HMM:NF005495.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HMZ97564.1"
                     /translation="MMAFSLKPLRQQIIVITGATSGIGLTTARMAARRGARLVLAGRT
                     EGALTELERELSQGQHRAVTVTADVGKAADVQRISRVARQMFGGFDTWINNAGVSMYG
                     RLLDEPIEDMRRLFETNFWGLVYGSLEAARYFKAHDQAGAIINVGSTLSDRALVLQGM
                     YSASKHAVKAFTDALRMEVEMDGIPISVTLIQPGAIATPYSQHAKNYMKTEPTNPPPV
                     YSPETAAQTILYCAENRERHVYVGAGGKGIGMMGYYAPRLADLLMETLFARQQQSDRP
                     PARPRRDNALDRPSGDLRERGDYQGHVSESSLYTTASLHPMLTGAALVGAGLALKTLW
                     PSKHTSERVQNAPRAQRR"
     gene            7431..8435
                     /locus_tag="PK063_10700"
     CDS             7431..8435
                     /locus_tag="PK063_10700"
                     /inference="COORDINATES: protein motif:HMM:NF012425.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase family peroxidase"
                     /protein_id="HMZ97565.1"
                     /translation="MWRSRIATAALAVALISPLSVLAEEPPANPKSLAEQLVDAFNGV
                     FGVHPGMRANHPKGMVLEGTFTPTASAASVSKAAHLQKKKTAVPVTVRFSAGSGQPSV
                     PDTSQMPRGMAVKFSLPDGSKTDLVVLSFNGFPVATAEEFRDFLLAVGASGPDAPKPT
                     PIEQFLATHPAAKHFVESPKPQPVSYATLPYFGINAFKFTNAKGHVTFGRYQLRPMAG
                     EHFLTQEQLNTMDPDYLSAEIRERLRRGPAKFTLLLQVAEKGDKIDDPSIAWPDSRKQ
                     IKLGTISITKAVADSQAAEKKLLFMPGALVPGIEAADPMIAARSASYVVSLSRRAQAQ
                     "
     gene            8515..8925
                     /locus_tag="PK063_10705"
     CDS             8515..8925
                     /locus_tag="PK063_10705"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97566.1"
                     /translation="MARWSRVWLGPEGLWLMISLAVYVAAAMNQPSTPAGNDFLETLW
                     VAIPLVGIPLTFATALLPRGSGWWWLTRVVVASCIGVIVASFIAAGGVDYHDSRNSGL
                     LGAPVYSLSIGLLLLFPLTILAILLIWKKRRTSR"
     gene            9136..10452
                     /locus_tag="PK063_10710"
     CDS             9136..10452
                     /locus_tag="PK063_10710"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF014414.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HMZ97567.1"
                     /translation="MTLSRKTIHDSTGLLGELLAQYHPRNFDIRLWDGTIWPADPGAT
                     PEFTLILRTPTVLRDMLWKASELALAEAFISGDLEIDGDLEQAIPLAEYLSRHPVTWG
                     SWLRLGFKSLRWPSNPSFTTNGLAAHVTGPNHSLLRDKQAIAYHYDHPPEFYAGWLDP
                     QMVYSCAYFSFTDDLDAAQVHKLDYLCRKLRLRRGERLLDVGCGWGALIVHAARYYGV
                     QACGITLSEKQAEFAEACIQQHGLMDRCQVELRDYRQLSTPNRYDKIVSVGMVEHVGA
                     THLSGYFRHIWNLLKPGGTFLNHGIGIRHGERCAFGPFVNTYVFPDAELTTISTTTGF
                     AETAGFEVRDVECLREHYVLTLRQWRQRLEKNVTPGSSSMDESTWRLWRLYLASAAHG
                     FATGKLNLYQTLLSKTQEGSAGLPLTRDDWYEAHSSIDSRLSGRLR"
     gene            10620..10991
                     /locus_tag="PK063_10715"
     CDS             10620..10991
                     /locus_tag="PK063_10715"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97568.1"
                     /translation="MKRDTWLVVTAVTGGIVVWLLVSAFAHKREAWDSDLYFTLGLPA
                     VCLLSALLGYLEPNRAWRWGAAPLVGQALVMLLTQGPGTVLPLGIMMFGVLALPSIVT
                     AKMGAYAAKRSPHGSTARQNH"
     gene            complement(11016..11897)
                     /locus_tag="PK063_10720"
     CDS             complement(11016..11897)
                     /locus_tag="PK063_10720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006946080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HMZ97569.1"
                     /translation="MRIATWNVNSLKARLEKVLWWLDRAKPDVLLMQETKLSDADAPI
                     DAFAQAGYALAHHGEGRWNGVAIASRCGISGVISNFGEPLQPARSTDTGDDEPFAEAR
                     MLAADCGGLLIICLYAPNGREVDSPFYEAKLVWFDKLARWLKQTGAPQKACVIGGDFN
                     VAPQDIDVWDPAACHGGTHVSDRERRAFDRIVREGFVDAYRCHHPEPGRYTWWDYRAG
                     NFHKNIGMRIDHLLVSTPLRDRVIWSEIDREARKGKPLPSDHAPLVIDLDTAGHPFDA
                     GWVSAESRIAARTGKKR"
     gene            complement(11965..13617)
                     /locus_tag="PK063_10725"
     CDS             complement(11965..13617)
                     /locus_tag="PK063_10725"
                     /inference="COORDINATES: protein motif:HMM:NF012356.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HMZ97570.1"
                     /translation="MTLLQPNTPWWQSAIVYQIYPWSFQDSNGDGIGDLPGIISRLDY
                     LNGSPDSLGVDAIWLSPIYPSPMHDFGYDVSDYCDIDPRFGTLADFDRLVSEAHRRGI
                     RVVMDLVLNHTSNQHPWFIESRSSRTSAKRDWYYWADGKSGRRPPNNWAARFGGSAWT
                     HDPHTGQYYLHSFLSEQPDLNWTNPAVRDAVFGVVRFWLDRGVDGFRLDAINWLGKDT
                     SWPDNPRRLAWRSYYRQIHRYDRDQPHTHEALRALRSSLKDREDILLVGETSSDTPGG
                     PAAFYGNGSNELHEVFDFRLLRSNWHPETFRRLILDSDRAVPQGGWPPVVFSNHDQSR
                     HIDRYGAGGEAIRRARAAALLLFTLRGTPFVYYGEELGLHDGRLRRADLHDPYTIRYW
                     PWKTGRDPARTPMPWDDSPQAGFTTGRPWLPLSHAWRQTNVAGEQRDPASILSLYKRL
                     IRMKKGSNALTVGAYHPVDGGPPECLFFTRESLVDGQRDALFIAVNFSAHTQKISLPA
                     GPSKLGRHGTLMLSTDPLRAEGPWTADHFLLGPDEGIVVSMQ"
     gene            complement(13932..14195)
                     /locus_tag="PK063_10730"
     CDS             complement(13932..14195)
                     /locus_tag="PK063_10730"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97571.1"
                     /translation="MKAKRTMHVLTNKKGAIVGGGLLTPGKDHKGKPVHIQIEPMKGQ
                     SLKEVAVPDELARLEGADFFSRLMCDFHLPRGKKELVRRGSKR"
     gene            complement(14218..14520)
                     /locus_tag="PK063_10735"
     CDS             complement(14218..14520)
                     /locus_tag="PK063_10735"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97572.1"
                     /translation="MAFNQVGDFWLAPGEAIRVHIARGKLVPDEEWGGEDFGAQWIMA
                     DGVGINPVRLMVSEHTKEKKALRRHPGPSGPVVYSVTVTNIGEELAHFTIQGGGNV"
     assembly_gap    14589..14688
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            14817..15245
                     /locus_tag="PK063_10740"
     CDS             14817..15245
                     /locus_tag="PK063_10740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DCC1-like thiol-disulfide oxidoreductase family
                     protein"
                     /protein_id="HMZ97573.1"
                     /translation="MTTIDPTRHEWARFERLIVFDGICNWCNAWVNFTMARDRGRFHF
                     ATLQSAKGQELLTLLGLPVQDFETFLLLERGQVFTKSTAALRIARTLSGWWPLLYGFI
                     LIPRGLRDILYNYVARHRYRLMGKADTCRIPSATDRDRFV"
     gene            complement(15242..15466)
                     /locus_tag="PK063_10745"
     CDS             complement(15242..15466)
                     /locus_tag="PK063_10745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010512346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2945 domain-containing protein"
                     /protein_id="HMZ97574.1"
                     /translation="MDQNFKVGDHVSWNSEAGRIRGTIQKRITAPMKFKSYIARASKE
                     QPQYLVKSDKTGHLAMHKGTALRKIGGQSA"
     gene            15607..16125
                     /locus_tag="PK063_10750"
     CDS             15607..16125
                     /locus_tag="PK063_10750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97575.1"
                     /translation="MDIVSHGLWGALAFGRRSRTSFWLAFGIGLAPDLFSFGILWAAA
                     TLGLSPKPDFSHGTPPESTIPPYVHHLYDVTHSFVVFLAVFALLWLVMKRPVWELGAW
                     GLHVLVDIPTHSFAFFPTPIFWPLSDWKFDGWQWSQPAILIPNFTVLLLLYGWFLFQQ
                     ARPILRPERARD"
     gene            16238..16618
                     /locus_tag="PK063_10755"
     CDS             16238..16618
                     /locus_tag="PK063_10755"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97576.1"
                     /translation="MANRKREPVPTPQSIASYVKRHAPRVKQSQRRHHAATETIREAD
                     HQGHHIVVKTRYEISVDGRKVLGHLGVSNDGHVHYHPIPNLSFASALDMVKAIIDVFP
                     HQFEAKKRPHKGPGRIRHTNRTHH"
     gene            16628..17584
                     /locus_tag="PK063_10760"
     CDS             16628..17584
                     /locus_tag="PK063_10760"
                     /inference="COORDINATES: protein motif:HMM:NF012486.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosinase family protein"
                     /protein_id="HMZ97577.1"
                     /translation="MAVTRRNILTNANVRAQYARGVNLLKREFTGPTTSSLGIPGPAR
                     QISTYDLFVVWHHTAMSTMTPPSQGDRNAAHRGPVFFPWHRFMLIELERNLQRVLRDD
                     TFGLPYWDWAADGSRTPGQQRQSALWRASGVGGTGSPVRTGPFRFVADDPDSFRIRVE
                     ADANGRLIQSNRGLRRDLGVNIATLPTRTDTAGALALTLYDQPNWDTTSAGFRNRAEG
                     WAAPDAPALHNRVHVWVGGDMLPSSSPNDPVFYLNHCNEDRLWEAWMARHTRAYVPTQ
                     SAPASLRGHRLNDQMLAFVSAAMRPADVLDVGSIYVYDSLAV"
     gene            17760..18500
                     /locus_tag="PK063_10765"
     CDS             17760..18500
                     /locus_tag="PK063_10765"
                     /inference="COORDINATES: protein motif:HMM:NF012955.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HMZ97578.1"
                     /translation="MAASQTYTVTILLDVNEAQDVDDRAESRSYLVADHSSSQAVIID
                     AVLENIERDVRILKELGLTLAYAIETHVHADHITAASLLKDRTGAQIVYGGGAAGTVM
                     GADLFLSDGQTLRFGGSALTALATPGHTDGCTSYLLPGAVFTGDALFIRGNGRTDLQG
                     GSAATLFDSVRQKLFALPDDTIVYPGHDYQGRVASTIGEEKRFNERLNLSIDKDTFIE
                     LMNRRKQPRPAKIDIAVPANLRAGRMAR"
     gene            18693..19211
                     /locus_tag="PK063_10770"
     CDS             18693..19211
                     /locus_tag="PK063_10770"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97579.1"
                     /translation="MSHEQIAAPGPEWGIVIGSVLVRQEQKGSGADTAVRDQSTMFEV
                     EVVQVQPGDPNGESPYAARYHVDATAGLDRPFLARLRPGRYLIKNFYRTGMAGTGGDL
                     NLVFESQSGRVVYIGQLLVEVPPQLTHGKDYRFSVHDTHDITLSQLAPHHRDLTQQAT
                     TVPMQIREKDSH"
     gene            19404..20090
                     /locus_tag="PK063_10775"
     CDS             19404..20090
                     /locus_tag="PK063_10775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HMZ97580.1"
                     /translation="MSHNLKLSLCLNLILLGFILTGYVGPSVKTTFMPDVEAPVIGNH
                     TRIHPLGIVIGSVTLGDRVFVAPAASVRGDEGRHIHIGNESNVQDGVVVHGLETFEGD
                     HELPENEVEVDGMKYSVYIGNRVSLAHQSQVHGPARVGNDTFIGMQALVFRAEVGDRV
                     VVEPGAKIIGVKVPSGRYVPALSVVTTQDVADNLPLITERYPYRNLNGGVVRVNVQLA
                     EARQPQPIAR"
     gene            complement(20155..21363)
                     /gene="ilvA"
                     /locus_tag="PK063_10780"
     CDS             complement(20155..21363)
                     /gene="ilvA"
                     /locus_tag="PK063_10780"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: protein motif:HMM:NF005600.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - L-threonine ammonia-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0006549 - isoleucine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HMZ97581.1"
                     /translation="MVTVQSIAAAASRIASSIYESPLVHSRTLSRLTGNTIYLKLENL
                     QMTGSFKERGALNRILMMTEEERRRGVIAASAGNHAQGVAYHAVQRNIPVQIWMPRST
                     PLVKLSATRNHGADVVLHGENYDEACRAAMERSEERHATFIHPFDDDEVIAGQGTLGL
                     ELLRQNPTLDVIVVPVGGGGLIGGVGCAVKEQASNVEVVGVQTARLPSMKAALGSSIP
                     VELPASPTLADGIAVRTAGSRTLPLVQRYVDQMVTVDEDEIAAAILRLLEGEKTVAEG
                     AGAVALAALLQGNTGHRGKNIAVLVSGGNLDVNLLARIIERGMVRDGRRLRLRVLLPD
                     YPGSLEGLTSVIAKASANIVETSYNRAHYGVGLNEAALDVTMETRGREHASELLAALS
                     GSRYEFSVIE"
     gene            21835..23286
                     /gene="pyk"
                     /locus_tag="PK063_10785"
     CDS             21835..23286
                     /gene="pyk"
                     /locus_tag="PK063_10785"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HMZ97582.1"
                     /translation="MSSSLVESTMQKTRIICTIGPATDSYEMLQKLYDAGMSIARLNM
                     SHGDHESHAKVIQHIKSLNRKVKFPIPILLDTQGPEIRTGDLSNELNLRQGEIVSVTT
                     RGPLNVEESSIHINYADLLDAVNVGDRITVDNGLINFEVLEKHERHMRCRVLDGGLLK
                     SKRHVNLPGVRVNLPAITPKDTKDILFGLERDVDFIALSFVREAGDIQQLKALMGDKV
                     GRVKIIAKIEDQEGVKNLESIIKESDGIMVARGDLGVEINLEDLPNVQRTIVRLCAEY
                     GKRVIVATHLLESMIHHPHPTRAEVTDVANAIYEEADAVMLSGETTVGKYPVKCVEYL
                     RRIALKSETIPGLQFAKRLRDVGNKQQLAAAAVQLAEGVKAKGIVVITRRGIMADLVA
                     NCRPFVTNIYAFTNMSQPRRTMLLNRGVFPFKIDFSSEPEKTLQTAFRILKDRERFQA
                     GDKVVIISDVLAQQRVDSIQIRDVPSDDLPVDA"
     gene            complement(23291..23737)
                     /locus_tag="PK063_10790"
     CDS             complement(23291..23737)
                     /locus_tag="PK063_10790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SRPBCC family protein"
                     /protein_id="HMZ97583.1"
                     /translation="MPTNTVRLHRVLRSTPERIYRAFLDADAMAKWLPPNGFTGNVHH
                     MDAKVGGTFKMSFTNFTTGKSHSFGGKYLELTPYERIRYTDVFDDPNLPGEMHVTITL
                     KQVSCGTEMTAVQEGIPEMIPVEACYLGWQESLTLLTKLVEAEIPD"
     gene            24010..24699
                     /locus_tag="PK063_10795"
     CDS             24010..24699
                     /locus_tag="PK063_10795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2959 domain-containing protein"
                     /protein_id="HMZ97584.1"
                     /translation="MNVRHRSITHACASITLTCGLVLVSLTGSGCQTAYYETMEKLGY
                     HKRDLMVSDVKKARDAQQDAKEQFKSALDRFTKTLNIQGGELQDKYEVLNSEYQQSEK
                     RAEAVRSRIASVEDVSDALFTEWEGELKQYSNASLRQKSQKQLAQTRTQYGQLIKAMK
                     RAEAKMDPVLAKLKDHVLFLKHNLNAQAIASLKSELTTVEGNIDLLIKDLNASIHEAD
                     TFIASMEKENA"
     gene            complement(24786..25181)
                     /locus_tag="PK063_10800"
     CDS             complement(24786..25181)
                     /locus_tag="PK063_10800"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97585.1"
                     /translation="MDQQHQRSRGTGGGLFAGFLVGFLWFFLSFAAMFNGVFFLLLLV
                     PPAYALSGALLAWFFRLPPVHAACSLVGSALPWVAWLWPATMSSSGWMKSLVWPVFVG
                     TAFGMSLLGARLAAARRRRKPTQSDPALA"
     gene            complement(25236..26141)
                     /locus_tag="PK063_10805"
     CDS             complement(25236..26141)
                     /locus_tag="PK063_10805"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97586.1"
                     /translation="MRRTWVGLAAVFMLAMVIGVMPAVVRADCVDGVRDPTSEELAFA
                     ARAEAALAAALPSPIANSERRGGTYDFSRQPRLSFCTSNQVGAFIPNVSGGYLYKFPK
                     AEADRLYAERKAVEKQIEEAEKLPPEKDAEYKQVLAQMKAAYDAAPRRSRKDPPFTPE
                     QQEQVTRAMAEGKKLEDAAKKLLSDHVASVKSQTDPLRAQAKRLESYPQDLAVRLAMN
                     MERFPEPGPTIATFGAPSARRSGGLAVHNVVIAVEGPEGAARQALFDAVDKGYLQGLV
                     GQPLPELEASKARAGRDTQAASAAK"
     gene            26287..27513
                     /locus_tag="PK063_10810"
     CDS             26287..27513
                     /locus_tag="PK063_10810"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ97587.1"
                     /translation="MTTQASPSSDDQSDTPTPHRSPDPAPDGPRPAATELDRFFELSL
                     DMLCIANADSYFTRLSPAFTRTLGWSLEELMSRPFLDFVHPDDRAMTLLEVERQIGRG
                     EPVLEFQNRYQHKNGSWRLLSWKSSPHPDGRMYAIARDVTDREQAQQALRRSHEELEH
                     RVQERTAELQQRNRDLETLLYVSSHDLREPLRSISNFSQLVRDRYGDRLDAKGLDYID
                     RVVRAAQRMDQLMEDLLTLSRAQRLEMPYEDVPGEDVVKAALTQLDETIRRTGARVQV
                     AANFPWFRVNKTWITQALYNLIANALKFHLAGKVPEIEIAPFYLTEETVPLAGIVVRD
                     RGIGVEPDQAQRIFQLFQRAVGREVSGTGAGLAIVQQIAHRHGGRAWVQPREGGGSEF
                     VLLFGSQSVIGKKPAS"
     gene            complement(27722..28897)
                     /locus_tag="PK063_10815"
     CDS             complement(27722..28897)
                     /locus_tag="PK063_10815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HMZ97588.1"
                     /translation="MKLYRSFILTLGLLLACNTLASAEILALLNYESKPDQTVRREGI
                     AIMDIDPESGNFGKILMEIPLPPDLVAHHIFFNRDRSKAYVTALGKSILHVVNLTEFP
                     YRLRAIDVPDCQMGEDLAVSEDNRTWYLTCMGSNNVIMGDALLDKPIKTVSAAEPALA
                     TIQYPHGIAIHNGIDRVLVTSTVKPDMSDAGDSITVMEAGSGRVLSTHKVSAKPSPAK
                     AAPVEVMFSPNSNPPAVHITNMLEGTLWAGLWDPASKTFSFHQVDDFGPRQQGMPLEM
                     LYNAKGDRLFVTTAKPGFVNLYDNSDPGQPKFLKTIAAAAGAHHSVLSPDERYLFVQN
                     SFLNLDGMSDGSITVIDLKADTILGNIDTLKAQGFNPNCIMLLPTQPGDLRASRVTE"
     gene            complement(29028..29378)
                     /locus_tag="PK063_10820"
     CDS             complement(29028..29378)
                     /locus_tag="PK063_10820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HMZ97589.1"
                     /translation="MTNATTTEIDQTTGLYDMTNLGRVKDLGAHAPEAMKAFVAFDKA
                     ALAPGAIPGKYKELMALAVAFTTQCPYCIELHANKAKEYGASAAEIAESVLVTAALRA
                     GGAVTHGTHALKGI"
     gene            complement(29410..30231)
                     /locus_tag="PK063_10825"
     CDS             complement(29410..30231)
                     /locus_tag="PK063_10825"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HMZ97590.1"
                     /translation="MTTNTIMPELDSLKTRLNTIWTAGDYDRFSRYMEGGAREFYERL
                     QIAPGCRLLDVGCGSGQLALIAAKDGLEVTGVDIAANWVERAQARARAEGVSARFEVA
                     DAEALPYETASFDAVTSLIGAMFAPRPDLVAQELLRVCTPGGTLAMANWTAEGFVGQM
                     FKNVAKFIGPSGMPSPVLWGNEATVQERLGHGLSTISLTRRQYLFSYPFPPSEVVEFF
                     RLYYGPTNRAFASLEAEGQAHLRRDLETLWAAHNQAGPDCTTVYGEYLEVIGIRS"
     gene            30427..31446
                     /locus_tag="PK063_10830"
     CDS             30427..31446
                     /locus_tag="PK063_10830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HMZ97591.1"
                     /translation="MDVLSEVLKAVKLDGAVFFHGEFAAPWCAQEPDAETMASYLPTQ
                     AGHIIIFHLLLEGRGYIRLGDEDRAVPLTAGDIIILTQGDAHYMGNGPPVTPVDTSLQ
                     IRQILAEGRMMSQLAGGGEITKLICGYLTCDAQLCRVVLAGLPAMLKVNIRDTPSGHW
                     LENTLRYSVDHAEASGPGGAAVIAKLSEALFVETLRRYIAQLPHTETGWLAGVRDPDV
                     GKALALLHQRPAQPWTIATLAAEVGVSRSVLAERFQHFLADTPIGYLTRWRLHLAAQL
                     LTSTSKSVAEVAGDIGYESEPSFNRAFKREFNLPPARFRAQSKASLAGNGAVSRQDHR
                     SAPAR"
     gene            complement(31422..31760)
                     /locus_tag="PK063_10835"
     CDS             complement(31422..31760)
                     /locus_tag="PK063_10835"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97592.1"
                     /translation="MKTIVLCVCMSLLLPVMSEARCRTIGESASLGSEYGTFPLYPAE
                     QVVEAGQKRKSIAMQWLGYGIGVPLFVVAMPFAMVGAVAGAAAHPWTKCKAMEGRFEG
                     PEVHLAGADR"
     gene            32249..32731
                     /locus_tag="PK063_10840"
     CDS             32249..32731
                     /locus_tag="PK063_10840"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97593.1"
                     /translation="MLFHTSASGIEQPSALQADTALSARLLVSWLVFWILALPLMHVH
                     IQAERHQGLPHNVLAGDLPGEFVSSADSAIEAAQPAGVPPPPHLASGISYPELAFTAP
                     VPSKHHWLFSLTAIFTRDIPAEMFPTGRTVTPDQRSFDHPTPLPLSSPRAPPPVDRLT
                     "
BASE COUNT         6758 a        10038 c         9346 g         6750 t
ORIGIN      
        1 atcagcgcac gcgcttcatt cggctgctcg gggtgacaca tctgatctgg gtacctatgc
       61 tagcctggat ggccgtgcgt cttgccgcgg tcccggaaga ggacgtcgcg ttccaggcct
      121 ggctcctcgc actcatcgcc acgaatgcca tctcgttggc gatcgatgcc tgggatgcca
      181 cgcgtttcgt ccgtggcgaa cgtcagcccc attacgtctg gtgatgagga gagaggaaag
      241 cggaagaaag tgaccactcc tcgccgggct aagcgcgtct gacaaagact cgctcgatac
      301 tgattgcctt gagtgttgtt gattgcgggc catgcccaat ctgcgggcaa tcacggtctg
      361 acaatcgcac attccgtctg ccgacgcaga cactcgaacc agacgtcgtt atttcgtcct
      421 tgcccggttc tttttccaca ccagagcagc agcgacgagt gtaagtggca ccagcagtac
      481 aatcccaatc gagagactgt atgcgggtgc gccgagcaaa ccggagtttc gggaatcgtg
      541 atagtcgatg ccgcgagcag aactggtgac tcgcgcagaa gagcggcaat gatcgagcga
      601 gcggtggcgg gactaaggag atgccaagct gacagctcgg ctcagtgact gactcgtgac
      661 acggccaggc ggttgggtga cgcgtgtgaa tcgcccacag accgcatcgg agctgcaatc
      721 actctgaaac aatgagcaac ggggccgccc gaacagtgaa gaagcctgtt gcggcggatg
      781 gcgaaacagt ttggactgga atcaagcaga aacaaagttg ccaggaattg ctccttcctc
      841 cacgctgccg ttaccgccgg cggcgtggcg cgattaacca cggcatgacg gcaaagagca
      901 gcaggctgag gtagtaggcc gcacccgaaa ccggatctct agcgaacagc acatcccgtg
      961 gcgtcatgcc acgaagcgcg atgcccacga caaactctgc actcaagacc agtccgaacg
     1021 ccagcagtcc cacgacgatc cgcccccggt cgtccacgcc cgccaaaaaa cgccgatcga
     1081 tccaacgagc cgccagcaca atgacgatga gcatgaatgg catctccaag agttccgctg
     1141 cccgttcacc caggaccgga aggaggagca ggacgcggat tgtcccgagg agaaatccag
     1201 ctccgaagac aatcagaaag taggcgaacg ccggtgtgaa tccctgcatg aggcgctagg
     1261 ctagctaaat gaccattggc tgtaaaggct ttcgacgggc gcgtccgggc gatgtctgac
     1321 ggaaggcgta cgatgccagg aatcattcgg cccgagcctg gtacccattc cggctgcgac
     1381 ctggctcttt gggtctggcc ttgcggtgct ggatgcactg aaagggactg gcaccaagga
     1441 gtgcccttct gaagccggcc caagtcttct ttcatccttg gcacctccgg cccatcgccc
     1501 acgcaccaac cacatgcgtc acgcaataga ccaaacccac cggaaacagt acaatgctgc
     1561 cggggcctgt cctgtgaaac tgctggcgcg ctgaggccgg agaacagagg gtgaggtggc
     1621 acagtcgaag caggttgcgg cactgctcgg gccgagcctc attgtcgtct ccgttacaga
     1681 gttgctgaac ctcgagatct tcacgaacac gtccgcgcat ctcacgtacc tcaacggcac
     1741 tttgcccgtt gtcgcgggct tgactattgt ccgtgcccac aattattgga tgcctcgctg
     1801 gcctgtgcgg atcacgctca cagggtggct actcctcctc ggtgggctga tccgcatggt
     1861 cgctccagtc tcgtcccaac agaccgctca ccatcccaca gccgtattgg ccatgacggc
     1921 ggtactgttg gtgtgtggag tcgtcctgac cgtcaacggg tacagacaaa gagacgtgag
     1981 ggacagctga ccggcgcgaa gagcagaaga ctgtgaacgc gagtcatgct accagggctc
     2041 atgtctcacc ctagcaagag aacaacccat ggacatacag tacaagaatg acacggaggg
     2101 tgtggactgg gagaggatgt ccgagctctt cgaacgcgtc ggttggggga aacgcaaggc
     2161 cgaagacatt caggctgcct ttcgatccag ctcctatgtt cgatgtgcct acgatgagcg
     2221 tacgttggtc ggtgttggac gtacggtgga tgacggacaa tactatgcat tgatcgtcga
     2281 tttggtggtt gaccctcagt atcaaggccg tgggattggc agcaatatct tgtcgtatct
     2341 cgaacactca cttgccaact atgtgtttac gaccctgacg gcggcggtgg gcaaagaggg
     2401 gttctatctc aaccaaggat ggcgcagaca caccacgagt tttatttggc ctcgcacaga
     2461 gcgacaaaga aaggatcaca cgtaatctac caagggccca gcatgatgcc ccaccagcga
     2521 ggctgccctc gatgaaggcg agctgatgcg gcgtccctcc ggcgcgcggc agacagttca
     2581 ccttgggccc ccatcgcgtc agtcgagcca gcgatgaatt ccctcaagac cttccacaga
     2641 gtgtctgccg gtcaggagag gaacttcacg tgcgaggtac cgaaccgtct cgcgagggta
     2701 accggattcc ggcccaacgc cggctggagg caagaactcc cctcgttact ctcccataga
     2761 tcctcgaggc ttgagcgcgt agaatggaca catgaccatt ccttagcgaa ccagatccat
     2821 catgctggaa cttcggccaa cctgcgagca ctgcaataca ccgttgccac ccgattcacc
     2881 cgaggcgcgc atctgctcct acgaatgtac gttttgcgcg gcatgcgtca cggacgtgtt
     2941 gcacaatgtc tgccccaatt gcggcggcgg cttcgaacca aggcccatca gaccgtcgaa
     3001 gaattggaga ggggagaact atctcggcaa ggacccggcg agcacgacga tccggcatcg
     3061 gccggttgat ccctccgccc atcgcgcatt tgccgccacg ctcaacgctg tcccacccga
     3121 acaacggtag ccactcgctc caagacgacg ccaggaaatg gtcccaggaa tcatccagac
     3181 ctggatacgt aacaggggcc cagccgaacc cttttgtcag gcgcctcatg catattccga
     3241 gaaggcgccg aacctctcta acacgtagag tccaagctag gacacgcagg tctgcgagag
     3301 tgaacgactg caggcgcgta acctactcac acgcctgcct tgggagaatg tcagcggttc
     3361 acgtaccata ctgatacaca acgacacctg gccccatgca acagacaacg ggccaggcac
     3421 catttttttc tccaagaact tccccttcag gctcccctca ttcgcgtatt ccgtttgtga
     3481 tcagtggatg ttcctctata atttcactta ggggtgcgga ggccgggccg tgtagtgatg
     3541 taccggatgg aggttgccat ggtgtctgtt ccgctgacca atctcaaaaa tgattcgatc
     3601 aactccgacg acgccatcct gctgttcgaa aacggtggcc acaaagtcta ttggatcggc
     3661 acacacaccg gaggagacga gatcgagtgc aacacctatc tgatcatcga cggacacgag
     3721 ggctacatcc ttgaaccggg cgggttcgac cgtttcccgc atgtgttcaa gaaagtgtgt
     3781 ctcctcctca gcccgaatag catcacccac ctgttcttca gccatcaaga ccccgatatc
     3841 tgtgcctcat ttcccagttg gacaaagtgg aatgacgaca tcaagctggt tgtgtcgagc
     3901 ttatggaccc ggttcatgct gcattatgag tccagggacc tgagcgggaa ggcccacaac
     3961 ctcaatttcg tcaaagtacc ggacgagggc ctttcgatcc cgttgaatga cggcggccga
     4021 ctcgattgtc tctccgcgcc atttctgcac tccccgggca atattcttgt tcacgatacg
     4081 gtcagcgggt tcctgttttc cggagacgtc ggcgcagcca tgtacaagga ccacaccttc
     4141 aggctcgtga ttgatgattg gaacgcgcat acccaagcca tgcagggatt tcatcagcgc
     4201 tatatgtcca gcaatcgagc tgtcgccggg atgaacaaac aactcgcgcc actgccgatc
     4261 acggcaattc ttcctcagca cggatgcatt tttcgcggag acgaggtttc acgcttcacc
     4321 caatggctcg gtaaactccc cgtcggagcc gactatttct accccgacct ggcgtgactc
     4381 ctacgggccg gggttggtgc cgctgcaacc cggcctgacg gtggtccatc atccgccacg
     4441 cctgctcaac tatacgcatc aagtcatggc tgcgattcag tatcgatcgg gcaagcccac
     4501 ggctgcagtg cgagctgaac gcggcgtgaa tactcttgca tccatctccc cactgcagaa
     4561 gcagatctga tagtatccgc cacaatcgac aaggctcctt ctaaccttgt cccgttaaca
     4621 caactgcgca ttccctgaga aacaggaaca catcggagta ctcgttcgtg gatgacaatg
     4681 ccctagagaa cacagccatc gtcacttcgc agacaggcgt ggtggcacga tggcagcaga
     4741 tcccgctgta tggacgcatc atcattggcg tgatactggg ccttgcagcg gggctcgcgc
     4801 tgggaaacca ggccgccttt ctagccacgc cgggcaagct ggtgctccgc cttttggggg
     4861 cgctcgcgcc gccgctgatt ctggtcgcga ttgtccacac cttcatgacg acgcatctcg
     4921 gcggcccgct ggccgcacgc ctcccccgat tgctgctgat gaatacgttg gtggcgatca
     4981 ctgtcgggct gaccgttgcc aacgtcatcc agcctggacg aggtgcggga cttgcgccag
     5041 cagaacccgc cgtcgaaacc acgcatacgg caaatccact cgtggcgttt atcgagaatg
     5101 tgcccaagag cctgctgggg ccgcttggtg acgatggaaa agtgatcgga gtcatcttcg
     5161 tcgcggtggc cttcggcatg gctctgcgta aggagcgcca tcgcccgctc ggaacggtcg
     5221 agcatctcgt cgaactggtg ctagagtcct tgatcaaaat tttgcactgg atcatcgcgg
     5281 tggtgcccct ggcggtgttc ggcatcgtgg cgagcattgt aggaacagag ggtttcgcgc
     5341 agtttcaggc gctgggtatc tttgtcctca gcgtgttgct cgcgctcacg atccaggctg
     5401 cctattatct cgttcgcgtt cggttcgggt cctgggtccg tccgggtgag ttgcttcgtg
     5461 gcggacggga tgcgctggtc atggcgtttt ccacggcgag ttcgacggcc acgatgccgg
     5521 tgacttacgc ggcgctcaaa gatcgcatcg gcctgcgcga acaatccgcc agcatgggcg
     5581 cactggtcgg ggcaaatttc aacaacgacg gcaccgcgct ttacgaggcc atggcagccc
     5641 tgtttattgc gcaaatgatc gggatcgatc tgagcatgca ccaacaagtg atgatcgtcc
     5701 tgacgagcat cattgcctcg gtcggcgcag ccggtattcc cgaggcaggt cttgtcacca
     5761 tgacgatggt cttcacggcc gtcggcctcc ccgtccagtt tattcccgtc ctgctcacgg
     5821 tggattggtt tctcgatcgc tgccggacgg cgatcaatgt catgggcgac atgaatgtga
     5881 gttgcctgct ggatgggaag cagaaaggat gaatcagcgc aaactctgac gaaggatcaa
     5941 cgtcgctgcg cgcgcggtgc gttctgcact cgctccgagg tatgtttcga tggccacaag
     6001 gtcttcagcg cgagtcccgc gccgacgagt gcggcccctg tcagcatggg atgcagggat
     6061 gcggtggtgt agagactcga ttccgacaca tggccctgat agtcgcctcg ctcccgcaaa
     6121 tccccggacg ggcggtccaa ggcgttgtcc cggcgaggcc tggcgggggg acgatccgac
     6181 tgttgttgtc gggcaaacaa tgtttccatc agcaggtcag ccagcctggg tgcgtagtag
     6241 cccatcatgc cgatgccttt cccgccggcc ccgacgtaga catggcgctc tctgttctcg
     6301 gcgcagtaca gaatggtctg ggcagccgtc tcgggtgaat acactggcgg cggattcgtg
     6361 ggctccgtct tcatgtaatt tttggcatgt tgtgagtagg gcgtcgcaat ggcgcccggt
     6421 tgaatgaggg tgacggagat cggaatacca tccatctcca cttccatgcg gagcgcatcg
     6481 gtaaatgctt tcacggcatg cttggaggcc gaatacatcc cctgcaacac cagggcgcgg
     6541 tctgagaggg tactgccgac gttaatgatc gccccggcct gatcgtgcgc tttgaagtac
     6601 cgcgccgctt ccagtgaccc gtacaccaat ccccagaaat tggtctcgaa caatcgccgc
     6661 atatcttcga tcggttcatc caggagccgt ccgtacatcg acacgcccgc gttattgatc
     6721 caggtgtcga accctccgaa catctgtcgc gcaacacgtg atatccgttg cacatcggcg
     6781 gccttcccca cgtctgccgt cacggtcacg gcccgatgct gtccctgtga caattcccgc
     6841 tcgagttcag tcagcgctcc ttctgttcga ccggccagaa cgagtcgcgc ccctcgtcga
     6901 gccgccatcc gcgcggtggt caggccgatg ccggatgtcg ccccggtgat gacgatgatt
     6961 tgctgacgaa gtggtttgag cgagaaggcc atcatgagag ttcctttctc tcgttgtgtc
     7021 ggtatgccga ttgcgtgctg gcgtctgtgt gtggaggtct ctgcgtggat tgagaacagg
     7081 tcgcaaaggt aggccgaacc cgccatcgat ccgacgctat tctacgcatt ctttacgtaa
     7141 ggccgactgg taatacccct ggaatcgcga gaaccggcga acgccgtcgc agatgttgct
     7201 gaggagacct gaaccatccc ttgtaggagt tcatccatcg gagtgatcga cctcagatac
     7261 gtcggggcgg acgccagcgc atctcagggt ctggattgct ccattgactc gattggtacg
     7321 caggagtagg gtttcatcgc tcttccgacc gacctttcac aggcttgagt aggtgaccgt
     7381 gcatgccgct ctgccagccg gatctttcat tattcaggag gaaatggcct atgtggagat
     7441 cacgtatagc aactgctgca ctcgccgtgg cgctgataag cccgctttca gtccttgcgg
     7501 aagaacctcc cgccaatcca aaatccctgg ccgagcagct cgtcgatgcc ttcaacgggg
     7561 tcttcggagt gcatccaggt atgcgggcca atcatccaaa agggatggtc ctggaaggca
     7621 cgttcacgcc caccgcatcg gcggcctccg tcagcaaggc ggctcacctg caaaagaaga
     7681 aaaccgctgt tccggtgacg gtgcggttct ctgccggttc ggggcaaccg tccgttccgg
     7741 acaccagcca gatgcctcgc gggatggccg tcaaattttc cctgcccgac ggatccaaga
     7801 cggatctcgt cgtcctttct tttaacggat ttcctgtggc cacggcggaa gagttcagag
     7861 actttctcct cgcggtcggg gcaagcggac ccgatgcccc taaacccact cccatcgagc
     7921 agttcctagc gacgcatccg gcggccaaac atttcgtgga gagcccgaag cctcaaccgg
     7981 tcagttatgc caccctgccc tatttcggca tcaacgcgtt caaattcacg aatgcgaaag
     8041 ggcacgtcac attcggtcga taccagcttc gccccatggc gggcgagcac tttctcaccc
     8101 aggaacaact caacacgatg gacccggatt atctgagcgc ggagattcgc gagagattgc
     8161 gccgtggccc tgccaagttc acgctcctcc tgcaagtggc ggaaaagggc gacaagatcg
     8221 acgatccctc gatcgcctgg ccggatagcc ggaaacagat caagttgggc acgatcagca
     8281 tcaccaaagc ggtggcggat agtcaggctg ccgagaagaa gctgcttttc atgccgggag
     8341 cgttggtccc cggtatcgaa gcagccgatc cgatgattgc cgctcgttcc gcctcgtatg
     8401 tcgtgtccct gtcacggcgg gcccaggcgc aatgaggctg gcgaaacact cgatggatcg
     8461 cggccctgtc ggaaatcggc gcgcagtact accagctaac gcaccgacgt ggtgatggca
     8521 cgctggtccc gggtatggct ggggcctgaa ggactgtggt tgatgatcag tctcgcggtg
     8581 tatgtcgccg ccgcaatgaa tcaaccgtcg acgccggcgg ggaacgactt ccttgaaacg
     8641 ctctgggtag ccattccatt agtcggcatt cccctcacct tcgcgacggc cttgttgcct
     8701 agaggctcag gctggtggtg gctgacccgt gtggtcgtcg cctcatgcat cggtgtgata
     8761 gtcgcttcct tcatcgcagc aggcggagtg gactatcacg attcccgcaa ctccggactc
     8821 ttgggcgcgc ccgtctacag cctctcgatc ggactgctgc tcctgtttcc cctcaccatt
     8881 ctcgctatcc tgctgatttg gaagaaacgc cgcacgagcc gctgattgcc ttagaattat
     8941 ggctacatga tgtttggatt atccacggga acgcgctagg gctccgccca gtagactaga
     9001 atcctgctgg cagtacgatt gcggtgagga gaacttgtga cggcatgacg ctgagcctcc
     9061 gattgggctg accctcagcg ctgcacgagc ctcagtgaac gaacggacct gccggtgaat
     9121 gggatagaca actcgatgac tctctccagg aaaacgattc acgacagtac cggcctgctt
     9181 ggagagttgc tggcgcagta tcacccccgg aattttgata tccgtttgtg ggacgggaca
     9241 atctggcctg ccgatcccgg cgcgactccc gaattcaccc tcatcctccg caccccaacc
     9301 gtcctgaggg acatgctgtg gaaggccagc gagctcgcac tagccgaggc gtttatctcc
     9361 ggtgatctgg agatcgatgg agatcttgaa caagccatcc ctcttgcgga atacctctcg
     9421 cgtcatcccg tgacctgggg gagttggctg cgattggggt tcaaatcatt acgttggcca
     9481 tcgaacccct ccttcaccac gaatggcctg gccgcacacg tcaccgggcc caaccattca
     9541 ctccttcgcg acaaacaagc catcgcgtat cattacgatc atcccccgga attttatgcc
     9601 gggtggttgg atccgcagat ggtctattca tgcgcctact tctctttcac cgacgatctc
     9661 gatgccgcgc aggtacacaa actcgattat ctctgcagaa agctccgtct ccgacgtggt
     9721 gagcggctgc tcgatgtcgg gtgcggctgg ggcgcactga tcgttcatgc tgcccgatac
     9781 tacggggtcc aggcctgcgg cattactttg agcgagaagc aggctgaatt tgcagaggcc
     9841 tgcattcaac aacatggact catggatcgc tgtcaggtcg aactccgcga ctatcgacaa
     9901 ctgagcactc ccaatcgcta tgacaagatt gtcagcgtcg gtatggtcga acatgtggga
     9961 gccactcacc tctcaggcta ttttcgccat atctggaatt tgctgaagcc gggcggaacc
    10021 tttctcaatc atgggatcgg gattcggcat ggggaacgct gcgccttcgg gccattcgtg
    10081 aatacctatg tcttccccga tgcggaattg accaccatct cgaccaccac cggattcgct
    10141 gaaaccgccg gctttgaagt aagagatgtg gagtgtttac gagagcatta cgtcctgacg
    10201 cttcgacaat ggagacagcg cctggagaag aacgtgacgc ccggatcgtc cagcatggat
    10261 gaatccacat ggagactgtg gcgcctgtat ctcgccagcg ccgcccatgg ctttgccaca
    10321 ggcaagctca acctctatca aaccttgctg tcgaaaacgc aggagggatc ggctggtctg
    10381 ccgttaacac gggatgactg gtacgaggcc cattcctcga ttgattcgcg cctgtcggga
    10441 agactgcgtt agtcccgtct ctgaataaga cttctttcct ccctcctcac attgttgctc
    10501 ttgagaagaa caccgcgtag ctcgaatgcg caaaatactt gctgcgtcca tgcaggaccg
    10561 ctagcctgac cttacaacac caacacgcgg ctgatcgggt tggtttggag aggaaagtca
    10621 tgaaacggga tacctggctt gtcgtgacgg cggtgactgg cggaatcgtc gtgtggttgt
    10681 tggtctcggc cttcgctcac aagagagagg cgtgggattc cgatctgtat ttcacgctgg
    10741 gcctgcccgc ggtctgcctg ctgtctgctc tgcttggcta ccttgaaccg aacagggcct
    10801 ggcgctgggg agcggcgcct cttgtcgggc aggcgcttgt gatgctgctg actcaaggcc
    10861 cgggtactgt gttgccgctc ggaatcatga tgttcggcgt ccttgcccta ccgtcgatcg
    10921 tcaccgcaaa gatgggagcc tatgcggcca agagaagccc gcacggatca accgctagac
    10981 agaaccattg agccgatcac cctgccgact cctggtcatc gtttctttcc agttcgcgcc
    11041 gcaatgcgtg actcagccga tacccagccg gcatcgaaag gatggccggc tgtatccaga
    11101 tcaatgacca gcggagcatg atccgaaggc aacggctttc ccttccgcgc ctcgcgatcg
    11161 atctctgacc aaatgacacg atctctcagc ggagtgctca cgagcaggtg atcgatgcgc
    11221 atgccgatgt tcttgtggaa attgccggcg cggtagtccc accacgtgta ccgccccggt
    11281 tccgggtggt ggcatcggta cgcatcgacg aatccctcgc gtacgatccg gtcgaatgca
    11341 cgccgctcac gatctgacac gtgcgtgccg ccgtggcagg cggccgggtc ccagacgtcg
    11401 atgtcctgag gcgccacgtt gaaatcgccc ccgatgacgc aggctttctg cggtgcaccc
    11461 gtctgcttga gccatcgcgc cagcttgtcg aaccagacca gcttcgcctc ataaaacgga
    11521 gaatcgacct cacggccatt cggtgcatac aggcagataa tgagcagtcc tccgcaatcg
    11581 gcagccaaca tcctggcttc ggcgaacggc tcgtcgtcgc ccgtgtcagt cgaacgtgcc
    11641 ggctgcaacg gctctccgaa attgctgatg acgccgctga tgccacagcg gctggcgatc
    11701 gcgacgccgt tccatcggcc ttcaccgtgg tgcgccagcg cgtatcccgc ctgtgcgaac
    11761 gcgtcgatcg gcgcatcggc atccgacaac ttcgtttcct gcatcagcaa cacgtcgggc
    11821 ttggcccgat ccagccacca caggaccttc tcgagacgcg ccttgagtga gttgacgttc
    11881 caggtcgcaa tccgcatccc ttacagtacc ctatttgaat ggacgtgtgc cgaagaaacg
    11941 gtcggtgggt cggtgggtgc ttggtcactg catgctgacg acaatccctt cgtcgggacc
    12001 gagaagaaaa tggtctgccg tccagggccc ttcggctctc agggggtcgg tggagagcat
    12061 caacgtgccg tgacgtccga gcttggaagg gccagccgga agtgagatct tctgcgtgtg
    12121 ggcgctgaag ttgacggcga taaacagagc gtctcgctgg ccatccacga ggctctctcg
    12181 tgtgaagaac aggcattccg gtggccctcc atcgacagga tgataggctc cgacggtgag
    12241 ggcgttcgat cctttcttca tccggataag ccgtttgtac agggacaaga tcgaagcggg
    12301 atcgcgctgc tccccagcca cattcgtctg ccgccatgcg tgtgaaagtg gcaaccaggg
    12361 tctgccggtc gtgaaaccgg cttgagggct gtcgtcccag ggcatgggag ttcgcgcggg
    12421 atcgcgtccg gttttccacg gccaatagcg gatggtgtag ggatcgtgca ggtccgctcg
    12481 cctgagcctg ccatcatgaa gacccaattc ttctccgtaa tagacgaatg gcgtaccgcg
    12541 aagcgtgaac aacagcaggg ctgcggccct ggcgcgccgg atagcctcgc cgcccgcgcc
    12601 gtaccgatcg atgtgccgcg actggtcatg gttgctgaac accaccggag gccagccacc
    12661 ctgtgggacc gcgcgatcgc tgtccaggat gagccggcga aaggtctccg gatgccagtt
    12721 ggaccgcagc aagcgaaagt cgaacacctc gtgcagttcg ttcgatccat tcccataaaa
    12781 tgccgcaggg cctccaggag tatccgagga cgtctccccg accagcagaa tatcctcgcg
    12841 atccttgagt gaggaccgga gtgcccgcag cgcctcgtgg gtatgcggct ggtcacggtc
    12901 gtagcgatgg atttgtcgat aatagctgcg ccacgccaga cggcgcggat tgtccggcca
    12961 actggtgtct ttccccaacc aattgatcgc atccaaccgg aagccgtcga ccccgcggtc
    13021 gagccagaac cggacgacac cgaagaccgc gtcgcggacg gcagggttgg tccagttcag
    13081 gtccggctgc tccgacaaaa acgaatgtaa gtagtactgg ccggtgtgcg gatcatgtgt
    13141 ccatgccgat ccaccgaatc gcgcagccca attattggga ggccgccggc cggatttgcc
    13201 gtcggcccag tagtaccagt cgcgtttcgc ggaggttctg gacgaacgcg attcgatgaa
    13261 ccagggatgc tggttcgacg tatggttcag gaccagatcc atgacgactc gtatgccccg
    13321 gcggtgagct tccgagacga ggcgatcgaa gtctgccagc gtgccgaagc gcggatcgat
    13381 atcgcagtag tcactgacgt cataaccgaa gtcatgcatg ggcgaaggat aaatcggaga
    13441 gagccagatg gcgtcgacgc cgagcgagtc tggcgacccg ttgagatagt cgagccggct
    13501 gatgatgccc ggaagatcgc cgattccatc cccgttcgaa tcctgaaagg accagggata
    13561 gatctgatag acgatggccg attgccacca gggagtgttg ggctgcagga gggtcatgat
    13621 ctgccttcga ccctacctca ggttgccccg aggtacaagc agagggcgaa aattgcaacg
    13681 acaggaccaa gacggaagcc gcgcggccac gaaggccacg ggaaatgtca ccggaagctc
    13741 gcgagatccg gcagccactt agcttcccag caatacgcct ctcgctgaga caatgacagt
    13801 gacactcagc cgacatgcgc tgaagaaacg ctgtgcgttc aacagagtac ccgtgatgaa
    13861 accagaaccg ccgatggtgg cgtaggtcgt caccgccgtt ggagcatcga ctctggaaat
    13921 cgtcccccga tctacctttt gcttcctctt cgcaccagtt ccttttttcc gcgtggcaga
    13981 tggaagtcac acatcaagcg gctgaagaag tctgcgcctt ccagccgagc gagctcatcc
    14041 gggaccgcca cttccttcaa cgactgtccc ttcatcggct cgatctgaat atgcaccggt
    14101 ttgcccttat gatcttttcc gggagtcagt aggcctcccc ccacgatcgc cccctttttg
    14161 ttcgtcagca catgcatggt ccgctttgct ttcacgtatg gcctcctttg gaacgcgtta
    14221 gacgtttccg ccaccctgaa tcgtaaaatg ggccagttcc tcgccgatgt tggtcacggt
    14281 caccgaatag acgacaggac ctgacggacc gggatgccgg cgaagggcct ttttttcttt
    14341 cgtgtgttcg ctgaccatga gacggaccgg gttgatcccg accccgtccg ccatgatcca
    14401 ctgggcgccg aagtcttccc ctccccactc ctcatcaggg accagcttcc cacgcgcgat
    14461 atgcacgcgg atggcttcac cgggcgccag ccagaaatct cccacttgat tgaatgccat
    14521 aacaggcctc ccttaaaaag ttcgggcgca ttatagcgaa cgagcacgcg cgatgtaatc
    14581 cagtcatcnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnta aaaagttcgg
    14701 gcgcattata gcgaacgagc acgcgcgatg taatccagtc atccgcgatt caacagtgga
    14761 attctttcca gcgggaactc acaatattgc cgaggaaggg tcaacccggg cagacgatga
    14821 cgacgatcga tcccaccaga catgaatggg cgaggtttga gcgcctcatt gtcttcgacg
    14881 gcatctgcaa ttggtgcaat gcctgggtta atttcacgat ggctcgtgac cgtgggcgct
    14941 ttcacttcgc gacgttgcaa tcggcgaagg ggcaggaact gctcacgctg ttgggattgc
    15001 ctgtccagga tttcgagacg tttctcctgc tggagcgggg tcaggtgttc accaaatcga
    15061 ccgccgcttt gagaatcgcc agaacgctgt ctggctggtg gccgttgctg tatggcttta
    15121 ttcttatacc ccgcggactg cgagatattc tgtacaacta cgtcgcacgc catcgctacc
    15181 ggcttatggg gaaggctgat acctgccgca tccccagcgc gacagaccgg gaccgtttcg
    15241 tctaagcgga ttgcccgccg atttttctga gtgcggtccc cttgtgcatc gccagatggc
    15301 ctgttttgtc gcttttcacg agatattgcg gctgctcctt ggaggctcgg gcgatatacg
    15361 acttgaactt catgggagcc gtgatccttt tctgaattgt ccctcgaata cgccccgctt
    15421 ccgaattcca actcacatga tcgcccactt taaaattttg atccatggca actcctccgg
    15481 ctggcgtgag tacgcattgt gccccctcgt tacgcatccc catactggga tggtgcccag
    15541 gtacgcctct cgccagcacg cccggtataa tgagccagtt gctttgaacc caggaggggt
    15601 ctcgacatgg atatcgtgtc gcacggtctg tggggagcgt tggcgtttgg tcgaagaagt
    15661 cgcacgagct tctggctggc gttcggaatc ggcctggcgc cggacctgtt ttcgttcggc
    15721 atcttgtggg cagctgcgac gcttggcctg tcgccgaagc ctgatttcag ccacggcacg
    15781 ccaccggagt ccaccattcc gccctacgtg catcatcttt acgatgtcac acatagcttc
    15841 gtcgtcttcc tcgccgtctt tgccctgttg tggcttgtca tgaaacgacc ggtgtgggag
    15901 cttggtgcct ggggtttaca tgtcttagtc gacatcccga cccattcgtt tgcgtttttt
    15961 ccaaccccca ttttctggcc tctctccgat tggaaattcg atgggtggca atggagccag
    16021 ccggccattc tcatcccgaa cttcacagtg ctgttgttgc tctacggttg gtttctgttc
    16081 caacaggcac ggccgattct caggcccgaa cgggcgcgtg actgacggtc cgtcccctac
    16141 gaagcgggca cccgcaggcc ctctggacca gcgcgagcta ccgccgtaca ctgatatcgt
    16201 tcagccatct ggataggtga gaggaaggag tgaacttatg gccaatagaa aacgcgagcc
    16261 ggtgccgacg ccccagtcca tcgcgtcgta tgtgaagcgg catgccccgc gagtgaaaca
    16321 aagccagcgg cggcatcatg ccgccactga gacgatccgc gaggcggacc atcaaggcca
    16381 ccacatcgtg gtgaagaccc ggtacgagat ttccgtcgac ggccgcaagg tgctcggtca
    16441 ccttggcgtc tccaacgacg ggcacgttca ttatcacccc atcccgaatt tgtcgttcgc
    16501 ctccgcgctg gacatggtga aagccatcat cgatgtgttc ccccaccagt tcgaggcgaa
    16561 gaaacgtccg cacaagggac cgggacgcat tcgccacacg aaccgaacac accactgagg
    16621 tgaactcatg gccgtgacca gacgcaacat tctcaccaat gccaacgttc gtgcgcagta
    16681 cgcccgcggg gtgaacctct tgaaacgtga gttcacgggt ccgacgacca gcagtctcgg
    16741 tatccccggt cccgctcgac agatcagcac ctatgattta ttcgtcgtct ggcaccatac
    16801 ggccatgtcg actatgacgc ctccgtcaca gggagaccgc aatgccgccc atcgcggccc
    16861 cgtgttcttc ccctggcacc ggttcatgtt gatcgagttg gaacgaaacc tccaacgagt
    16921 gctccgcgat gatacgttcg gacttcccta ctgggattgg gccgcggatg gatccaggac
    16981 accgggtcag cagcgacaat ctgcgctttg gcgggcatcg ggtgtcggcg gaacaggctc
    17041 accggttcgg accggtccct ttcgctttgt cgccgacgat cctgacagct ttcgcattcg
    17101 ggtcgaggct gatgcaaacg gccgactgat ccagagcaat cgcggcttgc ggcgggatct
    17161 gggggtgaat atcgcgaccc tccccactcg cactgatacg gccggcgccc ttgcgctcac
    17221 tctctacgat caacccaact gggatacaac atcggccggc tttcggaatc gagccgaagg
    17281 ctgggcagcg cctgacgcac cggcgctgca taaccgcgtg cacgtgtggg tcggcggaga
    17341 tatgttgccg tccagttccc ccaacgatcc cgtcttctat ctgaatcatt gcaatgaaga
    17401 ccgcctgtgg gaagcctgga tggcccggca tactcgcgcc tacgttccga cgcaatccgc
    17461 gcctgccagt ctccgcggac accgcctcaa cgaccagatg ctggcattcg tctctgcagc
    17521 aatgagaccc gctgacgtgc tcgacgtggg aagcatctac gtctacgatt ccctggccgt
    17581 atgaggggaa ggcctctttc gagaacccag ggagagccac atcttcccaa tggggccagc
    17641 agccctcagt cactcacacg cctgatcgaa ttgccaggag ccatggacca gtgcggtgca
    17701 accagctaca atgcgccggt ttcttcgggt cgctcttcct tttatctcgg agttcatcca
    17761 tggcagcgag ccagacgtat accgtcacca ttctgctgga cgtgaatgag gcgcaagacg
    17821 ttgacgatcg ggcggaaagt cgcagttatc tcgtagcgga tcacagctca agccaggccg
    17881 tgatcatcga tgccgtgctc gagaacatcg aacgcgatgt ccggatcctg aaggaactgg
    17941 gcctgacgct ggcctatgcg atcgaaaccc atgtgcatgc cgaccacatc accgccgcgt
    18001 cgctcctcaa ggatcgcacc ggcgcgcaaa ttgtctatgg tggtggcgca gccggaactg
    18061 tcatgggagc cgacctgttt ctttctgacg gacagacact ccggttcggc gggagtgcct
    18121 tgacggcgct ggcgacgccc ggtcacacgg acgggtgcac cagttatctc ttaccgggtg
    18181 cggtgtttac aggcgatgcg ctgttcattc gggggaatgg tcgaacggat ctccaagggg
    18241 gatcagcggc cacgctgttc gactcggttc gacagaaact gttcgcactg ccggacgaca
    18301 ccatcgtcta tccaggccac gactatcaag gccgggtcgc ttccaccatc ggcgaagaaa
    18361 aacgcttcaa tgaacggctc aatctctcaa tcgacaaaga cacgttcatc gagctgatga
    18421 acaggcggaa acaaccaagg cccgcgaaga tcgacattgc cgttccggcg aatctgcggg
    18481 ccggtcgcat ggcacgatga gcacgagccg cgtggtcgtc ggcgcgcgta cccacgcaga
    18541 caacggacga gcgcccgtct tgactgagag agcccaaccg aagagagtga ggatgcatgc
    18601 gccctgactg tacttctctc ccgaaacctg ttgcttccat tctgcttgcg gctctggcct
    18661 ggagcctcag ctcctgcgcg tcatcactag acatgtcaca cgaacagatc gcggcaccgg
    18721 gtcctgaatg gggaatcgtt atcgggtcgg tgctggtcag gcaagaacag aaaggctccg
    18781 gagccgacac ggcggtacgc gatcagtcca cgatgtttga ggttgaagtg gtgcaggttc
    18841 agcctggtga tcctaatggg gaaagtccct atgcagcccg atatcacgtg gacgccacgg
    18901 cgggcctgga ccggccgttt ctggcccggt tgcgacccgg acggtatctg atcaagaatt
    18961 tttatcgcac gggcatggcc ggcacgggag gcgacctcaa tctcgtcttc gaaagccaat
    19021 caggccgcgt ggtctatatc gggcaattgc ttgtcgaggt gccaccgcag ctgactcacg
    19081 ggaaagatta ccgcttttcg gtgcacgaca cccacgacat caccctctcc caacttgctc
    19141 cgcaccatcg cgatctgaca caacaggcca ccacggtccc catgcagatt cgcgagaaag
    19201 acagccactg agatatctga gcccaccaca cagcatctag aacgcctgcc ggcacagcct
    19261 gcagacttcc tgctctttca aatctccttc atttccttgt acattcaggg tcccacgcct
    19321 acactttcac ctatggaata cctagagtct tctcagacag accactgcat gacgaggctt
    19381 tcgttcgaaa gaaagttgga gctatgtcgc acaacctgaa actgtccctc tgtctgaacc
    19441 tgattctgct cggtttcatc cttaccggct acgtcggtcc cagcgtgaaa acgacattca
    19501 tgccggatgt cgaagcgccg gtgatcggga atcacaccag gattcatccc ctcggcattg
    19561 tcatcggatc cgtcaccctc ggcgatcgcg tgtttgtcgc gcccgccgcg tcggtgcgcg
    19621 gtgatgaggg gcggcacatc cacatcggaa acgagagcaa tgtgcaggac ggcgtcgtgg
    19681 ttcacggcct cgagaccttc gaaggcgacc atgaacttcc ggagaacgaa gtcgaagtcg
    19741 acggcatgaa gtattccgtc tacatcggca accgtgtgtc tcttgcgcat cagtcgcaag
    19801 tgcatggtcc cgctcgagtc ggcaatgata ccttcatcgg catgcaggcg ttggtgttcc
    19861 gtgcggaggt gggagatcgt gtcgtcgtcg aaccgggtgc caaaattatc ggggtgaagg
    19921 tgccttcagg acggtacgtg ccggcgctct cggttgtgac gacccaggat gtcgcggata
    19981 acctgccact gatcacggag cgctatccct atcgcaacct gaatgggggc gtggtccgcg
    20041 tcaatgtcca attggcagaa gccaggcaac cgcagcccat tgctcgctag gaagggacgc
    20101 ggcgcgcggc gccgtgaatt gagcatcaga tcaattcaac ggtcatcccg tcgactattc
    20161 gatcacgctg aactcgtaac gggagccgct caacgccgcc agtagctccg acgcatgttc
    20221 gcggccacgt gtttccatgg tcacgtccaa cgccgcctcg ttcagtccga caccataatg
    20281 ggcacggttg tacgatgtct ccacgatatt cgcgctggcc ttggcgatta cggaggtgag
    20341 tccttcaagc gaaccgggat agtccggcag cagcacgcgc agccgcaacc gccttccatc
    20401 cctgaccatc cctcgctcga tgatgcgggc cagaagattc acatccagat tcccgccgga
    20461 cacgagcacc gcgatgtttt tgccacggtg ccccgtatta ccctgtaaca atgccgccaa
    20521 ggccaccgcc cctgccccct ctgcaacggt cttctctcct tcgaggagcc tcaagatcgc
    20581 ggcggcgatt tcatcttcat cgacggtgac catctggtcg acgtagcgtt gcaccaacgg
    20641 cagcgtccgg gagcctgcgg ttctcaccgc gatcccgtcc gccagggtcg ggctggccgg
    20701 gagttcgacc ggaatgctgc tccccagcgc ggccttcatc gaggggagac gagctgtttg
    20761 cacgcccacc acttccacat tgctcgcctg ttccttcacc gcgcagccga cgcccccgat
    20821 cagccctccg cctcctaccg gcaccacgat cacatccaag gttggattct gccgcaacag
    20881 ttccaagccc agcgtcccct gtccggcgat cacctcgtcg tcatcgaagg gatggatgaa
    20941 ggtggcgtgc cgctcctcac ttcgctccat cgccgcccgg cacgcctcgt cgtaattctc
    21001 tccgtgcagc acgacatccg cgccatgatt ccgtgtcgcc gagagtttca ccaggggcgt
    21061 cgaccgcggc atccaaatct ggacaggaat gtttcgttgc accgcgtgat aggccacgcc
    21121 ctgggcgtgg ttgccggccg acgccgcgat gaccccgcgg cggcgctcct cctcggtcat
    21181 catgagaatc cgattgaggg cgccccgttc cttgaacgac cccgtcattt ggagattttc
    21241 gagcttgaga tagatcgtat tgccggtaag ccgggacaag gtcctggaat ggaccagggg
    21301 agattcgtag atggaagatg cgatgcgcga ggccgcggct gctatcgact gcactgtcac
    21361 catgccctgc tctcctttca ctgcctcaac tgattgcgat cacaaaaaag cccctgacgg
    21421 gagtgaatcc gccaggggcc tctgctgcat aggtacacgt ccggtggcag gcaggctcag
    21481 gcggagctgg cgatcatcat cgccgccgcc atgcgaatac caatgccctg ccgattgatg
    21541 gtcatgcttg atccgtcacg tcccgagaga cactcgatga gcggagcata taccagagcc
    21601 gggctaggat caagcacacc gtgaattcag gaagcgtcct ccccgatgac gccagccacc
    21661 cgactcagac cgggaccatc cactgagcaa ccgactgtgt cgttctgcga caggatgagc
    21721 cagtgatcgt ggacgagcct cgcgagaaaa agtagaatgg cctcgtccaa ctgattcccg
    21781 cgatatccaa tcactgccgc ctgctgatca tgccgtatcg aaggcagtga tcgtatgtct
    21841 tcatctctcg tggagagcac catgcaaaag acccgcatca tctgcacgat cggacctgcg
    21901 accgattcct atgagatgct gcagaagctc tatgacgccg gcatgagtat cgcccgtctc
    21961 aatatgtccc acggcgacca cgaatcgcac gctaaggtca tccagcacat caagagcctg
    22021 aacaggaaag tgaagtttcc catccccatt cttctggata cgcaaggccc ggagatccgc
    22081 accggagatc tctcgaatga attgaatctg cggcagggcg aaatcgtcag cgtgacgact
    22141 cgcgggccgt tgaacgtcga ggaaagctca atccacatca actatgccga cttgctcgac
    22201 gcggtcaacg tcggggaccg gatcaccgtc gacaacgggc tgattaattt cgaggtcctg
    22261 gagaagcatg aacgtcatat gcgctgccgc gtactcgacg gagggctgct gaagagcaaa
    22321 cgccacgtga atctcccggg cgtgcgcgtc aaccttccgg cgatcacacc aaaagacacg
    22381 aaggatattc tcttcggcct ggaacgggat gtggacttca tcgcgctttc cttcgtgcgg
    22441 gaggccggag atatccagca actgaaagcg ctcatgggcg acaaggtcgg ccgggtaaaa
    22501 atcatcgcca agatcgagga tcaggaagga gtcaagaatc tcgaatccat catcaaggaa
    22561 tcggacggca tcatggtcgc ccgcggagat ctgggcgtgg agatcaatct ggaagatttg
    22621 cccaatgtgc aacgcacgat cgtgcgactc tgcgccgagt acggcaagcg cgtgattgtg
    22681 gccacgcatc tcctcgaatc catgattcac catccgcatc ccactcgcgc cgaagtcacc
    22741 gatgtggcca atgcgatcta cgaagaggcc gatgccgtca tgctctccgg cgaaacgacc
    22801 gtgggaaaat acccggtgaa gtgcgtcgag tacctccgca ggattgcgct caagtctgaa
    22861 acgatcccgg gattacagtt tgccaaacgc ttgcgcgatg tcggcaacaa acagcagctg
    22921 gccgcagcgg ctgtgcaact ggcagagggt gtcaaggcca aaggcatcgt cgtgattacc
    22981 aggcgcggga tcatggccga tctcgtcgcc aactgccgcc cgtttgtcac gaacatctat
    23041 gcgttcacga acatgagcca gccccggcgg acgatgttgc tgaatcgcgg cgtctttccc
    23101 ttcaaaatcg acttcagttc agagcctgag aaaacgctcc aaacggcgtt ccggatcctc
    23161 aaggatcgtg aacgattcca ggccggagac aaggtcgtca ttatctcgga cgtcctggcg
    23221 cagcaacggg tggactcgat tcagattcgc gacgtaccgt cggacgacct tcctgtggac
    23281 gcgtgatggg ctagtcggga atttccgcct cgaccagttt cgtgagcagg gtcagcgatt
    23341 cctgccagcc aagataacag gcttccaccg gaatcatctc cggaatcccc tcctgcacgg
    23401 cggtcatctc ggtgccgcac gacacctgct tcaaggtaat cgtcacgtgc atctcaccag
    23461 gcagattcgg atcgtcgaac acatccgtgt agcggattcg ctcgtacggc gtgagttcca
    23521 gatatttccc gccgaaggag tggctctttc ccgtggtgaa gttcgtgaac gacatcttga
    23581 aggttccgcc caccttggcg tccatatgat gcacgtttcc ggtgaacccg tttggtggca
    23641 gccatttggc catggcgtcc gcatcaagaa aggcacggta tattcgttcc ggcgtcgagc
    23701 gaagtactcg gtgaagacgg acggtattgg tcggcatggt ccgggctcct ttcaaaggaa
    23761 gagcctctcg gtcggcgaga agcatgatta gcgatcgcgc tatgcaggat gccaggagtc
    23821 acgcattttt gtctagacga gatctcggca taagcacgca tggaacaagc gcccgtggtc
    23881 tgttacagta aacgacaagg catcagctcg cttcacggtc atcgagagga agcagagcaa
    23941 cggggatgac gataccgggc agctgggcta tcgctaacat ggaccgcctg cattgaaaag
    24001 gaaggcatca tgaacgttcg gcatcgttca atcactcacg catgtgcgtc gatcactctg
    24061 acctgtggtc tcgtcctcgt gagcctcacc ggctccggct gtcagaccgc gtattacgaa
    24121 acgatggaaa agctgggcta tcacaaacgt gacctgatgg tcagtgatgt gaaaaaagcc
    24181 cgcgatgccc agcaggacgc gaaggaacaa ttcaaatcgg cgctcgatcg cttcacgaaa
    24241 acgttgaata tccaaggcgg tgagttgcag gacaagtacg aggtgttgaa cagcgaatac
    24301 cagcagagcg aaaaacgcgc ggaagccgtt cgcagccgca tcgcttcagt ggaggatgtg
    24361 tcggacgccc tcttcacgga gtgggagggg gaactgaagc agtattcgaa cgcatcgctg
    24421 cgtcagaaaa gccagaagca gctcgcgcag acgcgcaccc agtacgggca attgatcaag
    24481 gccatgaaac gcgcggaggc caagatggat cccgtgttgg ccaaactcaa ggaccatgtc
    24541 ctgttcttga agcacaacct caatgcgcag gccatcgcct cgctgaagag tgaattgacc
    24601 acggtcgaag gcaacatcga cttgctgatc aaggatctca acgcgtcgat ccacgaagcg
    24661 gataccttta ttgcctccat ggaaaaagag aacgcctgat cgcgagccac ccaccggccg
    24721 cacattttcg atcattcctg gcagccaatg agatctgcgc ggccggcggt tcagcaatga
    24781 accagctagg caagcgcggg gtcagactgg gtcggcttac gacgacgcct ggcagcagcg
    24841 agccgcgctc caaggaggct catgccaaag gccgtgccca cgaaaacagg ccacacgaga
    24901 gatttcatcc agcctgagct cgacatggtc gccggccaca gccaggccac ccagggtaac
    24961 gccgatccca caagagaaca ggccgcatga accggaggaa gccggaaaaa ccacgcgaga
    25021 agcgcgcccg agagcgcata tgcgggaggc accagcagca ggagaaagaa cacgccgttg
    25081 aacatggctg cgaaactgag gaaaaaccat aggaagccga cgagaaaccc ggcaaagagg
    25141 ccgcctcccg ttcctctgct ccgctgatgt tgttgatcca tggtcccagt gtatcccgtg
    25201 accaccagcg caccaaggaa ttttaggttc ggcgtctact tagctgcgga tgccgcctga
    25261 gtatctcgcc cagcccgcgc cttcgatgct tcaagctccg gcaacggctg cccgacgaga
    25321 ccctggagat accccttatc gaccgcgtcg aacagagcct ggcgcgctgc cccctccggt
    25381 ccttcgacgg cgatcaccac attgtgcacg gcgaggcctc cgctacggcg ggcgctcggc
    25441 gcgccgaatg tcgctatcgt agggcctggc tcagggaatc gttccatgtt catcgcgagg
    25501 cgcaccgcca gatcctgcgg ataggattcc aaccgcttag cttgggcgcg cagtgggtcg
    25561 gtttgagatt tgaccgacgc gacatggtcg ctgagcagct tcttcgccgc gtcttcgagt
    25621 ttctttccct cagccatggc acgagtcact tgctcctgtt gctcgggcgt gaagggtggg
    25681 tccttccggc tgcgacgtgg cgcggcatcg taggcagcct tcatctgcgc gagtacctgc
    25741 ttatattccg cgtccttctc cggcggcaat ttctccgcct cttcaatctg cttctcaacc
    25801 gccttgcgtt cggcgtacaa ccgatcggcc tccgccttgg gaaatttgta cagatacccc
    25861 ccgctcacat tgggaatgaa cgcccctacc tggttggatg tacaaaacga gaggcgcggt
    25921 tgccgggaaa aatcataggt tcccccgcgc cgttcgctat tggcaatggg agatggtaat
    25981 gccgccgcca gtgctgcttc cgcgcgagct gcgaacgcca gttcttccga tgtcggatca
    26041 cggaccccgt ccacgcaatc cgcgcggacc accgccggca tgacaccaat gaccatcgcg
    26101 agcatgaata ccgcagcaag cccaacccat gtcctacgca ttgcagccct cccactctga
    26161 gtgccaatag caattcccag ccaatacgac ctgagtatag gcaatgggtg aacgaagtca
    26221 acgtgtacaa ggtcgccggc gtacagaatt cttgcgggaa tctacctgtt tgactaagat
    26281 ccatccatga cgacacaggc ctcgccttct tctgacgacc aatctgacac accgacgcct
    26341 catcgctcac ccgatcccgc ccccgacggg ccacggccgg cagcaacaga gctcgatcgc
    26401 tttttcgagc tgtctttaga catgctctgc attgcgaacg cggacagcta tttcacacgc
    26461 ctgagtcccg catttacccg caccctaggc tggagtctcg aagaattgat gagccgaccg
    26521 ttccttgatt tcgtccatcc cgacgatcgg gccatgaccc tcctcgaggt cgagcgccag
    26581 atcggccggg gtgagccggt cctggaattt caaaaccgct atcagcacaa gaacggttca
    26641 tggcggctgc tgtcgtggaa gtcttcgccg catccggatg gacgcatgta tgcgattgca
    26701 cgcgacgtca cggaccgcga gcaggcacag caggcgttac gacgctccca tgaggaattg
    26761 gagcaccgcg ttcaggaacg gacggcggaa ctccagcagc gcaatcgcga tttggaaacg
    26821 ctgctctatg tcagctctca cgatctgcgt gagcccctgc gatcaatttc aaacttctcg
    26881 caactggtgc gagaccggta cggagatcgt ctggacgcga agggcctcga ttacatcgat
    26941 cgcgtcgttc gcgcggcgca acgcatggat cagctgatgg aggatctcct cacgctgtcg
    27001 agggcccaac gattagagat gccctacgaa gacgtccctg gcgaagacgt ggtcaaagcc
    27061 gccttgacgc aactggatga gacgattcga cgcaccgggg cacgtgtcca ggtagccgcg
    27121 aactttccct ggtttcgcgt caataaaacg tggatcacgc aagcgctgta caacctcatt
    27181 gcgaacgcgc tgaagtttca cctggccggg aaagtccccg agattgagat cgcccctttc
    27241 tatctgacgg aagagacggt cccgctggca gggattgtgg tgcgcgaccg tggtatcggg
    27301 gttgagccgg atcaggcgca gcggatcttt caattgtttc aacgggcagt gggacgcgaa
    27361 gtgagcggca ccggcgcggg cctggccatc gttcagcaaa tcgcacatcg gcacggcggg
    27421 cgcgcgtggg tgcaaccgcg ggaaggcggc ggatcggaat tcgtgctgct cttcggaagc
    27481 caatcagtca tcggcaagaa accggcatcc tgatttcacc gctcctcagt tcgaccgtta
    27541 actcaattgc ctggggcggc ccggacagca gatgcccccg taccacatcc gaccgataca
    27601 ggttccgccc tggagggagc ccgctgccgt agaacggcaa ccggctccct cctctctcga
    27661 gaccgctgaa attcacaccg gcttcatcgt atgtggctaa ctacccacac cacccggtcc
    27721 ttcactcagt gacccggctc gcccgcaagt cgcccggttg ggtgggcagc agcatgatgc
    27781 agttgggatt aaatccctga gccttcagcg tgtcgatatt ccccaggatt gtatctgcct
    27841 tgagatcgat cacggtaatc gagccatcgc tcatcccgtc caggttgaga aagctgttct
    27901 ggacgaacag gtagcgctcg tccggcgaca gcacgctatg gtgtgcgccg gcggccgcgg
    27961 cgatcgtttt gagaaacttc ggttgccccg ggtcgctgtt gtcgtacaga ttgacgaaac
    28021 ccggtttcgc cgtggtgacg aagagacgat ctcccttggc gttgtagagc atttcgagcg
    28081 gcatgccctg ctgccgtggg ccgaagtcat cgacctgatg gaacgaaaac gtcttgctgg
    28141 ccggatccca gaggccggcc cacaatgtcc cttcgagcat attggtgata tgcacggcgg
    28201 gaggattcga attcggactg aacatgactt cgacgggagc ggctttcgcc ggtgacggtt
    28261 tcgctgagac cttgtgggtc gagagcacgc ggccgctacc ggcctccatc acggtgatgg
    28321 agtctcccgc atcggacatg tccggtttga cggtactggt cacaaggacg cgatcgatgc
    28381 cgttatgaat cgcaatcccg tgtggatact gaattgtggc caacgccggc tctgctgcgc
    28441 tgaccgtttt gatcggctta tcgagcaagg catctcccat aatgacattg ttcgagccca
    28501 tgcaggtgag ataccaggtt cggttatcct ctgacacggc cagatcttct cccatctgac
    28561 aatccggcac gtcgatcgcc ctcagccgat aagggaattc tgtgagattc acgacgtgca
    28621 gaatgctctt ccccaaggcc gtgacgtagg ctttactccg gtcgcgattg aagaagatat
    28681 ggtgggcgac gagatcggga ggcagcggaa tctccatcag gattttcccg aagttcccgg
    28741 attcgggatc gatgtccata atggcaatgc cttcccgtct taccgtttgg tccggcttgc
    28801 tctcataatt gagcaacgcc agtatttccg ctgaagccag cgtgttgcag gccagcaata
    28861 accccagcgt gaggatgaat gatcgataga gtttcatgat gagctccttt tcaattgcgg
    28921 cagcgaactc acggtgcctt cttccagtgg tggcggctcc gacatcgttg tccgcgcgat
    28981 aggcctctat tgcagggcgg gccgacagtc ccggcccgcc tcaccggtta gatccccttc
    29041 agcgcatggg tgccgtgcgt gacggcaccg ccggcgcgca acgcggctgt cacgagaacc
    29101 gattcagcaa tctcggcggc cgaggcgcca tattctttcg ccttgttcgc gtgcagttcg
    29161 atgcagtagg gacattgcgt ggtgaacgcc acggccaggg ccatcaactc cttgtacttc
    29221 cctgggatcg cgccgggcgc cagtgcagcc ttatcgaagg ccacgaacgc cttcatcgcc
    29281 tcgggtgcat gcgcccccag atctttcacc ctccccaaat tcgtcatgtc atacagaccc
    29341 gtcgtctgat cgatctcggt ggtggtcgcg ttcgtcatga tgcatctcct ttgtatgggc
    29401 aatcggggtt tacgaccgaa tgccgatgac ttccaaatat tcgccataca ccgtcgtgca
    29461 gtccggtccc gcttgattgt gcgcggccca cagcgtttcc agatcccggc gcaaatgcgc
    29521 ctgcccttcg gcctcaaggg aggcaaaggc ccggttggtc ggtccatagt agagacggaa
    29581 aaattccacg acctccgagg gaggaaacgg atagctgaag agatactgcc gtctggtcag
    29641 gctgattgtg gacaatccgt gaccgaggcg ttcctgcacc gtggcttcgt taccccacag
    29701 caccggcgac ggcattcccg acgggccgat gaatttcgcg acgttcttaa acatctggcc
    29761 cacaaacccc tccgccgtcc aattggccat ggcaagggtc ccaccgggcg tgcacacccg
    29821 caataactcc tgcgccacca ggtcaggccg cggggcgaac atcgcaccga tcaggctcgt
    29881 cacggcatca aaactggctg tttcatacgg aagcgcttcg gcatcggcga cttcgaatcg
    29941 tgctgacacc ccttccgcgc gcgccctggc ttgcgcgcgc tcgacccaat tggccgcaat
    30001 gtccactccc gtcacctcca ggccatcctt cgcggcgatc aacgccagtt ggcccgaccc
    30061 gcacccgaca tccagcaacc ggcaccccgg cgcaatctgc aggcgttcgt aaaactccct
    30121 ggcgccgccc tccatgtatc gtgaaaatcg atcgtagtct cctgccgtcc aaatagtatt
    30181 gagacgggtc ttcagactat cgagctccgg cattatggta ttcgtcgtca tggcctcctc
    30241 cttgttgaat gtgctctgtc ctcgtgcctc gtaccgcgcg ctgtctggtt gcactatagg
    30301 acaggggccg ttccgcgtct tatccgcacg tctggctctc ttatcgggag catgctaagc
    30361 tgcagatcgt ttatccgggc gtccggatga ctttgctcag actccggcct cgccgaggaa
    30421 ctgttcatgg acgtgctgtc cgaagtgctg aaggccgtga aactcgacgg tgccgtgttc
    30481 tttcacggtg aattcgccgc gccctggtgc gcacaagaac ctgacgccga gaccatggcg
    30541 tcgtatctcc ccacccaagc cggccacatc atcatttttc atctgctgct ggaaggacgg
    30601 ggctatattc gcctcgggga cgaggaccgc gcggtgccgc tgacggcggg agacatcatc
    30661 attctcacgc agggggatgc gcactatatg ggcaacgggc cgcccgtcac gccggtggac
    30721 acctctctgc aaatccgtca gatcctcgcg gagggacgta tgatgtcgca actcgccggc
    30781 ggcggggaaa ttacgaagct gatctgcggg tacctgacgt gcgacgcgca gctatgccgg
    30841 gttgtcctgg ccgggctgcc cgccatgctg aaggtgaata tccgggatac gccgtcggga
    30901 cactggctgg agaatacgct ccgctactcc gtcgatcacg cagaggcatc cggtcccgga
    30961 ggcgcagcgg tgatcgcgaa gttatccgaa gccttgttcg tggagacgtt gcgacgctac
    31021 atcgcacaat tgccgcacac cgagaccggc tggcttgccg gggtgcgtga tccggacgtg
    31081 ggcaaagctt tggcgctcct gcatcaacgc cccgcccaac catggaccat cgccacgctc
    31141 gccgccgagg tcggtgtgtc ccggtccgtg ctggctgaac ggtttcagca tttcctcgcc
    31201 gacacaccga tcggctatct cacccgctgg cggctgcacc tcgccgcgca actgctcacg
    31261 tccacgtcca agagcgtggc cgaagtcgcc ggcgacatcg gctatgagtc agaaccctct
    31321 ttcaaccgcg ccttcaaacg ggagttcaat ctgcctccgg caagatttcg tgcccaatcg
    31381 aaggcgtcgt tggctggaaa cggtgccgtc tcccggcaag atcaccgatc agcgcctgcc
    31441 aggtgaacct ccggcccttc gaatcggcct tccatcgcct tgcacttggt ccacgggtgt
    31501 gctgccgcgc cggcgaccgc tcccaccatg gcaaacggca tcgcgacaac aaagagcggc
    31561 acaccgatac catacccgag ccattgcatc gcgatgctct tgcgcttctg tcccgcctcg
    31621 acgacctgtt cggctggata caacggaaag gtgccgtatt cgctgcccag gctcgcactt
    31681 tcgccgatcg tccggcagcg cgcctcactc atcaccggca gcaagagact catgcagaca
    31741 cagagcacta tcgttttcat caccactccc tccagtaaac accaccgcaa ttggctgctc
    31801 gcccgggtgc gaaaagatac cagcacatcc catgcctgtc gttgatacca acgaaacgct
    31861 gggttctatt tgagcggtta catctccccg cgaaaccgag cgctttcgcg cattcggcag
    31921 cgtgcgaaaa cacaggctgc aataaatacg caatccgtcc tcataccact gtctcaacat
    31981 gaggcaaaaa aaatccttgc ttctgtagga caaccggcgt attagtccta gtacagttga
    32041 tcctgactag aacgattcac tgcggctcca tcgcaccatg aggattcgat cctcttggtg
    32101 aatcaatacg gtttcccggc ccattgaatg agtgctcaac gcacctgcca tgatgcgaat
    32161 catggatccc tgggctctgc atttctctca tacgttccgg acacgatgtt ccccggcgct
    32221 gcactttcgg cgcaggaagg aggagccatt gctattccat acatcggcct ctggtatcga
    32281 acagccatcc gcgcttcaag ctgataccgc cctctctgct cgcctgcttg tctcgtggct
    32341 ggtgttctgg attctcgccc tcccgctcat gcacgtgcac attcaagctg agcggcatca
    32401 ggggcttccg cacaatgtgc tggccggcga tctgccgggt gagtttgtct cgtccgcaga
    32461 tagcgccata gaagcggcgc aacccgctgg cgttccgcct cctccacacc tcgcctccgg
    32521 tatttcctat ccggaattgg cgttcactgc gccggttcct tccaaacatc attggttgtt
    32581 ttctctgacc gccattttca cacgtgacat tccagcagag atgtttccca ccggtagaac
    32641 ggttactccc gaccaacgtt cattcgatca ccccactcca ctccctctat cctctccacg
    32701 cgcgccgccg ccagtcgacc ggctgaccta agatcattcg cgctgaagag agtgattctg
    32761 gagaacatgc tccaaaggga tccgtctgtt caaaagatgg atgggagacg actggcattc
    32821 gcacgaccaa taggagattc agcatgaaat tatttgcttt ggcagtggtg agctcgacga
    32881 cattgctctt gggctccacg ggcaccgcct tcagtgccgg tgcatcttca gatagcaaca
    32941 gcgtgaagga ggcatctcct tccgcgcaac tgattctcgc caagcagggc cg
//
LOCUS       DAOQPD010000041        32905 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_591_length_32905_cov_19.944292, whole genome shotgun sequence.
ACCESSION   DAOQPD010000041 DAOQPD010000000
VERSION     DAOQPD010000041.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 32905)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 32905)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32905
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_591_length_32905_cov_19.944292"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..961)
                     /locus_tag="PK063_10845"
     CDS             complement(<1..961)
                     /locus_tag="PK063_10845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HMZ97594.1"
                     /translation="MYPSNRHSIETLLKTPIGRRTALALGARAASLLATTMGLGAATG
                     LLQSLGGCQRAPGTARDQFIYLSEEKEMAMGLSAFREVLRQAPLSDNPELNEMVHRVG
                     NRIAKAANKPEYQWEFAVIQDDRTINAFALPGGKVAVFTGILKVTKTEDGLATVMGHE
                     VAHALQRHGAERMSRGILEQIGQLAALGAGAAVGRPDAAMAAMTVYGVGVSLPFDRRQ
                     ESEADFIGLRLMAEAGYDPREAVSFWERMSGCPRAMINKLCFRSQQAIPEFLSTHPSD
                     VTRINQIEAWIPDAMKHYHPAGKAPAIPSGPIQPYRPPVGPMPE"
     gene            complement(1012..2001)
                     /gene="sppA"
                     /locus_tag="PK063_10850"
     CDS             complement(1012..2001)
                     /gene="sppA"
                     /locus_tag="PK063_10850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HMZ97595.1"
                     /translation="MKRNVGQAPDVWQLSTGLLVLALALMQAACVTINLPPGPGALEE
                     HKVSGTGKDKVLLMDVSGVISSENKDGFYSSPGMLATVKEELERAAKDERVKAIVLRI
                     NSPGGTVTASDIIYHELRNFKTSRKIPIVASIMDVGASGGYYIAAAADTVLAHPSSVT
                     GSIGVIMLTVNARGLLEKVGVETNAVTSGPRKDMGSPFRAMLPEERAIFQGVIDGFYQ
                     RFLQVVQEGRPGMNGETIKKLADGRIYSGEQAKAAGLVDDIGYLDDAIELAKKKAGLT
                     DAKVVTYRRPGEYQNNVYSRLVAPAPSLASLANVDLLSVVRGGSPQFMYLWMP"
     gene            complement(2159..3343)
                     /gene="carA"
                     /locus_tag="PK063_10855"
     CDS             complement(2159..3343)
                     /gene="carA"
                     /locus_tag="PK063_10855"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005951 - carbamoyl-phosphate synthase
                     complex [Evidence IEA];
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HMZ97596.1"
                     /translation="MKKAILALADGTWFEGRALGAEGETGGEVVFNTAMTGYQEVLTD
                     PSYRGQIVTMTSPQIGNYGVTPEDVESTKIWAEGFIVKESSRLASNWRGKSTLQEYLQ
                     AAHIVAIEGIDTRALTRHLRERGAQPGVISHIDLDPRRVAEKARQAPSIIGRDLAATV
                     TCEHRYPWTEGTGDWAPKITMPEQGAAKAPRKTWRVVAYDFGVKQNILRRLVDVGCEV
                     TVVPASTPAKDVLALNPQGLFLSNGPGDPEGVPYAMTALRELIGRVPIFGICLGHQLL
                     GLALGFSTYKLKFGHHGANHPVIDLRTRKVEITSQNHNFAVRFPGETPVVGQELPIVD
                     TPFGRVQLTHTSLNDASVEGMRCLDRPVFSVQYHPEASPGPHDSAYLFEQFVALMETH
                     HA"
     gene            complement(3346..3855)
                     /locus_tag="PK063_10860"
     CDS             complement(3346..3855)
                     /locus_tag="PK063_10860"
                     /inference="COORDINATES: protein motif:HMM:NF025046.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4149 domain-containing protein"
                     /protein_id="HMZ97597.1"
                     /translation="MRQGLIACVTFEMLALAVWIGGLLVLVAAVIPAVFNTFGGQDTG
                     GFFLTRAFDGYNRLVLGAAAILIAGILWRAWLYQQGMTDEAITRAEWLLLGAMLLIAG
                     VITFVLHPQAAALQAQAFASKGEDARKAAFEAFFQLHKPVRVLYILNVGLGIALLTLR
                     VRSWIRVKE"
     gene            complement(3868..5157)
                     /locus_tag="PK063_10865"
     CDS             complement(3868..5157)
                     /locus_tag="PK063_10865"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HMZ97598.1"
                     /translation="MILIKGGHVIDPGRVNGIADVLIENGKIAAVGQKLAAPAGATVI
                     QAGGQLVLPGFVDLHVHFREPGFEYKETIQSGTDAAVAGGFTTVCAMPNTNPVNDNQA
                     VTEFMLERAKAAGTANLYPIGAITKRSEGKELAEIGDLRRAGCVAISDDGKPVMNSLV
                     MRRAMEYARAFDVPVVDHCEDLHLSEGGCMNEGLISTELGLPGIPSAAEDVMVARNVS
                     LAELTGARLHLAHISTAGSVRMVREAKARGLKVTAEACPHHFTLTEETTRGYNTHAKM
                     NPPLRTSQDVQAIKDGLRDGTIDVIATDHAPHASQEKQQEFTEAPFGIVGLETALPLT
                     LTLVEEGVLTLESAVDKLATAPAKAFSLNAGTLAVGAPADVAIVDPNLEWEVDPSRFR
                     SKSRNTPFAGWKVKGRVTTTLVSGRVVYELDRPGRQA"
     gene            complement(5247..6170)
                     /locus_tag="PK063_10870"
     CDS             complement(5247..6170)
                     /locus_tag="PK063_10870"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HMZ97599.1"
                     /translation="MGLKRKDLLSLTNLSAADIALILDTADSFKEVSGREIKKVPALR
                     GKTVVNLFFEPSTRTRTSFELAAKRLSADVINFSPSSSSVVKGETLLDTARNIEAMQA
                     DIIVLRHSSAGAAETLARGVKSSVINAGDGWHEHPTQALLDLYTIRSRGMGFSGLKVA
                     IVGDVAHSRVARSNIFALTKLGAEVRVVGPPTMIPLHINQLGAQVYYNLDEGLRGVHV
                     IMMLRLQLERQGRALFPTIREYARQYGLTNERVKLAEPGAIVMHPGPINRGVEIAPDV
                     ADSLSSVILDQVANGVAVRMGILYLMSGANA"
     gene            complement(6185..6769)
                     /gene="pyrR"
                     /locus_tag="PK063_10875"
     CDS             complement(6185..6769)
                     /gene="pyrR"
                     /locus_tag="PK063_10875"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HMZ97600.1"
                     /translation="MPPADRPLMTTESTTGNRQERVVMDAGDIARAVTRIAHEILERN
                     KGIQDLALVGIRTGGVHLAHRLVRRIHDIEGTQIPIGELDITLYRDDLSLRKDQPILR
                     TTSVPFKISDLKVVLVDDVLFTGRTIRAAMDGLMDLGRPAEIQLAVLVDRGHRQLPIK
                     ANYIGKNIPTSRDEAIEVHLEENGEEDRVVILRT"
     gene            7078..8964
                     /locus_tag="PK063_10880"
     CDS             7078..8964
                     /locus_tag="PK063_10880"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HMZ97601.1"
                     /translation="MTSPSGSTTTPDLLTALANTATNLRIDSVKATSEAGSGHPSSCC
                     SAADILAVLFFSVMRYDPKNPKLPNSDRFVLSKGHAAPLLYAAWAEAGLFPKSELLKL
                     RTLGSDLEGHPTPRLSFVDMATGSLGQGLPAGVGLAFNAKSIDKTDYRTYVLMGDGES
                     VEGSVWEAAEVARQAKLDNLCAIVDVNRLGQSDPTMLQHDMDAYRARWSGFGWHAIVV
                     DGHDISALVAAFAEAAKTKGQPTVLLAKTFKGRGISFMENHPDWHGKPLKKGEETQKA
                     LDELTGQLKPSSTRLQISLPTAAKTAPSTKGTLAPAPYKVGDSVATREAFGAALLALG
                     EANSQVVALDADVKNSTYSDKFGKRFPDRFLENFIAEQNMLGAAAGIAACGKIPFVAT
                     FAAFFTRAYDFIRMAAISQSNIKLVGTHVGVSIGEDGPSQMGLEDLAMMSTQPGVTVL
                     YPSDGLSMYKLMESATAHKGMVYLRAGRPKTPVIYSADETFKIGGSKILRQSAADQLT
                     IVAAGVTLFEALKAHDQLKAAGIATRVVDLYSIVPVDQATLIDCARATGGRFLTVEDH
                     YAHGGIGDAVLSALASEGVRVRKLAVRDIPRSGKPDELVDHFGIGVRSIVEAAKEIAT
                     AARR"
     gene            8921..9661
                     /locus_tag="PK063_10885"
     CDS             8921..9661
                     /locus_tag="PK063_10885"
                     /inference="COORDINATES: protein motif:HMM:NF012257.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HMZ97602.1"
                     /translation="MSKQPKRSPQQPAAERPSPGAPAGLNQIPLLQILSAQDRQKVLG
                     EMTETRYGKGDYIFREGDPTEYFHIVKEGSVKCVKSSLDGKECTLKVLMPGDLFCCDA
                     SAFDGASHPGTAQPMGDVSVLRMKKEAYFKMLRANPDAAMEVIRYLGNRLNEAQEKAK
                     VLALDRADQRLASLLVSLAERSGIKDPNGIRVTVRLTRQDMANMVGVTTETAIRIMAR
                     FKKDRLVTGTAARLVIRDLPKLKLLAST"
     gene            9834..10799
                     /locus_tag="PK063_10890"
     CDS             9834..10799
                     /locus_tag="PK063_10890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multicopper oxidase domain-containing protein"
                     /protein_id="HMZ97603.1"
                     /translation="MYTHTDHRGGRTGKTIMFIGVMLSMLAGMALSAQAKTHDIKMTA
                     VETDIVIDGGGEKYAAWTFNGQFPGPVVRVTEGDTINFTLTNPATNKNPHAMDFHAAE
                     IDFLKNYRAVNTGESISFTFVAKKPGLFFYHCGAPPMIQHVARGMFGAIIVDPKNAKV
                     WPKADREYVLVQSEYYKNPNDVQAMFDRKYDGMMFNGGIFKYHPFVTGGGKLDAKPGE
                     RVRIYFVNAGPNEFSSFHPIGEIWDNVYESGNPANNLKGVQTYVVGPGSAATFDVVVE
                     SAGAYPLVTHSLTGALRGAIAVLLAGPDAKPAPLMPMVPWEIPAK"
     gene            10912..11259
                     /locus_tag="PK063_10895"
     CDS             10912..11259
                     /locus_tag="PK063_10895"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97604.1"
                     /translation="MRCPGMTLSCLLLFAGCLVSPASADTSRERVALFLSGQDCPSSR
                     RNIAAELAQVAGVIRVDMESVPDHALVDVVIGAVSPDDLLVAVHRSALKGVDCRAEVM
                     KSCISAGRSAADR"
     gene            11321..11950
                     /locus_tag="PK063_10900"
     CDS             11321..11950
                     /locus_tag="PK063_10900"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97605.1"
                     /translation="MRTTVLKGQRGIAWPFWLAVMATVWLLPVAPVVAQEAVLEFPIR
                     PFNVDVMLRQQTFAPDDREIGVQLGITAVRYGNVEVRTIYQFFSIHTQDFSTDQHSLF
                     VNPRWNNFIDILDFPKHKPISRIIRHVLFGPLEDRAVPYVGVLAGGVLPGPGNRAPGH
                     LIGGQVGVRFPVAQSLSVDISVQYSQYGVDFRGDAGQAQQWVFLTGIRF"
     gene            11920..12981
                     /locus_tag="PK063_10905"
     CDS             11920..12981
                     /locus_tag="PK063_10905"
                     /inference="COORDINATES: protein motif:HMM:NF012707.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HMZ97606.1"
                     /translation="MGIPDRDTVLIKATWCGRIWAALCCLLLSGCGLLIDAVEQVWPV
                     AGSKVDIICERGRVQVGLAMEPFRPFVFPTIWTDEGARVTGLDVELTRAMTDELSRRC
                     GHPVTPVLHLVRFRDLFRLLNEGHLDWFVSAVATNTPAPSRAGVAYSLPYFYGGGISG
                     ITTSTSVLERVRENLQQQATHPAADRLAATSHALDGLTIAVQDETSAYYYAEANWGAN
                     RLIVCDSLPAAFEYADAKTEPRVDIILGAQPVLEYMVKRVRKDWSLLTRENGRPLFLT
                     KADYGVVVAEESYRLRWLVNDLLLKLDESGRLGEMRTRWLDDEYAFPRRASLEGLPFD
                     VEKMASHYIQGTCRIRPGS"
     gene            13004..13762
                     /locus_tag="PK063_10910"
     CDS             13004..13762
                     /locus_tag="PK063_10910"
                     /inference="COORDINATES: protein motif:HMM:NF023273.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3365 domain-containing protein"
                     /protein_id="HMZ97607.1"
                     /translation="MRRRAWIALAAVMLLMCLHPSMSVAVERAEAEETARLLAKLLES
                     GRAVIERNQSLIDDPHKGEKGFTPELFEQQLIREFHAKTGIDLNALPAAPVSLRIPPL
                     AKELLPALVQASREVVRDAQVVINQRGIGYKNFIPATYGSQASARFSKAAHVRLKQTT
                     IQPRNPKNEPDEYEASVLKWLSARPRAEAYVSELTDGGRTLRVVMPIYYAKDCLACHG
                     EPKGDLDISGYPKEGHQEGDLAGAITVTAPLGNR"
     gene            complement(13765..14082)
                     /locus_tag="PK063_10915"
     CDS             complement(13765..14082)
                     /locus_tag="PK063_10915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HMZ97608.1"
                     /translation="MKVIALSDFQQFSQEKMKKNNLFETSRFFCDIYCFEPGQEQKGH
                     IHGEQDKVYIVLEGEGTFQVGTEKRVLKAGQGTMAAAGEEHGVKNHSAERLKVLVFVA
                     PNP"
     gene            complement(14079..15002)
                     /locus_tag="PK063_10920"
     CDS             complement(14079..15002)
                     /locus_tag="PK063_10920"
                     /inference="COORDINATES: protein motif:HMM:NF014774.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoB--CoM heterodisulfide reductase iron-sulfur
                     subunit B family protein"
                     /protein_id="HMZ97609.1"
                     /translation="MPLKFALYPGCAAKGATPELYQSTMAIVGRLGIEVVELAASSCC
                     GAGVIGEADPDLALALNARTFAQAERMGLDVMTICGTCQGVMSAANRRLKSEPATLER
                     VNKILAQDGISYGGGVQVKHLLWIAVRDLGLSRVAGTVRSSFREFRIAPFYGCYMLRP
                     SWELGFDDPENPSSLEKIIRAVGGEPVAYAGRTKCCGFPIILEKEAIAVAMAGTNMKD
                     AKDHGADFMVTPCPLCHMSLDIYQERAGRAVKTELNLPILHLPQLLGLAMGIPAQDLG
                     LSRHLISVDRIVNRLQNPDSTHSSLPAEPRT"
     gene            complement(15127..15573)
                     /locus_tag="PK063_10925"
     CDS             complement(15127..15573)
                     /locus_tag="PK063_10925"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97610.1"
                     /translation="MIAERVLVVLCLTAVGCGLAPLAIAAGDQAPPSTTEKMIRDTKE
                     AVESTKQYTIQQKDSFQKTVQAELAEMQTKITELQKKTSAASVEARKDMQKALQDLER
                     KKDEARKQLDEVSHSTSSAWSTLKDNVNAAVADLKKSYKDTVSKLP"
     gene            15765..16634
                     /locus_tag="PK063_10930"
     CDS             15765..16634
                     /locus_tag="PK063_10930"
                     /inference="COORDINATES: protein motif:HMM:NF020252.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDOD domain-containing protein"
                     /protein_id="HMZ97611.1"
                     /translation="MSAELAPMSDPASTSPLEQLLIERIRKGAIELPLLPQVASRILA
                     MVYDPDAEAAKLAALIHQDQALAAHVIRIANSPAYMTRNPVVSLQHAVSMLGMNLMSE
                     LAFSASIKGSAFKVPGWDGEVKSLWHYSLASGAYAKEIARMRRFNVESAYLCGLLHGI
                     GRPVVLQTLVALAKEQGSPLTKELLHQLLDGYYIQVGLLVADEWGLPPPVVESIGFHA
                     DYHYAKTAKQECMTTCLAGRLAKHFLDPEGFDEATVRDHSVFADLNLYPKDIDALLAH
                     KDKVQAVVEAMPL"
     gene            16634..18052
                     /gene="sthA"
                     /locus_tag="PK063_10935"
     CDS             16634..18052
                     /gene="sthA"
                     /locus_tag="PK063_10935"
                     /EC_number="1.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003957 - NAD(P)+ transhydrogenase
                     (B-specific) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Si-specific NAD(P)(+) transhydrogenase"
                     /protein_id="HMZ97612.1"
                     /translation="MPATAYDIVVVGSGPAGQKAAIQGAKAGKKVVLIEQEPGIGGNC
                     VYRGTIPSKTLRETAVQFERLKRSSEVFEGKMRIDVPMSVLLHRLDEVVKAHECYMAS
                     QLTRNGVTYRHGRARLLSPHEVQLETVDGACQTLTAETIVLATGSRPSSIPEIPVDHE
                     HVLDSDSILSMIYLPRSLTILGGGVIACEYASTFALLGVEVTIIDRAKRPLPFMDHDI
                     VDVFQRSIERQGGRFYSGHTVTEVAWDGVSSVVARLANGMAVKSEKMLVALGRQPNVE
                     ELNLEAAGLSLDEKGHIPVNDHGQTAVPHIFAAGDMLGRPPALASQAMEDGRRAVSHA
                     LGLPVGDSLNQVPIGIYTIPEIASIGLDEEQAAARYRGPIIGRAPFTEIAKGQITGAC
                     DGLLKLVSDPSGERLLGVQIVGENATELIHLGQMALQDGATIDRFIDTIFSFPTFAEA
                     YRVAALDILGQRRKRRDEAQAA"
     gene            18147..19844
                     /locus_tag="PK063_10940"
     CDS             18147..19844
                     /locus_tag="PK063_10940"
                     /inference="COORDINATES: protein motif:HMM:NF024824.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ97613.1"
                     /translation="MNREERRREEKLQGRNAGGPAAALAGLREAQMHHQAGRLDDAER
                     GYQQLLARMPAQPDALHGLGLLLYRRGNLRDALTRLAQARAADARNPVYCFNHGVVLQ
                     RAGLLPDAVDAYNRAIQLNPRYIDPRTNLGNVYKELGRLAEAQATYEQVLALNPDHAE
                     AHNNLGVVLKEQGRLDAAADAYRKAIALKPAHAEAHNNLGLVLLEQGLVDDAIRSFER
                     ALQAHPGYGTALYNLGIAWIWREDIPRALHCFAETAKAKCAHGRPVTDSAVFRSRVKH
                     DAEQIGYLFERGLIGEEWRGYHDALLQLCGRLEPAPGTVSANRVALSPADLQPIAPSF
                     NRLLYIAPCDTIAEGALAPDLDHAAIEARYLATQPEVTYIDGLLSEEALRRLREFCWT
                     STIWKKDYENGYIGAFLGDGFASPLLLQIAEELRRRLPRIFGTHRLTQAWAFKHDSAR
                     RGLNIHADAAAVNVNFWITPDDANLNPESGGLVVWDKEAPREWDFKTYNSDKARGSIY
                     EWLTSQGAKEIKIPYRANRAVVFNSDLFHETDDIAFKEGLTNRRINITLLYGHRHRP"
     gene            complement(19810..21936)
                     /locus_tag="PK063_10945"
     CDS             complement(19810..21936)
                     /locus_tag="PK063_10945"
                     /inference="COORDINATES: protein motif:HMM:NF012772.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HMZ97614.1"
                     /translation="MSQTTPKILIADDDPLARLFVKNALEPAGMIVLEATGGKDALTK
                     FEAIGPDLVILDIMMPDMDGYLTCSRIRSLPRGKRVPILVLTGLDDAQSIGQAYQHGA
                     TDFITKPVNATILCHHVRYMLRTNNVLHALIRSESRLELAQRIARIGNWDWNPKTNRF
                     AMSNELCRLVGVRPQDFAGTFEAFLALVHADDRSIVTGALQKLVAQHTPCDIDHRIVL
                     PNGTDFVIHLQAEGVREEETDEITVIGTAQDITERKQAERAIHQLAYYDSLTGLANRV
                     LFKDRLSNAISYASRHQQHLATLFIDLDRFKIINDTLGHTVGDRLLTHVAERLSESVR
                     QSDSVSRHADQEPMHALARLGGDEFTILLTALPQPEDAGRVARRILESLAHPFSIEGH
                     EIFISASIGISIFPSDGSTVEALLKNADTAMYHAKEQGRNNCQYYSSGLNAAAAERLD
                     LENELRRALEREEFVVFYQPKLNIHSRRILGAEALVRWKHPKRGLVPPGVFLNAAIDT
                     GLIRSMDEWVLREACRQVKAWEKAGLPPITISANVSNSLFHGRTLPTTVADALRDSGL
                     NPAQLELELTESIAMRDVEASVTMLEGLRTMGVRLSIDDFGTGYSSLSYLQRFPLSRL
                     KIDQSFVRDLLTNENNVKITRAIIAMAHSLNLSVLAEGVETEGQLAKLREEGCDEVQG
                     YLFSRPVCAEDFEKLLKGDADARTAA"
     gene            complement(22160..22888)
                     /locus_tag="PK063_10950"
     CDS             complement(22160..22888)
                     /locus_tag="PK063_10950"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97615.1"
                     /translation="MADASASRLPRTWLPALLVSIIISTLCAAALYVLLAQHDRSLVA
                     QRNASAVMAAEYSARATAQTLAWFSESMGGDNFDSIQQTLEQHAQQANLLAAAVIMDN
                     NVVVASSNPAAIGTTLQDAASLAARRTQSGVITSGIEQGRAAFIVMEPFRRDNRVAGW
                     IRLAVATPPEAAAPRSDDDLGRDVALVIAPLLLLTATLLMLTMRGLMSRVRTLLAGIV
                     LEAREQGPHTIPGGLDTTERGEMA"
     gene            complement(22935..23303)
                     /locus_tag="PK063_10955"
     CDS             complement(22935..23303)
                     /locus_tag="PK063_10955"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ97616.1"
                     /translation="MSSFTQRRLTMEQRQHERFPAHFRSAFSSVNRVEGDGTVVDLSL
                     RGCGIVSQTAMHPGTTLTLRIHLPDPETMLTVQQAVVRWCRDGRIGLEFQSLPPDEWA
                     RLQRIVKALTRHPYERTQDA"
     gene            complement(23359..24810)
                     /locus_tag="PK063_10960"
     CDS             complement(23359..24810)
                     /locus_tag="PK063_10960"
                     /EC_number="6.5.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008452 - RNA ligase activity [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RtcB family protein"
                     /protein_id="HMZ97617.1"
                     /translation="MTLNTDMQVNRIDDYLWEIPPSEKVGMLVPARIYASPAILGAMD
                     RGVFDQVTNVACLPGIHRYALCMPDGHWGYGFPIGGVAAFDPEDGIISPGGVGYDINC
                     GMRLIRTDLTRAEVQPKLELLMTELFRRVPAGVGSRGFVNVNRREFREVMRKGAVWCV
                     AKGYGWDEDLERIEERGCLDGADPAHVTDYAIERGINQLGTLGSGNHYLEVQVVSDKN
                     IFDRETAAAMGLTGRDQVVVMVHCGSRGFGHQVASDYLKVFEKAMRRYGISVKDQQLA
                     CAPFRSPEGQEYFGAMNCAANTAFANRQVITHQIREAFAAVFDSTPHALGMHLIYDVA
                     HNIAKVERYGDGEWLVHRKGATRAFGPGSPELPDCYRAIGQPVICGGSMETGSYLLVG
                     TNRAMHDTFGSTMHGSGRTMSRAQAKRSVRGEQLLRDMKQQGILVKAVSMSGLAEEAG
                     LAYKNISDVVNTVDQAGITKKVAELKPIGNIKG"
     gene            complement(24859..25299)
                     /locus_tag="PK063_10965"
     CDS             complement(24859..25299)
                     /locus_tag="PK063_10965"
                     /inference="COORDINATES: protein motif:HMM:NF014058.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="archease"
                     /protein_id="HMZ97618.1"
                     /translation="MPGTFRFLDDIAMADMAFEAEGDSLASLFDAATQALLQSLADPA
                     TVAQTWQQVVDMEEPDIDTLLFEWLNRLVYLKDAQAVVFHHATLTVQAAPGQSAWHLH
                     AELVGAPVDQATQDLRSDIKGVTKHLYAVTQTGNSWKARVVLDV"
     gene            complement(25305..26279)
                     /locus_tag="PK063_10970"
     CDS             complement(25305..26279)
                     /locus_tag="PK063_10970"
                     /inference="COORDINATES: protein motif:HMM:NF004616.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase/fumarate reductase
                     iron-sulfur subunit"
                     /protein_id="HMZ97619.1"
                     /translation="MRLTFTIQRFNPETDQQPHQEEYRLDIGRGMTVLEALIRIKNEL
                     DGRLALRYSCRSAICGSCAMLINGTQKLACRTSIRKELERHGRISIAPLPNLPLIKDL
                     VVDMAPFWEKIRAVTPWLTPITHPTKRYGSSGQLRLLPDSYQFHNVDACIMCAACVAA
                     CTSHEVSRGFLGPAALAKAARFVADPREPADAKQVRLAALQEADGIWDCTRCNMCVQV
                     CPKDVQPMEAIIRLRRSSLRHGLTTAEGARHITGFVDLVRQEGRLNEALMPLKVLGFN
                     LQRVVDVMPLGVRMFFKGKVPLPFGHTIPGIEQVRAIFAAARRRTTRV"
     gene            complement(26324..27481)
                     /locus_tag="PK063_10975"
     CDS             complement(26324..27481)
                     /locus_tag="PK063_10975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro peptidase family protein"
                     /protein_id="HMZ97620.1"
                     /translation="MSHSTDQHTNPVPGATVFIAASETDSNLYYATKFIAPDPFIYLE
                     VKGERLMIMSDLEVDRARHQATVDRVVSYSELERRAKAQGVKDPGNIDVIHLVLQDAG
                     VRDILVPPTFPFLHAQRLQELGYRLRTKRDPFYESRVVKSDEEVRHIEAAQRATEKAV
                     AAAHESLRRAEIRDNVLWLDGQVLTSERVKKLINVALMECDCVAQHTIVAGGEQACDP
                     HDEGSGPLPAHRSVIFDVFPRSADSRYFADMSRTVVRGQPSPELKKLYQTVKDAQEEA
                     ITKIRDGADGAVIHQGICDRFEKSGYKTGVVNGRMQGYFHGTGHGVGLDIHEAPRISR
                     TGSLLQEGHVVTVEPGLYYPGLGAVRIEDMVLVTKDGCRNLTNYPKVFELG"
     gene            complement(27533..30946)
                     /locus_tag="PK063_10980"
     CDS             complement(27533..30946)
                     /locus_tag="PK063_10980"
                     /inference="COORDINATES: protein motif:HMM:NF024893.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA-like C-terminal domain-containing protein"
                     /protein_id="HMZ97621.1"
                     /translation="MRVRPRTVVLSLLGLVVAGILLLFYSRELFGVDILKNFFLQQLE
                     TSLRRKIEVDRIKLVVLPSIRLELTNVGIYGHDDPTHVVFSAKEIDIVLRLLPLLKKQ
                     VVAKRIFLNEPTVTLVRNRSGHWNVLAGMPSAAKDESAYQMFSRLLQIREATIQKGHI
                     TVTDEARPDGVRTTTLETVEMALKVYPGKAEGDLHISAALPANGAPSSFSLTGTIGLS
                     ESSSTLAAEEPYSVRPAFQFEGEIDTTNLRLREAADFFGPRPVPPQLQGGASLQSRIR
                     VAPGVAGYDVVLSEIAANVDELAVTGKANLAGLLTSQPTFSITFAAPSIDLRSLFTRI
                     PAQWIHAQLPAIIEQRQLGGTVEILSATLTGATAPSPQLSLTGDFRIDKGMALIGNDR
                     VPTQNLAATVSVEPGRIRVGKVTGAYGSLQITDGKALVSFLDDGPWMELDVSGDMSAA
                     DLVKFLTKTIRADKLTSLLAQSRDIEGQTHPTFRLVGPLDKPEGITFAGGEVLAEQVS
                     LMNPSLPQRLTAMRGRIVFSQTGGAQFDQVTANVGEAQLQFNGMISGGTPSVFQDFVI
                     RAKGSASQLRQMVSAGTFPDDLLYGMVNARVQLSGPSGAPHLRGEIGLNEAKLVLPTL
                     GEKPLGSPASLELDADVSKGIGLVISRLELVVPPLRLPLKGRITLGDQFSIDASLATG
                     TVSVSSLPDWVYRSGFEAGNLEVSMDVKGSDAEWKNWRAGGWLALTNGLMTLKGVDGA
                     VEDIYLRLKFSKNIADIKQLSFRIKDSDVSLSGALKNWTTKPVIAVKIESAQMDLDLL
                     IPKGHRSPIREFLETLASTSQVSATATIEKGLYKHLRFGGLSGRLTIQDGMLDLDRVV
                     AQSGTGHAAGRMVVRLPKGEPAETESSVRMTGIPAEAVLQLLGAHDQPVTGDMKLTGA
                     LRGHGRNPHGVLPTLNGKVELVLQDGRILKTEKRAIWKILSILNLPAVLQGKVDLEKE
                     GLQYNRASATLTVQNGLVKTQNIILDSAVLKISAVGTYDMPTDQLDMIWAVSPFGSYS
                     QFLKSIPLFGRLVAGDRKGLATALFQVKGSIDDPQVTYMPMKSFTTGLTGVAQLAFDL
                     LKNTVMLPIDILAPQEEKEPLFDPSLEIQTPPSAPPPVDVPAATAPAAP"
     gene            31105..32391
                     /locus_tag="PK063_10985"
     CDS             31105..32391
                     /locus_tag="PK063_10985"
                     /inference="COORDINATES: protein motif:HMM:NF019310.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HMZ97622.1"
                     /translation="MRRPLNGGTLGESRVGLDTSAVRPRWGILALLFAISAVTYMDRV
                     NISVTARQMMPAYGLTDQDMGYVFSAFVFGYALCQIPGGRLGDRWGARVVLACALLWW
                     SLCTVLTAVVATLPVAGLVGTVGALVIVRFLLGVGESVALPNFNRAVADWMPPGQRGL
                     GIGIAIGGIGIGAAITPPLASWVMVNYHWQSVFYLSALIGLMVALLWVLFSRDGRSDA
                     TAKADTIPTPVPWGTIFRSRPLWWLVASYTCLGYVAYIYMSWFYLYLVNVRGIDLLRG
                     GWLAAGPFLAILLFCPLGGWVTDKLVPTIGLRRARLSIGMLGMALAGGLIAVGAWVES
                     QTLAIVCLSLGAGWLYFTVGAYWSVTTDLSKTHAGTLSGVMNTGANVGGVISPSLTPW
                     LADHWGWTASLLVAAGIALCGGLMWMKVNPEDGLRE"
     gene            complement(32423..>32905)
                     /locus_tag="PK063_10990"
     CDS             complement(32423..>32905)
                     /locus_tag="PK063_10990"
                     /inference="COORDINATES: protein motif:HMM:NF012927.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HMZ97623.1"
                     /translation="LEVFDAVRAAFRSDRPVTVRVSGTDWVEGGWDIEQTIVFAKALE
                     ARGCAGIHLSSGGLDPRQQIPVGPGYQVPLARAVKQAVSMPVIAVGLITDYDQAEEIL
                     SRGDADMIALARAILYDPRWPWHAAAHLGGQVKAPKQYWRSQPSRYRDLFLKEHGEAR
                     "
BASE COUNT         6306 a         9785 c        10041 g         6773 t
ORIGIN      
        1 cctcgggcat gggccccacc ggaggccggt agggttggat cggaccggac gggattgccg
       61 gggcctttcc tgcgggatga tagtgtttca tggcgtccgg gatccaggcc tcgatctgat
      121 tgatgcgggt gacgtcggac ggatgtgtcg aaaggaactc cgggatcgcc tgctgcgaac
      181 ggaagcacag cttgttgatc atggcgcggg gacagccgct catccgttcc cagaacgaca
      241 ccgcttcgcg cgggtcgtat cccgcctcgg ccatcaggcg cagaccgata aaatccgcct
      301 ccgattcctg gcggcggtcg aagggcaagg aaacgccgac gccatagacc gtcatcgcag
      361 ccatggctgc atccggccgt cccacggcgg caccggcccc taaggcggcc agttgtccga
      421 tctgttcgag aatgccgcga ctcatccgtt ccgctccgtg gcgctgcagc gcatgcgcca
      481 cctcatgacc catgacggtc gccaacccgt cttcggtctt ggtcactttc aaaattccgg
      541 tgaagactgc aaccttgccc ccggggagcg cgaaggcgtt gatcgtccgg tcgtcctgaa
      601 tgacggcgaa ttcccattgg tattccggtt tgttcgccgc cttggcgatg cggttcccca
      661 cccggtgcac catctcgttg agctcggggt tgtcgctcaa gggcgcttgc cggagcactt
      721 cccggaaggc cgagagaccc atcgccattt ctttttcttc cgacagataa atgaactggt
      781 cgcgcgccgt ccccggtgcc cgttgacacc ctccgagcga ttgcagcagt cccgtcgcgg
      841 ctccaagccc catggtcgtg gccaacagcg aagcggcgcg cgcacccagt gcgagggcgg
      901 tacgtcgccc gatcggcgtc ttcagcagcg tttcgattga atgtcggttt gacggataca
      961 tcacgtctgc tccattcaat cagccccgcg cggcggaagc aactcaccgg cttacggcat
     1021 ccacagatac atgaattgcg gtgacccgcc tcgcacgacc gacagcagat cgacgttcgc
     1081 cagactggcc aggctgggcg ccggcgcgac gagccgcgaa tagacattgt tctggtattc
     1141 gccgggccgt cgataggtca cgaccttcgc gtccgtcaag ccggcttttt tcttggccag
     1201 ttcaatcgcg tcgtcgaggt agccgatatc atcgaccaat cccgcagcct tggcctgttc
     1261 gccggaatag atccggccgt cggcgagctt cttaatggtc tccccgttca tgcccgggcg
     1321 gccttcctgg accacctgca gaaaccgctg ataaaagccg tcgatcacgc cttggaaaat
     1381 cgcccgttct tccggcagca tcgcgcgaaa cggcgagccc atgtccttgc ggggaccgga
     1441 ggtgacggca ttcgtttcga cgccgacttt ttcgagcagg cctctggcat tgacggtcag
     1501 catgatcacg ccgatactgc cggtgaccga tgagggatgc gccagcaccg tatcggctgc
     1561 ggcggcgatg tagtatccgc ctgacgcgcc cacgtccatg atggaggcca caataggaat
     1621 tttgcggctg gtcttaaagt ttctgagttc gtgataaatg atgtcggacg cggtgacagt
     1681 ccctcccggg ctgttgatgc gcagcacgat cgctttgacc cgttcgtctt tggcggcccg
     1741 ctccagctct tccttcaccg tggccagcat gccaggcgaa gaataaaagc cgtccttgtt
     1801 ttcggagctg atcacgcccg acacatccat gagcaggacc ttgtctttgc cggtcccgct
     1861 gaccttgtgt tcttcgagcg cgccggggcc cggcggcagg ttgatcgtga cgcaggccgc
     1921 ctgcatcagg gccagggcca acacaagcag accggtcgag agctgccata cgtcgggagc
     1981 ctgaccgacg ttgcgcttca tagcgaggcg aaggagctgc ggccagatgc gaggccggag
     2041 gcctgaaaaa accggaagtg tattcgcaga attacattga ggatttttga gggccgagaa
     2101 cgacgcagat ggccgcaggt cattcgccgc agcagagcgg tcaatatcgg acaggctcct
     2161 aggcatggtg tgtctccatc aatgcgacaa attgttcaaa cagataggcg gaatcatgag
     2221 gaccgggaga cgcctcggga tggtattgca ccgaaaacac cgggcgatcc agacaccgca
     2281 tgccttccac ggatgcgtca ttcaagctgg tgtgggtcaa ttgcacccga ccgaacggcg
     2341 tatccacgat cggcagttcc tgacccacaa ccggagtttc gccggggaac cgcacggcaa
     2401 agttgtgatt ctgagaggtg atttcgacct ttctggtgcg caggtcgatg accggatgat
     2461 tggcgccatg gtggccgaac ttcagtttgt acgtggagaa tcccaacgcg agccccagca
     2521 attgatgccc caggcagatg ccgaaaatcg gcacgcggcc gatgagctca cggagtgcgg
     2581 tcatggcgta gggcacacct tccgggtcac cgggaccatt cgagaggaac aatccttgcg
     2641 gattcagggc caacacatcc tttgccggag tcgaggccgg caccacggtg acctcgcacc
     2701 ccacatccac cagccgccgc agaatgttct gtttcacacc gaaatcatag gcaacgacgc
     2761 gccaggtttt gcgcggtgcc ttcgcggccc cctgttccgg catcgtgatc ttcggcgccc
     2821 aatcacccgt gccttccgtc caggggtaac gatgttcgca ggtgacggtg gctgccagat
     2881 cacgcccgat gatgctcggc gcctgccggg ccttctcggc cacgcggcgg gggtcgagat
     2941 cgatgtggga aatgacgccc ggttgggcgc cccgctcccg caaatgcctg gtgagcgctc
     3001 tggtatcgat gccctcgatc gccacgatat gagcggcctg cagatactct tgcagcgtcg
     3061 acttgcctcg ccagttactc gccagccggc tggattcctt cacgatgaac ccttcggccc
     3121 agattttcgt cgactcgacg tcctccggcg tgacgccgta gttgccgatc tgtggagacg
     3181 tcatggtgac gatctgcccg cgatacgaag gatcggtcag aacttcctga tagccggtca
     3241 tagccgtgtt gaagacgact tcgccgccgg tctccccttc cgcgcctaaa gctcgccctt
     3301 cgaaccaggt tccatcggca agcgcaagaa tcgctttctt cactctcact ccttcactcg
     3361 gatccaggac cgcacgcgca gggtcaacag cgcgataccg agtcccacat tcaggatata
     3421 cagcacccgt accggtttat gtagctgaaa gaacgcctca aaggctgcct tcctcgcgtc
     3481 ctcccctttg gaggcaaagg cctgcgcctg caaggcggcc gcctgaggat gcagcacaaa
     3541 cgtgatcaca ccggcaatga gcagcattgc gcccagcaac aaccactcgg ctctggtgat
     3601 ggcttcgtcc gtcattccct gttgatacaa ccaggctcgc cagagaatgc ctgcgatcag
     3661 aatggccgcg gcgccaagca ccagccgatt atacccgtcg aacgcgcgcg tcaggaaaaa
     3721 tcccccggtg tcctgtccgc cgaacgtatt gaacacggcg gggatgacag ctgccacgag
     3781 gacgagaagt ccgccgatcc agacggctaa tgccagcatc tcgaaggtca cacaggcgat
     3841 caatccttga cgcacgatcg tctcgtccta cgcctgccgt cctgggcgat cgagttcgta
     3901 gacgacccgc ccggagacga gtgtcgtggt gacacgccct ttgactttcc atccggcgaa
     3961 cggcgtgttc cggctcttgg aacgaaatcg cgagggatcg acttcccatt ccagattggg
     4021 atcgacgatg gccacatccg ccggcgcgcc gaccgccagg gtgccggcat tgagactgaa
     4081 cgccttcgcc ggagccgtgg ccagcttatc gacggccgat tcgagcgtga gcaccccttc
     4141 ttcgaccagg gtcagcgtca gcggcaacgc ggtttccagt cctacgatgc cgaacggcgc
     4201 ctcggtgaac tcctgttgtt tctcctggct ggcgtgcggc gcatggtcgg tcgcaatgac
     4261 gtcgatggtg ccatcacgta atccgtcctt gatcgcctgc acatcctgac tggtcctcag
     4321 tggcggattc attttcgcat gggtgttgta gccgcgggtc gtttcctccg tgagggtaaa
     4381 gtgatggggg caggcttctg ccgtcacttt gagcccccgc gccttggctt cgcgcaccat
     4441 ccggaccgaa ccggccgtgc tgatgtgcgc cagatggaga cgcgctccgg tcagttcggc
     4501 gagcgagaca ttgcgcgcca ccatcacatc ttccgcggcc gacggaatgc ccgggagtcc
     4561 cagttcggtc gagatcagcc cttcattcat gcagccgcct tcggagagat gcaaatcctc
     4621 gcagtggtcg acgaccggta cgtcgaaggc gcgcgcatat tccatcgcgc ggcgcatgac
     4681 gaggctgttc atcaccggct ttccgtcgtc ggaaatcgcg acacatccgg cgcgacgcag
     4741 gtcgccgatc tccgccaatt ccttgccttc ggagcgtttg gtaatggcgc cgatgggata
     4801 gaggttggcg gtgcctgccg ctttcgcccg ctccagcatg aattcggtga ccgcttggtt
     4861 gtcgttcacg ggattggtgt tgggcattgc gcagactgtg gtgaaacctc ccgcaacggc
     4921 cgcgtccgtt cctgactgaa tcgtttcctt gtattcaaag cccggttcgc gaaagtgcac
     4981 gtggagatcc acgaagcccg ggagcaccaa ctgcccccca gcctgaatca ccgtcgcgcc
     5041 ggccggtgcg gcgagctttt gcccaaccgc tgcaattttc ccgttttcaa tgaggacatc
     5101 cgcgatgccg ttgacgcgtc cgggatcgat aacgtgaccg cccttgatca gaatcatagt
     5161 gcgctgttca actcccccta ttaaacaatg taaaccatgg tttcatgtgc cggcgatctc
     5221 ctgtgaggag atcgtctcat cacgtcttac gcattggctc ccgacatgag atacaaaatg
     5281 cccatacgca ccgccacgcc gttggccact tgatcgagga tcacggacga caggctgtct
     5341 gctacgtccg gtgcgatttc gacgccccga ttgatggggc ccggatgcat gacgatcgcg
     5401 cccggctcag ccagtttgac ccgctcgttg gttaagccgt actgccgggc atattcgcga
     5461 atggtcggga acaaggcgcg cccctggcgt tcgagttgaa gccgcagcat catgatcaca
     5521 tgcacgcccc gcaacccttc atccaggttg taatacacct gggcgccgag ctggttgatg
     5581 tgtagcggaa tcatcgtcgg tggtccgacg acccgcactt cggctccgag tttcgtgagg
     5641 gcgaaaatat tggaacgggc cacgcggctg tgtgcgacgt cgccgacaat cgccaccttg
     5701 agcccagaga accccatgcc gcggctgcgg atggtgtaga gatcgagcag cgcctgagtc
     5761 ggatgttcgt gccacccgtc gccggcattg atgacggaag acttgacgcc tcgcgccagt
     5821 gtttccgccg cgcctgccga tgaatgccgc aacacgatga tatccgcctg catggcttcg
     5881 atattgcgcg cggtatccag cagcgtttcg cccttcacca cactgctgga cgaaggggaa
     5941 aaattgatga catcggcgct gagccgcttg gcggccaatt caaacgaggt tctggttctc
     6001 gtgctcggct cgaaaaagag gttcacgacc gtcttgcccc gcaaggccgg caccttcttg
     6061 atctcccgcc cggagacttc tttgaacgaa tctgccgtgt ccaggatcag ggcaatgtcg
     6121 gcagctgaca aattggtcag gctgagaagg tctttgcgtt tgagccccac gtcactgtct
     6181 ccggttacgt cctgaggatg accacgcggt cctcttcccc gttttcttcg agatggacct
     6241 caatggcctc gtcgcgcgag gtgggaatgt ttttcccgat atagttggct ttgatcggga
     6301 gttgccggtg accgcgatcg accagcaccg ccagctggat ttccgccggc cgtcccagat
     6361 ccatcagtcc gtccatggcg gcacggatgg tccggcctgt gaagagcaca tcgtcgacga
     6421 gcacgacctt caggtcagat attttgaacg gcaccgaggt ggtgcggagg atcggttgat
     6481 ccttccgcaa cgagaggtcg tcccggtaca gcgtgatatc cagttcgccg atcgggatct
     6541 gggtgccttc aatgtcatgg atgcgccgca cgagtcgatg cgccaggtgg acgccgcccg
     6601 ttctgatgcc gacgagggcg agatcttgaa tgcctttatt ccgttccagg atttcgtggg
     6661 caatgcgggt cacggcgcgg gcaatatcgc ccgcgtccat cacgacgcgc tcctgccggt
     6721 tgccggttgt agattccgtg gtcatgagtg gccgatcagc tggaggcata aaaaaacctt
     6781 ctcctccggt gtggacgaga aggtgcgggt tgtcggacgg cttgagccgt gcatcatgat
     6841 catgagctcc ttacccacct cacaggatga gcgttaaagg cgagccgatc ttaacgagtt
     6901 gatccaaccg tgtcaagaat tcactgcagg cgatgggctg atgagaggga catgccttca
     6961 ttgactccat gcatgccatt tgttagcttc gtcccaccga aagcggactc tcgctctcga
     7021 tctctttgtc aatcaggtca tccagaatca tcagctccca tcgtgaaagg atcgcgcatg
     7081 acttcccctt ctggttccac cacaactcct gatctgttga ccgccctcgc caatacagcg
     7141 accaacctcc gcatcgacag cgtcaaagca acgagcgaag cagggagcgg acatccgtcc
     7201 agctgttgct cggccgcgga cattcttgcg gtgttgttct tctcggtcat gcggtacgac
     7261 cccaagaatc cgaagttgcc gaatagcgac cggtttgtcc tctccaaggg gcacgccgct
     7321 cctctgctct atgcggcctg ggcggaagcc ggattatttc ccaagtcgga gctgttgaaa
     7381 ttgcgcacgc tcggctccga tcttgaaggc catccgacgc cgcgactctc gttcgtcgac
     7441 atggcgaccg gttcattggg ccaggggctg ccggcgggtg tcggtctcgc gttcaatgcg
     7501 aagtccatcg acaagaccga ctaccgcacc tatgtcctga tgggcgacgg cgaatctgtc
     7561 gaggggtctg tgtgggaagc cgcggaagtg gctcgccaag cgaagctgga taatctgtgc
     7621 gccatcgtgg acgtgaatcg gttgggacaa agcgatccga cgatgctgca gcatgatatg
     7681 gacgcctacc gcgcccggtg gagcgggttc gggtggcatg cgatcgtggt ggacggtcac
     7741 gatatcagcg ccctggtcgc ggcattcgcc gaggcggcga agacgaaggg gcagccgacg
     7801 gtcttgctgg caaagacctt caaggggcgc ggcatttcct ttatggaaaa tcatccggac
     7861 tggcacggga agccgctgaa gaagggcgaa gaaacccaaa aggcgttgga cgaattgacg
     7921 ggccaattga aaccgagctc gacccgcctt cagatctcgt tgccgactgc agccaagacg
     7981 gctccgtcca cgaagggcac gctggctccg gcaccgtaca aggtgggcga ttcggtggcg
     8041 acgcgggaag ccttcggggc cgccctcctg gcgcttggcg aggcgaactc tcaggtggtc
     8101 gcgctcgatg cagacgtgaa gaactctacg tacagtgata agttcggtaa acggtttcca
     8161 gaccggttcc tcgaaaactt tatcgccgag cagaatatgc ttggcgctgc ggccggcatt
     8221 gcggcctgcg gcaagattcc gttcgtggcg accttcgcgg cgtttttcac gcgcgcctat
     8281 gattttattc gcatggcggc gatcagccag tcgaacatta aactggtggg gactcacgtc
     8341 ggtgtcagca tcggtgagga cggcccgtcg cagatgggac ttgaagatct cgccatgatg
     8401 tcgacccagc ccggcgtgac cgtgctctac ccgtccgatg gcctgtcgat gtacaaattg
     8461 atggaatcgg cgaccgccca caaggggatg gtgtatctac gggccggtcg tcccaagacc
     8521 cccgtgatct atagtgcgga cgagacgttc aagatcggcg gttcaaagat tctgcgacag
     8581 agtgccgccg accagctcac gatcgtcgcc gccggtgtca cgctgttcga agccctcaag
     8641 gcccacgacc agctgaaggc agccggcatc gccacccgcg tggtagattt atacagcatc
     8701 gtgcccgttg accaggccac cttgatcgac tgtgcgcgag cgacgggtgg acggtttctg
     8761 acggtcgaag atcattatgc gcacggcggg atcggcgacg ctgtgttgag cgccctggca
     8821 tcagaaggcg tacgggtgcg caagttggcc gtccgggaca ttccacgtag cggaaaaccg
     8881 gacgagctcg tggatcattt tggaattgga gtgcgctcga ttgtcgaagc agccaaagag
     8941 atcgccacag cagcccgccg ctgaacggcc cagccccggt gctcctgccg ggttgaatca
     9001 gattcccctg ctccagatcc tcagcgccca ggatcgccaa aaggtcctgg gcgaaatgac
     9061 tgaaacccgc tacgggaagg gcgactacat tttccgcgaa ggcgatccga ccgaatactt
     9121 ccacatcgtc aaggaagggt cggtcaaatg cgtcaagtcg tcgctcgacg ggaaggaatg
     9181 cacgctcaaa gtcttgatgc cgggtgattt gttttgttgc gatgcctcgg ccttcgacgg
     9241 tgcgtcccac cctggcacgg cccagcccat gggcgatgtc agtgtgcttc gcatgaaaaa
     9301 ggaagcctac ttcaagatgc tccgggcgaa tccggatgcc gcgatggaag tcatccggta
     9361 tttgggaaac cggctcaatg aagcccagga aaaagccaaa gtgcttgccc tcgatcgagc
     9421 cgatcaacga ttggcttctt tgctcgtgag tctggcagaa cgcagcggga tcaaggaccc
     9481 caacgggatt cgggtcaccg ttcgtctgac gcgccaggac atggccaaca tggtgggcgt
     9541 cacgacggaa accgccatcc ggatcatggc gcgcttcaaa aaggatcgat tggtgaccgg
     9601 caccgccgcg cggctcgtca ttcgtgatct ccccaagctc aaactcctcg cttccacgta
     9661 atttctttcg ccacagaccg ggtattttta aaaacatgac aatagtcatg ttttgttgat
     9721 gccgccatct cgtatggtgc aaccagaggc gcagcattcg atcgcgacga atgttgatcc
     9781 gggagcattg cgcttccggt cgccgggttc aacacaggaa tggcggaggc aacatgtaca
     9841 cacatacaga ccatcgaggg gggagaaccg gcaaaacgat catgttcatc ggggtcatgc
     9901 tgagtatgct ggcaggcatg gcgctgtcgg cccaggccaa aacgcatgac attaagatga
     9961 ccgcggtgga gacggacatt gtgatcgacg gcggcggtga aaaatatgcc gcctggacgt
    10021 tcaacgggca gtttccgggg ccggtcgtgc gggtgacgga aggtgacacg atcaatttca
    10081 ccctgacgaa tcctgcgacg aacaagaatc cgcatgcgat ggacttccac gcggctgaaa
    10141 tcgatttcct gaaaaattat cgggccgtca ataccggcga aagcatcagc ttcacctttg
    10201 tggcgaaaaa gccgggactg tttttctacc attgcggagc gccgcctatg attcaacatg
    10261 tcgcgcgcgg catgttcggc gcgatcatcg tcgatcccaa gaatgctaaa gtctggccga
    10321 aagcggatcg ggaatatgtg ctggtgcagt cggagtatta taagaacccg aacgatgtcc
    10381 aggccatgtt cgatcgaaag tacgacggca tgatgttcaa cggcggcatc ttcaagtatc
    10441 accccttcgt gaccggcggg ggaaaactcg atgccaaacc gggagagcgc gtccgcatct
    10501 atttcgtcaa cgcggggccg aacgagttct cctcgttcca cccgatcggt gagatctggg
    10561 acaacgtgta cgagagtggc aatcctgcca acaatctgaa gggcgtgcag acgtacgtcg
    10621 tagggcccgg cagtgccgcc acgtttgatg tcgtggtgga atctgccgga gcctatccgc
    10681 tcgtcacgca ttccttaacc ggggcattgc gtggggcgat tgcggtgttg ctggcgggac
    10741 cggatgcgaa accggcgccg ttgatgccga tggtcccgtg ggagatccca gcgaagtaga
    10801 ccgtttcgtg atcgaatctt cggccggccc ctaaggggtc ggccggacaa cgcgagagat
    10861 caacaatgac gacaccgttt atgcatggat cgtggtttct tggagatgcc gatgcgatgt
    10921 cctgggatga cgctgagttg cttactcctg ttcgccgggt gcctcgtgag tccagccagt
    10981 gccgacacct cgcgcgagcg agtggcgctc ttcttatccg gccaagattg tccctcttcc
    11041 cgccggaata tcgctgcgga actggcgcaa gtagcaggcg tcatccgcgt ggacatggag
    11101 agcgttcctg accatgcgct ggtcgatgtc gtgatcggtg cggtgagtcc ggacgatctt
    11161 ctggtggcgg tgcaccgctc cgccctcaag ggcgtggatt gtcgggcgga ggtcatgaag
    11221 tcatgcattt ccgccggtcg ctctgcagct gatcggtgac cagcacgtgc cacgactggt
    11281 tgatcgaggc gaccgggcca cgctcacgcg aaggtctgcc atgcggacaa cggtcttaaa
    11341 ggggcaacga gggatcgcct ggcccttttg gctggctgtg atggccacag tctggctgtt
    11401 gcctgtggcg ccggtggtcg ctcaggaagc ggtccttgaa tttcccattc ggccttttaa
    11461 tgtcgatgtg atgctccgcc agcagacgtt tgcgccagac gatcgtgaga tcggcgtgca
    11521 gctcggcatt acggcggtac gctacggcaa tgtcgaggtt cggaccatct atcaattctt
    11581 cagcatccat acgcaggact tcagcaccga ccagcattcg ctgttcgtga atcctcgctg
    11641 gaataacttc atcgacatcc tggattttcc caagcacaaa ccgatcagcc gcatcatccg
    11701 ccatgtgctg tttggaccgt tggaggatcg ggccgttccc tatgtgggag tattggccgg
    11761 aggtgtcttg cccggccctg gtaaccgtgc tccaggccat ttgatcggcg gccaggtggg
    11821 agtgcggttc ccggtcgcac agagcctctc agtggatatc agcgtgcaat acagtcaata
    11881 cggggtggat tttcgcggag acgcgggaca ggcgcagcaa tgggtattcc tgacagggat
    11941 acggttttaa tcaaggcaac ctggtgcggc cgaatctggg cagcactatg ctgtctgctg
    12001 ttgtccggct gcggcttgct catcgatgcg gttgaacagg tctggccggt cgccggcagt
    12061 aaagtcgata tcatctgcga acgcgggcgt gttcaggtcg gcctggcgat ggagccgttc
    12121 cgtcccttcg tgtttccgac gatctggacg gacgaagggg ctcgtgtcac ggggctcgat
    12181 gtcgaactca cccgggccat gacggacgaa ctgtcccgac ggtgcggaca tccggtgact
    12241 cccgtcctgc atctcgtgcg cttcagggat ctgttccggc tcctgaatga aggacacttg
    12301 gattggttcg tgtcggctgt cgcgacaaac acgcctgccc cgtcccgcgc cggagtcgcc
    12361 tattccctgc cctattttta cgggggaggt atcagcggga tcacaacgag cacgagcgtc
    12421 ctggagcggg tgcgggagaa tcttcagcaa caggcgacgc atcctgcagc cgatcggctc
    12481 gcggccacga gtcatgcgct ggatggcctc accatcgcgg tgcaggatga aaccagcgcg
    12541 tactactatg ccgaagccaa ctggggcgcc aaccggctga tcgtgtgcga ttcgttaccg
    12601 gcagccttcg aatatgccga cgccaagacc gagccgcgtg tcgatattat tctgggcgca
    12661 caaccggtgt tggaatatat ggtcaagcgg gttcgcaagg actggtcact cttgacccgt
    12721 gagaacggcc gccccctgtt cctgaccaag gccgactacg gagtggttgt ggctgaggag
    12781 agttaccgcc tccgctggct ggtgaacgat ctactgttga aactggacga atccggtcgc
    12841 ctgggtgaga tgcggacacg ttggctcgac gacgagtatg cgtttccccg gagagcctcg
    12901 ttggaaggat tacccttcga tgtggagaag atggcgtccc actacatcca gggcacctgc
    12961 cgcatcaggc ccggatcatg accgcctgga gaggagcaca atcatgagac gtcgtgcatg
    13021 gatcgccctg gctgcagtga tgctgctgat gtgcctgcat ccttcgatga gcgtagcggt
    13081 ggagcgagcc gaggcggagg aaaccgcgcg cctgctggcc aaactgttgg aatcagggcg
    13141 ggccgtcatc gaacgcaacc agtcgttgat cgacgatcct cacaagggcg aaaagggatt
    13201 cacaccggag ttattcgagc agcaattgat ccgggagttt cacgccaaga ccgggattga
    13261 cctgaacgcg ctgccggccg cgccggtgtc tctacgcatt ccaccgctgg cgaaggagct
    13321 gctgccagcc ttggtccagg ccagccgcga ggtcgtccgt gatgcccagg tcgtcatcaa
    13381 tcagcgcggc atcggctaca agaactttat tccggccaca tacggcagtc aggcctctgc
    13441 gcggttctcc aaggccgcgc atgtgcggct gaagcagacc actatccaac cgcggaatcc
    13501 gaaaaacgag cccgacgagt acgaagcgtc ggtgttgaaa tggctctccg ccaggcccag
    13561 ggccgaggcc tatgtgagcg aattgaccga cggagggcgt accctacggg tagtcatgcc
    13621 gatttattac gccaaggatt gtctggcctg ccatggagaa ccgaaaggtg atctcgacat
    13681 ttccgggtat cccaaagaag ggcatcagga gggagatctt gccggagcga ttacagtcac
    13741 cgccccgctg gggaatcgat aacctcaggg atttggcgcg acaaacacga gcaccttcaa
    13801 acgctccgcg ctgtgattct tgacgccgtg ctcctcaccc gcagcggcca tcgtcccctg
    13861 tccggctttc aggacacgtt tttccgtgcc cacctgaaag gtgccctcgc cttccaacac
    13921 gatgtacacc ttgtcctgtt cgccgtgaat atgccccttc tgttcctgtc ccggttcgaa
    13981 gcaatagatg tcgcaaaaaa accgcgacgt ttcgaacagg ttattcttct tcattttctc
    14041 ttggctgaac tgctgaaaat ccgaaagggc gatgaccttc atgtcctggg ctccgcgggt
    14101 aaagatgaat gggtactgtc cggattctgt aaacgattga cgatacgatc gactgaaatc
    14161 agatggcgcg acaggcccag gtcttgcgcg ggaataccca tggccagacc gagcagttgc
    14221 gggagatgca gaatcgggag gttcagttcg gtcttcaccg cccgccctgc gcgctcctga
    14281 tagatatcca ggctcatgtg acagagcgga cagggcgtca ccatgaaatc cgcgccgtga
    14341 tccttcgcat ctttcatatt cgtgccggcc atggccaccg cgatggcctc cttctccagg
    14401 ataatcggga agccgcagca tttggtccgg cctgcgtagg cgaccggctc tccaccgacg
    14461 gcgcgaatga ttttttccag cgaactggga ttttcgggat catcgaatcc cagttcccag
    14521 gaggggcgaa gcatgtagca gccgtaaaac ggagcgatgc gaaactcgcg aaatgatgag
    14581 cggacagttc cggccacgcg actgagcccg agatcgcgta ccgcgatcca gagaagatgt
    14641 ttcacctgca cgccgccgcc gtaggagatg ccatcctgtg cgaggatctt gttcacccgt
    14701 tcaagcgtgg ccggttcgct tttcagccgc cgattggctg cgctcatcac gccctggcag
    14761 gtcccgcaaa tggtcatcac gtccagcccc atccgctcgg cctgcgcgaa ggtgcgggcg
    14821 ttcaaggcga gcgcgaggtc cgggtctgct tccccgatca cccctgctcc gcaacaggac
    14881 gacgccgcga gttcgacaac ctcgatgccg aggcggccga caatggccat ggtggattgg
    14941 tagagttcag gcgtcgcgcc tttcgcggcg caaccgggat agagggcaaa tttaagcggc
    15001 atgggcctcg tcgagtagtt gtcctgcttg tccttgcacc ttaccgtatt ttccccctcg
    15061 atgaacagct cgggcggtga ttcattgacg gggaaccccg cgtgttgaga aagtcggctg
    15121 tccaggtcag ggcagtttgg acaccgtgtc cttataactt tttttgagat cggccacggc
    15181 cgcgttgacg ttgtctttca gcgtgctcca cgcagaactg gtcgagtgac tgacctcgtc
    15241 cagctgcttg cgggcctcgt ccttcttgcg ctccaggtcc tgcagggctt tctgcatgtc
    15301 cttcctggct tccacggagg cggcgctggt tttcttctgg agttcagtga tcttcgtctg
    15361 catctccgcc agttcggctt gaaccgtctt ttgaaagctg tccttttgct ggatcgtata
    15421 ctgcttcgtg gactcgacgg cctccttcgt gtcccggatc attttttcgg tggtcgacgg
    15481 cggggcctgg tctccggcag cgatggccaa gggggcgaga ccacacccga cagccgtgag
    15541 acagaggacc acgagcactc tttctgcaat catggctggg actccttcat gaatggaaac
    15601 agcctgtaag acaaggggtg aagccgatgc ggaatacctc aaattatctg gcatgttctg
    15661 tgcccggagc cttctccgcg ggaggttaag gttttcggcg aaatgagccg aaaaggatct
    15721 acaacgaaga caatcccgca accttgacct gtggtgtgag ccctatgagt gctgaacttg
    15781 ccccaatgtc agatccggcc tcaaccagcc cgttagaaca gctcttgatc gaacggatcc
    15841 gcaaaggagc catcgaactc ccgctgttgc cgcaggttgc ctcccgcatt ctggccatgg
    15901 tgtacgatcc cgatgccgag gcggcaaaac tggccgcgct cattcaccaa gaccaggcgc
    15961 tggccgccca tgtcatccgg attgccaatt ccccggcgta tatgacccgt aatccggtgg
    16021 tttccctcca gcatgccgtg tccatgctgg gcatgaacct gatgtccgaa ttggccttct
    16081 ctgcctccat caagggcagc gcattcaaag tgccgggatg ggatggtgaa gtcaagagtc
    16141 tctggcatta ttccctcgcc agcggagcct atgccaaaga aattgcccgc atgcgccgat
    16201 tcaatgtcga aagtgcctat ctctgcggtc ttttgcatgg catcggccgg cccgtcgtgt
    16261 tgcagacgct ggtcgccctg gcgaaggagc aaggcagtcc attgaccaag gagttgctcc
    16321 atcagctgct cgacggatat tacatccaag tgggcctgct ggttgcggac gaatggggcc
    16381 ttccgccgcc cgtggtggaa tcaatcgggt tccacgccga ttatcattac gccaaaacgg
    16441 cgaagcagga atgtatgacg acctgcctgg ccggtcgctt ggcgaaacat tttctggatc
    16501 ctgagggctt cgatgaagcc accgtacgag accattcggt ctttgccgac ctgaacctgt
    16561 accccaaaga tatcgatgcg ctcctggccc ataaggacaa ggtccaagcc gtcgtggagg
    16621 cgatgccact gtgatgccgg cgaccgccta tgacatcgtt gtcgttggca gcggaccagc
    16681 gggccagaag gccgcgatcc agggtgccaa ggcaggcaaa aaggtcgtgc tgatcgagca
    16741 ggagccgggc atcggcggaa attgcgtgta tcgggggacg atcccgagca agaccctgcg
    16801 cgagacggcg gtgcagttcg agcgcctgaa acgatcgagt gaagtcttcg aaggcaaaat
    16861 gcgcatcgat gtgccgatga gcgtcttgct gcatcgcctc gacgaagtgg tgaaagcgca
    16921 tgagtgttat atggccagtc agctcacgcg caacggcgtg acctaccggc acggacgcgc
    16981 gcggctgctc tcgccccacg aagtgcagct ggaaaccgtc gatggcgcct gccaaactct
    17041 caccgccgaa acgatcgtgc tcgccacggg atcccgaccg tcgtcgattc ccgagattcc
    17101 ggtggaccat gaacatgtgc tggatagtga ttcgatcctg tcaatgattt acctgccccg
    17161 ttcgttgacc attctcggtg gcggtgtcat tgcctgcgaa tatgcgtcga cttttgccct
    17221 gttgggcgtc gaggtcacca tcatcgaccg agccaaacgt cccctcccct tcatggatca
    17281 cgatatcgtc gacgtgtttc agcgcagcat cgagcgtcaa gggggacggt tttattccgg
    17341 ccatacggtc acagaggtgg cctgggatgg tgtctcgtcc gtggtggccc ggctcgcgaa
    17401 cggtatggca gtcaaaagcg aaaaaatgct ggtggcgctg ggccggcaac cgaatgtcga
    17461 ggaattgaat ctggaggcgg cgggattgtc gctcgatgaa aagggacata tcccggtgaa
    17521 cgatcacggg cagactgcag tgccgcacat ttttgcggcc ggcgatatgt tgggccgccc
    17581 gcccgccttg gcttctcagg ccatggaaga cggccgacgc gctgtcagcc atgctttggg
    17641 tctgccggtc ggagattcgc tcaatcaggt gcccatcggc atctatacga ttccggaaat
    17701 cgcttccatc ggtctcgatg aggaacaggc ggcggcccgt taccggggtc cgatcatcgg
    17761 ccgcgcgccg tttacggaaa ttgctaaggg ccagatcacc ggcgcctgcg acgggttgtt
    17821 gaaacttgtc tccgatccct ccggcgaacg cctgttaggt gtgcaaatcg tgggcgagaa
    17881 tgcgacggaa ctgattcatc tcggccagat ggctctgcag gatggggcga ccatcgatcg
    17941 gttcatcgac accattttca gctttcccac gtttgccgaa gcctatcgcg tcgccgccct
    18001 cgacattctg ggccagcgcc gtaaacggcg ggacgaggct caagcagcct gatcgtccat
    18061 ccttctctcg ccgcttcctt tgacccccgt cccccatctg cgctactctc tccatcggcc
    18121 ggtcttccga tcgatggagg ttgtacatga atcgtgagga gcgtcgccgc gaagaaaagc
    18181 tacaggggcg caatgccgga ggcccggcag cggcgttggc cgggttgcgc gaggcccaga
    18241 tgcatcatca ggccggccgc ctggatgacg cagaacgtgg ctatcagcag ctgctggcac
    18301 ggatgccggc gcagccggat gccctccatg gtttaggcct gctgctgtac cggcgcggca
    18361 atctccgtga cgcgctcact cgcctggccc aggcacgcgc ggccgatgcg cgcaatcccg
    18421 tctactgttt caaccatggc gtcgtgcttc aacgagcagg gcttctccct gacgcagttg
    18481 atgcatacaa tcgagccatt cagctcaacc cccggtacat cgacccccgc acgaacctcg
    18541 ggaacgtcta taaagagtta gggcgcctgg cggaggccca agccacctac gaacaggtgc
    18601 tggcgctcaa tccggatcat gccgaagcgc acaacaatct tggcgtcgtg ttgaaagaac
    18661 aaggccggct cgatgccgcg gccgatgcgt accgcaaggc catcgcgctg aaaccggcgc
    18721 atgccgaggc ccacaacaat ctcggattgg tcttactgga gcagggcctg gtggatgacg
    18781 cgatccgcag cttcgagcgt gcgctgcagg cccatccggg ctacgggacg gcactgtaca
    18841 atctcgggat cgcgtggatc tggcgggaag atattcctcg cgcgctgcac tgctttgcgg
    18901 aaacggccaa ggccaagtgt gcacacggcc gccccgtcac cgactccgcg gtctttcggt
    18961 cgcgtgtgaa gcacgatgcc gagcaaatcg gctacctgtt tgaacgcggg ttaatcggcg
    19021 aggaatggcg cgggtatcat gacgcgcttc tccagttgtg cgggcgtctc gagccggccc
    19081 ccggcaccgt ctcagccaat cgtgttgccc tctcccctgc cgaccttcag cctatcgctc
    19141 cttcattcaa ccggctcctg tacattgcgc cttgcgacac gattgccgaa ggggcgctgg
    19201 cgccggatct tgatcacgcg gcgatcgaag cacggtatct ggcgacgcag ccggaggtga
    19261 cctacatcga tgggctcctg tcggaggaag ccctgcggcg tttgagagaa ttctgctgga
    19321 cgtcgacgat ctggaagaag gactacgaga acgggtacat cggggcgttt ctcggcgacg
    19381 gctttgcgtc gccgctgttg ctccagattg cggaagaact tcgccggcgt ctgccgcgta
    19441 ttttcggcac gcatcgtctc acccaggcct gggcgttcaa gcacgatagc gcccggcgcg
    19501 gattaaacat ccatgccgat gccgcggcgg tgaacgtcaa tttctggatc acgccggacg
    19561 acgccaatct caatcccgag agcggcgggc tggtggtctg ggacaaggaa gccccgaggg
    19621 agtgggactt caaaacctac aatagcgaca aggcgcgggg cagcatttac gagtggctca
    19681 cgtcgcaagg ggcgaaggaa atcaagattc cctatcgggc caatcgagcc gtggtgttca
    19741 attcagatct gtttcatgaa accgacgaca ttgcgttcaa ggaaggactc accaaccggc
    19801 ggatcaacat tacgctgctg tacgggcatc ggcatcgccc ttgagcagtt tttcgaaatc
    19861 ttcggcgcaa acagggcggc tgaacagata tccctgcacc tcatcgcatc cttcttcccg
    19921 taacttcgcc aactgacctt ccgtctccac gccttcggcc agcaccgaca gattcaagct
    19981 gtgggccatg gcgatgatgg cgcgcgtgat cttcacattg ttctcgttcg tcagcaaatc
    20041 ccggacgaag gattgatcga ttttcaaacg gctcagcgga aaccgttgga gataactcaa
    20101 cgaggaatac ccggtgccga agtcatcgat tgagaggcgc acccccatgg tccgcagccc
    20161 ctccaacatg gtgacggagg cttcgacgtc ccgcatcgct atggactcgg tcagttcgag
    20221 ttcgagttgc gcgggattca agccggagtc ccgcagcgca tcagcgacgg tggtaggcag
    20281 cgtacgcccg tggaagagcg agttggagac attggccgaa atggtgatcg ggggaagtcc
    20341 cgccttttcc caggccttga cctgacgaca ggcctcccgg agcacccatt cgtccatgga
    20401 gcggatcaag cccgtgtcga tggcggcgtt caagaacact cccgggggaa ccaggccgcg
    20461 cttgggatgt ttccatcgca ccagcgcttc ggctccgagg atgcggcgcg agtgaatatt
    20521 cagtttcggc tgatagaaga cgacgaactc ttcccgttcc agcgcgcgcc gcagttcgtt
    20581 ttcgagatcg aggcgttcgg ccgccgcggc attcagtccc gacgaatagt actggcaatt
    20641 gttccggccc tgttccttcg catggtacat ggccgtgtcg gcgttcttca ggagcgcctc
    20701 gaccgtggag ccgtccgatg ggaagatcga aatgccgatg ctggcagaga taaagatttc
    20761 atggccctcg atgctgaacg gatgggccag cgattccagg attcgccggg cgaccctgcc
    20821 tgcatcttcc ggctgcggta aggccgttaa caggatggtg aattcatctc caccgagacg
    20881 cgcgagggcg tgcatcggtt cctggtcggc atggcgactg accgagtcac tttgccgaac
    20941 cgattcgctg agacgttccg cgacatgtgt cagcaaccga tcgcccaccg tatgtcccag
    21001 cgtgtcattg atgatcttga agcgatccag gtcgataaac agggtcgcca gatgctgctg
    21061 gtggcgcgat gcataggaga tggcattcga cagacgatct ttgaacaaca cgcgattggc
    21121 taggccggtc agactgtcgt aataagcgag ctgatgaatg gcccgctccg cttgcttccg
    21181 ctcggtgatg tcctgggccg tcccgatcac ggtgatttcg tcggtctctt cttcgcgcac
    21241 gccttcggct tggagatgga tcacgaagtc ggtgccgttg ggcagtacga tgcgatgatc
    21301 gatatcgcag ggcgtatgtt gcgcaacgag tttctgcaac gcacccgtca cgatcgaacg
    21361 atcgtccgcg tgcacgaggg cgagaaacgc ctcgaaggta ccggcaaaat cctgcggccg
    21421 caccccgacc aggcggcaca attcattcga catggcgaaa cggttggtct tcggattcca
    21481 gtcccagttg ccgatgcgag cgatgcgttg cgccagttcc agccgggatt cgctgcggat
    21541 caacgcgtgc agcacgttat tggtgcgaag catgtatcgg acgtggtggc agagaatcgt
    21601 ggcattgacc ggtttggtga tgaagtcggt agcgccgtgc tggtaggcct gtccgatgga
    21661 ctgcgcgtca tccaggccgg tgaggaccag aatgggcact cgtttgcctc gcggaagcga
    21721 gcggattcgg gaacaggtca gatatccgtc catatccggc atcatgatgt cgagaatcac
    21781 gagatccggc ccgatggctt caaacttcgt cagcgcgtct ttcccgcccg tcgcctccag
    21841 gacgatcatg ccggccggtt ccaatgcgtt tttgacgaac agccgggcga gtggatcatc
    21901 gtcggcgatg aggattttgg gagtcgtttg actcatatgg tgtctggcct ataagtctcg
    21961 cggtcggttg attcgcgtcg ccgctccggg gcacaggcct tgtgcgagca gtggccggcc
    22021 tgccgattca gcgttcccca cagcctatca aactttggaa gaactgccag agaattagca
    22081 cttgtcgagc atctcgcgtg caggtcgaat tcgtaggtga aagcctgaga ggaacggtat
    22141 agccggaatg gttcaggttt cacgccatct cgcctctctc ggtcgtgtcg aggcccccgg
    22201 gtatcgtgtg agggccttgc tctctggctt cgaggacaat gccggccaag agcgtgcgga
    22261 cccggctcat caggccgcgc atcgtcagca tcagaagagt tgcggtcaac agcagcagcg
    22321 gggcgatcac cagggcgaca tcccggccta aatcatcgtc cgatcgggga gcggccgctt
    22381 caggcggtgt cgcgacggcc agtcgtatcc aaccagccac ccggttgtcc cggcggaatg
    22441 gttccatgac gatgaaggca gctctcccct gttcgatacc agacgtgatg acaccgcttt
    22501 gtgtccggcg tgctgccagc gaggccgcgt cttggagcgt ggttccaatg gcggcgggat
    22561 tgctcgatgc gaccaccaca ttgttgtcca tgatcacggc cgcggcgagg agattggcct
    22621 gctgagcatg ttgctccagt gtctgctgga tggagtcgaa attatcgccg cccatcgatt
    22681 cgctgaacca ggccagggtt tgcgccgtgg ccctggcgct gtactctgcc gccatgacgg
    22741 ccgaagcatt ccgctgcgcc acgagggagc ggtcatgctg agccaacagc acatagaggg
    22801 ccgcggcgca caatgtggaa atgatgatgc tgaccagcaa cgccgggagc caggtccgag
    22861 gcaatcgcga tgcggaagcg tcagccatgc tatatcctcc tcgacaggaa ggggcgctag
    22921 gcgccggagc cttcctacgc gtcctgagtc cgttcgtagg gatggcgagt gagtgctttg
    22981 acgatccgtt gaagccgggc ccattcgtca ggcggcaggg actgaaattc aagaccgatg
    23041 cggccgtccc ggcaccagcg taccacggct tgctggacgg tcagcatggt ctctggatcc
    23101 ggaagatgaa tgcggagggt cagtgtggtg ccgggatgca tggcggtctg actgacgatc
    23161 ccgcatcctc gcaaggagag atcgaccacg gtgccgtctc cctcgacgcg attcactgaa
    23221 ctgaaggcac ttcggaagtg agcgggaaac cgttcgtgct ggcgttgttc catcgtgagg
    23281 cggcgttgag tgaatgacga cacgctctct gtgctgcgtt ccccggaagc cgcgcatgtg
    23341 tgtcgaatgc atgccgtgct agccctttat attgccaatt ggtttgagtt ccgccacttt
    23401 ttttgtgatt cccgcctggt ccaccgtgtt caccacgtcg gaaatgttct tgtaggccag
    23461 tccggcctct tcagcgaggc ccgacatcga cacagccttg accagaatac cctgttgttt
    23521 catgtcgcgg agcagttgtt cgccgcgtac cgagcgtttg gcctgtgcgc gggacatggt
    23581 gcggccggac ccgtgcatcg tggagccgaa ggtgtcatgc atggcgcgat tggttccgac
    23641 caggagatag gagccggttt ccatcgagcc accgcaaatg accggctggc cgatcgcgcg
    23701 ataacagtcg ggcagttccg gactccccgg cccgaaggcc cgcgtggcgc ctttgcggtg
    23761 gaccagccac tccccgtctc cgtaacgctc caccttcgcg atgttgtgtg cgacatcgta
    23821 gatcagatgc atgccgagtg catgcggggt ggaatcgaac acggcggcga aggcttcgcg
    23881 gatttgatgg gtgatgacct ggcgattggc aaatgcggtg ttggcggcgc agttcatcgc
    23941 gccgaaatac tcctgccctt ccggtgaacg aaacggcgcg caggcgagtt gttgatcctt
    24001 gacggagatt ccgtagcggc gcatcgcctt ctcgaagact ttgaggtagt cgctcgcgac
    24061 ttgatggccg aatccgcggg agccgcagtg gaccatcacc acgacttggt cccggccggt
    24121 caggcccatc gcggcggcgg tctcccgatc gaagatgttt ttgtctgaga cgacctgcac
    24181 ttccagatag tgattgcctg atcccaatgt cccgagttgg ttgatgcccc gttcgatggc
    24241 gtaatctgtc acatgcgccg gatcagcgcc gtcgaggcaa ccccgttctt cgatccgttc
    24301 caggtcctcg tcccacccat acccctttgc gacgcaccag acagcgcctt tgcgcatgac
    24361 ctcccgaaac tcgcgccggt tcacgttcac gaagccgcgc gatcccaccc ccgccgggac
    24421 gcggcggaac aactcggtca tcagcagttc cagtttcggt tgcacctcgg cgcgcgtcaa
    24481 atccgtgcgg atcaaacgca tgccgcagtt gatgtcatag ccgacgccgc cgggagagat
    24541 gatgccgtcc tccggatcga aggccgcgac gccgccgata ggaaacccgt agccccaatg
    24601 gccatcaggc atgcagagcg cataacgatg gatgccgggc agacaggcga cgttggtgac
    24661 ctgatcgaag acgccgcgat ccatggctcc gaggatggcc ggactcgcat aaattcttgc
    24721 gggaaccagc atgccaacct tctcggatgg cggaatttcc cagagatagt cgtcgatacg
    24781 gttcacctgc atgtcggtgt tgagtgtcat cggttcacct gtcaattgca caagaattgt
    24841 gagggatgtg gtcgttcatc agacatccaa gaccactctg gccttccaac tatttccggt
    24901 ttgcgtcacg gcatacaagt gtttggtgac acccttgatg tcggatcgga gatcctgcgt
    24961 ggcctgatcg accggggccc cgaccagttc tgcatggagg tgccaggcgg attgaccggg
    25021 cgctgcctgc accgtcaacg tggcatggtg aaagaccacg gcttgcgcgt ctttcaagta
    25081 cacgagccgg ttcagccatt caaagagcag cgtatcgatg tcaggttctt ccatgtcgac
    25141 gacctgctgc caggtctgcg caacggtagc aggatcggcc aggctttgga ggagcgcctg
    25201 cgttgcggca tcgaaaagcg acgcaagaga atcgccctcg gcctcgaagg ccatgtcggc
    25261 catcgcgatg tcgtcgagaa atcggaaggt gcccggcatg ggcgtcagac gcgcgtggtc
    25321 cgtcgtcggg ctgcagcgaa aattgcccgg acctgttcga tccctggaat ggtatggccg
    25381 aacggcaatg ggaccttacc tttgaaaaac atgcggaccc cgagcggcat gacatcgacc
    25441 acgcgttgca ggttaaatcc gagaactttg agcggcatca aggcctcgtt caaccgtcct
    25501 tcctggcgga cgaggtcgac aaagccggta atgtgacggg cgccctcggc agtggtcaaa
    25561 ccatgccgaa gcgaagaccg ccgcagccgg atgatcgcct ccatcggttg aacgtctttc
    25621 gggcagacct gcacgcacat gttgcaccgc gtgcaatccc agatgccgtc ggcttcttga
    25681 agcgcggcga gccgaacctg tttcgcatcc gccggttcgc gcgggtcggc cacgaagcgc
    25741 gccgctttgg cgagcgccgc cggaccgaga aagccgcggg agacttcatg ggaggtgcag
    25801 gcagcaacac aagccgcgca catgatgcag gcgtctacgt tgtgaaattg gtaactgtcc
    25861 ggcagcaggc gcagttgccc tgaggatccg tagcgtttgg tcgggtgcgt gatcggggta
    25921 agccagggcg tgaccgcccg gatcttttcc cagaagggcg ccatatcgac caccagatcc
    25981 ttgatgagcg gaagattcgg caagggagcg atgctgattc tgccatgccg ctccagttct
    26041 ttccggatgg acgtacggca ggccagcttt tgtgtgccgt tgatcagcat ggcgcaggag
    26101 ccgcagatcg ccgaacggca ggaatagcgt agcgccaggc ggccgtcgag ttcgttcttg
    26161 atgcggatca aggcttcgag caccgtcatg cctcgtccga tgtcgaggcg gtactcttcc
    26221 tggtgcggct gctggtcggt ttcgggattg aatcgctgga tcgtgaaggt gaggcgcata
    26281 acgttgtgaa cgtcgagatg cgaataccgt aggcggtaga cgcctaaccg agttcaaaca
    26341 ctttcggata gttcgtcaga ttccggcaac cgtctttcgt gacgagcacc atgtcttcga
    26401 tgcggacggc gccaagtccc ggatagtaga gccccggttc caccgtgacg acatggcctt
    26461 cctgaagcaa tgaaccggtc cggctgatcc gaggcgcttc atgaatgtcc agtcccacgc
    26521 cgtgcccggt gccgtggaag tagccttgca tgcgaccgtt caccaccccg gtcttgtagc
    26581 cggatttttc aaaccggtcg cagataccct ggtggatgac cgccccgtcg gccccgtcgc
    26641 gaattttggt gatggcttct tcctgcgcgt ccttgacggt ctgatacaac ttcttcaact
    26701 ctggagaggg ctgcccgcga accactgtcc gcgacatgtc ggcaaaatag cgggaatcgg
    26761 cggagcgcgg aaacacgtcg aaaataacgc tgcgatgcgc cggcaacggg ccgctgcctt
    26821 cgtcgtgcgg atcgcaggcc tgttctccgc cggccacgat ggtatgttgc gccacgcaat
    26881 cacattccat cagggccacg ttgatgagtt tcttcacgcg ttccgatgtg agcacctgcc
    26941 cgtcgagcca aaggacattg tcgcgaatct cggcgcggcg caagctctcg tgggcagcgg
    27001 ccacggcctt ctcggtcgcg cgctgggctg cttcgatgtg ccggacttct tcgtctgact
    27061 tcaccacccg gctttcataa aacggatcgc gtttcgtgcg tagccggtat ccaagctcct
    27121 ggagtcgttg cgcatggaga aagggaaaag tcggtggcac caggatatcg cggacgccgg
    27181 cgtcctgcag gaccagatgg atgacatcga tattgccggg atctttgacg ccctgtgctt
    27241 tcgcgcgtcg ctccagttcg gaataggaca ccacgcgatc aaccgtcgct tgatgccgcg
    27301 cacgatcgac ctccagatca ctcatgatca tcagccgctc ccctttcacc tcaaggtaga
    27361 tgaagggatc cggcgcgatg aatttcgtcg cgtaatagag attggaatcg gtttcgctgg
    27421 cggcaatgaa gactgtcgcg ccggggacgg gattcgtatg ctggtcggtg gaatggctca
    27481 tgaggtcgag gcgatctaat caatcggatg ctatcacgcg ctccggaggt ggtcaaggcg
    27541 cggccggcgc cgtcgcagcc ggaacatcga caggcggcgg tgcggagggc ggtgtttgaa
    27601 tttccaatga cggatcgaac agcggctcct tctcctcttg cggtgcaaga atgtcgatcg
    27661 gcagcatgac cgtattcttc agcaggtcga aggcaagctg cgccacgccg gtcagacccg
    27721 tggtaaagga cttcatcggc atgtacgtga cctgtggatc atcaatcgac cccttcacct
    27781 ggaacagggc cgtggcgaga cctttacgat cccctgccac caaccgcccg aagagcggaa
    27841 tcgatttcaa gaattgtgag tatgatccga acgggctgac cgcccagatc atgtcgagct
    27901 gatccgtggg catgtcgtag gtgccgacgg ccgaaatctt cagcaccgcg ctgtccagaa
    27961 taatgttctg cgttttgacg agcccgtttt gcaccgtcag cgtggcgctg gcgcgattgt
    28021 actgcaggcc ttccttttcg aggtccactt tcccttgcag gacggcgggc agattcagga
    28081 tggagaggat tttccagatg gcgcgtttct ctgttttgag aatgcgtcca tcctgtagca
    28141 cgagttccac tttgccgttg agtgtcggca gcactccatg aggattgcgt ccatgtccgc
    28201 gcagcgcccc ggtcagtttc atatcgccgg tgacgggctg atcgtgcgca cccaacaatt
    28261 gcagcacggc ctcggcggga atgcccgtca tacggacaga ggattccgtt tcagccggtt
    28321 ctcctttggg aaggcgcacc accatccgcc ctgccgcatg tcccgttccg gattgtgcga
    28381 caacccggtc gagatccaac atgccgtcct gaatggtcaa ccggcccgac aatcccccga
    28441 accgcaaatg tttgtagagg cccttttcaa tcgtggctgt cgcgctgacc tgactcgtgg
    28501 aggcgagtgt ttccaggaat tcccggatcg gtgagcgatg gcccttcggg atgagcagat
    28561 ccaggtccat ttgcgccgac tcgattttga ccgcgatcac cggcttggtc gtccaattct
    28621 tcagggcgcc ggacaggctc acatcgctgt ccttgatgcg gaacgaaagc tgtttgatgt
    28681 cggcgatgtt tttggagaac ttcaagcgaa ggtagatgtc ttctaccgcg ccgtccacgc
    28741 ccttgagcgt catcaggcca ttggtcagcg ccagccagcc gccggcgcgc cagtttttcc
    28801 actcggcatc cgaacctttc acgtccatgg acacttcgag attgccggct tcgaagccgc
    28861 tgcgatacac ccagtcggga agactggaga ccgataccgt gccggtggcg agcgacgcgt
    28921 cgatggaaaa ctgatcgccg agggtaatgc gtcccttcaa cggcagccgc aagggcggca
    28981 cgaccagttc caggcgagaa atcaccaggc cgatgccttt gctgacgtca gcatccagtt
    29041 ccagggaggc cggcgagccc aacggttttt cacccaacgt gggtagcacc agtttggctt
    29101 cattcaggcc gatctctccg cgcaagtgtg gcgccccgga cggccccgag agctgcactc
    29161 gcgcattgac catgccatag agcaggtcgt cgggaaaggt gcccgccgat accatctgcc
    29221 gcagctgcga ggcgctgcct ttcgcgcgga tcacgaaatc ctgaaacacg ctcggcgtac
    29281 ctccgctgat catcccgttg aattgcagct gggcttcccc cacgttggcc gtgacttgat
    29341 cgaactgcgc gccgccggtt tgcgagaaga cgatacggcc gcgcatggcc gtgaggcgtt
    29401 gcggcagcga gggattcatg aggctgacct gttcggccag cacctccccg cctgcgaagg
    29461 taatgccttc gggtttgtcc agcgggccga ccagccggaa cgtcggatgg gtctggcctt
    29521 caatgtcgcg ggactgcgcg agcagcgagg tgagcttgtc cgcacgaatg gtcttggtga
    29581 gaaacttcac caggtcggcg gcgctcatgt cgccactcac atccagctcc atccaggggc
    29641 cgtcatcgag gaatgacacc agggctttgc cgtcggtgat ctgcagtgag ccgtaggcgc
    29701 ccgtcacttt gccgacccgg atgcgtcccg gttccactga cacggttgcg gccaggttct
    29761 gcgtcggcac gcgatcattg ccgatcaggg ccatgccctt atcaatgcga aaatcacccg
    29821 tcaatgacaa ctgcgggctg ggcgccgtgg cgcccgtcaa ggtcgcggag agaatctcga
    29881 cggtgccgcc caattggcgc tgctcgatga tggcaggcag ttgggcatga atccattgcg
    29941 cgggaatcct tgtgaagagc gagcggagat cgatcgatgg cgccgcgaag gtaatggaaa
    30001 acgtcggctg ggaagtgagc agtccggcca gattggcctt ccccgtcacg gccagttcat
    30061 ccacgttggc agcaatctcg gacagcacga catcatagcc ggccacgccc ggcgccaccc
    30121 ggatgcggct ttggagactg gcccctccct gcagttgcgg gggaaccggc cttggcccga
    30181 agaaatccgc cgcttcccgc aggcgaagat tcgtggtgtc gatctcgcct tcgaattgaa
    30241 aggccgggcg aacggaatag ggttcctcgg ccgccagcgt cgaagacgat tcactcaatc
    30301 cgatcgtgcc ggtcagagaa aacgaagagg gcgcgccatt cgccggcagc gcggcggaaa
    30361 tatgcagatc cccttctgcc ttacccggat agaccttcag cgccatctcg accgtttcga
    30421 gcgtcgtcgt ccgcacgccg tccggccgtg cctcatccgt caccgtgatg tgccccttct
    30481 ggatggtcgc ttcacggatc tgcagcagcc ggctgaacat ctgatacgcc gactcgtctt
    30541 tcgccgccga gggcatgccc gccaggacat tccaatggcc cgatcggttg cggacgagcg
    30601 tcacggtcgg ttcgttgaga aagatgcgct tcgcgacgac ctgctttttc agcagcggca
    30661 gcaggcgcag gacgatatcg atttccttgg ccgagaagac gacgtgtgtg gggtcgtcgt
    30721 ggccgtaaat gccgacgttg gtgagctcca ggcgaatgct gggcagcacc acgagtttga
    30781 tgcgatcgac ttcgatttta cggcgaaggc tggtttcgag ttgctggagg aagaagttct
    30841 tgaggatgtc gacgccgaac agttcgcgcg agtagaagag aagcaggatc cccgcgacca
    30901 ccaggccgag cagcgacagc actaccgtgc ggggacgaac cctcactgac cctcctctaa
    30961 gtagagcaag aacgcagtgt actggatgcg tacgcgggaa atccatacac aggcgtgcgg
    31021 cagaggcgca aaacctgagc gagacacctc ccatgtcgcg gtgcctcgcc tttcacattt
    31081 cagtcgtgcg tgtacggggc tataatgcgc cggccgctga acggcgggac actgggggaa
    31141 tcacgagtgg ggctcgacac atcagcggtg cgaccacgtt ggggcattct cgctctactg
    31201 ttcgcgatca gcgccgtcac atacatggac cgggtcaaca tttcggtcac ggcccggcag
    31261 atgatgcctg cctacggact caccgaccag gacatgggct acgtcttctc ggccttcgtc
    31321 ttcggctacg cactctgcca aattcccggc ggacgcctgg gcgatcgttg gggagcacga
    31381 gtggtgctgg cttgtgcctt gctctggtgg tcgctctgta cggtgttgac cgccgtggtg
    31441 gccaccctgc cggtagccgg tctggtcggc acggtcggcg cgctggtcat cgtacgattc
    31501 ctgctcggcg tgggcgaatc ggttgccctg ccgaatttca atcgtgctgt ggctgactgg
    31561 atgccgccgg gacagcgtgg gcttgggatc ggcatcgcca tcgggggcat cggcatcggt
    31621 gcggccatca cgcctcccct cgcctcctgg gtcatggtga actatcactg gcaatcggtg
    31681 ttttatctct cggccttgat cggtctgatg gtggccttgc tgtgggtgct cttctcgcga
    31741 gatgggcgga gcgacgcaac ggcaaaggcg gacaccattc cgacgccggt cccctggggg
    31801 acaatcttcc gctcccggcc gctctggtgg ctcgtcgcga gttacacctg tctcggctac
    31861 gtcgcctata tctacatgag ctggttttat ctctacctgg tgaatgtgcg cgggatcgat
    31921 ctcttgcgcg gcggctggct ggcggcagga ccctttctgg caatcctgct cttctgcccg
    31981 ctcgggggat gggtcacgga caagctggtc ccgacgatcg gattgcgcag ggcccggctt
    32041 tccatcggta tgctcggcat ggcgttggcc ggtggattga ttgccgttgg tgcatgggtg
    32101 gaatctcaga ccttagcgat cgtctgcctg tcgctcggtg ccgggtggct ctactttacc
    32161 gtgggcgcct attggagcgt gacaacggat ctctctaaga cccatgccgg gactctctct
    32221 ggtgtgatga atacgggcgc taacgtaggc ggcgtgattt ctccgagcct cacgccctgg
    32281 ctcgcggatc actggggctg gacggcgtca ctactggtgg ctgctggtat cgcactctgc
    32341 ggagggctca tgtggatgaa ggttaatccg gaggatgggt tgagggaatg agttcttccc
    32401 ctcaatgttg cattctcatc tgctatctcg cttccccgtg ttccttgaga aataaatccc
    32461 gatagcggct cggttggctg cgccaatatt gtttcggggc cttcacctga cctcccagat
    32521 gggctgcagc gtgccacggc cagcgcgggt cgtagagaat ggctcgtgca agggcgatca
    32581 tgtccgcatc gcctctgctg aggatctctt cggcttggtc gtagtccgtg atgagaccga
    32641 cggcaatcac cggcatggac accgcctgct tgaccgcacg agcaagggga acctggtagc
    32701 cggggccgac tggaatctgt tggcgcggat cgagcccgcc gctgctgaga tgaatccctg
    32761 cgcacccccg tgcttccagg gccttggcga acacaatggt ttgctcgatg tcccagccgc
    32821 cttcaaccca gtctgtgccg gacacacgaa ccgttacagg ccgatcagac cggaatgcgg
    32881 cacgcacggc atcaaacact tcgag
//
LOCUS       DAOQPD010000042        32891 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_596_length_32891_cov_22.046382, whole genome shotgun sequence.
ACCESSION   DAOQPD010000042 DAOQPD010000000
VERSION     DAOQPD010000042.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 32891)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 32891)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32891
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_596_length_32891_cov_22.046382"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..377)
                     /locus_tag="PK063_10995"
     CDS             complement(<1..377)
                     /locus_tag="PK063_10995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HMZ97624.1"
                     /translation="MPIHIAAAQPVDAPIIAKLVGDLLAEIVAAIKTAAFGFSLAETE
                     ARARAWLEDGSYTVLLARNGECAAGFIALAECRALYAEGRFGIIPELYVSPDRRSQGV
                     GGALVNEAKRVARSNGWARLEVTT"
     gene            complement(379..1995)
                     /locus_tag="PK063_11000"
     CDS             complement(379..1995)
                     /locus_tag="PK063_11000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006885 - regulation of pH [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter"
                     /protein_id="HMZ97625.1"
                     /translation="MDSLHQLEIIILLLAVVLALTTIAQKISIPYPIFLVLGGLVLGV
                     VPGLPTVTLHPDLVFLVFLPPILWAAAYFTSLREFRQNLRPISLLAVGLVLATTAGVA
                     VVAHALLPGIGWAEAIALGAIVSPPDAVSATAIGKRLRIPRRVVTILEGESLVNDATA
                     LVLYRAAVGAVVSGSFLLGGTLLNFLFAALAALAIGLAAAWLTRWALCVTEDGYTQIG
                     VTLLVPYIAWVIAESVHASAVLACVAGGITLRQYFSGAVAPATRLQARAVWELLIFVL
                     NGVIFILIGLQLGALRDAVPAGQYGPVVFAGLMVSATAIVVRFLWVPLAALIPRCLSA
                     TLRARDPMPSWKGLFLISWTGMRGIVTLAAALALPMTTGTGAPFPFRSEIILISFAVI
                     LVTLVLQGLSLPPIIRWLRLEDEDDLDREQRLAREHAATAALARLDEVMTEDWVPREQ
                     IERVRLRYLRRLEHLNRTGLNEEERPEGSVETVQRLHHEVLTAERVALIGLRDDGTIS
                     DEVLHHLEQELDVAALHQGVGERRAGKGRI"
     gene            complement(2028..2864)
                     /locus_tag="PK063_11005"
     CDS             complement(2028..2864)
                     /locus_tag="PK063_11005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HMZ97626.1"
                     /translation="MLTAYNQVPVPSFMYGTAWKKDATTQLVQQAVAAGFTAIDTANQ
                     LIHYQEALVGEALLALAKQGTPRERLFVQTKFTPVNGQDHRTPYDAQADLTTQVKQSF
                     GSSLAHLHTDYLDSYVLHGPYARRGLSDADWEVWGAIESLYAAGTTRMIGISNVSADQ
                     LRLLCERATHKPMVVQNRCYAALGWDRDVREICRAHGIIYQGFSLLTANRDIFSDPDV
                     RTMAAKYGMGLAQLVFRFAMQMGMLPLTGTTDQQHMAEDLRSDQFTISTEDLQRLETV
                     GM"
     gene            3012..3326
                     /locus_tag="PK063_11010"
     CDS             3012..3326
                     /locus_tag="PK063_11010"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97627.1"
                     /translation="MEAAQANQVVELRLTYRYIKDHPWTVQAINGFLSAYFMEKPGFS
                     VQRHYDDLESGMHVWICDIPANMKITVLLRRLQADIPPCRHLQPAVEPSARPQYVIDS
                     PE"
     gene            3396..4004
                     /locus_tag="PK063_11015"
     CDS             3396..4004
                     /locus_tag="PK063_11015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="short chain dehydrogenase"
                     /protein_id="HMZ97628.1"
                     /translation="MRVIVIGGTGTIGSAVVKRLSTRHEVVVVGHKKGAFQVDLASPD
                     SITSLFKAIGTCDAVVSTAGIAKFASLDDLTYDDYFIGLKNKLMGQANLVRIGRPFVT
                     DHGSFTLTSGVLSQNPMKGSASISMVNAGLEGFVRAAAIDLPRGLRVNVVSPPWVTET
                     LIARSMDPSIGIPADQVAQAYVASVEGSMTGQTLDPRQIAAT"
     gene            complement(4021..5136)
                     /locus_tag="PK063_11020"
     CDS             complement(4021..5136)
                     /locus_tag="PK063_11020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HMZ97629.1"
                     /translation="MAEPLKNSFGADVPRTIARMIAAVSPRFDEKAFVRSVLDGYDEL
                     ELMPRAWKIAHVLRRHLPDDYERALEMLLASLDQQSKRKTASGMGAFLFLPHVFFVAE
                     YGLDHFEASMRAQYVLTQRFTAEFSIRRYLERHQAATLARLAEWTADPSEDVRRLVSE
                     GTRPRLPWAPRLRAFQADPRPVLALLERLKDDPSLYVRRSVANNLNDIGKDHSEVLVE
                     TARRWLENATAERRWIIRHALRSAVKRGEAGALHVLGFGHTPLVAVETIRIAPSRPRI
                     GSSVGVTWEVANQASGGQRVLLDLRVHYLKANGKHSPKVFKFKTVELAARETLRFSKS
                     LALTQLTTRTHYPGLHRIELLVNGHAYPLGVFHITAG"
     gene            complement(5143..5535)
                     /locus_tag="PK063_11025"
     CDS             complement(5143..5535)
                     /locus_tag="PK063_11025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor"
                     /protein_id="HMZ97630.1"
                     /translation="MKEKTRIPTDGEPVTWKSPFAALKDVVLPPAPPREQAKQLGTPA
                     PAPAKNRGRVDIIRQTAHRGGKTVTVVTGFVGISQTEKEQLAKEMQKACGVGGTVKEG
                     RIEIQGDRRDDIARILTKAGFRPVFAGG"
     gene            complement(5557..6108)
                     /locus_tag="PK063_11030"
     CDS             complement(5557..6108)
                     /locus_tag="PK063_11030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeQ family protein"
                     /protein_id="HMZ97631.1"
                     /translation="MAPNATICKAVLHIADVDRQYYEDHSITLARHPSETDERMMVRL
                     LAFARHAHEALSFGRGLSTEDEPALWQKDATGLIELWIEVGVPDEKTIRRACGRARQV
                     WVYTYGGRAADQWWKQHGAALDRLNNLAIVNLSLEGSRALTSLAQRSMDLHCTIQDGQ
                     VLIGDGTNAAQMDLLLWKEPARE"
     gene            complement(6156..8474)
                     /locus_tag="PK063_11035"
     CDS             complement(6156..8474)
                     /locus_tag="PK063_11035"
                     /inference="COORDINATES: protein motif:HMM:NF013117.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HMZ97632.1"
                     /translation="MPIPLTLAFCFLLSLMQISAVSAQSTSSSTDKAVRATLETVGVK
                     LDQPAANGPAPDAAAADLQHKRAAAEKELSELTTPQAQRKGTAGNQVDGRTAERRSLL
                     QQLVQIYEQHLDALRNLEQMRQRVREAERQEKEWDGFSTPAPYSVLKIDELRDAVRSM
                     TLASQGAQTRLNMTESLTESTQRSLKASQEKARQLSERLEEVQDPAKREALTGDRDLA
                     RLRERVEGARAGMLEAEKKQIQEEVAEARHRMALLTRQRTVAEQDSAFTQQDYDKIKK
                     RLDAEHQSLTDEIERAVLEQSTQRQAVAAGEAALAAANAKDSSSKRNASRPKGDRLTA
                     LTESVELKRLQFDNANLHVELLREMLTGLEQERHIWDIRFATAQETLSVVEEREANAK
                     IAAAAKQIRGWKEYGSQQLSMVGNHISDVEDRLAEAPSAARAQVFTDKLRLYRHREDL
                     YRRALQRTDSLLGLIDNKQAEFAHREQARSVFARMKEWGRASVVMLGNAWHVELFAAE
                     DTIEVDGKNITGRRSVTVGKVVTALAILIVGYWVAGIMARFAERQAIARLQIDPNVAN
                     IIRQWALACFFLLLVIVTLMSVKIPITAFAFLGGALAIGVGFGTQNLLKNVISGLLLL
                     MERPLRVGDVIEVDGIRGMVTTIGLRSSTIRDINGVETLIPNSNLLEKNLTNWTYSSF
                     RKRYSLRIAVATGSDARHVKEKLRELAGEHGQILKEPEPYVLFEDFSEHALVFVLHYW
                     IEISPGIDAATVASDLRFMIERTFAEEKIARK"
     gene            complement(8665..8880)
                     /locus_tag="PK063_11040"
     CDS             complement(8665..8880)
                     /locus_tag="PK063_11040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VF530 family protein"
                     /protein_id="HMZ97633.1"
                     /translation="MLNHPRDPLHGITLEKIVTTLVERHGWAELGRRLPVRCFLNNPS
                     VKSSLTFLRKTQWARERVEGMYIAELE"
     gene            complement(8949..9698)
                     /locus_tag="PK063_11045"
     CDS             complement(8949..9698)
                     /locus_tag="PK063_11045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HMZ97634.1"
                     /translation="MNVDDIISYGELVSAEKLMLQKGMNFGVGKDYSILLMSQRANAP
                     YRDVVDDATGILIYEGHDQPRTKDCPNPKTVDQPMTTPKGTLTENGRFFRAATDFKHG
                     LREKAELVKVYEKIAVGVWCYKGFFELFDAHLISRLEKRRVFQFFLKPVQKKAFGRIG
                     ELSHKRLIPTHVKVEVWKRDQGKCVQCGLQENLHYDHDIPYSKGGSSLSAQNVRILCA
                     KCNLQKSNRIMGVFPWLWVASSRLLELGWHP"
     gene            10010..11638
                     /locus_tag="PK063_11050"
     CDS             10010..11638
                     /locus_tag="PK063_11050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HMZ97635.1"
                     /translation="MSLPVEKSASDELRREVLRRRTFAIISHPDAGKTTLTEKLLLYA
                     GAVHLAGAVQARSTQRQAKSDWMELEQARGISITSTMLQFDYQGARVNLLDTPGHQDF
                     SEDTYRTLMAVDSAVMVLDGAKGIEPQTKKLFAVCRKRGIPILTFINKMDQPGRHPFD
                     LLDEIERTLGMTAVPFNWPIGEGSGFQGVYDFQNRQVLFFQRTSHNQRRAPMTVEAFP
                     NPKLAETLGDAYGPLQEEIGLLTGAGTSFDRDRFLAGELTPVFFGSALTNFGVGPFLD
                     AFTKLAPPPGPRHSAQGLVQPTDETFSGFVFKIQANMDPQHRDRMAFLRICSGRFEKD
                     MMVHHARLGRKIRMTRPHRLFGRDRETIDEAYPGDVVGLVNPGLFTIGDTLTSDPSLT
                     FDPIPHFPPECFGLLRTQDISKHKQFQKGLKQLEEEGVMQIFYSPDHVRREPVLAAVG
                     ELQFDVVMSRLENEYGVKTTVERMPHSLARWIVGDAATISAVYWPSDTVRLVDQQGRA
                     VMLFTTEHLLAYCIKSNPSIKFLLREEVEQATAQ"
     gene            11970..12140
                     /locus_tag="PK063_11055"
     CDS             11970..12140
                     /locus_tag="PK063_11055"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97636.1"
                     /translation="MPKARSAKNCYYCEAEDRIKMTFMLCGLCHRHFCSAHGVPDLEQ
                     CTKCLEASEETE"
     gene            complement(12311..12880)
                     /locus_tag="PK063_11060"
     CDS             complement(12311..12880)
                     /locus_tag="PK063_11060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ97637.1"
                     /translation="MTGKKGKRPVSAAAKISRKKVGMKVVKKAAPRKQAPARRAKVTR
                     TNKSSVAVVVLSGSTPLRRNKAAELVAEELQLDLSKVNLSSVVSQRVGETEKNINRVF
                     DDAERSGSILFFDGADALFGKHRPAKDGASHYANAGAAHLLQRIEDHNGLVILTTNGK
                     SRIDQALSKQARVSVMVGIEKKKRKQKTA"
     gene            complement(12963..14519)
                     /locus_tag="PK063_11065"
     CDS             complement(12963..14519)
                     /locus_tag="PK063_11065"
                     /inference="COORDINATES: protein motif:HMM:NF016724.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HMZ97638.1"
                     /translation="MNVRPWTAALRDWQARAVADVLAQKREDYLVTATPAAGKTRFAL
                     RIAHHYLAERAASRVLVVCPTNHLRTQWASAAGQAGIQLDPALSNEQACEARDYHGAV
                     VTYQQVCLAPDVFRRACRNRKTLVILDELHHAGDGKDWGKALRESFGEAVFRLALSGT
                     PFRSDNNPIPYVRYEQGESQADFTYGYSHSIRDGVCRPILFPSYEGELTWLSDGREHR
                     ATFEDGLTFERQRERLKTALLQETWLGPVLSDAHAELQRLRKQEQADAGGLIVTMNQD
                     HARQVADLVHRLTGTRALVAVSDDPSASKTIETFAHHKTQQWLVAVNMVSEGVDIPRL
                     RVGVYATNVLTEMYFRQVVGRFVRMQDKVPKPQRAWLYLPKDATLVHYAKRIKVERDH
                     VLEEIMPAVQRTLFGTAATSLKEYIPLNGVARLDALIGADEGEPSPAGKGHPEPAVAL
                     HDQKNQLRDKHRLLVGAVARKCGMDHRQLNAELIKRTGGRVDQATIPQLERRIALLEK
                     WRDSGFDKKR"
     gene            complement(14651..16063)
                     /locus_tag="PK063_11070"
     CDS             complement(14651..16063)
                     /locus_tag="PK063_11070"
                     /inference="COORDINATES: protein motif:HMM:NF012312.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HMZ97639.1"
                     /translation="MDRLPWSRWHWLVVTALGVTWILDGLEVSIVAALGPVLTHATTL
                     HLTASEVGLTASAYLAGSVVGAIVFSYLTDRQGRKKWFMFTLMLYLAATVMTAFSWNL
                     WSFMFFRFLTGAGIGGEYAAINSAIDELIPARSRGHTDLSINGSWWLGSAAGALLTIV
                     LLNPLLIPEYLGWRLCFALGAVLGVSILLVRRVVPESPRWLMTHGSVQEAERIVSGIE
                     AQIMRDEQLRALPAAEGSITIHGRTPATLATVARELFTAYPRRTSLGIVLMVTQSFMY
                     NAISFTYPFVLTKFYAVPSHSIGLYIVPFAIGNFLGPLLLGRFFDTIGRKQMISLTYA
                     VAGCLLASTGYLFFQGAFTSVTQTAAWSAIFFFASAGASAAYLTVSEIFPMEIRAMAI
                     AFFFVVAQGAGIAAPWLYGKLIETSAESVMYGYLLGAGMMVIGAIVELWLGVKAEGRS
                     LEHIAMPLSAQPVSSHAPHV"
     gene            complement(16254..17981)
                     /locus_tag="PK063_11075"
     CDS             complement(16254..17981)
                     /locus_tag="PK063_11075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HMZ97640.1"
                     /translation="MKHTTTPSPTEPAAKGFSPGFAALGLEASLLTTLEALGYEEPTP
                     IQREAIPPLLEGRDLLGQAATGTGKTAAFALPLLQRIAHGPRQRPTALVLVPTRELAV
                     QVSEAVQRYGKELRISVLALYGGQAMGPQLQALRRGVEVIVATPGRALDHLRRKTLKL
                     ADLQVVVLDEADEMLDMGFADDLDAILEETPATKQTALFSATMPPRIASIARRHLKNP
                     IEVTIAREPVKAGAAPRVQQTAYVVARQHKVSALARVLDIAMPKSALVFCRTRLEVDE
                     VTAALNSRGYRSEAIHGGMSQVQRDRVMQAFRTGQTELLVATDVAARGLDIPSVSHVI
                     NYDLPSSLEVYVHRIGRTGRAGREGAAMTIVEPREQRLLRAVEQHTKARITIAPVPSL
                     GDLLAKRLERTKSSIQETLEAGGLEDFRRVVDALSASADPADIAAAAIKLVYRSHGGD
                     REEEEIPAVQMRAPEPYRSSRPAYGSAPQGDRGRAPRGGPSRGGRAAGTVRVYVGAGR
                     AAGIRPGDLVGAIANEAGVPSRMIGAIEVEERFSLVDVQEEAARQIIEALGRTRIKGQ
                     KVAVRLFRD"
     gene            complement(18011..18697)
                     /locus_tag="PK063_11080"
     CDS             complement(18011..18697)
                     /locus_tag="PK063_11080"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic pyrophosphatase"
                     /protein_id="HMZ97641.1"
                     /translation="MSKKEIDAARRLMSLMFKAHPWHGVSMGDQAPDLVTAYIEIVPS
                     DTVKYEVDKATGFLKVDRPQRFSNFCPVYYGLIPQTYCGEQVAKLFGARAGRPDMIGD
                     GDPLDICVLTEKAIPHSDILLTARPIGGFSMADGGEADDKIIAVMRDDAVYGTLTDLK
                     ECPMTLLDRLQHYFLTYKQAPGSTAHNKVEITSMYGRDEAIKVIHASHDDYKAKFPEL
                     EFMWPASMNS"
     gene            complement(19007..19591)
                     /locus_tag="PK063_11085"
     CDS             complement(19007..19591)
                     /locus_tag="PK063_11085"
                     /inference="COORDINATES: protein motif:HMM:NF024895.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HMZ97642.1"
                     /translation="MGRIRHCVVSGKVLLLALVLSVAPAICQAAEWVHEGMADEGKMT
                     FGFRVGPSFMTQSSGLSTTGPALNFQGMYGINKWFRFGMMLEWENHSIDGPRNGSLNT
                     ITLLPVNLEYRPGHFGALIPYVTSGIGVNINTKDQADSFAWRFGAGLDYPMTSLFQGA
                     PKGLMLNMETAWKRNSADGDGSSMGLLFGVRHTF"
     gene            complement(19978..20628)
                     /locus_tag="PK063_11090"
     CDS             complement(19978..20628)
                     /locus_tag="PK063_11090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97643.1"
                     /translation="MRKVIHACSVLMLSVATVACAHTTDTPAPVASSAAGHQAKVAET
                     KAALRDLWLGHILSIRNVAVATMDKNAAARSAAEADVVANAQQIARSIEPFYGKPAAD
                     QLFTLLAGHYQGIREHLDATVAGSTSQQDAAVKALTANAAEIATFLSGANPNLPKDTV
                     MGLLMAHAAHHLTQFQQLKDGEYAREAETWKGMKQHIYVVADALTQALAAQFPAKF"
     gene            complement(20762..21502)
                     /locus_tag="PK063_11095"
     CDS             complement(20762..21502)
                     /locus_tag="PK063_11095"
                     /inference="COORDINATES: protein motif:HMM:NF012257.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HMZ97644.1"
                     /translation="MGSMIHTAMNMVDHRHCLALSGCFRGKLCEQLMNRPGRHMPKGS
                     RVYGPGDPAQSVFYLRRGFVKLTSLTEDGRELILRLHQTGEVFGELCHCTGERREQAI
                     AMEDSEIVELSFDEFIAHLQSNRPAFLLFLSNVAQQLSAAYDQIQTLSFNSTMERLVR
                     TLGRLADEFGEPDGEWIRLTHYFRQDDLAQMIGARREVVSTLLNQLREQGLITYARKD
                     GVLLRRAELDRFLGSTAQSSASLADSGF"
     gene            21652..22464
                     /locus_tag="PK063_11100"
     CDS             21652..22464
                     /locus_tag="PK063_11100"
                     /inference="COORDINATES: protein motif:HMM:NF012264.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HMZ97645.1"
                     /translation="MPAFLTATARSGRLGIASVGGLCLAISLTAGPLLWAGSSSPTKP
                     GNGPQEAEQGRVLFNGKGLCSTCHGVDGHKGQLPPHLTQHIRDNIAHLDPAPADLRQA
                     RTLTLTTDKQRFEIIRHGHLRTAMYPISKDTISDEEILALLPYLASIRGAVSPPASVP
                     ASSFSLRGDANNGRQLYHELGGCAICHGIEGHLDSRPPMSADLISRLKALPHPPADLR
                     HPSSLTAQSDEDLYRSIKLGHPGTAMYPKTLLRDEDIRDLIAYLAVLRGGSQ"
     gene            complement(22619..23011)
                     /locus_tag="PK063_11105"
     CDS             complement(22619..23011)
                     /locus_tag="PK063_11105"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97646.1"
                     /translation="MVEVNSMYQPRMRNDDIKAQIDKLEGLAHVTAVHPTFDTFDEET
                     ETILTRIFGGSHPYVESYKYATLGEAEAIVNLPESAQEPLTRDTPKKGLQQRRQVLQS
                     ILTDLQGLEAEEAEALTGEDHEDPPGPS"
     gene            complement(23118..23588)
                     /locus_tag="PK063_11110"
     CDS             complement(23118..23588)
                     /locus_tag="PK063_11110"
                     /inference="COORDINATES: protein motif:HMM:NF021425.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2127 domain-containing protein"
                     /protein_id="HMZ97647.1"
                     /translation="MLVSAPISQQTSLAPIALFKLVKGLLVLLAGSGFLRWIDPEIDS
                     GLSPVLDALHLNIHTRLLHALAITVDSLPRHSLLLMSLVSLGYAALLFVEGFGLWSET
                     SWAAYLTVVSTCVLLPGEFHAVVREWSMAGLAVLAVNIAIVGYLVRRLADETLR"
     gene            23692..24051
                     /locus_tag="PK063_11115"
     CDS             23692..24051
                     /locus_tag="PK063_11115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HMZ97648.1"
                     /translation="MNEQFARSLAEAWIDAWNRHDLEAILHHYASDVEFTSPFVPALS
                     GDPSGTLHGRDRLSAYFQKGLHTYPDLHFDLLQVLTGIDSLLLYYRSVKGLLAGEMMT
                     VNAEGLIQTVRVHYVKE"
     gene            complement(24088..>24913)
                     /locus_tag="PK063_11120"
     CDS             complement(24088..>24913)
                     /locus_tag="PK063_11120"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: protein motif:HMM:NF013375.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046316 - gluconokinase activity [Evidence
                     IEA];
                     GO_process: GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HMZ97649.1"
                     /translation="VCARRAVAAAAESWFAHRSEQVAQADAMAYLRRIQQHEAVPSAV
                     RQAAERLTTAVTRRHDTPFTTDPISDASLIIAHLAADTSTEECASGITPGQVGSSESG
                     PAITIDQPPLLIILVMGVSGAGKTTIGRRLAEVLGWRFLEGDDLHPIANIGKMRSGHP
                     LTDADRRPWLERLHAAIADQVRMNQPAVMACSVLKARYRTVVEEGFGHALRLVYLKGT
                     ADVFRERLAGRRNHFMRPELLDSQLAILEEPADALVVDAALPPDEIILRIRQGLAV"
     assembly_gap    24914..25013
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            25407..25565
                     /locus_tag="PK063_11125"
     CDS             25407..25565
                     /locus_tag="PK063_11125"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97650.1"
                     /translation="MMTQRLRKSSMYRFHDSVRHDRKYLIVALAAALILAAILASLGL
                     TVFPTFPK"
     gene            25657..25908
                     /locus_tag="PK063_11130"
     CDS             25657..25908
                     /locus_tag="PK063_11130"
                     /inference="COORDINATES: protein motif:HMM:NF013691.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HMZ97651.1"
                     /translation="MTWIVYILECADGSLYTGITNDLERRMRSHASGNGAKYTRHRGP
                     FTVRYTESLASKGAALQREAAIKALDRAAKVALITALQC"
     gene            complement(25944..26393)
                     /locus_tag="PK063_11135"
     CDS             complement(25944..26393)
                     /locus_tag="PK063_11135"
                     /inference="COORDINATES: protein motif:HMM:NF028108.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5069 domain-containing protein"
                     /protein_id="HMZ97652.1"
                     /translation="MDLPIRSPRQKLGEYVILPRLIDKVRLHAAGALPLDYVRNLLKP
                     GLTLDGRFLKFTGLAADALEGAILAAESDSLVLAWVDEQAIVHSDAEKQAWSEKAAAF
                     HPDPRVAKYLMMSLPDLATSLDITRYTLFDLIDMDEGRLPVPSRPKA"
     gene            complement(26494..27069)
                     /locus_tag="PK063_11140"
     CDS             complement(26494..27069)
                     /locus_tag="PK063_11140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ97653.1"
                     /translation="MAGATGTRQKKQAPQRKKAGPVKKTTRARAGQPSGAVIVLSGAT
                     PLRRQKAAEVLAEELQLHLAAVDLSAVVSKYARETEKNMTRVFDMANRHGSILFFDEA
                     DALFGKRTQVNDSHDRYANSEVSYLLQCIETHQGLVILATNGKSRIEDAFSPEKPVIV
                     LGGTAKKQAGVKPKPKAKSTPAPTKKVRKKK"
     gene            27324..28274
                     /locus_tag="PK063_11145"
     CDS             27324..28274
                     /locus_tag="PK063_11145"
                     /inference="COORDINATES: protein motif:HMM:NF037660.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ97654.1"
                     /translation="MIGFWFLLLWCLPAQAWAVSPGDVTPTTSPNQLSGRELLRIGEV
                     HDKQEHWPETLTYYQLALSKFREKKQQQGIATTLMKIARVHERQGKLQDAHASLREAE
                     QLFAQAADRSAHAEALLAMGRVAAQLGQRDESRDALTKAAALFTRVRNARGWNETMVQ
                     LGLLQVVEGSADAGLSSLQQAAEEAHTRRHVDQQFTATVALGDAHWLLGRLEEARTHY
                     LDALALAQAEHHLPFEGMLHLRLARLDQGKDTLNDRVALGKRAIQIAQAIHDTAAEAE
                     AWSLLADLHRQLGQQAEADTAEMRALALYRSRELFVHGVQ"
     gene            complement(28334..29572)
                     /locus_tag="PK063_11150"
     CDS             complement(28334..29572)
                     /locus_tag="PK063_11150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TCR/Tet family MFS transporter"
                     /protein_id="HMZ97655.1"
                     /translation="MAHFMNQAQPSVPPRQAAVFFILVTVVLDMLSFGIIIPVLPKLV
                     EEFLGGDTAQAAEIYGLMGTSWALMQFVCSPIQGALSDRFGRRPVVLLSNLGLGLDFI
                     LMAMAPSLAWLFGGRVISGIASSSFSTAGAYIADVTAPEKRAAAFGLMGASFGLGFVL
                     GPAVGGLLGALDPRWPFWGAAATSLLNACYGFFVLPESLPVEKRAPFRWQRANPAGAL
                     ILLRSHHELFGLATANFLMNLAHGVLPSVAVLYLGYRYGWGPSAVGFTLAAVGICAMI
                     VQGTLVRPITAKLGERRTLLTGLLCGATGFAIYGLAPTPLIYCLGIPVMAFWGLAGPS
                     AQVFMTRRVSASEQGQLQGAIASLTGIAGLIGPTLFTQTFALFIGPQADWHMPGAPYL
                     LSTMLLLVSAATAWRATRPV"
     gene            29671..30582
                     /locus_tag="PK063_11155"
     CDS             29671..30582
                     /locus_tag="PK063_11155"
                     /inference="COORDINATES: protein motif:HMM:NF015509.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HMZ97656.1"
                     /translation="MPATLQAFIAIFVLGALLRVSGLLGKIHAERLASFVFSISLPAT
                     ILVSLDHVTFTATAWRLPLAACLITVSMLLCAWQLARRLHLTRPTQGGLLLGTGCINS
                     VYFAYPVVLATFGDQGLARAILFDLGQTTLTLTLIYALAVGHGTKSTTARSAIVRFLS
                     SPPLWALCGSLLLSLFGLHLHDWLRQILTPLHLTTTPLASLVLGLSISVAVTHRTFAL
                     ATLGVVMRMAGGLLLGLGVAFVLNLTGIERAIVVLIAAMPSAVTAVIFAADTGLDEDL
                     VTSIVALSICVGIATLPWLPQLIRLLE"
     gene            30809..30937
                     /locus_tag="PK063_11160"
     CDS             30809..30937
                     /locus_tag="PK063_11160"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97657.1"
                     /translation="MHDAALWASWYVWLLAVPVLVIGTLIRDWLHRRHPVRLRKRS"
     gene            31323..31724
                     /locus_tag="PK063_11165"
     CDS             31323..31724
                     /locus_tag="PK063_11165"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97658.1"
                     /translation="MSSVSYRSLLAPAIPYVIVIPATILSGCVPPPPHQFVPGGPVGE
                     AGQTVPGPRQASDDEVRAMLAESSRHQSMPSERVDLNGLLTQISQATTFRQKQHLVDQ
                     YHHAALLLPEAERNQAFQRLRDLGNQGRMTP"
     gene            31779..32498
                     /locus_tag="PK063_11170"
     CDS             31779..32498
                     /locus_tag="PK063_11170"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97659.1"
                     /translation="MKPLRIITLLMLSLAVIMGVQCLTAEPAAAHNWLGDCVVDFDNT
                     FALTYIYGQARGNFGYPTGIDNTGELQPCNATHQACWTYRHRCFGNYINVEDMTYGHI
                     HLTFDSPSLLTPCFVDPGDGPGAGFGRTVGDNCVAADWIHEPRTLGTHGNDHWIKIWM
                     EDRVTHQPRVFDMPIIRVTGTEPIQFWFKKSNGSWWYWSNLAPNPWLVGGWVQDVVEV
                     RIRGAQAAKGPYFIGAFSILD"
     gene            complement(32629..>32891)
                     /locus_tag="PK063_11175"
     CDS             complement(32629..>32891)
                     /locus_tag="PK063_11175"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97660.1"
                     /translation="FSAVIPASALEGAQATAAMVIKADVLYWEEGELVVKEFSGHEER
                     LKVTPETKIEGVVAGRLKTGDKIVAQITDDRKALSIKVQIPE"
BASE COUNT         6818 a        10328 c         9104 g         6541 t
ORIGIN      
        1 gtggtgacct caagcctggc ccaaccgttc gagcgggcca cacgcttggc ctcgttcacc
       61 aacgcgcccc ccacgccttg tgaccgccgg tccggcgaga catacaactc cgggatgatg
      121 ccgaaccgtc cctccgcata gagggcacga cattcggcca gggcgataaa tcctgcagca
      181 cattctccat tccgcgccag caacaccgta taacttccat cctccagcca ggcgcgagcc
      241 cgtgcttcgg tctcagccaa cgaaaatccg aaggcggccg tcttgatcgc agccacaatt
      301 tccgccagca ggtctcccac caacttcgca atgatcggcg catcgaccgg ctgggctgcg
      361 gcaatatgga tcggcatgtc agattctacc ctttcccgcg cgacgctcac cgacgccctg
      421 atgcagcgca gcgacatcca gttcctgctc caagtgatgc aacacttcat cgctgatcgt
      481 gccgtcgtcc cgcagcccga tcagggcgac tcgctcggct gtgagcactt catggtgcaa
      541 acgctggacg gtttcaacac ttccctccgg acgctcctcc tcattcaacc cggtccgatt
      601 gagatgttcc agccggcgaa gatagcgcaa tcgcacccgt tcgatttgct ccctcggtac
      661 ccagtcctcg gtcatgacct catcgaggcg ggccagggct gcggtcgccg catgttcgcg
      721 cgccaggcgt tgctcccgat ccagatcatc ttcgtcttcg aggcgcagcc accggataat
      781 cggcggaagc gacagtccct gcagcaccaa tgtgacgagg atgaccgcaa agctgatcag
      841 gatgatctct gaacggaacg ggaacggcgc gccggtcccc gtcgtcatcg gaagtgccaa
      901 ggccgccgcc aacgtgacga tgcctcgcat gccggtccag gaaatgagaa acagcccctt
      961 ccacgacggc atcgggtcac gcgcgcgcag ggtcgcgctc aggcagcgcg ggatcagggc
     1021 cgccagcggc acccagagaa accgcacgac gatcgccgtc gcgctcacca tgagccccgc
     1081 gaatacgaca gggccgtact gccccgcagg gacggcatcc cggagggctc ccagctgcaa
     1141 tccgatcaaa ataaaaatca cgccattcag aacaaagatc aacagctccc acacggcgcg
     1201 agcctgcaac ctggtggccg gcgccactgc gccgctgaaa tactgccgaa gcgtgatccc
     1261 gccggccaca caggccaaca cggcagaggc atggaccgac tcggcaatga cccaggcgat
     1321 atagggaacg agcagtgtca cgccgatctg cgtatatccg tcctccgtga cacacagcgc
     1381 ccaacgggtg agccaggccg cggcaagacc aatcgccagt gccgccagcg cggcaaagag
     1441 aaaattgagc agcgttcccc cgagcaggaa tgagccgctc accaccgcac ccacggcagc
     1501 acggtacaac acaagcgcgg tggcgtcgtt gaccaggctt tctccttcca ggatggtgac
     1561 cacacgacgc gggatgcgca ggcgtttccc gatggcagtc gccgacaccg cgtccggcgg
     1621 cgagacgatg gctccgaggg cgatcgcttc cgcccatccg atgccgggca gcaacgcatg
     1681 cgccaccacc gcgacccccg cggtcgtcgc gagcaccagg ccaacggcta ggagggaaat
     1741 cggccggagg ttctgccgga actcccgcaa cgaagtgaaa taggcggccg cccagagaat
     1801 cggcggaaga aacaccagaa acacaaggtc cgggtgcagc gtcaccgttg gcaggcccgg
     1861 gaccacgccc agcaccagcc cacccagcac cagaaaaatc gggtacggga tgctgatctt
     1921 ctgcgcgatc gtggtgaggg ccagcaccac cgcgagcagc aggataatga tttccagttg
     1981 atgcaggctg tccatggatt cagaaccggc gatatgccgg cattcggcta catcccgacc
     2041 gtttcaagcc gctggaggtc ctctgtcgaa atggtgaact gatcggaccg gagatcctcg
     2101 gccatatgtt gctggtcggt cgtgccggtc aagggcagca tgcccatctg cattgcaaac
     2161 cggaacacca gttgcgccaa gcccatgccg tacttggcag ccatggtgcg cacatcggga
     2221 tcggagaaga tatcccggtt ggccgtgagc aacgagaacc cctgatagat gatcccgtgc
     2281 gcacggcaaa tctcccgtac gtctcggtcc cagcccaggg cggcgtaaca ccgattctgg
     2341 acgaccatgg gtttatgcgt cgcccgttca cagagcagcc ggagctgatc cgccgacacg
     2401 ttactgattc cgatcattcg cgtggttccc gccgcataga gactttcgat cgctccccac
     2461 acttcccaat cggcgtcact caacccccgg cgggcgtagg gcccatgtag cacgtaggag
     2521 tcgaggtagt cggtatgcag atgcgcgagc gaactgccga acgattgctt cacctgggtg
     2581 gtgagatcgg cctgcgcatc atagggcgtc cgatgatcct gtccgttgac cggcgtaaat
     2641 ttcgtctgga cgaacagccg ctcacgcggc gtgccctgct ttgccaacgc caacaaggcc
     2701 tctccgacca gggcttcctg gtagtggatg agctggttgg ccgtatcgat ggccgtgaag
     2761 cccgccgcca ccgcttgctg taccaattgt gtcgttgcgt cttttttcca cgccgttccg
     2821 tacatgaacg agggaacagg cacctgatta taggcagtca acatgaccag atcctccctg
     2881 ccgtacctta cacagatcct tgcggcggtc tcaatctttc acctggttgg gccaaggcac
     2941 cggacgacgc tggcgaccgt tctccacaac ctgctagagt gcgccgtcac cacgagagga
     3001 gcggaacaga catggaagca gcacaggcga atcaggtcgt ggaactgcga ctgacctacc
     3061 gatacatcaa agaccatccc tggaccgttc aagccatcaa cggatttctc tcggcctatt
     3121 tcatggaaaa gccgggattt tcggtccagc ggcattatga cgatctcgaa tcgggcatgc
     3181 acgtgtggat ctgcgacatt ccagccaaca tgaagatcac ggtgttgtta cggcggctgc
     3241 aggccgatat tcccccctgc cggcatcttc aacccgctgt cgagccgtcg gccaggccgc
     3301 agtatgtgat cgacagcccg gaataagggc gcctgcttgc gccgctccag gcctcctcgc
     3361 tacactgcgc gaaacatgaa cgacggagga ttaccatgcg agtgatcgtc atcggaggaa
     3421 caggcactat cggatcggcc gtcgtgaagc ggctctccac gcggcatgag gtggtggtgg
     3481 tcgggcacaa gaaaggcgcc tttcaggtgg acctggcctc gccggattcc atcaccagcc
     3541 tattcaaggc gatcggcacc tgtgatgccg tggtcagcac cgccgggatt gccaagtttg
     3601 cgagcctgga tgatctgacc tatgacgact acttcatcgg cctgaagaac aaactcatgg
     3661 gccaggcgaa tctggtacgc atcggccggc ccttcgtgac cgaccacggc tctttcacgc
     3721 ttaccagcgg agttctcagc cagaatccta tgaagggcag cgcctccatc agtatggtca
     3781 atgccggact ggaaggattt gtccgcgccg ccgccatcga tctgccgcgc ggcctgcgag
     3841 tgaacgtcgt cagcccgcct tgggtgacgg aaaccttaat cgccagaagt atggatcctt
     3901 ccatcggcat ccctgctgat caggtcgcgc aggcctatgt ggcaagcgtg gaaggcagca
     3961 tgacgggaca gacgctggat cccagacaga tcgccgcaac ctagtgcgac aacgcgccgg
     4021 tcaccctgcc gtgatgtgaa acacccctaa cggataggcg tggccgttca cgagcagctc
     4081 aatgcggtgt aagccgggat agtgggtgcg agtggtgagt tgcgtgaggg ccaacgattt
     4141 gctgaagcga agcgtctccc gcgccgccag ttcgacggtt ttgaatttga acaccttcgg
     4201 actgtgtttg ccattcgcct tgaggtagtg gacgcgcaaa tccagcagca cccgttgtcc
     4261 cccggaggct tgattcgcca cctcccaggt gacgcccact gacgatccga tccgaggccg
     4321 tgacggcgcg atgcggatcg tctccacggc gaccaacggt gtgtggccga agcccagcac
     4381 atggagcgct cctgcttctc cccgcttgac cgccgaccgg agagcatggc gaatgatcca
     4441 ccgccgctcg gccgttgcgt tctccagcca ccgcctggcc gtctcgacca gcacctcgga
     4501 atggtctttc ccgatgtcat tcagattgtt agccacactg cggcgcacgt agagtgacgg
     4561 atcgtctttc aaccgctcca acagggccag caccggccgc ggatcagcct ggaaggcgcg
     4621 cagtctcggt gcccagggca atcgcgggcg agtgccttcc gagaccaggc gtcgcacgtc
     4681 ttcactggga tcagccgtcc attccgcaag acgggccaac gtggcagcct ggtgtcgctc
     4741 gagataccgg cggatggaga actcggccgt gaatcgttgc gtcagtacat actgtgcgcg
     4801 catggaggct tcgaaatggt ccaatccata ttcagccacg aagaagacat gcggaagaaa
     4861 caaaaaggcg cccatgcctg aggcagtctt tcgcttcgac tgctgatcaa gcgacgccag
     4921 aagcatctca agagcccgtt catagtcatc cggcaaatgg cgtcgcaaga catgcgcgat
     4981 cttccaggcg cgcggcatca attccaactc gtcataacca tccagcaccg accggacgaa
     5041 tgccttctcg tcgaatcgag gcgatacggc ggcaatcatt cgcgcaatgg tccggggaac
     5101 atcggccccg aaactattct tcagcggttc cgccatgact gttcagccac cggcaaagac
     5161 cggccggaac cccgctttgg tcaaaatacg agcgatgtcg tcacgccggt ctccttgaat
     5221 ctcgatgcga ccttccttca ccgtccctcc aacgccacag gccttctgca tctccttcgc
     5281 cagctgttct ttctccgtct gactgatgcc gacaaatccc gtgaccaccg tgaccgtctt
     5341 gccgcctcga tgcgctgtct gcctgatgat atccacccgg ccgcgattct tcgccggagc
     5401 cggtgccggt gtcccgagct gcttggcctg ctctcgcggc ggggccgggg gcaagaccac
     5461 gtctttcaac gctgcaaacg ggctcttcca cgtcacgggt tctccatcgg taggaatgcg
     5521 cgtcttttct ttcatgccga acctcttcct cgttgactat tcacgcgccg gctctttcca
     5581 cagcaacagg tccatctgcg ccgcattcgt cccgtctcca atcaacacct gcccatcttg
     5641 aatggtgcaa tgcagatcca tactccgctg cgccagactc gtcagcgcac gactcccttc
     5701 caaagacaga ttcacgatgg cgagattgtt caaccggtca agcgcggcac cgtgctgctt
     5761 ccaccattgg tccgccgcac gcccaccata ggtatagacc cacacctgcc tggcgcgacc
     5821 gcaggcccgg cgaatcgtct tttcgtccgg cacacccact tctatccata actcgatcag
     5881 accggtcgca tccttctgcc acaacgccgg ctcatcctcg gtgctcaatc cacggccaaa
     5941 cgacagggct tcatgcgcgt gacgggcaaa cgcaagcagg cgaaccatca tgcgctcgtc
     6001 ggtttccgat ggatgccgcg ccaaagtgat gctgtggtct tcgtaatact ggcgatccac
     6061 gtcggcaata tggaggaccg ccttacaaat cgtcgcgttg ggggccatgc gattccttga
     6121 aaacagaggg aggagcccga tgaggcaggc ggccgttatt tcctcgcgat cttctcttca
     6181 gcaaaagtcc gttcaatcat gaagcgcaga tcgctggcaa ccgtggccgc gtcgataccg
     6241 ggactgatct cgatccagta gtggaggaca aacactaacg catgctcgct gaaatcttca
     6301 aacaatacat acggctccgg ctccttgaga atctgcccgt gctcaccggc cagctcacgc
     6361 agcttctcct tcacatgccg cgcatccgac ccggtcgcca ccgcgatgcg gagcgaatac
     6421 cgtttacgaa agctggaata ggtccagttc gtcagatttt tttcgagcag attgctgttg
     6481 ggaatcaagg tttccacgcc gttgatgtcc cggattgtcg aggagcgcag accgatggtg
     6541 gtgaccatgc ctctgattcc atccacctcg atgacatcgc cgacgcgcag cggccgttcc
     6601 atgagcagca gcagtccgct gatgacgttc ttcagcaaat tttgcgtacc gaatcccacc
     6661 ccgatggcca gggcgccgcc gagaaacgcg aaagcggtga tgggaatttt cactgacatg
     6721 agggtgacga tcacaaggag gaggaaaaag caggccaggg cccactgccg aatgatgttg
     6781 gcgacgttgg gatcgatctg cagcctggcg atggcctggc gctcggcaaa ccgggccatg
     6841 attcccgcca cccagtaccc gacgatcaaa atcgccagcg ccgtcacgac tttcccgacc
     6901 gtgacgctcc gtcgaccggt gatgttcttg ccgtccactt caatggtgtc ttcggcggca
     6961 aacaattcca catgccaggc attccccagc atcaccacgg aggctcgccc ccactccttc
     7021 atgcgcgcga acactgacct ggcctgctca cggtgggcaa attccgcctg tttgttgtcg
     7081 atcaacccca acaaggaatc cgtccgctgg agcgcgcgcc ggtacagatc ttcacggtgg
     7141 cgatagagcc ggagtttgtc cgtgaacact tgcgccctgg cggccgaagg agcctccgca
     7201 aggcggtctt ccacatcact gatgtgattg cccaccatgc tcagttgctg actgccgtat
     7261 tccttccagc ctcgaatctg tttggcggcg gcggcgatct tcgcattcgc ctcccgctct
     7321 tcgacgacgg agagcgtttc ctgggcagtc gcgaaacgga tgtcccaaat atgtcgttcc
     7381 tgctcaagac ccgtcagcat ctcgcgcagc aactccacgt gcagattggc gttgtcgaat
     7441 tgcagacgct tcagttcgac cgattcggtg agcgcggtca ggcgatcccc cttcggccgg
     7501 gaggcgttcc tcttggacga agagtctttg gcattcgccg cagcgagcgc agcttctccg
     7561 gccgcaaccg cctggcgttg cgtcgattgt tcgaggaccg ctcgctcgat ttcatccgtc
     7621 aacgattgat gttcggcatc cagccgcttt ttgattttgt cgtaatcctg ttgggtaaat
     7681 gccgaatcct gttcggcaac ggtgcgctgg cgggtcagca atgccatacg atgacgcgct
     7741 tccgccacct cttcctggat ctgcttcttt tccgcctcca acatgccggc tcgtgcgcct
     7801 tccactcgct cgcgcaatcg agccagatcg cggtctcctg tgagcgcctc ccgcttggca
     7861 ggatcctgga cctcttcgag acgctccgac aattgccggg ctttttcctg cgaggctttg
     7921 agactgcgct gcgtgctctc ggtcaggctt tcggtcatgt tgagtctggt ttgggcgcct
     7981 tgtgaggcga gggtcatcga tcgaaccgca tcgcgcagct catcgatttt caacaccgaa
     8041 tacggcgccg gcgtagaaaa tccatcccac tccttttcct ggcgttcagc ttcccgcacc
     8101 cgttgccgca tctgctcgag attgcgcaag gcatcgagat gttgctcata gatttgcacc
     8161 aactgctgca gcagcgagcg ccgctccgcc gtgcggccat ccacctggtt ccccgccgtt
     8221 cctttgcgct gagcttgtgg tgtggtgagc tcgctcagtt ccttttctgc cgctgcacgt
     8281 ttgtgttgga gatccgcggc ggcggcatct ggagcgggtc cattggccgc cggctggtcc
     8341 aacttgaccc cgaccgtttc caacgtggca cgaaccgcct tatcggtaga cgaggaggtc
     8401 gactgagctg agacagcaga gatctgcatc aacgagagca ggaagcagaa ggcaagcgtg
     8461 agggggattg gcacgaacgt gaacctccgc gatcgtaagc gagtcttctt catatctaca
     8521 gaggtgggcg ggattgatca agtcgcagga acgttgacag ggaggacgcg cgtccagctt
     8581 agcaaagccc tgtgggacaa gtcgtgtgtc gttcgactga tgtggcaccg acgaagaacg
     8641 gattccgtat gaacggctgc gccctcactc cagttccgca atatacattc cctcaacccg
     8701 ctctcgggcc cactgggtct tgcggagaaa cgtgagactc gatttgacgc tcgggttatt
     8761 caagaagcag cgcaccggca gacgacggcc aagttcagcc cacccatgcc gctcgacaag
     8821 cgtggtgacg atcttctcca gcgtaatgcc atgcaaagga tcgcggggat gattcaacat
     8881 gttactgcag ctgctttagt tcgcattcta aactagttca acttttgctc tggcaacgtc
     8941 cctcagaatc atgggtgcca tccaagctcc agcagacggc tcgatgccac ccatagccag
     9001 gggaaaacac ccatgattct gttcgatttc tgcaggttgc attttgcgca taggatccga
     9061 acgttttgcg ctgaaagact gcttccaccc ttcgaatagg gtatgtcgtg atcgtaatga
     9121 agattctcct gcaaaccaca ttgaacacat ttgccctgat ctcgtttcca aacttccact
     9181 ttcacatgcg tgggaatgag tcgtttgtgt gatagttccc ctattcgacc aaaggctttc
     9241 ttttgaacgg gcttgaggaa gaactggaac actcttcttt tttctagccg tgatataagg
     9301 tgcgcgtcaa acagctcaaa gaatcccttg tagcaccata ccccaacagc gattttctcg
     9361 tagactttga ctaactccgc cttttctctt agtccatgct tgaaatcagt ggcggctcga
     9421 aagaaccgcc cattttcggt caatgttccc tttggcgtgg tcattggttg atccaccgtc
     9481 ttggggttag gacaatcctt tgtgcgtggc tgatcatggc cttcataaat cagtattcct
     9541 gtggcatcat caactacatc tcgataagga gcgttggctc gttgagacat gagtagaatg
     9601 gaatagtcct ttcccactcc aaaattcatt cccttctgaa gcatcaattt ttcagcgctg
     9661 accaactcac cgtagcttat aatgtcatca acgttcatgc ggccctcatg gaatgctaga
     9721 catattcaga ctccacattc agaacgttat gcggcagtgg gagtatatgc caagtgaggt
     9781 gtatgtctcc atgagggcca atctctcaag ggacttacat cacccaacga ggggagtccg
     9841 cgaccgcgcg ttgcgcgagc atggggacca cacaggttgc ccggcccccc tctccccctt
     9901 cttgccgccg ccccgctcag actgataaaa gaaggcgttg caacccagcg acgccaggcg
     9961 gccacatacc ccctgttccg tcgattcccc taaccaccaa gagcacgtta tgtccctgcc
    10021 ggttgagaag tccgcctccg acgagttacg gcgagaagtg ctgcgtcggc gcacgttcgc
    10081 cattatttcc cacccggatg ccgggaaaac cacgttgacg gaaaaattac tgctctatgc
    10141 gggcgcggtt cacttggccg gtgcggtgca ggctcgctcc acccaacgcc aggccaaatc
    10201 cgactggatg gaattggaac aggcacgcgg catttcgatt acctcgacca tgctgcaatt
    10261 cgattatcaa ggggcgcggg tcaatctcct cgacacgccg ggccaccagg acttcagcga
    10321 agacacctat cgtaccctca tggccgtgga tagcgcggtc atggtgctgg acggcgccaa
    10381 gggtatcgag ccgcaaacca agaagctgtt tgccgtgtgt cgcaaacgcg ggatccccat
    10441 cctgaccttc atcaacaaga tggaccagcc gggccggcac cccttcgatc tgctcgatga
    10501 gatcgagcgc acgctgggca tgacggcggt cccgttcaat tggcccatcg gcgaaggatc
    10561 cggttttcaa ggcgtgtacg attttcagaa ccgccaggtc ctgttcttcc agcgcacctc
    10621 gcacaaccaa cgtcgcgccc cgatgacggt cgaggccttc ccgaatccga aactcgcgga
    10681 gacgctgggc gacgcctatg gcccgctgca ggaggaaatc gggctcttga cgggcgccgg
    10741 cacctcgttc gatcgagacc gcttcctggc cggcgaactg actccggtgt tcttcggcag
    10801 cgcgctcacc aacttcggcg tcggaccgtt tctcgacgcc ttcacgaaac ttgccccgcc
    10861 tcccggaccg cgacacagcg cccagggcct ggtgcagccg acggacgaga ccttttccgg
    10921 tttcgtattc aagatccagg cgaacatgga tccgcaacat cgcgaccgca tggccttcct
    10981 gcgcatctgc tcgggccgat tcgaaaagga catgatggtc catcacgccc ggctgggtcg
    11041 aaaaatccgc atgacgcgcc cgcatcgcct tttcggccgc gaccgcgaaa cgatcgatga
    11101 agcctacccc ggcgatgtag tgggactggt gaatccagga ctgtttacca tcggcgatac
    11161 gctgacctcc gatccttcac tgaccttcga tcccattccg cactttccgc cggaatgttt
    11221 cggcctgttg cggacgcagg atatctccaa gcacaagcag tttcagaagg gactcaagca
    11281 gctcgaagaa gaaggggtca tgcagatttt ttattcaccc gaccacgtgc gccgggaacc
    11341 ggtattggct gcggtgggtg agctgcagtt tgatgtggtg atgtcgcgac tggagaacga
    11401 atacggagtc aaaaccaccg tcgagcgtat gccgcatagt ctggcgcgct ggatcgtcgg
    11461 tgatgcggca accatttctg ctgtctattg gccctccgat accgtccgcc tcgtggatca
    11521 acaaggccgc gccgtcatgt tgtttaccac cgaacacctg ctggcctact gcatcaaatc
    11581 caacccctcc atcaagttcc tcttgcggga agaagtcgag caggcaaccg cacagtagac
    11641 gagccgttct cgcaaggaga cggggctccc acgcaacgtg ctgctgcgca gacgcatgag
    11701 aaaatgtgtt ataacaaact aaccgtccag gaaagccggt cggggcttcc tggtaggatg
    11761 actgcgagca cgatcacacc ttttgctgtc cttagcgcct caggctaact cggcctgggt
    11821 gacttgcccg cctcccgtca tcaattgaga cgctgccgtt cccatgccga gcctggaatg
    11881 ggtgcgttcg aatacgccgc cgaccccgag tggcaccgtc aagtgacgag acgacctatg
    11941 aaccggacaa tgatgcgagg agaaggacca tgcccaaggc aagaagcgca aaaaactgtt
    12001 actactgcga agcggaagat cgaattaaaa tgacatttat gctctgcggt ctctgccatc
    12061 ggcacttctg cagcgcccat ggcgtgcccg acctcgagca atgcacgaag tgcctggagg
    12121 cgagcgaaga aacggagtaa gccgcaaaaa tgccgaacca gtctgtcagc ggcgttctcg
    12181 catcactcgg gccctcaatg gacttctgag ttactcctca gccttacgct tgctgcggct
    12241 ttgttgaaca acccttttgc agcatcctgt attcaggact tcgatctcgc cctttgaagt
    12301 ggacggctca tcaggccgtc ttttgtttcc gcttcttctt ttcgatgccc accatcaccg
    12361 atacgcgagc ctgcttcgat agggcttggt cgatccggct tttgccgttg gtcgtcagaa
    12421 tcaccaggcc gttgtggtct tcgatgcgct gcagcagatg ggctgctccg gcattggcgt
    12481 aatggcttgc gccatccttg gctggccgat gtttgccgaa caaggcatcg gctccgtcaa
    12541 agaacaaaat cgacccgctg cgttcagcgt cgtcgaagac ccggttgata tttttctctg
    12601 tttccccaac tcgctggctt accacagagg agagattcac tttcgataag tccagctgca
    12661 attcttccgc gactaattcc gctgccttgt tcctgcgcag gggcgtggaa ccggacaaga
    12721 caacgactgc caccgaggat ttgttcgtcc gggtcacctt cgcgcggcgc gccggtgcct
    12781 gcttcctggg ggcagccttc ttcacgacct tcattccaac tttttttctc gatatcttcg
    12841 ctgccgcgct caccggccgc ttacccttct tccctgtcat ggtcctcttc ctctccaatg
    12901 attgcttcat accgttcttt gctcactcat cgcgcaggct atgcttacca tactttgatt
    12961 gctcagcgct ttttgtcgaa tccggaatcc cgccacttct ccagtagggc aatccgccgc
    13021 tctaattgag gaatggtcgc ctgatccacg cggccgccgg tccgcttgat taattccgcg
    13081 ttaagttgcc gatgatccat tccacacttt ctcgccacgg ctcccacgag aagccgatgt
    13141 ttatcccgca actggttctt ttggtcatgc agcgccactg ccggctccgg gtggcccttc
    13201 cctgcagggg atggctcgcc ttcatccgcg ccgatcaagg catcgagccg cgccacacca
    13261 ttgagcggaa tgtattcttt cagcgaggtc gctgccgtcc cgaacaacgt ccgctgcacc
    13321 gccggcatga tctcctcgag cacatggtcg cgctcaacct tgatccgctt ggcataatgc
    13381 accagcgtgg cgtctttggg caggtagagc caggcccgtt gcggtttcgg cactttgtcc
    13441 tgcatccgca caaagcgccc gacgacctgg cggaaataca tttccgtcaa cacgttggtc
    13501 gcatacaccc cgacccggag gcgcggaata tcgacgcctt cgctcaccat gttcaccgcc
    13561 accagccatt gctgcgtttt gtggtgggca aaggtttcga tcgttttcga ggcggaagga
    13621 tcgtcggaga cggcgaccag cgcacgcgtg cccgtgagtc gatgcaccag atcggccact
    13681 tgccgtgcat ggtcctgatt catggtcacg atcagaccgc ccgcatccgc ctgttcctgt
    13741 ttgcgcaggc gctgcaactc ggcatgcgca tcactcaaca ccggacccag ccaggtttcc
    13801 tggagcaagg cggttttgag ccgctcgcgc tggcgctcaa aggtcaatcc gtcttcgaac
    13861 gtggcccggt gttcccgccc gtcggataac caggtcagtt ctccctcgta actggggaac
    13921 agaatcggac ggcagacgcc gtcccgtatg gagtgcgaat acccataggt aaaatccgcc
    13981 tggctctcgc cttgctcata ccgcacatac ggaatgggat tgttatctga ccggaagggc
    14041 gtacccgaca gggccaggcg aaacacggct tcgccgaatg attcacgaag cgccttgccc
    14101 caatccttgc cgtccccggc atggtgcaac tcgtcgagaa tcaccagagt cttccggttt
    14161 cggcaggcgc gccgaaacac gtccggcgcc agacagacct gctgataggt cactaccgcg
    14221 ccatgataat cacgcgcctc gcaagcctgt tcattggaca aggccgggtc caattgaata
    14281 ccggcctgcc ctgctgccga cgcccactgt gttcgcagat gattcgtcgg acagactacc
    14341 agcacacggc tggcggcacg ctccgccaga taatgatggg cgatccgcaa cgcaaagcgc
    14401 gtttttcccg cagcgggcgt cgccgtcacg agataatctt cgcgcttttg cgccaacaca
    14461 tcggccaccg ctcgcgcctg ccagtcgcgc aacgcggctg tccacggacg aacgttcacc
    14521 cgcgcctcat ttcaccttga tcgctatact tacacatgaa tggtattcgc acttgtcccg
    14581 ccgccgccgt gacacattcc gtggcatcag cccgtgggca gattacgcgt gcatcctatg
    14641 ggaatagctg tcagacgtgc ggcgcatgac tcgagacagg ttgggcggaa aggggcatcg
    14701 cgatatgttc gagtgatcgc ccttcggcct tcacccctaa ccacaactcc acgatggcac
    14761 cgattaccat catcccggct cccagcagat atccatacat gacactctcg gctgatgttt
    14821 cgatcagctt gccgtacaac cacggggccg cgatgcccgc accctgggct accacgaaga
    14881 aaaaggctat ggccatcgcg cggatctcca tcggaaagat ctcgctgacg gtcagatagg
    14941 cggcactcgc cccggccgaa gcaaaaaaga aaatggccga ccacgcggca gtttgcgtga
    15001 cagaggtaaa ggctccctga aaaaacagat agccggtgga cgccagcaaa caaccggcaa
    15061 ctgcataggt gaggctgatc atttgcttgc ggccgatggt atcgaaaaag cggcccagca
    15121 acaaggggcc cagaaaattg ccgatcgcaa acggcacgat atacagacca atgctgtggc
    15181 tgggcacggc gtaaaatttt gtcagcacaa acggataggt gaatgaaatc gcattgtaca
    15241 tgaacgattg cgtcaccatg agcacaattc ccaacgaggt gcgacgggga taggccgtga
    15301 acagttcacg ggccacggta gccagggtgg caggtgtgcg tccgtgaatg gtaatcgagc
    15361 cttcggccgc cggaagcgcc ctcagttgtt catcgcgcat gatctgcgct tcaatgccgg
    15421 acacgatccg ctccgcttcc tgcacgctgc cgtgagtcat gagccatcgc ggactctccg
    15481 gcacgaccct tcgcacgagc aggatgctca cccccagtac ggctcctaag gcgaaacaga
    15541 gacgccagcc cagatattcc ggaatcagca gggggttcag gagcacaatg gtcaacagcg
    15601 cgccggccgc gctgcccagc caccagctgc cattgatgga cagatccgta tgtccgcgac
    15661 tgcgcgccgg aatgagttca tcgatggcgg aattgatcgc cgcatattcc ccgccgatcc
    15721 cggcacccgt caagaaacga aagaacataa agctccagag attccaggag aacgccgtca
    15781 tcacggtcgc agccaggtag agcatgaggg tgaacatgaa ccacttcttc cgtccctgcc
    15841 gatcagtcag gtaggagaag acaatcgcgc ccaccaccga tccggccaaa taggccgaag
    15901 cggtgaggcc gacttccgaa gccgtcaaat gcaacgtggt cgcatgcgtc aggaccgggc
    15961 caagcgcggc cacaatggac acttccagtc cgtccagaat ccaggtgacg cccagggccg
    16021 tcaccaccag ccaatgccag cgcgaccatg gcaggcggtc catacgttgc gggatgctcg
    16081 ttgtcacgga gctttctgag gcaggcatgc gtgatcgtac catgtgcagg taacacggac
    16141 gcctattgaa gtccctggcg ggcgaaaggt tgagaaggaa ggggcgacga gagcacaagc
    16201 cggccagggc cttcattggg gcaccccggc cggtttgaac atgtgggagt gtttcagtct
    16261 ctgaacaatc tgaccgcgac cttttgtccc ttgatgcgcg tccggcccaa ggcctcgata
    16321 atctgccggg ccgcttcttc ctgcacatcc accagggaaa atcgctcttc gacttcgatc
    16381 gccccgatca tcctcgacgg cacaccggct tcattggcaa tcgcgccgac cagatcgccc
    16441 ggtctgatgc ctgccgcccg ccccgcgccg acgtacacgc gcacggtgcc ggccgctcga
    16501 ccaccacgac tcggtccccc ccggggcgct cgcccgcgat ccccttgcgg agccgagcca
    16561 tacgctggac gtgatgaccg atagggctcc ggcgcgcgca tctggacggc gggaatttct
    16621 tcttcctccc ggtcgccccc gtgtgatcga tagaccaact tgatggcggc cgccgcaata
    16681 tccgccgggt cggccgatgc ggacaaggcg tccaccacac gccgaaaatc ttcgaggccg
    16741 cccgcttcca gggtttcttg aatcgacgac ttcgttcgct ccaaccgctt ggccagcaga
    16801 tctccgagcg acggcactgg cgcgatcgta atgcgcgcct tggtgtgctg ctcgacggcg
    16861 cgcaagagcc gctgctcgcg cggctcgaca atcgtcatgg ccgcaccttc ccggccggcc
    16921 cggcctgtgc ggccgatccg atgcacgtac acttccagcg atgaaggcaa gtcgtaattg
    16981 atcacgtgcg agacggacgg aatatccaat ccgcgagccg ccacgtcggt cgccaccagc
    17041 agttcggttt gccctgtgcg aaaggcctgc atgacacgat cccgctgaac ctggctcatc
    17101 ccgccatgaa tcgcttcaga tcggtacccc cggctattca acgccgccgt cacttcatcc
    17161 acctccagcc tggtgcgaca aaacaccaga gccgacttgg gcatggcaat gtccaagaca
    17221 cgggccagcg ccgacacctt gtgctggcgg gccaccacat acgccgtctg ttgcacacgc
    17281 ggagcagcgc cggctttcac cggctcccgc gcgatcgtga cttcgatcgg attcttcaga
    17341 tgccggcggg cgatggacgc aatccggggc ggcatggtcg ccgaaaacaa cgcggtctgt
    17401 ttcgtcgccg gcgtttcttc gagaatggcg tcgaggtcgt cggcgaaacc catgtcgagc
    17461 atctcgtccg cctcatccaa caccacgacc tgcagatcag ccagcttcaa ggtcttgcga
    17521 cggagatggt ccaatgcccg gccgggcgtc gccacaatga cttccactcc acgcctgagt
    17581 gcttgcagtt gcgggcccat cgcctggcca ccgtacaagg ccagcacgga gatccgcagc
    17641 tctttgccgt accgctgcac cgcttcgctg acctgcacgg ccagttctcg ggtcggcacc
    17701 aacaccagcg ccgtcggccg ctgccgtgga ccatgcgcaa tccgctgcag gagcggcaag
    17761 gcaaaggccg ccgtttttcc ggttccggtg gctgcctgtc caagcagatc acgcccttcc
    17821 agcaacgggg gaatcgcttc ccgttgaatc ggggtgggct cttcgtagcc caacgcttca
    17881 agggtagtca ggagcgaggc ttctaatccg agcgcggcaa atccagggga aaatcccttg
    17941 gcagccggct ctgtcggcga tggcgtcgtg gtgtgtttca tcaggagggg ctaaaccttt
    18001 cttcgtaaga ctagctattc atgctggcgg gccacataaa ttccaactcg ggaaacttgg
    18061 ctttgtaatc gtcgtggctg gcgtggatga ctttgatggc ttcgtcgcgg ccatacatgc
    18121 tcgtaatctc caccttgttg tgtgccgtgg agcccggtgc ctgcttatag gtcaggaaat
    18181 aatgctgcaa ccggtcaagg agggtcatgg gacattcttt gagatcggtc aacgttccat
    18241 aaacggcatc gtcccgcatc accgcgatga tcttgtcgtc tgcttcgccg ccgtccgcca
    18301 tgctgaatcc gccgatcggc cgggcggtca ataaaatatc actgtgggga atcgccttct
    18361 cggtgagtac gcagatgtcc agaggatcgc catcgccgat catgtccggc cggccggcgc
    18421 gggcaccgaa cagcttcgcc acttgctcac cgcaataggt ttgcggaatc agtccgtaat
    18481 acacggggca gaagtttgag aaccgctggg gacggtcgac tttgagaaag cccgtggcct
    18541 tatccacttc atacttcacc gtatcgctcg gtacgatttc gatataggcc gtcacgagat
    18601 ccggcgcctg gtcccccatg gacaccccat gccagggatg cgctttgaac atcaggctca
    18661 tcagtcgccg cgccgcatcg atttccttct tgctcatcct gcttcagtcc cccttgtgaa
    18721 caccttcgga attgacggtc tcacgatcgt acgatccggc aaggtctgga ttaattcgac
    18781 gacacacccg caatagagca ggagtatcag gctagagaaa cagtcagctt ataacacatt
    18841 gggggcgaag gaaacaggag ggtaaaaagt cgcgtctcgg cgcggacccg cggccgtcat
    18901 gaattctcgc ggtaatgtgc cgaaaacagc cgaaggggcc gggccgtcag gatcgaaagg
    18961 accatcactg accgcccggc acgtggttga gaggagtacc tgagaattaa aacgtatggc
    19021 ggacaccgaa gagcaggccc atcgaggacc catccccgtc ggcggaatta cgcttccagg
    19081 ccgtttccat attcagcatc aggcctttgg gcgcgccctg aaagaggctc gtcatgggat
    19141 agtccaagcc tgcgccaaat ctccaggcaa acgaatccgc ctgatctttg gtgttgatgt
    19201 tcacgccgat accgctggtg acatacggaa tcagggcgcc gaaatgtccc ggccgatact
    19261 cgagattgac cggcaacagg gtaatcgtat tgagcgatcc gttccggggc ccatcaatgc
    19321 tatggttttc ccattcgagc atcatcccga agcggaacca cttattgatc ccatacatac
    19381 cctgaaagtt gagcgccgga ccggtcgtgg agaggccgga actttgcgtc atgaaactgg
    19441 gacccacccg aaacccgaac gtcatcttgc cttcatcggc catcccctca tgcacccatt
    19501 cagccgcctg acaaatggcg ggagccacac tcaacaccag ggccaacagc aacaccttgc
    19561 ccgacactac gcagtgacga atcctcccca tacggtcctc ctgtgatgag attggacgga
    19621 tgtttcgact gcgcactcta ggcaagtggc ttccggattt tcaatatgcg ctgcgccgat
    19681 gacgagaaat aaaatggttc caatgattgt cgcaccttgc gacgacagac catcgtcgag
    19741 atgacgcaat agccccggga actacgtagc gccaagcagt gaaccggcgg gacctccggt
    19801 ccgacgcgcg agagtggaac catcgacaga tcgagaggag acgcgggccc cgtggaacga
    19861 gttatccatc aggcggcccg cgcaactaat ccgctgcggg ccgcctgagt ccagcctccg
    19921 aaagagcacg agtctcgaat gagacgagga accgtcgtat cgcttctcga ggatgcctta
    19981 aaacttggca ggaaactgcg cggccaaggc ctgcgtcagc gcatccgcca cgacataaat
    20041 atgctgcttc atgcctttcc aggtttccgc ctcacgcgca tactcgccgt ccttcagttg
    20101 ctgaaattgc gtgagatggt gggcggcatg ggccatgagc aatcccatca ccgtgtcctt
    20161 cggcaggttg gggttggccc cgctgaggaa ggtggcaatt tcagccgcat tggcggtcag
    20221 cgccttcacg gccgcatcct gctggctggt cgacccggcg acggtggcat ccaaatgttc
    20281 ccgaatcccc tggtaatgcc cggccaataa tgtaaagagt tgatccgccg ccggcttgcc
    20341 ataaaacggt tcgatcgacc gggcaatctg ctgggcgttc gccaccacat cggcttcagc
    20401 cgcgctccgc gctgcggcgt ttttatccat cgtcgcgacg gccacgttcc ggatagacag
    20461 gatatgcccc aaccagagat cacgaagcgc cgccttcgtt tccgccacct tagcctggtg
    20521 gcccgctgct gaagaagcca caggagccgg ggtatccgtc gtatgggcac aggccacggt
    20581 ggccacactg agcatcagca ctgaacaggc atgaatcacc ttacgcatgt cttctctcct
    20641 tgtaaaaata gtgaggcagc gccggacagc cgacattggc tgttgcactc gtgggcaagg
    20701 atagagaacg ggagcgaccc tgtaagttag cgcggtaaca ctggaggaga aatatgcggc
    20761 gctagaagcc ggaatcggcg aggctggcgg atgattgggc agtagacccc aggaatcggt
    20821 cgagttcggc ccgacgaagg agtaccccat ctttccgcgc gtaggtgatc agcccctgct
    20881 cacgcagttg gttcaggagg gtcgacacca cctcccgtcg tgcgccgatc atctgggcca
    20941 gatcgtcctg ccggaaatag tgagtcagac gaatccactc gccgtccggt tcgccgaatt
    21001 cgtcggctaa ccgtcccagc gtgcgcacca ggcgctccat cgtgctattg aaggacaaag
    21061 tctgaatctg atcatacgcc gctgacagct gttgggcgac attggaaaga aacaggagga
    21121 acgccggccg attgctttgc aaatgggcaa taaattcatc gaaactcagt tcgacgatct
    21181 cactgtcttc catcgcaatg gcctgttcgc ggcgctcgcc ggtgcaatga cacagttcgc
    21241 cgaacacttc accggtctgg tgcaggcgta agatcaattc acgcccgtcc tcggtgagag
    21301 aggtcaactt cacgaatccc cgacgaagat agaagacgct ctgcgccggg tcacccggcc
    21361 cgtagacgcg actgcccttc ggcatgtgcc gccccggtcg attcatcaat tgctcgcaga
    21421 gcttgccccg gaaacaaccg gacaaggcga ggcagtgccg gtggtccacc atattcatgg
    21481 ccgtatgaat catactaccc atcgagagac attgtagcgg ggtcgccacg cgtctgacca
    21541 gccccccaaa ggtcccatca cggtgtggcc atcggttcta gcactgcacc gtcgccttca
    21601 attatgatgg agattgttgg atttaaagac cacatcatcc ggacatcgac catgccggcg
    21661 ttcttgacag caacggctcg atcaggccgc cttggaattg ccagtgtcgg gggcctctgt
    21721 ctcgcgatct cactgaccgc cggtccactg ctttgggccg gctcctcgtc tccaaccaag
    21781 ccgggcaacg ggccgcaaga agcggaacaa ggccgggtac tcttcaatgg caagggcctc
    21841 tgctccacct gccatggtgt cgatggacac aagggccaac tgccgccgca cctcactcaa
    21901 cacatccggg acaatattgc acacctcgat cccgctcccg ccgatctgag gcaggccagg
    21961 acgctcaccc tcaccaccga caagcaacga ttcgagatca tccggcacgg gcatctgcgc
    22021 accgccatgt atccgatctc gaaggacacc atctccgatg aggagatact cgcgttgctg
    22081 ccctatctcg cgtccatccg cggtgcagta tcgcctcccg cttccgtgcc cgcgtcttcc
    22141 ttttccttaa gaggcgatgc gaacaacggg cggcagctct accacgaact cggcggctgc
    22201 gccatctgcc atggcatcga gggacacttg gattcacgcc ccccgatgtc ggctgatttg
    22261 atatcacgac tgaaggcgct tccccaccct ccggccgacc tgcgtcatcc gtccagcctg
    22321 accgctcaaa gtgacgaaga cctctatcga tccatcaaac tcggccatcc aggcacggcc
    22381 atgtatccga aaacgctcct gcgggacgaa gatatccggg acttgattgc ctatcttgct
    22441 gtccttcgtg gaggaagcca atagctgaag gaggaatgga gccagaggtg agtgcgatca
    22501 cgagggaagt gggaggggca cagtcgttcg gaagcggctc gcggaggcag cgaccacctt
    22561 tacgcacaac tcaccggcgg tcaccgcccc catgcccgga ataaccggta taggaccatt
    22621 agcttgggcc gggaggatct tcgtggtctt ctcccgtcag tgcttcggcc tcttccgctt
    22681 caagcccctg caggtcggtc aggatgcttt gcagcacctg acggcgctgc tgcagcccct
    22741 tcttcggcgt atcgcgtgtg agaggctcct gcgctgattc aggcaaattg acgatcgctt
    22801 cggcttcccc cagcgtcgcg tatttatagg actcgacgta gggatgagag ccgccgaata
    22861 ttctggtgag gatcgtttcg gtctcttcat cgaatgtgtc aaaggtggga tggacagcgg
    22921 tgacatgagc cagcccctca agcttatcga tttgtgcctt aatatcgtcg ttcctcattc
    22981 gaggttgata catggagtta acttcgacca tggcatgtct cctctcgtct gatggttttg
    23041 gtatatcgcc tccagaacgg aatgccacct aggaattccc cgagaatcga agttggaaca
    23101 cgcacaaacc aggcccgtca acgcaatgtc tcgtccgcca gcctgcgcac caggtatccc
    23161 acgatggcaa tattcaccgc cagcactgcc agccccgcca tggaccactc gcgaacgacg
    23221 gcgtgaaatt ccccgggcaa gaggacacac gtggacacga ccgtcagata ggcagcccag
    23281 gaggtttcgc tccagagacc gaacccctcg acaaacaaga gggccgcata gccgaggctg
    23341 acgagactca tcaacaacag actgtgccga ggcaacgaat ccaccgtgat ggcgagcgca
    23401 tgtagcagcc gtgtgtggat gttcaagtgc agggcgtcta gaacgggcga gagaccggaa
    23461 tcgatttcag gatcgatcca ccggagaaag cctgatcccg ccagcaggac caacaaccct
    23521 ttcaccagct tgaagagggc aatgggagcc aggctcgtct gctgcgatat cggcgcgctc
    23581 acaagcatag cgccactttc atccgcctga cgaggatcgg cccttgctca tcaggtagcc
    23641 gttcccctag gctagtcacc accaaaggct ctcaatgaaa ggttcacggt gatgaacgaa
    23701 cagtttgcac gaagcctggc cgaagcgtgg atcgacgcct ggaaccggca cgacctcgag
    23761 gctattctcc atcattatgc atcagatgtg gagtttacca gtccgtttgt gccggcgcta
    23821 tccggggacc cgtccggcac acttcacgga cgcgaccggt tgagcgccta tttccaaaag
    23881 ggacttcaca cctatcccga cctgcatttc gacttgttac aggttctgac aggcatcgac
    23941 agcctgttgc tctattaccg tagcgtcaag ggactgctgg caggtgaaat gatgaccgtg
    24001 aacgccgagg gattgatcca aaccgtgcgg gtccattacg tcaaagaata gaggccggga
    24061 gggaaccaga tgacggtgct cgcctcgtta gaccgccaag ccttgtctga tccggagaat
    24121 gatttcatct ggaggcagag cggcatcgac gaccagcgca tcggccggct cctccagaat
    24181 cgccagctgg ctatcaagca gttccggtcg catgaaatgg ttccggcgac cggcgagccg
    24241 ctcacgaaat acgtcggccg tgcctttcaa atagaccagt cgcagggcgt ggccgaaccc
    24301 ctcctcgact acagtccgat acctcgcctt caacacagaa caggccatca cagccggctg
    24361 gttcatccga acctgatcgg caatggccgc atgcagccgt tccagccaag ggcgtcgatc
    24421 ggcatcggtt aagggatgtc cactccgcat cttcccgatg ttggctatgg gatggagatc
    24481 gtcgccctcc aggaaccgcc agcctaagac ttctgcaagg cgacgaccga tcgtcgtttt
    24541 ccctgcccct gagacgccca tgaccaggat gattagaaga ggaggctggt cgatagttat
    24601 tgccggccca ctctctgaag agcctacttg cccaggagtg atgccggaag cacattcctc
    24661 ggtcgatgtg tcggccgcaa gatgcgcgat gatcaacgag gcgtcgctga tcggatcggt
    24721 ggtaaacggg gtgtcgtggc gcctggttac tgcggttgtg aggcgctccg ccgcctgtct
    24781 gacagcagaa ggaacggctt cgtgttgctg aatgcgacgc aaataggcca tcgcatccgc
    24841 ctgtgcaacc tgttcacttc gatgagcgaa ccaggattcg gcggcggcag cgaccgcccg
    24901 ccgtgcacag actnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    24961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnntcgatga
    25021 gcgaaccagg attcggcggc ggcagcgacc gcccgccgtg cacagactcg cgccttccct
    25081 tcattgcccg cactccaggc ctgcttcgca gtaaagagtt ccagcgcaat gcgagatggc
    25141 agcgacatgg gccgttacgc tacgtggctg aagttgaaac tgtcaatgag gccatctgat
    25201 gatgccacac acatctccac ccatcggctg atgcgaaggc ggagcctggc gttcagaacg
    25261 gaacatctgc tcgtcacagt gataattccc ccctctttca gggaaacccc tattcccctc
    25321 agaagaccgg gcaggcatac tcgctgcgca ctgacgagcg gacggcagca cgtgccacaa
    25381 agacctctgt cagggctgaa cacagcatga tgactcagcg tttgcgcaaa tccagcatgt
    25441 accgctttca cgattcggtg cgccatgatc ggaagtatct gatcgttgca ctggctgcag
    25501 cgctcattct cgccgccatc ctcgcaagcc tcggactgac ggtcttcccc accttcccca
    25561 aatagtcgcc tcttagagac gtttcggcta tgatcgcgtg agtccggcac acacctgtgc
    25621 gtcggaagcg catccatata ccaggcctcg ctgctcatga cgtggatcgt ctatattctg
    25681 gaatgtgctg acggcagcct gtatacaggc atcacaaacg atttggagcg tcgcatgcga
    25741 tcgcatgcaa gcggaaatgg ggcgaaatac acgagacacc gaggaccgtt tacggtgcgg
    25801 tataccgaat cactggctag caaaggcgcc gcgctgcaac gcgaggccgc catcaaggcg
    25861 ctggatcgag cggcgaaggt cgcgctgatc acggccctgc agtgctgaaa cgacagcgac
    25921 ctcgtacagc gtgtctgctt ggttcaggcc ttcggcctcg atggaaccgg caaacgcccc
    25981 tcatccatat caatcaaatc aaagagagta taacgggtga tatccaggct agttgcaaga
    26041 tctggaaggc tcatcatcag atatttagcc acacgagggt ccggatgaaa cgccgccgcc
    26101 ttctcagacc acgcctgttt ctctgcatct gaatgaacta tcgcctgttc atccacccat
    26161 gccaaaacaa gtgagtctga ttcagccgct agaatcgcac cttccagcgc gtccgcggca
    26221 agtccggtga atttcaagaa tctgccatca agagtaagtc ctggctttaa caaattccgc
    26281 acgtagtcca acggcaaagc acctgcggca tgaagccgaa ccttatcgat aagcctgggc
    26341 aggatcacat actcgccgag cttttgacga ggggatcgta tcggaaggtc catgcgcccg
    26401 agcgccccct tcttcaagct ttcaacagtt ctcaggaaac aattctggtt ggccgagttg
    26461 gaatgggcgc gccacccccc tcaccggtct ggcttatttc ttctttctca ccttcttggt
    26521 aggcgctggc gttgacttgg ctttcggctt cggcttgacg ccagcctgct tcttcgcggt
    26581 cccgcccaac acaatgaccg gcttttccgg agagaaggcg tcctcgatac ggctcttccc
    26641 gttggtcgcc agaatgacga gtccctggtg tgtctcgatg cactgcagga gatacgacac
    26701 ttcactgttc gcataccgat cgtgggagtc attgacctgc gtccgttttc cgaacaaggc
    26761 atcggcctcg tcaaagaaga gaatcgatcc gtggcgattg gccatatcga acacgcgtgt
    26821 catgtttttt tcggtctcgc gggcatactt gctcaccacg gccgacaaat cgaccgcggc
    26881 cagatgcaat tgcaactctt ccgccagaac ctcagccgcc ttttgccgac gaagcggagt
    26941 ggctccggac aggacgatca ccgcaccgga tggttggccg gcacgcgccc tggtggtctt
    27001 cttcacaggc ccggcctttt ttcgttgcgg agcctgtttc ttttgccggg ttcccgttgc
    27061 acctgccatg gttttcattc ctttccgcct ccaagtgagc ccttgccacg cttccgtcag
    27121 acaaacaggc gctgagtata accggttcct ggatttgtcg ctgaatttct tcatcgtcga
    27181 aagcataggg tcgatgcgcg gaaacatgag aaaaggaaca cgacctcagc ttactggctt
    27241 gaccttaccg ggacgtcaat gcaaagtacg cgacagatca cttcctcgta ggcccccact
    27301 ctgcagcttg atggagagac agcatgatcg ggttttggtt cctcttgctc tggtgcctgc
    27361 ctgcccaagc ctgggccgtt tcgccgggag acgtcacgcc taccacctcg ccgaaccaac
    27421 tctcaggccg tgaattgctt cgcatcggcg aggtccacga caaacaggaa cattggcccg
    27481 aaacgttgac ctattaccaa ctcgccttgt cgaagttccg ggagaagaag caacagcagg
    27541 gcattgcgac cacgctcatg aagattgcgc gcgtgcacga gcgacaaggc aaactgcaag
    27601 acgcccatgc gtccttgcgg gaagccgaac agttatttgc acaggctgct gatcgatccg
    27661 cccatgccga agccctgctg gcgatgggcc gcgtggctgc acaactgggg caacgtgatg
    27721 agtcacgcga cgccctgacg aaagccgccg ccctctttac ccgcgtgagg aatgcaagag
    27781 gatggaacga gacgatggtg cagttgggcc tgcttcaagt cgtcgaaggc tcggccgatg
    27841 ccgggctctc gtccttgcag caggcggcgg aggaggcgca cactcggcgc catgtcgatc
    27901 agcagttcac cgcgaccgtc gcgctcgggg acgcgcattg gctgctggga cgactggaag
    27961 aggcacgcac acactacctg gatgcactgg cgctggccca ggcggaacac catctgccgt
    28021 tcgaaggcat gctgcacctg cggctcgccc ggctcgatca agggaaagac acgctgaatg
    28081 accgcgtggc gctgggaaaa cgcgccattc aaatcgctca ggcgatacac gataccgccg
    28141 ccgaagcgga agcctggtcg ctcctcgcag accttcaccg gcaattaggc cagcaagcgg
    28201 aagcagatac agcagagatg cgggcactgg ctctctatcg cagccgggaa ctcttcgtgc
    28261 acggcgtgca gtagacgaag gcctgctcga ccacctgtcc aaacctgatc gctgtcagca
    28321 atacccaaat cgcttacacc ggcctggtcg cgcgccacgc agtagccgca ctcaccagca
    28381 gcagcatcgt cgacagaaga tacggcgcac cgggcatatg ccagtcggcc tgtgggccga
    28441 tgaacagagc aaacgtctgc gtgaacaatg tcgggccgat caatccggca atgccggtga
    28501 ggctggcaat cgccccctgc agttgcccct gctcggacgc gctcacccgg cgcgtcatga
    28561 acacctgcgc ggaagggccg gcaagtcccc aaaacgccat caccggaata cccaggcaat
    28621 agatcaacgg cgtgggcgca aggccgtaaa tggcaaagcc ggtcgcgccg cacaggagcc
    28681 ccgtgagcaa tgtgcggcgt tctcccagct tcgccgtgat ggggcgcacc aaggtgcctt
    28741 ggacgatcat ggcgcatatc ccgactgccg ccagcgtgaa gccgaccgcc gacggacccc
    28801 agccgtaccg gtaccccaaa tacaacacgg ccacgctggg cagtacgcca tgcgccagat
    28861 tcatgagaaa gttcgccgtt gccagaccga acagttcgtg atgggagcgc aagaggatca
    28921 acgcgccggc cggattcgcc cgctgccaac gaaacggcgc ccgcttctcc acgggaagcg
    28981 actccggcaa gacgaagaat ccgtaacagg cattgagcag actcgttgcc gcagctcccc
    29041 agaagggcca gcgtgggtcg agggcaccca gcagaccgcc gacggccggc cccagcacga
    29101 agcccaaccc gaaggatgcg cccatcaggc cgaacgcagc ggcccgcttc tccggcgcgg
    29161 tcacatcggc gatatacgcg ccggcagtac tgaaactcga tgacgcgatg ccggagatga
    29221 ctcgaccgcc gaacaaccat gccaggctgg gcgccattgc catgaggatg aaatcaaggc
    29281 cgaggccaag attggacagg aggacgacag gccgacgccc gaaccgatcc gataacgcgc
    29341 cctgaatcgg tgaacagaca aactgcatca gcgcccagga cgtgcccatg agaccataaa
    29401 tttccgccgc ctgcgccgtg tcgccgccca gaaactcttc gaccagcttc ggcagcacgg
    29461 gaatgatgat cccgaacgac aacatgtcga gcacgacggt gacgaggata aaaaagaccg
    29521 ccgcttgccg cggtggcact gatggctgcg cctggttcat gaagtgcgcc atcgtaccag
    29581 gctcgcgcct tcgccgcaca gaaaaaggcg ggatgcttca tgccgagcca tgcctcctct
    29641 tgccaacgat tttctgctag gctgccgccg atgcccgcca cgctccaagc cttcatcgcc
    29701 atttttgttc taggcgcgtt gctccgtgta tccggactgc tcggaaaaat acatgcggaa
    29761 cggctcgcct ccttcgtctt ctcaatcagt ctgcccgcta caattcttgt ctccctggat
    29821 catgtcacgt ttaccgcgac ggcctggaga ttgcccctcg cggcctgcct gatcaccgtc
    29881 tccatgctgc tctgtgcctg gcaacttgcc cgcaggctgc atctgacacg tccgacgcag
    29941 ggaggtttat tactcggcac cggctgcatc aattccgtct acttcgccta ccccgtcgtc
    30001 cttgccacat tcggcgacca aggattggcg cgcgccattc tgtttgacct tggccagact
    30061 accctgaccc tcacgctgat ttacgccctc gccgtcggac acggcaccaa gagcaccacg
    30121 gctcgctcgg caatcgtccg attcctgtca tcaccgccat tgtgggccct ctgcgggagc
    30181 ctcctgctat cactcttcgg gctgcatctt cacgattggc tccgccagat cctcacccct
    30241 cttcatctca cgacgacgcc tttggccagc ctcgtgctgg gactctcgat cagcgtcgcc
    30301 gtcacgcacc gcacctttgc cttggccacg ctcggcgtcg tcatgcgcat ggcgggcggg
    30361 ctgctgctcg gattgggtgt cgcctttgtc ctgaacctca ccgggatcga acgagccatc
    30421 gtcgtgctga ttgccgcgat gccctccgcc gtcaccgccg tgatctttgc ggcagataca
    30481 gggctggacg aagacctggt cacctccatc gtggcactct cgatttgcgt ggggatcgcg
    30541 acgcttccat ggctcccgca gctgatccgc ttgttggaat aagactctca gccatgccga
    30601 cagctgtggg aacggcatca cgccttgtga gctttttgcg acggcaaaaa ttgccggccg
    30661 catcgtgtaa cgaagcgcga caccgcgtta ctcatctatc tcgtgagatt tcctatagat
    30721 ttgcaggacg acggcacgac gcctcagaaa gacggtctac ggtatggtgc ttgctctctc
    30781 catcggcaca tagactggag gatacatcat gcatgacgcc gcgctctggg ccagttggta
    30841 tgtatggttg ctggcagttc ccgttctggt catcggcacg ctcattcgag actggttaca
    30901 ccggcgtcat ccggtgcgat tacgcaagcg atcgtagtaa agaaccatcg gcctcgatcc
    30961 tgccggtttg actcaggaca gtcagactcc ccacgcagca cgccacactc catcaacctc
    31021 atttcactct gataggcagc gaccatccgt tgcaagctac gtagtcgtat cggatgggat
    31081 acgacgttgt atcgtatgtg atacccgcgc ctgcacgccg cagcgcgact cctcgagctg
    31141 ccccagctca aagcacttgt tattacgtac gaagggtgcc ctctgacgtc gtggcccaaa
    31201 ggttgccttt cctgttttca gaaagagcat cttaaacatg cctggttgcc gtgcccgaaa
    31261 aataccgact ttgagccagg cagcttgcgg gacatacgca aggcagttaa gaggaggccg
    31321 tcatgagtag cgtgtcatat cgatcactcc tcgcacccgc catcccatat gtgatcgtca
    31381 tacccgcgac gatcctgtcc ggctgtgtcc ctccaccgcc tcatcaattc gtgcctggag
    31441 gcccggtcgg ggaagccgga caaacagtgc ccggtccgcg acaagccagc gatgacgaag
    31501 tgcgcgccat gctggcggaa tcttcacggc accaatcgat gccttccgag cgagtcgatc
    31561 tcaacggact actcacgcag atttctcaag ccaccacctt ccggcagaag cagcatttgg
    31621 tggatcagta ccaccatgca gcccttcttc tgccggaagc cgagcgtaat caagcctttc
    31681 agcggctacg agacctgggg aatcaaggca ggatgacacc gtgagggagc ggatacgccc
    31741 attcaacgac taagatccag ccaagaaagg acgtcaccat gaagccgcta cgaatcatca
    31801 cgctgctgat gctcagcctg gcagtcatca tgggcgtgca gtgcctcact gccgagccgg
    31861 ctgcagctca caactggctc ggagattgcg tcgtcgattt cgacaataca ttcgccttga
    31921 cctatatcta cggacaagcg aggggcaact tcggctatcc caccggcatc gacaatacag
    31981 gcgaattgca gccctgcaat gcgacccatc aggcctgctg gacctatcgt catcgctgct
    32041 tcggcaatta catcaacgtc gaggatatga cctatgggca tatccatctg accttcgata
    32101 gcccgagcct gctcacgcct tgtttcgtcg atcctgggga tggccccggc gcgggatttg
    32161 gacggacagt cggtgacaat tgcgtggccg ccgattggat ccatgaaccg cgaacactcg
    32221 gcacgcacgg caacgatcat tggatcaaaa tctggatgga agaccgggtc actcaccagc
    32281 cacgcgtctt cgacatgccg atcatccgag tgaccggcac cgagccgatt cagttctggt
    32341 tcaaaaaatc aaacggcagc tggtggtact ggtcgaacct ggcacccaat ccctggctcg
    32401 tcggcggatg ggtgcaggat gtggtcgaag tgcggatcag gggggcgcag gccgcgaaag
    32461 ggccatactt catcggcgcg ttctcgatcc tggattaacg gctgttgata cagcccagcg
    32521 gcagcgttcc ggcttcgctg agaggctcac catgcggtat atacacgatc ggccactttt
    32581 ctcgccgcgg ccacgctgga cggtctgttg aagggaacgg ctcgaccgtc attcaggaat
    32641 ttgcaccttg atgctgagcg ccttgcgatc gtcggtgatc tgggccacga tcttgtcgcc
    32701 ggtttttaat cgtccggcca ccacgccctc aattttcgtc tcaggcgtca ctttcagacg
    32761 ttcttcgtga ccggagaatt ctttgacgac gagttcgccc tcttcccaat aaagaacatc
    32821 ggccttgatc accatggcgg cagtggcctg ggccccctct aacgctgatg caggaatgac
    32881 tgcggaaaag a
//
LOCUS       DAOQPD010000043        30998 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_654_length_30998_cov_23.352648, whole genome shotgun sequence.
ACCESSION   DAOQPD010000043 DAOQPD010000000
VERSION     DAOQPD010000043.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 30998)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 30998)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30998
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_654_length_30998_cov_23.352648"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..222
                     /locus_tag="PK063_11180"
     CDS             <1..222
                     /locus_tag="PK063_11180"
                     /inference="COORDINATES: protein motif:HMM:NF020534.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0098609 - cell-cell adhesion [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta/gamma crystallin domain-containing protein"
                     /protein_id="HMZ97661.1"
                     /translation="GPKEYATLKNLAGKDWSNDIESVIVGSNATVRAYEDKDFKGTEI
                     AFAPGQRVPNLGKLDMANDIESLKITCGK"
     gene            complement(250..1164)
                     /locus_tag="PK063_11185"
     CDS             complement(250..1164)
                     /locus_tag="PK063_11185"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97662.1"
                     /translation="MNRRWIVALAFALCTIPSLVFAESPPQSVHWGAIAFPDHDPTLT
                     LSTAVLDRFTQFDGAGRRYNDINQTMGFNFFTISWTKPLTQLPGWNLNLTAGGGPTRD
                     GPSRFLQNDVVHKLRGFDPVPVGEKRDANDFMLSGTMTRWFGLLGTSEVFFAGVGGAG
                     GSLYYEPYVQAGFRRLAILNLIPVLGDYLRVSGLARYGRPFSGAAFHQVAPQSYLAQA
                     SVGLGNYHHWKDCTPWEIELAVTVDSGLFVDHRGDALEERFVSLALRYSAFTFETWND
                     LINQKDYGPTFGARLTLDLFYMYDRWFH"
     gene            complement(1264..>2083)
                     /locus_tag="PK063_11190"
     CDS             complement(1264..>2083)
                     /locus_tag="PK063_11190"
                     /inference="COORDINATES: protein motif:HMM:NF013740.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HMZ97663.1"
                     /translation="SRLAEPAAEWSTKVPVALRTVEYKIQPVKKSMQDVTKATELLSK
                     ATALDETKKVQQVEVKGDAWPIKVFSLTGELMMGFATTVMLLYFLLSSGDLFLQKLVK
                     VLPRLSDKKQAVEIVRNMEEQLFLYLFTVTGINLALGTAVGIAMYLLGMPNPILWGVM
                     AGLLTFIPYIGHIFGIVVVMLVAALTFDDLGQMFLIGGVYWGLAILEGSFASPMILGR
                     RLESNPVVLVLAIMIWGWIWGVGGALLAVPLLAAFKIMCDHLEPLQPIGEFLGK"
     assembly_gap    2084..2183
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<2184..4030)
                     /locus_tag="PK063_11195"
     CDS             complement(<2184..4030)
                     /locus_tag="PK063_11195"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012745.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HMZ97664.1"
                     /translation="MRERDKDAIAIIPAYNEAGTIHHVASRTLHYVERVVVVDDGSTD
                     QTVSSLRELPVTVLRHANNLGKAAALRRGMQHAVAQGATAIITLDGDGQHDPAAIPAL
                     LAMHRRDPRAIVVAARRRHRHTIPRLRVLAQRIADFWISLAAGCTIEDSQSGFRLYPI
                     SAWTAAGWPCDAASGFVFESEILIEAGRSGIPIRSVPISAIYGRHLRQSHFQSGRDIA
                     AITRMVTDKILSDWLRAPGTTVRRRRALGPAVPSPDGAGTPQVLASAQKPRILFLAEA
                     VTLAHVARAVALARSLDPDQYEVHLACDRRYHHLFESVPATMHPIRTISGAQFQDRLR
                     RGDPLYSKEELHRYVEDDLCLFAHVRPDAVVGDFRLSLSVSARVAAVPYLTVTNAHWS
                     PFAHQHFVVPELAITERFGPRLGQALFTMMRPFVFAQQGHALNQVRRDYGLPALPYSL
                     PHQFTDADVTLYADVPELVPTYHRPPHHHYLGPVLWSPDSVPRWWDSLPDTGRMAYVT
                     LGTSGRADLLPLILDALEQLGIEALVSTAGRSIPGRLPPGTRVAQYLPGQAAAARADL
                     VICNGGSATVYQALAAGKPVLGIPNNLDQYLMMDYVRRSGAGDYLRAGT"
     gene            complement(4027..4749)
                     /gene="fabG"
                     /locus_tag="PK063_11200"
     CDS             complement(4027..4749)
                     /gene="fabG"
                     /locus_tag="PK063_11200"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: protein motif:HMM:NF024950.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="HMZ97665.1"
                     /translation="MSKRALVTGGSGGIGQAVCQVLGEAGFEVIVHGCTRMDRAEAVA
                     QAIRDKGGKAEALCFDVTDAAQTRQALDRLQPAGPIQVLVNNAGIYDDAPMAGMTNDQ
                     WHRVLDVSLNGFFHVTQPLLLPMIRTRWGRIVTITSVSGLIGNRGQVNYAAAKAGLHG
                     ATKALALELASRHITVNAVAPGIISTPASLDTFGAEAIERLVPMKRAGTVEEVAGLVS
                     FLVSDTAAYVSGQIISINGAQA"
     gene            complement(4746..5222)
                     /locus_tag="PK063_11205"
     CDS             complement(4746..5222)
                     /locus_tag="PK063_11205"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97666.1"
                     /translation="MERRCDDIAELVPHRGTMCLLDSVETWDEHHIVCRATSHLRPDN
                     PLRDGSGLRTLCAIEYGAQAIAAHATLLGSGHRQRAAEGVLASLRHVTTTLSHLDGLK
                     GALTIVAMLQLSHQQGRIYDVTVTADGQTLLTGRLSVMLEADHSGEARSVSQEGAA"
     gene            complement(5222..>5997)
                     /locus_tag="PK063_11210"
     CDS             complement(5222..>5997)
                     /locus_tag="PK063_11210"
                     /inference="COORDINATES: protein motif:HMM:NF025100.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="beta-ketoacyl synthase chain length factor"
                     /protein_id="HMZ97667.1"
                     /translation="IGIAGPGLDGWAAARPILAGETEYRPAPLTPPNLKLLSAAERRR
                     CSQSARLAIAAAQDALLAGPLQGEAIATVFTSSDGDGAITQEICESLAGAAREVSPTS
                     FHNSVYNAPAGYWSIATRSQLSSTSVCAYDVSFAAGLLEAATYTTVERCPVMLVASDL
                     PFPRPLYGIRPVEESFAAALLMTPTSHPDACMRCEIALAPHQAITAFPATIPESLRSN
                     PAARSLPLLALLARQAADTVRLEYTDESDLVIDCKPEGH"
     assembly_gap    5998..6097
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<6098..7068)
                     /locus_tag="PK063_11215"
     CDS             complement(<6098..7068)
                     /locus_tag="PK063_11215"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: protein motif:HMM:NF006618.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase"
                     /protein_id="HMZ97668.1"
                     /translation="MMAPLTVTAMATANPLGLGLAETWQALRTERQGLRPNDFEDADI
                     KTWIGRIEGLETEPITGELADFDCRNNRLALVGLRQDGFEQAVASARQRYGPDRIGVL
                     IGTTTSGILETEWAYRRRAAGGELLPLTVRYRHTQNLFSVSDVVRRHLKLTGPVASIS
                     TACSSSAKVFASASRWMAAGLCDAVVVGGVDSLCFMTLYGFASLGLLSPRPCRPCDEH
                     RDGLSIGEAAGFLLLERETTRDSGLRFLGYGESSDAHHMSTPHPEGLGAVLAMERALD
                     RAELKPIDIDYINLHGTGTPANDLAEDRAIWKTFGERTPCSSTKERTG"
     gene            complement(7065..9386)
                     /locus_tag="PK063_11220"
     CDS             complement(7065..9386)
                     /locus_tag="PK063_11220"
                     /inference="COORDINATES: protein motif:HMM:NF015155.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MMPL family transporter"
                     /protein_id="HMZ97669.1"
                     /translation="MTLHARPALFLWMLLVFISGGIVANMTMTTDLTALLPRSADHRQ
                     ELLVSQLRDGVAARLILIGLSGAEGEALAQASRTIARKLRDTGLFASVNNGDPADFTI
                     VREVLMRHRYLLSAAVIPEHFTATALREALERQLQFLASPAGALMKTALPSDPTGEVP
                     HILAAFTPGEGPSMHQGVWFSRDGTRALLVAETSAPGFALDQQESAVQAVRTAFTSAG
                     LPEHAHLVMTGPGVFAVESRATIQRDSWRLSVIAITVVTILLFLVYRSVTPLLLSLLP
                     VLTGLLVGVAAVQTWFGFVHGITLGFGATLIGEAVDYPAYVFTQGIAGERLQQTLSRI
                     WPTLKLAVLTTVFGALSLLFSSITGLAQLGVLAFVGVLVAGFVTRWILPALPPGVIRS
                     APHQLLPMSWLPALASVNRIRWTIWVAALLALATLAMRHENIWDNDLANLSPIASPSK
                     TLDEQLRKDLGAPDVRYVLIVEGSSKEEVLQRSESAELPLRRLVDDGLLAGFDLPSLY
                     LPSDASQRKRQAALPSSDVLAASLAEAVKGLPFRAGLFEPFLHDVEMARTSPLIDIVN
                     LQQTPFFLKIRSLLVHTDDAWAGLVPLRHVTSPSGLADRLAREAGPGLTFLDLKSEAG
                     RLVNGYRHESLRLTALGVVAMTILLWWGLRDMALVSRVLLPPLLAILFVVTLLTVIGE
                     RLSLFHLVSLLLVLGIGLNYALFFNRPFSDEEEKRRTWLSLTVCMAATLSAFGALAFS
                     RTPVLHAIGLTVGLGAAGSLLIAAILGQQRVSQ"
     gene            complement(9383..9982)
                     /locus_tag="PK063_11225"
     CDS             complement(9383..9982)
                     /locus_tag="PK063_11225"
                     /inference="COORDINATES: protein motif:HMM:NF039988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer-membrane lipoprotein carrier protein LolA"
                     /protein_id="HMZ97670.1"
                     /translation="MKVPITLSPLILLCSLWAWLPASAEPAMGAEPFDVPGLMELLAK
                     VSSRQDRFTETKTIAMLTQPVVLKGTLAYVRPDRVEKHITSPYTEDLTVQGDRLTLSS
                     PKGTKQIAVDSHPLIRSFIEAIRASLAGELAVLRRLYHIKFQGTRQQWELTLRPLDAQ
                     AAEYVASIILRGEGDRLTTVDIRETGGDRSLMEIDGPVS"
     gene            complement(9939..>10600)
                     /locus_tag="PK063_11230"
     CDS             complement(9939..>10600)
                     /locus_tag="PK063_11230"
                     /inference="COORDINATES: protein motif:HMM:NF015251.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97671.1"
                     /translation="VYLLSGRHRYFDIHTEGASALHAVLAQNRGCILLGSHLGSFEVL
                     RAQGIFDHKLPITVIMHEAAASNLNEVLHNLRPEIRDRIIPPGTADTMLAVKERLDRG
                     EIVGILGDRLFNDEKGMACEFLGKTRMFPEGPFLLAALLQVPIVLFFGLYQGGRRYHL
                     YFEPLADTIPVNGARRSETLRPWIERYVSRLEHYCRVSPYNWFNFYEGPDHAQPSHPA
                     V"
     assembly_gap    10601..10700
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(10763..11083)
                     /locus_tag="PK063_11235"
     CDS             complement(10763..11083)
                     /locus_tag="PK063_11235"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97672.1"
                     /translation="MRTEKPRQIRRDHPALAGHFPGNPLVPGVVLLTELLSILEQEAG
                     MKPGPLELSSVKFLRLLRPEEPFTLRWRFLPNQDIAFAVTRGEDMIATGTVHRARVTT
                     QVAS"
     gene            complement(11087..12508)
                     /locus_tag="PK063_11240"
     CDS             complement(11087..12508)
                     /locus_tag="PK063_11240"
                     /inference="COORDINATES: protein motif:HMM:NF012711.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HMZ97673.1"
                     /translation="MMMQSIDSQMAPASPARRMHQPRAAAGYPLVGHHSVTSPLAWRR
                     DRAHSVHEFLCAAISLAAQLPRKHFAINLCRDRYHFAVGFAAALIARQISLLPTCRAA
                     EPLQQLARQYPGAYVLTDHDEGDIPIPRFSLLREMEQGVGPKDVPVIPADQIAAIAFT
                     SGSSGFPQAHAKSWGSLVMGARALGQQFGLTQSSSRVAVGTVPAQHMYGLETTIMLPL
                     QWGWSVHAGTSILPADLRTDLEQLESPAWLMTTPFHLKAFLRERTNLRGLEGIISATM
                     PLDRAIALSAERLWHVPVHEIYGCTEGGMLASRRTTAGEAWTLCHDLRMRHAEDTTWV
                     MGGHVGAWLQLSDRITLRSQREFLLLGPHRDLVKVAGKRASLTALNAILNRIPGVVDG
                     TFYWPDPGQTGTGRLRAFVVAPGMTRAAILAELRKRIDPVFLPRPLYVVDQLPRNTTG
                     KLPHEHLKTFARHIMHPQQHVHE"
     gene            complement(12505..12786)
                     /locus_tag="PK063_11245"
     CDS             complement(12505..12786)
                     /locus_tag="PK063_11245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004633317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantetheine-binding protein"
                     /protein_id="HMZ97674.1"
                     /translation="MAFSSQSQVGADGALEQELATLIVEALRLEVLPETIDPSSALFG
                     EGLGLDSIDMLEIALLVSKRYGVELRSENKAALASLRALANHIAQHRIR"
     gene            complement(12788..13609)
                     /locus_tag="PK063_11250"
     CDS             complement(12788..13609)
                     /locus_tag="PK063_11250"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013672.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HMZ97675.1"
                     /translation="MNTVSMRHSATNEGLGGRRPADAPLTLRFLVTFDDGPHPNTGKV
                     LRHLARNPVQPHIKGIFFVQTRHPKRGGSSDGRAMLAIEQAEGHLLGLHTGTTKGHLS
                     HTRMSPAELERSLLNGKEDLDQITGKPTMLVRPPYWLFNASTFDCYGRHRLHMLLSDV
                     KAFDGVNWGIHLLRRLNFRSQLAGLHARFLRGTLPVVNHTIPIVVTFHDTNSFTAEHL
                     GDYLSLLVEEAARLGLPLHSKPFIDDPDELLAAALRCAKTSTGTERNPALIQEAQ"
     gene            complement(13628..13900)
                     /locus_tag="PK063_11255"
     CDS             complement(13628..13900)
                     /locus_tag="PK063_11255"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97676.1"
                     /translation="MSRGWALGIAVLLTGCGPHYTIPNYDTNEIEKVISSGRSPQGCI
                     ENLKEDAKNLNVDVRLTDVQQQPSSGPISWIYTNTYMCTGKVVAKR"
     gene            14124..>14880
                     /locus_tag="PK063_11260"
     CDS             14124..>14880
                     /locus_tag="PK063_11260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HMZ97677.1"
                     /translation="MPAKKGSTARPSAAANQGQPTEEFEKLGVFYLGRPYALVTKQSR
                     PGWLLYDSKDLVTHAVCVGMTGSGKTGLCVGLLEEAAIDGIPAIVIDPKGDLSNLLLT
                     FPQLRGEDFAPWINEDDARKKGLSPADYATQQAALWQKGLGEWGQSGERIQKLRDAAD
                     VVIYTPGSNAGLPVSILKSFAAPSPEFLDDAELLRERISTTVTSVLGLIGLQADPIKS
                     REHILLSSILDSAWRAGRDLDLAALIHQIQTPPM"
     assembly_gap    14881..14980
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <14981..16792
                     /locus_tag="PK063_11265"
     CDS             <14981..16792
                     /locus_tag="PK063_11265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ97678.1"
                     /translation="GRDLDLAALIHQIQTPPMTKVGVLDVESFFPSKERFALAMQLNN
                     LLAAPGFAAWMEGEALDVGQILYGPSGKPRIAIFSIAHLNDAERMFFVSLLLNQTLGW
                     VRSQSGTTSLRAILYMDEIFGYFPPVANPPSKAPLLTLLKQARAFGLGVVLATQNPVD
                     LDYKGLANTGTWFIGRLQTERDKARVIEGLEGAAASSGKKFDRQQMEQILAGLGNRVF
                     LLNNVHEDAPEVFQTRWTLSYLRGPLTRTQIKQLMDPVKRQLPARTSRQDELGAAGAS
                     GSTSAASRTTASRPMLPPDVPQYFLPLRGTQPSGATLIYQPMVLGAAQVRFTDNKAGI
                     EATNDVTRLAAISSGVVPVEWEQSTAADVQVADLEREPAAAAEFAALPGAASKGKQYD
                     SWKSDLSGWLFRTQKLELWRSPTTNTLSKPGESERDFRVRLQQVGREERDRLSDELRK
                     KYAPKITTLRDRVRRAEQAREKQQNESRSSQVQAVISVGASILGAFLGRKTLSATNIG
                     RATTAIRSAGRVMKESQEVGHAEENVATLQQQLTDLEAQFKSESDALMAATDPLTEKF
                     EQISLKPTKSNIVVKLVGLAWVPAWRGADGTSAPAWL"
     gene            16942..22902
                     /locus_tag="PK063_11270"
     CDS             16942..22902
                     /locus_tag="PK063_11270"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ97679.1"
                     /translation="MGTHTLPPDETARVGALCRYRVLDSPPEADFDEMVQLAASIYKA
                     PIAAITFIDHDRQWVKAAVGLDTSQTDRPSGLCSFTIQGKDPMVIEDASADDRFSSHA
                     LVRGHPHVRFYCGAPLVTRDGYAVGTIAVMDSIPRTVKEDDLLTIRRLARQTAALLEL
                     RMLRSERSSVDSLSTDDQVETLTEAAFVIDRSGRILRANRGAERLLGVLASDLRGRLL
                     HECVHRPGDGDEEGQDGSCTLMHACLSGTAVLEQDDVFVNGDGSLLQVRWNHVPCWSG
                     GDWSGGIVAVRDLTIQKRNEEVLRLMAPTTRLTGTAFLQDLVETLVKTIGADYGFCLR
                     ALPEGRCAHSVAGWGPNGRLDPVDYALAGTPCEHVLHEGFCHYSSGVQALFPQDEVLV
                     HLSIESYMALTLPSPTGGPVGWIALLGRSPLKDAERAEALLRVAAGRAGSELGRHLAE
                     EQLKESEERYALALRGTSDGIWDWNVLAGQAVLSPRWKALLGFAEDELPDHESSFFQR
                     VHPEDVPRVKAEIERHFARRTPYDVQCRLLHKDGTYRWVQTRAQALWDDQGRAYRMVG
                     ASTDITERKQAEDVARRWQQVFDQAQLGLAHADLATNTFLAVNPAFARQCGYTVEELI
                     GRSIFFIYPPEEHAALEERIQRIHDTGGLTFESIHRRKDGSLFPVMVEVMLIRDADGV
                     PVSRVAYVKDITEAKQAEQARRASEERFRAAYRNATVGMSIADVGGRIQEVNQALCKI
                     LGYSEQELLANTFQSITHPDDLGQNLDRIQTLLSGRRVYDVFEKRYVRKDGGVVWAQV
                     GVSVIRDEEGTPLYTLAMVQDITERKHAQEALQLAKYTVDSATEAIYWVGADAELLDV
                     NDSACSMLGYSKDEFRRMRVHDINPNFQAETWPTFWAHTKERGRVSFESCHRAKDGRL
                     IPIDVNVNFVHYNGVECHFAFVRDITERKSAERALRASEERFHFAIEATNDGMWDWDM
                     RTDEVYYSPQWIRLLGYQSEEVLPTRAFFMTLLHPDDVARMMDVLQAHVDGRIPLKEI
                     EVRLRQKSGEFRWYLNRGKVVARAEDGRPLRMVGTITDISERKQSERERDEALSHLET
                     IMETVPDIIFALDLEGRVAKWNRKLETVTGYTREELQGKSALEMVPSDEAEKTAAAIR
                     EAYEKGYAELEGHLLAKDGRTMLYHWTGAPYRDLQGRVIGVTGVGRDITERKKVEQML
                     ASETRILEMMGSDAPLSAVLAEICLMIEGLSSGVLCSVLLLEEDEAHLRHGAGPSLPA
                     SYARILDGMAIGPARGSCGTAAFTGQQVVVTDIASHPFWADFRELALAHGLRACWSTP
                     IISAAGKILGTFAIYNQTPRQPTAEAPIVARASHLACLAIERKRTESALRLMQFSIQQ
                     AVDAVFLVSAEARILDVNEAACAMLGYTREELLSKTVHDIDTNFTRENWRARWQHLKV
                     RKSFSYESRHQKKDGTVIQTDTTINFLVHEGREYYCAFMRDITNRKRAEAQLHLTQFA
                     MERAADMVFWVDEAARLLLVNAAACERTGYTKDELLHMAVPDIDPNYQMEAWVRHWQE
                     LRETGRQRLETQHRSKSGEIYPVEVVANFVVFEGREYNFATVRDMSERQRTELRLRSS
                     EERFRLVAQATNDVLWDWDLVTNAHWWSPNAREKFGYDPQREPSIDAWTVRLHPDDKA
                     PILAMVQQAIESEVQTLAAEYRFLLADGTYGYFLDRAHIVRNEVGMAIRMIGAMIDVT
                     GPKRAYASLEEAYRRFQAMSQELQMVESNERRRLSRELHDELGQLLTSLKFDLASVKR
                     SVASRSKALGPRSQERLARALETTDLLFVRLRQIVRALRPPVLEELGLKAALEALIAD
                     VQARTRLRCSLVFEQGEGGPSRCPTLETAFYRIVQELLTNVIRHARATTVAIAITSGQ
                     QNWQMTVQDDGIGFDVAGLAPTGGFGLRGIRERVEILGGQVDILSSSETGTRVHVVIP
                     VSSEPEPACETQHETTASRRRRRKTVDE"
     gene            22895..23533
                     /locus_tag="PK063_11275"
     CDS             22895..23533
                     /locus_tag="PK063_11275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ97680.1"
                     /translation="MNKCRCLIADDHPVVRRGVRDLLEDEQLCSEILEAETGEEALDA
                     VRRQPWDLMILDIALPDKHGLDVLKEAKLLQPRLPVLMLSLYPEKEFAMRAIRAGASG
                     YLTKQSAPSELLAAVSRVLQGGRYITAALAEQLAQAFETGTEGELHARLSDRELQVLR
                     LLGQGKSVSMIGEELCLSVKTISTYRARILEKLSCESTGELIRYAIEARLID"
     gene            23689..24369
                     /locus_tag="PK063_11280"
     CDS             23689..24369
                     /locus_tag="PK063_11280"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ97681.1"
                     /translation="MEQQSVYRIVLIDDSRMVRLGIREQLLTATDFRVVGEAMSAVEG
                     MELVEQVKPDLVLLDSRLPDLSGVEACRTMVARNPAQRVLMLSIQDDPAVVQEAIVAG
                     ARGYLLKDAPVDTWLDAVRRVASGDVLFQPHLLGMVLREVHDMGNGLSSKSLAALSPQ
                     EYRLLPLVAEGKTNKEIASALALSDKTVKNYLANIFSKLGISRRTQAATLYARALPSR
                     SMSSGHYV"
     gene            24388..24771
                     /locus_tag="PK063_11285"
     CDS             24388..24771
                     /locus_tag="PK063_11285"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ97682.1"
                     /translation="MPLILIADDNQQICGWLRAVLEAEGYRVIQASDGREAMATIERD
                     APDLMILDMYLPVQDGLETILMLHNAQSSVKILGISGQPLQGCDILKIAMAFGAHGVL
                     EKPFSRELLLRQVQTLLSSVQLPSV"
     gene            complement(24802..28800)
                     /locus_tag="PK063_11290"
     CDS             complement(24802..28800)
                     /locus_tag="PK063_11290"
                     /inference="COORDINATES: protein motif:HMM:NF013862.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HMZ97683.1"
                     /translation="MTTPGPEKDTYLTVANILGEETELLHGPFSDDHPLKVLERAAPT
                     EASDKRYLDELNRHIHACHPKRAGLCLSGGGIRSATFGLGVLQSLARLQLLDKFDFLS
                     TVSGGGYIGSWLTAWIHRHPRGLKGVIEDLNRPSKAGSEEASLPVRWLRNYSNYLSPH
                     LGFFSADSWTLLGIYLRNLHLNWMVLLPLLMMPLLAPRWIIALAQLNAKETSPPPISA
                     ASLLVIGIGLAVMALIYLHLCRPTLREFRRDTWWQTLESQRWFLIACLCPLLISVTCL
                     TTAWAWFRNGGGGADQFTWAHAVFGGALIHTVSWLFSAVALKRFRAFTRWLLLETLAV
                     AFTGALGGWLLRASFIKTCGQWNVASHAEWFATLAVPGVLTIFLLTATIFVGLASRFT
                     EEQDREWWGRTGSWVLIAMVMWSGLCAIVIFGPGLIHWMTPQVAASVGGLSGLLTLFL
                     GFSSRTTAQQQEERSTVTAVTDLAVRAAAPLFMVCVLIALALGTSWQLDLLAHHYHMH
                     LNHLDGPMQTGLGIGSDPWGHDQILHNTPWWLLFRFTATVVALGLLMSVFININRFSL
                     HAMYRNRLIRAYLGASRRQAERERTFNPFTGFDNLDNPSVSDLRFDDVRLARWFSAQE
                     QKQPTMQALLSYLQLSNPTDEQQEALCAQLPQDLRQTQACKRLSEAAHQLRLGPACVA
                     KLTALQMPDTAAGREASKWFSDLFIHKLHVQSPGPFHVINIALNLVKGDNLAWQQRKA
                     QSFTISPLHSGSWNLGYRRSEEYGANRYIGQPLSLGTALAISGAAASPNMGYHSSSAV
                     TFLLALFNIRLGWWLGNPGRAGADTYHQASPTLSIRPLLAEAFGLTDSCHPYVYLSDG
                     GHFENLGLYEMVLRRCHCILVVDAGCDPRLTFEDLGNAIRKIRIDLGIDIELNLDQIK
                     RAEGATTSNRHHAIGTIRYDKVDDNATAGTLIYLKPSLTGNEPSDVQDYAARHSAFPH
                     EPTSDQFFDEAQFESYRRLGEHIAQEVLRPALHRTEQDFSRLCHALRSHWVTTPPGMQ
                     ESFLGETDDLKDLERLLRDDPDLLRYDMEIYPELCSVFGLDCGNVALNPRAALHTCNL
                     QIQLMEQVYLAVKLEEFHGHALNRGWMNLFRRWTSSATFRMFWPTVCSMYSQPFVRFA
                     GQHFNLSIDQVAVLQPLEQTGDLSSLFRELLIEWASVPDYAETFMNALKRPLPLEEVT
                     DGPPPPLAAWQMRLPAIDSQAGPVGSGEILAVVAVTRLSVTGHRLALYGWVRPAYRGL
                     GLGHRLFGKAIDVLTEVYSGHNLIVDLGPDNAAWAGTSIRNVGWLRFYEQLGFTRDRS
                     DPKRFQMMRELS"
     gene            complement(29067..29624)
                     /locus_tag="PK063_11295"
     CDS             complement(29067..29624)
                     /locus_tag="PK063_11295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00645 family protein"
                     /protein_id="HMZ97684.1"
                     /translation="MSHPSPSHTPSAPSTAAHRVEQLFEILIFGSRWIQAPLYGGLIV
                     AELLYAAKFLTELWHMIVHFREESETLFMLGVLSLIDVTMVANLLTMVIIGGYATFVS
                     KLDLETHPDRPEWLTHVDPGTIKIKLAASLVGISSIHLLKAFVDVTNENPEHIKWKIF
                     IHMTFLGSAIFLAYTDKLMQRDRKH"
     gene            complement(29769..>30998)
                     /locus_tag="PK063_11300"
     CDS             complement(29769..>30998)
                     /locus_tag="PK063_11300"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ97685.1"
                     /translation="VGNAIKFTEHGEVLIQVLQTDEDPGSVVLRFEVIDTGIGLSPEA
                     QAKMFQAFTQADSSTARKYGGTGLGLTICKRLVELMGGTIGLQSFAGQGTCVWFTIRL
                     GTHTDAAPAVPPIPSGLDLTGLRVCLVDDNATNRSLLQYHVSAWNMHHESAVDGPSAL
                     ALLRRGVEEGTPFDVAIIDMYMPEMNGLELCRLIKQDPALRKTHLIMLTASGQRGDSL
                     AAQEAGAAAYLTKPIRERHLADCIRLIFGRDNAKEQPAPFLTRHTITEAIAREAPRLL
                     VVDDNPVNQKVAVKMLEKLGCRVDLAGNGMEALAAICRHQYPLVFMDCQMPDLDGLET
                     TRLLRSQEKPGEHLPVIAMTANAMEGDRESCLKAGMDDFISKPIITSDLKKILARWVP
                     QNQLEGEQAASPETPSS"
BASE COUNT         6332 a         8666 c         9647 g         5953 t
ORIGIN      
        1 ggtcccaaag agtatgccac gttgaagaat ctggccggga aggattggag taatgatatt
       61 gaaagtgtga ttgtcggttc caatgccacg gtgcgtgcct atgaagacaa agacttcaag
      121 gggacggaaa tcgcctttgc gccgggacag cgtgtgccga atctgggcaa gctggatatg
      181 gcgaacgaca tcgagtcgct gaagatcacc tgcggaaagt gagacagggg aagagaaccg
      241 gtccggcctt cagtggaacc agcggtcgta catatagaac aaatcgagcg tcaagcgggc
      301 gccgaaggtc gggccgtaat ctttctggtt gatgaggtcg ttccacgttt cgaaggtgaa
      361 cgcggagtag cgcaacgcca gtgacacaaa ccgttcttcc agcgcgtccc cccggtggtc
      421 cacgaacaga ccggaatcga cggtcacagc cagttcaatt tcccacgggg tacaatcttt
      481 ccagtggtga tagttgccta agcccaccga cgcctgggcg aggtacgatt gcggggcgac
      541 ctggtgaaac gccgcgccgc tgaatggtcg gccatatcgt gccagtccgg agacccggag
      601 atagtcgccg agcacgggaa tcagattgag aatcgccagt cggcgaaatc ctgcctgaac
      661 gtacggctca taatataagg atccgcccgc cccgcctacg ccggcgaaaa acacctcgct
      721 ggtccccaag agcccaaacc agcgcgtcat ggtcccgctc agcataaaat cattggcgtc
      781 acgtttttcg ccgaccggca ccgggtcgaa gccgcgcaac ttatggacga catcgttttg
      841 caagaaccgg ctcggcccgt cacgggtggg gccgccgcct gcggtgaggt tgagattcca
      901 gccgggcaat tgggtaagcg gtttcgtcca gctgatggtg aaaaagttga accccatagt
      961 ctggttaatg tcgttatagc gtctccctgc tccgtcgaat tgcgtaaacc gatccaggac
     1021 ggcggtactc agggtcaggg tggggtcatg gtcgggaaac gcgatcgcgc cccaatgtac
     1081 gctttggggc ggggattcag cgaagaccag actgggaatt gtgcagagcg cgaaggcgag
     1141 cgcaacgatc catcgacgat tcataggcgc gcgcatcctg ccagtatcgc catcacgttg
     1201 gcaactgttc tttgcggagg aacgatcaag gaaggcacga ttggtagctg tcgagtgcgc
     1261 cggctacttg cccagaaatt cgccgatggg ttgcaggggt tcgaggtgat cgcacatgat
     1321 tttgaatgca gcgagtaggg ggacggccag gagcgctccg ccgacgcccc agatccagcc
     1381 ccagatcata atagccagga ccaggacgac cgggttgctt tccaagcgcc gccccaaaat
     1441 catcggcgac gcgaaggatc cttccagaat ggccaggccc caatagacac cgccgatgag
     1501 aaacatttgt ccgagatcgt cgaacgtcaa cgccgccacc aacatcacca ccacgatgcc
     1561 gaagatgtgg ccgatgtacg gaatgaaggt taagaggccg gccatgaccc cccacaggat
     1621 cgggtttggc attccgagca ggtacatagc gatgccgacg gcggtgccca gtgcgaggtt
     1681 gatcccggtg acggtaaata ggtagaggaa gagctgttct tccatgttcc gcacaatttc
     1741 cacggcctgc tttttgtcgc tcaggcgcgg caataccttc acgagctttt gcaggaagag
     1801 atcgcccgac gagagcagaa aatacagaag catgaccgtc gtcgcgaagc ccatcatgag
     1861 ctcgccggtg aggctaaaga ccttgatggg ccaggcatct cctttcactt cgacctgctg
     1921 cacctttttc gtctcatcca aggcggtggc cttcgataac agttcggtgg ctttcgtcac
     1981 atcctgcatc gattttttga ccggctgaat tttgtattca accgtccgca atgccaccgg
     2041 cactttggtg ctccactccg ctgccggttc cgccagacgc gagnnnnnnn nnnnnnnnnn
     2101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2161 nnnnnnnnnn nnnnnnnnnn nnnatggtcc ctgctctgag gtagtcgccc gcgccgctcc
     2221 ggcggacgta gtccatcatt aagtactgat cgaggttgtt gggaataccc aacaccggct
     2281 tgccggccgc cagggcttga tagacggtcg cgctccctcc attacaaatg accagatccg
     2341 ctcgcgcggc ggctgcttgg ccaggcagat actgtgcgac ccgcgtaccg ggtggaagcc
     2401 gtccgggaat ggagcgaccg gcggtggaca ccaaggcttc gataccaagt tgctccagtg
     2461 cgtccagaat gaggggcaag aggtcggccc gtccggacgt gccgagggtg acgtaggcca
     2521 tccgtcccgt atcaggcaat gagtcccacc atcgaggaac cgagtccggc gaccagagaa
     2581 ccggaccgag atagtgatgg tgcggcggtc gatgataggt cggaacaagc tccggcacat
     2641 cggcgtagag cgtcacgtcg gcgtctgtga actggtgcgg caggctgtac gggagtgccg
     2701 gcaatccata gtcgcggcga acctggttca aggcatgtcc ctgctgggcg aaaacaaatg
     2761 gacgcatcat ggtgaagagt gcttgtccca ggcgcgggcc gaagcgctct gtgatggcca
     2821 attcgggaac gacgaaatgc tggtgtgcga acgggctcca atgggcattg gtcaccgtga
     2881 ggtagggaac ggcagcgact ctggcactca cggacagcga cagacgaaag tctccgacca
     2941 ccgcgtccgg cctcacatga gcaaacaggc acagatcgtc ttcgacgtat cggtgtaatt
     3001 cctccttgct atagagcgga tcccctcgac gtaggcgatc ctgaaattgc gcgccgctga
     3061 tcgttcgaat cgggtgcatc gtggcaggca ccgattcgaa gagatggtga tagcgccgat
     3121 cacaggcgag atgcacctca tattggtcag gatcaagact gcgggccaag gccaccgcac
     3181 gggcgacatg ggccagcgtg accgcctccg ccagaaagag aatgcgaggc ttttgtgccg
     3241 acgccagcac ttgaggagtt cccgctccat ctggagaggg aacagccggg ccgagagccc
     3301 gtcgccggcg gacggttgtg ccgggcgccc tcagccagtc ggagagaatt ttatcggtga
     3361 ccatccgggt gatggcggca atatcgcgtc cgctttggaa gtggctttgt cgcagatgcc
     3421 gtccatagat ggcagaaatg gggaccgatc ggatgggaat gccagaccga ccggcctcga
     3481 tcaggatttc gctttcaaac acgaatccgg aagccgcatc gcaaggccac ccagccgccg
     3541 tccaggcgga aatcggatag agccgaaatc cagactgact gtcttcgatc gtacagcctg
     3601 ctgccaggga gatccagaag tccgcaatcc gctgtgcaag tacgcggagt cgcggaatcg
     3661 tgtggcgatg ccggcgcctc gctgcgacga cgattgcgcg cgggtcccgg cggtgcatgg
     3721 cgagtaaggc ggggatggcg gctggatcat gctggccgtc cccgtcgagt gtgataatcg
     3781 ccgtagcccc ttgcgcgacg gcatgctgca tccctcgtcg gagcgcggcg gccttgccca
     3841 aattgttcgc atgtcgcagg accgtcacgg gcaattcccg cagcgacgac accgtctgat
     3901 cggttgagcc atcatccacc acgacgaccc gctcgacgta atgcaaagtc cgggaggcga
     3961 catggtgaat cgttccggct tcattgtagg cggggatgat ggcaatagcg tccttgtccc
     4021 gttccctcat gcctgggctc cattgatcga gatgatctgg ccggatacat aggccgccgt
     4081 atcggagacg aggaacgaga cgaggccggc cacttcctca acagtgccgg ctcgtttcat
     4141 cgggaccagt cgctcgatgg cttctgcgcc gaatgtgtcg agcgacgccg gcgtggagat
     4201 aatgccgggc gcgacggcat tcacggtgat gtgacgtgag gcgagttcca gcgccagggc
     4261 tttcgtggcg ccatggagac cggctttcgc cgcggcgtag ttcacctggc cgcgattgcc
     4321 gatgagcccg ctgacagacg tgatggtgac gatacgcccc caccgggtcc ggatcatggg
     4381 cagcaggagt ggctgcgtca catgaaaaaa tccgttcagt gacacatcga gcaccctgtg
     4441 ccactggtcg ttcgtcatcc ccgccatcgg cgcgtcgtca tagataccgg cgttgttcac
     4501 gaggacttga atggggccgg ctggttgcag gcgatctaag gcctggcggg tttgcgctgc
     4561 atccgtgaca tcgaagcaca gggcctcggc cttcccgccc ttgtcacgga tggcctgcgc
     4621 cacggcctcc gcccgatcca tgcgggtgca tccgtggaca atgacctcga atccggcctc
     4681 gcccagcacc tgacagacgg cttgcccgat gccgccgctg cctcccgtca ccagcgcacg
     4741 cttactcatg cggctccttc ctgtgagacg gatcgagcct cgccagaatg atccgcctcc
     4801 agcatcacgg aaaggcggcc agtcaacagc gtttgtccat ctgcggtcac cgtgacgtcg
     4861 tagatacggc cttgctggtg gctcaactgc agcatcgcaa cgatcgtgag cgcccccttc
     4921 agcccatcca agtgagacag cgtcgtggtg acgtgacgga gcgaagccag cacaccttcc
     4981 gccgcgcgtt gtctatgccc actcccgagc aacgtcgcat gcgcggcaat ggcctgcgcg
     5041 ccgtattcga tcgcgcagag ggtacgaagg ccgctgccgt ctcgtaaggg attgtccgga
     5101 cgaaggtggc tcgtggcacg gcagacgata tggtgttcgt cccatgtttc gactgagtcg
     5161 agcaggcaca tggttccgcg atgaggaacc agctcggcga tgtcgtcaca gcggcgttcc
     5221 atcaatgacc ctccggtttg cagtcgatca cgaggtcgct ctcgtccgtg tactcgagcc
     5281 gcacggtgtc tgcggcctgt cgggccagca gggccaacag gggtaagctg cgcgccgccg
     5341 ggttgctgcg cagcgactcg ggtatggtag cgggaaaggc cgtgatggcc tgatgcgggg
     5401 ccagcgcgat ctcgcaccgc atgcacgcat cgggatggct tgtcggagtc attaaaagcg
     5461 ccgcggcgaa actttcttcc acggggcgaa ttccatacag aggcctgggg aagggcagat
     5521 cggacgcgac caacatcacc gggcagcgct cgacggtggt ataggtggcc gcttcgagga
     5581 gtccggcggc gaacgacaca tcgtaggcgc agacactcgt cgatgagagt tgcgagcggg
     5641 ttgcaatgct ccaatagccg gccggggcgt tgtagacgga gttatgaaac gacgtggggg
     5701 atacctcacg tgcggcaccc gccagtgatt cgcatatctc ttgtgtgatg gccccgtcac
     5761 catccgaaga cgtaaagacg gtggcgatcg cctctccctg gagaggtcct gccagcaagg
     5821 cgtcctgcgc cgccgcgatc gcaagacgtg cggattggct acagcggcgg cgttcggcgg
     5881 cggacaacag cttgagatta ggaggtgtga gaggcgcagg ccggtattcg gtttcaccgg
     5941 ccaggatggg tcgagcagca gcccatccgt ccagcccggg gccggcgatc ccgatgcnnn
     6001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnccg gtcctctcct tcgtcgaact
     6121 acacggcgtt ctttctccga acgttttcca gatggcccgg tcttccgcga gatcattggc
     6181 tggcgttccg gtgccatgca gattgatgta atcgatatcg atgggtttca actccgcccg
     6241 gtcgagcgcg cgttccatag ccaagacagc acccaggcct tccgggtgcg gcgtggacat
     6301 atggtgggcg tcgctgcttt cgccgtaacc cagaaaccgc aaaccgctgt cgcgggtggt
     6361 ctcgcgttcc agcaaaagga atcccgcggc ttccccgatg gaaagcccgt ctcgatgttc
     6421 gtcgcaggga cgacaggggc gaggcgacag caggcccagg gaggcaaacc catagagcgt
     6481 catgaagcac aaactgtcca cgccgcccac cacgacggca tcacagagcc ccgctgccat
     6541 ccagcgcgag gcgctcgcga agactttggc gcttgaggaa caggccgtgg aaatcgatgc
     6601 gaccgggccg gtgagtttca agtgacgccg cacgacatcg ctcacggaga acaaattctg
     6661 tgtgtggcga tagcgcacag tcagcgggag caattcaccc ccggccgcgc ggcgtcgata
     6721 ggcccattcg gtttcgagaa tgccggaggt cgtcgtgccg atgagtacgc cgatgcgatc
     6781 cggcccgtac cgctgccgcg ccgaggcgac cgcctgttca aacccatcct gtcgtaaccc
     6841 gaccagcgcc aatcgattgt tgcggcaatc gaaatcggcg agttcgccgg taatcggttc
     6901 cgtttcgagt ccttcgatcc ggccgatcca ggtcttgatg tccgcatctt cgaagtcatt
     6961 cggccgcaaa ccctgtcgct ccgtgcgcag cgcctgccac gtctccgcca gccccagtcc
     7021 gagcgggttg gcagtggcca tggcggtgac ggtcaatgga gccatcattg cgacacccgt
     7081 tgttggccga ggatcgcggc aatgagtaag gaccctgccg cgccgagacc aacggtgagc
     7141 ccgatggcat gcagcacggg tgtgcgagaa aaggccaggg ccccgaacgc cgacagggtg
     7201 gccgccatgc agaccgtgag cgaaagccag gtccgtcgtt tctcctcctc atctgagaag
     7261 ggccggttga agaacagcgc gtaattgagc ccgatgccca acacgagcaa gagcgacacc
     7321 agatgaaaga gggagaggcg ttcgccgatc acggtgagca gggtcacgac aaacaggata
     7381 gccagcagcg gtggtaacag cacgcggctc accagcgcca tgtcccgcag tccccaccac
     7441 aggagtatcg tcatggccac cactccaagg gcggtcagcc gtaaggattc atgccggtac
     7501 ccgttgacca gccgccccgc ttcggatttc agatcgagga aagtgagtcc gggccccgcc
     7561 tcccgagcaa ggcggtcggc cagaccggag ggagaggtca cgtggcgcag gggcacgaga
     7621 cccgcccacg catcatcagt gtgaaccaga agcgaccgga ttttgagaaa gaagggcgtc
     7681 tgttgaagat tgacgatatc gatcaatgga ctcgtgcggg ccatctcgac atcgtgcaaa
     7741 aacggctcga acagtccggc cctgaaggga agtcctttca ctgcctcagc caatgatgca
     7801 gccagcacat cggaagaagg cagtgcggcc tgccgttttc gttgagaggc atccgacggg
     7861 agatacagac tcggcaggtc gaacccggcc aacagtccgt cgtccaccaa gcggcgcaga
     7921 ggcagttcag cggattcact gcgttgcagg acctcttcct tgctcgagcc ctcgacgatc
     7981 agcacatacc gaacatccgg cgcgccgagg tcttttcgca gttgctcatc gagggttttt
     8041 gacggcgatg caatcggact caaattagcg aggtcgttat cccagatgtt ttcatgtcgc
     8101 attgccaggg tggccagggc cagcagggcc gccacccata tggtccagcg aatgcgattc
     8161 accgatgcca gagcaggcag ccatgacatc ggaagcagct ggtgtggagc ggaccggatg
     8221 actccgggcg gcagggcggg aaggatccag cgcgtcacga atccggctac gagaaccccc
     8281 acgaatgcca gtacgcccaa ctgcgccagg ccggtgatac tcgaaaacag caagctgagc
     8341 gcgccgaaga ccgtggtcag tacggccagt ttcaacgtcg gccatatcct cgacagggtc
     8401 tgctgcagtc gttctcctgc gatgccctgt gtgaagacgt aggcggggta gtcgaccgct
     8461 tctccaatca gtgtggcgcc gaaacccagt gtgatgccat ggacgaaccc gaaccaggtt
     8521 tgtaccgccg ccactccgac gagcaagccg gtcaacaccg gaaggaggct cagcaggaga
     8581 ggcgtcaccg accggtagac gagaaacagc agaatcgtca ccactgtgat ggcgatgacg
     8641 gacagtcgcc aagagtcgcg ctggatcgtg gcgcgggatt ccaccgcgaa tacgccgggg
     8701 ccggtcatga ccagatgggc atgttccggc aggccggctg atgtgaatgc cgtccgcacg
     8761 gcctgcactg ccgactcctg ctgatcgagg gcaaaccctg gcgcgctggt ttcagcgacg
     8821 agcagggctc tggttccgtc gcgggaaaac cagacgccct ggtgcatcga cggtccttcc
     8881 cccggggtga aggccgccag tatgtgaggc acttcaccgg tgggatcgga gggcaaggcg
     8941 gtcttcatca gcgcaccggc cggagaggcg agaaattgca gctgtcgttc caatgcctcc
     9001 cgcaatgccg ttgccgtgaa atgctccggg atgacggccg cactcagaag gtaccgatgg
     9061 cgcatcagca cctcacggac gatggtgaag tcggcggggt ctccgttgtt taccgaggcg
     9121 aagaggcccg tgtctcgtaa tttgcgggct atggttcggc tggcttgggc cagcgcctcg
     9181 ccctcggcgc ccgagaggcc gatcaggatc agtcgggccg cgacgccgtc ccggagttgc
     9241 gacaccagca gctcctgccg atggtcagcg gagcggggca gcaaggcggt caagtcggtg
     9301 gtcatcgtca tgttggcaac gattcctccg ctgataaaca ccagcagcat ccagaggaac
     9361 agggccggtc gggcatgcag ggtcacgaga ccggcccatc gatctccatc aaggaccggt
     9421 cccctccggt ttcccgtatg tcgaccgttg ttaaacgatc gccctctcct cgaaggatga
     9481 tcgaggccac gtattccgcc gcttgcgcat ctaacggccg cagcgtgagt tcccactgct
     9541 ggcgggtgcc ctgaaacttg atgtggtaga gccgccgcaa tacggcaagt tctcccgcca
     9601 gactggcccg gatcgcttcg atgaaggagc gaatcaacgg gtggctatca acggcaatct
     9661 gctttgtgcc cttcggtgag gacagcgtca gccgatcgcc ttgcaccgtg agatcctccg
     9721 tatagggcga ggtgatatgt ttctcgacgc ggtctggacg aacataagcc agcgtgcctt
     9781 tgagcaccac cggctgagtc aacatggcga tggttttcgt ttccgtgaaa cggtcctggc
     9841 gggacgagac cttggccagc agttccatca gtccgggcac gtcgaatggc tccgcgccca
     9901 tggcaggttc agcggacgcc ggcagccagg cccacaggct acacagcagg atgagagggc
     9961 tgagcgtgat cgggaccttc ataaaagttg aaccagttat acggagatac acggcagtaa
    10021 tgttccagcc ggctgacgta tcgctcgatc caagggcgta gggtttccga tcggcgggcg
    10081 ccattcacag gaatagtgtc ggccaagggc tcaaaataca ggtggtatcg gcggcccccc
    10141 tggtagagac caaaaaacag cacgatcggc acctggagca gcgcggcgag cagaaatggc
    10201 ccttcgggga acatgcgggt tttgccgagg aactcgcagg ccatgccttt ttcatcgttg
    10261 aacaggcggt cgccgagaat ccccacgatt tcccctcgat ccaatcgttc tttgaccgcc
    10321 agcatcgtgt cggcggttcc aggcggaata atccggtccc ggatctcggg gcgcaggttg
    10381 tgcagcactt cgtttaagtt ggaggctgcg gcttcgtgca tgatcaccgt gatcggcagc
    10441 ttgtgatcga agatgccttg cgcgcgcagg acttcgaaac tgccgaggtg agaacccagc
    10501 aaaatgcagc ctcgattctg ggcgagaacg gcatgtaatg ccgaagcgcc ttcggtgtga
    10561 atatcgaagt agcgatggcg tccggacagc agatacaccc nnnnnnnnnn nnnnnnnnnn
    10621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10681 nnnnnnnnnn nnnnnnnnnn caagacgagc agccgcatca gccttcgact tcctcgttcc
    10741 ggctgatggc gccagccggt gctcatgatg cgacctgcgt ggtgacgcga gcgcgatgga
    10801 ccgtgcctgt ggcgatcatg tcctcaccac gcgtcacggc aaaggcgatg tcctggttag
    10861 gcaggaatcg ccaccgcagc gtgaagggtt cttcaggccg aagcagtcga aggaatttca
    10921 ccgagctcag ttcgaggggg ccaggtttca taccggcttc ttgttcaagg atgctcagca
    10981 attcggttaa gagcaccact cccgggacga gagggttgcc aggaaaatgc ccggccaaag
    11041 ccgggtggtc ccggcggatc tgtcgcggtt tctctgtgcg catgcgttac tcgtgaacgt
    11101 gctgttgggg atgcatgatg tgtcgggcaa aggttttcaa atgttcgtgt ggtaatttgc
    11161 cggtggtgtt cctggggagc tgatccacca catataacgg gcggggaaga aagaccgggt
    11221 cgatacgttt ccggagctcg gcaagaatcg ctgcacgagt catccccggc gcgaccacga
    11281 aagctctcaa tctgccggtg cctgtttgtc ctgggtcggg ccaataaaac gtgccgtcca
    11341 ccacaccggg aatgcggttc aggattgcat tgagcgccgt caaggaggcg cgttttcccg
    11401 ctaccttcac gaggtcacgg tgtggcccca ggaggaggaa ttcccgctga ctgcggagcg
    11461 tgatgcggtc cgacagctgg agccaggctc ccacatgtcc gcccatgacc caggtcgtgt
    11521 cttcggcatg ccgcatccgt aaatcgtggc acagcgtcca ggcttcaccg gccgttgtgc
    11581 ggcgcgacgc gagcatcccc ccttccgtgc atccatagat ttcatgtacg ggcacgtgcc
    11641 acagccgttc cgcgctgagc gcgattgccc ggtccagggg catcgtggcc gagatgatgc
    11701 cctcaaggcc gcgcaggttc gtgcgttcgc ggagaaacgc cttgagatgg aagggcgttg
    11761 tcatcaacca ggccggcgat tccagttgct ccaggtccgt ccgaaggtcc gcggggagga
    11821 ttgaagtgcc ggcgtgcaca ctccatcccc attgaagcgg cagcatgatc gtggtttcca
    11881 acccatacat gtgctgggca gggacggttc ccacagccac cctcgacgaa gactgcgtca
    11941 ggccgaactg ttgccccaat gcgcgcgcgc ccatgaccag ggatccccag cttttcgcat
    12001 gagcctgagg gaacccgcta ctgccggagg tgaacgcgat ggcggcgatc tgatcggcgg
    12061 gaatcaccgg aacatctttc ggaccgaccc cctgctccat ttctcgaagg agggagaagc
    12121 gaggtatggg gatatccccc tcgtcatgat cggtcagcac atatgcaccg ggatactgtc
    12181 gcgcgagttg ttgaaggggt tctgccgcgc ggcaggtggg caacagactg atctgacgtg
    12241 cgatcaaggc cgcggcaaat cccacggcga agtggtagcg atcccggcaa agattgatgg
    12301 caaagtgttt gcgcggcaac tgcgccgcga gacttattgc agcacacaga aactcgtgaa
    12361 cggaatgtgc acgatcacgg cgccaggcga gcgggctcgt tacggaatga tgtcccacga
    12421 ggggataccc ggctgccgct ctcggctggt gcatgcgccg ggcgggggag gccggagcca
    12481 tctggctgtc gatcgattgc atcatcatcg aatccgatgt tgggcaatgt gattcgccaa
    12541 tgcccggagc gaagccaggg ccgctttatt ctccgagcgc aattccacgc cataacgttt
    12601 ggataccaac agggcgattt ccagcatgtc gatggaatcc agccctagcc cctcgccgaa
    12661 gagtgccgag gacggatcga tggtctcggg taacacttcc aagcggagtg cctccacgat
    12721 gagggtggcc agttcctgct ccaacgcgcc gtcggcgccc acctgggatt gcgaggaaaa
    12781 cgccatatca ctgcgcctcc tggataaggg ccggattgcg ctccgtaccc gtgctggttt
    12841 tggcgcaccg aagcgccgcg gctaataatt cgtcgggatc atcgatgaag ggcttggaat
    12901 gtaaggggag gcccaaccgc gcggcctcct cgaccagaag gctgagatag tcgccgaggt
    12961 gttctgccgt gaaggagttc gtatcgtgaa aggtcaccac gatgggaatg gtgtgattca
    13021 ccaccggcaa cgttccccga agaaagcggg catgtaaccc agccagctgc gagcggaaat
    13081 tcagccttcg cagcaggtgg atgccccagt tcaccccgtc gaaggctttg acatcggaca
    13141 acagcatgtg aagccgatgc cgtccatagc agtcgaaggt tgacgcgttg aacagccagt
    13201 atggagggcg gaccagcatc gtcggcttgc cggtgatctg gtcgaggtcc tctttgccgt
    13261 tgagcagtga ccgctcgagt tcagccggcg acatgcgagt gtgactgagg tgccctttcg
    13321 tggtccccgt atgcaacccc aaaaggtgcc cctcggcttg ttcaatcgcc agcatggctc
    13381 gcccatcgga tgagccccct cgcttcgggt ggcgcgtctg cacgaaaaat attcctttga
    13441 tgtgcggttg caccggattg cgggcgaggt gccgcaggac tttcccggtg ttgggatggg
    13501 gcccgtcatc aaaggtcacc aggaagcgca gggtcagagg cgcatctgca ggccgtcgcc
    13561 cgcccaaccc ctcgtttgtc gctgagtgcc gcatcgatac ggtgttcacg tgtcagcctt
    13621 tcgtgaatta tcgtttggcc accactttcc ccgtgcacat gtacgtgttc gtgtagatcc
    13681 aggaaatggg gcccgaggac ggctgctgct ggacgtcggt caggcgaacg tccacgttca
    13741 aattcttggc atcctccttg agattttcga tacatccctg aggagagcgg ccgctggaaa
    13801 tcaccttttc gatttcattc gtgtcgtaat ttggaatggt gtagtgaggc ccgcatccgg
    13861 tcagcaagac tgcgattcca agtgcccacc ctctgctcat gtccaatctc ccctcgttga
    13921 cggtaaaaaa gtccggcctg tcagggtttg actgtatgaa actgagacga agacccacac
    13981 tgggggcctc cctagtttgg ccctaggagc ccccgagttt gctgaggcga atgccggtgc
    14041 cgttgcttgc ggacatttct gtcaatcaat acaatggcct cgaccaatcc ggtcacacgt
    14101 gcattgccat gcgaggagga attatgccag ccaagaaggg atcaacggct cgcccgtctg
    14161 ccgcagcgaa ccaagggcaa ccgacggagg agtttgagaa gctcggggtc ttttatctcg
    14221 gccggcccta tgcgctcgtg acgaagcaat ccaggccggg atggctgctg tatgattcga
    14281 aggacctggt gacccatgcc gtgtgtgtgg gcatgacggg gagcgggaag accggcctgt
    14341 gcgtcggact cttggaagaa gccgccattg atggcattcc ggccatcgtc atcgatccca
    14401 agggagatct ctccaatctt ctcctgacgt tcccgcaact gcgcggcgaa gactttgccc
    14461 cctggatcaa cgaggacgat gcccgcaaga aaggactttc gcctgccgac tacgcgaccc
    14521 aacaagctgc gttgtggcag aaaggcttag gcgaatgggg tcagagcggc gagcggattc
    14581 aaaagttgcg cgatgcggcg gacgtcgtca tctatacgcc cggcagcaat gcgggtctgc
    14641 cggtgtcgat cctcaaatcc tttgcggcgc cttcacccga gttcctcgat gatgcggaac
    14701 ttttgcgcga gaggatttcc acgacggtta ccagtgtgtt gggactcatc ggtctccagg
    14761 ctgatcccat caaaagtcgt gaacatatat tgttgtcgtc gattcttgac agtgcctggc
    14821 gggctgggcg tgacctggac ctggcggcgc taatccatca gattcaaacg cctcccatga
    14881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn gggcgtgacc tggacctggc
    15001 ggcgctaatc catcagattc aaacgcctcc catgaccaaa gtcggggtac tggatgtgga
    15061 atcattcttc ccttcgaaag aacgattcgc cctggccatg caattgaaca atctgctggc
    15121 cgcgccgggg tttgccgcct ggatggaagg tgaggcgctg gatgtcggac agattttgta
    15181 cgggccgtcc gggaagccgc gcatcgcgat tttttcaatt gcccatttga acgacgcgga
    15241 gcggatgttt tttgtctcac tgctgctcaa ccagacattg gggtgggtcc gttcgcagtc
    15301 cggcaccacc agcctgcgcg cgatcctcta catggacgaa atttttggct actttccgcc
    15361 ggtcgcgaac cctccctcca aagcgcctct gttgacgctg ttgaagcagg cgcgcgcgtt
    15421 cgggctgggt gtcgtgttgg ccacgcaaaa tccggtggat ctcgattata aggggctggc
    15481 caataccggc acctggttca tcggtcgttt gcagacggag cgcgataagg cgcgggtgat
    15541 cgaaggcttg gaaggagcgg cggccagtag cggtaagaag ttcgaccgcc agcagatgga
    15601 acagatcctt gccggtctgg gcaatcgggt ctttctgttg aataacgtgc atgaagatgc
    15661 gccggaagtc tttcaaacac gctggacgct gtcatatctc cgggggccac tgacacgcac
    15721 acagatcaaa cagttgatgg atccggtgaa gcgtcagctg ccagcgcgga cctcacggca
    15781 ggacgaactg ggagccgcag gggcttccgg ctcgacgagt gcggcgtcgc gcacgacggc
    15841 ctcccggcct atgttgcctc ccgatgtgcc gcaatatttt cttccgctcc ggggaacgca
    15901 accaagtggc gcaacgctca tctatcagcc aatggtcttg ggtgctgcgc aggtgcgatt
    15961 taccgacaac aaagcaggga tcgaggccac gaacgatgtc acgcgactgg ctgctatcag
    16021 cagtggcgtc gttccggtcg agtgggaaca gtcgacggcc gcggatgtgc aggtggcgga
    16081 tcttgaacgc gaaccggccg ccgctgcgga gttcgcggct ctgcccggtg cagcgagcaa
    16141 agggaagcaa tacgacagct ggaagagcga cctctccggc tggttgtttc gtacgcaaaa
    16201 gctcgaactc tggcgaagtc cgaccacgaa tacgctatcg aagcccggcg agtcggaacg
    16261 cgattttcgc gtccggttac agcaggttgg ccgggaagag cgtgacaggc tgagcgacga
    16321 gcttcggaaa aaatatgcgc ccaaaattac gacgcttcga gaccgggtcc ggcgcgccga
    16381 gcaggcccgg gagaaacaac agaacgaatc tcgatccagt caggtgcagg cggtcatttc
    16441 tgtcggcgca tcgatactgg gtgcatttct gggccgcaag acactcagcg cgacgaacat
    16501 cggccgtgcg acaacggcga tccgcagcgc ggggcgtgtg atgaaggaat cgcaagaggt
    16561 cggccatgcg gaagaaaacg tggccacgct tcagcaacag ctgacggacc tggaggccca
    16621 gttcaaatcg gaaagcgatg cgctcatggc ggcgacggat cccttgactg aaaagttcga
    16681 gcagatttca ctgaagccca ccaagtcaaa tatcgtcgtc aaactggtgg ggctggcgtg
    16741 ggtgcccgcc tggcgcggcg ccgacggcac ctctgccccg gcctggttgt agccagtccg
    16801 ccacagaggt ggctcgcgcg gtcgcctcta caggaagagt gtcgttccag atggccctag
    16861 tccatcttgg gtatttgtga tatgactcgg ccggatgtat gaatacagcc atttcattct
    16921 ctcgcgcgtg ggagctcacg catggggacg catacgctgc ctcccgatga aaccgcgcgt
    16981 gtaggggccc tgtgccgcta ccgcgtcctc gattctcctc cagaagccga cttcgacgag
    17041 atggtgcaac tggccgcctc gatctataag gctccgattg ccgccatcac gttcatcgat
    17101 cacgaccgcc agtgggtgaa ggccgctgta ggtctggaca ccagccaaac cgaccgtccg
    17161 tctgggctgt gctcttttac cattcaaggg aaagatccga tggtcatcga ggatgcctcg
    17221 gcggatgatc gcttttcatc ccatgcgctg gtccgcggac atccgcatgt cagattttat
    17281 tgcggcgcgc ctctcgtcac tcgagacggg tatgcggtcg gcacgattgc cgtaatggat
    17341 tcgattccgc ggacggtgaa ggaggacgac ctcctgacca ttcgacgatt ggcgcggcag
    17401 actgcggcac tcctggaact gcgcatgctg aggtccgaac gatcatccgt cgactcgctg
    17461 tccacggatg atcaggtgga gaccctgaca gaggcggcct tcgtgatcga tcggagcggc
    17521 cggattcttc gggctaatcg gggggcagag cgtcttctag gcgttttagc ctctgacctc
    17581 agggggcggt tgttgcatga gtgtgtgcac cgtcctggcg atggggatga agaggggcag
    17641 gacggatcgt gcacgttgat gcatgcctgc cttagcggga ccgccgtgct cgaacaggac
    17701 gatgtgttcg tgaacggtga tggctctctg ctgcaggtgc gctggaacca tgtgccgtgc
    17761 tggtctggtg gagactggag cggcggcatc gtcgcggtgc gagatctcac tattcagaaa
    17821 cggaatgagg aggtgctgcg cctgatggcc cccaccacca ggctcacggg cacggcgttc
    17881 cttcaggacc tggtggagac cctggtaaaa acgattggcg cggactacgg tttctgtctt
    17941 cgcgcactgc ccgaagggcg atgcgcgcat tccgtggccg ggtgggggcc gaacggccgg
    18001 ctggatcctg tggactatgc cctcgccggg accccctgcg agcatgtcct ccatgaagga
    18061 ttctgccact actcttccgg cgtccaggcc ttgttcccac aggacgaggt gttggtccac
    18121 ctgtccatcg aatcgtacat ggctctgaca ctgccctcgc cgactggagg gccagttggc
    18181 tggatcgcgc tgctcggtcg atcccccctg aaggatgctg aacgggcgga agccttgctg
    18241 cgtgtggccg ccggtcgtgc ggggagtgaa ctgggtcgcc atcttgcaga ggaacagctc
    18301 aaggagagcg aggagcgcta tgccctggcg cttcgaggga cttctgatgg catctgggat
    18361 tggaatgttc ttgccggtca ggccgttctg tctccgcgct ggaaggcact gctggggttt
    18421 gccgaagacg agttgccgga tcacgaatcc tcgttttttc agcgcgtaca tcccgaagac
    18481 gtgccgcggg tgaaagcgga gattgagaga catttcgccc gccggacccc gtatgacgtg
    18541 caatgccggc tgttacacaa ggacggcacg taccgatggg ttcagacacg ggcccaggcc
    18601 ttatgggatg accagggccg cgcctatcgt atggtcgggg cgtcaaccga tattacggag
    18661 cgcaagcagg ctgaagacgt cgcgcgacgc tggcaacagg tgtttgatca ggcacagctc
    18721 ggtcttgccc acgcggattt ggcaaccaat acctttctgg ccgtgaaccc ggcgttcgcc
    18781 cggcaatgcg ggtacacggt ggaggaattg atcggtcgct caattttttt catctatccc
    18841 ccagaggaac atgccgccct ggaagagcga atccagcgca ttcatgacac gggcggcctg
    18901 acattcgaat ccattcaccg gcgcaaggat ggaagtcttt tcccggtgat ggtcgaggtc
    18961 atgctcatca gggatgccga tggagtgccg gtgtcacgcg tcgcgtacgt gaaggacatc
    19021 acggaagcga agcaggcgga acaggcgaga cgcgcgagtg aagaacgatt tcgtgcggcc
    19081 taccgcaatg cgacagtggg gatgtccatc gcagacgtgg gaggtcgcat ccaggaggtc
    19141 aaccaggctc tctgtaaaat tctcggctat tcagagcagg aactgctggc caacacattt
    19201 caatcgatta cccacccgga cgacctcggg cagaatctcg atcgtattca aacgctctta
    19261 tccggaaggc gggtctatga tgtgtttgaa aagcgatacg tcaggaagga cggaggcgtc
    19321 gtgtgggccc aggtgggtgt atccgtcata cgcgacgagg agggcacccc gctctatacc
    19381 ctcgcaatgg tacaggacat caccgaacgg aagcacgccc aggaagcgct ccagctggcc
    19441 aaatacaccg ttgatagcgc gaccgaggcc atttattggg tcggcgccga cgcggaatta
    19501 ctggatgtga acgattcggc ctgttccatg ctgggctact cgaaagacga atttcggcgg
    19561 atgagagtcc acgacatcaa cccgaacttc caggctgaaa catggccaac cttttgggca
    19621 cacaccaaag aacggggccg tgtctcgttt gagagttgcc atcgtgccaa agatggccgc
    19681 ctgattccca tcgatgtgaa tgtgaacttt gtccattaca acggggtcga atgccatttc
    19741 gcgtttgtgc gggatatcac cgaacgcaaa tcagccgagc gcgcactgcg ggccagtgaa
    19801 gagcggttcc actttgccat tgaggccacc aacgatggca tgtgggactg ggacatgcgg
    19861 acggatgagg tgtactacag cccgcagtgg attcgattgc ttggctatca gtccgaagaa
    19921 gtcctgccca cccgggcatt ttttatgacc cttctgcatc ccgatgatgt cgcccgcatg
    19981 atggacgtgt tgcaggcaca cgtggacggc cgcattcccc tcaaggagat cgaagtccgg
    20041 ctgcgacaga aatccggtga gtttcgatgg tatctgaacc gcggcaaagt cgttgccaga
    20101 gcggaggatg gccgcccgtt gcgcatggtc gggacgatta ccgatatcag cgagcgcaag
    20161 cagtctgagc gtgaacgcga tgaggcgctc agtcatcttg aaacgatcat ggaaaccgtc
    20221 cctgacatca tttttgcgtt ggatctcgag gggcgagtgg ccaaatggaa ccggaaatta
    20281 gaaacggtga cgggctatac gagggaggag ttgcagggta agtcggcgct tgaaatggtg
    20341 ccttccgatg aagcggaaaa aacagccgcg gcgatccgcg aagcctacga gaagggctac
    20401 gccgagttgg agggccatct gttggctaaa gatggccgga ccatgctgta tcactggacc
    20461 ggtgctccct atcgggattt gcaagggcgg gtgatcggtg tcaccggtgt cgggcgagac
    20521 atcaccgagc gcaagaaggt ggagcagatg ctcgcgtcgg aaacccgcat cttggagatg
    20581 atgggatcgg atgctccact gtcggcagtg ctggcagaaa tttgcctgat gatcgaggga
    20641 ctgtccagcg gcgtcctctg ctccgtgttg ctgctggagg aggatgaagc ccacttgcgc
    20701 catggcgccg gtcccagcct tcctgcgtcc tatgctcgaa ttttggacgg gatggccatt
    20761 ggtcctgcgc gcggttcatg cggcacggct gcattcaccg gacagcaagt ggtggtgacg
    20821 gatattgcga gccatccctt ctgggcggac tttcgtgagc tcgccctggc gcatgggctt
    20881 cgagcctgtt ggtcgacccc catcatctcg gcagcaggaa aaatcctcgg cacctttgcc
    20941 atctacaatc agacaccccg tcagccgacc gctgaagcgc cgattgtcgc ccgggcctcg
    21001 catctggcct gcctcgcgat cgaacggaag cgaacggaga gcgccctgcg cctcatgcag
    21061 ttctccattc agcaggcggt ggacgcggtt tttctggtca gtgcggaggc acggattctg
    21121 gatgtcaacg aagcagcctg tgccatgttg ggctataccc gtgaggaact tttatccaag
    21181 accgtgcatg atatcgacac gaatttcacc cgcgaaaact ggcgagcccg ctggcagcat
    21241 ttgaaagtca ggaagtcctt ctcgtacgaa tcccggcatc agaaaaaaga tggaacggtg
    21301 atccagaccg acaccaccat caattttctg gtccacgaag gccgggaata ttattgcgcg
    21361 ttcatgcggg atatcacgaa tcggaagcgg gcggaggcgc agttgcatct gacgcaattc
    21421 gcgatggaac gcgcggctga catggtgttt tgggtggacg aggcagcgcg cctgttgctc
    21481 gtgaatgccg cggcatgcga acggacgggc tacacgaaag acgaattact gcacatggcc
    21541 gtgccggata tcgatcccaa ttatcagatg gaagcctggg tccgccactg gcaggagctt
    21601 cgagagaccg gccgtcagcg cctggaaacg caacatcgat ccaaatcggg cgagatctat
    21661 cccgtggagg tcgtggcgaa tttcgtggtc ttcgaaggac gcgagtataa cttcgccacg
    21721 gttcgggaca tgtctgagcg gcagcgcacg gagcttcggc ttcgatccag cgaggaacgg
    21781 tttcgtctcg tggctcaggc caccaacgac gtgttatggg actgggatct tgtgacgaac
    21841 gcgcattggt ggagccccaa tgcccgggag aagttcgggt acgatcccca gcgggaaccg
    21901 agcattgatg cctggacggt gcggttacat cccgacgata aggcaccgat tctggccatg
    21961 gtccaacagg ccattgagtc ggaggtgcag acgctcgccg cagagtaccg gttcctgctg
    22021 gccgacggga cctatggcta ttttctggat cgggcccaca tcgtgcgaaa tgaggtggga
    22081 atggccatac gcatgatcgg cgccatgatc gatgtgacag gtcccaagcg cgcctatgca
    22141 tcgctcgagg aagcctatcg acgttttcag gccatgtcgc aggaactgca aatggtcgaa
    22201 tccaatgaac gtcgccgtct ctctcgtgag ttgcatgacg aactggggca gttgttgacc
    22261 tcactcaagt tcgatctggc ctccgtcaag cggagtgtcg cctcgcgttc caaagccttg
    22321 ggccctcgaa gccaggaacg attggcccgc gcgttagaaa ctacggatct gctctttgtc
    22381 cgcctgcgtc agatcgtacg ggccctccgg ccaccggtgt tggaagagtt aggactgaag
    22441 gccgcattgg aggccctgat tgccgacgtg caggcgcgca cccggctgcg ctgttcgctg
    22501 gtgttcgagc aaggggaggg gggaccgtca cgctgtccca cgctggaaac cgcgttctac
    22561 cgcattgtgc aagaattgct gaccaatgtc atacgccatg cgcgcgcgac gactgtggcc
    22621 atcgccatta cgagcggcca acagaattgg cagatgacgg tccaggatga cggcatcggt
    22681 ttcgatgtgg cgggactggc tcccaccggg ggattcggct tgcgaggtat acgggaaagg
    22741 gtggaaatat taggcggaca ggtggacatc ctttccagtt cggagacggg aacacgggtg
    22801 catgtggtga ttccggtgag ttcggagccg gagccagcgt gtgaaacaca acatgaaacg
    22861 acggcatcac gtcggcggcg gaggaaaaca gttgatgaat aaatgtcgat gtctgatagc
    22921 cgatgaccat ccggtcgtcc gtcgaggtgt gcgtgattta ctcgaggacg agcagctgtg
    22981 ctcagaaatt ttggaggctg aaaccggaga ggaggcgctc gacgccgtac ggcgtcagcc
    23041 ttgggatctg atgattctcg acatcgcgct gcccgataaa cacgggctgg atgtcttgaa
    23101 ggaggccaag ttgctccaac cccgcttgcc cgtgctgatg ttgagcctct atccggaaaa
    23161 agaattcgca atgcgggcaa tcagggcagg cgcctccggg tatctcacca agcaaagcgc
    23221 gccctccgag ctgctggcgg cggtcagccg ggtgttgcaa ggcggccggt atattaccgc
    23281 cgctcttgcc gaacagctgg cgcaggcctt tgaaaccggg acggaggggg aactccatgc
    23341 gcggctctcc gatcgtgagc tgcaagtcct ccggttgctg ggacagggca aatcggtttc
    23401 gatgatcggg gaagaactgt gcctcagcgt gaaaaccatt agtacgtatc gtgcgagaat
    23461 cctggaaaaa ctgtcgtgcg aaagtaccgg tgaactgatc cgatatgcca tcgaagcgcg
    23521 attgattgat taggtcttag tctttctcct tagagcctcg cctgtccgtt gtggtcgcgt
    23581 cagccgaatg ctgacgcgta aatccacctc ctgcctatat tcctactacg cgaatgtacc
    23641 gaaactagta ccccggcgag gcctcagtgt tatcgcaatg ggggagacat ggagcaacag
    23701 tctgtctatc gcattgtatt gatcgatgat agccggatgg tgcgtctcgg gattcgggaa
    23761 caacttctga cagcgacgga ttttcgcgtg gtgggagaag cgatgtcggc tgtggaaggg
    23821 atggagctgg tggaacaggt caagcctgac ctggtgttac tggatagccg tctgccggat
    23881 ctctcaggcg tagaggcttg ccggacgatg gtcgctcgca atcccgcaca gcgggtgctc
    23941 atgctgagta ttcaggacga tcccgccgtg gttcaggagg ccatcgtcgc cggagcgaga
    24001 ggctatctgc tcaaagatgc gcccgttgac acctggctgg atgccgttcg cagagtggcg
    24061 tccggtgatg tgttgttcca accgcacttg ctcggtatgg tgctgaggga agtgcacgac
    24121 atgggaaatg gcctttcctc caagtcgttg gctgcccttt ctccgcagga ataccggttg
    24181 ttgcccctgg tcgccgaagg caaaacgaac aaggaaatcg cttccgccct cgcgctctcc
    24241 gataaaaccg tcaaaaacta cctcgcgaat attttttcca aactgggaat cagcaggcga
    24301 acgcaggccg cgacactgta cgcgagagct ctgccaagcc ggtccatgtc ttctggccac
    24361 tacgtgtgac agcaaggagg gccctgaatg ccgttgattt tgatcgcgga tgacaaccag
    24421 cagatttgcg ggtggttacg ggctgtcctc gaggcggaag gttatcgtgt catccaggca
    24481 tcagacggcc gggaggcgat ggcgaccatt gagcgagacg cgcctgatct gatgattctg
    24541 gatatgtatt tgccggtgca ggatgggctg gaaaccatcc tgatgctaca caatgcccaa
    24601 tcgtctgtaa aaatcctggg catatccggt cagcccctgc aaggatgcga cattctcaag
    24661 attgcgatgg cgttcggagc ccatggcgtg ctggaaaaac cgttcagtcg tgaattgcta
    24721 cttcgacagg ttcagacgct gctgtcgtcc gtgcaactcc cctcggtctg aacggtacct
    24781 gccctggttc ttttcccggt cctacgaaag ctcccgcatc atctgaaagc gcttgggatc
    24841 cgaacgatcc cgtgtaaatc ccaactgttc atagaaccgg agccatccga cattgcgtat
    24901 ggacgtgccg gcccaggcgg cattgtccgg gcctaaatcg acgatcagat tatggccgga
    24961 atatacctcc gtcagcacat caatggcctt cccgaacaga cgatgcccca gacccaatcc
    25021 ccggtacgca ggacgaaccc aaccatataa ggcgagccgg tgtccggtca cggaaagccg
    25081 agtcacggcg acgacggcca gaatttcacc ggaaccgact ggtccggcct gggagtcgat
    25141 ggccggcaaa cgcatctgcc aggccgccag cggcggtggc gggccatcgg tgacttcctc
    25201 cagcggcagc ggccgcttca gggcattcat gaatgtctcc gcataatcgg gtaccgaggc
    25261 ccattcgatc aataactccc ggaacagcga gctaaggtca ccggtctgct ccagtggctg
    25321 cagcaccgcg acctggtcga ttgaaagatt gaaatgctgc cccgcaaagc gaacgaatgg
    25381 ctggctgtac atgctgcaca cggtgggcca gaacattcgg aacgtcgccg aggaagtcca
    25441 acgccgaaac aggttcatcc atccgcgatt gagcgcatgg ccgtggaact cttccagctt
    25501 caccgcgaga tagacctgtt ccatgagctg aatctgcagg ttgcaggtat ggagcgcggc
    25561 gcgaggattg agggcgacgt tgccgcaatc cagtccgaag acggaacaga gctcgggata
    25621 gatctccatg tcgtagcgca acaggtccgg atcgtcccgc aagagccgct cgaggtcttt
    25681 gagatcatcc gtctcgccga ggaaagactc ctgcattccc ggcggggtcg tcacccagtg
    25741 cgaacgcaac gcatggcaca gtcgtgaaaa gtcctgctcg gtgcgatgga gcgccggcct
    25801 gaggacctct tgcgcgatat gctcacccag acggcgatag gactcgaact gggcctcatc
    25861 gaagaattga tcggaggtcg gctcgtgggg aaatgcggaa tggcgggccg cgtaatcctg
    25921 cacgtcagat ggttcgttgc ccgtcaatga cggtttgaga tagatcaatg tcccggccgt
    25981 ggcattgtca tccaccttgt catagcgaat ggtgccgatg gcatggtggc gattgctcgt
    26041 cgtggcaccc tccgcccgct tgatctggtc caggtttagt tcaatgtcga tcccgagatc
    26101 gattctaatc ttgcgaatgg catttccaag atcctcgaag gtgagacgag gatcgcaccc
    26161 ggcatccacc acgagaatac aatggcagcg gcgcaggacc atttcataca gccccaggtt
    26221 ctcgaaatgt ccgccgtccg agagatagac ataggggtgg caggagtcag tgaggccgaa
    26281 tgcttcagcc agaaggggac gaatcgacag agtcggagag gcttggtggt aggtgtccgc
    26341 gcctgcgcgg ccggggttcc ccagccacca gccgaggcgg atattgaaga gggccagaag
    26401 aaacgtcacc gccgaggacg aatggtatcc catgttggga ctggcggcgg cccctgaaat
    26461 ggccaaggcc gtaccgagcg acagaggttg gccgatgtag cgattggctc cgtattcttc
    26521 agagcgacga tagcccaggt tccaactgcc gctgtggaga ggactaatcg taaatgattg
    26581 agctttccgt tgttgccagg ccaaattatc gcccttgacc aggttgaggg caatgttgat
    26641 cacatggaac gggccaggac tttgtacgtg aagtttgtgt atgaagagat cgctgaacca
    26701 cttggaggcc tcgcgaccgg cggcagtgtc cggcatctgt aaggcggtca gcttcgcgac
    26761 gcacgctgga ccgagacgga gttggtgtgc ggcctcgctg aggcgcttgc atgcctgagt
    26821 ctgtcgcaga tcctgcggga gttgcgcgca caaggcttcc tgttgctcgt ccgtcggatt
    26881 tgataactgt aagtaactga gcagtgcctg catagtcggt tgtttctgct cctgcgcaga
    26941 gaaccaccga gcgaggcgga catcatcaaa acgcaggtcg cttacggacg gattgtcgag
    27001 attgtcgaat ccggtgaagg gattaaacgt tcgttcacgt tctgcctgcc ggcgggacgc
    27061 cccgagatag gctcgaatga gccggttgcg atacatcgcg tgaagcgaga atcgattgat
    27121 gttgataaag acggacatca gcagcccgag ggccactacg gtcgccgtga agcggaacag
    27181 cagccaccac ggagtattgt gcagaatttg atcgtgaccc cacggatcgc ttccgattcc
    27241 caagccggtc tgcatgggac cgtcaagatg gttcaggtgc atgtggtagt gatgcgcgag
    27301 cagatccaat tgccagctgg tgcccagggc gagggcgatc agtacgcaga ccatgaacag
    27361 cggggcggcg gcgcgcaccg ccaggtcggt gactgcggtc acggttgacc gttcctcttg
    27421 ttgctgagcg gtcgtccgag agctgaatcc cagaaataac gtcagaaggc cggacagtcc
    27481 gccgaccgag gcagctacct gtggcgtcat ccagtggatc aggccgggtc cgaagatcac
    27541 gatggcgcag aggcctgacc acatgaccat tgcgatcagc acccaggaac cggtgcggcc
    27601 ccaccattcg cggtcctgtt cttcagtgaa ccggctggcg aggccgacaa aaatcgtcgc
    27661 ggtgaggaga aatatcgtca ggaccccggg gactgccagt gtggcaaacc attccgcatg
    27721 ggaggcgacg ttccattgac cgcaggtctt gatgaaggat gcccgcagaa gccatccgcc
    27781 cagcgcgccg gtgaaggcca cggcgagggt ttctaacaag agccagcggg tgaatgccct
    27841 gaatcgtttg agggcgacgg cggaaaagag ccagctgact gtgtggatca aggccccgcc
    27901 gaagaccgcg tgagcccagg tgaattgatc ggctccaccc ccgccattgc gaaaccaggc
    27961 ccatgcggtg gtgagacagg tgacggagat gagcaaggga cacagacagg cgatcagaaa
    28021 ccagcgctgg ctctccagtg tttgccacca ggtgtcgcga cggaactcac gaagggtggg
    28081 cctgcaaagg tgcaaataga tcaacgccat gaccgccagg cctatcccga tgaccagcag
    28141 cgaggcggct gaaatgggcg gcggtgatgt ctctttggca ttgagctggg cgagagcgat
    28201 gatccagcgg ggggcgagca acggcatcat gagcaaggga agcaggacca tccagttcag
    28261 atggaggttg cgcaaataga tgccgagcaa tgtccaggag tcggcggaga agaagcccaa
    28321 gtgcggactg aggtaattac tatagtttcg cagccaccgg accggcagag acgcttcctc
    28381 cgaaccggcc ttggatggtc tgttgagatc ctcgatgacg ccttttaggc cccggggatg
    28441 gcgatggatc caggcggtaa gccagctgcc gatatagccg ccgccggaca ccgtagagag
    28501 aaagtcgaat ttgtccaaca actgcaggcg tgccagggat tgcaggacgc ccagtccgaa
    28561 ggttgcgctt cgaatacctc cgccggacag gcagaggccg gcacgcttcg gatggcaggc
    28621 gtggatgtgg cggttgagtt cgtcgagata ccgcttgtcc gacgcttccg taggagctgc
    28681 ccgttccagg accttcagag ggtggtcgtc cgagaagggg ccgtgaagca gttccgtttc
    28741 ctctcccaga atgttggcaa cggtcagata ggtatctttc tcaggaccgg gagtagtcat
    28801 cgggactccg tggcgatggt ggatgaccgg ccgccagatg gcgagtgtga ttccttcacg
    28861 ggatgaaaag gcacaacaca tgcctcggtg gagaaggaca aggcggtcat tcgaagcgac
    28921 agtgcagggt cgttaatggc tggggagagg cggcggatac aagggacagt gtctgacgac
    28981 atgggtgacc gattatcgga atagatacca cccgtatctc aattgatacg acggaacagg
    29041 atgccccaac ctttccagag gtgcggttag tgtttccggt cccgctgcat cagcttgtcg
    29101 gtataggcca gaaagatcgc cgaaccgagg aaggtcatgt gaataaagat cttccacttg
    29161 atgtgttcgg ggttttcgtt ggtcacgtcc acaaaagcct tgaggaggtg aatactggaa
    29221 ataccgacca acgacgcggc cagcttgatc ttgatggtgc cggggtccac atgggtgagc
    29281 cattcagggc ggtccggatg ggtttccaga tcgagtttgc tgacgaaggt cgcgtagccg
    29341 ccgatgatga ccatggtcaa gaggttggcg accatggtga cgtcgatcag tgacagcacg
    29401 cccagcatga acagggtttc gctctcctcg cggaaatgga cgatcatgtg ccagagctcc
    29461 gtcaggaact tggcggcata gaggagttca gcgacgatca gcccgccata gaggggagct
    29521 tgaatccatc ggctcccgaa gatcaggatt tcgaagagct gctcgacgcg atgggctgct
    29581 gtagatggtg cggatggagt atgggatgga gacggatgac tcacgcgtgc acgtaccctc
    29641 cttgttgagg gcgtatccta gtgggcgcgc cggcttctgt caatcgcgag atagggagag
    29701 aggacgcgaa gcttgtatga agtcgggcgc gccggctgga tgaggagcgt cttgggggaa
    29761 cggggcaatc aagacgacgg ggtttcaggc gaggcggctt gctcaccttc caattggttc
    29821 tgcggaaccc atcgcgcgag gatcttcttc agatcggagg tgataatcgg tttgctgata
    29881 aagtcatcca tgccggcctt aagacagctt tcgcgatcgc cctccatcgc attggctgtc
    29941 atcgcgatga ccggaagatg ttcgcccggc ttttcctggg accgcagcaa tcgggtggtc
    30001 tcgaggccgt cgagatccgg catctgacag tccataaaga ccaacgggta ctgatgtcgg
    30061 cagatggcag ccagtgcctc catcccgttt cccgccaaat ccacgcggca tcccaatttt
    30121 tcgagcatct tcacggcgac cttctgattg accgggttat cgtccacgac cagcagccgt
    30181 ggcgcctcgc gagctatggc ttccgtgatg gtatgacgcg taagaaacgg agccggctgt
    30241 tccttcgcat tgtcgcggcc gaagatgaga cggatgcaat cggcgaggtg gcgttcgcgg
    30301 attggtttcg tcaggtatgc ggcggcgccg gcctcctggg cagccaggct gtctccacgt
    30361 tggcccgaag cggtgagcat gattaggtgc gtttttcgaa gagccggatc ttgtttgatc
    30421 aaccggcaga gctcgaggcc gttcatctcc ggcatgtaca tatcgataat agcgacatcg
    30481 aacggcgtcc cttcttccac ccctctccgc aggagggcca atgcagacgg gccgtcgacc
    30541 gcgctttcgt ggtgcatgtt ccacgccgac acatggtact ggaggaggct ccggttggtc
    30601 gcgttatcat cgaccaggca gacccgcagg ccggtgaggt ccaggcctga ggggatggga
    30661 ggaaccgccg gagccgcgtc cgtgtgggtg ccaaggcgga ttgtaaacca aacgcaggtt
    30721 ccctgcccgg cgaatgactg caggccgatt gttccgccca tcaactcgac gagacgtttg
    30781 caaatcgtca gcccaagacc cgttccgcca tattttctgg ccgttgagct atcggcttga
    30841 gtaaaggcct gaaacatttt ggcttgcgcc tcagggctca ggccgatgcc ggtatcgatc
    30901 acttcaaatc ggaggacgac tgagcctgga tcttcgtctg tctgtaaaac ctggatcagg
    30961 acttcaccat gctccgtaaa cttgattgcg ttgccgac
//
LOCUS       DAOQPD010000044        30857 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_656_length_30857_cov_23.579768, whole genome shotgun sequence.
ACCESSION   DAOQPD010000044 DAOQPD010000000
VERSION     DAOQPD010000044.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 30857)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 30857)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30857
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_656_length_30857_cov_23.579768"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..683)
                     /locus_tag="PK063_11305"
     CDS             complement(<1..683)
                     /locus_tag="PK063_11305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HMZ97686.1"
                     /translation="MPNQVALITGGAKGIGRAIALDLAAQHWCIAICYRTSAAAAEET
                     SAAIMARGGQALALQCDVSDPAASKQLVAQVEAQWGRIDALINGAGPYHRVNLFDETT
                     TGWREMFDGNLHPIFYLGQAVAPGMKARKHGRIINFSMANADQMVAQPEVTGHYIAKA
                     GVLILTRTLAKLLAPYGITVNAISPGFIDSGSAPAEELAGVVKRIPAGYVGSVNDTVA
                     AVRYLLSEEA"
     gene            complement(695..1447)
                     /locus_tag="PK063_11310"
     CDS             complement(695..1447)
                     /locus_tag="PK063_11310"
                     /inference="COORDINATES: protein motif:HMM:TIGR04282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04282 family arsenosugar biosynthesis
                     glycosyltransferase"
                     /protein_id="HMZ97687.1"
                     /translation="MSPQPSDRKQPASAALVIFAKAPVPGQVKTRLCPALTEDEAATL
                     HGSFVLDTLERTKAAASTFKLSFDRILACAPSSTHVFFRIMEARYGVTLFDQEGDDLG
                     ARMQHTFAQLFARGYRHICLVGTDVPSLPLTHYRDAFAALTRHDLVLGPANDGGYYLI
                     GMTRPHPKLFAHIPWSTDQVLALTQQNAAAEGLNTALLPSWNDVDTLEDLQALIEDCV
                     ADKKRPKKERIYSNRTAGTLELLAKRLRERRG"
     gene            complement(1451..2167)
                     /locus_tag="PK063_11315"
     CDS             complement(1451..2167)
                     /locus_tag="PK063_11315"
                     /inference="COORDINATES: protein motif:HMM:TIGR04283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04283 family arsenosugar biosynthesis
                     glycosyltransferase"
                     /protein_id="HMZ97688.1"
                     /translation="MTIAVIMPVLNESRCLAHILAHTQALGFDEVIIVDGGSSDDTFS
                     IAQSFAKQCDTDPLRASGSMRVLTAPRGRARQLNTGAAASACDVLLFLHADTLLPSNA
                     RRAVLTALSDAAAVGGRFNVRFDSSRLTALVVSSLMNVRSRWSGIATGDQAIFVRRAV
                     FETMGGFADIPLMEDIDFTRRLKRTGPLVSLSDEVVTAFRRWEQQGPLRTILLMWTLR
                     FLYWIGVNPHRLQHFYSMVR"
     gene            complement(2212..2619)
                     /locus_tag="PK063_11320"
     CDS             complement(2212..2619)
                     /locus_tag="PK063_11320"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97689.1"
                     /translation="MPPPSDLPDPSTRPSWPPPHRPDDESTSERQAHVFGMMIGTALM
                     FIGFLDVFLSISGGFEINVVPLLIYFSGIAVWANAVVENPTVRYSLMAGSVLISLAFF
                     HYGEVLFWHKQVVFWSTVAIVMYFMFKDPKPTA"
     gene            complement(2622..3773)
                     /locus_tag="PK063_11325"
     CDS             complement(2622..3773)
                     /locus_tag="PK063_11325"
                     /EC_number="3.5.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008829 - dCTP deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0009394 - 2'-deoxyribonucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2'-deoxycytidine 5'-triphosphate deaminase"
                     /protein_id="HMZ97690.1"
                     /translation="MKRAASSKGILPYQHITQLITRGAIKSDAPIEDRQIQPASLDLR
                     LGKKAYRLISSFLPELSAISSRLNVLDFYQSDLVMYEMDLTQGAILEKGHVYLVPLLE
                     HLELPATLRARANPKSTTGRLDVFTRVVTDLNAGFDEIRAGYTGPLYLEVVPRSFAIK
                     VRTGDCLNQIRFVRGDATVSDTALQKLHAADPLLFRNASSPKPLPQKEFRTERGLFLR
                     IDLTGSAHEEAVIGYRAKKNSHVIDLAKIGHYAALDFWEPLKRHRHDSLLLEPEEFYI
                     LASKERIRVPSGYAAEMVAYEAACGELRTHYAGFFDPGFGYGDGTMRGTQVVLEVRPH
                     DVPFLIHDGQTFFKVVYDRMLTVPSQVYGTALGSSYQRQALTLSKHFKA"
     gene            complement(3770..4903)
                     /locus_tag="PK063_11330"
     CDS             complement(3770..4903)
                     /locus_tag="PK063_11330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="KamA family radical SAM protein"
                     /protein_id="HMZ97691.1"
                     /translation="MEDWKRILAQSVVKPKDLAERLGVDPKEVEDIVGDYPMRITPTV
                     LATIKEKGDAIWKQVVPDRAEMADADAEDDPLEEDLMSPVPHLVHRYPDRVLLMVTNQ
                     CPIYCRFCTRKRLVGKPGFLKKGELDRAIAYLREHQEVRDVILSGGDPLLLPDHLLER
                     ILKSLRTIPHLELIRIGTRVPGSLPERITPKLCEIIKKYHPFYMNLHFNHPDELTPDV
                     KRACGMLADAGVPLGAQTVLLKGVNDDPEVMKRLMHQLLLARVKPYYLYQADLTKGTN
                     HFRTSVETGLKIIKSLQGHTSGMAVPHFVIDAPGGGGKIPLLPGDYLVNLDEDGAVLR
                     NYENNTYHYPQPGSPQGRELPMVGAHPSWAASGNGCDGGGEHL"
     gene            complement(5018..5263)
                     /locus_tag="PK063_11335"
     CDS             complement(5018..5263)
                     /locus_tag="PK063_11335"
                     /inference="COORDINATES: protein motif:HMM:NF024809.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase N-terminal
                     domain-containing protein"
                     /protein_id="HMZ97692.1"
                     /translation="MALTFYHVRWCPDCAVVRDRLSELNLSYEDVVVPDFRPMRKQVY
                     EVSGQYYVPVLKDGDTVLTETHDILAHLQTHYEKAQP"
     gene            complement(5333..6847)
                     /locus_tag="PK063_11340"
     CDS             complement(5333..6847)
                     /locus_tag="PK063_11340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97693.1"
                     /translation="MALAQHSREPLNSDEARRRCLAIRDALVHAGVYGPADTEQGTAT
                     AGSGVSPVRFRLSPTPFPLSSSEVMFFQHLGQDLLAFYRALNRLYQESARGTQPGWVA
                     AYLDQGKPESLVTFSRMNRFRNLIPGIIRPDVIPTADGMVITELDSVPGGIGLTACMT
                     RAYDDQLGLSPSPASPPSERSPLIAGRDGMLQGFAAMLRAQQGDREGCLAIVVSDEAK
                     EYRPEMEWMAQRLRDIGFQAFCVEPRAVRCTDEGLYLQDEHGMRTIGLLYRFFELFDL
                     KNIPKSELMMYAAKKGQVAVTPPYKPALEEKLAFGLFHHPELEPFWKETLTAETRTNL
                     GQLFPRTWILDPQPVPPTAVIPHLLISGRAVSDFRRLAHTTQKERQLVVKPSGFSELA
                     WGSRGVSIGHDLPQVEWAAALEQALQSFSTTPYVLQEFHKGRLFEASYWDERSDTVVP
                     MSGRVRLSPYYFVAGDKAELGGILATLCPANKKIIHGMVDAIMAPCAIAPGVAA"
     gene            7067..8575
                     /locus_tag="PK063_11345"
     CDS             7067..8575
                     /locus_tag="PK063_11345"
                     /inference="COORDINATES: protein motif:HMM:NF021445.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerol lysyltransferase
                     domain-containing protein"
                     /protein_id="HMZ97694.1"
                     /translation="MTSPLVPVSPANPTRPVGQSLLQIVPSTTCLHCDVCCRFPEVDS
                     FLRPFFTGDEIRAAVAAGLTPELFPTTEGTQIDLVPNPAGEGYVCPAFDSETSHCRIY
                     EVRPLDCRLYPFALMWDAERTHVLLGWDTKCPYMRDAPSSLVDQAVDGVAQWVEADER
                     VDTLARYPRLIGRYQDDVIPLRTLARVTERVQRAKPQIRRQALTIQDRGRIEAALTVT
                     AGFQESPLAAASFAYHYIWKHRLTYTWAELQGHLCLFAESPDGIFLVLPPLGSGPIDQ
                     PTAEAFRLMRAWNGDSSVTRMENVPESFVPALRASGYETGEKEPDYLYAAADLVDLAG
                     EAYRSPRAACNRFVREHGGVLEPYDCRDQTACVSLFREWREQKLRSGSDEWANALLED
                     AVGAHETALSAHSELGLTGAVVRVGGRIRAYTIGLWLNQSVFCVLLEVADRDIVGAGA
                     FVFREFCRQAHAKGACWINTMDDSGLPSLAKAKRWYHPARLLPNYVVTEFRR"
     gene            8572..11673
                     /locus_tag="PK063_11350"
     CDS             8572..11673
                     /locus_tag="PK063_11350"
                     /inference="COORDINATES: protein motif:HMM:NF024583.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ97695.1"
                     /translation="MTASPLPGFPRRSYPWLPVLIVGVTIVALVIGVVMLRSIEVRMV
                     EATGENLTLASAEIADKLDRLLFERHADVRMMARAFTDRSADKKYINEYLQWMKETYA
                     PVYLWLGVTDPHGRMIAATDSSIIGQDYGRSGWFDRVRQTHTVQVDEVEIHESNHKIE
                     SVAFTAPILSVSGQFLGAVTTRIGLPMLEDVLIETVREIQQTDGAAGPFEYQFLTKGG
                     LVFVDSSSSNIDRVNLRELNLPSVLRSSSGKAGYVEEIHVRRHVPVVTGYSQTKGYSD
                     YSGLQWTILLRIDRDVILLPIRAMMWKLGIAGVVVWLPMVGLLLWATGRLREQHRQAQ
                     QESEWARAAEAALLQSQERNRVIVDTALDAVISMDAGGIITDWNAQAVNIFGWEREEA
                     LGRRVSETVIPVRDRDGHERGLRHFLETGQGALLNRRIEMMGSHRDGHEFPVEITISP
                     ARLGDAYIFSAFIRDITARKRTERQLASQYAVTRVLAESRTLEEAGPKILQAICESLE
                     WELGIFWRLDRQGSVLRCLDVWQSPGLNAEEFVLDTWRHTFALGKGLPGRIWQAGEPT
                     WIKDVVQEANFPRGGAASRVGLHGAFGFPVRVGTEVEGVIELFRREIKQPDEQLLKMV
                     ADVGLKIGQFGERARAEDALRRTEAQLQQSQKMEAVGRLAGGVAHDFNNMLTVIRGYS
                     ELVLSRLSPTDGFRKELEEVKKAADRASGLTGQLLAFSRRQFIAPKVLDLNSVIHNME
                     GMLRRLLGEDIVELCTVLDPGLGQLKADPGQVEQVIMNLAVNARDAMPDGGRLTVETA
                     NVQFGQRRNRPPMGAEPGSYIALIVRDTGHGMDEDTQSHVFEPFFTTKEKGKGTGLGL
                     STVYGIVKQSGGFIEVESKPGRGATFKIFFPRVEAVSEETESVAVGGDSVRGRETVLL
                     VEDEPGVRRLVNETLRLHGYTVLEARHGIEALLTGAKHAGPIHLLLTDVVMPQMSGPE
                     VAEKLATVRPEVKVLYMSGYPDHPAFSKGGIDTEHSFLQKPFTPTTLAQKVREVLDGS
                     KVS"
     gene            11768..12607
                     /locus_tag="PK063_11355"
     CDS             11768..12607
                     /locus_tag="PK063_11355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CbbQ/NirQ/NorQ/GpvN family protein"
                     /protein_id="HMZ97696.1"
                     /translation="MSEGRAATAPKGQAQDIDHYRIACEPFYADVRGEVGLFTIAAQS
                     RMPVMLKGPTGCGKTRFVQHMAYRLGRPLITVACHEDLTASDLVGRYLLKGQETVWMD
                     GPLTLGVKQGAIVYLDEIVEARKDTTVIIHPLSDDRRLLPIEKKGQVIEAVDEFMLVI
                     SYNPGYQSILKDLKQSTKQRFMAIEFDYPLPDIECRVVAHEAGVSPEIAQRLVKIAEK
                     VRNLKNHGLEEGVSTRLLIYAATLIKQGVPADRACDVAIARPITDDPDMLRSIIEVVK
                     AIF"
     gene            12653..12988
                     /locus_tag="PK063_11360"
     CDS             12653..12988
                     /locus_tag="PK063_11360"
                     /inference="COORDINATES: protein motif:HMM:NF014633.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF167 domain-containing protein"
                     /protein_id="HMZ97697.1"
                     /translation="MTTHNSGRESKSSAAAQVVRTTPEGAVISVHVQPKASRTQCAGL
                     HGDAVKIRVAAPPADGAANEELCRFLARTCGLPVSGVEILSGTSSRQKRILLRGRSAE
                     QVRAQLQLE"
     gene            13044..13529
                     /locus_tag="PK063_11365"
     CDS             13044..13529
                     /locus_tag="PK063_11365"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97698.1"
                     /translation="MHGEPGVELWPRSSVLRKIRSIIFRWSLSLIVVVVSGCAGPEPI
                     FKSTTYLQLHGQQQAQDEAAVCAVKAERAGLQHGTNRSGNAGAGAALGVIGGAAVGAS
                     AGLVGGPTGIAIGAAAGGAVGGILGLFAGTYKPLHPRQDYAAFVERCLKEKGYETEGW
                     Q"
     gene            complement(13568..14734)
                     /locus_tag="PK063_11370"
     CDS             complement(13568..14734)
                     /locus_tag="PK063_11370"
                     /inference="COORDINATES: protein motif:HMM:NF016289.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M28 family peptidase"
                     /protein_id="HMZ97699.1"
                     /translation="MAGCLHTMEALDPRALPVTTAPAQRLQSYVSFLASPALAGRQPG
                     TPGNRQAAQYIEEQFRLVGLQPLASLGGYRQTISDRMGDNVIGVIPPIDHTARTRWIV
                     IGAHYDHLGYPFLGADDNASSIAILIETARNLTGLSRHGIMFVAFNGEELPYFGTAEM
                     GSQFLFHHLPPEVGAAENLQAAIIMDLMGGVHWAPLKDAIFATGAEKSPALYRRVTET
                     RVSPLTIYRGGIHLVEEIPDHGHKAFSDYDVFRNQKVPFLFLSAARSPRYHTAGDVAS
                     TLHYERMAATVEWLRQLLALMSQDEAPYAFDAHRVEFADEVASFTSLVEQALHEETRI
                     PGTSRWSLRKLEQDLEWLREVRGSAPTPQQLERLERISIRVQCLMADYSGCFTF"
     gene            complement(14812..15258)
                     /locus_tag="PK063_11375"
     CDS             complement(14812..15258)
                     /locus_tag="PK063_11375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016730 - oxidoreductase activity, acting
                     on iron-sulfur proteins as donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-thioredoxin reductase catalytic
                     domain-containing protein"
                     /protein_id="HMZ97700.1"
                     /translation="MAEPSKESLEKMWKYVKGFAEKSGTAMHPNPAVTNAVVLGLAAH
                     VDELGKPLCPCNFYPDKQAEAKLRRWMCACDEMQIYKYCHCLLFVNEEGLPITEYLPE
                     DHEGRQCYGLVPDPTPGKGRALRHKALPMAPKVPESPATPDSSAQS"
     gene            15390..18425
                     /locus_tag="PK063_11380"
     CDS             15390..18425
                     /locus_tag="PK063_11380"
                     /inference="COORDINATES: protein motif:HMM:NF012321.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HMZ97701.1"
                     /translation="MAPGHSFPQLIERLADQLGPASATTMVDAIVASATRPDAPAGVW
                     LLLEELTDAAPKAARGAIEALLELQRRGLLAEVLPWLDLGVAIAADSGALALRFFKES
                     PLLLGLLDPPQRAVVLAAGLELADRQANVAVEFIRVAPEVVPVLPPADWPTWMELACE
                     LSETDFALAVEYIRQIPAIARVLSLDTVRAWMQFGMTLIVDNSLGKPDYLGALEFFRT
                     SPGILADIPDQISRHQVIRVGAQIAERSPEMGIALLSEAPSILRGLPTDEWRRQVLQY
                     GLILAERDAETALAYMRRCPELVALIGSGEGAQQKFQSWFASGMDVLEYSVEGGRAYF
                     GMESEKALGALSQAMSGVPLRQIARRVKLFAQALCGRDLRIYDLPDSLESAQPMPRAT
                     VSDDGRSIGLPSLVRRHSTYEENVRLYMVMAAHEAGHLEFGTFDLPLARLEDVSKELT
                     QRYGRPALREVRTLGDMFARYPQPGLIRDLWALVEDARVEYLLRREYPGLSRDLAVIA
                     KDAVQVRSLAHGMTVRELVVDQLLLLSTVEAGSLPLPDALKREIMHLWSLCQTIFHPQ
                     ATAEEAVRLADRLYVSMDELLAIRREAIPSPDEAESPEQSIPAPKASEDLSDTYRPMD
                     NWDYRGAMDPNLVRDRTESTPEQSPASGQGDSEGGAGLAGDSGGSSGAGTARSQQMSQ
                     EMLVPGRRQPSLVEEMLAVEGEGARPQDDQTETVKAVRYREWDAAIQDYRMNWCRVVE
                     REAVEGSSDFVEGTLAAQRGPVALLRRYFESLRPPGLRRVPGQVDGEDLDMDAVIGRL
                     ADIQAGIEPSERIYVRREKREREVAAAFLVDLSGSTSRQVERGRRIIDIEKQGLVLLC
                     EALSAIGDQFAVYGYSGQGRHLVDFVVVKDFDQLVTGRAGAKLGGMVPLQQNRDGAAI
                     RHATTKLLARQAKTRLLVMISDGRPLDDGYKDEYSLEDTRMALREARASGIEPVCITI
                     DKQADPYLRRMYGDVRYVVIDRVEGLPEKLPRIYHRLTA"
     gene            18469..18879
                     /locus_tag="PK063_11385"
     CDS             18469..18879
                     /locus_tag="PK063_11385"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97702.1"
                     /translation="MIEQSPRPTVPPWLYKLFTGHQYPYVRRQAKFANRDFKPGEERP
                     EPTREAIDAKFWEIYPRCTAKILQEVKAGMIVVFHELGEYPPGGYQDLVDAPEEFLAA
                     KYGKKKIKVNFYDGDNFVCTINFKVGGWTGHEPA"
     gene            18952..19893
                     /gene="mdh"
                     /locus_tag="PK063_11390"
     CDS             18952..19893
                     /gene="mdh"
                     /locus_tag="PK063_11390"
                     /EC_number="1.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HMZ97703.1"
                     /translation="MGRPKITVVGAGNVGGTAAQRLAEKNAYDVVLVDIVPGIPQGKA
                     LDITQAGPVCGYSTRVVGTNGYDETAGSSIAVITSGIPRKPGMSRDELLGTNAKIVKT
                     VVQELVSRSPNIILILVTNPLDAMVHVARKVSGLPKSRVLGMAGVLDTARLRSFVAEE
                     LDVPGTDVQAMVLGGHGDTMVPLVRQTTVAGKPITDRLSSERLAALIKRTQDGGAEIV
                     GLLKTGSAFYAPSASVVDMVEAIMKDQKRVVPCAMLCEGEYGLKDVIVGVPVRLGRGG
                     GESIVEYDLTVEERTALQASSDAVRDLCGVVDRLLTA"
     gene            19997..20584
                     /locus_tag="PK063_11395"
     CDS             19997..20584
                     /locus_tag="PK063_11395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014450158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urate hydroxylase PuuD"
                     /protein_id="HMZ97704.1"
                     /translation="MKFLEDPYQTLGAGVALAVGLIVVYLGMAGVGAGEADWFGLVVR
                     WVHFLAGITWIGLLYFFNLINAGFLKSLDGPTKNIVIPKLMPAALNWFRHGATVTVLA
                     GIVLYGYLYSKGGTGALALGIGGLLGIIMMGNVHGIIWPNQKKVIAAVAAAAQGTPAP
                     PEMAQWGKTALYASRINFLLSIPMLFFMGAGSHLK"
     gene            20838..22139
                     /gene="nuoF"
                     /locus_tag="PK063_11400"
     CDS             20838..22139
                     /gene="nuoF"
                     /locus_tag="PK063_11400"
                     /inference="COORDINATES: protein motif:HMM:NF010120.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HMZ97705.1"
                     /translation="MTLPQPRVLQKLDGAPWEIDPYLKTGGYDAWRKCLKELTPADVV
                     GEIKKAGLRGRGGAGFPTGIKWDKVLNHRVPERYFVCNAGEHEPGTFKDRHLLKHIPH
                     QLIEGCLIASRTVNAKASYIYVNHEYEEEEANLRKAIAQARERGLLGKNILGTGVDLD
                     LEVFSGHGSYVAGEETAMLESMQGRPAMPRQKPPFYPTDFGLYGKPTLVNNVETLCNI
                     PQILKNGAAWFTQVGTEKCPGTMLFSLSGSINRPGVYEMPMGVTIRDLIETCGGGVPN
                     GRKIKAVFPGGPAFSMVTADQLDLPMDFDSLKKAGTGLGSAGTIVIDDATCMVAATLK
                     YSNFFKGESCGQCPPCRMGTINLATLVEKIERGEGSQKDLDSLLQLCGFVKGTGYCTL
                     ITGAAVLVQSSLRLFQHEFEEHIRMHRCPFQSAQTGVGAKA"
     gene            22152..22508
                     /locus_tag="PK063_11405"
     CDS             22152..22508
                     /locus_tag="PK063_11405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="HMZ97706.1"
                     /translation="MPRVSFLHPEGRSGEVESNLTLLEAAKALGFGLNHDCGGNASCT
                     TCRVEVQMGGENLSEIDFDEQDLLDREALSEPWHRLGCQARVLGDVVVRVPETKWVQP
                     TSASSSQFGKKGAGLP"
     gene            22567..22893
                     /gene="erpA"
                     /locus_tag="PK063_11410"
                     /pseudo
     CDS             22567..22893
                     /gene="erpA"
                     /locus_tag="PK063_11410"
                     /inference="COORDINATES: protein motif:HMM:NF010147.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster insertion protein ErpA"
     gene            23029..23478
                     /locus_tag="PK063_11415"
     CDS             23029..23478
                     /locus_tag="PK063_11415"
                     /inference="COORDINATES: protein motif:HMM:NF013411.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase"
                     /protein_id="HMZ97707.1"
                     /translation="MSEATITRRYRFCAAHRLHTDQLSSEENWTTFGKCNNPNGHGHN
                     YVVFVSVRGDMDSVTHQVVDLSKLDEVVQRIVVRRFDHQDLNKDPEFTTQTTTGENLV
                     LLIWNLLVNEVPGGRLVKVGVIETRDNYFEYSGSAKQVRREDGVRHG"
     gene            23471..24106
                     /gene="folE"
                     /locus_tag="PK063_11420"
     CDS             23471..24106
                     /gene="folE"
                     /locus_tag="PK063_11420"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0042559 - pteridine-containing compound
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HMZ97708.1"
                     /translation="MAKVVSGSRARRSRTTATPTADDPIEGLMTKLLLELGEEPGRNG
                     LLNTPKRVAKAMRFMTQGYRQDIDHLLNGALFPIEYDEMVIVKDIDFFSMCEHHLLPF
                     FGKCHVGYLPNKKVVGLSKIPRVVDAFSRRLQVQERLTVQIAETLKKKLNAHGVAVVM
                     EARHLCMMMRGVEKQNTVAVSSSMLGVFRTQQQTREEFLKLIRGSSVKDGG"
     gene            complement(24103..24912)
                     /locus_tag="PK063_11425"
     CDS             complement(24103..24912)
                     /locus_tag="PK063_11425"
                     /inference="COORDINATES: protein motif:HMM:NF024109.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HMZ97709.1"
                     /translation="MFFQTQDIRLAYDDRGSGVPLVFLHAFPLNRSMWAPQVAALSTQ
                     FRTIALDFRGHGESDAPLWSFSLEQYADDVAALLDHLNIPQAVLVGLSMGGYVSLAFS
                     KKCGDRLCALVLADTRAQEDSPEGKRGRFHLAQTAYTQGTEAVANTMLPKLLGATSLK
                     SKPELVEQIRRTIEHTPVSGILVDLMAMAERSDSVAHLTAISCPTLVVIGDEDHTTSL
                     VDAQIMASHIPNARLAVIPAAGHLSNCEQPELFNDLLRGFVEGVRANGRRS"
     gene            25059..26378
                     /locus_tag="PK063_11430"
     CDS             25059..26378
                     /locus_tag="PK063_11430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HMZ97710.1"
                     /translation="MPAHDSTGDLFASSQPAPRITPSGKVPLAERLRPRSFDDLVGQD
                     DVVGPGRPLRSAIEQDRLSSVIFWGPPGCGKTTLAGLVAQYTKSQFVPFSAVTGGIPE
                     LREIIKAAEQRRTRGMATILFVDEIHRFNKAQQDAFLPHVERGTVVLIGATTENPSFE
                     LIAPLLSRSLVIVLQPLTTEALGSILDRAVADTDRGLGSLRLTIQPAARDRLIAFGNG
                     DARSLLTTLEFVAGQAPVGMDGRRIIDESVLEAALLKKALRYDKGGEEHYNLISAYIK
                     SLRDSDPDGALYWLARMLEGGENPRFIARRMVIFASEDIGNAEPQALVVANAVAQAVE
                     FVGLPEAQITLAHGTTYLASRPKDNASYVGLQEAIRDARQHGNLGVPLHLRNAVTSLM
                     KEIGYGQGYRYVHNDPAAKSEQGHLPEPLKGKRYYRPRTAQDHEERG"
     gene            26420..26797
                     /locus_tag="PK063_11435"
     CDS             26420..26797
                     /locus_tag="PK063_11435"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ97711.1"
                     /translation="MARQTNSTESVSERRKYVRATLVGSALVSPQNGAKGFTAVLNNV
                     NKIGAGLHSKETLPIGAKITVSLAFLDPDRVEQQEKLSATVAWAKPWEKGMLLGVVWD
                     DLVTKEKNRWLYYYLEETLKSTD"
     gene            complement(26794..28635)
                     /locus_tag="PK063_11440"
     CDS             complement(26794..28635)
                     /locus_tag="PK063_11440"
                     /inference="COORDINATES: protein motif:HMM:NF012235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HMZ97712.1"
                     /translation="MLQLESVHKQYSTKVLLEGATAHLRPGARVGLVGPNGAGKTTLF
                     RMILGEESPDKGTIRKRPRLRVGYLPQELETIVGKTVLDAAHRDIYPEHEAERILSGL
                     GFTEADFSRPIENLSGGYRMRVALAHLLLSNPDVLMLDEPTNHLDKPTQRWFERFLLE
                     SNLTLLVISHDTKFLDGIATHIWELRDRTLQEYRGNYTKFQELRAARDAQIEAAANRQ
                     SKEVARVQSFIDRFRYQANKAKQVQSRIKQLDKVKLIERQRDTKRVRFKFPLPAASGR
                     HVLELKGVAKSYGEKVIYRSLNFAVERGQRIALVGENGAGKSTLLKMLAGVLPFEKGS
                     RHVGHGVTLHYFAQHQAESLNQDHTILESLAEVSAQAETNFLRGIAGAFLFSGDDQKK
                     PIKALSGGERNRVALARMLVEPANTLLLDEPTNHLDPASVDMLTDAMTDFPGTIVFIS
                     HDPTFLARVATMIVEVDEGQAKTYLGDYEYFLWKKAQEFESIKESSAELAAAQNDKSS
                     GPTKAMASQVQQKSSGGERRDLNKTQARLEKQVSRAESEIASTESKVKARELELADPA
                     LYKELGRWSELQQEQETWKKELERLTARWESLSEELQGVREKLTALG"
     gene            complement(28795..28870)
                     /locus_tag="PK063_11445"
     tRNA            complement(28795..28870)
                     /locus_tag="PK063_11445"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(28835..28837),aa:Ala,seq:ggc)
     gene            29344..30666
                     /locus_tag="PK063_11450"
     CDS             29344..30666
                     /locus_tag="PK063_11450"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HMZ97713.1"
                     /translation="MANLVIIGSQWGDEGKGKIVDILAKDADMVVRYQGGSNAGHTVI
                     NKRDTFIFHLIPSGILYRGTRCLIGNGVVVDPGALIEEMDHLQGQGVKIGKNFAVSDR
                     AHLILPYHKAIDKASEQSKGVRRIGTTGRGIGPSYGDKMARIGIRMGDLLNPPLFKQK
                     LEENLVDINWLLEQLHKVDCFELEKVYQQYMAYADRLKSYILDTTMVVNKAVDAGKTV
                     LFEGAQGTHLDVDFGTYPYVTSSSSSAGGACTGTGVGPTKIEAVMGITKAYTTRVGSG
                     PFPTELTDEVGGWLQERGKEFGATTGRARRCGWFDSVVVRHATRVNGLSSLAVTKLDV
                     LDGRNELKICTGYRVNGKLHRDMPSDLLALTNCEPVYERIRGWSAPTTGVTTYKKLPV
                     EAKRYLTRIEELAECRIDMISTGSRRDETIILNNPLKAGRRKRAPRSR"
     gene            30782..30857
                     /locus_tag="PK063_11455"
     tRNA            30782..30857
                     /locus_tag="PK063_11455"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30815..30817,aa:Lys,seq:ttt)
BASE COUNT         6403 a         8343 c         9565 g         6546 t
ORIGIN      
        1 gcctcttcac tcagcaagta tctcaccgcg gcgactgtat cgttgacgct tcccacatat
       61 cccgctggga tccgtttgac cactcctgcc agttcttccg caggggcact gcctgaatcg
      121 ataaagccgg gcgaaatcgc gttgaccgtg atgccatagg gggcgagcag cttcgccagt
      181 gtgcgagtca ggatcaacac tccggctttg gcgatataat gacccgtcac ttccggctgg
      241 gccaccattt ggtcggcgtt ggccatgctg aaattgatga tccgcccatg tttcctggct
      301 ttcatgcccg gcgcgactgc ttgcccgaga tagaaaatcg gatgaagatt tccatcgaac
      361 atctcgcgcc agcccgttgt cgtttcgtcg aagaggttta cgcgatggta agggcctgct
      421 ccattgatca acgcgtcgat ccgtccccac tgcgcttcga cctgtgcgac caactgcttg
      481 gaggccgccg gatcggacac gtcgcattgc agggcaaggg cttggccgcc acgtgccatg
      541 atggccgcgc tggtctcttc tgcggctgcg gcactcgtgc ggtagcaaat agcgatgcac
      601 caatgttgtg cggcaaggtc gagggcgatg gcgcggccga tccccttggc tccgcccgtg
      661 atgagtgcaa cctggttcgg cataccgtct ccttctagcc ccgccgttcg cgcaggcgct
      721 tggcgagcaa ctccagtgtt cccgccgttc tgtttgaata gatgcgttcc ttcttcggac
      781 gtttcttatc cgcgacgcag tcctcgatca aggcttggag atcctccagt gtgtccacat
      841 cgttccagga gggcagaagt gcggtgttca ggccttctgc ggcagcgttc tgctgagtga
      901 gtgccaggac ctgatctgtc gaccagggaa tatgcgcaaa cagtttcggg tgcggcctgg
      961 tcatgccgat caggtagtac ccgccgtcgt tggccggtcc caggacgaga tcatgccggg
     1021 tcagtgcggc aaaggcatcg cgatagtgtg taagcggcag cgaggggaca tcagttccca
     1081 ccaggcagat gtgtcggtac ccgcgggcga acagctgagc gaacgtgtgt tgcatgcgag
     1141 cgccgaggtc gtcgccttcc tgatcgaaga gtgtcacccc gtagcgtgct tccatgatgc
     1201 ggaaaaacac gtgcgtgctc gagggcgcgc aggccagaat acgatcgaac gacagcttga
     1261 aggtgctggc cgcggccttg gtgcgttcga gcgtgtcgag gacaaagctg ccgtgaagcg
     1321 tggcggcttc gtcttcggtc aaggccggac aaagtctggt tttcacctgt cccgggaccg
     1381 gcgctttggc gaagatcacc agggcggcgg acgcaggctg tttacggtcc gagggttgag
     1441 ggctcatcac tcatctcacc atgctgtaaa aatgttgaag tcgatgcggg ttgaccccga
     1501 tccagtacag gaagcgaagg gtccacatca acagaattgt gcgaagagga ccctgttgtt
     1561 cccatcgacg gaaggcggtg acgacctcat ccgacaagga gaccagcggc ccggttcgtt
     1621 tgagccgccg cgtgaagtcg atgtcttcca tcaggggaat gtcggcgaat cctcccatcg
     1681 tctcaaaaac ggcgcgccgc acaaagatcg cttggtcgcc ggtggcgatt ccgctccagc
     1741 gcgagcgcac gttcatcaga ctgctgacga ccagggctgt cagtcgagag gagtcaaacc
     1801 ggacattgaa gcggccgccg acggcggctg catctgagag tgcggtcaag acggcccgcc
     1861 gcgcgttcga tgggaggagg gtgtcagcat gcaaaaagag caggacatca cacgcgctcg
     1921 cagccgcgcc ggtattgagc tgcctcgcac gcccgcgtgg ggcagtcaat acacgcatcg
     1981 atccgctcgc gcgtaaggga tctgtatcac attgcttggc gaatgactgc gcaatggaga
     2041 aggtgtcgtc ggaactcccg ccgtcgacga tgatcacctc gtcaaaccct aatgcctgag
     2101 tatgggcgag gatgtgagcg aggcaacggg attcgttcag caccggcatg atgacggcga
     2161 tggtcatcgg agccggagag cacccgtcgt atgagggccg ctcgcggcca tttacgcggt
     2221 cggtttgggg tccttgaaca tgaagtacat cacgatggcg acggtggacc agaagaccac
     2281 ctgcttatgc cagaacagga cctcgccgta atgaaagaag gccagactga tcaggacgga
     2341 tccggccatc aaggaatagc ggacggtcgg attttccacg accgcgttag cccagacggc
     2401 gatgccgctg aagtaaatca agagcgggac gacgttaatt tcaaatccac cgctgatgga
     2461 gagaaacacg tccaaaaaac cgatgaacat caacgccgtg ccgatcatca tcccgaagac
     2521 gtgcgcctgc cgttcggagg tgctttcatc gtccgggcga tgtggaggcg gccaggacgg
     2581 acgggtagag ggatctggga ggtcgctggg aggtggcatg ttcaggcctt aaaatgtttg
     2641 ctgagggtga gggcttgtcg ttggtatgac gagccgagcg ctgtcccata cacttgtgat
     2701 gggaccgtca gcattcgatc atacactact ttgaagaagg tttgcccgtc atgaatcagg
     2761 aatggcacat cgtgcgggcg aacttccagc acgacctgcg tgccgcgcat cgtcccatcg
     2821 ccatacccga aaccggggtc gaagaagccc gcatagtgcg tgcgtagctc accgcaggcc
     2881 gcttcgtacg cgaccatttc ggcggcatac ccggacggga cgcggattcg ttccttggag
     2941 gccaggatat aaaactcttc cggctctaac agaaggctgt cgtgccggtg cctcttgagc
     3001 ggttcccaga aatccaaggc cgcatagtga ccgatcttcg ccagatcaat gacatgactg
     3061 ttcttctttg cccgatagcc gatgacggcc tcctcgtgag cgctcccggt gaggtcgatc
     3121 cgcaaaaaca gtccgcgctc cgtccggaac tctttctgag ggagcggttt cggcgaggac
     3181 gcattgcgga agagcagggg gtcggccgca tgcaattttt ggagagcggt atccgaaacc
     3241 gttgcatctc cgcgtacgaa ccggatttga ttgaggcaat caccggtgcg caccttaatg
     3301 gcaaatgacc ggggaaccac ttccagatac aggggccctg tgtagccggc ccggatctca
     3361 tcaaacccgg cgttcaagtc ggttacgaca cgggtgaaca cgtccaggcg ccctgtcgtg
     3421 cttttggggt tggcacgggc gcggagcgtg gccggcagtt cgaggtgctc caggagcggc
     3481 accagataga catggccctt ctccagaatg gcgccttgcg tcagatccat ctcatacatg
     3541 acgagatcag actgataaaa gtcgagcaca ttgagacggc tgctgatggc cgataactcg
     3601 ggcaagaagc tgctgatcag ccgataggct tttttgccca gccgcaagtc cagactggcc
     3661 ggctggatct gccggtcttc gatcggggcg tccgacttga tggcgccacg ggtgatcagt
     3721 tgggtaatgt gctggtaagg tagaatcccc ttcgaggacg cggcccgttt cacaggtgct
     3781 caccccctcc gtcacacccg ttgccggatg cggcccagga agggtgggcg ccaaccatcg
     3841 gcaactcgcg gccttgaggg gagccgggct gaggatagtg atacgtattg ttttcgtagt
     3901 ttctcaacac cgcgccgtct tcatccagat tgaccagata gtctcccggg agtagcggaa
     3961 ttttcccgcc gccgccgggg gcatcgatca caaagtgagg cactgccatc ccgctggtat
     4021 gaccttgcaa cgacttgatg atcttgagcc ctgtttccac cgaggtccgg aaatgattcg
     4081 tgcctttggt caaatccgct tgatacaggt aatagggttt gacgcgcgcg agcagtagct
     4141 ggtgcatgag ccgtttcatg acctcggggt catcgttaac ccccttcagt aacacagtct
     4201 gtgctcccag gggaaccccg gcgtccgcca gcatgccgca cgcacgcttc acgtccggcg
     4261 tcagttcatc cggatggttg aagtgcaggt tcatatagaa gggatgatat ttcttgatga
     4321 tctcgcagag tttcggggta attcgctcag gcaggctgcc cggtacacgc gtcccgatgc
     4381 ggatcaattc cagatgcgga atcgtgcgga gcgatttgag gattcgttcc aagaggtgat
     4441 ccggcagtag caatggatca ccaccggaca ggatgacatc ccgtacctcc tgatgttccc
     4501 gcagatacgc gatggccctg tcgagctccc cctttttgag gaagcccggt ttgccgacca
     4561 gccgttttcg ggtacaaaac cggcagtaaa ttggacactg attggtgacc atcaacagca
     4621 cacggtctgg ataccggtgg accagatggg gcaccgggct catcaggtct tcttcgagcg
     4681 gatcatcctc cgcatcggcg tcggccattt cagcgcgatc cggcacgacc tgcttccaga
     4741 tcgcgtcccc cttctccttg atggtggcca acacggtcgg cgtaatgcgc atgggatagt
     4801 cgcccacgat gtcttcgact tctttggggt cgacaccgag ccgctcggcc aggtcttttg
     4861 gcttcaccac gctttgagcc aggatgcgtt tccaatcctc cacgtttcta tcctttcgct
     4921 gatgccgttc caaccggccg ggccgtattg gccggagcct tgtccgggca tctcgtctga
     4981 tccgtgatcc tcaacggtcg ccctaatagc gacctcctca cggttgcgcc ttttcgtagt
     5041 gtgtctgcag gtgtgccaga atgtcgtggg tttctgtgag caccgtgtct ccgtctttca
     5101 agacggggac gtagtactgg ccggatactt cgtagacttg tttgcgcatt ggccggaagt
     5161 ccggcacgac cacgtcttcg taggacaggt tcaattcact gagacgatcc cgaacgaccg
     5221 cgcaatcggg acaccatcga acatgataga aggtcagagc catgagttcc tattggggaa
     5281 aagagtgaat agccgtccac tgaacagatt gtattcccgt cctcacctca ccctaggcag
     5341 ccacgcctgg cgcgatcgca cagggcgcca tgattgcgtc gaccatgcca tgaatgatct
     5401 tcttattggc aggacagagt gttgccagga ttccccccag ctcggccttg tcgccggcaa
     5461 caaaataata gggggataag cgaacccgcc cggacatcgg caccacggtg tcgcttcgtt
     5521 catcccagta ggacgcttcg aacaaacggc ctttatggaa ttcttgaagc acgtaaggcg
     5581 tcgtggaaaa ggactgaagc gcctgctcca aggccgcagc ccattcgact tgcggcaggt
     5641 catgcccgat ggagacgcca cggctgcccc aggcgagttc ggagaatcct gagggcttga
     5701 ccaccagctg ccgttctttt tgagtcgtgt gggccaggcg gcgaaaatcc gatacggccc
     5761 gcccgctgat gaggagatgt gggatgacgg ctgtcggagg tacgggttgc gggtcgagaa
     5821 tccaggtgcg agggaataat tgtcccaagt tcgttctcgt ctcggcggtc aacgtctcct
     5881 tccagaatgg ctccagttca gggtgatgga atagcccgaa ggcgagcttt tcctccaagg
     5941 ccggcttgta cggcggcgtg acggcgacct gtcccttctt ggcagcatac atcatgagct
     6001 cggatttcgg gatgttcttc aagtcgaaga gctcaaaaaa gcggtagagc aatccgatgg
     6061 tccgcatgcc gtgctcatcc tggagataca gcccttcatc ggtacaacga accgctcgcg
     6121 gttcgacaca aaacgcctgg aaaccgatat cgcgcaggcg ctgggccatc cattccatct
     6181 ccgggcggta ttctttcgcc tcgtcggaga caacgatcgc caggcaccct tcccggtcgc
     6241 cctgctgagc gcgcagcata gcggcaaacc cctgcaacat gccgtcacga ccggcaatca
     6301 gcggagaccg ttcggatggt ggagatgcag gcgaagggct gaggccgagc tgatcatcat
     6361 aggcgcgtgt catgcacgcc gtcaggccta ttccgccggg cacggagtcg agctccgtga
     6421 tcaccatgcc atcggccgtc gggatgacat ccggccgaat gatgccgggt atgaggttac
     6481 ggaaccggtt catccggctg aacgtgacga gggattccgg tttgccctga tcgagatagg
     6541 ccgcaaccca cccgggctgg gttccgcggg cactttcttg ataaaggcgg tttaatgccc
     6601 ggtaaaacgc cagaagatcc tgccctaagt gctgaaaaaa catgacttcc gacgaggaaa
     6661 gcggaaaggg tgtcggagaa aggcggaatc gtaccggcga aactccggaa ccggccgtgg
     6721 ctgtgccctg ttccgtgtcg gccgggccat agacgccggc gtgaacgagc gcatcacgga
     6781 ttgcgagaca acgtcggcgg gcttcgtcgg agttcaacgg ctcacgtgaa tgttgtgcca
     6841 gtgccaatgc aatatcctcg atgctcgcag cgcagtcgca tgcttcgcag tcgcggtcgg
     6901 attcgaggtg gagcaaatcg taccatggcc tcttgcactg gtacaagtcg gcgaggcgcc
     6961 tgagaggctc gtcggcagct ggtggatctg ctccacagcc cttggacggc aaacatgtgg
     7021 aacagtagga ccacgtgcag gttagtgata caatgcgcgc cagctcatga cgagtccact
     7081 cgttccagtc tccccagcga atcccacacg gcccgtaggg cagtctctcc tgcagatcgt
     7141 gcccagtacg acctgtcttc attgcgacgt ctgttgccgg tttcccgagg tagacagctt
     7201 cttgcgtccc ttcttcaccg gcgatgagat ccgtgcagca gtggcggccg gcctgacacc
     7261 ggaactgttc ccgactaccg aaggcacgca aatcgatctg gtcccgaacc cggctggcga
     7321 aggatatgtc tgcccggcct ttgacagtga gacctcgcac tgccggatct atgaggtccg
     7381 ccccctggac tgccggctct atccgtttgc gttgatgtgg gatgccgagc gcacccacgt
     7441 cctcctcggg tgggatacga agtgtcccta tatgcgcgac gctccctcgt cgctggttga
     7501 ccaggcagtc gacggggtgg cgcaatgggt tgaagcggat gagcgggtgg acacgcttgc
     7561 gcgatacccc aggctcatcg gacggtatca ggacgatgtt atccctttgc gcaccttggc
     7621 acgggtgacc gaacgtgtgc agcgagcaaa gccgcagata cgtcggcagg ccctgaccat
     7681 tcaggatcga ggtcgaatag aagccgcact gaccgtcacc gccggttttc aggagagccc
     7741 gctcgccgct gcttcgttcg cctatcatta catctggaaa catcggctga cgtatacatg
     7801 ggcagagctg caggggcatc tgtgcctctt cgccgagtcg cccgacggga tattcctggt
     7861 tttgcctccg ctggggagtg ggccgatcga tcagcccacg gccgaggcct ttcggctgat
     7921 gcgggcgtgg aatggggatt cgtccgtcac aaggatggag aatgtgccgg aatcgttcgt
     7981 gcccgcattg cgtgcgtcgg gttatgagac gggtgaaaaa gagccagact atctgtacgc
     8041 tgccgcagat ctggtcgacc ttgcaggaga agcgtaccga tcgcctcgcg cagcctgcaa
     8101 ccggttcgtg cgcgaacatg gcggggttct tgagccctat gattgtcgcg accagacggc
     8161 ttgcgtgagt ctgtttcgtg aatggagaga acagaagctg cggtccggat cggatgagtg
     8221 ggccaatgct ctgctggagg atgccgtcgg agcccatgag acagccttgt cggcacatag
     8281 tgagctgggg ctgaccggag cagtggtgcg agtcgggggg cgcattcggg cctacacgat
     8341 agggctgtgg ctcaatcaat cagtgttctg tgtcttgctg gaagtggcgg atcgggatat
     8401 tgtgggggcg ggcgcgttcg tgtttcgtga attctgtcgc caagcgcacg ctaaaggcgc
     8461 atgttggatc aatacgatgg atgattccgg ccttccgagt ctggcgaaag ccaagcgctg
     8521 gtatcatcct gcccgattgt tgccgaatta tgttgtgacg gagttccgac gatgacggcc
     8581 tcgccccttc caggtttccc tcgccgatcc tatccgtggc ttcccgtgct gattgtgggt
     8641 gtgacgattg ttgcgttggt gatcggcgtg gtcatgttgc gctcgatcga ggtgcggatg
     8701 gttgaagcca ccggagaaaa tctcacgctc gcgtcggcgg agattgcgga caaactcgac
     8761 cggctgctct tcgaacgtca tgccgatgtc cgcatgatgg cgcgggcgtt caccgaccgc
     8821 tctgccgata aaaaatatat caacgaatat ctgcagtgga tgaaagagac ctatgcgccc
     8881 gtctatctct ggctgggggt gacggatcct cacgggcgga tgattgcggc aacggattca
     8941 tccatcatcg gccaggatta cggccggagc ggctggttcg accgggtccg gcagacccac
     9001 acggtgcagg tcgatgaagt cgagatccat gaatcaaatc ataagatcga atcggtcgcg
     9061 tttaccgcgc ccattctcag tgtcagcggg cagtttctcg gcgcagtcac cacccggatc
     9121 ggcctgccga tgctggaaga tgttctcatc gaaacggtac gcgaaattca acagaccgat
     9181 ggcgcggccg gtcccttcga atatcaattc ttgaccaagg gcggtctggt ctttgtggat
     9241 tcctcttcct ccaacatcga ccgcgtcaat ttgcgtgaac tcaatctgcc ctcagtcttg
     9301 cggagcagtt ccggcaaggc gggatatgtt gaagaaatac acgttcgccg tcatgtcccc
     9361 gtcgtgaccg gctattccca gacgaaggga tacagcgatt attccggctt gcagtggacc
     9421 attctcttgc ggatcgatcg agacgtcatt ctgctgccga tccgggcgat gatgtggaaa
     9481 ctcggcattg ccggagtggt cgtatggctt ccgatggtgg gattgctgtt gtgggccacc
     9541 ggacgattgc gtgagcagca tcggcaggca cagcaagaga gcgaatgggc ccgcgcggcg
     9601 gaggcggccc tcttgcagag ccaggaacgc aaccgggtca tcgtcgatac ggcgttagac
     9661 gccgtcattt ccatggatgc gggcggcatc atcacggatt ggaatgcgca ggccgtcaac
     9721 atcttcggct gggaacgcga ggaagcgctc ggccgtcgcg tatcggagac ggtgattccc
     9781 gtccgggacc gggatgggca tgagcgagga ttgcggcatt tcctcgaaac cggacaaggc
     9841 gctcttctca atcgtcgcat tgagatgatg gggagtcatc gcgacgggca tgaattcccg
     9901 gtggaaatta ccatctctcc ggccaggctg ggcgacgcgt atattttcag cgcgttcatt
     9961 cgcgatatca ccgcgcgcaa acggacggaa cgccaactgg cttcccagta cgccgtcacg
    10021 cgcgtgctgg cggaatcgcg aactttggaa gaagctggtc caaaaattct ccaggccatc
    10081 tgcgaaagcc tggaatggga attgggcata ttctggcggc tcgaccggca gggaagtgtg
    10141 ctgcgttgtt tggatgtgtg gcagtcaccg ggactcaatg ccgaagaatt tgttctcgac
    10201 acctggcggc atacgtttgc gctcggcaag ggacttcccg gacggatttg gcaggcgggg
    10261 gagccgacgt ggatcaagga cgtcgtgcag gaagcgaatt tccctcgggg cggtgcagct
    10321 tcgcgcgtgg gattacacgg cgccttcgga ttccccgttc gagtcggaac cgaagtagaa
    10381 ggcgtcatcg agctcttccg gcgcgaaatc aaacagccgg acgagcaact cttgaagatg
    10441 gtcgccgacg tcggtctcaa gatcgggcag tttggcgaac gagcccgcgc cgaggatgcc
    10501 ctgcgacgca cggaagcgca gctgcagcag tcgcaaaaaa tggaagcggt cggacgcctc
    10561 gccggaggcg tcgcgcacga tttcaataac atgctgacag tgattcgagg ctacagcgaa
    10621 ctggtgctga gtcgtctttc cccgaccgac ggattccgga aggaattgga agaggtcaaa
    10681 aaggcggcgg atcgtgcatc cggtctgacc ggccaattgt tggccttcag tcgccggcaa
    10741 tttatcgctc cgaaggtgct ggacctgaac tcggtgatcc ataatatgga aggcatgctc
    10801 cggcgcttat tgggcgaaga catcgtcgaa ctctgtactg tgctggatcc gggattggga
    10861 caactgaagg cggatcccgg gcaggtcgaa caggtcatca tgaatctggc cgtgaacgcc
    10921 cgcgatgcca tgccggacgg cggccggctg accgtcgaga cggccaacgt gcaattcggc
    10981 cagcgccgca accgcccgcc gatgggcgcc gagcctggtt cgtacatcgc gctcatcgtg
    11041 cgcgacaccg gccacgggat ggacgaagat acgcagtccc acgtctttga accatttttt
    11101 actaccaagg aaaagggcaa ggggacggga ctgggattgt ctacggtcta tgggattgtg
    11161 aaacaaagcg gggggttcat tgaggtcgag agcaagccgg gccgtggggc cacctttaaa
    11221 atatttttcc cgcgtgttga agcggtcagt gaggaaacgg aatcagttgc cgtgggcggt
    11281 gattcggtca gagggcgcga gactgtgttg ttggtcgagg atgaaccggg cgtgcgacgc
    11341 ctggtcaatg aaacgttgcg gctccatgga tatacagtgc tggaagccag gcatggcatc
    11401 gaagcattgc tgacgggtgc caaacatgcc ggtcccatcc atttgctcct caccgatgta
    11461 gtcatgccac aaatgagcgg cccggaagtc gccgaaaaac ttgcgacggt ccgtccggaa
    11521 gtcaaagtgc tctatatgtc cggttatccg gatcacccgg ccttctctaa gggtggcatt
    11581 gataccgagc attcctttct gcagaaaccc ttcacgccca cgacgctggc ccaaaaagtt
    11641 cgtgaagtgt tggatgggtc gaaggtcagt tgacccgagg tttctgtcgg tcgcttgaac
    11701 ttcctgccgg tttccgttta tcgtggcgca ccatgcactt tattcaattt caggcaggag
    11761 tggcggaatg agcgaggggc gagcagcgac ggcgccaaaa ggacaggcac aagacatcga
    11821 ccattaccgg atcgcgtgcg agccgtttta cgccgacgtg cggggcgagg tcgggctctt
    11881 taccattgcg gcgcaaagcc gcatgccggt gatgctcaag ggccccacgg gctgcggaaa
    11941 aacgcggttc gtccagcaca tggcctatcg gctggggcgt ccgctcatca ctgtcgcgtg
    12001 ccacgaggat ttgaccgctt ccgaccttgt cggccgctat ctcttgaagg gacaggagac
    12061 agtgtggatg gatggtccgc tgaccctggg tgtaaagcag ggagcgattg tctatctgga
    12121 tgaaatcgtc gaggctcgca aagacaccac ggtcattatc catcctctga gcgacgaccg
    12181 gcgcctgctg cccattgaaa aaaaaggaca ggtcatcgag gcggtggatg agttcatgct
    12241 ggtgatctcc tataaccccg gttatcaaag tattctgaaa gatctgaagc aaagcaccaa
    12301 gcagcggttc atggccatcg agttcgatta tccgctgccg gatatcgagt gccgggtcgt
    12361 ggcgcatgaa gccggagtca gtcccgagat tgcgcagcga ctggtcaaga ttgcggagaa
    12421 ggttcgtaac ctcaaaaatc acgggcttga agaaggcgtc agcacccgat tgttgatcta
    12481 tgcggcgacc ctgatcaagc agggcgtgcc cgcggatcgc gcgtgcgatg tcgccattgc
    12541 caggccgatt accgatgatc cggacatgtt gcgcagcatc atcgaggtcg tgaaagcgat
    12601 tttctagccg ctcgtttttg cacctcaccg actctgcgtg cttcacaatg ttgtgaccac
    12661 ccacaattcc ggccgggagt ccaaatcctc ggcagcagcg caggtcgttc gcaccacacc
    12721 cgagggcgcc gttatttccg ttcatgtcca gccgaaagct tcccggactc aatgtgcagg
    12781 gcttcacggt gatgcagtca aaattcgtgt ggctgcaccg cctgctgatg gtgcagccaa
    12841 cgaagagttg tgccggttcc ttgcccgcac atgcggcctg cccgtgagcg gcgtcgagat
    12901 tctcagcggg acgagtagcc gccagaagcg aattttactg aggggacgtt ctgccgaaca
    12961 ggtgcgcgca caacttcaac ttgagtaagc cgcggttggg tcgcacctct gaatgcatga
    13021 ggcactcttg atgcgaggat gttatgcacg gtgagccggg tgtcgagcta tggccgcggt
    13081 cgtctgttct gagaaaaatc aggtccatca tttttcgatg gtcactgtcg ctgattgtcg
    13141 tggtcgtgag cggatgtgca gggcctgaac ccatcttcaa gtcgactacc tatttgcaac
    13201 tccacgggca gcaacaagcc caggatgaag ccgcggtctg tgcggtgaag gccgagcggg
    13261 ccggattgca gcatggaacg aatcgcagcg ggaatgccgg cgccggcgcc gcgctgggcg
    13321 tcatcggtgg ggcggcagta ggggcctcgg caggactggt cggggggcca actgggattg
    13381 ccatcggtgc ggcagcgggc ggcgccgtcg gtggaatctt ggggctgttc gccggaacct
    13441 acaagccgtt acacccgcga caagattatg cggcattcgt cgaacgttgt ctgaaggaaa
    13501 agggctacga gaccgagggg tggcaataat gatcggtttt cgatcaaagg ccgtgcaggt
    13561 tcagtcgtca aaatgtaaag cagcctgaat agtcggccat caggcattga acacgaatag
    13621 aaatccgttc cagccgctcc aattgttgcg gcgtcggggc ggaaccgcgt acctcccgca
    13681 gccattcgag atcctgctcc aattttctca acgaccagcg tgatgtgcca ggaatgcgcg
    13741 tctcctcgtg aagcgcctgc tccacaaggc tggtgaacga ggcgacttca tcggcaaatt
    13801 cgacgcggtg ggcatcaaaa gcatagggcg cctcgtcctg cgacatgagc gcgagcagtt
    13861 ggcggagcca ttccaccgtc gcggccatgc gctcgtagtg gagcgtgctg gcgacgtcgc
    13921 ctgccgtgtg ataacggggt gatcgcgcag cggagagaaa caggaatggg accttctggt
    13981 tgcggaagac atcgtagtcg ctgaaggcct tgtgaccatg gtcgggaatt tcttcgacca
    14041 ggtgaattcc tccacggtag atcgtgaggg gtgagacccg ggtttcagtg acccgtcgat
    14101 acaacgcagg gcttttctct gctcccgtgg caaaaatcgc gtccttcagc ggagcccaat
    14161 gcacgcctcc catcaaatcc atgatgatcg cggcttgaag attttccgca gcgccgactt
    14221 ccggcggcag gtggtgaaac aaaaactgtg atcccatttc ggccgttccg aagtagggaa
    14281 gttcctcacc gttgaacgcg acaaacatga tgccgtggcg tgaaagtccc gtcagatttc
    14341 tggctgtctc aatcaggatg gcgatcgagg aggcgttatc gtcggctcca agaaagggat
    14401 accccagatg atcgtaatgg gccccgatca caatccagcg ggtgcgagct gtgtgatcga
    14461 tcggcgggat caccccgatg acgttgtcgc ccatgcgatc cgaaatggtc tgccgatagc
    14521 ctccaagcga ggcaagcggc tgcagtccga cgagacgaaa ttgttcttcg atgtattggg
    14581 ccgcctggcg gttgcctggc gttcccggtt ggcgaccagc cagtgcggga ctcgcgagga
    14641 aggagacgta tgactgcaat cgttgcgccg gagctgtcgt gacgggcaac gctctcggat
    14701 caagagcctc cattgtgtgg aggcagccgg ccatactcaa agaggtcaat acggcgacaa
    14761 ctcccaagcc atagcgaagg ccgactatcg gattgcagca aaaccggctg atcacgattg
    14821 tgcggaggaa tccggcgtag ccggggattc cggcaccttc ggagccatgg gcagcgcttt
    14881 gtggcgaagt gctcggcctt tgcccggagt cggatcaggg acgaggccgt aacattggcg
    14941 tccctcgtgg tcttcgggca agtactccgt aatcggcagc ccttcttcat tgacgaagag
    15001 caggcaatgg caatatttgt aaatttgcat ttcgtcgcac gcacacatcc agcgacgcag
    15061 tttggcctcg gcttgtttat cggggtagaa attgcagggg cagagcggct ttcccaactc
    15121 atcgacgtgg gcggctaacc ccaacaccac ggcgttggtc acggcaggat tcgggtgcat
    15181 ggccgtgccg ctcttctccg cgaagccttt cacatacttc cacatcttct cgagactttc
    15241 tttgctcggc tcagccattc cgtcccccgc gtgacattgg ttcagtgaaa cagtcgatcg
    15301 gtaccaggcg gtcgcctgcg acgacacagt ttacaagcga aattgtgtcc tttacaatcc
    15361 acgacttccc tcaaaatgga tcacagtaca tggcacccgg gcactccttc ccacaactta
    15421 ttgagcgatt ggccgaccaa ctcgggccgg cttccgctac gacaatggtt gacgccatcg
    15481 ttgcctcggc caccagaccg gatgcgccgg cgggggtgtg gctgttgctg gaggagctca
    15541 cagacgctgc gccgaaagcg gccaggggtg cgatcgaggc tctgttggaa ctgcaacgcc
    15601 ggggtttgct ggccgaggtg ctgccatggc tcgacctggg cgtagccatc gcggctgatt
    15661 cgggagcgtt ggcattacga tttttcaagg agagtcccct cctgctcggt ctactcgatc
    15721 cgcctcagcg agccgtggta ttggctgccg gtttggagtt ggctgaccgc caggccaatg
    15781 tggcggtgga atttattcga gttgcgccgg aagttgtccc cgttctgcct ccagccgatt
    15841 ggccgacgtg gatggaactg gcctgtgagt tgtcagagac cgattttgcc ttggccgtgg
    15901 agtatatccg tcagattcct gccatcgccc gcgtgctctc tctggatacc gtacgagcct
    15961 ggatgcagtt cgggatgaca ctcattgtcg acaatagcct cggcaagccg gactatctgg
    16021 gagcgctgga attcttccgg acgagtcccg gcatccttgc ggatattccc gatcagatat
    16081 cacgccacca agttattcgc gtgggcgcgc agatagcaga gcggtcgccg gagatgggta
    16141 ttgcccttct gtcggaagcc ccgtcgattc tccgcggtct cccgactgat gaatggcgga
    16201 ggcaggtgct gcaatacggt ctgatcctgg cggaacgcga tgccgagaca gccttggcct
    16261 atatgcgccg ttgccctgaa ttggttgcat tgattggatc aggtgaaggg gcgcaacaga
    16321 agtttcagtc ctggtttgct tccgggatgg acgtgctgga gtacagcgtg gaagggggcc
    16381 gcgcctactt tggcatggag tccgaaaaag cactgggcgc gttatcgcag gccatgagcg
    16441 gggtgccgtt gcggcagatc gccaggcggg tcaagttatt cgcccaggcc ctctgcggcc
    16501 gcgatctacg gatttacgat ctgcccgact cgctggaatc agcgcaaccg atgccacgtg
    16561 ccacggtcag cgacgacggg cggagcatcg ggttgccgtc gctcgtcagg cggcactcca
    16621 cctatgagga gaatgtccgt ctctatatgg tcatggccgc gcatgaggca gggcatttgg
    16681 aattcggcac cttcgatctg cccctcgccc gactggaaga tgtgagtaaa gaactgacgc
    16741 aacgttatgg acgcccggcc ttacgggaag tccgtacttt aggcgatatg tttgcacggt
    16801 atcctcagcc agggctcatc cgcgatctgt gggcgctcgt cgaagatgcc cgagtcgaat
    16861 atttgctgcg tcgggaatat ccgggcctga gccgggattt agccgtgatc gcaaaggatg
    16921 cggtgcaggt tcgaagtctg gcgcatggca tgacggtgcg cgaattggtc gtcgatcagc
    16981 tcctgctcct ttccacggtc gaggccggtt ccctgccgct tcctgatgcg ctcaagcgcg
    17041 agatcatgca tctctggagc ctttgtcaaa ccatcttcca tccgcaggcc actgcggagg
    17101 aggccgtgcg attggccgac cgtctctatg tctcgatgga tgagttattg gccatccgtc
    17161 gcgaggctat tcccagtcca gatgaagcgg aatcgcctga acaatcaatt cctgcgccga
    17221 aagcctcgga ggatctttcc gacacgtatc gtccaatgga caactgggac tatcgtggcg
    17281 cgatggaccc gaatctggtt cgagaccgca cggaatcgac acctgaacag agtcctgcgt
    17341 ccggccaggg ggatagtgaa ggcggagctg gactcgccgg tgattcaggc ggatcgtctg
    17401 gtgccggtac ggcgcgttcg cagcagatgt ctcaagagat gttggtgccg ggtcgtcgac
    17461 agccctcgct ggttgaagag atgttggcgg tggaaggtga gggcgcgcgg ccacaagatg
    17521 atcagactga gacggtcaag gcggtccgct atcgggaatg ggatgccgcc attcaggact
    17581 atcggatgaa ttggtgtcgc gtggtcgaac gggaggcggt cgaagggtcg tcggattttg
    17641 tggaagggac cttggcagcc cagcgggggc cggtcgcgct cctgcgccgc tatttcgaaa
    17701 gcctgcgtcc cccgggattg cggcgtgttc caggccaagt ggatggtgaa gacctggata
    17761 tggatgccgt catcggccga ctcgccgata tacaagcggg cattgagcca tcggaacgga
    17821 tctatgtgcg gcgcgaaaag cgggaacgtg aggtggccgc ggcgtttttg gtcgatctca
    17881 gcgggtccac cagccgccag gttgaacggg gacgacgaat cattgatatc gaaaagcagg
    17941 gattggtcct cttgtgtgaa gcgctgtctg cgatcgggga ccaatttgcc gtctacggct
    18001 actccgggca gggccgccat ctggttgatt ttgtcgtagt caaagatttt gaccaactag
    18061 tgactgggcg ggcgggcgcg aagctggggg gcatggttcc cttgcagcag aatcgcgatg
    18121 gtgcggccat tcggcatgcg acgaccaagc tcctcgctcg tcaggcaaaa actcgcttgt
    18181 tggtcatgat cagcgacggc cgtccgttgg atgacggata caaggacgag tattccttgg
    18241 aagatacacg catggcgctg cgggaagccc gggcgagcgg gatcgaaccg gtctgtatca
    18301 cgatcgacaa acaggcggat ccctatcttc gacggatgta cggggatgtg cgctatgtgg
    18361 tgattgatcg ggtggagggg ttgccggaga agcttccaag gatttaccat cggctgacgg
    18421 cctgaccggt tgcacatagg gccttttcag cattggagca tacgaatcat gattgagcag
    18481 tctcccagac cgaccgtgcc gccctggctg tataaattgt tcacgggcca tcaatatccc
    18541 tatgtgagac ggcaggccaa gtttgcgaat cgggacttca agcccggaga agagcgtccg
    18601 gagcctacgc gagaagcgat tgatgccaag ttttgggaaa tctatccgcg gtgcaccgcc
    18661 aaaattttgc aggaagtgaa agccggcatg atcgtggtgt ttcacgagct gggtgaatat
    18721 ccgccgggcg ggtatcagga cctggtggat gcgccggaag aatttcttgc cgcgaagtac
    18781 gggaaaaaga aaattaaagt gaatttctat gacggcgata attttgtctg cacgatcaat
    18841 ttcaaggtcg gcggctggac ggggcacgaa ccggcgtgaa atgtgtgaag caggtgcgaa
    18901 ggtgactttg cacccgagac ctcaccgttc acgcttcacg aggtggaaat aatgggacga
    18961 ccaaaaatca cagtggtggg cgcggggaat gtcggtggaa cggccgcgca gcggttggca
    19021 gagaagaatg cctatgatgt cgtgttggtc gacatcgtgc cgggaattcc acaaggaaaa
    19081 gcactggata tcactcaggc cggtcccgtc tgcggataca gtacccgcgt ggtcgggaca
    19141 aacggatatg atgagacggc cgggtcatcc atcgcggtga ttacgtcggg gattcccaga
    19201 aagccgggca tgagccggga tgaactcctg ggcaccaatg ccaaaatcgt caagactgtg
    19261 gtgcaggaat tggtgtcacg ttcaccgaac atcattttga tcctggtgac gaatcctctg
    19321 gatgccatgg tgcatgtcgc gcgaaaagtc agcggcctgc ccaagtcgcg cgtcctcggc
    19381 atggcgggcg tattggacac cgcacggcta cggtcgtttg tcgcggagga gcttgatgtg
    19441 ccggggacgg atgtgcaggc gatggtgttg ggtggtcacg gagataccat ggtgccgctc
    19501 gttcgccaaa cgaccgtggc aggtaaacct atcacggatc gattgtcatc tgagcgtctc
    19561 gcggccttga tcaagcgcac gcaggacggc ggagccgaaa tcgtgggatt actgaaaacc
    19621 ggcagcgcat tttatgcgcc gtcagcctca gtagttgata tggttgaggc gatcatgaag
    19681 gatcagaagc gtgtggttcc ctgcgcgatg ctctgcgaag gtgaatacgg attaaaggat
    19741 gtcatcgtcg gcgtgccggt caggctcggc cgcgggggtg gggaatccat tgtggaatac
    19801 gatctgacag tcgaggaacg gacggcgcta caggcttcat ccgatgcggt gcgagacctg
    19861 tgcggcgtgg ttgatcgtct gttgacggcg taggtagtgc ccaccaagac agcgaggata
    19921 gcaggttgct tgacaaggct cggcaccctg cagtagagaa cgtggttggc agtaaaccgt
    19981 tacagttggg gggcgtatga aatttctgga ggatccgtat cagacattgg gcgcaggagt
    20041 tgcgcttgct gtcggattga tagtcgtcta tctaggtatg gccggagtgg gagcgggcga
    20101 ggccgattgg ttcggtctgg ttgtccgctg ggtccacttt ttggcgggca tcacctggat
    20161 cggactgttg tatttcttta acctgatcaa tgcgggcttt ctcaagagct tggacgggcc
    20221 gacgaagaac atcgtcattc caaagctgat gcctgccgcg ctgaactggt tccgtcatgg
    20281 tgccacggtg accgtgcttg cgggcatcgt gctctatggc tacctctatt ccaagggggg
    20341 cactggggcg ttggcactcg gcatcggtgg gctcctcggc atcatcatga tgggaaatgt
    20401 ccacggtatc atttggccga atcagaagaa ggtcattgct gcggtggccg ctgccgcaca
    20461 ggggacgccg gctccgccgg agatggctca gtggggtaaa accgcgctct atgcttcgcg
    20521 gatcaatttc ctgttgtcca tcccgatgtt gttcttcatg ggcgcaggga gccatttgaa
    20581 gtaacgttac gcgtggacag aatgaagggg gattggtcat ccgagtgggt gatcagtccc
    20641 ctttttcatg cgctcgcctg tggtgtgagt tatcagcccc tcggagcgag tctttgggct
    20701 gagttgtcgt aggtctatca ggcctaactg attgagattg aggcctaatc aggcgaacgt
    20761 ggcttgacgg ctctcgaagc gcagccgtat agtagctacc tgctaacctg ggggtgtaac
    20821 ccccgaaagg gaacaacgtg accctacctc aaccacgggt attgcagaaa cttgatgggg
    20881 cgccatggga aatcgacccc tacctcaaga ccggcggcta cgacgcatgg cgaaagtgcc
    20941 tgaaggaact cacgccggct gatgtcgttg gcgaaatcaa gaaggccggt ctgcgcgggc
    21001 gtggcggagc aggatttcca accggtatca agtgggacaa ggttcttaac catcgcgtgc
    21061 cggagcgcta ttttgtgtgc aatgccggtg agcatgagcc gggaaccttc aaggaccgcc
    21121 accttctcaa acatattccg catcagttga ttgagggctg tctgatcgcc tcccgaacgg
    21181 tcaatgcgaa ggcgtcctat atctacgtca accatgagta cgaagaagaa gaagcgaacc
    21241 tgagaaaggc cattgctcag gctagagaac gaggtttgtt gggcaagaac attctcggca
    21301 cgggtgtgga tctggatctg gaagtatttt ccggccacgg cagttacgtg gcgggagaag
    21361 aaacggcgat gttggaatcg atgcaagggc gtccggcgat gcccaggcag aaaccaccgt
    21421 tttatccgac ggatttcggc ttgtacggga agccaacgtt ggtgaacaac gtcgaaacct
    21481 tgtgcaacat tccccagatt ctaaaaaatg gtgcggcctg gttcacgcag gtggggacag
    21541 agaaatgtcc cggcaccatg ctgttttcac tgagcggttc gatcaatcgg cctggcgtct
    21601 atgaaatgcc gatgggcgtc accatcaggg atctcattga aacctgtggc gggggcgttc
    21661 cgaacgggcg caagatcaag gcggttttcc cgggaggacc tgccttctcg atggtgacgg
    21721 cagaccagtt ggatctgccg atggacttcg actcgctcaa gaaagcaggg accgggttgg
    21781 ggtcggctgg gaccattgtg attgatgatg ccacctgtat ggtagcggcg accctcaaat
    21841 attccaattt cttcaaggga gaaagttgcg gacaatgtcc tccctgccga atgggtacaa
    21901 tcaatctggc gacattggtc gaaaagattg agcgaggaga gggaagccaa aaggatctgg
    21961 actctctcct gcagctgtgc gggttcgtga agggaacggg atattgcacg ctcatcaccg
    22021 gtgccgcggt tctagtgcaa agcagcctgc ggttattcca gcatgaattt gaggaacata
    22081 ttcgcatgca ccgttgtccg ttccagtcag ctcagactgg tgttggcgcg aaggcgtaga
    22141 ggagtcggcc catgccgcgc gtgagctttc ttcatccgga agggcgtagt ggggaggttg
    22201 agtcgaacct caccttgctg gaagctgcga aggcccttgg ttttgggctc aatcacgact
    22261 gcggagggaa cgcatcctgt acgacctgcc gggttgaagt gcaaatgggc ggagagaacc
    22321 tgtccgagat tgatttcgac gagcaggatc tcctcgatcg cgaagccctc tctgagccgt
    22381 ggcatcgact tggttgtcag gcgagggtgt taggtgatgt agtggttcgc gttcccgaaa
    22441 ccaagtgggt gcaacccaca tcagcgtcat ccagccagtt cgggaaaaaa ggggccgggc
    22501 ttccgtaagt tcccgcgaga tggtaaagta acataacgtg ccgaacatgc agaccagaag
    22561 gaggaccaac ggatggtaac gattacgcaa ttggcagagc agaagataaa agaactgatg
    22621 accgaagaga aagatgtggt cggcctgaga atttatgtgc gtggcggtgg atgccacggg
    22681 tatcagtatg gaatggcctt cgaatcaaaa atggccgatg atgatacggt cattgagaaa
    22741 ggtgatgtga aggtcatcat ggattctcag agtgccccgc tgttgcaggg tgcggaagtc
    22801 gattacgtcg acagtctgca agggtccggc ttctccatta agaacccgca agccaagacc
    22861 acctgtggct gcggcagttc cttcagtgca taagagcctt ccggttgtgc ttcaaccgga
    22921 acgccgatgt ttcgttgagt gacgtatcag gccgggagtg gctcccctct ctagcgggta
    22981 gctctcccgg cttgttcgtt ttgatgatct ttctggagaa tcgtccggat gtccgaagcc
    23041 accattacgc gccgctatcg tttttgcgcc gcgcatcgct tgcacaccga tcagctgtcg
    23101 tctgaagaaa attggaccac attcgggaag tgcaacaatc ccaatgggca cgggcacaac
    23161 tatgtcgtgt ttgtctcggt caggggcgac atggattctg taacccatca ggtggttgac
    23221 ctgtcaaagc ttgatgaggt ggtccagcga attgtcgtgc gacgcttcga tcatcaggac
    23281 ctgaacaaag atccggagtt cacgacacaa acgacgaccg gagagaatct cgtcttactg
    23341 atttggaatt tgttggtaaa tgaagttccg ggggggcgtc tggtgaaagt tggtgtgatc
    23401 gagacgcgag acaactattt cgaatattcc ggatccgcga agcaggtgcg gagagaagat
    23461 ggagtgaggc atggctaaag tcgtttccgg gtcccgcgcc agacggtcgc gtaccactgc
    23521 aacgcccacc gccgatgacc cgatcgaagg gttgatgacc aagcttttgc tggaactggg
    23581 ggaggagcct ggccgtaacg gtctactgaa tacgcccaaa cgtgtcgcga aagcgatgcg
    23641 gtttatgacc caaggctatc gtcaggacat cgatcacttg ctcaatggcg ctctgtttcc
    23701 catcgagtac gatgaaatgg tgatcgtgaa ggatatcgat ttcttcagca tgtgcgagca
    23761 ccatttgttg ccgtttttcg gaaagtgtca cgtcgggtat ctgccgaaca agaaggttgt
    23821 cggactcagc aagattccgc gggtcgtcga tgccttcagc cggcgcctac aagtccagga
    23881 acgcttgacc gttcaaatcg ccgaaacgct caagaaaaag ctgaatgccc atggtgtcgc
    23941 cgtggtcatg gaagcgcggc atctctgcat gatgatgcgc ggggtcgaaa agcaaaatac
    24001 cgtcgccgta agcagctcta tgctgggagt attccgcacc caacagcaga cccgagaaga
    24061 attcctcaag cttattcgtg ggagcagcgt caaagacgga ggctaggatc gcctgccgtt
    24121 tgcccgcacc ccttcgacga atccccgcaa gagatcatta aacagctcag gttgttcgca
    24181 gttgctcaga tgcccggcgg ccggtatgac ggccagccgg gcatttggta tgtggctggc
    24241 cattatttga gcgtcgacga gcgatgtcgt gtggtcttcg tctccgatca cgacaagggt
    24301 tgggcaggaa atggccgtca gatgggcaac ggaatcactc cgttccgcca tggccatcaa
    24361 atcgaccaga attccgctga ccggagtgtg ttcaattgtc cggcgaattt gctcgaccag
    24421 ttcgggttta ctctttagtg acgtggcgcc gagcaacttc ggcagcatag tattcgccac
    24481 cgcctcggtg ccttgggtat aggcggtttg cgccagatga aagcgtcctc tctttccttc
    24541 cggactgtcc tcctgtgctc gagtatcggc gagtaccaac gcacagagcc gatcgccgca
    24601 tttctttgag aatgccaggc tgacgtatcc acccattgag agtcccacca ggacagcctg
    24661 cggaatgttc agatggtcga gcagggcggc cacgtcgtcg gcatactgtt cgagtgaaaa
    24721 ggaccacaga ggggcatccg actcgccatg accgcgaaaa tcgagcgcga tagttctaaa
    24781 ttgtgtggag agcgcggcga cttgcggcgc ccacatggag cgattcaacg gaaacgcgtg
    24841 cagaaacacg agtgggacgc ctgagccgcg gtcgtcatat gccaatcgaa tatcctgtgt
    24901 ctgaaaaaac atcggtcccc ctgccaagaa ttgatgccgg atgggtggta gcattgccag
    24961 ggttgagaat caaggggatg gttgagtgag acgggccagt ttgcggtgtt tccgtggcga
    25021 cgtatagaat gcagaaggcc ttgcacctga gatcaatgat gccagctcat gattcgacag
    25081 gcgatttatt cgcttcatcc cagcccgcgc caaggataac accttccggg aaagtcccct
    25141 tggcggaacg cctgcgccct cgaagtttcg atgatctcgt gggccaggac gacgtggtag
    25201 gtcctggacg tccgttgaga agtgcaattg agcaggatcg gctttcttct gtgatcttct
    25261 ggggacctcc gggttgtgga aaaaccacgt tggccggctt ggtggctcaa tatacgaaat
    25321 cgcagttcgt gccgttctct gcggtcacgg gagggatccc ggaactacgc gagatcatca
    25381 aagctgcaga gcagcggcga acgaggggga tggcgaccat tctctttgtg gacgagatcc
    25441 atcgattcaa taaggcgcag caggatgcct ttcttccgca tgtcgaacgg ggaacggtgg
    25501 tgctgatcgg cgcgactacg gagaatccgt ctttcgagct cattgccccc ttgctttcac
    25561 gatcgctcgt gatcgtgctc cagccgctaa ccaccgaggc actcggctcg attttagatc
    25621 gtgcggtggc tgataccgac cgtgggttgg gctcgcttcg cctcacaata cagcccgctg
    25681 cccgcgaccg attgattgcc ttcggaaatg gagatgcgag aagcctctta acaacgctgg
    25741 aatttgtggc cgggcaagcg ccggtcggca tggatggccg ccggatcatc gatgaatcgg
    25801 tgttggaggc cgccctgctg aaaaaggccc ttcgctacga taagggtggc gaagagcatt
    25861 acaatttgat ctccgcctac atcaagagcc tgcgtgattc cgatccggat ggggccctct
    25921 attggctcgc gcgcatgctg gagggaggag aaaaccctcg atttatcgcg cgacgtatgg
    25981 tgatttttgc atctgaagac atcggcaatg ccgaaccgca ggcgttagtt gtggctaatg
    26041 ccgtggcgca agcggtcgag tttgtcgggc tcccggaggc acagatcacc ttggctcatg
    26101 gaacgacgta cctggcatcc cggccaaagg acaatgcgtc ttatgtggga cttcaagagg
    26161 ccattcgaga tgcgcgccaa cacggcaatc tgggcgtgcc gttgcacctt cgtaatgccg
    26221 tgacgtcgct catgaaagag atcgggtatg gccaaggata tcggtatgtg cacaatgacc
    26281 ctgcggccaa atccgagcag ggccacctcc ctgaaccgct caagggcaag cggtattatc
    26341 gtccccggac ggcccaagat catgaagaaa ggggctagac aaagctggtt atacggttat
    26401 acttagcacc gaggtcgcta tggcgcgtca gaccaattca accgaaagtg tcagtgaacg
    26461 ccggaagtat gtccgggcca ctctggtcgg gtcagccctg gtctccccac agaacggggc
    26521 caagggattt acggcggttt tgaataatgt gaacaagatc ggcgcgggat tgcattcgaa
    26581 ggaaaccctg ccgattggtg ccaagatcac ggtctccttg gcatttctgg atcccgatcg
    26641 cgttgagcag caggagaagt tgagcgccac ggtggcctgg gccaaaccgt gggagaaggg
    26701 gatgttgctt ggcgtggtgt gggatgatct ggtgacgaaa gaaaagaacc gctggttgta
    26761 ttactatctg gaagagacgc tgaagtcgac ggactaaccg agtgccgtca gtttttcccg
    26821 taccccctgc aattcctccg acaacgattc ccagcgggcc gtgagccgtt ccagctcttt
    26881 cttccaggtc tcctgctctt gttgcaattc gctccagcgg ccaagttcct tatagagcgc
    26941 cggatccgcg agttccagct ctctcgcctt gaccttggat tccgtagagg cgatctcaga
    27001 ttccgcgcgc gagacttgtt tctcgaggcg tgcctgggtt ttgttcaagt cccgccgttc
    27061 tccgccggaa gacttctgtt ggacctgcga cgccatggcc ttcgtgggac ctgacgattt
    27121 gtcattctgg gcggcggcaa gttccgcgct gctttccttg atcgattcga attcctgcgc
    27181 cttcttccac aagaaatact cgtagtcgcc caaataggtt ttggcctggc cttcatccac
    27241 ctcgacgatc atggtcgcaa cgcgggcgag aaacgttgga tcgtgagaaa tgaacacgat
    27301 tgtccccgga aaatcggtca tagcatccgt caacatatcc accgaggccg gatcgaggtg
    27361 gttggtcggc tcatcaagca aaagggtatt ggccggttcc accagcatgc gagccagggc
    27421 cacccgattg cgctcgccgc cgctgagtgc cttgatcggc tttttctgat cgtcgccgct
    27481 aaaaaggaag gctccggcga tgcctcgaag aaaattcgtt tcagcctgcg ccgagacttc
    27541 ggccagtgat tccagaatcg tgtggtcctg gttcaaggat tcggcctggt gctgagcaaa
    27601 gtagtgcagg gtcactccat ggccgacatg gcgggatccc ttctcgaacg gcaatacgcc
    27661 agccagcatc ttgagcagcg tacttttgcc ggcgccattt tcacccacca gtgcgatgcg
    27721 ctggccgcgt tccaccgcga aattcaggga tcggtaaatg accttctctc cataactctt
    27781 cgcgacgccc ttgagctcga gcacgtgccg gccgctggcc gcgggcagcg gaaacttgaa
    27841 ccgcacccgc ttggtatcgc gttgccgttc gatcagcttg accttatcca attgcttgat
    27901 gcgcgactgc acctgcttgg ctttgttggc ctgatagcgg aagcggtcga taaagctctg
    27961 cacgcgcgcc acttccttgc tttgccgatt cgccgccgcc tcaatctgag catcacgggc
    28021 cgctcggagc tcttggaact tcgtatagtt cccacgatat tcctgaaggg tccgatcccg
    28081 gagttcccag atatgcgtgg cgatgccatc caggaatttg gtgtcgtggc tgatcacgag
    28141 caacgtcagg ttggattcca gcagaaaccg ttcgaaccac cgctgagtcg gtttgtccaa
    28201 gtggttcgtc ggctcgtcca acatgagcac gtcggggttc gagagcagga gatgcgcgag
    28261 cgccacgcgc atgcggtatc cgccggagag gttctcaatc ggcctggaga agtccgcttc
    28321 ggtaaaccct aacccggaaa gaatacgttc ggcttcatgt tccgggtaga tgtcgcgatg
    28381 ggcagcatcc aacacagttt tcccgacgat agtttccaat tcctggggga ggtagccgac
    28441 gcggagtcgc gggcgtttgc ggatggtgcc tttatcggga gactcttcgc ccagaatcat
    28501 ccgaaagagg gtcgtttttc ccgcgccatt ggggcccacg agaccgacgc gggctccagg
    28561 tcgcagatgg gcggtagccc cttcgagcaa cactttcgtg gaatattgct tatggacaga
    28621 ttcaagctga agcatggatt agtagtactc ggggtctgag gtgaaacgtt cggcgaggta
    28681 cccgctgcgg agtgtcagcg cccccgtgtg aagcggcggc tggctaagcg tatgactcgt
    28741 agagttcgga tatccccgca cacatcacgg agtgttggtc ggacaagctt gttttggtgg
    28801 agctggccgg gattgaaccg gcgacctcgt gaatgccatt cacgcgcgct cccaactgcg
    28861 ccacagcccc acgcaagctt ggatcttatg tgcacaggca gcgagaaaac gaatgctgct
    28921 gcagacgtaa ctccgcaatc tagcacgggc ggattttgtc agtcaagaaa agggtggtga
    28981 ggcggcgatg tgccgcgccc ttttgtgctc gcgcaacgcg cggcctcaga aggccctcgt
    29041 tggacgcgcg caatgtaaag ggcgcggtac atgccgcctt gtgagagcaa ggaagcggcg
    29101 gagaagatcc aggatcatcc gccgtctaag agaatgcggc gtcgggagga agaataccca
    29161 gcctatccgt cttaggaagc acgctggagg tgacgcaacc aagggcggaa gcttgttctc
    29221 gaaaaccctg cttgacaaac cgcggtgtga atcctaccat gatgcccttc cggctctgat
    29281 cagtacgagg tcagagcctt tttttcgagt tcagacggga agaaagagca gaggcagcga
    29341 acaatggcga atctcgtcat catcggctcc caatggggcg acgaaggtaa agggaaaatt
    29401 gtcgatatcc tggccaagga tgccgacatg gtcgtgcggt accagggcgg ctccaatgcc
    29461 ggccatacgg tcatcaataa acgggacacg ttcattttcc atctcattcc ttcgggcatc
    29521 ttatatcgtg gcactcggtg cctgatcggt aacggcgtcg tggttgatcc cggagcattg
    29581 atcgaagaaa tggatcatct ccaaggccag ggcgtcaaaa tcggaaaaaa tttcgccgtc
    29641 agcgatcgtg cccatttgat cctgccgtac cataaggcca tcgataaagc ctcggagcag
    29701 tctaaaggtg tccgtcgtat tggaaccact gggcgtggga tcggcccgtc ctacggcgac
    29761 aaaatggcgc ggatcggcat tcgcatgggc gatttgctga atcccccgct cttcaagcag
    29821 aaactggaag aaaatctcgt cgacatcaat tggctccttg agcagctgca caaagtggac
    29881 tgcttcgagt tggaaaaggt ctaccagcaa tacatggcct atgctgatcg actgaagagc
    29941 tacatcctcg atacgacgat ggtcgtcaat aaagccgtcg acgctggaaa aacggtcctg
    30001 ttcgaaggcg cgcagggaac gcacttggac gtggacttcg gcacctatcc ctacgtcact
    30061 tcgtcgagtt cttcggccgg cggcgcctgt acgggaaccg gggtggggcc gacgaaaatc
    30121 gaggcggtga tgggcattac caaggcctat acgacgcgcg ttggcagcgg acctttcccg
    30181 accgaattaa ccgatgaagt tggcgggtgg ctccaggagc gcggaaaaga attcggtgcc
    30241 acgaccggcc gggctcgccg ctgcgggtgg tttgacagtg tcgtggtccg acatgcgacg
    30301 agagtcaacg ggctgtcttc tctcgcggtc acgaaattgg atgtgttgga cggccggaac
    30361 gagttgaaga tctgcacggg ctaccgggtg aacggcaagc ttcatcgtga catgccgtcg
    30421 gacttgctcg cattgaccaa ttgcgagccg gtgtatgaac gcattcgtgg gtggagcgca
    30481 cccacaaccg gtgttaccac gtataagaaa ttgccggtgg aagcgaagcg gtatctcacg
    30541 aggatcgaag aactggccga gtgtagaatt gatatgatct ctaccggttc acggcgtgat
    30601 gaaaccatca ttctcaacaa tccgctcaag gcaggccgcc gcaagcgagc gccacgttca
    30661 cgatgatcgc tgtgtttttt gcgtcttccc cgatgtgcgc cgtagcgata caggacgcgt
    30721 cagtggtaag atccctcccg tcacgatcct cgcgtgacga tgtgtcgtct ccatcttggg
    30781 agagtcggta gctcagctgg tagagcatcg cccttttaag gcgagggtcc tgggttcgaa
    30841 tcccagccga ctcacca
//
LOCUS       DAOQPD010000045        30461 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_668_length_30461_cov_18.509735, whole genome shotgun sequence.
ACCESSION   DAOQPD010000045 DAOQPD010000000
VERSION     DAOQPD010000045.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 30461)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 30461)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30461
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_668_length_30461_cov_18.509735"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..974
                     /locus_tag="PK063_11460"
     CDS             <1..974
                     /locus_tag="PK063_11460"
                     /inference="COORDINATES: protein motif:HMM:TIGR03696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="RHS repeat-associated core domain-containing
                     protein"
                     /protein_id="HMZ97714.1"
                     /translation="DVTAATATGTLAVDLIDTGGIGGNAPLYLVTRDQATNQVLESRL
                     LFPARATFASTTPLGTPLVVASATVPTTTPVADGTLYYHQDGLGTVTELTDINGSVAK
                     AYAYDAYGNILESPGTVEQPYTYTGREFDQETGLYYYRARYYDAATGRFLQNDPIGFR
                     GGDVNLYRYVSNNPIYFSDPVGLQNTAVFPGTAAGSAAQGTSAGVKGALQGIGLGLGT
                     VAGAITGVTIFPDSAGEGSDIIPLPDTYPDTLLPEDDTVPDILLPPYIDIDTEIACPV
                     DPLQYSPHKKKRPSTYDKHTKPRPGRPTEKKKQQPGWKPFNDNKRRP"
     gene            1075..1707
                     /locus_tag="PK063_11465"
     CDS             1075..1707
                     /locus_tag="PK063_11465"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97715.1"
                     /translation="MLNDYVVSARSLRDLKKRAVNLGKRESHRIAVDTKMSCEYLGLY
                     DTYYVCGPLKSGALLGYTSTWGIKQKTLLPMMNEIRIRKALSGSSKGAYVIDAVYVIG
                     SQKPPIFKRRIIEAALLVEHDGKKDILEVAGRLANSPHVKRKITRDLRRQVLPEELEI
                     AGFSSIRRWASPSVGLGRCFKCNVKRYAKEFMISRLLHEEKKLVFPKPLR"
     gene            2124..3296
                     /locus_tag="PK063_11470"
     CDS             2124..3296
                     /locus_tag="PK063_11470"
                     /inference="COORDINATES: protein motif:HMM:TIGR03696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat-associated core domain-containing
                     protein"
                     /protein_id="HMZ97716.1"
                     /translation="MSRTPMVPGLGSGQTAVLASTPDGLRGPVVDDGIKVNGQVSVGF
                     VFVSGMPAPAIGQPIDSTGLEQPIAPIDVTAATATGTLAVDLIDTGGIGGNAPLYLVT
                     RDQATNQVLESRLLFPARATFASTTPLGTPLVVASATVPTTTPVADGTLYYHQDGLGT
                     VTELTDINGSVAKAYAYDAYGNILESPGTVEQPYTYTGRELDAESGLYYYRARYYDAQ
                     IGKFTQRDPIGRVGGNNYYEYALGNPTLHFDPFGLKAQIVIWAPVGIGTSSFGHVSTN
                     INGTTYSFGPNGMTNEPTSVFNQRNSFRSSLGLDLTLTAEQEKALEECLKRDQPDYNF
                     LTNNCGAPVQRCLNWMGYDIGKVLTPSQLYESMTGVGLVGGTIFYPGAGTKPAQAK"
     gene            3308..3664
                     /locus_tag="PK063_11475"
     CDS             3308..3664
                     /locus_tag="PK063_11475"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97717.1"
                     /translation="MAIKRLIGRGISVVLGVMILHVFMGCQGEELAEIDGDVNVLEHP
                     LPLRFSDPKTYTHPPDSLPINKVLVVLTKGQMVPVMRRIYGKEFLAYEIQLPDSSKGY
                     LFHGDAFHLVDSRRAP"
     gene            complement(4033..4848)
                     /gene="traT"
                     /locus_tag="PK063_11480"
     CDS             complement(4033..4848)
                     /gene="traT"
                     /locus_tag="PK063_11480"
                     /inference="COORDINATES: protein motif:HMM:NF017619.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="complement resistance protein TraT"
                     /protein_id="HMZ97718.1"
                     /translation="MSRINRRAHCSVGRTLAILSVVIATGSIVGCAGHMTLSHEVNLT
                     SSNAIFLTPSEEKTIYLQNRNTSDNPNINFAELPNKIKAKGYAIVDNPDKAQYILQSQ
                     VVLCNKLKPGQTVDALIAGGFGGAIGVAAGSAAALSGASLSQIPILGAVGAVGGFAAS
                     KFSEDSIVACVVDAMVQERTKEEIQQSVTTNSMPGPGTPQSQPGAFGFLNQQSVSPPQ
                     AGQVTQQISEIRKGTRRFHQARIVASDQKMWLSVPEASKILSDKLEDSLAGLF"
     gene            6077..7570
                     /locus_tag="PK063_11485"
     CDS             6077..7570
                     /locus_tag="PK063_11485"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ97719.1"
                     /translation="MVDQEKKYFEDVQELHQTDLKMRRIADAVPGAVYQYVITRDGCQ
                     RFSYISRGAMDMVGYPSDVIVSDYSAVWKLVLPEDMPGIMASIENAIRSGSRWAHEFR
                     LRLPDGRVKWLRGDSLPETPMVDGTVLFHGLLTDVTERRLAEAKLRFTQFATDHAADA
                     ILWAGPDRRIMYVNVRATELLGYSREELLNLSMPDIAPLQSRIDILNDLTRLKQGEVV
                     QYATTFRRKSGTVFPIEVSMRYLEHDGEGYVCAIVRDVSERKRAESVIQEGAEALRRS
                     QEALRALHSQLLTAQEDERRRVARELHDDLGSRLGSVILRAEGKLVLLENKSPEAAVI
                     KNVTDELRGISDRVRTIAHELHPSILDNLGLSVALKKMLKEYGSWSGMKIVSNISMEF
                     TEALDREVATCLYRIAQEALMNVKKHAGAQQVMVSLAREEGWVQLSVKDDGMGFSPET
                     ESRRTKGLGIVAMEERIHMVAGELAVQSGKGRGAVVVARAPYREREA"
     gene            7567..8286
                     /locus_tag="PK063_11490"
     CDS             7567..8286
                     /locus_tag="PK063_11490"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ97720.1"
                     /translation="MTTSVNSPINSPVKTISVVFADDHALVADGMTTILHGVNHKQRD
                     YEFAVVGQASSGRGLLELVKRVPADLAFVDISMPDMSGLDAVPKVREIRPDIKIIVVT
                     MHKEPEYMTRALSVGANGYLMKSCSAQEFCHAIDEVMRGNAYVTSLLGSRPTGALPGS
                     DDEEDQLASLGMSQRQREVVTLLASGKTIKETAFQLGLSRKTVEHHKAMFREKFGIET
                     DADLTKFAIKHGLTGTDWIQK"
     gene            complement(8610..10184)
                     /locus_tag="PK063_11495"
     CDS             complement(8610..10184)
                     /locus_tag="PK063_11495"
                     /inference="COORDINATES: protein motif:HMM:NF025085.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
                     /protein_id="HMZ97721.1"
                     /translation="MFSEDFYPTPGAVAAKMLQKIDRNAVHFLEPSAGKGDLAKAILG
                     FGRTRSPYDHGSRHRVDVIELHPDLLKILQAHEELTVVGYDWLTYDGVSYYDAIVMNP
                     PFSKGALHLLRAWDFLHNGEIVCLLNQETIDNPYTEDRQRLAAIIAAHGSVEPLGPCF
                     LTAERPTDTQVALVYLKKTTEDDRIHLWHSADREQSVNDDIGTPEAIPALRDTLGNMQ
                     HYYTQSLEEMFKAFAHIRKASLFMGALGTELRPSRSTRDESDLKKILGLAQTNTTAAR
                     AEFARALRRSAWMHVFEQMDFRKWLDTKQTEELLQDLERDSTVPFTTQNIKGTLSNIF
                     QQRKRLFEKSVWNVFLALTRHYKGNTTGDIGSGDGKAGWKSNDSYKVNCRLVFPYGCR
                     FWIGRFDLWSARDAGEIYSDLDRVLAVLDGQSFEEIVTVRDALERSFHNHGVHPHPCE
                     STFFRIRYFKKGTVHLKWKREDLLATFNTTAAAGRQWIGTTCHRDQDSQASYSHPDSN
                     DPHSWPSPVPTCQICA"
     gene            complement(10408..11463)
                     /locus_tag="PK063_11500"
     CDS             complement(10408..11463)
                     /locus_tag="PK063_11500"
                     /inference="COORDINATES: protein motif:HMM:NF024554.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HMZ97722.1"
                     /translation="MSISPDAIAHARSINLIEFLISRGHKPVSRRPHHADFHAPYRED
                     RNPSFSVSQRPDGTWVWYDFGRNEHEGCKQHGDLIDLVQLLDHVPFAEALHRILHNTV
                     RSMVAPSKPSTAPPTDKERIAHAKKLYYAAQANMTPEREEELRSYFHKLALPYNQHLG
                     AVWMRLGDDGIPYVAFPLPTPNIHFMQGLMARALGEAPPALMRVARGLKGPWILKRGN
                     APILITESIVDCLAGDELFGPSFTLCALNGLNTVERLQEYLKRLPSRIIYVALDNDAS
                     CIAVGNAPQNSSRKKGPHVQKELVSLLTHMGYHVMEVLLHHNASVKDLHKLWLKHPQR
                     VSLLDLAKTGLHHAPAC"
     gene            complement(11522..12433)
                     /locus_tag="PK063_11505"
     CDS             complement(11522..12433)
                     /locus_tag="PK063_11505"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97723.1"
                     /translation="MLNAQSAFSSLWSNAFCLMLTYRKLGIHRRMDSATVLSIDTEPS
                     RVRVTKSILSCPEYLAITRLYSRVRTKLEKLTLPAGLRSGMYLIPVSLASEVDTIIAN
                     AEDELRQLVDVFLAQYDKRIVEEESRLKAAYHTRDYPDPDTVRAAFGLTYSYITFDLP
                     GTLETISATMLKREERRSMEKVNNMLEDVNTYLREAMRSLVNHLVDRLSPSESGKSKT
                     FKSSTLTNLLEFLNTFDARNLGNDIELSQLVTTAKNVLSGVDSQLLRSDQSIANVVQN
                     GMGTIKAQLDSLLIKKPIRLYSFDEAA"
     gene            complement(12445..12648)
                     /locus_tag="PK063_11510"
     CDS             complement(12445..12648)
                     /locus_tag="PK063_11510"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97724.1"
                     /translation="MQTDSIRIKIEPDGTIKLITDEISLANHATAEDVIQQIITLSGG
                     SLQSSRRSTHNHHHHQADEHLHH"
     gene            complement(12670..12987)
                     /locus_tag="PK063_11515"
     CDS             complement(12670..12987)
                     /locus_tag="PK063_11515"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97725.1"
                     /translation="MPCYLEQRVSVELNMADVPLLISAGSSLGWEHTLNDDVLVFTTP
                     QNQQVSISKGRATLDQRHEALILELKQAYAQTIIQTAAEQFGWTLERVEGAEQELLLT
                     RFS"
     gene            complement(13022..14575)
                     /locus_tag="PK063_11520"
     CDS             complement(13022..14575)
                     /locus_tag="PK063_11520"
                     /inference="COORDINATES: protein motif:HMM:NF012234.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HMZ97726.1"
                     /translation="MSEQYPLAIDFRTARNVSVPLIAVNSLDPAATMRALAWSLVNVA
                     SASQADTDNEFGLHAFPILKWDIGHGLIPLNEEGKNWHTQNVGPSKQNTTINPAEALR
                     VLEKVPQRTLTFILNGHRYLSNDFFIQGLWNCRDLYKTNGSTIVLLGIGFKLPPELAN
                     DVVLLNEPLPTATQLESIVKEQLSAASLPLPDPATLAKAVDATLGLGAFTAEQEVARS
                     MQASGLNVDKLWERKRQIIDATPGLSVWRGGSSYAQIGGVATIKHFLKQVLVSKRAPR
                     CIVWLDEIEKSLSGSTGQASDTSGVSQALLGILLSYMQDHQASGLLLVGPNGTSKSAI
                     AKATGAEANIPTIALDISGLKSSLVGSSEQQMRQALNVISAISQDKACFIATSNNISQ
                     LPPELIRRFGYGTWYVDLPSQDEREAIWNIYFAKFGLAADTDRPNDHNWTGAEIERCA
                     RLSWELSMPLSEAAKYIVPTAISAKESIKALEAQAHQTYLSANREGVFDQNRDTPHHT
                     RPRTITLAQ"
     gene            complement(14668..14889)
                     /locus_tag="PK063_11525"
     CDS             complement(14668..14889)
                     /locus_tag="PK063_11525"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97727.1"
                     /translation="MSVPLPTPPHNIWLQRFKRLAQLTASLNSEDPRFPIIMTLLDKC
                     DRDYRTDNHASFIETGKRIRSLMDTPITS"
     gene            complement(14934..15644)
                     /locus_tag="PK063_11530"
     CDS             complement(14934..15644)
                     /locus_tag="PK063_11530"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97728.1"
                     /translation="MEITTKMLAQPRDNQDADRHALTPEPRQLVTARGTHRNLPNRRT
                     GYTQKATIGGHKLYIRTGEYEDGTLGEIFLDMHKEGAAFRSLMNCFAIAISLGLQYGV
                     PLEEFVESFTLMRFEPNGPVSGHDQIKMASSILDYIMRDLAINYLDRQDLAHVQVTHD
                     DLRGDSVKPYAKSTNHQTRQESSSLNTMASHPTNDIEEARIKGYEGDPCPECHRFTLV
                     RRGTCRTCSTCGSSTGCS"
     gene            15804..17213
                     /locus_tag="PK063_11535"
     CDS             15804..17213
                     /locus_tag="PK063_11535"
                     /inference="COORDINATES: protein motif:HMM:NF024108.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="HMZ97729.1"
                     /translation="MSEQGIEELRIRNRAGQRDPIVDGKVLVGYGACLQDPQRREGYL
                     VIRDEDRSGHVGIFGTTRIGKTRLMESILEQDIRSHKSVVAIDPKGDIDLFSKVVQVA
                     AEAGRLDEVMLVTPIFPDYSNYLDPLANYYMEDELVSHIVSGIKVKDDYYLSIASEVS
                     QVIVSGLIKLATSRGQVPTISFNDVNQRVGYTELINFRDVLKVLNDTEELCGLIDRVC
                     HGPGIAEHFAKVSSSLRTMLSALTFGNIGRIIGKARTNEFITRLEQGKRVILVCHTGS
                     LLSPRASLIFGRVFVSMIQSLVGRLFASGRQLDPPLCVHIDEGHNVLYPGIQEIFNKA
                     GGANVWLHFYEQSGAQMSAEIGADLARSISDNINSWIYFRVNHAETAQSVEDASPLVQ
                     RPRSVVSVQGNVTLHLNEERLVLRDRVLHLPKRCFYMRTHGQWYKGKTLDSSASYVQV
                     KFPTPAVNSPKSETPPSAA"
     gene            complement(17182..18297)
                     /locus_tag="PK063_11540"
     CDS             complement(17182..18297)
                     /locus_tag="PK063_11540"
                     /inference="COORDINATES: protein motif:HMM:NF024790.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HMZ97730.1"
                     /translation="MTFLIASFHVRLHYTWLIGFGLITWSLAANYFHDTQADLPVSYQ
                     WASGAIATLLILVSVFLHELAHAVTARRLGYAVKTIELHILGGWTIFERELSSPRVEI
                     LVALAGPGCSFLLTILLYALKADPLANFLYKVNLTLGAYNLFIPCLPMDGGRILRAVL
                     WTQTHSFAVATERTAQMSKQISSGMMAIGILGIIFQYQTLWLAIIGGILRMIAETAYR
                     TVQQSEQLTRPLQEVMIPRDRMVTLAHDTPLQELQDQFLRYGYRAYPTAEHGQITGLV
                     YYKDVRTDPKWLAPNGTTITPFIRNLSSDLIVHPVHTLQRALDAMLLSGSDQLLVFAG
                     ETCVGMVTRSMIARVQDAIGDPDSGPTLTRQREGFPI"
     gene            complement(18294..18824)
                     /locus_tag="PK063_11545"
     CDS             complement(18294..18824)
                     /locus_tag="PK063_11545"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97731.1"
                     /translation="MARVTWDTETKSLARGFYAIQITPVGRFGAVGECTFDAAVGDIV
                     EVKRGETKDREYRGFYLVVPKGYLILVAIADEVDDALKVVQYVAGQASPQDLAKGHWR
                     FESAASSWKGRTAPVDQPRMEPHPPRPVAQLPPIEKRQTKVTGEPASTAPRSSTTRSF
                     TRVRRHTPQPSKDEKE"
     gene            complement(18890..21001)
                     /locus_tag="PK063_11550"
     CDS             complement(18890..21001)
                     /locus_tag="PK063_11550"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: protein motif:HMM:NF024754.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HMZ97732.1"
                     /translation="MSIHDANTTSVVPLPLDPSLPMEDPSEPSSHTLPSQTLPDWLHA
                     RVQTPDNITQDRQITVSLDLATISPLIQNAQLNPEQLAVVTAPAEPTLVLAGAGSGKT
                     HTLIHRVAHLVTQGLPPDQILLITFTRKAAEEMIHRTQLLLQQHSLKIQGGTFHAMGL
                     IWLKHYGGALGLPPKFSIMDEDDAQGLVHLLMSKLSFSRRKGFPKKQHILALFSRAVN
                     TLRSIADTVSSDFPWLETHTPQLVVLFRAYTETKWRQHRVDYDDLLFLVYKLLCLHEP
                     TRRRLGTHYQAILVDEYQDTTKLQSEIIRLLGSHHHNVMVVGDDAQSIYGFRGAHTKN
                     MLEFQDAFPDVRLYKLEHNYRSTAPILTLANTVLHDAKALYPKRLFTTKHGGQPPELI
                     ACYSEQAQSDLLTERILQCRDEGIPFHRVAVLFRSSAHSNNLELTLARHKLAFVKYGG
                     LQLTETAHFKDVLAYLRAADNPLDSNAWHRLLLLLDRVGPKLAERLIATMQEAPHPLD
                     VLDHVPGKAESTIRLLNNVIRTTQDDTISLADRLTFVIKHYEPILKRDYPEDAKVRLE
                     DLKQLCYLARQSLTLEAFLEDLTLNPSTTPGTKHAHPEHHLVLSTIHSAKGLEWDVVF
                     VIWVLDGQFPPVRSWHDEDALEEERRLLYVAITRPRNQLFLTYPSEHYHNASQQNLDS
                     LCRFLAPIPDDILPGFAMDQV"
     gene            complement(21076..21690)
                     /locus_tag="PK063_11555"
     CDS             complement(21076..21690)
                     /locus_tag="PK063_11555"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97733.1"
                     /translation="MQCSSPESFASVDHAQPGEDHRSVLRTTLSKITLYNFAAAHSLD
                     TPIELTERLLLCILLANEDRHLSRTELHQITKINPSTIDSALLNLEQRNEVHTLPQHA
                     PEQTSYELTASGHTVAISLESWTTSFYQYAECGSDAGVRDLLHQLQRAIYSLIATNTI
                     PTTRACIACDFFAPESQTGGYCRFLSTPLTIQTTRPTASDTRTP"
     gene            complement(21811..23040)
                     /locus_tag="PK063_11560"
     CDS             complement(21811..23040)
                     /locus_tag="PK063_11560"
                     /inference="COORDINATES: protein motif:HMM:NF014273.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HMZ97734.1"
                     /translation="MESSADSPRSPVISSNGNFIVAGMSCPDVTFTESSLVTVSNKES
                     GMQIIMIPISQIRVHEEYATLFPPLTPTERESLKVSIQEAGIHDPLRVERQPTDIASA
                     QPYVVLAGHHRLSIAQELNIPEVPCIVVTTLELKVAALFDNIHRRQLSDTLRQQMQDE
                     EKRYRTKLRERLIPEILDVLPMLPPEVQLQLTQSNHDTQRDFLSKWMAQIQQVSIQRF
                     PEPQNNKFAAEEPDTSETPTPKGHKHLIRQINQLTKDFERQVAQQKKELEEVRQHNVS
                     LSRQLRAQTDEKEKLHEELQSLQRQLTSDDLDHKAERILKLQRKGRSQSLTIDEAGPL
                     ISGLLHTRKTIQLLQAFAQRIATLTTPDQTTILEHIKFTSQALGELEQVLPSPTASPL
                     HTPRQTLSVHKGLSADT"
     gene            complement(23421..24098)
                     /locus_tag="PK063_11565"
     CDS             complement(23421..24098)
                     /locus_tag="PK063_11565"
                     /inference="COORDINATES: protein motif:HMM:NF016430.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor"
                     /protein_id="HMZ97735.1"
                     /translation="MSFRTQAQQLAIDSDDTSPLLKLFQQSKPIIHSIAKRYCNLDRS
                     YEIEDLEQIGFLAVRKATEKWDFSRGNAQFQTFLYRYIQKAYQSEFDGRDKLVEITDK
                     DDQYVKTLPYSTFIKEKRRLHSQGFKSRIFRRLVPLATHEPPVSPDASPESLGLPDLP
                     NTDEVLAFTAIDRFIEFSRKRARTIPQPTALDHNLLTESEQTITRFSPDSGSSVRHAR
                     KRRNYAN"
     gene            complement(24121..24471)
                     /locus_tag="PK063_11570"
     CDS             complement(24121..24471)
                     /locus_tag="PK063_11570"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97736.1"
                     /translation="MNVTSHPVPEEAGELLALIQRELNLSTKAMSNQLGITDVWMRRL
                     LNNDIIPSQHLLKAIVTLYVNHPDPCTLNHRRDLAHRFTQACARTYYARNHHRLQQRC
                     HTLFHFPELTASLI"
     gene            24737..25411
                     /locus_tag="PK063_11575"
     CDS             24737..25411
                     /locus_tag="PK063_11575"
                     /inference="COORDINATES: protein motif:HMM:NF024949.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HMZ97737.1"
                     /translation="MVLVKDLLVRMRIAQNLTQTELAEKLGCTASHISIIEGGKSSGR
                     KKILPSDDMLRRIAQCLGGSPLDVQRRTYQLLLARAREVCSPEVAELLDDQILSGMPA
                     AFLERVRQDVSQYSDEELSRVTEQLQLGGRLKQVLSGIGRLSQAEVARLAQVLGQSSE
                     TYLVDAGYLSESARLLFGRNPNCVNILQIFGSLRPETQEELLRFGEASGSLSVTDGAR
                     LPASHE"
     gene            complement(25514..26848)
                     /locus_tag="PK063_11580"
     CDS             complement(25514..26848)
                     /locus_tag="PK063_11580"
                     /inference="COORDINATES: protein motif:HMM:NF039495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97738.1"
                     /translation="MSDADKPTFIPMNRINGISNRRRMPIIGKIRLGVKVSGPSGFYP
                     KETPHFVVPEEVAKVFGAQPKELEVMFVSNDPTVNCPQALRWYGESAGLQCIGNNQVA
                     RRLNQDTWKTESRSCPCEKLESGECGPRANLIFMIPKVSSGGLFQIDSSSINSMEKIN
                     SYFDFLALTLGRIAMIPLKLRRVPVTRRREGRPTTHYPLELRYEGSADETTRHQQETE
                     TVLRKIKMLEIQEPIEINPVLDPGAHVVMEEELEEDPSPIPAESVGEPGSETHNPAIP
                     PMSTPETAAAKAPEATHPPASPPISLAQTNYLLRLTKDLPLTEDEVRVKVRALTQREA
                     SGLIKKLLAEDFSFFTPSPNAPPATPVNTGSAADTMTDPQFKKIMGLVLSMGIPEPHV
                     KNLTAGYTKRQASTLIDQLVSGDFSAFQEMKEEELPILTTSGTVPGEEEPEF"
     gene            complement(26887..28023)
                     /locus_tag="PK063_11585"
     CDS             complement(26887..28023)
                     /locus_tag="PK063_11585"
                     /inference="COORDINATES: protein motif:HMM:NF024117.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HMZ97739.1"
                     /translation="MLAELIHPLALMEHQEWEYRPRPSNAGPDHCIRKLTYHARHAPA
                     KSPSGRFLVVLDDSTWHEELVLNWIAKSTFHLHSQQLELTCATTTFQGQPFPIKGHID
                     GVITDLLGIDRLLELKAVEHFTFTRYAEGNYPTNYLVQVVFYLVGLAALNPHIDEALL
                     LIKNKNQSAFLEYRVRYDRDNDRLTVLEITHSTGTRVYPHQDFVGLYQEALRRFEEVE
                     QYRDQDALPPRPYPNADNFHCAYCPYQFCWEGVDQVPIEGIAELRTGLVPAVEEYLDL
                     QTELAALTPKQKRLDALKQQFKLELRTEGITRAEGHGYYIASSPYEQSKLDQTKLSKA
                     TIERATVKETYSRFSAGRLSKVVDATKPKRRSPLKKPKPTTQIA"
     gene            28183..29970
                     /locus_tag="PK063_11590"
     CDS             28183..29970
                     /locus_tag="PK063_11590"
                     /inference="COORDINATES: protein motif:HMM:NF024991.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HMZ97740.1"
                     /translation="MVCSGSLEVRVQGEVVSAEMAGSPEEMPKVVGVITSRTRARRGS
                     GDWIEIARKHRAFIPDGLSVPSVGEVGECWGRVIANGPDPFLMVSRIRSRRFEACASS
                     SELLGVLGLRRSPPRQVVKVFQLLGPLVEWLCCAGWKAVARKLVKGTLRSVQAIAADP
                     FLLYRRRGLPFQAAVAAAQVLGHDLYSDEHYKAAVMEALAQADEEGIGGISDAHLVAR
                     CAELIGLPADRVASSITLQAGRAGKCEQGLWFSPGVYFVRKKALAMIRANQQDSGNAS
                     PSVQARALRYRYTVVTGGAGSGKTELARSLSAQVRERGGTVAATAMTGKAATLLGEDA
                     TTLHKLLGYGGGGYSVSSVGADLVLVDEAGMLTWHILYRLLLSCRGQIVLIGDPQQLA
                     PVGATPVMAELLTVLPVVHLGEEGSKGSLLVKVQVIRFASEALLLHQLRKVVCGYQDT
                     GVEWQALSPVYAGGLGVDRLNRLLQEIVNPDGLPCHGGFRTGDRVIVTKTRYDGGQRA
                     VNGEQGRVLGGMGDTIALRLDSGREVALRADELQLSYCITVHKAQGSRYQCVVFIIPE
                     RECGAFAVEERMQYVGRTRGREATVCMVY"
     gene            30028..>30461
                     /locus_tag="PK063_11595"
     CDS             30028..>30461
                     /locus_tag="PK063_11595"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97741.1"
                     /translation="MTLRAFGATVVKPMATRSLDRILTLEYHDTSPSGKNQMGLLVVD
                     GRIRRYPTKRFMRWLTNVEREFRTQLKGMQPYLPIQGECYAIVEYVPGDLITRDLPGM
                     QDAVWHMCERFGIVTNDKWFQHLIWITRPMDRADPRLSLRIVP"
BASE COUNT         6393 a         7094 c         9499 g         7475 t
ORIGIN      
        1 tcgatgtcac ggccgccacg gccaccggca ccctcgccgt ggacctgatc gatacggggg
       61 gcatcggcgg caatgctcca ctctatctgg tgacgcgcga ccaggccacg aaccaggtgc
      121 tcgagagccg cctgctgttt cccgcccgtg ccacgtttgc ctcgacgacg ccgctgggga
      181 caccgctcgt ggtggcctcg gcgacggtgc ccacgaccac accggtggcg gatggcacgc
      241 tgtactatca ccaggacggc ctcggtacgg tgacagaact caccgatatc aacggcagcg
      301 tcgccaaagc atatgcgtat gatgcgtacg ggaatattct ggagtcaccg ggtacggtgg
      361 agcagcccta tacgtatacg ggcagggagt tcgatcagga aacgggtctc tactactacc
      421 gggctagata ttatgatgcg gcgacggggc gtttcctgca gaacgatccg ataggtttca
      481 gaggagggga tgttaacctt taccggtatg tttcgaacaa ccctatctat ttcagcgatc
      541 cagtaggttt gcaaaataca gctgtgttcc ctgggactgc agctggttca gcggctcagg
      601 ggacaagcgc tggtgtgaaa ggagctttac aaggcatcgg gctaggtctt ggaactgtag
      661 ctggtgcaat aactggagta actatatttc ccgactccgc tggcgaggga tccgacataa
      721 ttcctcttcc tgatacctat cccgatactc tgcttcctga agacgatact gtaccagata
      781 ttcttctacc cccttatata gacatcgata cggagattgc atgcccagtt gacccacttc
      841 agtacagtcc gcataaaaag aagaggccat cgacttacga taagcatact aaacctcgac
      901 ctggacgacc gacagagaag aagaagcaac aaccaggttg gaagccattc aacgacaata
      961 agcggagacc ataatcgtgc aacgattgct ggcaattact aagggagctg aacttcaatg
     1021 ctagcgggaa taacccttct ctttaagtgt agatcgagga gtgcgctttt agggatgttg
     1081 aatgattatg ttgtttcagc gaggtccctt agggacctca agaagcgcgc agtaaatcta
     1141 ggcaaaagag agtcccatcg cattgctgtt gatacgaaaa tgagctgcga atatttgggg
     1201 ctttacgata catattatgt ctgtggacca ttaaagtcag gagccctact tggatatacg
     1261 agcacatggg gaatcaaaca aaagacactt cttccgatga tgaacgaaat tcgaatcagg
     1321 aaggcactct cgggaagctc taagggtgct tacgttattg atgccgtgta tgttatcggc
     1381 tctcaaaagc ctccaatctt caagcgaaga ataattgaag cagctctgct cgttgagcat
     1441 gacggcaaaa aagatattct tgaagtcgca ggtcgactag ctaactcccc acatgtaaag
     1501 cgcaagataa cgagagactt gagacgccag gttttacctg aagagttaga gatcgctggt
     1561 ttttcgagca ttcgcagatg ggcgagccct tctgtaggtt tagggaggtg ctttaagtgt
     1621 aatgtgaaac gctatgcgaa agaatttatg atcagcaggc ttcttcacga ggaaaagaag
     1681 ctggttttcc cgaaaccctt gaggtaacca tgtgcgttct ccgtctgata gtgaattggg
     1741 ctcctcctac gatcccgcca atcgggagac cgcaattagc cattagctca cgaccaccag
     1801 cagccagatc aacagggccg actatgtcta taatcccgtc ggcaatcgga ccagtctgac
     1861 ggatcgacgg ggcgcgcaga cgtttggcta tgaccggttg gaccgactca cctcagccag
     1921 ctaccccttg ctactcgatt cgcaagcgtt tgcctatgac gcggtgggga atcgcaccac
     1981 cggtggtgtt gtcgtgaacc cagggaatca actcacggcg gatactaacc atagctaccg
     2041 atggcgaaga cattctgctg gaatataatg gcagcaacgt gctgtaagca cgctataccc
     2101 acggccctgg catcgacgag cccttgagcc ggacgccgat ggtgccgggc ctcggcagcg
     2161 ggcagacggc tgtgctggct tccaccccgg acggcctgcg ggggccggtg gtggatgatg
     2221 ggatcaaggt gaacggccag gtgtcggtgg gctttgtctt cgtctccggg atgccggctc
     2281 cagcgatcgg gcagccaatc gactcaaccg gcctcgaaca gccgatcgcg ccgatcgatg
     2341 tcacggccgc cacggccacc ggcaccctcg ccgtggacct gatcgatacg gggggcatcg
     2401 gcggcaatgc tccactctat ctggtgacgc gcgaccaggc cacgaaccag gtgctcgaga
     2461 gccgcctgct gtttcccgcc cgtgccacgt ttgcctcgac gacgccgctg gggacaccgc
     2521 tcgtggtggc ctcggcgacg gtgcccacga ccacaccggt ggcggatggc acgctgtact
     2581 atcaccagga cggcctcggt acggtgacag aactcaccga tatcaacggc agcgtcgcca
     2641 aagcatatgc gtatgatgcg tacgggaata ttctggagtc accgggtacg gtggagcagc
     2701 cctatacgta tacgggaaga gagttggatg cagagtcagg gctctattac tatcgggcta
     2761 gatattatga tgcacagatt gggaaattca ctcaacgtga tcctattggt cgtgtcggag
     2821 gtaacaacta ctatgagtat gcccttggaa atccgacatt gcactttgat ccatttgggt
     2881 taaaggcaca gattgtgatt tgggctccgg tgggaattgg cacatcatcg tttggccatg
     2941 tgtccaccaa catcaatggc acaacctatt cattcgggcc aaatgggatg acgaacgagc
     3001 ccacttccgt atttaatcaa aggaactcgt tccggagttc gctggggttg gatttgaccc
     3061 tcacagccga acaggaaaag gcactggaag aatgtctcaa acgggaccaa cccgactata
     3121 actttctgac gaacaactgc ggtgcgccag tgcagagatg cctgaattgg atgggttacg
     3181 acattggtaa agtattaaca ccatcacagc tttacgaaag tatgactgga gttggtctcg
     3241 taggcggtac gatcttttat cccggagcgg gtaccaagcc tgctcaagct aaatagaggt
     3301 ttatgctatg gcgataaaaa ggttgatcgg tcggggcatt tcggttgttc taggggtgat
     3361 gattctccat gtcttcatgg ggtgccaagg tgaggagctg gccgaaatcg atggtgatgt
     3421 caatgtgcta gagcatccgt tgcctctaag gttttctgat cccaagacat atactcatcc
     3481 gccagattca cttcccatca ataaagtgct agttgtgctc acgaaagggc agatggttcc
     3541 agtcatgcga cgtatctatg ggaaagagtt tctggcatat gagatccaat tgcctgacag
     3601 tagtaaagga tatctgttcc atggtgatgc ctttcatctt gttgattcga gacgcgctcc
     3661 ataactgcaa ctgttcgagc ctgatatggg ctacacctat tatcccgcct cacaggtcac
     3721 cagcatcctg ctcaactcac cgcgaccagc agccagatca acaaggcgga ctatgtctac
     3781 aacccagtcg gcaatcgaac gagtctgacg gatcgccgag ggtcgcagac gtttggctat
     3841 gatcaattgg atcggctgat cattgcgagc catacgtggc tgcccgacgc tcaggcactt
     3901 gtctcttagg caatctcagc tagtgatgat ggccttcatc cacatgctca ccattttaat
     3961 cgtgcccgat ggtcaccctg ttcgtgactc ttgattccac gacgtacgcg ccctatcagg
     4021 gtcagtcatt ctttagaaaa gtccagctaa ggaatcctca agtttgtcac tgagtatctt
     4081 gctggcttcc ggaacggaca gccacatctt ttggtcagac gccacgattc tcgcttggtg
     4141 gaagcggcga gtgccttttc ggatttcgct gatctgttgg gtgacctgtc cagcttgagg
     4201 cggggagaca ctttgttgat tcagaaagcc aaaagctcca ggttgtgact gtggtgtgcc
     4261 tggccctggc atactattgg tcgtgacaga ttgttgaatt tcttccttgg tgcgctcctg
     4321 taccatcgcg tcgaccacgc aggcgacgat agagtcctct gagaatttgc tcgcggcaaa
     4381 tcccccaacc gctcctaccg ctccgagaat tggaatctgg ctaagcgacg ccccgctgag
     4441 tgctgcggcc gagccagctg cgactccgat ggccccaccg aacccgccgg cgatcaaggc
     4501 atcgacggtt tgcccgggct ttaatttatt gcagagtact acctggctct ggaggatgta
     4561 ctgagctttg tcgggattat caacgattgc atatcccttt gctttgatct tgttcgggag
     4621 ttcagcaaag ttgatattgg ggttgtcgct ggtgttgcga ttctggagat agattgtctt
     4681 ctcttccgac ggggttagaa agatggcgtt actgcttgtg agattcacct catgacttag
     4741 cgtcatgtgg ccagcacacc caacgatcga tcctgtggcg ataacgacac taaggatggc
     4801 gagagttctg ccgactgaac agtgggcgcg acggttaata cgtgacatgc cttcctcctg
     4861 ggtatgtgaa cgagtgtgaa ccgcttctgc tatgtattac tggatggcag tggatggtcc
     4921 ttggcgatac ccgtttgcgc cgtcgtcaca gagtggatga gaccgaacta gttgccatgt
     4981 gccaatatga gacaatcaga ccgaagggag tgtgtgtatg gaaaaaacca tgcgcaggaa
     5041 agctgggtat tgagtcacag agcgtgtttt tgtcatactg ccgcctgtgc ctgggacgag
     5101 tagtcgtaat acgtgtaatg tgcatagagt tggtgtgacg tccacgagcg attctctgac
     5161 ggcagagtga atcggagagc ggcctactga gttgtgagtt ggtgagaggg agttggaggg
     5221 tagtatgtcg ttgagcgtca aaggccaaga atcgacgttt gatctccgag agctctccct
     5281 cggtgatgcg tgtcgtttag gctcgtgggt acgagattta gagacagttg gaaaatcttc
     5341 cgaggaggtc tgtcaactca ttgcgatgtc tctggcccgg tctttctgtt cccaggagag
     5401 tcgtcagtct caattgtctc tcgtcgaggt ctttcacact cgtaatcttg gtgatctccc
     5461 agcgcgctac caagaccgat gggtgtcttc ggttgatggg gaccacgccc ccgctcaaac
     5521 gcgagtcctt gcattgatgg gcgtggccgg agattctgcg gagtggacga tcgacagacc
     5581 tccgttcgga ctacattgtg tccccattca agcggagttc agttcccagg aaactgcgtg
     5641 gtacacgcaa tcgtgggagg atttggggct gagcagtccg gtgaataatt ttgagaagag
     5701 tcttactgtc gccaattcac acaatcaatt gtttggaatc ctggtgcatg agattccacg
     5761 ctcttataac ctcgccgaaa gcagagcaga ctttctgcgg aggcatggag tgaaacaggt
     5821 tatttgcctg ggtgggctgc tgccttctgg agggagctac tgtgtcttcc tctactcgag
     5881 ggtgacagtc gattctagga tcagatcgtt gttgcaagtg ttatcaggca atatttgtct
     5941 ggcgtgttct actggggacg agcagtattg gagtgctaag gctaagagtg gtgaagggaa
     6001 gccgtactcc agagaggttg gattcgcatt tgctgaagag atttatcgcc ggctcttgaa
     6061 gctgaatgag tcgctcgtgg tcgatcagga gaagaagtat ttcgaggatg tccaagagtt
     6121 acaccagact gacctcaaga tgcgacggat tgcggatgct gtgcccggtg cggtgtatca
     6181 atatgttatt acgcgggatg gatgtcagcg gtttagctat atcagtcgtg gagccatgga
     6241 tatggtgggg tatccatcag acgtcattgt gtcagactat agtgcggtct ggaaattggt
     6301 cctaccagaa gatatgccgg ggatcatggc atccattgaa aacgcaatcc gcagtggatc
     6361 gcggtgggcg catgagttta ggttgcgact ccccgatggt cgcgtgaaat ggttgcgtgg
     6421 ggattctctg cctgagacgc ctatggtaga cggaacagta ctgttccacg gtttgttaac
     6481 cgatgtgact gagcgacggt tggctgaagc caagctgagg tttacgcagt ttgcgacgga
     6541 ccatgcggct gatgccattc tttgggctgg gcctgatcgt cgcatcatgt atgtgaatgt
     6601 acgggcaacc gagttgttgg gctattcacg cgaagaactc ttgaatttgt cgatgccgga
     6661 tattgctcct ttacagagcc gaatcgacat tcttaacgat ctgacgcggc tgaaacaggg
     6721 cgaagtagta cagtatgcga ctacattccg aagaaagtct ggaacggtct ttcccatcga
     6781 agtgtcgatg cgctacttgg agcatgatgg ggaagggtat gtgtgtgcca tcgtgcgaga
     6841 cgtgtcagag cgaaagcgtg ccgaaagtgt tattcaggag ggagctgagg ccctgcgtcg
     6901 cagccaagaa gcgttgaggg ccctccattc acagttgctg accgcgcaag aggacgaacg
     6961 acgcagggtt gccagggagt tgcatgatga tctgggatca cgattgggaa gtgtgatttt
     7021 gagggccgaa gggaaattgg tgttgttgga gaacaagagc cctgaggcgg cggtcatcaa
     7081 aaatgtcact gacgagctac gtggaatcag tgatcgggtg cgaacgattg cgcacgagtt
     7141 gcacccctcg atcttggata atcttgggct ctcggtggcg ctcaagaaaa tgttgaagga
     7201 gtatggcagt tggtcgggga tgaagatcgt cagtaatata tcgatggagt ttactgaggc
     7261 cttggatcgg gaggtcgcga cctgtcttta tcggattgct caggaagcct tgatgaacgt
     7321 gaagaaacac gctggtgcgc aacaggtcat ggtatccttg gctcgagaag agggttgggt
     7381 gcaactgagt gtgaaagatg atggaatggg gttcagtcca gagacagaat cgcgtcgaac
     7441 caagggacta gggattgtcg cgatggaaga gcgcatccac atggtggcag gggaattggc
     7501 ggttcagtca gggaaagggc gaggagctgt cgtagtggct cgggcacctt atagggagcg
     7561 tgaagcatga cgaccagtgt gaattctccg atcaactctc cggtaaaaac gattagcgtg
     7621 gtctttgctg acgaccatgc gttggtcgcg gatgggatga ctaccatttt acatggagtt
     7681 aaccataagc agcgtgacta tgaattcgcc gtggtgggcc aagcctcttc aggccgtgga
     7741 ttgctcgaac ttgtgaagcg ggttcctgcg gatttggcat ttgtcgatat ctcgatgccg
     7801 gatatgtctg gccttgatgc agttccgaag gttcgagaaa tcaggcctga cattaagatc
     7861 atcgtcgtga ccatgcacaa agaacctgaa tacatgactc gagcgttatc tgtgggggcg
     7921 aatgggtatc tgatgaagag ttgcagtgct caggagttct gccatgcgat cgatgaagtg
     7981 atgagaggca acgcgtatgt gacgagcctg cttggtagtc gtccgacagg ggctctgcct
     8041 ggttctgatg acgaagagga tcaactcgcc tccttgggga tgtcgcagcg gcagcgtgaa
     8101 gtcgtgacgt tgctggcgtc aggcaagacg atcaaagaga ctgcgtttca attgggtctg
     8161 agtcgaaaga ccgttgaaca ccacaaggca atgttcaggg agaaatttgg cattgagaca
     8221 gatgccgacc taaccaagtt cgcgatcaag catggtctga ccgggaccga ttggattcag
     8281 aagtaactac ccggctttgc tttcgggctt gggtggtggc gcttcgcagt cgatgatgag
     8341 gtgctggccg aagctctcac ccggggtgag gtcccatccc tggattacgg gtgtaaacct
     8401 ctctattgtc ctctccgttg ttctttcctc ccgttcattt gctctgtctg tgacttcgac
     8461 gatcggttcg agatcgacgc gtgtctttgt tgtggtgccc ttgattgccc agcgcttgtt
     8521 gtgctgttca agaatggtgt tattgacgag accgctggta acgtatccaa ggccgatcgg
     8581 cctttaggct tggagtctgg ggctactctc taggcgcaaa tctggcatgt tggtacgggc
     8641 gatggccagc tgtgggggtc gttactgtct ggatgagaat atgaagcttg ggagtcctga
     8701 tctctatggc aagtggtccc aatccactga cgtcctgcgg ctgcggtcgt gttgaaggtg
     8761 gccagcaggt cctctcgttt ccatttgaga tgcacggttc cctttttgaa atagcgtata
     8821 cgaaaaaagg tactctcaca ggggtggggg tgcaccccat gattgtgaaa tgagcgttcc
     8881 agcgcgtctc gcaccgtgac aatctcttcg aatgattgtc catctagcac ggcgaggacg
     8941 cgatccagat cggagtaaat ctcgccggcg tcacgggcag accagagatc gaatcgtccg
     9001 atccaaaatc gacagccgta tggaaacaca agccggcaat tgaccttgta cgagtcgttg
     9061 ctcttccagc ccgccttgcc gtccccgctc ccgatgtctc cggtggtgtt gcccttgtag
     9121 tgtcgtgtga gcgcgaggaa cacattccat accgatttct caaacaagcg tttgcgctgt
     9181 tggaatatat tggagagggt gcctttgatg ttctgtgtgg taaagggcac ggtgctatcg
     9241 cgttcaaggt cttgtaagag ttcttctgtc tgtttcgtat ctagccactt ccggaagtcc
     9301 atttgttcaa agacgtgcat ccaggcgctt cggcgaaggg cccgtgcgaa ttcggcgcgc
     9361 gcggcggtgg tgttggtttg ggccaagcca aggatctttt taagatcgga ctcgtctcgc
     9421 gtcgatcggc tcgggcgaag ctccgtgccg agtgcgccca taaagagact ggctttgcgg
     9481 atgtgggcga aggccttaaa catctcttct agggattgtg tgtagtagtg ctgcatattt
     9541 ccaagggtat cgcgaagcgc ggggatcgct tcaggtgtgc cgatgtcatc gttaacagat
     9601 tgttcgcggt cggccgaatg ccaaagatgg atgcgatcat cttccgtagt cttcttaagg
     9661 tagacgaggg cgacctgagt atcggtgggc cgttccgccg tgaggaagca ggggccaaga
     9721 ggttcgaccg agccatgtgc agcaataatc gcggccagcc gttgacggtc ttccgtgtaa
     9781 ggattatcga tggtctcttg attcaggagg cagacgattt cgccgttgtg cagaaaatcc
     9841 caagcgcgga gtagatggag ggcacctttg ctgaagggag gattcatcac aatggcgtcg
     9901 taataggaga cgccgtcgta ggtcaaccaa tcgtatccga cgacggttag ctcctcatgg
     9961 gcttggagga tcttcaagag atctgggtgg agttcgataa cgtcgacgcg atggcgtgaa
    10021 ccgtgatcgt agggagaccg agtccgaccg aatcccaata tggctttagc gagatcgcct
    10081 ttgccggcac tcggctcaag aaaatggaca gcattgcgat caattttctg aagcattttc
    10141 gctgcgacgg ccccgggcgt ggggtagaaa tcttcgctga acataccgct ccttttcgac
    10201 agacgcaggc aactgtgact tgaataggtt gacgctgttg gggattccgg agtgcggcac
    10261 tatctagggc ttcatcgaca cagtgtctac caggtaggtc acgccgtggt cattcagctc
    10321 ctgtggtcgt agtagtgggt gccataccgt gagtgtgacg gggtgtcaga ggtcacggac
    10381 gaggccatgg aatgtgacgc ggctgcgcta gcacgctggt gcatggtgga ggcccgtttt
    10441 tgccaaatcg agcagcgaca ctcgctgcgg atgcttcagc caaagcttgt gaagatcctt
    10501 tacgctggcg ttgtgatgga gtagcacttc cataacgtga tagcccatgt gagtcagcag
    10561 cgagaccagt tctttctgga cgtgtggccc cttctttcgt gagctgttct gaggcgcatt
    10621 tcccacggcg atacagcttg cgtcgttatc taacgcgaca tagatgattc gtgaggggag
    10681 ccgtttgaga tattcctgga ggcgctcaac cgtattcagc ccattcaggg cacagagggt
    10741 aaacgagggt ccgaagagct catcgcctgc aaggcaatcc acgatgcttt ccgtgatcag
    10801 aattggcgcg ttcccgcgtt taaggatcca ggggcccttg aggccgcggg cgacccgcat
    10861 cagggcgggt ggggcctcgc ccaaggctcg tgccatcagc ccttgcatga aatggatgtt
    10921 gggtgtggga agcgggaagg ctacgtatgg gatgccgtcg tcgcctagcc gcatccatac
    10981 agcgccaaga tgctggttgt aggggagcgc caatttatgg aaatacgacc ggagctcttc
    11041 ctcacgttcc ggggtcatgt tggcttgggc ggcatagtag agcttcttgg cgtgagcaat
    11101 acgctctttg tcggttgggg gggccgtgga gggtttgctc ggggccacca tactcctgac
    11161 ggtgttgtgc agaatccggt gcagggcttc tgcgaacggc acatggtcga ggagttggac
    11221 gaggtcgatg aggtctccgt gctgtttgca cccctcatgt tcgttgcgcc cgaagtcata
    11281 ccacacccag gtgccatccg gtcgctgcga gacagagaac gaaggatttc tatcttcacg
    11341 ataaggggcg tgaaaatctg catggtgcgg ccttctcgac accggtttgt ggccccgaga
    11401 gatgagaaac tcaatgaggt tgatactgcg ggcgtgggcg atggcgtctg gagaaatgga
    11461 catgtgcgtt atcagtaccg agaaagaggg tgtgtcgcgg tgaggggtct agttcgtaag
    11521 gttatgccgc ttcgtcgaag ctgtagaggc gtatcggctt cttgatgagg agggagtcca
    11581 gttgggcctt aatcgtaccc atcccgtttt gcacgacgtt agcgatcgat tgatcactgc
    11641 ggagcaattg cgagtctact ccactcagca cgtttttggc cgttgtgacg agttgagaga
    11701 gctcgatatc attacccaaa ttgcgcgcgt cgaaggtgtt caggaattcc aggagattgg
    11761 tgagcgtgct gctcttgaag gtcttggact tgccagattc actcggactt aaccgatcga
    11821 ccaggtggtt aacgagcgag cgcatggctt ctcggaggta ggtatttacg tcttcgagca
    11881 tattgttcac cttttccatt gaccggcgtt cttctcgttt aagcatcgtg gcactgatag
    11941 tctctagggt gccgggaaga tcaaacgtaa tataggagta ggtgagtccg aacgccgccc
    12001 gcacagtgtc tggatcgggg taatctctgg tgtgataggc cgccttgagg cgagactcct
    12061 cttccacaat acgtttatcg tattgcgcga gaaagacatc aacgagttgt cgtagctcgt
    12121 cttctgcgtt tgcaataatg gtgtcgacct ctgaggcgag cgagacagga atgaggtaca
    12181 tgcctgaacg aaggccggcc ggcagagtca acttttccaa tttggtgcgg acgcgggagt
    12241 acagtctcgt aatggccagg tattccggac aggacagaat ggatttagtc acacggacac
    12301 gactgggttc cgtatcaatg gagagcaccg tggcgctgtc catccgtcgg tgaatgccga
    12361 gttttcgata cgtgagcatg aggcagaatg cgttggacca cagtgaacta aatgccgatt
    12421 gagcattgag catgatgacc tcgcttagtg gtgaagatgt tcgtcggcct gatgatggtg
    12481 gtgattgtgt gttgagcgcc gactgctttg gagtgagccg cctgagagtg tgatgatctg
    12541 ttgtataacg tcttctgcag tggcgtggtt ggctaggctg atctcgtcgg taatcagttt
    12601 gatggttcca tctggttcaa tcttgatgcg tatgctgtcg gtctgcatgg aaaggtcact
    12661 ccagccgggt taggagaaac gagtgagcag taattcttgt tctgccccct caacgcgttc
    12721 taacgtccac ccgaattgtt cagcggccgt ctgaatgatg gtttgtgcat aggcttgctt
    12781 gagctccaga atcagggctt cgtgtcgctg gtccagcgtg gctcttcctt tcgaaatgga
    12841 gacttgctga ttttgtggag tggtgaagac caggacgtcg tcgttgaggg tgtgttccca
    12901 cccgagagaa gatcccgcgg agatgaggag ggggacatcg gccatattca actccaccga
    12961 gactctttgt tcgagatagc agggcatggc gtgttccttt tctctaggcg acagcgctgg
    13021 cttattgcgc cagggtaatg gtgcgaggac gtgtgtgatg cggcgtgtct cggttctggt
    13081 caaaaacgcc ctcacggttc gcactcagat aagtctgatg cgcctgtgct tcgagtgcct
    13141 tgatgctttc ctttgcactg atggccgtgg gaacgatgta cttggctgcc tcggacagtg
    13201 gcatagagag ttcccaactg agccgagcgc agcgctcgat ttctgcgcct gtccagttgt
    13261 gatcattcgg tcggtctgtg tcggcggcga gaccgaactt ggcgaagtag atgttccaga
    13321 tcgcctcgcg ctcatcctga ctggggagat ccacatacca ggtgccatag ccgaaccgac
    13381 ggatgagttc gggcggtagc tgactgatgt tgttggacgt ggcgataaag caggctttgt
    13441 cctgagagat agctgagatg acattcagcg cttgccgcat ctgttgttca cttgagccta
    13501 ccagtgagga cttgagacca gagatgtcta aggcgatggt ggggatgttc gcctcggctc
    13561 ccgtggcttt cgcaatggca ctcttcgagg tgccgttggg gccgacgagg agtaaacctg
    13621 aggcctggtg gtcctgcatg tagctcagaa gaatgccgag taaggcctga gagacgcctg
    13681 atgtatctga ggcttgtcca gtggatccgg agaggctttt ttcaatctcg tctagccaga
    13741 cgatgcagcg gggagcgcgt ttggagacca aaacctgttt gaggaagtgt ttgatggtag
    13801 cgactccccc gatttgcgcg tagctgctcc ctcctcgcca gacgctgagt cctggtgtcg
    13861 catcgatgat ctgtcgcttg cgttcccaca atttgtccac gttaagtccg ctcgcttgca
    13921 tggaccgagc gacttcctgt tcggcggtga aggccccaag gccaagcgtg gcatcgacgg
    13981 ccttggccaa tgtggcagga tcgggtaatg gcagcgatgc tgcagagagc tgctctttga
    14041 caatggattc cagctgtgtg gccgtcggga gcggctcgtt taggagcacc acgtcattgg
    14101 cgagctccgg tggcagttta aatccgatac ccaggaggac gatcgtactt ccgttcgtct
    14161 tgtagaggtc gcggcaattc cagaggcctt gaatgaagaa atcgtttgag aggtagcggt
    14221 gtccgttcag gatgaatgtc agtgtccgtt gcggcacctt ttcgaggacg cggagggctt
    14281 ctgcagggtt gatggtcgta ttttgcttgg agggcccgac attttgggta tgccagttct
    14341 taccctcctc attgagcggg atcaggccat gcccaatatc ccattttagt attgggaaag
    14401 catggaggcc gaattcgttg tcggtatcag cttgggaggc gctggcgaca ttgaccaatg
    14461 accaggcaag ggctcgcatg gtggcggctg ggtccagtga gttgacggca ataagcggca
    14521 cactgacgtt tctggcagta cgaaaatcga tggccagcgg gtattgttct gacatgtgga
    14581 tccttttggt ttcggagggt aagaggtcgt gatccatgaa atggtgttag aggcacgctg
    14641 gtggcgcggt cgtttctggg gtaggtatta gctggtgatt ggggtgtcca tgagggaacg
    14701 aatgcgtttg ccggtctcga taaacgaggc atggttgtct gtccggtagt cgcgatcaca
    14761 cttatcgagt agtgtcatga tgatggggaa gcgggggtct tcggaattga gcgaggcggt
    14821 caactgagca aggcgtttga accgttggag ccagatgttg tgtggagggg tgggcagtgg
    14881 gactgacata gaaactccgt gtgacctgag taaagggact ttcttagcta ggttcagctg
    14941 caacccgtgg agctcccgca tgttgagcat gttcgacacg tgccccgtcg gacgagagtg
    15001 aatcgatgac actctgggca cgggtcgccc tcgtagccct tgattcgggc ttcttcaatg
    15061 tcgtttgttg ggtgcgaggc catggtgttg agcgatgaag attcttgccg tgtttggtgg
    15121 tttgtggatt tggcataggg tttgacggag tctccccgga ggtcgtcatg agtaacctgg
    15181 acatgagcga ggtcctgtct gtcgaggtag ttgatcgcca gatcacgcat gatgtagtcg
    15241 aggatggacg aggccatctt gatttgatcg tgtcccgata ccggtccgtt aggttcgaag
    15301 cgcatcaacg tgaaggattc aacgaattct tcgagcggaa cgccgtattg cagtcctaag
    15361 gatatcgcga ttgcaaagca gttcatgaga ctacgaaatg cggcaccttc tttgtgcatg
    15421 tccaggaaga tttcccccag agttccgtct tcatactctc ctgtcctgat atagagcttg
    15481 tgcccgccta tcgtggcttt ctgggtatag cctgtccggc gattcggcag gttccgatgt
    15541 gttcctctgg ccgttacgag ctggcgcggc tcgggggtga gggcgtgtct atcggcatct
    15601 tggttatctc tgggctgggc caacattttt gtagtgatct ccatggctct ccgggttgtt
    15661 ctgatttcga cttagtcgat atctttgtat tactgatgtc taaatgagtg agggtgtggg
    15721 cggcagaagg agcttggata tgacctactc ctgtgtatgg ctgagacaat ggtctggtaa
    15781 tacacgatga gaagggggga gccatgtcgg aacaaggcat tgaggaattg aggatccgta
    15841 atcgagcagg gcagcgagat cccattgtgg acgggaaggt cttggtggga tatggcgcat
    15901 gtttgcagga ccctcagcga agagaaggat accttgtgat ccgagatgag gatcgttctg
    15961 ggcatgtggg gatttttggg acgacccgta tcgggaaaac gcgattgatg gagtccatcc
    16021 tcgagcagga catccggagt cacaaatcgg tggttgcaat cgatcccaaa ggggacatcg
    16081 acctcttttc aaaggtcgtg caggtcgctg cagaggccgg gaggctggat gaagtgatgc
    16141 tggtgacgcc gatctttcca gactactcca actatctcga tccgttggcg aattactata
    16201 tggaagatga gttggtcagc catatcgtct cagggatcaa ggtgaaggat gactactacc
    16261 tctccattgc gtctgaggtt tcccaggtga tcgtctcggg actaatcaaa ctcgcgacaa
    16321 gtcgagggca agtcccgacc atctccttca acgatgtcaa tcaacgggtg ggctacactg
    16381 aattgatcaa tttccgagat gtcttaaagg ttctgaatga tacggaggag ctgtgcggct
    16441 tgattgatag agtgtgccat ggtcccggca tcgcggagca tttcgccaag gtgtcgtcgt
    16501 cccttcgcac gatgctgagc gcgctgactt ttgggaatat tggtcggatt attgggaagg
    16561 cgcgaaccaa tgaattcatc actcgtctgg agcagggcaa gcgggtcatc ctggtatgtc
    16621 atactgggtc attgttgagt cctcgcgcgt ccctcatttt cggacgggtg tttgtgtcta
    16681 tgattcaaag tctcgttgga cgtcttttcg cgtccggccg tcagttggat cctccgttgt
    16741 gcgtgcatat cgacgaaggg cataacgtgc tgtatccggg gattcaagaa attttcaata
    16801 aggccggcgg ggcaaacgtt tggctgcact tctatgagca atcaggtgcg caaatgtcgg
    16861 ctgagattgg ggcggatctg gcccgaagta tcagcgacaa tatcaacagc tggatctatt
    16921 ttcgagtcaa tcatgctgag acggcgcaaa gtgttgagga tgcttccccg ctggtgcaac
    16981 ggccacggtc ggtcgtgtct gtgcaaggca acgtcacgtt gcatctgaat gaagaacgct
    17041 tggtgttgcg agaccgcgtg ttgcatttgc caaagcggtg tttttacatg cgtactcatg
    17101 ggcagtggta caaagggaag acgctggata gcagtgcgtc ctacgtccag gtgaagtttc
    17161 ctacacctgc ggtcaatagc cctaaatcgg aaacccctcc ctctgccgcg taagcgtagg
    17221 acccgagtcc ggatcgccga ttgcgtcttg gactcgggca atcatcgagc gtgtcaccat
    17281 tccgacacac gtctcacccg caaacaccaa cagttgatcc gaaccgctga ggagcatcgc
    17341 atcgagcgcc cgttgtaaag tgtgaaccgg gtgcacgatt agatctgagg acaagttgcg
    17401 aatgaacggg gtgatggtcg ttccgttcgg agcgagccac ttggggtcgg tgcgcacgtc
    17461 tttgtaatac accaagcctg tgatctgccc gtgttcggcg gtggggtaag ctcggtaccc
    17521 gtaacgaaga aactggtctt gcagctcttg taggggcgta tcgtgggcca gcgtcaccat
    17581 gcgatcccgc ggaatcatca cttcctgcag cggcctggtg agctgttcac tctgttgtac
    17641 ggtgcgataa gcggtctcgg cgatcatgcg gagaatgccg ccgataatcg caagccatag
    17701 cgtttggtac tgaaagatta tgcctagaat gccgatggcc atcatgccgc tgctgatttg
    17761 tttgctcatt tgagcggtac gttcagtggc gaccgcaaag gaatgggttt gagtccacaa
    17821 gactgcccgt aagatgcggc cgccgtccat tggcaggcag ggaatgaaga gattgtaggc
    17881 gccgagtgtg agattaactt tgtagaggaa gtttgccaga gggtctgcct tcagcgcata
    17941 gaggagaatg gtaaggagaa aggagcaacc tggacctgcg agggcgacca gaatttccac
    18001 ccgagggctt gagagttccc gctcaaaaat tgtccaacct ccgagaatgt gcaattcgat
    18061 ggtcttgacg gcgtacccga gtcgccgggc ggtgacggca tgggctagtt catgcaaaaa
    18121 aactgagacg agaatgagga gggtggcgat tgctccggac gcccactggt agctgacggg
    18181 gaggtcagcc tgcgtgtcgt gaaagtaatt ggctgcgaga ctccaggtga tgagaccaaa
    18241 tccgatgagc catgtgtaat ggagccgtac atggaaactg gcgatgagga acgtcattcc
    18301 ttctcatcct tgcttggctg gggtgtatgt ctgcgaaccc gtgtgaagga acgagtggtg
    18361 ctgcttcgag gtgcggtgga agctggctct cccgtgactt tagtctgtcg cttctcgatc
    18421 ggtggcaact gcgccacagg tcgcggggga tgtggttcca ttcgtggctg atcgacgggc
    18481 gccgttctgc ccttccacga gcttgcggca gattcgaacc gccaatgtcc ctttgcgagg
    18541 tcttgaggtg aagcctgccc ggccacgtat tggacgactt tgagggcgtc atcgacctca
    18601 tcggcaatcg cgacgaggat caagtatccc ttggggacga cgagatagaa gccgcgatat
    18661 tcccggtctt ttgtttcacc gcgtttcact tcaacaatgt ccccgaccgc ggcatcgaag
    18721 gtgcattcgc cgacggcccc aaaacgacct actggggtga tttgaatggc gtaaaaaccg
    18781 cgtgccagag atttggtctc ggtgtcccat gtcacgcgtg ccacaaaggg gcgatccttc
    18841 cgttcgcatt gggtgcggaa ctcgaaacgg aatatgcagg gagacttcat cagacttgat
    18901 ccatcgcgaa tccaggaaga atgtcgtctg ggatcggcgc gagaaaccga cagagcgagt
    18961 caaggttctg ctgagatgcg ttgtgatagt gctctgacgg atatgtgagg aagagctggt
    19021 tccgcggtcg cgtaatagct acataaagga ggcgtcgttc ttcttcaagg gcgtcctcgt
    19081 catgccaact tctgaccgga ggaaactgcc catcgaggac ccagataaca aagaccacat
    19141 cccactccaa acctttggcg ctatggattg tcgagagaac gaggtggtgt tctgggtggg
    19201 catgcttggt acccggtgtg gtcgaagggt tcaacgtgag gtcttccaag aatgcttcta
    19261 aggtgagtga ttgccgcgcg agatagcaga gttgcttcag atcttcgagc cggactttgg
    19321 catcttctgg ataatcgcgt ttaagaatcg gctcgtagtg tttgattacg aaggtgagac
    19381 gatcggctaa agaaatcgta tcgtcctgtg tcgtccggat aacgttattt aaaagccgga
    19441 tagttgattc cgccttgcca gggacatgat cgagcacgtc cagagggtgg ggggcctcct
    19501 gcatggtggc gatgagccgc tcggcgagct tcggcccgac gcgatcgagg agcaggagta
    19561 gccgatgcca ggcattgctg tcgagaggat tgtctgccgc gcggagatac gcgagcacgt
    19621 ctttgaagtg tgctgtttcg gttagctgga gaccaccata tttgacgaag gcaagcttat
    19681 gccgtgctag cgtcagttca aggttgttcg agtgggcaga ggagcgaaat aagaccgcca
    19741 cgcggtggaa gggaataccc tcgtcgcggc attgcaggat acgttccgtg agtaaatcgc
    19801 tttgcgcctg ttctgaataa caggcgatta gttccggtgg ctggccgccg tgtttcgtgg
    19861 tgaagagtcg tttcggatag agagcctttg catcatggag aacggtgttg gccagggtga
    19921 ggataggagc tgtgctgcga tagttgtgtt cgagtttgta gagccgcacg tcggggaagg
    19981 cgtcttgaaa ctccaacatg tttttcgtgt gggcaccgcg aaagccatag atactctggg
    20041 cgtcgtcacc gacgaccatc acgttgtgat ggtggctgcc caggagccta ataatctcgg
    20101 attggagttt ggtcgtgtcc tggtactcgt cgacaaggat ggcctgatag tgtgtcccga
    20161 gtctgcgacg ggtaggctca tggaggcaga gtaacttgta caccaggaaa agcaagtcgt
    20221 cgtagtccac gcgatgttgg cgccatttcg tttccgtata ggcacgaaac agaacgacga
    20281 gctgaggggt gtgtgtttca agccaaggga aatcgctgga gacggtatcc gcaatcgagc
    20341 gaagcgtatt cacggcccga ctaaagaggg ccagaatgtg ttgtttcttg ggaaaccctt
    20401 tccgacggga aaaagacagt ttgctcatca acaaatgcac cagtccctgc gcgtcgtctt
    20461 catccatgat gctgaacttg ggagggaggc ccagtgcgcc tccatagtgc tttagccata
    20521 tcaaccccat ggcgtggaag gtgccgcctt ggatcttcaa tgagtgttgc tggagaagga
    20581 gttgcgtcct gtggatcatt tcttctgcgg ctttgcgtgt aaatgtaatg agaaggattt
    20641 gatcgggggg aagcccttgg gtgacgaggt gtgcaacgcg atgaatgagc gtgtgggttt
    20701 taccgctgcc agcgccagcc aaaaccagtg tcggttcggc tggggctgtc accacggcga
    20761 gttgctctgg attgagttgc gcattctgaa tgaggggcga gatcgtggcg agatcaagcg
    20821 agacggttat ttgtcggtct tgggtgatgt tatccggtgt ctgaacgcgt gcgtgcagcc
    20881 agtctgggag tgtttgagac gggagtgtgt gggaggatgg ttcagacgga tcctccatcg
    20941 gcaacgacgg atcgagaggg agcgggacca cggatgtcgt gttggcgtca tggatagaca
    21001 tgaagtacct atgtgttacc ggaattggac ggagtgagga tttcgggaat tgatagacga
    21061 gggacgttgg tcgcgttagg gagtacgggt gtcagaagcg gtaggcctgg tcgtctggat
    21121 tgtgagtggc gtgctcagga accgacagta tccgcctgtt tgggactcag gcgcgaagaa
    21181 gtcgcaagca atgcatgccc gagttgttgg gattgtgttg gtcgcaataa ggctatagat
    21241 ggcccgttgg agttggtgga gcagatctcg taccccggca tctgatccac attccgcata
    21301 ctggtagaag ctggtggtcc acgattccag tgagatagct acagtgtgtc cggacgccgt
    21361 gagttcgtag ctggtctgtt caggggcgtg ctgcggtagc gtatgtactt cattgcgttg
    21421 ctcaagattg aggagagcgc tatcgatcgt ggatgggttg atcttggtaa tctggtgtag
    21481 ctcggtgcgc gagaggtgtc ggtcttcatt ggccaataag atgcacaaca ggagtcgttc
    21541 ggtcagttcg attggtgtat ccaaactgtg tgcggcggca aaattataca gagtgatttt
    21601 ggaaagtgtt gtgcggagca cagaccgatg atcttcgccc ggttgggcgt gatcgacgga
    21661 tgcgaacgat tcaggagagg aacactgcat gtgtagattc tccagtttcc acagttcagt
    21721 agtacaagta ttagatgact cggacaagtg gccaaatgcc tgttgcattg gggagctgac
    21781 ttggggattt ccccataagc ttacgtagca ctaggtatca gcagagagcc ccttgtgtac
    21841 tgacagcgtt tgtcgcggtg tgtggagcgg cgaggctgtg gggctcggga gcacttgttc
    21901 gagctctcct agggcctggc tagtgaactt gatatgttcg agaatcgtag tctgatcagg
    21961 ggtggtcaag gtggcaatgc gctgggcaaa ggcctgaagc aattggatgg ttttacgtgt
    22021 gtgcagcagc ccagaaatga gggggcctgc ctcgtcgatc gtcaggctct gggagcgacc
    22081 tttgcgctgt agtttgagaa tgcgctcggc cttgtggtcg agatcgtcgc tcgtcagttg
    22141 ccgttgaagg gactggagct cctcgtgtaa cttttccttc tcgtcagtct gtgcccgcag
    22201 ttgacgagaa agcgaaacgt tgtgttgtcg tacttcctct aattccttct tctgctgtgc
    22261 gacctgtctt tcaaaatcct tggtcagctg atttatctgg cggatcaggt gtttgtgccc
    22321 cttgggggtt ggtgtttccg aagtgtccgg ttcttctgcg gcgaatttgt tgttctgtgg
    22381 ttccgggaag cgctgaatgc tcacctgttg tatttgggcc atccactttg agaggaaatc
    22441 acgttgagta tcgtgattgg attgtgtgag ttggagttgc acttcaggag gcagcatggg
    22501 aagcacatcc aagatctctg gaatcagccg ttcccttagc ttggtgcggt agcgcttttc
    22561 ctcatcctgc atttgttggc ggagagtgtc cgacaattgg cgtcgatgga tgttatcgaa
    22621 cagcgcggcg accttcagtt ccaaggttgt cacaacgatg cagggcactt cggggatgtt
    22681 gagttcctgc gcgatgctca ggcggtggtg tcctgcgagt actacatagg gttgcgcgga
    22741 ggctatgtca gtgggttgtc gttcgactcg cagcggatcg tgaattccag cctcttggat
    22801 gctaactttc aggctctctc gctcggttgg ggtgagcggg ggaaagaggg tggcgtattc
    22861 ttcatggact cggatttgcg agatgggaat catgatgatc tgcatgccgg actccttgtt
    22921 gctgactgtg acgagcgatg attctgtaaa tgtgacgtcg ggacagctca tgcccgcgac
    22981 gatgaagttc ccgttggagc tgatgactgg tgatcgtggg ctgtcggcgg aggattccat
    23041 tggcaatttg ttgagcgctg gagtccggct cagcgaggtt ttttgtcagt ctacgttgga
    23101 ttgcaaagtt gcgatgaagc gcggacaaat agtgcagagg gaccacatat tgccgacctc
    23161 gatagcggcc ctgagacggg gtggtaacga tgtaccactg ggccggtgca tgctgaagaa
    23221 tggtttgcac gagccttggc agactatcgc gttccaaggt taaccaccga tagagcttcc
    23281 aatcactgca gggaatattg tgggcacggc aaatctccct gaacccgctc atgggcagaa
    23341 ctggctccat gggcatcgga gtaggccctg cgtggagccc cacctcccgg cagatggttt
    23401 ccgcgaggct tcgtgtcgta tcagttggca tagtttcgac gtttccgtgc atgacgaacg
    23461 gagctgccac tgtcaggaga gaatcgcgtg atggtctgct ccgactcggt caacaggttg
    23521 tgatcgaggg cggttggctg cggaatcgtc ctggcgcgtt tgcgagagaa ctcgatgaac
    23581 cgatcgatgg ccgtgaacgc cagcacctca tcggtgttgg gtagatcggg cagtcccagg
    23641 gattcaggcg aggcgtcagg ggatacgggc ggttcgtgag tcgccagagg aacaagcctt
    23701 cggaagatgc gacttttaaa gccctggctg tgtaagcgcc gcttttcttt gatgaatgtg
    23761 gaatagggca gcgtcttgac gtattggtcg tctttatctg tgatttcgac caatttgtcc
    23821 cggccatcaa attcgctttg gtatgctttc tggatatagc gatagaggaa ggtttggaat
    23881 tgggcgttgc cacgggaaaa atcccatttc tcagtggcct ttctgacggc cagaaatcct
    23941 atctgctcta aatcttcaat ttcataggag cgatctaaat tgcagtagcg cttcgcgatc
    24001 gagtggatga tgggtttgct ctgctgaaac agcttgagca gtggcgaagt atcgtctgag
    24061 tcgatggcga gttgttgagc ttgtgttcga aacgacatat ggttgtcctt tccgatgggg
    24121 ttagatgagt gaggccgtga gttccggaaa atgaaagagc gtgtggcaac gttgctggag
    24181 acgatgatgg ttccgtgcgt aatatgtgcg tgcgcaggct tgtgtgaatc tgtgcgccag
    24241 gtcccggcga tggttcagtg tgcagggatc gggatggttg acatagaggg tgacgatggc
    24301 tttcaggagg tgctgtgagg gaatgatgtc gttgttgagc agccggcgca tccagacgtc
    24361 ggtaatgccc aattgattgg acatcgcctt cgtactgagg ttgagttcgc gctggatgag
    24421 tgcgagaagt tctcccgctt cttcaggaac aggatgggac gtgacattca tgcggctgtc
    24481 ctttctcctt tggtgtaagt ggtgatgacc aacataaaca aatgtttgtt tgttcatcac
    24541 tgtgttactg ccctcgggaa tgtcagcagg actatacgca ggttttttgg ggtctgaaat
    24601 tgggaaggta gagtaatccc cataggcgta tggacaatag attggggttt tcctataatt
    24661 tgcgaacaag cgtttaatca cttcgcaagc gacggttgcg catctgtcta agtcttatcg
    24721 ggagagtgca gcgggtatgg tgctggtcaa agatttgtta gtccgcatgc ggattgccca
    24781 gaatctaact caaacggagt tggctgaaaa attggggtgt actgcctcgc acatatcgat
    24841 tattgaaggg ggaaagagca gcgggcggaa aaagattctc ccgagtgatg atatgttgcg
    24901 gcggattgcg cagtgcctag gtggatcccc gctcgatgtg caacggcgaa cgtatcaact
    24961 cctgctcgcc cgagctcggg aggtgtgttc gcccgaagtt gcagagcttt tagatgatca
    25021 gattctttcg ggtatgcctg ctgccttttt ggagcgggtc cggcaagacg tgagtcaata
    25081 ttcggacgag gagctttctc gggttacgga gcagctgcag ctgggtggac gattgaagca
    25141 ggtgctgtca ggtatcggtc ggttgagcca agcagaagtg gcgcgcttgg cccaggtctt
    25201 aggccaatcg tcggagacct acctggtgga tgccgggtat ctatctgaat ccgcgagatt
    25261 attgttcgga cgcaatccca actgtgtgaa tatccttcaa atatttgggt ctttacgccc
    25321 agaaacgcag gaagaattgt tgcgctttgg ggaggcgtcc ggaagtcttt cagtgacgga
    25381 tggcgcgcgc ctacctgctt cccatgagta agcgtgtccc ggaatatgtt gcgctcgtgt
    25441 cataagtgct caaggacggc cttgagccgc ccttgaggca ctctcacatt ccctttgcct
    25501 ggttgacagt ggcctagaac tccggttcct cctcccctgg tactgtccca gaagtggtaa
    25561 ggattggcag ttcctcctcc ttcatctcct ggaaggctga aaagtctcca ctaacaagtt
    25621 ggtcgatcag cgtcgaagct tgtcgtttcg tgtatcccgc agtcagattt ttcacgtgcg
    25681 gttctgggat acccatcgag aggacgaggc ccatgatttt cttaaactga ggatcggtca
    25741 tggtatcggc tgctgaccct gtgttcacag gcgtggccgg aggagcgttc gggctcggtg
    25801 tgaagaaaga aaagtcttca gcgaggagtt tcttgatgag tcccgacgct tcgcgctgtg
    25861 tgagtgcgcg gactttcacg cggacctcat cctctgtgag tggcaagtcc ttggttagcc
    25921 gaagcaggta gttggtctgg gccagtgaga tgggcggact tgctggtggg tgagtggcct
    25981 ccggcgcttt cgcggcggct gtctcgggcg tggacatcgg tgggatcgcc ggattgtgcg
    26041 tctcagaccc gggctctccc acggactctg ctggtatggg gctgggatct tcttctaact
    26101 cctcttccat gacgacgtgt gcgcctggat ccagaaccgg gttgatttca atcggctcct
    26161 gaatttccaa catcttgatc tttctcagga ccgtctccgt ttcctgttgg tgcctggtcg
    26221 tctcgtccgc tgagccttca tagcgcaatt cgagcggata atgagtggtc gggcgtcctt
    26281 cgcggcgtct agtgacgggc acgcgacgga gtttcagcgg gatcatggca atacgtccga
    26341 gggtgagcgc gaggaaatcg aaataggagt taatcttctc catcgagttg atactgctgg
    26401 aatcgatctg aaacaggccg ccgctgctga ctttcgggat catgaagatg agatttgcgc
    26461 gtggtccgca ttctccggac tcgagtttct cgcatggaca agatcgcgat tcagttttcc
    26521 aggtgtcttg attcaggcga cgagccacct gattgttccc aatgcattgt agtccggcgg
    26581 attctccata ccagcggaga gcttgcgggc agttgaccgt gggatcgttg gagacgaaca
    26641 tcacctccaa ctccttgggt tgcgccccga agaccttggc tacttcttct gggaccacga
    26701 aatgaggcgt ttccttgggg tagaacccgc tggggccgct cacttttacg ccgagacgga
    26761 tcttgccgat gataggcatg cggcgtcggt tagaaatgcc gttaatgcgg ttcatgggaa
    26821 tgaacgtggg tttgtctgcg tcggacatga tgcctcctag tcatgataat cagctgatga
    26881 atacagttac gcgatttgag tcgtcggttt aggctttttg agaggggacc ggcgtttcgg
    26941 tttggttgcg tcgacgactt tggacagtcg gcctgctgag aaacggctgt aagtttcctt
    27001 cacggtcgcg cgttcaatag tggctttaga gagtttggtt tgatccaatt tgctctgttc
    27061 atagggtgat gacgcgatgt agtagccatg cccctccgcg cgcgtgatcc cctcggtgcg
    27121 caattccaac ttaaattgct gctttagggc gtccagtcgc ttttgtttcg gagtgagcgc
    27181 tgcaagctca gtttgtaggt cgagatactc ctccacggcc ggcaccagcc cagtacgaag
    27241 ttccgcgatt ccctcaatgg ggacctggtc gaccccttcc cagcaaaact gatacggaca
    27301 gtaggcgcaa tggaagttgt cggcattggg gtacgggcgt gggggcaacg cgtcctgatc
    27361 acggtactgt tccacctctt caaagcgtcg gagtgcctct tgatacaagc ccacgaagtc
    27421 ttggtggggg tatacgcgtg tgcctgtact gtgggtgatt tccaggaccg tcaggcggtc
    27481 gttgtcccgg tcgtagcgga ctcgatattc aaggaatgcg ctttggttct tgtttttgat
    27541 gaggaggaga gcttcgtcga tatgaggatt cagtgcggcc aaaccaacca gatagaagac
    27601 cacttgtacg agatagttag tcgggtaatt cccttctgca tagcgagtga aggtgaagtg
    27661 ttcgacagcc tttaactcta gaaggcgatc aattcccaag aggtccgtga tgacgccgtc
    27721 aatgtggcct ttaattggga agggctgacc ctggaaggtc gtggtcgcgc aggtcagttc
    27781 aagctgctgg ctgtggagat gaaacgtgct cttagcaatc cagtttaaca ccagttcttc
    27841 gtgccaagta ctgtcgtcga ggacaacgag gaatcgaccg cttggacttt ttgcgggagc
    27901 atgccgggca tggtacgtga gtttgcggat gcagtggtct ggaccggcat tcgagggacg
    27961 aggccggtac tcccattcct gatgttccat gagagcgagt ggatgaatga gttcagcgag
    28021 catagggcct ccgggtgagt tcgtgcagcg cgtcgatcga ccgggaggtc gtgcggttcg
    28081 ctgaagtgaa cgagctgtga cataccgttt tggttccaaa acggtatgtc acagagttgc
    28141 agagatgagt gcgtgatggc tgaagcatgg ggagggagaa gcatggtctg ctctggatcc
    28201 ttagaagtgc gcgtgcaagg ggaggtcgtc tcagccgaga tggcgggcag tcctgaggaa
    28261 atgcctaagg tggttggggt gatcacgagt cggacccgtg cgcgccgtgg gtctggcgat
    28321 tggatcgaaa tagctcgtaa gcatcgggcg tttattccgg acggactgtc agtcccttcg
    28381 gtcggagagg tgggagagtg ctgggggcga gtgatagcca atgggcccga tccctttctg
    28441 atggtgtcca ggatacgatc acgacgattc gaagcctgcg cgagctcatc ggagttgttg
    28501 ggggtgctcg gcttgcgtcg ttcgccccca cgtcaggtcg tgaaggtgtt tcaattgttg
    28561 ggcccgctgg tggaatggct gtgttgtgca ggatggaaag ccgtggcgcg caaactcgtc
    28621 aagggaacgc tacgatcggt gcaggccatc gctgcagatc cgtttctact atatcgacgt
    28681 cgaggcctcc catttcaggc tgcggtggcg gccgcacagg tgttggggca cgacttgtat
    28741 agtgacgaac actataaggc cgcagtgatg gaggcccttg cacaagccga tgaagaaggg
    28801 atcggaggga tttctgacgc tcatcttgtg gcacggtgcg cagagctgat tggactgcct
    28861 gcggatcggg tagcgtcgtc aatcacactg caggcaggac gtgcggggaa atgcgagcag
    28921 ggcttgtggt tttccccagg ggtgtatttt gtgcggaaga aagccctggc catgattcga
    28981 gcgaatcagc aggactcagg taacgcgagt cccagcgtgc aagccagggc gttgcgctat
    29041 cggtatacgg tggttaccgg tggggctgga agtggaaaga ctgagctagc gaggtctctc
    29101 agtgctcagg tgcgtgagcg aggagggacg gtggcggcca cggcgatgac cgggaaagcg
    29161 gcgaccctcc tcggggaaga cgccacgacg ttgcacaagt tgctggggta tggaggcggc
    29221 ggctattcgg tgtcgagtgt gggtgccgac ttggtcttgg tcgatgaggc tggcatgctg
    29281 acctggcata tcctgtatcg attgttgttg agctgtcgcg ggcaaatcgt gttgatcggc
    29341 gatccgcagc aactagcccc ggtgggagcg actcctgtga tggcggagct gttgactgtc
    29401 ttgccggtgg tgcacttggg cgaagaagga tccaaggggt cgttgctggt caaggtccag
    29461 gtgattcgct tcgcatccga ggcgcttttg ctgcatcagt tgcggaaagt ggtgtgtggc
    29521 tatcaagaca ctggggtcga gtggcaggcg ttgtcccctg tgtacgcagg aggccttggt
    29581 gtggatcggt tgaaccgatt gctgcaggag attgtgaatc cggacggact gccatgtcac
    29641 ggtgggtttc gaacgggcga tcgcgtcatt gtcacgaaga ctcgatacga tggcggtcag
    29701 cgagcagtca atggtgagca agggcgggtg cttgggggaa tgggtgacac gatagcgttg
    29761 cgcctggact ctgggcgcga ggtagcactc agggcggatg agttgcagtt aagctattgc
    29821 attaccgtgc ataaagcgca ggggagtcgc taccagtgcg tggtgtttat cattccagag
    29881 cgggaatgtg gggcctttgc agtcgaggag cgcatgcaat atgttggcag aacacgtgga
    29941 cgtgaggcga cagtctgtat ggtgtattag cgtgggggct ggtgcatgag gcccggtcaa
    30001 tggcgaggtt cacagcaacg gaggcccatg accttgcgtg ctttcggagc cacagtggta
    30061 aagcccatgg cgacacggag cctggaccgt attctgacat tggaatatca cgatacgagt
    30121 ccgtcgggga agaatcagat ggggctgttg gttgtcgatg gccggattcg ccggtatcca
    30181 acgaagcgct tcatgcggtg gctgacgaat gtggaacggg agtttaggac tcagctaaag
    30241 gggatgcagc cgtacctacc gatccagggg gagtgttatg cgattgtgga gtatgtgccg
    30301 ggcgatctta tcacacggga tctcccgggg atgcaggatg cggtctggca tatgtgcgaa
    30361 cgatttggga ttgtcactaa cgacaagtgg tttcagcatc tgatctggat cacacggcca
    30421 atggatcgcg ctgatccacg gctctccttg cgaattgtgc c
//
LOCUS       DAOQPD010000046        29979 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_688_length_29979_cov_21.840563, whole genome shotgun sequence.
ACCESSION   DAOQPD010000046 DAOQPD010000000
VERSION     DAOQPD010000046.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 29979)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 29979)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29979
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_688_length_29979_cov_21.840563"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..739)
                     /locus_tag="PK063_11600"
     CDS             complement(<1..739)
                     /locus_tag="PK063_11600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proton-conducting transporter membrane subunit"
                     /protein_id="HMZ97742.1"
                     /translation="MMYALIPLLPLFSFLIVGIGEQWIKDRAHLVAVPAMVGSFLLSL
                     MALHDVATGQAVNVTLYTWLTSGNLDIHIGISIDRLTAVMLILVTTVSTLVHIYTIGY
                     MHGEPGYARFFAYIALFTFSMLMLVMADNLLQLFVFWEAVGLCSYLLIGHWYERASAC
                     AAATKAFLVNRVGDFGFILGLFLVWYSFGSLDYATVFAQAGQLASKTTNLLGPFGGTW
                     DVSVMTMICLLLFTGAVGKSAQVPLHVW"
     gene            complement(756..1061)
                     /gene="nuoK"
                     /locus_tag="PK063_11605"
     CDS             complement(756..1061)
                     /gene="nuoK"
                     /locus_tag="PK063_11605"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA];
                     GO_process: GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoK"
                     /protein_id="HMZ97743.1"
                     /translation="MTVPLSYYLVLSGFVFLTGVVGVLIRRNIIVILLSVELMLNATN
                     INFVAFSEYFHNVAGQVFVFFALTVAAAEVAVGLAIIIALHRTNSSIYIDDLNLLKR"
     gene            complement(1073..1588)
                     /locus_tag="PK063_11610"
     CDS             complement(1073..1588)
                     /locus_tag="PK063_11610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014960681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_function: GO:0048038 - quinone binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit J"
                     /protein_id="HMZ97744.1"
                     /translation="MDHIFFFYFAAVIATTSVLVVALRNPVYSALALLIMFFHVAGLY
                     VTLHAEFLAAVQIVVYAGAILVLYLFVVMLLSIKSEERYHNQLPVAGLLGVMLCTEII
                     LLLIQSRTAASTQAVPADPVTGSGNTEMVGEALYSTYLFPFEVASLILLVAMIGAIIL
                     AKKDINEQVQQ"
     gene            complement(1716..2291)
                     /gene="nuoI"
                     /locus_tag="PK063_11615"
     CDS             complement(1716..2291)
                     /gene="nuoI"
                     /locus_tag="PK063_11615"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoI"
                     /protein_id="HMZ97745.1"
                     /translation="MNVAITAQPKRKPSFSDWLKTLTFYELLVGMKATLKHLLNYKPI
                     TLQYPHEKRLLPENYRGMLALLRYDDGTEKCVGCDLCEAACPSRVIRVVSGEVPGEPT
                     KRYSKEYYMDMTRCLFCGLCVDACPVDALGMTREFEWAVYDKRQLHLNKQQLLAIGDR
                     AYPVREKRLELQHPNVAFFNVTFKHLPQKEN"
     gene            complement(2301..3368)
                     /gene="nuoH"
                     /locus_tag="PK063_11620"
     CDS             complement(2301..3368)
                     /gene="nuoH"
                     /locus_tag="PK063_11620"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoH"
                     /protein_id="HMZ97746.1"
                     /translation="MEIGLRLAVSLAQIAAVMGVVMLTVMILTLAERKVLGWMQDRMG
                     PMEVGPYGVLQPIADGLKLFFKEDIIPAGANKFLFTLAPILALVPAMIGFAVIPFGPT
                     MTIELFGMQVKPFVISDINIGILYILAFASIGAYGIILGGWSSNSKYSLLGGLRSAAQ
                     VISYELNVGLAIVGVILLSGSLSLVKITEAQAGGFWNWFIIAMPFPQIFAFVVYVISS
                     VAETNRVPFDLPEAESELVAGFFTEYSGMRFAFFFIAEYANMILVSCVAAALFLGGWN
                     APYPGTILGHLGLDALAWIENVVWFAAKVYFFLFLFFWLRATLPRLRYDQLMRFGWKV
                     MLPIALGNIVLTAIAAYFFPR"
     gene            complement(3393..6062)
                     /gene="nuoG"
                     /locus_tag="PK063_11625"
     CDS             complement(3393..6062)
                     /gene="nuoG"
                     /locus_tag="PK063_11625"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050136 - NADH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_process: GO:0006120 - mitochondrial electron transport,
                     NADH to ubiquinone [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoG"
                     /protein_id="HMZ97747.1"
                     /translation="MPDQKPETVRLTIDGTTVAVPKGTLVIEAARRVGVMIPHFCYHP
                     KLKPDANCRMCLVEVEKMPKLQTACSTPVAEGMAVRTATTTVDDAHKSVLEFILANHP
                     LDCPVCDQGGKCDLQDFSHQYTPTTSRFTETKRIFQKEYFSPLIETQMNRCVQCLRCV
                     RYCDEIMDVKALAPVGRGTMTEIKHFGPHELDCEFCGGCIQICPVGAITSRLSMYEYR
                     PWMLKRADTICTFCGDGCRITVQTKGNELIEVNSSHGAGRNNGDLCARGFFGFHASTH
                     ADRLTHPLIRRDGVLVQATWEDALEYVAEQALRVKLANGPDAFGGLISSRCTNEDLYV
                     FQKFMRQVIGTNRIDSSARYGHLSGVRALQRVQGTHRWTIAFEDIVAANALLLVGTNI
                     TETSPITGLKVKEAVKKRQASLVTIESLEPAVDTLSNIANLATQHFSAHPAQIGNNVL
                     GLIKAVIDGNLVDAGLAEQSPAFVQRLSAATQQISWDTLETATGHTRAQWAETAKLLA
                     AAKRVVILVGNGVLRHPGGEGTTTNLLDLLILLGKLNQPGCGLGPLAEENNDQGAVEM
                     GAVPEFLPGPAPLNDQAARDRLASLWREELPRTAGISLTEMLAAANSGSLKAMFVVGE
                     NPIGTLPTGAKAKEALGKLELLVCQELFLTETAAMAHVVLPACSYMEKDGTFTNSEGH
                     VQAVRQAINPIGDSRPDWEMLSAISVLMGSPLEYGDAREILKEIRSVIPGYGLLGPTP
                     TSPKVDQPILSRYLAEDASTDMASRYALRQAPKSSETSLTLLFTQTLFHSGKLSTHSK
                     GLLQLQQEGFLSLNPVDAAKVGVADGEKVTVSNARGSITTIAKIRERVPAGLVWFPEH
                     FDGEAKQLAEWTIDPRTQIPYFKLAHVSLAKVS"
     gene            complement(6099..7406)
                     /gene="nuoF"
                     /locus_tag="PK063_11630"
     CDS             complement(6099..7406)
                     /gene="nuoF"
                     /locus_tag="PK063_11630"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050136 - NADH dehydrogenase (quinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HMZ97748.1"
                     /translation="MKTYEPILLKNMIQPGYAGSLPEYERAGGYQALRKVLGKVTPAE
                     VTAVVMKSGLRGRGGAGFPTGVKWGFLPKDYQGPRYLCCNADESEPGTFKDRQLIERD
                     PHQLLEGMLLACYAIGAASSYIYIRGEFVLGAKILEAAIKEARAAGYVGKNILGTGVS
                     IDIWVHRGAGAYICGEETALLESLEGKRGLPRVKPPFPATHGLYNKPTVVNNVETLAN
                     LPHIMNRGAEWFASIGSPPKSTGTRVFCVSGHVARPGNYEVPMGITFRELIYEQAGGM
                     RSDKKLKAFIPGGASAPFLTPDHLDVKLDFESVALAGSMLGSGGVTVMEEGTDMVWAA
                     LRLMEFFYHESCGKCSPCREGSSWLVQIMRRIVNKRGRMEDLETLTDLCKNIAGRTVC
                     AFGDAEVSPILSTLKHWRHEYVTMIHAAEAANLIRPEPAGAKH"
     gene            complement(7473..8009)
                     /gene="nuoE"
                     /locus_tag="PK063_11635"
     CDS             complement(7473..8009)
                     /gene="nuoE"
                     /locus_tag="PK063_11635"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoE"
                     /protein_id="HMZ97749.1"
                     /translation="MLKEKYQAEIDEILSRYPVKRSALLPLLYLAQREEGYVTEAAMQ
                     EIAGILKLTPPQVYETATFYTMLNLKPVGKFHLQVCKSLMCALVGSDTVIGWIGTKLG
                     IKPGETTQDKLFTLSIVECLAACGTGPMMQVNDDYYERLTEEKLDRILADLRQTGTCS
                     LKTGPFMWPEPAAAKSGA"
     gene            complement(8130..9884)
                     /gene="nuoD"
                     /locus_tag="PK063_11640"
     CDS             complement(8130..9884)
                     /gene="nuoD"
                     /locus_tag="PK063_11640"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050136 - NADH dehydrogenase (quinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase (quinone) subunit D"
                     /protein_id="HMZ97750.1"
                     /translation="MQPLLERLMTTFPDAVRGVEVDAARNEVTARVSAARIVDVARWL
                     HDTPEAAFDHITDICSVDYPNDTERFEVIYQLLSLAHRRRIRLKVRITEDHPEVASVT
                     GIWKGADFMEREVYDLMGITFVGHPDLRRILLPEDYGEGHPLRKDFPAEGRGWRSEFP
                     FIPRLDEAPEELSAEGEIPESEKQVYRATEQPSSTRRREELLLNMGPQHPSTHGVLRV
                     VLELDGERIVKATPDLGYLHRGVEKLAEGLHYMQVIPHTDRLDYVCAMTNNYAYVRAV
                     EKLLDITVPERAEYIRTVVAEMQRIIGHLFWLGTQALDIGAMTVFFWTFREREILLDM
                     FEKLCGARLTLNYYRIGGVDSDFTPDLVTRLKAFLHTFPDKVNEYNQLLMSNRIWVGR
                     TKDIAVISAEDAINFGLTGPTLRGSGVDYDIRKYEPYGAYDKVEWEVPVGKRGDTYDR
                     YWVRMEEMRQSARIIAQCLDQMPEGPIMADVPHVIPPPKAKVMRDMESLIHHFIIFTQ
                     GFKPPKGETYCGTEVPKGELGFFIVSDGSPRPYRLKIRAPSFIHMGAFDHMARGYLIS
                     DIITIFGTYDIVMGECDR"
     gene            complement(9900..10379)
                     /locus_tag="PK063_11645"
     CDS             complement(9900..10379)
                     /locus_tag="PK063_11645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit B family
                     protein"
                     /protein_id="HMZ97751.1"
                     /translation="MSFLERQLDANILTTNLDAFVGWARKSSLWPMTFGLACCAIEMI
                     ASVSSRYDIDRFGAGVFRASPRQSDLMIVAGTVSRKMAPVIRRIYDQMAEPRYVISMG
                     SCATSGNHYNSYAVVQGVDQIVPVDVYIAGCPPRPEALIDGLLKLQQKIQREKIFVK"
     gene            complement(10477..10848)
                     /gene="ndhC"
                     /locus_tag="PK063_11650"
     CDS             complement(10477..10848)
                     /gene="ndhC"
                     /locus_tag="PK063_11650"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit A"
                     /protein_id="HMZ97752.1"
                     /translation="MGNEAAPLNYIPILIFIVIAFAFGAVQILLGRIVRPSRPYRAKL
                     APYESGSPLFSDAKIQFPIRYYIIAMLFVIFDIEIVFMFPWAVAFKKLGLVGLVEMVV
                     FIGILIVGFWYAWKKGALEWD"
     gene            complement(10924..12150)
                     /locus_tag="PK063_11655"
     CDS             complement(10924..12150)
                     /locus_tag="PK063_11655"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF014673.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HMZ97753.1"
                     /translation="MRWRLKRQSTTDKGGVTLSTGHPQLLAEIRAEIAAAGPIPFARF
                     MELALYHPQYGYYVRPVEDPTQERIGWSGDFYTSSDVHPILGQALAKQAQQLDACLGH
                     PNPFTVVEMGPGKGLLARDFLTACQNAPGNLSERLRYILIERSASMRALQHQHLAPWI
                     GRAGHVTWLDRLEDLPPDSVTGLFFSNELVDAFPVHRLAVVDGHPQEIYVDVHEEGFT
                     EIHRPLSEELSAYLQNGGIRLPDGYRTEINLKAVQWIKQVAQIMARGLVMTIDYGHTA
                     EDLYGPERKNGTFLCYYSQTTSEDAYERVGQQDMTAHVDFTTLAQAGQAAGLELTGFT
                     NQMSFLIGLGAEQFLESLQPESAEFYAAIHLLRPEGMGRTFKVLVQHTGMEKPELDGL
                     RFKPFFGSILAARSAA"
     gene            complement(12314..15019)
                     /gene="secA"
                     /locus_tag="PK063_11660"
     CDS             complement(12314..15019)
                     /gene="secA"
                     /locus_tag="PK063_11660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HMZ97754.1"
                     /translation="MLTQVLNIIFGSKNDREIKALRPIVEQINGLESSLTPLSDQALA
                     EKTQEFKKRLQDGETLEDILPEAFAVCREMSRRRLNMRHFDVQLIGGMILNKGRIAEM
                     KTGEGKTLVATLPLYLNALEGKGAHLVTVNDYLAKRDASWMAQLYHALGLTVGIIQHD
                     ASFLYDPTYEAADKRLQHLRPCSRHEAYRAEITYGTNNEYGFDYLRDNLIVSDLSQCV
                     QRPLHFAIVDEVDSILIDEARTPLIISGPTDQTTDLYYRINSIIPQLKPEHDYTIEEK
                     TKTASLTEEGNVRVEKLLGVDNLYDLQHMDLVHHVVKALQAYALYKRDVDYVVKDGEV
                     IIVDEFTGRLMPGRRWSDGLHQAVEAKEGVKIANENQTLASVTFQNYFRMYKKLAGMT
                     GTADTEAGEFAKIYNLDVNVVPTNRSMIRKDYADVVFRTEKEKFTAIVEEIKDCHERG
                     QPVLVGTISIEKSERLAGYLSRNGIKHNVLNAKFHEKEAEIIAQAGRKGAVTIATNMA
                     GRGTDILLGGNADFLFKRILYQDDTLTDARKQEIFDEIKADCEKDKQAVVAAGGLHIL
                     GTERHESRRIDNQLRGRAGRQGDPGSSRFYLSLEDDLMRIFASERVSQMMLKLGMEEG
                     VPIEHGMVTRAIANAQKKVEAHNFEVRKQLLEYDDVMNKQREVIYQHRHAVLAGEHIQ
                     QDIHDMMKDLVNAFVETYCPADQYQEEWDYNGLGEALQGQFALDITQGKGSVADHFKD
                     VGRDAMIEEIQTQVRRAYDHKEQELGSELMRYLEKMLLLQVIDHHWKDHLLGMDHLRD
                     GIGLRGYGQKDPLIEYKREGFDMFSSMMERIKSDVLERMFRVQAVRGEQPPPPAPEPI
                     PPPRMVLNRSDEPATQTVQSQGDKTGRNDPCPCGSGKKFKKCHGA"
     gene            15272..16354
                     /locus_tag="PK063_11665"
     CDS             15272..16354
                     /locus_tag="PK063_11665"
                     /inference="COORDINATES: protein motif:HMM:NF024299.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ97755.1"
                     /translation="MRQRVTGSRHLLTTLPLLCVALFVTSLPESSAASSASPESARRS
                     YERGVVLFREGNADGAIEALKKALAQNPKLAEAYHVLGLIYFQSKRNPDEAIQAYKQS
                     LKLSAPSAEILNDLADVYLAQGRGTDAEQVLRQVLDIAPGNEEAHLDLARLYEERHDR
                     TNAVKMYQSLLRIRPDHAEALYHLASLYDSQGDLKQAREYLSRLTQANPGHANAWYLL
                     GRLAERSNDLNAAAAAFKEAIAVKADLVDAHYNLGFVYRSQGLLVEAEREFLEVIRYR
                     PEYAEAHLNLGMVYTSLNRLDEAEREHERAVALKPTSAEAHYNLGVFYELHRKDMGRA
                     LAQYRRYRDLGGRDERVERIIGVGGP"
     gene            16414..16746
                     /locus_tag="PK063_11670"
     CDS             16414..16746
                     /locus_tag="PK063_11670"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97756.1"
                     /translation="MRARLWFFTMRSSRFHSLVWVVVFAVVALLAVTTGSAVAHELHH
                     AAHHDAGTHGSGICAWMCATAGVHVVTPVHATHVLALSGDASFLSDIVHLPQVSALCQ
                     SRAPPLSF"
     gene            16971..17423
                     /locus_tag="PK063_11675"
     CDS             16971..17423
                     /locus_tag="PK063_11675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97757.1"
                     /translation="MQVNQWLFRLGVCGLTGLVLSVSTPMVSAADTKAEKAFTIAVTD
                     AQGVETELKNGIFYWEEKMSETSFVPHELRHLPSKRGTATVNIKFDQIKQIELKPGAD
                     KTAPAMTVTLANGKSGEFVPAVSGSFKGESDFGQVEVPIGSLSKVVFK"
     gene            17459..18622
                     /locus_tag="PK063_11680"
     CDS             17459..18622
                     /locus_tag="PK063_11680"
                     /inference="COORDINATES: protein motif:HMM:TIGR01352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015291 - secondary active transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB family protein"
                     /protein_id="HMZ97758.1"
                     /translation="MDNVIVAHSGHSNQSVAGWGASLVFHACLALVALGLLPKMTVMV
                     EKEPFKWDVALVEPPREVARLEGPTPAPRVQPPTPTPVKPRSQPVRAVEPPPQPVQRQ
                     VETRVLPQAVQREVQPVVETVRPQEQIQSKQEVVQMQAKPVEPQEVHKTEPVVQAVAP
                     AEMQREVAAVVEQQVMEAAPATAQTYQAQQVVSAPAVVETVPEPVMTASAPVVHTPPA
                     VEAVPATAAPVDPAPAAESVAAAVSEPVAEPPAPVEAVVVPTAPVAAVTEPDPSTLRE
                     HQVVAQAAVARPAPKADYGWLADSLKRRVIELRHYPSTARLNGWEGKVVLKVSISNDG
                     QLKSVEVVKSSGHESLDQAAMEAVRRACPLHMKHELTAPMVVLNLPLVYSLNR"
     gene            18713..19225
                     /locus_tag="PK063_11685"
     CDS             18713..19225
                     /locus_tag="PK063_11685"
                     /inference="COORDINATES: protein motif:HMM:NF020123.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HMZ97759.1"
                     /translation="MTALLVSTLVGSALAMGSRPPAAGMPASGFSLTDLQGKAHTLEQ
                     YRGKIVLVNFWATWCKPCTSEMPAMQTVYDQLRDKDFVVLAVNELEDEAKVREHIQQY
                     KHTFPVLLDRENRVANQYGVFGLPVSVFIDQQGVVQEYIKGGLLTEQKIQEIVSRIQQ
                     AAPIKAAALH"
     gene            19257..19541
                     /locus_tag="PK063_11690"
     CDS             19257..19541
                     /locus_tag="PK063_11690"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97760.1"
                     /translation="MPLLLVCAFLALQGIAYPSMLEHVAQHAHHEAGVHGTVMCSWMC
                     AAGQDLEPVPEVAPVTISVIALLDEIVVDSVSIESRTLWPSRGPPSSSPA"
     gene            19660..20697
                     /locus_tag="PK063_11695"
     CDS             19660..20697
                     /locus_tag="PK063_11695"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97761.1"
                     /translation="MWAPSRRFLVSVLGIVAVAVVSVTSIPQAYAACGAVSCFVTIGS
                     QQQVPQSGLLTMNFIYSYTPMSLPSGSTGLIAEADQIGRRIIPNHHNERSTYTNSFAL
                     DFNYGVTDRLGLQVTLPYLTRRHEHYHFHQGQNEDLSRFSDKGLGDIRVMAKYNVLAS
                     LKNMVVFGVGTELPTGDYRQTDNLGGVLEPAGQLGRGQFGLVGTMYQSYEILPHRLNQ
                     FVFASYRHTFKNNDGYQFGDEYIVNGGFNLVTLPWLVFTAQVNYRYMTHDSLSASIGS
                     GPILDRGIPNTGSSWFGAAPGVLFNIGDTWQAYFYAQVPLYRDANNNLAQATSYTFGV
                     TKYFQLFTPGA"
     gene            20786..22060
                     /locus_tag="PK063_11700"
     CDS             20786..22060
                     /locus_tag="PK063_11700"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="sialidase family protein"
                     /protein_id="HMZ97762.1"
                     /translation="MPRRAKQALCAGLLFGLLPTMPTALAESPAGMQFGPKVTTEHKV
                     KSFVGPSVQIDEAGALSLAWMEENKEVRSVMYARSLEPGGPMGAPVRINRVEDIPYWR
                     QEAPALVVQGEDVFVTWGLAHPKATPEQPFATELRLSHSKDGGRTFQPSIVVNDDPGV
                     IQHTFDALHRDSEGRLHVSWIDGREGKKDPGTYVARSLDQGQTITKNAKVDEGTCVCC
                     RTAITSGPDGTVYVAWRKIFEGNVRETVVARSTDHGETFGSSVIVGHDKWVFPACPHR
                     PASMGVDWQGRLYIVWYTEGTDEIPAVYLAFSDDRGQTFSPKQQLNVSKNTFPDHPQI
                     AVDPEGRLVVIWEEQGPVKRDVVMSASTDRGATFTAPQKLNERKSQTPVVAVNRHGLF
                     AMAWMEHGMPGHKIVMQTLRMPSVTAAAAAGQ"
     gene            22078..22608
                     /locus_tag="PK063_11705"
     CDS             22078..22608
                     /locus_tag="PK063_11705"
                     /inference="COORDINATES: protein motif:HMM:NF020123.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HMZ97763.1"
                     /translation="MRLGFVQTFALFVAIGLWCDPALADDRLAALKVGRVAPGTVAAP
                     FELTSLDGAAVDLAQLKGKVVVVNFWATWCGPCKEEMPAFERLRRQLDPERFALMTIT
                     TDLQREGIKQFLANLHVQVSVLFDEDQAVSQAYLVRALPTTVVIDPQGMLIGRAVGPR
                     DWDAPNVVHALQSLMP"
     gene            22605..22925
                     /locus_tag="PK063_11710"
     CDS             22605..22925
                     /locus_tag="PK063_11710"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97764.1"
                     /translation="MMRVTKPSIGLAAALAGLYLVLAVFSVACVVDHADPKPAAHHHG
                     GTVSHSSFCAWACQANPTSDAGPVALFLQPFFVATLVVESSHAIVAGGVGFHTASRAP
                     PVQS"
     gene            23110..25377
                     /locus_tag="PK063_11715"
     CDS             23110..25377
                     /locus_tag="PK063_11715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HMZ97765.1"
                     /translation="MPSIAQEETAAGAVVEKSARERDLRDQLQNILRELEELQQQPAG
                     GAAAKPIQPAQPAAVEESSASVAAEPIPQYELSDVSIVSDRVQRRPEGLSMSSTEQSE
                     TEAQPTRTMKESMESLPGVVLRQANGPRDFSMMIRGQGAKTTFAVRDIKMYEDGFIQT
                     QSDGLSRLDIHDPWFMRSVEVTRGASSSLYDNYALGGMVHFRTRRGSDINGVETFLSG
                     GSFGYHKEGIAVGQQFENLDASLFVSNVGEDGFIRNSSYNTQTINLNLRFKIDDKQNF
                     YFKAITNWLDARVPTRLTQSQFNADHRQAGGTNVVCNANTCSDAERLAQRRLDRRTII
                     GGIYERQINANTVLTIEADYDVKDINQTFSQISDNVNPNYKHYADLRHDGRLFDMPLR
                     SYVGFFLSNMEQEAQTFQNLADGFGTRGALLQNSRGTIRNVGGRFREELEFIPKVTLA
                     AGLGFEQSQLSVQSIGYTGGAVSSRAGADRSYTNWAPEMSVTWKPTDAQRHWVRASTG
                     YGIPGFANLLRDPVTGQPGTNFDLKPQKNLNFEIGTESKLTKTLTVQLVGFWTFFKDE
                     IITQAVSGTNTASVNADSSQYKGIEAFYDWRPMEGLRLSGAYTHIEAKYVNFADRLNT
                     AAGFLTRDGNKVPNVPTDVLNTKVAYDHTATGWGAWVEGSYYNSYFLNNSNTFGIPSY
                     MIANVNVHKNFDLKNSWFRFAKFYVEVDNIADKKYAASGQVIGGETAGAAAGQQAFFA
                     GYGRAIYGGVTFGLF"
     gene            25443..25637
                     /locus_tag="PK063_11720"
     CDS             25443..25637
                     /locus_tag="PK063_11720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HMZ97766.1"
                     /translation="MNKQLLRVGEAADVLAVSRWTIYRWVEDGRLEGTKIGRGSLRVF
                     RASLDRLVQSNKTHEMNLSV"
     gene            25634..27076
                     /locus_tag="PK063_11725"
     CDS             25634..27076
                     /locus_tag="PK063_11725"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97767.1"
                     /translation="MTRIAVRSSSVVSARATSLVRLLLALVLIAMASGCAGGVGDPVP
                     PSLPQYAFINGQWFDGEGFRAATWYSVEGRLTKRPPAGLVQTVDLAGLYMVPPFGEAH
                     NHNVEGPWNVQAVAQRYLHDGVFYVKNPNDVRDFAQQIKHAINMPTSIDATFAHVGLT
                     GHGGHPAALYEDVLRIGRYEPAVGPIERGWFENRSYVVVETDAEVEAKWPVILRGSPD
                     FLKVYLVHSEDDGEEAKVKPAHHRKGLHPALVPGIVARAHAAGLQVTAHVETAADFRQ
                     AIRAGVDELAHVPGWLIQRADDAERARLTEEDARLAADHKVRVVTTSVAGQAMPSIGG
                     HHQHGSHAGHGTGQPMKHNALPADAASHVLKDNLHLLQREGVTLVIGSDHAETSLAEV
                     LHLSTLHLFDNRTLLKMWCEATPAAIFPARRIGKFAEGYEASFLALAGNPIEDFDQVQ
                     AIRRRFKQGVPLDGALMKDAAWSAAGQRSQ"
     gene            27152..29410
                     /locus_tag="PK063_11730"
     CDS             27152..29410
                     /locus_tag="PK063_11730"
                     /inference="COORDINATES: protein motif:HMM:NF012801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HMZ97768.1"
                     /translation="MKCSDRVGIIVIGLLAVALSGGIQPPAGLAAEESQEQEAPVIAV
                     EPVEVSGKRIENVEDVKREFARRPGSNILIQEKEITESRALNLQDVLQFAPGVRFQSR
                     FGADEGQFQIRGTSLRNNFHHRGINILINGIFFGDADGFSDFESIDLLAYERIEVYKG
                     ANALRYGANSIGGAINFVPRTGYSASTLQMRMLGGSFGMVSGQVSSGKVLQPFKVGNM
                     SATMDYYISVSGNRQDGFQDNSQQARERINANIGLQLGNHQEIRAYFLQANVAERIPG
                     SLTNQQLFFNRQQTGGQSPPGAPPFFACVSSNQACNWGRYYTLQRIGIAYHNEFAPNQ
                     FFEIIPYFSNQFVDHPIFQTIRQENNNVGGEFRYVNSNSLFGKNNSFVAGFQPRYGHQ
                     RQQRFVNINGNIGAMTQNYTAKTTYFGAYAEDAFDATKDFTIVIGGRWDYTGREATVD
                     NFGPAGNPFNPATPSVPTSTQKPLQHFGAISPKLGFVYRTTPTSQLYFNASRSYEAPL
                     NVELLSALNANGSANTGFLNLDAQRAWQLELGYRGTSADRRYSWDVTVYNLEMQKEIL
                     ASNINNTGTFQNANGTRHTGVEAGGAMVLKKGLFAQGGAGKEDSLQTRLAYTWSRFKF
                     TDDVRGGGIGGPNVLIAKDGNTVAGAPEHSLNVEARYDHPSGWWIAPNVEWSLSGFYT
                     DYNNTIKNPSYALINMRSGWNIDEHWTLFAEGRNLTNKTYAGAVVVNDSLNRFANPGF
                     GISAFGGVEYKF"
     gene            29619..>29979
                     /locus_tag="PK063_11735"
     CDS             29619..>29979
                     /locus_tag="PK063_11735"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97769.1"
                     /translation="MPAIYGLVTVLLLVWSMVPVYAEPGSTSPPTATFASLPRIESIQ
                     LSPSGRHLAVLRHHDGQTFLETHTVTGQDAHPVVSTDNREYIITWFRWINDERLLVSM
                     RFAATPEATDTVETRLMA"
BASE COUNT         6118 a         8471 c         9134 g         6256 t
ORIGIN      
        1 gccagacatg cagcgggact tgcgcggatt tgccgacggc tccggtaaag agcagaaggc
       61 agatcatcgt catcaccgaa acatcccagg tgccgccgaa cgggccgaga aggttcgttg
      121 tcttggacgc caattgccct gcttgcgcaa agaccgtggc atagtcgagc gagccgaagg
      181 agtaccagac gagaaacagg ccgaggatga acccaaaatc gccgacgcgg ttgacaagga
      241 aggccttcgt tgcggcagcg caggcgctcg cccgttcata ccaatggccg atcaggagat
      301 aggagcagag tccgaccgcc tcccagaaca cgaataactg cagcaggttg tccgccatca
      361 ccagcatcaa catcgagaag gtgaagaggg cgatataagc gaagaagcgg gcgtagccgg
      421 gctcgccatg catatagcca atcgtataga tgtgcaccag cgtgctgacg gtggtgacca
      481 ggatcagcat gacggcggtc aggcgatcga tggaaatgcc gatgtgaata tcgagattgc
      541 ccgaggtcag ccaggtgtaa agggtgacat tgacggcctg gccggtggcg acatcatgca
      601 aggccatgag cgacagtagg aacgagccca ccatagccgg aacggcgacg agatgcgcgc
      661 ggtccttgat ccactgttcg ccgatgccga cgatcagaaa ggagaacaag ggtagcaatg
      721 ggatcagcgc gtacatcatg gttggtacgt ttggtctacc gtttcaataa attcaagtcg
      781 tcgatataga tggacgaatt ggtccggtga agggcgataa tgatcgccag acccaccgcc
      841 acttccgccg ccgccacggt caaggcgaag aacacgaaga cctgtcccgc gacattgtga
      901 aaatattccg aaaaggccac gaagttgatg ttggtggcat tcagcatcag ctcgaccgac
      961 agcaagatca caatgatgtt ccgccggatc agcacgccca ccacgccggt gagaaacaca
     1021 aacccgctca ggaccagata gtaggataag ggaacagtca tgacagtacc ggttattgct
     1081 gaacctgttc gttgatatct tttttcgcca gaataatggc cccgatcatc gcgaccagca
     1141 ggatcaacga ggcgacttca aagggaaaca aataggttga gtacaaggct tccccgacca
     1201 tttccgtatt gcctgatccc gtgacggggt ccgcggggac cgcctgggtg gaagcagccg
     1261 tccgtgattg aatcagcaac aagatgattt ccgtgcacag catcacgccc aggagtcctg
     1321 cgacgggcag ttggttgtga tagcgctctt cggacttgat gctcaggagc atgacgacaa
     1381 acaggtagag caccagaatg gcgccggcat agacgacgat ctggactgcg gccaggaact
     1441 ccgcgtggag ggtcacgtac agtcccgcga catggaagaa catgatcagc aacgccagcg
     1501 cgctgtacac ggggttgcgc aaggcaacca ccagcacgga agtggtggcg atcaccgcag
     1561 caaaataaaa gaaaaaaatg tgatccatga gtccgttatc tcgtccgaat caactgaaac
     1621 cctgcccctg tcgccctggc tctctgcccg gtggcagcct gtttgcctcc ttcgtctctg
     1681 tgtggggggc cagcacggag gacgaggcgg aaggcctagt tctccttttg cgggagatgc
     1741 ttgaacgtca cgttaaaaaa cgccacgttc gggtgctgca gctcgaggcg cttttcccgg
     1801 acgggatagg cgcgatcgcc gatggcgagc agctgctgct tattgagatg gagttggcgc
     1861 ttgtcgtata ccgcccattc gaattcgcgg gtcatgccca gggcatccac gggacaggcg
     1921 tcgacgcaga ggccgcagaa gaggcatcgc gtcatatcca tgtagtattc cttggagtac
     1981 cgcttcgtcg gttctcccgg cacttcaccg ctgacgaccc ggatcacacg cgaggggcag
     2041 gcggcctcgc acaggtcgca gccgacgcac ttttccgttc cgtcgtcata ccgcaacaag
     2101 gccagcatcc cgcgataatt ctcgggtagg aggcgcttct catgcggata ctgtagcgtg
     2161 atcggcttgt aattgagtag gtgcttcagg gtggccttca tgcccacgag cagttcatag
     2221 aaggtcagcg ttttcagcca atcgctgaac gacggttttc gcttaggctg tgccgtgatg
     2281 gcgacgttca tctcgctccg ttaccgcggg aagaaatagg cggcgatggc cgtcaacaca
     2341 atgttgccga gggcgatggg caacatcacc ttccatccga accgcatgag ctggtcgtac
     2401 cgcaggcggg gcaatgtggc ccgcaaccag aagaacagga acaggaagaa gtagaccttt
     2461 gcggcgaacc agacgacgtt ttcgatccag gccagggcat ccagtccgag gtgcccgaga
     2521 atcgtgccgg ggtagggggc attccagccg cccaaaaaga gcgccgcggc gacgcaggac
     2581 accaggatca tgttcgcgta ttccgcaatg aagaaaaacg cgaagcgcat cccactgtat
     2641 tccgtgaaga agcccgccac cagttcgctt tccgcttcgg gaaggtcgaa gggcacacgg
     2701 ttcgtttccg ctaccgacga aatgacatag acgacgaaag caaaaatctg ggggaacggc
     2761 atggcgatga tgaaccagtt ccaaaaccct ccggcctgcg cctcggtgat cttcaccagg
     2821 ctcagcgagc cggacaggag gatgacgccc acgatcgcga gcccgacgtt caattcgtaa
     2881 ctgatgacct gcgcggcgga acgcagtccg ccgaggaggg aatacttgct gttggaggac
     2941 cagccgccga gaatgatgcc gtaggcgccg atagaggcaa aggccagaat atagagaatg
     3001 ccgatgttga tatcgctgat gacgaacggc ttgacctgca tgccgaacag ctcgatcgtc
     3061 atggtcgggc cgaatggaat gacagcaaac ccgatcatgg caggcaccag ggcgagaata
     3121 ggcgccaagg taaagaggaa cttgttcgcc ccggccggaa tgatgtcttc cttgaagaac
     3181 agtttcaatc cgtcggcgat cggttgaagc acgccgtagg ggccgacttc catcgggccc
     3241 atgcgatcct gcatccagcc gagcactttt cgctctgcga gggtcagaat catgacggtc
     3301 agcatcacca ctcccattac cgcggcgatt tgagctaacg acaccgccag tcgtaatccg
     3361 atttccataa cagcaatact cctcgtcccg tcctacgaga ccttcgccag agacacgtgc
     3421 gcgagcttaa aataggggat ttgagtccgg ggatcaatcg tccattcagc gagttgtttg
     3481 gcctcgccgt cgaaatgttc aggaaaccac accaggccgg ccggcacacg ctcgcgaatc
     3541 ttcgcgatgg tggtgatgga gccgcgtgcg ttcgagacgg tcactttttc gccgtccgcc
     3601 accccgactt tggccgcatc caccggattg agagacaaga acccctcctg ctgcaattgc
     3661 aggagtccct tggaatgggt ggacagtttg cctgagtgga acagggtctg agtgaacagc
     3721 agcgtcaacg acgtctcgct ggatttcggc gcctgtcgca gagcataccg gcttgccatg
     3781 tcggtcgagg cgtcttccgc cagatagcgg ctcagtatgg gctggtccac cttgggtgac
     3841 gtgggtgtcg gtcctagcag gccataacca gggatgacgc tgcgaatttc tttcagaatc
     3901 tcccgcgcat cgccatattc cagtggcgag cccatcaaga cggaaatcgc ggacaacatt
     3961 tcccaatcgg ggcgactgtc gccgatcgga ttgatcgcct gacgaacggc ttgcacatgc
     4021 ccctcggaat tggtgaaggt gccgtccttt tccatatagg agcaggcggg aagcactacg
     4081 tgggccatcg ctgctgtttc cgtgagaaag agttcctgac agaccagcag ttccagtttg
     4141 ccgagagcct ctttcgcctt cgccccggtc ggcaaggtgc caatcggatt ctctcccacc
     4201 acaaacatgg ccttcagaga gccgctattg gcggcggcaa gcatctcggt caacgagatg
     4261 ccggctgtgc ggggaagctc ctcgcgccac agcgatgcca gacggtccct cgcggcttgg
     4321 tcattgagcg gggccggtcc gggaaggaac tcaggcacgg cgcccatttc gactgcgcct
     4381 tgatcgttgt tttcttcggc cagcggtcca agtccgcacc caggttgatt gagtttgccc
     4441 agcaggatca ggagatccag gagattcgtg gtcgtgcctt ctccgccggg atggcgcagg
     4501 acgccgttgc ccacgaggat cacgacgcgt ttggccgcgg ccagaagttt ggcggtctcc
     4561 gcccattgtg cgcgggtatg gccggtggcg gtttcgagtg tgtcccagga aatctgttgc
     4621 gtagcggcgg atagccgttg cacgaaggcc ggcgattgct cagccaggcc tgcgtccacc
     4681 aggttgccat caatgacggc cttgatgagg cccaagacgt tattaccgat ctgcgcagga
     4741 tgggcagaga aatgttgcgt ggccaggttc gcgatattgc tcaatgtgtc gacggccggt
     4801 tccagcgact caatcgtgac cagactcgcc tggcgcttct tcacggcttc tttgaccttg
     4861 aggccggtaa tagggctggt ctccgtgatg ttggtgccga ccagcagtaa ggcgttggcg
     4921 gccacaatat cttcgaacgc gatggtccag cggtgggtcc cttgcacccg ttgtagtgct
     4981 cgcaccccgc tcagatggcc ataccgcgcg ctgctatcga ttcgattggt gccgatcacc
     5041 tgacgcatga acttctggaa tacgtaaagg tcttcgttgg tgcagcggga gctgatgagc
     5101 cctccgaacg catccgggcc gttggccagc ttcacccgga gggcctgttc ggcgacatat
     5161 tccaatgcgt cttcccacgt ggcttgcacc aagacgccgt cgcgtcggat caagggatgg
     5221 gtcaggcgat cggcatgggt gcttgcatgg aacccgaaga agccgcgggc gcagaggtcg
     5281 ccattgttcc gtccggcgcc gtgcgacgaa ttcacttcaa tgagttcgtt tcctttggtc
     5341 tggaccgtga tgcggcagcc gtcgccgcag aaggtgcaga tcgtatcggc ccgcttgagc
     5401 atccagggcc gatattcata catggacagc cggctcgtga tggcgccgac cgggcagatc
     5461 tggatgcagc cgccgcagaa ttcgcagtcg agttcatgcg ggccgaaatg tttgatttcc
     5521 gtcatcgtcc cgcggccgac gggcgccagg gccttgacgt ccatgatttc gtcgcaatag
     5581 cggacgcagc gcaaacactg cacgcaacgg ttcatctgcg tttcgatgag cgggctgaag
     5641 tactctttct gaaagatgcg cttggtttcc gtgaaccggc tggtcgtcgg tgtgtattga
     5701 tgcgagaagt cttgaaggtc gcacttgccg ccctggtcgc agaccggaca atcgagcgga
     5761 tggttcgcca gaatgaattc cagcaccgac ttgtgcgcat cgtccaccgt ggtggtggcg
     5821 gttcgcacgg ccatgccttc ggccaccggc gtgctgcagg cagtttgcag cttcggcatc
     5881 ttttcgactt cgaccaggca catgcggcag ttcgcatccg gcttcaactt ggggtgatag
     5941 cagaaatgcg gaatcatcac ccccacgcga cgcgcggctt caatcacgag cgtgcctttg
     6001 ggaacggcga cggtggtgcc gtcgatggtc agccgaacgg tttctggttt ttgatcaggc
     6061 atagtggccg ttattcgtgc aacgtgacac gagagacgtc aatgtttcgc tcctgccggt
     6121 tccggccgga tcaagttggc ggcctcagcc gcatgaatca tggtgacgta ctcgtgccgc
     6181 caatgtttga gtgtgctcaa aatcggagac acctcggcgt caccgaatgc gcagaccgtc
     6241 cgtccggcga tgtttttgca caggtcggtc agggtttcaa ggtcttccat ccgcccgcgt
     6301 ttgttgacga tccggcgcat gatctgaacg agccaggaac tgccttcccg gcagggactg
     6361 cacttgccgc aggactcgtg atagaaaaat tccatcaggc gcagggcagc ccagaccata
     6421 tcggtgccct cttccatgac cgtcacgccg cccgacccca gcatcgatcc ggccagcgcc
     6481 accgattcga aatccagctt gacgtccagg tgatcgggcg tgagaaaggg ggcggaagcg
     6541 cctcctggaa taaaggcctt gagtttcttg tccgaccgca tgccgccggc ctgttcatag
     6601 attaactcgc gaaacgtaat gcccatcggc acttcgtagt tgccgggtcg cgccacgtga
     6661 ccgctcacgc aaaagactcg tgtgccggtg cttttcggcg gagacccgat cgaggcaaac
     6721 cattcggcgc cgcgattcat gatatgcggc agattggcga gggtttcgac gttgttcacg
     6781 accgtcggtt tattgtagag accgtgcgtg gccgggaatg gcggcttgac gcgaggaaga
     6841 ccgcgtttgc cttccaacga ttccagcagg gccgtctctt caccgcaaat ataggcgccg
     6901 gctccgcgat ggacccagat gtcgatcgag acaccggtgc ccaggatatt cttgccgaca
     6961 tagcctgcgg cgcgcgcttc cttgatggcg gcttcgagaa tcttggctcc caggacaaac
     7021 tcaccgcgaa tatagatgta ggaactggct gcgccgatgg cgtagcaggc caacaacatg
     7081 ccttcgagca attgatgcgg atcgcgctca atcagctggc gatctttgaa cgtccccggc
     7141 tcgctctcgt cggcattgca acagaggtaa cggggcccct gataatcctt gggcaaaaat
     7201 ccccacttca cgccggttgg gaatccggct ccgccgcgtc cgcgcaatcc agacttcatg
     7261 acgacggcgg tcacctcggc gggggtgact tttcccagca ccttccgcaa cgcctggtat
     7321 ccgcccgcgc gctcatattc cggcagcgag ccggcatacc ccggctgaat catgttcttg
     7381 agcagaatcg gttcgtacgt tttcatacag gccatctcat ggaacgtgac acgcgagcag
     7441 tctcctttga gcgaatcgca aacgagggcg ggttaggccc ccgactttgc cgcggccggt
     7501 tccggccaca tgaacggccc ggttttcagc gagcaggtgc ctgtctgccg caaatccgcc
     7561 agaatgcggt ctaatttctc ttccgtcagt cgctcgtaat aatcgtcatt cacttgcatc
     7621 atcgggccgg tcccgcacgc ggccaggcat tcgacgatac tgagcgtgaa cagtttgtcc
     7681 tgggtcgttt cgcccggctt aatgccgagc ttggtgccga tccacccgat gacggtatct
     7741 gagccgacca gggcgcacat caacgatttg cagacctgca ggtggaactt tcccaccggc
     7801 ttcaggttca gcatcgtgta aaacgtggcc gtctcataca cctgcggcgg ggtcagcttc
     7861 aagatgcccg caatttcctg catggcggcc tcggtgacat aaccctcttc gcgctgcgcc
     7921 aagtagagca ggggcaagag cgcggatcgc ttcaccggat aacgagacag gatctcgtcg
     7981 atttccgcct gatatttttc tttcagcatc tctctcactc cacgctgcca gttacggtga
     8041 gttccacgtc gggggtactc ggtgcgtcca acgggggtct gctcagaccg cgcattccgc
     8101 gagcactccg gacacctggc tcatgcgcct catcggtcac attctcccat cacgatgtcg
     8161 taggtgccga agatcgtgat gatgtctgaa atcagatatc cgcgcgccat atggtcgaat
     8221 gcgcccatgt gaatgaagga gggggcgcga atcttgagcc gataggggcg ggggctgccg
     8281 tcgctgacga tgaaaaaccc gagctcgcct ttcgggactt cagtgccgca gtaggtttcg
     8341 cctttcggcg gcttgaaacc ctgggtgaaa ataataaagt ggtgaatcag gctctccatg
     8401 tcgcgcatga ccttcgcctt gggcggaggg atcacatgcg gcacatccgc catgatcggg
     8461 ccttccggca tctgatccag acactgggcg atgatccggg cactctgccg catttcctcc
     8521 atgcggaccc agtagcggtc gtaggtatcg ccccgcttgc cgacgggcac ttcccattcg
     8581 accttgtcgt aggcgccgta gggctcatac ttgcggatgt cgtagtcgac gccggacccg
     8641 cgcagtgtcg ggccggtgag gccgaaattg atggcgtctt cggctgagat caccgcgatg
     8701 tctttcgtgc gcccgaccca gatgcggttg gacatcagca gctgattgta ttcattgacc
     8761 ttgtccggaa acgtgtgcag gaaggccttc aggcgcgtga ccagatcggg cgtgaaatcg
     8821 ctgtcgactc cgccgatgcg gtaatagttc agcgtcagac gcgcgccgca caacttctcg
     8881 aacatgtcca gaaggatttc gcgctcgcga aacgtccaaa agaagacggt catggcgccg
     8941 atgtcgagcg cctgggtgcc gagccagaac agatggccga tgatgcgctg catctcggcg
     9001 acgacggtgc ggatatactc cgcccgttcc ggtaccgtga tgtcgagcag cttttccacg
     9061 gcgcgcacat aggcgtagtt attcgtcatc gcgcagacgt aatcgagccg gtcggtgtgg
     9121 gggatgacct gcatgtagtg gaggccttcc gccagctttt cgacgccgcg atggagatag
     9181 ccgagatcgg gagtggcttt gacgatccgc tcgccatcca gttccaacac cacccgtagc
     9241 acaccgtgtg tgctgggatg ctgggggccc atgttgagca ggagttcttc ccgccgccgt
     9301 gtgctgctcg gctgttcggt tgcccgatag acttgttttt ccgattcggg gatttctccc
     9361 tctgccgaca gttcttcggg ggcttcgtcc aaccgtggga tgaaggggaa ttcgctccgc
     9421 cagccgcgcc cttccgcggg aaaatctttc cgcaaagggt ggccttctcc atagtcttcc
     9481 ggcagcaaaa tgcgcctgag gtccgggtgc ccgacgaagg taatccccat caggtcgtag
     9541 acttcacgct ccatgaaatc cgcgcccttc caaatgccgg tcacggaggc gacttccgga
     9601 tggtcttcgg taatgcgcac tttgagtctg atgcgccgcc gatgtgcgag tgataacaac
     9661 tggtaaatga cttcaaaccg ttccgtatcg ttcggatagt ctaccgagca aatatcggtg
     9721 atgtgatcga acgcggcttc gggtgtgtcg tgcagccagc gcgcgacgtc gacgatccgc
     9781 gccgcggaca cacgcgcggt cacttcgttt cgagcggcat ccacctccac gccgcggacg
     9841 gcgtcgggaa aggtggtcat gagtcgttcg agcagcggtt gcatgatgaa aggagccggt
     9901 tactttacga aaatcttttc gcgctgaatt ttttgctgca actttaagag cccgtcgatc
     9961 aacgcctccg gtcgaggagg gcagccggca atatacacat cgaccggcac gatctggtcg
    10021 acgccctgta cgacggcata actgttgtaa tggttgccgg aggtcgcgca ggaccccatg
    10081 gaaatgacgt agcgcggctc ggccatctgg tcgtaaatgc gacgaatgac gggagccatc
    10141 ttccgggata ccgtgccggc cacgatcatg agatccgatt ggcggggcga ggcccggaac
    10201 acgccggcgc cgaaccgatc gatgtcatag cgtgaagaca cgctggcgat catttcgatg
    10261 gcgcaacagg ccaacccgaa cgtcatcggc cacaaggacg atttgcgcgc ccagccgacg
    10321 aaggcatcga gattcgtcgt cagaatattt gcatccagct gccgctctaa aaagctcata
    10381 tcaaccccgt gaaacgtgaa cggtgattcg tgaattggaa ggcaggaatc tattggcctg
    10441 catttctcac gtgtgccgcg tcacgtcgta cgccagtcag tcccactcca gcgcgccctt
    10501 tttccaggca taccagaacc cgacgatcag gatgccgata aacaccacca tctccactaa
    10561 ccctaccaac cccaacttct tgaatgccac ggcccaggga aacatgaaca cgatttcgat
    10621 atcaaagatc acgaacagca tcgcgatgat gtaatagcga atcggaaatt gtattttcgc
    10681 gtccgagaac aacgggctgc cgctttcata cggcgcgagc ttggcgcgat aaggccggct
    10741 cggccggacg atacgtccca acagaatctg cacagcgccg aacgcaaagg cgatcacgat
    10801 aaaaatcagg atcgggatgt aattcagcgg tgcggcttcg ttacccatgg tttgtccggg
    10861 aatcgtgaaa cgaaaaccct ctcacggcgg tcgtcacaat tagatggcgt cctgccggtt
    10921 cctttacgcg gcggaacgag ccgccaaaat cgatccgaag aacggcttga atctcaaccc
    10981 gtccagttcg ggcttctcca tgcccgtatg ttgcaccagc actttgaacg tccgccccat
    11041 tccttccggt cgcaggaggt ggatggcggc ataaaactcc gccgattccg gctgcagcga
    11101 ctccaggaac tgttcggcgc ccaggccgat cagaaaactc atttgattcg taaagccggt
    11161 caactcaagt ccggccgcct ggcctgcttg cgccagggtg gtgaagtcca catgcgccgt
    11221 catgtcctgc tggccgaccc gctcgtacgc gtcttccgag gtggtctgac tgtagtagca
    11281 gagaaatgtg ccgttcttgc gctccggtcc gtagaggtct tcggccgtgt gcccgtagtc
    11341 gatcgtcatc accaggccgc gtgccatgat ttgcgcgacc tgtttgatcc attgaacggc
    11401 cttgagattg atctcggttc ggtatccatc gggcagccgg atgccaccgt tttgcaaata
    11461 ggccgacagc tcttccgaaa ggggacgatg gatttccgtg aagccctctt cgtgaacatc
    11521 gacataaatc tcttgcggat ggccatccac caccgccagg cgatgcaccg ggaaagcatc
    11581 caccaattcg ttggaaaaga agaggccggt gacactgtcc ggcggaagat cttccaggcg
    11641 atcaagccag gtcacgtgac cggctcggcc gatccatggc gcgagatgct gatgctggag
    11701 ggcgcgcatt gaggcgctgc gttcaatcag gatgtaacgg agtcgttcgc tgagattgcc
    11761 gggcgcgttc tggcaggcgg tgagaaaatc ccgagccaac aatcctttgc ccggccccat
    11821 ctccaccacg gtgaacgggt ttggatgtcc caggcaggca tcgagttgct gcgcctgttt
    11881 ggccaatgcc tggccaagaa tcggatgcac atcggaactc gtatagaaat caccggacca
    11941 tccaatacgt tcctgggtcg gatcttcgac aggacgaacg taatagccgt attgcggatg
    12001 atacagggcc agctccatga aacgggcgaa gggaataggt cccgccgctg cgatttcagc
    12061 cctgatttcc gccaggagtt gtggatgccc agtgctcaaa gtgacaccac ccttgtcggt
    12121 agtcgactgc cgtttcaggc gccatcgcaa gaaaccgctc ttctaccgga ttctctaggg
    12181 aaaagagggg gttagattag ccgctggctc agcggcaagt caaggcgaaa agacccggaa
    12241 agacgcgagt ctctcgacat ttgcggaccg tttgtttctg ttcactccgc ggaggcgggc
    12301 caggaattcc cggctatgct ccgtgacact tcttgaattt ttttccgctt ccgcacgggc
    12361 agggatcgtt gcggccggtc ttgtcgccct ggctttggac ggtctgagtg gccggttcgt
    12421 cgctgcggtt caggaccatg cgcggcggag ggatcggttc gggtgccgga ggaggcggtt
    12481 gttcgccccg cacggcttgc acgcggaaca tgcgctccag cacatcggac ttgatgcgct
    12541 ccatcatgga ggagaacatg tcgaaccctt cgcgcttgta ctcgatcaac ggatctttct
    12601 ggccataccc gcgcaggccg atgccatccc gcaaatggtc catgcccagc aggtgatcct
    12661 tccagtgatg gtcgatcact tggagcagga gcattttttc gagataccgc atgagttcag
    12721 agcccagttc ctgttctttg tggtcatagg ctcgccgcac ctgggtctga atctcctcga
    12781 tcatcgcatc ccggccgacg tccttaaagt gatcggcgac actgcccttg ccctgggtga
    12841 tgtcgagggc gaactggccc tgcagcgctt ctccgagacc gttgtagtcc cactcttcct
    12901 ggtattgatc ggcgggacag taggtctcga cgaaggcatt caccagatcc ttcatcatgt
    12961 cgtgaatgtc ctgctggatg tgttcccccg ccaggacggc atgccggtgc tggtagatca
    13021 cttcccgctg cttgttcatg acatcgtcgt actcaaggag ctgcttgcgg acttcgaagt
    13081 tgtgcgcctc gacttttttc tgcgcgttcg cgatggcgcg ggtgaccatg ccatgttcga
    13141 tcgggacacc ttcctccatc ccgagcttga gcatcatctg cgagacgcgt tcggacgcga
    13201 agatccgcat gagatcgtct tcgagcgaca ggtagaagcg tgaagatccg ggatcgcctt
    13261 ggcggccggc ccgaccacga agctgattgt cgatgcgccg gctctcgtgc cgctcggtgc
    13321 cgaggatatg gagacctccg gccgcgacca cggcctgctt gtccttctcg caatcggctt
    13381 tgatttcgtc gaaaatttcc tgctttcgcg cgtctgtcag cgtgtcgtct tgatagagaa
    13441 tgcgcttgaa gaggaagtca gcattaccgc cgaggagaat gtccgttccg cggccggcca
    13501 tattggtggc gatggtcacg gcgcctttgc gaccggcctg ggcgatgatt tccgcttctt
    13561 tctcgtgaaa cttggcgttc aacacgttgt gcttgatgcc attgcggctc aagtagcccg
    13621 ccagacgctc agatttctcg atggaaatgg tgccgacgag gactggttgt ccgcgctcgt
    13681 ggcagtcttt gatttcttcg acgatggctg tgaacttttc tttttcggtg cggaagacga
    13741 cgtcggcgta gtctttgcgg atcatcgacc ggttggtcgg gaccacgttg acgtccagat
    13801 tgtagatctt ggcaaactcg cccgcttccg tatcggcggt gccggtcatg cccgccagtt
    13861 ttttgtacat ccggaaataa ttctggaagg tgaccgaggc cagggtttgg ttctcgttgg
    13921 cgatcttgac gccttctttg gcttccacgg cctggtgcag cccgtcgctc caccggcggc
    13981 cgggcatcaa gcgtccggta aattcgtcga cgatgatgac ttcgccatcc ttgaccacat
    14041 agtccacgtc acgcttgtag agggcatagg cctggagggc cttgacgacg tggtgtacca
    14101 gatccatgtg ctgcaggtcg tacaggttgt ccacgcctag cagtttctcc acgcggacgt
    14161 tgccctcttc cgtgagcgag gcggtcttgg ttttttcttc gatcgtgtag tcgtgctccg
    14221 gtttgagctg cggaatgatc gaattgatgc ggtagtacaa atccgtggtt tgatccgtcg
    14281 ggccggaaat gatcaagggc gtgcgcgcct cgtcgatcag aatgctgtcg acttcgtcca
    14341 cgatggcgaa gtgcagcggg cgctggacgc actggctcaa gtcgctgacg atcaaattgt
    14401 cgcggaggta atcgaagccg tattcgttat tggtgccgta ggtgatctcg gcgcgatagg
    14461 cttcatgccg gctgcagggg cggaggtgct ggaggcgttt gtccgccgcc tcgtaggtcg
    14521 gatcgtaaag aaaagaggca tcgtgctgga tgatgccgac cgtcaggccg agcgcatgat
    14581 agagctgggc catccaggag gcgtcgcgtt ttgccaggta gtcgttgacc gtgaccaggt
    14641 gggcgccctt cccctccagc gcattgagat acagggggag ggtggcgacc agggttttac
    14701 cttcaccggt cttcatttcg gcgatccggc ctttgttcag aatcatgccg ccgatcaact
    14761 gcacgtcgaa gtggcgcatg ttcaaacggc ggcgagacat ttcgcggcag acggcaaacg
    14821 cctcgggcag aatgtcctca agggtctcac cgtcctggag acgcttcttg aattcctgcg
    14881 ttttctccgc cagggcttga tcggacaggg gcgtgaggct tgattccagc ccgttgatct
    14941 gctcgacaat cgggcgcaat gccttgatct cacgatcgtt tttactgccg aatatgatgt
    15001 tcagaacttg ggtcagcatg cagacgtacc tttattctct cgaacctgcc gggagacgaa
    15061 gctcgcccct ctggcacggg ctcggcggcg gagtatacag gaatccgtca tcgaatccta
    15121 ccgaaacagg ggcgacggtc tcaactgttt cacgatgaac gactgcgaca ggtgctcgtc
    15181 gttgctttcg gatgcggtga catctatagt gggcccacca tctcgccggc tcttacggcg
    15241 aagtcaccca cggattccat tgcggatttc gatgcggcaa cgggtcaccg gttcacgtca
    15301 tcttctgacg actcttccac tcttgtgcgt ggccctgttc gtcacctctc tgcctgaatc
    15361 ttcagccgcc tcaagtgcct ctccggaatc ggcacgtcgc agttacgagc gcggcgtggt
    15421 tctgtttcgt gaaggcaatg ccgacggcgc catcgaagcc ctgaagaaag cgctcgcgca
    15481 aaatcccaaa ctggcggagg cgtaccacgt cctgggattg atctattttc agagcaaacg
    15541 caatcccgat gaagcgattc aagcctacaa acaatcgctg aaattgagcg caccgtcggc
    15601 tgagattctc aacgatctcg ccgatgtcta tctggcgcaa gggcgaggga ctgacgcgga
    15661 gcaggtgctg cggcaggtgt tggatatcgc gcccggcaat gaagaagcgc acctggattt
    15721 agcgcggctc tacgaggaac ggcatgatcg cacgaatgcc gtgaaaatgt accaatcgct
    15781 ccttcgcatc cgaccggatc acgcggaggc gctctatcac ctggcgagtc tctatgacag
    15841 tcaaggcgat ctcaagcaag cccgcgaata cttgtcccgc ctcacgcagg ccaatcccgg
    15901 acatgccaac gcctggtatc tcctggggcg tctggccgaa cggagcaatg acctgaatgc
    15961 tgccgccgcc gcgttcaagg aagccattgc ggtcaaggcc gatctggtgg atgcccatta
    16021 caatcttgga ttcgtctatc ggagccaggg attgctggtc gaagccgagc gagagttttt
    16081 ggaggtgatc cggtatcgcc ccgagtatgc cgaagcccac ttgaacctgg ggatggtcta
    16141 taccagcttg aaccggctgg atgaggctga gcgggagcat gaacgggccg tggcgctcaa
    16201 gcccacctcg gcggaagccc actacaatct cggggtgttt tacgaactcc acaggaaaga
    16261 catggggcgt gccctggcgc agtaccgccg gtatcgtgac cttggcggac gtgatgagcg
    16321 cgttgagcgg atcattggtg tcggcgggcc ctagtcgtca accccgcaca gggtgaaaag
    16381 ttgcgttgac gctccctcgg cgagtttgct agcatgcgcg ccaggttgtg gttctttact
    16441 atgcgaagtt cccgctttca tagcctcgtc tgggttgtcg tctttgccgt cgtagccctc
    16501 ctggcggtca cgaccggcag cgcggtcgcc catgagctgc accacgccgc gcaccacgat
    16561 gccggaacgc acgggtcagg catctgtgcc tggatgtgcg ccacggccgg tgtacatgtg
    16621 gtcacgccgg ttcatgcgac gcatgtcttg gcgctctccg gcgatgcctc gttcctttcc
    16681 gatatcgtcc atctccctca ggtctctgcc ctctgtcagt cgcgcgctcc acccctgtcg
    16741 ttctaattcc acgtctccct tgtgcatagt ctcgctccgc gactggtcgt cggggagccc
    16801 ggatcaaaca gttgagcgag gtctctcgca tgctgtggat gcattcctcc tttcgatggt
    16861 cgcttcgcga tggtgtctgt tccgtcgctt cgcctggagg ctggatcccg tgaatcgtta
    16921 ggaatggtgt ggcgtcaatt cctctgcgaa gacgtgaagg agtgatgaag atgcaggtga
    16981 atcagtggtt gttccgtctg ggcgtatgcg gtcttacagg gctggtgttg tcggtgtcga
    17041 ctcccatggt ctccgctgcc gacacgaagg ccgaaaaggc attcaccatt gcggtgaccg
    17101 atgctcaggg tgtcgagact gagctgaaga acggcatttt ctattgggaa gaaaaaatga
    17161 gtgagacgtc gttcgtcccg catgagctgc ggcacctgcc atccaagcgc ggcacggcga
    17221 cggtcaatat caagttcgat cagatcaaac agatcgagtt gaagccgggt gccgacaaga
    17281 ctgcaccggc tatgaccgtg accttggcca acgggaagag cggggaattt gttcccgcgg
    17341 tgagcggcag tttcaagggc gagtccgatt tcggccaggt tgaagtcccg atcggttcgc
    17401 tctctaaagt ggtcttcaag taacgtcgga acgtatcgtg tcgaaagggg tcgttcccat
    17461 ggacaatgtc atcgtcgcgc actcggggca ctcaaaccaa tcggtcgcag gatggggggc
    17521 gtcgctggtc tttcacgcct gccttgcgct ggtcgcgttg ggtctcctgc cgaagatgac
    17581 cgtcatggtg gagaaagagc cgttcaagtg ggacgtggcc cttgtcgagc cgccgcgtga
    17641 agtggcgcgc ctggaaggcc caactcctgc gccccgggtc cagccgccca ccccgacccc
    17701 ggtgaagccg cgatcccagc cggttcgtgc ggtcgagcca ccacctcagc cggtgcaacg
    17761 gcaggtggaa accagagtgc tcccgcaagc cgtgcagcgt gaagtccagc ccgtggttga
    17821 aacggtgcgt ccgcaggaac agatccagtc gaagcaggaa gtcgtgcaga tgcaagcgaa
    17881 gccggttgag ccgcaggaag tccacaagac cgaaccggtg gtgcaagcgg tggctccggc
    17941 cgaaatgcag cgtgaagtgg cggcggtagt ggagcagcag gtcatggagg cggcgcctgc
    18001 cacggcccag acctatcagg cgcagcaggt tgtcagcgca ccagcggtgg tcgaaacggt
    18061 ccctgagccg gtgatgacgg ccagcgcacc ggtggtgcac acccctcccg cagtcgaagc
    18121 ggtgccggcg accgcggccc cggtcgatcc cgcccctgcc gcggaatcgg ttgcagcagc
    18181 tgtcagtgaa ccggtcgccg agcctcctgc tcccgttgag gcggtcgtgg tgccgactgc
    18241 gccggtggca gcggtgactg agccggaccc ctcgacgttg cgtgaacatc aagtggtggc
    18301 ccaggcagcc gttgcgcgac ctgctcccaa ggccgattac ggctggctcg ccgactcttt
    18361 gaaacggcgc gtcatcgaac tgcgacatta tcccagcact gcgcgcttaa acggctggga
    18421 ggggaaggtc gtgttgaagg tgtctatcag caatgacggg cagctgaaaa gtgtcgaagt
    18481 ggtcaagagt tcaggacatg aatcgctgga ccaagcggcc atggaagcgg tgcgacgggc
    18541 ctgcccattg cacatgaagc atgagctcac cgcgccgatg gtcgtgctga atctgcccct
    18601 cgtatacagt ttgaaccggt aaggtgattg gggagaaggc aacatgaaca ctcaatcagg
    18661 agcctgtcgg agatcggcaa tcatgataca gagccttacg cggaatgtaa tagtgacggc
    18721 cctgctcgtc tcgacgttag tcggctcggc actggcgatg gggtcgaggc ctccagcggc
    18781 ggggatgccg gccagcgggt tttcgctgac ggatttacag ggcaaggcgc acaccctgga
    18841 gcagtataga ggaaagatcg tcttggtgaa tttttgggcc acctggtgca agccctgcac
    18901 gtccgaaatg ccggcgatgc agacggtcta tgaccagctt cgtgataagg atttcgtggt
    18961 gctggcggtc aatgaattag aggatgaagc caaggtgcgt gaacacattc agcagtacaa
    19021 acatacgttt cccgtgttgc tcgatcgtga aaaccgggtg gccaatcagt acggggtgtt
    19081 tggtctgcct gtgagcgtgt ttatcgacca gcagggcgtg gtgcaggaat acatcaaggg
    19141 cgggttgttg accgagcaaa agatccagga gatcgtcagt cgaattcaac aggctgcgcc
    19201 cattaaggcg gcggcgttgc attgacccaa tgaggactcg cgtacgacat accctgatgc
    19261 cgctcctgct ggtctgcgcc tttctggcgc tgcagggcat tgcgtatccc tccatgctgg
    19321 agcatgtggc gcaacatgcg catcatgagg ccggtgtcca tgggaccgtg atgtgttcct
    19381 ggatgtgtgc agcggggcaa gatctcgagc ccgtgcctga ggtggccccc gtcacgatct
    19441 ctgtcattgc cttgcttgat gagatcgtcg tcgattccgt ctcgatcgaa tcccgcaccc
    19501 tgtggccgtc gcgaggcccg ccgtcttctt ctccggcctg aatcgtttcc ctctgattca
    19561 tcccgtttcg gtatcacccg tagcgtctga gccggggttc catccggcac caggcgcgag
    19621 ctgtatcatc aaccgtgatt ggagaaagga tcgtgtgtca tgtgggctcc cagtagaagg
    19681 tttttggtgt cggtactcgg aatcgtcgcg gtggctgtgg tgagtgtgac gtccatacct
    19741 caggcctatg ccgcctgcgg tgccgtcagt tgcttcgtga caattggatc tcagcagcag
    19801 gtcccgcaat ccggcctgct gaccatgaat tttatctaca gttatacgcc aatgagcctg
    19861 cccagcggat cgacgggcct gattgccgaa gcggaccaga tcgggcggcg catcattccc
    19921 aaccatcata atgaacgctc aacctatacg aactccttcg cgctggattt taattacggc
    19981 gtgaccgatc gcctgggatt gcaggtcacg ttgccctatc tgacccgccg gcatgagcac
    20041 taccatttcc atcagggaca aaatgaagat ctgagccgct tttcggacaa ggggcttggc
    20101 gatattcgag tgatggcgaa atacaatgtt ctcgcttcat tgaaaaatat ggtggtcttc
    20161 ggggttggta cggagctgcc gaccggcgat taccggcaga ccgacaatct gggcggagtc
    20221 ttggaaccgg caggacaatt ggggcgcgga caattcgggc tcgtgggcac gatgtaccaa
    20281 tcgtatgaga tcctaccgca tcggttgaat caattcgtgt tcgccagcta tcgacatact
    20341 ttcaagaaca acgatgggta tcagttcggc gacgaataca ttgtcaatgg cgggttcaat
    20401 ttggtgacgt tgccatggct ggtattcacg gcccaggtga actaccgcta tatgacgcac
    20461 gacagtctga gcgcgagcat cggttccggg ccgatcctgg accgcgggat ccccaacacc
    20521 ggctcttcct ggttcggtgc tgcgccgggc gtgctgttca atatcgggga cacatggcag
    20581 gcctattttt atgcccaggt gcctctctat cgggatgcca acaacaacct tgcgcaggcc
    20641 accagttaca catttggcgt gaccaagtat tttcaattgt tcacgcctgg agcgtgagga
    20701 gtttgacgca gtgtacggtc tagcttcagt agccgacggg ggtaaaacaa tgctccaaag
    20761 tatgcgcggt ctacggacga gtctcatgcc gagacgagca aaacaagcct tgtgtgccgg
    20821 gctgttattc ggattgctac ccacgatgcc cacggcattg gcggagtctc cagcgggtat
    20881 gcagtttggt cccaaggtca ccaccgaaca taaggtgaaa agcttcgtgg gcccgtcggt
    20941 gcagatcgac gaggcggggg ccttgtcgct ggcctggatg gaagaaaaca aagaggtgcg
    21001 gtcggtcatg tatgcccgga gtctcgagcc tggaggaccg atgggtgccc cagtgcgcat
    21061 caaccgcgtg gaggacatcc cgtactggag acaggaagcg ccggcgctcg tggtgcaggg
    21121 ggaagacgtg ttcgtgacct ggggcctggc ccatcccaag gctacgcccg agcaaccgtt
    21181 cgcgaccgaa ttgcgactga gccattcgaa ggacggcggc cggactttcc agccgtcgat
    21241 cgtagtgaat gacgatccgg gtgtcatcca acataccttc gatgcgctcc atcgcgattc
    21301 ggagggacgg ttgcatgtgt cctggatcga tggacgtgaa ggcaaaaaag atcccggcac
    21361 ctatgtcgcg cggtcgctgg atcaggggca gacgatcacg aaaaatgcca aggtggacga
    21421 ggggacctgt gtctgttgcc gaaccgccat cacgagcgga cctgacggaa cggtgtatgt
    21481 ggcctggcgg aaaatttttg aggggaacgt gcgagaaacc gtcgtggcgc gttcgacaga
    21541 ccatggtgag acgttcggct catcggtcat cgtcggacat gacaaatggg tctttccagc
    21601 ctgtccgcat cggcccgcct cgatgggcgt cgactggcag ggacgactgt atatcgtctg
    21661 gtatacggaa gggaccgacg aaattccggc ggtctatctc gccttctccg atgatcgagg
    21721 ccagacgttt tcgccgaagc agcagttgaa tgtgtcgaag aacacctttc ccgaccatcc
    21781 gcagatcgcg gtggatcctg aaggcaggct ggttgtgatc tgggaggagc agggaccggt
    21841 caaacgagat gtggtcatga gtgcctccac cgatcgcggg gcaacgttca ctgcgccgca
    21901 gaagctgaac gagcgaaaaa gccagacacc ggtagtcgcg gtgaatcggc acgggttatt
    21961 tgccatggcc tggatggaac atgggatgcc gggccacaaa attgtcatgc agaccctgcg
    22021 gatgccgtcc gtcacggcgg cagcagcggc aggccagtag atgggacggc gcgtgtgatg
    22081 cggttgggat tcgtgcagac ctttgccctg tttgtggcga tcggactctg gtgcgaccct
    22141 gcactagccg acgaccggct agcggcgctg aaggtcggac gggttgcgcc cgggactgtg
    22201 gcggccccgt tcgagctcac atcactcgat ggcgcagctg tcgacctcgc gcagttgaag
    22261 ggaaaggtcg tcgtggtgaa cttctgggcc acctggtgcg ggccctgcaa ggaagagatg
    22321 ccggccttcg agcgattgcg ccggcagctg gatcccgaac gttttgcgct gatgacgatc
    22381 acgaccgacc tccaacgcga gggcattaaa cagtttctgg ccaatcttca tgtgcaggtg
    22441 tccgtgttat tcgatgaaga tcaagcggtg tcccaagcct acctcgttcg ggccttgccg
    22501 acgacggtag ttatcgaccc acagggcatg ttgatcggcc gtgccgtcgg accccgcgac
    22561 tgggatgcgc ctaatgtcgt gcacgcgttg cagagcctga tgccatgatg cgtgtgacga
    22621 aaccttccat tggacttgcg gccgcgctgg ctggactcta cctggttctc gccgtcttct
    22681 cagtcgcctg cgtagtcgat catgccgatc cgaaaccggc cgcccatcac cacggcggta
    22741 cggtctctca ctccagtttc tgtgcctggg cctgtcaggc gaatccgaca tcggatgccg
    22801 gccctgtggc gctctttctg cagccgtttt tcgtggcgac gctcgttgtc gagagcagcc
    22861 atgccatcgt cgcgggaggc gtgggcttcc acaccgcctc gcgcgcgcca ccggttcagt
    22921 cataactcct ttttatagcg ctaggtcgtc tagcttctct tctcgtccgt tcagacaggg
    22981 gcgcgagggg attgtctctt ctgtcgtgtg cacagttgtg ccgggaggat ctgtatgtgg
    23041 gcccgccgtg attcattcag acttcatgcc gctttatgtt gtgccttgtt gtcagtgcca
    23101 gtgaccgttg tgccctcaat agcgcaggaa gagacagcgg ctggcgccgt tgtggagaaa
    23161 agcgcacgcg agcgcgacct gcgtgaccaa ctgcagaaca ttcttcgtga gttggaagag
    23221 ttgcagcagc aaccggccgg cggcgcagcg gccaagccga ttcaaccggc ccagccggcg
    23281 gcagttgagg aatcgtccgc atcggtcgcg gccgagccga taccgcaata cgagctgtcc
    23341 gacgtcagta tcgtgagcga tcgtgtgcag cgaaggcctg agggtttgtc gatgtcgtcg
    23401 accgaacaat cggaaacgga agcccagcca acccgaacga tgaaggaatc gatggagtcc
    23461 ctgcctggcg tggtattgcg gcaggccaac ggtccgcgcg atttcagcat gatgatccga
    23521 gggcaagggg ccaagacgac gttcgccgtc cgtgacatca agatgtacga ggatggattc
    23581 attcaaaccc aatctgacgg cttgtcgcga ttggacattc atgacccctg gttcatgcgg
    23641 agcgtggaag tgacgcgggg tgcctcgtca tcgctgtatg acaactatgc cctgggtggg
    23701 atggtgcact ttagaaccag gcgggggagc gatatcaacg gagtcgagac attcctgagc
    23761 ggcggctcct tcggctacca caaggaaggc attgccgttg gccagcaatt cgaaaatctc
    23821 gatgcgtcgc tgttcgtcag taatgtgggg gaagacggat tcatccggaa cagcagttac
    23881 aacactcaaa cgatcaacct gaacttgcgg ttcaagatcg acgacaagca gaacttctac
    23941 ttcaaggcca tcacgaactg gctcgatgcg cgagtgccga cccgtttgac tcaatctcaa
    24001 ttcaacgccg accatcggca ggccggtggt accaacgtgg tgtgtaatgc caacacctgt
    24061 agcgatgcgg aacggctggc gcagcgccgg ctcgatcgac gtaccatcat cggaggtatc
    24121 tacgagcgtc agatcaacgc caatacggtg ctgacgatcg aggctgatta cgatgtgaag
    24181 gacatcaatc aaaccttctc tcaaatcagc gacaacgtga atccgaacta taagcattac
    24241 gccgacctgc gccacgacgg acgactgttc gacatgccgt tacggagtta cgtcggcttc
    24301 tttctcagca acatggagca ggaagcgcag acgtttcaga acctcgccga cggcttcggc
    24361 actcgcggcg cactcctcca aaattcacgc ggcacgatca gaaacgtcgg tggccgtttc
    24421 cgggaagaac tggaatttat tcccaaggtg acactcgcgg ccggattggg atttgagcag
    24481 tctcagctga gcgtccagtc gatcgggtat acgggcggtg ccgtaagcag ccgtgcgggc
    24541 gctgatcgca gttacaccaa ttgggcgccg gaaatgtcgg ttacgtggaa gccgactgat
    24601 gctcaacggc attgggtgcg cgcatcgacc gggtatggca ttccgggatt tgccaatctc
    24661 cttagagatc cggtgaccgg gcagccggga acgaacttcg acctgaagcc gcagaagaat
    24721 ctcaacttcg aaatcgggac cgagtccaaa ctgacgaaga ccctcaccgt gcaactcgtc
    24781 gggttctgga ccttcttcaa ggacgaaatc atcacacagg cggtgtcggg taccaacacc
    24841 gcctcagtca atgctgactc ctcacagtac aagggcatcg aagcgttcta cgactggcga
    24901 ccgatggagg gtttgcgatt gtccggtgcg tatacccata tcgaggcgaa gtacgtcaac
    24961 tttgccgatc ggttgaacac cgccgccggc ttcctgacgc gcgacggcaa caaagtgccg
    25021 aacgtgccga ccgatgtgct gaatacgaag gtggcttatg accatacggc cactggctgg
    25081 ggcgcctggg tcgaggggag ttattacaac agttacttcc tgaacaacag caatacgttc
    25141 ggcattccgt cctacatgat cgcaaacgtc aatgtgcaca agaacttcga tctcaagaat
    25201 tcctggttcc gattcgcgaa gttctatgtg gaggtagaca acatcgccga caagaaatac
    25261 gcggcttccg ggcaggtgat cggcggagaa accgccgggg ctgccgccgg gcaacaggcg
    25321 ttctttgccg gctacggccg cgcgatttat gggggcgtga cgttcggttt gttctaaccc
    25381 tgtggtcgtg agcggcaacg tcgatggttg ccgctcacat cactacttca aaggagattg
    25441 cgatgaacaa gcaactcttg cgtgtgggag aagcagcgga tgtgttggcg gtgagccggt
    25501 ggacgattta tcgctgggta gaagacggcc ggttggaagg caccaagata ggacgcggca
    25561 gtctgcgggt gtttcgtgcg tcgctggatc ggctggtcca aagcaacaag acgcacgaaa
    25621 tgaatctcag tgtatgacgc gaatagccgt caggtcatcg tcggtcgtca gcgcacgcgc
    25681 gacgagcctc gtgcgcctgc tgctcgcgtt ggtgctaatc gccatggcat cgggttgtgc
    25741 ggggggcgta ggtgatccag ttcccccgtc gctcccgcag tatgccttca tcaacggcca
    25801 gtggttcgac ggggaaggat ttcgggcagc cacctggtat tccgtcgaag gccgcctgac
    25861 gaagcggcct ccagcgggac tggttcagac cgtggatctc gctggtcttt acatggttcc
    25921 gccctttgga gaagcgcaca atcacaacgt cgaagggccg tggaatgtac aggcggtcgc
    25981 gcagcgctat ctgcacgacg gagtgtttta cgtgaagaac cccaacgacg tgcgggactt
    26041 cgcgcagcag atcaagcacg ccatcaacat gccaacgagt atcgatgcga cctttgcgca
    26101 tgtcgggctt acgggacatg gcgggcatcc cgcagcgtta tatgaagatg tgttgcgaat
    26161 cgggcggtat gagccggcgg tcgggccgat cgaacgggga tggtttgaaa accggtcgta
    26221 tgtagtggtc gagacggatg ctgaggtgga ggccaagtgg ccggtgatcc tgcgcggtag
    26281 ccctgatttt ctcaaagtct atctggtgca ttccgaggac gatggggagg aagcgaaggt
    26341 caaacctgct catcacagga aagggctgca tcctgcgtta gtgccgggta ttgtcgcgag
    26401 ggcacatgcg gccgggctgc aagtcacggc ccacgtcgaa acggcggctg atttccgcca
    26461 ggcgattcgt gcgggagttg atgagctggc gcatgtgccg ggttggttga ttcaacgtgc
    26521 ggacgatgcg gaacgtgccc ggttgacgga ggaggatgcg cgcctggcag cggatcacaa
    26581 agtgcgagtg gtcactacca gtgtggcggg acaggcgatg ccctccatcg gtggacatca
    26641 ccagcatggt tctcatgcag ggcatgggac cgggcagccg atgaagcaca atgcgttgcc
    26701 cgctgatgcc gcttctcatg tgctgaagga caatcttcac ttgctgcagc gggaaggggt
    26761 cacactcgtg atcggcagcg accatgcgga gacgtcgctg gccgaggtgc tgcacctgag
    26821 caccttgcat ctgttcgaca atcgcacgct cctcaagatg tggtgcgagg cgacaccggc
    26881 ggcgattttt cctgcgcgtc gaatcggaaa gtttgcggag gggtatgagg ccagttttct
    26941 cgctttggca ggcaatccca tcgaagattt cgatcaggtg caggccattc gtcgaaggtt
    27001 caaacagggg gtgccgttgg acggtgccct tatgaaggac gctgcctggt cggcagcggg
    27061 tcaacggagt cagtagtgcg tggtgcgctc aaccagcatc gcgtcattgt tcattagtca
    27121 ttcacggtct gggcagatcg gaagcgaggg aatgaagtgc agtgatcgtg tcggcatcat
    27181 agtcattgga ctcttggcag tggctctatc gggcggtatc caaccgcctg cggggctcgc
    27241 agctgaagag tcgcaagagc aggaggcgcc ggtgatcgcg gtcgaaccgg tggaagtgag
    27301 tgggaaacgc atcgagaacg tcgaggatgt gaaacgggag tttgcgcgcc gtcccggcag
    27361 caacatcctc atccaggaga aggagattac cgaatcgcgc gcgttaaatt tgcaggacgt
    27421 gctgcagttc gcgccgggcg tccggtttca atcccggttt ggtgccgatg aagggcagtt
    27481 tcaaattcgc ggcacctcct tacggaataa tttccaccat cgcggcatca atattctgat
    27541 caacggcatt ttcttcggcg acgccgacgg attttccgac tttgaatcga tcgacctgct
    27601 ggcgtacgaa cgcatcgaag tctacaaggg ggcgaatgcg ttgcggtatg gagccaacag
    27661 catcggtggt gcgatcaact tcgtgccgcg cacgggctac agcgcctcga cgctgcaaat
    27721 gcggatgctc ggcggcagtt tcggcatggt gagcgggcag gtgtccagcg gcaaagtgtt
    27781 gcagccgttc aaggtgggca acatgagcgc cacgatggac tactacatca gcgtgtccgg
    27841 caatcgccag gatggctttc aggataacag tcagcaggcc cgcgaacgca tcaatgccaa
    27901 catcggcttg cagctcggca accaccagga aatccgcgcc tactttctcc aggccaatgt
    27961 ggccgagcgg attcccggtt cactgacgaa tcagcagttg tttttcaaca ggcaacagac
    28021 cggagggcag agtcctcccg gggcgccgcc gttttttgcc tgcgtgtcga gcaaccaggc
    28081 ttgtaactgg ggccgatact acaccctgca acggatcggc attgcgtacc ataacgagtt
    28141 cgcgccgaat cagtttttcg aaatcatccc ctatttctcg aaccaattcg tcgaccatcc
    28201 gatcttccag acgatccggc aggaaaacaa caacgtcggg ggagaattcc ggtatgtgaa
    28261 ctccaattcg ctgttcggga aaaataactc cttcgtcgcc ggattccagc cacggtatgg
    28321 tcatcagcgg cagcagcggt tcgtcaatat caatggcaac atcggagcca tgacgcagaa
    28381 ctataccgcg aagaccacct acttcggcgc gtatgccgaa gatgcgttcg acgcgacgaa
    28441 ggacttcacg atcgtgatcg gcggtcgatg ggactatacg gggcgtgagg cgacggtcga
    28501 taacttcggg ccggcgggca atcccttcaa cccggcgacg ccgtctgtgc cgacgagcac
    28561 gcagaagccc ttgcaacatt tcggggcgat cagtccgaag ctcggattcg tctatcgcac
    28621 gacgccgacc tcgcagctct atttcaatgc cagccggtcg tatgaagcgc cgctcaacgt
    28681 agagttgctc tcagccctca atgccaacgg ttccgcgaat accggtttcc tgaatctgga
    28741 tgcacagcgg gcctggcaat tggaactcgg ctatcgcgga acatcggcgg accggcggta
    28801 tagctgggat gtgacggtgt acaacctcga gatgcagaag gaaattctcg cgtcgaacat
    28861 caacaacacc ggcacctttc aaaatgcgaa tgggaccagg cacacgggcg tggaagcggg
    28921 cggcgccatg gtcctgaaga aaggcctctt cgcgcaaggc ggagccggca aggaagacag
    28981 tctgcaaacc cgcctggcct acacctggtc acgcttcaag ttcacggacg atgtgcgggg
    29041 tggaggaatc ggcggcccca atgtattgat tgccaaggac ggcaacacgg tggccggcgc
    29101 gccggagcat agcctgaatg tggaagcgcg gtacgatcac ccgtccggtt ggtggatcgc
    29161 gccaaacgtc gaatggtcgt tgtccggttt ctatacggat tacaacaaca cgatcaagaa
    29221 tccttcctat gcgctgatca acatgcgatc aggatggaat atcgatgagc attggacgtt
    29281 gttcgccgag ggccggaacc tcacgaacaa gacctatgcc ggtgcggttg tcgtcaacga
    29341 ctcactgaat cggttcgcca acccgggatt cgggatcagt gccttcggag gagtcgagta
    29401 taaattttaa gtcgcggtga agttggcgat gcgggctcat cgtcaggtga gcgtccgcat
    29461 cgtggctgcg gggatggctt cagtgtggcg tcaggaagct ttgggggcgt ccctttgcgt
    29521 aaaaaatggg atggacggcc gtctcccgaa catgtgataa caggattcgt cgggtatgac
    29581 cccggatagg catgtcctgg taactgtagg gatagaccgt gccggccatc tacggacttg
    29641 tcactgttct gctacttgtc tggagcatgg taccggtcta cgccgagccc ggctccacgt
    29701 cgccacccac cgcgaccttc gcttcgcttc cccgaattga atcgattcaa ctgtcccctt
    29761 ccggccggca tctggccgtt ctccgccatc atgatggaca gacgtttctg gaaacccaca
    29821 ccgtcacggg acaggatgcg cacccggtcg tttctacgga caatcgcgaa tacatcatca
    29881 cctggtttcg ttggatcaat gacgagcgtc tgctggtgag catgcggttc gccgctaccc
    29941 cggaggcgac agacacggtt gagactcgat tgatggcgg
//
LOCUS       DAOQPD010000047        29780 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_696_length_29780_cov_27.495879, whole genome shotgun sequence.
ACCESSION   DAOQPD010000047 DAOQPD010000000
VERSION     DAOQPD010000047.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 29780)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 29780)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29780
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_696_length_29780_cov_27.495879"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..366
                     /locus_tag="PK063_11740"
     CDS             <1..366
                     /locus_tag="PK063_11740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97770.1"
                     /translation="VSGHIIGLLKEYMRDLVEQARQESQAQHTFGFSAPPYQPDHAIA
                     DLLSILDDRIESEGLQVGMPLEFLHEMWRHCNEARSQVMEQVWLESNLGPPGSSKDRI
                     RELTYAALITHLESDAQQE"
     gene            complement(399..1217)
                     /locus_tag="PK063_11745"
     CDS             complement(399..1217)
                     /locus_tag="PK063_11745"
                     /inference="COORDINATES: protein motif:HMM:NF014724.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HMZ97771.1"
                     /translation="MDLTPMWFGVYKASKYLLYPLSWIVLSGLLTLLIASLPVTPRRT
                     TWVRRLAFSTVLLLFLTATPLLSHLYISQLEARYPPFAVPPVAKFDAVVVLAGGVFHK
                     GSLRPADETSDPSRQRTACGAELWFQGLAPKMVLAGGDATVLRTGPPESREMKRWAIR
                     LGVPESVIHVEENSRTTYENAVQTRALLGPAHILLVTAAYHLPRAVGLFKKQGFTVTP
                     VACGYESTHHPQQAWEEKTVFDFIPTARALLLSTQTIDEVAGILVYWITGKWQP"
     gene            1309..1791
                     /locus_tag="PK063_11750"
     CDS             1309..1791
                     /locus_tag="PK063_11750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EVE domain-containing protein"
                     /protein_id="HMZ97772.1"
                     /translation="MAEGRHYWLMKSEPNVFSLDDLARAPKQITSWDGVRNYQARNFM
                     RAMKVGDQVLFYHSNAQPPCVMGIAEVVKTAYPDATQFDPHDVHYDPASPADQPRWDV
                     VDIRFVRKFAAPLSLDLLREQVRLKGMELLRKGSRLSVQPVKPSEWDEILRLARTHRD
                     "
     gene            complement(1848..2093)
                     /locus_tag="PK063_11755"
     CDS             complement(1848..2093)
                     /locus_tag="PK063_11755"
                     /inference="COORDINATES: protein motif:HMM:NF017885.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HMZ97773.1"
                     /translation="MRIPNKVVLPFGYHIMIRQVTDSEMDRQDANADGIWDNEAKTIY
                     IRKRLPVTRRRYILAHELGHAWLDWQHRYLDDGKARS"
     gene            2289..3074
                     /gene="ricT"
                     /locus_tag="PK063_11760"
     CDS             2289..3074
                     /gene="ricT"
                     /locus_tag="PK063_11760"
                     /inference="COORDINATES: protein motif:HMM:NF041131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory iron-sulfur-containing complex
                     subunit RicT"
                     /protein_id="HMZ97774.1"
                     /translation="MNDRMVYHPAMVDKLLAQELAKPYPSVIRIVGVKIRDRGEVKKF
                     DAGEATLAVGDRVLVEVGGELSYGVVYGAPQATPFIPPMRVIQSIARKATAEDAATID
                     RYERLASEGMRACREQAVALGLKMKLVEVFCSFHRRQMTFVYTAEDRIDFRELVRLLA
                     RRFGGRIEMRQVGVRDEASRLGGIDTCGLVLCCAAFLTEVKPVTVKQARVMGLPVDDP
                     KLLGVCGRLKCCLLFEAMESQPSSSSSKSSALINPARTRLASS"
     gene            3194..4285
                     /locus_tag="PK063_11765"
     CDS             3194..4285
                     /locus_tag="PK063_11765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase C-terminal
                     domain-containing protein"
                     /protein_id="HMZ97775.1"
                     /translation="MPQVLVLGSGKIGSLIAGLLSAKGQYQVHLADLTLDAPKRLIDD
                     LALTTVTPCALDVRRPDSVVAYVTAHRFDAVISCLPYFYNPAVAEIARAHHLHYFDLT
                     EDVAVTGCVKRISEGADHAFLPQCGLAPGFISIVTNDLIGHFESIDHVKMRVGALPVH
                     PSNALKYSLTWSTDGLLNEYGNVCVGIERGEEVHLRPLEGYETIELDGLLYEAFNTSG
                     GLGTLADTYRGRVRTMNYKTLRYPGHCEKIQFLMNDLKLNEDRETLKRILERAIPQTH
                     QDVVLMYAAVTGTRQGELFEETYVKKVYPRMMLGRTWSAIQVTTASSLCCVLDLVLAQ
                     PSAYRGFIRQEHFPLRDVVNNRFGDCFRS"
     gene            4293..5849
                     /locus_tag="PK063_11770"
     CDS             4293..5849
                     /locus_tag="PK063_11770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HMZ97776.1"
                     /translation="MTTEELFTRLGLAREQSGGGGSSSTWTRTTPAGVVESRNPSTGQ
                     TLGRVYGCTDDEYDALVIGLQHMQKVWRTVPAPKRGEVIRRIAEALREQKDALGSLIA
                     LEVGKIKAEGDGEVQEMIDMADFAVGLSRMLYGYTMHSERPQHRMYEQWHPLGVIGVI
                     TAFNFPVAVWAWNAFIAAVTGNTVLWKPSPKAPLCAVAIQQLCNRVLEDAGYPGVFAL
                     CTTDRVELAERLVRDERLPLISFTGSVPVGRQVAEVVGRRLGRSLLELSGNNAIIVDE
                     TADLELATRAIVFGAVGTAGQRCTSTRRVIVQDSQYDKLVSRLVSAYGQVTIGDPLQP
                     NVMMGPLIDREAVARYQSALEDVRQAGGEVLCGGRVLSRPGYYVEPTIVRAQNHWKIV
                     QQETFAPILYVMTYRTLDEAIDMQNAVPQGLSSALFTTHLHHSEAFLSASGSDCGIAN
                     INIGTSGAEIGGAFGGEKHTGGGREAGSDAWKAYMRRQTTTINWGTELQLAQGITFGR
                     SEGGNHGASR"
     gene            5833..6426
                     /locus_tag="PK063_11775"
     CDS             5833..6426
                     /locus_tag="PK063_11775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97777.1"
                     /translation="MGQAAELDAVIARMTADFLAQNTAAGMLRRALDDVGVGFVPVMD
                     HLTIRTMNIDQRAEEFVALGYGYDETIYYDDWYAKVFRKAGYPALFVDQAYPDARGHT
                     SIIPRWVDKFGDRVFHHVAVRVEDIEQAILKLKSKGVVFAGEIVGARGGPLRQIFTAP
                     EMIDGQPFSVLELAERHQGYQGFLPPQADSLMRSTVR"
     gene            6579..7649
                     /locus_tag="PK063_11780"
     CDS             6579..7649
                     /locus_tag="PK063_11780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c peroxidase"
                     /protein_id="HMZ97778.1"
                     /translation="MVRTVLPLCFILVLLCVATFGIGESLVGASPSGHAPHGTVTIDG
                     ITVPDIGPLPTAVPIPSSNVNYAAKIELGKQLYFDGRLSKNNAISCAFCHNPGTGFAD
                     SRQTSIGVGGGIGGRQSPTVYNTGFNHVQFWDGRARSLEEQAIGPIHNPVEMAETHEH
                     VVAKLGKIKGYQQEFRAVFGTEVNLQGIAEAIAAYERTVLSTNSAFDKYVLGDVKAMD
                     EAAARGLGLFKGKARCILCHNGPNFTDNQFHNLGVPQVGPMKEDLGRYNVTRADKDKG
                     AFKTPTLRSVTETAPYMHDGAFKTLEEVVDFLDQGGGSNPRLSPLMRPLGLTTEEKAD
                     LVMFLKALTGEPIKFSMPQLPK"
     gene            7760..8266
                     /locus_tag="PK063_11785"
     CDS             7760..8266
                     /locus_tag="PK063_11785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1264 domain-containing protein"
                     /protein_id="HMZ97779.1"
                     /translation="MFRQLCVLGASTLALAMGGPALAADMKPGPADGFDIHVMAPHKM
                     EDGSVAGPFHHYCKAIKPEVLQCLLFESTAPNAVLTDVEYFVAKPVSRSAVPLDVWNK
                     FYHDHEVEIATGRVQVLDMPDAQAKEVAAAAAKTDGIIFHLWPKGAKAPDGSVGHPTS
                     VGHKPRTE"
     gene            8320..8874
                     /locus_tag="PK063_11790"
     CDS             8320..8874
                     /locus_tag="PK063_11790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1264 domain-containing protein"
                     /protein_id="HMZ97780.1"
                     /translation="MRSAIAMIGLCAAALTATGCAETSHDMKSTAAAAPAATAAKAMP
                     TPAQGYTIHVMAPHKFEDGTVHGPYHHYCKPISPEILQCLLFESTDSNALLTDIEYFV
                     AKSVSRAHVPLETWNKYYHDHEVEIATGRVQILDMPDAQAKEVAAVAAKTDGIIFHLW
                     PDGAKAPNGEVGHPQSVGHKHRTE"
     gene            8959..9405
                     /locus_tag="PK063_11795"
     CDS             8959..9405
                     /locus_tag="PK063_11795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="c-type cytochrome"
                     /protein_id="HMZ97781.1"
                     /translation="MKSVSLFLYAWTVVGVGAIAWSADSEVLRPRVPVDQIESARAVT
                     NPFPVTPEMREKGKALFEGKAFCRACHGADGKGLGLDLDYSTFKGPLPRNFTDKMWQQ
                     ARTDGELFWILKNGSPGTDMASFIPLVLTEEEAWQVLMYVRSFGGR"
     gene            complement(12134..13252)
                     /locus_tag="PK063_11800"
     CDS             complement(12134..13252)
                     /locus_tag="PK063_11800"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97782.1"
                     /translation="MPSADAPSLVIEQGTCYALFAYDIGLAINLDEAERHVTAIKERG
                     RMRHKARAPHYFEYRPAPLRLIQETASLDFGDYRSSEAVEVMLYDFGAVTVIYRIPIN
                     GPFEGLLSLSESLYENERLLADSRHRLDQLVRDIRLAIDRPSVSPEVEDYLVFSVEHC
                     SPSAIQALGTPFEPMFAHVLRSERTRLSDQEIREATSCRISFSRDDTALIDWNAAIVF
                     GEDMDDVRAVLEFVNVELLEMRTLDEQLDQALDQGYVALTRKARVTSWLPGSHEAALT
                     QIGQLQVDSAVLFERVANTLKLLGDQYLARVYRLASQRFHLEAWDASIIRKLQTLDSI
                     YGKMSDRATTQRMEVLEWIIIALITISIAVSFLPMTSH"
     gene            13463..14140
                     /locus_tag="PK063_11805"
     CDS             13463..14140
                     /locus_tag="PK063_11805"
                     /inference="COORDINATES: protein motif:HMM:NF024811.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HMZ97783.1"
                     /translation="MPTIKAIIFDFDGVLFDTEAIHFAVFREVLRSEGIPLTLSRYHA
                     AYVGLSDEACFRAILNDHRIVVPKEDIQQLVRRKTDLVQRAFRASLPRVSGVSEFVSD
                     ASMRYRLAIASGALLQEIVLCLKLGSMLTMFEHITAAGDVREGKPNPAPYLHALHALH
                     GRSPIAANECLVIEDTPHGVEAAHKAGMRCVAVTTTLPADRLAQADLVVPSLHALRLE
                     DLTVQLP"
     gene            14278..16680
                     /locus_tag="PK063_11810"
     CDS             14278..16680
                     /locus_tag="PK063_11810"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97784.1"
                     /translation="MSRTTALSANSSPYAVESRHVIEREAVEFLANSVTLPFSSSDIT
                     AGSESELQAAVLGRSADVDLAQTIHRSNYLKNIRDRTETGESPRIVIQQLQEFLNDSQ
                     STVWENSWVRFPRNMLNKEANQLLACDLRANRRDPKGTPRTDIDRFLVTEQGEEWVRV
                     PVSYVLRLALAQVIGAIESDVPMLAKEGRRLLDHFLNDNSSPETFSFYVSGMDPARGM
                     GKAIAHETAIRFLLTQLLVQYANRAFGLDETGQHAIVYASPHPPVRQRRLNGLISDSF
                     YRELFVNPCLSGWDQGEDKSRYMGLCHEVLSRSQLNAVVRLKDAGIITRNLVVLPATS
                     NISLANNGTHLSLGSRMLTETLQANGKRFTAVHEKVLGDLVIKIVEHFLPLFVGTYSA
                     APYRMNFRDFHPETALGFLPHELDFAHLRMLWRRWKKKAGLSVFGRSITPLGPPWLDR
                     AISFIFNLRGDCLPDFRLIDYLVCLLSTEQSPALDGIPGNDLRLKRDLGQLGVFDERM
                     SLYLLYKLRAQSVMGFSGFEGRHYSLFWNHTDDFAQAASMQALVTALAFQYIARGEVS
                     HEDIPDDPMTESERRQYLFATAVGVGTVNVREAGPNRFLTRILMKTHKTRASRRYAGH
                     LRVRCEDYRMALVAMLEEDASDLIESFQMQECMRSLRDRLSNQDSSTAGKLTHGILNS
                     VGSPSAFDLSGEEFALAAEGYYRRELRAQYLREACESVREELCAIDQGVSEQATQYRG
                     LVTAMIGTRSAVDAFTEEQPRLLAETADAKTLQRCLGLCIMSIAHARISAGRTEEQPL
                     AS"
     gene            16677..17702
                     /locus_tag="PK063_11815"
     CDS             16677..17702
                     /locus_tag="PK063_11815"
                     /inference="COORDINATES: protein motif:HMM:NF014696.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylserine decarboxylase"
                     /protein_id="HMZ97785.1"
                     /translation="MSMPHQYIERDSNLVVTERFCGDQWLNWAYRALWENANWFMKAL
                     TSRRTTQALGFFNYDRPFTSTQAAVARFARALSVDLSECLDSSDRLNTPRRLFQRRLR
                     YWQVRPMDDDPRAIVSPADARLLIGSFADDSSIFLKGKFFDYDELLGKHRPQWRRLFQ
                     RGDWAIFRLTPDKYHYNHCPVSGRVVDCYEINGRYHSCNPGAVVVAATPYSKNRRIVT
                     IIDTDVPGGTRVGQVAMIEVVALMIGQIDQCYSSVAYDDPQTMQIGMMLKKGCPKSLY
                     RPGSSTDVLLFEPGRLSFSEDLLRNRFRPGVQSRFSEGFGRPLIETDVKVRSTIAWRL
                     ERGIDGR"
     gene            17692..18747
                     /locus_tag="PK063_11820"
     CDS             17692..18747
                     /locus_tag="PK063_11820"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97786.1"
                     /translation="MGDSTSVIALLIVLYGLLFWWAFRTLPQESWQFVASMPRMKLSD
                     GRWVGTNLTYYGAWTATAVVFAVAMAIVLMQSVAVALDAIALLAVVLLGLCVPASKIL
                     ARLIEGKANTFTVGGASMLGLFLAPMIIDGINLVLNWTGKGALPAAAVLAALSVAYAF
                     GEGTGRLACLSFGCCYGVPLQESGPRLSAWFQQYHIAFVGRTKKAAYEGDLEAVPLIP
                     IQALTAVMSVGAGITGVWLFLQGHMAASFLSTIAITQLWRVASEYLRADFRGVGTLSW
                     YQILSLLGVLYAFVLTFWLDTFSPSVPNMRLGLRDIWSPGIILALEALWLGIFFFTGR
                     SRVTASTLTMRVLRDRI"
     gene            18951..19475
                     /locus_tag="PK063_11825"
     CDS             18951..19475
                     /locus_tag="PK063_11825"
                     /inference="COORDINATES: protein motif:HMM:NF025910.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ97787.1"
                     /translation="MNIADDLFNDEERKQLAYEAASAMAKRALTIDERSAHAHFLYAA
                     SLGSGERLKGLSKGGLVLGELKQHIRRAIELNPTHAQALQMMGGLCAELPWLLGGSDK
                     DAELYLKRAIAADGRFTNAHLILARLLMRQGRLAEAREHIESVLHAEHPHYPYAWKHT
                     FRPEAERLLNLLSK"
     gene            19880..21340
                     /locus_tag="PK063_11830"
     CDS             19880..21340
                     /locus_tag="PK063_11830"
                     /inference="COORDINATES: protein motif:HMM:NF013543.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter"
                     /protein_id="HMZ97788.1"
                     /translation="MAVKQSSAWPFILLGVALVIALGFEFVNGFHDTANAVATVIYTH
                     SLPPHAAVIWSGLWNFIGVMMASGAVAFGIVSLLPVELILQVSAGAGFAMVFALLIAA
                     IIWNLGTWYIGLPSSSSHTLIGSVIGVGLMNQLMAGSAEATSGVDWAQALNIGKSLLV
                     SLLFGFSVAAFLLLVAMRAIPIASLYRAPQGKTPPPLWIRGILILTCTGVSFAHGSND
                     GQKGMGLIMLILIGTVPTVYALNRTVDISYTPAFVETSRQAERTLDRYTHGQPAPTDP
                     RHEVGQYLRSRQLMPETIPALRALSAEVREGISAFGSVAQVPDEQTGNLRNDMHLITE
                     ALRRMEKQHDPPLSAPDLKILKEYRSTLDTATKFIPTWVKAAVALALGLGTMIGWRRI
                     VVTVGEKIGKAHLTYGQGACAEMVAMGTIGAADMLGLPVSTTQVLSSGVAGTMAANQS
                     GLQWNTVRNLLMAWVLTLPASIVLSGSLFWIFRHLV"
     gene            21370..22335
                     /gene="corA"
                     /locus_tag="PK063_11835"
     CDS             21370..22335
                     /gene="corA"
                     /locus_tag="PK063_11835"
                     /inference="COORDINATES: protein motif:HMM:TIGR00383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015087 - cobalt ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="HMZ97789.1"
                     /translation="MLSAFVLEEGRVIQAQIDDKDDLTRKDLVWVDLAYPSEEERELV
                     QSVFPLELPDDEELQDLEASARYYQDQHGIHIRSTFVQTADDVASIVNMSFSLHQGRL
                     LTVHDDDLSLLRLFRMQARSSRGMVRDAADILLSCYELGVERDADVLERIYTALDEVG
                     TVVLSRKKEITSRIMRDNVERIAAQEDLNSKVRLDLIDNRRALSFLLRSRVLSPDQAQ
                     RVKGVLRDIDSLNGHTGFIFDKINFLMDALLGMINLEQNKIIKIFSIAAVVFLPPTLV
                     ASIYGMNFEHMPEMKWPLGYPMALLLMVFAGGAPYLYFRQKGWLD"
     gene            22376..22696
                     /locus_tag="PK063_11840"
     CDS             22376..22696
                     /locus_tag="PK063_11840"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97790.1"
                     /translation="MNSQQNNKPSRPGRKGALAKLSEPQVGDAPPKLKSKPSKRPMLH
                     DASTVPPQKHVLTQEEFRARVSRKAFELYEIRRSVTEVDDWIAAERLVKVELLSEERG
                     AGSV"
     gene            23236..23556
                     /locus_tag="PK063_11845"
     CDS             23236..23556
                     /locus_tag="PK063_11845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HMZ97791.1"
                     /translation="MRTKTKQLTDVATVFHALSDETRLLILEQLKGGEQCVCDLTEIF
                     KTGQSRLSFHLRVLKEAGLILARPEGRWVYYSLNSDAVEELQDVVNSLKAVSSRAARQ
                     GCCP"
     gene            23600..24709
                     /gene="arsB"
                     /locus_tag="PK063_11850"
     CDS             23600..24709
                     /gene="arsB"
                     /locus_tag="PK063_11850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008490 - arsenite secondary active
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACR3 family arsenite efflux transporter"
                     /protein_id="HMZ97792.1"
                     /translation="MKLMDAAGVIAQQTLPTEKRLNVFERYLTVWVAFCMVAGMLLGT
                     SAPGLIQMLRGMEFGQDSHVNFPMAVLIWLMITPMMMNVDFRAVAKVGQRPQGLLVTL
                     FVNWVVKPFSMALFAWIFFRFLFSAWMSPAEADQYIAGAIILAAAPCTAMVFVWSYLT
                     DGDPAYTLVQVSVNDLIMLVLFAPIVGLLVSGASSLTVPLAVLVYSVIGFIVIPLVLG
                     VVIRHWFISQRGKTWFEETLLPSFAPMTIGALLVTLVLIFAFQADNILAKPLHVLLIA
                     IPILLQVYFNASLAYGLMKWVKVPYAVAAPGALIGASNFFELAVATAIALFGPESGAA
                     LATVVGVLVEVPVMLSVCHVCNRTRHWFPSKEATA"
     gene            25126..25596
                     /locus_tag="PK063_11855"
     CDS             25126..25596
                     /locus_tag="PK063_11855"
                     /inference="COORDINATES: protein motif:HMM:NF041414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsI/CadI family heavy metal resistance
                     metalloenzyme"
                     /protein_id="HMZ97793.1"
                     /translation="MKRFHLHMGVEDLDTSIRFYTALFGVPPVKTKSDYAKWMLDDPR
                     INFAISTRAKKGVDHLGIQADGEDELAALRGRIQAGHLPVVNEGKTVCCYALSDKSWI
                     QDPSGLPWETYRTMEDAQLFSGSTDSSEGACCTPLTMAPTNCCEPSEKTAGCCD"
     gene            25596..26024
                     /locus_tag="PK063_11860"
     CDS             25596..26024
                     /locus_tag="PK063_11860"
                     /EC_number="1.20.4.4"
                     /inference="COORDINATES: protein motif:HMM:NF013607.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030612 - arsenate reductase (thioredoxin)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase ArsC"
                     /protein_id="HMZ97794.1"
                     /translation="MESAIVTVLVLCTGNSCRSIMAEALINALRPGRYHAVSAGSHPT
                     GYVHPKSIDTLKRHGIDPGQPKSKSWNEFSHQTFDLVITVCDQAAAEACPLFLGAPTK
                     MHWSTPDPAKATGSEVEIDAAFDQAFLMLKKRVEHLTSTT"
     gene            complement(26414..27547)
                     /locus_tag="PK063_11865"
     CDS             complement(26414..27547)
                     /locus_tag="PK063_11865"
                     /inference="COORDINATES: protein motif:HMM:NF014803.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III PLP-dependent enzyme"
                     /protein_id="HMZ97795.1"
                     /translation="MDQKTLLDLANLHGTPLVVVDHAVLRENYDQFRKHLPRVQVYYA
                     VKANSDPAIVQTFYDVGASFDVASMAEFLIVHEKIKHLPAQQRQDFIWDRIIYANPIK
                     AIETLTQLDQYKPLITYDNHEEVLKIARYAPHSGLVLRLSVPNTGSMVELSSKFGALP
                     GEAVDLIAFAHNNKLVVEGLSFHVGSQCTNVQNYIQALHLAAGIFSEAKTRGFDLKLL
                     DIGGGFPAHYDDSVPAFQSLAKTINAELDRLFPQPIEILAEPGRFLVASAATSVAQII
                     GKAVRGGKLCYYLDDGVYHTYSGVIFDHCQYHLKSFRKDPTQICAVFGPTCDALDTIS
                     LVEQLPDMDRGELVYAENMGAYCGASSTYFNGFPPAKVVHVNQ"
     gene            complement(27625..29085)
                     /locus_tag="PK063_11870"
     CDS             complement(27625..29085)
                     /locus_tag="PK063_11870"
                     /inference="COORDINATES: protein motif:HMM:NF027964.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase NADP-binding
                     domain-containing protein"
                     /protein_id="HMZ97796.1"
                     /translation="MQVFPNRILFVGFGAVARCTLPILLKHIGVDPKRITILDFDPNE
                     AALAPWIKQGVTFVKDRVTPENLGTLLGKHASRGDLLIDLAWNIDCCEIVQWCHDRGV
                     LYINTSVEIWDPYCGVDDKHPTERTLYWRHMNLRRMMASWGEPGPTAVVEHGANPGLI
                     SHFTKHALLDIARQTLADKKFSGEQAERIAHHAQAQEFNHLAHQLGVRVIHCSERDTQ
                     ITDRPKQVDEFVNTWSVEGFREEGTTTAEMGWGTHEKQLPRFAYEHPDGPKSQICLAR
                     MGMNTFVASWVPPDHNIIGMVVRHGEAFSITEKLTVWEGDKAIYRPTVHYAYCPCDAA
                     IASLHELRGSDYRLQSRTRIMTDEIISGADILGVLVMGHPYQSWWCGSHLDIEEARRL
                     VPHQNATTMQVAISVVAACMWMLENPSRGLCVPDNLPHDYILNMSKPYLGKFISAASD
                     WNPLKHYSNFFRGYNQPQLDRSDPWQFKNFLIMEGD"
BASE COUNT         6548 a         7632 c         8585 g         7015 t
ORIGIN      
        1 gtatccggcc atatcatcgg tttgttaaaa gaatatatgc gtgatcttgt cgagcaggcg
       61 cggcaggaat cgcaggctca gcacacgttt ggcttttccg caccgccgta tcagccggat
      121 catgccatcg cggacctgct ctcgatttta gatgatcgga ttgagtcgga aggtctgcaa
      181 gtcggcatgc cgcttgagtt tctgcatgaa atgtggcggc attgtaacga ggcccgcagc
      241 caggtgatgg aacaggtgtg gctggaatcg aatcttggcc cgccgggttc atccaaggat
      301 aggattcgag agttgaccta cgccgcattg atcacccatc tcgaatcgga tgcccaacaa
      361 gaatagccgt gcccggtcgt cattcgtgcc gaggacactc acggttgcca ttttccggtg
      421 atccaataga ccagaatgcc ggccacttcg tcgatggtct gcgtgctgag taagagtgcc
      481 cgggccgtgg ggatgaagtc gaacactgtt ttctcttccc aggcctgttg aggatggtgc
      541 gtggattcgt agccgcaggc aacgggagtg accgtaaagc cctgcttctt aaataagccc
      601 accgcgcggg ggagatgata ggcagcggtg acgagcagga tgtgggccgg gcccaggagg
      661 gccctggtct gcaccgcgtt ttcgtaggtc gttcgggaat tctcctccac atggatgacc
      721 gattccggca caccaaggcg gatcgcccac cgtttcatct cgcgggattc aggcggtccg
      781 gttcggagta cggttgcatc gccgccggcg agcaccatct tgggtgcgag gccctgaaac
      841 cacaattcgg cgccgcaagc ggttcgctgg cgcgaggggt cggaggtttc gtcggccggc
      901 cgcaatgatc ctttgtgaaa gacaccccct gcgaggacga ccacggcgtc gaatttcgct
      961 acggggggta ctgcgaacgg cggatagcgc gcctcaagtt gcgaaatata gaggtgtgaa
     1021 agaaggggag tggcagtaag gaagaggagc agcactgtgc tgaaggccaa gcgtctcacc
     1081 caggtcgttc gtctaggcgt gacaggcaga gaggcgatga ggagggtcaa gagtccggac
     1141 agcacgatcc aggacaaggg atacagaaga tattttgagg ctttatagac accgaaccac
     1201 atcggggtca gatccatagg aactccacgg ttggctcaaa gaatttggct caaagaatgc
     1261 tcagcataca cggaggtgtg acggacacca agtgttcagg aggatggtat ggcagaggga
     1321 cggcactact ggttgatgaa atccgaaccc aacgtctttt cactcgacga tctggcacgc
     1381 gcgccgaagc agataacgtc ttgggacggg gtgcggaact atcaagcgcg taatttcatg
     1441 cgggcgatga aggtcggtga ccaggtgttg ttttatcaca gcaacgctca gccgccttgc
     1501 gtgatgggga tcgccgaagt ggtcaaaacg gcctatcctg atgcgacaca gttcgatccc
     1561 cacgatgtgc attatgatcc ggccagccca gccgaccagc cccgctggga tgtggtggat
     1621 atccggttcg tgcggaagtt tgccgcgcca ctctcattgg atttgctcag agaacaggta
     1681 cgtttaaagg ggatggaatt gcttcgaaag ggatcgcgcc tgtcggtaca gccggtgaag
     1741 ccgtctgagt gggatgaaat ccttcgactc gcgcgtactc atcgtgactg aagcggtacg
     1801 tgaggggcga atggacccct tcaagatctt cattcgtaaa ggaacggcta actgcgagcc
     1861 tttccgtcat ccaaatagcg atgctgccag tcgagccagg catggccaag ctcgtgggca
     1921 agtatgtaac gccgtcgcgt aacgggaagc cgcttgcgga tataaatggt ttttgcttcg
     1981 ttgtcccaaa tcccatccgc attggcatcc tgccggtcca tctccgaatc cgtgacctgc
     2041 cggatcatga tgtgatagcc gaatggaagg accactttgt ttggtattcg caccgtgccc
     2101 ctcactgtct ttcttaaggg cgccttctgc gccggattcc tgctcccgga tagcctaaca
     2161 tatttcctgt ttcgtcttcc ccgattaaaa attcagtttt ttcaggtgct tatgcgtcgt
     2221 tattccgcct ggtgtgtttt ccgctcccct ggtgtcttca ggtgtaaaga gggtgtggag
     2281 gatttcaatt gaacgatcga atggtgtatc atccggccat ggtggataaa ctcctcgctc
     2341 aagaacttgc caagccttac ccgtcggtca tccggattgt gggtgtcaaa atccgtgatc
     2401 gcggcgaagt caagaaattc gacgccgggg aagccacctt agccgtaggc gatcgcgtat
     2461 tggtcgaggt cgggggtgag ctgagctacg gagtcgtgta cggggctcct caggcaacgc
     2521 catttatccc gcccatgcgt gtcatacagt ccattgcccg gaaagccacc gcggaggacg
     2581 cggcaaccat tgatcgctat gaacgactgg cttccgaggg catgagagcc tgccgggaac
     2641 aggccgtcgc gttggggctg aagatgaaac tggtcgaagt cttctgctcc tttcatcggc
     2701 ggcagatgac cttcgtctat acggccgaag atcgtatcga tttccgcgag ttagttcgtc
     2761 tgctcgcgcg ccggttcggc gggcggatcg aaatgcgtca ggtgggcgtt agggatgagg
     2821 ccagccgatt gggcggaatc gacacgtgcg ggctcgtctt gtgctgtgcc gcatttctga
     2881 cagaggtcaa accggtgacc gtgaaacaag cccgcgtcat gggtcttccc gtggatgacc
     2941 ccaaattact gggagtctgt ggccgcctca agtgttgtct cttgttcgaa gctatggaaa
     3001 gtcagccgtc ctcctcgtca tccaaatcgt ctgcactgat aaatcccgct cgtacccgtt
     3061 tggcgtcttc ctagttcccc atccgtttcg gccagatctc tgtcgcatcg cgctgcgaag
     3121 cctgcttttg cgacctgctg gtgaaagcct cgtcattgta gtatgaaaga gtataatgac
     3181 catgaggtga cggatgcctc aggtactggt actcggatcc gggaaaatcg gctctctcat
     3241 tgccgggctg ctgtcggcca agggacagta tcaggtgcat ctggccgatc tcacgctgga
     3301 tgcgcccaaa cgattgatcg atgacctggc gctgacgacg gttactccct gcgcgctgga
     3361 tgtgcggcgg cctgattcgg tcgttgccta tgtgactgcc caccgttttg acgcggtgat
     3421 ctcctgtctc ccgtattttt ataatccggc ggtcgctgaa attgcgcgag cccatcatct
     3481 ccactatttt gacctcaccg aagacgtggc cgtaaccgga tgcgtcaaga ggatcagcga
     3541 aggcgctgat cacgcgtttc tccctcagtg cgggttggct cccggtttta tcagcatcgt
     3601 cacgaatgat ctcatcggcc atttcgaatc catcgaccat gtgaagatgc gcgtgggcgc
     3661 attgccggtc cacccgagta atgccttgaa gtactccctg acgtggtcga ccgacgggtt
     3721 gctcaatgaa tatggaaatg tctgtgtcgg aattgaacgg ggggaagagg ttcacctgcg
     3781 gcctttggaa gggtacgaga cgattgaatt ggatggtctg ctctatgaag ccttcaatac
     3841 gtcgggtggg ctgggcactc tcgcggacac ctatcgcggc cgggtccgga cgatgaacta
     3901 caagaccctg cggtaccccg gccattgcga aaaaattcaa tttctcatga acgatctcaa
     3961 actgaatgaa gaccgtgaga ccctcaagcg tattctcgag cgggcgattc cgcagacgca
     4021 tcaggatgtg gtgttgatgt acgccgcggt cacaggaacc cggcagggtg aattatttga
     4081 agagacctac gtgaagaaag tctaccctcg gatgatgctc gggcgcactt ggtcggcgat
     4141 tcaggtgacc accgcgtcat ccctctgttg tgtgcttgat ctggttctgg ctcagccatc
     4201 cgcctatcga ggattcatcc ggcaggaaca tttccccttg cgcgatgtgg tgaacaatcg
     4261 gttcggggac tgtttccgtt cctagggcaa taatgacgac agaagaactc tttacacggt
     4321 tgggtttggc ccgggaacaa tcgggtgggg gcggttcttc ctcgacatgg acacgtacga
     4381 ctccggcagg agtggtggaa tcccggaatc cctcgacggg tcagaccctg ggccgagtgt
     4441 acggttgcac ggatgatgag tacgatgccc tggtgatcgg cttgcagcac atgcagaagg
     4501 tttggcggac ggtgccggct cctaagcggg gcgaggtcat tcgtcggatt gctgaggcgc
     4561 tcagagaaca gaaggatgct ctcggcagtc tgattgccct cgaagtgggg aagattaaag
     4621 ccgagggcga tggcgaagtg caagagatga tcgacatggc ggatttcgcc gtggggcttt
     4681 cgcgcatgtt gtacgggtac accatgcatt cggagcggcc acagcaccgg atgtacgaac
     4741 aatggcatcc gttgggcgtc ataggcgtga ttacggcgtt caattttccc gtcgcggtct
     4801 gggcttggaa tgcattcatc gcagccgtga caggaaatac ggtgttgtgg aaaccctcgc
     4861 ccaaggcgcc gctctgcgca gtggccatcc agcaactctg caatcgcgtc ttggaagacg
     4921 ccggatatcc gggtgtcttt gcactctgta cgacagatcg tgttgaactg gctgagcgcc
     4981 tggttcgaga tgaacggctt ccgctgatct ccttcaccgg ttctgtgccg gtgggaaggc
     5041 aagtggcgga ggtggttggg cgtcgcctgg gccgcagtct gctggaattg agcggcaata
     5101 atgccatcat agtcgatgag accgcggacc tcgaattggc cacgagagcg attgtcttcg
     5161 gcgcagtcgg cactgccgga cagcgctgca ctagtaccag acgagtcatc gtgcaggatt
     5221 cccagtacga caagctggtg tcgcgcctcg tctctgccta tgggcaggta accatcgggg
     5281 atccgcttca accgaatgtc atgatggggc cgctgatcga tcgcgaagcc gtggcgcggt
     5341 atcagtcggc actcgaggac gtgagacaag ctggtggtga ggtgctctgt ggagggcgcg
     5401 tcttatctcg tccggggtat tacgtcgagc cgacgattgt gcgagcccag aatcattgga
     5461 agattgttca gcaggaaacg tttgcgccga tcttgtatgt catgacctat cggacgctcg
     5521 atgaggcgat cgatatgcag aatgccgtgc cgcaaggatt atcgtccgcg ctgtttacca
     5581 ctcaccttca tcatagcgag gccttcctgt cggcctcggg cagcgattgc ggtattgcca
     5641 acatcaacat cggtacctcc ggagcggaga tcggcggggc attcggggga gagaagcaca
     5701 caggcggcgg gcgtgaagcg ggatctgacg cgtggaaggc ctatatgcgg cgtcagacca
     5761 cgacgatcaa ctgggggact gaattacagc tggcgcaggg gattaccttt gggcgatcgg
     5821 aaggaggaaa ccatggggca agccgctgag cttgatgccg tgattgctcg tatgacggcg
     5881 gatttccttg cacagaatac cgcggccgga atgcttcgtc gcgcactgga cgacgtcggt
     5941 gttggatttg tgccggtcat ggaccatttg acgattcgga ccatgaacat tgaccagcgc
     6001 gcggaggaat tcgtcgccct tggctacgga tacgatgaaa cgatttacta cgacgattgg
     6061 tatgccaagg tcttcagaaa agccggatat ccggcactgt ttgtcgacca ggcgtacccg
     6121 gatgctcgcg gacataccag catcattccc cgttgggtgg ataagtttgg tgatcgtgtg
     6181 ttccatcacg tagctgtccg ggtcgaggac attgagcaag cgattctgaa actgaaatcg
     6241 aagggcgtgg tctttgccgg agaaatcgtc ggtgcccggg gaggaccgct tcggcagatc
     6301 tttactgcgc ccgagatgat tgacgggcaa ccgttttcgg tcttggaact cgccgaacgg
     6361 catcagggct atcagggctt tcttcctcca caagccgata gtctcatgcg ctctaccgtg
     6421 cgctagatac tctgtgggtt cccttcctca tcgacgctgc cgcgcgcatc ttggcggcgt
     6481 ctctctttgc agaatggcta attctgcgta caatggccag cgcgatatga gtagttcatc
     6541 gcttccaaca cctgaaatcc atacaggagg tcatctctat ggtgcgaacg gttttgccgc
     6601 tctgcttcat ccttgtcctg ttgtgtgtcg ctacattcgg gattggcgag agtctggtgg
     6661 gtgcctcacc ttccggtcac gcgcctcatg ggaccgtaac catcgacggc atcacggtac
     6721 ctgatatcgg cccactgccg actgcagttc cgattccctc ttcaaacgtc aattatgccg
     6781 ctaagattga gctgggaaaa cagttgtatt ttgacggacg attatccaaa aacaacgcga
     6841 tctcctgcgc gttctgtcat aacccgggaa cgggatttgc ggactcccgt cagacgtcga
     6901 tcggcgtcgg tggtggaatt ggtggtcgcc aatcgccgac cgtctacaat acggggttta
     6961 atcatgtgca attctgggac ggccgagcgc ggtcgctgga agaacaagcg atcgggccga
     7021 tccacaaccc cgtggaaatg gcggagacgc atgaacacgt cgttgccaag ttggggaaga
     7081 tcaagggcta tcaacaagaa ttccgcgccg tcttcgggac ggaggtcaat ctgcagggga
     7141 ttgccgaggc cattgctgcc tatgagcgta cagtgctctc cacgaattcc gcctttgata
     7201 aatatgtgct cggtgatgta aaggccatgg atgaagctgc tgctcgaggg ttaggcctct
     7261 ttaagggaaa ggcccggtgt attctgtgtc acaatgggcc gaactttacc gacaaccagt
     7321 ttcacaatct gggggttcct caagtcgggc cgatgaagga agacctggga cggtacaacg
     7381 tcaccagggc agacaaagac aaaggagcgt tcaaaacgcc gactctccgc agcgttaccg
     7441 agactgctcc gtatatgcac gatggcgcct tcaagacctt ggaggaagtc gtcgactttt
     7501 tagatcaggg aggcggcagc aatcccagac tgagtccgtt gatgcgtccg ctcggtctca
     7561 ccacagagga gaaagccgat ctggtgatgt tcctgaaggc gttgacggga gagccgataa
     7621 agttcagcat gccgcagttg ccgaaataaa tcgcgaatcc tttcggacag ctgtgactct
     7681 tacgggcaga gaggcaaaag ggatcggtct gtcgataaaa cccatccatg caatccaccc
     7741 caaccagagg aggccttcta tgtttcgaca actttgcgtg cttggtgcga gcacgctcgc
     7801 gctcgccatg ggcggaccag cacttgccgc ggatatgaag ccgggtccgg ccgacggatt
     7861 cgacattcat gtgatggccc cgcataagat ggaggacgga tcggtggccg gtcccttcca
     7921 ccactattgc aaagccatca agccagaggt cttgcagtgt ttgttgttcg aatccacggc
     7981 gccgaatgcc gtgttaaccg atgtggaata cttcgtggcg aaacctgtct ctcggtcagc
     8041 ggtgccgctg gatgtgtgga ataaattcta tcacgatcat gaggtcgaaa ttgccaccgg
     8101 tcgcgtgcaa gtgctggaca tgccggatgc gcaggcgaaa gaagtggctg ccgcggcagc
     8161 caaaacagat ggcattatct tccacttatg gccaaaaggt gcaaaagctc ctgatggatc
     8221 ggtcggtcat ccgacgtctg tggggcataa gccgcggacg gaataacatc gcgttcatga
     8281 acgatcgacg atctgtcgac ctatggtaag gaggccatta tgcgaagtgc gattgcaatg
     8341 atcggattat gcgcggctgc cctcacggcg accggctgtg cggaaacgtc tcatgacatg
     8401 aagtccacgg ctgctgccgc cccggccgca acagcggcga aagccatgcc gacaccggct
     8461 caagggtata ccattcacgt gatggccccc cataagtttg aagacggaac ggtacacggt
     8521 ccctatcatc attactgtaa gcccatctcc ccggagatct tacagtgctt gctatttgaa
     8581 tccacggact cgaatgcctt gttgacggac attgagtatt tcgtggctaa atccgtctcg
     8641 cgggcacatg tgccattgga aacctggaat aagtactatc acgatcacga agtggagatt
     8701 gcaacgggcc gcgtccaaat cctggatatg ccggatgcgc aggccaagga agtcgctgcg
     8761 gtcgcggcta agactgacgg catcattttc catctctggc cggatggggc gaaggcgccg
     8821 aacggggaag tgggacatcc gcagtcggtt ggccataagc atcggacgga gtaagtaggt
     8881 tgtgtttacg caccgggcgg agggggagcg ttcggcatcc tctccgcccg tgttgttttg
     8941 tagagaggaa tagctgtgat gaagtccgta tccctctttc tttatgcctg gacggtagtc
     9001 ggcgtagggg ccatagcctg gtccgcggat tccgaggtgt tgcgtcctcg cgtgccggtc
     9061 gatcagatcg agtcggcgcg tgcagtgacg aatccatttc cggtgacgcc ggaaatgcgc
     9121 gagaaaggaa aggccctgtt tgagggaaag gccttttgtc gcgcctgtca cggggccgat
     9181 gggaagggcc tgggtctgga cctggactat tctaccttta agggaccgct gccacgaaat
     9241 ttcacggaca agatgtggca acaggcgcgc acggacggcg aattgttctg gatactcaaa
     9301 aatgggagtc ccggaacaga tatggcatcg tttattccgt tggttctgac cgaagaagaa
     9361 gcctggcaag tgttgatgta tgtgcgttca ttcggtggga gatgacagat cgtctcggct
     9421 cagtcgggat tgtgaagagt cgtcgtggga tgcgggaacc gggtaacctg ttctgttgtg
     9481 aaatatatac ggatcgtgag aatggcccag agcaaggttt cgttggaaaa tcaacgacga
     9541 taagcggtta agaattgatc cagacggtga cgctctgaag cggggagccg aagaaattcg
     9601 atgccgaaat agtgcctgcg gacccagcgg actgcggcca ggtctatgac caatgcatgg
     9661 tcgttgtccg gcaggaggag tcctactgtc aggtagctgc cctccatcac cgtcccctca
     9721 cattctagaa ggcatccatg tggtgagaga ttgagaacag tcccttctcc aatgaatctg
     9781 gccccggcga acatgatggg aaagactatg cccagccggt ctcgagatcg ttgaaaggaa
     9841 agggtggttt gtgacggaga ggggtggagt cgtggcgttc gtggtgatga aagatgtgac
     9901 tgcatggagg gcattgtagt gcctgcaatg gagttcctca catcccacct tcgggggatg
     9961 tgccggttgg ttcttgtgta aggaatttgc cacgaacgtt gaggaaagaa tcaatggcgg
    10021 ctggcggcat agaaacgatg actgcaggat cgacatcgcc agggaaagcg gcccagcaaa
    10081 tgccataaga aatcgcgcca ccctcggcgt ccagagcgac gtattactcc gggacacaga
    10141 gggcagcaat gcgagaaggc agtgggagtt tcaacggcca taggtcttac tgtgaagcgc
    10201 gctctcagcg tagtgcattg acggtaaaca ggtcgacgtt atgctgggcg cagttacaca
    10261 ttgtctctgc ctgcgctgca tggaaaaagt catcactcct gccaccacac caaacgaatc
    10321 acataaattc ctgcgatata agttgctgca atgataatcg cccagatcat gatcccctcc
    10381 tgattctttc gcggcattct gccgcatccg tgatgcaacg ataggatgac tagcaactcg
    10441 cgtaccatca cgcgaccaac ttgcggctgc gtgtgaatgt cgaaatttct tcgtgttggc
    10501 ggttcgtgtc agcgaacaga ggttttcgtc gtcttgaatt gagatgacgc tgtatccaat
    10561 tcgataagag tgaatcggtt tggataccgg gaaaagccca gatggcgaag ccactacttg
    10621 gcttgttgtg atttgatgga actggcgatc agccgcgggg aaggagcccg ttcatgaggg
    10681 aggcgtcggc agggccgcgg agtaaaggga cgtagcttcc tgcttctgct cggtggttcg
    10741 attggcgcat cagggttttg acgcgcggga ggaggcgttg cgagctcgtt gctcgacggc
    10801 caaggcagag gccgtgatgg cgtaatcgca ctgtccgcag tgcaaaaagc ctccagtcgg
    10861 gaccaaactg tgatgtcggc atcgggggca gtcataaatc ttcattggtg acctcctgtg
    10921 tcagtgcaag gacggatggt gagggtatcg tgctgatcca aagggcaatg cggaccctgc
    10981 gcgtgatgtc cccacgatca agaatcgcgt gcggtgattt cgccggggat cttcgtgggg
    11041 tagcggatat ggaacgcctt ccgatctccg caattgacgc atcgccaccg gccttctgga
    11101 tcataaaaat cgtttgatgg ttcgattgcc atatagcctc cgcatcggga acagggcatc
    11161 gttcaatctc cttccgcagc atttgtggga gccgatgaat ggagaggatt tacggacgga
    11221 ttgcgccctc tccattcatc gggtccatca ctacgctact cctccggcct gatgggcatg
    11281 gtcagcgccg tatcatcttc acgcgcggga ctttatcaac cgttcagtcc tgggtgcgct
    11341 gcagattgaa gcagggcagc tctcgatcat agtatcgcct gtcagccgcg ttaggaatgt
    11401 ttactttcct gaacgaggaa gacattcagt gccagcatat gaggtcgatc gaggtaatcg
    11461 ttctgccagc acaggagacg tttgtctgta gagcgagcct actaagaacg gaaaggcttc
    11521 tttcatcagt tccgtcgaag cttacgacaa ccgtttcgtc gaaaggggat agtcttggga
    11581 gctgggaatt tctgcaagaa tagctcgggg aaagcatcgg tggttgaaag cgctgttgaa
    11641 acgtacaatc tgagattccg cagagttgct tatagattgg ggggcctggc agaatacgtg
    11701 cctagatggc cacgtctaca tcgtctctca cacaatgccc tgatgtactc ataccattaa
    11761 tggccaacat tctggcctcg aggccgatta tcgatcgcct gccaaaggac aggcgggtaa
    11821 ggcgagcaca agtccggccc tctaccacgc attgtattca tcaacagaga gtggcgctga
    11881 cgcgcaccga gtatgacgag ctcatgatcc tgttcaatag aactatgggg caagcgttta
    11941 cggtaccact tcagccgtct cagaaaatat gcacggtgac ctttgccact ccgcctctcc
    12001 tcagcgaacg actggtgtcg ataagtcttc gaaaactgac ctccgacagg gctaagttta
    12061 ggctcgacta attttgtgaa aatgctcggt tgcggagctt cttgcctctt ctcggtagag
    12121 tggtatgcca ttcctaatgg cttgtcatcg gcagaaatga tacagcgatt gaaatcgtaa
    12181 tcagggcaat aataatccac tcgagcactt ccatccgttg agtcgtcgca cggtcggaca
    12241 tctttccata aatgctatcc agcgtttgta gttttctgat gatgctcgcg tcccaggcct
    12301 caaggtgaaa ccgctgagag gccaagcgat agaccctggc cagatactga tcgcccagca
    12361 acttcagggt attggccaca cgttcgaaga gcacggcact gtccacctgt agttgtccga
    12421 tttgtgtaag agcagcctca tgggaaccag gtagccaaga tgtaactcga gcctttcgtg
    12481 tgagcgcaac atacccctga tccagtgcct gatcgagttg ctcatctagc gtacgcattt
    12541 ccagcagctc tacatttacg aactccaata ctgcccgaac gtcgtccata tcttctccga
    12601 acacaatggc agcattccaa tcgatgagag cggtgtcgtc tcgactgaat gagatacgac
    12661 aagatgtcgc ttcgcgaatc tcctgatcgg atagacgcgt tcgttcgctg cgcaggacat
    12721 gtgcaaacat cggttcaaag ggagtgccca acgcttgaat ggcagatggg ctgcaatgct
    12781 cgacggaaaa caccaggtag tcttctacct cgggcgagac tgacggacgg tcaatggcca
    12841 atcgaatgtc acgcaccaac tggtccaagc ggtgacgcga gtcggcgagc agcctctcat
    12901 tttcgtacag gctttcgctc aagctcagga ggccttcgaa aggtccattg ataggaatgc
    12961 ggtaaatgac agtgacggca ccgaagtcat agagcatcac ctccacggct tcgctcgatc
    13021 gatagtcacc gaagtcgaga gacgcggtct cctgaatcag gcgcaatggc gctggacgat
    13081 actcgaaata atgtggagct cgtgctttgt ggcgcatgcg gccgcgttcc ttgatggccg
    13141 tcacatgtct ctcagcttcg tcaagattga tggccaatcc aatgtcatag gcgaacaagg
    13201 cgtaacaggt tccctgttca atcaccaacg agggagcatc cgcggagggc atgagactat
    13261 ctcctttgat acaccgatga tgcggctatt tgtgctcgta ctgcaagtca gccaatgttg
    13321 aaggatgctg atctgcctga tgtgaggctc gccatcatgc gtcctacgta ttacaagacc
    13381 gtaaggaagc tgtaaactct gtatcaatca ggctcaggcg tattgcatgg aaggattggt
    13441 atccgtatga atgagcaagc ctatgccgac aatcaaagca atcatcttcg atttcgatgg
    13501 cgtgctattc gacacagagg cgatccactt tgccgtattc cgagaggtgc tacggtcgga
    13561 gggaatcccg ttgacgttaa gtcgatacca cgcagcctac gtcggtctct ccgatgaggc
    13621 ttgtttccgc gcaatcttga atgaccatag aattgtggtc ccgaaggagg atatacaaca
    13681 attagttcgt cgcaaaacgg atctcgtgca acgggcattc cgtgcatctc tgccgcgtgt
    13741 atcgggcgtc tcggaatttg tcagcgatgc atccatgcgt taccggttgg ccatcgcttc
    13801 gggcgcactt cttcaggaaa ttgtgttgtg tttgaagcta gggagcatgc ttactatgtt
    13861 cgagcacatt acggcggccg gggatgttcg ggaaggcaag cccaacccgg ccccctatct
    13921 gcatgctctc cacgccttgc acggacgatc gccgatagca gccaatgaat gtctggttat
    13981 cgaagatacg ccacatggag tggaggctgc ccacaaggcc ggcatgagat gcgtcgcagt
    14041 gaccacgacc cttcctgctg atcgactcgc acaggctgat ctagtcgttc cttcacttca
    14101 cgccctacga cttgaggatc tgactgtgca gcttccttga gagatttccg gtcttgccga
    14161 cagcagcacg gtgttacgca aagtttccga cgacatgacg gaatcgtaac acacactccc
    14221 taagatacaa tctccgtcag gcatcagttc gagagatgga tcactcggat cttcttgatg
    14281 agtcgaacga ctgccctctc cgcaaattca tcgccctatg ccgtcgaatc ccgtcatgta
    14341 attgagcggg aggcggtgga attcctcgcc aactctgtca cgttgccttt ttcctcaagc
    14401 gatatcacgg ctggatcaga aagcgagttg caggcggcgg tcttgggccg atcagcagac
    14461 gtggacctgg cgcaaacaat tcacagatca aactatttga agaatattcg ggatcgaacg
    14521 gagacggggg agagtccgcg tatcgtcatc caacagctgc aggagtttct caacgattcc
    14581 caatcgaccg tctgggaaaa ctcctgggtt cggtttcctc gaaacatgct taataaggag
    14641 gccaatcagc tgttggcgtg tgatctgcga gcaaataggc gcgatccgaa aggaacgcct
    14701 cgtactgata ttgaccgttt tttggtcacg gaacaaggag aggaatgggt cagagtgccg
    14761 gtcagctatg ttctgcggct cgcgcttgcc caagtcattg gagcgatcga gtccgatgtt
    14821 ccaatgctgg cgaaagaagg gcgtcgactg ttggaccact ttttgaacga taacagttca
    14881 ccggagacct tttccttcta tgtgtccggg atggatccgg caagagggat ggggaaagcc
    14941 atcgcgcatg aaacagcgat ccgctttctc ctcacacaat tacttgttca gtatgcaaat
    15001 cgagcattcg gactggatga aaccgggcaa catgcgattg tctatgcttc gccacacccg
    15061 cctgtgcgtc agcgccgcct caatggactc atttcggatt cgttctatcg ggaattgttt
    15121 gtgaatccct gtttgtccgg ttgggatcag ggcgaagaca aatcgcgcta tatgggactg
    15181 tgccatgaag tattgtctcg gagccaactc aatgccgtcg tgcggttgaa agacgcggga
    15241 attattactc gcaacctcgt ggtgttgccg gcaacttcca acattagtct ggccaataac
    15301 ggtacacacc tcagtctggg tagccgcatg ttgaccgaaa cactgcaagc gaatggcaag
    15361 cgatttaccg cggttcatga aaaggtcctc ggcgatcttg tgatcaaaat cgtcgaacat
    15421 tttctgccct tgtttgtagg gacctatagt gctgctccgt atcgcatgaa ctttcgagac
    15481 tttcaccccg aaactgcgtt gggattttta ccgcacgaac tggactttgc tcacctgcgc
    15541 atgctgtggc ggcggtggaa aaagaaggcc ggtctttcgg tatttggccg gtccatcaca
    15601 ccgctagggc caccatggtt ggatcgagcc atcagtttta tctttaatct ccgtggcgac
    15661 tgtctgccag atttccggtt aatcgactac ctcgtgtgcc tgttgtctac ggaacaaagc
    15721 ccggcgctgg acggcatccc aggcaacgat cttcgactga aacgagacct cggtcaactg
    15781 ggggtattcg acgagcgcat gtcgctctat ctactgtaca agttgcgcgc tcaatcagta
    15841 atggggtttt caggttttga aggccgacac tacagcctct tttggaacca cacagacgac
    15901 ttcgcgcaag cggcaagcat gcaggctctc gtgacagccc tggcgtttca gtatatcgca
    15961 aggggtgagg tgagccatga ggatatcccc gacgatccca tgactgagag cgaacgccga
    16021 caatacctgt tcgcgacggc ggttggggta gggacagtga atgtgcgaga ggcaggcccc
    16081 aatcgatttc tcactcggat tctgatgaag acccacaaga caagagcgag ccggcgttat
    16141 gcggggcacc tgcgagttcg ttgtgaggac taccgtatgg cactggtagc tatgctcgag
    16201 gaggatgcct cggaccttat cgagtcgttt caaatgcagg aatgtatgcg aagtttacgc
    16261 gatcggctgt cgaaccagga ctccagtact gctgggaaac tcacacacgg catcctgaac
    16321 tctgtgggaa gtccaagcgc ctttgatctg tcgggcgagg agtttgccct agcggcggag
    16381 ggctactacc gtcgagagtt gagggcgcaa tacctgcgcg aagcctgcga gtctgtacga
    16441 gaggaattgt gcgccattga tcagggcgtt tctgaacagg ccacgcaata tcgcggcctc
    16501 gttaccgcca tgatcggcac gcgttcggcg gtggacgcgt ttacagaaga gcagccgcgc
    16561 ctgttggcgg agactgccga tgccaagacc ctccagcgtt gtttggggct ttgtattatg
    16621 agtatcgccc acgctcggat ctctgcgggg cgaacagagg agcagccgct cgcttcatga
    16681 gtatgccgca tcagtacatc gaacgcgaca gcaatctggt tgtgactgaa cggttttgtg
    16741 gggatcaatg gctcaactgg gcctaccgtg ccttgtggga aaatgcaaat tggttcatga
    16801 aggcgctcac ttcacgcaga accacccaag ccctcggatt ctttaactat gataggccgt
    16861 tcacttccac ccaagcagcc gtggccaggt ttgctcgagc tctgtcagtc gacctgtccg
    16921 aatgcctgga tagctcggat cgcctcaaca caccgcgccg tctgttccag cggcggctgc
    16981 ggtactggca agtacggcca atggatgatg atcccagggc cattgtttct cctgcagatg
    17041 cccgccttct gatcggttcc ttcgccgacg attcctcgat ctttcttaaa ggaaagtttt
    17101 ttgattacga cgaactgctc ggcaaacatc ggccacaatg gcgccggctg ttccagcgag
    17161 gcgattgggc aattttccgt ctgacgcccg ataagtacca ttacaatcac tgtcccgtct
    17221 cagggcgcgt cgttgattgt tatgagatta acgggcgcta tcattcatgt aaccccggtg
    17281 ctgtggtcgt cgcagcaacg ccctactcga agaacagacg catcgtcacc ataatcgata
    17341 cggatgttcc gggagggact cgtgtgggac aggtggccat gatcgaagtg gttgccctca
    17401 tgattggtca gattgatcaa tgctactcct ccgtcgccta cgacgatcca cagaccatgc
    17461 agattggcat gatgctcaag aagggctgtc caaagagttt gtaccgccca ggaagctcga
    17521 ccgatgtatt gttgtttgag cctggccggc tctccttcag tgaagacctg ctacggaatc
    17581 gatttcgacc tggggtacag agccggtttt cagaagggtt tggccgtccg ctcatcgaga
    17641 cagatgttaa ggtgcgttcg acgatcgcat ggcggttaga aagggggatc gatgggcgat
    17701 agtacgtctg tcattgcgct tctgatcgtt ttgtatgggt tgctgttctg gtgggccttt
    17761 cgaacgttgc cacaggagag ctggcagttt gtggcctcta tgccgcgaat gaaactgtct
    17821 gacggtcgct gggtagggac caacctgact tactatgggg cctggaccgc aactgcagtg
    17881 gtctttgccg tggcgatggc aatcgtctta atgcaaagcg tcgcagtggc gcttgatgcc
    17941 attgctctgt tagcagttgt cttgctcgga ctatgcgtgc cagcctcaaa aattctggct
    18001 cgtctcatag aaggcaaagc gaatacgttc accgtcggcg gcgcttccat gctcggcttg
    18061 ttcttagcgc ccatgattat cgacggaatt aatctggtgc tgaactggac cgggaaggga
    18121 gcacttccag ccgctgcggt cctggcagcg ttgagtgtcg cctatgcatt tggcgaaggg
    18181 acggggaggc tggcctgcct cagctttggg tgttgttatg gggttcctct gcaggaaagt
    18241 ggtccacggc tgtcggcatg gttccagcag tatcacatcg cattcgtagg cagaacgaag
    18301 aaagctgcct atgagggtga tctggaagct gttccactca tccccattca agcactgaca
    18361 gccgtcatgt cagtcggtgc aggcatcacc ggagtgtggc tatttttaca agggcacatg
    18421 gccgctagct tcttgagcac tatcgcgatc acacaactct ggcgagtagc atccgaatac
    18481 cttcgggcgg attttcgtgg cgttgggacg ctctcgtggt atcaaatcct ctcgctatta
    18541 ggcgtgctct atgctttcgt cctcacattt tggctggata ccttctcccc cagcgttccg
    18601 aatatgaggt tgggacttcg tgacatttgg agtcccggga tcattctcgc cctggaggcg
    18661 ctgtggcttg gcatcttttt cttcaccggg cggagccgag tcactgcatc gacgttgacc
    18721 atgcgagtgc tgagggatcg gatttgacaa ggcgagtgcc gcgtagcccc gtatacgtgt
    18781 tgttagcggt gctggtctgt ctcacgtttc ctcctcaggc tagttcagag gaggaaactc
    18841 ttccagcgga ctatccggcg tcgttggaac gcgttctctc cgtccagctg tcccggctct
    18901 ccacagaagg ccccactcta gatcgattgc tccagttatc agagttgtat atgaatattg
    18961 cagatgatct gttcaatgat gaggagcgaa agcagctggc gtacgaagcc gcatcggcaa
    19021 tggcgaagcg agccctcacc atagatgagc ggagcgctca tgctcatttt ctgtatgcgg
    19081 cctcgctggg tagcggggag cgcctcaaag ggctttcgaa aggtgggctt gtcttaggtg
    19141 agctcaagca gcatatccga cgcgccatcg agctgaatcc gacccacgca caggcgttgc
    19201 aaatgatggg aggcttgtgc gctgagctac cctggctgct aggaggaagt gataaagacg
    19261 ccgaattgta cttaaagcgg gccattgcag cggatggaag gtttacgaat gcccacctca
    19321 ttttggctcg gttgctcatg aggcaaggcc gtttggccga ggctcgtgaa catattgaat
    19381 cggtcctgca tgcggaacac ccgcattatc cctatgcctg gaaacataca tttcgacccg
    19441 aggcagaacg gttactcaat ctgctttcaa aatagtaagt aaaagattgt tcatgtctcc
    19501 tgtcctggca aaagagatgt tcaggctcct tcagcggggc agaacataag gccagtatct
    19561 tggatcgaga taacgaccac tccgcgcccc cttccgcgaa gctcgtcagg tctctacgtc
    19621 atttgcccaa tagttaaacg tgcccatacg gcaggttaat aaaaccgtaa cagcgtaccc
    19681 ctatactcgc cagctcacgt atcttttccc aacaagggag acaattgcat ctatgggacc
    19741 tgcgcttcat accaccactg cagcacatcc attgaccgtc cagccttcga ggtctcttgc
    19801 gtcgttcgga ttctttgcct tcgtgatcct gctctttctg gggactctct atacggttga
    19861 gcagctatcc tttgaactca tggcggtcaa gcaatcatcc gcatggccat ttatcctgct
    19921 cggtgttgcc ttagtcattg cattgggatt tgagttcgtc aatggttttc acgacacggc
    19981 caatgcagtc gcgacagtca tttatacgca ctcgctgcct cctcatgcgg ctgtcatttg
    20041 gtccggactc tggaatttta tcggggtcat gatggcttcg ggcgctgtcg cgtttggtat
    20101 cgtatcgttg ctccctgttg agttaatcct ccaagtcagt gcaggcgccg gattcgccat
    20161 ggtgtttgcg ctattgattg ctgccattat ttggaatctg ggtacctggt atatcggcct
    20221 tccctcttca agttctcaca ctctcattgg ctcggtgatc ggggtggggc tcatgaatca
    20281 attgatggcc gggagcgcag aggctacgag tggagtggac tgggcccaag cgttgaacat
    20341 tggaaaatcc ctcttagttt ccctgctgtt tggtttttcc gtggccgcat tcttattact
    20401 tgtggcaatg cgtgccattc caatcgcaag tctctaccgt gcccctcagg gcaagactcc
    20461 tccccccttg tggatacgtg gcattttgat tcttacgtgc accggagtga gtttcgctca
    20521 tggctcaaat gatgggcaaa aggggatggg attgatcatg ctcattttga ttgggacggt
    20581 tcctaccgtg tatgcgctca atcggactgt ggacatttcc tataccccgg ccttcgtaga
    20641 aacatcgaga caagcggaac ggacattgga caggtataca catggacagc cagcaccaac
    20701 cgacccacgg catgaagtgg gacagtactt gaggtctcgt caactcatgc cagagaccat
    20761 tccggctcta cgggccctta gtgcagaggt gcgcgaaggg atttcagcct ttggatcagt
    20821 ggcacaggtc ccggatgaac aaaccggcaa tctgcggaac gatatgcatc tcatcacgga
    20881 agcgcttcgt cgcatggaga agcagcatga tcctccgttg tctgcgccag acctaaagat
    20941 cttgaaagag tatcgctcca ctttagatac agcgacaaaa tttatcccca catgggttaa
    21001 ggctgcggtg gcattagcgc tggggctggg tacgatgatc ggatggagac ggatcgtggt
    21061 cacagttggc gagaaaatcg gtaaggccca tcttacctac ggacagggcg catgcgccga
    21121 aatggtcgcg atgggcacaa ttggtgccgc ggacatgctt ggtttgcctg tgagtactac
    21181 gcaagtcctc tcttcaggtg tggctggaac gatggcggcg aatcaatcgg gactacagtg
    21241 gaataccgtg cgcaatctcc taatggcttg ggttcttaca ttgcccgctt ctatcgtgtt
    21301 gtcggggagt ctcttttgga tttttaggca cctcgtctag tcacgggatg ctaagtgggg
    21361 cttgggaaga tgttgagcgc atttgtcttg gaagagggtc gagtcatcca ggctcagatt
    21421 gacgacaaag acgatttgac tcgcaaggac ttggtttggg tggatttggc atacccgagt
    21481 gaagaggagc gcgagttggt gcagtctgtg ttcccactcg aattgcctga tgatgaggag
    21541 ttacaagacc tcgaggcgag cgcacgctat taccaagatc agcacggcat acacattcga
    21601 tcaacgtttg tccaaaccgc tgacgatgtg gcttcaatcg tgaacatgtc cttcagtctg
    21661 catcagggcc gattgttgac agtccacgac gatgacctga gtttactacg actctttcgg
    21721 atgcaggcgc gatcgagtag gggaatggtg cgtgacgccg cagacatctt gttgagttgt
    21781 tacgaactcg gggtggagcg agatgcggat gttcttgaac gaatctatac ggctttggat
    21841 gaagtaggga cagttgtgtt gagccggaaa aaagagatca cctctcgaat catgcgcgat
    21901 aacgtcgagc gcatcgccgc gcaggaggat ctcaattcaa aagtacgatt ggatttgatc
    21961 gataacagaa gggcgctctc attcctgctt cgaagccgtg tgctttcacc cgaccaagcc
    22021 cagcgagtca aaggggtgtt gcgtgatatc gattcgttaa atgggcacac aggattcatt
    22081 ttcgacaaaa taaacttttt gatggatgcg ctgttaggca tgatcaatct cgagcaaaac
    22141 aaaatcatca aaattttctc tattgctgca gtggtctttc tgcctcccac ccttgtggca
    22201 agcatctacg gaatgaattt tgagcatatg ccggaaatga aatggccttt gggctatccg
    22261 atggcgcttc ttttgatggt ctttgccggc ggcgcgccat atctgtactt taggcaaaag
    22321 ggatggttgg actgaacagc atgtaaccac gctcattcga ggaaagagga gaacgatgaa
    22381 ttcccagcag aacaacaaac ccagtcgccc aggacgaaaa ggcgcactcg caaaactatc
    22441 agaaccgcaa gtgggagatg ctccaccaaa gctaaaatca aagccaagca aacgccctat
    22501 gctgcacgat gcctcgacag tacctcctca gaagcacgtg ctgacacaag aagagtttag
    22561 agcacgagtg tcacgcaaag cctttgagct ctatgaaatt cgccgatcgg ttactgaagt
    22621 ggatgattgg attgcggccg agcgtctggt gaaagttgaa ttactcagtg aagaacgagg
    22681 ggcaggatca gtctagattt tacattctga tcattattct gctcattatg agtggatcgg
    22741 ccattgggat tgcatatcgg cgtgagcaga ttgatttgtg cgtatcctgc cgtattcagg
    22801 tgatcgcgga acgaggcaaa ttgcgaaggt tatgaaaagg aagatcaaac aacgatttaa
    22861 tcgacttgaa aagagcgtcc aacagctcgt tcaagatatt caggctctta aattctcgtt
    22921 cagcaccatt gaagctgaga aaaggatcta cgcttccgag aaagccacgc gggcaaataa
    22981 agtggcaaca acaagacggg gggcatctcc aagagccatg aagataaaag agccagtagc
    23041 gacgaaaagg gccgcttcca aatcaccctc gaaccttttg gcaagttagt cgaagatagc
    23101 ccaatctccc taagaggacg taacattcgg actgttgctc aactctccga aggagccaat
    23161 ggtaattggc acatacatgc ctccggcata tatggaacat tgactaatca agaattgttg
    23221 atatagcatg gagacatgcg cacgaagacc aaacagttga ccgacgtggc cacggtattt
    23281 cacgccttat cggatgaaac tcggctgctg atcctcgaac aactaaaggg cggcgagcag
    23341 tgtgtgtgtg atctgacaga gatttttaag acgggacagt cacgactttc ttttcatctg
    23401 cgagtgctga aggaggcagg gttaatcctg gcccgtcctg aaggtcgatg ggtgtattac
    23461 tccctcaatt ccgatgcagt tgaagagttg caggatgtgg tgaattcgct caaagcggtg
    23521 tcatcccgcg ccgcgaggca gggctgttgc ccgtgacatt tttttgccct catacatcaa
    23581 caattattga ttttgcggga tgaaacttat ggatgccgcc ggagtcatcg ctcaacaaac
    23641 tcttcctaca gagaagagac tcaatgtgtt cgaacgttat ctcactgtct gggtggcctt
    23701 ttgtatggtg gcaggtatgt tgctgggaac gtccgctccc ggcctgatcc agatgttgcg
    23761 agggatggag ttcggccagg atagccacgt gaatttcccc atggccgtcc tgatctggct
    23821 gatgatcacc ccgatgatga tgaacgtaga ttttcgcgct gtggcgaaag ttggtcagcg
    23881 ccctcagggc ctattggtta ccctatttgt caattgggtc gtgaaaccat tctctatggc
    23941 cctcttcgcc tggatctttt ttcgtttcct gttctccgcc tggatgagtc ctgctgaagc
    24001 cgatcaatat attgctggcg ccatcattct tgctgccgcg ccatgcacag ccatggtctt
    24061 tgtgtggagc tatctgacgg atggtgatcc tgcctatacc ctggtccagg tgtcggtgaa
    24121 tgatttgatt atgttggtgt tgttcgctcc aatcgttggc ctgctcgtca gtggagcctc
    24181 ttcgcttact gtgccgttgg cagttcttgt ctattcagtc atcgggttta ttgtgattcc
    24241 cttggtattg ggagtcgtga tccgacactg gttcatcagt cagcgaggaa agacgtggtt
    24301 cgaggagacg ctcctgccga gctttgcgcc catgaccatt ggcgcgctgc tcgtgacctt
    24361 agttctcatc ttcgcctttc aagcggacaa tattctcgcc aagccactgc atgtcttgct
    24421 gattgcgatc ccgattctgc tgcaagtgta cttcaatgcg tctttggcct acgggttgat
    24481 gaagtgggtg aaagtcccgt atgccgtcgc cgccccggga gcgttaatcg gtgcgagtaa
    24541 cttctttgag ctcgctgtgg ccacggccat tgcgttattc ggcccagaat cgggagcagc
    24601 cttggcaacc gtcgtgggcg tcctggtcga agtccctgtc atgctgtcag tgtgtcatgt
    24661 gtgtaaccgt acccggcatt ggtttccttc gaaggaggcc acagcatgat gcgtatcagt
    24721 gacggaacat ctccaggtgc tgttcgaatt gtcctgtctg cactcgaatc acatgctgaa
    24781 agacgaccaa cacatcttca tgactcggac tctgatcagg caaaccggac tgctaaatgt
    24841 agggccacag aaagtgggga cctacatgga taggcttggt ctgtttggga tcctggccgc
    24901 caccatattg ataggtgtgt attgcttcga aaaagcgttg aagccgttgt ggccaggact
    24961 aagccaggcc cccaaccttc acccacattc tccaagagtg gttgctctat atggctctgt
    25021 tcataggtct cctaccccta ttgtacggaa tgctgaggct cgcatgctca gtgagttgtt
    25081 cgcagggcca attacaaact gaattgccaa gagggaggct gcatcatgaa acgatttcat
    25141 ctccacatgg gcgtagagga tctcgacacg tccattcgct tctacacggc attgttcggg
    25201 gttccccccg tcaaaactaa atcagattac gccaaatgga tgctagatga cccgcgtatc
    25261 aatttcgcga tctccacgcg agccaagaaa ggtgtcgacc atctgggcat tcaggccgat
    25321 ggcgaggacg aactcgcagc gctacgtggc cggattcagg ccggccactt gccggtcgtg
    25381 aatgaaggga aaacggtgtg ctgctatgcg ctgtctgata aatcgtggat ccaggatccg
    25441 tccggcctac cgtgggaaac gtatcgaacg atggaggatg ctcaactgtt ttcaggttcc
    25501 accgattcgt cggaaggcgc ctgttgcacg cctctgacca tggccccgac gaactgttgt
    25561 gaaccatctg aaaaaacggc ggggtgttgc gactaatgga aagcgcaatt gtcacagtat
    25621 tggtgctgtg cacgggcaac tcctgccgtt ctatcatggc ggaagccttg atcaatgctc
    25681 tccgccccgg gcgctaccat gccgtaagcg caggcagcca tcccacagga tatgtgcacc
    25741 cgaaatccat cgacaccctg aagcggcatg ggattgaccc gggtcagccg aaaagcaaat
    25801 cgtggaatga gttttctcat caaacgttcg atctcgtgat tacagtgtgt gatcaggcgg
    25861 cggccgaagc gtgcccgtta tttctcggag caccgaccaa aatgcattgg agtacaccgg
    25921 atcctgcgaa ggcgactgga tcagaggtcg agattgatgc ggcgttcgac caggcgtttc
    25981 tgatgttaaa gaagcgtgtc gaacatttaa cctccacaac ttgagccatg gcgattcctg
    26041 acaagacctt cccactcagt gagcggtctg gcaggaatgt ctgcatgaac agttggtatg
    26101 ggcaatcgtg gagagtctgg cggctgagag cgaatcggag aggaggcgga tttgaagtga
    26161 atccgcgcat tcctatccgt caatgtcgcc gatacgcttg aaggcgtcga gcaagcagcc
    26221 taaagaacgt gactctgccc tggcagggag cgcggttgcg tttcatccca tagaggcctc
    26281 aatgcaccac ccattcattg agaccttgaa tctcgagtgt gcgaattcgc gacgagcgct
    26341 gattttggaa gatgagtgac gagtcttgtc actggtgccg ttgtgtatcg actccacttc
    26401 gtttgccgga gcgtcactgg ttcacgtgta cgaccttggc cggcgggaaa ccgttgaagt
    26461 aggtgctgct ggcgccgcaa taggccccca tattctcggc atacaccaat tcgccgcgat
    26521 ccatgtcggg gagctgctcg accaaactaa tggtatcaag cgcgtcacat gttgggccga
    26581 agacggcaca gatctgcgtg ggatcttttc tgaagctttt caagtgatac tggcagtggt
    26641 cgaagatcac gccgctgtag gtatgataga ccccgtcatc gagatagtag cagagcttgc
    26701 ctccacgcac ggccttgccg atgatttgtg cgacggaggt ggcggccgaa gcgacgagga
    26761 agcgacctgg ttcggcgaga atttcaattg gctggggaaa caggcggtcc agttcggcgt
    26821 tgatggtctt tgccaagctc tgaaacgcgg gcacggagtc gtcgtaatgg gcggggaagc
    26881 ctccaccgat gtcgagtagc ttgaggtcaa atccgcgagt cttggcctcg gagaagatac
    26941 cggcagcgag gtgcagagcc tggatgtagt tttgcacatt cgtgcattgg ctgccgacgt
    27001 ggaagctcag gccctcgacc acgagtttat tattgtgcgc aaaggcgatg aggtccaccg
    27061 cctcgcccgg caaggcgcca aatttgctcg ataactctac catcgagccc gtattgggca
    27121 cactcaaacg cagcacgagg cctgaatgcg gagcgtagcg ggcgatcttg agcacctctt
    27181 cgtgattgtc ataggtgatc aatggcttgt actggtctaa ttgcgtgagc gtttcgatgg
    27241 ccttgatggg attggcatag atgatacgat cccagatgaa atcctggcgc tgctgagccg
    27301 gcaggtgttt gatcttttcg tgcacgatca agaactcagc catgctcgcg acgtcaaagc
    27361 tggctcccac gtcataaaac gtctgcacga tggccggatc gctgttcgct ttcaccgcat
    27421 agtagacttg tacgcgtggc aaatgtttgc ggaactggtc atagttctct cgcagcacgg
    27481 catgatccac tacgaccaat ggcgtgccat gcaggtttgc caggtcaagt aaggtttttt
    27541 gatccatgat ccctcttcat ttccgatgtg tcgcgacacc cccaccgtat ctgccgttga
    27601 tgactcaaag tcgcatggcc gggcttaatc cccttccatg atcagaaaat tcttaaactg
    27661 ccacgggtcg gacctgtcga gctggggctg attgtagccc ctaaaaaagt tggaatagtg
    27721 cttcagtgga ttccagtccg aggcagcgga gatgaatttc cccaaatagg gcttgctcat
    27781 attgaggata tagtcgtgcg ggaggttgtc gggaacgcac aagcccctcg aaggattctc
    27841 aagcatccac atacaggcgg cgacgacgga aatagcgacc tgcatggtgg tcgcattctg
    27901 atgcggcacc aagcgacggg cctcttcaat gtctagatgg gagccgcacc accacgactg
    27961 gtacgggtgc cccatcacga gtacccccag gatgtcggcc ccgctgatga tctcgtcggt
    28021 catgatacgg gttcgcgatt gcagtctgta gtcggagccg cggagttcat ggagagacgc
    28081 gatggcggca tcgcaggggc aataggcgta gtgcaccgtt ggccggtaaa tggccttgtc
    28141 gccttcccac acggtgagct tctcggtaat gctgaacgcc tcgccgtggc ggacgaccat
    28201 gccgataatg ttgtggtctg gcggcaccca acttgcgacg aaggtgttca tgcccatcct
    28261 cgccaggcag atttggcttt tggggccgtc ggggtgctcg taggcgaagc gaggtaactg
    28321 tttttcgtgg gttccccagc ccatttcggc cgtggtcgtg ccttcctctc gaaaaccttc
    28381 gacgctccag gtgttgacga actcgtcgac ctgcttcggc cgatcagtga tttgcgtatc
    28441 gcgctcactg caatgaatga ctcggacccc gagctggtgg gcgagatggt taaactcctg
    28501 cgcctgggca tgatgcgcga ttctctctgc ctgctcccca ctgaatttct tatctgccag
    28561 ggtctgccgg gctatgtcca gaagcgcatg cttggtgaag tgactaatca gtccggggtt
    28621 tgccccatgt tcgacgaccg ccgtgggccc aggctcgccc caactggcca tcatgcgacg
    28681 gagattcata tggcgccagt acaatgtccg ctcagtagga tgtttgtcgt ctactccgca
    28741 atacggatcc caaatctcta ctgatgtgtt gatgtacagc acacctctgt cgtgacacca
    28801 ctgtacgatt tcgcagcaat cgatattcca agccaagtcg atgagaaggt cccctcgaga
    28861 cgcgtgtttg cctagtagcg tgcccagatt ctctggcgtc acgcgatctt tgacaaacgt
    28921 cacaccttgt ttgatccaag gggccaacgc tgcctcattg ggatcaaagt ccaagatagt
    28981 aatgcgtttc ggatcgacgc ctatgtgttt cagcaaaatg ggcaatgtgc atcgcgcgac
    29041 agccccaaac ccgacgaaca aaatgcgatt tggaaatacc tgcatctaaa gcctcccact
    29101 tacacaaccc gtaggtctcg aaccctccgc ccggtggcca acaatactcg gctgggatga
    29161 tcgtgccacc cgtattcagg aggggtggta ttgtagtgca ctgaagggca tttgtgctct
    29221 gtctggtgtt aagaaacgga aaattttatt ctctttgtat tgcgagtctt catcacatgc
    29281 catcgatatt tcagggcccg ggagatcgga tcggcagcga gaccgggagg cagggaggat
    29341 gtgacgaggc tcgcgaaacg aggaaaagtg tgggggcgta tttgaacact aggagcggaa
    29401 gggaaaggaa cttgtcgcgt gcgccggatg cgattatctc caggatcaca gtgcaaatgg
    29461 tcgaaggcga gcatttcagc cgagccgctg ttgtattacc tatgttcgtt tgaacattcg
    29521 ttgtggggtt ctgaagtgct atagagccag agttcgaggc tccttcggga acatgcaagt
    29581 tcgtatagat tgccctcaag gtgatcgggg cttgaaatag cgtcaacgct atggagagtt
    29641 tgcgggatga agtggtgatc ctagattgcc ttggaaccag cgccacagcc ggcaggtctt
    29701 gaagaaggtg tgaattacct gagtgcttga aaaaatggtg ggccgtgtag gggtcgaacc
    29761 tacggcccgc tgattaagag
//
LOCUS       DAOQPD010000048        29555 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_703_length_29555_cov_15.131390, whole genome shotgun sequence.
ACCESSION   DAOQPD010000048 DAOQPD010000000
VERSION     DAOQPD010000048.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 29555)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 29555)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29555
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_703_length_29555_cov_15.131390"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            571..1704
                     /locus_tag="PK063_11875"
     CDS             571..1704
                     /locus_tag="PK063_11875"
                     /inference="COORDINATES: protein motif:HMM:NF012798.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HMZ97797.1"
                     /translation="MGLTKRKDSYYVAFSVIVSDDGKTFKLAPGVPGARLKRWKVGCL
                     NKTIAKEMEATIRINLLQGKILTEESRPVLFSEWAEQYLDLEEVRRLRSFSTRAIHVS
                     HLLKFFRDKPLSAFTCEDVRKYRSWRAGQGVSVQTINHDHMTLTRMLNLAMSDQFNLI
                     SRNVSASVPKPDPKNERDRIVTPEEWAAIRAHAAPHLARFLTVAYDLGPRRGELLKLE
                     WSDVDMKRREFTLRETKNGEARTVPMTPEVYEAFRQCLKERRLDTSRVFLYKGRPIQR
                     RLTTAFKAACRRAGIVYGRKNGGITAHDFRHSAATSLRRAGVDTMTAMKIIGHKSEKM
                     HRRYNQISPADLQRAVDKLVIYQADQASGADTVLTHEKLHHEA"
     gene            1734..1808
                     /locus_tag="PK063_11880"
     tRNA            1734..1808
                     /locus_tag="PK063_11880"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1766..1768,aa:Gly,seq:ccc)
     gene            complement(2104..2823)
                     /locus_tag="PK063_11885"
     CDS             complement(2104..2823)
                     /locus_tag="PK063_11885"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ97798.1"
                     /translation="MSRKEEEEEEERATTVVAIVSNNYLLRLGLQRIVEQEKWLRLIG
                     QTANVTTFDDVIARERPQIMIIDTEIESDVPGLIQKIKATAPETKTILLTGMDQAECT
                     RQAFACGVDGLVPKIQPSPVLIATIDYLARAAAAPVTFTGSNTAPLNKPHRPTIHTAI
                     ATNPAQSKWPDGLTEREQEVVRLVSEGLSNKDIANRLCISSITVRHHLTSIFDKLGVS
                     NRQKLLLRAHQNGLTRPPALA"
     gene            3899..5632
                     /locus_tag="PK063_11890"
     CDS             3899..5632
                     /locus_tag="PK063_11890"
                     /inference="COORDINATES: protein motif:HMM:NF014453.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HMZ97799.1"
                     /translation="MKAVIMDGAPWAGTMLAFPVGNELLIDHLLSAVKRLGIREVAVV
                     SCDQDSYVRDLVCRAGHSYGLTVLWRTEQVYRGTAGSLQAVEDFLDTPTFLGIHANVY
                     LRDVDLAAAFKAHDEHRADITLVTQRMAGTDDDLESVEVDPAGLVSRVNILHWSRNRR
                     SQLTPCGLYVFSREVLSQIPRDEYFDVNEQLVPLMRNRGGVIRAHQIEGGVHTIVGPD
                     DFLWLNREILHKDIQGSGHGNGRLGGVEDIVIGENSEISPHSFLLGPLVIGPNCVVED
                     YVHLIGPAVIGPTSYLEKGSLVRESVLRSGTRVQGNARVEYSVIAGDETVPEGMRLRS
                     AFWSTAKPALYEPHGVPAQVSSNRMLQRSRYSQRPARRMQGGTGQRSIYGMVKSVVDV
                     TGAAVGLLFAGPLMLLIACAVKLDSPGPVFFSQKRCGKNGKEFWMHKFRTMVPDAEQR
                     QKDLKAQNSVDGPMFKLQEDPRITRMGKLLRKTSLDELPQLLNVLRGEMSLVGPRPLA
                     YDEMKFCPTWRDARLSVAPGLTGLWQVKARNRNRFSEWIRYDLEYVRTHSLSLDLYIL
                     IRTARVLLKGV"
     gene            5632..7866
                     /locus_tag="PK063_11895"
     CDS             5632..7866
                     /locus_tag="PK063_11895"
                     /inference="COORDINATES: protein motif:HMM:NF025179.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNVR domain-containing protein"
                     /protein_id="HMZ97800.1"
                     /translation="MNVPYTTGLPDVDSTQTVGRSSFGVREHLITIFRQKRKLLTILG
                     MATLVAGPGSFLMTNIYSAEVRLLIQNARTPFSMSTPLTGQVFTPSDITQKDDVATEV
                     QIFTSPILLDKLVDYFGNERVLAAMRGRWDWVGEIPKTVFKQLSGLPPVAKLLTTIGY
                     VPKPEDLHYQAVQKIRAHLNVEGVRQTHVFVASLDSPDPEFSADALNALVGIYMDHQL
                     SVRKGKGAREFFDEQTKQMRGELQQAELRLQAFKDKWNIVSIEDQKRHLLQQVTHTEA
                     ALRESQVQVAETEVRISKLKERLAGQQEAIPLTNVSERNPMLDQLKNRLMQMELEYSQ
                     YVPDSPAAAELVREIAAVRARLQAESSKVTGAATSGLNQNYQELKRTLVMEEGRRESL
                     RPRLSELTKQFKSYRDSLNTLDQREMELQGLMREVKVKQEAFDIYLKKEEESRINEVL
                     DRKGISNVNAIEHATAPQKPVQPRKFLNLVIGLLIGLVGGFGSAYVSEYMRRTFVTRE
                     EAEDNLGRPVLAALPLVRPDTSDAGSFDLELRQAAQHVIRSYHERGLRTLLVTSALRG
                     EGRSHVAGALARVLAEQKFRVLLITFEEAGAEKLNTGDAAAGAKQATDTGRFRQDIPE
                     ATDRIHLHRLLVRHREGTALEFAEHLAEVAKTMRDRFDLIVIDGPALTSFPEMRVAIA
                     GIDGTILVVEAERTVSVAAARTTTAIEAAGGHLLGLVLNKRRYIIPEWIYGRWLAAGG
                     REGV"
     gene            7863..8657
                     /locus_tag="PK063_11900"
     CDS             7863..8657
                     /locus_tag="PK063_11900"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013382.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HMZ97801.1"
                     /translation="MSESIAGVMQVDEKIVPAEGFVREDGWYAPYDYWLTLWGLYDLY
                     AYALALLGDVKGKVLLDCGCGPGHTSVMLAKRGAIVTAFDTADGQLDTARRLAQANGV
                     NVTFLCKPFEELDFPDESFDVVFGTFVLHHVDLPKASQQLARVLKPGGKAVFIENSAL
                     NPLLMAARSKVCGRLGVPQYSDDHEHPLTRRDIATLQSAFPGACTIHFPSFLFFRLLD
                     FYVFKKRWSWMTALLRHCDQLAGSIPIVRRYGYLQIVELGKGQGRA"
     gene            8650..9924
                     /locus_tag="PK063_11905"
     CDS             8650..9924
                     /locus_tag="PK063_11905"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HMZ97802.1"
                     /translation="MRSKPSKFGRGFCCALLLLSGLFLVATDARSAPATEAVAGCRTE
                     APALKHHRASAVDRVTLTSPSNGVYIGLYSIGTIPEDRLRFTAKSGHRPAIVFTFHDW
                     VSDDDWTASSPHFRTFTDPLESSRLSPLQLAEQVRSEGGVLAVAWAIQCCDWESHLFW
                     YGFRKPTVTVDRLLRGDFDSYITSVARQIKAYRHPIMLTLFSEFNYQGMMGFGKEGRT
                     RLDDVDHVCRLYGDPTWPDGPERIRDAFIYVIDRFRNEDVRNVTWFMYAGSHYMNPQH
                     EDYSPWLHPQYFYPGDDYIDWVGQSAYFIDTRSVPKLRQQELATSFAGALGPGYAAWG
                     AVTDRPLFLPEFGVLGDKTSSRARVIEEVFRDVLPQFPRVRAITLADFKIAEDYYEVP
                     RFGTFEDETEAWKRAVRQNPRYLKQASFKGGE"
     gene            9932..11308
                     /locus_tag="PK063_11910"
     CDS             9932..11308
                     /locus_tag="PK063_11910"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024629.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 39 protein"
                     /protein_id="HMZ97803.1"
                     /translation="MALKRSSQWLCLCAIFAVCFTLRIGVGGVIDATVSVVKRADVYS
                     DIAVNLARGHGFVVVAGGEPIIWRAPLYPAFLAQVYALFGEYSETGVFLAQSALDSFT
                     AVLIFYMGTRLFSETVGLLSAVSFALHPLSAYYSLRFLSEPLFTLAFTALISAWIAAT
                     TTRRLMAYTVVGALIAVAALVKPVALGLWPLLATCAVWQLRDEPVRALSAVTGLTLAC
                     LMVLAPWALRNYRATGEVVAVATGGGYALWLGNQMVSEGKEDWEVDEVTRAHLFERRG
                     TVITGAQPSDHALAGYPSIRSATQPVHISVPEDHAFFIAAWREMSSHPFDTALLTVRK
                     FFRFWFRIFLPDNRWAQSYIVVFQTLFLSVAVLGMLEAKRQGITVFALILPVLFLAAV
                     HAMTFSTIRYSIPTIPVLSILQAAGLRAIVHALNERWGLSLGVSWVRWLKAALVGSAA
                     RSYRGTAL"
     gene            11355..12584
                     /locus_tag="PK063_11915"
     CDS             11355..12584
                     /locus_tag="PK063_11915"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HMZ97804.1"
                     /translation="MKPIRVVIIRNCRGITGMTGGETYLLSLLKGFDPQKVRCLLVCI
                     VNPALGETSWLRELKQTGFEHVTIPIGNPFNLSDVYKVSSLIRSYEADVVHALDHRSD
                     LIGILSARLTGRPVLASFLGWVNFPKGSWRATVYPWIDRMILKRLDAVITDSVAIGTE
                     LKMREQDPPVVAIRNGIDTRWFDPTRTLTPFSQESFLKGGHFVFGMVGRIHPVKGHLN
                     FLKAARTLLETHADCRFLIVGTVLPGFEHYRQGLQDFIREQGLEQSVLITHVSLAEIP
                     AVFAGIDVLVAPSFAESFSFTLLEGMAMEKAVVSSEVGGAGEMITHGETGYLIPVDDV
                     SRLTETMRMLRAAPEKVREVGLRARKKIVNDLGIEAMAARTHQVYRSLIEFKGKTSGG
                     AGDQGRLREQLAMISAK"
     gene            12621..13577
                     /locus_tag="PK063_11920"
     CDS             12621..13577
                     /locus_tag="PK063_11920"
                     /inference="COORDINATES: protein motif:HMM:NF027681.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HMZ97805.1"
                     /translation="MKILITGSQGFLGKSLAHYAVRNGHHVLGVSRSDADGLIAGMES
                     IRCGLDQAGFVDVLNGFAPDVVVHAAGSASVGYSFQQPREDFLMAVETWASVLDAVRK
                     AEGNPLVIFPSSASVYGNPTRLPVPEGAGLRPISPYGFHKVICEQLAQEYAHCFGLNV
                     VSARLFSTIGPFQQRLLVWELFRQAIDANPYLTIQGTGTETRDFLHIDDICRYFLGIA
                     EREPKGFWAVNVASGESTSVRTMAEMVTRLVGSTQAIVTLNKDLPGDPKQWQADTTLL
                     QELVPYQAPDIANGLEDCVRHWLSEPSLSAQRELRCSVEGHS"
     gene            13704..14990
                     /locus_tag="PK063_11925"
     CDS             13704..14990
                     /locus_tag="PK063_11925"
                     /inference="COORDINATES: protein motif:HMM:NF024832.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HMZ97806.1"
                     /translation="MKALSQQTAVVFAGKMTGACLGFVMSLLVARWMGPEEFGLFSLF
                     IVILIFGNDVLGDGLSPGVVRFYSMYRRADPSKAAEVLTNALALRMLLGIPVVVVGVA
                     VGSQYAARVFHSQLYVLPVVLGLVGSFGAALWSFNLSVWQAREEFGTYGVMVALINVL
                     RVLSLPLLFLGGYLTLGGIMGSHVLVYFLCALSGTWALRRHLAHVRVNGELLRELFRF
                     SKWPAMASLCFILQVNLGVPVLNYFVNAREAGLYGAGSSLLMGVDFLTVSLLTTLLPK
                     VSQLTGIEQCRSYVQRSFPMYALIAAAILPLLFFARPVVIGLFGSAYEGTIEVFQVLF
                     VGTLGTLVTHPLYLVLYTMNRPHLHTLSGIVGLIVWLLAGFWLIPQFGAVGAAWTTLC
                     SRLVQSLMIVVILWHALGLGGSSGLARSVMPDVRGS"
     gene            14987..16483
                     /locus_tag="PK063_11930"
     CDS             14987..16483
                     /locus_tag="PK063_11930"
                     /inference="COORDINATES: protein motif:HMM:NF016800.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HMZ97807.1"
                     /translation="MKPSDQTYTIPTLLGATLGASVLALSTKALAIVIACSAFLSMTA
                     SAVFPYYILVATIPVQVDLLGGLTVTKLITPLAIGMVTINALIHRGPWPVLLRWPAGY
                     LAGAFFLASLLSLVLAEGLRGLPGEAAKIPVYGALFFFTLTFNRHPEDMRRLLWVITI
                     TGVGEALITAAQVHYGFVMPGDWRRNVGLPSEGGVDGAFMSISEGKVRAEGTTAHPIF
                     LASFFLMSMPCTAFLLFQEKHPWVKAALGAMLSLMAYAWFYTFARSSVIGFALLILVG
                     LWLQFKFVRKLSLIVLVLVLAGGLSYQVVSEWFQVGVQTVENQNLFGKADLNEGSGSF
                     AFRRESIVGGWNLFLAHPWFGVGFGQAINHYVKYLPAWADHYYHPAVIHNMFLEVASE
                     LGVFSLSAFIGLWVVAFVSLKRGLRIPDVRPYAVLLSSILAGQMIFLMITPMVREIWL
                     TLPMAIAIGHMAKTHTRATFGIPFRQVGARAQLRRIVDRGNGLPAGLR"
     gene            16491..17495
                     /locus_tag="PK063_11935"
     CDS             16491..17495
                     /locus_tag="PK063_11935"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF025025.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HMZ97808.1"
                     /translation="MKIRVSVVIPAYNATKTIGDGLESFARQSFPAAEVEIIIVDDGS
                     TDGTPEYLETYARSWGLAQPRLRVMRQAHQGPAAARNLGAAAAQGDFLLFTDADCVPH
                     VDWIKEMVAPFALSAIAAVKGAYKTKQRSLVARFAQAEFEARYRQLAATEYVDVVFSY
                     SAGFRREVFRSIGGFDTSFPVADNEDTDLSYRVATAGYKIKFNPAAIIYHQHPATLKQ
                     YLRKKHSRAYWRVMVYKRFPGKAIRDSYTPQTLKLQIGSIVLAAGAIAFVPFVPHAMY
                     VAALAGGLFTATALPFLWQLPREDPGLRLVAPFLLVCRAAVMASGLMRTVPLLMSKTN
                     "
     gene            17525..18127
                     /locus_tag="PK063_11940"
     CDS             17525..18127
                     /locus_tag="PK063_11940"
                     /inference="COORDINATES: protein motif:HMM:NF014606.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015159 - polysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015774 - polysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis/export family
                     protein"
                     /protein_id="HMZ97809.1"
                     /translation="MRRILHTSWAVCFMVLCLVTTVQASETEAVLTPSVDAGWSGPFR
                     IGAGDVLNVFIWKHKELSTIVTVRPDGKINYPLIGEIEAKGLTLGEIEERINKQLKQH
                     IQDPQVTVILEATHSFRIFVLGEVMQPGVFDLKGPVTVIQALAMARGLTTFASRNKIF
                     IVNPARGNDQRIPFSYSKFVQGEDTNQNVMLRPGDTVIVP"
     gene            18320..19522
                     /locus_tag="PK063_11945"
     CDS             18320..19522
                     /locus_tag="PK063_11945"
                     /inference="COORDINATES: protein motif:HMM:NF021589.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HMZ97810.1"
                     /translation="MTSPMLFAQESDNSEFVRPQREFGELPSWQNQVSYDRMPASEKL
                     LLGAPIRRDGFTPRLTVTEEYTDNVFFTAKNRGTDYITKIAPGLGYRTSGRDGQLSAD
                     YSVESRVYANNSNQNRTVSRQNGELFGLWNLSDRTSLTLFDRFESFQDPTEQQVPGIL
                     GAFGRTSINIGALMMRHRLTPSVDLLANYGNFLWSVDAPGAINSMTHEGEVGARVRET
                     QWGRTTVKYRFRFFDFQQGRDFQSHSALVAQEIDLSETLVVSGTIGAVRVEPNPSTVE
                     VLAQASIKKSIGDALYELSYMRDVFPPSGGLSQPLVGDFVRATAKIRLANNFLFDAGL
                     TWILTSTNSDDLTVHTLKWNVGISYTPASWLVARLGYDMFDQREDILGTSASRLANKV
                     SLRMIATF"
     gene            19594..20745
                     /locus_tag="PK063_11950"
     CDS             19594..20745
                     /locus_tag="PK063_11950"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HMZ97811.1"
                     /translation="MEPVSDGLRILFIAPAPRAGTVQYTHNLANALVDRGHRVTLVTG
                     VGFELADYPRKYTALEVFDRYRPRPLRLCRFVWHCLTFRPQIIHLQGAQHPALYILLW
                     AMLRLLGSASFVYTPQDVLPNSLRSYHIRAFRFLYARMRHVFLNAKQNEPLVIEHFAV
                     PRDRITVLPIADLTAFVREHVAGESPDIPAASRVVLCFGLIEPRKGIHTLLSAAPEVL
                     RQVPDALLLIVGKPLMDIAPLQRQLADLGLQGRVRLVPQYVSFAQMAGYFTAARLLVL
                     PYENGWNSGVLASAFGFGKPVIATRVGGFDEVVSDESTGLLVPPKDPAVLAQAIVRLL
                     RDDALYARMVVNVRQAAAEISWETIARMTEARYGDVVGIGADCAVSQAR"
     gene            20723..21589
                     /locus_tag="PK063_11955"
     CDS             20723..21589
                     /locus_tag="PK063_11955"
                     /inference="COORDINATES: protein motif:HMM:NF012472.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HMZ97812.1"
                     /translation="MQYRKLGNTGLTPSVLGFGCSMIASLATRYSPSEVEASLREARE
                     AGITFFDTADVYGQGDSERLLGKLFRRGGEGMILCTKAGLTVGSMEPVVRVVKPVMNS
                     ILRRWRTARVATTQARRRQEQQCFDPDYLSGRIEGSLRRLSVDRIDLFLLHNPPVDLP
                     QREGVFELLTRFKAQGKLRWFGVSCRSLDDAYEWLGQPDVACVQIPVDRSRIEAAIPV
                     LERARAQQVGVIAREVFAQDALAKGSVSDALGPLVERAEIGVVLAGMSCRRHVQENVR
                     ALDVAMRCSHVA"
     gene            21579..23237
                     /locus_tag="PK063_11960"
     CDS             21579..23237
                     /locus_tag="PK063_11960"
                     /inference="COORDINATES: protein motif:HMM:NF017050.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMC family oxidoreductase"
                     /protein_id="HMZ97813.1"
                     /translation="MLLDARSISNGAILTADVCIIGAGAAGITLAMELLATGLNIILL
                     EAGGKSKAGESQSLYQGELNDPVRHLPLDQARYRQLGGTTSLWGGRCIPFDSLDFDQR
                     EWISHSGWPFPQKEFDGYYRRAHSYCECGEYDYRVSTALPGAPPSMLPGFEDGDVNTS
                     GIERWSPPTQFGKVYRPVLTRADNLRVLLHALAVELQTSSDGKRIDSVDVATFSGPRF
                     TVRARTTVLAGGGLETTRLLLASRGVHREGIGNHSDWLGRGYMSHIHGVIASVTLTAG
                     QDVMFGYEADPQGVFCRRRIAFSEEAQRRHRLLNLYMLLDRPLVGDPGHGNAVLSAAF
                     LLKRLLGGRQQEELGKGKYSLYWRHIKNILAGSPQALSVLPKFGRKRLLQRRRIPSLL
                     MRSRSNTYYLYFQSEQVPHWENRVTLDAARDEFGTPRLRLHFEVMEQDRQSVQRAHEL
                     IDQELRRQNCGYVTYLGNDVSQLMRDVKAVLGHHIGTTRMSADPSQGVVDAQCRVHGV
                     ANLFVASSSVFPTSSHANPTLTIVAMALRLADHLKALHSGVTRV"
     gene            23268..24278
                     /locus_tag="PK063_11965"
     CDS             23268..24278
                     /locus_tag="PK063_11965"
                     /inference="COORDINATES: protein motif:HMM:NF027681.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HMZ97814.1"
                     /translation="MYWKNKRVLVTGGAGQIGSHLVARLAAAGAQVTVADNLWRGKKS
                     NLLGDDGAPVIDMESRFLELDLCDYRNCERATEGQDIVYHLADVVAGINYVFGNQFSL
                     FNTNLIIDSNMLRAAIANKVSSYVYVGTACSYPAERQSKLNPPPFKEDDVYPASPESS
                     YGWSKLMGEMGCDLARKEKLLDIGILRFHNVYGPHCEMSPEKSQVIPSLIRKAVRHPD
                     EEFVVWGSGKQRRAFVFVSDIVDALVSVATKGLNQGVIQIGPDYSTSIKEIAELVCAI
                     SGKPIDIRFDTSKPEGDVDRAADWTRARDILGWSPKTSIQEGLERTYAWCDRQVFQGV
                     GR"
     gene            24384..25391
                     /gene="gmd"
                     /locus_tag="PK063_11970"
     CDS             24384..25391
                     /gene="gmd"
                     /locus_tag="PK063_11970"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008446 - GDP-mannose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HMZ97815.1"
                     /translation="MKKALITGISGQDGSYLAELLLAKGYEVHGIIRRSSSFNTGRID
                     AIYQDPHVAEPRLRLVYGDLNDASSLNKILRTIQPDEIYNLGAQSHVRVSFDVPEYTA
                     EVTALGTVRLLEAIRESGIQPKFYQASSSEMFGKVQEIPQRESTPFYPRSPYGAAKVY
                     AHWITVNYREAYNLFACSGILFNHESPRRGETFVTRKITRAAARIKLGVQQELYLGNL
                     DAKRDWGFAGDYVQAMWMMLQADQPDDYVIATGETHTVREFLDRTFSYLDLDWKQYVK
                     IDPRYYRPTEVDLLIGDATKAKKVLGWEPKVSFEDLITMMVEGDLRAERSILDGTRGA
                     R"
     gene            25394..26353
                     /locus_tag="PK063_11975"
     CDS             25394..26353
                     /locus_tag="PK063_11975"
                     /inference="COORDINATES: protein motif:HMM:NF027681.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthase"
                     /protein_id="HMZ97816.1"
                     /translation="MSFWKDKRVVVTGGAGFLGTVVVDQLRKLGCRNIVVPRSHDYDL
                     VDMGDVKRLYVDAAPDLVLHLAARVGGIGANQTHAGQFFYDNLMMGTQLIEVGRQQGL
                     KKFVAVGTICSYPKYTPVPFREEDLWSGYPEETNAPYGLAKKMMLVQAQAYRQQYGFN
                     AVVLFPVNLYGPGDNFDMQTSHVIPALIRKCVEAKERGDDRVVLWGDGSPSREFLYVT
                     DAARAILLAAEHYNGNEPVNLGTGQEITIQALAHVIADAVGFTGEIVWDTTKPNGQPR
                     RCLEVSRAKQLFGFEASTAFVDGIQQTVAWFYANRGSIREVVF"
     gene            complement(26373..27764)
                     /locus_tag="PK063_11980"
     CDS             complement(26373..27764)
                     /locus_tag="PK063_11980"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97817.1"
                     /translation="MKIHYAAVLALSFIAGIWISFDASTAEAQSRFSRKRQVQTQSVT
                     PPTTQTTAARDYSILKIVPPPAGGLYMGQYEWVQNDIASFESASGRKTALWSKYRGSW
                     GNGYDAAGQPHLDVQAANLAWQEGKVIVVQAYNTHPAPGESEAPQGFTVDKLLNGVYD
                     AELRRFAAELRQYGKPVFFIAGREPNGIGADYFGGFGPAGDQSLRWAIENKRGFSEFN
                     PSSLPYASLYSDIGTPQVCDGTERLKAAQRYYYDFFVRREGLKFLTFDTMGWSVNQVN
                     QIEYDVNELPSTIDKAYARQLLESCHAFSNFYAGDQYIDWISLNFYMIDYYAKDWPGM
                     TQDYVIPIENHFAALDKVMQEVKTVAPTKPVFFMELGFPDGMSQNSSWAAQKIATGIP
                     RIISGYPQIHGFAMWSAHPSWLIPGVFPYDCLIRPGTQQGTALKNVVTTTPSAFLSCV
                     YLSDGKLHPNCMN"
     gene            complement(27971..28339)
                     /locus_tag="PK063_11985"
     CDS             complement(27971..28339)
                     /locus_tag="PK063_11985"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97818.1"
                     /translation="MMTRSWTFGLMAILIGITACSHFQNREAAYLDSVKGRATQTEVR
                     QELGAPKAVRKSDEGETVWVYEIREQQAGNRYTAPGIWCEEYLLTFDGAAVLQKWKQV
                     SHFHGGELMPTECIPGMEKP"
     gene            complement(28605..28796)
                     /gene="rpmB"
                     /locus_tag="PK063_11990"
     CDS             complement(28605..28796)
                     /gene="rpmB"
                     /locus_tag="PK063_11990"
                     /inference="COORDINATES: protein motif:HMM:NF013026.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HMZ97819.1"
                     /translation="MAFACDLCGKKHQTGNNVSHANNKTKRVFNPNLQRVKALVNGSA
                     LRIRVCTRCLRSGLVKKAV"
     gene            28957..29214
                     /locus_tag="PK063_11995"
     CDS             28957..29214
                     /locus_tag="PK063_11995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET transporter"
                     /protein_id="HMZ97820.1"
                     /translation="MDKVTFIGLLAGTLTTIAFIPQLQQTWRTRSAQDVSLGMLLTFI
                     IGVFLWLVYGLLLGALPIILANLVTLVLTLAILVLKLRYRA"
     regulatory      29262..29449
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
BASE COUNT         6131 a         7395 c         8907 g         7122 t
ORIGIN      
        1 tgttctagcc ccacccttca ccaaccaagg gtggggcgta acgaaggagg cggcatgggg
       61 gctctcgcag cgggcaggcc tggagggacg gaggcgcgga aggactgtcc cactgctcct
      121 aggacccggg tcgcaccaac aagggctttt cagcagtaag cgaacatggg caatttatag
      181 agaacgggat agttggctgg caggcatctt taacaaatgc ttcttgggag ttaacatgtg
      241 caggcttttg acaatggatg aggcatcgga atatttaggc atttccaagc tgacgttgta
      301 tggatgggtc tcagcaagga agatccggtt cgttaaaatt ggacgacttg taaagttcaa
      361 gcagcaagat ttagatcatt ggatagatgg acatacggtt atggctcgat cggaatccag
      421 aaaacctgaa gtcgaccgat gtgaacggtg aagcgaagct cggacttaca aaattgaagt
      481 gagagttgtt aatgttgaat ggttcgacaa atatccgtcg aaccagtgac cctcaagcgg
      541 cgttcgtgaa gttgaaggaa aggttttagt atggggctga cgaagcgaaa agattcatac
      601 tacgtggcat tcagtgtcat tgtttccgat gacgggaaga ccttcaagtt agctccaggc
      661 gtaccggggg caagactcaa gcgatggaaa gtcggatgtc ttaataaaac tatcgcaaag
      721 gagatggagg caaccatccg gatcaacctt cttcaaggta agattcttac agaagagtcc
      781 aggccagtgc tcttcagtga atgggcggag cagtatttgg accttgagga agtgcggagg
      841 ctgcgatcgt ttagcactcg tgccattcat gtcagccacc ttttgaagtt cttccgtgat
      901 aaaccgctat cagcattcac atgtgaagat gtcaggaagt acagatcctg gagagcaggg
      961 cagggtgttt ctgttcaaac gatcaatcac gatcatatga cgttgacccg gatgctgaat
     1021 cttgcaatgt ccgatcaatt caatctgatc tcgcgtaatg tttcagcttc agttccgaag
     1081 cccgatccta agaacgagcg agatcggatc gtcactcctg aagaatgggc agctattcgt
     1141 gcgcacgcag cgccacattt ggcgaggttt ctcaccgttg cttacgattt agggcctcga
     1201 cgtggagagc tactcaaact cgaatggtca gacgttgaca tgaagaggag ggagttcacg
     1261 cttcgagaaa caaaaaatgg agaggcgaga acggttccaa tgacgccaga agtttacgag
     1321 gcgtttcgcc agtgtttaaa ggagcggaga cttgatacct cacgagtgtt tctttacaag
     1381 gggcggccaa ttcagcgccg acttaccacc gcgttcaaag ctgcatgcag aagggcgggt
     1441 attgtgtacg gccgaaaaaa cggtggaatt actgcccatg acttccggca ttctgcagcg
     1501 acttccctgc gaagagcagg tgtggacacg atgacggcaa tgaaaatcat cggtcacaag
     1561 tcagaaaaga tgcacagaag gtacaatcag atttctccag cagatcttca gcgagccgtc
     1621 gataagctag tgatctacca ggctgatcag gcatctggag ctgacacggt attgacacat
     1681 gaaaagttgc accacgaagc gtaatcatgt aatatgttga aattcatcac ggggcgggcg
     1741 tagctcagtg gtagagtcct tgcttcccaa gcaagttgtc gtgggttcaa atcccatcgc
     1801 ccgctccaaa aaaccttttc aattccttcg taacacagac cttcaaggca cgtttctttg
     1861 tcgtcatccg tggggagtcc tctgagctcg tccaggggga gcatgtttcg ctcaagggat
     1921 ctggaattga aggcgcacac tggtcatgcc cttctgttgt gtcttaccca aggcaacgaa
     1981 ctgaaggcat ctggaggtgt ttggactgct tagtctgtat ggttccttgt gcgggattgt
     2041 atgctcgggg caagccgtga atatgttcgt ttgtggaggg gggaagctgt gacggcgtgc
     2101 tctttaggcc aaggcgggcg gtctggttag tccgttctgg tgtgcacgga ggagcagttt
     2161 ctgtcgattc gagacgccaa gcttgtcaaa aatgctcgtg agatgatggc gaaccgtgat
     2221 gctcgagatg cataggcggt tagcgatgtc tttgttggac agcccctcac ttacgaggcg
     2281 cacgacttcc tgttcacgtt cagtgagtcc gtccggccac ttggactgcg ctggatttgt
     2341 agcgattgct gtatgaatag tagggcggtg aggcttattc aaaggtgccg tgttgctacc
     2401 ggtaaatgtt acaggtgctg ctgccgctcg agcaaggtag tcaatcgtgg cgatcaaaac
     2461 gggagaaggc tgaatttttg gcactaggcc atcgactccg caggcaaaag cttgtcgtgt
     2521 gcactccgct tggtccattc cggtcaagag aatagttttg gtctctggag ctgttgcttt
     2581 gatcttttga atgagccccg gaacatcgct ctcgatctcc gtatcgataa tcattatttg
     2641 gggccgctcg cgcgcaatca cgtcgtcgaa tgttgttaca ttggcggttt gcccgatgag
     2701 ccggagccac ttttcctgtt ctacaattct ttgcaagccg agccgcaaga gataattatt
     2761 gctgacaatg gccaccaccg tggtagctcg ttcttcttct tcttcttctt cttttctact
     2821 catcaactct cctgactgaa actcacccac tggaacctcc acatgcaagg agtacttagt
     2881 cgcagtttgt gaaaatacta cgcagtgagc gctaggttta aaatgtgatg gagcgatcct
     2941 gcatgggcgc ataatctcac accagttatg cgccaatcaa ttgggaaatt ctaaccagca
     3001 atcctggcaa aaccttacgg ggaggcgctt tccggcgatc ctgaacgagg ggatgaacag
     3061 gataatctgg tgcacataag tgtgcactct catcctacga gtccacatac tcgtgtgttc
     3121 cctaggcagt ctaagccgga cgttacgtgc atagccgcgg aatgccaaag gaattattgc
     3181 tggcattttt accgcaccac atccttggac gcttatcggc actttgatcg gcacaaaagt
     3241 acgggtatca cacgtatcgt ttcgtaaagc gaaaggcacc aatgtccgat gtgtggtgca
     3301 tcctcacccc tgtatacgtg tctcccgcag gtagcactag gttgggcggc ttcggggaag
     3361 gcgcgttgaa gaaaatgttt agcctggtct tgccctcgcc gatcaatttt cgacgatagc
     3421 gccacatcgg acaatacatt ttcccggata ccgttgacgg atgatttctc gattcacgga
     3481 agagaagaaa caacaaatcc tgaaggaggg gcgctccaaa ggggggatcc agcatgtatg
     3541 ccgaaaatac ggcatttccg tcagcacgtt ttatcgatgg agagcgaaac agggttcccg
     3601 agtggtagat cccgccctcc atctgaggtc tttgcaaatc gagaaccgac gactgaagca
     3661 tcgagtcgcc gagctgtcat tagattacaa cattcttcga tcagcactaa tcagcgatcg
     3721 tggaagtgaa tgttaactcg tgccgaatct ccgatggcta ttggtttacg gctatgaaat
     3781 cgtcaaggaa tgacggtcgg agaacagtgc ggcatttggc ccaggtttta tttcggcgga
     3841 ttcctttgca aggctcggtc gcaatcgcgc cattgagatt gagtatggag caaatcacat
     3901 gaaagccgta atcatggacg gtgctccgtg ggcaggaacc atgctggcgt ttcctgtcgg
     3961 aaacgaattg ctaattgatc atttgctctc agcggtaaag cggctgggca ttcgcgaggt
     4021 cgccgtcgtg tcctgtgacc aagattccta cgttcgtgac ttggtgtgcc gcgccgggca
     4081 ttcgtatggc ctgacggtgt tgtggcgtac tgagcaagtc tatcggggca ctgcgggtag
     4141 tttgcaggcg gttgaagact ttctcgatac gccgacgttt ctaggcattc acgctaatgt
     4201 ctatttgcgc gacgtggatt tggcggccgc attcaaggcg catgatgagc atcgcgcaga
     4261 tatcacgctt gtcactcagc ggatggccgg tactgatgac gatctcgaaa gtgtggaggt
     4321 tgatcctgcg ggccttgttt ctagggtcaa tattttgcat tggtcgagga atcgtcggag
     4381 ccagttgacc ccttgtggtt tgtacgtctt cagccgggag gtcctatcac agattccccg
     4441 cgatgagtat tttgatgtca atgagcaact cgtgccgctg atgcgaaacc gtggaggtgt
     4501 gattcgtgct catcagatcg agggcggcgt acataccatt gtcgggcctg acgactttct
     4561 ttggctaaac cgcgagatct tgcacaagga tatacagggc agtgggcatg ggaacggtcg
     4621 gctcggtggg gtggaggata ttgtgattgg ggaaaattcc gagatttccc cccactcatt
     4681 tctgcttggc ccgctggtga tcggccccaa ttgtgtggtg gaagactatg tgcatttgat
     4741 tggcccagct gtgatcggtc caacctcgta tttggaaaag ggaagtctcg tgcgagagag
     4801 cgtcctcagg tcggggacaa gggtgcaagg gaatgccagg gtcgagtact ccgtgattgc
     4861 cggagacgag acagttcctg agggcatgcg tctgcgaagt gcgttttgga gcaccgcgaa
     4921 gccggctctc tatgagccgc atggagtccc cgcgcaggtc tcctcgaaca gaatgctaca
     4981 acgatcaagg tattctcaac ggcctgcaag aaggatgcag ggcggaaccg ggcaacggtc
     5041 gatctacggc atggtcaagt ccgtagtcga tgtcaccggg gccgcagttg gactactctt
     5101 cgcgggcccc ctgatgcttc tcattgcgtg tgcggtcaaa ttggattctc ccggtcccgt
     5161 atttttctct caaaagcgct gcgggaagaa tggcaaggag ttctggatgc ataaattcag
     5221 aaccatggtg ccggatgcgg agcaacgcca gaaagacttg aaggcccaaa atagtgtcga
     5281 tgggccgatg ttcaagttgc aagaagaccc acgtattacc cgcatgggca agcttctacg
     5341 taagacgagc ctcgatgagc tgccgcagtt gttgaatgtc ttgcgcgggg agatgagtct
     5401 cgttgggcct cgccctttgg cgtacgacga aatgaagttc tgtccgacct ggcgcgatgc
     5461 aaggctcagt gtggcccccg ggctaacggg tctttggcag gtgaaggctc gcaatcgtaa
     5521 tcgattctcg gagtggattc gatacgacct ggagtatgtg cgtacgcatt cgttgtcgct
     5581 ggatctgtat attctcatcc ggaccgctcg ggtgttgctg aaaggagtgt gatgaacgtg
     5641 ccgtacacga ctgggctccc cgacgtagac tctacgcaga ctgtcggtcg atcgtcattc
     5701 ggcgtccgag agcacctcat cacgatcttc cgccaaaagc ggaagttact tacaattttg
     5761 ggaatggcaa cccttgtggc ggggccgggc tcattcttga tgacaaacat ctatagtgcc
     5821 gaggttcgat tgctcatcca gaatgcgcga accccgttca gcatgagcac gccgttgacg
     5881 gggcaggtgt tcactccttc cgatattact caaaaagatg acgtcgcgac ggaagtgcag
     5941 attttcacta gcccgattct gttggataag ctggttgact acttcggaaa tgaacgagtg
     6001 cttgctgcca tgcgagggcg gtgggactgg gtcggtgaaa tcccgaaaac cgttttcaaa
     6061 cagttgtccg ggttgccgcc ggtggccaag ttattgacga cgatcgggta tgttcccaag
     6121 ccggaggatc tgcactatca agccgtgcag aaaattcggg cgcatttgaa tgtggaagga
     6181 gtgcggcaaa cgcacgtatt tgtggccagc ctcgattccc ctgatccaga gttttccgca
     6241 gatgcgctca atgcgctggt cggcatctat atggatcacc agctatcagt ccgcaaaggc
     6301 aagggtgcgc gcgaattctt tgacgagcag acgaagcaga tgcgcggcga gttacagcag
     6361 gcagaactcc ggttacaggc ctttaaagac aaatggaaca ttgtctccat cgaagatcaa
     6421 aagcggcatc tcctgcaaca agtgacgcac accgaagccg cacttcgtga gagtcaggtg
     6481 caggtcgcgg aaacggaagt gcgcatcagc aaactcaagg aacgcctggc tgggcaacag
     6541 gaagcgattc cgcttacgaa cgtctcggag cgaaatccca tgctggatca actcaagaac
     6601 cggttgatgc agatggagtt ggagtattcc cagtatgtcc ccgacagtcc ggctgccgca
     6661 gaacttgtgc gagaaattgc cgcggtgcgt gcgcgcctgc aggcggagag ttcaaaggtc
     6721 accggcgcag ccacatccgg cctgaatcaa aactatcaag aattgaaacg caccctggtc
     6781 atggaagagg ggcgtcgaga aagcttgcgg ccgcgccttt ccgagctgac caagcaattc
     6841 aaatcctacc gagattctct caataccctg gatcagcgag aaatggaatt gcagggactg
     6901 atgcgggagg tcaaggtcaa gcaggaagcg ttcgacatct accttaagaa ggaggaagag
     6961 tcgcggatca atgaagtgct tgatcgcaag gggatttcga acgtcaatgc aattgagcat
     7021 gcaacagctc cccagaagcc tgtacagcca cgtaaatttc tcaatctcgt gatcggtctg
     7081 ttgatcgggt tggtgggggg attcgggtcg gcctatgtat cggagtatat gcgtcgaacg
     7141 ttcgttaccc gcgaggaggc ggaagataac ctcgggcggc ctgtccttgc tgccttaccg
     7201 ctcgtccgtc cagacacgtc cgatgccggg agttttgact tggaactccg ccaagctgca
     7261 cagcacgtca ttcgttccta ccatgagcgt ggtctgagaa cattgcttgt cacgagcgcc
     7321 ctccgcggcg aaggccgatc acatgtggcc ggcgccctcg cgcgagtgct ggccgagcag
     7381 aagtttcgcg tgctgcttat caccttcgaa gaagccggcg cagagaagct aaacaccggg
     7441 gatgccgctg cgggggctaa gcaagcgacg gataccggcc ggttccggca ggatattcca
     7501 gaggcaaccg atcgtatcca cctccatcga ttactggttc gccacaggga aggaacggcg
     7561 ttggaatttg ccgagcatct ggcggaggtc gccaagacca tgcgcgatcg tttcgattta
     7621 atcgtgatcg acggccccgc attgacctcc tttcctgaaa tgcgcgtggc cattgcaggc
     7681 attgatggca ccattttggt ggtcgaggcg gagcggacgg tgtcggtggc ggcggccaga
     7741 acgacgacgg cgatcgaagc ggccggagga cacttgctgg gactcgtgtt gaacaagcgt
     7801 cggtacatta ttccggaatg gatttacggg cgatggttgg cggcaggcgg gagggagggc
     7861 gtatgagtga atcgatagcg ggtgtaatgc aagtcgatga gaaaatagtc cctgcggagg
     7921 ggttcgttcg agaagacggg tggtatgcgc cgtatgacta ttggctcacc ctctggggac
     7981 tctacgacct ctacgcctat gcgctggcat tgcttggtga cgtcaagggc aaggttctgc
     8041 tggattgcgg ctgcggtccc gggcacacgt ccgtgatgct ggcgaaacgc ggggcgatcg
     8101 tcaccgcgtt tgatacggcg gacggtcaac tcgatacggc gcgaaggctg gcacaggcca
     8161 acggtgtcaa tgtgacgttt ctttgcaagc ctttcgagga gttggatttt ccggacgaga
     8221 gtttcgacgt cgtcttcggc acattcgtct tgcaccatgt ggatcttccc aaggccagcc
     8281 agcaattggc tcgcgtcttg aagccggggg ggaaagcggt gttcatcgaa aactccgcgc
     8341 tcaatccgct gctcatggca gccagaagca aggtctgtgg acggttgggt gtgcctcaat
     8401 acagcgacga tcatgagcat ccgcttaccc gtcgcgacat tgcgacgcta cagagcgcct
     8461 ttcccggcgc ttgcaccatt cattttccga gtttcctctt ctttcgattg ctcgatttct
     8521 acgtcttcaa gaaacggtgg tcgtggatga cggccctgct tcgacactgc gatcaactcg
     8581 ccgggtcaat tccaatcgtg cgtcgatacg gctatctgca gatcgtcgag ctgggaaagg
     8641 gccaaggtcg tgcgtagcaa accgtccaaa ttcggacggg gattttgctg tgcattgttg
     8701 ctcctgtccg ggctcttctt ggtggcgacg gacgcccggt ctgctcctgc gaccgaggcg
     8761 gtggccggtt gtcggaccga ggcgcctgcg ttgaaacacc atcgtgcgtc cgctgtcgat
     8821 cgtgtcaccc tgacttcgcc ctcgaacggg gtttacatcg gcttgtatag catcggaacg
     8881 attccggaag accggttacg gtttactgcg aagagcgggc atcggcctgc cattgtgttc
     8941 acctttcatg attgggtctc cgacgacgat tggaccgcat cttcgccgca tttcaggact
     9001 ttcacggatc cgttggaatc gtcccggctc agtccgctcc agctggccga gcaggtcaga
     9061 agcgaggggg gtgtgctggc ggttgcctgg gccatccagt gttgcgattg ggagtcccac
     9121 ctgttctggt atggatttcg taaaccgacg gtgacggttg atcgcctgct tcgaggtgat
     9181 tttgattcat acatcaccag cgtagcccgt cagatcaagg cgtacaggca tccgatcatg
     9241 cttaccctat tcagcgaatt caactatcag gggatgatgg ggttcggtaa ggagggcaga
     9301 acgcgactcg atgatgtcga tcacgtgtgt cgactgtatg gagatccgac atggccggac
     9361 gggccggaac ggattcggga cgccttcatc tacgtcatcg atcggtttcg aaatgaagac
     9421 gtgcgaaacg tgacctggtt tatgtacgca gggtctcatt atatgaatcc ccagcatgag
     9481 gactattccc catggttaca cccacaatat ttctatcccg gcgacgacta catcgactgg
     9541 gtggggcaga gcgcgtattt catcgatacc cggtccgttc caaaacttcg acagcaggaa
     9601 ctcgctacgt ccttcgcagg ggcattgggg cctgggtatg ccgcgtgggg cgcagtgact
     9661 gatcggccgc tgtttctccc tgagttcgga gtgttgggag ataagaccag cagtcgtgcc
     9721 cgggtaatag aggaagtgtt ccgcgacgtg ttgccgcagt tccctcgagt gcgggcgatc
     9781 accctcgctg atttcaaaat tgccgaggat tactacgaag tgcccaggtt cggcaccttc
     9841 gaggatgaaa cggaagcctg gaagcgggcg gttcgtcaga accctcggta cctcaagcaa
     9901 gcctctttca aaggcggaga gtaggccggc aatggcgctg aagcgatctt cgcaatggct
     9961 gtgtctctgc gcgatttttg ccgtgtgttt cactctgcgt atcggcgtcg gcggggtcat
    10021 cgacgcgacg gtatcggttg tcaaacgggc ggatgtgtac tcggacattg cggtgaatct
    10081 ggcgcgcggc cacggttttg tcgttgtagc gggtggcgag cctataattt ggcgcgctcc
    10141 gttgtatccg gcatttttgg cgcaggtcta tgcgctcttc ggggagtaca gtgaaacagg
    10201 agtgtttctt gcgcagtccg cgttggattc gttcaccgcc gtcttgatct tttatatggg
    10261 cactcgcttg ttcagtgaaa ccgtcggatt gctctctgcc gtgagttttg ccctgcatcc
    10321 gctgtccgcg tattactcac ttcgattcct gtctgagccg ctgttcacct tggcctttac
    10381 agccctcatc tcggcttgga tcgcggcaac gactacccgc cgtctcatgg cctacacggt
    10441 cgtaggtgcg ttgatcgctg tcgcagcgct ggtgaagccg gtggctttgg gcttgtggcc
    10501 cttgcttgcc acctgcgccg tatggcagtt gcgggacgaa ccggttcgcg cactatctgc
    10561 tgtgaccggg ctgacccttg cttgtctgat ggtgttggct ccttgggctc ttcgaaacta
    10621 tcgcgcgacg ggcgaagtgg tggccgtggc aacgggggga ggctatgctc tctggcttgg
    10681 caatcaaatg gtaagtgagg gcaaggagga ctgggaagtt gatgaagtga cccgggcgca
    10741 tctgttcgaa cggcgtggca cggtcatcac aggggctcaa ccgtcggatc acgctctcgc
    10801 tggttatccg tcgatccgat cggcaacaca gccggttcac atttcggtcc ctgaagatca
    10861 tgcatttttc atagctgcct ggcgggaaat gagttcccat ccgttcgaca cggcactatt
    10921 gacggttcgg aaattctttc ggttctggtt caggattttt cttcctgaca atcgctgggc
    10981 acaatcctac attgtcgtgt ttcaaaccct cttcctgagc gtggcggttc tgggcatgct
    11041 ggaggcgaaa cggcagggaa tcacggtgtt tgcgttgatc ctgccggtcc tattcctcgc
    11101 ggccgttcat gcaatgacat tctccaccat tcgctacagc attccgacca ttccggtctt
    11161 gagcatcttg caggcggccg gcttgcgggc gatcgtgcat gcactgaatg agcgatgggg
    11221 tttgtcgctt ggagtgtcct gggtccgttg gttaaaggct gcgctggtcg gctcagcggc
    11281 aagatcgtac cgggggactg cgttatgacg gcgcctgcga tgctgaaaag ctgtgccgag
    11341 agtaggaacc gctgatgaaa ccgattcgag tcgtgatcat tcgcaactgc cgtgggatta
    11401 ccggcatgac gggaggagaa acctatcttc tttctctctt gaagggattc gacccacaga
    11461 aagttcgttg cctcctggta tgcatcgtca atcccgcact tggcgaaacg tcttggctta
    11521 gggaattgaa gcagaccggg tttgagcacg tgacgattcc gatcgggaat cccttcaacc
    11581 tgagcgatgt ctataaggtc tcttccttga tcagatcgta tgaggcagac gtcgtgcacg
    11641 ccctggacca ccgctcggat ctgataggga tactcagtgc gcgtctaacg ggacgcccgg
    11701 tgctggcctc gtttctcgga tgggtcaatt tccctaaagg gtcctggcgg gcgaccgttt
    11761 atccatggat cgatcggatg attctcaagc ggttggatgc agtgattacc gattcggtgg
    11821 cgattggcac agaattaaag atgcgtgagc aagatccgcc tgtggtcgcg attcgaaatg
    11881 gcatcgatac caggtggttc gatcccacgc gtacgctcac gccgttttct caggaaagct
    11941 ttctcaaggg tggccatttt gtgttcggca tggtgggccg tattcatccg gtgaaggggc
    12001 atctgaactt cttaaaagcg gcgcgaaccc tgcttgaaac gcacgcagat tgtcggtttc
    12061 tcatcgtcgg gacggtattg ccgggatttg aacactatcg gcagggcctc caggacttta
    12121 tccgcgaaca agggttggag caatcggtgt tgatcaccca cgtgtcattg gcggagatcc
    12181 ctgccgtgtt tgccggcatt gatgtgttgg ttgcgccgtc cttcgccgag agtttcagct
    12241 ttactctact cgaaggcatg gcaatggaaa aagccgtggt gagttcagag gtcggagggg
    12301 ccggtgaaat gatcactcac ggcgaaacag ggtatctgat accggttgat gacgtctccc
    12361 ggttgaccga aaccatgcgg atgctgaggg ccgccccgga aaaagtgcgg gaagtgggtc
    12421 tgcgtgcgcg caagaaaatt gtcaacgacc tggggatcga ggcgatggca gcgcgaacgc
    12481 atcaagtgta ccgcagtcta atcgagttta agggcaagac gtcgggcggt gcgggagacc
    12541 aaggtcgatt gcgcgagcag ctggccatga tcagcgccaa gtaacccatc gcaggaactc
    12601 atgatggacg tattgtgact atgaaaattc tgattaccgg ttctcagggg tttctcggca
    12661 agagtcttgc tcactatgcc gtcaggaacg gacatcatgt gttaggtgtg tcgcggtcgg
    12721 acgccgacgg tttgattgcc ggaatggaat ctatacgctg cggcctggac caggcaggct
    12781 ttgtcgacgt actcaatggt tttgctccgg atgtcgtggt ccatgcagcc ggttctgcgt
    12841 cggtgggata ttcgtttcaa cagccacgag aagattttct gatggcagtt gaaacctggg
    12901 cgtcggtctt ggatgcagtg cgcaaggcag agggaaaccc gttggtgatc tttccatcga
    12961 gcgcttccgt ctatgggaat ccgactcggc tgcctgtacc cgaaggtgcc gggcttcgac
    13021 caatttcgcc ctatggattt cataaggtca tttgcgagca gttggcgcaa gaatatgccc
    13081 actgcttcgg gttgaacgtg gtctcggctc ggttgttctc gaccatcggc ccatttcagc
    13141 agcgcttatt ggtctgggaa ctatttcgcc aagcgatcga tgccaacccg tacttgacca
    13201 ttcagggcac agggacggaa acccgtgatt ttctgcatat cgacgatatt tgtcggtatt
    13261 tcctgggtat cgcagagcgt gagccgaaag gattttgggc ggtgaacgtc gcttccggcg
    13321 agtctacgtc ggtgagaacg atggcggaaa tggtgacgcg ccttgtggga agtacccagg
    13381 ctatcgtcac tctgaataag gatttgccgg gtgatcccaa acaatggcag gccgatacaa
    13441 cgctgttgca agaactcgtg ccgtatcagg cgccggacat cgccaacggc ttggaggatt
    13501 gtgtgcggca ttggttgtcg gagccgtcgt tgtcggctca acgggagctg cgttgtagtg
    13561 tggaggggca ctcctgaacg ggcggtacgg gataaagatc acggtgccgt gacggctagc
    13621 tgctgccagg gtacggttgt gtgtgccggt tattcagtgc gaaggggatg gtgtaggcgg
    13681 acatgcaggt gttgcgttcg agtatgaagg cgttgtcgca gcagaccgcc gtggtgtttg
    13741 ccggaaaaat gaccggcgcc tgtctggggt ttgtgatgag cctgcttgtc gcgcgttgga
    13801 tgggaccgga ggagttcgga ttattttccc tgttcatcgt gatcctgatc ttcggcaatg
    13861 acgtgcttgg cgacgggttg agccctggag ttgtgcggtt ttattccatg tatcggcgtg
    13921 ccgacccctc caaggcagct gaagtgctca ccaacgcgct tgcgttgcgc atgctgctcg
    13981 gcattccggt ggttgtggtc ggtgtagccg tgggatcgca atatgcggct agggtgtttc
    14041 atagccagtt gtacgtgctc cccgtagtct tgggtctagt cggctccttt ggtgcggcct
    14101 tgtggagttt caacctctcg gtgtggcagg cccgtgaaga gttcggtacc tatggggtga
    14161 tggtcgcgct gataaatgtg ctgagggtcc tcagtctacc gttgttgttc ctgggaggat
    14221 atctcacgct gggcggaatc atggggtccc atgttctcgt ctatttcctc tgtgcgctgt
    14281 cgggtacctg ggcactgcgc aggcatctgg cacatgttcg cgttaacggc gaattgttgc
    14341 gggaactgtt tcgattcagc aagtggccgg cgatggccag tctctgtttt atcctccaag
    14401 tgaatctggg cgttccggtc cttaactatt ttgtgaatgc ccgtgaagcc ggcctgtatg
    14461 gtgccggatc atcactcttg atgggagtgg attttctgac agtcagcctg ctgacgacat
    14521 tgcttcccaa ggtcagtcag ctgaccggga ttgaacagtg tcgttcctat gttcagcgct
    14581 catttccgat gtatgcactc attgccgctg caattcttcc gttgctgttt ttcgcacggc
    14641 cggtggtcat cggattgttc ggttctgcct atgaaggcac gatcgaggtc tttcaggttc
    14701 tgtttgtcgg aacgttagga accttggtga cgcatccttt gtatctagtg ctctatacga
    14761 tgaatcgccc gcacctgcac acattgtcag gaattgtagg actgattgtc tggctgctag
    14821 ccggcttctg gcttattccg caattcggtg ccgtcggagc cgcgtggacg acgttgtgct
    14881 cacgacttgt tcaatccctc atgatcgttg tcatcctttg gcatgccctg ggattgggcg
    14941 gatcgtcggg cttggcgcgt tcggttatgc cggatgtgag aggatcatga aaccgagcga
    15001 tcagacgtat accattccga ctctgctggg cgcgacgctg ggcgcatccg tcttggcgct
    15061 ctcgaccaaa gctcttgcta ttgtcattgc ctgcagtgcg tttctcagta tgaccgcctc
    15121 ggcagttttt ccttattaca tactggttgc caccattcct gtacaggttg atttactggg
    15181 aggactgacg gtcacaaagc tgattacccc gttggctata ggtatggtga ccatcaatgc
    15241 gctgatccat cgaggaccat ggccggtgct gttacgatgg ccggccggtt atcttgccgg
    15301 cgcgttcttt cttgcctctc tcttgtctct cgtcctcgcg gagggcttac gtggactgcc
    15361 aggcgaggca gcaaagatcc ctgtttacgg ggcgctcttc tttttcacac ttacatttaa
    15421 tcgccatcca gaggatatgc gccgtctgct gtgggtcatc accattaccg gtgtggggga
    15481 ggcactcatt acagcggctc aggtccacta cggttttgtg atgccgggcg actggcggag
    15541 aaacgtaggc ctgccaagcg aaggcggtgt agacggcgcg ttcatgtcta tttccgaggg
    15601 aaaggttcgt gctgagggta ccaccgccca tcccattttt ctcgcaagtt tcttcctgat
    15661 gtccatgccc tgcaccgcat tccttctttt tcaggagaaa catccatggg tcaaggccgc
    15721 gctgggggcg atgctgagcc tcatggcata tgcgtggttt tacacgtttg ctagaagttc
    15781 ggttatcggt ttcgccctcc tgattctggt tggtctgtgg ttgcaattca aattcgtgag
    15841 aaagctgtct cttattgtgc tggtgctcgt gctcgccgga ggcttgagtt atcaggttgt
    15901 ctcggaatgg tttcaagtcg gagtgcaaac cgtagagaat caaaacctct tcggtaaggc
    15961 agatctcaac gaaggcagcg ggagttttgc atttcgacgg gagtccattg tgggtggctg
    16021 gaatctcttt ttggcgcacc cttggtttgg tgtcggcttc ggacaggcca tcaatcatta
    16081 cgtcaaatat ttgccagcat gggccgacca ctactatcac cctgctgtga tccacaatat
    16141 gttccttgaa gtggcgagtg agcttggcgt gttttcattg tcggcattca ttggtttgtg
    16201 ggtggtggcg ttcgtcagtc tgaagcgggg gcttcggatt cccgatgtgc gaccctacgc
    16261 cgttctgttg agcagcatcc tcgcggggca aatgattttt ctgatgatca ccccgatggt
    16321 gcgagagatt tggctgacat tgccgatggc catcgccatc ggacatatgg ccaagaccca
    16381 cacgcgggcc acgttcggca taccctttcg acaggtgggc gctcgtgctc aactacgacg
    16441 gatcgttgat cgtgggaatg gcctgcctgc aggcctgagg tgaggacatc atgaaaattc
    16501 gcgtcagtgt cgtcattcct gcctacaatg ccacgaaaac catcggcgat ggcctggagt
    16561 cctttgctcg tcagtcattt ccagcagccg aagttgagat catcattgtc gatgatggct
    16621 cgacggacgg cacgccggaa tatctggaaa cctatgccag gagctgggga ttagcgcagc
    16681 ctcgattgcg tgtgatgcga caggctcatc aaggcccggc ggcagcgagg aaccttgggg
    16741 cggcggcggc acaaggggat tttctgttgt ttacggatgc cgattgcgtg ccgcatgtgg
    16801 attggatcaa ggaaatggtg gcgcccttcg cattgtcggc gattgccgcg gtgaaggggg
    16861 cctacaaaac aaaacaacgc agtctcgtgg cgcgctttgc ccaggccgag tttgaggccc
    16921 gctatcgtca gctcgctgcg acggaatatg tcgatgtggt cttttcctac tccgccgggt
    16981 ttcgtcgtga ggtgttccgc tctatcggag gattcgacac gagtttcccc gtcgccgata
    17041 acgaagatac cgatctgtcg tatcgggtcg ccacggccgg ctacaagatc aagttcaatc
    17101 cggcggcgat catctatcat caacatccgg cgacgctcaa acagtatctc cggaaaaaac
    17161 atagccgggc gtattggcga gtgatggtgt acaagcggtt cccgggcaag gccattcgtg
    17221 attcctacac gccgcaaacg ctcaagcttc agatcggctc gatcgtgctg gctgcggggg
    17281 cgatcgcgtt tgtaccattt gtgcctcatg ccatgtatgt ggcggcactt gcgggcggac
    17341 tcttcacagc cacagcgttg ccgtttctat ggcagttgcc tcgagaggat ccgggattac
    17401 gactggtcgc gccatttctt ctagtgtgtc gggcggctgt catggcttca ggtttgatgc
    17461 gaacagtgcc gttactcatg agcaagacca attgagactc atgttactga gggggagaca
    17521 agacatgcga cgtattttgc acacaagctg ggctgtttgt ttcatggttc tgtgtctggt
    17581 gaccactgtg caggcatccg agaccgaggc ggtacttact ccgtctgtgg atgcgggctg
    17641 gagtggtccg tttcgaatag gtgcggggga tgtcctcaat gtattcatct ggaagcacaa
    17701 agaactgtcg actattgtca ccgttcgtcc cgacggaaaa atcaattatc cattgatcgg
    17761 cgagattgag gccaaaggac tcacgctggg tgagatcgag gaacggatca ataagcaatt
    17821 aaagcagcac atccaggatc cacaggttac ggtgatcttg gaggcgacgc atagtttccg
    17881 catctttgtc ctgggtgaag tgatgcagcc gggtgtcttt gatctcaagg gaccggtcac
    17941 cgtcattcaa gcgctggcca tggcacgggg attgaccacg tttgcgtcgc ggaacaagat
    18001 ttttatcgtc aatcctgcgc gcggtaacga ccaacgcatt ccgtttagtt acagcaagtt
    18061 tgttcagggg gaagatacga atcagaatgt gatgcttcgg cccggggaca cggtgatcgt
    18121 tccgtagtgt cagtggaatt tcaacaatcc gggacgaaag cgaagttgag tgtcacacag
    18181 aatggaatgc cttgtcacat ccgggagtcg cgtgagcagg cgaggtatcg ttttgaacag
    18241 tgcacgaggt ccgattgggc ggactttccg ctggttgcgt attgcggtgc ttggaattgc
    18301 atcggctgca ggtgcagtag tgacctcgcc gatgctcttt gcgcaggagt cggacaactc
    18361 ggagtttgtc cggccacagc gcgagttcgg tgaattgcca tcctggcaga atcaggtgag
    18421 ttatgaccgg atgccggcgt cggaaaaact gctcctaggt gctccgattc gccgagatgg
    18481 gtttacgcct cggctcacgg tcactgaaga atatacggac aacgtcttct tcacggcgaa
    18541 gaatcgcggg accgactaca ttacgaagat tgcgcctgga ctgggttacc ggacgtctgg
    18601 gcgagacggg caactctctg cggattattc ggtcgagtcc agggtctatg cgaacaacag
    18661 caatcagaac agaacggtgt cgcggcagaa tggggagctg ttcggacttt ggaatttatc
    18721 cgatcgaacg tcgctgacct tgtttgatcg ctttgaatca ttccaagacc ccacggaaca
    18781 gcaggtgccc ggtattcttg gcgcatttgg gcgcacctcg atcaatatcg gggctttgat
    18841 gatgaggcat cgactcactc cgtccgttga tctgctagcg aattatggaa attttctctg
    18901 gtctgtcgat gcgccgggtg ccatcaatag tatgacacac gaaggcgagg tgggcgcgag
    18961 agtacgggag acgcagtggg ggcgtaccac cgtaaagtat cggtttcgat tctttgattt
    19021 ccagcagggg cgtgattttc agtcccattc tgcgctggtt gcccaggaaa tcgacctgtc
    19081 tgagacgctc gttgtgagcg ggacgatcgg tgcggttcgt gtggagccga atccttcgac
    19141 ggtcgaagtc ctcgcgcagg cgtcgatcaa gaagtcgatc ggggacgcgt tgtatgaact
    19201 gagttatatg cgcgatgtgt ttcctccatc gggaggactc agtcaaccgc tggtcggaga
    19261 ttttgtacgg gcgacggcaa agatacgact tgcgaataac tttctcttcg atgccggact
    19321 gacgtggatt ttgacgagca ccaattcaga tgatttgacg gtacacacct tgaaatggaa
    19381 cgttggcatt tcgtatacgc cggcctcctg gcttgtggcc cgactggggt acgacatgtt
    19441 cgaccagcgt gaagacattt tgggcacgtc cgccagccgc cttgcgaaca aggtcagtct
    19501 gcggatgatc gcgacattct gagggtgtgc atacgctacg gaattgatga catcgggtga
    19561 gactccgagt gcagagcagt aaggtgggtg aaaatggaac cagtgagtga cggacttcgc
    19621 attcttttta tcgcgccggc tccgcgcgcc gggacggtgc aatataccca caacctggcc
    19681 aatgcgctgg tggatcgggg gcatcgcgtc acgctggtca caggtgttgg attcgaattg
    19741 gccgactatc cgagaaagta tacagcgtta gaagtatttg atcggtatcg gcccaggccc
    19801 ttgcggctct gtcggtttgt ctggcattgc ctgactttcc ggccgcagat tattcatcta
    19861 caaggggcgc aacatccggc cttgtacatt ctgctgtggg cgatgttgcg gctcttgggc
    19921 agcgcgtcgt tcgtctatac gcctcaagac gtcttgccca attcattgcg ttcctatcat
    19981 atccgcgcgt ttcgttttct ctacgcccgc atgcggcatg tgtttctcaa tgccaaacag
    20041 aatgagccgt tggtcatcga gcattttgcg gtgccgcgtg accggatcac ggtgcttccg
    20101 attgccgatc tcacggcgtt tgtgcgggaa cacgtggccg gtgagtcgcc ggacattccg
    20161 gccgcgtcgc gggtggtgtt gtgcttcgga ttgatcgagc cgaggaaagg gatccatacg
    20221 cttctctctg ccgcgccgga ggtgcttcgg caggtgccgg atgctctgtt actgattgtc
    20281 gggaagccgc tgatggacat tgcgccgtta cagcgacagc tggccgattt ggggttgcag
    20341 ggacgggtgc gattggtgcc gcagtacgtg agttttgcgc agatggccgg gtatttcact
    20401 gccgccaggc tcttggtgct gccgtacgaa aacggatgga atagcggcgt cttggcgtct
    20461 gctttcggat tcgggaaacc cgtgattgcc acgcgagtag gcggattcga cgaggtcgtc
    20521 agcgacgaat cgacggggtt gctcgtgccc ccgaaggatc cggcagtgtt ggcgcaggcg
    20581 atcgttcgcc tgttgcgcga tgatgcgctg tatgcgcgca tggttgtgaa tgtccggcag
    20641 gcagccgcag aaatttcctg ggagacgatt gcacggatga ccgaagctcg gtacggggac
    20701 gtcgtgggga ttggagcgga ttgtgcagta tcgcaagctc ggtaataccg gtctgacgcc
    20761 gtcggtgctg ggattcggat gttcgatgat cgcttcgctg gcgacacggt attcgcccag
    20821 cgaagtggag gcgagtcttc gtgaggccag ggaggcgggg attacgttct ttgatacggc
    20881 cgacgtctat ggtcagggtg atagtgaacg tctgctcggg aagctgtttc ggcgcggggg
    20941 cgaaggaatg attctctgta ccaaggctgg gttgacggtc gggtcgatgg aacctgtggt
    21001 gcgagtggtc aagccggtga tgaattcgat cctgcggcgt tggcggactg cacgagttgc
    21061 gacgacgcag gcgcgccgcc gccaggagca gcagtgtttt gacccggact atctttccgg
    21121 acgaatcgag ggaagcttgc gccggctcag cgtggatcgg attgatctct ttctattgca
    21181 caatcctccg gttgatcttc cgcagcgtga aggagtgttt gagctgctga cccgcttcaa
    21241 ggcgcaaggc aaactgcgtt ggtttggcgt gtcctgccgg tcgttggacg acgcctacga
    21301 atggctaggg cagcccgatg tcgcctgcgt gcaaattccc gtcgaccgca gtcgaatcga
    21361 ggcagcaatc ccggtgttgg aacgcgcacg agcccaacag gtgggcgtga ttgcacggga
    21421 ggtattcgcg caggatgcac tggccaaagg ctccgtgtcc gatgcgttag gtccgctggt
    21481 ggaacgtgcg gagattggcg tcgtgctcgc gggtatgagt tgccggcggc atgtgcagga
    21541 aaatgtgcgt gcgctggacg tcgcgatgag gtgtagccat gttgcttgat gcgcgatcga
    21601 tttccaacgg agccatcctc accgctgatg tctgcatcat aggcgcaggt gccgctggta
    21661 ttaccctggc gatggaactg ctggccactg gtctgaacat tatcctattg gaagccggcg
    21721 ggaagtcaaa agccggagag agtcagagcc tctaccaggg agagttgaac gatccggtcc
    21781 gacacttgcc tttggatcag gctcggtatc gccaactcgg tggcacgaca tctctgtggg
    21841 ggggacgctg tattccgttc gattccctcg atttcgatca acgcgagtgg atctcgcaca
    21901 gcggctggcc gttcccgcag aaggagttcg acggctatta ccggcgtgcc cattcctact
    21961 gtgagtgtgg agagtacgat taccgtgtgt cgaccgcgct ccccggtgcg ccgccatcga
    22021 tgctgccggg gttcgaggac ggggatgtga atacgtcggg tatcgaacga tggagtccgc
    22081 cgacgcaatt tgggaaagtg tatcggccgg ttctcacacg tgcggacaat ctgcgcgtac
    22141 tgctgcacgc cctggcggtt gaattgcaga cctcatcgga cggtaagcgg atcgattcgg
    22201 tcgatgtggc gaccttcagc ggccctcgct ttaccgtacg tgcgcgcacc acggtgttgg
    22261 ccggcggcgg attggaaacg acgcgattgc tcttggcatc tcgaggtgtg catcgggagg
    22321 gaatcggcaa ccattcggat tggttgggac gcgggtacat gtcccatatt cacggcgtca
    22381 tcgcgagtgt cacgctcacg gcaggacagg atgtcatgtt cgggtacgag gccgatccgc
    22441 agggtgtttt ctgcagacgt cgcatcgcct tctcggaaga ggcccagcgt cgacaccgtc
    22501 tcttgaatct gtacatgctg ttggatcggc ccttggtggg ggacccgggc cacggcaatg
    22561 cggtcctttc cgcagcgttt ttgctcaaac gtctgttggg agggaggcag caggaggagt
    22621 tagggaaggg caagtactca ctctattggc ggcatatcaa gaatatcctg gcgggctccc
    22681 cccaggcatt gtcggtactc ccaaagttcg gtcgaaagcg gctgctccag cgtcgacgga
    22741 ttccttcgct gctcatgcgg tcccgctcaa acacctatta cctctacttc cagagtgaac
    22801 aggtgcctca ttgggaaaac cgtgtgactt tggatgctgc gcgagatgag ttcggcacgc
    22861 cgcgattacg gcttcatttc gaagtcatgg agcaggatcg gcagagtgtg cagcgggcgc
    22921 atgagctcat tgatcaggaa ttgcggcggc agaattgcgg gtatgtgacc tatttgggaa
    22981 acgatgtgtc gcaattgatg cgcgacgtga aggcggtgct gggtcatcac atcggaacca
    23041 cgcgtatgtc ggcagatcct tcgcagggtg tggtcgacgc gcagtgccgt gtgcatgggg
    23101 tagcgaatct gtttgtcgcc agcagttcgg tatttccgac atccagccac gccaatccga
    23161 cgttgacaat cgttgccatg gcgctgcggc tcgccgatca tctcaaggca ttacattccg
    23221 gcgtcacgcg agtttgagac agtatttctg tgggaaaggg gaacattatg tattggaaaa
    23281 acaaacgtgt gcttgtcacc gggggcgcgg gtcagatcgg gtcccatctg gttgctcggc
    23341 tcgctgctgc gggcgcacag gtaaccgtgg cggacaatct atggcgtgga aagaagtcga
    23401 atctgcttgg agacgacgga gctccggtca ttgacatgga aagccggttc ttagagctgg
    23461 acctctgcga ttatcggaat tgcgagcggg cgacggaggg acaagatatc gtctatcacc
    23521 tggccgacgt ggttgccggc atcaactatg tgttcggcaa tcagttctcg ctgttcaata
    23581 caaatctgat catcgattcc aacatgctcc gggcggctat cgccaataag gtgtcgtcct
    23641 acgtgtatgt ggggacggca tgcagttatc cggccgaacg ccaaagcaaa ttgaacccgc
    23701 cgcctttcaa ggaagacgat gtgtatcccg catcaccgga gtcatcctat gggtggagca
    23761 agctgatggg agaaatggga tgtgatttgg ccagaaaaga gaagctgttg gatatcggaa
    23821 tccttcggtt tcacaacgtc tatggacccc actgcgaaat gtcgcccgag aaatcgcagg
    23881 tcattccatc cttgatccgc aaggcggtcc ggcatccgga tgaggaattc gtggtatggg
    23941 gatctgggaa acagcgccgc gcgtttgtgt tcgtgagcga tatcgtagac gccttggtgt
    24001 cagtggccac caaaggcctg aatcaggggg tgattcagat cggacctgat tacagcacct
    24061 cgattaagga gatcgcggaa ctggtgtgtg ccatttctgg aaagccgatc gatatccgat
    24121 tcgacaccag caagcccgaa ggtgatgtcg accgagcggc cgattggacc agagcgcgcg
    24181 acatcctcgg ctggtcgccc aagacgagca ttcaggaagg gctggagcgg acctatgcgt
    24241 ggtgtgatcg ccaggtgttt caaggcgtag ggcggtagga ggcggccggt ttctctcagg
    24301 tagatccagc gaactgaatg tgtggtgacc caggctggat gggtccgcgt atctcagttg
    24361 taacaacgaa gtgaggcaac atcgtgaaga aagcattgat caccggcatc agcgggcaag
    24421 atgggtcgta tctcgcagag ttattgttgg caaagggtta tgaggtccat gggattatcc
    24481 ggcgctccag ctctttcaat accggccgca tcgatgcgat ctatcaggat ccacacgttg
    24541 ccgaaccgag actacggctg gtctatggag acctcaacga tgctagttca ctcaataaaa
    24601 ttctgcgcac gatccagccg gatgagatct acaacctggg cgcgcagagc cacgtgcggg
    24661 taagtttcga tgtgcctgaa tatacggcgg aggtaacggc actggggacg gtccgtctgt
    24721 tggaagccat tcgcgaatcc ggtatccaac ccaagtttta tcaggcctcc tccagcgaga
    24781 tgttcggcaa ggtgcaggag attccccaac gggaaagcac accgttttat ccccgcagcc
    24841 cctatggcgc tgccaaggtc tacgcacact ggatcacggt caactatcgt gaggcgtaca
    24901 acctattcgc ctgtagcggc attctcttca atcatgaatc gccccggcga ggagaaacgt
    24961 ttgttacccg gaaaattacg cgtgccgcgg cccgaattaa gctgggggtg cagcaggagc
    25021 tgtatctcgg gaatctcgat gccaagcgcg actgggggtt tgccggcgat tatgtgcagg
    25081 cgatgtggat gatgttgcaa gcggatcaac cggatgacta cgtgatcgcg accggcgaaa
    25141 cgcatacggt gcgggaattt ctcgaccgca ccttcagcta tctcgatctg gattggaagc
    25201 aatacgtgaa gatcgatccg cgttattacc gtcccacgga ggtcgatttg ttgatcggcg
    25261 atgccacaaa ggcgaaaaag gtcttaggct gggagccgaa ggtatcattc gaagacctga
    25321 tcaccatgat ggtcgagggg gatctgcgcg ccgaacggag catcctcgat ggcacaagag
    25381 gagcacgctg atcatgtcgt tttggaaaga caagcgtgtt gtggtgaccg gcggggcggg
    25441 ctttctaggc acggtggtgg tcgaccaact tcggaagcta ggctgtcgaa acatcgtcgt
    25501 cccacggagc catgactatg atcttgtgga catgggcgac gtcaagcggt tgtatgtgga
    25561 tgcagctcct gatctggtgt tgcacctggc tgctcgcgtg ggcggcatcg gggccaatca
    25621 aacccatgcc ggtcagtttt tttacgacaa tcttatgatg ggaactcagc taatcgaggt
    25681 gggccgtcag caggggttaa aaaagttcgt ggcagtagga actatctgtt cctatccaaa
    25741 atatacgccg gttccctttc gggaagagga tctctggagt ggttatccgg aagagaccaa
    25801 cgctccctac ggcttggcga agaagatgat gctggtccaa gcgcaggcgt atcggcaaca
    25861 gtacggattc aacgccgtcg ttctgtttcc agtgaatctc tatggtcccg gggataattt
    25921 cgacatgcag acctcacatg tcattcctgc gttgatcaga aaatgcgtgg aggcaaagga
    25981 gcgtggtgac gacagagtcg tcttgtgggg cgacggctca ccgtctcggg agtttctgta
    26041 tgtgacagat gccgctcgtg ccattctgct cgctgctgag cattacaatg gaaatgagcc
    26101 ggtcaatctc gggaccgggc aggaaattac tattcaggcg ttggcgcatg tgattgccga
    26161 tgccgtgggg ttcacgggtg aaattgtctg ggacacaacg aagccgaacg gacagccgcg
    26221 ccgatgcctg gaagtgagcc gagccaagca actatttggg ttcgaagcaa gtactgcctt
    26281 tgttgacggt attcagcaga ccgttgcctg gttttacgcc aatcggggat ccatccggga
    26341 agtggtgttt tgactgttcc aacatcactt atctagttca tacaattcgg gtgcagtttt
    26401 ccatccgaga ggtacacgca agagagaaac gctgacgggg tcgtcgtgac gacatttttt
    26461 aatgctgtgc cttgttgtgt ccctggacga attaaacagt cataggggaa gacgccgggt
    26521 atcagccacg atggatgtgc cgaccacata gcaaatccgt ggatttgtgg atatcctgaa
    26581 ataatccgtg gtattccggt cgcaattttc tgtgccgccc agctagagtt ctgcgacatt
    26641 ccgtcaggaa agcctaattc catgaaaaat accggtttgg ttggcgccac tgtcttcact
    26701 tcttgcatga ctttgtctag agctgcgaag tgattctcga tgggaatcac gtagtcctgc
    26761 gtcattccag gccagtcctt cgcatagtaa tcgatcatgt agaaatttaa gctgatccag
    26821 tcgatgtatt gatcacctgc gtagaaattt gaaaaggcat gacagctttc tagcagctgg
    26881 cgcgcatagg ctttgtcgat ggtggagggc agttcattta cgtcatattc gatctgattc
    26941 acttggttca ctgaccatcc cattgtatca aaggtcagaa atttaaggcc ctcccgacgg
    27001 acgaagaaat catagtaata gcgttgcgcg gctttcagac gttcagttcc atcgcacact
    27061 tggggagttc caatgtcact gtagagtgac gcatacggaa gcgaagacgg attgaactca
    27121 gaaaacccgc gcttgttctc gatggcccag cgcagcgatt gatcaccagc tggtccaaag
    27181 ccgccaaaat agtctgctcc aattccgttc ggctctcgcc ctgcgataaa aaatacaggt
    27241 tttccgtatt gccttagttc tgcggcaaat cttcgaagtt ccgcgtcata gactccgttc
    27301 agcaacttat cgaccgtgaa tccctgaggg gcttcagact caccgggcgc agggtgtgtg
    27361 ttgtaggcct ggaccacgat cacttttcct tcctgccatg ccagattggc agcctgtacg
    27421 tccagatggg gttgacctgc cgcgtcgtat ccgttacccc acgagccacg atattttgac
    27481 cacagcgcag tctttcttcc gctggccgat tcaaacgatg caatatcatt ctggacccat
    27541 tcgtattggc ccatgtagag gccgccggct ggcggaggaa cgatcttcag tatcgaatag
    27601 tcacgtgcag cggtggtttg tgtcgtcggg ggtgtgacgg attgcgtttg tacctgtcgt
    27661 tttcgggaga accgagattg tgcttctgct gtagaggcgt cgaatgagat ccagattcct
    27721 gcaatgaagc tcagggcaag gactgctgca tagtgtattt tcacggtgag acctccgagt
    27781 atctggtcct tctagtgagc aagggtcgta ccatgggaag ggaaatgggg aagcccaaaa
    27841 atcaagggaa atggcaattt actcaggata tgcgctctgt ggcgaggcac attcttgaac
    27901 agaatgctgg tgggaccatt caggtcacat acacagaagg atacttgttc gtatccagca
    27961 ggtaggttct ctacggtttc tccatccccg gaatacattc agtcggcata agttcgccac
    28021 cgtgaaaatg tgagacttgt ttccatttct gcagcacggc tgcaccatcg aatgtcagca
    28081 gatattcttc acaccagatg ccgggcgcgg tgtaccgatt gccggcctgt tgttcgcgga
    28141 tttcatagac ccacaccgtc tctccctcgt cgctcttccg tactgcttta ggcgccccta
    28201 gttcctgcct cacctcagtc tgtgttgccc gccctttgac tgaatccaga tacgccgctt
    28261 ctctgttttg aaaatgactg caggcggtga tcccgatgag tatggccatc aggccgaagg
    28321 tccaagagcg tgtcatcatc tacctcccga ttcgagggtg atccggtttg gagatctatt
    28381 gtctcaggcg ggattgtaca ctgatcccat gaatccgtct gcctcatccc tcctcgcaga
    28441 tgggcggggg atgaacggcg aagaggcgca gaatgtcacg tactctagcc tggcgagggg
    28501 atagaattgt gcggtggtga taagggaacg agcggcgcga gagggcgcac ctcgagtgtg
    28561 aaatcaaatc atgggctgaa catggaaggg aagcgcggga gagatcagac cgctttttta
    28621 accagacccg accgcaggca gcgggtgcac acgcgaatac gcaaggccga cccgttcacc
    28681 agtgctttca cgcgttgcaa attgggattg aagacgcgct tcgtcttatt gtttgcgtgg
    28741 ctcacgttgt taccggtctg atgctttttc ccacagagat cacaggcaaa tgccacggcc
    28801 ctactccttt gttgcggcgt ctttcaacga ctatccttga atgggaaggg atgctaccat
    28861 agcgccaggg gtcaagacaa gctgccgggg tgaattctcc tttcaggata ccctcttccg
    28921 ctcacatcgc acgtcattcc atctgaggac ttccctatgg ataaggtcac gtttatcgga
    28981 ttactcgcag gaaccctgac gacaattgcc ttcatccctc aactccagca gacctggcgc
    29041 acgcgctccg cgcaggatgt gtcgttgggc atgttgctga cgttcatcat cggggtgttt
    29101 ctgtggttgg tctacggact gctgctcggc gcgctgccga ttatcctggc gaatctcgtg
    29161 accttggtgc tgacgctggc cattctcgtt ctgaagttac gctatcgtgc ctagtgccct
    29221 gaccggagca gcgcaggttc cccttgacaa gattggtcat gctctcctaa agtttgctgc
    29281 gttttcagac accttgggtc aagggaagag ggtgcaaaac cctcgcggtc ccgccgctgt
    29341 aaatggggac gaaacccgta tgtgccactg tttggttcgc cgaacgggaa ggcgcgggga
    29401 gtaggatgaa ccatgagcca gaagacctgc ccagggagag accctttatt ccctcgtggg
    29461 ctggggaata ggcgaggatg agtgtgcggg tgcaatcctc agggttccat gttggccctg
    29521 gggatttttt tatttgcgcg ccggtcgaat caagt
//
LOCUS       DAOQPD010000049        28685 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_741_length_28685_cov_21.197730, whole genome shotgun sequence.
ACCESSION   DAOQPD010000049 DAOQPD010000000
VERSION     DAOQPD010000049.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 28685)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 28685)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28685
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_741_length_28685_cov_21.197730"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..890
                     /locus_tag="PK063_12000"
     CDS             <1..890
                     /locus_tag="PK063_12000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glutamate synthase subunit beta"
                     /protein_id="HMZ97821.1"
                     /translation="LLRYGIPDFKMEKWVIDRRLEQMKAEGVEFKTGVTVGKDVTGEQ
                     LRQEFDAVGLTMGAEMARDLPVPGRELKGIHFAMEYLTQQNKRTAGISVSEEPITAKG
                     KRVVIIGGGDTGSDCLGTAHRQGCSEAHQFEVLPEPPPSRSSSTPWPLWPMQLRTSHA
                     HEEGCDRQWSVSTTKFTGHNGHVTKLHANRVKFEGGKFVAIPNTDFELDADLVLLAMG
                     FTGPVRNGFLDSLGVNYDARGCVTVNENFMTNLDGVFAGGDTKRGASLIVWAIAEGRK
                     MAAGINQYLQANKSAKSGR"
     gene            2080..2517
                     /locus_tag="PK063_12005"
     CDS             2080..2517
                     /locus_tag="PK063_12005"
                     /inference="COORDINATES: protein motif:HMM:NF028108.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5069 domain-containing protein"
                     /protein_id="HMZ97822.1"
                     /translation="MTQQTYPRSPKVLLGGIAHLGRFIDKVRLRHAGKIQDYNYITVG
                     FDKYLIDFLQIDAKAFEQQVLAGESDEKLLSWVKTHGRKHSEEEIAQWSKGLLAGGPK
                     DDAAKQRFQGRVQDIATKRGVPLTSLPPVTTWADVIELDEERM"
     gene            complement(2546..3202)
                     /locus_tag="PK063_12010"
     CDS             complement(2546..3202)
                     /locus_tag="PK063_12010"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97823.1"
                     /translation="MGASLLHRSIALLLFVITTSTASLLVTAEPSHAQGGGSQVTITP
                     TDSKVIAWSAAGGGVEESLQPNETVISSAARGHTGFVQTSSRLLGFSAGLRQWREVSI
                     GVEERIGRHQLLPFLILAHSNQQVFGFQETRGHWTTISLGPNETVSQLRGQGHVAVAI
                     TNERALGFSTYTGGFFNIDWTPNERVLSVDGSQNGMVVRTSSRTVIFKSQSTGWTEVR
                     "
     gene            complement(3349..3840)
                     /locus_tag="PK063_12015"
     CDS             complement(3349..3840)
                     /locus_tag="PK063_12015"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: protein motif:HMM:NF012478.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HMZ97824.1"
                     /translation="MTRVSLAGLLILCAIVLLSRPLHAQTGSPTIEDGSKVTLQMTIT
                     LPNDHVMIPPQTSEYTHGEKQLLPGLEEALVGLHSGDTKRVELDADHAFGQYDAGKKM
                     TVPRAQLPHTIARGDMATTAEGRPFTVVSLSDESAVVDFNHPLAGKHIVLDIVVLNVK
                     PKA"
     gene            complement(3896..4177)
                     /locus_tag="PK063_12020"
     CDS             complement(3896..4177)
                     /locus_tag="PK063_12020"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97825.1"
                     /translation="MKSIIVIGSLVCVLAMPIVAPLESQASLTYTRVKVESVDQASQS
                     LTFKTAEGEVWTLAALSADMLSGLHKGDTCSLEIDFDNRVTKIVKIDSP"
     gene            4389..5624
                     /locus_tag="PK063_12025"
     CDS             4389..5624
                     /locus_tag="PK063_12025"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97826.1"
                     /translation="MSQDDASFPGSESGGITVALALSAIVTLPLMGPWLSGQSLRPYL
                     EFPPLSTGVVTQVAFSWPVFVGLSALIVCLLAPFIVRVARTNSRGVSTVAGQERTPYG
                     SVRRQCVLPHAFPWWGWGAVAWTICAWFLAWTRFEWMQPWQPHTFTPLWLGYIVVVNA
                     LTYRSTGRCMLIHRPRYLLSLFPLSACFWWLFEYLNRFVQNWYYVGGGTLTTGEYLVR
                     ATLPFATVLPAVLSTAEWLTACPRLSAGLDHVVTINFSRRVWGWLLLSGAAAGLLGIG
                     LWPDYLFPLVWVAPLLVITALQLIRNEPTIFSETAHGDWRTLWAVALAALVCGWFWEM
                     WNFYSLAHWQYAVPFVQGVTLFHMPLLGYAGYLPFGLECWAVADLCLARKFAGGVAYY
                     RAAEPETDFAQRNPTVAER"
     gene            complement(5561..6505)
                     /locus_tag="PK063_12030"
     CDS             complement(5561..6505)
                     /locus_tag="PK063_12030"
                     /inference="COORDINATES: protein motif:HMM:NF015722.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
                     /protein_id="HMZ97827.1"
                     /translation="MIPRTLFPGIASLLHALSLVILSVAATWLNPALSIAARAPTPPP
                     TAELAKHLTSIAELAASSPAVLIPEGPFLLGSIRVDDDPYGMGTQFDDTELPQHRVWL
                     DAYEIDRDEVSLGEYLTYLHQRKIHPSKDLQHLIWHVITVHSVSDETLAQWPALYVTW
                     KEADNLCRASGKRLPTEAEWEKAARGPDGNRFPWGESLPDNSLAMFGQHHVHEIPILA
                     PVSSGEPGKSYYGVHHMAGNVAEWVNDWFGFDYYAYMPERNPPGPTSGRYKSLRGGSW
                     KSRPIMLRTATRSGAPADQRSATVGFRCAKSVSGSAAR"
     gene            complement(6505..7260)
                     /locus_tag="PK063_12035"
     CDS             complement(6505..7260)
                     /locus_tag="PK063_12035"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97828.1"
                     /translation="MIKASQRSLAPLFSLAVLSWCVGCTPDESPFRQENENLRKQLAK
                     QESLLNSLQDGNKVMQQQIDLLNQELRDAKKQTEHAQAEAKSLQTEAKTLGTKLDAQL
                     AESKKLSGEIQRTAAKAAQATDSIRVEEKGSQVEDLPRPLPAVAKAAEEALTRNGYRI
                     RVTVKTDQKAVFVTERKISIPTSVETAGSRNQYVVSLQALPSNVTRLSVKAEFERVAQ
                     GGRVLAVDAEEIAEIERRLIAEIGKAVASPSKL"
     gene            7400..8029
                     /locus_tag="PK063_12040"
     CDS             7400..8029
                     /locus_tag="PK063_12040"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97829.1"
                     /translation="MSLALFQPAAAAVSIAAMAEPAEPVPAEDYAFFDLAVEDKFLTS
                     HTKLIVIERMTATHLQPDEPQLPTLAWFAEREWFDGRLPQDLVRDFVGKNQRPSRLDT
                     RFSFGVRYRFMMGEGGGDAEASVPLIPATWLVQEEGGAPDVIDHLAFSRVGLNLRADQ
                     ALLYVANPRPDGTGAGFLLWFVRQQKVWSLHDTEVLWVSRPDQGQSGRR"
     gene            8077..8706
                     /locus_tag="PK063_12045"
     CDS             8077..8706
                     /locus_tag="PK063_12045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HMZ97830.1"
                     /translation="MIRKTFSVPPLGCNCSIIGDPVTKQAIVVDPGGAPERILQEVRA
                     MGLTVVSIVHTHAHFDHFLASGAMKQATGAALCLHPDDLPLWDILEMQCRMFGVPYVP
                     VPQPDYWLKDEERVAVGEMEGVALHTPGHTPGSMCFHFPAAKLLVAGDTLFRGGIGRT
                     DLWGGDFDAIEQSIRERLYTLDADTAVVTGHGAETEIGLERETNSFVRA"
     gene            8824..9339
                     /locus_tag="PK063_12050"
     CDS             8824..9339
                     /locus_tag="PK063_12050"
                     /inference="COORDINATES: protein motif:HMM:NF014618.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional nuclease family protein"
                     /protein_id="HMZ97831.1"
                     /translation="MIATARRWLVCPLMSFLLGFSAADVLVYADEPGSSPQVTISQVR
                     VGLSDHGPVVLLSADGKTIPVFVDHTVAASIQAALTGEKLPRPLSHELMHTILESLGG
                     RVVRTVITLKAGTYYGSLTVAFQGQEKVFDSRSSDSIALAIHFHAPILVARDMLDAVG
                     KSSLEPKPESL"
     gene            9480..9803
                     /locus_tag="PK063_12055"
     CDS             9480..9803
                     /locus_tag="PK063_12055"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ97832.1"
                     /translation="MKNQRKHERVHVQFRSHFSMKGKMLAGDGDLTDLSPGGCRIISP
                     VEVLVGSEVELCIFPGDNANPILIDAATVRWCRPNEFGLSITKIRGPVQRQLTDVWRK
                     LAKPA"
     gene            complement(10054..11043)
                     /gene="trpS"
                     /locus_tag="PK063_12060"
     CDS             complement(10054..11043)
                     /gene="trpS"
                     /locus_tag="PK063_12060"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HMZ97833.1"
                     /translation="MTTTRKRVLSGMQPSGLLHLGNWLGALENWNTLQAQYECYFFVA
                     DWHALSSNYADTSRLREYVRELLIDWLAAGIDPNRATVFVQSQVPDHAILHLLFSMII
                     PVSWLERNPTYKEKQEEIKERDLSTYGFLGYPVLQAADILLYKPDFVPVGKDQLPHLE
                     LTRELARRFNSLYGSVFPEPQEHLTKFPKVLGTDGRKMSKSYGNAINLSDTEAVVRQK
                     LKTMITDPARVRRTDPGNPDVCPVYDFHKIFSPLPVIEQVNQDCRKAAIGCIDCKKLV
                     ADRVVERLAPMWEARANLTQHPGRLDDIAEDGRRRATAVSSQTMAEVREAMKI"
     gene            complement(11098..13095)
                     /locus_tag="PK063_12065"
     CDS             complement(11098..13095)
                     /locus_tag="PK063_12065"
                     /inference="COORDINATES: protein motif:HMM:NF016251.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator"
                     /protein_id="HMZ97834.1"
                     /translation="MVPRSVSRAPHLRACSVALAVALLVGFATLGETAPAPKTPAAPR
                     SNQAKPPANTGQSAIDQAKRLIDAEQPEAAAVMLRRFIEGGPGPDLLDDAYLLMAAAM
                     YGMKEHAETIRYVNQLLGEFPNSDLVDRAKLLLAKTHARAGNLDLALPLLSEVRSLSA
                     DPAIKRDALRLTGEFQVQKKDFLRAIQAWLDELPLDVGDQSRETETQIRELVNDKLDA
                     PTLMRVRDAYPKTFPGDLASIKLIELHTAAGEDHLVERDVRLFLSRFPNHPYAAKAAD
                     LQSVVRTKFKSHAYSIAAIFPMSGKLAPFGTEVLNGIQLALERTKDGGETPSIGLIVK
                     DTESDRAAFLDELSAVLSDDRPLAVIGPLLSKNLPVMAEMAERTHIPLITPSATVPNL
                     RRFGNYVFSTALTYGHQAKRVADYAVKEQQFKRFAILYPDTPYGRDLARLFAQEIRQQ
                     DGEVIVSEAYKEGDTDFRAVIGRLKAEDLKKYGVEVQVDNDPAKTGIRQGAGKKGKRL
                     LYSPGFDAVFIPGRSLDVGLLAAQLAFYDIAVPLLGTNGWNTPDFARVADRSVEGSVF
                     TDGFFTDSTSPIVQEFVERYRKRFQATPSLFAAQGYDAARLAVEAIRRGATSGEAVRD
                     YLMMQHDLPTLSGPSGFNPDGTLNRHVFLIQVKQGKFVPLE"
     gene            13256..14209
                     /gene="xerD"
                     /locus_tag="PK063_12070"
     CDS             13256..14209
                     /gene="xerD"
                     /locus_tag="PK063_12070"
                     /inference="COORDINATES: protein motif:HMM:NF001399.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HMZ97835.1"
                     /translation="MKSRDAASHAPQESDSLPLAPLVARYCDDLRIARGLSRHTLSAY
                     QRDVTEFQRYLRDQQIHDPAQVSPPLLAAFLEHLHRGGLAASSRARALAAVRSLFRFL
                     KQEGVVAANPTVSLRSTSRARHLPKTLSLEEVASLLDLPHRGAPEDHRDRAMVEVLYA
                     AGLRVSELIALRMDQCNLEVGYVGITGKGDKQRVVPIGRPAVAEVQAYVMSARPMLLK
                     HRSSRFLFVTRRGTPLTRQAFWKLLRARAQRAGIARMPSPHMLRHSFATHLLQRGADL
                     RSVQAMLGHADIATTQIYTHVDAAQLKKIHTACFPRHKSRR"
     gene            14353..14428
                     /locus_tag="PK063_12075"
     tRNA            14353..14428
                     /locus_tag="PK063_12075"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14386..14388,aa:Val,seq:tac)
     gene            14562..14639
                     /locus_tag="PK063_12080"
     tRNA            14562..14639
                     /locus_tag="PK063_12080"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14597..14599,aa:Asp,seq:gtc)
     gene            14712..15428
                     /locus_tag="PK063_12085"
     CDS             14712..15428
                     /locus_tag="PK063_12085"
                     /inference="COORDINATES: protein motif:HMM:NF013760.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HMZ97836.1"
                     /translation="MFQSGVMGLVGSLGAVSKIVLLLLLVASILSWGVILYKWRTFKA
                     ADREDQRFFNAFTKIRDLDELYRQSKRAEGSPSARVFQGIMDRVVTASGDGAVSPSLA
                     AAGSKESAAAFDHQYMDKTVSYLVQNQVSHLEAYLPVLATTGNITPFIGLLGTVLGII
                     DSFREIGMQGTASIAAVAPGVSEALVATAAGLFTAIPAVIFYNYYLTRIRKTVFRIES
                     FTVEAMRSLQTRLKQPQAGV"
     gene            15431..15883
                     /locus_tag="PK063_12090"
     CDS             15431..15883
                     /locus_tag="PK063_12090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biopolymer transporter ExbD"
                     /protein_id="HMZ97837.1"
                     /translation="MTSETRHRRFMAEINVIPLVDVVLVLLVIFMVTAPMLYRGMDIN
                     LPKSASNTIKPEARAVLSIERDQRLYLDKDAVSVVQLERKLRALKDQSPDVSLYLRAD
                     RDVPYGIVVQVMDSVKKAGIEKLGMVTEPTGAERVNESVATPSQPRKK"
     gene            15976..17166
                     /locus_tag="PK063_12095"
     CDS             15976..17166
                     /locus_tag="PK063_12095"
                     /inference="COORDINATES: protein motif:HMM:NF024503.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015291 - secondary active transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB family protein"
                     /protein_id="HMZ97838.1"
                     /translation="MGEAGGDRFRKTVVVSLLLHLCLLSIIMGAKFFKKTERPLSAVE
                     VSLVTLPPVEAKPEPQVEKVEKAVPKPAPKPVQSAPIPVPPKPVQAPTPTPPPVQSAP
                     VAKPAPPAPAPAPAPVPVPKLEAPVLTAPQPIPQAAKSPSSAPVTNRADVLRDVMKDV
                     ELPLNAPKYGDIAPMKPAEVKKSAQAKLGAPERSDLDAMLKKLNVPDMAAPQVAVPQE
                     PPKPNVTPAKRASLSEEMTSDLDRELQDLKKLQAPPPVKATEPVREVKPMFREPQPPV
                     TAPPVAASVTRSKPTPMLRVPGMSGSNPYLARVQARISGFWTAPPVDISGKALTVTVR
                     FRLERDGRVGSVIIEQSSGNDYYDMAAQRAVQSAIPLPPFPPDLTDSYFDAHFTFAVG
                     EAAG"
     gene            17163..18494
                     /gene="tolB"
                     /locus_tag="PK063_12100"
     CDS             17163..18494
                     /gene="tolB"
                     /locus_tag="PK063_12100"
                     /inference="COORDINATES: protein motif:HMM:TIGR02800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system beta propeller repeat protein
                     TolB"
                     /protein_id="HMZ97839.1"
                     /translation="MNRVIIGLMLTLCVVVGAGLFGILDSRATDVFLEATRPDFQKIP
                     IGVFGFQNGGGPEWLGGRLEEVLKADLQRSLVFSLVDLPGIGVKAREVSTTDKAVFKQ
                     AAENGVSVLVWGKSGQKNGSKDSELLMDGFVYDSGSDEVVGGKRYVGSTSVVRLMAHR
                     FADELVFRYTGEPGIARTKIVYVAEHGNARELFVMDYDGYEPKQITADGFLNLMPRWS
                     PDRRFIVFTAYRSRNTQDIDILELATGKRWTLVSMPGLNITPALSPDGNYLAFASSQD
                     GNSEIYKLDTRTKTPQRLTVNQGGDLSPTWSPTGREIAFTSDRGGAPQVFVMSADGSN
                     VRRLTYEGDYNAAPAWSPRGNWIAYVCRTAQRLYKLCIVSPDGQKRVQVTTGPGIDDS
                     PSWSPDGRHLTFSSTVDGKSHIYMVDTDGKNLERITFGGTHNSSPSWSPAL"
     gene            18562..19311
                     /locus_tag="PK063_12105"
     CDS             18562..19311
                     /locus_tag="PK063_12105"
                     /inference="COORDINATES: protein motif:HMM:NF012894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HMZ97840.1"
                     /translation="MRIRVATMGLTMVVGMLLVMQGGCSKKSIQSGGDAQSSDRGMAK
                     SGAPAQSQAQLPPPTGLDAPSATFPDLSLSSKPEDPETGGLRGFDSVSGGKAPSEERL
                     GGGGTMLAKVEPSESTARQIEEIRREQAKEQAASAEAGLRDVFFGYDSWTITEDGRQS
                     LTQDAQWIKANAGALVKIEGHCDERGTLAYNLVLGEKRAKAVRNYLVELGVGANRLSV
                     VSYGKERPFCNERSESCYQQNRRGHVVVRSK"
     gene            19377..21053
                     /gene="ybgF"
                     /locus_tag="PK063_12110"
     CDS             19377..21053
                     /gene="ybgF"
                     /locus_tag="PK063_12110"
                     /inference="COORDINATES: protein motif:HMM:NF024915.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system protein YbgF"
                     /protein_id="HMZ97841.1"
                     /translation="MDSEWPYRKTMTDQPSNAKRVTPGTYAQAARFGACVVVVTGCVL
                     LSGCVAQQADLKQTERELQRRIKQQTEEQAQNRARQNQEIVSLREQDIPSLRGDVDKA
                     LHRAQSLDARQDDLLAKVASQESKFERRIGEAEKRSAEEGKRLGWVEKQLVDQDAMLK
                     GERDRNRAELAAVTARLDQINSHIEAIQKNVLDAMQKTTTGLAQKVDSRLDEQQKLLH
                     GLETRSQNVAQLDAQNKVLGDQVGKFNQALVDFKQALGSLGERVVQQDQTVKHLAATL
                     EQDTVALSKRTDALAGKMDADNKVTADHFNEVNRSVASVAKALENAGGKFVSREDDHE
                     RRLDDTTRELTHVQAQIQTLDKNLENQHAFLKQVEQHLVALRANATQRSEPAPAVAEA
                     APLPQAIPAPVPPPAPAQTQDFASSSAITPRAENRSAALVADRESYERTLTRFKDGDL
                     DGARQGFAEFLVQHPHSDLAPNARFWLGESYYGKKDYSRAIDAYDQVQLNHPASEKVP
                     AALLKKGYAYLALKDRKKAASALKQVIDLYPRSPEANKAMDKLNQLKESH"
     gene            21056..21835
                     /gene="ybgF"
                     /locus_tag="PK063_12115"
     CDS             21056..21835
                     /gene="ybgF"
                     /locus_tag="PK063_12115"
                     /inference="COORDINATES: protein motif:HMM:TIGR02795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system protein YbgF"
                     /protein_id="HMZ97842.1"
                     /translation="MKLRFAGALRVSAMLACGLVVAGCAKHADFLEIRDQVSIMARTQ
                     DQEQKRFEAMQRRLESLERVREPEGGKLRLDDAMTRLQKLEGRLAKVEEAQLAQAAAI
                     RSDAALAEASRQARISKPSGPIEPQAIVPGVPSITPTSAFNLAYNDYLNGKFDLAVNG
                     FQHFIKDFPSTSLTPNAHYWLGESYYGQKDYIRAIQSFEHVVNEYAGNEKVPAALFKL
                     GLSAAETGDTAKSRKYLKRVIEEYSTSDEAKLAKTKMAEIR"
     gene            21908..23704
                     /gene="mutL"
                     /locus_tag="PK063_12120"
     CDS             21908..23704
                     /gene="mutL"
                     /locus_tag="PK063_12120"
                     /inference="COORDINATES: protein motif:HMM:TIGR00585.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HMZ97843.1"
                     /translation="MDIASSVGKIQVLPSDVIGRIAAGEVVERPAAVVKELLENSLDA
                     GSSAITVEIKDGGLGLIRVSDDGEGMSRRDASLAFERHATSKLQSDDQLGAVRTMGFR
                     GEALPSIAAVSKVRLTTVARHDQVGTQLWLTGGTLTRVEDAAAIPGTTIEVSELFFNT
                     PARRKFLKSTTTEFSHISHVVQQAALAWPQVYMRLVHNGYEVFALPAVSSPRDRVLQV
                     YRAAFGERALAVDVERDGLLLKGFIIDPVRARAGRTPQELFVNRRPIKNSTVQHAVID
                     GYSSFLAKGHAPLFVLFLDVEPHRVDVNVHPTKREVRFADTEQIHQLVRSAVRQTLGR
                     AQVEASMAGAAHAEMTGVIPPTLSFPERERMSFGEAPPGPMARSKASVTPPDSAESQT
                     SFVGEGATAYASPASTDIVALGQMNRTYLIAQVGNELQVVDQHTAHERVLFERLWRAW
                     QGRAVTSQPLLLPEPLELPVQQAVILQRHLPELERLGLLIEPFGPSSFLIRSLPIMLG
                     HPDLSALVQDLIDDLEQWDSISSLETKVKPILASLACHAAVRAGRSMALPEITQLVQD
                     WVAEGLIMTCPHGRRVAFRLSGDELARLFDRA"
     gene            23724..24752
                     /gene="miaA"
                     /locus_tag="PK063_12125"
     CDS             23724..24752
                     /gene="miaA"
                     /locus_tag="PK063_12125"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HMZ97844.1"
                     /translation="MIRLTESVLASRPLVVLVGPTAVGKSDVGLRLARALDTDLLTAD
                     SRQVYRGMDIATDKPAVAQQQGVPHRLIDLVDPDESFNAGQYRQLALQEIERLYGERR
                     LPLIVGGTGLYVRTLIHGLCDAPRADQAFRDSLLQKAQGQGRFFLHAELAQVDPELAA
                     RLHPHDEVKIVRALEVFHLSGRRLSDVQQEHRFAEQPFSVLMIGLNRDRAELYRRIDE
                     RVEAMFARGVVEETAALLAKGYGRETGAMKGLGYQQVAGYLSGDYDRAEALRLLKRDT
                     RHFAKRQLTWFRKEPGLQWWMLTEQDTAEDVAGRLLETIHTFVQTLNDERQPHRPAPR
                     TIEMESTS"
     gene            24749..25648
                     /gene="mtnP"
                     /locus_tag="PK063_12130"
     CDS             24749..25648
                     /gene="mtnP"
                     /locus_tag="PK063_12130"
                     /EC_number="2.4.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017061 - S-methyl-5-thioadenosine
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-methyl-5'-thioadenosine phosphorylase"
                     /protein_id="HMZ97845.1"
                     /translation="MKKAKKTIQPAVGIIGGSGLYQVEGLEQVREVRLRTPFGAPSDA
                     IVVGVLGGMGVAFLSRHGRGHRINPSSINYRANIYALKSLGVTQVISISAVGSMKESI
                     EPGHVVLPDQFIDLTKRRISTFFDEGIVAHVGFSEPVCSSLADTLEEAGRSAGATLHR
                     GGTYVCMEGPQFSTKAESRLYRQWGVDVIGMTNMPEAKLAREAELCYATMALATDYDC
                     WHETEEAVTVGAILATLHRNVALAKEILKTAVPKLDPDRACACRQALATALITAPDKM
                     SASAKRRLNLLIAPYVRTRKGKR"
     gene            25652..26569
                     /locus_tag="PK063_12135"
     CDS             25652..26569
                     /locus_tag="PK063_12135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="HMZ97846.1"
                     /translation="MGKLLVVGSVALDTVKTPFGEVAEVLGGSATYFSTAASYFTSVD
                     LIAVVGDDFPEQHVAFLKSRKIDLAGLERRPGATFRWKGAYSHQLNEAQTLDTKLNVF
                     ETFRPKIPAQYSSPDVLFLGNIDPNLQLDVLQQVKRPALVACDTMNFWINGKRDALWN
                     VLQHIDILIINDGEARALGEDTNLVKVAKKILARGPKHLIVKRGEYGVLMFNDKQVFG
                     APAFPLDDVRDPTGAGDTFAGGFLGYLAATGNRSPEAMRQAIIFGSVMASFTVEAFSL
                     DRLRILDYKEIEARFKEFKRLTHFEDIGA"
     gene            26566..27264
                     /locus_tag="PK063_12140"
     CDS             26566..27264
                     /locus_tag="PK063_12140"
                     /inference="COORDINATES: protein motif:HMM:NF025912.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ97847.1"
                     /translation="MIVVDRQETRSCRASGMVGSSCLVFLLGLSVLGGCANEENLRKS
                     KGFYQEGVARLSSDQQQAYVSFQKAVKLNPDNKEAHYGLGHIYASQGRLKLAEESFRE
                     AIRIDGDYAEANTYLGQVLASQDRWKDAIAAYRQALSNPLYPTPDLARFQLGKALMHE
                     GDLQGAMEVLEDATTVTPPNVPPAMLQLELARVYHKLGFDARAREALSKVSTLDKGGE
                     QAAAAQELLGKLKP"
     gene            27274..28221
                     /locus_tag="PK063_12145"
     CDS             27274..28221
                     /locus_tag="PK063_12145"
                     /inference="COORDINATES: protein motif:HMM:NF024855.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4115 domain-containing protein"
                     /protein_id="HMZ97848.1"
                     /translation="MESVGEFFRQVRETKGLTVDEVASKTRIRTDFVKALEEGNFAKL
                     PDQVFARGFVRSYARSLGLDEEDAIHRFVQSAGAFYEKQGERERLRQRQVEEERRRRA
                     NRKAVGVAIAVAIATLVFLLSREQTSTLVRRSGPDAPTVSKKVAPFAKDAKEAGSRPA
                     AELPPPIAPPLKPAEPAVVPAKPAQDKPAPVAQAPAPVAVAKAPLPSDTVVTQPSASM
                     GSDGPLAGLSVDGPVGSDGPLVLDLAATELSWVVVQVDSGSHQEALLRPGEKAQWKAQ
                     DQFTVTLGNAGGVRAELNGKPQKPFGPSGKVVRDVVIKR"
BASE COUNT         5653 a         7905 c         8977 g         6150 t
ORIGIN      
        1 gcttgctgcg gtacggcatc cctgatttca agatggagaa gtgggtcatc gaccgtcggc
       61 tggagcagat gaaagccgaa ggggtggagt tcaaaaccgg cgtcactgtg ggcaaagatg
      121 ttaccggcga acagctacgg caggagttcg atgcggtggg gctgacgatg ggcgcggaaa
      181 tggcgcgaga tctgccggtg ccggggcgtg aactcaaggg catccatttc gccatggagt
      241 atctcacgca gcagaacaag cggacggcag ggatctccgt atccgaagaa ccgatcaccg
      301 ccaagggaaa gcgggtggtc atcatcggcg gcggcgatac cgggtccgac tgtttgggaa
      361 cggcccatcg gcagggctgc agcgaagcgc atcagttcga agtattgccc gagccacctc
      421 cgtcccgatc gagctcgacg ccctggccgc tctggccgat gcagcttcgt acgtcccatg
      481 ctcacgaaga aggctgtgat cgtcaatgga gcgtgtctac cacgaagttc accggtcaca
      541 acggacatgt gaccaaactg catgccaacc gggtgaagtt cgagggcggt aagttcgtgg
      601 cgattccgaa tacggacttc gagttggatg cggatctcgt gctcctcgcc atgggcttca
      661 cggggccggt cagaaacggt tttctcgaca gccttggcgt gaattatgat gcgcgtggct
      721 gcgtgaccgt caacgagaac ttcatgacca acctcgacgg cgtctttgcc ggcggcgata
      781 ccaagcgcgg cgcgtccctc atcgtctggg ccatcgccga agggcgcaag atggcggcgg
      841 ggatcaatca gtatctgcaa gcgaacaagt ctgccaagtc aggccgctga aaaagcctcc
      901 cggcgtcgtt ctcgcttccc tcaaaccctc aacgtaccga aacagtacgc ctcgcgggct
      961 ttcgctcgct gcggcctagc tgtataggct tttggagcgg ccccgggccg attctaatgt
     1021 ccttgggcgg tgccccgctc cagtctgtct tatttttgcc ccgcctttta ggatcgctgg
     1081 tatttgtttg tctatcccct tgaatggtgc tgcgccggct ttcgaaccta tgtttcatgt
     1141 cttgggctac aatcgattat gaatctgcct aatgttaccg tgcgcgattc gcgcctccgt
     1201 acagtgccgg ggctaacatg acgaaattcg ctcgtgttcc agacgcagac tgggtactag
     1261 ctggaaatgt cggaagtgca agaatcagcc gcctcagaca agccgaaaat ttcgatgcgg
     1321 tcgtgtcaag gatcatacgt ggcgcccggg tcgaacgctt gaggcgagag cgttcgcatg
     1381 aagatcattc ggctttccgc ttgatcgtgg atcttcgcgt gaaggcccaa agtcttgacc
     1441 agtttttcaa ttctcctgtt ggctaccgcg cgcagtactt cgcgaactgc aaacttggcg
     1501 agagagcaaa tcggttcgtc atcaacgagt tgttttcgaa ggttcttgtg gcaggaaaga
     1561 gagggagacg cctaaaggaa gattttattc gactgtccct taagcattcc tctttcaaag
     1621 ttttgctgca tcaaggccag tggcttcggc atgcgaaacg cgaagatcga gtccttcttg
     1681 ttcccaggtg gcaggccgag tgcgtctcgg gggacaaatt acgacggaaa cttgctcgat
     1741 ggggatcgct ggctccagcg cacgaaacgc gacttctgct gaagggaggc ttcgtaaggg
     1801 cgaccagcag agtaactatc gataagtctc caatgactcg atctagagag cttcacgagc
     1861 ttggatttac ctagagaggc aggaggtatg agtgagaagg aaagctagaa ttgactgaag
     1921 cagtgcaatc aaagggtcgc agctgaacag agtccagaac gccttccatc gatcgtgaaa
     1981 attggaagca gcaacgtttt gccagcgctc atcggccctc ctagacttct ctcgtcctcg
     2041 cctgtatctt ctcgggaatt acattcagga gaatttacaa tgactcagca aacctatccc
     2101 cgtagcccca aagtcctcct cggcggcatc gcccacctgg gccggttcat cgataaagtc
     2161 cgcttgcgcc acgccggcaa gattcaggac tacaactaca tcaccgtcgg gttcgataag
     2221 tatctgatcg attttttaca gatcgatgcg aaggccttcg agcagcaggt gttggcgggc
     2281 gagagcgatg agaagttgtt gagttgggtg aagacccacg gccggaaaca ttccgaggaa
     2341 gaaatcgcgc aatggtcgaa aggtcttctg gcgggcggcc cgaaggacga tgcggcgaag
     2401 cagcgattcc agggacgggt gcaggacatc gccaccaagc gaggcgttcc gctgacctca
     2461 ttgccgcctg tgacgacgtg ggctgatgta atcgagctgg acgaagaacg gatgtagcct
     2521 tacgacagtg aatcgtgggc gatgactatc gtacttcggt ccagcccgtg gattgcgact
     2581 tgaagatcac ggtgcgtgat gaggtgcgga cgaccatgcc gttctgactg ccatcgaccg
     2641 acagcacccg ttcattcggg gtccagtcaa tgttgaagaa gcctcccgta taggtcgaaa
     2701 atcccagtgc ccgctcattg gtgatggcga cggcgacgtg cccttggccg cgaagctgtg
     2761 agacggtctc attcggtccc agcgaaatgg ttgtccagtg cccgcgcgtt tcctggaacc
     2821 caaatacttg ctggttgctg tgcgccagaa tcagaaacgg cagtagttga tgccgtccga
     2881 tccgttcttc tactccaatc gacacttccc gccattgccg caggccggca gaaaacccta
     2941 acaacctgct cgaggtctgg acgaatccgg tgtgtccgcg tgctgcggaa ctgatgaccg
     3001 tttcattcgg ctgtaaggat tcttcaacgc cgccccctgc agctgaccag gcaatgactt
     3061 tgctgtcggt tggtgtgatg gtgacctggc tgcctccgcc ttgagcgtgc gaaggctcgg
     3121 cggtcacgag tagacttgcg gttgaagtgg ttatgacgaa cagcaatagg gcgatagatc
     3181 gatgcaacag gctggctccc attcgatgcg ttaccctaac acatcgtcag gcataagcga
     3241 agattggact tgtgcgggga cgtgcgtgag gtcagcggtg cagaggaaaa tgaaggaaag
     3301 gcgggaccgt gcaaccttgt cacgggtccc gccagctgcg gtcattactt atgctttcgg
     3361 tttgacgttg agcacgacaa tatccagcac gatgtgtttt cccgccaggg gatgattgaa
     3421 gtcgacgaca gccgactcat ccgataggga tacgacggta aatggccgac cttcagcagt
     3481 cgtagccata tccccgcggg caatggtgtg cggcaattgg gcgcgcggaa cggtcatctt
     3541 ttttccggcg tcatattgtc cgaaggcatg gtctgcatca agttcaacgc gcttggtatc
     3601 gcccgaatgc aaacctacaa gggcctcttc caaccctgga aggagttgct tctccccatg
     3661 ggtgtattca ctggtttggg gagggatcat cacatgatcg ttgggcaggg tgatggtcat
     3721 ttgcagtgtc acttttgaac cgtcttcgat ggttggggag cctgtttggg catgcagagg
     3781 acggctcagc aggacgatag cacacaggat cagcaagccg gccaatgata cgcgtgtcat
     3841 agatacctca tctgttgtta gggatagaat acaaggtgat caactgacga ttccgttacg
     3901 gtgagtcaat cttcacaatt ttggtcacac ggttgtcgaa gtcaatttcc aggctacacg
     3961 tgtcgccttt gtgtagaccg ctgagcatgt cagcggaaag ggcggccaga gtccagactt
     4021 ccccttcggc ggttttgaat gtcaggctct ggctcgcttg gtcgacggat tcaaccttca
     4081 cgcgcgtgta cgtcaatgaa gcctggctct ctaggggagc aacaatcggc atggcgagga
     4141 cacatactag actgccgatc acgatgatcg atttcatgat gtcatcctcc ttgtgacaaa
     4201 ggcaggcgaa caatgactca ccgctttcaa accgcgggcc tgaattgcta ctcaatgcat
     4261 atggcaggga gttatcatgt tttcgctggg taacgtcgcg gaaggttgac gagtgcggac
     4321 gaaccggcgc gcaagttgtc cctgcgggac atattgtcct ctcctcggac catggaaaag
     4381 cagcgcaaat gtcgcaggat gatgcatcct tcccaggttc ggaatcgggc ggaataactg
     4441 tcgcactcgc cttgtctgcg atcgtgacgc ttccattgat gggcccatgg ctcagcggtc
     4501 aatcgcttcg accctatctg gagtttccgc cgctcagcac gggtgtcgtg acgcaggtcg
     4561 cattttcctg gccggttttt gtcggtctgt ccgcgctgat tgtctgcctg cttgcgccgt
     4621 ttattgtgcg cgtggcacga acgaacagca ggggtgtatc gacggtagct gggcaagagc
     4681 gcacgccgta tggctccgtt cgccggcagt gtgttttgcc ccatgctttt ccctggtggg
     4741 gttggggtgc tgtcgcttgg accatctgtg catggttcct ggcctggacc cgcttcgagt
     4801 ggatgcagcc gtggcagccc cataccttca ctccgctgtg gctgggctac attgtcgtgg
     4861 tcaatgcctt gacgtatcgc agcaccggcc ggtgcatgtt gatccatcgt ccacggtatc
     4921 tgctctcact cttcccgctc agtgcctgct tctggtggct ctttgagtat ctcaatcgat
     4981 ttgtgcagaa ctggtactac gtaggtggcg gaacgttgac gacaggggag tacctggttc
     5041 gcgcgaccct cccgtttgcg acggtattgc cggccgtcct cagcacggcg gagtggctca
     5101 cggcttgccc gcgcctctcg gcgggattgg accatgttgt cacgatcaat ttcagtcgcc
     5161 gggtatgggg atggttgctg ctatccggcg ctgctgccgg tctgctcggc atcggtctgt
     5221 ggccggacta tctgtttccg ctggtgtggg tggcgccgct cctggtgatc acggcgctgc
     5281 aactgattcg caacgagccg acgatcttca gcgagacggc gcatggtgat tggcgaacac
     5341 tctgggcggt ggcgctggca gcgttagtct gcgggtggtt ctgggagatg tggaatttct
     5401 acagcctggc ccattggcaa tatgccgtac cctttgtgca gggagtgacc ctgttccaca
     5461 tgccgttgct tgggtatgcc ggttatctgc cgttcggcct ggagtgttgg gccgtggccg
     5521 acttgtgtct cgccaggaag tttgcaggag gcgtggccta ttatcgtgcg gctgaaccgg
     5581 agacggattt cgcgcaacgg aaccccacgg tagcagaacg ctgatcggca ggtgcgccgc
     5641 tgcgagttgc cgttcgcagc atgatcgggc ggcttttcca ggaaccaccg cgaaggcttt
     5701 tgtatcggcc gctggtcggg ccgggaggat tacgctccgg catgtaggca taatagtcga
     5761 aaccgaacca gtcattgacc cattcagcga cgttgcctgc catgtgatgc acgccatagt
     5821 agcttttgcc cggttcgccg ctgctcaccg gcgccagaat cggaatctcg tgcacatgat
     5881 gctgcccgaa catagccagg gaattgtcgg ggagcgactc gccccaggga aaacgattcc
     5941 cgtccggccc ccgcgccgcc ttttcccatt cggcttccgt cggcagccgt ttgcctgagg
     6001 cacggcagag gttgtcggct tccttccacg tgacatacag ggcaggccac tgcgccaagg
     6061 tctcatcgct gaccgagtgc acggtgatga cgtgccagat caaatgctgg agatctttgg
     6121 acgggtggat ctttcgctga tgcagatagg tcagatattc cccgaggctg acttcatcac
     6181 gatcgatctc gtaggcatcc aaccagacgc gatgctgcgg gagctccgta tcgtcgaact
     6241 gtgtgcccat gccatagggg tcgtcgtcca ctcgaatgct gccgagtaag aacggtccct
     6301 caggaatgag aacggccggt gagctggccg ctaattccgc aatcgacgtc aggtgtttgg
     6361 ccagctccgc tgttggcgga ggggtcgggg cgcgagcggc gatggagagc gccggattga
     6421 gccatgtggc cgcaacgctc aggatcacga gactgagcgc atgcaggagt gaggcgattc
     6481 ctgggaacaa cgtgcgaggg atcattacaa cttactcggc gaggcgacgg cttttccgat
     6541 ttcggcaatg agccgccgtt cgatctccgc gatctcctca gcatccaccg ccaggacgcg
     6601 cccgccttgg gctacccgtt caaactcggc ttttacgctc aaccgggtga cgttcgaggg
     6661 gagggcttga agggatacca catactgatt gcgggagccg gccgtttcca ccgaggttgg
     6721 gatggaaatt tttcgctcgg tgacgaagac cgctttttga tcggttttga ctgtgacgcg
     6781 tatccggtac ccgtttcgcg tcagggcttc ttccgcagct ttagcaacgg ccggcagcgg
     6841 acgcgggaga tcctcgacct gcgagccttt ttcttccacc cggatactgt ccgtcgcctg
     6901 ggcggctttg gcggcggtcc gttgaatctc tccggagagt tttttcgatt cggccagttg
     6961 cgcatcgagc ttcgtgccga gcgtcttcgc ttcggtttgc agcgacttgg cctcagcctg
     7021 ggcatgctcc gtctgcttct tcgcgtcccg gagttcctgg ttgagcagat cgatctgctg
     7081 ctgcatgact ttgttaccgt cctgcagcga attcagcagc gattcctgct tcgccagttg
     7141 cttccggaga ttttcgtttt cctgccggaa tggagattcg tcgggggtac acccgacaca
     7201 ccacgatagt accgcgaggc tgaagagggg ggcgagcgat cgctgggagg ccttgatcat
     7261 agtttgggta agacaatcag actagtatca gagttgagcc ccccttgtct atcttcaatc
     7321 actttctcgc cggtttgacc atgggaaatg gagcggctat tctgtgctca tgcggtactg
     7381 gtacgaggcg gttttcctca tgagtctggc attgtttcag ccggccgcgg cggcggtttc
     7441 gatcgcagcg atggctgaac cggcggagcc cgtgcctgcc gaggactatg cgttttttga
     7501 cctcgcggtc gaggacaagt ttctgacgtc ccacacgaag ttgatcgtca tcgaacggat
     7561 gacggcgacg catctccagc cggatgagcc gcagctgccg accctcgcct ggtttgccga
     7621 gcgcgaatgg ttcgatggcc gtttgcccca ggacctggtg cgggatttcg tgggcaagaa
     7681 tcagcggccg tcgcggcttg atacacgatt tagtttcggc gtgcgctacc ggtttatgat
     7741 gggcgaagga ggcggcgatg ccgaagcctc tgtgcctctg attcccgcca cctggttagt
     7801 tcaagaagaa ggcggcgccc ccgacgtcat cgaccatctg gcattttcgc gggtgggtct
     7861 gaacctgcga gccgatcagg cgttgctgta tgtcgcgaat ccgcgtcccg atgggaccgg
     7921 tgcgggcttt ttgctgtggt ttgtgcggca acagaaggtc tggtccttgc acgacacaga
     7981 agtgttgtgg gtttcacggc cggaccaagg tcaatcaggc cgccggtagg atgactgaga
     8041 cgttcaggtt cctgttcgat tcactgagga gtgcgcatga ttcgtaagac gttttctgtt
     8101 ccaccactcg ggtgtaactg ctcgatcatc ggggaccccg tcaccaagca ggccatcgtg
     8161 gttgatccgg gcggcgcgcc tgagcgcatc ctgcaagaag tgcgtgcgat gggattgacg
     8221 gtggtgagta ttgtccatac gcatgcacac ttcgatcatt ttctcgcgtc cggcgccatg
     8281 aagcaggcga ccggtgcggc gttgtgtctg catcctgacg acctgccgct ctgggacatt
     8341 ttggagatgc aatgccgcat gttcggcgtg ccctatgttc cggtgccgca gccggattat
     8401 tggctgaaag atgaggagcg tgtggccgtc ggcgagatgg aaggcgtggc cttgcacacg
     8461 ccgggacaca cgcctggatc catgtgtttt cactttcccg ctgcaaaatt gttggtggcg
     8521 ggggatacgc tgtttcgcgg tggcatcggc cgcaccgatt tgtggggcgg ggatttcgat
     8581 gccatcgagc aatcgatccg ggaacggctc tacacgctcg atgcggacac ggccgtcgta
     8641 accggacatg gggctgagac cgagatcggc cttgagcgag agacgaattc attcgtgcgc
     8701 gcctagcgga gaggtgggca tttcacggtg cgtgaacctt ctgcggggcg cgagatcgtt
     8761 ccccgacagc ctttgtcata gccgctcatg aacgggcctc catcggaaac acaggagggt
     8821 attatgatcg cgacggctcg gcgctggttg gtatgtccgc tgatgtcctt cctgctggga
     8881 ttctccgctg ccgatgtgct cgtgtatgcc gacgaacctg ggtcttctcc ccaggtcacg
     8941 atcagtcagg tccgggtggg attgtccgat cacggcccgg tggtgttgct atcagccgac
     9001 gggaaaacca ttcccgtctt tgtcgaccac accgtcgccg cgtccattca ggccgcactc
     9061 accggtgaaa agcttccgcg cccgctttcc cacgagctga tgcatacgat tttagaatcg
     9121 ctcggcggac gggtggtccg gacggtgatt acgctcaagg cgggcaccta ttacggaagc
     9181 ctgaccgtgg cgtttcaggg gcaggaaaag gtgttcgata gtcgttcttc ggactccatc
     9241 gccctggcga ttcattttca cgcgccgatt ctggtggcgc gggacatgct ggatgcggtg
     9301 ggcaagtcct cgctggagcc gaagcccgaa tcactctgag ctcgcgcccg acggaacatc
     9361 gcgggactct cgcgagtcgc gtagaagtat acagtgctgg ccttttgtcc ggttctatcc
     9421 tatcgtactg ctgatgcgca gaggcctgag gttgtcacag gtacggaggc cacgtttcca
     9481 tgaaaaacca acgcaagcat gagcgggtgc acgtccagtt tcgcagtcat ttttcgatga
     9541 aaggcaagat gctggccggt gatggagatc tcaccgatct ctctccgggc ggctgccgga
     9601 ttatcagccc tgtcgaagtg ctggtcgggt cggaagtgga gctctgtatt ttccccggtg
     9661 acaatgccaa tcccatcctc atcgatgcgg ccaccgtacg gtggtgccga cccaacgagt
     9721 tcgggttgtc gatcaccaag attcgagggc cggtccagcg ccaattgacc gacgtgtggc
     9781 gcaagttggc gaagcctgct tagcaggctg ttgatacagg cgcgccagcg gcgttctcac
     9841 ctcgctcaga ggctcaccgt acggcgcgag tacgattcgc ctcttcgctc gcttcggcct
     9901 tgctgcacgg cctttctgaa cagcctgcac ggcgccagac gcaactgcgc atttcacgca
     9961 acgatcctct tccggatgcc gcgtacagtt gatcaacgcg ctgctagtcg agtgttattc
    10021 cagaagtgag ttgcccaaat cggataggcg tggctagatc ttcatggcct cccgcacttc
    10081 ggccatcgtc tgagaagaga cggcggtcgc gcggcgtcgc ccgtcctctg caatgtcatc
    10141 aaggcgcccc ggatgttgcg tgaggttcgc acgagcctcc cacatcggag ccaggcgctc
    10201 caccacgcga tcggccacca gcttcttgca atcgatgcag ccgatggcgg ctttccggca
    10261 atcctgattc acctgttcga tcaccggcag cggcgaaaaa atcttgtgaa agtcgtagac
    10321 ggggcagacg tcgggattcc cggggtcggt gcgccggacg cgcgcgggat cggtgatcat
    10381 ggtcttgagc ttctggcgga ccaccgcttc cgtatcggag aggttgatgg cgttgccgta
    10441 gctcttgctc atcttgcgtc catcggtgcc gaggactttg gggaatttcg tgaggtgctc
    10501 ctgcggttcg ggaaagacgg agccgtaaag gctattgaag cggcgcgcca gttcgcgcgt
    10561 cagttcgaga tggggcaatt gatctttgcc gaccggtacg aaatccggct tgtagagaag
    10621 aatgtccgct gcctggagga ccggatagcc gagaaacccg taggtgctga ggtcgcgctc
    10681 cttgatctct tcctgcttct ccttgtaggt cggattccgc tccagccagg acaccggaat
    10741 gatcatggag aacagtagat gaaggatggc atggtccggc acctgtgact gcacgaatac
    10801 ggtggcccgg ttcgggtcga tgccggctgc cagccagtcg atgagcagct cccgcacata
    10861 ttcgcggagc cggctggtgt cggcgtagtt ggacgacaac gcatgccagt ccgccacgaa
    10921 aaagtaacac tcgtattgag cctggagcgt gttccagttt tccagcgccc ccaaccagtt
    10981 accgagatgg agcagcccgc tcggctgcat cccgctgagc actcgcttac gcgtcgtcgt
    11041 catgccgtca ctcccatatc ccgaaccgat gtcttgctgt ctccccgagc agcagggcta
    11101 ctccaggggg acgaacttgc cttgtttcac ttgaataaga aagacgtgtc gattgagggt
    11161 gccgtcggga ttaaatccgc tggggccgct caaggtcggc aggtcatgtt gcatcatcaa
    11221 atagtcgcgg accgcttctc cgctggttgc gcctcgccgg atcgcttcca cggccagtcg
    11281 cgcggcgtca tagccttggg cggcaaagag tgacggcgtc gcctgaaacc gtttgcgata
    11341 ccgttccacg aattcctgta cgatcgggct ggtgctatcg gtaaaaaatc cgtcggtaaa
    11401 cacgctgccc tcgacactgc gatcggccac gcgcgcgaaa tccggcgtgt tccatccatt
    11461 ggtgccgagc agtggtacgg cgatgtcgta aaaagcaagc tgggccgcca gcaggcccac
    11521 gtctaacgaa cgtcccggaa tgaagaccgc atcgaatccg ggcgagtaga ggaggcgttt
    11581 tcccttcttg cctgcgccct gcctgatccc ggttttggcc ggatcgttgt cgacttgcac
    11641 ctcgacgccg tacttcttca gatcttcggc tttcagcctc ccgatcaccg cgcggaagtc
    11701 ggtgtcgcct tctttgtagg cttcgctgac gatcacttct ccatcctgct gccggatttc
    11761 ttgcgcgaag aggcgtgcca ggtcgcggcc atagggcgta tcgggataga gaatggcaaa
    11821 ccgtttgaac tgctgctctt tgacggcata gtccgccacc cgtttggctt gatgtccgta
    11881 cgtcagtgcg gtgctgaata cgtagttgcc gaagcggcgt aagttcggga cggtcgcgct
    11941 gggggtgatc aagggaatgt gggtgcgttc ggccatttct gccatgaccg gcaggttttt
    12001 cgacagcaac ggcccgatga cggcaagcgg gcggtcgtcc gacaagacag cagacagttc
    12061 gtcgaggaat gccgcgcggt cggattctgt gtccttcacg atgagcccga tcgacggagt
    12121 ttcaccgccg tccttcgttc gctccagcgc gagttgaatc ccgttcaaca cttcggtgcc
    12181 gaagggcgcg agttttccgg acatcgggaa aatggccgca atcgagtacg cgtgcgattt
    12241 aaacttggtc cgcaccacgc tttgcaggtc ggcagccttc gcggcatacg ggtggttggg
    12301 aaagcggctc agaaagaggc gcacgtcccg ctcgactaag tggtcttctc ccgccgccgt
    12361 atgaagttcg atgagcttga tggaggccaa gtctcctggg aaggtcttcg ggtacgcatc
    12421 gcggacgcgc atgagcgtcg gcgcatccag tttgtcattg accaattctc ggatttgagt
    12481 ttccgtctcg cgcgactggt cgccgacatc cagcggcagc tcatcgagcc atgcttgaat
    12541 ggcccgcaga aagtctttct tctgaacctg aaactcgccc gtcagccgca acgcatcgcg
    12601 tttgatggcc ggatcggcgg acaggctgcg cacttcggac agcaggggca gtgcgagatc
    12661 caggttgccg gctcgggcgt gggttttcgc gagcaggagt ttggcccggt caactaaatc
    12721 ggagttcgga aactctccga gtagctggtt gacgtagcga atggtttccg catgttcctt
    12781 catgccgtac atggcggcgg ccatgagcag ataggcgtcg tcgaggagat ccggaccggg
    12841 gccgccttcg atgaatcgtc gcagcatgac ggccgcggcc tccggttgtt cggcgtcgat
    12901 caagcgcttg gcctggtcga tggcggattg tccggtattc gcaggtggct tcgcctgatt
    12961 cgaacggggt gcggccggag tcttgggtgc cggagctgtt tcgccgagcg tggcaaagcc
    13021 tacgaggagc gccaccgcga gggcgacact gcacgcgcgg agatgcgggg cgcgggatac
    13081 tgaacgagga accattgact cctgtgcatg gcgaacgctc tcgccgcaat ggaggctact
    13141 ataggaaaca ggtgctaggg tgtcaaggta agtcgaggcg tttgcgttgt gttcacagag
    13201 aggcttggct atagtcgacg agacatgctt cccgccatca ccgatgaggg cattgttgaa
    13261 gagccgtgat gcggcgagtc acgctccgca ggaatcggat tcgcttccct tggcgccgct
    13321 cgttgcgcgg tattgcgatg atttgcgcat cgcgcgggga ctctcgcggc atacgctctc
    13381 ggcctaccag cgtgatgtga cggagtttca gcgctatctt cgcgatcaac agatccatga
    13441 tcctgctcag gtgtctcctc cattgctcgc ggcctttctc gagcatttgc accgtggtgg
    13501 tcttgcggct tcgtcacgtg cgcgagcctt ggccgcagtg cgtagtttgt ttcgtttcct
    13561 gaagcaggaa ggcgtcgttg ccgcgaatcc gacggtcagt ctgcggagca cctctcgagc
    13621 gcggcatctg ccgaagacat tgagcctgga ggaagtggcc agtttgctgg atctgccgca
    13681 tcgcggcgcg ccggaagatc atcgcgatcg tgcgatggtg gaagtgctgt atgccgcggg
    13741 tctgcgagtg tcggagttga tcgcgttacg catggatcag tgcaaccttg aggtcggcta
    13801 cgtcggcatt accggaaaag gcgacaaaca gcgggtggtc cccatcggca ggcccgcggt
    13861 ggcggaagtg caggcctatg tgatgagtgc gcgacccatg ctgttgaagc accgatcctc
    13921 gcgcttcctg ttcgtgaccc gccgcggcac gccgttgaca cgacaggcct tctggaagct
    13981 gctgcgtgca cgagcccagc gagcgggaat tgcgcgcatg ccgtcgccgc atatgctgcg
    14041 ccattcgttt gccacgcatc tcttgcagcg gggcgccgac ttgcgttctg tgcaggcgat
    14101 gttgggccac gccgacatcg cgacgacgca aatttatacg catgtcgatg cggcacagtt
    14161 gaaaaaaatc cacactgcgt gttttccgcg ccacaaatcc cgccgctgaa tgtccgatgg
    14221 cgcgagccgt cgtgccaaag gggcctgatc tgcgtaggat aaaaatcttg caagaataat
    14281 gcatgattct tggttgacac tgcttggtgg agttgatagc atcccaaaaa tctgccggga
    14341 tcgaggaaaa acgggcggat agctcaattg ggagagcgct gcccttacaa ggcagaggtc
    14401 acaggttcga tccctgttcc gcctaccaat aagaaataca agaaattgtg cgcggggcat
    14461 tgccttatcc attagtagtg atgtacaaga gtacgcgcta ctgtatttag acagtttgat
    14521 tctgaagatc tgaattcttc ttccgccatc ttgggttgcg tggggccgtc gttcagcctg
    14581 gttaggacgc cagattgtca atctggaagt cgcgggttca aatcccgtcg gccccgccat
    14641 tcccccagct tttggtacaa tccatgctac cgttttcatg cgacgccatg tgaagggaaa
    14701 ggtctaggct catgttccag tcaggcgtaa tggggttggt gggctcgctg ggagcggtat
    14761 cgaaaatcgt gctcctgctc ctcttagtcg cctcgattct ttcctggggc gtgattttgt
    14821 acaaatggcg gacgttcaag gcggctgatc gtgaagacca gcggttcttc aatgccttta
    14881 cgaagatccg tgatctggat gagttgtatc ggcagtccaa gcgcgcagag ggcagcccca
    14941 gtgcgcgcgt gttccaggga attatggatc gcgtggtgac ggcctcggga gacggggcgg
    15001 tgagtccgtc gctggccgcg gctggatcga aagaatcggc cgccgccttc gatcaccagt
    15061 acatggataa aacggtgtcg tacctcgtgc agaaccaggt ctctcatttg gaggcctacc
    15121 tgccggtgct ggcgaccacg ggcaacatta cgccgttcat cggcttgctc gggacagtgc
    15181 tgggtatcat cgactcgttt cgtgagatcg gcatgcaggg cacggccagt attgccgccg
    15241 tggctccggg cgtatctgaa gccctggtgg cgacggccgc cggcctgttc accgccatcc
    15301 ctgcagtcat tttctacaac tattatctga cgcgtattcg gaagaccgtg tttcgcatcg
    15361 agtcattcac cgtcgaagcg atgcgttcat tgcagacgcg cttgaagcag ccccaggccg
    15421 gagtgtagtg atgacgtcgg aaacccgcca tcgccggttc atggccgaga tcaatgtgat
    15481 tccgctggtc gacgtggtgt tggtgttgct cgtcattttc atggtgacgg cgccgatgct
    15541 gtatcgcggc atggacatca atcttcccaa gtccgcgagc aatacgatta agcctgaagc
    15601 aagagcggtt ttgtccattg agcgcgacca gcgattgtat ttggataagg acgcggtgag
    15661 tgtcgtgcag ttggagcgaa aactccgggc gctcaaagac cagagcccgg atgtgtcgct
    15721 gtatctgcgt gcagaccggg atgtgccgta tgggatcgtt gtgcaggtca tggatagtgt
    15781 caagaaagcc ggcattgaaa agcttggtat ggtgacggag cccacaggcg ccgagcgggt
    15841 caatgagtcg gttgcgactc cctcgcagcc acgcaagaag tagcggcgcc gcgactcgcg
    15901 cgccatacgg tcgtatcgca agtcatgacg ttccaagccc tgccaagaca taccgcgctg
    15961 tccctaatcg gagatatggg tgaggccgga ggtgaccgtt ttcgaaagac ggtcgtcgtg
    16021 tcgttacttc tgcacctgtg tctcctctcc atcattatgg gggccaagtt ctttaaaaaa
    16081 acagaacgtc cgctttcggc ggtggaagtc tctctcgtga cgttgccgcc tgtggaagcg
    16141 aagcctgaac cgcaagtgga gaaggtggag aaggcggtac cgaagcccgc acccaagccg
    16201 gtgcaatcgg ctccgattcc cgtgcctcct aaaccggtgc aggccccgac gccgactccg
    16261 ccacctgttc aatcggcgcc cgttgcgaag ccggcaccac cggcgccagc acctgcgcct
    16321 gctccggttc ccgttcccaa gctcgaggct ccggtattga cggcacctca accgattccg
    16381 caggcggcca agtcaccttc ttctgccccc gtcacgaatc gggcggatgt gttgcgtgat
    16441 gtcatgaaag atgtggaact cccgctcaat gctccgaaat atggagacat tgcgccgatg
    16501 aagcccgcgg aggtcaagaa atctgcgcag gcgaagctcg gagcgccgga acgctctgat
    16561 ctggacgcca tgttgaagaa gctgaacgtg cctgatatgg ctgcgcctca ggtggcggtt
    16621 ccacaagagc ccccaaagcc gaacgtcacg ccggcaaaac gcgcatcgct gtcggaggaa
    16681 atgacgagcg atctcgatcg tgagcttcag gatttgaaga aactgcaggc gcctccgccc
    16741 gtgaaagcaa cggagccggt gcgagaagtg aagccgatgt tccgcgaacc gcaaccgccg
    16801 gtgaccgcgc cgccggtggc ggccagtgtc acacgcagca agcccactcc catgctgcgg
    16861 gtgccgggca tgtcagggtc gaatccgtat ttggcgaggg ttcaggcacg gatcagcgga
    16921 ttctggacgg cgccgccggt cgatatttca ggcaaggctt tgacggtgac ggtgcggttt
    16981 cggttagagc gggatggtcg ggtcgggtcg gtcattatcg agcaatcttc ggggaacgac
    17041 tattacgaca tggctgcaca acgcgcggtg caaagcgcga ttccgttgcc gccctttccg
    17101 cccgacctga cggattcata tttcgatgct cacttcactt ttgccgtagg cgaggctgca
    17161 ggatgaatcg tgtgatcatc ggtcttatgt tgaccctctg tgtcgtggtg ggcgccggac
    17221 tgttcggaat tctggactcc cgcgccaccg atgtctttct tgaggcgacc cggcctgatt
    17281 tccaaaagat ccccattggt gtgttcgggt ttcagaacgg tggcggcccg gaatggctcg
    17341 gggggcgact cgaagaagtg ttgaaggccg accttcaacg atctcttgtg ttctccctcg
    17401 tggatctgcc cggaatcggt gtgaaggccc gcgaggtgtc gaccaccgat aaggccgtgt
    17461 tcaaacaagc ggctgagaat ggggtctccg tcctggtatg ggggaaatcc ggccagaaga
    17521 acggcagtaa ggacagcgaa ctgctgatgg atggcttcgt gtatgacagc ggcagcgacg
    17581 aggtcgtcgg aggcaagcga tacgtcgggt caacatcggt cgtccggttg atggcccatc
    17641 ggtttgccga cgagttggtg tttcgttata ccggcgagcc agggatcgcc agaaccaaga
    17701 ttgtctatgt cgcggagcat gggaatgccc gtgaattgtt tgtgatggac tacgacgggt
    17761 atgagccgaa gcagatcact gccgacggct ttctgaatct catgccccga tggtcgccgg
    17821 atcgccggtt tattgtcttc acggcctatc ggagtcggaa cacgcaggac atcgatattc
    17881 tggagctcgc gacggggaag cgctggacgc tggtgtcgat gcccgggctg aacatcaccc
    17941 cggccttgtc gccggacgga aattatttgg cctttgccag cagccaggac ggcaattcgg
    18001 agatttataa gctcgatacg cgaaccaaga ctccgcagcg tctgaccgtg aatcagggag
    18061 gcgatttgtc gcccacctgg tctccgaccg gacgggaaat cgcgtttacc tccgatcgcg
    18121 gcggcgcccc gcaagtgttt gtcatgagcg ccgatggctc caacgtccgc cgcttgacgt
    18181 acgaggggga ttacaatgcc gcaccggcct ggtcgccgcg cggcaattgg atcgcctatg
    18241 tctgtcgaac cgcccagcgg ctgtacaaac tgtgcatcgt gtcccctgat ggtcaaaaac
    18301 gggtgcaggt tacgacgggc ccggggatcg acgactcgcc atcctggtct cctgatggcc
    18361 gccacctgac cttcagttca accgttgacg gaaagagcca catctacatg gtggatacgg
    18421 acggaaaaaa tctggaacgc atcacattcg gcggtacaca caatagttca ccgtcatggt
    18481 ctccggcact ttaggattga gtactcaatt gacaggatct acaggcatac taaccattca
    18541 ccagcgatga ggagtgacga tatgaggata cgggtagcga caatgggcct gaccatggta
    18601 gtcgggatgc tgttggtcat gcagggcggg tgttccaaga aatcgattca atccggcggc
    18661 gatgcgcagt cctctgatcg cgggatggcg aagtcgggcg ccccggcgca gtctcaagct
    18721 cagctcccgc ctccgacggg gttggatgct cccagcgcca cgttcccgga cctgtccctt
    18781 tccagcaaac cggaagatcc tgagacgggc ggcttgcgcg ggttcgattc agtgtcgggc
    18841 ggcaaggctc cgtctgagga gcggcttgga ggcggcggca cgatgttggc caaggtcgag
    18901 ccgtccgaaa gcacggcacg ccagattgaa gaaattcgtc gggagcaggc gaaggagcag
    18961 gcggcgtcgg cggaagccgg attgcgcgac gtgtttttcg gctacgatag ctggacgatt
    19021 acggaagatg gccggcagtc gttgacgcag gatgctcagt ggatcaaggc gaatgccggg
    19081 gcgttggtca agatcgaagg gcattgcgat gaacggggca cgctggccta caatctcgtg
    19141 ttgggcgaaa agcgagccaa ggccgtgcga aactatctgg tcgaactggg cgtcggcgcc
    19201 aaccggttgt cggtggtgtc gtatggcaaa gagcggccgt tctgcaacga gcgtagtgaa
    19261 agctgctatc aacaaaaccg ccgggggcat gtggtggtcc ggtcgaaata actgttccaa
    19321 tcatggatga tgtgacatga ttctccggaa cagacgccgg tcaagggaga cctgtcatgg
    19381 acagtgaatg gccttatcga aagacgatga ctgatcaacc gtcgaacgcg aagcgtgtga
    19441 cgccgggcac ctatgcgcag gcagctcgat tcggtgcctg tgtcgtggtc gtgacgggct
    19501 gtgtcttgtt gtcgggctgt gtggcgcagc aggcggatct caagcagacc gaacgagagc
    19561 tccagcgtcg catcaagcaa cagacggaag agcaggccca gaaccgggca cgccaaaatc
    19621 aggaaatcgt gtcgttgcgc gagcaggaca ttccatccct gcgcggcgat gtcgataagg
    19681 ccctccaccg tgcacaaagt ttggatgcgc ggcaagacga cctgctggcc aaggtggcca
    19741 gccaggaatc gaagttcgag cgtcgcatcg gcgaagccga gaagcggtcg gctgaggaag
    19801 gcaagcgctt gggctgggtc gaaaagcagc tggtcgatca agatgccatg ctcaaaggcg
    19861 agcgagaccg gaaccgggct gagctggccg cggtgaccgc tcgtctggat caaatcaaca
    19921 gccatatcga ggccattcag aagaacgttc tggatgcgat gcagaaaact accaccgggc
    19981 tcgcgcaaaa ggtcgattcg cgcctggatg aacagcagaa gttactgcac gggttggaga
    20041 cccgttccca gaacgtcgcg cagctcgatg cccagaataa ggtcttgggc gatcaggtcg
    20101 ggaaattcaa tcaggcactg gtcgacttca agcaggcgct gggaagcttg ggcgaacgcg
    20161 tggtgcaaca ggaccagacc gtcaagcatt tagccgcgac cctggagcag gataccgtgg
    20221 ctttgagcaa gcggaccgat gcgctggccg gaaaaatgga tgccgataac aaagtcaccg
    20281 ccgaccactt caatgaggtc aatcggagtg tcgcctcggt ggcaaaggcg ctggaaaatg
    20341 ccggcggcaa atttgtgtcc cgtgaggacg accatgaacg gcgcctcgat gacacgactc
    20401 gagaactgac gcatgtgcag gcacagatcc agacgctgga caagaatctc gaaaatcaac
    20461 atgcgttcct gaagcaggtc gagcagcatt tggtcgccct gcgagcgaac gccactcagc
    20521 gcagcgaacc ggctcccgcc gtcgccgaag cggcaccgct tccccaggcg attccggccc
    20581 cggttccacc cccggccccg gcgcagacac aggacttcgc atcgtcatcg gctatcaccc
    20641 cccgtgcgga aaatcgtagc gcggcgctgg tggcggatcg ggagtcctac gaacggactt
    20701 tgacccgttt caaggatggc gatttggatg gcgcccgtca ggggtttgcg gagtttctcg
    20761 ttcagcatcc gcattcggac ctggccccca acgcgcgctt ttggttgggc gagtcgtact
    20821 atggcaaaaa ggattattcg cgggccatcg atgcctatga tcaagtgcag ttgaatcatc
    20881 ctgccagcga aaaggtgccg gccgctctct tgaagaaagg gtatgcctat ctggcgctga
    20941 aggatcggaa aaaggcggcg tccgctctga aacaagtgat tgacctgtat ccgaggtctc
    21001 cagaggccaa taaggccatg gataaattga accaactaaa ggagtcgcac taacgatgaa
    21061 gctccgattc gcgggggcat tgcgggtgag tgccatgctg gcttgcgggc tggttgtggc
    21121 gggctgtgca aaacatgctg atttcctcga aatccgggat caggtctcca tcatggcccg
    21181 gactcaggat caggagcaga agcggttcga ggcgatgcag cgccggctgg aatcgctcga
    21241 gcgggtgcgt gagccggaag gcgggaaact gcgtttagac gacgccatga cccggcttca
    21301 aaagctggaa gggcggttag cgaaggtaga agaggcgcag ctcgctcaag cggctgctat
    21361 ccggtctgat gccgctctcg cagaagccag ccgccaggcg cgtatctcga aaccctcagg
    21421 cccgattgaa cctcaagcca ttgtgccggg agttccgtcg atcacgccga cctcggcgtt
    21481 caatctggcg tacaacgact acctcaacgg gaagttcgat ttggccgtca acgggtttca
    21541 gcacttcatc aaggattttc cctctacctc gctgacaccc aatgcccatt actggctcgg
    21601 ggagtcctac tacggtcaga aggattatat ccgtgccata cagtcgtttg agcacgtggt
    21661 caatgagtac gcgggaaatg agaaggtgcc ggctgccctc tttaagctcg ggctctcggc
    21721 ggctgaaacc ggagataccg caaaatctcg caagtatctc aaacgggtca ttgaggagta
    21781 ctccacatcg gacgaagcca agcttgcgaa gacgaagatg gccgagattc gatgaccctg
    21841 aggtgtttgt ccggtctcct ctccgctgag ttatcctccc atcaactcgc agggggcgtt
    21901 tcttcccatg gatatagcca gtagcgtggg aaagattcag gttctcccca gcgatgtcat
    21961 cggacgcatc gcagccggcg aagtggttga gcgcccggct gcggtagtga aagagctcct
    22021 cgaaaacagt ctcgacgcgg gcagtagcgc gatcaccgtc gaaatcaaag acgggggcct
    22081 cggattgatt cgggtcagcg acgacggcga aggcatgtcg cgtcgcgacg cctctctggc
    22141 cttcgagcga catgctacca gcaagctcca gtcggatgac caactcggcg cggttcgtac
    22201 gatgggattc cgcggagaag ccctgccgag cattgccgcc gtctcgaaag tccgtctgac
    22261 gactgtggcc cgtcacgatc aggtcggcac acagctgtgg cttacgggag ggaccctcac
    22321 tcgtgtagag gatgcggccg cgatccccgg aacgacgatc gaagtgtcgg agctcttttt
    22381 caatacgccg gcccgccgaa aatttctcaa gtcgactacc acggagttct cccacatcag
    22441 ccatgtggtt cagcaggccg cgttagcctg gccgcaggtg tacatgcggc tcgtgcataa
    22501 cggatacgaa gtgtttgcgc tgcctgctgt gtcctcgccg cgcgatcgcg tgctccaggt
    22561 gtatcgggca gcgttcggtg agcgagcctt ggctgtcgat gtcgagcgcg atggtctgtt
    22621 gctgaaaggg ttcatcattg atcccgtccg ggcccgtgcg ggacggacgc cgcaggaatt
    22681 atttgtcaat cgtcgcccca ttaagaacag cacggtgcaa catgccgtca tcgacggcta
    22741 tagctcgttc ctggccaagg gccatgcacc gctcttcgtg ttgtttctgg atgtcgagcc
    22801 gcaccgcgtg gatgtgaatg tgcatcccac gaaacgtgag gttcggttcg ccgataccga
    22861 gcagatccac cagctggtcc gctctgccgt acgccagacg ctcggtcggg cacaggtgga
    22921 agcgtcgatg gcaggggcgg ctcatgctga gatgaccggt gtgatcccgc cgactctctc
    22981 tttcccagaa agggaacgga tgtcctttgg ggaagcgccc cccgggccaa tggccagatc
    23041 gaaggcttcc gtcacgccac ctgattccgc tgagagccaa acttctttcg ttggagaagg
    23101 cgccacggcg tatgcctcac ctgcatccac agatatcgtt gcactcgggc aaatgaaccg
    23161 tacgtatttg attgctcagg tcgggaacga actccaggtc gtcgatcaac atacggcgca
    23221 tgagcgtgtg ttgttcgagc gactctggcg agcgtggcag gggcgcgcgg tgacgtccca
    23281 accactgctt ttgccggaac cgctcgagtt gccggtgcag caagccgtga ttctgcagcg
    23341 acatctaccg gagttggaac gactgggatt gctgattgag ccatttggac cttcatcgtt
    23401 tctgatccgg agtctgccga tcatgttggg tcatcctgat ttgtccgcct tggtgcagga
    23461 cctgattgat gatctcgaac agtgggattc catttcgtcg ctggaaacga aggtgaagcc
    23521 tattctggcg tcactggcct gtcacgcagc ggttcgcgcg ggccggtcga tggcattgcc
    23581 cgagatcacc cagctggttc aggattgggt cgcggaaggc ctgatcatga cctgtccaca
    23641 tggacggcgt gtggcgttcc gtctgtcggg agacgaactg gcgcgtctgt tcgatcgcgc
    23701 ctaggggaag cacacggaga gatatgatcc ggctcacgga atccgtcctg gcgtcgcggc
    23761 cgctcgtggt actggtcggg ccgaccgccg tggggaaaag cgacgtcggt cttcggctgg
    23821 cccgcgcgtt ggacaccgac ctcttgacgg cggactcgcg ccaggtctat cgcgggatgg
    23881 atatcgcgac ggataagcct gccgtggcgc agcagcaggg ggtgccgcat cgactcatcg
    23941 acctcgtcga tcctgatgaa tcgtttaatg ccgggcagta tcgccagctg gcgttgcagg
    24001 aaatcgaacg gctgtacgga gaacggcggc tcccattgat cgtgggcggc accgggctct
    24061 acgtgcgtac gctgattcat gggctttgtg atgccccgcg ggcggatcag gcgtttcgtg
    24121 actcgttact gcaaaaagct caggggcagg gacgattttt cctccatgcc gaattggcgc
    24181 aagtcgatcc tgaactggcg gcaagactgc atccgcacga tgaagtgaaa atcgtgcgcg
    24241 ctctcgaggt atttcatttg tccggacggc ggctctcgga tgtccagcag gaacatcgct
    24301 ttgccgaaca accgttctcc gtgctcatga tcggattgaa tcgcgatcgc gcagaactgt
    24361 accggcggat cgatgagcgg gtcgaggcga tgtttgctcg aggcgtcgtc gaggaaaccg
    24421 cagcgctgct ggcgaaggga tacggccgcg agacgggtgc catgaagggg ttagggtacc
    24481 agcaggtcgc aggctatctg tccggtgact atgaccgcgc ggaggcgctc cgtctgctga
    24541 aacgcgatac cagacatttt gccaagcgtc agctgacctg gtttcgaaag gagcctggtc
    24601 tgcagtggtg gatgctgacc gagcaggata ccgcagagga cgtggcgggg cgtctgctgg
    24661 agaccattca cacgtttgta cagacactga atgacgagcg ccagccgcat cggcctgcgc
    24721 cgcgtaccat agaaatggaa tcgacatcat gaagaaagca aagaagacca ttcagcctgc
    24781 tgtcggtatt atcggcggga gcgggttgta ccaggtcgaa ggattagagc aggtccgcga
    24841 ggtacgtctg cgcacaccct tcggcgcacc atcggatgcc attgtggtcg gagtgctggg
    24901 cggcatggga gtggcgttcc tttcccggca tgggcgcggg caccggatca accccagcag
    24961 catcaactat cgcgccaata tctatgcact aaagtcgtta ggggtgaccc aagtcatttc
    25021 aatcagtgcc gttgggagca tgaaggaatc cattgaacca ggccatgtgg tgttgcccga
    25081 ccagtttatc gatctcacga agcggcggat ctcgacgttt tttgacgaag ggatcgtggc
    25141 gcatgtcggg ttcagcgagc cggtgtgctc ttccttagcc gatacgctag aggaggcggg
    25201 acgatccgcg ggcgcgacgc ttcatcgcgg cggcacctat gtgtgcatgg aaggaccgca
    25261 gttttcgacc aaagcggaat cccgcctgta tcgacaatgg ggcgtggatg tgatcgggat
    25321 gaccaacatg cctgaagcca aactcgcccg cgaggccgaa ctgtgttacg ccacgatggc
    25381 gctggccacc gactacgatt gttggcatga gacggaagaa gcagtgacgg ttggggccat
    25441 cctggccacc ttgcaccgga atgtggccct ggctaaggaa atattgaaga cggcggtgcc
    25501 gaagttggat cccgaccggg cctgtgcctg tcggcaagcg cttgccacgg cactgattac
    25561 tgccccggac aaaatgtctg cttcggcaaa acgacggttg aacctcttga tcgctcccta
    25621 tgtgcggacg cggaaaggaa aacggtgagg catgggtaaa ttgctggtag tggggtcggt
    25681 ggcgctggat accgtgaaaa ctcctttcgg cgaggtggcc gaggtacttg gcggatccgc
    25741 gacgtatttt tcgacggcgg ccagttattt cacctcggtc gatctgatcg cggtggtcgg
    25801 cgatgacttt cctgagcaac atgtcgcgtt cttaaaaagc cgaaaaattg atttggcggg
    25861 attggaacgg cggccaggcg cgacgtttcg ctggaagggc gcctattcgc atcaactcaa
    25921 cgaggcgcag acgctcgaca ccaagctgaa cgtctttgag acgttccggc cgaagatccc
    25981 ggcccagtac agctcgcccg atgtgctctt tctgggcaac atcgacccga acctgcaact
    26041 cgacgtgctg cagcaggtga agcggcccgc gttggtcgcc tgcgacacga tgaatttctg
    26101 gatcaacggc aaacgtgatg cgctctggaa cgtcctgcaa cacatcgaca ttctgatcat
    26161 caacgacggc gaggcacggg ccttgggtga ggataccaac ctcgtgaagg tcgccaaaaa
    26221 gatcctcgcg cggggaccga aacatctgat cgtgaaacgc ggcgaatatg gtgtgctgat
    26281 gttcaacgac aagcaggtgt tcggggcgcc ggcgtttccg ctggatgatg tgcgcgatcc
    26341 caccggcgcc ggcgatacct ttgccggagg cttcctgggc tatctggcgg cgacgggaaa
    26401 ccgttcaccc gaagccatgc ggcaggccat tattttcggg agtgtgatgg cctcatttac
    26461 agtagaagcc tttagccttg accgattgag gatcctagat tacaaagaga ttgaggcgcg
    26521 ctttaaagaa ttcaagcggc tcacgcattt tgaggatatc ggcgcatgat cgtggttgat
    26581 cgacaggaaa ctcggagctg cagggccagc ggtatggtgg ggtcatcctg cctcgtgttc
    26641 ctgctggggc tgtctgtctt gggcgggtgt gccaacgaag agaacctgcg caagtccaaa
    26701 ggattttacc aggagggcgt ggcccggctg agttctgatc agcagcaggc gtatgtgtcg
    26761 tttcaaaaag cggtgaagct gaatcctgac aataaggaag cgcactacgg actcgggcac
    26821 atctatgcct cgcaaggacg actcaagctg gctgaagaat ccttccgtga ggcgattcgg
    26881 atcgacggcg actatgccga agccaacacg tacctcgggc aggtcttggc cagtcaagat
    26941 cgatggaaag atgccatcgc ggcgtaccgg caggcgctca gcaatccgct ctatcccaca
    27001 cctgacctgg cgcggtttca gctggggaaa gccttgatgc atgaaggtga tctgcagggc
    27061 gcgatggagg tgttggagga tgcgacgacc gtgacgccgc ccaatgtgcc gcccgcgatg
    27121 ctgcagttgg agctggcgcg tgtgtaccac aagcttggat tcgacgcgcg ggcgcgtgag
    27181 gctctgtcga aagtgtcgac gttggataaa ggtggcgagc aggcggctgc ggcgcaggaa
    27241 ctcctcggta agctcaaacc ataggcggat atcatggaat cagtgggtga attttttcgg
    27301 caggttcgcg agaccaaagg gctgacggtg gatgaggtgg cctcgaagac ccgaatccgc
    27361 acagactttg tcaaagcgct cgaagaggga aatttcgcca aattgccaga ccaggttttt
    27421 gcgcgcggat ttgtccggtc ttatgcgcgg tcgctcggat tggatgagga agatgccatt
    27481 catcgattcg tgcagtctgc cggcgccttt tacgaaaagc agggtgagcg cgaacgcttg
    27541 cggcaacgac aggtcgaaga ggagcgccgt cgccgtgcca accgcaaggc ggtgggggtg
    27601 gccatcgctg tcgcgattgc gacgctggtg ttcctgttga gccgtgagca gacctctacg
    27661 ctggtgagac gctccggacc ggatgcacca accgtcagta agaaggtggc cccatttgcc
    27721 aaggatgcga aggaggcggg ttcccgccct gcggcggagc tgccgcctcc cattgctcct
    27781 ccgctcaaac cggctgagcc ggcggttgtt cctgcgaagc ctgcccaaga caaaccggct
    27841 ccggttgcgc aagctccagc gcccgttgcc gtggccaaag cgccgttgcc gtcggatacg
    27901 gtcgtgactc agccctctgc ctcaatggga tcagacggtc ctctggcagg attgtcggtg
    27961 gatggtcccg tcgggtcgga tggtccgctc gtcctcgacc ttgcggctac ggaattgagc
    28021 tgggtggtcg tccaagttga ttcggggagc caccaggaag cgctgctgcg cccgggtgaa
    28081 aaggctcagt ggaaggccca ggatcagttt acggtgacgc tcggcaatgc gggaggcgtc
    28141 cgcgccgaac tcaacggcaa accgcaaaag ccgttcggcc ccagcggcaa ggttgtccgg
    28201 gacgtcgtga tcaaacggtg acggtgtcgt ctcactagct cgacgctccc cgggtcgtca
    28261 ggcgtttcgt gcattcctat tctcaccgcc tgctcactct ctccaatcca tatgtcgtga
    28321 gggtgtctat ggccctcctg ctcgcactcg aatgaggcga ggaggaggcg tctgaggcgc
    28381 aaaggtgtca cggctggatg gctgtacgta cttgccgctg atctgaatag tctaaatgtg
    28441 gtgaaatccc gcgatttttg ctgttctgcc gctggcacag cccttgattc tccttcaagt
    28501 cagcatggat gaaacagaca aggctgaggc gggccattcg cttgacaaga cagaaaacgc
    28561 gttgctatag ttcgcctgct ttatcggctt tgtcatcagt ttttgccatg ctgattcgga
    28621 ccgagagtta ttgttcacgc ggtgggttca acacaaagga ggagttctga tggggtattt
    28681 ttcta
//
LOCUS       DAOQPD010000050        27995 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_771_length_27995_cov_22.772477, whole genome shotgun sequence.
ACCESSION   DAOQPD010000050 DAOQPD010000000
VERSION     DAOQPD010000050.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 27995)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 27995)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27995
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_771_length_27995_cov_22.772477"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..926)
                     /locus_tag="PK063_12150"
     CDS             complement(<1..926)
                     /locus_tag="PK063_12150"
                     /inference="COORDINATES: protein motif:HMM:NF016241.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF481 domain-containing protein"
                     /protein_id="HMZ97849.1"
                     /translation="MHHRHVFSLLLWQRALLLFSLWLATPAAADEIYLLNGDRLTGTI
                     VKMEENLLTIQTDYGGEIKVDWKKVQRLTATSPIKILVPGESRDVLRDFVYGTQGQRE
                     VSEAGQDTSTPLSDITAINLEPFRVAGTVSVGGNNTSGNSSTKAFNSAARLTLYAHRQ
                     RLLVEGKYNYGQANDQVTARNSLASLKHNYFISKQIFIETFGMLEKDTLQALQLRSTI
                     GSGLGYQFYETPTTTLSLSAGIAHVNEHFTNSPNTQTPSGRWSLRWEHSLWPDRVKVF
                     HRHEGFWDINAGNAFRFNADQGLRITVYKNLF"
     gene            complement(1075..2268)
                     /locus_tag="PK063_12155"
     CDS             complement(1075..2268)
                     /locus_tag="PK063_12155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97850.1"
                     /translation="MTIPSLLLRGLIALTVFMNLAGCLSPPTLTRAVVSYDNAITDSI
                     SKQLLLNIARAHHHQPVHFTGVSNVAATFDFRINAGATPTLTGEAGKTLLPVFGGSVA
                     ENPTISIAPIDGEEFTRRLLTPFQETKFTLLLRQGGDIDLLLRLMAKELRVDDQGEDI
                     AYRNSPTDKAGYEMFRKVVLHLSAIQDANRLYAESMLFERTWTIPAESVTAEGFKALE
                     QDYLVAYDPQQKTYRLRKPVSGRILITNYDPNTLPQEERVRLHEEAERSPMNDVSFDI
                     RPGHYGGEWPLKGEFRLRSFNTMLNFLAQSVEEEPEYAVEKDNRTPPFMDNPVKTMDL
                     LVQESSPSESDLTVQSHGKYYSVNITGPLARWNREAFKLLYQLFQMTVTEVSRSGVPS
                     ITIAK"
     gene            2449..3219
                     /locus_tag="PK063_12160"
     CDS             2449..3219
                     /locus_tag="PK063_12160"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97851.1"
                     /translation="MRHSVWVGVMTLLCFTGCGSSAKLISGLSIEELKPVPGILSSAR
                     LLKGTIRSITGDRVEVDTGERAPRYLSLEAGGDEARGLQVGGAVEIMVNDHDDIVAYQ
                     RPAETPPTKVFRGSLGKVFNPQKERVTIRLDTGRDVGFYARSVAMEKLAALEVGETAD
                     FAVDRAYLLVDVLSLGKPRDLGVGSSLPAPQRRVEGAFVTIGDGRMRLRMKIDDIQSF
                     PVRPLLQPAIEQLSPNETVSIYLDGQGQVIDMVRTARR"
     gene            complement(3226..>3918)
                     /locus_tag="PK063_12165"
     CDS             complement(3226..>3918)
                     /locus_tag="PK063_12165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HMZ97852.1"
                     /translation="DVTDSASIAAASHTVAAMVGDRGLAGLVNNAGIGVAGPIELLPL
                     ADWRRQFEVNVFGLIAVTQTFLPLIRTGHGRIINMGSIAGRASMPFMAPYAASKHALE
                     AITDALRLELQPWGIRVALITPGAIATPIWGKTRKEVDTWDATWSPDLKDMYQEGFTR
                     IKEAATAAGEQAQPAKVVAEAVAHALRSRWPHTRYLVGSDATIRSWLALLLPDRLNDW
                     IITRIVKLPRRR"
     assembly_gap    3919..4018
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            4101..5501
                     /locus_tag="PK063_12170"
     CDS             4101..5501
                     /locus_tag="PK063_12170"
                     /inference="COORDINATES: protein motif:HMM:NF027442.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4832 domain-containing protein"
                     /protein_id="HMZ97853.1"
                     /translation="MHTEKCKWALLLMMGLSLAAYVSPLNAGTDQKGVVATEKLVTVQ
                     PREIDDVLDNPGMGFADFHFGFGHPPKPDEYPHTTVAYFRWPWAELEPAEGQYNFALV
                     DGVIAQAKAKGETLAIRIVSEYKTGTPQWLLDKGVASIKETDGIFPDYNNPIFLDYHE
                     RLIRAFGERYGRSLDIDHVDIGSVGCWGEWNTACCVGAETQCKAYYPTEANQLAITDW
                     YLKYFSGTPLVMLHGGQLQYAASRGAGWRADCFGDYGYFSPDWNHMEHAYAPVLEAQV
                     VADAWKQGPVQMEVCGYIHEWYERGFDLDRILEKGLEWHVSVLNAKSKPVPAAWRPRF
                     NEFLKKIGYRFVLRELTHPASIGAGESLIIHSRWDNKGVAPIYHAWPLAYRLRSGTDE
                     VVAQWTSAADLKRWLPGPSHLAEDAVVVPSTVPAGVYTLDVGILSEDAKSATVELAIE
                     GKRTDRWYAVSRVEIR"
     gene            complement(5581..6507)
                     /locus_tag="PK063_12175"
     CDS             complement(5581..6507)
                     /locus_tag="PK063_12175"
                     /inference="COORDINATES: protein motif:HMM:NF024970.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ97854.1"
                     /translation="MIFPQPQLLLVDDSTLNLKILREFLPERQYRCTTAQDGRQAWDM
                     LEAEPDRFHAVLLDRIMPGMDGMEVLHKMKQHDALNQIPVIMQTAASTHQQTLEGLQA
                     GAYYYLATPFDQATLQAIVDAAVRDHISYLDIRQDLRRTTTTMRLLESGTFHFRTPEE
                     ARNLAMLLAHAYPDADRVVTGILELTLNAIEHGNLSIGYKEKSRLIEEDKLEEEIAHR
                     LSSPPYSSRVATAKFSRLPQGLSLHITDQGNGFDWQRYMDFDPERAFDTHGRGIAMAN
                     KVSFDQIEYRGNGNQVMTVLRLEQAAAPALAV"
     gene            complement(6694..7371)
                     /locus_tag="PK063_12180"
     CDS             complement(6694..7371)
                     /locus_tag="PK063_12180"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HMZ97855.1"
                     /translation="MRHVTGAVSAVVLLISSLSWAAASEPANDEQKTLYALGVAISQS
                     LTPFTLNEAELEFVKSGIADGVLKRSQKVDMNVYGPKIQQMQQVRSNALADVEKKAGA
                     AFLAKAAAEPGAKKTESGAIVTTIKEGKGATPKATDTVKVHYHGTLTDGTVFDSSVKR
                     GEPATFPLNQVIKCWTEAVQLIKVGGKSKLVCPSGIAYGDRGSPPVIKPGATLVFEVE
                     LLDIVKQ"
     gene            complement(7680..8624)
                     /locus_tag="PK063_12185"
     CDS             complement(7680..8624)
                     /locus_tag="PK063_12185"
                     /EC_number="1.8.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004364 - glutathione transferase activity
                     [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HMZ97856.1"
                     /translation="MTPQPQFPNEHTESGEFQRQEDAFRQWVTDDGRSGLPAAAGRYH
                     LYVSLACPWAHRTIIVRALKQLESVVGMTVVDPIRDEQGWAFRTGQGHSIDPINGFHF
                     LSEAYHLTDPTYRSRVTVPVLWDTVTKRIVSNSDDDLMRMFNAEFNRFTISTLDLYPA
                     ALRADIDEMNTFLYEQVNNGVYKAGFATSQRGYEQAARSLFAALDQLDTRLSQRRYLF
                     GPQFLESDWRLFVTLIRFDAVYHGHFKCNVRRIIDYPHLSGYLKDLYQVPGIADTVNL
                     DHIKRHYYVTHDDINPTQIVPIGPQLDLESPHGRDKFS"
     gene            complement(8720..9229)
                     /locus_tag="PK063_12190"
     CDS             complement(8720..9229)
                     /locus_tag="PK063_12190"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97857.1"
                     /translation="MAEDPPHPSLFQNVGFGLGLGWTHNLGARRVESVSVTNRIVRID
                     DERNDLVRAMPEVHLWIDRWDEQRWSWGPFLAVAPGSRIIDAVGGGLMVGYRPHRSDQ
                     YSFNFGIGGILDLDTQVLGDGLVANEPLPPRETSARTKHTTGAGLLVLFSVGWDLSAP
                     HQVSPPGRK"
     gene            complement(10911..11417)
                     /locus_tag="PK063_12195"
     CDS             complement(10911..11417)
                     /locus_tag="PK063_12195"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97858.1"
                     /translation="MVRLTTHRLESPRQWWTSLAMGCSVLLFALPVFAAESSGPWECS
                     NYTGDAHTRCLQAFIEIQREKISKLEAEVQLQQSTVGQLKDQADRQNAMTAELQRQMS
                     QQSSAPSTYGYVSPGIAPGLLYGYPSVGFGLYLGRPWIYGSPFYARPYAWGPRYYRPY
                     YGRWHRRW"
     gene            11583..12533
                     /locus_tag="PK063_12200"
     CDS             11583..12533
                     /locus_tag="PK063_12200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NmrA/HSCARG family protein"
                     /protein_id="HMZ97859.1"
                     /translation="MGEKQVIAVVGATGMQGGGLVRAILANPASGLAVRALTRDVNSD
                     KAKELARLGAEVVAADVHDVESLKRAFSGAAGAFCVTFFWAHLSPEKEYAEAEAMAKA
                     AKAAGVRHVIWSTLEDTRRWVPLSDNRMPTLMGKYKVPHFDAKGEADQLFKQLGLPTT
                     FLLTSFYWDNLIHFGMGPKPGPDGALAFTLPMGEARLPGIAADDIGKCALGIFKKREA
                     YLGKTVGIAGEHLTGSQMATALGKALGREVRYNAVPPEVYRNFGFPGADDLANMFQFK
                     RDFNAVFCAAREPAIARALNGGLQTFAQWLEVNKARIPLS"
     gene            complement(12561..12779)
                     /locus_tag="PK063_12205"
     CDS             complement(12561..12779)
                     /locus_tag="PK063_12205"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97860.1"
                     /translation="MRYSLYFAWVLAVLSICILTTLASFPVLTNGERHPEPRITAGPE
                     KLRTIKIHRLRCNPFTSSCQLSRQKSQH"
     gene            12999..14489
                     /locus_tag="PK063_12210"
     CDS             12999..14489
                     /locus_tag="PK063_12210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HMZ97861.1"
                     /translation="MLLSFVILYLACSVGIGLYAATRVHNTKDFAVAGRSLPLPVVTA
                     TVFATWFGAETVLGISATFVKDGLRAVVADPFGSSLCLILAGLWFARRLYRLNLLTIG
                     DFYRLRYNRAVEVLCTLCIVASYLGWVSAQIKALGLVFNVVTDGAMSQSAGMMLGAVI
                     VLTYTTFGGMFSVAILDFVQITIIMGGMLYIGSVISGLAGGVGTVVTHAAEAGKLDFF
                     PPAQIEAWIPFVGAWVTMMFGSIPQQDVFQRITSARNEDTAVRGSVLGGTLYFVFAFV
                     PMFLAYSATLIDPAQVAGLLERDSQLILPTLIVQHTPMAAQIIFFGALLSAIMSCSSA
                     TLLAPSVAFSENIVKSLMPTISDRGLLAVMRSVLVGFTALVLLFALNSEASIFKMVES
                     AYKVTLVAAFVPLLAGLYWPRATTQGAICAIVTGLATWLMLEGTVTPDQVWPPQLVGA
                     LMAAGGMVIGSLLPQWITHPATIDVPVGHRSHSMPVESHTGTHPSP"
     gene            complement(14486..>14868)
                     /locus_tag="PK063_12215"
     CDS             complement(14486..>14868)
                     /locus_tag="PK063_12215"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ97862.1"
                     /translation="GTEIILLVEDEPSVRLLTQHILRTHGYTVHEAEDGFQAMDLIRR
                     NNLHIDLLITDLVMPGMNGKELAMRLRSHFDDLKVLYMSGYSDNLPVTGGESQGQTTF
                     LQKPFSPEDLIRLVREILHSVSPA"
     assembly_gap    14869..14968
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<14969..16221)
                     /locus_tag="PK063_12220"
     CDS             complement(<14969..16221)
                     /locus_tag="PK063_12220"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HMZ97863.1"
                     /translation="MDRPAHTDPALELQSQQVSVLYRNMPTGVLASAVNAAILAAVEW
                     SVVPHTPLLVWVAILWIVAGARALLIYNYRRTTPATWSSADWHRWMLVATTMAGVGWG
                     GSVYFLTPEIPLAYELVQLFVLGGMTAGAVSVLSVSFQLFLCYALPVTLPTLGHLFFS
                     GYDFHVIMGVMGTLFLLATIHSSWTFNHVLLSSLRLQLEKLSLVQSLTTRSEAVERLN
                     RDITKEIHDRRVIEEQLRTAQSDLEHRIAERTADLAHANSRLQDEVREHRRTEGARLS
                     SEKRFNYLTDNLNQGVWFAQAQPPQVLYVNPAFERIWGLPAARFYENPKLWRDCVHPD
                     DQRMVTEVYDTELTRPTGRDVQLLYRIIRPDGQTRWIHDRMVIHRTDTGEVDSLSGIT
                     EDITDARELEDQLRQAQKMEAVGRLA"
     gene            complement(16336..17793)
                     /locus_tag="PK063_12225"
     CDS             complement(16336..17793)
                     /locus_tag="PK063_12225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein transport protein"
                     /protein_id="HMZ97864.1"
                     /translation="MMRFFTAPASSETDPPTASRETVAPGRKGRTTARLLLLTGALLA
                     AWSTIAPGSVLAGSFRIYDHSASATGQASAFTAQADDASAGYYNPAGMTQLRGVQLSA
                     GTTLIAGGFSFQNGAGTQANGDLRGSVAVPPPSNLYITANLKDLGIGSSDSTAVGLAV
                     FSPFGTLTRWPDSSPFSTATTKAAFELIDIRPSIAFRPLPDLAIGLGADVYTFSGAFG
                     EGQVERQFRWPGGLGIPAGTGMELNGRDTAAGWNASLLYTPLRNEDGKPLVNIGLIYR
                     SQATLHLDGQLLAGGTHIADARTTFVVPQVLTGGIALWPVRNKEREWKLELDVDYTGW
                     KSVRNLDSHLSNGITVATPANWISGYTVMIGTEHKWLNPASLPDWDIALRAGYWHSQK
                     AIPDQTFNPAIPDGDNHAVSTGVGFMCRDNGRFLGVIPCGGASKLSPKGLGIDLAYQA
                     ILYESRTVAGNVNPTVNGTYRTTLHVGSLNLRVNF"
     gene            17979..>19006
                     /locus_tag="PK063_12230"
     CDS             17979..>19006
                     /locus_tag="PK063_12230"
                     /inference="COORDINATES: protein motif:HMM:NF013106.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HMZ97865.1"
                     /translation="MRFVRRWLLRALVAVTGILLLVLGSALAYGLYLSASLALPAGDE
                     HPPRLIYGAPFLLKPDLDVVSSHLIERLSRLGYQAVDTPVRAPGEFRVSPGQIDIYLH
                     EFSDLHLRPMPARLLLEQGRVTRVLSIQTGDELFPAYLEPQLISGLRGASRQVREWVS
                     YDDLSARFLDILLAIEDRRFFSHPGIDPIAVGRAVWTNVTKGTVIQGGSTITQQLAKN
                     LFYSPQRTFGRKLKESIAALVLETKYPKKAILESYANEIYLGQVGSVSIYGVGEAAHR
                     YFGKRVDTLSLEEAALLVGMIKGPNTYSPLRNAALAKQRRDVVLGRLHEQGLINDEAW
                     AQAIKTPV"
     assembly_gap    19007..19106
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <19107..20129
                     /locus_tag="PK063_12235"
     CDS             <19107..20129
                     /locus_tag="PK063_12235"
                     /inference="COORDINATES: protein motif:HMM:NF013100.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HMZ97866.1"
                     /translation="KTGGILAMVGSRDYRTSQFNRAVQAKRQPGSLFKPLVYLAAMEA
                     RRELNGGQPVTAATSIVDEPVTFESATGRWTPQNYDHKFHGTVSLRTALEQSLNIPAV
                     KIAQLVGTKRILSLAEKLGIRSPLADNLSIALGTSGVSLLEMTSAFGVLAHDGVSMTP
                     TALQAVMTSEGDPAWHHTPARHQAVSPQAAYVMTSLLKGVVERGTAAKAKAMGLRGIV
                     AGKTGTTDGYRDAWFIGYTPDVVVGAWVGFDDEDALHLTGAQAALPMWVEFVRQILPA
                     APRDFVMPPAVITRDIDPQSSQLATSKCPQRSAELFIEGTEPSVYCEVHGSGMWERVK
                     RSFGFF"
     gene            20216..20656
                     /locus_tag="PK063_12240"
     CDS             20216..20656
                     /locus_tag="PK063_12240"
                     /inference="COORDINATES: protein motif:HMM:NF016408.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HMZ97867.1"
                     /translation="MMKKPGFVESDNITLLAKGVLLRGEIHVEGTVRIDGRLEGDLKT
                     SGTVVIGEDGVVQGTITAGTIISSGKIKATVRATERIQLLKTGLLVGEVHAPAFSMED
                     GAKFQGLSDMGVTSWGDDAQKLPGNVREIASQRPKAVAMAGENA"
     gene            20831..21913
                     /locus_tag="PK063_12245"
     CDS             20831..21913
                     /locus_tag="PK063_12245"
                     /inference="COORDINATES: protein motif:HMM:NF013740.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HMZ97868.1"
                     /translation="MNRRQIFAACFFGVLLALLYQMALMFRPFVFPVLWAVILAHLCF
                     PLHIRLTAWLGGKESHSAVLLTLAALALVVVPLVVLSVMLVKEAGSAERAVREWIASG
                     GVQQLPDRLSGLPGGSVAREWLERFTGQESDLEQFVLSSAKTFSKFIVGELSDLVRDV
                     FMLVADFLVMVFTLFFFFKDGRHWLASLYGLIPLEASHKDKILVRLDQTIRAVVKGIV
                     LTAVAQGLLAGAAYAVLGVPFPMVLMALTILLAPLPFGGTALIWGPVAGYLLWSGTVG
                     KGLVMLAWGIGVVSTIDQILKPLFIGQGAQIPVLLLTFSVLGGLAAYGILGLFLGPIL
                     VGLFLTALQIYRDEYQLQPASPIVRS"
     gene            complement(21936..22487)
                     /locus_tag="PK063_12250"
     CDS             complement(21936..22487)
                     /locus_tag="PK063_12250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3365 domain-containing protein"
                     /protein_id="HMZ97869.1"
                     /translation="MALFLACVSTYSLQAKDLTPPAGISPEKVADFVHAVLDADRTIY
                     TNQVVNRMQAKGIVSAMEHWEHENALPLPAQFLQHSGKLVAESGRGIRYRLISLWPIY
                     QRNAPATDLERQALESFAQTPDRPFTGIVTSGRKQFFQAVYADRAISAACIKCHNSHP
                     LSPKRDFALNDVIGGMTITIPLD"
     gene            complement(22514..24991)
                     /locus_tag="PK063_12255"
     CDS             complement(22514..24991)
                     /locus_tag="PK063_12255"
                     /inference="COORDINATES: protein motif:HMM:NF014763.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ97870.1"
                     /translation="MTITWRPFSNPLGWGLKRKLIVSMLLVGVVPLLLGLSMAFLQGS
                     KEIQVVSGESFQALATEAARKLDLLVAEEVARTSRIATHPEIIRQLEHHRDLLQTADK
                     TLSATTITQQRTRWAARDPIAVKAITENRTAVLLRSFYAGAQNESDLLLPQVVRAATK
                     KLFITDVQGNLFAALTTFPSFSNADSPWWKGTYNKGVGQLYIEDLHFDEQAKAYVFSI
                     SLPIMDSLKYEVVGVLHRVIDAKEFFSPSTHPIRFGKTGHVMLIDSRGIVLSCPILPT
                     GVRLSDPALIPQVTVREPGWVTADSDGHGGQGTAIIGFALLPETSRATNGALEVGAWH
                     TFVWQSSDELFSPIRHLMLWMLILASIALFLLATLGYFAASRIVTPVRRLQEAARLIG
                     RGELQEPIQIRTGDELEDLAVEFNRMHKQLEASFAGLSTQVEEKTQEVQYLQKATDQV
                     LDAVPTPIIMVDQQGLVQYMNKASREAVQADSWSSRPLFDLLPVDEEHRQALQRDFRA
                     VEEGMSLAPVRHDAPPLLKPARDPLNQTIGPAPASSRRELRIGPHLYQYEWFPLESRS
                     GAGKRFGLVLRDTTDESRLQDQLIQAEKSGSLDVLTAGIGHELNNPLFGILGLGEAIQ
                     EEGDLARAKGYAQDIVGHGRKMAAIIRDFTGVATRESKSQRMPVDVTAQLEQALAIVQ
                     TSHECLGLNVQKHYVPVSPVTALPDQLRLAFINVLTNAIQAMNGQGNLWLTTEEQDDV
                     ITIKIRDNGPGIPKQHLGKVFDPFYTTKGQGEGSGLGLTVAQRLIKKFGGEIRMESPP
                     EGQGTTCVITLPAEKAAVRKEEPCIST"
     gene            complement(24988..26037)
                     /locus_tag="PK063_12260"
     CDS             complement(24988..26037)
                     /locus_tag="PK063_12260"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ97871.1"
                     /translation="MTLTSTKIAIIGAGRGGTALLELLHQIPDVDIVGIADKDPAAPG
                     LQRAKDLNVPVEEQVYDLIRNHGVNLIMDVTGDPSMAPFIQAMKRPGAEVLSGATTRL
                     LWKLVQHQSKLEAELFQADKLAGLGSFAAGIAHDINNPLQLILGLAENLTDEQDLTVV
                     HEQARDITEAVKRTSAICRDLTRYARRNGTGEDIMVNLNTKLDEALRIARYAVTLQDV
                     TVVKRYAEDASVLGNPDELLHVFVNLITNAVQAIQDRGTLTLHTNVGPDGQVSASVSD
                     TGCGIPKEAFSKIFEPLYTTKPPGKGTGLGLYNVMSVISKMEGHICVESDVGVGTTFR
                     IEFPQVQPTTSCAPL"
     gene            complement(26153..26587)
                     /locus_tag="PK063_12265"
     CDS             complement(26153..26587)
                     /locus_tag="PK063_12265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ97872.1"
                     /translation="MGEFKSGFFMSETACNGRVLVVDDEPDIRKVVRMTLQKAGYEVI
                     EAENGEKAIEAINTGENRLLLDVLICDIRMPKINGVEAIAYFQQEWPRVPIIVLTGFP
                     DTDMATSFLRSGVVDYLVKPVEGEKLRTAVARAMEQRELAQL"
     gene            complement(26873..27235)
                     /locus_tag="PK063_12270"
     CDS             complement(26873..27235)
                     /locus_tag="PK063_12270"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97873.1"
                     /translation="MSQTKSRQPRPLVQTTLFVLVLVLGCQATLSVRTASAAGSGSEA
                     IQGLGSYFLTLPYGGIKMAVAVLGAVAGGMGFIFTGGDKATADKIWGPAIGGEYVVTP
                     QHLRGEKDLHFFGNPPAK"
     gene            27400..27645
                     /locus_tag="PK063_12275"
     CDS             27400..27645
                     /locus_tag="PK063_12275"
                     /inference="COORDINATES: protein motif:HMM:NF013851.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BolA family protein"
                     /protein_id="HMZ97874.1"
                     /translation="MITAEAVTTYIRQMFPDAAVTVIDKTGTQDHLIVRVISTGFADK
                     NLLDRHRMVYQALAGPMKDGRIHALEITAMTPDEVKK"
     gene            27656..27985
                     /locus_tag="PK063_12280"
     CDS             27656..27985
                     /locus_tag="PK063_12280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin domain-containing protein"
                     /protein_id="HMZ97875.1"
                     /translation="MADPIEEEIQREIQANKILIYGKGTKTMPMCGFTRETMHFFEKY
                     GYPYELIDVLSQPAKREALTKLTNWPTLPKVFIDGQFYGDTDILDPMEAKGEVVPLLK
                     KAFGAES"
BASE COUNT         5399 a         7567 c         8705 g         6024 t
ORIGIN      
        1 aaaaacaaat tcttgtagac cgtgatccga aggccctgat cggcattgaa ccggaaggcg
       61 ttgccggcat tgatgtccca aaatccttca tgccgatgga acaccttgac gcgatccggc
      121 cacaggctgt gctcccaacg caggctccag cgtccggaag gggtctgcgt gttcggacta
      181 ttcgtgaaat gttcattcac atgggcgata ccggccgata acgaaagcgt ggtggtaggg
      241 gtttcataga actgataacc caagccgcta ccgatcgtgg accgaagttg cagcgcctgc
      301 agcgtgtcct tttccagcat gccgaacgtt tcgatgaaga tctgcttgct gataaaataa
      361 ttgtgtttca agctcgcgag ggagtttctc gcggtcactt gatcgttcgc ttgcccatag
      421 ttgtatttgc cttccaccag cagccgctgc cgatgtgcgt agagtgtcag tcgggcggcg
      481 ctgttgaagg ccttggtact gctgttgcct gacgtgttgt tccctcccac cgagacggtg
      541 cctgctaccc ggaagggctc aaggttaata gcggtgatat ccgacagcgg cgtggacgta
      601 tcctggcctg cttcagagac ttcgcgttgg ccctgcgtgc cgtagacgaa atcgcgaagg
      661 acatcccgcg attccccggg aaccagaatt ttgatcgggc ttgtcgctgt gaggcgctgg
      721 acctttttcc aatcgacctt aatttcgccg ccatagtccg tttgaatcgt caggagattt
      781 tcttccatct tgacgatcgt gccggtgagt cggtcgccgt tgagtaaata aatttcatca
      841 gcagccgccg gcgtggcaag ccacaaacta aagagaagca acgcccgctg ccagagcagg
      901 agactgaaga catggcgatg gtgcatggat gtaaaccgga actcagacgg gcggcggctc
      961 gaagtcgagg cgaggtgctg ccatctgtag accaggtctc accctaatcg agaggagaag
     1021 aagtttcaag tgcacgtgcg agaaagtgat ctggcgtcaa ccagcgggcg gagattattt
     1081 cgcgatggtg atgctgggca cgccgcttcg tgacacttcc gtgacggtca tctggaacag
     1141 ttggtagagc agcttgaagg cttcacggtt ccatcgagcc agtgggccgg tgatgttgac
     1201 ggagtaatac ttgccatggg actgcacggt gagatccgat tcggacgggc tggactcttg
     1261 taccaggagg tccatggttt tgactggatt gtccataaaa ggcggcgtgc ggttatcttt
     1321 ctcgaccgcg tattccggtt cttcttccac ggattgcgcc agaaaattga gcatggtgtt
     1381 gaagctgcgc agacggaatt cgcccttcag cggccactct ccgccataat gtcccggacg
     1441 aatgtcgaac gacacatcgt tcatggggct tcgttcagct tcctcgtgca gccggacccg
     1501 ttcctcttgc ggaagtgtgt tgggatcgta gttcgtgatg agaattctgc cggacaccgg
     1561 tttacgcagc cggtaggttt tttgctgcgg atcgtaggca accagatagt cttgctccag
     1621 tgctttgaac ccctctgccg tcacggattc ggcgggaata gtccacgtgc gttcgaacag
     1681 catcgattct gcatagaggc gattggcatc ctgaatggcg gagaggtgca gcaccacttt
     1741 tcggaacatc tcatagcccg ccttatcggt cgggctattt cgataggcga tatcctctcc
     1801 ctgatcatcc acccgcagct cttttgccat cagacgaagc aggagatcga tatcgccgcc
     1861 ttgtcggagc aggagcgtga acttggtttc ttgaaagggt gtcagcaggc ggcgggtgaa
     1921 ttcttccccg tcgatcggtg caatgctgat agtgggattc tccgccacac tgccgccgaa
     1981 caccggcagc agcgttttgc cggcttctcc ggtcaaagta ggagtcgctc cggcgttgat
     2041 ccggaaatcg aaggtggccg cgacgtttga gacgcctgta aagtgaacgg gctgatggtg
     2101 atgggcgcgc gcgatattta acagcagctg tttcgaaatg gagtcggtga tggcgttatc
     2161 gtaggagacg actgcgcgcg tgagcgtcgg cggcgagaga cagccagcaa ggttcatgaa
     2221 gacggtaaga gcgatcaggc cacgcagcaa aagggatgga atggtcatag gcatcgagtt
     2281 cggtgatgaa ggtggcccat caacagcggt tctagcatac ctattccagg aagcctaggg
     2341 ggatggatgg gcatgtgttt cgccggacgg cgcgagctcg cctcggggcg gcgatttggt
     2401 ttatcatcgg gcactgtgat gaccaggaac agaatgagag ctcgacacat gaggcattcc
     2461 gtgtgggttg gggtgatgac gctgctgtgc ttcaccggat gcggcagttc ggcaaagctc
     2521 atttccgggc tgagcatcga agaattgaaa cccgtgccgg gtattctgtc gagtgccagg
     2581 cttttaaaag ggacgatccg cagtatcacc ggcgaccgtg tggaagtgga caccggcgaa
     2641 cgggcccccc gttatttgtc gctggaggcg ggcggtgatg aagcccgcgg gttgcaggtt
     2701 ggcggggcgg tggagattat ggtcaatgac catgatgaca tcgtcgcgta ccagcgaccg
     2761 gccgagacgc cgccgaccaa agtgtttcgc ggatctctgg gcaaggtgtt taatccgcaa
     2821 aaagaacgcg tcacgattcg tctcgatacc gggcgcgatg tggggttcta cgcgcggtcc
     2881 gtcgcgatgg agaaactcgc ggcgctggag gtgggagaaa cggccgattt tgcggtggat
     2941 cgcgcctatc tgctcgtgga tgtcttgtcg ctggggaagc ctcgcgacct gggagtcggg
     3001 tcttcgctgc ccgcgccaca acgtcgcgtg gaaggggcgt ttgttacgat cggcgacggc
     3061 cgcatgcggc tgaggatgaa gatcgacgac attcaatcct ttcccgtgcg tcccttgttg
     3121 cagccggcca tcgagcaact gagcccgaat gagaccgtct cgatttacct cgacgggcag
     3181 gggcaggtga tcgatatggt acggacggcc cgccggtaag ctttgtcagc ggcgccgggg
     3241 aagcttcacg atacgggtaa tgatccaatc gttgaggcga tcgggcagga ggagtgccag
     3301 ccatgagcga atcgtggcat ctgagcccac caggtatcga gtatgtggcc agcgggaccg
     3361 cagcgcatgc gccaccgcct cagccaccac cttcgccggc tgagcctgtt cccctgctgc
     3421 tgtggccgcc tctttgatgc gggtgaaccc ttcctggtac atgtccttga ggtccggact
     3481 ccaggtcgca tcccaggtat cgacttcttt tctggtcttt ccccaaatgg gcgtggcaat
     3541 ggcgcctggc gtaatgaggg cgacgcggat gccccatggt tgcagttcaa ggcgcaacgc
     3601 atcggtgatc gcttccagcg catgtttgga ggcggcgtag ggggccatga acggcatgga
     3661 agctcgtccg gcgatggagc ccatgttgat gatgcgtccg tgacccgtgc ggatcaacgg
     3721 caaaaacgtc tgggtcaccg cgatcagtcc gaacacgttc acctcgaatt gccgtcgcca
     3781 atcggcgagg ggcaggagtt caatgggacc ggccacgccg atgccggcat tattcaccag
     3841 gcctgcaagg ccgcgatcgc ctaccatggc ggcgaccgta tggctcgcgg ctgcgatcga
     3901 cgcagagtcg gtgacatcnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnntc
     4021 agatgtatcc gatgacgtgc gagaggcgct gtgccttcgg cgtagaacaa gcaaacgctc
     4081 gagcgatgag aggagcaggc atgcacacag agaaatgcaa atgggcgctg ctgcttatga
     4141 tgggactgag cctggctgca tacgtgtctc ccctgaacgc aggcacggat cagaagggag
     4201 tcgtcgccac ggagaagctt gtcacggtgc agccgcggga aatcgacgac gtcttagaca
     4261 atcccgggat gggatttgcc gactttcact tcggcttcgg ccatcctccg aagcctgatg
     4321 aatatccaca tacgaccgtg gcctatttcc gttggccctg ggcagagctg gaaccggccg
     4381 agggccagta caattttgca ttggtggacg gagtcatcgc acaggcgaag gctaagggtg
     4441 agacgctcgc catccggatc gtctcagaat ataagaccgg caccccgcaa tggttgctgg
     4501 ataagggagt ggccagcatc aaagaaacgg acgggatttt ccccgactat aacaatccca
     4561 tcttcctcga ctaccacgaa cgtctcatcc gcgcgttcgg cgagcggtat ggccggtcgc
     4621 tcgacatcga tcatgtggat atcggatctg tcgggtgttg gggggaatgg aatacggcgt
     4681 gctgtgtagg agcagagacg cagtgtaagg cctactaccc aactgaagcg aatcagctcg
     4741 ccattaccga ttggtatctt aaatatttct ccggaactcc ccttgtgatg cttcacggag
     4801 gacaattgca atatgcggcc tcgcgagggg ccggttggcg ggctgattgc ttcggtgact
     4861 acggctattt ctctcccgac tggaaccaca tggagcatgc ctatgcccca gtcctggagg
     4921 cgcaggtagt ggccgatgcg tggaaacagg ggccggtaca gatggaagtc tgcggctata
     4981 tccatgaatg gtacgaacgg ggcttcgatc tcgaccgcat cctcgagaag gggttggaat
     5041 ggcatgtctc ggtgttgaac gccaagtcaa aaccggtacc cgccgcctgg cggccgcgct
     5101 tcaatgagtt tctgaaaaaa atcgggtatc gatttgtgct gcgtgagctg acccacccgg
     5161 cctcgatcgg agccggtgaa tcgctcatca ttcactcacg gtgggacaat aaaggggtgg
     5221 cgcccatcta ccatgcctgg ccgctggcgt accggttgcg ttcgggcacg gatgaagtgg
     5281 tcgcgcagtg gaccagcgct gccgatctga agcggtggct gccggggcct tcgcacctgg
     5341 ctgaggatgc ggtggtggtg ccgagcaccg ttcctgccgg cgtctatacg ctcgatgtcg
     5401 gaattttatc tgaggatgcg aagtctgcga cggtcgagtt agcgatagaa ggcaaacgga
     5461 ccgaccgctg gtacgccgtg tcgcgcgtgg agattcgata ggctgtcggc cgtcgtgcag
     5521 atgggttgat ctgggaagag ctgaggatgc ggaacggcga cttgggctcg acctgcatct
     5581 ctagacagcc agggccgggg ccgccgcctg ctcgaggcgg agtaccgtca tcacctggtt
     5641 gccgttgccg cggtattcga tctgatcgaa gctgactttg ttggccatgg cgattcctcg
     5701 tccgtgggta tcaaaggcgc gctcgggatc gaagtccatg tatctttgcc aatcaaaccc
     5761 gtttccctga tcggtgatgt gcagcgacag cccctgcgga aggcgagaaa attttgccgt
     5821 ggcgacacgc gacgagtagg ggggcgagct gagccgatga gcgatttctt cttccagctt
     5881 atcttcttcg atgaggcgtg acttttcctt atacccgatg ctcaggttgc cgtgttcgat
     5941 cgcgttcaag gtcagttcga ggatgccggt gacgacgcgg tcggcatcgg gataggcatg
     6001 cgcgagcaac atggcgaggt ttcgtgcttc ttcgggcgtt ctaaagtgga atgtccccga
     6061 ctccaacagg cgcatggtcg tcgtagtccg gcgcagatcc tgccggatgt ccagatagct
     6121 gatgtggtcg cggaccgcgg catccacaat ggcctgaagc gtcgcctggt cgaacggtgt
     6181 ggctagataa tagtaggccc cggcctgcag tccctccagg gtctgctgat gtgtcgaggc
     6241 ggcagtctgc atgatgacgg gaatctggtt cagtgcatca tgttgcttca tcttgtggag
     6301 gacttccatc ccatccatcc cgggcatgat gcggtcgagg agcacggcgt ggaagcgatc
     6361 gggctcagct tccagcatat cccaggcttg ccggccgtct tgggctgtgg tgcagcgata
     6421 ttgacgttcg ggaagaaact ctctcagaat tttgaggttc agagtcgagt catcgaccag
     6481 taacagttgc ggttgaggga aaatcataat atggagcacc tccgcttggc ggccaagccg
     6541 tcggaagaaa aagcatagag tctggcctca catcgcagaa caaggccgtg atatgtctat
     6601 cggaagtctc tgaagaatac ttaagtgaag aaggaaggaa tatcgcgatg gactccgccg
     6661 gggtctaacc ccaggcggag tcatcagaga ggtctattgc ttcacgatat caagcagttc
     6721 cacttcaaac accagggtgg cgcctggctt gatcaccggg ggtgacccac ggtcgccgta
     6781 ggcgatgccg gacgggcaga ccagcttgct cttgccgccg accttaatca actgtaccgc
     6841 ttcggtccaa cacttgatga cctggttgag cggaaacgtg gccggttctc cacgcttgac
     6901 ggagctgtcg aagacggttc catcggtcag ggtgccatgg taatggactt tgaccgtatc
     6961 cgtggctttg ggggtcgcgc cttttccttc cttgatcgtg gtcacaatgg cgccggattc
     7021 tgtctttttg gcacctggct ccgctgcggc cttggccagg aatgcggctc cggctttttt
     7081 ctcgacatcg gccagggcat tggaccggac ctgctgcatc tgctgaatct tgggcccgta
     7141 cacgttcatg tccaccttct gtgaccgctt cagcacccca tcggcgatgc ccgacttgac
     7201 gaactcaagt tcggcttcgt tcaacgtaaa gggcgtgagt gattggctga tggcgacacc
     7261 gagggcatac agcgtttttt gctcgtcgtt ggccggttcg gaggcggccg cccaactgag
     7321 cgaggagatg agaagcacca ctgcggaaac ggcaccagtc acatgacgca tagacgatcc
     7381 tttctgctga aacagcatga ctgagcccac catatgacag gcagcgtatg cggctcaaga
     7441 taattcttgg gcaggcggct gaaatcgacc tcccgcgtcg ttctcggctc gtcaaaatcc
     7501 gcaacgtacc cctgcgggta cgcctccggt tttgactcgc ctgcggcctt gcgggacgtc
     7561 gttttgagca gcctgtgagg atcgcgcgaa ctcgtttgag gccgtcctta cagaagattt
     7621 gtccgaggta cagatgcggc cgacgtcgct tgattgagca ggctgtcgtc aagtgaggct
     7681 caggagaact tgtctcgtcc gtgagggctc tcaagatcca gttgcggtcc gatgggcacg
     7741 atctgggtcg ggttgatgtc atcatgcgtg acatagtaat gccgcttgat atgatccaaa
     7801 ttcaccgtgt ccgcgatgcc gggtacctga tagaggtctt tgaggtagcc ggagagatgg
     7861 ggatagtcga tgatgcgccg gacattgcac ttgaagtgtc cgtgatagac ggcgtcgaag
     7921 cggatgaggg tgacaaacag tcgccagtca gattccagga attgcgggcc gaagagatag
     7981 cggcgttggc tgagtctggt gtccaattga tccagggcag caaagagcga ccgtgccgct
     8041 tgttcgtacc ctcgctgaga agtcgcgaat cccgccttgt acaccccgtt gttcacctgc
     8101 tcatacagga atgtgttcat ctcatcgatg tctgcgcgca gcgctgcagg atagagatcc
     8161 agcgtactga tggtgaagcg gttgaactcc gcgttgaaca tccgcatgag atcgtcatcc
     8221 gaattgctca cgattcgctt cgtgacggta tcccacagga ccgggacagt gacgcggctt
     8281 ctgtaggtgg ggtcggtcag gtgataggcc tcgctgagga agtgaaatcc attgatggga
     8341 tcgatggagt ggccctggcc ggtacgaaac gcccagccct gttcgtcgcg aatgggatcc
     8401 accacggtca tgccgacgac cgactccaac tgtttgagtg cgcggacaat gatcgtgcga
     8461 tgggcccagg gacaggcaag ggacacatag agatgatagc gcccggctgc ggccggcaac
     8521 cctgatcgtc cgtcgtcagt cacccattgg cgaaaggcgt cttcttgccg ttgaaattcg
     8581 cctgactcgg tgtgttcgtt tggaaactgc ggctgtgggg tcatgcttga ttctccttga
     8641 gcgttcgacc ttagtcagat ccgatgagtg ccgtcaatcc gggatcgtca agagacgtga
     8701 gtcgcacggc agcgacggtt tattttcgac caggcgggga aacctggtgg ggcgctgaaa
     8761 gatcccatcc gaccgaaaag agcacgagaa gcccggcgcc ggtcgtgtgc ttggtacggg
     8821 cgctggtctc ccgcgggggc aacggctcgt tggcgacaag cccgtctccc agaacctgcg
     8881 tatccagatc caggatgccg ccgataccga aattgaaact gtactgatcg ctgcgatgcg
     8941 gccggtagcc caccatgagc ccgcctccca cggcgtcgat gatccgggat cccggagcca
     9001 cggccagaaa tggtccccaa ctccatcgtt gctcatccca gcgatcgatc cagaggtgaa
     9061 cttcgggcat cgcgcgaacc aggtcgttgc gttcgtcgtc gatgcgtacg atgcggttgg
     9121 tgacggaaac ggattcgact cgccgcgcgc cgagattatg agtccatccc agaccgagcc
     9181 caaatcccac gttctgaaag agcgatgggt gtggagggtc ttccgccact ggctcaggct
     9241 cctcctgacg gccgtagagg ctcggtgacg actgccgaag cgtgggcgaa ctgcctgtct
     9301 ccgtggcttg ggatggagga gtctgaggaa gggcgggatg gtcaggtttg ttttcaactg
     9361 gtgatgtgga tagggcgaga gcagccggcg cagatgtccc ctcacgctct gtcggctggg
     9421 agacgcgctc gcgatgatct ctgacggatg gaggcgacac gattgtgacg gcagagtctg
     9481 cggttgtcac cgttggcgac ggatcggttc gtcctgtgct gtcactgtca ctctggcgct
     9541 tctcaggcgg gactgatgag gagagaggct gaatcggttc cgggatggtc gttggaggtt
     9601 tgtccgaaac ctgttgggtg gctggctgca atgcatgtgg agggggcgac tcacggtttg
     9661 gtggcacggg cggctccgcg gcggtcggtt ctgcggccgg tatcgagtga gtatcagttg
     9721 aaggtgggtt tggcgacgca agtggtgccg tagaggttct gaccggcgct gatgtctctc
     9781 cagggtgccc gcctgctacg ggcagagata cgccacccgc atcagcgctc gcgtccggcc
     9841 tgtgctctgg taaacgggtg gagggggatc cagccggagt gggcgcctcg ggtgaactct
     9901 gtgccggtag cgtgacagcc ggcgcctccc tgggctgatg cggaggcaag gagaatacgc
     9961 tgacctcagc gggactgaga accgcgctcg aattggggtg gggaggtgct gctgtgaggg
    10021 gctgacttga atctccagat tcctctccag ctgcccggcg aggtgttggc gtgtcggtag
    10081 ccggtgtcgt gtcaacagat gccgtcctga acgcctgttg gagggtggca ttatcactct
    10141 ccttggccaa cacgaccgga gttctcccat tggtgtcctg actttgagga tcggctccgg
    10201 agcgaagcag ccggtggatc acggcggttt gtcgagacaa tctatccgca tgggattccc
    10261 cgttcatctc ccagaagcgt cggaccgctt ggtggagcgg cgtgaatccc agttcgttac
    10321 ggatggtggt ctgcgcacct gcggtcagga gtgcttcgac gcatggcaaa tgactttgga
    10381 agctggcttc gtgaaggggg gtgtttccgt catggtcttg tgccgctact tgcgcccctt
    10441 ggctcaagag taaaaggacg agcggaaggt tgcctcttcc cgctgcggta atgagcggcg
    10501 tggctccttt agcgttgcga gcttcgatat tggctccgcg gtcgagcagc acctgggtcc
    10561 tggttgtcga actttcggtg agagcggtat gaatggactg ttctgagcca acttgtgctg
    10621 cgactggttt cgcccgtttc tcgacggggc gagcatcact gacggacgag tatccgacga
    10681 ccaggagaag aatggcgctg gcaacgccgg tgctgtggtg caagcgaccc acgggtaccc
    10741 aaaaaagacg agtcggaaga ttgcaatgcg gactgtatgg tttagcatac agctcagtcc
    10801 tgcgtcatcc gccgttgtga ggtgaatgag aagaagggaa gatcgaacca cagcgaagtg
    10861 gatgaacccg taggtgcacc acggctgcgg gtcgagagtg gcgagacggc ctaccagcgg
    10921 cgatgccacc gtccgtaata gggacggtaa taacgcggtc cccaggcata ggggcgtgcg
    10981 taaaacggag agccgtaaat ccaggggcgc ccgagataca ggccgaagcc gacggacggg
    11041 tatccgtaca gcaatcctgg cgcgattccg ggggacacgt atccataagt cgatggggcg
    11101 gacgattgtt gagacatctg ccgctgcaat tcagccgtca tggcgttttg ccggtcggct
    11161 tgatctttca actgtccgac ggtgctttgc tggagctgga cttccgcttc cagtttggag
    11221 attttttcgc gctggatttc aatgaaggcc tgcaggcatc gagtgtgcgc atcacccgtg
    11281 tagttggagc attcccaggg accggatgat tctgcagcaa acaccggaag ggcaaacaac
    11341 aggacactgc atcccattgc gagagaggtc caccattgcc gaggggattc caatcggtgt
    11401 gtcgtaagac gtaccataac gctcctccct ggctagctat tcacagccta tcatggctgt
    11461 gccggtgaag accagatccg gctcgtagag agtgaaacgg acgactgcct cgttggttga
    11521 cagagaggtg cgggaaagtg tgcttgcccg tgaccacgag agacgcaaaa ggagaacaga
    11581 acatgggaga aaagcaggta attgcggtgg tgggagcgac tggcatgcaa ggtggcggat
    11641 tggtgcgggc gatattggcc aatccagcca gcgggctggc ggtgcgcgcg ttgaccaggg
    11701 atgtcaattc agacaaggcc aaagaacttg cccggctcgg cgcggaagtg gtggctgccg
    11761 atgtgcatga cgtcgaaagc ctgaagcgag ccttttcggg tgccgccggt gcgttttgcg
    11821 tcacgttttt ctgggcgcat ttgtctcccg aaaaggagta cgccgaggcc gaagccatgg
    11881 ccaaagccgc caaggcagcg ggggtgcggc atgtgatctg gtcgactctc gaagatacgc
    11941 gtcgatgggt tccgctctca gacaaccgga tgccgacgtt gatgggcaag tataaggtgc
    12001 cgcatttcga tgccaagggg gaagcggatc agctgttcaa gcagcttggt ctgcccacga
    12061 ccttcctact cacctccttt tactgggaca acctcattca tttcggcatg ggtccgaagc
    12121 ctggtccgga tggagcgctg gcatttaccc tccccatggg tgaagcccga ttgcctggga
    12181 ttgcggctga cgacatcgga aagtgtgcgt tgggaatttt caagaagcgg gaggcctatc
    12241 tcggtaagac tgtcggtatc gcaggcgaac atctcaccgg ctcacaaatg gccacggcat
    12301 taggtaaggc gctcgggcgc gaggtgcgct ataacgcggt gccgccggaa gtgtaccgga
    12361 acttcgggtt tccgggggcg gacgacctag ccaatatgtt tcagtttaaa cgcgacttca
    12421 atgcggtctt ttgcgcagcc cgtgaaccgg cgattgcccg ggcgctcaat ggcggattgc
    12481 agacatttgc gcagtggctg gaggtcaaca aggcacgcat tcccctctcg taacgaaggg
    12541 acggtgaccg gcccgaaaac ttagtgctga gacttctgcc gggacagttg gcaggaggag
    12601 gtgaacggat tgcaccgcag ccggtgaatc ttgatcgtcc gcaacttctc cggtcctgcc
    12661 gtaatccgtg gctccggatg acgctcgccg ttcgtgagta ccggaaacga ggccagtgtc
    12721 gtcaggatac agatggacag gacggccagc acccaagcga agtagagtga gtaacgcatg
    12781 gcctattcgt atcatggtgg gattggaagt caatgaaatg gtcgtttttc gccatcgctg
    12841 ttcgttgatg atagttgcat gacgctgtcg tccatacgat ttcgccagcg ctgtaggccg
    12901 tgctccttcc cgccattgcg caagtggcgt gctgtcgcta caatcccctc gcttgccgcc
    12961 accggcggat gtcgtctcac cgacaggctc atagccgcat gctcctctcc ttcgtgattt
    13021 tgtatcttgc ctgctcggtc gggatcgggc tgtatgccgc gactcgcgtt cataacacca
    13081 aggactttgc cgtcgctggc cgctctctgc ctctaccggt ggtaacggcc acggtctttg
    13141 cgacctggtt cggggcggaa accgtgctcg gcatttccgc caccttcgtc aaggacgggc
    13201 tccgtgcagt cgtcgccgat ccattcggat cgagtctctg cttgattctg gccggcttgt
    13261 ggtttgcccg ccgactctat cgattaaatc tcctcacgat cggagatttt taccggctgc
    13321 ggtacaaccg cgcagttgaa gtgctgtgca cgctctgcat tgtcgcttcg tatctcgggt
    13381 gggtttcggc ccagatcaag gcattggggc ttgtattcaa cgtcgtcacg gatggagcca
    13441 tgagccagtc tgccggcatg atgttggggg cagtgatcgt attgacgtac acgacgttcg
    13501 gtggaatgtt ctcagtggcg attcttgatt tcgtgcagat caccatcatc atgggcggca
    13561 tgctctacat cgggtcggtg atcagcggcc tggcaggtgg agtagggacg gtcgtcactc
    13621 atgcagccga ggcgggcaaa ttggattttt ttccgcctgc acagatcgag gcgtggatcc
    13681 cgttcgtagg cgcctgggtc accatgatgt tcggatccat tcctcagcag gatgtgtttc
    13741 agcggattac gtcggccagg aatgaggaca ccgcggtgcg gggatccgtg ctcggcggaa
    13801 cgctgtattt tgtcttcgcc ttcgtcccga tgtttctggc ctattcagcg acactgatcg
    13861 atccggcgca ggtggccggt ttgctggagc gggattccca actcattctc ccgactctga
    13921 tcgtgcaaca cacgccgatg gcggcacaga ttattttttt cggcgctttg ctgtccgcga
    13981 tcatgagttg ttcatcggcc acgctgctcg ccccgtcagt ggccttcagc gagaatatcg
    14041 tcaagagctt aatgccaacc atcagcgatc ggggcctgct ggccgtgatg cgctcggtgc
    14101 tggtcggatt tactgcactc gtcttgctgt tcgcgctgaa ctcggaagcc agcattttta
    14161 agatggtgga aagcgcgtac aaagtgacgc tcgtggcagc ctttgtgccg ctcctggcgg
    14221 gcttgtattg gccgcgcgcg accacgcaag gagcgatctg cgccattgtc accgggctcg
    14281 cgacgtggct gatgttggaa gggacagtca cgccggatca ggtctggccg ccgcagttag
    14341 tcggagcctt aatggccgca ggtggaatgg tgattggatc gctgctgcct cagtggatta
    14401 cacatccggc gaccatcgac gtcccggtcg ggcatcggtc tcacagtatg ccggtggagt
    14461 cgcacaccgg gactcatccg tcgccctagg ctggggagac ggagtgcagg atctcgcgca
    14521 cgaggcggat caagtcttcc ggtgagaatg gcttctgcaa aaaggttgtc tgtccctgac
    14581 tctcgccgcc cgtaaccggc aggttgtcgc tgtaccccga catatagagc accttcaaat
    14641 cgtcgaagtg gcttcgcagc cgcatggcga gctccttgcc gttcatgccc ggcatcacca
    14701 ggtcagtgat caatagatcg atgtgcagat tattgcgccg gatgagatcc atcgcctgga
    14761 acccgtcctc cgcttcatgc acggtatagc catgcgtgcg aagaatgtgc tgagtcagca
    14821 agcggaccga cggctcgtct tccacgagaa gaataatttc tgtccctgnn nnnnnnnnnn
    14881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14941 nnnnnnnnnn nnnnnnnnnn nnnnnnnngc caatcgaccg accgcttcca ttttttgcgc
    15001 ctgccgcaat tggtcttcca gttcgcgagc atccgtaata tcttccgtaa tgccgctcag
    15061 gctatccacc tcgcccgtgt cggtgcgatg aatcaccatg cgatcgtgaa tccaccgggt
    15121 ttgcccgtcg ggtcgtatga tgcgatacag caattgcacg tcccgtccgg tgggccgggt
    15181 cagttccgtg tcatacacct cggtcaccat ccgttggtcg tccggatgca cgcaatcgcg
    15241 ccaaagtttg gggttctcat aaaatctggc ggccggcagt ccccagattc gctcgaaggc
    15301 cgggttcacg taaaggactt gaggcggctg cgcttgggca aaccacacgc cctggttcag
    15361 attgtcggtg aggtaattga accgtttttc gctcgagagc cgggcccctt ccgtccgccg
    15421 atgttcccgt acctcatcct gcagccggct gttggcatgg gccaggtcgg ccgtgcgttc
    15481 ggcgatgcga tgttcaaggt cgctctgggc cgttcgtaat tgctcttcga tcacacggcg
    15541 atcatgtatc tctttggtga tgtcccggtt caaacgttcc acggcttcgg agcgcgtggt
    15601 gagcgactgt accaggctga gtttctccag ctgcagccgc agggaggaga gcagcacatg
    15661 gttgaaggtc caggacgagt ggatcgtagc caggagaaac aacgtcccca tcacgcccat
    15721 gatcacatga aagtcataac cgctgaagaa gagatgcccg agtgtgggaa gggtgaccgg
    15781 cagcgcgtag cataagaaga gttggaatga gacggacagg accgagaccg ctccggccgt
    15841 catgccaccg agcacgaaca actgcaccaa ttcgtaggcg agggggattt ccggcgtcag
    15901 aaaatagaca ctgcctcccc agccgacgcc ggccatggtg gtcgcgacca gcatccagcg
    15961 atgccagtcg gcgctgctcc acgtggcagg agtcgttcga cgatagttgt agatgaggag
    16021 cgccctggca ccggcaacta tccagaggat ggctacccag acgagaagtg gcgtgtgcgg
    16081 gaccacgctc cattccactg cggcaagaat ggcggcgttg acagcgctcg ctagcacgcc
    16141 cgtgggcatg ttgcggtaca gaacagagac ttgttgtgat tggagttcca gtgccggatc
    16201 ggtgtgggcc gggcgatcca tgggaggacc tcgctcgata acagatgcgt cctgcacgcg
    16261 gtacccgtta gacggcgacg atccgcacgc gccgtcggat agcgtactct agcacgatcg
    16321 atgacaaggc gggcatcaaa aattcacacg gagattcagt gatccgacgt gcaaggtggt
    16381 gcgataggtt ccattgacgg tcggattcac gttgccggca acggtcctgg attcatacaa
    16441 aatggcctgg taagcgagat cgatgccgag tcccttgggg ctgagtttgc tcgcccctcc
    16501 gcagggtatc accccaagaa accgtccgtt gtcccgacac atgaacccga cgccggtaga
    16561 caccgcatgg ttgtcgccgt cggggatggc ggggttgaag gtttgatcgg ggatcgcctt
    16621 ttgtgaatgc cagtacccgg cgcggagggc gatatcccaa tcgggaagcg atgccgggtt
    16681 gagccacttg tgttccgtgc cgatcatgac ggtgtaaccg ctgatccaat tggccggagt
    16741 ggcgaccgtg atgccgtttg aaagatgtga atccaggtta cgaactgatt tccaccccgt
    16801 atagtccaca tccagttcca gtttccattc gcgttcttta ttgcggacag gccagagggc
    16861 gatgcctccc gtcaggacct gtggcactac gaaggtcgtg cgtgcgtccg cgatatgtgt
    16921 gccgccggcc agcaattggc cgtcgaggtg cagggtggcc tggctgcgat agataaggcc
    16981 gatgttgacg aggggtttgc catcttcatt gcgcagcggg gtatacagca ggctggcatt
    17041 ccagccggca gcggtgtcgc gtccgtttaa ctccatgccg gtgccggctg gaatgccgag
    17101 cccgcctggc cagcgaaatt gccgttcgac ctgtccttct ccgaaggctc ctgaaaacgt
    17161 atacacatcc gctcccagtc cgatggcgag gtccggaagc ggtctgaaag cgatggacgg
    17221 acgaatgtcg atcaactcaa aggcggcctt cgtggtggcc gtcgaaaagg ggctgctgtc
    17281 cggccagcga gtcaaggtgc cgaaggggct gaagacggcc agcccgaccg cagtgctgtc
    17341 ggaagagccg atgcccaagt ccttgagatt ggccgtaata tacagattgg acggcggcgg
    17401 aaccgccacg ctgccgcgga ggtctccatt ggcctgcgtt cctgctccgt tctgaaagga
    17461 aaaaccaccg gcgatcagcg tggtgccggc tgaaagctgc acaccccgca actgtgtcat
    17521 gccggcgggg ttgtaatagc cggcggaggc atcgtcggcc tgagctgtga acgcagaggc
    17581 ttgaccggtc gccgaggcgc tatggtcata gatgcggaaa cttccggcga gaaccgagcc
    17641 cggagcaatg gtcgaccagg cggccagcag cgcgccggtg aggaggagca ggcgcgcagt
    17701 ggtgcggccc ttccgacctg gagcgaccgt ttcccggctt gctgtcggcg ggtcggtctc
    17761 ggatgaagca ggggccgtga agaagcgcat catactcacc ggtcattcct catatagttc
    17821 taggtacaag atcgtagcca tatggtcttg tgcggctcat ctaagagaag gacgggcatt
    17881 ttgtcaagca ggggcaagcc agaccgattg ctggaagccg cggcgaatgt gtttttatgc
    17941 gcgggatcgc gtatgctcgg cggcatgagg attcggtggt gagattcgta aggcggtggc
    18001 ttctccgcgc gcttgtggcg gtgacaggca ttctccttct cgtcctcggg agcgccctgg
    18061 cttatggact gtacctttct gccagccttg cgttgccggc aggagatgaa catcctccac
    18121 gcctcatcta tggcgcgccc tttctattaa agcccgactt ggatgtggtc tcctcgcatt
    18181 tgatcgagcg cctgagccga ctgggttatc aggcggtcga cacgcccgtg cgcgcaccgg
    18241 gagagtttcg cgtgagtccc ggccagattg atatctatct gcacgaattt tccgacttgc
    18301 atctgcggcc gatgccggcc cgtttgctgt tggagcaggg acgtgtgacg cgggtcctgt
    18361 cgatccagac cggcgacgaa ctctttcccg cctatctgga gcctcagttg atcagcggac
    18421 tgcgcggggc atcgcggcag gtacgggaat gggtgtcgta tgacgacctc tctgcgcgat
    18481 tcctcgatat cctgctcgcc atcgaagacc ggcggttctt cagccatccc ggcatcgatc
    18541 cgatcgccgt gggacgggca gtgtggacga atgtcaccaa gggaacggtt attcaaggcg
    18601 gcagcacgat cacgcagcaa ttggccaaga acctgtttta ctccccgcag cggacgttcg
    18661 ggcgaaagct gaaggaatcc atcgccgcct tggtgttgga gacgaaatac cccaaaaaag
    18721 ccattctcga aagttatgcc aacgagatct atctcgggca ggtcggttcg gtgtcgatct
    18781 acggcgtcgg cgaagcagcc caccggtatt tcggcaaacg ggtggatacc ctcagtctgg
    18841 aagaggcggc gttgctggta ggcatgatta aaggaccgaa tacctattcg cccttgagaa
    18901 atgccgcctt ggccaagcaa cgtcgcgatg tggtgctggg ccggctgcat gaacagggcc
    18961 tgatcaatga cgaggcctgg gctcaggcga tcaagacgcc ggtgcannnn nnnnnnnnnn
    19021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19081 nnnnnnnnnn nnnnnnnnnn nnnnnnaaaa ccggcggcat cctggcgatg gtgggcagtc
    19141 gcgattatcg tacgagccag ttcaatcggg cggtgcaggc gaagcgccag ccaggctcgc
    19201 tcttcaagcc gctggtgtat ctcgccgcca tggaggcgcg tcgtgaactg aatggcgggc
    19261 aaccggtaac ggcggctacc tcgatcgtcg atgagccggt gacgtttgaa tcggccacgg
    19321 gccggtggac gcctcagaat tacgaccata aatttcacgg gacggtgtcc ctgcgaacgg
    19381 cgttggaaca gtcactcaat attccggcgg tcaagatcgc gcagctcgtc gggacgaaac
    19441 gcattctttc cctggcagag aaactcggta tccggagtcc gctggccgat aatctttcca
    19501 tcgctctcgg gacctccggc gtgtctctcc tggagatgac ttcggcattc ggcgtcctgg
    19561 cccatgacgg ggtcagcatg actcccacgg cgctgcaggc ggtaatgacc tcggagggag
    19621 atccggcctg gcatcacacg ccggctaggc atcaggcggt gtcacctcaa gcggcgtatg
    19681 tcatgacgtc gttgctcaag ggcgtggtgg aacgcggaac tgcggcgaag gccaaagcga
    19741 tgggcctgcg cgggattgtg gccggcaaga caggaacaac ggacggctat cgcgacgcct
    19801 ggtttatcgg ctatacgccg gatgtggtcg taggggcatg ggtgggattc gatgatgagg
    19861 acgcgttgca cctgaccggc gcacaggccg cattaccgat gtgggtggag tttgtgcgcc
    19921 agattctgcc ggctgcaccg cgtgactttg tcatgccgcc agccgtgatc acgcgtgaca
    19981 tcgacccgca gtcctcgcag ttggccacct cgaaatgtcc gcaacgttcg gcggagctgt
    20041 ttatcgaagg cacggagccc tcggtgtatt gcgaagtgca cggaagcggc atgtgggaac
    20101 gggtgaagcg gagttttggt tttttctagg tgtcatcgaa aagctggtgt aggctcggct
    20161 catgttgaat tggttctccg gttcatccgc cactgcccgc gacaaggagc tcccgatgat
    20221 gaagaaaccc ggctttgtgg aaagcgacaa tatcaccctg ctggccaaag gcgtgttgct
    20281 caggggagaa atccatgttg aaggcacggt gcgcatcgac ggccggctgg agggagattt
    20341 gaagaccagc gggacggtgg tgatcggcga agacggagtc gtgcagggca ccatcacggc
    20401 cggcaccatt atcagcagcg gaaaaatcaa agccacggtc cgggccacgg aacggattca
    20461 attgttgaag acggggctcc tcgtcggcga ggtgcacgcg ccggcattct cgatggaaga
    20521 cggagcgaaa tttcagggcc tttcggatat gggcgtcacg tcgtggggcg atgacgcgca
    20581 gaagcttccc ggtaacgtac gggagattgc ctcccagcgt cccaaagcgg tggccatggc
    20641 cggggagaac gcctgaacgg cgtctctccc gacctcccgg ctatctgatt cggcttcttc
    20701 acgcttaccc ctccgtctca ttgctcagcg ataagtcttc cgtacaggca cgaggatcgc
    20761 aaaaccagcg cgtgacatca cgggcgggtt ctgctatcaa cggcgcaggt acaaacatct
    20821 ataccccctc atgaatcgac gacagatttt tgcagcctgc tttttcggcg tcctgctggc
    20881 gctgctgtat cagatggccc tcatgtttcg cccgtttgtc ttcccggtcc tgtgggcggt
    20941 cattctggcc cacctctgct tcccactcca tatccgattg acggcctggc tgggcgggaa
    21001 ggaatcgcat tccgccgtac tcctcacgct ggccgcgctg gccttggttg tggtgccgct
    21061 ggtcgtcctc agtgtgatgt tagtcaaaga ggccgggtcc gccgaacgtg cggtacggga
    21121 atggatcgcc tcgggaggcg ttcaacagct cccggatcgc ctctcgggac ttcccggtgg
    21181 aagcgtggca cgggagtggc tcgagcgatt cacggggcag gaaagtgacc tggagcaatt
    21241 tgtgttgtcg agtgccaaga cgttcagcaa atttatcgtc ggggaattga gtgacctcgt
    21301 gcgcgacgtg ttcatgctgg tggccgattt tctggtcatg gtgtttacac tgtttttttt
    21361 cttcaaagac ggccggcatt ggctcgcatc actgtacggg ctgattccgc tcgaggcttc
    21421 ccataaggac aagattctcg tccgtctgga ccaaaccatt cgtgccgtgg tcaaggggat
    21481 tgtgctgacg gctgtcgcgc agggactcct tgccggggcg gcctatgccg tgttgggtgt
    21541 gccttttccc atggtcttga tggcactgac cattctcctg gctcccttgc cgttcggcgg
    21601 cacggcgctc atctgggggc cggtggccgg ctatcttctg tggtccggga cggtgggaaa
    21661 gggcttagtg atgttggcct ggggcattgg tgtggtatcg accatcgatc agattctgaa
    21721 gccgctgttc atcggccagg gagcgcagat tcccgtcttg ctgctcacgt tcagcgtgct
    21781 cggtggattg gcagcctacg gcattctggg cctgtttctc gggccgattc tcgtcggatt
    21841 gttcctcacc gcgttgcaga tttaccgcga cgaataccaa ctgcagcccg cctcgccgat
    21901 cgtcaggtcc tgaccctcgt tgggcgcctc ttccctcagt cgagaggaat tgtaatggtc
    21961 atccctccga tcacatcatt gagtgcgaag tcccgtttgg ggctcagagg atgactattg
    22021 tgacacttga tgcaggcggc ggaaatcgcg cgatccgcat agaccgcttg gaaaaattgt
    22081 ttgcggccgc tggtgacaat gccggtgaac gggcgatcgg gtgtctgcgc gaaactctcc
    22141 agcgcctgcc gctccaaatc cgtcgccggc gcattgcgtt ggtaaatcgg ccagagactg
    22201 atcagccggt aacggatgcc gcgtccggat tcagcgacca gcttgcccga gtgttgcagg
    22261 aattgcgcgg gtaacgggag ggcgttttca tgctcccaat gttccatcgc ggagacgatg
    22321 cctttggcct gcatgcggtt gacgacctgg ttggtataaa tcgtccggtc ggcatcgagg
    22381 acggcatgga cgaagtccgc gaccttttcc ggggagatgc ctgccggtgg ggtgaggtcc
    22441 ttcgcctgca aggaataggt ggagacacaa gcgagaaaga gcgccatcca tatggtccat
    22501 gatcgtacac ctgtcaggtt gaaatgcatg gctcctcctt tcgtaccgcc gccttctctg
    22561 ccggcagcgt aatgacgcag gtggtgcctt ggccttccgg gggactctcc atccggattt
    22621 ctccgccgaa tttcttgatc aaccgctgcg cgacggtgag cccgaggccc gatccttcgc
    22681 cttgcccttt ggtcgtataa aacggatcaa agactttccc aagatgctgt ttgggaatgc
    22741 cgggtccgtt gtcacgaatc ttgatggtaa tcacatcgtc ctgctcttcc gtggtcagcc
    22801 acaaattgcc ttgcccgttc atcgcttgaa tggcattggt gagaacattg atgaaagcga
    22861 ggcggagctg gtcgggaagt gccgtcacgg gggatacagg gacataatgt ttttggacgt
    22921 tgagccccag gcattcgtgt gaggtctgca cgatagccag tgcctgttcc agttgagccg
    22981 tcacatcgac cggcatccgt tggctcttcg attcgcgagt cgccacaccg gtgaagtcgc
    23041 ggatgatggc ggccatcttc cggccgtgac ccacgatgtc ttgcgcgtag cctttggcgc
    23101 gggccagatc cccttcttcc tgaatggctt cgccaaggcc gagaatgccg aacaagggat
    23161 tgttgagttc gtggccgatg ccggcggtca gcacgtccaa gctgcctgat ttttcagcct
    23221 gaatcagctg atcctgcaag cggctctcat cggtcgtgtc ccggaggaca agcccgaatc
    23281 gttttcccgc gccgctgcgg ctttccagcg ggaaccactc atactgatac agatgcggac
    23341 cgatgcggag ctcgcgccgg gatgaagcag gggcgggacc gatcgtctga ttgagcggat
    23401 cgcgcgcggg cttcagcaag ggaggcgcgt cgtggcggac tggcgccagg gacatgcctt
    23461 cctcgaccgc ccggaagtcc cgctgcagcg cctggcgatg ctcctcgtcg acgggcaaga
    23521 ggtcgaacag cggtcgcgat gaccagctgt ccgcctgcac cgcctcacgc gacgccttat
    23581 tcatatattg gacgagccct tgttgatcca ccatgatgat aggcgttggc acggcatcga
    23641 gcacctgatc agtggctttt tggaggtact gtacttcctg cgttttttct tcgacctggg
    23701 tgctcaagcc ggcaaaggac gcttccaatt gtttgtgcat gcggttgaat tcgaccgcca
    23761 ggtcttccag ttcatcgccc gtgcgaatct ggatgggctc ctgcaattct ccgcggccga
    23821 tgaggcgggc cgcctcctgt aagcgacgga ccggcgtcac gatgcggcta gcggcaaaat
    23881 agcccagcgt ggcgagcagg aagagggcaa tcgaggccag gatcagcatc cacagcatga
    23941 gatgtcgaat tggtgagaac agttcgtcgg aggactgcca cacgaaggtg tgccacgccc
    24001 caacctccag ggcgccgttc gtggcgcgac tggtttcagg gagcaacgcg aacccgataa
    24061 tggccgtgcc ttgtccgcca tgcccatcgc tgtcggctgt gacccacccc ggttccctga
    24121 cggtcacttg cggaatgagc gccgggtctg atagccgaac gccggtgggc agaatgggac
    24181 agctcaacac gattcctcga ctgtcgatga gcatgacgtg gccggtcttg ccgaaccgga
    24241 tgggatgtgt cgagggagag aaaaattcct tggcatcgat gacgcgatgg aggacaccca
    24301 ccacttcata tttcaggctg tccatgatcg gtagcgaaat gctgaagaca taggctttgg
    24361 cctgttcatc gaagtgcaga tcttcgatgt acagctgccc cacccccttg ttgtaagttc
    24421 ctttccacca cggactgtcc gcattggaaa aactcgggaa ggtggtgagt gcagcgaaca
    24481 aattgccctg cacgtccgtg atgaacagct ttttcgtggc ggcgcgtacg acttgaggaa
    24541 gcagcaggtc ggactcattt tgagcccccg cgtaaaagct ccgcagcaga acggcggtgc
    24601 gattttcggt aatggccttg acggcaatgg gatcgcgcgc ggcccagcgg gttcgttgtt
    24661 gggtgatcgt cgtggcggac agagttttgt cggcggtctg cagcagatct cggtggtgct
    24721 ccagttgtcg gatgatctcc gggtgtgtgg cgatgcggga cgttctggcg acttcctcgg
    24781 ccacgagcaa gtccagtttg cgggcggctt ccgtggctaa ggcctggaag ctttcgccac
    24841 tgacgacttg gatttctttg gagccttgca ggaaggccat gctcaggccg agtagcaggg
    24901 gaaccacgcc gaccagcagc atcgagacga tgagcttacg tttcaggccc catcccagcg
    24961 gattggagaa ggggcgccag gtgatcgtca taggggcgcg catgatgtag tcggttgcac
    25021 ctgtggaaat tcgatccgga aggtcgtgcc gacaccgacg tcgctttcga cacaaatgtg
    25081 tccttccatt ttcgaaatca ccgacatcac attgtacagt cccagccccg tgcctttccc
    25141 cgggggtttc gtggtgtaca ggggctcaaa gattttcgag aacgcctcct tcggaatacc
    25201 gcaacccgta tcgctcaccg acgcgctgac ctgtccgtcc gggccaacgt tcgtgtgcag
    25261 ggtcaacgta ccgcggtcct gaatagcctg aacggcgttc gtaattaaat tgacgaagac
    25321 atgaagcaac tcgtcagggt tccctaagac cgaggcatcc tcagcatacc gtttcacgac
    25381 ggtgacatcc tgcagggtca cggcgtaacg ggcgattctc agcgcctcat ctaatttggt
    25441 gttgagattg accatgatgt cttcccccgt cccgttgcgt cgtgcatacc gggtgaggtc
    25501 gcggcaaata gcgctggtcc gtttcacggc ttcggtgatg tcgcgcgcct gttcgtgaac
    25561 gacggtcaaa tcttgctcgt ccgtgagatt ttccgcaagg ccgaggatga gctgaagcgg
    25621 gttattgatg tcatgcgcga tgcccgccgc aaaggaccct aatccagcca gtttatcggc
    25681 ctgaaacagt tcggcctcca gtttcgactg gtgctggacg agtttccata acagccgcgt
    25741 cgtggctccg ctcaagactt cggcgccggg acgtttcatg gcttggatga agggggccat
    25801 ggatggatca cccgtcacat ccatgatgag gttgacgcca tggttgcgaa tgaggtcgta
    25861 cacctgttcc tcaactggca cattcaaatc tttcgctcgt tgcaggccgg gcgcggcggg
    25921 gtccttgtcc gcgatgccca cgatgtctac gtcgggaatc tgatgcagga gctcgagcag
    25981 tgcggtgccg cctcgtcctg cgccgatgat ggctatcttt gtgctggtca gtgtcatgcc
    26041 tgactccggg tggagggacg aaaacccctg tggtacaggg cgtcgccgtc ggggaggtga
    26101 tcaaactctc cccgacggcg agtgctgaag acggatacgg caggggccct tgctagagct
    26161 gggcgagttc ccgttgctcc atagccctcg ccacggcggt gcgaagtttt tccccttcca
    26221 ccggtttcac caggtaatcg acgacgccac tgcgcaggaa ggaggtggcc atgtcagtgt
    26281 cgggaaaacc ggtcagcacg ataatcggga cgcgcggcca ttcctgttgg aagtaggcga
    26341 tggcttcaac cccgttgatc ttcggcatgc ggatgtcaca gatgagcacg tccagcagca
    26401 gccggttttc tccggtgttg atggcctcta tggctttttc cccgttttcc gcttcgatga
    26461 cctcgtagcc ggccttctgc agcgtcatgc ggacgacttt gcgaatgtcc ggttcgtcat
    26521 ccacgaccag cacccggcca ttgcaggcgg tttcactcat gaaaaagccc gatttgaatt
    26581 ctcccatgat cccctccttg gtggtgtgac gaggtgtaat gtcgtgaccc atttgttcat
    26641 aggctacagc aacagatgtg cctcgaaggg agagaggaag aatcactgaa tttcaggcag
    26701 ttagccgcta ttctccggag agagctgcag ggctggtggt tgggatccac cagccctggt
    26761 gaaatgcacc accgggatgc cctcgctaga ggagcccatt acggtaatag agtctgaccg
    26821 gtggtgccag tgaagaaagc ggttcgaatt cggacgggcg cctgctaacc gattatttgg
    26881 cgggcgggtt cccgaagaaa tgcaggtctt tctcccccct gagatgttgc ggcgtcacga
    26941 catattcccc gccgatagcc ggcccccaga ttttgtcggc cgtagccttg tctcccccgg
    27001 taaaaatgaa ccccattcct ccggcaacag ctccgagtac ggcgacggcc atcttgattc
    27061 cgccataggg taaggtcaga aaataacttc ccaggccttg aatggcttcc gatccggaac
    27121 cggccgccga agccgttctc accgagagcg tggcttggca tccgagcacc aggaccaaca
    27181 cgaacaaggt cgtttgtacg agcgggcgtg gctgtcgaga cttcgtctga gacatgagta
    27241 ctcctttctg cgtatgggca taacctaggc tacgtatcgt cgcgtagtgt agcgggccag
    27301 ctgacaaatt gccatctgtg gagcagctgg acgcatctca taattgactc agcgcctcac
    27361 attgccttcc gcttcccgga tgcgttattc tgctcacaga tgattaccgc cgaagccgta
    27421 acgacctata tccgtcaaat gtttcccgat gccgctgtca cggtgattga taagaccggt
    27481 acgcaggacc atttgattgt acgcgtgatc tctacgggat ttgccgataa gaatctcctg
    27541 gaccggcatc gcatggtcta tcaggcatta gcgggtccga tgaaagacgg gcgcatccat
    27601 gcgctggaga ttacggctat gacaccggat gaagtgaaaa aataaggggg accagatggc
    27661 tgacccgatt gaagaagaaa ttcagcgaga aattcaggcc aataaaatcc tgatctacgg
    27721 caagggcacc aaaaccatgc ccatgtgcgg gtttacccgg gagacgatgc atttttttga
    27781 aaagtacggg tatccctatg aactcatcga cgtcttatct cagcccgcca aacgcgaggc
    27841 cttgaccaag ttgacgaatt ggccgacctt gccgaaggtc ttcatcgacg gacagtttta
    27901 tggcgacacg gatatcctgg accccatgga agcgaagggg gaggtggtgc cgctgttgaa
    27961 aaaagccttc ggcgccgaat cgtaaggctt ttcgg
//
LOCUS       DAOQPD010000051        27903 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_779_length_27903_cov_21.450661, whole genome shotgun sequence.
ACCESSION   DAOQPD010000051 DAOQPD010000000
VERSION     DAOQPD010000051.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 27903)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 27903)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27903
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_779_length_27903_cov_21.450661"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(70..1551)
                     /locus_tag="PK063_12285"
     CDS             complement(70..1551)
                     /locus_tag="PK063_12285"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97876.1"
                     /translation="MPSISVLEQYDSNVFFTPKSQLAPGTKADDLITTITPQLNFMHN
                     TNLVKTNLSLGAVVQKFAHNSDLDNVGFNASGGVDLSQAVNRVLPRMKAFRIFGTYRY
                     SPSTPAFGVGGLGGGFGGGGGFGTGGVGISGPVDSGLLTQRIRTTMYSAGLADSYSLS
                     PTTDFQTTYTYSQLSFGGSFTPTSGTVGQASQTVFDTSTHSITAGPSSRITAIDTLTV
                     KYVFTQTSQPQFGEYTTHGGNVGWGRAWTKELSSSLNGGLTLIEPIPDSSAFGGQRRI
                     PATMFPTGGVSLTYASGSSFLRKLGSDFQEATGTGGASSMGGNFLPLLSGMNMPGGIA
                     SPGSYRITLLYNLGVFPSFVESAGPIYTHTVSLASSAGITDKLTAQALFNAARSSFTS
                     DAIGTTFTTYGTTVSLNYLITPTFTARLSHQWLMFDNQTSGLSAGDLGFSKHVILLGF
                     TYAYAPRGDFFRSGALWEGASGVSSSVDGGASKSGSGGVDTKK"
     gene            complement(1652..2275)
                     /locus_tag="PK063_12290"
     CDS             complement(1652..2275)
                     /locus_tag="PK063_12290"
                     /inference="COORDINATES: protein motif:HMM:NF014606.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015159 - polysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015774 - polysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis/export family
                     protein"
                     /protein_id="HMZ97877.1"
                     /translation="MKTFGCRWLRGGVCIVFSVLLTLPGCWIGNEQIDFNVTYIPPNE
                     FLLGPEDVLVVNVWRNQELSREVIIRPDGKISMPLVGDVQAAGMTSNVLAKRIADGLA
                     EFMSNPTVSVQVKEVNSYYVYVLGEVSKPGKVPLKSYATVLQGISLAGGFTTFASRNK
                     IHVLRVVPNGQGQPKQVQIPVPYEDILQGKNSEGNFFLKAGDVIVVP"
     gene            complement(2337..3038)
                     /locus_tag="PK063_12295"
     CDS             complement(2337..3038)
                     /locus_tag="PK063_12295"
                     /inference="COORDINATES: protein motif:HMM:NF014606.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_function: GO:0015159 - polysaccharide transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis/export family
                     protein"
                     /protein_id="HMZ97878.1"
                     /translation="MKAKVVLSLMVLAGNCLNVAFAGPFDQAPKATLVAGAPAAAPPS
                     GMRHGGDGAEKSSLTVTPDYIMGPEDVLEITVWKNADLSKQVQVRPDGRISLPLIGDV
                     SAVGRTAAQLTEEISARLKSYMENPTVSILVREVNSYQIYVLGEVNAPGKYPLKSKTT
                     LLQAITIAHGFTQVAARNKIVVFRFGKDGEGLNKIKASYDDIVLRDGSDQNIELKPGD
                     QIVVPSETMVVLPSR"
     gene            3516..4127
                     /locus_tag="PK063_12300"
     CDS             3516..4127
                     /locus_tag="PK063_12300"
                     /inference="COORDINATES: protein motif:HMM:NF012422.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="HMZ97879.1"
                     /translation="MAQIAITSQETADNLADQRTGAGIVVLSSSMQLLHMNRQAAELS
                     KLINMAEKGGTPAKAAQGVLPSALTELCTEILKALQVRTEAKDWEQFEVKKIAGNPNQ
                     PVLLRGFGLPDRGGVQYARLVVTLEELGRRQQLNTDQAKERFQLTNREQSVVENLAKG
                     WTNKEIANALKITEQTVKEHIKHIMRKTNSTTRTGVLVQIFKS"
     assembly_gap    4155..4254
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<4255..5183)
                     /gene="aepY"
                     /locus_tag="PK063_12305"
     CDS             complement(<4255..5183)
                     /gene="aepY"
                     /locus_tag="PK063_12305"
                     /EC_number="4.1.1.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033980 - phosphonopyruvate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonopyruvate decarboxylase"
                     /protein_id="HMZ97880.1"
                     /translation="MIDPRKFVECLQSNSVEFFTGVPDSLLKEFCACLEQVPQAGRHI
                     ISANEGGAVALALGYHLATGKVPLVYLQNSGLGNIINPLLSLADAEVYSIPLLLVIGW
                     RGETGVHDEPQHKKQGRVMLAMLDAMEIPYSILGPEVNEAEGALSDALAYVQKHNAPF
                     ALVIKKGTFGAFTGDKRKTEIFELTREAAIQQVLEHLDERDVVVSTTGMASREVYEYR
                     MNKGQGHERDFLTVGGMGHASQIALGVALQRPSRSVYCLDGDGAVLMHMGALPITGTL
                     KPENFKHIVFNNGAHDSVGGQPTVGLEIEILEIA"
     gene            complement(5292..6926)
                     /gene="aepX"
                     /locus_tag="PK063_12310"
     CDS             complement(5292..6926)
                     /gene="aepX"
                     /locus_tag="PK063_12310"
                     /EC_number="5.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050188 - phosphoenolpyruvate mutase
                     activity [Evidence IEA];
                     GO_process: GO:0019634 - organic phosphonate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate mutase"
                     /protein_id="HMZ97881.1"
                     /translation="MNSRQPLTKTRQFRNLLLSEQLEFICEAHNGLSAKIVEEAGFPG
                     IWASGLSISAQFGVRDNNEASWTQVLEDLEFMSDATNIPILLDGDTGYGNFNNMQRLI
                     RKLEQRNIAAVCIEDKLFPKTNSFLKGDAQPMADMHEFCGKIKAGKDAQTDPDFCVIA
                     RVEAFICGWGLTEALRRAEAYHQAGADGILIHSALSVPDEILAFKREWGNRCPVVIVP
                     TKYYSTPTDVFRQHGFSMVIWANHMLRAAVSVMQKTARALKQSENLLSIEDKVAPVSE
                     IFRLQNAAELLEAEERYLPRGAEGTSAVVLAASRGEELGELTVEQPKTMVKIQGTPIL
                     SHIVDAYNAVGMKDILVVRGYKKEAVNLPNLTYIDNADYSQTGELASLSLALQSRKGV
                     FQPTIVSYGDVLFNKYIPQALCQEPDDCVIFVDSNWRDQTTYARLGGFVECTIPNSRK
                     AFNAKVYLKQLGNRIPTDATHGVWMGFLKLSSSAACDINNLLVEMLREPENRKAGIPH
                     LLQELLRREYPIRVLYTVGHWLDINSLDDVVQAGNF"
     gene            7570..8058
                     /locus_tag="PK063_12315"
     CDS             7570..8058
                     /locus_tag="PK063_12315"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97882.1"
                     /translation="MRYHTLRQIILLLAGLTAVGCQSNPAVTSVRYDNVRFMDVWSTY
                     THCLSAEDSQVALQDSTKLRVVSRAQTTRSTLDTILPTSLKNMVSQPSSRLAVDVHAM
                     AASCSLHAGNLAMSAGELDVARSQFREVLQGHAESDYAYYTAQARERLTQLELTLQAA
                     LR"
     gene            complement(8096..9580)
                     /gene="glgA"
                     /locus_tag="PK063_12320"
     CDS             complement(8096..9580)
                     /gene="glgA"
                     /locus_tag="PK063_12320"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: protein motif:HMM:NF001899.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HMZ97883.1"
                     /translation="MVASEVVPLAKTGGLADVVGALAVEFAKLGHDVCVMLPAYRQVD
                     ELGYEMTEGVRLSVPAGPSVMDVRVQEVFAPPLHVQGPGRLRVFVVRHDPYFSRSGLY
                     QEAGRDYLDNLDRFVCFCRTVMEMCIHLSEHEGWQTDLLHLHDWQAALCAVYLRTLYQ
                     GRPSLRRIRSVLTIHNLGYQGVFPAAQFSSTGLPLHLFTPAALEFYGQINVLKGGLVS
                     ADLLTTVSPTYSLEIQSSEYGCGLEGVITERKSVLSGIVNGIDTESWNPATDQYLVAP
                     YHASDLAGKARCKKALQRELGLRPLKCPLLGVIARLTSQKGIDLVIDVLPELMELDVQ
                     VVILGTGEPHYEQQVGELAQRYPGKIAVRNVFDEGLAHRIEAGADMFVMPSRYEPCGL
                     SQLYSLRYGTVPIVRKTGGLADTVVAYTPRAFKESRATGFSFTDTSSASLLTCLLLAL
                     SVYRKKAEWQRLVKTGMAQDLSWSRSAAIYLQLFRDVISRAGDR"
     gene            complement(9637..10098)
                     /locus_tag="PK063_12325"
     CDS             complement(9637..10098)
                     /locus_tag="PK063_12325"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97884.1"
                     /translation="MNVSKLASVGLWLLIGLISVACSGLPPIDQQKRLVQAGELKIQQ
                     LTPRAFAETWGDPTYTHQQFTHFFGMPDGQLIPQARMALGESPQGWETGLAAGDAFFM
                     AYADRGYYLVFLEGVLVYHEAMSAEKVHAVGKTWKFESQFKTRLESSPGLK"
     gene            complement(10146..10502)
                     /locus_tag="PK063_12330"
     CDS             complement(10146..10502)
                     /locus_tag="PK063_12330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF971 domain-containing protein"
                     /protein_id="HMZ97885.1"
                     /translation="MGETVLEPVDMEWVEKGVLSITWSDGHKARYPVRYLRQHCPCAA
                     CTDEWTGELRLKPDDVPMVIMLQDIQPVGRYAFQFTWSDGHDTGIYSYSFLRRLCQCD
                     VCQPVKPVEPRSRRLL"
     gene            complement(10561..11319)
                     /gene="recO"
                     /locus_tag="PK063_12335"
     CDS             complement(10561..11319)
                     /gene="recO"
                     /locus_tag="PK063_12335"
                     /inference="COORDINATES: protein motif:HMM:TIGR00613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HMZ97886.1"
                     /translation="MPLVKTAAIVLHSRKWGDADRIVTCYTLRLGKLRGVARGARRLK
                     SRLGGMIEPFTLCQLDLFEKPGDSLYRISQVALDEPFAKLRSDLGLMTAAGRMVNLVN
                     AVMAEGDAEPRIFEMLESGLRTLLESRDAAWTTVLFQIRLLGITGFRPQTEQCATCGQ
                     VHRTPLPQFSPLAGGMVCERCASRQPFRCTALSRGSVAFLQQALHMQPALLNRLQAAG
                     QVRAEVESVIESYVTVVAGRRLPAVDFLTSGGPA"
     gene            complement(11374..12711)
                     /gene="mgtE"
                     /locus_tag="PK063_12340"
     CDS             complement(11374..12711)
                     /gene="mgtE"
                     /locus_tag="PK063_12340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HMZ97887.1"
                     /translation="MRLVSIQRLLRRGAITNLAKMLARMHPADIANVIDHLSSQKEKR
                     EIFELVRGDVKRGQVLSELDGESITLVLSDLLPSDSAWLLKDLGSDDIAHILSVIPND
                     RAKEILALMRTEDSTEIADLLKYPKGTAGGIMTTEFFALFEDATAQEAIRRLQQATDA
                     EMVFYIYVTDKEDRLVGVLSLRQLLTVPPATPLKNIMTRDLISVAVDMDQEEVSRQVA
                     SYNLLAIPVVEKDGKLVGIITVDDVVDVIREEATEDMLKMAGAVEEDAMFKSSSMAAA
                     RVRLPWLFTNLVGSLLSGMLLWMFRYTIQEVVAIVSFIPVIAAMGGNVGLQSSTLIIR
                     GLATGLVELTDVWKIFFREAKIAFLMGIACSLMLTVVGWLWHQVFLGMVVGVSLITAF
                     LVSTSMATVMPIVLKRMGVDPAVAAGPFVTTANDITGIAIYLTLATIFLEQIR"
     gene            complement(12818..13702)
                     /gene="era"
                     /locus_tag="PK063_12345"
     CDS             complement(12818..13702)
                     /gene="era"
                     /locus_tag="PK063_12345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HMZ97888.1"
                     /translation="MKFGSVAIIGRSNVGKSTLLNRLLKEKIAIVSDKPQTTRTRILG
                     VAHVEGAQIVFLDTPGFHEPHHLLNRRMVRTTLETFDDADVLYVVVEATSQPGPGDLA
                     VIEHVKQAVAKQARPVVLVINKVDLVNKSRLLPLMEQYLRIFPWTEMVPVSAQTADNT
                     DRLLSVTVSLLDEGEATYNEDMITDQSMRTLAAELIREKILQQTYEEIPHSVAVEIEE
                     FVETKKLIKIGAVVIVEKESQKGILIGKHGERLKSVGTAAREDMERLFGTKVFVKLWV
                     KVRESWREDEQTLAELGY"
     gene            complement(13699..14061)
                     /locus_tag="PK063_12350"
     CDS             complement(13699..14061)
                     /locus_tag="PK063_12350"
                     /inference="COORDINATES: protein motif:HMM:NF016839.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HMZ97889.1"
                     /translation="MIIKPNRGRDWLDWQRKLFSAGKWVGLGALFLMMGALLFGEMGI
                     SRYLHLREHAEQLDHELADLQRLNGELRADLDRVQYDSTRIEELARERLGYVRKGETV
                     YQLAPLGEKERLPTVKTP"
     gene            complement(14067..15353)
                     /gene="eno"
                     /locus_tag="PK063_12355"
     CDS             complement(14067..15353)
                     /gene="eno"
                     /locus_tag="PK063_12355"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014961761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HMZ97890.1"
                     /translation="MSGIRNVKARQIIDSRGNPTVEVEVLLESGAHGRAAVPSGASTG
                     EKEAIELRDGDKKRWMGKGVSKAVANVSKAIAPRLLGMEALDQAAVDHEMIALDGTKT
                     KGKLGANAILGVSLAVAKAAANETGQPLYRYLGGTNARVLPVPLMNIINGGAHADNRL
                     DLQEFMIMPVGAPRFSDALRMATEVFHTLKSLLKKKGLNTAVGDEGGFAPDLQSNEEA
                     LALIMEAIEAAGYRPGQDIALALDCAASELYEKGRYRLEAEKNPERSSEEMVSYYGKL
                     LDRYPILSIEDGLSELDWKGWKILTEKLGKRVQLVGDDIFVTNVEIFAKGIAEGIGNS
                     ILIKLNQIGTLTETLDAIELAKRSGYTAIISHRSGETEDTTIADVAVATNSGLIKTGS
                     LSRTDRVAKYNQLLRIEDELGAAAVYRGRTAVPSRT"
     gene            complement(15429..16862)
                     /gene="gatB"
                     /locus_tag="PK063_12360"
     CDS             complement(15429..16862)
                     /gene="gatB"
                     /locus_tag="PK063_12360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HMZ97891.1"
                     /translation="MSAAYEVVIGVEVHAQLRTQSKLFCPCGTTFGRTANSQTCPVCL
                     GLPGSLPVINEAAVEMAVRAGLAMNGTIGVHNRFARKNYFYPDLPKGYQISQYEAPIC
                     EHGWIEIAAGGTRKRVRIRRAHLEEDAGKNLHEAGSGMSLVDLNRAGTPLLEIVTEPD
                     LSSSEEVVAYLKALRELLMYLDVCDGNMEEGSFRCEPNLSLRPVGQKAFGTKVELKNI
                     NSFKFVKDAVDYEIKRQTKVLNEGGRIYQETRLWNHERGETAVMRSKEEAHDYRYFPD
                     PDLVPLEIAADWIEQLREGLPELASTKQQRFVAEYGIPEYDAGILTSSKALSVYFDAC
                     VKLYPHPKTVSNWVMGELLRELNHAGIQADASPVTPERLVELLTMVDQGAVSLKVARD
                     IFPEMYASGKPPAQIVQDKGLTQVSDEGALVSIIDEVLKKNPAQVAQFKEGKQQVLGF
                     LVGQVMKASGGKANPGKVNELLKKTLG"
     gene            complement(16859..17179)
                     /locus_tag="PK063_12365"
     CDS             complement(16859..17179)
                     /locus_tag="PK063_12365"
                     /inference="COORDINATES: protein motif:HMM:NF024143.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HMZ97892.1"
                     /translation="MADNHGPSSAAVLLGFLSGAALGAVAAILLTPRTGPESREMLRG
                     YARRAEDGLRDLVGEAGERFEGAVEEGRDFIESKKSVLREAFDAGREAMRREREQFSK
                     GEQG"
     gene            complement(17169..17570)
                     /locus_tag="PK063_12370"
     CDS             complement(17169..17570)
                     /locus_tag="PK063_12370"
                     /inference="COORDINATES: protein motif:HMM:NF017876.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HMZ97893.1"
                     /translation="MIVEVAAILVAIAFAVLVGYLVPLLIQVRKTAAEAEQLVTKMNT
                     DLPVLVTELRAMSQNLNDLTEQARGGVEHAAVLLHAVGEVGESVNQVHSLVRGSGGNL
                     LANVASVVAGLRAAKQVVTERLKEGGHHNGG"
     gene            complement(17589..19064)
                     /gene="gatA"
                     /locus_tag="PK063_12375"
     CDS             complement(17589..19064)
                     /gene="gatA"
                     /locus_tag="PK063_12375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HMZ97894.1"
                     /translation="MALTVLHKMTLAELQRKFTAGDVSATEIVRAYFLRVAHVEPKVN
                     AYLTQCKEAAVAQAERLDQSLKGWRKTTPLMAMPLAVKDNICTEGVRTTCASRMLESF
                     VPPYDATVVAKLRAQNYLLVGKTNLDEFAMGSSTENSAFGASRNPWNIQTVPGGSSGG
                     SAAAVAADECVASLGSDTGGSIRQPAAFCGVVGLKPTYGRVSRYGLVAFASSLDQIGP
                     ITKDVTDAAILLGAIAGHDPRDSTSANVPVPDYLKALKRKDLKRLKVGVPAEYFADGL
                     DPEVEQAVRTAIEGLRELGADIREIKLPTTDAAVATYYVIATAEASSNLARYDGVKFG
                     LRAGDSKDLLDMYLRTRAEGFGPEVKRRIMLGTYVLSAGYYDAYYGKAQAVRTLIRRE
                     FDAAFETVDLIVTPVTPTTAFKFGEKSQDPLQMYLSDIYTISANLAGLPAISLPCGFS
                     KAGMPIGLQLIGRPFEEDTLLRGAHAYEQATNWRSKKPLVR"
     gene            complement(19064..19429)
                     /locus_tag="PK063_12380"
     CDS             complement(19064..19429)
                     /locus_tag="PK063_12380"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004068 - aspartate 1-decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006523 - alanine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HMZ97895.1"
                     /translation="MFRQMLRAKIHRATVTEACLEYEGSLTVDEDLLDAAGILPYEAI
                     VCSNLNNGERFMTYAMKGKRGGGEIVLNGPTARKAAVGDQIIIFCYEYYSDEEIKRHK
                     PKIILVDGKNRIARKVAKR"
     gene            complement(19455..19748)
                     /gene="gatC"
                     /locus_tag="PK063_12385"
     CDS             complement(19455..19748)
                     /gene="gatC"
                     /locus_tag="PK063_12385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HMZ97896.1"
                     /translation="MEITKQEVEKVAKLARLALSEAETTAFSQQLNQIVGYVQKLKSF
                     STEDVEPTSTVLGQTNVFRPDQVQASLSPEQALGNAPDAEAQCFRVPKIIQES"
     gene            complement(19866..21698)
                     /gene="glmS"
                     /locus_tag="PK063_12390"
     CDS             complement(19866..21698)
                     /gene="glmS"
                     /locus_tag="PK063_12390"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:0006040 - amino sugar metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HMZ97897.1"
                     /translation="MCGIVGYVGNQDAVPILLNGLSKLEYRGYDSAGVAIQRGEKIDI
                     RRSVGKLINLQNSLAQKAIAGMCGIGHTRWATHGKPSEQNAHPHRSENCVLVHNGIIE
                     NYVELKQRLIKDGYKFQSETDTEVVAHLIDTHIKKDKLHLADAVRATAREIRGSYAIA
                     VISEHEPGLLVAARSGCPLVIGRTAEASFVGSDVMAMLSHTRDVTFLEEGDVAEVTAG
                     GVTFTDLDGRAVTRKKTKVTWDASAAEKSGYPHFMLKEIHEQPQTILDTIRGRYSYES
                     GEADLPDIGLTPKQFADVGRIWIVACGTSWHAGLVGKYLLEEMVRTPVQVDIGSEFRY
                     RDPLIEKNDLFITISQSGETADTLAAAREAKQKGARVVSIVNVVGSTLARESDGVLYT
                     HCGPEIGVASTKAFTSQLAALYMLALHLGRVRGVLTAADGKAWLDRLVTVPALVKHVL
                     GREAEILAIAKRYYKKPDFLYLARGINFPIALEGALKLKEISYIHAEGYAAGEMKHGP
                     IALIDKDMPVVVLAPRDRLYEKTVSNLMEVKARRAPVIAFVAEGERELGKIADAVFTI
                     PDVHPLLSPILFTIPLQLLAYHIAVLRGEDVDQPRNLAKSVTVE"
     gene            complement(21708..23321)
                     /gene="glmU"
                     /locus_tag="PK063_12395"
     CDS             complement(21708..23321)
                     /gene="glmU"
                     /locus_tag="PK063_12395"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: protein motif:HMM:TIGR01173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HMZ97898.1"
                     /translation="MTHASHDNASSSSIPGLGVIIMAAGLGKRMKSALAKVLHPVAGR
                     PMVLYVLDIACGLAEQGVAVVVGHQGADVRKVVEAVGGQVAVAEQTKQLGTGHAVLQA
                     RPVFGDAAHRKPTRYLILNGDTPLLTEATVRELLAMHDAQGAAVTLLTAVLDDASGYG
                     RVIRHRREEWLQGAADNRVQSIVEDKDASHAERSVREINVGTYVVDGEFLFPALDKLD
                     PRNAQGEYYLTDIVQMAVQQGRTVSALRLRDIDEGLGINSRVQLAEAEGVIRRRIRER
                     WLEAGVTMLDPASAWIDADVTIGRDTLLYPNVTLEGRTVIGENTVVHSGTRITDCTIG
                     QRVEILDHCIFRESQVEDDSHLGPFVHLRPGVVVRRKGKVGNFVEMKKTELGEGSKAN
                     HLSYLGDAMIGQGVNIGAGTITCNYDGYKKFHTVVGDGVFIGSDVQLVAPVTVGQGSV
                     IAAGATVTQDVPADALVIARVPQVTREGWAARRRALQSGQVPPPAPKPVPPVKARASA
                     TPAKAASKPKPRTRAAKKKQPAVQRSKRR"
     gene            complement(23373..24047)
                     /locus_tag="PK063_12400"
     CDS             complement(23373..24047)
                     /locus_tag="PK063_12400"
                     /inference="COORDINATES: protein motif:HMM:NF016270.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF502 domain-containing protein"
                     /protein_id="HMZ97899.1"
                     /translation="MVQASLKRYFLTGLLVMIPIWGTILILKTLFVSLDGILGDAAAR
                     LVTPGYYVPGLGIIALILLIFMTGLFAANFIGRQVVRQWESLLNRVPVVRGIYSTIKS
                     MMDILSFAERESYRRVVLIQFPKNGHYCFAFVTGVTKGEMQQLSPDPLVHVYVPTSPN
                     PTSGYFLLVPEREVIAVDITVEEAMKLIVSGGLYTPTQPSGAGSQAGGKTWTPIKQPD
                     AGVQVG"
     gene            24182..24904
                     /gene="tmk"
                     /locus_tag="PK063_12405"
     CDS             24182..24904
                     /gene="tmk"
                     /locus_tag="PK063_12405"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HMZ97900.1"
                     /translation="MMKHYRPPRGLFITLEGIEGCGKSTQARLLGEYLRSQGHVTVET
                     REPGGTPLAEKVRSVLLDRADEPVAPETEAFLVLAARRQHVAQVIEPALEQGAIVLCD
                     RFSDSTLAYQGYARGLNVPLLERLNRLATHAVMPHLTLLFDLPVATGLARRRSASETN
                     RLDRESLRFHQKVRAGFLDLAKRHPARIKVIPSRGSKETVARAVARIVAPALNRIHRA
                     DHQTAKPRATSSHTTQVRHALR"
     gene            24891..25922
                     /gene="holB"
                     /locus_tag="PK063_12410"
     CDS             24891..25922
                     /gene="holB"
                     /locus_tag="PK063_12410"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: protein motif:HMM:TIGR00678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HMZ97901.1"
                     /translation="MPFADIIGHEHAKTLLRSAILQNRLAHAYLFHGDDRIGKRLLAW
                     RLAQTLLCETVSDGRQPDACGTCRACQQVDARTHPDFLVIEPDQEMANPQIKIESIRD
                     IEHQMIYRPLIGNRKICLIDEADRMTIGAANALLKTLEEPPDHSLFILVSSRPYALPA
                     TIRSRCQALRLTAPAQTQVEAAVILKRELPPADAHFLALLSDGQLGRALECDLEQART
                     TQKEFAAIFSAKGLQSFSTVLAAAEALAKGDRGPEAFDWLLRWLRDILLIAVGAGSDH
                     ILNLDQRAGMQALAAHINIDDLLDLIGDLEKMERQAHRNLNVQIALETILLRVRQLLT
                     PSGTAERSR"
     gene            26028..>27903
                     /gene="metG"
                     /locus_tag="PK063_12415"
     CDS             26028..>27903
                     /gene="metG"
                     /locus_tag="PK063_12415"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HMZ97902.1"
                     /translation="MSTRDTFYITTPIYYVNDVPHIGHAYTTVAADVLARYWRLRGRD
                     VFFLTGLDEHGQKVQQAAAKAGIDPQAHCDRLAPQFTNLWDRLNISHNAFIRTTDKPH
                     QSVVQRYLQQLFDKQLIYKADYTGWYCTFDERFWTEKDVVGGLCPDCKRPIEQLSEHN
                     YFFKMGQYQEQLQRHILEHPDFIRPESRRNEVLGFLQTQKLGDLSISRPKSRLSWGIE
                     LPFDKDYVTYVWFDALVNYISALEYLPQGQPAGLRYWPADVHLVGKDILTTHAVYWST
                     MLIALEQPLPKTIFAHGWWTVDGEKMSKSRGNVVDPNKMVDQFGTDAFRYFLLREVPF
                     GQDGDFSHSALVTTVNAKLANGIGNLLSRTLTMIERSCAGVIPERGPAVLPELEQRIE
                     ELATQLPGKTETGFNALQFRDVLLMIEELNGCCDEYIDKSAPWKLAKQPETQPQLHTV
                     LNTSARALRLLALLLYPFMPKAAAQMIEQLGLSLDLSRPLAAEAGRWDAPLAGSKIQK
                     GASLFPRIESKPQGAKPVSDTPASPQPTAAAPSAAPAAPQSPAPAATPAAAPAPAQPA
                     QISIDDFMKIQLKAAKVLAAERVPKSEKLLKLQVSLGTEQRQIVAGIGKKYEPEALVG
                     K"
BASE COUNT         6252 a         8715 c         7020 g         5816 t
ORIGIN      
        1 ctgaaatcac cagccacttt cggctgacaa ctgctcgcca ataatcctcc ggagacaagg
       61 tgcgcgtgtt catttctttg tatccactcc tcctgatcca gacttgctag ctcctccatc
      121 gacagacgaa gaaaccccag aagcaccttc ccataaggca ccggaacgga agaaatcacc
      181 gcgtggggcg taggcgtagg tgaatcctaa cagaatgaca tgcttggaga atcccaaatc
      241 ccccgcactc aagccactcg tttgattgtc aaacattaac cattgatggc taagcctcgc
      301 ggtaaatgtg ggagtaatga gatagtttaa agatactgtc gtaccgtaag ttgtaaaagt
      361 agtgccaatg gcatcggagg taaaactgct tcgtgcagca ttgaaaaggg cttgagccgt
      421 cagcttgtcg gtgattccag ctgaacttgc caacgagaca gtgtgcgtgt agatcgggcc
      481 tgcagactca acaaagctag gaaatacgcc caaattataa aggagagtta ttcgatagga
      541 tccgggtgat gcaatacctc ccggcatatt catccccgaa agcaggggaa gaaagtttcc
      601 acccattgaa gaggcgcccc cagtccccgt cgcctcttgg aaatcgctgc ccaactttcg
      661 gaggaacgaa gaacctgaag catacgtcag actcacgcct ccagttggaa acattgtggc
      721 cggaatccgt cgttgcccac caaaagcaga cgagtctgga atcggctcaa taagcgttag
      781 acctccattg agggaagaac tcagttcttt ggtccacgct cgtccccatc caacgttgcc
      841 tccatgcgtt gtatattccc caaattgcgg ctgggaagtc tgtgtaaaca catacttcac
      901 agtcaacgtg tcgatggcgg tgattctcga tgagggaccc gcggtaatgg aatgtgtgct
      961 cgtatcaaac actgtttgcg acgcttgacc taccgtccca gaagtcggcg taaatgaacc
     1021 accaaaactt agctgggagt acgtgtaagt ggtttggaag tccgtggttg gggaaagcga
     1081 atacgaatcc gcaagaccag cactatacat agtggtccta atgcgttggg taagaagacc
     1141 tgagtctacc ggaccggaga ttccaactcc ccctgtcccg aaccctcccc cccccccaaa
     1201 tcctccaccg agaccgccaa ctccaaaggc aggagtcgag ggactgtaac gataggttcc
     1261 aaatatgcga aatgctttca ttctcggcaa aactcggttt acagcctgag ataaatcgac
     1321 gcctccagac gcattaaatc ccacgttatc aaggtcggag ttatgtgcaa atttctgaac
     1381 aactgccccg agggaaagat ttgttttcac aaggttagtg ttgtgcataa aattcagctg
     1441 aggcgtaatc gtcgtaatga gatcatcggc ctttgttcct ggggccaatt gagattttgg
     1501 agtgaagaac acgttgctgt cgtattgctc aagaaccgaa attgatggca caacacgtat
     1561 ttgctgagcc gaagatggtg acgcgaacca gcatgacacg aacgcgagtg tcaaacatat
     1621 taaagcgaat ttacccatcc tcaaaaactg gtcacggcac aacaatgaca tcaccagcct
     1681 tgaggaaaaa atttccctcc gaatttttac cttgcagaat gtcttcatag ggaaccggga
     1741 tctggacctg ctttggttga ccttggccat ttggaacgac tcgcagtaca tggatcttat
     1801 ttctcgaggc aaacgtcgta aatccgccag ccaatgatat gccttgcaaa actgtagcat
     1861 acgactttaa cggaacctta cctggcttcg agacctctcc taatacatat acgtaatagc
     1921 tattaacctc tttgacctgg actgaaactg tgggattgga catgaactca gccaatccat
     1981 cagcaatacg cttcgccaac acatttgagg tcatgcctgc cgcttgaacg tcaccgacca
     2041 acggcatgga gattttccca tcaggtcgaa taataacttc ccgggaaagc tcctgatttc
     2101 tccacacatt tacaacaaga acgtcttcag ggcctaacaa aaactcattt gggggaatat
     2161 aggtgacgtt aaagtctatt tgctcgttgc ctatccaaca tcctgggaga gtcagaagca
     2221 cactaaaaac aatacatacc ccccctcgta accatctgca accgaaagtt ttcactttcc
     2281 taactccttt ggctcgtcga cacgaaatat cgtctgagca ccttgactaa cgacaattat
     2341 ctggacggca atacaaccat agtttcagac ggtacaacga tctgatctcc cggcttgagt
     2401 tcgatgtttt gatctgagcc atctcttaag acgatatcgt cataactggc cttaattttg
     2461 ttaagcccct cgccgtcttt tccgaatcta aagaccacaa tcttgttacg ggcggccact
     2521 tgggtaaatc catgagctat ggttatcgct tgcaacaggg tggtcttact tttcagtggg
     2581 tacttcccgg gcgcattcac ttcccccagg acatagattt ggtagctgtt cacttcccga
     2641 accaggatgg aaacggtggg attctccata taagacttta agcgtgcaga aatttcttcc
     2701 gttagttgtg cagcggtgcg gccaacggct gaaacgtcac cgatcaatgg aagagaaatt
     2761 cttccgtcag gtctgacctg gacttgcttc gaaaggtccg catttttcca cacggtaatt
     2821 tccagaacat cctcaggacc cataatgtaa tccggcgtca cggtcaagga agacttttct
     2881 gctccatccc ccccatgacg catccctgaa ggaggtgccg ctgcaggagc tccggctacc
     2941 agagtagcct tgggggcctg atcaaacggg ccggcaaatg caacgttgag gcaatttcca
     3001 gccaggacca ttaggctcaa tacgacctta gctttcatga cttattctcc tgaaagaatt
     3061 ccggttgccc attacagcac agcgctctga gaccgttctc aagttcagcc gattgcgatc
     3121 aaatccctga atgttcccaa tcgtctcggt cacacacatc cctcaatccg acaccccaat
     3181 tcatcccata acacattgtt taaattgcac aaaccttgga agctatcgat tttttaggat
     3241 aatgggtgcc ttatgctaaa gaatcaaccg agaggaatgg gcaaatacgg acaaatcaat
     3301 gctggctctc atactaaaga agtccgccac cgttttgaag tatagaatca atggtctcac
     3361 tggacaatac caatgatgta cggaccgccc ccccgaaggt atcatttgac tacctcgaaa
     3421 gtattatgta gcattactag taacgctgac acactgtagg ttatcagaaa tcgaccagtt
     3481 gtcgaggaac attcagcatc atacggagta ttgccgtggc tcaaatcgct ataacctcgc
     3541 aagaaaccgc ggacaacttg gcagatcaac gcacgggggc gggaattgtc gttctgtcgt
     3601 cctccatgca actcctacat atgaaccggc aagccgctga attatcgaag ctcattaata
     3661 tggcagaaaa aggtggtacc ccagctaaag cggctcaagg agtgcttcca tccgctctta
     3721 ctgagctctg caccgaaatc ctgaaagcgc tccaagttcg cacagaggca aaggattggg
     3781 agcaattcga ggtcaaaaaa attgcgggca acccgaatca acccgtgctc ttgcgaggat
     3841 ttggtctccc ggatagaggt ggtgttcaat atgcgcgcct agtggtcaca ttggaagagt
     3901 tgggtcgtcg gcaacaactc aatactgacc aagctaagga acgcttccag ctgacaaatc
     3961 gggagcaatc ggtggtcgaa aacctagcga aaggatggac gaataaagaa atagcaaacg
     4021 cactgaaaat caccgaacag acggtcaaag aacacatcaa gcacattatg cgaaaaacga
     4081 actccacgac gcgtacagga gttctcgttc agatctttaa atcgtaagcc caatgcgtca
     4141 atcatttccc taatnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnngcgatc
     4261 tcaagaattt cgatctcgag ccccaccgtt ggttgtccac ccactgaatc atgcgcacca
     4321 ttgttgaaaa caatatgctt aaagttttcc ggcttcaacg ttccagtaat gggaagcgct
     4381 cccatgtgca tgagaacagc accatcccca tccagacaat agacggaacg gctgggccgt
     4441 tgaagggcaa cacctaacgc gatctgagaa gcatgcccca ttccgccgac ggtgagaaaa
     4501 tcccgctcgt gcccctgccc tttattcatt ctatattcat agacttcacg ggaggccatg
     4561 ccggtggtcg acacgacaac atcacgttcg tccaagtgtt ccagcacctg ctgaatcgca
     4621 gcttctcgcg tcaattcgaa aatctccgtt ttcctcttat cgccggtgaa ggcgccgaag
     4681 gtacccttct tgatgacaag tgcgaacggg gcattatgct tctggacata ggccagggcg
     4741 tcactcaacg ctccttcagc ctcattcact tcagggccta aaatggagta cggaatctcc
     4801 atagcgtcca gcatagcaag catgacacgc ccctgcttct tgtgttgagg ctcgtcatgc
     4861 acacccgtct cgccccgcca gccaatcacc agcagcaggg gtatcgaata cacttccgca
     4921 tcagccaggg acaacaacgg attgatgatg ttccccagcc ccgaattttg cagatacact
     4981 aatggaactt ttccggtcgc gaggtggtag cccagcgcca gcgccacagc gccgccctca
     5041 ttggcactga tgatgtgccg accggcttga ggcacctgct ctaggcaagc acagaattcc
     5101 ttgagcagcg aatcgggcac accagtgaaa aactccacac tgtttgactg taaacattcg
     5161 acaaatttcc gaggatcaat catgcacaag ttctccaacc taagacgtcc cgatgagacg
     5221 atacagcgat gaacttcaca gactggctgc cacccgtttc aaaacatcac cagcggacag
     5281 aatgcgagcc atcaaaaatt tccggcctgc accacatcat cgaggctatt gatatcgagc
     5341 caatggccaa cggtatacag cacccggata ggatattcgc gccgcaacaa ttcctggagc
     5401 aagtgaggaa taccggcctt gcgattctcc ggctccctca gcatctctac gagaagattg
     5461 ttgatatcac aggctgcgga cgaagagagt ttaagaaatc ccatccacac tccgtgggtg
     5521 gcatcagtcg ggatccgatt tcctaactgc ttcagataga ctttcgcatt gaaggccttc
     5581 cgtgaattgg gaatggtgca ttcgacaaag cctcccaaac gcgcatacgt cgtttggtcg
     5641 cgccagttgc tatcgacgaa tatcacacag tcatccggct cttggcacag cgcctgcggg
     5701 atatacttgt tgaacaacac atcgccatac gaaacgatag tcggctgaaa aactcccttc
     5761 ctggattgca acgccagcga taatgaggct aactcgccag tttgcgaata gtccgcattg
     5821 tcgatatagg tcaggttggg aaggttgacc gcttcttttt tgtacccccg gaccaccaaa
     5881 atatccttca tgcccacggc attgtacgca tccacgatat gagacaagat cggtgtgccc
     5941 tgaattttga ccatggtttt cggctgctca accgtcagct cacccagttc ttcacctcgg
     6001 gatgcagcca acaccaccgc tgacgtgccc tcggcgccac gagggagata ccgctcctca
     6061 gcctccagca gttcggcggc attctgcaaa cggaagattt ctgaaacagg ggccaccttg
     6121 tcttcgatgg acaggagatt ttcactctgc ttcaaggccc gtgcagtttt ctgcatgacc
     6181 gacaccgctg cacgaagcat gtggttggcc cagatcacca tcgagaagcc gtgctggcga
     6241 aagacatccg ttggcgtgga ataatacttg gtaggaacga tgacaacggg acaccgattt
     6301 ccccattctc gcttaaaggc caggatctca tcaggaacag acagggcact atggatgaga
     6361 ataccgtcag ccccggcctg gtgatacgct tcagcgcggc gcaatgcctc cgtcaaaccc
     6421 cagccacaga taaaggcttc cactcgtgcg atgacgcaga aatcgggatc ggtttgggca
     6481 tctttcccgg ctttgatttt gccgcagaat tcatgcatat cggccatcgg ctgcgcatcg
     6541 ccctttaaaa agctgttggt cttgggaaag agcttgtctt cgatgcacac ggccgcaatg
     6601 ttgcgctgtt ccagcttacg gatgaggcgc tgcatgttgt tgaaattgcc gtaccccgta
     6661 tccccgtcga gaagaatcgg aatgttagtg gcatcggaca tgaattccag atcctcgagc
     6721 acctgagtcc agctcgcttc gttgttgtca cgcacgccaa actgagccga gattgaaaga
     6781 ccgctggccc agatacccgg gaaccccgcc tcctctacaa ttttggcact gagtccgttg
     6841 tgcgcttcac aaataaactc cagttgctcg gagaggagca aatttcgaaa ctggcgggtc
     6901 ttggttaacg gttgtctcga attcattggc gaaggaacct ttcctgagga agttctgtct
     6961 cgttcgtcga cgaagatatt cttcgtacca tatgaaagac catcaagtcg caagaatatt
     7021 cgtcgtcaat gattcgcgaa tcgcacccat tctttctgag agatgaatga gtcgagaacg
     7081 catatgtcgg cccagagtaa ggtcggcaca tttccgtcgc gatggccaga tagtagccga
     7141 gcctgcagcc ctggcgctac cgattcttga cagacaagca acgatacccc ataggcctgc
     7201 cttgacgcct ctgtgcatct tcactgacga attgggatac attcggttag ttcaaaccgt
     7261 ccgcagtgtc caggacgcga tcgacagcac cagccatcgg ccggaaagcg acacttcccg
     7321 caccctccag gatcttcctc acttcgtgag cctcggcctg ctcaacagcc cttcatctgg
     7381 cctgtgccgc gtggcctcat catccgtgtc gtattcccca cagtgaactt aaattgagac
     7441 agcaccgctt cagaggatga caaatggcca caattaattc aatgacttac atgtgccaca
     7501 cgtggcgcaa gacttgctca ttccgaggac aagacaagag tcgagggcag atcgacaaag
     7561 actggcacca tgcgatatca caccttacgc caaatcatcc tcttactcgc gggcctcaca
     7621 gccgtaggct gccaatccaa tcctgccgtc acctcagtgc ggtacgacaa tgtccgtttc
     7681 atggatgtat ggagcaccta cactcattgc ctctcagcgg aggacagcca agtagccttg
     7741 caggactcca ccaagttacg agtcgtcagc cgagctcaaa ccacgcggtc gacgctcgat
     7801 accatcctgc ctaccagcct gaaaaatatg gtcagtcagc cgtcctcgcg cttggcggtg
     7861 gatgttcacg ccatggccgc atcctgcagt ttacatgcgg ggaacctggc catgtcggcc
     7921 ggtgagttag acgtggcgag gagtcagttt cgagaggtat tacaggggca cgcggaatcg
     7981 gattatgcct actacactgc acaggcacgg gagcggctca ctcagctgga actgacactc
     8041 caagctgcgc ttcgataacc ttcctcattt cttcctcgcc ccaacgcaac gagttttatc
     8101 gatcgcctgc tcgagatatc acatctctga ataattgtag atagatcgct gctgaccgac
     8161 tccatgagag atcctgtgcc attccagtct tcacgagacg ctgccactcg gctttctttc
     8221 gatacaccga caatgcgagt aacaggcagg taaggagcga cgcagaactg gtatccgtaa
     8281 aactgaaacc ggtcgcccgg gattccttaa aggctcgcgg ggtataagcc acgaccgtat
     8341 cggccaaccc gccggtcttt ctcacaatag gaaccgtccc ataacgtaaa ctatacagct
     8401 gactgagacc gcaaggctcg tagcgggatg gcatgacaaa catatccgcc ccggcttcaa
     8461 tccggtgagc caatccttca tcgaacacat tccgcaccgc aattttcccc ggataacgct
     8521 gggccagttc acccacctgt tgctcatagt gcggctcgcc agtgccgaga atcacaactt
     8581 gcacatcgag ctccatgagc tcgggcagca catcgatgac gagatcgatg cctttttggc
     8641 tggtcagcct ggcgatcact ccaagcagcg ggcacttcag cggacgcagt cccaattccc
     8701 gttgaagcgc cttcttgcag cgagccttcc ctgcgaggtc ggatgcatga tagggagcca
     8761 ccagatattg gtccgtggcc gggttccaac tctccgtatc gattccgttc acgatcccag
     8821 acagcacgct cttgcgctca gtgatcaccc cttccagacc acatccatat tccgagcttt
     8881 gaatttccag gctgtaggtg gggctgaccg tggtcaggag atccgcggag accagcccgc
     8941 ccttcaacac gttgatctgt ccatagaact cgagggctgc aggcgtgaac agatgcaacg
     9001 gcagtcccgt cgaagaaaac tgcgctgcgg gaaacacccc ctgatatcca agattgtgaa
     9061 tcgtcaagac gctacggata cggcgcaatg agggccgtcc ttgatacagc gtccgtagat
     9121 agaccgcaca gagggcagct tgccaatcat gaaggtgcag gagatccgtc tgccatcctt
     9181 cgtgctcgct gagatgaatg cacatctcca tgacggtccg gcagaagcag acaaaccgat
     9241 ccaggttgtc gagatagtcg cggccagcct cttgatacag accagaacga gaaaaatacg
     9301 gatcatgccg aacgacaaag acacgcagcc gcccaggtcc ctgtacgtgc agcggcggtg
     9361 caaacacttc ctgcacgcgc acatccatca cgctaggccc ggcgggaaca gacaaacgga
     9421 cgccctccgt catctcatac cccagctcgt cgacctgtcg atacgccggc aacatcacgc
     9481 agacatcgtg tcccagcttg gcaaattcga ctgccagcgc gccgacaaca tcagccaggc
     9541 cacccgtttt cgccaacggc acgacctctg atgccaccat gcaaatcttc aaggaagttt
     9601 gatccggagt cagattcatg gagaaaacac gaccgcctat ttcaaaccgg gggaggattc
     9661 aagccgcgtc ttgaactggg actcgaattt ccacgtcttg ccgaccgcat gcaccttctc
     9721 ggccgacatg gcctcatggt agacgagcac accttcaaga aacacgaggt agtatccgcg
     9781 atcagcatag gccatgaaga aggcatcccc agcagccaat cctgtttccc atccctgggg
     9841 tgattcgcca agcgccatgc gcgcctgagg aatcagttga ccatcgggca tgccgaaaaa
     9901 atgggtgaac tgctgatggg tgtatgtcgg atcgccccag gtttcggcaa aggcccgcgg
     9961 cgtcaattgc tgaattttaa gctctccggc ctgaaccaat cgtttctgct gatcaatcgg
    10021 agggagaccc gaacaagcca cagaaatcag tccgatcagc agccacaaac ccacggatgc
    10081 cagtttagag acgttcatcc gatcccgcct ttccctgttc atctgtaaac agcgaccgca
    10141 tctcatcaca gcaaccgtcg agaccgcggt tccaccggtt tcaccggctg gcacacatca
    10201 cactggcaga gccggcgaag aaacgagtac gagtagattc cggtatcgtg cccatcactc
    10261 caggtaaatt gaaaggcata ccgtcccacc ggctgaatgt cctgcagcat gataaccatc
    10321 ggcacatcgt cgggcttaag gcgaagttct cccgtccatt catccgtaca cgcggcgcac
    10381 ggacaatgct gccggaggta gcggacggga taccgggcct tgtggccatc actccacgta
    10441 atgctcagca cacccttctc gacccattcc atatcgacgg gctcgagcac cgtttcaccc
    10501 atagcgatca acgctccctc acgccttgaa taggaaacct tgcgaacacc accgtcgcac
    10561 ttaagcaggt ccgccgctgg tcagaaaatc cacagccggc aaacgccgac ctgccactac
    10621 cgtaacataa ctttcaatca ccgattcgac ttccgcccgc acctgccctg ccgcctgcaa
    10681 tcgattcagc agcgccggct gcatgtgcag ggcctgctgg agaaaggcca cgctgccacg
    10741 cgacaaggcc gtgcaccgaa acggctggcg actcgcacaa cgctcacaga ccattcctcc
    10801 ggccagcggc gaaaattgcg gaagcggcgt tcggtgtact tgtccgcagg tcgcgcactg
    10861 ttcagtttgc ggacgaaatc cagtgatgcc cagcaaacga atctgaaaca acacggtggt
    10921 ccaggccgcg tcccggctct ccagcaacgt acgcaggccc gattccaaca tctcaaagat
    10981 gcgcggttct gcatcgccct cggccatgac ggcgttcaca agattgacca ttcgcccggc
    11041 ggcagtcatc aatccgagat cgctgcgaag tttcgcaaac ggttcatcca acgcgacctg
    11101 cgaaatgcgg tacaaggaat ccccgggctt ttcaaacaaa tccagctgac aaagcgtaaa
    11161 cggctcgatc atgccaccca agcggctctt caaccgcctc gcccctcgcg ccacgccgcg
    11221 cagtttcccc aaccgcagcg tgtaacacgt gacaatccgg tcggcgtcgc cccatttccg
    11281 gctgtgcagc acaatcgcag ccgtctttac cagcggcatc tcttcaccct gccctgcgaa
    11341 tgacttggga acgaggaggt gcgcacggca tccttatcgg atctgctcga ggaagatcgt
    11401 tgccagggta aggtaaatcg caatcccggt gatatcattg gccgtcgtca caaagggccc
    11461 ggcggccacc gcaggatcga cacccattcg cttcaagacg atcggcatga ccgtagccat
    11521 gctggtggag acgagaaagg ccgtgatgag cgacacccct accaccatcc cgagaaacac
    11581 ctggtgccac aaccatccga ccaccgtcag catgaggcta caggcaatcc ccatcaggaa
    11641 ggcgatcttc gcttcacgaa agaaaatctt ccagacatcg gtgagctcga cgaggccggt
    11701 cgccagccct cgaatgatga gcgtagagga ctgcagcccg acgttgcctc ccatcgccgc
    11761 gatgaccggg atgaaactga caatggcgac gacctcctga atcgtgtacc ggaacatcca
    11821 gagcagcatc ccggacagca ggcttcccac cagattggta aacagccatg gcaagcggac
    11881 acgtgcggcg gccatgctgg aggacttaaa catcgcgtcc tcctcaacgg cgccggccat
    11941 cttcaacatg tcttccgtgg cttcctcgcg gatgacgtcc acgacgtcat ctacggtgat
    12001 gatgccaacc aatttcccat ccttctcgac gaccggaatc gcgagcaggt tataactcgc
    12061 cacctggcgc gagacttcct cctgatccat gtcgacggcg acactgatga ggtctcgcgt
    12121 catgatgttc ttgagcggcg tggcgggggg aacggtcagc aattggcgaa gtgacaagac
    12181 cccgacaagg cgatcctcct tatcggtcac ataaatgtag aacaccattt cggcgtcggt
    12241 cgcctgctgc aggcggcgga tcgcctcttg agccgtggca tcctcgaaga gggcgaaaaa
    12301 ctccgtggtc atgatgccgc cggccgtgcc cttggggtac ttcaacaggt cggcgatttc
    12361 agtggagtcc tccgtccgca tcaacgccag gatctccttg gcgcgatcgt tcggaataac
    12421 gctcagaata tgggcgatgt cgtctgaacc gaggtctttc aacaaccagg cggaatcgga
    12481 cggcagcaga tcggacagca ccaacgtgat gctctcgcca tccaattcgc tcagcacttg
    12541 cccgcgcttc acatctcccc gcaccaactc aaagatttcc cgtttttctt tctgcgagga
    12601 gaggtgatcg atcacattgg caatgtctgc cggatgcata cgcgcgagca ttttcgccag
    12661 gttggtaatg gccccgcgcc gcaggagtcg ttggatggag accaggcgca catcggactt
    12721 cgcttgcccg tgaccagcgg cctcgcgaga cagatctttc ccaagcggct ccttctccgg
    12781 gagtcgcgcc ggttccggcg gttgaatggt gaggtcgtta ataacctaac tccgcgaggg
    12841 tttgttcgtc ctctcgccac gattcgcgca ccttgaccca caattttaca aacactttcg
    12901 tcccgaacag ccgttccata tcttcccgcg ctgccgtccc cactgacttg aggcgctcgc
    12961 cgtgtttgcc gatcagaatc cctttctggg attccttttc gacaatcacc acggccccga
    13021 tcttgatcaa ttttttcgtt tccacaaact cttcgatctc gaccgccacg gagtgcggga
    13081 tctcttcgta agtctgttgc agaatctttt cgcggatgag ctccgccgcg agagtccgca
    13141 tggattgatc cgtgatcatg tcctcattgt aggtggcttc cccttcgtcc agcagcgaca
    13201 ccgtgaccga caagagccgg tcggtattgt cggccgtctg cgccgagacc ggcaccattt
    13261 ccgtccaggg gaaaatgcgc agatactgct ccatgagagg aagcagccgc gacttattca
    13321 ccagatcgac tttgttgatc acgagtacca cgggccgcgc ctgtttggcg accgcctgct
    13381 tcacatgttc aatcaccgcc agatcaccgg ggcccggctg ggacgtggct tcgacgacca
    13441 catacagcac atcggcatcg tcgaaggtct ccaacgtcgt ccgcaccata cgacggttca
    13501 atagatgatg cggctcatga aaccccggcg tgtcgagaaa aacaatctgg gcgccttcca
    13561 catgcgccac acccagaatc cgtgtcctgg tggtttgcgg cttgtcggag acgatggcga
    13621 ttttttcctt cagcagacga ttcaggaggg tagacttccc gacattcgaa cgcccgataa
    13681 tggccacact gccaaacttc atggtgtttt cacggtcggg agccgttcct tttctccaag
    13741 cggcgcaagt tgatacacag tttccccttt tcgcacatag cccaaccgct cgcgagccag
    13801 ctcctcgatg cgagtcgagt catactgcac gcggtccagg tccgcgcgca gttcgccatt
    13861 caaccgctgc aaatcagcca gctcgtgatc caactgttcc gcatgctcac gcaaatgcag
    13921 atatcgggaa atacccattt ccccgaacaa cagcgcgccc atcatcagga acagcgcacc
    13981 gagccctacc cacttcccgg cagaaaagag cttccgctgc caatccaacc agtcgcgacc
    14041 acggttcggc ttaatgatca cagtcgttag gtcctcgagg gaacagccgt gcggccccga
    14101 tagacagccg cagcacccag ctcatcctca atacgaagaa gttgattgta tttggcgacg
    14161 cgatccgttc tggatagcga gcccgtcttg atcaatccac tattggtcgc caccgccacg
    14221 tccgcgatcg tcgtgtcttc cgtttcgccc gagcgatgcg aaatgatggc cgtgtagcct
    14281 gaccgcttgg ccagttcgat ggcatccaac gtctccgtca aggtgccgat ctggttgagc
    14341 ttgatcagga tcgagttgcc gatcccctcg gcgatgcctt tggcaaagat ttcgacattg
    14401 gtcacaaaaa tatcgtcgcc gaccagctgc acgcgcttgc cgagtttttc cgtcagaatc
    14461 ttccacccct tccaatccaa ttcactcaaa ccgtcttcga tcgaaaggat ggggtagcgg
    14521 tccagcaact tgccgtaata ggagaccatt tcctcggaag accgctcggg attcttctcc
    14581 gcttccaacc gatagcgtcc cttttcatag agttcactcg cggcacaatc caaggccagc
    14641 gcaatgtcct ggcctggacg atacccggcc gcttcaatcg cttccatgat caaggccaat
    14701 gcctcttcgt tcgattgcag atccggcgcg aagcccccct catcccccac cgccgtgttc
    14761 aatccctttt tcttgagaag ggacttcagc gtgtggaaca cttccgttgc catgcgcaac
    14821 gcgtcgctga aacgaggcgc gcccaccggc atgatcatga attcctgcag gtccaaccgg
    14881 ttgtcggcat gcgcgccacc gttaatgatg ttcatgagcg gtaccggcaa cacccgcgcg
    14941 ttcgtcccgc cgagatagcg atacaagggt tgcccggttt cattcgcggc agccttggcc
    15001 acggccaggg acacgccaag aatggcattc gcaccgagct tccccttggt cttcgtgccg
    15061 tccagggcga tcatttcgtg atcgacggcg gcctgatcca acgcttccat tcccaacaac
    15121 cgcggcgcaa tggctttgct cacattcgca accgccttgg acacgccctt tcccatccaa
    15181 cgcttcttgt cgccatcccg caactcgatc gcttcctttt cacccgtcga ggctcccgag
    15241 ggcaccgccg cccgcccatg cgccccgctt tccaacagca cttcgacttc gaccgtgggg
    15301 ttgcctcgtg aatcaataat ctgccgcgcc ttcacgttcc tgattccgct catgctcgtt
    15361 gtctcctcca ggtactcgca ctcaacaatg actgctgtcg tttcatttcc cgctacctga
    15421 tcccagcctt agcccaaggt ttttttcaac aactcattca ctttgccggg attggccttc
    15481 ccgccggatg ccttcatcac ctgtcccacg agaaagccca gcacctgctg cttgccttcc
    15541 ttaaattgcg ccacctgagc agggtttttc ttcaagactt catcaatgat tgacaccaag
    15601 gccccttcgt ccgatacctg cgtaagcccc ttgtcctgga cgatctgcgc cggcggtttg
    15661 ccagaggcat acatctccgg gaagatgtcc ctggccacct ttaaactcac agcgccttga
    15721 tcgaccatcg tgagcaattc gaccagccgt tccggcgtca cgggtgaggc atcagcctga
    15781 atgccggcat gattcaattc acgcaacagc tcgcccatca cccaattgct gaccgtcttg
    15841 ggatggggat acagcttgac gcacgcatca aaatacacag aaagggcttt gctggatgtc
    15901 agaatccccg cgtcgtattc agggatgcca tactccgcga caaagcgttg ttgcttcgtc
    15961 gaggccaact ccggcaatcc ctcgcgcaat tgttcgatcc aatcggccgc aatctccagc
    16021 gggacgagat ccgggtctgg aaaataccgg tagtcatgcg cttcctcttt gctgcgcatc
    16081 accgccgttt caccgcgctc gtgattccaa agccgggttt cctgatagat cctgcccccc
    16141 tcgttcagca ccttggtctg ccgcttgatt tcgtaatcca ccgcgtcttt cacgaacttg
    16201 aaggaattga tgttcttcaa ctccaccttc gtgccgaacg ccttctggcc aaccggccgc
    16261 aatgagagat tcggttcgca gcgaaagctg ccttcctcca tgttcccatc gcacacgtcg
    16321 agatacatca agagttcacg cagcgctttg agatacgcca cgacttcttc ggaggaactc
    16381 agatccggtt cggtcacgat ctcgagcagc ggcgtcccgg cgcggttgag atcgaccagg
    16441 ctcatgccgc ttccggcttc atgcagattc tttccggcat cctcttccaa atgagcacgc
    16501 cggatccgta cgcgtttccg ggtcccgccg gcagcgattt cgatccaccc atgctcacaa
    16561 atcggcgctt cgtattgaga aatctgatag cccttgggca aatcgggata aaaatagttt
    16621 ttccgggcga agcgattgtg cacgccgatc gtcccgttca tcgccaatcc ggcgcgcacc
    16681 gccatctcca cggctgcctc gttgatcacc ggcaggcttc cgggcaaccc caggcagaca
    16741 gggcatgtct gggaattggc ggttcggcca aacgtagtcc cgcacgggca gaatagcttg
    16801 gactgcgtgc gcaactgcgc atgcacctcc acaccgatga cgacttcgta cgctgcgctc
    16861 aaccctgctc tcccttgctg aactgctcgc gctcccgcct catggcttcg cgccctgcat
    16921 caaaggcctc ccgcaagacg gatttcttcg attcgataaa atcgcgtccc tcttcgacgg
    16981 cgccttcaaa ccgttccccc gcctcgccga ccaaatcccg caacccgtct tccgcacgac
    17041 gcgcatagcc gcgcaacatc tcacgcgact ccggtccggt tcggggcgtc aacaagatcg
    17101 ccgccactgc gcctaatgcc gcaccgctca aaaaccccaa cagaaccgcc gccgacgatg
    17161 gaccgtgatt atccgccatt gtgatgtcct ccctctttca agcgttccgt gaccacttgc
    17221 tttgctgcgc gaagccccgc taccacgctc gccacattgg ccagcaagtt ccccccggaa
    17281 cctcgcacca aactatgcac ctgattgact gattcgccga cttcgcccac ggcatgcagt
    17341 aacacggccg catgctccac cccaccgcgc gcctgttcgg tcagatcgtt caggttttga
    17401 ctcatggccc gcaattccgt caccaggacc ggcaggtcgg tattcatctt cgtcacaagc
    17461 tgctccgctt ccgcagcggt cttgcggacc tgaatcaaaa gcggaacgag gtatccgacc
    17521 aggaccgcaa atgcgatcgc gaccagaata gcagcgactt ccacaatcat gggaactccc
    17581 ttcccggctt accgcaccaa cggctttttg gaccgccagt ttgtcgcctg ctcgtaggca
    17641 tgggccccgc gcaacagggt gtcctcttca aacggccgac cgatcaactg cagtccgatc
    17701 ggcattcccg ctttactgaa tccacagggc aacgagatgg cgggaagacc ggccagattc
    17761 gccgagatcg tatagatgtc ggacaaatac atctgtaacg gatcctgcga cttctccccg
    17821 aacttgaagg ccgtggtcgg ggtcaccgga gtcacgatca gatcaaccgt ctcgaaggcc
    17881 gcgtcaaatt cccggcggat caatgtccgc accgcctgcg cctttccgta gtaggcatcg
    17941 tagtatccgg cgctcaacac ataggtcccc agcatgatcc ggcgtttcac ttccggcccg
    18001 aacccttcgg ctctcgtcct gaggtacata tcgagcagat ccttgctgtc gccggcccgc
    18061 aggccgaatt tcaccccgtc gtaacgggcg agattcgaac tggcctctgc ggtcgcaatg
    18121 acgtagtagg tcgccactgc ggcatccgtg gtcggcaatt tgatctcgcg aatgtcggcg
    18181 cccagttccc gcaacccttc aatggctgtg cgcacggcct gttccacttc agggtcgaga
    18241 ccgtcggcga agtattcggc ggggacgccg accttcaacc gtttcagatc tttccgcttg
    18301 agcgccttga gataatcagg aaccggtacg ttcgccgacg tcgaatcccg tggatcatgg
    18361 cctgcgatcg cgcccaataa gatggccgca tccgtgacat ccttcgtgat ggggccaatc
    18421 tgatcgagag aggatgcgaa cgccaccaac ccgtaccgcg agacccggcc ataggtcggc
    18481 ttcagcccga cgacgccgca aaacgccgcc ggctgccgaa tagatccacc ggtgtccgag
    18541 cccaaggacg ccacacattc atccgccgcg acagctgccg ccgacccgcc gctcgacccg
    18601 ccgggaacag tctggatgtt ccagggatta cggctggccc cgaacgccga attttcggtg
    18661 gaggatccca tcgcgaattc gtccagattc gtcttaccga ccagcagata gttttgcgca
    18721 cgcaatttgg caacaaccgt tgcatcatag ggcggcacga acgattccaa catccgggac
    18781 gcgcaggtcg tgcgtacccc ttcggtgcag atgttgtcct tcaccgccag cggcatggcc
    18841 atcagaggcg tcgttttgcg ccagcctttc aaggactgat caagccgttc ggcctgcgca
    18901 acagccgcct ccttacactg tgtgagatac gcattgacct tgggttcgac atgcgccacc
    18961 cgcagaaagt aggcgcgcac gatttccgtc gcgctcacgt cgccggcggt aaatttccgc
    19021 tgcaactccg ccagcgtcat tttatgtagg accgtcaatg ccatcagcgc ttcgcaacct
    19081 tacgggcaat ccggtttttt ccgtccacca ggatgatctt cggcttatgc cgcttgatct
    19141 cctcgtcgct ataatattcg taacagaaaa taatgatctg atcacccacc gcggccttgc
    19201 gggcagtggg gccgttcagc acgatctcgc ccccgccccg ctttcccttc atggcgtacg
    19261 tcataaaccg ttcgccattg ttgagattgg aacagacgat cgcttcgtac ggaagaatgc
    19321 ctgccgcatc caacagatcc tcatccaccg tgagactgcc ttcatattca agacaggctt
    19381 cggtcaccgt cgctcgatgt atcttcgccc gcaacatttg tcgaaacata gtcggctcgt
    19441 actccttacg tcacttaaga ttcttgaatg attttcggca cccggaaaca ctgcgcctcc
    19501 gcatcggggg cattccccag cgcctgctcc ggcgacagag atgcctgcac ctggtccgga
    19561 cgaaacacat tggtctgccc caacacggtc gaggtcggct ccacatcttc cgtggaaaag
    19621 gacttgagtt tctgaacata gcccacgatc tggttcagct gttgtgaaaa cgccgtcgtt
    19681 tccgcctcgc tcaacgccag gcgcgccagc ttggccactt tctcgacttc ctgcttcgtg
    19741 atctccactc tacacccctc atttaaaccg gtatggtgcg aaggaagggg ctccaattgc
    19801 gcgcgtccaa cgagggcctt ccgaggccgc gcgttgcgcg agcacgggag tccatccttc
    19861 gcacctcatt ccaccgtcac gctcttggcc aggtttcgcg gctgatccac atcttcgcct
    19921 cgcagcacgg caatgtgata cgccagtaac tgcaatggga tcgtgaacaa aatgggcgac
    19981 agcaacggat ggacatcagg aatggtgaac accgcgtcgg cgatcttgcc caactcgcgt
    20041 tcgccttccg ccacaaaagc aatcaccgga gcccggcgcg ccttcacctc catgaggtta
    20101 ctgaccgtct tctcatataa ccggtccctg ggcgccaata ccaccaccgg catatcttta
    20161 tcgatcagcg cgatggggcc gtgcttcatt tcccccgccg catacccttc ggcgtggata
    20221 taggaaattt ctttcaactt cagtgcgcct tcgagcgcaa tgggaaagtt gatgccgcgg
    20281 gccagataca agaagtccgg cttcttatag taccgcttgg caatcgccag aatctccgct
    20341 tcacgaccca gcacatgctt caccagtgcc ggcaccgtga cgaggcgatc cagccaggcc
    20401 ttgccatccg cggcggttaa gacaccccgt acccgaccga ggtgcaaggc caacatgtag
    20461 agcgccgcca actgactggt aaacgccttc gtcgacgcga cgccgatctc agggccacag
    20521 tgggtgtaca acacgccgtc cgattcacgg gcgagggtac tgcccacgac gttgacgatc
    20581 gacacgacgc gcgcgccctt ctgtttggct tcccgggcgg ccgccaatgt gtcagcggtt
    20641 tcccccgatt gtgagatcgt gatgaacagg tcgttttttt cgatcaacgg gtcgcgatac
    20701 cggaattcac tcccgatatc gacctgcacg ggggtacgaa ccatttcctc caacaaatac
    20761 tttcccacca ggccggcatg ccagctggtg ccgcacgcca cgatccagat gcgccccacg
    20821 tcggcgaact gcttcggcgt caggccgata tccggcaaat ccgcctcgcc gctctcgtac
    20881 gagtagcgtc ctcgaatcgt atccagaatg gtttgaggct gctcgtgaat ttccttcagc
    20941 atgaaatggg gatagccgct tttttcagcc gcagacgcat cccaggtaac tttggttttc
    21001 ttgcgcgtga ccgcccgccc gtcgaggtcc gtgaaggtca cacccccggc cgtcacctcg
    21061 gcgacatcgc cctcttcgag gaacgtcacg tccctggtgt gagacaacat cgccatgacg
    21121 tccgagccga caaatgaggc ctccgccgta cgaccgatga ccagcgggca accggatcgg
    21181 gccgcgacga gcaacccggg ctcatgctcc gagatcacgg cgatggcata actcccgcga
    21241 atctccctcg ccgtcgcgcg gaccgcatca gccaggtgca gcttgtcttt tttgatgtgg
    21301 gtatcgatga gatgcgcgac gacttccgta tcggtctcgg actgaaactt gtatccgtct
    21361 ttgatgaggc gctgcttcag ctctacgtag ttttcgatga tgccattgtg cacgagcacg
    21421 cagttctcgg agcggtgcgg atgcgcattc tgctcggagg gctttccgtg cgtcgcccag
    21481 cgggtatggc cgatgccgca catcccggcg atcgccttct gggccagcga gttttgaaga
    21541 ttgatcaact tcccgacact gcgccggatg tcgatctttt ctccgcgctg gatcgccacg
    21601 ccggccgagt cgtaccctcg atactccagc ttcgacaacc cattcaacaa aatcgggact
    21661 gcatcctgat ttcctacgta gccgacaatg ccacacatag ggtgtcgtta cctccgtttc
    21721 gaacgttgaa ctgccggttg cttcttcttg gcggcacggg tccgcggctt tggcttcgat
    21781 gccgccttcg cgggtgttgc actcgcgcgg gccttcaccg ggggcacagg cttcggcgca
    21841 ggaggcggga cctgcccgct ctgcaaggcc cgccgcctgg cagcccatcc ctcacgcgtc
    21901 acctggggca ctcgcgcgat cacgagggca tcggcgggca cgtcttgcgt cacggttgcc
    21961 ccggcggcaa tcacggagcc ctgaccgacc gttaccggcg cgaccaactg cacatcgctg
    22021 ccgatgaaca cgccgtctcc gacgacggtg tgaaatttct tgtacccgtc gtagttgcac
    22081 gtgatcgtac cggcgccgat gttcacgccc tggccgatca tggcatcgcc gagataactc
    22141 aaatggttgg ccttcgagcc ttcgccgagc tccgtcttct tcatctcgac aaagttgccg
    22201 accttcccct tccgccgcac cacgacacca ggccgcaaat ggacgaaggg tccaagatgg
    22261 gagtcgtcct caacctgcga ttcacgaaaa atacaatggt ccagaatctc cacccgctgg
    22321 ccgatggtgc agtccgtaat ccgggtcccg gagtgcacca ccgtattctc cccgatcacc
    22381 gtccggcctt cgagcgttac attgggatac agcagcgtgt cgcgcccgat ggtcacgtcg
    22441 gcgtcgatcc acgcggaggc tggatcgagc atcgtcacgc cggcttccag ccaacgctcc
    22501 cggatccggc ggcgaatgac gccttccgcc tccgccaact gcacgcggct gttgatcccc
    22561 agtccttcgt cgatgtcccg cagacgtaat gccgagacgg tgcgcccctg ctgcacggcc
    22621 atctgcacga tgtcggtgag ataatattcg ccttgcgcat ttcgcggatc gagtttgtcg
    22681 agggccggaa agagaaactc cccgtcgaca acatacgtac ccacgttaat ttcacgcacg
    22741 cttcgctcag cgtgagacgc atccttgtct tccacgatgc tctgcacccg attgtcggcg
    22801 gcaccctgca gccattcttc acgacgatgg cgaatcaccc gcccatagcc cgaggcatca
    22861 tcgagcacgg cggtcaacag cgtcacggcc gcaccttgtg catcatgcat cgcgagcagt
    22921 tcccgcactg tcgcttccgt caacaacggc gtgtcgccgt tcaaaatcag atagcgggtc
    22981 ggtttgcgat gtgcagcatc gccgaatacc ggacgcgctt gcagcaccgc atggccggtt
    23041 cccaactgct tcgtctgctc cgcgaccgcc acctgcccgc cgaccgcttc gacaaccttg
    23101 cgcacatcgg ccccctgatg ccccaccact accgccaccc cctgctcagc caggccacag
    23161 gcaatgtcca gcacgtacag caccatcggt cgaccggcca ccggatgcag cactttggcc
    23221 aaggccgatt tcatgcgctt gccaaggccc gccgccatga tgatgacgcc gagcccggga
    23281 atggaggaag acgaggcatt gtcgtgggat gcgtgagtca tgggtttctc accatacgta
    23341 atcgacacag ggctcgttcg gcggtatcgc gatcaaccga cctgcacgcc tgcatcgggt
    23401 tgcttaatcg gggtccaggt ttttccaccg gcctgcgacc cggcaccaga cggctgcgtc
    23461 ggggtataga gacctcccga cacgatcagc ttcatggcct cttcgaccgt gatatccacc
    23521 gcgatcactt cgcgctcagg caccagcaga aaatagcccg acgtgggatt gggcgaggtc
    23581 ggcacataga catggacgag cgggtccgga gaaagctgtt gcatttcccc tttcgtcaca
    23641 ccggtcacaa aggcaaagca gtaatgcccg ttcttcggaa actgaatcaa caccacacgg
    23701 cgataactct cgcgctccgc gaacgacaga atgtccatca tcgacttaat ggtcgaataa
    23761 attccgcgga ccaccggtac acgattgagc aaactctccc actgccgcac gacctggcgg
    23821 ccgataaaat tcgccgcaaa caatccggtc atgaaaatga gcaggatgag cgcgataatt
    23881 cccagaccgg gcacgtagta gcctggagtt accaaccgtg cggcggcgtc gccgagaatc
    23941 ccatccagac tgacgaacag cgtcttcaga atcaggatgg tgccccagat ggggatcatc
    24001 accagcaaac cggtgagaaa atagcgtttt aatgaagctt gtaccatgcg tggctgaggg
    24061 gtcctgggta gagcgtcatg atactggtct tttgccggtc gtcgcaagcc ttttcttgct
    24121 attttcaatc acttggaata ggatccgccc tctttctccc agaacttttc aggttcgatt
    24181 catgatgaaa cactaccgtc cgccgcgagg gctgttcatt acgctggagg gcatcgaagg
    24241 gtgtggaaaa tccacccagg ccaggctcct cggcgaatac cttcgaagcc agggacacgt
    24301 caccgtcgag acccgtgaac cgggtggaac gccgctggcg gaaaaagtcc gatcagtgct
    24361 gctcgatcgt gccgacgaac cggtggcgcc cgaaaccgaa gcgtttctcg tgctcgccgc
    24421 gcgacgccaa catgtggccc aggtgatcga gcccgcactg gaacagggcg ccatcgtcct
    24481 ctgtgaccgg ttcagcgatt caacgctcgc ctatcagggc tacgcgcgcg ggctgaatgt
    24541 gccgctactg gaacgactca accgcctcgc gactcacgcc gtgatgcctc acctcacgct
    24601 gctcttcgat cttcccgtgg cgacaggact ggcacggcgc cgatctgcca gcgaaacgaa
    24661 tcggctcgat cgcgaatcac tccggttcca ccagaaagtt cgcgccggct tcctcgacct
    24721 ggcgaagcgt catcccgcac ggatcaaagt aattccttcg cgcggatcca aagaaaccgt
    24781 cgcccgcgcc gtggcccgga tcgtcgcacc ggccctgaat cgaatccatc gcgccgacca
    24841 ccagacggct aagccgcgcg ccacatcctc ccacaccaca caggtccgcc atgcccttcg
    24901 ctgatattat cggacacgag cacgccaaga ccctgctgcg atcggcgatc ctgcagaacc
    24961 ggttggcgca tgcgtatctc ttccatggcg atgatcgcat cggcaaacgt ctcctcgctt
    25021 ggcgtttggc gcaaaccctg ctctgcgaga cggtttccga tggccgccag ccggacgcct
    25081 gcggcacctg ccgggcttgt cagcaggtgg atgccaggac gcacccggat tttctggtga
    25141 tcgaaccgga tcaggaaatg gccaatcctc aaattaagat tgagtccatt cgagacatcg
    25201 aacatcaaat gatctaccgt ccgctgatcg gcaatcgcaa aatctgcctg atcgacgagg
    25261 cagaccgcat gaccatcggc gcggcgaatg ccctgctcaa aacgctggaa gaaccaccag
    25321 accacagtct gttcattctc gtgtcgagtc ggccctacgc cttgccggcc accattcgtt
    25381 cacgctgcca ggcgctacga ctcaccgcac cggcacaaac gcaagtcgaa gccgccgtca
    25441 ttttgaaacg cgagctgcct cccgccgatg cgcacttcct cgccttactc agcgacggcc
    25501 aactcgggcg cgcattggaa tgcgatcttg aacaggcgcg caccacccaa aaggaatttg
    25561 cggccatctt ctccgccaag ggacttcagt cgttctcgac cgtcctggct gccgcggaag
    25621 cgctggccaa aggggaccgg ggaccggaag catttgactg gctgcttcgg tggttgcgcg
    25681 acattcttct catcgccgtc ggtgccggct ccgaccatat cctgaacctg gaccaacgag
    25741 ccgggatgca ggcgctggcc gcgcacatca acatcgacga cttgctggat ctcatcggcg
    25801 acctcgaaaa aatggaacga caggcgcacc ggaacctgaa cgtgcagatt gcgctcgaaa
    25861 ccatcctgct cagagtccgt caactcctga ccccgtcagg caccgccgaa cggtcccgct
    25921 aactgagtca tcgcagggag acgcgctgtt gagaacgccg ctggcggcct tctcaacagc
    25981 cagctagctt tgaccatcgg catcttgcta tcttcacccc acaaaccatg agcactcgcg
    26041 acaccttcta catcacgaca ccgatctact acgtcaacga cgtgccgcac atcggtcatg
    26101 cctacaccac cgtcgccgcc gatgtgctcg cgcgctactg gcgattgcgt ggacgcgacg
    26161 tatttttcct gaccggtctc gacgaacacg gacagaaagt gcagcaggcc gccgcgaagg
    26221 ccggcatcga tccccaagcg cactgcgacc gcctcgcacc gcagtttaca aacctctggg
    26281 atcggttgaa catttcccac aacgccttca tccgcaccac cgacaaaccc caccaatccg
    26341 tggttcaacg ataccttcaa cagctcttcg ataagcagtt gatttacaag gcagactaca
    26401 cgggatggta ttgcacgttc gacgaacggt tctggacgga aaaagatgtc gtcggcgggc
    26461 tctgcccgga ctgcaagcgc ccgatcgaac aactgagcga gcacaattat ttcttcaaga
    26521 tgggccagta tcaggaacag ttgcagcggc acatcctgga gcatccggac ttcatccgac
    26581 cggaatcgcg ccgcaacgaa gtcctgggct ttttgcaaac tcaaaagctg ggcgacctct
    26641 cgatctcccg acccaaatcg cgactctcct ggggcatcga acttcccttc gacaaggact
    26701 atgtcaccta cgtctggttc gatgcgctgg tcaattacat ctccgcgctc gaatacctgc
    26761 cgcagggaca accggccgga ttgcgttact ggcccgccga tgtccacctg gtcgggaagg
    26821 atattctcac cacgcatgcc gtgtactggt ccaccatgtt gatagcgctg gagcagccgc
    26881 tgccgaagac gatcttcgcc catgggtggt ggacggtgga tggcgagaag atgtccaaga
    26941 gccgcggcaa cgtcgtcgat ccgaataaga tggtcgacca attcggcacc gatgccttcc
    27001 gctacttcct gctgcgcgaa gtgccgttcg gacaggacgg cgatttttcc cacagcgcgc
    27061 tggtcaccac cgtcaacgcc aaactcgcaa acggcatcgg caacctgctg agccgtacgc
    27121 tcaccatgat cgaacggtcc tgcgccggcg tcatccccga acgaggcccg gcggtgctgc
    27181 cggaactgga acaacgcatt gaagaattgg ccacacaact ccccggcaaa accgaaacgg
    27241 gtttcaacgc cctccagttc cgggacgtgc tgttgatgat tgaagaactc aacggctgct
    27301 gtgacgaata catcgacaag agcgcgccgt ggaaattggc caagcagccg gagacacaac
    27361 cacaattaca tacggtcctg aacacctccg cccgcgccct tcgactgctg gccttgctac
    27421 tctatccctt tatgccaaag gccgccgcgc agatgatcga gcaactggga ttgtcgctag
    27481 acctgtcccg cccgctcgcg gcggaggccg gccgttggga cgcgccgctg gccggcagca
    27541 agattcaaaa aggtgcctcg ttattccccc gcattgaatc caaaccacaa ggagccaaac
    27601 ccgtgagtga tactcccgca tctccgcaac caactgccgc tgccccttca gcagcgcccg
    27661 ctgcaccaca atcccctgct ccggccgcca caccggccgc cgctcctgca cccgcgcagc
    27721 cggcccagat cagcatcgac gacttcatga agattcaact caaggccgcc aaagtgctgg
    27781 cagcggaacg agtgccgaaa tccgagaaat tgctcaagct ccaggtcagc ctcggcaccg
    27841 agcaacggca gatcgtcgcc ggcatcggca agaaatacga accggaagcc ctggtcggca
    27901 aaa
//
LOCUS       DAOQPD010000052        27549 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_790_length_27549_cov_23.143304, whole genome shotgun sequence.
ACCESSION   DAOQPD010000052 DAOQPD010000000
VERSION     DAOQPD010000052.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 27549)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 27549)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27549
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_790_length_27549_cov_23.143304"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(521..1942)
                     /locus_tag="PK063_12420"
     CDS             complement(521..1942)
                     /locus_tag="PK063_12420"
                     /inference="COORDINATES: protein motif:HMM:NF025885.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ97903.1"
                     /translation="MSGAKSKTFTILLVEDNAGDVDLFLRTVEHELPRHEDDEVTLVL
                     NATAEGALERLRQQPIDLVIADVRLPGMSGIELLRQVQDLNRRIPVIILSRVDATETV
                     IDAMRHGAFDYIVEPYDCMDLAARIHRAMRMSEILLQGSPDEPAAPRIPFKNLVGVSP
                     AIRNVMAMIEAIARVPSTTLIIGETGTGKELIAKAIHERSLDSDGPFQVVDCTTFSEG
                     TVESELFGHVRGAFTGAVADRTGLIESGSHGTVFLDEIGDLPATLQAKLLRVLEAGEV
                     RAVGSTQQRKVNVRFVAATNQDLAEKVKRNEFRKDLFFRLNVMVIRVPPLRERTEDIP
                     VLARHFIARYAKEFTKRVDDLHPAAVTELVAYPWPGNVRELRNVMERAVMLAKGDRIG
                     IADVAAMLAVPDERQRDTPDEDYLHLPYAKAKEQVLEAFNRRYISTKLTIHQGNVTHA
                     AQDAGLPRSYFHEIMRRYSKDEK"
     gene            complement(2124..3311)
                     /locus_tag="PK063_12425"
     CDS             complement(2124..3311)
                     /locus_tag="PK063_12425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium:proton antiporter"
                     /protein_id="HMZ97904.1"
                     /translation="MLPVATPEPQESTLLRFPNRNTPPRYDRAIGEWALVIPLGTAGL
                     FFVHGHEWLHDLSNPLRLSAMLAWLLLVIAFSAFAVLRHAEHLAARLGEPMGTVILTL
                     SVTGIEVMMIAAFMYTGNGNASLARDAMFAVVMIVLNGMVGLSLLLGGLRYHEQTYNL
                     QGANAFLAVIVPLAVLGLVMPSYTISSPGPTFSPHQAIFLIVMSLGLYGVFLAIQNLR
                     HRNYFVAPRRQSRRNAAILHEHQPSPGGSVWFHTLLLLAYLLPLVILSEHVATPIDYT
                     LRLWNAPHALGGVLVAGLVLAPESLGAVRAALANQLQRSVNILLGSVLASISLTIPAV
                     LAIGFFTDSTILLGIDPVDTILLVLTFVVSMLTFAVRRTNVLLGAVHLLLFLAYLMLI
                     FEK"
     gene            complement(3353..3667)
                     /gene="sugE"
                     /locus_tag="PK063_12430"
     CDS             complement(3353..3667)
                     /gene="sugE"
                     /locus_tag="PK063_12430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HMZ97905.1"
                     /translation="MAWTFLIVAGLFEICWAIGLKYTDGFSKFWPTAGTLMAMAASFG
                     FLAQALKSIPVGTGYAVWTGIGAAGTAVLGIVLFAESVSIVKVFSLLCIVLGIIGLKG
                     SA"
     gene            complement(3799..>5652)
                     /locus_tag="PK063_12435"
     CDS             complement(3799..>5652)
                     /locus_tag="PK063_12435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HMZ97906.1"
                     /translation="IYRHLSEHRDSREGNVSTILRAAMEVGQPVVFGILIIIIVFFPI
                     LSLQGMEGKMFQPLAYTIIIALLISLLLSLTLSPVLCSLVLKDAREEDTLLLRWIKRA
                     YMPALGWALRHRTVVLGSALVMLAASLALFPFLGGEFIPILNEGSVSPQTIRLPGISL
                     EKSIEIEKEMQRAILEFPEARMVVSKIGRTELGNDPQEPNSSDPVVSLVPMDQWKTAT
                     TKAQLDDAIRRRLQRIPGANFLISQPIQQRVDELVSGVRSEATVKVLGDDLDVLRATA
                     DKIQTIMTGIDGVKDVRVEQLFGQPYLTIDIDRGQIARHGINVAHVREIITTAIGAEP
                     ATRVYEGQRRFDLILRYPEQYRDSVDTVSNILLTTPTGALIPLGNIAKVELREGPALI
                     SREGLQRRIYVGFNTFGRDIESIVHEAQTKIARQVPLPTGYRLQWGGSFENMQRAMAR
                     LKIVVPLTIGVIFLILFSSFNSLRHAALIILNLPFALIGGIAALWLTGEYLSVPASVG
                     FINLFGVAVLNGIVLVSYINKLRAEGMAGEEAVVTGCSLRLRPVLMTAVVALLGLLPL
                     ALSHGIGSEVQRPLAIVVIGGLVSSTLLTLIVLPVLYQWFDRPDKSAAPAN"
     assembly_gap    5653..5752
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<5753..6777)
                     /locus_tag="PK063_12440"
     CDS             complement(<5753..6777)
                     /locus_tag="PK063_12440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HMZ97907.1"
                     /translation="MVSSLLQLALRQRVLVVVIAFALALGGLYAFQTIPIDAFPDVTT
                     VLVQVVTKAPGLSPEEIERFVTFPLELQLTGAPGLVEVRSLSKVGLSMIDVIFEDQVD
                     IYLARQVVLERVLEVQDQLPPGSISQLVPNTTGLGEVFQYVLKGPQDDAAGGLVTEQE
                     LMMRRTLQDWLIRPLLKGLPDVVDVNSLGGFVKQYQVMVDPGLLRKYNLGLHDVFAAV
                     QQNNANAGGNILEKNSERYIVRGVGLIKTVADIEQIVVKEVGGTPVYVRDVAEVRIGS
                     AIRHGAAVINGQQETVTGIVLMLRGGNAREVVQAVKTKIDDIHAHKLLPDGLRIVPFY
                     DRIELITA"
     gene            complement(6782..8011)
                     /locus_tag="PK063_12445"
     CDS             complement(6782..8011)
                     /locus_tag="PK063_12445"
                     /inference="COORDINATES: protein motif:HMM:TIGR01730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HMZ97908.1"
                     /translation="MAAACHDHHAEVSPRHARRWTARGISLLFVVLLASSGCDGPPPN
                     ATGANPPVAPAESGSIRLTAEKVKSAGITVQPLRRGEFRTFRDFPGTVEPDEHALAEI
                     TTLVRGRVIDVYADLGREVKGGTLLALLYSSELGMAQSAYLKATAKLNVADRAFRRAE
                     LLLKEKVIGLAESQRREGEMISLRAEQREARDRLLLLGLTDEDLRHLDKNQTIRSHVP
                     VVAPFDGRIIARNLTKGEVVETTEKLFVLADLSEVWVTAKIPEKDIPYIRTDQTGTGQ
                     LVEVHVSAYPGQIFQGSITYVGDVLDPATRTMRLRLELPNPQRKLKPEMYATVRVYSD
                     PEPNVLLIPETAIQRDRDRQFVFVEREPGLFEIRPVQLGDSNGKEVKVLGGVEDQEAV
                     VVTGSYVLKSELLGSQI"
     gene            complement(8011..9387)
                     /locus_tag="PK063_12450"
     CDS             complement(8011..9387)
                     /locus_tag="PK063_12450"
                     /inference="COORDINATES: protein motif:HMM:NF014385.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HMZ97909.1"
                     /translation="MNRRSPMQWGNDQARFTRGSVNVWHLRLTYHMTIGCLVAMLSGM
                     AWSSPCLSWAASPSTMSSSASEPVYSMATVLDLALARNPTVASAEGTIEQNRGQQVAA
                     HTYLNPSVNANSGRGRMRDLGLFDPAVRESVTEFNLSVGQPIEWPSKRAARQRATEAG
                     VASASAGLAETRLNLIADVKVAFYDLLLAQRDLTLAQQNLATIEDVHRAVTTRVRLGE
                     SPQFEAIRSEVEVLKAKQSLTSANNRMRVGRVMLDTLTAGSLGPSYAIDGQLHRVGPG
                     FGIDILTERALTEHPTIMRLRKAVEQADHSLEFERQARVPNITIGGSYWREIGREAFT
                     GGVSFPTPVWDRRQGEIISAFGSKRKGEAEYLRARNELIRNISQHFQDAKTTADLIEV
                     YEKGLLRQAEEALRIAKFSFQQGASSLIEVLDAQRVQRQILLDYAQAQFDLSISLALL
                     ERAVGGNL"
     gene            complement(10009..10209)
                     /locus_tag="PK063_12455"
     CDS             complement(10009..10209)
                     /locus_tag="PK063_12455"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97910.1"
                     /translation="MSPTATRCQFCWRVEDNRTGGTDSAAWSDLPTFMQKHNLVSHDL
                     NFADGYCPQCTQLYGRLTQEHP"
     gene            complement(10394..11038)
                     /locus_tag="PK063_12460"
     CDS             complement(10394..11038)
                     /locus_tag="PK063_12460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ97911.1"
                     /translation="MTTPPRVLLADDHTLVLEGFRRIVEQRCEVVGAVEDGRALLEAA
                     MQLRPDLILLDISMPLLNGVDAGRQLKKLLPDVKLIFVTMHADPAYVSEAFKAGASAY
                     LLKRSAARELDQAIDAVLKGQYFVTALLTRDIVTGLSAGQSGLFAQRQELTPRQREVL
                     QLIAEGRTIKEIAALLNISPKTVEFHKAQIIFHLNLRTTAELTKYALAHGLTSA"
     gene            complement(11035..>11859)
                     /locus_tag="PK063_12465"
     CDS             complement(11035..>11859)
                     /locus_tag="PK063_12465"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HMZ97912.1"
                     /translation="EIELREAKDELEVRVDARTKELADVNRSLLQEISGHIQTEGFLR
                     NSEQALATSRQELRDLAARLLTVQEEERRRISRDLHDDINQRLAMLVVQAESLEANLP
                     ASAVGCSKELRSIQDRLTELSDDVRHLAYQFHPSILDDLGLPVALQRLVDECAVRSNL
                     AISFETDASPKAIPQTVSTCLYRIAQECLSNIMKHAHASQAKVSLASTAEGITLTVQD
                     DGVGFDTQQVVDNPRGLGLVSMAERVRLVHGTVTIDSIPQQGTRLSIHVPRAEVSV"
     assembly_gap    11860..11959
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<11960..12329)
                     /locus_tag="PK063_12470"
     CDS             complement(<11960..12329)
                     /locus_tag="PK063_12470"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97913.1"
                     /translation="MHDRNHTILPLIIGLSAALFAVDLFMPLGIAIGVLYAGIVTLAA
                     ASSHPRLPFLTAIASTPLIIAGAALGPQHAAIPVWVGVSNRIFSLMIVWISAVLLQQR
                     RRAEIELREAKDELEVRVDAR"
     gene            complement(12406..13800)
                     /locus_tag="PK063_12475"
     CDS             complement(12406..13800)
                     /locus_tag="PK063_12475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ97914.1"
                     /translation="MQATIYVTDDEPAIRSAIVKRLSRRHHTVTGFESGEDLVSAVAQ
                     QAPDLILLDLKMPGMGGIEALRKIRPLAPQTLIIMLTAYGTVENAVEAMRLGAYDFLI
                     KSVDLSGVDPVVDRALEFLALRHRVQFALEDQNSAYALANIDARSPAMQLLLGQVRDV
                     AENAKSTVLLQGETGSGKEFLARVIHCNGPRAAGPFVAVNCTAIPKELFESELFGYER
                     GAFTGAHQRKRGLLEKAEGGTLFLDEIGDLDPAMQAKLLRVLQERTFRRLGGTEDLSV
                     DFRLMTATNRDLKKDTARGTFREDLFFRLNVVTFELPPLRVRAEDILPLCMQAMLRFG
                     KEFGKEVIDIEPDAKELLQRYSYPGNIRELHNIIERAMILCHDKTLTAGCLPRELRDQ
                     ASTHVAVAMAQGEHPSLRIEMVLGQQTLADIESALIEEVVRLSDHNKTLAAKHLGLTR
                     FALDRRLKKQMEHE"
     gene            complement(13772..15727)
                     /locus_tag="PK063_12480"
     CDS             complement(13772..15727)
                     /locus_tag="PK063_12480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ97915.1"
                     /translation="MSDLLSNLPIARKLFLASVIPALTVLLLSILTYRSVTTFSDDEG
                     QLNDIYYSQRLASEYLRLVVDLETGFRGFVLTSQEHYLFPYRTAQDHVLNIGRTLEAQ
                     VSQQDDQRALITSVQQLVKQFISEKEVLIDAVKAEHPNEAREYIEEGKGRALMLKIRQ
                     DMGRFEHLTQTALNTKLAKIAQDRDTMLMTILGGGLFSLICMVAALHLIAHSITTPLA
                     RLATAVVTSDRNPIPQVPVMTRTDEIGNLARVMHAMSTAIHSHIEALQQSEGNLRQLN
                     QDLAGSEAKYRSIVDHAPFGIFTTKGMTLVFSNRYNSLLAGLNSTEEKDPDAVRRAIH
                     PEDRDRVIAEFAQAVVEGEPYETVFRFLHADGTIRKVLSRRIPIRDQSGQVVMYQGFN
                     VDITALDFMQTRLRRAERLATLGQVAAGIAHEIRNPLVGIGSTTSLLLDDTDASDPRR
                     PDLAVILQETKRLDRIVNQIIDYARPREIVAFTFDMAQLVHEVMKVLDEPLTRKQAVI
                     NLSAPAAPYMIQADRDQFKQVLLNILQNAIEATPQGETITVALAEQARGIESGLEITV
                     TDQGSGISPSHLPHVFEPFFTSGKPRGTGLGLAISRNILDAHGGDIALDSEEGRGTTV
                     RVWTPVRQQPQRMQEEGDHAGHDLRYG"
     gene            16145..17017
                     /locus_tag="PK063_12485"
     CDS             16145..17017
                     /locus_tag="PK063_12485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HMZ97916.1"
                     /translation="MDYVKPYGVVDSMLAGGALKLSLPPRQLVLRGMLAGAYLGIGTS
                     MAVTVAVETGYWILGSLVFPFGLALAILLGAEIITGSFALLPVAAAHGQKNAGLSRVF
                     ANWGWVFLGNLLGSVLYATLFAIALTTGGDAPINAVGNKLIAIAQAKTTYYASHGSAG
                     LLAAFTKGMLCNWMVSLAVVAAYMSTSLSGKFVAIWGPTLLFFSQGFEHAVVNMFLMP
                     VGMMLGADVSLSTWWLWNQIPVTLGNLVGGMLFTGLAIYAAHHATAPAAAAAQAPAQP
                     VTARGEQAGYSPSY"
     gene            17036..18634
                     /locus_tag="PK063_12490"
     CDS             17036..18634
                     /locus_tag="PK063_12490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0009410 - response to xenobiotic stimulus
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DHA2 family efflux MFS transporter permease
                     subunit"
                     /protein_id="HMZ97917.1"
                     /translation="MAAVYLRRLHGWRFVLFNAVLGLSHIVVLFNAGSYIALLPHVSG
                     DLGGVLPSFLTWAQTDFMVGLALGFPLARYLSGRIGDYRLLIGAFMVYSVASYLCGDS
                     RTLAQFVPARIVQGIAGGITLPIAQSMLLNEYPKRLKAVALTVWGLFSITPFTIGMPV
                     GGYIAYMLGWRFLFYLDFVLTLVIVGTLGALLYGRGFRRRYARFDLVGFLLLAVLLLG
                     LQTLLNMGNDFDWLDSPFLQVIAVVLLIAFPCFIIWELGERHPTLDLRLFLHRNFVIG
                     IISLTLGFFSIQGLLSLLIVQIQLILGYSSKLAGLALLPLVLLSAPIIAVMHYLCKYV
                     DARWLVCLNCLGFAWTFYWIGLYDDPHSYEELFWPMVVEGIFLGSFFTPITVLTLHGL
                     SGPLVMRAAEVANLLRVAAGAFGITFQGIVLFRRIHFHQLHLADHFGGRQSISYDPMG
                     QLAAKFQAAGLSVSEAQAKLGLVIKQEAAILGLNDAFLVASFIFVGLGGLVWFAHPTH
                     VPIASSPEDDLRVRRAEELIEEVP"
     gene            18631..20139
                     /locus_tag="PK063_12495"
     CDS             18631..20139
                     /locus_tag="PK063_12495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux transporter outer membrane subunit"
                     /protein_id="HMZ97918.1"
                     /translation="MRSGSTVGQRVWRCLGIGCVLLFGSCAWIPKGDPPAQYLDPPEM
                     TETLAEITSRLQNWPDDHWWEQFGNPELNGLIETALKDNPGLKHASARLRQATSLVKV
                     EGARLLPFLEADASLTYERISQHGVFAALNPEVAGIKIMYGIINPLSFRYEFDFWGKN
                     RAMLEGALGHAAAEEAETAEVRLRLTTGIARAYFRGQALQQQLTIVKTIVGIRRDLKN
                     LAETRFRLGLDNDQPFKIAVADYEAAFKRQAAIRDQLDVQRHLLARLAGKGPDEAAHL
                     FAKPMANIPKQIPAPDHLSIGLLVHRPDLAAALYRAHAASRLVRVATTQFYPTIDLTG
                     FVGFNALTLAKGTDKLANFLFSGQSFTYGLAPGLRMPWFEGGRLRGELGAQRAEYDAA
                     VELYNDTLLDAMREVADSLSAWHTTNEIMASHKRLVASLGEDWRLAKVRLVNGLDDDR
                     EVLRHRYPVLEQEYALRALESDQLVAAVDLIESLGGGYHNPDIEKRPKHNPS"
     gene            20144..21691
                     /locus_tag="PK063_12500"
     CDS             20144..21691
                     /locus_tag="PK063_12500"
                     /inference="COORDINATES: protein motif:HMM:NF012739.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HMZ97919.1"
                     /translation="MTTTTADMSQPPQSPGVPPPAGSYRIHPKAIRARRNRRLLVVAL
                     LVLIATVGYLMYWYTHDRFWIRTDNAYVTGNLVPVAAQASGIITQVLAEETQFVNRGD
                     LLVRLDEHQAYAALGRARGRLGEEVRRIAALFINRKQLAEKLRSRMARLELAEHDMDR
                     YQRASPSGAISKQILQNTADKIASLEAEVRETQAELDSLDAQIGGTTVMAHPSVDLAK
                     HQLIEAHLEYARQQIRAPISGYVAKRKAQVGDRVQPGASLMTIVPLDHLWVEANLRET
                     ELQHVRPGQPALVSVSLYGSKQTFHGTVEGLVPGSGSAFALLPPDNSTGNFIHIVERV
                     PVRIALPADELREHPIRPGLSTMTSINITESGQSVWTSLATPSTAEYETDVYADELPT
                     AESMAKEVMATNLVVSENGDGIDSLLEDEGAIERVNPRRDVDRLPNEGKAAPKLDRLR
                     ERDDRRPSSFVPRRSPDLGATTFPLTPSIGPDSRSLGPEAGRNPSRLKPGFGLDDERR
                     AFGSGRR"
     gene            21958..23478
                     /locus_tag="PK063_12505"
     CDS             21958..23478
                     /locus_tag="PK063_12505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HMZ97920.1"
                     /translation="MPNVTLNYRTLLSVTNVLNSQRNRQSLFRAITDQLTKVVRWERA
                     GITVYDLQTDAFRFYAVETNLPKVVLRSDAMIPRAQSAVGWVYDHQRVHVRPHLREER
                     LFIEDESYAQEGLGRMINLPMVVQEACLGTLNIGSIEAGYPDPDDVDFLQQVATQIGF
                     AIAHVNAYEEINRLREQLARENVYLTEELKATQDYGIVAGRSRAFEAVLTLARQAAPT
                     TATVMITGETGTGKEVLARAIHERSLRRERAFVRLNCAALPSGLIESELFGHERGAFT
                     GADHQRVGRFELADGGTLFLDEIGEMPLEAQAKLLRVLQDGMVDRVGSAKPIPVDVRV
                     IAATNANLERAIQQGRFRSDLYYRLNVFPIHMPPLRERPEDIPILARHFLRFHARRLK
                     RLCEDFDASSMERLVQYAWPGNVRELENLVERGLILCHDRWLRIDPAMINLPAASEVN
                     PRRTLVDEERRHILQSLTLLDWRIEGPGGAAEQLGLAPSTLRSRLQKLGIRRPSRC"
     gene            23938..27378
                     /locus_tag="PK063_12510"
     CDS             23938..27378
                     /locus_tag="PK063_12510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HMZ97921.1"
                     /translation="MMQLSRRQFLKASAGTVAVAAVADKALALTALQPVVEVDNPLGE
                     YPDRSWERVYHDQYRYDSSFTWCCSPNDTHACRIRAFVRNGVVMRVEQNYDHQTYEDL
                     YGNRGTFAHNPRMCLKGFTFHRRVYGPYRLKGPLMRKGWKQWMDDGSPELTSDAKRKY
                     KFDSRFLDDMVRVSWDTAFTYVAKGLVVIGTRYSGEAGARRLREQGYAPEMIEMMKGA
                     GVRTFKHRAGMPILGMMGKHANTRFNNCVLPLLDSWIRKVNPDQAQGGRYWNNYTWHG
                     DQDPSQPWWNGTQNCDVDLSDMRFTKLNTSWGKNFVENKMPEAHWKLESIERGARLVV
                     ITPEYNPTASRADYWIPVRPETDGTLFLGASKIILDENYQDIDFIKGFTDMPLLVRTD
                     TLQYLDPFEVVKDYQLPDFSKSYSGRLQGLTQDQIRRLGGMMVWDLAKGKAVPLHREQ
                     VGVHLAQSGIDPALTGTYRVKLLNGREIDAIPIYQMYQIHLQDYDLDTVHQVNRAPKD
                     LIVRWARDCGTVKPAAIHNGEGVCHYFHMTSMGRAAALVMMLTGNIGKFGTGCHTWSG
                     NYKVGIWQAAPWSGAGASVYLGEDPWNLNLKDDVHGKEIKYRKYYYGEEPGYWNHGDN
                     ALIINTPKYGRKVFTGKTHMPSPSKVRWVVNVNILNNAKHHYDMVKNVDPNIEMLVTQ
                     DIEMTSDVNHADVAFAVNSWMEFTYPEMTATVSNPWVQIWKGGIRPLYDTRNDLDSFS
                     GVAAKLKEMTGEQRMADTYKFVYHNRVDVYVQRILDASSTFFGYSADVMLKSEKGWMV
                     MCRTYPRHPLWEETNESKPHWTRSGRLETYRVEPEAIEYGENFISHREGPECTPYLPN
                     AIMTTNPYVRPDDYGIPVTAQHHDDKTVRNIKLPWSEIKQHANPLWEKGYQFYCVTPK
                     TRHRVHSQWSVNDWVQIYESNFGDPYRMDKRTPGVGEHQLHINPQAAKDRGINDGDYV
                     FVDGNPVDRPYRGWKPSDPFYKVSRLMIRAKYNPAYPYHVTMAKHAPYVATAKSVKGH
                     ETRPDGRAIAVDTGYQSNFRYGAQQSFTRNWLMPMHQTDSLPGKHTIAWKFKWGYAID
                     HHGINTVPKECLIRITKAEDGGIGARGPWEPVRTGFTPGQENEFMVKWLKGEHIKIKV
                     "
BASE COUNT         5554 a         7737 c         8283 g         5775 t
ORIGIN      
        1 ttgagaaact gtctccgtga aacggaaacc tgcataatag ctacctcctt gtgagatgca
       61 tgagtccctc atgcacctgt tcgtacaact tcactacact cacgtggatg caatctcgtc
      121 tggtgtaccc cctttccgcg tgtcgaattg gaaacattcg tccctcacaa ttcgaaaatt
      181 tcgagcggac attcgctcgc ggtataggag tattacaatt cacatgccga aaggggagaa
      241 atctggcgct ctttggatgg caatttagtg acgattaatg cagtaaaatc aattgattgc
      301 gtgatggtgt tttcgaggga gttggatggg gaaggaaggc ctgataggca gggtcaggaa
      361 ctactgacta gggagaaagt tcagaggctt aagttgttga tattaaagat gaaggcagtg
      421 tctgtaaatg cggacggcgt catgagatgc atgaaacgtg atttaaaaca atagcttgtg
      481 catctatgtc ggcttttggt gtcatgcttt actgacacca ttatttttcg tccttggaat
      541 accggcgcat gatctcatga aagtatgaac gaggtagtcc agcatcttgg gcggcatgcg
      601 tgacattgcc ctgatggatg gtgagcttcg tggagatata tcgacggttg aacgcttcga
      661 gcacctgttc tttcgccttt gcgtagggca aatggagata atcttcgtcg ggagtatctc
      721 gttgccgttc gtcgggaacg gcgagcatcg cggccacatc tgcaataccg atacgatccc
      781 ccttggcgag catgaccgct cgctccatca cgttgcggag ttcacgcaca tttcccggcc
      841 agggataggc caccagttcc gtcacggccg cgggatggag atcgtccacc cgtttcgtaa
      901 actccttggc ataacgggcg ataaagtgtc gggcaagaac aggaatgtct tccgtccgtt
      961 cccgtagagg cggcacgcgg atgaccatga cgttgaggcg gaaaaacagg tctttgcgga
     1021 actcattccg cttcaccttt tcggccaggt cctgattcgt cgcggcaacg aagcggacat
     1081 tcaccttccg ctgttgggtg ctgccgacgg cacgaacttc accagcctcc aggactcgca
     1141 agagcttggc ttggagagtg gcggggagat cgccgatttc atccaggaag acggtgccgt
     1201 ggcttccgga ttcgatcaag cctgttcggt cggccacggc cccggtaaat gcgcccctga
     1261 cgtgtccgaa gagttcactc tccactgtgc cttccgagaa ggttgtgcaa tcgacgactt
     1321 gaaacggccc atcactatcg aggcttcgct catgaatcgc tttcgcaatc agttccttgc
     1381 ccgtgccggt ttctccaata atgagcgtgg ttgacggaac ccgcgcgatg gcttcaatca
     1441 tcgccatcac gtttctgatc gcggggctca cgcccacaag gtttttgaac gggatacgag
     1501 gggcagccgg ttcgtcgggc gagccctgga gaagaatttc cgacatgcgc atggctcggt
     1561 ggatacgggc cgccagatcc atgcagtcgt atggttcaac gatatagtcg aacgcgccgt
     1621 gacgcatcgc atcaatgacg gtctccgtgg cgtcgacgcg gctgagaatg atgaccggga
     1681 tacgccgatt caaatcctgc acttgccgaa ggagttcgat accgctcatg cccggcaagc
     1741 gcacatcggc gatcacgaga tcgatgggct gctgccgcag acgttcgagc gcaccttcgg
     1801 ctgtggcgtt gaggacgagc gtcacttcat cgtcttcatg gcggggcagt tcgtgctcga
     1861 ccgtgcgtaa gaatagatcg acgtctcccg cgttgtcttc gacgagcagg atcgtgaacg
     1921 tttttgattt ggcgcctgac atgcgtgtct tttcagaaaa cactgacaat ccgccgagga
     1981 actcggaatg tgaaacctgt ccagcgtgga tctgattggc cttcaattcc cggcgtaact
     2041 ggccgcctct cgcccgtatc ttaggaggcg aaggcgcggc aaatcaaccc ggcggcttat
     2101 tcggagggag accgattttt cggttatttc tcaaaaatca gcatgagata agccaggaac
     2161 aggagcaggt gaacggcgcc aaggagaaca ttcgtgcgtc tgacggcaaa ggtgagcatg
     2221 cttaccacaa acgtgaggac caggaggatg gtatcaaccg gatcgatacc gagcaggatc
     2281 gtcgagtcgg taaagaagcc gatggccagc actgccggaa tggtgaggct gatgctggcg
     2341 agcactgatc ccagaaggat attgaccgaa cgttgcagct ggttggccag cgcggcccgc
     2401 acggcaccga gcgattccgg cgccagcacc aaaccggcaa ccaggacacc tcccaaggca
     2461 tgaggagcat tccaaagtcg tagcgtgtag tcgatgggcg ttgccacatg ttctgagagg
     2521 attactagcg gcagcaggta tgccagaagc agcagtgtat gaaaccacac ggagcctccc
     2581 ggggaaggct ggtgttcatg caggattgcc gcgttgcgtc tgctctgtct gcgcggcgcc
     2641 acgaaatagt tacgatgacg gaggttctgg atcgcgagaa atacgccata gagtccgagc
     2701 gacatcacga tgagaaagat ggcttgatgt ggtgaaaagg tcgggcccgg ggaggaaatc
     2761 gtataactcg gcatgacgag ccccagcacc gcgagcggga cgatgacggc gagaaaggca
     2821 ttggctccct gcaaattgta cgtctgttcg tgatagcgca atccgccgag aaggagtgac
     2881 aggccgacca ttccgttcag cacgatcatc accacggcaa acatcgcatc tctcgccaac
     2941 gaggcgttgc cattacccgt atacataaag gcggcgatca tcatgacctc gatcccggtc
     3001 acggacaagg tcaggatgac ggtccccatc ggttctccaa ggcgggcggc aagatgttct
     3061 gcatgacgaa gcaccgcaaa ggcggagaag gcgatcacaa gcagcagcca ggcgagcatg
     3121 gcgctcaatc gaagcgggtt cgagagatca tgcagccact catgaccatg aacgaaaaag
     3181 agtccggcag ttccgagggg aatgaccaaa gcccactcgc cgatcgcccg gtcataccga
     3241 ggcggcgtat tccggttcgg aaaccgcaac agcgtcgact cctgcggttc gggggtggcg
     3301 acgggtaaca tggacctgta gacctcagtg agagtgggcg ccacctctgt ggtcaggcgc
     3361 tgcctttgag cccgatgatc ccgagtacga tacaaaggag agaaaacact ttcacgatgg
     3421 agacggactc tgcgaagagt acaatcccta acacggcggt accggccgct ccgatgccgg
     3481 tccagactgc gtaccctgtt cccaccggaa tactttttaa ggcctgagcc aggaagccga
     3541 aactggcggc catagccatc aacgtccccg ccgttggcca gaatttcgaa aacccatccg
     3601 tatatttcag cccgatggcc cagcagattt caaacagtcc ggccacaatc agaaacgtcc
     3661 atgccataga atccacatgc tccctgcgcc atcgcgagat gggaaaagtt cagactacgt
     3721 atgatacagg accatccgca gtaagaaacc tcggcatttc actagggaca tagagcaaat
     3781 gcgcgaagag aacgacgtct aatttgcagg ggcggccgat ttgtccggcc gatcgaacca
     3841 ttggtagagc acagggagga cgatcaaggt gaggagggtg gaactgacga gtcctccgat
     3901 cacgacgata gccaagggac gttgtacctc cgacccgatc ccgtgagaca gtgcaagcgg
     3961 cagcaatccc aacaatgcca ccacggccgt catcaagacc gggcgcaggc gcagcgagca
     4021 accggtgacc acggcttcct caccggccat cccttcagcg cggagtttat tgatgtacga
     4081 gacaagcacg atgccgttca agacggccac gccgaagaga ttgatgaacc cgacggaggc
     4141 cggcacactg aggtactcgc cggtcagcca cagcgcggcg attccgccga tgagggcaaa
     4201 tggaaggttc aggataatca acgccgcatg gcgcagcgaa ttgaacgagg agaacagaat
     4261 caggaagatg acgccgatcg tcagcggcac cacgatcttc aaccgcgcca tggcccgttg
     4321 catgttctcg aaggacccgc cccattgcag ccgatagccg gtgggcagcg gaacctgtcg
     4381 cgcaatcttc gtctgtgctt catgcacgat actttcaatg tcgcgaccga aggtgttgaa
     4441 gccgacgtag attctccgtt gcaggccttc ccggctgatc agcgccggcc cctcgcgtaa
     4501 ctccaccttg gcgatgtttc ccagcggaat gagcgccccg gtaggggtgg tcagaagaat
     4561 gttgctcacc gtgtccacgc tatcgcgata ttgctcggga tagcgcagga tgaggtcgaa
     4621 gcgccgctgc ccttcataga cgcgcgtcgc gggctctgcg ccgatcgccg tcgtgatgat
     4681 ttcgcgcacg tgggcgacgt tgatcccatg tcgggcgatt tggccgcggt cgatgtcgat
     4741 ggtgaggtag ggttgcccga ataactgttc cacccgcacg tcctttacgc cgtctatgcc
     4801 ggtcatgatc gtttggatct tatcggctgt ggcgcgcaag acgtccaggt cgtcgccaag
     4861 caccttcacg gtcgcctccg accggactcc ggaaaccaat tcatcgactc gttgctggat
     4921 cggctggctg atcaggaaat tcgccccggg aatacgttgc agccgacgcc ggatggcgtc
     4981 atcgagttgc gccttggtgg tggcggtttt ccattgatcc ataggcacga gggacacgac
     5041 cggatcgctg gagttgggtt cttgagggtc gttgcccagt tcagtgcgtc cgattttgga
     5101 gaccaccatc ctggcctccg ggaattccag gatcgctcgc tgcatctcct tctcgatctc
     5161 gatggatttt tccagcgaga taccgggaag acgaatcgtc tgcggtgaga cggacccttc
     5221 attgaggatc gggatgaact cgccgcccag aaaaggaaac agggccagac tggcggccag
     5281 catcaccaga gccgagccga ggaccaccgt gcgatgacgg agagcccagc cgagcgcagg
     5341 catatatgcg cgtttaatcc aacgcaacag cagcgtgtct tcctccctgg cgtctttgag
     5401 caccagtgaa cagagcaccg gcgagagggt aagcgaaaga agcagggaaa tcaggagcgc
     5461 gatgatgatg gtgtaggcca acggttgaaa cattttcccc tccatgccct ggagggaaag
     5521 gatgggaaaa aagactatga tgatgatcag gatgccgaac acgaccggct gtcccacttc
     5581 catcgcagcc cgcaggatcg tcgacacatt tccttcgcgc gagtcacggt gttccgacaa
     5641 atgccgataa atnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nngcggtgat
     5761 taattcaatc cggtcgtaaa acggcacgat gcgcagtccg tcaggaagca gcttgtgcgc
     5821 atggatgtcg tcgatttttg ttttgacggc ttgcacgact tcccgtgcgt ttccgccgcg
     5881 aagcatgagc acgattcccg tgacggtttc ctgttggccg ttgatcacgg ccgcgccgtg
     5941 gcgaatggcg ctgccgatgc gcacttccgc gacgtcccgg acataaaccg gcgtgccgcc
     6001 gacttccttc acgacgatct gctcgatgtc cgccacggtc ttgatgagcc cgacacctcg
     6061 cacgatatag cgctcggagt ttttctcgag aatgttcccg cctgcgttgg cattgttttg
     6121 ttgaactgcc gcgaagacgt catgcaatcc aaggttgtat ttccgcagca ggccagggtc
     6181 caccatgacc tggtactgtt tgacaaagcc ccccagcgag ttgacgtcca cgacgtccgg
     6241 cagccctttc aggagaggcc ggatcagcca gtcctgcagt gtccggcgca tcatgagttc
     6301 ctgctccgtg acgaggccgc ctgccgcatc atcctgcggg cctttcagga catactggaa
     6361 gacctcgccg aggccggtgg tattgggcac taattgagag atggagccgg gcggcagctg
     6421 gtcctggacc tccagcaccc gttccagcac gacctggcgt gccaggtaaa tatcgacctg
     6481 gtcctcgaag atgacatcga tcatcgagag gccgaccttg gagagcgagc gcacctcgac
     6541 gaggccaggg gctccggtca gctggagttc aagggggaag gtgacgaacc gttcgatctc
     6601 ttccggggat agtcccggcg ctttggtcac gacctggacc agcacggtgg tgacgtcggg
     6661 gaaggcatcg atcggaatcg tctggaaggc atagagcccg ccgagggcga gtgcgaaggc
     6721 gatgacgacg accagaacac gttggcggag ggccagctgc agcagagagg ataccatgtc
     6781 gtcagatctg cgatcccaac aactcggatt tgagcacgta ggatcctgtg acgaccaccg
     6841 cctcctggtc ctcgacgccg ccgagcacct tgacctcttt cccattcgaa tcgccgagct
     6901 gcaccggtcg tatttcgaac agccccggct cacgctcaac gaagacaaat tggcggtccc
     6961 ggtcgcgttg gatggcggtt tccggaatga gcagcacgtt gggctccgga tccgagtaca
     7021 cccgcaccgt tgcgtacatc tcgggcttga gttttcgttg ggggtttggt agctcaagtc
     7081 ggagccgcat ggtgcgcgtc gcagggtcga gcacgtcccc cacataggtg atactgccct
     7141 ggaagatttg tccagggtag gcggagacat gcacctcgac caattggccc gttcccgtct
     7201 ggtcggtgcg gatatacgga atgtcctttt caggaatttt cgccgtcacc cagacctcgg
     7261 agaggtcggc aaggacgaac agtttttccg tagtttcgac gacttcgcct ttggtcagat
     7321 tcctcgcaat aatacggccg tcgaatgggg ccaccactgg aacgtgggat cggatcgtct
     7381 ggttcttgtc caagtgccgc aagtcttcat cggtcaatcc caacaagagc aagcgatccc
     7441 gggcttcccg ttgttcggcg cggagactga tcatttctcc ttcacgccgt tgagattcgg
     7501 ccagcccgat gaccttttcc ttcaggagca gttcagcccg gcgaaacgcc cgatcggcga
     7561 cgttcagctt agccgttgcc ttgagatagg cagactgtgc catgcccagc tcgctgctat
     7621 agaggagggc cagcagcgtg ccgcccttca cctcccggcc caaatctgca tacacgtcga
     7681 tgacgcgccc gcgaacgagg gtggtgattt cggcgagcgc gtgttcgtct ggttccaccg
     7741 tgccggggaa atcccggaag gtccggaatt cgccgcgccg gagcggttgc acggtgatcc
     7801 ctgccgattt gactttttcg gccgtcaaac gaatcgaacc gctttccgca ggggcgacag
     7861 gcgggtttgc gcccgtggcg ttcggcggcg ggccgtcgca tcctgacgag gccagcagta
     7921 caacgaagag cagcgaaatg ccgcgcgctg tccaccgccg ggcgtgcctc ggcgaaacct
     7981 cagcgtggtg atcgtgacaa gcggctgcca ttacaaattc cctcccacag cgcgctccaa
     8041 tagcgcgagc gatatggaaa gatcgaattg agcctgagca tagtccagca aaatctggcg
     8101 ctggacgcgt tgggcgtcca gaacttcgat caggctggat gcgccctgtt gaaaactgaa
     8161 cttggcgatc cggagagctt cttcagcctg gcggagaagc cccttttcat agacctcgat
     8221 gaggtccgcc gtcgtttttg catcttggaa atgttggctg atattccgga tgagttcatt
     8281 acgggcccgc aggtattcgg cctcaccctt ccgcttgctt ccgaaggcgg agatgatttc
     8341 accttgccgc cggtcccaca cgggtgtcgg gaatgacacg ccgccggtaa acgcttctcg
     8401 cccgatttcc cgccagtagc tgcccccgat cgtaatgttc ggcacacggg cctgccgttc
     8461 gaattccaga ctatggtcgg cctgctcgac ggcctttcgc aatcgcatga tcgtgggatg
     8521 ttctgtcagc gcgcgttcgg tgaggatgtc gatgccgaat cccgggccga cacggtgcag
     8581 ctggccgtca atggcatagc tggggccaag ggacccggcc gtcagggtat ccagcatgac
     8641 gcgacccacg cgcatgcggt tgttggcgct ggtgagcgac tgcttggcct tgaggacttc
     8701 cacttcagaa cgaatcgctt cgaactgcgg gctttctccc aaacgcaccc gcgtggtgac
     8761 ggcccgatgt acgtcttcaa tcgttgccaa attttgctgc gcgagggtga ggtcgcgttg
     8821 cgccaggagg aggtcgtaga acgcgacttt gacgtcggcg atcagattca gccgggtttc
     8881 cgccaatccg gctgacgcac tcgcgacgcc ggcttctgtg gcacgctgcc gcgcggcgcg
     8941 tttggacggc cattcgatcg gttgccccac gctcagattg aattcggtga ccgattcacg
     9001 cacggcggga tcgaacagcc ccagatctcg cattctgccg cgtccgctat tcgcgttgac
     9061 cgaaggattg aggtaagtgt gggcggcgac ctgttggccg cggttttgtt cgatggtccc
     9121 ttccgcgctc gccactgtcg ggttccgtgc caaggccaga tccaacacag tggccatgga
     9181 atagaccggt tcagaggctg aagaggacat ggtcgaaggg gaggcggccc aactcagaca
     9241 cgggctcgac caggccattc ccgacagcat cgccaccagg cagccgatcg tcatgtgata
     9301 cgtgagacgc aggtgccaga cattgacgct tcctcttgtg aaccgagcct gatcgtttcc
     9361 ccactgcatc ggtgatcgcc tattcattgc gaaatcacaa tctccttgtt tctgccacgc
     9421 ttggcgccct ctgcgtcgtc tcgcatcgtt cctcgtcaac atgtctccct ccgcaccgtc
     9481 ttgcgccacc gcctgtggcg gcgctgcatc aaatgcacac ggtctctttc aagtaccgta
     9541 tcagcttgac ggagtgaagt ctaacgagcg acccgcgatg tcaaggatca gcgagtaatg
     9601 gaggccaggt cagtggttcc agcgagcaaa cagactgtgt ggtgtaggag gggactcccg
     9661 atgactcgtg ttctagcgag tccagtactg tgtgacttac ggagctgacc tggcgaagac
     9721 actacccggt gcgtcggttc ggatgacgcg ctccgtgcca ctgatagcgg gcctccggtt
     9781 gcgggcgggc gcgagaggcc cgtctcctat accggctgac gatgcgattc gagaagggtc
     9841 gaggttggtc actgttggta tctgcatcgg tgtccgaacc tgtattacgc tcagatccgc
     9901 ttgtggtgca ctcactcgag tgacaccggc gccacctcga aggatgttct cgattgttgt
     9961 tcattccgcg aatgatcctt attcctcgtc cggcccgcat ggccacgtct acggatgttc
    10021 ttgtgtgaga cgaccgtaga gttgcgtgca ctgcgggcaa tatccgtctg caaaattcag
    10081 atcgtgagaa accagattat gtttctgcat gaaggtcggc aggtcagacc aggcggctga
    10141 atcggtcccg ccggttcgat tgtcttcaac ccgccagcaa aactgacatc gtgtggctgt
    10201 tgggctcatg ttcccgctct cctgcagtag tgtccggagt gtggcggaag cgcctctgat
    10261 caggcctcgc tgatcgccac caccatagcg aatgtggtgc gcggtcacaa ctaggtgatg
    10321 tcctaggtgg aggtcagacg cgtcgatgcg acgggttcga agggctgtcg tgtggcggtt
    10381 gcaaaaggtc gcgctaggcg gaggtcaatc catgcgccag ggcatatttc gtcaactccg
    10441 ccgtggtgcg gagattgaga tggaaaataa tctgtgcttt atgaaactcg acggttttgg
    10501 gagagatgtt caagagcgcc gcgatttctt taatggtgcg tccttcggca atgagctgca
    10561 gcacttcacg ctggcgcggc gtcaattcct gccgttgcgc aaagaggccg ctctgcccag
    10621 cggagagccc ggtcacaata tcccgcgtca gcagcgcagt cacaaaatac tgtcccttca
    10681 agactgcatc gatggcctgg tccaactctc gggcggcgga acgtttcaag agataggcgg
    10741 aggcgccggc tttgaaggct tcactgacgt acgccggatc ggcatgcatc gtgacgaaga
    10801 tcagttttac gtccgggagg agtttcttca actgtcgtcc cgcgtcgact ccgttgagca
    10861 gtggcatgga aatgtcgagc agaatgagat cgggacgcag ctgcatggcg gcttcgagga
    10921 gggcccgccc gtcttccacc gcgcctacga cttcgcagcg ctgttcaacg attcgccgaa
    10981 atccttccaa caccagggta tggtcgtcgg ccaggagtac tcgaggtggg gtcgtcatac
    11041 ggaaacctcc gcgcgcggaa cgtgaattga gaggcgagtg ccttgttgag ggattgaatc
    11101 gatggtcacg gtgccatgaa cgaggcgcac ccgttcggcc atgctcacca ggccgaggcc
    11161 gcgcggattg tcgaccacct gctgtgtatc gaatccgacg ccgtcatcct gaacggtgag
    11221 ggtgatccct tcagctgtcg aggccaacga gacctttgcc tgcgaggcat gggcatgttt
    11281 cataatattg gacaggcatt cctgagcgat gcgatagaga caggtcgaca ccgtctgagg
    11341 aatggctttc ggagacgcat cggtttcaaa tgaaatggcc aggttcgagc ggaccgcgca
    11401 ctcgtcaacc aggcgctgca atgccaccgg aagtccgagg tcgtccaata tggacggatg
    11461 aaattgatag gccaagtgac gaacatcgtc ggagagctcg gtcaaccggt cctggatcga
    11521 gcgaagttct ttgctgcagc cgacagcgga cgccggaaga ttggcttcta acgattcggc
    11581 ctggacgacg agcatggcca ggcgctggtt gatgtcatcg tgcaggtctc tcgagatgcg
    11641 tcggcgttct tcttcctgga cggtcagcag gcgggcggca aggtcgcgca gctcctggcg
    11701 actggtcgcg agggcctgtt cgctgttacg gagaaatcct tctgtttgga tgtgcccgga
    11761 aatttcctgc aggaggctgc gattgacatc agccagttcc ttggtacggg catctactcg
    11821 cacctccaat tcatccttgg cctcgcgtag ttcaatctcn nnnnnnnnnn nnnnnnnnnn
    11881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11941 nnnnnnnnnn nnnnnnnnnt acgggcatct actcgcacct ccaattcatc cttggcctcg
    12001 cgtagttcaa tctcggccct tcgccgctgt tgcagcagca cggcggaaat ccagacaatc
    12061 atcagactga agatgcgatt gctgacaccg acccacacag ggatggcggc atgctgcggg
    12121 cccagcgccg caccggcgat aatcaatggc gtggaggcaa tcgcggtgag gaacggtaac
    12181 cgtgggtgag aggaggcggc cgccagagtc acgattccgg catagagcac tccgattgct
    12241 atgccgagcg gcatgaacag atctaccgcg aacagcgcgg cactcaagcc gatgatgagg
    12301 ggaagaatgg tgtgattgcg atcatgcatc gcagacccgt cgtgtcctca ttatctgctt
    12361 cccggctgat tgctgcaacg gcagaccgcg cggtgtgccg gcgatctact cgtgctccat
    12421 ctgttttttt agccgccgat ccagggcaaa cctggtcaac cccaaatgct tggctgccaa
    12481 ggttttgtta tggtccgaca ggcgcaccac ttcttcaatc aatgccgatt cgatatccgc
    12541 cagtgtctgt tgtcccagca ccatctcaat gcggagcgag ggatgttcgc cttgtgccat
    12601 ggctaccgcc acatgcgtcg aagcctgatc gcgaagctca cgcggaaggc acccggcggt
    12661 caaggtctta tcgtgacaca gaatcatggc tcgttcgatg atattgtgca attcgcgaat
    12721 gttgccggga tagctatagc gctgcagcaa ttccttggca tcgggttcga tgtcgatgac
    12781 ttctttgccg aactctttcc cgaaccgcaa catggcctgc atgcaaaggg gaagaatgtc
    12841 ttccgcgcgt acgcgcaacg gaggaagttc gaaggtcacg acgttcagcc ggaagaagag
    12901 gtcttcgcgg aaggtgccgc gagccgtgtc tttcttgaga tcacgattgg tcgcggtcat
    12961 caaccgaaaa tcgaccgaca ggtcctccgt gccgcccagg cgccggaagg tccgctcctg
    13021 cagcacgcgc agtaatttgg cctgcatggc cgggtctaag tcgccgatct cgtccagaaa
    13081 gagcgttccc ccttctgcct tctccaggag tcctcgcttc cgttggtgtg cgccggtaaa
    13141 ggcgcctcgt tcatagccga acagctcgct ttcgaacagc tctttgggaa tggcggtgca
    13201 gttgacggcc acgaacggac cggcggcacg tggcccgtta cagtgaatga cgcgcgccag
    13261 aaattctttc ccgctgcccg tttctccttg gagtaatacg gttgatttgg cgttttcggc
    13321 cacatctcga acctggccga gcagcagttg catcgccgga ctgcgggcat cgatattggc
    13381 cagggcgtag gcgctgttct gatcctcgag tgcaaattga acgcggtgcc gcagcgcgag
    13441 aaattccaag gcgcgatcga cgacgggatc gaccccggag agatcgacgg acttgatcag
    13501 aaagtcgtag gcgcccaagc gcatggcttc gacggcgttt tcgaccgtcc catacgcggt
    13561 cagcatgatg atgagcgtct gcggggcaag cgggcggatt tttcgcagtg cctcgatgcc
    13621 gcccatgccg ggcattttga gatccaggag aatgaggtcg ggggcctgct gcgcgacggc
    13681 actgaccagg tcttctccgg attcaaagcc ggtaaccgta tggtggcgcc gtgaaaggcg
    13741 tttgacgata gcggagcgaa tcgccggttc gtcatccgta acgtagatcg tggcctgcat
    13801 ggtccccttc ttcctgcatt cgttgcggct gttggcgcac gggcgtccac acgcgaacgg
    13861 tggtgccgcg tccctcttca ctgtccaggg cgatgtctcc tccgtgcgcg tcgagaatat
    13921 tgcgggagat cgccaatccc aagcccgttc cgcgcggctt cccactggta aagaacggtt
    13981 cgaagacgtg tggcagatga ctgggactga tgccgctgcc ctggtccgtc acggtaattt
    14041 ccagccccga ttctattccg cgtgcctgtt ccgccagggc gacggtaatg gtctcgcctt
    14101 gtggcgtggc ttcgatggcg ttctgcagga tattgagcaa cacctgttta aactgatcgc
    14161 ggtcggcctg gatcatatag ggagcggcag gggcagaaag gttaatgact gcctgtttcc
    14221 gcgtcagagg ttcgtccagg accttcatca cttcatgcac cagctgtgcc atgtcgaagg
    14281 taaacgccac gatttccctg gggcgggcat agtcaatgat ctggttgacg atccgatcca
    14341 gccgtttcgt ttcctggaga atgaccgcca ggtccggccg ccgaggatca gacgcatcgg
    14401 tgtcgtcgag cagcagcgag gtggttgagc cgatgccgac aagggggttc cggatctcat
    14461 gtgcaatgcc cgccgccacc tgtccgagag tcgctagacg ctcggcccgg cgcaggcggg
    14521 tttgcatgaa gtcgagcgcg gtaatgtcca cgttgaatcc ctgatacatg acgacctgtc
    14581 cggactgatc acgaatcggg atacgccggc tcagaacttt gcggatcgta ccgtctgcat
    14641 ggagaaaccg gaacacggtt tcgtagggtt ctccttccac caccgcctgg gcgaattccg
    14701 caatgacccg gtcccgatcc tccgggtgaa tggcacgccg caccgcatcg ggatcttttt
    14761 cttccgtcga attcagtccg gcaagcaaac tattgtagcg attgctgaag accagcgtca
    14821 tccctttggt ggtgaagatg ccgaacggcg catggtcgac gatgctccga tacttggctt
    14881 ccgacccggc caggtcctga ttgagctggc gcaagttgcc ctccgattgt tgcagggcct
    14941 caatgtgaga atggatggcc gtactcatgg cgtgcatgac ccgcgccaga ttgccgattt
    15001 catccgtcct cgtcatgacg ggaacctgcg ggatcgggtt gcggtctgag gtgaccactg
    15061 ccgtggccag gcgggccagc ggggtggtga tggaatgggc gatcaggtgc aacgccgcca
    15121 ccatgcagat caaggaaaag agtccgccgc ccaggatggt catcagcatc gtgtcgcggt
    15181 cctgcgcgat cttcgccagc ttggtattca gcgcagtctg cgtgagatgt tcgaatcggc
    15241 ccatgtcctg gcggatcttc aacatcagcg cccggccttt gccctcctcg atatactccc
    15301 gcgcttcgtt gggatgctcg gccttcacgg catcgatgag cacttccttc tcactgatga
    15361 actgtttgac caattgctgc acagaagtaa tgagcgcccg ttgatcgtcc tgttgggaca
    15421 cctgagcttc caacgtgcgg ccgatgttca ggacgtggtc ttgcgcggtg cgatagggga
    15481 acaggtaatg ctcctggctc gtcagcacaa agccccggaa tcccgtttcc agatcgacca
    15541 ccaggcgaag gtattccgag gccagccgtt gggaatagta gatgtcgttt aattgacctt
    15601 cgtcgtcgga aaaagtcgtg acgctacggt aggtcaagat gctgagcagc aggacggtga
    15661 gcgcaggaat caccgacgca aggaataact tgcgggcgat gggtagattg cttaacagat
    15721 cactcaaggc agatctcagt ctccgtcgct atcgtagtct gcactcccac cactgtgcaa
    15781 ctttgcagcc tgattgtcgt cctgagtggg cgctcacgcc ggtgaccctt cttatcgcct
    15841 gcggttgttg tttcactcct tcctccagcg ttcaaagctg ccgccgcgca gaggaatgag
    15901 cgatttcgca ccgtgcgccc gtgcgatccc gcccgtctcc acgctggttt cacgcgtcat
    15961 gcgattgtgc gaacggctgc gctggcagat gcggcacgtc accattcgtt gtcgtggcga
    16021 cggcctgaac gggctgttct agatgaggca tgcgccttgc tcaggtcgac tatcgtcaag
    16081 tctcggtgac cgggtcggtg aatcgcggag tgcgcggaat ggcagaccga acaaggagga
    16141 gacaatggac tatgtgaagc cgtacggcgt cgtcgacagc atgttggccg gtggcgcact
    16201 gaagctgagt ttacccccgc ggcaacttgt gctgcgtggc atgttggccg gtgcctatct
    16261 cgggatcggg acgagcatgg ccgtgacggt ggccgtcgaa accggttatt ggatcctcgg
    16321 cagtctggtc tttccgttcg gattggcctt ggccattctg ctcggcgcgg agatcatcac
    16381 cggcagcttc gcgttattgc ctgtcgcggc ggcacacggt caaaagaacg ccgggctctc
    16441 ccgtgtcttt gccaattggg gatgggtgtt cctcggtaat ctcctcggca gcgtgctcta
    16501 tgcgacgttg ttcgcgattg cgctgacaac ggggggcgat gcgcccatca atgcggtcgg
    16561 caataaattg atcgccatcg cgcaggcgaa aacgacttac tacgcatcgc acggttccgc
    16621 gggtcttctg gcggcattta ccaagggcat gttgtgcaac tggatggtca gtctcgccgt
    16681 ggttgcagcc tatatgtcga catcgttgtc cggcaagttt gtcgcgatct ggggtccgac
    16741 gctcttgttc ttctctcagg gttttgaaca tgccgtggtc aacatgtttt tgatgccggt
    16801 gggcatgatg ctcggcgcgg atgtgagcct ctccacctgg tggctctgga atcagattcc
    16861 cgtcacgctg ggtaatctgg tcggcggcat gctgtttacg ggattggcga tttacgcggc
    16921 gcatcacgcg accgcgccgg ctgccgccgc agctcaggcg ccggctcagc ctgtgactgc
    16981 ccgcggcgag caggcgggat attccccgtc gtattagcag tgagggaacg tcgtcatggc
    17041 tgcggtgtat ctcaggcgat tacatggatg gcgattcgtg ctcttcaatg ccgtcctcgg
    17101 cttgtcgcac atcgtcgtct tgttcaacgc cggctcctac atcgcgctgt tgccgcatgt
    17161 ctcaggggat ctcggcgggg tgctgccgag ttttctgacc tgggcgcaaa ccgatttcat
    17221 ggtcgggctg gcattgggct ttccgctcgc gcggtacctg tcgggacgga tcggcgacta
    17281 ccgtctcctg atcggcgcgt tcatggtgta tagcgtggcc tcctatctgt gcggcgatag
    17341 tcgaacgctc gctcaattcg ttcctgcccg tatcgtccaa ggcatcgccg gtggcatcac
    17401 cctgccgatt gcccaatcca tgcttctcaa cgaatacccc aaacggctca aggctgtggc
    17461 tctgaccgtc tggggactgt tcagcatcac accctttacc atcggcatgc cggtgggcgg
    17521 ctacatcgcc tacatgctcg ggtggcgctt cctgttttat ctggatttcg tgctgacgct
    17581 ggtgattgtc ggcacgttgg gtgctctgtt gtacggccgc ggcttccgtc gacggtatgc
    17641 tcgcttcgac ctggtcgggt ttctgctgct ggccgtcctg ttgttggggc tgcaaacgtt
    17701 gctcaacatg ggcaacgatt tcgactggtt ggactcgccc ttccttcaag tgattgcggt
    17761 ggtgctgcta atcgcctttc cctgtttcat tatctgggaa ttgggggaac ggcatccgac
    17821 gctggatctc cggctgttcc tgcatcgcaa tttcgtcatc gggattatca gcctgacact
    17881 cgggttcttc tcgatccaag ggctgttatc tcttctgatc gtccagatcc aacttattct
    17941 cgggtattcc tcgaagctgg ccggtctggc gttgttgccg ttggtgttgc tgagcgcccc
    18001 gatcatcgcc gtcatgcatt atctctgcaa gtatgtcgat gcacgctggc tggtctgcct
    18061 caactgtctc ggttttgcat ggacgtttta ttggatcgga ctgtacgacg atccgcattc
    18121 ctacgaagaa ttgttctggc ccatggtcgt ggagggaatt tttctgggtt ccttcttcac
    18181 gccgatcacc gtgctgacct tgcacggcct ctcgggtccg ttggtgatgc gcgccgcaga
    18241 agttgccaat ttgttgcggg ttgccgccgg agcatttggg atcacgtttc aaggcatcgt
    18301 cctgttccgg cgcattcact tccatcagct gcacttggcc gatcatttcg gaggccggca
    18361 atcgatttca tacgatccga tgggacagtt ggccgcgaaa ttccaggcgg cagggttgtc
    18421 tgtttccgaa gcccaggcca agttggggct ggtgatcaag caggaagcgg caatacttgg
    18481 cctcaacgat gcgtttctcg tggccagttt catctttgtc gggttggggg ggctggtctg
    18541 gttcgcccat ccgacgcatg tgcccatcgc ctccagtcct gaggacgatc tgcgcgtgag
    18601 acgcgctgag gagttgatag aggaggtgcc atgagatcgg gttcaaccgt gggacagcga
    18661 gtgtggaggt gcctggggat cggctgcgtc ctgctcttcg ggagctgcgc gtggattccc
    18721 aagggcgatc ctcctgcgca atatctcgac ccgccggaga tgacggagac actcgctgaa
    18781 atcacgagcc ggctgcagaa ctggccggac gatcattggt gggaacagtt cgggaaccct
    18841 gagttgaacg ggctgatcga aaccgcgctc aaggacaatc ccgggctgaa acatgcgtcc
    18901 gcgcgactgc ggcaggccac ctcgcttgta aaggtggaag gcgcccggtt gttgccgttc
    18961 ctggaagctg atgcctcctt gacctatgag cgtatctccc aacatggcgt gttcgccgcg
    19021 ctgaatcccg aagtggcggg catcaagatc atgtacggga tcatcaaccc gctcagcttc
    19081 cggtatgaat tcgacttctg ggggaagaac cgggcgatgc tcgagggagc gctgggccac
    19141 gcggctgccg aagaggcgga aaccgccgaa gtgcgtctgc gattgaccac cggtattgcc
    19201 cgggcctatt tccgggggca ggccctgcaa cagcaactga cgatcgtgaa gacgattgtc
    19261 ggcatccgcc gcgatctcaa aaatcttgca gagacccggt ttcgtctggg cctcgacaac
    19321 gatcagccgt tcaagatcgc cgtcgccgac tacgaggcgg cattcaagcg gcaagcggcc
    19381 atccgagatc aattggatgt gcagcggcat ttgctcgcgc gcctagccgg gaaggggccg
    19441 gacgaggcag cccatctctt tgccaagcct atggccaaca ttcccaaaca gattcctgcg
    19501 ccggatcatc tgtcgatcgg cctgctggtc catcgccctg atctggcggc agccttgtac
    19561 cgcgcgcatg ccgcgtcacg gttggtcagg gtggcgacga cgcagttcta tcccaccatc
    19621 gatctgacgg gctttgtggg attcaatgcc ctgacgttgg ccaagggaac cgacaagctg
    19681 gcgaattttc tctttagcgg tcagagcttc acctatggcc tggcccccgg attgcggatg
    19741 ccgtggtttg aaggcggccg gttgcggggc gagttgggcg cacagcgcgc ggaatatgac
    19801 gcggcagtgg aactctataa cgacacgctg ctcgatgcga tgcgggaagt agccgacagc
    19861 ctcagtgcct ggcacaccac caatgagatc atggcgtcgc acaaacggct ggtggcgtcg
    19921 ctgggcgaag actggcggtt ggcaaaagtc cgcctcgtca acggcctgga cgatgatcgc
    19981 gaagtgctgc gccaccggta tccggtgctc gaacaggaat atgccctgcg agcgttggaa
    20041 agcgatcaat tagtggccgc cgtcgacctg atcgaatccc tgggcggcgg gtatcacaat
    20101 ccggacatcg aaaagcgacc gaaacacaac ccgagttaaa tgtatgacca ccacaacggc
    20161 agatatgtct caacctccgc aatccccagg agtaccgcca ccggcaggct cctatcgcat
    20221 tcatccgaag gccatacgag cccgccggaa ccggcgccta ttggtcgtcg ctctgctggt
    20281 cctgatcgcc accgtcggct acctcatgta ttggtacacc cacgatcggt tttggatccg
    20341 gaccgacaac gcctatgtta ccggtaacct ggtgccggtg gcggcacagg cgtccggtat
    20401 catcacgcag gtcttggcgg aagaaacaca gttcgtgaac cgcggtgact tgctggtgcg
    20461 actggatgaa catcaagcct atgccgcttt gggaagggcg cgtggacgat tgggggaaga
    20521 ggtccgccgg atcgcggcgc tattcatcaa tcgcaaacaa ctggcggaga aattacggtc
    20581 gcgcatggct cgtttagaac tggccgaaca cgacatggac cgctatcaac gggcatcccc
    20641 gagcggcgcc atctccaagc agatcttgca gaatacggcg gacaagattg cgagcctgga
    20701 agcggaggta cgggaaacac aggcggaact cgactcgctc gatgcgcaga tcggcggcac
    20761 gacggtgatg gcgcatccgt ccgtcgacct ggccaaacac cagttgattg aagcgcatct
    20821 ggaatatgca cgccagcaga tacgcgcccc gatttcaggc tatgtcgcca agcgaaaagc
    20881 gcaggtagga gatcgtgttc agcccggcgc ctcgctgatg accatcgttc cgctggatca
    20941 tctgtgggtc gaagccaatc tgcgggaaac ggaattgcag cacgtgcggc cggggcaacc
    21001 ggcgctggtg agtgtcagtc tgtatggatc gaaacaaacg ttccacggca ccgttgaagg
    21061 tctcgtgccg ggcagcggca gcgcgttcgc cttgcttccc ccggataact ccacgggaaa
    21121 ctttattcac atcgtcgaac gggtgccggt gcgtattgcc ctcccggcgg atgaactccg
    21181 tgaacatcca atcaggccgg ggctgtcgac catgacgagc attaacatta ccgagtcggg
    21241 gcaatcggtg tggacgtctc tcgccacgcc atccacggcc gagtatgaga cggacgtgta
    21301 tgccgatgag cttcccacag cggagtctat ggcgaaggaa gtgatggcga cgaatttggt
    21361 ggtcagcgag aacggagacg gcattgattc actgctcgaa gacgaggggg ccatcgagcg
    21421 ggtgaacccc agaagagacg tggacaggtt gccgaacgag gggaaggcgg ctcctaaact
    21481 tgatcggctt cgagaacggg atgatcggcg tccgagttca ttcgtgccgc gacgcagtcc
    21541 cgatctggga gccaccacct ttcctctcac gccatcgatt ggacccgatt cgaggtcgct
    21601 gggccccgaa gcggggcgca atccatctcg actgaaaccc gggttcggtc tggatgacga
    21661 acggcgcgcg tttggttccg gcaggcgcta gactccctgc catgacgtcg ggccattccg
    21721 gttaggtgat ggaaaagcag caggggtagc acagattatt tttcgatgaa gattgcggcc
    21781 ctggtctgga atgcgcgggc tgcgcatcct atgatgcacc acgcgctccg agcaacaccg
    21841 atagtcaacg ctcgcctggc ttgctgatcg ttccttgcct ctcctgccgg cgtcccgctc
    21901 caaggcgcgc tctcagcggt cgcagacagc ccctctaccg ggccggagac acacgccgtg
    21961 ccgaacgtga cgcttaatta tcgcacgctc ttgtcggtca ccaatgtgct gaattctcag
    22021 cgaaaccggc aaagcctgtt ccgtgccatc accgatcagt tgaccaaagt agtgcggtgg
    22081 gaacgggcag gaattacagt gtacgacctg cagacagacg cctttcgttt ttatgcggtg
    22141 gagacgaacc ttcccaaagt cgtgctgcga agcgatgcga tgattccgcg cgcgcaaagc
    22201 gctgtgggat gggtctatga ccatcaacgc gtgcatgtgc ggcctcacct tcgtgaagag
    22261 cggctgttca tcgaggatga aagttatgcg caggaagggc tgggtcgcat gatcaacctg
    22321 ccgatggttg tgcaggaggc ctgtcttggg acgttgaata tcgggagcat cgaagccggg
    22381 taccccgatc ctgacgatgt ggatttcctt cagcaggtcg cgacccagat cgggtttgcc
    22441 attgctcacg tcaacgccta tgaggaaatc aatcgtctgc gggaacaact cgcccgcgag
    22501 aatgtgtatc tcaccgaaga gctcaaagcg actcaggact acggtatcgt cgcgggacgg
    22561 agccgggcat tcgaggcggt gctgacgctg gcgcggcagg ccgccccgac gaccgcgacg
    22621 gtcatgatta ccggggaaac cgggacgggt aaggaggtgc tcgcgcgagc catccacgag
    22681 agaagtcttc ggcgtgaacg ggcattcgtt cggctgaatt gcgccgccct tccgtccggg
    22741 ttgattgaaa gcgaactctt cggccatgaa cgcggcgcgt ttaccggcgc ggatcatcag
    22801 cgggttggac ggtttgaact ggcggatggc ggcaccttat tcctcgatga gatcggcgaa
    22861 atgcctctcg aggcgcaggc gaagctgttg cgtgtcttgc aggacgggat ggtcgatcga
    22921 gtcggcagtg cgaaacccat tccggtcgat gtccgggtga tcgcggcgac caatgccaat
    22981 ctggaacgcg cgattcagca ggggcgattc cgtagtgatc tgtattatcg cttgaatgtg
    23041 tttcccatcc atatgccgcc gctcagagag cggccggaag acattcccat tctcgcccgc
    23101 cactttttgc ggtttcacgc ccgtcggctg aagcgattgt gtgaagattt tgatgcgtcc
    23161 tcgatggagc gcctcgtgca atacgcgtgg cccggcaatg tgcgagagct tgaaaacctc
    23221 gtggaacgcg gactgatcct ctgtcacgat cgatggttac gtatcgaccc ggccatgatc
    23281 aatctgcccg ccgcttcaga agtgaatccc cgccggacct tggtggacga agagcgccgc
    23341 cacattcttc aatcgctcac gttgctcgat tggcgaatcg aagggcccgg cggcgctgct
    23401 gaacaattgg ggctggcgcc aagtacgcta cgcagtcgac tacaaaagct cggcattcgt
    23461 cgtccctccc gttgctagat accgttctgc ttttcttctc ttacgcgtct ctcctccatg
    23521 ggccatgtca ttctcgcgcc acgattgatc gtggtggcgc tgtggtcgct caccgcggct
    23581 tgtcgtgggt gatgccttcc gtccgccgcg ttcctgaacg tcatcccgtt gaagcgccga
    23641 tatttcaagg acatcactga cgtcccatca acgaggcctg tgtggcacgc gcagtgcaca
    23701 agggctcgtc gtgatttttt ctgccctgat ttttttaatc gaagagcgta gtcccgcgcg
    23761 cggcggcctg cgcatcgttg caccgacgaa tgaccgggca cgggtgcgac gaaatcatca
    23821 ccaatctgga aggggggtat gcatctatcg tcctgtcccg gtcaatcgtt tcatcgggtg
    23881 cggcgccatc acctgtggcg ctgatcctgt gctctgtctt catttgagga ggtgttcatg
    23941 atgcagttat cccgcagaca gttcttgaaa gcctcggcag gaacggtcgc agtggcagct
    24001 gtggccgaca aggccttggc gctgaccgca ctgcaaccgg tcgtcgaggt cgacaatcct
    24061 ttaggcgagt atccggaccg ctcctgggaa cgtgtgtatc acgaccagta ccggtacgac
    24121 tcatccttca cctggtgctg ttccccgaat gatacccatg cctgccgcat ccgggcattc
    24181 gtccggaatg gtgtcgtgat gcgagtggag cagaactatg accatcaaac ctacgaagac
    24241 ctgtatggca accgcggcac gttcgcgcat aacccgcgca tgtgcttgaa gggcttcact
    24301 ttccaccgtc gcgtgtacgg tccctatcgc ttgaaagggc cgttgatgcg gaagggctgg
    24361 aagcagtgga tggacgacgg ctcccccgag ctgacgtcgg atgcgaagcg caagtacaag
    24421 ttcgacagcc ggttcctgga cgatatggtc cgcgtctcct gggatacggc cttcacctat
    24481 gtcgccaagg gtttggtcgt catcggcact cgttatagcg gtgaggccgg agcccgtcgt
    24541 ctccgcgagc agggctatgc gccggaaatg atcgagatga tgaagggggc gggcgtgcgg
    24601 acgttcaagc accgcgccgg aatgccgatt ctcggcatga tggggaaaca cgccaatacc
    24661 cggttcaaca attgtgtctt gccgctcttg gatagctgga ttcggaaggt caacccggat
    24721 caggcgcagg gcggacggta ctggaataat tatacgtggc acggcgacca ggatccgtcg
    24781 caaccctggt ggaacggcac ccaaaactgc gatgtcgatt tgtcggatat gcgcttcacc
    24841 aaactgaata ccagttgggg caaaaacttc gtcgaaaata aaatgcccga agcgcactgg
    24901 aaactggaat ccatcgagcg cggtgcgcgt ctcgtggtga tcactccgga atataacccc
    24961 actgccagcc gagcggatta ctggatccca gttcgtcccg agacggacgg taccttgttt
    25021 ctcggcgcgt ccaaaatcat tctcgacgag aactatcagg atatcgattt catcaagggc
    25081 tttacggata tgccgctgct ggtgcggacg gacaccttgc agtatctgga tcccttcgag
    25141 gtggtgaagg actatcagtt gccggatttc agcaaatcgt actcgggacg attgcaagga
    25201 ttgactcaag atcagatccg ccggctgggc ggcatgatgg tctgggactt ggcaaagggg
    25261 aaagccgtgc cgttacatcg cgaacaggtt ggcgtacatc ttgcgcagag cggcatcgat
    25321 ccggcattga ccggaacgta tcgcgtcaaa ttgctcaatg ggcgcgagat cgatgcgata
    25381 ccgatctatc agatgtatca aattcatctg caggactatg acctcgatac ggtgcatcag
    25441 gtcaatcggg cgccaaaaga tttgatcgtg cgctgggcca gggactgtgg gacggtcaaa
    25501 ccggcagcca tccataacgg tgaaggcgtc tgccattatt tccatatgac ctcgatggga
    25561 cgggcggcag cgttggtcat gatgctgacg ggtaacatcg gaaaattcgg caccggctgc
    25621 cacacctggt ccggtaacta caaggtgggt atctggcagg cggcgccctg gtccggcgca
    25681 ggcgcgagcg tctatttggg ggaagatccg tggaatttga atctcaagga tgacgtacac
    25741 ggcaaggaga tcaagtaccg caaatattat tacggtgagg agcccggtta ttggaatcat
    25801 ggcgacaatg ccctgatcat caacacgccg aagtacggcc gcaaggtgtt caccggcaag
    25861 acccacatgc cgagccccag caaggttcgg tgggtggtga acgtcaacat cctgaacaat
    25921 gcgaaacacc actatgacat ggtgaagaac gtcgacccga acatcgagat gctggtcacg
    25981 caagacatcg agatgacctc ggacgtcaac catgcggatg tggcgtttgc cgtgaattcc
    26041 tggatggagt tcacgtatcc ggagatgacc gcgacggtgt ccaatccctg ggtgcagatc
    26101 tggaaaggcg ggatccgccc cttgtatgac accagaaacg atctcgacag cttttcgggt
    26161 gtggccgcca agctcaagga gatgaccggc gaacagcgga tggcggatac gtacaagttt
    26221 gtctatcaca atcgtgtgga tgtgtacgtg cagcgtatcc tcgatgcctc cagtaccttc
    26281 ttcggctata gcgcggacgt catgctgaag tcggaaaagg gctggatggt catgtgccgg
    26341 acgtatccgc ggcacccgct ctgggaagaa accaacgagt cgaaaccgca ctggacgcga
    26401 tccgggcggc tggaaaccta tcgagtggaa cccgaggcga tcgagtacgg agagaacttc
    26461 atctcccacc gcgaaggccc ggagtgtacc ccgtatctgc cgaatgccat catgacgacc
    26521 aatccctatg tcaggccgga tgactacggg attccggtca cggcgcagca ccatgacgat
    26581 aagacggtac ggaacatcaa gctgccctgg tctgagatca agcagcacgc gaatccgttg
    26641 tgggagaagg gctatcagtt ctactgtgtc acgcccaaga cccgccaccg ggtccatagc
    26701 caatggtcgg tgaacgactg ggtgcagatt tatgagtcga acttcggcga tccgtaccgc
    26761 atggacaaac ggacaccggg tgtcggcgaa caccagttgc acatcaaccc gcaagcggcg
    26821 aaagaccgcg gcatcaacga cggcgactac gtctttgtcg acggtaaccc ggtggaccgg
    26881 ccctatcgcg gctggaagcc ctcggatccg ttctacaagg tgtcccgctt gatgattcgt
    26941 gccaagtaca acccggcgta tccgtaccac gtcacgatgg ccaagcatgc cccgtacgtt
    27001 gccacggcga agtcggtgaa gggacacgag acgcggccgg acggacgcgc cattgcggtg
    27061 gacaccggtt atcagtccaa cttccggtac ggcgcccaac agtcgtttac cagaaactgg
    27121 ctgatgccga tgcaccagac cgactcactc cccggcaagc acacgattgc ctggaagttc
    27181 aagtggggct atgccatcga tcaccatggt atcaacacgg tgccgaagga atgcttgatc
    27241 cgcatcacca aggcggaaga cggcggcatc ggcgcccgtg gcccgtggga accggtgcgg
    27301 acgggcttca cgccgggtca ggaaaacgag ttcatggtca aatggctcaa aggtgagcac
    27361 atcaagatca aagtgtagcg tgacgcgtga atcgtatctc gtgaagcgtc gctcgcgaag
    27421 ggcgcttcac gaacgacgag cgacggattg cgactgaaag gagcaagtca atgccagaag
    27481 tctataactg gcaactggga cggaagatgc tgtatcccta cgaggagcgg catccgaagt
    27541 ggcagtttg
//
LOCUS       DAOQPD010000053        26671 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_837_length_26671_cov_24.284190, whole genome shotgun sequence.
ACCESSION   DAOQPD010000053 DAOQPD010000000
VERSION     DAOQPD010000053.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 26671)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 26671)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26671
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_837_length_26671_cov_24.284190"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(276..2750)
                     /gene="gyrB"
                     /locus_tag="PK063_12515"
     CDS             complement(276..2750)
                     /gene="gyrB"
                     /locus_tag="PK063_12515"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009330 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) complex [Evidence
                     IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HMZ97922.1"
                     /translation="MAKEDQQDNSAKPKSDSYSADQIKVLEGLDAVRKRPAMYIGSTG
                     VDGLHHLVYEVVDNSVDEHMAGFGEAIEVTIHIDGSVTVIDNGRGIPTGMHSTQKKSA
                     AEVALTVLHAGGKFEQGAYTVSGGLHGVGISVVNALSEWLELEIWQDGQVFEQRYERG
                     KPQASLVVTGKTKRRGTKVRFKPDGQIFETLEFSFDVLAQRLRELAFLNKGLAITLKD
                     DRKEKEQVFHYKGGIVSFVDHLNEAKTPLHKPIYVQTERADLILEIALQYNDGYAENL
                     FSFANNINTKEGGTHLVGFKAALTRTINSYANANDLLKKDTESLSGDDVREGLTAVVS
                     VKVRNPQFEGQTKAKLGNSEVKGIVEAAVNDALGTYFEENPPVARKIIGKAIDAARAR
                     EAARKAKDLIRRKSALDGGSLPGKLADCSEKDPALSELFIVEGDSAGGSAKQGRDRKF
                     QAILPLKGKILNVEKARFDKMLSSDEIRTLILALGTGIGRKKEDSDKADKDAFDIART
                     RYHKIVLMTDADVDGSHIRTLLLTFFFRQMPELLERGYIYIAQPPLFKVKKGKTERYL
                     KDEPAMNEYLADLAVEGVEVALENGREFVTGRRLLPILKKLIAFESLLHKVNKKHHEA
                     NMLRAFVDEPALTREVLKDPASLRTVVDHVKATLALVYPKAEPTIEILEDEEHQSSKL
                     VCKVATGGIAYELQVTHELVGSADFRELQKQAPSSIGLGKPPYKIKIKEGEVLKNGSA
                     ELVQAILEEGKQGLNIQRYKGLGEMNPGQLWETTMDPEKRTLLRVNLEDMTGVDEIFT
                     ILMGDEVEPRRNFIQQHALEVRNLDV"
     gene            complement(2904..4034)
                     /gene="dnaN"
                     /locus_tag="PK063_12520"
     CDS             complement(2904..4034)
                     /gene="dnaN"
                     /locus_tag="PK063_12520"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: protein motif:HMM:TIGR00663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HMZ97923.1"
                     /translation="MKVRIGREELLTGLQRVQGVVEKRNTMPILSNILLEAKHDGAEI
                     VATDLEIGMRGLYKATVLEAGGVTISARKLYEIIKELPSGEIELTSGENNWTTIQFGK
                     SQFKVVGLPSSDYPALPSIEREGLTPLAGAGLLELIRKTLFAAGDNDARYILNGLLVS
                     LTTTERKTTLLRLVGTDGHRLAVAEREVGSPNAKPLAQDIKAIIPKKAAQEMRRLLEE
                     GGDEEPLIGFTKNLMIFRKSGLLLTSRLMEGNYPNYQQVVPKESGKRIVVNRGLLESA
                     LRRVSVLSKDKANAVKVSFAAGGMTLFSSNPDYGEATEELVARYEGEALHTGFNARYL
                     LDALSVMDGESVSLQMDTALSPCLIQEAESPGFKCVVMPIKI"
     gene            complement(4058..5401)
                     /gene="dnaA"
                     /locus_tag="PK063_12525"
     CDS             complement(4058..5401)
                     /gene="dnaA"
                     /locus_tag="PK063_12525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HMZ97924.1"
                     /translation="MNQMWNEALEYIQEKVPKQVYETWFTPVVLDRIEETTAYLAVPN
                     KFFGDWLGEHYHDLLAEAVSAAQGGGRMEVSFVVSQKAAPAQAQPDHSAADTAGRGFM
                     ASRSKRGIQLNPKYTFKSFVVGAGNQFAHAACMAVAEQPAKAYNPLFLYGGVGLGKTH
                     LLNAIGNYLAERSDLRIAYLTTEQFTNEVINSIRYDKMIDLRKRYRNVDMLMIDDIQF
                     LAGKERTQEEFFHTFNTLYEAHKQIVLSSDRFPKDMPDIEERLRSRFEWGLIADLQPP
                     DVETRIAILRKKSEDERIALPEDVIHFLANTMKNNIRELEGSLVRVGAYSSLTGQAIT
                     LEMAKNVLRDLIGDKKKIVSIEDIQEAVGSKYHVKIADLKSRRRSKTLVHPRQIAMYL
                     CRELTDASFPEIGRQFGGKDHTTIIHACRQITKAKEADSALHTTLEGLKEQILRA"
     gene            complement(5750..6022)
                     /locus_tag="PK063_12530"
     CDS             complement(5750..6022)
                     /locus_tag="PK063_12530"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97925.1"
                     /translation="MSEHKTLYLLRQPISDPAETLLPSAAETQLADRVSLVLLEAAAS
                     TTPSFPGPIYVLHQDSATPVQGGSRTQISYRELVTLIAEHPSTIVL"
     gene            complement(6037..6387)
                     /locus_tag="PK063_12535"
     CDS             complement(6037..6387)
                     /locus_tag="PK063_12535"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97926.1"
                     /translation="MAATATIALIIRENPLTSAVPVEALRIALGLAAGENPITVILMG
                     PAVHLLAEESDDIVDLEILEKYLPSFEHLQIPFILVHSSGPRPDLQEGFAVTDGTVES
                     ARQAMAAADRVLVF"
     gene            complement(6408..6728)
                     /locus_tag="PK063_12540"
     CDS             complement(6408..6728)
                     /locus_tag="PK063_12540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HMZ97927.1"
                     /translation="MGALKIGLLLSTPPSHPSVQTVASLASEAISQGADVYLYCIDEG
                     VKNLRDPRYTELVGRGMKLFVCAYGCQQHGVSTDQLDPRISLCGLVVLSNIVNGCDRF
                     LAFT"
     gene            complement(6848..8104)
                     /gene="hisS"
                     /locus_tag="PK063_12545"
     CDS             complement(6848..8104)
                     /gene="hisS"
                     /locus_tag="PK063_12545"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HMZ97928.1"
                     /translation="MIKAIKGVKDLLPEESPRWRFIEDTARRWALNYGFQEIRVPIFE
                     TTTLFARSIGATTDIVEKEMYTFADRDGSSLTLRPEGTAGTVRAFIEHNRAADPRPQK
                     YCYAGPMFRHERPQAGRLRQFHQFGVESFGVSDPRADVEVLSLLWRLLSDLTLPGLTL
                     EINNLGYADDRARYKPRLVAFLKGVESRLCGNCQRRIETNPLRVLDCKVPECRAATEE
                     APGLADSLSSPAREHFDHVKAGLTAIGIPFHLNPRLVRGLDYYCLTAFEVTCSHLGAQ
                     NAVGAGGRYDGLVRELGGPTVPAVGFALGLERIALMLPETFVVPAIPRVYVAAFGTQA
                     ADAGFVLLDELRRAGVPADMDFRSASLKAHLRQADRLGALYTILLGDDEVAKGTATVR
                     NMQTKAQEDLPIQDLATAFRNRLLNK"
     gene            8320..9801
                     /locus_tag="PK063_12550"
     CDS             8320..9801
                     /locus_tag="PK063_12550"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: protein motif:HMM:NF014560.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050797 - thymidylate synthase (FAD)
                     activity [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HMZ97929.1"
                     /translation="MTTSARRVIALAPMPPEKSAYALARYSRSPDSIEDSIKWVHGHS
                     SEKFWEQFYFDYGHGSIADLGHVIICFEQISELAAIRLEDEPVWDGQAKSSRYQNFAT
                     SSWFVPATIRGQEIEASYLGILRGLATVYRALHDPLSQFLTEREPRPESMTPAAYQRA
                     ITARAFDVTRYLLPLAAQTNVGQVVSIRTLEKQITRLLSSQIPELRQIGEDLQEACRK
                     PPVNLWGELSGQSAGLGEPMAPTLARYAKPSVYQAEVYSDLARYAKDVLKGTGLDQPS
                     AYGAAEPVDLIEPHDPLDEVVTTLLYRASHAPYRKILALVQDWTEKQKQDTLEVAFQK
                     RGPYDELIKEFRSGYAFIFDVMMDIGGWRDMHRHRRCQQVQQNFTTVHGFETPPILAE
                     AGLEQEYREAMGHVKSDIERLKKSSQEAALYAIPFGFSVRCLFKMDYAEAEYIAKLRS
                     GVKGHWSYRTIAWLMKEKMTARYPILGARMQATPPDVQDALTR"
     gene            9822..10859
                     /locus_tag="PK063_12555"
     CDS             9822..10859
                     /locus_tag="PK063_12555"
                     /inference="COORDINATES: protein motif:HMM:NF024821.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ97930.1"
                     /translation="MNQPLNQIETALLAGDWDRLGYEAGVSVRALEAADEKDPRPYFA
                     LNVTHLIRGEFAEAWRVHAHALQETADIEKVGEWVKAVLKQYPDNPYLNLVQGMFLAQ
                     SGQSEQSVVFYKEAARLAPQSAYPHYFLAQIHERANHLEMAIKEYREAVKLDPAFAAA
                     RTNLGVAYQEQGRLEMAIPQYREVIKLNPNDGVAHANLGCALAEQGKFEPALQAYKEA
                     LRLNPNDAEIHFALGGVYETKGRMDLAVKEYRAATEANPELAPAHTALGWLLMEQSRP
                     SEAMEAFNRAVKANPEEAQALYGIGRIYAAKGKRESAAENFSKAIRFEKDPAKKNAIM
                     NALHASGQTGD"
     gene            complement(10915..11208)
                     /locus_tag="PK063_12560"
     CDS             complement(10915..11208)
                     /locus_tag="PK063_12560"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97931.1"
                     /translation="MKITIQRTGGFAGLQEALASVDTDQMPAAEARRVEELVAKAAFF
                     DLPAIVGGNIKGADVYRLRVTVTDKSRHQSVEFPDHDSPELTSLRALVRSLAP"
     gene            complement(11283..12758)
                     /locus_tag="PK063_12565"
     CDS             complement(11283..12758)
                     /locus_tag="PK063_12565"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97932.1"
                     /translation="MLQEIIESPTATMRPATEHMSSPSASMTVRVGFVPTPTREYRQH
                     RKLLRATTGIASRASVRMMPDRESARVVIPIPIPIPRIIGSRVLMWKQDPSVSEIGIR
                     KAFLPGLLLAGPRDSRISIQGMPLVSPNAMADYIETPGTQEFDAVHTFAVVRQMLTLA
                     QRARGGSVAPWQWNSASNTEGMSVFPRAGVTPNAFYSRNLKALKFFFFTKPGSPPGSP
                     QVFTCRSFDIVAHETGHAVLDGLKPGWLDASNHPQTGGLHESFGDLCAIFLTLSQLDQ
                     VEAIIAQTKANLHDKTFLADMAEEFGLALGRPNGLRNADNDLKLSEVTNEVHDLSQVF
                     TGAIYDVLADIFAFERKPGMRDDARVLLEVAEYLFGLILRAINAAPAANATFADMANQ
                     MLTIAHAEGKPVQYRNFIRNRFTVREIVVSPTPLTADHKAGMKLMPAFTEEIRMSQDR
                     RGCCGTMQLPEYNEGDRVFEDDLEELRNLFSDNGRAKVLHR"
     gene            complement(13203..13472)
                     /locus_tag="PK063_12570"
     CDS             complement(13203..13472)
                     /locus_tag="PK063_12570"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97933.1"
                     /translation="MKGLRFERLGRDRHYNIIFHIGTSYVPVSDETIDELKAQSLLSS
                     ERFLDLLIDKIGYTNYLKEQIRGELQASGDPMTQMTVLQGAIREL"
     gene            complement(13588..13929)
                     /locus_tag="PK063_12575"
     CDS             complement(13588..13929)
                     /locus_tag="PK063_12575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014961968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF190 domain-containing protein"
                     /protein_id="HMZ97934.1"
                     /translation="MAALTLHPMKEIRVIVSGEHRPYVTELLDKVEATGYTIIGNISG
                     KGHHGVREAHFMFSEQESLVMIMAVVPEEKVEPVLAGLRPLFDRHSGVMFVSDVSVSR
                     REYFGKKSGKP"
     gene            complement(13975..17244)
                     /locus_tag="PK063_12580"
     CDS             complement(13975..17244)
                     /locus_tag="PK063_12580"
                     /inference="COORDINATES: protein motif:HMM:NF021578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2309 domain-containing protein"
                     /protein_id="HMZ97935.1"
                     /translation="MIRTDEPADLEPRRMELRGMIRLASEVIAQYWPMRTFVHHNPLH
                     SLEYLPFTETVRRGQQFLGGHGYLPGDLYRRYVKSGRILIRHIDDALAALAKDEEVDL
                     GSCRISQREVMRACLTHGLSRPAEEPLDRLMECEPNEEQVDVLAERLVALSVPTVQDQ
                     MAAAVREDVAALGRDLTLSNWCDRTLGTRIVDQINGELIKWCEAFLDEGHATWSMPGR
                     RQGLYAAWKQVAANEWATCGIADSRRKIAALPEHPEDAVLDCLEALAIPAEFRQDYLG
                     LQLAALPGWAGFIKWRAEENDYAWQQAYPVGLVKFLAVRLWYVRELVEKVCQEELGIE
                     GNYRAVLRFMDQESAGYFMRKEWVAGRLPAAYADRVARLHAQSGSQHNRAALSREWEQ
                     LTHHYQIEFGPRRERAAQRAMARRLLTLAQALDIVPTLLMDAHPTALRQLLDWMAAFP
                     ESAHGPVWLKAFEAGYQDHLFGLLRRAPTRPQPAAPDGQPPVRPQSQSVFCIDVRSEP
                     FRRHLESTGANETYGFAGFFAALIRYRAWGKEHDTEQFPVIMRAKNEVREIPRSYLDH
                     YVSKHQSRAKLVHAGHTLLHDLKENVVTPYVMVESLGWFYVLPMMGKTFLPALYKRLT
                     NWIRRLFVPPIATILTVDKLAPAETEEMVVSEQRALIWKALRDRLGLHGSRVEAEFVE
                     ALRRRALDEDAPVEPFLSEAARAVDLSNEQLTTFLDELRRHYRINRRAASRQKERITR
                     TGFTLDEQVLTLETALRMMGLVRNFARLVLFCAHGSTTENNPFESALDCGACGGNEGK
                     PNARVLAAMANRAPVRERLAKRGIIIPADTHFLAGQVDTTTDEVQLFDLEDAPPTHRK
                     DVARLYDDLREAAQLTSQERCARFPDVGAVLPLDKAAGHVAARSADWSQVRPEWGLSG
                     NTAFIIGRRELTKGLNLSGRIFLQSYDYREDPTDRWLEVLLTAPQVVAQWINMEHYFS
                     AVDNDVYGSGSKIYHNVVGRIGIMSGPWSDLRLGLAWQTVMNDELPYHEPMRLMTLVE
                     ASRARIEKLIARHEILQHFYHNEWVHLAALDPEDGTWYRYMPSGVWRRVQHPSETTQV
                     G"
     gene            complement(17241..18533)
                     /locus_tag="PK063_12585"
     CDS             complement(17241..18533)
                     /locus_tag="PK063_12585"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97936.1"
                     /translation="MTPWLLLAVPLLGASLALLMRAALQRMKTVALTTTGLTLLAVIG
                     TSLAQNEATAAMSLLCLLPATAFLTLLGQPLHRDNSSAWVMTLILLGVALGILTSHAP
                     THELLLILLLGLVCGLLYRHQPGTAPAAWRGMASFGLGILTALLALALPAPAATIASL
                     VTCATLLPLLPLHSGFVAALSGLPGNLPALLAFILPTVGFHSLYLLLPSLSGTVLQTV
                     ALLALAGAVYGSLRALIQSHPLPRLGYASSAFFCMLWWYVADTGTAPVQALVYLSAVG
                     LTTSGLLLAWYAIRARYGDVDFRALGGLAYPMPRFSTLLALLGLAALGMPPFGVFSGF
                     LGMLLTPAFAPSGPFAIIMLVWLTASWYYTDLIQQVVFGRPRLDIRHEDLRQTEWISL
                     MLVLLLLLILGMAPSRMFESHTTAPSSTVAIKGETWTR"
     gene            complement(18607..20301)
                     /locus_tag="PK063_12590"
     CDS             complement(18607..20301)
                     /locus_tag="PK063_12590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proton-conducting transporter membrane subunit"
                     /protein_id="HMZ97937.1"
                     /translation="MSFLALVPLLPLLTAFIVMTGDRADQEQNARSGLFPIAASFLGS
                     LIILIVVTSDGPIMFQLYDPAAIANLAFPIGVYIDRLSAVMMVLITGVTTLIYRYSMG
                     YMYQDRGYRRYLGMLGITTSVLLCMVSSANLVMLFIFWQILSWLLFLLAHNHGHAATL
                     SGASNTFTTLRLSDAAFLAGIVLAYSLYGTFEFQTLFTRAAETPVTLSIWPELGWTMD
                     GVTAVTLLIFGGAMGKSAQFPIHTWLPRSLYAPTPIHALLHAGIINAGGFLLNRLAPL
                     YGLSPTTLHVVFVIGMLTAILGATMMLTQNDIKKTLGFSTIGQMGYMIMECGLGAFSL
                     AVFHLIAHGLFKGTVFLNCGNVIHKARQEPSFPPIDRETEESEFSNLTWSTGFFTTLL
                     LPLVILLVTHGVLRIPLLESQGTVIFLFFIWVTSSQAILSLTRIRAVASWKVSAAMLV
                     TLVIVVFTYLFAVESFTHFLYPNPEEVAFYFKAAALPGRLFDSLVMGTTLLTILSWVY
                     LYAHAHGRTITIPGWIEAFLVRLYVLFMNRLYLDQLYLNIGRVVTQVAHRLEKRLS"
     gene            20692..21066
                     /locus_tag="PK063_12595"
     CDS             20692..21066
                     /locus_tag="PK063_12595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014450001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2294 domain-containing protein"
                     /protein_id="HMZ97938.1"
                     /translation="MTVPVPSKGEKEAAVRTAIIKFEQEFLGRGPDEVRVFIVRDMLV
                     VRLKGVLTPAERQLAKTAEGVDMVKRLRQNLIAQGRERLCEQVADLIGAKITALFTDI
                     DTVVGERIFVFTLESDLEANFR"
     gene            21090..22565
                     /locus_tag="PK063_12600"
     CDS             21090..22565
                     /locus_tag="PK063_12600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiU family protein"
                     /protein_id="HMZ97939.1"
                     /translation="MTQHSLESLTFENSYARLPEVFYAKVNPTPFRAAPFLISANPAA
                     MELIDLDPQEALRPEFAGVFGGSLLVPGMEPLAMLYSGHQFGVYVPQLGDGRAILLGE
                     IVNGRGERWDLHLKGAGMTPFSRDGDGRSVLRSAIREYLCCEAMHGLGIPTTRALCLV
                     GSDDKVYREQVETGATIVRMAPSHVRFGTFEIFYYRKQHEHLQRLADYVIEMHFPDLA
                     QAADKYVRFFAAVVERTAKLIAQWQAVGWSHGVLNTDNMSILGLTLDYGPYGFMDDYD
                     PGFICNHSDYNGRYAFNQQPYIGLWNLSCLAQTLLPFAPKEDLKAALDGYQATVDRYY
                     RDHMRQKLGLREDRGEDEALLQELKSLMVGSRVDYTIFWRELGTFSSDPAAKNERLRE
                     HFLNPDRFDVWAAQYRERLHSEQSRDEERRAGMDRINPKYVLRNYLAQTAIEKAQQKD
                     YSEIDRLLNLLQDPYRDHPGMESYAAAPPNWGKHLSVSCSS"
     gene            22612..23325
                     /locus_tag="PK063_12605"
     CDS             22612..23325
                     /locus_tag="PK063_12605"
                     /inference="COORDINATES: protein motif:HMM:NF014305.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97940.1"
                     /translation="MRFEKLGGLTVRLTGGTDGKGGGNGPWVMLLHGFGALGDDLVPL
                     SEYLDAPAGTRFLFPEAPIPIPMGFGDSRAWWMIDMARIQADRAAGKIRDMSGEIPRG
                     LPEARERVKALLEDVHKKLGADPARTLLGGFSQGAMLSCDALLHSTLPYAGLIQLSST
                     LVARQEWAPLLTKRKGLPLYQSHGTQDPILPFTMAERLRDEFHLAGLVVDWQPFRGGH
                     EIPEPILRRLGSFILKTLV"
     gene            23427..24137
                     /locus_tag="PK063_12610"
     CDS             23427..24137
                     /locus_tag="PK063_12610"
                     /inference="COORDINATES: protein motif:HMM:NF014414.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HMZ97941.1"
                     /translation="MMMAHDRSRTEYLSTQSAYDEWAEDYDDGDPTVLLDQPFLLSML
                     QPFAGCRILDLGCGTGRYLRLASHEAALVGLDLSRGMLERARRQTPPATGATWVQGSV
                     ERIPFTSESFDRIVSGLVLDHVHDLAEFFRGIGTMLRPGGRAIVTAVHPEMQRKTGPT
                     VRFTAAGREYRTEGTIHEKAAIITALQEAGLLIEQLQEPPVTERLIARREAWKDRLGC
                     PALLLLALTRAADSRHDH"
     gene            24127..24882
                     /locus_tag="PK063_12615"
     CDS             24127..24882
                     /locus_tag="PK063_12615"
                     /inference="COORDINATES: protein motif:HMM:NF024109.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HMZ97942.1"
                     /translation="MTIDATMFELQGTDHKRLRGNRILGKDRQILFITGFLSKRWGNK
                     SKALAQWCQDRGWGFCCFDFRGWGDSEGQWGDYRLLHWLEDAEAVTNLLADGPPVTIV
                     GNSLGGWLAWLVAQEQPAVEELILIAPAFNMMDLRAAQISAERREQWQSAGSMPWDDE
                     PLHREAPIPWHWVEDSQTLWRRRLTMPRRVKTTILHGLQDTVIKPEGSWAFVQHVLSQ
                     DPEFPIELLLKTGDHRLSSPEHLDTFRRLVMKE"
     gene            24885..25052
                     /locus_tag="PK063_12620"
     CDS             24885..25052
                     /locus_tag="PK063_12620"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97943.1"
                     /translation="MLVLIHKECGGPALEESPVGEVCAVPVDRFPFSCFSCLEEIIDE
                     SELRLIEDLGI"
     gene            25077..25883
                     /locus_tag="PK063_12625"
     CDS             25077..25883
                     /locus_tag="PK063_12625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2470 domain-containing protein"
                     /protein_id="HMZ97944.1"
                     /translation="MSSLGAHNSGPDSEGPDVPEPSHAEKARTLVHLQQTGGLSTLSR
                     KQPGWPFGSVMPYGLDDQGQPSFLISTMAMHTQNLLGDPRASLLVTPPESQRDPLGAA
                     RVTLMGSVTKVPKDEAAPVRERYLARHANAAYWVDFDDFAFFRMALADIYFVGGFGSM
                     GWVAPAEYLAAAVDPLAETAADLIREMNTTQQETLLLLARECGNLDAQQASITTMDRL
                     GFHLRVKTPERMQGGRFAFTNPVRTAQEARAGVADLAAKAKAGGQVLHSL"
     gene            complement(25929..>26671)
                     /locus_tag="PK063_12630"
     CDS             complement(25929..>26671)
                     /locus_tag="PK063_12630"
                     /inference="COORDINATES: protein motif:HMM:NF016269.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lipid-binding SYLF domain-containing protein"
                     /protein_id="HMZ97945.1"
                     /translation="PREGAPGMIPDARIQRRSCRIILALLLPFLAWTGVASALADDRE
                     QRDLVEQSRMTLSNFLADSNMTWFRDHVPEAKGLFIVPQYMKGALIYGAAGGSGVFVA
                     KDDKTGEWSEPAFFTMGAASFGFQFGAQMSEVVLLVLTQRGVDSLLLGNFKLGADGSV
                     AVGPVGAGVSGATTPNLSADLLSFVRAKGLFAGVSLEGAVLISRDEWSRAYYGKPVTP
                     TDIIIRHEVKNPHSETLRAEIVRATGGK"
BASE COUNT         5504 a         7768 c         7961 g         5438 t
ORIGIN      
        1 acgcgcgacc gacgatcacg ctcatcgcgt agtcaaggta cgacgagcgc atctcgtctt
       61 cgatcgcaat ttggcctaat cgttcatctg gcggcatcta ccctccacgg atgctgacaa
      121 tgtctcttgg cttcgttctc ggctcgagaa ggtcctcaac gtacccctga gtctacgcgt
      181 ccggtcctct cttgcctgcg gccttgccga agcccatttt tgagcatcct tcgaattcag
      241 aaaaccaaag tggttgtgtc tacgatcacg accgactata cgtccaaatt ccggacttcc
      301 agcgcatgtt gctggataaa gttacgccgg ggctccactt catcgcccat gagaatcgta
      361 aaaatttcat cgacgcccgt catgtcttcg aggttgacgc gcaacagcgt gcgcttctcg
      421 ggatccatcg tggtttccca gagctggccc ggattcattt cgccgagacc tttataccgt
      481 tgaatgttca agccctgttt gccttcctcc aggatggcct gtaccagctc ggccgagccg
      541 ttcttgagaa cctcaccttc cttgatcttg atcttgtacg gaggtttccc caacccgatc
      601 gaggagggag cctgtttctg caattcacgg aagtcagccg atccgaccag ctcgtgcgtc
      661 acctgcaact cataggcgat tccgccagtg gcgaccttac agaccagttt gctcgattga
      721 tgctcttcat cttccaggat ctcgatcgtc ggttcggcct tcgggtagac cagtgccagt
      781 gtggccttca cgtgatcaac gaccgtgcgc agcgacgccg gatccttcaa gacttctcgc
      841 gtcaacgccg gttcatcgac gaacgcccgt agcatgttgg cttcatgatg cttcttgttg
      901 accttatgca gaaggctttc gaaggcaatc agcttcttga gaatcggcag caaccgccgg
      961 cccgtgacga actcgcggcc gttctcgagc gcgacttcca ccccctccac ggcaaggtcg
     1021 gcgagatact cgttcatcgc cggctcgtcc ttcaggtacc gttccgtctt gcctttcttc
     1081 actttaaaga ggggaggctg cgcgatgtaa atgtagcccc gctccaacag ctcaggcatc
     1141 tgccggaaga agaaggtgag caacagcgtg cggatgtggc tgccgtccac gtcggcgtcg
     1201 gtcatcagca caatcttgtg gtaccgcgtc ctggcgatgt cgaacgcgtc cttgtccgcc
     1261 ttgtcggaat cttctttctt tcggccgatg cccgttccca gcgccagaat cagcgtgcgg
     1321 atttcgtcgc tgctcagcat cttgtcgaac cgcgcttttt ccacattgag gatcttgccc
     1381 ttgagcggga ggatggcctg gaacttccgg tcgcggccct gtttggccga tccaccggcg
     1441 gaatctccct cgacaatgaa cagttcgctc aaggccggat ctttttcgga acagtcggcc
     1501 agcttgccgg gcaaggatcc gccgtcgaga gcgctttttc gccggatgag atctttcgct
     1561 ttccgcgcgg cctcgcgggc gcgcgccgca tcgatggcct tgccgatgat tttgcgagcg
     1621 accgggggat tctcttcgaa gtaggtgccg agtgcgtcgt tgactgccgc ctcgacaata
     1681 cccttcactt cgctattgcc gagtttcgcc ttggtctgtc cctcgaattg cgggttccgc
     1741 actttgacgc tcaccaccgc cgtcaaccct tcccgcacat cgtcgccact caacgattcc
     1801 gtatccttct tcaggaggtc gttggcgttg gcgtaactat tgatcgtgcg ggtcaacgcg
     1861 gctttgaacc ccaccagatg cgtgccgcct tccttcgtgt tgatattgtt cgcgaaggaa
     1921 aacaggtttt cggcgtagcc gtcgttgtat tgcagcgcaa tttccagaat gaggtccgcc
     1981 cgttccgtct gcacataaat cggcttatgg aggggcgttt tcgcttcgtt gaggtgatcg
     2041 acgaaagaga cgataccgcc cttgtaatgg aaaacctgtt ccttttcctt gcgatcgtcc
     2101 ttgagggtga tagccaaccc tttgttgaga aaggcgagtt cccgaagtcg ctgcgccaag
     2161 acatcgaagc tgaattccag cgtttcgaat atctggccat cgggcttgaa gcgcaccttg
     2221 gtgccacggc gtttggtctt gccggtgacg accagcgacg cctggggttt cccgcgttca
     2281 taacgctgtt cgaatacctg gccgtcctgc cagatttcca actccagcca ttcggacagg
     2341 gcgttgacga cggagatgcc gacaccgtgc aacccgccgg acaccgtgta ggcgccctgc
     2401 tcgaatttgc cgccggcgtg caggacggtg agcgccactt ctgcagcgga tttcttttgc
     2461 gtggagtgca tcccggtggg aataccgcgt ccgttatcga tgaccgtcac gctgccgtcg
     2521 atatggatcg tgacttcaat ggcttccccg aagccggcca tgtgttcgtc gacgctgttg
     2581 tcgaccactt cgtagacgag gtgatgcaac ccgtccacgc ccgtgctgcc gatgtacatg
     2641 gcaggtcgtt tgcgaacggc atcgaggcct tcgagtactt tgatttgatc cgcgctgtaa
     2701 ctgtcggatt tgggcttggc ggaattgtcc tgctggtctt ccttggccat tcagctccta
     2761 gcaggatact gaccacgtcc gccggcggcg ttctcgcatc gcggaggccc tcaacgtacc
     2821 gcaagggtac gcctcggccc tccactcgct acggccttgc cggacgattg tgttgagtat
     2881 cctgaaacag gtcatgtttg atgctagatc ttgatcggca tcacgacgca tttgaatccc
     2941 gggctctcgg cctcctgaat caagcagggg ctcaaggccg tgtccatctg caacgaaacc
     3001 gattctccgt ccatgacgct cagagcgtcc aaaaggtatc gggcattaaa gccggtatga
     3061 agggcttcac cctcgtagcg agccaccaat tcttccgtgg cttcaccata gtccggatta
     3121 ctggagaaga gcgtcatgcc gcccgcggcg aaagacacct taacggcatt ggccttgtcc
     3181 ttcgacaaca ccgacacacg gcgcaaggcg ctctccaaca atcctcgatt gaccacaatg
     3241 cgcttaccgc tctccttcgg gaccacctgc tggtagttgg gataattccc ttccatcagg
     3301 cgggacgtca ggagcaggcc gctcttgcgg aagatcatga ggtttttcgt gaagccgatc
     3361 agcggttctt cgtcgccgcc ctcttcgagc aggcgccgca tttcctgagc cgcctttttg
     3421 gggatgatcg ccttgatgtc ctgcgccaac ggcttcgcat tcggactccc gacctctcgc
     3481 tccgccaccg ccaggcgatg accgtcggtg ccgacgaggc gcaacaacgt cgtcttcctt
     3541 tcggtggtcg tcaaactgac gagcaggccg ttgaggatgt agcgagcgtc gttgtcaccg
     3601 gcggcgaaca gggtcttgcg aatcaactcc agcaggcctg cccctgccag cggcgtcagt
     3661 ccctcccgtt cgatcgaggg caacgcggga taatcgctgc tcgggaggcc gacgactttg
     3721 aattggctct tgccgaattg gatggtggtc caattgttct cgcccgaggt gagctcgatc
     3781 tcgccgctcg gcagttcctt gatgatctcg tacagcttgc gcgccgaaat ggtgacgccg
     3841 ccggcttcca acaccgtggc cttatacaac ccccgcatcc cgatttcgag atccgtcgcg
     3901 acgatttccg ccccgtcgtg tttggcctcc agcaggatat ttgagaggat cggcatggtg
     3961 ttgcgtttct ccacgacacc ctgcacgcgc tgcaggcccg tcaacaattc ctctcgtccg
     4021 atgcgtacct tcatggtcgg tctccctcag agggccttca cgccctcaag atctgttctt
     4081 tcaagccttc gagcgtcgtg tgcagcgcgc tgtcggcctc tttggctttc gtgatctgcc
     4141 ggcaggcgtg aatgatcgtg gtgtgatctt tccctccgaa ctggcggccg atctcaggaa
     4201 acgaggcgtc ggtcagttcc cgacagagat acatggcgat ctggcgggga tgcaccagcg
     4261 ttttgctccg ccggcgcgat ttcagatcgg caatcttcac atggtatttc gatcccaccg
     4321 cttcctggat gtcttcgatg gagacaatct tctttttgtc accgatgaga tcgcgcaaga
     4381 cgttcttcgc catctccagc gtgatggcct ggcccgtgag cgaggaatag gcgccgaccc
     4441 gcacgagcga cccctccaac tcacggatgt tgttcttcat cgtgttcgcc agaaaatgga
     4501 tcacgtcttc gggaagggca atccgttcat cctcggactt cttcctcaag atggcgatcc
     4561 gggtttcgac gtccggcggc tgcagatcgg cgatgagccc ccattcaaac cgcgaccgaa
     4621 gccgctcttc aatatcgggc atgtctttcg gaaagcggtc actcgagagg acgatttgtt
     4681 tatgcgcttc atacagcgta ttgaaggtgt ggaagaattc ttcctgcgtc cgttccttgc
     4741 ccgccaaaaa ctgaatgtcg tcgatcatca acatatcgac attgcgatag cgcttccgga
     4801 ggtcgatcat cttatcgtag cgaatcgagt tgatgacctc gttcgtaaac tgttccgtcg
     4861 tcaaataggc gatccgcaga tcgctgcgct cagccagata gtttccaatc gcattcaaca
     4921 ggtgagtctt ccccaatccc accccgccat acagaaataa cgggttgtac gctttcgccg
     4981 gttgctcggc cacggccatg caggctgcgt gggcaaactg gtttccggcg ccgaccacga
     5041 aacttttgaa ggtatatttg ggattgagct gaatgccgcg cttggagcgc gaggccatga
     5101 atcctcgtcc cgccgtatcc gcggccgagt gatctggctg cgcctgagcg ggtgccgcct
     5161 tctgactgac cacaaacgaa acttccatac gcccgccacc ctgggcagcc gataccgctt
     5221 ccgcgagcag atcgtgataa tgctccccga gccaatcccc gaaaaacttg ttcggaacgg
     5281 cgagataagc ggtcgtctct tcaatccggt ccagcaccac cggggtgaac caagtttcat
     5341 agacctgttt cggcaccttc tcctgaatgt actccaacgc ctcattccac atctgattca
     5401 tctttttatt tcaatcactt acaaatgttc acaggcttat acacaggtgt ggacaaatac
     5461 ataggaacac gcgattggct tgatgcggcg ctgggaatct ttccagggtt cctgtggaca
     5521 tcgaatcatt ccgacaatca tcgcgatccc tcgtgcacag gcctcctcac gttatccctg
     5581 aaggccccct gccttataca ccatctcatc aacatgggcc aggatcttcc atcgccaatg
     5641 cccgcgcagt ccttcacgct catccacaga acccacacgt cctactccta ctccgacggc
     5701 tccggatctt ctctttataa agaacatata taagagaaga gcatccagat cacagcacaa
     5761 tggtcgaagg atgctcagca atcaaggtga ccagctctcg ataggaaatc tgtgttcggg
     5821 aaccaccttg aaccggtgta gcggagtcct gatggagaac gtagatcggg ccgggaaagg
     5881 aaggggtcgt cgatgcggca gcttccagaa gtacgagaga gacccggtca gccagttgag
     5941 tctcggccgc agacggtaac agcgtctcgg ccggatctga aatcggctgg cgaagaagat
     6001 acagggtctt atgctcagac atacaactca gccttcctaa aacaccaaga cccggtcagc
     6061 agcagccatg gcctgccggg cggattctac tgtcccgtca gtgacggcaa atccttcctg
     6121 aaggtcgggc cgcggcccgg aggaatggac gagaataaag ggaatctgga gatgctcgaa
     6181 ggaggggaga tatttttcga ggatctccag atcgacaatg tcgtctgatt cttcagccag
     6241 gagatgaacc gcaggtccca tgagaatgac ggtgattgga ttttcacccg ccgccaaccc
     6301 taaggcaatg cgaagtgctt cgaccggaac agcggaggtc aaaggatttt cccgaataat
     6361 caaagcgatg gtagcggtcg cggccacaat tcaatccctc aggcacatta ggtgaaggcc
     6421 agaaatcggt cgcagccatt cacaatattc gaaagcacga ctaacccaca gagtgagatg
     6481 cggggatcga gttgatccgt cgagactcca tgctgctgac acccgtaggc acagacgaac
     6541 aacttcattc cgcgcccgac gagttctgta tatcgggggt cccgaagatt cttcacccct
     6601 tcatcgatgc aatacagata cacgtcggcc ccctggctga tcgcttcgga cgctagtgag
     6661 gcgaccgtct gtacactggg gtgtgacggg ggtgtggata acaggagacc gatcttcagc
     6721 gcgcccataa aaaatgtgcc tgtggaaaaa ctttaggagt tcttaataat caattactta
     6781 tatgttttat actgcacgcg gagcgtacga attttgggcc ggaaagtcaa ctagaaactg
     6841 agcgggatta cttgttgaga agtcggtttc gaaatgccgt tgcgaggtcc tggataggaa
     6901 gatcttcctg tgctttcgtc tgcatattgc ggacggtcgc ggttcctttt gcgacttcat
     6961 catcacccag gagaatggta tagagcgctc caaggcgatc ggcctgcctg agatgagcct
     7021 tgagggatgc ggagcgaaaa tccatatccg ccgggacacc ggcccgacga agttcatcga
     7081 gcaggacaaa cccggcatct gcggcctgtg taccgaaggc cgcgacatag actctcggga
     7141 tggcgggtac gacaaaggtc tcgggcagca tcaacgcgat ccgttcaaga ccgagggcga
     7201 accccacggc gggaacagtt ggccctccca gttctctgac caatccatca taccgtccgc
     7261 cggcacccac tgcgttttgc gcccctaagt gcgagcaggt cacctcgaaa gccgtgaggc
     7321 aatagtaatc gagaccgcgg accaggcgag gattcaagtg gaagggaata ccgatggcgg
     7381 tcaagccggc cttcacatga tcaaaatgct cacgggccgg cgatgacaga gaatcagcca
     7441 ggccaggtgc ctcttccgtg gcggcacggc attccggcac cttgcagtct aagacccgca
     7501 agggattcgt ttcgatgcga cgctgacaat tcccgcagag acggctttca acacccttca
     7561 aaaacgccac gagccgcggt ttataccggg cccgatcgtc ggcgtatccg aggttgttga
     7621 tttccaaggt caaccccggc agggtgagat cagaaagcag tctccacagg agcgacagca
     7681 cttcgacatc agcccgtgga tccgacacgc cgaaggattc caccccgaac tgatgaaact
     7741 gccggagccg cccggcctgt ggccgttcgt gccggaacat gggaccggca tagcagtatt
     7801 tctgcggcct ggggtcagca gctcggttgt gttcgatgaa tgcccgaacc gttccggccg
     7861 tcccttccgg tcgcaaggtc agggaggagc cgtcgcgatc cgcgaaggta tacatctcct
     7921 tctcaacgat gtccgtcgtc gcgcctatac tgcgggcaaa taatgtcgtg gtctcaaaga
     7981 tggggacgcg aatttcctga aatccgtaat tgagcgccca gcgccgagcg gtatcttcga
     8041 tgaatcgcca acggggggac tcttccggaa ggagatcttt gacgcctttg atggccttaa
     8101 tcatggctct aatcgtggat tcgcggtcgt tcgagcgggg actataacgg cgggcttgcg
     8161 ggcaagtcaa cgcgatgagc ggttccatct catgagcgac ggcgctgttg cacccttttc
     8221 gctgcgggcg tatagtgccc tccttgtaaa aatggcatgg cgctgctgcc gcctcagtac
     8281 gttcgcttca caagacgccc ggtctcatac ttcaagccta tgacgacttc agcccgccgc
     8341 gtgattgccc tggctccgat gcctccggag aaatccgcct atgccctcgc gcggtatagc
     8401 cggtctccgg actcgattga agacagcatc aagtgggtcc acggccattc atccgagaaa
     8461 ttctgggaac agttttattt cgactatggg catggttcga tcgcggacct cggccacgtc
     8521 attatctgct tcgagcagat ttccgaactc gccgccatcc ggttggagga tgaaccggtg
     8581 tgggatggcc aggccaagtc gagccgctat cagaatttcg ccacctccag ctggtttgtc
     8641 ccggccacca ttcgaggaca ggagattgag gcgagttatc tgggcattct ccgcgggctc
     8701 gcgacggtct atcgcgcctt gcatgacccg ttgagccagt tcctcaccga gcgtgagccg
     8761 cgaccggaga gcatgacgcc tgctgcctac cagcgggcta tcaccgcgcg ggccttcgat
     8821 gtcacacggt atttactccc cttggcggcg cagaccaatg tggggcaggt cgtcagcatc
     8881 aggacgctcg aaaaacagat cacccgcctc ttgtcctcgc agataccgga gttgcgccaa
     8941 atcggagaag atttgcagga agcctgtcgc aagccgccgg tcaatctgtg gggtgagttg
     9001 tcgggtcagt cggccggatt aggtgagccg atggctccga ccttggcgcg gtacgcgaag
     9061 ccgagcgtct accaggccga agtgtacagt gacctggctc gctacgcgaa ggacgtgctg
     9121 aagggcaccg gcttggatca accctccgcc tatggggccg cggaaccagt agatttgatc
     9181 gaacctcacg acccgttgga cgaagtggtg accacgctgc tctatcgcgc ctcccacgct
     9241 ccgtatcgaa agattctcgc cctcgtccaa gactggaccg agaaacaaaa gcaggacacc
     9301 ttggaagtcg cgtttcagaa acgcgggccg tatgatgaat tgatcaagga attccgcagc
     9361 gggtatgcct ttatcttcga cgtcatgatg gatatcggcg gctggcgcga catgcatcgg
     9421 caccgccgct gccaacaggt gcagcagaat ttcacgacgg tgcatgggtt cgaaacaccg
     9481 cccatcctcg cagaagccgg gctcgaacag gaataccgag aggccatggg acatgtgaaa
     9541 tcggacattg agcggctgaa gaaatccagc caggaagccg cgctgtatgc cattccattc
     9601 ggattttccg tgcgctgtct gttcaagatg gactatgccg aggcggaata catcgcgaag
     9661 ttgcgatccg gcgtgaaggg gcactggtcc tatcgcacca tcgcctggct gatgaaagaa
     9721 aaaatgaccg cacggtatcc catcctcggc gcgcgcatgc aggcgacccc gccggatgtg
     9781 caggatgcat tgacgcgctg accggcgcac cgaaccgtct catgaatcag cctctcaacc
     9841 agatcgaaac ggccctcctt gcgggcgact gggaccggtt agggtatgaa gccggggtct
     9901 cggttcgtgc gctcgaagcg gccgacgaaa aagacccccg gccatatttt gcgttgaatg
     9961 tcacacacct gattcgcggt gaatttgccg aggcctggcg ggtgcatgcc catgcattgc
    10021 aggaaacagc ggatattgag aaggtgggcg aatgggtaaa agccgtcctg aagcagtatc
    10081 ccgacaatcc ctacctgaac ctggtacaag gcatgtttct ggcgcagtcc ggccagtcgg
    10141 aacaatcggt ggtgttctat aaagaagcgg cgcgccttgc gccacagtcc gcctatcccc
    10201 attattttct ggctcagatc catgagcggg cgaaccatct ggaaatggcc atcaaggagt
    10261 accgcgaggc ggtcaaactg gatccggcat tcgccgcggc ccgcaccaac ctgggcgtcg
    10321 cctaccagga gcagggccgg ctcgaaatgg ccattcctca atatcgcgaa gtgatcaagc
    10381 tcaatccgaa cgacggcgtc gcccatgcga atctcggctg cgccttggcg gagcagggga
    10441 agtttgaacc ggcgctccag gcctacaagg aggcactgcg cctcaatccg aacgacgcgg
    10501 agattcactt cgcattgggc ggagtctacg aaacgaaagg ccgcatggat ctcgcggtca
    10561 aggaataccg cgcggccacg gaagccaatc cggaactcgc gccggctcac accgcgcttg
    10621 gctggttgtt gatggagcaa tcccgaccga gtgaggccat ggaggccttc aatcgcgccg
    10681 tgaaggccaa ccccgaggaa gcgcaagcgc tctacggcat cgggagaatc tacgccgcta
    10741 agggcaaacg ggaaagtgct gccgaaaact tctccaaagc catccgcttc gaaaaagatc
    10801 ccgccaagaa aaatgccatc atgaacgctc tccacgccag cggtcagacc ggggattagt
    10861 gaaatcgaag agcttgtagg aagcccggcc gtcccacaca cgacccacgg tcgactaggg
    10921 agccagggac cggacgagag ctctcaggga ggtcagttca ggggagtcgt gatcaggaaa
    10981 ttcgacgctc tggtgacgcg atttatctgt aacagttact cgcagacggt agacgtctgc
    11041 gcctttgatg ttgccgccga ctatggccgg tagatcaaag aacgcagctt tcgcgaccaa
    11101 ttcttcgacg cgcctcgcct ccgcagccgg catctgatcc gtatcgacag aagccagtgc
    11161 ctcttggagc ccggcgaacc caccggtgcg ttgaatcgtg atcttcatcg cctgtcctca
    11221 gtggagctca atggcggccc gggcaccgta tggcctcccg agccgcctca ttgagactga
    11281 tcttatcgat ggaggacctt cgctcttcca ttgtcgctga aaaggttccg gagttcctcc
    11341 agatcgtctt cgaatacacg gtccccctca ttatattcgg ggagctgcat ggttccgcag
    11401 cagcctcgcc ggtcttggct catccggatt tcttccgtaa acgccggcat gagtttcata
    11461 cccgctttat ggtcggcggt gagcggcgtc ggcgagacga cgatttcccg aaccgtgaag
    11521 cggttgcgaa tgaagtttct gtactggacc ggcttgccct ctgcgtgcgc aatcgtcagc
    11581 atctggttgg ccatatcggc gaaggtggca tttgcggccg gagcggcgtt aatggctcgg
    11641 aggatcaggc caaacagata ctccgcgact tcgagcagga ccctggcgtc gtcccgcatc
    11701 ccgggttttc gctcaaacgc gaagatatct gcgagcacat cgtagatggc tcccgtgaag
    11761 acctgtgaca gatcgtgcac ttcgttggtc acctcgctca gcttcaaatc attgtccgca
    11821 ttgcggagac cgttcgggcg gccgagtgca aggccgaatt cctcggccat gtcggcaagg
    11881 aatgtcttgt catgcaagtt cgctttggtc tgggcgatga tcgcctccac ctggtcgagt
    11941 tgggaaagcg tcagaaagat cgcgcagagg tcgccgaacg attcatgcaa tccaccggtc
    12001 tgcggatgat tgctggcgtc gagccaccct ggcttaaggc catccaggac ggcgtggccg
    12061 gtttcatgcg ccacgatatc gaacgagcgg caggtgaaca cctggggaga ccccgggggg
    12121 ctgcccggct tggtgaagaa gaagaatttc aaggctttga gattgcgact gtagaacgca
    12181 ttgggagtga cgccggcccg cggaaagacg ctcatccctt ccgtgttgga ggcgctgttc
    12241 cattgccacg gtgccacgga tccgccacgt gcccgttgcg cgagagtgag catttgccgg
    12301 acgacagcaa aggtgtggac cgcatcaaac tcctgcgtcc ctggagtctc aatatagtcc
    12361 gccatggcgt tgggggagac gaggggcatg ccttgaatgg aaatgcggct gtctctcggg
    12421 cccgctaata acagaccggg gagaaaggcc ttgcgaatcc cgatttcgct gaccgagggg
    12481 tcctgcttcc acatcagcac tcgagagccg atgatccggg ggatgggaat cgggatcggg
    12541 atgaccaccc gggctgattc ccggtcgggc atcatgcgaa cggaggcacg gctggcgatg
    12601 ccggtggtag cacgcaagag ttttcgatgc tgccgatatt cacgtgtcgg agtcggaacg
    12661 aacccgacgc gaaccgtcat gctggccgaa gggctactca tgtgttcggt ggctggtctc
    12721 atggtcgccg tcggactttc aatgatctcc tgaagcatgg ctcttaccct tgtcctttct
    12781 gagtcgatag cggccgcgct ggattttgga ttggaggcac cgactcgatg tgagggagaa
    12841 tgcttttgcg tgacctggct ggttcgtccg ttggatgaca gagtggacat gcgactcacc
    12901 tccttccccg caaaagaaaa agcaagtgtc gtaccgtctc gattctgtga ccggtcgtct
    12961 ccggcgcttc gaaacgagaa tcgggatttc agctggttgg taatggtggc attgtttgcc
    13021 ggtttctacc taggcgtatc tcaggagata cagccaaggc ttgggcgtat ctatttccgt
    13081 acagggcaag gtgtttcaac ggagcatgta ccgtggacgt gcaggagatg tcctgacacg
    13141 agggtgttca gggaacaagt atatggtcga tggatgaaac tgtggagcga aggagcaggg
    13201 atctacagtt cgcgaatggc gccttgtagg acggtcatct gagtcatggg gtcgccggag
    13261 gcctggagtt ccccccggat ctgttctttg agatagttgg tgtagccgat tttatcgatg
    13321 aggaggtcga gaaaacgttc ggaggacaac agactttgcg ccttcagttc gtcgatggtc
    13381 tcgtcgctca ccggcacata gctggtgccg atgtggaaaa tgatgttgta gtggcgatcg
    13441 cgcccgagtc gttcgaaccg taatcccttc acgtgccgtc cttcctctta caggccaacg
    13501 ggggcacatt gtagacaatc actcatgaga agacaaggtc agtctggggc cctgcggccc
    13561 cgccagccgt ggcttcccgg ctaccggtca gggcttcccg ctcttctttc cgaaatattc
    13621 ccgccggctg acggacacat cagacacgaa catgactcct gagtgccgat cgaacagcgg
    13681 ccgcaatccg gccaagaccg gttccacctt ttcttccggc accaccgcca tgatcatgac
    13741 caggctttcc tgctcactga acatgaagtg cgcctcgcgt acgccatggt gtcccttacc
    13801 ggagatgttc ccgatgatcg tgtacccggt cgcttcgacc ttgtccagca attccgtgac
    13861 gtacggccga tgttccccgg acacaatgac acgaatttct ttcatgggat gcaatgtgag
    13921 tgcggccatg tctcgactcc tttgaaaatg atcgtcggtt gcgacagtga gcggttaccc
    13981 tacctgtgtg gtctcgctcg gatgctgaac ccttcgccat acgcccgacg gcatgtagcg
    14041 gtaccaggtg ccgtcttcag gatccaacgc ggccaggtgg acccactcat tgtgatagaa
    14101 atgctgcagg atctcatgcc gcgcaatgag tttttcgatc ctcgcgcgcg aggcttccac
    14161 gagcgtcatc aggcgcattg gctcatgata aggcagctca tcgttcatga cggtctgcca
    14221 ggccaggccg agacggagat cgctccaggg gcctgacatg attccgatgc ggccgacgac
    14281 gttatgataa atcttgctcc cgctgccata cacgtcgttg tctacggctg agaaataatg
    14341 ttccatgttg atccactgcg ccaccacttg cggggcggtg aggagtactt cgagccagcg
    14401 atcggtcggg tcctcgcgat aatcgtagga ttgcagaaag atgcgcccgg acaggttcag
    14461 ccccttcgtc agttcccgcc ggccaatgat gaaggcggtg ttcccggaca ggccccactc
    14521 ggggcgcacc tgactccagt ccgcgcttcg tgccgccaca tgacctgctg ccttgtccaa
    14581 gggcaggaca gccccgacgt cgggaaatct ggcacagcgc tcctggctgg taagctgggc
    14641 tgcttcccgc agatcgtcat acaggcgggc gacatccttg cggtgggtcg ggggcgcgtc
    14701 ttcgagatcg aacagctgta cctcatcggt cgtggtatcg acctgccccg caaggaaatg
    14761 cgtatccgca ggaataatga tgccgcgttt cgccagccgt tcgcgcaccg gagcgcggtt
    14821 ggccatcgcg gccagcacac gggcattcgg tttgccctcg ttcccgccgc aggcgccgca
    14881 gtccagcgcc gactcgaacg gattgttttc cgtcgtgctg ccgtgggcac agaagagtac
    14941 cagccgggcg aaatttcgta ccaggcccat catgcgcaag gccgtttcga gggtcaggac
    15001 ctgctcgtcg agtgtgaaac cggtgcgggt gatgcgttct ttctggcgcg aggccgcacg
    15061 tcgattaatg cgatagtgcc gccgcagttc atcaaggaag gtggtcagtt gttcgttgga
    15121 cagatcgact gcgcgggcgg cctcactgag gaatggttcc actggcgcat cctcgtccag
    15181 ggcccgacgt cgcaacgcct cgacaaattc cgcctcgact cgcgaaccgt gcaggcccag
    15241 ccggtcacgc agggctttcc agatcagggc gcgttgctcg gagaccacca tttcttccgt
    15301 ttccgccggc gccagcttgt cgacggttaa aatggtggcg atcggcggca cgaacaaccg
    15361 ccggatccag ttggtcaggc gtttgtacag cgccggcagg aaggtcttgc ccatcatggg
    15421 caggacgtaa aaccagccga gcgattcgac catcacatag ggcgtgacga cgttttcctt
    15481 caagtcgtgc aggagcgtgt gaccggcatg gaccagcttc gcccgcgact ggtgtttgga
    15541 cacgtaatgg tccaaatagc tgcgcgggat ttcgcggact tcgttctttg cgcgcatgat
    15601 cacgggaaac tgctccgtat catgctcctt gccccacgcg cgatatcgga tgagggcggc
    15661 gaaaaatcct gcgaaaccgt aggtctcatt ggcgcctgtg gactccagat gacggcggaa
    15721 cggttcggat cgcacatcga tgcaaaagac cgattgggac tgggggcgga ccggcggttg
    15781 accgtcgggg gcagccggtt gcggcctggt tggcgcacgc cggagcaggc cgaacagatg
    15841 atcctgatag cctgcctcaa acgccttcag ccaaaccggg ccatgggccg attccggaaa
    15901 ggcagccatc caatccaaga gctggcgaag cgcggttgga tgggcgtcca tcaagagggt
    15961 cggcacaatg tcgagtgcct gcgcgagcgt gagcagacga cgcgccatag cccgctgcgc
    16021 agcccgttcg cgacgcgggc cgaattcgat ctgataatga tgcgtgagtt gttcccattc
    16081 acgggagaga gccgccctgt tgtgttgact ccccgattgc gcatgcaggc gtgccacccg
    16141 atcggcatag gcggccggca ggcggccggc gacccattcc ttgcgcatga agtatccggc
    16201 cgactcctgg tccataaacc gcagcaccgc gcgatagttt ccctcgatgc ctaattcctc
    16261 ctgacagact ttctcgacga gttcgcgcac ataccagaga cgcacggcga gaaatttcac
    16321 cagaccgaca gggtaggcct gttgccaggc atagtcgttt tcttcggccc gccatttgat
    16381 gaagccggcc caaccgggca gcgcggcgag ctgaaggcca aggtagtcct gccggaattc
    16441 tgccggaatc gccaacgcct cgaggcaatc caagaccgcg tcttccggat gttcgggcag
    16501 cgcggcaatt ttgcgacggc tatcggcaat gccgcaggtc gcccactcat tagcggccac
    16561 ctgtttccac gctgcataca gcccctgacg ccgtcccggc atcgaccagg tggcatggcc
    16621 ttcgtcgagg aaggcttcgc accatttgat caattcgccg ttgatctgat ccacgatccg
    16681 ggtgcccaga gtccggtcgc accagttcga taaggtaagg tcccgtccca gcgcggccac
    16741 atcttcgcgc accgcggcgg ccatctggtc ttgcacggtc ggcacggaca aggcgacgag
    16801 gcgttcggcc aagacgtcca cctgttcctc gttcggttcg cattccatga gccggtcgag
    16861 aggttcctcg gccgggcgag acagtccatg agtcaggcag gcacgcatga cttcccgctg
    16921 tgaaatacgg caggacccga ggtcgacttc ttcatccttc gccaaagcgg ccaacgcgtc
    16981 gtcgatgtgg cgaatcagga tccgccctga tttgacgtat cgacggtaga ggtcgccggg
    17041 caggtagccg tggccgccaa ggaactgctg cccgcggcgg accgtttcag taaacggtag
    17101 atactcgagg ctatgcagcg gattatggtg cacgaaggtt cgcatgggcc agtactgcgc
    17161 gatgacttcg ctggcaagcc ggatcatgcc gcgcaattcc atgcggcgcg gttcgagatc
    17221 ggcgggctcg tcggtgcgaa tcatcgggtc cacgtttccc ccttgatggc aaccgtggag
    17281 gagggagcag tcgtgtgaga ctcgaacatc cgggatggcg ccatccccag gatcagcagt
    17341 aagagcaaca ccagcatcag ggagatccat tccgtctgtc gcaaatcttc gtgccggatg
    17401 tccaggcgtg gccgaccgaa caccacctgt tggatgagat cggtgtagta ccacgaggcc
    17461 gtgagccaga cgagcatgat gatggcgaac ggcccggacg gcgcaaacgc gggggtgagc
    17521 agcatgccga ggaagccgga aaacaccccg aacggcggca tgccgagggc ggcaaggccg
    17581 agcagcgcca ggagagtgct gaaacgaggc atgggatagg cgagcccgcc gagggcccgg
    17641 aaatcgacat ccccgtaccg tgcgcggatg gcataccacg ccagcagaag tccgctggtg
    17701 gtgagcccca cggcactgag atagaccagg gcctggaccg gcgcggttcc cgtatcggcc
    17761 acataccacc acagcatgca gaagaatgcc gaagaggcat agcccaatcg cggcagggga
    17821 tgcgactgaa tcaaggcccg cagcgagcca tacacggcgc cggccaacgc caggagggcc
    17881 accgtctgga gtactgtccc ggagagtgac ggcagcaaca ggtacaggct atggaatcca
    17941 acggtcggca gaataaacgc caacaacgcg ggaagattgc ccggcagtcc gctgagtgca
    18001 gccacgaatc cgctgtgcag gggcagcagg ggcagcagcg tggcgcaggt gaccaacgag
    18061 gcgatcgttg cggctggtgc tggaagcgcc agcgccagca aggccgtgag gatgcccaga
    18121 ccgaatgaag ccatccctcg ccaggctgcc ggcgcagtgc ccggttgatg acgatagagc
    18181 aagccgcaga cgagaccgag gagcaggatg agcaagagct cgtgggtggg cgcgtgactc
    18241 gtgagaatgc ctagtgccac accgagcagg atcagagtca tcacccaggc tgaactgtta
    18301 tcccggtgca agggttgccc cagcagcgtc agaaacgccg ttgccgggag caggcacaac
    18361 aacgacatgg cggcagtcgc ttcgttctgt gccagggagg tgccgatgac ggcaagcaga
    18421 gtcagcccgg tcgtcgtcag ggccaccgtc ttcatgcgct gaagggcggc tctcatcagc
    18481 agggcgaggc ttgcgcctaa cagcggaacg gccaggagta gccagggtgt catccagctc
    18541 tcgatcacgg ctggactccg atcacggacg cagcagcgcg gcgagacatg cgcagtctga
    18601 atgcagtcac gatagccgtt tctccagacg atgcgcgacc tgtgtgacga cgcggccgat
    18661 gttgaggtac agctgatcca gatacaaccg gttcatgaac aggacataca ggcgcacgag
    18721 gaacgcttcg atccatccgg ggatggtgat ggtgcgtccg tgagcatggg catacagata
    18781 gacccagctc agaatcgtca acagcgtcgt gcccatcacc aggctgtcga aaagccgtcc
    18841 gggcagcgcg gcggccttga aatagaaggc cacctcttcc ggattcgggt acagaaaatg
    18901 ggtgaagctc tcgaccgcaa acagataggt gaagacgacg ataaccagcg tgaccagcat
    18961 ggcggccgat accttccagg aggccacggc gcgaatgcgc gtcagcgaga ggatcgcctg
    19021 cgaagacgtg acccagatga agaacaggaa gatcaccgtc ccttgtgatt cgagcaacgg
    19081 aattctcaac acgccgtgag tgaccaacaa aatgaccagg ggcagcaaca gcgtcgtgaa
    19141 gaaccccgtc gaccaggtca ggttggagaa ttcgctttcc tccgtctccc ggtcgatcgg
    19201 cgggaacgag ggttcctggc gggccttatg gatgacgttg ccgcagttca ggaacactgt
    19261 ccctttgaat agcccgtgcg cgatcagatg gaagacggca agggaaaagg ctccgaggcc
    19321 gcattccatg atcatgtagc ccatctgccc gatggtggaa aatcctaggg tcttcttgat
    19381 gtcattctgt gtcaacatca tggtggcgcc gagtatcgcg gtgagcatgc cgatcacgaa
    19441 gacgacatgc agcgtcgtcg ggctcaggcc atacagcggg gccagccggt tcagcaggaa
    19501 tcctccggcg ttgatgatgc cggcatggag cagcgcgtgg atcggagtcg gcgcgtacag
    19561 ggaccgcggc agccacgtat ggatgggaaa ttgggccgat tttcccatgg cgccgccgaa
    19621 gatgagcagg gtcaccgcgg tgacgccgtc catggtccag ccgagctcag gccagatcga
    19681 caaggtcacc ggcgtctcgg cagcgcgtgt gaacagcgtc tgaaattcga acgtgccgta
    19741 cagcgagtag gccaggacaa tgcccgcgag aaaagccgca tcgctcagtc gtaacgtcgt
    19801 aaacgtattg gacgcgccgg acaatgtcgc cgcatgcccg tgattgtgcg ccagcagaaa
    19861 taacagccag gagagaatct gccagaagat gaagagcatc accagattag cgctggaaac
    19921 catgcacagc aggacgctgg tggtgatgcc gagcataccc agataccggc ggtacccgcg
    19981 atcctggtac atgtacccca tcgaatagcg atagatcagc gtggtgacac cggtgatcag
    20041 gaccatcatg acggcgctga gccggtcgat gtagacgccg atggggaacg ccagattggc
    20101 gatggcggcc ggatcataca attggaacat gatcgggcca tccgacgtca cgacgatcag
    20161 aatgatgagc gagcccagga aagaggcggc gatggggaac aggccggatc gggcattctg
    20221 ctcctggtcc gcacgatcgc cggtcatcac gatgaaggcc gtgagtaacg gcaacagcgg
    20281 aacgagggct aagaaggaca tgcgaatccc ctgctggcca tgaaaagaaa aaggccagcc
    20341 gacggtcctt cacacaagga accaacgact ggcctgcact gtccccggcc tttcccgcaa
    20401 aggaaacacc ggcaagaccc tactgcctgt ctgagaacat caatggatgt gggtccgggc
    20461 cgcgcacgaa tcacggcctg tcgtcggcac caccggaaaa ctgggttaga tgtatctgtg
    20521 aaacccacgc aattgcaaga gaaaagtccg cgcaggcgaa ccggccgcat gggcgcgcca
    20581 cacttgatcg cggctcggat tgccgggtgt cggggtgtca catgggggtg gagtcctgcg
    20641 gcggccctga ctataatccg gtcgtccatg tctgtatcac cagggagcaa gatgaccgtg
    20701 ccggtgccca gcaagggaga aaaggaagcc gccgttcgta cggcgatcat caaattcgaa
    20761 caggaatttc tggggcgcgg ccccgacgag gtccgtgtgt tcatagtgcg ggacatgctg
    20821 gtcgtgcggc tgaagggggt gctcacgccg gctgagcgac aactggccaa aacggccgaa
    20881 ggcgtcgata tggtcaagcg gctgcgtcag aacctgatcg ctcaggggcg tgaacgactg
    20941 tgtgaacagg tggcggatct catcggtgcc aaaatcacgg cgttgttcac cgacatcgat
    21001 acggtggttg gtgagcgcat ctttgtcttc accctggaat ccgatctcga ggccaatttt
    21061 cggtgaggtg aggaagggtg caaaagccaa tgacgcaaca cagcctggag tccctcacgt
    21121 tcgagaacag ttacgcacgc ctgccggaag tgttctacgc gaaggtgaat ccgacgccgt
    21181 ttcgcgccgc gccgtttttg atcagcgcaa atcccgcggc gatggaatta atcgatctcg
    21241 acccgcagga agcgctgcga ccggaatttg ccggagtctt cggcggcagt ctgctggtgc
    21301 cggggatgga gccgctggcg atgttgtatt ccggccatca gttcggggtg tacgtgcccc
    21361 agctcggcga tggccgtgcg attcttctgg gggaaatcgt caacgggcga ggggagcggt
    21421 gggatctgca tttgaaaggc gctgggatga ctcccttctc ccgcgatgga gacggacgct
    21481 ccgtccttcg ttcggccatt cgtgaatatc tctgctgcga agcgatgcat ggactcggca
    21541 tcccgaccac acgcgcgctc tgcctggtcg gcagcgacga caaggtctat cgtgaacagg
    21601 tggaaaccgg cgccaccatc gtccgcatgg cgccttcgca tgtgcggttc ggcaccttcg
    21661 aaattttcta ttaccggaag cagcatgagc acctgcagcg attggccgat tacgtaatcg
    21721 agatgcattt ccctgatctt gcgcaggctg ccgacaaata tgtccgcttt tttgccgccg
    21781 tggtcgagcg cacggcgaaa cttatcgcgc agtggcaggc ggtcggctgg tcccacggcg
    21841 tgttgaatac cgacaacatg tcgatcctcg gactgaccct ggactatggg ccctatggct
    21901 tcatggacga ttatgatccg ggcttcatct gcaaccattc cgactacaat ggacgctatg
    21961 cgtttaatca acagccttac atcgggctgt ggaacctgag ttgccttgca caaaccctat
    22021 tgccgttcgc gcccaaggaa gacttgaaag cggcgctcga tggctaccag gctaccgtcg
    22081 accggtatta tcgggatcac atgcgacaga aactcggcct gcgagaagat cggggagagg
    22141 atgaggcgct gctccaggaa ttgaagtcgc ttatggtggg gagtcgggtg gattacacga
    22201 ttttctggcg cgaactcggc accttttcat ccgatcctgc ggcgaagaac gaacgcctgc
    22261 gggagcattt cctcaatccg gaccgcttcg atgtctgggc tgcacagtat cgtgagagac
    22321 tgcacagcga acagagtcgc gatgaagagc gacgggcagg aatggatcgc atcaatccca
    22381 agtatgtcct ccgtaactat ctggctcaaa cggcgatcga gaaggcgcag cagaaagact
    22441 attctgagat cgaccgcctc ctgaaccttc ttcaggatcc gtatagagac catcccggca
    22501 tggaatccta cgcagccgcg cccccgaact ggggcaagca tctcagtgtg agctgctcgt
    22561 cctgaccgac ccggttcgac ccgttctctg ataggaagat gagggcatgt gatgcgtttt
    22621 gaaaaactcg gcggcctgac ggttcgtcta acaggcggaa cagacggcaa gggcgggggc
    22681 aatggcccct gggtgatgtt gctccatgga ttcggcgcat tgggcgatga cctggttccg
    22741 ctcagtgaat atctggacgc acctgcaggc acgcgctttc tctttcccga agcgccgatc
    22801 ccaattccga tgggcttcgg cgattcgcgc gcctggtgga tgatcgatat ggcccgcatt
    22861 caggccgatc gggcggcggg gaagatccgc gacatgtcag gcgaaatccc gcgtggcctg
    22921 cctgaagccc gtgagcgggt gaaagccttg ctggaggatg tacataagaa actcggggct
    22981 gatcctgcgc ggactctgct gggaggattt tcccaaggcg cgatgttgtc ctgtgatgcg
    23041 ctgctgcata gcacgcttcc atacgccggg ctgatccaac tctcaagcac gctggtggca
    23101 aggcaggaat gggcgcctct gctcacgaaa cggaaggggc tgccgcttta tcagagtcat
    23161 ggcacgcagg atcccattct gccgttcacc atggccgagc ggttgcggga tgaattccat
    23221 ctggcgggcc tggtcgtcga ttggcagccg ttccggggag ggcatgaaat tccagagccc
    23281 attctgcgcc gtctcggaag cttcatcctg aaaacgctcg tgtaacacat tgtgcaagct
    23341 ctagggaaaa ccgtctctga ttgcatcccg aacccctccc gaatggagcc gtctgctgaa
    23401 agggtgccgc tgggtcctat atggtgatga tgatggcaca tgatcgcagc aggacagagt
    23461 acctctccac ccagtcggcc tacgatgaat gggccgagga ttatgatgac ggggatccca
    23521 ccgttcttct cgatcagcca tttcttctgt ccatgctgca gccttttgca ggatgccgaa
    23581 ttctggatct ggggtgcgga accggtcgct atcttcgttt ggcgagtcac gaagccgcgc
    23641 tggtcggcct ggatttgtcc cgaggcatgc tggagcgcgc caggcgccag acaccaccgg
    23701 ccactggagc gacctgggtg caagggtctg ttgagcgcat cccgtttact tcagagagct
    23761 tcgaccgtat tgtctccggt ttggtgttgg atcatgttca cgacctggcg gaatttttcc
    23821 ggggcatcgg gaccatgctc cggccaggcg ggcgtgcgat cgtgacggcg gttcatccgg
    23881 agatgcaacg gaaaaccggg ccgacggtgc ggttcaccgc cgcagggcgt gaatatcgta
    23941 cggaaggaac catccacgag aaggccgcca ttatcacagc ccttcaggag gcagggctct
    24001 tgatcgagca actgcaggaa ccaccggtga cagagcgact catcgcccgc cgggaggcgt
    24061 ggaaagatcg gctcggctgt ccggcactgt tattattggc tctgacacgt gcggcggatt
    24121 ctcgtcatga ccattgatgc caccatgttt gaattacagg gtaccgatca caagcgcctg
    24181 cgcgggaacc gcattctagg caaagaccgc cagatcttgt tcatcacggg gtttctctcg
    24241 aagcgctggg gcaacaagag caaggcactc gcgcaatggt gccaggaccg aggatgggga
    24301 ttttgttgtt tcgactttcg cggctggggt gactccgaag ggcagtgggg agactatcgc
    24361 ctgctccact ggctcgagga tgcggaagcc gtcacgaatc tgctggccga tggtccgcca
    24421 gtgacgatcg tcggcaattc cctcggaggt tggctggcgt ggctcgttgc gcaagagcaa
    24481 ccggccgtcg aggaactcat tctgatcgcc ccggccttca acatgatgga cctgcgagcg
    24541 gcgcaaatct ctgctgagcg gcgcgaacaa tggcagtcgg ccggctccat gccctgggat
    24601 gatgaaccct tgcatcgaga ggcgccgatt ccctggcatt gggtagaaga cagccagacg
    24661 ctctggcgcc gccgcctcac catgccgcgc cgcgtcaaga caaccattct gcatggcctg
    24721 caggatacgg tgatcaagcc ggaaggcagt tgggccttcg tgcagcatgt gctgtcgcag
    24781 gatccggagt tccccatcga attgctgctg aaaaccggcg atcatcggct gagcagtccg
    24841 gagcatttgg acacattccg gcggctggtg atgaaggaat aaccatgttg gtgttaatcc
    24901 acaaagaatg cggtggtccg gcgctggaag aatcgccggt cggcgaagtc tgcgcggttc
    24961 cggtcgatcg gtttccgttt tcctgcttca gctgtctgga agaaatcatc gacgaatcgg
    25021 aattgcggct catagaagat ttgggcatct gacccataga ggaaggcgga catttcatgt
    25081 catcgttagg cgcacataac agcggaccgg attcagaagg tccggacgtt cccgaaccct
    25141 cccatgccga aaaggccagg acgctggtgc atctgcagca gacgggcggc ctctccaccc
    25201 tctcacgcaa gcaaccgggc tggccgttcg ggtcggtgat gccgtatgga ttggacgatc
    25261 agggccagcc aagttttctg atcagcacca tggcgatgca cacgcagaat ctgctgggag
    25321 atccccgcgc gagcctgctc gtgacaccgc cggagagcca acgcgatccg ctgggcgcag
    25381 ccagagtcac gctcatggga tcggtcacga aggtgcctaa agatgaggcg gcaccggtgc
    25441 gagaacggta tctggcccgt catgccaacg cagcctactg ggtggacttc gatgacttcg
    25501 cgttttttcg catggcgctg gcggacattt attttgtcgg tgggtttggt tcaatgggat
    25561 gggttgcacc ggctgagtat ctggcggcag cagtcgatcc tttggcagag accgctgcgg
    25621 acctcatccg cgagatgaat accacgcaac aggagacact gctgttgctt gcccgcgaat
    25681 gtggcaatct cgatgcgcag caggcgagca tcaccacgat ggaccgattg gggtttcacc
    25741 tgcgtgtgaa aacacccgag cgtatgcagg gtgggcgatt cgccttcacg aatccagtgc
    25801 gcaccgcgca ggaagcccgc gccggtgttg ccgatctggc cgcgaaggca aaggccggcg
    25861 gccaagtgct tcactcgctg taactgcgcg tggcgggatc ggcggggtgt tctgctagag
    25921 agccaagatt acttcccgcc agtggctcga acgatttccg cgcgtaacgt ttccgaatgc
    25981 ggatttttga cctcatggcg gatgatgata tccgtcggcg tgaccggctt accgtagtag
    26041 gctctgctcc attcatcccg cgagatcagc accgcccctt ccaacgacac acccgcgaac
    26101 aggcccttgg cccgcacgaa tgacaataga tccgcactga ggttgggcgt cgtcgcgccg
    26161 gaaacacccg cgccgaccgg tccgacggcg accgatccat ctgcccctag tttgaaattc
    26221 cccagcagca acgaatctac cccgcgttgt gtcagaacca gcaacacgac ctccgacatc
    26281 tgcgcgccga attgaaagcc gaagctggcg gcccccatgg tgaagaaggc cggctcgctc
    26341 cattcgccgg tcttgtcgtc cttcgcgacg aagaccccgc tgccgccggc tgcgccatag
    26401 atcaatgcgc ccttcatata ttgcggcacg atgaacagac ccttggcctc tgggacgtgg
    26461 tcgcgaaacc aggtcatgtt ggaatcggcg aggaagttcg acagggtcat gcgcgactgt
    26521 tccaccaggt cgcgctgctc gcgatcgtct gcaagggcgg aggcgacacc agtccaggcg
    26581 aggaatggca ggagcagtgc caggatgatg cggcaagatc ttcgctgaat ccgtgcgtct
    26641 ggaatcatgc ccggagctcc ctcgcgcggt t
//
LOCUS       DAOQPD010000054        25325 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_919_length_25325_cov_21.872299, whole genome shotgun sequence.
ACCESSION   DAOQPD010000054 DAOQPD010000000
VERSION     DAOQPD010000054.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 25325)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 25325)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25325
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_919_length_25325_cov_21.872299"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1550)
                     /locus_tag="PK063_12635"
     CDS             complement(<1..1550)
                     /locus_tag="PK063_12635"
                     /inference="COORDINATES: protein motif:HMM:TIGR01194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_function: GO:1904680 - peptide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015833 - peptide transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic peptide export ABC transporter"
                     /protein_id="HMZ97946.1"
                     /translation="MMKLYRFLLFLLRDARTMMILMVMTGLLAGLSSVGLLAVINKLI
                     NGPGTASELFAVAFIGLAVLKVGSNYLSQLLLVTFAQKTILKLGMDLCWKVVRAPYRT
                     LERRGPHEILATLTDDTNALAWAVNGLPGLAINVAILGGCSLYLAWLSWQAFLGVVIL
                     AVLGLLGYRQLYNRVLQSSLAVRDSKGVLFEHFRSLTEGMKELMLHRGRRETFVEEDI
                     RQAADALRRHNLTTTKQYLVTDSWTQVLFYGLIGVILLLFPRVLSLSGESLTGYAFAM
                     LYMIGPMWGLLGMVPTLSRGQVALEKIESLGLALDEGGREGGAERPMAQGRPCVEFSN
                     AVFAYESKGEDERSFRLGSLDLSIRAGELVFIIGGNGSGKSTFVKVLTGLYLPQQGQV
                     TLNGEAITSATQDWYRQHFAAVFSDFYLFKKLLGLDPSLVASQADGWLKTLRIDHKVR
                     IEQGEYSTVNLSQGQRKRLALVTAMLEDRPFYVFDEWAADQDPQYKDVFYGELLPNLR
                     ARGKGVIVV"
     gene            complement(1604..10966)
                     /locus_tag="PK063_12640"
     CDS             complement(1604..10966)
                     /locus_tag="PK063_12640"
                     /inference="COORDINATES: protein motif:HMM:NF003417.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HMZ97947.1"
                     /translation="MVRHPPVTIPAGDTLLDVLRWRAEHQPDQTAYVYLREGLSADSV
                     LTYRDLLTRARSIASYLQARFAPGDRLLLVYPPGLEFVQAFWGVLYAGLIAVPVPPPD
                     AFRLKAGVARVQRLAEDAGAAGALTTAQMLETLRSQELVASLHQWVSSDQALSADSSG
                     WTDLQQLPTHLAYLQYTSGSTSAPKGVMVSHGNMTAQSRCITDAGGYDAGSVTLSWMP
                     HFHDYGLVKGIIQPAWIGRPSYLMSPLTFLKRPLRWLEAIQRYAVTHSGAPNFAYRRC
                     VEATTPEERAGLDLSQWQVASCGAEPIAPDTIQRFAAAFAPSGFQREAFFPAYGMAEY
                     TLLISLKRRGAAPTVTTLDAAALEKGAVIEAVADDKPVRKVVGCGMPVGDTRVVIAHP
                     ETRCRCAVQQIGEIWLSGASTTQGYWNKPDETSHTFGASLADTGDGPFLRTGDLGFVK
                     DGEVFVTGRFKDLLIVRGRNHYPQDLERTVESCHGALRAGGAAAFTVEEAGEETVVLV
                     QEVERQASPCSTEDLAAAMRAALSEQHDLHASTIVFIKAGSLPKTSSGKVQRRACREQ
                     YLAGRLSIIGTSVAPHPVAQSSPAPIHTDAWQRLSGEARTSAILQTVQKLLADRLGCM
                     PQAIAVDRPIHLLGLDSLMAADVLHRLEESFHLSLSLSALLGGATPADLTTMIERGLA
                     GESRAQSVAAIADPAIATVFPLSENQAALWFLSQLDPDSAAANVSVLLPLPSDLKADR
                     LRAALEAIGDQQAMLRTTFETQEDGPVQRIHDRMPLSWSEIDSSTWEWPQLRGESVKA
                     AAVPFNLTQGPLWRATLFHGGQQSWLLLVAHHIVVDGWSMMQLVDDLKRRCEVAGSCS
                     SEHSPEPQDRPAPYREFVEWHRAILEGEEGSRLGQYWKAKLAGELPNYDMLYDRPETT
                     VEPSHYAWHAFHIDENLTRRLKKFARTEGTTLYAVCLSALQILLTRYTAQEDTAIVTP
                     VFGRSRARFARTVGDFVNMLVLRESLQSELTGRELLARTKQTLLDALAHQDYPYARLV
                     ADIRSARQGPRAPLAQVLFVLQQFKLLAELDLRMGVSTGAASNVGFLAWDAYVIPQQS
                     GQFDLCLELAESKDGLSGYVEYKDALFGEERITRMQEHFVRLLQELVSHPTDRIVSLP
                     LMSEAETQQTVLAWGQPSGTADPELCLHRMIEKQARRTPEAVAVEQGGQSLTYGELDT
                     RANRVAHYLRRRGVEPGVVVGLCLERSLNMIVGLLGILKAGGAYLPLDADYPTERLEY
                     MLRDSQVRVLVTQQDQLVRLPATNPHTICLDSEWAQIAKCPDSPIDVTDALDNLAYVI
                     YTSGSTGHPKGVMIEHRSIANYVRAITKIVDLTGEDRVLQFASLSFDTAAEEIFPCLA
                     AGATLVLRTATMVDSVSGFLDRCRDLNLTILDLPTAYWHELVTRMALEQVAFPSSIRS
                     VIIGGERVLPQIVQRWTDLIGATVRLINTYGPTETTVAVTWSDLTGLEAHDELIGDLP
                     IGRPIPHTSVFVLDRNQQPVPVGVAGELYIGGVGVARGYRGRPDLTETQFVPDPFSKQ
                     PGARLYRTGDLVRWRPDGQLDYRGRADRQVKIRGYRIELEEIEAVLNRHQDLERAVVE
                     VREDQPGDKRIVAFMVPRPNNRLGLVQLREQLRSQLPAHMIPSTFIEMETLPLTVNGK
                     VDRKALQVAADSRASKVELTSQYLAPRTPTEQVLADIWGEILQLKDVGVHDHFFELGG
                     HSLLATQLVSRVQSLFRITLPLRQIFERPTIATLAEVITQAQAGANSHQGESGYVITR
                     ARRGIPLPLSFAQERMWFLYRLSPDAVAYNIPASVRLHGPLNKPALRWAVAELVRRHD
                     ALRTTFAHVDGQPRQIIQDVLDPTWTEEDLRGVPAELREPRALELATAEARRPFDLEQ
                     GPLLRVFLIQLGDEDQIVILNTHHIISDQWSYGIIARELVTSYNAFCAGRPFAVQPDL
                     AIQYADFAQWQRGWLTGPVLEEQLAHWKTKLVDLPVLTLPTDRPRLPVHSFKGDHVSL
                     DLSWSLINRLKQLSVREGVTLYMVFLAGFFGLLHRLTQQKDLVIGTPIANRNRLEIEE
                     LIGTFVNTLVLRADVTGELTFRDLLRKVRDLSLDAYAHQDIPFEKLVEELRPDRSQGG
                     LPLVQVLFNFANTPFARTEFHQLSWTPYEVSRGAAQLDLGLSIDPYASRKAYLEFNTD
                     LFDRASAERWISQYRQLMETVAEHADAELGRVSILTGQEQHRILREWNATDRPVDQGL
                     CFYQLFEAQVSRTPDAVAVRFEGREWSYAELNRRANRLAHRLRECGVGPDAVVPVFLE
                     RSPDLLISLLAVMKAGGAYLPLVPGLPIRRLAAMIEASHAAVLITESALLGGLPQHQL
                     PVLCLDQEAEVLARQAEENPSPRSGPEHLVYVLFTSGSTGQPKGVEIEHRALVNFLRS
                     MQQEPGITHRDVLVALTPLSFDIAGLELYLPLLVGATIILANRQQAMDGAWLQRELDH
                     GAVTMLQATPATWRMILQFGWKGGRGVKVLCGGEALPRELAQELLARAGSVWNVYGPT
                     ETTIWSTLERVRNAERTISLGRPIANTQVYVLDGNLEPVPVGIPGELYIGGMGLARGY
                     RGQSQLTAERFITNPFKAGERLYRTGDQVKWLPDGRLDYVGRIDHQVKLRGFRIELGE
                     IESVLGNDATVKQAVVIVREDSPGDKRLVAYVAPREGSACDPSSLRRALREVLPDYMV
                     PAAIVPLTEFPLTPNGKVDRASLPAPAAEPVHDGAQAIEPRNRVELQLVAIWEQVLGI
                     TPIGVRDNFFTLGGYSLLALRMFSAIEQTFGTRLPMAVLFQAPTIEQLADVLADEGCT
                     VRWRSLVAIQPEGKRPPLFAVPGVGGNVLVFARLAKLLGDDQPFYGLQARGLDGKEKP
                     FMRVEEMAAHYIEEIRSVQPHGPYFIGGTCTGGLAAYEVAQQFTAQGEEVILAVMESW
                     HPRSYLNHWSRPPYLLWPLLFVWMKVTTYLRLMRRLPADEWASFWKGKLKRMWNLMHH
                     TEAAEHQDEFLYKDQVTYATFHAVARYELKPFRGQVLNVIASKHPLTNSSDDTRLVFG
                     EWAMGMSRTVYLPAEDSGRLFVAPHVQELARQLKAFWQEAEAVYRKRPDGQGDGPTTK
                     AA"
     gene            11248..11335
                     /locus_tag="PK063_12645"
     tRNA            11248..11335
                     /locus_tag="PK063_12645"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11282..11284,aa:Ser,seq:cga)
     gene            11550..11684
                     /locus_tag="PK063_12650"
     CDS             11550..11684
                     /locus_tag="PK063_12650"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97948.1"
                     /translation="MFEQTDAALVMTLLALGGIALMADEKLGTTCLQMVRWIRTRGRH
                     "
     gene            complement(11681..13186)
                     /locus_tag="PK063_12655"
     CDS             complement(11681..13186)
                     /locus_tag="PK063_12655"
                     /inference="COORDINATES: protein motif:HMM:NF022525.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2779 domain-containing protein"
                     /protein_id="HMZ97949.1"
                     /translation="MLILPEPAARSSYRLSKSRYLSGLQCHKRLYLEVHAPGLATKPD
                     AATQAILDMGTDLGELARQRFPGGRLVTAGYRQSQEALAQTAELLQDPTVPAIFEGAF
                     QFNQVLVRVDVLQRVGVNELGQPTWRLVEVKSSTKVKATHVDDLTIQSYVLEGLGLVL
                     AEICLMHVNTQYVFDGRYLDLDQLFGLRSLTETVRPRLPEVPARLAAMQAMLEGMSAP
                     AVMPDEHCQSPYECPFWTHCIEHKPARWIYHLPGSSKTVVQLRELGVETIDEIPDHVA
                     LTPVQRRVKDNREWIGEGLRSALETIVYPVHHLDFETFMPAVPKFVDTRPYQVIPTQW
                     SNHIEQYDGTLTHAEFLCRDERDPREELAITLLESLGQTGSICVYSSYERSVLERLAE
                     DFPSLRKDLKRVVARLWDLHVIIRDHYYHPAFEGSYSIKAVLPAVMPSLSYADLVIRD
                     GGVAACEYSRMIFTVTDWIEKAQIQEALLRYCERDTLAMVELRRELKRRAG"
     gene            13289..14626
                     /locus_tag="PK063_12660"
     CDS             13289..14626
                     /locus_tag="PK063_12660"
                     /inference="COORDINATES: protein motif:HMM:TIGR00797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HMZ97950.1"
                     /translation="MAQGIAQIRRSVLTLALPVTVSSLLQRAEGIVAVFLVGGLGAVP
                     IAAVGLGQLLAFIATTLVSGLSVGSNVVMAQLWGARRYDDAGHAARHFLGLSILIALG
                     LLSFGLLVNRLAMEMLGAQADVIRLALPYSNLIFLLIPFTILLQVLSSILQGTGDTKT
                     PMYAMIVVNLLHIAIAIPLIYGHWGLPALGINGAAIAVGIAEATGCLYLFTRCRPMLR
                     GSHRFRFDLIRTIWHVGAPVSGERVVQQAGILLYTKIVLMYGTVAYAAHQVGLSIESL
                     SFLPGYGFAIAAATMVGQSIGAGKYTRAKLETWEANRLAAYMMSAMGVVFFLFPYALL
                     RAFTSDEAVVELGTLFLKIVALLQIPLALTMVVAGSLRGAGDTRFVMIATMIGMWGVR
                     IPLAIVAGYWLSMGVLYVWLAMIADWTVRMALMLWRHRSERWRSIQVLRSSPT"
     gene            complement(14632..15999)
                     /locus_tag="PK063_12665"
     CDS             complement(14632..15999)
                     /locus_tag="PK063_12665"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: protein motif:HMM:TIGR00745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HMZ97951.1"
                     /translation="MKQIMVVGAGSVGGFFGAHLAKNNPNVSFLLRPRTLEAVKRNGL
                     TIKSAKGNFTVHPPAASDPRELATPDLIILAVKAYDLDEVMTQLEPVLTDRTVILTLQ
                     NGIDTEDRIISRLHRDCVVGGVAFIYSKIVEPGVIEHYKRGGVAIGELMGHKSERVSQ
                     IADIFKQAGISCQLSEDIRKSKWEKMCWNCVFNPLTVMIDDKVAKALDHPEMAGVIRQ
                     IVGEVAAVSAAVKVPLAPDMAEKVVKWTQELRDIHTSMYDDWKAKRPTEIDYLNGYIV
                     RVGRELGIPTPVNEALTAMVKTITEKELSGPSIVRIDGAVVQPVSLTRTALGQLPREQ
                     RVDDISELMPSMRGRAIRVKGLLEVPALAVDADHVTFHSVDGKYAATLTLQQAQDFGL
                     LLYELDGQPLPDGKGGPYRLVTPGLGDLCANVKAVGRIEVRAGSGKDTRPAVRPPECA
                     VDGQS"
     gene            16084..16815
                     /locus_tag="PK063_12670"
     CDS             16084..16815
                     /locus_tag="PK063_12670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent deacylase"
                     /protein_id="HMZ97952.1"
                     /translation="METGSTLGLVRHKLSTARSVTILTGAGISADSGVPTFRGADGLW
                     RHYRAEDLATPEAFARDPRLVWEWYNWRRELIATKRPNPAHEAVASMEQRFKQFWLIT
                     QNVDGLHGDAGSRQLSEIHGNLWKVRCTRCRDIVENRGVPIAMLPLCRSCGGLLRPHI
                     VWFGESLAEEDLDRSAAALQSSDVCLIVGTSGMVYPAAGFGAIAKQAGAFIVEINLDA
                     TPHSNLADATLQGRARDIVPLLLEA"
     gene            complement(16801..17526)
                     /locus_tag="PK063_12675"
     CDS             complement(16801..17526)
                     /locus_tag="PK063_12675"
                     /inference="COORDINATES: protein motif:HMM:TIGR02252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HMZ97953.1"
                     /translation="MSQSRIQVVFFDAADTLFHIQGSVAEIYLQHAERHGFRKTPDSL
                     AAIKAAFARSFRDAPPPVFAATEPGGIKQSERLWWFDIVHNVFYRVGMFEKFDEFFED
                     VFARFAQAESWKLFPETLDVLKTLKDHGYELGIISNFDSRLFSVLRGLGIADFFDTVT
                     ISSLAHAAKPSARIFEQALEKHAVDPEDALHVGDSARDDVKGAIAVGLTGVLLARGLP
                     PEGSNGATIATLNELLPLLSRLQ"
     gene            17739..18866
                     /locus_tag="PK063_12680"
     CDS             17739..18866
                     /locus_tag="PK063_12680"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ97954.1"
                     /translation="MGSTIFVIDNSPAVQRMVEQLSAPDGHRVLAFQDGPSALEAARS
                     QCPALIIADYHLEQMTFSGFCKEIGRQDNLAETLIVSIVDSADRLDESKLRALGVRAF
                     LKKPFQREQLLETIQSILSKPEGSRSQKPAKSRTWPPATTGADDDDETSPDASAEHTS
                     RLAEKKEQPPMSSTAPATRPTGEDLMKGLVEHLLHSTTVKADRAITELLPAAVAKEVA
                     GQLGAALSKAVQAEVSKQVAEALAPERIQNTLREMVQMELKRQSESQRAGMESSIRQA
                     VTELAPGLMAQSSEKLLPGLTDAGVKQHLPEALQSQRDLITDGVKKEVEQVAATYARQ
                     AAEDIVRELAKDPILQAVQRVVPDVAETQIRAEITRLSSPD"
     gene            19189..21951
                     /locus_tag="PK063_12685"
     CDS             19189..21951
                     /locus_tag="PK063_12685"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HMZ97955.1"
                     /translation="MSTPQLDKTYNPHDVENRWYQRWIDAGLFHADPAQTGQPYSMVI
                     PPPNVTGSLHVGHALNNTLQDILIRWRRMQGRNVLWMPGTDHAGIATQNVVERQLQAE
                     GTSREALGREAFLSRVWQWKEKSGGTIIGQLKKLGASCDWQRERFTMDEGLSEAVREV
                     FVRLHQDGLLYRGERLINWCPRCLTALSDIEVEHEEATGKLYTIRYHLVDDPTQFLLV
                     ATTRPETLFGDTAVAVHPEDDRFRHLIGKHVRLPLTSRAIPIVGDSILVDREFGTGAV
                     KITPAHDFNDFEAGERHGLKRIKILDLHAHLRLGGSLADPAVAEAVENLPVAKARPKI
                     EQFLTDQGFLEKSEPHKMALGKCYRCKTVVEPFLSDQWFVKIKPLAEPAIQVVEDGRV
                     RIIPEAWKNNYLGWMRDIKDWCVSRQIWWGHQIPAWYCETCSGTPFLRRSSDGAPLIP
                     SDAAAIVAKTKPDSCPLGHRDALVQDPDVLDTWFSSALWPFSTLGWPKQTPELKAFYP
                     TSTLVTGLDILFFWVARMIMMGLKFMGDVPFRDVYIHALVRDAEGQKMSKSKGNVIDP
                     LHVMEQYGTDALRFTLAAMASPGRDVKLAEERIEGYRNFTNKIWNAARFLLMHLDGER
                     TDVAPAQRSFPDRWILSRLNTAISTVTQELEQYRFDRASSAVYQFIWHEYCDKYIEMV
                     KPALKDANSEQAKSTRQTLAETYETMMRLLHPFMPFITEEIWQTLPHEGTSIVRKSFP
                     TTRKDWESEEVEQEFALLEECRALMNQERAILGYPAGKRLHFKVHGKTEAIASILQKH
                     KDLIEYMENVDNLWIAKTFDVSNPGGLLILTSGSIQVRTSMEDADLGKAEENVQKQIK
                     LLQKEVDRTQQKLGNPDFVAKAPPDVLTEHRERLQRESHMIQLFQQALDQIKLYTLER
                     TRIEHP"
     gene            21938..22819
                     /gene="nadC"
                     /locus_tag="PK063_12690"
     CDS             21938..22819
                     /gene="nadC"
                     /locus_tag="PK063_12690"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0019363 - pyridine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HMZ97956.1"
                     /translation="MSTPSPQTILNAVQQALAEDLYHGDVTTSALFPRPLRATATIVA
                     HQPMTVAGVAVAREVFLAVDPSARITKAVKDGSAVKSGTTVLTVQGDVRSLLMAERVA
                     VNFLQQLSGIATLTAQFCAAVRGYPTRILDTRKTTPGLRALEKWAVQLGGGKNHRFSL
                     GDGVLIKDNHLAVLRSTGIDVAGACRLARAGAPHGLRIEVEAKTMQEVKEALAGKADI
                     ILLDNMSPAQVRQAVTLIKQRALVEVSGGMTLQTVAAMAQVGADFISVGALTHSAPAA
                     NLSMDLSAQRGRRGRSH"
     gene            22803..23675
                     /locus_tag="PK063_12695"
     CDS             22803..23675
                     /locus_tag="PK063_12695"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: protein motif:HMM:TIGR00121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HMZ97957.1"
                     /translation="MGGPISDSPISPPFDIDRLQASLRTHAFGRPLRYSASTASTNAD
                     ALASLQQSATQPAPHGMVILTDCQTAGRGRRGRTWHSPPQGNLYLSVIVVPRPVATGT
                     TPWLTWIPLLSALAGADCLSQQTGLPVSVKWPNDLLIHDKKVGGILCEQTTTPDRTMA
                     IIIGIGLNINAPLNTFPEDLQQGATTLAAEAGHEFDRVAILADLLFRLEQRLNRLFLE
                     GPAGMIDEFTQRCSTVGQTVRVTLEEKGMVQGIAESIGPDGCLRLRVTSNESPSLPST
                     LLEVRSAEVVHLRG"
     gene            23711..24481
                     /locus_tag="PK063_12700"
     CDS             23711..24481
                     /locus_tag="PK063_12700"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HMZ97958.1"
                     /translation="MLLAIDIGNTNVVCGLFEGSTLRGHWRMATESRRTDNEYGILLL
                     NLLQNAGFTPDQITGCVLSSVVPALTATFDSVVQEYFHRTAVIVGPETDSGLTLRYAN
                     PKEIGSDRIVNAAAAYARYHSDVIIVDFGTATTFCAVTKSAEYLGGVIAPGLGISADA
                     LFARTAKLPKVEIIRPKTVIGKDTIGGIQSGLLFGYVGLVDGIVRRMERELGRTSRVV
                     ATGGLATVIAQETETIQEVLPFLTLEGLELLYRRNRLA"
     gene            24610..25173
                     /gene="grpE"
                     /locus_tag="PK063_12705"
     CDS             24610..25173
                     /gene="grpE"
                     /locus_tag="PK063_12705"
                     /inference="COORDINATES: protein motif:HMM:NF010748.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000774 - adenyl-nucleotide exchange
                     factor activity [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0051087 - chaperone binding [Evidence
                     IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HMZ97959.1"
                     /translation="MQSMSEDEKNVHSIDNLDSSDEPSSATIDGASELQQVLDAKAEE
                     CKAAHEKYLRLAAEFDNYKRLAQRDQREQIKFGNEQILKELLPVVDNLERAIKSAKGA
                     GSVDALTEGVELTLKQLVGALSKFGVKAVESVGQVFDPATQQAVAQVPSDTIPENHVV
                     EEYQKGYLLQDRILRAAMVTVSTGAAN"
BASE COUNT         5383 a         7908 c         7073 g         4961 t
ORIGIN      
        1 acgacaatga cccctttccc tcgggcccgt agattcggca acaattctcc gtagaagacg
       61 tccttatatt gcggatcttg atcggcagcc cattcatcaa agacgtaaaa cggccgatct
      121 tccagcatgg cagtcaccag ggcgagacgt tttcgttgcc cctgagacaa gttcaccgtc
      181 gaatattcgc cctgttcaat acggaccttg tgatcgatac gcagggtctt cagccatccg
      241 tccgcctgac tggcgactaa cgacgggtcg agtccgagca gctttttaaa gaggtaaaaa
      301 tcagaaaaga ccgcggcaaa atgttggcgg taccagtcct gagtcgcgga cgtgatcgcc
      361 tccccgttca atgtcacctg cccctgttgc ggcagataga gtcccgtgag cactttcaca
      421 aatgtcgatt tgccgctgcc gttcccgccg atgatgaaaa ccagctcacc cgcgcgaatg
      481 gaaagatcca gcgaccccaa acgaaatgac cgttcatcct cgcccttcga ttcgtaggca
      541 aacaccgcgt tggagaattc cacacagggc ctgccctgcg ccatcggacg ctccgctcca
      601 ccttcccgac cgccttcatc cagcgccaac cccaacgatt caatcttttc cagcgccacc
      661 tgcccgcggc tcaacgtcgg caccatgccc agcaggcccc acatcggacc gatcatgtag
      721 agcatggcga aggcataccc ggtcagcgat tcaccggaca gcgaaaggac gcgaggaaaa
      781 agcaggagga tgacgccgat caaaccgtag aacagcacct gggtccagga atccgtgacg
      841 agatactgct tggtcgtggt caggttatga cgccgcagcg cgtcggctgc ttgccggata
      901 tcctcttcga caaacgtttc ccggcggccg cgatggagca tcagttcctt catgccttcc
      961 gtcaaactcc ggaaatgttc gaagaggacg ccttttgaat cacgtaccgc caacgacgat
     1021 tgcaggacac gattgtagag ctggcgatac ccgagcaatc ccagtacggc cagaatcacc
     1081 acgcctagga acgcctgcca ggataaccag gccagataga gcgagcagcc gcccagaatc
     1141 gccacattga tcgccaagcc cggcaacccg ttcaccgccc aggccagagc gttcgtgtcg
     1201 tccgtcaggg ttgcaagaat ctcatgcggc ccgcgacgtt ccagcgtgcg atagggcgcc
     1261 cgcaccactt tccagcagag atccatgccc aattttaaga tggtcttttg cgcgaaggtg
     1321 accagcaaga gctgggagag ataattcgac ccgactttga ggacggccaa cccgataaat
     1381 gccacggcaa acaactccga ggcggtgccg ggcccgttga tcagcttgtt gatcacggcc
     1441 aacaaaccca cgctggagag accggccaac agccccgtca tgaccatgag gatcatcatg
     1501 gtcctggcgt cccgaagcag aaacaggaga aaccggtaca acttcatcat cgtatcgtgg
     1561 cttccgcgta ggggtgactc atggctggca atcgtgggag aagctatgcg gccttggtgg
     1621 ttggtccatc accctgaccg tcaggccgct tccggtacac ggcttccgcc tcctgccaaa
     1681 acgccttgag ctgacgtgcc aattcttgca catgcggcgc gacgaacaag cgtccggaat
     1741 cttccgccgg aagatacacc gtccggctca tgcccatcgc ccattcgccg aacaccaacc
     1801 gggtatcatc actcgagttc gtgagggggt gcttggatgc gatcacattc aacacctgcc
     1861 cacggaaggg cttcagctcg taccgcgcca cggcatggaa ggtcgcgtat gtgacttgat
     1921 ctttgtataa gaactcgtcc tgatgctcgg cggcttcggt atggtgcatg agattccaca
     1981 tgcgtttcaa ctttcccttc cagaacgacg cccattcatc ggcaggcaac cggcgcatca
     2041 gccgaaggta ggtcgtgacc ttcatccaca cgaacaacaa cggccagagc agatagggcg
     2101 gacgactcca gtggttcagg taggatcgtg gatgccagga ttccatgaca gccaggatga
     2161 cttcttctcc ctgtgccgtg aactgttgtg cgacttcata ggcggccagg ccgccggtgc
     2221 aggtacctcc gatgaaatag ggaccgtgcg gctgcaccga ccggatctcc tcaatgtaat
     2281 gggccgccat ctcttccacc cgcatgaacg gcttttcttt gccgtcgagg ccgcgagcct
     2341 gcaatccgta gaaaggttga tcgtctccca ataatttggc gagccgcgcg aacaccagta
     2401 cattacctcc aaccccgggc acggcaaata gtggtggccg ctttccttcc ggctgaatgg
     2461 ccacgaggga gcgccaccga accgtgcaac cttcgtcggc caggacatcc gccagttgtt
     2521 cgatcgtcgg cgcctggaac aaaacggcca tcggtaaccg cgtcccgaat gtctgctcaa
     2581 tcgcgctgaa catgcgaagc gccagcagcg aatagccgcc caatgtgaaa aaattgtcgc
     2641 gcacaccgat gggcgtaatc cccagaacct gctcccaaat cgccaccagc tgcagctcga
     2701 cccgatttcg gggttcgatc gcttgggcgc cgtcatgcac cggctcggca gcgggcgccg
     2761 gcaaggacgc gcgatccacc ttcccattgg gcgttaacgg aaattccgtg aggggaacaa
     2821 tggcagccgg caccatgtaa tcaggcagca cctctcgcag tgcccggcga aggctggatg
     2881 ggtcacaggc actaccctct cgcggcgcca cataggccac aagacgttta tcgcccggcg
     2941 aatcttcccg cacgatcacg accgcctgtt tcacggtcgc atcattcccc aacactgatt
     3001 caatttcacc cagctcgatc cggaacccgc gcaatttcac ctggtggtcg attcgaccga
     3061 cataatccag tcgtccatcg ggcaaccatt tcacctgatc gccggtgcga tagagtcgct
     3121 caccagcctt gaacgggttg gtgataaaac gctccgccgt caattgagac tggcctcggt
     3181 agcctctggc gagacccatc ccgccgatat acaactcacc tggaatcccg acggggaccg
     3241 gttcgagatt gccatccaat acgtagacct gcgtgttcgc gatcggacgg ccgagagaaa
     3301 tcgtccgttc agcgttacgc acgcgttcca atgttgacca aatcgtcgtt tcggtcggcc
     3361 catagacgtt ccatacggat ccggccctgg cgagcagttc ctgcgccaat tcgcgcggca
     3421 gtgcctctcc tccacacaag actttcactc cgcgtccacc cttccacccg aactgcaaaa
     3481 tcattcgcca ggtggcaggg gtcgcttgca gcatggtcac cgcgccatga tcgagctccc
     3541 gttgcaacca ggccccgtcc atcgcctgct gccgattggc cagtatgatt gtggcgccca
     3601 ccaggagcgg aaggtagagt tccagccccg cgatatcgaa cgacagcggg gtcagtgcga
     3661 ccaggacatc gcgatgagtg atccccggtt cctgctgcat ggaacggaga aaattcacca
     3721 gtgcgcgatg ctcaatttcg acccccttcg gctggccggt ggacccggag gtgaacaaca
     3781 cgtacacgag atgctccgga ccggatcgcg gcgacggatt ctcctccgct tgacgcgcca
     3841 ggacctccgc ctcctgatcc agacacagca caggaagctg atgctgcggc agcccgccga
     3901 gcaaggcgga ctcagtgatc aggactgccg cgtgactggc ctcgatcatc gccgccagcc
     3961 ttcgtatcgg caaccccgga accaaaggca ggtaggcacc ccctgctttc atcacggcca
     4021 ggagactgat cagcagatcc ggcgagcgct ccaggaaaac ggggacgacc gcatccggcc
     4081 ctacgccaca ctcacgcaaa cgatgcgcca accggttggc gcgacgattc agttccgcat
     4141 aggaccattc ccgcccttca aagcgaacgg ccacggcatc cggcgtccgg ctgacctgcg
     4201 cctcgaacag ttgataaaaa cacaggccct gatctaccgg tcgatccgtg gcattccatt
     4261 cgcgcaagat tcgatgctgc tcctgcccgg tgagaatcga cacgcgcccg agttctgcat
     4321 cggcatgctc ggcaaccgtt tccatcagct gccggtattg cgaaatccac cgctcggcgg
     4381 aggcgcgatc gaacagatcc gtattgaatt ctaaataggc ttttcgcgac gcgtagggat
     4441 cgatagaaag gccgagatca agttgagccg cgccacggct cacttcatag ggagtccagg
     4501 agagttgatg aaactcggtg cgggcaaagg gcgtattggc aaagttgaac aacacttgga
     4561 cgagcggcaa gcctccctga ctacggtccg gccgcaattc ttccacgagc ttctcaaaag
     4621 gaatgtcctg gtgcgcatag gcgtcgagcg acaggtcccg cacctttcgc agcaggtcac
     4681 gaaacgtcag ctcacctgtc acgtccgctc gcaacaccag cgtattgacg aaggttccga
     4741 tcagctcctc gatctcgaga cggttacggt tagcgatcgg ggtgccaatg accaggtcct
     4801 tctgttgtgt gaggcggtgg aggagcccga agaatccggc caggaatacc atgtacaggg
     4861 taacgccttc gcgcacactc agctgcttga gacgattgat cagcgaccag gacaagtcga
     4921 gcgacacatg atcgcctttg aaggaatgca ccggcaagcg cggccggtct gtcggcaagg
     4981 tcaggacagg cagatcgaca agtttggtct tccaatgcgc gagttgttct tccagcacag
     5041 gaccggtgag ccatccccgt tgccactgcg cgaagtccgc atactgaata gcgagatccg
     5101 gttgaacggc aaacggtctg cccgcgcaga aggcattgta ggacgtgacg agttcccgcg
     5161 cgatgattcc ataagaccat tgatcggaga tgatgtgatg cgtattgagg atcacgatct
     5221 gatcttcatc accaagctgg atcagaaaca cgcgcagaag cggtccctgt tcgagatcaa
     5281 acggtcgtcg cgcctccgcg gtcgcaagtt ccagagcccg tggttcgcgc agctcagccg
     5341 gcactccgcg cagatcctcc tccgtccaag tcgggtccaa tacgtcctga atgatttgac
     5401 gtggctgacc gtccacgtgc gcaaaggtgg tcctgagcgc gtcatggcgc cggaccagtt
     5461 cagcaaccgc ccatcgcaag gccggcttgt tgagcggacc atgcaaccgg acgctggccg
     5521 ggatgttata ggccacggca tccggcgaga gtcgatagag gaaccacatc cgctcctgcg
     5581 cgaacgacag cggaagcggg attcctcttc tggctcgcgt gatcacgtac ccactctccc
     5641 cctgatggga attggctccg gcctgtgcct gtgtgatgac ctcggccaag gtggcaatcg
     5701 tcggacgttc gaaaatctgc cggagcggga gcgtgatgcg gaacagagat tggactctgg
     5761 ataccagttg tgtggcgagg agcgaatgcc cacccagttc aaagaagtga tcatgcacgc
     5821 cgacgtcttt gagctgaaga atctcccccc agatatcggc caggacctgt tccgtgggag
     5881 tacgtggcgc caggtactga gaggtcagct cgaccttgct ggcgcgactg tccgcggcaa
     5941 cttgcagcgc ctttcgatcc accttgccgt tcaccgtcag cggaagcgtt tccatctcga
     6001 tgaaggtcga gggaatcatg tgcgctggca attggctgcg aagctgttcg cgcaactgca
     6061 ccaatccaag ccggttgttc ggacgtggca ccatgaacgc cacgatccgc ttgtctcctg
     6121 gctggtcctc ccgtacctcg accaccgccc gttccagatc ctgatgccgg ttcaggacgg
     6181 cctcgatttc ttccaactcg atgcgatagc cgcgaatctt gacctggcga tcggctcggc
     6241 cccgataatc caattgcccg tcgggtcgcc atcgcaccag gtcgcctgta cgatacagtc
     6301 gggctcccgg ctgcttggaa aatggatcgg gaacgaattg agtctccgta agatccggcc
     6361 tgccccgata gccgcgcgcg actccgacgc caccgatgta gagctccccc gccacaccca
     6421 ctggaaccgg ctgttgattc cgatccaata cgaagacgga cgtatgcgga atggggcgac
     6481 cgatgggcag atcgccgatc aattcatcat gcgcctccag accagtcaga tccgaccaag
     6541 tgaccgcaac ggtcgtttct gttggcccat aggtattgat caatcggacg gtcgccccga
     6601 tcaagtccgt ccagcgctgc acgatctgcg gcagcactcg ctcgccaccg atgatcaccg
     6661 atctgataga ggaaggaaac gcgacctgct cgagcgccat ccgggtaacc agctcatgcc
     6721 agtaggccgt gggcagatcc aggatcgtca ggttcaagtc acggcagcga tccagaaagc
     6781 cggataccga atcgaccatc gtcgcggtac gcagcactaa tgtcgccccc gcggccagac
     6841 agggaaaaat ctcttcggcg gcggtatcga aactcaacga ggcaaattgt agtactcgat
     6901 cttctcctgt caggtcgacg atcttcgtga tggctcgcac atagttggcg atcgagcgat
     6961 gctcgatcat cacccctttc ggatgacccg tggaccccga cgtgtagatc acataggcca
     7021 gattgtccaa cgcatcggtc acgtcgatag ggctgtcggg acacttcgca atctgcgccc
     7081 attccgaatc gagacagatc gtatgcggat tcgtggcggg cagccgcacg agttgatcct
     7141 gttgtgtcac caacacccgc acctgactgt cccgcaacat gtattccagc cgttcggtcg
     7201 gataatcggc atccaacggg aggtaagcgc cgcccgcctt cagaatgccg agcagcccca
     7261 caatcatgtt gagcgagcgc tcgagacaga ggccaacgac gacaccgggt tcaacgccgc
     7321 ggcggcggag ataatgagcg acccggtttg cgcgcgtatc caactcccca taggtcagcg
     7381 actgcccccc ctgttcgacc gctacggcct caggggttct tctggcttgc ttttcgatca
     7441 tacggtggag gcacaactca gggtccgccg tgccggaggg ttgtccccat gcaagcaccg
     7501 tttgctgtgt ttccgcttcc gacatgagcg gcaagctcac gattctgtcg gttggatgac
     7561 tgaccagttc ctgcagcaga cgcacgaaat gctcctgcat ccgcgtgatc cgctcctcgc
     7621 caaacagggc atccttgtat tcgacatatc cgctcagccc atccttcgat tctgcgagtt
     7681 caaggcagag atcgaattgg ccgctttgct gtggaatgac ataggcatcc catgcgagga
     7741 atccaacgtt tgaggccgcg cccgtcgata cgcccatccg cagatcgagt tccgccaaca
     7801 gtttgaactg ctgcaagacg aacaacacct gcgccaaggg ggcacgaggt ccctggcgag
     7861 ccgatcgtat gtcggccacc agccgcgcgt acggataatc ctgatgggcc aacgcgtcca
     7921 acagcgtctg ctttgtccgc gccaacagct cacggccggt caactcagac tgcaggctct
     7981 ctcgcaacac caacatgttc acaaagtcac caaccgtccg ggcgaatcga gcccggctac
     8041 ggccgaacac cggcgtgaca atcgccgtgt cttcttgagc ggtgtagcga gtgagcagga
     8101 tctgcagcgc gctcaggcag acggcataca aggtcgtgcc ctcggtccgc gcaaacttct
     8161 tgaggcggcg agtcaggttc tcatcgatgt ggaaggcatg ccaggcatag tggctcggct
     8221 cgaccgttgt ctcaggccgg tcgtacagca tgtcataatt cggcaattca ccggccagct
     8281 tcgctttcca gtattggccc aggcggctcc cctcttcccc ttccaggatc gcccgatgcc
     8341 actcgacgaa ttcccggtat ggtgcgggac ggtcttgagg ttccggcgaa tgctcggatg
     8401 aacatgaccc ggcgacttca cagcgccgct tcaaatcatc gaccaactgc atcattgacc
     8461 agccatccac aacgatatgg tgggcgacca acaacaacca gctctgctgt ccgccatgaa
     8521 aaagagtcgc gcgccacagg gggccctgcg tcaggttgaa ggggacggct gcagccttta
     8581 cactctcgcc ccgtaactgc ggccactccc aagtggagct gtcgatttca ctccaactca
     8641 acggcatccg gtcatggatt cgttgaaccg gtccatcttc ctgcgtttcg aaggtggtgc
     8701 gcagcatggc ctgctggtcg ccgatggctt caagggccgc gcgcaaccgg tctgccttaa
     8761 ggtcggacgg cagaggcaac aacaccgaca cattcgccgc ggcactgtcg ggatccagtt
     8821 gactcaaaaa ccatagggcg gcctggtttt ccgagagtgg aaacaccgtc gcgatagcgg
     8881 gatctgcaat agcagcaacg gactgggctc gcgattcacc ggccagcccc cgttcaatca
     8941 tcgtcgtcag atcggcgggt gtcgcaccgc ccagaagcgc ggacagcgac agcgacagat
     9001 gaaacgattc ttccaggcga tgcagcacat ctgctgccat caacgaatcg agtcccagga
     9061 gatgaatcgg ccgatcaacc gcaatggcct gcggcatgca accgagccga tcagccaata
     9121 gcttctgcac tgtttgcaga atggcgcttg tgcgcgcctc ccctgaaagc cgctgccacg
     9181 cgtccgtgtg aatgggtgcg ggagatgatt gtgccaccgg atgcggcgcc acactggttc
     9241 cgatgatcga caatcgacct gccaggtact gctcacggca ggcgcgccgt tgcaccttcc
     9301 cactggaagt cttcggaagg ctgccggcct tgatgaagac gatggtcgac gcatggaggt
     9361 cgtgctgctc ggacagggct gcacgcatgg ccgcggccaa gtcctcggtc gaacaaggcg
     9421 acgcctggcg ctccacctcc tggaccagca ccacggtctc ttcgccggcc tcctcaacag
     9481 taaacgctgc cgcgcctccc gcccggagcg cgccatggca tgactcgact gttcgctcga
     9541 gatcctgggg ataatggttg cggcctcgaa cgatcagcag atctttgaac cgccccgtca
     9601 cgaagacttc gccatccttc acaaatccga ggtcgccggt acggaggaac ggcccgtctc
     9661 cggtatccgc caggctggcg ccgaacgtgt gtgacgtttc gtcaggcttg ttccaatagc
     9721 cttgtgtcgt gctggcgccg gacagccaga tttcaccgat ctgttgcacc gcgcaacggc
     9781 accgcgtctc aggatgggca atcaccacgc gagtgtcgcc gaccggcatg ccgcatccca
     9841 cgacctttcg aactggcttg tcgtccgcca cagcttcgat gacggcaccc ttttccaacg
     9901 ctgcggcatc cagcgtggtc acggtaggcg ccgctcctct tcgcttgagc gaaatcagca
     9961 acgtgtattc cgccattccg taggcgggaa agaaggcttc gcgctggaat ccggatggcg
    10021 caaacgctgc ggcaaaccgc tggatcgtgt ccggtgcgat aggctccgcc ccgcaactcg
    10081 ccacctgcca ctggctaaga tccaatcctg cccgttcctc tggcgttgtg gcctccacgc
    10141 aacggcgata ggcaaagttt ggcgcgccgc tatgcgtgac cgcatagcgt tgaatagctt
    10201 cgagccatcg caaggggcgt ttgaggaacg tgagcggcga catgagatac gacggacgcc
    10261 cgatccacgc aggttgaatg atgcccttca ccaatccgta atcatgaaaa tggggcatcc
    10321 aggacagagt cacggatccg gcatcgtaac cacccgcatc ggtaatacac cggctctgcg
    10381 cggtcatatt cccatggctg accatcaccc ctttcggtgc cgaggtcgag ccggacgtat
    10441 attgcaaata tgcgaggtgt gtgggcagtt gctgtaggtc agtccaaccg gaagaatctg
    10501 ctgagagcgc ctggtcgctc gaaacccact ggtgtaacga cgcgacaagc tcctgcgacc
    10561 tgagtgtctc cagcatctga gctgtggtca acgctcccgc ggcgccggca tcttcagcga
    10621 ggcgttgaac gcgcgccacg ccggccttca ggcggaacgc atccggagga ggaaccggca
    10681 cagcgatgag gccggcatag agaacgcccc aaaaggcttg tacgaattca agccccggcg
    10741 gatataccag gaggagtcgg tcccctggcg cgaatcgggc ctgaaggtag ctggcgatcg
    10801 aacgagcgcg cgtcagcagg tctcgatacg tcagtacgct gtcagcgctc agtccttcac
    10861 ggagatagac gtaggccgtc tggtcaggct gatgctcagc ccgccaacgc agcacatcga
    10921 gaagggtgtc gccggctgga atggtgaccg gtggatgtct gaccacagaa tgctcaaccc
    10981 cagtgggatc aggaggcgtt cgcgggacgc cgccgtagac ttattcggac gacggctcga
    11041 aaatcctaag tctgacggca ttttccgtcc ggctttcccg tacgaggtga gtctacggcc
    11101 tcgtggtgac atcgcataat ggattcacgt ttcccttcaa tccatagttc cccctactgg
    11161 tgaaagaaat tccgcccaac ctcatgattt ttcgttgaat cctgggattc gtcagggtaa
    11221 gctgcatgac cttgtcggcc aaggaacgga gaggtgcgag agcggccgaa tcggacggtc
    11281 tcgaaaaccg ttgtcctgaa agggaccgtg ggttcgaatc ccaccctctc cgccattccc
    11341 gatccaacac cccgattttt gcctgtggga gtcgaaccag cccctccctg gaacttgccc
    11401 ttatgtttcg ctgaattgtc aggcatctct cttcgaatcg ccgcacgaag agccgctgca
    11461 cctaccgaag atcgtgccgt ccccttcctc tagtggtcta ttcgcctcca ccgggccagg
    11521 gtagtctctg gtccacacag gagggccaca tgtttgaaca aaccgatgcc gcactggtga
    11581 tgacgctgtt ggccttgggc ggaattgcac tgatggcgga tgaaaaactg ggtacaacct
    11641 gtctgcagat ggtgagatgg attcgcacgc ggggcaggca ctaaccggct cgtcgcttca
    11701 gttccctccg taactcgacc atggccaggg tatcgcgttc acagtatcgt aagagtgcct
    11761 cctgaatctg ggccttctca atccagtcag tcacggtaaa aatcatgcgg ctgtattcac
    11821 aagccgcgac acccccatcc cgaatcacca gatcggcata actcagggac ggcatgacgg
    11881 cgggtaatac ggctttgatg gagtagctgc cttcaaaggc aggatgataa tagtgatccc
    11941 ggatgatcac gtggagatcc cacagcctcg ccactacccg cttgagatcc ttccgtaacg
    12001 acgggaaatc ctccgccagc cgctcaagta ccgatcgttc atagctcgaa tagacgcaga
    12061 tgctgcccgt ctggccgagt gattccaata acgtgatggc caactcttcc ctgggatccc
    12121 gttcatcccg gcacagaaac tcggcatgcg tgagcgtgcc gtcgtactgc tcaatgtgat
    12181 tggaccactg agtgggaata acctggtagg gtctggtatc cacgaatttt ggcaccgccg
    12241 gcatgaaggt ctcaaaatcc agatggtgga cgggatagac gatcgtctcc aacgccgacc
    12301 gcagcccttc gccgatccat tcccggttat ctttcacccg ccgttgcacc ggcgtgagtg
    12361 cgacatgatc aggaatctcg tcgatcgtct caacgcccaa ttcacgaagc tgcacgaccg
    12421 tcttgctact tcccggtaaa tgatagatcc aacgagccgg tttgtgttcg atgcaatggg
    12481 tccagaaggg acactcatag gggctttgac aatgttcatc tggcatcacg gccggagccg
    12541 acatgccttc caacatggcc tgcatggcag cgagtcgcgc cggcacttcc ggtaatcgcg
    12601 gacgcacggt ctccgtcagt gaacgaaggc cgaagagctg gtcgagatcg agataccgcc
    12661 cgtcaaagac gtactgcgta ttcacatgca tcaggcagat ttccgccagc accagtccaa
    12721 gtccttccag gacatagctt tggatcgtca gatcatccac gtgcgtcgcc ttcaccttgg
    12781 tggaagactt cacctccacg agccgccagg tcggttgccc cagctcattc accccgacac
    12841 gttgcaggac atccacacgg acgagaacct ggttgaactg aaaggcccct tcgaagatcg
    12901 ccggaaccgt cggatcctgt agcagctcag ccgtttgcgc cagggcttcc tgagattgac
    12961 gatacccggc cgtgactaga cggccgccgg ggaaacgttg acgcgccagt tcacccagat
    13021 ccgtgcccat atccagaatc gcctgcgtgg cggcatccgg tttggtcgcc aaccccggag
    13081 catgcacctc gaggtacaga cgcttatgac attgcagacc cgatagataa cgcgatttgg
    13141 ataaacgata ggaggagcgc gcggcaggct caggtaagat cagcatagtc tgtgtgcagg
    13201 ctaccgaagc atgacgtgag ttgtccagtc ccgcccagcc ggcgagaaac tccacgaagc
    13261 gagcccggtt ctgttaggat gatgccgcat ggcacagggc atcgcacaga tcagacgctc
    13321 ggttctcacg ctcgcactgc ccgtcaccgt cagtagcctg ttgcaacggg ctgaaggcat
    13381 cgtcgccgtc tttctcgttg gaggattggg ggccgtcccg atcgccgccg tcggcctcgg
    13441 tcaattgctg gcctttatcg ctacgaccct ggtttccggt ctttcggtgg gatccaatgt
    13501 ggtcatggcg caattgtggg gcgcccgccg ttacgacgat gcaggccatg ccgcgcgtca
    13561 tttcctcgga ctctccatcc tcattgcgct cggtctcttg agcttcggcc ttctggtcaa
    13621 tcggctggcc atggaaatgc tcggggcgca agcggacgtg atccgcctcg cgctccccta
    13681 ctcgaacctg atcttcctgc tcattccgtt cacgatcctg ctgcaggtcc tctcttcgat
    13741 cttgcagggc acgggcgaca cgaaaacgcc gatgtacgcc atgatcgtgg tgaatctgct
    13801 ccacattgcc atcgcgattc ccctgatcta tggtcactgg ggcctgccgg ccttgggcat
    13861 caatggcgca gccattgcgg tcggcatcgc ggaagcgacc ggatgtttgt acctcttcac
    13921 acgctgtcgg cctatgctcc gcggctccca ccgattccga ttcgatttga ttcgcacgat
    13981 ctggcacgtg ggggcaccgg tctcgggtga gcgcgtcgtc cagcaagccg gcattttgct
    14041 atacaccaag attgtgttga tgtacggcac cgtcgcctac gcagcccacc aggtcggctt
    14101 gtcgatcgag tccctgtcgt ttcttccggg atatggcttt gcgatcgcag cagccacgat
    14161 ggtgggacag agcatcggcg ccggcaaata cactcgggcg aagctcgaaa cctgggaagc
    14221 aaaccggctg gccgcctaca tgatgtcggc catgggagtg gtgtttttct tgttccccta
    14281 cgcgttgctc cgcgccttca ccagtgatga ggccgtcgtc gaattgggca ccctgtttct
    14341 gaaaatcgtg gccctcctgc agattccgct cgcactcacc atggtggtgg ccggctctct
    14401 gcggggagcg ggtgataccc ggttcgtcat gatcgcgacg atgattggca tgtggggcgt
    14461 acggattccc ctggccatcg tggcgggcta ctggctttcc atgggagtgt tgtacgtatg
    14521 gctggcgatg atcgccgact ggacggtacg catggcattg atgctctggc gacaccgttc
    14581 ggagcggtgg agaagcattc aagtgctccg gtcctctccc acttgaggta ttcagctctg
    14641 gccgtccact gcacattccg gcggacgcac ggccggccgc gtatccttcc ccgatccggc
    14701 tcgtacttcg atgcggccca cggccttcac attggcgcag agatcgccca gaccaggcgt
    14761 caccaaacga taggggccac ctttgccgtc cggaagaggc tgcccatcca gctcgtacaa
    14821 caacagcccg aagtcctgcg cctgctgtag cgtgagggtc gcggcatact tgccatcgac
    14881 ggagtgaaac gtcacatggt ccgcgtccac cgcaagcgcc ggaacctcca gcaggccctt
    14941 cacgcggatg gcgcgacccc gcatggacgg catcaactca ctgatatcgt ccacccgttg
    15001 ctcccgcggc aattgcccca gcgctgttct cgtcaatgag accggctgaa cgaccgcgcc
    15061 gtcgatgcgc acaatgctcg gccctgacag ttccttttca gtgatcgtct tgaccatcgc
    15121 cgtcagcgct tcattcaccg gtgtgggaat acccaactcg cgtcccaccc gcacgatgta
    15181 gccattcaga tagtcgatct ccgtcgggcg tttggctttc caatcgtcgt acatcgacgt
    15241 atggatgtca cgcagctcct gcgtccactt caccaccttc tcggccatgt caggcgccag
    15301 cggaaccttc accgccgcgg acaccgcggc cacttcgccg acaatctgcc ggatgacgcc
    15361 ggccatttcc ggatgatcga gtgccttcgc caccttgtcg tcgatcatga ccgtgagagg
    15421 attgaagaca caattccagc acatcttctc ccatttgctt ttccggatat cttcgctcag
    15481 ttggcaggaa atccctgcct gcttgaaaat gtcggcgatc tgggacacac gctcgctctt
    15541 gtggcccatc agttccccga tcgccacccc gccgcgcttg taatgctcaa tgacgcctgg
    15601 ttcgacaatt ttcgaataga tgaaggccac cccgccgacc acgcagtccc gatgcaggcg
    15661 ggatatgatg cgatcttctg tatcgatgcc gttctgcagg gtgagaatca ccgtgcgatc
    15721 cgtcagcacc ggttccaact gcgtcatgac ctcgtcgagg tcgtaggcct tcacggccag
    15781 gatgatgaga tcaggtgtcg caagctcccg gggatccgag gcggccggcg gatggacggt
    15841 gaaatttccc ttggcgctct tgatcgtgag gccgttccgc ttcaccgcct ccaacgtgcg
    15901 aggccgaaga agaaatgaca cgttgggatt gttcttggcg agatgcgccc cgaagaatcc
    15961 accgacggaa ccagcaccga ccaccatgat ctgcttcatc agctgcctca ctcgttgcgt
    16021 tcaaaagacg cgtactatag catgcagccg cgcacctgaa acagtgaggg gagactgacc
    16081 tttatggaaa ccggatccac tctcggcctt gtccgccaca aactctccac ggcgcggtct
    16141 gtcacaatcc tgaccggagc cgggatctcc gccgacagcg gcgtcccgac atttcgcggc
    16201 gccgacgggc tctggcgaca ctatcgcgca gaggatctcg ccacaccgga agccttcgcg
    16261 cgtgacccgc gcctggtgtg ggaatggtac aactggcgcc gggaactcat cgccaccaaa
    16321 cgaccgaatc cggcacacga agcggtggcg tcgatggagc agcgcttcaa gcagttctgg
    16381 ctcatcacgc agaatgtaga cgggctgcac ggtgacgccg gctcgcggca gttatccgaa
    16441 attcacggta acctctggaa ggtccgctgc acccgatgcc gggacattgt cgaaaatcgg
    16501 ggcgtaccca tcgccatgct gcccctctgc cggtcttgcg gcggactgct tcgcccgcac
    16561 atcgtctggt tcggggaatc cctggcggaa gaggatctgg acaggagtgc cgccgcccta
    16621 cagagcagcg atgtctgctt gatcgtcggt acgtccggga tggtctatcc ggcggcggga
    16681 ttcggcgcca tcgccaagca ggcgggcgcg tttatcgtgg agatcaatct cgacgcgacg
    16741 ccgcactcga atctggccga cgccacgttg caggggcgtg cgcgagatat cgtgccattg
    16801 ttactggagg cgtgacaaga gcggcaggag ttcgttcaac gttgcgatcg tcgcaccgtt
    16861 cgatccctct ggcggcagcc ctctcgccag caataccccc gtcagtccga ccgcgattgc
    16921 gcccttcaca tcatcacgcg cgctatcgcc gacatgcagc gcgtcctccg ggtcgacggc
    16981 atgtttctcc aatgcctgct cgaaaattcg cgcggacggc ttcgcggcgt gagcgaggct
    17041 ggatatcgtg accgtatcga agaagtcggc aatcccgagc ccgcgcagca cggaaaacag
    17101 ccgcgagtca aaattcgaaa tgatccccaa ctcgtatccg tgatccttga gggtcttgag
    17161 cacatccagc gtctccggaa acagcttcca ggactccgct tgcgcaaaac gtgcaaacac
    17221 atcctcaaaa aactcatcaa acttctcgaa catgccgacg cgataaaaga cgttgtggac
    17281 gatatcgaac caccacaggc gctccgattg tttaatcccg cccggttccg tcgcggcaaa
    17341 taccggcggc ggcgcatcgc gaaacgagcg ggcaaacgcc gccttgattg ccgctaacga
    17401 gtcaggcgtt ttgcgaaagc cgtggcgctc cgcatgctgg agataaattt ccgccacgga
    17461 tccttgaata tgaaagaggg tatcggcagc gtcgaaaaac acgacttgga tgcggctctg
    17521 actcatcgta tggattcact cctctctctt cggcactcac ggagcacccg ccaaccggca
    17581 cggtgggcgg attgtatcag gatgcgtaaa acctccgcca gcgctgagcg cccgaggccc
    17641 acccctgcct cgtcagaaca gttggattcg gcgttttctt tgacagtttt cagacccttt
    17701 gttagcttcg ctggagtggg tagagcgagg tgtttccaat gggttccacg atcttcgtca
    17761 tcgacaacag tccggccgtg cagcgcatgg tggagcaact ctccgccccc gatgggcatc
    17821 gggtattggc gtttcaagac ggcccctccg cccttgaagc cgcccgatca caatgccccg
    17881 cgctgatcat tgccgattac catctcgagc agatgacttt ttccggattc tgcaaagaaa
    17941 tcggacgaca ggacaatctg gccgaaacgc tcatcgtctc aatcgtcgat agtgccgatc
    18001 gtctcgatga aagcaagctg cgcgcgcttg gcgtgcgggc gtttctcaaa aagcctttcc
    18061 aacgcgaaca actcctcgag acgattcaga gcattctcag caaaccggaa ggatcccgca
    18121 gccagaaacc agccaagtct cgcacctggc ctccggccac cacgggagcg gacgacgatg
    18181 acgagacctc gccggatgcc tctgctgaac atacgtcccg cctggcggag aagaaggagc
    18241 agccccccat gtcgtcaaca gcacccgcaa ccagacccac gggcgaggac ttgatgaagg
    18301 ggctggtcga acatctcctc cactcaacga ccgtcaaagc cgaccgggcc atcaccgagt
    18361 tgttgcccgc cgccgttgcc aaggaggttg cgggccaatt aggggccgcg ctcagcaagg
    18421 ccgtgcaggc cgaagtgagc aaacaggttg cggaagcgct cgccccggaa cggatccaga
    18481 acaccctccg cgaaatggtg cagatggaat tgaaacgtca gagcgagtcg caacgtgccg
    18541 gcatggagtc cagcatccga caagcagtga cggaattggc tcctggcctc atggcgcagt
    18601 cttcggaaaa attacttcca gggctcacgg acgctggcgt gaagcaacat ctgccggaag
    18661 ccttgcagag ccaacgcgac ctgatcacgg atggagtgaa aaaagaagtc gagcaggtgg
    18721 ccgcgaccta tgcacgccaa gcggccgagg acattgtgcg ggaattggcg aaagacccga
    18781 tcctgcaggc ggtgcaacgg gtcgttcctg acgtggcgga aactcagatc cgggccgaga
    18841 tcacacgatt gagctcaccc gactaacacc tcgacgcgtt accctcgctt cacctttttg
    18901 gccgctgcac ggcgggtctt agccagcgcc ttcacgcgcg cgacattctt ccggtgtttc
    18961 ttccgaactt tccgatcctt ctcacgtccc ctcggcatag tctctccttc aacggtaaaa
    19021 tcggcatgct ggccggcgag cgcactcgcc atcgactgaa ccgccggatg tatatcacag
    19081 ggcttcactc cgctacaacc ttttgcaccg ccacagatgc accgtcgtta ccttgagcgc
    19141 acaagcagca catgataaga tgcgcccgcg ccgcagtgtg cgcctcttat gtccacccca
    19201 caactcgata aaacctacaa tccacacgac gtcgaaaacc gctggtacca gcgctggatc
    19261 gatgccggac tgtttcatgc cgatccggcc cagaccgggc aaccctactc catggtgatc
    19321 cctccgccga atgtcacggg atcgctgcat gtgggtcatg ccctgaacaa caccctgcaa
    19381 gacatcctga tccgctggcg ccgcatgcaa ggtcgcaacg tgctgtggat gcccggaacg
    19441 gatcatgccg gaattgcgac gcagaatgtc gtggagcggc aactgcaagc cgaaggcacc
    19501 tcacgggaag cactgggtcg agaggcattt ctctcgcgcg tgtggcagtg gaaggaaaaa
    19561 tccggcggga cgatcatcgg ccagctcaag aaactcggag cctcctgcga ttggcagcgt
    19621 gagcgcttca ccatggacga agggctctcc gaagcggtcc gcgaagtctt cgttcgcttg
    19681 catcaggatg gcctcctcta ccgcggtgag cggttaatta actggtgccc gcgatgtctg
    19741 accgctctgt ccgacatcga agtcgaacac gaagaagcga ccggaaaact gtacacgatc
    19801 cgctatcacc tggtagatga tccgacacag tttctccttg tggcgaccac gcgccctgaa
    19861 accctgttcg gcgacacggc ggtggctgtg cacccggaag acgaccgttt ccgccacttg
    19921 atcggcaagc acgtccgttt accattgacg agccgtgcaa tccccatcgt gggcgattcg
    19981 atcctggtcg atcgggaatt cggcaccggc gccgtcaaga tcacgcctgc ccacgacttc
    20041 aacgattttg aggcgggaga gcgacacgga ctgaaacgga tcaagatcct cgatctccac
    20101 gcccaccttc gattgggcgg ctctttggcc gatcccgccg tcgcagaggc agtcgagaat
    20161 cttcctgtcg cgaaggctcg cccgaagatc gaacaattcc tcaccgatca gggatttctg
    20221 gaaaaatccg agccccacaa gatggcactc ggcaaatgtt atcgctgcaa gacggtggtt
    20281 gaaccgttct tgtcagacca atggttcgtc aagatcaagc cgctggccga accggcgatt
    20341 caggtcgtcg aagacggtcg cgtccgaatt atccctgaag cctggaaaaa caactatctg
    20401 ggctggatgc gggacatcaa ggactggtgc gtctcgcggc agatctggtg gggccatcag
    20461 atccccgcct ggtattgcga aacctgttcc ggcactccgt ttttacggcg aagttccgat
    20521 ggcgccccgc tcataccgtc ggatgcagcg gcgatcgtgg cgaagaccaa accggactcc
    20581 tgtccgctgg gccaccgcga cgcgctcgtg caagatcccg atgtcctgga cacctggttc
    20641 tcctctgccc tctggccgtt ttcgacgctg ggatggccca agcagacgcc cgaattgaaa
    20701 gccttctatc cgacctctac cctcgtgacc gggctcgaca ttctgttctt ttgggtcgcc
    20761 cgcatgatca tgatggggtt gaaattcatg ggcgatgtgc cgttccgcga cgtctacatc
    20821 cacgcgctcg tccgcgatgc cgaagggcag aagatgagca agtcgaaggg caacgtcatc
    20881 gatccgctgc atgtgatgga acaatatggc acggatgcgc tgcgctttac cctggcagcc
    20941 atggcctccc ccgggcgcga tgtgaaactg gccgaagaac gtatcgaggg ctatcgcaac
    21001 tttacgaaca aaatctggaa cgccgcacgg tttctgctca tgcacctgga cggcgaacgc
    21061 accgacgtcg cgccggcaca acgatcgttt ccagaccgct ggattctgag tcgcctgaat
    21121 accgccatca gcacggtcac ccaggaattg gagcagtatc ggttcgatcg cgcctccagt
    21181 gcggtctatc aattcatctg gcacgagtac tgcgacaagt acatcgagat ggtgaagcct
    21241 gcgctcaagg atgcgaactc cgaacaggcg aagagtacgc ggcaaacatt ggccgagaca
    21301 tatgaaacca tgatgcgatt gctgcatccg ttcatgccgt tcattaccga agaaatctgg
    21361 cagaccctgc cgcatgaagg aaccagcatc gtccgcaagt ccttcccgac cacgagaaag
    21421 gattgggagt cagaagaagt cgaacaggag ttcgcgctgc tggaagaatg tcgcgccctg
    21481 atgaaccagg agcgggcgat tctcggatac cctgcaggga aacgtctcca cttcaaagtg
    21541 cacggcaaga cagaagcgat tgcatccatc cttcagaaac ataaagacct gatcgaatac
    21601 atggagaacg tagacaatct ctggattgcc aagacgttcg acgtcagcaa tccaggaggt
    21661 cttctgatcc tgacgagcgg ctctatccaa gtgcggacct cgatggaaga tgcggacctt
    21721 ggaaaagccg aagaaaatgt tcagaaacaa atcaagttgc ttcaaaaaga agtcgaccgc
    21781 acgcagcaaa aactgggcaa tcccgatttc gtggccaagg cgccacctga cgtactgacc
    21841 gaacaccgcg agcggcttca gcgcgaatct cacatgattc aactttttca gcaggcgctg
    21901 gaccagatca agctctatac cttggaacga acacgtattg agcaccccta gcccccagac
    21961 gatcctcaac gccgtgcaac aggcgctcgc cgaagatctc taccatggcg acgtcaccac
    22021 cagtgcgttg tttcccaggc cacttcgcgc cactgcgacc atcgtagccc atcaaccaat
    22081 gaccgtggca ggtgtggccg tcgcccggga agtgttcctc gctgtagacc cctcggcccg
    22141 catcaccaaa gccgtcaagg atggcagcgc cgtaaaatcg gggaccacgg tactgacggt
    22201 tcaaggcgat gtgcgctcgc tactgatggc cgaacgcgtt gcggtcaact tcctccagca
    22261 gctgtcaggc atcgccacac tcaccgccca gttttgtgcc gcagtgcgtg gctatccaac
    22321 cagaatcctc gatactcgca agaccacgcc aggattgcgg gccctcgaaa agtgggcggt
    22381 gcagctggga ggcggcaaga atcatcgatt ttctctgggc gacggtgtgc tcatcaagga
    22441 caaccacctc gccgttttgc gctcgaccgg cattgatgtg gcaggagcct gtcgcctcgc
    22501 gcgagccggt gcgcctcatg gccttcgtat cgaggtggaa gccaaaacca tgcaggaagt
    22561 gaaagaagcc ttagcgggca aggccgatat cattctgctc gacaatatgt cgcctgccca
    22621 ggtgcgccag gccgtgacac tcatcaaaca acgcgccttg gtcgaagtgt ctggtggaat
    22681 gaccctgcaa acggtcgccg ccatggccca ggtcggtgca gatttcattt cggtcggcgc
    22741 cttgacccat tccgcgcccg cagccaacct cagcatggat ctctcagcac agcgaggacg
    22801 ccgtgggcgg tcccattagc gattcgccga tttcccctcc tttcgacatt gatcgcctcc
    22861 aagcctccct gcgcacccac gccttcggca gaccgttgcg ctattcagcc tcgaccgcgt
    22921 ccaccaatgc cgatgctctc gcatccctgc aacaatcggc gacacagcca gcccctcatg
    22981 gaatggtcat tcttactgat tgccaaacgg ccggacgagg acgtcgggga cgaacctggc
    23041 attcaccgcc gcagggcaat ctgtatctct cggtcatcgt ggtacctcga cctgtcgcca
    23101 caggcacaac accctggctg acctggattc cgctgttatc cgccctcgcg ggagccgact
    23161 gcctctctca acagacaggg cttccggttt ccgtgaaatg gccgaatgat ctgctcatcc
    23221 acgacaagaa ggtcggcggc atcctgtgcg agcaaaccac tacgccagat cgaacgatgg
    23281 ccatcattat cggcatcggt ctgaacatta atgcgccgct caacaccttt cctgaagatc
    23341 ttcaacaagg tgccaccacc ctggccgcag aagccggcca tgaatttgat cgcgtggcca
    23401 ttctggctga cctgctgttt cgactggaac aacgactgaa tcggctgttt ctcgagggtc
    23461 ccgcggggat gatcgatgaa tttacccaac gctgctcgac cgtgggccaa accgtccggg
    23521 tcaccctcga agaaaagggg atggttcaag gaatcgccga gtccatcggc cctgatggct
    23581 gcctccgcct gcgggtgaca tcgaacgagt ccccgtccct tccctcgaca ttgttagaag
    23641 tccggagcgc cgaggtcgtc catctgcggg ggtgaaatcc tgctacggct tggggtagag
    23701 tgaaggcacg atgctgttgg caatcgacat cggcaacaca aatgtagtct gcggcctgtt
    23761 cgaaggctcg accctgcgcg ggcattggcg catggccacc gaatccagac gtaccgacaa
    23821 tgagtatggc atcctgctgc tgaatctgct ccaaaacgcg ggctttaccc cggaccagat
    23881 caccggctgt gtcctctcca gtgtcgttcc tgcgctcacc gccaccttcg attccgtggt
    23941 gcaggagtat tttcatcgca ccgccgtcat cgtagggcct gagactgact ccggcttgac
    24001 gctgcgctac gcgaacccca aagaaatcgg cagcgaccgt atcgtcaacg ccgccgcggc
    24061 ttatgcgcgc tatcactcgg atgtcattat cgtcgacttc ggtaccgcta cgacgttctg
    24121 cgccgtaacc aaatcggcgg agtacctcgg cggcgttatc gcaccgggtc tcggcatttc
    24181 agccgacgcc ctgtttgccc gcaccgcgaa actgccgaaa gtcgaaatca tcaggcccaa
    24241 aaccgtcatc ggcaaggata cgatcggggg cattcaaagc ggcctcctgt tcggctatgt
    24301 gggactggtc gacggcattg tccgacgcat ggaacgggaa cttggccgca cctctcgagt
    24361 cgtcgccacc ggcggtctgg cgaccgtcat tgcacaggag actgaaacga tccaggaagt
    24421 ccttcccttc ctcaccctcg aaggcttgga actgctgtac cgccggaatc gcctcgctta
    24481 ggcgcctttc cgacgggtgc tgtcacaaca ttccatcccg cgaacgctga gagactcgaa
    24541 aaaacgacta tttcttttca ttccccgttg acttccatcc tccggtggct atctcactca
    24601 ccagaaaagg tgcaatcaat gtctgaagac gagaagaacg ttcacagtat cgacaactta
    24661 gatagttcag acgaaccctc ctctgcgacg attgacggtg caagcgaatt gcagcaggtg
    24721 ctggatgcga aagccgagga gtgcaaagcc gctcacgaaa agtatctgcg actggcagcc
    24781 gaattcgaca attacaagcg gctggcccaa cgcgaccaac gcgagcaaat caaattcggc
    24841 aacgaacaaa ttctgaaaga gcttctcccc gtcgtcgata acttagaacg agccatcaaa
    24901 tccgccaaag gggcgggctc tgtggatgcc ctcacggaag gcgtcgagtt gacactcaag
    24961 caactcgtgg gtgccctatc aaagttcggc gtcaaagcgg tggagagtgt gggccaggtg
    25021 ttcgatccgg ctacccaaca ggcagtcgcg caagtgccgt cggacacgat tcctgaaaat
    25081 cacgttgtgg aagagtatca aaaaggatat ctcctccaag atcgcatcct ccgggcagcc
    25141 atggtcaccg tatcgaccgg ggcggcgaat taagacggta cgtacgcaac ttgtttcgcg
    25201 agcacagctg acacgatcgt tcacgtattg atattttttg cgaaggagcc aacccatggg
    25261 caaagttatt ggaatcgacc tcggcacgac gaactcctgc gtcgccatca tgagcggtgg
    25321 agacc
//
LOCUS       DAOQPD010000055        24532 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_967_length_24532_cov_25.341177, whole genome shotgun sequence.
ACCESSION   DAOQPD010000055 DAOQPD010000000
VERSION     DAOQPD010000055.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 24532)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 24532)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24532
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_967_length_24532_cov_25.341177"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(496..579)
                     /locus_tag="PK063_12710"
     tRNA            complement(496..579)
                     /locus_tag="PK063_12710"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(544..546),aa:Leu,seq:gag)
     gene            807..1502
                     /locus_tag="PK063_12715"
     CDS             807..1502
                     /locus_tag="PK063_12715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HMZ97960.1"
                     /translation="MTPLSAPHISCTGRQTDIAALFDVDNTLLPGQASEVRFFRFLWK
                     RGLVGWREVRDSIHWVLRCAPPVSLHPLRERKLYLAGKGAAEVEALAEEFCRTELCPR
                     LSAQGLSRMDEHRRAGHHIVLVTGSLDFLIAPLAALLEVPTLLAARLEQQEQQFTGHV
                     CAPLPYGPGKRELIARLTRESGIDLAQSFAYGDSPGDVELLEMVGHPLVVNPIRGMDR
                     IAQRNGWPMTTWK"
     gene            1553..2191
                     /gene="queE"
                     /locus_tag="PK063_12720"
     CDS             1553..2191
                     /gene="queE"
                     /locus_tag="PK063_12720"
                     /EC_number="4.3.99.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="HMZ97961.1"
                     /translation="MLRVTEIFHSIQGESTHAGRRCVFIRLTGCPLRCTWCDTAYAFY
                     GGQDLTEEDVVAQVRAFGCNLVEVTGGEPLSQAACLPLLRRLCDEGFEVLLETSGAVD
                     TAGVDERVHVVLDVKCPGSGMVDRMYWPNVDRLTRRDEVKFVIKDRTDYEWARKVVRS
                     RDLEARCTVLMSPVFGEVDARQLAEWVLADRLPVRFQLQMHKQIWAPDMRGV"
     gene            2256..3776
                     /locus_tag="PK063_12725"
     CDS             2256..3776
                     /locus_tag="PK063_12725"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0019538 - protein metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HMZ97962.1"
                     /translation="MKKIQVQAQVGRAEQEGAEVLVLLCCEGASDLSPEAAAINTQLG
                     GQLATLIQRGEFEGKLGEGLLVHTQGKAKAKRLLLAGLGKEKDLRLDAFRQALGAAVK
                     RVRQAKVSSFGVVLPGAVLEEIPVQDVAQAMAEGAILGNYQFTAYRSSNGSKPVEVER
                     LTIYVAQTSLLAQVTEGIRRGVATAEATVLVRDLCNHPANIMTPGRIVQEAKAVAKEP
                     GVKLKVLEQKDMEQLGMGALLGVAKGSHEPPKFIILEYKGAKAKKGDPPVVMVGKTIT
                     FDTGGISLKPAENMEHMKADMTGGAEVLATMRAAARLKLPVHLVSILPVAENMPGGRA
                     MRPGDIVKTLSGKTVEVQNTDAEGRLILSDALAYATRYKPAVLIDIATLTGACVVALG
                     QFAIGMFGNNDQLKEHVRNAGMRAGERVWEMPLWEEYFEQLRSDVADMRNIGGRGGGM
                     ITAALFLSKFVGDCPWIHLDIASTDWSERERAYLPKGPTGIGTRLLIQFLLDRTLP"
     gene            3851..5002
                     /gene="nagZ"
                     /locus_tag="PK063_12730"
     CDS             3851..5002
                     /gene="nagZ"
                     /locus_tag="PK063_12730"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HMZ97963.1"
                     /translation="MTLREHIGQLFMMGFTGTTVSKDLASFLTAYKPGGVIFFRRNLE
                     SVQQIVDLTNGLQKLSPASPLLIAIDQEGGRVSRLPAEFTIFPPCGQLGQCHSSELAY
                     SAAATIAKELRAVGINMNMAPVLDVNSNPDNPVIGDRAFGAEPDVVADMGLATIGGLQ
                     DNMVVACGKHFPGHGDTATDSHKELPVVDAGIQRLRETEFPPFQQAIRQGVASLMTAH
                     VLYRALDPDAPATLSPAVIQRLLREEFRYDGVVFTDDLEMHAIIDHDGIGEAAVRSFV
                     AGCDVLLICKDQDRVMTAMQAMERAVQNGRITQERLEQSLARVARLKARYLIPYKPVT
                     ISDARLVVGCRSHKVLLDSWHKAYARLPSSKVSEHDEPAAALDSPVTHV"
     gene            5153..5542
                     /locus_tag="PK063_12735"
     CDS             5153..5542
                     /locus_tag="PK063_12735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97964.1"
                     /translation="MGIKKGDILDERKRFPDSCGLVVKCTGGGEGFQKIFCCGHELTE
                     EDLVSEIVSSRGRKRGTLLPGAMLEERRQFPDSCGLRLMVMDGGAGLQGIDCCGHLIT
                     AGAVHGLRFGQPLDEGAPMPTGPAGQA"
     gene            5542..6063
                     /locus_tag="PK063_12740"
     CDS             5542..6063
                     /locus_tag="PK063_12740"
                     /inference="COORDINATES: protein motif:HMM:NF017913.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-starvation-inducible PsiE family
                     protein"
                     /protein_id="HMZ97965.1"
                     /translation="MRAPSMPGADEKFHRPSMRWWLGFMDQLDRLGYVAAGFSLLALC
                     LIIFVHAWYIFLARPVQLALLPAALKLLNDLLLVIILLELFRTVVRFLQTEVLELEPY
                     LSVGIIACTRRLLTASAELSYQLEAVAKESRHELFQQYLLDVGLNVLVIIILIGGLYL
                     LRSRPSTERPAVS"
     gene            complement(6476..6643)
                     /locus_tag="PK063_12745"
     CDS             complement(6476..6643)
                     /locus_tag="PK063_12745"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97966.1"
                     /translation="MTPLHEHFDDGETKTTLRLARLGRPWVRLRQGPQQGRPVWQQPL
                     PVQLGQVRQLK"
     gene            complement(6640..8085)
                     /locus_tag="PK063_12750"
     CDS             complement(6640..8085)
                     /locus_tag="PK063_12750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HMZ97967.1"
                     /translation="MGNPLFRTKSIERILADSDAPEHRLKRSLTAWDLTGLGIGAIIG
                     TGIFVLIGTAIVGDAHRPGAGPGIVLSFILSGITCALAALCYAEFAAMIPVAGSAYTY
                     SYATLGEFLAWLTGWNLILEYGVACVAVAIGWSGYFNNILKLCGLELPYWATHPPGAD
                     GGIANIPAAIIVLLVTGILIVGVKESARATCGIVLIKLAVIVFFIAVGTSSVDTTNWT
                     PFMPFGFAGVGAAAAIVFFAYIGFDAVSTTAEEAKNPQRDLPIGIFASLGICTLLYIA
                     VAAVLTGLVPFSRIDIHAPVAEGLRVAGFKWGAAIVAVGAVAGITSVLVVMMLGQIRV
                     FFAMSRDGLLGPWLSGVHPKFRTPHHATYLTGIAVAIMAALIPIGEAADMTNIGTLFA
                     FVLVCIGIIVLRYTNPNHPRPFRMPFMPVIPMLGVLACLGLMYFLPWMTWIRFFVWTV
                     IGIVVYATYGIRRSKLATSPALEHTSHARRA"
     gene            complement(8149..8925)
                     /locus_tag="PK063_12755"
     CDS             complement(8149..8925)
                     /locus_tag="PK063_12755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HMZ97968.1"
                     /translation="MKPVIGVTPDFNAGDRQEWGGKEPTYFLRARYVRAIEELGGVPL
                     ILPLVADRAARRRLLRTIDGLLLTGSGPDLDPALYGERKQYSFPIVAQRRSSFELDLV
                     HLATRNHLPTLAICGGMQTMNVAFGGTLYQDLPAQVPDVLQHRQTTPAIQLAHSVSIT
                     PGTLLERIMKRPRMKVNSSHHQSVKVVGRALIASATAPDGIVEAIEHPGHPFFLGLQW
                     HPEFLFERHRLHRQLFEAFLRAASRRPALRPLSPQRGTTT"
     gene            complement(8927..9403)
                     /locus_tag="PK063_12760"
     CDS             complement(8927..9403)
                     /locus_tag="PK063_12760"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97969.1"
                     /translation="MNVSVNLSSKRRRSLWSNALVLGLVAICSLAILIVPVAAQESGS
                     ASNVPVSSNDASPSGVGIQAGSALATIIYFPLKLAFAIGGGVVGGLAYGFSGGSEQTA
                     KNIWIPSMYGTYIITPDHLKGDKPIRFLGVSSSEPTREAGDYTPQEPLPLPLEPIR"
     gene            complement(9560..10021)
                     /locus_tag="PK063_12765"
     CDS             complement(9560..10021)
                     /locus_tag="PK063_12765"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97970.1"
                     /translation="MSIPPAATEPSQYRVTFFFGPEPVEHRPDLLRCVFNVKKRSWKG
                     GIQVSLDIAMKHVEEARRAIGFSTWVEHQLHKICQEEQAELTRRADELFIQSVCTCAL
                     NLALHGGIEQHNQVIDAARFTDELRQIMTEQPEQVMERIRLELDLEESPDR"
     gene            10113..11330
                     /locus_tag="PK063_12770"
     CDS             10113..11330
                     /locus_tag="PK063_12770"
                     /inference="COORDINATES: protein motif:HMM:NF012766.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro peptidase family protein"
                     /protein_id="HMZ97971.1"
                     /translation="MKTSADFVAQVDRIQEAIRAHPGIDGWLFYDFRHLDPIAYRVLL
                     LDPSMHVTRRWYYWVPAVGMPVKLQHRIEPHVLEALPGEVRFYVSWREQQTALRALLQ
                     SAKRIAMQYSPMNAIPYLSRVDAGTLDLLRSWGLEIVTSADLVQQFEAVWDEAQLASH
                     QAAATGLRAIVDEAFGFIGTSLAAGSSLNEYGLQQYILSRMHARGLVTSSPPIAAVNA
                     HSADPHYGPSAEGSAPVRQGDLVLIDLWAKQPEARAVYADITWTGFVGKVVPARQQDV
                     FQIVRQARDAAVTFVQARVREGTFPYGWEVDDVCRQVIQQAGYGEHFVHRTGHSIGEE
                     VHGNGANIDNLETQDARRLLPGTCFSIEPGIYLPGDFGIRSELDVYLSTNDAVVFGQP
                     VQTELVAITLPTT"
     gene            11465..12319
                     /gene="tatA"
                     /locus_tag="PK063_12775"
     CDS             11465..12319
                     /gene="tatA"
                     /locus_tag="PK063_12775"
                     /inference="COORDINATES: protein motif:HMM:TIGR01411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase TatA/TatE family
                     subunit"
                     /protein_id="HMZ97972.1"
                     /translation="MFGTMGFSELIIILVIVLIIFGAGKLPQIGEGVGKALRGFKKEV
                     NDIPAADATPEQGEAATPSSQAQIPPVAEVAQTAQPAPVAQAAPSLKPTAPYTPGPEL
                     TPGTTAALMAAAAPQGPQTAQASKPRVATVTPTQAAPGSVVAQGHQPPTMEDRMAAPA
                     PVMRGQYPPLPASAQSKPVAKRPSAIVNKDAVARVQAAQAAIRAKAAQPQPAAFSPQD
                     MQGLGEGLGDAVRTFRQAVADVRSSVDPQMRTIRAEMDSAQKELEQSIEAAKQAPVLD
                     EDTPAKPL"
     gene            12634..13320
                     /locus_tag="PK063_12780"
     CDS             12634..13320
                     /locus_tag="PK063_12780"
                     /inference="COORDINATES: protein motif:HMM:NF025030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HMZ97973.1"
                     /translation="MRLNELLADPDPEVRRTAAEGLGKIGHPSASPGLIAALADRDPH
                     VRAAAALALGRVGDAKSGAALVEHLSDSSESVRTASALALGEIGTSVSHEEQILRALR
                     QPEVSTRLAASRALLSLETVSFSTDLLSALDDPNAQVRQGVVAVLSETGDRRPLPSLM
                     RLLQTDEDAGVRAEAAFRLGKVGDAGVVPALSVVAEKDSNPTVRQWAHWAVRQITTSP
                     GFGSGNRQGQ"
     gene            complement(13274..13792)
                     /locus_tag="PK063_12785"
     CDS             complement(13274..13792)
                     /locus_tag="PK063_12785"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ97974.1"
                     /translation="MKFPVTATREHHGKTLGIDCEQETVSLFDHKGQQLSILSWGTLI
                     EHMLSVDEDARFAHSRSHPRAPLAIKVHCTTEDGKHFDSLTGGIGGGGLFIESSTPLA
                     PGTELTVEFALPDRPNQKFATRAKVAWTRSKPERYLLFPGMGIQFTDIDPVAQTRLID
                     LVDSLNRSRAMS"
     gene            complement(13869..14387)
                     /locus_tag="PK063_12790"
     CDS             complement(13869..14387)
                     /locus_tag="PK063_12790"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ97975.1"
                     /translation="MKFPVVSSTRHKGKTIEIDSSKESITLLGINGEPMGSLAWDFLV
                     DQILTYRKPQQSREARSEPRISLSIRVKYHTPDGMQFESRAGGIGGGGLFIESLAPLA
                     VGTKLAMEFTLPEDPSEWMSAKGVIAWVCPKADQYTFSPGMGVRFTDIASETRSRVLN
                     LVHSVKGIPQSE"
     gene            complement(14598..15854)
                     /gene="clpX"
                     /locus_tag="PK063_12795"
     CDS             complement(14598..15854)
                     /gene="clpX"
                     /locus_tag="PK063_12795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HMZ97976.1"
                     /translation="MAKQEKIDRHLRCSFCGKSRDEVRKLIAGPTVYICDECVNLCND
                     IIAEDWEEAKEEISSKLKKPAEIKHHLDQYVVGQDRAKRILSVAVHNHYKRISAKDKD
                     VDDVELQKGNILVVGPTGTGKTLLAQTLAKFLDVPFTLADATTLTEAGYVGEDVENII
                     LKLLQAADYDVERAERGIVYIDEIDKISRKSDSPSITRDVSGEGVQQALLKLIEGTVA
                     NVPPQGGRKHPHQEFIQVNTSNILFICGGAFVGLEHIIEQRLNRKSMGFGAEVRGRND
                     IRLGELLPHVQPEDLLKYGLIPEFIGRLPVVATLDELDEQALIRILTEPRNALTKQYE
                     KLLSFEKVKLRFTEGALSAVARKAFTQKTGARGLRAILEEAMLDVMYDAPSQKQIKEV
                     VITEDAISGKHAPIRIFEQDKDVKSA"
     gene            complement(15881..16516)
                     /gene="clpP"
                     /locus_tag="PK063_12800"
     CDS             complement(15881..16516)
                     /gene="clpP"
                     /locus_tag="PK063_12800"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HMZ97977.1"
                     /translation="MLVPIVVEQTNRGERAYDIYSRLLKDRIIFLGAPIDDVFANLII
                     AQLLFLEAEDPEKDINLYINSPGGSVTAGLGIYDTMQYVKPSINTICLGQAASMGAFL
                     LTAGTKGKRYALPNARVMIHQPMGGFQGQATEIDIHAREILKIRERLNEIMAKHTGQP
                     LDKISQDTERDYFMSSEEAKRYGLIDEVITRPLKSLKPVGSTDSGKDGGKS"
     gene            complement(16641..17966)
                     /gene="tig"
                     /locus_tag="PK063_12805"
     CDS             complement(16641..17966)
                     /gene="tig"
                     /locus_tag="PK063_12805"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: protein motif:HMM:TIGR00115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HMZ97978.1"
                     /translation="MKMEMTELGPMKRALKIEVPADEVNLRFVQAYSELNRQVRIPGF
                     RPGKAPLQLLEKRYAKTIEEDVIRSLVPDYYDRAIRQAGIVPVLVEIPPLERVKVKKD
                     SPFSFTATVEIKPTIELRDYKAPNPISLKQDQRTVTDEQVQKALEVLREQMAQLHPAP
                     AGTTLADGDYAVVDIDGTVDGAALDGTTKTGHLHKMGSQSSVLGIEIEPHLLGKKEGD
                     VITIPQAYPATHPDARVAGKTVNFRCTVKSIKRKQLPALDDEFAKDCGPYQSLQEIRE
                     KLHAEMDRALKKDIEDSYKDTILKRLAETHHFDLPGTLVERELSAMVRQQLQSRQRKT
                     GDAADGSPGASQADEAKQLQEEYRPEAERRVKVGLILEALATKENITVTNEDLSNEIA
                     RLAAEVKLSVEEVTRMIQAGGQDTLNDLRSRILADKALDFVYKHAMIQG"
     gene            complement(18027..18109)
                     /locus_tag="PK063_12810"
     tRNA            complement(18027..18109)
                     /locus_tag="PK063_12810"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18073..18075),aa:Leu,seq:tag)
     gene            18442..19527
                     /locus_tag="PK063_12815"
     CDS             18442..19527
                     /locus_tag="PK063_12815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HMZ97979.1"
                     /translation="MKRQSVTAALGCLILLCGFPLSSEAYRDYFTDAQKQELVKIQTV
                     LIEALALTDKGAGNADGILDVAMKRMGELGYTTVSDPHVSHDVVVRVKCEQKKTWEGT
                     ASAGGDNDLPDAPSRLWKGPACQITYALGGMKVKWQKEVRTEFEDAVGAAQSAQAPDP
                     GLYAMNALHDALETYEFPLLLTAEWGQPDRLLKLLDSPQTSQIRKLKIISLLGEMVAD
                     EALPHLTEALKDKDLAKQAAVALGNMGKEGIPVLIDILKHSKQPELQAAAAKGLGDLG
                     NIHSDSRVVTPLLEMLDAPGIDIVVQTEVAWALGRVPDRRSVEPLFALDRKLQKIRKD
                     PPDPQIKKLKEAVFWSIKQVYTEDQYS"
     gene            19801..21042
                     /locus_tag="PK063_12820"
     CDS             19801..21042
                     /locus_tag="PK063_12820"
                     /inference="COORDINATES: protein motif:HMM:NF024850.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HMZ97980.1"
                     /translation="MRDISRRRFLQISAMSGGVLLLGDLAERILNVPLLRSAALAAEP
                     IKIGILDPLSSPYKTSSIHDVHGANVAVDLFNKRGGVLGRPVMIMEADDASNPDTALK
                     AATKFVQDDRVDVLMGTFNAECALVVSEYAKKANKLFMVTGAHLPELTGAACNSHTFV
                     FMPNASMLAQAVVPQLVKAYGTRWYMITTSSLDGKAMAQAMASTGLTHGVEFVGETLM
                     PFGSTDFTSALSAAKDKRPTLVVLNLYGWDLVHALKAYTKLELAKDKIGVGGMIAGEQ
                     IGRPLGYANNAGIWGLIWDPKVNTDGSKRFIQGVVEKYNHTPTSRCYLGYAAMTQILE
                     AIQRAGTTEASALIKVLEGHEFDGLKEGRSYFRASDHQHVQDVLVGEAYGKELGLGHY
                     KILATVAGESVATVQSGSCQL"
     gene            complement(21064..22515)
                     /locus_tag="PK063_12825"
     CDS             complement(21064..22515)
                     /locus_tag="PK063_12825"
                     /inference="COORDINATES: protein motif:HMM:NF012894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HMZ97981.1"
                     /translation="MRRAVWALMVLGALASACETVPQPQPVAAPPQVGDAKLLALQQE
                     REQLLTTLGEFHDRIRDLESKLGDRQNQPAAASYDQLLNAKDAELAELRRLSPERDKL
                     TSQLAMANNELLQARQRIGSLEQQLATREKDLVALQGRSTAISDLEVARRRIMDLEAQ
                     VARQDHDLRTIKSENAERDSLAAQLQTATATIDSLKARISALDQQLRDREQAFETVRS
                     RLMERDKLVPQYNAMIAEIYQARHRIAALEQRLNEKSRDLSPRQKGAQAATAPRETGA
                     TSNKNAGSSEKDAGRTGSATPTSPSQSTSREASFAAMKEEILKVLPSDGGQKAITVKQ
                     DGSRLTIALSSNWLFASGEAALTSEGMTMLKRIGTVLGPLSDKFVQVAGHTDNQALSK
                     TLQKTFSDNKALSWARAENARRALVTGGMSPERTKAVGLADSRPIASNATEQGRQKNR
                     RLELVIVQGPTVASTTGKTTEERDRLAALAPSY"
     gene            complement(22762..23964)
                     /locus_tag="PK063_12830"
     CDS             complement(22762..23964)
                     /locus_tag="PK063_12830"
                     /inference="COORDINATES: protein motif:HMM:NF012894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HMZ97982.1"
                     /translation="MKHVCVVPVLLSAALLAACTSTPAPNDSASRALNEMKAVARPIP
                     PKPDPRDLRIAELERQKTDLEGELDRLRSSSAADSDRSKARITELENQLNQRDRELAG
                     LRNAAGDKDRLAGQLSDADRRLSAKDQELAALKQSAADKERLAAELAALQGLLATKDQ
                     ELAGLKHNAGDRDRLSSELAQAKQHIADLERQLSGKDQELGTLKGAAGDRDRLVADLA
                     AAKQRASDLENEIGRRDHEMAGLRGALDQQKTSLAEAKNDLSKLLQAEVSKGNVTMKQ
                     LGDQLTLGLATTLLFDSGEATLKPGGADVLNRIGSVLKNYPDRSIHVAGHTDNVPIKG
                     RLAKRFPTNAELSQARAESARQALTEGGMAADKISAKGHADSRPIASNSTAEGRQKNR
                     RVEIVVGQ"
     gene            complement(24033..24458)
                     /gene="mscL"
                     /locus_tag="PK063_12835"
     CDS             complement(24033..24458)
                     /gene="mscL"
                     /locus_tag="PK063_12835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HMZ97983.1"
                     /translation="MGMMSEFKEFAVKGNVLDMAVGVIIGGAFGKIVSSVVSDILMPP
                     IGLLMGHMDFSSLFIPLSEEAKGKSLAAAKAAGAATINYGVFLQTLLDFTILAFVIFL
                     VVKQMNRFKKATPPGPPPAPPKEEVLLTEIRDLLKNQRH"
BASE COUNT         4965 a         6633 c         7373 g         5561 t
ORIGIN      
        1 gaagcctggc tggataaggt acggagaacg gcctcaatcg accggaaatc tcccgaggaa
       61 ggaaaggccc ctgccaagtc ttgcgcgctc acacgtcact ccttcgtacg cactgaggga
      121 actgatgcgg ccagcagtgc cgcccaccgt aaagtttgtc cggctggtgg taatggccct
      181 ccagaatcat ggggagcacg aatacgtatc tcagtgcgct tcatccctgc aggattcgca
      241 tcatatcacc aagccggatc gtgcggtgag tgatgattga aattttgcaa cgtaattggg
      301 ccctagtgca gtagggccgt ttatctgcgt gaagggcggc atcgggtgcc accagcccat
      361 aggtattcgc agtgagaatc agatgtgaat cgatgatgtg tgtgctggaa gaaggagact
      421 cgccgagggt tgcttgcctt tccgtccccc ctgcaggttg cagagactgg aaggcccttc
      481 tgccattgct gagtttggtg ccgaaggcgg gacttgaacc cgcacggctt gcgccacacg
      541 cccctcaaac gtgcgtgtct gccattccac cacttcggca accgaatcgc tttccgtcaa
      601 cacatgaggc agggtatgac gagccgaacg ccgatactga atgggccgtt cttgctacgt
      661 agtccccgga cctcagagga agcgcattat agaagtggtc caaaatgctt gtcaatcaac
      721 tagttgtccg gtagaatctg acgcgtgctg cgtggacacg tggcatcccc ttcccatata
      781 cagcgatcag cggaccaacg ttcgagatga cgcctctctc agccccacat atttcatgca
      841 caggtcggca gacggacatc gccgcgctct ttgacgtcga caatacgttg ctccccggac
      901 aagccagcga agtgcgattt tttcgctttc tctggaagcg aggactcgtg ggctggcgtg
      961 aggttcggga cagcattcac tgggtgctgc ggtgtgcgcc tccggtttcg ttgcatccgt
     1021 tgcgggagcg caagctctat ctggccggaa agggtgcggc tgaggtcgag gcgttggccg
     1081 aagaattttg ccgtaccgaa ttatgtcccc gtctgtccgc ccaggggctc tctcgcatgg
     1141 atgagcaccg tcgagccggg catcatattg tgctggtgac cggatcgctc gatttcctga
     1201 ttgctccgct ggccgcattg ctggaggtgc cgaccttgct ggccgccagg ctggaacagc
     1261 aggaacagca gtttacgggg catgtctgcg cgcccctccc gtatggcccc ggcaagcggg
     1321 aactgattgc gcgtctgacg cgggaatcag gcattgatct ggcgcagtcc tttgcctacg
     1381 gcgatagtcc cggcgacgtc gagttactcg agatggtcgg tcatccgttg gtcgtgaatc
     1441 ccattcgcgg gatggaccgt atcgcgcaac gaaacgggtg gccgatgacc acatggaaat
     1501 aaagattgcc gcaggcccat cgtcacgaag tgatcagcca gatcgatcca cgatgctcag
     1561 agtaacggaa atatttcaca gcattcaggg cgagtccacg cacgccggtc ggcgctgtgt
     1621 gttcattcgt ttgacgggat gccccttgcg gtgtacctgg tgtgataccg cctatgcatt
     1681 ctacggcggt caggatctga cggaagagga cgttgttgcg caggtccggg ccttcgggtg
     1741 caatttggtg gaagtgaccg gcggtgagcc gctcagccag gcggcatgcc tgccattgtt
     1801 gaggaggctc tgtgacgagg ggttcgaggt gcttctggaa acgagcgggg ctgtcgatac
     1861 ggccggcgtg gatgagcgag tccacgtggt gctcgatgtg aagtgtcccg gaagtggcat
     1921 ggtcgatcgc atgtactggc cgaatgtgga tcgactcaca cgtcgggatg aagtgaagtt
     1981 tgtcatcaaa gaccgcacgg actatgagtg ggcgcgcaag gtggtgcgca gccgggatct
     2041 tgaggcgcgt tgcacggtgc tgatgagtcc cgtttttggt gaagtcgatg cgcgacagtt
     2101 ggcggaatgg gtgctggctg atcgattgcc ggtgaggttt cagttgcaga tgcataagca
     2161 gatatgggcc cccgatatgc gtggcgtgta agccctgcgg attggccccg tcggcagagg
     2221 aaagaataga gaacggcaag aaccagggag gattgatgaa gaagatccaa gttcaagcac
     2281 aggttgggcg ggcagaacaa gaaggtgccg aggtgctggt attgctctgt tgcgaggggg
     2341 cgtcagacct ttcgccggaa gctgccgcca tcaacaccca gcttggtgga cagctcgcga
     2401 ccttgattca gcgcggtgaa ttcgaaggca agcttggcga ggggttgctc gtgcacacgc
     2461 agggcaaggc caaggcgaag cggttgctcc tggccggctt ggggaaagaa aaggatttgc
     2521 gcctggacgc cttccgccag gcattaggcg ctgcagtcaa acgcgtccgc caggccaaag
     2581 tgtcttcatt cggcgtggtt ctgccgggtg cggttctgga agaaattcct gttcaggatg
     2641 tggcccaggc catggccgaa ggggccatcc tcggcaacta ccaatttacg gcgtatcgga
     2701 gttcgaacgg aagcaaaccg gtagaggtcg agcggctgac gatctacgtc gcacaaacat
     2761 cgctgctggc gcaggtcacc gagggcatcc ggcgcggcgt cgcgacggcg gaggccacgg
     2821 tcctggtccg cgatctctgt aaccatccgg ccaatatcat gacgcccggc cggatcgtgc
     2881 aggaagcaaa ggctgtggcg aaagaaccgg gcgtcaagct gaaggtgctt gaacagaaag
     2941 atatggaaca gcttggtatg ggggccttgc tcggagtggc gaagggcagt catgagccgc
     3001 cgaagttcat cattctggag tacaagggcg cgaaggcaaa gaaaggagat cccccggtgg
     3061 tcatggtcgg caagaccatt accttcgaca ccggcggtat ttcactcaag ccggccgaga
     3121 atatggaaca catgaaggcc gacatgacgg gcggcgccga ggtgctggcg acgatgcgag
     3181 ccgcggcacg actcaagttg ccggtgcatc tggtgagcat attgcctgtg gcggaaaata
     3241 tgccgggcgg tcgcgcgatg cggcctgggg atatcgtcaa gacgctttcg gggaaaaccg
     3301 tcgaagttca aaacactgac gccgagggcc gactgatcct ctccgacgcc ttggcctatg
     3361 ccacccgcta caagccggct gtgttgatcg acatcgcgac gttgaccggt gcctgtgtcg
     3421 tggcgctcgg tcaatttgcc atcgggatgt tcggtaacaa tgatcagttg aaggaacatg
     3481 tccggaatgc cggcatgcga gctggtgagc gggtgtggga aatgccgctc tgggaggagt
     3541 atttcgaaca gttgcgcagt gatgtggccg atatgcggaa catcggtggc cgtggtggag
     3601 gcatgattac cgcggcactg ttcctgagca agtttgtcgg ggactgcccg tggatccatc
     3661 tggacatcgc cagcaccgac tggagcgagc gtgagcgagc ctatctcccg aaaggtccca
     3721 ccgggatcgg cacgcgcctg ctcattcaat tcttgctgga ccggaccctg ccctagcggc
     3781 aaccggtgcg tgaggcggcg tcagccgagc atctctctgc ttctcaccca gatcgtcatc
     3841 gtagggggtt atgacattac gcgagcacat cggtcagctg ttcatgatgg gatttaccgg
     3901 gaccacggtc agcaaggacc tggcctcgtt tctcaccgcc tataagccgg ggggcgtcat
     3961 cttctttcgt cgcaatctcg aatcggtcca gcagatcgtc gatctcacca acggactgca
     4021 gaagttgtcg ccggcctcgc cgctattgat cgcgattgat caggaaggtg gacgggtctc
     4081 ccgactgccg gccgaattta cgatctttcc cccctgcggt cagctcggcc agtgtcattc
     4141 cagtgaactc gcctattccg ctgcagccac catcgccaaa gaattgcgag ccgtggggat
     4201 caacatgaat atggcgccgg tgctggacgt gaacagcaac cccgacaatc ccgtgatcgg
     4261 tgatcgggcg ttcggtgccg agcctgacgt cgtcgccgac atggggctgg ccacgatcgg
     4321 cggcttgcaa gacaatatgg tcgtggcctg cgggaaacat tttcccggcc acggtgatac
     4381 ggcaacggat tcgcacaagg agcttccggt cgttgacgcg gggattcaac ggttacgcga
     4441 gacggagttt cccccgtttc agcaggcgat ccggcaggga gttgccagtc tcatgacggc
     4501 ccatgtgttg tatcgggcct tggatcccga tgcgccggcc acgctgtctc ccgctgtgat
     4561 ccagcggcta ctgcgcgaag agtttcgtta cgacggggtg gtcttcactg acgacctgga
     4621 gatgcatgcg attatcgatc atgacgggat cggcgaagcg gctgttcgtt cgttcgtggc
     4681 cggatgtgat gtgttgctga tttgcaaaga ccaggaccgg gttatgacgg ccatgcaggc
     4741 gatggaacgt gctgtgcaaa acggccggat cacacaagaa agactggagc agtccttggc
     4801 ccgtgtcgca cgactcaagg cacgatacct gatcccctac aagccggtga cgatctcgga
     4861 tgcccgtctg gtggtcgggt gccgttcgca caaggtgttg ctggactcat ggcataaagc
     4921 ctatgcccgg ctgccttcct cgaaggtgtc ggagcacgat gagccggcgg cggcgttgga
     4981 ttcaccggtc acgcatgtct aacgcatagc cgtatgcggg tggggcatcg tctgaagcag
     5041 cggcgcgagg gccaatctcc tgagaggaac cggtgctgga ttttcctctc gagttttgat
     5101 tcactagtgc tggattgggc tccattccat ccattcatca tactgaggcg ccatgggcat
     5161 caagaaaggc gacattctcg acgaacggaa acgctttccc gattcctgcg ggctggtggt
     5221 taagtgtacc ggtggcggcg agggttttca gaagatcttt tgttgtgggc atgaactgac
     5281 tgaagaggac ctcgtgtcgg agatcgtatc gtcgaggggc cggaaacgag gaaccttact
     5341 gccgggggcc atgctggaag agcggcgaca gtttcctgat tcctgcggcc ttcgcctcat
     5401 ggtgatggat ggcggcgccg gactgcaagg catcgactgt tgcggccatc tcattacggc
     5461 cggggcggtg catggcttga gattcggtca accgctggat gaaggggctc ctatgccgac
     5521 cggtccggca gggcaggcgt aatgcgcgca cccagtatgc cgggggcgga tgagaagttt
     5581 catcgaccca gtatgcgatg gtggctcggg ttcatggatc agctggaccg gcttggctat
     5641 gttgcggccg gattcagtct gctggcgctc tgcctgatca ttttcgttca tgcctggtat
     5701 atcttcctgg ctcgacccgt tcagctcgcg ctccttcctg ccgccctcaa attattgaac
     5761 gatctgctcc tggtcatcat tcttttggag ctgtttcgca cggttgtgcg atttcttcag
     5821 acggaagtgc tggaattaga gccgtatttg tccgtgggga tcattgcctg tacgcgaaga
     5881 ctgttgacgg ccagcgccga actctcctac cagcttgaag cggtggctaa ggaaagcagg
     5941 cacgaattat ttcagcaata tctcctggat gtcggcttga atgtgctggt catcatcatc
     6001 ctcatcggag ggctgtacct gcttcgctcc cgtccgtcga ccgaacgtcc ggccgtctcc
     6061 tgagcgggag tggaccgaat agcagggggt gctaggtcct tcttgccctc ttcctatctc
     6121 ttatggcatc atgcacctct tcttggaggc atggtggcca cattgcttga atatgtggga
     6181 tcggtccata tctacctcgg gccctaccga ggaaatccta ttgccttgta tctgaggcgt
     6241 acggaggtgg gatgtcagat cgggcctcgc gcctatccat ggaatgatgt gataggagcc
     6301 ggggaaactc ctaacaaagc cgctgcggat ttcgaggaaa aatggaaggg caaggggctg
     6361 gctgctgata tgtattcagg cccgtcctgg gaaggtggaa ttaaacccga acggcctgcc
     6421 cctccaaaac ccgcggctcc cccgaagcct gcggccgctc ctgcgtctgc tccagtcact
     6481 tcagctgccg cacctgcccc agctgcaccg gcagcggctg ctgccaaacc ggccgcccct
     6541 gctgcggccc ctgtcgcagc cgcacccaag gtcgccccag tcgcgccaac cgaagcgtcg
     6601 tcttagtttc tccatcgtcg aagtgttcat gcagcggggt catgcgcgcc gagcgtgact
     6661 ggtgtgttca agcgccggac ttgtggcgag tttgctgcgc cgtatgccgt acgtggcgta
     6721 gacaacgatt ccgatgaccg tccacacaaa aaaccggatc caggtcatcc agggaaggaa
     6781 atacatcaag cctaagcagg ccagcacgcc cagcatggga atgaccggca tgaatggcat
     6841 gcgaaacggc cgaggatggt tcgggttggt gtaacgaagc acaatgattc cgatacagac
     6901 gaggacgaag gcgaagagcg ttccgatgtt tgtcatatcg gccgcttcgc caatgggaat
     6961 caaggcggcc atgatggcca cggctatgcc ggtaaggtag gtggcatggt gaggtgtgcg
     7021 aaatttcgga tgcacgcctg acagccaggg accgagaagc ccatcgcggg acatggcgaa
     7081 aaacacgcga atctggccca gcatcatcac caccagcacg ctcgtgatcc cggccactgc
     7141 tccgaccgct acgatggcgg ccccccattt gaagccggcg acccgcaatc cttccgccac
     7201 cggggcatgg atgtcgattc gcgaaaacgg caccaggccg gtcaggaccg ccgccacggc
     7261 aatatacagg agggtacaga tacccagcga ggcgaagatc ccaatgggaa gatcgcgttg
     7321 aggatttttg gcctcctccg cggtggttga gacggcatca aacccgatat aggcaaagaa
     7381 tacgatggcc gccgccgcac ctacgccggc aaatccgaac ggcatgaacg gtgtccagtt
     7441 ggtcgtatcg acggaggagg tcccgacggc gatgaaaaag acgatcacgg ccagcttgat
     7501 caggacgatg ccgcaggtgg ctcgggcact ttcctttacg ccgacgatga gaatgccggt
     7561 gaccaatagg acgatgatcg cagccggaat attcgcgatt cctccgtccg ctcccggggg
     7621 atgcgtggcc cagtaaggca gttcgaggcc acacagtttt agaatgttgt tgaagtagcc
     7681 cgaccagccg atggcgactg ccacgcaagc cacgccgtat tctagaatga gattccatcc
     7741 cgtcagccag gccaggaatt ccccgagggt cgcataggaa taggtgtacg cgctcccagc
     7801 caccgggatc atggccgcaa attccgcata acagagcgca gcaagggcgc aggtgatgcc
     7861 ggatagaatg aacgacagga cgatccccgg cccggctcct ggtcgatgcg catcgccgac
     7921 gatcgcggta ccgatcagga cgaagatgcc tgtgccgatg atcgcgccaa tcccaaggcc
     7981 ggtcaggtcc caggcggtga ggcttcgttt cagacgatgt tcgggggcgt cggagtcagc
     8041 gaggattcgt tcgatcgatt tggtgcgaaa cagcggattg cccacgccgt gtcctctctc
     8101 cggtgacgtc actcccatgt gcgctggcat gggcgaatga gtcccctctc atgtggtggt
     8161 cccgcgctgc ggagacaatg gtcgaagcgc cggacgacgg gaggctgccc gtaagaatgc
     8221 ctcaaagagc tgccgatgca gccggtggcg ctcaaacaga aattctggat gccattgcag
     8281 gcctagaaaa aatgggtggc cgggatgttc aatcgcttcg acgatgccgt cgggagccgt
     8341 cgcgctggcg atcaatgcgc gccccacgac tttgaccgac tggtgatggg agctgttcac
     8401 cttcatgcgc gggcgtttca tgatgcgctc gaggagcgtg ccgggtgtga tggagacgct
     8461 gtgagcgagc tgaatagccg gtgtcgtctg ccggtgttgc agtacatcgg ggacctgggc
     8521 tggaaggtcc tgatagagag tccccccgaa tgcgacattc atggtctgca tcccgccgca
     8581 gatggccagg gtcggcagat gattgcgggt tgcgagatga acgagatcca attcgaagct
     8641 cgagcgtcgc tgggcgacga tcggaaacga atattgcttc cgttctccgt agagcgcggg
     8701 gtctaagtct ggaccgctgc cggtgagcag cagcccgtcg atggtgcgga ggaggcggcg
     8761 acgcgccgca cgatcagcca caaggggaag gatgagcggc accccgccga gttcttcaat
     8821 tgcgcggacg taccgcgccc ggagaaaata ggtgggctct ttgccgcccc attcctgacg
     8881 atcaccggca ttgaagtcgg gcgtgactcc gatgacgggt ttcatactat cggatcggtt
     8941 ccaaagggag cggcaggggc tcttgagggg tatagtcccc ggcttcccgc gtgggttcgc
     9001 tcgaggaaac accgaggaag cgaatcggct tatccccctt cagatggtcc ggcgtaatga
     9061 tgtaggtgcc gtacatgctg gggatccaaa tattctttgc ggtttgttcg ctcccgcctg
     9121 agaagccgta cgccagtccg ccaaccactc cgccaccgat agcaaacgcg agtttgagcg
     9181 ggaagtagat gatggttgcc agcgcggatc ctgcttgaat gccgacccct gaagggctgg
     9241 catcgttcga ggagacggga acgttggatg cgctgcccga ttcttgtgct gccaccggca
     9301 caatgaggat ggccagtgag caaatcgcca ccagaccgag aaccaacgcg tttgaccaga
     9361 ggctgcggcg tcttttcgag gacagattga cagagacgtt cacgttaagt gcctccttcg
     9421 tgctgaaatg ctgacggtgt gaaattagaa gatgagtgcc gatgaacttc tacaatagcg
     9481 agtactccgt tgtcgttata acaaattcat ccccattttc aaaccccttc cgcgtttgtc
     9541 gcaggtggtc ctccgctctt caacgatcag gcgactcttc caggtctaat tccaggcgaa
     9601 tgcgctccat cacctgttcg ggctgctcgg tcatgatctg ccggagttca tcggtaaagc
     9661 gtgccgcgtc gatcacctgg ttatgttgct caatgcctcc gtggagagcg agattgagtg
     9721 cgcaggtgca tacggattgg ataaagagtt catccgcccg acgcgtcagc tcagcctgtt
     9781 cctcttggca gatcttgtgt aattgatgtt caacccaggt tgaaaagccg atcgcccggc
     9841 gcgcctcctc gacgtgcttc atagcgatgt cgaggctgac ctgtatgccg cctttccaac
     9901 tgcgtttttt cacattaaac acgcagcgca ggagatcggg ccgatgctcc accggttcgg
     9961 gtccgaaaaa aaatgtgacg cggtactggc ttggttctgt cgcagcgggg ggaatactca
    10021 taggtcgtgg aaagcattct atcattccgg agcgcggaga gcatgtctat tgtcgagtgg
    10081 tttcagtttc gaaatgacgt tatgatgcga tcatgaaaac gtctgctgat ttcgtggctc
    10141 aggtcgatcg tattcaagaa gccattcggg cacatcccgg gattgacggg tggctgtttt
    10201 atgacttccg ccatctcgat cccattgcct atcgcgtgtt gttgttagat ccgtcgatgc
    10261 atgttacgcg ccgttggtac tattgggtgc cggcggtggg gatgccggtg aaattacagc
    10321 accgcattga accgcatgtg ttggaggcgt tgcctggtga ggtgcggttc tatgtctcct
    10381 ggcgagaaca gcagacggcg ctaagggcgc ttcttcaatc ggcgaaacgc attgccatgc
    10441 aatactcgcc gatgaatgcg attccgtatc tttcgcgagt ggacgctgga acgttggatc
    10501 tcctgcgcag ctggggtctg gagattgtta cctctgccga tttggtccag caatttgaag
    10561 ccgtgtggga tgaggcgcag ttggcgtcgc accaggcggc tgccacgggg ctgcgagcga
    10621 ttgtggatga ggcgttcggg tttatcggga catccctcgc ggcaggctct tcgctcaatg
    10681 aatacgggtt gcagcaatat atcctgtctc ggatgcatgc tcgcggcctc gtcacgtcga
    10741 gtccccccat tgctgcagtc aacgcccata gtgccgatcc tcattatggg ccatctgccg
    10801 agggctctgc tcccgtccgc cagggggacc tcgtgttgat cgatttatgg gctaaacagc
    10861 cggaggccag ggccgtgtat gccgatatca cctggacagg tttcgtgggc aaggtcgtgc
    10921 ctgccaggca gcaagatgtc tttcagatcg ttcgccaagc gcgagatgca gcggtgacat
    10981 tcgtgcaagc gcgcgttcga gagggcacat ttccctacgg ctgggaggtc gacgatgtgt
    11041 gtcgacaggt cattcaacag gctggatacg gagagcattt tgttcaccgg actgggcatt
    11101 ccataggtga agaagtccat ggcaatggcg caaacatcga caatctggaa acgcaggatg
    11161 ctcgccggtt gctgcccggt acctgtttct cgatcgaacc gggaatctat cttccgggag
    11221 acttcggtat tcggagtgaa ttggacgtgt acctttcgac caatgatgcg gtggtattcg
    11281 gtcaaccggt acagaccgaa cttgtcgcga tcacccttcc caccacgtga gtctggtctc
    11341 atcctgaggg atggcctccg cctttcttga caccctttgc atcgggcagc tatcgtgaga
    11401 gatcgactgg ccgcagaggc ctcgtgcctg gttggcccct atttgccgag gaaggatacc
    11461 gaacatgttt ggcacgatgg gattctccga actgattatc atcctggtta tcgtcttgat
    11521 tatttttggt gccggcaaac ttcctcaaat cggggagggc gtgggcaagg ccctgcgagg
    11581 gtttaagaag gaagtgaatg atatccctgc tgccgatgcc actcctgaac agggtgaagc
    11641 tgcaactcct tcgtctcagg cacagatacc gcctgttgca gaagttgccc agactgctca
    11701 gcccgcgccg gtggctcagg ccgctcccag tctcaaacct accgcgccct acacgcctgg
    11761 tccggagtta acacctggga cgacagcagc cttgatggcg gctgctgcgc ctcaggggcc
    11821 tcaaacggcc caagcgtcta agccccgggt cgccacggtc acgccaacac aggctgcccc
    11881 cggctcggtg gtggcacagg ggcatcaacc tccgacgatg gaagatcgca tggcggctcc
    11941 ggcaccggtg atgcggggac agtatccccc tcttcctgcc tcggctcaga gtaagccggt
    12001 ggccaagcgt ccttctgcta ttgttaataa agacgcagtg gctcgggtac aggctgcgca
    12061 ggctgctatc cgggcaaagg cagcgcagcc tcagccggcc gccttttctc cgcaagacat
    12121 gcaggggctt ggcgagggac tgggagacgc cgtgcggact ttccggcagg cggtcgcgga
    12181 tgtgcggagt tcggttgatc ctcagatgcg gaccattcga gcagaaatgg attccgctca
    12241 aaaggaactg gaacagtcga tcgaggcagc gaagcaagcg cccgtgctcg acgaggacac
    12301 tcctgccaag ccgctctaac cgcgtggagt ttggatagct ttcgtttgga tcggtaatgg
    12361 gatgtgttgc cccaggggac ttacagcttg atgcgtgcag ggtctatatc gtcgtgctgg
    12421 gccgatcgac ataccacggt gaaggaaatt gtcacctgat ttctggtcta ttcctctcgt
    12481 gcagcatgcc ccgaccattt taacgctcac atgagttccg aatcattcct ccgtaacccg
    12541 tcctacctcg cattgttatt gttgttggta gtttccttga ccatatccgg ttgctatgtg
    12601 gaagtcccgc cagcgactcc cgcggtggtt tccgtgaggc tgaacgaatt actcgctgat
    12661 cccgatccgg aagtgcgtcg cacggcggca gaagggttgg gaaagatcgg ccacccatcg
    12721 gcaagcccag ggcttattgc tgcgttggca gatcgagatc cccacgttcg cgcagctgca
    12781 gcactcgcct tgggtcgagt gggtgatgca aagagtgggg cggcgcttgt ggaacatttg
    12841 tcggattcgt ctgagtctgt tcggactgcc tccgccttgg cgcttggcga aattggaact
    12901 tccgtcagtc atgaggagca gattcttcgc gcactccgcc agccggaggt ttctacccgg
    12961 ctggctgcca gtcgagccct cctcagtttg gagacggttt cattttcaac ggatctcctg
    13021 tcggccctgg acgatcccaa tgcgcaggtg cggcaagggg ttgtagcggt tctcagtgag
    13081 acaggggata ggagacctct accaagtctg atgaggcttt tgcaaaccga tgaggatgcg
    13141 ggagtgcgcg ctgaagcagc gtttcggctg ggaaaagtgg gagatgccgg tgtggtgcct
    13201 gcgttgtccg tggtagccga gaaggattcg aatccgacgg ttcgacaatg ggcgcattgg
    13261 gctgttcggc agattacgac atcgcccggc ttcggttcag ggaatcgaca aggtcaatga
    13321 ggcgagtctg agccaccgga tcaatgtcgg taaactgaat gcccatacct ggaaagagca
    13381 gataccgctc tggcttcgac cgtgtccagg ctacttttgc acgtgtggca aatttctggt
    13441 tcggtcggtc aggtagggca aattccacgg tcagttctgt gcccggtgcc aacggcgtac
    13501 tactttcgat aaacaatccc cctccgccga tcccgccagt caagctatca aaatgcttcc
    13561 cgtcctccgt ggtgcaatgg actttgatgg caaggggagc gcgtggatgc gatcgactat
    13621 gggcaaagcg ggcatcttca tcaacggaga gcatatgctc gatgagggtt ccccagctta
    13681 ggatactgag ctgttgtccc ttgtgatcga acaacgatac ggtttcctgt tcgcaatcaa
    13741 taccgagcgt tttgccgtgg tgctctcgag tggcagtgac gggaaatttc atcggtgagg
    13801 tctcggaggg tccgcagtga atcgatctgt cacgaatagg aatcgtgtgt cgagagtgtt
    13861 tagcaggact actcgctctg cggaatgcct tttacagaat gaaccagatt cagcacgcga
    13921 cttcgggtct ctgatgcgat atctgtgaaa cgtacaccca taccagggct aaaagtatac
    13981 tggtcggcct tggggcaaac ccaggcgatc actcccttgg cggacatcca ctcgctgggg
    14041 tcttctggta gcgtgaattc catggcaagt ttcgttccga ctgccaaggg ggcgaggctc
    14101 tcgataaaga gtccgccacc gccgatgcct ccggctcgac tctcgaactg catgccatcg
    14161 ggggtgtggt atttgacgcg gatagaaagg gagatccgcg gttcagaacg ggcttcacgg
    14221 gattgctggg gctttcgata ggtcaggatc tgatcgacga gaaaatccca cgcgaggctt
    14281 cccattggct cgccgttgat gccaagcaac gtgatcgatt cctttgagga atcaatttca
    14341 atcgtcttgc ccttgtgtct tgtgctggat acgacgggga atttcacaag ccgcccttta
    14401 caaacctaca tgttgcaaca aggcatctgg tgcaagtata gcccatggat cgaacttgtc
    14461 gataaaaacc tgcgattgga gaagtttggc gaaggagagg tcggtaatct actgcgaagg
    14521 ggaataaaaa aaaagagggg gcggacgccc cctcccgatc gctgaaatgc gcttaataga
    14581 cgagtagttt tgaggggtta ggcgctcttg acgtctttgt cctgttcgaa aatccgaata
    14641 ggcgcgtgtt ttccgctgat ggcatcttca gtgatcacga cttccttgat ctgtttctgc
    14701 gacggggcgt cgtacatcac atccagcatg gcctcctcga gaatcgcacg taacccacgg
    14761 gcaccggtct tttgagtaaa ggctttccgg gctacagcac ttaacgcacc ttcagtgaat
    14821 cggagcttca ctttttcgaa ggacagcagc ttctcatatt gcttggtcag cgcatttctg
    14881 ggctcggtga gaatccgaat gagcgcttgt tcgtcgagtt catcgagcgt agcaacgacc
    14941 ggcaaccgac caataaattc ggggatcaat ccgtacttca acagatcttc cggctggaca
    15001 tgcgggagca gttcgcccaa tcgaatatca ttgcggcccc ggacctcggc tccgaacccc
    15061 atcgatttcc ggttcagacg ctgctcaata atgtgttcaa gcccgacaaa tgcaccgccg
    15121 cagatgaaca aaatattgga agtattgacc tgaatgaatt cttgatgcgg atgtttccgc
    15181 ccgccttgag gggggacgtt cgcgaccgtt ccttcgatga gcttcagcaa ggcctgttgt
    15241 acaccctcgc ccgaaacgtc tcgcgtaatc gacggactgt cactttttct gctgatcttg
    15301 tcgatttcgt cgatatacac gattccgcgc tctgcccgtt cgacatcgta atcggcagcc
    15361 tggagtaatt tgagaatgat gttttctaca tcttctccga catagccggc ttccgtaagt
    15421 gtcgttgcgt cggccagtgt gaagggaaca tcaagaaatt tggccagcgt ctgagccaga
    15481 agggtttttc ccgtgccggt cggtccgacg accagaatgt tgcccttttg cagttcaacg
    15541 tcgtcgacgt ctttgtcctt tgcggagatg cgcttgtagt gattgtgcac ggcgactgag
    15601 aggatacgtt tcgcacgatc ctggccgacg acatactgat cgagatgatg tttgatctcg
    15661 gccggcttct tcagcttgga ggagatttcc tccttcgctt cttcccagtc ctccgcaatg
    15721 atgtcattac agaggtttac gcattcgtcg cagatgtaga cggtaggacc ggcgatgagt
    15781 ttgcgcactt cgtcccggct tttaccgcag aacgagcaac gcaggtgccg atcaatcttt
    15841 tcctgtttag ccatgctgcc tcctgtacac caaaggtcaa ctagctcttg ccgccatcct
    15901 tccctgagtc cgttgagccc acgggtttaa ggctcttcag ggggcgtgta atcacttcgt
    15961 caatcaggcc gtagcgtttg gcttcctcac tggacataaa gtagtctcgc tcggtgtcct
    16021 gggaaatctt atccagcggt tgtccggtat gtttcgccat gatttcattc aggcgttcac
    16081 gaatcttgag gatctcccgg gcatggatgt cgatctccgt tgcctgtccc tgaaatccgc
    16141 ccatgggttg atggatcatg acgcgggcgt tgggaagtgc atagcgcttg cctttagtcc
    16201 cggctgttaa aagaaacgcc cccatgctgg cagcctgccc caagcagatc gtgttgatgg
    16261 atggtttgac gtattgcata gtgtcgtaaa tgccaagtcc tgccgttacg cttccgcctg
    16321 gcgaattgat gtacagatta atatccttct ccgggtcctc tgcctccagg aacaggagct
    16381 gggcaataat caggttggcg aacacgtcat cgataggagc cccgaggaag atgatacggt
    16441 ccttgagaag gcgtgaataa atgtcgtagg cacgctcgcc gcggtttgtt tgctcaacaa
    16501 caatcggaac taacattcgg ccgaatcctt tccgctagag gactaacagg tggaaactcc
    16561 tcagtttacc atactcatcc tgccgggaat tggtgatgac cgcccgacct cagtacccgc
    16621 gactcctgat ttaagagcgt ttagccctga atcatcgcgt gcttgtatac aaaatccaat
    16681 gctttgtcag ccaagattct tgaccgaagg tcattcaggg tgtcttgacc gccggcttga
    16741 atcatgcggg tgacttcctc gacggagagt ttcacttcag cagcgagccg cgcgatttcg
    16801 ttgctgagat cttcattggt caccgtgatg ttttctttcg ttgccagcgc ttccagaatg
    16861 agcccgacct tcacgcgacg ctccgcttcc ggacgatatt cttcctgcag ctgtttggct
    16921 tcgtcggctt gagaggcacc gggcgatccg tctgccgcgt caccggtctt ccgttgacga
    16981 gactgcaatt gttgacgaac catcgcagag agttctcgtt ctactagcgt tccgggaaga
    17041 tcaaaatggt gggtttcggc caatcgcttc aaaatcgtat ctttgtagga gtcctcaatg
    17101 tcctttttca aggcacggtc catttcggcg tggagcttct ctcggatttc ctgcagagat
    17161 tgatacgggc cgcaatcttt cgcgaattcg tcgtccaggg ccggaagttg tttgcgtttt
    17221 atggacttga cggtgcagcg gaagttgacg gtctttcccg ccactcgcgc atcgggatgt
    17281 gtcgccgggt aagcctgggg aatggtgatg acgtcaccct cctttttccc taggaggtgc
    17341 ggttcaattt cgattccgag gacggaagac tgagaaccca ttttatggag atgtcccgtc
    17401 ttggttgttc catcgagcgc agcaccgtcc actgtgccgt caatgtcgac aaccgcatag
    17461 tctccatcgg ccagagtcgt tccggctggc gcgggatgca actgagccat ctgctcacga
    17521 agaacctcaa gtgccttttg cacctgttca tcggtgactg ttctctgatc ctgttttaga
    17581 gagattggat tcggagcttt gtaatcccga agctcaatcg ttggcttaat ctcaacggta
    17641 gccgtaaagc taaaggggga gtctttcttc actttgaccc gttccaacgg cggtatttct
    17701 acaagaaccg gaacgatgcc cgcctgccgg atagctcgat cataataatc cggcaccaag
    17761 ctacgaatga catcttcttc aatcgttttg gcgtagcgct tctcaagcaa ttggaggggg
    17821 gcttttcccg gacggaagcc gggaatgcga acttgccgat tcaattcaga gtacgcctgg
    17881 acaaaccgca ggttcacttc gtctgcagga acttcgattt tgagcgctcg cttcatgggg
    17941 ccgagttcgg tcatttccat cttcataagg ctattcactt tctccgagtc cgatagtggt
    18001 tggtgcgtca tgccaggtca tagaggtggt gcgagagggg ggacttgaac ccccacggtt
    18061 acccacgaga tcctaagtct cgcgcgtctg ccagttccgc cactctcgcg cgacgctgag
    18121 tactaggctg ctcactgatg gtgcgtaaga aatggatata catgtgtaaa ggcacgatga
    18181 ataatgacat tttgtaccgt cgatcgtgtc tgcctgtcaa cccatacgca ggtggggccc
    18241 gtgtgctgat ttgtgattct gaggggaact cggccgtaga gaaaattgta tggagtgaag
    18301 gcctccatca ggcggttgtc tctctcgtgc tgcgaggctc cttctcctgg tattgcccta
    18361 catgaggaac ggtataatgg acacacaggt ctgattcact atcgccatcc gaacgttctt
    18421 cgaaataaag ggggacaccg tatgaaacgc cagtctgtga cagctgcact tgggtgtctc
    18481 attctgctgt gcggcttccc gctttcgagc gaggcctatc gagattattt tactgacgca
    18541 caaaagcaag aattagtaaa gattcaaacc gtcttgattg aggcattggc cctaacagac
    18601 aaaggcgctg gcaatgccga cggaatcttg gacgtggcca tgaagcgcat gggcgagctc
    18661 ggttatacaa cagtctcgga tccacacgtg tcccacgatg tcgtcgtgcg ggtcaaatgc
    18721 gagcaaaaga agacctggga gggcacggca tccgcggggg gagacaatga tttgcctgat
    18781 gcgccgtccc gcttgtggaa aggtccggca tgtcagatta cgtacgcgtt gggtggtatg
    18841 aaggtcaaat ggcagaagga ggttcggaca gaatttgaag atgcggtcgg agctgcccaa
    18901 tcggctcagg caccagaccc ggggctgtat gccatgaatg cgcttcatga cgcgctggag
    18961 acatatgagt tcccccttct cctgaccgca gagtggggcc agcctgatcg gctgcttaaa
    19021 ttactcgata gtccgcaaac cagccaaatt cggaagctca agattatttc cttgttggga
    19081 gagatggttg ctgatgaggc gttaccccac ctcaccgagg ctttaaaaga caaagatctc
    19141 gccaagcaag ccgcggtcgc attggggaac atggggaagg aagggattcc tgtgctgatc
    19201 gacattttga agcattccaa gcaacccgag ttgcaagccg ctgcggctaa aggtcttggt
    19261 gatctaggca acattcatag tgactcgaga gtggtgacgc ctttactgga gatgcttgat
    19321 gcgcccggca tcgacattgt ggtgcaaacg gaggttgcgt gggctctcgg gcgggtgccg
    19381 gatcgacggt cggttgaacc gttatttgcc ctcgaccgga agctgcaaaa aatccgaaaa
    19441 gatcctcccg atccccagat taagaaatta aaggaggcgg tcttctggtc aatcaagcag
    19501 gtgtataccg aagaccagta cagttagcag ctaggcatgt atcctggtgc agtattgccg
    19561 cgttcaatag tccgtgacct ctccgcgatg gcgtcgctat cctgcgtcac cagccttctc
    19621 gtaatgggcg tgcagttcgc gtccaatgtc tgccggtcct gcaaaatagc attcccaact
    19681 tcgagctgtg aaaacagcgg cgactctgct atgaaggtcg agcagtgtcg aggaggtcgt
    19741 gtaagtaggt cacattaact gggccgggaa catgccaaga caacaatgag ggataggacg
    19801 atgagagata tctcgcgacg acgctttctg caaatatccg ctatgagtgg tggcgtgctg
    19861 cttttgggcg atctcgccga gcgcatactc aatgtgcctc ttctacgatc agcggcgttg
    19921 gcggcagagc cgattaaaat cggtattctg gacccgctat cgagccccta taagacgtct
    19981 tcgatccacg atgtacatgg ggcgaacgtc gcggtggatc tcttcaacaa gcgcggtggg
    20041 gtattggggc ggccggtgat gatcatggag gcggatgatg cctctaaccc tgataccgcg
    20101 ctcaaggcgg cgacgaaatt cgtgcaggac gatcgtgtcg atgtcttgat ggggacgttc
    20161 aacgctgagt gcgcccttgt tgtgtctgag tacgcgaaga aggcgaacaa gttgttcatg
    20221 gtcacgggcg cgcatttgcc tgagttgaca ggggccgcgt gtaattccca caccttcgtg
    20281 tttatgccca atgcgtccat gctggcgcag gccgttgtcc cgcagttggt gaaagcctat
    20341 ggcactcgtt ggtacatgat tacgacgagc tctttggatg gcaaagcgat ggctcaggcc
    20401 atggcctcga ctggtcttac tcatggagtg gaattcgtgg gtgagacact gatgcccttc
    20461 ggttcgacgg atttcacctc ggcactcagc gcggccaagg acaaacgccc gacgctcgta
    20521 gtgttgaacc tctatggatg ggatcttgtc catgccctta aagcgtacac caagttggaa
    20581 ttagccaagg ataaaatcgg tgtcggcggg atgattgccg gcgagcagat tggccgtccc
    20641 ctcggctatg caaataacgc cgggatctgg ggcctgatct gggaccccaa agtgaatact
    20701 gacggatcca aacgatttat ccagggagtc gtggagaagt acaatcatac tccgacatcg
    20761 cgttgttatc tggggtatgc ggccatgacg cagattctgg aagcgattca gcgggcaggc
    20821 acaactgaag cgtccgcgct catcaaggta ttggaaggac atgagtttga tggcctgaaa
    20881 gaagggcgat cgtacttccg ggcctcggac caccagcatg tgcaggatgt gttagtcgga
    20941 gaagcgtatg gcaaggaact gggactggga cactacaaga ttctggccac tgttgccggg
    21001 gagtctgtcg ccacggtgca atcgggtagt tgccagttgt aagccgagtc gtaatggtcg
    21061 gctctagtat gagggagcaa gtgcggcgag acgatctcgc tcctcagttg ttttccccgt
    21121 cgtcgatgca acggtaggtc cttgcacaat gaccaattcg aggcggcggt ttttctggcg
    21181 accctgttcg gttgcgttgg aagcgatagg tctggagtcg gccaaaccga ccgctttggt
    21241 tcgctccgga gacatcccgc cggtgaccaa tgccctgcgc gcattttccg cccgagccca
    21301 cgacagcgcc ttattatccg aaaaggtttt ctgaagggtt ttgctcagcg cctgattgtc
    21361 cgtgtgaccg gccacttgta caaacttgtc tgaaagcggt cccagcacag tgccgatgcg
    21421 tttgagcatc gtcatgcctt cagaggtcaa ggcggcttcg ccggaggcaa acagccaatt
    21481 gctggacagc gcgatcgtca atcggcttcc atcctgcttc accgtgatcg ccttctgccc
    21541 gccatcgctc ggcagaacct tgaggatctc ctccttcatg gctgcaaagc tggcctcgcg
    21601 cgaagtggac tggctcggac ttgttggggt cgcgcttcct gtgcggccgg catccttctc
    21661 cgaggatccg gcgtttttgt tggaagtcgc ccccgtttcc cgtggggccg tcgccgcttg
    21721 ggcacccttt tggcgtggcg aaagatcccg actcttttca ttcaggcgtt gttcaagtgc
    21781 agcgatccgg tgccgggcct ggtaaatctc tgcgatcatc gcattatatt gcgggaccag
    21841 cttgtcccgt tccatgaggc gcgagcgaac cgtttcgaag gcttgctctc ggtctctcag
    21901 ctgctgatcg agcgcactga tgcgcgcttt gagggaatca atcgttgccg tggctgtttg
    21961 taattgggcg gcgagactgt cccgttcggc attttcagac ttaatcgtgc ggagatcgtg
    22021 atcctgccga gcgacctggg cttccagatc catgatgcgg cggcgggcga cttcgagatc
    22081 ggaaattgct gtggagcggc cttgaagagc aaccagatct ttttctcgtg ttgccagttg
    22141 ctgttccaag cttccgatgc gctgacgggc ttgcagtaat tcattattgg ccatggccaa
    22201 ctgactggtg agtttgtcgc gttcaggaga gagtcggcgc agctctgcta attccgcatc
    22261 tttggcgttc agcaactggt catacgaagc cgcggccggt tggttctggc gatcccccaa
    22321 tttgctttca agatcgcgaa tacgatcgtg gaattccccg agagtcgtca ggagctgttc
    22381 gcgctcctgt tgaagggcta ggagtttggc atcgcctacc tggggtgggg ctgcgaccgg
    22441 ctgtggctga ggcacggtct cacaggccga agcaagggca ccgagaacca tgagcgccca
    22501 cacagctcgt ctcatacgat ctctccctgg tcatcggaac gactgccgaa catagcggag
    22561 ggggcgatag tcgtcacagg actgttcaga tgggcagcaa gcccagacga cggaggctga
    22621 tctggttgat gctgatcagc cggtgtgcgc actgcgtgcc tgacaaatcg ggtgacaacc
    22681 atgcaggccc caagaacacg ccgggtactc tagcgtgttc ttgggatgga cgcaaggcgt
    22741 acaacgcgca atgagagagg actactgtcc gaccacgatt tcgacacgcc ggtttttctg
    22801 ccgtccctcg gccgtagaat tgcttgcgat gggtcggctg tcggcatgac ctttggcgct
    22861 aatcttgtcg gccgccatac cgccttccgt caacgcctgg cgtgcgctct cggctcgcgc
    22921 ctgggagagc tcggcgttgg tcgggaaccg ctttgccaat cgtcccttga ttggcacgtt
    22981 gtccgtgtgg cctgccacat ggatggagcg atccggatag ttcttgagta cgctgccgat
    23041 acgattcaag acatccgctc cgcctggttt cagggtggcc tctccggagt cgaacagcaa
    23101 ggtcgtggct aaaccgaggg taagctgatc ccccagttgt ttcatcgtca cgttgccctt
    23161 ggatacctct gcctggagga gtttcgacaa atcgtttttc gcttcggcga gactggtctt
    23221 ttgttgatcg agtgctccac ggagaccggc catctcatgg tctcgccgtc cgatttcatt
    23281 ttcgaggtcc gatgctcgct gcttggcggc ggcgagatcc gccacgagcc tatcgcgatc
    23341 accggccgca cccttcagcg tccccagttc ctgatccttc ccactgagct gacgctccag
    23401 gtcggcaatg tgctgtttcg cctgtgccaa ttcggacgaa agacgatcac gatccccggc
    23461 attatgtttg agcccggcaa gctcctggtc cttcgtcgcg agcaaccctt gcaaggcggc
    23521 caactcggcg gccagccgtt ccttgtcagc ggcgctctgc ttcaacgccg ccagttcttg
    23581 atccttggcg gacaaccgtc ggtccgcgtc ggacaattgg ccggccaatc gatccttgtc
    23641 gcccgcggcg ttgcgaagcc cagccagttc gcggtcgcgc tgattcagtt ggttctccag
    23701 ttcggtgatc cgcgccttgg accgatctga gtcggcggcg cttgatgagc gcaggcgatc
    23761 caactcgcct tcgagatcgg ttttctggcg ttccagttct gcgatccgga gatcgcgcgg
    23821 atccggctta ggcgggatgg gcctggcgac ggccttcatc tcattcagcg ctcgactcgc
    23881 tgagtcattg ggtgccggtg tagatgtgca ggctgcgagc aatgcagcgc tcagcagcac
    23941 gggaacgacg caaacgtgtt tcatgcaatc ctccttacaa cacagtcaga ctgccggaat
    24001 gttcccagca gcactgggcg aacgccccat ggttagtgac gttgattctt caggagatca
    24061 cggatctcgg tcaacaagac ttcttccttt ggtggcgccg gtggggggcc gggaggcgtg
    24121 gccttcttaa agcgattcat ttgtttgacc actaaaaaga tcacgaaggc cagaatcgta
    24181 aaatcgagca gagtctgcag gaagacgcca taattaatcg tggcggcacc ggcggctttg
    24241 gccgcggcga gggatttgcc tttggcctct tcactcaacg gaataaagag actggagaag
    24301 tccatgtgtc ccatgaggag accgatgggc ggcatgagaa tatcactgac cacggatgac
    24361 acgattttcc cgaatgcccc tccgatgatg acccccacgg ccatgtcgag cacattccct
    24421 tttacggcaa attctttgaa ctcactcatc atgcccattg tgcaccctcc ttatgtgagt
    24481 cgaatcaatc ccgaaaccgt cccgcatctt attgttttcg actggtgtcg aa
//
LOCUS       DAOQPD010000056        24324 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_979_length_24324_cov_25.800074, whole genome shotgun sequence.
ACCESSION   DAOQPD010000056 DAOQPD010000000
VERSION     DAOQPD010000056.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 24324)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 24324)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24324
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_979_length_24324_cov_25.800074"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..435
                     /locus_tag="PK063_12840"
     CDS             <1..435
                     /locus_tag="PK063_12840"
                     /inference="COORDINATES: protein motif:HMM:NF024989.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HMZ97984.1"
                     /translation="KEFGADVVIDFTEQDPVEAILGLTGGQGVDSSIEALGAQATFEA
                     CIKATRPGGTISNVGYHGEGQYVQMPRKEWGVGMSDKVIRTGLCPGGAERMKRLMRLL
                     ETGRVNPLPLTTHRFRFSDVEKAFELMRTKADGMLKPLITFA"
     gene            687..1262
                     /locus_tag="PK063_12845"
     CDS             687..1262
                     /locus_tag="PK063_12845"
                     /inference="COORDINATES: protein motif:HMM:NF019845.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HMZ97985.1"
                     /translation="MYKTKAYSAASATSSLVSTTIARRDPTEHDVQIEILYCGICHSD
                     LHSVRNDWSSVMSTTYPIVPGHEIVGRVTKVGSAVTKYKPDDLAAVGCLVDSDGTCPN
                     CTAGLENFCPNQTFTFGSPDKHKTAPVTYGGYSDSIVVDERFVLRAPTNLNGAGTAPL
                     LCSALGSPPTHPCATTASPRVRKWASSAPVA"
     gene            1235..1753
                     /locus_tag="PK063_12850"
     CDS             1235..1753
                     /locus_tag="PK063_12850"
                     /inference="COORDINATES: protein motif:HMM:NF012335.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HMZ97986.1"
                     /translation="MGIVGPGGLGHMGVKFARVFGAHVVVFTTSPSKAEDALRLGAHE
                     VVVSRDANEMKKHTGSFDFILDTVPVDHDINQYLHLLRLDGNLTLVGVPSQPLALSSF
                     ALIFGRRSVSGSNIGGIPETQEMLDFCGEHNITADVEVIPIQNVNEAYDRLLKSDVKY
                     RFSIDMASLKTE"
     gene            1831..2715
                     /locus_tag="PK063_12855"
     CDS             1831..2715
                     /locus_tag="PK063_12855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016205472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HMZ97987.1"
                     /translation="MQTTTLSNGLHMPMLGLGVFQAPPDVTAAAVQEALRVGYRLIDT
                     AAAYANEREVGEGIRRSGLARDDIFIQTKVWISDYGYDATVHAFDKSAGKLGVDQLDL
                     LLLHQPLTSRFDLTLGAYKALEKLLADGKVRAIGVSNFMPDVLQRLLAETSVVPAVNQ
                     IEVHPYFQQKELQRLHAEHGILTQAWSPLGGITSYGGGEKRTFDDPTLQQIAREHGKS
                     AAQVMLRWHLQEGRSVIPKSTKPARIAENLDVFDFELTKEQVASIDALDTGVRSGPEP
                     DSITLENYGREIPEACGK"
     gene            2912..3712
                     /locus_tag="PK063_12860"
     CDS             2912..3712
                     /locus_tag="PK063_12860"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012334.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HMZ97988.1"
                     /translation="MSKTIFITGASSGLGKATAKLFAVKGWNVLATMRQPAKETELTQ
                     FANVTVLPLDVTRSEQVSETIQSALKSSDVDVVFNNAGYGLAGPMDGIDDARIVRQFE
                     TNVFGAMRVTREFIPYFKQKRSGRFITTTSLAGLIGLPLNSVYNASKWALEGWSEGLS
                     YELAPFGIKVKTVAPGAVMTDFMSRSLDHVPAPGYDAMNEATVKFFVPDMAKISSAES
                     IAQVVWEAATDDQDHLRYVAGDDAIDIYALRQKLGNESFRQHLASLVL"
     gene            3751..4464
                     /locus_tag="PK063_12865"
     CDS             3751..4464
                     /locus_tag="PK063_12865"
                     /inference="COORDINATES: protein motif:HMM:NF013989.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HMZ97989.1"
                     /translation="MKPQVICHMLSSVDGRLHVGRYTPLTSGKTSTEASAPYYEYSAK
                     FDADAQIIGGRTARESALPLRYEGDVATRPAHFQTFVGHRQSKRSLIVLDPQGTIRYD
                     SDNVSGENLIAVLGESVSQQYLDHLQAQGVSYLFAGPKGDDVPRLLGTLSADFGMTRV
                     LVEGGGTINGAFLKAGVIDELSLMLYPGIDGLAGIPSIFECQGAPGEKPAEGQSMELV
                     AVETLPDGIVWLRYRFHRQ"
     gene            4545..4829
                     /locus_tag="PK063_12870"
     CDS             4545..4829
                     /locus_tag="PK063_12870"
                     /inference="COORDINATES: protein motif:HMM:NF012472.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HMZ97990.1"
                     /translation="MKYIKLGNTGIDVSKICLGMMSFGKPGSEHGLFPWAVDFEDAKP
                     IFKKAIELGINYFDTANVYQLGTSEEVTGKLIKEFKLDRDDLVVASAAWA"
     gene            4820..5740
                     /locus_tag="PK063_12875"
     CDS             4820..5740
                     /locus_tag="PK063_12875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014448369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HMZ97991.1"
                     /translation="MGLSFGYGPATDKGDAVKLIRAAFERGVTFFDSAEAYGAVNEEM
                     VGEAVAPFRDKIIIATKFGFKDGNSQAGLDSTPARIRLVAEQSLKRLKTDRIDLFYQH
                     RVDPNVPMEDVAGVVKDLITEGKVKHFGMSEAGVAMIRRAHAVQPLTALQSEYSMFTR
                     EPETEIIPTLEELGIGFVPFSPLGKGFLTGKMDVDTKLDANDFRNTLPRFEAENRRAN
                     LAFVELLTTIANRKQVTPAQIALAWLLAQKSWIVPIPGTTKLHRLEENLGAASVDLTT
                     DDLREIEQGVSKLTVQGARYPEKVEQMTNR"
     gene            5860..7242
                     /locus_tag="PK063_12880"
     CDS             5860..7242
                     /locus_tag="PK063_12880"
                     /inference="COORDINATES: protein motif:HMM:NF012398.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HMZ97992.1"
                     /translation="MSYQSVNPFDGTTVKTFEQLTDAQLETALETAANCFENWRRTTF
                     AERGAIAAKAAAIMRARIDEFARPVTLEMGKLIAESRAEVQLSADIIDYYAKTAERFL
                     APEPLQPGSGEAKIESAPFGVLFGVQPWNFPYYQLARFAAPNLMAGNVVMVKHSGTVP
                     QCAIAFEKLWLEADAPAGAYTNLFISYEQVNRVIEDRRVKGVALTGSVDAGKSVAERA
                     GKHLKKTTMELGGSDAFIVLEDADLDKTVKWAVWAKMNNTGQCCIAAKRYIVVEKLAD
                     RFLEKFKSALSALTPGNPMDKATTLGPLSTEGALVNLLKQVDQAVAHGADLVLGGKRM
                     DRPGAFMEPTILTNIKPDNPAYREEFFGPVALMFRVKNEDEAVVLANDSDFGLGGSIF
                     TNDVARGKRVASRINTGMVFINHPTWTAPDLPFGGIMDSGYGRELSSMGIQEFVNKKL
                     VRVESIDAPA"
     gene            7638..8633
                     /locus_tag="PK063_12885"
     CDS             7638..8633
                     /locus_tag="PK063_12885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014961581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HMZ97993.1"
                     /translation="MQTRKLGNSGLEVSALGLGCMGLTSFYNTALPEGEAVAFLRAAY
                     EKGITLFDTAEAYGPFVNETIVGKAVAPFRDKVVIATKFGFDIDLETGRHLGGVNSKP
                     AHIRAVVDASLKRLATDRIDLLYQHRVDPEVPMEDVAGAVRDLIAAGKVKHFGLSEAG
                     PESIRRAHAVQPVTALESEYSLWHRGPEEKILPLCQELGIGFMPFSPLGAGFLTGKIQ
                     ADTRFGESDYRNTEPRFAQENREANMALVALVKDAAARKGATPAQVALAWLLAKKPWI
                     VPIPGTTKLHRLEENIGAVDVVLSADDIAEMETTLAGLTLRGERLSAGELAMTGL"
     gene            8641..9081
                     /locus_tag="PK063_12890"
     CDS             8641..9081
                     /locus_tag="PK063_12890"
                     /inference="COORDINATES: protein motif:HMM:NF015411.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="HMZ97994.1"
                     /translation="MTQTIGIIGSGMIGGQVARLAIAAGFNVVICNSRGPETLAELVS
                     KQGPSARAATFAEVTEAADLIVLAVPFAGYAKLSAEALAGKTVIDTMNYYPERDGVMP
                     EVKTDTIATSELVQKHLSRSRVVRALNNMDFVRLLSRARPKGSA"
     gene            9211..9396
                     /locus_tag="PK063_12895"
     CDS             9211..9396
                     /locus_tag="PK063_12895"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ97995.1"
                     /translation="MPVYVNPYWDLDDSHAVSSFMVAPGRVVTRQEVAALLGKAIRHD
                     KMFGLLGAFDVRTNRLS"
     gene            9693..10757
                     /locus_tag="PK063_12900"
     CDS             9693..10757
                     /locus_tag="PK063_12900"
                     /inference="COORDINATES: protein motif:HMM:NF012472.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HMZ97996.1"
                     /translation="MKTPLLKLNNGVEMPALGLGVFQSSPEDTIKAVATAIADGYRLI
                     DTARAYKNESQVGEGIRNSGINRAELFVTTKLWLTDYGYDAALRGFDGSLTKLRLDYL
                     DLYLLHWPTKNFDATVQSYKAAEKLLAAGRVRAIGVCNHTEQQLEALIARTDVVPAVN
                     QVELHPYFAQKALRQTSAALGIVMQAWSPIGGVKRYWPGASATGTGDPLADPVITGIG
                     RAHGKTAAQVILRWQFQNGVVAIPKSVKAARIAKNIDIFDFVLSDSEMTKIDALDTGA
                     RGGPDPTQIDMDSFSDTVDRMHPVRVSRRDAKQTEPLNEHRSIRHSCSYHGCRLRNGV
                     GISRGILGSRRVRRAVRKPQ"
     gene            10793..11050
                     /locus_tag="PK063_12905"
     CDS             10793..11050
                     /locus_tag="PK063_12905"
                     /inference="COORDINATES: protein motif:HMM:NF014479.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="muconolactone Delta-isomerase family protein"
                     /protein_id="HMZ97997.1"
                     /translation="MNRVLVITYPKKDDRIASVMAAEYAMTNSWRDQGIIEHLFAKEN
                     DGGGVVVFNETSVEKVQALIAQLPLFPFFEKVEYFPLNKIY"
     gene            11089..11991
                     /locus_tag="PK063_12910"
     CDS             11089..11991
                     /locus_tag="PK063_12910"
                     /inference="COORDINATES: protein motif:HMM:NF023568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HMZ97998.1"
                     /translation="MQRVSFKNRNIIMAGSLCQPRDFKDGARYPAVVVVHPAGGVKEQ
                     TAGEYAKRLAAEGFVTLAFDTSYQGESGGEPRYLDEPMNRVGDIYSAVDYLTTLPFVD
                     AERIGILGICAGGGYSVKAASLDRRIKAVATASAANVGNAARKGWDGKSPMSALPGTL
                     EMLVNQRTAEAAGAAIAYAPYVPNVGESSPFRDLREGSDYYLTPRGRHPNAPNKMLMT
                     SLMGWIAFDAFDLVDPLLTQPLMICAGSEADSLWQSQELYAKAPGSSKELFIIERASH
                     MGLYDGSGREAVLGKITPFFRANL"
     gene            12005..12601
                     /locus_tag="PK063_12915"
     CDS             12005..12601
                     /locus_tag="PK063_12915"
                     /inference="COORDINATES: protein motif:HMM:NF012472.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HMZ97999.1"
                     /translation="MSASTPMTSSATSAGQLLARQRRHASPELLAAALLLLGTVAALQ
                     SEYSLWWREPEQELLPTLEELSIGFVPFSPLGKGYLTGKIDETTTFDSTDFRNTVPRF
                     TAENRKANQAMVELLGRIAERKKATPAQVAIAWLLSQKPWIVPIPGTTKLHRLEENVG
                     GAAVELTPDDLRDIADAAANIAVHGERYSEAAQKMINR"
     gene            12715..13833
                     /locus_tag="PK063_12920"
     CDS             12715..13833
                     /locus_tag="PK063_12920"
                     /inference="COORDINATES: protein motif:HMM:NF012472.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HMZ98000.1"
                     /translation="MKYRKLGNTGTVVSTLALGTMYFGDETAENDAFAILDAFLDAGG
                     NLVDTSDVYVGTVAEQIVGRWLAARPREITDRVIVATKGRFGDDSDPNAVGLSRRHLH
                     RALDASLRRLDVETIDLYQLHASDMHTPVEETLSFLDDAVRAGKIHYVGLSNFTGWQL
                     QLMVSTAKATGVQTLVSLQQQYSLLSRECEWEMNPAARHNGLSLLPWSPLAGGFLTGK
                     YQRGGTPASDSRAGSGKDLYQWISADYAGSDQNWATIETVIRIAKEIGATPAQVALSW
                     IANRPGVAAPIFGARNLRQLDENLAAAKLTLDENATKALEVVSAPRSNGYPYGAFGAG
                     QRNRDLRDGNPAPGLPVAGGSDHPLGRPSLTVTSRVSD"
     gene            13858..14304
                     /locus_tag="PK063_12925"
     CDS             13858..14304
                     /locus_tag="PK063_12925"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98001.1"
                     /translation="MDRPRIFIHMHMSLDGKIVGSYLPTDVGMASQRQYYNLFLGPDR
                     HFRNHKGWLSGRTTSEDNFTHYRKLKLDEFAPPMPEGDFIAVDDAPMHYFSVDPSGVL
                     AWETNSITYFDTTAHVVQILSGKATNAYKDFLRRKGVSYTSPARTL"
     gene            14328..14591
                     /locus_tag="PK063_12930"
     CDS             14328..14591
                     /locus_tag="PK063_12930"
                     /inference="COORDINATES: protein motif:HMM:NF013989.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HMZ98002.1"
                     /translation="MGSAFGVDEIMLCGGGGLNWSFIRADLCDEVSIVLTPAADGTKG
                     AQTLFEADERYTQPLPTAFKLKEVQPLDDGSVWLRYTVEGPIN"
     gene            14761..15849
                     /locus_tag="PK063_12935"
     CDS             14761..15849
                     /locus_tag="PK063_12935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014961581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HMZ98003.1"
                     /translation="MCITPALGKPAAGPAPICDQNRTSSPLITQRRTLGSGKHALQVS
                     ALGFGCMGMNYHRGLHPDRDAMIKLARQATERGVTLFDTAEVYGPFVNEELVGEALAP
                     FRGQVVITTKFGWKIDPGSRTSIGLDSRPQHIKEVAEASLKRLKVDAIDLFYQHRVDP
                     DVPIEDVAGAVKELIQEGKVKHFGLSEAGAKTIRRAHAVQPVTAVQSEYHLMWRAPEK
                     DVLPVCGELGIGFVPYSPVNRGFLGGNLNEYTRFDSGSDNRKTLPRFTPEAMRANLAI
                     VEALNRFGRTRGVTSAQVALAWLLAKQPWIVPIPGTTKLAHLEENLRTADLKLSAAEM
                     SEIEGSVSKIEIVGDRYPAEQQKLVSPD"
     gene            16073..16483
                     /locus_tag="PK063_12940"
     CDS             16073..16483
                     /locus_tag="PK063_12940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004099044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HMZ98004.1"
                     /translation="MNKPEFFVTPGYGERNLKLFHYSQAVKIGNRLELSGQGGWNDDW
                     EFPESITDEIAQAFRNVERTLAVAGARWEYVIHVNSYHVGLDGDQEEINQAMTERFRH
                     YMPGHAPVWTCLGVAALGDPKMRVEIRVTAILPE"
     gene            16622..17638
                     /locus_tag="PK063_12945"
     CDS             16622..17638
                     /locus_tag="PK063_12945"
                     /inference="COORDINATES: protein motif:HMM:NF012335.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HMZ98005.1"
                     /translation="MRGAVLYGPRDVRFEERDAPKIIEPTDAIIRIALTCVCGSDLWP
                     YRGLQPITEPTPMGHEYCGIVEEIGGAVRSVKPGQFVIGSFATSDNTCPHCQAGYQSS
                     CVHREWMLRAQAPVLRVPLADGTLVPTPGVPSNDLLPSLLTASDVLGTGWFAADAANV
                     TPGSTVVVVGDGAVGLLGVLSAKQMGAERIIAMSRHEKRQQLAREFGATDIVTERGDE
                     GTTQIKELTNGVGADSVLECVGTQESMMQAILATRPGGSVGYVGVPHGVLLDGEKLFY
                     SHVHLHGGPAPVRRYLPKLIDLVLDRKINPGKVFDLTLPLDQVAEGYRAMDERRAIKA
                     LLRP"
     gene            17699..17974
                     /locus_tag="PK063_12950"
     CDS             17699..17974
                     /locus_tag="PK063_12950"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98006.1"
                     /translation="MPRPSRPGATLEKQQPHLHDEARHIWESYKKGVIRDISFRQDRL
                     GVATTLERNCAGSLKPMPCTFRNDVEKAFELMRTKADGMLKPLITSA"
     gene            18143..20563
                     /locus_tag="PK063_12955"
     CDS             18143..20563
                     /locus_tag="PK063_12955"
                     /inference="COORDINATES: protein motif:HMM:NF016292.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate binding protein"
                     /protein_id="HMZ98007.1"
                     /translation="MHTKTFFCIISVIFLLSWRSNVEAKSLPVVQVGIVRDGPSELVP
                     ELRDLIQKEILEITRGEFEVRFPNDLQFDGGWSVQGVKQAIDRVLAQPRVNLVIALGI
                     LASQEVSQRRQLPKPVIAPLILDPHLQGLPFKKGTSGMKNLSYLVTGKGFERDLEAFK
                     EVFPFTRLTLLADRVLLEAFPPVKDRARKMAETYGVKLTVVPVETSAEAAIGSIPPDT
                     EAVYLSPLPRLLAGEFDRLVLALNRRKLPSFSAVGQRDVQRGITLALSPELDLGRFAR
                     TIAANVQRILSGTDAGRLEVAFIRGEQLVINMATVRAIDKWPSFQVLSEAELVNEDAA
                     GTSRRLSLFEAVRESAEANLDLAAASRKVAAGVGQVGQARSGLLPQVLVGTSGVLNGR
                     GPDTFGTGGTPGQAAIALGGFRQLLYSDDAWTKYTVQQKTQLSREEEWNQLRLDIAQD
                     AALAYLTVLRTKTVRRIQKDNLKLTRANLDMAAARESVGYALRDELFRWEAEVANGQK
                     AVVSAEAQERQAEVDLNRILNRPLEERFQTVEQTLEDPGLLGDTRQLFAYIENPRGFQ
                     VFRDFEVEEGIQAAPELRRLDALSAAQERTITNAQRAYWLPEVAIQGAGFQQYAQGGG
                     GAGSLTVPLGPVGFAQTQNNFYVASIGLTFPLFQGGYKDATALKAREELRQVQFERAA
                     VALQVEERVRTTLYQTGASFPSIRLSRKAAESARKTLDLVVDQYSRGAVDIIKLLNSQ
                     NAALTANQAAANAVYEFLIDLAKVQRAVGQMSFFRSSEERAAWFERLKTHFVNAGVSP
                     VLRDDPRN"
     gene            20582..21574
                     /locus_tag="PK063_12960"
     CDS             20582..21574
                     /locus_tag="PK063_12960"
                     /inference="COORDINATES: protein motif:HMM:NF027890.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HMZ98008.1"
                     /translation="MPTPKIARPTLILGVGLLLLVAGASVWWFYFRIPPLVGFGSGNG
                     RLEVQEIDVATKFPGRIAEVLVDEGDSVQVGQVVARMDTSSLNAQVREAEAQVQRAKQ
                     GKITAKAVIAQRRSETLLAERDLERARALYVNANISVKDYDRARSTMDTAKSAITQAE
                     AQLAEAEAAIKASLAQSERIQADLKESVLTAPRSGRVQFRLAEPGEVLAAGGKVLTLI
                     DPTDVYMTVFLPAAEAGKIALGAQARITLDAAPNLVIPSAVSFVADKAQFTPKEVETR
                     TEREKLMFRIKVKIDPELVKGHEAQVKPGLPGVAYVQLDSSVQWPPSLQTKLIR"
     gene            21571..24318
                     /gene="rbbA"
                     /locus_tag="PK063_12965"
     CDS             21571..24318
                     /gene="rbbA"
                     /locus_tag="PK063_12965"
                     /inference="COORDINATES: protein motif:HMM:NF033858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated ATPase/putative transporter
                     RbbA"
                     /protein_id="HMZ98009.1"
                     /translation="MSEPSASVARVATLTHRYGDTTALDAVTLDIPGGRMVGFIGPDG
                     VGKSSLLALIAGAKKIQAGQVEVLGGDMAAVRHRNEIYPRIAYMPQGLGGNLYLTLSV
                     FENVDFFGRLFGQNREEREWRITDLLRSTGLTPFRDRPAGKLSGGMKQKLGLCCSLIH
                     DPDLLILDEPTTGVDPLSRRQFWDLVDRIRKRRAGMSVLVATAYMEEAERFDWLVAMD
                     AGKVLATGSPAELKGRMNVRTLEDAFVSLLPEEKRRGHSAIAIPPRRTHEGPPAIEAH
                     GLTMRFGSFTAVDHVSFRIERGEIFGFLGSNGCGKTTTMKMLTGLLPASEGDARLFDR
                     PVNAQDMETRKRVGFMSQAFSLYGELTVRQNLELHARLFHLQPEKIPGRVAELTKRFK
                     LEDYLDDLAEALPLGIRQRLSLAVAVVHQPEILILDEPTSGVDPVARDGFWELLIELS
                     RKDRVTIFISTHFMNEGERCDRISLMHAGRVLVSDTPEGLIRTRGAANLEEAFIGYLE
                     EASGEATQKEVVEEAAETMPSASGTSRADRGRAFSPMRLFAYAHREALELRRDPIRLT
                     FALLGSVLLMFILGYGITMDVEDLRFAALDRDRTPQSRDYIQNLAGSRYFIERPFITD
                     DAELDRRMRSAELSVAIEIPSGFGRDLKRGRQTEVGVWVDGASPFRGETIKGYVQGMH
                     YQYLADLARRTYGAQPQTGLADLEMRYRYNQDFKSLESMVPAVIPLLLVFIPALMTAL
                     GVVREKELGSITNLYVTPVTRLEFLLGKQLPYIVLSMISFFGLVALAVVAFKVPLKGS
                     FATLALGGVVYVIVTTGIGLLMSAFTRSQIGAVAGTAILTMLPTVQFSGLTDPVSSLE
                     GIGALIGQVWPATYFLVISRGTFTKGLDFWDLYGYLIALAVFIPVLTLLSLALLKKQG
                     T"
BASE COUNT         5188 a         7204 c         7373 g         4559 t
ORIGIN      
        1 aaagagttcg gggcggatgt ggtgatcgac ttcacggaac aggatcccgt cgaagccatt
       61 ctcggcttga cgggcggaca aggcgtggat tcgtccatcg aagccctcgg ggctcaggcg
      121 acgttcgaag cctgtatcaa agcgacgcgt ccgggcggga ccatttccaa cgtgggctat
      181 cacggagagg gacaatacgt acagatgccg cgcaaagaat ggggcgttgg gatgagcgat
      241 aaggttatca ggacgggact ctgccccggt ggagcggaac ggatgaaacg gctgatgcgg
      301 cttttagaaa ccgggcgtgt caatccgctc ccactgacga cgcatcgatt cagattcagc
      361 gatgtggaga aggcctttga gctgatgcga acgaaggcag acggcatgtt gaagccgctc
      421 atcacgtttg cgtgaaggga agctcccaac tcttttggcg tgccctgcaa gaaaattggc
      481 gcgccgtgct agtgatcgat ccgggtaaag atcctacttc gtcggataaa tgaataatcc
      541 attcgacttc aaggccgtcg actaatgtaa aaggtccgcg acgagcaata tcaggccgga
      601 ttaaaggtcg aataaatgga aacagccatc gggtctggtt tatcagaccg tataccgaca
      661 tcttttgcct agaggaggat atatccatgt acaagacgaa ggcttactcc gctgccagtg
      721 cgacatcgtc gcttgtctct acgacaatcg ctcgtcgaga tccaaccgaa catgacgtac
      781 agattgagat actgtactgc ggcatctgtc actccgacct ccattcggta cgtaacgatt
      841 ggagcagcgt catgtccact acctacccga ttgtcccagg tcatgagatc gtcggccgtg
      901 tcaccaaggt cggctcagcg gtgacgaagt acaagcccga cgaccttgcc gcggtcggct
      961 gcctggttga ctcggacggg acttgcccga actgtacagc cgggcttgag aacttctgcc
     1021 cgaaccagac cttcacgttc ggctcaccgg acaagcacaa gaccgccccg gtcacctacg
     1081 gcggctactc cgacagcatc gtcgtcgacg agcgcttcgt cctccgcgcc cccaccaacc
     1141 tcaacggcgc cggcaccgca cctctgctct gctctgcgct gggatcacca cctactcacc
     1201 cctgcgccac cacggcgtca ccaagggtaa gaaagtgggc atcgtcggcc ccggtggctt
     1261 aggccatatg ggggtgaagt tcgctcgggt gttcggggcc cacgtggtgg ttttcaccac
     1321 ctcgcccagt aaggcagaag atgcgctgcg cctgggcgcg cacgaggtcg tcgtatcccg
     1381 tgatgcgaac gagatgaaaa agcacaccgg cagctttgac ttcattctcg acacggttcc
     1441 cgtcgatcac gacatcaacc aatatcttca tctcctccgc ctcgacggga acctgaccct
     1501 cgtcggagtg ccgtctcaac ccctcgcgct gtcgtcgttc gcgttgatct ttgggcgccg
     1561 cagtgtgtcc gggtcgaaca tcggtggtat ccccgagacc caggagatgc tcgacttctg
     1621 cggcgaacat aacattaccg ccgatgtcga agtcatcccg atccagaatg tcaacgaagc
     1681 ctatgacaga ctgctgaagt ccgatgtgaa gtaccggttc tccatcgaca tggcgtctct
     1741 caagactgag tgaccgaccc gatactcgaa aggaaaaaca aatgcaaaaa ggacaataag
     1801 gtgtcagcaa cctttgagga ggctatatcc atgcaaacga ccactttgag caacggcctg
     1861 cacatgccga tgctagggct aggggtgttt caggccccgc ccgatgtcac ggctgccgcc
     1921 gtccaagaag ccttgcgggt gggctatcgc ctcatcgaca cggccgccgc ctacgccaac
     1981 gagcgcgaag tgggcgaagg catccgccgt tcgggactcg cccgcgacga catcttcatt
     2041 cagacgaagg tgtggatcag cgactacggc tacgacgcca ccgtgcatgc gttcgacaag
     2101 agcgccggca agttgggggt cgatcaactc gacctgctgc tcttgcatca accgctcacc
     2161 agccgtttcg atctcaccct cggcgcttac aaggcactgg agaaactgct ggccgacggc
     2221 aaggtgcgtg cgatcggcgt gagcaacttc atgccggacg tgctgcaacg ccttctggca
     2281 gaaacatcgg tggtgcctgc ggtgaaccag atcgaggttc atccctactt ccagcaaaag
     2341 gaactgcaac gtctccacgc cgagcacggc atcctgaccc aggcctggtc gcccctcggc
     2401 ggcatcacgt cctacggggg cggcgagaag aggacgttcg acgaccccac cctgcagcag
     2461 attgcgcgtg agcatggcaa gtcagccgcg caagtgatgc tgcgttggca cctgcaggag
     2521 ggccgttcag tgatccccaa atcgaccaag cccgcgcgca tcgccgagaa ccttgacgtg
     2581 ttcgacttcg aactcaccaa ggagcaggtc gcttcaatcg acgcgctcga tacaggcgtg
     2641 cgcagcggcc cggagccgga cagcatcacc ttggagaact acggtcgcga gattccagag
     2701 gcctgtggaa aataaagtgt caggaacctt ttattggctc aacatgcggc aagaccagaa
     2761 atggttcctg acacctttcc accccgccgc tgctgatccc ccgcatcgga gaagttgccg
     2821 agatcgggag cgccgctcag acattccctc gctggtggga agacgtctca ccttgatctg
     2881 ccttgtgacg acttgaaagg agctatcaac catgagcaag accattttca ttaccggcgc
     2941 atcttcgggg ctgggcaaag ccacggccaa actgttcgcg gtcaagggct ggaatgtgtt
     3001 ggcaacaatg cgtcagcccg ccaaggaaac cgagctgacc cagttcgcca acgtcaccgt
     3061 gctgccgctg gacgtgacgc gctcggaaca ggtgagcgaa acgatccaaa gcgcgctgaa
     3121 gtccagcgac gtggacgtgg tgttcaacaa cgcgggctac ggtctggcag gcccgatgga
     3181 cggtattgac gatgcccgca tcgtgcggca gttcgagacc aacgtcttcg gtgcgatgcg
     3241 cgtcacgcgc gagttcatcc cgtacttcaa gcaaaagcgc agcgggcgct tcatcaccac
     3301 cacatcgctg gcgggcttga tcgggctgcc gctcaactcg gtctacaacg ccagcaaatg
     3361 ggcgctggaa ggctggagcg aagggctgtc ttacgagctg gccccgttcg gcatcaaggt
     3421 caagaccgtc gcgcccggcg ccgtcatgac cgacttcatg agccgctcgc tcgaccacgt
     3481 gcccgcgcca ggctatgacg ccatgaacga ggccacggtg aagttcttcg tgcccgacat
     3541 ggcgaagatt tccagcgccg aatccatcgc gcaagtagtc tgggaagcgg ccaccgatga
     3601 ccaggatcac ctgcgctacg tcgccggcga tgacgccatc gacatctatg cgctgcgcca
     3661 gaagctcggc aacgaaagct ttcgccaaca cctcgccagc ctggtgcttt gaggctgccc
     3721 attcaccgtc aagaaagcga gatacacaag atgaagcccc aagtcatttg ccacatgctg
     3781 agttccgtgg atggccgctt gcacgtgggc cgctacacgc cgctgaccag cggaaagacc
     3841 tccaccgagg catcggcccc gtactacgaa tacagcgcga agtttgatgc ggatgcgcag
     3901 atcatcggtg gacggacggc ccgcgaatcg gcgctgcccc tgcggtacga gggcgatgtc
     3961 gctacgcgac ccgcgcattt ccagaccttc gtgggtcatc ggcaatcgaa gcgatccctg
     4021 atcgtgctcg accctcaggg aacgatccgc tacgacagtg acaacgtgtc cggtgaaaac
     4081 ctgatcgctg tcctgggcga aagcgtctcg cagcagtatc tggaccatct gcaagcgcaa
     4141 ggcgtgtcct atttgtttgc cggccccaag ggcgacgacg ttcccaggct cctgggcacg
     4201 ctatcggcgg acttcggcat gacccgggtg ctggtcgaag gcggcggaac catcaacggc
     4261 gccttcctca aggccggggt gatcgacgaa ctgagcctga tgctttatcc cggcatcgac
     4321 gggttggcgg ggattccgtc gatctttgaa tgccaagggg cgccgggcga gaagccggcc
     4381 gaggggcagt cgatggagct ggtggccgtc gagactttgc cagacggcat tgtctggctg
     4441 cgctatcgct ttcatcggca atgacgcccc ccacacattg aggttgcgct atgcctatca
     4501 cctttctatt ggttcggcga cctccataga ggaaagagaa aaccatgaag tacatcaaac
     4561 ttggaaacac aggcattgac gtctcgaaga tttgcctcgg gatgatgagt ttcggcaaac
     4621 cgggcagtga acacggcctg ttcccctggg ccgtggactt cgaggatgcc aagcccatct
     4681 tcaagaaggc gatcgaactg ggcatcaact acttcgacac ggccaacgtg taccagctag
     4741 gcaccagcga agaggtgacc ggcaaactca tcaaggaatt caagctcgac cgggacgacc
     4801 tcgtcgtggc ctcggctgca tgggcctgag cttcggctac ggtcctgcga ccgacaaggg
     4861 ggatgccgtc aagctcatcc gcgccgcgtt cgaacgcggc gtcacgttct tcgactcggc
     4921 cgaggcctac ggcgcggtca acgaagagat ggtgggcgag gccgtcgcgc cctttcgcga
     4981 caagatcatc atcgccacca agttcggctt caaggatggc aattcgcagg ccgggctgga
     5041 cagcacgcct gcacgcatcc gcctcgtggc cgagcagtcc ctgaagcggc tcaagacgga
     5101 ccgcatcgac ctgttctacc agcaccgggt cgatccgaac gtcccgatgg aagacgtcgc
     5161 cggtgtggtc aaagacctga tcacagaagg caaagtcaag cacttcggca tgtcggaagc
     5221 cggcgtcgcg atgatccgcc gcgcccatgc cgtgcagccg ctgaccgcgc tgcagagcga
     5281 atactcgatg ttcacccgcg aacccgagac ggagatcatc cccacgttgg aagaactggg
     5341 catcggcttc gtgccgttca gcccgctggg gaaagggttc ctgacaggca agatggacgt
     5401 ggacacgaag ctggacgcca acgacttccg caacacgctg ccccggttcg aagccgagaa
     5461 tcgtcgcgca aatctggcgt tcgtggaatt gctcacaacc atcgcgaatc ggaagcaggt
     5521 cacccccgcg caaatcgcgc tcgcgtggct gctggcgcaa aagtcgtgga ttgtgccgat
     5581 ccccggcacg accaaactgc accgactgga agaaaacctc ggcgccgcgt cggtcgattt
     5641 gaccaccgac gacctgcgcg agatcgagca aggcgtctcg aagctgaccg tccagggcgc
     5701 gcgttatccc gaaaaggtcg aacagatgac caaccggtga acgctcgcgc cacaacagca
     5761 tgagccgtgc accagctcat gaacgcttgg accgccggct caccccggca cgaagccgtg
     5821 atggagtgac cacattaatc ttaaagaaag gatcacatca tgagctacca aagtgtaaat
     5881 cccttcgacg gaacaaccgt caagacgttt gagcaactga cagatgcgca gctcgaaacg
     5941 gcgcttgaaa ccgccgcaaa ctgtttcgag aactggcggc gcaccacctt cgccgagcgt
     6001 ggagccatcg cggcaaaagc cgccgccatc atgcgggcgc gcatcgacga attcgcccgc
     6061 cctgtgacgc tcgagatggg aaagctcatc gccgaatccc gtgccgaagt gcagttaagc
     6121 gcggacatca tcgactacta cgccaagacc gccgagcgtt ttctcgcccc cgagcctctt
     6181 cagcccggtt cgggcgaagc caaaatcgaa agcgctccgt tcggcgtgct ctttggtgtc
     6241 cagccctgga attttcccta ctatcaactc gcgcgctttg ccgcgccgaa tctgatggcc
     6301 ggcaacgtcg tgatggtgaa gcactcgggc accgtgccgc agtgcgccat cgcctttgaa
     6361 aagttatggc ttgaagcaga cgcgcccgcg ggcgcttaca ccaacctgtt tatttcctat
     6421 gaacaggtga atcgggtgat cgaggatcgc cgcgtcaagg gagtggcgtt gaccggcagt
     6481 gtggacgccg gcaagagtgt ggccgagaga gccggaaaac acctcaaaaa aacaaccatg
     6541 gagttgggcg ggagcgacgc cttcatcgtg ctggaagacg cagatctgga caaaaccgtg
     6601 aagtgggcgg tctgggccaa aatgaacaac accggccaat gctgcatcgc cgcaaaacgt
     6661 tacattgtcg tcgagaaact tgccgaccgt tttttggaaa aattcaagtc cgcgctctcg
     6721 gccttgacac ccggaaaccc gatggacaag gcgacgacgc tcggtccact ctctacggaa
     6781 ggggcactgg ttaacttgct caagcaggtc gatcaagccg tcgcgcatgg ggccgacctc
     6841 gtcctgggcg gcaaacggat ggatcggccc ggcgcgttta tggagccgac gatcctgacc
     6901 aacatcaagc ccgacaatcc cgcttaccgg gaggaattct tcggccctgt cgcattgatg
     6961 ttccgggtca aaaacgaaga cgaagcagtg gtgctcgcca atgactcgga cttcggtttg
     7021 ggaggatcga tttttaccaa cgacgtggct cgaggtaaac gcgtggccag ccgcattaac
     7081 accggcatgg tcttcatcaa tcaccccacc tggacggccc cggacctgcc ctttggcggc
     7141 atcatggatt ccggttatgg gcgcgagctt tccagcatgg gcatccagga gttcgtgaac
     7201 aaaaagctgg tgcgcgtgga atccatcgac gccccggcat aggaagcatt attcatgaag
     7261 gttcgtgacg aaacggcgga gacgccatgc gagacagggc gtggagcccc acgaggtcga
     7321 gacgtacttg acacagtaca tagggagacc gcgcggggcg agcccgcctg cctggccgcg
     7381 taacagccac ggccagactt gtcggagcga cgcatgcgct gtagcgaatc aagatcgatg
     7441 attcggaccg cgtcaagatg gttgatgggg attttaatga gtcctgagcc taggccatcg
     7501 gagtttgcaa tttgctcgtg gctcaaaccc cttcgagcaa acggttcccc gaccgatgaa
     7561 cgattttgag ataggttcta accacgggat ggttacaaaa cggtgcaatg acggcaacct
     7621 taagaaagga tcacatcatg caaacacgaa aactcggaaa cagcggcttg gaagtctccg
     7681 ccctcggtct cggctgcatg gggctgactt cgttctacaa cacggcgttg ccggaaggcg
     7741 aagccgtcgc cttcctgcgt gcggcctatg agaaagggat tactctcttc gacacagcgg
     7801 aggcgtatgg tcctttcgtc aacgaaacca tcgtcggcaa ggcggtggcg ccctttcgcg
     7861 acaaggtcgt gatcgccacg aagttcggct tcgatatcga tctggaaacc ggccggcatc
     7921 ttggcggtgt caacagcaaa cccgcccata ttcgcgccgt cgtcgacgcc tccctcaaac
     7981 gtctggcgac ggaccgcatt gatcttctct atcagcaccg ggtcgatccc gaggtgccga
     8041 tggaagacgt ggcgggcgca gtcagggacc tcatcgccgc agggaaagtg aagcatttcg
     8101 gcctttccga agccggtccc gaaagcatcc gccgggcgca cgcggttcag ccggtcaccg
     8161 cgcttgaaag cgagtattcg ctctggcatc gcggacctga ggaaaagatt ctcccgctct
     8221 gccaggaact gggaatcggt ttcatgccct tcagtccgct gggcgcgggc tttctcaccg
     8281 gcaagattca agctgatacc aggttcggcg agtcggacta tcgcaacacg gaaccgcgct
     8341 ttgcgcagga aaaccgcgag gccaatatgg ctctcgtcgc tttggtgaag gatgcggccg
     8401 cacgcaaggg cgcaacgccc gctcaggtgg ccctggcttg gctactggcg aagaagccgt
     8461 ggatcgtccc cattccaggc accacgaaac tgcatcgcct ggaagaaaat attggtgcgg
     8521 tggatgttgt tctcagcgcg gacgacatcg ccgagatgga aacgacgctt gccgggctta
     8581 ccttgagagg cgaacggctg tcggcaggag agttggcgat gacggggctg taggagcaat
     8641 atgacacaaa ccattggaat catcggcagc ggaatgatcg gcggccaggt agcccgcctc
     8701 gcaatcgccg caggcttcaa cgtcgtgatc tgcaactccc gcggaccaga gacacttgcc
     8761 gagcttgtct ctaagcaagg gccaagcgcc cgggccgcta cctttgcgga ggtgacggag
     8821 gcagccgatc tcatcgtgct cgccgttccc ttcgccgggt acgccaagct ttccgccgaa
     8881 gcgttggcgg gaaaaaccgt catcgataca atgaactact atccggaacg tgatggcgtg
     8941 atgccggagg tcaagaccga cacaatcgcc acaagcgagc tcgtgcaaaa gcacctgtcc
     9001 cgctcgcggg tcgttcgtgc attgaacaat atggactttg ttcgtttgct gagccgcgct
     9061 cggccaaagg gctcggcgta gcgcagtgcg ctgccggtct ccagtgacca tgctgaagct
     9121 aaggcagtcg taatcgattt tctcgataag attggctacg acgccgtgga catggggccg
     9181 ctgtccgaaa gctggcgcag cgagccgacc atgcctgtct acgtaaatcc ttattgggac
     9241 ctggacgact ctcacgccgt cagctccttc atggttgctc caggacgcgt cgtgacccgg
     9301 caggaagttg ccgcgcttct cgggaaggcc atccgtcacg acaagatgtt cggcttgctt
     9361 ggggcctttg acgtgagaac caacaggttg tcgtgatgaa tgttcaaaaa tccgcgtagg
     9421 ctcactttat ctttattatg aaacgacaaa tggcccgcta tgttctgatc gtgctttcga
     9481 acccgacgga cgggaaagag gaagagtaca agtcatcccg atccagaagg tcaacgaagc
     9541 ctacgacaga ctgctgaagt ccgatgtgaa gtaccggttc tcgatcgaca tggcgtcgct
     9601 caaatccgag tcaccggcgt ctcgcgtggg ataaaccatg caaaagcata aattgagaaa
     9661 gcaacctgga aacgataaga aaggagattg ccatgaaaac accgcttctg aaactcaaca
     9721 acggcgtcga gatgccggcg cttggcttgg gcgtctttca atcctcgcct gaggacacga
     9781 tcaaggccgt cgcgaccgcc atcgcggatg gctatcgatt gatcgacaca gcccgcgcct
     9841 acaagaacga gagccaagtc ggcgaaggca tccgcaacag cggcatcaac cgggcggaac
     9901 tcttcgtcac gaccaagttg tggctgacgg actacggcta cgatgcggcg ctgcgcggtt
     9961 tcgacggaag cctgacgaaa ctcaggctgg actatctcga cctttacctg ttgcactggc
    10021 caacgaagaa ttttgacgca accgtgcagt cctataaggc tgccgagaag ctgctggccg
    10081 cgggacgggt acgggcgatc ggtgtgtgca atcacacgga gcagcagctc gaagcgctga
    10141 tcgcgcgcac cgatgtcgtt ccagcggtca accaagtcga actccatccg tactttgccc
    10201 agaaggcgct tcgacagaca agcgcggcgc tcgggatcgt gatgcaggcg tggtcgccga
    10261 tcggcggggt gaaacgctac tggccgggag cgtccgccac cggcaccggc gatccgcttg
    10321 cggatcccgt catcaccggt atcggccggg cgcatgggaa aacggcggcg caggtcattt
    10381 tgcgctggca gttccagaat ggcgtcgtcg ccatccctaa gtcggtcaaa gctgccagga
    10441 tcgccaaaaa catcgacatt ttcgacttcg tgttgagcga ctcggagatg acgaagatcg
    10501 acgcgctcga taccggtgcg cgcggcggcc ccgatccgac gcaaatcgat atggacagct
    10561 tctctgatac agttgaccgg atgcacccgg ttcgtgtcag cagacgcgac gcaaaacaaa
    10621 cggaaccgct aaatgaacat cgatcgatca ggcacagttg ctcttatcac gggtgccggc
    10681 tccggaatgg ggttggcatc agccgaggca ttcttggaag ccggcgcgtt cgtcgtgctg
    10741 tcaggaagcc acaataaaaa ggtcagcatt caatcaacag gagtctgcaa ccatgaacag
    10801 agtactggtc atcacctacc cgaagaaaga cgatcgaatc gcgagcgtca tggccgctga
    10861 atatgccatg accaattcct ggcgcgatca gggcatcatc gaacatcttt tcgccaaaga
    10921 gaatgacggc ggcggggtgg ttgttttcaa tgagacgagc gtggagaaag tccaggcgct
    10981 cattgcgcaa cttccgctgt ttcctttctt tgagaaagtg gagtatttcc cgctcaacaa
    11041 gatctattga gcttccgcca ggttcatctt tcaacacagg agaaggttat gcaacgcgtc
    11101 agcttcaaga atcgcaacat catcatggcc ggcagcttgt gccagccacg agatttcaag
    11161 gatggcgcac gctacccggc ggtcgtcgtg gtgcatcccg caggcggcgt gaaggaacag
    11221 accgctggtg agtatgcaaa gcgcctggcc gcggaaggct ttgtcacgct cgccttcgat
    11281 acgtcctatc agggcgagag cggcggcgag ccgcgttacc tggatgagcc catgaaccgc
    11341 gtgggcgaca tctacagcgc ggtggattac ctcaccacct tgcccttcgt cgatgccgag
    11401 cgcatcggta ttctcggcat ctgcgccggt ggtggctatt ccgtcaaggc ggcctcgctg
    11461 gatcgccgca tcaaggcggt tgccaccgcc agcgcggcga atgtgggcaa cgcggcacgc
    11521 aagggatggg atggcaagag ccctatgtcc gctttgccgg gcacgctcga aatgctcgtc
    11581 aaccagcgca cggcggaagc cgccggggcc gcgatagcct acgcgcccta cgtacctaac
    11641 gtcggtgaaa gcagtccctt ccgcgatctg cgcgagggct ccgactatta cctgacgcca
    11701 cgtggtcggc atccgaacgc gcccaataag atgctcatga cctcgctcat gggctggatc
    11761 gcgttcgatg ccttcgacct ggtcgatccg ctgctgaccc aacccctcat gatctgcgcc
    11821 ggcagcgaag ccgattcgct gtggcaaagc caggaactct acgcgaaggc accaggcagc
    11881 agcaaggaac tcttcatcat cgaaagggct tcgcacatgg gtctgtatga cggatccggc
    11941 cgtgaagccg tgctcgggaa gatcacgccg ttcttccggg ccaatctctg aaggaatacc
    12001 ccctgtgagt gccagcacgc caatgacaag ttctgcaaca agcgccgggc aattgctggc
    12061 acggcagcgc aggcatgcga gtccggagct tcttgccgca gccctgcttc tccttggcac
    12121 ggtcgcggcc ctgcagagcg agtactcgct gtggtggcgc gagccggaac aggaattgct
    12181 gcctacgctt gaggaactga gcatcgggtt cgtgccgttc agcccgctcg gcaagggata
    12241 cctcaccggg aagatcgacg agacgacgac gttcgacagc accgacttcc gaaacaccgt
    12301 cccccggttc acggcggaga accgcaaggc gaaccaggcg atggtcgagc tgctcggccg
    12361 catcgccgag cggaagaagg cgacaccggc ccaggtggcg atcgcgtggc tgctctccca
    12421 gaagccgtgg atcgtcccga tccccggcac caccaaactg caccggctcg aagagaacgt
    12481 cggaggggct gccgtcgaac tgaccccgga tgacctccgc gatatcgcgg acgccgcggc
    12541 aaacattgcc gtccacgggg aacgatactc cgaggcggcg cagaagatga tcaaccgtta
    12601 aagaagcatt cacgacaatc ctgctgtgcg ggcagggtca cacgcatctc ggtcattgat
    12661 aaccgtcatc ggggtctgcg caacgcgcgc catcaaacga aaggaaccca catcatgaaa
    12721 tatcgcaagc tcggcaatac cggcaccgtc gtatccaccc tggcgctcgg cacaatgtat
    12781 tttggcgatg agacggccga gaacgatgcg ttcgccattc tcgacgcctt cctcgatgcc
    12841 ggtggaaatc tggtcgatac atccgatgtc tacgtcggta ccgtcgccga gcagatcgtc
    12901 ggccgttggc tggcggcacg tcctcgcgag ataaccgatc gcgtcatagt ggcgaccaag
    12961 ggccggttcg gtgatgattc cgatcccaat gcggtaggcc tgtcgcgccg ccatctccac
    13021 cgggcgctgg atgcctcgct gcgccgcctc gacgtggaga cgatcgacct gtatcagctg
    13081 catgcgtccg acatgcacac gccggtcgag gagacgctat cgttcctcga tgatgccgtc
    13141 cgcgcaggca agatccacta cgtgggcctg tcaaacttca ccggctggca gcttcagctc
    13201 atggtgtcca ccgccaaggc gacgggggtg cagacgctgg tcagtctgca acagcaatac
    13261 agcctgctgt cgcgcgagtg cgaatgggag atgaacccgg ccgcgcggca taacggcttg
    13321 agcctactgc cctggtcgcc gctggccgga ggtttcctga ccggcaagta tcaacgtgga
    13381 ggaaccccgg cgtccgatag ccgtgccggc tccggcaaag acctgtacca gtggatctct
    13441 gcggattatg ccggctccga tcaaaattgg gcgacgatcg aaaccgtcat ccgcatcgcg
    13501 aaagagatcg gcgccacccc ggctcaggtc gcgctgagct ggatcgccaa tcgtccgggc
    13561 gtcgccgcac cgatcttcgg cgcgcgcaac ctgcggcagc ttgacgagaa tcttgctgcg
    13621 gccaaactca cactggacga gaacgccacg aaggccctcg aagtggtcag tgcgcccaga
    13681 tcgaacggct atccttatgg cgcgttcggc gccggtcagc gcaaccgcga cttgcgggat
    13741 ggaaacccgg caccaggtct tcccgtcgcg ggcggatcag accatccgct cggccgccca
    13801 tcgctgaccg tcacttctcg cgtcagcgac tgaactcgaa ccctagggag aaccccaatg
    13861 gaccgacccc gtattttcat ccatatgcac atgtcacttg acggaaaaat cgtggggtcc
    13921 tatctgccca cggacgttgg gatggcttcc caaaggcagt actacaacct cttccttggg
    13981 cccgaccgcc atttccgcaa tcacaaggga tggctgtctg gccgcactac cagcgaggac
    14041 aacttcacgc actatcggaa gctgaagctg gatgaattcg ctccgccaat gccggaaggc
    14101 gatttcatcg ccgtcgacga cgcgccgatg cattatttct cagtggaccc gtccggcgtg
    14161 ctcgcctggg aaacgaactc aatcacctac ttcgacacca ccgcccatgt ggttcagatc
    14221 ctttccggaa aagccaccaa cgcctacaaa gacttcctgc gccgcaaagg cgtttcctac
    14281 acatcgccgg cgaggacgct ctagatctgg aagaggctgt aaagaagatc ggctccgcct
    14341 tcggtgttga cgagatcatg ctttgtggcg gaggaggcct gaactggtct ttcatccggg
    14401 cagacctgtg cgacgaggtg agcatcgtcc tgacgccggc tgcggatgga acgaagggag
    14461 cgcagaccct gttcgaggcg gatgagcgct acacccagcc actcccaacc gccttcaagc
    14521 tgaaggaagt gcaacctctg gatgatggca gcgtctggct ccgatacacg gtagaggggc
    14581 cgatcaactg agaggttctt ccggattcac cacacaatga cgaacaagaa ccggtcagat
    14641 cgaccaatca aggaaactga aatgaaacaa aagaatccac agaacaacgc gagccaaagc
    14701 aacccggctc caatcagccg ccgcggtttc ttgctgtcgg ggggcgcgct gggagccgcc
    14761 atgtgtataa cacctgcctt gggaaaaccg gcggccggac cagccccgat ctgcgatcag
    14821 aaccgcacca gctctccttt gatcactcaa cgccgcacat tgggctcagg aaagcacgca
    14881 ttgcaagtgt cggccctcgg ctttgggtgc atgggaatga actaccatcg cggcctccat
    14941 ccggaccggg atgcgatgat caagctggcc cgccaggcca cggaacgtgg cgtgaccctc
    15001 tttgatactg ccgaggtgta tgggccgttc gtcaacgaag aactcgtggg tgaggccctg
    15061 gccccgttcc gcgggcaagt cgtgatcacc accaagttcg ggtggaagat cgatccgggc
    15121 agtcgcacgt cgatcggcct ggacagtcgt ccgcaacaca tcaaggaggt cgccgaggcc
    15181 tcgctcaagc ggctgaaggt cgatgccatt gacctgttct accagcaccg ggtcgatccg
    15241 gacgtgccga ttgaggacgt ggcgggagcg gtgaaggagc tgatccaaga gggcaaggtc
    15301 aaacacttcg gcctctccga agccggggcg aagacgatcc gccgggcaca cgcggttcag
    15361 ccggtcaccg cggtccagag cgaataccat ctaatgtgga gagcacccga gaaggacgtt
    15421 ctgccggtgt gtggagagct tggaatcggg tttgtcccgt acagccccgt gaaccgcggc
    15481 tttctcggag gcaacctgaa tgaatacacc cggttcgatt ccggaagcga caaccgcaag
    15541 acactgcccc gcttcacgcc ggaagcgatg agagccaatc tggcgatcgt ggaggcgctc
    15601 aatcgattcg gccgcactcg gggagtgaca tccgcacagg tcgcgttggc ctggctgctt
    15661 gccaaacaac cctggatcgt gcccattccc ggcactacca agctggcaca cctggaagaa
    15721 aacctgagaa cggcggacct gaaattgtcg gccgccgaaa tgagtgagat cgagggttcc
    15781 gtttcgaaga ttgagatcgt gggcgaccgt tatccggcgg agcaacaaaa actggtctca
    15841 cccgattaat cccgaagctg tcacccatgg ctatgcacca cgccgcacgt ttctgaaccg
    15901 tcgggctgcg tagggagaaa atgatgaaag aaaccaacga cgaagataga acctaacaat
    15961 caagacccgt aggtcactca cgacgtgact ttattatttc cgcagcgact gctgtagcga
    16021 gtgtggagct gcaaacctgg tgaacttaca accagcacag ggagcgaacg ccatgaacaa
    16081 gcctgaattc ttcgtcaccc ccggttacgg tgagcgcaac ctaaaactgt tccactattc
    16141 ccaggcggtc aagatcggca accggctgga gctttcgggt cagggcggct ggaacgatga
    16201 ctgggagttc cccgagtcga tcacggatga gatcgctcag gcgtttcgca acgtcgagcg
    16261 gactttggct gtcgccggcg cgcgctggga gtacgtgatt catgtgaact cttaccacgt
    16321 ggggctcgac ggcgaccagg aagaaatcaa ccaggccatg acggagcggt tccgtcacta
    16381 catgcccggc cacgctccag tttggacttg cctgggagtc gctgcccttg gagatccgaa
    16441 gatgcgggtc gagatccgcg tgaccgccat ccttccagaa tgaagggaag gagccggatt
    16501 gggcattctc ggcggctcgg tagacggacc tctgccgaaa gcgggccgcc ctcgacgcga
    16561 gaagcaggac gtacacccgc cacgaatcgc ggcgggcacc atttagacga ggaggtacac
    16621 catgcgagga gcagttctct acggcccgcg cgatgtgcgc ttcgaagagc gcgacgcgcc
    16681 aaagatcatc gagccgacgg atgccattat ccgaatcgcg ctcacctgcg tgtgcgggtc
    16741 ggacttgtgg ccgtatcgcg ggctgcagcc gatcaccgaa cccacgccga tgggccacga
    16801 atactgtggc atcgtcgagg agatcggcgg cgcggtgcgg tcggtcaagc cggggcagtt
    16861 tgtcatcggc tcgttcgcta cgtccgacaa cacctgtccc cactgtcagg ccggctacca
    16921 gtcgtcatgc gtgcatcgcg agtggatgct tcgggcgcaa gcgccggtgc tccgcgtgcc
    16981 gctggcggac ggaacgctgg tgccgacgcc gggcgtgccg tcgaacgacc tgctcccgag
    17041 cctactgaca gcatcggatg ttctgggcac cggctggttc gctgccgatg cagcgaacgt
    17101 gacaccggga tcaaccgtcg tggtcgtcgg tgatggcgcg gttgggctcc tgggcgtgct
    17161 ttcggctaag cagatggggg ccgagcggat catcgcaatg agccgtcacg agaagcgaca
    17221 gcagctcgcc cgcgagtttg gggcaaccga cattgtgact gagcgcggtg acgagggcac
    17281 tacccaaatc aaagagctaa ccaacggtgt tggtgctgac tcggtgctgg agtgcgtcgg
    17341 cactcaagaa tcaatgatgc aagcgattct tgcgacccgt ccgggtggct ccgtgggtta
    17401 cgtcggcgtg cctcacggag tcctgctcga tggtgagaag ttgttctact cacatgtcca
    17461 cctccacggt ggccctgcgc cggttcgtcg ctacctgccc aagctgatcg acttggtgct
    17521 ggacaggaaa atcaatccag gcaaggtgtt cgatctgact cttccgctcg atcaggtggc
    17581 tgaaggctat cgggcgatgg acgagcgccg cgcgatcaag gcgctgctgc ggccgtagtt
    17641 cgaaacatgg acggtagaag gaacatgctt gcccgaaagg aacgctcatg aagattcttt
    17701 gcctcgaccg tcccgacccg gtgcgacgct ggaaaaacag cagcctcacc tgcacgatga
    17761 ggcgcgccac atctgggagt cgtacaaaaa gggcgtgatt cgcgacatct ccttccgcca
    17821 ggaccggctc ggcgtcgcca ccaccctcga gaggaactgt gcaggatcgc tgaagccgat
    17881 gccctgtaca tttcgcaacg atgtggagaa ggcctttgag ctgatgagaa cgaaagcaga
    17941 cggcatgttg aagccgctca tcacgtctgc gtgaaaggag gctctatagt tgtccctgct
    18001 cataatatgt tggaggcaag agattgggct agacgtgtca ggttgttttg atctatggtg
    18061 cagcaggaag aaacacttac ggaggcagta gtccagaatt gcatcgccac ggagaagtaa
    18121 ccttgtcggg gagtgatggc tcatgcatac caaaacgttc ttttgcatca tcagcgtcat
    18181 cttccttctg tcctggagat ctaacgtgga ggccaagtcg ttaccggtgg tccaggtcgg
    18241 gatcgtgcgc gacggaccct cggagcttgt tcccgagctc cgtgatctca ttcagaagga
    18301 aattctcgag atcaccagag gggaattcga ggtgcggttc cccaatgatt tgcagtttga
    18361 tggaggatgg tcggtgcaag gggtgaaaca ggcgatcgat cgtgtgctgg ctcagccccg
    18421 tgtcaatctc gtcatcgcac tcgggattct cgcttcccag gaggtcagtc aaagaaggca
    18481 actacccaag cctgtgatcg cgccgttgat cctcgatccg cacttgcagg ggctgccgtt
    18541 caagaagggc acgagcggga tgaaaaacct cagttacctc gtcaccggaa agggcttcga
    18601 gcgtgatctc gaggccttca aagaggtgtt tccctttacc cggttaaccc tcttggcaga
    18661 tcgggtgtta ctggaggcct ttccgccagt taaggaccgc gcgcgaaaga tggctgagac
    18721 gtacggcgtg aagcttaccg tggttccggt cgagacctct gccgaggcgg ccattggctc
    18781 gatccctccc gacacagagg ccgtctatct ctcgcctctc ccgcggctgc tcgccggtga
    18841 attcgatcgt ctggttttgg ctctcaaccg gcgaaaactt cccagctttt cggcagtggg
    18901 acagcgggac gtacagcgcg ggatcactct cgctctgtcg cctgaattgg atctggggcg
    18961 attcgcgcga acgatcgcgg cgaatgtgca gcgtattctg tcagggaccg acgccggacg
    19021 gcttgaagtg gcctttatcc ggggcgagca gctcgtgatc aacatggcga cagtccgtgc
    19081 gatcgacaag tggccgagct tccaagtgct gagcgaggca gagttggtga acgaggatgc
    19141 agccggcacc tcacgacgtc tgtcgctctt cgaagccgtt cgtgaatccg cagaagcgaa
    19201 cctggatctg gccgcggcga gccgcaaggt cgcggcggga gtcggccagg tgggccaggc
    19261 acgatccggt cttctgcctc aggtgctcgt cggcacgtca ggggttctga acgggcgagg
    19321 gccggatacg tttggcaccg gcgggacccc cggtcaagcc gcgattgccc ttggcggatt
    19381 ccgccagctc ctgtactcgg acgacgcctg gaccaagtac acggtgcagc agaagacgca
    19441 actgtctcga gaagaggagt ggaaccagct gcggctggat atcgcacagg acgcagccct
    19501 cgcctatctg accgtccttc ggaccaagac cgtgcgacgt attcagaagg ataacctcaa
    19561 actgacgcgt gccaatctag acatggctgc ggcccgtgag tcggtcggct atgccctccg
    19621 ggatgagctg tttcgatggg aagcagaggt ggctaacggg cagaaagccg tggtttccgc
    19681 cgaggctcaa gaacggcagg cggaagtgga cctgaaccga atcttgaatc gtcctctgga
    19741 agagaggttt caaaccgtgg agcaaaccct ggaggacccg ggattgctgg gcgatacgcg
    19801 tcagctgttc gcgtatatcg agaatccgcg gggatttcaa gtattccggg acttcgaagt
    19861 cgaagaaggg atccaggcgg ctcccgagtt gcgacggctt gacgccttga gtgcggctca
    19921 ggagcgaacc atcacgaatg ctcagcgagc ctattggctc ccagaagttg ccatacaggg
    19981 tgccgggttt cagcaatatg cccaaggggg aggaggagcg ggaagcctca cggtccccct
    20041 tggaccggtc ggctttgcgc agacccagaa caatttttat gtagcgagta tcgggttgac
    20101 gttccccctg ttccagggcg gatacaaaga tgccacggcc ctcaaggccc gtgaagaact
    20161 gcgtcaggtg cagttcgagc gggccgccgt cgcacttcag gttgaagagc gggtccggac
    20221 tacgctgtat caaaccggcg cttcctttcc cagcatcaga ctctcgcgga aagcggccga
    20281 gtcggcccgc aagaccctgg atctggtcgt ggatcaatat tcccgagggg cggtggacat
    20341 catcaagctt ctgaattcgc agaatgccgc gctgaccgcg aatcaggccg ccgccaatgc
    20401 ggtctatgaa tttctgatcg atctggcgaa ggtacagcgg gcggtggggc agatgagttt
    20461 ctttcgaagc tccgaagagc gagccgcctg gttcgaacga ctgaaaacgc attttgtgaa
    20521 tgccggcgtc tcgccggttc tgcgcgatga cccacggaac tgattgacac ggagtgactc
    20581 catgccgacc ccaaagatcg ctcgccccac tctcatacta ggagttgggc ttctgttgct
    20641 cgtggcagga gcctccgtct ggtggttcta ttttcgaatc ccaccgctcg tgggattcgg
    20701 cagcggcaac ggacggcttg aggtgcagga gatcgatgtg gccaccaaat tcccaggccg
    20761 cattgcggag gtgctggttg atgagggcga tagcgtccaa gtcggacaag tcgtcgcccg
    20821 catggatacg agttcgttga acgcacaggt gcgagaagcg gaggcgcaag tccagcgagc
    20881 caagcaaggc aagatcacgg ccaaggccgt gatcgctcaa cggcggagtg aaaccttatt
    20941 agccgaacgg gatttggaac gggctcgtgc tctctacgtc aacgccaata tctccgtgaa
    21001 agactacgat cgcgcgcggt ccacgatgga cacggcgaag tccgcgatca cccaggccga
    21061 ggcccaattg gccgaggcgg aagcggccat caaggcgagc cttgcccaat cggaacggat
    21121 tcaggcggac ctcaaggaga gcgtattgac tgcacctcgg agcggccggg tacagttccg
    21181 attggcggag cccggcgaag tgctggcagc aggaggaaag gtcctgacgc tcatcgatcc
    21241 gaccgatgtc tacatgacgg tgtttcttcc ggccgctgag gcggggaaaa tagcgctggg
    21301 tgcccaagcg cggattacgc tcgatgccgc tccgaacctc gtcatcccct ctgcggtctc
    21361 gtttgtcgcc gacaaggcgc agttcacgcc taaagaagtg gaaaccagga cggagcgcga
    21421 gaaactgatg tttcgaatca aggtcaaaat cgatcccgag ttggtcaaag ggcatgaggc
    21481 ccaggtcaaa ccaggtctcc cgggcgtggc ctacgtacaa ctcgattcgt ccgttcagtg
    21541 gcctccatcc ctgcaaacga agctgatacg atgagtgaac catccgcatc cgtagcccgt
    21601 gtcgccacgt tgacccatcg ttatggggac acgactgccc ttgatgcggt gaccttggac
    21661 attccgggcg gccgcatggt ggggttcatc ggtccggacg gagtcggtaa atccagtttg
    21721 ctggccctaa ttgccggtgc aaaaaaaatc caggccggcc aggtcgaagt gctcggcggc
    21781 gatatggcgg ctgtgcggca tcgcaacgag atctatccgc ggatcgccta tatgccccaa
    21841 ggactgggag gcaacctcta tctgacctta tcggtcttcg agaacgtgga tttcttcggc
    21901 cgcctgttcg gacagaaccg tgaggagcgc gaatggcgga tcacagacct gctgcgaagc
    21961 acggggttga cgccgtttcg ggaccgtccc gcggggaagt tatcaggcgg catgaagcag
    22021 aaactcggct tatgttgctc gctgatccac gatcccgatc tgttgattct ggatgaaccg
    22081 accaccgggg ttgatccgtt gtcgcgccgg cagttctggg acctcgttga tcggatccgg
    22141 aagcggcgcg cggggatgag cgtgctcgtg gccaccgcct acatggagga ggccgagcga
    22201 ttcgactggc tcgtggccat ggacgcgggc aaggtgcttg cgacagggag cccggcggaa
    22261 ctgaagggtc gcatgaacgt acggacgttg gaagacgcct ttgtttcatt gctccccgaa
    22321 gagaaacgtc gaggccacag cgccatcgcg atccctcctc gccggacaca cgagggcccg
    22381 ccggccatcg aagcgcatgg cctcacgatg cggttcggca gttttacggc agtcgatcat
    22441 gtgagctttc gcatcgagcg gggagaaatt ttcggttttc tcggctcgaa cggctgcggc
    22501 aagaccacga ccatgaagat gctcaccggc ctgttgcccg catcggaagg agacgccagg
    22561 ctgttcgacc ggccggtgaa cgcccaggat atggagacac gcaagcgtgt cggcttcatg
    22621 tcccaggcgt tctccctcta tggtgaactc acggtgcggc aaaacctgga gctgcatgcg
    22681 cgcctcttcc acctccagcc ggagaagatc cccgggcgtg tggctgagct gaccaaacgg
    22741 ttcaagctgg aagactatct ggatgatctg gcggaggctc tgccgctcgg aatccgccaa
    22801 cgtctctccc tggcggtcgc cgtcgtccat cagccggaga tattgatcct ggacgagccg
    22861 acgtccggtg tcgacccggt ggcccgcgac ggattttggg agctcttgat cgagctctcc
    22921 cgcaaagacc gcgtgacgat cttcatctcc acccatttca tgaacgaggg ggaacgttgc
    22981 gaccgcatct cgctgatgca cgcggggcga gtgctggtga gcgatacgcc cgaaggcttg
    23041 atccgtaccc gtggcgctgc gaacctcgaa gaggccttca tcggctacct cgaagaagca
    23101 agcggagagg cgacgcagaa agaggtcgtc gaggaagccg cagagacaat gccttccgca
    23161 tcgggaacct caagagctga tcgtggcagg gcgttcagcc ccatgcggct gttcgcctat
    23221 gcccaccgcg aagccctgga gctgagacga gaccccatcc ggctcacgtt tgcgctgctg
    23281 ggatcggtgc tgctgatgtt cattcttggg tatggcatta ccatggatgt ggaagacctg
    23341 cgcttcgccg ccctggaccg tgaccgaacg ccgcagagcc gggactacat tcagaatctc
    23401 gccggctcac gctacttcat cgagcgtccg ttcatcaccg atgatgcgga actggaccgg
    23461 cggatgcgca gcgccgagtt gagcgtggcg atcgagatcc cttcgggttt cggccgggat
    23521 ttgaagcgag ggcgccagac cgaggtcggc gtgtgggtcg acggcgccag tccgttccgg
    23581 ggcgagacca tcaaggggta cgtgcaaggc atgcactacc agtacctcgc cgacctggct
    23641 cgtcgcacct acggcgctca gccacagacc ggcctcgccg atctcgagat gcgctaccgc
    23701 tacaaccagg acttcaagag tctggaatcg atggttccgg cggtgattcc gctgttattg
    23761 gtcttcattc cggctctcat gacggccctc ggcgtggtgc gggagaaaga gctcggctcc
    23821 atcacgaatc tgtatgtgac gccggtcaca cgcctggagt ttctgctggg gaaacaactg
    23881 ccgtacattg tgctcagcat gatcagcttc ttcggtctcg tcgcgctggc cgtggtcgcg
    23941 ttcaaggttc ccctcaaggg cagctttgcc accctggcgt tgggaggagt tgtgtatgtg
    24001 atcgtcacga cgggaatcgg cttgctgatg tccgcgttca cccgtagcca gatcggcgca
    24061 gtggccggga cagcaatctt gacgatgctg cccacggtcc agttttctgg gttgaccgat
    24121 ccggtgtcct cgcttgaggg gatcggcgca ctcatcgggc aggtctggcc cgcgacgtat
    24181 ttcctcgtga tcagtcgcgg gacctttacc aagggcctag acttctggga cctctatggg
    24241 tacctgattg ccttggcggt tttcatcccg gtattgactc tgctcagctt ggcattgctg
    24301 aaaaaacagg gcacatgaag atga
//
LOCUS       DAOQPD010000057        23951 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_996_length_23951_cov_34.955725, whole genome shotgun sequence.
ACCESSION   DAOQPD010000057 DAOQPD010000000
VERSION     DAOQPD010000057.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 23951)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 23951)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23951
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_996_length_23951_cov_34.955725"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..656)
                     /locus_tag="PK063_12970"
     CDS             complement(<1..656)
                     /locus_tag="PK063_12970"
                     /inference="COORDINATES: protein motif:HMM:NF025815.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98010.1"
                     /translation="MRGASSDQHDASLHFIGGQLLLEYKDGEAVIRKCISPEAARNAF
                     SSAGIDSDWLPEHVCRYGIGPRGPWLLLRFAPGRYQIPLADPITLSGGGEPHTMLAVP
                     MPGLLFLGYGTHYYVWAYKLWKCAATKLFKAPLANVYPDGAICFGNVHPRVAHGNTIT
                     NSWRLFWDSNFSDHLANGKSNAHPDNILPFLAKLHSTEAQDYPLDDLEPAHLSIATII
                     R"
     gene            complement(1452..1889)
                     /locus_tag="PK063_12975"
     CDS             complement(1452..1889)
                     /locus_tag="PK063_12975"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98011.1"
                     /translation="MVTLQLEGQEIQLPPEIAISDDAVRKAIAPLFPQAAHATIQRTT
                     DTNGMTTIRLTKQAGTKGNYHVILRQLIESPRHVNPALTLYQAYQAESQPTQTTVESI
                     LLTQQKLRLAIEHGEKEYKETATIKERLRNTPGSPSRLLPPGF"
     gene            complement(1903..2436)
                     /locus_tag="PK063_12980"
     CDS             complement(1903..2436)
                     /locus_tag="PK063_12980"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98012.1"
                     /translation="MKTEAVPAPPPPRLEEEDDEDEQDPIASFEQDSNDFQRATISIV
                     MTLLPTDHHPDGRLTLIGVRSHNLPPQLTTARFNDLLPLPESLSQALASWEQTFTAAL
                     TARKTQRDAKAAEQQAKTVKQEKKREAERQARKPKVAKPAAAKAPPVALTPKPDREQH
                     THDSTSNTALPQAGLFE"
     gene            complement(2722..4383)
                     /locus_tag="PK063_12985"
     CDS             complement(2722..4383)
                     /locus_tag="PK063_12985"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98013.1"
                     /translation="MPAGIRTSLTRVYTYPAYLTFSSYAALPAAVREEADQMQSLWNA
                     MVDVYEVAHRQQERLHKQFLQTSRTTTRAAGGTRSIGDPFECIKQLRDQNDSLEDETL
                     LALSRTYRTAAAEYEASEHHNIDRCLPYPESMKQELSQITKRLHDTLHQLARTSPLSR
                     SHSNAVLERMKTAIRRVPVGNLPPSKETGPPTSLFFTHDFGSQGIRIQSLTRADVTQS
                     GSSFAANRLLTLHPVSQFAEDTDPRERGQRDFCRTEGELFVRNVPIPFEIILTPLLPK
                     DALLKQVSLIGSQQRPQTSVNMDSSNACLRNDTTWQWYLQFTLIVPPTQQSEPKKYGM
                     IALDFDHRLINDANPLVRVGEWVSDTGKHESVFFPARVVKNLIAAYEAREALNVQHLA
                     LKQLFVHFPFAGALADMVKEPIHSDVPLSRKRLRWIAHQAVKQAYSGPLTSIIREILS
                     QIRDTRIDVVRRRRQWRRDRAEFYDKLAHRLSREAGTIVLTPVLSAGRSGAEGSSTST
                     TRSAPLAQALAHPINMQEFIHRLQHAAPIHRTTLHFVQSMHALIA"
     gene            5271..5609
                     /locus_tag="PK063_12990"
     CDS             5271..5609
                     /locus_tag="PK063_12990"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98014.1"
                     /translation="MSIAQLPNSVFEDAPLSCVFHSAQDNLYDVGKIVGLSMHHCHVE
                     SQAEVTPGMTLSLFVVLPTKRRALVLDEALVTWVRTEEFGVRLKTIPGEDAAYLESYL
                     AGHKVDAGLC"
     gene            5657..6085
                     /locus_tag="PK063_12995"
     CDS             5657..6085
                     /locus_tag="PK063_12995"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98015.1"
                     /translation="MTVQRRTRIYVRSFSDGRYGGAEQALVAATTYRDALIRSNPPLS
                     KPVYCAILKKTNRSGISGLSCIDRWEFSKGRRVHRLYWDVQWPIENCQSRHKKFSILK
                     YGEDGAYRRALKARAAALKAISSQTFSPFASRVAANSAAA"
     gene            complement(6109..6681)
                     /locus_tag="PK063_13000"
     CDS             complement(6109..6681)
                     /locus_tag="PK063_13000"
                     /inference="COORDINATES: protein motif:HMM:NF014017.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HMZ98016.1"
                     /translation="MNPNFRNADAFTKLVLQPYRDAQFGPNTGPFLYEFQRHGLPAEE
                     FIGKLDDFFGSVSTDFRYAVEIRNAGLLGPRYHDMLRAHGVAHVYNHWSYMPPLAEQH
                     QRMKTMTAPFTVLRLLTPLKMTYEAAKKRAEPYDKIVGELPEMRKDTVSLIQEATAEN
                     RSTYVLVNNRAEGNAPLTIQALIDRLQTGG"
     gene            complement(6882..8306)
                     /locus_tag="PK063_13005"
     CDS             complement(6882..8306)
                     /locus_tag="PK063_13005"
                     /inference="COORDINATES: protein motif:HMM:NF012798.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HMZ98017.1"
                     /translation="MKAGRWVAHTQPRLDHPDQWTREVAAEWVAAVLSMKKGDFCQTT
                     YLRQGQQGIPISPRHKMQLLSALNVFFRDCQEWEWIPRRFDPRRAFAVPRMLLALIHP
                     NPKPLPDDLWAKALSAGLQLGADDLASLSPRWPTRRFYPIEMVRAVAMVWLFSGLRSD
                     EIVRLRVGCATTKVLDEQRGKTVCLLEVPTNKTSRSFVKPVDPIVAAVIDAWEQVRPQ
                     QARFIDRKTGEPVPLLFAFRGRPLAPPYLNHTVIPLICTKAGIPRHDRHGTITSHRAR
                     STMATQLLNSPDHPMTVFELQQWLGHRSVSSTLHYLAITPTRLSESFLKSNHTHRNLR
                     TVQVLIDQDVVLSGDAGTQPWKFYDLGHGYCRYDFFEHCPHRMACAKCSFYLPKGSTE
                     AQLLEGKINLLKMRQEIPLQPAELAAVDEGIEAFERLLTQLRQTPTPAGLTPLQIDDA
                     KTSARESGVQAGLPETSAARPTVT"
     gene            9331..11022
                     /locus_tag="PK063_13010"
     CDS             9331..11022
                     /locus_tag="PK063_13010"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF014425.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 39 protein"
                     /protein_id="HMZ98018.1"
                     /translation="MKREGEDGMEWWNPVARRCLEMTLLALVGGWAYFVNLHLSLLEG
                     SEGLYAGIAGEMGRRREFFDLTYHDVPYFNKPPLFFWLLNLSTSIWGDHEIALRLPGS
                     LAAVGTIILTYVLGVRLVSPAAGFWAALVVATSHVFLWYGRRVLFDSTLTFLVTLALF
                     AWIQVQLLGRSSRWYLLAFVSMALGAMLKEMHGFFLPLLVMALYAAIQRDTRMLKDGY
                     FWAGFALAVALMAGYAQMLGPGYQHHFRISNAIQSVWNTAFTRTSGPATDGHPLYWYL
                     GMMWADFFPWCAVLPSALLLLWAQRPFRAHPTELLLLVWVLSLFTAFSLATLKREPYL
                     TTIVPGIGLMIGYYYHRLFSSAEDSAAMTPLLRVLLGVLAVTFAAGMFFGAAPLRRRW
                     LVSTAVVSPMFIVTIVSLAGLLLYAVLRSRVRLALGMVGALAVAYVVLVVNYVFPAID
                     QAASPRKAVEEIKTLALGTQPALFMYIPGWPKNEDALYYLKRDNVVPDLPSQDAVREA
                     VRTHGAIRVVTEEQHAAALQSQAGLVVGKLQEFRQPGRKHLFLLSVQEQTSARVL"
     gene            11338..11763
                     /locus_tag="PK063_13015"
     CDS             11338..11763
                     /locus_tag="PK063_13015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98019.1"
                     /translation="MHPIHPMVVHFPIALLLASTLFDALAFRWRRHQFRDTSLSLLVL
                     GILAAGAAVLTGHFAEEAVERSGIPKQAIEIHEELGGSVFWVFLGLLGLRLASCWGWM
                     REQPMLVLVIGLSGGLLLLIASYFGGDLVYRFGAGVLPR"
     gene            11814..12170
                     /locus_tag="PK063_13020"
     CDS             11814..12170
                     /locus_tag="PK063_13020"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98020.1"
                     /translation="MTTRIVMLLILCMLPATAQADASLSRAPWKERAVLRTGQVVQGD
                     YFAFGPHVEISGIVNGDVIVAGAKVILSGTVAQDARVAGAQVVSISLTHRHVVSRERC
                     SSASDMPVIQNHQQDS"
     gene            12399..12638
                     /locus_tag="PK063_13025"
     CDS             12399..12638
                     /locus_tag="PK063_13025"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98021.1"
                     /translation="MMSHHETDDRVLEVIVRSQGRTLDDIVLECPELTWNQVFIVIDR
                     LSREGAIRLMPKERGCYTVHLASNVFHDARQYARV"
     gene            12852..13100
                     /locus_tag="PK063_13030"
     CDS             12852..13100
                     /locus_tag="PK063_13030"
                     /inference="COORDINATES: protein motif:HMM:NF022603.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2934 domain-containing protein"
                     /protein_id="HMZ98022.1"
                     /translation="MKAQTTQPFREKKPHTMQVEQPNVPVSTRKAAGSAQAAVDDLHA
                     RITARAYELYVVRGCRNGYHLEDWLDAERVILDRAVTK"
     gene            13753..14355
                     /locus_tag="PK063_13035"
     CDS             13753..14355
                     /locus_tag="PK063_13035"
                     /inference="COORDINATES: protein motif:HMM:TIGR02175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HMZ98023.1"
                     /translation="MWQIRIHGRGGQGVVTAAELLAMAAFMDGKYAQAFPSFGSERMG
                     APVVAFCRVAEGAIRTRETVTRPDVVIIQDPTLLHQVDLFGGLAPLGFVLINSTQTLD
                     ALHIEEFLSTLPLGHVCAFSATDLGLKYLKRPIANGPLLGAFAAITGLIRLASVESAI
                     QQKFPGAVGEANRAAAREAFDVVTTSITEQRGIVHHAHAD"
     gene            14339..15592
                     /locus_tag="PK063_13040"
     CDS             14339..15592
                     /locus_tag="PK063_13040"
                     /inference="COORDINATES: protein motif:HMM:NF013974.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase C-terminal domain-containing
                     protein"
                     /protein_id="HMZ98024.1"
                     /translation="MRMQIEGSQAVAEAIALCQPEVIAAYPISPQTHIVERLSRKTKQ
                     GHIGRCQFLNVESEFAALSVLIGASASGARTYTATSSQGLLFMAEAVYNVAGLGLPIV
                     MTIANRAIGAPINIWNDHSDSMALRDAGWIQLFAEDNQDAVDLHIQAFRLAESLSCPV
                     MVCMDGYVLTHAYEPVDVPDAVQVNAYLPPYDPVQVLDPERPVSIGAMVGPEAFTEVK
                     YFSHQQHLRALEVMPELVEVFEQHFQRRSGGLCSAYRMEDADIAVIAMGSVIGTIKDA
                     VDELRNTGVRVGCVKIGCYRPFPKFQVSALLEKTTRVIVVEKDLAVGMGGIVSADVQS
                     ALQGRQISVHTVIAGLGGRSISTSSLKHMILEARAERLTEPYFLDLNKTVIEQELARR
                     RDIRRAGPVAEHMLQTMNVIGTKVS"
     gene            15604..16593
                     /locus_tag="PK063_13045"
     CDS             15604..16593
                     /locus_tag="PK063_13045"
                     /inference="COORDINATES: protein motif:HMM:NF014794.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HMZ98025.1"
                     /translation="MTTERIKFYQTGTFTAGNRLLDEATRTVQSRLDRTNSLNSGHRA
                     CQGCGEALGARYALDAAMRASHNQLIAVNATGCLEVFSSPYPESAWQIPWMHSLFGNA
                     PAVASGIAAALRAKRRDDVTVIAQGGDGATVDIGFGCLSGMFERNDDVLYLCYDNEAY
                     MNTGIQRSGATPPFARTNTTQAVGEHPGNPIGNGKNVPRIALAHGIPYVATASVADLH
                     DLERKVTKAIGVRGARYIHVHVPCPLGWGSDPAHTMKVARLAVESGLFPLFEAEFGKV
                     ICSTPIRRKVPVERYLELQTRFKHLFGPPQDTEALAAIQAMADDNIAVYGLME"
     gene            16602..18230
                     /locus_tag="PK063_13050"
     CDS             16602..18230
                     /locus_tag="PK063_13050"
                     /inference="COORDINATES: protein motif:HMM:NF009410.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding protein"
                     /protein_id="HMZ98026.1"
                     /translation="MERTPFAITLDPNTSLANHTGNWRTMKPIYVDRLPPCNHACPAG
                     ENIQAWLYHAEEGAYEEAWQQLMQDNPMPAIHGRVCYHPCESACNRGHIDEAVSIHAV
                     ERFLGDQAIAQGWRVACAPRTGKNVLVIGAGPSGLSTAYHLARMGHQVTIHEAGPQAG
                     GMMRYGIPKYRLPREIVDAEVARIQSMGVTIRLNSRVDDLEATMAEGRFDAAFLALGA
                     HLARRVEIPGVDAKRVLDAVTFLRDMEGAARPKLGRRVAIYGGGNTAIDVARSVERLG
                     MEPVIIIYRRDLGHAPAFASEITEAQDEGVQFQWLRRIAQGDESTLTVEEMALDEQGK
                     PQPTGRFERIEADSVILALGQRADTGFLRRVSGLRVREDGTIEVDGTMMTGRPGIFAG
                     GDMVPGEQSVTVATGQGKKAARHIDAYLRGSAYVKPEAHEPATFSRLNTWYYTDADAS
                     KQPLLNLVRRRSSFDEIVGGLDADTALLEARRCLSCGNCFNCDNCYAVCPDSAVIKLG
                     PGKRYAINYDYCKGCGLCAEECPCGAIDMVREVK"
     gene            18316..18798
                     /locus_tag="PK063_13055"
     CDS             18316..18798
                     /locus_tag="PK063_13055"
                     /inference="COORDINATES: protein motif:HMM:NF012790.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HMZ98027.1"
                     /translation="MALAQRACSGTALVLCAVLVGPVHAAKVSDAAATHEWMSTPVRT
                     AAEQMLAAMPDDYYSIKGVAAEKAIATGVPHVLDVREPNEFAVEHIPGAKNVPLRSLM
                     TAIDDLPGDKAASLIVYCKTGHRGAIALAVLRMLGYANVLSLYGGLDGWKAAGFAIEK
                     "
     gene            18832..21273
                     /gene="ppsA"
                     /locus_tag="PK063_13060"
     CDS             18832..21273
                     /gene="ppsA"
                     /locus_tag="PK063_13060"
                     /EC_number="2.7.9.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014450078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008986 - pyruvate, water dikinase
                     activity [Evidence IEA];
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate synthase"
                     /protein_id="HMZ98028.1"
                     /translation="MSYTATTTQAAIRWFEDIGIDDIPLVGGKNASLGEMYRELASRG
                     VKVPNGFAITAEAYRSFLRTTGLDQRITQIIRGLDTRDLDNLRQRGRQIRQAMLAASL
                     QQDLERAIVEAYDRLSDGHVDLVDVAVRSSATAEDLPDASFAGQQETYLNVQGHQALL
                     DACKRCFASLFTDRAISYRVDKGFDHFKIALSIGVQRMVRSDLSASGIMFSIDTETGF
                     RDAVLINASYGLGENVVQGAVNPDEYYVFKPTLRQGFRPILQKMLGSKEFKLVYDVGG
                     SKLVKNVPVPPDDRARFAITDDEILTLSRWACMIEDHYSAKKGRTSPMDMEWAKDGHT
                     GELFIVQARPETVQSQKRQDSLELYRLGRKGKVLLTGRSVGSKISLGPVRVVKHLQQL
                     RDFTSGDVLVTDKTDPDWEPVMKKASGIITNRGGRTCHAAIVSRELGVPAIVGTGNAT
                     EVLRDCQMVTLSCAEGDTGFVYEEALPFTVQRVELSDLTRPRTKIMMNVGNPEEAFAL
                     SFIPNDGVGLAREEFIISTYIKVHPLALLNYDRLDDAAVKAEIDRLTVGYADKAQFFV
                     DKLAQGVAMIAAAFYPKDVIVRLSDFKSNEYASLVGGRGYEPTEENPMIGFRGASRYY
                     DSRYQAGFALECRAMKKVRGEMGLTNVKLMIPFCRTVEEGRLVQAEMAKHGLTRGENG
                     LEIYVMCEVPSNVVLADQFAEVFDGFSIGSNDLTQLTLGVDRDSEIIAHLFDERNQAV
                     TSMMASVITTARKKGKKIGICGQAPSDYPEVASFLVEQGIDSISLNPDAVLKTTMAIL
                     KLEQGLQRGPAQRTG"
     gene            21296..22498
                     /locus_tag="PK063_13065"
     CDS             21296..22498
                     /locus_tag="PK063_13065"
                     /EC_number="2.7.2.3"
                     /inference="COORDINATES: protein motif:HMM:NF012389.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HMZ98029.1"
                     /translation="MKRIISDLPHDRYRERTVLVRVDFNVPLDHGRIREDYRLRQAIP
                     TIEYLSQRGAKVILASHLGKPKGKVVPALSLKPVADRLGQILRVPTVKFVEAAVGESV
                     KQTLTTLKPGEVLLLENLRFEPGEEANDPVFAKQLAALAELYVNDAFGTMHRAHASTY
                     GAAQLFTDRLAGFLVRKEMDVLSQVRDRPVRPFRVVVGGIKIKDKLSALKALLPKADT
                     ILLGGGIAYTFLAAQGVATGDSPVEPEFIPWAKDVLAQYRKHILLPEDHVIAANAEQR
                     DRLQLVHREIPAGFMGLDIGRDTSLTFAHELLQGTGTIFWNGPLGAFEVDECADGTVD
                     IARAMALAHWRGAFTVVGGGDTVAAVRKAEVLETEISHVSTGGGASLKFIGGEELPGI
                     AVLSEQSQ"
     gene            22517..23575
                     /locus_tag="PK063_13070"
     CDS             22517..23575
                     /locus_tag="PK063_13070"
                     /EC_number="1.2.1.59"
                     /inference="COORDINATES: protein motif:HMM:NF003251.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HMZ98030.1"
                     /translation="MRKVKVAVNGYGVIGKRVADAVKQQEDMELVGVADVVTDYRIKT
                     AAVLGLDIYAALPDKAQAMRAADIPVAGTLDDLLRKVDVVADCTPKKIGAANKILYEQ
                     AGVRAIYQGGESHALTGHSFVAQANYETAIGRSSTRVVSCNTTSIVRTLGALKKAGLL
                     KRARGTLIRRASDPWEAHLDGIMNTVIPEKTIPSHQGPDAKTVDPDLDVVTIAAKASH
                     NSSHLHTWWVELTRSASKEELLAAFRLAPRIAFIRMHEGVAALNSTIELMSDLGRRRG
                     DLWEVALWEDVLTVNGNEAYYTYQVFNQAIVVPETIDAIRALTGLESQAERSIQKTDQ
                     ALGIAKEFLRSSEHVLMA"
     gene            23710..>23951
                     /locus_tag="PK063_13075"
     CDS             23710..>23951
                     /locus_tag="PK063_13075"
                     /inference="COORDINATES: protein motif:HMM:NF019845.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HMZ98031.1"
                     /translation="MAQTMKAFVMKKLGSVGMMEKPIPDLGPNDAIVKTTAALICTSD
                     VHTVGGAIGERTNLTLGHEAVGVIYKLGSAVKGFREG"
BASE COUNT         4912 a         6278 c         7471 g         5290 t
ORIGIN      
        1 cgaatgatgg tggcaattga gaggtgagcc ggctcaagat catcgagagg atagtcttgt
       61 gcctcagttg agtgaagttt cgccaggaaa ggtaggatat tgtccgggtg ggcgttggat
      121 ttcccattcg cgagatggtc ggaaaagtta ctatcccaga atagtcgcca gctgtttgta
      181 atcgtgtttc cgtgggcgac ccgtggatgg acgtttccga aacagatcgc cccatcaggg
      241 tacacgttag cgagcggtgc tttgaagagc ttcgttgccg cgcacttcca tagcttgtag
      301 gcccagacgt aatagtgggt cccgtacccg agaaacagca accctggcat cgggacggca
      361 agcattgtgt gtggttctcc gcctccggaa agtgtaatgg ggtcagccaa tgggatttgg
      421 tatcgaccag gggcaaagcg gagtagtagc cacgggcctc tggggcctat gccatagcgg
      481 cagacatgtt ctgggagcca gtcggaatct atcccggctg aagagaacgc attcctggca
      541 gcctctggtg aaatacattt tcggataacc gcttcaccat ctttgtattc aaggagcaat
      601 tgcccgccga tgaagtgcag tgacgcgtcg tgctgatccg agctcgcacc tctcatgttt
      661 gcgcctcatg tggtgcagtg caaagatctg accagcacct gaaaatcgtt tcccatgctg
      721 acggattgtc gagtaaggct ttagtcgtgc tatgcatgga ttgttgcatg atttgcgccc
      781 gtttccattg gcgagccaaa gctttgagat cccgtttatt ccattggtac gggtgatctg
      841 gggactcgta gtcgtagctg atgtcgagga acagagatcc ggtgcagtgg ccgaggatgt
      901 cgatgacctg gggaaatcct gaaatgggaa agctgcgtcg cgcacagcgt cttctgaagt
      961 caagaaattg gacgttgcat cggtgttgag gattcaaaaa gcatcgtgga attgtagtgt
     1021 gctcgctgag ttcttcctga atgttcgtcc aggtgggagc gtaggaatag tgtcccaccc
     1081 aggccgctgc gatacagatt ggaagcggtg cctcctcgaa ttcggattca caatcataat
     1141 tttccagatg tatgggaatg aatgggaagc ggtctcgaat ccattcggtg tcccagctat
     1201 cgagcgggaa gtagtgttgc tcgattagct taatgaactc ttcttgaagt tgttctgcgg
     1261 cctccttgat gcttccatgc ggaagggtgg cggcggtcgt gcgaaacctc cggggaaaga
     1321 tctcgtggaa cgcgttgacg atagaaaagt ctcgctctcg ttcctccagg tattcgaggc
     1381 atgaggggac cgagataacc tctatgtttt tgagggatgc gagaacgagg cttaatggcg
     1441 cggagggcgg gttagaaccc aggtggaagg aggcggctgg gcgagccagg agtgttcctg
     1501 agtcgctcct taatggtagc agtctctttg tattcctttt caccgtgctc aatggcgaga
     1561 cgcagctttt gctgcgtgag gagtatggat tcgaccgtcg tctgggttgg ctgggactcg
     1621 gcttggtatg cctggtagag cgtgagggcg ggattgacgt ggcgggggga ctcgataagc
     1681 tgacggagga tgacatggta atttcctttc gttccagcct gtttcgtgag cctaatcgtt
     1741 gtcatcccat tcgtgtcagt ggttcgctga atggtggcat gggcggcttg cgggaagagg
     1801 ggggcaatcg ctttgcgaac cgcatcgtcg ctgatggcga tttcgggggg caattgaatt
     1861 tcttgtcctt caagttgaag cgtaaccata aggctccttt cgctactcga ataagccggc
     1921 ttgagggagg gctgtgtttg aggtggaatc gtgtgtgtgt tgttcacgat ccggtttggg
     1981 tgttagggcc acgggcggcg ccttcgcggc ggccggctta gcaactttgg gttttctggc
     2041 ttgccgttcc gcttcgcgtt tcttctcctg tttcactgtc ttggcctgtt gctccgcggc
     2101 ttttgcgtcc cgctgggttt tccgtgccgt taacgctgca gtaaaggtct gctcccaact
     2161 tgcgagggcc tggctcagag attccggaag gggcagtaag tcgttgaatc gtgcggtagt
     2221 cagctgcggc gggaggttgt gactccgtac gccgatgagt gtgaggcggc cgtcagggtg
     2281 gtggtccgtt gggagcagcg tcatcacgat ggagatcgta gctcgctgaa aatcgttgga
     2341 gtcctgttcg aagctggcaa ttggatcctg ttcgtcttcg tcgtcttctt cttccagccg
     2401 tgggggcgga ggagcgggca ccgcctcggt cttcatagga actggctcgg ttgctagctg
     2461 gggcatgact gaggaaacgt ccccactctg aggcgggtca gcagaggaag aattggcagg
     2521 tatgttgttc gtaaccactt gggcgtgtgg gagcaaatcg acagtgccaa gcatggaggt
     2581 cctcattatg gtgtgcacaa tgcagggggg atcgtgaggc ggtggttatt gtcgtggtag
     2641 gcgctggctc aaggactgga gtgtgttggg gcgaagctct tggttgagga tgtcggagtc
     2701 tatttgcaag agctgcgtaa gtcaggcgat cagggcatgc atggattgta caaaatggag
     2761 tgtggtccga tggatgggcg cggcatgctg tagacggtga ataaactctt gcatgttgat
     2821 gggatgtgcg agggcttgtg ctaacggcgc gcttcttgtc gtactggtag aagagccctc
     2881 ggcacctgaa cgccctgcgc tcaatactgg agtcagcaca atagtcccgg cttctctcga
     2941 aaggcgatgc gcaagtttgt cgtaaaactc ggctcggtct cggcgccatt gccggcgccg
     3001 tctcactaca tcgattcgtg tgtctcggat ttgcgagagt atttctcgga ttatgcttgt
     3061 gaggggaccg ctgtaggcct gtttaactgc ctgatgagca atccatcgaa gcctctttct
     3121 gctcagtggc acgtcgctgt gaatgggctc cttgaccata tcggcgagtg ccccagcaaa
     3181 tggaaaatga acaaatagtt gtttgagggc gaggtgctga acattaagcg cttccctggc
     3241 ttcgtatgcc gcgataagat tctttaccac ccgtgcggga aagaagacgg attcgtgttt
     3301 gcccgtgtca gatacccatt ctcctaccct aacaagcggg ttagcgtcat ttatgagtcg
     3361 atgatcaaaa tcaagggcga tcatcccgta ttttttgggt tccgattgct gggtcggcgg
     3421 tacgattagc gtgaattgaa ggtaccactg ccatgtcgtg tcgttcctga gacatgcgtt
     3481 ggaactgtcc atgttgacgc tcgtctgtgg tcgctgttgt gagccaatga gagaaacctg
     3541 tttgagaaga gcgtcttttg gcagaagcgg agtaaggatg atttcaaacg gaattgggac
     3601 gttgcgaacg aaaagctccc cctcagttct gcaaaaatct cgttgccccc gttctcgggg
     3661 atcggtgtcc tctgcgaatt gcgacaccgg gtggagtgta agcaggcgat tggcggcaaa
     3721 tgaggagccc gactgggtca cgtctgcgcg agtcaacgat tggattcgaa ttccttgcga
     3781 accgaagtcg tgggtaaaga ataacgaggt aggtggacct gtttccttgc tgggtgggag
     3841 atttccgacg ggcacgcggc ggatggcggt tttcattcgc tcgagcacgg cattgctgtg
     3901 tgaacgagac agagggcttg tgcgtgcgag ttgatgcagt gtgtcatgca gacgtttggt
     3961 gatctgggaa agctcctgct tcatgctctc agggtaaggg agacatcggt cgatattgtg
     4021 gtgttcggag gcttcgtact cagccgcagc tgtgcgatag gttcgagaaa gggcaagaag
     4081 agtctcgtcc tcgagggagt cgttttggtc acgcaattgt ttgatgcact caaagggatc
     4141 gccaattgaa cgtgtgccgc cagctgcgcg cgtcgttgta cgactcgttt gaaggaattg
     4201 tttgtgaagg cgctcctgtt ggcgatgggc gacttcataa acgtcgacca tcgcattcca
     4261 cagcgattgc atttgatcag cttcttctct gaccgcagcc ggcaaggcag cataggaaga
     4321 aaatgtgaga tatgcgggat acgtatagac ccgtgttagc gatgtcctaa tgccggcggg
     4381 catggtgcaa tctcctcttc aagactctcg ggtgtcagtg cgacgcattg ctgtgcttcg
     4441 cgcatgatcg gtttcaagtg actgtaggcg acagtgccca aggagatttt aagtggtttc
     4501 cccatctgag cgtaggagca tttgccttat gtgattgggg ttccccctaa cggaacggca
     4561 atggccgtat cggagtaggt gatctttgga agggcgaagt agactcccgg ggtgcgcttt
     4621 tcaaagagat aggatggaag tccgattgtg catcgtgggg tttgtgtcgg ctttttagct
     4681 ggttgtgttg gtgtatggaa tgtccttcac tcctcgacgt gtctatggcc agggtctttg
     4741 cagcattgaa gtgttgatca agagatgcct gaatccatga ggttgcgatt ggtgatatag
     4801 agcattccct tttgcgcccg attattctta catcaactca cgcaggtaat actcaaaagg
     4861 tggtttcaat agaacatgtc ataaggcgat cccatgcgat gggctgacca atacaacgtt
     4921 atgcggtcga tgttattgtc ttcccccgca actcattggt gggttcgtga tctgactctc
     4981 cgcctagacg ccaaagaccc ggttgatgtg ttgaatggac tcgaggttgt ggcaagactg
     5041 atgcggatgc gtcatgaggc cgttcgcgca ggagaatggg atcagttgga gtgtcagaaa
     5101 ccgaccgggg aagacgggat atcaatgaaa gactgagaca aaaactccta gtcgtgaaga
     5161 tatgatctca ggtgaccagg gcttttagat cgtgatacac gggcgagtgg ttcttggtcc
     5221 cgtcgaaaga ggaatatgac aaagtcgata gcgtgagtac actttgatct atgtccattg
     5281 cccaactgcc aaatagcgtt ttcgaggacg cgcctctgtc ctgtgtgttc cattcagcac
     5341 aagacaatct ctacgacgtg ggcaagattg ttgggctctc aatgcaccac tgccatgtcg
     5401 agagtcaggc cgaagtgacg ccggggatga cgctgtcctt attcgttgtc ctgccgacaa
     5461 agcgtcgggc tctcgtgttg gatgaggctt tggtgacgtg ggtacggacg gaagaattcg
     5521 gagtacgttt gaaaacgatt ccaggtgaag atgccgctta cttggagtcc tacctcgccg
     5581 ggcataaggt ggacgctggc ttgtgttgaa tattcatcgc attgatcacg aggcctccca
     5641 cacgcactgt tggcgggtga ctgtacaacg tcgtacccgc atttacgtgc gaagcttcag
     5701 tgacggccgc tacggcggag ctgagcaggc gttggttgca gccacgacct accgggacgc
     5761 actgatcagg tccaatcctc cgctgagcaa gccagtctac tgtgccattc tcaagaagac
     5821 gaatcgctct ggcatttcag ggctgagctg tatcgaccga tgggaattct ccaaggggcg
     5881 ccgcgtccat cggctctact gggacgtcca atggccgatc gagaactgtc aatcccggca
     5941 caagaagttc tccatcctga agtatggaga agatggggcg tatcgacggg ccctcaaggc
     6001 cagggcggcc gccctcaagg cgatctcgtc acagacgttt tccccattcg cgtcgagagt
     6061 cgctgcaaac agtgcagctg cataggagtt gtgggtccag attgcgtttc agcctccggt
     6121 ttgtaggcgg tcgataagtg cctgaatcgt cagtggggca ttcccttcgg ctcggttgtt
     6181 gacgaggaca taggtcgacc gattctctgc tgtagcctcc tgtataagac tcactgtatc
     6241 tttgcgcatc tctggtagct cccccacgat tttgtcatag ggttccgctc gtttcttcgc
     6301 tgcctcgtat gtcattttta atggggtcaa gagacgaagg acggtgaacg gggccgtcat
     6361 ggtcttcatg cgttgatgct gttcggccag cgggggcata taagaccaat gattgtagac
     6421 atgagcgact ccgtgcgccc tcagcatgtc gtggtagcgg ggcccgagca ggccagcatt
     6481 ccgtatctcc acggcgtagc ggaagtccgt tgagacgctg ccgaagaagt catcgagttt
     6541 cccgatgaat tcttccgccg gcagcccgtg ccgttggaac tcgtagagaa aagggccggt
     6601 gtttggaccg aactgcgcgt ctcgataggg ctgcagcacg agtttggtga aggcgtcggc
     6661 attgcgaaag ttggggttca ccggcccagc gcgcgagctt tagcgagcat gtttcgcata
     6721 agtgggaatt atgtggaatt agtgttcaac cgagcagttg gctcgcatgc catgtcatgc
     6781 aaaccccacc gaacgagtgc tgctcaggaa gaagggggca cctggcctca cccgataggg
     6841 ccatctttgg gattacgctg gtgctgagct gatgacagtg attaggtgac cgtcggtcgt
     6901 gcagcagatg tttcgggtag cccagcctgc acgccacttt ccctcgccga ggttttcgcg
     6961 tcatcgattt gaagaggggt cagaccagcg ggagtgggtg tctgccttag ctgagtgagg
     7021 agccgttcga acgcctcgat cccttcatcc acggccgcaa gttccgccgg ttgcagcggg
     7081 atctcttggc gcattttcag taaattgatt ttcccctcaa gcagctgcgc ctccgttgaa
     7141 cctttgggaa gatagaacga acatttggca caggccatcc ggtggggaca atgttcaaaa
     7201 aagtcgtacc ggcaatatcc atgaccgaga tcgtagaatt tccatggctg ggtgcccgcg
     7261 tccccgctca agaccacgtc ttggtcgatc agcacttgta ccgttcgtag attccgatgt
     7321 gtatgattcg atttcaggaa tgactcagac aagcgtgtcg gcgtgatagc cagatagtgc
     7381 aaggtcgaac tcacactccg gtggccgagc cattgctgaa gttcaaacac cgtcatcggg
     7441 tggtcaggac tattcaggag ttgcgtggcc atggtggagc gggcgcggtg actcgtgatc
     7501 gtcccatgtc gatcatggcg agggatcccg gccttcgtgc agatgagtgg aatgaccgtg
     7561 tgatttaggt agggtggggc caatggtctt cctcgaaagg caaacaagag cggcactggt
     7621 tctcccgtct tgcggtcgat gaaccgcgcc tgctgtgggc gaacctgttc ccaggcgtcg
     7681 atgacggcag ccacgatggg atcgactggt ttcacgaagg accgggaggt cttattcgtc
     7741 ggcacctcga gcagacacac ggttttcccc cgctgctcgt ccaacacttt cgtggtggcg
     7801 cacccgactc ggaggcgtac gatctcatcg ctgcgcagcc cggaaaataa ccagaccatc
     7861 gcgaccgcgc ggaccatctc aatcgggtag aatctgcgtg tgggccaccg tggcgagagg
     7921 gaggctagat catcggctcc cagctgtaat cccgctgaca gcgccttcgc ccacagatcg
     7981 tcggggagag gttttggatt cgggtgaatg agagccagca gcatgcgcgg aacggcaaac
     8041 gcccgtcggg gatcaaatcg acgggggatc cattcccact cctggcagtc gcggaagaag
     8101 acgttcaagg cgctcaggag ttgcatttta tgtcgcggtg aaatggggat gccttgctgt
     8161 ccttgccgca ggtaggtggt ctggcagaag tcccccttct tcatgctgag caccgcggcc
     8221 acccattccg ccgccacctc ccgcgtccac tggtcgggat gatcgaggcg tggttgcgtg
     8281 tgcgctaccc agcggcctgc tttcatgagg acggctctcc cgtttcgtcg gctcagaaat
     8341 tggcgggtgg aggtgtggaa ccgtcggttc accgcgcacg cccatctcgg aggcacgcct
     8401 gtttccccta cctgggcttc taggagcctg tccgacattg ccgaaattga ctgatatggg
     8461 aggatgaaat catattgatc gaattgaaat cgttgatcct gagccgaatg tgtgcacacg
     8521 aaactttcgt gtttcctaat gtcggacagg ctcccagcag gctgcggaaa aactcgattg
     8581 ttgcgtcaga cgccgcgatt agctcacgtg ccgtgtcggt gtcagaatcg tccgcaggat
     8641 gcgcaaaaag gccgtccagc aaggccgcag cgtcacgtct gtggacgggc gcgagtcggt
     8701 gagcgcccgg tgtcccggag gcgaatcgtt cattcgtacc cgcccacccc gagcctgcca
     8761 agacaagccc ttttcccgtg gccgtacgtt gagcgtttga ggttcacgac gcgctgaata
     8821 aagcgcacca cgcttgtgaa cgccgtcgag atagtgaggc ggcagtgtct tgcgagaatg
     8881 ccgctggcgg actttttccg catcctgcta ggaaagtcag gtgccggact ggaggcgggt
     8941 gatcgacgag cttcccgagc ctgggaaagc ttttcgaaac gggaccagaa ccggttcgtc
     9001 ggtcgcttgg ctgccaagtg agggctcgat caattgtggt cttgttgcgt gaagccgtat
     9061 gatagagcgc aggggcatgc gggtgtaagg ggctgatggt aaaagggttg gtcggggacc
     9121 atgagcatag ttgcgtcgga acgccaaaac cccatttgca agctgtccaa catgatcgat
     9181 ctcgttgccc gccatgtttg aaccattaat tggccgttga tagtgcgtgt gtttgggggc
     9241 tccatcacac acttcgtgga tgtcgatgcg aaatctgccg atatgttgaa tatgctgcga
     9301 agcgtcgaat gagtgttcat aggaggagga atgaaacggg aaggggaaga tgggatggag
     9361 tggtggaatc cggtggcgcg tcgatgtctt gagatgacgc tgcttgcgtt ggtcggcggt
     9421 tgggcctatt ttgtcaatct ccatctgtcg ttattggagg ggagcgaagg actgtatgcc
     9481 ggcattgcgg gagaaatggg gcgccggcgt gaatttttcg acctgaccta tcacgatgta
     9541 ccgtacttca ataagccgcc gctgtttttt tggctgctca atctctcgac atcgatatgg
     9601 ggcgaccacg aaattgcctt gcgcctgccc ggctcgctgg ccgccgtggg caccatcatc
     9661 ctgacctatg tgcttggagt caggctggtg tctccggcgg ccggattctg ggcggcgctg
     9721 gtggtcgcca ccagccatgt gttcctctgg tacgggcgcc gtgtgctgtt cgattcgacc
     9781 ctcacatttc tggttaccct cgccctcttc gcgtggattc aggtgcaact gctggggcga
     9841 agctcacgct ggtatctgct ggccttcgtg agcatggccc tcggtgcgat gttgaaagag
     9901 atgcacgggt tttttctccc gttgctcgtg atggcgttgt atgccgccat tcagcgcgat
     9961 acgcgtatgc tgaaagatgg atacttctgg gccgggttcg cgctggctgt cgcgctgatg
    10021 gcgggatacg cgcagatgct gggtcccggg taccagcacc atttcagaat cagtaatgcg
    10081 atccagtcgg tctggaatac tgcgttcacc cgcacgtccg gcccggctac cgacgggcat
    10141 cccctgtatt ggtatctggg gatgatgtgg gccgactttt tcccctggtg cgcggtgctt
    10201 ccgtcggcgc tcctgttgct ctgggcccag cgcccgtttc gtgctcatcc cacggagttg
    10261 ctcctattgg tctgggtgtt gagcctcttt acggccttca gtctggcgac cctcaaacgg
    10321 gagccctacc tcacgacgat cgtgcccggc atcggcttga tgatcgggta ctactatcac
    10381 cggctgttct cgtcggccga ggactctgct gcgatgacgc ccctgctccg tgtgttgctg
    10441 ggtgtgttgg ccgtgacgtt cgccgccggg atgttcttcg gcgcagcacc gcttcgccgc
    10501 cggtggctgg tgtctactgc cgtggtgtcg ccgatgttca tcgtgacgat cgtttcactg
    10561 gccggcttgc tcctctatgc cgtgcttcga tcacgcgtac gcctcgcact cggcatggtc
    10621 ggggctcttg cggtcgctta cgtggtgctg gtggtaaact acgtgtttcc cgcgatcgat
    10681 caggccgcgt cgccccggaa ggccgtcgag gaaatcaaaa ccctggccct gggaactcag
    10741 cccgccctgt tcatgtatat cccggggtgg cccaagaatg aagatgccct gtattatctg
    10801 aagcgcgaca atgtggtgcc ggatctgccg agtcaggatg cggtgcgtga agcggtgcgc
    10861 acacatgggg ccatccgggt ggtgactgaa gaacaacatg ccgctgcgct gcagtcgcaa
    10921 gcagggttgg tcgtagggaa gctgcaggag tttcggcaac ccggtcgcaa acatctcttc
    10981 ctgctttctg tacaggaaca gacctcagct cgggtgcttt gagaggagcg agcgatgggc
    11041 cgttcgatgc caaggtagcc gctgtgtctt gttttgatcc attggccctg ttgcattctg
    11101 ccacagagcc aaggattcgc tctgtagcag tcctccccga ttccgatccc cttctcctcc
    11161 tctcgcatct ccatctctga tcttgctgta agctttcagc tgcctctgcg ccgggaagaa
    11221 ggagggctcc atccttgcac ttccgatctg gaaggcgtcg atcttgagag ggcatctgtg
    11281 ccttggcgat tccggatgag acctggtcga ttcaccctat tgagcgaagg agcgagcgtg
    11341 catccgatcc atcccatggt cgtccatttt cctattgcat tgttgttggc gagcaccctg
    11401 ttcgatgcgt tggcgtttcg gtggcggagg caccagtttc gggacaccag cttgtctctg
    11461 ctggtgctcg gcatcctggc ggccggagcg gcggtgctca ccggacattt cgccgaggag
    11521 gcggtggaac gcagcggcat cccgaaacag gccatcgaaa ttcatgagga actgggcggc
    11581 tccgtgttct gggtatttct cggcctgctc gggctgcgtc tggcctcttg ttggggttgg
    11641 atgcgtgaac agccgatgct ggtgctggtc atcggcctga gcggcgggct gttgttgttg
    11701 attgcgagtt atttcggcgg ggatctggtc tatcgattcg gtgccggcgt tctgccacga
    11761 tgagcgcggt tccaggtcgg gtgtggcctg cagcgctttc ggagggaact cacatgacga
    11821 cacgtatcgt gatgttgttg atcctgtgca tgctgcctgc cacggcccag gccgatgcat
    11881 cgttgtctcg cgcgccgtgg aaggagcggg ccgtcttgcg tacggggcaa gtcgtacagg
    11941 gagactattt tgcattcggc ccgcatgtgg aaatttccgg catcgtcaac ggcgatgtga
    12001 tcgtggcggg agccaaagtg atcctgtccg gcaccgtggc tcaggatgcc agagtcgccg
    12061 gcgctcaggt cgtcagcatc tccctaactc accgacatgt tgtatctcgg gaacgttgtt
    12121 cgtcagcgag cgacatgcca gtgatccaaa accaccaaca agactcttaa aagtatttag
    12181 ccacatcgtt gaggaagtct gcgacaacca ggcgggaatg aatgtaccga aactccccat
    12241 gatgcagcgc gatccgtccg caccgtcctc tcttcctccc gcgtaagctc ccgttgttct
    12301 gaggatctga agaaacccgc cccgagaatt tgtaactggc acccatgctg cagtgtgcgg
    12361 gatccatagg aacgtcatgt gattgcgcag gaggggaaat gatgagtcac catgagacgg
    12421 atgatcgagt gctggaagtg attgtgcggt cacaggggcg cactctcgat gatatcgtgc
    12481 tcgaatgccc ggagctcaca tggaatcaag tcttcatcgt cattgatcgg ctcagtcgag
    12541 agggggcgat ccggctgatg cctaaagagc gagggtgcta cacggtccat ctcgcgagca
    12601 atgtcttcca cgacgcgcgg cagtacgcca gagtgtgagg tgagaggacg ggggcctgaa
    12661 cgtggatgtc ttctggccca gtgttcgcgg tggtgttttc agtgctgatg cgcggaacgt
    12721 ttctgcgggc ctattgggtg actccatcac atgcgcgtgc ggagttgcac agaatgacgg
    12781 gctgttggcg ttctttccag caaggagact cgtacggagg gaaaaacttt ttagcgttaa
    12841 aggagacgct catgaaggct cagacgacac aaccgttccg ggagaagaaa ccgcacacga
    12901 tgcaggttga gcagcctaac gtgcctgtgt caactcgcaa agcagcaggt tcggcacaag
    12961 ctgcagtcga cgatttacac gcccgcatca cggcacgagc ctatgaactg tatgttgtgc
    13021 gcggctgccg aaatggctac cacctcgaag attggctgga tgcagaacga gtcattctgg
    13081 atcgcgcagt caccaaatag gatttgccgt ggcgttgacg cgccgagcaa ttcattgtct
    13141 gtcgagacaa gccagggtct ccacaaggca gtgcagccaa gaacatcacc ctgagcatta
    13201 tcaagaccaa tatcggttcc atcagcggtc acgtgtgtcc cttgcggcaa ttgctggacc
    13261 ttgcgcctta gtcacgaggt catccagtca gatcaagaaa ggtgtatttc tggggagttt
    13321 cttcacagcg tcatctcgaa attgtttcca atctccccaa tgtccaacat tgagtcgcgg
    13381 agttgatgtg acagtaactt cgtgaaattg cagtgctcaa cggctggcgc aggagacgga
    13441 gtggatcttg tcggagattc gacgtctccc aacaccgtac ccaagagagg tgtccatgga
    13501 gagccagacg gataggaacc gtcggatcgc gggcgtcgtc attcgttttc ggagctgcga
    13561 gcgtgatgag atcgttcttg aatgccgagg cctcgtgtgg aattaggtct tcctggccgt
    13621 tgatcctctc agttgaaacg gcggtgtagt accgcagttg agccgaccag gtatctacac
    13681 actgcgcgta ccagagcacg ttggagccga gcgtatgatc agcatggtcg gtggatggtg
    13741 atgagaaaca cgatgtggca aatccgcatt catgggcggg gtgggcaagg ggtcgtgacg
    13801 gcggcagaac tgctcgcgat ggcggcgttc atggacggca aatatgccca ggcctttccg
    13861 agcttcgggt cggaacggat gggagcaccg gttgtggcgt tctgccgcgt cgctgaggga
    13921 gccatccgca cgcgcgaaac ggtgacgcgc cctgatgttg tcattattca ggatccgacg
    13981 ctcctgcatc aggtcgactt gttcggaggg ctcgcccccc tcgggtttgt gttgatcaat
    14041 tcgacccaga ccctcgatgc actccacatt gaggaatttc tctcaacgct gcccctcggc
    14101 catgtgtgtg cgttctctgc cacggacctc gggctgaaat acctcaagcg acccattgcc
    14161 aatgggccac tgctgggtgc gttcgccgcg atcaccggac tgatccggct tgcctccgtg
    14221 gagtcagcga ttcagcagaa attcccaggt gcggtcgggg aggcgaatcg ggctgccgcg
    14281 cgggaagcgt ttgacgttgt caccacttct attactgaac aaaggggaat cgtacaccat
    14341 gcgcatgcag attgagggtt cccaagccgt ggctgaggct attgcactct gccaacctga
    14401 ggtcattgcg gcctatccca tttccccaca gacgcacatt gtcgaacggt tatcacgcaa
    14461 gaccaagcag ggccacatcg gacgctgcca gtttctgaac gtagaatccg agtttgccgc
    14521 cttgagtgtc ctgattggcg cctcggcttc cggcgcgagg acctacacgg cgacgagcag
    14581 tcaggggctg ctctttatgg ccgaggcggt ctacaacgta gccggactag gactcccgat
    14641 tgtcatgacc atcgccaacc gggcgatcgg cgcgccgatc aatatttgga acgatcattc
    14701 ggacagcatg gcgttgcgcg atgctgggtg gattcagttg tttgccgagg ataatcagga
    14761 cgccgtcgat ctccacattc aagcgttccg tctggccgaa tcgctgagtt gcccggtgat
    14821 ggtctgcatg gacgggtatg tgctgacgca cgcctacgaa ccagtggacg tgccggacgc
    14881 cgttcaggtg aatgcctatc ttcctcccta tgatccggta caggtccttg atcctgaacg
    14941 tccggtttcc atcggcgcca tggtggggcc ggaggcgttt accgaagtta aatatttctc
    15001 gcaccaacaa catcttcgag cgctagaggt catgccggaa ttggtggagg tcttcgagca
    15061 acattttcag cgacgatccg gcggactctg ctccgcttat cgcatggagg atgccgacat
    15121 cgcggtgatt gccatggggt cggtcatcgg aacgatcaaa gacgccgtgg acgaactgcg
    15181 aaacacaggt gtccgggtcg gctgcgtcaa aatcggatgc tatcggccct ttccgaagtt
    15241 tcaggtaagc gcactgctag aaaaaacgac gcgggtgatt gtagtggaga aagaccttgc
    15301 cgtcggcatg ggagggatcg tctctgccga cgtccaatca gcgctccaag gacggcagat
    15361 ttccgtccac accgtcattg caggattggg aggacgttcc atctccacat cttcgttgaa
    15421 gcacatgatc ctggaagctc gtgcagaacg tctgacagaa ccgtacttct tggacctcaa
    15481 caagacagtg atcgagcagg agctcgctcg acggcgcgac atccgacggg ctggtccagt
    15541 cgcggagcat atgctgcaaa ccatgaatgt gatcggaacg aaagtgagtt gatggacgag
    15601 gcgatgacga cggaacgcat aaagttttat cagaccggca ccttcacggc tgggaaccgt
    15661 ttgctcgatg aagcgacgcg gaccgtccaa tcccggttgg atcggaccaa ttcgctcaac
    15721 tccggtcacc gagcctgcca aggttgcggc gaagcgctgg gggcgcgtta cgcgctcgat
    15781 gccgccatgc gtgccagcca caatcaattg attgccgtga atgcaaccgg ctgtctggag
    15841 gtcttttcca gcccctatcc cgaaagcgct tggcaaattc cctggatgca ttcgctgttc
    15901 ggcaatgcac cggcggtggc gagcgggatc gccgcggcgc ttcgtgccaa gaggcgtgac
    15961 gacgtgacgg tgatcgcgca agggggtgac ggagcgacgg tcgacattgg gttcggttgt
    16021 ctgtccggga tgtttgagcg aaacgatgac gtcctgtatc tctgttacga caacgaagcc
    16081 tacatgaaca ccggcatcca acgctcgggg gcgacccctc cgttcgcccg aaccaacacg
    16141 acgcaagccg tgggtgagca tcccggcaac ccgattggga acgggaagaa cgtgccacgg
    16201 attgccctcg cgcatgggat cccctatgtc gcgacggcct ctgtggccga tctccatgac
    16261 ctggaacgaa aagtcacgaa ggcgatcggt gttcgcgggg ctcggtatat ccatgtgcac
    16321 gtgccttgtc cgctggggtg gggctcggac cccgcacaca cgatgaaggt ggcgcgcctg
    16381 gcggtggaat ccgggctgtt ccctctgttc gaggccgaat tcggaaaagt catctgctcc
    16441 acgccgattc gccgcaaagt tcctgtcgaa cgctatctgg agctacagac tcgattcaag
    16501 catctgttcg gtccgccgca ggacacggaa gccctcgccg cgatccaagc aatggcagat
    16561 gacaacatcg ctgtttatgg actgatggaa tagaggcacc tatggaacgc acaccatttg
    16621 ccatcacgct cgatccgaac acgagcctgg ccaaccacac gggaaactgg cgcacgatga
    16681 aaccgatcta tgtcgatcgc ttgccaccgt gcaaccacgc ctgcccggcc ggcgagaaca
    16741 ttcaggcctg gctctatcat gctgaagaag gggcctacga agaagcatgg caacagctca
    16801 tgcaggacaa cccgatgccc gcgatccacg gccgcgtctg ttatcacccc tgtgaaagcg
    16861 cctgtaatcg tgggcatatc gatgaggccg tcagcattca cgcggtggaa cggttcctgg
    16921 gtgatcaggc gatcgcgcaa gggtggcggg tggcgtgcgc tccacggacg gggaagaacg
    16981 tgttggtcat cggcgccggt ccaagcggac tctccacagc ctatcacttg gctcggatgg
    17041 ggcatcaggt caccattcat gaagccggtc cacaagctgg cggcatgatg cggtacggca
    17101 tccccaagta ccgactgccg cgtgagatcg tggatgccga agtcgcaaga attcaatcca
    17161 tgggtgtcac gattaggctg aacagccgag tcgacgatct tgaggcgacc atggcggaag
    17221 gacgattcga cgccgccttt ctcgcgcttg gcgcgcatct agcccggcgc gtcgaaattc
    17281 cgggggtcga tgccaagcgg gttctcgatg ccgtcacgtt cttgcgcgac atggaagggg
    17341 cggctcgccc caagctagga cgccgcgtcg cgatctacgg tggaggcaac acggccatcg
    17401 acgtggcacg cagtgtcgag cggttgggga tggaaccggt catcattatt taccgtcgag
    17461 atttgggcca tgcgccggcg tttgccagcg aaatcacgga agcccaggac gaaggcgtgc
    17521 agttccaatg gctacgaagg atcgcgcaag gtgacgaatc gacattgaca gtcgaggaaa
    17581 tggcactcga tgaacaaggg aaaccacaac cgaccggtcg cttcgaaagg atcgaagccg
    17641 atagcgtgat tctggcgttg gggcaacggg ccgataccgg ttttcttcgt cgggtatccg
    17701 ggttgcgtgt acgggaggac ggaaccatcg aagtggatgg gacgatgatg actggccgtc
    17761 ccggtatctt cgccggcgga gacatggtgc caggcgagca atccgtcacg gtggccaccg
    17821 gccaggggaa gaaggccgcc cgccacatcg atgcctattt gcgcggctcc gcgtacgtca
    17881 aaccggaagc tcatgagccg gcgaccttca gccgtttgaa cacctggtac tacaccgacg
    17941 cagacgcctc gaagcagccg ttactgaatc tggtgcggcg tcggtcgagt tttgatgaga
    18001 tcgtcggcgg ccttgatgcg gacaccgcgc tcttggaggc acgccgctgt ctgtcctgcg
    18061 gcaactgctt caactgtgac aactgctatg cggtgtgtcc cgacagcgcc gtgatcaagc
    18121 tcggacctgg gaagcggtat gcgatcaact acgactactg taaaggatgc gggctctgcg
    18181 cggaggaatg tccctgcggc gccatcgaca tggtgagaga agtgaaatag aggggaccga
    18241 cccgtgtatg tgatgctggg gtggcagctc ttctgccgac agaactcgca caatcgatga
    18301 gagaggatgg cagccatggc cttagcacaa cgagcatgca gcggcaccgc attggttctg
    18361 tgcgctgttc tggtcggccc ggtacatgcg gcgaaggtca gtgatgccgc cgcgacacat
    18421 gagtggatgt caacaccggt gcgaaccgcc gcagaacaga tgcttgccgc gatgcccgac
    18481 gactactaca gcatcaaggg cgtcgcggcc gagaaggcga tcgccaccgg cgtaccccac
    18541 gtgctcgatg tacgcgaacc aaacgagttt gcggttgagc atattccggg cgccaaaaac
    18601 gtcccgctcc gcagtctcat gacagccatc gacgacctcc cgggcgacaa agcggcgtca
    18661 ttgattgtct actgcaaaac cggacatcgg ggtgctatcg cgttagccgt actgaggatg
    18721 ctcggttacg cgaacgtcct gagcctctac ggtggattgg acggctggaa ggctgcgggc
    18781 ttcgccattg aaaagtagcg ccacgagaag agtggcagaa ggagttgaga catgtcgtat
    18841 accgccacca cgacccaagc cgcgatccgc tggttcgagg acattggaat cgacgatatc
    18901 ccgttggttg ggggcaagaa tgcctcgctg ggcgagatgt accgggaatt ggcctcacgg
    18961 ggcgtgaagg ttcccaatgg gtttgccatt acggccgagg cctatcgttc gtttcttcgc
    19021 acgaccgggt tggatcagcg gatcacacag ataatccgtg ggctggacac gcgcgacctg
    19081 gacaatctcc gtcagcgggg gagacagatc cgtcaggcca tgctggcggc cagtctccag
    19141 caggatctcg aacgagccat cgtagaggcc tatgaccggc tgagtgatgg gcatgttgat
    19201 ctggtggatg ttgcggtccg gagcagcgca accgcagaag accttccgga tgccagcttt
    19261 gccggccagc aggaaacgta cctcaacgtg cagggccatc aggcgctcct ggatgcctgc
    19321 aagcggtgct ttgcttcact gtttaccgac cgcgcgatct cctatcgggt cgataaggga
    19381 ttcgatcact tcaagattgc gttgtcgatc ggtgtccagc gcatggtgcg gtcggatctg
    19441 agcgcatcag ggatcatgtt ttcgatcgat acggagaccg gctttcgcga tgccgtgctg
    19501 atcaatgcct cctatggatt aggagaaaac gtcgtgcaag gggccgtgaa tcccgatgaa
    19561 tactatgtct tcaagcccac cctcaggcag ggattccggc cgatcctcca gaagatgctg
    19621 ggcagcaaag agttcaagct cgtgtacgac gtcggcggga gcaagttggt caagaatgtg
    19681 ccggttccac cagatgatcg cgccagattt gcgatcacag acgacgagat tctcacgttg
    19741 tcacgatggg cctgcatgat cgaagaccat tacagtgcca agaagggtcg gaccagcccc
    19801 atggatatgg aatgggcgaa agacgggcat acgggcgaac tctttatcgt ccaggcccgg
    19861 ccggaaaccg tgcagtcgca aaagcgccaa gactcgcttg aactgtatcg gttaggtcgg
    19921 aaaggcaagg tgctgctcac cggccgaagt gtcggcagca aaatcagcct tgggccggtt
    19981 cgcgtcgtca aacacctcca acagctgcga gatttcacga gcggcgatgt cttggtcacg
    20041 gacaagacgg atccggattg ggagccggtg atgaagaagg cgtcaggcat catcacgaat
    20101 cgcggcggca gaacatgcca tgccgccatt gtgagtcgag aactcggcgt tccggctatc
    20161 gtcggaacgg gcaatgccac ggaggtgctg cgggactgcc agatggtcac gctgtcctgt
    20221 gccgagggtg atacgggatt tgtctatgaa gaggcactcc ccttcaccgt gcagcgcgtt
    20281 gagctcagcg acctcacaag accgaggacc aagatcatga tgaacgtcgg aaacccggaa
    20341 gaggccttcg cgttgtcctt catccccaat gacggcgtcg ggctggcgag agaggagttc
    20401 atcatctcca cctatataaa ggtacatccc ctcgcactcc tcaactatga ccggttggac
    20461 gatgctgcgg tcaaggctga gatcgaccga ctgacagtgg gctacgccga caaggcccag
    20521 ttcttcgtgg acaagctggc ccaaggggtt gcgatgattg cggcagcctt ctatccaaag
    20581 gacgtcatcg tccgactcag tgacttcaaa tccaacgagt atgccagcct ggtcggggga
    20641 agaggctatg agccgactga ggagaatccc atgattggct tccgcggcgc ctctcgctac
    20701 tacgattcac gctatcaggc cgggtttgcc ttggagtgcc gtgcgatgaa gaaagtccgt
    20761 ggcgagatgg gactcaccaa cgtgaagctt atgatcccgt tctgccgcac cgtcgaagaa
    20821 gggcgactgg tccaggctga aatggcgaag catgggctta cgcgcggtga gaacgggctc
    20881 gagatctacg tcatgtgcga agttccgagc aatgtcgtgt tggcggatca gttcgctgag
    20941 gtcttcgacg gattctccat cgggtccaac gatcttaccc aattgacgct tggggtggat
    21001 cgagattccg agatcatcgc ccatctgttc gatgagcgta accaggcggt gacatcaatg
    21061 atggcatcgg tgattacaac ggccaggaag aaggggaaga agatcggcat ctgcggacag
    21121 gccccgagcg actatccaga ggtggcctcg ttcctggtcg aacaaggcat cgacagcatc
    21181 tcgctcaacc ctgacgcggt cctcaagacc acgatggcca ttctgaaact ggaacagggt
    21241 ttacagaggg gacccgcaca acgaactggc tgagacacac agggaggacg gaccgatgaa
    21301 acgaatcatc tctgatctac cccatgatcg ctatcgagaa cgaacggtct tggttcgtgt
    21361 ggacttcaac gtgcctctcg atcacggtcg gattcgggag gactaccgcc ttcggcaagc
    21421 catcccgaca atcgaatacc tctcccagcg tggcgcgaaa gtgatcctcg cctcccatct
    21481 gggaaagccc aaggggaaag tggtgccagc actgtcgctg aaaccggttg ctgatcgcct
    21541 tggacagatt ctgagagttc caacagtaaa gttcgtcgag gcggcggtcg gcgagtcggt
    21601 gaaacaaacg ctcaccacgt tgaagcctgg agaggttctg ctgctcgaga atctgcggtt
    21661 cgaaccaggc gaggaggcga atgatccggt ctttgccaag caactcgccg cactggcgga
    21721 gctctatgtg aacgatgcct ttggcacgat gcaccgggcc catgcttcga cgtacggagc
    21781 agcacaactc ttcacagacc gcctggccgg ttttctcgtg cgtaaggaaa tggatgtcct
    21841 gagtcaggtg cgcgatcgcc ccgttcgtcc cttcagggtg gtggtcggtg ggatcaagat
    21901 caaggacaag ctgtcggcgt tgaaggcgct gctgccgaag gctgatacca tccttctggg
    21961 cggcggaatc gcctatacgt tcctggctgc ccaaggcgtg gcgacgggtg attcgccggt
    22021 cgagcctgaa ttcattccct gggccaaaga cgtgctggca cagtatcgaa agcacattct
    22081 gctgccggag gaccacgtca tcgccgccaa cgcggagcag cgggacagac tgcaactcgt
    22141 ccatcgagag atccctgcag gctttatggg attggatatc ggccgcgata cgtcgctgac
    22201 cttcgcgcac gagttgctgc aaggaaccgg gaccatcttc tggaacggtc ccctcggcgc
    22261 gttcgaagtc gatgaatgtg ccgacgggac agtcgacatc gcgcgggcca tggcactggc
    22321 ccattggcgt ggcgccttca cggttgtggg aggcggcgac accgtggcgg cggtgcgaaa
    22381 agcggaagta ctggagacgg agattagcca tgtgtcaaca ggcggagggg catcgttgaa
    22441 attcatcggc ggtgaagaac tacctgggat cgccgtgctc agcgagcaat cccagtaatg
    22501 gagaaggagg gaacccatga gaaaggtcaa agtcgcagtc aatggctatg gggtgatcgg
    22561 caagcgcgtg gccgatgcgg tgaagcaaca ggaggatatg gaattagtcg gcgtggccga
    22621 tgtcgtgact gactaccgga tcaagacggc agcggtcctt gggctggata tctatgctgc
    22681 gctgccggac aaggcccagg cgatgcgcgc agccgacatc ccagtcgctg gcaccttgga
    22741 tgacttgctc cggaaggtcg acgtggtggc ggattgcaca cccaagaaaa tcggagctgc
    22801 caacaagata ctctatgagc aggcaggtgt gagggcaatc taccaggggg gcgaatcaca
    22861 tgcgctgact gggcattcct tcgtggccca ggccaattat gaaacggcca tcggtcgttc
    22921 cagcaccagg gtcgtttcat gcaacacgac ctcgattgtg cgaacgctcg gtgccctgaa
    22981 gaaggccgga ctcctcaaac gcgcgcgagg cacgctgatc cgtcgagcat cggatccatg
    23041 ggaagcgcat ctggacggca tcatgaacac cgtcattccg gaaaagacca taccgagcca
    23101 ccagggtccg gatgcgaaga ccgtcgatcc ggatttggat gtcgtgacga tcgcggccaa
    23161 agcgtcccat aacagcagcc atcttcacac ctggtgggtg gagctgaccc gttcggcgag
    23221 caaagaggaa ttgttggccg cattccgcct ggcaccacgg atcgccttca ttcgcatgca
    23281 cgagggggtg gcggcgctga atagcacgat cgagctgatg agcgacttgg gacgtcgacg
    23341 cggagatctg tgggaagtgg cgctgtggga agatgtgctc acggtgaacg ggaacgaggc
    23401 ctactacacc taccaagtgt ttaaccaagc catcgtcgtt ccggagacca tcgatgccat
    23461 tcgggccctg acgggactgg agtcacaggc agagcggtcg attcagaaaa ccgatcaggc
    23521 cttggggatc gccaaagaat ttctgagaag tagcgaacac gtgctgatgg cataagcatg
    23581 tagcctcagg aggcatgcag gcatgagacc ggggctttcg gaagccgaag ctgacaggtc
    23641 gatgcgtctg agaagtcaga tcgcatggag aaagccccaa ctcaatccag atataaggag
    23701 gagcaaacca tggcccagac catgaaagca tttgtcatga agaagctcgg ctcggtgggg
    23761 atgatggaga agccgattcc tgatctcgga ccgaatgatg cgatcgtcaa aaccacggcc
    23821 gcgctcatct gtacgtccga tgtccatacg gtcggcgggg cgatcggtga acgcaccaac
    23881 ctgaccctgg gccatgaggc cgtgggggtc atttacaaat tgggcagcgc cgtgaaggga
    23941 tttcgtgagg g
//
LOCUS       DAOQPD010000058        23126 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1056_length_23126_cov_26.452820, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000058 DAOQPD010000000
VERSION     DAOQPD010000058.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 23126)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 23126)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23126
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1056_length_23126_cov_26.452820"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(11..86)
                     /locus_tag="PK063_13080"
     tRNA            complement(11..86)
                     /locus_tag="PK063_13080"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(51..53),aa:Lys,seq:ctt)
     gene            complement(133..209)
                     /locus_tag="PK063_13085"
     tRNA            complement(133..209)
                     /locus_tag="PK063_13085"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(173..175),aa:Arg,seq:ccg)
     gene            complement(277..867)
                     /locus_tag="PK063_13090"
     CDS             complement(277..867)
                     /locus_tag="PK063_13090"
                     /inference="COORDINATES: protein motif:HMM:NF015639.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HMZ98032.1"
                     /translation="MHPPLPLFQQASHWFRRAQASLLEALPCSQGCCDCCIGIFPITQ
                     LDVLELHRGLDLLPSDRKAAIVMRAREQVAALELAFPDLRSTPNLDEWTDSNIDAIVE
                     RFADLPCPALAEDGRCSVYAFRPITCRTMGVPIESDGMVQGACRVQTAVPIIRPSPSL
                     RTDYDLLAKDEAVALSILRQAHREAGDELLLPYGFI"
     gene            complement(882..1439)
                     /locus_tag="PK063_13095"
     CDS             complement(882..1439)
                     /locus_tag="PK063_13095"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98033.1"
                     /translation="MAKELPILPSNAQPAEGTAPEAVIYSRVFCKNENAPPLRLLIEF
                     LKSRGQSPILPPDMDDSMLDEWAWVQVILGYARERKPIQVFCIRDRGTYQDLFEQEQK
                     QFREDLSSHDDLEATLAQEHVTRARFILTTRMIEADVTEEGYDFNGWILEFFQEHCNG
                     IVQIDQQGFFSPKGELIVDLSLPEE"
     gene            1736..2023
                     /locus_tag="PK063_13100"
     CDS             1736..2023
                     /locus_tag="PK063_13100"
                     /inference="COORDINATES: protein motif:HMM:NF012442.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HMZ98034.1"
                     /translation="MAKSMTKSQIADHLAGKAGITKKTAVQFLDDFAALAYREAKNAF
                     VVPGIGKLVLANRKARMGRNPQTGEPIKIPAKRVVKFRVAKMAKDSILGKK"
     gene            complement(2130..2402)
                     /locus_tag="PK063_13105"
     CDS             complement(2130..2402)
                     /locus_tag="PK063_13105"
                     /inference="COORDINATES: protein motif:HMM:NF014636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoaD/ThiS family protein"
                     /protein_id="HMZ98035.1"
                     /translation="MITITLMGQLQTTDGERDLACELPTPVTVRQVIQRQGRGLRHML
                     QLLREKKVLVTINKRIASEDSMVQDGDAVRFVGHDGAGGSGLAPSF"
     gene            2535..2906
                     /locus_tag="PK063_13110"
     CDS             2535..2906
                     /locus_tag="PK063_13110"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98036.1"
                     /translation="MPDLQFVLVVSALCTSGLETLNVPEDLRRKVFDACWALVSTDPP
                     PTIERERVLDLRSGTELTLDALVATIRQLFMEAGISTLTWDHPPSEPTRPSSPAAEPL
                     IDRLQKLYPDPPPTSDPSTRN"
     gene            3023..3580
                     /gene="rfbC"
                     /locus_tag="PK063_13115"
     CDS             3023..3580
                     /gene="rfbC"
                     /locus_tag="PK063_13115"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HMZ98037.1"
                     /translation="MQITATPLSGLFQIEPDVFGDARGKFVEIFRESRYGAAGITKPF
                     VQDNFSWSVRGTLRGLHYQLAKPQGKLVMVVKGAVYDVAVDIRQGSPTFGQSYGVELS
                     EANMRQLYIPPGFAHGFCVLSEEAGFLYKCTDVYSPPDERGIIWNDPKLAIAWPITAP
                     LLSAKDQAYKCLADMTAELPRYEAS"
     gene            3788..4240
                     /locus_tag="PK063_13120"
     CDS             3788..4240
                     /locus_tag="PK063_13120"
                     /inference="COORDINATES: protein motif:HMM:NF013629.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HMZ98038.1"
                     /translation="MSIDLREIETRFRRHAVRVTRQRAAIYAALVETTSHPSADDLYR
                     MVTRQQPMMSRNTVYYTLGVLRNAGLIREVNVGHDMARYDGNVSMHHHLICLGCGQIL
                     DVMDDELNQLHLSSGQARGFEVQGHRVEFHGYCVSCQQAERNVSPRRS"
     gene            4269..4694
                     /locus_tag="PK063_13125"
     CDS             4269..4694
                     /locus_tag="PK063_13125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HMZ98039.1"
                     /translation="MGNSLKGTKSHENLKHAFAGESQANRRYLYFARRADIEGYPDVG
                     GLFRDTSEAETGHAFGHLDFLKEVGDPATGVPIGNTEANLKSAIEGETYEYTQMYPGM
                     AKTARDEGFSELAEWFETLAKAERSHANRFTKGLDSLKQ"
     gene            4801..6087
                     /locus_tag="PK063_13130"
     CDS             4801..6087
                     /locus_tag="PK063_13130"
                     /inference="COORDINATES: protein motif:HMM:NF014774.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heterodisulfide reductase-related iron-sulfur
                     binding cluster"
                     /protein_id="HMZ98040.1"
                     /translation="MKELRLLQPIDPATLEQETLRIYDVCDGCRRCFNLCPSFNTLLD
                     RIDDYESDVTKFTPADHHRVVDECYYCKLCYNHCPYTPPHQYAIDFPLLMAVWKKRLA
                     AERGIRWRDWLLTRTDLLGRLNSALAPLVNWGLGQKWVRSLMQMVLGVHQERQVLHYQ
                     QETFARWWGRRPSRNAGATGKKVALFASCLVNYQATDVGKATVQVLEKNGIHVVLPDQ
                     SCCGMPSFDIGDTTAMVKAAEHTIASLKPWVDQGYDVVIPTPSCSLMVKREYANLVSG
                     EDATRVAGRTYDVCEYLMKLKREGSLAMDFIQKPGRVAYQVPCHLRDQNIGFKSKELM
                     ECAGAQVEVIEKCSGHDGSWSAKTEFFPLSMKIAQKAVRQVEQVPADVVASDCPLAGL
                     QLDQAGAQAHVGGKSAQHPIQVVRDAYGLPRDPRTS"
     gene            6114..6698
                     /locus_tag="PK063_13135"
     CDS             6114..6698
                     /locus_tag="PK063_13135"
                     /inference="COORDINATES: protein motif:HMM:NF023432.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3501 family protein"
                     /protein_id="HMZ98041.1"
                     /translation="MNQLTQADLLPPDEYERQREAYRQTIIDLKRRRRISIGDKITMV
                     FENRETLRFQIQEMIRVERILDPQKVQDEVDVYNALLPAPGELSATLLIELTDAETMK
                     HWLDLFMGLDHGQKLGLRAGGEIVYGEFEGGHSHETKISAVHFVRFRPTPAMVTALAD
                     PAVRAALSVRHAGYEADAEVPWTMRQEWLADLRG"
     gene            6787..7539
                     /locus_tag="PK063_13140"
     CDS             6787..7539
                     /locus_tag="PK063_13140"
                     /inference="COORDINATES: protein motif:HMM:NF013411.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase"
                     /protein_id="HMZ98042.1"
                     /translation="MASVLLNKRIEFCASHRYHKPEWDAEKNRATFGACNNDPGHGHN
                     YMLEVTVAGEVDQRTGMVVNLFDLKRVLLQVLEEFDHKHLNLDLPYFNHQIPTSENLA
                     RVLWDKLQAQQDIGTLQRLSLYEDEDLCADLTAEAGLDVASVTRRYSFTAVHEGHRGH
                     TWDLFVSVHGPIHPETGMVTDIVALDRLVKERVLVPFEGRDLRVVLGTPSVTGEYLAK
                     AVWDRIASAVPAGSLQLVKLVQTRDLFYEYAG"
     gene            complement(7657..7986)
                     /locus_tag="PK063_13145"
     CDS             complement(7657..7986)
                     /locus_tag="PK063_13145"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98043.1"
                     /translation="MTIPWTTALQVARKLLPVVIEKAPELIRTFERFRGAPPAAEPSA
                     SDSALSALQLQIDAQQRTIEQQADTIVELRATVSRIQRALTLARTFLAATISLSLAII
                     AYLLLRP"
     gene            8168..8608
                     /locus_tag="PK063_13150"
     CDS             8168..8608
                     /locus_tag="PK063_13150"
                     /inference="COORDINATES: protein motif:HMM:NF012780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HMZ98044.1"
                     /translation="MKVITGVAGNPAEGYQVVGDIVGTTIRQFKPGDSAMDVAIEMVT
                     SHVGGAPVVGEDYEFLGFINEGDVIRAIDKGMDLKQARAGDIMNSAFVGVKEDTSLGC
                     VARMFEMGFQILPVVQDGKVVRSITRHDLLRAQLGLGPSVDEGS"
     gene            8815..10065
                     /locus_tag="PK063_13155"
     CDS             8815..10065
                     /locus_tag="PK063_13155"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98045.1"
                     /translation="MMSLWEFLSQDVTLLGELHSPMLSWLGSGGLIALFMWHAGRLST
                     AISSVQTCYTRVWPTLTGLAASRKSLQNEWLTVPSLSDVKRVANQSGAQPERIDLDDL
                     HTLDKAMRREPRLEQAWLHFRKTFVVERTAWFIEPKVFATRTAAEFFPRDLLNSRLNL
                     AFYHQFPSLITGGGLLLTFLAILIGLSKLHADGSHIVGIQGLINGLAGKFLTSIVGLL
                     CANLFVLLEKSAMHRLATTQQQFVTMVDELFPRKTMEQMLENFTPGAGPTPAQSPAAV
                     GAVPGDLGDRLAGSLSDRLSPTVAALREAVEVLSRRDPGGRTGSPDRLAEELSRVMQQ
                     TMAAPIQELNQAIQTLARSVEELKQDRGVKEVSDEFEFDSLDEVPTAESEQDIQQEVE
                     PDDSMLGLRWFANWRQGASMKGAA"
     gene            10067..10819
                     /locus_tag="PK063_13160"
     CDS             10067..10819
                     /locus_tag="PK063_13160"
                     /inference="COORDINATES: protein motif:HMM:NF012894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HMZ98046.1"
                     /translation="MRANHSPESTEQSSVLTIGVTDLMTSLAVIFILLFSAYVTKVSE
                     TEPQTKVKAPVQAPERNVATSTTEDMKGMLRDHFQRFDLSLDADPTDPNIVRIVVPDA
                     LLNFEFGKGTLSSVADRFLVDAMPTYAALLCGAMRDRIDSLVIEGHTDDRGSDIYNLK
                     LSQERSLNVMVKGLEVIKDSAPWAYRCFHEKTSASGRGRQDLVMDHSRALDRDKSRRV
                     VFKIRLRSGDRPGEMSQAMRQLESPAFSSRLF"
     gene            complement(10816..11508)
                     /locus_tag="PK063_13165"
     CDS             complement(10816..11508)
                     /locus_tag="PK063_13165"
                     /inference="COORDINATES: protein motif:HMM:NF015722.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HMZ98047.1"
                     /translation="MAFIPAGEFAMGSDRGQDDEQPVHRVLVKAFYLETHEVTVARYA
                     AFLMSQKADPPFKWNEATSGAHESKPVAGVNWYDARDYCRWIGRRLPTEAEWELAARG
                     TEGRMYPWGDAQPTRSHANAGHTKWHGYDTLTNVGQFELGKTPNGVYDLAGNLWEWVA
                     DWYDATYYQFSQRENPSGPSAGPLRALRGGAWNNDAKTIRSANRAGYAPDARRNDVGF
                     RCAKDAPPSNAR"
     gene            complement(11824..12156)
                     /locus_tag="PK063_13170"
     CDS             complement(11824..12156)
                     /locus_tag="PK063_13170"
                     /inference="COORDINATES: protein motif:HMM:NF012314.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HMZ98048.1"
                     /translation="MTGTVQDVRDENYKEFTESAGAVVAYGLATCEPCKQYDPILEET
                     AAKFPTIKIGKAKMHVPGRCREIKKAHTFETYPTTHFFAQGKLLLTREGVVEPAELAA
                     LISDHLLK"
     gene            complement(12234..12704)
                     /locus_tag="PK063_13175"
     CDS             complement(12234..12704)
                     /locus_tag="PK063_13175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016209 - antioxidant activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin domain-containing protein"
                     /protein_id="HMZ98049.1"
                     /translation="MSDVAAEIKVGDTAPDFTLKDQDQKDVKLSDYRGKSNVVLAFYP
                     LDWSPVCQGENKCLTDDFPKFQGAHAELFGISCDSFFSHKAWADSLDLKHRLLSDFNR
                     EVVKKYGLYFEPLNCGKRATVIVDKNGKVAYVKVQEIKVAREDKDILAALAKLS"
     gene            complement(12862..13617)
                     /locus_tag="PK063_13180"
     CDS             complement(12862..13617)
                     /locus_tag="PK063_13180"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98050.1"
                     /translation="MKIRKKAPKPSPAKPPLYVIGYRGMPPSLGELKVWYDLHYGGPL
                     TWLEPVAEGRASASHGPWRAHVITSLPDTETAQWQQVLSWDHQELGAVSLSSATPSTI
                     ADTVLVTARLARGLTLLTQGTAFDVACHDYLNPSDWNDRPLDVFITSDHVTVQHGETD
                     DHSSEWFYTLGLTKFGLDELEVIQPRGLPERETIALLRCAADAVLRKGQNQKVGGTMD
                     LHAVAHTIRFIKHRTAAPTGRMMAFRQISTDLL"
     gene            complement(13653..15533)
                     /gene="typA"
                     /locus_tag="PK063_13185"
     CDS             complement(13653..15533)
                     /gene="typA"
                     /locus_tag="PK063_13185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HMZ98051.1"
                     /translation="MNSSAPSSTSGLHAPKGRRTDIRNIAIIAHVDHGKTTLVDAVLR
                     QTHVHRKIDDMGERIMDSMDQERERGITIRAKNASVIYKGVKINIVDTPGHADFGGEV
                     ERTLRMVDGVLILVDAKEGPMPQTTFVLRKALALGHKAIVVVNKIDRPDAVIDDVVNR
                     TFDLFVHLGANDEQLDFPIVYASAIKGIATLDLKQPGTDISPLLETILDKIPAPAINR
                     DDPFQLLVLALAQDSYKGKMGIGKIQSGSIARRQNVVTLTKDGGQVPGKISDLAVFSG
                     LERSDVDSAEAGEIVAISGLEEVNIGDTIADPGSPVALPRVTIDEPTVQMTFSVNNSP
                     FAGRDGKYLTSRHLRERLFKELETNVSLRVQETDSADRFLVAGRGELHLGVLIEQMRR
                     EGYELQISQPEVILHRDGETVTEPFEELTIQVPSEYQGPVIEEIGKRRGELRHMKLVN
                     SEGTASEMHIEYHIPTRGIIGLKNILLAKTRGTIIMHHVFSGYAPADEKALLVAPHGS
                     LVAFEAGTSTAYALFMTQERGELFIGASVEVYQGMVVGQNSRDEDLDVNVCKQKQLSN
                     MRAAGTDEALVLTPPREMSLEFAMEYIGQDELVEVTPKYLRLRKRMLNPDDRRKAKKN
                     AK"
     gene            15757..18153
                     /locus_tag="PK063_13190"
     CDS             15757..18153
                     /locus_tag="PK063_13190"
                     /inference="COORDINATES: protein motif:HMM:TIGR02074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HMZ98052.1"
                     /translation="MSELDHLLDKPEKPRRQRRWWKIILIGLLLAIVLGGGGAAGTLW
                     YFSQDLPSLDPLQNYQPSLVTRVYSDDRQVIGQFFIERRFLKPIQEMPKSLTQAVIAT
                     EDTRFFEHPGLDIVGILRAAWTNLRHGGKKVEGASTITQQLARSLFLSAERTFDRKVR
                     ELILAYKMELVLTKEQILEMYLNQIYFGQGAYGVAAAGQTYFGKELSKLTLAESAFLA
                     GLPKSPSHYSPFKAYDRAKKRQEHVLSRMAEAGFISVADRDQAIAEKLNFRRPGSEHL
                     GPYFVEYIRQLLVAKFGEAMVYKGGLEVFTTLNADMQKAAEAAVFNGLREVDKRQGWR
                     GPLRTVDVTTLEVPAPDPSVKLAEGDMMEGVVTKIAKDHVLVQIGGTTGRLSFDDMAW
                     ASKYLKGKDPTKDAVPVKNIKQLLSPGDVIEVGVKKLDKDVVHLRLEQTPVVEGALVA
                     VDPKTGAIRAMVGGYDFARSEYNRAVLARRQPGSSFKPIIYATAMNQGMSPATVVLDA
                     PVVYEQEEEDKTWKPENYGKRFHGIVSLREALIHSHNLATVRLLDKVGIRNVIDFSRT
                     VGVVSPLAADLSLALGSSSVGLMELVSVYGVFANQGVRVEPYAVASVQDSGGRTLEQA
                     AIQPRQVVSRETAYLITNMMEDVIQRGTGIAAKAVIDRPVAGKTGTTNDFTDAWFIGS
                     TPNLATGAWVGFDDRRPLGETESGAHAALPIWIAFMKEALKQLPVVPFEIPEGVMFVK
                     VDPSTALLTDQDEQRGTVELFTKGTEPTKSAGSKIDPTEFYKLDQAQESASPSPVEPQ
                     "
     gene            complement(18269..18481)
                     /gene="iscX"
                     /locus_tag="PK063_13195"
     CDS             complement(18269..18481)
                     /gene="iscX"
                     /locus_tag="PK063_13195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein IscX"
                     /protein_id="HMZ98053.1"
                     /translation="MDLKWQDAEDIAIRLVEEHPDADPLTIRFTDMHAWIVALPDFKD
                     DPKKSNEKILESIQMAWHEEYQDSRS"
     gene            complement(18504..20324)
                     /gene="dnaK"
                     /locus_tag="PK063_13200"
     CDS             complement(18504..20324)
                     /gene="dnaK"
                     /locus_tag="PK063_13200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HMZ98054.1"
                     /translation="MARIVGIDLGTTNSLVAYMDKGTPRVISARHERAMVPSVVALTD
                     NGLIVGDPAKEHLTRNPERTVYSVKRFMGKSLADVQGELAYFPYTLTEKGGVIRIQLG
                     EKSYSPPQISAMILKELKLRAEAFLGESITKAVITVPAYFNDSQRQATKDAGMIAGLE
                     VLRIINEPTAASLAYGLQKKTQGTIAVYDLGGGTFDISILKLKNGIFEVLATNGDTHL
                     GGDDFDQLIADLLLKDIRAQHGLDLSTHPDHMQAVRLQAERAKIRLSEELKTTVSLDL
                     PDGQGRFSRELTRDQLEALCIPLVERSLGPCRLALKDSGLNPTDIDEVVLVGGSTRMP
                     LVRQRVQALFGKEPHCELNPDEVVALGAAVQADILSGGTTDMLLLDVTPLSLGIETMG
                     GVMSSLIRRNTTIPASAKEMFTTYVDGQTGVDIHILQGERELAKDNRSLARFRLKVPP
                     LPAGVPRIEVTFLIDANGILNVMAKDMRTGETQSIEVKPSYGLSDQEVERMIEDSFKF
                     AADDVSARKVIEARLDAGALITTTEKSLTDGGHLVEAEEIAKIRAALSALAAAKEGTD
                     PRAIRGCMADLEQAAKGLTVAMLDDSLKQGLQGKKISDVT"
     gene            complement(20330..21046)
                     /gene="hscB"
                     /locus_tag="PK063_13205"
     CDS             complement(20330..21046)
                     /gene="hscB"
                     /locus_tag="PK063_13205"
                     /inference="COORDINATES: protein motif:HMM:TIGR00714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S protein assembly co-chaperone HscB"
                     /protein_id="HMZ98055.1"
                     /translation="MSGHTHNADDRRELQMARSMCWHCQSEMAGEYFCDRCVKVQPVS
                     KDLDYFTCFGLPRRLAIDTQVLESKFYELSRAFHPDFYQNKSDAEQSISLGNSAMLNT
                     AYRTLRDPIQRAEYLLDLEAGSVKDIRTSPPADLFEEILELQETLDEFRESDRSSEHA
                     STLRAKLHTDRTNLEERQRDMEAKLQQLFSRWDALQDRGEATEQARAERTLILKDMRD
                     ILSNRTYVKNIVNDLVATIA"
     gene            complement(21061..21420)
                     /locus_tag="PK063_13210"
     CDS             complement(21061..21420)
                     /locus_tag="PK063_13210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster assembly accessory protein"
                     /protein_id="HMZ98056.1"
                     /translation="MDVTTNTDAQAPVITLSDAALKEVKRLINVQGIEEGGLRLGVKG
                     GGCSGLSYTINFDEKIGQYDQVYDFDGVKVIVDAKSAIYLQGTQLDFQKDLMGGNFKF
                     VNPNANKTCGCGESFSA"
     gene            complement(21441..21824)
                     /gene="iscU"
                     /locus_tag="PK063_13215"
     CDS             complement(21441..21824)
                     /gene="iscU"
                     /locus_tag="PK063_13215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold IscU"
                     /protein_id="HMZ98057.1"
                     /translation="MAYSEKVVDHFNNPRNMGSFKKEEDGVGTGIVGAPECGDVMKLQ
                     IKVQNDTIVDAKFKTFGCGSAIASSSLATEWLKGKTVEEAGKIKNTDIVQELNLPPVK
                     IHCSVLAEDAIKAALADYQKKADSK"
     gene            complement(21865..23082)
                     /locus_tag="PK063_13220"
     CDS             complement(21865..23082)
                     /locus_tag="PK063_13220"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0044571 - [2Fe-2S] cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IscS subfamily cysteine desulfurase"
                     /protein_id="HMZ98058.1"
                     /translation="MKFPIYLDNHATTPMDPRVLETMLPYFTEKFGNAASRNHAFGWE
                     AEEGVETARKQIAKLIHADAKEIVFTSGATESNNLALKGVVEMYHEKGDHIITSSTEH
                     RAVLDTAKTLETKRGVKVTYLPVDKFGMVNPEDVRNAITDKTILISVMFANNEIGTIN
                     PIKEIGKIAKEKGILFHCDATQGVGKVPINVQEMGIDLMSFSAHKIYGPKGIGALYVR
                     KKNPRVRIAAQMDGGGHERGMRSGTLPVPLIVGFGKACELCEQEMAADAARLSVMRDR
                     LHATITKALEDVYLNGHPTERLPHNLNISFAYVEGESLLMGCKEIALSSGSACTSATL
                     EPSYVLRALGVGAELAHSSIRFGLGRFTLDEEVDYAAKKIIETVTKLREMSPLYEMAK
                     EGIDLKTVQWAAH"
BASE COUNT         4767 a         6323 c         6787 g         5249 t
ORIGIN      
        1 cttgaaaaaa tggtgggccg tgtaggggtc gaacctacgg cccgctgatt aagagtcagc
       61 tgctctacca actgagctaa cggccccacc ggagtgcata tgtatcgatc gtgacgtgcc
      121 tgacagagcg attggtgcgc ctgacaggat ttgaacctgt ggccctcagc tccggaggct
      181 gatgctctat ccagctgagc tacaggcgct cccgtcggtc agaccaggca ccttagcata
      241 gcgtttctgt ttctgtctag ggagttgatg cgtgagctag atgaatccgt agggaaggag
      301 cagttcgtcg ccagcctccc gatgagcttg ccgcagaatc gataacgcta cggcctcatc
      361 cttggccagt aggtcataat ccgttcgtaa gctgggggag ggccggataa tggggacggc
      421 ggtctggacc cgacaggcgc cctggaccat accatcagat tcgataggca cacccatcgt
      481 gcggcacgtg atgggtctga atgcatagac gctgcaccgt ccgtcttccg ccagggcagg
      541 acagggaagg tctgcaaagc gttcaacgat ggcatcgatg ttactatccg tccactcatc
      601 aagattcggt gtggatcgaa ggtctgggaa cgccagttca agtgcggcga cttgttctcg
      661 agcgcgcata acaatggcgg ctttgcggtc ggagggtaac aggtcgaggc cccggtgcaa
      721 ttccaggaca tcgagctgtg taatggggaa gatgccgata cagcagtcgc agcagccttg
      781 actgcagggg agggcctcaa gcaacgaggc ctgagcgcgt cggaaccagt gtgaggcttg
      841 ctgaaacagc ggcaggggcg gatgcatcgg tccccatcag gctactcttc aggcagcgaa
      901 agatcgacga tgagttctcc ctttggcgaa aaaaaccctt gttgatcgat ctgcacgatc
      961 ccgttgcagt gttcctggaa aaactccagg atccagccgt tgaaatcgta gccttcctcc
     1021 gtcacgtccg cttcaatcat gcgtgttgtt agaatgaagc gcgcgcgcgt gacatgttcc
     1081 tgcgcgagcg tggcttccag atcgtcatgg gaggacaggt cttctcgaaa ctgtttctgc
     1141 tcctgttcga agagatcctg atacgtcccg cggtcccgga tgcaaaacac ctgaattggt
     1201 ttgcgttcgc gtgcatagcc gagaatcacc tgcacccagg cccattcatc gagcatggaa
     1261 tcatccatgt cggggggaag gatcggcgat tgcccgcgcg actttaaaaa ttcgatcaac
     1321 agacgaaggg gaggggcatt ctcattttta caaaagaccc gggagtagat tactgcttca
     1381 ggtgcggtgc cttccgcagg ttgggcattc gaggggagaa tgggaagttc tttggccatg
     1441 aaaacgcctc ttgttcctaa gtatgacgct gcgccgcgat gcgtgcgtgt actgtactct
     1501 gtgatctgct tggcgcgcaa gggcgtcaaa cgcgcgtgtc gccagtctgg gccgcatgtt
     1561 tccatctgtc ggctcttgac agcccctagg gctttggata cactctcgcc ctgttttcgg
     1621 actgattctg cagaccacgc gcagatttcc ggctccacct ctgtacgtac gagtttatag
     1681 atcgcagacc gcacacgtca gttcactttc attcgttgtt caaagggagg aacgcatggc
     1741 caagtcgatg accaaatcgc agattgctga ccatcttgct ggaaaggcgg gaattacgaa
     1801 gaaaacggcc gtccaatttc tggacgattt cgccgccctc gcctatcgcg aagcgaagaa
     1861 cgccttcgtg gttcccggca tcgggaagct ggtgcttgcc aatcggaagg cgcgcatggg
     1921 ccggaacccg cagaccggtg agcccatcaa gattcctgcc aagcgcgtgg tgaagttccg
     1981 ggtcgcgaag atggccaaag attcgatcct cggaaagaag taatagatct cgttcctctg
     2041 tcgatccagg gccggtgctt tctgtaaggc accggccctt gcattatcag cagccgccac
     2101 ggaccggcgc tcagtgctgc acgctagtct tagaatgacg gagccaagcc gcttcctccg
     2161 gccccgtcat gtcccacgaa ccgcaccgcg tctccatcct ggaccatcga atcttcgctg
     2221 gcgatgcgtt tgttgatggt cacgagcacc ttcttctccc gcaggagttg gagcatgtgc
     2281 cgaaggccgc ggccctgccg ttgaattact tgccgaaccg tgacgggagt cggcaactcg
     2341 caagccaggt cgcgttcccc atccgtcgtt tgaagttgtc ccatcagcgt aatcgtaatc
     2401 atgcgacgcc tatcctctta atgatatgca actgttcctg ggggcgccgc ttgggtgtgg
     2461 atgcaaattg actccccctc gcgggcgcga ctaatattac cattatgcaa tccctcaata
     2521 tccagcgtcc ggggatgccc gaccttcaat ttgtgttggt agtctcggcc ttgtgcacgt
     2581 caggtcttga aacgttgaat gtgccggaag acctccgccg caaggtgttt gatgcctgtt
     2641 gggcgctggt cagcactgat cctccaccga ccatcgagcg ggaacgggtg ctggacttgc
     2701 gatccggcac agagctcacg ctggacgccc tggttgcgac gattcgacag ctctttatgg
     2761 aggcgggcat ttcgactttg acctgggatc atccgcccag cgagcccacg cgccccagca
     2821 gtcctgccgc agaaccgctg attgaccgtt tgcagaaact ctatcccgat cctccaccga
     2881 catcggatcc ttccacccgc aattagtcgc ataggtttcg tcgcctcccg cccttggcgt
     2941 gcgcaacacg cgatcagctt ttccccatga gaagaagagg gtatgatgcg cctgacgaac
     3001 gtccttccat tcaagagggg tcatgcagat tacagcgacg ccgctcagcg gcctgtttca
     3061 gatcgagccg gatgtcttcg gggatgcgcg tggaaagttt gtggaaattt ttcgtgagtc
     3121 gcggtatgga gcggccggaa tcaccaagcc cttcgtgcag gataactttt cctggtccgt
     3181 tcgcggcacg ttgagaggcc tgcactacca attggccaaa ccccagggga aactggtcat
     3241 ggtggtgaaa ggggcggtgt atgacgtggc ggtcgacatt cggcaaggtt cacccacttt
     3301 cggacaatca tacggggtgg aattgtcgga ggcgaacatg cggcaactgt acatcccgcc
     3361 gggctttgca catgggtttt gcgtgctcag cgaggaagcc gggtttctgt ataagtgcac
     3421 ggatgtgtat tcgccgccgg atgaacgggg tatcatctgg aacgacccga aattggcaat
     3481 cgcctggccc atcaccgccc cactcctttc agcaaaagac caagcctaca aatgcctcgc
     3541 cgacatgacg gcggagttgc cacggtacga ggcctcctag ccgagggttg ctgctcccac
     3601 ttcgctagga tgattccctt gatcgattcg atctgacgca tcatctcgtc tgctgctcct
     3661 tcacggcttc actttcaaat agctccagcg ctggcggtga tacgcctttg aaaaggcctg
     3721 cttctgtctt gctgttcggc agacctccgt gctatgtagg aatcattcct gtctagtgaa
     3781 caatgacatg agcatagatc tgcgggaaat cgagacccgt tttcgccggc atgcggtgcg
     3841 tgtcacgcgc cagcgcgcag cgatttatgc ggcgttggtc gagacgacga gccatccgag
     3901 tgccgatgat ctctatcgga tggttacacg tcaacagccg atgatgtcgc gtaataccgt
     3961 ctattacacg ctcggcgtgt tgcgaaacgc cggcttgatt cgggaagtca acgtgggtca
     4021 tgacatggcc cggtatgatg ggaacgtcag tatgcatcac catctgatct gtctgggatg
     4081 cggccagatt ctagacgtga tggacgacga attgaatcag ttacatctgt cgagcgggca
     4141 ggcgagggga tttgaggtcc aggggcatcg agtcgagttt catggatatt gtgtgagttg
     4201 tcagcaggca gagcgcaacg tgtctccacg tcgcagctag gccacgttat ttattgaagg
     4261 aggacagtat gggaaacagt ttgaagggca cgaagagtca tgaaaacttg aagcacgcgt
     4321 ttgccggcga gtcgcaagcc aaccgtcggt acctgtattt tgcgcgccga gccgatatcg
     4381 aagggtatcc cgatgtcggt gggctgttcc gtgacacgtc cgaggcagag accggccacg
     4441 catttgggca tttggatttc ctcaaagaag tcggcgatcc cgccaccggc gtgccgattg
     4501 gcaacaccga agccaatttg aaatccgcga tcgagggcga aacctacgaa tacacccaga
     4561 tgtatccggg gatggccaag acggcgcgtg acgaagggtt ctcggaattg gcggaatggt
     4621 tcgagacgtt agctaaagcc gagcggtcac atgccaaccg gtttaccaag ggcctcgata
     4681 gcctgaagca gtagtagcct gcttgcaggt tttaggcgca tcacgatcgg gtggggcgga
     4741 gcgttccgcc tcacccccct gtcgaaatct ctgggccagc gtcataagga aatcccttcc
     4801 gtgaaagaac ttcgcctact ccagccgatc gatccggcca ccctcgaaca agaaacgctg
     4861 cgaatctatg atgtctgcga cggatgccgc cgctgcttca atctttgtcc gtccttcaac
     4921 acgcttctgg accggatcga tgactacgag agtgatgtca cgaagtttac gccggccgat
     4981 caccatcgcg tcgtcgatga atgttattat tgcaaactct gctacaacca ttgcccctat
     5041 accccaccgc atcaatacgc gatcgatttt ccgctcttga tggccgtatg gaaaaaacgg
     5101 ttggccgctg agaggggaat tagatggcgg gattggttat tgaccagaac cgaccttttg
     5161 ggacgactca acagcgccct cgcaccgctc gtcaactggg ggctgggtca gaagtgggtg
     5221 agaagcctca tgcaaatggt gctgggtgtg caccaagagc ggcaggtgct gcactatcaa
     5281 caagaaacat tcgcacggtg gtggggcagg cggccgtccc ggaatgcagg ggccactggc
     5341 aaaaaagtcg ccttgttcgc tagttgtctc gtcaactacc aggcaaccga cgtcggcaag
     5401 gcgaccgtgc aggtgctgga aaaaaacggt attcacgtgg tgctgccaga tcagtcctgt
     5461 tgcgggatgc cctcctttga tatcggtgat acgaccgcga tggtgaaggc ggctgaacat
     5521 accatcgcat ctttgaagcc ctgggtcgat caaggctatg acgtggtgat tcccactccc
     5581 agctgcagtc tcatggtgaa gcgcgagtat gcgaacctcg tttccggaga agatgccaca
     5641 cgggttgcag ggcgcaccta cgatgtctgt gagtacctca tgaagcttaa gcgagaaggc
     5701 agcctcgcga tggattttat ccagaagccc ggacgggtgg cctatcaggt gccctgtcac
     5761 ttgcgagacc aaaatatcgg tttcaaatca aaggagctga tggaatgcgc cggcgcgcag
     5821 gtcgaagtga ttgaaaaatg ctccggccat gacgggtcat ggtcggccaa aacagaattt
     5881 tttccgctct cgatgaagat tgcgcagaaa gccgttcgtc aggtcgagca ggttccagcc
     5941 gatgtggtgg catccgattg tccgctcgca ggccttcagc tggatcaagc cggcgctcaa
     6001 gcccatgtcg gcgggaagtc ggcgcagcat cccatacaag tggtgcgcga cgcctatggg
     6061 ttgcccagag atccacggac ttcgtaactg agccagtgtt ggccggatag cacatgaacc
     6121 aactgacaca agcagattta cttccaccgg acgagtacga gcggcaacgc gaggcgtacc
     6181 ggcagaccat tatcgatctc aaacgccgac ggcggattag tatcggtgat aagatcacga
     6241 tggttttcga gaaccgggag acgctccgct tccagatcca ggaaatgatc cgcgtggagc
     6301 gaatcctcga tccgcaaaaa gtgcaggacg aagtagacgt ctacaatgcc ctgctgccgg
     6361 ctcccggtga attgagcgca accctcttga tcgaactgac ggatgcggag accatgaaac
     6421 attggcttga tctgtttatg gggctggacc atggtcagaa gcttgggctg cgagccggag
     6481 gagagatcgt ctacggtgag ttcgaaggcg ggcacagcca tgaaacgaaa atcagcgcgg
     6541 tgcatttcgt gcggtttcgt ccgactcctg ccatggtgac ggccctggcc gatccggctg
     6601 tgcgtgcggc gctctctgtt cgccatgccg gatacgaggc ggatgccgag gtgccctgga
     6661 cgatgcggca ggaatggttg gctgatctcc gcggctagcg agcgggtggt ctgagtttta
     6721 gactggcatt caacgaggaa ctcttgtaca taacagacag cagtgacatc cggtgtatgt
     6781 gagactatgg cttccgtcct cctgaataag cgcatcgagt tttgtgcttc ccaccgctat
     6841 cacaagccgg agtgggatgc cgaaaagaac cgtgcgacct tcggcgcgtg caataatgac
     6901 cctgggcacg ggcataacta tatgctggaa gtgaccgtcg cgggagaggt tgatcagcga
     6961 accggcatgg ttgtgaacct ctttgatctg aagcgcgtgt tgctgcaggt gctggaggaa
     7021 ttcgatcaca agcatctgaa cctggacctg ccctacttca atcaccagat tcccacttcc
     7081 gaaaacctcg cgcgtgttct ctgggataag ctgcaagccc agcaggacat cggtacgctt
     7141 cagcggttgt ctctgtatga ggatgaggat ctttgtgcag acctcacggc agaggccggc
     7201 ctggatgtgg cctctgtgac cagacggtat tcatttacgg ccgtgcacga gggccatcga
     7261 ggccatacct gggacctgtt cgtgtcggtg catgggccga ttcatcctga gaccgggatg
     7321 gtgaccgata tcgtcgcgct tgatcggctg gtaaaggaac gcgtgttggt tccattcgag
     7381 ggacgagatc ttcgcgtggt gttagggacg ccgtccgtca caggggaata ccttgccaag
     7441 gctgtatggg atcgtatcgc gtcggccgtt cctgccggca gtcttcagct cgtgaaactc
     7501 gttcaaaccc gcgatctctt ctacgaatac gcgggctagg tcacgttcct cccactacct
     7561 ctcttccgct tcgctgctcc ttacatcgac attcatcctg caccagggct cgatcagagc
     7621 gtcggtgtgg ctcgtaacct atgctatcga acgcaattag ggccggagaa gtaagtaggc
     7681 gattatggca aggctgagcg aaatcgtcgc ggcaaggaag gttctagcga gggtcaacgc
     7741 gcgctgtatt ctactgactg tggcacggag ctcgacgatc gtgtccgctt gctgctcaat
     7801 ggtacgttgc tgagcgtcga tctgtagctg aagtgctgag agtgcggaat cggaagcgga
     7861 aggctccgcc gccgggggag ccccacgaaa ccgttcgaaa gtcctgatca actccggggc
     7921 cttctcaatg accaccggca gaagctttct ggcaacttgg agagctgtgg tccagggtat
     7981 agtcatgggt gttgtgtgtc tgactgaaag agcccactcg ctctattcat gacatagcca
     8041 tgatgttgaa agctatacgg tcgcagcacg atggcggcgt atagggatct ccccagtgtc
     8101 gcgtctcgaa tgaaaggcat tagattgccg gaaacgacga ttcgtccgag taacaaggga
     8161 ggcgatcatg aaggttatta caggcgtcgc gggcaatccg gcggagggat atcaagtcgt
     8221 gggggatatt gtcggcacca cgatccggca attcaagcca ggggatagcg cgatggatgt
     8281 ggccattgaa atggtgacca gtcatgtcgg tggcgccccg gtggtaggag aagattacga
     8341 atttctcggg ttcatcaatg agggcgatgt gatccgtgcg atcgataagg gcatggatct
     8401 gaagcaggcg agagccggag acatcatgaa ttcggcattt gtgggagtca aagaggatac
     8461 gtcgctgggt tgtgtcgcgc gcatgttcga gatgggattt caaatccttc ccgtcgtgca
     8521 agacgggaaa gtggttcgat ccatcacccg ccacgatctg ttgcgggcac aactcggcct
     8581 tggtccgtca gtagacgaag gaagctaagg ggaacagagc actgcaaaaa gattcatcag
     8641 gtcggcaatt cttgccgagc cgattcgtct cgagcatcgt tctgtgagag tccggcagat
     8701 caaattctca gcgttattgg gtttttcttc aacagacatc ctggcccgaa acttgataac
     8761 acacatggtc tgaagcagtg ggccatgcgt gtttcgagcg ggaggtgctg cgccatgatg
     8821 tctctctggg aatttttaag ccaggacgtg actctcctgg gagagctcca tagcccgatg
     8881 ttaagttggc tcgggtctgg tgggctgatc gcattgttca tgtggcacgc cgggcggctc
     8941 tcgacggcca tttccagcgt gcagacctgt tatacgcgtg tctggccgac cttgacgggt
     9001 ctggcggcca gtcgaaaaag ccttcagaac gagtggctga cggtgcccag tttgagcgat
     9061 gtgaagagag tcgccaacca atccggcgcc caacccgagc gcattgatct ggacgatctc
     9121 catacgctgg acaaggccat gcgccgtgag ccgcgccttg aacaggcctg gttgcacttt
     9181 cgcaagacct tcgtcgtcga acgtacagcc tggtttatcg aaccgaaagt gtttgccaca
     9241 cgaacggcag ccgaattttt cccccgcgac ttgctgaaca gccgcctcaa tctggcgttt
     9301 tatcatcaat ttccatcatt gatcacgggc ggcggtttgc tgctcacgtt tctggccatc
     9361 ctgatcggtt taagtaagct ccatgccgac ggatcccata tcgtggggat tcaggggttg
     9421 atcaacggat tggctggaaa gtttctcacg tcgatcgtgg gattgctctg cgccaatctg
     9481 ttcgtgttgc ttgagaagtc ggcgatgcat cgattggcga cgactcaaca gcaattcgtc
     9541 acgatggtgg acgaattgtt tccccgcaaa accatggaac agatgttgga aaacttcacg
     9601 cccggagccg gtccgacgcc ggcacagtca cctgctgccg tgggcgcggt gcccggtgac
     9661 ctcggtgatc gtctggccgg gagcctcagc gatcgactca gtccgacggt tgccgctctg
     9721 agggaagcgg tagaagtgct gagcaggcgt gaccccggag gacgtacagg atctccggat
     9781 cgtctggcgg aggaactctc tcgggtgatg caacagacca tggccgcgcc gattcaggaa
     9841 ttgaatcagg ctattcagac actcgctcga tcggtagaag aactgaagca ggatcgaggc
     9901 gtcaaagagg tttcggacga gtttgaattc gactcgttgg acgaggtgcc gactgcggag
     9961 agcgagcagg atatccaaca ggaggtcgag cctgatgata gcatgctcgg gttacggtgg
    10021 tttgcgaatt ggcgacaagg ggcctctatg aagggggcgg cctgacatgc gtgccaatca
    10081 ttcgccggaa tccaccgagc agtcttcggt cctgacaatc ggggtcacag acctgatgac
    10141 gtcgctggcc gtgattttta tcctgctgtt cagcgcctac gtgaccaagg tgtccgaaac
    10201 ggaaccacaa acgaaagtga aggctcctgt tcaggcgccc gagcggaacg tcgcgacgag
    10261 cacaaccgag gatatgaagg gaatgcttcg cgatcacttt cagcggttcg atctgtcgct
    10321 ggatgccgac ccgactgatc ccaatatcgt acgaattgtc gtccccgatg ccttgttgaa
    10381 cttcgaattt ggtaagggaa cgctgtcgtc cgtcgcggat cggtttctgg tggatgcgat
    10441 gcccacctac gcggcgcttc tctgtggcgc catgcgggac cgtatcgact cgctggtcat
    10501 cgaagggcat accgatgatc gcgggtcgga catctacaat ttaaagctca gccaggaacg
    10561 atcactaaat gtgatggtga aggggcttga ggtgattaaa gactcggcgc cctgggccta
    10621 tcgctgcttt catgaaaaga cgtccgccag tggacgaggc cggcaggatc tggtgatgga
    10681 tcactcccgg gcgctcgatc gggacaaaag ccgccgggtg gtctttaaga tccgtttacg
    10741 ctccggggat cgaccggggg aaatgagtca agccatgcgg cagcttgaat ctcctgcctt
    10801 cagttcccgc ctcttctagc gcgcgttcga tggcggcgca tccttggcgc agcgaaaccc
    10861 gacatcattt cttcgcgcat cgggcgcata cccggcgcga ttggcggatc gaatggtctt
    10921 ggcatcattg ttccaagccc cgccgcgtaa tgccctgagg gggcctgctg aggggccgga
    10981 agggttttct cgctggctaa actggtagta ggtggcgtcg taccaatcgg cgacccactc
    11041 ccatagattc ccggccaggt cgtacacccc gttcggcgtt tttcccaatt caaattgccc
    11101 cacgttggtc agtgtgtcgt agccatgcca tttagtgtgc ccggcgttgg cgtggctcct
    11161 cgtgggctga gcatctcccc aggggtacat ccgtccctcg gtgccccgtg cagccagctc
    11221 ccattccgct tccgtaggca atcgtctccc gatccaccgg cagtagtcgc gcgcgtcata
    11281 ccaattgacg ccggccaccg gtttgctctc gtgggcaccg ctggtcgcct cattccattt
    11341 gaagggcggg tctgcctttt gtgacatgag aaacgcggca taccgagcga ctgtcacttc
    11401 gtgtgtctcc agatagaaag ccttgaccaa gacgcgatgt accggctgtt cgtcgtcctg
    11461 gccgcgatca cttcccatgg cgaactcgcc cgcggggatg aaggccatgg gagcgctctt
    11521 tgaagaattg attgtgacgg cgtggaattc cgtttggctg acgggaaagg cacttggcgg
    11581 ggtctcatag ccgaggctgg cctcaggaat catgagccag agcagccagg tgaaaacata
    11641 ggagagcaaa gccaatccgc gcatcggttg aaggctaatc cacagtcatt ccattcagac
    11701 agcggcttgt tacaagtcta ttgtatcgcg tctgcgtcgg gaagtgggat ggatggaacg
    11761 cggggagctg tattgtcgcg tcgacgacct gcgatcggag ctgggtgtgg ccgcgagggt
    11821 agtttacttc agcagatggt cggagattaa cgcggccagc tcggccggct cgacgactcc
    11881 ttcgcgagtc agcaacagtt tgccctgcgc gaagaagtgt gtggtggggt acgtttcaaa
    11941 cgtatgcgct ttcttgatct cgcggcaacg gccggggaca tgcatcttgg ccttgccgat
    12001 cttgatggtg ggaaattttg cggcggtttc ttccaagatg ggatcgtact gcttgcaggg
    12061 ctcgcaggtg gccagcccat aggccaccac tgcaccggca ctctcggtga attctttata
    12121 gttctcatcc cgaacatctt ggactgtgcc ggtcatgggc tctcctcgtc taggacagat
    12181 gatcgagggg agggcctcgt tatggcccta tcccctcggt ccccgtttat cgcttagctc
    12241 agtttcgcga gggcggcgag aatgtcctta tcttcccgcg cgaccttgat ttcctgaacc
    12301 ttgacgtacg ccactttgcc attcttgtcg acgatgaccg tggcgcgctt gccgcaattc
    12361 aacggctcaa aatacaatcc gtacttcttg accacttcgc ggttgaagtc ggacaagagg
    12421 cggtgcttca ggtcgagcga atccgcccag gccttgtgtg aaaagaagct gtcgcagctg
    12481 atgccgaaca gttcggcatg ggcgccctgg aacttgggga agtcatcggt caggcacttg
    12541 ttctcaccct gacagaccgg gctccagtcg agcgggtaaa acgcgagcac cacattgctc
    12601 ttcccccgat aatcgctcag cttgacgtcc ttctgatcct gatcctttaa tgtaaaatcc
    12661 ggcgcggtat cgccgacttt aatttctgca gccacatcac tcattgaaat cctcctaggt
    12721 tagacctgcg gaactgcgca aactcattcg tggtaccacg cctggaaaaa ccttgtcaac
    12781 ggggccagaa ggcctagacg gagagggtga acggcgacaa tcgattggtt tcgcaatggc
    12841 ttaggggaga actaaagcag gtcacagaag gtcggtactg atttgtcgga acgccatcat
    12901 gcggccggtt ggtgcggcgg tgcgatgctt aatgaatcga atggtgtgag cgacggcatg
    12961 gagatccatt gtgcccccta ccttctggtt ttgccccttc cgcaaaacgg cgtcggcggc
    13021 acagcgcaac agcgcgatgg tttctcgctc cgggagacct cgcggctgga tcacttccaa
    13081 ttcgtccaag ccaaatttcg taagaccgag tgtataaaac cattcggaag aatgatcgtc
    13141 ggtctcgccg tgctggacgg tgacatggtc ggaggtgata aacacatcca gcgggcggtc
    13201 gttccaatcc gagggattca gatagtcatg acaggccaca tcgaacgctg ttccttgcgt
    13261 gagcagcgtc aggccgcgag cgagtcgggc agtgaccaac acagtgtctg cgatggtgct
    13321 tggcgtggcg gaggagagag aaacggcacc cagttcttga tgatcccatg acaggacctg
    13381 ctgccattgt gcagtttcgg tatccgggag actggttatc acatgtgccc gccagggacc
    13441 gtggctcgca ctggcacggc cttctgcgac cggttccagc caggtcaggg gccctccgta
    13501 gtggaggtcg taccagacct tcagttcacc gagggacggc ggcatccctc gatatccgat
    13561 cacgtagagc ggaggctttg cgggagaagg tttcggggcc tttttccgaa tcttcatgca
    13621 gtccgcacga gcagggcggg aatcgttaga cgctacttcg cgttcttctt ggccttccgg
    13681 cggtcgtccg ggttcagcat ccgcttgcga aggcgcaaat atttcggtgt gacctcgacc
    13741 aattcgtcct ggccgatata ctccatggcg aattcgagcg acatttcccg tggcggcgtg
    13801 agcaccagcg cttcgtcggt gccggcggcg cgcatgttgc tcaactgttt ctgcttgcag
    13861 acattgacgt ccagatcttc gtcgcggctg ttttgcccga cgaccattcc ctgatagacc
    13921 tcaaccgacg cgccaatgaa cagttcgccg cgctcctgag tcatgaacag cgcatatgca
    13981 gtgctggttc cagcttcgaa ggccaccagt gagccatggg gcgccacaag caacgccttt
    14041 tcgtccgctg gagcatagcc tgaaaaaacg tggtgcataa tgatcgtgcc tcgcgtcttc
    14101 gcaagcagaa tgttcttgag gccgatgatg ccgcgtgtcg ggatgtgata ctcgatatgc
    14161 atttcgctgg cggtgccttc ggaattcacg agtttcatgt ggcggagttc accgcgccgt
    14221 tttccgattt cctcgatcac cggaccctga tattccgacg ggacctggat ggtcaattct
    14281 tcaaacggtt ccgtgacggt ctccccatcg cgatgcagaa tgacttcggg ctgggagatt
    14341 tgaagttcat acccttcgcg ccgcatctgt tcgatgagca caccaagatg aagttctcca
    14401 cgtcctgcca ccaggaatcg gtcggcgcta tcggtttcct gcacacgcaa cgaaacgttg
    14461 gtttccaatt ccttgaacaa tcgttcgcgc agatggcgtg acgtcaagta tttgccgtcg
    14521 cggccggcga agggactatt gttcacggaa aaggtcattt gcacggtcgg ttcatcgatc
    14581 gtgacgcgcg gaagcgcgac gggactgccc ggatcggcaa tcgtatcgcc gatgttcact
    14641 tcttccagtc ctgaaatggc gacgatttca ccggcttcag ccgaatccac gtcactgcgt
    14701 tcaaggccgg agaacaccgc aaggtcagaa atcttgccgg gaacctggcc gccgtccttg
    14761 gtgagcgtca ccacattttg acgtcgggcg atcgagccgg attgaatctt gccgattccc
    14821 attttccctt tatacgaatc ctgcgcaaga gccagtacca ggagttggaa cggatcgtcg
    14881 cggttaatgg ccggtgcagg gattttgtcg agaatggttt ccagcagcgg agagatgtcc
    14941 gtccccggct gtttgagatc aagggtcgcg atgcccttga tggctgaggc gtagacaatg
    15001 gggaaatcga gttgttcgtc gttggcgccc aaatgcacga ataagtcgaa cgtccggttg
    15061 acgacatcgt cgatcacggc gtcagggcga tcgatcttgt tgacgaccac gatcgcttta
    15121 tgtccgaggg ccaacgcttt tcgcaagaca aacgtggtct gcggcatggg gccttctttc
    15181 gcatcgacga ggatcagcac gccatccacc atgcggagtg tgcgctcgac ttcaccgccg
    15241 aaatcggcat gtcccggcgt atcgacaatg ttgatcttca cgcctttata aatgacgctc
    15301 gcattcttgg cacggatggt gatgccgcgc tcgcgttcct gatccatcga gtccatgatg
    15361 cgttcgccca tgtcatcgat cttacgatgc acgtgggtct gccgcagcac cgcatcgacg
    15421 agcgtggttt tcccgtggtc gacgtgcgcg atgatggcga tgttacgaat gtcggtccgg
    15481 cggcctttcg gcgcgtgcaa acctgaggtg gatgagggcg ctgagctgtt cataatctcc
    15541 aatgccgtga aagtgccaaa aaaaagacgc cttcctacga aggcgtctaa gcctatggac
    15601 tatacctgat tcaaacgact tcccgcaagc tcattgtgga atgtggaaag gaaacttctt
    15661 tcgacgacga ttcgcgcctt gcttgagttt gtccggtgcg cattgtatgg tggggttgtc
    15721 gcgggttgac ctctttcctc gcaaccatcc aacttcatgt ccgaactcga tcatttgctc
    15781 gataagccgg aaaagccacg tcgtcagcgg cggtggtgga agattatcct catcggcctg
    15841 ctgctcgcca ttgtccttgg cgggggaggg gccgcgggga ctctctggta tttttctcaa
    15901 gatctgcctt cgctcgatcc actccagaat tatcagccga gtttggtcac gcgtgtttat
    15961 tccgacgacc ggcaggtcat cgggcagttc ttcattgaac gacgctttct gaaacccatc
    16021 caggaaatgc cgaagagcct gacgcaagcc gtcattgcga ccgaagatac gcggtttttc
    16081 gaacaccccg gcctggacat cgtgggcatt cttcgcgcgg cctggacgaa cttgcgccac
    16141 ggcggcaaaa aagtggaggg cgccagcacg atcacccaac agctggcgcg gtcgctcttt
    16201 ctgtcggccg agcggacgtt cgatcgcaaa gtgcgcgagc tcatcctggc ctacaaaatg
    16261 gagctggtgc tgacgaagga acagattctg gagatgtatc tgaaccagat ctatttcggc
    16321 cagggcgcgt acggtgtagc ggcggccggg cagacctact tcgggaaaga actttcgaaa
    16381 ctcacattag ctgaatcggc gttcctcgcg gggcttccca aatcacccag ccactactca
    16441 ccgttcaaag cctatgatcg tgcgaagaag cggcaggaac atgtgctcag ccgcatggcg
    16501 gaagcggggt tcatcagtgt cgccgaccgg gatcaggcca ttgccgaaaa gctgaatttc
    16561 cgccgtcccg gcagcgaaca tcttggcccg tactttgtgg aatacatccg tcagctcctc
    16621 gtggccaagt tcggcgaagc catggtctac aagggcggat tggaagtctt taccactctg
    16681 aatgccgaca tgcagaaagc ggcagaagct gccgtgttca acggactgcg tgaagtggac
    16741 aagcgccagg gttggcgcgg cccgctccgc accgtcgatg tgaccaccct ggaagttccg
    16801 gcacccgatc cctctgtgaa gctcgccgag ggcgatatga tggaaggggt ggtgacgaaa
    16861 atcgcgaagg atcatgtgct ggtccagatt ggcgggacaa cgggccggct cagcttcgac
    16921 gatatggcct gggcctccaa atatctcaaa ggaaaagatc ccacaaaaga cgccgttcca
    16981 gtgaagaaca tcaagcaact cctttcgccc ggcgatgtga tcgaagtggg cgtcaagaag
    17041 cttgataagg atgtcgtgca tctgcggttg gagcagacgc ctgtcgtcga aggcgcgctc
    17101 gtggctgtcg atcccaaaac cggcgccatt cgcgccatgg tcggcggata tgattttgcg
    17161 cgtagcgaat acaatcgtgc cgtgcttgcg cgccgtcagc cggggtcctc attcaaaccg
    17221 attatctatg cgacggcgat gaaccagggc atgagtccgg ccacggtggt gttggatgcg
    17281 ccggtggtct atgagcaaga ggaagaggac aaaacgtgga agccggaaaa ttacggcaag
    17341 cgttttcacg gcatcgtcag cttgcgggaa gcattgatcc attcgcacaa tctcgccacg
    17401 gttcggctgc tggataaggt cgggattcga aacgtgatcg atttttcgcg caccgtgggc
    17461 gtcgtgagcc cgctcgccgc ggacctgtcg ctggcgcttg ggtcttccag tgtcggcttg
    17521 atggaactgg tttcagtcta tggggtattt gccaatcaag gcgtgcgtgt cgagccctat
    17581 gccgtggcca gcgtgcagga tagcggggga cgcacgttgg agcaggccgc cattcagccg
    17641 cggcaggtgg tatctcgtga aacagcctac ctcattacga acatgatgga ggatgtgatc
    17701 cagcgcggca cgggcattgc ggcgaaagcg gtcattgaca ggcccgtggc gggaaaaacc
    17761 ggcaccacga acgactttac cgatgcctgg ttcatcggtt cgacgcccaa tttagccacc
    17821 ggagcgtggg tagggttcga cgatcggcgc cccctgggag aaactgagtc aggcgcacat
    17881 gcagccctgc ccatttggat cgccttcatg aaggaggcgc tcaaacagtt gccggttgtg
    17941 ccgtttgaaa ttccggaggg agtcatgttc gtcaaggttg atccttcgac ggcgctcctc
    18001 accgatcaag atgaacagcg tggcacggtg gagttgttta ccaagggcac ggagccgacg
    18061 aaaagtgccg gctccaagat cgatcccacc gaattctaca agctggatca agcccaggag
    18121 agcgcttcgc cttctcccgt cgagccgcaa tagaagagcc tccagattat ctcgatcagg
    18181 ccgatccatg gcctgcgatg agccagttat gcgagcgttc tatcgacgtc cgtgaggata
    18241 tgttgatgga gcaaccgtac ggaatcgatc aggaccggga gtcctgatac tcctcgtgcc
    18301 aggccatctg gatggattcg aggattttct cgtttgattt cttgggatcg tctttgaaat
    18361 ccgggagggc gacgatccag gcgtgcatgt ccgtaaagcg gatggtcagc gggtcagcat
    18421 ccggatgctc ctcgaccagg cgaatcgcga tatcttccgc atcctgccat ttcaaatcca
    18481 tcagagctcc tcgcgtcggt gaatcaggtc acatcagaga tttttttgcc ttgaagccct
    18541 tgtttcaaag aatcgtccag catggccacg gtcaggcctt tggctgcttg ctccaggtcg
    18601 gccatacacc cgcgaatggc acgcggatct gtcccctctt tggcagccgc cagggcagac
    18661 agcgcagcgc gaatcttggc gatttcttcg gcctcgacga gatgtccgcc gtcagtcaat
    18721 gacttttcgg tcgtggtaat cagagcaccc gcatccagcc tggcttcgat cacttttctc
    18781 gcgctgacat cgtccgccgc gaatttaaag gagtcttcga tcatgcgttc gacttcttga
    18841 tccgacaatc cgtacgacgg cttgacctcg atcgactgcg tctcaccggt ccgcatgtcc
    18901 ttggccatga cgttcaaaat accattggca tcgatcagga acgtcacctc gatgcgaggc
    18961 actcctgccg gcaatggcgg aaccttgaga cgaaagcggg cgaggctccg attgtccttc
    19021 gccagttctc gttcgccctg gagaatgtgt atgtccaccc cggtttggcc gtcgacatag
    19081 gtcgtgaaca tttccttggc gctggcggga atcgttgtat tgcgtcggat caagctgctc
    19141 atgacaccgc ccatggtttc gatacctaag gacagcgggg tcacgtcgag cagcagcata
    19201 tcggtggtgc cgccgctcag aatatcggct tgtactgcag ctccgagtgc caccacttcg
    19261 tctggattca attcgcaatg cggttctttg ccgaaaagag cctgaacccg ttggcggacc
    19321 agaggcatgc gcgtggatcc gcccacgagc acgacttcgt caatgtctgt cggattcaat
    19381 ccggaatctt tcagcgccag acgacagggg cccagtgagc gctcaaccag aggaatgcag
    19441 agtgcttcga gctggtcgcg tgtgagctcg cgggagaacc ggccctgtcc atcaggaaga
    19501 tcaaggctca cggtagtctt gagctcctct gatagacgaa tcttggctcg ctcagcctgt
    19561 aagcgtacgg cctgcatatg gtctgggtgt gtgctcagat cgagtccatg ttgcgcgcga
    19621 atgtccttca ggagcagatc ggcaattaac tgatcgaaat cgtccccacc gagatgggtg
    19681 tcgccatttg tggcaaggac ctcgaagatg ccgtttttca acttcaggat cgagatatcg
    19741 aaggtgcctc cgcccaggtc gtagacggcg atggtccctt gtgttttctt ctgaaggccg
    19801 taggcaagtg aggcggcggt cggttcattg atgatgcgca agacttcgag ccccgcgatc
    19861 atgcccgcat ctttggtggc ctggcgctgg ctgtcgttga aataagccgg cacggtgatg
    19921 acggctttcg tgatgctttc tccgaggaag gcttcggcgc ggagcttgag ttccttgagt
    19981 atcatcgcgg aaatctgtgg cggggagtat gatttctcgc ccaactggat tcggatgact
    20041 ccgccctttt ctgtgagcgt gtaaggaaag taagccagtt cgccctgcac gtcagccaga
    20101 cttttcccca taaagcgttt gacggaatag accgtacgtt caggatttct ggtgagatgc
    20161 tccttggccg gatcgccgac gattagtccg ttatcggtca gcgcgacgac ggaaggaacc
    20221 atggcacgtt cgtggcgggc cgaaatgacg cgtggggttc ccttgtccat gtaggcgaca
    20281 agcgagttcg tggtaccgag atcgattccg acaatgcgtg ccatacaagt tacgcgatcg
    20341 ttgcgacgag atcgttgaca atgtttttga cataggtgcg gttcgaaaga atgtcccgca
    20401 tgtctttgag gataagcgtc cgttcagctc gcgcctgctc agtggcttcc ccgcgatctt
    20461 gcagagcatc ccagcggctg aacagctgct gcagtttggc ctccatatcc cgctgccgtt
    20521 cctcgagatt cgttcgatcg gtatggagtt tcgcgcgcag cgtcgacgcg tgttccgatg
    20581 agcgatcgct ctcgcggaac tcgtcgaggg tctcctgcag ttcaagaatt tcttcgaaca
    20641 gatccgctgg cggtgacgta cggatatctt ttaccgaacc ggcctcgaga tccagcaaat
    20701 actctgcccg ctgaatcgga tctcgtagcg tgcgataggc ggtgttcaac atggccgagt
    20761 tgccgaggct gatagactgc tccgcatcgc ttttattctg atagaaatca ggatggaatg
    20821 cccggctcaa ttcgtaaaac ttagattcca ggacttgcgt atcgatggcg aggcgccggg
    20881 ggagcccgaa gcaagtgaaa tagtcgagat ctttcgacac cggttgtact ttgacgcacc
    20941 ggtcgcaaaa gtattcgccg gccatttcag actggcaatg ccagcacatg ctgcgagcca
    21001 tttgcagttc gcggcggtcg tcggcgttat gggtatgtcc actcatctgc actcgctcgc
    21061 tcaggctgaa aacgattcgc cgcaaccgca ggttttattg gcattcggat tcacaaactt
    21121 gaaatttccg cccatcaggt ctttctgaaa gtccagttga gtcccttgca gatagatcgc
    21181 gctcttggcg tctacgatga ccttcacgcc gtcgaagtcg tacacctggt cgtactgacc
    21241 gattttttcg tcgaagttga tggtgtagct cagtccggaa cagccgccgc ctttgacgcc
    21301 taagcggagg ccgccttctt caatgccttg gacattgatc aggcgcttca cttccttcag
    21361 ggccgcatca ctcagcgtaa tcacaggggc ttgggcatcg gtattcgttg tgacatccat
    21421 agtgcgctcc ttcctgtcgg ttacttcgag tcggctttct tttgatagtc ggcaagggcc
    21481 gccttaatgg catcctcagc caagaccgaa cagtgaatct tcaccggggg caggttgagt
    21541 tcctgcacga tatcggtgtt cttgattttg cccgcttcct ccaccgtttt gcctttcagc
    21601 cactctgtgg ccaggctgga actagcgata gcggacccac acccgaaggt tttgaacttc
    21661 gcgtccacaa ttgtgtcgtt ttgaactttg atttggagct tcatgacgtc cccgcactcg
    21721 ggggcgccga cgatgcccgt acccaccccg tcttcttcct tcttgaagct gcccatattg
    21781 cggggattgt tgaaatggtc gacgactttt tcgctatagg ccatggtgtc ctccggaaaa
    21841 tatcactcag atggtggttt caaattaatg cgctgcccat tgcacggtct tcaggtcgat
    21901 gccttctttc gccatttcat agagcggcga catttcgcgc agcttggtca cagtttcgat
    21961 aatcttcttt gcggcatagt caacttcctc gtcgagcgtg aagcgcccca ggccgaatct
    22021 gatcgaagaa tgcgccaatt ccgctcccac accgagggct cgtaagacgt aggaaggttc
    22081 caacgtcgcg gaggtgcagg ctgagccgga agagagcgcg atttctttgc accccatcag
    22141 caacgattcc ccttcaacat acgcaaagga gatattcaaa ttgtgcggga gccgttccgt
    22201 cggatggcca ttcaagtaga catcctcaag cgccttggta atggtcgcat gcagccggtc
    22261 acgcatgacg gagaggcgcg cggcgtcggc cgccatttcc tgctcgcaga gctcgcaggc
    22321 ctttccgaat cccacgatca acggtacagg tagcgtgccg gatcgcatgc cacgttcatg
    22381 tccaccccca tccatttgag ccgcgatgcg gacacgggga ttcttttttc tgacatagag
    22441 cgcgccgatg cctttgggcc cgtaaatctt gtgggcgcta aacgacatga gatcgatgcc
    22501 catctcctgc acattgatgg ggaccttacc tacgccctgg gttgcatcgc agtgaaaaag
    22561 gatgcctttt tctttcgcga tcttcccgat ttccttgatc gggttgatcg tcccgatttc
    22621 attattggca aacatgacgg agatgagaat ggttttgtcg gtgatggcgt tacgaacgtc
    22681 ctccgggttc accattccga acttatcgac aggcagataa gtcaccttca cgccccgctt
    22741 ggtctcgagc gtcttggccg tatccagtac ggcacgatgc tcggtcgacg acgtgatgat
    22801 atggtcgccc ttctcgtggt acatctccac cacgcctttg agggcgaggt tgtttgattc
    22861 cgtggcgcca ctcgtaaaca cgatttcttt ggcatccgca tggatcaact tggcgatctg
    22921 tttgcgggcg gtttctaccc cttcctcggc ctcccatccg aacgcgtggt tccggctggc
    22981 ggcgttcccg aacttttctg tgaaataggg cagcattgtt tccagcaccc gcgggtccat
    23041 cggggtggtc gcatggttgt ccaggtagat ggggaacttc atcgctcgac tccttgttgt
    23101 tccgtcgcga cggattgaat ggtgat
//
LOCUS       DAOQPD010000059        23031 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1061_length_23031_cov_17.914868, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000059 DAOQPD010000000
VERSION     DAOQPD010000059.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 23031)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 23031)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23031
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1061_length_23031_cov_17.914868"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(20..1195)
                     /locus_tag="PK063_13225"
     CDS             complement(20..1195)
                     /locus_tag="PK063_13225"
                     /inference="COORDINATES: protein motif:HMM:NF025885.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HMZ98059.1"
                     /translation="MSDRGVLLCWHAERSGTDVLERAVRALQNRQIEITRVLYLVQAG
                     RERELPLKVGGAELNVIEVQLDDPTKHSAIYDLVRLRVLPLINGLNMQLHINVSPGTP
                     AMHSVWLILHAGGAFPEGTRLWSSQFNQETKRTRIDPVDFAVTTYLSEIHRYSQVKPN
                     LAVYEPDAKAPSRRAAFDRLARYAKVMGAPLLVLGERGTGKTRLVETIVATLKARSKV
                     VTVPCGGLDSTLAESFLFGHRKGAFTGAATDRSGVLKEADGGILFLDEVQDLPREVQR
                     KLVRVLQDRMRRYRAVGSDCEESVDVELVCASNLSIEKLREKLDADLFDRLSHLTVMI
                     PPLRECLEDVQGDWVKVWRECRQGTNVPFDPPWSEEIRTFLQQSLLPRASALAYHKG"
     gene            complement(1195..2709)
                     /locus_tag="PK063_13230"
     CDS             complement(1195..2709)
                     /locus_tag="PK063_13230"
                     /inference="COORDINATES: protein motif:HMM:NF024491.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D-like domain-containing protein"
                     /protein_id="HMZ98060.1"
                     /translation="MSVNPWKKSFSEIDDQRDIVLPPALIKRSVQANQYTETFGELFV
                     SGRNRSMASAVIDMLHQAREKVVVSSFLLADKELEDVILAVARKGVRVYVLLASEARL
                     GKEDSEGEFEKAVLAQHKEMLKSLVGYALFRSAPHFHAKLVVVDPDTNPAGILLTANL
                     TKEALERNEELAIRLTPTEVSEAVSYLKWAMWESAEHEMVDPKQHFRAVSPLGIVPHP
                     ESMASVVATTSKSNSLREMALALIKQARTSIVVSSFGWDKDHSVVRLLCERARSGIAV
                     TVLARERVSSMPALVSLAEAGAKVLIYRWLHAKAIATDGDVAMAMSANLQSDGLDHGF
                     ELGLKLSGARAAALKRCLDVWIQSAPYEVIERPKLGDLEGKVRLWRDKRLEEVDVQRR
                     SEFDLGDVVADSADQLVAPRPPKSQGGPLQVLAHEIEYRWSAVAPSAVAKAKEVRPSS
                     KNDTPSTPFRLPVLREPGGRMVVAVKSPKELSLAHEVKAESGATAIVLAQGVLH"
     gene            complement(2709..3944)
                     /locus_tag="PK063_13235"
     CDS             complement(2709..3944)
                     /locus_tag="PK063_13235"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98061.1"
                     /translation="MKIDNFGDLGGLLQAKQTAKKSRNTPATKTTNLADRSTRQQIVL
                     RRRIEVKCWRVVGDVATAKRRPELLTVLQRANELTNGTDAADAAAHLLFESVSRRAVA
                     QRLIDIAKMYGLLEEREKRYFLTELGADALKVKQIFIPEHGTWTVWASKDPLLEQPIL
                     RVEPWREPTAYEEVRGKEKKAVEKRTFESLPDWLLEYEGVATAPPGSGGGGQLILQGL
                     ERKAESVVETNASLMIEWDVSGETLSVKGRVASAEVDSTFSAEKDVLESVWIELLSRE
                     GMNHRWDADAAALRLKFNEVDLSERESMRRDMGFSSPSFGSLGIFDPMVVHDVPLQAL
                     TEADAQDWAAWRLEQRIRDYATMSRYSSWVGEAAMPFSEFEIDLPDRDSLAEKLWQER
                     QARPSSVHWNLVSAKDWGL"
     gene            complement(3934..6552)
                     /locus_tag="PK063_13240"
     CDS             complement(3934..6552)
                     /locus_tag="PK063_13240"
                     /inference="COORDINATES: protein motif:HMM:NF024486.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HMZ98062.1"
                     /translation="MAQLHYQNLDIRRPDILIKRAFYGLKPFYDFLSRTKKYMESDDA
                     VKRLAWSKSQAQEGDEASSNDGVWVQLEEPRDRPNEPDSTFMDFLDENVREVYELPEP
                     NPTEDARGVRRQMFSEGRKILIRDRDPQTLRLFLEREPKGSQLLLRPNTITLHRQMQA
                     LQALQNEPAPFHKPLLRIFEASDHAQWPSFGPKELDDWLVLTDAERPGTEEQRRFVEL
                     ALATPDFMVLEGPPGSGKTTAICELILQLAREGKRVLLCASTHVAVDNVLERLMDERN
                     PGRDLMIPVRIGDRSNVSEKARPWQFERFVKTERERILVQLRKQKALSESQKMLFEAV
                     RHEPSSIERMVLDAANLVCGTTIGILQHPDIKSGNGSSAAVFDVLIVDEASKTTFQEF
                     LVPALYAKRWVIVGDPKQLSPYVDDVGMAVNIEACLPDEELRNACIDVFKAGRGEGLK
                     KRRVAAVSIDSDKAKLAYVYQSAERTAQVVDVSDSFGLFSADVVIGTTEELERFADDL
                     PLDVATIRAPGDALDVVRRRANAWLKLNGRGREEIPEWSNEVAWRLSRSYEQRFSMGE
                     GAEVAGRRQLSTGQKLRDQIDQLLPASKQAVQPEKVWGSVNQVRRVALPSILESLRYG
                     FERGENEEVGSALTDGLPEGVIEDRHVLLSTQHRMHPDIAAFSHEHVYHKEALFTPPE
                     MIQKRNWSYSYGPRSVWRDVRGGFDGRMNSNAKEAHEVLSALKHFDDWASKNPPEDGG
                     PWTVAILTFYRGQEREVRKGLRKWSGQGGAIRHFSRSSTSTKRPYLDVELCTVDRFQG
                     HEADLVIISIASARPTSFLESPNRLNVALTRARYQRIIVGDRHAMRRAHPSLLGLLAS
                     EKNWESKIVEDAHHEN"
     gene            complement(7005..7553)
                     /locus_tag="PK063_13245"
     CDS             complement(7005..7553)
                     /locus_tag="PK063_13245"
                     /inference="COORDINATES: protein motif:HMM:NF024750.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
                     /protein_id="HMZ98063.1"
                     /translation="MLTDTTLKSLKPKDKAYKKTDRDGMYVTVSPAGTISFRYDYRLN
                     GRRETLTIGRYEAGRQSRGAKELAEVDYGAVLSLQDARALLDRARRSVEQGDSPSRAK
                     VEKRTASNEALTFDGWAQKYFEFKADPKSGAEQLADSTLAVRKSTYKRVLADKLGEVE
                     LHCDEWHFGQTGRGVPPWCHRA"
     gene            complement(8085..8501)
                     /locus_tag="PK063_13250"
     CDS             complement(8085..8501)
                     /locus_tag="PK063_13250"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98064.1"
                     /translation="MTSPPLDNLVKIGHLKAEPRNEAEVRRLLAMARTRLVDAALASL
                     SLEGRFISAYNAAHAAALAALRWHGYRSENRYTVFQCLAHTLNWPAARWRVLDAAHQK
                     RNLAEYEGYLEIDEDSVEELRRVAGALIVDAETLLA"
     gene            complement(8479..9069)
                     /locus_tag="PK063_13255"
     CDS             complement(8479..9069)
                     /locus_tag="PK063_13255"
                     /inference="COORDINATES: protein motif:HMM:NF037100.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98065.1"
                     /translation="MSITTALFSESQSRLYRWLFGEPSRSFHLSELRRLTGLGSASLQ
                     RELHKLVEAGLVNSDYVGNQRRFQANPQSPVFDELVAIARKTLGVGPLLRDALLPLRP
                     RIQAAWIYGSVAKGTDSARSDIDLMLVGEGLTLGEVFERLTPLEAEMGRKINPTCYTP
                     DEFNRRRGEPDSFVSRVLAQSILPLIGNPNDIAAAR"
     gene            complement(9168..9437)
                     /locus_tag="PK063_13260"
     CDS             complement(9168..9437)
                     /locus_tag="PK063_13260"
                     /inference="COORDINATES: protein motif:HMM:NF025120.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HMZ98066.1"
                     /translation="MAKRIVDGIEVETGSGNVFADLGLHDADKLKIKSGLVIEITRAI
                     RKLGLTQEEAGRRMGIPQPKVSAMLRGDFSDLSERKLMDCLNRLG"
     gene            complement(9719..10456)
                     /locus_tag="PK063_13265"
     CDS             complement(9719..10456)
                     /locus_tag="PK063_13265"
                     /inference="COORDINATES: protein motif:HMM:NF022898.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HMZ98067.1"
                     /translation="MTTLAQGKLKSLYARLAPGTPVTSEELVRLGVSADLAVHYARAG
                     WLVRLARGVFRRPEQALSLHPSLKLLESRVEGLHVGGKSALDWQGVRQYVAQQETLHL
                     YGWAAARLPEWFLKEFPAEYHRKRLFDEQPEALLHVLPFEGRNEAPQVSTPERALLEL
                     LSEVGVRQPLQDARELLESTYNLRGAVLQELLARCTSVKTVRLCVQLGRELSLPWMAK
                     LLPSELPTGSDRPWVSRGSHGVLVLKP"
     gene            complement(10585..11031)
                     /locus_tag="PK063_13270"
     CDS             complement(10585..11031)
                     /locus_tag="PK063_13270"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98068.1"
                     /translation="MRIVASLAFVLSHLAVPSAAAAEYANVGRLMLQAIDAPGGAARG
                     VIVGPVAKKFRDTTGSVAPVMAEVTTLKSFRQEGCKRLNVRLRQANVPTTDGKLTEFG
                     VAYELNLCRDGSPPTEGMDLEKGGKVLDSGGAGEGAGMGGQPLARP"
     gene            complement(11035..12693)
                     /locus_tag="PK063_13275"
     CDS             complement(11035..12693)
                     /locus_tag="PK063_13275"
                     /inference="COORDINATES: protein motif:HMM:NF018666.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraN"
                     /protein_id="HMZ98069.1"
                     /translation="MAIPRLVGSWLAGLLASLLLVGSAWAADCRLDSVVCKEGLTSDP
                     QYVAGQTVVVPCKTVSGYSVCLSNIGKTCWGKHKSYTCLKPNSVNYCQPFIDAQPACW
                     QTSSECAQMDTMFSSGCMKYTQTWRCNDSSMPTPANTIRLSDTYTLLSSNYDPGSCQS
                     LADNPNCSIAQSQCVSTTPSLPLPPGIDPSQVAPDGCYQKQDTYTCLTGRSDSSECDG
                     YASNPNCTLQSTSSCDPDDLINGNCVFEQRQYQCMSQPPKTSTVTDCSGQLFCQNGNC
                     FDKGYQADPDFARSIALMEAAREAGVYGSEAEIFRGFDSRCKIKLFGLANCCKKSGGG
                     GGMSNANMALGAAVQAGGFFGSPYMYDAMFASDIPWLVDRAVDAWSATAWTSTTSFYG
                     LQFSFSSTAGLQFVGFDPYSFMLSVAIMVIQEMLSCEQPEQILAMRRGQNLCVEVGTY
                     CSKKILKICMERTKSFCCYNSRLARIINEQGRAQIGKGWGGAKTPNCSGFTPTEFATI
                     DFSRIDLSEFTAEIMANVRMPDVGAMDQQMQSSIQQKVQNYYQR"
     gene            complement(12693..13706)
                     /locus_tag="PK063_13280"
     CDS             complement(12693..13706)
                     /locus_tag="PK063_13280"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98070.1"
                     /translation="MAILTLCWAGAALADMGGSFQEGKDLGGSVAEGAFAGINSGAAE
                     EKVPAYGANPAETQYYQGGQGQIAGPGIGKTQECAGYAPGSDKIANQECEAVNFLARN
                     PQIRPQFNITKNDPMVLGAKNARNNAESFFQSIGINGGTGSSTQCTTRTETTPAQYTT
                     ETCSSVKELGTQQCTMGRTVNIETDANFQCDQTVNAYENLSCDDSTLACTVTGVKLQC
                     ASTSTLCASWASSCCWINVTCNAGGSATVQHGDCCGYSYTKVVSDVSQFLSGVTYNPA
                     GAKITCTNTGSCSMTFENYYCSNPSASIGHYDNVNSFNMTTSPVFSCTEGGGCEALDA
                     RTR"
     gene            complement(13715..14446)
                     /gene="trbC"
                     /locus_tag="PK063_13285"
     CDS             complement(13715..14446)
                     /gene="trbC"
                     /locus_tag="PK063_13285"
                     /inference="COORDINATES: protein motif:HMM:TIGR02742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly protein TrbC"
                     /protein_id="HMZ98071.1"
                     /translation="MFKRRYFLLPLFLSLVSPMTPAQERFSSSERPGESRMPTAEDIA
                     KAQTRARDGMARIPQGGAQQQHGAAAMPKIESLPKPAAPAPDIATVAEKYKSLGRAAV
                     AKDRAPDLLVMVSLSMPRETLERIADQAEWAGATLVFRGLKGDSMTRMGAEIEAIVGN
                     RNVSAVVHPPAFQQFSVTRVPAVVIARPEAGNVLDNGCSQVETFVKVAGDVSLDYALE
                     YIERRSRPWAETARAFRDRIVRGIN"
     gene            complement(14450..15460)
                     /gene="traU"
                     /locus_tag="PK063_13290"
     CDS             complement(14450..15460)
                     /gene="traU"
                     /locus_tag="PK063_13290"
                     /inference="COORDINATES: protein motif:HMM:NF010297.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer pilus assembly protein TraU"
                     /protein_id="HMZ98072.1"
                     /translation="MKFASKLVATIGLLLACVTAQAATCKGKFANPITDICWSCMFPL
                     RIGGAALASLDQEDTPNPGGIACWCGNPPKVGMKVSFWEPARRVDVVREPFCMVSLGG
                     VKMDPGFDAPVASRYRRDGQDQSSFYQVHWYVDPVIYYLQAVLDNSCLENQGFDVAYL
                     TELDPLWKDDELTRILNPEVYLFGNLPARAACAADCVTATAGFPNNTFFWCAGCQGSL
                     YPLNGNVQAHVGGVQASSLEVYRIIAKLHREGLMWAASGDGGMCGYYLQPVMDKTGYK
                     YHMLYPVPQTKKIAGKCCQPLGRSTILWGAGREFPFEGEDFAYQVFRKRNCCQGALSL
                     GN"
     gene            complement(15444..16064)
                     /gene="traW"
                     /locus_tag="PK063_13295"
     CDS             complement(15444..16064)
                     /gene="traW"
                     /locus_tag="PK063_13295"
                     /inference="COORDINATES: protein motif:HMM:TIGR02743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system protein TraW"
                     /protein_id="HMZ98073.1"
                     /translation="MPCRPFISIALFLLTVSAHAEDLGAIGPTYEITERDLIEVIQDK
                     FRRMEKTGELARMQEDYKRRVVDTIEHPKPVPGIAAAQTARTFYLDPTWTLERNVVDE
                     QGNVLYPAGTRVNPFDFDRLSKTLLFFDARDKKQVAFAKRFMAESKRPVKPILIAGAP
                     LKLMREWKREVFYDQGGALSKRLAIAQSPAVVTQEGKRLRVDEVRL"
     gene            complement(16257..17048)
                     /locus_tag="PK063_13300"
     CDS             complement(16257..17048)
                     /locus_tag="PK063_13300"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98074.1"
                     /translation="MTGLLDLFKDPYERKARLIPGLLVALPLLVPLMSVYGARHPVLT
                     GVLGLLGGCGAMYALASIARGRGKKLEEMLAKEWGGMPTTIALRHRDASALDSVSKRR
                     YHDAIASKLGITMPTAEEEAADPARADDLYVGATKRLRELTRGDKSLLLKENIAYGFH
                     RNMLAMKPVGVVICMLGLIYGLVIAKVIQFVPPAFVPSNLADPGLAAVLTLLISIALL
                     AAWLLYFDKDAVRRVGFAYAERLFESLSSLPSAPRKRTTRTPTAT"
     gene            complement(17059..17967)
                     /locus_tag="PK063_13305"
     CDS             complement(17059..17967)
                     /locus_tag="PK063_13305"
                     /inference="COORDINATES: protein motif:HMM:NF024676.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HMZ98075.1"
                     /translation="MHDEHSEPAAGAGNDPRGVSWGLERRLQFIDFRLRWEGRLNRTD
                     LTDHFGLSTPQASLDIAKYTELAPTNLTYDRSSKTYVATDNFRPLYQRSSARRYLAEL
                     LATKTGILESGASFIGVAPEVDLAPSPWRALDEHTVETLVKAIRQKLTVTVSYQSMSS
                     TEPSHRQLSPHALGYDGFRWHVRAYCHKRERFSDFVLARILSLESFEPSYIDPEQDTQ
                     WHTLLTLVLAPHPQLPAATKRVLELDYGMQAGEVKLPCRQAFLYYTLRRLGLHTKESA
                     DPAAQQITLKNREELQPYIDAVGAQA"
     gene            18056..19246
                     /locus_tag="PK063_13310"
     CDS             18056..19246
                     /locus_tag="PK063_13310"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98076.1"
                     /translation="MPTTLTFFPVDNGDMTLIKFGDAAATTLLIDVNIRQDADDPDGE
                     ARDVAKDLRDRLKKDENGRPFVDAFLLSHPDQDHCRGLARHFHLGPLADYPDDEKDYK
                     DKKIVIREIWSSPIVFRRASKTHTLCDDARAFNTEARRRVKVNRERNFVVGTGDRIQI
                     MGEDIDGKTDDLGPILCKVDESFNRINGSASSFFSARLLAPIDATDNEELEECLAKNQ
                     SSVILNVTLAADAQTPDGAKFLTGGDAEVFIWNRQWERHEHESEVLEYDLLLTPHHCS
                     WRSLSYDSWSKLGEKAQVDDGARSALSQTRNGAIIVASCKPITDDDSDPPCIRAKREY
                     QSIVDDANGAFYCTGEYPKADAVEPLVITVTSQGVQPPSKREAGAKAAAVVSSARTPM
                     PHGT"
     gene            19246..21498
                     /locus_tag="PK063_13315"
     CDS             19246..21498
                     /locus_tag="PK063_13315"
                     /inference="COORDINATES: protein motif:HMM:NF025813.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HMZ98077.1"
                     /translation="MTAIDDAFDQLRRHRGLSRVGDPVEVDGAIRIEIDIPVELPSRA
                     RPAGVSATGVRAIETCTLVFPSGWPLCAPRPYLRADFPLDLPHINPHRSGQLVSPCVF
                     EGSLDELLHRFGLDAVIDQVIEWLRNAAAGMLIDHAQGWEPTRRDACPSTIVFSAERL
                     SAAAPIDGTILTTSASYATVEGGLFAFLAPGFNPWPDLVFDQTQQGEPRGKWASGHCA
                     AFVARAPIIDGQPHVVATYQPETVADLDSLLGRATALGVDRDTLARVLDDYYRRSVFD
                     PRQDMRGWTHGLYAIVVLVVQRPVALVGTPGRSIEVLPYVVRYEVDAQSPFERKASVH
                     PAFHAHALAPELLARTSGHPAQATTQKLVLLGCGSLGSKIGLHLGRAGFGGFTFVDNE
                     GMSPHNLARHALVDEMSGLLPPNKAEQMKAAFAKLSHADARAVDGDAVSVLSDAARFA
                     DVVPDDATLILDATASLQVLAAASKAAPLAGCSARLARAAMYGQGRCAVLMLEGPGRT
                     VRVDDLAALLFEHCRVNPEVRVAIAGDSTEPTRVFVGDNCRSLTTPISDAVVSRSAAP
                     MAIQIERWLVGGLPLSGQLCIGVADAAALGMSWTTVATSPVTVVSVTEDGGWDVRILP
                     AVAEAIDADARYWGASETGGALIGRISYECRTITITGLVDAPPDSVRGSARFILGTSG
                     LVQNLRRAHADSLGYLMFVGTWHSHPLGGPHSGIDRETLRSIARDAGGLPAVSLVWTP
                     TGLRCAIDRW"
     gene            21511..22413
                     /locus_tag="PK063_13320"
     CDS             21511..22413
                     /locus_tag="PK063_13320"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98078.1"
                     /translation="MLPALELATDQMTHFPLHAGSLQIFDVDHGQCALLTMPGDSGTI
                     YRVLIDCGHAVNFQGAPWYPGAHLQSLGVSYIDMLVCTNFDEDHMSGYPDLVSRGISI
                     GCILGNPTVAPETIAKLKTRDGMGQGIEALANTLAIRRSIAWAQIPPSIPNVHMIWSW
                     NPYPYFDDENNLSLVFTLDVQGFRFMFPGDMEGNGWANLLATCPAFRPLVSGVHVLVA
                     AHHGRRNGIFEEMFDVYGCTPQLVVISDDYKQYDTQETTNYYSRKAIGITNYRGQSGV
                     RRVLTTRSDGEIRFSFLNGQCHVW"
     gene            complement(22537..23001)
                     /locus_tag="PK063_13325"
     CDS             complement(22537..23001)
                     /locus_tag="PK063_13325"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98079.1"
                     /translation="MAKHTGHENFASIRFEPIGTVDRAGEKHEFHFQTRLLGNIVALD
                     AFELRDGSPAGYRFQVVGQPSDDVFVLLGRLIEKMRRALSTQHLTDGEYGLQIADRTV
                     HGRIEWDDSAAERTPLVVVDGREISWEDFGRMLMTFEGWQFKLDISDPSEEL"
BASE COUNT         4694 a         7093 c         6447 g         4797 t
ORIGIN      
        1 gattgaaaat gctggggatt cagcctttat gataggcgag tgcggaggcc ctgggcaaca
       61 ggctctgctg aagaaatgtt ctgatttcct cagaccatgg tggatcaaaa ggaacattgg
      121 tcccttggcg gcactcccgc catactttga cccaatcccc ttgcacatct tcaagacatt
      181 cgcgcaaagg tggaatcatt actgtcagat ggctcaaccg atcaaagaga tctgcatcca
      241 gtttttcccg caatttctcg atagagagat tggatgcaca aaccaactca acatcgacac
      301 tttcctcgca atcactgccg actgcgcggt aacgcctcat gcgatcctgg agaacccgaa
      361 cgagcttacg ctgaacttct cgaggaagat cctgcacctc atccagaaac aagatcccac
      421 catcagcttc cttgagaacc cccgaacgat cagtcgcagc ccctgtaaaa gcaccttttc
      481 ggtgaccaaa cagaaaactc tctgccaacg tcgaatcgag acccccgcag ggcactgtta
      541 cgacttttga acgcgctttg agcgtcgcaa caatggtctc cactaaacga gtcttgcctg
      601 tcccgcgctc ccctagaaca agaagcggcg cccccatcac cttggcgtag cgagcaagcc
      661 tatcaaaggc tgcgcgccgg cttggagcct ttgcgtcagg ttcatagaca gccagattcg
      721 gcttaacctg gctgtatcta tgaatttcgg aaagataagt cgtaacggca aaatcaaccg
      781 ggtcgatcct cgtccgctta gtttcctgat taaactgaga tgaccagagc ctagtacctt
      841 ccgggaaagc gccgccagca tgaagaatca gccaaacgct gtgcattgcg ggcgttccgg
      901 gagagacatt aatgtgcaat tgcatgttca gcccgttgat aagcggcaga accctcagcc
      961 tgaccaaatc atagatggcg ctatgctttg tcggatcatc cagctgaacc tcgataacat
     1021 tcagttcagc cccaccgacc tttaacggaa gctctctttc tcgtccagcc tgaaccagat
     1081 agagaacgcg ggtaatttcg atctgtcgat tctggagcgc gcgtaccgca cgctccagaa
     1141 catccgtccc cgatcgctct gcatgccagc agaggagtac gcctcgatcg gacatcagtg
     1201 aagaactccc tgtgccaaaa caatggccgt cgcgccggac tcggctttga cttcatgcgc
     1261 caacgacaac tcctttggag acttcactgc cacaaccata cgaccccccg gctctctcag
     1321 cacgggcaac cgaaatggcg ttgatggcgt atcgtttttc gatgaaggtc taacttcctt
     1381 tgccttcgct accgcactag gcgccacagc agaccacctg tactcaatct catgagctag
     1441 tacctgcaat ggtcccccct gtgatttcgg aggcctgggt gcaaccagtt ggtcagcgga
     1501 gtcagccact acatcaccga gatcaaattc gcttcgacgc tgaacatcga cctcctccag
     1561 tctcttatcc cgccacagac gaaccttccc ctccagatct ccaagctttg gtctctcaat
     1621 aacttcgtac ggagctgact gaatccagac atccagacac cttttcagcg cagctgcacg
     1681 cgcgccgctc agtttcaagc ccaactcaaa cccatgatcc aagccatccg attgcaggtt
     1741 ggcggacatt gccatggcta cgtccccgtc agtcgcgatt gccttggcgt gcaaccagcg
     1801 ataaatcaga accttagcgc ctgcttcggc aagtgataca agtgcaggca tcgaggacac
     1861 gcgctcccga gccagtaccg tcaccgcaat accagatctt gcacgttcgc acagcaagcg
     1921 aactaccgaa tgatctttat cccagccaaa actgcttacg acaatggatg ttcgcgcctg
     1981 tttaatgagc gcaagtgcca tttctcgcaa tgaatttgac ttggatgttg tcgcgacaac
     2041 tgaagccata gactcaggat gcggaacgat gccgagcgga ctcactgctc ggaagtgctg
     2101 cttcgggtcc accatttcat gttcggctga ctcccacatc gcccacttca gatagctaac
     2161 agcctccgaa acctctgtgg gagtcaaacg gatagcaagc tcctcattac gttccagggc
     2221 ttccttggtc aggttcgcag tcaagagaat gcctgcggga ttggtgtctg gatcaacaac
     2281 aaccagcttt gcgtgaaaat gcggagccga acggaacaag gcataaccaa ccagagattt
     2341 cagcatctcc ttatgctgag ccaacacagc cttctcgaac tccccttcgc tatcttcttt
     2401 acccaaacga gcctcagaag ccagcaacac gtaaacacgt acgccctttc tggccacggc
     2461 cagaatgaca tcttcgagtt ccttgtctgc aagcaagaaa ctggacacaa ctactttttc
     2521 ccttgcttga tgaagcatgt cgatcactgc gctagccatc gatcgattac gcccagagac
     2581 gaacagttcg ccaaaagttt cagtgtattg gttcgcctga acacttcgtt tgatgagcgc
     2641 aggaggcaaa acgatatctc gttgatcatc gatttcagag aaagactttt tccacggatt
     2701 cacgctcatc acagccccca atcctttgca gaaaccaaat tccaatgcac cgatgacggc
     2761 cgagcttgac gctcttgcca cagcttttct gccagcgaat cacgatcagg aagatcaatc
     2821 tcaaactcag aaaatggcat cgcagcttca cctacccacg atgaatagcg agacatggtt
     2881 gcgtaatctc gaatgcgctg ctccagtcgc caggcagccc agtcttgggc atctgcctcc
     2941 gtcaacgctt gcagaggcac gtcatgtacg accatcggat caaatatgcc gagggaacca
     3001 aagctcgggc ttgagaaacc catgtcgcgg cgcatggact cgcgctctga gagatcaact
     3061 tcattgaatt tgagtctaag tgctgcggcg tcagcatccc aacgatgatt cattccttca
     3121 cggctaagta gctcaatcca gacagattcc aggacgtctt tttctgctga aaaagtcgag
     3181 tcgacttctg cgctggccac gcgccccttc acactcaaag tttccccaga cacatcccac
     3241 tcgatcatga gcgaagcatt ggtttccact acagactctg ctttccgttc caaaccctgc
     3301 agaatcaact gaccaccgcc accactccca gggggagcag tggcaacgcc ttcatattcg
     3361 agcaaccaat cagggagaga ctcaaaggtg cgtttctcaa cagccttctt ttccttgcct
     3421 cgaacctctt cgtacgcagt gggctctctc catggttcaa cacgcagaat cggctgctcc
     3481 aatagggggt ccttactcgc ccacacggtc catgtgccat gttcaggaat gaagatctgc
     3541 ttaactttga gcgcatcagc ccccaactca gtcaagaaat agcgcttctc acgctcttcg
     3601 agcagaccat acattttggc aatatcgatc agtcgctggg caaccgcgcg acgactcacg
     3661 ctctcaaaca gaagatgcgc cgcggcgtcg gcagcatccg ttccgttcgt caactcgttt
     3721 gcccgttgaa gaaccgtcaa taactcgggg cgtctttttg ccgtcgcaac atcccctacg
     3781 accctccagc atttcacctc gattcttctg cgaagaacaa tctgttgtct ggttgatcgg
     3841 tcggccaagt tggtcgtttt cgtcgcggga gtgttgcggg acttcttcgc agtttgcttt
     3901 gcctgcagca ggccaccaag gtccccaaaa ttatcaattt tcatgatgag catcctctac
     3961 gatcttgctt tcccagtttt tttctgaagc caacaaaccc aacaaacttg gatgtgctcg
     4021 tcgcatggca tgcctatccc ccacaatgat tcgttgatag cgtgcacgcg taagtgccac
     4081 attcagccgg ttcggactct ccaggaagct cgtcggcctg gcgcttgcga tagaaataat
     4141 gacgaggtcg gcctcatggc cttgaaacct atcgacagta caaagttcga catccagata
     4201 ggggcgcttt gtcgatgtgc ttgatcgtga gaagtgacgg atcgctcccc cttgccctga
     4261 ccactttcgc agccctttac gcacttcacg ctcctggcca cgatagaagg tcagaatggc
     4321 gactgtccaa ggccctccat cttccggtgg attttttgag gcccagtcgt caaagtgttt
     4381 gagtgccgaa agtacttcat gagcctcctt tgcgttggaa ttcattcgcc cgtcaaatcc
     4441 acctcttacg tcgcgccaga ctgagcgtgg accgtagctg tagctccaat tgcgtttctg
     4501 aatcatttca ggaggagtaa acagtgcttc tttgtgatag acgtgctcat gtgagaaggc
     4561 tgcgatatcc gggtgcattc tgtgctgtgt actcaaaagc acatgccgat cttcaatcac
     4621 gccctctggc aatccatcgg tcaaagcaga gccaacctcc tcattttcgc cacgctcgaa
     4681 tccatagcga agcgactcca aaatcgatgg cagggcaaca cggcggacct gattgacgct
     4741 gccccatact ttttcaggct ggacggcttg ctttgacgca ggaagcaact gatcaatctg
     4801 atcgcgcagc ttctggcccg tcgacaattg acgccgccca gcaacctcag cgccctctcc
     4861 catagaaaac cgttgttcgt aggatcgaga caaacgccaa gccacttcgt tagaccattc
     4921 ggggatttcc tcgcgccccc gcccattgag cttcagccat gcattagccc gtcgtctaac
     4981 gacatccaac gcgtcacctg gggcgcggat ggtggctaca tcgagtggaa gatcgtcagc
     5041 aaaacgttcg agttcctcgg tggtgccgat caccacgtca gctgaaaaca acccgaacga
     5101 atctgataca tcaacaacct gggcagtgcg ttcagcagac tgatacacat aggccaattt
     5161 tgccttgtca gaatcgatcg aaacggccgc cacacgccgc ttcttcaatc cctcacctcg
     5221 gcccgcctta aatacatcga tacaggcgtt tctcagttct tcatcaggca gacacgcctc
     5281 gatgttgaca gccataccaa catcatcaac atagggtgac aactgttttg ggtcacctac
     5341 gatcacccat cgtttggcgt acaacgcagg caccagaaat tcctgaaaag tggtcttcga
     5401 cgcctcatca acgatcagca catcgaaaac agctgctgag cttccattcc cgcttttaat
     5461 gtctggatgc tgaagaattc cgatggtcgt tccgcaaaca agattggcag catcaaggac
     5521 cattctttct attgaggaag gctcgtgccg taccgcttca aacagcattt tttgggattc
     5581 actcagagcc ttctgcttcc tcaactgcac taggattcgt tcacgctccg tttttacaaa
     5641 acgctcaaac tgccacggcc ttgccttctc agacacattg ctacggtctc caatcctgac
     5701 cgggatcatc aaatcacgac caggattacg ttcatccatc aggcgttcga gcacgttatc
     5761 gacagccacg tgagtagaag cacacaacag gacacgttta ccttcacgtg ccaattgcaa
     5821 gatcagctca cagatggcgg tggtttttcc tgaacccgga ggaccttcca gaaccatgaa
     5881 gtcaggcgta gccaaagcca gttccacgaa gcgtcgctgc tcctctgttc ctggacgttc
     5941 ggcgtcggtc agaaccaacc aatcgtcaag ttccttaggg ccaaacgacg gccattgcgc
     6001 atgatcactc gcctcgaaaa tacgaagcag tggcttgtga aatggagcgg gttcgttttg
     6061 cagggcttgc aaagcttgca tctggcgatg cagcgtaatc gtgtttggtc tcaacaacag
     6121 ttgagaccct tttggctcgc gctccaaaaa caggcggagg gtctggggat cacgatcacg
     6181 aattaggatc tttcgcccct ctgaaaacat ttgccgacgt acgcctctag cgtcctcagt
     6241 aggattaggc tcaggcaatt catagacttc tcgaacattc tcgtcgagaa aatccatgaa
     6301 ggtcgaatca ggctcattcg gacgatcacg aggttcttcg agctgaaccc aaaccccatc
     6361 attggatgac gcctcatcgc cttcctgggc ctggctttta gaccacgcca gccgctttac
     6421 agcatcatcg ctctccatgt acttcttggt ccgactcaaa aagtcataga agggcttcaa
     6481 tccgtaaaat gcgcgcttaa tcaggatatc cggccgccga atatccaagt tttggtagtg
     6541 cagttgtgcc ataaagctcc tcgaggttgc aattgataca acctgatatt gcaacctcta
     6601 ttccacccga ccttcacaaa tcaaaacccg cttacagagc gtgtttttga ttttatcgat
     6661 agagtacacc aggtaatttt cacccgccat tggaattatt tgcccgcaac aaacgttcgc
     6721 cactgccggt ccagtcgaat acagaagcga ccccgttagc ggttggacat cgcatcctca
     6781 aagccatttt ttttcagcca tatatcactc acgagagaag cactgacgct ggctccatca
     6841 gggcaatgcc gctctgatgt ttcttgcctt aggaggctgc cgtgacccca tcccactcac
     6901 cccgtatcgt ttcctcttca acttcattgg atggaggaac ggtccatgtc gcttaacagt
     6961 gatcacgcct ctgactacaa agaagacagc gacacttcct cacactacgc tcggtggcac
     7021 caaggcggaa cgccccttcc ggtttgcccg aaatgccatt catcgcagtg aagttcaact
     7081 tcacccagtt tgtctgccag gacgcgcttg tatgtcgatt tacgcaccgc cagggtgcta
     7141 tcggctaact gctctgcccc acttttcggg tcggccttga attcgaaata tttttgcgcc
     7201 cagccgtcaa acgtcagagc ttcatttgag gcggttcgtt tttcgacctt ggcgcgagac
     7261 ggcgaatcac cctgctctac agaccgcctt gcgcggtcca gtagcgccct tgcatcctgc
     7321 agcgacagga ctgcgccgta atcaacttcg gcgagttctt tcgcccccct gctttgccgg
     7381 ccagcctcgt accgcccaat cgtcagcgtc tcgcggcgtc cgtttaatcg gtagtcgtag
     7441 cgaaaggaga tggtgccagc tggcgagacg gtaacgtaca tgccgtctcg atccgttttc
     7501 ttgtacgcct tgtctttggg cttcagcgat ttcagcgtgg tgtcagtaag catgcgacct
     7561 ccagagcggt ccgacggttt accgtcatgc accttgacgg tcaaaaaatc gtcgacttag
     7621 gacgccgctt ctcataccgt cagattagcc gacatattac ggtagatgta cctgaacgag
     7681 attaaacgtt acaagacaat aaacaggcag agtgcaccgc ggttaagcca actctggttg
     7741 ttcagcgacg tccaaggagg tcatgttaga ttattcccac tctattgttt cctgatattt
     7801 aacagcgttg ttttgattgt ggttggtgcg ctgcaccatt tctaatacca tgaacaatac
     7861 cattgaaaaa agtcctgtgg aggtcttagg catgcatgac gtgaaaatat cgtcatcgag
     7921 ggtaacgagc ccaaatgaga ttcgctgaat gcatcttcgg cagagcaacc ctgatctcgg
     7981 acacgctctg ggccccggcg ctgagttctt gtagcgcaca atcttacccc tccgccagag
     8041 cgatcgcctt gttcgatctc gatcatctcc cacttcttct cacactacgc cagaagcgtc
     8101 tctgcatcta cgatcagagc gcctgctacg cgccgcaact cttcgaccga gtcctcgtcg
     8161 atttcaagat aaccctcata ctcggccagg ttccgcttct gatgggcagc gtcaagcacc
     8221 cgccatcggg cggcaggcca gttcagggtg tgggcaaggc actggaatac cgtgtagcgg
     8281 ttctcgctgc ggtagccgtg ccagcgcagc gctgcgagcg cagccgcatg tgcggcgttg
     8341 taggcgctga tgaagcggcc ttcgagagaa aggctggcga gcgccgcgtc gacaagccgc
     8401 gttctggcca tggcgagaag ccggcgcacc tcggcctcgt ttctcggctc ggccttcagg
     8461 tggccgatct tcaccaggtt atcgagcggc ggcgatgtca ttagggtttc caatcagggg
     8521 caggatggac tgcgccaaca ctcggctaac gaaggagtcg ggctcgccgc ggcgtcgatt
     8581 gaattcgtcc ggcgtgtaac aagtcggatt gatctttctg cccatctccg cttccaaggg
     8641 cgtcaggcgt tcgaacacct cgcccaacgt gaggccctcc ccgacgagca tcaggtcgat
     8701 gtcactcctg gccgagtcgg tgcccttggc aaccgagcca tagatccacg cggcctggat
     8761 gcgtggccgt aggggcaaga gtgcgtcgcg caacaagggc cccacgccca gggtcttgcg
     8821 cgcgatcgcc acgagctcat cgaatacggg gctttgcggg ttggcctgga agcgacgctg
     8881 gttgccaacg tagtccgagt tcaccaaccc ggcttccacg agcttgtgca gctcacgctg
     8941 gagggaggcg ctgcccagcc cggtgagtcg ccgcagctcg ctgaggtgaa agctgcggct
     9001 gggctcgccg aaaagccagc ggtagagacg cgactggctt tccgagaaca gggcagtggt
     9061 aatcgacatt gctagattct agcacagtca tgccagtttt tagcaatgcc ggggcctccc
     9121 agatggccga ccggttcagc ggccggccgc gccttgattt cgatgtccta gccgaggcgg
     9181 tttaggcagt ccatcagctt gcgttcggaa agatcggaaa agtcgccccg cagcatggcc
     9241 gacaccttgg gttgcgggat gcccatgcgc cggccggcct cctcctgtgt caggccgagc
     9301 ttgcggatcg cccgcgtgat ctcgatcacc aggccggact tgatcttgag cttatccgca
     9361 tcgtgcagac ccaagtcggc gaaaacattg ccggagccgg tctcgacttc gataccgtca
     9421 acgatgcgtt tggccattcc tcatctcctt tgcgatcgcc tcggccacct tcagccgggc
     9481 acgaatgatc tcaatgtccg atacggcgcc tcactcattg ggccgcgttt cacagaagaa
     9541 acaatcgggc aggatggccg gagcgatgta gtcgatgtcc ttcgccgaca ccccacaggc
     9601 gaaaaaggtg tcgcgccagt cacgcaccac gccgacgagc cggagcaatt ttactgcgca
     9661 gtaaataagc gcctgggcta tcagcggtgc cgcctggctg agtggccggt aggtgcgatc
     9721 acggcttgag caccagcacg ccgtggcttc cgcgcgaaac ccaggggcgg tcactgccgg
     9781 ttggcaactc gctgggaagc agcttggcca tccaagggag agacagctcg cgcccgagct
     9841 gcacgcacag gcgcacggtc ttgacgctgg tgcagcgtgc gagcagctcc tggagcacgg
     9901 ctccgcgcag gttgtaggtg ctctccaaca gctcccgggc atcctgcagc ggctggcgca
     9961 caccgacttc actcagcagt tccaacaagg cgcgctcggg tgtggagact tgcggcgcct
    10021 cgttgcggcc ttcgaacggc aggacgtgca acagggcctc cggctgctcg tcgaacaggc
    10081 gcttgcggtg atactcggcc ggaaattcct tcaggaacca ttccggcagg cgagccgcag
    10141 cccatccata gaggtgcagc gtttcctgct gcgccacata ctgacgcacc ccctgccagt
    10201 ccagggcgga cttgccgccg acgtgcaggc cttcgaccct gctctccagc agcttcaggc
    10261 tcggatggag ggacagtgct tgttcggggc gacggaaaac gcccctcgcc agccgcacca
    10321 gccatccggc acgcgcgtag tgaacagcca agtcggccga gactccgagg cgcaccagtt
    10381 cctccgaagt cacgggggtc cccggagcga gccgggcgta gagggatttt agtttgcctt
    10441 gcgctagcgt agtcacgcta cgattatctg cactttttca aaagcaggca agttttattt
    10501 gtttgccagt atcgtagtct ggctacgact attcaatcca tataaaatca cccccccgag
    10561 ctggcatctc ccaggaccga cccctcaagg gcgcgcgaga ggctggccac ccatcccggc
    10621 gccttcgccg gcaccgcccg aatccaggac tttccctccc ttttccaggt ccatcccttc
    10681 cgtcggcggg ctaccatccc tgcacaggtt cagctcatag gcgacaccga actcggtcag
    10741 cttcccatcc gtcgtgggca cattcgcttg cctcaggcgc acgttgagac gtttgcaccc
    10801 ttcctgcctg aagctcttga gggtggtgac ctcggccatg acgggagcca ccgatccggt
    10861 tgtgtccctg aacttcttcg ccaccggccc gacgatgacg ccgcgggccg ctccaccggg
    10921 cgcatcaatc gcctgcagca tcaatcgacc aacgttggca tattcggccg cggcagcact
    10981 tggcaccgcc agatgcgaga gcacgaaagc cagcgacgcg acgatcctca taccttacct
    11041 ctggtagtag ttctgaacct tctgctggat cgaggactgc atctgctggt ccatcgctcc
    11101 cacatccggc attctgacgt tggccatgat ctcggccgtg aactcggaca ggtcgatcct
    11161 ggagaagtcg atcgtcgcga attcggtcgg ggtgaagccg gagcagttcg gagttttcgc
    11221 gccgccccac cctttgccaa tctgcgccct gccctgctcg ttgatgatgc gtgccagccg
    11281 gctgttgtag cagcagaagg acttcgtcct ctccatgcag atcttcagta tcttcttgga
    11341 gcaataggtc ccgacctcca cgcagaggtt ctgccccctt cgcatcgcga ggatctgttc
    11401 gggctgctcg cacgacagca tctcctggat caccatgatc gcgacggaga gcatgaacga
    11461 gtagggatcg aacccgacga actgaaggcc ggcggtcgat gaaaagctga actggagccc
    11521 gtagaaactc gtggtcgatg tccacgcggt tgcgctccac gcatcgacgg cccggtccac
    11581 gagccacggg atgtccgacg caaacatggc gtcgtacatg tagggggaac cgaaaaaccc
    11641 tcccgcctgg acggcagcgc cgagagccat gttcgcgttg ctcatcccgc cgcctccccc
    11701 gctcttcttg cagcagttgg caaggccgaa cagcttgatc ttgcatcggg agtcgaagcc
    11761 tcggaatatc tcggcttccg agccatagac ccccgcctcc cgcgcggctt ccatgagggc
    11821 tatgcttcgg gcgaaatccg gatccgcctg gtacccctta tcgaagcagt tgccgttctg
    11881 gcagaagagt tgccccgagc aatcggtcac ggtgctcgtc tttggcggct gagacatgca
    11941 ctggtactgc ctctgctcaa agacacagtt accgttgatc agatcgtccg gatcgcagct
    12001 cgaggtcgat tggagggtgc aattcggatt cgaagcgtag ccgtcgcatt ccgacgaatc
    12061 ggaacggccc gtcagacagg tataggtgtc ctgcttctgg tagcagccgt caggtgcaac
    12121 ctgcgacgga tcgatgcccg gcggcaacgg caaggatggc gtggtcgaga cgcactggct
    12181 ctgggcgatc gagcagttgg ggttgtcggc gagggactgg cacgaccccg gatcgtagtt
    12241 gctggaaagc agggtgtagg tgtcggagag cctgatcgta ttggccggtg tcggcatgga
    12301 agagtcgttg cagcgccagg tctgcgtgta cttcatgcag ccgctggaga acatcgtgtc
    12361 catctgcgcg cactccgagc tcgtttgcca gcaggcgggc tgggcgtcga tgaagggctg
    12421 gcagtaattg accgagttcg gcttcaggca ggtgtagctc ttgtgcttgc cccagcaggt
    12481 cttgccgatg ttcgataggc agacgctgta gccgctgacc gtcttgcacg gcacgactac
    12541 cgtttgtccc gccacatatt ggggatcgct cgtcaggcct tccttgcaaa cgacggagtc
    12601 caggcgacag tcggcggccc atgccgatcc taccagcaag agcgaagcca acagacccgc
    12661 caaccagcta ccgaccagac gtggaatggc cattaccggg ttctcgcatc gagagcctcg
    12721 cagccgccgc cctccgtaca agaaaacacc gggctggtgg tcatgttgaa gctgttgacg
    12781 ttgtcgtagt ggccgatgga tgcactcggg ttcgagcagt aatagttctc gaacgtcatg
    12841 ctgcacgagc cggtgttggt gcaggtgatc ttggcgccgg ccgggttgta ggtcacgccc
    12901 gagaggaact gcgagacgtc ggaaaccacc ttcgtatagc tgtagccgca acagtcccca
    12961 tgctggaccg tggccgatcc tcccgcattg catgtcacgt tgatccagca acaactgctc
    13021 gcccatgagg cgcagagggt tgatgtgctc gcgcattgca gctttacgcc ggtcaccgtg
    13081 caggcgagcg tcgaatcgtc gcacgaaagg ttctcatagg cattcacggt ctggtcgcac
    13141 tggaagttgg cgtcggtttc aatgttgacc gttcgcccca tcgtgcattg ctgcgttccc
    13201 agttccttca cggaagagca cgtctccgtg gtgtattgcg ctggagtggt ctccgttctt
    13261 gtggtgcact gggtactgct gccagtcccg ccgttgatgc cgattgactg aaagaaactc
    13321 tccgcattgt tcctggcgtt cttggcaccg aggaccatcg ggtcgttctt ggtgatgttg
    13381 aactggggtc gaatctgggg attccgcgcc aggaagttca ccgcctcgca ttcctgattg
    13441 gcgatcttgt ccgatccggg ggcatagcct gcgcattcct gcgtcttccc gataccaggc
    13501 ccggcgatct gtccctgccc tccctggtaa tactgggtct cggcagggtt ggctccgtag
    13561 gccgggacct tctcctccgc cgcgccgctg ttgatcccgg caaacgcccc ctcggcaacc
    13621 gaaccgccca gatcctttcc ctcttggaac gaaccgccca tgtcggccag ggcggcgccg
    13681 gcccaacaca gcgtcaggat cgccactaca cgtctcaatt gatccccctg acgatcctgt
    13741 cgcggaacgc cctggcagtc tccgcccagg gccggctccg gcgctcgatg tactcgaggg
    13801 cgtagtccag ggatacatcc ccggcgacct tgacgaaggt ctccacttgc gaacagccgt
    13861 tgtcgagcac gtttccagcc tcgggacgag caatgaccac cgcgggaacc ctcgtgacgc
    13921 tgaattgctg aaatgccggc ggatggacga ctgccgaaac attgcgattc cccacgatgg
    13981 cctcgatctc cgcccccatc ctggtcatgg agtcaccttt caggccgcgg aagacgagcg
    14041 ttgcaccggc ccactccgcc tgatccgcga tacgctccaa cgtctccctc ggcatcgata
    14101 gcgacaccat gacgagcaga tccggtgcgc ggtccttggc cacggcggca cgccccaggc
    14161 tcttgtattt ctccgcgacc gtggcgatgt ccggtgcagg ggcagcaggc ttggggagcg
    14221 actcgatctt tggcatcgcc gcagccccat gctgttgctg cgctccgccc tgcgggatgc
    14281 gtgccatgcc gtcccgcgcc cttgtctgcg cctttgcgat gtcctccgcg gtcggcatgc
    14341 gcgactctcc cgggcgttcc gaagaagaga agcgttcctg cgctggcgtc atgggtgata
    14401 ccagcgacag gaacaagggg aggaggaagt agcgacgctt gaacatggct cagttcccga
    14461 ggctcagagc accctggcag caattgcgct tgcggaagac ctgataggca aagtcctcgc
    14521 cctcgaaggg gaactcgcgt ccggcacccc acaggatcgt cgagcgcccg agcggctggc
    14581 agcacttgcc cgcgatcttc ttggtctgcg gcaccggata cagcatgtgg tacttgtaac
    14641 cggtcttgtc catcacgggc tgcaggtaat agccgcacat tccgccgtca cccgaggccg
    14701 cccacatcag gccctcgcgg tgcagcttgg cgatgatccg atagacctcc aagctggaag
    14761 cctgcacgcc gcccacatgc gcttgcacgt tgccgttcaa cggatagaga ctgccctggc
    14821 aaccggcgca ccagaagaag gtgttgttgg gaaagccggc cgtcgccgtc acacaatcgg
    14881 ccgcgcatgc cgcacgcgcc ggcaggttgc cgaagaggta cacctccgga ttcagaatcc
    14941 gcgtcagctc gtcgtccttc cagagcggat cgagttcggt gagataggcg acgtcgaagc
    15001 cctggttttc caagcaactg ttgtcgagga cggcttggag gtaatagatg accggatcga
    15061 cgtaccagtg aacctggtag aaggaggact gatcctgacc gtcgcgccgg tatcgggagg
    15121 cgaccggggc gtcgaatccc ggatccatct tgacaccgcc gagactcacc atgcagaaag
    15181 gctcgcggac cacgtcgacc cggcgggcgg gctcccagaa gctgaccttc atgccgactt
    15241 tgggcggatt gccgcaccag caagctatgc cgccagggtt cggcgtgtct tcctggtcca
    15301 gggaggcaag ggccgcgcct ccgatgcgca acgggaacat gcacgaccag cagatgtcgg
    15361 tgatcgggtt ggcgaacttc cccttgcacg ttgcggcctg tgccgtcacg caggcgagaa
    15421 gcaggccgat ggtcgcaacg agcttagagg cgaacttcat cgacacggag cctcttgcct
    15481 tcctgggtta ccacggccgg ggactgggca atggcgagcc gtttggacag ggccccgccc
    15541 tggtcataga acacttccct cttccattcg cgcatcagct tgaggggcgc gccggcgatc
    15601 aggatgggtt tcaccggccg cttcgactcg gccatgaacc gcttcgcgaa cgccacctgt
    15661 ttcttgtccc gggcgtcgaa gaagagcagc gtcttgctca ggcggtcgaa gtcgaaggga
    15721 ttgacgcggg tgccggcggg gtaaaggacg ttcccctgct cgtcgaccac gttgcgctcg
    15781 agcgtccacg tcgggtcgag gtagaacgtc cgggcggtct gtgctgcggc gatacctggt
    15841 acgggcttgg ggtgctcgat ggtgtcgacg acccgccgct tgtagtcttc ctgcatccgg
    15901 gcaagctcgc ccgtcttttc catccggcgg aacttgtcct ggatgacttc gatcaggtcg
    15961 cgctcggtga tttcgtaggt cggaccgatc gcacccaggt cttcagcgtg agcactgacg
    16021 gtgagcagaa atagggcgat ggagatgaac ggtcggcatg gcatccgcgt atgctggcac
    16081 gggcgccccc ttcaatccgc aggcgaaagc gcacgttttg gcagcatttt tgcgtaggcc
    16141 gcttttcgtc cttagccgag attcatacgg catcaacaca acaactctcg gacgggaacc
    16201 gctcgaactg ccaattgcac tcaacaaggg tgttcgcgcg tggcgctcgt ttcgcgtcac
    16261 gttgccgttg gcgttcgtgt cgtgcgcttg cgaggcgcag acggcaatga cgacaggctt
    16321 tcaaacagcc gctccgcata cgcgaaaccg acgcgccgca cggcgtcctt gtcgaaatac
    16381 aacagccagg ctgccaggag tgcgatggat ataagcagtg tcagcactgc ggctaaacca
    16441 ggatccgcta ggttgctggg cacgaaggcc ggaggcacga actggatgac ctttgcgatg
    16501 accagcccgt agatcaagcc cagcatacaa atgaccacac caaccggttt catcgcgagc
    16561 atgttgcggt ggaaaccgta ggctatgttc tccttcagca gcaggctctt gtcgccgcga
    16621 gtcagctcgc gcaggcgctt cgtcgcgcca acgtagagat cgtccgccct cgccgggtct
    16681 gcggcctcct cctccgccgt cggcatcgtg atgcccaatt tggacgcgat cgcgtcgtgg
    16741 tagcggcgct tactaacgct gtccagcgcc gatgcatcac gatgacgaag cgcgatagtc
    16801 gtcggcatcc cgccccactc cttggcgagc atttcttcca acttcttgcc gcgaccgcgg
    16861 gcaatgcttg ccagcgcgta catggcgcca catccaccga gtagtccaag cacaccggtc
    16921 aggactggat ggcgcgcgcc ataaacggac atgagtggca caagaagcgg cagcgcaacg
    16981 agcagccccg ggattaggcg cgccttgcgt tcgtatgggt ctttgaaaag gtcgagcaat
    17041 ccagtcattg ggttctaatt aggcttgtgc gccaacggcg tcgatgtagg gttgaagttc
    17101 ctcgcgattc ttcagggtga tctgctgtgc ggcaggatcg gccgactcct tggtgtgcag
    17161 gccgagccgg cgcaaggtgt agtagagaaa ggcttgccga caaggtagct tcacctcgcc
    17221 cgcctgcatg ccatagtcca gctcgagcac gcgcttcgtt gctgccggta gctgagggtg
    17281 tggcgcgagg accaacgtca gcagcgtgtg ccactgggta tcctgctccg gatcgatgta
    17341 gctcggctcg aaggactcta gactcagaat tcgcgctagc acaaagtcgc tgaaccgctc
    17401 ccgcttgtgg caataggccc gcacgtgcca gcggaacccg tcgtaaccga gcgcgtgggg
    17461 cgatagctgc cgatgcgacg gctcggtcga gctcatcgac tggtagctca cagtgacagt
    17521 gagtttctgt cggatcgcct tgaccagcgt ttcgacggtg tgctcgtcca gcgcgcgcca
    17581 cggcgacggc gccaaatcca cctccggcgc tacaccgatg aagctggcac cggattcgag
    17641 gatgcccgtc tttgtggcaa ggagttcggc taggtagcgc cgtgcagagc ttcgctggta
    17701 cagcggccgg aagttgtcgg tcgcgacgta ggtctttgag ctccggtcgt aggtcaggtt
    17761 ggtaggcgcg agttcggtgt acttggcgat gtccaatgac gcttgcggcg tcgacaaccc
    17821 gaaatggtcg gtcagatcgg tccggtttag ccgcccttcc cagcgaagcc ggaagtcgat
    17881 gaactggagc cggcgctcca gcccccagct cacccctcgt ggatcattgc ccgcgccggc
    17941 ggcgggctca gagtgctcat cgtgcatgag ataagtctaa ttactagacg cgtcttgaaa
    18001 atatacgtat tataactata cgcgagtgta gctcgagtgt ccatggattc gaaaaatgcc
    18061 cactaccctg accttcttcc cggtcgacaa cggcgacatg acgctgatca agttcggcga
    18121 cgccgcggcc accactttgc taattgacgt aaatattcgg caggacgcgg acgaccccga
    18181 tggcgaggcc cgcgacgtcg ccaaggactt gcgcgaccgg ctcaagaagg acgagaacgg
    18241 tcgccccttc gtggacgcat tcctgctcag ccacccggac caggatcact gccgcggcct
    18301 ggcgcgccac tttcatctgg gtccgctggc cgactaccca gacgacgaga aggactataa
    18361 ggacaagaag atcgtgatcc gggagatctg gtcatcgccg attgtctttc gccgcgccag
    18421 caagacgcac acgctgtgcg acgatgcgcg agctttcaac accgaggcgc gtcggcgggt
    18481 caaggtgaac cgcgagagga acttcgtcgt cggcacgggc gatcggattc agatcatggg
    18541 cgaagacatc gacggcaaga ccgacgatct tgggccgatc ctatgcaagg ttgacgagag
    18601 cttcaacagg atcaatggca gtgcgtcgtc tttcttctcg gcccggctgc tggcccctat
    18661 tgatgctacc gacaacgaag agcttgaaga gtgcctggcc aagaaccaat cgagcgtgat
    18721 cctcaacgtc acactggctg ccgatgcgca gacgcccgac ggtgcgaagt tcctgactgg
    18781 cggcgacgcc gaagtcttta tctggaaccg ccagtgggaa cgccacgagc acgagtccga
    18841 ggtgctcgag tacgacctcc tgctcacccc gcatcattgc tcgtggcgct cgctgtcgta
    18901 cgacagctgg tccaagctcg gcgaaaaggc gcaggtcgac gacggcgcgc gcagcgcgct
    18961 gtcgcagacc cgcaatggcg cgatcatcgt ggcgagctgc aaaccaatta ctgacgacga
    19021 cagcgatccg ccatgcatcc gcgccaagcg cgagtaccag tccatcgtcg acgacgcaaa
    19081 tggcgctttc tattgcacgg gtgagtatcc gaaggccgac gctgttgagc cgcttgtgat
    19141 cacggtgacg tcgcagggcg tgcaaccccc ctcgaagagg gaagctggag caaaggcggc
    19201 cgcggtggtg tcgtcggcgc gcacgccgat gccgcatgga acgtgatgac agcaatcgac
    19261 gacgcgttcg accagctccg gcgccaccgc gggctctcac gggtcggtga tcccgtcgag
    19321 gtcgacggcg cgatccgaat cgagattgat atccctgtcg agttgcccag ccgagcccgg
    19381 ccggccggcg tctcggccac cggtgttcgc gcgatcgaaa cctgtacgtt ggttttcccg
    19441 agcggctggc ccctttgtgc gccgcggccc tacctgcgcg ccgacttccc gctcgacctg
    19501 ccccacatca acccgcatcg gtccggccag ctagtgtcac cgtgcgtgtt cgaaggatcg
    19561 cttgacgaac ttctccatcg ctttgggctt gatgctgtca tcgaccaggt gatcgagtgg
    19621 ctgcgcaacg cggctgcggg aatgctcatc gaccacgcgc aaggctggga gccgacacgg
    19681 cgcgacgcct gtccctcgac gatcgtgttc agtgcagaac ggctgtccgc ggccgcgcca
    19741 atcgacggga cgattctgac gaccagcgcg agctacgcca ctgtcgaggg cggcctgttc
    19801 gccttcctcg ctccaggatt caatccgtgg cccgatctcg tgttcgatca gacacagcaa
    19861 ggcgagccgc gcggcaaatg ggcgtccggg cactgcgcgg ccttcgtcgc gcgtgcgccc
    19921 attatcgacg ggcaaccgca tgttgttgcg acgtaccagc cggagacggt cgcggatctg
    19981 gattcgttgc tagggcgtgc caccgcgctt ggcgtcgatc gcgatacgct ggcacgcgta
    20041 ctcgacgact actacaggcg ttcggtcttc gacccacgac aggacatgcg ggggtggacg
    20101 catgggctgt atgcgatcgt ggtcctcgtg gtccagcggc cggtcgcgct ggtgggtacg
    20161 cccggcagga gcatcgaagt cttgccatac gtggtgcgct atgaggtcga cgcacagtct
    20221 cccttcgagc gcaaggcctc ggttcatccg gcctttcacg cccacgcgct cgcgcccgaa
    20281 ttgctcgcac gcacatccgg ccaccctgcc caggcgacca cgcagaagct ggtgctgctc
    20341 ggctgcggca gcttgggttc gaagatcggg ctgcatctcg gccgtgcagg atttgggggc
    20401 tttaccttcg tcgacaacga gggcatgtca ccgcacaacc tagcgcgtca tgcactggtc
    20461 gacgagatgt cgggcctgct gccgcccaac aaggctgagc agatgaaggc tgcgttcgcg
    20521 aagctgtcgc acgccgacgc ccgcgcagtg gacggtgatg ccgtctccgt gctatccgat
    20581 gcagctcggt tcgccgacgt cgtacccgat gacgcgacct taatcctaga tgcgactgcg
    20641 tcgctgcagg ttcttgcagc cgcctcgaag gctgcaccgt tggccggctg ctccgcccgc
    20701 cttgctcgag ccgcgatgta tggtcaaggt cgatgtgccg tgctgatgct ggaggggcca
    20761 gggcgaacgg tccgtgtcga tgacttggcc gccctcctct tcgaacactg tcgggtcaac
    20821 cccgaggtgc gcgtcgcaat cgccggcgat tcgaccgagc cgacccgcgt cttcgttgga
    20881 gacaattgcc ggtcactgac cacgccgata tccgacgcag tcgtgtcgcg gtcagcggcg
    20941 ccaatggcga tccagattga acgctggctc gttggtggcc ttccgctgtc cgggcagcta
    21001 tgcatcggcg tcgcggacgc cgcggcactc ggcatgagtt ggaccacggt cgccacctcg
    21061 ccggtgacgg tcgtttctgt gaccgaggat ggtggatggg acgttcggat tctcccggcc
    21121 gtggccgaag ccattgacgc cgatgcgcgc tactggggcg catcggaaac gggcggtgcg
    21181 ctgatcgggc ggatctcata cgaatgccgg acgatcacaa tcaccggtct tgtcgacgcc
    21241 ccacccgaca gtgtccgtgg cagtgcccgc ttcatcctcg gtaccagcgg gctggtccag
    21301 aatctgcgcc gcgcgcacgc cgacagcctc ggatatctca tgtttgtcgg cacttggcac
    21361 agccatccgc ttggcgggcc acattcgggc attgatcgcg aaacgttaag gtcgattgcc
    21421 agagacgctg gcggactgcc ggctgtgtcg ctggtctgga ctccaaccgg cctgcgctgc
    21481 gcaatcgacc gctggtgatc acgaggggac atgcttccgg ccttagaact tgcgaccgac
    21541 caaatgacgc atttcccgtt gcacgctggt agcttgcaga tattcgacgt agaccacggg
    21601 cagtgcgcac tactgacgat gccaggagac agtggaacga tctatcgggt cctcatcgat
    21661 tgtgggcacg cggtgaactt ccagggcgcg ccgtggtatc cgggtgcaca cctgcaaagc
    21721 cttggtgtga gttacatcga catgctcgtg tgcacgaact tcgacgaaga ccacatgagc
    21781 ggctatcccg atctggtaag ccgtggcatc agcatcggct gcatcttggg caatccgacg
    21841 gtcgcacccg aaaccatcgc caagctcaag acccgagacg gcatgggcca aggtattgag
    21901 gcgctcgcca acacgctcgc aatccgcagg agcatcgcgt gggcgcagat acctccctcc
    21961 atcccaaacg tccacatgat ttggtcgtgg aatccctacc catactttga cgacgaaaac
    22021 aatctcagcc tcgtcttcac tctggacgtc caagggttcc ggttcatgtt cccaggcgac
    22081 atggaaggca acggatgggc caatctccta gcaacgtgcc cggcgttcag gccgctcgtt
    22141 tctggagtcc acgtcctggt agctgctcac cacgggcgtc ggaacgggat cttcgaggaa
    22201 atgttcgatg tatacggctg caccccgcag ctagtcgtca tcagtgacga ctacaagcag
    22261 tacgacacgc aagaaacgac caactactac agtcgcaagg caatcgggat caccaactat
    22321 cgcggtcaat caggcgtgag aagagtgctg acgacgcgaa gtgatggaga aatccggttc
    22381 tcgttcctca atggccagtg ccatgtctgg tagccggcca cgctgtattc ctcgcgtcta
    22441 accgaattag tgtggcgacg cgagagcgcc aattgcggat atccggaact catcgcagca
    22501 gcgctgatag cccacgagga tttcggcgca ccgccatcac agttcttcgc tcgggtcgga
    22561 aatgtccagc ttgaactgcc atccctcgaa cgtcatcagc atacggccga agtcttccca
    22621 ggagatttcc cggccatcga ccacgacaag tggcgtgcgc tcggcggcgg aatcatccca
    22681 ctcaatgcgc ccgtgcaccg tgcggtcggc gatttgcagt ccgtattcgc cgtccgtcag
    22741 gtgctgcgtg gacagcgccc gccgcatctt ttcaatcagg cgacccagca gcacgaacac
    22801 atcgtcgctg ggctgtccga ccacttggaa ccgatagccg gcgggacttc cgtcccggag
    22861 ttcgaaggca tccagtgcca caatattccc gagcaggcgc gtctggaaat ggaattcgtg
    22921 cttctcgcca gcacgatcca ccgtcccgat gggctcgaaa cggatgcttg cgaagttctc
    22981 atgaccggta tgcttggcca cctccgcgtt gaagcaacgg ctgcaaaggt c
//
LOCUS       DAOQPD010000060        22966 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1063_length_22966_cov_21.644101, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000060 DAOQPD010000000
VERSION     DAOQPD010000060.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 22966)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 22966)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22966
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1063_length_22966_cov_21.644101"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..447)
                     /locus_tag="PK063_13330"
     CDS             complement(<1..447)
                     /locus_tag="PK063_13330"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98080.1"
                     /translation="MQRHMWGVLLFVLSAIAGDASAAGVVVRIYPMTTVSCHLDSIQA
                     KFTAAKSTYRMTGRCDQQLKYEDHVEVIPIPWTSEGAYAPGQGKVAETIQLNGNPPLR
                     GKIETRLGCVEDPWLVMGKAACTQPVFSSTGDVQSLDYIVTYLRNGF"
     gene            complement(500..2137)
                     /gene="lnt"
                     /locus_tag="PK063_13335"
     CDS             complement(500..2137)
                     /gene="lnt"
                     /locus_tag="PK063_13335"
                     /inference="COORDINATES: protein motif:HMM:TIGR00546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016410 - N-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006497 - protein lipidation [Evidence
                     IEA];
                     GO_process: GO:0042158 - lipoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="apolipoprotein N-acyltransferase"
                     /protein_id="HMZ98081.1"
                     /translation="MTAHQRLRVTDGITPIALALLSAALLVVSLPSPDIGWLGWGALV
                     PILLAIQGLSPGRAAALGLLTGVLASFGMYGWLFEVPSFDLRHAVLLALYVGAYPAIW
                     ASATSWALRRDIPLLLCAPVLWLLIDYLRGHAGFLALPWGTLAQTQHRNLALLQTASM
                     IGEHGVTFLVALGNAALAALCLRRERTYATVALLILVTAHAWGATELFSPATGRSIRV
                     AALQPNIQIGDRTTEAGREANLARLERLTREAASERPDLIVWPESAIPGDVSDPALLH
                     RLQQLSSDTAVPLILGAAEVEKFATGDNLLTIGRRLFNTAHLFQPSGATSPPYRKRML
                     VPFAEYVPQADVIPWPEWLAPRVTELTAGDSGQLFTIAPQMSVAALICWENLFSHLAR
                     ESVNGGAQLLVQLTNDVWFGPTAAPRQHNLMSVMRAVENRVPVVIASNAGPSQLIDGY
                     GRVVAATSNVFQESAITGAVALGGGGTVYSKTGDWFVLFVLAGAFCTYVLLKRAHPGR
                     YANRPSFNWIRGVPGSLVVASMLGRGRRVLGRATPER"
     gene            complement(2265..2906)
                     /locus_tag="PK063_13340"
     CDS             complement(2265..2906)
                     /locus_tag="PK063_13340"
                     /inference="COORDINATES: protein motif:HMM:NF016648.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FecR family protein"
                     /protein_id="HMZ98082.1"
                     /translation="MTSSLLRSTVIMLGLLAGGVAPAWAANAPVGWAVNAIGTLTIIR
                     ADGVEEQLQGRKTLPLYEGDVLKTDASSQAYIQLKQGVNVALNEETSFKILSRWQKDK
                     PTTWILRLSQGEVWAKTAGDGPKAFEVETPVATAAVKETEFNLKVQPDGQSILTVIEG
                     VVQFGTAFGTCPIRTNTISYGVRGKKCTKPAESDAKAAKAWTTTLIPPSAPVQ"
     gene            complement(3002..3997)
                     /locus_tag="PK063_13345"
     CDS             complement(3002..3997)
                     /locus_tag="PK063_13345"
                     /inference="COORDINATES: protein motif:HMM:NF021778.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome D1 domain-containing protein"
                     /protein_id="HMZ98083.1"
                     /translation="MSSSWARIGAATLGLIGLAGCAEVETVKAPIDIPSRIYTANESS
                     NDVSVIDATSFAPVGNIDSKNQSTHDIAVSRDGRRVYATNLASGRLSVMDAGTMETIA
                     SIYTGQRCHVVALTNDNKQAWVANIGDNNISIVDTETFRIVGTIPTGKGPTGLTFSHD
                     GKFAYVSTQGDKTVDIIDTATHQIVKSLQVGANPHFLVVGPKGYIWGTNTGGTDIYVI
                     DPTTQEISGTLEVGAKPQQIAFGFKGMQGPNVFVTVGGTNKVAMVPADPKNLKVLEEF
                     AVGEGPNGIWANPEGTRIFVGHDKGNEVRIIDTGTGQNLGTVPVGRKPIRVVVSR"
     gene            complement(4065..7160)
                     /locus_tag="PK063_13350"
     CDS             complement(4065..7160)
                     /locus_tag="PK063_13350"
                     /inference="COORDINATES: protein motif:HMM:NF012862.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="caspase family protein"
                     /protein_id="HMZ98084.1"
                     /translation="MRVNLFVVTALLCLFTLLVPSTWASPSTTAPRLLSGHASEILTL
                     AFSPNGTVLATGGTDQTIRLWDPESGQDLKLLRGHMGAVHALAFSPNGKFLASGSADT
                     SVRMWDLASGRELHAVTSNFGAVRAVAFSADGKMLAAGGNDGSLRFLDSANGKELRSV
                     RGQFGIVFSIAFSPDGTMVATGSSDMQIHLWDLATSRQRTVLTGHTGAVHAVAFAPVS
                     HLLASASADGTIRLWDVDSGQERLTLNGHKGEVFGISFAADGRTLASVGADGSVRVWD
                     VVSGRERYALTSHKGPARTVALSPDGNVVASGGRDKTVRLQPSTPSTVTANTAEKIAQ
                     RGNETGAAPSPPPMPEADLSIQPMELKAGQPVTLTVTVTNRGKGPLYRFQARSKSDDP
                     ALNGLLFYMGKVDPGQSVADAVTLPLPPDRPDGTIPLSLEFEEYNGFTPAPLQAALAL
                     TGQPRPRFAFTHQLLDDGSGQSVGNSDGRIQTGEAIDILVTIKNVGPVLAQHTTIDLT
                     VPQSRDFRLSQSTLDFGPLKPEETKIARVNLFVARDTKADELPLRLFIRERGMNVTLD
                     GTLKLAIDHRPAPQIIATNKLVSVHDASAKIHSGAGEETSVIASAAKDQGLAVTGELG
                     DWWRVQISPKETGWIAKRDAREPVERVKGDMPIPSIAGAPVVKLFQNAPPVIALASPS
                     DGADVTVDRILLAGAAASERGIARVEIRVNGHLLTQREARGIAVAPDAPAAQPNLEFS
                     ERLTLKEGKNEIVVSAIDRDNLSAQKVITVIRQVDRAKVWAVVIGISKYKTVHPLRYA
                     DVDAQAFHDYLMRNVGVPPENATLLLNEQATLMNLKRTLGTELKRKAAEKDTVIIYYA
                     GHGAPEADASASDDDGLEKYIVPYDADPKDLYSTGLPMREVETIFNRLAPERVIFISD
                     SCYSGAAAGRTFATASRRAVVSDTFLSRLSKGKGRIVLSASKASEVSEEREDLGHGVF
                     TYYLLEGLRGNADTDRDGVITVDEAYGYVSKKVPEVTGQNQHPVKKGEVEGQLILGQV
                     R"
     gene            complement(7461..7757)
                     /locus_tag="PK063_13355"
     CDS             complement(7461..7757)
                     /locus_tag="PK063_13355"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98085.1"
                     /translation="MLSLILTLAFLILPYPLPVHVVLPATSAEAALLGGTIVSINQEA
                     LSLTILFPTGESRALSVRDARLLHGLSVGDHVTFELNDEHTLIKIAKLPTDPAN"
     gene            7892..9112
                     /locus_tag="PK063_13360"
     CDS             7892..9112
                     /locus_tag="PK063_13360"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006083 - acetate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HMZ98086.1"
                     /translation="MPPSKSDVPALLTVNAGSSSIKWALFHLGASPVRTASGRIERIG
                     IPDGIVTVTDRATGQDQRHIAQIPNHAAAVQILIDQLGQSGRGSSLQAIGHRVVHGGS
                     RYTNPEVISTAVMEELRRLSPYDPEHLPAELTIIDALRAQYPTVPQVACFDTGFHQHL
                     PAVARLLAIPRRYEKQGVRRYGFHGLSYAYLMEELERVAGHEAAQGKVVLAHLGNGAS
                     LAAVRDGVSIDTTMGFTPASGLPMSTRSGDLDPGLVSYLSQTEGMTAEQFHHMVHAQS
                     GLLGLSELSPDLRDLLAQERHDTRAAEAVGVFCYQGKKWIGAYAAALGGLDQLVFSGG
                     IGEHSSVVRARMCDGLAFLGIQLDQARNDAHEAVISAPGSRVTVRVIHTDEERHIAQS
                     VCRLLDLPLSGGTK"
     gene            9176..11551
                     /locus_tag="PK063_13365"
     CDS             9176..11551
                     /locus_tag="PK063_13365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
                     /protein_id="HMZ98087.1"
                     /translation="MTQTTHTNQPLSAEMVQRIHAYWRAANYLSVGQIYLYDNPLLKQ
                     PLKREHIKPRLLGHWGTTPGLNFIYAHLNRIIKAQNLPVLYIAGPGHGGPGLVANVYL
                     EGTYSEVYPNISQDEAGLQRLFKQFSFPGGIPSHVAPETPGSIHEGGELGYSLAHAYG
                     AAFDHPELLVACVIGDGEAETGPLAGSWHANKFLNPVRDGAVLPILHLNGYKIAGPTV
                     LARMPPDELESLLIGYGHQPFFVEGDDPETMHQLMASTLDEIVATIRRIQQEARSHGF
                     TRRPRWPMIVLRTPKGWTGPKEVDGKLTEGTFRSHQVPMAEMDKPGHVELLERWLKSY
                     KPEELFDDTGKLMPELASLAPTGERRMGAIACANGGIILRDLHMPDFRQYAVPVVKPG
                     AEEAEATRVQGLFLRDVLKLNMRNFRIFGPDETASNRWGAVFEVTDRCSTEEILPTDE
                     HVSHDGRVMEILSEHLCQGWLEGYLLTGRHGFMNCYEAFIHIVDSMFNQHAKWLKTSR
                     EIPWRRPIASLNYLLTSHVWRQDHNGFSHQDPGFIDHVVNKKAEVIRVYLPPDANTLL
                     SVTDHCLRSRDYVNVVVAGKQPAPQWLDMESAILHCTAGIGIWEWASNDRGSDPDVVM
                     ACCGDVPTMETLAAVEILRVAQPNLKVRVVNVVDLMKLQPASEHPHGMSDKEFDALFT
                     TDKPIIFAFHGYPWLIHRLTYRRTNHHNLHVRGYKEEGTTTTPFDMVVLNDLDRFHLV
                     ADVVDRVPQLGARAAYLKQEMRDKRMQHKQYIEIHGTDMPEIRNWKWSGKR"
     gene            11555..12241
                     /locus_tag="PK063_13370"
     CDS             11555..12241
                     /locus_tag="PK063_13370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HMZ98088.1"
                     /translation="MAVPRVVALFDVDNTLMDNDRITADLTQHLDEEIGARGERQYWA
                     IFEELREKLGYVDYLGALQRYRQEYPRDPHLLALSRFLLNYPFTERVFPQVHEVIRQT
                     AQWAKPVILSDGDVVFQPHKVDRSGLFDAVQGHVLIYIHKEQELDDVEQRYPADHYVL
                     IDDKLRILTAVKARWGARVTTVFPRQGHYAKDPEVLRTYPAADLSIDRIGDLLTLDRS
                     ALLAAAKPRT"
     gene            12296..13357
                     /locus_tag="PK063_13375"
     CDS             12296..13357
                     /locus_tag="PK063_13375"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HMZ98089.1"
                     /translation="MTPKTPVNRIWSLMLGRRQLLKGLGVAGSFMALGGPGRLAEALA
                     ADSPATGTSSGDIPRRALGKTGVQVSALCFGGAHWGRIQDDGEAIRLLHAAIDAGVNF
                     FDNAWEYNGGRSEELMGKALQGKRQQVVLMTKVCSHGRDKKVALQQLDESLRRLKTDY
                     LDLWQIHEVVYEDDPDRHFAPNGATEALLEAKRQGKVRFIGFTGHKHPDIHLKMLSHD
                     FPFDTCQMPLNVFDGTYRSFEREVLPVLNQRGIAPLGMKSLTGNAEPIKQGIVQPEEA
                     IRYVLSLPIASLVSGIDSPQVLKQNLDIARRFTPMTIAEMEGLRARVAMFAMDGRYEL
                     FKSTNRYDGPIGRQQHGIS"
     gene            complement(13444..15030)
                     /locus_tag="PK063_13380"
     CDS             complement(13444..15030)
                     /locus_tag="PK063_13380"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98090.1"
                     /translation="MAHSFSDEQILQQSIRRRWGAIDWDLHFPWWRRPAKVRILMYAD
                     GSVHFNGGSFLGLQYVYNLLKTRAYSYVDFAIDFAHRTGGDPSATIAGARQLTDPALD
                     IMNKYDEIWFFGIESTPNLTAAEVALLTQFMAGPKFGGVLVTGDHDNLGRGISGQIPR
                     AGVMRRYPAPPDYGPTWNTTLEDGPDAGSTFDFDDQSDDTPQSIRWKRYTIASPLLLT
                     RRYRPHPVLCGPDGPINFLPDHQHEGEALAPTPVSGDPAWPTKGGHQETPEVIAWGRI
                     KDPNATKHGQEIGVISAYNGHNVDVGRILADSTWHHWFDINLTGRFAPPSPYSGFDET
                     PAGQLALKKIDAYFLNCGVWLAPPARQIEMRNAAWWSILWTDRMVELSPAASLTRFGE
                     EAIDALGGRASRCTVSEFIFKEPIFKEKIPRHEWPMLFDRFQLIDLPFERYVAGGILR
                     QLLHEVGPHNPKLTFPGKPAADEVLDKAIRTGTEEGLMALSKDLRREARMAVRLADSG
                     FLASALEDRVQRVTEETVTA"
     gene            complement(15432..16865)
                     /locus_tag="PK063_13385"
     CDS             complement(15432..16865)
                     /locus_tag="PK063_13385"
                     /inference="COORDINATES: protein motif:HMM:NF024484.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3943 domain-containing protein"
                     /protein_id="HMZ98091.1"
                     /translation="MSLSQDQPLTPAADNGQRNLVGPVNHADRTESPSNPSGRSSALN
                     WETREGRSYLIPAAEILAYLFLLNQFDRHFTEPMSDYRTTGSTIRQHLTDSKWVLDND
                     QFSVNQFLHPYSGSIYFGLARSSGLNFWESSLYSVAGSFLWEIGGEKTNPSINDMIAT
                     PIGGTFLGEPLFRMANLLLESDDGRPGFWRELGAAIISPPTGFNRLVFGNRFDAVYPS
                     NRPATFIRLAGGGTLTSSSHNVASNVNEHGAVGEFTLTYGLPGKPGYSYARPFDYFDF
                     HVSAATANTLETITSRGLLAGKTYASGDTTRGIWGLFGSYDYISPQVFRVSSTALSLG
                     TVWQSWLADELALQGTFLGGAGYGAAGSIQRTEERDYHYGTTPQALLALRLIYANRAM
                     LDITGREYYVSDFLSPERHGQENIVRAESSLTLRVFDRHGVALRYSLSHRDAHYPSVE
                     FRNQTVTAVSLMYVILGDSGFGAVEWR"
     gene            complement(17053..17952)
                     /locus_tag="PK063_13390"
     CDS             complement(17053..17952)
                     /locus_tag="PK063_13390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HMZ98092.1"
                     /translation="MAPRVTHRAGTYSPHRRRSRRRLTFTSLWRFTGRRWRDLRAFLR
                     AWGNTHPLPRLLIGIILIACLWGTLNWTYHAINKPTEVLFPLEDALDKNPAATWQEYG
                     PLFREHSTAIITPDLLAALAQVEGSGNPVARTYWRWRLSWNPFDWYRPASSAVGMFQL
                     TDGTFREAKRYCIHNHVVVEDGPWNDMHACWFNSFYTRIVPSHAIELTAALLDRQVAA
                     AIGSRRSASISRQQKQDLAAVIHLCGAGAGHAFVARGFHLAPHQKCGDHHASSYLARV
                     NGLKVQFARLAAGSSLQRLIKPR"
     gene            complement(18065..18847)
                     /locus_tag="PK063_13395"
     CDS             complement(18065..18847)
                     /locus_tag="PK063_13395"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98093.1"
                     /translation="MIRVDITGEVEPQDVIQAIAALRENDQARQELLALRAETDRLQA
                     QVDDTNRALAAASTPYDVQQYTDQRQDMLDQLQANALLSQAWTSWTYPTLGFYSYPWI
                     GVSGINGLLLQAQRLSPHHRHLPLAQRTIMANLSAPPASPPVSTAPRASLLVPPVPHV
                     HHQQAAPLLNSQGQQAKVGDVVVIPTPRSIPSTPQYTPHAPPYQVHPNHFWRPTPPNV
                     QSLSSVPPQHSPSVSMAPRSSGGYAGHSGGGHSHSGGGHHGR"
     gene            complement(18851..19351)
                     /locus_tag="PK063_13400"
     CDS             complement(18851..19351)
                     /locus_tag="PK063_13400"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98094.1"
                     /translation="MFFSRSTPTTAALLVLWLSVLPTAPSFASTTIYSYTNDEGVQTF
                     TNELASVPEKYRPQLTQRSFDTPARPETPAPDMASELRPRSAEARTITARGEYRMGDH
                     DNRADAVRLATEAAKQDALEQVATYVERITEVKDLNVTRDDIRSFTAGVVRVIDQTVT
                     TRLEQD"
     gene            19554..20222
                     /locus_tag="PK063_13405"
     CDS             19554..20222
                     /locus_tag="PK063_13405"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98095.1"
                     /translation="MLVVKRIIAVVFGLVPLVLIAAGVAMVFRELRPTDPLLYSVQQD
                     GELPEAFMFAAVGCAGLFGCHRLWRADAGWKWTLMPIAVMVAAIAIPNLLYGHHGSPS
                     DRAYSNMFLRLGTFAVSSKQLAQEQGQFTCDPSVKLFGLSRFTQNGQPLPYVIHCVLD
                     ATGLALATPPERPGTLVFAVSPDRKQAWFAATVLARRTDRHATWLRQQGQPRVIAFSV
                     QEKN"
     gene            20376..21707
                     /locus_tag="PK063_13410"
     CDS             20376..21707
                     /locus_tag="PK063_13410"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024760.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family glutamic-type intramembrane
                     protease"
                     /protein_id="HMZ98096.1"
                     /translation="MSQPSPSVPSNLFLLCISGPDLGKRIALRDGELLIGRSLQCDVL
                     SDDQDVVERHAVVLWENGQLICRAVQGIVYLDGHKTMESVLTPQQQIRMGRSLWQLNG
                     PTPGRGSGGWIEDLSDRISEVAGVERLQGFNARDMFSDVLRKRTDEEIEEHFTAGTLT
                     TTPPIEKVITGWPKPWVFFKTFILSAVVYLAFVFAMKEFNNANLVPGLIMTGAFLIPS
                     SLLIFFFEMNVLRNVSLYQVVKMVMFGGVTSLILSLFLFKWTDLDSWMGAMSAGVIEE
                     TGKALALLLIINNQKYRTALNGLLFGAAVGTGFSAFESAGYALMAGLSGGQSAMLHSI
                     TVRGLLSMLGLHIVWTSMVGAALWRIRGNRSFTIEMLYDKRFLRIFGLAVALHMFWNA
                     PFNLPFYLKYIALGFIAWVVNLALVQVGLREVKALQEAQASEASDSRLRTA"
     gene            complement(21739..22398)
                     /locus_tag="PK063_13415"
     CDS             complement(21739..22398)
                     /locus_tag="PK063_13415"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98097.1"
                     /translation="MKHHTEPDGTLVVTIDSRFIVGMLTGAALLCAVPVFRSWLIGGA
                     TAHDATPLIGSAMFLVGAFFSYERNRFVFDPHLKEVRWSRRSLMAKDEGRMPFSCLRS
                     LTVQAAIGSTKTAPLVRLALVTDEREIPLSRAYAGGMRREYEELAITIRRLMQMNAER
                     TNFLLDSLTAALAQGRKLDAIKLVRMTKDMTLEEARQFVEQLAVSPTAGSRSNDSPPS
                     S"
     gene            22465..22929
                     /locus_tag="PK063_13420"
     CDS             22465..22929
                     /locus_tag="PK063_13420"
                     /inference="COORDINATES: protein motif:HMM:NF012514.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HMZ98098.1"
                     /translation="MPKKLSAGIVLYRRIGGGLQVFLVHPGGPFWAKKDSGAWSIPKG
                     EYIEGEEPETVARREFQEETGGELTGRLQALTPLKQPSGKVISAWAVEGDIDPAELKS
                     NSFYLEWPPRSGTIQQFPEVDRGAWFDLPTAQEKMLVGQRPFLEELVRFVKE"
BASE COUNT         4525 a         6443 c         7147 g         4851 t
ORIGIN      
        1 gaagccgttc cgcaggtagg tgacgatgta atcgagactt tgcacatctc cggtggaaga
       61 aaagaccggc tgggtgcagg ccgctttgcc catcaccagc cagggatctt ccacgcaccc
      121 aagcctggtt tcgattttcc cccgaagcgg cgggttcccg tttaattgga tcgtttctgc
      181 caccttgcct tgcccggggg cataggcacc ttccgaagtc catggaatcg ggatcacttc
      241 cacatggtcc tcgtacttca gttgctgatc gcaccgtccg gtcatgcgat aggtggattt
      301 cgccgccgtg aactttgctt gaatggagtc cagatggcag ctgaccgtcg tcatcggata
      361 gatcctcacg acgacgccag cagcactggc atcaccggca atggcggaca gcacgaacaa
      421 cagtacgccc cacatgtgtc tctgcatgaa gatccttcct tatcctgatt caaatgatgg
      481 cgcgtgatct ttcttatggt catctctccg gagtcgcccg tcccagtacg cgccggcctc
      541 gtccaagcat ggaagcaacc accaaggatc cggggacccc cctgatccaa ttgaacgagg
      601 gccggttcgc gtatctaccc gggtgtgctc gcttcaagag aacatacgtg cagaatgcac
      661 cggcgagcac gaacagaacg aaccaatccc cggtcttcga gtagacggtg cctcctccgc
      721 cgagggccac agcgcccgtg atggccgatt cctgaaagac gttcgatgtg gcggcgacca
      781 cccggccata cccatcgatg agttgcgatg gacctgcgtt cgaggcgatc acgaccggca
      841 cacgattttc cacggctcgc atgacggaca tgagattgtg ttgccggggg gcagcggtgg
      901 ggccgaacca gacgtcgttc gtcagttgaa ccagaagctg tgccccgccg ttgacggatt
      961 cccgggcgag gtgtgagaag agattttccc aacagatcaa tgcggcgacg gacatctgcg
     1021 gcgcgatcgt aaacagctga ccactgtcac cagcagtcag ttcggtgacg cgcggagcaa
     1081 gccattcggg ccagggaatg acatcggcct gcggcacata ttcggcaaag ggcacgagca
     1141 tgcgtttgcg atagggaggc gaggtcgcgc cactcggctg gaatagatga gcggtgttga
     1201 acagccgtcg tccgatggtg agcagattgt cacccgtggc gaatttttcc acctcggctg
     1261 ccccgaggat caagggcacg gcggtgtcgc tgctcaactg ctggaggcga tgcagtaaag
     1321 ccgggtcgga cacatcgccg gggatggcgc tttccggcca gacgatcaaa tccggtcgct
     1381 ccgaagccgc ctctcgcgtc aaccgctcaa gacgggccag gttggcctcc cgacctgctt
     1441 ctgtcgtgcg gtcgccgatt tgaatgttgg gttgaagagc cgcgaccctg atggatcgtc
     1501 ctgtggcggg cgagaagagt tcggtggcgc cccaggcgtg tgccgtgaca aggatgagga
     1561 gcgcgactgt cgcgtatgtt cgctctcgtc tcaagcacag ggcggcaagg gcggcattgc
     1621 ccagtgccac caggaacgtg acgccatgtt ctccaatcat gctggctgtc tgcagcagcg
     1681 cgagattacg atgctgcgtc tgagcgagcg tgccccaggg gagcgctaaa aacccggcat
     1741 gtccacggag ataatcgatg agtagccaga ggaccggcgc gcacaggaga agcggaatgt
     1801 ctcggcgaag tgcccaggaa gtggccgatg cccatattgc cggataggct ccgacgtaca
     1861 gagctagcag cacggcatga cgtagatcga agctaggcac ttcgaacagc cagccataca
     1921 tgccgaagct agccaggacg ccggtcagca gtcctagcgc ggccgcccga ccagggctga
     1981 gtccctggat ggccaggaga atcgggacga gtgcgcccca acccaaccag ccgatatcgg
     2041 gggagggcag ggatacgacg agtagtgccg cagatagcag cgccagcgcg ataggtgtga
     2101 tgccgtcagt tacgcgcagc cgttgatgtg ccgtcatccc gactccccct gtcggcctca
     2161 ggcgctccat tcagatagcg actattcccc ataccgtcgg accggctctg atcgactcaa
     2221 ccgcccgagg taagtctgcc gatcgtcggc acaggttcat tctattattg caccggcgcc
     2281 gacggcggaa tgagcgtggt ggtccaggcc ttcgccgcct tcgcatcgct ctccgcgggc
     2341 ttcgtgcatt tcttgccgcg cacgccgtaa ctgatcgtgt tggtccggat cggacaggtt
     2401 ccgaaggcgg tgccgaattg gacgacgcct tcgatcaccg tcagaatgct ttgcccgtcc
     2461 ggctgcactt tcaaattgaa ttccgtctct ttgacggctg cggtggccac gggggtttcg
     2521 acctcgaagg ccttcgggcc atcaccggcg gtcttggccc acacttcgcc ttgactaagc
     2581 cggaggatcc atgtggtcgg tttgtccttt tgccagcggg agagaatctt gaacgaggtc
     2641 tcctcgttca gcgccacgtt gacgccttgt ttcagttgaa tgtaggcctg gctggaagcg
     2701 tccgtcttga ggacgtcacc ttcatagagc ggcagggtct tccggccttg gagctgttcc
     2761 tctacgccgt cggcgcggat gatggtcaag gtgccgatag cattgaccgc ccatcctacc
     2821 ggagcattgg cggcccatgc gggtgccact ccaccagcaa gtaatcccaa catgatgacc
     2881 gtagatctga gtaatgatga cgtcataaat tcctcttcgc gtcttgtcgc cgcgcgttat
     2941 gtcagttcag tgtgtcgaac gcccgcatcc ccaagatgcg cgcggtacat gcgtccggcc
     3001 gctatctcga gaccacgact cgaatcggct tgcggccgac cggcaccgtg ccgagatttt
     3061 gtcccgtgcc cgtgtcgatg atgcgcactt cgttaccctt gtcgtgaccg acgaagatgc
     3121 gggtgccctc cgggtttgcc cagatgccgt tcggcccttc acccacggcg aattcctcca
     3181 ggaccttcag gttcttggga tctgccggca ccatcgccac cttgttggtc ccgccgacgg
     3241 tgacaaacac attaggcccc tgcatgcctt tgaacccgaa cgcgatctgc tgcggcttcg
     3301 caccgacctc caatgtgccg gagatttcct gcgtggtcgg atcgatcacg tagatgtccg
     3361 ttccaccggt attggtcccc cagatgtacc ccttggggcc gaccacgagg aagtgaggat
     3421 tggcgcctac ctgcagagat ttcacgattt ggtgcgtggc ggtatcgatg atgtcgacgg
     3481 tcttgtcgcc ctgggtgctg acgtaggcga atttgccgtc gtgcgaaaaa gtcaggccgg
     3541 tcggtccctt gccggtgggg atggtgccca caatcctgaa ggtctccgta tccacgatcg
     3601 aaatattgtt gtcgccgatg ttggcgaccc acgcctgttt attgtcgttg gtgagtgcca
     3661 ccacatgaca gcgttgcccg gtataaatgg atgcgatggt ttccatcgtg cctgcgtcca
     3721 ttactgagag ccggccgctg gcgaggttcg tggcatagac gcgccggcca tcgcgcgaga
     3781 cggcgatgtc atgcgtggat tggttttttg aatcgatgtt gccgaccggc gcaaagctcg
     3841 tcgcgtcaat gaccgagacg tcgttcgagc tttcattggc ggtataaatg cgcgatggaa
     3901 tatcgatcgg cgccttgacg gtttcgactt cggcgcaacc ggccagaccg atgagcccaa
     3961 gcgtggccgc gccgatgcgt gcccatgacg atgacataac aatcctcctt actgatctat
     4021 gaacatgaca gaatgataaa gtgccctata taagcgacga tgtgctaccg cacctgtccc
     4081 aggatcaatt gcccttccac ttcacccttc ttcacgggat gctgattctg ccccgtgacc
     4141 tccggcacct tcttggagac gtagccgtag gcttcatcga cggtaatgac gccgtcgcga
     4201 tcggtgtccg cgttgccgcg caggccttcg agcaaatagt acgtgaacac gccgtgtccc
     4261 aggtcttcgc gctcctcgct gacttcgctg gccttgctcg cactgaggac gatacgccct
     4321 ttcccctttg aaagccggct caggaatgtg tcggagacca cggcgcggcg cgaggcggtg
     4381 gcgaaggtgc ggcccgccgc ggcgccgctg tagcaggaat cgctgataaa aatcacgcgc
     4441 tcgggcgcaa gccggttgaa aatcgtctcg acttcccgca tcggcaggcc ggtcgagtag
     4501 aggtccttcg ggtccgcatc gtagggcacg atgtattttt cgaggccgtc gtcgtccgag
     4561 gcagacgcat ccgcttccgg cgcgccatga ccggcgtaat aaatgatgac cgtgtccttc
     4621 tccgccgctt tacgcttcag ttccgttccg agtgtgcgtt tcaaattcat caacgtcgcc
     4681 tgttcgttca acagtagcgt ggcgttctcc ggcggaacgc cgacattgcg catcaaatag
     4741 tcatggaagg cctgcgcatc cacatccgca taccggagcg gatggaccgt cttatatttc
     4801 gagatgccga tcaccacggc ccagaccttg gcacggtcca cctgccggat aacggtgatg
     4861 accttctgtg ccgaaagatt gtcgcggtcg atggcggaca cgacgatttc gtttttgccc
     4921 tccttcagcg tcaggcgttc cgaaaattcg aggttcggtt gtgccgccgg cgcatccggc
     4981 gcgacggcaa tccctctcgc ctcacgctgg gtcaggaggt ggccgttgac gcgaatctcc
     5041 acccgcgcga tgcctcgttc actggccgcg gccccggcaa gcagaatccg gtccaccgtt
     5101 acgtctgctc catccgaggg ggaggcgagt gcgatgaccg gaggggcgtt ctggaacaat
     5161 ttcacgaccg gcgcaccggc aatcgaagga atcggcatgt cgcctttcac acgctcgaca
     5221 ggttcacgcg cgtcgcgttt ggcgatccat ccggtttctt tgggggagat ctgcacgcgc
     5281 caccagtcgc cgagttcgcc ggtcacggcc aggccttgat ccttggcggc ggacgcgatg
     5341 accgaagttt cttcgccggc gccgctgtga attttggccg aggcgtcatg caccgagacg
     5401 agtttgttgg tcgcgatgat ttgcggcgcg ggccggtgat cgatggcgag cttcagtgtg
     5461 ccatccagcg tgacgttcat gccgcgctcg cgaatgaaga gtcgcagggg gagttcatcg
     5521 gccttcgtgt cgcgcgcgac aaacagattc acgcgggcaa ttttggtttc ctctggcttc
     5581 aaaggcccga agtcgagtgt gctctggctc aggcggaagt cacgtgactg gggcaccgtg
     5641 agatcgatcg ttgtgtgctg agccaggacg gggccgacgt tcttgatcgt gaccagtatg
     5701 tcgatggcct cgccggtctg gatgcggcca tcgctgttcc cgaccgattg gcctgatccg
     5761 tcatccagca attggtgggt gaaggcaaac cgtggtcggg gttgtcccgt gagggccagc
     5821 gctgcctgca gcggggcagg cgtgaagccg ttgtattctt cgaattcaag cgagagggga
     5881 atggtgccgt ccggccggtc gggcggaagg ggcagcgtga cggcatcggc cacggactgt
     5941 cctggatcga ccttccccat ataaaacagc aggccgttca atgccggatc gtcgcttttg
     6001 cttctggcct ggaagcggta cagagggcct ttgcccctgt tggtgacggt cacggtcagg
     6061 gtgaccggtt ggcccgcttt taattccatc ggctgaatgg agaggtctgc ttccggcatg
     6121 ggtggtggag agggggcggc gccggtttcg ttgccgcgtt gtgcgatctt ctccgccgta
     6181 tttgccgtga cggttgaagg agtgctgggc tgcagtcgca cggttttatc tcgcccgcca
     6241 ctcgccacca cgttgccgtc gggagacagg gccaccgtcc tcgccggtcc tttgtggctt
     6301 gtgagggcgt agcgctcgcg gcctgagacc acatcccaca cccggacgct accatcggct
     6361 ccgacggagg cgagcgtgcg gccatcggcc gcgaaggaga tgccgaagac ctcgccctta
     6421 tggccgttca gggtcaagcg ttcctggccg ctgtcgacat cccagagacg gatcgtgccg
     6481 tcggcggaag cgctggcgag gaggtggctg accggagcga aggccacggc gtgcacggcg
     6541 ccagtatggc cggtgagcac cgttcgctgc cggctggtgg ccagatccca gaggtggatc
     6601 tgcatatcgc tactgcccgt cgccaccatg gtgccgtccg gggagaaggc aatgctgaag
     6661 acaatcccga actgcccccg caccgatcga agttcttttc cgtttgcact gtctaaaaac
     6721 cggaggctgc cgtcattgcc gcctgcggcc agcatcttgc cgtcggcgga aaaggcaacg
     6781 gcgcggactg cgccgaaatt cgaggtcacg gcgtgcagtt cacggcctga tgcgaggtcc
     6841 cacatgcgca ctgaggtatc tgcgcttccc gaggccagaa attttccgtt cggagagaag
     6901 gccagggcat ggacggcgcc catgtgaccg cgcagcagct tcagatcctg tccactctcg
     6961 ggatcccaga gacgaatggt ttgatcggtc ccgccggtgg caaggacggt tccattgggt
     7021 gaaaacgcca gggtcaggat ctcactggcg tgaccgctga gcaggcgtgg cgctgtggtg
     7081 gaggggctgg cccatgtgga gggtaccagg agcgtgaaga ggcacaggag cgccgtgaca
     7141 acgaacaggt tcacgcgcat gggggctatc cttttccgac ggaggtgccg gcctgtctca
     7201 ccgttcggat cagatgtctc acaaaaacca gtcttccgct tgtcctgttc ctgtctgtcg
     7261 ggtttccctg cctggaggtt cacccgtttt gcggcggcac cagtgtattt ttcggcattc
     7321 ccgattgtca atccacaggc gcgggcagcc ggtcaaatac aggtattggc aggtatacgc
     7381 ttgctgtacg gtcttgattc agtgctcaag agtggagact cgtagagggc acgtaagttc
     7441 aatgtggagg agggcgacaa tcagttggcc ggatcagtcg gcagcttggc gatcttgatc
     7501 aaggtgtgtt catcattgag ttcgaaggtg acatggtccc cgacgctgag gccatgcaga
     7561 aggcgggcat cccgaacgga aagtgcgcga gactctccgg tggggaaaag aatggtcagg
     7621 ctgagcgctt cctgattgat cgagacaatc gtgccgccca gcagagcggc ctctgcagat
     7681 gtggctggga ggacgacatg caccggcagg ggatagggga ggattagaaa agcgagggtg
     7741 aggatgagcg aaagcatccg acacgatagc gcagctcgtg cctgtgtgga actagcgttt
     7801 cccctatagc gacagtgcgc agaagaccta cagcaagagc cggggatttt ccggttgcgc
     7861 tgatcgtatg gtcgatctat ggtgggagga catgccgcca tccaaatcag atgtcccagc
     7921 cctgctgacc gtcaacgccg ggtcgtccag catcaaatgg gcgttgttcc acctgggagc
     7981 gtcgcctgtc cggacggcct ctgggcgaat cgagcgcatc gggatacctg acggcatcgt
     8041 gacggtgact gatagagcaa ccggccagga tcagcgccat atcgcacaga ttccgaacca
     8101 cgcggctgcc gttcagatcc tcatcgatca actcgggcag agcggccggg gatcgtcgct
     8161 acaggccatc ggccatcgag tcgtgcatgg aggaagccgt tatacgaatc cggaagtgat
     8221 ctcgacggcg gtcatggaag aattgcgtcg gctcagcccc tacgatcctg aacatcttcc
     8281 ggcggaactc accatcatcg acgcgctgcg cgctcaatat ccgaccgtcc ctcaagtggc
     8341 ttgtttcgat acgggctttc atcagcattt gccggcggtc gcgcggctgc tggcgattcc
     8401 tcgacggtac gaaaaacagg gcgtccgtcg atacggcttt cacgggttgt cctatgccta
     8461 cctcatggag gaattggagc gggtggccgg ccatgaggcc gcgcagggca aagtggtcct
     8521 ggcccacttg ggaaacgggg ccagcctcgc cgctgtgcgt gatggcgtga gcatcgatac
     8581 gacgatggga ttcactccgg cctcggggtt gccgatgagc accaggtccg gcgatctgga
     8641 cccgggtctg gtgtcctacc tctctcagac cgaggggatg acggcggagc agtttcatca
     8701 catggtacac gcgcagtcgg ggctgttggg attgtctgag ctcagtcccg acttacggga
     8761 tttgctggcg caggaacgcc acgatacgcg cgccgctgag gctgtagggg tattttgtta
     8821 tcaggggaaa aagtggatcg gcgcctacgc ggcggcgctt ggtggattgg accagctcgt
     8881 cttcagcgga ggcatcggcg aacattcatc cgtcgtgcgg gcgcgcatgt gtgacggcct
     8941 ggcatttctc ggcattcagt tggaccaggc caggaacgac gcccatgaag ccgtcatctc
     9001 tgcgcctggt agccgggtca ccgtgcgggt gatccatacg gatgaagaac gccacattgc
     9061 acaatcggtc tgccggctgt tggacttgcc cctcagtggc gggacgaaat gaaccgggcg
     9121 tcagacggat aggcacgagg cgaccgggta tgctcacatc tgaaagagga acttcatgac
     9181 acagacgacg cacacgaatc agccgctgag cgccgaaatg gttcaacgga tccatgccta
     9241 ctggcgcgcg gcgaactatc tctccgtcgg gcagatttac ttatacgaca acccgctgct
     9301 caagcagccg ttgaagcggg aacatatcaa gccgcgcctg ctcggccatt gggggaccac
     9361 gccggggctg aatttcattt atgcccatct taatcgcatc atcaaggcgc agaatcttcc
     9421 ggtgctctac attgccgggc caggtcatgg tggtccgggg ctggtcgcca atgtctatct
     9481 tgagggcacc tacagcgagg tctatcccaa catctcgcaa gacgaggcgg ggctccagcg
     9541 gctgttcaaa cagttttcat tccccggcgg cattccgagc catgtcgcac cggaaacgcc
     9601 cggctccatt cacgagggtg gcgagttggg atattccctg gcccatgcct atggcgcggc
     9661 cttcgatcat cctgaactgc tggtggcatg cgtcatcggc gacggggaag cagaaaccgg
     9721 gccgctggcg ggcagttggc atgccaataa gtttctgaac cccgtgcggg acggagccgt
     9781 cctgccgatt ctgcatctga acggctacaa aatcgccggc cccaccgtgc tcgcccgcat
     9841 gccgccggat gaactcgaat ccctgctgat cggctatggc catcagccgt tttttgtcga
     9901 gggtgatgat ccggagacaa tgcatcaatt gatggcctca acgctcgatg aaatcgtggc
     9961 gactatccgg cgcattcagc aggaggcacg atcccatggt tttacccgtc ggccgcgctg
    10021 gcccatgatt gtgttacgca ccccgaaggg atggaccggc cccaaagagg ttgatggcaa
    10081 gttgacggaa gggaccttcc gttcgcacca ggtgccgatg gccgagatgg ataagccggg
    10141 gcatgtcgag ttgttggagc gctggctgaa gagttacaaa cccgaagaac tgttcgacga
    10201 cacaggaaag ctgatgccgg agctggcttc gctggcgccg accggtgagc gacgcatggg
    10261 cgccatcgcc tgtgcaaatg gcggcatcat cctgcgcgat ctgcacatgc ccgactttcg
    10321 gcaatacgcc gtgcccgtgg tcaagcctgg tgcggaggag gccgaagcca ccagggtgca
    10381 gggactgttt cttcgcgacg tgttgaaact gaacatgcgc aacttccgga tcttcgggcc
    10441 ggacgagacg gcctcgaacc gctggggcgc cgtgttcgaa gtgaccgacc ggtgctcgac
    10501 ggaagagatt ctccccactg acgaacatgt gtcccacgat ggacgtgtga tggagatttt
    10561 gagcgagcac ctctgccagg gctggctcga gggctatctg ttgaccggcc gccacggctt
    10621 tatgaattgc tacgaagcgt tcattcacat cgttgattcc atgttcaacc agcatgccaa
    10681 atggttgaag acctcgcgcg agattccctg gcggcggccg atcgcctcgc tcaactatct
    10741 gttgacgtcc catgtctggc ggcaggacca caatgggttc agccaccagg atccgggatt
    10801 tatcgaccat gtcgtgaata agaaggcgga ggtgattcgt gtctacctgc cgccggatgc
    10861 caacactctg ctgtcggtca ccgatcactg cctgcgcagc cgtgactatg tgaacgttgt
    10921 cgtggcggga aaacagccgg cgccgcaatg gttggacatg gagtccgcca tcctccattg
    10981 cacggccggc atcggcattt gggaatgggc cagcaatgac cgggggagcg acccggatgt
    11041 cgtgatggcc tgttgcggcg atgtgccgac catggagacg ctggcggccg tggagattct
    11101 gcgtgtcgcc cagcccaacc tgaaggtgcg tgtggtcaac gtggtcgatc tgatgaagct
    11161 gcagcccgcc agcgaacatc cgcacggaat gtccgacaaa gagttcgatg cgctcttcac
    11221 caccgataag ccgatcatct tcgctttcca tgggtatccc tggttgatcc accggcttac
    11281 ctaccggcgg acgaaccatc acaacctgca tgtgcgaggc tacaaagaag aaggcacgac
    11341 gacgacgccg ttcgatatgg tggtgttgaa tgatctcgac cggttccatc tcgtagccga
    11401 cgttgtcgac cgtgtgccgc aactcggggc gcgggctgcc tatctcaagc aggagatgcg
    11461 ggataagcgc atgcagcaca agcagtacat cgagatccat ggcaccgaca tgcctgagat
    11521 caggaactgg aagtggagcg gaaagcgcta agttatggca gtacctaggg tggtggcgtt
    11581 gttcgatgtc gataatacgt taatggacaa cgaccggatt acggccgacc ttacgcaaca
    11641 cctggatgaa gaaatcggcg cgagggggga gcgccagtat tgggccatct tcgaagaatt
    11701 gcgggaaaag ctcggatacg tggattacct gggcgcgctg cagcgctatc ggcaggagta
    11761 tccccgcgat ccccatctgt tggccctgtc ccggttcctg ctgaattacc ccttcacgga
    11821 gcgcgtgttt cctcaggtgc atgaggtgat tcgccagacg gctcagtggg cgaaacccgt
    11881 gattctttcc gatggcgacg tggtgtttca gccgcacaag gtcgaccgct ccggtctctt
    11941 tgacgcggtc cagggccatg tcctcatcta catccacaag gagcaggagc tggacgacgt
    12001 cgagcagcgg tatccggccg accactatgt cttgattgac gacaagttgc gcattcttac
    12061 ggcggtgaaa gcccgttggg gcgcgcgcgt gacgaccgtg ttcccgcggc agggacatta
    12121 tgcgaaggac ccggaggtgc tgcgaacata cccggcggcc gacctcagca tcgatcgcat
    12181 cggcgacttg ctcacgctcg atcggagcgc gcttctggcc gccgcgaagc cacgtacatg
    12241 acgagcagtc ggaaggttgt gtgcctatca tccacctcta gcaggcaggt gattcatgac
    12301 acccaagaca cccgtgaaca gaatctggtc cctgatgctc ggccgccgtc aacttttgaa
    12361 aggactgggc gtggccggct ccttcatggc gttaggaggt cccggccggt tggccgaagc
    12421 actcgccgca gactctcctg cgaccggcac ctcctccgga gacattccac gtcgggcgtt
    12481 gggcaaaacc ggcgtgcagg tctcggccct ctgtttcggc ggcgcccatt ggggccgcat
    12541 tcaggatgat ggcgaggcga ttcgcttgtt acacgcggcc atcgatgcgg gcgtaaattt
    12601 tttcgacaat gcctgggagt acaacggcgg acggtccgaa gagctgatgg gcaaggcgct
    12661 gcagggaaaa cggcagcagg tagtgctgat gacgaaagtc tgctcgcacg ggcgtgacaa
    12721 gaaggtggcg cttcagcagc tggatgagtc gctccgccgg ttgaagaccg attatctcga
    12781 tctctggcag atccatgaag tggtctatga agatgatccc gatcggcatt tcgcgcccaa
    12841 cggcgcgacg gaagccttgc tggaggcgaa gcgacagggg aaggtgcggt ttatcggatt
    12901 cacggggcac aaacatcctg atatccacct gaagatgctg tcgcatgact ttccattcga
    12961 tacctgccag atgccgttga acgtcttcga cgggacctat cgcagctttg agcgggaagt
    13021 gctcccggtg ctgaaccagc ggggcattgc gccgttgggc atgaagagtt tgaccggtaa
    13081 tgccgagccc atcaaacaag gcatcgttca gcctgaggag gccatccggt acgtcttgag
    13141 cttgccgatt gcgtcgttag tgagcgggat cgactcgccc caggttctga aacagaacct
    13201 cgatatcgcg cggcggttta cgcccatgac catcgccgaa atggagggac tgcgcgccag
    13261 agtcgcgatg tttgcgatgg acgggcggta cgaactgttc aagtccacga atcgctacga
    13321 cggtcccatt ggccgccagc agcacggaat ctcttgaccg gttcagcgtg gtgcctaggc
    13381 acaggtccgg cactcgcctg tgaagacgcg agcgccggcc tatgttgggt tagatgtatt
    13441 cgatcacgca gtgaccgttt cctcggtcac tcgttggact cgatcctcta acgcacttgc
    13501 cagaaaccca ctgtccgcca atcgaacagc cattctcgcc tccctgcgca gatccttgct
    13561 caaagccatc aagccctctt ctgttcctgt gcggatggct ttatccagga cttcatctgc
    13621 agccggcttc cccgggaacg tcaatttggg attgtgtggg ccgacctcat gcaggagttg
    13681 tctgagaatg ccccctgcga cgtatcgctc gaatggtagg tcgatgagtt gaaagcgatc
    13741 gaagagcatg ggccattcgt ggcgcggaat tttctctttg aagatcggtt ctttaaagat
    13801 aaattcgctg actgtgcaac gtgatgctcg gccgccgagc gcatcgatgg cttcttctcc
    13861 gaaacgcgtc aggcttgccg caggagacag ttcaaccata cggtctgtcc agagaattga
    13921 ccaccaagcg gcatttctca tttcaatttg tcgtgccgga ggagcgagcc agactccgca
    13981 attcagaaag tacgcgtcga tcttttttaa cgccagctgg ccggctggtg tttcatcgaa
    14041 cccggagtat ggcgacggag gagcaaatcg gcccgtcagg ttgatgtcga accaatggtg
    14101 ccaggtggaa tcggcaagaa tccggccgac atctacattg tgaccgttat aggccgatat
    14161 cactccgatt tcttgcccat gtttggtggc gttcgggtct ttaattcttc cccatgcaat
    14221 gacttcagga gtctcttgat ggccgccttt ggttggccat gcggggtcgc ctgatactgg
    14281 tgtgggggcg agagcttcac cttcgtgctg atggtctggc aggaaattga tcggcccgtc
    14341 gggtccgcat aacacggggt ggggacgata gcgcctagtc aaaagcaagg gggaggcgat
    14401 ggtgtagcgc ttccaacgta ttgattgtgg tgtatcatcg gattggtcgt cgaaatcgaa
    14461 tgtagatcct gcatcaggtc catcttcaag tgtggtgttc cacgtcggtc cgtaatccgg
    14521 cggcgcagga taccgtctca tgacgcccgc gcgcgggatt tgtccggaga ttccccttcc
    14581 caggttgtca tgatcccccg tgaccagaac ccctccgaac ttcggccccg ccatgaactg
    14641 tgtcaggagt gcgacctcag ccgcagtgag atttggggtc gactcaatac cgaagaacca
    14701 gatctcatca tacttgttca taatgtcgag tgcgggatcg gtcaactgtc tggcgccggc
    14761 aattgtcgcc gaagggtcgc ctccggttcg gtgagcaaag tcgatggcga agtcgacata
    14821 agagtacgca cgagtcttta atagattgta gacgtactga aggccaagga atgatccgcc
    14881 gttgaagtgt acgctgccgt ccgcgtacat gagaatcctg accttagcgg gacgacgcca
    14941 ccaggggaaa tgaagatccc aatcgatcgc tccccagcgt cgacgaatcg actgttgcag
    15001 aatttgttca tccgagaatg aatgtgccat aagacctcct tgtgtagtca aaagctcgtc
    15061 atgagccctg gttaaagatg agactcgttc gagtcaccac gctgattgag cgctgcatca
    15121 ttgaacgaga atgcgattca ctagctagca agacctgctc cacaattgat gggaagaaaa
    15181 acccattaca caatcacaga gttgaaatac ggggtttgag aaatgtgaat ttctgccagt
    15241 gaatactggt ttattgattc agatacattg agtatcgtgg cggatacgca ttggcaatga
    15301 tggcatgctg tggcgacgga tcaacggaag atcggcaaat tcgaacgggc tatggcgtgg
    15361 gagaaagggg ggaatttgat gaaacgacta gaccaccatt ttaggaacat ccctgaacag
    15421 cggttagccg ctcatcgcca ttcgacggcg ccgaagccgg aatccccgag gatgacatac
    15481 atcagactga cggccgtgac tgtctgattg cgaaattcta cgctcggata atgtgcatcc
    15541 cggtgggaga gagaataccg aagcgccacg ccgtgccggt cgaacacccg aagcgtcaat
    15601 gaagattctg cccggacgat attctcctgc ccatgccgtt ctggagagag aaagtcgctg
    15661 acgtaatatt cccggcccgt aatgtctagc atggcgcggt tcgcataaat caggcgaagc
    15721 gccagcagcg cctgcggtgt cgtcccataa tggtaatccc gttcttccgt gcgctgaatg
    15781 ctcccggccg ctccatatcc tgcgccaccc aagaatgttc cttgaagtgc cagttcgtcg
    15841 gctaaccagg actgccacac ggttcccagt gagagagcgg tgctggagac ccggaagact
    15901 tgcggcgaga tatagtcata gctcccgaac aaaccccaga ttccgcgggt tgtgtcgccg
    15961 gatgcgtagg tcttccccgc gagcagcccc cgtgaggtga tggtttccag ggtattggcc
    16021 gtcgcggcgg agacatgaaa atcaaaatag tcgaacgggc gtgcgtagct gtagcctggc
    16081 ttgccgggta gaccgtacgt cagagtgaat tctcccaccg cgccgtgctc gttcacgttc
    16141 gacgccacat tgtggctgct cgaggtcagc gtgcctccac cagcgagacg aatgaacgtc
    16201 gcgggccggt tactggggta gaccgcatcg aagcggttac cgaataccag ccgattgaat
    16261 ccggtgggcg gtgaaatgat ggcggcgccc agttcgcgcc aaaagcccgg gcggccatcg
    16321 tctgattcga gcaggagatt ggccattctg aataatggct cgcccaggaa tgttccgccg
    16381 atgggggtcg cgatcatgtc attgatcgaa ggattcgttt tttcgccgcc gatttcccag
    16441 aggaaactgc cggcgacgct atacagcgac gactcccaaa agttgagtcc ggatgagcgg
    16501 gccagcccaa agtagatgct gccgctgtag gggtgcagga attggttgac ggaaaactgg
    16561 tcgttgtcga gcacccattt ggaatcggtc aggtgttgac gaatggtact gccggtcgtg
    16621 cggtaatctg acatcggttc ggtgaagtgt cgatcaaatt ggttcaacag gaagagatac
    16681 gcgagaattt ccgcagcggg gatcagataa ctgcggccct ctctcgtctc ccaattgagt
    16741 gccgaggacc ggcctgacgg attcgacgga ctttctgtcc gatcagcgtg attgactggc
    16801 ccgaccagat tccgttggcc attgtccgcg gcgggtgtga gcggctgatc ctgagacagg
    16861 ctcatgcccg gggacattga agccagcgcc gaaaccagcg tgatcattcg gataaggtga
    16921 ttgttgcgca ggacggacag catgctgtgt cagggctccc accgtgagtt gatcccatca
    16981 gtccgcttcg ggacactcgg ggaaacccta gctcctgacg cagaatgcct agttgcgcag
    17041 agagatgccg tgtcagcggg gttttatcag ccgctgaagg ctgctgccgg cagcaaggcg
    17101 ggcgaactgt accttcaagc cgttgacccg ggcgaggtaa ctgctggcgt gatgatcacc
    17161 gcatttctgg tggggcgcga ggtggaaccc gcgcgcaacg aacgcgtgcc cggctcccgc
    17221 tccgcagagg tggatgacag ccgcaaggtc ctgcttctgt tgcctgctga tagaggcgct
    17281 tcgccgggaa ccgatcgccg cggcgacctg acgatcgagc aaggcggcgg tcagttcgat
    17341 ggcatggctc ggaacaatgc gtgtgtagaa gctgttgaac caacaagcat gcatatcatt
    17401 ccaggggccg tcttcaacca ccacatggtt gtggatgcag tagcgtttcg cttctcggaa
    17461 tgtgccatcg gtcaactgga acatcccgac ggcgctagaa gccggtcggt accaatcgaa
    17521 cggattccag gacaatcgcc agcgccaata ggttcgtgcc acgggattgc ccgatccttc
    17581 cacttgtgcc agcgcggcga gaaggtccgg ggtgatgatg gccgtcgaat gctcacgaaa
    17641 gagcggcccg tattcctgcc aggtggccgc gggattctta tccagcgcat cctctagagg
    17701 aaacaacact tcggtcggct tattgatcgc gtgataggtc cagttcaggg ttccccagag
    17761 acaggcgatg aggatgatgc cgataagcag acgcgggagg ggatgcgtat tgccccacgc
    17821 gcgaaggaac gctcgaaggt cacgccagcg gcgtccggtg aaccgccaga gcgaggtgaa
    17881 tgtgaggcgg cgacgggagc ggcgtctgtg gggggaatat gtgccggcac gatgagtcac
    17941 tcgaggcgcc atcgcctcac tatacccgaa atgggctcat gagctactca gttattggct
    18001 acccgtatgt gggatcgctc cccggaagcg aggcctcgca gagaactctc gctgatgcgc
    18061 gtcgttatcg cccgtggtgg ccgccgccgc tgtgggaatg gccgcctccg ctatgcccgg
    18121 cataaccgcc ggaagatcgg ggcgccatgc tgaccgatgg actgtgttgc ggcggtactg
    18181 aggaaaggct ctgaacattc ggcggggtgg ggcgccagaa atgattcggg tggacctggt
    18241 aaggcggcgc gtgcggcgtg tattgcggag tcgagggaat cgatcgtggt gtcgggatga
    18301 ccaccacgtc acctaccttg gcctgctggc cctggctgtt gaggagtggc gcggcctgct
    18361 ggtgatgcac gtgaggcaca gggggaacta acagcgaggc gcgcggggcc gtggagaccg
    18421 gcggtgatgc gggtggagcg ctgaggttcg ccatgatggt tctctgcgcc agcgggaggt
    18481 ggcgatgatg cggcgaaagt cgctgcgctt gcagcaacag gccgttgatg cctgatacgc
    18541 cgatccatgg gtatgagtag aagcccaatg ttggatatgt ccaactcgtc caggcctgcg
    18601 acaggagcgc gttcgcctgc aactggtcga gcatatcctg acgttgatcc gtgtattgct
    18661 gcacgtcgta aggcgtagaa gcggcggcca gcgcgcgatt ggtgtcgtcg acctgtgcct
    18721 ggagtcgatc ggtttcagcc cggagcgcga gaagttcttg ccgggcctgg tcgttctccc
    18781 tgagcgcggc aatggcctga atgacgtcct gcggctcaac ttctcctgtg atgtccacac
    18841 gaatcacgac ttaatcctgt tccagcctgg tcgtcaccgt ctggtcaatc accctgacga
    18901 ctccggcggt gaagctacgg atatcatcac gcgtcacgtt caagtctttc acttccgtga
    18961 tgcgctcgac gtaggttgcc acctgttcca gcgcgtcttg cttcgcggct tccgtcgcga
    19021 ggcgaacggc atcggcgcgg ttgtcgtgat cacccatacg gtattcaccc ctggcggtga
    19081 tcgtgcgcgc ttcggccgaa cgcggacgaa gttcggatgc catgtcaggt gcaggcgttt
    19141 ccggacgtgc cggtgtgtcg aagctgcgct gggtcagctg cgggcggtat ttctccggga
    19201 ccgatgccaa ttcgttggta aaagtctgca cgccctcgtc gttcgtgtag ctgtaaatgg
    19261 tcgtcgaggc gaaagaggga gccgtaggaa gcacggagag ccagaggacg aggagtgcgg
    19321 cggtggtcgg tgtgctgcgg gagaagaaca tggtacagcc tcccgttcgt ctacagggtc
    19381 aggataacac aaggagggca accgattctg ctggccaggg cttagatatg ttgggcgata
    19441 cgagggcggg tttgtcgtgt ggggaagtcc ttctacaggg agtgtccata gaagagcggg
    19501 atctcgggat ttactggctc ctcctccaga tcgcgctagg atggaatcat cctatgctgg
    19561 tcgtcaaacg aatcatcgct gttgtgtttg ggctcgtccc gcttgtgctc attgcggctg
    19621 gggtcgcaat ggttttccgg gaactccggc ccactgatcc gttgttgtat tccgtgcagc
    19681 aggatgggga actccccgag gccttcatgt ttgcggctgt ggggtgcgcc ggattattcg
    19741 gctgccaccg tctgtggcga gccgatgccg gctggaagtg gaccctcatg ccgattgccg
    19801 tgatggtggc tgcgatagcc attcctaatc ttctctatgg acaccatgga tcgccgtcgg
    19861 atcgagccta ctccaatatg ttcctgcggc tgggcacgtt cgccgtttcc tcaaagcagc
    19921 tggcccagga acaaggccag tttacctgtg atccctccgt gaaactattc gggctatctc
    19981 gtttcaccca aaacggtcag cctcttccct atgtgatcca ctgtgtgctc gatgcgactg
    20041 gtctggcact ggccactccg cctgaacggc ccggaacgct ggtcttcgcc gtcagtcctg
    20101 acaggaagca ggcctggttt gccgccacag ttttagcacg ccggaccgat cggcatgcga
    20161 cctggttgag gcagcaaggc cagccgcggg ttatcgcgtt cagtgtgcag gagaagaact
    20221 aagggagacg gtgcgctcgg acgttcaatt ttgttcgcct tcgtcgatca tctaatctaa
    20281 tttcctggaa atggtctacg ctggaattga agccttcaag gcaacttgtg tatcctacgg
    20341 cccgttgtcg ccaccctgct ctacgaggtg ccagcatgag ccagccttca ccgtctgttc
    20401 cttccaacct tttcttgctg tgcatttcgg gcccggatct cggcaaacgc atcgcattgc
    20461 gtgatggaga actgctgatc ggccgatctc tgcaatgtga tgtgctgagc gacgatcagg
    20521 atgtggtgga gcggcatgcg gtcgtgctgt gggagaacgg ccaactcatc tgccgggcag
    20581 tccaaggcat cgtgtacctc gatggacaca agacgatgga gtccgtcctg acgccgcagc
    20641 agcagatacg gatggggcgg tccttgtggc aactcaacgg gccgacgccg gggagaggct
    20701 ccggagggtg gatcgaagat ctgagcgatc gcatcagcga ggtggcaggg gtagagcggc
    20761 ttcaaggctt caatgcgcgc gacatgtttt ccgacgtgct gcgcaagcgg accgacgagg
    20821 aaattgaaga gcatttcacg gcgggaacgc taaccaccac accgccgatt gaaaaggtga
    20881 taaccggctg gccgaagccc tgggtctttt ttaaaacctt cattctctcg gcggtcgtct
    20941 atctggcgtt tgtgttcgcc atgaaggaat tcaataacgc caatctcgtg ccggggctca
    21001 ttatgacagg tgcgttcctc attccgtcgt ccctgctcat cttctttttt gagatgaacg
    21061 tccttcggaa tgtttcactg tatcaggtcg tgaagatggt gatgttcggc ggcgtcacgt
    21121 cgctgatttt atcgctcttc cttttcaagt ggacggacct cgacagttgg atgggcgcga
    21181 tgagcgccgg ggtcatcgag gagacgggga aggcgttggc gctcctgctc atcatcaaca
    21241 atcaaaaata ccgcacggcg cttaacggtc tgttgtttgg agcggcggtg ggcacgggtt
    21301 tctccgcgtt cgagtccgcc ggctatgccc tcatggccgg gctgagcggc ggacagtcgg
    21361 ctatgttgca cagcatcacg gtgcggggtc tcttgagtat gctgggcctg catattgtat
    21421 ggacctccat ggtcggggcc gcactctggc gcatcagggg gaatcgatcc ttcaccattg
    21481 agatgctgta cgacaagcga tttctccgca tcttcggatt ggcggtggcg ttgcatatgt
    21541 tctggaacgc gccgttcaat ctgccgtttt atctcaagta tattgcgttg ggcttcatcg
    21601 cctgggtcgt gaatctggcc ctggtgcagg ttggcctcag agaagtgaag gcgttgcaag
    21661 aggcacaggc gtccgaggct tcggattcga gattgagaac ggcgtagggc acatcgcctt
    21721 tgcatgagcc atggaggatc agcttgaagg aggagaatcg ttggatcgtg agccagctgt
    21781 cggagacacg gctagctgtt cgacgaattg tcgtgcttct tccagtgtca tatctttcgt
    21841 catgcgaacg agtttgatcg cgtcgagttt gcggccttga gccaaagcgg ctgttaggct
    21901 gtccagcaag aaattggttc gttctgcgtt catttgcatc aggcgacgga tcgtaatcgc
    21961 caactcttca tactctcgcc tcatcccgcc tgcgtaggct ctcgagagcg gaatttccct
    22021 ctcgtctgtc actagcgcca gccgcactaa gggagcggtt ttcgtgcttc cgatcgcggc
    22081 ttgtactgta agcgagcgca ggcatgaaaa aggcatacgg ccttcatcct ttgccatgag
    22141 gctacggcgg ctccaccgca cttccttcaa atggggatca aagacaaaac gatttcgttc
    22201 gtagctgaag aacgcgccga ccaaaaacat ggctgacccg atcagcggcg tggcatcgtg
    22261 cgcggtcgcg ccaccaatca accaggaccg aaagaccgga acggcgcaaa gcagtgcggc
    22321 gccggtcagc atcccaacaa taaaccgcga gtcaatggtt acaaccagcg tgccgtccgg
    22381 ttcagtgtgg tgcttcatag agagaagggt agcagacgaa cgcctggaca ggtaggagtt
    22441 cagatatttt ggttgaggtg gtgtatgccc aagaaactga gcgctggaat tgtgctctat
    22501 cggagaatcg gtggagggct gcaagtcttt cttgttcatc caggcggacc gttctgggcg
    22561 aagaaagata gcggagcttg gtcgattccg aaaggtgagt acatcgaagg cgaagagccg
    22621 gagactgttg cgcgacgcga atttcaggaa gagaccggcg gtgagctaac gggccggctg
    22681 caggccctca cgccactcaa gcagccaagc gggaaggtga tctctgcctg ggccgtagaa
    22741 ggcgacattg atcccgcaga attgaagagc aactcatttt atctcgaatg gccgcctcgc
    22801 tccggaacaa ttcaacagtt tcccgaagtc gaccgcggcg cttggttcga tctacccacc
    22861 gcgcaggaga aaatgctcgt tgggcaacgg ccgttccttg aggaattagt gcgcttcgtg
    22921 aaggagtagg tctggctcca taattctgat ctcttgtttt gttcag
//
LOCUS       DAOQPD010000061        22839 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1076_length_22839_cov_24.442065, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000061 DAOQPD010000000
VERSION     DAOQPD010000061.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 22839)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 22839)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22839
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1076_length_22839_cov_24.442065"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..310)
                     /locus_tag="PK063_13425"
     CDS             complement(<1..310)
                     /locus_tag="PK063_13425"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98099.1"
                     /translation="MADRAVGIPIVKEGLPFVGGLAGATLLFGLAGWTIPTVVAAGFL
                     LFTAWFFRNPSRTIPQQPNVVVSSGDGKVIAIEEEFEPRYLKEKSIRVTVFLNVFDVH
                     V"
     gene            complement(360..1373)
                     /gene="ilvC"
                     /locus_tag="PK063_13430"
     CDS             complement(360..1373)
                     /gene="ilvC"
                     /locus_tag="PK063_13430"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HMZ98100.1"
                     /translation="MKIYYDKDADLQLIRGKKVAVIGYGSQGHAHSLNLKESGATVVV
                     GLREGSSWKKAEASGLKVMPVADAVKASDVIMILAPDEAQAAIYRQDIAPNLKPGSYL
                     AFGHGFNIHFGQIVPPADVNVFMVAPKGPGHLVRSEYTKGSGVPCLLAVHQDPSGNTR
                     QVGLAYASAVGGGRAGIIETNFREETETDLFGEQAVLCGGLTSLIQAGFETLVEAGYA
                     PEMAYFECLHEVKLIVDLIYQGGIANMRYSISTTAKYGDITRGPRVVTEQTKQEMKKI
                     LGEIQSGQFAKEWVLENQANRPVYNALLKKGEGHPIEEVGGRLRSMMPWLKKDQLVDK
                     NKN"
     gene            complement(1440..1958)
                     /gene="ilvN"
                     /locus_tag="PK063_13435"
     CDS             complement(1440..1958)
                     /gene="ilvN"
                     /locus_tag="PK063_13435"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HMZ98101.1"
                     /translation="MEHIISVTVENKFGVLSRVAGLFSGRGFNIESLSVAPTLDPSMS
                     QMTIVTSGDERIVEQIVKQLNKLIDVIKVVDLNESEFVSRETALIKVHTKAEDRAEAL
                     RIADIFRANVIDSTPSTYTIEVTGDPKKLEAIINLLQPLGIKELIRTGRVAIAREAIR
                     PALSQPKKLARE"
     gene            complement(2001..3779)
                     /gene="ilvB"
                     /locus_tag="PK063_13440"
     CDS             complement(2001..3779)
                     /gene="ilvB"
                     /locus_tag="PK063_13440"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005948 - acetolactate synthase complex
                     [Evidence IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009099 - valine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HMZ98102.1"
                     /translation="MKLTGSEILIECLKAEGVKTIFALPGGVVLKIFDMLHQQKDIEV
                     VLTRHEQGAGHMAEGYAKATGKAGVCLVTSGPGMTNVITALADAYMDSVPLVCISGQV
                     STSLIGNDAFQEADNIGLSRPCTKYNFLVKDVNDLATTIKEAFYIATTGRPGPVLVDI
                     PKDVSMAKADFTYPSSVSIRGYNPTYEGNKWQIKQAAEAIMKAKKPILYVGGGVVFSQ
                     ASKELLELAEMTQIPVDMTLMGLGAFPGEHPQSMGMLGMHGTYCANMAVHYSDLVIAV
                     GARFDDRVTGKVSEFCPFAKVIHIDIDPTSIRKNIHVDIPIVGDCKAVLRELNQILRA
                     TVNGNQKDLRKPWWDQIREWQQAHPLAYQQEPDGAIKPQHVVKRLYELTKDRDPIVAT
                     DVGQHQMWTAQYFKLARPNRWLTSGGLGTMGFGFPAAMGAQAAFRDRLVLCVAGDGSI
                     QMNMQEMATAVVSKLPVKIIILNNRFHGMVRQWQDLFYEGRYASSYLDTTPDFVKLAE
                     AYGAVGLRAGKVGDLDAVLKEAISTDRPVVVDVPTYPYENCYPMIPAGGCNHEMILAD
                     PPELKQRMAGVPSTGSDENKDTILTA"
     gene            complement(4272..4695)
                     /gene="rnpB"
                     /locus_tag="PK063_13445"
     ncRNA           complement(4272..4695)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="PK063_13445"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            complement(4757..5647)
                     /locus_tag="PK063_13450"
     CDS             complement(4757..5647)
                     /locus_tag="PK063_13450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HMZ98103.1"
                     /translation="MKMKSNREGWSKSARPSNLLWLCFGIVTMLVTTGCQTNPYTGRW
                     QLMMMPMSQEVQMGAQAYADVKSDPKMRPSTDPREIEPVKRVAARVIEAAKRSKYSDV
                     ANEFEWEVTVIKDDKTMNAFALPGGKIAVYTGIFPVAKTEAGLAAVMGHEVVHALARH
                     GGERMSQNTLAQTTLQAIGIALGVSGANPVLSQAGMAALGVGAQVGVLLPFSRKHESE
                     ADYVGVLLAADAGYDPREAIQLWQRMGEMSGGKSPSEFMSTHPSHETRIQQLEEWMAE
                     AMPIYQSKPPAPNHELPALH"
     gene            5733..6392
                     /gene="rnhC"
                     /locus_tag="PK063_13455"
     CDS             5733..6392
                     /gene="rnhC"
                     /locus_tag="PK063_13455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HMZ98104.1"
                     /translation="MPITTTLFSLNRIGIDESGKGDYFGPLVIAAVFVTPASEQDLAL
                     MQVRDSKKISDGRILEMAPDIRTVCPHSIVAIGPQRYNELYAKINNLNRLLAWGHARA
                     LENLLQQVDCDLAIADQFGDERLILNALQEKGKQIRLVQRTKAETDLAVAAASILARA
                     EFLLRLQRLSQELHTTLPKGASPAVELAGRMVVKKYGRDRLSTVAKLHFKTTQQVLND
                     T"
     gene            complement(6389..7165)
                     /locus_tag="PK063_13460"
     CDS             complement(6389..7165)
                     /locus_tag="PK063_13460"
                     /inference="COORDINATES: protein motif:HMM:NF014630.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-type zinc ribbon domain-containing protein"
                     /protein_id="HMZ98105.1"
                     /translation="MNPQLSPLIELQKLDLRIADLKEQRRRIPERLEVNEAPLREARR
                     TVQDASASIETLNKERRSHEKDLEAHEDRIGKMKDRAAQLKTNQEYQAHLFEVELANK
                     KRGEIEEKILLAMEQIEQTQRMIASAQVQLKDSEALFSKEKAVLDEKDRVLAAELAEL
                     EAQQKELSGRVEKGLLARYNKLKATRKDQALALIKDGICIGCRLQVPPQLISQVKRGD
                     DVYTCPYCYRMLYWEGEPVPEGKRPLVQDQAKDFELGESV"
     gene            complement(7243..7319)
                     /locus_tag="PK063_13465"
     tRNA            complement(7243..7319)
                     /locus_tag="PK063_13465"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7283..7285),aa:Ile,seq:cat)
     gene            complement(7432..9237)
                     /gene="rpoD"
                     /locus_tag="PK063_13470"
     CDS             complement(7432..9237)
                     /gene="rpoD"
                     /locus_tag="PK063_13470"
                     /inference="COORDINATES: protein motif:HMM:NF004208.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HMZ98106.1"
                     /translation="MPKQELLGEVKKLINLGKEKGFLTYDDLNSTLPADVVSSDQFST
                     IMTMFGEMDIEIVESAETERAPKAAEGEEAIEESEESDSSEENEKEIDLTPGALSRTD
                     DPVRLYLKEMGSVALLSREGEIEIAKRIEEGKKDIATVVYGLPMTLEFVLNLRDQLKN
                     GKIDVREIVPVVETEEDFEEEAVEKDYEELRVKTLDSLNAVRKVSASLKDLYDKARHV
                     GADPEKQKKLRKQIDTVRGQVVDKMESVNLHGVLKDRMTQRVRDLNLLFRQSEREVTS
                     CQRRLGVGGEAGAELLRKLCRTHKDVLAVKRRTGLSEEVLQDIKKHYQAAKGRIRQLE
                     EEEALISAEEIKDAVKHLDVAEEKVKRGKAELVEANLRLVVSIAKKYTNRGLQFLDLI
                     QEGNIGLMKAVDKFEYKRGYKFSTYATWWIRQAITRAIADQARTIRIPVHMIETINKL
                     IRTSRHLVQKLGREPTPEEIAERMDLPLDKVRKILKIAREPISLETPIGEEEDSHLGD
                     FIEDKKAVSPLEAAIRYDLQRQINGALETLTPREEKVLRKRFGIGEATDHTLEEVGQD
                     FEVTRERIRQIEAKALRKLRHPSRSKKLRSFVESL"
     gene            complement(9241..11085)
                     /gene="dnaG"
                     /locus_tag="PK063_13475"
     CDS             complement(9241..11085)
                     /gene="dnaG"
                     /locus_tag="PK063_13475"
                     /inference="COORDINATES: protein motif:HMM:TIGR01391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of RNA
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HMZ98107.1"
                     /translation="MGQGLISDDVINQIRDRVDIAEIVGQHVALTRAGQNLKGLCPFH
                     QEKSPSFTVSSSRQIFHCFGCGAGGNVYTFLMRLTGAAFPEIVRDLGRKVGVDVPEST
                     GGVSNEARTQLGRLERLNAAAGAWYHRMLTQGPTGAQARAYLDSRGIQQHTTAQFNIG
                     YAPPEWDGLTRAMLKEGFAPADLVAAGLSIPRDQSGSQKTAVSGHYDRFRSRIMFPIT
                     DLRKRVVAFGGRILGDGMPKYLNSPETPLFKKGQTLFALDAAREAAGQQHTLIIVEGY
                     FDAIALHQAGIRHVAATLGTALTAEHITVIRRFASNIVLLFDPDQAGVRAALRSLDLF
                     VNSGLSVKVVSLPEGDDPDTYVRQHGAEGFAALHRAAPSLLDFAIEHSLRTAESGSVE
                     DRIRAVDAVLRILQKSAHPIEREERIRLVAERLGLSQQRLIDRYPTLVSEEQRRPDRT
                     AKAPSISVPSRVKPNPEERDLAHLLVQGSLSAADLRKLSPDAFSAPAYKRLIECALQH
                     LADDGRVSVRTLLDALITDEVCGSLVSELSMQEQHYDDVPAHIAGCLETLERRGRERT
                     MGLLIQELKVAERERREDEVHRLNGLINDMRIRKAGVMPVALTSAVKE"
     gene            complement(11217..11561)
                     /locus_tag="PK063_13480"
     CDS             complement(11217..11561)
                     /locus_tag="PK063_13480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HMZ98108.1"
                     /translation="MDNCIFCRIVNRAIPAKIVHEDDRVLAFEDVNAQAPVHILVIPK
                     RHLAAVQNCQDGDQALLGHLLMTCSKVAAMKNLAESGYRIVTNTGADSGQTVFHLHLH
                     VLGGRHMAWPPG"
     gene            complement(11554..12237)
                     /gene="hisIE"
                     /locus_tag="PK063_13485"
     CDS             complement(11554..12237)
                     /gene="hisIE"
                     /locus_tag="PK063_13485"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004635 - phosphoribosyl-AMP
                     cyclohydrolase activity [Evidence IEA];
                     GO_function: GO:0004636 - phosphoribosyl-ATP diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HMZ98109.1"
                     /translation="MSSDSRSMTFDGQGLIPAVIQDWFDGTVLMVGYMNQEALTKTLA
                     TKSVHFWSRSRQKLWEKGETSGHFLRVKDLFVDCDRDTILVKAEPVGPTCHTGERACF
                     FSRMSADGRAEPGKTQDAGGGILERLYQTILARKAAPQPDSYVSKLLQGNVDRILKKV
                     AEEAGEVIIAAKNQKRDEIIYETADLFFHTLLVLGYHDVTLSEVYRELGARFGKSGIR
                     QAPEGESRG"
     gene            complement(12250..13020)
                     /gene="hisF"
                     /locus_tag="PK063_13490"
     CDS             complement(12250..13020)
                     /gene="hisF"
                     /locus_tag="PK063_13490"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HMZ98110.1"
                     /translation="MLTKRIIPCLDVKDGRVVKGVSFVNLRDAGDPVEVATIYDREGA
                     DELCFLDITASHENRKTIVDVVERTAARVFMPLTVGGGVRTLDDIRTLLNAGADKVSI
                     NTTAVQKPEFVREAAQRFGTQCIVVAIDAKRAEAAGRWQVYTHGGRNATGLDAVEWAQ
                     RMAEYGAGEILLTSMDQDGRQNGYDLALTAAVSESLSIPVIASGGVGTLEHLYDGLVK
                     GKAEAVLAASIFHYRTHTIQQAKAFLRDRGVPVRIGAA"
     gene            complement(13091..13816)
                     /gene="hisA"
                     /locus_tag="PK063_13495"
     CDS             complement(13091..13816)
                     /gene="hisA"
                     /locus_tag="PK063_13495"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003949 -
                     1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HMZ98111.1"
                     /translation="MRVIPAIDLKDGRCVRLRQGDMAAETVYSEDVPSVAKRWQEQGA
                     DLIHIVDLNGAVDGEPKNLPQIESAMKAVNVKVQVGGGIRTIDTVRKYLQAGVARVVL
                     GTAALTDRAFLAQACREFPRRILLGLDARDGKVAVKGWTAVSETKAIDLLRELADHEL
                     GAVIYTDIARDGMLNGPNLAALGEVVNCAAFPVIASGGITRVEDLQAVRALGPRVEGA
                     IVGKALYDGKLDYRAALAALGNR"
     gene            complement(13839..14576)
                     /locus_tag="PK063_13500"
     CDS             complement(13839..14576)
                     /locus_tag="PK063_13500"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98112.1"
                     /translation="MSTCIPRTLFILLSVVLTTGCSGTKVTSKASPQAGKYQVRNIVL
                     IPFETMATPQAIETSGPSFPVPSGVRRSDMAVGVPPTTDQAVRRTNLVPPGAGEKITD
                     LMWAKLKGKPGLQVISPQEAMGAARDLSRGSGSVETIPAHKIAQRLKADAALSGKVLV
                     YQERVGSRLGADPPAAVGFEVKLVAPDGMVLWEGNYYEKQRPMTEDVLGFVQRYGTFV
                     TAEELAAYGATELAEAFPFGAAAGEGK"
     gene            complement(14573..15181)
                     /gene="hisH"
                     /locus_tag="PK063_13505"
     CDS             complement(14573..15181)
                     /gene="hisH"
                     /locus_tag="PK063_13505"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HMZ98113.1"
                     /translation="MIAIIDYGMGNLRSVSKAFEAVGHQAVVTREARVIADASHVVLP
                     GVGAFGDCMANLERYELIGPIHAAIQSGKPFLGICLGLQLLFAESEEFGTHKGLGIIP
                     GRVKRFVLDASLKVPHMGWNDIRIMRPAPIFAGIAPGSYCYFVHSYYVEPADSAVVAT
                     VTDYGAPFASAVWKDNVVACQFHPEKSQAVGLQVIKNFGAWT"
     gene            complement(15246..15851)
                     /gene="hisB"
                     /locus_tag="PK063_13510"
     CDS             complement(15246..15851)
                     /gene="hisB"
                     /locus_tag="PK063_13510"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004424 - imidazoleglycerol-phosphate
                     dehydratase activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HMZ98114.1"
                     /translation="MKNTGVPRQASLHRATKETDIRVEWTLDGTGQGKIDTSIRFFDH
                     MLDLLAKHGFFDLTVQAKGDIDIDEHHTVEDVGIVMGKALHQALGEKAGIKRFGWASV
                     PLDETLAQVTVDLSGRPYLVYNVNLPDRKIKTFDLGLFEDFFQAFVTHGGLNLHINLQ
                     YGRNPHHIMEAIFKALARALDQATLPEERLSGAVLSTKGSL"
     gene            complement(15848..17131)
                     /gene="hisD"
                     /locus_tag="PK063_13515"
     CDS             complement(15848..17131)
                     /gene="hisD"
                     /locus_tag="PK063_13515"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004399 - histidinol dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HMZ98115.1"
                     /translation="MTILESTDRAFAKALRKITARSRSQAATVEKSVRAILQAVEKGG
                     DRAVLRYTKKFDRVSVTLDQIRVTPEEIKEAYYHIRKDEGDSLRYAAERVRQFHERQR
                     TKTWMYQEENATLGQMVTSLDAVGVYVPGGKAVYPSSVLMCAIPAKVAGVRRIVMCTP
                     TPKGEINPYLLVAADIAGVDEIYRVGGVQAIGAMAFGTKSIAKVDKIVGPGNMYVATA
                     KRLLYGTVGIDMVAGPSELLVVADDDAKPAHVAADLLCEAEHDEDAQVYLVTTSASLA
                     KEVVRLIQVQLKGLQREKIAAKSIARHFVAFVVPSMDEAIEVANDIAPEHLTLSVDRP
                     FDYLEQIRHAGALFLGRYTPPAVADYVAGPNHVLPTGATARFFSPLSVNDYVKVSNIV
                     HYTREELTKAKDHIVRLAHIEGFDAHAKSAQSRFS"
     gene            complement(17217..17885)
                     /gene="hisG"
                     /locus_tag="PK063_13520"
     CDS             complement(17217..17885)
                     /gene="hisG"
                     /locus_tag="PK063_13520"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003879 - ATP phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HMZ98116.1"
                     /translation="MKARKSQDEKPKGLTIALSKGKLLGPVLHLMKAAGYYSPGLSVE
                     SRKLVFDCAANNATFLIVRPTDVPTYVEHGAADVGVVGKDVLLEQGSDVYEPLDLKVG
                     ACRISVAALQGQPSPDRWSSKVRVATKYPNVTERYFNQRGMPVEIVKLYGSIELAPIV
                     GLADRIVDLVETGSTLKAHDLAEVEVITHSTARLIVNRASLKLKHEPLQVLIDRLRTA
                     VAAE"
     gene            complement(17888..19144)
                     /gene="murA"
                     /locus_tag="PK063_13525"
     CDS             complement(17888..19144)
                     /gene="murA"
                     /locus_tag="PK063_13525"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HMZ98117.1"
                     /translation="MDQILIQGGRRLQGEVRTSGAKNAALPILASTILGGGECVLSNM
                     PRVVDVLTMGKLLRMLGIAVSQEGDQTVVQAEAIASTEAPYDLVRTMRASVLVLGPLV
                     ARLGEAKVSLPGGCAIGSRPVNFHLAGLEKMGAAVEIEHGYIKASARRLRGSRIYFDT
                     PSVTGTENLMMAAVLAEGTTVLENAAKEPEISDLAAFLVKRGARIAGAGTDMITIEGV
                     TELHGADHEVIPDRIEAGTYLVAGAITGGEVIVDRCRPEHMEPLLMKLRESGAELIEE
                     KERVHLKVTGRLKGTNVRTSPHPGFPTDMQAQFVALMAVAEGTSVVTETIFESRFMHV
                     EELRRMGADIRVEGNRVVITGKERLTGAPVMASDLRASAGLIVAGLAAEGTTEVSRVY
                     HLDRGYERLEEKLRILGASIERRKGK"
     gene            complement(19188..20114)
                     /gene="prmC"
                     /locus_tag="PK063_13530"
     CDS             complement(19188..20114)
                     /gene="prmC"
                     /locus_tag="PK063_13530"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: protein motif:HMM:TIGR00536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HMZ98118.1"
                     /translation="MRQQQLADAACSVSSLGELLRKSESRLDAAGIDQPALESAWLVE
                     HVLKLSPLMQRINTERGLTPEECEGVQVLVERRANREPLQYVLGTQEFCGRDFFVTPS
                     VLIPRPESVLLVEEAVRRCVQISDATIVDVGTGSGCLAVSVASALPTARVLAIDASTD
                     ALVVARNNMARYGVEARITCLQGDLLDPIGQEGLPNQVEVILSNPPYIPDGDVETLQP
                     EVRDFEPRLALAGGRDGMDVHRRLIAQAPAYLKPGGALLMEVGIGQAAAVCRHAEEGG
                     RLRTYVVLRDQGGIERVVCFEKKEESLSSSSS"
     gene            complement(20111..21193)
                     /gene="prfA"
                     /locus_tag="PK063_13535"
     CDS             complement(20111..21193)
                     /gene="prfA"
                     /locus_tag="PK063_13535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003202249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HMZ98119.1"
                     /translation="MEDGLIKKWEAMAARFQELTNQLMDPTVLNQPGMIHKLNKERTE
                     LEEPAQEFAAYSQAQKQLHEVTVMLQDSGTGADMKQLFAEESEHLTQQLLDIEARAKD
                     FLTPKDPRDEKNVFLEIRAGTGGDEAALFAGDLFRMYLKYAERNRLRLEVVDASETGI
                     GGYREVIALLEGKGAYGRLRYESGVHRVQRVPTTEASGRIHTSTVTVAVMPEVDEVDV
                     HIDPKDLRIDTFCSSGAGGQSVNTTYSAVRITHIPTGVVVSCQDERSQLKNRTKAMRT
                     LRARIVEAEREKQEAAIAQDRKSQVGTGDRSEKIRTYNFPQNRVTDHRVGLTVHKLDQ
                     VLAGDLEEIVQALRAHYEHLASLETK"
     gene            complement(21287..21493)
                     /gene="rpmE"
                     /locus_tag="PK063_13540"
     CDS             complement(21287..21493)
                     /gene="rpmE"
                     /locus_tag="PK063_13540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HMZ98120.1"
                     /translation="MQKGIHPVYREATVHCACGNTFKTRSTIGDIKVDICAGCHPFFT
                     GTQKIVDTEGRVERFKKKYAKKDK"
     gene            complement(21587..22834)
                     /gene="rho"
                     /locus_tag="PK063_13545"
     CDS             complement(21587..22834)
                     /gene="rho"
                     /locus_tag="PK063_13545"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017631298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HMZ98121.1"
                     /translation="MHLAELKQKSIADLNDVARDLKIEGAANLRKQELIFAILQAQTE
                     KNGVVFGEGVLETLPDGFGFLRAPDSNYLPGPDDIYISPSQIRRFNLRTGDIVSGQIR
                     PPKESERYFALLKVEKVNYEDPEVARDKILFDNLTPLYPEERLNLEFDREEYCTRVMD
                     LTTPIGKGQRGLIVAAPRTGKTMLLQAIARAILKNHKEVTLIVLLIDERPEEVTDWQR
                     QVKAEVISSTFDEPAQRHAQVAEMVLEKAKRLVEHKKDVVILLDSITRLARAYNTIAP
                     PSGKVLSGGLDSNALQRPKRFFGAARNIENGGSLTIMATALIDTGSRMDDVIFEEFKG
                     TGNMEVHLDRRLADKRLFPAIDISQSGTRKEELLVDRDRLNKMWILRKVLSPLGTMEA
                     MEFLMDKIGGTKTNQEFLQSMNR"
BASE COUNT         4740 a         7109 c         5896 g         5094 t
ORIGIN      
        1 tcacatggac gtcaaacacg ttcagaaata ccgtgacccg aatgcttttt tccttgagat
       61 accggggttc gaattcttct tcgatcgcaa tgaccttgcc atctccggat gagacgacca
      121 cattgggttg ctgtggaatg gtccggctgg gattccggaa gaaccaggcg gtaaatagca
      181 aaaaaccagc cgctacgacc gtgggtatgg tccaccctgc caacccgaac aacagggtgg
      241 cgcctgcgag accaccgaca aacggcaagc cttctttgac aatcggaatt ccgacggctc
      301 gatcagccat acccctccag gccctctatc atgctaccac gaagaatccg ccggttgagt
      361 tagtttttgt tcttatcgac gagttggtcc ttcttgagcc agggcatcat ggaccggagc
      421 cggccgccga cttcttcgat tggatgcccc tcgccctttt tcaacaaggc gttatagaca
      481 gggcggtttg cctggttctc caacacccat tctttggcaa actgtccact ctgaatctcg
      541 ccgagaatct tcttcatttc ctgctttgtc tgctccgtca cgacacgcgg accacgggta
      601 atgtccccat actttgccgt cgtgctgatc gaatagcgca tgttggcaat gccgccctga
      661 taaatcagat cgacaatcag tttcacctca tggagacatt cgaaataggc catctcaggc
      721 gcataccccg cctccacgag cgtttcgaat ccggcttgga tcagagacgt cagcccaccg
      781 cacaggaccg cctgctctcc aaagagatcc gtctcggtct cttctctgaa attcgtctcg
      841 atgatgccgg cccgtccgcc acccaccgcg ctggcgtaag ccaagccgac ctgccgggtg
      901 ttcccgctgg gatcttggtg gacggccaac aagcatggca ctccgctgcc tttcgtgtat
      961 tcggaccgga ccaggtggcc gggccccttc ggcgcaacca tgaacacgtt gacgtctgcc
     1021 ggcggcacga tctgtccgaa gtggatattg aatccatggc cgaacgccag ataggaaccg
     1081 ggcttcagat tgggcgcaat atcctggcga tagatcgccg cttgcgcttc atcaggggca
     1141 agaatcatga tgacgtccga ggctttcaca gcatcggcaa ccggcatgac cttcaaaccg
     1201 ctagcctccg cttttttcca tgagcttccc tcgcgcaacc ccaccacgac cgtggcgccg
     1261 ctttctttaa gattgagcga atgcgcatgg ccctggctcc catagccgat cacggccact
     1321 ttctttccgc ggatgagctg caagtcggcg tccttgtcgt aataaatctt catacgtcac
     1381 tcctgaatgt tcatagggca catggatgga aacaatcgtg cacagagagg atgcgcgcgt
     1441 tattctcgag cgagcttctt cggttggctg agggccgggc ggatcgcctc acgcgcgatc
     1501 gctactcgcc ccgtccggat cagctccttg atgccgagcg gctggagcaa gttgatgatc
     1561 gcctcaagct ttttcggatc gcccgtgacc tcaatggtat aggtcgatgg tgtggaatca
     1621 atcacattgg cgcggaaaat gtccgcaatc cgaagcgcct cggcccggtc ttccgccttg
     1681 gtatggactt taatcaacgc cgtctcgcgc gaaacgaact cgctttcatt gaggtccacg
     1741 accttgatga cgtcgatcag cttgttgagc tgcttcacga tttgctcaac gattcgctca
     1801 tcccctgacg tgacgatggt catctgcgac atggacggat cgagggtcgg agcgaccgac
     1861 agactttcga tattgaatcc gcggccgctg aacaatccgg ccacgcgtga taacacgcca
     1921 aacttatttt caacggtgac tgaaatgata tgttccatca ctatgctcta tggtgctagc
     1981 tgtcaggctg acagcgtgtt ttacgcggtt aaaatggtgt ctttgttttc atccgatccg
     2041 gtactgggca caccggccat tcgctgtttc aactcaggcg ggtccgcaag aatcatctcg
     2101 tgattgcagc cgcccgccgg gatcatcgga taacaattct catagggata ggtgggcaca
     2161 tccacgacca ctggcctgtc ggtcgagatg gcctccttca gcaccgcatc gaggtctccc
     2221 accttaccgg cgcgtagtcc gactgcgcca taggcttccg ccaatttcac aaaatccggc
     2281 gtggtgtcca agtagctgga ggcataccgc ccttcgtaga acaggtcctg ccactggcga
     2341 accatgccgt ggaaacgatt attcagaatg atgattttga ccggcagctt cgacaccacc
     2401 gcggtggcca tttcctgcat attcatctga atgctgccgt ctcctgccac acaaagcacc
     2461 aatcgatccc tgaaggcagc ttgggccccc atggcggcag gaaagccgaa tcccatcgtg
     2521 cccaatccac ccgaggtcaa ccagcgattc ggccgggcca gtttgaaata ctgcgccgtc
     2581 cacatctgat gttgccccac gtccgtcgcc acgatcggat cacgatcctt cgtcagttca
     2641 tacaaccgct tgacgacatg ctgcggcttg atcgccccgt ccggctcttg ttgataggcc
     2701 agcggatgcg cctgctgcca ttcacggatt tggtcccacc agggcttgcg aagatctttc
     2761 tgattgccgt tgaccgtggc gcggagaatt tggttcaact cccgcagcac cgccttgcaa
     2821 tcacccacga tcgggatatc gacatgaatg ttcttacgga tcgaggttgg atcgatatcg
     2881 atatggatca ccttggcgaa cggacaaaac tccgacacct tcccggtgac ccggtcatca
     2941 aagcgcgcac ccacggcgat caccagatcc gaataatgga ccgccatgtt ggcgcagtag
     3001 gtcccgtgca tgcccaacat gcccatcgat tggggatgct cgccgggaaa cgcgccgagg
     3061 cccattaagg tcatatcgac agggatctgg gtcatctctg ccaattcaag caactctttc
     3121 gacgcctgcg aaaatacgac tccgccgccg acatacagaa tcggcttctt cgccttcatg
     3181 atcgcttcag cggcctgctt gatctgccat ttattgcctt cgtaggtcgg attgtatccg
     3241 cgaatggaga cagagctcgg ataggtgaaa tcggccttgg ccatggacac atctttggga
     3301 atatccacca gcaccggtcc cgggcgcccg gttgtcgcaa tgtagaacgc ttccttaatg
     3361 gtggtcgcca gatcgttcac atccttcacc aggaagttgt acttggtgca gggacgactc
     3421 aggccgatgt tgtccgcttc ctgaaatgca tcattgccga tcaagctcgt ggacacttgt
     3481 ccgctgatac acaccagcgg gactgaatcc atataggcat cggccaatgc ggtaatcaca
     3541 ttggtcatac cgggacccga cgttactaaa cagacgccgg cctttccggt ggccttggca
     3601 tacccttcag ccatatgccc ggcaccctgt tcgtggcggg tcaatacgac ttcaatatct
     3661 ttctgctggt gcagcatgtc gaaaatcttc aacacgacgc cgcccggcaa ggcgaaaatc
     3721 gttttcacgc cttcagcttt taagcattcg atcaggattt cggaccctgt gagcttcata
     3781 tcaccctccc cttcgcgcat cattagcgaa ggacgtgtgc cgtcactgga aacagcagca
     3841 acctgcgtca cgtttgtgtc acagactgct acgatctttc tgaaaaatca atgggtaaga
     3901 tggcggatcg tatcaccagc tcgcaagtga ggtcaagaga gtcacgacag gaactcgttg
     3961 tgcgacagac tagtgtcgat caccgccccg tggtatagga acgttctcgt gttgtgagcc
     4021 tagtgccaat gagtcccatg cgcctcacga tcatgtcccg tcgcgaatgt cacttgtgcc
     4081 atgtggtggc ccgagtggca gcccaggtgc aggaggatct cgcgttccat ctgaccatcg
     4141 ttgatatcga taccgatgaa cagctccggc ggcaatacgg agaccgcatc cccgtggtgc
     4201 tattggatga ccgcgaactt ctgtccggca aggtcactgc gggagatcta cggaaggcga
     4261 taaaaaaagc gcgttggaga gaccctataa gccggattct gtcccgtata aagcttgcgc
     4321 ttacacgggg gtgatcattt ctctgggact cgagttgccc cgagcctcaa gcaacctacc
     4381 cggagacttc ggccgggcca gcctttccgc tgagctcttg cgagcccgcg ggcgtccccc
     4441 tatttggtct tgctccggac gacgcttacc gtgccgttga tgtcgccatc accgcggtgg
     4501 gctcttaccc cgccgtttca cccttacctg agccgccggg agtgaccgaa gtccctcacg
     4561 cggccatcgg cggtttgttt tctgtggtgc tggtgtcgga tcgctccgcc tggacgttat
     4621 ccagcgtcct tgcccttgga gtccggactt tcctcccgcc gagcaggctc ggcgagcgag
     4681 cacccgtgtc cccccagcgc gcggaggaaa gtatacgagt ccccccaggc cgattcaagt
     4741 aagaagccgg gcggacttaa tgcaatgcgg gcaactcgtg gttgggtgca ggcggcttcg
     4801 actgatagat gggcatggcc tccgccatcc actcctccag ctgttgaatt cgggtttcgt
     4861 ggctcgggtg ggtggacata aattcggacg gagatttacc tccggacatc tcgcccattc
     4921 tttgccacaa ctggatcgcc tcacgcgggt catagccggc atccgccgcc agcaacacac
     4981 cgacatagtc tgcctctgat tcgtgcttgc gactgaaggg cagcaacacc ccgacctgcg
     5041 caccgacacc caatgccgcc atgcctgcct gcgagagcac cggattggcg ccactcaccc
     5101 ccagcgcgat gccgatcgct tgtaaggtgg tttgtgccaa tgtgttctga ctcatccgtt
     5161 ctccgccgtg acgagccaac gcatggacga cttcatgccc catcaccgcc gcaagtccgg
     5221 cctcggtctt ggctacgggg aaaattccgg tatacaccgc gattttcccg cccggcaggg
     5281 caaaggcgtt catggtctta tcgtccttga tgaccgtcac ttcccattca aattcattgg
     5341 ccacgtcgct gtatttggat cgtttagcgg cctcgatcac tctcgcggcg acacgtttga
     5401 ccggctcgat ctcccgaggg tcggtggagg gcctcatttt gggatcgctc ttgacgtcgg
     5461 catacgcctg cgcgcccatc tgcacttcct gggacatcgg catcatcatc agctgccagc
     5521 gtccggtgta gggattggtt tggcaaccag tcgtcaccaa catggtcacg atgccgaaac
     5581 acagccacag caggttcgat ggccgggcag atttcgacca cccctcacgg ttcgatttca
     5641 tcttcatcac aggcctccgc aaattgacca gtctgatatg ctctgctaga ttaccgcgcc
     5701 gccccacccg tttctactgg gagtttcacc gagtgcctat caccacgaca ctcttctcgc
     5761 tgaatcgaat tggcatcgac gaatccggca aaggcgatta ttttggacct ctggtgattg
     5821 ccgccgtgtt cgtcacgcct gcatcagaac aggatctcgc cctcatgcag gttcgtgaca
     5881 gcaagaagat ttccgatggg cgtattctcg aaatggcccc cgacatccgg acagtgtgcc
     5941 cccacagcat cgtggcgatc ggcccgcagc gctacaatga gctctatgcc aagatcaaca
     6001 acctcaatcg cctcttggcc tggggccatg cacgggcgct ggaaaacctg cttcagcaag
     6061 tcgactgcga tctggcgatt gccgaccagt tcggcgacga acgattgata ctcaacgcgc
     6121 ttcaggagaa aggcaagcag atccggttgg tgcaacgcac gaaagcagaa acggacttgg
     6181 ccgtagcggc cgcatcaata cttgcgcgcg ccgaattttt attgcgcctc caacggctct
     6241 cgcaggaatt acacacgacc ctacccaagg gtgcatcccc tgccgtggaa ttggccggac
     6301 gtatggtcgt gaaaaagtac gggcgggaca gactgagtac cgtcgcgaaa ttgcacttta
     6361 aaacaacaca gcaggtgctg aacgacacct agacggattc gccgagctca aaatccttcg
     6421 cctggtcttg gacgagaggg cgctttccct ctggaacagg ctcaccttcc caatacaaca
     6481 ttcgataaca ataggggcaa gtatagacgt cgtccccgcg tttgacctga gaaatcaatt
     6541 gaggcggcac ctggagccgg cacccgatac aaataccatc cttgatcagc gccagcgcct
     6601 ggtcttttcg cgtggctttc agcttgttat accgagcgag caggcccttc tcgacccgtc
     6661 ctgacaattc cttttgttga gcttccaact cggcgagttc cgcagcgagc acgcggtcct
     6721 tctcgtcgag caccgctttc tctttgctga aaagggcttc tgagtctttc agttgcacct
     6781 gggcggaagc aatcatccgt tgagtctgtt caatctgctc catcgcgagc aggatcttct
     6841 cttcgatctc tccgcgtttc ttattggcca gctcgacttc gaacagatgg gcctgatatt
     6901 cctggttcgt cttcaactgg gcggcgcgat ctttcatctt cccgatgcgg tcctcgtgcg
     6961 cctccaggtc cttctcgtga cttcgccgtt ccttgttcaa ggtctcgatc gaagccgacg
     7021 cgtcttgaac cgtccgcctt gcttcccgca gaggagcctc attcacttca agccgttcgg
     7081 gtattcttcg ccgttgttct ttgaggtcgg cgatgcggag atcgagtttc tgcaattcga
     7141 tgagagggga aagctgtggg ttcaacgggc tccttgtgag ttgcgcgaga gcaacgtcgg
     7201 cacgacgcct ctcgcaccgg aatgatggtg aggcgctcag gctggtgggc ccactaggac
     7261 ttgaacctag gaccagctga ttatgagtca gccgctctaa ccacctgagc tatgggccca
     7321 gccctgccgc cagtgacctg gccgcagcct gcatcacggc atacctggtt cgagcggcct
     7381 gattctaaag ctgccagtcg gaaagagtca aaccactcct gacgacgaag actagagact
     7441 ctccacgaaa ctacgcagct tcttgctacg gctcggatgc cggagcttcc gcaacgcttt
     7501 cgcctcgatt tgccgaatgc gctcgcgagt cacctcaaaa tcctgtccga cttcttcaag
     7561 cgtgtgatcg gtcgcttcgc cgatgccaaa gcgtttccgc aacacctttt cttcccgagg
     7621 agtgagggtt tccagtgcgc cattgatctg acgttgcaag tcgtaccgaa tggcggcttc
     7681 caatggcgag accgctttct tgtcttcgat gaagtctcct aagtggctgt cttcctcttc
     7741 gccgatcggg gtttcgagag aaattggctc acgggcgatt ttcagaatct tgcgcacctt
     7801 gtcgagcggc aaatccatgc gttcggcaat ttcttccggc gtcggttcgc gaccgagttt
     7861 ctgcaccaga tggcgcgagg tcctgatcag tttattgatc gtttcgatca tgtgaaccgg
     7921 aatacggatg gttcgcgcct ggtcggcgat cgcacgggtg atggcttgcc gaatccacca
     7981 ggttgcgtag gtactgaact tatacccacg tttgtattca aacttatcga ccgccttcat
     8041 gaggccgata ttgccttcct gaatcagatc caggaactgc agcccacggt tcgtatactt
     8101 tttcgcgata ctcaccacca gacgcagatt ggcctcgacc aattccgcct tcccgcgttt
     8161 aaccttttcc tccgccacat cgagatgctt gacggcatcc ttgatctctt cagcggaaat
     8221 cagcgcttct tcctcttcaa gttggcggat ccggcccttg gcggcttgat agtgtttttt
     8281 gatgtcctga aggacttctt cggagagccc ggtcctgcgc ttcaccgcga gcacatcttt
     8341 atgggttcga cacaacttcc gcagcaattc ggcgccggcc tcgccgccga caccgagacg
     8401 acgctggcag ctcgtgactt cccgctccga ttgacggaac agcaggttaa ggtcgcgtac
     8461 ccgctgggtc atgcggtctt tcagaacgcc atgcagattg accgactcca tcttatccac
     8521 aacctggcca cgcaccgtgt cgatctgctt gcgcagcttc ttttgttttt cgggatcggc
     8581 accgacatga cgagccttgt cgtagagatc cttgagcgag gcagatacct tgcgcacggc
     8641 gttcaaagaa tccagcgttt tcacccggag ctcttcgtaa tccttttcga cggcttcttc
     8701 ttcgaagtcc tcttctgtct ccacaaccgg cacgatctcg cgcacatcaa tcttgccgtt
     8761 tttcagctga tcgcggagat tcaggacgaa ctccagggtc atcggcagtc cgtatacgac
     8821 cgtggcaata tctttcttgc cttcttcgat tcgcttggca atctcgattt cgccctcgcg
     8881 gctcagcaga gccacactgc ccatttcttt caggtagagc cggacagggt cgtcggtgcg
     8941 gctgagcgcc cccggggtga gatcgatctc cttttcgttt tcttccgagg agtcggattc
     9001 ttcgctctcc tcaatcgctt cctcgccttc ggcggccttt ggagcgcgct ccgtctcagc
     9061 ggactccaca atctcgatgt ccatttcgcc gaacatggtc atgatcgtgc tgaattggtc
     9121 cgacgagacg acatccgccg gcaaggtgct gttgagatcg tcgtacgtga ggaagccctt
     9181 ctccttgccg agattgataa gcttcttcac ctcgccgagt aattcttgtt tcggcatacc
     9241 ctactccttc accgcagacg tcagcgcaac cggcatcaca ccggctttcc gaatccgcat
     9301 atcgttaatc aatccgttca ggcgatgcac ttcatcttcc cgtcgttcgc gttccgcgac
     9361 cttcaattct tgaatcaaga ggcccatagt ccgttcgcgg cctcgccgct ccagggtctc
     9421 caaacacccg gcaatatggg ccggcacgtc gtcataatgc tgctcctgca tcgacagctc
     9481 cgacaccaac gagccgcaga cctcatccgt gatcaatgca tccagcaggg tcctgacgga
     9541 caccctgcca tcgtctgcca gatgctgcaa ggcacattcg atcaaccgct tgtacgccgg
     9601 tgccgaaaac gcatcggggg acagtttccg aagatccgcg gcagataaac tcccctgcac
     9661 aagcaaatgc gcgagatcgc gctcttcagg attgggcttc actctggacg ggactgagat
     9721 ggagggagcc ttggctgtcc ggtccgggcg acgctgctct tccgagacga gcgtgggata
     9781 gcgatcgatg aggcgctgct gactgagtcc caatcgttct gcaacgagcc tgatccgctc
     9841 ttcgcgctcg atcggatgcg cacttttctg aagaatccgc aacaccgcat ccacagcccg
     9901 aatccggtct tccacgctgc ccgactccgc cgtgcggagg ctgtgctcaa tggcaaaatc
     9961 caacaggctt ggcgccgcgc ggtgcaaggc cgcaaaccct tcggcgccat gttgccggac
    10021 atacgtatcc ggatcgtcac cctcaggaag cgagacgacc ttgacgctca agccgctatt
    10081 gacgaacaaa tccagcgagc gcaatgccgc ccgaacccct gcctgatcgg gatcgaagag
    10141 caacacgata ttcgacgcga accggcgaat gaccgtaatg tgctcagcgg ttaaggctgt
    10201 tcccaaggtc gccgccacat ggcgaatgcc cgcctgatgc aacgcaatgg catcaaaata
    10261 gccttcgaca atgatcaacg tatgctgctg gcctgcggcc tcacgagctg cgtccaacgc
    10321 gaatagcgtc tggccttttt tgaataacgg ggtttcaggg gagttcaaat acttgggcat
    10381 cccgtcaccg agaatacgac cgccgaatgc cacaacccgc ttccgcaaat ccgtaatggg
    10441 aaacatgatc cgggaacgga accggtcgta atgccctgag acggcagttt tctgtgagcc
    10501 gctctgatca cgtggaatag aaaggccggc tgcgacgaga tccgccggcg caaatccctc
    10561 tttgagcatg gctctagtca gcccgtccca ttccggtgga gcgtaaccga tgttgaattg
    10621 cgcggtggtg tgctgctgaa tgcctcggct gtcgagatag gcacgcgcct gagcgccggt
    10681 aggcccttgc gtcaacatac ggtgatacca ggcccccgca gccgcattga ggcgttccaa
    10741 tcggccgagt tgcgtgcgcg cctcattgga aactccgccg gttgattcag gaacatccac
    10801 ccccactttg cgccccaaat cccgaacgat ttcagggaag gccgctccgg ttaatctcat
    10861 caaaaacgta tacacattgc cgccggcccc gcagccgaaa cagtggaaaa tctgccgcga
    10921 tgagctgaca gtgaaggaag gagatttctc ttggtgaaag ggacacagac ctttgaggtt
    10981 ctgcccggcc cgcgtcaacg ccacatgttg gcccacgatt tctgcgatgt ccactcggtc
    11041 tctgatttgg ttgatgacgt cgtccgaaat caggccttgg cccacggcgg tcctcgctag
    11101 tgcccgcagg gatcctaccg gtgaatgtac cggctggatg cctttgacgc gattgaaagt
    11161 tgaccgttca acctaacaaa cggtccgcat atgtgtcaat caaggagcag tgcccattat
    11221 cccggaggcc aggccatatg ccttccgccg aggacatgca ggtggagatg aaacaccgtt
    11281 tgtccgctgt ccgctccggt gttcgtgaca atgcggtagc cagactcagc caggttcttc
    11341 attgctgcaa ccttggagca ggtcatcagc aaatgcccca ataacgcctg atcaccgtcc
    11401 tgacaattct ggactgccgc cagatgacgt ttcgggatga ccaggatatg gacgggagct
    11461 tgggcattga cgtcctcgaa tgccaacaca cgatcatcct cgtggacgat ttttgccgga
    11521 atggcccggt tcacgatacg acagaagatg cagttatcca cgcgactccc cttccggtgc
    11581 ctgacgaatc ccggacttgc cgaacctggc tccgagctct cgatacactt cgctcagcgt
    11641 cacatcatgg taaccgagaa ccaggagggt gtgaaaaaac agatcggccg tctcgtaaat
    11701 aatctcgtcc cgtttctggt ttttcgcggc aatgatgacc tcgcccgcct cttcagccac
    11761 ctttttaagg atgcgatcca cattgccttg cagcagcttg gacacatacg agtccggctg
    11821 cggagcggcc ttccgtgcca gaatcgtctg atagagccgt tcgagaatcc ctccgccggc
    11881 atcctgcgtc ttgcctggtt cggcccgtcc atctgcactc attctcgaaa aaaagcaggc
    11941 gcgttcgccc gtatgacagg tcggcccgac cggctccgct ttgacgagaa tggtatcccg
    12001 gtcacaatcg acgaacagat ctttcacccg caaaaaatgt cctgacgtct cacctttttc
    12061 ccacaatttc tgacgcgagc ggctccaaaa atgaactgat ttggtcgcca gcgtcttcgt
    12121 gagggcttcc tgattcatgt agcccaccat gagcacggtg ccatcgaacc agtcttgaat
    12181 cacggcgggg attaaccctt gcccgtcaaa cgtcatactg cggctgtcgc tcgacattac
    12241 ctgctccatt taggcggcgc ctattcgaac tggaacgcca cggtcccgca aaaaggcctt
    12301 ggcctgctga atagtatggg tccggtagtg aaaaatcgac gcagcgagca ccgcctcggc
    12361 cttccctttg accaacccgt catagagatg ctccaacgtg cctacccctc ccgaggcaat
    12421 gaccgggata gagagactct ccgacacagc ggccgtcagt gccagatcat atccgttttg
    12481 ccggccatcc tggtccatgc tggtcaacag gatttctcca gctccatact ctgccatgcg
    12541 ctgagcccat tcgaccgcat caagcccggt cgcgtttcgt ccgccatgag tatacacctg
    12601 ccagcggcct gcggcctccg ctcgcttggc atcgatggcc accacaatac attgcgtgcc
    12661 gaaacgctga gccgcctcac gaacaaattc aggcttttga accgcggtcg tattgatact
    12721 gaccttatcc gccccggcat tcagtaatgt gcggatatca tccagggtgc gcacgccgcc
    12781 cccgaccgtc agtggcataa acactcgggc ggccgttcgt tccaccacat cgacgatcgt
    12841 ctttcgattt tcgtgtgaag ccgtgatatc caggaagcac agctcatcgg cgccttcacg
    12901 atcatagatg gtggcgacct cgaccggatc gcccgcatcg cgcaaattga cgaagctgac
    12961 gcccttgacg actcgaccgt ccttcacgtc caaacaggga atgatacgtt tggtcaacat
    13021 aggaattcgc gacgcctgaa acgtgaaacc tgaaacgaaa cggttctact cctgcccgcc
    13081 aaacgagacc tcaacgattt ccgagagcgg cgagggcagc tcgataatcc aacttgccgt
    13141 catacaaagc tttgccgaca atcgcgcctt ccacacgagg gccgagcgcg cggaccgctt
    13201 gcagatcctc cacccgcgtg atgccgccgg aggcaataac gggaaaagcc gcacagttga
    13261 cgacctcccc taacgccgca aggttcggcc cattcaacat accgtcgcgc gcaatgtcgg
    13321 tatagatcac cgcacccagc tcatggtcgg ccagttcacg gaggagatca atcgctttgg
    13381 tttcggaaac cgcagtccat cccttcacgg cgaccttgcc gtctcgcgca tcaaggccca
    13441 gcaggatacg ccggggaaat tctcgacagg cttgcgccag gaaggcccga tccgtcaggg
    13501 cagccgtccc aaggacgacc cgcgcgactc ctgcctggag atatttccgc accgtgtcga
    13561 tcgttcggat accgccccca acctgcacct ttacgttgac ggccttcatc gctgactcaa
    13621 tctgaggaag gttctttggt tccccatcaa cagcgccgtt gaggtcgacg atatggatga
    13681 gatcggcccc ctgttcctgc caacgttttg cgactgacgg cacatcctcc gaatacacgg
    13741 tttcggccgc catatcaccc tgccgcagtc gcacacagcg gccatctttc agatcgatcg
    13801 ccggaattac acgcatatcc gcacctgctt cctcacggtt acttcccttc acccgctgct
    13861 gcgccgaacg gaaacgcctc cgctaattcg gtcgccccat aggccgctaa ctcttccgcg
    13921 gtcacgaagg tcccatagcg ctgaacaaac ccaagcacat cttccgtcat cggccgctgc
    13981 ttttcgtagt agttgccttc ccataggacc atgccatcag gggccacgag tttcacttca
    14041 aaccccacgg cagcgggagg gtcggcaccc aatcggctgc cgacacgttc ttgatagacc
    14101 aacactttcc cgctgagcgc ggcatcggcc ttgagacgct gcgcaatttt gtgagccgga
    14161 atggtctcca cagagccgct tcctctcgaa agatcccgag ccgcgcccat cgcttcctga
    14221 ggggaaatga cctggagacc cggcttgccc ttcaatttgg cccacatcag atctgtaatt
    14281 ttttcgcccg caccgggcgg caccaaattt gttcgccgaa ccgcctgatc ggtcgtgggc
    14341 ggaaccccca ccgccatgtc agaacgtcgg actcccgacg gcacagggaa ggatggcccg
    14401 cttgtttcga tggcctgagg cgtcgccatt gtttcaaagg gaatcagcac gatgttgcga
    14461 acctgatact ttccagcttg aggagaggcc ttggaggtga ccttggttcc gctgcaccct
    14521 gtggtcagca ctacggagag cagaatgaac agcgttcgcg ggatgcaggt actcacgtcc
    14581 aggccccgaa attcttaatc acctgaagac cgacggcctg actcttctca ggatggaact
    14641 ggcaggcgac gacattgtct ttccacaccg cggatgcgaa tggcgctcca tagtcagtca
    14701 cggtggcaac gaccgcggaa tcggcaggct caacataata ggagtgcacg aagtaacagt
    14761 aactgcccgg tgcaatcccg gcaaatattg gcgcaggccg catgatccgg atatcgttcc
    14821 agcccatatg cggcaccttt aacgaagcat ccagcacaaa cctcttcaca cggccgggaa
    14881 tgattcccag gcccttgtgt gttccgaatt cttcactttc cgcgaagagt agttgtaaac
    14941 cgaggcagat acccaaaaac ggtttgccgg attgaatcgc ggcatggatc ggcccgatca
    15001 actcatatcg ctccaggttc gccatgcaat ctccgaatgc ccccacgccg ggcaacacca
    15061 catggctggc atccgcaatg acgcgagcct cgcgcgtaac cacagcctga tgtcccacgg
    15121 cctcaaaggc tttcgagaca ctgcgcaggt tccccatacc gtaatcaatg atggcgatca
    15181 tgttgctttc gcggacgatg cgtaatggca gctaccactg cccccgtctc acaccccgga
    15241 tctgactaga ggcttccctt cgtcgagaga accgctcctg acagccgctc ttcgggcaac
    15301 gtggcttggt ccagcgcccg cgccaacgcc ttgaagatgg cttccatgat gtggtgagga
    15361 ttgcgaccat attgcaggtt tatgtgcaga ttcaggccgc catgggtgac gaaggcctgg
    15421 aaaaaatcct cgaacagccc caggtcgaac gttttgatct tccggtccgg caaattgacg
    15481 ttatagacca gatagggccg accgctgaga tccaccgtca cctgcgcaag cgtctcgtcc
    15541 agtggcactg acgcccatcc gaatcgcttg atccccgcct tttcgcctag cgcttgatgc
    15601 agcgccttgc ccatgacaat gcccacatcc tccaccgtat gatgctcgtc gatgtcgatg
    15661 tcacctttgg cctgcacggt gagatcgaaa aacccatgtt tggctagcag atccaacatg
    15721 tgatcaaaaa accgaatgga cgtgtcgatc ttcccctggc ctgtaccgtc caaggtccat
    15781 tcgacacgaa tatcggtttc ctttgtcgcg cgatgcaacg aggcctgtct gggaactccg
    15841 gtgtttttca tgaaaacctg ctttgagctg atttggcatg cgcatcgaag ccttcgatat
    15901 gcgccagtct gacgatatgg tccttggctt tcgtcaattc ttccctggtg taatggacga
    15961 tgttactgac cttcacatag tcgttgacgg acaacggcga aaagaaccgg gcagtggcgc
    16021 ccgtcggcag cacgtggttc ggcccggcca cgtaatcggc cacggcaggc ggcgtataac
    16081 gacccagaaa gagcgccccg gcatggcgaa tctgctccag ataatcaaac ggacgatcga
    16141 ccgataaggt cagatgttcg ggcgcgatat cgttcgccac ctcgatggcc tcatccatgg
    16201 aaggaacgac gaacgcgaca aaatgtcgtg cgatcgattt ggccgcgatt ttctcccgct
    16261 gcaagccctt caactggacc tgaatgagcc gtacaacctc ttttgccagc gatgcggagg
    16321 tggtcaccag gtagacctgc gcgtcttcgt catgttccgc ttcacacaac agatcggctg
    16381 cgacatgcgc cggcttcgca tcgtcgtccg ccaccaccaa tagctcgctg ggaccggcca
    16441 ccatatcgat tccgacggtg ccatagagca atcgcttcgc cgtcgcgaca tacatgttgc
    16501 ccggcccaac aatcttatcc actttggcaa tgctcttcgt cccaaaggcc atcgcgccga
    16561 tggcctgcac tccgccgacc cgatagattt catccacccc ggcgatatca gccgcgacga
    16621 gcaaataggg gttgatctcg cccttcggcg tgggtgtgca catgacgatg cgtcggactc
    16681 cggccacctt cgcaggaatc gcgcacatca gaaccgagga cggatagacg gctttgcctc
    16741 ccggcacata cacaccgacg gcatcaagcg acgtcaccat ctggccgagc gtggcattct
    16801 cctcctggta catccaggtt ttggtgcgct gccgttcgtg aaactgccgc acccgctcag
    16861 cggcataccg gagcgaatcg ccctcatctt tgcgaatgtg ataataggct tccttgatct
    16921 cctccggtgt cacacggatc tgatcaagcg tgaccgacac ccgatcgaac ttcttggtat
    16981 accgcagcac cgcgcggtct ccgcctttct ccaccgcctg aaggatcgcg cgcacgcttt
    17041 tctcgacagt ggccgcttgc gaacgagagc gggctgtgat ttttcgtaag gctttggcga
    17101 aggctcgatc ggtactctcg agaatagtca tgacatccgt cctgccgctg cgccgccagt
    17161 atcgggcgcc gcatcatggg aacccacgac tgcccgcgtg ggataggtcg gccgcgctac
    17221 tccgcagcca cggctgtgcg cagccgatcg atcaacacct gcaacggttc atgtttcaat
    17281 ttgaggctgg cccgattgac gatcaatcgg gcggtggagt gggtaatcac ctctacctcc
    17341 gccagatcat gggcctttaa cgtactgccc gtctcaacca gatcgacaat gcgatcggcc
    17401 aatccaacaa tcggggcaag ctcgatcgac ccatacagtt tgacgatctc aaccggcatt
    17461 ccgcgctgat tgaagtagcg ctcggtgacg ttggggtact ttgtggccac ccggaccttc
    17521 gaggaccacc gatccggtga tggctgtccc tgcaacgcgg cgaccgagat tctacacgct
    17581 cccaccttta aatccaacgg ctcgtagaca tcgctgccct gctccagcaa gacatctttc
    17641 cctaccacac ccacatccgc ggccccatgt tcgacatagg tcgggacatc ggtcggccgc
    17701 acgatcagaa aggtggcatt gttggcggca cagtcaaata ccaacttccg gctttccaca
    17761 gacaaccctg ggctgtaata accggccgcc ttcatgagat ggagaaccgg cccgagcaat
    17821 ttccctttcg acagcgcgat cgtgagtcct ttcggctttt cgtcttgcga tttcctcgcc
    17881 ttcacgttca ctttcccttt ctccgctcga tgctggcccc caagatccgg agcttttctt
    17941 ccaaccgttc atagccacga tcgaggtgat acacacgcga cacctcggtg gtaccttccg
    18001 ccgcgagacc agcgacgatg aggcccgcgc tggcgcgaag atcggaagcc atcaccggcg
    18061 cgcctgtcaa acgttccttg cccgtaatca ccactcgatt gccttcgaca cgaatatccg
    18121 ctcccatacg gcgcagctct tccacatgca tgaaccggct ctcgaaaatg gtttccgtaa
    18181 ccacgctggt tccttcggcc accgccatga gggccacaaa ctgggcctgc atatcggtgg
    18241 ggaatccggg atgtggactc gttcgcacat tcgtcccttt caatcgcccc gtgaccttga
    18301 gatgaacgcg ttccttttcc tcaatcaact cggcgccgct ttcccgcagt ttcatcaata
    18361 agggttccat gtgctcggga cggcaccgat cgacgatcac ctcaccaccg gtaatcgctc
    18421 cagccaccag ataggtcccg gcttcaatgc ggtcgggaat gacttcatga tcggcgccat
    18481 gcaattcggt cacgccctca atcgtaatca tatctgtgcc tgcaccggcg atgcgcgcac
    18541 cgcgcttgac gaggaatgcc gccagatcgc tgatttcagg ctctttcgca gcattttcca
    18601 gtaccgtggt gccctctgcc aacacggccg ccatcatgag attctcggtc ccggtgacgc
    18661 tcggcgtatc aaagtaaatg cgactgcccc gcaagcgacg cgcgctggcc ttgatatacc
    18721 catgttcgat ttcaactgcg gcgcccattt tttccaaacc agccaagtga aagttcaccg
    18781 gtcgagagcc gattgcgcac ccgccgggaa gggaaacctt ggcctccccc aatcgagcca
    18841 cgagcggacc taagaccagc accgatgccc gcatggtgcg gaccaaatcg tagggcgctt
    18901 ccgtcgatgc aatggcttcg gcctgcacaa ccgtctgatc gccctcctga gagacggcaa
    18961 tgcccagcat gcgcagcaac ttgcccatgg tcaacacatc cactactcgt ggcatgttcg
    19021 acagcacaca ttcgccccca cccagaatgg tggaagcaag aatcggcaat gccgcgtttt
    19081 ttgccccgct ggtgcggacc tcgccttgga gtcgacgtcc gccttgaata agaatctgat
    19141 ccatcagtct cagggaatca ttggtgcatc atcgatggct atggaggtca ggacgatgaa
    19201 gatgataagg actcttcttt tttctcgaaa cagacgaccc gttcaatgcc gccctgatcc
    19261 cgcaacacca cataggtacg aagccgacca ccttcttcag catgacggca gacagctgct
    19321 gcctggccga ttcccacttc cataagcagg gccccacctg gcttcaaata cgccggcgcc
    19381 tgtgcaatca agcggcgatg cacatccatg ccgtcacgac ctcctgccag cgccaaccgc
    19441 ggctcgaaat ctcttacctc cggctgaagg gtctcgacat ccccgtccgg gatataggga
    19501 gggttggaca ggatgacttc aacctgattg ggcaaccctt cctgaccgat cggatccagc
    19561 aagtccccct ggaggcaagt aatacgtgcc tcaaccccgt accgtgccat gttgtttcgt
    19621 gcgaccacta aggcatcggt cgaggcgtcg atggctaata cgcgcgccgt cggcaaagcc
    19681 gaggccacgg atacggccaa acaccctgat ccggtcccca catctacgat ggtcgcgtct
    19741 gatatctgca cgcaccgacg gactgcttcc tccaccaaca atacgctctc aggacgggga
    19801 atgaggaccg agggggtgac gaaaaaatcc cgtccgcaaa actcttgcgt accaagcaca
    19861 tactgcagcg gctcacgatt ggctcgccgt tcgaccaaca cctgcactcc ctcacattct
    19921 tcaggcgtta aaccgcgctc tgtattgatt cgctgcatga gtggcgagag tttcaaaaca
    19981 tgctccacca accaggcgga ttccaaggcg ggctggtcga tgcctgcggc atccaggcga
    20041 gattccgact ttctcagtaa ctcgccgaga ctcgatacgg aacaggcggc gtctgccaac
    20101 tgctgctgcc tcattttgtt tccagactgg ccaaatgttc gtaatgcgct ctcaacgcct
    20161 gcacaatttc ctccagatcg cccgccaaca cctgatcaag cttatgaacg gttagtccaa
    20221 cgcggtggtc ggtcacacgg ttttggggga aattgtacgt gcggattttc tcgctccggt
    20281 caccggtccc aacctgcgac ttacggtctt gggcaatagc cgcctcctgc ttttcccgct
    20341 ctgcctccac aatccgcgcc cgcaaggttc gcatggcttt ggttcgattt ttcagttgtg
    20401 accgctcatc ctgacagctg acgacgacgc cagtgggaat gtgcgtgatg cgaacggccg
    20461 agtacgtcgt attgacgctc tgtccaccag cacccgagga acaaaatgta tcgatacgca
    20521 gatctttggg atcaatgtgg acatccactt cgtccacctc cggcatcacc gccaccgtaa
    20581 ccgtagaggt gtgtattctt ccactggctt ctgtagtagg gacgcgctgc acgcggtgca
    20641 ctccgctctc ataccgcaga cggccgtaag ctccctttcc ctctagcaga gcgatcactt
    20701 cacggtagcc gccgatgccc gtctcagagg catcgaccac ctccagccga aggcgattcc
    20761 gctctgcata cttgagatac atgcgaaaga gatctcccgc aaataaggcg gcctcgtctc
    20821 cccccgtgcc agcccggatc tcgagaaaca cattcttctc atcgcgggga tctttcggag
    20881 taaggaagtc cttcgcgcga gcctcgatgt ccaagagctg ttgagtcaaa tgctcgctct
    20941 cttctgcaaa gagctgcttc atgtcagccc cggtgccgga atcctgcagc atcaccgtca
    21001 cttcgtggag ttgcttctgg gcttgggaat aggcggcaaa ctcctgagca ggctcctcta
    21061 actccgttcg ctctttattg agcttgtgaa tcatgcccgg ctgattgagg accgtcgggt
    21121 ccatgagctg attcgtcagc tcctggaacc gcgcagccat cgcttcccat tttttgatca
    21181 gcccatcttc catgtctcgc ccattccggc catagccctg aagcccaaaa aacaagagac
    21241 cctgccccaa aaggaagcag ggtctccatg atgtcctgac tgaggcctac ttgtcttttt
    21301 tggcgtactt ctttttaaac cgttcgacac gcccttccgt atcgacgatc ttctgggttc
    21361 cggtaaagaa cggatggcac cctgcgcaaa tgtcgacctt aatgtcacca atagtggatc
    21421 gggtcttgaa cgtgttcccg caagcacagt gcactgtcgc ttcacggtag actggatgaa
    21481 ttcccttttg catacctgct cctctactga cctagaatca ttgactcgtc ctgctcgcca
    21541 gggtgcacga ctttacactg gagtggccta cactggcaag cggtgcctac cgattcattg
    21601 attgcaaaaa ttcctgattc gttttggtcc caccgatctt gtccatgagg aactccatgg
    21661 cttccatggt gcccaacggg ctcaagacct tgcgcagaat ccacatcttg tttaagcggt
    21721 cacggtcaac cagcaactct tccttacgag tgccagactg actgatatcg atggcaggga
    21781 agagccgctt gtccgccagg cgccgatcca ggtgcacttc catattgccg gtacccttga
    21841 attcttcgaa gatcacatca tccatgcgac taccggtgtc gatcagcgca gtggccatga
    21901 tggtcagact gccgccattt tcaatgttcc gagctgcacc gaaaaaccgc ttcggccgct
    21961 ggagagcatt agagtcaaga ccgcccgaga ggaccttccc gctgggaggg gcaatcgtgt
    22021 tgtaggccct agccaaccga gtgatgctat cgagcagaat gaccacgtct tttttgtgct
    22081 caaccagacg cttcgctttt tccaatacca tctccgcaac ctgcgcatgc cgctgagccg
    22141 gctcgtcaaa cgtggagctg atgacttcag ctttgacctg acgctgccaa tccgtgactt
    22201 cttccgggcg ctcgtcgatc aggagaacaa tgagggtaac ttccttgtga ttcttcagaa
    22261 tggctcgggc gatcgcctgc agcaacatcg tttttccggt tcgcggagct gcgacaatca
    22321 aaccgcgctg ccccttaccg atcggcgtcg taaggtccat tacacgcgtg caatattctt
    22381 cccggtcgaa ctccagattt aaacgttcct cgggatagag cggggtgaga ttgtcgaaca
    22441 gaatcttgtc acgcgcgact tccgggtcct cataattaac tttttccacc ttgagcaacg
    22501 cgaaataccg ttcgctctct ttcggtgggc gaatctgccc cgatacgata tctccagttc
    22561 tcagattgaa gcggcggatc tgcgatgggg agatataaat atcgtcaggt cctggcaaat
    22621 agttcgaatc cggcgctcga aggaacccaa agccgtccgg caatgtctcc aagaccccct
    22681 cgccaaacac cacgccgttc ttttcggtct gcgcctgcag aatggcaaaa atgagttctt
    22741 gcttccgaag gtttgccgcg ccttcaatct ttaaatcccg ggccacgtca ttcaggtcgg
    22801 caatcgactt ctgtttgagt tccgcgagat gcataactt
//
LOCUS       DAOQPD010000062        22196 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1121_length_22196_cov_19.096879, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000062 DAOQPD010000000
VERSION     DAOQPD010000062.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 22196)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 22196)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22196
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1121_length_22196_cov_19.096879"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..249
                     /gene="prfB"
                     /locus_tag="PK063_13550"
     CDS             <1..249
                     /gene="prfB"
                     /locus_tag="PK063_13550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_155970262.1"
                     /note="recognizes the termination signals UGA and UAA
                     during protein translation a specificity which is
                     dependent on amino acid residues residing in loops of the
                     L-shaped tRNA-like molecule of RF2; in some organisms
                     control of PrfB protein levels is maintained through a +1
                     ribosomal frameshifting mechanism; this protein is similar
                     to release factor 1; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HMZ98122.1"
                     /translation="RKKEAEFNAIVGEKKDIAWGSQIRSYVFQPYQMVKDHRTGHEVG
                     QVSAVMDGDLDGFIEAYLQRKMTGGKTPQPVAMTDDDV"
     gene            324..1805
                     /gene="lysS"
                     /locus_tag="PK063_13555"
     CDS             324..1805
                     /gene="lysS"
                     /locus_tag="PK063_13555"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HMZ98123.1"
                     /translation="MDELNDQRQQRIKKLDQLRQLGVAPYGTRFEIKDRAGQLVQLHG
                     EKSKEVLEQEQVGCTIAGRIVGLRRFGKAAFAVLQDGSDRLQVYLKKDTLGDQAHQIS
                     EGLDLGDWIGVTGILFRTKTNEFTVEAKTLTFLSKALRPLPEKWHGLTDVETRYRQRY
                     VDLIANPQVHQIFALRSRIISGIRAFLIERGFLEVETPMMHPIPGGAAAKPFVTHHNA
                     LDAELYLRIAPELYLKRLIVGGFPRVFEINRNFRNEGISTIHNPEFTMLEFYVAYADY
                     QDLIILTEQLFSRLAQDILGTMTIDYQGAQINLGSPWRRWSYHQAILEVNSLPPSVLT
                     NRDEALAAAKRLGVEVSPKESLVNILNEIFEETVEPKLEQPTFITDYPIEISPLARRK
                     DSDPSLTDRFELYIAGREIANAFSELNDPLDQRERFEAQAAQHAAGDEEAHRVDEDFL
                     RALEYGMPPTAGQGIGIDRLVMLFTNQASIRDVVLFPQLRPEK"
     gene            1808..3085
                     /locus_tag="PK063_13560"
     CDS             1808..3085
                     /locus_tag="PK063_13560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HMZ98124.1"
                     /translation="MALPYEIFIGLRYLRAKRRNRTISFNTIVSIVGITLGVAALIGT
                     VGIMTGFKEDVQAKILGTTAHILVNDRMKESMVDYEEQVKKVAGVPEVLAATPFIFRQ
                     VLLTSPSGVQGIILRGIDPAREGTVTELAHNLVNGNLDDLSHSTKVVIPEKEREPNGP
                     DTAMRPGIILGKELSMRLGAFPGDTLNVVSPVGPVTGASMTPKIRQFVVVGIFQSGMY
                     EYDSSLAYIELGEAQKFFNMGATVTGIEVKVADVFRAADVARSIEQQLGFAFWARDWM
                     QMNRNLFSALKLEKTMMFLLLVLITIVASFNIVSTLTMIVTEKQREIAILKAMGATRK
                     GIMRIFMLNGLIIGCSGAAIGVPLGYAFLWLIQTFWTFDPTVYYISRIPVHVLGSDVL
                     LVAGSAILISFAATLYPSLQAAKLDPAAALRYE"
     gene            3158..3826
                     /locus_tag="PK063_13565"
     CDS             3158..3826
                     /locus_tag="PK063_13565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ98125.1"
                     /translation="MIDIVDLYKTFPMGGRELVVLNNINLRIQRGELIAIMGASGAGK
                     STLLQILGTLDRPTKGTVSFDGQNLFQLTEQQQAEFRNKRVGFVFQFHHLLPEFTALE
                     NACLPAMIQKREMADVVGEATKLLGEVGLADRLHHKPGELSGGEQQRVSVARALMQQP
                     DLVLADEPTGNLDSHTGDALFALMRQLNRSRGTTFVIVTHNEKLSAQADRIISMQDGT
                     IISS"
     gene            3934..5079
                     /gene="traF"
                     /locus_tag="PK063_13570"
     CDS             3934..5079
                     /gene="traF"
                     /locus_tag="PK063_13570"
                     /inference="COORDINATES: protein motif:HMM:NF025106.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
                     /protein_id="HMZ98126.1"
                     /translation="MNRQVMSYVQYTAVLLAVLLPLQAAAVEFVFVGSRQMGMGGAGV
                     ATTTDSLATYWNPAGMAMSKKFDMRIQGGGQVVDRGDVFDTIKDINHINLNDTSAPNI
                     ARLQQQIDRMNKPGTNLTAAASGGFYVKGNFGEHALGFNVSDVATSGGFLRGPVGFTN
                     NGTNLTVNGQFAMNGLEVRQAALSYAYAFMDRMFSIGVTGKVIQGAAYTGATNIRGAS
                     DDVKVFEDIGRAKISSALGIDVGAMFRPSSWLRMGIVAKDINAPTFDAPNGDKFKLLP
                     QVRTGIAVNPYNSLTLTADVDITKNNTLTPGVYSQVLSLGAEQTILSELLSFRLGAFK
                     NMQDAKTPFIPTAGFGIRILALRIDIAGGYDFRDQAALASGSIAVTF"
     gene            5126..5731
                     /locus_tag="PK063_13575"
     CDS             5126..5731
                     /locus_tag="PK063_13575"
                     /inference="COORDINATES: protein motif:HMM:NF024436.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98127.1"
                     /translation="MTRHTFSTISVVLCLVMTGLLAGCGGLQEMWEGPAARGFYPKTM
                     AILPISGTYDSAREDVEEVVAKVLIKSRRVEKVVPPDQVTDTFQTTKDAFDALVTYFS
                     RMETTGQSDKNSAIKIGHALGADSLLVVKVNAWEYTREEGDNIARVGLSMRLVDAVNG
                     AIVWKARHQVQESYLFIRPDMKDLATKLAADMIKYMPPEKR"
     gene            complement(5747..6802)
                     /locus_tag="PK063_13580"
     CDS             complement(5747..6802)
                     /locus_tag="PK063_13580"
                     /inference="COORDINATES: protein motif:HMM:NF024583.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HMZ98128.1"
                     /translation="MAVARRKISRTTRKTTSTNSSVAARRKTTVRKPAPIGEDRLLRT
                     LQQGLFNTLSSAEGEGRSPIGVAAVFVQLFLQLTKVQAVALYVRDEQTREMACLAEAG
                     SSDPSVTELWLEGLKKAEQNAQIVSGELHGVRLHRINRLDGVVMFRAGKSQRLPSRKL
                     LSLLTAVEPWLAVLLDHARLTVKYAAKILRIQHMEQVSDILNSSLAEEEKLRRALDAA
                     VRLVEAEAGALFLASPDGTLSLSALGGERAAGLTALHSTVAAGVHRTGQAVLITQGRQ
                     DPRLVAGQGWQAALSVASLVSVPVRMGARAVGVLEVVNRRSGKPFSNWDVLELASLSN
                     QFGLAIDNLRRGSGVRA"
     gene            complement(7003..>7752)
                     /gene="trpA"
                     /locus_tag="PK063_13585"
     CDS             complement(7003..>7752)
                     /gene="trpA"
                     /locus_tag="PK063_13585"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HMZ98129.1"
                     /translation="ALITYIMAGDPSLQDTEQLVLELERAGADIIELGVPFSDPIADG
                     PVIQQAAERGLQSGTSLRRILESVTRLRDMTQIPIVLMAYYNNIHAFGEADFCSKAAA
                     AGVDGLIVPDMPPDEAGPLREPAAAADLHLIFLLAPTSTASRRAYVAKESGGFVYYVS
                     ITGITGAKLNDMAGVRDNVAKIRKHTKTPVAVGFGVATPEDAARVAETADGVIVGSAI
                     VRRVGEHGQDGRLVHEVGSFVRSLKAAMQPG"
     assembly_gap    7753..7852
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<7853..8994)
                     /gene="trpB"
                     /locus_tag="PK063_13590"
     CDS             complement(<7853..8994)
                     /gene="trpB"
                     /locus_tag="PK063_13590"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HMZ98130.1"
                     /translation="MAIPDRHGRFGPYGGRYVPETLMPALLELEAAYQRTRKDKSFQA
                     ELKHYLTEYVGRPTPLYFAQRLTKRLGGAKIYLKREDLCHTGAHKINNAIGQALLARR
                     MKKPRLIAETGAGQHGVATATVAAMFGLECEIYMGTEDMQRQALNVFRMRLLGSKVTG
                     VDAGSRTLKDAISEAMRDWTTNVRTTHYVLGSVLGAHPYPMMIRDFQAVIGREARKQI
                     LSAEGRLPDCLIACVGGGSNAMGLFHAFVPDKKVRMVGVEAAGLGVESGKHAARFAGG
                     RPGVLQGTMTYLLQDENGQVNLTHSVSAGLDYAAVGPEHSYHKETNRAEYTSATDDEA
                     LAAFDLLAREEGIMPALESAHAIAEVVKCAPRMKKNQIIVVNLSGRG"
     gene            complement(9083..9715)
                     /locus_tag="PK063_13595"
     CDS             complement(9083..9715)
                     /locus_tag="PK063_13595"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004640 - phosphoribosylanthranilate
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HMZ98131.1"
                     /translation="MTVKVKICGLTNAEDAAVAVEAGADAVGFVFHKKSPRCAETEAV
                     KAIVKELPPFVLPIGVFVNEEAKVVRDIMDSCGLALAQLHGDETAAYCESLGRPVLKA
                     IRLRDRRSFLALAEFQGRAGVRGFLVDAFSPDAYGGTGQVADWSLAAEAASVARILLA
                     GGLTPDNVIQAIEQVHPYGVDVSSGVEAKPGKKDHAKVRAFLEAVKRLPR"
     gene            complement(9719..10033)
                     /locus_tag="PK063_13600"
     CDS             complement(9719..10033)
                     /locus_tag="PK063_13600"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98132.1"
                     /translation="MRTLLLFGLMAMGLTVAGCVNQEIHEYSPKWDSWMGSTKDDRIK
                     EMGIPTRCHSFKDGGEVCEWMIPQQDGRQDLIGLTFNPKGQACQWSYRGFYGMQKSKT
                     SC"
     gene            complement(10030..10854)
                     /gene="trpC"
                     /locus_tag="PK063_13605"
     CDS             complement(10030..10854)
                     /gene="trpC"
                     /locus_tag="PK063_13605"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: protein motif:HMM:NF001377.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HMZ98133.1"
                     /translation="MILDRILEHKKAELRHKSSRGYLADLKTRIRDAGPTLGFAVTLD
                     ARRTADRPALIAEVKKASPSLGLLRPEFEQRFEPVKIAEAYREHGASAVSVLTDKDFF
                     QGDLAYLADVKRTVGLPALNKEFMVADIQFYEARAYGADAVLLIVAGLEKRQLIDFSA
                     LAKELSLDVLVETHHERELDTVLEWLPDVRLIGINNRDLKTFSTDLGVTLRLAKRIPA
                     DKMIVSESGIHTRKDVERLVEAGVHAMLIGESLIRAQDTGAKIRELLGDPPTKEQS"
     gene            complement(10859..11875)
                     /gene="trpD"
                     /locus_tag="PK063_13610"
     CDS             complement(10859..11875)
                     /gene="trpD"
                     /locus_tag="PK063_13610"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HMZ98134.1"
                     /translation="MIKDAINKLAERADLTEQEAETVMGEIMDGSATCAQIAAYLMGL
                     RMKGETVEEIAGSVLAMRARATHIRVKDSLVLDTCGTGGDRAHTFNISTTAAFVVAGA
                     GITVAKHGNRSVSSKSGSADVLAALGVAIQLPPEQVADCVNEVGIGFLFAPLYHSAMK
                     HCAQPRQELGIRTLLNILGPLTNPAGARLQVVGVFDAGLTELLAKVLVHLGAQHCFVV
                     HGMDGLDEITVTDRTRISEGKAGVVSSYTIDPAEFGLARVRPKDLVGGNAEDNAAITR
                     DIFRGRKGPKRDIVCLNAASALVAGRKAKTLQEGFELAQRTIDAGAAMEKLEQLIAFT
                     KKAS"
     gene            complement(11915..12478)
                     /gene="pabA"
                     /locus_tag="PK063_13615"
     CDS             complement(11915..12478)
                     /gene="pabA"
                     /locus_tag="PK063_13615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HMZ98135.1"
                     /translation="MLLMIDNYDSFTYNLVQYFGELGEDVVVYRNDKISIPEMESLKP
                     SRLVISPGPCTPSEAGVSVEAIKHFGGKLPLLGVCLGHQSLAVAFGGEVIRAERLMHG
                     KTSMVRHDGRTLFRGLPNPFEATRYHSLIVNRKNLPDCFEISAETAEGEIMGMRHKTL
                     GIEGVQFHPESILTTAGKELLRNFLKL"
     gene            complement(12526..14022)
                     /gene="trpE"
                     /locus_tag="PK063_13620"
     CDS             complement(12526..14022)
                     /gene="trpE"
                     /locus_tag="PK063_13620"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HMZ98136.1"
                     /translation="MTKQQYSLTLDEFRGLATEGNLIPLYREILADYETPVSAFAKID
                     QGPTAYLLESVAGGENWARYSFLGSGSSAVIHEEKGDLILTRGKKRLKIQSRGNPLER
                     VRELMEEYRPVTVPGLPRFVGGAVGYLSYDVVRTFEELPSLRKDSLGMPEVAFLLTDT
                     LLIFDNVSQKIKVVANAYLESTTDRAVREAYRHATARIDKMIARLKRPVRQPRVKRRR
                     KPITFTPNMNRADFEKMVTRTKEYIRAGDIVQAVLSQRWETQIHTTPFQLYRALRVVN
                     PSPYMYYLRVAGVELVGSSPETLVRCEDGQISLRPIAGTRRRGNSPDEDQDLARSLLA
                     DEKERAEHVMLVDLGRNDVGRVAARGSVKVDSLMQVERYSHVMHIVSQVTGQLEKGKS
                     VYDVTRACFPAGTVSGAPKIRAMQIIEELEPTRRGPYAGAVGYFGFSGNMDMCINIRT
                     VVIKGRQAYIQAGAGIVADSVPEHEYEETCNKARAMMKAIELAEQGLE"
     gene            complement(14044..14730)
                     /locus_tag="PK063_13625"
     CDS             complement(14044..14730)
                     /locus_tag="PK063_13625"
                     /inference="COORDINATES: protein motif:HMM:NF013630.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HMZ98137.1"
                     /translation="MMSEQQGRLRRRSVVPIGLLILGSLGLGGCVMSEKYEAEKARSL
                     NFQRLLAQEEKRSAELDAEVKRGKRELSEYEARNRELGAQVEAVRQQAAQIQEEAQAM
                     KEASLLEKRAHEDMKRLTTIPKAKKAAPKKDFAAAVDEALKTEVPSDLSLEPATGAAK
                     DALTHSDLMDGAGATAAAATGTTHTVRPGETLYRIGQKYHVAPDQLRKWNNLKDNTVG
                     VGQKLIVSQP"
     gene            14966..15919
                     /locus_tag="PK063_13630"
     CDS             14966..15919
                     /locus_tag="PK063_13630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HMZ98138.1"
                     /translation="MASGAQPASSRVISIEGITLHLAQPMSMGQEWIGSREILKQLLA
                     CWLVIDERDLPLSPRITGQPGIGKTTLAMAGARERKQDLYVFQCTADTRPEDLLITPV
                     LAESGTISYHASPLVTAVLTGSICVLDEGNRMNEKSWASLAPLLDHRRCVESIIAGIL
                     IKAHADFRCCVTMNEDASTYEVPDYILSRLQPTLGMGFPAREDELAILRYHLPFAPAE
                     MLALTVEFLQEAHQLSLEYSVRDGIHLLQYALKRRAQDPTDPLSVDAAWRESLIKVLG
                     EEALDLPMQSRRRKRALGDQALPQGLGDFFFGSDDPLHPGR"
     gene            15919..17817
                     /locus_tag="PK063_13635"
     CDS             15919..17817
                     /locus_tag="PK063_13635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98139.1"
                     /translation="MAAPSSTADDVFRLSPRIELFPVLHGSGDVAQEVRDRLTDRRYD
                     CLAVPLPPSFEHPLEEAVVDLPTISVIVQQEPDSETGATVNYVPVDPCQAVVMGIRVA
                     IGEGMYRAYIDRETSVVEPIPFVSPDAYALKRLPYAAFAASMVPTLTTPAEGSQQQAR
                     IAWMAFQLHQLELEYERILCLCHFADWPWIRQAYQQRADYHEPDADIRRPEQYLVEPA
                     SLYFVLGELPFLTELYERRRATVHSDRHLSIDGIKELLIETRARWQTAHDEEGHTVPN
                     WVTPQLLQLYLQYVRNHALLDRRLTPDLYTLVLAAKQMAGDDFAIRLLETAKSYAYQE
                     IEGKHLPQLSAGLGQFALPDEQIVRATNRLQGAPVTWRSLSLRPRPPRRTSQRWSYLW
                     NPNRQCSWPPEDSKIESFHTHVRDQAKAIIGADLAKSEKFTTSMKDGIDIRESLRHWH
                     QRAKPGRPNRLELYVKEIPPARGNVDTVIFLFDTPADPDQYSWQATWYAEHAQESTLC
                     FYATPFLNNMIAPGIGQSLYGGALFIFPPRPIPDIWTDEALGFATTLEERLIAAGAAH
                     SHETHVALVTPVPPKARWRQIASRSGRRLVPIPLSRFSGQLIDRLRRFHVLNGQDIRS
                     FAAQFIRE"
     gene            17810..19837
                     /gene="ligA"
                     /locus_tag="PK063_13640"
     CDS             17810..19837
                     /gene="ligA"
                     /locus_tag="PK063_13640"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: protein motif:HMM:TIGR00575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HMZ98140.1"
                     /translation="MSNPPMADRSIEQRITALRREIRHHDHLYYTKDRPEISDAEYDR
                     LFRELVDLETAHPDLITADSPTQRVGAPPLSELTKVSHEKPMLSLDSIVDQEDVRAFD
                     QRMKRELETDQPVYTAEPKFDGLSVELVYDQGRFVRGATRGDGMIGEDVTVNLRTIRS
                     LPLQLHAETGPPAHLVVRGEVYMRLDEFQSLNRRMTERGEEGFANPRNAAAGSLRQLD
                     SRITASRPLTVTCYDIMAIAGPMPATHWDELEALAAWGLPVPEHRQRCRSIDEVLTFH
                     QTTDAMRDDLPFEIDGVVVKLDRRDWQDQLGSKSRSPRWAIAYKFAPRKEITVIQDIA
                     VSVGRTGTLTPLALLKPVEVGGVTISRATLHNADEVARKDVRVGDTVKVERAGDVIPA
                     IAERVPVPGEERQAPFVMPDHCPVCGSAVAREGAYFYCTGQTVCMAQLKGAIEHFASK
                     SALNIDGLGKKTVAQLVDAGMVKDLADLYSLTKEQLLTLEGFADRSASLLMDSIERSK
                     AVSLERLLMGLGIRQVGQHIARVLAKHFGTLPRVMEATQDELLHVREIGPEISESLAS
                     FFTEARNREVIERLVARGLTVAPPVAEASPGGRTLTGKTFVFTGGLAAYSRDQAKELV
                     ERQGGQVSSSVSKKTAYVVAGIDPGSKLDQAQKLGVKILTEAEFTDLVTPG"
     gene            complement(19812..21125)
                     /locus_tag="PK063_13645"
     CDS             complement(19812..21125)
                     /locus_tag="PK063_13645"
                     /inference="COORDINATES: protein motif:HMM:NF013741.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HMZ98141.1"
                     /translation="MDIIVLIFLILLSAVISVVEVGFYSVNDTKLRALADTGSKRAEM
                     ALHLRTDPQRLLLTILVGDRLVDTATASLATIIALNRFGGQGLEGVLGEAFAVLVGIL
                     TFVLLVFADLVPKTLAAKYSVPVVLNMAYPAYAAQQVLTPIMFFVVPLIYKLTGGKGL
                     NVPFVTEEELKIMLDQSSKSGAIEAQEVKMIKNVFQLKDITAEDCMTPRIYMFSLDCN
                     QYLREAKELLFKSKYSRIPLYEGTLDNIIGILYKTKALTALAQGHTEMKLRDIAQPAL
                     FIPHTKSADDLMKQFQLDKRHMAIVVNEFGGVMGLVTLEDLLEEVVGEIVDETDITEE
                     LIKRIGKNQILVHGRTEVRKVNDFLKVDLGDDAVTISGLVQHELGRIPKVGEEVHIAN
                     CRLVIHEADPRVIKSVQIYKEDKHPALPDQPVEEHVPVTQASPDR"
     gene            complement(21390..>22196)
                     /locus_tag="PK063_13650"
     CDS             complement(21390..>22196)
                     /locus_tag="PK063_13650"
                     /inference="COORDINATES: protein motif:HMM:TIGR00413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septal ring lytic transglycosylase RlpA family
                     protein"
                     /protein_id="HMZ98142.1"
                     /translation="CRTPPKPSGCCAPIHSTNFSGLSLFFSILRIRLTPGEKRTSTSR
                     LLLPLFALLLTTWLHGCSGWSPARPSYPPGYPLGFVERGSASWYGPGFHGNRTANGEV
                     YDMHKLTAAHRTLPLGSVAVVRSLTTGRQVTVRINDRGPFARGRILDLSLAGAQAVGM
                     VGRGTDEIELRVISYQGRAGEMGWLRVQVGSFADPSNAQALVQRLRNAYPGSRAVAVD
                     LPDGRRYRVYAGQFRTEADAEQAAAHLKRALDTDPFIVRDDSESPATGNP"
BASE COUNT         4518 a         6885 c         6246 g         4447 t
ORIGIN      
        1 cgcaagaagg aagccgagtt caacgcgatt gtcggcgaga aaaaagatat cgcctggggc
       61 agccagattc gctcctacgt cttccagccg taccagatgg tcaaagacca tcgcaccggc
      121 cacgaagtcg gccaagtgtc tgcggtaatg gacggcgacc tggacggctt catcgaagcc
      181 tatctgcaga gaaaaatgac cggcggcaag actccccagc cggtggccat gacagatgac
      241 gacgtataaa ctgtgacccg cctctcgtga cgcctggtgc ccgcgtcacg tgtgaagagc
      301 gacgaacgac gagagaccca tccatggatg aattaaacga tcaacggcaa caacgcatca
      361 agaaactcga ccagctccga cagctcgggg tcgcgcccta tggcacgcgc ttcgagatca
      421 aggaccgcgc cgggcagctc gtgcagctgc atggggaaaa gagcaaggag gtgctcgagc
      481 aagaacaggt cggctgcacc atcgccggcc gtatcgtcgg gttgcgccgg ttcggcaaag
      541 ccgcgttcgc cgtgttgcaa gacgggtcgg accgtctcca ggtctatttg aagaaagaca
      601 cgctgggtga ccaggcccac cagatttccg agggactgga tctcggcgac tggatcggcg
      661 tgaccggtat cctctttcgc accaagacca acgagttcac cgtcgaggcg aagacgctca
      721 cgtttctcag caaggctctc cgcccgttac cggaaaaatg gcatgggctg acggatgtcg
      781 aaaccaggta tcggcaacgg tatgtcgact tgatcgcgaa cccgcaagtg catcagattt
      841 tcgcactccg cagtcgcatc atctctggga tccgcgcctt tctcatcgag cgtggcttcc
      901 tggaagtgga aacgccgatg atgcatccga ttcccggagg cgcggcggcc aaaccctttg
      961 tcacccatca caatgccctg gatgctgaac tgtatctccg catcgcgccg gagctgtacc
     1021 tcaaacggct gatcgtcggc ggatttcccc gcgtgttcga aatcaatcgc aacttccgga
     1081 atgaaggcat ttcgacgatt cacaatccag aatttacgat gctggagttt tacgtcgcct
     1141 atgccgacta ccaggacctc atcatcctga ccgaacaact cttcagccga ttggcgcagg
     1201 acattctggg gacgatgacc atcgactatc agggcgcgca gatcaatctg ggatctccct
     1261 ggcgccgctg gtcctaccat caggcgatcc tggaagtgaa cagtctgccc ccctcggtcc
     1321 tcacgaatcg cgacgaagcc ctcgccgccg ccaaacggct cggtgtcgag gtgtccccga
     1381 aggaatcgct cgtcaacatc ctcaacgaga tctttgaaga gaccgtcgaa ccgaaactcg
     1441 aacaaccaac ctttatcact gactatccga ttgaaatttc ccccctcgca cgacgcaagg
     1501 attccgatcc ttcgttgacc gaccggttcg agctgtacat cgccggccgc gaaatcgcca
     1561 acgccttttc cgagttgaac gatccgctcg atcagcgcga gcgcttcgaa gctcaggccg
     1621 cccaacatgc ggccggcgac gaggaggccc atcgggtgga cgaagacttc ctgcgcgcgc
     1681 tcgaatacgg catgccgccg actgccggcc aaggcatcgg catcgaccgt ctcgtcatgc
     1741 tcttcaccaa tcaggcttct atccgggatg tcgtgctctt cccgcaactc aggcctgaaa
     1801 agtagacatg gcgcttccct acgaaatctt catcggcctg cgctacctgc gcgccaagcg
     1861 gcgtaaccgc actatctctt tcaatacgat cgtgtccatc gtcgggatta cgctcggcgt
     1921 cgcggccttg atcggcaccg tcgggatcat gacggggttc aaggaggatg tgcaggcgaa
     1981 gattctcggc accacggccc atattctcgt gaacgaccgt atgaaggaat cgatggtcga
     2041 ttacgaggaa caggtgaaga aggtcgcagg tgttccggag gtgctggcgg ccacgccgtt
     2101 tattttccgg caggtcctgc tcacgtctcc atccggcgtc caaggcatca tcctgcgcgg
     2161 aatcgatccg gcgcgtgaag gcactgtgac cgagctcgcg cacaacctgg tgaatggcaa
     2221 cctcgacgat ctctcacatt ccaccaaagt tgtcattccg gaaaaggaac gcgagccgaa
     2281 cggaccggat accgccatgc ggccgggcat catcctcggg aaagagctgt cgatgcgact
     2341 cggcgccttc ccgggagaca cgcttaatgt ggtctctccg gttggacccg tgaccggcgc
     2401 cagcatgacg ccgaaaattc ggcaattcgt cgtggtcggc atcttccaat ccggcatgta
     2461 cgaatacgat tcgtcgctcg cgtatatcga actgggagag gcacagaaat tttttaacat
     2521 gggcgccaca gtgacaggca tcgaggtcaa agtcgccgat gtgtttcgcg ccgccgacgt
     2581 ggcccggtcg atcgagcagc agcttggctt cgccttctgg gccagggact ggatgcaaat
     2641 gaaccgcaac ctgttctcgg cgttgaaact ggaaaagacg atgatgtttt tgctgttggt
     2701 gttaatcacg attgtggcgt cattcaacat cgtcagcacc ctgacgatga tcgtgacgga
     2761 aaaacagcgc gagattgcga tcctcaaggc gatgggtgcg acgcgtaaag gcatcatgcg
     2821 gattttcatg ctcaacggcc tgatcatcgg ctgttcaggc gcggccatcg gcgtgccgct
     2881 gggatatgcg tttctctggt tgattcagac gttttggacc ttcgatccca cggtctatta
     2941 catctctcgt attccggtcc atgttctggg gtcggatgtg ttgctggttg caggctcggc
     3001 tatcctgatt agttttgccg ccaccctgta tccatcgctc caggcggcaa aactcgaccc
     3061 ggccgccgcg cttcgctatg agtgacgcgt atggcatgcc aagacatcga ccagcgtgaa
     3121 gcagtgatca tccacgattc catagcgcag tgaccgcatg attgacattg tcgacctcta
     3181 caaaacgttt cccatgggcg gccgcgagtt agtggtgttg aataacatca acttgcggat
     3241 tcagcgcggc gagctcatcg ccatcatggg cgcgtcagga gccggcaaga gcaccctcct
     3301 tcaaatcctc ggcacgctgg atcgccccac caaaggcacc gtgtcgttcg acggacagaa
     3361 tctctttcag ctcaccgagc aacagcaggc ggagttccgc aataaacggg taggattcgt
     3421 ctttcagttt caccacctgc tgccggaatt cacggcgctc gaaaatgctt gtttgccggc
     3481 aatgattcag aaacgcgaga tggccgatgt cgtcggcgaa gccacgaagc tcctcggcga
     3541 ggtcggtctg gccgatcgcc tgcaccacaa accgggcgaa ttatccggtg gcgaacagca
     3601 gcgggtgtcc gtcgcgaggg ccttgatgca gcaaccggat ctcgtattgg ccgatgaacc
     3661 gacgggcaac ctcgacagcc ataccggcga cgcgctcttc gccctcatgc gtcaattgaa
     3721 tcgctcccga ggtacaacat tcgtcatcgt cacgcacaac gagaaactct ccgcccaggc
     3781 cgatcgcatc atctccatgc aggacggcac gattatttcg tcgtagacga cacgtcaccg
     3841 accagctccg ggcggcaatc atttcttgac ggcttcagca tgttttcgta gactgcgcca
     3901 tcgatccttc cgagccggag ttctactgaa tctatgaaca gacaggtcat gtcctacgtt
     3961 caatacacag ccgtcctgct tgccgtcttg ctgccgctgc aggcggcggc agtggaattt
     4021 gtgtttgtcg gatcacggca gatgggtatg gggggagccg gagtagccac gacgaccgac
     4081 tccctcgcca cctattggaa tcccgccggc atggcgatga gcaagaaatt cgatatgcgg
     4141 attcaaggcg gtggccaggt ggtggatcgc ggtgacgtct tcgatacgat caaggacatc
     4201 aaccatatca atttgaatga tacctccgcc cccaatatcg cccggctgca acagcaaatc
     4261 gatcggatga acaaaccggg cacgaacctg acggcagccg cctccggcgg attctacgtc
     4321 aagggcaact tcggcgaaca tgccttggga ttcaatgtct cggatgtcgc cacatccggc
     4381 ggctttctgc ggggcccggt ggggtttacg aataacggca cgaatcttac cgtcaacggg
     4441 caattcgcca tgaacggcct ggaagtccgg caggcggcgc tgtcctatgc ctatgcgttc
     4501 atggaccgaa tgttttccat cggcgttacc ggcaaggtca tccaaggcgc ggcctatacc
     4561 ggcgccacca atattcgcgg cgcgagcgac gacgtaaagg tcttcgaaga catcgggcgc
     4621 gcaaaaatct cgagtgcgct cggcatcgac gtgggcgcca tgttccgccc ttcgtcctgg
     4681 ttgcggatgg gcatcgtcgc aaaggatatc aacgcaccga cgttcgatgc cccgaacggc
     4741 gacaaattca agctattgcc acaggtccgg accggcatcg ccgtgaaccc gtacaactcc
     4801 ctcacattga ccgcggatgt ggacattacg aagaacaaca ccctgacgcc cggggtgtac
     4861 agccaggtcc tcagtctcgg cgcagaacag acgattctct ccgaactgct gtcgttccga
     4921 ctcggcgcgt ttaaaaatat gcaggatgcg aaaacaccct ttatcccgac ggcaggcttc
     4981 ggcatacgta tcttggcctt gcgcatcgat attgccggcg ggtatgattt cagggaccag
     5041 gctgcactgg cctcgggatc catcgccgtg actttctaag gtcgcgtctg cagtgaatca
     5101 atctgctaca cttattgtac gaaccatgac tcgacacaca ttttccacga tcagcgttgt
     5161 gctctgtctc gtgatgaccg gactgctggc aggctgcgga ggcttgcagg agatgtggga
     5221 aggaccggct gcgcggggtt tttacccgaa aacgatggcg attctgccca tctccggcac
     5281 ctacgacagc gcgcgtgaag acgtggaaga agtggtcgcg aaggtgctga tcaagagccg
     5341 ccgggtcgaa aaagtcgtcc cgcctgatca ggtcaccgac acgttccaga cgaccaaaga
     5401 cgctttcgat gcactcgtga cctatttttc gcgcatggaa acaaccggcc aatcggacaa
     5461 gaattccgcg ataaagatcg ggcatgccct gggcgcggat tccctgttgg tggtcaaggt
     5521 gaatgcgtgg gaatacacaa gagaggaagg cgataacatc gcacgcgtcg gcttgagtat
     5581 gcgactggtg gacgcggtca acggcgccat cgtctggaaa gcacgccacc aggtgcagga
     5641 aagttatctg ttcatccgcc cggatatgaa ggacctggcc accaaactgg cggccgacat
     5701 gatcaagtac atgccgccgg aaaaacgctg accctctgtg cgcccgtcac gccctgacgc
     5761 ctgatcccct tctcagattg tcgattgcca gcccgaactg attggagaga ctcgccagct
     5821 ccaacacgtc ccagttgctg aatggtttac cactgcgccg attgaccact tccaacaccc
     5881 ctactgcccg cgcgcccatg cgaaccggaa cagacacgag cgaagcgacc gagagagcgg
     5941 cttgccatcc ctgccctgca accagtcgcg gatcctgacg gccctgagtg atgagcactg
     6001 cctgacccgt gcgatggact cctgcggcaa cggtcgaatg caaggctgtg agtcctgcgg
     6061 cgcgttctcc gccgagagca gacaagctca atgtcccgtc gggggatgcg agaaacaacg
     6121 caccggcttc ggcttcaacc agccgaaccg ccgcatccag ggcccgtcgc aatttttcct
     6181 cctctgccag agaggaattc aagatatcgc tcacctgctc catgtgctga atgcgaagga
     6241 tcttggcggc atatttgacc gtcaacctgg cgtggtccag caggaccgcc agccaaggtt
     6301 ccaccgccgt cagcagtgac aggagcttgc gcgagggcaa tcgctgggac ttccctgccc
     6361 ggaacatgac caccccatcc agccggttga tccggtgtaa tcgaactcca tgcagctcgc
     6421 cactgacaat ttgagcattc tgctccgctt tcttcagtcc ctccagccac aactccgtca
     6481 ctgagggatc gctgctgccg gcttctgcca gacaggccat ctcacgggtt tgctcgtcgc
     6541 gtacgtagag cgcgacagcc tggaccttgg tcagctgcag gaataactgt acgaataccg
     6601 cagccacccc gattggcgaa cgcccctcac cttctgcact cgacagggta ttgaacaaac
     6661 cctgctgcag cgtacgcagg agccggtctt ctccaatagg agctggcttg cggacggtgg
     6721 tttttctccg cgcggcgact gatgagttcg tggatgtcgt cttacgggtg gtacgactga
     6781 tcttccggcg agctacggcc atggcatctc ctcatgtgaa ccatcgatcg ttgcaggaca
     6841 gagcgtaacc gctctgcatg attgttgctg gaattgatag cgggtgagga agcgagatgg
     6901 atgcgagtca ggcctgatgc ggacgagtcg cctgcaatcg gcctgcaaat agagttcgaa
     6961 actatcgaag gtgatgacga gcggatgccg atgcgaaccc ggttatccgg gctgcatcgc
     7021 agctttgaga gagcgaacga aggaacccac ttcgtgaacg agtcggccat cctgcccatg
     7081 ttctccaaca cgacggacaa tcgcactccc gacgatgacg ccatccgcag tctcagcaac
     7141 ccgcgcggca tcctccggcg tggcgacccc gaatcccacg gcaacgggtg tcttggtgtg
     7201 ctttctaatc ttggcgacgt tgtctcgcac gcccgccatg tcgttcagtt tagccccagt
     7261 gatgcctgtg atggaaacat aatagacaaa tccgccggac tccttcgcca cgtaggcccg
     7321 gcgtgacgcc gtgctggtcg gtgccaggag aaaaatcagg tgcaagtcag ctgcagctgc
     7381 cggctcgcgg agaggcccgg cttcatcagg tggcatatcc ggaacaatca gaccgtcgac
     7441 tccggccgcg gcagccttgc tgcaaaagtc cgcctcgccg aacgcatgaa tgttgttgta
     7501 ataggccatc aggacgatag ggatctgggt catgtcgcga agacgcgtca cggattcgag
     7561 aatcctgcgg agcgaggtac cgctttgcaa tccccgttcg gctgcctgtt gaatcaccgg
     7621 tccatccgcg atgggatcgg aaaaggggac acccaattca atgatgtcgg cccctgcccg
     7681 ctccagttcg agcaccaact gttccgtgtc ctgcaatgaa ggatcaccgg ccatgatata
     7741 ggtgatgagg gcnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnccacgtcc
     7861 cgacagattc accacgatga tctgattctt tttcatgcgg ggcgcacact tcaccacctc
     7921 agcgatggcg tgggcgcttt ccagtgccgg catgatcccc tcttcccgcg caagcaagtc
     7981 gaaggcggcc aaggcctcat cgtccgtcgc cgatgtgtat tctgcccggt tggtttcctt
     8041 gtgataacta tgctccggtc ccaccgccgc atagtccaac cctgccgaca cggaatgggt
     8101 aagattgacc tgaccgttct cgtcctgcag caggtaagtc atggttccct ggagcacgcc
     8161 tggacgcccg cctgcgaacc gagccgcgtg tttgccgctc tccacaccaa gccctgcggc
     8221 ttccaccccg accatcctca ccttcttgtc cggcacaaag gcgtgaaaca accccatggc
     8281 attgctaccg cccccgacgc aggcgatcag acaatcaggg agccgtcctt ccgcggacag
     8341 aatctgtttg cgagcctcgc gcccgatcac ggcttgaaaa tcgcggatca tcatcggata
     8401 gggatgcgca ccgaggacgg agccgagcac ataatgggtg gtccgtacat tggtcgtcca
     8461 atcccgcatg gcttcgctga tggcatcttt taaggtccgg ctgccggcat ccacacccgt
     8521 gacttttgaa ccgagcaacc tcatccggaa cacgttcaac gcctgccgct gcatgtcctc
     8581 cgtgcccatg tagatttcgc attcgagccc gaacatcgcc gccaccgtcg ccgtcgccac
     8641 tccatgctga cccgcgccgg tctcggcgat gagccgcggc ttcttcattc ggcgcgcgag
     8701 caacgcctgg ccgatggcgt tgttgatctt atgggcaccg gtatgacaga gatcttcccg
     8761 cttcaaataa atctttgcgc cgcccagccg cttcgtcagg cgctgagcaa aatacagcgg
     8821 cgtcgggcgt cccacatatt ccgtgagata atgtttcagt tcggcttgaa agctcttgtc
     8881 cttgcgggtg cgctgatacg ccgcttccag ctccagcaac gccggcatca gagtttcagg
     8941 cacatatcgc ccgccgtagg gtccgaaccg cccatgtcga tctggtatcg ccatgtgtct
     9001 tccttcagct aatcgtaaaa gtgaaagtat aacaggatga tgaaaacgtc cgccagcctc
     9061 gggcccacaa cgaagggaac tattatcgcg ggagccgctt cacggcttcc agaaacgccc
     9121 ggacttttgc atgatctttt tttccgggct tcgcttccac gccgctgctg acgtcgacgc
     9181 catatggatg aacctgctcg atggcttgaa taacgttgtc gggagtcagc ccgccggcga
     9241 ggagaatgcg cgcaaccgat gcagcttcgg cggccaatga ccaatcggcc acctgccccg
     9301 tgccgccata ggcgtcggga gaaaaggcat ccactaaaaa accgcgcaca ccggcgcggc
     9361 cctgaaattc tgccaacgcc aggaacgatc gacgatctct gaggcggatg gctttgagaa
     9421 ccggccgtcc caacgattcg cagtaggccg cggtctcgtc gccgtggagt tgcgccaggg
     9481 ccagaccaca gctatccatg atgtcccgca cgaccttggc ctcttcattc acgaagacgc
     9541 cgatcggcag gacgaaggga ggcaattcct tgacgatcgc cttcacggcc tccgtttccg
     9601 cacagcgggg actcttcttg tggaagacga acccgacggc gtcagcgccg gcctcgacag
     9661 ccaccgctgc atcctccgcg ttcgtcaacc cgcagatttt taccttcacg gtcatgcgtc
     9721 aacaactcgt cttacttttt tgcatcccgt aaaatccgcg ataggaccac tggcaggctt
     9781 gccccttggg attgaaagtc aggccgatca aatcctgtcg cccatcctgc tgagggatca
     9841 tccactcgca cacttcgccc ccgtctttaa acgaatgaca gcgcgtgggg atgcccatct
     9901 ctttgatccg gtcgtctttc gtgctgccca tccaggaatc ccacttggga gagtattcat
     9961 gaatttcctg atttacgcag ccggccaccg tcaatcccat cgccatcaga ccgaacaaca
    10021 gcagcgtcct catgattgct ccttggttgg cggatcaccc agcagttcgc gaatcttcgc
    10081 cccggtatcc tgcgcgcgaa tcaacgattc gccgatcagc atggcgtgga cgccggcttc
    10141 gaccaaccgc tcaacatcct tgcgtgtgtg gattccgctt tcgctgacga tcatcttgtc
    10201 ggcgggaatc cgtttcgcca ggcgaagggt cacgccgagg tctgtcgaga aggtcttgag
    10261 atcgcggtta ttgatcccga tgagccgtac gtccggcaac cattcgagca ccgtgtcgag
    10321 ttcgcgctca tgatgcgtct cgacgagcac atcaagagac agctctttgg ccaatgccga
    10381 aaagtcgatc aactggcgtt tttccagacc ggccacaatc aacaggactg catcggcgcc
    10441 ataggcccga gcctcgtaaa actgaatgtc cgccaccatg aattctttgt tcagcgcggg
    10501 aaggcccact gtgcgcttca catcggccaa atacgccagg tcgccttgga aaaaatcctt
    10561 gtccgtcagc acggacaccg ccgacgcgcc atgctcgcgg tacgcttcgg caatcttgac
    10621 cggctcgaag cgttgctcga actcgggccg caaaaggccg agactcggcg acgctttctt
    10681 cacttccgca atgagcgccg gcctgtcggc ggtgcgtcgc gcgtcgagcg tgaccgcaaa
    10741 ccccagcgtc ggacctgcgt cgcggattct ggttttcagg tcagccagat acccgcggct
    10801 gctcttatga cgaagttccg ctttcttgtg ttcgagaatt cggtcgagaa tcacggtgtc
    10861 acgaggcctt cttggtaaat gcgatcagtt gttccaactt ttccatggcc gcccctgcgt
    10921 cgatcgtccg ctgagccagc tcgaaccctt cttgtaacgt cttcgccttg cgccccgcga
    10981 cgagtgcgga cgccgcgttg aggcagacga tatcgcgctt cgggcctttg cggcccctga
    11041 aaatgtcccg cgtgatggcg gcgttgtctt cggcgtttcc cccgacgaga tccttcggcc
    11101 tgacgcgcgc gagtccgaac tctgcggggt cgatcgtgta actcgacacg acgcccgcct
    11161 tgccctctga aattctggtg cgatccgtca cggtaatttc gtccaggccg tccatcccgt
    11221 gcaccacaaa acaatgttgc gcgccgagat gcaccagcac cttggccagc aactcggtca
    11281 ggccggcatc gaagaccccg acgacctgga gacgggctcc agccggattg gtgagcgggc
    11341 cgagaatatt cagcaacgtg cgaatgccca gctcctgccg gggctgggca caatgtttca
    11401 tggcgctgtg gtacaagggt gcaaacagga aaccaatgcc cacctcgttg acgcaatcgg
    11461 ccacctgttc aggcggcagc tgaatggcga cgcccagggc ggccagcaca tcggcgcttc
    11521 cggacttcga cgacacggag cgattgccat gcttggcaac cgtgattccc gctcccgcga
    11581 ccacgaaggc cgccgtcgtc gatatgttga aggtgtgggc ccgatcgcct cccgtgccac
    11641 acgtatctag cacgagtgaa tccttgaccc gaatgtgcgt cgccctggcg cgcatggcca
    11701 agacagagcc ggcgatctct tccaccgtct cgcctttcat gcgcaggccc atgaggtacg
    11761 cggcaatctg cgcgcaggtg gcggatccgt ccatgatctc gcccatcacc gtctcagctt
    11821 cctgctccgt caggtcagcc cgctcggcga gtttgttgat ggcatctttg atcatgggta
    11881 taacacgatg ggaggcggcg caccggccct cacgctataa cttgaggaag ttgcgcagca
    11941 gctccttacc ggcggtggtg agaatcgatt cgggatggaa ttgcacccct tcgatgccca
    12001 gcgtcttgtg ccgcatgccc atgatttcgc cctcggcggt ttccgcgctg atctcgaaac
    12061 aatcaggcag attcttccgg ttcacgatga gcgaatggta ccgcgtggct tcgaagggat
    12121 tcggcagacc acgaaacaag gtccgcccgt cgtggcgcac catcgaggtc ttcccatgca
    12181 tgagacgctc ggcacgaatc acctccccgc cgaacgcgac ggcaagggat tgatggccca
    12241 ggcacacgcc cagcaatggc aacttgccgc cgaagtgctt gatggcctca accgacacgc
    12301 cggcttcact gggggtgcag gggcccggcg aaatgaccag ccggctcggc ttcaaggatt
    12361 ccatctccgg gatggaaatc ttatcgttgc ggtaaacgac gacgtcttca cccaactcgc
    12421 cgaaatactg cacgagattg taggtaaagg agtcgtaatt atcgatcatt aagagcatgg
    12481 tgcctgcttg tcgttccgcg gtttcacgcg tgcgtgttca cgctgttatt ccagtccctg
    12541 ctcggcgagt tcgatggctt tcatcatcgc ccgggcctta ttacacgtct cttcatactc
    12601 atgttcagga accgaatcgg cgacaatccc cgcgccggct tgaatgtacg cctgccggcc
    12661 cttgatcacg accgtccgga tattgatgca catgtccata ttgccggaga atccgaaata
    12721 gccgacggct ccggcgtaag gtccccgcct cgtcggttcc aattcttcga tgatctgcat
    12781 cgcgcgaatc ttcggcgcgc cggacacggt gccggccggg aaacaggcac gcgtcacgtc
    12841 gtagacggat ttgccctttt ccaattgtcc ggttacctgc gacacgatgt gcatgacgtg
    12901 agaataccgt tcgacctgca tcaaggaatc caccttcacg gatccgcgag ccgccacccg
    12961 gcccacgtcg ttccggccga gatcaaccag catcacatgt tccgcccgtt ccttttcatc
    13021 cgcgagcaga gaccgagcca ggtcctgatc ttcatcggga gagttgccgc gacgacgcgt
    13081 gcccgctata gggcgcaagg agatctgccc gtcttcgcaa cgaaccagcg tttccggcga
    13141 cgatcccacc aattcgactc cggccacgcg caaataatac atatacggcg aaggattgac
    13201 gacgcgcagc gcgcgataga gctgaaaggg cgtcgtatgg atctgcgtct cccaccgttg
    13261 tgacaggacg gcctggacga tatccccggc gcggatatat tccttggtcc gcgtgaccat
    13321 cttctcaaaa tccgcacgat tcatattggg cgtgaacgtg atgggcttcc ggcggcgctt
    13381 cacccggggc tgccgcaccg gacgcttgag acgggcgatc atcttgtcga tccgcgcggt
    13441 cgcatgtcga taggcctcgc ggacggcgcg atcggtcgtc gattcgagat aggcgttggc
    13501 caccactttg atcttctgcg acacgttgtc gaagatcagc agggtgtcgg tcagcagaaa
    13561 cgccacttcc ggcatcccca ggctgtcttt gcggagggac ggcagctcct caaaggtccg
    13621 caccacgtca taactcaaat acccgactgc gccgccgaca aatcggggca gtccgggcac
    13681 cgtcaccggc cggtactcct ccatcaattc acgcacgcgc tccagcgggt tgccgcggct
    13741 ctgaatcttc aggcgtttct tcccgcgagt cagaatcagg tcgcccttct cttcatggat
    13801 gaccgctgaa gagccgcttc ccaaaaagga atagcgcgcc caattttctc cgccggccac
    13861 actctccagc agataggcgg tcggcccctg gtcgattttg gcaaaggccg acaccggcgt
    13921 ctcgtagtcc gccagaatct cccggtacaa cggaatcagg ttcccttccg ttgccaggcc
    13981 tcgaaattcg tccagggtca gtgaatactg ctgcttggtc atagagatga tccggctgat
    14041 cggttacggc tggctgacga tcagcttttg gcccaccccg acggtgttat ctttcaagtt
    14101 gttccacttg cgcaattgat ccggggcgac atgatatttc tgcccgatgc ggtacaaggt
    14161 ctcacccggt cgcaccgtgt gggtcgtgcc ggtcgccgct gcagccgtcg ctccggcgcc
    14221 atccatcaga tcactgtgag tgagcgcatc cttcgccgcg cccgtggccg gctccaggct
    14281 caagtccgac ggcacctccg tcttgagcgc ctcatccaca gccgccgcaa agtccttctt
    14341 cggcgccgct tttttggcct tcggaatggt cgtcaggcgt ttcatatcct cgtgcgcccg
    14401 cttctccaag aggctggctt ccttcatcgc ctgcgcctct tcctggatct gggccgcttg
    14461 ctgacgaacc gcctcgacct gcgcgcccag ttcgcgattg cgggcttcgt actcgctgag
    14521 ttcccgcttg ccgcgcttca cttccgcatc cagttccgcg ctgcgttttt cttcctgcgc
    14581 gagaagccgc tggaagttga gactgcgcgc cttctccgcc tcatatttct ccgacatgac
    14641 acatccgccc aaacccaggc tgcccaatat cagcagaccg atgggaacta cgctcctgcg
    14701 tctcagccgt ccctgttgtt cactcatcat gtagctcctt cgttcaccct ctcgatggga
    14761 ggcatccatg ccagtcccag ggagaattct atggcgcatg cgctgccgat tcgcagcctg
    14821 agaaagtggg tagaatacgg tccaaggcag cgaaagtcaa agtgaaatgg gcaggcacgg
    14881 tgtttgaccc tctccccgtg cctatgctac cgttcgaaga gcgtatcgtt cttcccattc
    14941 tagcgaacca ccggcacgaa agactatggc atcaggcgca caaccggcct cgtctcgagt
    15001 catttccatc gaaggcatca cgctgcacct ggctcaaccc atgagcatgg gtcaggaatg
    15061 gatcgggagt cgcgagatcc tgaaacagct gctggcctgc tggctggtca tcgacgaacg
    15121 cgacctgccc ctctcgcctc ggattaccgg tcagcccgga atcggaaaaa ccacgctggc
    15181 gatggccgga gcccgtgagc gcaagcagga tctgtatgtg tttcagtgca ccgcggatac
    15241 acgtccggaa gatctcctga ttacgccggt tctggcggaa tccggcacca tcagctatca
    15301 cgcctcgccg ctcgtcacgg cggtcctcac cggcagcatc tgcgtgctgg acgagggcaa
    15361 ccggatgaac gaaaagagct gggcctcgct ggctccgcta ctggatcacc ggcgttgtgt
    15421 ggaatcgatc atcgcaggca ttctgatcaa ggcccatgcg gacttccgct gttgcgtgac
    15481 gatgaacgaa gacgcgtcga cctatgaggt gcccgattat attctgtccc gcctgcagcc
    15541 gaccttaggg atggggtttc ccgcgcggga agacgaactg gcaatcctgc ggtatcacct
    15601 ccccttcgcg ccggcggaga tgttggcgct gaccgtggaa tttctccagg aagcgcacca
    15661 actcagtctc gaatactcgg tccgcgacgg catccatctg ttgcaatacg cgttgaaacg
    15721 gcgcgcgcag gatcctaccg atccgctctc ggtcgacgcg gcctggcggg aatccctcat
    15781 caaggtgctc ggcgaggaag ccctcgacct gccgatgcag tcacgccgtc gaaaacgcgc
    15841 cctcggcgat caggccctgc cgcaaggact cggagatttc ttctttggaa gtgatgaccc
    15901 tctacatccc ggccgataat ggcagcacca tcttccaccg ccgacgacgt cttccgcctc
    15961 tcaccccgca tcgaactgtt tccggtcctt cacggcagcg gtgatgtggc acaggaagtg
    16021 cgcgaccggc tgaccgatcg ccgctatgac tgcctggccg ttcccctgcc gccctctttc
    16081 gaacacccgc ttgaagaagc ggtcgtcgat ctgccgacca tcagcgtgat tgtgcagcag
    16141 gagcccgact cagagaccgg cgcgacggtc aactacgtgc ccgtcgatcc ctgtcaagca
    16201 gtcgtgatgg gaattcgcgt cgcgatcggg gaagggatgt atcgggctta catcgatcgg
    16261 gaaacgtcgg tagtcgaacc aatccccttc gtgtcgcccg acgcctatgc cctcaagcgc
    16321 ctgccctatg ccgccttcgc cgcgtccatg gtaccgacgc tcacgacccc cgcggaggga
    16381 tcacaacagc aggcccgcat cgcctggatg gcctttcagc tccaccagct ggagctggaa
    16441 tatgagcgca tcctctgcct gtgccacttc gccgactggc cctggattcg ccaggcctac
    16501 cagcaacggg ccgactatca cgaaccggat gccgacatac gccgaccgga gcaatacctc
    16561 gtggaaccgg cgtcgctgta cttcgtgtta ggcgagttgc cgtttctgac ggaactgtac
    16621 gaacgccgcc gcgccaccgt ccactcggac cgtcatcttt cgatcgacgg catcaaagaa
    16681 ctgctgatcg aaacacgcgc gcgctggcaa accgcgcatg atgaggaggg acacaccgtc
    16741 cccaattggg tcacgccgca gctgctgcag ctctatctac aatacgtgcg gaaccatgca
    16801 ctgctcgacc gccgcctgac gccggacttg tacacgttgg tgctcgccgc caaacagatg
    16861 gccggcgacg actttgcgat tcgcctcctc gaaacggcca agagttacgc ttatcaggag
    16921 atcgaaggca aacatctgcc gcagctttcc gccggactgg gccaattcgc cctgccggat
    16981 gagcagatcg ttcgggcgac gaaccggctc cagggcgcac cggtgacctg gcgctcgctg
    17041 tcgctccgcc cgcgtccgcc gcgcaggacc agccagcggt ggtcctatct ctggaatccg
    17101 aatcggcaat gttcctggcc gccggaagac tccaagatcg aaagttttca cacgcacgtc
    17161 cgcgatcaag ccaaagcgat catcggcgca gacctggcca agagcgaaaa gtttacgacc
    17221 tcgatgaaag acggcatcga cattcgggaa agtttgcgcc actggcacca acgcgccaag
    17281 ccagggcgcc cgaaccggct ggaactctac gtcaaagaaa tccctccggc acgcgggaat
    17341 gtcgataccg tgattttcct cttcgatacg ccggccgatc ccgatcagta cagctggcag
    17401 gccacctggt atgccgaaca tgcgcaggaa tccacactct gtttttatgc cacgccgttc
    17461 ttgaacaaca tgattgcccc cggcatcggg caatcactct acggcggcgc tctgttcatc
    17521 tttccacctc gcccgatacc tgacatctgg acggatgagg cgctggggtt tgcgacaacg
    17581 ctcgaggaac gtttgatcgc cgccggagct gcccattcac atgagacaca cgtggccctg
    17641 gtgacgccgg ttcctcccaa ggcgcggtgg cggcagatcg cctcacggtc tggacggcgc
    17701 ctggtgccga ttccgttgag tcgcttttcg ggacagttga ttgaccggtt acggcgattc
    17761 catgtgctga acggacaaga tatccgcagc ttcgccgcgc agttcattcg tgagtaatcc
    17821 acccatggcc gaccgcagca ttgaacaacg gatcacggcg ctccgccgcg agatccggca
    17881 tcacgaccat ctctattaca cgaaagatcg tcccgagatt tccgatgccg aatatgaccg
    17941 cctctttcgt gaactcgtcg atctggaaac cgcgcatcct gatctgatca ccgcagactc
    18001 gcccacccaa cgggtcgggg cgccgccttt gagtgagctc accaaggtgt cgcacgagaa
    18061 accgatgctg agcctggatt cgatcgtcga tcaggaggat gtccgcgcct tcgaccagcg
    18121 catgaaacgc gagctggaaa ccgaccagcc ggtctacaca gccgaaccga agttcgacgg
    18181 cctgtcagtg gaactggtct acgatcaggg ccgcttcgtg cgcggcgcga cgcgtgggga
    18241 cggcatgatc ggtgaagatg tcacggtcaa tctccgcacg atccgctcgc tgcccttgca
    18301 acttcatgcc gaaacgggtc caccggcgca tctggtggtc cgcggcgaag tctacatgcg
    18361 gctggatgag tttcagtctc tcaatcggcg gatgacggag cgcggcgaag aaggctttgc
    18421 caatccgcgc aatgcggcgg cgggatcatt gcggcagctc gatagccgca tcaccgcctc
    18481 ccgtcccttg accgtcacct gttacgacat catggccatc gccggcccga tgcccgccac
    18541 acattgggac gagttggaag cgctcgccgc ctggggcttg ccggttccgg aacatcggca
    18601 gcgttgccgg tccatcgacg aggtcctcac gttccaccag acgaccgacg cgatgcggga
    18661 cgaccttccg tttgagatcg acggcgtcgt ggtcaaactg gatcgccgtg attggcagga
    18721 tcaactcggc agcaaatcgc gcagtccccg ctgggccatt gcctacaagt ttgccccgag
    18781 gaaggaaatc acggtcattc aggatatcgc ggtctccgtg ggccggaccg gcacgttgac
    18841 gccgttggcg ctgctcaaac ccgtagaggt gggcggagtc accatcagcc gcgcgacgct
    18901 gcacaatgcc gacgaagtgg cgcgtaaaga cgtgcgcgtc ggcgatacgg tcaaggtgga
    18961 gcgagccggc gatgtgattc cggcaatcgc cgagcgggtg cccgtcccgg gtgaggagcg
    19021 gcaggcgccg ttcgtcatgc ccgaccattg tcccgtctgc ggttcggcgg tggcgcgcga
    19081 aggcgcttac ttttactgca cgggacagac cgtctgtatg gcgcaactca aaggtgcgat
    19141 cgaacacttc gcctcgaaga gcgcgctgaa tatcgacggg ctggggaaga aaacggtggc
    19201 ccagctggtt gatgcaggaa tggtcaaaga cctcgcggat ctgtacagcc tgacaaaaga
    19261 acaactgttg accctggagg gcttcgccga ccgatcggcc agcctgctca tggactccat
    19321 cgagcgaagc aaggccgtct cactggagcg tttgttaatg ggattaggga ttcggcaggt
    19381 ggggcaacac attgcacgcg tgctggcgaa gcatttcggc acactccccc gagtgatgga
    19441 agcgacgcag gacgagttgc tgcacgtgcg ggaaattggt ccggagatct cagagagcct
    19501 ggcctcgttc ttcaccgaag cgcgaaatcg ggaagtgatc gagcgcctcg tcgcccgggg
    19561 attgacggtc gctccgccgg tggcggaagc cagtccaggc ggccggaccc tgaccggcaa
    19621 aaccttcgtg tttaccggtg gcctcgctgc ctacagtcgc gatcaggcca aagaactggt
    19681 cgaacggcag ggaggacaag tgtcgtcgag tgtgagtaag aaaacggcgt atgtcgtggc
    19741 gggaatcgac cccggatcga aactcgatca ggcgcagaag ctcggcgtga agattctgac
    19801 ggaagcggag tttaccgatc tggtgacgcc tgggtgaccg gcacatgctc ctcgaccggc
    19861 tggtccggca acgcggggtg tttgtcttcc ttgtagatct ggacgctttt aatcacccgc
    19921 ggatccgctt catggatcac gagccggcag ttggcgatat gcacttcctc gccgaccttg
    19981 ggaatccggc cgagttcgtg ttgcaccagt ccgctgatcg tcacggcatc gtcccccaag
    20041 tcgaccttca agaagtcgtt gaccttccgc acttcggtgc ggccgtgcac caggatctgg
    20101 ttcttgccga tccgtttgat caattcttcg gtgatgtccg tctcatcgac gatttcgccg
    20161 accacttcct cgagcaaatc ctccaacgtg accagaccca taacgccgcc gaattcgttc
    20221 acgacgatcg ccatgtggcg tttatccaac tggaactgtt tcatcaaatc gtcggccgat
    20281 ttcgtgtgcg ggataaacaa cgccggctgt gcgatatccc gcaacttcat ttcggtatgg
    20341 ccctgggcca gggcggtcaa cgccttggtc ttgtagagga tgccgataat gttatccagc
    20401 gtgccttcgt acagcggaat gcgcgagtac ttcgacttga acaacagctc cttcgcttcg
    20461 cgcaggtatt gattgcagtc gagcgagaac atgtagatgc gcggggtcat gcagtcttcc
    20521 gccgtaatgt ccttcagctg gaagacgttc ttgatcatct tcacttcctg ggcctcgatg
    20581 gcgccgctct tgctgctctg gtccagcatg atcttgagct cttcttccgt gacgaagggc
    20641 acattgagcc ccttcccgcc ggtaagcttg tagatcaacg gcacgacgaa gaacatgatc
    20701 ggcgtgagca cctgctgtgc tgcataggcg ggatatgcca tgttcagcac gacgggaaca
    20761 gaatatttcg ccgcaagggt cttggggacg agatcggcga acaccagcaa cacaaatgtc
    20821 aggataccga cgagcaccgc aaaggcctcg ccgagtacac cttcaagccc ctgccctccg
    20881 aaccggttca aggcaatgat cgtggccaac gacgcggtcg ccgtatcgac cagccggtcg
    20941 ccgaccagaa tggtcaacag gagccgttgc ggatcggtgc gcagatgcag ggccatctct
    21001 gcccgcttgc tgcccgtatc ggccaaggcg cggagtttcg tgtcgttgac ggaatagaag
    21061 cccacttcga cgacggagat gaccgccgac aacagaataa ggaagatcaa gacgataatg
    21121 tccataagac ctatcgaggc taaaggtacg gaacaacaat gtcagggtaa aaaatggatc
    21181 tttggatcag ttcgaagcct acggttcgaa ctgcaaggct cgcccgatgt cgtgagaaga
    21241 cgacgagaaa aggtcctctc gggtcaccat catccattac ctattacact tagcataggc
    21301 cgagagtcgc atcaagcctt gagaggaaat cttgctgcgg acaatgcatc acgatatcaa
    21361 ccgtttaaaa tatttacccg ccacaacact catggatttc ccgtagcggg cgactcactg
    21421 tcgtcccgca caatgaacgg atccgtatcc agggctcgtt tcaaatgtgc ggcggcctgt
    21481 tcggcgtcgg cttccgtgcg aaattggccg gcatagacac gataacgtcg cccgtccggc
    21541 agatcgaccg ccaccgctcg agaaccggga tacgcattcc gtagccgctg cactagagcc
    21601 tgcgcgttgg acgggtcggc aaaggagccg acctgcactc gcaaccagcc catctctcct
    21661 gccctgccct gatagctgat aacacgcagt tcaatctcgt ccgtgccccg gccgaccata
    21721 cccaccgcct gggcaccggc cagcgagagg tccagaatcc ttccccgcgc gaatggcccg
    21781 cgatcattga tgcgcacggt tacctgccgt cccgtcgtca acgagcgcac taccgccacc
    21841 gaacccaggg gcaatgtccg gtgcgccgcc gtgagtttat gcatgtcgta gacttcgccg
    21901 ttggccgtgc gattgccgtg aaagccaggc ccgtaccagg acgcgcttcc acgctccacg
    21961 aatcccaagg gataccctgg cggataggac gggcgcgccg gactccagcc ggagcagcca
    22021 tggagccatg tagtcaggag cagagcaaac agggggagaa gaagacggct tgtgctggtc
    22081 ctcttctctc ccggcgtgag gcggattcgc aggatgctga aaaagagact caacccgcta
    22141 aaattcgtcg agtgaatggg tgcgcagcac cccgagggct ttggtggtgt tcgaca
//
LOCUS       DAOQPD010000063        21911 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1141_length_21911_cov_24.809709, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000063 DAOQPD010000000
VERSION     DAOQPD010000063.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 21911)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 21911)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21911
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1141_length_21911_cov_24.809709"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..997)
                     /gene="aroF"
                     /locus_tag="PK063_13655"
     CDS             complement(<1..997)
                     /gene="aroF"
                     /locus_tag="PK063_13655"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HMZ98143.1"
                     /translation="MIIVLKPDASEREVDHITDRLRELGLKSHISAGQERTIIGVIGD
                     DRILHNQPLTALPGVESVLPILAPWKLVSREFKKENTIIDVNGVKIGDKKITIMAGPC
                     AVERLELTVGIAHEVKSAGATVLRGGAYKPRTSPYSFQGLGREGLDYLVEAKKQTGLP
                     VVSEILDTRDIELFLEKADIIQIGARNMQNFELLKEVGAYDKPVLLKRGLSATIKEFL
                     LSAEYVMSRGNRNVMLCERGIRTFETQYRNTLDLAAIPTLKDLSHLPVIVDPSHATGK
                     WDLVAPMSKAAIAAGADGLLIEVHSNPECALCDGEESIRPSKFKELMGDLRKIAAA"
     gene            complement(1016..2101)
                     /gene="hisC"
                     /locus_tag="PK063_13660"
     CDS             complement(1016..2101)
                     /gene="hisC"
                     /locus_tag="PK063_13660"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HMZ98144.1"
                     /translation="MPLKVHPDIVSLVPYVPGKPIEELQREMGLPRVVKLASNENPIG
                     PSPKAMAVLAETVPTLHRYPDGGAFRLRGALAERWKVAPDQVILGNGSDEILGLLART
                     FLSPGDEAVMAEHTFVIYKMEVQAAHGVAVEVPQKNWHHDLPAMAAAITEKTRLLFVC
                     NPNNPTGTMATKAEVAALMERVPDHVVVVFDEAYYEYVRHSEFPESLAYVKAGRPVIV
                     LRTFSKIYGLAGLRIGYGITTPEITNYLNRIRPPFNANSMAQRAALAALDDDAHVAAS
                     RSLNHVEMDKVRAGLRRLGFEALPSETNFLYFDVGRNGRAVFDALLAKGIIVRHIEGR
                     MLRVTIGLPDENQLFLSALEDVTRASQ"
     gene            complement(2118..3194)
                     /gene="pheA"
                     /locus_tag="PK063_13665"
     CDS             complement(2118..3194)
                     /gene="pheA"
                     /locus_tag="PK063_13665"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HMZ98145.1"
                     /translation="MSDDLQVHREEIDRVDDQILRLLNERSKSVIEIGRLKKLKDADA
                     NLHTQARESAIFDRLSKQNTGPFPTEAIRAVYREIMSASLSLEGPQKVAYLGPRATFT
                     HMACMQKFGASAQYIPVNSIKDVFSEVERGRAHFGVVPIENTTEGVVNHTLDMFVDSN
                     LLIYGEVLQEVAHHLMSKSGLAGDIKRIYSHPHAIAQCRNWLETNLPHVPVSEVASTA
                     RAAEMSVDDPSAAAIASELASQLYGLKVVTARIEDNINNFTRFLVLSQKAPERTGRDK
                     TSLMLSVKDKVGALYDLLRPFASHGLNMTKIESRPSRRKAWEYIFFVDIEGHIDEERV
                     KKAAEEVKSRCLFMKILGSYPAYS"
     gene            complement(3334..4371)
                     /gene="ruvB"
                     /locus_tag="PK063_13670"
     CDS             complement(3334..4371)
                     /gene="ruvB"
                     /locus_tag="PK063_13670"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HMZ98146.1"
                     /translation="MADRTVSNQLTDDERGLEAALRPQSLREYVGQPRMKESLEICIE
                     AAKRRGEALDHAIFYGPPGLGKTTIAHIIAREMGSAIRSTSGLVLSHAGDLAAILTNL
                     QERDVLFIDEIHRLPASVEEALYPAMEDYQLDLVVGQGASTRTVKLELPHFTLVGATT
                     RAGALTSPLRDRFGLVHRLEFYSSQELTSIVTRSAGLLNIPIDEAGAAEIARRARGTP
                     RIVNRLIKRIRDYAEIKAGGRITQRVAQDALVWLAVDEAGLDEMDRRVLLTVIEKFHG
                     GPVGVDSLAAAVQEDKGTLEDVYEPYLIQAGFLERTGRGRQATRLAYEHFKKQKDLLP
                     FSSETDSIATP"
     gene            complement(4911..5519)
                     /gene="ruvA"
                     /locus_tag="PK063_13675"
     CDS             complement(4911..5519)
                     /gene="ruvA"
                     /locus_tag="PK063_13675"
                     /inference="COORDINATES: protein motif:HMM:NF001040.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HMZ98147.1"
                     /translation="MIALLTGLVAFKAPSQVTLDVHGVGYEVLVPLSTYYSLPNQHEP
                     VTLSIHTHVREDAIQLFGFFTASEKEAFLLLTGISGIGPKLGLSVLSTLSVRDLYAAI
                     QAGDIEKLGTVPGIGKKSAARIALELKDKVAKLHPSGDLGVAGSGRSDNPLYEDALSA
                     LVNLGYRQPDVKEALKRVEQSGVLTQGLEQVIREALKDLAKG"
     gene            complement(5601..6356)
                     /locus_tag="PK063_13680"
     CDS             complement(5601..6356)
                     /locus_tag="PK063_13680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HMZ98148.1"
                     /translation="MGGHSHWATIKRHKSAVDAKRGKVFTRIIRELTIAARSGGDPDG
                     NPRLRLAIAKAKEANMPGDTMKKAIQRGTGELPGVTYEEFTLEGYGPGGTAVLMEITS
                     DNRNRTVAEIRSLLTKNGGNMAEAGAVAWQFHKKGVLVVEKGKVEEDALLTIALEAGA
                     EDVKVSDKAFEVLTSPHDFEAVKKALSDAKIEYTLAELNFIPQNTIALEEKAAEQMLK
                     LMEILDEHDDVQKVHANFDISDEVMEKVAAATA"
     gene            complement(6500..7207)
                     /locus_tag="PK063_13685"
     CDS             complement(6500..7207)
                     /locus_tag="PK063_13685"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98149.1"
                     /translation="MVLASTGSFSIAESDDHGHSSTENHGHHHESSPSASQWEGSREG
                     IAYSEFNHHLAGVFLLLIGLSELRQALGWPVLTWTRFLLPGALAVAGLFLLIWSDHDA
                     WPIGSMTFAETFFGKDPEVLQHKTYGVLALAVGTIEFLRRLGRSATAVWTAPLPIFAV
                     VGGFMLFSHSHGDHPAADKIALHHLMMGTMAIIAGSSKLISGWRQRQLATERSYWELV
                     WAILVLVIGVQLLFYSE"
     gene            complement(7354..8109)
                     /locus_tag="PK063_13690"
     CDS             complement(7354..8109)
                     /locus_tag="PK063_13690"
                     /inference="COORDINATES: protein motif:HMM:NF019968.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PCP reductase family protein"
                     /protein_id="HMZ98150.1"
                     /translation="MKFVCLNCETYMTFQKVEKPGEGSLGVFFGCPSCEAKFSMVTNP
                     GETQMVASLGVKLGGRTETAEPFEMTRGTLKDEAQAGAGQMAAYLNEKIQGGQPATAA
                     PKATAPAAGGEKTSGGCPFSAMVAEMGLTSGGKPQNGNGTSEFTWTADAKEKLERLPS
                     FVKPMVQSSVEAYARKHGYKSITLQVMDDSKNDSPNGIAWTKDAEQRMDNIPDFIRPM
                     ARREIERIAKERGLVEITAQVMDEAKEKFMKFM"
     gene            complement(8136..9062)
                     /locus_tag="PK063_13695"
     CDS             complement(8136..9062)
                     /locus_tag="PK063_13695"
                     /inference="COORDINATES: protein motif:HMM:NF022077.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HMZ98151.1"
                     /translation="MTMAAGKDLKSILTKLQYSDDAKVVQQITAQMKQVQARMAGIKQ
                     KLVVMSGKGGVGKSMTTVNLALAFARQGAKVGLLDVDLNGPCVPRMMGLHGQSLTMTP
                     EGAQPPVGPLGIKVASMDFFLGDASPVRWKGPMDLSPVWLGLMEMNVIREFLADVVWG
                     ELDYLLADLPPGAAADKPPVIAGFIPDLAGAIVVTTPSEVASDVVQKSVTYARDMGIR
                     VLGIVENMSEYRCPSCGAENELFEGNTEAMCEVLDLPLLGRIPFDRTLAKTFDKGQPL
                     LDPDYPTIRKYQEIVGRIQSLLDYKKVLAEKL"
     gene            complement(9141..10988)
                     /locus_tag="PK063_13700"
     CDS             complement(9141..10988)
                     /locus_tag="PK063_13700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HMZ98152.1"
                     /translation="MTQHDQTKPQESLNIVIVGHVDHGKSTLVGRLYADTGSLPEGKL
                     EKVQAICRQQGKEFEYAFLFDAFLEEQEQGITIDTARTFFIWNGRQYIIIDAPGHKEF
                     LKNMISGAARAEAALLLIDALEGVREQSKKHGYLLSLLGVTQFAVVVNKMDLVGYRQD
                     VFDGIEKEYREFLGQFRAVPQQMIPVSAKMGDNIATRSTHMNWYQGPTVLETLALFKK
                     EQVRSEQPLRFPLQDVYKFDARRILAGRITAGRLKVGDQLVFSPSNKTAVVQSIEGFN
                     VDPPPSEAQAGQSVGITLDEQIFVERGEIASHRDSVPLVSTAVRVNLFWMGRRPLEKG
                     RKYVLRLATREVACEVAVIHRIIDTADLAQLQESQSVARNQVAELTLRVKSPLAFDLS
                     SSFESTGRFVLVDEYDISGGGIITELVHDEQEGLREEARQREYAWLTGDVRPEDRALQ
                     YGHRAAIVLFTGSAQTGKTFLARRVEALLVADSRHAYLLEGENLLQGLDADLSAADPS
                     FASERVRRYGEVARLLIDTGLIVVSTSKTFGINYQRMAEMIRTLVQPAPVIAVHMSRA
                     GEEPPPNTDLHFAGPQDFDAAARQIIEELKKRGVLIQPSGTKSNIQYSI"
     gene            complement(11063..11860)
                     /gene="cysD"
                     /locus_tag="PK063_13705"
     CDS             complement(11063..11860)
                     /gene="cysD"
                     /locus_tag="PK063_13705"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009336 - sulfate adenylyltransferase
                     complex (ATP) [Evidence IEA];
                     GO_function: GO:0004781 - sulfate adenylyltransferase
                     (ATP) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0019419 - sulfate reduction [Evidence IEA];
                     GO_process: GO:0070814 - hydrogen sulfide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="HMZ98153.1"
                     /translation="MKHLRQLEDQSVYILREAYKHFNHLAMLWSMGKDSTVLLWLARK
                     AFFGHVPFPLLHVDTSYKIPAMIEYRDRIAREWRLNLVVGQNKEALAAGMNHTLGRDV
                     CCTALKTNAMKNLVEEKGYTGIILGVRADEDSTRAKERYFSPRDKHGDWDFRDQPPEL
                     WDQFKTTFPPGTHIRIHPLLDWTEINIWEYIKHENIPFMDLYLDRGDGTRYRSLGCAP
                     CTMPIKSTAKTVDEIIVELRKSTVAERAGRAQDAGRGMEMLRKKGYM"
     gene            complement(11878..12945)
                     /locus_tag="PK063_13710"
     CDS             complement(11878..12945)
                     /locus_tag="PK063_13710"
                     /inference="COORDINATES: protein motif:HMM:NF012800.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HMZ98154.1"
                     /translation="MQHLLAKVAKGQKTSKDLTWEEAKQAMRLMIEGTATQAQIGAFL
                     TAMRFKSESVTELAAFTATARQYVPPVPVRSGLGVVDVPVYAGKRETFHAIVPAAIIA
                     AAAGAVVLLHGVDGPADRRGVSSVLKLLGIPTDQTAKLVGPELEKKGFAYLDLALYHP
                     PVSRFLEMRQELGVRNFFHPVARMLNPARAASQVIGLSHPPYFEKTIEALRMLSCPRA
                     LVIRGVEGDPELSIGNSTRLLELKDERITPFTFQPKDAGLAMATFREMAGFPAEQRER
                     EADLIKRLVANEIQGGQRDWVLLNAAMLLYAAGKGTSITGNLAAARNALESGRAKAKL
                     SELIAGPGSETAAGSKVGLSA"
     gene            complement(12988..13710)
                     /locus_tag="PK063_13715"
     CDS             complement(12988..13710)
                     /locus_tag="PK063_13715"
                     /EC_number="1.8.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0004604 - phosphoadenylyl-sulfate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0019379 - sulfate assimilation,
                     phosphoadenylyl sulfate reduction by
                     phosphoadenylyl-sulfate reductase (thioredoxin) [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenylyl-sulfate reductase"
                     /protein_id="HMZ98155.1"
                     /translation="MQDTQKSAERPSDAELKALSDSFESQQPWDLLAYALKTYQGRIV
                     LACSFGAEDVALVDMVHRIDPDAPLFYLDTDFLFPETFDVRDRIVARYGLKPAQVIQM
                     KSLLTPEQQAAQHGAALWASKPDQCCELRKIEPLTRILGQYSAWITGIRRDQAPTRAN
                     AGLIEWDKKFQLVKVNPLAAWSTEQVWTYIQLHEVPYNILHDRNYPSIGCTHCTAPVL
                     PGDDPRSGRWKNFGKTECGLHK"
     gene            complement(13717..16203)
                     /locus_tag="PK063_13720"
     CDS             complement(13717..16203)
                     /locus_tag="PK063_13720"
                     /inference="COORDINATES: protein motif:HMM:NF013259.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA family protein"
                     /protein_id="HMZ98156.1"
                     /translation="MISSHTEALRPAVKTEPIPPHIVEEIETFEAEAQRVLAGDLSTD
                     IFKPFRLQYGIYGQRQPGVQMFRIKIPFGGLTANQLRRVAELADQFATGVGHVTTRQD
                     IQLHFVELKHVPEMMRQLAAVGLTTREACANTVRNVTACHLAGVCQGEVFDVTPYAKT
                     VAYHLLRNPLNQSLPRKFKIALSGCRQDCALTPIHDIGLLAAKRADGTIGFRMVAGGG
                     LGSTPRMAQVLREFTPMDELLPTIEAVIKVFDTLGNRKNRNKARMKFVIEKLGFDEFK
                     RRWEAAYAAMGYAVPTHEPIKLLEYADTPPLLMPTKAPNSTNGNGNGNGNGAASRNGA
                     ESAFEAWKRTNVVPQRQAGFAAAAIKLPMGDLTGEQMWVVADLAERYSNGNIRTTINQ
                     NVIIRWIQEDRLSAFHEELVAHSLGDPGAELVEDIIACPGTDTCGLGITSSKGMARAL
                     AEVFPAGQVPEDLRDVSVKISGCHNSCAQHHIATIGLHGVGKRLGEHTAPHYELHLGG
                     HVDGTPKIGQLAVKLPAKSVPAAVRHLVDVYRRDRKPGESLQTFIGRVGKNVLKDELI
                     PYTIVPAYDQDPTYYYDWEGEAEFVLEDLGPGECAGGALEMIDDRMLEADQELYQAKL
                     LVEKHQYALSVNKSYRAVLAAAKGLLVTEGIDPATDAETFQEFDVRLASKGIVPASYT
                     NLGAQVGDLGSKDATAETANDKMAFAKRFLSVCRAATEQMGKDLKLAQVKEEVVPTPA
                     PKVEPASPVATAPVYDLRGVACPMNYVKTKLKLEMMDNGEQLEVWLDAGEPIRNVPMS
                     LRNDGHKILEEGPLEPEAKHFKILVEKVEG"
     gene            complement(16252..16704)
                     /locus_tag="PK063_13725"
     CDS             complement(16252..16704)
                     /locus_tag="PK063_13725"
                     /inference="COORDINATES: protein motif:HMM:TIGR00738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HMZ98157.1"
                     /translation="MKVSLRATYGIIAAVDLALHHAEHPVCAKSIAKRQAIPARFLEQ
                     VLHAMKKAGVVTSQRGAQGGYVLSRKPSELSVADILDALEGPLLSTNGDAAPKQTSSR
                     ASKQEALLAHIWDRVKRAELSVLSEVTVEELAKRQRALDEQHTLMYHI"
     gene            16719..17066
                     /locus_tag="PK063_13730"
     CDS             16719..17066
                     /locus_tag="PK063_13730"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98158.1"
                     /translation="MGIHECLYIEPRFPVKPAGAGLVADIADALAAITLADNCSPSLG
                     RDEFAASKVSNLHCELMPPTISSTSAHFLHFDRSGCINTGADFLIDIIWGLSNNPALF
                     FLGASHDAAFINI"
     gene            17041..17625
                     /locus_tag="PK063_13735"
     CDS             17041..17625
                     /locus_tag="PK063_13735"
                     /inference="COORDINATES: protein motif:HMM:NF014950.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HMZ98159.1"
                     /translation="MTLRSSTFNILLLSTDSEIQSHYKDLFGEQAITVGREGPSLQKD
                     LAKRDYDAVIIESKLAAAADLSKLLTGIDPSRTLLLVGSRTVLKRTAAVLQASKASKA
                     EAPPSNGKGQALCLDSYLEHKVGDFVKGMRNGSGKNLHPMLIAAVERPLILLTLRETK
                     GNQIQAAELLGLNRNTLRKKILDLDIPVKRARAS"
     gene            17594..17989
                     /locus_tag="PK063_13740"
     CDS             17594..17989
                     /locus_tag="PK063_13740"
                     /inference="COORDINATES: protein motif:HMM:NF037081.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HMZ98160.1"
                     /translation="MSPSNAPGPASVPTTEPHLTRRHKYAHASHPRVANHQRREAMTK
                     EELIAQMANSAGITKVAATVALEAFTGAVTTSLKKGKRVTLVNFGTFTISKRKARMGR
                     NPRTGEALKIPAARIPKFSAGKELKAAVK"
     gene            18121..18195
                     /locus_tag="PK063_13745"
     tRNA            18121..18195
                     /locus_tag="PK063_13745"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18153..18155,aa:Val,seq:gac)
     gene            18283..20238
                     /gene="thrS"
                     /locus_tag="PK063_13750"
     CDS             18283..20238
                     /gene="thrS"
                     /locus_tag="PK063_13750"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HMZ98161.1"
                     /translation="MASQLIHITLPDGTRKQVPTGCTVREALTPQGGRLDGKILAAKV
                     NGVPMDLFHALDQDASVEPLTFESAEGREVYRHSSTHIMAQAVKEVFPSAQLTIGPAL
                     DDGFYYDFAFDRPFTPEDLEKIEARAIEITKRGLTVSRSELSKEDAIKFFQDRGEAYK
                     VELINSFDDGSPISLYRQGEFVDLCRGPHLPTTGYVGAFKLLSTGGAYWRGDERNPML
                     QRVYGTSFPTKKELDAHLAKLEEIKRRDHRKLGKELDLITIQDDIGPGLVLWHPKGSL
                     IRLLIENFWREQHIKDGYDLVYSPHVARLDLWKTSGHVDYYRENMFASMKLEGSEYQL
                     KPMNCPFHIMIYKSHLRSYRDLPIRYGELGTVYRYERTGVLHGLLRVRGFTQDDAHLF
                     CRPDQIEAEVSRVLDFTFFVLGTFGFTEFEIYLSTRPEKSVGSDENWTIATNALEAAL
                     KSRNVAYQVDPGEGVFYGPKIDIKIKDVLGRSWQCSTVQVDFNNPERFKLAYTGEDGK
                     HHQPIMIHRALMGSIERFFGILIEHYAGAFPTWLAPVQAVVLTITDHQQEFAAKIVST
                     LKSHGYRVEADLRNEKIGFKIREAEKNKIPYMLVVGDKEVQSGMVAVRGRSKADHGTM
                     PIEQFLELIRTDTNQSLRDTATHSQTR"
     gene            20242..20748
                     /gene="infC"
                     /locus_tag="PK063_13755"
     CDS             20242..20748
                     /gene="infC"
                     /locus_tag="PK063_13755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HMZ98162.1"
                     /translation="MVPKLRVNREIRIREVRVIGPDGEQLGILPTVEAFNKAQEGGYD
                     LVEVAPTSQPPVCRIMDYGKYKFELSKKDHQSRRHQKSTQVKEIKLRPRTDKHDLEIK
                     IRQIKEFLADGNKTKVTLTYRGREMANQEMGRTMMTSVIQQCMEAGTVEFAPRMEGRS
                     LIMILAPK"
     gene            20782..20979
                     /gene="rpmI"
                     /locus_tag="PK063_13760"
     CDS             20782..20979
                     /gene="rpmI"
                     /locus_tag="PK063_13760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HMZ98163.1"
                     /translation="MKQKMKTHSGAKKRFRRTGTGKLVRRKAGGRHLLTGKPRDRKRN
                     LKGATEVSSASTPALNKLLPQ"
     gene            21023..21391
                     /gene="rplT"
                     /locus_tag="PK063_13765"
     CDS             21023..21391
                     /gene="rplT"
                     /locus_tag="PK063_13765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HMZ98164.1"
                     /translation="MPRTKGGPKTRQRRKKRLKLAKGQYGAKSRLFRTATESVDKGQA
                     YAYSGRKQRKRDFRQLWIARISAATRLHGIAYSRFMNALKKANILLDRKVLSDMAIRD
                     MAGFEKLVGVAKQQLATAAS"
     gene            complement(21447..>21911)
                     /locus_tag="PK063_13770"
     CDS             complement(21447..>21911)
                     /locus_tag="PK063_13770"
                     /inference="COORDINATES: protein motif:HMM:NF036799.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98165.1"
                     /translation="EWANVVEVDNVMSLSYSCLRQWITPSLLQVETNSSRAFYPHRMF
                     EVGEVAVPDARADVGSRTITMLGAVIAHAGAHFSEIHSCLDLLLYYLDRPFRLEPVPH
                     PSFLEGRAGRIMLDGRAIGLLGELHPEVLEQWQIGVPAVALELEIDRLLDEA"
BASE COUNT         4743 a         6568 c         5905 g         4695 t
ORIGIN      
        1 cggcagcagc gatcttgcgc aagtctccca tcagttcttt aaatttcgac ggccggatcg
       61 attcctctcc gtcacacagc gcgcattcag gattggaatg gacttcgatc aatagcccat
      121 cggctccggc agcgatcgcg gctttggaca tcggcgctac caaatcccat ttgccggtgg
      181 catggctggg atcaacgatg accgggagat gggaaagatc tttgagcgtc gggatggccg
      241 caaggtccag cgtgttccga tattgcgttt caaaggtgcg gatgccccgc tcgcataaca
      301 tgacattccg attgccgcgg gacatgacgt actccgcgga aagcagaaac tccttgatgg
      361 tggccgagag cccgcgcttc aacagaaccg gcttatcgta cgcgcccact tccttgagca
      421 actcgaagtt ctgcatgttg cgggcgccga tttgaatgat gtcggctttt tccagaaaga
      481 gctcgatatc gcgagtgtcg aggatctcgc tgacgaccgg cagaccggtc tgcttcttcg
      541 cctccaccaa ataatccaac ccctcgcgtc ccaatccctg gaaggaatag ggtgaggtac
      601 gcggcttata cgccccgcct cgcaacaccg ttgcgccggc ggatttgact tcgtgcgcaa
      661 tacccacggt taattccaag cgctcgaccg cgcagggacc ggccatgatc gtaattttct
      721 tatccccgat cttgaccccg ttcacatcga tgatggtgtt ttctttctta aactcccggc
      781 tgacgagttt ccatggagcc agaatcggca acacgctttc cacaccgggc aaggcggtca
      841 acggctgatt gtgcaagatc cggtcgtctc cgatcacccc gataatcgtg cgttcctgtc
      901 ctgccgagat gtgggacttc agccccagtt cccgaagccg gtcggtgatg tgatcgactt
      961 cccgctccga agcatcaggc ttcaagacaa taatcatggt ctcgtctcgc tttccttatt
     1021 gcgacgcgcg tgtgacgtct tccagcgcgc tcaggaacaa ttgattttca tccgggaggc
     1081 caatggtcac cctcaacatg cggccctcga tgtgacgcac aatgatgccc ttggccaaca
     1141 acgcgtcaaa gactgcgcgg ccgtttctcc cgacatcgaa atagagaaaa ttcgtttcac
     1201 tgggcaaggc ctcgaacccc agccggcgca gaccggcacg caccttgtcc atttccacgt
     1261 gattgagtga gcggcttgcc gccacatgag cgtcgtcgtc cagcgccgcc aaggcagcgc
     1321 gctgcgccat actgttggca ttgaagggtg gacggattcg attcaggtaa ttggtgattt
     1381 caggggtggt gatgccatac ccgatgcgta aaccggctaa tccataaatc ttggaaaagg
     1441 tccgcaagac gatgacgggt cgtccggcct tgacgtaggc gagtgattcc ggaaattccg
     1501 aatgccgcac gtattcgtaa taggcctcat cgaacacgac tacgacatgg tcgggcaccc
     1561 gctccatgag ggcagctact tccgccttgg tcgccatggt gccggtcgga ttgttgggat
     1621 tgcagacaaa cagcaatcgc gtcttctcgg taatggcagc ggccatggcc ggcaaatcgt
     1681 gatgccagtt tttctgcggc acctccaccg ccacaccgtg ggccgcctgg acctccattt
     1741 tataaatcac gaaggtatgc tcggccatca cggcctcgtc tcccggcgac aggaaggttc
     1801 gtgcgaggag gccgagaatt tcgtcggagc cgtttccgag aatgacctgg tcgggtgcca
     1861 ctttccagcg ctcggctaag gccccacgca ggcggaacgc tccgccgtct ggataccggt
     1921 gcagggtcgg aaccgtctcg gccagcactg ccatggcctt aggcgacggg ccgatcggat
     1981 tttcgtttga cgccagcttg accacgcgcg gcaatcccat ctctcgctgt agttcttcga
     2041 tgggttttcc tggcacgtac ggcacgaggg agacgatgtc agggtgcacc ttcaatggca
     2101 tggtgtaact cggccctcta ggaataggca ggatacgacc cgagaatctt catgaacagg
     2161 cagcggctct tgacctcttc tgccgctttt ttgacccgtt cctcgtcgat atgcccttcg
     2221 atatccacaa agaaaatgta ttcccaggct ttgcgacgcg agggacgcga ttcgatctta
     2281 gtcatgttca ggccatggga ggcaaagggt cgcaataaat cgtacagggc gccgactttg
     2341 tccttgaccg ataacatcag cgatgttttg tcccggcccg ttcgctccgg cgccttttgt
     2401 gacaacacca aaaaccgcgt gaagttattg atattgtctt cgatcctcgc cgtgacgacc
     2461 tttaagccat aaagttggga tgccaattcc gacgcaatcg cggcagccga aggatcatca
     2521 accgacattt ctgcggcccg cgcggtactg gccacttccg acaccggcac gtgcggcaag
     2581 ttcgtctcca gccaatttcg gcattgcgcg atggcatggg ggtgcgaata gatacgtttg
     2641 atatctcccg ccagtccgct ttttgacatc agatgatgcg cgacttcctg caggacttcg
     2701 ccgtagatca gcaggttgga atcgacgaac atgtcgaggg tgtgattcac cacgccttcc
     2761 gtcgtgttct cgatcggcac gacgccgaaa tgggcgcgtc cgcgctccac ttcgctgaag
     2821 acgtccttaa tactgttgac cggaatatac tgcgcggagg cgccgaactt ttgcatgcag
     2881 gccatatggg taaacgtggc cctcggccca aggtaggcaa ccttttgagg cccctcgagg
     2941 gataacgagg ccgacatgat ttcccggtac actgcacgaa tggcctcggt gggaaacggg
     3001 ccggtatttt gcttgctgag ccgatcgaaa atcgccgatt cgcgtgcctg cgtgtgcaaa
     3061 ttcgcgtcgg catctttgag ctttttcagc cggccgatct cgatgaccga tttcgaacgc
     3121 tcattcaaga gacgcaaaat ctgatcgtcg acccggtcga tttcttcgcg atggacttgt
     3181 aagtcatctg acatgacggg gggattccct tctcgcaaca cgcgcctttc acaaagacgg
     3241 gctacgaaac gagtccaggc caaaggggcg ccgttggaca agtgggtatc ctacaggagc
     3301 cactgcgggc attgcaagga taggtctggg gattcaagga gttgcgatcg aatcggtctc
     3361 actggaaaac ggcaacaggt ctttctgttt cttgaaatgt tcgtaggcca acctcgtggc
     3421 ctgtcggccg cgacccgtgc gctccagaaa gcccgcctgg atcaaatagg gttcgtagac
     3481 atcttccagc gtacccttgt cctcttgaac cgccgcagcc agagaatcaa ccccgacggg
     3541 tccaccgtga aacttctcaa tcacggtcaa cagcacgcgg cgatccattt catccagccc
     3601 cgcctcatca accgctaacc ataccagagc atcctgggct actcgctgag tgatgcggcc
     3661 ccccgctttg atctccgcat agtcccggat gcgtttgatc agtcggttga caatgcgtgg
     3721 cgttccacga gcccgcctcg cgatctcagc agcccctgcc tcgtcgatgg gaatattaag
     3781 caagccggct gatcgcgtga cgattgaggt cagctcctgg gacgaataaa attccagccg
     3841 atgcaccaac ccgaaccgat cccgcagagg ggaggttaac gctccagccc tggttgtggc
     3901 tccgaccagg gtaaagtgcg gcaattccag cttgacggtc ctcgtcgagg cgccttgccc
     3961 cacgaccaga tcaagctggt agtcctccat cgccggatag agcgcttcct ccaccgatgc
     4021 cggcaaccgg tgaatttcat cgatgaagag gacatcccgt tcctgcaaat tggtcaaaat
     4081 ggcggcaaga tcacccgcgt gacttaagac cagtccggac gtcgagcgga tcgccgatcc
     4141 catttcccgg gcaataatgt gcgcgatagt cgtcttgccc agtcccggag gaccgtagaa
     4201 aatcgcatgg tccaacgcct cgccgcgacg cttggccgct tcgatgcaaa tctccaagga
     4261 ttccttcatc cgcggttgcc cgacgtactc ccgcaaactc tgcgggcgca gtgccgcctc
     4321 gagtccgcgt tcgtcgtcgg tcagttgatt gcttacggtg cgatcggcca tggcataatc
     4381 tcgaaagaag tggggcgcaa ctatctagtc tcgggtgcgg gccggaattt cggcggcggc
     4441 ggggacgcgc cctgtcccgg agcagccgtg cttccgcaat caggcgggca ccggacgcct
     4501 ccttggctgg gatcgggcat acttgacccc atctgctgcg attgacattg tgacaccagc
     4561 ccgccatcga cggaaccgca acgcgacggc acattcgagc ggccgacctc actatagcct
     4621 tcagggcaag aaccacaaac cgaaagcata ttgctgccta agggcacaca ttgcaccaag
     4681 accggatcgc cgtctttgca gacttccggc gcattcgtcc tcccggtggt ggcgtatcct
     4741 tccgggcacg agccgcaggt tttacggata ctcttgggct cgtccatgcc gtcggcggca
     4801 aagaccccgt ccgtcatgga cgcgcataat aagacggcca ccacgcccaa ggccatcgcg
     4861 ataccgggac gatcctgttt ctttcgtgcg agctccatca ttaccatgtg tcacccctta
     4921 gccaggtctt tgagggcctc ccgaatcacc tgctccagtc cctgagtcag cacacccgat
     4981 tgctccactc gcttcaacgc ctctttcacg tccggctgcc gataaccgag attcaccaac
     5041 gccgataggg catcctcgta gagcggatta tcggatcgac ctgagccagc cacacccagg
     5101 tctccggatg gatgcaactt ggccacctta tccttcagct ccaaggcgat tcttgccgcc
     5161 gactttttgc cgattcccgg tacagtcccc agcttttcaa tatcacctgc ctgaatggct
     5221 gcgtacaggt cacgcacaga gagcgtggat aagacgctaa gccccagctt cggtccgata
     5281 ccggaaatgc cggtcaacaa gagaaaggct tccttctccg aggcagtgaa aaacccgaac
     5341 aactggatgg catcttcccg cacatgggta tgaatgctga gcgtgacagg ctcatgctga
     5401 ttgggcagtg aataataggt actgagggga actaagacct cgtaccccac gccatggaca
     5461 tcgagcgtga cttgcgaggg cgccttgaag gccacaaggc ctgtcagtaa ggcgatcatc
     5521 tgatgagtag gaacgggcgc tgcgaagtga ttaaagaata gactgtgtgt gcgtcgatac
     5581 tcagtgccga aactccggga ttacgcggtg gccgcggcaa ctttctccat gacctcgtcg
     5641 gagatgtcaa agttcgcatg gaccttttgc acatcgtcgt gctcatccag gatctccatg
     5701 agtttcaaca tctgttccgc ggccttctcc tctaatgcaa ttgtattctg gggaatgaag
     5761 tttaattcag caagggtata ctcaattttc gcgtcgctca gcgctttttt gacggcttca
     5821 aaatcatgcg ggctggtcag gacctcgaac gccttgtcgc tgaccttcac atcttcggca
     5881 ccggcctcga gtgcaatggt gagaagcgcg tcctcctcga ccttgccctt ttccacgacc
     5941 agcacacctt tcttatggaa ttgccaggcg acagccccgg cctccgccat gttgccaccg
     6001 ttcttggtta gcaagcttcg gatttcagcc acggtgcggt tccggttgtc cgaggtaatt
     6061 tccatcaaga cggcggtccc tccgggacca tagccctcga gcgtgaactc ttcatatgtc
     6121 acgccgggca attcgcccgt gccgcgctgg atggcctttt tcatggtatc gccgggcatg
     6181 ttggcttcct tggccttggc aatagccaac cgcaggcgtg ggttaccatc agggtccccg
     6241 ccggaccggg ccgcaatcgt caactcacgg atgatgcgcg tgaagacctt gccccgtttg
     6301 gcatcgaccg ccgatttatg ccgtttgatt gttgcccaat gactgtggcc acccatggcg
     6361 actcctcttt gcgctcacag accccgttgc gcatcgggcc tatggacgtg cacgcgaatt
     6421 aaaaatgtac agctaacata gtactgacaa gggtgtcaac gcagcgtcta tccctgcgcg
     6481 gccgcggcga cggtgcggcc tactccgaat aaaacagcag ttggacgccg atgacgagaa
     6541 cgaggatcgc ccagacgagt tcccagtatg atcgctccgt cgcgagctgt ctctggcgcc
     6601 agccggagat cagttttgat gatcccgcaa taatcgccat ggtccccatc atgagatgat
     6661 gtagcgcaat tttgtccgcg gcagggtgat ccccgtggga atgtgagaac aacatgaatc
     6721 ctcccacgac ggcgaagatc ggaagaggcg cggtccacac cgcggtggcg gacctgccca
     6781 gacgccgcag aaactcgatg gtacccactg ctagagccag gaccccgtag gttttatgct
     6841 gcaatacctc cggatccttc ccgaaaaacg tctcggcaaa cgtcatcgac ccgatcggcc
     6901 aggcatcgtg atcgctccaa ataaggagaa acaggccggc cacagccagc gctcccggaa
     6961 gtaaaaagcg cgtccaggtg agcaccggcc atcccagcgc ctggcgtaac tcgctcagcc
     7021 cgatcagcag aagaaagacg ccggccaagt gatgattgaa ttcagaatag gcaattcctt
     7081 cacgcgatcc ttcccattga gaagccgacg gcgaggattc gtggtgatgc ccgtgattct
     7141 cggtggagga gtggccatgg tcgtcagact ctgcaatgga aaaagacccc gtcgaggcga
     7201 gaaccacgaa gcaacacaag gctagcagcg cacaccaaga cctgagaagt ctcagacaat
     7261 aattcggtcg agagagggaa accggcagga atcgaacggc ccatccggag tgccggatgg
     7321 gccgaaaact cgtctcatgc atgcattcgt cgtctacatg aacttcatga acttctcttt
     7381 ggcttcatcc atcacttgcg ccgtgatctc aaccaggccc cgctctttgg caattctctc
     7441 gatttcccgg cgggccatcg ggcgaatgaa gtcaggaatg ttatccatcc gctgttcggc
     7501 atccttggtc caggcgatac cgttaggtga atcgttctta gaatcatcca tgacctgcag
     7561 ggtaatactc ttatacccgt gcttacgcgc ataggcctcg acactgcttt gaaccatggg
     7621 cttcacgaat gacggcaacc gctccaattt ttccttggca tccgccgtcc acgtaaattc
     7681 gcttgtgccg tttccattct gcggcttacc gccggaggtc aatcccatct ccgccaccat
     7741 cgccgagaac ggacaaccgc ccgaggtctt ttctccacca gccgcagggg ccgtggcctt
     7801 cggtgctgcc gtcgccggct ggccaccttg aatcttctca ttcagatagg ctgccatttg
     7861 cccagcacca gcctgtgctt catccttgag ggttccgcga gtcatttcga atggttctgc
     7921 ggtttccgtg cggcctccca atttaactcc aagcgacgcg accatttgtg tttcgccggg
     7981 attggtcacc atcgaaaact tggcttcaca ggatggacag ccgaagaaca caccgagtga
     8041 gccctcaccg ggtttttcga ccttctgaaa cgtcatgtag gtctcgcagt tcaggcaaac
     8101 gaacttcata ggctccccct tccaggccgg tctgcttaca gcttttccgc caggactttt
     8161 ttgtaatcca gcaacgattg aatccgcccg acaatctctt gatatttccg gatcgtcgga
     8221 tagtcgggat caaggagcgg ctgcccctta tcgaacgttt tcgcgagcgt gcgatcaaag
     8281 ggaatacgac ccagcaaggg cagatccaac acctcgcaca tcgcctcggt atttccttca
     8341 aacagctcgt tttcagcgcc gcaggacggg caccgatatt cgctcatatt ctctacgata
     8401 cccaacaccc ggatacccat atccctggcg taggtgactg atttttgcac cacatcggag
     8461 gcaacttctg aaggcgtcgt gaccacgatc gcaccggcca ggtcgggaat aaaccctgcg
     8521 atgaccggtg gcttatccgc agccgctcca ggcggcaagt cagccagaag ataatccagc
     8581 tcaccccaca ccacgtcagc aaggaactcc cgaatcacgt tcatttccat caagcccagc
     8641 cagaccggac tcaagtccat ggggcccttc cagcgaacag gcgaggcgtc acccaggaaa
     8701 aaatccatcg acgcgacctt gatgccgagc ggcccgacag ggggttgggc tccttccgga
     8761 gtcatggtca gcgactggcc atgcagaccc atcatccgcg gaacgcaagg gccgttcaaa
     8821 tcgacatcga gcaatccaac cttcgccccc tggcgcgcaa acgccagggc gagattgacg
     8881 gttgtcatgc ttttcccgac tccgcctttg ccgctcatca ccaccagttt ctgcttgatg
     8941 ccggccatgc gagcctgcac ctgcttcatc tgcgcggtga tctgttgcac gactttggcg
     9001 tcgtcggaat actggagttt tgtcaggatc gacttaagat ccttcccggc agccatggtc
     9061 atgaaaaacc ctcgaaattg ttgatgaagg acgctaccac aggggtttcg gtggagtcaa
     9121 accgccacca ggcgccttcg tcagatcgaa tactgaatgt tcgatttggt cccggacggc
     9181 tggatcagca cgcctcgctt cttcaattct tcaatgattt ggcgtgcggc ggcatcgaaa
     9241 tcctgcggcc cggcaaaatg caagtcggta ttgggcggag gctcttcccc ggctctgctc
     9301 atgtgcacgg caatcaccgg tgccggctga accaaagttc gtatcatctc ggccatgcgt
     9361 tgataattga tgccgaatgt tttgctcgtc gagaccacaa tcagccccgt gtcgatcaac
     9421 aaccgcgcga cttcgccata tcgacgaacc cgctcggacg caaacgacgg atccgcggcc
     9481 gataaatccg catccaaccc ctgcagcaga ttttcacctt ccaataaata ggcatgccga
     9541 ctatccgcga ccaacaatgc ttccacccgc cgcgcgagaa acgtcttgcc ggtctgggcc
     9601 gagccggtaa agagcacaat ggccgcacgg tggccgtact gcagcgcccg gtcttctggc
     9661 ctgacgtcac ccgtgagcca ggcatattcc cgctgacgtg cctcttcacg tagaccttcc
     9721 tgttcgtcgt gcaccaattc ggtgatgatg ccgcctccgg aaatgtcata ttcgtccacc
     9781 agcacgaaac ggcctgtgga ttcgaacgag gacgaaaggt caaaggcgag cggagatttc
     9841 acccgcaggg tcaattcagc cacctgattt ctggccaccg attggctctc ctgcagctgc
     9901 gccaggtcag cagtgtcgat aatgcgatgg atgactgcca cctcgcaggc cacctcccga
     9961 gtggccaaac gcaacacata tttccggccc ttttccagag gccgcctgcc catccagaac
    10021 aaattcacac ggaccgctgt cgaaaccagc ggcaccgaat cccgatgcga cgcgatctct
    10081 ccacgctcca caaagatctg ttcgtcgagt gtaatgccga ccgattggcc ggcctgcgcc
    10141 tcgctcggag gcggatcgac attgaaccct tcgatggatt gcaccaccgc ggttttattg
    10201 gagggagaaa acacgagctg atcgccgacc ttcaaccgac ccgccgtaat gcgtccggcg
    10261 agaattcttc gtgcatcaaa cttgtaaaca tcctggagag gaaagcggag cggttgctct
    10321 gaacgaacct gctctttctt gaagagcgcc agggtctcca agacggtggg gccttgatac
    10381 cagttcatat gggtactgcg cgtcgcaatg ttgtcaccca tcttggcact gaccggaatc
    10441 atttgttgcg gtaccgccct gaactgcccc aggaattccc gatattcttt ttcaataccg
    10501 tcgaacacat cctgtcgata accgaccagg tccatcttat tgacgacgac cgcgaattgg
    10561 gtcacgccca acagcgatag caggtatcca tgcttcttcg attgttcacg cacaccctct
    10621 agggcatcga tcagcaagag ggcggcttcg gcccgggcgg cgcccgagat catattcttt
    10681 aaaaattcct tatgccccgg cgcatcaatg atgatgtatt gccgcccgtt ccagataaag
    10741 aacgtgcgcg ccgtatcgat cgtgatgccc tgttcctgct cttccagaaa cgcatcaaac
    10801 agaaatgcgt actcgaactc cttgccctgt tgccggcaga tcgcctgcac cttttccaac
    10861 ttgccttctg gcaatgaacc ggtgtcggcg tagaggcgcc ctaccagcgt agatttcccg
    10921 tgatcgacgt ggccgacgat gacgatattg aggctttctt gcggtttggt ctggtcgtgc
    10981 tgtgtcatat ggttactcat gcaatggaac tctcattgcc caatttcgtc tgataccggc
    11041 agccggacgg cggaaaccgg acttacatgt agcccttctt acgcagcatc tccatgcctc
    11101 gccccgcatc ctgcgcacgg ccggcccgtt cagccaccgt gctcttgcgc agctctacaa
    11161 tgatctcgtc aaccgtcttc gcggtcgact tgatgggcat ggtgcagggg gcacagccga
    11221 ggctgcgata gcgtgtgcca tcgcccctgt cgagatacag atccatgaag ggaatgttct
    11281 cgtgcttgat atattcccag atattgatct cggtccaatc gagaagggga tgaatccgga
    11341 tatgtgtccc cggagggaac gtggttttga actgatccca caattcaggc ggctgatcgc
    11401 gaaaatccca atcaccgtgt ttgtcacgcg gagaaaagta tcgctctttc gccctggtgc
    11461 tgtcttcgtc tgcacgaaca ccgagaataa tgccagtata gcctttttcc tcaacgagat
    11521 tcttcatggc gtttgtcttc aacgccgtac agcagacatc ccgccccaac gtatgattca
    11581 ttcccgcggc caacgcttcc ttgttctggc ccaccaccag attgagccgc cattcgcgcg
    11641 caatccggtc acggtattcg atcattgccg gaatcttgta actcgtatcc acatggagca
    11701 agggaaaggg cacatgcccg aaaaaggcct tgcgagcgag ccacagcaag acggttgaat
    11761 ccttccccat cgaccagagc atggcgaggt ggttgaagtg cttataggct tcgcgaagaa
    11821 tatagacgct ttggtcttca agttgacgca aatgtttcat gattcacact cgtgtattta
    11881 tgcggacagg ccgaccttcg accccgctgc tgtttcggac cccggccccg cgatcagttc
    11941 tgacagtttg gcttttgctc gaccggactc caacgcattg cgggcggccg ccagattccc
    12001 ggtgatcgac gtcccctttc cagccgcata cagcaacatg gcggcattga gtaggaccca
    12061 gtctcgttgc ccgccctgga tctcgttagc gaccaatcgc ttgatcaggt ccgcttcccg
    12121 ttcgcgctgc tctgccggga aacctgccat ctcgcgaaac gtcgccatgg ccagcccggc
    12181 gtctttaggt tgaaacgtaa agggcgtgat gcgttcgtcc ttgagttcga ggagacgggt
    12241 tgagttaccg atcgaaagtt ccgggtctcc ttcgacgcca cggatcacca gcgcgcgcgg
    12301 acaactcaac atccgcaagg cctcgatagt tttctcgaaa tacggcggat gcgacaagcc
    12361 gatcacctgg gaagcggcac gggccggatt cagcattctc gccaccgggt ggaagaaatt
    12421 gcgcacaccc aattcctgcc gcatttccag aaaccggctc accggcgggt gatacagcgc
    12481 cagatccaga taggcaaacc ccttcttttc caattcaggc ccgacgagct tggccgtctg
    12541 atcagtcgga ataccgagga gctttaagac cgaggacacg ccgcggcgat cagcggggcc
    12601 atccacaccg tgcagcaaca ccacggcgcc ggctgcagcc gcaatgatcg cggcgggcac
    12661 aatggcgtga aacgtttccc tctttcccgc atagacgggc acatccacga cacccagtcc
    12721 ggagcgcacc ggcaccggag gaacatattg tctggcggtg gcggtgaacg cagctaattc
    12781 cgtgaccgac tcggacttga accgcatggc cgtcagaaac gcgccgattt gggcctgcgt
    12841 ggcagttcct tcgatcatca ggcgcatggc ctgcttggct tcttcccagg tgagatcctt
    12901 ggaggtcttt tgacctttgg cgactttcgc gagcagatgt tgcatgtgat ggtattaacc
    12961 ttgtctcgta tcaggatgac gatgatgtta tttatgtaat ccgcattcgg tcttgccgaa
    13021 atttttccac cgaccggaac gcggatcgtc cccgggaagg actggcgcgg tgcagtgcgt
    13081 gcaaccgatg ctgggataat tgcggtcgtg caagatgttg tacggcacct cgtggagctg
    13141 aatatacgtc cacacctgct ccgtactcca ggcggccaac gggttcactt tgacgagctg
    13201 aaatttcttg tcccactcga tcagtccggc gttggcccgg gtcggagcct gatcccgcct
    13261 gattccggtg atccacgcgc tgtactgacc gagaatacgg gtcaatggct cgatttttct
    13321 caactcgcag cattgatcgg gcttgctggc ccataaggcc gctccatgtt gggcagcctg
    13381 ctgctccggc gtcaagagcg atttcatctg aatcacttgc gccggtttca gaccatatcg
    13441 ggccacaatg cggtcgcgca cgtcgaacgt ttccggaaat agaaagtcgg tatcgaggta
    13501 gaacagcggc gcatccggat cgatccgatg caccatatcg accaacgcta catcttccgc
    13561 cccgaagcta caggcgagca cgatcctgcc ctgatacgtc ttcagggcat acgccagcag
    13621 gtcccacggc tgctgagatt caaacgaatc actcagcgcc ttcagctctg cgtcggaagg
    13681 tcgttcagcg gacttctgtg tgtcttgcac tctttctcac ccctcgacct tttccaccaa
    13741 aatcttgaaa tgtttggcct ccggctccaa cgggccttct tcaagaatct tgtgcccatc
    13801 gttccgtaga ctcatcggca cattgcgaat cggctctccg gcatcgagcc agacttcgag
    13861 ctgctcgcca ttgtccatca tttccaattt caatttggtc ttcacataat tcatcgggca
    13921 ggcgacaccg cgcaaatcgt agaccggcgc ggtggcaacg gggctcgcag gctccacttt
    13981 gggagccgga gtcggaacca cctcttcctt cacctgcgcc aacttcaaat ccttgcccat
    14041 ttgttcggtg gccgcccggc agactgagag gaaccgcttg gcaaacgcca tcttgtcatt
    14101 cgccgtttcg gccgtggcat ccttggatcc caaatccccc acctgagcac cgaggttggt
    14161 gtaggaggcg ggtacaatgc ctttgctcgc caagcgcacg tcgaactcct ggaatgtctc
    14221 cgcatcggtc gccggatcga ttccttcggt gaccaacaac cctttggccg ccgccaggac
    14281 cgcgcgatag gacttattca cggacagagc gtattgatgc ttctccacaa gtagtttcgc
    14341 ttgatagagc tcctgatcgg cttccaacat gcggtcgtcg atcatttcca aggctccacc
    14401 tgcgcattcg ccgggcccca gatcctccaa cacaaattcg gcctcacctt cccagtcata
    14461 gtagtaggtg gggtcctggt cgtacgcagg aacaatcgta taggggatga gttcgtcctt
    14521 gaggacgttt tttccgaccc gcccgatgaa ggtttgcaaa ctttcccccg gcttccggtc
    14581 ccggcgatac acatcgacca gatggcggac cgccgccgga acacttttcg ccggcaactt
    14641 caccgcaagc tgcccaattt tcggcgtgcc gtccacgtgc ccgcccaaat gcagttcgta
    14701 atgcggcgcc gtatgctcac cgagccgctt accaactccg tgcaggccga tcgtcgcaat
    14761 atggtgttgt gcgcacgagt tatgacagcc gctgattttg acgctgacgt cgcgcagatc
    14821 ttccggcacc tggccggcag gaaagacctc cgcgagcgct cgggccatcc cctttgacga
    14881 ggtgatcccc aatccgcacg tatccgtacc cgggcaggca atgatgtcct cgacgagctc
    14941 agcgcctgga tcgcccaggc tatgcgcgac gagttcctca tgaaacgcgc tcaaacggtc
    15001 ctcctgaatc catcggatga tcacgttttg attgatggtg gtccggatgt tgccattgga
    15061 atagcgttcg gccaaatcgg caaccaccca catctgttcg cccgtcaaat cgcccatcgg
    15121 taacttgatg gcagccgcag caaatcccgc ctgccgttga ggcaccacat tggtccgctt
    15181 ccaggcctca aacgctgatt cggcgccatt ccgcgatgcg gcgccattgc cgtttccatt
    15241 cccatttccg ttggtgctgt tcggtgcttt cgtcggcatc aacaacggcg gcgtatcggc
    15301 atactcgagc agtttgatcg gttcatgcgt cggcaccgca tatcccatgg ccgcataggc
    15361 cgcctcccag cgacgtttga attcgtcgaa tccgagtttc tcgatgacga acttcatgcg
    15421 agccttgttc cgattcttgc ggtttcctaa ggtatcgaac actttgatca ccgcttcgat
    15481 ggtcggcagc aattcgtcca tcggcgtaaa ttctcgcagc acttgcgcca tgcgcggtgt
    15541 cgatcccagg ccaccaccgg ccaccatccg gaagccaatg gttccatccg cccgtttcgc
    15601 cgcgagcagg ccgatgtcgt gaatgggtgt gagggcgcaa tcctgccggc agcccgacag
    15661 cgcgatcttg aatttccgcg ggagactctg gttcagcgga ttacgcagca gatggtaggc
    15721 aactgttttc gcgtagggcg tcacatcgaa cacttcgccc tggcacactc cggccagatg
    15781 gcacgccgtc acattacgca ccgtgttggc gcaggcttca cgtgtggtca atcccactgc
    15841 cgccaactgg cgcatcatct caggcacgtg cttaagctcc acgaaatgca gctgaatgtc
    15901 ctgacgcgtc gtgacatggc ccacgccggt ggcaaactgg tcggccaatt cagccacgcg
    15961 tcgcaattga ttggccgtca aaccgccgaa tggaattttg atccggaaca tctgcacgcc
    16021 gggctgccgc tgaccataga tgccgtactg caagcggaag ggcttgaaga tgtcggtcga
    16081 gagatcgccg gccagcacac gttgagcttc ggcctcgaat gtctcgattt cttcgacaat
    16141 atggggagga atgggctcag tcttcacagc ggggcgaaga gcctctgtat gactacttat
    16201 cataacgacc tcgtcggttc ggaagtaatg tgcagggcat catgcgggag ttcaaatgtg
    16261 atacatcaat gtatgttgct cgtcgagggc ccgttggcgc tttgccaact cctcgaccgt
    16321 cacttcggat aacacgctga gttccgcccg tttcacacga tcccaaatat gcgcaaggag
    16381 cgcctcttgc ttggaagctc gtgacgaggt ctgtttcgga gcggcgtctc cgttcgtcga
    16441 cagaagcggg ccttctaagg catcgagaat gtccgccaca gagagctccg agggttttcg
    16501 actcaacaca tacccgcctt gcgctccgcg ctgactcgtc accactcccg ccttcttcat
    16561 cgcatgcagc acttgctcga ggaaccgggc cggaatcgcc tgccgcttgg cgatcgactt
    16621 tgcgcacacc ggatgctcgg catggtgaag cgcaagatct acggcagcga tgatcccata
    16681 ggtggctcta aggctaacct tcatttgcga ctattccgat ggggattcat gaatgtctat
    16741 acattgagcc ccgctttcct gtcaagcccg cgggcgcagg cctggttgcg gatatcgcgg
    16801 atgcgctggc ggcgatcacg ttggccgaca attgctcgcc atctctcgga agagatgaat
    16861 ttgctgcgtc gaaagtttct aatttgcatt gcgaattgat gccaccaaca atctcttcta
    16921 ccagtgctca ctttctccac tttgatcgat caggctgcat caataccggt gcagatttcc
    16981 tcattgacat catctggggc ctgagcaata atcccgccct cttcttcctc ggtgcctctc
    17041 atgacgctgc gttcatcaac atttaatatt ctattgctca gcacagacag cgagatccag
    17101 tcacactaca aggacctttt cggtgagcag gcgattaccg ttggccgtga aggcccatca
    17161 ctgcagaagg acctggcaaa gcgcgactac gatgcggtca tcatcgaatc gaagttggct
    17221 gccgcggcgg acttgagcaa attgctgacc ggaatcgatc cttcacgaac cctgctcctc
    17281 gtgggatcgc gtaccgtgct gaaacgcacc gccgccgtgc ttcaggcgtc caaggcctcg
    17341 aaggccgaag cgcctccgtc gaatggcaaa ggacaagctt tgtgtttgga ttcttatctc
    17401 gaacacaagg tcggggattt cgtcaaaggc atgcggaatg gctcagggaa aaatctccac
    17461 ccgatgctga tcgccgcggt cgaacgcccg ttgattcttc tgaccttgcg agagaccaag
    17521 ggcaaccaga tccaagccgc ggagctcctt gggctgaatc gcaatacgtt gagaaaaaag
    17581 attctcgatc tggatatccc cgtcaaacgc gccagggcca gctagcgtac cgacgactga
    17641 gccgcacctc acaaggcgtc ataagtacgc ccatgcatca catccacggg tcgccaacca
    17701 ccaacggagg gaagcaatga ccaaggaaga attgattgca caaatggcga acagtgccgg
    17761 tatcaccaag gtcgccgcaa cagtcgcgct cgaagccttc accggcgcag tcaccacgtc
    17821 gctcaagaag ggaaagcggg tgacgttggt caatttcggc acctttacga tttcaaagcg
    17881 caaggccagg atgggacgca atccgcggac cggcgaagcc ttgaaaattc ctgccgcccg
    17941 cattccgaag ttctcggccg gcaaggaact caaggcggcc gtcaagtagg agtcggcaga
    18001 ctcctggaca gccccacggg acaagacgcg attgcgtggc tcgggcacag agaaaagcct
    18061 gtcttgccac cgcgtttcct tgacaccttt ggtaagcctg tattagcatc gccgatcgat
    18121 aggcgcgtag ctcaggggga gagcgctacc ttgacacggt agaggtcgac ggttcaagac
    18181 cgtccgcgcc taccattttc gttcgctcat gaagttcgtg atccgattac ccgcaggggg
    18241 tggtcggcgc gacgttgtat ttttttggca ggattgaccg gagtggcctc acagctcatt
    18301 cacatcaccc ttcctgacgg aactcgaaaa caagtaccaa caggatgcac cgtccgagag
    18361 gccttaaccc cgcagggagg ccgtctcgac gggaaaatct tggccgcgaa ggtcaacggc
    18421 gtgccgatgg acttgttcca tgcgttggat caagacgcgt ccgtcgaacc gttgaccttt
    18481 gaatccgcgg aagggcgtga ggtgtaccgc catagcagca cccacattat ggctcaagcg
    18541 gtcaaggaag tgttcccgag tgcgcaactt acgattggtc cggcgctcga cgacgggttc
    18601 tactacgatt ttgcgttcga ccggccgttc accccggaag atctggaaaa gatcgaagcc
    18661 cgagccattg aaatcaccaa gcgtggcctg actgtcagcc gtagtgaact atccaaagaa
    18721 gacgcgatca agttttttca ggatcgcggg gaagcctata aggttgagct aatcaatagc
    18781 tttgacgatg gttcccctat ttccctgtac cgtcagggag aattcgtcga cctttgtcgc
    18841 gggccgcacc tgcccaccac cggctacgtg ggcgccttta agctcctctc gaccggcggc
    18901 gcctactggc gcggggacga acgcaatccc atgctccagc gggtgtacgg cacctcgttt
    18961 cccacgaaaa aggaacttga tgcccatctg gcaaaactcg aagagatcaa gcgtcgcgac
    19021 catcgcaaac tcggcaaaga gctcgacctg atcacgattc aagacgacat cggtcccggc
    19081 ttggtgctct ggcatcccaa aggctccctg atccggctgc tcatcgaaaa tttctggcgg
    19141 gagcaacaca tcaaggacgg ctacgacctg gtgtattcgc cgcatgtcgc gaggctcgac
    19201 ctgtggaaaa cgagcggcca cgtcgactat taccgcgaaa acatgtttgc ctcgatgaaa
    19261 ctggaaggca gcgagtatca gctcaagccg atgaactgcc ccttccatat catgatctac
    19321 aaatcgcact tgcgcagcta tcgcgatttg ccgatccggt acggagagtt gggcaccgtc
    19381 tatcgttacg agcgaaccgg cgtgctgcat gggctgctac gggtccgcgg cttcactcaa
    19441 gacgacgcgc atttgttctg ccgacccgat caaatcgagg ccgaagtcag ccgcgtgctg
    19501 gacttcacct ttttcgtgct tggcaccttc ggattcacgg aatttgaaat ttacctctcg
    19561 accaggcccg agaaatccgt gggatcggat gagaactgga ccatcgccac caacgccttg
    19621 gaagcagcgc tgaagagccg caacgtggcc tatcaggttg atccgggtga aggcgtattc
    19681 tacggcccga aaatcgacat caaaattaaa gatgtcctgg gtcgatcatg gcaatgctcg
    19741 acggttcagg tcgatttcaa caatcctgaa cgcttcaagc tggcctatac cggcgaagac
    19801 ggtaaacacc atcaaccgat catgattcat cgggcgctca tgggatcgat cgagcgcttc
    19861 tttggcattt tgatcgagca ctatgccggc gccttcccga cgtggctggc tccggttcaa
    19921 gccgttgtac tgacaatcac cgaccatcaa caggaattcg cggctaagat cgtctccacc
    19981 ctcaagagcc acggctaccg tgttgaagcg gacctccgca acgagaagat cggtttcaag
    20041 atccgcgagg cggaaaagaa caagattccc tatatgctgg tggtgggcga taaggaagtg
    20101 cagagcggca tggtggcggt tcgcggtcga agcaaagctg atcatgggac catgccgatc
    20161 gaacaattcc tggaactcat ccgcacagac acgaatcaat cattacgcga tacagcaacc
    20221 cactcacaaa cgaggtgacc tatcgtccct aaattacgtg taaaccggga aatcaggatt
    20281 cgggaagttc gtgtcatcgg tcctgacggc gagcaattgg gaatactgcc gaccgtagag
    20341 gcattcaata aggctcagga agggggctac gatctcgtcg aggtggcccc gacctcacag
    20401 cctccggttt gccgtatcat ggactatggg aaatataagt tcgagctcag caagaaagat
    20461 caccagagcc gtcggcacca gaaatccacg caggtcaaag agatcaagct gagaccacgc
    20521 accgacaaac acgatctcga gatcaagatc cgccagatca aagagttttt ggccgatggg
    20581 aataagacca aggtgacgct cacgtatcgt ggtcgtgaga tggccaatca ggaaatgggt
    20641 cgcacgatga tgacgagtgt gatccagcag tgcatggaag cggggaccgt tgaatttgcg
    20701 ccgaggatgg aagggcggag cctgattatg attttggctc ccaaatagtg tgcgcgacgc
    20761 acgcaaggaa ggaatgagag catgaagcag aagatgaaaa cccacagcgg cgcgaagaag
    20821 cggttccgac gaacgggaac gggcaaattg gttcgccgaa aggccggcgg tcggcatttg
    20881 ttgaccggca agccacgcga ccgcaagcgg aacttgaagg gggccacgga agtctcgtcc
    20941 gcctcgacac ccgcgttgaa caagttgctt ccgcagtaac gatgattgtg ccgtgaacag
    21001 gatctgaaag gagtagcgtc ccatgcctcg tacaaaaggt ggtccgaaaa cacgacagcg
    21061 gcgaaagaag cgcctgaaac tggcgaaagg ccagtacggc gccaaaagcc ggctgttccg
    21121 aacagcaacc gaatcagtcg ataaagggca ggcttacgcg tattcagggc gaaagcagcg
    21181 gaagcgtgat ttccgccagc tctggatcgc gcgcatcagc gccgcgaccc gcttgcatgg
    21241 cattgcgtat agccgcttca tgaacgccct gaagaaggcg aatatcttat tggatcggaa
    21301 agtgctgtcc gatatggcga tccgggatat ggcggggttt gagaaactcg tcggcgttgc
    21361 caagcagcag ctcgccaccg cagcgagcta acgggttcgc ctcaatgctc tgtgacggga
    21421 agatcctgat ggaacggatt ttcccgtcac gcttcatcca gtaatcgatc gatttccaac
    21481 tccagcgcga ctgccggcac tccaatctgc cactgctcta acacctcggg atgcaactct
    21541 ccgagcagtc cgatagctcg tccatccagc atgattctgc ctgccctgcc ctcaagaaac
    21601 gacgggtgag ggaccggttc caacctaaaa ggacggtcca agtaatagag cagcaagtcc
    21661 aggcaggagt gaatttcgga aaaatgcgcg ccggcatggg cgatgaccgc ccccaacatc
    21721 gtgatcgtcc gtgaaccgac atcggcgcga gcatcgggga cagccacctc accgacctcg
    21781 aacatccgat gcggataaaa cgcccggctc gaattggtct ccacttgcaa caacgaaggg
    21841 gtgatccact ggcgcaggca cgaatagcta agcgacatca cattatccac ttccacgacg
    21901 ttcgcccact c
//
LOCUS       DAOQPD010000064        21610 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1170_length_21610_cov_21.032985, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000064 DAOQPD010000000
VERSION     DAOQPD010000064.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 21610)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 21610)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21610
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1170_length_21610_cov_21.032985"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..634
                     /locus_tag="PK063_13775"
     CDS             <1..634
                     /locus_tag="PK063_13775"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98166.1"
                     /translation="TGDVQSLDYIVTYLRNGFEQTLKPNTTGFSYDRAALVAQRPRDL
                     QAEQQALAETARLAQEAARKEAQQLQKKVQPGSTLLENLAPFVVSPTAGSHYLGMTTV
                     PIKLAPPPGRVTVTLYTVKIERKNPGGTWALVTALPIGLAQASSPSGYLGWGAGGPDG
                     RSLSLMASPGTYRITAQVSAPQQTGWSQPAEFVVMNTNKAIQRAPKTFGP"
     gene            674..1777
                     /locus_tag="PK063_13780"
     CDS             674..1777
                     /locus_tag="PK063_13780"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98167.1"
                     /translation="MNIWHRHAMTVVAGLVLIVALASMCFGFGFNGVGSAPCSSATQQ
                     MVGSFSSTKAQYVSTGTCTTPGSLGAPRTFPYTVKGAYANNIAEEVIEIAAAPISQPS
                     HPYGTWRTTYSCPSDPWLTMDGPPFGPESLRVKCQIVNRMDNSPSEAYPRKYQDGKPL
                     PTLSDLFNAWRAYKPMSAWVLMPAERTALAAKRDADLKAEAAALAKAQAEKRLRSATQ
                     TLTPYRMSLSPIITAPTAGQRFFNQSPISIKLAPPPPWADTEVRLDGTPVKTAKSVTG
                     YMVRLERKDPNGIWVPHATLPVGAAQAESSTGYTGFGAGAPPAFLSIPGAWRLSAQVT
                     TPQQSGWSDWVEFGVMAPPTNKILQPATKSFAK"
     gene            1818..2996
                     /locus_tag="PK063_13785"
     CDS             1818..2996
                     /locus_tag="PK063_13785"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98168.1"
                     /translation="MTPAPARNMSLTWIVGVLGIVVLHCALAVSTEVAVADEPAVVGQ
                     LSMTCSVNTINGTHKPLSSDYAITGQCLLFETSSRGGTAQVNNVAVHWTVQASHQPNT
                     KATFETMNLALSEFGKTTATGTVSSTMQCGSDPWRIMPNGPCRLVTRKTSPPSFPGYV
                     SMAYQQLLQEAPNLPLSFKLNPAQRAAIDKQYHIAMAAQQTFDPSQTTLSKPQGPGVA
                     PFTPGGPNTSDAILSRQMPRILSPASGATVVVGQLLVKIQPPLIGKEPVAELEFAWLD
                     TPAGQPRFVNTIPAMDTAKLLQGQYIDPKVTRLNYGRWEMRVRMIGQGAVAGPWSAPA
                     SFTLVPNQQNQSIQTPSPASPLLKSPSERFGAGTSVIRPRGLNREKSEPSDSAATPAE
                     "
     gene            3028..3711
                     /locus_tag="PK063_13790"
     CDS             3028..3711
                     /locus_tag="PK063_13790"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98169.1"
                     /translation="MNWSLIAGIGFSLTVLSPLEAHAKGDLVAPNDPTCYGSEPKNAT
                     FVATRYTYIFSGSCNLAQTRLAIRVSVPWTGVGTFDPTTGQAAEDILVPAPKISEPSR
                     PYGRFKTTMHCSSDPWLNPTVQCDQIVPTVDAPLDRTAPNAQGYRPEPLAPNIVDIVR
                     ARRRPFTSFMNQDAVNSLNRRFGAYQAQNKTNQVIRQFKKVPGILGRGIEQGDQPSQE
                     TPGTGPSSK"
     gene            3723..5009
                     /locus_tag="PK063_13795"
     CDS             3723..5009
                     /locus_tag="PK063_13795"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98170.1"
                     /translation="MARCPARSAKRLRPDVNGLGLYVLSGALLVLSLGFFPSLSSATD
                     LELIGGPGGSLFRAECPQGSYLVGLAGRTGEWVDRIAPTCAPWLRGSQAFGLPTVGPS
                     FGASGGGQDRQRTCWGTGNKTLAIQSWYVETVRSPNPPVQYVEIHCASLGPAQSIGLF
                     DFGNPTAASEERVTKGPYPHGCPPGEIASGFRVRAGLFIDSLGLICAPIPARLGAPAG
                     KLATPLVQTPPPSVPFNPQAKKLQVPDDLFVITKPVPGERVTQGQLFIAAIPPAVGVT
                     NVAELELRYLDAPPGQKDSYPFVSIMAVNTTKLTQGYLVAPIVTDAYSGRWQVRARAA
                     MKTPPGPWSSPVPFQLTPGAPNKSLTPALQQTPLSGSSVMQAPPATAGGAASSTRPPT
                     TSSQGGASSLFVRPRGVEGTSKKEGNAPAPQSQREK"
     gene            5312..6052
                     /locus_tag="PK063_13800"
     CDS             5312..6052
                     /locus_tag="PK063_13800"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98171.1"
                     /translation="MHVYLPQGFSATATTTVTCPSDPWLGPAVGAGKVACANGSFNTS
                     GQAQDARARFWLDWLRDGFSGSALPNSTGFSYNRPPLIAQRDAALKTETDAAAALQKH
                     NQQILGAARQGPAVVAPVIVLPAANASFLENTTIPIKLLPPAGMQVTSFMVRLERRDS
                     QGNWAVFNNLPVNLAEATSPTGYTGWGAPGTGRGPAMIAGRGSYRVSAQVLSPKPTRW
                     SVPVEFTVTALNKAIQPGPKAFSPGVVR"
     gene            6112..6570
                     /locus_tag="PK063_13805"
     CDS             6112..6570
                     /locus_tag="PK063_13805"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98172.1"
                     /translation="MRRSRPLLLLYALLCLGSALISTPSLAGPPDPCSLLTPAEVEQV
                     VGKLNGAPTSETLGHGVRCGYNFADEKNEFEIWTSEASWSKALRKDAKQPVMVSGLGD
                     EAFMDRGKVDPEAVDLYIRKGATLVLLMTRNGPRVEEQLKTLGRKAIGRL"
     gene            6614..7081
                     /locus_tag="PK063_13810"
     CDS             6614..7081
                     /locus_tag="PK063_13810"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98173.1"
                     /translation="MTRISRRVLFIYLSLAVLVSATPTSLSAAPPNVDPCTLLTIAEV
                     EQTVGALKGKPTGDKEGDAAWCNYEFANGKDALEVWVFPSGAIGRSRAISKNSVTVKG
                     LGDEAFMDRGMHGLNYVNLYVKKGSTTINLSIQETTGDEEKVKALAQKALRRF"
     gene            7397..8152
                     /locus_tag="PK063_13815"
     CDS             7397..8152
                     /locus_tag="PK063_13815"
                     /inference="COORDINATES: protein motif:HMM:NF024853.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HMZ98174.1"
                     /translation="MNRCHSLIATTALILLFTHATLAGSATSSELDPAARQSMEQVIE
                     EYIRAHPEVIEQSLQALEAKREAEEKAKQKVALAAHQAELLNDPTSPVSGNLSGDITL
                     VEFFDYRCGYCKRAAGAVTQLQQENPRVRVIYKDFPILGESSELAAKAALASKAQGKH
                     QVFHEAMLAFKGDITKESLLSLAGEVGLDTIKLEADMRNPEWQKAIDTNRALARTLGI
                     SGTPGFIVGTELVPGALDLNGLKELIARANHKP"
     gene            8339..9505
                     /locus_tag="PK063_13820"
     CDS             8339..9505
                     /locus_tag="PK063_13820"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98175.1"
                     /translation="MNRYLAIVVTGWLLAGWAGCAADSPSSNSNATTIAHTEEATGQP
                     QADEVQERGVTPKPLRPGLTSPQVFTPIPSAPNTASNPPAFGLLPGDFAIRSYLKNTP
                     LTARDGGHHSIDAVITLDSVIGPNQRFRLATVQPDYTTIQTNGGYFVSAVGGLGGLPN
                     TTQGVQTELQTPQRDIALFRIDGPSPAGTFTIKTYDGHFLTALGGGGKSTDAFHTDAV
                     QANSWEYFYFLKCGDVGSGYQYAIRPTGTGNIPGKGDFVSYLTALNGGGMASQAVTAF
                     SGLQVGSRFRLLRQSDGSYALQTSNGVNYLTAVGGGGIASGDNLHTDARQIQAWEKFK
                     IVEQPNCSYTIQTVSGFYLAVGPGSSSISTRISDPNAAPSIGYNAKFELVMVGL"
     gene            10790..11224
                     /locus_tag="PK063_13825"
     CDS             10790..11224
                     /locus_tag="PK063_13825"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98176.1"
                     /translation="MHRLCSHPSLMAGLVCGVIVAAAPALAVPIKNPDNCKGPVTIGV
                     ATCPDKPGHWVECIPSGDYMCCVQNAQGGKDCEQIEALKGPRGGMTRVPGGMLQNAPV
                     VSPAPINPRVPRTGMNAPIMRRGIEDKPSGDGRPGTDDNENK"
     gene            11280..11741
                     /locus_tag="PK063_13830"
     CDS             11280..11741
                     /locus_tag="PK063_13830"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98177.1"
                     /translation="MTKPYAITTVSLMILTGLLALPAASDAKPRKPLVNGCTVDQIQS
                     NFGNSCVDQMQQDIMGNKPYTHALLCSGGQMLCCTYDNTTNQIQTCRKPAGSAFMPGV
                     QGSVGVLGSAGIQRRGVDANTAAEAEEAPAPEWMTPERMQQLQQDFKTNGQ"
     gene            11828..12895
                     /locus_tag="PK063_13835"
     CDS             11828..12895
                     /locus_tag="PK063_13835"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98178.1"
                     /translation="MTIVRYPCTACLVFVMAWGLSMACQAQDNQDSLPSSAPAQEARP
                     NSTEGTTPDEGIKIQEPDLITDDHHPVTGEIQERGIVDKFQATPGKTFMQAQYQAPTA
                     NLTLVANALRLAYKSVSTLVTIAPNLPVTQPVEISIGYYSAAGNDRITQSYVRASGNR
                     FLYNDKEGDGKPRTMTISISLREPKAGGGFETFAVNWQAPLDPLYDVSIGPFAFDLIS
                     KCDAVGKSEILFTWYAPDQQYHKFRFSTRAGSRTTISPFAWSRQEVSWSHKVSRPTET
                     FYDEDNAATEMLWNCLPAGCGFTVAGGPSAQHLLTGASAMVKGNLKAMNDNCQAYFEY
                     PMTKTLRWYPYLDSPTVRDHR"
     gene            12975..14207
                     /locus_tag="PK063_13840"
     CDS             12975..14207
                     /locus_tag="PK063_13840"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98179.1"
                     /translation="MRHTAVVTFVGTAALCLGLAGCAGTDHSKDQAARDVPAREVPVI
                     PEDAPATQDAIQSAESAEVQERGVSRVLPGGTAGAAVLGTLSTPFTSAYPGEFAFRTQ
                     KGYYLTAVNGGGRTGDPTIITGATSAGAWEKFRIGIATPPSPYDRLLQTATGNYLTAV
                     NGGGMTANVLHTDATQPKEWERFRLVYMGGYPPPYYGIGTSKGNFLTAVGAGGRYQDA
                     IHSDARQVQAWEQFRIVKCGDPGSGYEYGIMAADSELFAASTYQGKTWFGLNGHPSEA
                     EMKLKVIRQGDGTYALQTTSGRYVTALGGGGQVEKYDRKYWTPDCGGLFGGPCVGGAS
                     PIFHIDATQVQAWEKFRLVDQGNCTYTIQTTSGFFAGIFKDGSGVTLLTTRRDGAPTA
                     NEKFQLVVFGLASPPIIQ"
     gene            14293..14748
                     /locus_tag="PK063_13845"
     CDS             14293..14748
                     /locus_tag="PK063_13845"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98180.1"
                     /translation="MRSDRVVFIGAISLLTFAVILPAPASARPKGTWQSCNTKDLNTN
                     FGASCNDQMQQDIMGNKPYTHVLFCGGETMLCCTVDNNTNQVINCRKPAGSRVMPGLQ
                     GNTLGASGMAGVQRRGVESKAQDSDEDAPVPSTLTSDVVKELRPKAAAK"
     gene            complement(14882..15841)
                     /locus_tag="PK063_13850"
     CDS             complement(14882..15841)
                     /locus_tag="PK063_13850"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98181.1"
                     /translation="MITFLPFRCQTWLWLLALLMTLHGVVPQAEAQVFPPRSHTQSVP
                     AQPAPPAMGQPMPGPRQQQPVMPGPGLQPMMQPPQVTSPLVKTIPLALLLGGDLSKSF
                     VQLTNLRGQVDSNFTIGRSLAGRFTVPPYVHEASNGSRVFVHANGLSNPPVVKSEGNE
                     LHLEFHLPALQFKTYYRDYSPEGDQAVGDTVGENAIIDIFILPTTNQQGFPTYQAVRA
                     GFRGTLKPQDKCTYWFDVIFPINICEVSKKYLDTLSNAIETGVREALSHPQTRTQFDQ
                     IVWQSLRSDLLIQAGINPMSPAQIRVIEASFHGTDYVVKYLPR"
     gene            complement(16063..17664)
                     /locus_tag="PK063_13855"
     CDS             complement(16063..17664)
                     /locus_tag="PK063_13855"
                     /inference="COORDINATES: protein motif:HMM:NF025684.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4384 domain-containing protein"
                     /protein_id="HMZ98182.1"
                     /translation="MHTRLQPLRTASGTRTSLLIFLPFLLLASCAAAPFLIPAGIEFA
                     RNLLVTSNKNYGGKYSEDMNRLMVRLSTPYVAMGLPMGTSPAALVPPTMLMQQQQAMM
                     NAQASGQAGMGMGMGYPDPYNPAGAMMGGYGAQGYGGMGGYGGMSGYGGMGGYGTSQY
                     GMSQYGYQGQAGGYYDPNNPYASVPGMNVQAPAYGMPQPYGGQYGAQSYGGQMGGYPP
                     QPGYPAQQGLPPQPGYPSAAPGMAAQAPAPGYPPQGMQGYGQQPMQPGMYQQPMDLYQ
                     QQAMQGYQQQPMQQAAMGGYQQPAVQGYQQPVQGYAQPGMAQPYGQPPNVGVSYPAGV
                     YPRGIPGPAEPVALDVALIRQVNGSNGKQVALMQDGETLKGGQDGDRFKLVVRTNCEC
                     FVYVISIDGSGWAQSVFPVANGPVNNPLKPEVEQAFPDGPYWFTLDQFKGVETFFLVA
                     SPARRTDLEESLGQLAGQQRPAGQVAAQVEEPAVIPNGFGKTQSGQAAQVLDDGQQAM
                     QVTPLSYVAAKVGDDVRVTRWFRHQ"
     gene            17834..18418
                     /locus_tag="PK063_13860"
     CDS             17834..18418
                     /locus_tag="PK063_13860"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HMZ98183.1"
                     /translation="MDATHGHNALERTLVARVATGDTQAFEALYRLYDKRVYHYIQTF
                     IRDAALAEEIVGEVMFALWRGACTFTHQSRVSTWIFGIARHKALDAVRRHGRIDHSTA
                     PLDDVPDLPSQQETPIDGIQREQLGIVTRQALSKLSAEHQEILRLVFYEELPYEEIAL
                     LLSIPENTVKTRVFYAKQQLKRHMDRMLSRESVV"
     gene            18415..19092
                     /locus_tag="PK063_13865"
     CDS             18415..19092
                     /locus_tag="PK063_13865"
                     /inference="COORDINATES: protein motif:HMM:NF024881.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="HMZ98184.1"
                     /translation="MTTPHNLAPPHPTATLLPWYLTGTLKESERQAVDEHLASCADCR
                     AELAHLTHLRTPVKTAFAEETTPELRVQQQVMIRIQAETLPAHSAGPTTSKEGAAESV
                     EQWFRRLFAPRWIPALAAILLIGQLTLLLWTAGEQTALPPSHIASRGIQPVSSKIVLV
                     FQDSIPEARIRATILALKGRLVDGPTVDGRYTIEIPSTETAALDQQLHTLQQQSAVIR
                     RAERLAP"
     gene            19142..21373
                     /locus_tag="PK063_13870"
     CDS             19142..21373
                     /locus_tag="PK063_13870"
                     /inference="COORDINATES: protein motif:HMM:NF012862.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="caspase family protein"
                     /protein_id="HMZ98185.1"
                     /translation="MTHRFSTRTILSLAVITLLVVQPVPSFTTEPPSSGTKRALLIGI
                     NRYQVLPTLNGSLNDIDTMRQVLTTRWGFQSQHITMLTDQAATRSGILAALERLVQDT
                     GPSDVVYVHYSGHGSQVEDLNGDETEDHLDETLVPHDGRTPSVPDITDDELEAIVSKL
                     KARSILIVLDSCHSGTATRSLDIRTRSVPQDTRIELYRPSGVHTRQVVPVTAARYVLM
                     TGAAANQEALDGPVGGRYHGFFSYSLSRSLGSAGLSASPREIFFGVEREMKRIQTHFG
                     RISMPEPQLEAPPALMDAPLLPMPSETGNETGTNGTARLPWVEVKAHKGGETLLLNGL
                     QLGAAPGSTWAVYPPNETNFAPGKSLGLLTVTQSRGKDAVTAPHATAFTIPTGSRAIE
                     FLPPASVEGVPVRLLEIPNDRREKIEQVLREQGREVQIVGPGQPAQFLVEVKGNRLQL
                     YSADGLQLVSSFSLDNAQWGAGLARVLSRSANASELLTLDNPSAQIKLDVRIAGAARR
                     QARGIAVVADTQPAQYRIRHEGEPRTPGNSLQLEIQATADSYLTIVDVDSEGHLNLLF
                     PTVHQQPSFYPEGRVRAGDVVTIPDSLQSGNHAGFHWDYAPPAGTDTVRVFASTDLET
                     AQAIRQRVIATTPPGPLATTMVTTRSILSSSMTHLRQDLSRIATRGLSSVYDPTPAAL
                     TNQPSTPPTQTPTAPTAGPSSPQPPVSQNLSPPIAPSTAQTSALTPAADWAATSLTIE
                     VAP"
BASE COUNT         4703 a         6691 c         6152 g         4064 t
ORIGIN      
        1 caccggagat gtgcaaagtc tcgattacat cgtcacctac ctgcggaacg gcttcgaaca
       61 gacgttgaaa cctaatacca ccgggttctc ttacgatcgg gcggctctgg tggcccaacg
      121 accaagagat ctacaggcgg aacaacaggc ccttgccgaa acggcgcgtc tcgcacaaga
      181 agcggctcga aaagaggctc agcagcttca gaaaaaggtg cagccggggt cgaccctgct
      241 cgagaacctt gccccttttg tggtctcccc gacggccgga tcgcactacc tcggcatgac
      301 aaccgtgcca atcaaacttg cgccgcctcc gggacgggtg acggtcactc tctacacagt
      361 aaaaatcgaa cggaagaacc caggcgggac ttgggctctt gtcaccgccc tcccgatcgg
      421 cctcgcccag gcatcgtctc cttccgggta ccttggatgg ggcgccggcg ggccggatgg
      481 acgaagcctt tctttgatgg cctctcccgg aacgtatcgg attaccgctc aggtctccgc
      541 cccgcaacaa accggctgga gccagcctgc ggaatttgtc gtgatgaaca cgaacaaggc
      601 gattcaacgg gcgccgaaga cgttcgggcc ataggaagca ctaggaagat acctttcatc
      661 aatgaggctc cacatgaata tttggcatcg gcacgccatg actgtcgtag ccgggctcgt
      721 cctgatcgtg gccctcgcgt ccatgtgttt cggatttgga ttcaacggcg tcggctcggc
      781 gccctgcagc agcgcgacac aacagatggt cggcagcttc tcttccacca aggcgcaata
      841 cgtctcgacc ggcacttgca ccacacccgg atcactggga gcgccgagga cgtttcccta
      901 cacggtgaag ggtgcctatg ccaataacat cgccgaggag gtgattgaaa tcgcggcggc
      961 tccgatctcg caaccgagtc acccatatgg gacctggcgc acaacctatt catgcccatc
     1021 cgatccctgg ctcacgatgg acgggcctcc gttcggcccg gaaagtcttc gcgtgaagtg
     1081 tcagatcgtg aaccgaatgg acaatagtcc ctccgaggcc tacccccgaa agtaccagga
     1141 tgggaaacct ctcccaactc tcagcgatct gttcaatgca tggagagcct acaagcccat
     1201 gtcggcttgg gtcttgatgc cggcagaacg cacggctttg gcggcgaaac gggacgcgga
     1261 tttgaaggcc gaggcggcgg cattggccaa ggcgcaggcc gagaaacggc tgcgttcggc
     1321 aactcagacc ctgacgcctt accggatgag tctctctccg atcatcactg cgcccaccgc
     1381 gggacagcgg ttctttaacc aatctcccat ctcgatcaag ttagcgcccc ctccaccatg
     1441 ggccgatacg gaagtccgtc tcgacggaac ccccgtcaag accgcgaaga gcgtgaccgg
     1501 atacatggtg cggctcgagc gaaaagaccc caacggaatt tgggttcccc atgccacact
     1561 tcccgtgggg gccgctcaag cggagtcgtc gacagggtat accggcttcg gcgcgggggc
     1621 cccgccggcc ttcttgtcga tccccggcgc atggcggtta agcgcccaag tgaccactcc
     1681 tcaacaatcc ggatggagcg actgggtgga gttcggcgtc atggctccgc cgacgaacaa
     1741 gattctccaa ccggccacca aatcgttcgc aaaataatag tggcagcggt ccggcgcatg
     1801 ataccaggaa ggattcgatg acacctgcac cagctagaaa catgagcctg acctggatcg
     1861 tcggagtgct cgggatcgtt gtgttgcatt gcgccttagc ggtttccacc gaagtcgccg
     1921 tggccgatga accagctgtt gtgggccaac tctccatgac ctgctccgtg aacacaatca
     1981 acggaacgca caagccactg agttccgatt atgcgatcac aggtcaatgc ctcctctttg
     2041 aaacgtcatc gagaggtggc accgcacagg tgaacaatgt cgccgtgcac tggaccgtgc
     2101 aggcaagcca tcagcccaat acgaaggcga cctttgaaac gatgaacctg gcgttgagcg
     2161 agttcggaaa aactacggcc acaggaaccg tgagctccac catgcaatgc ggctcagacc
     2221 cctggcgcat catgcccaac ggcccttgcc gcctggtaac gagaaagacc tcgccacctt
     2281 catttccggg atatgtgtcg atggcctatc agcagttgct gcaggaggct ccaaacctgc
     2341 ccttatcatt caaactcaat cccgcacagc gcgcagcgat cgacaagcaa tatcacatcg
     2401 ccatggccgc gcaacaaacc ttcgatccgt cgcagactac cctgtcaaaa cctcaaggac
     2461 ccggggttgc tcctttcact ccaggcgggc cgaacacctc tgatgccatt ctctcgcgac
     2521 agatgccccg catcctcagt ccggcgtcgg gcgcgacggt ggtcgtcggt cagttgctcg
     2581 tcaaaattca gccgccgctc attgggaagg agcccgtggc ggagttggaa ttcgcgtggc
     2641 tcgatacgcc cgcaggacag ccgcgtttcg tcaatacgat tcccgccatg gacacggcaa
     2701 aactgctgca aggccaatac atcgacccga aagtcacgcg gctcaactat ggccgctggg
     2761 aaatgcgtgt gcggatgatc ggccaagggg cagtggcagg accatggagc gctccagcgt
     2821 cgttcacgct cgtgccgaac caacagaacc aatcgattca gaccccatcg ccggcctcgc
     2881 cgttactcaa aagtccatcg gagcgattcg gagccgggac gtcagtcatc cggcctcgcg
     2941 gcctcaatcg agagaagagc gagcccagtg attcggcagc tacgccggca gaataagtgt
     3001 gtacctttag ccacgcaggg agacattatg aactggtcat tgattgccgg catcgggttt
     3061 tcgctcacgg tattgtcacc gttggaagcg catgcgaaag gcgacctggt cgcccccaac
     3121 gatcctacct gttacggcag cgaacccaag aacgccacct ttgtcgcgac acgttacacg
     3181 tatatcttct caggttcttg caacctggcc caaaccagac tagcgatcag ggtgtcggtt
     3241 ccgtggacag gagtcgggac attcgatccc acgaccggcc aggcggcgga ggacattctc
     3301 gtgccggccc cgaagatcag cgaaccctca cgcccctacg gccgcttcaa aacgacgatg
     3361 cactgcagct ccgacccctg gctgaatcca actgtgcagt gcgaccagat cgtacctaca
     3421 gttgatgcac cattggatcg tacggcaccc aatgcgcaag gctacaggcc cgaaccgttg
     3481 gctcccaata ttgtcgatat cgttcgagcc aggcggcgtc cattcacgtc gttcatgaat
     3541 caagacgcgg tgaatagcct caaccgacgg ttcggcgcct accaggcaca gaacaaaacc
     3601 aatcaagtca tccgccaatt caagaaagtc cccggcattc tgggacgagg catcgagcaa
     3661 ggcgaccagc cttcgcaaga aacgccgggc acgggtcctt cgtccaaata ggaaactgat
     3721 ccatggctcg atgtcctgct cgctcagcta agcggttgcg gccagacgtg aacggccttg
     3781 gcttgtacgt attgtctggt gcactgctcg tcctgagcct gggcttcttc ccctcgctct
     3841 cctcggcgac cgatctggag ttaatcggtg gccccggcgg ctctctcttc cgggccgaat
     3901 gcccgcaagg ctcctatctt gtgggcctgg ccggccggac gggcgaatgg gtcgatcgca
     3961 tcgcgccgac ctgcgcgcct tggctgaggg gatcacaggc gttcggatta ccgacggtcg
     4021 ggccgtcgtt cggcgcgagc ggaggcggcc aagaccgtca gcgaacctgt tggggcaccg
     4081 gcaacaagac cctcgctatc caatcgtggt atgtcgaaac ggtcagatca cccaatccgc
     4141 ccgtacagta tgttgaaatc cactgtgctt cactcggccc tgctcagtcg atcggcctct
     4201 tcgattttgg caatcccact gcggcttctg aagaacgagt gacgaaagga ccgtatccgc
     4261 atggatgccc gcctggcgag atcgcctcag gctttcgcgt ccgtgccggg ctgttcatcg
     4321 attctctcgg actgatctgc gccccgatcc ctgcgcggct cggtgcaccg gcgggaaagc
     4381 tcgccactcc actcgtacaa actccgcccc catctgtgcc attcaatccg caggccaaga
     4441 agctgcaagt gcctgatgat ttgttcgtga tcaccaagcc ggtgcccggt gaacgggtca
     4501 cgcagggaca gcttttcatt gccgccattc ctcctgcggt cggcgtgacc aatgtggcgg
     4561 agttggaact gcgctacctc gatgcaccgc cgggacagaa agattcctat cctttcgtca
     4621 gcatcatggc tgtaaacacc acgaaactca cccagggata cctcgtggct ccgatcgtca
     4681 cagatgccta ctccggacgc tggcaagtgc gagccagagc ggccatgaaa actcctcccg
     4741 gcccctggag cagtcccgtg ccgtttcagc tgacgccagg cgctccgaac aaatctctca
     4801 cgcctgcatt gcagcagaca cccctatccg gttcatcggt gatgcaggcg ccgccggcaa
     4861 ccgcgggcgg tgctgcgtcg tccacccgac ccccgacgac ttcctcccag ggcggcgcaa
     4921 gcagcctctt cgtccggcca cgtggagtcg agggcacaag caagaaggaa ggcaatgcgc
     4981 ccgctcctca gtcccagcgg gagaagtagt cgtgaacgcc gcaatccatc gggcgaatga
     5041 acaccattcg gtcatacagg gaggatctat gcgccctcat tggcgactcg gaatatggtt
     5101 gattacagcg cccctcacag tagcgggtgt cggtgtcctg catgcggagc agccggcgat
     5161 acaatgtggc cctcctcgta tcgaggcaag cttcacggcg gccctctcaa gctatcatgt
     5221 caccacctcg tgtagcgcgg tgccagccgg atttgtgaat tgggactctc gcggttccta
     5281 cgactcacac acgggactgg cgagagagga ggtgcatgtc tacctgcctc aaggattctc
     5341 cgcaacggct accaccaccg tgacctgccc gagcgatccc tggctggggc ctgctgtcgg
     5401 ggccggaaaa gtggcctgcg cgaatgggtc gttcaacacg agcggtcaag cacaagatgc
     5461 tcgagcccgc ttctggctgg actggctgag ggacggattc tccggctccg ccctgcctaa
     5521 ttccaccggc ttcagttaca accgaccacc gctgatcgct cagcgcgatg ccgcgctcaa
     5581 aacagaaacg gacgcggccg ccgcgttgca aaaacacaat caacagatcc tgggcgctgc
     5641 ccggcaaggg cctgcggtcg tcgcaccggt gattgtcctc cccgccgcca acgcgtcatt
     5701 tctggagaat acgaccattc ccattaaact gcttcctcca gcagggatgc aggtgacgag
     5761 ctttatggtg cggctcgaac gccgggatag tcagggcaac tgggcggtct tcaacaacct
     5821 accggtcaac ctggccgaag cgacatcacc aaccggatat acaggatggg gtgctcctgg
     5881 aactggcaga ggtccggcaa tgattgccgg ccggggcagt tatcgtgtca gcgcacaggt
     5941 gctgtctccg aagcccacgc gctggtctgt tccggtggaa ttcaccgtga cggccctgaa
     6001 caaggccatc cagccaggac cgaaggcgtt cagtccggga gtcgttcgat gatcgtggac
     6061 cgactccatt tggcctggac acaccacgtt ttcatcgtga agggaggcac catgcggcgc
     6121 tcacgtcctc tcctgttgtt gtacgcatta ctctgcctcg gcagcgcgct catttctacg
     6181 ccaagcctgg ccggccctcc ggatccctgc tcgctcctga cgccagcaga agtcgaacag
     6241 gtggtcggca agctcaacgg cgccccgacc agcgaaacac tgggccatgg ggtgagatgc
     6301 ggctacaact ttgccgacga gaaaaatgag ttcgaaatct ggacgtctga agcctcctgg
     6361 tcgaaggcgt tgcgcaagga tgcgaaacag ccggtcatgg tcagcggact gggcgacgaa
     6421 gccttcatgg atcggggcaa ggtcgatccg gaagccgtgg atctgtacat caggaaaggc
     6481 gcgaccttgg ttctactgat gacgagaaat ggtcctcgcg tcgaagaaca actaaagacc
     6541 cttggcagga aagcgatagg ccggttgtaa ttccccgaat tggatttcca agttgccacg
     6601 tgaaggagtc ggcatgacac gaatttctag gcgcgtctta ttcatatacc tgtccttagc
     6661 cgttcttgtt tcggccacac caacatcact atcggcggcg cctcccaatg tcgatccttg
     6721 caccctcctg acgatcgccg aagtggaaca gaccgtcggt gcgttgaagg gcaagccaac
     6781 gggcgacaaa gagggcgatg ccgcctggtg caactacgag tttgccaatg gcaaggatgc
     6841 attggaggtg tgggtgtttc catccggggc catcgggcgg agcagggcca tctctaagaa
     6901 ttccgtcacg gtaaagggtc tgggcgacga ggcattcatg gaccgtggta tgcacggact
     6961 gaattacgtg aatctgtacg tgaagaaggg cagcacgacc atcaatctgt cgattcagga
     7021 aaccacgggc gatgaagaaa aggtcaaggc gttggctcag aaagcgttac gccggttctg
     7081 aaggaaatac ctgcattatt ccatcacgca gttgacccag aactgcggtg ctgcgtatgc
     7141 tccagcttcc cgaagtccgg tcgcaaaggc ttaccgggcg tggcttcgcg aggatcagca
     7201 tgattccacc atctgccgat tatccagctg caccgccctc tccagccact cttatatctc
     7261 cgttgaacct ttcaccttgc gcgtccgaca tacggcgcat gaacgaaatc acaaggatgg
     7321 atcgccgagt gctccgaccg tccgcgctgc gccacacaac cagacaccgc accatgacga
     7381 gactgaagga gggccgatga atcgctgcca ttctctcatt gccaccaccg cactcatctt
     7441 gctgttcact cacgccactc tggccggatc cgccacctca tcagagctgg atccggccgc
     7501 acgccaatcc atggagcagg tgatcgaaga atacattcgc gcccatccgg aagtgatcga
     7561 acaatcgctc caggcattgg aagcgaaacg cgaggcggag gagaaggcga agcagaaggt
     7621 ggcgctggca gcccaccagg ccgaattgct caatgatccc acgtcacccg tgagcggcaa
     7681 cctctccgga gacatcacgc tcgtggagtt tttcgattat cgctgcggct actgtaaacg
     7741 cgcggccggc gccgtgacgc aattgcaaca ggaaaacccg cgtgtgcggg tcatctacaa
     7801 agactttccc attctcggcg aatcgtctga actcgcggcg aaagccgcgc tggcctcgaa
     7861 ggcgcaaggc aagcaccaag tattccacga agcgatgctg gccttcaaag gcgatatcac
     7921 caaagagtcg ctgttgagcc tggccggcga agtcgggctc gacaccatca agctggaagc
     7981 cgacatgcgc aatcccgaat ggcaaaaggc gatcgacacc aatcgcgccc tggcacgcac
     8041 tctcggcatc agcggcacgc ccggattcat cgtgggcacg gaattggtcc caggcgcatt
     8101 ggacttgaac gggctgaagg aactgatcgc acgggcaaac cacaagcctt agccgtgtct
     8161 tgaggagtga tcggggatca atgttcactg gcgtctcgcg cggctcgata cgcaccgtgc
     8221 cggaccgggg ctcagggcat tgctgtcgat ggatgtggtg agaacgacga gcggagatga
     8281 tcccgtcgcg ggagtggaag agttcagagt gcctcacgaa caaaattgga ggtgccgcat
     8341 gaaccggtat ctagccattg ttgtcaccgg ctggttgctc gcgggatggg ccggttgtgc
     8401 tgcggattcg ccgtcatcga attccaacgc taccactatc gcccacacgg aggaagccac
     8461 aggtcaacca caagccgacg aggtgcaaga gcggggcgtc accccgaaac ccctccgacc
     8521 cggcctcacc tccccgcaag tgttcacccc gattccgtca gcaccgaaca cggcatcgaa
     8581 cccgccggcg ttcggcctgt taccgggcga ttttgcgata cggtcgtacc tgaagaacac
     8641 tcctctgacc gcccgagatg gagggcacca cagcatcgac gccgtcatca cactggatag
     8701 cgtgatcgga cccaaccagc gatttcgcct cgcgaccgtc caaccggatt acaccaccat
     8761 ccaaaccaac ggcggatact tcgtgagtgc cgtcggtgga ctgggcggcc tgcccaatac
     8821 gacacagggg gtacaaaccg aactccagac tccgcaacgg gatatcgcgc tgttcagaat
     8881 cgacgggccc agccctgccg ggaccttcac gatcaagacc tacgatgggc attttttgac
     8941 cgcactcggt ggaggcggca aatcgactga tgcgttccat accgatgcgg ttcaggccaa
     9001 ctcttgggag tatttctatt tcttgaaatg cggcgatgtg gggtccggct accaatatgc
     9061 cattcgcccc accggcacag gaaatattcc ggggaaaggc gattttgtga gctacctcac
     9121 cgcgctcaac ggaggaggga tggccagtca ggccgtgacc gccttcagcg gcttacaagt
     9181 cggatccaga ttcaggctcc tcaggcaaag cgatggatcc tatgcgctgc aaacctccaa
     9241 cggagtgaac tatctcaccg cagtaggcgg aggcgggatc gccagcggcg acaacctgca
     9301 tacagatgca cgacagattc aggcctggga aaagttcaag atcgtggagc agccaaattg
     9361 ctcctacacc atccagaccg tcagcggttt ttatctggct gttggaccgg ggtcctcctc
     9421 gatctcgacc aggatcagcg atccgaatgc cgcgccatcg attggctata acgccaagtt
     9481 cgaattggtc atggtgggac tgtaagtacg gacgcacgaa gtgtcctgac gcagaaacat
     9541 atcaccggat tatttgatcg cgcggagcac cagggctgat gaggcctagc atctgaagtg
     9601 agcatccgta tggagaacag gaggctggaa tgaacactcc cactacatgc accgagagcc
     9661 gaggtacgat acgtgcgcgg agtcgcgggc gctggtttgt cctaactggt gcaggcgtat
     9721 gcacgatact cagtctcttc ctgcagtcag atatcagttg ggccaaaccc aaaaagaaca
     9781 cttactggtc gtgtaaatgc agctgccgct gggtagacga actcgggaaa gagcatttcg
     9841 ggccatcggg ggccgtgcag tttactgaat caagcttgga agcctgcctt ggccattcct
     9901 gcacaactac cacaccgacc ggcacacacc agggcacgac cagagattgc atgggcaccg
     9961 agcagcaaag tcagatgcga ctccccccag gtggggtgca aggacaactt caaccagccc
    10021 aaccggggct aggaagagtc cctgcccctg ttgtccccgg aaccatcatg cggcgcggag
    10081 tggacggcga ccaaccgact tcctcggaaa aagaaggaaa ataaaggtga gcgagagaat
    10141 ggaatcatgg acatgaaatc gacacggttc gtcacatggg gctgggtgat gctcatcttc
    10201 gtactcacga ccggctatcc tgtctctgca tccgctgaac cagtggaggc acccgctgtg
    10261 aaccaaccgt ccggtgaaga gatccaggag cgcggcgtgg caccagggct gttgggggaa
    10321 atgaaaaaag accttcaacg aaggcccctt gcccctggtc cggcaggtcc gccgccacaa
    10381 ctctgccata ccgaaacgca catgatgacc cagtgcaagt gtttcaacca ggcggactgc
    10441 caaagcctca ctgtgctctt tcccaattcc tgcccgtctg gaagtactca ctgcgaattc
    10501 atccccatga gccgcggtcc gatgccggcc ctgccgccga atctgtgcag ttaccaggtc
    10561 ccgtttcctg tgacccgatg cgcctgccat acccaggcag aatgccaatt gttgtcgcca
    10621 ttttgtcccg cagcctgtcc ggcaggaagt cagagctgcg aatgcacgcc atttcaacgg
    10681 cggtaaatag agtactgaca ctcggaacca tcgaattgcc gaaagaggac cgacgatcct
    10741 gatgttatcg ctaaacgaat tgaggagtca cagaacgaag gaggccgcca tgcatagact
    10801 atgttctcat ccaagcctca tggcaggact ggtgtgtgga gtcattgtcg ccgccgctcc
    10861 cgcgttggcc gtgccgatca agaatccgga caactgcaag gggcccgtca cgattggagt
    10921 ggccacctgc cccgacaaac ccggccattg ggtcgaatgt attcccagcg gcgattatat
    10981 gtgttgcgta caaaatgcgc agggcggaaa agactgcgaa cagatcgagg ccctcaaagg
    11041 cccaagaggc gggatgacga gagttcccgg cgggatgctg cagaacgcgc ccgtcgtatc
    11101 gcccgcaccg atcaatccac gcgttccgag aaccggcatg aacgcgccca tcatgagacg
    11161 aggtatagag gacaaaccct ccggcgacgg gcggccaggc acggacgata atgagaataa
    11221 gtaaaacaac accgacattc gatcattgac gtgttcagat gatcgagaaa gagtacacca
    11281 tgaccaagcc ttatgcgatc acaaccgttt cgctcatgat cctgacgggg ctcctggcgc
    11341 tccctgcagc gtcagatgcc aaaccgcgaa agcccctggt caacggctgc accgtggatc
    11401 agattcagtc caatttcggc aactcctgtg tcgatcagat gcagcaagac atcatgggaa
    11461 acaagcccta cacccatgcc cttctctgca gcggcggtca aatgttgtgc tgcacctacg
    11521 acaataccac caaccagatc caaacctgcc ggaagccggc aggctcagcg ttcatgccgg
    11581 gagtccaagg aagcgtgggc gtgctcggca gtgccggcat ccagcggcgt ggcgtcgacg
    11641 cgaacaccgc agcggaggca gaagaggctc ccgctccgga atggatgacg ccagagcgta
    11701 tgcaacagct tcaacaggat ttcaaaacca acgggcaatg agcagagctt gttataacga
    11761 cgccgcgtag aggttgcatg cgagacagcg tcgcaggctg caggcacaag gacaaaggag
    11821 tagatgcatg acgatcgttc ggtatccctg tactgcatgc ttggttttcg taatggcttg
    11881 gggcctgtcg atggcctgtc aggcacagga caatcaagac tccttgccct cgtcggcacc
    11941 cgcacaggaa gcgcggccga actcaactga ggggaccact cctgacgagg gcatcaagat
    12001 tcaggaaccg gacttgatca ccgacgatca ccatccagtc actggcgaga tacaagaacg
    12061 gggcatcgtg gacaagttcc aggcaacacc cggaaaaacg tttatgcagg cgcaatacca
    12121 ggctccgacc gccaacctca ccttggtggc caacgccttg cgactcgctt acaagagcgt
    12181 gagcacactg gtcaccatcg cccctaacct ccctgtgaca cagccggtag aaatcagcat
    12241 tggctactat tctgccgccg gcaatgaccg catcacccag tcgtacgtgc gggcctcggg
    12301 caatcggttt ctgtataacg acaaagaggg cgacgggaag ccgcgcacca tgaccatctc
    12361 gatctccctg cgggaaccca aagccggcgg aggcttcgaa acgtttgccg tgaactggca
    12421 ggccccgctc gatccattgt atgacgtcag catcggacca tttgcgttcg acttgatcag
    12481 taaatgcgat gcggtcggca aaagcgagat cctcttcacc tggtacgccc ccgatcagca
    12541 atatcacaag tttcgattca gcacccgcgc cggatcccgc accaccatca gcccgtttgc
    12601 ctggagccgt caggaagtga gctggtcgca caaggtttca cgtccaaccg aaacgtttta
    12661 cgatgaggac aatgccgcga cggaaatgtt gtggaattgt cttccggccg gatgtggatt
    12721 taccgtggcg ggcggtccct ctgcacaaca tctcctcacc ggcgcgtctg cgatggtcaa
    12781 gggcaatttg aaagcgatga acgataattg ccaggcctat tttgaatatc ccatgaccaa
    12841 gacgctccga tggtatccct atctcgatag tcccacggtg cgcgatcatc gataggctgc
    12901 aggaccgcga atgcgaagcc ataccgggaa actctcacag gatgcaccat cattttcgga
    12961 ccaggagggc tgagatgcga catacagcag tcgtcacatt cgtgggcacg gcggccttgt
    13021 gtctgggact ggccggttgt gcggggacag atcatagcaa ggaccaggcg gcacgcgatg
    13081 tgccagcacg cgaagtacct gtgattcccg aagatgcgcc ggctacgcag gacgccattc
    13141 agtctgccga atcggccgag gtccaggagc gtggcgtttc acgcgtcctt ccgggaggca
    13201 ccgcgggtgc ggcggtattg ggcacgctct cgacaccatt caccagcgcc tatcctggag
    13261 aattcgcctt caggacgcaa aaaggttact acctgacggc cgtgaacggc ggaggacgaa
    13321 ccggtgatcc gaccatcatc accggcgcca cgtcggccgg agcctgggaa aagtttagaa
    13381 tcggcatcgc gaccccgcct tctccgtacg acagactcct ccaaaccgcg accggcaact
    13441 atctcaccgc cgtcaacggc ggcggcatga cggccaatgt cctgcacact gatgcgacac
    13501 agcccaaaga gtgggagcga ttccgtctgg tctacatggg cggctacccg cctccctact
    13561 acggcatcgg gacgagcaag ggaaacttcc tcactgccgt aggggccggg gggcgctatc
    13621 aagatgcgat ccacagcgat gccaggcaag tccaagcctg ggaacagttt cgcatcgtga
    13681 agtgcggtga tccgggatcg ggctatgagt acggcatcat ggccgccgac agcgaattgt
    13741 tcgcggcgtc cacctatcaa ggcaagacct ggtttggcct gaatggtcat cccagtgaag
    13801 ccgaaatgaa actgaaggtg atccgtcaag gcgatggtac ctacgcgctt cagacgacga
    13861 gcggacgtta tgtcacggca ctgggcggag gcggacaagt cgaaaagtac gaccggaaat
    13921 actggacccc tgattgcggc ggcctcttcg gcggcccttg tgtcggaggc gcttcgccca
    13981 tttttcacat cgatgcgacc caggtgcagg cctgggaaaa gtttcgcctc gtcgatcagg
    14041 ggaactgcac gtatacgatt caaaccacca gcggtttttt tgccggcatt ttcaaagacg
    14101 gatccggcgt aacgttgctg accacgagac gggacggagc gccgacggcc aatgagaaat
    14161 tccaactcgt cgtcttcggc cttgcgtcac cgcccattat tcaatagcgc acatgcagaa
    14221 cgagacccat tacggagctg acgtagctcc cgtagaatcg cgagcccatc acctatcacc
    14281 aaggaggcct ctatgagatc ggatcgagtg gtattcatcg gcgcaatcag tctactgaca
    14341 ttcgctgtga ttcttcctgc tcccgcatct gcaaggccca aaggcacctg gcagagctgt
    14401 aataccaagg atctcaacac caacttcggc gcctcctgta acgatcagat gcaacaggac
    14461 atcatgggca ataaacccta cacccatgtc ctcttttgcg gtggagagac catgctctgt
    14521 tgcacggtcg acaacaatac caatcaggtg atcaactgcc ggaaaccggc cggcagccgc
    14581 gtgatgccgg ggttgcaggg caataccctc ggcgcatccg gtatggctgg cgtgcagaga
    14641 cgaggggtcg aatcgaaggc acaagattcg gacgaggacg cgccggtgcc ttcaaccctc
    14701 acgtcggatg tcgtgaagga attgcgcccc aaggccgccg caaagtgacc cctcgttgtt
    14761 gagcagccgc tggaatgccg ttgacgggac ggagtgagaa attctcactc cgtcccgcac
    14821 acctttcggg cggtcgcgtc aaaacctgca ggcggccccc ccttctctga tgttgagaca
    14881 attatcgagg caggtacttc actacgtagt cggtgccgtg gaaggaggct tcaatcacac
    14941 ggatctgggc gggactcatc ggattgatac cggcttggat gagaaggtcg ctccggaggg
    15001 attgccagac aatctgatcg aactgcgtac gggtctgcgg atggctcaag gcctcacgca
    15061 cccctgtttc aatcgcattg ctgagcgtat ccaggtattt tttcgacacc tcacagatgt
    15121 tgatggggaa gatcacatcg aaccagtagg tgcacttgtc ctgcggcttg agcgtccccc
    15181 gaaaccccgc ccgtaccgcc tggtaggtcg ggaatccctg ctgattggtc gtgggtaaaa
    15241 tgaagatgtc gataattgca ttctcgccga ccgtatcgcc gaccgcctgg tcgccttccg
    15301 gagaatagtc ccgataatag gttttgaact gcagggctgg aagatgaaac tccagatgca
    15361 attcattgcc ttccgacttc accaccggcg ggttggacag gccgttcgcg tgcacaaaca
    15421 cccgggagcc gtttgaggct tcgtgcacat agggcggaac ggtgaaccga ccagccaggc
    15481 tgcggccgat cgtaaagttc gaatcgacct gcccgcgaag gttggtgagc tgaacaaaag
    15541 atttagacag gtctccgccc agcaggaggg ccaggggaat cgtcttgacc aaaggcgacg
    15601 tcacctgtgg cggctgcatc atcggctgca gaccgggacc gggcatcacc ggttgctgtt
    15661 gccgtggccc cggcatcggc tggcccatcg ctggaggagc tggctgcgcc ggcacagact
    15721 gggtgtgaga gcggggtgga aagacctggg cttctgcctg cgggacgacc ccatgcagcg
    15781 tcatcagcaa agcgagcaac cacaaccagg tctgacacct gaacggcagg aaggtgatca
    15841 ttcgttccga gaagaggttc gcatcctgtg ttgttcaaca atcgtcgtct gttcgctcat
    15901 gaccggcttc caggaactac atcgacatgg ggaattcgca ggatgctcaa cgtggttgtc
    15961 cagcaacgcc gcagggatgg aagcggcgag gcgtacatcg cctggtacgt cgagtcgctg
    16021 acagaaccga ggacccagct ggcggccatg ttcagcatcc tgctactggt ggcggaacca
    16081 gcgtgtcacc cgcacatcat cgccgacctt cgccgcgaca taggacagtg gcgtcacctg
    16141 catagcctgc tgcccgtcgt ccagcacctg agccgcctgt cccgactggg ttttgccgaa
    16201 tccgttcggg atgacggccg gctcctcaac ctgcgcggcg acctgaccgg ccggacgttg
    16261 ttgaccggcc agttgcccta gactctcctc cagatccgtc cgtcgcgcag gagaggcgac
    16321 gaggaagaag gtttcgacgc ccttaaactg atcgagcgtg aaccaatagg gtccgtcggg
    16381 aaaggcctgt tccacttccg gcttgagtgg attattcacc gggccgttgg ccacagggaa
    16441 aactgactgt gcccacccgg acccatcgat agagatgacg tacacgaaac actcgcagtt
    16501 cgtccgcacc accagcttga agcggtcgcc atcctgccca cccttcagcg tctcaccgtc
    16561 ctgcatgagg gcaacctgtt tgccattcga tccattgacc tgacggatca gcgcaacgtc
    16621 caacgccacc ggttcagccg gtcccgggat acctctcgga tacacgccgg ctggatacga
    16681 cacgccgaca ttggggggct gcccataggg ctgcgccatg ccgggctggg catagccttg
    16741 caccggctgc tgataccctt gtaccgccgg ttgctgatag ccgcccatcg ccgcctgctg
    16801 catcggttgc tgctgatacc cttgcatggc ttgttgctga tagagatcca tcggctgttg
    16861 atacatcccc ggctgcatcg gttgctgacc gtacccctgc atgccttgtg gagggtagcc
    16921 gggagccggg gcctgcgcag ccatgccggg cgcggcggaa ggatagccag gttgcggcgg
    16981 caatccctgc tgagccggat agccgggctg aggcgggtat ccgcccatct gcccgccata
    17041 cgactgcgca ccatactggc cgccgtaggg ttggggcatg ccataggccg gggcctgcac
    17101 gttcatcccc ggtacggacg cgtagggatt attggggtca tagtaccccc cggcttgacc
    17161 ttgatagcca tattgcgaca tgccgtactg tgaggtgcca tacccgccca ttccaccata
    17221 cccactcata ccgccgtatc cgcccatccc gccgtaccct tgcgcgccat acccgcccat
    17281 catggcgcca gccggattgt agggatccgg atagcccatt cccatgccca tccctgcctg
    17341 acccgatgcc tgcgcgttca tcatcgcctg ttgctgctgc atcaacatgg tcggcgggac
    17401 taacgccgca ggtgacgttc ccatgggcaa tcccatcgcc acgtagggtg tgctcaggcg
    17461 taccatgagc cggttcatgt cttctgagta tttcccaccg taattcttgt tgctggtgac
    17521 cagcaggttg cgcgcgaatt caatgccggc gggaatcaga aagggtgcgg ccgcgcagga
    17581 agcgagcagg agaaacggga ggaaaatgag caaacttgtg cgggtgcccg acgcggtccg
    17641 gagcggctgt aggcgtgtat gcatgcgatc acctcgtacc cgtctgtcgc gccatctccg
    17701 gaaaggttca cgattgtagt ctctcattta tcgaagggtc aaccggcatt gctattgagg
    17761 ggatccagga ttctgtgcta cagcagaagc gccgatcagg accgctggca catttcttcg
    17821 aacatacagg ctcatggacg cgactcacgg gcataacgca ctggaacgta cgctggtggc
    17881 gcgagtggcg accggagaca cgcaagcgtt cgaggccctg taccggctct acgacaagcg
    17941 cgtctatcac tacatccaga ccttcatcag agatgccgct ctggctgaag agatcgtcgg
    18001 agaagtgatg ttcgcattat ggcgaggcgc ctgcaccttc acgcaccaat cccgggtttc
    18061 gacatggatt ttcggcatcg cccgccataa ggccctcgac gcggtcagac gccacggcag
    18121 gattgatcac tccaccgccc cgctcgacga cgtgccggat cttccgagtc agcaggaaac
    18181 tcctattgac gggatccaac gcgaacaact cggaatcgtg acccgccagg cgctctcaaa
    18241 actgtcagcc gaacatcaag aaattttgcg cctggtcttt tatgaggaac tgccctacga
    18301 agagattgcg ctgctgctca gcatccccga aaatacggtc aagacacggg tgttttacgc
    18361 gaaacaacag ttgaaacggc atatggatcg gatgctctcg agggagtctg tcgtatgacg
    18421 acgcctcaca atctggcccc cccgcacccg acggccacat tgctcccctg gtacctgacg
    18481 gggacattga aagaatccga gcggcaggca gtcgatgaac atctggcgag ctgcgccgac
    18541 tgtcgcgccg aactggccca cctcacacac ctgcgtacac cggtgaaaac cgcctttgcg
    18601 gaagagacga cgccggagct acgcgtgcag caacaggtga tgatccgcat tcaggccgaa
    18661 acactgccag ctcactcagc gggacccacc acgtctaaag aaggtgccgc cgaatcagtg
    18721 gaacagtggt tccgccgcct cttcgccccg cgctggatcc ctgcgctggc ggcgatactc
    18781 ctgattggcc aactgaccct cctgctgtgg accgccggtg aacagaccgc cttgccgcca
    18841 agccacattg cgtctcgcgg aatccagccg gtgtccagca agatcgttct agtctttcag
    18901 gactcgatcc cggaggcccg catccgcgcg accatcctgg cgttgaaagg ccgactcgtc
    18961 gatgggccaa ccgtagacgg acgttacacc atcgagattc cttcgacgga aaccgctgcc
    19021 ctcgaccagc agcttcatac cctgcaacag caatccgctg tgattcgacg tgcggagcgc
    19081 cttgcgccat gaaccttttt aaagggtgcg cgactcaccc attgcagccc gagggccttc
    19141 tatgacgcac cgtttctcca ctcgcaccat tctgagtctc gccgtcatca ccctgctcgt
    19201 cgttcagccg gtgccgagtt ttacgaccga gccgccatcg tcgggaacca agcgagcctt
    19261 gctgatcggc atcaatcggt atcaagtgct accgaccttg aacggctcac tcaacgatat
    19321 cgacaccatg cggcaggtgc tcaccacacg gtggggattt cagtctcaac acatcacgat
    19381 gctcacggac caggctgcca ctcgatccgg cattctcgct gcgcttgaac gactcgtgca
    19441 ggacaccggt ccatcagacg tggtctatgt ccactactcg ggccacggat cccaggtcga
    19501 ggacctcaac ggcgatgaaa ccgaggatca tctcgatgaa accctcgtcc cgcacgacgg
    19561 gcggactccg agcgtccccg atatcaccga tgatgaactc gaagccatcg tctccaagct
    19621 gaaggcccgc agcatcttga tcgtcctcga ctcctgccat tccggcacgg caacgcgttc
    19681 cctcgacatc cggacgcgat cggttccaca agatacccgg atagaactct accgaccgtc
    19741 cggggttcac actcgtcagg ttgtgccggt cacggctgcc cgctacgtcc tcatgaccgg
    19801 cgccgccgcc aaccaggagg ccctcgatgg cccggtgggt ggacgttacc acgggttctt
    19861 ctcctattcg ctgtctcgca gtttgggatc ggccgggcta tcagcctcgc cgagagagat
    19921 tttcttcggc gtcgaacggg agatgaagcg gatccaaact cacttcggcc ggatctcgat
    19981 gccggaaccc cagttggagg cgccgccggc gctcatggac gcgcccctgc tgcccatgcc
    20041 ttcggagact ggcaatgaga ctggtacaaa tggaacggcg cggttgccct gggtcgaggt
    20101 gaaggctcac aagggaggcg agaccctcct gttgaacggt ctccagctgg gtgctgcacc
    20161 gggatccact tgggccgtat atccaccgaa cgaaaccaat ttcgcaccgg gaaaatcgct
    20221 cgggctactc acggtgacac aatcccgcgg gaaagacgcc gttaccgcac cgcacgcgac
    20281 agccttcacc atcccgaccg gctcacgcgc catcgaattt ctgccgccgg cctccgtaga
    20341 gggcgtgccc gttcgtctgt tggaaattcc aaatgaccgc cgtgaaaaaa ttgagcaagt
    20401 cctgcgtgaa cagggacgtg aggtccagat cgtcgggccg ggccagcctg cgcaatttct
    20461 ggtggaggtg aaaggcaatc ggttgcagtt gtattcggcc gacgggcttc aactcgtcag
    20521 ctcgttctca ctggacaacg cacagtgggg cgccggactg gcacgggtcc tctcccgatc
    20581 agcgaacgcc tccgaactcc tgacgctcga caatccgtcg gcacaaatca aactggacgt
    20641 gcggattgcc ggggcagcac gccgtcaagc gcgcggcatt gccgtcgtcg ccgacacaca
    20701 gcccgcacag tatcgcatcc ggcatgaagg ggaaccccgc acaccaggca acagcctgca
    20761 gttggaaatc caggcgaccg ctgacagtta tctgaccatc gtcgacgtgg attcggaagg
    20821 tcatctcaat ctgttgtttc ccacggtgca ccagcagccc tcattctacc cggaaggccg
    20881 ggtgcgggcc ggtgacgtgg tcaccattcc cgactcgtta cagtcgggca accatgccgg
    20941 attccattgg gactatgcgc cgccggccgg cactgatacg gtgcgtgtgt ttgcgtcgac
    21001 agatctcgag accgcgcagg ccatccgcca acgcgtcata gccaccactc cccccggccc
    21061 tctcgccaca acgatggtga ccactcgatc gattctctcg tctagcatga cacaccttcg
    21121 gcaggacttg agtcgaatcg cgacgcgggg actttcatcc gtctatgatc cgactccagc
    21181 ggcgttgacg aaccaacctt cgacgccgcc aacccagacg ccaacggctc cgacggctgg
    21241 accttcctcg cctcagccgc ctgtgagtca aaacctctca ccacccatcg ctccatccac
    21301 cgcgcagaca tccgccctca caccggcggc agactgggcc gccacctcgt tgactataga
    21361 ggtcgcacct taaatcctgc ctcttcgata cgtttcaatg gattgatgga tgggaactct
    21421 tcctcacaga agggagtagc gagttctcct gttcgctgcg tcactcgcac tctgatcttt
    21481 gaggatttgg gaggagaccc acggcgtcgt tcaaaacaat atgaagcagg ccggctcaat
    21541 gtgacgctgc ggccgggaac cgcagggcat tcaagatcgc ggcaagacga tagccagcct
    21601 tggctaactg
//
LOCUS       DAOQPD010000065        21218 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1208_length_21218_cov_19.659831, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000065 DAOQPD010000000
VERSION     DAOQPD010000065.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 21218)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 21218)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21218
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1208_length_21218_cov_19.659831"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            41..1078
                     /locus_tag="PK063_13875"
     CDS             41..1078
                     /locus_tag="PK063_13875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="KpsF/GutQ family sugar-phosphate isomerase"
                     /protein_id="HMZ98186.1"
                     /translation="MRRSRSTTSPVTRKTKTSAGRSAAVDASVREGIRVLDIEARAVL
                     DLKARLDERFARAVTLLYECQGKVVISGMGKSGLIGQKIAATLASTGTPSFFLHPAEG
                     VHGDLGMLARRDVLIAISNSGETQEVLQLLPFVKRMNVPVVGMTGKMTSTLSKNSDVT
                     LDVSVDEEACPLGLAPTASTTATLAMGDALAVALLQKRGFKHDDFAQFHPGGSLGRRL
                     LVKVRDLMQHGDHLPRVRADVSGADTILEMTSKKLGLTTVVDAKGSLYGIVTDGDLRR
                     FIQAGGDFSRVTAGDLASRHPKTIGPDELATTAVAQMERFSITALVVIEPPNRLAGVI
                     HLHDLLKHGIV"
     gene            1121..1735
                     /gene="pgsA"
                     /locus_tag="PK063_13880"
     CDS             1121..1735
                     /gene="pgsA"
                     /locus_tag="PK063_13880"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HMZ98187.1"
                     /translation="MGENWKEAGLVLMRSAGQESNINLPNVLTLVRILLIPVFVMLLI
                     DPTPDRALSAAIVFVVAAVTDLLDGYVARKTGQITKLGRLLDPIADKLLVLSALILLV
                     QVDRVSALVAILIIAREVAVTGLRAIAASEGLIMSAEVTGKYKMALQVIAIVLLVLEG
                     TVVETIGNLHLAGIVTLYLSLILGYVSGAQYVWSFWRQVGAKGL"
     gene            1765..2367
                     /gene="plsY"
                     /locus_tag="PK063_13885"
     CDS             1765..2367
                     /gene="plsY"
                     /locus_tag="PK063_13885"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: protein motif:HMM:TIGR00023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HMZ98188.1"
                     /translation="MDSPWLIGVLIIFAYLLGSVPFGVVVSRLLGAVDPRTAGSKNVG
                     FTNVLRVSGKKAGVLTLAGDIGKGWLAGWVATMVLQQETAILGVALASILGHLHSIFL
                     GLKGGKGVATALGAALGVAPWVGLTLMTLWIGAVFLWKYSSGGALFAFGMFPIVALIF
                     HRSWTFIGFACVVSVLIWMRHKDNLIRLWSGTESQIGQSS"
     gene            2397..3035
                     /locus_tag="PK063_13890"
     CDS             2397..3035
                     /locus_tag="PK063_13890"
                     /inference="COORDINATES: protein motif:HMM:NF014171.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA C-terminal domain-containing protein"
                     /protein_id="HMZ98189.1"
                     /translation="MLSFELLARIRKELFLTGSALYETIVAIAERVNRKVHVLRLHGQ
                     ATTILNQTHAIHRQIGQRVAALAAKPAAGIHPVAPSELASLQDAIRTASDRIKGQQAA
                     LQLVERQIRELKVELAHEDLLTMQRELGLRDAAIERVVVARGAPVIGHPIGEFDLPPT
                     TRIAAVFRGPFLLPLSHTMTLRPDDIVILVGLRHDLAHWLPHFQHPAASKSA"
     gene            3125..4528
                     /locus_tag="PK063_13895"
     CDS             3125..4528
                     /locus_tag="PK063_13895"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Do family serine endopeptidase"
                     /protein_id="HMZ98190.1"
                     /translation="MKTPLSCSTLLCLGLILTGSFLGSPLSAVAAADVASTPRTVSPG
                     LRLLEELQTVITDLAEQAKPSVVSIFPIQATGRSRDGGERVPSSTGSGSGVIVDAAGH
                     IITNNHVVGDAAEVEVRLSDKTKLFAQVIGKDPDTDLAVLKVTADHPLPAAHFGDSSG
                     VKVGQWVLAVGNPFGLDRTVTLGVVSGIGRENINLSRYENFIQTDASINPGNSGGPLF
                     DLRGDIIGINTAIINFAQGIGFAIPSNMAKQVMNQLIAKGKVVRAWLGVGLQPLTPEL
                     ASKFGVDENEGVLVNEVFERDPAALAGIKPGDVITKVDGALVDTPNKLSRLVAALDPG
                     STTRVEVVRDGKRLNLQVALSERKDTVVTASLPQSRTDLKLGIDVQDLTAGLAEKFRL
                     NESRGVLISKVDAGSLAQAEGLREGDLIKEVNRVDTGTVGEFTVAVAKVKRGDTILLR
                     VLREGRAFYVVLKPADH"
     gene            complement(4574..6682)
                     /gene="fusA"
                     /locus_tag="PK063_13900"
     CDS             complement(4574..6682)
                     /gene="fusA"
                     /locus_tag="PK063_13900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HMZ98191.1"
                     /translation="MMNVPLTESIRNVAVVSNAGSGKTSLVEALACCAGSLSAPGSIQ
                     AGTTVSDFEPEEIHHRTSLHTSVIRCLYNDHVLNLLDTPGSPSCMAELRAALRVADGV
                     VLVVNAATGVRSDLERLWSFIREAGLPCMVFLNDLDREGTTFATTLEEVTKALDMPAV
                     PLILANGEGGQLGGIVDLLQNCVVTGQADRFQAGPSPIPPEWRDRIDQARRGLIEMVA
                     EGDEALLERYLNDGTLTDAALLEGLRVGVQRGALVPVFGGSALRNVGVQTLLQGLLQL
                     MPSPAARAQIAPVQGVGLSDGEPPMTREPVATAPLSGLVFKTIIDPFVGRLSYVRIYS
                     GTLQADSNVYNATRQVRERGGHVFSIFGKKYTAVSRAVAGDIVAIGKLKDSLTGDTLC
                     DEHAPIRLPGIPLGRPVMSFAIEPKSKADIEKVSVGLHKLIEEDPSLEFVRHMETKEM
                     VLSGMGQLHIDVALEKLHRKYGADVTLHAPKIPYRETIRSVAQAQGKYKKQTGGHGQY
                     GDCWVEVGPLPRGQGFEFQNKIVGGAIPRNFVPAVEKGVVEALHEGPLAGYPAVDVRV
                     SVYDGSYHVVDSSEMSFKIAGSMAVKKAMEAAHPVLLEPLMTVEVDVPAECVGAVLGD
                     LNGRRGRIVSVEASGHIETVKALVPQAEMVSYAASLNSLTGGQGSYVMEFASYEEVPR
                     ELASRIVDEHKAERNGVAAH"
     gene            complement(6793..7509)
                     /gene="radC"
                     /locus_tag="PK063_13905"
     CDS             complement(6793..7509)
                     /gene="radC"
                     /locus_tag="PK063_13905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HMZ98192.1"
                     /translation="MTPKKTGRGIGDWPKTERPRERLLSEGAESLSDAQLLAILLRVG
                     RQDASAVNVGMEVLGRVGGIVGLLHCSTEELCAIPGVGPAKAAQLKAAVEVGKRAVSA
                     PLTTGTRINSSADLFKHYHARLRDLRHEIFAVVLLDAKNQVIRDVTISEGSLTLSIVH
                     PREVFIPAMRASAAGVIFLHNHPSGDPTPSQEDRVLTARLVSAGALLGIQVLDHLIVG
                     DGRYVSFADQGWLGGEASKA"
     gene            7694..7867
                     /locus_tag="PK063_13910"
     CDS             7694..7867
                     /locus_tag="PK063_13910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98193.1"
                     /translation="MECPKCKGMMMLERFSDFFLIFYAWKCINCGAIIDRTISANRRK
                     SLAARDAQPVATR"
     gene            8175..8747
                     /gene="rsmD"
                     /locus_tag="PK063_13915"
     CDS             8175..8747
                     /gene="rsmD"
                     /locus_tag="PK063_13915"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: protein motif:HMM:TIGR00095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HMZ98194.1"
                     /translation="MRVIAGLHRGRRLLGPRGQAIRPTSDRVKEALFSILGERIVGAR
                     VLDLYAGTGSIGIEALSRGAAHVTFVEADREALRLVQSNLRQCGLEQSANVCACQVSQ
                     FFRRGTQWSGPYDVVFCDPPYQLTPELITLAAEWRAGWLAENAIVILEHGRKADVPSI
                     LGPLSQVKRYDYGDTALTRFHLTPKEVHPA"
     gene            8744..9232
                     /gene="coaD"
                     /locus_tag="PK063_13920"
     CDS             8744..9232
                     /gene="coaD"
                     /locus_tag="PK063_13920"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HMZ98195.1"
                     /translation="MKTAVYPGTFDPITHGHSDIIRRGFRMFSRVIVAIAPNPGKHPL
                     FTTKERLEMVRLVTKDLPNLEVTTFEGLLVDFVRTSGAHAILRGLRAISDFEHEFQMA
                     LVNRKLAETVETVFLMPSEEYSYLSSTIIKDVASHGGSLKDFVHPEVARRLQERIRSF
                     KG"
     gene            9229..10422
                     /locus_tag="PK063_13925"
     CDS             9229..10422
                     /locus_tag="PK063_13925"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HMZ98196.1"
                     /translation="MKLAARVGRIVPSPTLSITATAKAMAAQGIDVIDFASGEPDFDT
                     PEPVKAAAEAAIRAGFTKYTPSSGIDELRAAIVDKLKDEQGLQYDKSQILVSCGAKHS
                     LYNVAEALLEAGDELIIPVPFWVSYQDQTLLNDATPVLLQTQERDGYTISQEALEAVI
                     TPRTKAIIVNSPCNPTGATYDRNTLERIAAVALRHDLVIISDEIYEKVLYDGVQHVSI
                     ASLSPEVAARTVVINGVSKAYAMTGWRIGYAAGPKPLLTAMANIQSQSTSNPCSISQK
                     AAVAALRLGNPFTTVMVAEFDRRRRLMVERLNKMPGMTCRMPTGAFYAFPNVSGLLTK
                     RWNNQPIGSAANLATFLLNEAQVALVPGEPFGSDVHIRLSYATSMEAIERGLTRIEAA
                     IRRLS"
     gene            complement(10719..10910)
                     /locus_tag="PK063_13930"
     CDS             complement(10719..10910)
                     /locus_tag="PK063_13930"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98197.1"
                     /translation="MLELLLEAEVVDVVAAGAGAAGVDVEAGLLLVVSDEAGVFALSV
                     PVAAGLSEVSLPPGFILSE"
     gene            complement(11073..11516)
                     /locus_tag="PK063_13935"
     CDS             complement(11073..11516)
                     /locus_tag="PK063_13935"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98198.1"
                     /translation="MLIRSRRAVIGLSMLGFSSMLLLAGCDFWPPALQAQIEQLHSEA
                     QQAAADKALLQNQLNAANKAKEELQIRVEDLTRVNKEKSAMIASLEHTIAAARERAVK
                     AAKAPAAKPAAKTTVKKPVKAPSKATSKSSAKSSTVKKPKSAQLR"
     gene            complement(11565..12212)
                     /locus_tag="PK063_13940"
     CDS             complement(11565..12212)
                     /locus_tag="PK063_13940"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: protein motif:HMM:TIGR00057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HMZ98199.1"
                     /translation="MALVLPFIDKTFDSILPEVERVLAAQGLIALPTETYYGLAVRPS
                     DEVAVRRLIDVKGRPADKPILVLIGGRDQLPTLVSSIPPAAAALMDLFWPGPLTIVFP
                     AATGLSPLLTAGTGTIGVRWSPLATLQRLLKRTGPLTGTSANRSSEPPLDQAASVQHT
                     LGPVLDLILDGGRTPGGSASTIVDACGEPRVLRAGVVSTERIRAALAQRGHTLSS"
     gene            complement(12234..13511)
                     /gene="purD"
                     /locus_tag="PK063_13945"
     CDS             complement(12234..13511)
                     /gene="purD"
                     /locus_tag="PK063_13945"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HMZ98200.1"
                     /translation="MKILVVGSGGREHALVWKIAQSPRKPQIFCAPGNAGIEGLATCV
                     PVKADDIAGLKAFALKEGIDLTVVGPEAPLALGIADEFRKARLKIFGPTKAAARLESS
                     KSFSKDIMAASRIPTAVSKSFEQMDQALAYVDAQPVPIVVKADGLAQGKGVVVAMTRE
                     EAKQAVRDAMEKSVFGQAGQRVLIEEFLDGEELTIMAFTDGNTVVPMIPAQDHKRVGD
                     GDAGPNTGGMGAYAPAPIATAALRDQVTRQVLQPTVDAMARLGCPFQGVLYAGLMIVK
                     GTPYVLEFNARMGDPETEVVLPLLKTDLVDVMEAVVEHRLDELQVEWRQDTAVCVVMT
                     SPGYPGSYETGFPIEGLPAQSGASPIAVFHAGTKREAGQVVTAGGRVLAVAAWAPSLL
                     QARAQVYQAVPGIRFQGRHYRTDIAHRALPRQS"
     assembly_gap    13524..13623
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(13885..15438)
                     /gene="purH"
                     /locus_tag="PK063_13950"
     CDS             complement(13885..15438)
                     /gene="purH"
                     /locus_tag="PK063_13950"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HMZ98201.1"
                     /translation="MASIARALISVSDKTGVVEMAKGLAALGAEILSTGGTAKALRDA
                     GVAVTDVAAYTGSPEILDGRVKTLHPKIHGGLLGRRGVPDHVKQMQQHGIGNIDVVVV
                     NLYPFESTIAKPNCPFEEAIENIDIGGPSMLRSAAKNHEDVLVVVDPSDYTRVLEAVK
                     AGSVTPALRRELAMKVFQHTARYDSLIAGYLEKQVQGSEVKFPAILSLQFERVETLRY
                     GENPHQQGAFYREMQAKEPAVSRGKILHGKAMSYNNFLDSNSALELVKEFDQTAVAII
                     KHNNPCGCALGATPVEAYVKARATDPVSAFGGVIAFNRPVDLAAAKEITSTFVEVVIA
                     PGFAEDALAELKRKKDIRLLDVGPLSKATAEGYDLKKLVGGLIVQDRDLGVIKDIKAL
                     AVPTSRKPTEQEYAACAFAWVVCKHVKSNAIIYGRPGEIVGIGAGQMSRVDSVKLAAM
                     KAQSSVKGCVMASDAFFPFRDGIDAAAEAGITCVIQPGGSIRDPEVTKAVDEHGMAMI
                     LTGMRHFRH"
     gene            15783..16694
                     /locus_tag="PK063_13955"
     CDS             15783..16694
                     /locus_tag="PK063_13955"
                     /inference="COORDINATES: protein motif:HMM:NF012894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HMZ98202.1"
                     /translation="MSRGIIFGVGLFALTLLALICIPRHLPVTSSATGHPSFSAHIEN
                     GHLTLSGAMGSEEAKLAAVARAQELAKNLKLRVTDNLDVLEDGGAAAWEAAVPALLTQ
                     VAALHQHQASLTVSRQTATIKGAASNADAKTKLVHEMSSLLGTAMHVQDQVIVTSAGS
                     ASPSSQPTPTLTATPPTAHASRAQVQASLDEIVRGEHIAFESNSAVLTPKGRAVIDKL
                     IPALKRSPESAIEIGGHTDSYGDPDYNLQLSRTRAESVRQYLADHGVTNRLTAVGYGA
                     SRPLSQDRTRAASKKNRRIEFRVKEER"
     gene            16699..>17857
                     /locus_tag="PK063_13960"
     CDS             16699..>17857
                     /locus_tag="PK063_13960"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98203.1"
                     /translation="MGALILQMIGCLLVAATIGLMMGWLLRSFATSEKRQQLSEIATR
                     LRGREHELDTLNHELKVRTSAVQMLEGKMITSEAALKDLTADLATKVEQLSALQTELR
                     EKGVHLHAAERERDTLRREVEAAENKFKAQQAGFAEMQSQMENAEDVLVSRDQEIATL
                     KTWVEQLAPKDAEIARLRARTEELEPFQERSRRLERELEQDRARATATIQGKDQELAR
                     HQAHIVEMEAELTRLRTQNQEDLTRFTETLQQRDQDIQRLRATVEELEVFRGEVEKKE
                     IQLREAEERRVMDVSEREEEIGALRKRLVEYRVAQRHQAQAKSNNQAEPASHNSSSSR
                     SAGKSRSAQKDDLKQIHGIGPVMERVLNRMGMFTFRQIAEWKDQDVEHMASE"
     assembly_gap    17858..17957
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            18192..18977
                     /locus_tag="PK063_13965"
     CDS             18192..18977
                     /locus_tag="PK063_13965"
                     /inference="COORDINATES: protein motif:HMM:NF024873.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H-like domain-containing protein"
                     /protein_id="HMZ98204.1"
                     /translation="MITSTFCMLPGVGLRTERQFWGQGAWTWDGFLSTRELRGLSAAR
                     KALFDDRITEAQERFTRQDSRYFAKTLAARHQWRLYEWLRERALYLDIEIDSFGQITV
                     VGLYGRGRYTALVRNESLSLLRLKEELSQYDLLVTFCGSTFDLPMLRAHFSDLPLDQP
                     HIDLCGIGRQLGYRGGLKAIERRMGITRLPAIQGFSGDDAVRQWNRWRHQRDEQARDL
                     LLAYNEADCVNLQPLADAFYCRLAVASGLEEIRLQGRTDAVSE"
     gene            complement(19021..20169)
                     /locus_tag="PK063_13970"
     CDS             complement(19021..20169)
                     /locus_tag="PK063_13970"
                     /inference="COORDINATES: protein motif:HMM:NF017727.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NnrS family protein"
                     /protein_id="HMZ98205.1"
                     /translation="MTALFSYGFRPFFLGAAWFAGLAVPAWIVMLSLGIGSTGLAAPR
                     EWHVHEMLFGFLPAVITGFVLTAVPNWTDRPAIQGRELAGLFCLWLAGRVLLAWPWVP
                     PVFAAIVDAAYLLVLAGFLWREISGGKSWSHAPIAVLLSLYAGANLLFHLFALNGTAT
                     DLPERMALGLDLTLLAFIGGRVTPNFTREYLVHARRPEKPARFTHLDMVSIGAVAFAS
                     TFWALLSQDAVAGWFLILAGVLNLVRLSRWYGWFTWREPLVFVLHWGYGWLILALVLL
                     GCAALGVGLPKEDAVHALTTGAVGVMTLGIMTRASLGHTGRQRHADAATIAMYALVTC
                     GAILRVFVAGTGLPTGLVLGAAATCWSGAYLLFALVYGPYLLRPSLDE"
     gene            complement(20347..>21218)
                     /locus_tag="PK063_13975"
     CDS             complement(20347..>21218)
                     /locus_tag="PK063_13975"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98206.1"
                     /translation="QFMSFWPRVEHDTWSVIAIEMAAAVLSMAGLNYIHRSIRDRGLA
                     DAALGAGLVSFFPRRGPAARERIQALKDEQGTGRSVMVLGSSGAGTLVDQVGDLSSVL
                     DKCLEAKILLVNPFNQGARARIQALAHPSCTYPAFREEVRQSIALLKRLKAIGKVVKL
                     KLYADAPLIKLVVFGDYLWLQHYHAELDVQNMPEYVLQRNHQQHGLYTLYAHYFMQRW
                     ESSELPEYDLDTDELVYRSRTGQEIRREPVEIGTRHVAAHPTDTAGVDTREAFQLLHA
                     PGPYLPVRGYDVE"
BASE COUNT         4437 a         6528 c         5969 g         4084 t
ORIGIN      
        1 ttcatgcgct tcattcactc cttgaacggg tattacgtat atgcgacgca gccgctccac
       61 aaccagtccg gtaacgcgca agaccaagac atccgccggg cgttctgccg ccgtcgatgc
      121 gagcgtgcgc gagggcattc gcgtgctcga catcgaagcg cgcgcagtgc tcgatctcaa
      181 ggcccgtctg gatgagcgat tcgccagagc cgtgacgctg ctgtacgagt gtcaggggaa
      241 agtcgtcatt tccggcatgg gaaaatcagg gctcatcgga caaaaaattg cagccacgtt
      301 ggccagtacc gggacaccgt ccttctttct gcacccggcc gaaggagtcc acggcgatct
      361 gggcatgctc gcacggcgtg atgtgctcat cgccatctcc aacagcgggg agacgcagga
      421 agtccttcaa ctgctaccgt tcgtcaaacg aatgaatgtg cctgtcgtcg gcatgacggg
      481 gaagatgacc tccacgttat cgaaaaacag cgatgtcacg ttggatgtgt ccgttgatga
      541 ggaagcctgc cccctgggcc tggctccgac cgccagcacg accgccacgc tcgcgatggg
      601 tgatgccctg gctgtggcct tactgcaaaa acgcgggttc aaacatgacg acttcgcaca
      661 atttcatccc ggcggcagcc tggggcgtcg tttgctcgtc aaggtgcgtg atctcatgca
      721 acatggggat catttgccac gcgtgcgcgc cgacgtgtcc ggggcggaca cgatcctgga
      781 gatgacctcg aagaaactcg ggctgacgac ggtggtcgat gccaagggat cgctatacgg
      841 cattgtgacc gatggagact tgcggcgctt cattcaagcc ggcggcgatt tcagccgggt
      901 cacggccggt gacctggcca gccgccatcc gaagacgatc ggtccggatg aattggctac
      961 gacggccgtc gcacagatgg agcgtttctc catcacggca ctcgtggtca tcgagccacc
     1021 gaatcgcctg gccggggtca ttcacttgca tgacctgctg aaacacggca ttgtataaag
     1081 gaaccttcgc gaacatcgga gacttcgggc gacacagacc atgggagaga actggaaaga
     1141 agcaggactg gtcctgatgc ggtcggcagg gcaggaaagt aacatcaacc tgcccaacgt
     1201 gctgacgctc gtccgcatcc tgttgattcc cgtgttcgtc atgttgctga tcgatccgac
     1261 gccagaccgc gccttgagcg ccgccattgt gttcgtcgtg gcggccgtga cggatctgct
     1321 ggatggctac gtggccagaa aaaccggcca gatcaccaag ctggggcgcc ttctggatcc
     1381 cattgccgac aagctgctgg tgttgtctgc cttgattctg ctggtgcaag tcgatcgcgt
     1441 cagcgcactg gtagccatcc tgattatcgc gcgcgaggtg gccgtgaccg gcttgcgcgc
     1501 gatcgcggcc tccgaaggat tgatcatgtc tgccgaggtc acaggcaaat acaaaatggc
     1561 gttgcaggtc atcgccatcg tccttctggt gctggaaggc accgtcgtgg aaaccatcgg
     1621 caatctgcat ctcgccggca tcgtcaccct ctacctctcg ttgatcctgg gatatgtgtc
     1681 gggcgcacag tatgtctgga gcttctggcg gcaggtggga gcaaaaggtc tgtaggtgaa
     1741 caacccggcg gcacgcactc ggtgatggac agtccctggc tcatcggtgt tctcatcatc
     1801 ttcgcctatc tccttggatc ggttccgttt ggcgtcgtcg tgtcgcgcct gctgggcgcc
     1861 gtcgatccgc gaaccgccgg cagcaagaat gtcggcttca ccaatgttct gcgcgtgagc
     1921 ggcaaaaaag ccggtgtcct gacgctggcg ggggacatcg gcaaaggctg gctggcaggg
     1981 tgggtggcca cgatggtgct gcagcaggaa acggccattt taggggtcgc cctggcgtca
     2041 attctcggcc atttgcactc gatattcctt ggattgaaag gcggcaaagg cgtcgccaca
     2101 gcgttagggg cggcactggg cgtcgcccct tgggtcgggc tcacactcat gacgctctgg
     2161 atcggcgccg tgttcttgtg gaagtattct tccggaggcg cgctgtttgc ctttggcatg
     2221 ttcccgattg tggcgctgat cttccatcgc tcctggacgt ttatcggatt tgcctgtgtc
     2281 gtcagtgtgc tgatctggat gaggcacaag gacaatttga tccgattgtg gagcgggacg
     2341 gaatctcaaa tcggacaatc gagttgacat aatatatctt atcagacatt accgttatgc
     2401 tgtcttttga gctattggct cgcatccgca aagagctgtt cctcaccggc agcgccctct
     2461 acgagacgat tgtcgccatc gcggaacgcg tcaaccgcaa agtccatgtc ttgcgcctcc
     2521 atggccaggc cacgacgatc ctgaaccaga cgcacgccat tcatcgccag atcggacaac
     2581 gcgttgccgc tctcgcagcc aaaccggctg cgggaatcca tccggtagcg ccttccgaat
     2641 tggcctcgct gcaggacgca atccggaccg cctccgaccg catcaagggc caacaagccg
     2701 cgttgcaact tgtggaacgc cagatccgtg agctcaaggt cgagctggct cacgaagacc
     2761 tgttgacgat gcaacgcgaa ttgggtctcc gcgacgccgc cattgaacgc gtggtggtcg
     2821 cccgaggcgc gccggtcatc ggccatccga tcggcgaatt cgacctcccg cccacgaccc
     2881 gcatcgccgc cgtctttcgc gggccgtttc ttctgcctct ctcccacacc atgacgcttc
     2941 gtcccgatga catcgtcatc cttgtcggcc ttcgccacga cttggcccac tggctcccgc
     3001 acttccagca cccggccgca tccaaatcag cctgacccgt ccttcctttc gccgtcacgc
     3061 gaaaatctgg tattctgagg cgtcgccaga gtgcttcggt atcgccctcg gagcttgcct
     3121 caacatgaaa acaccgctgt catgttctac cctgctgtgt cttggactta ttctgactgg
     3181 atcgttcctg ggaagccctt tgtccgccgt ggctgcagcc gacgtcgcct ccacgccacg
     3241 caccgtgtcg ccaggattac gcctgttgga agagctgcag accgtcatca ctgacctcgc
     3301 cgaacaggcc aagccatcgg tcgtcagcat ctttccgatc caggccaccg gccgatctcg
     3361 agacggaggc gagcgggttc ccagctcgac cggatcgggg tcaggcgtca tcgttgatgc
     3421 cgccggccac atcattacca ataatcatgt ggtgggcgac gcggcggaag tcgaggttcg
     3481 cctctcagac aaaacgaagt tgtttgcgca ggtgatcggt aaggatccgg acaccgacct
     3541 ggccgtactc aaagtcaccg ccgaccatcc cctgcccgcg gcccatttcg gtgactcgtc
     3601 cggcgtgaag gttggccagt gggtgctggc ggtcgggaat ccgttcggcc tggatcgcac
     3661 cgtaacgctg ggggtggtca gcgggatcgg acgtgagaac atcaatctct cccgctacga
     3721 aaatttcatt cagactgacg cgtcgatcaa tccaggcaac tccggcggcc cgctgtttga
     3781 tctccgtggg gatatcatcg gcatcaatac cgccattatc aattttgcgc agggcatcgg
     3841 tttcgccatc ccgtccaaca tggccaagca ggtcatgaac cagctgatcg cgaaaggcaa
     3901 agtcgtgcga gcctggttgg gggtcgggtt acaaccgctg acgccggaac tggccagcaa
     3961 gttcggggtg gatgagaacg aaggggttct ggtcaatgaa gtgttcgagc gggatccggc
     4021 ggcgttggcc ggcatcaagc ctggagacgt catcacgaag gtcgatgggg cgctcgtgga
     4081 tacgccgaac aaactgtctc gcctcgttgc cgcattggac cccgggtcaa cgacgcgtgt
     4141 cgaagtcgta cgcgacggga aacgcctcaa tctccaggtc gccctgagcg aacgcaagga
     4201 tacggtcgtg accgcctcct tgccgcagag ccggaccgat ttaaaattgg gcatcgatgt
     4261 gcaggacttg acggccggcc tggcggaaaa gtttcgattg aatgaaagtc gcggcgtgct
     4321 gatttcaaag gtggacgcag gaagcctcgc ccaggcagaa ggattgcggg aaggcgacct
     4381 gatcaaggag gtcaaccgcg tggacaccgg cacggtcggg gaatttaccg tggcggttgc
     4441 caaggtcaaa cgcggcgaca cgattcttct gcgcgtctta cgggaaggac gtgcgttcta
     4501 tgtggtgctg aaaccagccg atcactaacc gatttcaaca aggccgcatc gcgtcaggtg
     4561 gggacgtggc ccgtcaatgg gccgcaaccc cattgcgctc cgctttgtgt tcgtcaacaa
     4621 tccgggacgc cagctcccgg ggcacctctt catagcttgc aaattccatc acataactgc
     4681 cctgcccgcc ggtcagcgaa ttcaacgagg cggcatagct gaccatttct gcctggggta
     4741 cgagagcctt caccgtttct atatggccac tggcttccac cgaaacaatc cgtccacgcc
     4801 ggccgttgag atcacccagc accgcgccga cgcactccgc cggaacgtcg acctctacag
     4861 tcatgagcgg ttcaagcaga accggatggg ccgcttccat ggcttttttc accgccatcg
     4921 atccggcgat tttgaacgac atttcagagg aatccaccac atggtatgag ccgtcgtaga
     4981 cggacacccg cacatccacg gcgggatatc ccgccaatgg gccttcgtgc agtgcttcca
     5041 caaccccctt ctcgacggcc ggcacaaaat tacgcggaat ggcgccgccg actattttgt
     5101 tctgaaactc aaatccctgg cctcgcggga gcggaccgac ttccacccaa cagtccccgt
     5161 attgtccatg tccgccggtt tgtttcttat attttccctg tgcctgcgcc acgctgcgaa
     5221 tcgtttcgcg atagggaatt ttcggcgcat ggagcgtcac gtcggcgcca tacttgcgat
     5281 ggagtttttc cagcgcgaca tcgatatgca attgtcccat tccgctcagc accatttctt
     5341 tcgtttccat gtgccggacg aactctaagc tggggtcttc ttcgatcaac ttgtgcaacc
     5401 cgacactcac cttttcgata tcagctttgg atttgggctc gatggcaaac gacatcaccg
     5461 ggcgaccaag tggaatcccg ggcagccgga tcggagcgtg ctcatcacac agcgtgtcac
     5521 ccgttaagct atctttcagc ttcccgatgg ccacaatatc gcccgccacc gcccgtgaaa
     5581 cagccgtgta ctttttcccg aagatcgaaa acacatgccc cccgcgctcc cgaacctgtc
     5641 tcgtcgcgtt gtacacattg ctatccgcct gtaacgtgcc tgaatagatc cgcacgtacg
     5701 acaggcgccc gacaaacgga tcgatgatgg tcttgaatac cagtcccgag agaggggcgg
     5761 tcgcgaccgg ctccctcgtc atgggcggct caccatcaga gagtccgact ccctgcacgg
     5821 gtgcaatctg agctcgggca gccggagacg gcatgagttg aagcaggccc tgtaacaatg
     5881 tctgcacccc cacgttgcgc aacgccgatc ccccgaacac ggggaccagc gcgccgcgct
     5941 ggacgccgac ccgcaatccc tccaacaagg cagcgtccgt caatgtccca tcgttcaggt
     6001 accgttcaag caacgcctcg tcgccttcag cgaccatctc gattaagccg cgccgggcct
     6061 ggtcaatccg atcgcgccat tcgggtggaa tcggagaggg ccccgcttga aatcgatcgg
     6121 cctgccccgt cacgacacag ttctgcaaca aatccacgat gccccccaat tgcccgccct
     6181 ccccattcgc aaggatcaac gggacagcag gcatgtccag cgctttcgtc acctcttcga
     6241 gcgtcgtggc gaatgtcgtc ccttcccgat ccaaatcatt caggaacacc atgcagggaa
     6301 ggccggcctc acggatgaac gaccagaggc gttccaggtc actgcgaact cccgtcgccg
     6361 cgttcacaac gagcaccacg ccgtccgcaa cacgcaatgc cgctcgcagt tccgccatgc
     6421 aacttgggga gcccggggtg tcgagaagat tgagtacgtg gtcgttgtag aggcaacgaa
     6481 tgacgctggt gtggagggat gtccggtgat ggatttcttc cggctcaaaa tcggagacgg
     6541 tcgtgccggc ctgaatagac ccgggagcgg aaaggctgcc tgcgcaacag gcgagcgctt
     6601 cgactaatga ggttttgcct gatcccgcat tcgataccac agccacattc ctgatggatt
     6661 cggtgagggg aacattcatc atgacctcct ccggtagtgg gcggccgctg gggcctggtt
     6721 agagagagac ctgtgggcga caccatcctt tcttcatccg tacgaattcg tcccgtggtg
     6781 acaggcagtc cgtcatgctt ttgaggcctc tccgccaagc catccctggt cggcgaaact
     6841 gacataccgg ccgtctccca cgataaggtg atccaggacc tgaatgccca gcagcgcccc
     6901 cgctgaaacg agcctggccg tcagcacacg gtcttcctgg cttggagtag ggtctccgct
     6961 ggggtgatta tggagaaaaa tgactccggc ggctgacgca cgcatggcgg ggatgaagac
     7021 ttcccgcggg tgcacgatgc tcagcgtgag actgccttct gaaatcgtca cgtcgcgaat
     7081 gacctgattt ttcgcatcca gcaatacgac agcgaaaatc tcgtgacgca ggtcccgtaa
     7141 gcgtgcgtgg taatgcttaa agagatccgc gctggaattg attcgcgtgc cggtcgtcaa
     7201 tggcgccgaa acagctcgtt tgcctacctc caccgctgcc ttcaattgcg cggccttggc
     7261 cggccctacc ccgggaatcg cgcagagttc ttcggtgctg cagtgcagca gcccgacaat
     7321 gccaccgacg cgccccagca cctccatgcc gacgttgacg gccgacgcgt cctgccgtcc
     7381 cacgcgcagc agaatcgcca ataattgcgc atcagacagg ctttcagccc cctcactgag
     7441 caatcgttcg cgcggccgtt cagtttttgg ccaatctccg attccacggc cggtcttttt
     7501 tggtgtcatg gcggcttcct acgacaaaaa aatgtcagcg tgcacgattt tgtgccggag
     7561 acttgacgcc tggcgcatgt catatatggc actttcgatg cgtaacatat tgaaattaaa
     7621 agattttaca ttttggtgca gctcttgctt gagagcagac acagctgtaa acgtcaacac
     7681 ccaggaggaa accatggaat gtccgaagtg caaaggtatg atgatgttgg aacggttctc
     7741 agacttcttc ctcattttct acgcctggaa atgcatcaac tgcggagcca tcatcgaccg
     7801 aaccatttcg gccaatcgta gaaagagcct cgccgctcgc gacgctcaac cggtggcgac
     7861 ccgctaaacg cggagccctc gctctgttcg ctctgtgtga tggggtggtg tgacggccca
     7921 ggattggcca cctcctcagc ccgcgtgaac cgagtattgg tgtcgcccga ttatagcgag
     7981 cctccttttg cgcgtcaaag cgcgtacact cctccttgac gtctacagcg ctccccgccc
     8041 cgcggcgggg agaagacctt tccggctcac ggccgctcct cgccgcctcc agtcaccttg
     8101 accccttcaa aaacgctgtg ttacattctc tcacttctta gccagagacg aatggctctc
     8161 acctgaatac gatcatgcgc gtcatcgctg ggctgcatcg gggccgacgg ttgctgggtc
     8221 ccaggggaca ggccatccgc ccgacatccg accgagtcaa agaagccctc ttttctatcc
     8281 ttggcgaacg tatcgtgggg gcgcgcgtat tggatctcta tgcggggacc ggctcaattg
     8341 gcattgaagc gctgagccgc ggggcggcgc atgtgacctt tgtggaagct gatcgcgagg
     8401 cgctacgcct ggtccaatcg aatctgcggc aatgcgggct ggaacaatcc gccaatgtgt
     8461 gcgcctgtca ggtgagtcag ttttttcgtc gcggcacgca atggtcgggt ccttatgacg
     8521 tggtcttctg cgatccaccc tatcaactca cacctgaatt gattacgctg gcggcagaat
     8581 ggcgtgccgg ttggctggcg gagaacgcca tcgtcatcct ggaacatgga cgaaaagcgg
     8641 acgtgccctc catcctggga ccactttcgc aggtgaagcg ctacgactat ggcgacactg
     8701 cactgacccg ctttcacctt acgccgaaag aagttcaccc ggcatgaaga ccgccgtcta
     8761 tcccggcaca ttcgatccga tcacgcatgg gcacagtgat atcatccggc gcggattccg
     8821 gatgttctcg cgggtcattg tggccatcgc cccaaacccg ggtaagcacc cgctgttcac
     8881 cacgaaggaa cgattggaga tggtgcgcct cgtcaccaaa gatcttccca acctggaggt
     8941 caccaccttc gagggactgt tggtggattt tgtgcgcacc agcggcgccc atgctattct
     9001 gcggggactg cgcgcgattt ctgatttcga gcacgagttt caaatggcac tggtcaatcg
     9061 aaaactggcg gaaaccgtgg agacggtctt cctcatgccc agtgaagaat attcctatct
     9121 ctcttccacc atcatcaagg atgtcgccag ccacggcggg tcactgaaag actttgtgca
     9181 cccggaagtg gcacggaggc tccaagaacg aattcggagt ttcaaaggat gaaactggca
     9241 gcccgtgtcg gacgaattgt gccctctcca accctgagca ttaccgccac cgcaaaagcc
     9301 atggcggctc aaggtatcga cgtcatcgat tttgcctccg gcgaaccgga ctttgatacg
     9361 ccggaaccgg tgaaagccgc ggccgaggcc gccattcgag caggctttac gaagtatacg
     9421 ccgtcgtcag ggatcgacga actgcgtgcc gcgattgtcg ataagttaaa agacgaacag
     9481 ggacttcagt atgacaagtc ccagattctg gtgtcctgcg gcgccaaaca ttccctctac
     9541 aacgtggcgg aagcgttgtt ggaggcgggc gatgaactga ttatcccggt ccccttctgg
     9601 gtgtcctacc aggatcaaac cctgctgaac gatgccaccc cggtcctgct tcagacacag
     9661 gagcgggatg ggtacacgat ttcgcaagaa gccctggaag ccgtcatcac cccgcgcacc
     9721 aaagcgatta tcgtcaacag cccgtgtaat cctaccggcg cgacgtacga ccggaacact
     9781 ctggaacgca tcgccgccgt cgctttgcgt catgacctcg tcatcatttc agacgagatt
     9841 tacgagaagg tgttgtacga cggcgtgcag cacgtcagca tcgccagcct gagcccggaa
     9901 gtcgcagcac gcacagtggt catcaacggt gtttcgaaag cctatgcgat gaccggttgg
     9961 cgcatcggct atgccgcggg tccgaagccg ttgctgacag cgatggcgaa catccaaagt
    10021 caaagcacct cgaacccctg ctccatttcg caaaaagccg ccgtggcggc gctccgtttg
    10081 ggaaacccct ttaccactgt gatggtggcg gaattcgatc gtcggcgacg cctgatggtc
    10141 gagcgcctga acaaaatgcc tggtatgacc tgtcgcatgc cgaccggagc attttatgcg
    10201 ttccccaatg tgagcggcct gctgaccaag cgatggaaca atcaacccat cggctcggcc
    10261 gcgaacctgg cgaccttttt gctcaacgaa gcgcaggtgg cgttggtgcc tggtgaaccg
    10321 tttggaagcg acgtccatat ccggctctcc tatgcgacct cgatggaagc gatcgaacgc
    10381 gggttgaccc gcatcgaagc cgccattcgc cggctgtcgt gatcaacagg atctcgacac
    10441 ctcggcccct tgactgctct cgacacgatg ttatcagggg agaggtcttg cagctgacgg
    10501 atcgagccaa tcaagaccga gtgacgccct aggatcagag gaggaagacc cgtgccaatc
    10561 tatgagtatc aatgttccag ctgtgcgcat cgcttcgagg tgaagcagag catcaaggat
    10621 gaccccatca aggaatgcgt acgctgcggc aaagaagtga cgaagctgat ttcgccccct
    10681 gccattatgt ttaaaggcag cggttggtat atcaccgact actcggacaa aatgaaaccg
    10741 gggggcagcg atacctccga caagccggca gctaccggca cagacaaggc gaaaaccccg
    10801 gcctcgtcgg ataccacaag cagcagcccc gcctccacgt cgacgcctgc agcgcctgcg
    10861 ccggccgcga cgacatccac tacttcggct tcgagcagca gctcgagcac atccagcccc
    10921 agtgcagcgg ggtctcagtc gtcagcccca tcctccagta aatcgtgaga aggctcttgc
    10981 cttcacgcga tgagagtggt cgatcggctc gatctttctg acgtgggacc aaccgaacct
    11041 gctggccggg ctgtacgctg acttgagcag gcttatcgaa gctgggcaga tttcggtttt
    11101 ttgacggtcg aggatttggc agaggatttc gacgtcgctt tcgatggcgc tttgaccggc
    11161 ttcttcaccg tcgtttttgc ggcaggcttg gccgcaggag ccttggcggc cttcacagcc
    11221 cgctccctcg ctgcggcaat cgtgtgctcc aaactcgcaa tcatcgccga cttttcttta
    11281 ttcacccgcg tgagatcttc gactcgaatt tgcagctctt ctttggcctt attcgccgcg
    11341 ttgagctgat tctgcaagag tgccttatcc gccgcagcct gttgcgcttc cgaatgtaat
    11401 tgttcgattt gggcctggag cgccggcggc caaaagtcac atcctgccag cagcagcata
    11461 ctgctgaacc cgagcatcga cagtcctatc accgcgcgac gtgaacgaat gagcataagt
    11521 ggtcctcccg tgtgggtgaa ttatacccac aacgcaccat caaatcatga tgaaagtgtg
    11581 tgtccccgtt gagcgagggc cgcacggatc cgctccgtcg acaccacccc cgctcgcagc
    11641 acgcgcggtt cgccacaggc atccacgatg gtggacgctg atccacccgg cgtgcgtccg
    11701 ccgtccagaa tcagatcgag aaccggcccg agagtgtgct gcacagacgc ggcctgatcg
    11761 agaggcggtt cagatgaccg attggcgctg gtccctgtca gcggaccagt gcgcttgagc
    11821 agacgctgca gcgtggccag cggtgaccat cgaacgccga tcgtgccggt tcccgccgtc
    11881 aacaacggtg acaagccggt cgcagcagga aatacgatcg tcaagggacc cggccaaaac
    11941 agatccatca gcgcagcggc ggccggagga attgaggaca ccaacgtcgg tagctgatcg
    12001 cggccaccga tgagtacgag aatcggcttg tcggccggcc ggcctttgac gtcgatcagg
    12061 cggcgcaccg ccacctcgtc gctggggcga accgccaatc cataataggt ttcagtcggc
    12121 agtgcgatca gcccctgcgc ggccaggaca cgttcgacct cagggaggat gctgtcgaag
    12181 gtcttgtcga tgaagggaag gaccagagcc atgtcaggcc tgtcgagcgc ggttcaagac
    12241 tggcgtggaa gggcgcggtg ggcgatgtct gtgcgatagt ggcgtccctg gaagcgaata
    12301 cccggcacag cctgatagac ctgtgcccgc gcttgcagta aagacggagc ccaggccgcg
    12361 actgccaaca cgcgcccccc ggccgttacc acctgccctg cttcccgttt ggtcccggcg
    12421 tgaaataccg caatgggcga cgccccagac tgcgccggca aaccttcaat agggaacccg
    12481 gtctcatagg aaccgggata ccccggtgag gtcatcacca cacagacggc ggtgtcctgc
    12541 cgccattcaa cctgcagctc gtcgagacga tgttcaacca ccgcctccat cacgtcgacc
    12601 agatcggtct tcagcaaggg caacacgact tccgtttccg gatctcccat acgtgcattg
    12661 aattccagca cgtagggagt ccccttcacg atcatgaggc ccgcgtacag cacgccttgg
    12721 aaaggacagc ccaaacgggc catcgcatcc acggtcggtt gcagtacctg ccgcgtcacc
    12781 tggtcgcgca gcgcagccgt cgcaatggga gccggagcgt aggcgcccat gccaccggta
    12841 ttgggtccgg catcaccgtc gcccacccgc ttgtgatcct gcgcggggat catcggcacg
    12901 acagtgtttc catccgtaaa tgccatgatg gtcagctcct cgccatcgag aaactcttca
    12961 atcaacaccc gttggccggc ctggccgaag acggatttct ccatggcgtc gcgcaccgcc
    13021 tgtttggctt cctcgcgcgt catcgccacc actacgccct tgccctgcgc gaggccgtcg
    13081 gccttcacca caatcggcac gggttgagca tccacatacg ccaacgcctg atccatctgc
    13141 tcgaagcttt tcgagaccgc cgtgggaatc cggctggccg ccatgatgtc cttcgagaag
    13201 cttttgctgg attccagccg tgccgcagcc ttggtgggac cgaagatctt caaacgtgct
    13261 ttcctgaact catcggcaat gcccagcgcc agcggcgctt caggaccaac gacggtcaga
    13321 tcaatgccct ccttgagagc aaaggccttc agcccggcaa tatcatctgc cttgaccggc
    13381 acacaggtcg ccaggccttc gatgccggca ttgcccggcg cgcaaaagat ctgcggcttc
    13441 cgcggactct gggcaatttt ccagaccagg gcatgttccc gaccaccact gccgacgacc
    13501 agaattttca cagctcaacc tttnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13621 nnngggcatg ttcccgacca ccactgccga cgaccagaat tttcacagct caacctttag
    13681 ttgaaatgac gatagacgga tctcacacag aattgaccgc agacttcaag aaccgcggac
    13741 agccatcctc gctctgccga ggatgctcaa acaggttttc caacaaggcc gcaggcgaga
    13801 aaaaaccgga ggcgtagcct ctgggctacg ttgaggattt tttcgagccg agaacgaagt
    13861 tggaaacctg tttcagcatc cgatctagtg gcggaagtgg cgcatgcctg tgagtatcat
    13921 cgccatcccg tgttcatcta cggccttggt cacctcgggg tcacgaatag acccgccggg
    13981 ctgaatcaca caggtgatac cggcttctgc cgcggcatcg atgccgtccc ggaacgggaa
    14041 gaacgcgtcg gacgccatga cacagccctt cacggacgac tgcgctttca tcgccgccaa
    14101 cttcaccgaa tccacccggc tcatctgtcc ggcgccgatg ccgacgattt caccaggccg
    14161 accgtaaatg atggcattcg acttcacatg tttacagacc acccaggcaa atgcacaggc
    14221 cgcatattcc tgctcggtgg gcttgcgtga ggtcggcaca gcgagtgctt tgatatcctt
    14281 gatcacgccg agatcccgat cctggacgat caatccaccg accagcttct tgagatcata
    14341 tccttccgcg gtcgccttgc tgagcgggcc gacatccagc agacgaatgt ccttcttccg
    14401 cttgagttcc gccagcgcat cctcggcaaa acccggcgcg atgacgactt ccacaaacgt
    14461 cgacgtaatc tccttcgccg ctgccagatc gaccggccga ttaaacgcaa tcaccccgcc
    14521 gaacgccgac acaggatccg tcgcgcgcgc tttgacgtag gcttccacgg gcgtggcgcc
    14581 gagggcgcag ccgcagggat tgttgtgctt gataattgct acggcggtct ggtcaaactc
    14641 cttcacgagt tcgagcgccg aattggagtc gagaaaatta ttgtacgaca tggctttgcc
    14701 gtgcaggatc ttgccgcgtg acacggccgg ctccttggcc tgcatctcac gatagaaggc
    14761 cccctgctgg tgcggatttt caccgtagcg cagcgtctcc acccgctcga actgcaagga
    14821 gagaatggcg gggaacttca cctcgctccc ttgcacctgc ttttcaagat acccggcgat
    14881 cagactgtca tagcgcgccg tgtgctgaaa gaccttcatc gccagttcgc ggcgcaatgc
    14941 cggcgtgacg gaaccagcct tcacggcctc caatacgcgg gtgtaatcag acgggtcgac
    15001 cacgacgagc acatcctcat ggttttttgc ggcggagcgc aacatggagg gaccgccgat
    15061 gtcgatgttc tcgatcgcct cctcaaacgg acaattgggc ttggcgattg tcgattcgaa
    15121 gggatacaga ttcaccacga ccacatcgat gttgccgatg ccgtgctgct gcatctgctt
    15181 gacgtggtcg ggaacgcccc gacgccccag caaaccgccg tgaattttcg gatgcagcgt
    15241 tttcacgcgg ccgtcgagaa tctccggcga ccccgtatag gcagccacat ccgtcaccgc
    15301 cacacccgca tcacgcaagg ctttggcggt tccgcccgtg gacaatattt ccgcgccaag
    15361 ggctgccaac cctttggcca tctcaacaac tccggtcttg tcagaaacac tgatcagtgc
    15421 ccgcgcaatg ctggccatga tgaactcctt caactatgga tatcgtgtgg gtgggatcac
    15481 attggacgaa aaaacgccgt gacaatagca gatgcctcga cgccactgca agccgatcga
    15541 gtatgccatc accgcatcag cgctgtggca gaatccgatg agggaatcag gaggacgtcc
    15601 gctacccaga atccaggcta gcatgagtcc cagcgatgtg atacccttcg caattcgtaa
    15661 tcgagcagcc ggcgctgcct aaacaggaaa tcaagtaaca ctcgaagtct tcaaccactc
    15721 cacatcctgt ggcgttcgac gccgcagcga ggcctcgtcc ccgaggcgat aagggctggc
    15781 gcatgtcgcg cggaattatt ttcggcgtag gactctttgc actcacatta ttggcgctca
    15841 tttgtatccc tcgacacctg ccggtgacgt cgtcggccac ggggcatccc tcgttcagtg
    15901 cccatatcga gaacggtcac ctgacacttt ccggggcaat gggaagcgaa gaggccaaac
    15961 tcgccgccgt cgcacgtgcg caggaactcg ccaagaacct caagttgcgt gtcaccgaca
    16021 atctcgacgt gctggaggac ggcggagcgg cagcatggga agccgcagtg cctgccttgc
    16081 tcacgcaagt ggcggccctg caccaacacc aggccagcct cactgtctcg cgccaaacag
    16141 cgaccatcaa gggcgcggcc tcgaacgcgg acgccaaaac gaaactcgtg catgagatga
    16201 gctcgctgct cggcaccgcg atgcatgtgc aggaccaggt aatcgtcacc tcggccggct
    16261 ccgcctcccc gtcatctcaa ccgacgccga cactgaccgc cacccctccg acggcgcacg
    16321 cctctcgcgc gcaagtgcag gccagcttgg atgagatcgt gcgcggagaa catatcgcgt
    16381 ttgagagcaa cagcgccgta ctcaccccta aaggacgagc ggtgatcgac aagctcattc
    16441 ccgcgctcaa gcgctcgccc gaatcggcca ttgaaatcgg cggccatacc gattcctatg
    16501 gcgacccgga ctacaatctc cagttgagcc ggacgcgagc cgagtcggtc cgccaatatc
    16561 tggccgatca tggagtgact aatcgattga ccgccgtcgg ctatggcgcc tcccgtcccc
    16621 tgagccagga ccggacgcgc gccgcctcca aaaagaaccg gcggattgaa tttcgtgtga
    16681 aagaggaacg gtgaacgtat gggagcctta attctgcaaa tgatcggatg cttactggtg
    16741 gcggcgacca tcgggctcat gatgggctgg ctgttgcgga gtttcgccac gtcggagaaa
    16801 cgccagcagt tatccgaaat tgccacccgg ctccgcggtc gcgaacacga attagacacc
    16861 ctcaaccatg agttgaaagt gcgcacctcc gccgtccaga tgctggaagg caagatgatc
    16921 acctccgaag cggcgctcaa agatttgacc gccgatctgg ccacaaaggt cgaacaactc
    16981 tcggcgctgc agaccgaact ccgtgaaaaa ggggtgcacc tccatgcagc cgagcgcgaa
    17041 cgggatacgc ttcgccggga agtcgaggcc gccgaaaaca agttcaaggc gcaacaagcc
    17101 ggcttcgccg aaatgcaatc gcagatggag aatgccgaag acgtgttggt cagccgggat
    17161 caggaaatcg ccacactaaa aacctgggtg gagcaacttg cgcccaagga tgccgaaatt
    17221 gcccgcctgc gggcgcgcac cgaagaactg gaaccgttcc aggaacgaag ccgtcgattg
    17281 gagcgggaac tcgaacaaga tcgcgcgcgg gctacagcta ccattcaggg caaggatcag
    17341 gagctcgccc gtcaccaggc acacatcgtt gagatggaag cagaactcac tcgcctgcgg
    17401 acacaaaacc aggaagacct cacgcgcttc accgaaacgc tgcagcagcg ggatcaggat
    17461 attcaacgcc tccgcgccac cgtcgaagaa ttggaggtgt tccgtggaga ggtggagaaa
    17521 aaggagattc aactccgcga ggcggaagaa cgccgggtga tggacgtcag tgaacgggaa
    17581 gaagaaatcg gcgcgctacg caagcggctg gtcgaatacc gcgtcgccca acggcaccag
    17641 gcgcaggcga aatcgaacaa ccaggctgag ccggcctcgc acaactcctc cagctcccgg
    17701 agtgccggaa aatcacggtc tgcccagaaa gacgatctca agcagattca tgggattgga
    17761 ccggtgatgg agcgcgtgtt aaatcgcatg ggcatgttta catttcgcca gatcgccgaa
    17821 tggaaggatc aagacgtcga acatatggcg tcggagcnnn nnnnnnnnnn nnnnnnnnnn
    17881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17941 nnnnnnnnnn nnnnnnnttt cgccagatcg ccgaatggaa ggatcaagac gtcgaacata
    18001 tggcgtcgga gctcaacacc ttcccggatc gcatccgcca cgacaattgg atcgcgggcg
    18061 ccaaggaaca acattttctg aaatacggtg aggaactgta gtccgtcctg atcagatcgt
    18121 ccgttcccct cctcgctgtt attccagccc cttcctgctg cacgctgtac cgacccgttc
    18181 ggagacccta catgattacc tccaccttct gcatgctccc cggagtcggc ctgcgcacgg
    18241 aacgacagtt ctggggccaa ggcgcctgga cgtgggatgg ctttctgtcg acccgcgaac
    18301 tacgcgggct cagcgcggct cgaaaagccc tcttcgacga ccggatcacc gaggcgcagg
    18361 agcgattcac gcgacaggat agccgctact ttgcgaaaac cctggcggct cgccatcagt
    18421 ggcggttgta tgaatggtta cgggaacggg cgctctatct cgatatcgaa atcgattcgt
    18481 tcggacagat cacggtggtc gggttgtatg gccggggacg ctataccgcg ctcgtcagaa
    18541 acgagtcgct gagcctgctt cgcctgaaag aggaattgtc acaatatgat ctcctcgtga
    18601 cattctgcgg atcgacgttt gatcttccga tgttgcgggc gcacttttca gacctgcccc
    18661 tggaccagcc gcacatcgat ctctgcggca tcggccggca attggggtat cgcggggggc
    18721 tcaaagccat cgaacgccgg atgggcatca cccgcctgcc ggcgatccaa ggcttttccg
    18781 gagatgatgc cgtccgccaa tggaaccggt ggcggcacca acgcgatgaa caagcaaggg
    18841 atctcttgct cgcgtacaac gaagctgact gcgtgaactt acagcctctc gccgatgcct
    18901 tttattgccg tctggccgtg gcgtccgggc tcgaggagat tcggcttcag ggcaggacgg
    18961 atgctgtaag cgagtagaac atccttcctg agggtgattg ccttactcaa cctgccttca
    19021 ctactcatcc agactcggac gcaagaggta cggcccatag accaacgcga acagcagata
    19081 cgcgccgctc caacaggttg cggccgcacc aagcacgaga ccggtaggca gaccggtacc
    19141 agccacgaac actcgcagaa tcgctccgca ggtgaccagg gcatacatgg cgatcgtcgc
    19201 agcatcggca tgccgctggc gtccggtatg tcccaagctg gcgcgggtca tgatgcccaa
    19261 ggtcatgaca cccactgccc ctgtggtgag cgcatgcacc gcatcctcct tcggcaggcc
    19321 gacgcctagc gcggcacatc cgagcaggac gagcgccaga atgagccacc catatcccca
    19381 atgcagcaca aacacgagcg gctcccgcca tgtgaaccag ccataccacc gcgacaaccg
    19441 gacgagatta aggacgccgg cgaggatcag aaaccagccg gccacggcgt cctgggacaa
    19501 caacgcccag aatgttgagg cgaacgcaac tgccccgatc gacaccatat cgagatgagt
    19561 aaaccgggcg ggtttctccg gccggcgagc gtgcaccaga tactcacggg taaaattcgg
    19621 cgtcacgcgc ccgccgatga aggccagcaa ggtcagatcc agccccaacg ccatgcgttc
    19681 gggcagatca gtcgcggtcc cattgagcgc gaacagatga aaaagcagat ttgcgcccgc
    19741 atagagactg agcaggacgg cgatcggcgc atgactccag ctttttcctc ctgaaatttc
    19801 gcgccaaagg aatcctgcca acaccagcag ataggccgca tcgacgatgg ctgcaaagac
    19861 cgggggtacc cagggccatg ccagcagcac acggcccgcg agccacaggc agaacaggcc
    19921 cgccaattcc cgtccctgga tggccggacg atctgtccag ttcggcaccg ccgtcagcac
    19981 aaacccggtg atgaccgccg gcaaaaatcc gaacaacatt tcgtgcacat gccattcgcg
    20041 aggtgccgcc aggccggttg aaccaatccc gagcgacaac atcacgatcc aggcaggaac
    20101 agccaggccc gcgaaccagg cggcgccgag aaaaaacgga cggaagccgt aggaaaataa
    20161 tgcggtcatt gacgacactc cgcttccttt cgtcttacga cttatcatcc ttcaccctct
    20221 cgtggatacg accggccggc gaggcattgc catggccgcc ctagtcatac cacagcgccg
    20281 aggagtgagc catgacaagg gagagcagcg agcacgcgat gaacggacgg atgaatgcgg
    20341 cgactcctat tcgacgtcgt atccgcgaac cggcaggtac gggcccgggg cgtgcaacaa
    20401 ttgaaacgct tcacgcgtat cgactcccgc cgtatccgtg ggatgagcgg caacgtgtct
    20461 ggtcccgatt tccaccggct cccgccggat ttcttgaccg gtccggctcc gatataccag
    20521 ctcatcggta tccagatcgt attcaggcaa ctcggagctc tcccaccgct gcatgaagta
    20581 gtgggcgtac aacgtataca agccgtgctg ctggtggttc cgctgcagga catattctgg
    20641 catgttctga acatccagct ccgcatggta atgctgcaac cagaggtagt cgccgaagac
    20701 caccaacttg atcaacggag catcggcgta gagcttcagc ttcaccacct tcccgattgc
    20761 cttgagacgc ttgagtagcg cgatactctg ccggacctcc tcgcgaaagg ccggataggt
    20821 acaggaaggg tgagccaacg cctggatccg cgcccgtgcg ccctgattaa atggattcac
    20881 caggagaatc ttcgcctcta ggcatttgtc gaggaccgac gacagatcac ccacttggtc
    20941 caccagagtc cccgcgccgc tggatccgag caccatcacg gaacggccgg tgccctgctc
    21001 gtcttttaag gcctgaatgc gctctcgcgc tgccggcccg cgccggggaa agaatgagac
    21061 gagaccggca ccaagtgcgg catcggcaag tcctcgatcc cgtatactcc gatggatata
    21121 gttcaagccg gccatcgaca gtacggcggc agccatttca atcgcaatca cagaccaggt
    21181 gtcatgttcc acccgcggcc agaacgacat gaactgcc
//
LOCUS       DAOQPD010000066        20676 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1255_length_20676_cov_22.640949, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000066 DAOQPD010000000
VERSION     DAOQPD010000066.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 20676)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 20676)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20676
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1255_length_20676_cov_22.640949"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..497
                     /locus_tag="PK063_13980"
     CDS             <1..497
                     /locus_tag="PK063_13980"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98207.1"
                     /translation="ARDLEKADIHTITRNLDSLVLEVTKLVKDTNEQALSSRTGRVLA
                     EFQETARQTRRLVESPEIRAMVSDAAGTVQGARQLIADLSEASKQIKIASEQFPGVFA
                     RLERTVQRIDRLVSNKSQDIEDTVENLRVMSENLREITDNAKRYPAQVLLGEPPPRAG
                     ATKR"
     gene            544..1122
                     /locus_tag="PK063_13985"
     CDS             544..1122
                     /locus_tag="PK063_13985"
                     /inference="COORDINATES: protein motif:HMM:NF015823.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-type transport auxiliary lipoprotein family
                     protein"
                     /protein_id="HMZ98208.1"
                     /translation="MFVLGGCVNLSKSYPEKHSYILEAVHSGEMRASIPGTVLKVRKF
                     RVSPTSEGKELVYRTSDARYEGDFYNEWFVPPNAMLTQQIMNWLTSAGLFQYVMDSSG
                     PLPATHMLEGTLTALHGDYRATPARAVLAVQFLFLHEASAQGEVLWHREYRKEVDIME
                     QKPEALVSGWNEALRLILSALDEDLTRTLRRQ"
     gene            1540..2904
                     /locus_tag="PK063_13990"
     CDS             1540..2904
                     /locus_tag="PK063_13990"
                     /inference="COORDINATES: protein motif:HMM:NF017760.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HMZ98209.1"
                     /translation="MSLVSLLRATFQGLRDDERTQGTLEVGEQLSSKRNVRWLWTGEL
                     ISQLGDGLNRPAILWFVYDLTGSAVKMTFIGVLQTIPPLVLGPVIGVYLDRLSADWKL
                     RVMISLDLARGALLAWLATLSILGMLTLPTLYTFVFLIALAAMPYGPALNSTIPSLVQ
                     ASRLTAANAAIQSTATLGLLCGPAISGATVAFLGVGYVLYANAATFLLAAFSKMPIRV
                     NSEAPSPSRSGTSSGWINELAAGFRLVFVEQRIIFRVALLGALFTLASTGFIFLLPII
                     TKNILSGGPMFLGVIWSALGLGMIFMSVLLMSSARRTLIDHLLLISAGPVIEGLAIVG
                     LAAVDSLVAALGLVIVIGAGTALVMPMITAFIQATAPQETRARALTIFGTITMVSAMA
                     GMTAFSWAADHLGSRIALVVLGVVQMMAGVIGIMFTQSSEFQTNLASRSNDHPSSKSD
                     TGIT"
     gene            complement(3166..3543)
                     /locus_tag="PK063_13995"
     CDS             complement(3166..3543)
                     /locus_tag="PK063_13995"
                     /inference="COORDINATES: protein motif:HMM:NF014870.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MGMT family protein"
                     /protein_id="HMZ98210.1"
                     /translation="MGECSLGSILVAKSERGICALFLGDDPDALARELQDQFPRATLI
                     GGDADFDQLVAKIVGFVEAPSLGLDLPLDVRSTAFQGRVWQALRRIPAGLRMSYREIA
                     EHLARKCLWKLIVSGRHRGMGRD"
     gene            3575..3952
                     /locus_tag="PK063_14000"
     CDS             3575..3952
                     /locus_tag="PK063_14000"
                     /inference="COORDINATES: protein motif:HMM:NF013718.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HMZ98211.1"
                     /translation="MTKFAVGRERPNEGRGTHSFDPFHEFDRSFPSSHTARAFAVASV
                     FADRYEQPIPLIAYGTAAFISVSRVYLNEHFASDVVAGAVLGFVIGKVLSWRHKDENR
                     RWTVLPYVPDARGGLGMTFSCSF"
     gene            4039..5403
                     /locus_tag="PK063_14005"
     CDS             4039..5403
                     /locus_tag="PK063_14005"
                     /inference="COORDINATES: protein motif:HMM:NF013283.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BamA/TamA family outer membrane protein"
                     /protein_id="HMZ98212.1"
                     /translation="MARILSALLLSVLCAINGCTSAQVTQTHASQPNAFQAEGKKQEQ
                     SQEARSPEERLRKEKPQEERDEEDTVLSAIAAAPEYLVKGLAYPFKKFGIYYERTDLM
                     NRLMDLFYNDERTGGVFPRMAVGGALSSGIGFTAFHQDLFHQKKEVRARYLYATRGNQ
                     AADFAYRDPSLFGSKFMLDLDVFWLNFDNGFFFPGGNRAAENGKTKYDLNQLSQNARL
                     SYMVAPNLKASLLGRILFTDAGPSSRTPTTPPTVPGIDTYMQGAAVEPSLTYDSRDNP
                     FRPSTGLYIDTGFTYTNQLNGDQFRYMGYWVDVQRYIPVFRGDRVLVIRAYLSKLDSL
                     DGKSIPFYELNLLDLNNGLRGFDRGRWQDKGALLYNLEWRYPVWKDVEGTIFLDLGQV
                     FGDYKDLQPKLFQYSAGGGFRFVTSRSFAFRVQLAASNDGLLALFRGDLEFVRHRGTV
                     LGGF"
     gene            5463..7253
                     /locus_tag="PK063_14010"
     CDS             5463..7253
                     /locus_tag="PK063_14010"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98213.1"
                     /translation="MRDWNWRRRISAFSCDGVAAWFLCALALSVIGCYNRVVLQEPVV
                     WEVNDRRPISEPQEETIGQWALWDGTDKMVFYRIGQLFNLGRSMRDLGAWVGLADPIE
                     AQNVNAFDEVPNSTWFTNRQFFSRRSEEELTAGPTTDRGAPDTAGPWTAIAAKASLGS
                     TPGFVIRDQKNDVYLIKFDPPLYPEMTTASEMITPRFLHAAGYNVPEHYLVYFDPAKI
                     RIDPKAKFRGKYHVPRPMQEQDITAILDRIPHRPDGTIRAMASKYLADVPKGPFLYEG
                     KRPDDPNDRILHENRRELRGFRILAAFVNHTDTKAANALDTYDPETRYLTHHLIDFSS
                     TLGADNADPQFPRFGNEYFFDFGTVGHSTIAVGSYVRPWEIPLEMHYPAVGYFESLYF
                     DPPRWRPTYPNPAFLRMTLRDAYWGAKIVTSFTDEDIDAIVHTGRYTDARAERYVADV
                     LKARRDKIGRYYFNLINPLDRFTIDTEFDEQVLVFENLALSRGYAPAPHALYRYSISK
                     YVPNWFDTSVIQETLVQSPKIRLDKAFLEAWGKHTADGRATEEERPIAAVRIQTSYDD
                     GSHWGKRVVVYLREHPGTRRMTIVGLERET"
     gene            7275..10043
                     /locus_tag="PK063_14015"
     CDS             7275..10043
                     /locus_tag="PK063_14015"
                     /inference="COORDINATES: protein motif:HMM:NF015194.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005471 - ATP:ADP antiporter activity
                     [Evidence IEA];
                     GO_process: GO:0006862 - nucleotide transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Npt1/Npt2 family nucleotide transporter"
                     /protein_id="HMZ98214.1"
                     /translation="MNFVPILQKLVDIRSGEYRKTVLMFLYIFLLLLSFVIIKAVRDA
                     LFLVRLGPEQLPYIYILVAVIVGVVAWIHAKLSARLRLDVLIRGTLLIVVANLLIFWW
                     LFRFGWPSLYYVFYIWAAAIGLLTMSQYWLLANSVFNAREAKRLFGLIGAGSILGGLV
                     GGVVTARAVTWIGTEGLLIIAATGYLLCGGLALIVGRAAVPAARPSGNASGMSAQAEA
                     AAHSEESILTTIRNSPYLITIAGLIGIGEIVVMLVDYQFKVIATQLFPSKNDLTGFMG
                     IFSALVSASSFLVQVFFTGRILRSLGLGLALLCLPVGLLFGSVAIAVVPGLISAVMAK
                     LTEGSLRFSINKASLELLYLPLPWAIKAKTKPFIDPASERVAGGIGGLILIVATSILS
                     LSTAQISFVTIGLLSLWVPLALAGQRQYVDSLRLALERRRLDLTFPILNLSDRRTVDL
                     LIRHLLDSDDAGTCYVLRLLEQADVKPYIPAFKQLLTSRSPEVRAAVIRLLSEIREPS
                     LVPALTDVLGDQEMEILVGAVRFLDAHPGSSGAKLEEWMASTDPRLAAAAIVGLLNDP
                     AQRLGARAEQALRSMIQAHGPQGEIRRREAAKALGWIHPEATASDALIRLLQDDSIEV
                     VITAIKSAGRIQRREFVSPLVALLVRKETKGEAKTALVGYGSKILGGLADLLEDDNER
                     MELRRTLPSLLAEIGGERAIAILLHNLNQPDRLLRYQVVKALNRIRAHDPNLEPEPEL
                     IDASLTSELRHHYELLLLFHSPSLVEDSQGGRLLKKALQERLDHQLEMVFRLLALRFP
                     VSDIRDAYAGLTVDDARLRAIATEFMDNLLPSHLKRYLIPIIDNWPSDAVVEVGRQFV
                     SINGSTREELILYLLKGTDLWLKTCAIYLAGEWKLSSLLSELRQAADDSGHLIRETVH
                     LALEQLND"
     gene            10049..10465
                     /locus_tag="PK063_14020"
     CDS             10049..10465
                     /locus_tag="PK063_14020"
                     /inference="COORDINATES: protein motif:HMM:NF012257.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030551 - cyclic nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HMZ98215.1"
                     /translation="MLTTIEKVLLLQGVDILVDTETENLAKIAAIAREVRFEEGATIF
                     EEGEPSNAFYIVLEGTVSVRKGSKEIGLVKDKETVGWVNLLEQTPRTVTLVALTGTTF
                     LKIEREGLFDLLADHFDIVRGILKRLSRIINQLLDR"
     gene            10941..11327
                     /locus_tag="PK063_14025"
     CDS             10941..11327
                     /locus_tag="PK063_14025"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98216.1"
                     /translation="MTGRLSEGTDEFHSPHGLDGPDHFYTFALAQRTRMEIAVAANTS
                     HWSDAVGLTRAAWQPALYLLSADGAMLKEGHVFRAGVTSLFPAEFEPGTYYLVVDSSI
                     REWSRGDGYYRLYVGFNEEVMGPLVP"
     gene            11394..11861
                     /locus_tag="PK063_14030"
     CDS             11394..11861
                     /locus_tag="PK063_14030"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98217.1"
                     /translation="MLIKELLRLQATQTYLRAIVGGDFNFEHHSPEYQELLVAGLRDT
                     HMIASPRTDLYSSDPNQNTIVHQEELTMPPSLRQAMTNLPEAEQQRMAEGYQDGMGQA
                     RRIDYLFHMGKGPHLPNECLRQTLLGESAALSTPSGSDHFGVLNTYILDPSQR"
     gene            12018..12470
                     /locus_tag="PK063_14035"
     CDS             12018..12470
                     /locus_tag="PK063_14035"
                     /inference="COORDINATES: protein motif:HMM:NF024852.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HMZ98218.1"
                     /translation="MSGKTKPTDPSAKMYYNDRWSKGARANTNGVKQAGIGCLLFVGG
                     AGSLEVKPGVQSVDTPEFLKDWKQGALATREVLNLLRKELSLDWSFLSPSADLSPGQR
                     TGNFRLGKDQLLVDAKGQSRISVEDYALAMIDEAEAPHHIRQRFTVGY"
     gene            12551..13300
                     /locus_tag="PK063_14040"
     CDS             12551..13300
                     /locus_tag="PK063_14040"
                     /inference="COORDINATES: protein motif:HMM:NF009385.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HMZ98219.1"
                     /translation="MNNHTLKGKVAGAGAKNLGGLLSREFAKGGAKVVVHYNSDTTKP
                     NADDTVKAIKDIGGEAYAVQGDLTKPTNIAALFKSAKDRFGGIDIAVNNVGKVLGKPI
                     VDTTEAEFDSMFDINAKAAYFFIKEAGTNLNNNGKIITIVTSLLAAFTDGYSTYAGGK
                     APVEHFTRAAAKEFGPRGISVTAVGPGPMDTPFFYGQEMSERVAFHKSQALNGNLTKI
                     EDIVPIVRFLATEGWWVTDQTIFANGGYTTR"
     gene            13596..13958
                     /locus_tag="PK063_14045"
     CDS             13596..13958
                     /locus_tag="PK063_14045"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98220.1"
                     /translation="MSLLLDRILAADFEVPDVELLRSPTVVQTNNVAQYLHGTNRKDP
                     DDLTQDFPNIAPPWPNFFVEFAMPSTICEVTPEGSQMMQWEGPKTFGLHWMAGRRGSY
                     DFGLQQSLFKTLSESTNP"
     gene            14482..15393
                     /locus_tag="PK063_14050"
     CDS             14482..15393
                     /locus_tag="PK063_14050"
                     /inference="COORDINATES: protein motif:HMM:NF012798.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HMZ98221.1"
                     /translation="MSEKLMTQTQWTQLCDNVVLACASQHSQRAYRASASMYRAWVAR
                     TKLMLLSKATVLRYRDYLLLTKKLAPKSINLHLTVLRRLAQEGMAEQVLDTSTAMAIL
                     RIPMVPNRGVRAGVWLPREQAQRILSGPNVLTIVGKRDYLVLMLILRCGLRRAEIAQL
                     AVTVVREHEGRWVLANLRGKGKRLRTLPLPGVVKNAWDRWVEAAGIESGRVIRAINRH
                     GRVWGKGVTEDTIWRIVGRYAQLALGKHVAPHDLRRTFGRLCYALTKDMREIQQLYGH
                     SSVMTTEKYLGVEPHLVDSVTDRLGLS"
     gene            15992..16885
                     /locus_tag="PK063_14055"
     CDS             15992..16885
                     /locus_tag="PK063_14055"
                     /inference="COORDINATES: protein motif:HMM:NF012798.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HMZ98222.1"
                     /translation="MAAFLQERAPTIADTTVATYARKLSTFHEWWCNHEPSLPFSETL
                     ATRYARWLATHSTRSQASQGLHLSAVRQWACFLLAAGHLSINPLAGVSGPPRARWLRH
                     RLLTRTDLQGLLKQFAVTTLVGQRDYLLAALMIRTGARESELAVANIGDLTEYGEEGS
                     LLLLHSKGKAKQEPVVVRPDLSTKLWAYLRQRYPDGRFPPHDPLLTNHHPSSRGERMT
                     TRGMRKQLKAAFREAGLAEPHVTALSLRLSGGALAYRKGASPSELKKTMRHESIQTTQ
                     VLIDQVNRIRFGAERYLDDIQ"
     gene            complement(18900..19331)
                     /locus_tag="PK063_14060"
     CDS             complement(18900..19331)
                     /locus_tag="PK063_14060"
                     /inference="COORDINATES: protein motif:HMM:NF013970.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family
                     toxin"
                     /protein_id="HMZ98223.1"
                     /translation="MVIDASVALAWCFPDEQSPYADKVLQELDGCSVLVPSVWALEIT
                     NGLLVGERRRRIGQSDILRFIDLLDALSPQEVSVPINAHFHALLPLGRGYGLSAYDAA
                     YLHTAIRTEAELATADDALEKAARTAGVPIMCTSHLRKPRR"
     gene            complement(19337..19582)
                     /locus_tag="PK063_14065"
     CDS             complement(19337..19582)
                     /locus_tag="PK063_14065"
                     /inference="COORDINATES: protein motif:HMM:NF014643.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system
                     prevent-host-death family antitoxin"
                     /protein_id="HMZ98224.1"
                     /translation="MDTIGAFEAKTHLSALLERVSKGETITITRHGVPAAKLVPVQGD
                     VGRLPHAALLEGMRELRKRVKPGAMPVKDMIEEGRRR"
     gene            complement(20173..>20676)
                     /locus_tag="PK063_14070"
     CDS             complement(20173..>20676)
                     /locus_tag="PK063_14070"
                     /inference="COORDINATES: protein motif:HMM:NF012798.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HMZ98225.1"
                     /translation="GKGQQTKESFVNLMPEVYGRLQRYLEARGPVLPREPLFARHHDK
                     LTSHLAQVRSKPGGGEASTLAPNERLRLTTRAIQLRIAGAMTRCGLRDVTRPGEASSL
                     ESRRRRQRRVTPHSLRHTAATEAARTESPFKVQAMLDHKDIRTTQKYFHAIDRLEEGA
                     EYAITRY"
BASE COUNT         4476 a         5644 c         5968 g         4588 t
ORIGIN      
        1 tagccagaga tttggaaaaa gccgacatcc acacaataac cagaaatctc gatagtcttg
       61 tgcttgaagt gacgaaattg gtcaaagaca caaatgagca ggcattgagt agccggacgg
      121 gacgagtgct ggcggagttt caagagacgg cacgacaaac gcgccggctt gtggagagcc
      181 ctgaaatcag agccatggtt tccgatgcgg ccggcacggt gcaaggagcg agacagctca
      241 tcgccgattt gtcagaggca tcgaaacaaa tcaagatcgc atccgaacaa ttccccggcg
      301 ttttcgcccg gttggagcgt acggtgcagc gaatagacag gctcgtgtcg aataagagtc
      361 aagatatcga ggacacagtg gagaatctgc gagtcatgtc agagaatctt cgggaaataa
      421 ccgacaatgc gaaacgatat cccgctcaag tgttgttggg cgaacctccg cctcgggcgg
      481 gggcgacaaa gcgataaccc gtccgggata gcactgccgc atttcatcgg catctgcctt
      541 gtcgtgttcg tacttggcgg ttgcgtcaat ctcagcaaga gttatccgga gaagcactcc
      601 tatattctgg aggcggtaca ttcaggcgag atgcgggcct ccattcctgg aaccgtcctg
      661 aaggttcgaa aatttcgagt ctcgccaacc tctgaaggaa aggagttggt gtatcgcacg
      721 agcgatgcac gttacgaagg agacttttac aacgagtggt ttgtcccgcc caatgcaatg
      781 cttacccaac agatcatgaa ctggctgaca tcggccggcc tgtttcagta tgtcatggat
      841 tcgtcggggc cattgcctgc cacgcatatg cttgagggga ccctgacggc actgcatgga
      901 gattatcgtg caacccctgc cagggctgtt ctggctgtcc aattcctctt cctccatgag
      961 gcgtccgctc aaggagaagt tctgtggcat cgagagtatc ggaaagaagt ggacatcatg
     1021 gaacagaagc ccgaggcact cgtgtcgggt tggaatgagg ctcttcgact tatcttgagc
     1081 gctcttgatg aagacctcac tcgaacactc cggcgtcagt gacgcgtggg cagataaagc
     1141 cgttacggcc gtaattggga cgatcttacc ttcacgatcc aggaaggtca gccaacggac
     1201 tggcggcaag tgatcgatac gagtctcccg agcccggagg actttcgcag cccgggagaa
     1261 gaacaaaccg ttccatccct tcactacaga gtgacggcat ggtcaatcga ggtcttgttg
     1321 cggaaggcag tgtgagggag tagtaggagg cacgaccttg cggatcggca tggcagcagg
     1381 ccacgacgga ttgaagttga agcgaaacgt agaaggacct ttcagagaag gcctcctatg
     1441 cgctcgaggt cgtgcgccaa agcgagagaa tccttttcat agataccccg gttatgccgg
     1501 aatagtaggt cttacttcct aactctcttg ggtaaagcta tgtccctcgt gagcttgctg
     1561 cgcgcgactt ttcagggcct ccgggatgac gaacggacac agggaactct tgaggtcggt
     1621 gagcagctga gctcgaagag aaatgtgcgg tggctttgga ctggggagct aatttcccaa
     1681 ctcggggacg gcctcaatag gccggcgatc ctgtggttcg tgtacgatct cactggttct
     1741 gctgttaaaa tgacgttcat tggtgtcctt cagaccatcc cgcccttggt tctcggccca
     1801 gttatcggtg tgtatctcga tcgtctgtcc gccgactgga aacttcgcgt gatgatctca
     1861 ctggatctcg cgcgtggtgc acttttggcg tggctcgcga ccctctctat tctcggtatg
     1921 ctgaccttac ccacattgta cacattcgtt tttctgatcg cccttgctgc aatgccgtat
     1981 gggccggcct tgaactcgac cattccctct ctggtacaag cttcgcgcct gaccgctgca
     2041 aatgcggcaa tacaaagcac ggcaacgctc ggcttgttgt gcggacccgc gatcagcggc
     2101 gccacagttg ccttccttgg tgtggggtac gtcctgtacg ccaatgccgc cacctttctg
     2161 ctcgccgctt tctctaagat gccgatacgc gtaaactcag aagcaccgag cccgagccgg
     2221 agtggaacat ccagtggatg gatcaatgaa ctggcagctg gattccggct tgtgtttgtt
     2281 gagcaacgaa tcatttttcg agttgccctg ttaggcgccc tcttcactct cgcatcgaca
     2341 ggcttcatct ttctccttcc catcatcacc aagaacattc tttctggagg gccgatgttc
     2401 cttggggtga tatggtcggc ccttggcctc ggcatgatat tcatgtcagt gctgttaatg
     2461 tcgagcgctc ggcgaacact catcgatcat ttgttgctga tatcggcggg gccggtgatt
     2521 gaagggttgg ccattgtggg gctcgcagcg gttgacagct tggtggcggc gcttggtctc
     2581 gtgatcgtca tcggtgccgg aacggctctt gtcatgccga tgatcacggc ctttattcag
     2641 gcaacagctc ctcaggagac tcgtgcaaga gcgttgacga tcttcggcac tatcacgatg
     2701 gtctccgcca tggcgggcat gacggccttc agctgggcag ctgatcatct gggaagtcgt
     2761 atcgcactcg ttgtgcttgg agtcgtgcaa atgatggccg gtgtgatcgg catcatgttt
     2821 acgcaatcct cggagttcca gacaaatctc gcgagtcggt ccaatgatca tccgtcaagc
     2881 aaatcggaca ccggtatcac ttgaccccgt ttcgtcgctg ctccagcggg ttctgaatag
     2941 gacacaactt tccagtaatc ggagacagag acgaacattg aagtgggaac agcaggttgt
     3001 cggtgtctgc atccagagga aaagtagagg ggattgagac gaccgtgagg tgatcggcat
     3061 catccgggcg gcgaaatctg gcgcaagagg cgacaggccc tatcaggcgc tcgcggggca
     3121 gtaagagcga ttgtttccgc aagtaccgaa agacccattg aacggctagt cacgacccat
     3181 accccggtgc cggccggaca cgataagttt ccagagacac ttgcgcgcca gatgctcggc
     3241 gatctcgcgg tagctcatcc tcaggcccgc aggaatcctt cgcaatgctt gccacactcg
     3301 cccctggaac gccgtgctcc gcacatccaa cggcagatcg agaccgagcg acggcgcttc
     3361 gacgaagccg acgattttcg cgacgagctg gtcgaagtcg gcatcacctc cgatgagagt
     3421 ggctcgagga aactggtctt gtaactcgcg cgccagcgcg tccggatcgt cgcccagaaa
     3481 aagggcgcaa atcccgcgct cgctcttggc caccaggatc gaccccagcg agcactcgcc
     3541 cacggcgaac cagatctccg tccgggcgcc aggcgtgacc aagtttgcgg tagggcggga
     3601 gcggccgaac gaggggcgtg gcacgcactc attcgatccg tttcatgaat tcgatcgatc
     3661 ctttccctcg agtcataccg cgagggcatt tgccgtggcg agcgtatttg ccgatcgcta
     3721 cgagcaaccg atcccgttga tcgcctatgg cacggcagcg ttcatcagcg tctcacgggt
     3781 gtatctcaat gagcactttg cctcggatgt cgtcgcgggt gccgtcttgg gttttgtgat
     3841 cgggaaggtc ctgagctggc gccataagga cgagaatcgg cggtggaccg tgctccctta
     3901 tgttccggac gccaggggtg ggttggggat gacgttcagc tgctcattct gactggaagc
     3961 cggctcaacg gcctggcgat gccgatcgac atgcgatcgt aaagattgcg gaaccggcta
     4021 tgggagcttc ttagacaaat ggcaagaata ctttccgcgc ttctcctcag cgtcctgtgt
     4081 gcgatcaatg gctgtacttc cgcacaggtc acgcagacgc acgcttcgca gccgaacgca
     4141 tttcaggcag aaggcaagaa acaggagcag tctcaagaag cgcggtctcc agaagagcgg
     4201 cttcgaaagg agaagccgca agaggaacgg gatgaggaag acacggtgct ctccgcaatc
     4261 gcggccgctc cggagtacct cgtgaaagga ttggcttatc cattcaagaa gttcgggatc
     4321 tattacgagc gcaccgacct gatgaaccgc ctcatggatt tgttctacaa cgatgagcgt
     4381 accggtggag tgttcccgcg catggccgtg ggcggggcgt tgagcagcgg catcggcttc
     4441 accgcgttcc atcaagacct cttccatcag aagaaggagg tgcgggctcg ttacctgtac
     4501 gccaccagag gcaatcaggc tgcagacttc gcctaccggg atcccagctt gttcggctcg
     4561 aaattcatgc tcgatctcga tgtcttttgg ctgaacttcg acaacggatt ttttttcccg
     4621 ggaggcaatc gggccgcgga gaacggcaaa acgaagtatg acctgaacca gttgtcgcag
     4681 aatgccagac tcagctatat ggtggcgccc aacctcaagg cgtcccttct gggcaggata
     4741 ttgttcacgg acgcagggcc ttcaagccga actcccacga ccccaccgac cgtgccaggg
     4801 atcgatacct atatgcaggg agcggcggta gagccaagcc ttacctatga ttcaagggat
     4861 aacccatttc gtccgagcac cggtttgtac atcgacacag ggttcaccta caccaaccaa
     4921 ttgaacgggg atcaattccg ctacatgggg tattgggtcg acgtccagcg atacatcccg
     4981 gtctttcgtg gagaccgggt attggtgatt cgggcgtatc tctccaaact ggattccctg
     5041 gacggcaagt cgatcccgtt ctatgaattg aatctcctcg atctgaataa cggactgcgg
     5101 ggatttgatc ggggacgctg gcaggacaag ggagcgctcc tctacaatct cgaatggcgc
     5161 tatcccgtgt ggaaagacgt tgagggcacg atttttctcg atctagggca ggtattcggc
     5221 gactacaagg atctgcaacc caagttgttt caatattccg ccggaggagg attccgattt
     5281 gtcacgtcca ggagttttgc ctttcgagtc caattggcgg caagcaatga cggcttgctg
     5341 gccttgttcc ggggagactt ggagtttgtt cggcatcgcg gcactgtgct cggtgggttc
     5401 tgaactgcga tgcaatcaga gctgcaaggc gagatagatc cggcgatccg aggaggcgag
     5461 agatgaggga ctggaactgg aggcggcgga tcagtgcttt ctcttgtgat ggcgtcgccg
     5521 catggtttct ttgcgcgctc gccctgtctg tgatcggctg ctataaccgg gttgttttgc
     5581 aagaaccggt cgtatgggaa gtcaatgatc ggcgccccat ctccgaaccg caagaggaaa
     5641 ccatcggtca gtgggcactc tgggatggta ccgacaagat ggtgttctat cggatcggtc
     5701 aactcttcaa cctcgggcga tcgatgcggg atctgggcgc ttgggtcggg ctggccgatc
     5761 cgatcgaggc ccagaacgtc aatgccttcg atgaggtgcc gaactccacc tggtttacga
     5821 atcgccagtt tttctcgagg cgctccgaag aggaactgac ggctggcccg acgacggatc
     5881 gcggcgctcc cgataccgcg ggaccgtgga cggcgattgc cgcgaaggca agcctcggtt
     5941 cgacgccggg gttcgtcatc cgggatcaga aaaacgacgt ctatctgatc aaatttgatc
     6001 ctcccctcta tccggagatg accacggctt ctgaaatgat cactccgcgg tttctgcacg
     6061 cggccgggta taacgtaccc gagcattatc tggtctactt cgatcccgcc aagatcagga
     6121 tagacccgaa ggccaagttc cgtgggaagt atcatgtccc gaggccgatg caggaacagg
     6181 atatcacggc cattttggac cggattcctc accggccgga cgggaccatt cgcgccatgg
     6241 caagcaagta cctggcggac gttccgaaag gtccgttcct ctacgaagga aagcgtcccg
     6301 atgatcccaa tgatcggatc cttcatgaga atcgacgtga gttgcggggc tttcgcatcc
     6361 tcgcggcctt cgtgaatcat accgatacca aagcggcgaa tgcactcgat acatatgatc
     6421 ccgagacacg ctatctcacg catcacctca tcgacttttc ctcgacccta ggagccgaca
     6481 atgcggatcc gcagtttccc cggttcggca acgagtattt ctttgatttt ggtaccgtcg
     6541 ggcattcaac aatcgctgtc ggcagctacg tcaggccgtg ggaaattccc ctggagatgc
     6601 actatccggc cgtagggtac tttgaatcct tgtatttcga tccgccgcgg tggcggccca
     6661 cctatccgaa cccggccttt ctccgcatga cattgcgcga tgcttactgg ggcgccaaga
     6721 tcgtgacgtc ctttaccgac gaggatattg acgcgattgt ccataccgga aggtatacgg
     6781 atgccagggc agaacgctac gtcgcggacg tgttaaaagc aaggcgcgat aagatcggac
     6841 gctactattt taacttgatc aaccccctcg accgctttac tatcgacacc gagttcgatg
     6901 agcaggtact ggtcttcgag aatctggccc tctcccgcgg ctatgcgccg gctccgcacg
     6961 cgctttaccg ttattccatc agcaaatacg tgccgaactg gtttgacaca tccgtgatcc
     7021 aggaaaccct ggttcagtcg cccaagatcc gtctggacaa agcgttccta gaagcctggg
     7081 gaaaacacac cgccgatggc cgcgcaacgg aggaggagcg gccgatcgcg gcggtgagaa
     7141 ttcaaaccag ctatgatgat ggatctcact ggggcaagcg tgtcgtcgtg taccttcgag
     7201 aacatccggg gaccaggcgc atgacgattg tcggtctgga gcgggaaacc tagattgttc
     7261 gcatggcgaa ctcgatgaac ttcgtcccaa tcctccaaaa actagtcgat atcaggagcg
     7321 gtgaatatcg gaaaaccgtt ctgatgttcc tctatatctt tctcctgtta ctctcgtttg
     7381 tgattatcaa ggcggtgcgc gatgcactct ttctggtcag gctgggccct gagcagctcc
     7441 cctatattta cattctggtg gccgtgatcg tcggagtggt agcctggatc catgcgaagc
     7501 tttcggcgcg ccttcgcctc gatgtgctga ttcgcgggac gctgctcatt gtcgttgcca
     7561 acctgctcat cttctggtgg ctttttcggt tcggctggcc ctcgctttac tatgtgttct
     7621 acatctgggc agccgccatc ggtcttctca cgatgtccca atattggctc cttgccaatt
     7681 ccgtcttcaa tgcgagagag gccaagcgac tcttcggcct catcggtgcc ggatccatcc
     7741 tcggaggcct cgtcggggga gtcgtgaccg cgagagccgt gacttggatc gggaccgagg
     7801 gcctgttgat tatcgccgcg acggggtacc tcttgtgcgg cggtttggcc ttgatcgtgg
     7861 gtcgtgctgc tgtgccggcg gctcgtcctt ccggtaacgc atccggaatg tccgctcaag
     7921 cggaagcggc cgctcattcc gaagaatcga tcctgacgac gatcaggaac tctccgtatc
     7981 tcatcacgat tgccggtttg atcgggatag gagagatcgt cgtgatgctc gtcgattatc
     8041 aatttaaggt gatcgccacg cagttatttc cgtccaagaa cgacctaacg ggcttcatgg
     8101 gaatcttttc ggcattggtc agcgcctcgt cgttcctcgt gcaagtgttc ttcaccggaa
     8161 gaatactgag gagcctgggg cttggtttgg ccctgctgtg cctccctgtc ggcttactct
     8221 tcggttctgt cgccattgcc gtggtcccgg ggctcatctc ggcagtcatg gcgaagctca
     8281 ccgagggcag tttgcgattc tcgatcaaca aagcgagtct ggagctgttg tacctgccgc
     8341 tgccatgggc aataaaggcc aaaaccaagc catttatcga cccagcttcc gagcgtgtcg
     8401 caggaggcat cgggggcctc attctgatcg tcgccaccag catcctctcg ctgtcaactg
     8461 cacagatcag cttcgtgacc atcggactgc tcagtctctg ggtcccattg gccctggccg
     8521 gccagagaca atacgtcgat tctttgcgcc tcgccttgga gcggaggcga ctcgatctga
     8581 cattcccgat tctgaatctc tcagatcgac ggaccgtcga tctgttgata cgccacctcc
     8641 ttgattcgga cgatgccggg acgtgctacg ttctcaggct cctggagcag gcggatgtca
     8701 agccgtacat cccggccttc aaacaattgc tcaccagtcg gtctcctgag gtccgggccg
     8761 cggtgattcg cctcctcagc gaaatcaggg aaccctctct cgtgccggcg ctgacagacg
     8821 tgcttgggga tcaggaaatg gagattcttg tcggcgccgt gcgctttctt gatgcacatc
     8881 ccggctcttc gggcgcgaag ctcgaagaat ggatggcgag caccgatccg cggctcgcgg
     8941 ccgcggcgat cgtcggtctc ctgaacgacc cggcgcaaag gttgggtgcg agggctgaac
     9001 aggcgctccg ctcgatgatt caagcccacg gccctcaagg cgagattcgt cgccgggaag
     9061 ccgccaaagc tttgggttgg attcatcccg aggcgactgc ttcggatgcc ctgatacggc
     9121 tgttacagga tgactcaatt gaggtcgtga tcaccgcaat caagagcgcc ggcaggatac
     9181 agcgcagaga atttgtttct ccgcttgtcg ctttgctggt gagaaaggag acgaaaggcg
     9241 aggccaagac cgccctagtc gggtatggct ccaaaattct ggggggtctt gccgatttgc
     9301 tcgaagatga caacgaacga atggagctgc gacgaacgct tccctcgctg cttgccgaga
     9361 taggagggga aagggcaatc gccattctcc tgcacaatct caatcagccc gaccgattgc
     9421 tccgttatca agtcgtgaag gcgctcaaca gaattcgcgc gcatgatccg aatttggagc
     9481 cggagccgga actcatcgac gccagcctga ccagcgaact acggcaccat tatgagctgc
     9541 tgctcctctt tcacagtcct tcgttggtcg aggatagcca gggggggcga ctcctcaaaa
     9601 aggcgctaca ggaacggttg gaccatcagc tagaaatggt gttccgtctt ctggcgcttc
     9661 gatttcctgt gtcggacatc cgggacgcct atgcgggtct cactgtggat gacgcccgcc
     9721 ttcgggcaat agccacggag ttcatggaca accttcttcc atcccatctg aagcgatatc
     9781 tgattccgat catcgacaac tggccgtcgg acgccgtggt ggaagtcggc aggcaattcg
     9841 tctcgatcaa tgggtccaca cgggaagaac ttatcttgta cttgcttaag ggaacggatc
     9901 tctggttaaa gacatgtgcc atttacttag caggggaatg gaagctctca tctctgctca
     9961 gcgaactgcg gcaagccgct gatgactcag gacacttgat cagggagacg gttcacctgg
    10021 cgctcgaaca acttaacgac tagaccgaat gctcaccacg attgaaaaag tcctgctgtt
    10081 acaaggtgtc gatattttag tggatacgga aactgagaac ctggccaaga tcgcggccat
    10141 tgcccgggaa gtccgtttcg aagagggggc gacgattttt gaggagggcg agccaagcaa
    10201 tgcgttctac attgtgctgg agggaacggt ctcggtaagg aaaggttcga aggagatagg
    10261 actcgttaag gacaaggaga cggtcggatg ggtcaacttg cttgagcaga ccccgagaac
    10321 cgtgactctg gtggcgttaa ccggcaccac gttcctcaag atcgagcgag aaggcttgtt
    10381 tgacctgctc gctgatcatt tcgacattgt tcgcggcatc ctcaagcggc tgtcgcggat
    10441 tatcaatcaa cttttggaca gatgagatga gtccgattta tcttctgtcg tgtgccttaa
    10501 tcgtcatcgc gagctcgatg cttggttgtg aggtaagagt aagaaacctt ccacatacag
    10561 tggaataccg ttcggagctt gcatgtgaac caagctcgca agagtgcccc tgggctaatc
    10621 tggaacgaca agccaaattc accgcgcttg ttaattgcct cctgtcgggt gcgacgttct
    10681 ttcgcattga cgactctcag acgaccaatg gctcggagcc ttctctggta actcccattg
    10741 agccaagata tgggtatgaa cgtgcgacgg atcatggagc cgggcaggcc tgtccatccc
    10801 agaaaacggt ctgccaagtg gccagccggc atgagaggga actcacctgg gccacctgtg
    10861 gcacacagcc tttgaaagat gcgcccctgc gcggcggaaa taccttgacc catgcggata
    10921 gattgaccga aagcattgtg gtgaccggac gtttaagtga gggaaccgac gagttccact
    10981 ctccccatgg gttagacggt cccgatcact tctacacctt cgccttggct cagcggactc
    11041 gcatggagat agcggtggca gccaatactt cgcactggtc cgatgcggtg gggctcaccc
    11101 gggcagcctg gcaaccggca ttgtatctcc tctctgccga tggggcgatg ctcaaggagg
    11161 gacacgtctt ccgtgccggt gtcacctctt tgttccccgc ggaatttgag cctgggacgt
    11221 attatcttgt ggtggacagt tccataagag aatggtcgcg gggggacggg tactatcgcc
    11281 tctacgtcgg gttcaacgag gaagttatgg gcccactagt cccatgattt gctggcgtgc
    11341 gagactttgt tgccgcgttg gagagccaaa acagacggat caaggagact cgagtgctga
    11401 taaaggaact attgaggctt caagcaacgc aaacctattt gagagcgatc gtcggagggg
    11461 acttcaactt tgaacaccac tccccggagt atcaggagtt gctggttgca ggcctgagag
    11521 acacgcacat gatcgcaagc ccccgcactg acctgtacag ctccgacccg aatcagaaca
    11581 cgatcgtcca ccaggaagaa ctcaccatgc caccctccct tcgccaagcc atgacgaatc
    11641 ttccagaagc ggaacagcag aggatggccg aaggttatca ggacggtatg ggacaagcga
    11701 gacggatcga ttatctgttt cacatgggca agggcccaca cttacctaac gagtgtctgc
    11761 ggcagacgct gcttggagaa tctgcggctc tctctactcc gtccgggtcc gatcacttcg
    11821 gcgtgttgaa tacgtacatt cttgacccgt cgcagcgctg atcatttcta gctggagggc
    11881 tggggacagc gattctctgg ccgaggatcg cagagccgga ggctgctgtg gattcctgtg
    11941 tgaatggcag gcgagcggcc atcgatgaag gtctacaaga cgaaggacaa tgacagtgga
    12001 caccgctgag tcgtatcgtg agcggcaaaa cgaaaccgac tgatccctcc gccaagatgt
    12061 actacaacga ccgatggtca aagggtgcac gggccaatac caatggtgtg aagcaggccg
    12121 gtattggatg cttgctcttc gttggcggcg ccggtagctt agaagtgaaa cctggggttc
    12181 aatccgtcga tacgcctgag tttctgaagg actggaagca gggcgccctc gccacccggg
    12241 aagtcttgaa tctgctgcgc aaggaactca gcttggattg gtcctttctc tcaccttccg
    12301 ctgatttgtc ccctggccaa cgaacaggaa acttccggct tgggaaagat cagttgctgg
    12361 tggatgcgaa agggcagagc cgcatctcgg tcgaggatta tgccttagct atgattgacg
    12421 aggccgaggc gcctcatcat attcgccaac ggtttacggt gggttattga attgagatgt
    12481 ggaaattcct ctgcgcgcga gcacgttctg attcgcgcca caaccgactt gatagggaag
    12541 gagagacatt atgaacaacc atacgctgaa agggaaagta gctggcgccg gcgccaagaa
    12601 tctgggcggt ctcctcagcc gcgagttcgc caaaggtgga gccaaggtcg tggtgcacta
    12661 caacagcgat accacgaagc cgaacgccga cgacacggtg aaagccatca aagacatcgg
    12721 cggcgaggcc tacgccgtcc agggcgactt gaccaagccc accaatatcg ccgcattgtt
    12781 caaatccgcc aaggaccgct tcggcggcat cgatatcgct gtcaacaacg tcggcaaggt
    12841 gctgggcaag cccatcgtcg acaccaccga agcagagttc gactcgatgt tcgacatcaa
    12901 cgccaaagcc gcttatttct tcatcaagga agccggaaca aatctcaaca acaacgggaa
    12961 gatcatcacc atcgtgacct cactgctcgc ggccttcacc gacggctatt cgacctacgc
    13021 cggcggcaaa gcgccggtgg aacactttac ccgcgcagcg gccaaggagt tcggtccgcg
    13081 cggtatttcc gtgaccgcgg tcggtcccgg cccgatggac acgccgtttt tctacggcca
    13141 ggaaatgtct gaacgagtgg cttttcacaa gtcgcaggcc ttgaacggca atctcaccaa
    13201 gattgaggac attgtgccga tcgtaagatt ccttgctacc gagggttggt gggttacaga
    13261 tcaaacgata ttcgccaatg gtggatacac cactcgatga ttcgattggt gtcaaaaccc
    13321 taacagtcgg cttcagcagc gataagcgcg tcacactgcg ggcaagagtg atgagttgcg
    13381 ccaaatggtg aagcagcatt tgactgtgtg gcggaggaga agcaggacgg ccaggtcgta
    13441 ctctttgctc ggagaacgcg cacggtgaag ctgtgcacga tcgatgcgcg cagggaagct
    13501 taagcgggcc agccaagttc tattcagatt gtttcaagaa ggggcaaatt gaagtggtga
    13561 ggggtttaaa gcggttttcc gaatagggct attacatgag ccttcttctc gatcgcatac
    13621 ttgcagccga tttcgaggtt ccagatgtcg agttgctaag gtcacctaca gttgttcaga
    13681 caaacaatgt tgcccagtat cttcacggta ccaatcgtaa agatccagac gatcttaccc
    13741 aggactttcc taatattgca cctccttggc cgaatttctt cgtggaattc gccatgcctt
    13801 cgactatttg tgaggtaact ccggaaggat cgcaaatgat gcaatgggaa ggcccaaaaa
    13861 catttgggtt gcattggatg gcagggagac gaggttctta cgactttggt ttgcagcaat
    13921 cgctattcaa gacactttct gagtccacca atccctagat acgttcaaaa tatctagaag
    13981 ctgcagaaca agccgcttgg ttcgggcacg ttcatctctt cttggttgtt tcttacagtc
    14041 gagtaaaggg aaatcacttt gccacattgc cctccccgtt tactctggga cgttagacgg
    14101 gagaaatagt tgcgggccta agtccgaggc ggtagcgaac tcgggcaaca ggacaatgat
    14161 tttcatcatc tgaataaagc gggcacaatg aaaatgtggg tcaagtgttg tctcatgatc
    14221 atgctgtggt tcacggcttc gccatgtatt gccaatgccg cagtagtcag cgtggaagga
    14281 ctgcgtgtct catctggcat gcgatgttgg tacagcggcc tcccatgaca tccacgaccg
    14341 ttgaggtatt gtgcggtctg ctagactgcc actccttcgc ccgtcatgtc tctagaccgt
    14401 cgccttcaca gacgtgataa gatagactat cacgaactga aagtgggggc cacagtttga
    14461 gccacgcaat aggaacgacc aatgagtgaa aagctgatga cccagacgca gtggacccaa
    14521 ttgtgcgaca atgtggttct tgcctgtgcc tctcaacatt cacaacgcgc ctatcgtgcg
    14581 tcagcctcga tgtatcgggc gtgggtggca cggacgaagc tgatgctttt gtcgaaggcg
    14641 acggttctgc gctaccgtga ctatctgctg ctcaccaaga agctcgctcc gaaatcgatc
    14701 aatctccacc taactgtcct tcgccgtcta gcgcaggaag ggatggccga acaagtgctc
    14761 gatacctcga cagcaatggc aattctccgc attccgatgg ttcccaatcg tggggttcgt
    14821 gctggagtgt ggttgccgcg tgaacaggcg cagcgcatct tgagcgggcc gaacgtgctg
    14881 acgatcgtgg ggaaacgaga ctatctcgtg ttgatgctga tcctgcggtg tgggcttcgg
    14941 cgggcggaga ttgcgcagtt ggcggtgacg gtggtgcgtg aacacgaggg ccggtgggtg
    15001 ctggcgaatc tgcgaggcaa agggaaacgg cttcgcaccc ttcctctccc cggtgtggtg
    15061 aagaatgctt gggaccggtg ggtcgaggcg gctgggattg agtccggccg agtcattcga
    15121 gccatcaatc gccacggccg cgtctggggc aagggagtga cggaggatac gatctggagg
    15181 attgtcggac ggtacgcaca gctggccttg ggaaaacatg tggcgccgca tgacttgcgc
    15241 cgtacattcg gccggctgtg ttatgcactg accaaagata tgcgggagat tcagcagctc
    15301 tacggccaca gttctgtaat gacgaccgag aagtatctag gcgtagaacc tcatctcgtg
    15361 gattcggtga cagatcggtt gggcctgtcg tgatcgccat ctcgaaaaca gtataatcct
    15421 ggcaccgcca ccctccactg gaatcgcatc gatgcgcatg agaaagaggc ctgtcggtcg
    15481 acgcaactcg ccgaactttg cggaatcgga cgagtcgaac cgaggatcgc ttgggatctg
    15541 ccttcgggaa ttttcaattg gtgactctaa actcggtctc tttgaaaccc gcagccggtc
    15601 actgtggtgg ctactccaag cactttcacc tttctcaggc tagagatgtc agggtttccc
    15661 ctactgcgat ttcaccttac ttggctcatc aagaacggga agaagatctc ggtctaaggt
    15721 aaaatgtagt tgccgtatca aaacttataa caaggtagga cttcaatgtc acatcacgcg
    15781 cgccccaacg cagcatttgg gtacgtgggg tataggtgcc tggtatacta agcgttacct
    15841 cgccacacaa accaagagtt cagaagcttt tttgtcagac attctgacac gcgcgcccca
    15901 agagtgttgc taggatgggt acactcttgg tataccaggt actatggaat cagccagacc
    15961 attggtcaca tccgaccagg ccacagctct aatggcggca tttctacagg agcgagcgcc
    16021 gacgattgcc gataccaccg tcgcaaccta tgcccgaaag ctcagcacgt ttcacgaatg
    16081 gtggtgcaac catgaaccat cccttccctt ctccgaaacg ttggcgacac ggtacgcgcg
    16141 ctggctagca acgcacagca cacggagcca agcctcacaa ggcctgcatc tgtcggccgt
    16201 ccggcaatgg gcctgttttc tcctggccgc cggccacctg tctatcaatc cccttgcggg
    16261 tgtgtcaggg ccaccgcgag cgcggtggtt gcggcatcgc ctgctcaccc gtacggatct
    16321 ccaaggattg ttgaagcagt tcgcggtgac cacgctcgtg ggccaacggg actatctcct
    16381 cgctgcgttg atgattcgca cgggagcccg tgagtccgaa ctggccgtcg ccaatatcgg
    16441 tgatctcacg gagtacggag aggaaggaag tctgctgttg ttgcacagca aaggcaaagc
    16501 caaacaggaa cccgtcgtgg tacgaccgga tctcagcacg aagctctggg cttacctccg
    16561 ccagcgatat cctgacggcc gttttccgcc acacgacccg ctgctcacga atcatcatcc
    16621 gtcttcccga ggggaacgca tgacgacacg gggaatgcgc aagcagctaa aggccgcttt
    16681 tagggaagct ggccttgctg agccccatgt caccgccctg tcactccggc tgtcaggcgg
    16741 agccttggcc tatcggaaag gggcgagccc atctgagctc aagaagacca tgcggcatga
    16801 atccattcag accacccaag tcctcattga ccaggtcaac cgcatacgat ttggagcgga
    16861 acgctatctg gacgatattc agtagacaac aagatgggaa tgagagggta tctttcaagg
    16921 cgagggtcct gggttgcaat ggctggtcac accgcggccc ctgtatgtcc gcatggcgtg
    16981 gttggtgatg ataatgccgg tggcgagaga aatgtcgcca atttcttcgc tggtgtcagg
    17041 ccctggaagg ccatagagaa gcggtcgtgg ttgtactgat gctccccttc tgttcagggt
    17101 gtcgcgggcc ggtgcgccga atgggcggat agccgaggtt ccgggagatt cgggggatgt
    17161 cgcggccgct acgcagatgc gatgcacccg atccagcaag aaccgggtcc gcatcgcggc
    17221 aaagtgcagc ttgcggcgcg tgtgcgcgga tggcgtggca ccaaccccgc cggtccactg
    17281 actacccagc gtcggtgcca ggtcctcacc gtcttacgat tcaagctaaa ccgtcgggcg
    17341 gcgcccttga acccatattc gtcggcatag cgcaacatcg ccagccggct gttgatgaga
    17401 tgatgatgcc gtgtggcaat gtgcatgttt ctcagttcct tcgtcgtgat caatcgcatg
    17461 gaatccccac tggttaatcc ttgtgactgc attccatgcg gagggtcagc aagatatttc
    17521 agaatatgac gggtactacg cttcctccgc gctgtgtagt attttgcaca ttagcaacgc
    17581 cgaattgcgg acctacctgc gcgccgccct tctcaccgtg tcgcccctca aaacacatat
    17641 gccatccgat tcgttcgagc agcaggtggt tacggactat gaatggtctg aaggacgtcg
    17701 ggtttcgttg cgacggatac ggaccgtgct cgctttcctg cagcggcagt ttggagactc
    17761 gctccatggc tagtgtcaaa gtctatgcgt caaggcgtgg agtgatcgtg tgggatggcc
    17821 gagaccgatg gcaaccggac tctggtcact atgtgctgaa tttcgaggtg cagctgccgg
    17881 ccagaacggc ccggctccca tcgagaggcc gaaccagtcg gctagacaaa agatcggcgt
    17941 tggtctgatg gaatcgtggc gtggagcttg aaggacatgt gccagaacgg cctgtcagac
    18001 gtatcaagaa gccattccgc tggatctgtc attcgccgaa gcacgtgtga atctcggacg
    18061 gctgtgtcat gatgcggaaa aacaggcaga ggcggaggcg agccatcgcg cgccgattca
    18121 ctccgatcca gatggagccg tcgcatcttc aatttaggtg tggtacttga agaccaaggc
    18181 aaggaccagg cggcgatgca tgcctatgag taggcgctcg ggcatgacgg tgagtttgag
    18241 cgggcgcact gctgcctagc cggtctctac gagcgccacg gtcgcattaa agatgcgctc
    18301 cgtcataatg cggcagccag acggtgcggg aaaaaatcca cctcgagagt agcgttacag
    18361 aggtgggatt cgctcgttca tgagtacagc atcggttttg gtcacggccg aggtatggga
    18421 tgaagggggg aaagtgcatg tatcaggcag cgtcaggtaa ggtctgatcg ggacgcggca
    18481 gacggttctt ttgattcaag gtaaaggaag aaagcggtga acagctttcg atacatggga
    18541 atcagctcat tcgcgatgtc aattgattcc aggttgggtt gtgctgagag gcgcatcaca
    18601 cagtattgca caagcccttc tctatccctc gcgtcaatga agatggcgca gtcgtcacag
    18661 gcgagccatt caggactcat catggcaccc gtgccatgcg acggatgtaa atcctcagtg
    18721 gagacatggt cgagcccttg aatagtataa atcggcgtat cgccaaagac ctgacttgag
    18781 tcggtcagtc cgaatgggtg ggtccgatat ttggtggtgg ggattgaagc cgaacagaag
    18841 tcacaacaca acatcaggcc atcctcctac gtcttacccg atcaactagg catttcaagt
    18901 tatcgtctgg gtttacggag atgtgatgtg cacatgatcg gaaccccagc cgtacgcgcc
    18961 gctttctcca gcgcgtcgtc ggccgtggcc agttcagctt cagtccttat cgctgtatga
    19021 agataggccg catcatacgc ggaaaggccg tatcctcttc caagcggcag aagagcgtga
    19081 aaatgcgcgt ttatcgggac tgagacttcc tgtggtgaca acgcgtccaa gagatcgatg
    19141 aaccgtaaaa tgtcggattg gccgatgcgt cggcgtcgtt caccgacaag cagcccgttg
    19201 gtgatctcga gcgcccatac agacggcacg agaacagaac acccgtccag ctcctggagg
    19261 actttgtcgg cataaggact ttgctcatcc gggaagcacc atgccagcgc caccgaggca
    19321 tcgatcacca cgcgcctcaa cgccgacggc cctcctcgat catgtctttg acgggcatcg
    19381 cccctggctt cacccgcttg cgcaactcgc gcatgccctc gagaagagcc gcatgaggca
    19441 ggcgcccgac atctccctgt acgggaacca acttcgcagc aggcacgccg tgcctcgtga
    19501 tggtaatcgt ctctccctta ctcacccgtt caagcagggc agataaatgc gttttcgcct
    19561 caaatgctcc gatagtatcc atgtgcctgc ctccaattga tctagtctac aactagttga
    19621 agtttagcgt ctctcgtctg tcgagtcaag gcttccattg gaaatttagg ggatggtgcc
    19681 tggttgctcg atgtacgacc aagccaccct ccgcgagaag ccgtttaaac ctcgactccg
    19741 tttgggagtt ttcgcgccgt cgtcgagtat tcaggaacga ttccccgaac tcaacagtcg
    19801 gagaatcgct tcatcaacgc catcaacctc tgcgtcggag cagtgattgc gcttgcggta
    19861 gagcgcccgc agcccgggca ggaggacggc cggtgcttca tactccgcct ctcttccagg
    19921 tcgtgggacg cgcttgtcga ggatggtcgt ggtaggattt ggtgtccgag tctccacgcc
    19981 tggaatgtcg ggaacctagg gaacgcccgc ccacttggga taccttaaag tctattggac
    20041 tccagcgtgg atgaaatgtt tattcacggc agacgttatg tatttatgtg atcgcagtct
    20101 gtgagagccc aacgcgtgtc aaaaactcca tattgatccg caccgaagtt gagagtgtca
    20161 tggctagact ctttagtagc gtgtgatcgc atactccgcc ccttcctcca gccgatcaat
    20221 cgcgtgaaaa tacttttgag tggtgcggat gtccttgtga tccaacatag cttgaacttt
    20281 gaatggcgat tcagttcgag cggcctccgt cgcagccgta tggcggagac tatgtggcgt
    20341 cacccttcgt tgccgacgcc ggcgactttc caacgatgac gcctcgccag gtcgcgtgac
    20401 atcccgcagg ccgcagcggg tcatggctcc cgcaattcga agttggatgg cgcgggtcgt
    20461 tagtcgtaac cgctcatttg gcgccaacgt tgaagcctcc cctccgcccg gctttgaccg
    20521 tacctgcgcg agatgcgagg tgagcttatc atggtgcctg gcaaacaagg gctcgcgtgg
    20581 taacaccgga ccgcgtgcct ctagatatcg ttgaagccgg ccatagacct ctggcatcaa
    20641 attcacaaaa ctttctttcg tctgctgtcc ctttcc
//
LOCUS       DAOQPD010000067        20582 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1263_length_20582_cov_18.834072, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000067 DAOQPD010000000
VERSION     DAOQPD010000067.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 20582)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 20582)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20582
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1263_length_20582_cov_18.834072"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..960
                     /locus_tag="PK063_14075"
     CDS             <1..960
                     /locus_tag="PK063_14075"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HMZ98226.1"
                     /translation="YLDFEKPIRELEEKIEKLASAESPKSGTQDEIRKLRTKLAQVEH
                     QLYTTLTPWQRTQLARHPQRPTSLDYISELSREFLELHGDRSFGDDRAIVGGFARFND
                     RSVMIIGHQKGKTLKERMQRNFGMPNPEGYRKALRLMRLAEKFNRPIITLIDTPGAYP
                     GIGAEERGQAEAIARNLFVMSRLTVPIISVVIGEGGSGGALALGVSDRILMLEHSVYS
                     VISPEGCAAILYDDPTKVPDAAASLRMTAQDLVGLGIVDEVIPEPLGGAHRDPRAMCD
                     RVAKALANQLYALVELPTDQLIAERDQKFRKIGVVGGLVPVGA"
     gene            1259..2575
                     /locus_tag="PK063_14080"
     CDS             1259..2575
                     /locus_tag="PK063_14080"
                     /inference="COORDINATES: protein motif:HMM:NF019268.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HMZ98227.1"
                     /translation="MSKSIVNVCIVSLLCTWGAWTGDAWGQSRLTGLPTGDGSSPVFS
                     TQMPGKEGPGASDPLWTDALWQADQQGVQRFFPQDGFVRVRGWIDGGYTYNTSNPSSN
                     FNGPYNAIDRDIPVLNQLYMIIEKPLTATGSNWGIGGRLDFMYGYDFFLTQSNGAERR
                     ENGAQRWNAQGQHYGLAMPQAYAEIGNQTFSVKVGHFYTIIGYEGVPSINNFFYSKSF
                     AYQFAGPFTHWGGLATWHVNDRVTLQGGVVNGWDSLDRTKDSATGLASITYAAPENLW
                     SLSLSMVTGNEPGAVATQFETRTRYSAIFTLHPAERWEYVLHHHYAYQNQGKFDGGTA
                     RWYGIDNYLYYAFADQWRAGLRFEWMRDEAGTRVGGNPVRDNPNLGPFAGSFYSVSAG
                     LNYRPHPNVLIRPEIRADWFDGQRSPYNDGLNKNQVLAAINGNLQF"
     gene            complement(2609..3199)
                     /locus_tag="PK063_14085"
     CDS             complement(2609..3199)
                     /locus_tag="PK063_14085"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98228.1"
                     /translation="MTMIALPASCERALLERFLRAEAMALWAVRAAQTQQLPRHVQTF
                     LQRHETDEQDHLRQFEGMLGTMSQRPATLPTVPSQWEMLAVLLFGYEALGLEFASLLA
                     AIRPDLSDILEDEEVHVGFFEKELKAILAGGETGAQQAREAARTWWKKLPRTVDRYLG
                     DASLAPFRTELRQHILSVIRQRFVALSLLPAEQTNR"
     gene            complement(3202..3402)
                     /locus_tag="PK063_14090"
     CDS             complement(3202..3402)
                     /locus_tag="PK063_14090"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98229.1"
                     /translation="MQRLIWTSDKPKQTGWYWWRGLGEDMDPLILFVDQVGYFQWPDG
                     ASQEVGLTKGEWAGPIAPPEEQ"
     gene            3509..>4161
                     /locus_tag="PK063_14095"
     CDS             3509..>4161
                     /locus_tag="PK063_14095"
                     /inference="COORDINATES: protein motif:HMM:NF012492.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HMZ98230.1"
                     /translation="MDRLPIEEAIPPLRERLATGRSLLLTAQPGAGKTTRVPIALLDE
                     PWLSGQKLIMLEPRRLAARAAATYMAASLGEPVGRTVGYRIRHESKVSAATRIEVVTE
                     GILTRLLQQDPSLAGYGLVIFDEFHERSLQADLGLAFARESQRLFREDLRLLVMSATL
                     DCAAVTSLLSDATAISCEGRLFPVTTHYLDRPIDGHIEPAVVRSIKAALAKESGSLLV
                     "
     assembly_gap    4162..4261
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <4262..6162
                     /gene="hrpB"
                     /locus_tag="PK063_14100"
     CDS             <4262..6162
                     /gene="hrpB"
                     /locus_tag="PK063_14100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-dependent helicase HrpB"
                     /protein_id="HMZ98231.1"
                     /translation="VVRSIKAALAKESGSLLVFLPGMAEIRRVERQLHESRLDPDVII
                     APLHGELPQAEQEQAIDPAPSGSRKIVLATSIAETSLTIEGVRVVIDAGLMRVPRFDP
                     RTGLTRLDTIRVTLDAADQRRGRAGRLEPGTCYRLWTNAEHQALLPRRPPEMLEADLA
                     PLALELAEWGVLDAKELSWLDPPPAGALAQARDLLRQLGALDAQGALTAHGRRLAHVT
                     DHPRLAHMMVAAVPLGWGPWACDLAALLSERDILQGGPGWRNADLRLRIEALHGNKAH
                     LAGATINRTGCERVRRASEQWRRQLQLGIPSGDGIDHIGILLAFAYPDRVAQRLAGSD
                     GRYRLANGRGASFQGQQGLSQEDYLAVAQLDGTGDWARILAAAPLRLQDLERHCAKQI
                     DTVDVLEWDDRSESVRARRQRRFGQLILEDRATHEPDPGQVTAALLVGLRRTGLVALP
                     WTKDLHQWRARVAFLHRVDTTWPDLSDEALTTTLEQWLAPFVTGLMSLAQLRRIDLQA
                     PLDSLLTWQQRQELSRLAPTHITVPSGSHVRLDYEQGDSPVLAVRLQEMFGCQETPRI
                     AGGTVPVMVHLLSPAGRPVQVTKDLASFWRSAYQDVKKELRGRYPRHHWPDDPFSAQP
                     TNRTKRRT"
     gene            6271..6819
                     /locus_tag="PK063_14105"
     CDS             6271..6819
                     /locus_tag="PK063_14105"
                     /inference="COORDINATES: protein motif:HMM:NF025116.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HMZ98232.1"
                     /translation="MDHFAIVTAFGQDRPGIVALMADSLYQLGCNIEDSCMTRLRGEF
                     TMMLMVRLPQGIDAEALGRRLTVSTRPLDLAVLCRALPDQAALRQPMPEVPTFMLSVY
                     GADHPGIVAQVARTVADHGGNITDMNTRVIGSGEVPVYVMVLEIQLPEDRQSDQLKQA
                     LEALKPLLGVDLTFRPLDSVTF"
     gene            6822..7319
                     /gene="def"
                     /locus_tag="PK063_14110"
     CDS             6822..7319
                     /gene="def"
                     /locus_tag="PK063_14110"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HMZ98233.1"
                     /translation="MAIRPILHYPHPTLKSESAPTLPSDPATPVVVQDLLDTLAASPG
                     VALAAPQIGYALRVIVVDVSRKKGEKGHGLIVLINPVILVLEGPKILREGCLSVPDYT
                     GNVVRYEQAVVEGLAPDGRVVTLTTSGFEALAFQHEVDHLNGLLFLDRIQSLSTDLFR
                     RKTQS"
     gene            complement(7350..7799)
                     /locus_tag="PK063_14115"
     CDS             complement(7350..7799)
                     /locus_tag="PK063_14115"
                     /inference="COORDINATES: protein motif:HMM:NF019843.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ98234.1"
                     /translation="MMMDGRQWAPILATAAILMVAVVSPALADPASEHQLQALAGQGD
                     ANAQWMLGQALLTGNLGTTDEAEAVRWLQLAADQGHVLAQRDMGMLYEQGQGVTQDTL
                     EAFFWYSLASRQDSGRAKLRRDVLAAMLTPDQREAVAARLKGWRPSR"
     gene            complement(7814..9064)
                     /locus_tag="PK063_14120"
     CDS             complement(7814..9064)
                     /locus_tag="PK063_14120"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013739.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HMZ98235.1"
                     /translation="MSSSARVIIIGAGLAGLACAQHLVRRGLACTVLEASDEAGGRVR
                     TDRVDGFQFDRGFQVLLTGYPEAAKVLDYPSLQLQSFHPGALVRYGGRFHRISDPLRR
                     PQDLVAGLMSPIGSFRDKLTILRLRQDALNQRLCAQAGGGNRTTLEALDRYGFSAVMR
                     ERFLRPFLGGVFLDQSLSTPCRHFELVWAAFSRGAIALPQAGMGAIALQLASSLPAGS
                     IRLRAPVTQLDGKQVVLASGERLSADAVVLATDYATAATLRGEPVPAAPGRRSTTLYF
                     DAPTPPVPGPWLLLNGEQQGLIGTACVLSEVAPAYAPSGRALVSVSLADQTAPVDADQ
                     QQIVRAQLREWFGEAVDEWRHLRTDRISRALPPVDVLASRNGAASPRLRPALYQCGDY
                     CETGTLDGALLSGRHAAAAILADL"
     gene            complement(9074..9469)
                     /locus_tag="PK063_14125"
     CDS             complement(9074..9469)
                     /locus_tag="PK063_14125"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98236.1"
                     /translation="MMLKYVGVMLCSMLLWANAASAEWMKVGGTHKYDGYVDMATIGP
                     TGKTVTLWTLKDFKVDRQIPQGTYRSVRIKKQIDCEGHKSRPLHNKYYASQMGKGRPM
                     QSGKATREWSRVTPGSDGEAEFKIACKKV"
     gene            9572..10426
                     /locus_tag="PK063_14130"
     CDS             9572..10426
                     /locus_tag="PK063_14130"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: protein motif:HMM:TIGR00093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HMZ98237.1"
                     /translation="MQPSPQLLFHPPAVYCQAMTRKPSGTRRGEPAAIRPTPPADLDR
                     EKRVTLDRLLSKLGIASRSQAQEWIRAGRVRINQRLVRQPDTWVVWPGDAVTLDEQPL
                     QQGAPRFILFHKPKGVVTTHADEQGRRTIFDVLPPEFTRLHAVGRLDQATSGLLLLTN
                     DTALSSFLTDPKQRIRRRYLVTVRGEVTDDRAQAAIDGLEDQGERLHCAALTIQKRSG
                     RESHLDVTLTEGKNREIRRLFNALGHEVTRLRRIQYGPFALTDLEPGAWREIPIDAAK
                     ALLDKGLP"
     gene            10664..11113
                     /locus_tag="PK063_14135"
     CDS             10664..11113
                     /locus_tag="PK063_14135"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98238.1"
                     /translation="MKEIMKRFATGLTTLAFAAALLAPALTYANGADKAPLEIKVRVS
                     EKGFFDEKGKPYGGKRMLQVPKDTMVKITFVFGEDLTSLAAGDTHQITVRAEDGWKQE
                     TSPLWMMNRESTVSFLAGEKGRMQYRAYCILDCIGMEHLTNLFIQVV"
     gene            complement(11224..11640)
                     /locus_tag="PK063_14140"
     CDS             complement(11224..11640)
                     /locus_tag="PK063_14140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98239.1"
                     /translation="MTKYVSRSIIGISLGLLLWSGTGLATEPADVEKFVNARIEIGEM
                     MTNYFKGGESYGSGQRPSPEKMKEMGDDINGKLSDLLSKRGLSLEEYRVRSKEIFADK
                     EAVDAYLAKHPDLKARYDALPLSRMSGGGGSTGRGY"
     gene            complement(11744..12658)
                     /locus_tag="PK063_14145"
     CDS             complement(11744..12658)
                     /locus_tag="PK063_14145"
                     /inference="COORDINATES: protein motif:HMM:NF024109.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HMZ98240.1"
                     /translation="MLVSRILLVLALAGFVGCAGTTPPVRTNSGAHPPQLADVIPPDQ
                     PFQRHMVDLHGLHLSVLEAGTGDPIIFVHGVVTTSNIFPKYVGAYSPEFRGIAVDLRG
                     YGDSEKPATGYSIPQFSNDLIKLADVLQIKKAVWVGVSMGGMILQRLALDHPERVRAL
                     VLVSTTDGPMILDKDIPTIGAPRDYREVSKNMIVESFPADTQAKTYQPLLDRIPTWNG
                     TVIREALTSMSQFNVHGQLTRIQVPTLIMVGVKDDVATPAIAKGIQAQIAGSQVVEYQ
                     TGHFMMAEDPDRFRAVLGEFLKGLPPSQ"
     gene            complement(12773..13081)
                     /locus_tag="PK063_14150"
     CDS             complement(12773..13081)
                     /locus_tag="PK063_14150"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98241.1"
                     /translation="MKDVTISPSLVARSFKSDRAKPLSRGLSDLAGWLFTVNADRWRR
                     RAQFYERHRDYFPRVAASPFVDRCRELEAASREFAEVLFAMPPRVDLVPIQVTVSRIK
                     "
     gene            complement(13215..13967)
                     /locus_tag="PK063_14155"
     CDS             complement(13215..13967)
                     /locus_tag="PK063_14155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HMZ98242.1"
                     /translation="MAKITEVAPDLFRITTFLEPFNLQFSQFLVRDEQPLLFHTGPRA
                     LFADVKEAVASLIDVRTLRWISFSHFEADECGSLPDWQGVAPQSDAVCSLVGKLVSVD
                     DCLALRPAKGMADGEVLQTGKYRFQFLATPHVPHCWESGLLFEETQRTLLCSDLFHQA
                     GDGEPVTQSDVVGRCREVLMEYQQGPLANYMPYCTLTDPTLNRLAALKPNTLATMHGS
                     VYAGDGAQALRDLAHVFREILGSPAPVSMPSP"
     gene            complement(14067..14552)
                     /locus_tag="PK063_14160"
     CDS             complement(14067..14552)
                     /locus_tag="PK063_14160"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98243.1"
                     /translation="MAWLCYAAPLLFMIGPAAVMAHEPLTSILFHSAIGFSLSALIHR
                     IGHALLTPLPKGPHAIYLSATRRLPLRLTLSQFVWLLEGLVALGLFCGLLSKRCWLAG
                     GTEMLVAGWVLFLLGGGLFFLPVRLVKLWEMRHYPATSLVGPSDDVINRSLSCLPRLF
                     K"
     gene            14963..15142
                     /locus_tag="PK063_14165"
     CDS             14963..15142
                     /locus_tag="PK063_14165"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98244.1"
                     /translation="MKQQIQRPVRRTEQQKPTQDKDGVWPLSAREFMKLPVSGLLSTG
                     KRIRFTRLTPPDQAA"
     gene            15171..15359
                     /locus_tag="PK063_14170"
     CDS             15171..15359
                     /locus_tag="PK063_14170"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98245.1"
                     /translation="MLIEDSLLTHDERKAAEAAFRGLPLDAQWSRGAQTIYIGILEVT
                     RGRDIVGDDLWEEVAAAV"
     gene            complement(15433..15777)
                     /locus_tag="PK063_14175"
     CDS             complement(15433..15777)
                     /locus_tag="PK063_14175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HMZ98246.1"
                     /translation="MLNAEVMAEVLEFRRKRDWEQFHKPKELAAAITVEASELLEVFQ
                     WKTHEEVARLLGGPSRERVTDEIADVVILLSYLCHDLGLDVNEAVRAKLKKNEAKYPV
                     EKSYGNARKYDE"
     gene            15987..16535
                     /locus_tag="PK063_14180"
     CDS             15987..16535
                     /locus_tag="PK063_14180"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98247.1"
                     /translation="MNRRLLSALSLLLMLTAPVYAQSPCSDCFYAAEEEVRKCLDNAI
                     SAGDRNSCLDNRRVRLKACSDNQCQTVREETAITETQSTVSRPGVAPYTPTEAEWLAL
                     ITRAGLRREATPDRPYSLDIILADPQTLQIMVRHASTMDREQLRKAIEGARETIRNTA
                     KSYGWDKWVKIRESVEMYAAKK"
     gene            complement(16563..17069)
                     /locus_tag="PK063_14185"
     CDS             complement(16563..17069)
                     /locus_tag="PK063_14185"
                     /inference="COORDINATES: protein motif:HMM:NF017517.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine phosphatase family protein"
                     /protein_id="HMZ98248.1"
                     /translation="MLSNPSREQSHARTLTSYPLNLQGRIYGSAMPFGLYDPEGTLLP
                     KFRAAAIHGVVLLAEPDECREKTGRDLLAMYREEGLTVLPLPIPNYGIPVDGGLPEVL
                     KRVHEEAVQGHNVVIHCSAGLGRTALFATLLARSVLGLSGPDALAWLGRHQPGALLTP
                     AQIMLIME"
     gene            complement(17059..18144)
                     /locus_tag="PK063_14190"
     CDS             complement(17059..18144)
                     /locus_tag="PK063_14190"
                     /inference="COORDINATES: protein motif:HMM:NF021523.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2252 family protein"
                     /protein_id="HMZ98249.1"
                     /translation="MNILQATHEYERWSARQVPFVPADLRLKHRMMTQSAFSFLRATC
                     YRWLQVWPEVCADLTAAPALRAVADLHVENFGTWRDSEGRLIWGINDFDEACVFPYAS
                     DLVRLVVSAKLAGRAEHLAVKLDEACDAVLTGYLEGLRAGGRPFVLSEQHAWLRDIAT
                     NSLRDPVKFWKKMAALPMLKDTVPPEVANALEKVMPEAGLSYGLRRRVSGLGSLGRPR
                     VVALADWRGGKIAREAKRLIASAGLWARGQKPIGMLLYQLMLEQSVRCRDPFVGMDGS
                     WLLRRLSPYCSRIEVTALPKKRDEGKLLYAMGWETANVHLGDRAQIKAVQRDLAARKS
                     AWLKKAAKAMLKTTVADWKDWAEHHAE"
     gene            complement(18272..18967)
                     /locus_tag="PK063_14195"
     CDS             complement(18272..18967)
                     /locus_tag="PK063_14195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HMZ98250.1"
                     /translation="MMKTGRASFHVDHAAESRLGFPTVTVLPPKHFSMLREFHLADVL
                     TLGNAACGLAGVFFAMQYMSSHSLAHFLAAAALSPAALLFDWFDGRVARWRHQQSVLG
                     RELDSLADIISFGVAPAALAFAAGLRGGWDWIALTYFVCCGVSRLARYNVTAERLSAG
                     HDKVAYFEGTPIPTTALLTGVLAWAAWQDRLGEQLYGGVWTIGPGDLHALSLLFILSG
                     TLMISKTLHIPKL"
     gene            complement(19082..19399)
                     /locus_tag="PK063_14200"
     CDS             complement(19082..19399)
                     /locus_tag="PK063_14200"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98251.1"
                     /translation="MMKRTLQMCLVAALLTGGGGFAFAADPMKDKEASPTLGERITKD
                     AVKGTLMKMDGEFYQIRNTDGELVRVHVDKSTKLDKVVEGDMVKAYVTDKGHVTTLQR
                     IEK"
     gene            19499..19870
                     /locus_tag="PK063_14205"
     CDS             19499..19870
                     /locus_tag="PK063_14205"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98252.1"
                     /translation="MARSQAMDEWKGALPDSRHGGFQILDKESKEPILYHPIPGAKNT
                     GRMVREQNAGRDGLLKNRPRSICAGSYTQKKAPSSFEDGASKNLQFLYQAFITFPSCV
                     HNISIANSYDLTLSQPPQHGS"
     gene            complement(19921..20337)
                     /locus_tag="PK063_14210"
     CDS             complement(19921..20337)
                     /locus_tag="PK063_14210"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98253.1"
                     /translation="MGMHSLIRSLLCLSLSIGLVSMALAGDRLRIKNIVQHPADYDAK
                     VVTVEGRAKAVSTLPVHRGTRRCGGSAVYDSQLFALHDRSGTIGISTPGTCLPNVTKP
                     VVENEQLRVRGIVRVDRNNPKAVPVIDAETVDRVKR"
BASE COUNT         4289 a         6579 c         5865 g         3749 t
ORIGIN      
        1 tacctcgact ttgaaaaacc gatccgcgaa ctcgaagaaa aaatcgagaa gctggcttcc
       61 gccgagtcac ccaaatccgg aacccaggac gagatccgaa agctcagaac caaactcgca
      121 caggtcgagc atcagctcta caccaccctg acgccctggc aacggaccca attggcccgt
      181 cacccccagc gtcccacgtc cctcgactat atcagcgaac tctcccgcga atttctggaa
      241 ctccatggtg atcgcagctt cggcgacgat cgcgcgattg tgggcggatt cgcccgcttc
      301 aacgatcgct cggtcatgat catcggccat caaaagggga aaaccctcaa ggaacgcatg
      361 cagcgcaact tcggcatgcc caatccggaa ggctaccgca aagcgctgcg gctcatgcgc
      421 ctggcggaga agttcaaccg ccccattatc acgctgatcg atacaccggg cgcctacccc
      481 ggcatcggag cggaagagcg cggacaggcg gaagcgatcg ccagaaacct cttcgtcatg
      541 tcgcgactga ccgtgcccat tatttccgtt gtcatcggcg aaggcggcag cggcggcgcg
      601 ctcgcgctcg gcgtgagcga tcgtattttg atgctggaac attccgtcta ttccgtcatt
      661 tcccccgaag gctgcgcggc gattctgtat gacgatccga ccaaggtgcc cgacgccgca
      721 gcgtccctac gcatgaccgc gcaggacctc gtgggactcg gcatcgtgga tgaagtgatt
      781 ccagagccac tcggcggtgc ccaccgcgac ccgcgggcca tgtgcgatcg cgtcgccaag
      841 gcgctggcca atcagctgta cgcgctggtt gaattgccga ccgatcaact catcgccgaa
      901 cgcgaccaga agttccgcaa gatcggcgtc gttggcggac ttgtccccgt aggagcctag
      961 tcaccctcga attccccgcc ccgttcgttc ctacgcgatt ctgacaagcc gcaagaactc
     1021 gctcgcttcc ccgtcgctat ccgacgatta tttggtgtcg cctctcggca tcaccatact
     1081 cagcctgctc aggcgttcgt catgctccgc atccggatcc ggtatcaagc ctccctgaaa
     1141 ccacctacag ccttagcctg atttcccatc gcccggcgag ttggtacact gccgcccgcc
     1201 cgcgcagggt catcactgaa caggccatgg gagattttca caggaggtgt ggacaggtat
     1261 gtcgaagtcg atcgtgaacg tatgcatcgt gtcgttgtta tgcacctggg gcgcgtggac
     1321 cggagacgca tggggacagt cacggctcac cggcctcccg acgggcgatg ggtcttcccc
     1381 ggtcttctcc acgcagatgc ctggaaagga agggcccggc gcatcagacc cgctctggac
     1441 cgatgccttg tggcaagccg atcagcaggg agtccaacgg ttttttccgc aggacggatt
     1501 cgtccgcgta cgcggctgga tcgacggcgg gtatacgtac aataccagca accccagcag
     1561 caacttcaac ggaccctaca acgccattga ccgggacatt cccgtcttga accagttgta
     1621 catgatcatc gagaaaccgt tgacggccac ggggagcaat tggggcattg gcgggcgctt
     1681 ggatttcatg tacggctacg atttcttcct gacacagagc aacggcgcag agcgacggga
     1741 gaacggcgcg cagcgttgga acgcgcaggg ccagcattac ggactggcaa tgccccaggc
     1801 ctacgcagaa atcggcaacc agacgttttc agtgaaggtc ggccacttct acacgatcat
     1861 cggctatgaa ggggtgccgt ccatcaataa cttcttctac tccaagtctt tcgcgtatca
     1921 attcgcgggc cccttcaccc actggggcgg cttggccacc tggcatgtga acgaccgggt
     1981 gacgctgcaa ggcggcgtgg tgaacggctg ggattctctg gatcggacaa aggacagtgc
     2041 cacaggtctg gccagcatca catacgccgc gcccgagaat ttgtggtcac tttccttgtc
     2101 gatggtcacc ggaaacgaac ccggcgcggt cgccacacaa tttgaaaccc gcacccgcta
     2161 tagcgccatt ttcaccctgc acccggctga acggtgggaa tatgtgttgc atcatcacta
     2221 tgcgtatcag aaccagggca agttcgacgg aggcaccgca cgctggtacg gcatcgacaa
     2281 ttacctgtac tacgcctttg ccgatcagtg gcgagcgggc ctccgcttcg agtggatgcg
     2341 ggacgaggcc ggtacgcggg tcgggggaaa tccggtgcgt gacaacccga atctcgggcc
     2401 gtttgccggc tctttttatt cggtcagcgc cggactcaac taccgtccgc accccaatgt
     2461 gctgattcgc ccggagattc gagccgattg gttcgacggg cagcgctcgc catacaacga
     2521 cggcctgaac aaaaatcagg tattggcggc gatcaatggg aacctacagt tctagagtgg
     2581 gatggcatgg agcaggcagg ccggagtgtt accggtttgt ctgctccgca ggcagcaggc
     2641 tcaacgcgac gaagcgttgc cggatgaccg acaatatatg ttgccggagt tcggttcgaa
     2701 aaggcgccag cgacgcatcg ccgagatagc gatccaccgt gcgaggcaac ttcttccacc
     2761 aggtacgcgc ggcctctcgc gcttgctgtg cacccgtctc tccaccggcc agaatcgcct
     2821 tcaattcctt ctcgaagaat cccacgtgca cctcttcgtc ttccaggatg tcggaaagat
     2881 ccggcctgat cgcggccagc aacgaggcga attccagccc cagcgcttcg tacccgaaca
     2941 acagcactgc cagcatttcc cactgcgacg gcaccgtcgg caatgtggcc ggccgttgag
     3001 acatcgtccc gagcatgcct tcaaattgcc gaagatgatc ctgttcgtcc gtctcatgcc
     3061 gctggagaaa ggtctgcacg tggcggggaa gctgttgcgt ctgagcggcg cgcaccgccc
     3121 acaaggccat ggcttcggcc cgcaggaatc gttcgagcaa ggctcgttcg caggaggccg
     3181 gcagcgcgat catcgtcaca ctcactgctc ttccggcggc gcgatcggac cggcccattc
     3241 gcccttggtc aacccgactt cctgcgacgc cccatccggc cactgaaaat agcccacctg
     3301 gtcgacaaac agaatgagcg gatccatatc ctctcccagc ccacgccacc aataccaacc
     3361 cgtctgcttc ggtttgtcac tcgtccatat caatcgttgc atcgtccgtt acactcctga
     3421 tctcgcgcga cctctgattg gcactcggcg cgcagccccc gtttctgcta cagtcccgtt
     3481 gacgcgtcat tgcagcgcgc accctaccat ggaccgatta ccaatagaag aggcgattcc
     3541 cccgctccgc gaacggctgg ccaccggccg atcgttgctc ctgactgcac agccgggcgc
     3601 tggaaagacc acccgcgttc ccatcgccct gctcgacgaa ccctggctga gcggacagaa
     3661 gctgatcatg ctggaaccac gccggctggc cgcgcgcgcc gccgccacct acatggccgc
     3721 gagcctcggc gagccggttg gccgaaccgt gggctatcgc atacgacacg aatccaaagt
     3781 cagcgcggcc acccgcatcg aggttgtcac cgaaggcatc ctcacacgtc tcctgcaaca
     3841 ggacccgtca ctggccgggt acgggctcgt gatcttcgat gaatttcacg aacgcagcct
     3901 ccaggcggac ctcggtctgg ccttcgcgag ggaatcgcaa cggctgttcc gcgaagacct
     3961 gcgcctactc gtgatgtcgg ccaccctcga ctgtgccgcc gtcaccagcc tcctgtccga
     4021 tgcaacagcc atctcctgcg aaggccgact ctttcccgtg accacccact atctcgaccg
     4081 gcccatcgac ggtcacatag aaccggcggt ggtgcggagt atcaaggcgg ccctggcgaa
     4141 agagtcgggc agtctgctgg tnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4261 ncggtggtgc ggagtatcaa ggcggccctg gcgaaagagt cgggcagtct gctggtcttc
     4321 ctgccgggca tggcggaaat ccggcgcgtc gagcggcagc tgcacgagag ccggctggat
     4381 ccggatgtca tcattgcacc gttacacggg gaactgccgc aagccgagca ggagcaggcc
     4441 attgatcctg cgccgtcagg ctctcgcaaa attgtgctcg ccacctcgat tgcggaaacg
     4501 agtttgacga tcgaaggcgt gcgtgtcgtg atcgacgccg gactcatgcg tgtccctcgc
     4561 tttgatccgc gcaccggcct aaccaggcta gacaccattc gcgtcacgct ggatgcagca
     4621 gatcaacgtc gcgggcgcgc cggacggttg gagccaggta cctgttaccg tctttggacc
     4681 aacgccgagc atcaagctct gcttccccga cggccgccgg aaatgctcga ggcggatctg
     4741 gcacccctcg cattggagct ggctgaatgg ggcgtgctcg acgcaaagga actgtcctgg
     4801 ttggatcctc cgccggcggg agcactggcg caggccagag acttactcag acaactcggc
     4861 gcactcgacg cacaaggtgc cctgacggct catggccgcc gcttggccca cgtcacagac
     4921 catccacggc tggctcacat gatggtcgct gccgtaccgt tgggatgggg cccatgggcc
     4981 tgcgatcttg ctgcgctgct cagcgaacgc gacatcctgc agggcggccc cggttggcgc
     5041 aacgccgact tgcggttgcg catagaagcg ctacacggca acaaggcaca tctggccggt
     5101 gcgacgatca accggacagg ctgtgaacgg gttcgtcgag cctcggaaca gtggcggcgc
     5161 caacttcaac tgggcatccc atcgggtgac ggcatcgatc acatcggcat cctgctggcc
     5221 tttgcctacc cggatcgcgt ggcgcaacgg ctcgccggca gcgacggacg gtaccgcctc
     5281 gccaatggac gcggcgcgtc gttccaaggc cagcagggtc tctcgcagga agactacctc
     5341 gccgtggcgc agctcgacgg caccggcgac tgggcacgca tccttgccgc cgcgccgtta
     5401 cgtctccagg acctcgaacg ccactgcgca aagcagatcg acactgttga tgtgctggaa
     5461 tgggatgatc gatcggaatc ggttcgtgcg cgacgccaac ggcgcttcgg ccaattgatt
     5521 ctggaggacc gcgccaccca tgagcctgat cctgggcagg tcactgccgc actgctcgtc
     5581 gggctccgtc gtaccggact cgttgccctg ccctggacga aggacctaca ccagtggcgg
     5641 gcacgcgtcg cgtttctcca tcgcgtcgat accacctggc ccgacctgtc cgacgaagct
     5701 ctcaccacaa cccttgagca atggctcgcc ccctttgtga cgggactcat gagcctggcg
     5761 caactccgtc gcatagacct gcaagccccc ctcgacagcc tgctgacctg gcagcaacgc
     5821 caggaattgt cccgcctcgc gccgacgcac atcaccgtgc cgagtggctc gcatgtccgg
     5881 ctcgattacg agcagggcga ctcgcctgtg ctggcggtac gcttgcagga aatgttcgga
     5941 tgccaggaga cacccagaat cgcgggagga acggtgcccg tcatggtcca cctgctctca
     6001 ccggccggca ggcccgtgca agtcaccaaa gacctggcaa gtttctggcg atcggcgtac
     6061 caggatgtga agaaggaatt gcgcggccgg tacccacgcc accattggcc tgacgatccg
     6121 ttcagcgccc agccgaccaa caggaccaag cgacgcacgt aaccattcag cgatgaccga
     6181 ttcgaagaac accgcctcta cttgccaatc gtcaccgaat cccgcatgct acgcggcacg
     6241 tctgacggac gatcacccta cgagttttcc atggaccact tcgccatcgt caccgccttc
     6301 ggtcaggacc gccccggcat cgtcgccctc atggccgata gcctttacca actcggctgc
     6361 aacatcgaag acagctgcat gaccagactc aggggcgagt tcacgatgat gctcatggtc
     6421 cgcctgccgc aaggcattga cgccgaagcc ttgggccgta gactcaccgt gtctacacga
     6481 ccgctggacc ttgccgtgct ctgcagagcg cttccggatc aggcggcgct ccgccagccc
     6541 atgccggagg ttccaacctt catgttgtcg gtgtacggcg cggaccatcc cggtattgtg
     6601 gcgcaggttg cacgcaccgt ggcggaccac ggcggcaaca tcaccgacat gaacacccgc
     6661 gtcatcggtt cgggcgaggt gcccgtctac gtcatggtgc ttgaaatcca actgccggag
     6721 gaccggcagt cggatcaact gaaacaggca ctggaagcgc tcaagccatt gctaggtgtc
     6781 gatctgacgt tccgcccgct cgacagcgtg acgttctaat cgtggcgatc cgtccgatcc
     6841 tgcactatcc ccatcccaca ctgaaatccg agagcgctcc cactctgcct tccgatccgg
     6901 caaccccggt cgttgtgcaa gacctgctcg ataccctggc cgcatctccc ggagtggccc
     6961 ttgccgcgcc gcagatcggc tatgccctgc gtgtgatcgt cgtagatgtg tcgcgcaaga
     7021 agggcgagaa gggccatggg ctgatcgtgt tgatcaaccc ggtgattctc gtgctggaag
     7081 ggccaaagat tctgcgggag ggctgcttga gcgtgccgga ctacaccggc aacgtggtac
     7141 gctatgaaca ggcggtggtg gaaggcctgg cgccggacgg cagggttgtc acactgacca
     7201 cgtcaggatt cgaggcgctg gcgtttcagc atgaagtaga ccatctgaac ggtctgctgt
     7261 ttctggaccg cattcagtcg ctcagcacgg acctcttccg ccggaaaacg cagagctgag
     7321 aagcatcaag ccctgctcgt gcgagaagat catcggctgg gccgccaccc cttgaggcga
     7381 gcggccaccg cttcgcgctg gtctggtgtc agcatggctg ccaggacatc acgccgcaat
     7441 ttggcccgcc cactgtcctg acggctggcg agggaatacc agaaaaaggc ttccagcgta
     7501 tcctgggtca cgccctgccc ctgctcgtac aacatgccca tgtcgcgttg cgccaacaca
     7561 tggccctgat ctgcggccaa ttgcagccaa cgcacggcct cggcttcatc ggtcgtgccc
     7621 aggtttcccg tgagcaaggc ttggcccaac atccattgcg cattcgcatc gccctgcccg
     7681 gcgagcgctt gtagttggtg ttccgaggcg ggatcggcca gtgcaggcga caccacggcg
     7741 accataagga ttgccgccgt cgccagtata ggtgcccact gtctcccgtc catcatcatc
     7801 accccatcgt cgctcacaga tcggccagga tcgcggcggc ggcatggcgc ccggacaaca
     7861 gcgccccgtc cagcgtaccg gtttcgcagt agtcgccgca ttgatacaaa gcgggccgca
     7921 ggcgcggaga cgcggcgcca ttccgactcg caagcacatc gaccggaggc aacgcccggc
     7981 tgatgcgatc ggttcgcagg tgccgccatt cgtctactgc ctcgccaaac cattcacgca
     8041 actgtgctcg tacgatctgc tgctggtctg cgtcgacagg cgccgtctga tcagcaaggc
     8101 tcaccgaaac gagcgcccgt ccagaagggg cataggccgg cgcgacctcg ctcaacacac
     8161 aggccgtgcc gatgagccct tgctgttctc cgttcaacaa caaccaaggc ccaggcacag
     8221 gcggagtggg tgcgtcgaaa tagagcgtcg tcgaccgacg gccgggtgcg gctggtaccg
     8281 gctctcctcg caacgtggcc gccgtggcat aatcagtcgc cagcacaacg gcatcggccg
     8341 agagacgttc gcccgaggcg agcacgacct gcttgccgtc gagttgcgtg acaggcgcac
     8401 gtaggcggat cgaaccggct ggaagtgagg aggccaactg aagcgcgatc gcgcccatgc
     8461 cggcctgcgg caacgcaatc gcgccgcgcg aaaatgccgc ccacacgagt tcaaagtgcc
     8521 ggcagggcgt ggagagggat tgatccagaa acacgccccc gaggaacggc cggagaaacc
     8581 gctcgcgcat gaccgcggaa aatccatagc ggtccaaggc ctctaaggtc gtacgatttc
     8641 cgccgcctgc ttgcgcgcag aggcgctggt tcagcgcgtc ctggcggagg cggagaatcg
     8701 tgagcttgtc acggaacgag ccgatcggac tcatcaaccc ggccaccaga tcctgagggc
     8761 gacggagtgg atcactgatg cgatgaaagc ggccgccgta acgtaccagc gcgccgggat
     8821 gaaaggattg cagctgcaga cttggatagt cgagcacctt cgcggcctcg ggatagccgg
     8881 tgagcaacac ctgaaagcct cgatcgaatt gaaagccatc cacccgatcg gtgcgaaccc
     8941 ggccccccgc ctcatccgat gcttcgagaa cagtgcaggc cagccctcgt ctgaccaggt
     9001 gttgtgcgca agccagcccg gcaagaccgg caccgatgat gatgacacga gcgctggaag
     9061 acatgaggcg ccgctacacc tttttacagg cgatcttgaa ctccgcctcg ccgtcactcc
     9121 ctggcgtgac ccgcgaccat tcgcgtgtgg cctttcccga ttgcatggga cggcccttcc
     9181 ccatctggct cgcataatat ttgttgtgta acgggcgact cttgtggccc tcgcaatcga
     9241 tttgtttttt gatccgcacc gatcgatagg tgccctgcgg aatttgtcga tccaccttga
     9301 agtccttcaa cgtccagagt gtgaccgttt tgcccgtcgg gccgatcgtc gccatgtcta
     9361 catacccatc gtacttatgc gtgccgccga ccttcatcca ctcagccgac gccgcattcg
     9421 cccacagcaa catcgagcag agcatcaccc ccacatattt cagcatcaca cctgactccc
     9481 cctcgacata tcattcagtc ctgacgatca tgcgccgcaa ccgcacaggt acggcaaaac
     9541 cgccgtcatc ataccatcgg aggccgatga catgcagccg tcgccgcagc ttctctttca
     9601 ccctcccgca gtgtattgtc aggccatgac cagaaaaccg tcgggcaccc gaagaggcga
     9661 gcccgcagca attcgcccaa cccctcctgc cgatctcgac cgcgagaaac gcgtgacgct
     9721 ggaccgtctc ctctcaaaac tcggcatcgc cagtcggagc caggcacagg aatggatcag
     9781 ggccggacgg gtccgcatca atcagcgcct cgtacggcag ccggacactt gggtagtctg
     9841 gcccggtgat gccgtcacgc tcgacgaaca gccgcttcaa caaggcgccc cgcgattcat
     9901 cctgtttcac aaacccaaag gagtggtcac cacgcacgct gacgaacaag gccggaggac
     9961 catttttgat gtactgccgc cggagttcac ccgcctgcat gccgtcggac ggctggacca
    10021 agccaccagc ggcctcctcc tcctcaccaa tgacacggca ctctccagct tcctcaccga
    10081 cccgaaacag cggatacgac ggcgttacct ggtcaccgtg cgcggcgagg tcacggacga
    10141 ccgcgcgcag gcggccatcg atggactcga ggatcagggc gaacggcttc actgcgcggc
    10201 gctgacgatt caaaagagat ccgggcgtga atcgcatctg gacgtgacgc tgaccgaagg
    10261 gaagaaccgg gaaattcgac gcctgttcaa cgcgctgggt cacgaagtca cgaggctgcg
    10321 ccgcattcaa tacggcccct ttgcgctcac tgatcttgaa ccgggcgcct ggcgcgagat
    10381 cccgatcgat gccgccaaag ccttgctgga caagggttta ccctgagtcg acacctatct
    10441 tcttttccta cgtgctgcgc ctgctcatcc ggtgaaagaa cttgccaacc accggtgctg
    10501 tgctaaggtc aatacagcag gcgaagcgtt cgggaacaca cagtccgcat cgtactgaac
    10561 aacccactcc gctctcgtct ccgcaacatt acaccaccgt cgctcccgac cagggaaggg
    10621 ccggctccaa cagcagccgg ccggaatata ggagatcagg atcatgaagg agatcatgaa
    10681 gcgattcgcc accggcctca ccaccttggc ctttgccgcc gccttgctgg cgccggcgct
    10741 gacctatgcc aacggcgccg acaaggctcc gctggagatc aaggtgcgcg tgagcgaaaa
    10801 gggattcttc gatgagaaag gcaaacccta tggcggaaag cggatgctgc aggtgcccaa
    10861 ggacacgatg gtgaaaatca ccttcgtctt cggtgaagac ctcaccagtt tggccgcggg
    10921 agacacgcac cagattaccg ttcgcgctga agacggctgg aagcaggaaa ccagccctct
    10981 gtggatgatg aatcgggaat cgacggtcag tttcctggca ggcgagaagg gccgtatgca
    11041 gtaccgcgcc tactgcatcc tcgactgcat cggcatggag cacttgacga atctgttcat
    11101 ccaggtcgta taaggcggct tcccgggcca gcgcggctca cgaaatgaaa acgctcggcg
    11161 tactgatgca tacgccgagc gtttcaattt ttgagcaggt cttgagcgag agcgacccgc
    11221 ctgctaatac ccccgaccgg tgcttccccc acccccgctc atccggctga gcggcaacgc
    11281 gtcataacgc gccttcagat cgggatgttt ggccaggtag gcgtcgaccg cttccttatc
    11341 ggcgaagatt tctttgctgc gcacgcgata ttcttccagc gacaggcctc gcttcgacag
    11401 caagtcactg agcttgccgt tgatatcgtc gcccatttct ttcattttct ccggcgacgg
    11461 ccgctgccct gatccgtacg attccccgcc tttgaaatag ttcgtcatca tttcgccgat
    11521 ttcgatgcgg gcattcacaa acttctccac atcagccggt tccgtcgcca ggccggttcc
    11581 cgaccacagc agcagaccga gtgagatgcc gatgatcgat cgcgatacgt acttggtcat
    11641 aatctcccct ctgagtgata gagccatgtg aactgtcttc cggcatcata ccatcccgcc
    11701 ggatgcggcg cacgggccgc gaatcgcccg cgtgcctgcc gcactactgc gatggcggca
    11761 accctttcaa gaactccccg agcacggcgc gaaaccgatc ggggtcttcc gccatcatga
    11821 aatggccggt ctggtactcc acgacctgcg aaccggcgat ctgcgcctgg atgcccttgg
    11881 caatcgccgg tgtcgccaca tcatctttga cgccgaccat gatcaatgtc ggcacctgga
    11941 tacgcgtcaa ctggccatga acgttgaact gcgacatgga ggtcagtgcc tcccggatca
    12001 ccgtgccgtt ccaggtcgga atacggtcga gcagcggctg ataggtcttc gcctgcgtgt
    12061 cggccgggaa actctccaca atcatgtttt tcgacacctc gcgatagtca cgcggcgcgc
    12121 cgatggtggg aatgtccttg tccagaatca tcggcccgtc ggtcgtggaa accaagacca
    12181 acgcccgcac acgctcagga tgatccaacg ccagccgttg cagaatcatg ccgcccatcg
    12241 acacacccac ccacaccgcc ttcttgatct ggagtacgtc ggccagtttg atcaggtcgt
    12301 tggaaaactg aggaatggaa taaccggtcg ccggcttttc cgaatcgccg tagccgcgca
    12361 aatctaccgc gatgccgcga aactccggcg aataggcccc gacatatttg gggaagatat
    12421 tgctggtggt gaccacgccg tggacgaaga tgatcggatc gcccgtcccg gcttccaaca
    12481 cgctgagatg aaggccgtga agatcgacca tatggcgttg aaacggctga tcaggcggaa
    12541 tcacgtccgc gagttggggc ggatgtgcgc cgctgttcgt gcggactgga ggggtcgtgc
    12601 cggcgcagcc gacaaacccg gccagggcca gtacgagaag gattctagaa accagcatat
    12661 ggctcccctt tctgaatagg ctgacagcta atggcttagc gtaagctgtc agccgcacag
    12721 attcaatgct ggaatcccat gagaggaggg atgtggttcg aatccccgtc cattacttga
    12781 tccgggagac cgtcacctgg atcggcacca agtcgacccg tggcggcatc gcgaacaaca
    12841 cctcggcgaa ttcgcgagag gccgcctcca gctcccgaca acgatccacg aacggactcg
    12901 cggccacgcg cgggaaatag tcgcgatggc gttcgtaaaa ctgtgcccgc cgccgccagc
    12961 gatcggcatt gacggtaaat aaccagccgg ccaggtccga gagtccccgc gacaacggct
    13021 tcgcccgatc cgacttgaaa ctgcgtgcaa ccaacgatgg agatatggtc acgtctttca
    13081 tggctgcgcc tccctcccat gcgcccgatt cgacgcccgt catcatggcg gccgggtggc
    13141 gtctctgccg gctcaccttg cctcactgta ggccggcgac atgaggaatg gattagttca
    13201 gcatgaaaaa gatttcatgg agatggcatt gagacggggg ccgggctacc gaggatctcg
    13261 cggaagacgt gagccaggtc gcgcagcgct tgcgccccgt cgcccgcata gaccgaacca
    13321 tgcatggtcg ccagagtgtt tggcttcaac gccgccaacc ggttcaaggt gggatccgtc
    13381 aacgtgcagt agggcatgta gttggccagc ggaccttgtt gatattccat gagtacctcg
    13441 cgacagcgcc cgacgacatc ggactgggtc accggttcgc catcgcccgc ctgatgaaac
    13501 aggtcggaac agagcagcgt gcgctgcgtc tcttcgaaca acaggcccga ctcccagcaa
    13561 tgcggcacat gcggcgtcgc cagaaactga aaacggtact tgcccgtctg cagcacctct
    13621 ccatccgcca ttcccttcgc cggacgaagc gccaggcaat catccacgct caccagtttt
    13681 ccaaccaggc tacacacggc gtctgactgc ggggcgaccc cctgccaatc cggcagcgac
    13741 ccacattcgt cggcttcgaa atggctgaag ctgatccagc ggagcgttcg cacgtcgatc
    13801 agggaagcca ccgcctcttt cacatcggca aacagtgcgc gcgggccggt gtgaaacaac
    13861 aacggctgct cgtcacgcac caggaattgg ctgaattgaa ggttaaacgg ttcaaggaag
    13921 gtcgtgatac gaaacaggtc cggagcgact tcagtaatct tcgccatgat gccctccagc
    13981 atgaatgtgg ctggcatcgt aacgggtgga cgggacagga tcaagatgcg cagaacgcgc
    14041 ctaggctctg tgagaagacg gacagattac ttgaacaggc ggggcagaca ggaaagcgac
    14101 cgattgatca cgtcgtcgga cggaccgacc agcgaggtgg cgggatagtg ccgcatctcc
    14161 cagagcttga cgagtcgcac cggcaggaaa aacaatccgc cccctagcag aaacaggacc
    14221 catccagcca caagcatctc cgtaccaccg gcgagccagc aacgcttcga cagcaggcca
    14281 cagaatagcc ccaaggcgac caggccttcg agcagccaga cgaactggct cagagtcaat
    14341 cgcagaggaa gccgccgggt cgcgctgaga tagatggcat ggggcccctt aggcaacggc
    14401 gtcagtaatg cgtgaccgat gcggtggatc agtgcgctca aggaaaagcc gatggcgcta
    14461 tgaaagagaa tacttgtcag cggctcgtga gccataactg ccgcggggcc gatcatgaat
    14521 aacaggggcg cagcgtagca gagccacgcc atcacgtcct cgtaggtgaa cgttcgcaac
    14581 agatcgcggc aaccttgcgt aaacgcatct ggcctgggag cgcgattata ttccataaca
    14641 gtggtaggcg gagcgtgacc gatagaacgg agaggtgtaa atcggtgagt tcctggcctt
    14701 atctcgagca gaatgatgga tgtatacgaa cttgctgttc aggtcgtttg tatcgtggtg
    14761 ataccgaaac gtcaaacaaa gaaatgtttt tcgtcgaaat gaaacctggc accggcacat
    14821 ggtttcgatc caaaaggccg cctgaccgac tagggagaag ccttcccggc cccagggatt
    14881 ccgctagtcg tgacttccga cgacaggcgg tagaacaaca tacaggcagg ttgatcgctc
    14941 ttcatcacgg gaggaggaca ccatgaaaca gcagatccag cgcccggttc gacgcaccga
    15001 acaacagaag cccacccaag ataaagatgg tgtctggccc ctgtcggcac gcgagttcat
    15061 gaagcttccc gtgtcgggac tgctctcgac cgggaaacgc atccggttca cgcgcctgac
    15121 gcctcccgat caagcggcct aaggcgcggg aaaggattga gaggtgcacc atgctcatcg
    15181 aagacagtct cctcacacat gacgaacgca aggccgccga ggccgccttc cgcggccttc
    15241 ccctggacgc acaatggtcc agaggggcgc agaccattta catcggcatt ctcgaagtga
    15301 ctcgggggcg cgatatcgtg ggagatgacc tgtgggaaga ggtggccgcc gccgtctgat
    15361 tccagggcga tcccgcgccg ccgagccgca ggccccgctg accatcacgc gcggggcctg
    15421 cagagcctat cgtcattcgt catatttccg agcattgccg tacgactttt ctaccggata
    15481 cttcgcttcg ttctttttca gtttcgcacg cacggcctca ttcacgtcga gaccgaggtc
    15541 gtgacagaga taggaaagca gaatcaccac atcggcaatt tcgtccgtga cgcgttcacg
    15601 ggacgggccc ccgagcagcc gcgccacttc ctcgtgtgtt ttccattgaa agacttccag
    15661 cagttcactc gcctcaaccg taatggcggc agcgagttcc ttgggcttat gaaactgctc
    15721 ccagtcacgc ttccgccgaa attccaatac ctccgccatc acctcagcgt tcaacatcac
    15781 tgacgctcct tatatgcgta acgaaaccaa tcccgtatcc ttgtctaccc gctgtcggta
    15841 cgcgccgctc ttgcgggcag tgtgcgacct tgccctgatt gtttgcaagc gccggcctgc
    15901 tgcccgacag ccgtgacaca caatccgacc gaatgattga aatcgcgcgg cgagtggcgt
    15961 agagaattgg cacgggaggt cccatcatga accgacggct gttgtccgcc ttgtctctcc
    16021 tgctgatgct cactgcgccg gtctatgccc aaagcccctg ctccgattgc ttctacgctg
    16081 ccgaagaaga ggtgcgcaaa tgcctggaca atgccatcag cgcgggcgat cggaatagct
    16141 gcctggacaa ccggcgggtg cgcctcaagg cctgtagcga caatcaatgc cagaccgtca
    16201 gggaggaaac ggcgatcacg gagacgcaat cgacagtcag ccggcctggc gtcgcgccct
    16261 acacgccgac ggaagccgaa tggctggcct tgatcacgag ggccggcctc cgacgggaag
    16321 ccacaccgga ccgcccctac tcgctcgaca ttattctcgc cgatccacag actctgcaga
    16381 ttatggttcg acatgcgtcc acaatggatc gggaacaact gcggaaagcc atcgaaggcg
    16441 caagggagac gatccggaac acggccaaaa gttatggctg ggacaagtgg gtcaaaatac
    16501 gagagtcggt ggaaatgtat gcggcaaaaa aatgaatccg gtgcggctac gcgtctgacg
    16561 ggtcactcca taatcagcat gatttgcgcg ggcgtgagca gcgcgcctgg ttgatggcgc
    16621 cccagccagg ccagggcgtc cggtccggac agtcccaaca ccgatcgggc gagcaacgtg
    16681 gcaaacaggg ccgtgcggcc gagtccggcg gaacaatgaa tcactacgtt atggccctgg
    16741 acggcctctt catggacccg cttcagcacc tcaggcaggc cgccatcgac gggaatgcca
    16801 tagttgggga tcggcagcgg caacaccgtc aggccttctt cccgatacat cgccaataga
    16861 tcccgtcccg tcttttcccg gcattcgtcc ggctcagcga gcagcaccac gccatgaatg
    16921 gccgccgctc tgaacttcgg cagcaacgtc ccttccggat catagaggcc gaatggcatg
    16981 gcgctgccgt agatgcgacc ctggagattg agcgggtatg acgtcagcgt cctcgcgtgg
    17041 ctctgctctc gtgatggatt actcagcatg gtgttccgcc cagtccttcc agtccgcgac
    17101 cgtcgtcttt agcatcgcct tggccgcttt cttcagccag gcagattttc gcgctgccag
    17161 gtcgcgctga acagccttga tctgcgcccg gtcgccgaga tgtacgttcg ccgtctccca
    17221 gcccatcgca tacagcagct tgccctcgtc ccgctttttc ggtaacgccg tcacttcaat
    17281 ccgggagcaa tagggcgaca gccgccggag caaccaggag ccgtccatcc ccacgaacgg
    17341 atcgcggcaa cgcacggact gctccagcat caattggtac agcaacatgc cgattggctt
    17401 ctgccctcgc gcccacagac cggcggacgc aatgagccgc ttggcttcgc gagcgatttt
    17461 tcccccgcgc cagtcggcca gcgccaccac acgcggacgc cccaggctgc cgagccccga
    17521 tacccgccgt cgcagaccat acgagaggcc tgcttccggc atgaccttct cgagagcgtt
    17581 cgccacctcc ggggggactg tgtctttgag catcggcaga gccgccatct ttttccagaa
    17641 cttcaccgga tcgcgcaggg aattcgtggc aatgtcccgc aaccaggcgt gctgctccga
    17701 caacacaaag ggccgtccgc cggcgcgcag gccttcgaga tagcccgtca acaccgcatc
    17761 gcaggcctca tccaacttca cggcgagatg ttcagcccga ccggcgagtt tggcgctgac
    17821 gaccaaccgc accaggtcgc tcgcataggg aaagacgcag gcttcgtcaa aatcgttgat
    17881 gccccagatc aagcggcctt cgctgtcccg ccacgtgccg aaattttcga catggagatc
    17941 ggcgactgcc cgcagcgccg gagccgcggt gagatcggca cagacttccg gccacacctg
    18001 cagccaccgg taacaggtcg cccgcagaaa cgaaaaggcg ctctgcgtca tcatccggtg
    18061 cttcagacgc agatcggccg gcacaaacgg cacctgccgc gctgaccatc gctcatactc
    18121 atgcgtcgcc tgaagaatgt tcatgggtgc tgcctgctca gtggcgctaa ggtctcacgt
    18181 cttcagtccg atcgcaagac gggaatcgct cgtaggagga cagcaggata ggaaggacgt
    18241 cactggacct gatgggatca cacagcgggt cttagagttt ggggatgtga agggtcttgc
    18301 tgatcatgag cgtaccggaa aggatgaaca gcagagacaa ggcatgcagg tcgccaggcc
    18361 cgatcgtcca cacacctccg tagagctgct cgccgagccg atcctgccac gctgcccagg
    18421 ccagcactcc ggtcaggagc gccgtggtcg ggatgggcgt gccttcgaaa taggccacct
    18481 tgtcatggcc ggcagaaagg cgttcggcgg tcacgttata gcgggccagc cggctcacgc
    18541 cacagcagac aaaatacgtc agtgcgatcc agtcccaccc tccccgcaga cctgcggcaa
    18601 aggcgagcgc ggcgggtgcc acgccgaacg agatgatgtc ggccaaggaa tccaattccc
    18661 gtccaagcac cgactgctga tgccgccacc gggcgacacg accgtcgaac caatcgaaca
    18721 gcagcgcggc cggcgacaac gccgcagcag ccaaaaagtg agccagcgaa tggctgctca
    18781 tgtactgcat cgcaaagaac acacccgcga gcccacaagc ggcattgccg agtgtgagca
    18841 catcggcgag atgaaactca cggagcatcg aaaaatgttt gggtggcaac acagtcacgg
    18901 taggaaaacc caagcgggat tccgctgcat ggtccacgtg gaaacttgcc cggccggttt
    18961 tcatcatcgg ccactcgaca ggaaaaataa tagcagatta ctcacgattg agaaacggca
    19021 tgcacagcgc ccatgggcgg caggcctgca gacctgccgc cccgaccacc agcgatgacg
    19081 actacttctc aatccgctgt agcgtggtga cgtggccttt atcggtgaca taggccttca
    19141 ccatgtcgcc ttcgaccacc ttatcgagct tggtgctctt gtccacatgc acccggacga
    19201 gctctccatc cgtattcctg atctggtaaa actccccgtc catcttcatc agcgtgccct
    19261 tcacggcatc cttcgtgatc cgctcgccca gggtcggcga cgcttccttg tccttcatag
    19321 gatcggccgc aaacgcgaag cctcctccac cggtgagcaa cgcggcaacc agacacattt
    19381 gaagagttcg cttcatcata caacctccca tttcgttagc cgaatcgata gaacctgatt
    19441 cagcctaacc cgcgtctgga agccgacaca ctggggaaag cccctgtcgc agggagcaat
    19501 ggcacgaagt caggcgatgg atgaatggaa aggagcactt cccgattcac gccacggcgg
    19561 ttttcaaatc ttggacaagg agagcaaaga gccgatcctg tatcacccga tcccgggcgc
    19621 gaagaatact ggacggatgg tacgtgagca gaatgcggga cgagacgggc tgctgaaaaa
    19681 tcgccctcgt tccatctgtg caggcagtta tacacaaaaa aaagctccgt cctctttcga
    19741 agacggagct tccaagaatt tacaattttt atatcaggcg ttcataacgt ttccgtcatg
    19801 cgtgcataat atttccattg caaattctta tgacctcacc ttatcgcaac cccctcaaca
    19861 tgggagttag gcaaagccct agaaatgtgg caaggaggca atgttcacgg cagagcactg
    19921 ttatctcttc acacggtcga ctgtttccgc atcgatcact gggaccgcct ttggattgtt
    19981 ccggtcaacc cgcacgatcc cgcggacccg aagctgttca ttctccacga ccggcttcgt
    20041 gacattgggc agacaggtgc ctggcgtgct gatgccgatc gtgcccgatc gatcatgtag
    20101 cgcaaacaac tggctgtcgt acaccgcgct cccgccacag cggcgcgttc cgcgatgaac
    20161 cggcaaggta ctcacggcct tcgccctccc ctccacggtg accactttgg catcatagtc
    20221 agcgggatgt tgcacaatgt tcttgatgcg caagcgatcg ccggccaaag ccatcgacac
    20281 cagcccaatg ctcaacgaca agcacaacag gctacggata agcgaatgca ttcccatgtg
    20341 tctacgcgtc ggtgtcagag cactgtcgca gggtggaaga ccgggaccgc tcatcacaac
    20401 gtgccagagg gatagctgga ttgatccgcg caagaagtga gggcattagg cggatgactg
    20461 aagctgctcg cgcttctgcc tcacggcttt cacacagcca tcataggcct cgatgaactg
    20521 ctgaatcccc tcattttcga gttgcacggt ggcgcaacga tagtcgatgc cgagatgttc
    20581 ga
//
LOCUS       DAOQPD010000068        20520 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1267_length_20520_cov_23.586074, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000068 DAOQPD010000000
VERSION     DAOQPD010000068.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 20520)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 20520)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20520
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1267_length_20520_cov_23.586074"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            261..3230
                     /locus_tag="PK063_14215"
     CDS             261..3230
                     /locus_tag="PK063_14215"
                     /inference="COORDINATES: protein motif:HMM:NF020039.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMP-30/gluconolactonase/LRE family protein"
                     /protein_id="HMZ98254.1"
                     /translation="MIKAWLLDEMFRFDRRYLTAEGSQSEWGAGDSVAEEEDLPPAPT
                     GVAAKAGNGRVMITWDAVPDAMYYNLYFMTTKGVQIKFSELTRPIASAEDFKTVIGVT
                     KEKGTCIEGAQSPFMHDDLANGTCYHYVVTVVTQKGESPESQEVMAIPAPYLIAKVIG
                     QEGVDEGEFSSPTGIAVDKDGNLYVADTDNHSIQKFDKEGKFLGRWGGEAGSAEGNYY
                     YPRGLTTNNDGQVYVADTGNNRVQRLDTDGNPMKSWGKFGFAWRGADMNKFDAPWGVT
                     TDQEGNIYVTDTNNARIQKFKGDGTPLLKWGRDGSFDGAFFFPRGVAVDFVGNTYVAD
                     EGNNRIQKFDTRGSFLTKWGREGSGPGQFKAPWGVTCDALGNVYVVDQGNHRIQKFDG
                     NGTFLCAWGNRGKTEGQLNFPSGVAVDKEGAVYVVDSGNHRVIKYVPTDEELNRGKEE
                     RERAQVVSEYPAPGNLAIKPGDTETFLSWMEVPKATSYNLYFHTSPNLTVEGGTKIEG
                     VTSPYNHTGLTNDQAYFYALTAVYEDGTESTLSEEVSATPVLIDITAPQTPYAVINHG
                     AFMTNSPEIVVTISATDLDTGVAAYYISENPMTPMAGTPGWVDVPPAIKFGATIPFIL
                     SPGDGQKTVIVWFKDLGNNISTPASATILVNTSGYLCVSKWGKPGRGASLLHGGEFMA
                     PMYGLAIDQQGSIFVVDNGNNRIQKFDRNGNFIILWGNFGAANANFHNPTGIACDAKG
                     DVYVVDTNNHRVQKFDGKLGGYMMKFGSRGNGEGQFNAPWGIAIDRVRGYIYVVDSAN
                     FRVQKFDMTGEFIMSWGSFGNGDGQFYFPRGIAVDQADGTVYVVDMGNHRVQKFDTST
                     NVLPQLLTKWGGSSEAGHASSPLAQEAGQLRSPWGIAVDGQGDVYVTDTGNHRLEKFD
                     REGNFISQWGGFGGGDGQFNFPYGIVVDSRGSVFAVDSGNTRVQQFMPAEEGSERLQE
                     EADAAAELGQIDKTTRV"
     gene            3269..4735
                     /gene="guaB"
                     /locus_tag="PK063_14220"
     CDS             3269..4735
                     /gene="guaB"
                     /locus_tag="PK063_14220"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HMZ98255.1"
                     /translation="MLEKEIRLGLTYDDVVLVPAKSQVLPTEVDTRTRLSRNIHLNIP
                     IVSAAMDTVTEARLAIAMAQEGGIGIVHRVLSPADQAAEIDRVKKSESGMILDPITIS
                     PDQTIRDAHDLMARYRISGIPVTKGGKLVGILTNRDLRFETRMDLKVSQVMKRDKLVT
                     APEGTSLEKAREILHEHRIEKLPVVNKQFELKGLITIKDIEKRIKYPNACKDAHGRLR
                     VGAALGVGPDTKDRVDLLVKAGVDVVVVDTAHGHSQAVLDTVKMVRKAHPKLDIIAGN
                     IATAQAAKDLVKAGVDAVKVGVGPGSICTTRMVSGAGMPQLTAIADCARALAGSGIPV
                     IADGGIKYSGDITKALAAGASVVMLGSLLAGTEEAPGETVLFQARTYKVYRGMGSIGA
                     MERGGGDRYGQGGRPTPKLVPEGIEGRVPYKGLLAPHIYQMVGGVKSGMGYCGCKTIP
                     DLQQKATFIRQTLAGLREGHVHDVIITKEAPNYRTDWE"
     gene            4823..6379
                     /gene="guaA"
                     /locus_tag="PK063_14225"
     CDS             4823..6379
                     /gene="guaA"
                     /locus_tag="PK063_14225"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HMZ98256.1"
                     /translation="MELWHDRILVLDFGSQYTQLIARRIREAQVYSQILPCTVSLATV
                     LAYRPKGIVLSGGPSSVYDKKAPKIPKQLFDQGIPILGICYGMQLVTHLQGGEVEKAP
                     HREFGRAELQLDDRSDLFKGIGRGGSTVVWMSHGDRIERMPPGFRSIAHTDNSPIAAM
                     KRHDAKQRIYCLQFHPEVAHTAEGATILKNFVYDICGCKPTWTMRSYVDTAVEQIRQQ
                     VGTERVICALSGGVDSSVAAALTHRAVGDQLTCIFVDNGVLRAGEREQVEKTFASQLH
                     LNMRILDRTTQFMTALKNVTDPERKRKIIGRLFIKNFEAESKKLKGIKYLVQGTLYPD
                     VIESVSFKGPSATIKTHHNVGGLPTKMKLKLVEPLRELFKDEVRVLGQELGLPDEIIW
                     RQPFPGPGLAIRVLGAVSKERLAILRGAETIVDQEIRAAGLYREIWQAFAVLLPIRTV
                     GVMGDQRTYEYVIAIRAVTSLDGMTADWAKIPNDVLGRMSSRIINEVKGVNRVVYDIS
                     SKPPSTIEWE"
     gene            6454..7710
                     /locus_tag="PK063_14230"
     CDS             6454..7710
                     /locus_tag="PK063_14230"
                     /inference="COORDINATES: protein motif:HMM:TIGR00093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HMZ98257.1"
                     /translation="MTVRLQKLIAGTGIASRRKAEELIVSGRVTINGHVVKELGTKVD
                     PERDHVKVDGKHLRAAQPYVYLILNKPKNVMSTLDDPEGRPTVKDFLRGVTVRVFPVG
                     RLDFDSEGLMLLTNHGDLAQALLHPRYHVPKTYLIKVKGVLDDTKIETLERGVKLEDG
                     FTAPAKINKVSRAESNSWLEVTIHEGRKHQVKRMIEAVGHSVIKLTRVRMGPLLLGEL
                     ASGEYRFLTDREANRLRELVEDRVARAEHPELDASGKPVRWMPPTEPAPPRPPKPERS
                     GRGPKSQRPDFGPRSVRGSGGANSGRPGRGALKRPLSPGAKFRRPAKTTGFQRPRPGA
                     VPQGDDRVPMANPPDSVRKPRPSGAGFQRGSFDRKSQGAGRKTPGNHSGSDQKFQQNR
                     RSGPSGSRPGQRGPARQSRNSTRRRA"
     gene            7707..9470
                     /gene="aspS"
                     /locus_tag="PK063_14235"
     CDS             7707..9470
                     /gene="aspS"
                     /locus_tag="PK063_14235"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HMZ98258.1"
                     /translation="MKIRTHRCGELTKAHVGQQVVLNGWVQRRRDHGMVLFIDLRDRT
                     GLTQVVFNAERNAAVHQAAHTLRSECVVSVTGQVMARPEESRNPHLPTGEIEIFVDAV
                     EILNEAKTPPFMIEDDIEITESLRLKYRYLDLRRPRMQRLLGLRHGIMQAVRAFLNAE
                     HFLEVETPVLTKSTPEGARDYLVPSRVNPGMFYALPQSPQLFKQVLMVSGVDRYYQIA
                     RCFRDEDLRNDRQPEFTQIDLEMSFVDREQVMSLMERMIVSVFKDAGGVQLPVPFPRM
                     TYAEAMGRYGSDKPDLRFDMPLYDVTAFAAKSDFKVFKDAATKGGLVKALIVSGGATI
                     ARSRIDALGETAKSFGAKGLAWLKVTAEGQLESVIAKFLDAQAFAAALPEAKPGDLVL
                     FGADKPAIVHDVLGRIRLLLGEELNLIDKTAWKPLWVTEFPLLDYSPEEKRYIFMHNP
                     FAAPMDEDIPFLDTEPLKARAKAYDMVLNGSEIGGGSIRNHRSDIQFRILDLLGIGKD
                     QAQAKFGFLLEALEYGAPPHGGIAFGLDRLIMLLGGADSIRDVIAFPKTQRAQCPLTE
                     APSAVSTDQLLELRIKLDLVE"
     gene            9488..10651
                     /gene="aroC"
                     /locus_tag="PK063_14240"
     CDS             9488..10651
                     /gene="aroC"
                     /locus_tag="PK063_14240"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HMZ98259.1"
                     /translation="MAGNTLGRVFTVTSFGESHGPAIGCVVDGCPPGLALSAEDIQQD
                     LDRRKPGTSRHVTQRQESDHVEILSGVFEGRTTGTPIALLIRNEDQRSRDYGNLIDTF
                     RPGHADYTYWQKYGIRDHRGGGRSSARETAVRVAAAAIARKWLYEKHGVMIRGYLSQL
                     GPIEAPFQSWDTVSRNPFFSANAEVVERLDSFMDELRKAGDSVGAKITTVAEHVPVGW
                     GAPVYAKLDADLAGAMMSINAVKAVEIGAGFASVAQRGSEHGDELTPEGFVTNHAGGI
                     LGGISTGQDVVVTIAIKPTSSIRVPRRSIDKTGKPQSVETNGRHDPCVGIRATPIAEA
                     MMALVLMDHALLHRAQNADVKTATPKIAGSINRLGSSASSKASSKPNAGPAEV"
     gene            10778..>11962
                     /gene="rnhA"
                     /locus_tag="PK063_14245"
     CDS             10778..>11962
                     /gene="rnhA"
                     /locus_tag="PK063_14245"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: protein motif:HMM:NF012235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI"
                     /protein_id="HMZ98260.1"
                     /translation="MIEIYTDGACSGNPGPGGWGVLLRLDGEETELCGGEPATTNNRM
                     ELLAVIEALQWFTHPVKARVYTDSQYVQKGISEWIHSWKRRGWKTASKEPVKNEDLWR
                     RLDALASGHTIEWHWVRGHNGHVDNERVDALARAGLEQSRRAGKPVTRPVATPVSAPV
                     KAAPVTVTSRPIVDIRHATVYRGETRVFSDFSFALREGEHAAIVGPNGAGKSTLLKLL
                     SGDVHPLALDDTTVQLFGQERWSVWDVRKQLGIVSHDLQRDYLICAEGLNVILSGFYA
                     SNDTYDHQTFSQEQVARAREVMRELRIDQLAGRTFGHLSTGEQRRFLLGRALVHDPAV
                     LVLDEPTSGLDLKACFQYLDLLRAQIRKGKTILLVTHHLHEIPPEIERVVLLKEGEVV
                     ADG"
     assembly_gap    11963..12062
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<12063..13075)
                     /locus_tag="PK063_14250"
     CDS             complement(<12063..13075)
                     /locus_tag="PK063_14250"
                     /inference="COORDINATES: protein motif:HMM:NF012318.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HMZ98261.1"
                     /translation="MSRSPLRYSHQLMRCALLTVASVAFVAGLFTVSASAFDAAALDR
                     AKLATIGVLEDTQDQRTPDKPGKILVRGTGFHLRDGYIVTARHAAEKQDVTTGTVIQK
                     QIHVLTTDLHEIPADLVGDSAFMDVVVYRVAEAHRAKLLANVAFAPGDVQPGQDVFTV
                     GYPMGWGPTMSFGHLGNTNTFLQTVDTRLIQADVAACSGNSGGGLFNDKGEVVGIMHA
                     IIQTERDDSTAHCSRMAFAIPALLAERIVTAALDGKPLTFSKMGIHMVAVKDGTRWRM
                     AVKDVMEPAKSAGIQKHDVIIAVDDTDIQDAAHLKNYLIERTKPGQQVSVKVRRIDTN
                     LTFT"
     gene            13112..13759
                     /locus_tag="PK063_14255"
     CDS             13112..13759
                     /locus_tag="PK063_14255"
                     /inference="COORDINATES: protein motif:HMM:NF015782.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Slp family lipoprotein"
                     /protein_id="HMZ98262.1"
                     /translation="MQYKPGPVPEEMNVLCACAVVSGAGLGYTEVMKKILQALIIGVA
                     VVAAGCATPVIPESLEPQVDKAVTFSQIVESPDSYRGKVVVVGGEILKAKALKGGTQL
                     EVLQLPLDSDQEPVTDRMESKGRFLALQKEFLDPATIAEGTRVTVVGEVTGSSVEKMD
                     EADYRFPTLDVKHLHRWDAKRAEERSAPGPWWNVFGGVGFGGGGTRSGGGISIGF"
     gene            complement(13825..14691)
                     /locus_tag="PK063_14260"
     CDS             complement(13825..14691)
                     /locus_tag="PK063_14260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HMZ98263.1"
                     /translation="MRWQGQRESQNIEDRRGMGAARSGAGIGLGGLVLVLAVSFLTGT
                     NPLTLLNLLTGVQEITGPAEPDRPGPTGAPSDNLGKFAAVVLADTEDTWRALLPQMGS
                     AYQDPQLVLFTGAVRSACGTASSAVGPFYCPGDRKVYLDLSFFQELARRLGAPGDFAQ
                     AYVIAHEIGHHVQNLLGLADQVTRQQQRSSPAERNALSVRMELQADCFAGVWGYHASR
                     SRQLIEPGDFEDGLHAAAAIGDDRLQQMGQGYVQPESWTHGSSEQRVAWLRRGLQSGD
                     PQVCDTFAGGRS"
     gene            14923..15543
                     /locus_tag="PK063_14265"
     CDS             14923..15543
                     /locus_tag="PK063_14265"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98264.1"
                     /translation="MWSHLSITHARRGTLFQLCSVALIALLYLDGCRPAPVATLPPTL
                     KPSLAWPECPKIGGMYELQGEALPGSMNFYRNRDSKLTLNAMLGVAAPADLAQESVRV
                     ELVHDDTLELVNRYDGAITAHQLDLQPEDRVVCEPNRIRIHRTRAEGGVAEEPLRNIS
                     EYAQELTVEGDGSLLVKTRILNQSKSAFWSTPIPPEEYAARFRRLD"
     gene            15665..16258
                     /locus_tag="PK063_14270"
     CDS             15665..16258
                     /locus_tag="PK063_14270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HMZ98265.1"
                     /translation="MPVTARRPSRTLALHKPYDVLPCFTDPDGRPTLSRYIDVPDVYP
                     AGRLDRDSEGLLLLTSDGTLAHHITDPRHLLAKVYLVQVERIPDAAALKRLEAGVLLG
                     GKRTRPAQARLLEEAPRLPDRPVPIRFRKHIPTAWLELTLREGMNRQVRRMTAAVGHP
                     TLRLVRVAIGSITLGDLQPGEWRELTKQEVADMFHSA"
     gene            16555..17079
                     /locus_tag="PK063_14275"
     CDS             16555..17079
                     /locus_tag="PK063_14275"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98266.1"
                     /translation="MTNRWSLLLLLGIGFSHVTPVFGANPDSVPVADMRHIKKFVAVE
                     VQTQGTAEKLGISAAELTDVTRVTLLNKVPGIVLEASSGPSLDATERLNQLGFFTCEV
                     WTVGEQYIAAYHVDCNAGSYTPQKTPGSLWNQAILGYGPRDEVSDAVRKGVRAMVELF
                     ASTFAGVRADGGGR"
     gene            complement(17784..18692)
                     /locus_tag="PK063_14280"
     CDS             complement(17784..18692)
                     /locus_tag="PK063_14280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HMZ98267.1"
                     /translation="MPPRETNYFTENKKFYVVNYSDSPFNVSRDLRQDEWRLSVKGEV
                     KNPLSLGWRELLNRENFEQISTLMCIDTLPGGDSLGNARWRGISLKKLLQEAGVDEDT
                     TRDIVFRGADAYDDSIPLTRAMQDDVMLAFLMNGEKLSKEHGFPLRLLVPGLYGIKNV
                     KWIVEIEAYAGDYKGYWQRKGWTDDGTIKTFSRIDSPGHYQTLRGPVQRFRGIAFGGP
                     NSISRVEISLDAARTWDSCEIETPMSPYSWVIWNYTWHPPKRGKYQVAVRAVDSKGQP
                     QIAELIRPQPAGSSGLHTIIADVESV"
     gene            19135..>20520
                     /locus_tag="PK063_14285"
     rRNA            19135..>20520
                     /locus_tag="PK063_14285"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT         4413 a         5442 c         6199 g         4366 t
ORIGIN      
        1 tttgctgccg ggagtgcaga gcctatgata ttcgaaagaa atgcgtccat ccagctttgg
       61 ggggatggag acccaccggc ctctcgacct gatagaacgg gcttccggtg atcgatcgca
      121 ctgcgacgga attgtattga acaagcagtg aagcgccccg gtcctgcctt gactcccttc
      181 ttttcgcttt gctagactgc ccgatctaag ttattgaaac atccgccaat cttcaccaat
      241 ctcgtaccac gaggaacacc atgatcaagg cttggctgct cgacgaaatg tttcggtttg
      301 accgtcggta tctcaccgcg gaaggaagtc agagcgagtg gggcgccggg gactccgttg
      361 cggaggagga agatctgcct cccgccccga ctggagtagc cgccaaagcc gggaatggcc
      421 gggtgatgat tacctgggat gccgtgccgg acgccatgta ttacaacttg tacttcatga
      481 cgacgaaagg cgtgcagatc aagttttcag aactcacccg ccctatcgcc agcgcagagg
      541 attttaaaac cgtcatcggc gtcacgaagg aaaaagggac ctgtatcgaa ggggctcagt
      601 cgcccttcat gcatgacgat ctggcgaacg gaacctgtta tcactatgtc gtgacggtgg
      661 tgacgcagaa aggggaaagc cccgagtctc aagaagtcat ggcgattcca gctccgtacc
      721 tgattgcgaa agtgatcggc caggaaggtg tggacgaagg agagttcagc tctccgacgg
      781 gcatcgcagt ggacaaggac ggcaatctct acgtggccga tacggacaat cattccattc
      841 agaaattcga taaagagggg aagtttctcg gccgttgggg cggagaggcg ggtagcgcgg
      901 aaggcaatta ttattatccc cgcggcctca cgaccaataa cgacggccag gtctacgtag
      961 ccgataccgg taacaatcgt gtgcagcggc tcgataccga cggcaatccc atgaagtcct
     1021 ggggcaagtt cggattcgcc tggcgcgggg ccgatatgaa taagttcgac gcgccctggg
     1081 gtgtgactac tgaccaagaa ggcaatattt acgtcaccga taccaacaat gcccgcattc
     1141 aaaaattcaa aggcgacggc acgccgttgc tcaagtgggg acgggatggc agtttcgacg
     1201 gcgcgttctt ctttccccgt ggagtcgcgg tggacttcgt tggaaatacg tatgtggccg
     1261 atgaaggcaa caaccgtatc caaaagtttg atacgcgcgg cagctttttg accaagtggg
     1321 gacgcgaggg tagcggtccc ggtcagttca aggcgccctg gggcgtcacc tgcgatgcct
     1381 tgggcaacgt gtacgtggtg gatcagggca atcaccgcat tcagaagttt gacggaaacg
     1441 gcaccttcct ctgtgcctgg ggcaatcgcg gaaaaacgga aggtcagctg aactttccgt
     1501 caggtgtcgc cgtcgataag gaaggcgcag tctatgtcgt ggatagcggc aatcaccgcg
     1561 tcatcaagta tgtgccgacc gatgaagaat tgaatcgcgg aaaagaagag cgtgaacggg
     1621 ctcaggtcgt cagcgaatac cctgctcccg gcaatctggc gatcaagcct ggtgatacgg
     1681 aaacgttcct gagttggatg gaggtgccga aagccacttc ctacaatctc tatttccata
     1741 cctctcccaa cctgaccgta gaaggcggta cgaagatcga gggtgtgacg agtccctaca
     1801 atcataccgg gctgaccaac gaccaagcct acttttatgc gctgacggca gtctatgagg
     1861 acggcacaga gagtacgttg tcggaggaag tttcggcgac accggtgctg atcgacatca
     1921 cggccccgca aacgccgtat gccgtgatca atcatggcgc gttcatgacg aactcaccgg
     1981 aaattgtcgt gacgatttcc gcgaccgacc ttgatacggg ggtggccgcc tactatatct
     2041 ctgaaaaccc gatgactccg atggcgggaa cgcccgggtg ggtggacgtt ccgccggcca
     2101 tcaagttcgg cgcgacgatt cccttcattc tttccccggg cgatgggcag aagaccgtca
     2161 tcgtctggtt taaggatctc gggaacaaca tttcgacccc ggcaagcgcc accattctcg
     2221 tcaatacatc cggctatctc tgcgtctcca agtggggcaa gccgggccgc ggcgcatcac
     2281 tattgcacgg cggcgagttc atggcgccga tgtacggtct ggccatcgat cagcagggat
     2341 ccatttttgt cgtcgacaac ggcaacaacc gtattcagaa gtttgaccgt aacggcaatt
     2401 tcatcattct ctggggaaac ttcggtgcgg ccaacgccaa ttttcacaat ccgaccggta
     2461 ttgcctgcga tgccaagggc gatgtctacg tggtcgatac gaacaatcac cgcgtccaga
     2521 aattcgacgg caaattgggc ggctacatga tgaagttcgg gtcgcgtgga aacggcgaag
     2581 gccagttcaa tgcgccgtgg ggcatcgcga tcgatcgggt gcgcggctat atctacgtcg
     2641 tcgatagtgc gaacttcaga gtccagaaat tcgacatgac cggcgaattc attatgtcgt
     2701 ggggaagttt cggcaacggc gacggacagt tctatttccc gcgcggtatc gccgtcgatc
     2761 aggcagacgg caccgtctat gttgtcgata tgggcaacca tcgcgtacag aagttcgaca
     2821 ccagcacgaa cgtcctgcct cagttgttga cgaaatgggg aggaagttct gaggccggcc
     2881 atgccagcag tccgttggcg caagaggcgg ggcagcttcg ttccccctgg ggtatcgccg
     2941 tggatggaca aggtgacgtg tatgtcacgg ataccgggaa ccatcgtctt gaaaagttcg
     3001 atcgtgaggg gaactttatt tctcagtggg gtggcttcgg cggcggcgac ggacaattca
     3061 acttccccta cggaattgtg gtggattcac ggggaagcgt attcgccgtc gatagcggca
     3121 acaccagagt gcagcaattt atgccggcag aagaaggcag cgagcggttg caggaagaag
     3181 cggatgccgc agccgaactg gggcagatcg ataaaaccac gagagtctaa gggcagcggg
     3241 caggaagccc gggagagggt ggcaacggat gttagagaag gagattcggc tcgggttgac
     3301 ctatgacgac gtcgtcctgg ttccggctaa atcgcaagtt cttccgaccg aagtcgatac
     3361 ccgcacgcgc ctctctcgga atatccatct gaatattccc atcgtgagtg ctgccatgga
     3421 caccgtgacg gaagcgcggt tagccatcgc aatggcccaa gagggcggca tcggcattgt
     3481 gcaccgtgtg ctctcgcctg ccgaccaagc ggctgaaatt gaccgggtca aaaagtctga
     3541 aagcgggatg attcttgatc ccatcaccat ctcgcctgat caaaccatcc gtgatgctca
     3601 cgacctgatg gcccgatacc ggatttccgg catccctgtg acgaagggcg gtaaattggt
     3661 cggcatcctg acgaatcgcg atctgcgatt tgagacgaga atggatctga aggtctcgca
     3721 agtcatgaag cgtgacaagc tcgtcactgc gccggaaggc accagcctgg aaaaagcccg
     3781 cgagatcctg cacgagcacc ggattgaaaa gttgccggtg gtgaacaagc agttcgaact
     3841 caaaggcttg atcaccatta aggacattga aaagcggatc aagtatccca acgcctgcaa
     3901 ggatgcccac ggccgcttgc gtgttggtgc ggcgcttggc gtggggcctg atacgaagga
     3961 tcgagtggac ctgctggtaa aggccggcgt agacgtcgtc gtcgtggata ccgcccatgg
     4021 gcattcccag gcggtgcttg atacggtcaa aatggtcaga aaagcccatc cgaaactgga
     4081 tatcattgcc ggcaacattg caaccgcaca ggcagcgaag gacttggtga aggcaggtgt
     4141 ggatgcagtt aaagtcggcg tcgggcccgg ttcgatttgc accacacgaa tggtgtcggg
     4201 ggccggcatg ccccaattga cggccatcgc cgattgcgcc agggctttag ccggatcggg
     4261 aattccggtg atcgcggacg gcgggattaa gtattccggc gatatcacga aagccttggc
     4321 agcgggcgcc tcggtcgtta tgctcggaag tttgttggct ggtacggaag aagctccagg
     4381 cgaaacggtc ttgttccaag cgcgcaccta caaggtttac cgtggaatgg ggtccatcgg
     4441 ggccatggag cgtggcggtg gggatcgtta cgggcagggt ggtcgtccga caccaaaact
     4501 ggttccggaa ggtatcgaag gccgcgtacc gtacaaaggt cttctcgcgc cgcacatcta
     4561 tcagatggtt ggtggtgtga aatccggtat gggatattgc ggatgtaaga ccattcccga
     4621 tttacaacag aaggcgacct tcattcgcca gacattggcc gggctccgcg aaggccacgt
     4681 acatgacgtg attattacca aagaagcgcc caactatcgc actgattggg aataacacgc
     4741 gtagaacggg cgagaggcgt tgccttcccc gttttcgtca gcccccgcac tgaacctcta
     4801 atctcgtaca ccgcgcacac tcatggaact ttggcacgat agaattcttg ttctcgattt
     4861 cggctcccag tacacgcaac tcattgcacg acgtatccgt gaagcgcagg tctattcgca
     4921 gatcctgccc tgcacggttt cgctcgcgac agtgttggcc tatcggccca aaggtatcgt
     4981 cctgtccggc ggtccctcga gtgtctacga caagaaggct ccgaaaatcc ccaaacaact
     5041 ctttgatcaa ggcatcccga tacttggaat ctgctatggg atgcagttgg tgacgcatct
     5101 ccagggcggt gaagtggaga aagcgccgca ccgagaattt ggccgggccg agctgcaact
     5161 tgacgatcgc tcggatctct tcaagggtat tggacgcggt ggatccacgg tggtgtggat
     5221 gtcgcacggg gaccgcatcg agcggatgcc gccaggtttc cgttccattg cccatacgga
     5281 caattctccc attgcggcga tgaagcggca tgatgccaaa cagcgtattt attgtttgca
     5341 gtttcacccc gaggtagccc ataccgccga aggtgccacg attctcaaga attttgtcta
     5401 cgacatctgc ggctgcaaac cgacctggac gatgcgctct tatgtcgaca ctgctgtgga
     5461 gcagattcgt cagcaggtcg ggacggagcg ggtgatttgt gccttgagcg gtggggtgga
     5521 ttcgtcggtg gcagcggctc tgacgcatcg tgcggtcggc gatcaattga cctgtatttt
     5581 cgtcgataac ggggtgttgc gtgccggcga gcgtgagcag gtcgagaaga cctttgcgtc
     5641 ccaactacac ctcaacatgc gcatcctcga tcgtacgacc cagttcatga cggcgttgaa
     5701 aaatgtgact gatccggagc gcaagcggaa gatcatcggc cgcctcttca tcaagaattt
     5761 cgaagccgaa tccaagaagc tcaagggcat caaatatctt gtgcagggca cgctgtatcc
     5821 cgatgtcatc gaaagcgtca gcttcaaagg gccttccgcg accatcaaga cccaccataa
     5881 cgtcggcggg ttgccgacca aaatgaaact gaagctggtt gagccgctgc gcgaattgtt
     5941 caaggacgaa gtgcgggtgt tggggcagga gcttggcttg ccggatgaga tcatttggcg
     6001 gcagccgttt cccggtccgg ggttggcgat ccgggtgctc ggcgcggtat ccaaagaacg
     6061 attggccatc ttgcgcgggg ccgagacgat cgtcgatcag gaaattcgcg ccgccggact
     6121 ctatcgggaa atctggcagg cctttgccgt gttattgccg atccgaactg tcggcgtgat
     6181 gggcgatcag cgaacctacg agtatgtgat tgcgattcgg gccgtcacaa gcctcgatgg
     6241 catgaccgct gactgggcca agattccgaa cgacgtactg ggtaggatgt cgagtcggat
     6301 catcaatgaa gtgaagggcg tcaaccgcgt cgtctatgac atcagctcta aacctccgag
     6361 cacgatcgag tgggaataac agtgctagat atgccaccta aacggtgagt cacggcgatc
     6421 cctttacctg atacgttgtc cctttcacag catatgaccg ttcgtctgca aaaactcatt
     6481 gccggtaccg gtatcgcttc ccggcgaaaa gctgaggaat tgatcgtgtc cggacgcgtg
     6541 accatcaacg gccacgtggt gaaagagctt ggcactaaag tcgatcccga gcgcgatcat
     6601 gtcaaagtgg atggcaaaca tctgcgagcc gctcagccct atgtctattt aatcctcaat
     6661 aagcccaaga acgtcatgtc caccctcgat gatccggaag gtcgtccgac cgtgaaggat
     6721 tttttgcgtg gcgtgacggt gcgcgtgttc ccggtcggcc gattggattt cgatagcgaa
     6781 ggactcatgt tgctcaccaa tcatggtgat ttagcccagg cgctgctcca tccccgctac
     6841 catgtgccga agacctatct catcaaggtc aagggtgtcc tcgacgatac gaaaatcgag
     6901 acgcttgaac ggggagtcaa actcgaagat ggtttcaccg ccccggcgaa gatcaataaa
     6961 gtcagcaggg ccgaaagcaa ttcgtggctg gaagtcacta tccatgaggg ccgcaaacac
     7021 caggtcaagc ggatgatcga ggcggtcggc cattcggtca tcaagctgac acgtgttcgg
     7081 atggggcctc tcttgctggg cgaactggca tcgggggaat atcggttttt aaccgaccgt
     7141 gaggccaatc ggttacggga actggtggaa gatcgtgtgg caagggccga acatccggag
     7201 ttggacgcgt cgggcaaacc ggtgcgctgg atgcccccta cagagcccgc ccctccacgc
     7261 ccacctaagc cggaacgttc cgggcgtggc cccaaatctc aacgtccgga cttcggacct
     7321 cgatcagttc gaggttcggg tggcgcgaac tctgggcgtc ctggtcgtgg tgcgctgaaa
     7381 cgcccgctca gtcctggggc gaagttccgc cgtcctgcaa agacaacagg ctttcaacgg
     7441 cctcggccgg gtgcggtccc tcaaggcgac gatcgtgtcc caatggcgaa tcctcccgat
     7501 tcggtgagga agcctcggcc ttcgggagca ggttttcagc ggggctcatt cgacagaaaa
     7561 tctcaaggcg ctgggcgaaa gacgccaggg aatcattctg gctcggacca gaaatttcaa
     7621 cagaatcggc gaagcgggcc ttctggctcg cgcccaggcc agcggggccc tgcaaggcag
     7681 tcgcggaatt caacgcggag aagagcatga agatcaggac ccatcggtgc ggggagttga
     7741 ccaaggcaca cgtcggtcaa caggtcgtat tgaacggctg ggtgcaacgg cgtcgtgacc
     7801 acggcatggt gctgttcatc gatttgcgtg atcggacagg attgacgcag gtcgtgttca
     7861 acgctgagcg gaacgccgct gttcatcagg cggcacatac actgcggagt gaatgcgttg
     7921 tgtcggtcac cggtcaggtc atggctcgcc ccgaggagtc tcgcaacccg catttgccga
     7981 cgggcgagat tgagatcttc gtcgatgccg tggagattct gaacgaagcg aagacgccgc
     8041 ctttcatgat cgaagacgac atcgagatca ccgagtctct gcggttgaaa tatcgctatc
     8101 tcgacctgcg gcgcccacga atgcagcggt tgctggggtt gcgtcacgga atcatgcagg
     8161 ccgtgcgtgc atttttaaat gccgagcatt ttctcgaagt ggaaacaccg gtcctgacga
     8221 agagcactcc ggaaggcgcg cgggattatc tggtgccgag tcgcgtcaat ccgggcatgt
     8281 tctatgcgct gccgcagtcg ccgcagttgt ttaagcaagt cttaatggtc agtggtgtcg
     8341 accggtatta ccagattgct cgttgcttcc gtgacgaaga tctgcgcaac gatcgccagc
     8401 cggaatttac ccagatcgat cttgaaatgt cgttcgtaga ccgcgagcag gtcatgtcgc
     8461 tcatggagcg gatgatcgtg tctgtgttca aggatgccgg tggcgtgcag ttgcccgtcc
     8521 cgttcccacg aatgacctat gccgaagcca tggggcgtta tggctccgac aaaccggatc
     8581 tgcgcttcga tatgccgttg tacgatgtca cggcctttgc ggcgaagagt gactttaaag
     8641 tgtttaaaga cgcggcgacc aaaggcgggc tcgtcaaggc tttgattgtg tcgggcgggg
     8701 cgaccatcgc gcggagccgt atcgatgcgc ttggtgagac ggccaaaagt ttcggcgcca
     8761 aaggcttagc ttggctgaag gtcaccgcgg aagggcaatt ggaatccgtg attgccaaat
     8821 ttctcgatgc ccaggccttt gccgcggcct tgccggaggc aaagcccggg gacctggttc
     8881 ttttcggagc ggataagccg gccatcgtgc atgacgtgct ggggcggatc cgcttgttgc
     8941 tgggtgaaga actgaatttg atcgataaaa ctgcctggaa gcccctctgg gtgaccgagt
     9001 tcccattgct ggactattcg ccggaagaga agcgctatat cttcatgcac aatccttttg
     9061 cggcgccgat ggacgaagat atcccgttcc tcgacacgga gccattgaag gccagagcga
     9121 aggcgtacga tatggtgctc aacgggagtg aaatcggcgg cggtagcata cgtaatcatc
     9181 gcagtgatat tcagtttcgg attctcgacc tgttgggtat cgggaaggat caggcgcagg
     9241 ccaagttcgg cttcttgctg gaagccctgg agtacggcgc gccgccgcac ggcgggatcg
     9301 ccttcggctt ggatcgattg atcatgctcc tgggcggggc cgattctatt cgtgatgtca
     9361 ttgccttccc gaagacccaa cgcgcgcagt gcccgctcac cgaggctcca tctgctgtca
     9421 gtaccgatca gttgctggaa cttcgcatta agctggatct tgtcgaatag caggagccat
     9481 cccattcatg gccggcaaca cgttgggccg agtcttcacc gtcacctcat tcggcgaaag
     9541 ccatggaccg gccatcggct gcgtcgtcga tggctgtccg ccggggctgg cactctccgc
     9601 cgaagatatt cagcaggatc tggatcgccg caagcccggc acgtcccgcc atgtcacgca
     9661 gcggcaggaa tccgaccacg ttgaaatcct atccggggtt ttcgaaggac ggacgacggg
     9721 tacgccgatt gccctcctca tccggaacga agatcaacgc agccgggatt atgggaacct
     9781 catcgacacc ttccgtcccg gccatgccga ctacacctat tggcagaaat atggcatccg
     9841 cgatcatcgg ggcggcgggc gttcctcagc ccgtgaaacc gctgtgcggg tggcggctgc
     9901 tgcgatcgcg agaaagtggc tatacgaaaa acatggcgtc atgatccgtg gctatctcag
     9961 tcaactgggc ccgatcgagg ctccgtttca aagctgggac acggtgagca ggaatccgtt
    10021 cttctctgcc aacgccgagg tggtcgaacg gctcgactcc tttatggacg aattgcggaa
    10081 agcgggtgac tctgtcggtg cgaaaatcac gacggtcgcg gagcatgtgc cggtagggtg
    10141 gggtgctccg gtgtatgcca aactggatgc ggacctggcc ggcgccatga tgagcatcaa
    10201 tgcagtgaag gcagtggaaa tcggggccgg ttttgcttca gtcgcccagc gaggttccga
    10261 gcatggggac gaactcacgc ctgagggatt tgtcaccaat catgcaggcg ggattctcgg
    10321 tggaatttca accgggcagg atgtggtggt gaccatcgcc atcaagccga cctcgagcat
    10381 tcgcgtgccg cgtcgttcga tcgataaaac cggcaagcca cagtccgtcg aaaccaatgg
    10441 ccgtcacgat ccctgtgtcg gtattcgtgc cactcctatt gccgaagcca tgatggccct
    10501 cgtgctcatg gaccatgccc tcctgcatcg cgcccaaaac gccgatgtga aaactgcgac
    10561 tccgaagatc gccggctcca tcaacaggct tggttcttca gccagctcaa aagcatcctc
    10621 gaagcccaac gctggccctg ccgaagtata gcggcctgtc atgtctgcgt cgtctgctga
    10681 cttctgctcg tgatgacacg ggggagatat ccgtggatgc gcactgagga gagtgattgg
    10741 tgaagtggtt ggtgagcgct tagaggaacg tcctcgcatg atcgagatct acacagacgg
    10801 cgcctgcagc ggaaaccccg gccctggtgg ctggggagtt ttgttgcgcc tggacgggga
    10861 agaaacggaa ctctgtggag gcgagccggc cacgaccaac aaccggatgg agttgctcgc
    10921 ggtcatagag gcgctgcagt ggtttacgca cccggtgaag gctcgagtct acacggattc
    10981 tcagtatgtg caaaagggca tcagcgaatg gatccatagc tggaagcgcc ggggctggaa
    11041 aactgccagc aaagagccgg tcaaaaatga agatctctgg cgtcgtctgg atgcattggc
    11101 ttccggccac accatcgaat ggcattgggt caggggacac aatggccatg tggacaacga
    11161 acgagtggac gcgctggccc gcgccgggct cgaacagtcg cgtcgagccg gaaagccggt
    11221 tacgcgtccg gttgcgactc cggtttccgc acccgtcaag gcggcaccag tcacagtaac
    11281 ttcccgcccc attgtggata ttcggcacgc gaccgtttat cgaggagaga cccgcgtctt
    11341 ttcggatttt tccttcgcgc tgcgtgaagg agaacatgcg gcgatcgtcg gtcctaatgg
    11401 cgccggaaag tctactctgc tgaagttatt atctggtgat gttcatcccc tggcactcga
    11461 tgacaccaca gtgcagctgt tcggtcagga gcgctggagt gtgtgggacg ttcggaagca
    11521 gttgggaatc gtgtcgcacg acctgcagcg ggactatttg atttgtgctg aaggcctgaa
    11581 cgtcattctg tccggctttt atgcgagcaa cgacacgtat gaccaccaaa ccttcagcca
    11641 ggagcaggtc gctcgtgccc gggaggtgat gcgggaattg cggatcgacc agttagctgg
    11701 ccgcaccttc ggtcatctgt cgaccggtga acaacggcgg tttctcctcg ggcgcgcgct
    11761 cgtgcatgat ccagctgtgc tggtgctgga tgagcccacg agcgggctcg acctcaaagc
    11821 ctgttttcaa tatctcgatc tgctgcgcgc gcaaatccgg aaagggaaga cgattctgct
    11881 ggtcacgcac catctccacg aaattccacc cgagatcgaa cgcgtggtgc ttctcaagga
    11941 gggtgaagtg gttgcggatg ggnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12061 nngtaaaagt gaggttggta tcgatgcggc ggacttttac gctcacttgt tggccgggct
    12121 tggtccgttc aatgagatag tttttcaaat gcgcggcgtc ctgaatgtcg gtgtcatcta
    12181 cggcaataat gacatcgtgc ttttgaatgc cggcggactt ggccggttcc atgacgtctt
    12241 ttaccgccat gcgccaccgg gtgccgtctt ttaccgctac catatgaatg cccattttgg
    12301 agaaggtcag cggcttgccg tccaacgcgg cggtgacgat gcgttcggcg agcagcgcgg
    12361 gaatggcgaa ggccatgcga ctgcagtgag cggtggagtc gtcgcgttcc gtttgtatga
    12421 tggcatgcat gatgccgacg acttcaccct tgtcgttgaa gaggccgcca ccggagttgc
    12481 cgctgcaggc ggcgacatcg gcttgaatga gccgtgtatc aaccgtctga aggaacgtgt
    12541 tcgtattgcc caggtggccg aacgacatgg tggggcccca gcccatggga tacccgacgg
    12601 taaagacatc ctgccctggc tgcacgtcac cgggagcaaa ggccacgttg gccaagagtt
    12661 tggcgcgatg tgcttcagca acgcggtaga cgacgacgtc catgaaggcg ctgtcaccaa
    12721 ccaggtctgc gggaatctca tggaggtcgg tcgtcaacac atggatctgt ttttgaatga
    12781 cggtgccggt tgtgacatcc tgcttttccg ccgcatggcg ggcggtcacg atgtagccat
    12841 cacggaggtg aaacccagtg ccacgcacta aaattttccc cggtttgtca ggcgtacgct
    12901 gatcttgcgt gtcttccaga acgccgatgg tcgccagctt ggcgcgatct agtgctgctg
    12961 catcaaatgc cgaggccgag accgtgaaga ggccggcgac gaacgcaacg gaggcaaccg
    13021 tcagtagcgc acaacgcatg agctgatgtg agtaacgaag cggggagcgt gacatacgaa
    13081 ctattccttt cgtgtggatg tcgtcaggtc tgtgcagtat aaaccagggc ccgtgccgga
    13141 ggaaatgaat gtgttgtgcg cctgcgccgt agtatcaggc gccgggctgg gctatactga
    13201 ggtgatgaaa aagatccttc aggcactgat cattggagtg gcggtcgttg ccgctggctg
    13261 cgcgacgccg gtcattccgg aatcactgga accgcaggtc gataaagccg tgacgttcag
    13321 ccagatcgtt gaatcccccg attcctatcg cggcaaagtc gtcgtcgttg gtggagagat
    13381 tctgaaggcg aaggccctga agggaggcac gcagctggaa gtcctgcagc tgccattgga
    13441 tagtgaccag gagcccgtga ccgaccggat ggaatccaaa gggcgatttc tcgccctaca
    13501 aaaggagttt ctcgatccag ccaccattgc cgaaggcacc agagtgacgg ttgtcggaga
    13561 ggtaacgggg agctcagtgg aaaagatgga tgaagccgac tatcgtttcc ctacgctgga
    13621 cgtcaaacat ctccatcggt gggatgcgaa acgagcagag gaacgttccg cgcccggtcc
    13681 ctggtggaac gtgttcggtg gtgtgggatt cggcgggggc ggcacccgca gtggcggcgg
    13741 catcagtatt ggattttaac tcgccggcag tcccctagtc tcttcttccg ctctgtactc
    13801 cgttatccag ccttctgcac tggtctaaga tcgcccgccg gcaaaggtat cgcacacttg
    13861 aggatcgcct gactgcagac cacgccgcag ccaggccacc cgttgctcgg atgacccgtg
    13921 agtccagctt tccggttgca cgtaaccctg ccccatttgt tgaaggcgat cgtcaccgat
    13981 ggctgcagcg gcgtgcagtc cgtcctcaaa atcgccgggt tcgatgagtt gccgactacg
    14041 actggcatgg tatccccaca cacccgcaaa acaatcggct tgtaattcca tgcggacgga
    14101 aagcgcgttg cgttcggccg gggaactgcg ttgttgctgc cgggtaacct ggtcagcgag
    14161 gcctagcaga ttctgtacgt gatgcccgat ttcatgggcg atgacatagg cctgggcaaa
    14221 gtcgccgggg gcgccaagcc gtcgggccag ttcctgaaaa aatgagaggt ccagatagac
    14281 cttacggtcg ccgggacagt aaaagggccc cacggcggat gaggcggtgc cgcaggcgga
    14341 ccgtacagca cctgtgaaca gcaccaactg cggatcttga taggcactgc ccatttgcgg
    14401 gagcagcgcg cgccaagtgt cttccgtatc ggccaggacg acggcggcaa acttcccaag
    14461 attgtcgctt ggcgcaccgg ttggtccggg gcgatctggc tccgcgggac cggtgatctc
    14521 ctgcacgccg gtgaggagat tgaggagcgt gaggggattg gtgcccgtca gaaagctgac
    14581 ggcgagcacg agcacaagcc cgcccaatcc tatacccgcg ccggaccggg ccgcgcccat
    14641 gcctcggcgg tcttcaatgt tctggctctc gcgctggcct tgccatcgca tgattggact
    14701 ccttggttgc ggcactgacc gacggtcgtc ttttagctgt gggaagagtc agctgatgga
    14761 aacatatttc gcatggctgg gcaaggctct tgccaaccag atagccgagg agctgcgggg
    14821 ggatgtctca gattggcgca gcccgtgaac atttcggaac agggggcctt ttccccttct
    14881 tctctctaga caggccggtg agcgcttcgc tagacttgaa gaatgtggtc gcatctttcc
    14941 atcactcatg cccgacgagg aacgctcttt cagctctgtt cggtggcgct gattgcattg
    15001 ttgtatctcg acggatgccg tccagccccg gtggcgactc tgccaccgac gttgaagccg
    15061 agtttggcgt ggccggaatg tccgaagatc ggcgggatgt atgaactgca aggagaagcg
    15121 ttgcccgggt cgatgaattt ttatcggaac cgcgatagta agctcacgct gaatgcgatg
    15181 ttgggagtgg ctgcgcctgc ggaccttgcg caggagtctg ttcgcgtgga gttggtgcat
    15241 gacgacacgc tggagctggt caatcggtat gatggagcca ttaccgcgca tcagttagat
    15301 ttgcagccgg aagatcgagt ggtctgtgag cctaatcgga tccggatcca tcgaacccgt
    15361 gcggagggtg gtgtggccga ggaaccgctg cggaatattt ccgaatatgc ccaggaattg
    15421 accgtggaag gagacgggag cttattagtg aaaacccgta tcctcaatca gagcaagtct
    15481 gcattttgga gcacccccat ccctcctgag gagtatgcgg cgcgcttcag gcggctcgac
    15541 tgatcgcgag agtctggacc ttccttccgt atcggtgacc tctcgtgcac atgggtattt
    15601 catcctgcgt cacctgttct gtcccctaca gagccattac gactgaagtc ctggagggca
    15661 gcgcatgcct gtgacggctc gccgtccttc acgtacactc gcccttcaca agccctacga
    15721 cgtcctgcct tgtttcaccg atcctgatgg gcgccccaca ctgagccgtt acattgatgt
    15781 gccggatgtc tatccagccg gccgattgga tcgtgatagc gaaggactcc tcctcctgac
    15841 ttccgacgga acgctggcgc atcacatcac cgatccccga catcttctcg caaaagtgta
    15901 ccttgtccag gttgagcgta ttcccgatgc ggcagcgcta aagcgtcttg aagccggcgt
    15961 gctgctcgga gggaagcgca cacggccggc acaggcccgc cttctcgagg aagctccgcg
    16021 tttgcctgac cggcccgttc caattcgatt tcgaaaacat attcccacag cttggttgga
    16081 actcacttta cgcgagggga tgaaccggca agtccggcgg atgactgcgg cggttggcca
    16141 cccgaccttg cgactggtgc gggttgcaat tggttcgatc accttgggtg atctgcaacc
    16201 tggggaatgg cgggaactga ccaagcagga agtggccgat atgtttcatt cggcttagaa
    16261 tgcggtcgct ttgtgaacgg ggcacgtgag attcgtgatc cacctcgatt tgatttggca
    16321 cagtgctgag ccgaacgtgt cgcagagcca ggacaagtga gagtgactct cctacgttgt
    16381 tttcagaata ttctgacaag actgcgtgaa gatacgcatg ccgcctcctc tcttgaatgc
    16441 atctagatct ggatatggag cgtcaagctg aggtatatca agcgaggcga atagggtcga
    16501 actattgaat ggttcttcag acgagggaga ttgattatgt ggggacgcgc catcgtgact
    16561 aacaggtggt ccttgcttct gctgctgggc atcggcttct cacacgtgac gccggtcttc
    16621 ggcgccaatc cggactcggt cccggtcgcc gacatgcggc acattaaaaa atttgtcgct
    16681 gttgaggtgc agactcaagg aacagccgaa aagctcggta tcagtgcggc tgaattgacc
    16741 gacgtaacgc gcgtcacgtt gctgaacaag gtgccgggca tagtcctcga agcatcgagc
    16801 ggtccatctc ttgacgcgac tgagcgcctc aatcagctcg ggtttttcac ctgcgaagtc
    16861 tggacggtgg gtgaacaata catcgccgcc taccacgtgg attgcaatgc aggttcctat
    16921 acgccgcaaa agacccccgg gagcctgtgg aatcaggcga tcctcggcta cggaccgagg
    16981 gacgaagtct cggatgcggt gagaaaaggt gtgcgagcga tggttgaatt gttcgcgtct
    17041 acgtttgccg gtgtgcgagc tgatggaggg ggccgctaaa cgactctaca agtcatcagt
    17101 gttgttatct gccatacacc ccacaatcaa tcctcgatat ccttcgattt tcaattcggg
    17161 tcagaaactc ttcctagcag ctctgacggg tattgatcgc tctctcttgg tctgacggcg
    17221 ctccttcaac cacatgtgcc ggtaacgatt catctcggat gcaaagccgg acaccgaggt
    17281 tcgtatctgt tcatttccga ctgggcgcat cctgttgcgg ccctcggccg ggcagcgaga
    17341 attttaatgc gggagagtct gactcgtctc cccgcaacaa ctgacgcagt gaacactcct
    17401 ggggcgggtg gtgtgtgtga atatggtctc ttctgtctgc acatgtgagg cgtattcttt
    17461 tgcagcatgg catgttgaag tgagcttgga tcagggcttt ctcccagtct tctccgggcc
    17521 gatggagtct ggtcgtgatg atggcgctcg cgcgtgttct acgcagtaaa tcctacggtg
    17581 tgccgcgaag aagaaatatg aggcgacctc tttcctgcgc acgatctgcc taactcgctc
    17641 ttgatgtccg gtcagtcgtg atctgggaaa gaatttgttt taggctcgcg ctgggtttgg
    17701 cccggaggtt tggtaggaaa gcaagaattg gtaagtggtg atacgtattt attgatagtc
    17761 gaatgttagg aggggttctg attctagacg ctttcgacat ccgcgataat cgtatggagt
    17821 ccgcttgatc ccgctggttg agggcggatc aattcggcaa tctgtggctg ccctttgcta
    17881 tctacggctc gaacggcgac ctggtacttg cctcgtttgg gcgggtgcca ggtgtaattc
    17941 cagatcaccc acgaataggg cgacatcggc gtttcaattt cacaggaatc ccaggttcgc
    18001 gctgcgtcca gactgatttc tactctgctg atcgaatttg gtccgccgaa agcaatgccg
    18061 cgaaatcgtt gcactggacc gcgtagcgtc tggtaatgac ctggcgaatc gatgcgagaa
    18121 aatgtcttga tggttccatc atcggtccat cccttgcgct gccagtaccc cttgtaatcg
    18181 ccggcgtagg cttcgatttc gacaatccac ttcacatttt tgattccata cagccctggc
    18241 actagcaggc gaagcggaaa tccgtgctct ttcgacagtt tttcgccgtt cattaggaac
    18301 gccagcatga catcatcttg catggcacgg gtcagtggaa tgctatcgtc ataggcgtcg
    18361 gctcctcgaa acacgatgtc tcgcgtcgtg tcttcatcga cgccggcttc ctgcaatagt
    18421 tttttcaatg aaatgccgcg ccaccgtgca tttccgaggc tgtctcctcc gggcagggta
    18481 tcaatgcaca tgagcgtgga aatttgctcg aagttctcgc ggtttaataa ctcacgccac
    18541 cctagggata acggattttt tacttcgcct ttcaccgaca ggcgccattc atcctgtcgg
    18601 aggtcgcgag acacgttaaa cggggagtcg gagtagttca cgacatagaa tttcttattt
    18661 tccgtgaagt agttggtctc tcgagggggc atggcgaaca tgcgtccgaa aaaagatcca
    18721 actccgtcac agccacccgt gaggccggcc gcagccgcaa ttccagtgat ctttaggagg
    18781 cttcgccgct ttatggtcaa ccaattttcc ataagaaata ctctgcgata ttaaaaagat
    18841 cttttcaagg cttgactcca gaaatgcaga ttggtataag agtgcacgtt tgatccagcc
    18901 tagtggccga tgcggttgta agacctgcga cggattctca ggaaccccag atcaaaaaaa
    18961 ataaatcctg accctcttga caaggtcagg cgcacatagt aaagtgcgcg gctcgcgtgg
    19021 ggaacgaaaa acgttccgaa gcgtgaaacg gttctttgac aactgaatag agcgagaaat
    19081 gagtaaggta aggtgtattg aagaggtggc cctcgggtcc aattcaagta gaacctttat
    19141 gagagtttga tcctggctca gaacgaacgc tggcggcgcg cctaatacat gcaagtcgag
    19201 cgagaaggtg tagcaataca cttgtaaagc ggcgaacggg tgaggaatac atgggtaatc
    19261 taccatcgag tggggaataa ccaaccgaaa ggttggctaa taccgcgtac gcctccgagt
    19321 cttcgggttc ggagggaaag ctgcactgtg agtgtagcgc tctttgatga gctcatgtcc
    19381 tatcagcttg ttggtagggt aacggcctac caaggctttg acgggtagct ggtctgagag
    19441 gacgatcagc cacactggca ctgcgacacg ggccagactc ctacgggagg cagcagtaag
    19501 gaatattgcg caatgggcga aagcctgacg cagcgacgcc gcgtggggga tgaaggtctt
    19561 cggattgtaa acccctttcg ggagggaaga tggagcgagc aatcgttcgg acggtacctc
    19621 cagaagcagc cacggccaac ttcgtgccag cagccgcggt aatacgaagg tggcaagcgt
    19681 tgttcggatt cactgggcgt acagggtgtg taggcggttt ggtaagcctt ctgttaaagc
    19741 ttcgggccca acccggaaag cgcagagggt actgccaggc tagagggtgg gagaggagcg
    19801 cggaattccc ggtgtagcgg tgaaatgcgt agagatcggg aggaaggccg gtggcgaagg
    19861 cggcgctctg gaacatacct gacgctgaga cacgaaagcg tggggagcaa acaggattag
    19921 ataccctggt agtccacgcc ctaaactatg gatactaagt gtcggcgggt taccgccggt
    19981 gccgcagcta acgcattaag tatcccgcct gggaagtacg gccgcaaggt tgaaactcaa
    20041 aggaattgac gggggcccgc acaagcggtg gagcatgtgg tttaattcga cgcaacgcga
    20101 agaaccttac ccaggttgga catgcacgta gtagaagggt gaaagcctaa cgaggtagca
    20161 ataccagcgt gctcaggtgc tgcatggctg tcgtcagctc gtgccgtgag gtgttgggtt
    20221 aagtcccgca acgagcgcaa cccctgcttt cagttgctac cgggtcatgc cgagcactct
    20281 gaaaggactg cccaggataa cggggaggaa ggtggggatg acgtcaagtc agcatggcct
    20341 ttatgcctgg ggccacacac gtgctacaat ggccggtaca aagcgctgca aacctgtgag
    20401 ggggagccaa tcgcaaaaaa ccggcctcag ttcagattga ggtctgcaac tcgacctcat
    20461 gaaggcggaa tcgctagtaa tcgcggatca gcacgccgcg gtgaatacgt tcccgggcct
//
LOCUS       DAOQPD010000069        20474 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1273_length_20474_cov_21.971595, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000069 DAOQPD010000000
VERSION     DAOQPD010000069.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 20474)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 20474)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20474
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1273_length_20474_cov_21.971595"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..443
                     /locus_tag="PK063_14290"
     CDS             <1..443
                     /locus_tag="PK063_14290"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98268.1"
                     /translation="SGTLKAFNVYILDHHTFTFFQRSRGMKLVIGSVATLAGVLFLCS
                     MASANPALLPKHEGYPMKNDGSPVTGQPTANDPGQKDARGESFLLKSAESTKHAEQKL
                     TKTDNARITEGQGAGRLPNVQGPQIKIEPPVTSATKITGERKID"
     gene            complement(501..1076)
                     /locus_tag="PK063_14295"
     CDS             complement(501..1076)
                     /locus_tag="PK063_14295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HMZ98269.1"
                     /translation="MILPREYFDRPTLEVARALVGKYLVRDQGNRLLAGRIIEVEAYI
                     GAEDKACHASKGRTARTDVLFGPPGHAYVYLCYGMYEMLNVVTEQEGFPAAILLRAVE
                     CEGKLIDGPGRLTRAFDIDRRLNRCDLTLGQSLWFEDRGETLTPGLLNAHPRIGVDYA
                     GEWAHKPWRFRLTTETSRPRRLNAKRSLTRK"
     gene            complement(1455..3500)
                     /locus_tag="PK063_14300"
     CDS             complement(1455..3500)
                     /locus_tag="PK063_14300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor plug domain-containing
                     protein"
                     /protein_id="HMZ98270.1"
                     /translation="MTGALRYVVLWLALILWAAPLHAHDPDAVDLELPEVEVSADRPV
                     AASSQQFIPDKEYLMQPQGRPAQVLRLIPGFIAVEHSGGAGKADQYFLRGFDADHGTD
                     VAFFTDGMPINLRSHAHGQGYTDLNFIIPETIEGVDVYKGAYLPEYGDFATAGAVNFR
                     TRDMVKEGVVQSAGGQFNTQRHLLMFSPTKDAVRTLFAAEGYYTDGPFQNDNRYFRGN
                     LLGKATMNPLGRDELVITGTFQKSQWNGSGEIPLRAVHDGSLDRFGSIDPSEGGKTLR
                     STGRMNYHYDMPSGGRFFANAYAQYYRFDLFTNFTFFLNDPVNGDGFQQSDRRVVYGG
                     DVGYRHSGHLFDMDGAATVGVQARIDDIHARLAPQVKRAPLGSTADSTIFEASYAPFL
                     KLELQPTPWLRLAGGVRTEVFTFDVRNRCANCAEQPFGNTSTGLVLPKMNVILGPWFE
                     TEFFANYGEGYHSNDARSIVARAASPLAKARNYEVGVRSKPWGPDGVELIGTLWALDL
                     KQELVFVGDAGTTEIRGASRRRGLEVAARGQVWGPLYFNGSVTWTKAEFTNGDAIPLA
                     PEVTAYGALLLRWPEGLTSQLQATYLGVRPLVEDRSAKAPSWTTFDLSERYQLPVKLP
                     HGRLEAFLFVQNLFNTKWEQATFFFDSRLRNEAAGVADTHFVPGSPRFVMAGLAWYF"
     gene            complement(3508..3924)
                     /gene="nikR"
                     /locus_tag="PK063_14305"
     CDS             complement(3508..3924)
                     /gene="nikR"
                     /locus_tag="PK063_14305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0010045 - response to nickel cation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-responsive transcriptional regulator
                     NikR"
                     /protein_id="HMZ98271.1"
                     /translation="MDALARFGVSLDRHLLVDFDRLIERRKYTNRSEAIRDLIRDSLV
                     GQEWDENKDTVATITFVYDHHVPDLARKLTHIQHEFEGHIMAGMHVHLDHDHCLEVLV
                     ARGKGSAIRNVADALLSVKGVKHGKLTMTTTGKGLR"
     gene            complement(3984..4859)
                     /locus_tag="PK063_14310"
     CDS             complement(3984..4859)
                     /locus_tag="PK063_14310"
                     /inference="COORDINATES: protein motif:HMM:NF024258.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HMZ98272.1"
                     /translation="MRVRRWNARSVWYLLAGLLVALAGWGFWWEPASLSTREYDLVLP
                     GWPAAAGDLRIAVLADLHTGSPHNDLEKLQEVVASTNGTHPDLILLAGDFVIQGVVGG
                     RFVEPEASARVLRSLQATLGVYAVLGNHDWWLDGPRVRKALEAEGIPVLEDRAIPLVF
                     NRMPFWLAGVGDFWEAAHDVRRALTGVDEASPVIVVTHNPDVFPEIPARVTLTIAGHT
                     HGGQVAVPGLGRPVVPSQFGERYAIGHIVEQGRHLFVSTGIGTSILPVRFRVPPEISI
                     VTLRSAAPLSQPPRD"
     gene            complement(5041..6114)
                     /locus_tag="PK063_14315"
     CDS             complement(5041..6114)
                     /locus_tag="PK063_14315"
                     /inference="COORDINATES: protein motif:HMM:NF014069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ98273.1"
                     /translation="MQDVDLSTIKLLLVDDEAHCTKLMEAFLRQAGFSRITMTNDSRQ
                     ALELFQQVEPDLVALDMRMPHMDGFDVMRQLRQVIPADDYVPILIVTGELDAPTKHKA
                     LTEGANDFINKPVDATEVVLRIKNQLQTRRLHGQLRMHNEHLEAQVRLRTKVVEQTQL
                     DLLNRLVMASEYRYDPKGAHAWRVGRLAMLLSEMKGLPLEQTDMIKKTAPLHDVGKIG
                     LLDSIVMKEGSYTAIEWEAMKTHTKIGSKLLADSRSPLLMMAREIALTHHERWDGTGY
                     HRLKETQTPLPGRIVALVDAFDVMTHPRSYKGQLNLVEARAEIERHAGTQFDPELSAL
                     FLKLIDREGESLLADSTAVQLFA"
     gene            complement(6168..8921)
                     /locus_tag="PK063_14320"
     CDS             complement(6168..8921)
                     /locus_tag="PK063_14320"
                     /inference="COORDINATES: protein motif:HMM:NF013736.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ98274.1"
                     /translation="MQIEYSFLRTRLGRRVFVLFILCALLPVGVLSVVTIPQVTKYLR
                     TQAEEHMRQQSRAMGMAVYQRLLLLEEELLAITARQQVGASGRSEEWPSRPLSSRSGF
                     IGMASVSEADGTAVFGGGQRSRAFSSAERAILRQNKTLLTVEPAGVDRPRFFLSTMSE
                     QDGRVVVAEIKHDFLWDVGDSLAPPPDTSLCVFAQAGQTLLCTDAASVALSEQWLAQG
                     KASSGSFTWRDGDDEKLARAWGIPLRSRFSTDSWVVVLSKPMSVVLDQASDLRRQVRL
                     AIIAAVFASALLGVVQIRKFMGPLEQLGEGTRRIAARNFSTPVQVRSGDEFELLASSF
                     NAMAGRLNQQFTQLATIHEIDRSVLSVLDPSRIVDTVLTRVREVSPCDGIAMLLMDSS
                     DPARGWLYVRSGAKNKPTTMTGVSVGEEERRMLASHEGGTALIGVDGAAAFATLCRPG
                     VTALMVLPLFRSRDLLGAIAMSYRQAPEMDSEHKTQLRQLADQVAVALSNASDLAERK
                     RAEASLRESHTRLEQAMTDLQTAQQQMVQQERLRALGQMASGIAHDFNNTLSPIMGFS
                     ELLLIAPQMSADPAQLKEYLQTINMAAKDAAKVVSRLREFYRPRLDADLAGIVDLNRL
                     VEQSVKLSQPKWKDQALANGVAIEIKTELASVPPVAGHESELREVLTNLVFNAVDAMP
                     KSGSITLRTKADGDHVRLEVSDTGTGMTEEVRQRCLEPFFSTKGEKGSGLGLAMVYGI
                     IKRLRGTIEITSAVGVGTTFSIRLPIQSEQEAGTKQEGNSLAGVRLQILVVDDDPLVG
                     RVTGEYLRVAGHQVEVVTSAAEAVKRFNPERVHLVVTDHGMPNMTGRQLAEVIKQVSP
                     DTPVVLLTGGDEIEVTETASQAVDAELSKPLTMAALQRTLSTLTFPGSLPAESRKEIG
                     DAA"
     gene            complement(8937..9701)
                     /locus_tag="PK063_14325"
     CDS             complement(8937..9701)
                     /locus_tag="PK063_14325"
                     /inference="COORDINATES: protein motif:HMM:TIGR02532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HMZ98275.1"
                     /translation="MPHIPFDRRQQGFTIIELAIVMVIVGALAGLAVPMYVGYLDKAR
                     LARCIAEIRYISRAVDSYNAAYDVYPNTLAEAGAGEIVDPWGNPYEYLNIAALSLPGN
                     GGGNGNAGGNGGGGGSGGNGSSGGGNGNTPGGSGGGGTGSSSGGTGGTNATTPPSNNG
                     NGGGGGNHGAWDWLLPVEAYAAGNANGNGNGNGSGNASKGKPRKDRFLHPINSDYDLY
                     SMGKDGESVEPLTAKKSHDDVIRANDGSFVGLAVEF"
     gene            complement(9913..10548)
                     /locus_tag="PK063_14330"
     CDS             complement(9913..10548)
                     /locus_tag="PK063_14330"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_component: GO:0098561 - methyl accepting chemotaxis
                     protein complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HMZ98276.1"
                     /translation="MSRPRFRRHFLWDTVQPRFVGLSLLYVVVVIAAVSGALFLPLML
                     QLDHLPLSSVEAQRVADQFELLHSRFWPAVGVVSLLLIVHGVFFTHRIAGPLYRFRRI
                     FQSVANGDLTVRTSIRKSDYLHAEAQCLGEMVSALREKIGRIEAHHADMAPQLERLKA
                     AAARGALREVEQEADRLRATVEQLAQAMEPFQTTSEPVEPRPTPLPTAAGF"
     gene            complement(10545..10919)
                     /locus_tag="PK063_14335"
     CDS             complement(10545..10919)
                     /locus_tag="PK063_14335"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98277.1"
                     /translation="MWSIRAVSCLLVLWWCAACAPEPDQAPSYLIGVWETTTDGYVDQ
                     HMFIDQTRIGFGTSALAADGYMITKVDEGRDGARTLFVVSYQDAEQAKYQLSFYYDPA
                     GGGRITFKNQDHLVWTKRAATT"
     gene            complement(11096..12529)
                     /locus_tag="PK063_14340"
     CDS             complement(11096..12529)
                     /locus_tag="PK063_14340"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: protein motif:HMM:TIGR02037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Do family serine endopeptidase"
                     /protein_id="HMZ98278.1"
                     /translation="MSVRRSQPGLVALGIVGALLGCWPEGPASAADMLAPRFSKVSTN
                     GDLQAQVRATAAKVLPAVVSIASTVMVHDQGFSDEGLPFGMFKDVPPRRQYGQGSGVI
                     VSSDGYIITNNHVVADAVDVEVILADRRQFKGRVVATDPKTDVAVVKINASGLPTAAW
                     GDSSALAVGDFVLAIGNPLGLSRTVTFGIVSAVGRADVGVADVEDFIQTDAPINPGNS
                     GGALVNTNGELVGINTAIASPTGGSVGVGFAIPSNMARTAMQSLIKTGRVVRGFLGAS
                     TQDVTPLLAKIFHLPDVKGSIITDLQAKGSAERAGLKRGDVVVRFDGRDVMDSGHLRN
                     LMAAAAIGSKHRVELLRDARLMQAELTVQEAPRERQRKTQSAETAGPTAHPLSGVIVD
                     EITPALARQMDLPSNTGLVVTDIEDGSLAEVSGLQPGDLLLELNRQPIPNFSTFQRLA
                     EPLRSTDLALLLINRQGSLLYIPIQTE"
     gene            complement(12597..15494)
                     /locus_tag="PK063_14345"
     CDS             complement(12597..15494)
                     /locus_tag="PK063_14345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HMZ98279.1"
                     /translation="MARDPVCGMTVEPATAAGYAEYEGETYHFCSPSCRDRFRAAPAH
                     YVKKAAPAGAAVQPSSRRSLPMMQAMPAQEATTGGERDPVCGMMVEPATAAGSHTHEQ
                     KTYYFCCQGCLEKFRADPGRYLAPVAAPASTSLRQFGGKALPMLGAASSPGPSAAAVI
                     DPVCGMTVDPATAAGSFAYQDTTYFFCCQGCLTKFRADPARYLSPGSVKDAMPATPVP
                     PGTKYVCPMCPEVLEEKPVPCPKCGMALEPDSVQPLPTKTEYVCPMHPEVVQAEPGAC
                     PKCGMALEPRTVTVAEELNPELVDMARRFWVALGPAAIVFLLAMSHMLPGHPIQHLLS
                     DTQSAWVQFVLSTPVVLWAGWPFFQRGWASIVHRSPNMFTLIAIGTGTAYLYSVIATL
                     FPFSIPQSFHLESGAVPVYFEAAAVITVLVLLGQVLELRARSRTTGAIRALLGLAPKT
                     ARRLFDDGREEDVPLEQVQVGQRLRVRPGERVPVDGVILEGATSIDESMITGESIPVE
                     KFAGERVTGGTINGSGGVVMRADRVGADTLLSHIVQMVAEAQRSRAPIQRTADVVAGY
                     FVPVVVSVALVTGILWAWLGPEPRLAHALLNAVAVLIIACPCALGLATPMSIMVGTGR
                     GASAGVLFKKAESLETIEKVTTLVFDKTGTLTEGKPKLRVVSAMPPWSETDLLRLAAS
                     VERGSEHPVANAIVGGAEARGLNLEPAAGFTSKAGKGVMATVGTKRVAVGTIDWLRDL
                     KVGDEAALAALDANAELMRQTGQTVMLVAVDGQAIGLLGVADPIKSSTPEALRLLRQE
                     GIRLVMVTGDHAVTAQAVAKELGLDEVRAGVKPEDKSRIVQELQRQGQVVAMAGDGIN
                     DAPALAQADVGIAMGTGTDVAMENAGVTLVKGDLRGIVRAYRLSKATMRNIRQNLFFA
                     FVYNSIGVPIAAGLFYPVFGLLLSPMIASAAMTGSSLSVISNALRLRQTDL"
     gene            complement(15603..16247)
                     /locus_tag="PK063_14350"
     CDS             complement(15603..16247)
                     /locus_tag="PK063_14350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HMZ98280.1"
                     /translation="MVMRRVWHGGLFVGVMVMALVGLAGTAQAAKPELKGNFQVLSEE
                     KSTHKPGKVQLVEFADFYCPHCHRFDGEGLMILEKEFGNKVEAVMVGYPVIPGKLPTA
                     FDMYEQAKSMGKGNEMKRALFRTIHKDKVGIIDKAIREVLIREVGLNPAAFEEGLASA
                     KPAKAFEDGRKWGDRIKIQQTPTVLLDGNIKVEQIDPENLKLIIQSILDGDSKK"
     gene            16344..16895
                     /locus_tag="PK063_14355"
     CDS             16344..16895
                     /locus_tag="PK063_14355"
                     /inference="COORDINATES: protein motif:HMM:TIGR00752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Slp family lipoprotein"
                     /protein_id="HMZ98281.1"
                     /translation="MRGKLLQGLGILCMAAILAACATSADQREAEDGASQTPQFSQIK
                     AAPESFKGQTVVLGGQVLSARRMKDGTRLEVLQLPLNDAQQPSLDLTKSQGRFIAIRR
                     EFLDPATVPQGTFVTITGQMTGSVTQPLDETDYAYPVLEITTFRTWIPSQDLNLPRYR
                     PYPYYSPFWHPYWGPYGRFPYYW"
     gene            complement(17051..17530)
                     /locus_tag="PK063_14360"
     CDS             complement(17051..17530)
                     /locus_tag="PK063_14360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98282.1"
                     /translation="MLSRSAVVLFGALSLLSSATGAWALQAGGVEVGDLETGSVVGQP
                     FKELEVDAQLFAVEVGGLKAWYPPTTIIDFKVRPGRPVLLKVTNNTSSDRGFQMTDPV
                     NAASPFVLKAEVVLKPGETKYIGVPTSDLFNATQGNTLTYRDQLNPKQPGGQLIMIK"
     gene            complement(17549..17893)
                     /locus_tag="PK063_14365"
     CDS             complement(17549..17893)
                     /locus_tag="PK063_14365"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98283.1"
                     /translation="MRCVCIVLIQLLVVAGGTAGWGADDSLEHLLRAQAFNKEFEGFD
                     FYYVNIEADHPQPDGSHEVLAIASGKFSDSTKRMKVLFLIVDGLIVGGQVLEGTGLPP
                     CLAPEHRSSSSL"
     gene            complement(18135..18437)
                     /gene="smbP"
                     /locus_tag="PK063_14370"
     CDS             complement(18135..18437)
                     /gene="smbP"
                     /locus_tag="PK063_14370"
                     /inference="COORDINATES: protein motif:HMM:NF028095.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="small metal-binding protein SmbP"
                     /protein_id="HMZ98284.1"
                     /translation="MTGLRAGVVVASLCALVAVAPANMALADGGGHVKETIKHAKEGV
                     EHEKEAIKHLEEAVKGSNDPHAKEALEHAKEAVKHAEESLAHAEQASGKKGKGKGN"
     gene            complement(18647..19171)
                     /locus_tag="PK063_14375"
     CDS             complement(18647..19171)
                     /locus_tag="PK063_14375"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98285.1"
                     /translation="MPVSDAVASPQRTTVAGKPYDQTGLNVAVVRLLALALDISGGWS
                     PAPPAAGLMIPFGYRDWPHLTSLVQSSGGAQELRFYVCPKGLLTADDRSFPVGTVFVV
                     ESEPCPVGIGAQESRPAVFVMEKCAGMTRDEVGTAQSELWIYASWDSGGQSARADPGR
                     CGICRLPWLTPASA"
     gene            complement(19203..>20474)
                     /locus_tag="PK063_14380"
     CDS             complement(19203..>20474)
                     /locus_tag="PK063_14380"
                     /inference="COORDINATES: protein motif:HMM:NF037660.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ98286.1"
                     /translation="GLPLHPGPSGAGKVKTGARNGNDGMSPESIEGVEDSTIMSDRMN
                     RRWYRMGFVSLVALIVLCAATGSGATEPDGWMQRFEEGVKAREAAHYGEAEPLLAQAL
                     REAAQSRADDARVALAANQLGLLYHDQGRLSEAEALYLRALGTWEAQLGPEHEDVAAA
                     LNNLAEIAHAKGEWAAAEPLYERVLKIERQTLGPAHPDVAISLNNLAELYRKQGRETA
                     AESTYRLALTLMEQAHGPDHVELGPVLNNLAALYKGRGMYAWAEPLYERALKVRRLRF
                     GNDHPAVVMSLNNLACLYQAEGLYASAQRHFDEALPLAERLSGPQSALAGTIIGNMAF
                     LADQQGLMAQAQLWYQRALVIQQQQLGVHHPTVGLLVERYAVVLNSIGQSVEAGLYAA
                     RAASIRARSQPGAVKQGAVSYLGATVGEASR"
BASE COUNT         4200 a         6666 c         5611 g         3997 t
ORIGIN      
        1 attccggcac tcttaaggct tttaacgtct atatactcga ccaccatact ttcacattct
       61 ttcaaaggag taggggtatg aaactcgtga tcggcagcgt cgcgaccctt gcaggtgtat
      121 tgtttctgtg ttcgatggcc tccgcaaacc cggcgctgtt gccgaagcac gaaggttatc
      181 cgatgaagaa cgacggcagc cccgtcacgg gacagccgac agccaatgat cccggccaaa
      241 aggatgctcg cggcgaatcc ttcttgctga agtccgccga gtccaccaag catgccgagc
      301 agaagctgac caagacggac aatgcgcgta tcaccgaagg ccagggcgca ggccgtttgc
      361 cgaacgtgca gggtccgcag atcaagattg agccacctgt gacctcggcg accaagatca
      421 ccggcgagcg aaagatcgac taattctcga ttactagaat ccgtgctatg aaggggaagc
      481 cgtacatcgg cttccccttt ttattttctg gtgagggacc gtttggcatt gagacggcgg
      541 ggcctggatg tctccgtcgt caggcgaaac cgccagggtt tatgagccca ctccccggcg
      601 taatccaccc cgatacgcgg atgggcattg agcaagcctg gcgtaagcgt ctcgccacga
      661 tcctcaaacc aaagtgactg gccaagtgtc aggtcgcagc gattcaatcg gcgatcgata
      721 tcgaaggccc gggttaaccg gcccggtcca tcgattaatt ttccttcgca ttccacggca
      781 cggaggagaa ttgccgccgg aaatccctcc tgctccgtga ccacattcag catttcatac
      841 atgccgtagc agaggtagac ataggcatgg cccggtggac cgaacaacac atccgtacgt
      901 gccgtccgcc ccttcgaagc atgacaggcc ttatcctccg cgccgatgta ggcctccact
      961 tcgatgatcc gtccggcaag cagcctgttt ccctgatcgc gcacgagata tttccccacc
     1021 agcgcacggg ccacctcgag tgtgggacga tcgaaatact cacgaggaag aatcatggcc
     1081 gctcctaaaa acatccggac aagcccgaat cgtaaatgcc gatgccccgc actttcaatc
     1141 gctgacatca ccggaacttc tttgttcagt tcccctcgcg accgctcaaa ccgtcatcca
     1201 gcaaagcctc agctgacgca gcagcggagt cccgatcctt gagaccgctc aaaaatggct
     1261 tcccaacaag gccgcaggtg agaaaatacc gcaggcgtac ccgcattctg ctggtgatgt
     1321 gccctcagac aggccgctca aaatgtccgt tcagctaggc cgcagccgag ggtagcgccg
     1381 gaggcgtagc ccgtggctac gttgaggacg gtaccgaggc gagaacaacg ctggcgggca
     1441 ttttcagcag cctgtcagaa gtaccaggcg agaccagcca tcacaaaccg tggactcccc
     1501 ggcacaaagt gcgtgtccgc aacgccggcc gcttcgttac gtagacggga gtcaaaaaag
     1561 aacgtggcct gctcccattt cgtgttgaag agattctgca caaagagaaa tgcctccaac
     1621 cggccgtgcg gcagtttcac cgggagttga tagcgctccg acaaatcgaa cgtagtccag
     1681 gacggcgcct tcgcgctgcg gtcttcaacc agcggtcgaa cgcccagata cgtcgcttgc
     1741 agctgggatg tcagcccttc cggccaccgc aacagcaacg cgccataggc ggtcacttcc
     1801 ggcgccaacg gaatcgcgtc tccgtttgtg aattccgcct tggtccaggt cacgctaccg
     1861 ttaaagtaga gcggccccca gacctgaccc cgtgccgcga cttccaggcc gcgccgtcgc
     1921 gaagccccac ggatctccgt cgtccctgca tctcccacaa agacgagttc ctgtttcagg
     1981 tccagcgccc acaaggttcc gatcaattca actccgtcag gcccccacgg cttcgaacga
     2041 acaccgactt cgtaatttct cgctttcgcc aatggtgagg cagcccgggc cacgattgag
     2101 cgggcgtcgt tactgtgata cccctcgccg tagttcgcaa agaattccgt ctcgaaccag
     2161 ggccccagaa tcacgttcat cttcggcagc acgagccccg tactcgtatt gccaaacggc
     2221 tgttccgcac agtttgcaca acggtttcgc acgtcgaacg tgaagacttc ggtgcggaca
     2281 cctccggcca gtcgcaacca aggcgtaggc tgcagctcca attttaagaa gggcgcgtag
     2341 gaggcttcga aaatcgtgct gtccgcggtg gatcccagcg gcgcccgttt cacttgcggt
     2401 gcaaggcgcg catggatgtc gtctatccgt gcctgtacac ccacggtcgc ggctccgtcc
     2461 atgtcgaaca gatgtccact gtgacgatac cccacatcac cgccgtagac cacgcgccgg
     2521 tctgattgct gaaagccgtc gccgttgacc gggtcgttga gaaaaaacgt gaaattcgta
     2581 aacagatcga accgataata ctgcgcatag gcgttggcaa agaaccgccc gcctgatggc
     2641 atgtcgtaat ggtaattcat gcgacccgtg ctacggagcg tcttcccgcc ttcgctcgga
     2701 tcgatcgatc caaagcgatc caacgagcca tcatgcaccg cgcgaagcgg aatctcgccg
     2761 gacccgttcc actgcgactt ttgaaacgtg ccggttatga ccaattcgtc ccgacccagc
     2821 gggttcatcg tggccttgcc caacaggttg ccgcggaaat accggttgtc attctggaac
     2881 ggcccgtcgg tgtaatagcc ttccgctgcg aacagggttc gtaccgcatc tttggtcggc
     2941 gagaacatca ggagatggcg ctgggtgttg aactgtccac cggccgactg gacgacgcct
     3001 tccttcacca tgtcacgcgt gcggaaattc accgcgccgg ctgtagcgaa atctccatac
     3061 tcgggcagat aggccccttt gtagacatcg acgccttcaa tggtttccgg aatgatgaag
     3121 ttcagatcgg tgtagccctg tccatgggca tgacttcgca aattgatcgg catgccgtca
     3181 gtgaagaatg cgacatcggt gccatggtcc gcatcaaacc cgcgcaggaa gtactgatcg
     3241 gcctttccgg ccccacccga atgttcgacc gcaatgaatc cggggatgag ccgcaagacc
     3301 tgggccggac ggccctgcgg ctgcatgaga tattccttat cgggaatgaa ctgttgagag
     3361 gatgctgcca ccggccgatc agcagacact tcgacttccg gcagctcgag gtccacggca
     3421 tccggatcat gggcgtgaag cggcgcagcc cacaggatca gagcgagcca cagcacgacg
     3481 taacgcagcg caccagtcac cggcggctca ccgtagccct ttgccggtgg tcgtcatggt
     3541 caacttgcca tgcttcacgc ccttgacgct gagcaacgcg tcggccacgt tgcggatggc
     3601 cgaccctttg ccacgcgcca ccaacacctc gaggcaatga tcatggtcca aatgcacatg
     3661 catcccggcc atgatgtgcc cctcaaactc gtgctgaatg tgggtcagct tccgggcgag
     3721 gtccggcaca tgatggtcgt acacaaacgt gatcgtcgcg accgtatcct tgttctcatc
     3781 ccactcctga ccgaccagac tgtctcgaat gagatcgcga atcgcctcag agcgattcgt
     3841 gtacttccgc cgttcgatca ggcgatcgaa atcgacgagc agatgacgat cgagtgacac
     3901 gccgaatcgc gcgagtgcgt ccatgccgcc tccttcaacg gtgctacaaa tatttttttt
     3961 gtaacactgc gatgaaagac gcgtcaatca cgaggaggct gactgagagg ggctgcggac
     4021 cgaagggtga cgatcgatat ttccggcggc acgcgaaagc gaaccggcag gatactggtg
     4081 ccgatgcccg tgctcacaaa caaatgccgc ccctgttcga cgatatgccc aatggcatac
     4141 cgctctccga attgagacgg cacgacaggc cgtcctaatc ccggcactgc cacctgcccg
     4201 ccatgtgtat ggccggcaat cgtcaaggtc acacgggccg gaatctcggg aaagacatcc
     4261 gggttgtgcg tcacaacgat caccggactt gcctcgtcca cgccggtaag cgcgcggcga
     4321 acatcatgcg ccgcttccca aaaatcaccg acaccggcta accagaacgg catccggttg
     4381 aacacgagcg ggatggcacg gtcctccagc accggaatgc cttcggcttc aagcgctttc
     4441 cgcacacgcg gaccatcaag ccaccaatcg tggttgccta acaccgcgta gactcccagc
     4501 gtcgcctgca gcgagcgaag gacccgggcg ctcgcttccg gttcaacaaa acgtccgccc
     4561 accacaccct ggatcacaaa atcccccgcc aacaggatca ggtccggatg cgtgccattg
     4621 gtggatgcca ccacctcctg caacttttcg agatcgttat gaggtgagcc ggtatgcaga
     4681 tccgccaaaa ccgctatccg caggtcaccc gcagcggcag gccatccggg taagacgaga
     4741 tcatattctc gggtagacag cgatgcaggc tcccaccaga agccccagcc agccaaggca
     4801 accaacagcc cggcgaggag ataccaaacg ctgcgagcgt tccatcgcct gacgcgcatg
     4861 gccattaaga ccgcgacctc ataaactggt accaatcggg tgatgtctct gccgaccgaa
     4921 cgcagtcagc gtcgaacatc gccatctcgt cgcagtctct tctcgcgaac aggcgatcat
     4981 gggatgacga tgctcgtgtc tgatcagaca gcctgatctg ccggtgggga aacgagggga
     5041 ctatgcaaac aactgcacgg ccgtcgagtc ggccaggaga ctctcgcctt cacgatcgat
     5101 gagcttgaga aagagggcgc tcaactccgg atcaaactgc gtccctgcat gtcgctcgat
     5161 ctcggccctg gcctccacga gattcagctg gcctttgtac gaacgtggat gggtcatgac
     5221 atcaaatgca tccacgagcg ccacgatccg accgggcaag ggagtttgcg tctccttcag
     5281 gcgatgatat ccggtgccgt cccatcgttc atgatgcgtc aacgcaattt ctcgtgccat
     5341 catcaagagc ggagaccggc tatcggccaa gagtttcgac ccgatcttgg tgtgcgtctt
     5401 cattgcttcc cactcaatcg cagtatagga accttctttc atgacgatgg aatccagcag
     5461 accgatcttc cccacatcat gaagcggagc ggttttcttg atcatgtcgg tctgttcaag
     5521 cggcaatccc ttcatctccg acagcagcat ggccagacgg cccacgcgcc aggcatgggc
     5581 ccccttggga tcatagcggt attcggaggc catgaccaag cgattgagca gatccagctg
     5641 cgtctgttcc acgactttgg tgcgcagccg gacctgggct tcaaggtgct cgttgtgcat
     5701 ccgcaactgc ccgtgaagac gtctggtctg cagctggttc ttgatccgta acaccacttc
     5761 ggtggcgtcg acgggtttat tgatgaaatc gttggcccct tcggtgagcg ccttgtgttt
     5821 cgtcggcgcg tccaactcac ccgtcacgat caaaatcggg acatagtcgt cggcaggaat
     5881 gacctgtctt aactgtcgca tcacgtcaaa cccatccatg tgcggcatgc gcatatcgag
     5941 ggcgacgaga tccggctcca cctgttggaa cagctccagc gcctgacgag agtcattggt
     6001 catcgtgatg cggctgaagc cggcctgccg gaggaaagcc tccatcagtt tggtgcaatg
     6061 ggcttcatca tcgaccaaca gcagtttgat ggtgctcaga tcaacgtctt gcatcgcgct
     6121 cacaccgctc ctctgtccgc agactcctac ggtcgagatt accaccgtca ggccgcatcg
     6181 ccaatttctt ttctgctctc cgcagggagc gaaccgggga acgtgagagt cgacaaggtc
     6241 cgctggagcg ccgccatggt caacggcttg ctcaactcgg catcgacggc ttgggaagcg
     6301 gtctccgtga cctcaatctc gtcgccgccc gtcagcagca ccaccggcgt gtccggcgac
     6361 acctgtttga tgacttcggc caactgtcgc ccggtcatgt tcggcatacc gtgatcggtc
     6421 acgaccaggt gcacccgctc ggggttgaac cgcttcaccg cttcggccgc actggtaacg
     6481 acctcgacct gatggccggc cacccgcaga tattcgccgg tcacacgacc caccagcgga
     6541 tcatcatcga cgacaagtat ctgcagccgc accccggcca ggctgttgcc ttcctgtttg
     6601 gtgcccgcct cctgctcgga ttgaatcggc aaacggatgc tgaaagtcgt ccccaccccg
     6661 acggcactgg tgatctcgat cgtcccgcgc agccgtttga tgatcccata caccattgcc
     6721 aacccgaggc cggacccctt ttcgcccttg gtggaaaaaa acggctccag acaacgctga
     6781 cggacctcct cggtcatgcc cgtgccggta tcgctgactt caagacgcac atggtcgcca
     6841 tccgccttcg tccgcagcgt gatcgacccg ctcttcggca tggcatccac ggcgttgaag
     6901 acgagattcg tcagcacttc ccgcaattcc gattcgtgtc cggccaccgg aggcaccgaa
     6961 gccaattccg ttttgatctc gatggccacg ccgttcgcca aggcctgatc cttccatttc
     7021 ggctggctga gcttcacact ctgttcgacg agtcgattga gatccacgat gccggccagg
     7081 tccgcatcga ggcggggccg ataaaattcg cgcagacggc tgacgacttt cgccgcatcc
     7141 ttggcggcca tattgatggt ctggagatat tccttgagtt gcgcgggatc ggccgacatc
     7201 tgcggcgcaa tcagcaacag ttcgctgaac cccataatgg gcgacagcgt gttattgaaa
     7261 tcatgcgcga tgccgctcgc catttggcct aaggcgcgaa gccgttcctg ctgcaccatt
     7321 tgctgctgtg cggtctgcag gtcggtcatg gcctgctcga gccgcgtatg gctttcacgc
     7381 agcgaggcct ctgcacgctt ccgctccgcc agatcagaag cattactcag cgccaccgcc
     7441 acctgatcgg ccaactgacg caattgcgtc ttgtgctcgg aatccatctc cggtgcctgg
     7501 cggtaactca tcgcgattgc acccagcaga tcgcgtgagc ggaacaaggg cagcaccatc
     7561 agagccgtca cgcccggtct acagagggtg gcaaacgcag cggctccatc caccccgatc
     7621 agcgcggtgc cgccttcgtg ggaggccagc atccggcgct cttcttcgcc cacagacacg
     7681 ccggtcatcg tcgtcggctt gttcttcgcc cccgatctga catagagcca gcctcgcgcc
     7741 ggatcggacg aatccatcag cagcatggcg atcccgtcgc aaggcgacac ctcacgcacc
     7801 cgggtcaata ccgtatccac aatgcgactg ggatcgagca ccgacagcac cgagcgatca
     7861 atctcatgga tcgtggccaa ctgggtgaac tgttgattca accgaccggc catcgcgttg
     7921 aacgacgagg ctagcaattc gaactcatcg ccgctccgca cctgcaccgg cgtcgaaaag
     7981 tttcgcgcag cgattcgcct ggtgccctcg cccagttgtt ccagcgggcc cataaacttc
     8041 cgaatctgaa ccacaccgag gagggctgag gcaaacaccg ccgcgatgat agccaggcgg
     8101 acctgacggc ggaggtcgct cgcctgatcc aacaccacac tcatgggttt actcagcacc
     8161 accacccagg aatccgtcga gaatcttgac ctgagcggga tgccccaggc ccgcgccagc
     8221 ttctcgtcat cgccatctcg ccatgtgaaa cttccggagc tggctttgcc ctgcgctagc
     8281 cactgctccg acagcgctac ggacgcagca tcggtgcaaa ggagcgtttg cccagcctgg
     8341 gcgaaaacac acagtgaagt gtcgggcggt ggcgcaagac tatcgcccac atcccataaa
     8401 aagtcgtgct tgatttccgc gaccaccact cggccatctt gctccgacat ggtggaaaga
     8461 aaaaaacgag gtcggtcaac accagcgggt tcgaccgtga ggagcgtctt gttctgacga
     8521 agtatcgcac gctccgcaga gctgaaagcg cgggaccgct gcccaccacc aaacaccgcc
     8581 gttccgtcgg cttccgagac agaggccatg ccgatgaatc ccgaacggct cgatagcggc
     8641 cgcgagggcc actcttcgga ccgcccggaa gcaccgacct gctgtcgtgc cgtgatcgca
     8701 agcaattcct cctccaatag cagcaaccgc tggtacacgg ccatgcccat ggccctgctt
     8761 tgctgccgca tgtgttcttc ggcctgcgtc ctgaggtatt tcgtcacttg agggatcgtg
     8821 acgacgctca acacgccaac ggggagtagt gcacagagga tgaacaggac aaagacgcgc
     8881 cggcccagac gagtgcggag gaaagaatat tcgatctgca caatagcttc gtctcgttaa
     8941 aactcaacgg ccagcccaac aaagctgccg tcattcgcgc ggatcacgtc gtcgtgactt
     9001 ttcttggctg tgagcggttc cacactctca ccatcttttc ccatgctata caggtcgtag
     9061 tcggagttga ttgggtgcag gaagcgatcc tttctcggtt tgcccttgct cgcattcccc
     9121 gatccgttgc cgttgccatt cccgtttgca tttccggctg cgtaggcctc gacggggagg
     9181 agccagtccc aggcaccgtg gtttccacca cccccgccat ttccattgtt actgggtggg
     9241 gtcgttgcgt ttgtgccccc ggttcctcca gaactactcc cagtacctcc tccaccgctt
     9301 ccgcccggag tatttccatt gcctccacca ctgctcccat ttcctcctga cccgccacct
     9361 ccaccgtttc cgccagcatt cccgttacca ccaccattcc ctggcaaact caaggcggca
     9421 atgttcagat actcgtaggg attcccccag gggtcgacga tctcgccggc tcctgcttcg
     9481 gccaatgtgt tgggatagac atcataggcg gcgttgtagg aatcaaccgc gcgggagatg
     9541 taacgaattt cggcaatgca gcgcgcgagc ctggctttat ccaagtaccc cacgtacatc
     9601 ggcacggcca acccggccag agcgccgaca atcaccatca caatggccag ttcgataatg
     9661 gtgaatccct gctggcgacg atcgaaggga atgtgaggca taacgatcct agaatgcaga
     9721 gcaaaaactc gcttattgcg caacacgcta cagctcactg ccgtgccgcc tcgctttggc
     9781 tgtcacccgc aggatgcgca aaaagtccgt ccagcaaggc cgcagcaaac gaagaggcga
     9841 atcgtactcg ccccgtacgg tgagcctctg agtgccgcga gaacgccgct ggcggacttt
     9901 ttccgcatcc tgctagaatc ctgcagcggt gggcaaaggc gtgggacgcg gctcaaccgg
     9961 ttcagaggtg gtctggaacg gctccatcgc ctgcgccagt tgttcgacag tggcgcgcaa
    10021 tcgatcagcc tcctgctcca cttcgcgtaa ggcaccacga gcggccgcgg ccttcagccg
    10081 ctccaactgc ggggccatat cggcatggtg cgcctcgatc cggccgatct tctcccgcaa
    10141 cgcactgacc atttctccca aacactgggc ttcggcatgc agatagtcgc tcttgcgaat
    10201 cgaggtgcgc acggtcagat ccccgttcgc cacggactgg aaaatccggc ggaagcgata
    10261 gagcgggccg gcgatgcggt gcgtgaaaaa tactccgtgg acgatcaaca ataacgacac
    10321 caccccgacg gccggccaga accggctgtg caacagctca aactgatcgg ccactcgctg
    10381 cgcctcaacc gaggacaggg gcaggtgatc cagttgcaac atgagcggaa gaaataacgc
    10441 gccggagacg gccgcgatga ccaccaccac gtagaggaga ctcaggccca caaacctcgg
    10501 ctggaccgtg tcccacaaaa aatgccgtct gaaacgtggc ctgctcatgt ggtcgccgcc
    10561 cttttggtcc aaaccaaatg atcctggttt ttaaacgtga tccgtccgcc tccggcggga
    10621 tcgtaataaa acgacaattg gtacttcgcc tgctcggcat cctgatagga cacgacgaag
    10681 agcgttctgg ccccatcgcg accttcgtcg accttcgtaa tcatgtagcc gtccgccgcg
    10741 agcgcgctgg tcccgaatcc gatccgggtt tggtcaatga acatatgttg atcgacatac
    10801 ccatcggtgg tggtttccca cacgccgatc agatacgacg gagcctgatc cggttcagga
    10861 gcacaagcgg cacaccacca cagcaccagc agacaactca ccgctctgat cgaccacaca
    10921 agtcacctct tcccatgggg tgtcggcgaa atcgactcga cacggaatca gtatgtcgca
    10981 gttgccggga aatacaattt ctttaaaagt tcctacacgc agggcggagg gtcagaaaaa
    11041 cagcgtcggg cagccggcag gtgccagcaa cgtgtgcggg agagtcggaa aagaactatt
    11101 cggtttggat cgggatgtag agcagactgc cctgcctgtt gatgagcagc agagcgaggt
    11161 ccgttgaacg aagcggctcg gcgagccgtt gaaaggtgct gaagttggga atgggctgtc
    11221 gattgagttc cagcagcaga tcacctggtt gcaggcccga tacttccgcc aggctgccgt
    11281 cttcgatatc cgtcaccacc aggccggtgt tggaagggag atccatctgg cgcgccagcg
    11341 cgggagtgat ttcatccacg atcacacctg aaagaggatg cgctgtggga ccagccgtct
    11401 cggcagactg cgtcttccgc tgccgttcgc gcggcgcctc ctgcacggtc aattcggctt
    11461 gcatcaagcg ggcatcccgc aggagttcga cccggtgttt gctgccgatg gcggcggccg
    11521 ccatcagatt gcgcagatgg ccgctatcca tgacatcacg cccgtcaaac cgcaccacca
    11581 cgtcgccgcg cttcaacccg gcacgttcgg cagagccctt ggcctgcaga tcggtaatga
    11641 tcgacccctt cacgtccggc aggtgaaaaa tcttcgccag caagggcgtc acatcctggg
    11701 tcgatgcgcc cagaaatcct cgcaccacac ggcctgtttt gatgagactc tgcatggcgg
    11761 tcctggccat gttgctggga atcgcaaagc ctacgccgac gctcccgccc gtaggactgg
    11821 cgatggcggt gttgatcccg accaactctc cattggtatt gaccaaggcg ccacccgaat
    11881 tgccgggatt gatcggcgcg tcggtctgaa tgaaatcttc cacatcggcg acacccacat
    11941 cggcccgtcc gactgcgctc acgatgccga aggtcaccgt gcggctcagg ccgagcgggt
    12001 ttccgatcgc cagaacaaaa tcaccgacag cgagcgcact ggaatcgccc caggctgcag
    12061 tgggaagccc gctcgcattg atttttacga cggccacatc cgtcttcgga tcggtcgcga
    12121 cgacgcgccc tttgaactgc cggcggtcgg ccaggatgac ttccacgtcc accgcatcgg
    12181 ccaccacgtg attgttcgtg atgatatacc cgtccgacga gacgatgacc ccggatccct
    12241 gcccgtattg gcggcgaggc ggcacatcct taaacatgcc gaacggcagg ccttcatcgc
    12301 tgaacccctg atcgtgcacc atgacggtgg acgcaatgct gaccacggca ggaagaacct
    12361 tggcggcggt agcccgcacc tgcgcctgca aatcgccgtt ggtgctcacc ttggagaaac
    12421 ggggcgcaag catatcagcc gctgaggcag gtccttccgg ccaacagccc agcagcgcgc
    12481 ctacgattcc cagagccacc aggcccggct gtgatcgacg taccgacatg gtgtgacaca
    12541 tcctcaagac ggcagggccc accctatcac gcacagggtt cacgcacacg cagaactcat
    12601 aaatcggtct gccgcaagcg tagcgcgttc gaaatgacgg acagcgaact ccctgtcatc
    12661 gcagcactgg caatcatcgg gctcagcaga agaccgaaca ccggatagaa gagcccggcc
    12721 gcgatgggca caccaatact attgtacaca aaggcgaaga agagattctg tcggatgttc
    12781 ctcatcgtgg ccttgctcaa gcgataggcc cggacgattc cccgcagatc acccttcacg
    12841 agcgtgactc cggcattttc catggcgaca tcggtgccgg ttcccatcgc gatcccgaca
    12901 tcggcctggg ccaaggcagg cgcatcgttg atgccatctc ccgccatcgc cacgacctga
    12961 ccttgccgct gcagctcctg cacgatccgg ctcttgtctt ccggtttgac gccggcccgc
    13021 acctcatcca gacccaattc cttcgccact gcctgtgctg taacggcatg gtctccggtg
    13081 accatgacca ggcgaatgcc ttcctgcctc aacaagcgca gcgcctcagg ggtggagctc
    13141 ttgatcgggt cggccacgcc cagcaatccg atcgcctggc catccaccgc caccagcatc
    13201 acagtctgtc cggtctgccg catcaattcg gcattggcat ccaacgcggc aagggctgct
    13261 tcgtcgccca ccttcaggtc ccgcaaccag tcgatagtcc ctacggcaac tcgcttcgtc
    13321 ccgacggtcg ccatgacgcc tttccccgcc ttcgaggtga acccggccgc cggctctaaa
    13381 ttcaaccctc gcgcttcggc cccgccgaca atcgcgttgg cgaccggatg ctcactaccc
    13441 cgctcaaccg acgcggccaa ccgcaacaga tcggtttccg accagggtgg catcgcactg
    13501 actacccgca actttggctt gccttccgtc aacgtcccgg tcttgtcgaa caccagcgtg
    13561 gtgacctttt cgatcgtctc caacgactca gcctttttga acaagactcc ggccgacgca
    13621 ccccgccccg tccccaccat gatagacatg ggcgtggcca gccccagcgc gcaggggcag
    13681 gcaatgatta acactgccac ggcattcaac agggcatggg ctagacgagg ctccggtccc
    13741 agccacgccc acagaatgcc ggtgacgagc gccacgctga caacgactgg aacaaaatac
    13801 ccggccacca catcggctgt gcgctgaata ggcgcacgac tgcgctgagc ctcggccacc
    13861 atttgcacga tgtgggacaa cagcgtatcc gcgcccaccc gatcggctcg catcaccacg
    13921 ccacccgatc cgttgatggt gccaccggtg acccgctcac cggcaaactt ttcgacgggg
    13981 atcgattcgc cagtaatcat ggactcatca atcgaggtcg ccccttcgag aatcactcca
    14041 tccaccggta cccgttcacc aggacgaacc cgcaaccgtt ggccgacctg cacctgttcc
    14101 agcgggacat cttcttcacg gccatcatcg aacaaccggc gggcggtctt cggggccaag
    14161 ccaagcagcg ccctgatcgc tccggtcgtc cgactcctgg cccgcagctc caacacctgg
    14221 cccaagagca ccaggacggt gatcaccgcg gccgcttcga aatagaccgg caccgcgccg
    14281 ctctcgagat ggaaggattg cggaatcgaa aacggaaata gcgtcgcgat cacactgtag
    14341 agataggctg tcccggtgcc gatcgcgatc agagtgaaca tgttcggact gcggtgcaca
    14401 atcgacgccc aaccccgctg aaagaacggc cagccggccc acagcaccac cggcgtgctg
    14461 agcacgaact gcacccaggc cgactgggta tccgacagaa gatgttggat cggatggccg
    14521 ggaagcatgt gcgacatggc caacagaaac acgatcgccg ccggtcccaa tgccacccag
    14581 aaccgtctgg ccatatcgac cagctcggga ttcagttcct ccgcgacagt gaccgttcgt
    14641 ggttccagcg ccatgccgca cttcgggcag gcacccggct ccgcctgcac cacctccgga
    14701 tgcatcgggc agacatattc cgtcttggtc ggcagcggtt ggacggaatc cggttccaga
    14761 gccatgccgc atttcgggca agggaccggc ttctcctcca atacttccgg acacatgggg
    14821 cagacatact tggttcccgg agggaccggg gttgcaggca tcgcatcttt gacggagccc
    14881 ggcgataggt agcgcgccgg atcggcgcgg aacttggtga gacaaccttg gcagcaaaag
    14941 aaataggtcg tgtcttggta ggcgaaggaa ccagccgccg tcgccggatc caccgtcatg
    15001 ccgcagaccg ggtcgatgac agccgccgcg gagggcccgg gggacgaggc ggcccccaac
    15061 atgggtaagg cctttcctcc gaactgacgc agcgatgtcg atgcaggagc ggcgacggga
    15121 gccaggtacc gacccggatc ggcccggaac ttttcgagac agccctggca acagaaataa
    15181 taagtcttct gttcatgggt atgagagcca gccgccgtgg ccggctcaac catcatcccg
    15241 cagaccgggt cccgttcgcc gcctgtggtc gcttcttgcg caggcatcgc ctgcatcatc
    15301 ggtagcgagc ggcgactgga tggttggacg gcggcaccgg cgggggcggc cttcttcacg
    15361 tagtgcgccg gcgcggcgcg aaaccggtcc cggcatgagg ggctgcaaaa atgataggtc
    15421 tcgccctcat attccgcgta ccctgccgcc gtggccggct ctaccgtcat cccgcatact
    15481 ggatcacgtg ccattcgcgc ttgtacctcg tcgttcgtcg ctcgtatctc gtcgctcgtc
    15541 ggttccgtct tacgtttcac ctttcacgtt tcacgaaata cgcttcacga gatacggcct
    15601 cgttactttt tgctgtctcc gtccaggatg ctttggatga tcagcttcaa attctccggg
    15661 tcgatttgct ccaccttgat gttgccgtcg agcaacacgg tcggagtctg ctggatcttg
    15721 atgcgatcgc cccatttccg cccgtcttcg aacgccttcg ccggtttcgc actggccagc
    15781 ccttcttcga aagccgccgg attcagtccg acctcgcgaa tcaagacttc acgaatcgcc
    15841 ttgtcgatga tgcctacctt gtctttgtga atggtccgga acagcgcccg cttcatttca
    15901 ttgcccttgc ccatactctt ggcctgctca tacatatcga aggccgtcgg caacttgccg
    15961 gggatgacgg gatagcccac catgaccgct tcgactttgt ttccgaattc cttctccaga
    16021 atcatcagcc cttcgccatc gaaccggtgg caatgcggac aatagaagtc ggcgaactcc
    16081 accaactgga ccttacccgg cttgtgggtc gatttttctt cgctcaagac ctggaaatta
    16141 cccttgagtt cgggcttcgc cgcttgcgct gtgcccgcca atcccacaag cgccatcacc
    16201 atcacgccca cgaacagacc accgtgccac acacgacgca tcaccatacg ctgcactcct
    16261 ttttcaaaca tgaatcgttg ccacaggctc ctcggcatta taaacaatgc tggcactctt
    16321 ctgcgtctgt tataatgcca acgatgcgtg ggaaacttct acagggtctc ggtattttgt
    16381 gcatggccgc gatcctggcc gcttgcgcga cctccgccga tcagcgtgaa gccgaagacg
    16441 gcgcatccca gacgccgcaa ttttcgcaaa tcaaagctgc cccggaatcg tttaaaggac
    16501 agaccgtcgt gctgggcggc caagtcctct cggcccggcg gatgaaagac ggaacccgcc
    16561 tcgaagtgct tcagttgccg ctcaatgacg cgcaacagcc atctctggat ctgaccaaat
    16621 cgcagggccg attcattgcg attcgccggg aattcctgga tcctgcgacc gtgccgcagg
    16681 gcacctttgt caccattacg ggccagatga cgggctccgt cactcagccg ctggatgaga
    16741 ccgactacgc ttacccggtg ctggagatca ccacgtttcg cacgtggatt ccttctcagg
    16801 atttgaacct tcctcggtac cgcccctacc cctattacag tccgttctgg catccctatt
    16861 ggggaccgta cggacgtttt ccttactatt ggtagcaccg tcacccgcac tctcgcctgg
    16921 aatcatcgcc cgttttctgc gccttgtcgg accgcatgct cgagctgatc gtggcttacg
    16981 gccctgaacg acaacgcccc gtccatccgg agatgaacgg ggcgctgcga gaaccgaatt
    17041 gattcggtgt ttacttgatc atgatcaact ggccgccggg ctgcttcggg ttcaattgat
    17101 cccgataggt cagggtgttg ccctgggtgg cgttgaacaa atcgctggtc ggcacaccga
    17161 tgtacttcgt ctcaccgggc ttgaggacca cttcagcctt cagcacgaac ggagaggctg
    17221 cgttgaccgg gtccgtcatc tggaagccac ggtcagaaga cgtgttgttc gtcaccttca
    17281 gcaagaccgg acggccggga cggactttga agtcgatgat ggtggtcggt gggtaccacg
    17341 ccttcaggcc gcccacttcg accgcaaaca actgcgcatc cacttccaac tccttgaacg
    17401 gttggccgac cacagaacca gtctcaaggt cgcccacctc gacgccgccc gcctgcaacg
    17461 cccaggctcc cgtggcgctc gacaacagac tcaacgcacc aaacaatacc actgcactcc
    17521 tgctcaacat acacaacctc ctgtcgggtt aaagagatga agacgaacga tgctccggag
    17581 ccaggcacgg gggaagacca gtgccttcca gcacctgacc gccaacaatg agaccatcca
    17641 cgatgagaaa caacaccttc atgcgcttcg tgctgtctga aaatttgccg ctggcgatgg
    17701 ccagcacttc atgcgatccg tcgggctgag gatgatctgc ttcgatgttg acataataga
    17761 aatcaaatcc ctcgaactcc ttattgaacg cctgggcccg caacagatgc tctagcgagt
    17821 cgtcggcccc ccatcccgcg gttccaccgg ccaccaccag aagttggatc aggacgatac
    17881 agacacatcg catgaggcta cctccctagg gtgggagtta tagcctcgag gcacccggtc
    17941 gtctacagac gcacgctcat ggatgcttac gggtgctaca gtatcgtttc cggaccacca
    18001 acggcaagag gttatacagg attacggcgc ctgagggaac caggggaaga ccgagggtag
    18061 aactggaggc tctggcagga agccacgggg gaagcggaat ccttgatgct tcccaccgta
    18121 gcctcatcgt tcggttagtt gccctttcct ttgccttttt tgcccgaggc ctgttcggca
    18181 tgggccaggg attcttccgc atgcttcaca gcttctttgg catgctctaa cgcctccttc
    18241 gcatgcggat cgttgctgcc cttcaccgct tcttccaagt gcttgatcgc ttccttctca
    18301 tgctccacgc cttccttggc atgcttgatc gtttctttca catgcccgcc gccgtcggcc
    18361 agcgccatgt ttgccggcgc gaccgccacg agcgcacata gagacgcaac cactactcct
    18421 gcacgtaatc ctgtcatacg cattcctcct gtgtcatagt gaaccgttgg ctgattggcc
    18481 gcattctaca gcattttgta gacggtgttg agcgagatgg tggtattgag agtggtcacc
    18541 gggaaagaaa aaggtgggag agggaagcgt atgggcgtac gcctccctca tcggagctca
    18601 ctgcgtggtc agcgcagtcc aaccgacgag ctccgtccac cgatcgtcag gcagaggccg
    18661 gggtgagcca cggcaaacgg cagatgccac accgcccggg atccgctctc gccgactggc
    18721 cgccggaatc ccagctcgca tagatccaca attcagactg tgccgtcccg acctcgtctc
    18781 tcgtcatccc cgcgcatttt tccatgacaa acaccgctgg acgagattcc tgcgcgccga
    18841 ttcctaccgg acagggttcg gattccacca cgaacaccgt ccccacggga aatgatcgat
    18901 catccgccgt gaggagcccc ttcgggcaca cgtaaaaccg gagctcttgc gctccgccag
    18961 acgactgcac aagcgacgta agatggggcc agtctcgata cccgaacggg atcatcaatc
    19021 cggctgcggg cggagccggc gaccaccctc cgctgatgtc caacgccagc gccaacaagc
    19081 gcaccaccgc tacattcaat cctgtctggt cgtacggctt cccggcgacc gtcgttcgtt
    19141 gaggagatgc caccgcgtca ctgaccggca tggaccacct tcctttctga tcggggcaca
    19201 ggttatcgac tggcttctcc gaccgtcgcg ccaaggtaag agaccgcgcc ctgcttcacc
    19261 gctccgggct gagaccgtgc gcgaatcgat gcggcgcgcg ccgcatatag tccggcctcc
    19321 accgattggc cgatgctgtt gagtaccact gcatatcgtt ccaccaggag tccaaccgtg
    19381 gggtggtgca ccccgagctg ctgttgctga atcaccagcg cgcgctgata ccacagttgc
    19441 gcctgagcca tcagtccctg ttgatcggcc aggaacgcca tgttgcctat aatcgtgccg
    19501 gccagagcgc tctgagggcc ggagagccgc tcggcgagcg gcaaggcttc gtcgaaatgg
    19561 cgttgcgccg aggcatacag cccctcggct tggtacaggc aggccaggtt gttcaaactc
    19621 atcaccacag ccggatggtc gttgccgaag cgaagccgac ggaccttcaa ggcccgttcg
    19681 tacaacggtt cggcccaggc atacatcccg cggcccttgt ataacgcagc caggttattg
    19741 agcaccggcc ccagctcaac atgatcgggg ccatgcgcct gctccatcag cgtgagcgcc
    19801 aatcgatacg tcgattcggc agccgtctct cgcccctgct tgcggtagag ctcggccaga
    19861 ttgttcaagc tgatcgcgac atcgggatgc gccgggccca gcgtctggcg ttcgatcttc
    19921 agcactcgct catacaatgg ttccgccgca gcccactcgc ctttggcatg ggcgatttcc
    19981 gccagattgt tcaatgcggc ggcgacgtct tcgtgctccg gccccagttg agcctcccac
    20041 gtgccgagcg cgcgcagata gagtgcttcg gcttctgaga gccggccctg gtcgtgatac
    20101 aacaatccca gctggttcgc ggccagcgcc actcgcgcgt catcggcacg actctgcgcg
    20161 gcttcccgca gggcctgcgc caagagcggc tcggcttcac cataatgtgc ggcttcgcgg
    20221 gcctttaccc cctcctcgaa gcgctgcatc cagccatccg gttccgtcgc gccgctcccg
    20281 gtggcggcgc ataagactat cagcgcgacc aggctcacga atcccattcg ataccaccgc
    20341 cggttcatgc gatcactcat gatggtcgag tcctccacac cttcgatcga ctccgggctc
    20401 attccgtcgt tcccgttcct cgcgcctgtt tttaccttgc cagcccccga agggccgggg
    20461 tgaaggggga ggcc
//
LOCUS       DAOQPD010000070        20067 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1325_length_20067_cov_23.985609, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000070 DAOQPD010000000
VERSION     DAOQPD010000070.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 20067)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 20067)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20067
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1325_length_20067_cov_23.985609"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..621
                     /locus_tag="PK063_14385"
     CDS             <1..621
                     /locus_tag="PK063_14385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HMZ98287.1"
                     /translation="VARRVGLGLAMIARLGLLFSISFVMGLTKPWVTVLGHGISGRDL
                     ILVGGGLFLMAKATHEIHNSLEGVEEGHSPTAAASLGMVLVQIALLDIVFSLDSVITA
                     VGLVEHVSIMAAAIILAVVVMLMAAKAIGDFVETHPTIKILALSFLILVGVTLMVEGF
                     DVHVPKGYIYFSMAFSVTVEMLNIRMRKKRAVPVKLHSRYAEEPRQ"
     gene            complement(649..1191)
                     /locus_tag="PK063_14390"
     CDS             complement(649..1191)
                     /locus_tag="PK063_14390"
                     /inference="COORDINATES: protein motif:HMM:NF015782.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Slp family lipoprotein"
                     /protein_id="HMZ98288.1"
                     /translation="MNGLLTRLLACSASLILVTACSTLPSKYIEKAEPGVTLTSLAAA
                     PETYQGKTVILGGVVVDQQQQGQRLWLHVKNRPLDKDYRPHRPTINEGPEAGYYWVVV
                     PDASLLPPKWKQWARVTVVGRVMDQRETRPTTVPTSEPVLSLVFMRGWAMGNAQGKGA
                     WEESVDANYLLSVPEGLHGE"
     gene            complement(1232..2041)
                     /locus_tag="PK063_14395"
     CDS             complement(1232..2041)
                     /locus_tag="PK063_14395"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HMZ98289.1"
                     /translation="MSRSSASPSTRWPLPAQDDWSTPFAELLLAQLDLHSGLTILDIA
                     CGHGIPAFYLAEHVGPTGSVLGIDMSRGQVANARTVQRGELPWLRFECVDMRALPPSF
                     PTFQRITGNLSVMFLRPHRFEAMRGLIAHLEPGGQIVLTFPSLGTFDSMWQRIDREMS
                     RHGLTMERERLAAHVAERPSAAEARGWLEQLKMERIDVIEQPLEVPSGAGQRFLQHPL
                     LRGGFLDDAYECFDDARLADTVMTSVAADLESMMPLVARRCALSGWKPRQA"
     gene            complement(2133..2876)
                     /locus_tag="PK063_14400"
     CDS             complement(2133..2876)
                     /locus_tag="PK063_14400"
                     /inference="COORDINATES: protein motif:HMM:NF021378.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HMZ98290.1"
                     /translation="MAPGTERPCFSCDDQRLVRMVPLEKGTHQKLLLRHPLVLQQQEW
                     EALLRMVKVRSIHRPLLGATYQGDTEPLFSEEEVRYLGDSLQRAFQQATPQEHVVFAL
                     ARPSQTGLEQITSGAWFVEDGLIHLRVANCRIAVTMPSIRKQIWKDPLFAQAGAFYEF
                     VPGGGQAIARATVDGGNPFRSDPDELVIEYKIASSANPAPVSSEPSAQPVPPRSLEEQ
                     LSLLKRLLEQGLITEEDYRTKKQQLLDRL"
     gene            complement(2988..4457)
                     /locus_tag="PK063_14405"
     CDS             complement(2988..4457)
                     /locus_tag="PK063_14405"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98291.1"
                     /translation="MKMSTLRARAVIVAILILLGLISYELSGLVQKAEAIPAFGRKYD
                     FKCNVCHVPGFPKLNDFGNLFRDRGYQLGSDADSPVYEGIGMGFWPVSIRATVGYQAA
                     QLRTEGSGVTTGGFGFTGLDLLSFGTLHRDIAFGVVYTPGLGSAGFGTGASDGDLESA
                     FVRLMRLERYFGVKSDPGNYLLNLRVGKFELDLPFSEKRSPTLNTPFVMYHYTPGVPY
                     TATIGGTSTSSYLNPNSFLLGDNQPGGELSGIMKTPSTEGYLRYSLTALATNSFSGPL
                     GGCPPNTPCGTGGRNVNFYGHITQSFGGYGIVTGNRVGIFGAYGQAPTMVNATCPTCQ
                     GVAGSGKPFTRIGVDVSLTFNGEWNIFGAIMHGHDSAQLFASQGIPTPQNASWNGAFV
                     ELDYAPALFFDMPDWFFAYRYDVIRNDRHGDGNTDVFKGNYNDVDSHTVLARYFIHHS
                     TRTDLALHAEYNSYRTQAVGPTGGDLRGQTMLVGLDFAY"
     gene            complement(4497..5360)
                     /locus_tag="PK063_14410"
     CDS             complement(4497..5360)
                     /locus_tag="PK063_14410"
                     /inference="COORDINATES: protein motif:HMM:NF026037.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase-like regulatory
                     domain-containing protein"
                     /protein_id="HMZ98292.1"
                     /translation="MSPRRHRGFRLVLLSCLAWLLTAISGYAEYEIIDVSDGGTVKGQ
                     AVWKGSIPKLPPLKVFADLDSCGTHVPSPALRIDPATNGIHEVLVYLERVERGKSAAT
                     AYPLRMGKSASHPTGRACQFERHMIPFVRTAEVALINFEPILHNPHLFSEKQSLFNIA
                     MPTANREIATTLGRARGVGLRLQCDVHVHMNAWAAALEHPYFAVTDEQGKFEIAGIPP
                     GSYTLVAWHPGFNIVKFSASRPVYDEPHVIRQPVEVSSKAQVESRFEFPVRPVEVEWN
                     IAGGGDELPPE"
     gene            complement(5616..6629)
                     /locus_tag="PK063_14415"
     CDS             complement(5616..6629)
                     /locus_tag="PK063_14415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HMZ98293.1"
                     /translation="MAGRPLVPDHILQIGFGFWSSKTLLSAVELGLFTLLAKRQLDGK
                     ALAARLKLHPRSARDFFDALVALKLLKRNGTRYANTPETALFLDRAKPTYVGGMLEMC
                     NARLYGFWGSLTEGLRTGQPQNEVKTGEDFFGTLYADPQRLEGFLKAMTGLSKGTARS
                     IAAKFPWKRYHSFADIGCAQGGVAVEIALAHQHLNGQGMDLPVVRPVFESYIRSKKLQ
                     KRMTFHEGDFFKDSLPKVDVLIMGHILHDWDLKEKMMLLRKAYAALPPGGALIVHEAL
                     IDDARKTNAFGLLMSLNMLIETPGGFDFTGADCRQWMKKVGFTRTKVEPLAGPDSMVI
                     GFK"
     gene            6900..7643
                     /locus_tag="PK063_14420"
     CDS             6900..7643
                     /locus_tag="PK063_14420"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98294.1"
                     /translation="MATYLHVKAALTALVLFSIMTATAGAEQWNGPQTPTGTIWRPGN
                     IALGFDPAGHSGTPPALEIRRPLSGTEEVLLSLRSTFKEATATVLEVDTKRVYMGGAA
                     TRTSLMPDGVFDLAVGRGIAVGVNSVTERLPTDYRLVVGGKVLAEEVRIKLIKDWADY
                     VFHPDYRLAALPEVATYIQSHQHLPDMPSAAEVAATGISLGDMQAKLLRKIEELTLHA
                     IEQHQTIAALQARLQQLEEDRSSQQLGSK"
     gene            7681..8598
                     /locus_tag="PK063_14425"
     CDS             7681..8598
                     /locus_tag="PK063_14425"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98295.1"
                     /translation="MTQFTALTTALLLATLTLPAEAGTTSLTLNQVIKEGTARYYDHP
                     QELRLADGFWAQAGSDMTATIHLQQGYYLDKTPLDTKEKQYTSTDGRTYLVAGCVPKH
                     LPISGPVGSVWVACNDLDYLKDKVVESRFVSCLDVFTNGVVSGVSIKEVNNRTWESFR
                     FSCRDMGPDGSMVGAAQKSDFLFNYEREGKLYETTTASGHLTFGILEVANGLTGTKSL
                     LQIALEHTAAAALQAAGVNGRHVDDFTLSDKVPDAFGLGGMLRVDHWKCPPGMVITGM
                     AIGHNPDKKGNDTKPVYILAECRKLLYTP"
     gene            8763..9428
                     /locus_tag="PK063_14430"
     CDS             8763..9428
                     /locus_tag="PK063_14430"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98296.1"
                     /translation="MATMLQKALQGLLLVLLVGCSTTYEPHLVLPPAEFNRSIDAAVE
                     VHPFVAADDLLYGRSNYGVVADDYANKPPSKLTQSITQQVTAELAAHRVFRRVSTYDP
                     APDLILTGRIERFFEHDRRKLWTFIPYYSDKLASLFRVNSFKTNGEIHLTLTLLKPTG
                     EVVGSYVGHASFDEDYTPNGEVRPGDRLNRALGQALAQIRDEMFADSTLTKSRTPHPL
                     ALQ"
     gene            complement(9479..9934)
                     /locus_tag="PK063_14435"
     CDS             complement(9479..9934)
                     /locus_tag="PK063_14435"
                     /inference="COORDINATES: protein motif:HMM:NF014573.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HMZ98297.1"
                     /translation="MLDVPVLRTNEDFEKGQAPDSIRRAEESMGWAGHLVIVCPLWLG
                     SMPALLKAFFEQVFRSGVAFQYQPDATRAKKLFAGKSARVVVTMGMPAWVYRWWYHVH
                     SLKGLQRNIIQCCGIKPTRATLIGNIESMNEQRRASWLDEMRGLGERGQ"
     gene            10632..11069
                     /locus_tag="PK063_14440"
     CDS             10632..11069
                     /locus_tag="PK063_14440"
                     /inference="COORDINATES: protein motif:HMM:NF012780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HMZ98298.1"
                     /translation="MRATEYFARGCDPNTLVVRQIMEDAVVTIHPTSSAMAVAEILSE
                     HSFGSVPVVDKDGTLRGLVTEFDLLKAVEQERDLRSVLVSDIMTKDVVTTTEETPIMS
                     LIHLLQERHLIRVPVVKGQKLVGMVARRDVVFAYVKARAIYWP"
     gene            complement(11124..>11741)
                     /locus_tag="PK063_14445"
     CDS             complement(11124..>11741)
                     /locus_tag="PK063_14445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2238 domain-containing protein"
                     /protein_id="HMZ98299.1"
                     /translation="LLLGYGIIWIWLAINPVNRHDWVLENLLAVGLVAILVLTYRRFT
                     FSLTSYSLIAVFMVLHAIGAHYTYAEVPFGFWLKDIAGLTRNPFDRLVHFSYGLLLVY
                     PLREVLVRLAGVQGSWSYVMPVSSILAQSAFFEVIEAIVAMIVSPELGSMYLGTQGDE
                     WDAQKDMAAAFGGAIVTMVMTAALSAPRNSQVQQPSHRSAPSVAH"
     assembly_gap    11742..11841
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            12106..12834
                     /locus_tag="PK063_14450"
     CDS             12106..12834
                     /locus_tag="PK063_14450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HMZ98300.1"
                     /translation="MPMPLLDIRSLSVVVDGQVILDRLDLAVQGREIHALVGANGSGK
                     TTLAYVLMGCEGYSPSAGHVLFNGMDLLRLKMHERARLGLTLAWQEPARFEGVTVREY
                     LSLGKPECDPEPALKQVGLDPDRYLTRRMDKALSGGERHRIELASVLSMKPKLAILDE
                     PVAGIDMLSIHHIIEIIRALKASGGSVLLITHQEEVVLIADRASQLCGGRIIFSGSPS
                     EAVDHFRGRSCVRCDGEVCGYVRP"
     gene            12821..13756
                     /locus_tag="PK063_14455"
     CDS             12821..13756
                     /locus_tag="PK063_14455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HMZ98301.1"
                     /translation="MSDLEELMRVLPRVGAEPSILDDTGIAHVVAHGHHILSHRTVPG
                     LRVDIQETPEAIIGKIVVEAGVTIAQPVHLCFGLAHPTGTQRITMDMQVNEGAQVRVL
                     SHCLFPFVQDGQHRMQAVMTINPGASLTYTEGHYHGPYGGMQVLPHATIKIGKGARYF
                     SDFSLLSGSVGNLDINYLVEVEEDGLAELSAKIFAHQRDRLTLKEAVMLRGERSRSLI
                     KTRVVLEDDATAEITGITEAYAKGTRGHVDCMEVVQGRAHASAIPIVKVFHPEAKVTH
                     EAAIGSVDKKELETLMARGLNPEQAVELIVSGMLR"
     gene            complement(14146..15189)
                     /locus_tag="PK063_14460"
     CDS             complement(14146..15189)
                     /locus_tag="PK063_14460"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HMZ98302.1"
                     /translation="MRLVVTIDVEEDQWGIVPHGQATAQNVYRLPRLQALLNEFGIIP
                     TYLVTYPVMQDSYAVGILREIVEAGECEIGAHCHPWNTPPFKEPLSKRNSMLCNLPAT
                     LQYEKLQRLHEAIQYNVDRSPRAFRSGRWGFDTEVARNLLRLGYRIDTSVTPYTSWVQ
                     TAGPDFSCCSPQPYGFAPNVHTGRSSNEVLAEIPATIGYLHGEFQACATLADRLNRAP
                     FGRFRVGGLLSRLHLLRKVWLSPEMETPARMMQLVRQMRHQQYEWLNLVFHSSALLEG
                     CGPFVRSRADEQAFLKRLRTFLCAAVKEGILCVSLSEAARHFIPASGEPAATPDSSSL
                     MAKCPAFSSQPFA"
     gene            complement(15233..16357)
                     /locus_tag="PK063_14465"
     CDS             complement(15233..16357)
                     /locus_tag="PK063_14465"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF024871.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HMZ98303.1"
                     /translation="MKQRRRLTIQVVTTPEEFKGLAGAWETLLDRMPGHSMFLTWEWL
                     YYWTLHYLGDSQLRILLAFDEHETLVGIAPLYLRRTKKHAVFAVRELRLLGSEAVCSS
                     YLDLIVQEQHKLAMLQSLYHYLFGDARDEWDLLTLSDLSAESSTLDLWNGLVAKAGKV
                     GDVSTTSCCPVIRLPADLPTYRASLGRNRRYTIQRKTRCLQQAGRMQFTRATSPADVE
                     IAFESVITLHQRRWSSRPGGGVFANEQSRRFHRDIVRVLSERGRVRIDLLLLDDRPIA
                     GVYGFLYQGVYYFYLPGFDPDILPKASPGLLLLHRVIEQALCDGAQMVDLLQGSQPYK
                     LEWSTGLCRLVTSRCYNRSASGAAVTLLDGAKQALKILLR"
     gene            complement(16354..17943)
                     /gene="xrtW"
                     /locus_tag="PK063_14470"
     CDS             complement(16354..17943)
                     /gene="xrtW"
                     /locus_tag="PK063_14470"
                     /inference="COORDINATES: protein motif:HMM:NF038142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosortase W"
                     /protein_id="HMZ98304.1"
                     /translation="MENSLVTPSATGTRPTSAGVHSRTPAYLLRNYSALWRITGLCLP
                     LLLLCAPVLHDLLDLWWNRYGFSHGFLVPLLSLYLVRLQWPTLKQLPVEPALGAGLLW
                     LVGAIALLLASEVAGILTTGSVALILVLAGLVLLLCGFAYLRALAFPLAYLIFMTPVL
                     DGLTEPLVWPFQLLTANMSVSMLRALGIPVILENSIDIILPTVTLEVARECSGAGLLI
                     AVLAIGLPLAALTLQTWWARVTLLLSSVAIAIMANWLRLTVMGVYAQAGGKDLHGPYH
                     ILQGLFVDWVAFAFLFAGAWLLGRLEHVPLRPSIHGEEKKCFSEPVSHRHASNRAWWL
                     ACVTLSVATLVLYGLDRGASGLKKELATFPGVVGDWVVDHRLNSASPVSLAAADDSLM
                     RTYRDSDGRRVNVYVAYTKSQRQGKELVGMETAPLHTGAIAAMLGRREDAIAVNRTVF
                     DERGRPVPSLFWYHINGSSYTDRVEAKLATIKQALLRGRTDGALVLVSAEPRSRENDD
                     PWKAQEEFVASALPLLREYLP"
     gene            complement(17985..>20067)
                     /locus_tag="PK063_14475"
     CDS             complement(17985..>20067)
                     /locus_tag="PK063_14475"
                     /inference="COORDINATES: protein motif:HMM:NF024299.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ98305.1"
                     /translation="HEVRGDGYVQQEQFREAMIEFKNAVRAAPDNPSLQWKLAKAALK
                     GGDPSTAYQALGRVVQLDPSHFEAKWSLGDLYLAGGKMDEVGKIAEELVSANPQHPAG
                     YLLRAAVALRAERNADAIAILKQAVTLDPKMVGPHLALANIHFAQQDIEQAAEWYDRG
                     VKADPASAGARIARGQFLFATGAPEEGRKEFHKAVELSSDQESIKLVLAERYAMLGLR
                     EDAEHELSALIADRHSQRARKALAELKLTLGEVAEAKPLLQAILAADEHDPVALYLKG
                     RVAFAERDLLQAASLFEAAIGRDTTLVGPHVYLGLIRSTQGRMDQAEEALREAIRRDP
                     SNQTAHLALARLYLTQEKPKEAEKEVSQTLRVNPASLEAAVLYGDVFVFGKNWARAEE
                     VYGAISRQLPGQPIGYVKMAALRQLQARPAEAAELFAQALVYAPDDPVIMQDYLVTLV
                     GSKQSQQADRVLGAYLAKTSRDPNTWRLAGRVYVAQGKIDQAQKAFRKAVDLAPDLAL
                     AHYELGQVQLLQNKLPAAVSAFQSALKKDETNSAIHTALGMVLARRGQVDAANGHYKR
                     AFQLNPRDVVAANNLAANLSDQQELDDALGFARDALELAPSNPAIKDTLGWIYFKQGR
                     FDRAYPYLAEASAALPQHPVVRYHHAVALSKIGRQTEALSELKSALSLPGGFPEAEQA
                     ARMVASNKMDE"
BASE COUNT         4411 a         6013 c         5548 g         3995 t
ORIGIN      
        1 gtcgcccgcc gagtggggct gggtctggcc atgatagcca ggcttggatt gctgttttcg
       61 atttcctttg tgatgggatt gaccaaaccc tgggtcacgg tcttgggaca cgggatctca
      121 ggccgtgacc tgatcttggt cggaggcggc ctgtttttga tggccaaggc cacacatgaa
      181 attcacaata gcttggaggg tgtcgaagaa ggccactcgc ccaccgctgc cgccagcctg
      241 ggcatggtat tggtccagat cgcgttgctc gatattgtgt tctcgctgga ttccgtcatt
      301 acggcggtcg gcctggtgga acatgtctcg atcatggcgg cggcgatcat tctcgccgtg
      361 gtcgtgatgt tgatggcagc caaagccatc ggcgattttg tcgagacgca tccgacgatc
      421 aaaatattgg cgctctcgtt tttgattctg gtgggcgtga ccttgatggt ggaagggttc
      481 gacgtgcatg tgcccaaggg ttacatctat ttctccatgg ccttctccgt gacggtcgag
      541 atgctgaaca ttcgcatgcg caaaaagcgg gctgtgccgg tcaagctgca tagccggtat
      601 gcggaagaac cgcggcaatg aggggccctc aggccgttct ctccccgcct attccccgtg
      661 aagtccttcg gggacagaca ggagataatt ggcatccacc gattcctccc aggcgccttt
      721 tccctgggca tttcccatgg cccacccgcg cataaatacg aggctcaaca ccggctcact
      781 cgtcggcacc gttgtcggcc tcgtctccct ctgatccatt acacgcccca cgaccgtcac
      841 ccgcgcccac tgtttccatt tcggaggcag gagggaggcg tcagggacaa ccacccagta
      901 ataccccgct tccgggcctt cgttgatggt tggacgatga ggccgatagt ctttatcgag
      961 cggccggttt ttcacatgca gccacagccg ctgtccctgc tgctgctgat ccactaccac
     1021 cccacccagg atgaccgtct tgccttgata tgtttccggc gcggcggcaa gagaggtcaa
     1081 ggtgactccc ggctcggcct tctcaatata cttggatggc aaggtactac aggccgtcac
     1141 gagtatgaga ctcgcagaac atgccagtaa tcgagtcagc agaccgttca catcgtcctc
     1201 cgttcgtcgc aacctcgatg caccgaagca atcaggcctg acgcggcttc cagccactga
     1261 gcgcgcaccg cctggccacc agcggcatca tgctctcaag atccgccgcg acgctggtca
     1321 tcactgtgtc ggccaaccgg gcatcatcga aacattcata ggcatcgtcg agaaatccac
     1381 cgcgtaacag cggatgctgg agaaaccgtt gcccagcccc gctcggcact tcaagcggct
     1441 gctcgatcac gtcgatccgc tccatcttca gctgttcgag ccaaccacgc gcctccgctg
     1501 cggacggccg ttccgccaca tgcgcagcga gccgttcacg ctccatcgtc aacccatgcc
     1561 ggctcatttc tcgatcaatc cgttgccaca tggagtcgaa ggtgccgagc gagggaaagg
     1621 tcagcacgat ttggccgccg ggctcgagat gtgcaatcag tcccctcatc gcctcgaacc
     1681 ggtgcggccg gaggaacatg acggacaaat tgccggtgat ccgttggaaa gtgggaaagg
     1741 atgggggcaa ggcccgcatg tcgacacatt cgaagcggag ccagggcaac tcacctctct
     1801 gcactgtcct ggcattggcc acctgcccgc gactcatatc gatcccgagg acggagccgg
     1861 tcggccccac gtgctcggcc agataaaaag ccggaatgcc gtggccgcag gcgatatcca
     1921 ggatggtgag accggaatgc agatcgagtt gcgccaagag cagttccgca aagggtgtgg
     1981 accagtcatc ctgcgcagga aggggccagc gcgtagaggg ggatgcggag gacctgctca
     2041 tgacattcct ttcgccgggg gtgatggctc tcagccgcat cttacccgaa gggtaaagga
     2101 caagtcagaa atctcttcgg tcaccttcac gctcacaacc ggtcaagcag ctgctgcttt
     2161 ttcgtacgat agtcctcctc cgtaatcaaa ccctgctcca gaaggcgttt gagcaagctg
     2221 agttgctcct ccagcgagcg tggcggaacc ggttgagcag agggctcaga agagaccgga
     2281 gccggattcg cagagctcgc gatcttgtac tcgatcacca gttcgtcggg gtcggaacgg
     2341 aacggattcc cgccgtccac ggtcgctcgc gcgatcgcct gccctccacc tggcacgaat
     2401 tcataaaacg ccccggcctg cgcaaacaag ggatctttcc agatctgttt cctgatcgac
     2461 ggcatggtca ccgcgatccg acagttcgcc acacggagat ggatgaggcc atcttcgaca
     2521 aaccaggctc ccgaggtgat ctgttccaat cccgtctgcg acggcctggc gagcgcaaac
     2581 accacgtgct cctgcggggt cgcctgctga aaggctcgct gcagtgaatc gcccagatac
     2641 cggacttctt cttcggagaa cagcggttcc gtgtctccct gataggttgc gccgagcaga
     2701 ggccggtgaa tgcttcgcac cttcaccatt cgcagcaggg cctcccactc ctgctgctgc
     2761 agcaccaacg gatgacggag cagcagcttc tgatgggttc ctttctcgag cggaaccatc
     2821 ctgacgagcc gctggtcgtc gcaggagaag caaggccgct cagtgcccgg agccatgccc
     2881 gaacaacctg agacggcgag acacgaaagc catagcacag cgacagttgc cccgcgacga
     2941 aacggatggt tcacagaact ataacctttc ttctgggcag acgattctca atacgcaaaa
     3001 tccaatccca ccagcatggt ttgccctctc aaatcacctc cggtcgggcc gacggcttgc
     3061 gtgcgataac tattatattc cgcgtgcaag gctaaatcgg ttcgcgtgga gtgatgaatg
     3121 aaataccggg ccagcacggt atgggaatcc acatcgttgt agttgccctt gaagacatcc
     3181 gtgttgccgt cgccatgccg gtcgtttcgg atcacatcat agcgatacgc aaaaaaccag
     3241 tccggcatgt cgaagaacag ggccggcgca tagtccaatt cgacaaacgc gccgttccac
     3301 gaggcgttct gcggggtcgg aatcccttgc gaggcgaaca attgggcgct gtcatgtcca
     3361 tgcatgatcg ccccgaagat gttccattct ccgttgaagg tcaggctcac atcgaccccg
     3421 attctcgtga acggctttcc gcttcccgcc acgccctgac aggtcgggca ggtcgcattg
     3481 accatcgtgg gggcctggcc gtaggccccg aagatcccca ctcgattccc ggtcacgatg
     3541 ccgtaaccgc cgaacgattg cgtgatgtga ccatagaaat tcacgtttct cccgcccgtc
     3601 ccgcatgggg tattgggagg gcatcccccg agcggccccg aaaacgaatt cgtcgccagg
     3661 gcggtcaacg aatagcgcag atatccttcg gtagacggcg ttttcatgat gcctgacaat
     3721 tctccgccgg gctggttgtc tcccaacagg aacgagttgg gattcaaata ggaactggtc
     3781 gaggtgccgc cgatcgtcgc ggtgtacggc acacccggtg tgtagtggta catgacgaac
     3841 ggcgtattca acgtcggact gcgtttctcg ctgaacggaa gatcgagctc aaactttccg
     3901 actcgcaaat tgagcaagta attgccggga tcggatttca ccccgaaata ccgttccaga
     3961 cgcatgaggc gcacgaacgc gctttcaaga tctccatccg acgcgccggt gccgaacccc
     4021 gcgctcccga gcccaggcgt atacaccaca ccgaacgcaa tatcgcggtg cagcgtgccg
     4081 aaactcaaga ggtccaggcc ggtgaaacca aaccctccgg ttgtcacacc actgccttcc
     4141 gtccgcaact gcgcggcctg atagccgacg gtcgcccgaa tggaaaccgg ccagaaaccc
     4201 atgccgatcc cctcgtagac cggggagtcc gcgtccgatc ccaattgata tccgcgatcc
     4261 ctgaagagat tgccgaagtc gttgagcttc gggaatccgg gcacgtggca cacgttacac
     4321 ttaaaatcat acttgcggcc aaaggccgga atcgcctcgg ctttctggac cagcccgctc
     4381 aattcgtaac tgatcagccc caacaggatg agtatggcaa caatcaccgc cctggcacgt
     4441 agtgtagaca tcttcatcgg atcagcctcc cctttactac cggctgggtt gattgcctat
     4501 tccggcggaa gttcatcgcc gccgccggct atgttccatt cgacttcgac cggccggacg
     4561 ggaaactcaa agcgagattc gacctgggct ttcgaagaca cctctaccgg ttgccggatc
     4621 acatgaggct cgtcatacac aggcctggaa gcactgaact tgacgatatt gaagccgggg
     4681 tgccaggcga ccagcgtgta ggagccggga ggaatgcctg cgatctcgaa tttcccctgt
     4741 tcatcggtca cggcaaaata gggatgctcg agggctgccg cccacgcatt catatgcaca
     4801 tgcacatcac actgcagccg caagccgacc ccccgtgccc ggcccagcgt ggtcgcgatt
     4861 tcccggttcg ccgtgggcat cgcaatgttg aagaggcttt gtttctcgct gaagagatgt
     4921 ggattgtgga ggatcggttc gaaattgatg agcgccactt ccgccgtgcg gacgaaggga
     4981 atcatatgtc gttcgaactg gcaggcccgc cccgtgggat gcgaggcgct tttccccatg
     5041 cgcaacggat aggccgtggc tgcggacttc ccccgttcta cccgctcaag atagaccagg
     5101 acttcgtgaa tgccgttcgt ggccggatcg attcgcaaag ccggtgacgg cacgtgcgtg
     5161 ccgcaggagt ccagatccgc aaacactttg agcggcggca acttgggaat actgcccttc
     5221 cagaccgcct gacctttgac tgtgccgcca tcggagacgt cgatgatttc atattccgca
     5281 tatccgctga ttgcggtgag aagccaggcg aggcaggaga ggagcacaag gcggaaaccg
     5341 cgatgtcgtc gtggagacat gaaagacctc atcgacatac cgagagccgg atggcccagg
     5401 gcggtgaaaa taaaaaagcc cgaatctcca caggagattc gggctcgaga gctgatcgct
     5461 cgttggcctc acttatgtgc gcacggtggg gagcctaatc aaccctcctt cggcctgtca
     5521 agtatgcgat gccgcatgta acacaggcca tgcgttccgc tcactcactc cgcgagacct
     5581 cgcttcatca ggcaatccct cccagagacg ccgatctatt tgaatccgat gaccatggaa
     5641 tccggcccgg ccagcggttc aacctttgtg cgtgtgaagc cgaccttctt catccactgc
     5701 cggcaatccg caccggtgaa atcaaatccg cccggagtct cgatgagcat attgaggctc
     5761 atcaacaaac caaaggcatt cgttttcctg gcgtcatcga tcagggcctc atgaacgatc
     5821 aatgcgcctc ccggtggcag cgctgcatag gccttgcgca acagcatcat tttttctttg
     5881 aggtcccagt cgtgcaagat gtgccccatg atgagcacat ccaccttcgg cagcgagtcc
     5941 ttgaagaaat ctccctcgtg aaacgtcatg cgcttctgca gcttcttgct tctgatatag
     6001 gattcaaaga ccggccggac gacaggaaga tccatgccct ggccgttgag atgctggtgc
     6061 gccagcgcaa tctcaaccgc cacgccgcct tgagcacaac cgatgtcggc aaacgagtgg
     6121 tatcgtttcc agggaaattt cgcggcgatg gatcgggccg ttcccttgct gagtccggtc
     6181 atcgccttga ggaatccttc caatcgctgc ggatccgcgt acagcgtgcc gaaaaaatct
     6241 tcgccggttt tcacttcatt ctgcggttga ccggtacgca gcccctcggt cagtgatccc
     6301 caaaatccat acaggcgggc attacacatt tccagcatgc cgccgacata cgtcggtttg
     6361 gcccgatcga ggaacagcgc ggtctctggt gtgttggcat agcgtgtccc gttccgtttc
     6421 aggagcttaa gtgccaccaa cgcatcgaaa aagtctcgcg cacttcgcgg atgcagtttc
     6481 aatctggccg ccaaggcttt cccatcgagt tggcgcttgg ccaacagcgt gaagagtccc
     6541 agctccaccg ccgacaatag agtcttggaa ctccaaaacc cgaacccgat ttgcaggatg
     6601 tgatcaggaa ccaatggacg accggccata atgccatcct ttcgtgagaa aaattctcga
     6661 gaggctacgc gggaaatgtc gccctgtcaa tttcagctac cgctccacgg tcacggaccg
     6721 tatctctttt tcctacgccg tatcgagaga gatacagcgg ctcagattgc gcaggaatcg
     6781 ccacgccgtc acagcctacg cagagcgatg gatctgcaat tgggacgaca aggcaggatc
     6841 cttgctagag catcgcacat ctacttatcc gctcatgacg caaaaaggag atcctcgaca
     6901 tggctacgta cctccacgtg aaggcagccc tgacggcact cgtactgttc agcatcatga
     6961 cggcgaccgc cggtgcagag caatggaacg gaccgcaaac tcccacgggg accatctggc
     7021 gtccgggtaa catcgcactg gggtttgatc ccgccggtca cagcggcact cctccggcac
     7081 tcgaaatacg ccgccccctt tcaggcaccg aagaggtgct cctcagcttg cgttccacct
     7141 ttaaagaggc caccgctacc gtattggaag tcgacaccaa acgggtctac atgggcgggg
     7201 cggcgaccag aacctccctg atgccggatg gcgtattcga tctcgccgta ggacgcggca
     7261 tcgccgtggg ggtcaacagt gtcacggaac gactgccgac cgattatcga ttggtggtgg
     7321 gcgggaaggt gctggctgaa gaagtccgca tcaagctgat caaggactgg gcggactatg
     7381 tcttccatcc ggattaccga ctggcggcgc tccctgaagt ggccacatac atccagagcc
     7441 accagcatct gcctgacatg ccaagcgccg ccgaagtcgc agccaccgga atcagtctcg
     7501 gcgacatgca ggcgaaactg cttcgcaaga tcgaggaatt gacgctgcac gccatcgaac
     7561 aacaccagac catcgcagcg ctgcaggcgc ggttgcaaca gctggaggaa gaccggtcgt
     7621 cccagcagct agggagcaag tagccgcgat cgattcacat cgttaagagg gggcgcagcc
     7681 atgactcaat tcaccgcact cacaacggcg ttgctgctgg cgacattgac cctgccggcc
     7741 gaggccggga ctaccagcct cacgctgaac caagtcatca aggaaggcac cgctcgttac
     7801 tacgaccacc ctcaagagct gaggctggca gatgggtttt gggctcaggc cggttccgac
     7861 atgacagcca ccattcacct tcagcaggga tactacctgg ataagacccc cctggatacc
     7921 aaggagaagc aatacacgtc cactgacggc cggacatacc tggtcgccgg ctgcgtaccg
     7981 aaacacctcc ccatctcggg accggtcggg tcagtgtggg tggcgtgcaa cgacctcgat
     8041 tatctcaagg ataaggtcgt cgaaagccgt ttcgtgtcgt gtctggatgt gttcaccaac
     8101 ggcgtggtgt ccggcgtctc aatcaaggag gtcaacaatc ggacgtggga atcgttccgg
     8161 ttctcctgcc gcgacatggg gccagacggc agcatggtgg gcgccgctca gaaatccgac
     8221 ttcttattca actatgaacg cgaaggcaag ctgtacgaaa ccacgacggc cagcgggcac
     8281 ctcaccttcg gaatcctcga agtggccaac ggtctaaccg gcaccaagag cctgctccaa
     8341 atcgcccttg aacacactgc cgccgccgcg cttcaggctg ccggagtcaa tggacggcac
     8401 gtcgacgact tcacactcag cgacaaagtt ccggacgcct ttggattagg cggcatgctg
     8461 agggtcgatc actggaaatg tccgcccggc atggtgatca ccggtatggc cattggccat
     8521 aacccggata agaaaggcaa tgacacgaag ccagtgtaca ttctggccga atgccggaag
     8581 ctgctgtaca ccccataagg ccttacctta aagccgttgc acgacaggtg atctgacgct
     8641 tcacatccgc gtctgtttat ccacttccac ctcgttgtgc actacgagcc gctcccccaa
     8701 ctccgggcac gccggggatt cacctagtta cgacgtctcg ccatcccggc ttttaataga
     8761 ttatggctac aatgctccag aaggcgctgc aaggactcct gctcgtcctg ctggtgggct
     8821 gctcgacaac gtatgagccg catctcgtgc ttcctcctgc cgaattcaac cgctccatcg
     8881 atgcggccgt ggaagtgcat ccctttgtcg cagctgatga ccttctatac gggcgttcca
     8941 actatggcgt ggttgctgat gactatgcca ataagccccc ctcaaagttg acgcaatcga
     9001 ttacccagca agtgacggcg gaattggcgg cccatcgggt gtttcgccgg gtcagcacct
     9061 atgatccggc accggacctt atcctgacgg gtcgaatcga acggttcttc gaacacgacc
     9121 gccgtaaact atggacattt attccgtact attccgacaa actcgccagt cttttccgtg
     9181 tgaatagttt caagacgaat ggagaaattc atctcacact caccttgctg aaacccacgg
     9241 gagaagtggt gggatcgtat gtggggcatg cttcattcga cgaagattac acgcccaatg
     9301 gggaggtgcg tcccggcgat cgactcaatc gcgcattggg acaggctctc gcgcagattc
     9361 gtgatgagat gtttgcggac tcgaccttga cgaaatcacg tacaccccac ccgcttgcgc
     9421 ttcagtgatg cttcccctcg agtttgatga gaccgagcaa cccagaagat ccgcgcagtc
     9481 actgaccacg ctctcctaat ccccgcatct catccaacca gctcgcacgc cgttgctcat
     9541 tcatactttc gatattgccg atgagcgtgg ctctggtggg tttgatgcca cagcattgaa
     9601 tgatgttccg ctgcagaccc ttgaggctat ggacgtggta ccaccaccga tacacccatg
     9661 ccggcatgcc catcgtcacc acgacacgcg ccgactttcc ggcgaataac tttttggccc
     9721 tcgttgcatc gggttgatat tggaatgcca cacccgagcg gaacacctgt tcaaagaatg
     9781 ctttgagaag tgccggcatt gatcccagcc atagcgggca gacaatcacg agatgccccg
     9841 cccaacccat ggactcttct gcccgtctga tcgaatccgg cgcttgccct ttctcaaaat
     9901 cctcgtttgt tcgtaggaca ggaacgtcca acattgcgac ttcgacccgc cggactgtag
     9961 accaccgtcc tcgcactcct ttgcatattc gtcagccaat gcatggcaaa aatgacgagc
    10021 ctgtccgtca gggtgcccct ggataatggt aatgcgctta cccatggtga ggcgtgggtg
    10081 tcgcgcttcc ctctcgtacg atcggacgaa gggatcgatc catctcgcgg acggggccct
    10141 ctggtctttg ctcgatgctc tgcggggcta cagtcggcct ttgttgaatc ttgggtgtcg
    10201 gcggtgcaca agcggccata gagaagagca gtcccgtcac aatcacgaaa acgatactcg
    10261 ttatggctcg cattctcctt cctccctcac catcttcaat cctctgcccg acttcatcgt
    10321 tcctcgctag gcagcgatca acagtcctca cccagatgag cgcaacaggt atgccagaac
    10381 cgaggcatgg cgaagggcag caaatcgagc agaatggctc gatcacgagg ccatcgtgcg
    10441 atggcgctgc ggatattttc cgcagtacga ggaccaggag ctggcgcgaa tgtccacagc
    10501 agagaacatc cctgactccg gaagacggct gctgctttta ttttttgcga cggaggggga
    10561 gaatgagcag gggcatgcgc cgaaggctgg tgccctgtcg ccttattcca accgaacaga
    10621 aggagggtcc tatgagggca acagaatatt tcgctcgcgg gtgtgatccc aacacattag
    10681 tcgtcaggca aatcatggag gatgccgtcg tcacgattca ccccacatcg agcgccatgg
    10741 ccgtcgcaga aatcctgagc gaacacagct ttggaagtgt accggtggtc gacaaggacg
    10801 gaaccttgcg tggcctcgtg accgagtttg atctgctcaa agccgtcgag caggaacgag
    10861 atctccggag cgtgttggtg tcggacatta tgaccaaaga cgtggtgacg acgaccgaag
    10921 agacgccgat aatgagtctg attcatctgc tgcaggagag gcacctgatc cgagtgccgg
    10981 tcgtgaaggg gcagaaacta gtcggcatgg tggcacggcg agatgtcgtc tttgcctatg
    11041 tgaaagcccg ggcaatctac tggccgtaat gccgctctag gacagagcct ctcgaacggc
    11101 atggcgcttc acgcgccaca gccctaatgg gcgacgctcg gcgcagaacg gtgtgacggc
    11161 tgctgcacct gcgaattgcg aggcgcagat agtgcggcag tcataaccat ggtgactatg
    11221 gcgccaccaa aggccgcggc catgtccttc tgagcgtccc attcgtcgcc ctgcgttccc
    11281 agatacatac tgcccaattc cggactgacg atcatcgcta cgatcgcttc aatcacctca
    11341 aagaatgcgc tctgtgcaag aatgctgctt accggcatca cataggacca actcccctgc
    11401 actcccgcca gccgcaccag cacttcccgc aaaggataga ccagcaagag accatacgaa
    11461 aaatggacaa gtctatcgaa aggattccgg gttagtcccg caatgtcttt gagccagaaa
    11521 ccgaatggca cttctgcata ggtgtaatga gcaccgatgg catggagcac catgaatacg
    11581 gcgatgaggg agtaggacgt gagagaaaat gtaaaacggc ggtaggtcag gactagaatc
    11641 gcgacgagtc cgacggccaa taaattttct aacacccaat catggcgatt gaccgggttg
    11701 atggccagcc agatccagat gatgccataa cccaataaca annnnnnnnn nnnnnnnnnn
    11761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11821 nnnnnnnnnn nnnnnnnnnn nggtacagga gggacgtcca atcaaactcc cgaaaggatt
    11881 gaattactct actggatgat cttcggtcct gcaacagtcc tgccgggccg ttcgccccca
    11941 taacatagac tcgcagccgg ccctcttgca cttggagaag tacctagcac aagcgggcgt
    12001 gctgctctgt cgcacaaggc cacgttcaaa gaccgatggc gaggggcata tcgtgattcg
    12061 gggcacagct gatgcatctc gattggatca atgacggatg ttgctatgcc aatgcccctg
    12121 ctggatattc ggagcctgag cgtggtcgtc gatggacagg tgattctcga tcgactggac
    12181 ctcgcggttc aaggccggga aatccatgcc ctagtcggtg ccaacggctc gggcaaaacc
    12241 acccttgcct acgtcctgat gggttgtgaa gggtactcgc cgagtgcggg acatgtgcta
    12301 ttcaacggca tggaccttct gcgtctgaaa atgcatgaac gcgcccgatt aggattgacg
    12361 cttgcctggc aggagccggc tcgatttgaa ggcgtgacgg tgcgcgaata tctgagttta
    12421 ggcaaaccag aatgcgatcc cgaaccggct ttgaagcagg tcggtctgga tccagaccgt
    12481 tatctcacac ggcgaatgga taaggcactg agcgggggcg aacgtcaccg aatcgagctc
    12541 gcatcagtcc tctccatgaa accgaagttg gccattctcg acgagccggt ggcaggaatt
    12601 gatatgcttt ccatccatca cattatcgaa atcatccgcg ccctgaaggc aagcggcggc
    12661 tccgtcctcc tgatcacaca ccaggaagaa gtggtcctca ttgctgatcg agcctcccag
    12721 ctctgcggcg gacgcattat tttctcgggc agcccgagtg aagccgtcga tcatttccgc
    12781 gggcgcagct gtgtgcgatg cgatggagag gtctgcgggt atgtcagacc ttgaggaact
    12841 catgcgcgtc ttgcccaggg tgggcgctga gccgtcgatc ctcgacgaca caggcattgc
    12901 ccatgtcgtg gcccacgggc atcacatcct gagccatcga accgtcccgg gccttcgcgt
    12961 cgacattcaa gaaacgccgg aggccatcat cggcaagatc gtcgtcgaag caggtgtcac
    13021 catcgcccag cccgtccacc tgtgtttcgg cctcgctcat cccaccggga cacaacggat
    13081 cacaatggat atgcaggtga acgaaggggc gcaggtgcga gtgctctctc attgcctctt
    13141 tcccttcgtc caagacggcc agcatcgcat gcaagccgtg atgacaatca atcccggcgc
    13201 gtcactgacc tatactgagg ggcactacca tggtccctac ggtggcatgc aggtcttgcc
    13261 gcatgccacg atcaagatcg gcaaaggggc ccgttatttc tcggatttct ccttactctc
    13321 cggttcagtg gggaacctcg atatcaacta cctcgtcgaa gtggaagagg atggactcgc
    13381 cgaactcagc gccaaaatct tcgcgcacca gagggatcgt ctcacactaa aggaagccgt
    13441 catgctgcgc ggcgagcggt cacgaagtct gatcaaaacc cgtgtagtgc tggaggatga
    13501 tgccacggca gagatcaccg gcattactga agcctatgca aagggaactc gcggccacgt
    13561 agattgcatg gaagtcgtcc aaggcagagc tcacgccagc gcaatcccga tcgtcaaggt
    13621 ttttcacccg gaggcgaagg ttacacacga agcagcgatc ggcagcgtgg ataagaagga
    13681 gctcgaaaca ctgatggcgc gcggactgaa tccggagcaa gcggtcgaac tgatcgtaag
    13741 cggaatgctt cgctagcctc gacgtctcac gaacggtcgg actgtcttga tcaagcggaa
    13801 ggatcggggg ggcactccgg atcttcgatc actgctccgc attcgaggca tcgataacga
    13861 ggagggtcgt cgtcgtgctc cgagtggatg cgatcgatga gtcgcatgtg acggcaggtg
    13921 agggtccgtg tcatggtcgg atcaagttga ggactacgca taacgacctc cccggatcac
    13981 gcttgactat gtacctgaga aaatgcgccc caaccctagc agatttctca agacttgaca
    14041 cgacgaattt tccgcagatg gaagccagac atatgctgac acaataattg gtggccttat
    14101 ggctttcgcc gctacatata gagatcatta ttctctgcga gcggttcacg caaagggctg
    14161 ggaggaaaaa gcaggacatt tcgccatcaa agatgaggaa tcaggcgtgg ccgccggctc
    14221 acccgaagct ggaatgaagt gtcgtgcggc ttctgaaagc gagacacaca gaatcccttc
    14281 tttcaccgca gcacaaagaa atgtacgtag cctcttcaga aatgcctgct cgtccgctcg
    14341 agaacgcacg aatggtccgc agccttccaa gagcgctgaa gaatggaaaa caagattcag
    14401 ccattcatac tgttgatgcc gcatttgacg gacgagttgc atcattctgg caggagtctc
    14461 catctccgga gaaagccaca cctttcgcaa gagatgcaag cgcgacaaca atcctccgac
    14521 tctaaacctg ccaaatgggg cacggttgag ccggtctgcc aatgtagcgc aggcctgaaa
    14581 ctctccatgg agatacccga tcgtggccgg aatttccgcc agcacctcgt tcgaggagcg
    14641 gccggtgtgg acattcggcg caaatccata aggctgagga gaacagcagg agaagtccgg
    14701 accagccgtc tggacccacg aggtgtacgg agtgacagac gtatcgatac ggtatccaag
    14761 acgaaggaga ttgcgcgcca cctccgtgtc aaatccccaa cggccgcttc ggaacgccct
    14821 tggagatcga tcaacgttgt actgaatcgc ttcatgcaac cgctgcaatt tttcgtattg
    14881 cagggtcgcc gggagattgc agagcatact attgcgttta cttaacggtt ccttaaacgg
    14941 cggagtattc cacggatgac aatgcgcccc gatctcgcac tccccggctt ccactatttc
    15001 ccgaaggatg ccgacggcat aggagtcttg catcaccggg taggtcacca gatacgtcgg
    15061 gatgatgccg aactcattga ggagagcctg caatctcggc aagcggtata cattctgcgc
    15121 cgtggcctgg ccatgcggaa cgatccccca ttgatcctct tcgacatcga tcgtaacgac
    15181 cagtctcatt attcactcca acgcagtcgg caacagccgt acagttgctt tgttaccgca
    15241 gcagtatctt aagagcctgc tttgcaccat ctaacaacgt gaccgccgca ccagacgcac
    15301 tgcgattgta acagcgcgat gtcaccaacc ggcaaagacc ggttgaccat tcgagcttat
    15361 acggttgcga gccctgcaag agatccacca tctgagcacc atcgcaaagt gcctgctcaa
    15421 tgacccgatg caacaggagg aggcccggac tggctttcgg caggatgtcc ggatcgaacc
    15481 cgggcaaata aaagtaataa acgccttgat acagaaaccc atagacgcct gcgatgggcc
    15541 ggtcatccag caacaaaaga tcgatcctga ctcgcccccg ctcactcaat accctcacga
    15601 tatcccggtg aaaccgtcga gactgttcat tcgcaaatac gccaccgccc ggccgtgagc
    15661 tccaccgtcg ttggtgcagg gtgatgacgg actcgaaggc gatctcaaca tcggcagggc
    15721 tggtggcacg ggtaaattgc attcgccccg cctgctggag acacctcgtc tttcgttgaa
    15781 tggtgtatcg tcggttgcgt cccaggctgg ctcgatacgt ggggagatcg gccggcagcc
    15841 ggatgaccgg gcaacagctc gtcgtactca catcaccgac cttccctgcc ttggcgacta
    15901 atccgttcca cagatcgagc gtggaggatt cggcagataa gtctgacagc gtcagaagat
    15961 cccactcatc ccgagcgtca ccgaacaaat agtggtagag gctctggagc atcgcgagct
    16021 tgtgctgttc ctgcacaatg aggtcgagat atgaggaaca cacggcctcg ctccccaaca
    16081 atctcaattc tcgaaccgcg aacaccgcgt gtttcttggt gcgacggaga tacagtggcg
    16141 caatgccgac caatgtttcg tgctcgtcaa atgcgagaag aattcgcagc tgactgtcac
    16201 ccaaatagtg gagggtccag tagtacagcc attcccaggt gagaaacatg ctgtgtcccg
    16261 gcatcctgtc cagcaacgtc tcccacgctc cagccagccc cttgaactcc tcgggggtcg
    16321 tcaccacctg aatggtcagt cgacgccgct gcttcatggg agatactcgc gcaacaaagg
    16381 caaggccgag gcgacaaact cttcctgtgc tttccagggg tcatcgttct cccggcttcg
    16441 aggctcagcg gagaccagca ccagagcccc gtcggtccgc ccccgcagca aggcctgttt
    16501 aatcgtcgcc agtttagctt cgacccggtc cgtataactg ctgccgttga tgtgatacca
    16561 aaacagggac gggacgggac gaccacgctc gtcgaaaacg gttcgattca ccgcgatggc
    16621 atcttccctt ctccccaaca tggcagcgat cgcccccgta tgaagcggag ccgtctccat
    16681 gcccaccagc tctttcccct gacgttgcga cttcgtgtat gccacgtaca cattcactcg
    16741 ccgtccgtca gagtcgcgat acgtccgcat aagggaatca tcagcggcgg cgaggctcac
    16801 cggtgaggca ctgttcaggc ggtggtcgac cacccaatcc ccgacgacgc ccgggaatgt
    16861 cgccagctct ttcttgagtc ccgacgcccc gcgatcaagt ccatagagaa caagcgtcgc
    16921 aacggaaaga gtgacacaag ccagccacca ggcgcgattc gaggcatggc gatgagagac
    16981 tggctcagag aaacatttct tctcctcccc atggatagat ggccgcaacg gaacgtgctc
    17041 cagtctgccc aacaaccagg ctcccgcaaa caggaacgcg aaggcgaccc aatcgacaaa
    17101 caagccctgc agtatgtggt acggcccgtg aagatccttg cctcccgctt gagcatagac
    17161 gcccatgacg gtcaaacgca gccaattggc cataatggca attgcgaccg acgacaggag
    17221 cagggtgacg cgggcccacc aggtctgcaa ggtcagagcc gccagcggca atccgatcgc
    17281 cagcacggca atgagcaggc ccgccccgct gcattctcgg gcgacttcaa gagtgacggt
    17341 aggaagaatg atgtcgatgc tgttctccag aatcacgggg atgccgaggg cgcgcaacat
    17401 ggagacggac atatttgcag tgaggagttg aaatggccat acaagcggct ccgtcaggcc
    17461 atcgaggacc ggcgtcatga agatcaaata ggctagcgga aacgcgagtg ctctcaaata
    17521 ggcgaacccg caaagcagca acaccagtcc cgcgagaacc aggatcaacg cgacgcttcc
    17581 ggtggtgaga atgccggcga cttcgctcgc caggagtaag gcgatggcac ctaccagcca
    17641 cagcaagcct gcgcccagcg ccggttcaac cggaagctgc ttcagcgtgg gccactgtag
    17701 tctgacgaga tagagactga gcagagggac caggaaccca tgggaaaagc cgtaccggtt
    17761 ccaccacaag tccaggaggt cgtggagtac tggcgcacag agcaggagga gaggaaggca
    17821 gaggcctgtg attctccaca gggcggaata attgcggagc agatacgcag gtgtcctgga
    17881 gtgaacaccc gccgacgtcg ggcgggttcc tgtagcggaa ggagtgacga gagaattctc
    17941 cacgcgtcgg cctcactgat catcaccaca gcacagttaa ccaactactc atccatctta
    18001 tttgacgcca ccatccgcgc tgcttgctcg gcttccggaa aaccacccgg caatgacagg
    18061 gcggatttca gctcggacaa ggcctcggtc tgccgaccaa ttttggagag cgccaccgca
    18121 tggtggtaac ggacgacggg atgttgtggg agcgcggccg aagcttctgc caggtatgga
    18181 tacgccctat cgaaccggcc ctgcttgaaa tagatccagc ccagcgtatc tttaatcgcc
    18241 gggttggaag gagccaactc cagcgcatcc cgtgcaaacc cgagtgcatc gtcaagctcc
    18301 tgctggtcgc tcaggttcgc cgccagatta ttcgcggcaa ccacatcccg aggattgagc
    18361 tggaaggcgc gtttgtaatg gccattcgcc gcatcgactt gtcctcgacg ggccaacacc
    18421 atgccaagtg ccgtatgaat cgccgaattc gtctcgtcct ttttcaaagc actttgaaac
    18481 gccgacacgg ctgcaggcag cttattctgc agaagctgca cttgtccgag ttcgtagtgc
    18541 gccagcgcaa gatccggtgc cagatccacc gctttccgaa acgctttctg tgcctggtcg
    18601 attttgccct gagcgacgta cacgcgtccc gcgagtctcc atgtgtttgg atcgcgcgat
    18661 gttttggcca gatacgcccc gagcacgcga tctgcctgct gagactgctt cgaccccacg
    18721 agtgtgacca ggtagtcctg catgatcacc gggtcatcag gcgcatagac cagcgcttgc
    18781 gcaaagagct ccgcggcctc agccggcctt gcttgcagct ggcgaagcgc tgccatcttc
    18841 acatagccaa tcggttgtcc aggcagttgc ctgctgatgg cgccatacac ctcctcggcc
    18901 ctggcccagt tcttcccgaa cacgaacaca tcaccataca acacggcggc ttccaggctg
    18961 gcggggttca ctcgcaacgt ctgcgagact tccttctccg cctccttcgg cttctcttgt
    19021 gtgagataaa gacgcgcgag agccagatgc gcagtctggt tagagggatc acgcctgatc
    19081 gcctcgcgca gcgcttcttc tgcctggtcc atgcggcctt gggttgatct aatcaagcca
    19141 aggtacacat gaggcccgac gagagtcgta tcacgaccga tcgccgcttc gaacaggctg
    19201 gccgcttgga gcagatcacg ttccgcgaat gccacccgcc ccttgagata cagggcgacc
    19261 ggatcatgtt catcggctgc gagaatcgcc tgcaggagcg gtttcgcttc ggctacctca
    19321 ccaagggtca acttcagctc ggcgagggcc ttccgtgccc tctgagaatg cctgtcggca
    19381 atgagcgcgg acaattcgtg ttcggcatct tcccgaaggc cgagcatggc ataccgctcc
    19441 gcgagcacta gcttgatgga ttcctgatcc gaactcagct cgactgcctt gtgaaactcc
    19501 ttccgcccct cctccggagc accggtcgca aacagaaact gtccacgagc aatgcgagca
    19561 ccggcagatg caggatcagc cttgaccccg cggtcgtacc actcggccgc ctgctcgatg
    19621 tcttgttgtg caaaatggat attcgccagg gcgaggtggg ggcccaccat cttcggatcg
    19681 agtgtgaccg cctgcttcag gatcgcgatt gcatctgcat tccgctctgc tctcaaggcg
    19741 actgctgcgc gaagcaggta ccctgccggg tgttggggat tggccgacac cagctcttcg
    19801 gcgatcttgc ctacctcgtc cattttccct ccggccagat acagatcgcc gagggaccat
    19861 ttcgcctcga aatgcgacgg atcgagttgc accacccgac cgagcgcctg gtacgctgtg
    19921 gatgggtctc cgccctttaa cgccgccttc gcgagtttcc actggagaga aggattatcc
    19981 ggagcagccc gcacggcgtt cttaaactcg atcattgctt cgcggaactg ttcctgctgc
    20041 acatacccgt caccgcgcac ctcatgc
//
LOCUS       DAOQPD010000071        19976 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1334_length_19976_cov_23.576477, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000071 DAOQPD010000000
VERSION     DAOQPD010000071.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 19976)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 19976)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19976
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1334_length_19976_cov_23.576477"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..594)
                     /locus_tag="PK063_14480"
     CDS             complement(<1..594)
                     /locus_tag="PK063_14480"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98306.1"
                     /translation="MRCTIVPDSRFLSRFALLLLVASQTTLAHGAVEESLSTLHTYTP
                     AIRNDPSPFHCTDCWDLKPDQRPSLPQHQSQRYRRGHHERGLRPHKNPFAKKSHSFSR
                     GMRSLPRHALSMGGFERTVEGWQVRTVDGDTIRYGTDRIRIRGYNAPELSEPGGREAA
                     LRLEQLLHDGIINIIPHGHDVYGRTLADVFVNGHNVAD"
     gene            812..1045
                     /locus_tag="PK063_14485"
     CDS             812..1045
                     /locus_tag="PK063_14485"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98307.1"
                     /translation="MDMFGKVGLVEVPILIAPDQKAWMDRMIKEGKIAIPPGGTLEKG
                     SLYSMFVRMLLHNAMEEQKRQEALDMDDEDDDE"
     gene            complement(1170..2453)
                     /gene="hemL"
                     /locus_tag="PK063_14490"
     CDS             complement(1170..2453)
                     /gene="hemL"
                     /locus_tag="PK063_14490"
                     /EC_number="5.4.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0042286 - glutamate-1-semialdehyde
                     2,1-aminomutase activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="HMZ98308.1"
                     /translation="MKTQRSEQLFAEAQQIIPGGVNSPVRAFRSVGGQPRFIARAKGA
                     RLYDVDGNSYLDYVLSWGPMILGHAPATVTKAIQQAAANGTSYGAPTELEIQLATMIR
                     EALPSMEQVRLVSSGTEAVMSALRVARAYTKRDGILKFEGCYHGHSDYLLAKAGSGLT
                     TLGIPDCPGVPEDFTKHTLTAPYNDLVTAEKLIKKHHRQLACVIVEPIAGNMGVVPPS
                     PDFLEGLRKLTDAHGMLLIFDEVISGFRVQYGGAQTLYGIKPDLTILGKIIGGGLPVG
                     AYGGAKDIMKMIAPSGPVYQAGTLSGNPLAVTAGIETLKRLKKPGTYEQLEQRSVALS
                     EGLGKIASKAGVPLTQTRVASMMCAFFTQGPVVDWATAKKSDTKVYAKFFHHMLDAGV
                     YLAPSQFEAAFMSVAHTPRDIERTLNAAQAAFKTL"
     gene            3139..3381
                     /locus_tag="PK063_14495"
     CDS             3139..3381
                     /locus_tag="PK063_14495"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98309.1"
                     /translation="MRVLCAWCVRDGKPAFLREKLPLDDLSETHGLCEDHFTSLSRSV
                     KQVVTPQVWLLSRLNDLSWGLTRWIQRQMGRLLFLS"
     gene            complement(3424..3834)
                     /locus_tag="PK063_14500"
     CDS             complement(3424..3834)
                     /locus_tag="PK063_14500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidB family protein"
                     /protein_id="HMZ98310.1"
                     /translation="MGLFDQLGQAATGMLGQTGNNNPLIQAVVGLLAQNSHVGGLGGL
                     IQAFQKNGLGDIVNSWVGTGKNLPISPEQIHQGLGGDLLKQLASQAGLSTEAAGGQLA
                     NLLPGLIDKLTPGGKIPDSTLIEQGLTLLRGKLG"
     gene            complement(3867..4403)
                     /locus_tag="PK063_14505"
     CDS             complement(3867..4403)
                     /locus_tag="PK063_14505"
                     /inference="COORDINATES: protein motif:HMM:NF013500.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="barstar family protein"
                     /protein_id="HMZ98311.1"
                     /translation="MSITALQSIKKPWAHLLVHAEGEALDKLLSVPAQFVTKTVSGKK
                     CKTKAGLLDEFARVFSFPDYFGHNWDALEECLADLDWLPGKGYLVVVTDADQVLTKPD
                     EEDDFETFVEILSEAGEAWSLKESDDATGNGLPFHAVLAVQERHKRTRHNWFAPPLAM
                     ERKATKSGGSKGSKTSGR"
     gene            complement(4410..4871)
                     /locus_tag="PK063_14510"
     CDS             complement(4410..4871)
                     /locus_tag="PK063_14510"
                     /inference="COORDINATES: protein motif:HMM:NF012755.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004521 - endoribonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease domain-containing protein"
                     /protein_id="HMZ98312.1"
                     /translation="MSVSRVTRLVLWVCATLLLHLGVAFTADPGPALLHTPVPHLTPA
                     PPQTPPADDGAVRAGPGSKHNEVRDTIPSAARDTLKAIEARHGEPLPGYVGGRNFLNR
                     ERVLPRGRYREYDVHPKVPGKNRGAERIVINQFSGKAYYTADHYRSFVPMN"
     gene            complement(4965..7304)
                     /locus_tag="PK063_14515"
     CDS             complement(4965..7304)
                     /locus_tag="PK063_14515"
                     /inference="COORDINATES: protein motif:HMM:NF012585.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HMZ98313.1"
                     /translation="MSASDKQATEQLDFVTLEGLLTYGTALAQRSSSGRYALPPPPPP
                     SADRLQPAQAAVEGMRAFIQHVQKGLPSAEAYRAARQTLLAKTCGNDPVVFFAAWNLL
                     LARGELAPLYRAPIGATQKPAHRRPVAIVPRTQLTPQLAEGRIVLDLGDDRFWLLPRD
                     LGDRTLFLTMRHGVSEVESKTHRVGRRLANVLDTERGVPRADAVGAALARMVGVVGQQ
                     LGYLHLRNYLDPRTFLHLISHSPNTEQLCRRITKALLPDGADAVHPHIEPTLESQDFG
                     WVTGMEKQAELDAAAQAFGVDAKTAKRLIKHPFYSYPGGHSFFDLYVDVIDGLHRLGH
                     AHPGEVLCLYTHSSTLRALRIYLDPRPFREAFSEFGEYKEGQDNVVLLTLENGKLSGY
                     STAVGLIESDRVAREAWVTVERERTQRVTLKPGRIKRLIALVSGGDFGGGGAALKELR
                     VTGNRFGLDVFFVRHGFLGLANNWIDAVTEEDTRGMSSHASSPIGSSRFEDFKDEQVQ
                     RAAMRSLAPYLEDSALVVLGGDGSLRGARAIHETYGVQVVGIPGTIDNNIAGTTSLGF
                     HSAIALANQSIESLKATSAAMGSIFFVEVMGAGSGHLALACAYQARAEGILVNEHPDP
                     DTYIEDIVLGTLQRTLGVPNKSHIFVVAERTPHRHHREGGVHGLVDYVAQTIATWPQR
                     RDATGPYSLASATKATILGHTLRGAPPTPEDKMIAQHLAYETVRRLVEQPDTIVGCMV
                     AYHDSNRIETIPLHAVSPKPFDWELFTRMHVTELQHDRV"
     gene            7512..>7897
                     /locus_tag="PK063_14520"
     CDS             7512..>7897
                     /locus_tag="PK063_14520"
                     /inference="COORDINATES: protein motif:HMM:NF012449.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HMZ98314.1"
                     /translation="MRKAKIVCTIGPASDGVGVLEQLIQSGMNAARLNFSHGTHASHG
                     QAIKVIREAADRQGVAVAIIQDLQGPRIRVGEIDGTLELRAGQRVRLRTMTLRSGGQI
                     GARNVLPADSAQDIPVTYQALTRDIRP"
     assembly_gap    7898..7997
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <7998..9118
                     /gene="pyk"
                     /locus_tag="PK063_14525"
     CDS             <7998..9118
                     /gene="pyk"
                     /locus_tag="PK063_14525"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: protein motif:HMM:TIGR01064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HMZ98315.1"
                     /translation="SAQDIPVTYQALTRDIRPGAKILIDDGLVELTADRIIDGAVECT
                     VVAGGRVTSHKGMNLPGTIVSAPTLTDKDREDLRFGVAQGVDYIALSFVRGADDIRAA
                     KQLIAECGGDVPVIAKIERQEAVTDLDAILQQADGVMVARGDLGVELGPEAVPVLQKR
                     IIATANRHRRLVITATQMLESMTQHTRPTRAEASDVANAVFDGTDAVMLSAETAVGHY
                     PVEVVQVMDRIVRAAEVETGPAFVRRASPDNRHLTFEEAICLSASSAAAATGATAIVA
                     FSERGTTARLVSKQRPAAPIIGFTPFEPVRRQMALYWGVMPHTMPQIPTTDERVNEAE
                     RRLKADGLATAGQRIVILSGTRIGQPGGTNLMKLHEVG"
     gene            9123..9683
                     /locus_tag="PK063_14530"
     CDS             9123..9683
                     /locus_tag="PK063_14530"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98316.1"
                     /translation="MISLRGAIIGIMAGIVGLTAWASPGHAQSNAVSHSPAKVVEKYF
                     ALDNKGVRLDASSFESVAGYVDWKEEPAWGKVVVINGFTVPDDFRQWEIVNRLEVVVP
                     VEFRVLGIMYLDTAGFVPEPGTEQARVRLKVMNGRWKIMEPILPPHVGQKRMLNVVRQ
                     AMLEEKDGTRQASLAALQAELRKAKE"
     gene            9680..10330
                     /locus_tag="PK063_14535"
     CDS             9680..10330
                     /locus_tag="PK063_14535"
                     /inference="COORDINATES: protein motif:HMM:NF024811.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HMZ98317.1"
                     /translation="MTKKSEIDLLIFDLDGTLIESKWDIADSVNLTLRDLDLPERPEE
                     EIFGFVGDGVKKLLRLAVGEGNQDRFDQALRVFRGHYLEHCLDRTVFYPGIDRVLAHY
                     AAKSKAVATNKAIEYTNVILKGLGHHHFAYVVGGDNGFGLKPEPGMLVHVMEQLGVKK
                     DRTVLIGDSTNDINGGHNAGIRVCAVGYGMGNRQKMAACQPDWFIERPEELMELFI"
     gene            10327..11898
                     /locus_tag="PK063_14540"
     CDS             10327..11898
                     /locus_tag="PK063_14540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pitrilysin family protein"
                     /protein_id="HMZ98318.1"
                     /translation="MISITRARTIGVVILSGILAAAAPGYAESPSLADRVIEHKLANG
                     MTVLMVERHQAPIVSINMTFGVGGVNEQVGLTGLAHLYEHMAFKGTRTVGTRDYEREQ
                     AVLDELTVVGNELDHRERDEAARAQMEGKPHVASPEVQQLQRRFKELQEKAGEFVVGN
                     EMALLYQRHGGVGLNASTGKDITRYVISLPANRLPLWASLESDRMAHPVLREFYKERG
                     VVMEERRLRTDDSPNGLLYETFTSTAFQAHQYGVPTIGWGSDIMALTPAATEAFFKTY
                     YGPNNATVAIVGDIQPKEVIALIEQTFGKIPAAPPIPALVTEEPPQRGERRVEIEFDA
                     EPALAIGYHKPTIGHPDDFVFDVIDEVLTEGVTSRLYSTLVRDKRLAASVLSDTNYPG
                     VRAPNLFVIAATPLAPHTTAEVESAIYEELERLKTEPISAKEFERVLNGLDADLVRSL
                     RSNSGLASQLAFYQTVAGSWRYVLNARARIAAVTPADVQRVAAQYLTKPNRTVGVLVK
                     KAPDKKMAAVGEVAR"
     gene            11955..13382
                     /locus_tag="PK063_14545"
     CDS             11955..13382
                     /locus_tag="PK063_14545"
                     /inference="COORDINATES: protein motif:HMM:NF017044.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pitrilysin family protein"
                     /protein_id="HMZ98319.1"
                     /translation="MSCPVFVLLFLVQASLVMAGDLVLDNPRSMRFPTVEFNPPDAER
                     LVLDNGMVVYLLEDHELPLVTINATLKTGSWLDPADKVGLAGMTGAAMRTGGSASMSP
                     DEVDEELEQLAATISIGFSKESGSASLDVLKKDLKRGVQIFSDLLRRPAFEQSRVELA
                     KLQALEGIRRRQDSPGSIVGREFAKLLYGPTHPSARETSVRSIESITREDLVAFHQQT
                     VHPNGIILGVTGDFDKAGMLALLREAFGDWAKGTVPDVTIPAVAESEFKTGVVRFVNK
                     DTSQTHLRVGHLTVKETHPDYVAVAIANDILGGSSFRSRLFNDVRTKRGLAYSVGSGL
                     RASVYDEGVWLMRAETKLSSTQEVVNRFVANMERMRNEPVTDAELEEAKEAYVNSFVF
                     SFTSASSIVARLMDLEYDGLPKDWLQQIRDKVVKLTKEDIQRAAKMHFNPDRLRILAV
                     GSGDALSKVLASFGEVKEITLAPES"
     gene            13588..14424
                     /locus_tag="PK063_14550"
     CDS             13588..14424
                     /locus_tag="PK063_14550"
                     /inference="COORDINATES: protein motif:HMM:NF012955.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HMZ98320.1"
                     /translation="MPLEDELSDIIKKARTGQQRSVADVARAAGFPEADLAGLERGQP
                     ARNREQVQAVGRALGLRAEQLAQVVEGWTPEALPASTPHVDTILGSIGGYEVKGYIVH
                     DRGEAVIVDTGYNADAMLEMLSKRALRLRAICLTHGHSDHADGIDAILKAHPVPVYLG
                     PDDLDLLSWRPSQDVLHVPKEDGTLQVGGLRLRFMPTPGHTPGGVCYRLEQAGEPMCF
                     VGDTLFAGSIGRSNPAGLYQTHLASVRQRVLALPPDTRLFPGHGPATTVHEERLHNPF
                     AT"
     gene            14440..15399
                     /locus_tag="PK063_14555"
     CDS             14440..15399
                     /locus_tag="PK063_14555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HMZ98321.1"
                     /translation="MNRDESDQNRSSGELISPSFENAEEDEWVEEERPAFSAFVLPIM
                     LFALTLFTVLWAGAYQTNTNPLVGPWDFLVDDPGSLWRGIPFAATLLGILVTHELGHY
                     VLSRLHGVPTSLPLFVPGLPHFVGTFGAIIRMRAPLTDRRALFDIGVAGPIAGFVVAV
                     IALVIGLRLSTVVPIQGNYGMHLGEPLLLQFASWVVIGPLAPTADVILHPVGFAAWFG
                     LFITSLNLLPIGQLDGGHVAYALLGERQRSVAVALIPILMVFGWLGWKGWFLWVGLAG
                     MMGLAHPPVRNPGRDLGTARVLIGWLALFIFAVTFSWEPFILR"
     gene            15403..16125
                     /locus_tag="PK063_14560"
     CDS             15403..16125
                     /locus_tag="PK063_14560"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98322.1"
                     /translation="MHCPKCGWDQDEGTADCARCGIIFAKMHRSPAPPVMPRSPGQDS
                     TRPRVVEEWLLITEDSVNPFYFAGRVLVFLLLVSWGWRFITTPLETNYTGESFLHLIN
                     LPFHEAGHLIFMPFGRFMMILGGSLGQILMPLICLGTFLLKTRDPFGGSVALWWTAQN
                     FMDVAPYINDARAMDLILLGGFTGKEVDAHDWNNLLTMLGWLQYDHGLAKLAYGVGTV
                     LMLVSLLWGASLLRRQYRRLDW"
     gene            16216..16671
                     /locus_tag="PK063_14565"
     CDS             16216..16671
                     /locus_tag="PK063_14565"
                     /inference="COORDINATES: protein motif:HMM:NF019237.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1566 domain-containing protein"
                     /protein_id="HMZ98323.1"
                     /translation="MFASLIFLWAGVSLSAVHAEEAASRFTLVLNGEAVKDSASGLVW
                     EREPDYIFDVWDRSVARCATKTVGGTQGWRAPSIDEIKTLVDLDQQDPSLPAGHPFRN
                     IKSGIYWTATPHPKDEIVAWQQSFFSGQSVTDQKSGTRRLWCVLGDAGK"
     gene            16923..18947
                     /gene="hyfB"
                     /locus_tag="PK063_14570"
     CDS             16923..18947
                     /gene="hyfB"
                     /locus_tag="PK063_14570"
                     /inference="COORDINATES: protein motif:HMM:NF005086.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_process: GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit B"
                     /protein_id="HMZ98324.1"
                     /translation="MTTLLTVLLGCYLLGGLLPLCTSRPHLQNILAHSAAALAGGAGI
                     ALGLLGLVASQPLTISVPSNIPYLTFALRLDPLAAFFVLTISLIGMAASIYAYGYVRE
                     FTGRVSIGLLGSLLNGFLLSMTLVVLADNGFFFLIVWEVMSLLSYVLVVTEHERPGVR
                     EAGLFYLIMTHAGTAFIILTFLLFSQETGSFSFEAFRHPDQRLPDGLRSIAFFTALIG
                     FGAKAGIVPLHVWLPYAHPAAPSHISALMSGVMIKTAIYGLIRVYFDFLEGQFPWWWG
                     FTVLSIGAVSALLGVMYALMEHDLKSLLAFSSVENVGIILLGIGAGMIFHTYGLHELA
                     ALGLLAGLYHTINHAAFKGLLFLGAGSLLFVTHTRNIEEYGGLLRRMPWTGLCFLIGA
                     VSIVALPPTNGFVSEWLVFQSLFLSVQLPTLFLKLMLPIAAAILALTGALALACFAKA
                     FGLSFLAQPRSAHARHAVEVPVSMRIGMGLLASSCALFGLAPMLVVPLLDRVTTPLAG
                     VAISEKVLALDGWVVAPVTVEFSSISMPVLAALLVGAAGLGLAIARLLRKGVHARYSR
                     TWGCGLPLTPRMEYSATGFVQPIKQVFETIYQPTVKLEREFLEQSKYFIRHQRFHSSI
                     EPLFEKYAYRPIVNGLLAAAERLRVIQAGSLHLYLAYIFVTLVLLLLWAG"
     gene            19010..19966
                     /locus_tag="PK063_14575"
     CDS             19010..19966
                     /locus_tag="PK063_14575"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit H"
                     /protein_id="HMZ98325.1"
                     /translation="MQVISQIGFVFIQLIILLAFSPFIVGVIRKVNARLQCRRGASLL
                     QPYADLAKLFGKQPVISSTTSWIFTAAPYIVFASTVAAGLLMPVFISHTPLNFAGNII
                     ALVYLLALGTFFLILAGLDAGSAFGGMGSSREAIVVTLAEPAMILSILAIALTAGSTN
                     LSTIVHQSALLEGMVLAPPAHLMALAAMFIVTLAETGRVPVDNPATHLELTMIHEAML
                     LEYSGRYLALMEWAAGIKLLVFLTLLVNVFAPWGIATEATLSALATGVAVYVAKVTGL
                     AVIIGVIESMFAKLRLFRVPELLGSAFILALLALVFFYTLRG"
BASE COUNT         3811 a         5516 c         6192 g         4357 t
ORIGIN      
        1 gtccgccacg ttgtgtccat tcacaaagac atcggcgagg gtgcggccgt agacgtcgtg
       61 gccgtggggg atgatgttga tgatcccatc gtgcaatagc tgctccagcc gaagggccgc
      121 ttctcttccg cccggttcgg acaattccgg cgcgttgtag cctcggatgc gaatccggtc
      181 agtgccgtac cgaatggtat cgccatcgac cgtgcggact tgccagcctt ccacggttcg
      241 ctcgaaccct cccatcgaca gggcatggcg cggaagggat ctcattccgc gactgaagga
      301 atgcgatttt ttcgcgaagg ggttcttatg cgggcgaaga cctcgctcat gatgtccgcg
      361 tcgataccgt tgggattggt gttgaggaag cgaggggcgt tgatcgggct tcagatccca
      421 gcaatcggtg cagtgaaacg ggctcggatc attccggatc gcaggggtgt aggtgtgcaa
      481 tgttgacagg ctttcttcca ctgcgccgtg tgcgagcgtg gtctgagagg ccaccagcaa
      541 cagcagggcg aaccggctca aaaagcggga gtcgggtacg atggtgcagc gcatactgaa
      601 cgtcctccgt tggttcagct ctcgttagag cacgctccat gccatgagtc acggctgggc
      661 tcttcggttg acaagccgaa aaaccgcgtg ctcaaatgcc gacgcacgtc cgtcgtgacg
      721 cgggaagcgc agtgttgccg gaagagcggg tcagctcgcc gggtttccgc gagctacgaa
      781 caatgagtga gaattcacgg aggtttacat catggatatg tttggaaaag tggggctggt
      841 cgaggtgccg attttgatcg cgcccgatca aaaggcctgg atggatcgca tgatcaagga
      901 aggcaagatc gcgattcctc ccggcggaac cttggaaaaa ggttcgctgt attcaatgtt
      961 tgtccgcatg ctcctgcaca atgcgatgga agagcagaaa cggcaggaag cgttagatat
     1021 ggacgacgag gacgacgacg aatagacaag aatgctgaaa tcggtcttca gctgcgtatc
     1081 cgaatggatg catttcgtat cagtttcgat acgaaatgca tccgggaacc ggcttcacaa
     1141 agagcaactc ccgccatctt cacaccaggt cagagggttt taaacgcggc ttgagcggcg
     1201 ttgagtgtcc gttcaatgtc ccgcggagta tgggctaccg acatgaaggc ggcttcaaac
     1261 tgtgatggcg ccaggtagac ccctgcatcc agcatgtggt gaaagaattt cgcatagacc
     1321 ttcgtgtcgg atttcttggc agtcgcccag tccaccactg gtccctgagt aaagaacgcg
     1381 cacatcatgg aggcgacccg cgtctgagtc agcggaactc ccgctttgct cgcgattttt
     1441 cccaatcctt ccgacagcgc gaccgaccgt tgttcgagtt gttcgtaggt acccggtttc
     1501 ttcaaccgct tcagggtctc gatgcctgcc gtgacggcca agggatttcc tgacaacgtc
     1561 ccagcctgat agaccggacc ggacggggca atcatcttca tgatgtcctt tgcacccccg
     1621 taggctccca cgggcagtcc tccaccgatg attttcccta gaatcgtcag atcgggcttg
     1681 ataccgtaga gcgtttgcgc gccgccgtat tgaacccgga atcccgagat cacttcgtcg
     1741 aaaatcaaca gcatcccgtg ggcatcggtc agcttgcgca ggccttccag gaaatctggc
     1801 gaaggaggga ccacccccat gttgccggcg atcggctcga cgatgacgca ggccagctgc
     1861 cggtgatgct ttttgatcag cttctccgcc gtcaccaagt cgttatacgg ggcggtcaac
     1921 gtgtgttttg taaaatcttc cgggacccca ggacagtcgg ggatacccaa tgtggtcaga
     1981 ccagaaccgg ctttggctaa gaggtagtca ctgtggccgt ggtaacagcc ctcgaatttc
     2041 agaatgccgt cgcgtttggt ataggcgcga gcaacgcgga gggcgctcat caccgcctcg
     2101 gtccccgaac tcacgaggcg cacctgctcc attgagggca gggcctctcg aatcatcgtg
     2161 gccaattgaa tttccaattc cgtcggcgcg ccataactgg tgccgttggc ggcggcctgt
     2221 tgaatggctt ttgtcacggt ggccggcgca tggccgagaa tcatgggtcc ccaggagagc
     2281 acatagtcga gatagctgtt gccgtcgacg tcatacaggc gcgcgccttt ggcgcgggcg
     2341 atgaagcgag gttgtccgcc tactgagcga aaggctcgaa ccggactatt aacgcctccg
     2401 gggatgatct gctgtgcctc tgcaaaaagc tgttccgaac gttgtgtttt catgggcctc
     2461 tttcagcgag ggttgaattg gggcgcaacc taacatggga aattcaaaac ggtcaattga
     2521 tgcaccgctt ttccctgcgc cccggcagat gatccgatac agcttggtat ctgaatcgat
     2581 acaccagccg ggaggcttca tgaattcaat cagagtttct tttaaaaatc atggtttttc
     2641 ctggtgtcga ttggtggcgc gagttttgct gaacaccggg tgtcattgcg taggagaaca
     2701 tgatgaaagt gatttgctcc tggtgtgaaa gtgaagggcg accggctgtg gtgcgggaaa
     2761 aagctccttt ggccgatgga cgcgaaactc acggcatttg tgccagccat cttcagcaga
     2821 tgggaatcgg gcgggatccc ctggttcctt gctacgaaga gggatcgcgc caacggtatg
     2881 agcctgcggt gatccgccga cgatctgaag tagcgtctgc cttattgcaa tgatgagtgt
     2941 aagacctcgc ctttcggaag agacaaaaaa tgtcatttgt cgccatattg ccacacaatt
     3001 gtctgcagga atcttcccct tccgccaatc tctttcttct aaccctctga aaaattgatg
     3061 aaccgatagc ccatgcctcc tggtgcgggt tttgcgcctg cagggaggag tcggactgca
     3121 acgaatggag tgacgtcagt gagagtgctc tgcgcctggt gtgtgcgaga tggaaagccg
     3181 gcctttctcc gcgaaaagtt gccgctcgac gatctcagtg agacgcatgg gctgtgcgag
     3241 gatcatttca cctcgctgag ccggagcgtg aagcaagtcg tcacgccgca agtctggctg
     3301 ctctcgcgcc tgaacgatct gtcctgggga ctgacacggt ggatccagcg acagatggga
     3361 cggttgctct ttctctccta ggcatctgca cgccggttag ccagaatcag ccggccatcg
     3421 aatctacccg agttttcccc gcaacaacgt taacccctgt tcaatcaacg tcgagtccgg
     3481 aatctttcct ccaggtgtca gcttatcgat caaaccgggt agcagatttg ccaattgccc
     3541 gccggcggcc tctgtactga gacctgcttg ggacgccaat tgtttgagga ggtcgccacc
     3601 caatccctgg tggatctgtt ccggtgagat cggcagattc ttgcccgtgc cgacccagga
     3661 attcacgatg tctcccagtc cgtttttctg aaaggcttga ataagtccgc caagcccccc
     3721 tacatggctg ttctgcgcga gcaggccgac cacggcctgg attaatggat tgttattgcc
     3781 ggtctgtccc agcatccccg tcgccgcctg tccaagttga tcgaagagtc ccatcagtgc
     3841 ctccttacat cacgggaagg tgcggtctaa cgaccgctgg tttttgatcc cttggatccg
     3901 ccggatttcg tcgccttccg ctccatggct agaggcggtg cgaaccaatt atggcgggtc
     3961 cgtttgtgcc gctcctggac tgccagcacc gcatggaacg gtaggccgtt gccagtcgcg
     4021 tcgtcggatt ctttgaggct ccaggcctca ccggcttcgc tcagaatctc gacgaaggtt
     4081 tcaaagtcgt cttcctcgtc gggcttcgtc agcacctggt ctgcatccgt gaccacgacg
     4141 aggtagcctt tgccaggcag ccagtccagg tctgccaaac actcttccaa ggcatcccag
     4201 ttgtggccga agtagtcggg aaacgagaag acccgcgcga attcgtccaa gagcccggcc
     4261 ttggttttac attttttccc ggagacggtt ttggtgacaa actgggcggg gaccgacagc
     4321 aatttatcca gcgcctctcc ctcggcatgc accaggagat gggcccaagg tttcttgatc
     4381 gattgaagcg cagtaatcga catgtgtcct caattcatcg gcacaaatga acgatagtga
     4441 tcggcagtgt aataggcttt cccgctgaat tgattaatga cgatccgttc ggctccgcgg
     4501 tttttcccgg gcaccttcgg atgcacatca tattcgcgat aacggccgcg tggaagcacg
     4561 cgctctcgat tcagaaaatt gcgccctcca acgtaacccg gtaagggttc cccgtgtcgc
     4621 gcttcaatcg ctttgagggt gtcgcgtgca gccgaaggaa tggtatcgcg tacctcatta
     4681 tgcttgctgc cggggccagc gcgcacggcg ccgtcgtccg caggtggcgt ctgagggggt
     4741 gccggagtga gatgcggaac cggagtgtgg agaagtgcag ggccagggtc agccgtgaag
     4801 gcgacgccca ggtgcaagag caacgtcgcg caaacccaga ggacaagtcg tgtgacacgc
     4861 gagacagaca tggtgattca caactcgtga cagcaactgg aaagacccta acacgtcaca
     4921 taggagcggt caacgtggcc accgcacgac ggaagagcaa cccatcacac acggtcgtgc
     4981 tgcagctccg tgacgtgcat ccgggtaaac aattcccagt cgaacggctt gggcgacacg
     5041 gcatgcagtg gaatcgtttc gatccggttt gaatcgtgat aggccaccat acagccgacg
     5101 atggtgtccg gctgttcaac gagccggcga accgtttcgt aggcgagatg ttgcgcaatc
     5161 attttatctt ccggagtggg tggtgcgcct ctcagggtat ggccgagtat tgtggccttc
     5221 gtagccgagg ccagcgagta tgggcccgtt gcgtcacgac gctgaggcca tgtggcaata
     5281 gtctgtgcga cataatcgac cagcccgtgg acaccccctt cccggtgatg ccggtgaggg
     5341 gtccgttccg ccacgacaaa gatgtggctt ttgttcggca cccccaaggt gcgttgtaat
     5401 gtgccaagga caatgtcttc gatataggtg tcgggatcgg gatgctcatt gaccaggatt
     5461 ccttccgccc tggcttggta ggcgcaagcc aaggccagat gaccggaccc ggcacccatg
     5521 acctcgacga agaagatact gcccatggcg gcgctggtcg ctttcagcga ttcaatggat
     5581 tgattcgcga gggcgatggc tgaatggaat cccagcgagg tggtgccggc gatgttgttg
     5641 tcgatggtgc cggggatgcc gaccacctgc acgccatagg tctcatggat ggcccgcgcg
     5701 cccctcaggc tgccgtcccc tcctaagacc acgagcgccg agtcttcaag gtacggagcg
     5761 agggaccgca tcgctgcgcg ttgcacctgt tcgtctttga aatcctcgaa ccggctgctg
     5821 ccgatggggc tgctggcatg gctgctcatg ccgcgtgtat cttcttcggt gacggcatcg
     5881 atccaattgt tagccaggcc gagaaatcca tgccggacaa aaaagacgtc caggccgaag
     5941 cggttgccgg tgacgcgcaa ttccttcaag gccgcccccc cgccgccgaa atccccgcct
     6001 gacaccaggg cgatcagtcg tttgatgcgc ccgggtttaa gcgtcacgcg ctgagtgcgt
     6061 tcccgctcga ccgtcaccca ggcctcacgc gcaacccggt cgctttcaat cagcccaacg
     6121 gcggtcgaat agccggacag tttgccgttt tccaacgtga ggagcaccac gttgtcctgg
     6181 ccttctttgt attcgccgaa ttccgaaaag gcttcgcgga agggacgcgg atcgaggtaa
     6241 atgcgcagcg cgcgcagggt cgagctgtgt gtatagaggc agagcacttc tccgggatgg
     6301 gcatggccca gccggtgcag cccatcgatc acatccacgt agagatcaaa aaatgagtgc
     6361 ccgccggggt agctataaaa cggatgtttg atgagccgtt tggcggtctt cgcgtccacc
     6421 ccgaatgcct gtgccgccgc gtcgagctcc gcttgtttct ccatgccggt gacccacccg
     6481 aaatcttgcg attccagggt cggttcaatg tggggatgta cggcatctgc cccgtcgggg
     6541 agcaacgcct tggtgatgcg gcggcagagt tgctccgtat tcgggctgtg actgatgagg
     6601 tgaagaaacg tgcgcggatc gaggtaattc cgcaagtgca gatatcctaa ttgctggccg
     6661 accacgccca ccatgcgggc cagtgccgcg cccacggcat ccgctcgggg cacgccgcgt
     6721 tcggtatcga ggacgttggc cagtcgccgg cccacacgat gagttttgct ttcgacctca
     6781 gaaacaccgt gacgcatggt gagaaacaat gtgcggtcgc cgagatcgcg tggaagcaac
     6841 cagaaacgat catcaccgag atccagcacg atacgacctt cggccagctg cggagtcagt
     6901 tgcgtccgcg gcacgatggc caccggtcgg cggtgcgccg gtttctgggt cgcgccgatc
     6961 ggtgctcggt acagcggcgc aagttccccg cgtgcaagca gtagattcca ggcggcgaaa
     7021 aataccacgg ggtcatttcc gcacgtcttg gcgaggaggg tttgtcgcgc ggcgcgatag
     7081 gcttcggcgc taggcagacc cttttgaaca tgctggatga acgctctcat cccctcgacc
     7141 gccgcctgcg ccggctgcag tcgatcggct gacggcgggg gtgggggcgg taatgcgtac
     7201 cggccgctcg atgaacgttg cgcgagggct gttccgtagg tcagcaaccc ttccaacgtg
     7261 acaaaatcca attgctccgt tgcctgcttg tccgatgcgc tcatgatcgc ctcgtggtgt
     7321 gtggcttcgg aagaaatatt tcatgagtcc ggcctcgaga gtcctccgga cgccatgcag
     7381 atgttctttt gcggcatacg gacgggtttg ttagaatgac ccgttgccga ccgaatcagg
     7441 aacgtttcgc gcctcaccgc atacgtacaa gatggtgtgc cgggccgatc ttgtcaagac
     7501 agaagaacag catgcgaaaa gcgaaaatcg tctgcaccat cggccctgcg agcgatggcg
     7561 tgggcgtgct tgagcaactc atccagagcg gcatgaacgc ggcgcggctg aatttttccc
     7621 atggcacgca tgcctctcac ggtcaggcca tcaaggtcat ccgcgaggcc gctgaccgcc
     7681 agggcgtagc ggtggcgatc attcaggact tgcagggacc gcgcattcgc gtcggagaga
     7741 tcgacggaac attggaactg cgagccggcc aacgggtgcg gttgaggacg atgaccttgc
     7801 gatccggcgg acagatcggc gcgaggaacg tcttgcccgc cgacagcgcg caagacattc
     7861 ccgtgaccta tcaagccttg actagggaca ttcggccnnn nnnnnnnnnn nnnnnnnnnn
     7921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7981 nnnnnnnnnn nnnnnnnaca gcgcgcaaga cattcccgtg acctatcaag ccttgactag
     8041 ggacattcgg ccgggggcca aaatactgat agacgacggc ctcgtagaat tgacggctga
     8101 tcgcattatc gacggcgcag tggaatgcac ggtggtggcg ggcgggcgtg tcacgtccca
     8161 caagggcatg aacctcccag gcacgatcgt cagtgcgccg acgttgacgg acaaagaccg
     8221 tgaggactta cgattcggcg tggcacaggg cgtggattat atcgccctgt catttgtgcg
     8281 cggcgctgac gacatccgtg ctgccaaaca gttgattgct gagtgcggcg gggatgtgcc
     8341 ggtgattgcg aaaattgagc ggcaggaggc cgtgacggat ctggacgcta tcctccagca
     8401 ggcggacggg gtgatggtcg cgcgcggcga tttgggtgtc gagttggggc cggaagcggt
     8461 gccggtgttg cagaaacgca ttattgccac cgcgaatcgc catcgacggc tggtgatcac
     8521 cgccacgcaa atgttggagt cgatgacgca gcatacgcgg cccaccagag cggaagcgtc
     8581 ggatgtggcc aatgcggtgt tcgatggcac cgatgcggtg atgttatctg cggaaacagc
     8641 cgtcgggcac tatccagtgg aggtggtgca ggtgatggac cggatcgtac gggcggcgga
     8701 ggtcgaaacg ggtccggcat tcgtacggcg ggcatcgccg gataaccggc acctgacgtt
     8761 tgaggaggcg atctgtttgt ccgcatcgtc cgcggccgct gcgaccggtg ccacggccat
     8821 cgtggcgttc agcgagcgtg gcacgacagc ccggctggtt tcgaagcaac gtccggctgc
     8881 gccgatcatc ggcttcactc cgtttgagcc ggtccgccgg cagatggctc tctattgggg
     8941 ggtcatgccg cacaccatgc cgcagattcc caccaccgat gagcgagtca acgaggcgga
     9001 gcgacgcctg aaggccgatg gtctggctac ggcagggcaa cgcattgtca ttctttcagg
     9061 caccagaatc ggtcagccgg gcgggacgaa tctcatgaaa ctgcatgagg tgggttagcg
     9121 gtatgatatc tctgcgcggg gcgatcatcg gaatcatggc gggaatcgtc gggctgacgg
     9181 cctgggcctc gccagggcac gcgcaaagca atgcggtgtc gcattcaccg gccaaagtgg
     9241 tggagaaata ttttgccctc gacaacaagg gggtgcgcct cgacgccagt tccttcgaat
     9301 cggtggccgg ctatgtcgac tggaaggaag agccggcctg ggggaaagtg gtcgtcatca
     9361 atggcttcac ggtgccggat gatttccgcc aatgggaaat cgtgaaccgg ctggaagtgg
     9421 tggtgccggt ggaattccgc gtcctgggta tcatgtacct ggataccgcc gggttcgtgc
     9481 cggagccggg cacggagcag gcgcgagtgc ggctgaaggt catgaatggg cggtggaaaa
     9541 tcatggagcc gattctcccg cctcacgtcg gtcagaaacg catgctgaat gtcgtacgac
     9601 aggcgatgct ggaagaaaaa gacggaacga ggcaggcctc gctggcggcc ttgcaggcag
     9661 aattgcgaaa ggcaaaagaa tgacgaaaaa gtctgagatc gacttgctca tcttcgacct
     9721 ggacggcacc ctcatcgaat cgaaatggga catcgccgat agcgtcaatt tgacgttgcg
     9781 cgacctggat ttgccggaac ggccggagga ggaaattttc ggattcgtcg gcgacggcgt
     9841 gaagaagctg ctgcggctgg ctgtcgggga aggaaaccag gatcggttcg atcaagcact
     9901 ccgcgtcttc cgcgggcact atcttgaaca ttgcctggat cgcaccgtgt tttatcctgg
     9961 tatcgaccgg gtcctcgcgc attacgccgc caagtccaaa gccgtggcga ccaataaagc
    10021 catcgaatat accaatgtca ttttgaaagg gctgggccat catcacttcg cctacgtggt
    10081 cggcggcgac aatgggtttg gtctgaaacc ggagccgggc atgctggtgc acgtgatgga
    10141 acaactcggc gtgaagaagg atcgcacggt gctcatcggc gacagcacca atgacatcaa
    10201 tggcgggcac aatgcgggca ttcgggtctg tgcggtggga tatggcatgg gcaatcgtca
    10261 gaagatggcg gcttgccaac cggattggtt tattgaacga ccggaggaac tgatggagct
    10321 cttcatatga tcagcatcac acgagcgcgc acaatcggtg ttgtgatcct ctctggcatt
    10381 cttgcggcgg ctgcgccggg atacgcggag tcgccgagcc tggccgacag ggtcatcgaa
    10441 cataagctgg ctaatggcat gaccgtgctg atggtcgaac ggcatcaggc gccgatcgtc
    10501 agcatcaaca tgacgttcgg ggtcggcggc gtgaatgaac aggtggggtt gaccggcttg
    10561 gcccaccttt acgaacacat ggcgtttaag ggcacacgga cggtcggcac gcgagattat
    10621 gagcgggaac aggccgtgtt ggacgaactc accgtggtcg ggaatgagct tgaccatcgc
    10681 gagcgggacg aggccgctcg cgcacagatg gaaggcaagc cgcatgtggc atcgccagag
    10741 gtgcaacagc tgcagcgccg gttcaaggag ttgcaggaga aggcgggcga gtttgtcgtg
    10801 ggcaacgaaa tggcacttct ctatcaacgt catggtggag tcgggctgaa tgcgtcgacc
    10861 ggtaaggata tcacccgcta tgtgatcagc ctgcctgcca atcgcttgcc attgtgggcg
    10921 tcgctggaat ccgaccgcat ggcgcatccg gtgttacgtg aattctataa ggagcggggt
    10981 gtcgtcatgg aggagcgccg gctccggacc gacgacagtc ccaacggcct gctctacgag
    11041 acctttacct ccacggcctt ccaggcccat cagtatggtg tgccgacgat cggttggggc
    11101 tcggatatca tggccctcac cccggccgcg acggaagcct tcttcaaaac ctattacggc
    11161 ccgaacaatg cgacggttgc cattgtcggc gatatccagc cgaaagaggt cattgcgttg
    11221 atcgagcaga ccttcggcaa gatcccggcc gcgcctccca ttccggcctt ggtgaccgaa
    11281 gagccgccgc agcgcggcga gcgccgggtc gaaatcgaat tcgacgcgga accggcactg
    11341 gcgatcggat accacaaacc caccatcggc cacccggacg attttgtgtt cgatgtgatc
    11401 gatgaagtgc tgaccgaagg agtgacctct cgtctgtaca gcacgctggt gcgggataag
    11461 cggcttgcgg cgtcggtatt gtcggatacg aactacccgg gcgttcgtgc accgaatctg
    11521 ttcgtgattg cggcaacccc gttggcgccc catacgacgg cggaagtgga atcggcgatt
    11581 tatgaagaac tcgaacgatt gaagacggag ccgatctcgg ccaaagagtt cgagcgggtc
    11641 ctgaacggac ttgatgcgga tctggtgcga tcgttgcgct ccaatagcgg gctggcctcg
    11701 cagttggcgt tttatcagac ggtcgcaggc agctggcgct atgtgttgaa cgcgcgggcc
    11761 aggattgccg ccgtgacgcc agcggatgtg cagcgggtgg ctgctcaata tttgaccaaa
    11821 ccgaatcgga cggtgggggt cctggtgaaa aaagcgcctg ataaaaaaat ggctgccgtg
    11881 ggtgaggtgg ctcgatgagg cgcctcatgg gtgaactgga aaaaggaaag gtcatgagac
    11941 aagcagcgag atggatgtca tgtccggtgt tcgtgctctt gttcctcgtc caggcctctc
    12001 tcgtgatggc cggggacctg gtattggaca atcctcgttc catgcgattc ccgacggtgg
    12061 aattcaatcc gccggacgcg gagcgtctcg tgctggacaa cgggatggtg gtctacctcc
    12121 ttgaagatca tgaattgccg ctcgtgacga tcaacgcgac gctcaaaacc ggcagttggc
    12181 tggacccggc ggacaaggtt ggcctcgcgg ggatgaccgg cgcagcgatg cgcaccggcg
    12241 gatcggcctc gatgtcaccg gacgaggtcg atgaagagct ggaacagtta gcggctacca
    12301 tttctatcgg cttcagcaag gagtccggat ctgcctcgct cgatgtcctg aagaaagacc
    12361 tgaagcgcgg agtacagatt ttttccgacc tgttgcgccg gccggcgttt gaacagagcc
    12421 gggtggagtt ggcgaagttg caggcgctgg aagggatcag gcggcggcag gacagtcccg
    12481 gttcgatcgt gggccgtgag ttcgccaaac tgctctatgg gcccacccat ccgagcgcgc
    12541 gtgaaacgtc ggtgcgttcg atcgaatcca tcactcgcga agacctggtc gcgtttcatc
    12601 agcagaccgt tcatcccaac ggcatcattc ttggcgtgac cggcgatttc gacaaggccg
    12661 gcatgttggc cttgctgcgc gaagccttcg gggattgggc caaagggact gtgcctgatg
    12721 tcacgattcc ggctgtggcg gagtcggagt tcaaaaccgg ggtagtgcga ttcgtgaaca
    12781 aggatacgtc gcaaacccat ttgcgagtcg ggcatctgac ggtcaaagaa acccatcccg
    12841 attacgtggc ggtggccatc gccaacgaca ttctgggcgg cagttcattt cgcagccggc
    12901 tgtttaacga cgtgcgtacg aagcgcgggt tggcctattc ggtcggcagc ggcctgcgag
    12961 ccagtgtgta tgatgaaggc gtatggctga tgcgcgcaga gaccaaactt tcgtccacac
    13021 aggaggtggt gaatcgcttc gtggcgaata tggagcggat gcgtaatgag ccggtgacgg
    13081 atgcggagct ggaggaggcc aaagaagcct acgtgaattc gtttgtcttt tcgttcacca
    13141 gcgcgtccag cattgtcgcg cgcctgatgg atctcgaata tgacggctta ccgaaagact
    13201 ggctccagca gatacgggat aaggtggtga agctgactaa ggaagatatc caacgggcgg
    13261 cgaaaatgca ttttaatcca gaccggttgc ggattctggc ggtcggttcc ggagacgcct
    13321 tgtcgaaagt gctggccagt ttcggcgagg tgaaggagat tacgctggcg ccggaaagtt
    13381 gaggaaggga gcgcagacag gtcgaggcgt ctttttgctc gcgcaacgcg cggcataaga
    13441 atgccctcgt tggacgcgcg cagtgaaagc cgccccgccc tgtcgtgcgc tcggcgcatt
    13501 gatgtgagaa aagagattga tacaatttct gcagtgacgg ccgcgtggtc atatgtccaa
    13561 tccacatgaa actggataca atcggttatg cctcttgaag acgagttaag cgatatcatc
    13621 aagaaggccc gcacggggca gcagcgatcg gtagccgacg tggcccgggc cgccggtttt
    13681 ccggaggcgg acctggccgg actggaacgc ggccagcctg cgcgcaatcg agagcaggtg
    13741 caggcggtgg gccgtgcgct tgggcttcgc gcagaacagt tagcgcaggt ggtggaaggc
    13801 tggaccccag aggcccttcc ggcctccacg cctcacgtgg acaccattct gggttccatc
    13861 ggtggctatg aggtcaaagg ctatatcgtg catgatcgcg gtgaagcggt aatcgtcgat
    13921 actgggtaca acgccgacgc catgttggag atgctctcca agcgggcatt gcgccttcgg
    13981 gcgatttgcc tgacgcatgg gcattccgac catgccgatg ggatcgacgc cattctgaag
    14041 gctcatccgg tgcctgtcta tctcggtcct gacgatctcg atctcttgag ctggcgcccc
    14101 tcgcaagacg tgctgcacgt gcccaaggaa gacgggacgc tgcaggttgg cgggctgagg
    14161 ctgcggttca tgccgacgcc aggccatact ccgggcgggg tctgttatcg tctcgaacag
    14221 gcaggagagc cgatgtgttt tgttggcgat accctgtttg ccggttcgat cggccggtcg
    14281 aatccagccg gactgtatca gacacatctt gcttccgtcc gccagcgcgt gctggccctt
    14341 cctccggata cacggttgtt tcccgggcat ggaccggcca cgacggttca cgaagagcgt
    14401 cttcataatc cgttcgcgac gtaacaccag aggcctgtca tgaaccgaga cgagtcggat
    14461 cagaaccggt cttcgggtga actgatatcc ccttcgttcg agaacgccga ggaagacgaa
    14521 tgggtggagg aagagcgacc ggcattttcc gccttcgtgc ttcccatcat gttgtttgcc
    14581 ctcacgctgt ttaccgtcct ctgggccggt gcctatcaaa cgaacaccaa tcctttggtc
    14641 ggcccctggg attttcttgt cgacgacccc ggctcgttgt ggagaggtat tccctttgcg
    14701 gcgacgctgc taggcattct cgtcactcac gaactgggcc actatgtgtt atcgcgtctg
    14761 catggcgtgc cgacctccct gccgctgttc gtgccggggc tgccgcattt cgtgggcaca
    14821 ttcggggcga tcattcgcat gcgcgctccg ctgaccgatc ggcgagcgct ctttgatatc
    14881 ggggtggccg gaccgattgc cgggttcgtc gtcgcggtga tcgccttggt gatcgggctc
    14941 cggctttcga cagtggtgcc gattcaaggt aattacggca tgcaccttgg agagccgttg
    15001 ttgctacaat tcgcatcctg ggtcgtgatc ggccccttag cgccgaccgc ggatgtgatt
    15061 ctgcatccag tcggtttcgc cgcctggttc ggcctcttca ttacctcgct gaacctcttg
    15121 ccgatcggtc aactcgacgg cgggcacgtt gcctatgcgc tgctgggaga gcgtcagcgc
    15181 agtgtagcgg tcgctctgat tcctatcctc atggtcttcg gttggcttgg ctggaaaggg
    15241 tggttcttgt gggtggggtt ggctggcatg atgggtttgg cgcatccgcc ggtgcgaaat
    15301 cctggccgcg atttgggaac cgcccgtgta ctgatcggct ggcttgccct gttcattttt
    15361 gccgtgacct tctcttggga acccttcatc ctgcgctgat tgatgcactg tccaaaatgc
    15421 ggatgggatc aggacgaggg cactgcagac tgcgcccgct gcggcatcat tttcgcgaag
    15481 atgcatcgct cgccggctcc gccggtgatg ccccgcagtc cgggacagga ctcgactcgg
    15541 cctcgggtcg ttgaagaatg gctccttatc actgaggact cggtcaatcc attctacttt
    15601 gccggacgtg tgctggtctt tctgttgctg gtctcgtggg gctggcgatt catcaccacc
    15661 ccgctcgaga cgaattacac cggcgaatcc ttcctccacc tgatcaatct tccgttccat
    15721 gaagccgggc acctgatctt catgcccttc gggcgattca tgatgatcct cggcggcagt
    15781 ctgggccaga tcctcatgcc gctgatctgc ctgggcacat ttctgctgaa gacgcgtgat
    15841 cccttcggcg ggtcggtggc gctctggtgg acggcgcaaa acttcatgga cgtcgccccc
    15901 tatatcaacg atgctcgtgc aatggatctc attctgctcg gcgggtttac cggcaaagaa
    15961 gtggacgcgc atgactggaa caatctcctc accatgctgg ggtggctgca gtacgatcat
    16021 ggtttggcga agctagccta tggcgtcggc acagttctga tgctggtgtc gttgctctgg
    16081 ggcgcgtcgt tgctccgacg gcaatatcga cgactggact ggtagcccgc tgctgtttcg
    16141 caactcccgt tcttgaaaag ccccgagaca tcgggcacac tgccggccat gcctatcgtg
    16201 tggatgcgcg gccgagtgtt tgcttctctg atcttcctgt gggccggcgt gtcattgagt
    16261 gccgttcatg ctgaagaggc ggcctcgcga tttacgttgg tgctgaacgg agaggcagtg
    16321 aaagattcgg ccagcggcct ggtctgggag cgggagccgg attacatttt tgatgtgtgg
    16381 gaccgctccg ttgcgcgatg cgcgacgaaa accgttggtg gaacgcaggg ctggcgcgcg
    16441 ccgagcatcg acgaaatcaa gaccctggtc gatctcgatc agcaggatcc ctcgctaccg
    16501 gctggtcatc cctttcggaa tatcaagtct ggcatctatt ggaccgccac accccatccc
    16561 aaggatgaga tcgttgcctg gcagcagagt ttcttttccg gtcagtcagt gaccgatcag
    16621 aaatcgggca cgaggcgatt gtggtgcgtg ctcggagacg ccggcaaata acgcctctgc
    16681 tcgctcgaag tcagtgtctc ccttctctct acctcgacac attttcctac aactccttag
    16741 caagtcagtc gtactgcgcg gttccttcgc ggcgggtaca ttgcgcagcg accaagaagg
    16801 tgataaatga agaggtgata ccctgctcgt tccacttgta ctttgacaac tgcaagagct
    16861 gacgtgtctc ttgatgattc ggtgagcatc gcgatgctgc gtgcagtgag ggtagtgtcg
    16921 taatgaccac cctcctgacc gtccttctcg gctgttacct cctcgggggg ctgctcccac
    16981 tctgcacatc acgcccgcat ctccagaaca ttctggcgca tagtgctgcc gctttggccg
    17041 gcggggctgg gattgcgctg ggactcctcg ggcttgtggc ttcccaacca ctgacgattt
    17101 ccgttccctc caacattcct tacttaacgt ttgcgctgcg gctcgatccg ttggcggcgt
    17161 ttttcgtcct gaccatttca ctgatcggga tggctgcctc gatctatgca tatggctatg
    17221 tgcgcgagtt caccggccgc gtgtcgattg gcctgcttgg ctcgctgctc aatggatttc
    17281 tgctttccat gacgctggtg gtcctggccg acaacgggtt cttcttcctg atcgtctggg
    17341 aagtgatgtc cctgctctcg tacgtcctgg tggtgacgga gcatgaacgg cccggcgtgc
    17401 gtgaagccgg gttgttctat ctgatcatga cgcatgcggg gacggccttt atcattttga
    17461 cgtttctgct cttttctcaa gaaaccggct ccttctcctt cgaggcgttt cggcatccag
    17521 accagcggtt gccggacggc ctgcgatcga tcgcgttttt cacggcattg atcggattcg
    17581 gcgcgaaggc cggtattgtc ccgctgcacg tgtggttgcc ctacgcgcat ccggcggcgc
    17641 cgtctcacat ctcagcgttg atgtcaggcg tgatgatcaa gacggcgatc tatggattaa
    17701 tccgggtgta ctttgatttt ttggagggac agtttccctg gtggtggggt tttacggtgt
    17761 tgagcatcgg cgcggtgtct gcgctcctgg gcgttatgta cgcgctcatg gaacacgact
    17821 tgaaaagcct gctcgcattt tccagtgtag aaaacgtcgg gatcattctg ttgggtatcg
    17881 gcgcaggcat gatttttcac acctatggcc tgcacgaact ggccgcactc ggattgttgg
    17941 ccggactcta ccacaccatc aaccacgcgg ctttcaaagg gctcctgttc ctcggggccg
    18001 ggtcgttgct gttcgtgacg cacacgagaa atatcgaaga gtacggcggc ctgctcagac
    18061 ggatgccgtg gaccgggctc tgtttcctga ttggtgccgt gtcgattgtg gcgcttccgc
    18121 ccaccaacgg cttcgtcagt gaatggctgg tctttcagag cctctttctc agcgtgcaat
    18181 tgccgacgtt gtttctcaag ctgatgttgc ccatcgccgc tgcaatcctc gcgctcaccg
    18241 gcgcgctggc gttggcctgt ttcgcaaaag ccttcggcct atcttttctg gcgcagccgc
    18301 gcagcgccca tgcccggcat gccgttgaag tgccggtgtc gatgcgaatc ggaatgggcc
    18361 tgctggcgtc gagttgcgcc ctgtttgggt tagcgcccat gctcgtggtt cccttgttgg
    18421 atcgggtgac gacccccttg gcgggcgtgg cgatcagcga aaaagtgttg gcgctagacg
    18481 gctgggtggt tgctccagtg acggtggaat tctccagtat ttcgatgccg gtcctcgcgg
    18541 cattgctggt cggcgcggct gggttagggc tggcgatcgc ccggctgctg aggaaaggag
    18601 tgcatgcgcg gtactccagg acgtggggtt gtggccttcc gctcacgcca cgcatggaat
    18661 attcggcaac cggcttcgtg cagccgatca aacaagtgtt tgagacgatc tatcagccca
    18721 cggtgaagtt agagcgagag tttctggagc agtcgaagta cttcatccgg catcagcgat
    18781 tccacagtag tatcgaaccc ctgttcgaga agtatgcata tcgcccgatc gtcaacgggc
    18841 tgttggcggc cgcggagcgt ctacgcgtca tccaggcggg cagtctccat ctctacttgg
    18901 cctacatttt cgtgacgctg gtgctgttgt tgctctgggc cggatagggt cagacaggtc
    18961 atgaagttca cgctgcggac ccgtcagtga ataccagatg aggaacgacg tgcaggtgat
    19021 atcccagatc ggattcgtct tcatacagct catcatactg ctcgcatttt ctccgttcat
    19081 cgtaggagtg atccggaagg tcaacgcgcg tcttcaatgc cgccgtggtg cgagtctgtt
    19141 gcagccctat gccgatttgg ccaagttgtt cggcaaacaa ccggtgattt cctccaccac
    19201 ctcgtggatt tttacggccg cgccctacat cgtgtttgca tcgacagtgg cggccggcct
    19261 cctgatgccg gtgttcatct cccacacgcc gctcaacttc gccggcaaca tcattgcgtt
    19321 ggtgtaccta ttggccttgg ggacgttttt cttgattttg gcgggattgg atgccggatc
    19381 ggcgtttggc ggaatgggga gcagtcggga agccattgtg gtgaccctgg ccgaaccagc
    19441 gatgattctg tccattctgg ccattgcctt gacggctgga tccaccaatt tgagtacgat
    19501 cgtccatcag tcggcgttgc tggaaggcat ggtgctggcg ccgcccgcac acctcatggc
    19561 gctggccgcg atgtttatcg tgaccttggc ggagaccggg cgcgtgccgg tggacaatcc
    19621 ggcaacgcat ctggaactga cgatgattca tgaggccatg ctgctcgaat attcgggccg
    19681 gtacctggcg ttgatggaat gggccgcggg tatcaagctg ctggtgttcc tgacgttgct
    19741 cgtcaacgtg ttcgcgcctt gggggatcgc gacggaggcg acactatcag ccctggcgac
    19801 tggcgttgcg gtctatgtcg ccaaagtaac ggggttggcc gtcatcattg gcgtgattga
    19861 atcgatgttc gcgaagttgc ggctgtttcg tgtgccggaa ctgctcggtt ccgctttcat
    19921 tctggcgctg ctggccttgg tgttcttcta cacgttgcga gggtaaggcg atgtcg
//
LOCUS       DAOQPD010000072        19837 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1355_length_19837_cov_23.522950, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000072 DAOQPD010000000
VERSION     DAOQPD010000072.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 19837)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 19837)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19837
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1355_length_19837_cov_23.522950"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(412..488)
                     /locus_tag="PK063_14580"
     tRNA            complement(412..488)
                     /locus_tag="PK063_14580"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(452..454),aa:Arg,seq:tcg)
     gene            complement(573..1091)
                     /locus_tag="PK063_14585"
     CDS             complement(573..1091)
                     /locus_tag="PK063_14585"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HMZ98326.1"
                     /translation="MNLVLIGYRGTGKSTVGKVLARKLGRTVVSTDAEIVKRANLPVP
                     EIVKQFGWDHFRDMESTVCRDFAARDQLIIDTGGGAILRPENVAVLQKNGVLVWLTAT
                     VETITRRIGGDTQRPSLTGTKSFTDEIRDVLTERTPKYQAAAAHVISTDGVSTAEVAE
                     RILKLIPHEPGH"
     gene            complement(1158..2012)
                     /locus_tag="PK063_14590"
     CDS             complement(1158..2012)
                     /locus_tag="PK063_14590"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HMZ98327.1"
                     /translation="MDITPHTQWCGIIGNPVEHSLSPAIHNAAFQKMGLDLVYLAFRV
                     ESLGDALKGIRALGNARGFSVTIPHKVAAIPFLDEVEPTAKHIGAINTIVAEEGKLKG
                     YNTDASGALRALKEGGALLDGHRVLILGSGGAARAIAFALATGTGIAGLTILGIEDAE
                     RQKLVKDLRDKTGVPIEDGPLTLDMLRNWVPHVRTLIHCTPVGMSPKVGESCVPANLF
                     RPELTVMDIVYNPRETKLLQEAKAGGCRTISGLEMFLNQAVLQFELWTKQPAPVDIMR
                     HVLESRFV"
     gene            complement(2079..2840)
                     /locus_tag="PK063_14595"
     CDS             complement(2079..2840)
                     /locus_tag="PK063_14595"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF005559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HMZ98328.1"
                     /translation="MNRLQGKVAIITGGNAGIGEAIAKLFADEGAHVVVTGRRKEELD
                     RVVKGIGVNGGRALAVVGSVTDEAHVQDVVAQTTRTFGKVHILVNNAGIGDFGKRLHE
                     TDDATWAKVLDINLTGVFRMTRAAIPELIKAGGGSIVNISTVASLIGIRGLSAYAASK
                     GGLDALTRSVAVDYGQDNIRCNAVNPGLVDTPMAAPLMADPASLEPIMAQYAIRRPGK
                     PEEVAKMVLYLASDEAMWVTGQTFPIDGGMTISKG"
     gene            complement(2837..3724)
                     /locus_tag="PK063_14600"
     CDS             complement(2837..3724)
                     /locus_tag="PK063_14600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N1)-methyltransferase"
                     /protein_id="HMZ98329.1"
                     /translation="MSQLQNGERVHLVDKKGRQYALTLKAGDIYHFSGETIAHDELIG
                     KPDGSIVTLSKGKRFLALRPTFGEYVLKMPRGAQVLYPKDLSLIPMWADVYPGARVFE
                     AGTGSGALTMALLRAVGPTGLVVTYEARDDFARTALTNIERYMGPVSTLMPMRKNAYE
                     GIDLLEDGRPFDRLVLDLPEPWQVVPHAAKVLRSGGIYLSFVPTIPQVMQTVDALERT
                     SVFGNIETFETLLRTWSIQGRSVRPDHRMVAHSGFLTVARKVEEGWWSRPNRTVDTVD
                     TEDRADRDHQDQEQEDATA"
     gene            4010..5266
                     /locus_tag="PK063_14605"
     CDS             4010..5266
                     /locus_tag="PK063_14605"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HMZ98330.1"
                     /translation="MMKHAIAIQDDTDPTVTVEVDPDADDAEASTLLDSIAQGDQPEA
                     DTEEAAPEKSLRSASSPFLLESLYFRSFGERGLLEREEEIELAKKLDLGTRQIRQTLL
                     QAVKACAGLKRAEEAAEHIQTLQTVRRLSGLSATALNQADHALEHLLLDSTAGVKVPA
                     AVRKELEACLATLRSSRVTLETAKDELVRCNLRLVVNVAKHYTGRGLTLLDLVQEGNI
                     GLMKAAERYQHRKGFKFSTYATWWIRQGITRSLADQSRTIRIPVHQTEASNRILRASR
                     RLVQQLGRQPRLEEVASLMRMRPDRLHETMQAFQEPVALEHQVGDGGTELGELLPDQQ
                     AVPPDAHVNRTELTREMDRILGTLTPREQTVIRLRFGIGEDQARTLEQVGQHLSVTRE
                     RIRQIEAKALKKLKTPMVKEMFAALK"
     gene            5390..6466
                     /locus_tag="PK063_14610"
     CDS             5390..6466
                     /locus_tag="PK063_14610"
                     /inference="COORDINATES: protein motif:HMM:NF012318.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HMZ98331.1"
                     /translation="MVTGAHSPGAPSRRGLTSRSAWPVLFVFLCNLTLTAFGLVRQDA
                     AAAPLTELPVPAVVSKVRPSVVTVLTRGIPQGGSQHGAPSGSGSGIILDTNGYILTNN
                     HLVQGVTSVVVGLSTGRLTPGRVVARDFLLDLALIRITAPDLVPAEFSQRSTLEIGET
                     VIAIGNPLALKGGSTVTVGVISALDRSVLTPEGETLYDLLQTDAAINPGNSGGPLVDR
                     FGQVVGINVAIAPSAQAISYAIAIEAVTSHIESMMARGSVERPDLGLIPLTITPSVAA
                     SFDLESDRGILALQVDRAKAAGQAGLQSGDVVTAIDNRPLYNMGDFWHAIEHANGQMT
                     FQVATQGKAGTATIIIPRPSLPRP"
     gene            6470..7303
                     /gene="lipB"
                     /locus_tag="PK063_14615"
     CDS             6470..7303
                     /gene="lipB"
                     /locus_tag="PK063_14615"
                     /EC_number="2.3.1.181"
                     /inference="COORDINATES: protein motif:HMM:NF010925.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033819 - lipoyl(octanoyl) transferase
                     activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl(octanoyl) transferase LipB"
                     /protein_id="HMZ98332.1"
                     /translation="MSLDRLIHEGAAAPFAGHATAERVEGPRPATLVCGGTMAYDEAW
                     NLQRTCRAERAADRCHDLLLLIEHPSVYTLGRTTQDQHWPGEAQLSRETSIPVIRTER
                     GGSITYHGPGQLVGYPILRLSDYCAGPKAYVRMLEEVLITTLAESGITARRREGLPGV
                     WVGDDRPSKIASIGVRISHGITTHGFALNVCPDLEPFSHIVPCGISDCRVTSMSALMS
                     TTPDLRVVQQQLAALFAARFQLTWTESVALEQFAAVMEPPNRQLFPSSIPAPANPGGA
                     P"
     gene            7303..8559
                     /locus_tag="PK063_14620"
     CDS             7303..8559
                     /locus_tag="PK063_14620"
                     /EC_number="1.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Glu/Leu/Phe/Val dehydrogenase"
                     /protein_id="HMZ98333.1"
                     /translation="MTELNTHTFRLAVAQFNEAAEAMQLDTNLRERLKLPQRSLIVSV
                     PVRMDDGRVEVFTGYRVQHDTARGPSKGGIRYHPEVNLGEVAALSMWMTWKCALADLP
                     YGGAKGGVRVDPKQLSRAELQRLTRRYAAEIFPLIGPDKDVPAPDVGTDQQVMAWIMD
                     TYSQQVGYAVQGVVTGKPLSIGGSLGREEATGRGVVYVTLEALQHLKLDVAKATVAIQ
                     GFGNVGSHTARIMQQAGARVIAVSDVSGGLYNPKGLDIPDLLRRYHEHHEPLRDIKLG
                     EPLSNDALLQLDCTVLVPAALSEQITEANAAKLRCRILAEGANGPTTLEADRILTDKG
                     VFIIPDILANSGGVIVSYFEWVQDVQRFFWKAKDIQDRLQDIITSAFHRTLHFSLERR
                     TTMRMAALMSGIDKVAQAHLQRGLYP"
     gene            8592..8978
                     /locus_tag="PK063_14625"
     CDS             8592..8978
                     /locus_tag="PK063_14625"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98334.1"
                     /translation="MTRYILAAIAGIWMADGLALLSAPLLVIRRLQESLETAPNLLRW
                     QAIGIGLGLMLLLWSTPLPYQPLWWMTGGAMVIKSCFLTWGPTAWRTPLLSWCFTREA
                     VDYRFFGLWLCTLAVLLLHALGLLHG"
     gene            9017..9310
                     /locus_tag="PK063_14630"
     CDS             9017..9310
                     /locus_tag="PK063_14630"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98335.1"
                     /translation="MSHQSIASLWEEHSRDGWPQFSSPNEGQLMTLDTVIGGCAVFYL
                     DGQPEMDSHRLAILEDCVADLDGLLEDLSDESLGYFQRLRRLATALVDVGRQP"
     gene            complement(9369..9845)
                     /locus_tag="PK063_14635"
     CDS             complement(9369..9845)
                     /locus_tag="PK063_14635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group 1 truncated hemoglobin"
                     /protein_id="HMZ98336.1"
                     /translation="MVSKYGMGAMLLGALALCGGCADTGGGSQTSRAAAAAPAAKSLY
                     DRLGGKPAITAVVDQFVANVAADGRINNRFATTDIPKLKGHLVDQVCQATGGPCRYQG
                     REMKATHLGMQISSADFGALVQDLVAALDTFKVPAGEKGELLALLGSMKKDIVEVP"
     gene            10026..10964
                     /locus_tag="PK063_14640"
     CDS             10026..10964
                     /locus_tag="PK063_14640"
                     /inference="COORDINATES: protein motif:HMM:NF015431.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HMZ98337.1"
                     /translation="MELRQLEYFMAVATHQNFSRAAEHVHVSQPSLSIQIGGLEKELG
                     TRLFDRLGRKVVLTQAGELFQVHAERALREVEQAEQVVHELLGAKRGRLIVGTLSTVN
                     SYMIAPLVSRFKLRFPDIHLQVHAQPSSEIVNGLLANRLDIGICLLPLTHAHVTTIPL
                     FEERLALIAPASMNIGKRRARMQDLAQLPLVLMPADYCLRKMVESECAKAGVHPQVVL
                     EMTSPEGILQAVAEGTGATILPELYVKSRLPASQLQIIDLYDPTPRHTVGLAYLTKRH
                     RGQAAEEFAALCETTMRDLQSDSTQPPRNKRKGRAA"
     gene            11129..11680
                     /locus_tag="PK063_14645"
     CDS             11129..11680
                     /locus_tag="PK063_14645"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98338.1"
                     /translation="MGVKEAFMMQRTRTFTALMTMLGSLCLAAVVTAEPYELSKNDVT
                     DPKGVASQDVSLFGIKLGDDEAKALDGLVNEKIPGIKAEQEATFIFLLDQRKPTGPMA
                     GVRVQDGKVDLIFINNRFAFKTRGIFRNVLNSESPDDVRKILGKEDYGDENVMGAMLA
                     YDKQGFQVNYLGKDVNVEFSLPH"
     gene            complement(11844..12773)
                     /locus_tag="PK063_14650"
     CDS             complement(11844..12773)
                     /locus_tag="PK063_14650"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012970.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HMZ98339.1"
                     /translation="MNRSHRMLPVAVMVIPFLMGALWTGQALAIDNDVDDEVITVPYD
                     PRPVPSAKQAHHSLRWRHVPAHSILLKELKTGTTLYQFESEKRLSPASLTKIMSALVI
                     LEYGHLDDEVTVSPKAARAHKTHLRLRTGQIFRLEDLLKAMLIVSANDACLAASEHVG
                     GDEARFVDLMNAKAAALELHNTHFSNACGFDAPEHYSTAEDLAKLSEIALHHPVFKEL
                     VREEREIIMPINEHRAYVLRTTNRLLGRIPGVQGVKTGFTSKAGRCLIAKVSQDGSDL
                     LLVILNSKRRWNTATSLINYGLRLSDSRAALAR"
     gene            complement(12820..13008)
                     /locus_tag="PK063_14655"
     CDS             complement(12820..13008)
                     /locus_tag="PK063_14655"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98340.1"
                     /translation="MHCLKCKGFMMVERHYTLMNRRLYARCLNCGFWIDLADLLRFFH
                     KVIASSVRGTKVRETYTL"
     gene            complement(13087..13260)
                     /locus_tag="PK063_14660"
     CDS             complement(13087..13260)
                     /locus_tag="PK063_14660"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98341.1"
                     /translation="MGCLTTLAVLMVQGGVRDLVSGTNPMGSSGAILSFSTTIFGGGL
                     LAGCLALILNRLR"
     gene            complement(13429..14622)
                     /locus_tag="PK063_14665"
     CDS             complement(13429..14622)
                     /locus_tag="PK063_14665"
                     /inference="COORDINATES: protein motif:HMM:NF024907.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VCBS repeat-containing protein"
                     /protein_id="HMZ98342.1"
                     /translation="MTINTYANKRRAIGRVGLALIAGLPLLFACSKTDPYVPPDPFYY
                     FESYAVGKNPTTVTTADFNRDQITDLITTNISSNSISLLFGNGDGTFRDQVQVKVCQE
                     PRSLALNDFNHDDQLDVALACSGGDQISILFGRGNGKFDEGPQYPVHRAPVSISSQDV
                     NGDGHPDLAVALRNDKVKIFLGSARGEFRPGVQYEYGDTPTSVALKDLNQDGQPDLVV
                     TNGGPMLSAVSVWIGNGDGTFRDPKDYKTGRRPLGVSFADFNNDHLPDLLVINGEGDS
                     FTTFLGNGNGTFQPGKDSGADASPNFGVAHDFDGDHIDDVAIVNLQSTDLSILFGRGD
                     GTFHYPPRNYRTKNGPFAVASFQVSADNGEEPGLVTADNGAASVSVFLHHGRKGQIPP
                     NSKPE"
     gene            14871..15197
                     /locus_tag="PK063_14670"
     CDS             14871..15197
                     /locus_tag="PK063_14670"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98343.1"
                     /translation="MSKKVTIPLSMYGVAEVLKWCIDRNNGRVPGVDTEGFKRMQSLL
                     AEKPTSNDYLALDQFWKKQVALELTEDEVSTVDRCLYDIPNFDNEPLPQIRHKFWPQA
                     AGIAAH"
     gene            complement(15529..16491)
                     /locus_tag="PK063_14675"
     CDS             complement(15529..16491)
                     /locus_tag="PK063_14675"
                     /inference="COORDINATES: protein motif:HMM:NF019968.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PCP reductase family protein"
                     /protein_id="HMZ98344.1"
                     /translation="MRWSDGALKRMERAPMFLRGMVRRLAEKKARELGYAEITEEILE
                     QFKGQMMGTMGGEGGMAEAADQMAKGQLPWTAAAKERLAAVPEFMRGMIKQIADEIAR
                     KGGHMEVNVDLFEKVEALGEIHERETTPLEWTEGALALLQQKIKESPPIAMDFVSDMI
                     RHDTEEMAREKGLTRIDEQTAVQLWEAPQERVAWSDEAWKRLQTSPDFVRSGIRKAAE
                     RRARKLGLKEVDSEHLTTFRNQAMMKAVKRIRSFGYNELTFDAFDTALQKTKRLQGND
                     QAEKRLQEIRSHFSDPEVKKPEGGTLGADLMGRFRKFLKGEGSL"
     gene            complement(16538..16816)
                     /locus_tag="PK063_14680"
     CDS             complement(16538..16816)
                     /locus_tag="PK063_14680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HMZ98345.1"
                     /translation="MTKAQIIERVSEQVTTLTKRQAEIVVNTIFDCIRDSLRSGNKTE
                     IRGFGSFRLRARRMKEGRNPKTGATVAVPAKRVPFFKAGKELKELLNK"
     gene            complement(16892..17791)
                     /gene="sppA"
                     /locus_tag="PK063_14685"
     CDS             complement(16892..17791)
                     /gene="sppA"
                     /locus_tag="PK063_14685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HMZ98346.1"
                     /translation="MGPQADTAGKPQRSLLRRILWAIVIVGGALILLNALLPDLDFST
                     QDRVALIRIEGVILDAQATISELKQYSENPLVKAIVLRIDSPGGGVVPSQEIHDAVKR
                     VKNKSNKAVIASMGTVAASGGYYIAAATDRIIANPGSLTGSIGVIMEMANFEGLMKKV
                     GVEGVVIKSGRFKDVGSPLRKMSDEERKLLQSVMDDVHQQFIQAVADGRSLEVSDVEP
                     LADGRIYTGRQAKEARLIDELGDLDDAIHIAADIAGMEGEPKVVEPRKRFSFREIIES
                     RWSSVFPKLELNTGVKLKYLMAF"
     gene            complement(17807..19522)
                     /locus_tag="PK063_14690"
     CDS             complement(17807..19522)
                     /locus_tag="PK063_14690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HMZ98347.1"
                     /translation="MSTATPQSEPKLDHDALAAMYEETFRNFEEGTITEGMVVAIGKD
                     KVVVDIGYKSEGMIPADQFSQEELGQLKVGDRLQVYLEECEDADGNLVLSKEKADKMK
                     IWEELEKLHKEEKSIEGKIISRIKGGMMVDIGVKAFLPGSQIDLHPVRDLDGLVGKTF
                     PLKIIKINHRRGNVVVSRRVLLEETRDRRRQTTLSTLKEGQLIQGTVKNITDYGAFID
                     LGGIDGLLHITDMSWGRVGHPSELFQVSDKVEVTVLKYDRETGRISLGLKQKSADPWT
                     GVAAKYPVGTRVRGRVVSLTDYGAFVELEPGVEGLVHVSEMSWTHEVRHPSRVVSVGD
                     QVEAAVLNIDPGSRKISLGMKQTAPNPWDMIEAKYPAGTRIEGKVKSLTDFGAFVGLE
                     EGIDGLIHISDMSWTKHIKHPSELFKKGQKVDAVVIRIDKEKERLSLGYKQLSRDPWE
                     EQIPNKYRVGDSITGKVSKIADFGLFIELDGDVEGLIHISEVGLDANVRMEEKFKPSD
                     DVTAKIIKVDRDERKIALSLRDHQLDSDRRQVDEFHASQGGIDQTLGRAAKQSRKRNQ
                     SDSEA"
     gene            complement(19577..>19837)
                     /locus_tag="PK063_14695"
     CDS             complement(19577..>19837)
                     /locus_tag="PK063_14695"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98348.1"
                     /translation="GTFEVLPPGAKWPRFRRVTVTYGEPLDFSADAAQLEGKVFYQHV
                     SRTVMAKIAELGQVPNPGEGQAHAGLTHDREATPTAKSCNAE"
BASE COUNT         4012 a         6102 c         5527 g         4196 t
ORIGIN      
        1 ggcatgtgcc cttgagtgaa ggagccaaga ccattctgag gtcatttgac tcgttcctac
       61 ggtcggcttg ggtctttccg ggattaaagg acgtgactca cccgatggac agccgggctt
      121 tcctccgacg ttcgtttgag cctggcctgc gccgagcggg gatcacaggg gcatgctggc
      181 actcactccg gcataccgca gcgagccgcc gtgtcatggc aggggtcgat ctggtgtcgg
      241 tgaaggaaat cctcgggcat cgcgatattg agacgacgct ccggtatgcc caccttgccc
      301 caggacatct tcgggacgcg gtgaatcgag gcagcctggc tggaaccgtg accaaaaccg
      361 tgaccagcct ggaggggaaa acggaagaaa cgctgcaacc tattgattat ctggtgcgcc
      421 cggagggact tgaaccccca accctcggat ccgaagtccg atgctctatc caattgagct
      481 acgggcgcgc gcggcgatta aaaccatgtt actgagggga agtcaaggaa ggtgacgagg
      541 cacggctgat ttcagtcgca gcggtctccg actcaatggc ctggctcgtg cgggatcagt
      601 ttgagaatgc gttcggccac ttctgccgtg gagacgccgt cagtcgagat cacatgggcg
      661 gcggcagcct gatacttcgg ggtccgctcg gtcaggacgt cacggatttc gtcggtgaag
      721 gattttgtgc ctgtcaatga cggccgttgc gtatcgccac cgatccggcg tgtaatcgtt
      781 tcgacggtcg cagtaagcca gaccaacacg ccgttctttt gcagcactgc cacattctcc
      841 ggccgaagaa tggcaccgcc accggtatcg atgatcaact gatcccgtgc ggcaaaatcc
      901 cgacacacgg tcgactccat atcacgaaaa tggtcccacc cgaattgctt gacgatttcc
      961 ggcacaggga ggtttgcgcg cttgacgatc tcggcatctg tcgagacgac cgtgcggccg
     1021 agcttgcggg cgagaacttt gcccaccgta ctcttaccgg ttccgcgata tccgatcagg
     1081 acgagattca taggagtttc caagctggaa aggatgcggt cgccactgcg gatttggcgc
     1141 ggagaggggc tgattcgcta gacaaaccgc gactccaata catgccgcat aatatcgaca
     1201 ggcgccggct gtttcgtcca caactcgaat tgcagcacgg cttgattgag aaacatctcc
     1261 aacccggaaa tggtccggca tccgccggcc ttcgcttcct gaagcaactt ggtttcgcgc
     1321 gggttgtaga cgatatccat caccgtgagc tcaggtctga acagattggc cggcacgcac
     1381 gactccccga ccttggggga cataccgacc ggggtgcagt ggatcaacgt gcggacatgt
     1441 gggacccaat tccgaagcat gtccaatgtc agcggaccgt cctcgatggg gactccggtc
     1501 ttatcgcgca aatccttcac cagcttctgc cgctccgcgt cttcgatccc gagaatagtc
     1561 agccccgcga tgcctgttcc cgtggccagc gcaaacgcaa tggcgcgagc agctccgccc
     1621 gaacccagga ttaacactcg atggccgtcg agcagcgcgc cgccttcttt caatgcccgt
     1681 aacgctcccg acgcatccgt gttgtaccct ttgagctttc cctcttccgc gacgatggtg
     1741 ttgatggcgc caatgtgctt ggccgtaggc tccacctcat cgaggaacgg aatggccgcc
     1801 accttgtgcg gaatggttac gctgaatccc cgtgcattcc ccaaggctcg tatgcctttc
     1861 aatgcgtcac cgagggattc cacgcggaag gccagataga cgagatccag ccccattttc
     1921 tgaaaggcgg cattatggat cgccggcgac agcgaatgct cgacggggtt gccaatgatg
     1981 ccgcaccatt gagtgtgagg tgtgatgtcc atacgtgatg atcctgcttc gtacaacgat
     2041 gatgcccacg actttgcccg actcgggaga ctgctacctt agcctttgct gatcgtcatg
     2101 cccccatcga tcgggaaggt ctgaccggtc acccacatcg cttcatcgga agcgaggtac
     2161 agcaccatct tggcgacttc ctcgggcttc cccggccgac ggatggcata ttgggccatg
     2221 atgggttcca aactggcagg atccgccatc aacggcgccg ccatcggcgt gtcgaccaac
     2281 ccggggttca ccgcattgca gcggatattg tcctgcccgt aatccaccgc caccgacctg
     2341 gtcaatgcat ccaagccgcc tttggatgcg gcataggccg acagtccccg aatgccgatc
     2401 agactggcca cggtagagat attcacgatc gacccgccac cggccttgat caattccggg
     2461 atcgccgctc gcgtcatccg gaacacgccc gtcaaattga tgtccaacac tttcgcccag
     2521 gtggcgtcgt ccgtctcatg aagtcgcttg ccgaaatcgc cgatgccggc attgtttacc
     2581 agaatgtgca ccttcccgaa cgtcctggtg gtctgcgcga ccacgtcctg gacatgggct
     2641 tcatccgtga cggagccgac gacggccagc gctcgtccgc cgttcacccc gatacctttc
     2701 acgacacggt cgagttcctc tttccggcga ccggtgacga cgacgtgcgc cccttcatcc
     2761 gcaaacaatt tggcaatggc ctcgccgatt cctgcattgc caccggtaat gatggccact
     2821 ttcccttgta accgattcat gccgttgcgt cctcctgctc ctggtcctga tggtccctgt
     2881 cagcccggtc ctccgtgtcg actgtgtcga cggtcctgtt cggacgggac caccagccct
     2941 cctcgacctt tcttgccacg gtcaaaaacc ctgagtgcgc caccatccga tggtcggggc
     3001 ggacgctacg tccctggatc gaccaggtgc gcagcaacgt ctcaaaagtt tcgatgttac
     3061 caaacaccga cgtgcgttcc agcgcgtcaa cagtttgcat gacttgcggg atggtgggca
     3121 cgaagctcaa ataaatgcca ccggagcgca agaccttcgc cgcatgcggg acgacctgcc
     3181 agggttcggg caaatccaac acaaggcgat cgaacgggcg gccgtcttcg agaaggtcaa
     3241 tgccctcata ggcattcttt cgcataggca tcagggtgga caccggcccc atgtagcgtt
     3301 cgatattcgt gagggccgtg cgggcaaagt catcacgggc ttcataggtc acgaccagcc
     3361 cggtcggccc cacggcgcgc aacaaggcca tcgtgagcgc gccggaaccg gttccggctt
     3421 cgaacacccg cgcgccggga tacacatccg cccacatggg aatcaacgat agatccttgg
     3481 gatacaatac ctgcgccccg cggggcattt tgaggacgta ctcgccgaag gtcggccgca
     3541 aggcgaggaa gcgtttgcct ttcgagaggg tgacgatcga tccgtcaggc ttcccgatta
     3601 actcgtcgtg cgcaatcgtc tccccgctga agtgatagat atccccggct ttcaaggtca
     3661 gggcgtactg acggcccttt ttgtcgacca gatgaacacg ttctccgttt tgtagttgtg
     3721 acataggtcg gcattctagg agatggccga cgcgttttca accgaacccc cgtcgaatca
     3781 gcgcttaaga ctctgtccgg ccgatccctt gacagttcag cgagcgtccc tatctcaatt
     3841 agacagaaat ctgaacagcc tcgtgctctc gtagtatcac caaggacagc cggacaatga
     3901 gagacgacac gaatcctttt tcctgttctg gtctcttaca gagatgaggg catctttccc
     3961 aagggttccc gtagccaacc atccccagga cggggaagag gggtgacaca tgatgaaaca
     4021 cgcgatcgcg attcaagacg atacagatcc aacggtgacc gtggaagtcg atccggacgc
     4081 cgacgatgcg gaagccagta cgctgctgga cagcatcgcc cagggcgacc agcctgaggc
     4141 ggacaccgag gaagcggctc ccgaaaaatc attgcgttcg gcttcctccc cttttctttt
     4201 ggaatcttta tactttcgtt cattcggcga gcggggactg ctggagcggg aagaggaaat
     4261 tgaactggcc aagaaactcg acctcggcac gcgccagatt cgccagacac tgctgcaggc
     4321 ggtgaaagcc tgtgcgggat tgaaacgtgc tgaagaggct gccgaacaca ttcagacgtt
     4381 gcagacggta cgtcggctca gcggcttatc ggccacggcg ctcaatcaag cagatcacgc
     4441 gctggaacac ctgctgctag acagcacagc cggagtcaaa gttccggcag cggtacgaaa
     4501 agagctggag gcctgcctgg ccaccttgcg cagttcacgc gtcacgctgg aaacggcgaa
     4561 agacgagctg gtgcgctgca accttcggct ggttgtcaat gtcgcaaagc attacaccgg
     4621 gcgagggctc actttgctgg acctggtgca ggaaggcaat atcggcctga tgaaggccgc
     4681 cgagcgctat cagcatcgta aggggttcaa attcagcacc tatgccacgt ggtggatccg
     4741 gcaaggcatt acacgttctc tggccgatca atcgcgcacc atcagaatcc cggtgcatca
     4801 gacagaagcg tcgaatcgca tcctccgggc gtcgcgccgc ctcgtgcagc aattgggtcg
     4861 tcagccgcgg ctggaagaag tggcatcgct gatgcggatg cggcccgatc gtctgcatga
     4921 aacgatgcag gcgtttcagg aaccggtggc actggagcat caggtcggcg atggcggaac
     4981 ggaactcggg gaacttctgc cggaccagca ggcggtcccg cccgatgccc acgtgaatcg
     5041 cacggaactc acccgcgaga tggaccgcat tctcgggaca ctcacaccca gagagcaaac
     5101 ggtcatccgg ttgcgattcg gcatcggcga agatcaagca cggacgctcg agcaggtggg
     5161 ccaacatctg tcggtcacgc gtgaacggat tcgacagatc gaggccaaag cgttgaagaa
     5221 gctcaagacc cccatggtca aggagatgtt tgccgcgctg aagtagcgac ggtacgacgc
     5281 cacgggagcg cgagacgggc gaggcctcgg cctcgcccgt tttgttttcc gggcgctttc
     5341 gccgcacggg cgagtgtgag agaatgcggc ggcggaggat cagctttcca tggtgacagg
     5401 cgcccacagt cccggtgcac catccagacg cggtctcact tctcgatctg cctggcccgt
     5461 tctcttcgtc tttctgtgta atctcacgct gacggcattc gggctagtgc gccaggacgc
     5521 cgctgccgcc ccgctgaccg aactcccggt acccgccgtc gtgtcgaaag tacggccctc
     5581 ggtagtgacc gtactgacac gcggcatccc gcagggcggt tcgcaacatg gcgcgccttc
     5641 gggatccggt tccgggatca ttctcgacac caacggctat atcctgacca ataatcacct
     5701 cgttcaaggc gtgaccagtg tcgtggttgg attatctacg ggccggctga cccccggacg
     5761 tgtcgtcgcc cgtgattttc tcctggacct cgccctcatc aggatcaccg cgcccgatct
     5821 cgtccctgcc gaattcagcc agcgctccac cctggagatt ggagaaacgg tcatcgccat
     5881 cggcaacccg ctggcgttga agggaggctc caccgtgacc gtcggtgtga tcagtgcgct
     5941 ggaccgctct gttctgacac cggaaggaga gaccctctac gatttgctgc aaacggatgc
     6001 cgccatcaat ccggggaata gcggtggacc gctggtcgat cgcttcggcc aggtcgtcgg
     6061 catcaatgtc gctattgccc cgtcggccca agccatcagt tatgctatcg ccatcgaggc
     6121 tgtgacctcg catatcgaat caatgatggc ccgtggatcc gttgaacggc ctgacctcgg
     6181 actaattccc ctgaccatca cgcccagtgt ggccgcaagc tttgatctgg aaagcgaccg
     6241 cggcatcctc gccctgcagg tggaccgcgc gaaagcagcc ggccaagccg gattgcagtc
     6301 cggggatgtg gtgacggcca ttgataaccg tccgctctac aatatgggag acttctggca
     6361 tgccatcgag cacgccaacg ggcagatgac gttccaggtc gcgacacaag gcaaagccgg
     6421 aacggctacg atcatcattc cacgccccag cctgccacgg ccgtaagcca tgagcctcga
     6481 tcgtctcatc catgaaggag ctgccgcacc gttcgcaggc catgcgaccg ccgaacgcgt
     6541 cgagggacca cgacccgcga cgttagtatg cggcgggacg atggcgtatg acgaagcgtg
     6601 gaacctgcaa cgcacctgtc gggccgaacg agcggcagac cgctgtcacg acctgctgct
     6661 cctgatcgaa cacccttccg tgtataccct gggccgcacc acgcaggacc agcattggcc
     6721 gggagaagcg cagctgtccc gggagaccag catccccgtc atccggacag agcgcggcgg
     6781 ctcgattacg taccacgggc caggacagct ggtcggctat cccatcctcc gactgagtga
     6841 ttactgtgcg gggccgaaag cctacgttcg catgcttgaa gaggtgttga ttaccacgct
     6901 cgccgagtcg ggtatcaccg ctcgtcgacg tgaaggcctg ccgggggtct gggtcggcga
     6961 cgaccgcccc tctaaaatcg cgtcaatcgg cgtgcgtatc tcccacggca ttaccacgca
     7021 cggcttcgcc ttgaatgtct gccctgacct tgagcctttt tcccacatcg tgccttgcgg
     7081 gatttccgat tgccgggtca catccatgtc ggccctcatg agcaccacgc ccgatctccg
     7141 tgtcgtgcag caacagcttg ccgcgctctt tgccgcacgg tttcagctca cgtggacgga
     7201 gtccgtggcg cttgaacagt tcgcggctgt gatggaacct ccgaaccgtc aactgttccc
     7261 ttcatccatt cctgcgccag ccaaccctgg aggagcgccc tgatgactga actgaatacc
     7321 cacaccttcc gtttggccgt cgcccaattc aatgaagcgg ccgaagcaat gcagctggat
     7381 accaacctgc gcgagcggct gaaacttccg caacgctcgt tgattgtcag cgtgccggtc
     7441 cggatggacg atggccgcgt tgaagtcttc acgggatacc gggtccagca cgatacggct
     7501 cgcggcccgt cgaaaggcgg catccggtac catccggagg taaacttggg cgaagtcgcg
     7561 gccctttcca tgtggatgac ctggaaatgc gccttggccg acctgcccta cggcggggcg
     7621 aaaggcggcg tgagagtaga tcccaaacaa ttgagccgtg cggaactcca acgcctcacc
     7681 cggcgctacg ccgcagagat tttccccctc atcggaccgg ataaggacgt gcctgcgcct
     7741 gatgtcggga ccgatcagca ggtgatggcc tggatcatgg acacctatag ccaacaagtc
     7801 ggctatgcgg tgcaaggcgt cgtcaccgga aagccgttgt ccatcggagg cagtctcgga
     7861 cgagaagaag ccaccggtcg tggtgtggtc tatgtgaccc tggaagcgct ccaacacctg
     7921 aaactcgacg ttgcaaaagc gacggtcgcc atccaggggt tcggcaacgt cggctcccat
     7981 accgcgcgca tcatgcaaca ggccggcgca cgggtgattg ccgtgagcga cgtgagcggc
     8041 gggctctata accccaaggg cctcgacatt ccggacctct tgcgtcggta ccacgaacac
     8101 cacgagccgc tacgcgacat caagttgggc gaaccgctca gcaatgacgc attgctccaa
     8161 ctggactgta ccgtgctggt tcctgccgcc ctgtccgaac aaatcaccga agccaatgcg
     8221 gcgaagttac gttgccgcat tctggcagaa ggcgcaaacg gccccacgac actggaggcc
     8281 gatcgcatcc tcaccgataa gggggtcttc atcattcccg atattctggc caactcgggc
     8341 ggcgtgatcg tgtcgtattt tgaatgggtg caggacgtgc agcgcttctt ctggaaagca
     8401 aaggacattc aagaccggtt acaagacatc atcaccagcg ccttccatag aaccctgcac
     8461 ttttcgctcg aacggcgaac aacgatgcgg atggcggccc tcatgtcggg catcgacaaa
     8521 gtagcccagg cccatctcca acgcgggctc tacccgtaaa ccctgtctat gctgaacctg
     8581 cgattcacag tatgacccga tacatccttg cggcgattgc cggcatctgg atggccgacg
     8641 gactcgccct gctgagtgcc cctctgctcg tgatccggcg gctgcaggaa tccctcgaga
     8701 cggctccgaa cctgctccgc tggcaagcga ttggaatcgg tctcgggctc atgctcctgc
     8761 tctggtcgac cccgctgccc tatcaaccac tctggtggat gaccggtggt gccatggtca
     8821 tcaaaagctg ctttttgacc tggggcccca ccgcctggcg aacaccgctg ttgagttggt
     8881 gcttcacgcg cgaggcggtg gactatcgat tcttcggtct ctggctttgc acgcttgccg
     8941 tcctgctctt gcatgcgtta gggttgctgc acgggtaacg cgtcgccgca gcttcacctt
     9001 ggaccggtac catcctatga gccaccaatc cattgcctct ctctgggaag aacacagccg
     9061 cgacggctgg cctcaatttt ccagcccgaa tgaaggccag ttgatgacgc tggataccgt
     9121 gatcggcgga tgcgcggtgt tttatctcga cgggcaaccg gaaatggata gccatcgcct
     9181 tgcaatcctg gaggattgtg tggccgatct cgatggcctt cttgaagact tgtcggatga
     9241 gagcctgggc tatttccagc gccttcgccg gctggcgacc gctctcgtcg acgtgggacg
     9301 gcagccctaa ctctgtgccc gatctcgggc gaggaccggc cctcaggccg acccccgccg
     9361 tcgctcattt acggcacctc gacgatgtcc ttcttcatcg aaccgagtaa tgccagaagc
     9421 tcgccctttt ccccagcagg caccttgaac gtgtcgagcg ccgccaccag atcctgaacc
     9481 aacgccccga aatccgctga gctgatttgc atgcccaagt gcgtcgcctt catctcgcgc
     9541 ccctgatatc ggcaaggtcc gcctgttgcc tggcaaacct gatcaacgag atgccccttc
     9601 aacttaggga tgtcggtggt cgcaaaccgg ttgttgatcc gtccatccgc cgcgacattc
     9661 gccacaaact ggtcgaccac cgccgtaatc gccggcttgc cgcccaatcg gtcgtacaac
     9721 gactttgccg caggagcggc cgccgccgcg cgcgaagtct ggctgccccc cccggtgtcg
     9781 gcgcatccgc cacacaacgc cagggccccc aagagcattg cccccatccc gtatttcgat
     9841 accatcgccc acctccttga tgatgaatgg ccggttgcct gacctcgccg ccgacaggac
     9901 atgcgaagcg ctttgtgaag cgacattccg gttgacgatt caccttagga gatctatgat
     9961 ctattcgtct aatatattgt tttcatactt tccatagtct ttggctatag ctggtctgaa
    10021 ctctcatgga actgcggcaa cttgaatatt tcatggccgt cgcgacgcac cagaatttca
    10081 gccgcgccgc ggagcatgtg catgtctcgc agccttcgtt gtcgattcag atcggcgggc
    10141 tcgaaaagga gttgggcacg cgtctgttcg accgcctcgg gagaaaggtg gtcctgacgc
    10201 aggcaggtga actctttcag gtacatgcag agcgggcctt gcgggaggtg gagcaagcgg
    10261 aacaggtcgt gcacgaactg ctcggggcga aacgcggtcg cctgatcgtc ggcacgctat
    10321 cgacggtcaa ttcctatatg attgcgccgc tggtctcccg attcaaacta cgctttcccg
    10381 acattcatct gcaggtgcat gcccaaccgt cttccgagat cgtcaacgga ttgctggcga
    10441 atcggcttga tatcgggatt tgtctactcc ccctgactca tgcgcacgtc accaccattc
    10501 cgctgtttga ggaacgtctc gcgctcatcg cccccgccag tatgaacatc ggaaaacgcc
    10561 gtgcacgcat gcaggatctc gcacaattgc cgttggtctt gatgccggca gattattgtc
    10621 tgcggaaaat ggtcgaatcg gaatgtgcga aggcaggtgt gcacccgcag gtggttttgg
    10681 aaatgacttc cccggaaggc attcttcagg cggtagcgga aggaaccggg gcaacgatcc
    10741 ttcccgagct ctacgtcaaa tcccggctgc cggcgtcaca actccagatc atcgatctgt
    10801 acgatcccac gccccgtcat accgtcggac tcgcctacct caccaaacgg catcggggac
    10861 aagcggccga agaattcgca gccctgtgtg aaactacgat gcgtgatcta cagtcagact
    10921 ccacacaacc tccccgcaac aagcgcaaag gaagagccgc ctaagatctc aaaccgcctt
    10981 cctgcagagc ccgaatccgc gcgtctgcag ctcgcaataa gcctgcggcg accttgaaag
    11041 tcagacagcc gcttggatag aatgccctgt tgcctgaccc tctcctcatt tatgtgaccg
    11101 gtagtggcga cccggacaaa ttttcagcat gggcgttaag gaggcattca tgatgcagcg
    11161 tacacggaca ttcacagcct taatgactat gctggggtcc ctgtgcctcg ctgccgtcgt
    11221 gactgccgaa ccttatgaac tgagcaagaa cgacgtaact gacccgaaag gagtcgccag
    11281 ccaggatgtg tcactgttcg gaatcaagct gggggatgat gaagcgaagg ctctcgacgg
    11341 gctggtgaac gaaaaaatcc ccggcatcaa ggcggaacaa gaagccacct ttattttcct
    11401 gctcgatcag cgcaaaccga ccgggccaat ggccggcgtg cgggtgcaag acggcaaagt
    11461 tgatctcatc ttcatcaaca atcgttttgc gtttaagaca cgcggcatct tccgcaacgt
    11521 cctcaacagc gaaagccccg acgatgtgcg caagatcctg ggcaaggaag attatggcga
    11581 cgagaatgtg atgggcgcga tgctcgccta tgacaagcag ggctttcagg tgaattatct
    11641 cggcaaggac gtcaacgtgg agttttcact cccgcactaa accgtcacag aggcgattcc
    11701 cgctcagccc ctcgcaggtt cctggccttt aactatccga tcagtccgcc atcacgccct
    11761 gcgcatcaca ggacgcactc gtgcgagcct cgctgaaggc gagatcagca cggattccgt
    11821 gcaaccattg gcaatggcga aatttatcgg gccagggcgg cgcggctatc gctcagacgc
    11881 aagccgtaat tgatgaggct ggtcgccgta ttccagcgac gcttggagtt gaggatcacc
    11941 agcagcagat cactgccatc ctgggagact ttcgcgatca ggcaccgacc ggccttcgag
    12001 gtaaaccccg tctttacccc ttgcaccccg ggaatccggc caaggagccg attggtggtg
    12061 cgtaagacat aggcgcgatg ctcgttgatc ggcatgatga tttcccgctc ttcgcggacc
    12121 agttccttga atacgggatg gtgcaacgca atctcgctga gcttggcgag atcttcggcg
    12181 gtcgaataat gttccggcgc atcaaagccg caggcattgc tgaaatgggt attgtgcagt
    12241 tcgagcgccg cggccttggc attcatgaga tcgacaaacc gggcttcatc gccgccgacg
    12301 tgttcgctgg ccgcgaggca ggcatcgttc gcggaaacaa tcagcatcgc ctttagtaaa
    12361 tcttccagtc ggaatatttg tcccgtgcgc agccgcaggt gcgttttatg ggcgcgggcg
    12421 gccttagggc tgacggtcac ttcatcatcc agatggccat attccaggat cactaacgca
    12481 gacatgatct tggtgaggct cgccggggac aaccgctttt cgctttcaaa ctggtagagc
    12541 gtcgtgcccg tcttcaattc cttcaggaga atgctatgcg ccggcacgtg ccgccaccga
    12601 aggctgtgat gcgcttgttt cgccgatggc accggcctgg gatcgtaggg aacggtaatg
    12661 acctcgtcat ccacatcgtt gtcgatcgcc agggcctgac cagtccaaag ggcgcccatg
    12721 aggaacggaa tgaccatgac ggccaccggc aacatccgat gtgaacggtt catgcggaat
    12781 atctttgctt tcttgtgacg agcagaggga ttctggcggt cacagggtat aggtttctcg
    12841 aaccttcgtg ccacgtacac tgctggcgat gactttgtga aaaaaccgga gcaggtcggc
    12901 cagatcgatc cagaacccgc aattcaggca gcgtgcatac agtcggcgat tcatgagcgt
    12961 gtaatgccgc tccaccatca tgaatccttt gcatttcagg cagtgcatcg cccgaccatt
    13021 gccccttcga catgattgcg tagacgtctc ggcgcatctc agaccgatac caacgtcgtc
    13081 atttgtttag cggagacgat tgaggataag ggcgaggcag ccggccaaca acccaccccc
    13141 gaagatcgtg gtactgaagg acaggatcgc gccggaactt cccatcgggt tggtccccga
    13201 caccagatcg cgtaccccgc cttggaccat caagactgcc agcgtcgtca ggcagcccat
    13261 gctaaaccac cacaaaaacg atcgcacgag cccccgcggt ctgatcgctg aaaatggcgc
    13321 aggacctgtg tccagcgact ttttcgaact ctatccgagc cctatcgagg tgtcaagcaa
    13381 actgcctgtc tcttcttcgg ttgtcgcggc tcaaatctga atcggccgct attccggttt
    13441 actgtttggc gggatctgcc ctttccggcc gtgatgcaga aacaccgaaa cactggccgc
    13501 cccgttatcg gccgtcacaa gccccggctc ctctccgttg tcggcagaga cctgaaaact
    13561 ggccacggca aacggcccgt ttttcgtgcg gtagttacgc ggcgggtaat ggaatgtccc
    13621 gtcgccacgg ccgaacaaaa tagacaggtc cgtggactgc aaattgacga tcgctacatc
    13681 gtcgatatgg tcgccatcga agtcatgggc cacgccgaaa ttggggctgg catccgcgcc
    13741 ggaatccttc cccggctgaa aggtcccatt cccgttgccg aggaaggtgg taaaactatc
    13801 cccctccccg ttgatgacca gcagatcagg taggtggtcg ttgttaaagt cagcgaaact
    13861 gacccccaac ggccgccgac cggttttgta gtctttggga tcgcggaacg tcccatcgcc
    13921 attgccaatc catacagaga cggcgctcaa catcggccca ccgttcgtga cgaccaaatc
    13981 cggctggcca tcttgattga gatctttcag cgccacggag gtgggagtat cgccatattc
    14041 gtattgcacg ccgggccgga attcgccacg ggcgctcccg agaaaaatct tcaccttgtc
    14101 gttgcgtaaa gccaccgcta aatccggatg cccatcgccg ttgacgtcct ggctggagat
    14161 ggacaccggg gcgcgatgga ccgggtactg gggaccttca tcaaactttc cgttgcctcg
    14221 cccgaacagg atggagatct gatcccctcc tgaacaagcc agcgcgacgt cgagttggtc
    14281 atcatggttg aagtcgttga gggcgaggga ccgtggctcc tggcatacct tgacctgaac
    14341 ctggtcccga aaggttccgt cgccgttgcc gaacagaagg gaaatcgaat tgctcgagat
    14401 gttggtcgtg atgaggtcgg tgatttgatc ccgattgaag tcggccgtcg tcacggtcgt
    14461 cgggtttttg ccgacggcat agctttcaaa gtaataaaat ggatcgggcg ggacgtacgg
    14521 atccgttttg gagcaggcga agaggagcgg caagccggct atgagtgcca accccactcg
    14581 accgatcgcc cgcctcttgt tggcataggt attgatggtc atcgccatcc cgatgaaaaa
    14641 agcatgacat tccggccaag tccatgcttc gccgctccca atcctgccgc gctgagcgga
    14701 gtatacagag cccccttctg cttcgcaacg aagtccccgc gtcagggttg cggtgtgggg
    14761 cttggtcgtt gtgctccccc cgaatggact cggacgtcta ggcctttcgc ccctttgaaa
    14821 acttggaaag ccttaggcta caatgcggcc caagtgtgga ggaggtgccc atgagcaaga
    14881 aagtcacaat tccgttgtcg atgtatggcg tcgcagaagt cctgaaatgg tgtattgatc
    14941 gcaataacgg ccgtgtgccg ggagtcgata cagaagggtt caagcggatg cagtccctgt
    15001 tggccgagaa gccgacgtcc aacgactatc tggcgctcga tcaattctgg aagaaacaag
    15061 tcgcactgga attgacggaa gacgaagttt cgaccgttga ccgttgcctc tacgacattc
    15121 cgaacttcga taacgaaccg ctgccccaga tccggcataa attctggccc caagcagccg
    15181 gcatcgcggc tcactaatcg acagtctcga tacttccctc aatgtccgat atcacccaca
    15241 ggcccttggc ttgtgggtga tatcactttt cacgtctgct ctcgcaccag cgtcgaccag
    15301 tttgatcatc cctgagaagg ctgtttcaat ttcagccgct tcagacgatc tgtcagatct
    15361 tgccatcgcc gagagctcaa aagaaatgca ggagatgtgc aacgccgtgc catgtgcgtg
    15421 ggggcacccc agacacaaga tggaagcaca acagtggaag tgagagcgac gtggagaaag
    15481 agatgagaac agcgccgcca ggcatcatca tggcgacgcc gtcgattctt acagagaccc
    15541 ttcgcccttg aggaattttc tgaatcgtcc catgaggtcg gcccccaaag tgccgccttc
    15601 cggctttttc acttcgggat cactgaagtg ggaacgaatt tcctgcagcc gcttttccgc
    15661 ttgatcgttg ccttgcaacc gcttggtctt ttgaagtgcg gtgtcaaagg catcaaacgt
    15721 cagctcgtta tatccgaagg accggattcg cttcacggct ttcatcatgg cctggttgcg
    15781 aaacgtcgtg agatgctctg agtcgacttc tttcaaaccc aacttgcggg ccctgcgttc
    15841 ggccgcttta cgaatgccgc tgcgcacaaa atcgggcgag gtctgcagac gcttccaggc
    15901 ttcgtcgctc caggccacgc gctcctgagg cgcttcccac aactgcacgg cggtctgctc
    15961 gtcgattctg gtcaacccct tctcccgcgc catctcctca gtatcatgcc ggatcatgtc
    16021 actcacgaag tccatggcga tcggcggaga ctctttgatc ttctgctgca ggagtgctaa
    16081 tgcgccttcg gtccattcca acggagtcgt ttcgcgctcg tggatctctc ccaaggcttc
    16141 gaccttttcg aacaggtcga cattgacctc catgtggccg cctttgcgag caatctcatc
    16201 ggcgatctgc ttgatcatcc ctcgcataaa ctcggggacc gcagcgaggc gctccttggc
    16261 ggcggcggtc cagggcagct ggcctttggc catttgatcg gccgcctctg ccatgccgcc
    16321 ttccccaccc atggtcccca tcatctgccc tttgaactgc tcgaggatct cttcggtgat
    16381 ttcggcatag cccaactcac gcgccttctt ctcggccagg cggcggacca ttccccgcaa
    16441 aaacatgggt gcgcgctcca tgcgtttaag cgcaccgtca ctccaccgca cctcaggggc
    16501 tgttatattg gacgactctg ccacggcatc actcctgtta cttattgagt aattccttca
    16561 attccttgcc tgccttgaag aatggcacac gtttagccgg caccgcaact gtcgcgccgg
    16621 tcttcgggtt gcgcccttct ttcatgcgcc gggcacgaag acggaagctg ccgaaccctc
    16681 gaatctccgt cttgttgccg ctacgcaggg aatcccgaat gcaatcgaaa atcgtattga
    16741 ccacaatttc cgcctgccgc ttcgtcaacg tggtgacctg ctccgatacc cgctcgataa
    16801 tctgcgcttt ggtcatcgtc cctctcctcg tgggtggggc ttacctacag gtgaattgct
    16861 gcgtcgccat gccgatcatg cttcgaggcg ctcagaacgc catcaggtat ttcagtttca
    16921 cgccggtatt caactccagc ttgggaaaca ccgacgacca ccgggattcg atgatctccc
    16981 ggaatgaaaa tcgtttgcgt ggctcgacga ccttcggctc gccttccatg ccggcgatgt
    17041 ccgccgcaat atggatggcg tcgtcgagat cgcccaattc gtcgatcagc cgcgcctctt
    17101 tcgcctgccg cccggtataa atccggccat cggccaatgg ctctacgtcg gacacttcca
    17161 gcgaccgtcc gtctgccacg gcctgaataa attgctgatg cacgtcgtcc atcacggact
    17221 gcagcagctt acgctcttca tcgctcattt tgcgtaaagg cgatccgaca tctttaaaac
    17281 gcccgctctt gatgacgacg ccttcgaccc cgactttttt catcaggcct tcgaagttcg
    17341 ccatttccat aatgacgccg atacttcccg tcaggctgcc gggattggca atgatccggt
    17401 cggtggctgc cgcaatgtaa tatccgcctg acgcggcaac cgttcccatg gaggcgatga
    17461 cggccttgtt gcttttgttt ttcacccgct ttacggcgtc gtgaatttcc tgagacggta
    17521 cgacaccccc gccggggctg tcgatccgca acacgatcgc cttcacgagc ggattctcgc
    17581 tgtattgctt taactcgctg atggtcgctt gcgcatccag gatcaccccc tcgatgcgaa
    17641 tcagggccac acgatcctgg gtggagaaat cgaggtcggg gaggagcgcg ttcaacagaa
    17701 tcaacgctcc tcccacaatc acgatggccc aaaggatacg gcgcagtagg ctccgctgtg
    17761 gtttccccgc cgtgtctgct tgtgggccca ttcagtctcc aggcgtttag gcttcggaat
    17821 cgctctggtt acgcttccgg ctttgtttgg ccgcgcgacc cagggtttga tcgattccgc
    17881 cctgcgaggc atggaactca tccacctggc gacggtcgga atccagctga tgatcgcgaa
    17941 ggctgagcgc gattttccgt tcatcgcggt caaccttgat gatcttcgcc gtgacatcat
    18001 cactcggctt gaacttttct tccatgcgca cgttggcgtc cagacccact tcgctgatgt
    18061 ggatcaagcc ttccacgtcc ccatccaatt cgataaagag gccgaaatca gcgatcttgc
    18121 tgaccttgcc ggtgatgcta tcgccgaccc gatatttgtt gggaatctgc tcttcccacg
    18181 gatcgcggga caattgcttg taccccagcg agagacgttc cttttcctta tcgatgcgaa
    18241 tcacgacggc atccaccttc tggcccttct tgaagagctc cgacggatgc ttgatgtgct
    18301 tcgtccagga catgtcggaa atgtggatca gcccgtcgat gccttcttcc aagccaacga
    18361 aggcgccgaa atcggtcagg ctcttcacct tgccttcgat ccgcgtgccg gctggatatt
    18421 tggcttcgat catgtcccag ggattcgggg ccgtctgctt catgcccaag gaaatcttgc
    18481 ggcttcccgg atcgatattc aagacggccg cttcgacctg atcacccacc gacaccacac
    18541 gcgagggatg tcgcacttcg tgcgtccagg acatctcgga cacgtggacc aatccttcca
    18601 cgccgggctc cagttcgacg aacgcgccgt aatcggtcag gctcacgacc cgcccgcgca
    18661 cgcgcgttcc caccgggtac ttcgcggcca cgccggtcca gggatccgcc gacttctgct
    18721 tgaggccgag cgaaatacgg ccggtttccc gatcgtactt gagcacggtg acttcgactt
    18781 tgtcgctgac ctggaacaat tcggaaggat gtccgacacg accccaggac atatcggtga
    18841 tgtgcaacaa cccgtcgatt ccacccagat cgatgaaggc accgtaatcg gtgatgttct
    18901 tgaccgtgcc ttgaatcaac tggccttcct tcagcgtgga cagggtcgtc tgacggcgtc
    18961 gatcgcgggt ttcctccagc aagacccgtc gggaaaccac cacattgcca cggcgatggt
    19021 tgatcttgat gatcttcagg gggaaggtct tgccgaccaa cccatccagg tcgcggacgg
    19081 gatgcagatc gatctgtgaa ccgggcaaga acgccttgac gccgatatcg accatcatgc
    19141 cgcccttgat gcgcgaaata atcttacctt cgatgctttt ttcttccttg tgcagcttct
    19201 ccaattcctc ccagattttc atcttgtcgg ctttttcttt ggagagcacc aggttgccat
    19261 cagcgtcttc acattcttcg aggtacacct gaaggcgatc gcccactttc aattgcccca
    19321 attcttcctg tgagaactgg tcggcgggaa tcatcccctc agacttgtag ccgatatcga
    19381 cgaccacttt gtctttgccg atcgcgacca ccatgccctc cgtgatggta ccttcctcaa
    19441 aattccggaa ggtctcctca tacatcgccg ctaaggcatc gtggtcgagc ttgggttcgc
    19501 tttgtggtgt ggcagtactc ataaacggtc cgtcctccgg cctatgccgg gtgctgatag
    19561 tgaaaaaatc cgagtcttac tcagcgttgc aagacttggc tgtcggtgtg gcttctcgat
    19621 cgtgagtgag cccggcgtgg gcctgcccct ctccggggtt cggcacctgt cccagctctg
    19681 caatcttggc catcaccgta cgactgacat gttgataaaa cactttgcct tccaactgcg
    19741 cggcgtctgc cgagaaatcc aacggttcgc cataggtcac cgtcacgcgg cgaaatctcg
    19801 gccacttggc cccgggaggc agcacttcga acgtccc
//
LOCUS       DAOQPD010000073        19825 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1357_length_19825_cov_15.323217, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000073 DAOQPD010000000
VERSION     DAOQPD010000073.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 19825)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 19825)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19825
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1357_length_19825_cov_15.323217"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..8965)
                     /locus_tag="PK063_14700"
     CDS             complement(<1..8965)
                     /locus_tag="PK063_14700"
                     /inference="COORDINATES: protein motif:HMM:NF036757.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase-like domain-containing protein"
                     /protein_id="HMZ98349.1"
                     /translation="MNTIIFPATWKLRNRTDLPAAGKLVGELQSALLKLKLEVKPSDL
                     ARKEMGTSTVEAVKAFQTRVGLPVSGKLSQETITKLNAELAHNFVAHNKTRTGRLQDM
                     LQQLGQQLDMGEMKARKFGPSTEHALKTVQATLGVPQDGRISEDVSNKIREEALKKRL
                     NTKTQKAQVQRILLRALHVAKLKDVRINAAELTGKQIGPSTQAAIKSVQTKYGLPATG
                     QLDAATVDRLTSIAASIPEPVRQLKARNAAELKLLKKSARLNMKNEHVGDVQSALAFL
                     DFTVNESEFKNKIFGKSTRDALVSYQQARGLAVTGHAAGETLKSLNREIKRANPAVAA
                     GEFPYHMRGSVRDEHWQGMSDVTVQVWEKLVRGQGTKLAERKTGTNGFFDIPYDPPRE
                     TANKQVKQPYYVQIKAVDRANQEIGSKLLFNPTRIAWVNFTKGNHPYRGASEFQVRMT
                     AVTKAIGNSKVVDLVQPAADRQISRAAQAAGLVDEDVMRLVLAHRIAARLSQVPLGAE
                     ACYAFIAQNLPSTLPGDLIESTEDWALIDNLVDLAANGLAFMEDDLKALAFDNAITLN
                     LMPIAVGLQKDAILAALAQLKQTYALEKPILVGNGSLKGLLELSAISQAHYSSVASAF
                     LKHKSFGSEFWSDVSARPAEFGGSDAIKDLRTTVEVGHVTKNFVPMLAALKQKIADPN
                     VQAINSARDLAKLTHDEWVGLINANGKQVPPNLAGSPAEKVNTYAETLVTQSERMFPA
                     VALVARASRSTTNPLPNVKSVQALMDANPDLDLGTQNLDIFITRQNLNIDDVTMTSAR
                     VLQRVHRIAPTAAVGQVLLDYKIHNSAQIVGMGKDKFVASLTKDMKVSPRMAMTAYGF
                     AEYQYAQVLQRIGDYRFDFHRADPKAIVDHTYTKAELPAELAAIPNLETLFGSLDFCA
                     CDHCQSVYGPAAYLADVLRFLDTHPSKVANKTVKDILFGRRPDIGHIKLNCQNTETPL
                     PYIDLVCEVLENAIAAPQPMPDFSFQTTRPPVELKAAPEHVRFEAYEKLRIADFPLNT
                     AFDLWQEQTRVFLQHLGVPRWELMEAFQVPEVPGIPAAPPAPAVPPRPAVPSNISIAG
                     EYWGMSTHETAIIVAENENTDAKQKVYWGITTPAVPQEMSVADFLRRSALSYNELLDL
                     LYVLNPSGDPHNVMLDRPNATCDTELQKVVNLNAERLDKIHRFLRLRRHVSWSTWEID
                     LLIRTAAIGNGKLNESCLVRMKQFAQLQKRLGLSVDRTLVLFGDINAESRVRPDRPTQ
                     SIPSLYQDLFQNPAVANPVDAAFGLPIAAGTHIVDTDPKHDHRRTILAAFALTTVDFE
                     RLLSKLPNNDLSVANLSMIGRYAWLTKGLALSVKDLLALEARSGVTDIFATPKITLDF
                     IDSVDWVTKSAFTIDELDYLLTVNPDSSLGLREAALTQYIEALRQALRSDQAANKAGV
                     IANQVAASFGIAADQAQLLVEQITLSGITLSQVLQDPKLVAQDNAGKFAKDVTLANFP
                     GLYTAYRLLHKATFILLRFKLDVLTLKWLLANAGTFGLLSPNALPVENAPGALLFSAW
                     IKLAKWMYFKSLFPEPEQGSLPGLFDLALVPTTPVPDVKAAIAKLTQWETSEVEELVT
                     GLSLQHDGVPSSFVDIENYLRMDKCWRIAKRIGVTPAKASAWANRDNNAVQSLTAQEA
                     KQAAKSKYDDAVWLQTVTPLEDTLREKKRDALIGYLVAHSLATVSAEIEQDGKRYANP
                     AYWRNGDDLLKYFLIDVEMCACQLTSRIKQAISSIQMFVQRCLLGLEQLHVEVSRSEQ
                     QDAVSENSWKQWKWMKSYRIWEANRKVFLYPENWIEPELRDDKSPFFEELESELLQSD
                     MTDENAEQAFLHYIQKVHEVARLDIVGAYYELDDVELPRDGDDLSPDVNIMHVVGRTR
                     AQPAIYYYRKFDLNFEEWSAWEKIDLDIQSDQVIPVIYNRKLYLFWLSFMEKPQKVKK
                     VPPAKPTAPEKDAQDAPEPPNQLELQLCWSARKDKGWTSKRVSHQKLIHPWQRPLFSY
                     NLKPRYKSRENLLWLDVYISQSQAFNSTEFWDAYRNVSDYVTARNPFDETARPWHSSS
                     FVFDGDVVDVKMKALAGQYRIMNANGVANESLSKTTSLAHVRDNFGEAGRSINQLSGR
                     YEIAPRLPLPDGMHYHNTKLTNNKRTLNGSRANVLENSHTRTLLSGARSPFEIVASQH
                     SIVFDTAAWGPVPFFYQDNTRAFFIKPEWQQVIMGYNQTLQTYNYNFFPFYHPYTALF
                     MRELKRSGLDGLLNRQIQTAPQGYYPGNSFDFSSYNPGSMSLPDKTAKYDRVDFERYG
                     AYALYNWEIFFHAPLMIACKLSQNQRFEEAMRWFHYIFDPTNTESPDVPQRYWITRPF
                     FEQNSAAYRQQRIDNLLKNIEEHEGELRAWKNNPFKPHLIARYRPVAYQKTVVMKYID
                     NLIAWGDQLFRRDTIEAINEATTLYVLAHELLGRRPVKVPNVEHIDKSYNELAANGGL
                     DPFGNKQVDILMENFTGTPVQVTRTQSGTEPLPTLNVFYFGIPNNDRLLTYWDTVEDR
                     LFKIRHCMNIQGVVRQLPLFEPPIDPALLVKAAAAGVDLSGVIADLALAPAPYRFRQM
                     SQKALEFCAEVRSLGDKLLNILEKGDAEGLALLRSSQEIALQQAVRDIKKQQISEANE
                     NWASLEKSKELAQQKRSFYESREFMNPWEITAMSLSGASAVIQGSLAVGYVLAGALAF
                     IPKITGGVSGFGATPVVTVDPVDGKNFAEGAGHAMNALNAIMSILDRTGAMASTVGGY
                     WRRKDEWDFQGQLATTEIAQIEKQIAAAQIRLAIAEKDLENQELQIENSQAVDEYMRA
                     KYTNQQLYDWQARQIAAIYFQSYQLAYDMAKRAEKCFQYERGDSAATFVQFGHWSSLK
                     KGLLAGERLSNDIRRMEAAYLEQNSRDLEITKHISLTQYFPLSLVALKEAGACTVVLP
                     EWLFDMDYPGHYVRRLKSVSLSIPCVVGPYTSINCTLTLTKAAV"
     gene            complement(9201..9527)
                     /locus_tag="PK063_14705"
     CDS             complement(9201..9527)
                     /locus_tag="PK063_14705"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98350.1"
                     /translation="MALTMIDTYEVMYSANSFVTRIWLKGGNKNLGQLIFKPNGSALP
                     QDNMANGQVNLYYHLDDFQNALDLLRNEIPMYLLYSGSGGVSRTASRPRQKPSAREKH
                     RLTDSD"
     gene            complement(9710..18286)
                     /locus_tag="PK063_14710"
     CDS             complement(9710..18286)
                     /locus_tag="PK063_14710"
                     /inference="COORDINATES: protein motif:HMM:NF015497.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpvB/TcaC N-terminal domain-containing protein"
                     /protein_id="HMZ98351.1"
                     /translation="MAELKRESSDGNSAEKSFQVSAPAITLPKGGGAIRGIGEKFAAN
                     PVTGTGSMTVPIATSPGRSGFGPQLSLSYDSGAGNSPFGFGWSLSLPSITRRTEKGLP
                     QYLDAKESDVFILSGAEDLVPVLVQDANKHWAREELPDRTIDAKTYRIRRYRPRIEGL
                     FASIERWTNINDATDVFWRSISKDNITTWYGRSPDSRIADPSDTNRIFSWLICQSHDD
                     KGNVIVYGYKTEDSTNVFQDSSQKSLGKAHERYRSDQTRSAQRYLKHIRYGNGSPYFP
                     VLKSDAVWPEPPDAHVPDGSNVWHFEVVFDYGEHDAKAPTPNDAGSWPARPDPFSSYR
                     AGFEVRTYRICQRVLMFHHFPDEAGVGRDCLVRSTDFMYSNEVDHTDGRNPVYTFLTA
                     VTHTGYRRTNGSYDKGSLPPVEFEYTKPIVQETVEVMDSENLKNLPIGVDGTAYQWTD
                     LHGEGIPGILTEQAGTWFYKRNLSPISKRPGEFSPMECVALKPNLALAGGAQFMDLAG
                     DGLPDVVVLDGPMSGLYEHDKGEGWQPFRFFTARLSRDMRDPNLKFVDLDGDGHADIL
                     ISEDEAFVWHSSLAEDGFGPALRIAQALDEEKGPRIVFGDGTQSIYLADLSGDGLTDI
                     VRIRNGEVCYWPNLGYGRFGAKVMMDNAPWFDNPDQFDHKRIRLADIDGSGTTDIIYL
                     HRDGVRLFFNQSGNSWSQPYHLKVFPRIDDPVNILPTDLLGNGTACLVWSSPLPGDAG
                     RPMRYVNLMGKQKPHLLIKTVNNLGAEIRVHFAPSTKFYLQDKRDGQPWITRLPFPVH
                     VVERVETYDHISRNRFVSRYAYHHGYFDGEEREFRGFGMVEQWDTEQIGALIASGVFP
                     QSDNIAATSHVPPVHTKTWFHTGGYEGTDEVSQHFAREYYGAPEKNAQNYKALFDAYF
                     QTLLPDTVIPSGLTLEEEREACRALKGSMLRQEVYANDADHPGATLEQIQRARIPYTV
                     TEQNFTIQPLQPRGVNPHAVFFTHAREAISYHYERNTADPRIQHALTLEVDDFGNVLK
                     QAAIGYGRRVSPLAEQWDRDRQTTPLLTYTESRVTNAIKTPDAHRTPLPCEAITYELT
                     GYTPTRIAGRYRASDFVEPDPALPARLQLKFTDEVAYEAPATGNPCRRPIEWLRTLYR
                     SDNLSVLLPLEGLQPLALPGESYKLAFTPGLIAQVYQRNSAVLIPDPLQVFPVDRAPS
                     LSGDRGGYVDLDSNGHWWIPSGRSFYHSNEVSAPVELTEAQAHFFQPRRYRDPFGQNS
                     LIDFDGYDLLVKESRDALGNRFTVDTNDYRVLQPRLVSDPNRNQTEVAFDVLGMVVGT
                     AVMGKPLPAPVEGDSLTGFVADLTQTQLDGFFAVADPHATASALLQDATTRIVYDLDR
                     FRRTQRAYPNDPQLWQPSCGATLTRETHVSDLAPNQESKLQVTFSYSDGFGREIQKKI
                     QAEPDQGRFAVDVLEDRPIAYYRLNDSAESTRILDQSGNGHHGECSPTGITLQQAGLG
                     VDDAAILSDGQGSGRVVVPDSEQLNPKWITIEALINWFGPTGSQQRILEKSYSAGSPT
                     WPTYGLSILENGTVRLELVITGHSDPVLVTSKVKVSAHVPTHVAATFDGQTIQIYVNG
                     VLDTSWSVVGSIVSTFGSSKLGIGNQVERNRQFNGLLDEVVLYDQALAPGRIQSHVAK
                     VKTGNLPRRRWVGSGWTIFNNKGKPVRQYEPFFSTTHRFEFGTKVGVSPVLFYDPAGR
                     VMATLHPNNTYEKVVFDSWQQTAYDVNDTCAPRNQQTGDPRTDPDIVGYVAEYFKTQP
                     ATWQTWHAHRIGGDLGQHERNAALGAAAHADTPTTAHFDALGRHFLTVARNRIICPGH
                     DLDGTEENFATRVELDTEGNQCAVRDAMVQDGDPFGRIVMRYTYDMLGNRIHQLSMEA
                     GARWMLNDVASKPIRAWDSRGHNFTMSYDALRRPISQYVLGNTAESDPRTLNPPNAIG
                     LLVDRIEYGEPPANATEAQKREAQRLNQCTRIYRHFDPAGIAVSARLNVDGHPTEAYD
                     FKGNLLRTTRQLVSLYEKIPDWSQNLQLDSERFESSSRYDALNRPVQSIASISSERRG
                     NFKVIQQVFNEANLLERVDVWMERATEPSALLDPSVDAPTPVGVANIDYDAKGQRMLI
                     AYKTRDAKVIQTTYSYDRETFRLMHLYTRRGVDPKTARGVSFSEDCDNPQPPPPTIAA
                     PDKPPQGKACGLQNLHYTYDPAGNITHIQDDAQQTIYFKNQRVEPSNDYVYDAMYRLI
                     EASGREHLGQTAGITNPPTHHSHNDVPRIRRPHPNELDAMGAYLERYVYDAVGNLESM
                     QHQGLDPANPGWTRTYTYKERSQIESRKRSNRLTSTTIGNSNPVIEEYQHDAHGNMLG
                     MLQLQVMQWDYKDQLQMTQRQKVNEEDAEGEEPHGERTWYVYDAAGKRSRKVTELANN
                     GGLKEERIYLGGFEIYRRHSGPDSGLVRESLHIMDDKQRIALVETRNDVDDGTLKQVT
                     RYQFGNHLGSASLEVNEQAQVISYEEYAPYGSTSYQAVRGQTETAKRYRYTSKERDEE
                     SGLYCFGARPYACWLGRFMRSDPIGIRGGLNQFAYAAANPLRNVDPTGKAPQPAQKPQ
                     TGNHRDNTLDYDRLEREMHLKAAALEGAMTTQSIVTEHETLVKTTGKGKYFGSKSHFA
                     KDPKSDRSNLEECNCILYQMKPVDAYIQNLEAVGEVPKGTWDLIRSVTEDSDRRDTVL
                     MEQLRVNAGFRTLLVDRGEMVGKYTLSRAVERASGLYPPKSDPVTGLDSGAPLDVRTH
                     IDVTFKNTKKDRTKALEYLSSLPFAIVTEDYGNHTLVLSFGVVYEAHWAAEPTEQDQG
                     KPDPMFERTSLDIYMKTHKNLVFAVPPDSK"
BASE COUNT         4132 a         5318 c         5583 g         4792 t
ORIGIN      
        1 gcacggccgc cttggtaagt gtgagcgtac aattgatgct cgtgtatggc cctacaacac
       61 aaggaatgct gagagaaaca gactttagcc gccggacgta atgtcctgga taatccatgt
      121 cgaacagcca ttccggcagc acaacggtgc aagcaccggc ttccttcagc gccaccagac
      181 tcaacgggaa atactgagtg agcgaaatgt gcttggtgat ttcaagatcc cggctattct
      241 gctcaaggta ggccgcttcc attctgcgta tatcgttgga gaggcgctct cccgcaagaa
      301 gtcctttctt caagctcgac caatggccaa actgaacaaa cgtcgcggct gagtcgccac
      361 gctcatactg gaagcatttt tcagcgcgct tggccatgtc gtaggctaat tgataacttt
      421 gaaaatagat ggccgcaatc tgtctcgcct gccaatcata caattgctgg ttcgtatact
      481 tggcccgcat gtattcgtcg acggcctggg agttctcgat ttgtagctct tggttctcga
      541 gatccttttc ggcaatggct agacgaattt gcgctgcagc gatctgtttt tcgatttgtg
      601 cgatttcggt cgtggccagt tgcccctgaa aatcccattc atctttacgt cgccagtatc
      661 cgccaactgt cgaggccata gctccggtcc ggtccagtat ggacatgatg gcatttaacg
      721 cattcatcgc atgtccggca ccttcggcga aattctttcc gtcaacggga tccaccgtta
      781 ccacaggagt ggcaccaaaa ccagaaacgc ctcctgtaat cttcggaatg aacgccaatg
      841 cacccgctag cacatagccc accgcaagtg aaccttgaat aaccgctgat gcaccgctca
      901 agctcattgc cgtgatttcc cacggattca taaactcgcg actctcatag aagcttctct
      961 tctgttgcgc tagttccttg ctcttttcca aactagccca gttttcattc gcctcactga
     1021 tctgctgctt cttgatgtca cgcacggctt gctgcaatgc aatctcctgc gaagagcgca
     1081 gtagtgccag accttccgca tccccttttt cgagaatgtt caagagctta tctccaagac
     1141 tcctgacctc agcgcaaaat tctagcgctt tctgtgacat ttgacggaaa cgatacggcg
     1201 ctggagcaag agctagatct gcaatgacgc cgctgagatc aactccggct gctgcagcct
     1261 tgaccaacaa ggcaggatcg attggtggct cgaagagtgg aagctgacgc actactcctt
     1321 gaatgttcat gcagtgccga atcttgaaga gacgatcctc gaccgtgtcc cagtacgtca
     1381 gcagccggtc gttgttcgga atgccgaaat agaaaacgtt gagggtgggc aagggttcgg
     1441 tgccggattg tgtgcgggtc acctgtacag gtgtacccgt gaagttctcc atcaagatat
     1501 caacttgttt gtttccaaac gggtcgagtc caccatttgc cgcaagctcg ttgtaagact
     1561 tgtcgatatg ttcaacattg ggaaccttga cggggcgtct gcccaatagc tcatgggcca
     1621 gtacatagag ggtggtggcc tcattaatcg cttcgatagt gtcgcgccga aataactggt
     1681 cgccccaggc gattaagtta tcgatgtact tcatcaccac ggttttttga tacgcaaccg
     1741 gacggtaccg tgcaatgaga tgaggcttga atggattgtt cttccaagcc ctcaattccc
     1801 cttcgtgttc ctcaatgttc ttcagcaaat tgtcgatacg ttgctgccga taggcagcgc
     1861 tgttctgttc aaagaaaggc cgggtaatcc aatagcgctg cggcacatcg ggcgactctg
     1921 tgttggtggg gtcgaagatg tagtggaacc aacgcatcgc ctcttcgaac cgctggttct
     1981 ggctcagttt gcaggcgatc attagaggtg catggaaaaa tatctcccaa ttataaaggg
     2041 cgtaggctcc gtatcgctca aagtcgacgc gatcatactt cgcggtcttg tcgggcaggc
     2101 tcattgagcc ggggttgtaa ctactgaagt caaacgagtt tccggggtag tagccttgcg
     2161 gagcggtttg gatttgacga ttcaacaatc catcgagacc ggaacgcttc aactcgcgca
     2221 tgaacaacgc ggtgtatgga tggtagaaag ggaaaaagtt atagttgtag gtctgtagcg
     2281 tctggttata gcccatgatg acctgctgcc actcgggctt tataaaaaac gctcgcgtgt
     2341 tgtcttgata gaagaacggt accggccccc atgcggccgt atcgaaaacg atgctgtgct
     2401 gcgaggccac gatttcgaac ggtgacctgg cgccgctcaa aagcgtgcga gtgtggctat
     2461 tttccagcac atttgcacgg ctgccattca gcgtgcgttt gttgttggtc agcttcgtat
     2521 tgtgatagtg catcccgtcc ggcagcggca aacgcggcgc gatttcataa cgtcccgaga
     2581 gctgattaat ggacctgcct gcctcgccaa agttgtcacg cacatgggcc agggaagttg
     2641 tcttgctcaa agactcgttg gccactccgt tggcattcat gatgcggtac tgccccgcca
     2701 gagctttcat tttgacgtcc actacatcac cgtcgaagac aaacgacgac gaatgccacg
     2761 gtctcgcggt ttcgtcgaag gggttgcgtg cagtcacata gtccgagacg ttccgatagg
     2821 cgtcccagaa ctccgtacta ttgaacgctt gggactggga gatatacaca tccaaccaga
     2881 gtaagttttc gcggctcttg tagcgtggtt tcaggttgta ggaaaagagc ggacgttgcc
     2941 aggggtggat cagcttttga tgtgagacgc gcttcgaggt ccagccctta tctttccgcg
     3001 cactccaaca gagctggagc tcaagctggt tgggcggctc gggcgcatct tgtgcgtcct
     3061 tttctggggc ggttggcttc gctggtggca ctttcttcac cttctggggt ttctccataa
     3121 aactcagcca gaagagatac agctttcggt tatagataac cggtataacc tggtcactct
     3181 gtatatccag gtcgatcttt tcccatgcac tccattcttc aaagtttaga tcgaacttcc
     3241 gatagtagta gatcgcaggt tgagccctcg tgcgaccaac aacatgcatg atgttcacat
     3301 caggagagag gtcgtcgcca tctcgcggaa gttccacatc gtccagctcg tagtacgctc
     3361 cgacgatatc gaggcgtgct acctcgtgta ccttttggat ataatggaga aacgcttgct
     3421 cggcattctc gtccgtcata tcggattgga ggagttcact ctccaattct tcgaagaatg
     3481 gggacttatc gtcccgcagt tccggctcga tccagttctc cggatacagg aagacctttc
     3541 ggttggcttc ccatatcctg taactcttca tccacttcca ttgtttccag ctattctctg
     3601 aaacggcatc ctgctgctcc gagcgcgaca cttcgacgtg cagctgttcc agcccgagca
     3661 ggcaacgttg cacaaacatt tggatagagc tgatggcttg cttgatgcgc gacgtgagtt
     3721 gacaggcgca catttccacg tcgatcaaga agtacttcag aaggtcatcg ccgtttcgcc
     3781 agtaggcagg attggcgtag cgttttccgt cttgctcgat ctcggcactc acggtggcta
     3841 gagagtgggc aacgagatag ccgatcaaag catcgcgctt cttctcccgt agagtatctt
     3901 ctaatggtgt gaccgtctgc agccacaccg cgtcgtcata ctttgacttg gccgcctgct
     3961 tcgcttcctg ggccgtgagg ctttgtacgg cattgttgtc gcgattcgcc caagcactgg
     4021 ctttggcggg agtgacacca atacgtttgg caatgcgcca gcatttgtcc atacgcaggt
     4081 agttctcgat atcgacaaag ctggatggga cgccgtcatg ctgcagcgaa agtcctgtga
     4141 ccagctcttc gacctcggac gtttcccact gggtcagctt ggcaatggct gctttaacat
     4201 cggggactgg ggtcgtcggt acgagggcca gatcaaacaa cccaggcaac gaaccttgtt
     4261 caggttccgg gaagagactc ttaaagtaca tccatttcgc aagcttgatc caggccgaga
     4321 atagcagcgc tcctggcgca ttctcgaccg gcagcgcgtt aggcgacagc aagccgaacg
     4381 ttcctgcatt cgccaagagc cacttcaagg tcaatacatc cagcttgaac cgaagcagga
     4441 tgaatgtagc tttgtgcagg agccgatagg cggtgtagag gcccgggaaa ttggcgagcg
     4501 tgacatcctt ggcaaacttc cccgcgttgt cttgagcgac caacttcgga tcttgcagca
     4561 cctgcgagag tgttattcca ctcagcgtga tttgttccac cagcaactgc gcctgatcgg
     4621 cggcaatacc aaatgaggct gcgacctgat tggcaataac gcccgcttta ttggctgcct
     4681 ggtctgagcg cagggcttgg cgcaacgctt cgatgtattg ggtaagcgcc gcttcacgta
     4741 ggccgaggga ggagtcagga ttgaccgtca gtaggtaatc cagttcatct atggtgaacg
     4801 ccgactttgt cacccaatcg acgctgtcga tgaagtccag ggttatctta ggtgtcgcga
     4861 agatatccgt cacaccggag cgcgcttcga gcgccagcaa atccttgacg gacagcgcca
     4921 gccctttcgt tagccaggcg tagcggccaa tcatggacag gttggcaacg ctcagatcat
     4981 tgttgggtag tttagatagc agccgttcga aatcgactgt ggttaaggcg aacgcggcga
     5041 gaattgttct ccgatgatcg tgttttgggt cggtgtctac aatgtgcgtt ccggcggcaa
     5101 tcggcaaacc aaaggccgca tcaaccggat tggccacagc cggattctgg aagaggtctt
     5161 ggtacaacga aggtatcgac tgtgttgggc gatcgggcct cacgcgagat tccgcattga
     5221 tgtccccgaa gagcacaagc gttcggtcca ccgaaagccc taggcgcttc tgtaattggg
     5281 caaactgctt cattcgcacc aagcagctct cgttcaattt gccgttgccg atggcggcgg
     5341 tgcgaatcag cagatcgatc tcccaggtcg accagctgac gtgccgccgt agacgcaaga
     5401 atcgatggat cttgtcaagg cgctcggcat tcaggttgac gaccttctgc agttccgtat
     5461 cgcaagtggc gttcggtcga tcaagcatca cattatgtgg atcacccgac gggtttaaga
     5521 catacagaag gtcgagcaac tcgttgtagc tgagggcgct ccggcgcaag aaatcggcga
     5581 cgctcatttc ttgggggaca gctggggttg taatacccca gtaaactttt tgctttgcgt
     5641 ccgtgttctc attctctgcc acgatgattg cagtctcgtg agtcgacatc ccccaatact
     5701 cacctgcaat actgatgttc gaggggacgg cgggtcttgg gggcaccgct ggagccggag
     5761 gcgctgcggg aatgccaggc acttctggca cctggaaggc ctccatcaac tcccatcgag
     5821 gtacgcccag gtgctgaaga aagacccgcg tctgttcttg ccataagtcg aatgccgtat
     5881 tgagcggaaa atctgcaata cgcagcttct cgtatgcttc gaaacgcaca tgctctgggg
     5941 cggccttcag ctcgacgggt ggtcttgttg tctgaaagct aaagtcgggc atgggttggg
     6001 gagcggcgat ggcattttca aggacctcac ataccaggtc gatatacgga agcggcgtct
     6061 cggtgttctg gcaattcagc ttgatatggc ctatatcggg acggcgcccg aaaaggatgt
     6121 cttttacggt cttgttggcc actttcgaag gatgcgtgtc gaggaagcgc agcacgtcag
     6181 caaggtacgc cgccggtccg tagaccgact ggcaatgatc gcaagcacaa aaatctaatg
     6241 agccgaacag cgtttccagg ttcgggatgg cagccaattc tgccggcaat tccgctttgg
     6301 tataggtgtg atcgacgatc gccttcgggt cggcgcggtg aaagtcgaag cggtagtcgc
     6361 caattcgctg cagcacctgg gcgtactgat attcggcgaa cccatacgcg gtcattgcca
     6421 tgcgtggact gaccttcatg tctttggtca gtgaggcaac gaatttgtct ttgcccatcc
     6481 caacgatctg ggccgagtta tgaatcttgt agtcgagaag aacttgtccg acagcagctg
     6541 tgggtgcgat gcgatgcaca cgctgcaaca cccgcgccga ggtcatggtc acatcatcaa
     6601 tattgaggtt ctgacgtgtg atgaagatgt caagattttg ggttcccaga tcaagatcag
     6661 gattcgcgtc catcaatgcc tggacgcttt tcacgttggg caacggattg gtggtgcttc
     6721 gcgatgccct cgccaccagc gccacagcag ggaacattcg ctcactttga gtgaccaacg
     6781 tctcggcata ggtattcacc ttctccgctg gggaaccagc cagattcggc ggtacttgtt
     6841 tgccgttagc gttgatcagt cccacccact catcgtgagt cagctttgct aagtctcttg
     6901 ccgagttgat ggcctgcacg ttggggtctg caatcttctg cttcagggcg gcaagcatgg
     6961 ggacgaagtt cttggtcaca tggcccactt cgaccgtggt cctcaagtcc ttgatcgcat
     7021 ctgaaccacc aaactccgca ggtcgcgcgc tcacatctga ccaaaactcc gatccgaagc
     7081 tcttgtgctt caagaacgca ctggcaacgg aggagtagtg cgcctggcta atcgcggaca
     7141 attcaagcag ccccttaagg ctaccgttgc ccacgaggat cggcttttca agggcatacg
     7201 tctgcttaag ttgcgcgagt gcggccagaa tggcgtcctt ctgcaaccca accgcaatcg
     7261 gcatcaggtt cagggtgatc gcgttgtcga acgccagagc cttgagatcg tcctccatga
     7321 acgcgagacc gttggccgcg agatccacca ggttgtcgat aagagcccaa tcttcagtgc
     7381 tttcgatcag gtcacccggc agagtcgacg ggaggttttg agcgatgaat gcgtagcagg
     7441 cctctgcacc gagcggtact tggctgagcc tcgcggcgat gcgatgagcc agcaccaatc
     7501 gcatgacatc ctcatccacg agacctgccg cctgcgcagc tcggctgatt tgacgatccg
     7561 cagccggttg gactaagtcc acaaccttgg aattgccaat cgccttcgtg accgcggtca
     7621 tccgtacctg aaattccgat gcgccgcggt atggatgatt acctttggtg aagttcaccc
     7681 aggcaattcg tgtggggttg aagagcaatt tgctgccaat ctcttggttg gcgcgatcaa
     7741 ccgccttgat ctggacgtaa tagggctgtt tgacctgttt gtttgccgtt tctcttggcg
     7801 gatcataagg gatgtcgaaa aagccattgg tgccggtctt gcgttcggca agcttggttc
     7861 cttggccacg gaccagtttt tcccagactt gcaccgtcac atccgacata ccttgccaat
     7921 gttcatcccg caccgagcca cgcatgtgat atgggaattc gcccgctgcc acagcaggat
     7981 tcgcgcgctt aatctcgcga ttgagactct tcagcgtctc gcctgctgca tgccctgtga
     8041 ccgccagacc acgtgcctgc tgataactca ccagcgcatc gcgcgtagac ttgccgaaga
     8101 tcttgttctt aaactcggat tcattgactg tgaagtcgag aaaggccaat gcgctttgca
     8161 cgtcgcccac atgttcattt ttcatgttaa ggcgggcact cttcttcaag agcttgagtt
     8221 ccgcggcatt cctcgccttt aattgacgaa ctggttcagg aatgctggct gcaatcgatg
     8281 tcaagcgatc aacggtagcc gcatcgagtt gaccggtggc cggtaggccg tacttggtct
     8341 gtaccgattt gattgcggcc tgtgtacttg gcccgatctg cttacccgtt agttcagctg
     8401 cattgatgcg cacatccttc agcttggcga catgtagcgc tcgtaacagg atacgttgca
     8461 cctgcgcctt ctgtgtcttt gtgttcagcc gtttcttgag cgcctcctcg cgaattttat
     8521 tgctaacgtc ttcagagata cgcccatcct gcggcacacc gagcgtcgct tggacagttt
     8581 tgagcgcgtg ctcagtgctt ggcccgaact ttcgagcttt catttccccc atatccagct
     8641 gctggccgag ctgctgaagc atgtcttgca gtcgtcctgt acgagtcttg ttatgcgcga
     8701 cgaaattatg cgccagctcg gcattgagct tcgtgatcgt ctcttgggac agctttccac
     8761 tgacgggcaa cccgactcgt gtctgaaacg cctttacggc ttcgacggta gaggttccca
     8821 tctctttgcg tgccaggtcg cttggcttaa cctcaagttt gagtttcagc agggccgact
     8881 gaagctcacc gacaagcttc cctgcagcag ggaggtctgt gcgattacga agcttccaag
     8941 tcgcggggaa gatgatggtg ttcatcgtct ggaactcctt tgctctcggc gagacacgaa
     9001 atcagagtcg aacgtggtgt tgattggacc tatcccacga caatgactgt caggccattg
     9061 cctcgagaga agcaatggcg tgcggccgca ttcaggcgtc gaagttatca gagctcagac
     9121 atttagccgg gggttactaa aatacttcat cgttcaagcc tacctctcaa cttcagttgt
     9181 gcgcgaagat tggcgattcg ctagtcggag tctgtgagcc tatgcttctc tctcgccgat
     9241 ggcttctggc gtggtcttga tgccgttctc gaaaccccac ctgagccgga atacaacaga
     9301 tacatgggga tctcgtttct gagcagatca agggcatttt ggaagtcatc caagtggtaa
     9361 tagagattca cttggccatt ggccatattg tcctggggta gtgccgagcc attcggctta
     9421 aagatgagct gacctaaatt cttgttgcca cccttcagcc aaatgcgtgt cacgaacgag
     9481 ttcgccgaat acatgacttc gtatgtgtcg atcattgtga gcgccatgag agagcctccc
     9541 tttcattcgc gagtgagtgc tgcactcgaa ctgacatgtc gacctcatca cgaaggcctc
     9601 ggagcaaatc aaagacttcc taccccgttg tttctggata agaaatccaa aaagccaata
     9661 agattaaggg tgagaaagct attcataagt tatgacttcg ccgtgtcgtt tacttcgagt
     9721 caggcggaac tgcaaaaacg aggttcttat gggtcttcat atagatatct agcgatgtgc
     9781 gttcgaacat cggatccggc ttgccctggt cttgctcggt tggctcggca gcccaatgtg
     9841 cctcgtagac aacgccgaag gacaagacca gcgtgtggtt gccataatct tcagtgacga
     9901 tggcaaaagg caatgagctc aagtattcga gtgccttggt gcgatccttc ttggtgttct
     9961 tgaatgtgac gtcgatatgt gttcgcacgt caagtggggc acccgaatct agtccagtga
    10021 caggatcgga tttgggaggg taaagtccgc tcgccctttc gaccgcgcgg gacaatgtgt
    10081 acttgccgac catctcgcct cggtctacca gaagcgtcct gaagccagcg ttaacgcgca
    10141 gctgctccat tagaacagtg tcgcgacgat ctgagtcctc agtcacactc ctaattaaat
    10201 cccacgtgcc ttttgggacc tcgcctacag cctcaaggtt ttggatgtat gcgtcgaccg
    10261 gcttcatctg gtaaaggatg cagttacatt cctctaagtt tgacctgtcg ctcttgggat
    10321 ccttggcgaa atgagatttc gatccgaaat actttccctt gccagttgtt ttaaccagcg
    10381 tttcgtgctc agtaacaata gattgcgtcg tcattgctcc ttcgagcgcg gctgctttta
    10441 ggtgcatctc ccgttccagc ctgtcatagt cgagtgtgtt gtcgcgatga tttccggttt
    10501 gtggcttctg tgcgggttgc ggcgctttcc ccgttgggtc gacgttccgt agcggattcg
    10561 ctgcagcata ggcaaattgg ttcagcccgc ctcgaatgcc aatggggtcg ctccgcatga
    10621 atcggccgag ccagcatgcg taaggcctcg caccaaaaca atacagtccg ctctcctcat
    10681 cgcgctcctt gctcgtgtac cgataccgct tcgcagtctc cgtttggccg cgcactgcct
    10741 gataactcgt gctaccataa ggcgcatact cctcatagga aatgacctgt gcctgctcat
    10801 tcacctccag gcttgccgat cccaggtggt taccgaactg ataacgggtc acctgcttca
    10861 gggttccatc gtcgacatca ttccgcgtct cgacgagcgc aatacgctgt ttgtcgtcca
    10921 tgatgtgcag cgattcccga acgagcccgc tatctgggcc tgaatgccgg cgatagattt
    10981 caaagccgcc gagatatatg cgttcctctt tcagcccgcc gttgttggcc aattcggtta
    11041 ctttgcggga acgcttgccg gcggcgtcat agacgtacca ggtgcgttcg ccgtgcggct
    11101 cctcgccctc ggcgtcctcc tcattgacct tctgccgttg cgtcatctgc agctgatcct
    11161 tgtagtccca ctgcatcacc tgcagttgaa gcatgcccaa catattgcca tgagcgtcat
    11221 gttggtactc ttcaatgacg ggattgctat tgccgatggt ggtgcttgtc aggcgattgc
    11281 ttcgtttacg tgactcgatt tggcttctct ctttataggt gtaggtgcgc gtccatccgg
    11341 gattcgctgg atctaagcct tgatgttgca ttgactccaa attaccgacg gcgtcataca
    11401 catagcgctc caggtaggcg cccatggcgt cgagttcgtt gggatgcggc cgacggatgc
    11461 gcggcacgtc gttgtgggaa tggtgcgttg gtggattcgt aataccggcg gtttgtccta
    11521 agtgctcgcg gccgctggct tcaattaggc gatacatggc gtcgtaaaca tagtcgttac
    11581 tcggttcgac gcgctggttc ttgaagtaga tggtctgctg agcgtcatcc tgaatgtggg
    11641 taatgttgcc ggcaggatcg taggtgtaat gcagattttg cagcccgcac gccttgcctt
    11701 gcggaggctt gtccggcgct gcaatggtag gtggaggcgg ctgtgggttg tcgcaatctt
    11761 ccgaaaagga cacacctcgc gctgtctttg gatccacacc tcggcgggta tacaaatgca
    11821 tcaggcgaaa cgtctcgcgg tcatagctgt aggtggtctg aataaccttc gcgtctcgcg
    11881 tcttgtaggc aatgagcatt cgctggccct tggcatcgta gtcgatgttg gcgacgccaa
    11941 cgggggttgg tgcatcgacg gatggatcga gcagcgcact cggctcggtt gcacgctcca
    12001 tccacacatc cacacgctcc agtagattgg cttcgttgaa gacctgctgg atgaccttga
    12061 agttgccacg cctctcactg ctgatggagg cgatcgattg cacgggccga ttcaacgcat
    12121 cgtagcggct gctgctctcg aaacgttcgg aatcaagttg taggttttgt gaccaatcgg
    12181 ggatcttctc gtagaggcta accagttgtc gtgtggtgcg caagaggttg cccttgaagt
    12241 cataggcctc ggtcggatga ccatcgacat tgagccgggc gctgacggca atgccagcgg
    12301 gatcgaaatg gcggtaaata cgcgtgcact ggttaaggcg ttgcgcttct cttttctgag
    12361 cctcggtcgc attggctgga ggctcgccat actcaatcct gtcgacaagg aggccgatgg
    12421 cattcggcgg atttagcgtt cgagggtctg attcagcggt gttaccgaga acgtactggc
    12481 tgatcgggcg acgcagcgcg tcatagctca tcgtgaaatt gtgacctcgg ctgtcccacg
    12541 cacggatggg cttgctggcc acgtcgttga gcatccagcg ggcaccggct tccatgctga
    12601 gttggtgtat gcggttgccg agcatgtcgt atgtgtagcg catcacaatc cgaccgaatg
    12661 gatcgccgtc ctgcaccatc gcatcgcgca cggcacactg gttgccttcg gtatccagtt
    12721 cgacgcgggt ggcgaagttc tcttcggtgc cgtcgaggtc gtgtccggga cagattatcc
    12781 ggttccgggc cacggtcagg aaatgtctgc ccagggcatc gaaatgagcg gtggttggcg
    12841 tatcggcatg ggctgcggca cccagagcag cgttacgctc atgctgtccc aaatcaccgc
    12901 cgatgcggtg cgcgtgccaa gtttgccagg tagccggctg ggtcttgaaa tattcggcta
    12961 catagccaac gatgtcgggg tcggtgcgcg gatcgccggt ctgttgattg cgaggcgcac
    13021 aggtgtcgtt gacgtcgtag gcggtctgtt gccaagagtc gaaaacgacc ttctcgtaag
    13081 tgttgttcgg atgcagggtt gccatgacac gcccggcggg gtcgtaaaac agcaccggac
    13141 ttacgcccac tttggtgccg aactcgaatc gatgggtggt gctgaaaaat ggttcgtatt
    13201 gacggactgg cttgcccttg ttgttgaaga tggtccagcc gctgcctacc caacgacggc
    13261 gaggcaggtt accagtcttc acctttgcaa catgtgactg aatccggcct ggggcgagcg
    13321 cctgatcgta taggaccacc tcatcgagca agccattgaa ttggcgatta cgttcaactt
    13381 gattgccgat acccaacttg ctcgagccga acgtcgagac aatactgccc acgacggacc
    13441 acgatgtgtc caggacgccg ttgacataaa tttgaatggt ttggccgtcg aatgttgccg
    13501 ctacgtgggt gggaacgtga gcgctcactt tgactttact ggtgacaagt acgggatccg
    13561 aatgtccagt gatcaccagc tcaagacgta cagtgccgtt ttccaggata ctcaagccat
    13621 aggttggcca ggttggggac cctgcgctat acgacttttc caggatccgc tgttgcgaac
    13681 cagtgggccc aaaccaatta atgagtgcct cgatcgttat ccatttcgga ttaagctgtt
    13741 cactatcagg gacgaccact cgcccgctgc cttgtccatc ggaaagtatc gcggcatcgt
    13801 ccacgccaag tcctgcttgc tgcaatgtga tcccggtcgg cgaacactca ccgtggtgtc
    13861 cgttgcctga ctggtccaat attctggttg attccgcaga gtcgttcaga cggtagtagg
    13921 caatgggtcg atcttctagg acatcaaccg caaatcttcc ctgatcgggc tccgcctgaa
    13981 tctttttctg aatctcgcgg ccaaatccat cggaatagct gaaggtgacc tgcagcttgc
    14041 tctcttggtt tggtgccaga tcgctgacat gggtttcacg cgtcagcgtc gcaccacaag
    14101 atggctgcca tagctggggg tcattgggat aggcccgctg ggtgcggcgg aatcgatcga
    14161 ggtcgtagac gatacgcgtg gtggcatcct gcagcagcgc cgaggcggtg gcgtgcggat
    14221 cggcgacggc gaagaagccg tcgagctggg tctgcgtgag gtcggcgaca aagccggtca
    14281 acgagtcccc ttccaccggc gcgggcagcg gttttcccat gacggcggtg ccaaccacca
    14341 ttccaaggac atcaaaggcg acctccgttt ggttgcgatt cggatcgctg acgaggcgcg
    14401 gctgcaagac acggtaatcg ttcgtgtcca cggtaaagcg gtttcccaaa gcgtcccttg
    14461 attcctttac caataggtcg tagccgtcga agtcaatgag ggagttctgg ccgaaggggt
    14521 cgcggtagcg cctcggctga aagaaatgcg cctgcgcctc ggtcagttca actggtgcgg
    14581 atacttcatt agagtgatag aacgaccggc cggaggggat ccaccagtgg ccgttgctgt
    14641 ccagatcgac ataaccacct ctgtccccac tcagtgaagg ggcgcggtca acgggaaaca
    14701 cctgcagagg atctggaatg agaacagcac tattgcgctg atacacctgt gctatcaggc
    14761 caggagtgaa ggcgagctta taactctccc cgggcaaggc gagcggttgc aagccttcga
    14821 gcggcaggag cacgctcagg ttatcgctcc ggtaaagcgt gcgcagccat tcgatgggac
    14881 ggcgacaggg atttccagta gccggcgcct catacgcaac ttcatccgtg aatttaagct
    14941 gcagacgggc cggcaaggct ggatcaggct cgacgaaatc cgaagcccga tagcgccctg
    15001 ctatcctggt gggtgtatag ccggtcaact cgtaggtgat cgcctcgcag ggcagcggtg
    15061 tgcgatgggc gtccggtgtt ttgatggcgt tggtgacacg actctccgta taggtcagca
    15121 gtggcgttgt ctggcggtca cgatcccact gttccgccag cggcgagaca cgccgaccat
    15181 agccgatcgc tgcctgcttg aggacgttgc cgaaatcatc cacttccagc gtcagcgcgt
    15241 gctggatgcg cggatccgcc gtattgcgtt catagtgata gctgattgct tcgcgtgcgt
    15301 gagtgaagaa gacggcgtgg ggattgacgc ctcgcggctg caaaggttgg attgtgaaat
    15361 tctgttcggt aacagtgtag gggatgcggg cgcgctggat ctgctctaga gtcgcaccgg
    15421 ggtgatccgc gtcattggca tacacctcct ggcgtagcat cgagcccttg agtgcacggc
    15481 aggcctcccg ttcctcttcc aaggtcaggc cggaggggat aaccgtgtca gggagcaacg
    15541 tttggaaata tgcatcgaaa agggccttgt agttctgagc gttcttctca ggggcaccgt
    15601 aatattccct cgcgaaatgc tgactgacct cgtcagtccc ctcatagccc cccgtgtgga
    15661 accaggtctt ggtgtgaacc ggtggtacgt gcgaggtggc ggcgatgttg tcactctgcg
    15721 ggaatactcc gctggcgata agtgcgccga tctgctcggt atcccactgc tcgaccatcc
    15781 cgaacccgcg gaactcgcgc tcctctccat cgaagtagcc gtggtggtag gcgtagcggc
    15841 tgacgaagcg gttgcgactg atatgatcgt aagtctcaac ccgctcaacg acatgcactg
    15901 gaaacggcag ccgcgtaatc catggttggc catcacgctt atcctgcaga tagaacttgg
    15961 tcgatggggc gaaatggacc cgaatctccg ccccgaggtt attgactgtc ttgatcagga
    16021 gatgaggctt ctgtttgccc attaggttga catagcgcat cggtcggccc gcatcgcccg
    16081 gcaacggcga tgaccagacc aggcatgcgg tgccgtttcc aagcaggtcg gtcggcagaa
    16141 tgttcaccgg gtcatcaatt cgcgggaata ccttcaagtg atacggctga ctccagctat
    16201 tacccgattg gttgaagaac agccgcaccc cgtcgcggtg caggtagatg atgtcagtgg
    16261 tgccgctgcc gtcgatgtcg gcgagacgaa tgcgtttgtg atcgaattgg tcgggattat
    16321 caaaccaagg cgcgttgtcc atcatgactt tggcgccgaa ccgaccatag cccaggtttg
    16381 gccagtagca gacttcgccg ttgcggatgc ggacgatgtc agtgagaccg tcgccggaga
    16441 gatctgccag gtagatggac tgcgttccgt caccgaaaac gatgcgcggt cctttctctt
    16501 cgtcaagcgc ttgcgcgata cgtaaggccg gaccgaaccc atcctcagcc aatgaagagt
    16561 gccaaacgaa ggcctcgtct tcactgatga gtatgtcggc atggccatcg ccatcgagat
    16621 cgacaaactt gagattagga tcgcgcatgt ctcgactgag gcgagcggtg aagaaacgga
    16681 agggctgcca gccttcaccc ttgtcatgtt catagagacc cgacataggc ccatccagca
    16741 cgaccacgtc tggcaggccg tcgccggcca aatccatgaa ctgcgcaccc ccggccaaag
    16801 caagattggg cttaagagcg acacactcca ttggtgagaa ttctccaggc cgcttgctga
    16861 tggggctgag gttgcgcttg tagaaccacg tgcctgcttg ttctgtcagg atgccgggaa
    16921 tgccttcgcc atgcagatcg gtccattgat aggccgtgcc gtctaccccg ataggtaggt
    16981 tcttcaggtt ctctgaatcc attacttcaa cagtctcttg gacgatcggc ttcgtgtatt
    17041 caaactcgac aggcggcaga ctgcccttgt catagctgcc gttggtgcgg cgatagcccg
    17101 tatgggtaac cgctgtcaaa aaggtgtaga ccgggttacg accgtctgtg tgatcaactt
    17161 cgttggaata catgaaatcg gtcgaacgca ccaagcaatc acgccccact ccagcttcgt
    17221 ccgggaagtg gtggaacatc aggacgcgct ggcagatccg ataggtgcga acctcgaagc
    17281 ccgcgcggta ggacgaaaag ggatcgggcc gcgcgggcca tgagcctgcg tcattgggtg
    17341 ttggcgcctt ggcatcgtgt tcgccatagt cgaagacgac ttcaaagtgc cagacgttgc
    17401 taccatcagg tacatgggca tccggcggtt caggccagac ggcatccgac ttcaacactg
    17461 gaaaatacgg cgatccgttg ccatagcgta tgtgcttgag gtagcgctgc gccgaacgtg
    17521 tctgatcgct ccgatagcgc tcgtgcgctt tgccgaggct cttttgcgat gagtcttgaa
    17581 agacgttggt cgaatcctct gtcttgtagc catagacgat gacgttgccc ttgtcatcgt
    17641 ggctctggca gatcagccaa ctgaaaatgc gatttgtgtc agaaggatcc gcgatgcggc
    17701 tgtccggcga ccttccgtac caggtcgtga tgttgtcctt ggaaatggag cgccagaaca
    17761 cgtcagtcgc gtcattgata ttcgtccagc gttcgatact cgcaaacaag ccctcgatac
    17821 gcgggcggta gcgacggata cggtaggttt tggcgtcaat tgttctatct ggaagttctt
    17881 ctcgcgccca atgcttattg gcatcctgca caagcacggg caccaggtct tccgcgccag
    17941 acagaatgaa gacatcggat tccttggcat ccaggtactg aggcaggcct ttctcggttc
    18001 tgcgtgtgat cgacggcagc gagaggctcc agccgaagcc gaatgggctg ttccccgcac
    18061 ctgagtcgta ggacagcgag agttgtggac caaagcccga gcgtccgggt gaggtggcga
    18121 tcggcacggt cattgagccc gtaccggtga cgggattggc ggcgaacttc tcgccgatgc
    18181 cacggatcgc cccgccacct ttcggcaagg tgatggcagg agcagaaact tggaaggact
    18241 tttctgcgga gttgccgtcg ctgctctccc gcttgagctc ggccattcct taccctctat
    18301 attcggcgaa aagtggccca accgtgcctg aatctcatgc atcggtcaag atcattaatt
    18361 acgtgtattt acaaagtgac gaaaacacga ttgcctgtga tgcgtgctaa gaaaaaatat
    18421 caggaactat gagtaaggtt ggacctccag actaactgtg acggggtggc gagggatcct
    18481 tgatgacggc ttgcgggtga gaggactgtg actgcaacgc agtgggcaca tgtctgagcc
    18541 caaatggtcc gtaccgttgt ctctacacat tcacggcagg gctatcgtgc gaccgccgcg
    18601 gtgtgccgca cctgggtcat gcgtccccca aaagtatttt cgaaggcgac gctcctgcaa
    18661 ttcccgaata tctggttcac actaaggatc tgggctcgaa attgtaatgg cttcttgact
    18721 gggcggacga tctcttggga tagccgcgtc gtcctatgag ggaatggcgc aaccccgact
    18781 cagctggaat cacgggcggc cccaggtcga tgccagttcg gacggtcttg cggttcaggc
    18841 cgaatcgctg ggtggcccct ttgaatccgg acgtctcgct attgcaggat gttgagtggg
    18901 ttttgggaga acgatggtgt cgtgcggcaa tgtgccggtt tcccggttcc ttcgtcgaga
    18961 tcaaatttca tgtgatacca tcggatgatg gctcgtgacg gaaaccatgc agggagccaa
    19021 ttctcaataa tatattgagt gtagacgatc gttgatcgag gtgatccccg attctctgtt
    19081 tcagcctatt aatgtgctgg aatttcaacg tctgttcgac ctacatgctg gctcagacgc
    19141 gcatttcctc tgtttcgaaa aagaactgca ccaactttgt attccctctt ggccacagta
    19201 agcgcagcct ggtggtccga ctcctccgca gacgttcttc agttcagcat gctgactacc
    19261 accgcgacgc gctggttggt cgtccacctc tcaattcgtt cggcgattct gccgccatct
    19321 cgccatcaac tcggtcctcg tccagactct gtgcaggaat ggtctcaaaa gcaagtggtg
    19381 catttcggtg ttcgcaagat tagcagagcc aacaaatatg tcagtcgatc cagtaacaaa
    19441 tttggtgaat ttagatctct acttctgggt agccaacgag tcagacaatt ttgttggtaa
    19501 aattgttgcc ggttaggcag cccaacggaa ggggatcgac aattttgttc gcatgaggat
    19561 caaaattacc acgtatggga ccaaacaaat ctggcggttt tgtcgccaaa attgttgaag
    19621 aggacgccta tgtgccggga caaaatcgtg acaagtcaat gacggaaggg ctgtgaaaga
    19681 cgttgaaaaa tatggaactt tgtgaagtct ggcattttaa atatgtccgg gaaacccgca
    19741 tgaaaatagg cattttcaga cccccgttct gtttaggaaa ccgctgctct atccaactga
    19801 gctacggggg cgtcgtcgta cgata
//
LOCUS       DAOQPD010000074        19472 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1400_length_19472_cov_19.718597, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000074 DAOQPD010000000
VERSION     DAOQPD010000074.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 19472)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 19472)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19472
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1400_length_19472_cov_19.718597"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            380..2374
                     /locus_tag="PK063_14715"
     CDS             380..2374
                     /locus_tag="PK063_14715"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase VI subunit B"
                     /protein_id="HMZ98352.1"
                     /translation="MTAVEMGARQREISVSEFFTKNRHLLGFDNPRKALLTCVKEAVD
                     NSLDACEEAGILPDVTVKLEVVANGPAPVAPSQATRFRITVTDNGPGIVRQQIPRVFA
                     KLLYGSKFHRMRMSRGQQGIGISAAGMYGQLTTGKPVKVISRTGPRAAAHYFEVQIDT
                     KKNEPLVHENKQIEWSQPQGTEVVLEVEGRYQKGRASVDEWLEQTSIANPHVRLTYHT
                     PEGEQRSYPRTYHELPPSPKEIKPHPYGIEFGALLKMLQDTKSHTVASFLASDFCRVS
                     PALAEEICKAAKLSPTTKPRDVKPQAAETLYKTIQTTKIMAPPTNCISPIGEKAILSG
                     LYKQIKGEFYTAVSRPPAVYRGYPFVIEAGLAFGKGPEEPSKPQHAAVPLAEGEDQGN
                     DTEQARVIRYANRVPLLYQQSACATFKAVLSTTWRNYGVSQSRGALPAGPMVIFVHMA
                     SVWVPFTSESKEAIADYDEIQKEITLALREAGRRLGIFLRRRERAASEFRRRNIFELY
                     IEEVVAACNRLKGGNLPTEKLKEQLHKIASSRTGGLKTDEALGKTGAGPEGLPHSIIV
                     TAEGIEGEREVAENVPEPADGPVSAASPESAAPAKVPKKGRRAVATAPTSKKSRPASN
                     AKRKAGQQELFAEAADGKHAPARKTPSKPSKTATGTRKRK"
     gene            2383..3489
                     /locus_tag="PK063_14720"
     CDS             2383..3489
                     /locus_tag="PK063_14720"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HMZ98353.1"
                     /translation="MAQAKPKKNGAVAKKLVGMADVVISAAQRSKDPTFEIPIRALSN
                     VSFNPRKGLIEMGEKKQARTFFNVGMAKKFMQTMLVADALAELQQADLTTSLREIYYR
                     TKHTIQDSHENTFDTQDESDPIIEDLEVSLIALREELHVRAENSGSIVGPVVFGDDGD
                     RVDCAKLGKGGYSVPSIVEPEYLEIRRCTADFLLLVEKGTQWNRLSEDKFWRRYNCVL
                     LTGNGQPPRGVRRLARRLHEEHKLPVYVLVDNDPWGYYIYSVVKQGSINLAFESQRMA
                     IPKAKFIGLSSADPERYELPRNVGIKLNEKDVTRAKELLNYQWFQKPAWQQEIKRMLT
                     SGLKYELDALANKDFQYLTKKYLPRKLKEKDWLD"
     gene            3509..3934
                     /locus_tag="PK063_14725"
     CDS             3509..3934
                     /locus_tag="PK063_14725"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98354.1"
                     /translation="MMQQGGRTWSIQRSVLRISVCLLLLAPALVTAQSLPPSSNQLNQ
                     QNQPGSNLQAPGTIPIPNPLAQQSAISSTASGASAPQSNTIPSSQGKSFGTIGQGLPG
                     MTSGPTLTAPMGSQDPSARYMRPTVIPPLFCDPAINIPC"
     assembly_gap    3938..4037
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(4217..4648)
                     /locus_tag="PK063_14730"
     CDS             complement(4217..4648)
                     /locus_tag="PK063_14730"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98355.1"
                     /translation="MRSALALLLIVLTAGFTLGCSTPSASRLTGAIRYFNIRSEIAPR
                     HLIAQIGDEIRWQNLNPHPVTLRMLEDSDPALLACDKGFKQFGVIQDTVTIAPLQSVS
                     LCFLKPGTIRFNVWLDADNPQGAMTPTGTIRVEPSPVRRNS"
     gene            4789..6111
                     /locus_tag="PK063_14735"
     CDS             4789..6111
                     /locus_tag="PK063_14735"
                     /inference="COORDINATES: protein motif:HMM:NF020390.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1800 domain-containing protein"
                     /protein_id="HMZ98356.1"
                     /translation="MGLTFDEARHLLSRTGFGGTPEEIRAFMAFDRPDAVKQLLTIPT
                     HKASTPPPAWIHQLPPLPRLRKFWTDRERKAFHEQLKVQGHELKAWWYRELITTRHPL
                     LERMTLFWHNHFTSSLHKVRWPAFLYQQNVLLRLHALGSFRTLLQSIAKNPAMLLYLD
                     THTNRREHPNENFARELFELFTLGEGHYTEQDIKQAARAFTGWHLDHHTGAFRMDLRH
                     HDEGQKEVFGRKGHFDGDDILSLTLEQPHVARYLVRKLWREFISEQPDAVAVERLADS
                     FRRNKYETVDLLKELFLTEAFWAPENRGALIKSPVELIVGTMRLFDLPFDDVTLQVVY
                     GRRLGQDLFDPPNVKGWPGGLRWITTSTLLSRTQLLQRAIRGHETGHLHGMTDMKQAQ
                     GAMWLATETTEVVQATLLPFAPVQPLTAGDDRGQAVHHLVLDPVYQLK"
     gene            6119..7330
                     /locus_tag="PK063_14740"
     CDS             6119..7330
                     /locus_tag="PK063_14740"
                     /inference="COORDINATES: protein motif:HMM:NF019040.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1501 domain-containing protein"
                     /protein_id="HMZ98357.1"
                     /translation="MTTWSIHRRTFLEAAMALPLLWLRPGWLSLLRAADTSNFSERSH
                     KRERILLLVELQGGNDGLNTVIPYDDAAYYRARPQLAIPRDQVRQLTPKLGLHPALSP
                     LMPLWERKELAWLQGVGYPKPNRSHFRSIEIWDTASDSEEVRDKGWLSGLFAQYPLPA
                     GFTAEGVLLGKGDAGPLSGGTTRTMALHDPAQLFRQAGALKPLSASTTNRALAHILEV
                     RREISQAAIDVQQRVQEAPPFAMDFPTHKFGKQLEVAARLIAAKLPVAVIKVTHGSFD
                     THAGQLSTHHRLLEELTQGLMAFRAAMEQRGLWSQVLVMTYSEFGRRVGENASHGTDH
                     GTAAPHLFMGGRVRGGLYGAPCSLTDLEGGDLKYTLDYRSLYATVIEQWWGLPAVSFG
                     GGRYPVVDCLT"
     gene            7398..7763
                     /locus_tag="PK063_14745"
     CDS             7398..7763
                     /locus_tag="PK063_14745"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98358.1"
                     /translation="MLRELLRTGVAVALLVSVTLLPALTSRIQAEEGGASNPSSVTQS
                     PAPRPGALQQTPAPVEPSLPLLMAEGSNSCEIVSCGMGIKQTCQITCPADKTPKCSCD
                     CERSFGPMCMDYKANCRCE"
     gene            complement(7779..7979)
                     /locus_tag="PK063_14750"
     CDS             complement(7779..7979)
                     /locus_tag="PK063_14750"
                     /inference="COORDINATES: protein motif:HMM:NF015821.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor YacG"
                     /protein_id="HMZ98359.1"
                     /translation="MSAIQTSPHRCPECHQATAWKDNPWRPFCSERCQLIDLGAWAGE
                     QYRVPGPSLSVGGTESFSPDSE"
     gene            complement(7985..8686)
                     /locus_tag="PK063_14755"
     CDS             complement(7985..8686)
                     /locus_tag="PK063_14755"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HMZ98360.1"
                     /translation="MPTLSRAWCSLALASALTACAAPSSQGLRQAVTPIPDCCRASHS
                     DTRQQAIVRTAVNLVGATTIESQGRRISYDCAGVTRAIYLAHGIDLYSDGSADGRTNG
                     VGLIYNHIRKNGRLHRGPVVQAGDLVFFDNTWDFNGDGLVNDPLTHVGIVEQVEQDGT
                     IVFISRVAGAIERYRMNVAHPHIHRTADGRLLNDYMRRKHWRDGEHTAYLTGELFAAF
                     GTRVIDSPSIPPAPR"
     gene            complement(8866..10518)
                     /gene="pgm"
                     /locus_tag="PK063_14760"
     CDS             complement(8866..10518)
                     /gene="pgm"
                     /locus_tag="PK063_14760"
                     /EC_number="5.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004614 - phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucomutase
                     (alpha-D-glucose-1,6-bisphosphate-dependent)"
                     /protein_id="HMZ98361.1"
                     /translation="MAQHPRAGQPAQPEQFVNLARLEQAYYQETPDPADVQQRVSFGT
                     SGHRGSSLKRTFNEAHILAITQAICEYRIKAGTTGPLFVGKDTHALSAPAQRSALEVL
                     AANGVEVRLDKDDGYTPTPVMSHAIIQTNRDRTSGFADGIIVTPSHNPPEDGGFKYNP
                     PHGGPADTDVTKAIENRANELLAANLQGVKRMPYEQAIRAVSTTRYDFAGTYIADLAQ
                     VVDLDRIKAANLRLGVDPLGGAAVAYWRPLAERYGLNLEIVNASVDPTFRFMTLDWDG
                     KIRMDCSSPYAMASLITLKNRFDLAFGNDTDTDRHGIITPGAGLMNPNHYLAAAISYL
                     FTHRPGWKSSAAVGKTVVSSSIIDRLVRSLKRRLVEVPVGFKWFVPGLSDGSLGFGGE
                     ESAGAAFLRRDGTTWVTDKDGIIMNLLAAEMLAVTGKDPAQLYGELTAQLGEPVYERI
                     DAPATRAQKAALQKFSPQQVRSKELAGEPIIAMLTEAPGNKASIGGLKVTTANGWFAA
                     RPSGTEDVYKLYAESFKGQAHLLQIQEDAQALIKQVFSSAGA"
     gene            10675..10941
                     /locus_tag="PK063_14765"
     CDS             10675..10941
                     /locus_tag="PK063_14765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HMZ98362.1"
                     /translation="MPNITLLHSPTCGACPSAKRLWKELRVKYSFSYREVDITTPDGQ
                     ELANRHSVRAVPATIIDGRLTFVGVPPRQSAEKALQLKMKPQGA"
     gene            10954..11118
                     /locus_tag="PK063_14770"
     CDS             10954..11118
                     /locus_tag="PK063_14770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014961085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98363.1"
                     /translation="MTVPDDDDFELPILPMIDKGPPPECGTCGDPMKFIDGDWACVDC
                     NGELLGPETG"
     gene            11215..14445
                     /locus_tag="PK063_14775"
     CDS             11215..14445
                     /locus_tag="PK063_14775"
                     /inference="COORDINATES: protein motif:HMM:NF024117.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HMZ98364.1"
                     /translation="MLRLVTGPFHPTLETRLVQDLRALKSKDRLASLAIIVPSDQLRR
                     SLKRLLILQEKLSLLNVHILSFHQLALHVDRERRTAEGAAPGRQMDLVSDVFFEHLLR
                     HIGQRRMPHTESLRLSQLPHGAWPALWASLRDLKDATVDSAVAVRAVEEGQFAPEEGE
                     KLKGLFTLYAAVREGSAALGVGSPDDLASLVTPFVPTSPFLRGLHELWYYGSYDLTQT
                     QLTLLESLAATLPVTVYFPVDAQPAYGFARQFLERHLYPMAGTSDASMLDSPEPSGSD
                     GTRANVSVEVRNAAGIDDELTLVCKQILTLVETHGYRFEEIGVVGRTLVPYQSTLVRL
                     FDQHRIPFTSTAAVPLLREPAMKTLLHLARLKGNGLHRSAMLDVITSPWNRRLTAPQG
                     GEPPRPDLWRLAVHALGITKGEEEWRRLAQLGRLEAWAGTGDESSEDPLDALSIDGPQ
                     LRLLWDCVSPLIDGVTGLPESGGYGGLTDAFCALAEDHLSIPLDMSDSIDAATQSQGI
                     TDVTEALVGALAQLRELDRLDVRITWQEWTDTFEGILERTTYALTSPSQQGVQVLDAM
                     AARGLGFRALFVVGMNEKMFPRYIHEDGFLRDSHRLVLSETLGYKIDQKLQGYGEEAL
                     LFELLRASARERLYLSYQRADAAGRPLAPSGYLDGMGVVPHAADAQSLFAVPRRWKDR
                     TALPLFIPPLLTREEHTVSSVLHGRDAASLLNAGGREGELFAHGLATQALIESGVPAL
                     SVYDGLLTDATSHWNRIRERGISPTALETYARCPFQYFSAQVLDLDAVRQTVSMELSP
                     PAMGQLCHDALRLCYLALIRQGWGTAAASAAVVTAEVTRAVTQAFAAYAMTHGTGYAL
                     TWQLAQDTVRHLVEAMVRFDCEAAAASGFIPVECEIDAKGVLPDGTAGEAIPLRGRWD
                     RLDRHPVSGALRVIDYKYRANDRIDAKDRQLLQAAVRAQRLQPALYTLMAVDGPGEQP
                     HGPQPEQVEFLYLLPQGMPMVERASFPASCWQGPSGPMLSRTVQLLVDGIRSGRHFIV
                     PDTAHCDHCEFATACRKAHQPSLWRTRRSSLAGALRALRFEKVARD"
     gene            14438..17830
                     /locus_tag="PK063_14780"
     CDS             14438..17830
                     /locus_tag="PK063_14780"
                     /inference="COORDINATES: protein motif:HMM:NF012789.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HMZ98365.1"
                     /translation="MTEQSTIPDQAAREAAATTFDRNVVVIAGAGTGKTTLLVNRLLY
                     LLMRRADPLDLSRIVALTFTNKAATEMKLRLRERLRSLVSLEGRDNPATGSGTVSIAD
                     LRLRFGWTTDEIVARAEAALRDIEKAQIGTLHSFAAHLLRLYPIEAGVSPTFQTDEDG
                     SRFEEHFTAEWELWLDRELGLSGSDHGRWRLLLAAFSLEDLRQLAYSLHSDLIDLDGL
                     RAQITENGLNQVLRDWFAERKAQAARLLARYDGPKRRKIESMLATIVDLFDLLLDDGL
                     DGIHALPPDSHELLAKELGKAPNGWVEEDFEEAESLQRIANRLLKVDQGLLGQLLEVL
                     APFIRAVRKSFLDTGWLSFDGLVGKARSLLRDYPMIREQLKRDYRALLVDEFQDTDPV
                     QYEIVLYLAERLGEQSTSWRTIELESGKLFIVGDPKQSIYAFRRADIEAFDHVVERLE
                     QGGALRCELATNFRSHAQVLDLVNGVFNRLLVAQPSVQPPNVPLTAQPNRSSQFRDTG
                     VELRLVQSEEEGDLDSAAATRVEAEHLASMISRWLTPTEPGGEAAVAGTRLRPGHIAL
                     LFRKLTQAEEYLEALRRHDIQYIIDGEKHFYRRQEVIDLVNILRCIENPHDRIALVGV
                     LRSPIGGLPDSALVSLQEAQAWDYREPGPLSKWTSPHVEPLRRLYAVLARLHEAAPRC
                     PLPQVMDLVFQQLPLLELAAASIHGEQAVANLLKIRQMAADLADRPALTLNGFVELML
                     ERLREQPDEAESALSEDTLDAVRVLTIHKAKGLEFPLVILAGLHHGDGAGRGPARPQI
                     WHDWSTGTQGLDFGGLCTAGAVLVAEKARIREQAERRRLFYVGMTRARESLVLSGALP
                     KRRVRGALLDLLAQAAGAEFNGIGEGGLSVGGVGLRHTILKGEDRFPSRERPQPTMLE
                     ETAVDQALCDRWVQRDRVWEEHRSQSLIISPSDFIRKPAPLPFSNIQPRQGRGSTSGT
                     AIGTIVHRVLQYWDFTADAERQVAAISSASLAIEEQESTTRQAIVEDVQALLHIFIQS
                     PAYARLRQATVIGREMPFLIPWQDGRQILEGAIDILYRIEGKLWIADYKTDMIPLDQV
                     TGRADLYREQARLYREAVTQSLGEPVAGFEFIFLRLGVTVPV"
     gene            17846..18250
                     /locus_tag="PK063_14785"
     CDS             17846..18250
                     /locus_tag="PK063_14785"
                     /inference="COORDINATES: protein motif:HMM:NF024806.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ98366.1"
                     /translation="MKHLGWMIMVIVTIVGCAGPRKAEVRPLHAPTGTPEAVSRQLEQ
                     GNQLLSKEDWAGARDAYLATIQADQSLAEAHYNLALALEKLGEKAEARKHYVAAANLA
                     PGNKVIWDAPPLRKYDSELTLGKKSWMDANPK"
     gene            complement(18276..19109)
                     /gene="lgt"
                     /locus_tag="PK063_14790"
     CDS             complement(18276..19109)
                     /gene="lgt"
                     /locus_tag="PK063_14790"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HMZ98367.1"
                     /translation="MLPWLHAIPYPDIDPVFLRLGPLQFRWYGLMYLIGLTLAYFIIE
                     ARARAQKLPLNKDQVYDMIVYAAVGVFAGGRLGYVLFYNLSYYLENPLKIFAVWEGGM
                     SFHGGLIGTIVALILFAKRQGMTVLTIADLAAGVTPVGLGLGRIGNFINGELYGRPTD
                     VDWCMVFPAGGMVCRHPSQLYEAFLEGLLLFTVLWLITRRLPPSGTVFGSFLVGYGLC
                     RIVVEFFREPDAQIGFIVGTISMGQMLSIPMIVAGAVILAIASQRKRPLRSDSSSTAT
                     L"
BASE COUNT         3917 a         5491 c         6009 g         3955 t
ORIGIN      
        1 gagatctccg ccgtatctac ctctcctcgg taggtgcgtc ctcctcccac ccaaacctgc
       61 cttctcttcg caagcccggt tccataacac tgagtcgtgt cacttccgcg acaggttgcg
      121 catcaggtgc ggcgaccgga atctcctcaa ggcttgactc tccgcagcgt tccctgtaaa
      181 cgacgaggag gatacgtatc gcgcctgtcg ctgcgccgcg ccaattctct gaatcccttg
      241 cttgagaggt tgaatggcca ccaagagatc atcgccacgt gccgagtctt ccacatccgc
      301 gcctgcctcc gaatccactg aatctgaatc ggccgtctca cgaaacaaat ccggcgctgc
      361 acaaaaatca gcgcccgcgg tgacggcagt ggaaatgggc gcgcggcagc gtgagatctc
      421 cgtgtccgaa ttcttcacga agaatcggca cctgctggga ttcgacaatc cgcggaaggc
      481 gttgctgacg tgcgtgaaag aagccgtcga caactcgctt gatgcctgtg aagaagcggg
      541 catccttcct gacgtgacgg tgaagctgga agtggtcgcg aacggaccgg ctccggtcgc
      601 accaagccag gccacccgct ttcgcatcac cgtgaccgac aacgggccgg gcattgtccg
      661 gcagcagatt ccgcgtgtgt ttgcgaagtt gctctatggc tccaaatttc accgcatgcg
      721 gatgagccgg ggacagcagg gcatcggcat ttccgcggcc ggcatgtacg gccagctcac
      781 gaccggcaag ccggtgaagg tgatctcccg caccggaccg cgagctgcgg cccattactt
      841 cgaagtgcaa atcgacacca agaagaatga accgctggtg catgagaata aacagatcga
      901 gtggtcgcaa ccgcaaggta ccgaggtggt gctggaagtc gaaggacggt atcaaaaggg
      961 gcgcgcctcc gtggatgaat ggctggaaca gacatcgatc gccaatccgc atgtgcgact
     1021 gacgtatcac acgccggaag gagagcagcg aagttacccg cgcacctatc atgagttgcc
     1081 gccgtcgccg aaggagatca agccgcatcc ctacggcatt gaattcggtg cgttgctcaa
     1141 gatgttgcag gatacgaaga gccacacggt cgcatcgttt ttagccagcg acttctgccg
     1201 ggtgtctccc gcgctggccg aggagatctg caaagccgca aaactgtcgc ccacgaccaa
     1261 accgcgcgat gtcaaacccc aggcggcgga gacgctctac aaaaccatcc aaacgaccaa
     1321 gatcatggcg ccgccgacca attgcatttc cccgatcggc gaaaaggcga ttctttcggg
     1381 cctctataag cagatcaagg gcgagtttta cacggcggtc agtcggccgc cggccgtgta
     1441 tcgcgggtat ccctttgtca tcgaagcggg gctggcgttc gggaaagggc cggaagaacc
     1501 ttcgaagccg cagcacgccg cagttcccct ggcggaaggg gaagaccagg ggaatgatac
     1561 cgagcaggcg cgggtgatcc gctacgccaa tcgggtgccg ttgttgtatc aacaatctgc
     1621 ctgcgcgact ttcaaggccg tactcagtac cacttggcgc aattatggtg tcagtcaatc
     1681 ccgtggcgcg ttgcctgcgg gaccgatggt gatatttgtg catatggctt ccgtttgggt
     1741 gccgttcacc agtgagtcga aagaagccat cgccgactac gatgagattc agaaggaaat
     1801 cacgctggcc ctgcgcgaag ccgggcggcg gttgggaatt ttcctgcgca ggcgcgaacg
     1861 tgccgccagc gaattccggc gccgcaatat tttcgagttg tacatcgaag aggtggtggc
     1921 tgcgtgcaat cgtttgaagg gcggaaacct gcccactgaa aaattgaaag aacagttaca
     1981 caagatcgcc agttcacgaa cgggtggtct caagacggat gaagcgctcg ggaaaaccgg
     2041 cgccggtcct gaaggtctgc cccattccat tatcgtcacg gcggaaggca tcgaaggcga
     2101 gcgtgaggtc gctgagaatg ttcccgagcc tgcggatggt ccggtgagtg cagcctctcc
     2161 tgaatccgct gctccggcaa aagttcccaa gaaaggcagg cgagcggtcg cgaccgcgcc
     2221 tacatcgaaa aagagtcggc cagcctcgaa tgcgaagcgc aaagccgggc agcaggagct
     2281 gtttgctgaa gcagctgatg ggaagcacgc gccggctcgc aagacaccct ctaagccctc
     2341 taagacggcg acaggcactc gcaaaaggaa ataggacagc ttatggcaca ggcgaaaccg
     2401 aaaaagaacg gtgcagtggc aaaaaagctc gtcggtatgg ccgatgtcgt gatctcggcg
     2461 gctcaacgat ccaaagatcc gacgtttgag attcccattc gggccctgtc caacgtctcg
     2521 ttcaatcctc gtaagggttt gatcgagatg ggtgagaaaa aacaagcccg gacgtttttc
     2581 aacgtcggta tggccaagaa gttcatgcag acgatgctgg tggcggacgc attggctgag
     2641 ctgcagcagg ccgatttgac tacgtcgctg agggaaatct actaccgcac gaaacatacg
     2701 attcaagatt cgcatgagaa cacattcgat acgcaggatg agtccgatcc catcatcgag
     2761 gatctggaag tgtcgctcat cgcgttgcgt gaagagttac atgtgcgagc ggaaaacagc
     2821 ggaagcatcg tggggccggt tgtcttcggc gatgacggcg atcgggtgga ttgcgctaag
     2881 ttagggaagg gcggctattc cgtcccctcg atcgtggagc cggagtattt ggagatccgc
     2941 cgctgcacag ccgatttcct gttgttggtg gagaagggca cgcagtggaa ccgcttatcg
     3001 gaagataaat tctggcggcg ttacaactgt gtgctgctga cggggaacgg gcagccaccc
     3061 cgcggggtgc gccgcctggc gcgacggctt catgaagaac ataagctccc ggtgtacgtg
     3121 ttagtcgata acgatccctg gggttactat atctactcgg tggtgaaaca ggggtcgatc
     3181 aatctcgcgt tcgaaagcca gcgcatggcc atccccaaag cgaaattcat cggactgtcc
     3241 agtgccgatc ctgagcggta cgagttgccg cgcaatgtcg ggatcaagct caatgaaaaa
     3301 gacgtgaccc gcgccaagga acttctgaac taccaatggt tccagaagcc ggcctggcag
     3361 caggaaatca aacgcatgct gacgagtggc ctcaagtacg aattggacgc gttggcgaat
     3421 aaggatttcc aatatctgac caagaagtac cttccgcgca agctgaagga gaaagattgg
     3481 ttggattagt gtgcgaaggg agcgcgatgt gatgcagcaa ggcggtcgaa cgtggtcgat
     3541 tcagcgatca gtactgcgta tcagcgtatg cctgctgctg ttggcgcccg ctctcgttac
     3601 ggcgcaatcg ttaccgccgt cttccaacca gttgaaccaa cagaatcagc cgggatcaaa
     3661 tctgcaggct ccgggcacca ttccgattcc caatcccctc gcgcagcagt cggcgatttc
     3721 atccacggca tcgggagcca gcgcgccaca aagtaacact atcccgtcca gccagggcaa
     3781 atcgtttggg acgatcggcc aagggttgcc gggtatgacg agcggcccga cgctgactgc
     3841 gccgatgggg tcgcaggatc cctccgctcg ctacatgcgg ccgaccgtga tccctccgct
     3901 cttctgcgat cccgccatca atattccctg ctgagcannn nnnnnnnnnn nnnnnnnnnn
     3961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4021 nnnnnnnnnn nnnnnnngac cgtgatccct ccgctcttct gcgatcccgc catcaatatt
     4081 ccctgctgag cagctctgtg cagcgctggt acgtcgtgag gctcgcgttc gtcgagcatt
     4141 cgcgatgtcg tgatgccttc gaatgtaatg tggaaaggcc gaacagttct ggggctgagg
     4201 cgttaggcga aggagttcaa gaatttcgcc tgactggcga aggctcaacg cggatagtac
     4261 cggtcggcgt catggcgccc tggggattgt cggcgtcgag ccagacgttg aagcggatgg
     4321 tgccgggctt caggaaacag aggctgaccg attgtaatgg cgcgatcgtg accgtgtcct
     4381 gaatgacccc gaactgcttg aatcccttgt cgcatgccag caacgccggg tcgctgtctt
     4441 ccagcatccg taaggtgacg gggtgtgggt tcaggttttg ccaccggatt tcatcgccga
     4501 tctgagcgat caaatggcgc ggcgcgattt ccgaacggat attgaagtac cgaatggctc
     4561 ccgtcaggcg ggacgccgag ggtgtgctgc acccgagagt gaaaccagcc gtgagtacga
     4621 tgagcaggag tgccagcgcg gaacgcatgg ccgatcctac aaaatcgacg gagccgttct
     4681 ctactcggaa tgttacgagg cgcagtggac ggaatggtac cggtcaaccg aatgagcact
     4741 ccggcgttgt cgtaaagagc gacagattga ccgtggagag catcttccat ggggctgacc
     4801 ttcgatgagg ctcgtcatct gctctctcgc accggcttcg gtggaacgcc ggaagagatt
     4861 cgcgcgttca tggcattcga ccggccggac gccgtcaaac agctcctgac cattcccacg
     4921 cataaggcct ctactccgcc tcccgcttgg attcatcaac ttcctccgct ccccaggctg
     4981 cggaagttct ggactgaccg cgagcggaag gcctttcacg aacagctcaa ggtacagggc
     5041 catgaactca aggcctggtg gtaccgcgaa ctcatcacga cgcgccatcc gctcttggag
     5101 cgcatgaccc tgttctggca caaccatttc acgtccagct tacataaggt ccgatggccg
     5161 gcatttctgt atcaacagaa cgtgctgttg cggctccatg cgttgggatc gtttcgcacc
     5221 ttgctgcagt ccatcgcgaa gaatcccgcc atgcttctgt atctcgacac acacacgaat
     5281 cgccgggagc atcccaatga gaattttgcc cgggaattgt tcgaactgtt tacccttggt
     5341 gaaggacact acaccgagca ggacatcaag caggctgcac gcgcgtttac cggctggcac
     5401 ctcgaccacc ataccggtgc gtttcgcatg gatctgcgac accatgacga ggggcaaaag
     5461 gaggtattcg ggaggaaagg gcattttgat ggagacgata ttctctcgct gacactggag
     5521 cagcctcatg tggcccgcta tcttgtcagg aaactgtggc gtgagtttat ttccgagcag
     5581 cctgatgcgg tcgcagtgga acgtctcgcc gactcattca gacgcaacaa gtatgagaca
     5641 gtcgacctgt tgaaggaact gttcctgacc gaggcatttt gggcgccgga gaatcgaggc
     5701 gccctgatca agtctccggt tgagctcatc gtggggacga tgagattgtt cgaccttccc
     5761 tttgatgatg tgacgttgca ggtcgtgtat ggccgcaggc tgggacaaga tctcttcgac
     5821 cctccgaacg tcaaggggtg gccgggcggc ctgcgatgga ttaccacatc aaccctgttg
     5881 agtcgcacgc agctgctgca gcgggcaatc cgtggccatg agacaggcca cctgcacggc
     5941 atgacggaca tgaagcaggc tcagggggcg atgtggctcg cgacggagac aaccgaggta
     6001 gtccaagcga cgctgcttcc ctttgcgccg gtgcagccgt tgactgcggg ggatgatcgc
     6061 gggcaggccg tgcatcacct ggtgctggac ccggtctacc aattgaaatg aggctgccat
     6121 gacaacgtgg agcatccatc gacgcacatt cttggaggcc gccatggcgc tcccgcttct
     6181 gtggttgcgc ccgggttggt tgtcgctgct ccgggcggcg gatacaagta atttctcgga
     6241 gcggtcgcac aagcgtgagc gtattctgct gctggtggag ctgcaggggg gaaatgacgg
     6301 tctcaacacg gtcatcccat acgatgacgc ggcgtactac cgggcgagac cgcaactggc
     6361 aattcctcgt gatcaggttc gacagctcac tcccaaactt ggtctccatc cagccctgtc
     6421 gccgttgatg ccgctgtggg aacgcaagga gctggcgtgg ctccaaggcg tcgggtatcc
     6481 caagcctaat cgatcccatt ttcgttccat tgaaatctgg gacacagcct cggatagcga
     6541 agaggtgcga gacaagggat ggctgtctgg gctgtttgca cagtatccgt tgccggccgg
     6601 atttacggcc gaaggcgttc tgttgggcaa gggagacgcg ggccccctga gcggaggcac
     6661 gacgcgcacg atggcgctgc atgatcctgc acagttgttc cgtcaggccg gtgcgctcaa
     6721 accgctgtct gcgtctacga cgaatcgcgc actcgcccat attctggagg ttcggcggga
     6781 gatctcccaa gcggccatcg atgtgcagca acgtgttcag gaggcgccgc cgttcgcgat
     6841 ggacttcccg actcataaat tcggaaaaca actggaagtc gcggcccggc tgatcgctgc
     6901 gaagctgccg gttgcggtca tcaaggtcac tcacggcagt tttgataccc acgccggtca
     6961 actgtctacc catcaccggc tgttggaaga gctgacccaa ggattgatgg cgttccgcgc
     7021 ggcaatggaa caacgaggac tctggagtca ggtgttggtg atgacctatt ccgagttcgg
     7081 ccgccgggtc ggggagaatg ccagccacgg tactgatcat ggcaccgcag ccccgcatct
     7141 cttcatgggc gggcgcgtca ggggcggctt gtatggcgca ccgtgttcgc tgacggacct
     7201 ggaaggcggc gatctgaaat ataccctcga ctaccgcagt ctgtatgcga ccgtgattga
     7261 acagtggtgg ggcctgccgg ctgtatcatt cggtggcggg cgttatccgg tggtggactg
     7321 cctgacgtga gtgggcggga cttgatttcg cgcggaattc ttcctatcct gcggccctct
     7381 gaaaggaagg tgacgtcatg ctgagggaac tactacgaac cggtgttgcg gtggcgctat
     7441 tggtgtcggt cacattgttg cccgcgttga cgtcacggat ccaggcagaa gaaggtggcg
     7501 cgtcgaatcc ctcgtccgtc acgcagtctc cggcaccccg cccaggggca ttgcagcaga
     7561 cgcccgctcc ggtggaaccg tcattgccgc tcctgatggc cgagggatct aattcctgtg
     7621 agatcgtgtc ctgcggcatg ggcatcaagc aaacctgcca gatcacctgc ccagccgata
     7681 aaacgccgaa gtgcagttgc gattgcgagc ggagctttgg tccgatgtgt atggattaca
     7741 aggcgaactg tcgctgcgaa tgaggtaggc tgcctcggct actcactgtc cggcgaaaac
     7801 gattccgtcc cacccacgct caggctaggc cctggcacgc ggtactgctc tcctgcccag
     7861 gctcccaaat cgatcagttg gcagcgctcg gaacaaaacg ggcgccaggg attgtccttc
     7921 caggcggtgg cctggtgaca ctcgggacaa cggtgcggtg acgtctggat ggcggacaag
     7981 gctcttacct tggtgcaggt ggtattgagg gagagtctat cactctcgta ccgaaggcgg
     8041 caaacaactc gccggtcagg taggccgtgt gctctccatc ccgccagtgt tttcgtcgca
     8101 tataatcatt gagcagacga ccgtcggcag tgcgatgaat atgcggatgc gccacattca
     8161 tccggtatcg ctcgatggcg ccggccaccc ggctgatgaa gacgatggtc ccgtcctgct
     8221 ccacctgttc cacgatgccg acatgggtca ggggatcgtt gaccaggcca tccccgttga
     8281 agtcccaggt attgtcgaag aacaccaggt ctccggcctg taccaccggt ccgcgatgga
     8341 gtcgaccgtt tttccggata tgattgtaaa tgaggcccac gccgttggtc ctgccgtcgg
     8401 ctgagccgtc tgagtagaga tcaatcccgt gggcgagata gatggcgcgt gtcactccgg
     8461 cgcaatcgta actgatgcga cggccctggc tttcgatcgt cgtggcgccg accaggttga
     8521 cggctgtgcg aacgatcgcc tgttgacgag tgtcgctgtg gctggcacgg caacaatcgg
     8581 gaatgggagt gaccgcctgc cgcagtcctt gtgacgacgg agcggcgcaa gcggtgagtg
     8641 cggaggcgag ggccaggcta caccatgcac gtgagagcgt cggcatactc tgtaagtata
     8701 gcgcgtcttc gaactattct cgccaacatc atgccagacc ctcacgggct gctccgcaag
     8761 gcagtccggc acatagtaca tgaacggtaa aagttagcat ctcctgcctt gcccggcgtc
     8821 ttgccaagag cctgatcgcc cggcaggggc tgattcagta ggctgtcacg cgccggcact
     8881 cgagaagact tgtttgatca aggcctgcgc atcctcctga atctggagga gatgggcctg
     8941 tcccttgaaa ctctccgcat agagtttgta cacatcctcc gtcccgctgg ggcgggcggc
     9001 aaaccagccg ttggcggtgg tgactttaag gccgccgatc gaggccttgt ttcccggcgc
     9061 ttctgtcaac atggcgatga tgggttcccc cgcgagttcc ttactccgga cctgctgcgg
     9121 tgagaatttt tgcagtgcgg ccttttgcgc tctcgtggct ggggcatcga tgcgctcgta
     9181 gaccggctcg cccaattggg ccgtcaattc gccatacaac tgcgccggat cttttccggt
     9241 gaccgccagc atctccgcag caagcaggtt catgatgatg ccgtccttat cggtcaccca
     9301 ggtggtgccg tcacgacgaa gaaatgccgc gcctgcactt tcttccccgc cgaatcccaa
     9361 agagccgtcg ctgagccccg gcacgaacca tttaaatccc actggcactt caaccagccg
     9421 gcgttttaat gagcggacca gacggtcgat gatactgctg ctgacgacgg tcttcccgac
     9481 tgcggcacta cttttccacc cggggcgatg cgtgaacaga taggagatcg ccgcggcgag
     9541 gtaatggtta gggttcatca agccggcgcc tggtgtgatg atgccgtggc gatccgtgtc
     9601 ggtgtcgttg ccgaaagcga ggtcgaaccg gttcttgaga gtgatgagcg aggccatggc
     9661 atagggtgag gagcagtcca tacggatctt cccgtcccaa tccagcgtca tgaagcgaaa
     9721 ggtcggatcg accgatgcgt tgacgatctc cagattcaat ccatatcgct ccgccagggg
     9781 acgccagtac gccacggcgg caccacccag cggatcgacg cccaggcgca gattggccgc
     9841 cttgatgcga tcgaggtcaa cgacctgcgc gaggtctgcg atgtaggtcc ccgcgaaatc
     9901 gtagcgcgtg gtagagaccg ctcgaatggc ctgctcgtag ggcatgcgtt tcacgccctg
     9961 aaggttcgcg gccaggagtt cattggcgcg gttctcaatg gctttcgtca cgtcggtgtc
    10021 ggcggggccg ccgtggggcg gattgtattt gaatccgccg tcctcgggtg gattatgcga
    10081 tggcgtgacg atgatgccat cggcgaagcc agaggttcgg tcgcggttgg tctgaatgat
    10141 cgcatgggac atgaccgggg tcggcgtgta gccgtcgtct ttatccaggc gaacctcgac
    10201 accgttcgcg gccagcacct ccagcgcgct gcgctgggcg ggagcggaga gcgcatgggt
    10261 atctttgccg acgaagagag ggccggtcgt gccggctttg atccggtact cacagatcgc
    10321 ctgagtgatc gcgagaatgt gcgcttcatt gaacgttcgt ttcaaggatg agccgcggtg
    10381 accgctggtg ccgaagctga cgcgctgttg aacatcggcc ggatccggcg tctcctggta
    10441 ataggcctgc tcgagtcggg caagattaac gaactgttcc ggttgtgccg gttggccggc
    10501 gcggggatgc tgagccatgg acgcctcaat taggatggat gacgggtgga tgctgagtgc
    10561 cgatccgctt tggctcagta tatacagctc ggtctcgatt gtcaggcgcg ctcggttgcg
    10621 cggtcctcgg cgcgggtgtt aagatccgct cacgttaagg agaggggttt gaccatgccg
    10681 aatatcacct tattgcattc accgacctgc ggagcctgtc cttcggcgaa acgcctgtgg
    10741 aaggaactca gggtaaagta tagctttagc tatcgcgagg tcgatatcac gaccccggac
    10801 ggccaggaat tggcaaatcg acattcagtc cgggcagtgc ccgcgaccat tatcgatggc
    10861 cggttgacgt tcgtcggcgt gccgcctcgc caaagcgccg aaaaggcgct gcagctgaag
    10921 atgaaaccgc agggcgcgtg agatcggaga tatatgaccg ttcctgatga cgatgatttc
    10981 gagctgccga ttcttcccat gatcgacaag gggccgccgc cggagtgcgg cacctgcggc
    11041 gatccgatga agtttatcga cggcgattgg gcctgtgttg attgcaacgg tgaactcctg
    11101 ggtccggaaa ccggttagtg gccggagcgt tcaccggtcg atatcgaatg aatacgatca
    11161 gcgaacaggc aagccgttga ccatgtccca ttcaccgtgg ctcacttccg ttagatgctc
    11221 cgcctcgtaa ccggcccatt ccatcccacg ctcgaaacgc gcctcgttca agatctccgt
    11281 gctctgaaat caaaagaccg gctggcttcg ctggccatca ttgttccttc cgatcagttg
    11341 cgtcgctcac tcaagcgtct cttgatcctg caagagaagc tctccctcct gaatgtgcac
    11401 atcctctcgt ttcaccagct ggctctgcat gtggatcgtg aacggcgcac cgctgaaggc
    11461 gcagccccgg gacggcagat ggatctggtg tcagatgtct ttttcgagca tctcctgcgg
    11521 catatcgggc agcgccggat gccacacacg gagtccctcc gtctctctca gcttccgcac
    11581 ggcgcctggc ctgcactttg ggcgagtctt cgcgatctca aggatgccac cgtggattcg
    11641 gctgtggccg tacgcgcggt agaggaaggg cagtttgccc cggaggaggg ggaaaagctc
    11701 aaaggattat ttaccctcta cgcagccgtt cgagagggga gcgcggcctt aggcgtcggg
    11761 tcaccggacg acttggcttc gctggtcact ccgtttgtgc ctacttcgcc attccttcgc
    11821 ggcctccatg aactctggta ctacgggtcg tacgatctca cgcaaactca gctcacgtta
    11881 ttggaatccc tcgctgcaac tcttccggtc acggtgtatt ttcctgtcga tgctcagccc
    11941 gcctatggat ttgcgcgaca gttccttgaa cggcatctct atccgatggc gggaaccagt
    12001 gacgcatcga tgctggactc accggagcca tctggatctg atgggacaag agccaatgta
    12061 tcggttgaag tccgaaatgc ggctgggatc gacgatgaat tgacgctggt ctgcaagcag
    12121 atcctcacgt tggtcgaaac ccacggatat cgatttgagg agatcggcgt cgtgggacgg
    12181 accctcgtgc cgtatcaatc gacactcgtg cgtcttttcg atcaacatcg cattcccttt
    12241 acgtcgacgg ccgccgttcc gttgttgcga gagccggcga tgaaaacatt gctccatctg
    12301 gccaggctca agggcaacgg tttgcatcgt tcggcgatgc tcgacgtcat cacctcgccg
    12361 tggaatcgcc gcctgacggc tccgcaggga ggcgaaccgc cgcgaccgga cctctggcgg
    12421 ttagccgtcc atgcattggg aattacgaag ggcgaagagg agtggcggcg cctggcgcaa
    12481 ctgggacgtc ttgaggcctg ggctggtacc ggcgatgagt cttccgaaga tccgctcgat
    12541 gccctctcga ttgatgggcc tcaactgcga ttgctctggg actgcgtctc ccccttgata
    12601 gatggagtca cggggctacc ggaatccgga ggatatggcg gcttaaccga tgcgttctgc
    12661 gcgctggccg aggatcatct ttccattccc cttgatatgt ctgattccat cgacgcggct
    12721 acgcagtctc aaggcataac cgatgtcacc gaagcactgg tcggggctct tgcgcaactc
    12781 cgtgagttgg accggctcga tgtccgcatc acgtggcagg aatggacgga cacgttcgag
    12841 ggaattctgg agcggactac ctacgccttg acgtctccgt cccaacaggg tgtgcaggtg
    12901 cttgacgcca tggcggcgag gggccttggc ttccgcgcgc tgttcgtcgt cggcatgaac
    12961 gaaaaaatgt ttccccgtta cattcatgaa gacggatttc tacgtgacag ccatcgtctc
    13021 gtgttgagtg agacactggg ctacaagatc gatcaaaaat tgcagggcta tggggaggaa
    13081 gccttactgt tcgaactgct gcgcgcctcg gcccgtgaac gtctgtacct gtcgtatcaa
    13141 cgggcggatg ccgccggtcg gccattggcc ccctcgggat atttggatgg catgggagtg
    13201 gtgccgcatg ctgcggacgc acagtctctg ttcgctgtgc cgcggcgatg gaaggatcgg
    13261 acggcgttgc ctttattcat tccgccgctc ctgacgcggg aagaacatac ggtgagtagc
    13321 gtcttgcacg gacgcgatgc ggcttccctg ttgaatgcag gggggcgtga gggtgagctg
    13381 tttgctcatg gtctcgctac gcaagccctg atcgaaagcg gcgtgccggc cttgagtgtc
    13441 tacgatggcc tgttgacgga cgccacctcc cattggaacc ggatccgcga acgcgggatt
    13501 tcgccgaccg cgcttgaaac ttatgcgcgt tgcccttttc agtatttctc ggcccaggtg
    13561 ctggacctcg acgcggtacg gcagacggtc tcgatggagc tgtcaccgcc cgctatgggg
    13621 caactgtgcc atgatgcgct gcggctctgt tatctggcgc tgattcgcca agggtggggg
    13681 acggctgcag cgtccgctgc ggttgtcacc gcggaagtca ctcgggccgt cacgcaggcg
    13741 ttcgccgcct atgcgatgac ccacgggacc ggatatgccc ttacctggca gttggcccag
    13801 gacacggttc gacatctggt cgaagcgatg gtcaggttcg attgcgaggc cgccgcagcg
    13861 tcagggttta ttccggtcga gtgcgaaatc gatgcaaagg gtgtcctccc tgatggcaca
    13921 gcaggcgaag ccattcccct gcgtggacga tgggatcggc tagaccgtca tccggtgtcg
    13981 ggggcgctcc gggtgatcga ctacaaatat cgcgcgaatg accggataga cgcgaaggat
    14041 cgccagcttc tgcaggcggc ggtgcgtgcg cagcggttac agcctgcgct gtacacgctg
    14101 atggccgtcg atgggcctgg cgaacagcct cacggccctc agcctgaaca ggtggagttt
    14161 ttgtatctcc tgccacaggg catgccgatg gttgagcgtg catcgtttcc ggcctcttgc
    14221 tggcaaggtc catccggtcc gatgttgagc cgaacggtgc aactcctggt tgatggcatt
    14281 cggagcggga gacatttcat cgtaccggat acggcccact gcgaccattg tgagtttgcg
    14341 accgcctgcc ggaaggctca tcagcccagc ttgtggcgga ctcgccgttc ctccctggcc
    14401 ggtgcattac gcgcgctgcg ctttgagaag gtggcacgtg actgagcaat cgacaatccc
    14461 ggaccaggcg gcgcgggaag cggcggccac caccttcgac cgcaacgtcg tggtgatcgc
    14521 cggagcggga acggggaaga ccaccctgct ggtgaaccgg ctgttgtatc tgctcatgcg
    14581 ccgggccgac ccgctggatc tctcacgcat cgtagccctg acctttacca acaaggcggc
    14641 tacggagatg aagctgcggt tgcgcgagcg gctgcgatcc ttggtgagtc tcgaagggcg
    14701 ggacaatccg gccacaggga gcgggacggt ttcgatcgca gatttacgcc tgcgtttcgg
    14761 ctggacgacg gacgaaattg tggcgcgcgc tgaagcggcg ctgcgcgata tcgaaaaggc
    14821 gcaaatcggg accttgcata gttttgccgc ccacctgctg cgtctctatc ccattgaagc
    14881 cggggtcagt ccgacgtttc aaaccgatga ggatggttct cgcttcgaag agcacttcac
    14941 cgcggaatgg gagctctggt tggaccgtga gttgggtctg tcgggatccg atcatgggcg
    15001 ttggcggctg ctgttggcgg ccttcagttt ggaagatctg cggcaattgg cctatagcct
    15061 gcatagcgat ctgatcgatc tcgatggcct gagggcgcag atcacggaga acggtctcaa
    15121 ccaggtgctg cgcgactggt tcgccgagcg gaaggcgcaa gccgcacgtc tactggcccg
    15181 ctatgacggt ccgaaacggc gcaagatcga gtcgatgctg gccacgattg ttgatctgtt
    15241 cgacctgctg ctcgacgatg gcttggatgg aatccacgcc cttccacctg actctcacga
    15301 gttgctggcc aaagaacttg gaaaggcccc gaacggatgg gtcgaagaag acttcgaaga
    15361 ggccgaatca ctccagcgga tcgccaatcg tttgctcaag gtggatcaag ggctgctcgg
    15421 gcaactgttg gaggtattgg cgccgtttat ccgcgcagtc agaaaatcgt tcctggatac
    15481 tggctggctg agctttgacg gattggtggg caaggcgcgc agtctgctac gggattatcc
    15541 gatgattcgc gagcagctga aacgggacta ccgcgccctc ttggtcgatg aatttcagga
    15601 taccgatccg gtgcaatatg aaatcgtgtt gtacctggcg gagcggttag gtgaacaatc
    15661 tacatcctgg cggacgatcg agctcgaatc gggaaagctg ttcatcgtcg gcgatcctaa
    15721 acaatcgatc tacgcgtttc ggcgggctga cattgaggcc ttcgaccatg tcgtcgagcg
    15781 gctggaacaa ggcggtgccc tgcgttgcga gctcgccacc aatttccgga gccacgcgca
    15841 agtgctcgac ctggttaacg gcgtgttcaa ccgtctcctg gtcgcgcaac cgtcggttca
    15901 gccgccgaac gttccattga ccgcgcagcc gaatcgatcg agtcagttcc gcgataccgg
    15961 cgtggagctt cgactggtgc agtctgagga ggagggtgac ctggattcgg cggctgcgac
    16021 cagggtggaa gccgagcatc tcgcttcgat gatctcccgg tggctgactc cgaccgagcc
    16081 gggaggcgag gcggcggtgg ctggcaccag gctccgcccg ggccacatcg cgctgttgtt
    16141 tcggaagttg acccaggccg aggagtactt ggaagccctt cgacggcatg acattcagta
    16201 catcatcgac ggggagaagc atttctatcg ccggcaggaa gttattgacc tggtgaacat
    16261 cctccgctgc atcgagaatc cccacgaccg tattgcgctg gtcggtgtct tacggtcgcc
    16321 gatcgggggc ttgcctgatt ccgccttggt gagtctccag gaggctcagg catgggatta
    16381 tcgcgaacca ggcccgcttt cgaagtggac gagtccccat gttgagccgc tccgacggtt
    16441 gtatgcggta ctggcgaggt tgcatgaagc agctccccgt tgtccattgc cgcaggtgat
    16501 ggatctggtg tttcagcagc ttcctttgct cgagctggcc gcggcctcga ttcatggaga
    16561 acaggcggtg gccaatctgc tgaagatacg acagatggcc gcggacctgg ctgataggcc
    16621 ggccctcacc ttgaacgggt ttgtggagtt gatgttggag cgactccgtg agcaaccgga
    16681 cgaggcggag agtgcattgt ctgaggatac gctggatgcc gtgcgggtgt tgacgatcca
    16741 taaagcgaaa gggctggagt ttccgttggt gattttggcc gggctacacc atggggatgg
    16801 ggctggtcga gggcccgcgc gacctcagat ttggcacgac tggtccaccg gcacgcaggg
    16861 actcgatttc ggtggcctct gcacggcggg cgcggtgctg gttgcggaga aggcgcggat
    16921 acgcgaacag gcggaacgcc gccggttgtt ttacgtcggg atgacccgtg cacgggagtc
    16981 tctggtgtta tcgggagcct tgccgaaacg ccgggtacgc ggtgccctgc tggatctttt
    17041 ggcgcaggcc gcgggagctg agttcaacgg gatcggggag ggtgggctct cagtgggagg
    17101 cgtcggtttg cgacacacga ttctcaaggg cgaagaccgt tttccttccc gggaacggcc
    17161 gcagccaacg atgttagaag agaccgccgt cgaccaggct ctctgcgatc gctgggtgca
    17221 acgtgatcga gtatgggagg agcatcggtc acagtcgctg atcatctcgc cttcggattt
    17281 cattcgaaag ccggcaccgc tgccgttctc gaatattcag cctcggcaag gccggggttc
    17341 gacttctgga acagccatcg gaacgatcgt gcaccgggtt ctgcaatatt gggatttcac
    17401 cgcggatgcc gaacggcagg tggcggcaat cagcagcgca tcactggcca tcgaggaaca
    17461 ggagtcgaca acccgccagg cgatcgtaga ggacgtgcag gccctgcttc acatctttat
    17521 ccagtcgccc gcatatgccc gcctccgcca ggcgactgtg atcggacggg agatgccgtt
    17581 tctcatcccc tggcaggacg ggcggcaaat tttagagggt gccattgata ttctttaccg
    17641 cattgaaggc aaactctgga ttgccgacta caagacggat atgatcccgc tcgatcaggt
    17701 caccggcagg gcggacctct atcgtgagca agcgcgattg taccgggagg cggtcaccca
    17761 atcgctggga gaaccagtcg ctggattcga attcattttt ctccggctgg gggtgacggt
    17821 tccggtctga acacaaggag taggcatgaa acatcttgga tggatgatca tggtgatcgt
    17881 gacgatcgtc ggctgtgcgg gtccgcggaa agcggaggtg cggccgctcc acgcgccgac
    17941 cggaactccc gaagcggtga gccgacaatt ggagcagggc aaccagttgc tcagcaaaga
    18001 ggattgggct ggcgcgcgag acgcctatct cgcgacgatc caggctgatc aatcactggc
    18061 agaagcgcac tacaatttgg cgctggcctt ggagaaactg ggcgagaaag ccgaagccag
    18121 gaaacattat gtcgctgcag ccaatctggc tcccggcaat aaagtcattt gggacgctcc
    18181 accgctcaga aaatacgaca gcgagctgac cctgggaaag aagtcctgga tggacgccaa
    18241 tccgaaataa acaccttgtg cgacgatgat gctgctcaga gcgtcgcggt tgagctggag
    18301 tctgagcgaa gcggccgctt gcgttgagag gcgatggcaa gaattacggc ccccgcaacg
    18361 atcatgggaa tgctgagcat ctgccccatg gaaatcgtcc cgacaatgaa gccgatctgc
    18421 gcatccggct cccgaaaaaa ctccaccaca atccgacaaa gcccgtagcc gaccaggaaa
    18481 gatccgaaga cggttcctga tggcggcaga cggcgggtga tcaaccacag caccgtaaac
    18541 agcaacaggc cctccaggaa cgcttcataa agctgtgagg gatggcggca gaccatcccg
    18601 ccggctggaa ataccataca ccagtccaca tcagtggggc ggccgtacag ctcaccgttg
    18661 ataaagttgc caattcgccc cagtccgagg ccgaccgggg tcacaccggc ggccaggtcg
    18721 gcaatcgtga gcaccgtcat gccttgccgt tttgcaaaca ggatcagcgc cacgatggta
    18781 ccgatcagcc caccgtggaa ggacatgccg ccttcccaga ccgcgaaaat cttcagtgga
    18841 ttctccaggt aataggacag gttgtagaac agcacatagc ccagccgtcc gccggcaaac
    18901 acgcccaccg ccgcatagac gatcatgtcg tagacctgat ccttgttcag cggcagtttc
    18961 tgagccctcg ctcgcgcttc gatgatgaag taggcgagcg tgagtccgat gagatacatc
    19021 aggccgtacc atcggaactg caatgggccc aatcgaagaa atacggggtc gatatccgga
    19081 tagggaatgg cgtgtaacca gggcagcata gaaggactcc acatagtttc gcgatcttat
    19141 gtgagcgtgc tcgacattgc aaggcaagcg gcgagcccgc gccaggcaag gcgtgagcgg
    19201 cactcatgaa agttccctac gcacacctgt cgcttttctg aaacggttgt ctcctgctgt
    19261 tgttcacaaa acagcaccct ttatgaggcg tctctaacgt gcagctcgcg aatcacacaa
    19321 atcaggccga accgcacata cgcatcgtct ggcacgcttg atgctgtata gcgagatagc
    19381 tactcgccaa gtcagtgaac catcaacctt gttgtacgag agggaggaag tcacgatgtc
    19441 taccaagggg cgtgaagcag ccaagattgc ag
//
LOCUS       DAOQPD010000075        19415 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1405_length_19415_cov_25.990548, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000075 DAOQPD010000000
VERSION     DAOQPD010000075.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 19415)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 19415)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19415
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1405_length_19415_cov_25.990548"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1040)
                     /locus_tag="PK063_14795"
     CDS             complement(<1..1040)
                     /locus_tag="PK063_14795"
                     /inference="COORDINATES: protein motif:HMM:NF016241.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF481 domain-containing protein"
                     /protein_id="HMZ98368.1"
                     /translation="MMRRYACFFLALLIVALTAYGVNAESPTPTDTTAAAPTLDSVTL
                     KDGTVIYGRVLGMIADELHIKTGFGPTAGDDIVKIMWPNVAKLVVNRPIPFTLKEGTT
                     VVGTAQPGEPGTLTLQAAPMGTPMAIPLDAVVGMNQPAVIYTGALQAGFSQTTGNSHL
                     RNGSLLGELSARSESLRLTILGRYIYGDNSGNLIVRNSRGTIKLDFFLTKRLYWFASA
                     YFEQDTFQDLKLRTALATGPGYQLLDRGDLTGFFKDMTLWAEAGAAYFNEDFKLADDK
                     SSTRGRWAVKWNWPLWGGDQVSLYHFQEGFQSLANSKDLYLTADTGLRFKVWGGLVSG
                     FQWTMRYNKNPPP"
     gene            complement(1427..1738)
                     /locus_tag="PK063_14800"
     CDS             complement(1427..1738)
                     /locus_tag="PK063_14800"
                     /inference="COORDINATES: protein motif:HMM:NF012422.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HMZ98369.1"
                     /translation="MDKVFPFSTNRPDQPTPREQEILNYIWAGLTSQEIAARLQIAQK
                     TVESHRANLLRKFRATNAAQLLRLALLEGLLSVPSTERAPDVKRVVQSAKASRRLTSI
                     K"
     gene            complement(2001..3791)
                     /locus_tag="PK063_14805"
     CDS             complement(2001..3791)
                     /locus_tag="PK063_14805"
                     /inference="COORDINATES: protein motif:HMM:NF025885.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ98370.1"
                     /translation="MAPDPSLRTPDFLCSLFERLEYVVLEHVAGTQFRILGHPSPWLF
                     RLYPEAEASLQLSVDSRTPVLHNFLADAAEVWQTGDAHIGRSGFWTEQTAFDVPWHFE
                     ALALREGTSRLLVIQHSTAAYEQQAAMLQRAREQALQQHEQERGHQRTQQDLTMQLVD
                     MERARDDVAAILQDLGLATLLIDQEGHVRFVSASAASLLERPSASIKPDLRWETLLPV
                     TKADRLTVQSLLEHPIPQRERVCCHIDTPAGRRLWLDLELHDDPRDRRSKIVFLHDMT
                     DVYHLRRMLELKAHYHDLIGKSRGMTQIYEQLQDLARVDSTVLIEGETGTGKELVARA
                     LHQASARRTGPFIAANCAGLTDSLLGSQLFGHKKGAFTGAIDDQQGLFEAAQGGVLFL
                     DEIGDIPHTVQTNLLRVLQEKEVTRLGETKPRKINVRVLTATHHNLSQDVAKGTFRAD
                     LLYRIRVARIHLPPLRERKEDIPLLVTSFLAEGRASMGKLIHRASPATMAALMDYQWP
                     GNVRELKSTIECAMIHCKGDSLEATDLPPELQREPTALTPEPITTDERSRFVSALGQA
                     RGNRTKAARLLGMSRATFYRRMTELDLPAN"
     gene            complement(3781..4317)
                     /locus_tag="PK063_14810"
     CDS             complement(3781..4317)
                     /locus_tag="PK063_14810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rab family GTPase"
                     /protein_id="HMZ98371.1"
                     /translation="MIEKKICMLGAFAVGKTSLVRRFVSSCFSDQYQTTIGVTVDKKS
                     MTVDGTSLTMVLWDLYGEDEFQKLRSSYLRGSSGYLLVLDGMRRATLDIALHVQERAS
                     DTLGPVPFVVLINKHDRRAEWDITDQDLAQLAQRGWSVVMSSAKTGQGVEEAFTTLAR
                     AMLTPSNSSAAAGRPHGS"
     gene            complement(4328..6058)
                     /locus_tag="PK063_14815"
     CDS             complement(4328..6058)
                     /locus_tag="PK063_14815"
                     /inference="COORDINATES: protein motif:HMM:NF012894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HMZ98372.1"
                     /translation="MAQPPNRSTPPAEHDYAELRSLLLAPEQTRLEQLQEQVEHIDLN
                     AQNLSRVLPDAIALRGEGDHQLTHVLTPHVSEALGASVRRQPHMIVDAIAPIMMPAIR
                     QAIANALRGMVQSLNQTIEHSLSIQSVKWRVEALRTGKPFAEIVLLHTLRYRVEQVFL
                     IHSQTGLLLAHAAGDAVAVQDQTLVSGMLSAIRSFVQDSFGADPEQVLNTLQVGELTV
                     WIEQGPAAILAAVIRGTPPESLRLHLQDTLTRIHAERADALARFTGDAATFASVTPLL
                     EECLRAQFESRRRGIAPMTWVLIIGALLVTTWWALSTYQERQRWQSYLSRLATEPGLV
                     VTDAEPEGGRYRLTGLRDPLAADPAILMQDSGIDTSRVVAKWQPYYALDTSFILKRAG
                     FALSPPPTVHLALEGSHLTAGGTASADWIRQSRSVARAIPGLDGYDDRRLVSQSLDML
                     RQQFTETSILFEQGSSKLVSPEQLQQVRRIVGMLRQLEDLARLASAAVTVSIVGQTDV
                     VGGTSQNRRLSDGRAKAVLDAIHPASFPALTFHTRGMAQEAELQRSTPAVAHPQHRRA
                     SLEITIQPMP"
     gene            complement(6175..6789)
                     /locus_tag="PK063_14820"
     CDS             complement(6175..6789)
                     /locus_tag="PK063_14820"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98373.1"
                     /translation="MSRQTDLDRTRRSERTPTTLAETETETALADDPTAGNNLDKIRD
                     ILFGAQVRDHERRFTKLETQLLAEAAQLRNDLKDRFASLEQYIRTEVEQVTGRLNAEE
                     QGRTKAVSALTAELHTLAGVLQQTATQLREQSEQADRDLRDQLQHQAASLTGEFTQQH
                     ATLSATLDQAVQQLSHQKTDRTSLATLFQELSQRLSHDQPPQQA"
     gene            complement(6928..7728)
                     /locus_tag="PK063_14825"
     CDS             complement(6928..7728)
                     /locus_tag="PK063_14825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HMZ98374.1"
                     /translation="MSLANLITQYVVQYGFRIMGAILVIVAALFVANSVGRLFERWLN
                     EQDLEPPLRLLLLRLLKALLVILGVLIALDQLGVQIAPLVAGLGVAGLGVGLALQGVL
                     SNVVAGLSIIFTKPYRVGEHISLLGVHGDVAKIDIFTTTLLHPDHSRIVIPNRKVVGE
                     ILHNFGTIRQLDLSIGVSYQTDIETTLRVLRELVSRHPKVLQDPVPMIGIAAFADSSI
                     TLSIRPWVPVASVGSAHIELNQAIIQRLRADGVDIPFPQREVRLLNPS"
     gene            complement(7746..9854)
                     /locus_tag="PK063_14830"
     CDS             complement(7746..9854)
                     /locus_tag="PK063_14830"
                     /inference="COORDINATES: protein motif:HMM:NF024893.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HMZ98375.1"
                     /translation="MKILVGIGVVILLLLILIIALPFLIDLNKYQDRYRPLIEEALNR
                     KVELQDIRLTIWPRIGARIGGFVVQDDPAFRTGPFASLASLDVGVKLLPLLKGRVDVE
                     EITLRDPVILVLKNSQGQLNISTIGAKPTSPAAPSKPEAPGQPAGSPLQALALFAVDR
                     VSIDGGKLTYRDESTAKPTEYTVTQLEFLLTSVHLGDSPTVHLGATVLPYNLPVHLDG
                     TFGPLVETLDVKSFSFNLGLGKVAVGLKGRAVGGNLDATINALQIDTADLPIALPLTK
                     PVQIKDLHLTLHALYPIPPDTPPASQVDLTDLGLTLVMGGSAINIKGTATKGLANITA
                     ASASINSSDLPVAVPLAKPVEVKDLHMNVRAKYPPKEGTAPLELAEVPNLGLTIALGS
                     SRVEVKGSVLGGLAKVTATSKLVNSADLPVALPLKKPVEIKDLQAAAEMKGQEARLTN
                     LTLQVFGGFLRTQGTLGLGTPTPPFTGTVALQGLQVGPALQAVGTDQVSLSGTANAEL
                     ALSGRGFTHPDLVKALAGTGRMSVREGKIEGINLLQQAAMLLKVVGVSLDNVKATAFS
                     TIESDVVIKQGLIGLQRVLIDSHDFQATGGGTIGLDQSLDMKLNLNLSQALSQKIAAG
                     SPIAKVAMTNGRLSLPLVITGSTQAPSYGLDTKMFAGKVQEQVKEKVKGAVGDLLKGS
                     AKPEDLKKQGKDLLKGLFGR"
     gene            10081..10170
                     /locus_tag="PK063_14835"
     tRNA            10081..10170
                     /locus_tag="PK063_14835"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10115..10117,aa:Ser,seq:gga)
     gene            10464..10563
                     /gene="ffs"
                     /locus_tag="PK063_14840"
     ncRNA           10464..10563
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="PK063_14840"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            10665..12545
                     /gene="dnaX"
                     /locus_tag="PK063_14845"
     CDS             10665..12545
                     /gene="dnaX"
                     /locus_tag="PK063_14845"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: protein motif:HMM:NF004046.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HMZ98376.1"
                     /translation="MDYQVSARKYRPGTFDDVIGQSHVVQTLMNSIATKRIAHAFLFS
                     GTRGVGKTTVARILAKALNCEQGPTGSPCNTCANCQEITQGTSVDVVEIDGASNTSVD
                     DVREIRENVKFTPFRGQYRVYIIDEVHMLSNSAFNALLKTLEEPPSHVVFIFATTEIH
                     KIPATILSRCQHYNFRRISKAEIVQRLRHVADQDGLTIEDRSLMALARASEGSMRDGL
                     SLLDQVIAFGGKTIRHHDLETLLGAVPQERVRAMVEAVIDQNSAKALQVIAGLLDQGH
                     DVRAYCADLVEYVRNMLVAAVVPAGPELRGLIEVTDEDLTQLARDAEQFSVEHLQELF
                     RLWAAAEDHLRVSAHPRFVLETAAVRATRLLRAPESPAGLPGVNVQSSATPVDRATGT
                     RTSMSSSEKVVSPKPTKRDTVKSSSDAGDKPVVPSASAPAPAPVARPREAVVPSSQTP
                     APSIPSAQASATAQVPVESASPKPEPPSHRATASPSAEINWEEFQEAVSGQHPNIAPF
                     LEMGRVVKIEGGLVTLGFTKQATVARAMLEKEDNLQSLAALGERIYGTALRVRIIEVA
                     EQDPEATPTMKQLRVAKEQEQRVILTQQAKAHPLVKQALEMFGGELAEVRTTTPAQEV
                     QE"
     gene            12542..12865
                     /locus_tag="PK063_14850"
     CDS             12542..12865
                     /locus_tag="PK063_14850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010330208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HMZ98377.1"
                     /translation="MKSPFGNMSNILKQAQAMQEQMAKVQEQAATKTVSGTAGGGIVT
                     VTVNGAMDLLSVKIDPEVVKSGDVDMLQDLVVAAGNDALKKSRDMMAEEMKAVTGGMK
                     IPGLF"
     gene            12944..13546
                     /gene="recR"
                     /locus_tag="PK063_14855"
     CDS             12944..13546
                     /gene="recR"
                     /locus_tag="PK063_14855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HMZ98378.1"
                     /translation="MSIDQQGLLAKLVRELVRLPGIGQKSAQRLAFHLLKAEREDALR
                     LAEAIQAVKDGLSFCRQCRNIAEGELCEFCRDSKRDRSKILVVEEPSTLYAIERAGGY
                     RGLYHVLLGVLSPLDGVGPSDIRAEELLERVKAGGVEEVIVATNPTIEGEATAIYLTR
                     LLKPHHVRVTRIAYGIPVGMDIEYADEVTLVKSIEGRRDL"
     gene            13707..14114
                     /locus_tag="PK063_14860"
     CDS             13707..14114
                     /locus_tag="PK063_14860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014448456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HMZ98379.1"
                     /translation="MKTSAKKSTPTRKKPAKANGVKYPDIQKDLEGQRAAILAEAGVV
                     LTNPTGLEVFPDVSDQASAEADQHFSFRIRERERKLLKKIDEALGRLATHTYGICEGC
                     QGDIPYKRLKARPVTTLCIECKTSQEEAEKSPR"
     gene            complement(14181..15326)
                     /locus_tag="PK063_14865"
     CDS             complement(14181..15326)
                     /locus_tag="PK063_14865"
                     /inference="COORDINATES: protein motif:HMM:NF024579.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98380.1"
                     /translation="MHRRLSLLPALLTMFALLTGCETPPPARAPLPPSESDLDLLKST
                     KLCDTRKVFQEHHPGIVPKTQAWGSGQELRFSAEQSLSKGEESYFFDEDGTLVGTLFI
                     FRSGLDLGPYKTLRYTLTQLKPSLEFYLTVAQLADRQNMASSTLYDTGDEKTTTRYLV
                     LGDRKNPQLLAASFSIDPYVKLFSPYRKEFLDRLRDTGQQSGGQHLDTQGAEDKEPFA
                     SLQQFARGQTAQLAYCGAKNQTIALDAYQKASASGFTSQVWQAELHHRLGVSWEAAGD
                     LEKAKRELLASLAQRPNSPEVVNNLGYVYGKLGEKQNALASFEKAVLMRPNYAIARFN
                     LAEAIAEANPRRAINEYETYLALTEGIPEEADRSALAQSRVKALKHQ"
     gene            complement(15477..15806)
                     /locus_tag="PK063_14870"
     CDS             complement(15477..15806)
                     /locus_tag="PK063_14870"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98381.1"
                     /translation="MRGTLATIMLGLLLTTGCSTTNQVATQDQNYNAPLSIYSAMDST
                     SLVYSDPMAASQANDNPYRWLGFVLHPVGHLVDYTVNRPLYAIARHAPYLFGYTAEDS
                     MIDSQRR"
     gene            complement(16367..16441)
                     /locus_tag="PK063_14875"
     tRNA            complement(16367..16441)
                     /locus_tag="PK063_14875"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16407..16409),aa:Val,seq:cac)
     gene            16627..17943
                     /gene="trmFO"
                     /locus_tag="PK063_14880"
     CDS             16627..17943
                     /gene="trmFO"
                     /locus_tag="PK063_14880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HMZ98382.1"
                     /translation="MREDIVIIGGGLAGSEAAWQAAHRGAKVTLYEMRPKETTKAHKT
                     GDLAELVCSNSLGSMDPLNAPGILKGEMRRLNSLVIRAAEEARVPAGSALAVDREIFA
                     RAITQALEGHPNIRIIREEVTEIPADAVAIIATGPLTSEKLSKAISELTHERHLYFFD
                     AISPIIDADSINMDIVYRASRYGKGGADYLNCPMDEAAYNALYDAMMAAEKVQPKEFE
                     KVAYFESCIPIEVMAERGRQTMQFGPLKPVGLDDPKTGRRPYAVVQLRTENVHGTCYN
                     MVGFQTKLTYPEQKRVFRLIPGLEQAEFLRFGSLHRNTFINSPQLLRDTLQLKTRGTV
                     FFAGQLVGVEGYTESAAMGGIAGINAARGLAGQPLVTPPPTSAHGCLMAHITKSDPAH
                     FQPMNTNFGLFPPVTVKTRDKDQKRRLIQQRAVEDFDAWIAQSGLS"
     gene            17916..18878
                     /locus_tag="PK063_14885"
     CDS             17916..18878
                     /locus_tag="PK063_14885"
                     /inference="COORDINATES: protein motif:HMM:NF001399.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009037 - tyrosine-based site-specific
                     recombinase activity [Evidence IEA];
                     GO_process: GO:0006313 - transposition, DNA-mediated
                     [Evidence IEA];
                     GO_process: GO:0007049 - cell cycle [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HMZ98383.1"
                     /translation="MDRAIRAFLDVLAVQDDASPQTIRAYTSDLAQFRAFALAALKPR
                     DTLTVESIEAGLIREFLASRDRKGEKKTSLARKLACLRSFFRYLVRVGRVQANPAEDV
                     RAPKLPKHLPQVLTKDDAGALMEFPPGDAREGLRDRAILETLYSTGARVSELVGMDRQ
                     DISRSEGVVRVRGKGGKERVIPLSPLALEAIDAYHAQASVTAASNSSDRGAPGGSPVF
                     RNRRGGRLTTRTIARIVAKYSGQLSGGAIHPHTLRHSFATHLLDEGADLRAIQEMLGH
                     VSLSTTQKYTHLATDQLLALYDRTHPRAGAAGEAEQGNKQKGSR"
     gene            18875..19411
                     /gene="hslV"
                     /locus_tag="PK063_14890"
     CDS             18875..19411
                     /gene="hslV"
                     /locus_tag="PK063_14890"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0051603 - proteolysis involved in protein
                     catabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease subunit HslV"
                     /protein_id="HMZ98384.1"
                     /translation="MKIRSTTVLCVRRGNQVTMGCDGQVTVGTTVMKHNARKMRRMHN
                     DTVLSGFAGATADAFTLFEKFEAKLAEYRGNLTRAAVELAKDWRTDRVLRRLEALLAV
                     ADLDHSFIISGTGDVVEPEDGILAIGSGGPYALASARALLAHSELGAEPIVKESLMIA
                     GGIDIYTNQQIVIESLTR"
BASE COUNT         3919 a         5371 c         6024 g         4101 t
ORIGIN      
        1 ggcggcggat tcttgttgta ccgcatggtc cattggaatc cgctgaccag cccgccccac
       61 actttgaatc gcaacccggt atcagccgtg agatagagat ctttggaatt ggccagcgat
      121 tggaaaccct cctggaagtg gtacaggctg acctgatcgc cgccccacag cggccaattc
      181 catttgacgg cccatcggcc acgggtgctg gacttgtcgt cggcgagctt gaaatcttca
      241 ttgaagtacg cggcgccggc ttctgcccag agcgtcatgt ctttgaagaa acctgtcagg
      301 tcaccgcgat cgaggagttg atagccggga ccggtcgcga gcgcggtgcg cagtttcaag
      361 tcctgaaagg tgtcctgctc gaaataggcg gacgcgaacc aatacaaccg cttcgtcaga
      421 aagaagtcaa gcttgatggt gccgcggctg ttccgcacga tgaggttccc gctattgtct
      481 ccgtagatgt aacggccgag gatcgtcagc cgcagtgatt cgctgcgggc agacaactcg
      541 ccgagcaggc tgccgtttcg caaatggctg ttgccggtgg tttgggaaaa cccggcttga
      601 agcgcgcccg tataaatcac ggcaggctga ttcatgccta caaccgcatc cagcggaatc
      661 gccattggcg ttcccatcgg cgcggcttgc aaggtgagcg tgcccggttc gccgggctgt
      721 gccgtgccga ccaccgtggt gccctctttg agggtgaacg gaatggggcg gttcacgacc
      781 agtttggcca cgttcggcca catgatcttc acgatgtcgt ctccggcggt cgggccaaat
      841 ccagtcttaa tgtgcaactc atcggcgatc atgccgagaa cacgtccata gatgacggtg
      901 ccgtctttga gcgtgaccga gtccagtgtc ggcgctgcgg cagtggtatc cgtgggcgtc
      961 ggtgattcgg cattcacgcc gtacgccgta agcgctacga tgagcagcgc aagaaagaaa
     1021 catgcatagc gtcgcatcat tccatcctcc tggggcttgc gaatggcaac ggtgtgctgg
     1081 ttgcctgatg agtgaaagac attttgcgtt gtataattga ttctgcgtag gagatcaact
     1141 tttctcccgc ccattcttcc gcatggccct ggctcccgcc gagtcgcata gatgagatct
     1201 gccgcctccc gcgctcacgg actgtccccg gcaatctgcc gccatcatga tgtttccgcc
     1261 gaccagacgg tccaggaccc gttgcgaaga agcgtccgca cagattatcg cggagccgca
     1321 cagtacacat gtgtcaagat gagacggcat tgggtgatcg tgacacgccg gcgcatggac
     1381 gaataggctg tatgccgacg tgagcgtaga gacaaagcgg gactcttcat ttgatgctgg
     1441 tgagtcttcg cgaggccttc gcgctctgca ccactcgttt cacatccggt gcgcgctctg
     1501 ttgacgggac ggagagcagc ccttccaaca acgccaggcg gagcagttgc gcggcgttcg
     1561 tagcccggaa ctttctcagc aagttggcgc gatgagactc cacggtcttc tgtgcgatct
     1621 gcagtcgggc cgcaatttcc tggctggtta atccggccca aatgtaattc agtatctctt
     1681 gctcgcgcgg cgtcggttgg tccggccggt tggttgaaaa cggaaatacc ttatccatcg
     1741 ttgcttctca tgcccctttc tgatcgtcct gcccggtgat ctcacggaat tgcacgcagt
     1801 ggtttgtccg gtggttttta caagctccgt gcctgaactt gcggaatgtg cgtcaggatg
     1861 agccattgcg ctggatcagc atgcagccgg cgcgatgcga gggaccgtgg cgataggatg
     1921 agacacatca catcgtcttt cattgtctcg ctggagacga tgtgagacag cgtccgcgga
     1981 aggtcggaca gtctaggcgg ctagttggcc ggcaggtcga gttcagtcat tcggcggtag
     2041 aaggtggcgc ggctcatgcc gagaaggcgt gcggctttgg tgcggtttcc acgggcctgt
     2101 ccaagggcgg aaacgaagcg gctgcgttcg tcagtcgtga tgggttcagg cgtaagcgct
     2161 gtcggctccc gctgcagctc cggcggaaga tccgtcgctt cgagtgagtc acctttgcag
     2221 tgaatcatcg cgcattcgat cgtgctcttg agttctcgca cgttgccggg ccactggtag
     2281 tccatcaacg cggccatggt cgccgggctt gcccggtgga tgagttttcc catgctggct
     2341 cgcccttcag cgaggaaaga ggtcaccagc agcgggatat cttcctttcg ctccctcagc
     2401 gggggaaggt gaatgcgagc gacccgaatg cggtagagaa gatcggcgcg aaaggttccc
     2461 ttggccacgt cctggctgag attgtggtgc gtcgccgtca ggacgcgcac gttaattttt
     2521 ctcggcttgg tctcgccaag ccgggtcact tccttttcct gcagcactcg cagcagattg
     2581 gtctgcaccg tgtggggaat gtcgccgatc tcatcgagaa acagcactcc cccctgtgcg
     2641 gcttcgaaga gcccctgctg gtcatcgatc gcgccggtaa aggccccttt tttgtgaccg
     2701 aagagctggc tgccgagcaa ggaatccgtc agccccgcgc aattagccgc gataaagggg
     2761 cccgtgcgtc gggcactggc ttggtgcaag gcgcgggcga ccagttcttt tcccgtcccg
     2821 gtctcacctt cgatcagaac ggtcgaatcc acgcgcgcca ggtcttggag ctgttcatag
     2881 atctgggtca tgccgcgact cttgccgatc aaatcgtgat agtgcgcttt gagttccagc
     2941 atacgccgaa ggtgatagac gtccgtcatg tcatggagaa agacgatctt gctccgtctg
     3001 tcccgcggat cgtcgtgcag ctctaggtcg agccacaggc gcctccctgc cggcgtgtcg
     3061 atgtggcagc aaacccgttc ccgttgcggg atcggatgct caagaagcga ctgcaccgtc
     3121 agtcgatcgg cctttgtgac tggaaggagg gtctcccacc gtagatcagg cttgatgctg
     3181 gctgagggcc gctccaacag actggcggca gatgcactca caaagcgcac atgtccttcc
     3241 tgatcgatga gcagggtggc cagccccagg tcctggagga tagccgcgac atcgtcccgc
     3301 gcccgttcca tgtccaccag ttgcatggtc agatcctgtt gcgtgcgttg gtgtccgcgc
     3361 tcctgctcat gctgttgaag tgcctgctcg cgcgcccgct ggagcatagc ggcctgttgt
     3421 tcataggccg cagtgctgtg ctgtatgacc aacagacggc tggttccttc gcggagggcc
     3481 aatgcttcaa agtgccaggg gacgtcgaag gcggtctgtt cagtccagaa gccagagcgg
     3541 ccgatgtgcg cgtcgccggt ctgccacacc tctgccgcgt cagccagaaa attatgcagc
     3601 acgggggtgc gactgtcgac ggagagctga agactcgctt cagcctccgg atagagacga
     3661 aacagccagg gtgatggatg gccgaggatg cggaattgcg tgccggcaac atgttcgagg
     3721 acgacgtact ccaatcgctc gaataacgag cacaggaagt ccggcgtgcg gagtgacgga
     3781 tcaggagcca tggggcctcc cggctgctgc cgaagagttc gatggtgtga gcatggcgcg
     3841 agcgagtgtg gtgaatgctt cttccacgcc ttgcccggtt ttggcgctgc tcatcacgac
     3901 tgaccatcct cgttgcgcca actgggcaag gtcttgatca gtgatatccc actccgctct
     3961 ccggtcgtgc ttattgatca ggacgacgaa cggtacgggg ccgagtgtat cggatgcccg
     4021 ttcctggacg tgcaaggcaa tgtccagcgt cgcccgccgc atgccgtcaa ggacaaggag
     4081 ataccctgag gacccccgca gataggacga gcgtagcttt tgaaattcat cttctccgta
     4141 aagatcccac aggaccatgg tgagagatgt cccgtcgacc gtcatcgatt ttttgtcgac
     4201 tgtgacgccg atggttgtct ggtactggtc ggaaaagcag ctgctgacaa aacgccgaac
     4261 cagactggtt ttccccacgg caaacgcgcc caacatacag atctttttct caatcatgcg
     4321 gagagtctca cggcatcggc tgaatggtga tttccagtga ggctcgccga tgctgcggat
     4381 gggcgacggc tggggtcgac cgctgcaatt cagcctcttg ggccatgccc cttgtgtgaa
     4441 acgtgagtgc gggaaaggat gcggggtgga tcgcatcgag gacagctttg gcgcgaccgt
     4501 cactgaggcg tcgattctgg ctcgtcccgc ctacgacatc ggtttgtccg acgatggaca
     4561 ccgtcacggc ggcgctggca aggcgggcca ggtcctccag ctgccgaagc atcccgacga
     4621 tgcggcggac ttgttgaagt tgttccggcg atacgagctt gctgctcccc tgttcaaata
     4681 aaattgacgt ctcggtgaat tgctgacgca acatgtcgag agactgactc acgaggcgtc
     4741 gatcgtcata gccatcgagg ccgggtatcg cgcgagcgac tgagcggctt tgcctgatcc
     4801 aatccgccga agccgtgcct ccggcagtca gatggcttcc ttccagggcc aagtgaaccg
     4861 tcggtggtgg tgagagtgcg aatcccgcgc gtttcagaat gaacgacgtg tcgagggcgt
     4921 agtacggttg ccacttcgcc accactcgac tggtgtcgat gccgctgtct tgcatgagga
     4981 tagccgggtc cgccgcgagg gggtcacgaa ggccggtgag ccgatagcga ccgccttccg
     5041 gctcagcgtc ggtgacgaca agtccaggct ccgtggccag gcgagacagg tagctctgcc
     5101 agcgttggcg ctcctggtag gttgacaggg cccaccaggt cgtgacgagg agcgcgccaa
     5161 tgatcaacac ccatgtcatc ggtgcgatgc cgcgccggcg tgattcgaac tgggcgcgca
     5221 aacactcttc caatagtggt gtgacactgg cgaacgtggc ggcatctccg gtgaaccggg
     5281 ccaaggcatc cgcccgttcg gcgtgaatac gggtgagcgt gtcttgaaga tggaggcgaa
     5341 ggctttccgg tggagtgccg cgaatcaccg cggcgaggat ggccgccggc ccctgttcga
     5401 tccagacggt gagctcaccg acctgcaacg tattcagcac ctgttccggg tcggcgccga
     5461 atgaatcctg cacgaagctc cggatggccg acagcatacc ggacaccagg gtctggtcct
     5521 gcacggccac tgcgtcgccg gcggcatgcg ccagcagcag tccggtctgt gagtgaatga
     5581 gaaacacctg ttcaacccga tagcgcaagg tatgcagaag aacgatttct gcgaacggct
     5641 tgccggtgcg cagcgcttcc actctccatt tcacactttg gatcgacagg ctatgttcga
     5701 tggtttgatt gagcgattgg accatgccgc gtaaggcatt ggcgatggcc tggcgaatgg
     5761 ccggcatcat gatcggagcg atggcatcca cgatcatatg aggctgtctc cgcacggacg
     5821 cgcccaacgc ttccgatacg tgcggagtta agacgtgtgt gagctggtgg tcaccctctc
     5881 cgcgtagcgc gatcgcatcc ggcagcacgc ggctgaggtt ctgcgcattg aggtcgatat
     5941 gctcgacctg ttcctggagc tgctccaaac gcgtctgttc cggcgccagc agaaggctgc
     6001 gtagttcagc atagtcgtgt tctgcagggg gagtgctgcg gttaggtggc tgtgccatac
     6061 cggttcctct gtcgagcgcg atgagggagg ggcacagtgg agtacatgtg acgatgaacg
     6121 ctgcggctct gtgtgaggag ggcaggccgg gaccacgcag gcatgaaacc tggattatgc
     6181 ctgttgtgga ggctgatcat gcgagagcct ctgcgagagt tcctggaaca aggtcgccag
     6241 cgatgtccgg tcggtcttct gatgggaaag ttgttgcacg gcctgatcga gtgtcgccga
     6301 cagggtcgca tgttgttgcg tgaactcacc cgtcagtgag gcggcctgat gctgcagctg
     6361 gtctcgcaga tcgcggtctg cctgttcgct ctgttctctc aactgcgtgg ccgtttgctg
     6421 gagaaccccg gcgagggtgt gaagctctgc ggtcagcgca ctgaccgcct ttgtgcgacc
     6481 ctgctcctcc gcgttcagcc gccccgtcac ttgttccacc tctgtacgga tgtattgttc
     6541 cagcgacgcg aaacggtctt tgagatcatt acgtagttgg gcggcctctg cgagcaattg
     6601 cgtttcgagc ttggtaaatc ggcgctcgtg atcgcgcacc tgggccccga agaggatgtc
     6661 gcggatcttg tcgagattat taccggcggt gggatcgtcg gcgagggcgg tttccgtctc
     6721 cgtctcggcg agcgtggtgg gggtgcgttc cgaacgtcgg gtgcgatcga gatctgtttg
     6781 cctgctcatg gtgtcgtctc cagggtcgca gtcgtccgtc aaggaaaggg ggggtacact
     6841 agcatattta cgcaggtgca acaagccacg cggggggcat caccagtgga ccagataggg
     6901 ccgatgatag ggtcgtgtgc tgttcgatta ggaagggttc agcaggcgca cttcacgttg
     6961 cggaaaggga atatccacgc catctgcgcg caatcgctgg atgatggcct ggttgagttc
     7021 gatatgtgct gaaccgacgg aagcgacagg gacccagggc cgaatggaca gggtaataga
     7081 ggagtcggcg aaggcggcaa tcccgatcat cgggacagga tcttgaagga cttttggatg
     7141 tctggagacg agctcgcgca acacgcggag tgtggtctcg atatcggttt gataggacac
     7201 tccaatggag aggtccaact gccggatggt tccgaagttg tgcagaattt ctccgacgac
     7261 tttgcggttc ggaatgacga ttctggaatg gtcgggatgc agcagagtgg tcgtgaagat
     7321 atcgatcttc gcgacatctc catggacccc caagagggag atatgttcgc cgacccggta
     7381 gggctttgtg aagataatcg aaagccccgc taccacattg ctcagtaccc cttgcaaagc
     7441 cagtccgaca ccgagaccgg cgacgccgag gcccgccacc agcggcgcga tttgcacgcc
     7501 gagttgatcc agcgcaatga gaaccccgag gataaccagc agggctttca ggagtcgcag
     7561 gagcagcagg cggaggggcg gctcgaggtc ctgttcgttc agccagcgct cgaagagacg
     7621 gcccaccgaa ttggccacga aaagggcggc gacaatgacg agaatcgccc ccatgatgcg
     7681 aaatccgtac tgcaccacgt attgagtaat caaattggcg agtgacatgt ttcctccgcc
     7741 ccctcctacc gcccgaacaa tcccttgaga agatctttgc cttgcttctt gaggtcctcc
     7801 ggcttggccg accccttcag gagatctccc accgcgccct tgaccttttc tttcacctgc
     7861 tcctggactt tccctgcgaa catttttgtg tcgagtccat acgaaggggc ttgagtgctg
     7921 ccggtaatta ccagtggaag cgagaggcgt ccattggtca tggcgacctt ggcaatggga
     7981 gagccggcgg cgattttctg gctcagggcc tgagacagat tcagattcag tttcatgtcg
     8041 agtgattggt cgaggccgat cgtgccgccg ccggtcgcct ggaaatcatg gctgtcgatc
     8101 aagacgcgct gtaggccgat cagtccttgt ttgatcacca cgtcgctttc gatggtggag
     8161 aacgccgtgg ctttgacatt gtccaacgag acgccgacca ctttgagcaa catcgcggcc
     8221 tgttgcaata aattgatccc ctcgattttg ccctctctga cggacatgcg gccggttccc
     8281 gccagggctt tcacgagatc cggatgagta aagccacgcc cgctgagcgc cagttcggcg
     8341 ttggcggtgc cgctgagcga gacctggtct gtgccgacag cctgcagcgc cggtccgact
     8401 tgtagccctt gtagtgcgac cgtgccggta aatggcggag tgggagttcc caggcctaac
     8461 gttccctgcg tgcgcaggaa gcctccgaag acttggagcg tgaggttggt gagtcgcgcc
     8521 tcttgcccct tcatttcggc cgccgcctgg aggtctttga tctctacggg ctttttcaag
     8581 ggcaatgcca caggcaaatc ggcgctgttc acgagttttg aggtcgccgt caccttcgcc
     8641 agtccgccga gcaccgatcc cttgacctcg acccgtgagc ttcccaatgc gatcgtcagg
     8701 cccaggttcg gcacctctgc gagctcaagg ggcgcggtgc cttctttggg cggatacttc
     8761 gcccgaacgt tcatgtgcag gtctttcact tcgactggtt tggctagtgg gacggccact
     8821 ggaaggtcgg aggaattgat actggccgac gccgcggtga tattggcgag gcctttggtt
     8881 gccgtgccct tgatgttgat ggctgagcca cccatcacca gggttaggcc caagtccgtc
     8941 aggtctacct ggctggcggg cggggtatca ggcgggatcg ggtagagagc atggagcgtg
     9001 agatgcagat ccttgatctg gacaggcttt gtgagcggca atgcgatggg aagatccgcc
     9061 gtatcgattt gcaacgcatt aatcgtggca tccaggttgc cgccgactgc gcgtcctttg
     9121 agccccactg cgaccttgcc aaggccgagg ttgaacgaga aggatttcac atccagcgtt
     9181 tcaaccagtg gtccgaatgt cccatccaga tgcacgggaa gattataggg caggacggtt
     9241 gctcccaggt gcaccgtggg actatcgccc agatggaccg acgtcagcaa aaattccagc
     9301 tgggtgacgg tgtactccgt cggcttcgcg gtggactcgt cacgatacgt cagcttcccg
     9361 ccatcgatcg aaacccggtc gacggcaaaa agcgccagcg cttggagtgg gctgccggcc
     9421 ggttgtcctg gggcctcggg ctttgagggc gcggcaggag acgtgggttt cgcgccgatg
     9481 gtagagatgt tgagctgccc ctgcgaattc ttcaggacca gaatgaccgg gtcgcgcagg
     9541 gtgatctctt ccacatcgac tctgcctttg agcagcggca ggagcttgac gcccacatcc
     9601 agcgacgcga gagaggcaaa gggccccgtg cggaacgccg ggtcatcctg gacaacaaac
     9661 ccgccgattc gagccccgat gcgtggccaa atggtcagac ggatatcctg cagttcgact
     9721 ttccggttga gcgcctcctc aatcaaaggc cggtaccgat cctgatactt gttcaaatcg
     9781 atgaggaaag gcaaagcgat gatcaggatc agaaggagca ggatcacgac accgatcccg
     9841 accagaattt tcatcacgta cctccgctga aatggtcccg cagtatagga atgcgcgcga
     9901 aatcggtcaa tggcggcaaa tcggccttgc ctcgcacgac gtcgcgatgg aaaacccccg
     9961 tcgtggtctc tccgccgtgc cgtttcgaga tcgagtctga ggtaagggac gtggcgtccc
    10021 ttaccttgcc gctcaccggc ctgcgtgata agatgccacc ctttgaagtc gtccgatcgc
    10081 ggagaggtgc gagagtggac gaatcgacat gcttggaaag catgcgtctc ggcaacggga
    10141 ccgtgggttc gaatcccacc ctctccgcca tcgaaagtgc gaagtaagat tgggaaggcg
    10201 tgcgagtcga atgaccattg ccggctgagg cggtgggatt cgaacaaggg ggaatcgcgg
    10261 gggagggact cccctgcgtg gggagacacg agggggcagg ccccctcagt gggagcgcgt
    10321 atgcgtgact tcgaatgccc accctctccg ccatcgatta gagtcgtgtc acgtcgggca
    10381 tgacgggaac cggtatgaga agggggagtc atacaaggct ctgccctttg cctttcatcc
    10441 ctgccggatc acgaaatcct cggggccggg ccctgtgcaa cagaaccctg tgaaccccgc
    10501 caggtccgga aggaagcaac ggtaagcggt tcgttctgtg tgccgcagga tcacctggcc
    10561 ccactttttt agacgactga gccacaagtg gaagaatgtc tgctctggcg tcccgaactg
    10621 ccactcgaca cacaatcgtc actactagtt agagcctgac gaaattggat taccaagtct
    10681 ctgcaagaaa ataccggcct ggaacgtttg atgatgtcat cgggcagtca cacgtcgttc
    10741 agacgttgat gaattcgatc gccaccaagc gaatcgccca cgcctttctc ttttcgggca
    10801 cgcgtggcgt cggaaaaacg acggtcgcgc ggatcctggc gaaggcactc aactgcgagc
    10861 agggtccgac cggttccccg tgtaacacct gtgcgaattg tcaggaaatc acgcagggta
    10921 cgtcggtaga tgtcgtcgaa atcgacggcg cgtcgaatac gagcgtggac gacgtgcggg
    10981 aaattcgcga gaacgtcaag ttcaccccgt tccgaggaca gtatcgtgtc tacatcatcg
    11041 atgaagtgca catgctctcc aactcggcgt tcaacgcttt gctcaaaact ttggaagagc
    11101 ctccgtccca cgtcgtgttc atcttcgcga cgacggaaat tcacaagatc cccgcgacga
    11161 ttctctcgcg ctgtcaacat tacaactttc gccggatttc aaaggctgag attgtgcagc
    11221 ggctgcggca tgtggcggac caggatggct tgaccatcga agatcgaagc ttgatggccc
    11281 tggcgcgtgc cagcgaaggt agcatgcgcg atggcctcag cttgctggac caagtgattg
    11341 cgttcggcgg caagacgatt cggcatcacg atcttgaaac cctgctcggc gcggttccgc
    11401 aggagcgggt gcgggcgatg gttgaggccg tgatcgacca gaacagcgcc aaagccttgc
    11461 aggtcatcgc cggactcttg gatcaaggcc acgacgtccg cgcctactgc gccgatctgg
    11521 tggagtatgt gcggaatatg ctggtcgctg ccgtagtgcc tgcaggtccg gagttgcggg
    11581 gactgatcga agtgaccgat gaagacctga cgcaactggc tcgggacgca gaacagtttt
    11641 cggtggagca cctccaggaa ttatttcgat tgtgggcggc ggcagaggat catctgcggg
    11701 tcagcgccca tccccggttt gtgctggaaa cggctgcggt tcgtgcgact cgtctcctgc
    11761 gcgcgcctga atccccggcg gggttgccgg gagtgaatgt tcagtcaagt gcaacgcctg
    11821 tcgatcgggc aacgggaact cgcacatcga tgtcatcatc ggagaaggtg gtgtcaccca
    11881 aacccacgaa acgtgatacg gtgaaaagca gctctgacgc cggagacaaa ccggttgttc
    11941 cgagcgcatc ggctccggcg ccggctcctg ttgcgcgtcc tcgtgaagcg gtggttccat
    12001 ccagtcagac tcctgctcct tccattccat ctgcgcaggc ctccgcgacc gcgcaggttc
    12061 cggtcgagtc ggcgtcgcca aaacccgaac ccccgtctca cagggcaacc gcctcaccct
    12121 cggcagagat taattgggag gagtttcaag aggccgtttc gggtcagcat cccaatattg
    12181 cgccgttttt ggaaatgggc cgggtagtga agattgaagg tggattggtt acgttgggct
    12241 ttaccaaaca ggcgacggtg gcgcgagcca tgctggagaa ggaagacaat cttcagtccc
    12301 tggcggcgtt gggagaacga atatacggaa ctgccttgcg tgtccgaatt atcgaagtgg
    12361 cggagcagga tccggaggcc acccccacga tgaagcaatt acgggttgcg aaggagcagg
    12421 agcagcgcgt catcctgaca caacaggcga aggcgcatcc tctcgttaaa caagcgctgg
    12481 agatgttcgg cggagagttg gccgaggttc gcacgacaac tccggcacag gaggtacagg
    12541 aatgaaaagt ccattcggga atatgtccaa cattttgaaa caagcacagg ccatgcagga
    12601 acaaatggct aaggtgcagg agcaggctgc gaccaagacg gtatccggga ccgcgggtgg
    12661 gggcattgtg actgtgaccg tgaacggcgc aatggatctg ctgagcgtga agatcgatcc
    12721 ggaagtcgtg aagtctggtg atgtcgatat gttgcaggat cttgttgttg cggcgggtaa
    12781 cgatgccttg aagaaatcac gcgatatgat ggctgaggaa atgaaagccg tcacgggtgg
    12841 aatgaagatt cctggtctgt tctgatgcga tcgagattgt gttgtgtcga atgcgggagg
    12901 ctatgggcct ctcgtgtgtg tggcctggat gtgacgatgc gctatgagta ttgatcagca
    12961 gggactgttg gcaaaattgg ttcgtgagtt ggtgcgtttg cccggaatcg gtcagaaaag
    13021 cgcgcaacgg ctggcgttcc acctgctcaa ggcggagcgg gaagatgcgt tgcgcttggc
    13081 cgaagccatt caagccgtga aggacggact ctcgttttgc cgccaatgtc gcaatatcgc
    13141 tgagggggag ctctgtgagt tctgccggga ttctaagcgg gatcgcagca agattctcgt
    13201 ggtggaagag ccgagcaccc tgtatgcgat agagcgcgcc ggtgggtacc ggggtttgta
    13261 ccacgtcttg ctcggagtct tatcgccatt ggatggcgtc gggccatccg atattcgcgc
    13321 ggaggaattg cttgagcggg tcaaagccgg aggtgtcgaa gaagtcatcg tggccaccaa
    13381 tcccacgatt gaaggtgagg cgacggcgat ctacctgacg cgactcttga agcctcacca
    13441 cgtccgggtc acgcggattg cctatggaat ccccgttggg atggacatcg agtatgcgga
    13501 tgaggtgacg ctggtgaaat cgatcgaagg ccgacgagat ttgtgacgca gacgtcccgc
    13561 tgcctttgag agtgcccagt tgcggataat cctcatcctc gcccccaccc cagacgaacc
    13621 gattgacccc tccgatttgc ggctgctata gtcggaactc gttgggcggt ctggcggcga
    13681 taccggccta gtaaaccgag tattcaatga agacttcggc gaagaaatcc actcccaccc
    13741 gaaagaaacc tgcgaaggcg aacggggtta agtatcctga tattcagaaa gacctcgagg
    13801 gccaacgtgc cgctatcctt gccgaagccg gagtggtgct gacgaaccct accggtctgg
    13861 aagtgtttcc ggatgtgagc gaccaagcct ccgccgaagc ggatcagcat ttctcatttc
    13921 gcattcgcga acgggaacgg aaactcctta agaagatcga tgaagctttg gggcggcttg
    13981 ccacgcatac ctacgggatc tgcgaaggtt gccagggcga tattccctat aagcgactga
    14041 aggcgcgtcc ggtcacgacc ttgtgcatcg aatgcaagac cagtcaggaa gaagcagaga
    14101 agtctccccg ctgattcggt tctgtcccct tcgaattcct tttgtgacac gcaggatttt
    14161 gccgcacagc acccgtttca ttactggtgt ttgagggctt tgacgcgtga ttgcgccagg
    14221 gctgagcgat ccgcttcttc cggaatgccc tcagtaagcg ccagatacgt ctcatattca
    14281 ttgatagcgc gtctggggtt agcctccgca atggcctcgg ccaggttgaa ccgggcaatg
    14341 gcgtaattcg ggcgcatcag cacagctttt tcgaaggacg cgagcgcgtt ctgcttctcg
    14401 cccagcttgc catacacata gcccagatta ttgacgacct ccggggagtt gggacgttgt
    14461 gccagtgagg cgagcagttc gcgcttggcc ttttccaagt cgccggcagc ttcccaggat
    14521 acacccagcc ggtgatgcag ttccgcttgc cagacctggc tggtgaatcc tgaagcgctt
    14581 gccttctggt aggcatcgag cgcgatggtc tgatttttcg ctccacagta tgcgagttgt
    14641 gcggtttggc ctcgggcgaa ttgttggagc gaggcgaaag gctccttgtc ttccgcgccc
    14701 tgcgtgtcga ggtgttggcc accgctttgc tgtcccgtat cccgcagccg atcgagaaac
    14761 tctttccggt agggagagaa gagcttcacg tacggatcaa tggaaaagga cgcagccaga
    14821 agctgcggat tctttcgatc gcccaggacg agataccggg tggtggtctt ctcatcgccc
    14881 gtgtcataga gggtgctgga ggccatattc tgacgatccg ccaattgagc gacggtcagg
    14941 tagaactcca ggctgggttt cagttgggtc agggtatagc gaagcgtttt gtacggaccc
    15001 aagtcgagtc cggaccgaaa gatgaacagc gtcccgacca gtgtcccgtc ttcatcgaag
    15061 aagtacgact cttcgccctt ggacaggctc tgttcggccg aaaagcgcag ctcttgccca
    15121 ctgccccacg cttgggtttt cggaacgatg ccaggatggt gctcttggaa caccttgcgg
    15181 gtatcgcaaa gtttcgtgga tttcaggagg tcgaggtcac tttccgatgg cggaagcggc
    15241 gcacgggctg gcggcggagt ttcgcaccct gtcagcaggg cgaacatggt gagcagtgca
    15301 ggcagcagtg agagccgacg gtgcatggcc ggaatcgatg ccccaggtca atgccatata
    15361 ggatcgagga atagagcata cctgaatggc tgtagagatg cgactggcag gcggagtaat
    15421 gacaggcttc tcctcgccgc cgagaaaaga tcccggcagg cgaggggtgg agcaggttac
    15481 cgacgttgcg agtcgatcat agaatcttcg gccgtgtagc cgaagaggta cggcgcatgt
    15541 ctcgcaatgg cgtagagtgg ccgattcacc gtgtagtcta cgagatgccc gaccgggtgg
    15601 agcacaaagc ccagccatcg gtaaggattg tcgttcgcct gtgaggcggc catgggatcg
    15661 gaatagacca gggaggtgct gtccatcgcg ctatagatgc tgagcggcgc gttgtagttc
    15721 tggtcctgcg tcgccacctg attggtggtg gagcagcccg tggtcagaag cagtcccaac
    15781 atgattgtgg ccaaagtccc gcgcataccg tgcctctctt tcttctatag gaacattcga
    15841 agagacgaag tctgttcctt gtgagaaaag tctagcgcag ggtcctgatt ctgtccagtt
    15901 ggacggcacc ctaggtcgtc gttcaagctg tctcagctga tcgctgtggc aattgacata
    15961 aaatatgagc agtttcaagt agttgagaga ttcattcgtc cgtagtgatt acatgcggtt
    16021 tcgagtgcga ggtcatcgtt ccaaatgaat cctgggagat ggcctgtcct ctcgtgtaac
    16081 tgtcgggctt atcctcatgt tctaagggat tccaaagtcg tcttgcatca agaagctact
    16141 ttttgtagtc ctcgttgctc tgattaagtg cattcatcgc ccctccgccg gcaagcgcct
    16201 aatcgattgc gcacaagtcg ccgatgatga cgcaacgcta tgcgcatcat tacccggaaa
    16261 gcctgcgaga tggagtggag attttggacc gacggtcaca ccgtgacaca aaaatgacca
    16321 cagtgttgta gggattgaga gtgttattcg gaaggggttg aaaaattggt gggcgataca
    16381 ggtatcgaac ctgtggcctc ttccgtgtga aggaagcgct ctcccactga gctaatcgcc
    16441 cgagcaggac gggagtctac cacggtccgg caaacaggag caaccaactg cccgacggcc
    16501 ataggtcctc acgcagggag ctctcagctc gtccgccaag gctaaatcgt ccttggtttt
    16561 cttgacatcg agaaaaggcg attcttacaa tgagcctcct tccatctttt caaaggtttc
    16621 ccattcatgc gtgaagacat cgtcatcatc ggtggcggtt tggccggctc agaagcggcg
    16681 tggcaggcgg cacatcgcgg agccaaggtg acgctctatg agatgcgtcc gaaagagacg
    16741 acgaaggcgc acaaaaccgg cgatctggcc gaacttgtct gttccaactc gctgggatcg
    16801 atggatccgc tcaatgcgcc cggcattctc aagggcgaga tgcgtcgcct gaactccctg
    16861 gtgattcgtg cggccgagga ggcacgcgtg ccggccggtt ccgcgctggc ggtggatcgg
    16921 gaaatcttcg cacgggccat cacgcaagcg ctggaagggc atcccaatat tcggatcatt
    16981 cgcgaagagg tgacggaaat ccctgcggat gccgtcgcga tcatcgctac cggcccctta
    17041 acgtcagaaa aattgtccaa agccatcagc gaactcactc acgaacggca cctgtatttc
    17101 ttcgatgcga tctcacccat catcgacgca gactcgatta acatggatat tgtgtatcgt
    17161 gcgtcacggt atgggaaggg cggcgcggac tatctgaact gtccgatgga tgaggcggcc
    17221 tacaatgcgt tgtacgacgc gatgatggcg gccgaaaaag tgcagccgaa agagtttgag
    17281 aaagtcgcct actttgaaag ctgtattccg atcgaagtca tggctgagcg ggggcggcag
    17341 actatgcagt tcgggccgct caaaccggtc ggcttggacg atccgaaaac cggccggcgc
    17401 ccttatgcgg tcgtgcaatt gcggaccgaa aacgttcatg gcacctgcta caacatggtc
    17461 ggctttcaga ccaagctcac ctaccccgaa cagaagcgag tctttcggct gattccaggc
    17521 ctggaacagg ccgagttttt gcggtttggc agcctgcatc gcaacacctt catcaactcc
    17581 ccgcagctgt tgcgcgacac gctccagctg aaaacccgcg ggaccgtctt ttttgccggc
    17641 caactggtcg gtgtcgaggg atatacggag tctgcggcga tgggtgggat tgccggcatc
    17701 aatgcggcac gaggtctcgc cggtcaacca ctcgtgaccc cgccgcctac cagcgctcat
    17761 ggttgtctga tggcgcacat caccaaaagc gatccggcac attttcaacc gatgaatacc
    17821 aacttcggcc tgttcccgcc cgtcaccgtc aagacccgcg acaaagatca gaagcggcgt
    17881 ctcatccagc aacgagctgt tgaggatttt gacgcatgga tcgcgcaatc cgggctttcc
    17941 tagacgtgtt ggcggttcag gacgacgcct ctccgcaaac gatccgcgcg tatacgtccg
    18001 acctggctca attccgcgcc tttgccctgg ctgcgctgaa gcctcgtgac acattaacgg
    18061 tcgaatcgat agaagcgggt ctgattcgtg aattcctcgc ctcgcgtgat cgcaaggggg
    18121 agaagaaaac ttctctcgcc aggaaattag cctgcctgcg aagtttcttt cggtatctgg
    18181 ttcgcgtcgg ccgcgtgcag gcgaatccgg cggaagatgt gcgcgcgccg aaactgccga
    18241 aacacctgcc tcaagtgctc acgaaagacg atgccggagc gctgatggaa tttccgccgg
    18301 gagacgcacg cgagggtttg cgcgaccgtg ccattcttga aactctgtat tccaccggcg
    18361 cgcgtgtcag tgaattggtc ggcatggatc ggcaggacat cagtcgcagt gaaggtgtcg
    18421 tgcgtgttcg cggcaaggga gggaaagagc gagtgatccc cttgagtcca ctcgccctgg
    18481 aggccattga tgcgtaccat gcgcaggcgt ccgtcacagc tgcttcgaat tcttcggatc
    18541 gaggggcgcc aggcggctcg cccgtttttc gcaatcgccg cggagggcga ttgacgacca
    18601 gaacgattgc ccgcatcgtg gcgaaatatt cgggacaact gagcggtggc gcgattcacc
    18661 ctcacacgct gcgacattct tttgccacgc atctgttgga tgaaggcgca gacctgcggg
    18721 ctattcaaga aatgctgggg cacgtgtcgc tcagtacgac tcaaaaatac acccatcttg
    18781 cgacggacca gctactcgcg ttatacgatc gcactcaccc gcgcgcgggc gctgcgggtg
    18841 aagcggaaca agggaataag cagaagggtt cgcgatgaag attcgatcga cgacagtcct
    18901 ctgtgtcaga cgaggcaatc aggtgacgat ggggtgcgac ggacaggtca cggtcggtac
    18961 caccgtcatg aaacataacg ccaggaaaat gcgccggatg cataacgaca cggtcttgtc
    19021 gggattcgcc ggtgccacgg ccgatgcctt caccctcttt gaaaaattcg aggcaaaact
    19081 ggcggagtat cgcggcaacc tgacgagagc cgccgtggaa ttagctaaag actggcggac
    19141 ggaccgcgtg ttacggcgtc ttgaagcgct gctggccgtg gccgatctcg atcactcctt
    19201 tattatttcc ggaacgggag atgtggtcga gccggaggac ggtattctcg ccatcggatc
    19261 gggcggaccc tacgccctgg cttccgcgcg agccctgctc gcgcactccg aactaggcgc
    19321 cgagcccatc gtgaaggaat cgctgatgat tgccggcggg atcgacattt ataccaacca
    19381 acagattgtg atcgaatcgc tcacgcgtta ggatc
//
LOCUS       DAOQPD010000076        19311 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1419_length_19311_cov_20.300374, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000076 DAOQPD010000000
VERSION     DAOQPD010000076.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 19311)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 19311)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19311
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1419_length_19311_cov_20.300374"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..2925
                     /locus_tag="PK063_14895"
     CDS             <1..2925
                     /locus_tag="PK063_14895"
                     /inference="COORDINATES: protein motif:HMM:NF012398.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline dehydrogenase family protein"
                     /protein_id="HMZ98385.1"
                     /translation="ARRSSGLSPGLFDSRWWSQAAINLAMKDPAFKAQLFRFIDVLPS
                     LRDDAQVVRLAEEYFGDMSGHLFGAQWGLKALASTKLGAALSGKAIRHQVEQMATSFI
                     AGASIEQAVPALRKLWDDGRAFSVDLLGEASVNEREADAYRDRCLAALRILGDVCPAW
                     SPSPLLEHDHLGPLPRVQLSIKISALYSQLDPIDPESSYRAVAARLRPLLNVAGTLPA
                     SIIFDMEQAETKDLILSIFMRLFEEEPYRTFAHAGIALQAYRIDTYDDVQRLLAWTTR
                     RQVPITIRLVKGAYWDSDAIRYRQRGWPMPLFEQKSQTDVNYESLVRLLLEQSHLIRP
                     AFGTHNLRSLAVIEAVAEALGLPPVAWEYQMIFGMAEPFQHAMSDRGRRLRLYTPVGE
                     LLPGMAYLVRRLLENTSNESFLRKEYVESQPLSLLLSPPDGAPSHPAYSSPVEHKSSP
                     YTSPTEFVNEPVADFSRASARTAMADAIERRRKHLGQRLDLSTLAAHLPTGPDLSTRN
                     PSHPEQIVAVVQSYQPADVAALTKIAGAAEESWTRRPVADRVAVIRKAASLMRDQRWD
                     LAAWEVFEEGKPWREADADVAEAIDFLEYYAGEMARLDPPPRLGRYPGELNEVLWNSR
                     GVTVVIAPWNFPLAIPTGMVAAALVAGNPVLFKPSERSSAMGYQLARILLDAGVPKGL
                     LQYIPGGPELGRELVVSAAVRTIAFTGSKDVGLGIMQAAGVQQPGQRFVKRVIAEMGG
                     KNAVIVDETADLDEAVTGVVQSFSGYAGQKCSACSRVIVVDSIHDAFLERLADAVMSL
                     RVGPADDPATQVGPVIDARAKQRILDYLEIGRREGRVLVDRSAEGPGYSVGPVVIADI
                     EPVHRLAQEEIFGPILAVMRVASFEQALEYANGTAYALTGGLYSRSPRHIARAREAFD
                     VGNLYINRPITGALVSRQPFGGHRLSGVGAKAGGEEYLKQFLVARVVSEQTLRRGFVP
                     TL"
     gene            complement(2815..3717)
                     /locus_tag="PK063_14900"
     CDS             complement(2815..3717)
                     /locus_tag="PK063_14900"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98386.1"
                     /translation="MVQNLFRSTLIAVGILGSAAILVGHDTASATEAGQAIAQSADYF
                     PDTIGTRWQYRGQISEGPLQTIENKYFSNVSSVTGTRTLKGGLVVTVFHDTNPGNHGP
                     SDSFYRRDAAGVVYYGSEPGTPLEKQLTPYQIIRFPMKVAQSFQQFNRTDIDFGSDID
                     GDGTNEKVDVEGLSTVLGQESITVPAGTYPDAVRVEAKMTLKIRLSSVDRTAVGTDVM
                     TAWFAKGVGLVKYIERQELAALKDDRGNITDITEELEEVSVKSAPGLQGRHESAPEGL
                     LADDTSNQKLFQVLFASGLRAYAR"
     gene            3824..4585
                     /locus_tag="PK063_14905"
     CDS             3824..4585
                     /locus_tag="PK063_14905"
                     /inference="COORDINATES: protein motif:HMM:NF024950.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HMZ98387.1"
                     /translation="MQSEPQTSASSPRELRTVLVTGGSGGIGRALCLAFARAGYWVGV
                     HYGRHKEAAEETLRELSTDGGAGAIYQADIRSGLEIQAMIDAVLDRQDRLDVLVCNAG
                     VASSHLVLRCPEDEWLRIIDTNLTGTYRCLTAVAPLMIKQGGGSIIVVGSYAGLHGAS
                     GQAAYAASKAGLVGLVQTAAREWGPHNVRVNLVCPGWQPTALAGDAFPSTEQLSDHVL
                     GRLMNLEDVSRTICHLAQLPGMSGQIVNLDSRILY"
     gene            4609..5355
                     /gene="bioD"
                     /locus_tag="PK063_14910"
     CDS             4609..5355
                     /gene="bioD"
                     /locus_tag="PK063_14910"
                     /EC_number="6.3.3.3"
                     /inference="COORDINATES: protein motif:HMM:NF024891.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004141 - dethiobiotin synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dethiobiotin synthase"
                     /protein_id="HMZ98388.1"
                     /translation="MIGTTGVFVTGTDTGVGKTLVAAALVNRLVRMGRSVGVMKPVET
                     GVDAGLSDRTDAARLMAAAQVTDSLDLVSPYRFPAPVAPLSAAAAQGRVIELGDIVGR
                     YEQLAARYPCVVVEGAGGLLVPTGSDWAMADLISRLRLPVLLVGRVGLGGINHALLTL
                     EALERRNIPVVALVLNETVAPRGSVEQEQAASTVALLRDRVSMPLIGPLPYQTRADCA
                     WPEVVENVAGSRPISDLAELVWKAAAGSSG"
     gene            complement(5303..5917)
                     /gene="thiE"
                     /locus_tag="PK063_14915"
     CDS             complement(5303..5917)
                     /gene="thiE"
                     /locus_tag="PK063_14915"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HMZ98389.1"
                     /translation="MLDPTVRPERPLTDVLRVAAASGIRLFQYRDKQASMKDAYRQAL
                     ALRQVATEVGATLIINDRCDLALAVKADGVHLGQDDLPLADARQILGPEAIIGLSTHN
                     AKQVREAVALQPDYIGFGPIFGTTTKTDHDPVVGLEGLRAARTLTTLPIFAIGGITSQ
                     HVTDLTAAGADGVAVISAILKAQDLEAAIRSFQPPPSTQARPSH"
     gene            complement(5990..7339)
                     /gene="accC"
                     /locus_tag="PK063_14920"
     CDS             complement(5990..7339)
                     /gene="accC"
                     /locus_tag="PK063_14920"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HMZ98390.1"
                     /translation="MFKKVLVANRGEIALRVIRACKELGIKTVAIHSEADAASLHVRA
                     ADEHVCVGPPEAALSYRNIPNVLSAAEVTGADAIHPGYGFLSENAHFAEVCESIGVKF
                     IGPTSENIALMGDKSKAREVVAKKGLPVTPGSPGELRSEQDAQEAAKNIGFPVIIKAS
                     AGGGGRGMRVVNKPEELTRAFQAAQAEAKSTFGHDGVYLERYFLEPRHIEVQIVADNR
                     GHVVHLGERDCSIQRRHQKLVEETPSPAIDERLRREIGRTAVEAVKAIRYCNVGTVEF
                     LLDKDRNFFFMEVNTRIQVEHPITEMVTGIDLVKEQIRIASGLPLSFKQPDIKLNGHS
                     FECRINAEDPEKFTPCPGQITKYSAPGGLGIRVDSAMEPNAVVVPYYDSLIAKLITHG
                     RDRQEAMARMRRALDEFVIEGIKTTIPLHRKIFNDPDFQKGHVSTTFLDRFLAGQSA"
     gene            complement(7517..8095)
                     /gene="accB"
                     /locus_tag="PK063_14925"
     CDS             complement(7517..8095)
                     /gene="accB"
                     /locus_tag="PK063_14925"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014961241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HMZ98391.1"
                     /translation="MSPSRKKTGKSRTAAKPIVLPSAFAPRTSAADQMILNPDQAAQI
                     QQLADLLKRNHLTELEIERSGMRIRIRHEPAVRATTTHTVEAVHTQSATSGTAPAAQA
                     RPSAETDGQVTITSPIVGTFYRSPSPDADPYVEEGDYVKKGQVLCIVEAMKLMNEIES
                     EADGRITKILAESTKPVEYGQPLFLIDPSATP"
     gene            complement(8092..8652)
                     /gene="efp"
                     /locus_tag="PK063_14930"
     CDS             complement(8092..8652)
                     /gene="efp"
                     /locus_tag="PK063_14930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HMZ98392.1"
                     /translation="MISTAEFRNGSPLMVEGQPFYIVEFQHVKPGKGGAFVRTKLKSY
                     LSGNVLDRTFRSGEKFDTPEIEECDMQFLYATNDSYTFMDTETYEQSTYEKSQLGSNA
                     DLLKENMIAKILIYEHKPITVVLPNFIELKVVDGEPGVRGDTASGGSKPVIVETGATI
                     KVPLYLEIGEVIRIDTRTREFVERVR"
     gene            complement(8678..9175)
                     /gene="aroQ"
                     /locus_tag="PK063_14935"
     CDS             complement(8678..9175)
                     /gene="aroQ"
                     /locus_tag="PK063_14935"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II 3-dehydroquinate dehydratase"
                     /protein_id="HMZ98393.1"
                     /translation="MLRLLVLHGPNLNLLGTREPSVYGQMSLSDIDKSITRRSGELGI
                     AVQTKQSNSEGELVTWIQNARGHFDGIIINPAAYTHTSIAIRDAIAAVALPTVEVHLS
                     NIHQREEFRHHSFIAGVAIGQIAGFGPTGYLLALEALTVHLGAKRSSSRTRADVRKKP
                     AASRR"
     gene            complement(9298..9984)
                     /locus_tag="PK063_14940"
     CDS             complement(9298..9984)
                     /locus_tag="PK063_14940"
                     /inference="COORDINATES: protein motif:HMM:NF025910.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ98394.1"
                     /translation="MSSPLRIPPAIAAEIDRLATAVAKDPRSKDFLPLADEYIKAGMW
                     QEAAAVLEDGLKVYPGFVTAMAALGRVYDQLGQAEKAKVILEEVVKQRPDNLRAHRIL
                     AKLYHAEGQADLALRSCTAILNANPFDEEALAVKRSVTGAPDEPPPSKREKKRSLAEA
                     PVEKITAAVPPAPAPVVLVSESAAPTVSMPDPTPPQSPPSPAVQHAAAIARLEAWLST
                     IQAKRHPAAR"
     gene            complement(10027..11241)
                     /gene="coaBC"
                     /locus_tag="PK063_14945"
     CDS             complement(10027..11241)
                     /gene="coaBC"
                     /locus_tag="PK063_14945"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0015939 - pantothenate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HMZ98395.1"
                     /translation="MHTTGPSLSGVRLVLAVTGSIAAYKAVSLLRLLRREAATVNVVM
                     TAGACRFVTPLTFEVLSGTHVATDLFEAHQEMLHLSLPEQAQAIVIAPATANCLAKAA
                     LGLADDLLSTMLLTTQCPVIFAPAMDGDMWQHPTVVEHVATLRARGAIIVEPEDGPLA
                     SGRQGQGRLADEERILAAVHHAVHPRRDWSGRKVLISAGPTQEAIDPVRFLSNRSSGK
                     MGYALAEAARARGADVVLVSGPTSIPVPAGVEYCPVITAEEMHKALTTQLDWSDTVIM
                     AAAVADFRPARPSAHKIKKRRGPVTHLDLEATDDILCELRDRRTSQVLVGFAAETDDL
                     LAHAKEKLHAKGLDLLVANDVTAPGSGFGSDTNRVWLLAREADPEELPLLSKRDVADR
                     ILDRILTVHTGR"
     gene            complement(11251..11613)
                     /gene="rpoZ"
                     /locus_tag="PK063_14950"
     CDS             complement(11251..11613)
                     /gene="rpoZ"
                     /locus_tag="PK063_14950"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: protein motif:HMM:NF013365.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000345 - cytosolic DNA-directed RNA
                     polymerase complex [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HMZ98396.1"
                     /translation="MGEMLSLLPEYATGEFDSRHRLVIVAAQRAKQLVQGARTTASSK
                     FTKETSIALDEVLRHNVKFLVGKEARDAIKESKRVKEGETERLAMMTGEDAKEIKKEL
                     SVYVDDTAKPVAAPEAEE"
     gene            complement(11606..12322)
                     /gene="gmk"
                     /locus_tag="PK063_14955"
     CDS             complement(11606..12322)
                     /gene="gmk"
                     /locus_tag="PK063_14955"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HMZ98397.1"
                     /translation="MSTAPVPSHDKPAQVRRGILFIISAPSGSGKTTLCKQITANVPG
                     LWHSVSYTTRKPRPGEIDGQDYHFLDEASFRQMIDRNEFVEWAHVYGNLYGTPRKELT
                     EKMEQGIDVLLEIDVQGARSVKKKFEDGVYIFILPPSFDTLRTRLQNRAGDSPEEIQR
                     RLQKAKEEVWSYREYYYIVRNDDLKQSLKELESIFLAERIKTKRLNMTWLEEKFILDK
                     EGKQGNSSSAPASKEHMHHG"
     gene            complement(12353..13231)
                     /locus_tag="PK063_14960"
     CDS             complement(12353..13231)
                     /locus_tag="PK063_14960"
                     /inference="COORDINATES: protein motif:HMM:TIGR00255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HMZ98398.1"
                     /translation="MIRSMTGYGKKDGTSQQATVTVEIRSVNHRFLEVAVRVPRSLAQ
                     LEDPIRKAVQQRCLRGRVDVSVSVQTAGGSLKTVHIDQVLAKQYHTALKKLQKTLGLR
                     GGVDLSMVAGFRDIVSLTDEPVDTDHLGKTLLRVLGGALTELEKMRKREGEALTKDLT
                     LHLDAIREAQSIVAKKAPDLAKIAFDRMKARIETLLQSEVPDPARLQQELAVYADRSD
                     ISEELVRLESHMVQFDQQLRSQESVGKTLEFLLQEMGREVNTIGSKANDAEIAALVVR
                     MKAELEKLREQVQNVE"
     gene            complement(13228..13899)
                     /gene="nth"
                     /locus_tag="PK063_14965"
     CDS             complement(13228..13899)
                     /gene="nth"
                     /locus_tag="PK063_14965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003906 - DNA-(apurinic or apyrimidinic
                     site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HMZ98399.1"
                     /translation="MKAATAHHVSAQPDKRRLARMLRALRATEPARKVELDYRTPWEL
                     LVATILSAQCTDQRVNQVTPALFRRYRRPQDYAAADAAELEALIRPTGFFKTKAKNLI
                     HCAKAVVEIFHGQVPETMEALTGLPGVGRKTANVLLGNAFDKPAIVVDTHVKRVAGRL
                     HLTRHTDPEKVEMDLQQLLPAAEWTEGSQRLLLHGRYVCLARTPKCGNCAIYTDCHWE
                     GKLTR"
     gene            complement(13934..15430)
                     /gene="hflX"
                     /locus_tag="PK063_14970"
     CDS             complement(13934..15430)
                     /gene="hflX"
                     /locus_tag="PK063_14970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HMZ98400.1"
                     /translation="MGAGCAPTFESLAKFRVGSHSLRGLRLIRTHLHDEPLSQDDLTH
                     LALLRLDLIGALGVTETGEPGLLHLAHLLPPNQQGEVCRLLKPVPFHDLELQLDTFLH
                     TLESDLQRSDTQHTVTGGQESAILVSAAPKGHAEQDEHLEELTELAESAGVRVLDRIA
                     QRTHEGYERYLLGKGKLKDVVMRSLQKGADLIIFDQDLAPAQARAISEVTDLKVIDRT
                     QLILDIFARRAHTREGKVQVELAQLRYLLPRLSGHGTSLSRLGGGIGTRGPGETKLET
                     DRRRIRDRIAHLEREIDHVARHQDQRRARRVRQGLPILSIVGYTNAGKSTLLNALTQS
                     QISAQDRLFETLDTTSRRLRFPHDREVIVTDTVGFIRDLPKDLVGAFRTTLDELRDAD
                     MLLHVLDASASNLDQQIAAVDAVLQSLQLDTIPRVMVLNKCDRLSPREADVLSQRYHA
                     IAISALDRETLRPLIAHLEALLPAVPSPPSHEADTELPPQERALASHS"
     gene            complement(15654..16724)
                     /gene="tsaD"
                     /locus_tag="PK063_14975"
     CDS             complement(15654..16724)
                     /gene="tsaD"
                     /locus_tag="PK063_14975"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HMZ98401.1"
                     /translation="MTHAASATILGPILGIETSCDETAAAVLDGEGHVLSNIISSQQA
                     VHERFGGVVPELASRAHIQNIDQVTGRALEEAGLGWRDLRAIAVTQGPGLAGALLVGL
                     SYAKSTAYALDIPLVGVSHLEGHIASAWINRPAFPRDCVVLIASGGHTHLFHAEEKGG
                     FHLMGRTIDDAAGEAFDKGAQMLGLGYPGGPLIDAAARKGRPTAVRFPRSRVRTGQFD
                     FSFSGLKTALLYHLQGMSLEAIAEQQTDLAAAYQEAIVDVLVRQAFAAVERAGVSALA
                     VVGGVSANSRLRARLAERAVKEGIELSLPALSYCTDNAAMIAAAGQRALLQGNVASFD
                     CEAMPDCALPAWSGSGVVRRTS"
     gene            complement(16973..>19311)
                     /locus_tag="PK063_14980"
     CDS             complement(16973..>19311)
                     /locus_tag="PK063_14980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HMZ98402.1"
                     /translation="HLVLAILRETDGIALMILKKMGLSTEQIRLEIERNLPGGGTTMT
                     FGEIPFSPRVKKVIEYGVEEARLLGHNHIGSEHLLLGLLREEEGIGGKILRSLGANLL
                     TARQLTVTFLRKSAPRERDRKSNTPALDEFGRDLTQLAQEGQLDPVIGRADEIERVLQ
                     ILSRRSKNNPVLIGESGVGKTAIVEGLAQRIIASEVPDNLLSRRVIALDLGSLVAGTK
                     YRGQFEERLKVVMKEIVQAGNIIIFIDELHTLVGAGAAEGSIDASNMLKPALSRGEIQ
                     CIGATTLDEYRKHIEKDGALKRRFQPIHVQPPSTDETVRIIQGLRDRYEEHHGVEITE
                     DAIVEAVKLADRYITDRFLPDKAIDLIDETGSRAKLQTYALPTELKALEQELKKISRE
                     KELAISMQNFEEAVRHREEEERLRKLLDESKREWKKNQEKHKPTIGKEEVAYVVSKMT
                     GIPLFKLEEEESNKLLRMEEFLHKRVIGQNEAISAVARAIRRSRAGLKEAKKPIGSFI
                     FLGPTGVGKTELARTLAEFLFNSEDALIRIDMSEYQEKFTSSRLFGAPPGYVGYEEGG
                     QLTEKVRRRPYSVVLFDEIEKAHPDVFNVLLQVLDDGVLTDSLGRKVDFKNTVVIMTS
                     NIGTKLIQKGVSLGFQNDEKSGQALRKKDEVMGELRRSFSPEFLNRIDEIVVFHSLEK
                     EHLIHILDILLHELNLRLSDKSVNIEVDDEVKQWLIKEGYEPLYGARPMRRIIQRAIG
                     DPLSEELIKGRFKDNRKIKVVLRDGAPAFIEQEAMAGV"
BASE COUNT         3527 a         5595 c         5943 g         4246 t
ORIGIN      
        1 gcccgccgtt ccagcggatt gtcgcccggc ctgtttgatt cccgttggtg gtcgcaggcg
       61 gcgatcaacc tggccatgaa agatcccgct ttcaaggcgc agctgtttcg cttcatcgat
      121 gtgttgccgt cgctccgcga tgatgcccag gtggtccgtc tggcggaaga atattttggc
      181 gacatgagcg ggcatctctt cggcgcgcag tggggactca aggcactcgc gtccacgaag
      241 ctgggtgcgg cgctcagcgg gaaggccatc cgtcaccagg tggaacagat ggcgaccagc
      301 ttcattgccg gcgcgtccat cgagcaggcg gtgccggcgc tccgaaaatt atgggacgat
      361 gggcgggcgt tttctgtaga tctgctgggc gaagcgagtg tgaacgaacg ggaggcggat
      421 gcctatcggg atcgctgtct ggcagccctg cggatcctcg gtgatgtctg cccggcctgg
      481 tccccctcgc cgttgctcga gcacgatcac ctcggcccgc ttccccgtgt ccagttgtcg
      541 atcaagattt cggccctcta ctcacaactc gatccgatcg atcccgagag cagctatcgt
      601 gcggtggcgg cccgcctgcg tccgttgctg aatgtcgcgg gcacgctccc cgcctccatc
      661 atttttgata tggaacaggc ggaaacgaag gacctaattc tttccatctt catgcgtctc
      721 ttcgaggaag aaccgtaccg caccttcgcc cacgcgggga tcgcgctgca ggcgtaccgt
      781 atcgatacct atgacgatgt gcagcggtta ctggcatgga ccacacgccg gcaggtgccg
      841 atcacgatcc gcctggtgaa gggtgcctac tgggattccg acgccatccg gtatcgtcag
      901 cgtggttggc cgatgccgtt gttcgaacag aagtcccaga ctgacgtgaa ttatgaatcg
      961 ctggttcgtc tgttgctgga acaatcgcat ctgatcaggc cggccttcgg cacgcacaat
     1021 ctccgcagcc tggccgtgat cgaagcggtc gcggaggcgc tgggcctgcc accggtcgct
     1081 tgggaatatc agatgatctt cggaatggcg gaaccgttcc agcatgcgat gagtgatcgc
     1141 gggcggcgcc tccggctata tacgccggtc ggcgaactgt tgccgggcat ggcctatctc
     1201 gtccgccgct tgttagagaa cacgtcgaac gaatccttcc tgcggaaaga gtacgtcgag
     1261 tcgcagccgc tgtcgttgtt gttatcgccg cctgatggcg ccccgtctca cccggcctat
     1321 tcatcgccgg tggagcacaa gtcttccccc tatacatcac cgaccgaatt tgtgaatgaa
     1381 ccggttgccg atttttcgcg agcgtcggcg cgtacggcga tggccgatgc gatcgaacgg
     1441 cgccgcaaac acttggggca acgtctcgac ctgtcaacgc tggcggcgca tcttccgacc
     1501 gggccagacc tatcgacacg caatcccagt caccccgagc agatcgtggc ggtggtgcaa
     1561 agttatcagc ccgccgatgt cgcggcgctg acaaagattg ccggggctgc tgaggagtcc
     1621 tggacgagac ggccggttgc tgatcgtgtc gcggtgatcc ggaaggcggc ctcactgatg
     1681 cgggatcaac gatgggacct ggcggcctgg gaggtgttcg aagaaggcaa gccctggcgg
     1741 gaggccgatg cggatgttgc ggaggcgatc gattttctgg agtattacgc tggcgaaatg
     1801 gcacggctcg atcccccgcc tcgtttgggc cggtatcccg gtgagctcaa cgaggtgttg
     1861 tggaactcgc gcggcgtcac ggtggtcatc gcgccgtgga attttcccct ggcgatcccg
     1921 accggcatgg tggcggcggc gttggttgca ggcaacccag tcctgttcaa gccgtctgag
     1981 cgctcctcgg ccatggggta ccagctggcg cgtattctat tggatgccgg ggtgccgaag
     2041 gggctgttgc aatacattcc gggaggaccg gagctcggcc gtgaattggt ggtctcggca
     2101 gcggtaagaa cgattgcctt tacgggatcg aaggacgtgg ggttgggcat catgcaggcc
     2161 gcgggagttc agcaaccggg acaacggttc gtgaagcggg tcatcgccga gatgggcggg
     2221 aaaaacgcgg tcatcgttga tgagacggcg gatctcgatg aggccgtgac aggcgtggtg
     2281 caatcgttta gcggatatgc tggacagaaa tgttcggcct gttcgcgcgt gattgtcgtc
     2341 gactcgattc acgatgcgtt tctcgaacgc ctcgccgatg cggtgatgag tctccgtgtc
     2401 ggtccggcag atgatcccgc aacccaagtg ggcccggtga tcgatgcgcg cgcgaaacaa
     2461 cgcattctgg actatctcga aatcgggcgg cgtgaaggtc gggtgctggt ggatcggtcg
     2521 gcggaaggcc ccggatattc ggtcgggccg gtagtgatcg cggatatcga accggtgcac
     2581 cggttggcgc aggaagaaat tttcggtccg atcctggccg tgatgcgcgt cgcctcgttc
     2641 gagcaggcat tggaatacgc caatggcacg gcctacgcgc tgaccggcgg cctctattcg
     2701 cggagtcccc ggcacatcgc gcgtgcccgg gaggcgttcg atgtcgggaa tctgtacatc
     2761 aaccgcccga ttaccggcgc cttggtcagc cgacagccat tcggcgggca ccggttatcg
     2821 ggcgtaggcg cgaaggccgg aggcgaagag tacctgaaac aatttctggt tgctcgtgtc
     2881 gtcagcgagc aaaccctccg gcgcggattc gtgccgaccc tgtagccccg gcgccgactt
     2941 cacgctgacc tcttccagct cttccgtgat gtcggtgatg tttccgcggt catccttcag
     3001 cgcggccaat tcctggcgtt cgatatactt gaccagtccc acgcctttgg cgaaccaggc
     3061 cgtcattaca tccgtgccga ccgccgtccg atccacagag gacagtctga tcttcagggt
     3121 catcttcgct tccacgcgca cggcatcagg ataggtgccg gctggcacgg tgatcgattc
     3181 ctggcccaac accgttgaga gtccctcgac gtcgactttt tcgttggtgc cgtccccgtc
     3241 gatatcgctg ccaaaatcga tgtcggtccg attgaactgc tgaaacgatt gcgccacttt
     3301 catcggaaag cggatgatct ggtagggcgt caactgcttc tccagcggcg tgcccggttc
     3361 ggatccatag tagaccacgc cggcggcatc gcgccggtag aagctgtcgg agggaccgtg
     3421 gttaccggga ttggtgtcat ggaacacggt gacgaccagg ccgcccttca gggtacgcgt
     3481 gccggtgacc gaggagacgt tgctgaaata cttattctcg atcgtttgca gcggcccttc
     3541 agaaatctgg ccacgatatt gccagcgcgt gccgatggtg tcgggaaaat agtctgcgga
     3601 ttgggcgatg gcctgccctg cttcggtggc ggaggccgta tcgtgcccca cgaggatggc
     3661 cgcggatcca agaatgccta ctgcaatcag ggttgagcga aacaggttct gaaccattcc
     3721 ggctgtcctc caagtcaaaa aatcacggta ccataccagg acttccgcgg caagctggct
     3781 gctgccttgc cttcttcccg cgcggctcgc ataatcgctc gccgtgcaat cagaaccaca
     3841 gacatctgcg tcatctcctc gcgaactccg aaccgtcctg gttaccggag ggtccggtgg
     3901 tatcggccgc gctctttgcc tggcctttgc ccgcgccggc tattgggtcg gcgtgcacta
     3961 tggtcgccac aaagaagcag ccgaggaaac gttgcgcgag ctttccacag acggaggagc
     4021 gggcgccatc taccaggcgg atatacggtc aggtctggag attcaggcga tgatcgatgc
     4081 tgtgctggat cggcaagacc gcctcgacgt gctggtgtgc aacgccggcg tcgcgtccag
     4141 ccatctcgtg ctccgttgcc cggaagacga gtggttgcgc atcatcgata cgaatctcac
     4201 gggaacctat cggtgcctca cggctgtggc cccgctgatg atcaagcagg gtggcggatc
     4261 tatcatcgtg gtcgggtcct atgccggatt gcatggagcg agcggccaag ccgcctacgc
     4321 ggcttcgaaa gccgggcttg tcgggcttgt gcagacagct gcacgcgaat gggggccgca
     4381 caatgtccgc gtgaatctcg tctgcccggg gtggcaaccc accgcgctgg cgggtgatgc
     4441 ctttccttcc acggaacagc tgagtgatca tgtgctgggc cgtctgatga atctggagga
     4501 tgtgagccga accatttgtc acctcgcgca gcttccgggc atgtcgggac aaatcgtgaa
     4561 tctggatagc cggattctct actaatcgat cgtggagacg gaataggcat gatagggacg
     4621 acgggcgtgt ttgtgacagg taccgacacg ggtgtcggca aaacgctcgt ggctgcggcg
     4681 ctggtcaaca ggctcgtgcg gatgggccgt tcggtgggcg tcatgaaacc ggtcgaaacc
     4741 ggcgtggatg caggcttgtc ggatcgcacc gacgccgctc ggttgatggc ggctgcgcaa
     4801 gtgacggatt cgctcgacct cgtttcacct taccgtttcc ctgcgccggt ggctccctta
     4861 tccgccgctg ctgcccaagg gcgggtcatc gagctcgggg acatcgttgg acggtatgag
     4921 caactggctg cgcgttaccc atgcgtggtc gttgaaggag ccggcggcct cctcgtgccc
     4981 acgggcagtg attgggctat ggctgacctg atcagccgtc tccgtcttcc cgtcctgtta
     5041 gtcggacggg tcggtcttgg tggaatcaac cacgcgctgc tgacattgga agccctcgaa
     5101 cgccgaaaca ttccggtcgt tgcgttggtg ttgaatgaga cggtggcacc acgaggctcc
     5161 gttgaacagg agcaagcagc atcgacggta gcattgttac gggatcgagt ctcgatgccc
     5221 ttgatcggcc cgctccccta tcagactcgc gcagattgcg cctggcccga ggttgtagag
     5281 aatgtggccg gcagtcggcc gatcagtgac ttggccgagc ttgtgtggaa ggcggcggct
     5341 ggaagctccg gatagccgcc tcaagatcct gggccttgag aatggccgag atcaccgcta
     5401 ccccgtctgc ccctgccgcc gtgaggtccg tcacatgctg agacgtaatc ccgccgatgg
     5461 cgaagatggg caaggtggtg agtgtgcgtg ctgcgcgtaa tccttcaagg cctacgaccg
     5521 ggtcatgatc ggtcttggtg gtcgtcccga agatcggccc aaagccgatg tagtccggct
     5581 gaagagcgac cgcttctctg acctgtttcg cattatgcgt tgagagcccg atgatggcct
     5641 ccggccccag gatctgacgt gcgtcggcta gcgggagatc atcctgccct aggtgaacgc
     5701 catctgcctt gaccgccaat gccagatcgc accggtcatt gatgatcagt gtcgccccca
     5761 cttccgtcgc cacctgacgg agagcaagtg cctgccgata ggcgtctttc atcgaagcct
     5821 gtttgtcccg atattgaaac aggcgtattc ccgatgccgc ggccacgcgc agtacgtccg
     5881 tgagcggccg ttcaggcctg acggtgggat caaggataag atacagtccc ttgaggcaca
     5941 gttgtcgagt ggactgagac gtggcgcgct ccctggtatc gtaggctggt tacgcggatt
     6001 ggccggcgag aaagcggtcg aggaacgtcg tggagacatg ccccttttga aaatccggat
     6061 cgttgaaaat cttcctatgg agcgggatcg tggtcttgat tccttcaatc acgaactcgt
     6121 ccagcgcccg gcgcatacgg gccatcgctt cctggcggtc gcgtccgtgg gtaatcaact
     6181 tcgcgatgag ggagtcgtaa tacggcacca ccaccgcgtt cggttccatg gctgagtcga
     6241 cgcggatgcc caagccaccg ggagctgagt atttggtgat ctgtcccggg cacggggtga
     6301 acttctccgg gtcttcggca ttgatccggc attcgaagct atgcccgttc agcttgatgt
     6361 caggctgctt gaacgagagc ggcagtcccg aggcgatgcg gatctgttcc ttcaccagat
     6421 cgatcccggt caccatctcc gtgatcgggt gttcaacctg gatgcgtgtg ttgacttcca
     6481 tgaagaagaa gttccggtct ttgtcgagca gaaactccac cgtgcccaca ttgcagtagc
     6541 ggatggcttt gacggcttcg actgccgtcc ggccgatttc gcgtcgcaac cgttcgtcga
     6601 tggccggtga cggcgtttct tcgacgagtt tctggtggcg ccgttggatt gagcaatcac
     6661 gctcgccgag atggacgaca tggccgcggt tgtccgcgac gatctgcacc tcgatatgcc
     6721 ggggttccag aaagtaccgt tcgaggtaca cgccgtcgtg gccgaaggtg gacttggcct
     6781 ccgcctgggc cgcttgaaag gctctggtca attcttccgg cttgttcacc acccgcatgc
     6841 cgcggccgcc gcctccggct gaggccttga tgatcacagg gaagccgatg tttttggccg
     6901 cctcctgcgc atcctgctca ctccggagct cgcccgggct cccgggcgtg accgggaggc
     6961 ctttcttggc gaccacttcg cgtgctttgg acttgtcgcc catcaaggcg atgttttctg
     7021 acgtcgggcc gatgaatttt acgccgatgg actcgcagac ttcggcaaag tgcgcgttct
     7081 cggacagaaa tccataaccg ggatgaatgg cgtcggcacc ggtcacctcg gcggcgctca
     7141 ggacgttcgg aatgttgcga tagctgaggg cggcctcagg aggacccacg cagacatgtt
     7201 cgtccgccgc ccgtacgtgc aggcttgcgg catcagcctc ggaatgaatc gccacggttt
     7261 tgatgccgag ctccttacaa gcccggatga cccgaagggc gatctctccg cgattggcaa
     7321 ccaatacttt tttaaacacg agatactccg atgcgagtct tgctgtgcgt ctgcgtcatt
     7381 ctgcccttgt ccgtcgcgct cattcagccc tcacatcggc ccttgccggt cggcgtgagg
     7441 cggtcgcaga taagagacgt catgaggttg atgcgttcag gacgggtctc gtcacgaatc
     7501 cccatgacct ctgcggctag ggcgtggcgc tgggatctat caagaagagt ggctgtccat
     7561 attcgacggg tttggtgctt tccgccagaa ttttggtgat gcgcccgtcg gcctcggact
     7621 caatttcgtt catgagcttc atggcttcaa cgatgcacaa tacctgcccc ttcttcacgt
     7681 agtccccttc ttccacatac gggtctgcgt ctggcgaagg cgagcggtag aaggtgccga
     7741 cgatcggtga cgtaatagtc acctggccgt ctgtctctgc cgagggacga gcttgcgctg
     7801 cgggtgccgt gccggatgtc gccgattggg tgtggacggc ctccacggta tgcgtcgtcg
     7861 tggcgcgtac cgccggctca tgccgaatcc ggatgcgcat cccgctacgc tcgatttcca
     7921 gttcggtcag atggttgcgt ttcagcagat ccgccagttg ctgaatctgc gcggcctggt
     7981 cgggatttaa gatcatctgg tcggccgcag aggttcgtgg cgcaaaggcg ctcggcagca
     8041 caatgggctt agcggcagtc cggctttttc cggtcttctt acgtgatggg ctcaacgcac
     8101 gcgctccaca aattcacggg ttctggtgtc gatgcgaatg acttccccga tttccagata
     8161 cagcggcacc ttgattgtgg cgcctgtttc cacaatgacc ggtttgctgc ccccggaggc
     8221 cgtatcgccg cgcacgcccg gttcgccatc gacgactttc agttcgatga agttcggcag
     8281 cacgaccgta atcggcttgt gttcatagat caggatcttg gcgatcatgt tctctttgag
     8341 caggtcggcg ttgctgccga gctgactctt ttcgtaagtc gactgctcgt atgtctccgt
     8401 atccataaac gtataggaat cgttcgtggc atagaggaac tgcatatcgc actcttcaat
     8461 ctcgggggtg tcgaattttt cgccggaacg gaaggtccgg tcgaggacat tgcccgagag
     8521 atagcttttc agcttcgtcc ggacgaaagc tccacccttg ccgggtttca cgtgttggaa
     8581 ttccacaata taaaagggtt gtccctctac cattaacggg ctgccgttcc gaaactctgc
     8641 ggtcgaaatc acaacaactc tccttagtgc aacaagttca acggcgcgag gccgcgggtt
     8701 tctttctcac gtctgctcgg gtgcgtgacg atgagcgttt ggcacccaga tgtacggtca
     8761 atgcctccag cgccagcagg tatccggtcg ggccgaaacc ggcgatttgt ccgatggcaa
     8821 cgccggcaat gaaggaatga tggcgaaact cctcccgttg atggatgttc gagaggtgga
     8881 cttccaccgt cggcagggcg acggcggcaa tcgcatcacg gatcgcaatg ctggtatgcg
     8941 tgtatgcggc cggattgatg atgattccgt cgaaatgtcc cctggcattc tggatccagg
     9001 tgaccaactc cccctcacta ttggactgct tggtctgcac cgcaatcccg agttcaccgc
     9061 tccggcgggt aatggactta tcgatgtcgg ataatgacat ctgcccatac acggagggtt
     9121 ccctcgtccc caggagattg agattgggac catgaagcac aagtagccgc agcatctgtc
     9181 ggtcgcgcgc cccggttgtc agtaggctgc aatggatagg gatgccagca gcggcggcat
     9241 tctaacaggc tgtcaggggt gggtcaaacg ctgaaagagt cccggtgagt gtgtcagtca
     9301 ccgggctgcg gggtggcgtt tagcctggat ggtgctgagc caggcttcga ggcgcgcgat
     9361 tgcggctgca tgttgaacag cgggagatgg ggggctctgg ggaggcgtcg gatcgggcat
     9421 cgacacggta ggcgccgcgg actctgatac aaggacaacc ggagccggcg caggtgggac
     9481 cgctgccgtg atcttttcca ccggtgcttc cgcgaggctg cgcttcttct cgcgtttcga
     9541 tggcggcggc tcgtccggcg cgccggtgac actgcgtttg actgccaacg cctcctcatc
     9601 gaagggattg gcgttgagga tggctgtaca ggaacggagt gccaagtcgg cctgtccctc
     9661 cgcatgatag agcttggcga gaatgcggtg tgcccgaaga ttgtcggggc gttgtttcac
     9721 gacctcctcg agaatgacct tggctttttc cgcttgtccc agttgatcgt agaccctgcc
     9781 caaggccgcc atggcggtca cgaatcctgg atagaccttc aggccatctt cgagcacggc
     9841 cgcggcttcc tgccacatgc ccgccttgat gtattcatct gccagcggca ggaagtcttt
     9901 cgatcgtgga tccttcgcca cggctgtggc cagtcgatcg atctctgcgg cgatggcggg
     9961 aggaatgcgc agtggtgacg acacaggtaa ctccttgcga tgcggctgcg accggttgct
    10021 ctcgagttac cggcctgtat ggactgtcag gattcgatcc agtatccggt ccgcgacgtc
    10081 gcgcttggat aacagcggga gttcctcggg atcggcttca cgggccagca accagacccg
    10141 gttggtatcc gatccgaacc ccgaccctgg cgcggtcacg tcattcgcga ccagcagatc
    10201 aaggccttta gcatgcagct tttctttggc gtgggcaagg agatcatcag tttctgcggc
    10261 aaatccgacc agcacctgac tcgtccggcg atcacgtaat tcgcaaagaa tatcgtcggt
    10321 cgcttcgaga tccagatgcg tgaccggacc gcgccgcttc ttgatcttgt gtgcggatgg
    10381 ccgggcggga cgaaaatctg cgacagcggc agccatgatc accgtatcgc tccaatccaa
    10441 ttgggttgtc agcgccttat gcatctcttc agctgtgatc accggacagt attccacccc
    10501 ggctggtacg gggatcgagg tagggcctga gacgagcacg acgtccgcgc cacgagccct
    10561 ggcggcttcg gccagggcgt atcccatttt tcctgatgac cggttggaga gaaatcgtac
    10621 gggatcgatg gcctcctggg tcgggccggc tgagatgagc accttgcggc cggaccagtc
    10681 tcggcgcgga tgaacggcgt ggtgaaccgc tgccaggatt cgttcctcat cggctaacct
    10741 gccctgcccc tgtcggccgg atgccagcgg accatcctcg ggttccacga tgatggctcc
    10801 gcgtgcgcgc aaggtcgcga catgctccac gacggtggga tgctgccaca tgtccccgtc
    10861 catagccggc gcgaaaatca ccggacattg agttgtgagg agcatggtgg acaggaggtc
    10921 gtcggcgagt ccgagggcgg ctttggcaag gcaattggcg gtggccggcg caatgacgat
    10981 ggcctgcgcc tgttccggga gagacaggtg aagcatctcc tggtgcgctt cgaagaggtc
    11041 ggtcgccaca tgtgtgccgg acaatacttc aaatgtcagc ggggtgacga accggcaggc
    11101 gccggccgtc atcaccacgt tgactgtcgc ggcttcgcgc cggagcaggc gcaacagact
    11161 gaccgcttta taggcagcaa tgctccccgt gacggcgagc acaagacgga caccggaaag
    11221 tgaagggccg gtggtgtgca cgaagggaca ctactcctcg gcctccgggg cggcgaccgg
    11281 cttggcggta tcgtcaacgt agacgctgag ttccttcttg atctccttgg cgtcttctcc
    11341 ggtcatcatg gctaggcgtt cagtctcgcc ttccttcacg cgcttggatt ccttgatcgc
    11401 atcgcgggct tctttgccga ccaaaaactt cacgttgtgc cgcaacacct catccagtgc
    11461 gatactggtt tctttcgtga acttggagga tgcggtcgtg cgggcccctt ggaccaattg
    11521 cttggcgcgt tgagccgcga cgatcaccag ccggtggcgc gagtcgaatt cgccggtggc
    11581 atattccggt aacaacgata acatttcacc catgatgcat gtgctccttt gatgcggggg
    11641 cggaggagga attcccctgc ttgccctctt tgtcgagaat aaacttttct tccagccagg
    11701 tcatgttcag gcgtttggtc ttgatgcgtt ccgccagaaa gatgctttcc agttccttga
    11761 gcgattgttt caagtcgtca ttgcggacga tgtagtaata ctcgcggtag ctccagactt
    11821 cttctttggc cttctgcagg cgccgttgaa tttcttccgg cgagtctccg gcccggtttt
    11881 ggagcctggt gcgtaacgta tcgaacgagg gcggcaggat gaaaatgtac acgccgtctt
    11941 caaacttctt cttcaccgaa cgggcacctt gcacatcgat ttcgagcagg acgtcgatgc
    12001 cctgctccat tttttccgtc agctctttgc gaggcgttcc gtagagattt ccgtagacat
    12061 gggcccattc cacgaactcg ttccgatcga tcatctgccg gaacgacgct tcgtccagga
    12121 aatggtaatc ctgcccatcg atttcacccg gcctcggctt acgggtcgtg taggaaacgg
    12181 aatgccacaa tcccggcaca ttggccgtga tctgtttgca cagcgtcgtt ttcccgcttc
    12241 ctgacggggc ggaaatgatg aagagaatgc cccgccgtac ttgagccggt ttgtcgtgag
    12301 atggaacggg cgcagtgctc atagatgatt caatgccggc gctgcgccga cgttactcca
    12361 cattttgaac ttgttcgcgc aatttttcca gttcggcttt catgcggacg accagcgcgg
    12421 caatctccgc atcgttggct ttcgagccga tggtgttcac ttcgcgtccc atttcctgca
    12481 ggagaaattc cagcgttttc cccacggact cctggctacg gagctgctgg tcgaactgta
    12541 ccatatgtga ctcaagtctg accaattctt ccgagatgtc cgaccgatcg gcatacaccg
    12601 ccagttcctg ctggagacgg gccggatccg ggacttcgct ttggagaagc gtctcgatcc
    12661 gcgctttcat gcgatcaaag gcgattttcg cgagatccgg cgccttcttt gccacgatgg
    12721 actgtgcctc ccggattgcg tccaggtgaa gggtcaggtc tttcgtcagc gcctcacctt
    12781 cccgcttgcg catcttctcc agctcggtca gggctccgcc gaggacgcgc aacagggtct
    12841 tgccaagatg gtcggtatcc accggttcat cggtaaggga gacgatgtcg cgaaaccccg
    12901 cgaccatgga cagatccacc ccgccccgca atccgagcgt cttctgcagc tttttgaggg
    12961 ccgtatggta ctgcttggcc agtacctgat cgatgtggac ggttttcagg ctgccccccg
    13021 cggtctggac tgacacggag acatcgactc ttccgcggag gcagcgttgt tgaacggcct
    13081 tgcgaatggg atcttccaac tgcgccaggg atcgaggaac cctgaccgcc acttccagaa
    13141 accggtggtt gaccgagcga atctcgacgg tgacggtggc ctgttgcgac gtgccatcct
    13201 ttttcccata tccggtcata cttcggatca tcgtgtgagt ttcccttccc aatgacaatc
    13261 ggtgtagatg gcgcagtttc cgcatttcgg ggtgcgagcc aggcagacgt atcgcccatg
    13321 cagaaggaga cgctgcgatc cttccgtcca ttccgctgcg ggcagcaact gctggaggtc
    13381 catttcgact ttttcgggat ctgtatggcg agtgaggtgc aaccgccccg ccactcgttt
    13441 cacgtgagta tcgaccacga tcgccggctt atcgaacgca ttccccagca gaacgttcgc
    13501 ggttttacgc ccgactccgg ggagtcccgt gagcgcttcc atggtttccg gaacctggcc
    13561 atgaaatatt tcgaccacgg cttttgcaca gtggatgagg ttcttggcct tcgtcttaaa
    13621 aaatcccgtc ggccgaatca gcgcttctaa ctccgcagcg tcagcagcgg catagtcttg
    13681 cggacgtcga taccggcgaa agagcgccgg ggtgacctgg ttcacgcgct ggtcggtgca
    13741 ttgagccgag agaatagtgg cgaccagcaa ctcccacggt gtgcgatagt ccaactcgac
    13801 tttccgggca ggctcggtgg cccgtaacgc gcggagcatt cgcgccaagc ggcgtttgtc
    13861 gggctgagcg gacacgtgat gtgcggtggc agctttcatg atgcgcgggt tgtggcggcc
    13921 aattgtgcag tggtcacgag tgagatgcaa gggcccgctc ttgcggtggc agctcggtat
    13981 ctgcctcgtg cgaagggggg ctgggaacgg ccggcaacaa tgcttcgagg tgtgcgatca
    14041 aaggccggag cgtttcccgg tccagtgccg agatagcaat ggcatgatac cgttggctga
    14101 ggacatcagc ctcacgcggt gagagtcgat cacatttgtt taacaccatg acgcgtggaa
    14161 tcgtgtccaa ttggagcgat tgcagcacgg catcaactgc cgcaatctgc tggtcgagat
    14221 tcgatgcgga ggcatcgagg acgtggagta gcatgtcggc atcgcgcagc tcatccaatg
    14281 tggtgcggaa ggcgccgacc agatctttgg gaagatcccg gataaacccc accgtatcgg
    14341 tcacaatgac ttcgcgatca tgcggaaaac gcaggcggcg gctggtggta tccagcgttt
    14401 cgaacaggcg gtcctgcgct gaaatctgac tctgggtcaa ggcgttgagc agggtcgatt
    14461 tgccggcgtt cgtatacccg acgatggaga gaatcgggag cccctgccgg acacgtctcg
    14521 cgcgccgctg atcctgatgg cgagccacgt ggtcgatctc gcgctcgaga tgggcgatac
    14581 ggtcgcggat gcgccggcga tcggtttcca gtttggtttc gccgggaccg cgtgtgccga
    14641 ttccgccgcc gagccgtgac aatgaggtac catgccctga gagccgcggc aacaggtacc
    14701 ggagctgggc caactcgact tgcactttgc cttctcgcgt gtgcgcgcgc cgggcaaaaa
    14761 tatccagaat gagctgggtg cgatcgatga ctttcaggtc ggtcacttcg gagatcgctc
    14821 tggcctgtgc cggcgccagg tcctgatcga agatgatgag gtcggcgccc ttctgcagcg
    14881 accgcatgac gacgtctttc aatttgccct tgccgagtaa ataccgctca tacccctcat
    14941 gggtgcgttg cgcaatacga tccaggactc gtacgccggc tgattcagcg agttccgtca
    15001 actcttctaa atgctcgtct tgttcggcat ggcctttcgg cgcggcgctc accaaaatgg
    15061 ctgattcctg gcctccggtg acggtgtgct gcgtatccga tcgctggagg tcgctttcaa
    15121 gcgtatggag gaaggtatcc agttgcagtt ccagatcatg gaatggcacc ggcttcagga
    15181 gacggcacac ctcgccttgc tgattgggcg gaagcaggtg cgcgagatgc agcaagccgg
    15241 gttcgcccgt ctcggtcaca cccaacgctc cgatgagatc caatcgcagg agtgctaagt
    15301 gtgtgagatc atcctggctc agcggttcgt catgaagatg ggtgcggatc agtctgaggc
    15361 cacgcaatga atgtgatccg accctgaatt tggccagcga ctcgaacgtc ggtgcacagc
    15421 ctgcccccac caggacttgc tcaatggctc cacggcgcgt gatcaggagt ccaatgggcc
    15481 ggcgaatttc acgtgacagc tgggttgttg tacgagccaa ttcggcagtg aggactacag
    15541 aggcagggat gcggcggcga tacaatcgtt ccagcgcggc aaggtggctg gctttcaggc
    15601 cgctgacatg tccgtgaatc gtggcgatga cgggactcct tgcgatgaga acattaggag
    15661 gtgcgccgga cgaccccgct ccccgaccag gccggcagcg cacagtccgg catggcttcg
    15721 cagtcgaatg acgcgacatt cccctggaga agcgctcgtt gtcccgcagc ggcaatcatc
    15781 gccgcattgt cagtgcagta tgagagggcc ggcaggctta attcaatgcc ttccttgacg
    15841 gctcgctcgg ccaatcgggc tcgaagccgc gaatttgcgg agacaccgcc cacgacggca
    15901 agggcggaca cccctgcccg ctctacggcg gcgaaggcct ggcgaaccag gacatccacg
    15961 attgcctcct ggtaggccgc agccaggtcg gtctgttgct cggcaatggc ctccaggctc
    16021 atgccttgta aatgataaag cagcgcggtt ttgagtccgc tgaaactaaa atcgaactga
    16081 ccggttctca cgcgagagcg cggaaatcgc acggctgtgg gacggccttt ccgcgccgcg
    16141 gcatcgatga gcggtccgcc ggggtacccg agacccagca tctgcgcccc cttatcaaag
    16201 gcctcgcctg ccgcatcatc gatggtccgt cccatgagat gaaatccacc cttctcttcc
    16261 gcgtggaaca gatgcgtatg tccccccgac gcaatgagga ctacgcagtc tcttggaaat
    16321 gccggacgat tgatccaggc cgacgcaata tgcccctcga ggtgactgac gccgaccagc
    16381 ggaatatcca aggcataggc tgtggacttc gcataactga ggccgaccag aagggcgcct
    16441 gccagccctg gcccctgagt gacggcaatg gcccgcagat cgcgccatcc gagaccggct
    16501 tcctcgagtg cccggcctgt cacctggtcg atgttctgga tatgagctcg cgaggcgagt
    16561 tccggcacca ctccgccgaa tcgctcatgc acggcttgtt gagatgaaat aatgttggaa
    16621 aggacgtgtc cctctccatc gagaacggcg gcggcagttt cgtcacagga ggtttcgatg
    16681 ccgagaatgg gaccgaggat tgttgccgaa gctgcgtgag tcatagggca gattgatacc
    16741 gccgcgttgg aagagctgac cgttcgtttg cttcagagga ccgcgccagg gggtgtggac
    16801 acgtggctgt cacccttcgg gcgagagacg gtttggggtt ggatgaattc aacaattgtc
    16861 tccgccgtga aaagcgacaa cccccggatc cggttgggga ccgcgggggt tgccgggtag
    16921 cgtacaggat ctcaagtacc aatcgatcct atcgtgataa gcgcgtcgtg ttctacacgc
    16981 ccgccatggc ttcctgttca ataaaggccg gcgcgccgtc gcgcagaacg accttgatct
    17041 tccggttatc cttgaagcgg cccttgatga gctcctcgga caacgggtcg ccgatcgctc
    17101 gctgaatgat gcggcgcatg gggcgcgcac cgtacagcgg ttcataccct tccttgatca
    17161 gccactgttt gacttcgtcg tccacctcga tgttgacgct cttgtcgctg aggcggagat
    17221 tcagctcgtg cagcagaata tccaggatat ggatgaggtg ttccttctcg agcgagtgga
    17281 aaaccacgat ctcgtcgata cgattcagga attccgggct gaaggatcgg cggagctcgc
    17341 ccatcacttc atccttcttg cgtaacgcct gaccgctctt ttcgtcgttc tggaaaccga
    17401 gcgagacgcc cttttgaatc aacttcgtac cgatgttgga cgtcatgatg acgaccgtgt
    17461 tcttgaagtc gacttttctg cccaggctgt cggtgaggac gccgtcgtcc aacacctgca
    17521 acaggacgtt gaacacgtcc gggtgggctt tttcgatttc gtcgaacagc accacggaat
    17581 aagggcgccg acgaactttc tcggtcagct ggccgccttc ttcatatccg acataaccgg
    17641 gaggggctcc gaagagccgc gaactggtga atttctcctg gtattcggac atatcgatcc
    17701 ggatgagcgc atcttcacta ttgaagagga actccgccag ggttcgcgcc agttcggttt
    17761 ttccgacacc ggtcggtccg aggaagataa aggagccgat aggcttcttc gcttccttga
    17821 gtccggcccg ggatcggcga atggctcgtg cgaccgccga gatggcttcg ttctgcccga
    17881 tgacccgctt gtggaggaat tcttccatac ggagcagttt gttggattct tcctcttcca
    17941 gcttgaagag cggaatgccg gtcattttgg acacgacata ggcgacttct tccttgccga
    18001 tggtcggttt gtgcttttcc tggttctttt tccattcgcg cttggattcg tcgagcagtt
    18061 tccgcaggcg ctcttcttct tcccgatgac gaaccgcttc ctcgaaattc tgcatcgaga
    18121 tagccagttc cttttcacgc gagatcttct tgagctcctg ttccagcgct ttgagttcag
    18181 tcggaagcgc gtaggtttgc aatttggcgc gagagccggt ttcatcgatc agatcgatgg
    18241 ccttgtctgg caagaatcgg tcagtgatat accggtctgc caacttgacg gcttccacga
    18301 tcgcgtcctc ggtgatctcg acgccatgat gttcttcgta ccgatcgcgc aaaccctgaa
    18361 tgatgcggac cgtttcatcc gtgctcggcg gttgcacatg aataggttgg aagcggcgct
    18421 tgagggcccc gtccttctca atgtgtttgc gatattcgtc cagcgtcgtg gcgccgatgc
    18481 actgaatttc accgcgcgac agagccggct tgagcatgtt ggaggcgtcg atcgagcctt
    18541 cagcagcacc tgcgccgacc agcgtgtgca attcatcaat gaaaataatg atattgcccg
    18601 cctgcacgat ctccttcatc accactttca accgctcttc aaattggccg cggtatttcg
    18661 tgccggcgac gagcgagcct aaatcaagag caataacgcg acgggacagg agattgtcgg
    18721 gaacctcgga ggcaatgata cgctgcgcga gtccctcgac gatggctgtc ttgccgacgc
    18781 cggattcgcc gatcagcacg ggattattct tggagcggcg gctgaggatc tgcagcaccc
    18841 gctcgatctc atctgcgcgt ccgatgacag gatccaattg accctcttgg gccaattggg
    18901 tgagatcgcg tccgaattcg tccagtgccg gggtgttgct cttacggtct ctctcgcgag
    18961 gagcagactt tcgcaggaag gtcaccgtga gctgccgggc agtcaggagg ttggcgccaa
    19021 gacttctcag aatctttccg ccgatgcctt cctcttcacg caggaggccg agcaacagat
    19081 gctcgctgcc gatatggtta tgaccgagta accgggcttc ttccaccccg tactcgatga
    19141 ctttcttgac ccgcgggctg aaaggaattt ccccgaaggt catcgtcgtg ccgccgcccg
    19201 gcaggttgcg ctcgatttcg aggcgaatct gttcggtcga gaggcccatt tttttcagga
    19261 tcatcagcgc aatcccatcc gtctcgcgaa ggatggccaa caccaggtgc t
//
LOCUS       DAOQPD010000077        19298 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1420_length_19298_cov_24.387466, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000077 DAOQPD010000000
VERSION     DAOQPD010000077.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 19298)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 19298)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19298
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1420_length_19298_cov_24.387466"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(257..1582)
                     /locus_tag="PK063_14985"
     CDS             complement(257..1582)
                     /locus_tag="PK063_14985"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF005589.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-[acyl-carrier-protein] synthase
                     family protein"
                     /protein_id="HMZ98403.1"
                     /translation="MTPQTSRRVVITGMGVISPLGSTVDLFWHLLSQGESAVRPITSF
                     DTSPFQACLGAEVRDFDPEDFLHRKQARRMGRATQFAVASAMMAARDSGIDLEQEDRG
                     SIGISIGTSIGGMKEAFEFHDAAKVTAYERVNPFTMGMTFPNAISSEVAIVLGLHGPC
                     ETYSIGCSSTANAIGRAYEWIKSGQASLVVAGGTEAPLHPSVYAAMNAGRALAPDERG
                     TIRNLPRPFDKTRCGMVLGEGAGCFILEEYEHARARGARMYAELEGWGFTCDAHSMVK
                     AATTGQEQQRAARLALSTAHWFPEEVDYVNACGLGTMELDALETHTVKQVLGTHAYRV
                     PISSFKAALGHAFAASGAFQLIGTAKAMEHQFIPPTLNLTNPDPTCDLDYVSGEGRAA
                     HIDRALINSFGFGGKNIVLALSRIDTRVATNSPVAASAGYGLHHLAGVS"
     gene            complement(1624..2895)
                     /locus_tag="PK063_14990"
     CDS             complement(1624..2895)
                     /locus_tag="PK063_14990"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98404.1"
                     /translation="MKQLAAHPAAMDATFTLLDLLQQRKTRRFGRGMTLPGGPLQYTS
                     HHDPVPLSREEERYLIYAAIGRSGRNLGDMQFVGRPGVSVGQGNALMNFNSRTVPSPC
                     SAQTTQLFYTNDDGVFFVADAAGPDHPWDLNVIQLQSSRLDIPREAPFMLPFNQWYTN
                     RPGTTLFMPVTNIASLYLNLLLMMFSEETGYFIVDTDNGNAACGLEAFRKSAGGHLHD
                     DMKARRMFSLRELDAAICETAIQEQGIICEHLSLMQQALGLGGGIQSVGSGRHLLGME
                     PHIYPGLGFHFVVPPGKPLRANPVGIPGVWEGPTPPFVPSMKDAVTNLVESKFGADGT
                     FRKPQEQPYVQRNTAQQVPQHSERAIEATIAFTEYVLATYGRFPAHADACKSIVACQT
                     HHLDEDFYATFYPDSALPDAHREHMHTWHSH"
     gene            complement(3126..3923)
                     /locus_tag="PK063_14995"
     CDS             complement(3126..3923)
                     /locus_tag="PK063_14995"
                     /inference="COORDINATES: protein motif:HMM:NF015437.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="HMZ98405.1"
                     /translation="MSQPAFSAKEFQRLGEIMYDARSVNRNDGVWQLVSAVQRVVPYE
                     FSGCGAVDLLHGIDPSLGHSTYPREFCQLYMGQGLAADPAVNRLLTSGQTVTSSADEP
                     VGNEPRDVTSLKLDFGIKTCLSAGVRGDHGACSYFAFSNFDAKQADKLRLLLDILTPH
                     FHLSYMRCKSAWTPNRQAQPALLLSKREEEILRWVAAGKTNWEISVILKVSLNTVKFH
                     LKNIFQKIGVENRWSAIAYWQNGEQHRIIPPSAPSDDRSPSDPNRPT"
     gene            complement(4172..5149)
                     /locus_tag="PK063_15000"
     CDS             complement(4172..5149)
                     /locus_tag="PK063_15000"
                     /inference="COORDINATES: protein motif:HMM:NF013354.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98406.1"
                     /translation="MRRFAGALLLCCAAAVPNLGFAESSSEHLDWGRWSFDYEVKDNT
                     GLAIRNVAYDGELVLGKASMPVLRVKYVKERVWWNPFTWFGSRADSGRCGPFQDRLRW
                     VDLVPIVNCGDNKVCVESATSHGVKWLELGIYARIGEYHIYQSWHFSEDGELRPVIQS
                     RGLSCNTDHIHHPYWRFDFDVNGNGMDQVFVRDNGGPDKGWGPGWTKYTNERNDVKHA
                     STQRTWFVRDQPTGHGVWLLPGDGYAPLKDDGERDSFADHDVAIRRAKPDEDVPWVFG
                     ARGQLGYDEDNQGVQEQDVVVWYVAHLPHMAALGPTKWLTLGPTLKIQR"
     gene            complement(5168..5953)
                     /locus_tag="PK063_15005"
     CDS             complement(5168..5953)
                     /locus_tag="PK063_15005"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98407.1"
                     /translation="MATRFIMLNSAAIMLLLLAAGCSLDAASRGPFGPEDPETAIPKK
                     PLPAQVPTKHVLEFTADESPGHIKPKMAGSTNEAAVTRSPNPTASLSTSEIAGLRKTA
                     EADSRVRSLLGERWGFVDADPMPPTSKITFGCCRQQARFTKLTYFSYSHNVAVQVQLK
                     DGTVLQASRIDGYLPPEGPQDVQRGIELARADARLAGKVNGLQGHGLLMQPDRGFFKN
                     DPGYGHRVIWITFSQGVGGDPKYWAQVDLTDDRVLDAGDEPPR"
     gene            complement(5958..6479)
                     /locus_tag="PK063_15010"
     CDS             complement(5958..6479)
                     /locus_tag="PK063_15010"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98408.1"
                     /translation="MNRSIDGVITFLRDNDNVIKQLMETAESATNDIEQLSTSVDHAR
                     EEAQVLVDQLGAVEFSVGRDDDTKVRQTALLEAVAALRKKFELYKNDPLRRGIYAAEI
                     SNLYLQLANTFNNETVAKIVPFEADEIETYKDLMSKAVLDAASRKKRAAVIKAGVQIS
                     RLALGVAGKLALV"
     gene            complement(6491..7201)
                     /locus_tag="PK063_15015"
     CDS             complement(6491..7201)
                     /locus_tag="PK063_15015"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98409.1"
                     /translation="MVRRGMTLLSLAMLLLMATGCHSIHSRSVRDLIQMEGTKIDAAQ
                     TNIDLFQKETEERITFLEQARSSLHESFKSLQIQEAKHRFALASFRNLTNKRGEAAYA
                     AAYLTSLIYMTDVQGLEKAVWDQFEEDFCALRDTANALNDSWKHTATLHAEVQRFAKQ
                     SALASVDPEFVAAILDQAPGRSEQIMSVLNHSRTVNDALEEVVGARILRVGGLDRAQR
                     FTADLVELLDRLKKDDGQ"
     gene            complement(7237..7869)
                     /locus_tag="PK063_15020"
     CDS             complement(7237..7869)
                     /locus_tag="PK063_15020"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98410.1"
                     /translation="MRMLRIAGTLLFASLAACSTPPEIKQALAAKDQAYAENEQLMQQ
                     YRELVSNVTTRHLKWYRYVQTRLKLDLALQWATTNPRVADVPDAALAEDDAAALGPDV
                     LTLVNAMRLKSLPERKGPNGQPLFAAGSGDMSTLIQQLPDLIARVEQQVAAGAKIPQT
                     VDLTAFDRYRNNVEALRRINGLIKQYLDIDVTASRSDVQSLADALRTVHR"
     gene            complement(8117..9931)
                     /gene="uvrC"
                     /locus_tag="PK063_15025"
     CDS             complement(8117..9931)
                     /gene="uvrC"
                     /locus_tag="PK063_15025"
                     /inference="COORDINATES: protein motif:HMM:NF001824.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HMZ98411.1"
                     /translation="MAGSCETLQSKLDHLPEQPGCYLFRNAKREILYVGKAAVLADRV
                     RSYFQKGSDQTPKTSLLVSEVADLETIVTRSELEALILESNLIKRHRPRFNIVLRDDK
                     QYPYLRLPIKESFPRLSIVRRVQKDGALYYGPYTPAGALRETLKVIRKAFPLATCDID
                     IDGRADRACIEFEIKRCMAPCTGNQSREDYHVIVKQVRQFLEGRDRELLDSLRQDMES
                     AAEREEFEEAARLRDRLFSVERTLEKQRITQVTTTDQDVIGIARQGTAADLQLLFVRG
                     GLLIGRKDFFWPQSADSPDEELVRSAIEQFYNKEGQPPKELLVPTDLVDAPLIEQWLS
                     DKRGDTVRLLTPERGAKHQLVLLAEENAAAAIADHLRNEALDRQATAELKRLLRLDTV
                     PRRIEGFDISNIMGNQSVASLVVWEDGQAKKSDYRKFRIQTVEGANDFASMQEAVMRR
                     YGATEDLARPDLILIDGGLGQLSAALEGLKQVGQEQIPIMGLAKARGEKDERIFLPGR
                     KNPIVLRPTSPATHLVQRIRDEAHRFAITYHRNLRGKALLSSELDQIPGIGKIRRSRL
                     LKQFGSLPQIASATDEQLKSAGLDATTVAALRKTLIPS"
     gene            complement(10053..10922)
                     /gene="dapF"
                     /locus_tag="PK063_15030"
     CDS             complement(10053..10922)
                     /gene="dapF"
                     /locus_tag="PK063_15030"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014959965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HMZ98412.1"
                     /translation="MKNGFFRGHGLGNDYVVMDPKELSFNLTPGKIRGICDRHWGLGS
                     DGILALVPSKKADFGLRIYNPDGSEAEKSGNGLRIFARYLHATGKTKKRAFTVETKGG
                     LVSITLHVDRHGDAAAATVEMGRATFQPSALPCTLSVEELIQAPIEAAGRSLQFTGVS
                     VGNPHCVVFKEAGQSWTREELLTLGPALENHPLFPKRTNVQLAVPTGPKEIFILIWER
                     GAGETQASGSSSCAAASAAVKLGLVKGPVKVIMPGGTLNIEVAKDFSLTMKGPVAEVA
                     RGSLSPSFVRTLR"
     assembly_gap    10939..11038
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<11039..11979)
                     /locus_tag="PK063_15035"
     CDS             complement(<11039..11979)
                     /locus_tag="PK063_15035"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF013098.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HMZ98413.1"
                     /translation="MQPIDSRAQALIRDMREEDRDAVIAILTNSDPWKRLGFAASDWL
                     RIFAPLPAGRDTFILEVEGAVLGIAIVRRKFLFGDYLELLGIAPSATGRGFGSSLLSH
                     IESLTFARAQNLFACVSDFNEAARAFYRKQGYKEIGPMPNFLIPGYAEILLRKTAGPA
                     RKWRHTIETADGDHVPQTVNGVPLMKVTKLLHTRMRVSDIDQTIRFYQNVLGLEVMDR
                     KVSPRGSHLAFLKVPNSDELIELCSFPASGPVTVQEDLVHLAFEVENLDETIRSLESK
                     GVRITDGPTPTSSGSRFLFIDAPDGYEVELIERPPGTA"
     gene            complement(11946..12668)
                     /locus_tag="PK063_15040"
     CDS             complement(11946..12668)
                     /locus_tag="PK063_15040"
                     /inference="COORDINATES: protein motif:HMM:NF013672.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HMZ98414.1"
                     /translation="MRLKDCWIGIAAICGLVFITEARPSSAQVIKSGPASCPAVALTY
                     DLCPVRTASGFDRELIDYLIEHKVPTTFFMSGRWMIKHDAEVKQLLAVPFFEIGTHGD
                     VHAHLPMHDVEEQQQEIMGPVRLLKTKYGRPATLFRPPYGEYNDETVDAVKALGLRFI
                     LWNIESGDPDPALSADAILTRVQKRLKPGSVIVLHANGKGKHTREVTEALAGQLLPDK
                     GLAPMTISDLLRCNQSTVAPKP"
     gene            12740..13915
                     /locus_tag="PK063_15045"
     CDS             12740..13915
                     /locus_tag="PK063_15045"
                     /inference="COORDINATES: protein motif:HMM:NF014244.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HMZ98415.1"
                     /translation="MQGPDWKIGRMFGIPIHVHASWLFVFFFMTWSLATGYLPDTLPG
                     LSEPRYWAMGGVAALLLFASVLLHELGHSLVALRYRIPIGQITLFIFGGVAQMRKEPP
                     HPRAEFLIAIAGPLVSFILAGLSLVLVAVLELFPAESSLHGLMALGTLLGMVNTQLGL
                     FNLLPGFPLDGGRALRAGLWAWSKDYYRATSQAALVGLLFGVTFALFGALLLFGALSG
                     TASSALASSGGWIVLLGAFLFTAARGTRKQAAIRASLASVPVRELMVRNVVALSPDLS
                     LEEAVNQYFLPYGYGGFPVVHEDRLLGVVAVRDIQSVKNSLWAFRRVADIMQPASDDM
                     VVSPDLSAMQALEQMIAVGAERLVVVQDGQLLGLVTRASIGHFIEQHHPSGLGKSSS"
     gene            complement(13991..14842)
                     /locus_tag="PK063_15050"
     CDS             complement(13991..14842)
                     /locus_tag="PK063_15050"
                     /inference="COORDINATES: protein motif:HMM:TIGR00765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HMZ98416.1"
                     /translation="MTELTFLSNVFDTFRRRGCPSLAASLAFYSILSLFPMVFLLLYG
                     ISFIVSQDVIGYQFLLGFLKGFLPSMGERLAKDIRRVAEQEEVRWAVFLAFGWFSALV
                     FYELDYAMNTVFGTAAKRHPLISTLVAVALIWMLGFLTLISFVATQAIELLTTYAPRF
                     LGMNLVAIAAHDFLITYTLPFLLAFASVTCLYRFLPHQRPTWREATIGGAVFSLLWVS
                     AKVLFVTYLEDAAVYTQLYGSLLEVVLLLLWVYYSSALVLLGAVVTYECQCRRPALLD
                     ESATLPG"
     gene            complement(14978..16453)
                     /locus_tag="PK063_15055"
     CDS             complement(14978..16453)
                     /locus_tag="PK063_15055"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA];
                     GO_function: GO:0048038 - quinone binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH dehydrogenase (quinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit N"
                     /protein_id="HMZ98417.1"
                     /translation="MTFPLQDLLAILPELIVIGTACLILALDPILGADKKDVLAWLTL
                     GALAMCMGLTSSHLTGQTYAFSNLVVIDSYGAFWKLLLYIVTGLTVLLSLAYLKAERL
                     SIGEYYGFILLALVGMMVMVSGADLLTIYLGTELMSLSLYVMAGLKRTEARSLEASAK
                     YFVLGAFSSGVLLYGISLLFGLAGSTRLSVIAEAITTHGTANPMLSLALVLLAVGFGF
                     KLAVVPFHMWTPDVYQGAPTSVTAFMAVASKAASFGAFLRVFVEGLGGASADWSVLFT
                     IICLATLALGNLVAIVQTSIKRMLAYSSIAHAGYALIGVVVAARHSGEGTSSGFASVL
                     LYIAVYSFMTLGAFALVGMLRKEGQESENIEDYAGLAKREPLAAFFMLVFLVSLAGIP
                     PTAGFIGKFYIFMAAVNGGMTWLAVVAVIFAAISAFYYLRIVMVMYMREPEGAATAHS
                     RLETSPALSFVLACALAGVVFLGLFPNGLWSLATHAAPLLK"
     gene            complement(16450..18009)
                     /locus_tag="PK063_15060"
     CDS             complement(16450..18009)
                     /locus_tag="PK063_15060"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_process: GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit M"
                     /protein_id="HMZ98418.1"
                     /translation="MTSFPWLSLIVFFPLIGAVICFLVKAESSRWVALGFTVGNFLIS
                     LPLWWLFDSSTANMQFVERASWISSPPVNYSLGMDGISFPLVLMTTFLMPFCVTVSWT
                     AIEKRVQLFMSMLLVMEAAMVGVFVALDFVLFYVFWEVMLIPMYLLIGVWGGPNRLYA
                     AIKFFLYTLAGSLLLLVAILALYFQGGHTFDILELSRGTYGASLQMWLFLAFFAAFAV
                     KVPMFPFHTWLPDAHVEAPTAGSVILASVLLKMGTYGFLRFTLPMLPDATVAFTKPMI
                     ALSIVAIIYGAYMALAQSDIKKLIAYSSVSHMGFVTLGIFVLNIQGIEGAVMQMVNHG
                     ITTGGLFLCVGIIYERTHSRQILDNTGLAGPMPRYAMFLMIFALSSLGLPGTNSFVGE
                     FLVLAGTFVWSQFATAFAALGVILAAAYILWLMQRVVFGTPAPAHRAHLLDLNARETA
                     TLVPLIALVFVLGIFPNPLLTRMHASVTNLLNAQKAPAYATAPQQPALPQPAATMAAM
                     SSSSSEQAAAR"
     gene            complement(18084..>19298)
                     /locus_tag="PK063_15065"
     CDS             complement(18084..>19298)
                     /locus_tag="PK063_15065"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050136 - NADH dehydrogenase (quinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit L"
                     /protein_id="HMZ98419.1"
                     /translation="LLFTGAVGKSAQVPLHVWLPDAMEGPTPISALIHAATMVTAGVF
                     MVARLAPLYNLSPTAMTVVALVGALTMMLGATIALTQTDIKRVVAYSTMSQLGYMVMA
                     CGLGAYSAGMYHLLTHGAFKALLFLGCGSVIIALHHEQDMRHMGGLKDKLPVTYWTFL
                     VGSLALAGFPLTAGFFSKDDLLVSSWSAGPLGQVLTICGLVTAGLTAFYSFRLVFVTF
                     WGKSHVDPHHAGHVHEPSTTMTAPLMVLAVLSIVAGYLGIPAFLEPVFHGEGAGAHHE
                     GSAALGIMALATLMGLTGIGAAYYLYVLNPGLPDRLAQQWRAAYELSLHKWYIDEAYD
                     RSFVRPTLSAAQGLWKHVDVAIIDGAVNGVARAVAWGGWLIRLTQSGQTQHYALGMTL
                     GAVVILTVYLLL"
BASE COUNT         3951 a         5438 c         5863 g         3946 t
ORIGIN      
        1 gttgtttcgt tcatattcga ctctcaccta aatgtggatg gatgcctggt tgttcctgta
       61 tatgcctgcg cccagaaacc ggatgtcctg agggttgtga agaggcgctc ggccttcggt
      121 gtccaccctg cttactgtga ccgacgatga aactgacgtg gcatcgtgcg gcccggcctg
      181 aaacagaccg ggccgcatgg accgctgctg gtgtgatgcc cgtggtcatg agtctgcggt
      241 ccttcatgtc gtgagcctat gacactccgg ccaaatggtg caggccatat cctgccgatg
      301 cagccactgg gctgttcgtt gccaccctgg tatcgatgcg ggacagggcc agcacgatgt
      361 ttttgccacc gaatccaaaa ctattgatca gcgcacggtc gatatgtgcg gcccgccctt
      421 caccggacac ataatccaga tcgcaggtgg gatccggatt cgtcagattc aatgtcggcg
      481 gaatgaattg atgttccatc gccttggccg tcccgatgag ttggaaggcg ccgctggcgg
      541 caaaggcatg gcccagtgcc gctttaaatg aactgatggg cactcgatac gcgtgggtgc
      601 ccaagacctg cttcacggtg tgggtttcca gcgcatccaa ttccatggtg ccgagaccgc
      661 acgcgttgac atagtcgact tcctcaggga accagtgagc ggttgacagt gccagcctgg
      721 ccgctcgctg ctgttcctga cccgtggtgg ctgctttcac catcgaatgg gcatcgcacg
      781 taaagcccca gccttcgagt tcggcataca tcctggctcc ccgcgcgcgg gcatgttcgt
      841 actcttccag aatgaaacag ccggcgcctt cgccgagcac catgccgcaa cgcgttttgt
      901 cgaacggtcg cggaaggttt ctgatcgtgc ctcgttcatc cggcgccagc gcccgtccgg
      961 cattcatggc cgcatacaca ctcgggtgca ggggggcttc cgttccaccg gcaacaacca
     1021 gcgaggcctg gcctgattta atccattcat aggcacgccc gatcgcgttt gccgtcgagg
     1081 aacaaccgat ggaataggtt tcgcaaggac cgtgcagccc gagaacgatc gcgacttccg
     1141 acgaaatggc attgggaaag gtcatgccca tggtgaaggg attgacccgt tcataggcgg
     1201 tgactttagc tgcgtcgtga aattcaaacg cttctttcat gccgccgatg gaggtgccga
     1261 tgctgatgcc gatcgacccg cggtcttcct gctccagatc gatgcccgaa tcgcgcgcgg
     1321 ccatcatggc ggaggccacg gcaaattggg tcgcccggcc catgcgccgc gcctgtttgc
     1381 gatgcaggaa gtcttcggga tcgaaatccc gcacttccgc tccaaggcaa gcctgaaacg
     1441 gtgaggtgtc gaatgacgta atcggccgta ccgcgctttc gccctggctc aataagtgcc
     1501 aaaacaaatc aactgtcgaa cctaatggag aaattactcc cattccggtg atgacgactc
     1561 gacgagaggt ctgtggtgtc atgatgccct ccagtgctcg taagagcgtg aaaatggttg
     1621 tcgtcaatgg ctatgccacg tgtgcatgtg ttcgcgatgc gcgtccggca acgcggagtc
     1681 aggataaaag gttgcgtaaa agtcttcgtc cagatgatgc gtctgacagg ccacgatcga
     1741 cttgcaggcg tcggcatgcg ccgggaaccg gccgtacgtc gcgaggacat actcggtaaa
     1801 ggcgatggtc gcctcgatgg cgcgttcgga atgctgcggg acctgctgtg ccgtgttgcg
     1861 ctgtacgtag ggttgttcct gtggtttcct gaaggtgccg tcggccccga acttgctctc
     1921 gaccaggttg gtcacagcgt ccttcatcga tggcacgaac ggcggcgtgg gaccttccca
     1981 gactccagga atgccgacgg gattcgcgcg caatggcttg cccgggggga cgacgaagtg
     2041 gaatcccagt ccggggtaga tgtgaggctc catgcccagg aggtgccgac cgcttcccac
     2101 gctttggatt ccgcctccga gcccaagggc ctgctgcata agggagagat gctcgcagat
     2161 gatcccctgc tcctggatgg ccgtttcaca aatcgccgca tcgagttcac gcaggctgaa
     2221 catgcggcgg gctttcatgt cgtcatgcag atgcccgccc gcgcttttcc ggaaggcctc
     2281 gagcccgcag gccgcgttgc cgttgtccgt atcgacgatg aaatagccgg tctcctcgct
     2341 gaacatcatc aacaagagat tcagatacag ggaggcgatg ttggtcaccg gcatgaagag
     2401 ggtagtgccg ggccgattcg tataccattg attgaacgga agcatgaacg gggcttcccg
     2461 gggaatgtcc aatcgggatg attgcagttg tatgacgttc agatcccagg ggtgatccgg
     2521 tcctgcggcg tcggccacga aaaagacccc gtcatcgttg gtgtagaaca gctgcgtagt
     2581 ttgcgcagag cagggactgg ggactgtgcg actgttgaaa ttcatcagcg cattgccttg
     2641 tccgacgctc acccccgggc gtccaacaaa ttgcatatcg ccgaggttgc gtcctgatcg
     2701 gccgatcgcc gcataaatga gatagcgttc ctcttcccgg ctgagtggga ccgggtcatg
     2761 gtgactcgtg tattgcagcg gaccgccagg cagggtcatt ccgcggccga agcggcgcgt
     2821 ttttcgctgt tgtaggaggt cgagcagagt gaatgttgcg tccattgctg caggatgtgc
     2881 ggcaagctgc ttcatagggc ctctccttcc ggtttccctg gggccattcg gccctggccg
     2941 gtcatgtcag tggcagtgat acgttgtgct gacacgtcac gttgcgcgtg acgtgtgtat
     3001 ggggcagact ttacgagagg tatggctcgg cgtcacctac ccatcggggt aggcgaaggc
     3061 tccgttcccg gtcggtcagg tagtgacgga ctgggcggcg cgcgggtcga catgcatggt
     3121 gcgagttagg tcgggcggtt gggatcggac ggagaacgat cgtcactggg cgccgatggt
     3181 ggaatgatgc gatgctgttc accattttgc cagtaggcaa tggcgctcca ccggttttcg
     3241 acgccgatct tctggaagat atttttgaga tgaaatttga ccgtattcaa actgaccttg
     3301 agaatgacgg agatttccca attcgttttg cctgccgcca cccatcgtaa aatttcttct
     3361 tcccgtttac tgagcagcag tgcaggttgc gcctgtcgat tcggggtcca ggctgatttg
     3421 cagcgcatat aactcaaatg gaaatgggga gtgagaatgt cgaggagcag acgcagctta
     3481 tccgcctgtt tggcgtcaaa attactgaag gcaaagtagg agcaggctcc atggtccccg
     3541 cgcacccctg ccgaaagaca ggttttgatg ccgaaatcga gcttgagcga cgtgacgtct
     3601 ctgggctcat tgcccaccgg ttcatcggcg ctggaggtga cggtctggcc cgaggtcagc
     3661 aaacgattga cggcaggatc cgccgcgagg ccctggccca tatacagttg gcagaattct
     3721 cgagggtacg tggagtgtcc gagagaagga tcgatcccgt ggagaagatc gaccgcgccg
     3781 catcctgaaa actcgtacgg cacgacgcgc tgcacggccg acaccagctg ccacaccccg
     3841 tcattccggt tgacggagcg cgcgtcatac ataatctcgc cgagtcgctg aaattccttt
     3901 gcggaaaacg ccggctgact catgccaatt ccttccggcg aacgcaccct gtcccgatag
     3961 ggatgatcag caaccagagg cgttcagaaa ttcggccgtg gttcatgatg aggcagctgt
     4021 atcatcgtga gaacggctga ttgtactgcg accgaaggga cggtatctag ggtaaacggt
     4081 ccctactata gagtgcctag ggtatgaacc gcaacgggga agaatacacg tattatttgg
     4141 tcggacgggg agagaggcag ggaagaacgg gttatcgttg aatttttaag gtaggcccca
     4201 gtgtcagcca cttggtcggg ccaagggcag ccatgtgcgg aaggtgtgcc acataccaga
     4261 ccaccacgtc ctgttcctgg acgccttggt tgtcctcgtc ataccccagt tggccgcgtg
     4321 cgccaaagac ccagggcacg tcttcatcgg gcttggctcg gcgaatcgca acatcatggt
     4381 cggcaaacga gtcccgctcg ccatcgtcct tgagcggggc gtacccgtcc ccgggaagga
     4441 gccacacgcc atgccccgtc ggttgatcgc gcacaaacca cgttcgctga gtcgaggcgt
     4501 gtttgacgtc atttcgttca ttggtatatt tggtccatcc aggcccccag cccttatctg
     4561 gtcctccgtt atcccgtaca aagacttgat ccattccatt cccgttcacg tcgaaatcga
     4621 accgccaata ggggtggtgg atatgatcgg tattgcagga taaccctcgg ctctggatga
     4681 ccgggcggag ttcgccatct tccgaaaaat gccaggattg ataaatgtgg tattccccga
     4741 tgcgcgcata aatgccaagc tccagccact tgacaccatg ggaggtggcg ctttcgacgc
     4801 acaccttgtt gtcgccgcag ttcacgatcg gcaccagatc cacccagcgc aaccgatctt
     4861 gaaatggccc gcaacgaccg ctgtccgcac gggaaccgaa ccaggtgaac ggattccacc
     4921 agacgcgttc tttgacatat ttcacccgca ggaccggcat gctggccttg cccagaacca
     4981 gttccccatc ataggcgacg ttccggatgg ccagtccggt attgtctttg acctcgtaat
     5041 caaagctcca gcggccccag tcgagatgtt ccgacgagga ttcggcaaac cccaggttcg
     5101 gcacagccgc tgcgcaacat agcaggaggg cacccgcaaa acgcctcatt ggttctcctt
     5161 tcctgcctta tcgaggaggc tcgtcgccgg catccaatac gcggtcatcc gtgagatcca
     5221 cctgggccca atacttcgga tcaccgccca ctccttgcga aaatgtaatc cagataacgc
     5281 gatgaccata ccctggatcg tttttgaaaa acccgcgatc cggctgcatc aggaggccat
     5341 gcccttgtag cccgttcacc ttgccggcca gcctggcatc ggcccgcgcc aattcgatcc
     5401 cgcgttgaac atcctgcggc ccttcaggcg gcaggtaccc gtcgattcgt gacgcctgga
     5461 gtaccgtccc gtctttgagc tgtacttgga ccgcgacgtt gtggctgtag ctgaagtatg
     5521 tgagcttggt gaaacgggcc tgttggcggc aacagccgaa ggtaattttg ctggtcggcg
     5581 gcatcgggtc cgcatcaacg aatccccagc gttcccccag aagagaccgc acacgagaat
     5641 cggcctctgc agtttttcgc agcccggcaa tttcggatgt ggaaagagag gctgtaggat
     5701 tcggggaacg agttacggcg gcctcattgg tgctgccggc catcttcggt ttgatgtggc
     5761 ctggagattc gtcagcagta aactccagga catgttttgt tggaacctga gcgggcagtg
     5821 gctttttcgg gatggccgtc tcaggatcct ccggtccgaa ggggccgcgg gacgcggcat
     5881 ccaaactaca gcccgccgcc agtagcagga gcatgatggc ggcgctgttc agcatgatga
     5941 atcgtgtcgc catcgcgtta taccagcgcc agttttcctg ccacgcccaa tgccagccgg
     6001 gaaatctgca ctcccgcttt gatgaccgcc gcgcgctttt tacgggacgc ggcatccaac
     6061 accgctttgc tcatcaggtc tttgtaggtc tcgatctcat cggcttcgaa gggaacgatt
     6121 ttggccacgg tttcattatt aaacgtgttc gccagctgca gatagagatt ggaaatctcg
     6181 gcggcgtaga tgccccgccg taacggatcg tttttgtaga gctcaaactt ttttctcaag
     6241 gcggcgaccg cttccaggag cgctgtttgg cgaactttcg tatcatcatc gcgaccgaca
     6301 ctgaattcga cggcgcccaa ttgatccacc agcacctgcg cctcctcgcg ggcatggtcc
     6361 acgctggtgg agagctgttc gatgtcattg gtggcggact cggcggtttc catcagctgc
     6421 ttgatcacgt tgtcgttgtc ccggaggaag gtgatcaccc cgtcgatgct gcgattcata
     6481 gagccctccg ttactgtccg tcgtctttct tcagtcgatc caggagttcc accagatcag
     6541 cggtgaatct ctgcgcccgg tccaatccgc cgacgcggag gatgcgcgcg ccgacaactt
     6601 cttccagcgc atcgttgacc gttcgggaat ggttgagcac gctcatgatt tgctcagacc
     6661 gtcccggggc ttgatcgaga atcgccgcga cgaattccgg atcgaccgag gctagcgccg
     6721 attgtttggc aaagcgttgg acttcggcat gaagcgtggc ggtgtgtttc caggaatcgt
     6781 tgagcgcgtt ggcggtgtcg cgcagggcgc agaagtcctc ttcaaattga tcccacaccg
     6841 ccttctccag accttgtacg tcggtcatgt agatcaggct tgtcaggtag gccgctgcat
     6901 acgccgcttc gcctcttttg ttcgtgagat tccggaagga cgcgagggca aagcggtgct
     6961 tggcttcctg tatttggaga gacttgaaac tctcatgcag tgaacttcgc gcctgctcga
     7021 ggaatgtgat ccgctcctcg gtctcctttt gaaacagatc gatattggtt tgggcggcat
     7081 cgatcttggt cccttccatc tgaatcagat cacggactga acggctgtga atggaatggc
     7141 agccggtagc catgagcaac agcatggcca gggacagcag cgtcatgcct cgtcggacca
     7201 tggaaggctc cttccgcgga acggtgtagg ggccgctcat cggtgcaccg tgcgcagggc
     7261 gtcggccagc gattgcacgt cggatcggct cgcggtgacg tcgatgtcca gatattgttt
     7321 gatcaagccg ttgattcgtc gaagcgcctc gacattgttc cggtagcggt cgaatgccgt
     7381 gaggtcgacg gtctggggaa tctttgcacc ggctgcgacc tgttgttcga cccgtgcgat
     7441 caagtctggc agttgctgga tgagggtgct catgtctcct gatccggcgg caaacaaggg
     7501 ttgaccgttc ggccctttcc gttccgggag cgatttcaac cgcatcgcat tgaccaacgt
     7561 cagcacgtcg gggccgaggg ccgctgcatc atcctcagcc agtgcggcgt ccggcacgtc
     7621 cgcgacgcgg gggttggtcg tcgcccattg cagggccaga tcgagtttga gacgggtttg
     7681 gacatagcga taccacttca gatgacgggt ggtgacatta ctcacgagct cacggtactg
     7741 ctgcatgagc tgctcattct ccgcataggc ttggtctttg gccgcgagcg cctgtttgat
     7801 ttcaggcggg gtggagcagg cggcgagtga ggcgaagagc agcgtgccgg cgatacgtaa
     7861 catcctcatc gggatgcctc ctggtaagcg tcgtccattc gtatgattct ggtgaaaggc
     7921 aatctacgta cccgatataa atcgtgggga gtcgcgccag agtagtcgtg aaatgaccga
     7981 cctgcaaggg gaaaatcatg atgtgtcgaa tcggcacatc ccgagcctcg tctctcgacc
     8041 gtacccattc agatacgcgt gtatcgaacc gcatacagcg ccagctgcat tccgcgggca
     8101 cgtatgtgtt ggcgggttac gagggaatga gggttttgcg tagagcggca acggtggttg
     8161 catcgaggcc ggccgacttg agttgttcat cggtggccga ggcgatctgc ggaaggctgc
     8221 cgaattgttt cagaaggcgt gaccgacgga tcttgccgat gccgggaatt tggtccagct
     8281 cggatgacag cagcgccttg ccccgtaagt tccggtgata ggtgatagca aagcggtgcg
     8341 cttcatcacg aatgcgctgg accagatgcg tagcgggtga ggttggccgc aatacgatgg
     8401 gatttttccg acccggcaga aagattcgtt catctttttc gccacgcgct ttagccaagc
     8461 ccatgatcgg gatctgttcc tggccgacct gtttcaatcc ttcgagcgca gcgctcaact
     8521 gccccaggcc accgtcgatc aggatcagat cgggccgggc gagatcttcc gtcgcgccgt
     8581 atcgtcgcat caccgcttcc tgcatactgg caaagtcgtt ggcgccttcc accgtctgaa
     8641 tccggaattt gcggtagtcc gattttttcg cttgcccgtc ctcccacacg accagggagg
     8701 cgaccgattg attgcccatg atgttggaaa tgtcgaaccc ctcgatgcga cggggcacgg
     8761 tgtcgaggcg aagcaggcgt ttcagttcgg ctgtggcctg gcgatcgagg gcttcgttcc
     8821 gcagatggtc ggcaatggcg gcggcggcat tttcctctgc gagcaggacc agctggtgct
     8881 ttgcgcctcg ttccggggtg aggagtcgaa ccgtgtcgcc acgtttgtca ctgagccatt
     8941 gctcgatcag cggggcatcg accagatcgg tcgggaccag gagttccttc ggcggctgcc
     9001 cttccttgtt ataaaactgc tcgatggcag aacggacgag ttcctcatca ggggagtcgg
     9061 cggattgcgg ccagaagaaa tcctttcgcc cgatcaggag acctccgcgc acgaacagga
     9121 gctgaaggtc ggctgccgtg ccctgccgtg cgatcccgat tacgtcctga tctgtggtcg
     9181 tgacctgggt aatccgctgt ttctcgagcg tgcgttcgac gctaaagaga cggtcccgca
     9241 ggcgggccgc ttcctcgaat tcctcccgtt ctgccgccga ctccatatcc tggcgtagac
     9301 tgtcgagcag ttcccggtcc cggccttcaa gaaactggcg aacctgtttg acgatcacat
     9361 gatagtcctc acgggactga ttgccggtgc acggtgccat acaccgttta atttcaaatt
     9421 cgatgcaggc ccggtcggcc cgtccgtcga tgtcgatgtc gcacgtggcc agtggaaacg
     9481 ccttgcgaat gactttgagc gtctctcgga gcgcgccggc cggcgtgtag ggcccgtaat
     9541 acagcgcgcc gtctttctga acgcgccgga caatggagag gcgcgggaag gattctttga
     9601 tcggcaaccg gagatagggg tactgtttgt cgtcgcgcag gacgatatta aagcgcgggc
     9661 ggtggcgctt gatcagattg ctttcgagga tcagcgcttc cagctcggag cgggtgacga
     9721 tggtttcgag gtcggcgact tcgctgacca gcaggctggt cttgggggtc tggtcgcttc
     9781 ctttttggaa ataggagcgc actcgatctg ccagcacggc ggctttgccg acatagagaa
     9841 tctctctctt cgcattccgg aagagataac agccgggctg ttctggcaga tggtccagtt
     9901 tggattgaag ggtctcgcac gatccagcca tgagaagtca gccttccgcc accagcgagg
     9961 aacattgcaa ccacgtcgcc agtaattcta acggtcgtag caaatgacct gcaacgtggt
    10021 gctcgcgcgg acgaccgatc gtcgatcgct ggttagcgaa gcgttcgcac gaaggacgga
    10081 ctgaggcttc ctctcgcaac ctccgccact ggtcccttca tcgtcagact gaaatccttg
    10141 gcgacctcga tattgagcgt tccccccggc atgatgacct tcaccggacc tttcaccagt
    10201 ccgagcttga cggcggcgct ggctgccgca caggacgagg agccggaagc ctgagtttcc
    10261 cctgcgccgc gttcccaaat caggatgaag atttcttttg gcccggtggg cacggcaagt
    10321 tgaacattgg tgcgttttgg aaacagagga tggttttcca aggccggtcc cagtgtgagg
    10381 agttcttcac gcgtccagga ttgaccggct tccttgaaga ccacgcagtg gggattgccg
    10441 acgctgacac ccgtaaattg caatgaccgc ccggcagcct cgatgggcgc ctggatcaat
    10501 tcctcgacgg acaacgtgca gggaagggct gagggttgga aggtggctcg gcccatctct
    10561 accgtggccg ccgccgcatc tccatggcga tcgacatgca aggtgatcga aaccagaccg
    10621 ccctttgttt cgaccgtgaa cgcgcgcttt ttcgttttgc cggtggcgtg cagatagcgg
    10681 gcgaagatac ggagtccgtt gccggatttt tcggcttcgc taccatccgg attataaatg
    10741 cggagaccga aatcggcttt cttcgacggg accagcgcga ggatgccgtc gctgccgagc
    10801 ccccaatggc gatcgcaaat gccgcggatt ttcccgggcg taaggttgaa gctgagttcc
    10861 ttgggatcca ttactacata gtcgttcccg agtccgtgcc cgcgaaaaaa cccgttcttc
    10921 atctgcactc tccttgttnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnngc
    11041 ggtacccggc gggcgctcga tgagctccac ttcataaccg tccggtgcgt cgataaagag
    11101 aaaacggctg ccggatgacg taggggtggg accgtcggta atccggacgc ccttggactc
    11161 caggctccgg atggtttcgt ccaggttttc gacctcgaag gccaggtgga ccaggtcttc
    11221 ctggacagtc accggtccgc ttgcgggaaa gctgcacagt tcgatgagtt cgtcgctgtt
    11281 gggaactttt agaaacgcca aatgcgatcc gcgcggagac actttacggt ccatcacttc
    11341 caagcctaag acgttctgat agaagcggat ggtctgatct atgtcgctga cgcgcatccg
    11401 cgtgtggaga agcttggtga ctttcatgag tggtacccca ttcactgtct gcggaacatg
    11461 gtctccatct gcggtttcaa tggtgtgacg ccatttcctc gccgggccgg ccgtcttgcg
    11521 gaggagaatt tcggcgtatc cgggaatcag aaaatttggc atgggtccga tttccttgta
    11581 gccctgcttg cggtagaagg cgcgggcggc ctcattgaag tcggatacgc aggcgaaaag
    11641 attctgggct cgcgcgaacg tgagcgattc gatgtgggag aggaggctac tgccgaatcc
    11701 acgaccggtc gctgaaggcg cgatcccgag taattcgaga taatcgccga acagaaactt
    11761 tctgcgcacg atcgcaatcc ccagcacggc tccctccacc tccagaatga aggtgtcgcg
    11821 cccggccggc agcggcgcga agatgcgcag ccagtccgag gccgcaaacc ccaggcgctt
    11881 ccaggggtcg gagttggtca ggatggcgat cacggcatcg cgatcctctt cgcgcatgtc
    11941 gcgaatcagg gcttgggcgc gactgtcgat tggttgcatc gcagaagatc cgatatggtc
    12001 attggagcga ggcccttgtc aggcaggagc tgtccggcca gggcctcggt cacttcacga
    12061 gtatgtttcc cttttccatt ggcgtgcaag acgatgacgc tgcccggttt gagtcgcttc
    12121 tgaacacggg tcaggatcgc atcggcgctc agcgcggggt cggggtcgcc cgattcgata
    12181 ttccacagaa tgaaacgcag gccgagtgct ttcactgcgt cgactgtctc gtcattgtat
    12241 tccccatagg gtggccggaa cagcgtggcc ggccgcccgt atttagtttt gaggagacgc
    12301 accggtccca tgatttcctg ttgctgctcc tcgacatcat gcatcgggag atgtgcatgc
    12361 acgtcgccat gggtgccgat ctcgaaaaag ggaacggcta agagctgctt cacttcggca
    12421 tcgtgtttga tcatccaccg accggacatg aaaaaggtcg tcggcacctt gtgctcaatg
    12481 aggtagtcga tcaactcgcg atcgaacccc gaagcggtgc gaacggggca cagatcatag
    12541 gtcagtgcca cggcagggca ggaagcagga ccggatttga tgacctgtgc ggacgacggc
    12601 cgggcctctg tgatgaagac caagccgcag atcgcggcga ttcctatcca gcagtctttc
    12661 aagcgcatgc cgcagtatac ccgatggcac gcacctgcga tagttgacgc tttatccggg
    12721 tggctgctac ggtgaaacca tgcagggtcc agattggaaa atcggccgca tgttcggcat
    12781 tcccatccat gtgcacgcct cctggctgtt cgtgtttttc tttatgacct ggtcgctggc
    12841 gacgggttat ttgccggaca cgcttcccgg cttatccgag ccccgctatt gggcgatggg
    12901 cggcgtggcg gcgctcctcc tgttcgcttc cgtcctgctg catgagctcg ggcattcatt
    12961 ggtggcgctg cggtaccgca tcccgatcgg gcagattacg ctgttcattt tcggtggggt
    13021 ggcgcagatg cgaaaagaac ccccccatcc acgggcggaa ttcctgatcg cgatcgccgg
    13081 tccgctggtg agctttatcc tggccggact ttccctcgta ctggtggcgg tcttggaatt
    13141 gtttccggcc gagtcgtctc tgcatggcct gatggcattg ggcaccctgc tcggcatggt
    13201 gaacactcag ttgggtctgt ttaacctcct gcctggattc cccttggacg gagggcgcgc
    13261 attgcgtgcg ggattgtggg cctggagtaa ggattattat cgggcgacaa gccaagcggc
    13321 cctggttgga ctgctgttcg gggtcacgtt cgcgctcttc ggggcgttac tgctgttcgg
    13381 ggctctttcc ggcacggcct ccagcgcctt ggcgagtagc ggcgggtgga ttgtgctgct
    13441 gggcgcgttt ctttttacgg cggcgcgcgg tacccgcaaa caagcagcca ttcgagcttc
    13501 gcttgcgtct gtgccggttc gggaactcat ggtccggaat gtggtggcgc tttctcctga
    13561 tctctcgctg gaggaagcgg tgaaccagta cttcctgcct tacggctatg gagggttccc
    13621 ggtggtgcat gaggaccgcc ttttgggagt cgtggcggtt cgtgatattc aatcggtcaa
    13681 aaattctctc tgggcctttc gccgcgtggc cgatatcatg cagcccgcca gcgacgatat
    13741 ggtcgtctcg ccggatctgt cagcgatgca ggcattggag cagatgatag cggtgggggc
    13801 cgaacgactg gttgtggtcc aggatggtca attgctggga ctggtgacgc gcgcatctat
    13861 cggacatttt atcgagcaac accatccgtc gggacttggc aagtcttctt cgtaaccgga
    13921 cggtttcctt ccctcacatt ccgcataaat agccatccac tgaggcatgt gagacctcaa
    13981 cccgcgtaac tcatccggga agcgtcgccg actcgtcgag gagggctggg cgtcggcatt
    14041 ggcattcgta ggtcaccacg gctcccagga ggaccagtgc cgatgagtag tagacccaca
    14101 gcaacagcaa gacgacctcg agcagtgaac catacagttg cgtgtagacg gcagcgtctt
    14161 ccaaataggt gacgaagaga accttggcgg agacccagag gagactgaat accgcgccgc
    14221 cgatcgtcgc ttcgcgccag gttggccgct gatgaggaag aaagcggtac aaacaagtga
    14281 cggaggcgaa ggccagcagg aatggcaatg tataggtgat gaggaagtca tgggccgcga
    14341 ttgctaccag attcatgccg agaaagcgcg gcgcataggt agtgagtagt tcgatggcct
    14401 gtgtggccac gaaggatatg agcgtcagaa accccagcat ccagatcagg gctacggcga
    14461 ccagcgtgga aattaatgga tgccgtttgg ctgccgtgcc gaacacggtg ttcatggcat
    14521 agtccaattc gtagaacacg agtgcgctga accatccaaa ggccagaaag acggcccatc
    14581 gcacttcctc ctgctcagcc acccgccgga tatccttggc cagccgttcg cccatgctgg
    14641 ggaggaatcc tttcagaaac ccgagcagaa actggtagcc gatcacatcc tggctcacga
    14701 tgaaactgat gccgtagagc agcaggaaga ccatcgggaa gagggagagg atcgagtaga
    14761 acgccaacga agctgccagg ctgggacagc cgcgacgtcg aaaggtgtcg aacacgttgg
    14821 agagaaatgt gagttcagtc atgcagaccg cgcgattcag actcagtgca gagcggtgaa
    14881 tgcttcggat cgttgagagg agccggacaa ggcacggtgg cacatcatcg ggaaatcgag
    14941 gcgccggtca atgtggcgtg acccctgcgc ctggaggcta tttcagcaac ggtgccgcat
    15001 gggtggccag cgaccacagg ccgttgggga agagaccgag aaagacgacg ccggcaaggg
    15061 cacaggccag gacaaaggac agcgcgggag aggtttccag ccgcgagtgc gcagtggcgg
    15121 ctccctcggg ctcgcgcatg tacatcacca tcacaatccg caagtaatag aaggcggaaa
    15181 tagcggcgaa gataaccgcg acgaccgcca gccaggtcat gccgccgttc acggcggcca
    15241 tgaaaatata gaacttgccg ataaatccag cggtcggggg aatgccggcc agcgagacca
    15301 gaaacacgag catgaaaaac gcagccagcg gttcgcgttt ggccagtccg gcataatcct
    15361 cgatgttctc gctctcctgt ccttctttgc gcaacatgcc gaccaaggca aaggctccca
    15421 gggtcatgaa ggaatagacg gcgatataca gtaagacgct ggcgaaaccg ctggacgtcc
    15481 cttcgccgct gtgacgggct gccacgacga caccgatcag ggcgtacccg gcgtgggcaa
    15541 tactggagta cgccagcata cgtttgatgc tcgtctgtac gatggcgacc agatttccta
    15601 acgccaaggt ggcgagacag atgatggtga acaggactga ccaatcggca ctcgcgccgc
    15661 ccaagccttc cacgaacacc cggaggaacg cgccgaaact ggcggctttg gacgccacgg
    15721 ccataaaggc ggtgacggag gtcggagccc cttggtagac gtccggcgtc cacatatgaa
    15781 agggcaccac cgctagcttg aatccgaacc cgacggccag gagtacgagt gccagcgaca
    15841 acatcggatt ggcagtgccg tgcgtggtga tcgcctcggc gatcaccgac aacctggtgc
    15901 tgccggccag gccgaagagc agagagattc cgtacagcaa gacgccggaa gaaaaggctc
    15961 ccagcacaaa gtatttggct gacgcttcca gcgaacgggc ttccgttctc ttcaacccgg
    16021 ccatcacata gagggaaagg gacatcaact cggtgccgag ataaatggtc agcaggtcgg
    16081 cgccggacac catgaccatc atcccgacca aggccagcag aatgaagccg taatattcgc
    16141 cgatgctgag tcgctcggct ttgagatagg ccagtgagag gagaacggtc aggccggtga
    16201 cgatatacaa cagcagcttc cagaaggcgc cgtacgaatc gatcaccacc agattactga
    16261 aggcataggt ttgaccggtc aggtgggacg aggtcaggcc catgcacatc gccagagcgc
    16321 ccaacgtgag ccaggcgagg acgtcctttt tgtctgctcc caggatcggg tccaatgcca
    16381 gaatgaggca ggccgtaccg atgacgatca gttcgggaag aatggccagg agatcttgga
    16441 gtggaaaagt catcgtgccg ctgcctgttc agaagatgag gaagacatgg ccgccatcgt
    16501 tgctgccggt tgcgggagcg caggttgctg cggcgcagtc gcatatgcgg gagccttttg
    16561 tgcgttcaag agattcgtca cgctggcatg catacgggtc aacagcgggt tcgggaagat
    16621 gcccagcacg aagaccagcg caattaaggg aacaagcgtg gcggtctctc tcgcattcag
    16681 gtccaggaga tgtgcgcgat gcgccggtgc gggcgtaccg aacacaaccc gttgcatgag
    16741 ccagaggata taggcagcgg ccaggatcac gcccaatgcg gcgaaggccg tcgcaaactg
    16801 actccagacg aaagtgccgg ccaaaacgag gaattcgccg acgaaactgt tggtgcccgg
    16861 aagtcccaag gaggacaggg caaaaatcat caggaacatg gcgtaacgcg gcatgggacc
    16921 ggccagtccc gtgttgtcga gaatctggcg gctatgagtc cgctcgtaga tgattcccac
    16981 gcacaggaac aagcccccgg tggtgatgcc gtggttgacc atctgcatga ccgccccttc
    17041 aatgccctgg atgttcagca cgaagatgcc cagcgttacg aagcccatgt gactgacgct
    17101 ggaatacgcg atcaacttct tgatatccga ctgcgccagc gccatgtagg ccccatagat
    17161 gatggccacg atcgacaggg cgatcattgg tttggtaaag gccaccgtgg cgtcgggaag
    17221 catcggcaat gtgaagcgga ggaatccgta ggtgcccatt ttcagcaaca cgctcgccag
    17281 aatgacgctg cccgccgtgg gagcctctac gtgcgcgtcc ggcagccagg tatggaacgg
    17341 aaacatcgga accttgaccg cgaaggcggc aaagaaggcc aggaacagcc acatctggag
    17401 cgacgcgcca taggtcccgc ggctgagttc aaggatgtcg aacgtatgcc cgccctggaa
    17461 gtacaacgcc aggatggcga ccagcaggag caggctccca gctaacgtgt agaggaagaa
    17521 cttgatggct gcgtacaggc gattcggacc gccccagacg ccgatgagca gatacatcgg
    17581 aatcagcatg acttcccaga acacgtagaa gagcacgaag tcgagcgcca cgaacacgcc
    17641 caccatggct gcttccatga cgagaagcat ggacataaac agctgcacgc gtttctcgat
    17701 ggccgtccag gacacggtga cgcaaaacgg catgaggaat gtggtcatca gcaccagcgg
    17761 aaagctgatg ccatccatgc ccaggctata gttcaccggc ggagaactga tccaggaagc
    17821 ccgttccacg aactgcatgt tggcggtgga gctgtcgaac aaccaccaga gcggcaagga
    17881 gatgaggaaa ttgccgacgg tgaagccgag cgccacccaa cgcgacgact cagccttgac
    17941 caggaagcag atcaccgctc cgatcaacgg gaaaaatacg atgaggctca accagggaaa
    18001 cgacgtcacg aaaatctact ccacaactga aacacgaagc ctaagacagc gtaccgggcg
    18061 tcagggattc cactcgcttt caactacagc agcaaataca ccgtcaagat gaccaccgcg
    18121 cccaatgtca tgcccagggc gtaatgttgt gtctggccgc tctgtgtcag acggatcaac
    18181 cagccgcccc aggcaaccgc acgggcgact ccattgacgg cgccatcgat gatggccaca
    18241 tcgacatgtt tccacaatcc ctgtgcggcc gacagcgtcg gacggacgaa ggagcggtcg
    18301 taggcttcat cgatatacca cttgtgcaac gacaactcgt aggccgcccg ccactgttgc
    18361 gcgaggcgat ccggcaagcc gggattcagc acatacaggt agtaggccgc gccgattccc
    18421 gtcaggccca tgagcgtcgc cagcgccatg atgcccaagg cggcgcttcc ttcgtgatgg
    18481 gcgcctgcgc cttccccatg aaagaccggt tccagaaacg ccgggatgcc gagatagccc
    18541 gcgacgatac tcaggacggc cagcaccatc aacggcgcgg tcatcgtcgt cgacggctcg
    18601 tgaacatgcc ctgcatggtg cggatcgacg tgggacttgc cccagaaggt cacgaatacc
    18661 aaccggaaac tatagaaggc ggttagtccg gccgtcacca atccgcaaat ggtgaggacc
    18721 tgacccagag gcccggccga ccaggaggag accagcagat cgtccttgct gaagaagccg
    18781 gcggtcagcg ggaacccggc caatgccagt gagcccacga ggaaggtcca ataggtgacc
    18841 ggcagtttgt ctttcaggcc gcccatgtga cgcatgtcct gttcgtgatg cagcgcgatg
    18901 atgaccgagc cgcagcccaa aaagagaagt gccttgaagg ccccatgggt gagcagatgg
    18961 tacatgccgg cgctgtaggc tcctaaaccg caagccatga ccatgtaccc gagctggctc
    19021 atcgtcgaat aagcgaccac acgtttgatg tccgtctggg ttagggcgat ggttgcgccg
    19081 agcatcatcg tgagcgcgcc gaccagggcg acgaccgtca tggcggtggg cgacaggttg
    19141 tacagcgggg ccaatcgcgc gaccatgaag acgcctgccg tgaccatggt ggcggcatgg
    19201 atcaaagccg aaatcggcgt cggtccttcc atcgcatcgg gaagccagac atgcagcggg
    19261 acttgcgcgg atttgccgac ggctccggta aagagcag
//
LOCUS       DAOQPD010000078        18959 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1458_length_18959_cov_23.103470, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000078 DAOQPD010000000
VERSION     DAOQPD010000078.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 18959)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 18959)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18959
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1458_length_18959_cov_23.103470"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..894
                     /locus_tag="PK063_15070"
     CDS             <1..894
                     /locus_tag="PK063_15070"
                     /inference="COORDINATES: protein motif:HMM:NF013088.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HMZ98420.1"
                     /translation="RNMVKVVRTEYPQRSGLIAINLAAIIFGTAALYGRLDIAPLWIV
                     TMRGAFASVALAGVGLLSGGLGLRPTIAQLKRLLVTGILLAIHWVTFFQSVQLAGVAI
                     ATLTFAVFPLFTVLLETMKARRRPSLLELSAGVAIVAAVALLVDTKDSDATLTGTIVG
                     LGSALAFAVFGIKAQILPTEITPLMVSLIQNLVVSLSLTPLLAVSSPAPKTTTDWLGL
                     LLLGVVTTAFMHQLYLFALKRLSATTCSGFIALEPVYAIVFAAVFFGEPLTLWVVVSA
                     VLIIGASVVLLRAERVTVVLD"
     gene            1228..1359
                     /locus_tag="PK063_15075"
     CDS             1228..1359
                     /locus_tag="PK063_15075"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98421.1"
                     /translation="MIEFPLILIGYALLPIIAIQLMIMADRPQQKGEQNAFPQVEIL"
     gene            1688..2371
                     /locus_tag="PK063_15080"
     CDS             1688..2371
                     /locus_tag="PK063_15080"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98422.1"
                     /translation="MKSANALIGLVLLLLATTGCHGYTLLETPTTDGFHSKLPAPYTR
                     AVVWGGRPDTVQSASTWLLKKGLLVVDQTKVLQAAADQKVSLSGYQYLETDVLRMAKL
                     VGARLVVFSNAEVGSWEALDWSNGVPRSQRVYSATIALRAVDVNSGEIEWSGKAQSTE
                     RFSNIEEGISFLTCHALATAWGMRNPGSLAPENICPPGSGLMTTEGTKHHATPAASTR
                     ENLTPSMNN"
     gene            2521..3372
                     /locus_tag="PK063_15085"
     CDS             2521..3372
                     /locus_tag="PK063_15085"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98423.1"
                     /translation="MVRYPLIFLLSWSFFAAPIAEANENHPFWTEQALFHFGEDVFFT
                     GRASCAPNVEEGRQRAYLAAVQEVKNFTRAQEIGGFPLDTQMIFEDSRPADCAPGLVT
                     VWRLLRAPRLALDGLARRGTPGKSADISPILAQVAAVRNLTPRVGMLRDEVWNRYGLP
                     RSIWARPEKGELIWDYSQFGLTIVFNQEDVLTRWRLTGPNPRSSEDTSPAPSQPEPLS
                     GKDLPAIDLTARLQQLEEQQDLERRHEAQRYCSLRFAEVPDTLRPTQGTCEQREYQRL
                     KERHPRF"
     gene            3410..3904
                     /locus_tag="PK063_15090"
     CDS             3410..3904
                     /locus_tag="PK063_15090"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ98424.1"
                     /translation="MTTDKIAHATILLVDDDPSTLLLASKPLQDQGYTVLQAPGSAEA
                     LRLYAEHPRPIHLVVTDIFLPPPGFQLSVEENPYPRVNGLEMVERLLEKKRDIRIILM
                     SSTPGPDLQGRGLIREGLPFLKKPFTSDALLTLIRDTLAGPPATQGPTKPSASGKGEV
                     EWVD"
     gene            4014..5732
                     /locus_tag="PK063_15095"
     CDS             4014..5732
                     /locus_tag="PK063_15095"
                     /inference="COORDINATES: protein motif:HMM:NF037406.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98425.1"
                     /translation="MARAKATEALRSKTKPNAVDELSRGIATLRELSVQIDDLSRDGF
                     PYREAVRARTELSFRETIRRLFGEKSPEYQTHKNHKLKVGTRAESTQSTALLKEFIAA
                     LEIQKADLLGLKPEEVIAMVATEPGRPPLTMVPPVTSTDANTMSSATPPALPAAVAAP
                     IPTTTATIASAVSNPPLSPQAPPSETSRIVAPSTSPSASDTLPPPVRDTLAPRPVQPS
                     ASVSSASGESTQVSQLSSTPIPTTPSPMPPPIVPAPSPGTSGSSAKAAGDATIPTTTI
                     PPITSARSTVPQGTLPPVPHTTLRPRPAPLVSTDIPASTQLSTNVPPPLTPTPAPASE
                     PPRQIVPSVGATTADSSPIPVQENRPTPPLVQTMAPTTTSASPAPQPEPPAPPIVAQV
                     SAPVRSSAPASSQIPIPEKVPEAKTSAEHGTLEILRRVCARFHLVARQLRLRKEYRPT
                     LEITDEYDLQDLFYALLRLQFDEVGTEEWTPAYTNGAPRTSYLLDWEKTVVVVKQTRS
                     GLTTKDLAEQIAADTARYSARPNGANFVCFVYDPDGRVGNPRGLEADLSSTEGTYRVE
                     VIVAPK"
     gene            5853..6107
                     /locus_tag="PK063_15100"
     CDS             5853..6107
                     /locus_tag="PK063_15100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC ligand binding domain-containing
                     protein"
                     /protein_id="HMZ98426.1"
                     /translation="MPDRAYVLINVHPGQTADVVKALADIKEIKQIDPCWGKPDIFTI
                     VEIPHQDALTQLVLAKIHAIPGVEQTDTHNVYRLQETKPK"
     gene            6104..6541
                     /locus_tag="PK063_15105"
     CDS             6104..6541
                     /locus_tag="PK063_15105"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98427.1"
                     /translation="MIRMIAPLLFAIVVAGCAGAPAAPELDVMEVTLEAPADKVQTAV
                     ADVLTQGGYSVDQDESGNVTTGMRQEVRGPWNNLLRWRFGVGKSRVEARIVRQDVSTT
                     RLRLQVFYRGKDGIFDTWQDAETPLPQSAANEIRLIKNALRLL"
     gene            complement(6548..7942)
                     /locus_tag="PK063_15110"
     CDS             complement(6548..7942)
                     /locus_tag="PK063_15110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ98428.1"
                     /translation="MNQAKLFVVDDDETARTLLAEALAKEGYAVEAFASGQAAVERGK
                     QAPPDVVLTDIRMEQGDGFLVLKEFKRFSPDTSIVLLTAFGSLEGAIEAIKQGAYDYL
                     AKPFKRDEIRLVVQRSLEHCRLVRENARFREDARVREPWSHLVGSSPAMLEVYKLVAR
                     VSDGRSTVLIEGESGTGKELIARAVHLNSPRREKPFIPVNCGALPDHLLESEMFGYEK
                     GAFTGAVGAKAGLFEAANGGTLFLDEIGDLGQALQVKLLRVMQEQEVRRVGSTSSVKV
                     DVRIIAATNRDLAARVKEGKFRDDLYYRLNVVRIALPSLAQRQEDIPMLAHHFLQKYA
                     KQSSHVRGFAPDTMALLKRYQWPGNVRELENAVERAVSLSHGPLLLPEDLPESIRAEP
                     GPSDQPAGGLSEGDPDALLTLDEVEKRHLSRVLKETRGNKVKAAKILGIDRRTLYRMA
                     ERFGLDFGDESDEK"
     gene            complement(7956..9107)
                     /locus_tag="PK063_15115"
     CDS             complement(7956..9107)
                     /locus_tag="PK063_15115"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ98429.1"
                     /translation="MKNRNQLVLGIAAVLFLIVTVMEWMFPLNVVGAFGFVLPILLVA
                     TVRNRQLMVMTLALCILVTFIGLFQPAKKKERFTTVVFNRIMVVFVLAGVAYIGVTWE
                     ERKAREEAARAALATQTEHLLRANTQLGELKDTLARSERLAAVGQLVASVAHEVGTPL
                     HSIAWHVEALAEEPGLTAEMQKRIGIIDEQLNRVVRIIQDLLSSTRQRKPEPTWYPAE
                     RLIEPVVALMEPGYHAKGVALQAEVTPAVSVWADAEKIHQVLVNLLTNALAATSTGGQ
                     VVVSVTARPASAEERERGSCTGRTDLDTTVLLVVSDSGCGMPREDMDRAFQPFFTTKA
                     IGKGTGLGLFLSREVVVAHGGQLTLESEVGKGTTATVILPGLPTHPGAA"
     gene            complement(9272..>10672)
                     /gene="malQ"
                     /locus_tag="PK063_15120"
     CDS             complement(9272..>10672)
                     /gene="malQ"
                     /locus_tag="PK063_15120"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: protein motif:HMM:TIGR00217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HMZ98430.1"
                     /translation="GVEQARAADFVDSESVVKAKRTMLDLAYRQFLTENYAGTEPSLQ
                     PTSARGWLLERFIRDEGESLERFALFQVLEEDRRLIEQAPKLWPEWPEQYRNPGTPAL
                     REFARRHRKRVRFFQYVQWVAADQLRAANTRASQVHMTVGLYPDLALGSDRNGAEAWM
                     LQDTLALGADCGAPPDAFAPQGQNWGFAPFNPLRLKATGYRSFIELLRKTLRQGGAIR
                     IDHVMMLFRLFWVPRGLTAAAGAYVQYPAEDLLRILALESMRAQTLVIGEDLGTVPDY
                     VREQLARYKILSYRVFYFERNWDGSCKPPSAYPDQSLAVVTTHDLPTLTGYWSGEDIR
                     LRARLGMYVHEQAVQQAFEERARDKNQFLAALQSAGLLPPGVSAQQESVPAMTPDLCR
                     AIHLYLAGSPAWVVLANLDDVIGEVTQMNLPGTVDAYPNWSRKLSLSLEELQQDERVQ
                     ALAAAIRTLRPSTTPA"
     assembly_gap    10673..10772
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<10773..11089)
                     /locus_tag="PK063_15125"
     CDS             complement(<10773..11089)
                     /locus_tag="PK063_15125"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98431.1"
                     /translation="MKVFTHTRSTTLMYDGTEQDLLCLLASRAGISPEYYDIAGTLHV
                     TSDDTRRAILSAMGFDTTSRESLATTLADWDEASWRQPCDPILILEQGYGPTRWAFRL
                     PLE"
     gene            11148..12170
                     /locus_tag="PK063_15130"
     CDS             11148..12170
                     /locus_tag="PK063_15130"
                     /inference="COORDINATES: protein motif:HMM:NF014017.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HMZ98432.1"
                     /translation="MSVDQASFQDRRPAARDGTSPFQAMYSMSNRLLVRFGTSSWAYE
                     GWRNQIYHRPYASSRFSKDSLAEYATYPTGGTPLFRTVGIDHSFYRPASATQLAHYAS
                     QVPADFHFCSKVWEELTVPAYADLPRYGAKAGKPNPRFLDSHLFREMVLQPFLEALPG
                     HIGPFIFEFQRTGMDPVVFLDALDRFLADLPAGFPYAVEIRNPAVLSPRYRDILLAHQ
                     VAHTYNHWTGMPPLLTQHRLLNERFTAPFVVMRLLTPLGLPYADAVERYAPYNRIVTP
                     QPQMRREAASLIHSASSQGVTPYVLVNNRSEGNAPLTIQAIVEMVTALPDSPALLPSP
                     SRDSMI"
     gene            12232..12963
                     /locus_tag="PK063_15135"
     CDS             12232..12963
                     /locus_tag="PK063_15135"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98433.1"
                     /translation="MTPLLSMFRSGAVFAVAVHCLAPAIPVQAASDHSRVDITGDYRY
                     AYHQPETASEAKQHACREALHQAISTSTAVREHTASIVDSKLFHTLVHTLAAQHVTDQ
                     QILQQSEQGRTVYCKIKAVFQADAVERVLLAQTTSGSEQALDQNRALRILAAHEEPDG
                     MLVITYQAIKRLDWLGTAYQGGLRESADVMVDFYDEQGILVRSSRHPARKTATGDDVM
                     NPGEVGTLKVAKPLNGKTFRVWVVK"
     gene            complement(13046..13873)
                     /locus_tag="PK063_15140"
     CDS             complement(13046..13873)
                     /locus_tag="PK063_15140"
                     /inference="COORDINATES: protein motif:HMM:NF013324.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HMZ98434.1"
                     /translation="MRQGAWSVLGIMGVMLVTSGCVAIEAGHEGVMVEQPFFFGHGGV
                     DPAPTKTGRVWVAPTTKVIEVDIRPLQYSEHFDIISAENAPVSFDAFLIANVVEGRTP
                     ELIGRYGTTWYQNNVKEAFRTFVREEVQRYPLFQLTTDPTTRTKLQDAIAREVQNKLI
                     DKQNMPIRLNRVVVGSILPPKGVVEQTTQTIVQEQRKITMVEFQKAEEAREKAEKQRG
                     IADRAYRESLGLTAPEFVDLRRIEVQKEIVQHAPSALTVIMGLERVGINMPSSGADR"
     gene            complement(14058..14480)
                     /locus_tag="PK063_15145"
     CDS             complement(14058..14480)
                     /locus_tag="PK063_15145"
                     /inference="COORDINATES: protein motif:HMM:NF024834.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="c-type cytochrome"
                     /protein_id="HMZ98435.1"
                     /translation="MNLNRSTHLRMKAWMAGMGLVVLVAALPACESNATNQDAGKPAG
                     GATPADVQVGEAKFSANCAVCHGVRGVGTKQGPPLVHKIYEPNHHADMAFQRAAENGV
                     RAHHWEFGNMPKIEGVTPADVEQIIRYVRWLQREAGIY"
     gene            complement(14477..14653)
                     /locus_tag="PK063_15150"
     CDS             complement(14477..14653)
                     /locus_tag="PK063_15150"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98436.1"
                     /translation="MTPEEFFMYLIIALVIIAPIGARLYRRLTLNRTTQMLREQLHSS
                     QSKPSSTTPPELPR"
     gene            complement(14698..15396)
                     /gene="queC"
                     /locus_tag="PK063_15155"
     CDS             complement(14698..15396)
                     /gene="queC"
                     /locus_tag="PK063_15155"
                     /EC_number="6.3.4.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="HMZ98437.1"
                     /translation="MTPLQPKAVVLLSGGLDSTVTAAIAQQDGYSIHCLTVSYGQRHQ
                     VEVERARAVAAALGTAGHVVVTVDLRAIGGSALTADVDVPKDRPPEARASEIPVTYVP
                     ARNTIFLSLALAYAETVKASAIYFGANVLDYSGYPDCRPDFIRAFETVARLGTKMGVE
                     GHGAEVRAPLLMMSKADIVRRGQALNVPFELTHSCYDPGVEGLACGRCDSCRIRREGF
                     RLAGVVDPVPYAIL"
     gene            complement(15517..16092)
                     /locus_tag="PK063_15160"
     CDS             complement(15517..16092)
                     /locus_tag="PK063_15160"
                     /inference="COORDINATES: protein motif:HMM:NF013427.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA family transcriptional regulator"
                     /protein_id="HMZ98438.1"
                     /translation="MATKVGAKKKTPTTKAKAIAPEKPVKKERPAPVTTMTEKDEDSV
                     AARVVAALTLKETPKEKEERQRRREVLQRMLLGKRQEIMREIEGNLGQSLTEDQQRRL
                     ESARDVGDQALMDLDRELGISLMEMRNRKRQAIDEALTRLSEGTYGICAECGIEVSEK
                     RLEAVPFAKLCVQCQSRQELLEKIEKEEDRD"
     gene            complement(16198..16713)
                     /locus_tag="PK063_15165"
     CDS             complement(16198..16713)
                     /locus_tag="PK063_15165"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HMZ98439.1"
                     /translation="MNYKSLIREVPDFPKPGILFYDITTLLKDPQAFRSIADELAARY
                     EGQGIAKVIGIESRGFILGGTLAARLGAGFVPVRKPGKLPADIYEVEYNLEYGSSVLA
                     IHRDAVSPGERVLIVDDLLATGGTAAATVDLVGQLGGEIAGLDFLIELKALKGRDRLT
                     GFNVHSLIIYP"
     gene            complement(16738..17736)
                     /locus_tag="PK063_15170"
     CDS             complement(16738..17736)
                     /locus_tag="PK063_15170"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HMZ98440.1"
                     /translation="MARRATVRQDSEVGAPVSTRRPRAARAEEDEDAESSGLAESEDS
                     GGESRQAESGRAEGLDTIKSYLREVRKSTLLNFKQEQALGKRVMAGDEAARQEMIEAN
                     LRLVISIGKRYMNRGFPFADIVEEGNLGLIKAVEKFNYKRGFRFSTYASWWIRQYIER
                     AIINQGKLVRLPVHVVERLNRYLGKVEQLVHELGREPLAEEVAAKLKTSVAEVDDLKQ
                     LVRTTCSLDSPISDRQDTFLRDVIEDPLCLTPADTTEGVMRRAELMAWVNELPEKERT
                     VILARFGLDGAESRTLEEIGHEMGLTRERVRQIETAALARLRGIIERKTMKRADLL"
     gene            complement(17751..18038)
                     /locus_tag="PK063_15175"
     CDS             complement(17751..18038)
                     /locus_tag="PK063_15175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HMZ98441.1"
                     /translation="MTEIGESVRARILVSGRVQGVGYRAFTCRMAAARGLTGGVENLD
                     SGQVAVDVEGGRAVLEEFLVDLKKGPVGARVTQVQVEWGNATGRHHDFSIW"
     gene            complement(18359..18435)
                     /locus_tag="PK063_15180"
     tRNA            complement(18359..18435)
                     /locus_tag="PK063_15180"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18399..18401),aa:Pro,seq:cgg)
     gene            complement(18471..>18959)
                     /locus_tag="PK063_15185"
     CDS             complement(18471..>18959)
                     /locus_tag="PK063_15185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HMZ98442.1"
                     /translation="LLDDLYGGRIATCAATESAIERAVMQADLVIGAVLVPGARAPRV
                     ISRSLVSKMQAGAVIVDVAVDQGGCCETTRPTTHSDPVYTVDGVVHYCVTNMPGIVPH
                     TSTRALTNVTLPYLVRLASEGVGKAIHSDPGLAKGVNVMNGKITCQAVAESHGLRFTP
                     LL"
BASE COUNT         3931 a         6053 c         5055 g         3820 t
ORIGIN      
        1 agaaatatgg tcaaggtcgt caggacagaa taccctcaga gatcaggact gatcgcaatc
       61 aatcttgccg ccatcatctt tggcacggcc gcactgtacg gcagattaga tatcgcacca
      121 ttgtggattg tgacgatgag aggagcgttt gcttcagtgg cactagccgg agtgggctta
      181 ctaagtggcg gcctgggtct gcgtccaacc atcgcacaac tcaagcgcct gctcgtgaca
      241 ggcatactgc tggcgattca ttgggtcacc ttcttccaat cagtccagct tgccggtgtg
      301 gccatcgcga cactgacgtt cgcagtcttt cctctgttta cggtgctgct tgaaacgatg
      361 aaggcgcgcc ggcgcccaag cctgctagaa cttagcgccg gggttgcgat tgttgcggca
      421 gttgcgttgt tagtggatac gaaggattcc gatgccacac tcaccggcac gatcgttggg
      481 ctcggttctg cattggcgtt tgcggtgttt gggatcaagg cacagatcct ccccaccgag
      541 ataacacccc tcatggtgtc actcattcaa aatctcgtgg tgtccttaag tctcacgccg
      601 cttctcgcgg tcagctcgcc agcgccgaaa accaccactg actggcttgg cctcctgctg
      661 ctcggcgttg tgacgacagc cttcatgcat cagctctacc tgtttgcgtt gaagagattg
      721 tccgccacga cgtgcagcgg gtttattgcc cttgagccgg tgtacgcgat cgtctttgct
      781 gcagtatttt ttggggaacc cttgacgctc tgggtcgtgg tgagcgcggt gcttattatt
      841 ggtgcatctg tcgtgttgtt acgagccgag cgagtcacgg tcgttctgga ctgactattc
      901 atcacaggtc cgaagcgcca ccagcccctc agaacagcag cccaagatct gccatcttct
      961 ccccccttct cctacgcctc tgcaacgcga gcccccatct cttggatcgc aaggactcag
     1021 gccgtctttc gtcccgttac ccttaggtct tccggctcag cgcaaattgt tctcattgca
     1081 cagttctctc ccttgagttt cggcctccaa aggagcactg ccggcataaa ccatctcgag
     1141 catcagtaca atcaatagct tggcactccg tgggagaacg gtatcgagct tgcagtggag
     1201 gctctacata acaaaaggag ttccaccatg attgagtttc cgctgatcct tataggctat
     1261 gcacttctgc cgatcattgc cattcagttg atgatcatgg ctgaccgtcc ccaacagaag
     1321 ggcgaacaaa acgcctttcc acaggtcgaa atcctgtaag cctgcggcgg cttcacaagc
     1381 catgagtgaa gccgccgcct ttccaggccg tcgttgactc ccgcctcctt cccgactgcg
     1441 gcaattcaca tcccagactt gcgttgagca ccaccgccgg ccgaggctcc cacaatttca
     1501 tcctgtaagt aagtagcggt atctcgagag cgccaacacc caatgtactc gacgaatgca
     1561 gcagacgtag gtagaatcaa tcctgtataa tgaggccgaa acattgagtg cccatccagg
     1621 aagcacgaac cgttcttgat aaagattcat ggcgagcagt cagcacacat ccttccataa
     1681 agagtccatg aaatcggcga atgcattgat cggtttggtt ctgctcctcc tcgccacgac
     1741 cggatgccac gggtataccc tcttagaaac tcccacgact gatggatttc actctaaact
     1801 tcctgcgccc tacaccagag cggtcgtttg gggcggacgc ccagatacgg tgcaaagcgc
     1861 aagtacctgg ctgcttaaaa aaggtcttct cgtcgtagac caaaccaagg tcttgcaagc
     1921 cgcagccgat caaaaagtca gtctttcggg atatcagtat ctcgaaacag acgtgcttcg
     1981 aatggcgaaa ctggttggtg cccgactggt ggtctttagc aatgccgagg tagggtcttg
     2041 ggaagcactg gactggagta acggggtacc gcgcagtcaa cgcgtgtact ctgcgacgat
     2101 tgcgctgcgg gccgttgatg tgaactccgg cgaaattgaa tggagcggga aagctcagtc
     2161 caccgaacgc ttcagcaaca tcgaggaggg aatcagcttc ctcacctgcc atgccttagc
     2221 cacagcctgg ggcatgcgta accccggctc cctcgctccc gaaaacatct gtcctccggg
     2281 gtccggcctc atgacgaccg agggcaccaa gcaccacgcc acccctgcag cctcgacgag
     2341 agaaaatctt accccctcca tgaataacta ggccgcgcat ctcttcgcgg gctattgcct
     2401 cgccgacgct ctttcctaca gtgcctctcg cacaaactcg ctcttttgtc gattttcttg
     2461 tccggcgcgt tatactgcat gagtgactcc ctcttacggc tcttttattg agtgttgcct
     2521 atggtgcggt acccgctcat ttttctcctg agttggagct tttttgcggc gccaatcgcc
     2581 gaggccaacg agaatcaccc gttctggacg gaacaagccc tctttcattt cggtgaagat
     2641 gtctttttta cggggcgagc ctcctgcgca cccaacgtag aagaagggcg gcaacgcgcc
     2701 tacctcgccg ctgtccagga ggtcaaaaat ttcacgcggg cccaggaaat cggcggattt
     2761 ccgctggaca cccagatgat ttttgaagac agccgtccgg ctgactgcgc cccgggattg
     2821 gtgacggtct ggcgcctttt acgtgcgccc cgcctggccc tggacggact cgcaagacgc
     2881 ggcacccccg ggaagtcggc cgacatttcg ccgatcctcg cacaagtcgc agcagtgaga
     2941 aatctcacgc ctcgtgtagg aatgttgcgt gacgaggtct ggaatcgata cggcctgccg
     3001 cgatcaatct gggcgcgccc cgaaaagggt gagctgatct gggattactc gcaattcggc
     3061 ctgaccatcg tcttcaacca ggaagacgtc ctgacgcgct ggcggctgac cggacccaat
     3121 ccacgatcca gcgaagacac ctccccggct ccatcccaac cggagcccct cagcggcaag
     3181 gatcttcctg ctattgacct cacagcccgc ctccagcaac ttgaagaaca gcaggacctc
     3241 gaacgccgcc atgaagccca gcgctattgc tcgttgcgtt tcgccgaggt gccagacacg
     3301 ttgcgtccca cccaaggcac ctgtgagcaa cgggaatacc aacgactcaa ggagcgccat
     3361 ccccgatttt gatccgtctc ccgagtcact gccacgaagg agggccggca tgaccaccga
     3421 caaaatagcg cacgcgacaa tcctcctcgt tgacgacgac ccctcaacgc tcctgctggc
     3481 gtccaaacca ctgcaggatc agggatacac ggtactgcag gcaccgggca gtgccgaagc
     3541 gctcaggctc tatgcggaac acccaaggcc catccatctc gtcgtcacgg acatctttct
     3601 cccacccccc ggcttccaac tttccgtcga ggagaatcct tacccccgcg tgaatggtct
     3661 cgagatggtc gaacgcctgc tcgagaaaaa gcgagacatc cgcatcattc tgatgtccag
     3721 cactccagga cctgacctgc agggccgcgg ccttatccgt gagggcttgc ccttcctcaa
     3781 aaaaccgttt accagcgacg cgctgctgac actcatccgt gacaccttgg ccggacctcc
     3841 ggcgacacag ggcccgacaa aaccttctgc atccggcaag ggagaggtcg agtgggtcga
     3901 ctgacccgga tccatcctca ccggcacccc cacgtcgacc acgagtaaaa gcagggattg
     3961 cttgtcaggc tccaccccct cggatagact tttctcacga gagggagact cgcatggcac
     4021 gagcaaaagc aaccgaggca ttacgtagca aaaccaaacc gaacgcggtt gatgaactct
     4081 cacgaggcat cgccaccctg cgggagctga gcgtccagat tgacgatctg agccgagacg
     4141 gatttcccta ccgggaagca gtccgcgcca gaaccgaact ctcctttcgg gaaaccatcc
     4201 gccgattgtt tggtgaaaaa tctccggaat atcagacgca caaaaatcat aaactcaagg
     4261 tcggcactcg cgcagaatcc acacagagca cggcgcttct gaaggagttc atcgccgcac
     4321 tcgaaatcca aaaagctgac ttgctcggtc tcaagcctga ggaggtcatc gccatggtcg
     4381 cgacggagcc gggtcgtccg ccgctgacga tggtgccgcc cgtcacatcg accgacgcca
     4441 acaccatgtc gagtgcgaca cctccggctc tgccggcagc tgttgctgct ccgatcccca
     4501 ctacaacggc gaccattgcc agtgccgtct ccaatccgcc tctttcgccc caagctccgc
     4561 cctcagaaac atcacggatc gtcgcccctt caacgtcgcc atcggcctcg gacaccctgc
     4621 ccccgcctgt gcgggacacc ctagcacctc gccccgttca gccatcggct tcggtcagtt
     4681 ccgcttctgg cgaatccacg caggtatcac agctcagtag taccccgatt ccgacgacgc
     4741 catcgcccat gccccctcca attgtcccgg caccatcgcc tggaaccagc gggagcagtg
     4801 cgaaggccgc gggagatgca acgattccta caaccaccat tcctccaatc acatcggcaa
     4861 gaagtaccgt gcctcaaggc acccttccac cggttcccca cacgaccttg cgaccgcgac
     4921 cagcaccact cgtcagtacc gacattcccg cttcaactca gctgtcaacg aatgttccgc
     4981 cccccctgac gccgacgcct gctccggctt ctgagccacc ccggcagata gttccctcgg
     5041 taggtgcaac cacggcagac tcaagcccta ttcctgttca agagaaccga cccacgcctc
     5101 cgctcgttca gaccatggcg ccgacaacga ctagcgcaag ccctgcaccg cagccggaac
     5161 cgcccgctcc acccatcgtg gcgcaggtat ccgcaccggt ccgatcatca gcgcccgcat
     5221 cctcccagat ccccatcccg gagaaggttc ccgaggcgaa aacctccgcc gagcatggca
     5281 cgctggaaat actgagaaga gtctgcgccc ggtttcacct cgtcgcccga caactgcgac
     5341 tcagaaaaga ataccgtccg acgcttgaaa tcaccgacga gtatgacttg caggatctct
     5401 tctacgcgct cctccgattg cagttcgatg aggtcggcac agaagagtgg actccggcct
     5461 atacgaacgg cgcgccgcgg accagctatc tccttgattg ggaaaagacg gtcgtggtcg
     5521 tcaaacagac ccgctccgga ctgacgacga aagatctcgc cgaacagatc gccgcagaca
     5581 cagcccgcta ctccgcgcga ccgaatggag cgaacttcgt ctgctttgtg tatgacccgg
     5641 acggacgtgt gggaaatccg cgtggattgg aggctgacct ctcatccact gaggggacat
     5701 accgcgtcga agtcattgtg gcgcccaagt gacatcgcat cgtcaccaag gcagacgtgc
     5761 gtgcatcgtg ttgacttcat ccggagcaat ccgataggtt tcgattcgcg tgaggcctaa
     5821 ccacctgcgc tagttcaagg gagatcctct ccatgcccga ccgcgcctac gtattgatca
     5881 acgtccatcc cggtcaaacc gctgatgtcg tgaaggcctt agcggacatt aaagaaatca
     5941 aacaaatcga tccctgttgg ggcaagcccg acatcttcac catcgtggaa attcctcatc
     6001 aggatgcctt aacccagctt gtgctggcga agattcacgc cattcctggc gtcgagcaaa
     6061 ccgataccca caacgtctat cggcttcagg agacaaaacc caaatgatcc gcatgatcgc
     6121 gccgcttctg ttcgccatcg tggtagccgg atgtgccgga gcccccgccg ctcctgagct
     6181 ggatgtgatg gaagtgacgc tggaagctcc tgcagacaag gtccaaaccg ctgtcgctga
     6241 tgtgctcaca cagggaggct actccgtcga tcaggatgag agcggcaacg tgacgactgg
     6301 aatgagacag gaagtcagag gtccgtggaa caacttgttg cgctggagat ttggtgtagg
     6361 aaaaagccgg gtggaagcgc gcatcgtgcg gcaagatgtc agcaccacac ggctacggct
     6421 gcaggtgttc tatcggggca aagacgggat cttcgatact tggcaagatg cggagacccc
     6481 cttgccgcag agcgccgcca acgagatccg cttgatcaag aacgccctgc ggttgttgta
     6541 gtccagacta cttctcgtca ctctcatcgc cgaaatccaa cccgaatcgt tccgccattc
     6601 tgtacaacgt ccgccggtcg attcccagga tcttcgccgc cttgacctta ttgcccctgg
     6661 tctctttcag cacccgtgag agatgacgct tctctacttc atccaaggtc agcaacgcgt
     6721 caggatcccc ctcggacagt ccaccggcag gctggtcgga cggaccgggc tcggctcgga
     6781 tcgattcggg gagatcttcg ggtaacagca gcggaccatg actcaaggac acggcccgtt
     6841 ccacggcatt ttccagctct cgcacattgc ccggccactg atagcgcttc aacaacgcca
     6901 tcgtgtcagg ggcgaaccct ctcacatggg aagattgctt ggcatacttc tgtaaaaaat
     6961 gatgggcgag catcggaata tcttcctgtc gctgagctaa cgagggcagt gcaatccgca
     7021 ccacattcaa ccgatagtac aaatcatcgc ggaatttgcc ctctttgacc cgggcggcaa
     7081 ggtcccgatt cgtggcggcg attatacgaa catcaacttt cacagaggac gtgctgccca
     7141 cccgccgcac ctcctgttcc tgcatcacac gcaacagctt cacctgaagc gcttgcccga
     7201 gatccccgat ctcgtccaaa aacagcgtcc cgccattggc cgcctcaaat aatccagcct
     7261 tcgcgcccac ggctccggta aacgcgcctt tttcataacc gaacatttcc gattcgagca
     7321 gatgatcggg aagagcaccg cagttcaccg gaataaatgg tttctcgcga cgcggactgt
     7381 ttaaatgaac cgcgcgggca atcaactcct tgccggttcc gctttcccct tcgatcagca
     7441 ccgtgctccg cccatcggat acgcgggcga cgagcttgta gacctccaac atcgcgggac
     7501 tgctgccaac cagatgcgac cagggttcac gcacgcgcgc atcttcacga aaccgggcat
     7561 tttcccgaac gagacggcaa tgctccaagc tgcgctgcac gaccaggcga atctcgtccc
     7621 gcttgaaggg tttcgcgagg tagtcatagg caccttgctt gatggcttca atcgcgccct
     7681 ccaaggatcc gaacgccgtc agcaacacga tcgaggtatc cgggctgaat cgcttgaatt
     7741 ctttcaacac caaaaacccg tcgccttgct ccatgcggat gtcggtgagc accacgtcgg
     7801 gaggcgcctg cttgccacgc tccaccgccg cctgcccgct cgcaaaggcc tcgaccgcat
     7861 acccttcttt cgcgagcgct tccgccagta aggtccgggc agtctcatca tcatcgacca
     7921 caaacagttt tgcctgattc atcagccttg cgctcctacg ctgcgccggg atgcgtcggc
     7981 agcccgggaa ggatcacggt cgccgtcgtc ccttttccga cttcactctc cagtgtcagc
     8041 tgaccgccgt gtgccacaac gacttcccgg ctgagaaaca atcctaagcc ggtccctttc
     8101 ccgatcgcct tcgtggtaaa aaacggctga aaggcccgat ccatatcttc acgcggcatt
     8161 ccgcatccgg agtcggacac cacgagcagg accgtcgtgt cgagatcagt ccggcccgtg
     8221 caggatccgc gttcccgctc ctccgctgat gccgggcgtg ctgtcaccga caccaccacc
     8281 tgccctcctg tgctggtcgc agccagcgcg ttggtgagga gattcaccaa gacttgatga
     8341 atcttttcgg catccgccca caccgacacc gccggcgtga cctccgcctg aagcgccacg
     8401 cccttcgcgt gataccccgg ctccattaat gccaccaccg gctcaatgag ccgctcggcc
     8461 ggataccagg tcggttcggg cttacgttgt ctcgtcgacg agagaagatc ttgaatgatc
     8521 cgtaccacac gattcaactg ttcatcgatg attccgatcc gcttttgcat ctccgccgtg
     8581 agcccaggct cttccgccaa cgcctccaca tgccaggcga tggagtgcaa gggcgtcccc
     8641 acctcgtgcg ccaccgatgc gaccaattgc cccaccgccg ccaaccgctc agaccgcgcc
     8701 agtgtatcct taagttcgcc caactgcgtg ttggcgcgga gcagatgctc cgtttgagtc
     8761 gccaatgcag cccgggccgc ttcttcccgg gccttccgtt cctcccaggt cacgccgata
     8821 taggccaccc cagccagaac gaagacgacc ataatgcgat tgaataccac cgtcgtgaac
     8881 cgttcttttt tcttcgccgg ctgaaacagc ccgatgaatg tcaccaggat acagagcgcg
     8941 agcgtcatca ccatgagttg ccgattccga acggtggcca cgagcaatat cggcaacaca
     9001 aacccgaatg cgccgaccac attcagcgga aacatccatt ccatcaccgt cacgatgagg
     9061 aacagaacgg cggcaatacc gaggacgagc tgattgcggt tcttcatcac gatcggacgc
     9121 cttggggaaa gaacgggcgt gccagtaatg ttcgcgtcac cagggccacc cagatgctag
     9181 gcacctcgag ccctcgcccc accgcgcttg tctagactgt tgaaaccgct ggcggggcag
     9241 gcaccacgcc gaagctgtgt cccgcattgg cctaagcggg cgtggtagaa gggcggagcg
     9301 tacgaatcgc ggcggcgaga gcttgtacac gctcatcctg ttggagttcc tccagcgaca
     9361 gcgacaattt gcgtgaccag ttcggatagg cgtctacggt accaggcaaa ttcatctgtg
     9421 tcacttcacc gatcacatca tcaaggttgg ccaataccac ccaggctggc gagccggcaa
     9481 gatacaggtg aatcgcccgg cacaagtccg gtgtcatggc cggcacagat tcctgctgcg
     9541 cgcttacacc gggaggcaac agcccggcgc tctgcagcgc tgcgagaaac tgattcttgt
     9601 ccctggcccg ttcctcgaag gcctgctgta ccgcctgttc atgcacatac atcccgagcc
     9661 tggcgcgcag tcggatatct tccccgctcc aatacccggt caatgtcggg agatcatgcg
     9721 tcgtcacgac ggcgagcgat tgatcgggat aagccgacgg cggcttgcag gacccgtccc
     9781 agttccgctc gaagtagaac acgcggtagg acaggatttt gtaccgggcg agttgttcgc
     9841 gaacataatc cggcaccgta cctaggtctt caccaataac cagggtctgc gcacgcatgc
     9901 tctccagcgc aagaatccgc agcagatctt cggccggata ctgcacatag gctccggctg
     9961 cggcagtcaa cccgcgaggc acccagaaca gccggaacaa catcatgaca tgatcgatgc
    10021 gaatcgctcc gccctggcgc aaggtcttcc ggaggagctc gatgaacgaa cgataccctg
    10081 tcgccttcag acgcagcggg ttgaacggcg cgaatcccca attctgcccc tgtggagcga
    10141 acgcatccgg tggagcgccg cagtctgcac ccagcgccag cgtatcctgc aacatccagg
    10201 cttctgcgcc gttgcgatcg cttcccaacg ccagatcagg atacaggccg accgtcatgt
    10261 gcacctgtga ggcgcgggta ttggcggcgc gaagttgatc agccgcgacc cactgcacat
    10321 actgaaaaaa cctaacgcgt ttgcgatggc gccgcgcaaa ttcccgcaac gccggcgtgc
    10381 cgggattccg gtactgttcc ggccattcag gccagagctt cggagcctgt tcgatcagac
    10441 ggcggtcttc ttccagcacc tggaacaagg caaatcgttc cagcgactcg ccttcatccc
    10501 ggatgaatcg ttccaacaac catcccctgg cactggtggg ctgcagcgac ggctctgttc
    10561 ccgcataatt ctccgtcagg aattgccgat aggccaaatc cagcatcgtg cgcttggcct
    10621 tgaccacgga ttcagagtcc acgaagtctg ccgcgcgtgc ctgctccacg ccnnnnnnnn
    10681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nntcctccag gggaagacga aaggcccatc
    10801 gagttggacc atacccctgt tcgagaatca gaatcggatc gcagggttgt ctccacgagg
    10861 cctcgtccca gtcagccaag gttgtggcca acgattctcg cgacgtcgtg tcgaacccca
    10921 tggcagaaag gatggcgcga cgcgtgtcgt cgctggtcac atggagtgtc ccggcgatgt
    10981 cgtaatactc gggggaaata ccggcccgcg aggcgaggag gcacaggagg tcttgctcgg
    11041 taccgtcgta cataagtgtc gtggaccgag tgtgagtgaa gaccttcatc aagtcaaggc
    11101 gtcctacgct tttccgcagg gttgcgatac aatccccgca tgaacagatg tctgtcgatc
    11161 aggcctcttt ccaggaccgg cgcccggctg cccgcgacgg cacctctccc ttccaagcga
    11221 tgtactcgat gagcaaccgg ctgttggttc gttttggcac cagttcatgg gcctatgaag
    11281 gctggcggaa ccaaatctat caccgtccct atgcgtccag ccggttctcc aaggatagtc
    11341 tggctgagta tgcgacgtat ccaacaggcg ggacgccgct ctttcgcacc gtcgggatcg
    11401 accattcctt ttatcgaccg gccagcgcca cgcagctcgc gcattacgca agccaggttc
    11461 cggctgattt ccacttttgc tcgaaggtgt gggaagaact gacggttccc gcctatgccg
    11521 atcttccacg atatggcgcc aaggccggaa aacccaaccc tcgatttctc gatagccatc
    11581 tctttcgcga gatggtgttg cagccgtttc tcgaagccct tcccggtcac attggcccct
    11641 tcatctttga gtttcagcga accggaatgg accccgtcgt cttcctcgat gcccttgacc
    11701 gtttcctggc cgacctgcca gccgggtttc cctacgccgt ggagatccga aatcctgccg
    11761 tcctgagccc tcgttatcgg gacattctcc tcgcacacca ggtcgcgcac acctataacc
    11821 actggaccgg aatgccgccg ctgctgaccc agcatcgtct cctcaacgaa cggttcacag
    11881 ccccatttgt cgtgatgcgc ctcctcactc cgctcggtct cccctacgcc gacgccgtgg
    11941 agcggtatgc cccgtacaat cgcatcgtca ccccgcagcc gcaaatgcgc cgggaggccg
    12001 cctcgctgat tcactccgct tcctcccaag gcgtgacgcc ttacgtattg gtcaataacc
    12061 gctcggaagg caatgcaccg ttgaccatcc aagcgatcgt cgagatggtg acggcgcttc
    12121 cggactcccc cgcattgctg ccgtctccct cgcgtgatag catgatctga cgtgagcacc
    12181 gccctgaacc tgcacgcacc agaatccgac aggaaagagg aggtatctcc catgaccccg
    12241 ctgctgtcga tgttccgaag cggcgccgtc ttcgcggtcg ccgttcactg cctggcccca
    12301 gccattcccg tccaggccgc atcagaccac tcccgtgtcg acatcaccgg cgattatcgt
    12361 tacgcctatc accagcccga gacggcatcg gaggccaagc agcatgcctg cagggaagcg
    12421 ctgcatcagg ccatcagtac ctcgacggcc gtgcgtgaac ataccgcctc gatcgtcgac
    12481 tcgaaactgt tccacacgct cgtccatacc ctggctgctc agcatgtcac cgatcaacag
    12541 atccttcagc aaagcgaaca gggccgcacg gtgtactgca agatcaaggc agtcttccaa
    12601 gcggacgccg tggagcgagt cctcctggct cagaccacga gcggatcaga acaggccctg
    12661 gatcagaatc gggcgctgag aattctggcc gcgcatgagg agccggacgg gatgctggtg
    12721 atcacctacc aggcgatcaa gcgtctcgat tggcttggca ctgcctatca gggaggattg
    12781 cgcgaatcag ccgatgtgat ggtggatttt tacgacgagc aagggatcct ggtgcgcagc
    12841 agccgccacc ccgccagaaa aacggcgacg ggtgatgacg tgatgaaccc cggcgaggtg
    12901 gggaccctca aagttgcgaa accgctgaat gggaaaacct tccgtgtgtg ggtcgtgaag
    12961 taacccccaa aatgcaggaa gcaaaacagg atccccggtt ttgcttcccg tttcgcgata
    13021 cccctgaatc agcggcacga attcgttagc gatcggcgcc ggacgacggc atattgatgc
    13081 cgactcgttc caatcccatg atgaccgtca gggctgacgg cgcgtgctga acaatttcct
    13141 tctgcacctc gatccggcga agatcaacaa actccggcgc ggttagtccc aacgattccc
    13201 gataggcccg gtcggcgatc ccgcgctgct tctcagcctt ttcacgcgcc tcttcggctt
    13261 tttgaaactc caccatcgta atcttgcgct gttcctgcac gatagtttgc gtggtctgtt
    13321 cgaccacgcc cttcggcggc agaatgctgc cgacgaccac gcgattgagt cgaatcggca
    13381 tattctgttt atcgatgagc ttgttctgaa cctctcgcgc aatggcatcc tgcaactttg
    13441 ttctggtcgt cggatcggtc gtcagctgaa agagcggata ccgttgcact tcttcccgca
    13501 cgaaggtgcg gaacgcttct ttcacattgt tctggtacca ggtggtgcca tatcgcccga
    13561 tgagttcagg cgtcctccct tcaacgacgt tggcaatcag gaaggcatcg aaggataccg
    13621 gagcattttc tgcggagatg atatcgaaat gttcggaata ctgtaatgga cggatatcca
    13681 cttcgatcac cttcgtcgta ggtgccaccc acacccgtcc ggtcttggtc ggcgccggat
    13741 ccactccgcc gtggccgaag aagaatggct gttccaccat gacgccctca tgaccggcct
    13801 cgatcgccac acagcctgaa gtcaccagca tcactcccat gattccgagc acggaccagg
    13861 ctccctgtct cataggttcc tccaatgaaa aggtccgacc accgagccga attccctgag
    13921 cgggggaact cacggccacg tgttgtcgtg cggatacctt acgaaccgcg tgcgcggttg
    13981 tcaaaccagg cttgaggatg aagagaagac gagaaaagtg aggagaagcg caaccaaacg
    14041 gacggcaagt cggccggcta gtaaattccg gcctcgcgct ggagccaccg gacgtatcga
    14101 atgatctgtt ccacatcggc cggcgtcacc ccctcgatct tcggcatatt gccgaactcc
    14161 caatggtggg ctcgaacacc gttttccgcc gcgcgctgga acgccatatc ggcatgatgg
    14221 ttcggttcat agatcttgtg gaccaacgga ggtccctgct tggtgcccac accacgaacc
    14281 ccgtggcaga cggcacaatt ggcactgaac ttcgcctcgc cgacctgcac atcggccggt
    14341 gtggcgcctc cggcaggctt gcctgcatcc tgattggtgg cgttcgattc gcaggcaggc
    14401 agggccgcaa caagaacgac caatcccatt cccgccatcc aggctttcat ccggaggtgt
    14461 gtggatctat tcaagttcat cggggtagct ccggcggggt cgtcgaggac ggcttggatt
    14521 gtgaagaatg caattgctcg cgcaacatct gcgtggtgcg attcaacgtc aaccgccggt
    14581 agagccgggc gccgataggc gcaatgatca ccagcgcgat gatcagatac atgaaaaatt
    14641 cttcaggcgt catgggccca tctctcctga ctcataggca accgcaccaa ccgttcgcta
    14701 gagtatcgca taggggaccg gatccacaac tcccgctaga cggaatcctt cccgccgaat
    14761 ccggcaactg tcacaccggc cgcaggcgag cccctcgacg ccaggatcgt aacaactatg
    14821 cgtcaactcg aagggaacgt tgagcgcctg cccgcgccgc acgatgtccg ccttggacat
    14881 catcagcagg ggcgctcgaa cctcggcccc atgcccctca acccccatct tggttccaag
    14941 ccgggccacg gtttcaaacg cgcgaataaa atcggggcgg caatccgggt atcccgaata
    15001 gtccaggacg tttgctccga agtagatggc cgaggccttc actgtctccg cataggccaa
    15061 tgccagcgag aggaagatgg tattgcgggc gggaacatag gtcacaggga tttcgcttgc
    15121 ccgtgcttct ggtgggcgat ccttaggcac gtccacatcc gccgtgaggg ccgaccctcc
    15181 gatggcccgt agatcaactg tgaccaccac gtggccggca gtgcctagcg ccgcagcaac
    15241 ggcacgggcc cgttcgacct ccacctggtg acgctgtcca taggagaccg ttagacagtg
    15301 aatgctatac ccgtcctgct gcgcgatggc ggccgtcacg gtggaatcca agccaccgct
    15361 caagaggacc acggccttcg gctggagagg agtcatagac gcggggaaga ataaggggga
    15421 atcgcgaagc cggtcacagg tgagcgagtg accggcttct catatcgatg cattccgcat
    15481 acatgcggtg gaaacggaag gggttgcccg attcggttag tcccgatcct cttccttctc
    15541 aattttctcg aggagttcct ggcgagactg gcattgcacg cacaacttgg cgaagggcac
    15601 cgcctccaaa cgcttctcac tgacttcgat gccacattct gcgcagatac cgtaggtccc
    15661 ttcgctgagc cgcgtcagcg cttcgtcgat ggcctggcgc ttccggttcc gcatttccat
    15721 cagagaaatg ccgagctcgc gatccagatc catgagcgcc tgatcaccca catcgcgggc
    15781 cgactccagc cggcgctgct gatcttcggt cagcgactgg ccgaggttgc cctcgatctc
    15841 gcgcatgatt tcctggcgct tgccaagcag catccgctgc aggacttcgc gccggcgctg
    15901 acgttcctct ttctctttcg gcgtttcctt aagcgtcaac gcggccacca cgcgtgcggc
    15961 cacgctgtct tcgtcttttt cagtcatagt tgttacagga gccggtcgct ctttcttcac
    16021 gggtttttca ggagcgatgg cttttgcttt cgtcgttggt gtttttttct tcgcgccgac
    16081 tttcgtcgcc atagagtctc atgccctttc gtgatgagtg caaggcgaaa aagtttggca
    16141 ggtatatcac gctatagatc gtttgacaag tacccgcttc cccaagatct tggggattta
    16201 tgggtaaatg atcagggagt gcacgttgaa cccggtcaag cggtcacgtc ccttgagggc
    16261 tttcaattcg atgaggaagt ccaggccggc aatctccccg ccgagttgac cgaccaagtc
    16321 gacagtcgcc gcggccgtgc cgcctgtggc cagcaaatcg tccacgatca ggacacgctc
    16381 tccgggcgat acggcatccc gatggatcgc gagcacgctg gatccgtatt cgagattgta
    16441 ttcgacttca tagatgtcgg cgggcaattt accgggcttt ctcaccggca cgaacccggc
    16501 gccaagtcgc gccgccagcg taccgccgag aataaacccg cgcgactcga tcccgatgac
    16561 cttcgcaatg ccctgcccct cgtaacgagc ggccagctca tcagcgatgg atcgaaaggc
    16621 ctgtggatct ttcaggagcg tggtgatgtc gtagaagagg atgccgggct taggaaagtc
    16681 gggaacttcg cggatgaggg acttgtaatt catgggcatg atcgaatcgg gacgttctca
    16741 taaaagatcc gcccgcttca tggttttccg ttcaatgatc ccgcggagcc gtgcaagcgc
    16801 cgcggtttcg atttggcgga cccgctcgcg agtcagcccc atctcatggc cgatctcttc
    16861 taacgtccgc gactccgccc cgtcaagtcc aaaccgcgcc aaaatcacgg tacgttcctt
    16921 ttcgggcaat tcattgaccc aggccatgag ttccgcccgt cgcatcacac cttcggtcgt
    16981 atccgcaggc gtaagacaga gcggatcttc gatcacatcg cgcaggaagg tgtcctgccg
    17041 gtcgctgatc gggctgtcga gtgaacaggt ggtgcgaacc agctgtttca gatcgtccac
    17101 ctcggcgaca ctggttttca acttggccgc cacttcctca gccagcggtt cccgaccgag
    17161 ttcatggacc aattgttcta ccttaccgag gtaccggttc aaccgttcga ccacgtgaac
    17221 cggcaagcgg acaagtttgc cctggttgat aatggctcgc tcgatatact gacgaatcca
    17281 ccaggacgcg tacgtactga agcggaatcc gcgcttgtaa ttgaacttct ctacagcctt
    17341 gatcaggccg agattacctt cttcgacgat gtcggcgaac gggaatccgc ggttcatgta
    17401 acgcttgccg atactgatga ccaggcggag attcgcttcg atcatctcct ggcgcgcggc
    17461 ttcatcaccg gccatgactc gcttgcccag cgcttgctct tgcttgaagt tcagcagggt
    17521 cgacttgcgg acctcgcgca ggtaactctt gatggtgtcg agaccttccg cacgcccgga
    17581 ttccgcctgg cggctttctc cgccggaatc ctccgactcg gcgaggcctg acgactccgc
    17641 atcctcatcc tcctccgccc gcgcagcacg cggacgtcgg gtcgagaccg gcgcacctac
    17701 ctcgctatcc tgtcgcacgg ttgcacgtcg agccataacg tcgtcaccta ctaccaaatc
    17761 gaaaaatcgt gatgccggcc cgtggcgttg ccccactcca cttgtacctg ggtcacacgc
    17821 gctccgaccg gccccttttt gagatcgacg agaaattcct caaggacggc ccgtccacct
    17881 tccacatcca ccgcgacttg tccgctatca agattttcca ctccaccggt caacccgcgc
    17941 gcagcggcca tgcggcaggt gaaggctcgg tagcccactc cctggacacg accactcacc
    18001 aggattcgcg cgcgcacaga ttcgccgatt tcggtcatcg tcagtacgtc ctcaatgcca
    18061 gggtgttggc gcagagcgat ttccccgcct agcacagaat actctcacag cgcctacagg
    18121 tcgtcacgcg atttgcaact ttacgcggct gtctcaggct catacgccta ccttatcggc
    18181 aggaccgtca caaaccatga gcgccatgac acacctcgcc ggtttgcggc cgaacgtcgt
    18241 cacgttcagc gcgactggag aggcacttgg tcgatggaac gctgcgagga attactaatt
    18301 ggagcgcttg gcccgaagaa ctgggaaaga aagtctgacg ggagaaggaa gtgctgtttg
    18361 gtcggggcga gaggatttga acctccgacc cctgcgtccc gaacgcagtg cgctaccggg
    18421 ctgcgctacg ccccgaccgg gcggaaccga aaaactgaag ccggattgtc ttacaacaga
    18481 ggggtaaaac gcaagccgtg agattcagcg accgcctggc acgtaatctt cccattcatg
    18541 acgttcacgc ctttggccag gccgggatcg gagtgaatgg ctttcccaac cccttccgat
    18601 gcgagacgga caagataggg aagggtcacg ttggtcaacg ctcgcgtgga agtgtgcggg
    18661 acaatccccg gcatgttggt cacgcaatag tgcacgacac catccaccgt atacacagga
    18721 tctgaatgcg tcgtgggcct ggtggtttcg cagcacccgc cctggtccac ggcgacgtcc
    18781 acaatgacgg ctccagcctg catcttcgac acgagactac gcgaaatcac gcggggtgca
    18841 cgcgcgcccg gcaccaacac ggctccaatc accaagtcag cctgcatgac cgctcgctca
    18901 atggccgatt cagtggcggc acaggtcgca atgcgtccgc cgtacaggtc atcgagcag
//
LOCUS       DAOQPD010000079        18824 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1476_length_18824_cov_20.633438, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000079 DAOQPD010000000
VERSION     DAOQPD010000079.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 18824)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 18824)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18824
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1476_length_18824_cov_20.633438"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            40..1005
                     /locus_tag="PK063_15190"
     CDS             40..1005
                     /locus_tag="PK063_15190"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008465 - glycerate dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycerate dehydrogenase"
                     /protein_id="HMZ98443.1"
                     /translation="MAAPTLYISRLLPDPVMTAARRQFQLLNDPRDASPSWDNVKTGL
                     READAAICTLTDRVDASMLAEATRLKILANYAVGYNNIDLAAAKARGIVVTNTPDVLT
                     DSTADLTWALLLAVTRRVAEGDAYVRSGDWSGWAPTQMLGTDVSGKTLGIVGMGRIGQ
                     AVAQRAAGFNMRILYTSRTPTALERVSSQWESRTLPDLLKEADFVSVHVPLTAATHHL
                     IGARQLALMKPTAFLINTSRGPVVEEAALVDALLQRRLAGAGLDVFEHEPAFHPSLRE
                     LRQVVLLPHLGSATLATRVRMGMICLENIAAVVAGKPAPNQVHAA"
     gene            complement(1061..>1584)
                     /locus_tag="PK063_15195"
     CDS             complement(1061..>1584)
                     /locus_tag="PK063_15195"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ98444.1"
                     /translation="PAPVVEVEPVIAAAPPPQAPPPVAPPAPVVEPVDAETRYALGMA
                     YKDMGLCEEAKEEFILSMKDSGFFVDSCLMMALCCKEQSRPDQAIQLLEKLISDSRCR
                     GGNAQLVRYELALLYEMTGARDRALTMYQSIPSFHDVPRRVEALRMQSTNGAAHPELP
                     ASTPTSPLPIAGH"
     assembly_gap    1585..1684
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<1685..3177)
                     /locus_tag="PK063_15200"
     CDS             complement(<1685..3177)
                     /locus_tag="PK063_15200"
                     /inference="COORDINATES: protein motif:HMM:NF024824.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ98445.1"
                     /translation="MAVDRRTVLQNAQLFASKGQYDAAIAEWRKLIADTPNDGTVFNS
                     IGDLQLKRNATAEAVTAFLQAASAFRSEGSVLKAIAAYKKILKVDPARIEIYRHLGDL
                     NAERGLLSSAVQDYLTLGKHYFKDGRNKEALEIYRKIVSQDPSNLDAQLRVAELCVQE
                     GLVDEAVRMYLQLGREQSAAQQYEQAKAMYTAVLRLDPENAEAKEITSMIETGGSVTP
                     SAARPAKPATTAAKPGDASDLMAEATRRIEEGQYAGAEAMLTQLLSREPGNPEICQLL
                     ARMHLLQGNLVVALGEYRFLAGAALRAQDYGVAESLIADYLKVEPASVPMLELLGELY
                     QEKGDAATAAQHFGRAVEILLEHPEPGMPTLPAELFEKVQALAPGSPIARKLAPAFDP
                     NAGSMPEPEPIAPVMEVVLTPAPEPVVEPAPELEPTPVIMAAAPPAEVPFRFVGDPAP
                     PLEAAVVKPPNVEPVVEPVVVQAAPPPEVPPAPVVEVEPVIAAAPPP"
     gene            complement(3357..3575)
                     /locus_tag="PK063_15205"
     CDS             complement(3357..3575)
                     /locus_tag="PK063_15205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HMZ98446.1"
                     /translation="MKTKGTVKWFNDRKGFGFIRLDGGDDVFVHYSALQGDGFKTLKE
                     GENVEFDIVQGAKGPQAANVLKDLAPAN"
     gene            3888..4973
                     /locus_tag="PK063_15210"
     CDS             3888..4973
                     /locus_tag="PK063_15210"
                     /inference="COORDINATES: protein motif:HMM:NF015684.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LptF/LptG family permease"
                     /protein_id="HMZ98447.1"
                     /translation="MLHTILDRYIFRELLSPFCISLGALCFVMLTKELLRLVELLVTK
                     GIGFLSVLKVFAHLLPSFLVLTLPIAGIIASITAFGRLSLDKELVAMRAAGFSLLRLS
                     QPVFLFAALVCGLTLMMAQYGQPWSNVNLKKVALNLLRDELVLELDRGVFNEAIPKMV
                     IYVPDAQEGQDNRGIFVADERNPADPRIIVAQQYQVMTDSASSQVALRLMNGVIHSRP
                     QNPEEYQKISFTAYDLKLSINASLYGAEERTPMDVIRAKLESSNWTDTNALRRLMEYY
                     KDLAFPAASLVFCILGVPVGIVSKRSGSIGGFAVGVLVVIAYYVINVACEFLVTTLWI
                     SPFAGAWLPNVIFTIVTILWFYRVSRQ"
     gene            4978..6069
                     /gene="lptG"
                     /locus_tag="PK063_15215"
     CDS             4978..6069
                     /gene="lptG"
                     /locus_tag="PK063_15215"
                     /EC_number="7.5.2.5"
                     /inference="COORDINATES: protein motif:HMM:TIGR04408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015920 - lipopolysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptG"
                     /protein_id="HMZ98448.1"
                     /translation="MNILFRYMLREYVKIFGMCFSGLMTIYLVIDFFEKVRRFLRYDA
                     HALDVLAYFVLKMPAISYQIAPLAVLMATLLTIGLLSRSHEITAMRSCGISLYWITSP
                     FIFLGTVLAMVLFLFSSTVIPLALAKADQIKTTQIEKRVTPVSLKAAQPWVSLGGQTL
                     LNIDTIDPGGAVLRNIRLYRLSPTFQLEEIAEAKSAVYSSQGWALHDGMTRSFRQDGT
                     VLVSSFQTQPLALPHIPDDFTTWAELDSETMTLREIRAYVDRLHLGGTMLPRLLTDYY
                     GRIAFPCVTLIMVIVGIALSLRRTGVRGSGMAMGIGQAMAVGFFYWSTHSVAIALGRG
                     GALSPMLAGWMANMVFLTFGLYLLMKVRY"
     gene            6322..7578
                     /gene="fabF"
                     /locus_tag="PK063_15220"
     CDS             6322..7578
                     /gene="fabF"
                     /locus_tag="PK063_15220"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: protein motif:HMM:NF005589.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HMZ98449.1"
                     /translation="MSTRVVITGLGVVSPIGIGVPQFWKAALEGRSGISAIPSFDPFP
                     LEGYRSRIAGRIVDFSPDQYLPAGQGDRVDRYAQFALVAAKEALADADFKMERENPHR
                     VGVIVGAGMGGMVMGEREITQLYEQKRPHRVHPNFIPVITLNSASGIVAMAYGAKGPN
                     LTISTACSSSAHALGQAMHAIRAGTADAVIVVGADASITPLVFAGFCSLRALSTKYND
                     APEKASRPFDRGRDGFVMGEGAGALILESLAHAKKRKARMYAEVAGYAATSEAHHMVI
                     PREDGEEVATTMRLALKDAGVTPAQVDYINAHATSTTVGDAVEVKAIRLVFKSRADKL
                     AVNATKSLVGHTLGAAGSLAGVVSALTLTSGQIHPTLNLDDPDPACALAGLSKDQQTR
                     KAKVALINAFGFGSNNAAVVLKAVSS"
     gene            7641..8000
                     /locus_tag="PK063_15225"
     CDS             7641..8000
                     /locus_tag="PK063_15225"
                     /inference="COORDINATES: protein motif:HMM:NF012759.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HMZ98450.1"
                     /translation="MATTTDVSSKIIQALAEYLKRDASSITPTHHLREDLGLDSMAVI
                     EMLYRIEEVFNLQIPDQDLVGLTTVGHVIAYVEGRVAPASTKTAAKGAAKPSAKTPAK
                     PAAKKPAAKPSPKSKKA"
     gene            8005..9087
                     /gene="lpxD"
                     /locus_tag="PK063_15230"
     CDS             8005..9087
                     /gene="lpxD"
                     /locus_tag="PK063_15230"
                     /EC_number="2.3.1.191"
                     /inference="COORDINATES: protein motif:HMM:NF002060.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016410 - N-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-(3-hydroxymyristoyl)glucosamine
                     N-acyltransferase"
                     /protein_id="HMZ98451.1"
                     /translation="MSTAPRRTPLTLRELHDYVGGELIGSPDATVTAVASLEQAGPGD
                     LAFVTSERHLKAPQTATFGALLVGRRIADCPSPQIVVENPAYAFARAAQQFFARPARV
                     RGIAECLTRGDGVTIGTDVSIWPGVTLGDRVTIGARVTLYPGVFIGDDTSIGDDSLLY
                     PNVVVREGCRIGARVIIHSGTVIGSDGFGYVQYQGRHQKIPQLGGVLIEDDVELGANV
                     SVDRATFGDTVIKRGTKIDNLVQIAHNVVVGEHNILVAQVGIAGSTTLGRYVMVGGQA
                     GLADHLQIGDQVMIAAKSGVTRSLEPNQIVSGAPVMAHATFLKAQAVIPQLPELRNRV
                     RELEERLATLEQAAKPAAKTRKPRRK"
     gene            complement(9105..9629)
                     /locus_tag="PK063_15235"
     CDS             complement(9105..9629)
                     /locus_tag="PK063_15235"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98452.1"
                     /translation="MPKLVSVKQQEGHDARATAYIKAYMLFPAGILGLISMLGGVGGL
                     AYQLIATDTYSWTTFVESSGLLLLGGLLGWVQTTYHRWILANRPEVFAERMRQPALTK
                     SGKPKRESGKNQESSSGSPWAPGAYMVGLAVLLAGSMLSMLYGAVHPIPACFLPWAGF
                     FWAKLFFWKTLLKP"
     gene            complement(9882..11969)
                     /locus_tag="PK063_15240"
     CDS             complement(9882..11969)
                     /locus_tag="PK063_15240"
                     /inference="COORDINATES: protein motif:HMM:NF014069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HMZ98453.1"
                     /translation="MEQNHYRHAEEILTKVAASVQRQEDVDLTELTHLADSIVESLQG
                     SDQLVVEALSSPSGPPLVTNLINVGILATKVGIGLGYYGVELHRLAVAGLLHDIGIFA
                     VPQQLLTKAGRLTAEERTLVEQHPRLGSEVIRRVGTEYGWLAEVVLQAHERGKGQGYP
                     HRLKGREINELAQIIGLVDIFDALVSPRPYRRRLLPHEAVRELLTTERTAFPREIMKA
                     LVEQLSVYPLGTRVRLSSGQEGVVVRITARYPSRPVLRITSTETAAPSEPPHLLDLSL
                     LPHVSVVDTVEPPALDRVTFEAAGAAPTASAAPTNVSDQFAALLESLDAIAGVIQAAV
                     DQPAVARGPAQVPAEAETAEPLIPVRREILGLFVLEAREWLNQIQTALERLDATSEQA
                     RRAQLASILWQSVNNLARSAATVGLTAVETMATRLFPLLQAAARHERAVAAHHVASLR
                     EGLLEISKTVQELRPIEEHPAPAEETVEREQPILEQPARTELPESQASSEPASEIATP
                     RYAPPRPMPASSILDALRQLHVARGRSLEPVRDVLETVIQRAERELAQGAPVVDARAI
                     GRLLQELDELDERFLNHMQARVPSVVSTLGRIARASEERVLPPQALEPIFEEIDVLFE
                     ASEKVSAENISVFLQGLRTFLRVTAQHKPAVIRERLAAVEERLATLIPLAQQWVDVGR
                     VERAAIFDILPMA"
     gene            complement(12152..13099)
                     /locus_tag="PK063_15245"
     CDS             complement(12152..13099)
                     /locus_tag="PK063_15245"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98454.1"
                     /translation="MSTEPEQTQDDFQKELIELFGQEAQEWLVQIHAALVELESLPDS
                     DRHSQLIDAVVRGITSLGGSAATVSLPDVERATFALLPFIETIKDRTTATKQDFSTVR
                     EHFRTVIASVKVATGITLDIDPLPEAAPAPEPVLEFLPLLNALHQLQDEQAAQGSMSR
                     SLIPQVLQRLEHEARIGAGQITAAQFQELLLTIHNTDAQYLGSLRQDLPGIALHLSRL
                     RAGGVAVLTSDAGFDAPIQMIASLHEIAKQTNATPLVTFLTGLQNFLTLVVQRRIDIA
                     AHRLQSVETRILAVASMVEEWIADGQKEFDMMSRLAPST"
     gene            complement(13156..14631)
                     /locus_tag="PK063_15250"
     CDS             complement(13156..14631)
                     /locus_tag="PK063_15250"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ98455.1"
                     /translation="MPKILIADDSIAVRKVAERLLTEAGMGVTLAANGSEALAMLAKD
                     RPDLIVSDVIMPDKSGYEVCAFIRGQANLADLPVLLISGIVNDEVSKQAESCKADGVL
                     KKPFQGSSLKDRVLDLLTKRPHKPAPVAEPIRIPIAEPPVMAEVAPAPVAPAQEELPS
                     IPLVQREWQQPAEPVAIVLDQTPAGPVGIEESRAGSISIHQAAEPSPVMQADDRHQAL
                     LADRDAKIAELEAQLGAERRHSQEEREQHQLTVSEQREQMADVSSRMQALEQDLAKER
                     AQRESMTQQLEDLSRQAHRLGEVEAALLEERHRADQLAQQAAESARLGARIVELEAHL
                     EAEREAANQLVNQITSLEHVEDRMRELERVLASEREEAMALRNERAHLEKSAAMVPVL
                     EEAGEHARAQVAELERTLTAEREAAAALLAQYKQMEEKAQLVPDLEQELSAERDHSMQ
                     LTKQVADAESMAEQSTRRFEDLARKLGEIAGLASQLGNAKR"
     gene            complement(14660..15136)
                     /locus_tag="PK063_15255"
     CDS             complement(14660..15136)
                     /locus_tag="PK063_15255"
                     /inference="COORDINATES: protein motif:HMM:NF013731.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HMZ98456.1"
                     /translation="MLRSQLRRHPHTTASGAAHARVQNMVVFSVAGKRLAARTEEIGG
                     VLPWPGTTAVPSDTPLVTSLVRHEESCLPVFDLAAKFNRTVREEESLCLIVKHVDGPL
                     AICIDSQVPSLHVVPRSGVQYQSGLDPDIAGSCVAGDEQLPLINLATLGVASQRPA"
     gene            complement(15152..15724)
                     /locus_tag="PK063_15260"
     CDS             complement(15152..15724)
                     /locus_tag="PK063_15260"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98457.1"
                     /translation="MGLRGQRAVTISSGQAVRFLVTLIGGSSVAFPAQWVRGIVMPAS
                     AGPNGLVTWAGVEYERTDLSARLKVVSKGVSSDTRLILYGNDERSRSFAVDKVVGLLD
                     VERALIHPLPPQFRGKERERLLGFFVGASFVALIANPLWVLELPLRAQTLEMFAIRFA
                     ESKAGESDSRLHVPMVGVDEAMSMSTSPVS"
     gene            complement(15772..>17012)
                     /locus_tag="PK063_15265"
     CDS             complement(15772..>17012)
                     /locus_tag="PK063_15265"
                     /inference="COORDINATES: protein motif:HMM:NF013731.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ98458.1"
                     /translation="RVQGKPETGTIYLHAAHRGNSVLIEVEDDGAGLDIAKIKAKAVK
                     LGLVRQDVAETLPESEVIKFIFLPGFSTADAVGDQAGRGVGMDVVKRVIETMNGHIEV
                     ESVRGQGTKFTMHLPLTLLIATALLVRVGKDRYAIPLPSVREVTMSTASTLQHMGDRQ
                     VVQIGDEAIEVYPLGSLIRREAGITDGVSPVVIVRTSTGALGCAVDELLGRQEIVIKS
                     LGGLKPYERSVFGGATIDPEGRVVLVLDVSRLTTREYQETMSIAQDSSVAAIEDATGH
                     SEPKASAPSALPLLLIDDSLSIRKFVGRMLEAAGYTVETATDGEEGCRKAMVQAYQLI
                     ITDLEMPKLNGYEVIQALRARPQTHATPILVMTTRAGEKHRQMAVSVGASGYIAKPVE
                     ERALIQEVRKWTGVEARAEK"
     assembly_gap    17013..17112
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<17113..>18824)
                     /locus_tag="PK063_15270"
     CDS             complement(<17113..>18824)
                     /locus_tag="PK063_15270"
                     /inference="COORDINATES: protein motif:HMM:NF013767.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hpt domain-containing protein"
                     /protein_id="HMZ98459.1"
                     /translation="SYFAPEAEEYLNTIQTLLQRLELDLSDAETIHQLYRVAHTLKGS
                     AYTVGFQVVGDVAFPIETCMIAVREGAAVIGPQWIATIRHAVDVMRSLMARDAQQLPR
                     LRQDVPCMTTMLRELEQGMTQAPQVDAPAASSSSVAAEEALPPAAKPLNPAAQLSEPN
                     HPAELSEAYLIPMLDAEVISYFAPEAQEYLESLETDLLRVDKDAANPDIIHQLFRTAH
                     TLKGSAYTVGFQSIGDLTHHIEDFMGAVREGRLKFLPGHTDVLLRAIDVIRALMRRDP
                     SLVTRTRQRFAASLQELKGLGEAAPAGVHEPVMSSQTEAVIALDVQEAEQAEPVNAAE
                     GKAGEEREVIRVSRDRLERLLNLVGELVIDRGRLEQRLRTLDQLATQVLANKNRLTDA
                     VRTFEDKHTFSFQPSPTTQGEAMPQGFPGVSDFGSLEFDKYDDFNILARRISEVTADI
                     SESMSQLSGSIHRAQDDMGSLQQLTLGMRDEIARARMVPIGTPFTRFRRAAREMARAT
                     GKDVNLVTSGEHTEIDTGVVERLVDPLVHLVRNAVYHGIEPAAVRRVQGKPETGTIYL
                     HAAHR"
BASE COUNT         3614 a         5761 c         5463 g         3786 t
ORIGIN      
        1 gcgatccgct aagatgctcg tcagtccggc gaggcgttca tggctgcccc taccttatat
       61 atctcccgtc tgctcccgga tccggtgatg acggccgccc ggcggcaatt ccaactgctg
      121 aacgatcctc gtgatgcctc gccctcttgg gacaatgtga aaacaggcct acgtgaggcc
      181 gacgccgcga tctgcacgct caccgaccgc gtggatgcct ccatgctggc cgaggcgacg
      241 cgtctcaaaa tcctggcgaa ttatgccgtg ggctacaaca acatcgatct cgctgccgcg
      301 aaggcgcgcg gcattgtggt gaccaacaca ccggatgtgt tgaccgactc tacggcggat
      361 ctgacctggg cgttgcttct ggcggtgact cgacgggtgg cggagggcga tgcctacgtc
      421 cgatccggag attggtccgg ctgggcgccg acgcagatgc tgggcacgga cgtatcggga
      481 aaaaccttgg gcatcgtcgg gatgggacgc atcgggcagg ccgtggcgca gcgggccgcc
      541 ggtttcaaca tgcgtatcct gtatacctca cgcaccccga cggctctcga acgagtgtcg
      601 tctcaatggg aatcccgcac cctccccgat ctgctgaagg aagccgattt tgtgagtgtg
      661 catgtgccgc tgactgccgc cacccatcac ctgatcggtg cccgccaact cgcgctgatg
      721 aaaccgaccg cgttcctgat caatacatca cgtgggccgg tggtcgagga ggccgcgctg
      781 gttgatgcgc tccttcagcg caggctggcc ggtgcggggc tcgatgtctt cgagcatgaa
      841 ccggcctttc atccgagcct gcgcgaactc aggcaggtcg tgctgctgcc ccatttggga
      901 tccgccactc tggccaccag ggtccgcatg ggcatgatct gtctggaaaa catcgcggca
      961 gtggttgcgg gaaagccggc gccgaatcag gtccacgccg cctaacacag ctccacgccg
     1021 tgacgctcga gacgagagca agactgtaga aggactggcc ttagtggccc gcgatgggca
     1081 gaggactggt cggagtggat gcgggaagtt ccggatgcgc ggccccgttg gtcgactgca
     1141 tccgcagcgc ttcaacccgg cgaggcacgt cgtggaacga cggaatggac tgatacatgg
     1201 tgagcgcccg atcgcgagcg cccgtcatct cgtagagtaa cgcgagttcg taccggacca
     1261 attgcgcgtt gcctccgcgg cagcgcgagt cagagatcag tttctccaac aactgaatgg
     1321 cctgatccgg acggctctgc tccttgcagc agagggccat catcaggcag gagtccacaa
     1381 agaatccgga atccttcatc gagaggatga actcttcctt cgcttcctcg cagagcccca
     1441 tgtctttgta ggccatgccc agggcataac gcgtttccgc atccaccggc tccactacgg
     1501 gtgcaggcgg tgccaccggc ggtggcgcct ggggaggagg cgcggcggca atgaccggtt
     1561 caacttcgac gacaggtgcg ggagnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1681 nnnntgggga ggaggcgcgg cggcaatgac cggttcaact tcgacgacag gtgcgggagg
     1741 cacctcaggc ggcggagcag cctgtacgac gaccggctcg accacgggtt cgacattcgg
     1801 cggtttcacg actgcagctt cgagcggcgg cgcagggtca ccgacaaatc taaacggcac
     1861 ctcggcgggt ggtgctgcgg ccatgatcac cggcgtcggt tccaattctg gcgccggctc
     1921 gacaacaggc tcaggcgccg gcgttaggac gacttccatc accggcgcaa tgggttccgg
     1981 ttccggcatc gacccggcat taggatcgaa cgcaggcgcg agcttccggg ctatcgggct
     2041 ccctggcgcc agggcctgca ctttttcgaa gagctcagcc ggcaaggtcg gcatgcccgg
     2101 ctcgggatgc tccaacaaaa tctccacggc ccggccgaaa tgctgcgccg ccgtggcagc
     2161 atcacccttc tcctgataga gctcgcccag tagttccaac atggggacgg aggccggttc
     2221 cactttgaga tagtctgcaa tcaacgactc ggccacgcca tagtcctgcg cgcgcaaggc
     2281 cgcaccggcc agaaatcgat attcgcccag ggccacgacc agattaccct gtaagagatg
     2341 catccgggcc agtaattggc agatctccgg attgccgggt tcgcggctca gcaattgggt
     2401 caacatggcc tcggcgccgg catactgccc ttcttcgata cggcgcgtgg cttcagccat
     2461 gagatcgctc gcatcgccgg gcttggctgc ggtggtagcc ggtttggccg ggcgtgccgc
     2521 actgggcgtc acactgccgc cggtttcgat catcgacgtg atttctttgg cctcggcatt
     2581 ctccggatcc aggcgcagca ccgccgtata catcgctttc gcctgctcgt actgttgcgc
     2641 ggccgactgc tcgcggccaa gttgcagata catccgcacc gcctcgtcga cgagcccttc
     2701 ctgcacacag agctccgcga cgcgtaactg ggcgtccaga ttagacggat cctgggagac
     2761 gatcttgcgg taaatctcga gcgcttcttt gttccggccg tccttgaagt aatgtttgcc
     2821 cagcgtgaga tagtcctgta cggcgctgct cagcagcccc cgttcggcat tcagatcacc
     2881 gagatggcga tagatttcga tccgggccgg atcgaccttg agtattttct tataggcggc
     2941 gatagccttg aggacggaac cttcggagcg gaatgcgctg gcggcttgca gaaacgccgt
     3001 gacggcctcg gcggtggcgt tgcgcttgag ttgaagatcg ccgatggagt taaacaccgt
     3061 gccgtcgtta ggcgtgtcgg cgatcagttt ccgccattcg gcaatggcgg catcgtactg
     3121 ccctttggac gcaaagagct gcgcgttctg tagcactgta cggcggtcga cagccaagga
     3181 gacccctcac ccgacgttga gagtccacgc taacagtcaa cctatttatt gtcaaaacaa
     3241 atggataaaa gagagacacc gcacacgcgg cgtccggagc ggggattctc tgaaggaaac
     3301 cggcggcccc tcgatgaggc agaggggccg cggattacgt atgactccgg ccgaaattag
     3361 ttggccggcg cgagatcctt caacacgttg gccgcctgcg gtcccttggc gccctgaacg
     3421 atgtcgaact ccacgttctc gccctctttc aaggtcttga acccgtcgcc ctgcagcgca
     3481 gagtaatgca cgaagacgtc gtctccgcca tcgagccgga taaatccgaa tcccttacga
     3541 tcgttgaacc acttcacggt gcccttagtc ttcatacggt cctccttttc tcaacgcacg
     3601 gacataatga gcgcatcagc tcgtctgctg agtcgcatga taggaaatga tgacgataaa
     3661 aaaggagaaa caacagcgac gagcgcggcg gcttttgcgg gggcgttcag acaatattca
     3721 acccgaacca tcttaacctg ctgaaaagtg cgcagcgatg taccatgggg tgaaatgctt
     3781 gtcaagcgga tctttatggc cctggcctat ctgatctgtt tacaaggcac gcagactctt
     3841 ctatagtgca gcatccaatt ctccgatgta ggaccccgac cgctctcgtg ctgcacacca
     3901 tcctcgatcg ttacatcttc cgcgagttgc tttcgccgtt ttgcatcagc ttaggcgcgc
     3961 tgtgcttcgt gatgctcacg aaggaactgc tccgcctggt ggagctgctg gtgacgaagg
     4021 gcatcggctt tctgtcggtg ttaaaagtct tcgcccactt actcccctcg ttcctcgtgc
     4081 tcaccctgcc catcgccggc atcattgcct cgattacggc cttcggccgg ctctcgctgg
     4141 ataaagaact cgtcgccatg cgcgcggccg gcttcagcct gttgcggctc tcccagccgg
     4201 tgtttttgtt tgcggcgctc gtctgcggcc tcacgctcat gatggcgcaa tacgggcagc
     4261 cgtggagcaa tgtcaatctc aagaaagtcg cgctgaacct gttacgcgac gaactggtgt
     4321 tggagctcga ccgcggcgtg ttcaacgaag cgatccctaa gatggtgatc tacgtaccgg
     4381 atgctcagga ggggcaggac aaccggggca ttttcgtggc ggatgaacgg aacccggctg
     4441 atccgcgcat catcgtggcg cagcagtacc aggtgatgac cgactcggca agcagccagg
     4501 tggcgctgcg cctcatgaac ggcgtcatcc acagccgtcc gcaaaacccc gaggagtatc
     4561 agaagatttc gtttacggcc tacgatctca aattgagcat caacgccagc ctgtacggag
     4621 ccgaagagcg cacgccgatg gacgtgattc gcgcgaaact ggaaagttcc aactggacgg
     4681 acaccaatgc cttgcggcgg ctcatggaat attataaaga cctggcgttt ccggccgcgt
     4741 cgctggtgtt ctgcatcctg ggcgtgccgg tcgggatcgt gtcgaaacgc tccggcagca
     4801 tcggcgggtt tgccgtcggc gtgctcgtcg tcatcgccta ctacgtcatc aatgtcgcct
     4861 gcgagtttct cgtcaccacg ctgtggatct ccccgttcgc cggcgcatgg ttacccaatg
     4921 tcatcttcac gatcgtgacg attttgtggt tttatcgcgt gagccggcag taaccccatg
     4981 aacattcttt ttcgatacat gctgcgcgag tacgtgaaga ttttcggcat gtgcttttcg
     5041 gggctcatga cgatttatct cgtcatcgac ttttttgaaa aggtgcgccg cttcctccgg
     5101 tatgacgcgc atgcgctcga tgtgctggcc tacttcgtcc tgaagatgcc ggccatctcc
     5161 tatcagattg ctccgctggc ggtcttgatg gcgaccctct tgaccatcgg cctgctgtcg
     5221 cgcagccacg aaattacggc catgcgcagc tgcggcatca gcctgtactg gatcacctcg
     5281 ccgtttattt ttctcggaac ggtcctggcg atggtgttgt tcctgttcag ttccaccgtc
     5341 attcccctgg ccctggcgaa ggccgaccag atcaaaacga cacagatcga gaagcgcgtc
     5401 acgcccgtct ccttgaaggc ggcgcagcca tgggtcagtc tggggggaca gaccctgttg
     5461 aacatcgaca ccatcgatcc cggaggcgcg gtgttgcgca acatccggct ctatcgcttg
     5521 agtccgacct ttcaattgga ggaaatcgcg gaagccaaga gtgcggtcta ttcctcgcag
     5581 ggatgggcct tgcatgacgg catgacgcgt tcattccgcc aggacggcac ggtgctggtg
     5641 agcagctttc agacgcaacc gctggcgctg ccccacattc ccgacgactt taccacctgg
     5701 gccgaactgg actcggaaac gatgaccttg cgcgagattc gcgcctacgt cgatcgcctc
     5761 catctgggcg gcaccatgct cccccgcttg ttgacggatt attatggccg gatcgccttc
     5821 ccctgcgtga cgctgatcat ggtgatcgtc ggcattgcct tgagccttcg ccgcacgggt
     5881 gtccgcggaa gcggcatggc gatgggcatc ggacaagcga tggcggtcgg gttcttctat
     5941 tggtccacgc actccgtggc cattgcgctg gggcgcggcg gtgcgttgtc tccgatgctg
     6001 gccggatgga tggcgaatat ggtgtttctg acgttcggtt tgtatctgct catgaaggtg
     6061 cgctactaaa aggatgttga acgtgtccgc cagcgtcgtt ctcggatcat acgaaccatc
     6121 gatctaattg gctggaacgc ctgcgggcct tcacgtgctg cagtcttgct ggcgccaatt
     6181 tgagcctcct gtgcggtggt tccaccacga tacctacgga gatctcgagc gggtgcctgc
     6241 gtacagcatt gactgtgacg cccccgtgcg gtaagtagac aggccgcaca cctcaccatc
     6301 ctgcggccat gaaagggttt tatgtcgacg agggtcgtca ttacagggct gggagtcgtc
     6361 tcccccatcg gcatcggcgt gccgcaattc tggaaagcgg cactggaagg ccgatcgggg
     6421 atttccgcca ttccctcctt cgatcccttt ccccttgaag gctatcggtc gcgcatcgcg
     6481 gggcgcatcg tcgacttctc cccggaccag tatctccctg ccggacaggg cgatcgtgtg
     6541 gatcgatatg cgcaatttgc gctcgtggcc gctaaggaag cgctcgctga tgcggacttc
     6601 aagatggaac gtgaaaaccc gcaccgggtg ggtgtgatcg tcggagccgg catgggcggg
     6661 atggtgatgg gcgaacgtga gatcacacaa ctctatgaac agaagcgccc gcatcgggtg
     6721 catccgaact ttatcccggt gatcacactg aattccgcct ccggcatcgt ggccatggcc
     6781 tatggagcca agggccccaa cctcacgatt tccactgcct gctcatcgag tgcccacgcg
     6841 ttgggacagg ccatgcacgc cattcgcgcc ggcacggccg acgccgtgat cgtcgtcgga
     6901 gccgatgcca gcattacgcc tctcgtcttc gcaggatttt gctcgcttcg agccctctcc
     6961 acgaagtata acgatgcccc ggagaaagcc tcgcgcccct ttgaccgtgg acgggacggg
     7021 ttcgtgatgg gggaaggcgc cggcgccctg atcctcgaat cattggccca tgcgaagaaa
     7081 cgcaaggccc ggatgtacgc ggaagtagcc ggatatgccg ccacgagcga ggcccatcac
     7141 atggtcatcc cccgggagga cggcgaggag gtcgccacga ccatgcggct ggccctcaag
     7201 gatgcgggcg tgacgccggc gcaggtggac tatatcaacg cgcacgccac gtcgaccacg
     7261 gtcggcgacg ccgtggaggt taaggccatt cgcttagtat tcaagtcacg cgcggataaa
     7321 ctcgccgtga acgccacgaa gtctctggtg ggccacacac tcggcgcggc cgggtcgctg
     7381 gccggagtgg tctccgccct cacgctcacg agcgggcaga ttcatcccac gctcaacctg
     7441 gacgatcccg acccggcatg cgcactggcc ggcctgtcga aggatcagca aacacgcaag
     7501 gcgaaagtgg cgctgatcaa cgcatttgga ttcggcagca acaacgcggc cgtcgtttta
     7561 aaagctgtct cctcctgacg cctgtccgac agggcagcat tgacggtcga cgaaccagac
     7621 acgacacgaa gggaccgggc atggccacta ccacagacgt ttccagcaag atcattcagg
     7681 cgttggcaga gtatctgaag cgggatgcat cctcgattac gccgacgcat cacttgcggg
     7741 aagatcttgg cctggactcg atggcggtca ttgaaatgct gtatcgcatc gaagaagtgt
     7801 tcaacctgca gatccccgac caggatctgg tcggcctcac caccgtcggc catgtcatcg
     7861 cctacgtgga aggacgcgtg gcaccggcct cgacaaagac cgctgccaag ggcgctgcga
     7921 agccctctgc aaagactccg gccaagcccg ctgccaagaa gcctgccgcg aaaccttcgc
     7981 ccaagagtaa gaaagcctaa cagaatgagc acggcaccca ggcgcacccc gctgacactt
     8041 cgggaactgc acgactatgt aggaggcgaa ctgatcggtt ctccggacgc gaccgtcacc
     8101 gccgtagcca gcctggagca ggcaggacca ggcgatctcg cctttgtcac atccgagcgc
     8161 catctcaagg ctccacagac cgccactttc ggcgcgctat tggtcggacg gcgcatcgcg
     8221 gattgcccct ccccgcaaat tgtggtggag aaccccgcct acgcctttgc gcgtgcggct
     8281 caacagtttt tcgcgcgacc cgcccgagtg cgtggcatcg cggagtgcct cacacgcggt
     8341 gacggcgtca cgatcgggac cgatgtttcc atttggcctg gcgtcacctt aggcgaccgg
     8401 gtgaccatcg gcgcgcgagt gaccctgtat cccggagtct ttatcgggga cgacaccagc
     8461 atcggcgacg acagcctcct ctacccgaat gtggtcgtcc gggaaggatg ccggatcggc
     8521 gcccgcgtca tcattcacag cggcacggtg atcggcagcg acggcttcgg gtatgtccaa
     8581 taccagggcc gacaccagaa aatccctcag ctgggcggcg tgctgatcga agacgacgtg
     8641 gaattgggtg ccaatgtctc ggtggatcgc gcgacgtttg gagacactgt catcaaacgc
     8701 gggaccaaga tcgacaacct cgtgcagatc gctcacaacg tggtggtcgg cgaacacaac
     8761 attttagtgg cacaggtcgg tattgcgggc agcaccaccc tcggacggta cgtgatggtg
     8821 ggcggtcagg cgggcctcgc cgatcatttg cagatcggcg atcaggtcat gatcgcggca
     8881 aaatccggcg tgaccagaag tttggagccg aatcagatcg tctccggcgc accggtgatg
     8941 gcccacgcca catttctaaa agcccaggcg gtcattcctc agctgccgga actgcgcaac
     9001 cgggtccgcg aactcgagga acgtctcgca actctggagc aagccgccaa gcccgccgcc
     9061 aaaacccgca agcctcgccg taagtagctc gcacaccgat atcgtcaggg tttgagcagc
     9121 gtcttccaga aaaacagctt ggcccagaag aatccggccc acggcaggaa gcacgccgga
     9181 atgggatgga ctgcgccata gagcatgctg agcatcgatc cggcaagcag gaccgccagg
     9241 ccgaccatgt aggcacctgg agcccatggc gagccactgg atgactcctg attcttcccg
     9301 ctctcccgtt taggtttccc gcttttcgtg agcgcgggct gccgcatgcg ctcggcaaag
     9361 acctcaggac gattggccag aatccagcga tggtacgtgg tctgcaccca ccccaagagc
     9421 ccgcccagca gcaacaagcc tgagctttcg acaaaggtgg tccacgaata ggtgtccgtt
     9481 gcgatgagtt ggtacgccag cccgccgacg ccgccgagca tggaaatcag gccgagaatg
     9541 ccggccggaa agagcatgta cgctttgata taggccgtcg cgcgcgcgtc gtgcccttcc
     9601 tgttgtttga cggagacaag ttttggcatg gccgtgatgg tcgtataatc cccacctcaa
     9661 ccgcaagaga aattgtacag attgacgaga tatgttttgt gtgcgcccca cgtgagcggc
     9721 atcacacggc ctgtccacaa gaactgtgga cggactgtgc gcaaccatgt ggatggaacg
     9781 cttttcgtcg gactacgagg gggcgcagat caactgccta aggattaggc gggcagaatc
     9841 ggtgagcaga gagaaccagg gtccgtcagt ggaccacgac gctaggccat cggcagaata
     9901 tcaaaaatgg ccgcccgttc gacccggccg acatccaccc attgctgggc caacggaata
     9961 agcgtcgcca agcgctcttc cactgcagcc agccgctcgc gaataacggc cggcttatgt
    10021 tgcgcggtca ccctgagaaa tgttcgcaga ccttgcagaa agacactgat attttccgcg
    10081 gaaacctttt cggacgcctc gaacagcaca tcaatttctt caaaaatcgg ctcgagagcc
    10141 tgagggggca acacgcgttc ttcgctcgcc cgagcaatac ggccgagcgt cgagaccact
    10201 gaaggaaccc gagcctgcat gtgattgaga aatcgttcat ccaactcatc caattcctgc
    10261 agcaggcgac cgatggcccg tgcatccacc acgggcgcgc cctgagccag ctcgcgttcg
    10321 gctcgttgaa tgaccgtctc caacacatcg cgcactggct ccagcgagcg tccgcgtgcg
    10381 acatgcaatt gtcgcaaggc atcgagaatg gatgacgccg gcatggggcg cggaggagcg
    10441 taccggggcg tagcgatttc agaggcgggt tcgctggagg cctgcgactc cggcaactcc
    10501 gtccgcgccg gttgttcaag gatcggctgt tctcgctcaa cagtctcctc ggctggcgca
    10561 ggatgttctt caatcggtcg aagctcctgt accgtcttgc tgatctccag caacccttct
    10621 cgaagggatg ccacgtgatg cgcggcaacg gcccgttcat gcctggcagc cgcctgcagg
    10681 agtggaaaga gcctggtcgc catcgtttcc acggccgtca atccgaccgt ggccgcggaa
    10741 cgggcgaggt tgttcacgct ttgccataaa atggaggcca attgtgcgcg gcgcgcctgc
    10801 tcactggtgg catccagacg ttccagcgcc gtttgaatct gattgagcca ttcccgcgct
    10861 tcaaggacga acaggcctaa gatttcccgg cgtacaggga tcaacggttc tgccgtctcc
    10921 gcctcagccg gtacctgggc cggtcccctg gctacggctg gctggtccac ggcagcctgg
    10981 atgaccccgg caatggcgtc gagactttcc agcagggccg caaattggtc tgagacgttt
    11041 gttggcgcag cagatgctgt tggtgcagcc ccggccgctt cgaatgtgac acgatccaac
    11101 gccggcggct cgacggtatc caccactgac acatggggca agagactcaa atcaagcagg
    11161 tgcgggggtt ctgaaggcgc cgcagtctct gtgctcgtga tgcgcaagac cggccgcgag
    11221 gggtaccggg ccgtgattcg taccaccacc ccttcttgtc cgctgctgag ccgcaccctc
    11281 gtgccgagtg gatacaccga caactgttcg accaacgctt tcatgatttc ccggggaaac
    11341 gccgtgcgtt ccgtcgtcag caattcgcgc acggcttcgt gcggcagcaa tcgtcgccga
    11401 tagggacgtg gactcaccag ggcatcaaag atgtccacca agccgatgat ttgtgccagc
    11461 tcgttgatct ctcgaccttt caagcgatgg ggatacccct gccctttccc ccgctcatgc
    11521 gcttgcagca cgacttctgc caaccatcca tactccgtcc ccacacgtct gatgacttcg
    11581 gaaccgagac gtggatgttg ctcgaccaac gtccgttctt cggctgtcag gcgcccggcc
    11641 ttcgtgagga gctgctgcgg tacggcgaaa attccgatgt cgtgcagcaa tccggctacg
    11701 gcgaggcggt gtaactcgac accgtagtac ccaagaccga tcccaacctt tgtcgccaga
    11761 atgccgacat tgatgaggtt ggtgactagc ggaggcccgc tgggactgga gagcgcttcc
    11821 acgaccagtt gatcgctgcc ctgtaacgat tcgacgatac tgtctgcgag atgcgtgagc
    11881 tcggtgagat ctacgtcttc ctgccgttgg acggaggcag ccaccttcgt caggatctcc
    11941 tctgcgtgcc ggtagtggtt ctgttccata cttctttctt caactccccg ccttggctgg
    12001 ctaaatgtgg ccgtcgggag tcgcaatcgc gacggatctc actcgaatag attcagagtc
    12061 attgtgacat cgagcctgtg gtgagcatga tcgccgattc aaccggtccg ctgcggaagg
    12121 tttgcgacgg cctgccggtc gcttcgcacc gttaggtcga gggggcgagc cggctcatca
    12181 tgtcgaactc tttttgcccg tccgcaatcc actcttcgac catgctggcg acggccagaa
    12241 tgcgggtctc gaccgattgg agccgatgag ccgcaatatc gatgcggcgt tggacgacca
    12301 atgtgaggaa attctgcagg ccggtcagga acgtgacgag cggcgtggca ttcgtctgct
    12361 tggcaatctc gtgaagactt gcaatcatct gtattggagc atcgaaaccg gcatcggagg
    12421 tcaggacggc aaccccgccg gctcggagcc ggctgaggtg cagcgcaatg ccaggcaagt
    12481 cctggcggag cgacccgaga tattgggcgt cggtattgtg aatcgtcagt aacagctcct
    12541 gaaactgtgc agcggtaatc tggccagcgc ctatacgcgc ttcgtgttcc aaacgctgca
    12601 gcacctgcgg gatgaggctg cgggacatgc tgccttgcgc ggcctgttca tcctgcagct
    12661 ggtgcagtgc attcaacagg ggaagaaact ccaacaccgg ttcaggcgcc ggcgccgcct
    12721 ccggcaaggg atcaatgtcg agcgtgattc cggtggccac tttcacggac gcgatgacgg
    12781 tccgaaaatg ttctcggacc gtgctgaagt cctgtttggt tgcggtggtc cggtctttga
    12841 tcgtctcaat gaacggaagg agggcaaacg tggcgcgttc gacatcgggc agactcaccg
    12901 tggcagctga gccgccgagg ctggtaatgc cccgcactac cgcgtcgatt aattgggaat
    12961 gccgatccga atccggcagg ctctcgagtt cgaccagggc cgcgtggatc tgcacaagcc
    13021 actcctgcgc ctcctgcccg aacagctcaa tgagctcttt ctggaaatcg tcttgggttt
    13081 gctctggttc cgtcgacacc gtggatcctg cctctgacgc atgcacccgc ctgctaccgg
    13141 acgagtgacg gcctcttagc gtttggcatt tccgagttgg gaagcgaggc ctgcgatttc
    13201 gcccagtttt cgcgccagat cttcaaatcg tcgcgtagac tgttcagcca tcgattcggc
    13261 atcagcgact tgttttgtga gttgcatgga gtggtcccgc tcggcactca gctcctgctc
    13321 caagtccggc accagctgag ccttctcttc catctgcttg tattgcgcca gaagcgcagc
    13381 tgcagcctca cgttcagcgg tgagtgttct ttcaagttct gcaacctgag cgcgagcgtg
    13441 ttcacccgcc tcttccaata ccggcaccat ggccgcactc ttttccaaat gcgcccgttc
    13501 gttccgcaga gccatcgcct cttcccgctc gctcgccagc acccgctcga gctcccgcat
    13561 gcggtcttcc acgtgctcaa ggctggtaat ctgattgacc agttgattgg ccgcttcacg
    13621 ctcggcttcg agatgcgctt ccaactcaac gatgcgcgca ccaagacggg cgctctccgc
    13681 cgcttgctgc gccagctggt cggcgcgatg ccgttcttcg agcaacgcgg cttccacctc
    13741 acccaaccga tgcgcctgcc tggacagatc ttccagctgt tgcgtcatcg actcccgttg
    13801 ggctcgctct tttgcaaggt cctgctcgag ggcttgcatc cgggaggaca catccgccat
    13861 ctgttcgcgt tgctccgaca ctgtcagctg atgctgctct cgctcctcct gactgtgtcg
    13921 acgctccgct cccagctgtg cttccagttc ggcaattttg gcatcccgat cggccagcag
    13981 cgcctggtgc cgatcatcag cctgcatcac agggctcggc tcagcagcct gatggattga
    14041 aatgctcccc gcgcgacttt cctcgatccc tacaggtccg gccggcgttt ggtccagaac
    14101 gatggccacc ggttcagccg gctgttgcca ctcacgctgg actaacggga ttgacggaag
    14161 ctcttcctgc gcaggtgcga cgggcgctgg cgcaacctca gccatgaccg gaggctccgc
    14221 aatcggaatg cgaatcggtt cagccaccgg ggccggcttg tgcggtcgct tggtcagcaa
    14281 atccaacacg cgatctttca gagaagatcc ctgaaacggc ttcttcaaca caccgtcggc
    14341 cttgcaggac tccgcctgtt tggacacctc gtcgttcaca atgccgctga tcagtagtac
    14401 ggggagatcg gccaggttgg cttgcccgcg gatgaacgcg cacacttcgt agccactctt
    14461 gtcgggcatg atgacatcgg agacgatcag atccggacga tcttttgcca gcatcgccag
    14521 ggcttctgat ccgttggccg ccagcgtgac gcccattccg gcctcagtca aaagtcgttc
    14581 ggctaccttg cgcaccgcaa tgctgtcatc ggcaatcaag atctttggca tgtcattcct
    14641 ctacgcgatg tcggatgcat caagccggac gctgtgatgc gacccctaaa gttgccaggt
    14701 tgatgagcgg cagttgttcg tcgcctgcga cacaggatcc ggcgatgtcc ggatcgaggc
    14761 cgctttgata ctgtacccct gagcgcggca ccacatgcag cgatggcacc tgagaatcga
    14821 tgcaaatggc aagaggaccg tcgacatgtt tgacgatcag acagagcgac tcctcttcgc
    14881 gcaccgtacg gttgaatttt gctgcaagat cgaagaccgg caggcacgat tcctcatggc
    14941 ggaccagcga ggtgacaagc ggcgtatcac tgggaacagc ggtcgttcca ggccaaggga
    15001 ggacaccgcc gatctcttcg gtcctggcag ccagccgttt tcccgccacg gaaaacacca
    15061 ccatattttg cacgcgcgca tgggcagcac ctgaggccgt cgtgtgggga tgtctgcgta
    15121 attggctacg tagcatgatg accctcgacg cttaactcac agggctcgtc gacatcgaca
    15181 tcgcctcatc cacacccacc atcggcacat gcagccggga atcactctcg ccggccttgc
    15241 tctccgcaaa tcgaatcgca aacatctcca gagtttgcgc cctgagcgga agctcaagca
    15301 cccacaatgg attggcaatg agcgcgacaa aggaggcgcc gacaaaaaat cccagcaatc
    15361 gctcccgttc cttgcctcga aactgaggcg gcaagggatg aatcagcgct cgctcgacgt
    15421 ccagcaatcc cacaacttta tcaaccgcaa aggatcgcga tcgttcgtca ttgccataca
    15481 gaatcagcct ggtgtcggag gacacacctt tggagaccac cttgagtcga gcggacagat
    15541 cggttcgttc gtactccacg ccggcccacg tgaccagccc gttagggccg gccgaagctg
    15601 gcatcacgat gccgcgaacc cactgtgcag gaaaggcgac ggatgagcca ccgatcagcg
    15661 tgacaagaaa tcgaaccgct tgcccgctcg aaatggtgac tgcccgttgt cctcgaagcc
    15721 ccatatgtgt ccttcattct gccagcaacg gcacaagtcg gcaaaacctt gctatttttc
    15781 ggcccgcgcc tcaacaccgg tccacttgcg cacttcctga atcaacgccc gttcttcaac
    15841 cggtttggca atgtagcccg atgccccgac actgaccgcc atctggcgat gtttttcacc
    15901 cgcccgcgtc gtcatcacga gaatgggagt ggcatgagtt tgaggtctcg cccggagggc
    15961 ttggatgacc tcatacccgt tcaacttggg catctcgagg tcggtgataa tcagttggta
    16021 ggcctgcacc atcgccttgc ggcaaccttc ttcgccgtcc gtcgcggtct ccacggtata
    16081 ccccgcggct tcgagcatgc ggcccacaaa ctttctgatg ctgagcgaat cgtcaatcag
    16141 tagcaacggt aacgccgagg gagcactcgc ttttggctca ctatgccctg tagcatcctc
    16201 aatcgctgcg accgaagaat cctgtgcgat cgacatagtt tcctggtact cacgcgtggt
    16261 caggcggctg acgtccagca ccagcaccac ccgtccctca ggatcgatcg tcgcgccacc
    16321 gaacacggag cgttcatacg gcttcagtcc accgagagac ttaatgacga tttcctgccg
    16381 gcccagcaac tcgtcaactg cacaaccgag cgcgccggtc gaggttcgca caatcaccac
    16441 cggagacaca ccgtctgtga tccccgcctc gcgtcgaatg aggctgccca gcggatagac
    16501 ttcgatggcc tcgtccccga tttgaaccac ctgccgatcg cccatgtgtt gaagcgttga
    16561 cgccgtcgac atggtgactt cacgcacact cggcagcgga atcgcatagc ggtcttttcc
    16621 gacccgcacg agcaaggccg tggcgatcaa cagcgtgagc ggcaaatgca tggtgaactt
    16681 ggtgccctgt ccgcgcaccg actccacttc gatatggccg ttcatcgtct cgatgacgcg
    16741 tttgaccaca tccatcccga cgccacgtcc cgcttggtcg ccgacggcgt cagcggtgga
    16801 gaatcctggc aggaagatga atttgatgac ttcgctctcg ggaagggttt cagcgacatc
    16861 ctgcctgacg agtcccaact tgacggcctt cgccttgatc ttggcgatgt cgagacccgc
    16921 gccgtcatct tcgacctcga tcagaaccga gttgccgcga tgcgcggcgt gcaggtaaat
    16981 cgtgccggtc tccggcttgc cttggacacg gcnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17101 nnnnnnnnnn nncgatgcgc ggcgtgcagg taaatcgtgc cggtctccgg cttgccttgg
    17161 acacggcgga cggcggccgg ttcaatgccg tggtacacgg catttctgac taaatgcacc
    17221 agcgggtcca ccaaccgctc cacgacgccc gtgtcgattt cggtatgttc accggaagtg
    17281 accagattca cgtcttttcc cgtagccctg gccatttcgc gcgccgcacg ccggaaacgg
    17341 gtaaacggag tgccgatggg caccatacgg gcacgggcga tttcatcgcg catcccgagc
    17401 gtcaattgct gcagcgatcc catgtcgtcc tgggcgcgat ggattgatcc tgacaactgc
    17461 gacatcgatt cgctgatgtc tgccgtcacc tcgctgatgc gacgagccag aatattgaag
    17521 tcatcgtact tatcgaattc cagactgccg aaatcgctga caccgggaaa gccttgaggc
    17581 atcgcttctc cctgggtggt gggagatggc tgaaacgaga aggtgtgttt gtcttcgaac
    17641 gtgcgtacgg cgtcggtgag tcgattctta ttggccaaca cttgcgtagc caattgatcc
    17701 agggtgcgca agcgctgttc gagacgaccg cgatcaatca ccaattcgcc gaccagattg
    17761 aggagccgtt ccaagcgatc acggctgacc cggatcacct cacgctcttc tccggccttc
    17821 ccctcagcgg cattcaccgg ctcagcttgt tcagcctcct gcacatcaag cgcaatcacc
    17881 gcttcggtct gcgatgacat gacaggctca tggactcctg ccggtgcagc ttcacctagc
    17941 cccttcagtt cttgtagcga ggcggcaaac cgctgccgcg tccgagtgac caacgacggg
    18001 tcgcgccgca tcagggctcg aatgacgtcg atggctcgca ggaggacatc cgtatggccg
    18061 ggaagaaact tcaggcggcc ctcgcgaacc gcacccatga aatcttcgat gtggtgtgtg
    18121 aggtcgccga ttgattggaa ccccacggta taggctgatc cctttaacgt atgggccgtg
    18181 cgaaacagtt gatggatgat gtcagggttt gccgcatcct tgtccactcg caacaagtcg
    18241 gtctcgagac tttccagata ttcctgcgcc tcgggagcga aataggagat gacttcggca
    18301 tccagcatcg gaatgagata cgcctccgac aattcggccg ggtgattcgg ctctgagagc
    18361 tgggctgcgg gatttagagg cttcgcggca ggagggagtg cttcctcggc agcaacactg
    18421 ctgctcgatg ccgcgggcgc atcaacctgt ggagcttggg tcatgccttg ctcgagctcg
    18481 cgaagcatcg tcgtcataca aggcacgtcc tgccgcaacc gtggtagctg ctgcgcgtct
    18541 cgcgccatca acgagcgcat cacgtcgacc gcatgccgaa tcgtcgcaat ccactgtggt
    18601 ccaatgaccg ccgctccctc acgaaccgcg atcatgcagg tttcgatcgg gaatgccaca
    18661 tcacccacca cctggaatcc gaccgtgtag gcggagcctt tgagtgtatg ggcgacacga
    18721 tacagctggt ggatcgtctc cgcgtcagac aggtcgagct ctaaccgctg gagaagcgtc
    18781 tgaatcgtat tgagatactc ttccgcttca ggggcgaagt acga
//
LOCUS       DAOQPD010000080        18139 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1548_length_18139_cov_22.067076, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000080 DAOQPD010000000
VERSION     DAOQPD010000080.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 18139)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 18139)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18139
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1548_length_18139_cov_22.067076"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(103..3204)
                     /locus_tag="PK063_15275"
     CDS             complement(103..3204)
                     /locus_tag="PK063_15275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="HMZ98460.1"
                     /translation="MNISAPFVRRPVATTLLTIGATFIGIVAFQFLPVAALPQVEFPT
                     INVSASLPGASPEIMASSVAAPLERQFTRIAGVTEMTSSSTMGGTNVTLQFELDRDID
                     GAARDVQAAINASRVDLPPNLPSAPRYSIVNPADGPILILAITSELVTRGQMYDAASS
                     ILQQKLSQVEGVGQVAVGGGSLPAVRVDLNPTALNKYGIGLGDVREVLTSTNVNRPKG
                     QLTSDDRTWQIRTNDQLHKADEYLPLIVAYRNGRAVHLSDVASVESSVEDLRTMGVAN
                     GTPAVLVIVYRQPDANIIETVDRLRARLPQLEASLPGSMSLSIVMDRTPVIRASLHDV
                     ERTLAISVALVILVVFVFLRNLRATLIPAVAVPVSLISTFGVMYLLDYSLDNLSLMAL
                     TIATGFVVDDAIVVLENITRYREQGVPAMEAALRGAKDIAFTVVSMTVSLVAVFIPVF
                     LMGGMLGRLFREFAVTLSVAIGVSLLVSLTTIPMLCARVLKSETNVAHGWWYRISERG
                     FNVMLRGYATSLGWVLRHPRTMLIVTLATMALTIYLYVLVPKGFFPQQDTGRLFGNIR
                     AAQDISFQAMRDKLTEVVGIIKSDPAVASITGFTGGGSHSGTTNTGRMFIALKPLEER
                     GMSSEEVIARLRPKLAKVPGAPTYLQAIQDLRIGGRASSAQYQYTLQSVDLEELNTWA
                     PKVENKLRTLPEIVDVNSDQQDRGQQSLVIFDRSTASRLGLTPQLIDDTLYDAFGQRQ
                     VSIMYTPLNQYHVVMEVAPQYWQNPDALHEIYVRSPNGAQVPLSAVTRYEPANAILSV
                     NHQGQFPAVTVSFNMAVGVSLGEAVAAIDQAMHEIGLPASVRGTFQGTAKAFQSSVEN
                     QPWLILAALVTVYIVLGILYESYIHPLTILSTLPSAGVGALLALLLFKSELSMIALIG
                     IMLLIGIVKKNAIMMIDFALQSERLGEGKTPQAAIYEACLLRFRPIMMTTAAALLGAL
                     PLAVGMGVGSELRRPLGIAIVGGLLVSQVLTLYTTPVVYLLLDRLRLRWVRARESAPH
                     PAA"
     gene            complement(3201..6314)
                     /locus_tag="PK063_15280"
     CDS             complement(3201..6314)
                     /locus_tag="PK063_15280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="HMZ98461.1"
                     /translation="MNPSRLFIVRPVATVLTMIAILLAGALAYRHLPVSALPQVDYPT
                     IQVLTFYPGAGPDVMTSSITAPLERQFGQMPGLNQMTSTSSGGSSVVTLQFSLDIDLD
                     IAEQEVQAAMNSAATFLPRDLPAPPVYNKVNPADAPILTLALTSATLPLSQVRDFAET
                     RFAQKISQLSGVGLVSISGGQRPAVRIQANPRALAAYGLTLEDLRVVVAAANVNQAKG
                     GFDGPRRASIINATDQLFAGKDYKALIVAYRNGAPVRLSEVAEVIDDVENTKQAAWMN
                     ETPAVIVNIQRQPGTNVIEVVDRVKQLLPQLQGTLPSSVQVSVLTDRTTSIRATVRDV
                     QFELVLAVALVILVIFLFLRTLPATVIPAVAVPLSLIGTFGLMYLMGFSLNNLTLMAL
                     TISTGFVVDDAIVMIENIARYIEQGESPFQAALKGSKQIAFTILSLTVSLIAVLIPLL
                     FMGDVVGRLFREFAVTLSITILISAIVSLTLTPMMCARLLRERREEHPGPLARASQQM
                     LDRIIAGYGRSLQWVLRRQQATLLVTGATLVVTVALFVLIPKGFFPLQDTGVILGITE
                     GPQAVSFGTMAERQQALARVILEEPAVESLTSFIGVDGTNTTLNSGRVYINLKPLGER
                     VGGAGDIIRRLESRVADVEGITLHMQPVQDLTVEDRVSRTQFQYTLEDADPEELNRWA
                     PKLLEHLQLRPELRDVSSDQLNQGLASLVEIDRNTASRMGITPQLITDTLYDAFGQRQ
                     VSTMFTQLNQYRVILEVMPEFQKGPEALQALEVRGSGGSVPLNVFTRVTETTVPLVIS
                     RQGQFPAVTISFNLAPNGSLGAAVEAIRHVTQELGLPASIRGSFQGAAQAFQNSLEHE
                     PLLILAALITVYIVLGILYESYIHPLTILSTLPSAGVGALLALMLFRMEFSIIALIGI
                     VLLIGIVKKNAIMMIDFALEAERNEGKPPEQAIYEAGLLRFRPIMMTTMAALFGALPL
                     AMGAGVGSELRRPLGIAIVGGLVLSQLLTLYTTPVVYLALDRVATRFRRSREPVSVAG
                     ALPIGPP"
     gene            complement(6311..7549)
                     /locus_tag="PK063_15285"
     CDS             complement(6311..7549)
                     /locus_tag="PK063_15285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MdtA/MuxA family multidrug efflux RND
                     transporter periplasmic adaptor subunit"
                     /protein_id="HMZ98462.1"
                     /translation="MAESVRFSTLLKRWMIGLSAACLLAVGTYVTMTRSGEAQPSRSE
                     KRPPTAARNTPVVAAVAKTGEINIYLNGLGSVIPMNTVTVKSRVDGQLMRVLFKEGQL
                     VRNGELLAQIDPRPFEVQLIQAQGQMARDQAQMKNAQLDFERYRDLYKQNFIPKQQLD
                     TQEALVRQYEGIVKADQGQIDNAKLQLTYSSITAPIDGRVGLRLVDAGNIVHANDPNG
                     LLVITQLQPITVVFALAEDHLPAVFERLKSGKQLVVEAFDREQKRKLATGTLLTVDNQ
                     IDPTTGTVRLKAVFPNDDSALFPNQFVNARLLLDIKQGATIVPSAAIQRGPKGTFVYV
                     VNEAEQTVSVRAVTVGVSQGEDTSIDTGLASGETVVVDGTEKLREGSKVEMRPSGGAV
                     PTSQESPPAGGERKKQGKRT"
     gene            complement(7549..7977)
                     /locus_tag="PK063_15290"
     CDS             complement(7549..7977)
                     /locus_tag="PK063_15290"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98463.1"
                     /translation="MSRTGLWIGLSVLFCAGALMGAVGTSLYYQYEDQHRWERGPGAR
                     QERIMKRLTQELVLSTTQQAAVEPIVARAHVELLRLRVQHQPDVDRVLDQGMQELKAT
                     LSPEQQAKLDGLHAQLQQRWRMTREYVRQAQGAGGRKEER"
     gene            complement(8004..8324)
                     /locus_tag="PK063_15295"
     CDS             complement(8004..8324)
                     /locus_tag="PK063_15295"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98464.1"
                     /translation="MTVHRKPTLEQIEPLLVQAHRSRGEVPVGEDWAQEVMRAIRREA
                     AEHPAPSLLAWAEPVVWRVAAGAALVAVCFAGSVAIYTKQHAVPVAAVWLEEFDAGSA
                     FPDK"
     gene            complement(8308..>8925)
                     /locus_tag="PK063_15300"
     CDS             complement(8308..>8925)
                     /locus_tag="PK063_15300"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HMZ98465.1"
                     /translation="VSFTGAQALLSDDAECIDQVLGGDIDRFGELIARHQHHVRKIVQ
                     GHVPADHVGEVAQDVFVRAYTGLAQYGGTVPFDHWLSRLSVRACYDFWRARRRTEIPV
                     SGLSEDQVGWLDRALAEDSTHQFRDQADQRDLLEVLEWALAQLSPEHRLVLTLVSLEG
                     RSVRDAAELLGWSVVNVKVRCYRARQALRTIFLREWERHRHDRPS"
     assembly_gap    8926..9025
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(9260..10168)
                     /gene="cynR"
                     /locus_tag="PK063_15305"
     CDS             complement(9260..10168)
                     /gene="cynR"
                     /locus_tag="PK063_15305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator CynR"
                     /protein_id="HMZ98466.1"
                     /translation="MEFRHLRYFLAVADALHFTKAAEGLPVSQPALSAQIKQLEQEVG
                     VPLFDRVGRSVQLTRAGSIFREHARRALREMELAQVAIAEEEGLQRGTLTVGVVQTVN
                     AYLVPEIVGRFSTLHPHVSLKFDELSGPDIEAGVKNGVLELGIGFVPPGSDRIATQPL
                     FEEDFVLIASSRHRFATRRHLPLASLADEPLVLLPGIFCTRRLLNASFEQAGIVPRVT
                     VEMNSIEGILATVKTSKLATVLPRLSLGLERHDGLRGIPLNNPTPRRALGLLWKKGGY
                     RSGAARALADQVRLVVNKRWKQKPGK"
     gene            10295..11014
                     /locus_tag="PK063_15310"
     CDS             10295..11014
                     /locus_tag="PK063_15310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HMZ98467.1"
                     /translation="MQQVSGFIRSIQVGLPEQGHPHCHEDRPPQSWSTGIFKRPVRGP
                     IRLQQKNLEGDGQADLIHHGGVDKAVCVYPSEHWFHWSSVLPQQQLIGGEFGENFTLE
                     GLTEADVCIGDIFSVGSAVVQVSQPRQPCWKLARRWQIKDLAVQVEQTGFTGWYFRVL
                     QEGVVEPSIPLRLTDRPYPEWTVTTANRIMHQEHSNLKAAEHLSLCPLLSASWRHALH
                     QRSQQQNSPDPQPRQFGNSQS"
     gene            11038..11376
                     /locus_tag="PK063_15315"
     CDS             11038..11376
                     /locus_tag="PK063_15315"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98468.1"
                     /translation="MTRLTLSVCSLALGAILAMSSWCAAENVTTINILSPRNGDSVPE
                     TFEIKYEILNAPEGNHAHVYLDGAYQKGFKGTFTHVPKGEHTITVKIADHDHKDAGTA
                     TDSVTVKVGE"
     gene            complement(11484..12167)
                     /locus_tag="PK063_15320"
     CDS             complement(11484..12167)
                     /locus_tag="PK063_15320"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98469.1"
                     /translation="MCECINRKMFQAPLRHLAAAGLVGVLFTTLLPAPLNAARGGTSP
                     GGGKTEILPVQKAAPSVVIIDTPGSEADLRRQLRSKNGVAELGASTSKTMFSQAPTGT
                     FGFILPKFLGLALVTQSPDLVLERVSPATSAYEVHKLADGSGLLIGFMGKDVLMQVAP
                     SQRPKSVRIALHSNPSEKAPHIVAVPLVKLAADMMPLRIDPKNPDSPVVFEMDLQSSS
                     TRASTQGGQ"
     gene            complement(12262..12702)
                     /locus_tag="PK063_15325"
     CDS             complement(12262..12702)
                     /locus_tag="PK063_15325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ98470.1"
                     /translation="MGMAWPFGLSTGDKVSLGRVLVVDDEDSIRSVLRMMLTQAGYDV
                     EEADDGGKAVEVLNSGDNPLMLDAIICDIRMPRINGVEAIAYFRAQYPSLPVIVLTGY
                     HDEPLASSLRRQGIVEFLEKPAEREQILASVAQAIAGRRISFYP"
     gene            complement(13032..13211)
                     /locus_tag="PK063_15330"
     CDS             complement(13032..13211)
                     /locus_tag="PK063_15330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004153593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1328 domain-containing protein"
                     /protein_id="HMZ98471.1"
                     /translation="MFLKWAAVFFVLAMVAAAFGFTGIADKASDVAEILFYIFLAIVL
                     TFVVSGVVVARKLTA"
     gene            complement(13254..>14444)
                     /locus_tag="PK063_15335"
     CDS             complement(13254..>14444)
                     /locus_tag="PK063_15335"
                     /inference="COORDINATES: protein motif:HMM:NF012744.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HMZ98472.1"
                     /translation="GVDSSMFVREARTSDGSVIRFEPTTTFCKRAERRIRREQIERKL
                     RPAISPENDKIEPFRTDRSEYGTDILSKLPPYDILNLHWIAEFVDYPSFFGAFSKNTR
                     VVWTLHDMNAFTGGCHYDLGCGRYLGECGDCPQLAAAGPNDLSHEIWARKKSLFDQLS
                     DGQIHFATPSTWLAEEVQRSPILGRFPVSVIPYGLDLTEFSPRDVGSAREVFGIPPKA
                     KVILFVADGLPLFRKGFEVLVRALEHIRSWIPDLHLVTVGHNSPDLGHHIPHSYLGHI
                     NSDRLLSNIYSAADLLVIPSLQDNLPNTVLESMACGTPAVGFEVGGIPDMIQHCETGL
                     LVPPGEAGALGAAMLELLQNPERRMALGANCRQYALNHFSLEEQADRYCQLYTEILSE
                     RAIR"
     assembly_gap    14445..14544
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(14610..15902)
                     /locus_tag="PK063_15340"
     CDS             complement(14610..15902)
                     /locus_tag="PK063_15340"
                     /inference="COORDINATES: protein motif:HMM:NF012235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ98473.1"
                     /translation="MGNVAISVDRLTKRYSLGLQARHDTLRDRLAAALSWWKQCRSDD
                     TGKGREFCALTDVSFDVKPGEVFGIIGHNGAGKSTLLKILSRITAPTSGTADIYGRVG
                     SLLEVGTGFHPELTGRENIYLNGSILGMRRAEITAKLDEIIDFAGVEEFIDTPVKRYS
                     SGMYVRLAFSVAAHFEPDILIVDEVLAVGDAGFQQKCLGKMRQASRGGRTVLVVSHNL
                     PIIENLCQRALFLAQGRVALTGTARDVVQAYAGMTADLARSALDTRTDRQGKGHVIAT
                     AIEVLDQYRNVSSSAICGRETIVRWHYRCVPDKIIRRCRVELSLHARIGDPYETAYFL
                     MSTDLVSPLPLDLSGDGYIDFRVPEWPLSGGQYYVMSYVESDKEVQDWVHNASLLSVV
                     DGDFYGIGKSYPPNWRGKSVLVKYDWTQTAREAVHSFL"
     gene            complement(16031..16396)
                     /locus_tag="PK063_15345"
     CDS             complement(16031..16396)
                     /locus_tag="PK063_15345"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98474.1"
                     /translation="MMSQRLSNWSRRGWMVVMLAVGALTAGCMHHPGGIAPSTKPLAP
                     GGYTELGKVRGQDCVYHLLGLIPVTGGNEMRNAVEDALRTKPLADAMVEVTVDGYFQY
                     FILFSRACTQVYGTAVETK"
     gene            16875..17939
                     /locus_tag="PK063_15350"
     CDS             16875..17939
                     /locus_tag="PK063_15350"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HMZ98475.1"
                     /translation="MITASGAVILILIGLLLGLGEVIIRSVHLIRDGIPFFESNAGGR
                     IGPITLDQDLGWKATEHYQEALVEKTKNGTLYPVRRSQTQYGFRSFGDVSSRRPKMLV
                     MGDSFTHATAVSDDRTYHALLSKLLDVEVFAYGAGGYGTLQEYLVFDRYLDIVRPDVI
                     LWQYCINDFINNDNELERLSRVNNNGWVRPYWRNGTIQLLSPKESSLQIRDWINRHSR
                     FLYFVVTRLDRLRAANTRDTVEVDIEAEGMRHAGFARSVAVTDDLMGRVRARAGTRPI
                     MAFNCTEAEPYSQAFRDISGHHAIAYWGDVAQVVQDADTRGEDVFAADGSHWNERGHE
                     LAAQALAKHFKTALPPVPRP"
BASE COUNT         3950 a         5522 c         4932 g         3535 t
ORIGIN      
        1 tcttgatagc aattctcaat atcatgaccg cgaaacagtt gtcaatgcgc atatcgccct
       61 actcacggcg gcgaagcact tccatgtata tcgtgcgagt ccctatgcgg cgggatgagg
      121 agcgctctct cgggcgcgga cccatcgcag tcgcagacgg tcgaggagca ggtagacaac
      181 aggagtggtg tagagggtga gaacctgact caccagcaac ccgcctacga tggcaatacc
      241 gagcgggcga cgcagttccg atcccacccc catgccaaca gccagaggca acgcacccaa
      301 gagggcggcc gcggtggtca tcatgatcgg tcggaaccgt aacaggcagg cttcataaat
      361 cgccgcctgg ggagtttttc cttctcccag gcgttcactc tgcaaggcga aatcgatcat
      421 catgatggca tttttcttca caatgccgat caagagcata attccaatca aggcaatcat
      481 gctcaactca gacttgaaca gcagcaatgc caacagggcc ccgaccccgg cggacggcag
      541 cgtggaaaga atggtgaggg gatgaatata actctcatac agaatcccca gcacgatata
      601 caccgtgact aacgccgcca ggatcaacca gggttggttc tctacagacg actgaaacgc
      661 tttggccgtt ccttggaacg tccctcgcac actcgccggc aatccgatct catgcatcgc
      721 ctggtcgatc gccgccaccg cctcaccgag cgacacgccg accgccatgt tgaaggacac
      781 ggtcaccgca ggaaactgcc cctggtgatt gacggacaag atggcattgg ccggttcgta
      841 ccgtgtcacc gcactcaatg gcacttgagc accattcggc gaacggacgt aaatttcgtg
      901 gagtgcgtcg ggattctgcc aatactgcgg cgcgacctcc atcacgacat ggtattgatt
      961 gagcggcgta tacataatcg aaacctgccg ctgaccgaac gcatcgtaga gggtgtcatc
     1021 gatcaattga ggcgtcaaac cgagtcgtga cgcggtactc cggtcgaaga tcaccagcga
     1081 ttgttgaccg cgatcctgct gatcgctatt cacgtccaca atctccggca aagtgcgtaa
     1141 cttgttctcg actttaggcg cccaggtgtt gagttcctcc agatccacgc tctggagagt
     1201 atattgatac tgcgcactgc tggcccgccc gccgattcgc agatcctgga tagcttgcag
     1261 ataggtcggg gcacccggca cttttgccag cttcgggcgt aaccgggcaa tgacttcctc
     1321 ggaactcatg ccgcgctctt ccagcggttt caatgcgatg aacatacggc ccgtattggt
     1381 ggtgccggaa tggctccctc cgccggtgaa cccggtgatg ctcgccaccg ccgggtcgct
     1441 cttgatgatc cccaccacct cggtcaactt gtctcgcatg gcctggaacg aaatatcctg
     1501 cgcggcacgg atgtttccga agaggcgccc cgtgtcctgc tgcgggaaaa accccttcgg
     1561 caccaataca tacagataga tcgtaagggc catggtcgcc agggtcacga tcaacatggt
     1621 gcggggatgc cggagaaccc agcccagact cgtggcatat cctcgcagca tcacattgaa
     1681 tccccgctcg ctgatgcgat accaccatcc atgggcgaca ttggtctccg acttcaatac
     1741 tcgcgcacac agcatgggaa tcgtcgtcaa cgacaccagc aatgacactc cgatcgccac
     1801 cgaaagcgtc acggcaaatt cgcgaaacaa ccgccccagc atcccgccca tgagaaacac
     1861 cggaatgaac accgccacca aggatacggt catcgacacc accgtaaacg cgatgtcttt
     1921 cgctcctcgc aacgccgctt ccatggccgg cacgccctgc tcacgatagc gtgtgatgtt
     1981 ttccagcacc acgatggcat cgtccaccac aaaaccggtc gcgatcgtca aggccatgag
     2041 cgacaggttg tctaagctgt aatcgaggag atacatcacg ccgaacgtgg aaatcagcga
     2101 cacgggcaca gccaccgcgg ggatgagtgt ggcgcgaagg ttccggagaa acacgaacac
     2161 gacgagaatg accagggcga ccgagatcgc gagggtccgc tccacgtcgt gcaaggaggc
     2221 acggatgacg ggagttcgat ccatgacgat cgacagcgac atgctccccg gcagcgacgc
     2281 ttccagctgc ggcaaccgcg cgcgaagccg atccaccgtc tcgatgatgt tggcatcagg
     2341 ctgccggtag acgatcacca agaccgccgg tgtaccattc gcgacaccca tagtccgcag
     2401 gtcttccacc gatgattcca cggaggccac atccgacaga tgcaccgccc gtccgtttcg
     2461 ataggctacg atcaacggca gatattcatc cgctttatgc aactgatcat tcgtccggat
     2521 ctgccaggtg cgatcatccg aggtgagctg tcccttcgga cgattgacgt tcgtactggt
     2581 cagcacctcc cggacgtcgc ccagtccgat gccatactta ttcagggcgg taggattcaa
     2641 atcgacacgg actgccggca aggagcctcc gcccaccgcc acctgcccga cgccttccac
     2701 ctgcgagagt ttctgctgca agatgctcga cgccgcgtcg tacatttgtc cgcgcgtgac
     2761 gagttccgag gtaatggcca gaatgagaat gggcccgtcg gccggattca caatgctgta
     2821 gcgaggtgca ctcggcaggt ttggcgggag atcgacacgg gaggcattga tcgccgcttg
     2881 cacgtcgcgc gcagcgccat cgatgtcacg gtcgagctca aactgcagtg tgacgttggt
     2941 gcctcccatc gtgctggagg atgtcatttc tgtcactccg gcaatccggg tgaactgccg
     3001 ctccagcgga gccgccacgg acgaggccat gatctcaggg ctggctcccg gcaacgaggc
     3061 tgatacattg atcgtcggaa actcgacttg cggtagtgcg gcaaccggaa ggaattgaaa
     3121 cgccacgatc ccgatgaacg tcgcaccaat ggtcaataac gtggtggcaa ccgggcgccg
     3181 gacaaagggg gcggagatgt tcatggtgga cctatcggca gcgcaccggc cacggacacc
     3241 ggttcgcgac tgcggcggaa acgcgtcgca acccgatcca aagccagata caccacaggc
     3301 gtggtgtaga gcgtgaggag ctggctcaag accaatcctc ccacgatcgc gatcccgagc
     3361 gggcgtcgta attccgagcc cacccctgcc cccatcgcca gaggcaaggc gccgaagagc
     3421 gcagccatgg tggtcatcat gatcgggcga aaccgcaaca gtccggcttc gtagatggcc
     3481 tgctctggtg gtttaccttc gttgcgctca gcctccaagg caaagtctat catcatgatg
     3541 gcgttcttct tcacgatgcc gatgagcaac acaatcccga tcagcgcgat gatgctgaat
     3601 tccatacgga acaacatgag ggccagcagc gcgccgacac ccgccgaggg aagggtggag
     3661 agaatcgtca gcggatggat gtagctctca tacaaaatac caaggacgat gtagaccgtg
     3721 atcaaggcgg ccagaatcaa cagcggttca tgttccagag agttttgaaa ggcctgcgcc
     3781 gcgccctgaa aacttccgcg gatactggcg ggaagcccca attcctgcgt gacatgccga
     3841 atcgcttcca ccgccgcgcc aagcgaacca ttcggcgcaa gattgaacga gatcgtcacg
     3901 gcgggaaact gcccctgccg gctgatgacc agcggcacgg tggtctcggt caccctggtg
     3961 aagacattca acggcaccga tccgccgctg cctctcacct ccagagcttg cagggcttcc
     4021 ggtcctttct gaaattccgg catcacctcc agaatgacgc gatactgatt caactgcgta
     4081 aacatcgtcg aaacctgccg ctggccgaac gcatcgtaca aggtatccgt gatgagttgc
     4141 ggcgtgatgc ccatgcgtga cgcggtattg cggtcgatct ccacgagcga ggccaatccc
     4201 tgattcagtt gatcgctgct gacatcgcgc agttcagggc gcagctgcaa atgttccagc
     4261 agtttcgggg cccaccggtt caactcctcc ggatcggcat cttccaacgt gtattgaaac
     4321 tgcgtccgac tcacccgatc ttccaccgtg aggtcttgca ccggctgcat gtgcaaggtg
     4381 atcccttcca cgtcggccac acgtgattcc agccgtctga tgatgtcacc ggcgcccccc
     4441 acccgctcgc ccaaaggttt cagattaatg tacacgcgcc cgctgttgag cgtcgtattc
     4501 gtgccgtcca caccgataaa tgacgtgagg ctttccacag ccggttcctc aagaatgacg
     4561 cgagccagag cttgctggcg ttccgccatc gtgccgaacg agaccgcttg cgggccttcc
     4621 gtgatgccga ggatgacgcc tgtatcctgg agcggaaaaa atcctttggg aatcagaaca
     4681 aacagcgcga ccgtgaccac cagcgtggcg cccgtcacaa gcagcgtcgc ctgttggcgc
     4741 cgaagtaccc actgcagact tctcccatag cccgcgatga tgcgatccag catttgctgc
     4801 gaggctcgcg ccaacggccc cggatgctcc tcccgccgtt cgcgcaaaag cctggcgcac
     4861 atcatcggag tcaacgtgag cgacacgatt gccgaaatga ggatcgtaat gctcagcgtc
     4921 acggcaaact cccggaataa ccgtcccacc acatcgccca tgaacaacaa cgggatcaat
     4981 actgcgatca gggacacggt caacgacagg atcgtgaagg cgatttgctt ggaccccttg
     5041 agagcagcct ggaaaggcga ttccccctgt tcgatgtatc gcgcgatgtt ctcgatcatc
     5101 acgatggcat cgtcgaccac gaagcccgtg gagatcgtca gcgccatcaa ggtcagatta
     5161 ttcaggctga accccatgag gtacatgagg ccgaaggtgc cgataagaga gaggggtacg
     5221 gccaccgccg gaatcaccgt ggccggcaat gtgcggagaa acaaaaaaat caccagaatc
     5281 acaagggcca ccgctagcac caattcgaac tgtacatcgc gaacggtcgc gcgaatcgaa
     5341 gtcgtgcgat cggtcagcac ggagacctgc acggatgacg ggagggttcc ctgtagctgc
     5401 ggcagcaact gcttgacgcg gtcgaccact tcgatgacat tcgtccccgg ctggcgctga
     5461 atgttgacga tcaccgccgg cgtctcgttc atccaggccg cctgcttggt attttcgaca
     5521 tcgtcgatga cctcggcgac ttccgacagc cgaaccggcg cgccgttgcg ataggccacg
     5581 atcagcgcct tatagtcttt gccggcaaac aattggtccg tggcgttgat gatggaggcg
     5641 cgacgcggcc cgtcgaaacc gcccttggcc tggttcacat tggcggcagc caccaccacg
     5701 cggagatctt ccaacgtcaa cccgtaggcg gccaacgcgc gcggattcgc ctgtatccgc
     5761 accgccggac gctggccccc gctgatgctt acgagaccga caccggacaa ttgcgaaatc
     5821 ttttgcgcaa accgggtttc ggcaaagtca cgcacttgcg acagaggcaa ggtagcggag
     5881 gtcaacgcca gcgtgaggat cggcgcatct gcggggttaa ctttgttgta gaccggcggc
     5941 gcaggaagat cgcgaggcag gaaggtggcc gcggaattca tggccgcctg cacttcctgc
     6001 tcagcgatat ctagatcgat gtcgagactg aattgaaggg taacgaccga actgcccccg
     6061 gaactcgtgg aggtcatctg attgagcccg ggcatttgcc cgaactgccg ttccagtgga
     6121 gccgtaatgg aagacgtcat cacgtccggc ccggcgccgg gataaaacgt caacacttga
     6181 atggtgggat aatcgacctg cggaagcgcg gaaacgggca gatggcgata tgccagcgcg
     6241 ccggccagca gaatcgcgat catcgtcaag accgtcgcca ccggccgcac gatgaacagc
     6301 cgcgaagggt tcacgtgcgt ttcccctgtt ttttccgttc tcctcccgcg ggcggactct
     6361 cctggctggt cggcactgct ccgcccgatg gacgcatctc gaccttgctg ccttcacgca
     6421 acttttccgt tccatccacc acaacggttt cacctgatgc caggccggta tcgatcgagg
     6481 tgtcttcgcc ctgtgacaca cccacggtca ctgcgcgcac gctgaccgtc tgttccgcct
     6541 cattcaccac gtagacaaat gttcccttgg gaccgcgttg aatcgcggcc gacggcacga
     6601 tggtcgcacc ttgcttgata tcaaggagca ggcgggcgtt cacgaactga ttggggaaga
     6661 gcgcgctgtc gtcgttggga aacaccgcct tcagacggac ggtcccggtg gtcgggtcga
     6721 tttgattgtc gacggtgagc aacgtccccg ttgccaattt gcgcttctgc tcccgatcga
     6781 aggcctccac caccagctgc tttcccgact tgagccgttc gaacaccgcc ggcagatgat
     6841 cttccgccaa cgcaaagacg acggtgatcg gctgcaattg cgtgatcaca agcaatccgt
     6901 tgggatcgtt ggcatgcacg atattgcccg catctacgag gcgcagcccg acccgcccgt
     6961 cgatcggcgc ggtaatgctc gaataggtca gttgcaactt ggcattgtcg atctgtcctt
     7021 ggtccgcctt gacgatacct tcatactgac gcacaagggc ttcctgggta tcgagctgct
     7081 gtttgggaat gaagttctgt ttgtacaggt cccggtagcg ttcaaagtcg agctgtgcat
     7141 tcttcatctg cgcctggtcg cgcgccattt gtccctgcgc ctggatcaac tgcacttcaa
     7201 aggggcgggg gtcgatctgc gccaataact ctccgttccg cacgagttgg ccttccttga
     7261 agagcacgcg catcaactgg ccatccaccc ggcttttcac cgtgacggta ttcatcggga
     7321 tgacggaccc caggccgttc aaataaatgt tgatctcacc ggtttttgcc acggccgcca
     7381 cgaccggggt attgcgcgca gccgtcggtg gacgcttttc cgaccgactg ggttgcgcct
     7441 caccggagcg ggtcatcgtg acataggttc ccacggccaa taggcaggct gcggagagcc
     7501 cgatcatcca tcgtttcaag agagtggaaa atctcaccga ctcagccatc accgctcttc
     7561 cttccgtccc ccggcaccct gcgcctgccg gacatactcg cgggtcatgc gccagcgctg
     7621 ctgcaactgg gcatggagtc cgtctaactt ggcctgctgc tcaggcgata atgtcgcctt
     7681 caattcctgc atcccctgat caagcactcg atcgacgtcc ggttgatgct gcacgcgcaa
     7741 ccgtaacaat tccacatggg ctcgcgccac gattggctca accgcggctt gctgagtcgt
     7801 cgacaatacc agttcctggg tcagccgttt cataatccgt tcctgccggg ctcccggccc
     7861 ccgctcccat cgatgctgat cttcgtactg ataatacagt gacgtcccca cggcgcccat
     7921 caaggctccg gcgcaaaaga ggacactcag tccgatccac aatccggtgc gtgacatacc
     7981 tcgcgctcga gcctccgaac gagttattta tcaggaaacg ctgatcccgc atcaaactct
     8041 tcaagccaga cggcggcgac cggaacggca tgctgcttgg tatagatggc cacagagccg
     8101 gcaaagcaga cggccacgag cgcggcaccg gcagccacgc gccagactac cggttccgcc
     8161 caggcgagga gcgacggcgc aggatgttcc gcggcctccc gccgaatcgc tcgcatgacc
     8221 tcctgcgccc aatcctctcc aacaggcact tcgccgcgac tgcgatgcgc ctgtaccaga
     8281 agcggctcaa tctgctcaag tgtaggctta cgatggacgg tcatgccggt gacgctccca
     8341 ttctcgaaga aatatcgtcc gtaaggcttg cctggctcga taacaccgca ccttcacgtt
     8401 caccaccgac catcccaaca gctcggccgc gtcgcgcacg cttcggccct ccagcgaaac
     8461 caaggtcaac accaggcggt gctcgggtga cagctgcgcc aacgcccatt ccaacacttc
     8521 gagcagatca cgctgatcgg cctggtcacg gaactggtga gtcgagtctt ccgccagcgc
     8581 gcgatccagc catccgactt ggtcttcact cagcccgctg acaggtatct ccgttcgccg
     8641 acgggcacgc caaaaatcat aacaggcccg aacgctcagg cgagacaacc aatggtcgaa
     8701 tggaacggtg cctccgtatt gcgcaagccc tgtataagcc cggacgaaca cgtcttgcgc
     8761 aacctccccc acatgatccg ccggcacatg tccttgcaca atcttgcgca catggtgttg
     8821 atgccgggcg atcaattcgc cgaaccgatc gatatcaccg cccaaaactt gatcgataca
     8881 ttcggcatca tcggacaaga gtgcctgcgc tcctgtaaag ctgacnnnnn nnnnnnnnnn
     8941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9001 nnnnnnnnnn nnnnnnnnnn nnnnngatcg atacattcgg catcatcgga caagagtgcc
     9061 tgcgctcctg taaagctgac cgtcctccct gcttacagca tggacctcag catcataccc
     9121 catccgccct caggaccgca ggcgtggccc tcttattatg ttagtcgttg atagaccggc
     9181 aaaggttaca cgtgaccaca cacaatcgct caggccggaa ggctgactgg gccgtgccct
     9241 atcaaccctg gtctacgagt cacttacccg gcttctgttt ccagcgcttg ttaacgacga
     9301 ggcgtacctg atcagccaga gcccgggccg ccccgcttcg gtacccgccc ttcttccata
     9361 acagcccgag agcgcggcga ggtgtgggat tgttgagtgg aatcccgcga agcccgtcat
     9421 gccgctctaa gcccagagac agccggggaa gcacggtcgc cagtttgctg gtcttcaccg
     9481 tcgcgagaat cccttcgatc gaattcattt ccacagtcac cctaggcacg atacccgcct
     9541 gttcaaaact tgcattcagt aaacggcgcg tacaaaaaat acccggcagg agcaccaggg
     9601 gctcatccgc gagagacgcc aatggcaggt ggcggcgtgt ggcgaagcga tgccgggatg
     9661 acgcaatcaa gacaaaatct tcctcaaaga gtggctgagt cgcgatacga tccgatccgg
     9721 gaggaacgaa cccgatgcct aattccagga ctccgttctt cacaccggct tcgatgtccg
     9781 gcccggatag ttcatcgaat ttcagcgaga cgtgcggatg cagcgtcgag aaacgtccga
     9841 cgatttcggg aaccagatag gcattgacgg tttgcaccac gccgacggtc agggtaccgc
     9901 gctgcagccc ttcctcttca gcaatggcca cttgcgccag ttccatttca cgcagggcac
     9961 gccgggcatg ttcccgaaaa atcgatccgg cccgggtcaa ttggaccgat cgcccaaccc
    10021 ggtcgaagag cggcacgccg acttcctgct ccaactgttt gatctgggcg gacaaggccg
    10081 gctgagagac cgggagccct tcggccgctt tggtaaaatg caacgcgtcg gccaccgcga
    10141 gaaagtaccg gagatgacgg aattccatac cacctcttat cataactaga agtgattgat
    10201 ctaatcagaa caaacacttt gacgcctgaa cgggcctggc actagggtga cgccggtcac
    10261 tcgcgtcgtt gtctaacgga tcgaacagca tcacatgcag caggtcagcg gtttcatacg
    10321 ttccattcag gtgggtctgc ctgagcaggg tcatccgcac tgccacgaag atcgcccccc
    10381 gcaatcctgg tccaccggca tcttcaagcg tccagtccgt ggccccattc gcctccagca
    10441 aaagaacttg gagggtgacg gccaagcaga tctcatccac cacggaggcg tcgacaaggc
    10501 ggtctgtgtg tatccgtccg agcattggtt tcactggagc agcgtcctcc cgcagcaaca
    10561 actcatcggc ggcgagttcg gcgaaaactt tactctcgaa ggactgacgg aagcagacgt
    10621 gtgcattgga gacatttttt cagtggggtc cgctgtcgtg caggtatctc aacctcggca
    10681 gccctgctgg aagctggccc ggcgctggca gatcaaggat ctggcggtgc aagtggaaca
    10741 gaccggattc acgggatggt attttcgcgt cctccaagaa ggtgtcgtcg aaccaagcat
    10801 cccgttacgc ttaacggatc gcccgtatcc cgaatggacg gtcaccaccg cgaatcggat
    10861 catgcatcag gaacacagca acctgaaagc cgctgaacac ttgagcctct gcccgttgct
    10921 ctctgcaagt tggcgacacg cattgcacca gcggagccag cagcagaaca gtccggatcc
    10981 gcagccacgt caattcggca attctcaatc ctaatcacca ttctttccgg aggtgttatg
    11041 actcgtctca ctctatccgt ctgcagtctg gcccttggcg ccattctcgc catgagttcc
    11101 tggtgcgccg ctgaaaatgt gaccaccatc aacattttgt ctccgcgcaa cggcgactcc
    11161 gtcccggaaa cgttcgaaat caagtatgag attttgaatg cgccggaggg gaatcatgct
    11221 cacgtctacc tggatggcgc ctaccagaag gggttcaagg gtaccttcac gcacgtgcct
    11281 aagggcgaac ataccattac ggtcaaaatt gccgatcatg atcacaaaga tgcaggaacg
    11341 gcgacagaca gcgtaacggt gaaggtcggg gagtaggagg aagcctcggg cgacgagagt
    11401 gcgcctgata cggtgcggct ttcaaaatcg cacggccgga aggcggccca ctgtccgccg
    11461 ccttcctcac cagtgctcag cgcctattgc ccgccctgtg tcgacgcacg ggtggacgag
    11521 ctctgcagat ccatctcaaa cacgaccgga ctgtctggat ttttcgggtc gatccggagg
    11581 ggcatcatat cggccgcgag tttcaccagc ggcaccgcca caatgtgcgg agccttttcc
    11641 gatggattcg aatggagtgc gatacgaacg ctcttcggcc gctgactagg cgccacttgc
    11701 ataagcacgt ccttacccat aaacccaatc agcaagccgc ttccatcagc cagcttatgc
    11761 acctcatacg cactcgttgc aggagacacc cgctccagaa cgagatccgg actctgcgtg
    11821 accagggcca gccccaggaa ttttggcaga ataaagccaa acgtgcccgt cggggcttgg
    11881 gaaaacatcg tcttggaggt cgacgcgccc agttccgcca ctccgttctt gctgcgtaac
    11941 tggcgacgca gatccgcttc gcttcccggc gtgtcaatga tcacaaccga aggagccgct
    12001 ttttgaaccg gcaagatctc cgtttttcct ccaccgggac tggtcccgcc gcgtgcagca
    12061 ttgagggggg ccggcagaag cgttgtgaaa agaacaccca ccaagcccgc ggccgcgaga
    12121 tgacggagcg gcgcctggaa catctttcga ttgatacatt cacacatgag tactgatcct
    12181 cctgaacaag ggagagctgt cgttccggag gattctaaga agccgactca cgaaaatcaa
    12241 acaggaagga gtgcacttgc ctcacggata gaagctgata cggcgtccgg ctatggcctg
    12301 ggcgacggat gccaggatct gctcccgctc cgccggtttt tcgagaaatt ccacaatgcc
    12361 ctgtcggcgt aacgaggagg ccaatggctc gtcatgatag ccggtcagta cgatgaccgg
    12421 cagagatgga tattgggctc gaaaataggc aatagcctcc acaccattga tgcgcggcat
    12481 ccggatatcg caaataatcg catccagcat cagcgggttg tcgccgctgt tcaacacttc
    12541 caccgctttc ccgccgtcgt ccgcctcctc cacatcgtac ccggcctgcg tcagcatcat
    12601 gcgcagcacg ctgcggatcg agtcttcgtc atccaccacc aagacccggc ccaggctgac
    12661 cttgtcgccc gtacttagtc cgaacggcca tgccattccc atggtgtccc tcccttcgcc
    12721 agacgcatgt gtttccctgg gttggcgatg caaggacaag gccttcgacc tatcggactc
    12781 gacatgaccc gattcaacaa gttagcgatc gagatcttct gtccatcgcg tggaacgcct
    12841 ctttcaagtg gtggaatcac accacctcgg tgcaaatgca ccaaagctca cagtgaagta
    12901 tggtgagggg tggaagacgt tcaggaagga cagcggccgg cacagagatg caccggccgc
    12961 gtaaacagct ggggcggcct cgacatcaac atgtcctcat agcgatacgg tccgctatag
    13021 agaggaggga ctcacgccgt cagtttgcgt gcaaccacca cacccgagac cacaaaggtg
    13081 aggacgatcg ccagaaagat gtaaaacaga atttccgcta catccgacgc cttgtccgca
    13141 attcctgtga atccaaatgc cgcagccacc atggccagaa cgaaaaatac tgctgcccat
    13201 ttgagaaaca tacccacctc ctcggctcag attcccgatc ccagcactcg actttaccga
    13261 atggcacgtt cgctcaagat ctctgtgtac aattggcagt accgatcggc ctgttcttcg
    13321 agagaaaaat ggttgagggc atattggcga cagtttgcac ccagcgccat gcggcgctca
    13381 gggttttgca gcagttccag catggcggca cccaatgctc ctgcctcacc gggcggcacc
    13441 agcaagccgg tttcacaatg ttgaatcatg tcgggaatcc ctccgacttc aaaccccacc
    13501 gccggcgttc cacaggccat cgactcgagc accgtattcg gcaagttatc ctgcaacgac
    13561 gggatcacga gcagatcggc tgcgctgtaa atgttggaga gcaatcgatc gctgttgatg
    13621 tgtcccaggt aggagtgagg aatatgatgt cctaggtcgg ggctattatg gcccaccgtg
    13681 acgagatgaa ggtccgggat ccagctgcga atatgctcca aggcccgtac cagaacctca
    13741 aatcccttcc ggaacagcgg gagcccgtcg gctacaaaca gaatgacttt cgctttagga
    13801 ggaatcccga agacctctct ggcactgccg acatcgcggg gcgagaactc cgtgaggtcg
    13861 agcccatagg gaatcaccga cacagggaac cggccgagaa tcgggctgcg ctgcacttcc
    13921 tcggcgagcc acgtgctcgg agtcgcgaag tgaatctgcc cgtcggaaag ttggtcgaag
    13981 agtgatttct tgcgggccca gatttcatgg gagagatcat tcggccctgc ggcagccagc
    14041 tgaggacagt ctccgcattc accgagatag cggccgcacc ccagatcgta atgacagccg
    14101 cccgtaaacg cattcatgtc gtgaagtgtc cacaccacgc gcgtattctt cgagaaggcc
    14161 ccaaagaagg aggggtaatc cacaaattcc gcaatccagt gcaggttcag aatgtcatag
    14221 ggcgggagtt tcgacaaaat gtcggtccca tattccgagc gatccgttcg gaatggttca
    14281 atcttgtcat tctcgggaga gatggcgggg cggagcttgc gttcgatttg ttcacgccgg
    14341 atgcggcgct cggctcgttt acagaaagtg gtggtcggct cgaaccgaat gacagatccg
    14401 tcagaggttc gggcttcgcg gacaaacatg gacgaatcga cgccnnnnnn nnnnnnnnnn
    14461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14521 nnnnnnnnnn nnnnnnnnnn nnnntctcct tgctccacta ggcatacccc gaggaatcac
    14581 tcgtcgcgag gccgctcgaa atggagtgat cacaggaagg agtgcaccgc ctcgcgggcc
    14641 gtctgcgtcc aatcatattt caccaacaca gacttgcctc tccaattggg aggataactt
    14701 tttccaatcc cgtaaaagtc tccgtcgaca acggacaata ggctggcgtt atgcacccaa
    14761 tcctgaacct ctttgtcact ttccacgtac gacatcacat agtactggcc gccggagagg
    14821 ggccattccg gaacccggaa atcaatgtag ccgtctccgg acaaatcgag tggtagcggg
    14881 ctcacgagat cggtggacat gagaaaatac gccgtctcat aggggtcgcc gattcgagca
    14941 tgtaacgaaa gttccacgcg gcatcgccga atgattttgt caggcacgca ccggtaatgc
    15001 catcgcacga tggtctctcg cccgcagatg gccgacgacg agacgttccg atactggtcg
    15061 agcacctcga tggcggtcgc aatgacgtgg cctttccctt gtctgtccgt gcgtgtgtcc
    15121 aacgcacttc tggctaaatc ggccgtcatg cctgcatagg cctgcaccac atccctggct
    15181 gtaccggtaa gagccacacg tccctgtgcg aggaacagcg cacgctggca gagattttcg
    15241 atgatcggca aattgtggct gaccaccaac accgtccgac cgccccgact ggcctgccgc
    15301 atcttcccta aacacttctg ttgaaaaccc gcatcgccta cggccaggac ttcgtccacg
    15361 ataagaatgt ctggctcaaa atgggccgcg acagaaaagg ccaagcgcac atacatcccg
    15421 ctcgaatagc gtttcaccgg cgtgtcgata aactcctcga cgcccgcaaa atcgatgatc
    15481 tcatccaact tggcggtgat ctcggcccgg cgcatcccga gaatagaccc attcagataa
    15541 atgttctcgc gccccgtcag ctcagggtga aagccagtgc cgacctcaag gagcgaaccg
    15601 acgcgaccat agatatcggc tgtccctgac gtgggcgccg tgattctgga caggattttg
    15661 aggagggtac ttttcccggc cccgttatgg ccgataatgc cgaacacctc ccccggcttc
    15721 acatcaaagg agacatcagt gagagcgcaa aactctcttc ccttcccggt atcatcggaa
    15781 cgacactgct tccaccagga gagcgcagcc gcgaggcgat cacgaagcgt atcgtgacgc
    15841 gcctgcaggc cgagggaata gcgttttgtc aggcgatcga ctgagatggc gacgttgccc
    15901 ataagtccgc atgtagtgga tatacgatat ttcgctccac ttatgtgtca cacattcgtc
    15961 ttcagatcac ctcggacttt ccctagcaga tgggtggatg gattaagcgt gagtcgcctc
    16021 aaccagggat ctattttgtt tccaccgccg ttccatacac ttgggtgcac gcacgagaaa
    16081 acagaatgaa gtattgaaaa tagccgtcca ccgtgacctc aaccattgcg tcagccaagg
    16141 gtttcgtgcg taacgcatcc tcgacggcat tgcgcatctc attcccgccg gtcacgggga
    16201 tcaatccgag aagatggtag acacaatcct gcccacgcac cttgcccagt tcggtatatc
    16261 ctcccggagc gagcggcttg gttgaaggcg cgatgcctcc cggatgatgc atgcatcccg
    16321 cggtgagggc tcccaccgcc aacatgacga ccatccaccc acgcctagac cagttgctca
    16381 aacgttgact catcatgagg ttctactcct ttcatgcgca tagccttcac gacatgcagt
    16441 gtgacatcca cgtcggacat accgttgtga ggatgtatga ggaagttggt actgcaagga
    16501 accggcggag tacggcgagc acgtttcccc atcttgcaca gatagccctt cagcctcaac
    16561 cctaaattgc gacggcctag cacatgatcg aatgtgcgac atcctctcgc gggctgcttg
    16621 gcagggcacg tcgccgccgg aactccaaat ggaggtatta cggaacagca gaaccttacc
    16681 ctcgccaccg agcacatcat gggcaatttc attgcctgtc agggaatacc tgatagtatt
    16741 tattcacgga acatgagacc ttcgccggct gccggatgat ggcggtgtga gccgatcaca
    16801 ccagagaatg ttccggcgtg ggagcgcacg cctctcgcag agtgcggctg tataccttgg
    16861 gcagaaaact cgtcatgatc actgcgtcgg gcgcggtgat cctcatactc atcggcctgc
    16921 tcctggggtt gggtgaggtg atcattcgtt ccgttcacct cattcgagac ggcattcctt
    16981 tttttgaaag caacgcaggc gggcgaatcg gtcccattac cctggatcag gacctgggct
    17041 ggaaggccac tgagcattat caggaagcct tggtggaaaa gaccaagaac ggcaccctgt
    17101 acccggtccg ccgctctcaa acgcaatatg gctttcgcag tttcggcgat gtgtcgtccc
    17161 gccgccccaa aatgttggtg atgggcgatt cattcaccca tgccaccgcg gtctcagacg
    17221 accggaccta ccacgcttta ttatccaaac tgctcgatgt cgaggtcttt gcctatgggg
    17281 caggaggcta tggcacgttg caggaatatc tcgtgttcga ccggtacctc gatatcgttc
    17341 gcccggatgt catcctgtgg caatactgca tcaacgactt catcaataac gacaatgagc
    17401 tcgagcgcct cagccgcgtc aacaacaatg gctgggtgcg accctactgg cgcaacggca
    17461 ccatccaact cctctctccg aaggaatcat cgcttcagat acgagactgg atcaatcgcc
    17521 acagccgatt tctctatttc gtcgtcacca ggctggatcg tctgcgagcc gcaaatacgc
    17581 gggatacggt tgaagtggac atcgaagcgg aaggcatgcg acatgccggg ttcgctcgat
    17641 cggtcgctgt cacggatgac ttgatgggac gagttcgggc acgggcgggt acgcggccga
    17701 tcatggcatt taattgcacg gaggccgaac cttacagcca ggcttttcgc gatatttccg
    17761 ggcaccatgc cattgcctat tggggcgatg tggctcaggt ggttcaagac gcggacacac
    17821 gcggggagga tgtatttgcc gccgatggaa gccactggaa cgagcggggg cacgaactgg
    17881 cagcccaggc gctggcgaaa catttcaaga cagcactccc gcccgtaccg cgcccctgac
    17941 gtcgcctcac ctatcgcagg cggacgatgt ctttcatcca acgtacccca ccattgcgac
    18001 tattcccgtc gcttggagcc cctggtgcga gacgctgact tccgtcgaga cgctgaggtg
    18061 gcccgtttcg aaccggctgc aggcaccttc acaccggctt ttctcgcctt cgaaaggccg
    18121 atcgcaatgg cctgctttc
//
LOCUS       DAOQPD010000081        17966 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1570_length_17966_cov_22.230250, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000081 DAOQPD010000000
VERSION     DAOQPD010000081.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 17966)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 17966)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17966
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1570_length_17966_cov_22.230250"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..2466
                     /locus_tag="PK063_15355"
     CDS             <1..2466
                     /locus_tag="PK063_15355"
                     /inference="COORDINATES: protein motif:HMM:NF012485.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secretin N-terminal domain-containing protein"
                     /protein_id="HMZ98476.1"
                     /translation="CGIVQSEKLIVACVSVWYTKEVVTLLIRYMQSPFPSTRVIIEGN
                     RLRRLSMVVSWWACCLALTACGTFASPDVKRGDQHLAAGNWEEASVAYRQALKDDPFE
                     PSLQNKYRISRERAAAAHDERGRQLLKDRQFDQAAEEFKRALTIEPTSKEYEAGLTEA
                     LRLKESRDRYREAERLAQLGRVTEAMTGYMRAVELDPTYKDALEGVARLSAEQHAADR
                     DDRQKQPVTLQFRNAGLKEVVEALGKAAHVNFVFDKDVRNDPITVSLEEKPFDEALSL
                     VLNSNSLFAQKAGPTLFIISPNTKQKQEQYQDLMIRTFYLSSAKAKDMVALLKSMLDV
                     KHIHGNEALNTIVIRDQPEKVELAEKIIQANDREDSEVLFDVEVLEVNRTVDQQYGLN
                     YPKQIGAGLVPPGFTGTIAGDLAQQFTYRNLASLGQDSYLFKVPTNVQLDFFKQITDA
                     KTLAAPKVRVLNNKKAEVNIGDKQPILLSTTNVLPGQAATGAVPTTSTVTSIEFRDTG
                     VKLTVEPNIHLANELSLKMKIEVIRLGDTVLLQQSPPITQFKFGNRSAETMLNVRDGE
                     TIILGGLLQEEDRRTKVTIPWIGDIPYLGNLLSSFKTQRVTTEVILTITPHIVNSLRI
                     PGPQGQAFWSGTESVYSTSPLFAMQPKPISARVAVPAAAGSAIEKSGSKKSKMNAASS
                     DAVSPRLQLSMQPADATVQMEKEIRVDVVATQAQGFDTETFTLEFDPKILEFRDATLG
                     EVLGTEAGKAPVAATSSSTEGIVELRLHRSSTATKDEGRLLRLTFLAKSPGVSPVRLQ
                     MAKHPGQDLPEGTGEASGVVRVR"
     gene            2463..2969
                     /locus_tag="PK063_15360"
     CDS             2463..2969
                     /locus_tag="PK063_15360"
                     /inference="COORDINATES: protein motif:HMM:NF019575.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HMZ98477.1"
                     /translation="MKQSGVTLLELLVTLTILTILASVALPFTKVSTKRTKEIELRQN
                     LRVIRAAIDAFRLEWARDGDTLIGPACVKNRLSCKDVTGPYGYPKSLDALLGVKLTGE
                     QATVRGTTIRRYLRSIPMDPMTGAADWRLRCYRDPASVKDWCGEDIYDVTTQSQELAL
                     DGTKYREW"
     gene            2944..3351
                     /locus_tag="PK063_15365"
     CDS             2944..3351
                     /locus_tag="PK063_15365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HMZ98478.1"
                     /translation="MVRNTESGRRAWVSSSAHGFTIIELMIVVTIVGILATLAVPSYH
                     AAIIKAKEGALRQDLFSLRDVIDQHRADKGKYPESIQALVSAGYLRRVPTDPLTGATT
                     SWQEMVDEAEGGMVDVFSGSELVGTNGVPYNQW"
     gene            3365..4195
                     /locus_tag="PK063_15370"
     CDS             3365..4195
                     /locus_tag="PK063_15370"
                     /inference="COORDINATES: protein motif:HMM:NF013630.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HMZ98479.1"
                     /translation="MIQPHVPARRKGVGLRLGCWLAALLLCESWGGCAKVTPNHEPAP
                     SDLQVAADTLKVAVREAQRTAAELRTELEEQRKELADAQVARAQLQGMLRETERRLTE
                     ARQIIELQREELTSARDERERLAQAVHPFTGHVKASSAPAPSRSKRSPAAQGAAIPGS
                     VDTREMRDDNSLVEQEPAAPQPLPLHREATDSSTAQASAVRVDPLPNRKAVGRTIVVQ
                     GGDTLWGLARRHKVEVAVLRALNGLSGDRILSGRKLRLPESEAQHAAVQPAAVDVVVQ
                     "
     gene            4238..5452
                     /locus_tag="PK063_15375"
     CDS             4238..5452
                     /locus_tag="PK063_15375"
                     /inference="COORDINATES: protein motif:HMM:NF012694.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HMZ98480.1"
                     /translation="MAVFSYRAARADGTTFEGHIEGDDEHVVRAKLEADGVLVFRLSR
                     SGTGFGVPGLSASRWGKLPLQDFLVFNQELLALIKAGLPVLRVWDLLIDRTQRAPFRE
                     ALKAVRQDIRGGASASEALAKHSTYFSDLYLATIRAGEQSGNLAEVLQRYIAYLKLMI
                     SLRQKVTKALAYPGFLVVVGVAVVGFLLSYVMPTFISVYGESSANLPTPTRLLISVIH
                     MGEAQLIPVAIIVIVATVMGRAWYQTSAGRLSVDRNLLRLPLLGTILVEHHTIQLTRT
                     LATVLAGGTPIVEALEIARGAVSNRFVSRGLVSAVNEIREGSTLAAAIERPKILPKLA
                     IEMLSVGEETGSLEPMLRDVAEFYEGDLDVRLSQLTTWIEPVLLLVMGLLVGGIVIIM
                     YLPIFQMAGTIQ"
     gene            5516..7249
                     /locus_tag="PK063_15380"
     CDS             5516..7249
                     /locus_tag="PK063_15380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase, T2SS/T4P/T4SS family"
                     /protein_id="HMZ98481.1"
                     /translation="MAMQRHLTRPSLADVLVREGILPRRTVDQVVARLGGSTTALGHT
                     LVEDGTISEMQLAQALAAQYGLPYDALTGFRVDSEFYHTISVKLMRRHPFVPLKDEAG
                     ILTIAISDPQNLLGLDELEILLNRPLHYVVSSKNAIQAALERSEGSSQALRELEAEYR
                     SVLVKEDERGEEVLTVDHFGEDQSPVVKLLDTIMLSAMQRRASDIHIEATDRATTVKF
                     RVDGILVSAMDPLDVKLHPPLVSRLKVMSDLDIAERRVPQDGSFRMRLDRKTVDFRVS
                     ILPSVFGESVVIRILDREAITTGVSTLRLDRLGFNPEDLKRFRRAITRPYGMVLVTGP
                     TGSGKTTTLYAAISEMNIQEDKLITIEDPVEYQLPGVVQIPVNEKKGLTFARGLRSIL
                     RHDPDKIMVGEIRDAETAQIAIQSALTGHLVLTTVHANNVFDVIGRFASMGIDSYNFL
                     AALTCVLAQRLIRVICPDCRHQVTLDQALAEESGLDYDEFKTSPFYEGKGCSECHDTG
                     YRGRKCITEFLDLTDEIKEMILADRALSEIRYRAVTDGMITLRQSAVKKVLAGETTLR
                     EINRVTFSEER"
     gene            7253..8260
                     /locus_tag="PK063_15385"
     CDS             7253..8260
                     /locus_tag="PK063_15385"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98482.1"
                     /translation="MWDWITSRPQYCLKIGAHDLAWAEVHRNWRGRPRYQCVVSALPD
                     GILRLSPLEQNVVSPHELESHIRAIAGSATTQAPGRSSTPGVPRAATVILPDLAVRLA
                     VVRLQDLPWSSDERDALVRWRLGQEQLLSLSGAKVFSQVLSEPGVSGDGPCTVLAVVV
                     QEAVLSQYEAVCEAAGLIPQEVDVASLRLFNLWSHGAWRTAGSTADFLWVNATEGGVT
                     AFIFHKGVLVFLRSKLQGGVGSSGIWPAGSEQLGINRIVQECADSIYACQQQTPELAI
                     SQTILIADDALGPGLRQQLEKGLGVPVQELDWERVQQFGGGPIAGPRTSAAMPAIAGV
                     V"
     gene            8264..8887
                     /locus_tag="PK063_15390"
     CDS             8264..8887
                     /locus_tag="PK063_15390"
                     /inference="COORDINATES: protein motif:HMM:NF016992.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HMZ98483.1"
                     /translation="MMLDNLASVLRDVASRIGQPSARSGVFTINLSSRYRWYLAPARL
                     LIMVLAGVIGVAILWDISQSWLVWQDVQARESALLQVQERDNELLKEAQQEGLDLSEA
                     ALQLLPKEIEFANHLIEKRSFSWTRFLTELERAIPQRIAVNSIRLDPANATIMLTGSA
                     RALEDVTTLTVMFQDHPQFKDPVLGQHRVMGNGLVEFDLTLRYRNRS"
     gene            8890..9459
                     /gene="pilO"
                     /locus_tag="PK063_15395"
     CDS             8890..9459
                     /gene="pilO"
                     /locus_tag="PK063_15395"
                     /inference="COORDINATES: protein motif:HMM:NF016253.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0043107 - type IV pilus-dependent motility
                     [Evidence IEA];
                     GO_process: GO:0043683 - type IV pilus assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HMZ98484.1"
                     /translation="MFPGLDRLQLTGRQPYAPILPWVAFVVVLAIVSYGIHALVLGAA
                     EEEQVRLEAESVKARQQLNRHREAKKAKADLQRVWAVLPLFRDFAPLALGVTEEAKRD
                     QVTLPALSYKTEKTSVPDATKAVLQGTVTGRYEDLRRFLYNLESAQELLFIEDLNLVR
                     SGNIQDQQLTFNIRISTYLRGEHLQSPTP"
     gene            9465..10178
                     /locus_tag="PK063_15400"
     CDS             9465..10178
                     /locus_tag="PK063_15400"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98485.1"
                     /translation="MNRVSKNQGMLLLTLVVFWIGLLIWQFDHSNEQARVPLTHVSGQ
                     RATSKTPQAASSGNLQVHLERLAAIKGQREATFSTPRNIFASLLPQVEPVAVPPPAPR
                     RGRSRGPAKAAPPPVLEPLGEPQEQTAAEEEQEPVVEGPKGPTPEEIERLRIATELNQ
                     YRYVGFMAVGGGSQKKKNMAVVVKNDEMHVVQVGEVIGGEVLVKDVSLKEITLQDVGS
                     KITQVIPVTDDPGAGGQPN"
     gene            10240..10794
                     /locus_tag="PK063_15405"
     CDS             10240..10794
                     /locus_tag="PK063_15405"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98486.1"
                     /translation="MFSIVLIGISVSAAARQWTVMVQREKEADLMAKGIEIQNALALY
                     SASMKIGRIMTTEIYPQSLAELTRTPKPFLRRVYQDPISGGDWEYMRAPTGGIMGVRS
                     KSKVKPIKERDFPLAVRHFEGRKTYHDWMFQHPNPSSQSMLMPPMMGLAPGTMPTHPG
                     AQGAVPGGGTPQGAPLMPGAPRNP"
     gene            10917..12230
                     /locus_tag="PK063_15410"
     CDS             10917..12230
                     /locus_tag="PK063_15410"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HMZ98487.1"
                     /translation="MEQDLTESPAPELEAPVEVLSPEDYVMGLVKSAKKAAGRLSTLS
                     AAVKNEALEAMAEGLVAHEAELLAANEKDLEQFDATPERKALGDRLRLTAERIRDMAA
                     GLRDVARLPDPLGEMPKMWTRPNGMQVGRMRVPIGVIGIIYEARPNVTADSAALCLKS
                     GNVCLLRGGSEALHSNTAIAKVLSESAEKAGVPAGAITFVDRPEREIVQLLLKQDQYI
                     DLIIPRGGDSLMKTIAEHATIPVLKHDKGVCHTYVDADADPKVAEHICMNAKVQRPST
                     CNAMETLLVHHSIARTWLPHLIKQLTAAKVEVRGCAKTCQLCPEVKPAVEDDFGHEFL
                     DLILAVKVVKHMDEALEHIATFGSRHTEAIVTKDYSRAMRFLREVDAGAVLVNASTRL
                     NDGYQFGLGAEIGISTSRLHARGPMGLEELTCSKFVVLGSGQIRE"
     gene            12231..14009
                     /locus_tag="PK063_15415"
     CDS             12231..14009
                     /locus_tag="PK063_15415"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98488.1"
                     /translation="MPVDVSLQEILSRPGTLAFPSNLADAPRLPASSASCLRLPTGHL
                     VVYGSHGRRILATDPDGYPLHECEWESVNGRLRLVRSRVHLDWGAWVGLIPGGLVNTM
                     TLDLSRKPGWQRLRADDLRSMAAQAMHVPLDEVRFFYSDQDMTIDAKGRATIRHRKDA
                     IYHLPDGTFDTEQFMACMGAMHWEAIDFLPVVELFLSLLPGTGSALFELIRGLYDDQN
                     RGQVAPRPLRYRGIPTYPSEAAYRLFSNFFSPHLTDGSDPFPVFMDTPRSHLVTWTPV
                     PDPPRRHVDLSQKLCVTIQGRRMLKATRWDDPAGLSYQPFDQRGLAPCQRGLMVRQGQ
                     LLLTDGDMTQAIALPEGWGRVDEPAGAGAALPAREWKTVFGGNPPHVDPGAAFGAVLL
                     YPNDEREIGELATQPFVADYLQDLIEQDRPLAAKVSHAEHVLISGLDAAITTCIGSDR
                     ARAYTVLYDHAAFAQRQAQMWWNLLVRAQRLEWLTRVQMRPRGAEGERRELYDLAYEW
                     TPFSLYDKPESIHHRVQQLASHLSLGAVAFIIGPPTVADSCRTAGVQLQSITPVASLP
                     TFRMHQSVLPRAQLKPGIMLYQIARS"
     gene            14268..14702
                     /gene="gspG"
                     /locus_tag="PK063_15420"
     CDS             14268..14702
                     /gene="gspG"
                     /locus_tag="PK063_15420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014449838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system major pseudopilin GspG"
                     /protein_id="HMZ98489.1"
                     /translation="MNASDGFSFIEVMIVVVILAILATLLIPRVMGRTEDAKRAAAKA
                     QISNIESALQLYKLDNGNLPSTEQGLKALVERPGSGPPAPNWKAGGYLPKVPVDPWGT
                     PYKYTVPSSQGAEFEILSFGADGTPGGDGKNADIVSWDLDRN"
     gene            14844..>15669
                     /locus_tag="PK063_15425"
     CDS             14844..>15669
                     /locus_tag="PK063_15425"
                     /inference="COORDINATES: protein motif:HMM:NF020252.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDOD domain-containing protein"
                     /protein_id="HMZ98490.1"
                     /translation="MRRVFFVDDAPEILKHLQRTLAPMQSEWTMEFFSSAKSALAAIC
                     QAPCDVVVSDMTMPGMDGAQFLTEVRNVSPQAIRIILSGDQSPVNYLRSASVAHRFLQ
                     KPVDVEVLKANIAQAEALRAVLANPALRTLVSEIKALPSLPSIYQDLMQEMQSPQASL
                     KKASRIVAKDLGMVTKILQLVNSAFFGLRTHVSDPEQAVALLGFETIKSLVLSSQVFA
                     QFDQNRLPGFSLDALWRHAMLTATCARRIAKDTGASQPVIDEAFTAALLHDVGVLVL"
     assembly_gap    15670..15769
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <15770..16980
                     /locus_tag="PK063_15430"
     CDS             <15770..16980
                     /locus_tag="PK063_15430"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98491.1"
                     /translation="MNHRANGYLVSIEPDEPKMEFILPLKPTSFRGNAGYVFKNYDRL
                     KQAGVTEFQLTLGLVFADLPLQIFDINQIGVDGNYAPWLAHVDRIIDQVMDRRLSVLW
                     DIYNEPDLATLPINDNDRLKEGWRLAYQRIKQRIPGAQIVGPSISRYRLLKPFLEWSH
                     DHNVFPDVVAYHEYDDPSHAPALVEDLRSYLRGRGIVRPISVNEILGQESWTLAGYTV
                     GVIAAYERANILSAMRSCWPDPQDMSRDRVENTCDNPTLDGLLYVDRQSKRPGWHIYK
                     AYAEMDGVRLATMTDSPKLHALASFDKASGTLQLLLGKYEDYSTQDTTVMLKNAARVF
                     SGGQGKNLFLCAEQIPDTGSGPLASTVVTMDRTLPLPDNDISFTLPQFYHSDAYRVRI
                     SPTSGCKPRD"
     gene            17258..>17966
                     /locus_tag="PK063_15435"
     CDS             17258..>17966
                     /locus_tag="PK063_15435"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98492.1"
                     /translation="MQDQAAVCTDTPTNQQAGQPPTPQNAVRSWLLRAVALFIKPAHF
                     FATFDDLARPVVLLVATLCLGVASMVDRIEQHILRAEMGQGVSGWSELSPWLLHSWGT
                     LWIALLVCGALNVPLFWYLGGWWYRLRLKWSGATALDSLRPRLLFVYSSLVYALPVVL
                     VMIGETLLFPNYRLARDAEGSWTLIFVLLSFWSVVVSYCGATRTFALARRKALLWFLL
                     LPWTLYAVELGLWMWLFE"
BASE COUNT         3669 a         4899 c         5482 g         3816 t
ORIGIN      
        1 tgcggcatcg tccaaagcga gaaactgatt gtcgcgtgtg tgtcagtttg gtataccaaa
       61 gaggttgtca ccttgttgat cagatatatg cagtcaccct tcccttccac acgcgtcatc
      121 atcgaaggta atcggcttcg ccggctgtcc atggtcgtca gctggtgggc atgctgcctg
      181 gcactgactg cctgcggcac gtttgcgtct cccgatgtca aacgcgggga ccagcatctc
      241 gcggcaggaa attgggagga ggcgagcgtt gcgtatcggc aggcactcaa ggatgatccg
      301 ttcgaaccgt cgctacaaaa caagtatcgc atttcgagag aacgtgccgc cgcagcgcat
      361 gatgaacgcg gccgacaatt attgaaggat cgccaattcg accaggccgc cgaggagttc
      421 aagcgggctc tcacgattga accgaccagc aaagagtatg aagcaggctt gaccgaggcg
      481 ctgcgattga aagaatcgcg tgaccggtat cgggaagcag aacggttagc gcaactaggg
      541 cgtgtcaccg aagccatgac cggctatatg cgagccgtcg agttggaccc cacctataag
      601 gatgcgctcg aaggcgtcgc ccgtctgtcc gccgaacagc atgcggccga tcgtgatgat
      661 cggcaaaagc agccggtgac cctgcaattt cgcaatgcgg ggctcaagga agtcgtagag
      721 gcgctgggga aggccgctca cgtcaatttc gtgttcgata aggatgtgcg aaacgatccc
      781 atcacggtct cgctcgaaga aaaacccttc gacgaggcct tgtcgctggt gttgaacagc
      841 aacagcctgt ttgcgcagaa ggccggcccg acgctcttca tcattagtcc caacaccaag
      901 cagaagcagg aacagtatca ggacctgatg atccggacct tctatctgtc gtcggccaag
      961 gcgaaagata tggtggccct cctgaagtcg atgctggatg tgaaacacat ccatggcaat
     1021 gaggccctca ataccatcgt cattcgtgac caaccggaaa aggtggagtt agccgaaaaa
     1081 atcattcagg ccaacgaccg cgaggattcc gaggtgctgt tcgacgtgga agtgctggag
     1141 gtcaaccgga cggttgatca acagtacggg ctgaattatc ccaagcagat tggcgcaggg
     1201 ctcgtgcctc caggatttac tgggacgatc gccggcgacc tggcgcagca gtttacctat
     1261 cgcaatttgg ccagcttggg acaggacagt tatctgttca aggttcccac gaatgtgcag
     1321 ttggatttct ttaagcaaat caccgatgcc aagacgctcg ccgcgccgaa agtgcgagtg
     1381 ctgaacaata aaaaggcgga agtgaacatc ggcgataagc aaccgattct gttgtcgacc
     1441 accaacgtgt tgccggggca agccgctacc ggcgcggtgc cgacaacctc gacggtgacg
     1501 tcgattgagt ttcgggacac cggtgtgaag ctgacggtgg aaccgaacat tcatctcgcg
     1561 aacgagctgt ccttaaagat gaagatcgag gtgatccgcc tgggtgacac cgtcctgctg
     1621 cagcaatctc caccgatcac acagttcaag ttcgggaatc gctcggcaga gaccatgctg
     1681 aacgtgcgtg atggagaaac catcatcctc ggcggcttgc tccaggagga ggatcgtcgc
     1741 accaaggtga ccattccatg gatcggcgac attccgtatc tgggaaatct tctgagttcc
     1801 ttcaagaccc agcgggtgac gaccgaagta atcctgacca ttacgccgca tatcgtcaat
     1861 tcgctccgca ttcccgggcc gcaagggcag gcgttttggt caggaactga gtccgtgtac
     1921 tccacgtcgc cattatttgc catgcaaccg aagccgatct cggcgcgggt ggcggtcccg
     1981 gcggcagccg gatcagccat tgagaaaagc gggtcgaaga agtcaaaaat gaatgccgcg
     2041 agttcagacg cggtctcgcc cagacttcag ctgtctatgc agcctgcgga cgccacagtc
     2101 cagatggaga aagagatccg tgtggatgtg gtggcgactc aggcccaagg gttcgatacg
     2161 gagaccttca cgctagagtt tgatccgaag attctcgaat ttcgagacgc gaccctcggt
     2221 gaagtgttgg gaaccgaggc cggcaaagct ccggtggccg cgacatcatc ttccacggag
     2281 ggcattgtgg agctgcggct gcatcgctct tcgactgcca ccaaagatga aggccgcctg
     2341 ttgcgattga ccttcctcgc caaatccccg ggtgtctcgc cggtgcggct gcagatggcc
     2401 aaacatcccg gccaagacct gccggaggga acgggcgaag cctcaggagt ggtgagagtg
     2461 cggtgaaaca gtccggcgtg acgttgcttg agctgctcgt gaccctgacg attctcacca
     2521 tccttgcctc ggtcgcgctg ccgttcacga aggtctccac gaaacgcacg aaggagatcg
     2581 aacttcggca gaatctccgg gtgatacgag ccgcgattga tgcctttcgc ctggaatggg
     2641 ctcgtgacgg tgacacgctt atcggtccgg cctgcgtcaa gaatcggttg agttgcaaag
     2701 acgttaccgg cccctacgga tatccgaagt cgctcgatgc cttgctgggc gtcaaactca
     2761 ccggtgagca ggcgacggtg cggggaacga cgatacggcg ctatctgcgc tcaattccca
     2821 tggatccgat gaccggcgca gccgattggc gcctgcgttg ctaccgggac cccgccagcg
     2881 tgaaagactg gtgcggagaa gacatttacg atgttacgac tcagagtcaa gaactggcct
     2941 tggatggtac gaaataccga gagtggtagg cgcgcatggg tctcctcgtc agcgcacgga
     3001 tttacgatta tcgagttgat gattgtggtg acgatcgtag ggattcttgc cacattggcg
     3061 gtgccgtcgt atcacgcggc gatcattaaa gcgaaggaag gggccttgcg tcaggatttg
     3121 ttctcgttac gcgacgtgat cgaccaacat cgcgccgaca aggggaagta tccggagagc
     3181 attcaagccc tggtatcggc cggttacctc aggagagtcc cgaccgaccc gttgaccggg
     3241 gcgaccacat cgtggcagga gatggtcgat gaagccgaag gcgggatggt cgatgtgttt
     3301 tcaggctccg aactggtcgg aaccaatgga gtaccctaca accaatggta aggcaatgaa
     3361 catcatgata cagccacatg ttcctgcgcg acggaaggga gttgggttac gtctcggatg
     3421 ctggttggcc gcattgctcc tctgtgagtc ctggggaggc tgcgcgaagg tcacgcccaa
     3481 tcacgaacca gccccctcgg atctgcaagt ggcggcggac accctcaagg tcgcggttcg
     3541 cgaagcgcag cggacggcgg ctgagttgcg gacggaactg gaggaacaga gaaaagaact
     3601 ggccgacgcg caggtggcgc gtgcacaact acagggcatg ttacgggaaa cagagcggcg
     3661 actgacggag gcccgtcaga tcatcgaatt gcagcgtgaa gagctcacct cagctcgcga
     3721 cgagcgggaa cgattggctc aggcggtcca cccctttacc gggcatgtga aggcatcctc
     3781 tgctcctgct ccatcgcgca gcaagaggtc acccgctgcc cagggtgcgg cgattccggg
     3841 ctccgtcgac acgcgggaga tgagggatga caattccctc gtagagcaag aaccggcggc
     3901 tccgcagcct ctgcctcttc atcgcgaggc cacagactca tcgacggctc aggcatcagc
     3961 cgttcgtgtc gacccgcttc caaacagaaa ggccgtgggt cggacgatcg tggtgcaagg
     4021 cggcgatacg ttatgggggc tcgcgcgccg gcacaaggtt gaagtcgcgg tacttcgcgc
     4081 actcaacggt ttgtcaggtg accgcatcct gtctggacga aagcttcgtt tgcctgagtc
     4141 ggaagcgcag catgcggctg tgcaaccggc tgcagtcgat gtcgtggtgc aatagcggtt
     4201 gaagattatc gcgtgatgtg ccgagccgaa tgaactcatg gctgtttttt cctatagagc
     4261 ggctcgcgcg gatggaacga ccttcgaagg ccacatcgaa ggcgacgatg agcatgtggt
     4321 ccgcgcgaaa ctcgaagcag acggcgtcct ggtctttcgg ctctcccgaa gcggaacagg
     4381 gtttggtgtg ccgggcctgt ctgcgagccg ctggggcaag cttccccttc aagattttct
     4441 cgtgtttaat caagagctgc tggccctaat caaggcgggg ctcccggttc ttcgggtgtg
     4501 ggatcttctc atcgatcgca cgcagcgcgc gccgtttcga gaagcgctca aggccgttcg
     4561 tcaggatatt cgtggcgggg cctcggcatc cgaagccttg gcgaaacact ccacctattt
     4621 ttcggatctc tatttggcca ccattcgcgc cggcgaacag tcggggaatt tggcggaggt
     4681 gttgcaacgg tacattgcct acttgaagct gatgatcagc cttcgccaaa aggtgacgaa
     4741 ggccttggca tatccgggtt ttctcgtcgt ggtcggcgtt gcggtggtcg gatttctcct
     4801 gagctacgtc atgccgacct ttatctctgt gtacggagaa tcgtccgcaa atctcccgac
     4861 gccgacgcga ttgctcatct ccgtcattca tatgggagag gcgcaattga ttccagtggc
     4921 cattatcgtc attgtagcaa ccgtcatggg gcgggcttgg tatcaaacat cggccggacg
     4981 gttatcggtg gaccggaatc tgttgcggtt gcccttactc gggaccattc tcgtggagca
     5041 tcatacgatc caattgacgc ggacattggc gacggtgttg gccggcggta cgccgattgt
     5101 ggaagcgctg gaaattgcgc gcggagcggt ctcgaaccgc ttcgtctcac gcggactggt
     5161 gtccgcggtc aatgagatcc gtgaaggcag cacgctggcg gcggccattg agaggcccaa
     5221 aattttgccc aagctggcca tcgaaatgct gtcggtcggg gaggagacag gctcgctcga
     5281 gccgatgctc agggatgtgg ctgaatttta tgaaggtgat ctcgatgtgc ggctcagcca
     5341 gttgacgacg tggatcgagc cggtcttgtt gctggtcatg gggttgctcg tcggcggaat
     5401 tgtcatcatc atgtacttgc ccatttttca gatggccgga acgattcaat aatgcggcgg
     5461 ggtagacctc atcgttcagg agcctggagt cccatcaggg gtggagattt gtagtatggc
     5521 catgcaacgt catctcaccc gcccgtcgtt ggccgatgtg ttggtgcgcg aagggatcct
     5581 tcctcgccgc acggtcgatc aggtcgtggc ccgccttgga ggcagcacca ccgcgttggg
     5641 acacacgctg gttgaagacg gcaccatttc agagatgcag ttggcgcaag cgttagccgc
     5701 gcaatatggc cttccttatg acgcgctgac cggcttccgg gtggattcgg agttttatca
     5761 caccatttcc gtcaagctca tgcgccgtca tcccttcgtg cccctgaaag acgaggcggg
     5821 gatcctcacc attgcgattt ccgatcccca gaacctgctt ggactggatg aattggaaat
     5881 tttgctcaat cgcccgttgc actatgtagt gagttcaaag aacgcgattc aggccgcact
     5941 ggagcgcagc gaaggatcga gtcaggcctt acgtgaatta gaggctgagt accggtcggt
     6001 tctcgtcaag gaagacgagc ggggcgaaga agtcctgacg gtagaccatt tcggcgagga
     6061 ccaaagcccc gtcgtcaagc tgctcgacac gatcatgtta agcgccatgc agcggcgggc
     6121 gagcgatatt cacattgaag ccacggatcg tgcgacgacg gtgaaatttc gcgtggacgg
     6181 gattctggtc tcagccatgg acccgctgga tgtgaagctg cacccgccgc tggtctctcg
     6241 cctcaaggtc atgtccgatc tggacatcgc agagcgccgg gtcccgcaag acgggagttt
     6301 ccggatgcgc cttgaccgga aaacggtcga cttccgcgtg tcgattctcc cgagcgtgtt
     6361 cggcgaatcg gtcgtgatca gaattttgga ccgcgaggcg atcaccaccg gcgtctccac
     6421 cttgcggctg gatcggctgg gattcaatcc tgaagatctc aagcggttcc ggcgcgcgat
     6481 tacgaggccc tacgggatgg tgctcgtgac cggtccgacg ggaagcggca agaccacgac
     6541 gctctacgcc gccatcagcg aaatgaacat tcaggaagac aagctgatca ccatcgaaga
     6601 cccggtggaa tatcagttgc cgggtgtcgt ccaaatcccg gtgaatgaga agaaaggcct
     6661 cacctttgcc cgcgggttac ggtccattct gcgtcacgat cctgacaaga tcatggtcgg
     6721 agaaatccgt gatgcggaga ccgcgcagat cgccattcaa tcggcgctca ccggccattt
     6781 ggtgttgacc acggtgcacg ccaacaatgt gttcgatgta atcggccggt tcgcatcgat
     6841 gggcatcgat tcctataatt tcctggcggc gttgacctgc gtgttggcgc aacgattgat
     6901 ccgggtgatt tgtccggact gtcgccatca ggtcacgctg gatcaagcgc tggcggaaga
     6961 gtccggtctc gattatgacg aattcaagac ctcgccgttc tatgaaggca aaggctgctc
     7021 cgagtgtcat gacacggggt atcgtggccg caagtgcatt accgagtttc tggacctgac
     7081 agacgagatc aaggaaatga ttctggctga ccgtgcattg tcggagatcc ggtaccgggc
     7141 ggtcaccgac ggcatgatta cgctgcgtca atctgcggtc aagaaagtgc tggccgggga
     7201 gacgacgttg cgcgagatca accgtgtgac gttcagtgaa gagcgataga cgatgtggga
     7261 ttggattacc agcagaccgc agtattgcct gaaaatcggc gcgcatgatc tggcctgggc
     7321 ggaggtgcat cgcaattggc gcgggcgtcc acggtatcaa tgcgtggtgt ccgcgttgcc
     7381 agatggcatc ctccggctat cgccattgga acagaacgtc gtgtctccgc atgaactgga
     7441 atcgcatatc cgcgcgattg ccgggtcggc gacgacccaa gcacctggcc gttcttccac
     7501 cccgggagtc ccgcgcgccg ccacggtgat tctgccggat ctggccgtgc gtctggcggt
     7561 tgtccgcttg caagaccttc cgtggagttc ggatgagcgg gatgcgttgg tgcgttggcg
     7621 attagggcag gagcagttgc tgtccttaag cggggccaaa gtcttctccc aagtgttgtc
     7681 cgaacccggc gtgtccggtg acgggccctg caccgtcctc gcggtggtgg tgcaggaggc
     7741 cgtgctgtcg cagtatgaag ccgtgtgcga agccgccggt cttatcccgc aggaagtgga
     7801 tgtcgccagc ctgcgcctgt tcaacctgtg gtcccatgga gcctggcgta ccgcgggctc
     7861 gactgccgat tttttgtggg tgaatgccac cgagggcggg gtcacggcgt ttatctttca
     7921 taaaggcgtc ttggtcttcc tccgttccaa gttgcagggt ggagttggat ccagtgggat
     7981 ctggccagcc ggctcagagc agttggggat caaccggatc gtgcaggagt gcgccgactc
     8041 gatttacgcc tgtcagcaac agacgcctga attagcgatc agccaaacca ttctaattgc
     8101 agatgacgcc ctgggaccgg gcttgcgcca gcaattggaa aaaggattag gcgtgcccgt
     8161 gcaggaattg gattgggaac gggtgcaaca attcggcggt ggtccgattg ccgggccacg
     8221 gacaagcgcg gccatgccgg cgatcgcagg ggttgtgtaa gtcatgatgt tggataatct
     8281 ggcatcggtg cttcgcgatg tggcctcgcg tatcggtcaa ccgtctgccc gcagcggtgt
     8341 attcacgatc aatctgagca gccgctatcg ttggtatctg gcgccggcac ggttgctgat
     8401 tatggtattg gcgggagtga tcggcgtggc catcctttgg gacatttctc aatcttggct
     8461 ggtgtggcaa gacgtgcaag cgcgcgaatc agccctgttg caagtccagg agcgggacaa
     8521 cgaattgctc aaggaggcgc agcaggaagg cctggacctt tccgaagccg ccctgcaatt
     8581 gctgccgaaa gagatcgagt tcgccaatca tctgatcgag aagcggagct tttcatggac
     8641 ccggttcctg acggaactgg agcgtgcgat tcctcagcgc attgccgtca acagtattcg
     8701 tctcgatccc gcgaatgcga cgatcatgct gaccggatcg gcgagggcgc tggaagatgt
     8761 gaccacgctg acggtgatgt ttcaagacca tccccaattt aaggatcccg tgttgggcca
     8821 gcaccgggtg atgggaaacg ggctggtcga gttcgacctc acgttgcggt atcgaaaccg
     8881 gagctaacga tgtttccagg cctcgatcgc ctacaattga ccgggcgtca accctacgcg
     8941 cccatccttc cctgggtggc tttcgtggtg gtcctggcca tcgtgagtta cggcattcac
     9001 gccctggtgt tgggtgcggc ggaggaggag caggtgcggc tcgaagccga gtcggtcaag
     9061 gcgcggcagc agttgaaccg gcacagggaa gccaagaagg cgaaggcgga tcttcagcgc
     9121 gtgtgggccg tcctgccgtt gtttcgggat tttgccccgc tcgccctcgg tgtaacggaa
     9181 gaagccaagc gggatcaggt cacgctgccg gctctgtcct ataagacaga gaagacgtcg
     9241 gtaccggatg ccaccaaggc ggtgctgcag gggacggtga ccgggcggta tgaggacttg
     9301 cgccgcttcc tctacaactt ggagtcggcc caggaactat tgtttatcga ggatctcaat
     9361 ctcgtccgct caggaaacat tcaggaccag caattgacgt tcaatatcag gatttcgact
     9421 tatttgcggg gagagcatct gcaatctccg acaccctgac gctcatgaac cgagtcagta
     9481 aaaatcaggg gatgctgttg ctgaccctcg tcgtcttctg gatcgggttg ctcatctggc
     9541 aatttgacca ttcgaacgaa caggcgcgag tcccgttgac ccatgtcagt ggacagcgag
     9601 ccacgagtaa gacgcctcaa gccgcttcca gtggtaattt acaagttcat ttggagcgct
     9661 tggccgccat caagggccag cgcgaagcca cgttttccac gccgcgcaac attttcgcca
     9721 gcctgctgcc ccaggtggag ccggtagcgg ttccgcctcc ggctccccgc cgaggccgtt
     9781 cacgtgggcc tgctaaggca gctcctcctc ccgtacttga gccgctcggg gagccacagg
     9841 aacagactgc cgctgaagag gagcaggaac ccgtggtaga agggccaaag gggccgacgc
     9901 cggaagaaat tgaacggctc cggatcgcga ccgagctcaa ccagtaccgc tatgtcggct
     9961 tcatggcggt tggaggagga tcgcagaaaa agaagaacat ggcggtggtg gtcaagaatg
    10021 acgagatgca tgtcgtgcag gtgggagaag tgatcggggg agaagtcctg gtcaaagatg
    10081 tgtcgttgaa ggaaattacg cttcaagatg tgggatcaaa aatcacccag gtcattccgg
    10141 ttacggatga tcccggcgca ggggggcaac ccaactaagc cggcgatggg gttgcggggt
    10201 cctctccgaa atgcccgggg tatcacctat ctggccttga tgttttcgat cgtcttgatc
    10261 ggcatttccg tttctgccgc ggctcgccag tggacggtga tggtccagcg cgaaaaagaa
    10321 gccgatctca tggcaaaagg gatcgaaatt caaaacgcgc tggcgttgta ctcggcctcg
    10381 atgaaaatcg ggcgcatcat gacgaccgaa atctatcctc agtctctagc cgaattgacg
    10441 cgcacgccca aaccattttt gcgacgagtc tatcaggacc cgatcagcgg gggagactgg
    10501 gagtacatgc gagcgcccac cgggggcatc atgggggtgc gcagcaagag taaagtcaaa
    10561 ccgatcaagg agcgtgattt tccgctggcc gtccgccatt tcgaagggcg caagacctac
    10621 catgactgga tgttccagca tcccaatccg tcttcccaat ccatgctgat gccgcccatg
    10681 atggggctgg cgcccgggac catgccgaca caccctggtg cacaaggggc cgttcccggc
    10741 ggcgggacac cacaaggcgc tcctctgatg ccaggggctc cccgtaaccc ttgacccgac
    10801 tccaaacccc acagtatcct gtcacgctat tgttttttcg cctacgttca ccatcttgat
    10861 cggtggatac ctttggcctc gggcctctgt atcgccaagc agcaggaatt cacgacatgg
    10921 aacaagacct gaccgaatcc ccggctccgg agctggaagc tcccgttgaa gtactgtctc
    10981 ctgaagacta tgtgatgggt ttggtgaaga gcgccaagaa ggcggcgggc cggctgtcga
    11041 ccctttcggc tgcagtcaaa aatgaagcct tggaggctat ggctgaaggg cttgtggccc
    11101 atgaggcgga gctgctggcg gcgaacgaaa aggatctcga acaattcgat gccacgcccg
    11161 agcgcaaggc gctaggtgat cggttgcgac tgacggcgga gcgtattcgc gatatggctg
    11221 ctggcttgcg tgatgttgcc cgcctgccgg atccgcttgg cgagatgccc aagatgtgga
    11281 cgcggccgaa cggcatgcag gtgggccgga tgcgggttcc catcggggtc atcggaatca
    11341 tttatgaggc tcgtccgaac gtcacggcgg actcggccgc tctctgtctc aagtcgggaa
    11401 atgtctgtct cctacgcggc ggatcggaag cgctgcattc caatacggcg attgccaaag
    11461 tgttgagcga atcagcagag aaggccggtg tgccggccgg cgccatcacc tttgtagatc
    11521 ggccggagcg tgaaatcgtc cagctgttgt tgaagcagga tcagtatatc gacctcatca
    11581 tccccagggg cggggattcg ttgatgaaga ccattgctga acatgcgacg attccggtgc
    11641 tgaagcatga taagggcgtc tgtcacacgt atgttgatgc ggatgccgac ccgaaagtgg
    11701 ctgaacacat ctgcatgaat gccaaggtgc agcgaccctc aacgtgcaat gccatggaga
    11761 cgctgttggt ccaccacagc atcgcacgga cctggcttcc gcatctcatc aaacagctca
    11821 cggctgcgaa ggtggaagtg cgtggttgcg caaagacctg ccagctctgt cctgaggtca
    11881 agccggcagt ggaggatgat ttcgggcatg aatttcttga tctcattctc gcggtcaaag
    11941 tggtcaaaca tatggatgaa gcgctggagc acattgccac attcggctcc cgtcatacgg
    12001 aagcgattgt gaccaaggat tattcccgcg ccatgcgttt cttgcgcgaa gtcgatgcgg
    12061 gtgcagtttt ggtcaacgcg tcgaccaggc tcaatgacgg gtatcagttc ggcctcggag
    12121 cagaaatcgg catcagcacc tcgcggcttc acgcgcgagg gccgatgggg ctggaagaat
    12181 tgacctgttc caagttcgtg gtgcttggga gcgggcagat ccgcgaataa atgcccgtgg
    12241 atgtctcgct acaggagata ctgagtcgcc ccggtacgct cgcctttcct tccaatcttg
    12301 ctgatgcgcc gcgcttgccg gcgtcatcag cgtcgtgcct tcgtctgccc acgggacatc
    12361 tcgtcgtcta tggaagccat gggcggcgaa tcctagcgac ggatccggac gggtatccat
    12421 tgcatgagtg cgaatgggag tcggtcaatg gccggctgcg tctcgttcga agccgggtac
    12481 atctggattg gggggcatgg gttggactca ttcccggcgg gctcgtcaat acgatgaccc
    12541 tggatctgtc caggaagcct ggatggcagc ggctcagggc cgacgatctt cgaagcatgg
    12601 cggctcaagc catgcatgtc ccgctcgatg aagtccggtt tttttacagc gatcaggaca
    12661 tgacgattga tgccaagggt cgcgccacga tccggcatcg caaagatgcc atctaccatc
    12721 tgcctgatgg gaccttcgac accgaacaat ttatggcgtg catgggggcc atgcattggg
    12781 aagccatcga ttttctgccg gtcgtcgagc tctttttatc gctgctgccc ggcactggct
    12841 ccgcactctt tgaattgatc cgtggcctct atgatgatca gaatcgcgga caagttgctc
    12901 caaggccgtt gcgataccgt ggtattccga cctatccgtc agaagcagcc tatcgtctgt
    12961 tcagtaattt cttttctcct cacctgacgg acggcagtga tccctttccg gtgttcatgg
    13021 atacaccgcg atcccacctg gtgacatgga ccccggtccc ggacccgccg agaagacatg
    13081 tcgacctgtc ccagaaattg tgcgtcacga ttcaaggtcg gcgaatgctg aaagcaaccc
    13141 ggtgggatga tccggcaggg ctttcctatc agcccttcga tcagagaggc ctcgcaccct
    13201 gccagcgcgg attgatggtc cggcaggggc agctcctgtt gaccgatgga gacatgacgc
    13261 aggcgattgc attgcccgag ggttggggac gcgtcgacga acctgccggg gcaggtgcgg
    13321 ccttgcccgc ccgtgagtgg aaaacggtgt tcggtgggaa cccgccgcat gtcgatccgg
    13381 gagcggcgtt tggtgccgta ttgctctatc ccaacgatga gcgggaaatt ggggaattgg
    13441 cgacgcaacc gtttgtcgcc gactaccttc aagatctcat cgagcaagat cggccattgg
    13501 ctgcgaaggt atcccatgcg gagcatgtgc tgatttccgg actcgatgcg gctatcacca
    13561 cgtgtatcgg gagcgatcgt gcgcgggcct atacagtgtt gtatgaccat gcggcgtttg
    13621 cacagcgtca ggcgcagatg tggtggaacc tcctggttcg ggcgcagaga ctagagtggc
    13681 tcacgcgtgt gcagatgcgg cctcgtggag cggaagggga acgccgggag ttgtacgacc
    13741 tggcatatga atggactccg ttcagtctgt atgacaagcc ggagtcgatt caccatcgtg
    13801 tgcagcaatt ggctagccac ctgtcgcttg gggcggtggc attcatcatc ggcccgccga
    13861 ccgtagcaga cagttgccga acggctgggg tgcagctgca gtcgatcacg cccgtggcgt
    13921 ctctgcctac attccgcatg catcaaagtg tgttaccccg cgcgcaactt aagcccggca
    13981 ttatgctata tcagatcgct cgctcctgat cggtggcctc atggcagatg cgtgtataga
    14041 gacgcgtacg agagcgctga caggagcatg tcacctcgga tttgaatgac acactcatag
    14101 acgttcctgt tacaattcaa aattggtcca cgcatggagc tcgcagcgag ccggatcggt
    14161 tgagagaagg agcagcacgt atggggtttt ttcgagaata caggaagtct acagggctag
    14221 accgcggtgc atcgtgcgag catcgttgct caggtcttgc aggaagactg aacgcgagtg
    14281 acggattttc gttcatcgag gtaatgatcg ttgtcgtgat cctggcgatc cttgcgacgc
    14341 tgctgattcc tcgagtgatg ggccggacgg aagatgccaa gcgggcggcc gcaaaggcac
    14401 aaatttcaaa catcgaaagc gcgctccaat tgtacaaact ggataacggc aacctcccgt
    14461 cgactgagca gggcctgaag gcgttggtgg aacggcccgg atcaggtccc cctgcgccga
    14521 attggaaggc gggtgggtat cttccgaagg tgccggtcga tccgtggggc actccctaca
    14581 aatacacggt gccgtcttcg caaggggccg aattcgagat tctctcgttc ggcgcggatg
    14641 gcactcccgg aggcgacggc aaaaacgccg atatcgtcag ttgggatctg gaccgcaact
    14701 agtgtctgga gtcaggcccg ctgagttccc tgccaatcca caggattgcc tcaattcccc
    14761 gtcgtagtgg ttcaatctga cttaagatcc tgcccctctc gaccgatgag gagaagagac
    14821 gaatcctgcc gggaggaggg cccatgcgac gcgtcttttt tgtcgacgat gcgccggaaa
    14881 ttctcaaaca cctgcaacgg acgttggccc ccatgcagtc cgaatggacg atggagtttt
    14941 tttcctccgc caagagcgcg ttagctgcga tctgtcaggc accttgtgac gtcgtggtgt
    15001 cggacatgac catgccgggg atggacggtg cccaattcct caccgaggtg cgcaacgttt
    15061 ctccacaagc gatccgcatt attctctccg gcgatcagag tccggtgaac tatctgcgct
    15121 cggcctcggt cgcgcatcgg tttctgcaaa agccggtgga tgtggaggtc ctgaaggcga
    15181 acattgcgca ggcggaggcc ttgcgggcgg tgttggccaa tcctgctctc cggacgctcg
    15241 tcagtgaaat caaggctctc ccgagtctgc cgtcgatcta tcaggacttg atgcaggaga
    15301 tgcagagccc gcaggcctca ttgaagaaag cctctcgcat cgtggccaag gatctcggca
    15361 tggtcacgaa gatccttcag ttggtcaatt cggcattttt cggcctccgc acgcatgtgt
    15421 ctgatcctga acaggcggtg gcgcttctgg gatttgagac gatcaaatcg ctcgtgctct
    15481 ccagccaggt ctttgcgcaa tttgaccaga atcggttgcc gggattttca ctggacgcgc
    15541 tgtggcggca cgcgatgctg acggcaacct gtgcccgccg gattgccaaa gacaccggtg
    15601 caagccagcc ggtcattgac gaagcgttta ccgcggcgct gctgcacgac gtaggcgtgc
    15661 tggtgttggn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnc gatgaaccac
    15781 cgggcgaacg ggtacctggt gagcatcgag cccgacgagc cgaaaatgga attcatcctt
    15841 ccgctgaagc ccacgagttt tagaggcaat gccgggtacg tcttcaagaa ttatgatcgg
    15901 ctcaagcagg ccggggtaac ggagtttcag cttacccttg ggctggtgtt cgcagacctg
    15961 cctctgcaaa tttttgatat caatcaaatt ggagtggatg gaaactacgc accctggctc
    16021 gcgcatgtgg atcgaatcat cgatcaagtg atggatcgtc gcctctccgt tttgtgggat
    16081 atctataatg aacccgattt agccacgctt cctatcaatg acaacgatcg gctcaaagaa
    16141 ggctggcggc tggcctatca acgtattaaa caacggattc ccggtgcgca gattgtgggg
    16201 cccagtatca gccggtaccg actgctgaag ccttttctcg aatggagtca cgaccacaac
    16261 gtgtttccgg atgttgtggc ataccacgag tatgacgacc cgtcacacgc tcctgcgctc
    16321 gtggaggatt tacggagtta cctcagaggt cgaggtatcg tcagacctat ttctgtgaat
    16381 gagattctgg ggcaggagag ctggactctt gctgggtaca ccgtcggcgt cattgcggca
    16441 tatgagcgcg cgaatatcct gagtgccatg cgatcctgtt ggccggatcc gcaagatatg
    16501 agccgcgatc gagtggaaaa tacttgtgac aatcctacgc tggatggtct gctctatgtc
    16561 gatcggcaat cgaagcggcc gggatggcac atctacaaag cctatgcgga aatggatggg
    16621 gtacgactcg ctacgatgac cgacagtcca aaactccatg cgctggcgtc atttgataaa
    16681 gcttccggta ccctccagtt gttattaggc aagtacgagg actattcaac ccaggacacg
    16741 actgtgatgc tcaaaaatgc cgcccgggtc ttctcaggcg ggcaaggaaa gaatctcttt
    16801 ctctgtgctg agcagattcc ggacacgggg tccggcccgc tcgcctcgac cgtggtgacg
    16861 atggatcgta cgttgccgct tccggataac gacatctcct tcaccttgcc tcagttttac
    16921 cattcggatg cctacagggt gaggatatcg cccacatccg ggtgcaagcc tcgcgattaa
    16981 ccactccacc ggcgtggtgt cagagtattt ccaacggata tcgaccccgg cggcatctct
    17041 caaacgctgc tttccgtcaa agcctcaggg ctaggttcgt ccccctcctt cgagcagccc
    17101 cttccccaac ctggacaatt gtggccgcac ggcatcccgc tgtacgctcc ctccaaccat
    17161 cgataggcgg gcgagcgtaa ttcggcgctg tgccggattg ttgcgtatcg atggacgagt
    17221 ccagtccacg accagcgaag aaaaggtatc cctccttatg caagaccagg ccgcagtgtg
    17281 taccgatacg ccaaccaatc aacaggctgg ccagccgcca acccctcaga atgccgttcg
    17341 atcctggctg cttcgcgcgg tggctctctt catcaaaccg gcacactttt ttgcgacgtt
    17401 cgacgatctc gcacggccgg tggtgctgct tgtggccacg ctgtgtttgg gtgttgcttc
    17461 catggtagac cgaatcgagc agcacattct ccgtgcagaa atggggcagg gagtctccgg
    17521 atggtcggag ctgagtccgt ggctgctcca ttcatggggc acactttgga tcgcgcttct
    17581 cgtgtgtggg gctctgaatg tgcctctgtt ctggtatctg ggcgggtggt ggtaccgcct
    17641 tcgtctcaag tggtctggag ccacggcgtt ggattcactc cggccacgtc tcctgttcgt
    17701 ctattcttcg ctggtgtatg cccttccagt tgttctcgtc atgataggcg aaacgctgct
    17761 gtttcccaat taccgcctgg cgagggatgc ggaggggagt tggacgctca tctttgtgtt
    17821 gctgtcattc tggtcggtgg tcgtgagtta ttgtggtgca accaggacct tcgcccttgc
    17881 acggagaaag gcgttgctct ggtttctcct ccttccctgg actctgtatg ccgtagagct
    17941 gggtctgtgg atgtggctct ttgaag
//
LOCUS       DAOQPD010000082        17752 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1600_length_17752_cov_25.122168, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000082 DAOQPD010000000
VERSION     DAOQPD010000082.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 17752)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 17752)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17752
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1600_length_17752_cov_25.122168"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..199)
                     /locus_tag="PK063_15440"
     CDS             complement(<1..199)
                     /locus_tag="PK063_15440"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98493.1"
                     /translation="MKQEGIKIAPLDEKTVFHRLVVLIAVPSSRRSIYPKSTTMHAPM
                     RDSVTGRFRRRYSCSSCQMLRV"
     gene            complement(327..827)
                     /locus_tag="PK063_15445"
     CDS             complement(327..827)
                     /locus_tag="PK063_15445"
                     /inference="COORDINATES: protein motif:HMM:TIGR00608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HMZ98494.1"
                     /translation="MKTALDQHQLGIYDVPRYTISLIKEAASTFHAKTRCQPSEDVYR
                     YFKDICENQDREHLYALFLDTKHVPIGMNHVAMGTLSTTIVHPREVFKCAILLNAACL
                     VIVHNHPSGDPSPSPEDRALTTRIAEAGQLLGIALLDHVVIGNGRYFSFADHGPLTQQ
                     TLTYTS"
     gene            complement(2006..2449)
                     /locus_tag="PK063_15450"
     CDS             complement(2006..2449)
                     /locus_tag="PK063_15450"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98495.1"
                     /translation="MRVLEAHGDLWDVHAQGSWIAITTNGVIRTNGHGVMGAGLAKQA
                     ADRFPSLPSLLGTHLRRFGNIPTSIPSMRIMTLPTKHHFRTASDLALIQNSLQHIQLI
                     LTRERIDRLYCPHPGCGLGQLSWQQVRAAIVHVVDHRFLFLHSTA"
     gene            complement(2554..3483)
                     /locus_tag="PK063_15455"
     CDS             complement(2554..3483)
                     /locus_tag="PK063_15455"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98496.1"
                     /translation="MADSDFLSYAQLCQFVREQGRLPRLDDPIPAYRYAGWALPMIWE
                     GHRVLPGVPNRWGYHLDILHARRIPDAPIPQIEFLHTPHRDTLTHLQRWVTLAAEHQS
                     SWTGLTNLIAWIAFSLKLNHVPPSLADNTQAALYQAVNLQELVLHPYDYWGDIIAEGI
                     GRGPWANPNGFYPTPMSVCQLIVQMMLPDADSLSPAARNALRVKSIADPAGSGTGRML
                     LLASNVSLSLHGIERDALVRTACLINGALYAPWLAFPLPQEILHGTDAEHGLTNQASL
                     LSVATPIPEEISLIPPINDAVDHEGLQLVFPGW"
     gene            complement(3594..3971)
                     /locus_tag="PK063_15460"
     CDS             complement(3594..3971)
                     /locus_tag="PK063_15460"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ98497.1"
                     /translation="MAIILIVDDYSDIRACLRTMLEEAGHIIVEAGSGQEALHAWNET
                     HPDLVITDHSMPGMSGVELIRALGQRQPEVKGILMSADQDPRPAEPPDQSHAWPFLQK
                     PFGFRALRQAIDSLLLAQPAEPA"
     gene            complement(4243..4479)
                     /locus_tag="PK063_15465"
     CDS             complement(4243..4479)
                     /locus_tag="PK063_15465"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HMZ98498.1"
                     /translation="MSNEDTSHPQLPTSYDAAFKELEDLSARATKGDINIDELSTAIQ
                     RGNQLFAFLSSGIAKIKAEIEDHAQDGITQSKPN"
     gene            complement(4469..5902)
                     /gene="xseA"
                     /locus_tag="PK063_15470"
     CDS             complement(4469..5902)
                     /gene="xseA"
                     /locus_tag="PK063_15470"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR00237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HMZ98499.1"
                     /translation="MTMSLPSTHSTETPQPILSIGMLSQRIRRQLAPMLTKQTYLLQA
                     QWIKPQANKGQKGFFSVTLADTDNPNMAIDAMIWEPAVIRKVLEQGQQFGHDLLSRDS
                     RVEVVVEATLGFWANKNTIYVLIHQLSTIGMLGLRQQQREAALRTLKEEGLLTRNASL
                     PWPRFPLRIGIIGKQGSDAVHDILNVLHSSPYRFETTIFHTAVQGVGAIPGLLKAFHD
                     VAAHTTPLDVIVMSRGGGNEIDLVAFDNLDVARAVATASKPVLTGLGHHLDRSICDEV
                     AAKALSTPTAAGQYLVSHLDRIRECLFTTHATLHAHTRHTLLEWTHALTLTRHALWER
                     ARNTIEAHATASHHAHERFQRALRDRLEASYQQGKTLRYSLTASLTQALSQLSMGYAF
                     TLVRLHTAGLSRVDTLKGAITAFVQALTLSDPQHLLARGYAYVLDNQGRMVTSHRTVI
                     AGAQLHIHVQDGRITATTLHTEPSHEQ"
     gene            complement(6507..6725)
                     /locus_tag="PK063_15475"
     CDS             complement(6507..6725)
                     /locus_tag="PK063_15475"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98500.1"
                     /translation="MKKDYAVSVIFPEVLVKHSRQHIRISASNLRLAANEALKAIMKR
                     EGIKGRRLTRLQLAVIHAGTSTIQDHEA"
     gene            complement(8207..8398)
                     /locus_tag="PK063_15480"
     CDS             complement(8207..8398)
                     /locus_tag="PK063_15480"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98501.1"
                     /translation="MAFIEQHGRKIYQFSDNPPRPRHQYQILSGIPLPDIPRYQETPL
                     EYHARTGYPLDLCRRYLNP"
     gene            complement(9275..9493)
                     /locus_tag="PK063_15485"
     CDS             complement(9275..9493)
                     /locus_tag="PK063_15485"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98502.1"
                     /translation="MGPLATSLRQIISTIIRYLPGGASAPRLAHEEARAQQERVDLAM
                     LQILVQESERPHTDVSLSASPLKDDPHP"
     gene            complement(9534..10112)
                     /locus_tag="PK063_15490"
     CDS             complement(9534..10112)
                     /locus_tag="PK063_15490"
                     /inference="COORDINATES: protein motif:HMM:NF019843.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ98503.1"
                     /translation="MTLGCSLGMTLLGAGVVLAQPVDLPAVARCQMEADSQPNRQTLI
                     RNWIHRAGRTDALAALCLSFSPNPNAGESLAWLRRAADLGLPDAQLLLGADLEVGFKS
                     PPNSQEAMRWYRKAAQADFPFAQYELGAIYSEGRANQRQDLPEAYYWAQLAARHQFRP
                     AKELADTLSPQLSHDERARIDARIKKWKRVVS"
     gene            complement(10317..13508)
                     /gene="dnaE"
                     /locus_tag="PK063_15495"
     CDS             complement(10317..13508)
                     /gene="dnaE"
                     /locus_tag="PK063_15495"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: protein motif:HMM:NF004226.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HMZ98504.1"
                     /translation="MPTPFVHLHTHTTYSLLDGATLLDPLIEHVRWLNQPAVAITDHG
                     NLFGTIPFYTKARSAGIKPIIGCEVYMAKGSLLDKKPPEGPRDFYHLILLAQNSIGYH
                     NLIRLVSHGYTEGFYYKPRIDKSLLRSHSSGLIALSGCLTGEIPTLLQQEQFASASVA
                     AQEFLDIFGPDRFYLELQANGLHQQQRVNQGLIHLHRELGIPLVATNDCHYLKRGDAD
                     AHDLLLCIKTGTTITDTTRLRFGTDQLYVKSSEEMAEAFRELPQAITHTNLIAEQCTL
                     EIPLHRTQLPRYNVPPPHTLDSFLETLAQQGLSARLAHHSGPLDRPTYERRLRTELLT
                     ICSMGFAGYFLIVWDIMKFARSRRIPVGPGRGSAAGSLVAYALGITELDPLAYDLLFE
                     RFLNPDRVSLPDIDMDFCMKRRQEVINYVTEKYGRDHVAQIITFGTLGAKAAIRDVGR
                     VLEIPYDEVDTIAKLIPSQPNMTIAQALAEEPRLSALSASHPSVGTLLSVAESLEGLA
                     RHASTHAAGLVISNTPLLETVPLCRTTSDDIVTQFGMGELEQLGLVKFDFLGLKTLTV
                     IDHTISLINQQSLGSRPLTLDDIPLDDAKTFALLASGRTTGVFQLESNGMRELLREFQ
                     PDRFEDITAIIALYRPGPLDLIPEFIQQKRGQYPLASNIAALEPILSTTYGVIVYQEQ
                     VMAIANTVAGFSLGQADILRRAMGKKKPEEMRALHAQFVEGAVGLGTEREAAEHLFQM
                     ITKFAGYGFNKSHAAAYALLTYRTAYLKAHDPLAYMTALMTSDIGDHERLSLYASECR
                     EMGVRLLPPDINRSETGFTIVDGAMLYGLAAIKHVGEYLATQLIQIRATGGTFASFFD
                     LCDRVDRRTVTKRVLDALIKSGALDTLCDHRAQLSAILDDATPAKPTRSQRNVTHQTL
                     LQLFPEESETRVLPKIPAWSPSIRLDHEREALGCYVSHHPVRVHDHQLKRLQVVPLTQ
                     LPDLPDGKEVRIAGLITRIKRILTKRQEPMAFVHLEDQDRTLEVVVFPSLYRHDSGRL
                     EPGTVIALEGILDQNDQGIKVKATRFLPLDPAA"
     gene            13768..14894
                     /locus_tag="PK063_15500"
     CDS             join(13768..14023,14023..14894)
                     /locus_tag="PK063_15500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611153.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HMZ98505.1"
                     /translation="MKRTRRNHGAAFKAQVAVAAIKGDKTLAELAEQFSVHPTQITEW
                     KQQLLARAADVFGGTTPTSDTPDLKVLHAKIGQLALENDFLGRGAHQGGIVERKTMIN
                     RTHALPVVRQCQILGLSRSTAYYQPTPVSGTELALMRRLDELHLRHPFAGARMLRDLL
                     RQEGQAIGRRHVATLMRRMGLEALYRKPRTSHRHPAHPIYPYRLRDLTISRPNHVWAA
                     DITYIPMAQGFVYLFAVLDWASRRVLAWRLSNTLTTDFCLEAVQDALAHYGTPEIFNT
                     DQGCQFTSQEFTGLLKDHGIQISMDGKGCWRDNVFVERLWKSIKYEEVYLHAYETISA
                     AQQGVARYLTFYNQTRPHQALDGQTPDQVYYDHLTTRRTAA"
     gene            15003..15143
                     /locus_tag="PK063_15505"
                     /pseudo
     CDS             15003..15143
                     /locus_tag="PK063_15505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012736482.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(16009..16563)
                     /locus_tag="PK063_15510"
     CDS             complement(16009..16563)
                     /locus_tag="PK063_15510"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98506.1"
                     /translation="MLTFLEMSYAWSAWIQRWGLSAILWIFTASLTHAAQPLPQELMN
                     QWFAVEVLSGARIPLSIEFVPSPWSLIRLRLAPDERLLVLFNAPVQDCTISGDARLDP
                     DRDRIHIRSHAITCRTARGFETRVFAGTVVSETDGFQGVPLSLAHQSQDQKGYIVPAG
                     VQGTLVVLPHNPPERVDAPPPSRK"
BASE COUNT         3713 a         4495 c         5581 g         3963 t
ORIGIN      
        1 tcacgcgaag catctgacaa gaggaacagg aatagcgccg ccggaatcgt cccgtcacgg
       61 aatcgcgcat aggtgcatgc atggttgtgc tctttggata aatgctgcgt cgagaggaag
      121 gaacggcaat caacaccacc agccgatgga agacagtttt ctcatctaat ggggctatct
      181 tgattccctc ctgtttcatc cgagtttcaa tagattaacc cacgctgtgg gctcagagtc
      241 tgtcgaaaac tagccgctcg gacacctccc gctgttgcgt ttcgaatcaa agctcatggg
      301 acgtcggaag aaccttcgca gttatcttag gacgtgtatg tgagagtctg ttgcgtcagt
      361 ggtccgtggt ccgcgaagga gaaataccta ccgttgccga tcaccacatg atcgaggagt
      421 gcgatgccga ggagctggcc cgcctcggcg atccgagtcg tgagggcccg gtcttcgggg
      481 ctcggtgagg gatcgccact tgggtggttg tgaacgatga ccaggcaagc cgcgttcagg
      541 agaatggcac atttaaagac ttctctaggg tggacgatcg tggtgctgag tgtgcccatt
      601 gccacatgat tcatcccgat gggcacatgt tttgtatcga gaaagagagc ataaagatgt
      661 tcgcgatctt ggttttcgca gatgtctttg aagtatcggt agacgtcttc cgatggctgg
      721 catcgagtct tggcgtggaa cgtcgatgcg gcctctttga taagactgat ggtgtagcgc
      781 ggaacgtcgt agatcccgag ctggtgttga tcgagagcag tcttcacggg cgatcctctc
      841 ctcatggtga gccggtgagt gcgagcgcac gctggttttc gtgacgctac cctgtcaggc
      901 gatgatgtgc ggcgcgttgc ctgcgaagca tatatagccc ttctcgaacg atgtagacgg
      961 ccaagagcac gaggcgccca ccaagcgcga ggatcaggag caggccaatc ccaccacata
     1021 gaagagcaag ggtgacgact agcagtgcgc ggacgttcag gagatcaaaa gtgtgtgttg
     1081 cggtctcttc tatgtgaggt ctctgaaacg aaagctgcct gccgactgga ctgatcttcc
     1141 acgatatcgg cgtgccacct gtattccgct gcatctcaac ggtgtctctg tcgtatggag
     1201 gaggtaacgg cgtacttggg agcggaggcg tcgagcgtcc ggaggagcag ccagcatctg
     1261 ccgcacgctg acagaaatgc ttccaaacgg ccggaatgta cgcggtggac ccgttgtagc
     1321 cggcaacggc tctccaggtg cgaccatgct tctggattga ggtctgaagg atcaaactcg
     1381 aggcgtagag attgacacat ggttctagaa gatcgcgaga ctggatttgg tggtgtctgg
     1441 ccagccagcc caggtgttgt gaactgatct gagcgatccc gatgtcaaca ttgggagcgg
     1501 tctggagaag acgtaggagc atggcgaccg catcctcctg gcgacgtgga gcataactgt
     1561 gtcgtctccc agtttggtcg ctccatccca aggcccaggg gtgacctgcc gactcggttt
     1621 ggacgatcgc atggaagagg tcaggatcga tggcgagggt ttgggcatag tggatgaggc
     1681 attgctgcca cgatgctccc gtgagcggag cttccggttt ggtctgtgcc aatgtttgag
     1741 aaggagatgc gggcaatatg agaaatagcg tcaacgagat agccgcgtaa gcctgacgac
     1801 gcatggcaag tctccctctt gtgaatggat ggtacgcgac catcctccac tctgcgtgcg
     1861 acgcacgcct gaggccgttt ctggtacgaa gacagtgatg ggtcgtgagg tgacgtctag
     1921 ctggcgagaa gagatgcgag ctggggacgt gtctcacatc tgttgaaggc gaatggccga
     1981 cgctcatgga agcatgagca ggaactcaag cagtagaatg caggaagaga aatcgatgat
     2041 cgaccacgtg cacaatcgct gctcggactt gctgccagct tagctgaccg agaccacatc
     2101 ctgggtgcgg acaatacagc cggtcgatgc gttcacgtgt gagaatgagc tggatgtgct
     2161 gcaggctatt ctggataagg gcgaggtcag acgcggtacg aaaatgatgt ttggtgggca
     2221 gggtcatgat ccgcatggag ggaatcgatg tgggaatgtt gccgaaacgg cgtagatggg
     2281 ttcctagcag cgagggcagg ctaggaaacc ggtccgcggc ctgtttggca agccccgctc
     2341 ccatgacgcc atgcccattt gttcttatca ccccgtttgt tgtgatggcg atccaagagc
     2401 cctgagcatg aacatcccag aggtcgccgt gtgcttcgag gactcgcata ctctccctcc
     2461 ccacctaggt gacaaccaac acattggcgc gcagcgcgag ccagtaccgg gtgggtcggt
     2521 cggcaccggt tgcgtgctgt cagcgtatct cgctcaccat ccaggaaaga ccagctgcag
     2581 gccctcgtga tcgacggcat cgttgatggg aggaatgagc gaaatctctt caggtattgg
     2641 cgtggcgact gagaggagcg aggcttggtt tgtgaggcca tgttccgcgt ccgtgccatg
     2701 gagaatttct tgaggcaagg ggaatgcgag ccagggggcg tagagagcgc cgttgatgag
     2761 acatgccgtg cggaccagtg catccctttc gatcccgtgg agcgagaggc tgacgttcga
     2821 tgccagcagg agcatccttc cggttccgga tcctgcggga tctgcaatgg atttgacccg
     2881 caaggcgttc cgtgcggctg gggagaggct gtcggcgtcg gggagcatca tctgtacgat
     2941 gagctgacag acgctcatgg gggtcggata gaacccgttt ggattggccc acggcccacg
     3001 tccgatcccc tccgcgatga tatcgcccca ataatcgtaa gggtggagta ccaattcttg
     3061 gagattgacg gcttggtaga gtgcggcttg cgtgttgtcc gcgagcgacg gggggacgtg
     3121 gttaagtttt aaagagaacg caatccaagc aatgagattg gtgaggcctg tccagctgga
     3181 ctgatgctcg gcggcgagcg tgacccagcg ttgcagatgc gtgagtgtgt ctcgatgagg
     3241 ggtgtggaga aattcgatct gcggaatcgg ggcgtccgga atccgtctcg cgtgaagtat
     3301 gtctaaatga taaccccatc gatttggaac cccaggcagc acgcgatgcc cttcccaaat
     3361 cattggtagg gcccatccgg cgtaacgata ggctgggatc gggtcatcta accgtgggag
     3421 acgtccctgc tcccgcacaa actgacagag ttgtgcatac gacagaaagt ctgagtcggc
     3481 catagcctgg tacatcccat taagcgacgg gttagtgatg cagtggagac cggaagggtg
     3541 gacgaacgca gatgtctggg gtgaagaggc gcgaaagacg cttggcggat gctctaggct
     3601 ggttccgccg gctgagccag cagaagcgaa tcgatggctt gccgtagcgc ccggaagccg
     3661 aagggcttct ggaggaatgg ccacgcgtgg gattggtctg gtggttccgc ggggcgcgga
     3721 tcctgatcgg ctgacatcaa gatgcccttc acttccggtt gccgctggcc taaagcgcga
     3781 atcaactcga cacctgacat cccaggcatt gagtgatcag taattacgag atctgggtgg
     3841 gtttcgttcc aggcatgcag tgcttcttgg ccggagcctg cttcgacgat gatatgtccc
     3901 gcctcttcga gcatcgtccg gagacaggct cggatgtctg aatagtcgtc aacgatcaga
     3961 atgatggcca tgcgaggtct ccatggctga agggtgttgg aacagggcca gcgtggattg
     4021 agtcaacgat tgaatacggg tccagagttc ggcggcccgt acatggcgtg gacggtgccg
     4081 ggcggttctg agtctgatgc ggtctgcagc cgtccactgc ttggctaaga gatccagagt
     4141 ttgatcgatc gtgatcgggt gagtgtgatg gtgtttcgac atgactgagt gagtcctctt
     4201 ctgaatgggg acatggtccc tggaacatcg gatgccaagc ggttaattgg gcttggattg
     4261 ggtgataccg tcctgagcgt ggtcctcgat ctcagctttg atcttcgcga tgccactgct
     4321 gagaaaggca aacagctggt tccctcgttg aatggccgtg ctcaactcat cgatgttgat
     4381 atcgcctttc gtagctctgg cggagaggtc ttccaattcc ttgaatgccg cgtcatagga
     4441 cgtgggcagc tgggggtggg acgtgtcttc attgctcatg cgaaggctcc gtgtgaaggg
     4501 tggtggcggt aatcctgccg tcctgaacgt gaatatgtag ctgcgctccc gcgatgaccg
     4561 tcctatgaga ggtcaccatc cgtccctgat tatcaaggac ataggcatag cctctggcaa
     4621 gaagatgttg tgggtctgag agggtcaagg cctggacgaa cgcggtgatg gcgcctttta
     4681 gggtatcgac gcgcgaaagt ccggcggtat gcaggcgtac cagtgtaaag gcgtatccca
     4741 tggacaactg tgagagcgct tgtgtcaggc tggcggtaag gctgtatcga agggtttttc
     4801 cttgctggta gctggcttcg aggcgatcgc ggagtgcgcg ctggaatcgc tcatgggcgt
     4861 ggtgggacgc tgtcgcgtga gcctcgatcg tgttccgggc gcgttcccag agggcatgcc
     4921 gggtgagcgt gagtgcatga gtccattcca gcaacgtgtg tcgagtatgg gcatgtagcg
     4981 ttgcatgggt cgtgaagaga cattcgcgga tgcggtccaa atggctgacg aggtactgcc
     5041 cggcagcggt tggcgtagac aaagcttttg ccgccacctc gtcacagatc gaccgatcga
     5101 ggtggtggcc cagcccggtc aggacgggtt tgcttgctgt cgcgacggcg cgggcgacgt
     5161 cgaggttatc aaacgcgacc aaatctattt catttccgcc tccacgcgac ataacaatga
     5221 catcgagcgg tgtggtgtgt gcggcgacat cgtggaatgc cttgagaagc cctgggatcg
     5281 ctccgactcc ttggacggca gtgtggaaaa tagtggtttc aaatcggtac ggactgctgt
     5341 gcaggacatt taagatatcg tgaacggcgt cacttccttg cttgccgatg atgccgattc
     5401 gcaatgggaa tcgtggccat ggaaggctgg cattgcgagt aaggaggccc tcctctttga
     5461 gggtgcgaag agctgcttcc cgttgttgct gtcgcagtcc aagcatgccg atcgtgctga
     5521 gctggtgaat gagcacatag atcgtgttct tattggccca gaaccccagc gtggcctcga
     5581 cgacgacctc gactcgagaa tcccgactca gcaggtcgtg gccgaactgt tggccttgtt
     5641 cgagcacctt cctgatgacc gctggttccc agatcatggc gtcaatcgcc atatttggat
     5701 tgtctgtgtc cgccagagtg accgagaaga agcccttttg ccccttattg gcctggggtt
     5761 tgatccattg ggcttggagc aagtacgtct gcttggtcag catcggcgcg agttgtcgac
     5821 gaatgcgttg cgagagcatc ccaatagaga gaattggctg tggcgtttcg gttgaatgag
     5881 tagatgggag agacatcgtc atggttctca gggctgtgtc agtgctcggt tagggcgtcg
     5941 tggtatcagc gaggcggttg ccctgcgcgt gagcgccatc cggttagtaa acatccgtcg
     6001 tcactcatcc atcaggaggc gtctgtcttc ggcacactga catcagtgtc cgtccgtgcc
     6061 caagatcggt cggacgccat ggctctgtgg agttggatgg cccaggggac ccccacagtt
     6121 gcggatataa aggaccgaag cgcgaggtct tgttcaagat atcgaggagc ccgagtccaa
     6181 tcggcccgag cgaatagaac acggccgtcc agtcgatgct catttccagt aggatgatgg
     6241 tcgtggcgtt gagcagaatc agactcctga aggtgtaccc taaccgtttc ggctcgagga
     6301 gccgacaaag ctggttggca aaaaaagctg cgatgatcgt catgccaacg ccaaacgagt
     6361 cattgtccgc tgtggccatg gcttcctgac gacggcagag catgagcatc gtcgcgctgc
     6421 aactgagggt gagtatttgt cagcgtagga cgctacccca ctggggatga agacgaagac
     6481 ccatagcctt catgaggtgt gttcgcttag gcctcgtggt cctgtatcgt gctcgtgccg
     6541 gcgtggatca cggccagttg caagcgagtc agtcgtcgtc ctttgatccc ttcccgtttc
     6601 atgatggctt taagggcctc atttgcagcc agccgtagat tactcgccga gattctgatg
     6661 tgttgccggc tgtgcttgac caacacttca gggaagatga ccgatacggc gtaatccttt
     6721 ttcatagcgc ctcgtgagtc gagggaacgg cttgggtgcg agacttcaac tccgtagggc
     6781 tcgccccttt gagagcaatc agggtgccgg gattgggaag ttgggcattt gctgtacaag
     6841 tccaacagag gtagtgcccg tccggaaacc tgcaatgcgg catgtcgtga gttgcccgcg
     6901 gcctcggcat atagctttga caggggaacc tgggatcccg ctcaccggga actccgacag
     6961 ggttccctcg gaactctgtt ttccaccgtc gaaacgcaaa gagacagagc catctccaga
     7021 acatggcctg aagcgaaatg gattcactgc ggtactccag catctcgttc cggaagtcga
     7081 tcgagaaagt ggttgtgcga ggcatagggg tggggaccta ttccaaggat aacgttcatg
     7141 tagatgtatt actgactgcg aaggactgaa atcgagataa tcggtggaca gactctcaaa
     7201 attgtcgttg cagaacctgc gttgcgtgag tagacggatg tgtgtggctt tgatgggaaa
     7261 cgcgctgcca atcagattcc gctatttcag agcggtggtc ttatactgta acccctcgat
     7321 gtcgacccaa taccgcacaa cctcccgatt atcgcgtcgg cgacgaatcg tggcggatcg
     7381 cgtggggtcg ccaaggaccc accgttgtgc cgtctcatcg cttcgcattt cgtgagtgta
     7441 gtgtcgctcc caatatggtg aatgccgtct gacatgcgtg agaaacaatc tactgcctat
     7501 ggataggacg gcatatacag ccgtccgtcc ggggatcgaa atcgttgagg ggaggctaac
     7561 tgagtttcgt cgcgaatcat gcgtgtcctg gagtcagtcc tgtgcgtgga tggcagctaa
     7621 agggtgaagg tggatactgt gtttggtaat ccgatgatct gcggcttgat cgatgcagtc
     7681 cgtcggccat tgcgtttccg gattgtgatc cgcttttgca ggatcgcctg ttcccaggtg
     7741 tcctctgtcg tatgaacgac cgccctccga gtttgtgtca gcgcactcca gatgaaatga
     7801 cagaagtccc agcgtctcgc ttcgtctggg acctgggcaa tgtgggcgag gagggagcgt
     7861 tcatctctct cgtttttatc ctccgcgatg agccagcctt ctccgcttcc gttaaaccat
     7921 cgcagtgcaa tctgccgatg ctctggacgg atgaaaatat catagcggta ggagtcgcca
     7981 gtccacttcg tctgtttgct aaaactgcag ggtcttcctg gtccgaagcg tgctgagcac
     8041 acgtgtgtcc attcggcggg attaacctgg atcgcaacat accggtttcc gtaaggcgga
     8101 tggaggagat atccagattc ttgaatcctc atcggtggaa tgggaggttg gttcatacgt
     8161 cctcatgtgc agtagtggca ggaatgccct gttgctactt gggttgttag gggttgagat
     8221 agcgtcggca gagatcgagg gggtatccgg tacgcgcgtg gtactccagc ggcgtttctt
     8281 ggtaccgtgg aatgtcggga agtggaatgc ccgagagaat ctggtattgg tggcgcggcc
     8341 gtgggggatt gtcgctgaac tgatagatct ttcttccgtg ctgttcaatg aaagccacgc
     8401 aagtgtctct gctgaaactc tgagggagcc gataccgttc gagaatgctc gcccaaggta
     8461 cgccgtgcgt atagagatcg aaacagagtg tatagagaaa atgcgggtct ccaattggca
     8521 ggagggggac gtacaacgag ccgtctggtt gaggtgtcac ttctcggaca tgggcataga
     8581 caattggcgg ttccggtttt tgtatcgact ctgttgcggg gagagactgg gctttccgga
     8641 tgtgggcgca ctcggctcgt cggtaggtcc aatgtggaca ggtgcattgc cagtcattgg
     8701 cctggcttcg agtgacggta tagcaaagcc ctggcttgga attcgacgcg atggagaagg
     8761 attcggcgta gggcatacag ccttcctgtg cgacttgagc ctgactagag gggagtgaac
     8821 cagactacca ggtcggcagg atctgtggag cggccgtcgt ctgaggcatg agatgggttg
     8881 gtatcgtgat ggggcagcct gacagacgtg tgatctaccg ggatgcagtg aaatcaaaaa
     8941 aggaagcggc ggccggctca gtcggagcgg ggttcatcca ccaacttggg tcatccagtg
     9001 atggtgcata cgagactatg gggtcgatac atcgaccacg gtctttaatt tggtcgagga
     9061 tgtcctcctc actcgcaaga tactcgctat cggtgaaggt ctcacatcga aggtgaggca
     9121 ccggtggggc gatcccagga ggaagcgggg cgcctgggag atacccgaga aggtagagga
     9181 ggacaacggt cgacatggtc ggcatagcgc ctcatcaact cgatggacac cattctatcg
     9241 aagcgtgtga acgggggcaa tcggccctgc gggcttaggg atgggggtcg tctttcaatg
     9301 gagaggctga caaactcacg tcggtgtgag gccgttcact ctcttggacg aggatctgca
     9361 acatggcgag atcgacacgt tcttgttgcg cacgggcttc ctcgtgggcg agacgaggag
     9421 cggatgcgcc tcccggcagg tatcgaatga tggtcgagat aatctgacga aggctagtgg
     9481 ctaggggtcc cataccaaca cagtaaatcc gaatcggttc ggcacaggat aggctacgag
     9541 acgacgcgct tccatttctt gatgcgggca tcgatgcgcg cgcgctcatc atgtgagagc
     9601 tgtggactga gcgtatctgc gagttccttg gccggtcgga attgatgccg ggccgcaagc
     9661 tgcgcccagt agtaggcttc aggcaagtct tgccgttggt tggccctgcc ttccgaataa
     9721 atggcaccga gctcgtattg ggcaaaaggg aaatcggcct gtgcggcctt ccggtaccag
     9781 cgcatggctt cttggctatt gggaggactc ttgaatccta cctcaaggtc tgcaccgaga
     9841 agcagctgtg cgtccgggag tccgagatcc gccgcgcgcc gtagccacgc cagggattcc
     9901 cccgcgttgg gatttggaga aaatgagaga cagagcgctg ctagcgcatc ggtccgccct
     9961 gcccggtgaa tccagttccg gatgagtgtc tgccggttgg gctgcgagtc ggcctccatt
    10021 tggcatcgcg cgaccgcagg caagtcgacg ggctgagcta gtacgactcc cgcaccgagg
    10081 agcgtcatgc cgagactgca cccgagtgtc atgaggccgt ggcgactcca gcgtcgtacg
    10141 ggcgatagaa atgcactgat ctctgacaga ggtaagctgg aagtcagtgt ggccgtcatg
    10201 gtgagagcaa ctcctttttg aacgcaactc attcttgatg aaacccacgc cgaggtgatg
    10261 tcgtcgttgc gtgtgtatta ccggatgggc agtgctctcc ctggtttgtg gggagattag
    10321 gcagcaggat caaggggaag aaatctggtg gctttcactt ttatcccctg gtcattctga
    10381 tcaagaatac cttcgagcgc gatgacggtg ccaggttcca gtcgccctga gtcgtgtcga
    10441 tagagacttg gaaagacaac gacttccagt gtgcgatcct gatcttctag gtggacaaag
    10501 gccatcggtt cctgccgttt ggtcaggatg cgtttgatcc gggtgatcaa tcccgcgatt
    10561 cgcacttctt tgccatccgg gaggtcaggg agctgagtta agggaacaac ttggagacgc
    10621 ttcagttggt ggtcatggac acgtacggga tggtggctga catagcaccc gagagcttct
    10681 cgctcgtggt ccaatcgaat agatggagac caggcaggta ttttgggcag cacgcgagtt
    10741 tctgactcct ccggaaagag ttggagcagg gtttggtgtg tgacgttccg ctgagatcga
    10801 gtgggtttcg ctggcgtcgc atcatctaga attgcggata gttgtgcgcg atggtcgcag
    10861 agcgtgtcga gggcgcccga tttgatcaag gcatcgagta cgcgcttggt gacagtgcgg
    10921 cggtcgacgc ggtcgcaaag atcaaagaag gaagcgaagg tgcctccggt tgcacgaatc
    10981 tggatcaact gtgtggcgag atattctcct acgtgcttga ttgcggccag accatagagc
    11041 atggccccgt ccacgatcgt gaatccggtc tcactccggt tgatgtcggg cgggaggagc
    11101 ctgacgccca tttcccggca ttcactggca tagagagaga gtcgctcatg gtcgccgatg
    11161 tcactggtca tcaacgcagt catgtaggcc agcggatcgt gagccttaag ataggccgtc
    11221 cgataggtga gtagcgcgta tgcagcggca tgggacttgt tgaacccata gccagcgaac
    11281 ttggtgatca tctggaagag gtgttcagct gcctcacgct ccgtgccgag tccgacggcc
    11341 ccttccacaa actgtgcatg cagggcgcgc atctcttctg gtttcttttt gcccatagcc
    11401 cggcgaagaa tgtcggcttg gcccagtgag aatccagcca cggtgttggc gatggccatg
    11461 acttgttctt gatagacgat cacgccatag gtggtgctga gaatcggttc gagggccgcg
    11521 atgtttgagg cgagaggata ttgcccgcgt ttctgctgaa taaactccgg aatcagatcg
    11581 aggggccccg gacgatagag cgcaataatc gctgtgatat cttcgaaccg atcaggctga
    11641 aattcccgaa gcagctccct cattccgttg ctttccagct gaaatacccc tgtggtacgt
    11701 ccgcttgcga ggagggcgaa ggttttggcg tcatcgagcg gaatgtcgtc cagcgtcaac
    11761 ggacgggatc ccagggattg ctgattgatc agtgagatgg tgtgatcgat cacggtgagg
    11821 gtctttaatc cgagaaaatc gaacttcact aggccaagct gttcgagttc ccccattcca
    11881 aattgcgtca caatgtcgtc gctcgtggtg cggcataagg ggactgtctc cagcaggggg
    11941 gtattggaga tgaccagtcc cgccgcatgg gtggaggcat gtctggcgag cccttcaagg
    12001 gattcggcga ccgatagcag ggtgccgacc gaagggtgcg aggcagacaa ggcacttaat
    12061 cgtggttctt cggcgagcgc ctgtgcgatc gtcatgttgg gctgagacgg aatcagcttg
    12121 gcaatcgtgt cgacttcatc gtagggaatt tcgagaacac ggcctacatc gcggattgca
    12181 gctttggcgc ccagggtgcc aaaggtgatg atttgtgcga catggtctcg gccgtatttc
    12241 tccgtgacat agttgatcac ctcctgccgt ctcttcatgc agaaatccat atcgatgtct
    12301 gggagggaaa ctcgatccgg attgagaaac cgttcgaaga ggaggtcgta ggcaagcggg
    12361 tccaactctg taatcccgag cgcgtaggcc accaggctac ctgcggcgga cccgcgtcct
    12421 ggtccaactg ggatgcgccg ggagcgggca aacttcatga tgtcccacac gatcaagaaa
    12481 tagccggcga agcccatgga acagatggtg aggagttcgg tccgcaggcg gcgttcatac
    12541 gttgggcggt cgagaggacc cgagtggtgg gcgaggcgtg ccgacaaccc ttgttgggcg
    12601 agggtttcaa gaaaactgtc gagggtgtgc gggggaggca cgttgtaccg aggaagttgt
    12661 gtccgatgca gaggaatctc gagcgtgcac tgttcagcta tcagattcgt gtgtgtgatg
    12721 gcttgaggta gctctcgaaa ggcttcggcc atctcctcgg aggatttgac gtacagttgg
    12781 tcggttccaa aacggagtct ggttgtatca gtgatcgtag tgccggtctt gatgcagagc
    12841 aataaatcat gggcgtctgc atcgcctcgt ttgagataat gacagtcatt cgtggcgacc
    12901 agcgggatcc ccagctcccg gtgcaagtga atcaggcctt gattgaccct ctgttgctga
    12961 tgaagtccat tagcttggag ttcgagatag aaccgatcag gaccgaagat gtcgagaaat
    13021 tcttgggcgg ccacggacgc ggaagcgaac tgttcctgct ggaggagggt ggggatctca
    13081 ccggtgagac aaccagacag tgcaatcaag ccggaactgt ggctgcgcag caaggacttg
    13141 tctatgcggg gtttgtaata gaagccctcc gtgtacccgt ggctgaccag gcgaatgagg
    13201 ttgtggtatc cgatactgtt ctgggctagc aggatgaggt gatagaaatc acggggtccc
    13261 tctgggggtt ttttgtctaa cagactgccc ttggccatgt agacttcgca cccaatgatc
    13321 ggcttgatgc ctgccgatcg tgccttggtg tagaagggga ttgtaccaaa gagatttcca
    13381 tgatcggtga tcgcgacggc tggttggttg agccatctga cgtgttcaat gaggggatct
    13441 agaagagtgg cgccatcgag caggctataa gtggtgtgcg tgtgcaaatg gacaaaaggt
    13501 gttggcatgg cactccagat cgatgggaag agtcctctag gcggaggatg cgagtaatcg
    13561 cttgtcggga ggtggtggcg cggccggctc tgagtttgaa tggcttgtgt atgtgtggtt
    13621 gtgggattcg gaggaggctc aatactagtt tggcctaaaa gctaacactt aatctgagag
    13681 agggctccgg aaattcggac agtgtgctaa gtggtagcct ggcttcaccc acaccaccgc
    13741 gaggtggcct acgagaggag cgaggcaatg aagagaacga gacggaatca tggagccgcc
    13801 ttcaaggcgc aagtggctgt cgctgccatc aaaggcgaca agacgctggc cgagttggcc
    13861 gagcaattca gtgtccatcc cacgcagatc accgaatgga agcaacaatt gctggcgcgg
    13921 gccgcggacg tatttggcgg caccacaccg acgtcagaca cgccagatct caaggtcctc
    13981 cacgcgaaga tcggccaact ggccctggag aatgattttt tagaaggggc gctcatcaag
    14041 gcgggattgt tgagcgcaaa acgatgatca accgaaccca tgccctgcca gtcgttcggc
    14101 aatgtcagat cctcgggttg tctcgctcga cggcctacta ccagccgacg ccggtgtcag
    14161 ggacggagct ggcgctgatg cgtcggctgg acgaactcca cctgcgtcat ccgtttgctg
    14221 gcgcccgcat gctgcgcgat ctcttgcggc aagagggcca ggccattgga cggcgacatg
    14281 tggcgaccct gatgcgccgc atgggcctgg aggccctgta tcgcaagccg cgcacgagcc
    14341 accggcatcc ggcccacccc atctacccct atcgcctcag ggatctgacg atcagtcgcc
    14401 ccaatcacgt ctgggcggcg gatatcacct acattccgat ggcgcagggc ttcgtctatc
    14461 tgttcgcggt gctcgactgg gccagtcgtc gggtgttggc gtggcggctg tccaacacgc
    14521 tgaccaccga cttctgcctg gaagcagtcc aagacgccct ggcccactat ggcacgccgg
    14581 agatcttcaa taccgatcaa gggtgccaat tcaccagcca ggagttcacc ggattactga
    14641 aagatcacgg catccagatc agcatggacg ggaaaggctg ttggcgggac aacgtgttcg
    14701 tggaacgact gtggaaaagc attaaatacg aggaagtgta tctgcacgcg tacgagacca
    14761 tcagcgccgc ccagcagggg gtagcacgct acctgacgtt ctacaaccag accaggccgc
    14821 accaggcgct tgacggccag acgcctgacc aggtgtatta tgaccatctg acgacacggc
    14881 ggaccgccgc gtaatcagca acccgccagg cgccacttaa ggaaggggtt acactgtcca
    14941 accaaccgga gccacctctc tgacagacag atagagtcct cagcacgaaa gaagcgagga
    15001 ccatgatgac ggaacaaaag atcatcagga cgaaggtggg cgtgttggaa ctggcgaagc
    15061 agctaggcga tgcctcaaag gcctgtcagg tgatgggcta cagtcgagat agcttctacc
    15121 gcctcaaaga tctctacgag acccatgggc tcgctgtgaa aggcagtttc atagctctgt
    15181 ctcactatct tcacagagct ttccgcattg ctcacacgcc tcgcccggca taagccccgc
    15241 aatgcatggg cccgagcacg ttgtgtggga ttctccccgt gccgcagcga gagcatcctg
    15301 tgcgaatctg catgactcgc cctggtcctc tgcccatcgg actaagagtg ctagttgctc
    15361 gtacagtttc ggagctgcag cgatcaggta tgcgtttgct aggactttgt ttccatcgtt
    15421 gaggtgctca gcgatcaccg caatcgttaa atcttcatcc ccgtccgctc gtggcgtgac
    15481 aatgctcacc ggaccattgt agctgagttt gatccgccat agtcctggca tccattgcgt
    15541 taggggtgcg tctgcttctt tcatactgac gtctttctct tcagcgatcg ggcaccgtcg
    15601 cctggtattg gcgggctagc tccttctcct cgcttaggcc acgcattcac gtcatgctac
    15661 acttgccgcg tgatagtgtt cgtacgcgcc cctgcactcg ggatggcgct gctccatctg
    15721 cgagtaccgc acgtgacctg cgcgcttgcc aaacacgcga atgagtgttt cgtgcccctc
    15781 tgatgggtcg cgacggccgc gacgtatgca tcctacacag tcctggcatg cgcgactttc
    15841 agcccatggt ggagatcttc agtgcatccc gctccccgta tggttcgcac ggcgaggggc
    15901 attcagtgtg gaggagaact ccgtttcatc tttaaaatgc ctccaccgag agactgaagg
    15961 caccaagaat gtgcagcgga tgcgggcagc gaaagagagg gacagcgttt acttgcgaga
    16021 tgggggagga gcgtcgactc gctcgggagg gttgtgcggg aggacgacca gggtgccctg
    16081 gactccggct ggtacgatgt accccttctg gtcctggctt tgatgcgcca atgacaacgg
    16141 gaccccttga aacccgtcag tttcagaaac caccgttcca gcgaagactc tagtttcaaa
    16201 tcctctagca gtacggcacg tgatggcatg gcttcggatg tggatccgat ctcggtctgg
    16261 atcgagccgg gcgtcgccac taatcgtgca gtcttgtacg ggagcattaa ataacaccaa
    16321 cagtcgttcg tccggcgcca gccgtagccg gatcagtgac catggagatg gcacgaattc
    16381 aatcgacaac ggaattctgg ctccactcaa gacttcaacc gcaaaccatt gattcatcag
    16441 ttcttggggg agaggctgtg cggcgtgcgt cagactcgcc gtaaaaatcc ataatatagc
    16501 ggaaaggccc cagcgttgga tccaggcgct ccatgcgtac gacatttcca agaaggtaag
    16561 cattcgatgc ggctcgtcgg agcttgacct cctttgatcg aagtattgcc ccttgtatta
    16621 ctgactttct tcagaggtgt cgtgcgttca tggctacgaa gccctaccca tggactcggt
    16681 gtggggtaag cctaatacac gggagatttc tgtcgaagtg atggccagag aacgcgctga
    16741 gccagtgtcc atatcgatat atgttgcgaa acggcgaagg tctttggtga tgacgagtcg
    16801 aagcaggtag tccgccatgt gcgaggcaat gatgctattg atcgtgagcg attgcgggtc
    16861 acctagggca agttccgcac atgaccgctg ttgagtattg acggggcggc gttctcgctt
    16921 gagcaactct gggtgcacaa gcgctggcgc ggggagtgac tggcacacag tgcgtagctg
    16981 aaagctctcg tgtgggttaa agtctgtgac gacgttgcca actaacactt gcccgtgggt
    17041 ggtgaggttc ccgccatcaa tcagccatgc ctgggcatcg tttctggtgt tccatcgcgc
    17101 gagcgcgtga tgaaggctgc gcctggctct tgctgtgtca acgcaaccga gaagaatggt
    17161 cagggtgtcg tactcaggat gggcctcttt ccccgagaaa tgccgcggac acgcgcgaat
    17221 gggaatcccc caagcggtgg agagtcgaaa tgctaaggcc tctgctttat tgtgtccgat
    17281 ttctgcctga caaaagtttt gacggcggag gttcttctct tcaattgtgt ccccatcata
    17341 gaaagtgacc atcaccgtat caaacagacg aaaacactcg cgtgcgaggc gtgcgacgtg
    17401 gataccgaga aacgctccga tgcccccaca tccgatttgg atgacatgga ggcgtgggca
    17461 ctgcttagga agcactttca cggcgtgcac atgactaaga tctaggtgtg tcctggtgct
    17521 tttttctgtg ctgcgcttcc ctgtagcgac aacacgtcgc ggcgacatct cgtccctcat
    17581 ggtgtgtacg tgtcctgaag tgtgggaggg agctctgcaa cgaactccgc tgggattggt
    17641 atgaaatggc catacagccc gacacgaaac gtaatggacg ggcgagtggt caaccatcca
    17701 cacacaccgt atattcgaaa ccctgtttcg tcttcattgt ccacggcgga aa
//
LOCUS       DAOQPD010000083        17731 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1604_length_17731_cov_22.569812, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000083 DAOQPD010000000
VERSION     DAOQPD010000083.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 17731)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 17731)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17731
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1604_length_17731_cov_22.569812"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(327..671)
                     /locus_tag="PK063_15515"
     CDS             complement(327..671)
                     /locus_tag="PK063_15515"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98507.1"
                     /translation="MTDDYARRKVQVIKEFLESQFPTPYVVEAIVPRRDPLADTKYKV
                     ILNNVVERTLLVCPAVVMDSFPTPDHLKESLVARNIIDKVKASTDSRICHDDLGTDDQ
                     NYQKPIRSVRGL"
     gene            1120..1461
                     /locus_tag="PK063_15520"
     CDS             1120..1461
                     /locus_tag="PK063_15520"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98508.1"
                     /translation="MKVCAGEYDSRSGLESLVCTTCKHRGLRSREGIIPLFRGGHEFK
                     FSYGPSTRTVTVVLSSAAVNLWGTHGVNEEQLAKLAAEWTLLCGNTKKPVQLGIPSEE
                     FADFYLYFCRK"
     gene            complement(1560..2126)
                     /locus_tag="PK063_15525"
     CDS             complement(1560..2126)
                     /locus_tag="PK063_15525"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98509.1"
                     /translation="MSKPIPLECPRCLLANPDAAQYCECGYDFTPHFEGFPLKSSPGA
                     APRKRLFSEEMGRGSFVLGILLIWLALSVGELYRIRIELPRRPKMELGFSSLMVGMTD
                     LAAALVVGAIGWACVWIVLAAQSKRDGSLCPKRTTFVVTLIAAGLLFVTRTIDPSVLV
                     QHVMQVLFVLAIAIASYYAGCRNWLGKW"
     gene            2197..2589
                     /locus_tag="PK063_15530"
     CDS             2197..2589
                     /locus_tag="PK063_15530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF423 domain-containing protein"
                     /protein_id="HMZ98510.1"
                     /translation="MQASTPSFRFACFGALFAAAAVAAGAFGAHALKSILDPAMLTVY
                     ETAARYQMYHALGLFVVAWLSRETHSPLAIKAGWLFCAGILLFSGSLYLVALAGIKWM
                     GALTPLGGVSFISGWACVAWTAWRAGRP"
     gene            complement(2586..3554)
                     /locus_tag="PK063_15535"
     CDS             complement(2586..3554)
                     /locus_tag="PK063_15535"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98511.1"
                     /translation="MPNPRGCLFVVACCVVTLLTSSIAVRAEEASPPPKPTLANRLPA
                     FQDVAKANAAQLSALPAQGDALSLFKTIIGPQLGLGDAAMTIGAKGLTPTMSQELLIS
                     DLTRAANELVRGLAAWQLVQATRDLDTSGTAESRQEMHKRIEAQTAWLSDGTTLAPAL
                     ERVQTLTAAAPTEETAPLLGGAVAQIEAWALDTVHREWFRIYNWKDQVRQQRGLVRLC
                     GTWQWSIHNHQNHREEKTAVIFAPPGSVSGTSPAEIIVLGDSVYLRWETRAGVQEDSL
                     LFSGEGQRLEGTFVNSAGGWGSITGKRTATCFNDGGKPTSPRRQHH"
     gene            complement(3654..4445)
                     /locus_tag="PK063_15540"
     CDS             complement(3654..4445)
                     /locus_tag="PK063_15540"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013866.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HMZ98512.1"
                     /translation="MTTQTAPFSLDQIGTGTARFPSGMAIPTATDAMVDPYIRTRVSK
                     DVHVECIQFWPQDKVTYPGIVLLHDWWGMNSQITALGARLACEGYGVIIPKLYGRLGG
                     MVTANAEVAEALAAKCNEQLLLQDINTCCEYLNTTERTKRNIHGVVGFGLGATLAIRF
                     ACQRKRLRAAVAYYGKVTAPDQLTNMMSPLLYHQAEHDTWATQADADLLRSAAAQGKR
                     IEIKTYPGTTHAFCDETRPAEHNAEATAQAWDATVAFLKTCFQGT"
     gene            4617..5585
                     /locus_tag="PK063_15545"
     CDS             4617..5585
                     /locus_tag="PK063_15545"
                     /inference="COORDINATES: protein motif:HMM:NF014893.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HMZ98513.1"
                     /translation="MPLGIGLIGLGHHGSRYAKHLLHDLPEARLVAVCRRRAERGNGL
                     PDAATVPCYSDYRELIADSRVEAVVVVTPPTLNRAMCTSVAQAQKALLVEKPLATTAE
                     DARAIMQAARASGQVMMTAQTLRFDAAVSALRARQAEAGALQYLSLASRMEPHADSED
                     WGFGGRGCVLEIGIHLLDLVRVLTQDEVLTVCCEMDRVAPAGAERRMLGRLTTGSGLV
                     CVLDVSRVTSGRIGRVELIGSEGQLSADWCGQRVTRVSARHGAGEWPTAAEPTVLSTL
                     RAFVRAVRDGLPPPITIEDGKRAVEIAEACYLSASQGGRAVTVEYR"
     gene            complement(5587..5823)
                     /locus_tag="PK063_15550"
     CDS             complement(5587..5823)
                     /locus_tag="PK063_15550"
                     /inference="COORDINATES: protein motif:HMM:NF013224.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC ligand binding domain-containing
                     protein"
                     /protein_id="HMZ98514.1"
                     /translation="MATKAYILIKVKAGKGKSVLTALKGIAGVEQIHACFGQPDIFVF
                     INVADERALSDVVITRIHAIEGVEETDTHIVAET"
     gene            complement(5894..6532)
                     /locus_tag="PK063_15555"
     CDS             complement(5894..6532)
                     /locus_tag="PK063_15555"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98515.1"
                     /translation="MPATPAARPGEVPDFFMRVSLAITLLSLAPLAPDIGWSQQATGE
                     TTPVMRTVAQPSRTASVYIGSVMAMLATFEDAGILPPEGTPQANRIIKAVIQFQSAFL
                     KSDHPAIRQFFTEAHRAKLGPRADEVETSFRQSGWSADTFDAVITAGQLETAWNTDGL
                     SDGFREFNIGKQDFDILAELYQQSSRAFSTQGKSFQEVYAQRRREMPGAKSE"
     gene            6758..8287
                     /locus_tag="PK063_15560"
     CDS             6758..8287
                     /locus_tag="PK063_15560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HMZ98516.1"
                     /translation="MLAKVLSAAIVGIDAHLVDVEVDISAGLPQFSIVGLPDATVRES
                     RDRVRAALKNSGFQFPIKKVTVNLAPANIKKEGAGLDLAIALGILVAEDVIAAEAVNN
                     TVFVGELSLDGRLKPIPGALSIGVVCRHRHRIFVTAENAEEAALADGAEVLPIHTLPQ
                     AVECLRGVQPIAALLLTGDGGAASLLPEDEDFADVKGQAHAKRALEVAAAGGHNLLMM
                     GPPGSGKTMLARRLPGILPVLAQEEALETSRIHSVVGQLSRDQPLMRRRPFRAPHHSI
                     SEAGLIGGGTMPRPGEVSLAHNGVLFLDEAGEFGRATLDALRQPLEDGHVTVTRASGS
                     LKFPARFMLVAAMNPCPCGYYGDRTRDCVCSVAQVRRYRGRLSGPLLDRLDLQIEVPA
                     VPIRALGDDAPVTDSSATIRTRVMAARARQAQRYRRDGIYTNAQLKPRHLKQYCALDS
                     QGRELLEQAMARLGFSARAHGRILRVARTIADLAESDSIGPAHLAEAIQYRSFDRRVE
                     L"
     gene            8284..8514
                     /locus_tag="PK063_15565"
     CDS             8284..8514
                     /locus_tag="PK063_15565"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98517.1"
                     /translation="MRETPVIHTARVFAWWFIVGATMALAVILLQGGIREAMQAQGSV
                     WELKLVEFLTTILGGGLLGGCIALILDRIKKS"
     gene            8557..8982
                     /locus_tag="PK063_15570"
     CDS             8557..8982
                     /locus_tag="PK063_15570"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98518.1"
                     /translation="MDIEVGSNLYRNSNGIIDIEGVPQFEVAIKEPARALLVNFALFD
                     EVGRMMAKVVDSNLTFNERRAYQLAKSPTSVSLKHEESGTVVFALELREGNRVVFSKG
                     SFHTIKGHRLDVSQTEWRIDKKHFSGKETDTKGGAVFLG"
     gene            complement(9025..11619)
                     /gene="clpB"
                     /locus_tag="PK063_15575"
     CDS             complement(9025..11619)
                     /gene="clpB"
                     /locus_tag="PK063_15575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HMZ98519.1"
                     /translation="MDMNRMTVKLQEALQSASALAMRRGHQGIDVEHLLLALLEQERG
                     IASSLFEQAGVSPAAVRQAADQALAKVPQVQGPGAAPGQIHLTPRLGAVLTKAEDQMK
                     ELRDEFISVEHVVLAMVEEGGVFRRLNLTRDRLLTALQQVRGNQRVTSQDPEGTYQAL
                     EKYGRDLTKLAGQGKLDPVIGRDDEIRRTIQILSRRTKNNPVLIGEPGVGKTAIVEGL
                     AQRIVKGDVPEGLKQKRVVVLDMGALVAGAKFRGEFEERLKAVLKEVQSAQGQVLLFI
                     DELHTVVGAGAAEGAMDAANLLKPMLARGEMHLIGATTLDEYRKHIEKDAALERRFQT
                     VLVDQPTVEDTISILRGLKERYEVHHGVRIKDAALVAAAKLSNRYIGDRFLPDKAIDL
                     VDESAARLRTEIDSLPAELDEVSRKVLQLEIEREALKKETDAGSKARLQSIEKELNEK
                     NRDLQALKTRWESEKNSVSKLRKIRQQIEEVKQNIERSERAYDLNKVAELRYGELPRL
                     ERELELEQQSLGKKQNETRLLKEEVDEEDIAAVVSRWTGIPVTRLVEGEMEKLLKLDE
                     LLHKRVVGQEQAVTAVADAVVRARSGIKDPNRPIGSFLFLGPTGVGKTELARALSVTL
                     FDDESNLIRIDMSEYMEKHTVARLIGAPPGYVGYEEGGQLTEAVRRHPFSVILFDEIE
                     KAHHDVFNILLQVLDDGRLTDSQGRTVDFKNTVLIMTSNIGSQHILEAQQAGASYETM
                     KNQVTGELRAHFRPEFLNRVDEIVVFHALGNEHLAKIVEIQLERLRARLMERRITLTV
                     TPEALQSLGRRGYDPVYGARPLKRLIQQEIETPMARQLIKGELRDGDTAVVDLKDGQI
                     CIVPTVAP"
     gene            11858..12676
                     /locus_tag="PK063_15580"
     CDS             11858..12676
                     /locus_tag="PK063_15580"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98520.1"
                     /translation="MLTIFNSTLQLYRDALHATWRSLVRGWFVILAVIVFTLLMMLAH
                     QIARPLGMLGGFLLGAVNALLIGATLSLIEQSIKGMRTITMHDVLESMGHYFWDVISV
                     GFVLWIPTMLLDTSLRANPDSQFLVMACLLLVFILLNPAPEVIYLTRHDSPLDVLKRS
                     YDFVLDNWIEWFLPMALVLAPLGLSLFFKLSSQLGRGAGLDFIQLVLVPFTILSAWLT
                     DLGISANLTGMMALLLTPPLMVGMLLFRGHLFSALSSTSRRQRAYQSQFHDSAR"
     gene            12743..14293
                     /locus_tag="PK063_15585"
     CDS             12743..14293
                     /locus_tag="PK063_15585"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HMZ98521.1"
                     /translation="MSEVVYGLTCTAASAGPRIHHQGADLVVRLSIFWRLVLTYLVII
                     AVMTGVNVYALLQIRTLAGLNTEVGSHHHPEIDSAKRLLTSIYEQVQGEKKYVAVPAA
                     TFLEHFDSESKEFQQVLQGLLAHDVSEPETRLLKEIEGLQQAHLSLFQSQLAESSGHP
                     EASAGYDARREAVVGKMAAALQQYIGLHERRLAVGVNESHASSVHAEAVTRNLVLVAL
                     LFGLGMAAVASYNILRPLRRLQATIQEMGQGNFKASWDGQAPRELRELGETVKWMGTK
                     LQQLDDIKSEFLAHVSHELRTPMASIQEGTHLLLDEIPGPLTQDQRTTLRIMSDSSRR
                     LMYLISTILDLSKMESGMMEYRFVPTDLRRVADISINKIRLLADAKHVQLVIEAPVER
                     HWVRADSTRIEQVLDNLLSNALKYSPEGAVVRLQMTPRRDEGLLFVDVADAGPGIPAE
                     ELPHIFERFYQGRTKSRQVSVGSGLGLALAKKVVEAHGGRIWVESEVGKGTTVRFILS
                     LMKPGMLA"
     gene            14413..15063
                     /locus_tag="PK063_15590"
     CDS             14413..15063
                     /locus_tag="PK063_15590"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98522.1"
                     /translation="MLQAILRKDSSLVTKCASKNTCDHVFFTRALTSLYESRESAIHN
                     FEKVIAVAPKSQLAVSSRLWLQLLQAGEVPSDQSWLRSVWNGPAIAQTQGVLSQTIER
                     TVRDLLDRELTIQQLRALQDSEAQSLEAMQRELQDQERKAELFNSRRESHRMSVEPAT
                     LQSLQRQVSDRDKKIEELTSQLEALKRIDQEMRGKTRPIKPPSSVLPSQQSEPSKP"
     gene            15072..16487
                     /locus_tag="PK063_15595"
     CDS             15072..16487
                     /locus_tag="PK063_15595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ98523.1"
                     /translation="MEQERILVVDDDEGLLHLLRMRLSALGFSVTPCTTGRDALVAAR
                     QETFDIAITDLRLRAEDGLVLTEELLQVQPGLPVIILTAHGSIPNAVEAMQRGAFGYL
                     TKPFDDKELKATIDKALIQLRMTREIQRLKSLVKELYGLENVIARSPAMQRLFQQVAQ
                     IADSDATILLTGETGTGKEVLARVLHANSRRAKGPFVALNCAAISEHLFESELFGHIR
                     GAFTNAMAAKRGLFQSANGGTLFLDEIAEMSLPMQVKLLRAVQEREVREVGADYTTKV
                     DVRIITATNKDLAECVKQGTFRHDLYYRISVVPLNIPALRERRDDIPLLAQHFLKQSA
                     RRSNKDVRGFTPAAMHRLIGYPWPGNVRELENAVEKAVVMSRQDMVLPELLPSAGAST
                     DIGLKPLTEAKEEFERSYLRNVLQMTGGNISRAAQFAGRYRADFYKMLKKYGLHPSML
                     KERHDLDLAEIEESAEELKDV"
     gene            complement(16872..17237)
                     /locus_tag="PK063_15600"
     CDS             complement(16872..17237)
                     /locus_tag="PK063_15600"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ98524.1"
                     /translation="MQNRYSQRVPMDCSVMFAGDNCVGEGRILDISLPGCLLESPKQM
                     TAGEYLQLRLFLPDHQAPLHVPLAAVRWVEGSKLGIEFIRTSEDEQRRLEQFVRRVPA
                     AAHPSIRRNGIVLLGATEQ"
BASE COUNT         3577 a         4882 c         5215 g         4057 t
ORIGIN      
        1 taaaatcctg tgtcatacca atggcgtgcg ggttcaagtc ccgcctcccg caccaaaaga
       61 ccggtcagcg gtgttgtctc tcctcgactc gtcctctctg aactctgctc tccagcctga
      121 ttgaccagtt ctcacactac acgcccttca ctttttcgag cgcatcagta gattctcggt
      181 gattcggctg atcggaagat atgcgcggga cgaacgatgg atcgtgatgc agggggtgtc
      241 actgcgacgc gagacgacgt tccaccatca cagccgtgta atgctggacg ggtctgtcga
      301 taaacgggaa gcggaacagc ggtgcgctag aggccgcgca ccgatcgaat aggtttttga
      361 taattttggt cgtcggtacc tagatcgtcg tggcagatcc gggagtctgt cgacgccttg
      421 accttgtcaa tgatgttgcg ggccacgagt gattccttca gatggtccgg cgtggggaag
      481 ctgtccatca ccacggcagg acagaccaga agggtgcgct ccaccacatt gttgaggatc
      541 actttgtatt tcgtatcggc gagtggatct cttctcggca caatggcttc cacgacatag
      601 ggcgttggaa attgcgactc gagaaactcc ttgatgactt gtaccttcct gcgcgcgtaa
      661 tcgtctgtca cggtcgatgg tccttccgaa ttccgcccct gtcggtttgc cgacggcagg
      721 ggaagcagcg gttgtggttt cagatctctt gtggcacagt gccgtcccgt agagtgctga
      781 tattaagaga aaaaccgact gaaaaccaga ggctggtccc ggccggtcgc aaatcgctgc
      841 gatcttctca cgacttcaca gcgaatgacc gggcggagcc agggtctgtt gtggcgtctg
      901 atatacttgc catagttaac catggcatcg tgtccatgct gagctccggt gggaattttg
      961 tagatggttc accgcatcgc tgaggtcact gtgcaggaaa acgacggttc tggagcggca
     1021 ggcgatccgg cggcaccatc cacaccagtt tcatccctcg cacagatctc gaaagactca
     1081 gatggggccc gttgcccggt tcagaagtgt gacggccgca tgaaggtgtg cgccggcgag
     1141 tacgatagcc gcagcgggtt ggaatctctg gtctgcacga catgtaagca ccggggattg
     1201 cgttcgcgcg agggcatcat cccattgttt cggggagggc acgaattcaa attcagttac
     1261 gggccttcca cgcgcacggt caccgtggta ttgagttccg cagcggtgaa tttgtggggc
     1321 acacacgggg tgaatgagga acaattggcg aagcttgcgg cagaatggac gcttctatgc
     1381 ggtaatacga agaaaccggt gcaattagga attccgtctg aagaattcgc cgacttctat
     1441 ctctacttct gcagaaagta acgccagttt agcatccagc gtagtcacct ccaccgcagc
     1501 tcattctcct acagtttttt cgaatagcct gaggcgggtg ctgcacgtcg gttcatctat
     1561 caccatttcc ccagccaatt tctgcatccc gcataatacg acgcaatcgc aatagccagg
     1621 acgaagagga cctgcatgac gtgttggacc aacacgctgg ggtcaatggt ccgtgtcaca
     1681 aaaagcaggc cggcggcgat gagggtcacg acgaaggtgg ttcgcttggg gcagaggctg
     1741 ccgtcgcgtt tgctttgcgc ggcaaggacg atccagacgc aggcccagcc gatcgccccc
     1801 acgacgagag ccgcggccag atccgtcatg ccgaccatca aactgctgaa gcccaattcc
     1861 attttcgggc ggcgaggcaa ctcgatacgg atgcggtaga gttcgccgac cgacagcgcc
     1921 agccagatta gcagaatgcc gagcacaaaa ctcccgcggc ccatttcttc cgagaacaag
     1981 cgtttccgcg gcgcagctcc cggggaggat ttcaggggaa agccttcaaa gtgcggggta
     2041 aagtcgtacc cgcattcgca atactgcgcc gcatcggggt ttgccaggag gcagcgggga
     2101 cattcaagcg gaatgggttt gctcatttgg gatcggcttc atggtaaaat cgcgcgccct
     2161 gcctccggcc aatgatggag gcttcacgag gtctgtatgc aggcatcaac tccatcgttc
     2221 cgattcgcat gtttcggggc cctgtttgcg gcggcggccg tagcagccgg cgcgttcggc
     2281 gcccacgcgc tgaaatcgat tttggatccg gccatgctga ctgtatatga aacggcggcg
     2341 cgctaccaaa tgtaccatgc tctcggcctc tttgtcgtag cctggctgag tcgcgagacg
     2401 catagtccac tggcgatcaa ggctggttgg ttgttctgcg ccgggatcct cctgttcagc
     2461 ggaagtttgt atcttgtggc gctggcagga atcaaatgga tgggcgcact gacgcccttg
     2521 ggcggggtgt cgtttatcag cggatgggct tgtgtcgcct ggaccgcctg gcgagcgggc
     2581 cgcccttagt gatgttgacg acgcggtgac gtcggtttgc cgccatcgtt gaagcaggtg
     2641 gcagtgcgtt tgccggtgat tgatccccat cccccagccg aattgacgaa ggtgccttcc
     2701 aaccgttgtc cctctcccga aaagagcaga ctgtcttcct gcacaccggc cctggtttcc
     2761 catcgcagat agacgctatc gccgaggacg atgatttccg ctggactggt gcccgacacg
     2821 gatcccggtg gcgcgaagat gaccgccgtc ttttcttcgc gatgattttg atgattgtga
     2881 atggaccatt gccacgtccc gcacaaccgg acgaggccgc gctgttgtct cacctggtct
     2941 ttccaattgt agatcctgaa ccattcgcgg tgcacggtgt cgagggccca cgcttcgatc
     3001 tgggcaacgg ctccgccgag caggggggcc gtttcttccg tcggcgcggc tgctgttagc
     3061 gtctgaacac gctccagcgc tggagccagc gttgttccgt cgctcaacca ggccgtctgg
     3121 gcctcgattc gcttgtgcat ctcctgacgc gattctgctg tgccggatgt atcgaggtct
     3181 cgggtcgctt ggaccaattg ccaggcagcg agtccccgga ccagctcatt ggcggctcgc
     3241 gtcagatcac tgatgagcag ttcttgactc atggtcgggg tcaatccttt ggccccgata
     3301 gtcatcgcgg catcaccgag tcccaattgc ggaccaatga tcgtcttgaa gagggaaagc
     3361 gcatctccct gcgcgggaag ggccgacaac tgcgccgcat tggccttcgc cacatcctgg
     3421 aaggccggca ggcggttggc cagagtcggc ttgggtggag gagatgcctc ttcggcacgg
     3481 accgcgatcg atgaagtcaa cagggtgacg acgcagcagg cgacgacgaa gaggcaacca
     3541 cgaggattcg gcatgcggct atgttctttc tatgcgagaa ggaggagtac cggcatgggg
     3601 cgaccagagc acatcggcca gcgccgtcac cacctgggtc accctcgata cggttaggtt
     3661 ccctggaaac aggttttgag aaatgccacg gtggcgtccc aggcctgcgc agtggcttca
     3721 gcattgtgct ccgctggtct ggtttcgtcg cagaaggcgt gcgtggtgcc cggataggtc
     3781 ttgatctcga tgcgtttccc ctgggccgca gcagaccgga gcagatcggc gtcggcttgt
     3841 gtcgcccacg tatcgtgttc cgcctgatga tacagcaggg gactcatcat gttggtgagt
     3901 tgatccggcg ccgtgacctt gccgtaatag gccaccgcgg cccgcaaccg tttgcgctgg
     3961 caggcaaaac ggatggccaa cgtggcgccc aggccgaatc cgaccacgcc gtggatgttc
     4021 cgcttcgtgc gttcggtggt attgagatat tcgcagcagg tgttgatgtc ctggagcagg
     4081 agttgttcgt tgcacttggc cgccaacgct tccgcgactt cggcattggc cgtcaccatg
     4141 ccgccgagcc ggccatagag tttcgggatg atcacaccgt atccctcaca agccaaccgt
     4201 gcgccaaggg ccgtaatctg agagttcatg ccccaccagt catgcaggag cacaatcccg
     4261 ggatacgtga ccttgtcctg cggccagaac tgaatgcatt ccacatggac gtctttgctg
     4321 acgcgcgtgc ggatgtaggg atccaccatc gcatcggtcg cagtgggaat cgccattcca
     4381 ctcggaaagc gagccgtgcc ggttccaatc tgatccaggg aaaatggtgc ggtctgcgta
     4441 gtcatgggtg atcgggtcct ttctcgattg gcgtctgcgt ccagcgggta gacgcctggt
     4501 actataggga gcggatttgc acattgtcaa tcgacggaat ggtagcgggt gaggagtctt
     4561 gacccgtcag agtgcggccg gtacagtgcg cgccaacgat gcctcacgaa tctcgcatgc
     4621 cgctcggaat cggcttgatc gggcttggcc atcatggcag ccgttacgcc aaacatctct
     4681 tgcacgacct tcccgaggcc cgtctagtcg cggtgtgccg gcgtcgggcc gagaggggaa
     4741 acgggttgcc cgatgcggcg accgtgccct gctattctga ctatcgcgaa ctgattgccg
     4801 attcccgggt cgaagcggtg gtagtggtga cgccgcctac actcaatcgg gcgatgtgta
     4861 cgtctgttgc gcaggcgcag aaggcgctat tagtggagaa gccgctggcg acgacggcag
     4921 aagatgcgcg tgccatcatg caggcggctc gggcgagcgg gcaggtaatg atgacggcac
     4981 agactctgcg gttcgatgcc gcggtgagcg cgctgcgtgc gcggcaggcg gaggccggtg
     5041 cgctgcagta tctcagcctg gccagccgga tggaaccgca tgcggacagt gaagactggg
     5101 gattcggcgg gcgaggctgt gtcctggaga tcggaatcca tctgctggac ctggtgcgtg
     5161 tgttgacgca agacgaggtt ctcacggtgt gctgtgagat ggatcgcgtg gcgcctgccg
     5221 gtgccgagcg gcggatgctg gggcgtttga cgaccggaag cggattggtc tgcgtgctgg
     5281 atgtgtcgcg ggtcacatcg gggcggatcg ggcgggtgga attgatcggg agtgaagggc
     5341 agttatcggc ggactggtgc gggcaacgtg taacacgggt ctccgcgcga cacggggcag
     5401 gagaatggcc gaccgcggcg gaaccaaccg tactcagcac tctacgcgct tttgtgcgag
     5461 ctgtccgcga cggcttgccg ccccccatca ccattgaaga cggcaagcgc gccgttgaaa
     5521 ttgcagaggc ctgttacctc tcagccagcc aaggtggccg ggccgtcacg gtcgaatacc
     5581 ggtgacctac gtctccgcga cgatgtgcgt atcggtttct tccacgcctt cgatggcatg
     5641 aatccgcgta atcaccacgt cggacagcgc ccgctcatcg gccacattga taaagacgaa
     5701 aatgtcaggt tggccgaaac aggcatggat ctgttcgact ccggcaatgc ccttcagcgc
     5761 cgtgagaaca gacttccctt taccggcttt gaccttaata agaatgtacg ctttcgttgc
     5821 catgatgcct cctcaagctg caattcgtca catagtgcgg atgatgttgg ctgcgctcgt
     5881 tgctatgaaa tagttattcc gatttggccc cgggcatttc ccggcgacgc tgggcgtaga
     5941 cttcctggaa gcttttgcct tgagtagaaa atgcgcgact gctctgttgg tacagttccg
     6001 cgagaatatc gaaatcctgt tttccaatat tgaactcccg gaacccgtca ctgagaccat
     6061 cggtgttcca ggccgtttca agttgcccgg cggttatcac cgcgtcgaag gtatccgccg
     6121 accaaccgct ttggcggaat gaggtttcca cctcgtcggc ccgtggaccc agcttggcgc
     6181 gatgagcttc cgtaaaaaac tgacggatgg ctggatgatc gctcttgaga aaggcggatt
     6241 ggaattggat cacggctttg atgatccgat tggcctgcgg ggtgccttca ggcggcagaa
     6301 tcccggcgtc ttcaaacgtg gccagcatgg ccatcaccga accgatgtag accgatgccg
     6361 tccgtgacgg ttgggcaacc gttcgcatca ccggtgtcgt ttcacccgtc gcctgctgac
     6421 tccaaccaat atcaggagca agcggcgcga gagagaggag ggtgatggcc agagagaccc
     6481 tcatgaagaa atccggcacc tctcccggcc gtgctgctgg agttgcaggc atgacactgc
     6541 tcgtcttggc gcgatcacgg caatcgaaga gagacggcat ggcggcatta tacagaagcg
     6601 ccgctacgcg cgctaccgcg ggaaaccacc gcctccacga gctcgccgcg acattgaatt
     6661 cagcggaggc aactgcctat aattcagcca ctggagccac tttgcgacct gttacccatc
     6721 aatttgttga ccgactgatg acgttccggg ggaatctgtg cttgccaagg tcttgagtgc
     6781 agcgattgtg ggcatcgacg cacatctggt ggatgtggaa gtcgatatct ccgccggatt
     6841 gcctcagttc tccatcgtcg gtcttcccga tgcgacggta cgtgagagtc gcgatcgggt
     6901 tcgtgctgcc ctgaagaata gcggctttca atttcccatc aaaaaagtca cagtcaattt
     6961 ggcgccggcg aatattaaga aagaaggcgc cgggcttgat ctggccatcg ccttgggcat
     7021 tttggtggcc gaagacgtca tcgctgcgga ggccgtcaac aacacggtgt tcgtcgggga
     7081 actctcgctg gatgggcgtc tcaaaccgat tccaggcgcc ctctcgatcg gcgtcgtctg
     7141 ccgacatcgt catcgaattt ttgtcaccgc cgaaaatgct gaggaagcgg ccctggctga
     7201 cggcgcagaa gtacttccta ttcacacgct gccacaagcc gtggaatgtt tgcgtggcgt
     7261 gcaacccatc gccgcgttgt tattgacggg cgatggagga gccgcatccc ttcttccgga
     7321 ggacgaagac tttgccgatg tgaaagggca ggcgcatgcc aaacgcgcat tggaagtggc
     7381 agccgccgga gggcacaatc tcctgatgat ggggcctccc ggatccggga aaaccatgtt
     7441 ggcgcgccgc cttcccggaa tcctgcccgt gttggcgcag gaagaagcct tggagacaag
     7501 tcgcatccac agtgtggtgg gacaactttc acgagatcag ccgttgatgc gtcgccgtcc
     7561 gtttcgcgcc ccgcaccaca gtatttcaga ggcggggctc atcggcggtg gaaccatgcc
     7621 gcggcccggc gaagtctccc tcgcgcacaa tggggtctta tttctggacg aagccggcga
     7681 gtttggtcgt gccacgctgg acgcgttgcg acagcctctg gaagacggac atgtcaccgt
     7741 cacgcgcgcg agcggctcct taaaatttcc tgcccgcttt atgctggtgg ccgcgatgaa
     7801 tccctgtccc tgcggatatt atggcgatcg gaccagggat tgcgtctgca gtgtcgcgca
     7861 ggtgcggcgg tatcggggac gattatcggg accgctcctg gaccgcctgg atctgcagat
     7921 cgaggtcccg gctgtgccga ttcgtgccct cggcgatgac gcgccggtga ccgattcctc
     7981 cgcgactatc cgcaccaggg tgatggcggc acgcgctcgt caggcccaac gctaccgtcg
     8041 cgacggcatt tacacgaatg cgcaattgaa accgcgccat ctgaagcagt attgtgctct
     8101 ggatagccag gggcgcgagc tgcttgagca ggccatggcg cgattagggt tttcggcgcg
     8161 cgcgcatgga cgtattctcc gtgtcgcccg gactattgct gacttggccg agtctgatag
     8221 tatcgggccg gcccatcttg ccgaggctat tcaatatcga agtttcgacc gtcgagtgga
     8281 gttgtgagag aaacccccgt cattcatacc gcgcgtgtct tcgcctggtg gttcatcgtc
     8341 ggcgcgacga tggccttggc ggtcatcctc ctgcaagggg gcatcaggga ggcgatgcaa
     8401 gctcaagggt cggtctggga gctcaaactc gttgaatttc tcacgaccat tttgggtggt
     8461 ggcttattgg gcggatgtat tgcgttgatt ttggaccgta tcaagaaatc gtgatgaggc
     8521 atctcggaat gccgggcagc ataaggagtg gtggccatgg atattgaagt cgggtcgaat
     8581 ctgtatcgaa actccaacgg gatcatcgat atcgagggcg tgccgcaatt cgaagtcgcg
     8641 atcaaggaac cggcgcgggc gctgctcgtc aatttcgccc tgttcgatga agtgggacgg
     8701 atgatggcga aggtggtgga cagcaatctg accttcaacg agcgccgtgc ctaccagctc
     8761 gccaagagtc cgacgagtgt ctcgctcaaa cacgaagaat cagggacggt cgtctttgcc
     8821 ttggaactgc gtgaggggaa tcgcgtcgta ttcagcaagg ggtcgtttca tacgatcaag
     8881 ggccatcgtc tcgacgtgtc ccagacggaa tggcggatcg acaagaagca cttcagcggc
     8941 aaggagacgg acaccaaggg aggggcggtc tttttaggat gaccgccctc cgggcatgca
     9001 tcgtcgccct gggtgaatca tgaactatgg ggcgaccgtc ggcacgatac agatctgccc
     9061 gtccttcaaa tccaccacgg ccgtatctcc gtcccgcaat tctcccttga tcaactgtct
     9121 ggccatcggc gtttcaattt cctgctgaat aagccgcttg agcggccgcg cgccatacac
     9181 cggatcgtac ccgcgtcggc caaggctctg tagcgcttcc ggcgtcaccg tcagcgtgat
     9241 gcgccgttcc atcaaacgcg ctcgcaaccg ttccaattga atctccacga tcttcgccaa
     9301 gtgttcgttg cccagggcat ggaagacgac gatctcgtcg acccggttca gaaattccgg
     9361 cctgaagtga gcccgcaatt ccccggtcac ttgatttttc atcgtctcat aggaggcacc
     9421 ggcttgttgc gcttccagga tgtgctgact cccgatattc gaggtcatga tcaacaccgt
     9481 gtttttgaaa tccacggttc gcccctgcga atcggtgagc cggccatcgt cgagcacctg
     9541 cagcagaata ttgaagacat cgtgatgcgc tttttcgatc tcatcgaaga ggatcacgga
     9601 gaacgggtgc cggcgcaccg cttcagtcag ttgcccgcct tcctcatagc ccacatagcc
     9661 gggaggcgcg ccgatcaacc tggcaaccgt gtgcttctcc atatattccg acatgtcgat
     9721 ccggatcagg ttcgattcgt catcgaatag ggtgacagag agggcgcgtg ccaattccgt
     9781 cttgcccacc ccggtcggtc cgagaaacag gaaggaaccg atgggccggt tggggtcttt
     9841 gatgccggag cgggctcgca cgaccgcatc ggccacggct gtgacggcct gttcctgtcc
     9901 cacgacacgc ttgtggagca gttcgtccag cttgagaagt ttttccattt ctccctcgac
     9961 gagacgagtc actggaatcc cggtccaacg actgacgacg gcggcgatat cttcttcgtc
    10021 cacctcttcc ttcagcagac gggtttcgtt ttgctttttg ccaagcgatt gctgctcgag
    10081 ttcaagttcc cgctccagcc tgggcaattc gccgtaccgc agttccgcca ctttgttcaa
    10141 atcgtaggcg cgttcggagc gttcgatgtt ctgtttcacc tcttctatct gctggcgaat
    10201 cttccgcagc ttgctcaccg aatttttttc ggattcccat cgagtcttaa gggcctgcag
    10261 gtcgcgattc ttttcgttca gttctttttc aatcgattgg agacgcgcct tgctgcctgc
    10321 atcggtttct tttttgaggg cttcccgctc gatctccagt tgcaagactt tccgggagac
    10381 ttcatcaagt tccgcgggca aactgtcgat ttctgtacgg agccgcgcgg cggattcgtc
    10441 gacgagatcg atcgccttgt ccggcaaaaa ccgatcgccg atgtaccggt ttgacagctt
    10501 ggctgctgcg acgagggcgg catctttgat tcgcacgcca tgatgcactt cgtagcgttc
    10561 tttgagcccg cgcaaaatgg agatggtatc ctcgaccgtt ggctgatcca cgagcacagt
    10621 ttggaaccgt cgctccaggg cggcgtcttt ctcaatgtgt ttgcgatatt catccagcgt
    10681 ggtcgcaccg atgaggtgca tttcgcctct ggccagcatc ggcttgagga ggttcgccgc
    10741 atccatcgcc ccttcggctg cacctgcacc gaccacggtg tggagttcgt cgatgaagag
    10801 gagcacctgc ccctgcgccg actggacttc cttgaggacg gccttcaagc gctcttcgaa
    10861 ttctccacgg aatttcgccc cggcgacgag cgcgcccata tcaagcacga cgacacgctt
    10921 ctgtttgagc ccttcgggca catcgccttt gacgatgcgt tgcgccaagc cttcgacgat
    10981 ggctgtttta ccgacacccg gctcaccgat caggacggga ttgttcttgg ttcgtcgcga
    11041 cagaatttga atggtacgtc ggatttcgtc atcacggccg atgaccggat caagcttgcc
    11101 ctggcccgcg agtttggtga gatctcgccc atatttctct aacgcctggt aggtgccttc
    11161 cgggtcctgg cttgtcaccc gttgattgcc acggacctgc tgcaacgccg tgaggagacg
    11221 gtctcgtgtc agattgaggc ggcggaatac gccgccttcc tcgaccatgg ccagcacaac
    11281 gtgttcaacg ctgatgaact cgtcacgcaa ttccttcatc tggtcttcgg ctttggtcag
    11341 cactgcaccg agccgcggtg tgagatggat ttgtccggga gcagcaccag gcccttgaac
    11401 ttgaggcact ttcgctagtg cctgatccgc cgcctggcgc acggcggccg gcgagacacc
    11461 agcctgttcg aacagagagc tcgcaatccc tcgctcttgc tccagaagcg ccagcaagag
    11521 gtgctcgaca tcgataccct gatggcctcg gcgcatggca agggctgatg cgctttgcag
    11581 ggcctcttgt agcttgacgg tcatccggtt catatccatg tggctgactc ctgggtgggt
    11641 gtgtctatct actgagagaa cataatcata tcgctgggca agtcaatagc agccgatacc
    11701 cgctatttct tgcggtgctc cctggcgact gcgtgaaatc ttgccgggtg tgacttgacc
    11761 tctcagggga atccatctta ttgtccgccc gacgtgggga gctcgctttc cgctaagagc
    11821 cgcttctctc tgttcgagaa cctgcattga ctgatccatg ttgaccatat tcaattcgac
    11881 gctccaactc tatcgagacg cgcttcacgc aacctggcgc tccctggttc gcggatggtt
    11941 cgtgattctc gccgtcatcg tgttcacgct gctgatgatg ttggcccatc aaattgctcg
    12001 tcccctgggt atgctcgggg gatttctgct gggtgccgtg aatgcgctgt tgatcggtgc
    12061 gacgctcagc ctgatcgagc agtccatcaa gggcatgcga actatcacca tgcatgacgt
    12121 actggaaagt atggggcatt atttttggga cgtcatcagc gtcgggtttg tgctctggat
    12181 tcccaccatg ctcctggaca cgagtctgcg cgcgaacccc gacagtcaat ttctggtaat
    12241 ggcttgttta ttactggtct tcattttgct gaatcccgct ccggaggtga tctatctcac
    12301 caggcatgat tctccactgg atgtcttgaa gcgcagttat gatttcgtgt tggataattg
    12361 gatcgaatgg ttcctgccga tggccctggt tttggcgcca ctcggattgt ccctcttctt
    12421 taaactgtcg agtcagttgg ggcggggagc ggggttagat ttcattcagt tggtcttagt
    12481 gccctttacc attctcagcg cctggcttac cgacctcggg atttccgcca acctcaccgg
    12541 aatgatggcg ctgctgctga ctccaccgct catggtgggc atgctcctgt ttcgtggcca
    12601 tcttttctcg gcgctctctt ccacgtctcg tcgacaacgc gcgtatcaat cgcagtttca
    12661 cgactcagct cgctaggagg tctttccagc cagaccagga cggcgtcctg tttctgcata
    12721 atatggataa cttgttgagg ggatgagtga agtggtgtat ggcttaacct gcactgctgc
    12781 ttctgcaggg cctcgcatcc atcaccaggg agcggacctg gtcgtgcgcc tctcgatttt
    12841 ctggcggtta gttctgacgt atctggtcat tatcgcggtg atgaccggcg tcaatgtcta
    12901 tgcgttgttg cagattcgga cactggctgg cctcaatacg gaagtcgggt cccaccacca
    12961 tccggagatt gattcggcga agcgcttgct gacgtcgatc tatgaacagg ttcagggcga
    13021 gaagaaatat gtggctgtgc ctgccgccac atttcttgag catttcgata gtgagagcaa
    13081 agagtttcaa caagtcttac aagggttgct cgctcacgat gtctcagagc ccgagacgag
    13141 gctgctgaag gagatcgagg ggcttcagca agcgcatttg tcactatttc aatcgcaatt
    13201 ggctgagtcg agcggccatc cggaggcgag tgccggttac gacgcgcggc gcgaagcggt
    13261 ggttgggaaa atggccgcag cgcttcagca atacatcggc cttcacgagc ggcgccttgc
    13321 cgtgggcgtc aacgaatcgc acgccagctc ggtgcatgcc gaagccgtca cgcgcaattt
    13381 agtgctggtg gccctgctct tcggtctcgg catggccgca gtggccagtt acaacattct
    13441 tcgtccgttg cgtcgactgc aggcgaccat tcaggagatg gggcagggga atttcaaggc
    13501 ctcatgggat gggcaggccc ctcgcgaatt gcgggaattg ggtgaaacgg tcaagtggat
    13561 gggcaccaag ttgcaacaac tggatgatat caaaagcgaa tttctcgctc atgtctcgca
    13621 tgaattgcgt accccaatgg cttcgattca ggagggcacc catctcctct tggacgaaat
    13681 tcccggtcca ttgacccagg atcagcgaac aacgctgcgc atcatgtccg acagtagccg
    13741 gcggctgatg tatctcatct cgaccatcct ggatctatcc aaaatggaat ccggcatgat
    13801 ggagtatcgg tttgtgccga cggatctccg gcgggtcgca gatatttcaa tcaataaaat
    13861 ccgattgttg gcagatgcaa aacatgtaca gctggtaatt gaggctccgg tggaacggca
    13921 ctgggtcagg gcagacagta cgcggatcga acaagtactg gacaatctgc tctcgaatgc
    13981 gttgaagtac agccccgagg gtgcggttgt caggttgcag atgactcccc ggcgcgatga
    14041 aggcctgctc ttcgtcgatg tggcagacgc gggaccgggt ataccggcgg aggaattgcc
    14101 acatattttc gagcggtttt atcagggacg cacgaagagt cggcaggttt cggttgggag
    14161 cggcctcggg ttagccctgg cgaaaaaagt cgtagaggct cacggcggaa ggatttgggt
    14221 tgaaagtgaa gtgggaaaag ggacgaccgt gcgattcatt ttatcgttaa tgaaaccggg
    14281 gatgttggcc tagtgcaatg gtgtcgcccc atagggatgg ttctgtgggt aggacttgtg
    14341 tccgcctgtg gcaccctccc ttcgccccca gctcagacgc catacttctc aaacgatggg
    14401 ggagatggca aaatgttgca agccatttta cgtaaagatt cctcgttagt cacgaaatgc
    14461 gctagtaaaa atacctgtga tcatgtattc ttcacccgcg cattgacgtc tctgtacgaa
    14521 agtcgagagt cggccatcca taacttcgag aaagtcattg ccgtcgcccc caagagccag
    14581 ttggctgtgt ccagccgact ctggttacaa ttgctacagg ccggcgaagt gccttccgat
    14641 cagtcttggc tgcgttccgt ctggaatggc cctgcgattg ctcagacgca gggggtcctc
    14701 tctcaaacaa ttgaacgcac ggtgcgggat cttctcgacc gcgaacttac catccaacaa
    14761 ttacgtgcct tacaggacag cgaagctcaa tcccttgagg ccatgcagcg cgagcttcaa
    14821 gatcaggagc gcaaagcgga gctgttcaat tccaggcgcg agtcccatcg catgtcggtt
    14881 gaacccgcga cgcttcagag cttgcaacgg caagtcagcg accgcgacaa gaaaatcgaa
    14941 gaactcacga gccagctcga agcactcaag cgcatcgatc aggaaatgag aggcaaaacc
    15001 cgtccgatca agcctccctc gagtgtcctc ccatcgcaac aatcggagcc gtccaaaccg
    15061 taaggaccgt catggaacaa gaacgaattc tcgttgtgga tgatgatgaa ggtctgttgc
    15121 atttgttgcg gatgcgatta tctgcgcttg gattttcggt gaccccctgc acgacaggcc
    15181 gcgatgcgct cgttgctgcg cgacaggaaa cgttcgatat cgcaatcact gatttgcgtt
    15241 tgcgcgcaga ggatgggttg gttctcacgg aagaactact ccaggttcag cccggacttc
    15301 ccgtcatcat tctgaccgcg cacgggagta tccccaacgc cgtagaagcg atgcagcggg
    15361 gggcctttgg gtatctgacc aagccttttg atgacaagga attgaaagca acgatcgata
    15421 aggccctgat tcagttgcgg atgacgcggg agatccagcg gctgaagtcc ctggtcaagg
    15481 agctttatgg ccttgaaaat gtcatcgcaa gaagtcccgc catgcagcga ttgtttcaac
    15541 aggtcgctca aatcgccgat tcagatgcaa ccattctgtt gaccggcgag actgggacag
    15601 ggaaagaagt cctggcaaga gtcctccatg cgaatagccg tcgagccaaa ggcccgtttg
    15661 tcgcattaaa ctgcgccgcg atcagcgaac atctttttga aagcgaactg ttcgggcata
    15721 tccgtggagc gtttacgaat gccatggcgg cgaagcgtgg tctttttcaa agcgcaaatg
    15781 gagggacgct tttcctcgac gaaattgcgg aaatgtctct gcccatgcag gtgaaactgt
    15841 tgcgtgctgt gcaggagcgg gaagtgcgtg aggtcggtgc ggattacacg acaaaagtgg
    15901 atgtgcgcat cattacggct acgaacaagg atttggcgga atgtgtgaag caggggacgt
    15961 tccgacacga cttatattac cgaatttccg ttgttccact gaatattcct gccttgcggg
    16021 aacgaaggga cgacattcct ctcttggccc aacatttttt gaagcagagt gcgaggcgtt
    16081 ctaacaagga tgttcgtgga tttacaccag cggccatgca tcggctcatt ggatatccat
    16141 ggcctgggaa cgtcagggag cttgaaaatg ccgtggaaaa agccgtggtc atgtcacggc
    16201 aggacatggt attgccggaa ctacttccct cggctggtgc gtcgaccgat attgggttga
    16261 agccgctgac cgaagcaaag gaagaatttg aacgttcgta tttgcgcaat gtgttacaga
    16321 tgacgggcgg aaatatctcg cgagcggccc agtttgccgg ccgatatcgt gctgactttt
    16381 ataagatgtt aaagaagtat gggctgcatc cttcaatgtt gaaggagcgc catgacctgg
    16441 atctcgctga gattgaggag tctgctgagg aactcaaaga cgtttagcgt tcaagtgggg
    16501 ggagcgtgca gaggtgattt cctattaagc gttctaatcg tcttgccgtt gcgtgacgga
    16561 tctttctaat ctgaatcccg aaatctttcc cgctcaccca ctgaactgac gcctcttcta
    16621 tttctaacgg cgaattttga ttgggtaaat ccattcgtaa ggtaagtttc atacctatgc
    16681 tgacttgatg atcgccttgc agccgccatc cgccactcga aatatccctg attatcccct
    16741 tcccgagaaa atcgtctgat aagtagtagc caacattgca ctgcgtgacc ctctggtagg
    16801 tgcgcagcct aaaatgcttt gacatgcaga gctcctatga agatcaggtc atgcactcgt
    16861 tcgagtagca ctcactgctc tgttgctccg agtaggacga tgccgttcct gcggattgat
    16921 ggatgggcag cagcaggaac tctccggacg aattgctcaa gacggcgctg ttcatcttca
    16981 gatgttcgaa taaattcgat gccaagctta gaaccttcta cccatctgac tgcagccagc
    17041 ggtacatgca gcggagcttg gtgatcaggc aggaacaatc ttagttgcaa gtactctccc
    17101 gcagtcattt gtttcggact ttcaaggaga cagcctggaa gagaaatatc taaaatgcgg
    17161 ccttccccca cacaattatc tccggcaaac atgaccgaac agtccatagg cactcgctga
    17221 ctgtatcgat tctgcatggt gcctcctcct cgtatgcctc gggacctata ctgtcgcttt
    17281 caatgcgact gtaatctaag aaccagcgta cgcctagtcc tcagaattgg taacactata
    17341 gtggggacgc tgcggaccct tggcgacagg aatgcctgag ggctaaaaac tgcagaattt
    17401 acggggttca gggaattctt gccaggttgg atctttatca gtaagcggga caaacaccgt
    17461 tcgacgctgc cagtcgaagc cttcacctga aagcctttgt aggagcaatg ctaccccaca
    17521 gcattgactc agctttcaga cagaagaatc tctttctacg tggcatgtca gcgtgggtta
    17581 gatgtattca actggtggtc ggacgaccag aaaaatagtt gccattggca ggagatggat
    17641 cgcctatgca gcaaatatgg tagcaggact gtagtaactg gctcctactt tgattccctc
    17701 ccttcaaccc tctgatagtt ctaggtattt g
//
LOCUS       DAOQPD010000084        17565 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1625_length_17565_cov_18.600514, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000084 DAOQPD010000000
VERSION     DAOQPD010000084.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 17565)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 17565)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17565
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1625_length_17565_cov_18.600514"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..717
                     /locus_tag="PK063_15605"
     CDS             <1..717
                     /locus_tag="PK063_15605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helical backbone metal receptor"
                     /protein_id="HMZ98525.1"
                     /translation="GVTDFCNFPAAAAAKPKVGYSNPNLESLIALRPELIVAPLEFHR
                     ANVLAKLEELKIPVLLLEATSLEQVFAHIHTLGRIFDRSTAAHAMTAEMRQQMAEISR
                     RTEGLARTRVLYVINSQPLITVGPGSYIHQMIGLAGGTNIAAAAATAYPRLTMETVLK
                     EDPEILIFPRGSVETVPRSEQEAWRRWTTLTAVQQNRLREVSADALNRPGPRVMQGLE
                     ALARVIHPEAFDSEPMTIKP"
     gene            714..1874
                     /locus_tag="PK063_15610"
     CDS             714..1874
                     /locus_tag="PK063_15610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HMZ98526.1"
                     /translation="MMPSAGHPTSPPPALTSPSLSPNLMQSGPSFTATDRPFQGAILT
                     RSRWCAVMGALLLLSVILAMLCLQLGTQYIGMGHILTLVWSAVVGTSNEPDALRTTGV
                     ILLQVRLPRVLLGFLVGSCLAAVGVSLQALLRNPLADPYVLGVSSGAALGVAIAVLFG
                     IGTTVLALSLLPVCGFAGSLVALLVIYRMAASYERLPIHSVLLAGVILNAIFSALIMF
                     ITSIMEPNRSFGMMAWLMGSLTAPAYPVLIALSVYLLVGLVLLGKHVRVLDILALGEE
                     PARSLGINTERTKRVIFLLSALMTGAVVSFSGMIGFIGMIIPHAVRLVVGADHRLLLP
                     ASTLVGGMFLMVADTMARTLFVPSEVPVGVITALAGGPFFVYLLVWRKDRLA"
     gene            1871..2767
                     /locus_tag="PK063_15615"
     CDS             1871..2767
                     /locus_tag="PK063_15615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ98527.1"
                     /translation="MSRHLQGKARIDTGAGIGTDAPLAYDVCGAYFCYGRLSTLDVRW
                     VLQNVTVQVQSGEILGIVGPNGSGKTSLLKLLAKLAAPQRGDITLFGQSLAGLSQDDT
                     ARAVACVPQENPQLFPFTVAETVLMGRFPHRHRSRWSLGFGWEDQDDCRAAAQAMETM
                     DITHLASRLVTDLSGGERQRTMIARALAQMPRVLLLDEPTAFLDLQHQLDICSVVRRL
                     REERGLTVVIVSHDLNLASQYCDRIAMLKDGSVAAIGTPSEVMSVETLREVYGCTVLI
                     DAHPDSGLPRITLPGPAVPVHR"
     regulatory      2833..3089
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            3118..5100
                     /locus_tag="PK063_15620"
     CDS             3118..5100
                     /locus_tag="PK063_15620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HMZ98528.1"
                     /translation="MLKRVREWSVCCLLLLIVSTPPVWPAVAGAEEPEEPEPVVQAEE
                     VVISATKTPVPVTQVTSAVEVITAQDMKKQNIRHVADALRLAQGLAVFSSGGPGTEVN
                     ARIRGGGSSQTLVLIDGAIVNSGTLGSYDFSNLTTDNIERVEILRGAQSMLWGSDAMG
                     GVINIVTKRGEGPLTATGFMEYGSFATLREGGTVSGKQGLVDYSLSLSRWDTSGFSAV
                     NYRRGATERDSFRNWQGSGRIGVDLPRDGRLDFTMRWMNSDTQLDNVSATFPADVYGS
                     KMRSQQYVFSGSYEQPITGWWSQKLTLARSQEASLFLPGTVQRSLVDGFISTPFGSPN
                     ETRVLSNRLEWQHNFQVTRLLLLSAGYQFREQQGENDTGLINRVLSSHAGFAQAQFNL
                     WDRVFATAGVRHDSYNVFGNATTYRLTGGYYQKETDTKLRVGYSTGFRAPSMNELYFP
                     NFGNPNLGPEKNQSMDAGIDQYFFSKQLKLSGGFFWNHYRNLIVTTFDPGFCAPFSTF
                     GFCPQQLGEASTKGWEAGLTYTYSSDRPFLKGVVVQAQYTNTITRDLDTQTRLPRWPT
                     DQWSASVSYQPIDPLWITVIGRYVGSRFNTTGDRQAMPAFDVWSLAVTYDVTKQMQAY
                     LRAENLFNEKYEEIASAGTPIRSIFGGLRVTFGGKS"
     gene            5125..6510
                     /locus_tag="PK063_15625"
     CDS             5125..6510
                     /locus_tag="PK063_15625"
                     /inference="COORDINATES: protein motif:HMM:TIGR00379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042242 - cobyrinic acid a,c-diamide
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HMZ98529.1"
                     /translation="MPRPRLVIAGTHSGVGKTTVTLALMAALKARGLVVQPFKAGPDF
                     IDPGHHQLVTGRPSRNLDGWMLNEAVNRSIFSQASADADLSIIEGMMGLFDGSSPIHE
                     QGSTAELAKQLHAPVLLVIDGSAMARSAAAMAAGYARFDPGLSVQGVLFNRVRSDGHY
                     RLLQEAVEAETGLAVVGYLRPDASVTIPDRHLGLRTAIEAGSCDLYDRLAQSAAETID
                     LARVEAIARSAEGWFEEDPVSPPAAGPKETVRVGVAYDGGFCFYYQDNLELLAAAGAE
                     IVQFSPLHDAALPDVDLLYFGGGYPELYGEALAANVSMRAAVKAFSDRGGVIYAECGG
                     LMYLTQAIRDGDGHRYEMVGVFPAEAVMRRSGMTLGYRIVETMRPSLLGPAGTSVRGH
                     EFHYSLLEPKGELAYACVLADAAGKPVGQDGVMVRNTLALYSHQHFRSRPEVVVNLLQ
                     SVRQEKAARQA"
     gene            6523..7122
                     /gene="cobO"
                     /locus_tag="PK063_15630"
     CDS             6523..7122
                     /gene="cobO"
                     /locus_tag="PK063_15630"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008817 - corrinoid adenosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HMZ98530.1"
                     /translation="MTDRDEHTAKMQRLKGSVDRRIEAAQEEKGLLMVYTGAGKGKTT
                     AALGMAIRCLGHGMKVAIVQFIKGAIDTAEERILRSFGDRVMFLRMGEGYTWETQDRE
                     RDTRFAQEAWNKACEFMTDPSYAMVILDEFNIALHHHYVELAEVLPRLQARPLMQHVV
                     ITGRGAPAELIDAADLVTEMKQVKHPFRQGIKAQAGVEF"
     gene            7131..7334
                     /locus_tag="PK063_15635"
     CDS             7131..7334
                     /locus_tag="PK063_15635"
                     /inference="COORDINATES: protein motif:HMM:NF025733.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich CWC family protein"
                     /protein_id="HMZ98531.1"
                     /translation="MSKTCEHCRQPFECVGYQCWCGKIGITEAQMDWIAARYQDCLCP
                     ACLQQVADGKLGPGVPPQADQAR"
     gene            7399..7995
                     /locus_tag="PK063_15640"
     CDS             7399..7995
                     /locus_tag="PK063_15640"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008817 - corrinoid adenosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HMZ98532.1"
                     /translation="MRITKVYTRTGDAGQTRLAGGQQVWKDCVRVEAYGTVDELNASV
                     GLVRAMNAEGGSASPASAQLETDLRWIQNKLFDVGSLLATAPGQSFPNMPKVTEADVT
                     RLEQMIDRCQEDLAPLKEFILPGGGKVSATLHQARTICRRAERDCIRLSREEDVSAEL
                     NKYLNRLSDALFVMARWVAKTQGEPEFLWQRESDAPIK"
     gene            7979..8536
                     /gene="cobU"
                     /locus_tag="PK063_15645"
     CDS             7979..8536
                     /gene="cobU"
                     /locus_tag="PK063_15645"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: protein motif:HMM:NF004469.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0043752 - adenosylcobinamide kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HMZ98533.1"
                     /translation="MPRSSKSTTRPGRAGSRLILVLGGASSGKSQAALERAGSQAPKA
                     FVATGQGLDKEMQARIARHRATRSAEWVTAEVPRDLAGWFRSDGSGYRTIVVDCLTLW
                     LSNVCGRRLAGADMSARVDELVHAIRQSPARVVLVSNELGFGLVPTSRSARAFRDVAG
                     RVNQQIAASADEVYFVISGQSLRLK"
     gene            8546..9601
                     /gene="cobT"
                     /locus_tag="PK063_15650"
     CDS             8546..9601
                     /gene="cobT"
                     /locus_tag="PK063_15650"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008939 -
                     nicotinate-nucleotide-dimethylbenzimidazole
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HMZ98534.1"
                     /translation="MMTLDEAMGLIQPVNGDSAANAQRRLDRLTKPLGSLGRLEELAV
                     HYARITGDVKPNVPRGVVFTFAADHGVAMEGVSAYPSEVTPQMVLNFLRGGAGVNVLA
                     RHTGVEVRVVDIGVAYDFGVVPGLIQKKIMRGTNNLLREAAMTRAQATEALQVGIDLA
                     TEAAQEGVGLIGTGEMGIGNTTPSAGITAVMTGRPVAEVTDRGTGIDEAGHARKVSVI
                     EQALNRHRPDKADALDVLAKVGGLEIAGLAGLMLGAAAARVPVVLDGFIAGAAALMAV
                     ALQPLCRDYLIASHRSVERGHQATLECLALKPLLDLDLRLGEGTGACLGMGLVQASIK
                     ILTEMATFDEAGVTERD"
     gene            9594..10367
                     /gene="cobS"
                     /locus_tag="PK063_15655"
     CDS             9594..10367
                     /gene="cobS"
                     /locus_tag="PK063_15655"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: protein motif:HMM:NF014685.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008818 - cobalamin 5'-phosphate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HMZ98535.1"
                     /translation="MTEIAAMTRPFVFAWHFLTAIPISRTHHAPTAQELASSMAWYST
                     VGLAIGGLVALADVGLRSWMAAEVGNALLIVLLVLLTRGLHQDGLADTVDGLAGGRTV
                     EDRLRIMRDPRVGAFGATALSLSLLLRYAGLLALPAPLRLPVLLCMPALGRWAMVSLA
                     WASPSARRDGGLAASFLTHLSWQQVLLSSLVLAVALTMALGGTVAVATMGMGVLLLVL
                     IRQRCLTLLGGVTGDVLGATNEVVEMLFLLLIPALVVAA"
     gene            10364..11320
                     /gene="cbiB"
                     /locus_tag="PK063_15660"
     CDS             10364..11320
                     /gene="cbiB"
                     /locus_tag="PK063_15660"
                     /inference="COORDINATES: protein motif:HMM:TIGR00380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016880 - acid-ammonia (or amide) ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-phosphate synthase CbiB"
                     /protein_id="HMZ98536.1"
                     /translation="MTGVELAVAAALDVAAGDPRWLPHPVKGMGAVIAWVDDRVRRLC
                     RSEQALQIAGGCLALGLPIAVYAAATWVIAQATAIAPLLGQVVGVGLAYTTLAGRDLF
                     DHVQAVLRELAAGNLAGARQAVAMIVGRDSATLTESGVARATVETIAESTSDGIIAPL
                     VYLSLGGAPLALAYKAVNTLDSMIGHLDARYEHFGWASARLDDVLNWVPARLAGGFIA
                     LAAGLSTGQWHRIHESWYMLHRDGDKHASPNSGQPEAAMAGALAVQLGGTNYYDGVAH
                     EAPSIGDGTADITPQHIRQASRIMIVTYGLGLFFALLSLWVS"
     gene            11317..12426
                     /gene="cobD"
                     /locus_tag="PK063_15665"
     CDS             11317..12426
                     /gene="cobD"
                     /locus_tag="PK063_15665"
                     /EC_number="4.1.1.81"
                     /inference="COORDINATES: protein motif:HMM:TIGR01140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0048472 - threonine-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine-phosphate decarboxylase CobD"
                     /protein_id="HMZ98537.1"
                     /translation="MNRQAHGGDVYAAARELKRNVRHLLDFSASINPLGPSPAAWRAI
                     GRGSELLSHYPDPACRDLRQALATFWDRSPEEFLIGNGSTELIHLLPEALQIRHLLVI
                     GPTFSEYAAAMARVGGQISSIMATRDDGYRPPLEQALDNLDKFRNKGNSMPPVDAVML
                     CNPNSPTGQACDAVMVRKLARRAARLGQWCLVDETFAEYCEQVSILPEDLPARTLVLR
                     SFTKFYGLPGLRVGYAVGNPKVIKQVSAHQPPWSVNMLAQRAAQLALQDRRHSRRSLR
                     FIEQERSRLVQELRRLPGCSTFPSAANFLLVELPARLKATRVVSALRRQGILVRDCSQ
                     VPGLNDRSIRLAVRSRADNDRLLNSLSKIIGNSRV"
     gene            12423..13157
                     /locus_tag="PK063_15670"
     CDS             12423..13157
                     /locus_tag="PK063_15670"
                     /inference="COORDINATES: protein motif:HMM:NF014060.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide amidohydrolase"
                     /protein_id="HMZ98538.1"
                     /translation="MTQRHANRISTRHWVAGDTLIVDLGVRMRVLSSAPRGGGLRTTR
                     FILNHQVPSHPPGTDTTGRTWEHPSHYLRRLAETHGVEPDCVGLMTAVPMTQLVTHRE
                     ERDGTWVEGFATVGVTNAVRAGEPVRQVQGEQIGATAGTINLIVVTNGCLAVPAMVGA
                     VQVATESKTGVLRDHAVPSWTGLAGATGTGTDAVVVASALRGRGPWYPYAGTHTEIGS
                     MIGRVVAECLLQGLALAAQWADQRRT"
     gene            13173..14726
                     /locus_tag="PK063_15675"
     CDS             13173..14726
                     /locus_tag="PK063_15675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HMZ98539.1"
                     /translation="MPHPSRAKAIAILGTGSDVGKSMVAAGLCRLLHRAGIRVAPFKA
                     QNMSLNSFATPEGGEIGRAQALQAEACGLAPHVDMNPILLKPESNARSQVVVQGKVFA
                     TLDARDYFTRGQDSRLLRAVRESYERLAAQYEVIVIEGAGSAAEVNLRDRDLVNWTTV
                     ELADARVVLVGDIDRGGVFAQIVGTLDLIAAEERARVCGIVINKFRGDRTLFDEGVRF
                     LTARTGIPILGVLPYLRDLALDQEDGLDVDAGAQIPFTAERVNVAVLLLPHMSNFTDF
                     NALAQETDVALRYVATPEAALGADVMILPGSKTTLSDLAYLRERGFQSVLQDHVRRGG
                     ELVGVCGGYQMLGQSIADPDGVETGGHDKGLELLPVTTVLARDKITEQVEGQALHIEG
                     STTLTVRGYLIHVGRTDRAGLRPSFQLVRRKTSLDGSTAIVRDEECLDGAVGHDGLVW
                     GTYVHGLFDQPDFRRAWLNRLRSRKGLPAVSLEESQRVNDTRLNAMDRWADHVDRHLD
                     LAPVLSWLR"
     gene            15136..15870
                     /locus_tag="PK063_15680"
     CDS             15136..15870
                     /locus_tag="PK063_15680"
                     /inference="COORDINATES: protein motif:HMM:NF023273.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3365 domain-containing protein"
                     /protein_id="HMZ98540.1"
                     /translation="MANHFFHRIAMAVLAAACVGGPVAASANTEVETAELLIKLLQVG
                     RGVLSENQATINDASKGDKGFTGDYVANQVIDRFRKATKIDLSRPATVPQAPLFLAMV
                     ESEKEVIDEAQPVINKQGVGFKGIIPAVFARKSGERFYRKTGIRVKLTSIDYRFPGNR
                     PDDFESEVLRIFSDSRHPKGQPYSKATMLDGRPVLRMMDPEYAATTCLSCHGNPKGER
                     DVTGAKKEGWHEGDLAGAISIVIPMK"
     gene            15936..16298
                     /locus_tag="PK063_15685"
     CDS             15936..16298
                     /locus_tag="PK063_15685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ98541.1"
                     /translation="MSKIVVVDDSYAELQLIEGYLKSANHTVVSYPNTDKLEDKLALD
                     KPDLIVLDVVMPGRNGFQACRDLKSDDRFKGIPIVLCTSKGQESDKFWGQQQGANGYV
                     VKPFKAEDLVAAVKRALN"
     gene            16302..16847
                     /locus_tag="PK063_15690"
     CDS             16302..16847
                     /locus_tag="PK063_15690"
                     /inference="COORDINATES: protein motif:HMM:NF013731.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HMZ98542.1"
                     /translation="MSDVPIIQPQASATSPAQGSSGSSRTSAASTEGALRMCVLTLGG
                     ELFAIDLRHVSEVFEVEAVTAVPSMPSYLTGVTNLRGTVITLVDLRGSLGLSVNNTAL
                     PFAVVIRHGARQVGVLVDHVPEIHTVPREHLLPAMQAGPAGARPCVSAVLRVDHRLGG
                     VLEVPQVFAQVDGGSAALSVV"
     gene            16943..>17565
                     /locus_tag="PK063_15695"
     CDS             16943..>17565
                     /locus_tag="PK063_15695"
                     /inference="COORDINATES: protein motif:HMM:NF024140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MCP four helix bundle domain-containing protein"
                     /protein_id="HMZ98543.1"
                     /translation="MIGQGVTNRFQDMKTRSKLLLSFGLVSFIIMIMASVGVFTLRQL
                     SAQSQTVYVDYTVPLAEFAQMGTALTKHHQILLDVASATKQSDFAQEITKLPPLKAEI
                     EKAINNYKSTNLRVSRSGRDEMKDLTLFEPALKKYFQEADGALSAMADSFDRNTLSPA
                     QAEQMRALGILALTVNLTPSFENAVRRHNEQVSSIESVAKDLNDDAQS"
BASE COUNT         3399 a         4804 c         5698 g         3664 t
ORIGIN      
        1 ggcgtcacag acttctgcaa ttttccggca gccgccgccg cgaaaccgaa agtcggctac
       61 agcaatccca acctggaatc gctgatcgcg ctccgtccag agctgatcgt ggcgccgctc
      121 gagtttcatc gtgccaatgt gctggccaag ctggaggaac tgaaaattcc ggtgctcctg
      181 ctcgaagcca cgtcgttgga acaggtgttt gcgcacattc atacattggg gcggatcttc
      241 gatcgctcga ccgccgccca tgcgatgacc gcagagatgc ggcaacaaat ggcggagatc
      301 agtcgccgaa cagaaggcct ggcgcgtacc agggtgttgt acgtcatcaa tagccagccg
      361 ctgatcacgg tggggccagg cagttacatc catcagatga tcgggttggc gggagggacc
      421 aatatcgctg ccgcagcggc cacggcctat ccgcgtctga cgatggaaac ggtgttgaag
      481 gaagatcccg agattctgat ctttccacgg gggtctgtcg agacggtgcc gcgaagcgag
      541 caggaggcct ggcgacgctg gaccacgctg acagccgtgc agcagaaccg cctccgggaa
      601 gtgtcggcgg atgcgctcaa tcgaccaggc ccgcgcgtca tgcaggggtt ggaagcactc
      661 gccagggtca tccatcctga agcgttcgat tctgaaccga tgacaatcaa gccatgatgc
      721 catctgccgg tcaccccacg tcacctcctc cagcgctgac ttcgccatcc ctctcgccca
      781 atctcatgca atccggtccc agctttaccg cgactgatcg gccgtttcag ggcgcgatcc
      841 tgactcgttc gcgctggtgt gccgtgatgg gggcattgct gctgctctcg gtgattcttg
      901 ccatgctgtg tttacagctg ggaacccagt acatcggcat ggggcacatt ctcactctcg
      961 tatggtctgc cgtagtcggg acctcgaacg aaccggatgc gctccggacg acgggggtga
     1021 ttctcctgca ggtcaggttg cctcgcgtgt tgctgggatt tttggtcgga agttgcctgg
     1081 cggctgtcgg agtgtcgctg caggcgctgc tcaggaatcc cttggctgat ccctatgtgc
     1141 tgggagtgtc gagcggcgcg gcgctgggcg tcgccatcgc ggtcctgttc ggaatcggca
     1201 ccacagtcct cgcgttgtcg ctcttacctg tctgcggatt tgcgggcagc ctggtggcgc
     1261 tgttggtcat ctatcgcatg gcggcgtcct atgagcgact cccgatccat tcggtgctgc
     1321 tggcaggcgt catcctcaac gccatctttt ccgccctcat tatgttcatc acctccatca
     1381 tggagccgaa ccgctcattt gggatgatgg cgtggctcat gggatcgctc acggcgccgg
     1441 cctatccggt cctgatcgca ctctccgtct atttgctcgt cggcctcgtc ctgctgggga
     1501 agcacgtccg ggtgctcgac attctcgcct tgggtgaaga acccgcgcga tcgttgggta
     1561 ttaacacgga acggaccaag cgcgtcatat tcctcttgtc agcgctcatg accggggctg
     1621 tggtgtcctt cagcggcatg atcgggttca tcggcatgat cattccacat gcggtgcgtc
     1681 tggtggtggg ggcggatcac cgattgctcc tgccggcatc cacgttggtc ggagggatgt
     1741 tcctgatggt ggcggatacc atggcacgta ccctgttcgt cccatccgaa gttccggtcg
     1801 gcgtcattac ggcgttagcg ggtggtccct tcttcgtgta cttgctggtc tggagaaagg
     1861 atcgtctggc gtgagcaggc atctccaggg aaaagcacgt atcgataccg gggccggcat
     1921 tggtacggat gcccccttgg cctatgatgt gtgcggagcc tatttctgct acggcagact
     1981 cagcacgctc gacgtcaggt gggtgctcca gaatgtgacg gtgcaggttc aatctggcga
     2041 aatcctcggc atcgtcggtc ccaatggttc gggcaaaacc tctctgttga aactattggc
     2101 caagctcgca gcacctcaac gaggggacat cacattgttc ggtcagagcc tggctggcct
     2161 gtcgcaggac gacacggcgc gagccgtcgc gtgtgtgcca caggagaacc cgcagctatt
     2221 tccatttacg gtggcggaaa ccgtgttgat ggggcgattc ccgcatcgcc atcggtcgcg
     2281 ctggagcctt ggtttcgggt gggaggacca ggatgattgt cgggcagccg cgcaggccat
     2341 ggagacgatg gatattacgc atctcgcctc acggctggtc accgatctct ccggcggtga
     2401 gcgccagcga acgatgatcg cacgggccct cgcccaaatg cctcgcgtat tgctactgga
     2461 tgagccgacg gcgtttctcg atcttcagca tcagctcgac atttgctcgg ttgtgcgtcg
     2521 attgcgtgag gagcgggggt tgacggtggt catcgtgtcg catgatttaa atctggccag
     2581 tcagtactgc gatcgcatcg cgatgctgaa agacggcagc gtggccgcga tcgggacgcc
     2641 ctcagaggtc atgtcagtcg aaaccttgcg tgaggtctat ggctgcaccg tgctgatcga
     2701 tgcgcatccc gattcgggat tgccgcgtat cacactgccc gggcctgccg tgccggttca
     2761 ccgataggaa cggaacgttg cggaggggtt cgtgcccggc ccacccgcgt gatgagaagg
     2821 ggcatgtcat cattggagaa cggagtatca ggaagacgcc gtcagcgtcg gggaagatgg
     2881 tgcaaaacca tcacggtgcc gccactgtaa gcggggagtg accctgcagg aagccactgg
     2941 cgagcgacgt gattcgtgaa tcatcccttg tgaagcgcaa gaggtttcct ctgaccgttt
     3001 cacgatgact cacgtctcac gccgtcggga aggcgcaggg aagccaggat ccgcaagtca
     3061 ggagacccaa ctgacgggtg ttacgactga gcccttcgag cgaaagggaa cgtcagcatg
     3121 ttgaagcgtg tcagggaatg gtctgtctgt tgtctgttgc tgttgatcgt gagcaccccg
     3181 cctgtctggc cggcggtcgc cggtgccgaa gaaccggagg agcctgaacc ggtcgtgcag
     3241 gccgaagaag tcgtcatctc agccacgaaa acaccggtcc ctgtgacgca ggtgaccagc
     3301 gccgtcgaag tcatcacggc gcaagacatg aaaaagcaaa atatccggca cgtggccgac
     3361 gccctacggt tggcgcaagg gctggccgtg ttttcgagcg gcggaccggg aacggaggtc
     3421 aacgcaagaa ttcgcggggg aggttccagc cagacgctgg tcctgatcga cggcgccatc
     3481 gtcaacagcg gaacgttggg cagctatgat ttttccaacc tgaccaccga caacatcgag
     3541 cgagtcgaaa tcctgcgcgg cgcgcaaagc atgttgtggg ggtcggatgc gatgggcggc
     3601 gtgatcaata tcgtcacgaa gcgaggcgag gggccgctta ccgcgaccgg tttcatggaa
     3661 tatgggtcct tcgcgacgtt gcgcgagggc ggcaccgtat caggaaagca gggactcgtc
     3721 gactacagcc tttcgctgtc ccgttgggac acctccggct tttcggccgt caattatcgc
     3781 cgcggcgcga ccgagcggga ttcctttcgt aattggcagg gatcggggcg catcggcgtg
     3841 gatctcccgc gtgatggtcg actcgatttc accatgcgct ggatgaattc cgatacccaa
     3901 ctcgacaatg tctcggcgac gtttccggcg gatgtctacg ggtcgaagat gcgcagtcag
     3961 cagtatgtgt tcagcgggag ttatgagcag ccgatcaccg gctggtggtc ccagaagctg
     4021 acactcgcac gatcgcagga agcttcgctg tttctgccgg ggactgtaca gcggagcctt
     4081 gtcgacggat tcatcagcac gccgttcgga tctccgaatg aaacgcgtgt cctttccaat
     4141 cgcctggagt ggcaacataa tttccaggtt accaggctgc tcctgctcag cgcagggtat
     4201 caattccggg aacagcaggg tgaaaacgac acgggcctga tcaatcgcgt tttgagttcc
     4261 cacgccggat ttgcgcaggc gcagttcaat ctctgggatc gtgtcttcgc gacggccggt
     4321 gtgcggcacg acagttacaa cgtcttcggc aatgccacca cgtatcgact caccggcggg
     4381 tactaccaga aggaaaccga tacgaaattg cgcgtcggct attcgaccgg cttccgggca
     4441 cccagcatga atgagctgta ctttccgaac ttcgggaatc ccaatctggg accggagaag
     4501 aaccaaagta tggacgcggg gatcgatcag tatttttttt cgaaacagtt gaagctgagc
     4561 ggaggcttct tctggaatca ttatcgcaat ctcatcgtca cgacctttga cccggggttt
     4621 tgcgccccct tcagcacgtt tggattctgt ccgcagcaac tgggggaggc atcgaccaag
     4681 gggtgggagg ccgggctcac ctatacctat tccagcgatc ggccgtttct gaaaggcgtg
     4741 gtggttcagg cgcagtacac gaatacgatc acgcgcgatc tggatacgca aacgcgtttg
     4801 ccacgctggc cgaccgacca gtggagcgcg tccgtgagct atcaaccgat cgaccccttg
     4861 tggatcacgg tgatcgggcg ctatgtcggg tcgcgattca atacgaccgg tgatcggcaa
     4921 gccatgccgg cgttcgacgt gtggtccctc gccgtgacct acgatgtcac gaagcagatg
     4981 caagcctatc tgcgagcgga gaacctgttc aatgagaagt atgaagaaat cgccagtgcc
     5041 gggacgccga tccggtcgat tttcggaggt cttcgcgtga cgttcggcgg taaatcgtaa
     5101 atggtccatg agcatcgtct ggtgatgcca cgccctcgtc tggtcattgc cggcacccac
     5161 agcggtgtcg gcaaaaccac cgtcaccctt gcgctgatgg ccgcgttgaa ggccagaggg
     5221 ctggtggtgc aaccgttcaa ggccgggccg gattttatcg atcccggaca tcatcagctg
     5281 gtgaccggtc ggccctcgcg caatctggac gggtggatgt tgaatgaggc ggtcaatcgg
     5341 tcgatctttt cgcaggcgtc ggccgatgcg gatctgtcca tcatcgaagg gatgatgggc
     5401 ctctttgacg ggagttcccc gatacacgag cagggcagca cggcagaatt ggccaaacag
     5461 ttgcatgcgc cggtgttgtt ggtgattgat ggcagcgcca tggcgcgctc ggcggcggcg
     5521 atggcagccg gatatgcgcg attcgatccg ggcctttctg tgcagggcgt gttgttcaat
     5581 cgagtgcgaa gcgacgggca ctaccgcttg ctccaggagg cggtggaagc ggagacgggg
     5641 ctcgccgtcg tcgggtacct tcggcctgat gcctcggtta cgatccctga ccggcatctc
     5701 ggtctcagga ccgccattga ggcagggtca tgtgacctct acgaccgact ggcgcagtcg
     5761 gctgccgaga cgattgatct ggctcgagtg gaggcgatcg cccgatcggc tgaaggatgg
     5821 tttgaagaag atccggtcag tccacctgcg gcaggaccga aagaaacggt ccgtgttggt
     5881 gtggcctatg acggtggatt ttgcttttac tatcaggaca acctggaatt actcgcagcg
     5941 gccggtgctg agatcgtaca attctcgccc ttgcatgatg cagctctgcc ggatgtggat
     6001 ctgttgtatt tcggcggcgg ctatcctgag ctctatggtg aggcattggc tgccaacgtg
     6061 agcatgcggg ccgcggtgaa ggcgttcagc gaccgcggtg gagtgatcta tgcggaatgc
     6121 ggcggcttga tgtatttgac gcaagccatt cgtgatggag acggtcatcg ctatgagatg
     6181 gtcggtgtct ttcctgccga ggcggtcatg cggaggtcgg ggatgacgtt ggggtaccgg
     6241 atcgtcgaaa cgatgcggcc ctctctgctg ggcccggccg gcacgtcagt gcgcgggcat
     6301 gagttccatt attccctcct cgagccgaag ggcgagttgg cgtatgcctg tgtgctggca
     6361 gatgcagcgg gcaagccggt tggtcaggat ggcgtgatgg tcagaaacac cttggcattg
     6421 tatagtcacc agcatttccg gagccgtccc gaggtggtgg tcaatctgct ccagtctgtg
     6481 cgacaagaga aagctgcgcg ccaagcatga ggaagcagtg agatgactga tcgggatgaa
     6541 cacaccgcca aaatgcagcg cctgaaaggg tcggtcgatc gtcgtatcga agcagctcag
     6601 gaggaaaagg gactgctgat ggtctacacc ggcgcgggca agggcaaaac aactgccgcg
     6661 ctcggtatgg cgattcgctg cctcggtcat ggcatgaagg tggcgattgt gcaattcatc
     6721 aagggggcta tcgatacggc ggaggaacgt attcttaggt cattcggcga tcgcgtgatg
     6781 tttctgcgca tgggcgaagg gtacacgtgg gaaacgcaag atcgcgaacg cgatacgaga
     6841 ttcgctcagg aggcctggaa caaagcctgc gagttcatga ccgatccctc ctatgcgatg
     6901 gtgattctcg acgagttcaa cattgccctg caccaccact atgtggagct ggcggaagtg
     6961 ctgccgcgat tgcaggctcg tccgctgatg caacatgtgg tcattaccgg tcgaggggct
     7021 ccggctgagc tgatcgacgc ggctgatttg gtgaccgaga tgaaacaggt caaacatccc
     7081 tttcgacaag gcattaaagc gcaggcaggg gtggagtttt gagaggcccg gtgagcaaga
     7141 cgtgcgagca ttgccgtcag ccgttcgagt gtgtcgggta ccaatgttgg tgcgggaaga
     7201 tcggcattac cgaagcccaa atggattgga tcgccgcccg ttatcaggat tgtctctgtc
     7261 ccgcgtgcct gcaacaggtg gccgatggaa agcttggacc gggagtgccg cctcaggcag
     7321 atcaagcgag gtaacgtgtc gataccgggg ttcggcctcg tgagtcgagt ggcgaatccg
     7381 gagtgaaagg atcagagcat gcgaattacc aaagtctata cacgaaccgg cgacgcgggc
     7441 caaacaaggc ttgccggagg gcagcaggtc tggaaagact gtgtgcgcgt tgaagcctat
     7501 ggcaccgtcg atgagctgaa tgcctctgtg ggattggtgc gggcgatgaa tgccgaaggc
     7561 gggagcgcct ctcccgcctc cgcgcaactc gagacggact tgcgctggat ccaaaataaa
     7621 ctgttcgatg tcgggagtct gctcgccacc gcgccgggcc agagctttcc gaatatgccg
     7681 aaagtcaccg aggctgacgt gaccaggctc gagcagatga tcgatcgctg tcaggaagac
     7741 ctggcaccgc tcaaggaatt tattctgcct ggcgggggga aagtgtcggc gacgctgcat
     7801 caagcgcgca cgatctgccg gcgggccgag cgcgattgca tccggctcag ccgtgaggaa
     7861 gacgtgtccg ccgagctcaa taagtacctg aaccggttga gcgatgcctt gttcgtcatg
     7921 gcacgatggg tagccaaaac ccaaggtgag ccggagtttt tgtggcagcg tgaatctgat
     7981 gccccgatca agtaaatcga cgaccaggcc cgggcgtgca gggtcccgcc tcattctggt
     8041 gctggggggc gcctcctcag ggaaaagcca ggcggcattg gaacgggcag gcagccaagc
     8101 gccaaaggcc tttgtcgcga ccgggcaggg attggataag gaaatgcagg cgcgtattgc
     8161 gcggcaccgg gcgacacgtt ccgccgagtg ggtgacggct gaggtgccac gagatctggc
     8221 gggctggttt cgatcggacg gatcgggcta tcgcacaatc gtcgtcgatt gcctgacgct
     8281 ctggctcagc aatgtctgcg gccgccgtct tgccggcgca gacatgagtg ctcgagtcga
     8341 tgaacttgtg cacgccattc gacagagtcc cgcgcgtgtt gtgctggtca gcaacgaact
     8401 gggattcggc ttggtgccga caagtcgcag cgcgcgcgcc tttcgtgatg tcgccggacg
     8461 ggtcaatcag cagatcgccg cctcagctga cgaggtctac tttgttatca gcggtcagtc
     8521 gctcaggctc aaataaatag gagagatgat gacactcgat gaggcgatgg gcctgattca
     8581 accagtgaat ggtgacagtg cggcgaacgc tcagcgacgc cttgatcgac tcaccaagcc
     8641 gttgggcagt ctagggcggc tggaggagtt ggctgtgcac tacgccagga tcacgggcga
     8701 tgtgaagccg aatgtgccgc gtggcgtcgt gtttaccttt gcggctgatc acggcgtggc
     8761 gatggaaggt gtgagcgcct atcccagtga agtcacaccc cagatggttc tgaatttcct
     8821 gcggggcggt gccggggtga atgtactggc acgacatacg ggagtggaag ttcgggtcgt
     8881 ggatatcggt gtcgcctacg acttcggggt cgtgcccgga ctcattcaga aaaagatcat
     8941 gcgggggacg aacaatctcc tgcgtgaagc ggccatgacc agggcgcagg cgacggaggc
     9001 attgcaggtg ggaatcgatc tggcgacgga ggctgcgcag gagggggtcg gccttatcgg
     9061 gaccggggaa atggggatcg gcaacacgac tccaagcgcg ggcatcacgg ccgtcatgac
     9121 cggtcgaccg gttgctgaag tgacggatcg tggaaccggc atcgacgaag ccggtcacgc
     9181 ccgcaaggtt tcggtcatcg agcaggcgct gaatcggcat cgtcctgata aagctgatgc
     9241 gcttgatgtg ctggccaagg tgggcggact ggaaatcgcc gggctggccg ggctcatgct
     9301 aggcgcggcg gcagcacgcg tgccggtggt gttggatggg tttattgccg gtgccgccgc
     9361 cttgatggcc gtcgcgttgc agccgttgtg tcgtgactac ctgattgcgt cgcaccggtc
     9421 ggtcgaacgg gggcatcagg cgactctgga atgtctggct ctgaagccgc tcctcgatct
     9481 ggatctccgg ctgggggagg ggacgggggc ttgcctgggg atggggctcg tccaggcctc
     9541 aatcaaaatt ctcaccgaga tggcgacctt cgatgaagcg ggtgtgacgg aacgtgactg
     9601 aaattgccgc catgacgaga ccgtttgtgt tcgcctggca tttcttgacg gcgatcccca
     9661 tcagccgaac tcatcacgcg ccgacggctc aggagttggc gtcatcgatg gcctggtatt
     9721 ccaccgtcgg tctcgcgatc ggcggcctgg tggcgttggc cgatgttggc ttgcgctcgt
     9781 ggatggcagc ggaggtcggc aatgcgcttt tgattgtgct gctcgtgctg ctcacgcgcg
     9841 ggttgcatca ggatggcctg gcggacacgg tcgatggact ggccggcggc cgaaccgttg
     9901 aggatcgttt gcgaatcatg cgcgatccgc gagtcggtgc gttcggcgcg accgccttga
     9961 gtctttccct gttgctacga tatgcagggt tactggcgct gcctgcaccg ctgcgactgc
    10021 cggtgctgct gtgcatgccg gcactgggtc gctgggcgat ggttagtttg gcatgggcgt
    10081 cgccctcagc aaggcgtgat gggggattgg ctgcctcgtt tctcacgcac ctgtcctggc
    10141 aacaggttct tctttcgagc ctcgtattgg ctgtggcgtt gacgatggcc ttgggcggaa
    10201 ctgtggcggt cgcgaccatg ggcatgggtg tcctgttgct ggtcctgatc aggcagcggt
    10261 gtctgacctt gcttggcggc gtgacgggcg atgtgctcgg agccacgaac gaagtggtcg
    10321 agatgctctt tctcttattg attccggcgt tggtggtagc cgcatgactg gtgtggagtt
    10381 agcagtcgcc gcggcgctgg atgtcgcggc gggagatcct cgctggttgc ctcatccggt
    10441 gaagggcatg ggagccgtca tcgcctgggt ggatgatcgt gttcgccgcc tttgccggag
    10501 tgagcaggcc ctccagattg cggggggctg cctggcgctg ggcttaccga tcgcggtgta
    10561 tgccgcggca acttgggtga ttgcgcaagc cacggcgatc gctcctctgc tcgggcaggt
    10621 ggtcggcgtt ggattggcat atacgacgct ggcggggcgg gacttgttcg accacgttca
    10681 ggcggtgctc cgtgaattgg ctgccggcaa tctggccggt gcccgccaag ctgtggcgat
    10741 gatcgtcggc cgtgatagtg ccacgctgac agagtccggc gtggcccggg ccacggtgga
    10801 aaccatcgcg gaaagtacat ccgacgggat cattgcaccc ctggtctatc tgtccctggg
    10861 cggggcgccg ctggcgctgg cctataaggc ggtcaatacg ctcgactcca tgatcggtca
    10921 cctggatgcc cggtatgagc atttcggttg ggcctccgcc cgactcgacg atgtgctgaa
    10981 ttgggtgccg gcacgattgg ccggcggctt catcgcactg gctgcaggcc tatcaacagg
    11041 ccaatggcat cggattcatg aaagttggta catgctccat cgagacgggg ataaacacgc
    11101 cagtccgaac agtggccagc cggaagcagc catggccggc gccttggccg tgcaactggg
    11161 tggaacaaat tattatgacg gtgtggcgca cgaagctccc tccatcggtg acggaactgc
    11221 cgacatcact ccgcagcaca tccgccaggc gtctcgcatc atgatcgtga cgtatggtct
    11281 gggtctgttc ttcgccctgc tttccctatg ggtatcatga accgccaggc tcatgggggg
    11341 gatgtctatg cggcggctcg tgaattgaag cggaatgtcc ggcacctgct ggatttcagc
    11401 gcgagcatca atcccctggg gccgtcccct gcggcgtggc gagcgatcgg ccgggggagt
    11461 gaactgctca gccattaccc ggatccggcc tgtcgggatc tacggcaggc gttggccaca
    11521 ttttgggatc gttcaccgga agaatttctg atcggcaacg ggtcaacgga attgattcac
    11581 ctgcttcccg aggccttgca gatcaggcat ctcctcgtta ttggtccgac gttctcggaa
    11641 tatgccgcag ccatggctcg cgtcggtggg cagatcagca gcatcatggc cacacgtgac
    11701 gacggatacc ggcctccgct tgagcaggcg ctggacaatc tggacaagtt ccggaacaag
    11761 ggaaacagca tgccgcctgt tgatgcggtg atgctgtgta accccaacag tccgaccggc
    11821 caggcctgcg atgccgtcat ggtcagaaaa ttggcccgcc gggcggctcg tcttggacaa
    11881 tggtgtctcg tggatgaaac ctttgccgaa tattgcgagc aggtctcaat tttgccggaa
    11941 gacctgcctg cgcggaccct cgtgttacgc agcttcacca agttttacgg attgcccggt
    12001 ctccgtgtgg gctacgcggt ggggaatccc aaggtcataa aacaagtgag cgcgcatcag
    12061 cctccctggt cggtgaatat gctggctcag cgagcggctc aactcgcact gcaggacagg
    12121 cggcacagcc ggcgaagcct ccgattcatt gaacaagagc gatcgcggct tgtgcaggag
    12181 ttgaggcgat tacccggctg ttcgacgttc ccgtccgcgg ccaatttcct actcgtggag
    12241 ctgccggcaa gactgaaggc cacgcgcgtg gtatcggccc ttcggcggca aggaattctg
    12301 gttcgagact gttcgcaggt gccgggactg aatgatcgtt cgatacgcct ggccgttcgc
    12361 tcgcgcgccg acaatgatcg cctcctcaac tctttatcca aaatcatcgg gaatagtcgc
    12421 gtatgaccca gcgtcatgca aaccgcatct cgacgaggca ttgggtcgcc ggcgatacgt
    12481 tgatcgtgga tctcggcgta cgcatgcgcg tcctctcctc ggctccccgg ggcggagggc
    12541 ttcgcacgac tcgttttatc ctgaatcatc aggtgccctc acatccgccc gggacggaca
    12601 ctacagggcg aacctgggaa catccatccc attacctcag gcggcttgcg gagacgcacg
    12661 gcgtggaacc ggactgtgtc ggactcatga cggcggttcc catgacgcag cttgtgaccc
    12721 atcgagagga gcgagatgga acgtgggtag aggggtttgc caccgtgggg gtgacgaatg
    12781 ccgtgcgggc cggggagcca gttcgtcagg tgcaaggcga acagatcggt gcgacagcgg
    12841 gaacgattaa cctcatcgtg gtgacgaacg gctgtcttgc ggttcctgcc atggtgggcg
    12901 cggtgcaggt ggcgacggag agcaaaacgg gcgtgttgcg cgatcatgcc gttcccagct
    12961 ggaccggact tgccggtgcg accgggacgg gaacggatgc ggtggtggtc gcctcggctc
    13021 ttcgagggcg tggcccctgg tatccgtatg cggggaccca tacagagatc gggtcgatga
    13081 tcggtcgcgt cgtggctgag tgtcttctcc aaggcttggc cctcgcagca cagtgggccg
    13141 atcagcgtcg gacctaacct ccgagctttc tcatgcctca tccttctcgt gccaaagcca
    13201 ttgcgattct cgggaccggc tccgatgtcg ggaagagcat ggtggcggca gggctctgcc
    13261 ggctgctgca tcgcgccgga attcgcgtgg ccccctttaa agcgcaaaac atgtcgctga
    13321 actcattcgc cacaccggag ggtggcgaga tcgggcgtgc ccaggccttg caagccgagg
    13381 cctgcggcct tgctccccat gtcgacatga atcccatcct gctcaagccg gaatcgaacg
    13441 ccagatcaca agtggtggtg caggggaaag tctttgcgac attggatgca cgcgattatt
    13501 tcacgcgcgg gcaggattcc cgcttgttgc gcgcggtccg cgagagttac gaacggctcg
    13561 cagcgcaata cgaggtgatc gtgatcgaag gagccggtag tgccgccgaa gtgaatttgc
    13621 gcgaccgtga tctcgtcaac tggactacag tggaactggc ggatgcccgg gtggtgttgg
    13681 tgggtgatat cgaccgcggc ggcgtcttcg cccaaatcgt cgggacgttg gacctgatcg
    13741 cagcggagga gcgcgcccgt gtctgcggga tcgtgatcaa caaatttcga ggggacagga
    13801 cactcttcga cgagggcgtc cgttttctca ccgcacgcac aggaataccc atactcggag
    13861 tgttgccgta ccttcgcgat ctcgcactgg accaggagga cggtcttgac gtagatgccg
    13921 gggcgcagat tcctttcacg gcggaacgtg tcaatgttgc cgtgctgctc ctgccgcaca
    13981 tgagtaactt caccgatttt aatgcgctcg cgcaagaaac ggatgtcgcg ctgcgatatg
    14041 tcgcaacgcc tgaagcggca ctaggcgcag acgtcatgat cctgcccggt tcgaagacca
    14101 cactgtcgga ccttgcgtat ctgcgcgaga ggggatttca gagtgtgttg caggaccatg
    14161 tgcggcgtgg aggggaattg gtgggcgtgt gcggcggcta tcaaatgctt ggacaatcaa
    14221 ttgccgatcc cgatggagtt gagaccggcg gtcacgataa ggggttagaa ttgttgccgg
    14281 tcaccaccgt gttggcgcga gacaaaatta cggagcaggt cgaggggcag gctctgcaca
    14341 ttgagggatc aacgactttg actgtccgag gatatctcat ccacgtgggc agaacggatc
    14401 gcgcggggct tcgtccctcc tttcagctcg tgcgaagaaa gaccagtctg gacggcagca
    14461 cggcaatcgt tcgcgatgag gaatgtctgg atggtgcggt ggggcatgac gggttggtat
    14521 ggggaaccta tgtccatggt ctcttcgatc aaccggattt tcgccgtgct tggctgaatc
    14581 ggctgcgcag ccgcaagggg ttaccggcgg tttctctgga agagtctcaa cgcgtgaacg
    14641 acacacgtct gaacgcgatg gatcgctggg ctgatcatgt ggatcggcac cttgatctcg
    14701 ctccggtttt gtcatggctc cgatagtctg atcagatttc gtctgacagt gtctagccat
    14761 tccagctcca cgtcattttg acacttctcc cgtcaagcga ccaaactttg gcgctccgct
    14821 cgaaatgttg aacaattgag aaccctgctc agacgcactg atcatagtgg gtatagttga
    14881 tcgtccacat ctaatcatac gcaaaatcgc cgacttcatt tcattccact cctcccctgg
    14941 tcgaagatac taagtaattg ttttgtttgg caccgaacgt gcacgaggca ggccggggct
    15001 gcaggggctg acgtacctgt cacgaggcca aaaattgtca atcgctaatt ttgcgctatc
    15061 tttgacagag gtttggcgca gttagtacga gcggattcct cacgagcgac atcgagatcg
    15121 gcaggaggag ggggcatggc aaatcatttt tttcacagaa ttgcgatggc tgtcctggcg
    15181 gcggcctgtg tgggcgggcc cgttgccgcg tcggctaata ccgaggtgga aacggctgaa
    15241 ttattaatta aattgctgca agtcggccgc ggggttctgt cggaaaacca ggcgacgatc
    15301 aatgatgcca gtaagggcga taagggattt accggggact atgtcgcgaa ccaggtcatc
    15361 gaccggtttc gtaaggcgac gaagatcgac ctgagccgcc cggccaccgt gccgcaagcg
    15421 ccgctgttcc tggctatggt cgaatcggag aaagaagtca tcgatgaggc gcagcccgta
    15481 atcaataagc agggcgtggg cttcaaaggc atcattcccg ccgtgttcgc acgcaagtcc
    15541 ggcgagcggt tctatcgcaa gaccggcatt cgcgtgaaac tgacgagcat cgactatcgg
    15601 tttccaggca accgtccgga tgattttgaa tccgaagtct tacgcatttt ttcagactcg
    15661 cgccatccta agggacagcc gtacagcaag gccaccatgc tggatggaag accggtgctg
    15721 cgcatgatgg atccggagta tgccgcgacc acatgtctca gctgccatgg gaatccgaaa
    15781 ggcgagcgtg atgtcacggg cgcgaagaaa gaaggctggc atgagggcga tctggccggc
    15841 gccatcagca ttgtcattcc tatgaagtag gcacgacggc gcagtccaga caggcgtcga
    15901 aaacttttga atggttgtga aggggggatg gattcatgag caaaatcgtt gtggtcgatg
    15961 attcgtacgc cgaactgcag ttgatcgaag ggtatctcaa gtctgccaat cataccgtgg
    16021 tgtcctaccc caataccgac aagctcgaag ataagttggc gttggataag ccggatctga
    16081 tcgtgttgga cgtggtgatg cccgggcgca acggattcca ggcctgtcgc gacttgaaga
    16141 gtgatgaccg gttcaagggt attccgatcg tgctgtgcac ctccaaggga caggaaagcg
    16201 acaagttttg ggggcagcaa cagggggcga acggctacgt agtgaagccg ttcaaggccg
    16261 aagatttagt tgccgcggtc aaacgggcat tgaactaact catgagcgac gttccaatca
    16321 tccagcctca ggcttctgcc acttctccgg ctcagggatc ctccggttca tcgaggacat
    16381 ctgccgcatc gaccgaaggc gcgctgcgca tgtgcgtgtt gacgctggga ggagaactct
    16441 tcgcgatcga tcttcgtcat gtcagcgaag tgttcgaagt cgaagcggtg acggccgtgc
    16501 ccagcatgcc cagttacctg acgggagtga cgaacctccg gggaacggtc atcacgctgg
    16561 tcgatctgcg cgggagcctt ggcttgtcag tgaacaacac ggcgctaccc ttcgcggtgg
    16621 tgatacgtca cggcgcgagg caggtgggag tactcgtcga tcacgttccg gaaatccata
    16681 cggtgccccg cgagcatctg ttgcctgcca tgcaggcggg accggctggt gcgagaccct
    16741 gtgtgtcggc cgtgctgcgc gtggatcacc ggctgggagg cgtcctggag gtgccgcagg
    16801 tcttcgcgca agtggacggg gggagtgcgg cattgtcagt cgtgtagtga ataaagctat
    16861 gacggtttgc gggtcagcgc gagcagggat tgtgcgaccg gccagcgaac attgagaaag
    16921 cagtaacaag gaggagcgca ccatgatcgg gcaaggcgtt accaatcgat tccaggatat
    16981 gaagacacga tcgaagctgc tgctcagttt cggtctggtg agtttcatca tcatgatcat
    17041 ggccagcgtc ggtgtgttca ccctgcgcca gctcagtgcc cagtcgcaaa ccgtgtacgt
    17101 ggattacacg gtgccgctgg cggaattcgc gcagatggga acagcgctca ccaagcatca
    17161 ccagattctg ctggacgtcg cctctgccac gaaacaaagt gacttcgcgc aggaaatcac
    17221 caagcttcct cccttgaagg ctgaaatcga aaaagccatc aacaactaca agagcaccaa
    17281 tttgcgagtg tctcgatcag gccgcgacga aatgaaggac ctcaccctgt tcgagccggc
    17341 cctcaaaaaa tattttcagg aagcggatgg tgcgctcagt gccatggccg acagtttcga
    17401 tcgcaatacg ctatctccgg cacaggctga gcaaatgcga gcactcggta tcttggcctt
    17461 gacggtgaac ttgaccccct cattcgaaaa cgccgtacga cgccacaacg agcaggtcag
    17521 cagcatcgaa tcggtggcga aggatctgaa cgacgacgcc caatc
//
LOCUS       DAOQPD010000085        17247 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1658_length_17247_cov_22.400186, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000085 DAOQPD010000000
VERSION     DAOQPD010000085.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 17247)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 17247)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17247
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1658_length_17247_cov_22.400186"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(321..2183)
                     /locus_tag="PK063_15700"
     CDS             complement(321..2183)
                     /locus_tag="PK063_15700"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98544.1"
                     /translation="MKTNRVVLVGIALLSLLASVGCESIKSRFSRQALPDLGPPVPLT
                     VHMEIDPSLSKAKTEYIDNCSRIHAFSIGPTVEDTLIQAAHQTFRTVTIPGSQAAGGK
                     PDVTIRVRMLDPRFKLQTDALYDRAPAELSLDALAEFFDASGAPLGERPLQATRKERL
                     QLELTQQRCDYIVDPLLQDTSTMLATQFMQEARVLLAPATPPPAAATTATPTEPSSKA
                     TAVPAAPAATPVQPLSFKATLLDENGNLIIESGERIRVRVDVVNTGTQLVQDSTVKLT
                     GPQTVLTQFPATTLATGTIPAAGSKSLEFVATMPQSPSLQRAELQVALLNASGQAAAP
                     PQTLPLSFQPTAALLEDVDHIPAATSGAQRPGDYLLAIGLSSYREQDIAARKYASLDA
                     ETVAAYFQTLGGLPQNNVRLLRDWSALRPDIEEALLDWLPAKTTKESLVVVYFAGQAM
                     VNAAGDTFLIPYDGSMGSPTRLYPLKELEAALGRLKAKQVLFVFDGTVLKNGADGRTK
                     AAAPKWLGTSGSVLHMIATTGFGKSLESETWHHGLFTYYLLRGLRGEADLNRNGEVTI
                     AEVTAYINRKVPGAARSTFKQEQQPQILPTLRGSEKGLDTVLTKPTMTFPSDQP"
     gene            2396..4129
                     /locus_tag="PK063_15705"
     CDS             2396..4129
                     /locus_tag="PK063_15705"
                     /inference="COORDINATES: protein motif:HMM:NF014589.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyltransferase C-terminal
                     domain-containing protein"
                     /protein_id="HMZ98545.1"
                     /translation="MVVLGLSNMRDAAAALVADGRIVAAAEEERFVRQKHVTALPVHA
                     MQYCLREAGMALRDVDAIAVPWKYWQVGRRLRLAVTAMLRSTQLFRVKGTRSLERASQ
                     EWKELFRLQQELSTRVEPGAGRPVFLDHHLCHAASSFLVSPFERAAILVVDGASESDT
                     TLLATGEGNQISVLERTPLPHSLGQFYAAMTAFLGFRPDQDEYIVMGLASSGEPSFAP
                     TLSREILRVLPDGRFELNTRLLDFHLARAGHFVREFIRLFGPPRRPQDEITQRHRDLA
                     ASAQFVLEETLLHLGRRLRSLTQATSLCLAGGVAYNCVANGRLRAELGFDQVYVPPAA
                     GDSGAALGAALWWTARRGAATSKTVMPDAYLGPQYDESACRAALSKTGLVAEHLADDR
                     LYERVASELAHGRLVFWYQGRMEWGPRALGNRSLLADPRREDMRELINSKVKCREAFR
                     PFAPSVLAEHAEEFFHVPAPSAFMQFTVRVKASAKGLLPAVTHVDGTARVQTVTREAN
                     PRFYDLLATFGRLTGVPVLLNTSFNVQEPIVCSPDEAVRCFQRTQVDWLVLGNLLVGR
                     PSPMPPQHHEG"
     gene            4119..5654
                     /locus_tag="PK063_15710"
     CDS             4119..5654
                     /locus_tag="PK063_15710"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98546.1"
                     /translation="MKAEPVRGSFPLPALMLILDVLLGAFVLNLVLQPLVEPDLGWHL
                     RAGLDLIAQGWRLPDTDPYSHTMPDWHWVEHAWLTDGLLGLIYRMLEPSGGLGLIAFF
                     GGVTALAWWIAAGVASVHRTCRLAAMVASLWVALPFLGARTQLISLLGVAVVLTIWNR
                     MQRGQPQWVWALPPLFLLWANLHGGFTAGLFLITVLLSLSFLVKICVEWKVVQAPRDE
                     PVLSWDVIRLCAFAILVSFAVTCLNPYGWRLYVEIYESLTDRFMIDTLREWQPVSFHG
                     WAGRAYGFYLLGFIGLMAGWYRRVEPVRWVLLALMLGLSLLHWRNVTLFLIVSLPLAA
                     ELGAAAADSFLRRVPVLQAHAAGTVLVVSIMAATALYALGTEHLEHVWQSGRTPDRYF
                     ERTEYPIEAVRWIRAHRDETGTRLYNDYSYGGFLLWQLPGERIFIDGRMPAWRIKDRW
                     IFHDYVELNREDSPQLALLDRYGVDWAMIPRGSALAVALEAHPAWKNVYADAKVVIVR
                     RQS"
     gene            complement(5671..6486)
                     /locus_tag="PK063_15715"
     CDS             complement(5671..6486)
                     /locus_tag="PK063_15715"
                     /inference="COORDINATES: protein motif:HMM:NF012745.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HMZ98547.1"
                     /translation="MTLCSTQTPSLSVIIPAYNEARRLPLFLQRVIAHLDQRGQFYEI
                     LVVDDGSQDNTAHAVRMAAHHCPHLRLIQLTCNMGKGAAVRRGMQAARGTIQLFADAD
                     GATPIEELGRLEAALAAGADLAIGSRALASHDPAFTVHARWHRSLLGGLFNHVVQRLG
                     VPHIADTQCGFKLFRQSVAQDLFAVSCVDGYAFDLELLHIARQRHYRIAEVPINWTDQ
                     PGSKVRPWRDGSLMLRELLAIRKREAQGLYQPQSRPASSAVEPDLVTVEPTHS"
     gene            6673..7437
                     /locus_tag="PK063_15720"
     CDS             6673..7437
                     /locus_tag="PK063_15720"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98548.1"
                     /translation="MRRSANCLASLVGMVIVTSCAVASPPSRLAQYVGSVVPEEAATA
                     TLPTSRPLHAALVVVADQSAPDSAPVLPDEALARVGALLTGEINRGYPVAVDRVVKLD
                     GMSPGGTAPSWPEVARQQGVQYLLVTVLSSTEQEYPISLFLGWTTHQQPGFRRDNWSL
                     AEAALIDGSTGRTVLQAEGRAMATLDRPTAPGISQWYPVIYLRPQDPERRIWPPTYEG
                     APLTLRLVSMEQAAKRLAGNLQRAWVEQRDLELAAR"
     gene            7609..9138
                     /locus_tag="PK063_15725"
     CDS             7609..9138
                     /locus_tag="PK063_15725"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Do family serine endopeptidase"
                     /protein_id="HMZ98549.1"
                     /translation="MVYRHERRRVRSVLAVTAMVAATFLSGGLPPRAGQAEAAGVPPA
                     FAQGFSEIVKAVTPAVVNIAVTGGGEGRREGRRQLPPGGPFGGPPPGPGGPGDEPPGM
                     EPPGGPPGGGPHRPEQSAGSGVILDPNGYIVTNNHVVEGATQITVTLSDRREFPAKII
                     GTDPKTDLAIIKIEAKDLSSMKWADYDELQVGDVVLAVGSPFGLSSTVTLGIISALGR
                     GNVGIADYEDFIQTDAAINPGNSGGALVNMQGKLIGINTAIFSRTGGSEGIGFAIPSS
                     IATDIVDSLTKTGKVVRGWMGVAIQEITPALAKSFKLPEQRKGVLISDVNENGPSHTA
                     GMRRGDVVISFNGKEVQSVSQLRNLVARMGVGKDADIKILREGKEQVLKVKVAERPSD
                     EVLAKREPAPSAAPAETVKPPDNVLAALRVQLLDAAMQSQLNIPAKTTGVVVSSVEAG
                     SAAESAGLQRGDVIQEVNHEVVKSLEDYQKASAKVKKDEMVVLLLSRQGNNLFVAVNP
                     K"
     gene            9230..10177
                     /gene="tatC"
                     /locus_tag="PK063_15730"
     CDS             9230..10177
                     /gene="tatC"
                     /locus_tag="PK063_15730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase subunit TatC"
                     /protein_id="HMZ98550.1"
                     /translation="MADGFKFQEWLQDTVFKPLEDKKMPVMEHLVELQVRLTRAVIVT
                     AIIFVGTFFYADTLVKWIRIPLQNMFVPGSLSWIPTDLPTVPFVFLAPAEALWQNVKV
                     AGLFALVLGTPYILVEFWHFVVPGLHAQERRFVGPFVILSTLAFYLGLLFSFFFVLPF
                     ALNFLISYGVNAGFIPQLSIAQYVGFALWFLLVFGLIFEVPLVITLLAKLGWVDAPLL
                     KRYRKWAFLTAFIFAAILTPTPDPFNQCLMALPMYIFYEVGIVSAGIFNKKKADAPAE
                     PLVPAVVAAGPGLAKAGPTIPSGGGDDEYVGVPSGGRRG"
     gene            10259..11215
                     /locus_tag="PK063_15735"
     CDS             10259..11215
                     /locus_tag="PK063_15735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HMZ98551.1"
                     /translation="MPRELNVISQPGSSSGGDACTYMWACAICDENETCQKDKEGHSR
                     WLVAKRMERIEYKVLVMSNKGGVGKSTCTTNLAVSLALKGWHVGICDMDIHGPNIPKM
                     VGAEGQKLKISTSGGIIPFQAYNMKIASMSFLLQNSDDPIIWRDAYKYEFINQLLGGV
                     EWQDLNFLLIDLPPGTGNESVTTIDLLGGVSGAVIITTPQEVALLDSRKSVTFCKDSE
                     VPIIGIVENMSGLECPHCHKEVNVFRKGGGEASAADMGVPFLGRIPLDPDVVTQSDAG
                     EPFALFNSDAATAQAYHDIANQVEAFCKKSGSLIKPAPRQQH"
     gene            11230..12528
                     /locus_tag="PK063_15740"
     CDS             11230..12528
                     /locus_tag="PK063_15740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HMZ98552.1"
                     /translation="MKSADATVGLTPLHEAQRIVLDAAAPLGLEKVSIMDTLGRVLGE
                     DIIATRSNPPWDNSAMDGFAVRAEDIAQEHAISKPVTLTVIEDVPAGKMPTKSVGKGQ
                     AIRIMTGAPIPAGADTVIKVEDTEHTPDSVRVFKAEPRGSNIRPQGEDVQKGDCIIPK
                     GTQIRSGEAGMLAILAKSFVLVYQRPRVAILSTGDELADLDERFSEEKIINSNSYGIA
                     AAVQEAGGVPILLGIARDTPAALTEKISHGLNADILVLSGGVSMGDYDFTKAVFRDLG
                     AEMNFWKLAIRPGQPLAFGKIQGKLAFGLPGNPVSSMVTFEQLVRPAMLKLSGARSYG
                     RPLLEAVFQEKFSKRTDRRHFLRGVLWREDGVFKVRTTGDQGSGILTSMVKANCLIDI
                     PVEVERLNPGDPVTVQLLSGSVWLDQAAPAASAAHRPSCC"
     gene            12550..13059
                     /gene="mobB"
                     /locus_tag="PK063_15745"
     CDS             12550..13059
                     /gene="mobB"
                     /locus_tag="PK063_15745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HMZ98553.1"
                     /translation="MSVPILSFVGRSNSGKTTLIERVIPELVRAGYKVATVKHAGHGF
                     DLDTEGKDSWRHKQAGASSVVIISKSSLAMFADVSDHMNVEDVRERYLDPSYDLILAE
                     GWRSEGYPKIVVVRDQIGEVPVSQDGLLAVVSNKPVETSVPLLDPDDVAAVAALIIRH
                     FPKSQRDDA"
     gene            13049..13756
                     /locus_tag="PK063_15750"
     CDS             13049..13756
                     /locus_tag="PK063_15750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NapC/NirT family cytochrome c"
                     /protein_id="HMZ98554.1"
                     /translation="MMRSTPAIVFGAILAGAVAFGGVAVPLTNHPKFCASCHTIQPAY
                     EGWLQSSHKEVECVACHVRPGVVGWLHDKAWHGTRDVAIYLFGKPTEPHNLQAQVDSA
                     VCLGCHRNILRVSEIAPRDLPSPVKDVGLIMSHRKHMAAFDQRAQGEGCTTCHAAVVH
                     ERPIKGYPIVIPRGHVSADSRPWNSTHPEGSVLHKRAQADCFRCHDNKTEYEGRVLSR
                     KCETCHLPEKLSEFLSF"
     gene            13776..14501
                     /locus_tag="PK063_15755"
     CDS             13776..14501
                     /locus_tag="PK063_15755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ98555.1"
                     /translation="MSSPVVEVRNLSKRFGGFTAVDGISFEIGRGEILGLLGPNGAGK
                     TTTFQMMLGLVTPTAGSIRMFGLDLQSNRETILQQVNFSSTYISLPFSLTVEENLRVV
                     ARLYGMSDIAARVDDMVKKLEMGDWRHKLTRKLSSGQMTRLTLAKALLTEPKVLFLDE
                     PTASLDPDIAHKIRAILLEERQATGLSILYTSHNMREMEEMSDRIIFLQRGKIVAEGT
                     AKDIVARFGQADLEDVFLKLARE"
     gene            14549..15025
                     /locus_tag="PK063_15760"
     CDS             14549..15025
                     /locus_tag="PK063_15760"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98556.1"
                     /translation="MVDAGISFTVGVLIGGLSLMVGWGLLWFVVGGIGLARQTSGWPI
                     FISSISSTAIAGGVMAVVFWAVDAARLSSPALHVGLAGIPLALLAASAFRLEDGRRIG
                     PAFVQGSRLMMQELLGGHQEEGGCGHCHEQPVEEHPCHQKPCFEQSCHEKPCEGKL"
     gene            15032..15823
                     /locus_tag="PK063_15765"
     CDS             15032..15823
                     /locus_tag="PK063_15765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HMZ98557.1"
                     /translation="MAYHRIAALVIRHLYLYRRSLPRVMEIIYWPFLDLVVWGFITVY
                     LATFQGQMPAVVTFLLGALILWDVLFRSQQGITISFLEEIWARNLMNLFASPLTPSEF
                     LAATMVMSLFKVTAVSVVMSLCAWVFYGYNVFIIGLWLMPFIANLVLTGWIIGVFTTS
                     LIMRFGQEAEVLAWSMVFLFQPISCVFYPMDVLPAWLRGVAAINPAAHVFEGMRGLLA
                     THAAPLTNLGMASGLNLLYLGAVVFWFHHTFNVCKERGSLVRVGE"
     gene            15864..16538
                     /locus_tag="PK063_15770"
     CDS             15864..16538
                     /locus_tag="PK063_15770"
                     /inference="COORDINATES: protein motif:HMM:NF025024.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2OG-Fe(II) oxygenase family protein"
                     /protein_id="HMZ98558.1"
                     /translation="MKVVAGQVGQARSVAGLENFSFHKTPVLVIENFWSADERGQFRE
                     AMARANWNQLQEMSYVRQDFPNSGNWAKAEIAQPQGRLLLSRLELPCIQQYIESFPNI
                     TRRHMGFSYYSYGAGDCLLTHDDTDQGHPTSGRPAPRRRIALVSYFHEEWDCDWGGEL
                     MIYAPGGESKAGKPDLAITHCIAPKPGSLVMFTVPRFHRVCRVDQTAGDHKRLSIAGW
                     FMTEHA"
     gene            complement(16694..>17247)
                     /locus_tag="PK063_15775"
     CDS             complement(16694..>17247)
                     /locus_tag="PK063_15775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ98559.1"
                     /translation="VNHYLHAGHIQPCAEWPDLSQAPGNEVVRLRAVRAQTESGLIKD
                     RFDIRRPIDLEVEFDVLKPGQVFVPVFNLYNEEDVTVFIAHDRDPAWQRTPRPAGRYT
                     STARIPGNLLAEGMLTVSPLMMTEDPFRLHAHAPRALGFRVDDSADGDSARGDFHGRW
                     PGVIRPLLEWRTRFEPVRDGRSG"
BASE COUNT         3306 a         4688 c         5455 g         3798 t
ORIGIN      
        1 gggtgatcaa gaacggcagc ccgggcaccg gcatggtttc gttggtccct gcggcaatca
       61 ccgaagaaga agcctggacg atcatcaatt atgagcgcag cttctgcaag ggtggagacg
      121 aatagtcacg attctcggcc gataggctga atcggagggg cggcgagggt atcctcgccg
      181 ccccttttct tttgtatcgc gctgacgaat gtcggcgcaa tcccgtgtga gtcccgagta
      241 acgtgtgaca ggaaggaatg ccccgtctac ctcatcccgg ctttctgccg tgacggataa
      301 agggcgaaat gcaccgcatt ttacggttgg tcagagggga acgtcatcgt tggtttggtg
      361 agcacggtgt cgagaccctt ctccgatcca cgcagtgtcg ggaggatctg cggttgctgt
      421 tcctgtttga aggtactccg cgctgcgccc ggtactttgc gattgatgta agcggttacc
      481 tccgcaatcg tgacctcgcc attccgattg agatcggctt cgccccgaag acctcgcagg
      541 agatagtacg taaacaatcc gtgatgccac gtttcggatt ccaagctctt gccgaagccg
      601 gtcgtcgcaa tcatgtgcag taccgatcct gatgtcccga gccatttcgg agccgctgct
      661 ttcgtgcgcc cgtccgctcc attcttgagg actgtcccgt caaagacgaa gagcacttgc
      721 ttggctttca atcttcccag cgccgcttcc aattccttga gtggatacag gcgagtgggt
      781 gatcccatcg agccgtcata ggggatcagg aaggtatcgc cggcggcgtt caccatcgct
      841 tgccccgcaa agtagacgac caccagcgac tctttggtcg tttttgcagg aagccaatcg
      901 agcagggcct cttcgatgtc ggggcgaagg gcgctccagt cccgcaggag gcgaacgttg
      961 ttttgaggta aaccgccgag ggtctgaaaa taggccgcga ccgtctctgc atcgagcgag
     1021 gcatattttc gcgccgcgat gtcctgttcg cgataactgc tgagtccgat ggcaaggaga
     1081 tagtcgcctg gacgctgtgc tcctgacgta gcggcaggaa tgtgatccac gtcctcgagg
     1141 agcgcggctg tcggttgaaa ggagagcggt aatgtttgtg gtggagcggc tgcttgtcct
     1201 gaggcgttaa gcagcgcaac ctgtaactcc gcccgttgaa gcgacgggga ttgaggcatc
     1261 gtcgcaacaa attccagcga tttggaaccg gccgccggga tggtcccggt ggccagcgtt
     1321 gtggcaggga actgcgtaag gaccgtctgc gggcctgtca gtttgacggt actgtcctgc
     1381 accaactgcg tgcccgtatt gaccacgtcg actcgcacgc ggattcgttc accactttcg
     1441 atgatcagat tgccgttctc atccaacaac gtggctttga acgaaagcgg ctgaaccggc
     1501 gttgcagcag gagcggctgg aacggcggtc gccttcgagc ttggctcggt aggcgtggca
     1561 gtcgtggcag ccgcaggcgg tggtgtcgcc ggggccagga gcacccgtgc ctcttgcatg
     1621 aactgcgtgg ccagcatggt agacgtatcc tgcaacagtg gatcgacaat gtaatcgcag
     1681 cgctgttgcg tcagttcgag ttgcaaacgt tctttccggg tggcttggag cggccgctca
     1741 ccgagcggcg cgccggacgc atcgaaaaat tccgccaggg catccaggct gagttccgca
     1801 ggggcacgat catagagggc gtccgtttgc agcttgaagc gtggatccag catacgcacg
     1861 cgtatcgtca cgtcaggttt tcccccggcc gcctggcttc ccggaatcgt gacggtgcga
     1921 aacgtttgat gtgccgcctg gatcaatgtg tcttcgacgg ttggcccgat cgagaaggcg
     1981 tggatgcggc tgcagttatc gatgtactcc gtcttggctt tggagagaga cggatcgatc
     2041 tccatgtgaa cggtgagggg gacaggaggg cctagatctg gcaacgcttg acgggaaaat
     2101 cgcgatttga tggactcgca gccgacggaa gccagcaggg agagtagggc aattccaaca
     2161 aggactacgc ggtttgtctt caagcaggcc tcctcgacgg cagaataaga atgggaaacg
     2221 gtacaggaat gaggggggca ttgcaaccaa gcgctgggcc ggcttgcgac cctcaccggc
     2281 ctcgtttatc ctaccgccgc gcctcgccta aacggcgcat tgatcggcgc gggagtcgcg
     2341 ttgctccttg ctcctcagtc aggcaatgaa aaagacaaaa ggacgttgac gtatcgtggt
     2401 ggtgttaggt ttgtccaata tgcgagatgc cgcggccgcc ctcgttgctg acgggcggat
     2461 cgtggctgcc gcagaggaag aacgcttcgt ccgccaaaag cacgtgacgg ccctgccagt
     2521 gcatgcgatg cagtattgcc tgcgcgaagc cggaatggct ttgcgcgacg tcgacgccat
     2581 cgcggtgccc tggaagtatt ggcaggtggg gcggcgtctc aggcttgcgg tgacggcgat
     2641 gctgcgctcg acgcaactgt tccgtgtgaa ggggacacgg tcccttgagc gggcgagtca
     2701 agaatggaag gaactcttcc ggcttcagca ggaactatcc acgcgggttg aaccgggtgc
     2761 cggccggccg gtgtttctcg accaccatct ctgccatgca gccagctcat ttctcgtctc
     2821 gccatttgaa cgggcggcga ttctggtggt cgacggagca tcagaatcgg atacgacctt
     2881 gctggctacc ggtgaaggca atcagatcag cgtactggag cgcacgccgt tgcctcactc
     2941 gctggggcaa ttctatgcgg cgatgacggc gttcctgggg tttcgcccgg atcaggatga
     3001 atacatcgtg atgggtctcg cttcgtccgg cgagccgtcg ttcgccccca cgctgagtcg
     3061 cgagattttg cgagtgctcc ccgatggacg attcgaactg aatacccgcc tgctggattt
     3121 ccacctcgcc agggcgggcc atttcgtgcg ggaattcatc cggctgttcg gtcctccgcg
     3181 gcggccgcaa gacgagatca cgcagcgcca ccgcgatctt gcggccagcg cgcaattcgt
     3241 gttggaagaa accctgttgc atctggggcg tcgtctgcgt tcgctcactc aggcgacatc
     3301 actttgcctc gcaggtgggg tagcctacaa ctgtgtcgcc aacggtcgcc tgcgggccga
     3361 actcgggttt gaccaggtgt acgtgccgcc ggctgccgga gattccgggg cggcgctcgg
     3421 cgcggccctc tggtggacgg cgcggcgagg agcggcgacg tcgaagaccg ttatgccgga
     3481 tgcctatctc ggtccgcagt atgacgaatc cgcctgccgt gccgccttgt cgaagacagg
     3541 actggttgcc gaacatctgg cagatgaccg attgtacgaa cgggtggcct cggagttggc
     3601 ccatgggcga ttggtgttct ggtatcaagg gcggatggag tggggcccgc gcgcattagg
     3661 aaatcgcagt ttgctggcgg atcctcgacg ggaagacatg cgtgaattga tcaatagcaa
     3721 ggtgaaatgt cgcgaggctt ttcgaccatt cgcaccctcc gtccttgccg aacacgcgga
     3781 ggagtttttc catgtgcctg ccccctcggc cttcatgcag tttacggttc gagtgaaagc
     3841 atcagcgaag gggctcctgc cggccgtgac gcatgtcgat ggtaccgctc gtgtgcaaac
     3901 cgtgacgcgt gaagccaatc cccgcttcta tgatctgctg gcgacctttg gcagattgac
     3961 gggtgtgccc gtgctgctga acacgtcgtt caatgtgcag gaaccgattg tgtgcagtcc
     4021 cgacgaagca gtgcgttgtt ttcagcgtac ccaggtggac tggttggttc tcggcaatct
     4081 tctggtggga cggccgtcac cgatgccgcc gcagcatcat gaaggctgag ccggttcgcg
     4141 gttcctttcc tcttcctgcc ctcatgctca tactggatgt gttgctgggc gcgtttgtct
     4201 tgaatctggt gctccaaccc ttagtggaac cggatctagg atggcatctc cgggccggac
     4261 tggatttgat cgcgcaaggg tggcgtttgc cggataccga cccctattcc catacgatgc
     4321 cggattggca ttgggtggag catgcctggt tgaccgatgg gctgttggga ttaatctatc
     4381 ggatgcttga accatctggc ggattggggc tgattgcgtt ttttggagga gtcacagcgc
     4441 tggcctggtg gatcgcggca ggagtagctt ccgtccatcg cacgtgccgg ttagcggcga
     4501 tggtcgcgag cctctgggtg gccttaccct ttctcggcgc gcgcacgcag ttgatcagcc
     4561 tccttggcgt ggcagttgtg ctcacgatat ggaatcgcat gcagcgggga cagccgcaat
     4621 gggtctgggc tctgccgcct ctgtttctct tgtgggccaa tcttcacggc ggcttcacgg
     4681 cgggtctgtt tttaatcacc gtgttgttgt cgctctcatt cctcgtgaaa atctgcgtcg
     4741 agtggaaggt cgttcaggca ccgcgtgatg aaccggtgct cagctgggat gttatccggc
     4801 tgtgtgcttt cgccattctt gtctcttttg ctgtgacctg cctgaatccc tatggctggc
     4861 gtctctatgt ggagatttac gaatcattga cggatcgctt catgatcgac accctgcggg
     4921 agtggcagcc ggtgtcgttt cacgggtggg ccggacgggc ctatgggttc tatctccttg
     4981 gatttatcgg gttgatggcc ggatggtatc ggcgagtgga gccggtgcgg tgggtcctgc
     5041 tggcgctgat gctgggattg tctttgctgc attggcggaa tgtcactctg tttttgatcg
     5101 tgagtctccc gttggcggca gagttaggtg cggctgcggc agattccttc ctgcgtcgcg
     5161 ttcctgtgct gcaagcccac gctgccggca ctgtccttgt ggtatccatt atggcggcga
     5221 cggcgctgta tgccttggga actgagcacc tggagcatgt gtggcaatca ggccgtactc
     5281 ccgatcggta ttttgagcgc acggagtatc ccatcgaagc ggtgcggtgg attcgggctc
     5341 accgggatga aacggggacg aggctctata acgactatag ctacggcggg tttctgctat
     5401 ggcaacttcc aggcgagcga atcttcatcg acggacgcat gcctgcctgg cggatcaagg
     5461 acagatggat ctttcacgat tacgttgaac tcaatcgcga agattcgccg caattggcct
     5521 tgctggatcg atacggggtg gattgggcga tgatcccgcg tggcagcgcg ttggcagtgg
     5581 ctctggaggc gcatcctgcc tggaagaatg tttatgccga tgccaaggtg gtgattgtgc
     5641 gccggcagtc gtgaccgcag ggtgcgtcgt ttaggaatgc gtcggttcga ctgtaacgag
     5701 gtccggttcg acggcgctgg atgccgggcg tgattggggc tggtaaaggc cttgggcctc
     5761 gcgcttacgg atggccagaa gttcccgcag catcaaggag ccgtcgcgcc aagggcgaac
     5821 tttcgagccc ggctgatcgg tccagttgat agggacttcc gcgatgcggt agtgccgttg
     5881 gcgggcgatg tgcagtaatt ccaggtcgaa tgcgtagccg tcgacacagg atacggcaaa
     5941 caaatcctga gccaccgatt gtcggaacaa cttaaacccg cattgcgtgt cggcaatatg
     6001 cggcacgccc agccgttgca ccacatggtt gaagaggccc cccagcaggc tccggtgcca
     6061 tcgggcatga accgtaaagg ccgggtcgtg ggaggccagg gcccgtgatc cgatcgcaag
     6121 gtcagccccg gccgcgagcg ccgcttccaa tcgtccgagt tcttcaatgg gagtggctcc
     6181 atccgcgtcg gcaaatagct ggatggttcc gcgcgcagcc tgcatgcccc gtcgaaccgc
     6241 cgcgcctttg cccatgttgc aggtcaattg aatcagccgc agatgaggac agtggtgtgc
     6301 cgccatcctg acggcgtgag cggtgttgtc ttgactcccg tcgtccacca ccagaatttc
     6361 atagaattgc ccgcgctggt ccagatgggc aatcacacgt tgcaaaaaca gcgggagccg
     6421 gcgcgcctca ttgtaggcgg gaatgatgac tgaaagggat ggtgtctggg tcgagcacag
     6481 agtcacgttg gaacgccccc ggtgggagtg tgacgcgacc gcttcgtccg gcgacgaagg
     6541 gtgcaccacg gtagctgagc catgatcgaa atgcaagcca tggttggcac atcttgacag
     6601 aggcagagcg cgggagtgat cgtatctcag atacggcggt atccttggcg tcgatccggt
     6661 ccggaggatg tcatgaggcg cagcgcgaac tgcttggcgt cgctcgtcgg catggtgatc
     6721 gtgacgagtt gtgccgtcgc cagtccgccc agtcgcctcg ctcagtatgt cggatccgtc
     6781 gtgccggaag aggcggcgac ggcgacgctt cccacttcgc gtccgctcca tgccgcgctg
     6841 gtcgtggtcg cggatcagtc ggctccggat tcagcgcccg ttttgccaga cgaagccctg
     6901 gcgcgggtgg gagcgctcct cacgggggag atcaaccgtg ggtatcccgt cgctgttgac
     6961 cgagtcgtca agcttgatgg gatgtcaccc gggggaacag cgccgagctg gcctgaggtc
     7021 gccaggcagc aaggggttca gtatctgctg gtgacggttc tgtcgagcac cgagcaggaa
     7081 tatccgattt ctctcttttt ggggtggacg acccaccaac agcctggatt tcggcgcgat
     7141 aactggtctc tcgccgaagc ggcgttgatc gacggatcga ccgggaggac ggtgctgcag
     7201 gcggaaggac gagccatggc cacgttggac cgcccgacgg cgccgggaat ttcgcaatgg
     7261 tatcccgtca tttatctgcg gccgcaagac ccggagcgac gcatttggcc gcccacctat
     7321 gaaggggctc cgctcacact ccgtctggtc tcgatggaac aggcggcgaa gcggttggcc
     7381 ggcaatctgc agcgagcctg ggtagaacag cgggatcttg aactcgctgc gcgctaaggc
     7441 tctgagccgt cggtcggagg tgacgcaggc tcggtccaga cgatgatggc atcaggttcg
     7501 gagccgcgtt ttcctctttg aaggcgattc tgtgattagt gtagaatgaa acgttcaacg
     7561 ttggcgcgga ggatggtccc tcaatctcag gtttccagag gagtacacat ggtgtatcga
     7621 cacgagcgca ggagagtgcg gtccgtactc gcagtaaccg cgatggttgc tgccacattc
     7681 ttatccggtg gattaccgcc ccgggccggt caggccgagg ctgctggtgt tcccccggca
     7741 ttcgctcaag ggttttctga aatcgtaaaa gctgtcaccc ctgcggtggt gaacattgcg
     7801 gtgaccggtg gtggcgaggg acgccgggaa ggtcgtcgtc agcttccccc aggcggtccc
     7861 ttcggcggtc cgcctcctgg tcccggtggt cctggtgatg aacctcctgg catggagcct
     7921 cccggtggcc ctccgggcgg tggtccccat cgtcccgagc aaagcgcagg gtccggcgtg
     7981 atcctcgatc cgaacgggta tatcgtgacc aataaccacg tggtcgaagg cgccacccaa
     8041 atcacggtga ccctctcgga tcgccgcgaa ttccccgcca aaattatcgg aaccgatccc
     8101 aagaccgatc tggcgattat caagatcgaa gccaaagatc tcagctcgat gaagtgggcg
     8161 gattacgatg agctgcaggt tggcgatgtg gttctggccg tgggtagtcc gttcgggctc
     8221 agttcaaccg tcaccctcgg cattatcagc gcgttgggtc gggggaacgt gggcatcgcc
     8281 gactacgaag actttattca aaccgatgcg gccatcaacc ccggcaattc gggcggtgcg
     8341 ctggtcaaca tgcaaggcaa gttgatcggc atcaatacgg ccatcttctc ccgcaccggc
     8401 ggatcggaag gcatcgggtt cgccattccc agcagcattg cgaccgatat cgtcgatagt
     8461 ttgacgaaga ccggcaaagt ggtgcgtgga tggatgggtg tggccattca ggaaattact
     8521 ccggccttgg ccaagtcctt caagttgcct gagcagcgca agggcgtctt gatcagtgac
     8581 gtgaacgaga atgggccgtc ccatacggca ggcatgcgcc gtggtgacgt ggtcatttcc
     8641 ttcaatggca aggaagtgca gagcgtcagc caattgcgca acctggtcgc gcgcatgggt
     8701 gtcggcaaag atgccgacat taagattttg cgcgaaggca aggagcaggt gttgaaggtg
     8761 aaggtggctg agcgtccgtc ggatgaggtg ttagcgaagc gtgagccggc tccctcggcg
     8821 gctcctgccg agacggtgaa gccaccggac aacgtcctgg cggccttgcg cgtccaattg
     8881 ctggatgcgg cgatgcagag ccagctgaac atcccggcca agactaccgg tgtcgtggtg
     8941 agttccgtcg aggcgggcag tgccgctgag tcggcgggat tgcagcgtgg cgacgtcatt
     9001 caggaagtca accacgaagt cgtgaagagc cttgaggatt accaaaaggc gtcagccaag
     9061 gtgaaaaagg acgaaatggt cgttcttctg ctgagtcggc agggaaacaa tctgttcgtt
     9121 gccgtcaatc cgaagtaaga catggatgag ggaacgatcc gtcgagtgag cggggaattt
     9181 ctcccgtact cactcgacgg agagtcctgc ctcaagtttg tgaacaggca tggctgacgg
     9241 gttcaagttt caagagtggc tgcaagacac agtctttaag ccgcttgaag ataaaaaaat
     9301 gccggtcatg gagcacttgg ttgagctcca ggtccggctg acccgtgcgg tcattgtgac
     9361 ggcgatcatt tttgtcggca ccttcttcta cgccgacacg ctggtgaagt ggatcagaat
     9421 cccgctccag aacatgttcg tgccggggtc cctttcctgg atccccacgg atcttcccac
     9481 cgtcccgttc gtctttctcg cgccggctga agccttatgg caaaacgtaa aggtcgcagg
     9541 tttgtttgcg ctggtgttgg gcactcctta catcctcgtt gagttctggc atttcgtggt
     9601 gccggggttg cacgcgcagg aacggagatt cgtcgggccc tttgtgatcc tcagcacgct
     9661 ggccttttat ctgggcctgt tgttttcgtt ctttttcgtc ctgccctttg ctttgaactt
     9721 tctcatctcg tatggcgtga atgccggatt tattccgcaa ctctcgattg cgcaatatgt
     9781 cggattcgcc ttatggttcc tgctggtctt cggtctcatc tttgaagtgc cgctggtgat
     9841 taccctgctg gctaagctag gctgggtgga tgctccattg ctgaaacgtt atcgcaagtg
     9901 ggccttcctg acggcgttta ttttcgccgc gattctcacc ccgacacccg atccgttcaa
     9961 ccagtgcctc atggcactgc ccatgtacat tttttatgaa gtcggcatcg tgagcgccgg
    10021 catcttcaac aaaaagaagg ccgacgcgcc ggcggaacca ctcgtgccgg cagtggtggc
    10081 ggcgggaccg gggctcgcga aagcgggacc aaccattccg tctggcggtg gagacgatga
    10141 gtatgtcggc gtgccgagcg gcggccggcg aggatgagca agaccggagt agagcaacag
    10201 ggcgaaagcg cgctttcgtc ttacgcagta tgatgttcgt tgtacgagga gttgaggaat
    10261 gccacgcgag ttaaatgtta tttcacagcc cggttccagc agcggcggag atgcctgcac
    10321 ttatatgtgg gcctgcgcca tttgcgacga aaatgagact tgtcaaaagg acaaggaagg
    10381 ccacagccgc tggttggtcg caaagcgcat ggaacggatc gaatataaag tgcttgtcat
    10441 gagtaataaa ggcggcgtgg gcaagagcac ctgcaccacg aaccttgctg tcagtcttgc
    10501 gctgaagggc tggcatgtcg gtatttgcga catggatatc catggcccca atattccgaa
    10561 gatggtcggg gcggagggac aaaagctgaa gatcagcact tcgggcggga tcatcccgtt
    10621 tcaggcctac aacatgaaga ttgcctcgat gtccttcctg ttgcagaact ctgacgatcc
    10681 catcatctgg cgcgatgcgt ataaatatga attcatcaac cagttgctgg gaggcgtgga
    10741 gtggcaggat ctgaatttcc tgctgatcga tctgcctcct ggaacgggca atgagtccgt
    10801 gacgaccatc gatctcctcg gtggggtcag cggagcggtc attattacga cacctcaaga
    10861 agtggcgttg ctcgattccc ggaaatccgt gacgttctgc aaggacagcg aagtgccgat
    10921 tatcggcatc gtggagaaca tgagcgggtt ggaatgcccc cactgccaca aggaagtgaa
    10981 tgtcttccgc aagggcggag gtgaggcctc ggccgcggat atgggtgttc cgttcttggg
    11041 acggattccg ctggatcccg acgtggtgac gcaaagtgat gcgggcgagc ccttcgcact
    11101 gttcaactcc gatgcggcaa cggctcaggc ctatcacgat atcgccaatc aggtggaagc
    11161 tttctgcaag aaaagcgggt cgctcataaa gccggcgccg cgacagcaac attgacggga
    11221 cggtgacctg tgaaatctgc cgatgcgaca gtcggattga cgccgcttca tgaagcccag
    11281 cgcattgtgc tggacgccgc ggctccctta gggctcgaga aggtctccat tatggacacc
    11341 ctgggccggg tgctcggcga agacatcatc gctacgcgct cgaatccgcc gtgggacaat
    11401 tccgcgatgg acgggtttgc cgtacgcgct gaggacattg cgcaggaaca cgcgatttct
    11461 aagcctgtca cgctaaccgt cattgaggat gtgccggcag ggaagatgcc caccaagtct
    11521 gtgggaaagg ggcaagcgat cagaatcatg acgggcgccc ctattcccgc cggggctgat
    11581 accgtcatca aggtcgagga tactgaacat acgcccgatt ccgtgcgtgt gttcaaagcg
    11641 gaaccgcgcg gctcaaacat ccggccgcag ggtgaggatg tgcaaaaggg cgactgcatc
    11701 attccgaagg gcacccagat tcgatccggc gaagcgggta tgttggctat tctcgcgaag
    11761 tcctttgtgc tggtctatca gcgtccgcgc gtcgccatct tgtcgacggg cgatgaactc
    11821 gccgatcttg acgaacgctt cagcgaagaa aaaatcatca attcgaacag ttacggtatt
    11881 gctgcggcgg tgcaagaagc cggcggcgtg ccgatcctgc tgggcattgc tcgggatacg
    11941 cctgcggcct taacggaaaa aatttcccac ggattaaacg cggacattct cgtgctatca
    12001 ggcggcgtgt cgatggggga ttacgacttc acgaaagcag tattccggga cctgggtgcc
    12061 gagatgaatt tctggaagtt ggccatccgg ccaggccagc cgctcgcctt cggcaaaatt
    12121 cagggaaagc tggcgttcgg actgccggga aacccggtct cttcgatggt gacctttgag
    12181 caactggttc gtccggccat gttgaaactg tccggcgcgc gaagctatgg acgtccgttg
    12241 ctcgaggcgg tctttcagga gaagttttcc aagcgaaccg atcggcggca ttttctgcgc
    12301 ggggtgttgt ggcgggaaga tggagtattc aaggtcagga cgaccggcga tcagggctcg
    12361 ggcattttga cctccatggt caaagcgaac tgtttgatcg atattccggt cgaagtagag
    12421 cgcctcaatc ccggtgatcc ggtaaccgtg cagcttctca gcgggtcggt atggctggac
    12481 caggccgctc cggctgcttc tgccgctcac cgcccctcct gctgctgacg ccgcgaaagg
    12541 aacgttgtca tgtccgtgcc cattctgtct tttgtcggcc ggtccaatag cggcaagacc
    12601 acgttgatcg aacgcgtgat tcccgagctt gtgcgtgccg gctataaggt ggcgacggtc
    12661 aaacatgccg gtcacgggtt cgatttggat accgagggaa aggacagctg gcggcacaag
    12721 caagccggtg cgagcagtgt cgtgattatt tccaagagca gtctggccat gttcgccgat
    12781 gtctcggacc atatgaacgt cgaggacgtt cgtgagcgat acctcgatcc ctcgtatgat
    12841 ctgatcctgg ccgaaggatg gcggagcgaa ggctatccga agatcgtcgt cgtgcgcgac
    12901 cagatcggtg aggtgccggt ttcgcaagac ggcctcctag cggtcgtgtc caacaaaccc
    12961 gtcgaaacct ccgtcccgct gctggatcct gatgatgtgg cggcggtggc ggcattgatc
    13021 atccggcatt tccccaaatc ccaacgggat gatgcgtagt actcccgcca ttgtgttcgg
    13081 ggcgattctg gccggcgcag tggctttcgg gggagttgcg gttccgctga cgaaccatcc
    13141 gaaattctgc gccagctgcc ataccatcca acccgcctat gagggctggt tgcaatcatc
    13201 ccataaggaa gtggaatgcg tggcctgtca tgtcaggccc ggtgtggtcg gctggttgca
    13261 tgataaggcc tggcatggga cgagggacgt ggcgatctat ctgttcggca aaccgacgga
    13321 gcctcacaat ctgcaagctc aggtggattc cgccgtctgc ctcggctgcc accgcaatat
    13381 cctgcgggtg tcggaaatcg cgcctcgtga tttgccgtct cccgtcaagg atgtggggct
    13441 gatcatgagc catcggaaac atatggcggc gtttgatcag cgtgcgcaag gcgaagggtg
    13501 taccacctgc cacgcggcag tggtgcatga acggccgatc aaaggatatc caatcgtcat
    13561 tccccgaggc catgtgtcag ctgatagccg tccgtggaat tccacacatc ctgagggctc
    13621 ggtgttgcac aaacgggcac aggcggattg ctttcgatgc cacgataaca aaaccgaata
    13681 tgaaggccgg gtgctgagcc gaaagtgcga aacgtgccat ctgcctgaaa aactctcgga
    13741 attcctgtcg ttttagccca cggaaccagc tgcccatgtc atcgccggtg gtcgaagtac
    13801 gtaatctcag taaacgattc ggtggattca ccgcggtcga cgggatttct ttcgagatcg
    13861 gccgagggga aatcctcggc ttattgggac ccaatggcgc cggcaaaacg acgacgtttc
    13921 aaatgatgtt agggttagtc acgcccacag ccggctcgat ccgcatgttc ggtctcgact
    13981 tgcagtcgaa tcgggaaacg attcttcagc aggtcaattt ttcctccacc tacatttcat
    14041 tgccgttctc cctgacggtt gaggaaaatc ttcgagtcgt cgcccgattg tacggcatgt
    14101 ccgatatcgc ggcccgtgtg gatgatatgg taaagaaact ggagatgggc gactggcggc
    14161 acaagctgac gcgcaaactg tcgtcagggc agatgacgcg tttgacgttg gcgaaagctc
    14221 tcctgacgga acccaaagtg ctgtttttgg atgaaccgac ggcgagtctg gatccggata
    14281 tcgcgcacaa gattcgcgcg atcctgttgg aggaacggca ggcgaccgga ctcagtattc
    14341 tttacacctc gcataatatg cgggaaatgg aagagatgtc ggatcgcatt atttttctgc
    14401 agcggggaaa gattgtggcc gaaggcaccg ccaaagacat cgtggctcga tttggtcagg
    14461 cggacctgga ggatgtgttt cttaaactcg cgcgcgagta gcaggcccgc gcgggatcgt
    14521 gtgatgtgca aggggagcag gcagcgccat ggttgatgca ggaatatcgt ttactgtggg
    14581 ggtactcatc ggcggcctga gcctcatggt gggatggggc ttgttgtggt tcgtcgtggg
    14641 cgggatcggc ttggcacggc agaccagcgg atggccgatt tttatcagca gtatcagcag
    14701 caccgcgatt gcgggcggcg tcatggctgt ggtgttctgg gctgtcgatg ccgcacgact
    14761 gagcagcccg gcgttgcacg tcggtctggc agggattcca ctggccttgc ttgcggcgtc
    14821 agcctttcgc ttggaagacg gccggcgaat tggtccggcg tttgtgcaag ggagccgctt
    14881 gatgatgcag gaactactcg gcgggcatca ggaagagggc ggatgcggcc attgtcatga
    14941 acagccggtt gaagagcatc cctgtcacca gaagccgtgc ttcgaacagt cctgccacga
    15001 gaagccttgc gaagggaagc tgtagccggc gatggcctac caccgtattg cggctttggt
    15061 catccgtcac ctgtatctct accggcgcag cctgccgcgg gtgatggaga tcatctattg
    15121 gccgtttctc gatctggtgg tgtggggctt catcacggtc tatctggcga cgttccaagg
    15181 gcagatgccg gcggtcgtga cgtttctgct cggtgcgctg attctctggg acgtgttgtt
    15241 tcgatcacag cagggcatta cgatttcctt tcttgaggaa atttgggcgc gcaacctgat
    15301 gaatctgttc gccagtccgc tgacgccctc cgaatttctc gcggctacga tggtcatgag
    15361 cctcttcaag gtcactgccg tgtcggtggt catgtccctg tgcgcctggg tgttttacgg
    15421 ctacaatgtt tttatcatcg gcctgtggct catgccgttc attgccaatc tcgtgctaac
    15481 gggatggatc atcggtgtgt tcacgacgtc gctgatcatg cggttcggac aggaggcgga
    15541 ggtgctcgcc tggagcatgg tctttttgtt tcagccgatt tcctgcgtgt tctatcccat
    15601 ggatgtcctg ccggcctggc tgcgaggcgt ggctgcgatc aatccggcgg cacatgtgtt
    15661 cgaaggtatg cgaggacttc ttgcgaccca tgcggctccg ttgaccaacc tcggaatggc
    15721 gagtggtttg aatctgctgt atctcggcgc ggtggtcttc tggtttcatc atacgttcaa
    15781 tgtctgtaaa gagcggggat cgttggtccg ggttggcgaa taattgatcg cgttcggcgt
    15841 gcgcgggttc gaggaggaga cgcatgaagg ttgtagcagg acaagtcgga caagcacggt
    15901 cagtagccgg gctggagaat ttttccttcc acaagacgcc ggtcctggtc atcgagaact
    15961 tctggtcggc cgacgaacga ggccagtttc gagaagcgat ggcgcgggcc aattggaatc
    16021 aactgcaaga aatgtcgtac gtccggcaag acttcccgaa ttccgggaac tgggcgaagg
    16081 ctgaaatcgc ccagccgcaa ggacggctgc tcttgagccg attggaattg ccctgcattc
    16141 agcagtatat cgaatcattt cccaacatca cccgccgtca tatggggttc agctactatt
    16201 cctatggagc cggtgattgt ttgttgacgc atgacgacac ggatcagggc catccaacga
    16261 gcggcaggcc tgcgcctcgt cgacgcatcg cactcgtcag ctactttcac gaggaatggg
    16321 attgtgactg gggcggggag ctgatgattt atgcgcctgg aggtgagtca aaggccggga
    16381 aaccggattt ggccatcaca cattgcatcg caccaaaacc gggatcgttg gtcatgttca
    16441 ccgtgcctcg ttttcatcgc gtgtgccggg tggatcaaac agccggggac cacaagcgcc
    16501 tctcgatcgc tggatggttt atgaccgaac atgcctagca ggatgttgaa aacgtctgcc
    16561 agtctcgttc tcgcaagaca ctgcaccctc accgtctcgg cggcgttcac aaacgtggtg
    16621 cgcggtattc agcggaacgg cctgtttgac cattccacgg gttacacacc aacatgccgc
    16681 ttcagtacga ccatcaacct gaccgcccat ctcgcaccgg ttcaaaccgc gttcgccact
    16741 ccagcagagg tctgatcacg cccggccatc gtccgtgaaa gtcacctcgc gccgaatctc
    16801 catcagcact gtcatccacc cggaacccga gagcccgcgg cgcatgcgca tgcaggcgaa
    16861 atggatcctc cgtcatcatg agggggctta cggtcaacat tccctcggcg agtaagttgc
    16921 ccggaatcct cgcggtggag gtataccggc cggcgggacg gggggttcgt tgccatgccg
    16981 gatcccgatc gtgcgcgatg aacacggtca cgtcttcttc gttgtagaga ttaaagaccg
    17041 gaacgaagac ttgccccggt ttaaggacat cgaattccac ctcgagatca atcggccgcc
    17101 ggatatcgaa gcgatctttg atcaaccctg attctgtttg ggcccgcact gcccgcagac
    17161 ggacaacctc attgcccggg gcttgggaca gatccggcca ttcggcacag ggctggatgt
    17221 gcccggcatg cagatagtga ttcacca
//
LOCUS       DAOQPD010000086        17056 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1686_length_17056_cov_22.966414, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000086 DAOQPD010000000
VERSION     DAOQPD010000086.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 17056)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 17056)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17056
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1686_length_17056_cov_22.966414"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(150..566)
                     /locus_tag="PK063_15780"
     CDS             complement(150..566)
                     /locus_tag="PK063_15780"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98560.1"
                     /translation="MMYSRSHGAVVLSLSLLLLSACATEETMTTGGSTPAASASASMK
                     TTAQAYDSLQSCLDRIPSGGTAGNRMIAEESCRRDETFRQSIAGNAATKSGNRYAAGA
                     AGDSLEACMARIPKDGSVGQRMLAEESCKRDQANQR"
     gene            complement(646..2016)
                     /locus_tag="PK063_15785"
     CDS             complement(646..2016)
                     /locus_tag="PK063_15785"
                     /inference="COORDINATES: protein motif:HMM:NF025598.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4340 domain-containing protein"
                     /protein_id="HMZ98561.1"
                     /translation="MARYWPTVLLAGVLAGLGLYLYFIELPEQRAELVTATQAKQILP
                     FEQAQISALRVRSHSGEVVLSQTPGHPWGITAPIQTDADQRQVQALLRALVTGKVSRL
                     VETHPVSLTPFGLDHPSTVVTVTAGDREETLSIGDAGPLSSTLYVLRASDEAVLLTDL
                     APKDFLNRTLLSFRRKELLQFNQQETEQLRLTYPTTEMVLYGIEEKPKKKWKIRYPIE
                     AEADRTEVQALLFRLEDLKALAIVDPGPEREKLAPLLTKPKVKVTVHAAGTDQVVRLF
                     QPDPASGEAYAQTAQDGPIYKISPSVIKELTKDLFALQDKRLLGAETGDIALLSIKTR
                     DEQYTLVHDRDGWMLEDQPNEKLRQDVADLLVSRIVNLPAEERILKQAGPLAPYGLVA
                     PVAEFIATGKNGRVAGRLALGNQSGGLVYAIGQRIPGVFQVRPDLLTQIPSRLALLAS
                     GPATPP"
     gene            complement(2020..3549)
                     /locus_tag="PK063_15790"
     CDS             complement(2020..3549)
                     /locus_tag="PK063_15790"
                     /inference="COORDINATES: protein motif:HMM:NF021351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gldg family protein"
                     /protein_id="HMZ98562.1"
                     /translation="MEMTRNPLPIGAIGTGLAIAGVIAYSLVPDKLWLVTLLEGLALA
                     CFIWAFATHFDQVKRFSSQRSTRMGANSAMMVALFLAILAILNFLAARHSIRWDFSEN
                     QNYTLAPETYRVLRNLTRDVNVTVFTREKDPGYQGYKERFDSYRQASPKLTVQFIDPE
                     RQPKVAQNYGVTRTDVAIFESGPQSVRITSPAEVEITGALVRVSKDSKKRVVFLEGHG
                     ERSLEDKDRGGMALTKEVLEKQGYEIGTVTLLQETAVPSNTDVLVIAGPRRAITKEEQ
                     DRIQTYVAQGGHLLLLLDPDTQASMDTLLKIWGLELGAGVLVDLQDRLAQGDLTALLV
                     RTFTDHEITHELTAAVLFPLARHLTFHEEQAKDWDYVPLARTSPRSWAETDMKGRVVS
                     YDEKEDVQGPLALAAALTPKQAPEEGKPRPAVVVVGNSAFASNGFINFVGNSDFFQRT
                     VGWLSEERDLISLTPKDPAVRPFTPNPLQERILLYVQVIFLPAMTVLCGLLVWRKRRR
                     L"
     gene            complement(3540..4310)
                     /locus_tag="PK063_15795"
     CDS             complement(3540..4310)
                     /locus_tag="PK063_15795"
                     /inference="COORDINATES: protein motif:HMM:NF024091.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HMZ98563.1"
                     /translation="MPPVQAIIRKELRSYFVSPIVYVVGGVFLLTFGFLAYLYIVFTG
                     AQAIQLMQMQGGTAQINLNDLVFRNLFASMRFVLLLILPILTMRLLAEERKLRTFEFL
                     MTAPIRVSEIIVGKFISVYLVFMGMLLLTTLVPLTLALFSDFDWYPVFTGYLGLLLLG
                     GFFLAVGLFASSVTENQIVAAFTSFGLLLMCWLLAGLGSLLGDTPVGQVVSYLSFMEH
                     YDHLVRGLIDTKDLMYYVSGTVLMLFLAHRIVDASRWK"
     gene            complement(4314..5282)
                     /locus_tag="PK063_15800"
     CDS             complement(4314..5282)
                     /locus_tag="PK063_15800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ98564.1"
                     /translation="MIEVCNITKRYGHLTAIDRVTFRVEKGEVLAFLGPNGAGKTTTM
                     RILTSFIPATEGTAHVAGFDCAEQPDEVKKRIGYLPETPPVYQELTVAEYLGFVGKLR
                     GLSGTGLTQALERVTERLSLGTVRQRLIANLSRGYRQRVGLAQALIHDPPVLILDEPT
                     VGLDPKQIIEIRELIKSLAGSHSVILSTHILPEATAVCQRVVIINGGRIVAEDTPDQL
                     SARLRKSEKISVTLKAPPVNLAERFREVPGIEHVLTTADPHTVLIECALGRDIREDVA
                     RFAVGQNWGLLEMKPVSMTLEDVFLKLTQREDEPPKSNDTTPGEHH"
     gene            5537..5902
                     /locus_tag="PK063_15805"
     CDS             5537..5902
                     /locus_tag="PK063_15805"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98565.1"
                     /translation="MNQARPSLLGVLVIGAALCVALAGLGSFLTSVYAASNTVHEIKG
                     TVENVHAHEDPPVIVVKGQHGSSEAIVVGAVVKQGATIMRGKKRITLDQIHAGDKVTL
                     KYVKTRDGLTVRSIALHRN"
     gene            5959..6615
                     /locus_tag="PK063_15810"
     CDS             5959..6615
                     /locus_tag="PK063_15810"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98566.1"
                     /translation="MIRQHVVRGMSAPVAVGLLLLMGCSGKGDIIPMNLTPKAKEMTN
                     ASSAVKPMAGPKVVVIPFEDARADHAKVGSRSSMWGGETDFHVSSGSAGEETGQALAD
                     YLKRKGWLVQYQKAAPAESENGPNIVLSGKILDLTVDAKRGFLMTDIEARSKLVIQAN
                     NREDGSSIVRTDAHSGSHDNVFWFDPQDGEELLGEVLEKNFERFVLNTKLEDRSIRFR
                     "
     gene            6955..7614
                     /locus_tag="PK063_15815"
     CDS             6955..7614
                     /locus_tag="PK063_15815"
                     /inference="COORDINATES: protein motif:HMM:TIGR00413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septal ring lytic transglycosylase RlpA family
                     protein"
                     /protein_id="HMZ98567.1"
                     /translation="MVRNFWNRSRCKTGSALAPLVACLLLSACSALPKGDLPLDLGIK
                     DRGVASWYGKEFHGKLAANGEVFDMTAYTAAHRKLPLGSLVRVVNLANGKSVQVRIND
                     RGPYVSGRMLDLSQAAARELGMLEAGTSPVQIEVIGNHRPVAPIPSSLIASVAGMLLN
                     TDTRVMKRHTRQEEGVEVPVVPLRMMPQEALYVRRERRIGSMLAADHSAHNTVPGLIV
                     S"
     gene            7746..7946
                     /locus_tag="PK063_15820"
     CDS             7746..7946
                     /locus_tag="PK063_15820"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98568.1"
                     /translation="MAKKPTGESDEVRLKKKIAASTKDESKSGVPAVRSLRKRLKRVQ
                     RKRRALVLRKKHAAGKQAEAKS"
     gene            8010..>8832
                     /locus_tag="PK063_15825"
     CDS             8010..>8832
                     /locus_tag="PK063_15825"
                     /inference="COORDINATES: protein motif:HMM:NF025030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HMZ98569.1"
                     /translation="MEHTGEKKDQAQAVSPVGPVEDEALTDQVSDQLAASLDSSVGEQ
                     ELIEPMQEVVLEEEKVKDEIDIQIDLLKDPDWVVRREAAITLGEMGDERCVEPLAAAL
                     RDGDWQVREVAIEGIGQIGSPAVDVLLKLLRDWDVRKSAIMALGKIRDERVLEPLMQQ
                     LRNDEFMEDATDALVNLGEPALPGLIKALKDKEELVRKQAVIALGRIKSPEAIDPLIE
                     MLQNKDWFTRLTAAAALEAIGDERGREAIKPLLKDTDMVVKMRVERILAKWKKQPA"
     assembly_gap    8833..8932
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(9106..10440)
                     /locus_tag="PK063_15830"
     CDS             complement(9106..10440)
                     /locus_tag="PK063_15830"
                     /inference="COORDINATES: protein motif:HMM:NF025030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HMZ98570.1"
                     /translation="MVWISPLPVGAATSTPKTSPSPLERDAMTFYRAAEYSRVIDLIQ
                     HPPTGQEPSLEAIRYAILSYVKMGKPEEAWKLYPKLTAGDRPDDPALLREIARAFIVS
                     RVRDSQEHIRIAAYTALAEMGEADTLPLLEDGLLDSSALVRARAAEAIGRSGLAGRSA
                     ALKRALRDEAPGVRIAAINALSDAKVSGITDQLTEIARVDEGPESIFAFAGLYKLGRT
                     DVLTDISSAVTLPDPEVRMAALGVLGRLKRPASLSILSQAVYDPHPAVRAFAAGALGE
                     FGSIEGIAPLTHALGDEDPRVRSVAASSLGRLGVSESRSVVQPLLRDSDEHVRISAVE
                     SLLRLGDTGVILNAAALARHPDPSIRGDTAHALALATTANALPILENLLRDQQPLPRL
                     MAARALGKSPLKSLIPAAKIGLQDSDAAVRITSAGSLLRILSRKDKVSTRKG"
     gene            complement(10512..12671)
                     /gene="glgP"
                     /locus_tag="PK063_15835"
     CDS             complement(10512..12671)
                     /gene="glgP"
                     /locus_tag="PK063_15835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucan family phosphorylase"
                     /protein_id="HMZ98571.1"
                     /translation="MQAPDHIQPPQDMVPQSLHRLGELARNLWWSWNQPARQLFESID
                     PTLWFLTHHNPVQLLAGVKPERFATLASDPTFARQYSAVLRSFDEYMSSKNTWAATEF
                     PALQNSPIAYFSAEFGLHISIPIYSGGLGILAGDHCKEASDLGIPLVGIGFMYPQGYF
                     KQRINPEGWQEATYVPFNRYDSPIHQALTPAGVPCTIKVQIGHRQVTVLVWQVRNGRM
                     SLYLIDTDVPENTPEDRALSARLYGGDQETRLCQEFLLGIGGVRVLRALGITPAVWHC
                     NEGHSAFLTLERIREFVSTGHSHAEASELVRQSTVFTTHTPVPAGHDIFPFHLMDRYF
                     HNYWGQLGLSREEFLRLGETPESAGHGFNMTALAMRLSAHVNGVSREHGRVSRQMWQH
                     LWPGLAQDLVPIRSLTNGIHAPTWISPESNSLYAKYLSPDWAERIDDPTIWQRVTDLP
                     DDALWAVRQTTRRKLMRFIRERARDGWIRGHLQPMQAIARGTLLDPEALTIGFARRFA
                     TYKRATLLFRDLERLKQLLHNRWRPVQIVFAGKAHPADEPGRYFIHEVLNFCNDHKLG
                     GHIAFLEDYDMHMAKYLVQGVDVWLNTPRAPLEASGTSGQKAALNGVINLSVLDGWWQ
                     EGYNGANGWGIQPLPEGSDTQAQDAHDAEQLFRLLEQEVVPLFYQRDLDGIPRGWLHI
                     VKESIKTVAPRFCTKRMVKEYMRQLYAPATARTPNKW"
     gene            complement(12741..13577)
                     /locus_tag="PK063_15840"
     CDS             complement(12741..13577)
                     /locus_tag="PK063_15840"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98572.1"
                     /translation="MTTKSHSFAQQMRTVAELMLAVSGESVSVIKRAAPEQALKLKRQ
                     DEWGIYLEFLRAMFNLTDRVSALHIPLREQPQFMDELTDTVIDQLKKVLEPAFGAGDD
                     QMEIVMTIGAAVSESRQTYERYRFLVTEESPAKNDLYRDFSDRVARAVGASGNPKVEA
                     AATLCIAAVIPALIGIFEGKTPAVPADATGNANPSAASSNPRGATGADIKLVSVMSSI
                     KGEEVETRWGLHPRFRQDLTQEEAKQLTATMNRVAKILGERYATVAFSDQWASWHKAG
                     HA"
     gene            13697..15781
                     /locus_tag="PK063_15845"
     CDS             13697..15781
                     /locus_tag="PK063_15845"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HMZ98573.1"
                     /translation="MLYSATAPVMSLTAQSDANMDRDTKPYILKRTPDQDVVRKFSLD
                     YAKELNPQQYAAVTAADGPALVIAGAGSGKTRTLVHRVAYLIDSGVDPSQILLLTFTR
                     KSAEEMLERVGALIGSRSQRVCGGTFHSVANMLLRRYGRVLGIEPSFTIMDRGDAEDL
                     IALLRAQLGLNEKDKRFPRKGTIAEIYSKCENTLRGLEEIVLDEFSHFADHLDALGKL
                     QRAYQLAKRQRQLLDYDDLLVLLRDLMTQDEASRQAISRQFRYILVDEYQDTNRLQAE
                     LIRKLAATHDNVMVVGDDSQSIYAFRGATFRNIMEFPSWFPGATIYKLEENYRSTQPI
                     LSLANEIIQEAPEKYTKHLFTRKLDGPLPALVEAAGENAQSRFVAQKILELREEGVPL
                     NEIAVLFRSSFHSFDLEIELSRCGLPFVKRGGIKFIEAAHVKDLLAHLRVVVNPHDAV
                     SWHRVLMLVEGVGPKKAQDLVAAMVRVTDPYQVLRDSSGRSGKGLKELAVVLENLSKS
                     DDLSPTEQVNRVYEYYLPILKDHHDDYPKRIRDLDHLHTIAESYPGLTEFLADLALAP
                     PDGSAVGVEAAGSDDEQVVLSTIHSAKGLEWQCVFLLWVVDGKFPSVFSFNTDEELEE
                     ERRLLYVAVTRAKRYLFLTYPINVYDRSSGMLLSKPSRFLDHVSPRLFESLALVEESH
                     GHDWGHDRDRYV"
     gene            15820..16767
                     /locus_tag="PK063_15850"
     CDS             15820..16767
                     /locus_tag="PK063_15850"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98574.1"
                     /translation="MSQFEAIMRCLRSYIDSMQGVAAVMVGGMLLVLLCSAPILAETP
                     AAQPDASRLWSGLVAEAKALRLPTQFLEQVPKHFVTFEFEDLHAFAAEYHPADHRMVL
                     DRSLSLNAAGRTLRPLGRLTHKELETLYHELFHVYMDFLEQEATPSEAHASLIAFARE
                     QQHCRYQQVLITPVLQKRALKEERFLSETESWEVLNETWAVFIGWAVWTQLEVDQKPR
                     RDSRGPAHTSGWIARLDQAEQDAALIGYYEPEDLEEKRMARKRFLAPEFRLSSPELLR
                     LMKDVLGSQPDVIRQATQVLQRSRPVASTRGACAASTKP"
     gene            complement(16753..>17056)
                     /locus_tag="PK063_15855"
     CDS             complement(16753..>17056)
                     /locus_tag="PK063_15855"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98575.1"
                     /translation="IRQQIYSLPPLSTWVPAREGPISKRKRATNQFKENKHQSVSFSG
                     SENEVSPTMHSSPAKRQGWIADKVRVDLASKAADFICDAFYCQGGMFYAGTILRLR"
BASE COUNT         3566 a         4460 c         5119 g         3811 t
ORIGIN      
        1 gtttaggaaa ccgctgctct atccaactga gctacggggg cgtcgtcgta cgatactgaa
       61 agacggtgag attgtctaca gcgaggcgcg cctccgaagc aggtgatcac ctccggaggc
      121 gcagcattca tcgaaatcgg aacgtcggat tatcgctggt tggcttgatc gcgcttgcag
      181 ctctcttcgg ccagcatgcg ctgacccact gagccgtctt tcgggatgcg agccatacag
      241 gcttccaagc tatcgccggc ggcaccggct gcgtagcggt ttccgctctt ggttgccgcg
      301 ttgcccgcga tggactggcg gaacgtctca tctcggcggc agctttcttc tgcaatcatg
      361 cgatttccag ccgtgcctcc ggatgggatg cggtccaggc aggactgcag cgagtcgtag
      421 gcctgggcgg tggttttcat cgacgcactc gccgaggcgg caggtgtcga tccaccggtc
      481 gtcatggttt cttccgtcgc gcaggcactg agcaaaagca gagataagga cagaacaacg
      541 gcaccgtggg aacgcgagta catcattgaa ggatcctcct tgatcaagag cgatgggcgc
      601 acagtagcat aatccccctc ttcctggaaa cactctcgtc gcggtttagg gcggtgttgc
      661 cgggccgctt gcgagcaggg ccaacctgga agggatttgg gtcagcaggt caggacggac
      721 ctggaatacg cctggtatcc gctggccaat ggcatacacg aggcctcctg attgattgcc
      781 cagggccaga cgtccggcca cacgaccgtt tttgccggtc gcgatgaatt cggccacggg
      841 ggcaacgagt ccatagggtg ccaatgggcc cgcttgcttg agaatacgtt cttccgcggg
      901 gagattcaca atacggctga cgagcagatc ggccacgtct tggcgcagtt tttcattcgg
      961 ctgatcttcc agcatccatc cgtctcggtc atgaaccagc gtgtattgtt cgtctcgcgt
     1021 tttaatggag agcagggcga tgtcgcccgt ttcggctccg agcagccgtt tgtcctgcag
     1081 ggcaaacagg tctttggtca actctttaat gacggaggga ctgattttat agatagggcc
     1141 atcctgagcg gtttgcgcgt aggcttcgcc gctagccggg tcgggctgaa agaggcgaac
     1201 gacctggtcg gttccggccg catgcacggt gactttcacc ttgggtttgg tcagtaacgg
     1261 ggcgagcttt tcccgttcgg gccccggatc cacgatggcc aaggctttga gatcttccag
     1321 gcgaaataga agcgcttgga cttccgtgcg atctgcttca gcctcaatgg ggtaacggat
     1381 cttccatttt ttcttcggtt tctcctcaat cccgtacagc accatttccg tggtcgggta
     1441 ggtgagacgg agttgctcag tctcctgttg attgaattgc agcaactctt tgcgccggaa
     1501 ggagagcagg gtccggttca gaaagtcttt cggcgccagg tcggtcagaa ggacagcctc
     1561 atctgacgct cgcagtacat agagggtgga cgagagcggg ccggcatccc cgatcgagag
     1621 ggtttcctcg cggtcgcctg cggtcacggt gacgacggtg gaggggtggt ccagaccgaa
     1681 cggcgtcaat gagaccgggt gagtttcaac cagacgcgag acttttcctg tgacgagcgc
     1741 ccgcagcagt gcctgaacct gacgctgatc ggcgtcggtt tgaatcggtg ccgtaatgcc
     1801 ccagggatgg ccaggcgtct gactgaggac cacttccccc gagtggctgc ggacccgtaa
     1861 ggcgctgatc tgagcttgct caaacggcag gatttgtttg gcctgggtcg cggtgacaag
     1921 ttcagcgcgc tgctcaggga gttcgataaa gtaaaggtac aggccaagcc ctgcaaggac
     1981 gcccgccagg agtactgtcg gccaatagcg cgccatgacc tacaagcgac gccgtttccg
     2041 ccagaccagc agaccgcaga gcacagtcat ggccggcaga aaaatcacct gcacgtagag
     2101 caggatccgc tcctggagag gatttggtgt aaatggtcga accgccgggt cctttggtgt
     2161 cagcgaaatc aagtcacgct cttcggagag ccatcccacc gtgcgttgaa agaagtcgct
     2221 gtttccgacg aagttgatga agccattgct ggcgaaggca gagttgccaa ccacgacgac
     2281 ggcgggacgg ggcttccctt cctcgggggc ttgtttgggc gtcaacgcag cggcgagcgc
     2341 caagggccct tgcacatctt ctttttcgtc atagctgacg acccgaccct tcatatctgt
     2401 ttctgcccag ctccgcggtg acgtgcgcgc caatggaacg tagtcccagt cctttgcctg
     2461 ctcttcatga aaggtcagat gccgggccaa aggaaataag acagccgcgg tgagttcgtg
     2521 ggtgatttcg tggtcggtga atgtgcgcac cagcagggct gtcaggtcac cttgtgcgag
     2581 acggtcttgc agatccacga ggacgccggc tcctaattcc aaaccccaga tcttgaggag
     2641 ggtatccatg cttgcttgtg tgtccggatc gagtagaagc aggaggtgac cgccttgtgc
     2701 gacatacgtc tgaatgcggt cctgttcttc cttcgtaatg gcgcgtcggg gcccggcaat
     2761 cacgaggacg tctgtgttgc tcgggacagc agtctcttgc agcaatgtca cggtgccaat
     2821 ctcgtacccc tgcttttcca gcacttcctt ggtgagtgcc attccgccac ggtccttgtc
     2881 ttccaagctg cgttccccgt ggccttctag aaacactacc cgttttttgc tgtccttcga
     2941 cactcgcacg agtgcgccgg tgatttccac ctctgctggc gacgttatgc gaaccgattg
     3001 tgggccactt tcaaagatcg ccacatcggt gcgggtgacg ccgtaattct gtgcgacctt
     3061 cggctggcgt tccggatcga tgaactgaac ggtcagcttc gggctggctt gccgatagct
     3121 gtcgaagcgt tccttgtagc cctggtaccc aggatctttt tcccgcgtga acaccgtcac
     3181 gttgacgtct cgggtgagat tgcggagaac gcgataggtt tccggtgcga gcgtatagtt
     3241 ctgattctct gaaaagtccc agcggatgga atgtctggcg gcgaggaaat tcaagatggc
     3301 taagatggcc agaaagaggg caaccatcat cgcactgttc gcgcccattc gcgtggaccg
     3361 ttgagaggag aagcgtttga cctggtcaaa atgtgtagca aacgcccaaa taaaacaggc
     3421 caaggccagt ccctccagga gggtgacgag ccagagcttg tccggaacta gagagtaggc
     3481 aatcactccg gcaatggcca gccctgttcc gatggcaccg ataggaaggg gattgcgtgt
     3541 catttccatc gcgaggcatc cacaatccgg tgagcgagga acaacatcag tacggttccg
     3601 ctgacgtaat acatcaggtc tttcgtgtcg atcagtccgc gcaccaggtg gtcatagtgc
     3661 tccatgaagg aaagatagga gacgacttgt cctacgggcg tgtcgcccag gagcgagccc
     3721 agtccggcca gcagccagca catcagcagc agcccgaagc tggtgaatgc ggccacaatc
     3781 tggttttcgg tgacagacga ggcaaaaagg ccaacagcga gaaaaaaccc gccgagcagt
     3841 aacaagccca agtagccggt gaatacgggg taccaatcaa aatcgctgaa gagtgccagc
     3901 gtgagcggaa ccaaggtcgt caacagcaac atccccataa atacgagata gacgctgata
     3961 aatttcccga cgatgatttc gctgacacgg atgggggcgg tcatcaggaa ttcaaacgtt
     4021 cgaagtttgc gttcttcggc cagcagtcgc atggtgagga tgggaaggat cagcagcagc
     4081 acgaatcgca tgctggcaaa aagattgcgg aacacgagat cattcagatt gatctgcgcc
     4141 gtgccgcctt gcatttgcat gagttgaatg gcctgggctc cggtgaagac aatgtagaga
     4201 taggccagga atccgaaggt caggagaaag actccgccga cgacatacac gatcggcgag
     4261 acgaaatagg agcgcaactc ttttctaatg atcgcttgga cgggtggcat cgcttagtgg
     4321 tgctcgcctg gggtggtgtc gttcgacttc ggcggctcgt cttcccgttg ggtcagcttc
     4381 aggaagacat cttccaatgt catcgagacg ggtttcattt ccaatagccc ccagttttgg
     4441 ccgacggcaa agcgcgccac gtcctcccgg atatcccgcc ccagcgcgca ttcgatgagc
     4501 accgtgtgcg ggtcggctgt ggtcagcaca tgttctattc ctgggacctc gcgaaatcgc
     4561 tccgccagat tgaccggcgg agctttcagg gtgacgctga tcttttccga cttccggagg
     4621 cgggcggaga gttggtcagg agtgtcttcg gcgacgatcc gccccccatt gatgatcacg
     4681 acgcgctgac agactgcggt ggcttcgggc aggatatgcg tgctgagaat caccgagtgc
     4741 gagccggcca ggctcttgat caattcacgg atttcaatga tctgcttcgg atcgaggcca
     4801 accgtgggtt cgtccagaat gaggacggga ggatcgtgaa tcaaggcttg ggccagacca
     4861 acccgttgac gataaccgcg tgacagattg gcaataagtc gctgccggac agtccccaaa
     4921 gaaagccgtt ccgtgacccg ttccagcgcc tgcgttagac ctgttccgct caatccgcgc
     4981 agcttcccca caaaacccaa gtactcggcg accgtgagtt cttggtagac aggcggagtt
     5041 tccggcaaat atccaattcg tttctttacc tcgtcaggct gttccgcgca atcgaagccc
     5101 gcgacgtgcg cggttccttc cgttgcggga atgaaggagg taaggatacg catcgtcgtg
     5161 gttttgccgg cgccattagg gccgaggaag gccagcacct ctcctttttc cacgcgaaag
     5221 gtgacgcgat cgatcgcggt gaggtggccg tagcgtttgg taatgttaca aacttcgatc
     5281 atgcagtcgg gattgacggc tggctggtgt gattcctgct gttcgtttgg tacggcacgt
     5341 ggtgtggcaa atcgcgcctg atattaccga ccgtgtgaga tgcagtcaag agaaggatac
     5401 gttgtgctga aggacgtaga aaagcgtgag tccgtcttta cagcgtgatt cgtaactgct
     5461 acagttccgc gactttagcc accgggcggc ctggtggaat gcctgacgaa gaggtctctc
     5521 ctgaatgaag agtgacatga accaagcgag gccgagtttg ctcggcgtac tcgtcatcgg
     5581 cgccgcgttg tgcgtggctc ttgccggact tggaagtttc ctgacatcag tgtatgccgc
     5641 cagtaatacc gtccatgaga tcaaggggac ggttgagaac gtgcatgccc acgaagaccc
     5701 ccctgtcatc gtcgtcaagg ggcagcatgg gtcgagtgaa gctatcgtgg tcggggcagt
     5761 ggttaagcaa ggcgccacca ttatgcgtgg gaaaaaacgg atcacgctcg atcaaatcca
     5821 tgctggagat aaggtgacgt tgaagtatgt gaagactcgc gatggtctga cggttcgatc
     5881 catcgcactc catcgcaatt aatcacgcgc attcattctc gtgacgttgt gtttttcaca
     5941 aggaggtaga gagattttat gattcgacag catgtggtgc gggggatgtc tgcgccggta
     6001 gccgtcgggt tgctgctcct catgggctgc tccgggaaag gcgatatcat tccgatgaat
     6061 ttgaccccca aggccaagga gatgaccaac gcctcttcag cggttaagcc gatggcggga
     6121 ccgaaagttg tggtcattcc atttgaagac gcgcgggccg accatgccaa ggtgggaagt
     6181 cgaagctcca tgtggggggg tgaaacggac tttcacgtct cgagcggcag tgccggtgag
     6241 gaaaccggtc aagcacttgc cgactatctc aagcgcaaag gctggctggt gcagtatcag
     6301 aaggctgccc cagcggaatc agaaaatggt cccaatatcg tgttgtccgg aaaaattctc
     6361 gacctgacgg tcgatgcgaa gcggggattt ctcatgacag atattgaggc ccgcagcaag
     6421 ttggttatcc aggcaaacaa tcgggaagat ggcagttcga tcgttcgaac cgatgcgcat
     6481 tccggtagcc atgacaatgt attttggttt gatccccagg acggggaaga gcttctcggt
     6541 gaagtgctgg aaaagaattt tgagcgattt gttttgaaca cgaaactgga agatcggtcc
     6601 attcggtttc ggtagagagc aatccggagt tggggcgctt taggtcctga cagatcgtga
     6661 cgttccgtcc ttttgatctc tggggggacg ttcatttgtg aactgtactg tcgtgtaaag
     6721 acttagagtt ctggcagtgc tggctcattt gaaggcagtt cggtctttag tcgcgtattt
     6781 ccggcgggaa aaaccgcaac ttgtgttcag tgatgcaagg ttcgttgccc atttgtaggg
     6841 ggccttgcta cccagacggt attgtcgcca aggggaatct cccgtagcct gaaatcactt
     6901 ttgaggagcg gttcaagcag acagtggttt caggctttca aacgaggtgc ttctatggtc
     6961 aggaatttct ggaaccgttc tcgttgtaag acgggatctg ctcttgctcc cctggtagcc
     7021 tgcctcctcc tcagtgcctg ttcagccctt cccaaaggcg atctccccct ggatctcggc
     7081 atcaaggatc gaggcgttgc gtcctggtat ggaaaggagt ttcacgggaa acttgcagcg
     7141 aacggggaag tctttgacat gaccgcctat acggctgctc atcgtaagtt gccgcttggc
     7201 agtctcgtgc gagtcgtcaa cctcgccaat ggaaagtcgg ttcaggttcg aattaatgat
     7261 cgggggccat atgtctcagg ccgaatgctg gacctttcgc aagccgcggc tcgcgaactg
     7321 ggtatgctgg aagccggcac tagccctgtg cagatagaag tcatcggcaa tcatcgtccg
     7381 gtggcaccga taccctcttc actgatagcc tccgtagctg gtatgttgtt gaataccgat
     7441 acgcgagtca tgaagcggca tacgcgccag gaagaggggg tagaagtgcc tgtcgtacct
     7501 ctccgaatga tgccccaaga agcgttgtac gttcgccgtg aacggcggat cggcagtatg
     7561 ttagcggcag accattcggc gcataatacc gtccccgggc tcatcgtttc ctgatacgag
     7621 caatcgacat tccctcagtt gacacctcct cctgcacttg attagactgc ccgatctaga
     7681 ttggcatgct gagcatgccg ctatttccgt tgatgttgat cctaactgtt ggaggttgac
     7741 gctgaatggc aaagaaaccg accggtgaat cagacgaagt ccgactgaag aagaaaatcg
     7801 ccgctagcac taaagatgag agcaaatctg gtgttccagc cgtgcggtcc ttgcgtaaac
     7861 gactcaagcg ggtgcagcgt aaacgacgag cactcgtgtt aaggaaaaag catgcggcag
     7921 ggaaacaggc tgaagcaaaa tcctgatgaa ctgcagtatc gaagcatctg accctactcc
     7981 aaccctcctg cggaataagg attcttgata tggaacatac tggcgaaaaa aaagatcaag
     8041 cacaggctgt ttcccctgtc ggcccagtcg aagacgaggc tttgacagat caagtctctg
     8101 accaacttgc cgcatccttg gattcctccg tgggggagca ggagctcatt gagccaatgc
     8161 aggaagtcgt gctggaggag gagaaggtca aggatgaaat cgatattcag atcgacctcc
     8221 tcaaagatcc tgattgggtt gtgcggcggg aagcggcaat tacgctgggc gagatggggg
     8281 acgaacgttg cgttgaaccc ctcgcggcag cccttcgtga cggtgactgg caagtgcgag
     8341 aggtcgccat tgagggaatc ggacaaatcg gatctcctgc cgttgatgta cttctcaagc
     8401 ttttgcgcga ttgggatgtg cggaagtctg cgatcatggc attgggaaag attcgtgatg
     8461 agcgggtgtt ggagccgctc atgcagcagc ttcggaatga tgaattcatg gaagatgcga
     8521 ccgatgccct ggtaaacctt ggcgagcccg cgttgcccgg gctgatcaag gctctaaagg
     8581 acaaagagga gttagttcgg aagcaagccg tgatagcgtt gggccgcatt aagtcgccgg
     8641 aagccatcga tccgttgatc gagatgttgc agaacaaaga ttggtttaca cggctgacgg
     8701 cggcggccgc gctcgaagct atcggggatg aacgtggtcg cgaagcgatt aagcccttgc
     8761 tgaaagatac ggatatggtg gtcaagatgc gggtcgagcg cattcttgcc aaatggaaga
     8821 agcagccagc cgnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nncgcggcgc
     8941 cccgccgcgt tgatgctgtt gggatcgcac aaaatattca atctgttgtc aggtttattt
     9001 attggaaaac ctgagccaat ttgtcgagcc tcggggttgg ccggtttttg cggactttcg
     9061 aagttgagcg aaaaaaccca gctgatgagg gctgagcatg tcggctcagc ccttacgggt
     9121 gctgactttg tcttttcgag agagtatgcg aaggagactt ccggcggaag taatacgtac
     9181 ggccgcatca gaatcttgca agccaatttt agcggcagga atgagcgatt ttagcggaga
     9241 ctttcccagt gcgcgggctg ccatgagccg aggaagcggt tgctggtctc gtagcaggtt
     9301 ttccagaatc gggagcgcat tggcggtggt cgcgagggcg agcgcgtggg cggtatcgcc
     9361 gcgtatggat ggatcgggat gccgcgcgag ggctgccgcg ttcaaaatga caccggtatc
     9421 gcctaagcgg agcagtgatt ccactgcgct aattcgcaca tgttcgtctg agtctcgtaa
     9481 cagcggctga acgacgcttc gtgattctga aactcctagg cgaccgaggc tggaggccgc
     9541 aacgctgcgg acgcgcggat cttcatctcc cagggcgtgc gtcagtggcg cgatgccttc
     9601 gatactcccg aattctccca aggcgcctgc ggcaaaggca cgcacggcag gatgaggatc
     9661 atacacggcc tgactgagga tcgagaggct ggcagggcgc ttcaagcgcc ccaatacccc
     9721 caaggccgcc atacgtactt cggggtcagg aagagtcacc gcactcgaaa tatccgtcag
     9781 cacatctgtg cggccaagtt tgtacaggcc tgcaaacgcg aagatcgatt ctggtccctc
     9841 atcgacgcgg gcaatttcgg tcagttgatc ggtaatacct gacaccttgg catcgctgag
     9901 agcattgatt gccgcaatac gcacgccggg cgcttcatct cgaagcgcgc gtttgagcgc
     9961 ggccgaacgt cctgccagtc cactccgccc aatggcttcc gcagccctgg cccggacaag
    10021 tgccgaagaa tccaacagtc cgtcttcgag aagggggagg gtatcggctt cccccatttc
    10081 tgcgagtgcc gtataggccg cgatacggat atgttcttgg gagtcacgga ctcgggacac
    10141 gataaatgct cgtgcgattt cccgtaataa cgccgggtca tcagggcgat ccccagcggt
    10201 aagcttgggg taaagtttcc atgcctcttc aggttttccc atcttcacgt agctgaggat
    10261 ggcgtaacga atggcttcca ggcttggttc ttggccggtt ggagggtgct gaataagatc
    10321 gatgacacgg ctgtactccg ccgcccgata gaacgtcatg gcatcccgtt ccagtggcga
    10381 cggcgaggtt ttaggcgtgg aggtcgctgc ccctaccggc aggggactta tccagaccat
    10441 taacaggagt cctgcgggaa atgcccaggt ggagatgtag cggcctggca tgggagaaga
    10501 cctaattcct gctaccattt gttcggcgta cgggcagtcg ccggcgcata cagctgccgc
    10561 atgtattctt tgaccattcg tttggtgcaa aagcgcggag caaccgtctt gatgctctct
    10621 ttgacaatgt gaagccatcc gcgcgggatt ccatcgagat cccgctgata aaacagcggc
    10681 acgacctctt gttctagcag gcgaaagagt tgttcggcat catgcgcatc ttgggcttgg
    10741 gtgtccgagc cttcagggag aggttgaatg ccccatccat tggcgccgtt gtagccctcc
    10801 tgccaccacc cgtctaacac gctgaggttg atcactccgt tcagcgccgc tttttgaccg
    10861 ctcgtgccac tcgcttccaa cggcgcacga ggcgtattca gccagacatc gaccccttgg
    10921 accaaatact tggccatatg catgtcgtag tcttcgagaa acgcgatatg cccgccgagc
    10981 ttgtgatcgt tacagaagtt caggacttcg tgaataaagt aacggcccgg ttcgtcggcc
    11041 ggatgggctt tccctgcgaa gacgatttgg actggccgcc agcggttatg gagcaattgt
    11101 ttgagacgtt ccaggtcacg aaacaggagg gttgcccgct tgtaagtggc aaaccgtctg
    11161 gcgaacccaa tggtgagagc ctctgggtcc aacagggttc ctctggcgat ggcttgcatg
    11221 ggctggagat gtccgcgaat ccatccgtcc cgcgcgcgct cacgaatgaa tcgcatgagt
    11281 ttgcgtctgg tggtttgccg aaccgcccag agggcgtcat caggcaggtc tgtaacccgt
    11341 tgccagatgg tcgggtcgtc gatgcgctcc gcccagtcgg ggctgagata tttggcatag
    11401 agcgagttcg attccggaga aatccatgtc ggcgcgtgaa tgccgttcgt gaggctgcgg
    11461 atgggaacaa gatcctgcgc cagaccgggc cacagatgtt gccacatttg gcgagagaca
    11521 cggccgtgtt cccggctcac gccatttacg tgggctgata gccgcatggc gagcgcagtc
    11581 atattaaagc cgtgaccagc gctttccggc gtttctccaa gccgcaaaaa ttcttctctc
    11641 gatagtccta gctggcccca gtaattgtga aagtaccggt ccatcagatg gaaggggaag
    11701 atgtcatgtc cggcagggac aggggtatgc gtggtgaaca ccgtgctttg ccgaacgagc
    11761 tcactcgctt cggcatggct gtgtcccgtg ctgacgaact ctcgaatccg ttccagcgtg
    11821 aggaaggcgg aatggccctc attacaatgc cagacggctg gggtgatgcc gagggctcgc
    11881 aggacgcgga cgccgccgat gccaagaaga aattcctgac acagtctcgt ctcctgatcg
    11941 ccgccataga gtctcgccga aagcgcgcga tcttcaggcg tgttttcagg cacatcggta
    12001 tcaatcaggt agagggacat ccgaccattt cggacctgcc agacaagcac ggtgacttga
    12061 cgatggccga tttgaacttt gatggtgcaa ggaacgccgg ccggagtcag cgcttggtga
    12121 atcggcgaat catatctatt gaagggcaca taggtcgctt cctgccaacc ctcaggattg
    12181 attcgttgtt tgaaataccc ctgcggatac atgaacccga tccctacgag cggaatgcct
    12241 aagtcgctgg cctccttgca atgatctccg gctaagatgc cgaggccgcc gctgtaaatc
    12301 ggaattgaaa tgtgcagtcc gaactccgct gaaaagtagg cgatcggaga attctggagt
    12361 gcagggaatt ccgtggccgc ccacgtgttc ttgctgctca tgtattcgtc aaagctgcgc
    12421 aggacggcgg agtactgtcg tgcgaaggtc ggatcactgg ccagcgtcgc gaatcgttcc
    12481 ggtttcactc cagcgagtaa ttgaacggga ttgtggtggg tcaggaacca caaggttggg
    12541 tcgatcgact caaagagctg ccgtgccggt tggttccagc tccaccacaa gttgcgggcc
    12601 agttcgccaa gtcgatgcag gctttgcgga accatatcct gagggggctg tatgtggtca
    12661 ggtgcttgca cgacgcctcc gtggaaggtg atcgatgggt gaggaagggg ccggtatggt
    12721 cccgcttccg gaatgctgtg tcaggcgtgt ccggctttat gccaggaggc ccattggtca
    12781 gaaaaggcga cggtggcgta gcgctctccg agaatcttgg cgactcgatt catggtggcc
    12841 gtcagttgtt tcgcctcctc ctgtgtcaag tcttgacgaa aacgcgggtg gagtccccaa
    12901 cgcgtctcaa cttcttcgcc cttgatgctc gacatgacgc tcaccagctt aatatcggcc
    12961 ccggtggcgc cccgagggtt gctgctggcg gcactggggt tcgcattgcc tgtggcgtcg
    13021 gccgggactg ctggcgtctt gccttcaaag atgccgatca gagccggaat gacagcggca
    13081 atgcagagtg tcgccgcggc ctcaaccttc gggtttcccg atgccccgac cgcacgggcg
    13141 acacgatcgc tgaaatcgcg atacaaatca tttttggccg ggctctcctc tgtaaccagg
    13201 aatcgatacc gctcgtatgt ctggcgactc tcggatacag cggccccgat cgtcatgacg
    13261 atttccatct ggtcatcgcc ggctccgaat gccggttcca atactttctt gagctgatcg
    13321 atcactgtat ccgtcagttc gtccatgaac tgcggttgtt ccctcagtgg gatatggagc
    13381 gccgataccc gatcggtcag attgaacatt gcccgtaaaa attcgagata aatgccccat
    13441 tcgtcctggc gcttcagttt gagggcctgt tccggcgccg cccgtttgat caccgagacg
    13501 gattccccag acacggcaag catcagttcc gccacggtgc gcatctgttg agcgaacgaa
    13561 tgtgatttag tcgtcataat ggttccctgc tggtcgggca ttatatacaa ctcaccttga
    13621 agctccaagt gttgatctcg tgcgccctga tcatggacgg tggctcgcgc gctgtcgttg
    13681 caaggcacgg ggtggtatgt tatacagcgc gaccgctccc gtcatgagcc tcaccgccca
    13741 atcggatgcc aacatggatc gagacacgaa accctacatt ctcaaacgga ctccggatca
    13801 ggacgtggtc cggaagttct cgttggatta tgccaaagag ctcaatcccc agcagtatgc
    13861 ggcggtgacg gccgcggatg gcccggcact cgtcattgcc ggagcgggga gtggaaagac
    13921 gcgcaccctc gtgcatcgcg tcgcctattt gatcgattcc ggtgtcgatc cgtcccagat
    13981 tctgttgctg accttcaccc gcaaatccgc agaagaaatg ctggagcgtg ttggcgcgtt
    14041 gatcggctcg cgcagccaac gggtgtgcgg cggtacgttt cactcggtgg cgaacatgct
    14101 cttgcggcgc tacggtcgag tgctggggat tgagccaagt tttaccatta tggatcgcgg
    14161 ggatgccgag gatctgattg ctctgttacg cgcccagctc ggactcaatg agaaggataa
    14221 gcgtttcccc cgcaagggca ctatcgcgga aatttacagt aagtgtgaaa acaccttgcg
    14281 cgggctcgaa gaaattgttc ttgatgagtt ttcgcatttt gccgatcacc ttgatgcact
    14341 cggcaaactg caacgcgcct atcagctggc caagcgacag cgtcaactgc tcgactatga
    14401 tgacctactc gtcttattgc gcgacctgat gacgcaggat gaggcgagcc gacaggctat
    14461 ttcacggcaa ttccgttaca tcttggtgga tgagtatcag gatacgaatc ggctgcaggc
    14521 ggaactcatc cggaagctgg cggccacgca tgacaacgtc atggtggtgg gggacgattc
    14581 tcaatcgatc tacgcctttc gcggcgcgac gttccgcaac atcatggaat ttccctcctg
    14641 gtttcccggc gcgaccattt ataagcttga agaaaactat cgcagcacgc agccgattct
    14701 cagtctggcg aatgagatta ttcaggaggc gcctgagaaa tatacgaaac atctgttcac
    14761 gaggaagctg gatggaccgt tgccggcgct ggtcgaggct gccggggaaa atgctcagtc
    14821 tcgcttcgtc gcgcaaaaga ttctagagtt gcgggaggag ggtgtcccgt taaatgaaat
    14881 cgcggtgtta ttccgttcca gttttcactc ctttgattta gaaattgagt tgtcacgctg
    14941 tggattgccc tttgtgaagc gaggcggcat caagttcatc gaggctgcgc atgtcaagga
    15001 tttgttggcc catttacgcg tggtggtgaa tccgcatgac gcggtgagct ggcatcgtgt
    15061 gctcatgctg gtcgaagggg tcggtccgaa aaaagcgcag gatctcgttg cagccatggt
    15121 gagggtgact gatccctatc aggtgttgcg ggacagtagc gggcggtcag ggaaagggtt
    15181 gaaagagctc gcggtggtgc tcgagaatct ttcgaagagc gacgatttga gcccgaccga
    15241 gcaggtcaat cgggtgtatg agtattacct gccgattctc aaagaccacc atgacgacta
    15301 tcccaagcgg attcgagacc tcgatcattt gcatacgatt gccgaaagtt accccggcct
    15361 aacggaattt ctggcggact tggctctggc tccgccggat ggcagtgcgg tcggagtgga
    15421 agcggctggt tcggacgacg agcaggtggt gctgtccacg attcattccg cgaaaggcct
    15481 ggagtggcaa tgcgtgtttc tgttgtgggt cgtggacggg aagtttccgt cggtgttttc
    15541 gttcaatacc gatgaagaat tggaagaaga gcggcgattg ctctatgtcg cggtcacgcg
    15601 ggcgaagcgc tatctgtttc tgacctatcc gatcaatgtc tatgacagga gctcgggcat
    15661 gttgttgtcc aagccttccc ggtttttgga tcatgtgtct cctcgcttat tcgaatcgct
    15721 ggcgttggtt gaggaaagtc acggccatga ttggggtcat gatcgggacc gttacgtcta
    15781 ggggccttgc ctaattccga aaatcctccc gtgatgttca tgtcccaatt cgaggccatc
    15841 atgcggtgtc tgcggtccta tatcgattct atgcaaggtg tcgctgcagt gatggtggga
    15901 ggcatgctgc tggtgctgct atgttctgcg ccgattctgg ctgagactcc ggcggcccag
    15961 cctgatgcct ctcgcctctg gagcggcttg gtggcggaag cgaaagccct ccggctaccc
    16021 actcaatttc ttgagcaagt gccgaagcat tttgtgacat tcgaattcga ggatctgcat
    16081 gcctttgccg cggagtatca tccagcggac catcgcatgg tgctggatcg atcgctgtcg
    16141 ctgaatgcgg cgggccgcac gttgcgaccg ttggggcgat tgacgcataa ggagctggaa
    16201 acgctgtatc acgagctgtt ccatgtctat atggactttc tcgagcagga agctacaccg
    16261 tcggaagccc atgcttcctt gattgcgttt gcgcgcgagc aacagcattg ccgatatcaa
    16321 caggtcctga tcacaccggt gcttcagaaa agggcgctca aggaagagcg atttctgagt
    16381 gagacggaat cgtgggaagt tctcaatgaa acctgggcgg tgtttatcgg gtgggcggtg
    16441 tggacgcagt tggaagtcga tcaaaaaccg cggcgtgatt cccggggacc tgcccatacc
    16501 tctggctgga tcgcgcggct cgatcaggcc gagcaggacg cggcgttgat tgggtactac
    16561 gaacctgagg acctggagga gaaacgtatg gcgcgcaagc gatttctggc gccagagttt
    16621 cgcctgtctt caccggaact cctgcgcctc atgaaggatg tattggggag tcagccggac
    16681 gtcattcgtc aagccactca ggtgcttcaa cgttcgcgac cagttgccag tacgcgcggg
    16741 gcctgtgcgg catcaacgaa gccgtagaat tgttcctgca tagaacatac ccccttgaca
    16801 atagaacgcg tcgcaaataa aatcggctgc tttcgaagcc agatcgaccc tcaccttatc
    16861 agcgatccag ccctgtcgct ttgctggaga gctgtgcatg gtggggctta cttcattctc
    16921 tgaaccggaa aatgaaacgc tctggtgctt gttttctttg aattgatttg tcgcgcgctt
    16981 acgtttggaa ataggaccct cgcgggcagg tacccaagtg gacaaagggg gcagactgta
    17041 aatctgctgc cttatg
//
LOCUS       DAOQPD010000087        16627 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1744_length_16627_cov_20.221820, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000087 DAOQPD010000000
VERSION     DAOQPD010000087.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 16627)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 16627)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16627
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1744_length_16627_cov_20.221820"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..493)
                     /locus_tag="PK063_15860"
     CDS             complement(<1..493)
                     /locus_tag="PK063_15860"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HMZ98576.1"
                     /translation="MNRPIDNQHVIEIKPLPSPRDVKTQLPISDEVSELVFQTRQAIR
                     NILHGRDMDRLIVVVGPCSIHDPDAAYEYADRLKPVAEAVRDKLLIVMRTYFEKPRTT
                     VGWKGLINDPHLDGTCDIAQGIQLARTILLNINGKGLPCATELLDPVTPQYIADLLSW
                     TAIG"
     gene            674..994
                     /locus_tag="PK063_15865"
     CDS             674..994
                     /locus_tag="PK063_15865"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98577.1"
                     /translation="MLPRYASVRFSSTIALLLVTLLLAMAPFAAALEIHHELAAADHD
                     GHEHSDTDLCQWVQYHTGHSLIGDVPVPCAFLAHAPPQLMPAPVLVSQSLPASRASRA
                     PPQR"
     gene            1113..3521
                     /locus_tag="PK063_15870"
     CDS             1113..3521
                     /locus_tag="PK063_15870"
                     /inference="COORDINATES: protein motif:HMM:NF012801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HMZ98578.1"
                     /translation="MVWCLGGWLGAFSVLVAHAQQPAGDASRTVVGIVQNQDLRRVPQ
                     AAVQVKDQEGTVIVTAVANEAGEFTVDLPSQGTYSVSAQMDVDRSEYLILKSGAEPVG
                     PVTLTLAKTNEISLEVVSPLAPIQYKASSETYALSRKEIESLPRGNNNDLQDVLLTIP
                     SAVYGSLKQVHIRQDHANLQLRIDGVPIPDTVSSTFSDVISPRAWDRADIILGGMEAQ
                     YGNKAAAVLDITTKSGTKPAFGSVQMMGGSNGTLNPSFEYGGTVGEKFRFYILNSHTA
                     TNRGIEPPTLGHSVFHGQSERNQTFIRGDYQHDNKNNFTWLFLNSVAKYQIPTTPGLE
                     LDPSGQMLPLLQAGRPGFTPVASQAINEFQKENNQYGHMVWRHDVNANNFFSLAGYMR
                     HTRATFNTDPLNVLAYTADPTQPFSSADQDRNAYSTGLRFDYTYVHSKEHLIKAGFQL
                     DRTQSVNKTRLFTFADDGAGNPTGDLLSLNADNRQIGYRQEFWIQDQWSPTDKWTFNL
                     GLRGDAVQYLRNEGQVSPRLGATYKYDQSNVFHAFYGRMFTPPNLEAISFAKLNTLGT
                     RAQPEDVTNNTVRAERAHYFEVGSYHALNRYATLQFTGWYKLSNFLSDAGQFGTTPLL
                     NYFAFERGWQRGIDGALKLQLTDNLTARGNVAWGQCKGYGLQSGHFLLEAKEIADINS
                     RGGVFCDHMQTLTSSAVVTYKFLERTTMTGQMLFASGLRTAENEEAKTNSTHSPSYTI
                     YNLSIAHVFPLPWDGQKFLLGFDIINLLDQKYYINQGEGSIGLGVAHAGMPRSFFFRG
                     QWFF"
     gene            3837..4298
                     /locus_tag="PK063_15875"
     CDS             3837..4298
                     /locus_tag="PK063_15875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy transducer TonB"
                     /protein_id="HMZ98579.1"
                     /translation="MTNIIDGIRSLTVPMVVLGMWCLLPVYAIAVTGDEATHEADHAL
                     DAEIIELPEVHVHGLPLNKDQQVGPVPKSTPWPAIPSSLEGKPLDDWMKARLLVSKEA
                     QVTVVVLESAKHRELTIAGIIALNKWTFAPQLKGDDPVDGELTVRIHFRSQ"
     gene            complement(4349..5836)
                     /locus_tag="PK063_15880"
     CDS             complement(4349..5836)
                     /locus_tag="PK063_15880"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98580.1"
                     /translation="MMIRNVFGLLLPLALTAQLAGYAALVVHAANEKQGAQHYELSRG
                     AGEKRSECVGMVRIGPGIAAMDLEATRTDSDDAQISLRGTRDSFVCEAILHPAMRAVL
                     GRSIVQFHNGTTLPLAQVLRQILEAGKQPRMAQTVTSTALDRIQVHALHAVVVYEGKA
                     HLPDSHPIETPQGTIHITVEKTREPITLFLMSYNPVDWRISAVPGARIGSVILRGYYR
                     QTIRGLDKTVPVNTASTEDDNWDDLFPRTLVTSRDGLIDFKAYVRAMAGVEPATVQSL
                     HTGDSIVIDGKTTLEFPAPIEVPITQPVVFKSESESSARFRGRNMISPDRLTVGYGMS
                     GASTESIATMPHSSGRWYAEFIVHAGADNAVPISWTNVGIRSTANESGGLTSHGGQLA
                     YGVKQYLRNVGGLRDKDVIGLAMDLTRGHLYVRHNGVWVGGSPDSGNPILQIVRDRQY
                     VVAVEVGSPGGDYSKSDTWSGNFGATPFRHPVPDGFLPYEGRRPK"
     gene            complement(5945..7579)
                     /locus_tag="PK063_15885"
     CDS             complement(5945..7579)
                     /locus_tag="PK063_15885"
                     /inference="COORDINATES: protein motif:HMM:TIGR01845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux transporter outer membrane subunit"
                     /protein_id="HMZ98581.1"
                     /translation="MTCFRSRPAPCVSGERADARRFTDLARTAALLLALSLSACSTFP
                     AVDLSPPYEPAQFVVPASWHGSSPFVEAKPSDGELRQDWWTLFKDPVLNGLEAQALTA
                     NPDLQAAAERFVQSRDVMMKARSQYLPRVGLGFDATDNRQSLHRLFRAPDSPLEESSV
                     VGGGLASWEPDFWSALRNATKVEIYRAEERAADFGLARLSLQAEVAANYFALRGLDAQ
                     DAIYTQSIALYTQSLELVNAQFIGQIASALDVARVESLLFSTETRRAQIQGQRQVLEQ
                     AIAILLNVAPASFTIAPVNDLKMATFTIPQTLPSTLLERRPDIAAMERRMAQANRTIG
                     IARAAFYPNVSFRLGGGFEDEAFNLFSLANSFWSYGSGVSLPLFQGGYRRAQLQQSWS
                     AYRETEDRYRSTVLNAFREVENNLSLTNRLTLAANRQDAAVGATLKTQDLTMELYQGG
                     LASSLELIYAQVAMLTARIESVQIKAELLRTSVALIRSLGGGWNRQQLPTDDEIQPFG
                     TFQYVNLDKPPSVRGIDVNAENNRLHNDLTKKPAVR"
     gene            complement(7576..8778)
                     /locus_tag="PK063_15890"
     CDS             complement(7576..8778)
                     /locus_tag="PK063_15890"
                     /inference="COORDINATES: protein motif:HMM:TIGR01730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HMZ98582.1"
                     /translation="MLKRLSPRPGVLLGIVLLLFYLSYRIYESNVDATTLRKHTLEDT
                     IPTVAITYPKPVPPTETITLPGNIQAWFEAPIYAQVSGYVKMWYKDYGALVQKGDILA
                     EINAPALDAQYAQAKADLAAEQAKYALADLTAKRWVALRKNHAVSEQSISVQEANAKA
                     EAARVKAAEQNVKNFEALIQFKTIVAPYDGVVTVRNINVGDYINKEGNISNRSSITNL
                     FTVADVSMLRLFVNVPAAFGAFLKPGLTADVTVPQLPDRHFTAKFLTVARGFDVSTRT
                     AVTVFTIDNEDRALWPGSYAKVHLTAPVDRNVLTIPSTALVFQEHGTQVAVVAEDDRV
                     QLKPITVSKLMDNAVEVSGGISSQDRIVNNPSAALLEGDKVRVVTPAPGYDLVGTATP
                     LAKEPALK"
     gene            complement(8778..10475)
                     /locus_tag="PK063_15895"
     CDS             complement(8778..10475)
                     /locus_tag="PK063_15895"
                     /inference="COORDINATES: protein motif:HMM:NF013069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HMZ98583.1"
                     /translation="MSKPLEPAEQPGPVVSGNIFVRFQQGFERGFNRFRERYGLLLER
                     AMARRRAFVTVCLVIAVASLSLFFFLGRDYFPEIRSGVIQMHMRAPLGTRIEVSGRIA
                     TLVSNSVEELLAGEVENIVSNCGLPVGAHNLAFIPTPTIGSQDCDLTILLRDEKSPVW
                     EYRRILRKGLTERYPGTEFTFQPSDLTAKILNFGAPAPIDVQIKGPDMHPNYEFTRKL
                     AGRLRQIPGATDVVIQQTMRTPTLMVEGNRTFGLAVNRTQKEMASNLLMTTAGSQQID
                     QVYWLDPKTGMSYLINVYTPQAQVNSVNSLRTIPVEPSNDVSDNNHDVQLLGNLADLS
                     AEGTPGVITHANIMPLFDIYVGTEGRDLGGVLADVETVAKSMEHELPRSAAIEIHGQA
                     SLMHDAYFELIFGLLAAIVLVYLLIVVNFQSWLDPFIIITALPGALAGIAWALFLTHT
                     RLSEPALTGAIMTMGTATANSILVVSYARERLETHGEALRAAIEAGTTRFRPVLMTAS
                     AMIFGMVPMATGYSQNAPLGRAVIGGLLVATIFTLFFVPCVYAILYDGRSVPAKEQL"
     gene            complement(10459..11958)
                     /locus_tag="PK063_15900"
     CDS             complement(10459..11958)
                     /locus_tag="PK063_15900"
                     /inference="COORDINATES: protein motif:HMM:NF013069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HMZ98584.1"
                     /translation="MNEIVLIALRRPYTFVVMSILIVLLGSITVLHMPTDVFPNITIP
                     VTSVVWAYAGLLPQQVEGRITYLFERFLTSTVEGIKYIHSHSYYGSSITNIFLQDGVD
                     VGRAEADITAIAQTVVKALPPDISPPMVMRLAPSSIPVAMLQISSDRLTPAELYNLAY
                     MRIRPLLVTVPGIVLPHPYGGQDMQVMVNLDQQKLLARNLTPADIHNALMQQYLVLPS
                     GDIKIKQTDWIVQTNASPMQIEHFSDIPVKREDNAFIYLRDVATVRLMGRVQQNAVLV
                     KGKQTVIIVAMKSTEASTLDVVNGIKKMIPRAEQISPEGVEIKLLDDASTFVKDSIAD
                     VLHEMATAGALVGLIVLLLLGSWRATVIVWTSIPLSILTALIGLHWLDETINVMTLGG
                     LALAVGILVDDATVMIENIDRHLEMGKPLEQAIVDAANQIVVPTFVATLCIAIVWIPL
                     FELGGVAGYLFKPMAEAIIIAMLASFILSRTLVPTMAKYMMKGHHVEAA"
     gene            12458..13258
                     /gene="modA"
                     /locus_tag="PK063_15905"
     CDS             12458..13258
                     /gene="modA"
                     /locus_tag="PK063_15905"
                     /inference="COORDINATES: protein motif:HMM:NF024921.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009897 - external side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015412 - ABC-type molybdate transporter
                     activity [Evidence IEA];
                     GO_function: GO:0030973 - molybdate ion binding [Evidence
                     IEA];
                     GO_process: GO:0015689 - molybdate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HMZ98585.1"
                     /translation="MAVGLVGGLAIGEPAEAENLTIGAAYSLKAAFQEVVPMFESEFG
                     ATVNVVYGSSQTLRREVESGAPVDVLLSAVEDLEKLQKKGLTLNGGPEVYAQTSLVFV
                     MSAASQAMPISFHDLLSERRTRVAIGAFESAVAGPITARALRAVDPSYKDRFRLISAT
                     HHDEVIEMIRREEAEMGLVYRVDAINNSGQVRIIDEMPGGTYTPVRFGQAIVWTCRDE
                     SRTAAEQFTDFFMSPRIQKLLLKYGFEPAASHVGENKVARTAPKVRVN"
     gene            complement(13265..16462)
                     /locus_tag="PK063_15910"
     CDS             complement(13265..16462)
                     /locus_tag="PK063_15910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0042908 - xenobiotic transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="HMZ98586.1"
                     /translation="MDFSKFFIDRPIFAAVLSIVIFAAGLIAIPILPISEYPEVVPPA
                     VIVRAIYPGANPKVIAETVSTPLEEQINGVENMMYMKSVAGSDGVLQMTITFRPGTDP
                     DAAQVQVQNRVSQALSRLPSEVVSLGVTTQKQSPTFLVMVQLLSPEGKYDALYLRNYA
                     NIKIKDELARLPGVGQVQIFGSGDYAMRIWLNPDKIASRGMTASDVVAAVREQNIQVS
                     AGQLGAEPIAKDTDFLISINAQGRLRTAQEFGNVVLKIGAGGEVVRLSDVARIELGAN
                     DYTLRGQLDNQDAPPIGIFQAPGANALTVRDAVIAKMEELKTRFPPGLTYRSDYDTTV
                     FVRDSIQAVVQTLMEAILLVVLVVILFLQTWRASIIPLIAVPVSVVGTFAALYLFGFS
                     INTLTLFGLVLAIGIVVDDAIVVVENVERNIEEGRTPLQAAHQAMQEVSGPIVAIALV
                     LCAVFVPMAFLSGVTGQFYKQFAVTIAISTVISAINSLTLSPALAAKLLKSHGTPKDA
                     LSRLIERLFGWVFRPFNRFFKASSNGYQGTVSRTLKHRGSVFAVYALLLIVTGMLFQA
                     VPRGFIPTQDKLYLMAGVKLPEGASLDRTDAVLRQVVAISKTVDGIAHVVAMTGLNPL
                     QFTNTPNYGIAFLILKPFDERHRSAKEISEEMNQKISAIKEGITFVLMPPPILGLGNG
                     AGYGLFVEDRAGLGFGALQNAVGGLQGAVMQTPGMGYPISGYQANVPQLDAEVDRVKT
                     KTQGIALTDLFATMQIYLGSAYVNDFNLFGRTWRVYAQADGDFRGKVEDISNLKTRNA
                     RGEMVPIGSMVKFSQTYGPDPVLRYNGYPAADFMGEADPTKFSSAQAMDTIRDIAGKV
                     LPNGMTIEWTDLSFQEASQGKAALLVFPIAILLAFLVLAALYESWTLPLAVILIVPMC
                     MLCALAGVKLTGGDNNTFVQVGLVVLMGLACKNAILIVEFARELELQGKGIVEAALEA
                     CRLRLRPIVMTSVAFIAGTVPLVLSHGAGAEVRSATGITVFAGMIGVTLFGLFLTPVF
                     YVGLRMLSGRKLIRHDEGMDVARPAGQLSGVENPH"
BASE COUNT         3458 a         4678 c         5101 g         3390 t
ORIGIN      
        1 ctccgatggc ggtccagctc aggaggtcgg caatgtattg cggcgtgacg ggatcaagca
       61 gttcggtggc gcagggaagg cccttgccat tgatgttcag caaaatcgtc cgggccagct
      121 gaatgccctg agcaatgtcg caggtgccgt caaggtgagg gtcgttgatg agacccttcc
      181 aacccacagt cgttcgtggc ttctcgaaat aggtgcgcat cacgatcagc agtttgtcgc
      241 gaacggcctc agcgacgggt ttgagccggt cagcgtattc gtaggcggca tcaggatcat
      301 gaatggagca ggggccgacc accacaatga ggcggtccat gtcacgtccg tgcaggatat
      361 tccggatcgc ctgtcgcgtc tggaagacca gctcggatac ctcgtcgctg ataggcagct
      421 gcgttttgac atcgcggggc gaggggaggg gtttaatctc tatgacatgc tggttatcga
      481 tcggcctatt catgatggtc cctttgaacg gtctctctgc taaggtgtga catgaaaatt
      541 gtgagttaac atagcgaaaa gtgaaagaga aagtccagag ggtgggcagg atcggcgcat
      601 tgccttgctt tcaaccgggc gctttgctac aaaatccaag tttgccgacg tgtccttaga
      661 cgatgagatg gctatgctgc cccgttacgc ctccgtgaga ttcagttcga ccatcgccct
      721 gcttctggtg actctcctgc tggcgatggc gccgttcgcc gccgcgttgg agatccatca
      781 cgaactggcc gccgccgatc atgacggcca cgagcattcc gataccgacc tctgccagtg
      841 ggtccagtat cataccggtc attcactgat cggtgatgtg ccggtcccct gcgcgttcct
      901 ggcgcatgcg ccgccgcagc tcatgccggc gcctgtactc gtctcccagt cccttcccgc
      961 atccagggct tctcgcgcac ctccgcaacg ataattctgc gccaccatat gtgcatcact
     1021 ggtgacctgc gttgagcacc gaggctgtgc ctcgctccgc gcaggcgggg aattttcgtg
     1081 agggagtcat gatgtcgtca ttgagaatat tcatggtgtg gtgtctcgga ggttggctcg
     1141 gggctttcag cgtccttgtc gctcacgccc agcagccggc gggagacgca agccggacgg
     1201 tcgtcgggat cgtgcagaac caggacctcc ggcgtgtacc ccaggccgct gtgcaggtga
     1261 aggatcagga gggcaccgtt atcgtgacgg cggtagccaa tgaggcggga gagtttacgg
     1321 tggacctgcc ctcccagggc acctattccg tcagcgccca gatggatgtc gatcggagcg
     1381 aatatctcat tctgaaaagc ggagctgagc cagtcgggcc ggtgacgttg acgctagcca
     1441 aaaccaatga aatttcactg gaggtggtgt cgccgctggc gccgattcag tacaaggcct
     1501 cgagcgaaac ctatgcgctc agccggaaag aaattgaatc tctcccgcgt ggcaataaca
     1561 acgatctcca ggatgtgctg ttgaccattc ccagcgccgt ctatgggtcg ctgaaacaag
     1621 tacatatccg gcaggaccat gcgaatctgc agctgcgtat cgacggggtt ccgataccgg
     1681 ataccgtctc atcgacgttt tcagatgtca tcagtcctcg cgcctgggat cgagccgaca
     1741 tcattctggg cgggatggaa gcgcagtacg gcaacaaggc ggcggcggta ttggatatca
     1801 cgacaaagag cggaaccaag ccagccttcg ggtcggtgca gatgatgggc ggctcgaatg
     1861 gcacgctcaa tccgtcattc gaatatggcg gaacagtcgg cgaaaaattc cggttctata
     1921 ttctcaacag ccatacggcg acgaaccggg gcatcgagcc gccgacgttg ggccattcgg
     1981 tgtttcatgg ccagagcgaa cggaatcaga cgttcatccg cggcgattac cagcatgaca
     2041 acaagaacaa cttcacctgg ttgtttttga attccgtcgc gaagtaccag attccgacca
     2101 cgccgggctt ggagctggat cccagcgggc agatgttgcc attgctgcaa gcagggcggc
     2161 cggggtttac gcccgtggcc tcgcaggcca tcaatgagtt ccagaaggag aacaaccagt
     2221 acggccacat ggtgtggcgc cacgacgtga acgccaacaa cttcttcagc ctcgccggct
     2281 acatgcggca cacgcgggcc acgtttaata ccgatccgtt gaatgtcctg gcgtatacgg
     2341 cggacccgac tcaacccttc tcctctgccg atcaggaccg taacgcctac tcgaccgggc
     2401 tgcgattcga ttacacctac gtacacagta aggagcatct catcaaggcc ggtttccaac
     2461 tcgatcgcac gcagtcggtg aacaagacca ggctcttcac ctttgccgat gacggggcgg
     2521 ggaatccgac tggcgacctg ctgagtctga acgccgataa ccgtcagatc gggtatcgac
     2581 aggaattttg gattcaagat cagtggagtc ccaccgataa gtggaccttc aacctcggcc
     2641 tgcgtggaga tgcggtgcag tatctccgga atgagggcca ggtcagcccg cggctcgggg
     2701 ccacctataa gtatgaccag tcgaacgtgt tccacgcgtt ttacggacgg atgttcacgc
     2761 cgccgaatct ggaagcgatc tcatttgcga agctcaatac gcttgggacc agagcgcaac
     2821 cggaggatgt gaccaacaac acggtgcgcg cagaacgggc gcattatttt gaagtcggca
     2881 gttaccacgc gttgaatcgc tatgccacgc tgcaattcac cggctggtac aagttgagca
     2941 acttcctgtc ggatgccggg cagttcggga cgacgccgct cttgaattat ttcgcgttcg
     3001 agcgcggctg gcagcgcggg atcgacggcg cgttgaagct gcaactcacc gacaacctga
     3061 cggcgcgcgg caacgtggcc tggggccaat gcaaaggcta tggcttgcag tcggggcatt
     3121 tcctgttgga ggcgaaggaa attgccgata tcaattcccg tggcggggtg ttctgcgatc
     3181 acatgcagac gctgaccagt tccgccgtcg tgacgtacaa attcctggaa cggacgacga
     3241 tgaccgggca gatgttgttc gcgtcgggat tgcggacggc cgagaacgag gaggcaaaga
     3301 ccaattcgac gcacagtccc tcgtatacca tctacaactt gtccattgcc catgtgtttc
     3361 cattgccgtg ggacggacag aaatttttgc tgggcttcga catcatcaat ctgttggatc
     3421 agaagtatta catcaaccag ggagagggca gtatcggtct gggtgtggct catgcgggga
     3481 tgccgagatc gttcttcttc cgtggccaat ggttcttcta ggtcagatgc cgaacaaggt
     3541 cgccagcagc agcgttctca gtcactcgtc tccctgcgac gtaccgcaag ggtacgcctc
     3601 agtcgccgag ttccctgcgg ccttgctgga caaccttgtt gggcatctgc ttcggactgt
     3661 gggaaaatgc ggccttgctg gatgacccgt ttgagcatcc gtttccgaca ggaaggttga
     3721 aggtgtgcgg cctagctgac aaccttgttg ggcatctgtt ccagactgtg agaaaatgtg
     3781 gccttgctgg atggcccgtg tgaacatcat catcgtgaaa ctggttggaa gacgatatga
     3841 cgaacatcat cgatggaatt cgatcactga cagtacccat ggtagtgctc ggcatgtggt
     3901 gcctgctgcc tgtatacgcc atcgcagtaa caggtgatga ggcgacgcat gaggcggatc
     3961 atgcgctgga tgcggagatc atcgagctgc ccgaagtgca tgtgcacgga ttgccgctga
     4021 acaaggatca gcaggtggga ccggtgccga aatcgacacc atggccggcc attccctcgt
     4081 cgctggaagg gaaacctctc gacgattgga tgaaggcgcg cttgctcgtg tcaaaagaag
     4141 cgcaggtgac ggtggtcgtg ttggaatcgg ccaaacatcg cgagctcacg attgccggca
     4201 tcatcgcgct caacaaatgg accttcgccc ctcagctcaa gggcgacgat ccagtcgacg
     4261 gggaactcac cgtgcgcatt cactttcgat cgcaatagat acgtctcgac aagcgagccg
     4321 caagggtccc ttgcgggacg agcacagtct acttcgggcg gcgaccttcg taaggcaaaa
     4381 acccatctgg aacaggatgc cggaagggtg tcgccccaaa attgccgctc cacgtgtccg
     4441 acttactgta atccccaccg ggcgagccga cctctactgc gacaacatac tgtcggtccc
     4501 tgacaatctg caggattgga ttgccgctgt cgggcgagcc tccaacccat acgccattgt
     4561 gtcgaacata gagatggcct cgcgtcaagt ccatggcgag tcctatcaca tctttgtcgc
     4621 gcagcccgcc cacattccga agatactgct tcactccgta tgccaattgc ccgccatgtg
     4681 aagtcagtcc gcctgactcg ttggccgtcg atcggatacc gacgttggtc cacgagatcg
     4741 ggaccgcgtt gtcggcgccg gcatgtacga tgaattcggc gtaccatctt ccgctgctgt
     4801 gcggcatcgt ggcgatgctt tcagtcgaag cgccgctcat gccatatccg acagtcagac
     4861 gatccggaga aatcatgttc cgcccgcgga atcgtgccga ggattcgctt tccgacttga
     4921 ataccactgg ttgcgtgatc ggcacctcga ttggagccgg aaactccagc gtcgtctttc
     4981 cgtcgatcac gatcgaatcg cctgtgtgga ggctctggac cgtcgcgggt tcgactccgg
     5041 ccatcgcgcg cacataggct ttaaaatcga tcaggccatc tcgggatgtc acgagggtcc
     5101 gaggaaacag gtcgtcccag ttgtcatcct cagtggatgc ggtattgacg ggaacggttt
     5161 tgtccagtcc tcgaatcgtt tgacggtaat agccgcggag aatcaccgac cctatgcgcg
     5221 cgccgggtac ggcggagatc ctccaatcga cagggttgta tgacatgaga aagagcgtga
     5281 tcggctcgcg cgtcttctct accgtgatgt gaatggttcc ctggggagtc tcgataggat
     5341 gagagtcagg gagatgggcc ttcccctcgt aaaccaccac ggcatgaagt gcgtgaacct
     5401 gtatcctatc gagcgcggtg gaggtcacag tttgcgccat gcggggctgc ttacccgctt
     5461 caagaatctg gcgcaatacc tgcgcgagag gcagagtggt gccattgtgg aactgaacaa
     5521 tgctgcgtcc gagaacggcc cgcatagccg ggtgaagaat ggcttcgcac acgaaagagt
     5581 ctctggtccc tcgtagagaa atctgcgcat catccgaatc cgtgcgggtt gcctccaaat
     5641 ccatggctgc tataccggga ccgattcgta ccattcccac gcactcggat cgtttctctc
     5701 ctgcccctct ggacaactca tagtgctgag cgccctgttt ctcattcgca gcatgaacga
     5761 caagcgcagc gtagccggcc agttgcgctg tcagtgcaag cgggaggaga agtccgaaaa
     5821 cgttccgaat catcatgatt gtgcctcaat ggtggcagga agggctgtac tctttccaaa
     5881 cagagatacc acgagagccg ctctccacca atcaggaccg gcttttgtgt gtgatggaca
     5941 gctactaccg aacggcgggc ttcttggtga ggtcgttgtg aaggcgatta ttctccgcgt
     6001 tgacgtcgat gccgcgaact gatggtggct tgtcgagatt cacgtattgg aaggtcccga
     6061 agggttgaat ctcatcatcg gtcggcaatt gctggcggtt ccagcctcct ccgagcgagc
     6121 ggatgagggc caccgaagtg cgaagcaatt cagccttgat ctgcaccgac tcgatccgcg
     6181 cggtcagcat ggcgacctgg gcgtaaatga gctcgaggct ggaagccaga ccgccctgat
     6241 agagctccat agtgagatct tgcgtcttga gggtcgctcc aacggcggca tcctgcctat
     6301 tggccgcaag ggtcagccgg ttggtcagac tcagattatt ctccacctcc cggaaggcgt
     6361 tgagtacggt cgatcggtac cgatcttctg tttcacgata ggcagaccag gactgctgca
     6421 attgcgcccg gcgataccca ccctggaaca gcggcagcga gacgccggag ccgtaggacc
     6481 agaaactgtt cgcgagcgag aacagattga aggcctcgtc ctcaaacccg cccccgagtc
     6541 gaaacgacac attgggataa aacgcggcgc gcgcaatccc gatggtgcga ttggcctgcg
     6601 ccatgcgccg ttccatggcg gcgatatccg gccggcgttc caataaggtt gacggaagtg
     6661 tttgggggat cgtgaaggtg gccattttga ggtcgttgac cggcgcgatc gtgaaggagg
     6721 ccggtgccac gttgagcaag atggcgatgg cttgttccaa cacctggcgt tgcccttgga
     6781 tttgggcacg cctcgtctcg gtgctgaaca acagggattc gacgcgagcc acgtcgagcg
     6841 ccgatgcaat ctggccgatg aactgggcgt tgacgagttc cagcgactgg gtgtacagcg
     6901 cgatcgattg ggtgtagatg gcatcctgcg cgtcgaggcc ccgcaacgca aaatagttgg
     6961 ccgccacctc cgcctgcagg ctcagccgtg cgagtccgaa gtcggcggcg cgctcttccg
     7021 cccggtagat ctctaccttt gtcgcgttgc gcagcgccga ccagaaatcc ggttcccagg
     7081 atgcgagccc gccgcccaca acgctcgatt cttccaatgg actatcgggc gcgcgaaaca
     7141 gccggtggag ggactgccga ttatcggtgg cgtcaaagcc caagccgaca cgaggcagat
     7201 attgcgatcg tgccttcatc atcacatcgc gggattgcac gaaccgttca gcggccgcct
     7261 gcaggtcagg attggccgtc aacgcttggg cttccaaccc gttcaggacg ggatctttga
     7321 agagagtcca ccagtcctga cgcaactcgc catcggacgg cttcgcttcg acgaatgggc
     7381 tcgacccatg ccatgaggcc gggaccacga attgagccgg ctcgtatgga ggggagagat
     7441 cgacagcggg aaaggtactg caggccgaca ggctgagcgc cagcaggagc gcggcggttc
     7501 gggcgaggtc tgtgaatcgg cgtgcgtccg ctcgttcacc tgatacgcat ggggctggcc
     7561 tggatcggaa acaggtcatt tcaacgccgg ttccttcgcg agtggcgtcg cggtgcccac
     7621 aagatcatac ccgggcgccg gtgtgacgac gcggaccttg tcgccttcca gcaaggcggc
     7681 gctcgggttg ttcacgatgc ggtcctgact ggaaatccct cctgacactt cgacggcatt
     7741 gtccatgagc ttgctcacgg tgatgggttt cagctgcaca cgatcgtcct ccgccaccac
     7801 ggccacttgc gtcccgtgct cctggaacac caacgcggtg gaaggaatag tgagcacgtt
     7861 ccggtcgacc ggcgcggtga gatggacctt ggcataggac cccggccaca acgcccggtc
     7921 ttcgttgtcg atcgtgaaga ccgtgacggc cgtgcgtgtg ctgacatcga acccgcgggc
     7981 gaccgtcagg aatttcgcgg tgaaatgacg atcgggtaat tgcggtaccg tcacgtcagc
     8041 cgtcagtccc ggcttgagaa acgctccgaa ggctgccggt acgttgacga atagccgcag
     8101 catgctgaca tcggcgacgg taaacaaatt ggtgatggag ctccggttgc tgatgttgcc
     8161 ttctttattg atgtagtcgc cgacattgat gttgcggacg gtcaccactc cgtcataggg
     8221 cgcgacgatg gttttgaact ggatcagcgc ttcgaaattc ttcacgttct gctccgctgc
     8281 cttgaccctg gcggcttcgg ccttggcatt ggcttcctgc acggagatgg attgttcgga
     8341 gaccgcatgg tttttgcgca gcgcgaccca gcgtttcgcc gtcaagtcgg cgagggcata
     8401 tttggcttgt tctgcggcga gatccgcctt cgcctgggca tattgcgcat ccagggcagg
     8461 cgcgttgatt tcagcgagga tgtcgccctt ttgcaccagg gcgccgtagt ccttgtacca
     8521 catcttgacg tagccggaga cctgcgcgta gatcggcgct tcgaaccagg cctggatatt
     8581 accgggcagg gtgatcgttt cggtcggcgg caccggcttg gggtaggtga tggccactgt
     8641 ggggatcgtg tcctccagcg tgtgcttgcg caaggttgtg gcgtcgacat tgctctcgta
     8701 gatgcgataa ctgagataga acagaagcag gacaataccg agtaggactc cagggcgtgg
     8761 agagagacgc ttcagcatca gagttgctcc tttgcgggaa cgcttcgccc gtcatacaga
     8821 atggcataga cgcacggcac gaaaaacaag gtgaagatcg tggccacgag caggccgccg
     8881 atcacggcac ggccgagcgg ggcattctga gaatatcctg tcgccatggg gaccatgccg
     8941 aagatcatgg ccgaagcggt catgagtacc gggcggaagc gggtcgtgcc ggcttcaatg
     9001 gccgcccgca gcgcttcgcc atgcgtttcg agccgttcgc gcgcgtagga gacgaccaga
     9061 atggaattgg ccgtcgctgt tcccatggtc atgatggctc ccgtcagcgc cggttccgag
     9121 aggcgcgtat gcgtcaggaa caaggcccac gcgataccgg ccaacgcacc aggcaaggcg
     9181 gtgatgatga tgaacggatc gagccaggac tgaaagttga cgacaatcag caaatagacc
     9241 agcacgatcg cggccagtag tccgaagatc aactcgaaat acgcgtcgtg catcagcgaa
     9301 gcctggccat ggatctcgat ggcggcgctg cgcggcaact cgtgctccat gctcttggcg
     9361 acggtttcga catccgccaa tacgccgccg aggtcgcgcc cttccgtgcc aacgtagata
     9421 tcgaacagcg gcatgatgtt cgcgtgggtg atcacgcccg gtgtgccctc ggccgagagg
     9481 tcggcgagat tgccgagcaa ttgcacatca tgattgttgt ccgacacatc attcgaaggt
     9541 tcaacgggaa tggttctgag gctgttaacg ctattgacct gcgcttgcgg cgtatacacg
     9601 ttgatcagat aagacatgcc ggtcttggga tcgagccaat acacctggtc gatctgttgg
     9661 ctgccggcgg tcgtcatcag gaggttggac gccatttctt tttgagtccg gttgacggcc
     9721 agaccgaagg tgcggttgcc ttcgaccatg agcgtcggcg tccgcatggt ctgttggatg
     9781 accacgtcgg tcgcgccggg gatctggcgt agtctgccgg ccagtttgcg ggtgaactca
     9841 tagttgggat gcatgtccgg acccttgatc tgaacgtcga tcggggccgg tgcgccgaag
     9901 ttcaggatct tggcagtcag gtcggacggc tggaacgtaa actctgtacc agggtaacgc
     9961 tccgtcaacc ctttgcggag aatgcgccgg tactcccaca ccggcgactt ttcatccctc
    10021 aacagaatcg tgaggtcgca atcctgcgat ccgatggtcg gcgtcggaat gaacgccaag
    10081 ttatgcgctc ccaccggtaa gccacaattg ctcacgatgt tttccacctc accggccagc
    10141 agctcttcga cactgttgga gaccagcgtc gcgatacgtc cggatacctc gatgcgtgtt
    10201 ccgagcgggg cccgcatatg catctgaatg acaccggatc tgatttcggg aaagtagtcg
    10261 cggccgagaa agaagaagag tgacagcgag gccacggcga tcacgaggca gaccgtgaca
    10321 aacgcccggc gccgggccat ggcccgttcg agcagcagcc catagcgctc acggaaccgg
    10381 ttgaacccgc gttcgaaccc ttgttgaaac cgaacgaaga tattgcctga gacaaccgga
    10441 ccgggctgtt cagcaggttc aagcggcttc gacatggtgc cccttcatca tgtatttggc
    10501 catggtcggc actaaggtgc gcgacaggat gaaggaagcc agcatcgcaa tgatgatcgc
    10561 ttccgccatg ggtttgaaca ggtagccggc gacgccgccg agttcgaaca gcggaatcca
    10621 gacaatcgca atgcagaggg tggcgacgaa tgtcggcacc acgatttgat tcgcggcatc
    10681 gacgatggcc tgctcgagcg gcttgcccat ttcgagatgc cggtcgatat tctcgatcat
    10741 cacggtggcg tcatcgacga ggatgccgac ggccagtgcc aatccgccta aggtcatgac
    10801 gttgatcgtc tcatcgagcc agtgcaaacc gatgagggcg gtgaggatgg agagaggaat
    10861 tgacgtccag acgatcaccg tggcccgcca tgatccgagc aacagcagca caatcaggcc
    10921 gaccagtgcg cctgcggttg ccatttcatg cagcacatcg gcaatcgaat ccttcacgaa
    10981 ggtggaggcg tcgtcgagca gtttgatctc gacgccctcg ggagagatct gctccgcgcg
    11041 cgggatcatc ttcttgatcc cattgaccac gtcgagggtc gaggcctccg tgctcttcat
    11101 cgcaacgatg ataactgtct gtttgccttt caccagtacc gcgttctgct gcacccggcc
    11161 catgaggcgg acagtggcca catcgcgcaa atagatgaag gcgttgtctt cccgcttgac
    11221 cgggatatcg ctgaaatgtt cgatctgcat cggggaagca ttggtctgga cgatccaatc
    11281 ggtttgcttg attttgatat caccggacgg cagcaccaga tactgctgca tgagggcatt
    11341 gtgaatatcg gccggcgtca gattgcgggc aagcagcttt tgctggtcga gattgaccat
    11401 gacctgcatg tcctgaccgc cataggggtg ggggaggacg attcccggca cggtcacgag
    11461 taagggccgg attcgcatgt aggccagatt gtagagctcc gccggggtca gccggtcgga
    11521 actgatctgc agcatcgcca cagggatgga agagggcgcg agacgcatga ccatgggtgg
    11581 cgagatatcc ggtggcagcg ccttgacgac ggtctgcgca atagccgtga tatccgcctc
    11641 ggctctcccc acatccactc cgtcctggag gaaaatgttg gtgatgctgc tgccgtaata
    11701 cgagtgactg tgaatgtatt tgatgccctc caccgtcgaa gtgagaaagc gctcgaagag
    11761 ataggtgatg cgtccttcga cctgctgcgg cagcaggccg gcatatgccc acaccaccga
    11821 ggtgacgggg atcgtgatat tgggaaacac gtcggtcggc atgtggagca ccgtgatgct
    11881 accgagcagc acgatgagaa tggacatcac cacgaaggtg tagggacggc ggagggcaat
    11941 gaggacgatt tcattcatac agcaagtcct cgtcctgcaa tacggggatt gcagatctat
    12001 gattagaaca cgaagagcag tgtgcgattc ttgatgacgg gatagagcaa ggttcttgcc
    12061 gacctgcgcc tgttgtgacg acggacgaca atggtcgtgt attcgcacgt tttggaggga
    12121 gcgatcactg aatttgattg cgtcgtcttg cgacaacggg aaggcaaatt cttgaagggg
    12181 cattatcgca ctgtgcgcac agtgcaaagt ctcacggttt tgccagacga gaaatctcag
    12241 cggtcatgca aaaagctccg tcatttcaca agaacctcaa caattgttcc ggctttcgga
    12301 gatcgtggga cgacggatgc ggctggtact aatcttgcga caatctcgtc gtgtgcggaa
    12361 gctggcgtat ggcaatgttc gcgaagacct gcgcagaggg aacacggggg aggttgacgt
    12421 aatgaagaca ttccggagat tcagcaaggc gctcgtaatg gcagtcgggc ttgtgggagg
    12481 actggccatc ggcgagcctg cagaggcaga aaatctgacg atcggcgcgg cctatagtct
    12541 gaaggcggcc tttcaggaag tggtgcccat gttcgaaagt gagttcgggg ccaccgtcaa
    12601 cgtcgtgtac ggttcctcgc aaaccctccg ccgtgaagtc gagagcggag cgcccgtgga
    12661 tgtgttgcta tccgcggtgg aggatcttga gaaattgcag aaaaagggat tgaccctcaa
    12721 cggcgggccc gaggtctatg cgcaaacgtc gttggtgttc gtcatgtcgg cggcgtcgca
    12781 ggccatgccg atttcttttc acgacctgtt gtctgagcga agaaccaggg ttgcaatcgg
    12841 ggcgtttgaa agtgctgtcg ccggccctat taccgcacgg gctcttcgag cggttgatcc
    12901 ttcctataaa gaccggttcc gtctgatctc ggccacgcat cacgacgaag tcattgagat
    12961 gatccgacgg gaagaagcag agatggggct ggtgtaccgc gtagatgcga taaacaacag
    13021 cggacaggtg cgtattatcg atgagatgcc ggggggtacc tatacgccgg tccggttcgg
    13081 gcaggcgata gtgtggacct gccgcgatga gtcacgcacg gctgccgaac aattcaccga
    13141 tttcttcatg agtccccgga ttcaaaagct tctgctcaaa tatggattcg agccagcggc
    13201 atcgcatgtg ggcgagaata aggtggcgcg cactgcacca aaagttcggg tcaattaacc
    13261 cgcctcaatg cgggttctcg actccgctca actgacctgc cggccgtgcc acgtccattc
    13321 cttcatcgtg cctgatcagc ttgcgtccgg atagcatgcg caggccgacg taaaacacgg
    13381 gtgtcagaaa caagccgaac agagtcacgc cgatcatgcc ggcgaatacg gtgatgccgg
    13441 tggcggaacg cacttccgcc ccagcgccat gtgacagcac gagtggaacc gtgccggcga
    13501 tgaaggcgac cgacgtcatc acgatagggc gcagccggag gcggcaggct tcgagggctg
    13561 cctcaacaat gcccttgccc tgtaattcga gctcgcgcgc gaattcgacg atcaggatcg
    13621 cgttcttgca cgccagaccc attaacacca ccaggccgac ctgcacaaac gtattgttgt
    13681 cgcccccggt gagtttgacg ccggccagcg cgcacagcat gcacatcggc acgatcagga
    13741 tcaccgcgag cggcagggtc caggattcat acagagcggc gagtacgagg aaggccagca
    13801 aaatggcgat gggaaacacc agcagcgccg ccttgccttg cgacgcttcc tgaaagctca
    13861 aatcggtcca ttcgatggtc atgccgttcg gcagcacctt cccggcgatg tcgcgaatcg
    13921 tgtccatcgc ttgcgccgag gaaaacttgg tgggatcagc ctctcccatg aaatcggcgg
    13981 cagggtagcc gttgtagcgc agcaccggat caggaccgta cgtctgactg aacttcacca
    14041 tcgacccgat cggaaccatc tcgccgcggg cattgcgcgt tttgagattg gaaatgtctt
    14101 cgacctttcc gcgaaaatcg ccgtccgcct gcgcatacac gcgccaggtg cggccgaaca
    14161 ggttgaagtc gttcacatag gctgaaccga ggtagatctg catcgtggcg aaaagatccg
    14221 tcaacgcaat gccctgtgtc ttggtcttga cgcggtccac ctcggcgtcg agctgcggca
    14281 cattggcctg ataaccggag atcgggtagc ccatacccgg tgtctgcatg acggctccct
    14341 gcaggccgcc gaccgcattt tgcagcgccc cgaagcccag tccagcccgg tcttcgacga
    14401 agagtccata ccccgcgccg ttgccgagtc cgagaatcgg cggcggcatc aacacgaagg
    14461 tgatgccttc cttgatggcg gagatctttt gattcatctc ctcgctgatt tccttggcgc
    14521 tgcggtggcg ctcgtcgaac ggcttcaaga tgagaaaggc gatgccgtaa ttcggcgtgt
    14581 tcgtaaactg caacggattc aggccggtca tggctaccac atgggcgatg ccgtccacgg
    14641 tcttgctgat cgcgaccacc tgccgtaaca ccgcatccgt acggtcgagc gaggcgcctt
    14701 ccggcagttt cactccggcc atcagataca acttatcctg ggtgggaatg aagccgcgcg
    14761 gtaccgcctg gaagagcatg cctgtgacga tcaagagcaa tgcgtagacg gcaaagaccg
    14821 aaccacgatg tttcaacgtg cgcgagacgg tgccttgata cccgttggaa ctggccttga
    14881 aaaagcgatt gaacggccgg aacacccagc cgaatagacg ttcgatcaag cgcgaaaggg
    14941 cgtccttcgg tgtgccgtgg cttttgagca gttttgctgc gagggccggg gaaagggtca
    15001 gggaattgat ggccgagatg accgtcgaaa tggcgatcgt cacggcgaac tgtttgtaga
    15061 actgcccggt gacgccgctc agaaaggcca tcggcacaaa cacggcacac aagacgagcg
    15121 cgatcgcgac gatcgggccc gacacttcct gcatcgcctg gtgggccgcc tggagtgggg
    15181 tgcgtccttc ctcgatattg cgttcgacgt tttccaccac cacgatcgcg tcatccacca
    15241 cgatgccgat ggcgaggaca agcccgaaga gcgtgagtgt gttgatggag aaaccgaaga
    15301 ggtacagcgc agcgaacgtg ccgaccaccg acaccggcac ggcgatcagc ggaatgatcg
    15361 aggcacgcca ggtttgcagg aacaggatga cgacgaggac gacgagcaga atcgcttcca
    15421 tgagcgtctg gaccacggcc tggattgaat cacgcacgaa taccgtcgtg tcgtagtccg
    15481 agcggtaggt gaggccgggg gggaagcgtg tcttgagttc ttccattttg gcaatgacgg
    15541 cgtcgcggac ggtcagcgcg tttgcgccgg gcgcctggaa gataccgatg ggcggtgcgt
    15601 cctgattgtc gagttgtccg cgcaacgtat agtcgttggc gcccagttcg atgcgcgcca
    15661 cgtcggaaag acggacgact tccccgcccg cgccgatttt cagcacgaca ttgccgaact
    15721 cctgggccgt gcgcaggcgg ccttgggcat tgatggaaat gagaaagtcg gtgtctttgg
    15781 cgatcggttc cgcgccgagc tgcccggccg agacctgaat gttttgctcc cgcacggcgg
    15841 cgacgacgtc actggcggtc attccgcgcg acgcgatctt gtcagggttg agccagatac
    15901 gcattgcata gtcgccgctg ccgaaaatct gcacctggcc gacaccgggc aaacgcgcca
    15961 gttcatcttt tattttgatg ttggcgtagt tgcgcaggta gagcgcgtcg tatttgccct
    16021 ccggtgaaag gagctgaacc atcactagga aggtcggcga ctgtttctgc gtcgtaacgc
    16081 ccaggctgac cacttccgac gggagccgtg aaagcgcctg actcacacgg ttttgcacct
    16141 gcacttgggc cgcatccgga tccgtaccgg gacggaaggt gatcgtcatc tgcaacacgc
    16201 catcggagcc ggcgaccgat ttcatgtaca tcatgttctc gacgccgttg atctgttcct
    16261 ccagcggcgt ggacacggtt tcggcgatca ccttgggatt ggctcccggg tagatggcgc
    16321 gcacgatgac ggccggcggg acgacctcgg ggtactcgct gatcggaaga ataggaatgg
    16381 cgatcaaccc ggcggcgaag atcacaatcg acagcaccgc ggcgaagatc ggccgatcga
    16441 tgaaaaattt cgaaaagtcc atagccggcg ctccctactt cccggccatg gcttgagggg
    16501 cggcgggcgc cgacggcttg tccatcggta cttcggccgg ggtcaccggc atgccggggt
    16561 agaaaacttt ttgcagcccg accacgacaa tcctgtcatc cggcgcgaga ccggattgca
    16621 ccacgcg
//
LOCUS       DAOQPD010000088        16527 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1754_length_16527_cov_17.563623, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000088 DAOQPD010000000
VERSION     DAOQPD010000088.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 16527)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 16527)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16527
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1754_length_16527_cov_17.563623"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..790)
                     /locus_tag="PK063_15915"
     CDS             complement(<1..790)
                     /locus_tag="PK063_15915"
                     /inference="COORDINATES: protein motif:HMM:NF019530.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraG N-terminal
                     domain-containing protein"
                     /protein_id="HMZ98587.1"
                     /translation="MWTIYTFGNGDVLTQILLGIRIMMTTGRFESLMELALLVFAMFG
                     LVYFVFNRRFLVPLVVGAFFILFVSVRITVDVSVEDQVNPDVPDQIVNSVPLAIALPA
                     YLSGQVGYYTTQLVEASFPMPVQYTQGQASFNRPLFDLQKVLNARLQDSDLARNTDSY
                     FMMCVFREVGLLQKNLGTLMNSPNLLNDIGATNNALTALGYTGGTLEAAPRVCPDFYS
                     SLILPAYTTGQPDYEGAMRHLRTQLQLDPATGDEEGLTEDIRANL"
     gene            complement(835..2169)
                     /locus_tag="PK063_15920"
     CDS             complement(835..2169)
                     /locus_tag="PK063_15920"
                     /inference="COORDINATES: protein motif:HMM:NF017892.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraH"
                     /protein_id="HMZ98588.1"
                     /translation="MRSKLILVGVCMWAVLVWPPLVQAQSMNDALTNMFTSWGVGITS
                     PPGAYESQSRGYFSGGGVSVRLWQDPMRLWSIAPPRLSVGCQGIDVYLGSFSYGKLDR
                     YVQLLQQIGTGAVLGYAFQLAMKAICEDCADVLNKIEAAARALNAAGRIQPCQTGIEL
                     GKALAGNEASKQKLASRFGDAWQKMKEAGGAIGDVFEDRDTVKNQSNADAASALKGTE
                     YDVTGNLVWDVLTQAGLDQNLIVMVMSVTGTVIVGNDGDVQTRDPTMTFEQLVDSHLG
                     DVVKVFNCGGDSECLNPTITDATDIEGFESRVYTSMSNLIEDLYSGSAISATDQQIIN
                     MTPVPILTMLADYGRPRDVGNQIARLSSEVVAADMGYQWVKWAATETSRNVSYIQKVK
                     PEWPGNLQDFQGRLHQILRGASESLAKRQRMVNNINQLMQLTKTQGEMRSLR"
     gene            complement(2180..3082)
                     /locus_tag="PK063_15925"
     CDS             complement(2180..3082)
                     /locus_tag="PK063_15925"
                     /inference="COORDINATES: protein motif:HMM:NF025105.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
                     /protein_id="HMZ98589.1"
                     /translation="METTKLLHALAWYCVTFCSVGGVSSAVLAAEPPGSQTFIDHPRQ
                     GWFSYQDPSAEAEEDAEESPVPVTMDSLPPEAWLDPSKYRTLFKGLSVEGVKLNALPM
                     TVLRELVSAKKERALDHPSVENVTTYIKVQKEAYDRSQRFTDAWQIAMYTDPKLDYAS
                     QHPTSTYGHSVEAEIKRNTEEQLLAGTADRVGLFFFFTSTCPFCQEQSKVLKVFADTY
                     GLTVKPVSLDGVGLPEYPQPATNNGMAENVGVHMVPMIYLAIPEENFLKPLGAGLMTN
                     ADLRERLLVLLRNRGLLGERRSQG"
     gene            complement(3052..4140)
                     /locus_tag="PK063_15930"
     CDS             complement(3052..4140)
                     /locus_tag="PK063_15930"
                     /inference="COORDINATES: protein motif:HMM:NF018536.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraU family protein"
                     /protein_id="HMZ98590.1"
                     /translation="MNKLSKRRIQHMLLLVCLSCVLIGVVTLWPSGSAEAVCTTGTNV
                     LANSLATTCWECMFPISLSGVTVFNLGEDFTEPAIGPGHAPFPPQLCGCVCLGPICIP
                     GLPLGIWEPKNLVEAVHDPLCFPTLGVSLAGGFSYIGRGMATTQMDSELNYAFFHVHY
                     FVFPLWAIVGIGMDILCLNPTGIADEIDLAYASEIDPLWDDDLISLILFPEALVLANP
                     VALAACAADSVAAAVGFPIDPLFWCAGSFGFMYPPTGHVSGADGDLKPAALSMTRLLA
                     KLARAGTEFWTSANGPLLCEDIPTALIVKSQYKFQLLWPIPNTGLPPPCCQPLGRTLM
                     MWGLGKIVPAVGEDFVWLLWKRQNCCML"
     gene            complement(4133..5209)
                     /locus_tag="PK063_15935"
     CDS             complement(4133..5209)
                     /locus_tag="PK063_15935"
                     /inference="COORDINATES: protein motif:HMM:NF021209.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC family F-type conjugative pilus assembly
                     protein"
                     /protein_id="HMZ98591.1"
                     /translation="MAQDIARYSRQALRHGRPQESPKEVRRDGVYLLLSFSLPNDTLK
                     DYLREAKLLGAKVLLRGLVQDSFKVTQERIKHLLFTGDHPDDSLLVGIGIDPVIYRTV
                     GAGEVPALVFVKDEKFLVASGGASVAHLLTLLSKEQAGVMPWIEWFERRHRGFLQGGP
                     TEEAPPQVPTIGQSVKVQGDARGADIAERDMIDVMKERVAKADWPDIQRRSGDALKRQ
                     FAKGPGLALPHAEEARVVLVDPTVEYPEDIKDPTTNTVLIKSGTKINPFDKVRWIRTL
                     VFFDGTSSSQVGWVQQYLKEHDPKFVKLIISDGDVQKVMEQLHQRVYWANPLLVSRMG
                     VGAVPSIVSQLGRHLRVEEVAIHE"
     gene            complement(5384..5962)
                     /gene="lepB"
                     /locus_tag="PK063_15940"
     CDS             complement(5384..5962)
                     /gene="lepB"
                     /locus_tag="PK063_15940"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: protein motif:HMM:NF021981.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HMZ98592.1"
                     /translation="MKLFNALSLLNVLKRAPTILDWLDRHRWTHVGLMLFCGAIITAG
                     VIAPWYEVAARMSGSWPHHNFFLIQKGQPVGRGDLVAFIMRRDYVERVQPGHLHRDYA
                     DVGNRWMKRIVGVPGDHIVIKEDEVYINGQSVGRGFGIDRYGQRIDLASLPEVIPEGE
                     YYVALPHPRSFDSRYYGLIRKADILGTVTPLI"
     gene            complement(5892..8405)
                     /gene="traC"
                     /locus_tag="PK063_15945"
     CDS             complement(5892..8405)
                     /gene="traC"
                     /locus_tag="PK063_15945"
                     /inference="COORDINATES: protein motif:HMM:TIGR02746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein TraC"
                     /protein_id="HMZ98593.1"
                     /translation="MSTILEWKVKQLVDRTAISDWLPYEAWDDTNQVYRLDDGRIGVV
                     FSSKPLLGLSEESIQKLTNLFESDLPIGTTFQFMLHASPIIEPYLDNHVILAQRGQAG
                     ERYVADARKTAEFYLHARDTQLTSNPPLRPRDFTVYVSVAFPTQETTAQGWEDERIHQ
                     AVSGIEGQLNTLGLLPERVGPLQLLSLLHVLLNPGHSWESRPPAYSDQLPIRDQAVRL
                     DTKATLRTKMIELDGKFLKTLTVQSWPVQWHGGNNRELIGSLIRFTDQITCPFFLTLN
                     VLKFDQVKAKGKLRKKHVIINQQASGFLLGLIPSLKFKLDHFNGVQAQLENGRQLIGS
                     YFQVVLYGDTPRHVEEQTGALRALYRAKDINLQEDHFIGWKILMTGLPLGLPSDDKAL
                     IDGLRRMKTYHTEVPAHICPIVADWKGGGAPVVLLTSRSGQLITMDVFANQQTNYNMA
                     IAATSGAGKSFFMNNWIKSYLGIGGQVWVIDAGFSYVKLVELLKGQYIQYGANAQRLC
                     FNPFSKLVHWGSNAGGVDDPSDRADELATLKALHAQMASPSRPLSDVELSFIEEAIMR
                     VLEGEGCEGCPDSVHKVLKSMTDPRARDLARVLASYAKGGMYSHLFNGANNVNFENDF
                     VVLELDGLNEQKQLRSVILLQMQMNIQAVMYKKENRGRRKFVILDEAWDLLSQGGNTA
                     AFFETGARRVRKSGGSMITITQGINDYYDKMRDVGRYLLENAEFVGLLKQKTESIAAF
                     RNNGRIVLSEMEYRLLSSVTKTTEYSEIFMITPFGRGICRLTVPRETQLLFTTNPDEL
                     SMIDRVRKEGPKELSIDEAIQCIIAAERAQAGADNPRLA"
     gene            complement(8430..9161)
                     /locus_tag="PK063_15950"
     CDS             complement(8430..9161)
                     /locus_tag="PK063_15950"
                     /inference="COORDINATES: protein motif:HMM:NF021212.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraV family lipoprotein"
                     /protein_id="HMZ98594.1"
                     /translation="MMSGYIRRYITRGGSWYGLGSGVAMGLSVLLAGCGGYESNFSCK
                     GYPDQATCESVSEAYEKRFSAGQKVTQYTKDQKGVGQDTSSSSGPGQVTPPMIFSGKP
                     DSAIGKPVITPVSALRVTVFPWKDTKKRLHDQSRHYLIVDEPDFIFGHMAQGVSAGSS
                     SGHGKDLYPRMGRMVEKRDGKRTPSGNAAANAMTENVPEVGQRSAPMSVNPLGSGGIM
                     PQGFPQLPQTGASNYLTDDGPLPPQ"
     gene            complement(9200..9877)
                     /locus_tag="PK063_15955"
     CDS             complement(9200..9877)
                     /locus_tag="PK063_15955"
                     /inference="COORDINATES: protein motif:HMM:NF024498.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbC family protein"
                     /protein_id="HMZ98595.1"
                     /translation="MRPIKTVIEQKFPGMKVLRVSKTEIPGWLLVESDSDRVENYMYV
                     HESGRYVLSGALFDIQMGRNVTQEYVRDRQQALLAGMDTSKTILLSPMQSKLERPVLV
                     FDDPDCRFCQQFHPEVQKLVEAGVPVAVVLYPLVRTHPDAYRKSVAIWCAPDQAEALG
                     RALMSKPVMGEVGACSHPIDENIKLGKRLGVNSTPMVFLPNGQSFAGYRPASEVLALL
                     QIEAQQK"
     gene            complement(10006..11292)
                     /locus_tag="PK063_15960"
     CDS             complement(10006..11292)
                     /locus_tag="PK063_15960"
                     /inference="COORDINATES: protein motif:HMM:NF015688.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbI/VirB10 family protein"
                     /protein_id="HMZ98596.1"
                     /translation="MASIKPTESAILNPGDPIRPEKPAPSKLLAGVVLVGGFIVLSMV
                     LQQFRGNQPGIVRGKSPAKTVSINREETDKEIYMKDAGARIEALEQQRDQMRRLLEQD
                     GRDKTEIKTQLSDLQKRIESVARSGGVVSAGTKSGALPPLPPPLSANPVGGGSATPVS
                     TMPVPKGPIPVQSTPKPAGGTLPAPGAGGGLTEGFQVFRPEIVPGAKKNEKKLWLNTG
                     TIIPVKLLSGMDAPARSTGAQGGGASANSPYPVLMMVRDIMKLPNEARIDAKDCFLVG
                     EGLGDLSSERVMIRGNALSCVKKNGEAVDIELKGFVSGEDGKQGMRGRVVLKEGALLG
                     RTLLAGFVSGISRAFMPYQSGFFVAQSPSQAFNLPPAGPVAMSGMAGGAGRAAELLAR
                     HYSMMAASIFPVIEIDAQREVDFIVGTGRELEGFFQ"
     gene            complement(11313..12086)
                     /locus_tag="PK063_15965"
     CDS             complement(11313..12086)
                     /locus_tag="PK063_15965"
                     /inference="COORDINATES: protein motif:HMM:NF018311.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system secretin
                     TraK"
                     /protein_id="HMZ98597.1"
                     /translation="MTSSVYRDSKHRAMAMCVLGLLLFLSWARSVGAAVVVGDEGATS
                     LTLSGRDLNVLTFPAPITMATSSRADLKAKPEGRNLIVQVKTGPADLVVMAGEQTYVF
                     EVGVSVSLGAQTISIEDRRVGTVVYDTDPARQAADYVDGLLETLQMAARGALPKGYRQ
                     TSIAEERYPKWLELKVVQGIEYRGPKYRVIVYRLVNTAGHKYTLREQEFLTGVQKAIA
                     LNREVVESGEEVVVYLLDDAPPEPPKPKPEPKVDPDAKS"
     gene            complement(12097..12678)
                     /locus_tag="PK063_15970"
     CDS             complement(12097..12678)
                     /locus_tag="PK063_15970"
                     /inference="COORDINATES: protein motif:HMM:NF017152.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraE/TraK family type IV conjugative transfer
                     system protein"
                     /protein_id="HMZ98598.1"
                     /translation="MTIELWKSKLHNAQVLNLVFAALATVLAVALVANGFFRQNVAVH
                     VVPINPTQEYWANAMGGDEYYKKSIAMAMLPWIANVTPASVEFHHRQLLQWVPSSHYG
                     LMSESLGAEAVYVKTNNLSRVFFVTASRVDGDVAVFEGIERRFVGKSEIREEEREYRI
                     SMRWDQGRPWVVGLSAAHLDRSRQDSQSDPAKG"
     gene            complement(12684..12965)
                     /gene="traL"
                     /locus_tag="PK063_15975"
     CDS             complement(12684..12965)
                     /gene="traL"
                     /locus_tag="PK063_15975"
                     /inference="COORDINATES: protein motif:HMM:NF018836.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraL"
                     /protein_id="HMZ98599.1"
                     /translation="MNGTFIPRYLDSLPQIFWWEIDELAVLFVCIFLGIVTKFLTYLI
                     VVGIVSTLILSKMKNGKSEGFLFHWAYWSGVPTFQLTGSPHGTTREMME"
     gene            complement(13044..13364)
                     /locus_tag="PK063_15980"
     CDS             complement(13044..13364)
                     /locus_tag="PK063_15980"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98600.1"
                     /translation="MGNVLKRVTGEMWRMSLLLGLMVLASFVVLAVPAFAGADATFGP
                     LVTLLTNYMQGSLGTLLALVAGAIGLGSAMAGRWAGMFTGFGVAAAAFYIPNIIPTIT
                     TGLM"
     gene            complement(14697..15485)
                     /locus_tag="PK063_15985"
     CDS             complement(14697..15485)
                     /locus_tag="PK063_15985"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98601.1"
                     /translation="MPSSAVGGLMLEYAADWQESLVQRAEQCARSITYVAGELIRERF
                     RLGGIVVEALERSQHGDAVVVKMAERMSAAVGKCIRPHMLYESARIYNAFGGQWERIE
                     ALRAQLSFPLSYSYLVRFCLPALTMDSAWNAEQVTYSNDSELRGFESAVLRIEARVQA
                     HRTRQQEGGKERSTDLETEGFVGACTQSAEFQEMAVRTIVRRLDVLCEALEGKAQQRG
                     VELEALRESQEAIARIASRMATLGTLIHAPVMHAVIPDNNTSVL"
     gene            complement(15475..16287)
                     /locus_tag="PK063_15990"
     CDS             complement(15475..16287)
                     /locus_tag="PK063_15990"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98602.1"
                     /translation="MRGGRKWLLAVAGALGLVCLGGNVVMALSPVNISPGYPTSLDDA
                     YPVPTDQVVIQSAIRPDITRNDSGSESGRFRATHDIRYGATENMELTVSGTSLRGPLN
                     PGTMDDPRSIQLGILARFRKQAEERELLPSISVRVLGEVPYAGDRTNPGLRGALVTSW
                     NLGNRWWLHGNLGYEVVPSFQPGHWVPHRSSIIFVNLGFVKALDESSAIVGGLRFQED
                     PLNSKKQVASPELGYVLALDKHWLFSLSASRDFLGSVGQAAFRGSVGVIYAF"
BASE COUNT         3733 a         5213 c         4034 g         3547 t
ORIGIN      
        1 agagattcgc ccggatgtcc tcagtgagcc cttcctcatc gccggtggcc ggatcaagct
       61 gcaactgtgt acgcaaatgc cgcatcgccc cttcgtagtc aggctgcccc gtggtatacg
      121 caggaaggat gagagaacta tagaagtcgg gacacacccg cggggccgct tccaacgtcc
      181 cacctgtata tccgagtgcc gtgagtgcgt tattcgtagc cccgatatca ttgagcagat
      241 tcggagaatt catcagcgta ccgaggttct tctggagcag gcccacctcc cgaaacacac
      301 acatcataaa atatgaatcg gtattgcggg ccagatccga gtcttgcaat ctcgcattga
      361 ggactttttg cagatcgaat agcgggcgat tgaatgacgc ttgtccctgg gtatattgca
      421 cgggcatcgg aaacgacgct tcgacaagct gagtcgtgta gtaccctact tgccccgaga
      481 ggtatgccgg taacgcgatc gccagcggca cactgttcac aatttgatcc ggcacatcgg
      541 gattgacttg gtcttccacg gacacgtcga ccgtgattcg gacacttaca aagagaatga
      601 aaaaggcccc gacgaccagc gggaccaaga agcgccgatt gaacacaaaa tacacgagtc
      661 cgaacatcgc gaagacaaga agtgcgagct ccatcaggct ttcgaagcgt ccggtggtca
      721 tcatgatccg gatgcccagc agaatctgcg tcagcacatc gccgttgcca aacgtataga
      781 tcgtccacat gatgcgctat cctctccctc acatcgcaga cagacttact ccgactaccg
      841 cagcgatcgc atttcgccct gcgtcttcgt caactgcata agctggttga tgttattcac
      901 catacgttgc cgcttcgcga gactctcact agcccccctt aggatctgat gcagccgccc
      961 ctgaaagtct tgcagattgc ctggccactc gggtttgacc ttttggatat agctaacgtt
     1021 cctggacgtt tcggtggccg cccacttcac ccattgatac cccatgtccg cagcgaccac
     1081 ttctgaagac aatcgcgcaa tctgattgcc gacatcccgt ggacgcccat aatcggcgag
     1141 catggtcaga atggggaccg gggtcatgtt gatgatttgc tgatctgtcg cgctgatagc
     1201 tgagccggag tagaggtctt cgatcaggtt actcatggac gtatacacgc gactctcgaa
     1261 tccttcgata tcggtcgcgt cagtaatcgt ggggttcaaa cattccgagt cgcccccaca
     1321 attaaacact ttcaccacgt cgcccagatg actatcgacc agctgttcga aggtcatcgt
     1381 cggatcgcgg gtttgaacat cgccatcgtt cccgactata acggtcccgg tgaccgacat
     1441 caccatgacg atgagattct gatccaggcc agcctgcgtc aggacatccc acaccagatt
     1501 gccagtgaca tcgtattccg tgcctttcaa tgctgaggcc gcatccgcat tcgactggtt
     1561 cttgacggta tcccggtctt caaacacgtc tccaatggcg ccgcccgctt ccttcatctt
     1621 ctgccaagca tcgccgaatc gactcgcgag cttttgtttg gaggcttcgt tcccggctag
     1681 cgctttgccc aattcaatcc ctgtttgaca gggttggatc cgtcccgcag cattgagcgc
     1741 tctcgcagcc gcttcaatct tgttgagcac gtccgcgcag tcttcacaaa tggctttcat
     1801 cgccagctgg aaagcgtacc ccaagacggc accggtcccg atttgctgca gcaattggac
     1861 gtaccgatct agtttgccgt aggaaaacga gcccaggtaa acgtcgatgc cctggcagcc
     1921 cacgctcaat cgcggcgggg caatcgacca caaccgcatc gggtcctgcc acaaacggac
     1981 cgagaccccg ccgccgctga agtagcctcg actttgactt tcgtaggcac ctggaggact
     2041 cgtgatcccg acaccccacg acgtgaacat gttcgtaagg gcatcattca tcgactgcgc
     2101 ctgtaccagg ggaggccaga ccagtactgc ccacatacac actcccacca gaatcagttt
     2161 gcttcgcatc gtgtgtcctt tatccctgag accgtcgctc gcccaacaat cctcggttac
     2221 gcaacaacac cagcaagcgc tcccgtagat ccgcattcgt catgagaccg gctccgagcg
     2281 gctttaagaa gttctcctca ggaattgcca aataaatcat gggcaccata tgcacgccca
     2341 cattctccgc catgccattg ttagtggcgg gctgcgggta ctccggcaat cccaccccgt
     2401 ccagcgacac aggtttcacc gtcagtccgt aggtatcggc aaagaccttc aataccttgg
     2461 actgttcttg acaaaacggg caggtcgagg tgaagaagaa gaacagtccg acccggtcgg
     2521 ctgtgcccgc cagaagctgc tcttcggtgt tccgcttgat ctcggcttcg acgctatgcc
     2581 cataggtgga cgtggggtgt tgcgatgcat agtcgagttt ggggtccgtg tacatggcga
     2641 tctgccatgc atcggtgaag cgttgcgagc ggtcatacgc ttccttttgc actttgatgt
     2701 aagtcgtcac attctcgacc gaaggatgat ccaacgcgcg ttccttcttg gccgacacca
     2761 gttcacgcaa taccgtcatc ggaagggcgt tcaacttcac gccctcgacc gaaagcccct
     2821 taaacagagt tcggtacttc gacgggtcca gccaagcctc tggtggtaag ctatccatcg
     2881 taacggggac aggactctct tctgcgtcct cctctgcctc ggctgacggg tcctgataag
     2941 agaaccaccc ctgcctggga tggtcgataa aagtctgaga cccaggaggc tcagcggcca
     3001 gcacagcgct gctcacccct cccaccgagc agaaggtcac gcaataccaa gctagagcat
     3061 gcagcagttt tgtcgtttcc atagcagcca cacaaaatcc tctccaacgg ctggcacgat
     3121 tttcccgagc ccccacatca tgagtgtccg tcctagaggc tgacagcacg ggggagggag
     3181 tcctgtgttt ggaatcggcc agagtaattg aaacttgtac tggcttttca caatgagtgc
     3241 ggtcgggatg tcctcacaca gcagcggacc attagcggag gtccaaaact ctgttcccgc
     3301 gcgggccagt ttcgctaaca atcgcgtcat cgacagcgcg gcaggtttga ggtccccatc
     3361 cgctcctgag acatgcccag tcggcggata catgaatcca aagctcccgg cgcaccagaa
     3421 cagcggatca attgggaaac cgactgctgc agctaccgaa tcggccgcgc aggccgcgag
     3481 tgccaccgga ttggccagga ccaatgcctc cggaaagaga atgagtgaaa tcaggtcgtc
     3541 gtcccacaag ggatcaatct cggaggcata ggccaaatcg atttcgtctg caatcccggt
     3601 aggattcaga cacagaatgt ccattccgat accaacgatg gcccataggg gaaaaacgaa
     3661 ataatgcaca tgaaaaaagg cataatttag ctcggagtcc atctgtgtcg tagccatgcc
     3721 acgcccgatg taactgaacc ccccggccaa agacacaccg agcgtcggaa agcacagtgg
     3781 atcgtggacc gcctcgacaa gattcttcgg ctcccagatg cccagaggta gcccaggaat
     3841 gcagatcgga ccaagacaca cacacccaca caactgcggc ggaaacgggg cgtgtccagg
     3901 accgatggcc ggttcggtaa aatcttctcc caggttaaac accgtgaccc cgctgagaga
     3961 aatgggaaac atgcactccc aacacgtcgt agcgagacta ttcgccaaca cattggtccc
     4021 tgtcgtgcac accgcctctg cagagcccga cggccacaga gtcaccacgc cgatcaggac
     4081 acaactcagg cagaccagca gcagcatatg ctgtatccgt cttttcgaga gcttattcat
     4141 gaatcgccac ctcctccacc cgcagatgcc gacctagctg agagacgata ctgggtaccg
     4201 caccgacccc catgcgactg acaagcagag gattcgccca atagacccgc tgatgaagtt
     4261 gctccatcac tttctgcacg tcgccgtcag agatgatcag cttcacaaac ttcggatcat
     4321 gctctttcaa atactgctgc acccaaccta cctgtgagga actggtgcca tcgaaaaaca
     4381 ccagagttcg aatccaccgt accttgtcga agggattaat tttggtgccg gacttgatta
     4441 acaccgtgtt cgtcgtgggg tccttaatat cctcgggata ctcgaccgtt ggatcaacga
     4501 gcacgaccct cgcttcttcg gcatgcggaa gggccaaccc tgggcccttt gcgaactgac
     4561 gtttgagggc gtcgccagac cgccgttgaa tatccggcca atccgccttc gccacccgct
     4621 ccttcatcac atcgatcatg tcccgctccg cgatgtcggc tccacgtgcg tcgccctgca
     4681 ccttcacact ctgcccaatg gtcggaacct gtggcggagc ttcttccgtc ggccccccct
     4741 gaagaaaccc tcggtgccgg cgctcgaacc attcgatcca tggcatcaca cccgcctgtt
     4801 ccttcgacaa caacgtcagg agatgcgcga ccgaagctcc tccgctcgct actaggaatt
     4861 tctcgtcttt cacaaacacc agggccggaa cttctcccgc accaaccgtc cggtaaatga
     4921 ctggatcaat cccgattcca accagcagtg agtcatctgg atgatccccg gtgaagagca
     4981 gatgcttgat ccgctcctgt gtaaccttga acgaatcctg caccagtcca cgcaagagca
     5041 ccttggcgcc aagtaatttc gcctctcgca ggtagtcttt gagggtgtcg ttcggtaacg
     5101 agaaggagag tagaaggtag acgccgtctc ggcgcacttc ttttggtgac tcctgaggac
     5161 gcccatgccg caacgcttgg cgcgagtacc ttgcgatgtc ctgcgccatc tcctcaggag
     5221 atgggatact tggacgtact gctgattggg agcttcccgc gaaaacagaa gacccgatgc
     5281 tcagaaggga gagccctgcg accgctacca cacagacaat accgctcgat acgttcacgg
     5341 tacctccatt tcagaatgtc tgtatggagt attaccgacc tagctagatg agtggtgtca
     5401 ccgtgccgag aatatccgcc ttccgaatta ggccatagta ccgagagtcg aacgaccgcg
     5461 ggtgtggcag cgccacatag tattcccctt ccggaataac ctccggaagt gacgctagat
     5521 cgatccgttg cccgtaacga tcgatcccaa atccacgccc cacggattgc ccgttgatat
     5581 agacctcgtc ctctttgatc acgatatggt cacccggcac tccaacgatt cgtttcatcc
     5641 accgattccc cacgtccgca tagtcacggt gtaaatggcc tggctgcacg cgttccacgt
     5701 agtcccgccg catgatgaac gccacgagat cccctcgtcc tacgggctgc cctttttgaa
     5761 tgaggaaaaa gttatggtgc ggccaactcc cgctcatgcg agcggcgacc tcataccaag
     5821 gggcgataac gccggcagta ataatcgcac cacagaacaa catcaacccc acatgcgtcc
     5881 agcgatgccg atcaagccag tcgaggattg tcggcgcccg cttgagcacg ttcagcagcg
     5941 ataatgcatt gaatagcttc atcgatggag agctcctttg gtccttcttt tctcacgcga
     6001 tcaatcatcg acagttcatc cggattcgtc gtaaacaaca gctgtgtctc acgcggcacg
     6061 gttagcctgc aaatgcctct cccaaatggg gtgatcataa aaatctcaga gtactccgtg
     6121 gtctttgtga cggatgacag gagtcggtat tccatttccg acaatacaat gcgcccattg
     6181 ttcctaaacg ccgcgatgct ttcggtcttt tgcttgagca gtcccacaaa ttccgcattt
     6241 tcaagcaaat agcgcccaac atcccgcatc ttgtcgtagt agtcgttgat gccctgcgtg
     6301 atggtgatca ttgagccacc ggacttccgg acccggcgcg cgccggtttc aaaaaacgca
     6361 gcggtattgc ctccctgaga caacaaatcc cacgcctcat ctagaatgac gaatttccgc
     6421 cggccacggt tctccttttt gtacatcact gcctggatat tcatctgcat ctgcaggaga
     6481 atgactgacc gtaactgctt ctgttcattc aatccgtcga gttcaagcac cacaaagtca
     6541 ttttcaaaat tgacgttgtt cgccccgttg aagagatggg aatacatacc ccccttcgca
     6601 taggaagcca gcacacgcgc gagatctctg gctcgaggat cagtcatgct cttcaacacc
     6661 ttgtgtaccg aatccggaca tccctcacat ccctctcctt cgagtacgcg catgatcgcc
     6721 tcttcgatga acgagagctc gacatcggag agcgggcgcg aaggtgacgc catttgcgcg
     6781 tgcaacgctt tgagggtcgc cagttcatcg gctcggtcac ttggatcgtc aaccccgccg
     6841 gcattactcc cccaatgcac aagtttgctg aacggattaa aacaaaggcg ttgagcgttt
     6901 gcgccgtact ggatgtattg ccccttgagc aactccacaa gtttgacgta gctgaagcca
     6961 gcatcgatga cccacacctg gccaccaata cccaagtagc tcttgatcca attgttcata
     7021 aagaacgatt tacccgcccc cgatgtcgct gcgatcgcca tgttgtaatt cgtctgttga
     7081 ttggcgaaca catccatggt gatcaattga cctgaacgag acgtcagcag caccactgga
     7141 gctccgcccc ccttccagtc agccacaatg ggacaaatat gcgccgggac ctcggtatgg
     7201 taagtcttca ttcgtcgcag accatcaatg agcgctttgt cgtccgacgg tagtccgagg
     7261 ggtagacccg tcataaggat tttccatcca atgaagtgat cttcctgcaa gttgatatcc
     7321 ttcgcccgat agagagcccg aagggcgcct gtctgctcct ccacatgtcg cggtgtatcc
     7381 ccatacagaa cgacctggaa ataggaccct atgagctgtc tgccattttc aagttgcgct
     7441 tggacgccat tgaaatgatc caatttgaac ttgagggagg gaataagccc cagaagaaac
     7501 ccactggctt gctgattaat aatgacgtgc ttctttcgaa gcttgccttt cgctttgacc
     7561 tggtcaaatt tcaacacatt cagcgtcaga aaaaatggac aggtaatttg atcggtgaac
     7621 cggatcaagc tcccaatcaa ctcgcgattg ttcccgccat gccactgcac aggccatgac
     7681 tgaacagtca gcgtcttgag aaactttccg tccagttcaa tcatcttggt gcgaagcgtc
     7741 gccttcgtat cgagacggac cgcctgatct cgtatcggca gttggtcgct gtacgccggc
     7801 ggccgactct cccagctgtg gcccggattg agcaacacat gcaagagact caataattgc
     7861 agcggcccta cgcgctcggg caataatccc aacgtgttca attgcccctc aatgcccgac
     7921 accgcttgat gaatccgctc gtcttcccat ccttgcgcgg tcgtttcctg cgttgggaac
     7981 gccacggata catacaccgt gaaatctcgt gggcgcagag gtgggttaga cgtcagttgt
     8041 gtatctctgg catgcagata gaactctgcg gtctttctcg catcagctac ataacgttcc
     8101 cctgcctgac ctcgttgcgc cagaatcacg tgattgtcca gatatggctc gataatgggg
     8161 gacgcatgaa gcatgaattg aaacgtggtt ccaattggca ggtctgactc gaagagattc
     8221 gtcagcttct gaatagactc ttccgacaac cccagtaggg gcttgctaga aaacaccaca
     8281 ccgatacgcc catcatccaa tcgatagacc tgattggtgt catcccaagc ctcatagggc
     8341 agccagtcac tgatggctgt ccgatcgacc agctgcttta ccttccactc aaggatcgtt
     8401 gacatattcg ctcctctggg ttccttccac tactggggtg gcagcggccc atcatcggtc
     8461 agataattgg acgccccggt ctgagggagc tgaggaaatc cctgcggcat gatgccaccc
     8521 gagccaagag ggttcacgga catcggcgcc gaacgttgtc caacttcagg aacattctcc
     8581 gtcatggcgt tcgccgccgc attcccactg ggtgttctct ttccgtctcg tttctcgacc
     8641 atccgcccca ttctcggata cagatccttt ccatgccccg aactcgaccc agcactcacc
     8701 ccctgcgcca tgtgtccgaa aataaaatct ggttcgtcga caatgagata gtgccgcgac
     8761 tgatcatgga ggcgcttttt cgtatccttc catggaaata ccgtcacacg aagagccgac
     8821 accggcgtaa tcaccggctt gcctatggcg ctgtccggct tgccgctgaa gatcatcgga
     8881 ggagtgacct gaccagggcc agagcttgag ctggtgtctt gtccaacgcc cttttggtct
     8941 ttcgtgtact gcgtcacctt ctgcccagca gagaaccgct tctcgtaggc ttccgagacg
     9001 gactcacacg tcgcttgatc cggatacccc ttacaactga aattagactc atagccccca
     9061 cagcccgcca gaaggacaga caggcccata gctaccccag atcccaagcc gtaccatgat
     9121 ccgcctcgtg tgatgtagcg cctgatatac ccagacatca tgtcgcatgc ctcctccaga
     9181 atccgcccac tcgacttctc tacttctgct gggcctctat ctgcagtaaa gccaatactt
     9241 cactggcagg acgatagccg gcaaacgatt gtccatttgg caaaaacacc attggggtgg
     9301 agttcactcc caaacgcttc cccaatttga tgttctcgtc gatcggatga ctgcaagccc
     9361 ctacctcacc cattactggt tttgacatca gcgcgcgccc cagcgcctcg gcttgatcgg
     9421 gagcacacca aatggcgaca gacttgcgat aggcatccgg atgcgtccgt accagtggat
     9481 acagaaccac ggccaccgga acacctgcct caacaagctt ctgcacctcc ggatgaaact
     9541 gctgacagaa ccgacagtct ggatcgtcaa agaccagcac cggacgctcc aacttcgatt
     9601 gcatgggaga caacagaatg gttttcgagg tatccattcc ggccaagagc gcctgctgac
     9661 ggtctctcac atactcttgc gtaacatttc ggcccatttg aatatcgaag agtgccccgg
     9721 agagcacgta ccgcccagac tcatgcacgt acatatagtt ttccacccgg tcactgtcgc
     9781 tctccaccaa gagccatcca ggaatttccg tcttggacac tcgcaacact ttcatgccag
     9841 gaaacttttg ctcgatcacc gttttgatag gcctcacggc atcatccgtt tcggctctca
     9901 ggatcgactc tcccgcaacc gacacacaca cggcacacac cagccccgcg attatctttt
     9961 cataggatcg tctcatcgcc atcatgcccc ctttcacact acgaattact ggaagaaccc
    10021 ctctaactca cgtcctgtcc caacgatgaa atccacttcc cgttgcgcgt cgatttcaat
    10081 caccgggaaa atggaggcag ccatcatgct gtagtggcga gccaacaatt cagccgcccg
    10141 accggcacca ccggccattc ccgacatcgc cacaggcccg gccggcggta agttgaaggc
    10201 ttggctcggg ctttgtgcga cgaaaaatcc ggactggtag ggcataaagg ctcgggagat
    10261 gcctgacaca aaaccagcga gcagcgtgcg acccaacaat gccccctctt tcaagacaac
    10321 ccgcccacgc attccctgtt tgccatcttc cccactcaca aaccctttca attcgatatc
    10381 taccgcttcc ccattcttct tcacgcacga caaggcattg ccacgaatca tcacgcgttc
    10441 cgaggacaaa tctcccaagc cttctcccac taggaaacag tccttcgcat caatcctcgc
    10501 ctcattcggg agcttcatga tgtcacgcac catcatcagc accgggtagg gactgtttgc
    10561 ggaggcgccc ccaccctgcg cccccgtcga acgggccggt gcatccatgc cagaaagcaa
    10621 tttgacggga ataatcgtcc ccgtattcag ccacaatttc ttctcgttct ttttggcgcc
    10681 aggcactatc tctggccgaa atacctgaaa cccctcggtc aacccgcccc cggccccagg
    10741 ggccggtagc gtcccgcctg ccggtttcgg ggtgctttgc accggaatgg ggcctttcgg
    10801 aaccggcatg gtcgagacag gcgtcgcact tcctccaccc acgggattgg cactgagcgg
    10861 aggcggcagc ggcggcaacg cgccactctt cgtcccggct gagaccacgc caccagaccg
    10921 cgccactgac tcaatccgct tctgcaggtc actcaactga gtcttaatct cggtcttgtc
    10981 tcgtccgtcc tgctccaaca atctccgcat ttgatcccgc tgctgctcca acgcttcgat
    11041 cctggccccg gcgtctttca tataaatttc tttgtcggtt tcctcgcgat tgatcgacac
    11101 ggtcttggct ggagacttcc cacggacaat ccccggttga ttccctcgga attgctgaag
    11161 caccatgctc agcacgatga acccacccac cagaaccact cccgcgagca gtttggatgg
    11221 agcgggtttc tctgggcgaa tcgggtcgcc agggttgaga atcgcgctct ccgtcggttt
    11281 aatcgatgcc atcctaggtc tccggtctga ggttagcttt ttgcgtctgg atccactttc
    11341 ggctcgggct tgggtttggg cggttcaggc ggtgcgtcat ccagcaggta caccaccact
    11401 tcttcccctg actcgaccac ctcgcgattt aaggcgattg ctttttgaac cccggtcagg
    11461 aattcttgtt cccgcagtgt gtatttgtgt cccgcggtat tcaccaatcg atacacaatc
    11521 acccggtact tcggccctcg atactcgatt ccctgcacca ccttcagctc aagccacttc
    11581 ggataccgtt cttcggcaat cgacgtctgc cgataccctt tcggtaacgc tccccgcgca
    11641 gccatctgca atgtctcgag tagcccatcc acatagtcag cggcttggcg agcaggatcc
    11701 gtgtcataga ccacagtccc cacgcgccta tcttcaatac taatggtctg cgcgcctaac
    11761 gacacgctca ccccgacctc aaagacgtag gtttgctcgc cggccatcac gaccagatca
    11821 gcggggccag tcttcacctg gacaatcaag ttgcgccctt ccggcttcgc tttgagatcc
    11881 gccctagagc tcgtcgccat ggtaatcggg gcaggaaagg tcaggacgtt caaatctctt
    11941 ccagacaatg tgagggacgt cgcaccctca tcaccaacca ccaccgcagc tcctaccgac
    12001 ctggcccaag acagaaacaa cagcaggcca aggacgcaca tcgccatcgc ccggtgcttc
    12061 gagtctcgat acacgctgga tgtcatacgt ctccccctac ccctttgccg gatctgattg
    12121 actatcctgc cgtgaacgat ctaaatgagc cgcagagagc ccaaccaccc acggcctgcc
    12181 ctgatcccac cgcatcgaga tacggtactc ccgctcctct tcccgtatct cgctctttcc
    12241 cacaaatcgg cgctcaatgc cctcgaacac ggccacgtcc ccgtccacac gactagccgt
    12301 cacaaaaaac acacgactga gattgttggt cttcacgtac acggcctccg ccccgagaga
    12361 ctctgacata agcccatagt ggcttgacgg tacccactgc agaagctgcc gatggtgaaa
    12421 ctcaacagag gccggcgtga cattggcaat ccagggcaac atggccatgg caatggactt
    12481 tttgtaatac tcgtcgccgc ccattgcgtt cgcccaatat tcctgcgtcg gattgatcgg
    12541 caccacatga accgcgacgt tctgccgaaa aaatccgttc gccaccaacg ccaccgctaa
    12601 tactgttgcc agggcggcga acaccagatt caagacctgg gcgttatgca attttgattt
    12661 ccacagctcg attgtcatcg tcgttactcc atcatctctc gggttgttcc gtgaggtgat
    12721 cccgtcagct gaaacgtggg cacaccagac caataggccc aatggaagag gaatccctcg
    12781 gatttcccgt tcttcatttt cgacaaaatc aacgtgctca cgatccccac cactatcagg
    12841 taggtcagga acttcgtgac aatgccgaga aagatgcaca caaagagcac ggccaactca
    12901 tcaatctccc accaaaagat ctggggcagg ctatcgagat atcgtggaat aaatgtgccg
    12961 ttcatctgtc cctcttctgc ttcattgtga cggcggggcc atgatctgtc ccgccgtcac
    13021 gacaccatgc ctgtaccgcc cgcttacatc agtcccgtgg taatggtcgg aatgatgttg
    13081 gggatataga aggctgctgc cgccacaccg aatccggtga acatgccggc ccaccggccc
    13141 gccatcgccg atcccaaccc gatcgccccc gccaccaggg ctaacaacgt ccccagcgac
    13201 ccctgcatat agttggtcaa caacgtgacc agcggaccaa acgtcgcatc cgcacctgcg
    13261 aacgcgggga cggccagcac cacaaacgag gcaagcacca tgagccccaa caagagactc
    13321 attcgccaca tttctccggt cactctcttc aagacgttgc ccatactcca gcccctcctc
    13381 tggctcgtcg ctcactgttt acaagacgtg tggttgccaa accgaatgag cgcccttagt
    13441 tcattccagc atagccatgc tcctcctcag cctctcctta tggttttact gagtcgcctg
    13501 tgacaccagt ggacacaaca gatgttactg gaggtatttg ggatcgctcc tcaaccgatg
    13561 agggatctcc acacctacct cgcagcagca tcgtgatctc cacgcgtcga ctgtccgcat
    13621 ggttcggcat aaagcagcag cctccgcggc cgaccacttc cacctgagtc gagaccttca
    13681 agccagcctg caatgctttc gccaccgcgt gtgcccgagc cgtcccaagt tcttcgtttg
    13741 tctcccgaga ccccgtcgga tcggtgtatc cctccacccg tagatagaag acctcctctg
    13801 tggacagttc cgttaagtct cgttgcgcac gctccggtac agcagccgaa cccatggcaa
    13861 acaaaacggt tcgatgccgc acctcaggat cgcgacgaca ggcggacggg gacgtccttc
    13921 ctgtgaaacc aggaggtgct ggtttgtcca cgctgctcac cgcagcgcga gacatgtcac
    13981 ctggacggcc tgccagcgca cccgcagaaa acgtcggcaa tgtctggagc cgatgcatca
    14041 ccgccttaat cggtttcggt gtgagatccg ccaccaacgg tttgtttggg acctgcgtca
    14101 ggggtgttgg ctctgggcat ccagcgggac gagacagaag ccattgcgga ccagattgga
    14161 cggaaaccac cgtagtcggg aaggtgtagc cttgcccgca gagtcgcgtt gcctcggaca
    14221 ttgttggcga cgcagcaggt cgcgtcgtac agcccccgac ggtcagcagt cccatacaaa
    14281 cgagaccggc ccatggcatg taagtcgtcc gtccccctgt catactcccc cctttcacca
    14341 cggcttccga gtcgccaggt tcatctttgg tattaccgac tgccacggtg tatcgaacag
    14401 aaacaggggt tgccggatgt cggaagggac gtcgtcgacg cgacgacgga accaagaaaa
    14461 gacgccagcg ggttaagaag cgatcagatt aacagtagcc acccccccac cccaggccag
    14521 gaaggacccg tcgggacatt gctggaataa acgcgcgcac tgaagacact gatgaaggta
    14581 cctatccatg aattcgtcac catcgtgtga acgataccca aacaactctc cgttacaacg
    14641 aggacacggt ttcaacaaat ttgcatacag tcccattgtt tgctctcctc gcttcactac
    14701 aagacactcg tattattatc tgggataact gcatgcatca ccggtgcatg gatcagcgtg
    14761 ccgagggtcg ccattctgga ggcaatcctc gcgattgcct cctgcgactc acgcagcgcc
    14821 tccaattcga cgcctcgctg ctgagctttt ccttccagtg cctcgcacaa cacatcaagc
    14881 cgccgcacaa tggttctgac ggccatctct tgaaattctg cggattgcgt acaggccccc
    14941 acgaaccctt cggtttcgag atccgtcgat ctttccttgc caccttcctg ctgccgcgta
    15001 cgatgagcct gcacacgcgc ctcgatacgc aagaccgcac tctcgaagcc ccgtaattca
    15061 gagtcgttgg aatacgtcac ctgttcggca ttccaggcac tatccatagt caaggccggc
    15121 agacagaatc ggacgagata actataggaa aggggaaagc tcaattgggc gcgcagggct
    15181 tcaatccgct cccactgccc tccgaaggcg ttgtagatcc tcgcggactc gtacagcatg
    15241 tgtggacgaa tacacttccc gaccgctgcg gacatacgtt ctgccatctt cacgacgaca
    15301 gcatccccat gctggctccg ttccagggct tcaaccacta taccgccaag ccgaaagcgt
    15361 tcgcggatca actctcccgc cacatacgtg atggacctcg cacactgttc agcccgttgc
    15421 accaacgatt cctgccaatc agccgcgtac tccagcatca gccctcctac tgcgctagaa
    15481 ggcatagatc actcccactg acccacgaaa cgccgcttgc ccaacagatc cgaggaaatc
    15541 acgggaggca ctcaacgaga acaaccagtg tttgtccaac gccaggacat accccagctc
    15601 cggactagcg acttgcttct tggaattgag cgggtcttct tggaatcgca agccacccac
    15661 aatcgcagaa gattcatcca gggcttttac aaaccccaag ttcacaaaga tgatgctcga
    15721 acgatgcggg acccaatggc ctggctgaaa tgacggcacg acctcatatc ccagattgcc
    15781 atggagccac caccgattcc caagattcca ggacgtgacc aacgccccgc gcaagccagg
    15841 attcgttcgg tctcccgcat agggcacctc acccaatacg cgcacgctaa tcgatggcag
    15901 cagctctcgt tcttcggcct gtttccggaa ccgcgctaaa attcccaact ggatcgacct
    15961 aggatcgtcc atcgtcccag gattgagcgg acctcggagc gacgtcccac tgaccgtcaa
    16021 ttccatattt tctgtggcgc catagcgaat atcgtgagtc gcccggaagc gcccactctc
    16081 agagcccgaa tcattccgcg tgatgtcggg ccggatcgcc gactggatca ccacttgatc
    16141 tgtgggcacc gggtaggcgt catcgagaga cgtagggtag cccggactga tatttaccgg
    16201 ggagagtgcc atcaccacgt tgccccccag gcatacgagc cccagggccc ccgcaaccgc
    16261 cagtaaccac ttcctgcctc cacgcattag tcccaagctc cttataggaa ttgcacaaca
    16321 tagaaggttg ttaccctcgt attaccgaag gaccaaggac aggaaaggca ggagattttg
    16381 gatcgagtag acgtcagggg cagaggagag aagatgtcag tgtcacgccc cctgacaggt
    16441 ccctaatggc ccattccagg gaccatgagc caggcacaat tcgcaaggag agccgtggat
    16501 cagcgcgatc cattggccgt gtgatcc
//
LOCUS       DAOQPD010000089        16342 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1785_length_16342_cov_23.368392, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000089 DAOQPD010000000
VERSION     DAOQPD010000089.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 16342)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 16342)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16342
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1785_length_16342_cov_23.368392"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            290..2809
                     /locus_tag="PK063_15995"
     CDS             290..2809
                     /locus_tag="PK063_15995"
                     /inference="COORDINATES: protein motif:HMM:NF018010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLBB domain-containing protein"
                     /protein_id="HMZ98603.1"
                     /translation="MVLPPSLLAQTLTNPAIPSSPSGASASPSIGSQISPFLPFGTYG
                     LPTAPGQAIVTNPTATQPIVPQHAPCPIPTAPDLSPENTVPNLNDYWPMTANSLLPTS
                     VEQRMRQEEEERDRQLERVQAEKEKRGLELQSQVEREKKGVSQLQGLQSAMQGAVGGM
                     QGQVQNQLNQPKQPLEQKQFTAELLRHQDFSVEEAFAQFSVLQGVKSRLKQFGYDFFD
                     AHAGGFAALQDVPVGPDYVIGPQDSLAVHIWNVPDQSFNRSYIAPVERDGMVIIPQVG
                     AIPVGGQTFSQAERTIHARLSMLLKRFELHVSMARIRTMKVYVVGEVARPGAYELSAL
                     ATASNAIYAACGPSRSGSLRQVRIMRDGKTIGQLDLYEFLLQGDRRQDHRLQAGDVVL
                     VPPLGSVVAISGSVKRPAIYELKPGTRLTELLTLAGGLTPLSDRQRCHLFRQDPALQE
                     RNMIDVDLVRAFASQGAEKSRPGVEGGDPLLMDGDYIRIATLPTQVVNVVSLVGAVKS
                     PGPYEFRAGMRVKDILTPEQLTVDAYADRAEIVRTDPATYLTKVIPFSPKAVFEGRES
                     DNVALSRLDQVVISSQMRAPALVLVEGEVRRAGYFTIEIGERLSSVLKRSGGFTPNAF
                     PNGIVLVRESVKVKQQAELDRFIAAERQRLTAQSAGIAAGTAGLNVMAGASGAMAEQQ
                     VLALRLQQLEATASRIELGRVIVSLDSIERLEGTEDDIILESRDRITIPTPPQTVGII
                     GSVKSPTSVVYRPGLDLNDYLRQAGGVTEDANKREMYVMRANGTTDSSYLSAKEMRPG
                     DTIVVPQKIEARPPQLALWQTVASIIGSLALTAAGIAVVGR"
     gene            2826..4052
                     /locus_tag="PK063_16000"
     CDS             2826..4052
                     /locus_tag="PK063_16000"
                     /inference="COORDINATES: protein motif:HMM:NF014732.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNVR domain-containing protein"
                     /protein_id="HMZ98604.1"
                     /translation="MDWPSDSPHALLDPPRSTVETLPADQPVTLFDYWDVLVARRKMI
                     AAFFLFGTCLTLAISLLLPKIYESTSSVLPQLESKEGGALAALLTAPGAAGMAQNLGI
                     GLPGLPTTPTDVFVSILKSRLMADEVIKKFDLMNRYHESTMVDTRKELEDHLRITVTK
                     EKVIKVSVEDEDPQVAADIANFYVANLDRLNRTVTVSKAGQNRAFLERRLAETMESMA
                     KAEEALRDFQAKNKTVAVEAQAKVMIEAAAMIQGQITAQEVQLQVMGGYLSPDNPDLA
                     RIRSNVEELKKQLAIMGSGKDARGLLSSDRLHPAMVAVPDLALQFGRLFRQVKVQETL
                     FTLLTSQHEQAKIAEARDTPTVQVLDPAVPADKRSRPRVLLNIAVAGVLALIMGTFTA
                     YFLDYRARVRRISTPA"
     gene            4162..5178
                     /gene="hpnH"
                     /locus_tag="PK063_16005"
     CDS             4162..5178
                     /gene="hpnH"
                     /locus_tag="PK063_16005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="HMZ98605.1"
                     /translation="MAVPVSQMYTVTKYVLTQKLRGVKRYPLVLMLEPLFRCNLACAG
                     CGKIQYPDHVLDKRLTPAQCWAAADECEAPIISIPGGEPLIHPEMPEIVRGLVERKKY
                     VYLCTNAILMERKLDEYPASKFLTFSVHMDGLRDEHDLAVCRDGVYDVAVKAIKAALK
                     RGHRVTTNTTLFDDANPERVRKFFDEMMGLGVEGMMISPGYSYQKAPDQQHFLKRSRT
                     TELFSKILSNRKRGWQFNQSPLFLEFLMGKRQYQCTPWGNPTYNVFGWQRPCYLLQEG
                     YASSFRELMEKTDWDSYGTGRNEKCADCMVHCGYEASAVEDTFGSLSGFTKTVKITLM
                     PNAR"
     gene            5273..5662
                     /locus_tag="PK063_16010"
     CDS             5273..5662
                     /locus_tag="PK063_16010"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98606.1"
                     /translation="MTDAKYHAPEPGSLEGRVFRPTSLTDLSEAIELAFDYRGDITVD
                     LKSGGQVTGYLFNRTATGDQPTIEVFPSTSSGTMTIPYSEVMAIAFTGEDTATGKSWE
                     AWIAKKESERQKDIDRAAAEAKSRGHL"
     gene            5830..6486
                     /locus_tag="PK063_16015"
     CDS             5830..6486
                     /locus_tag="PK063_16015"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase-like regulatory
                     domain-containing protein"
                     /protein_id="HMZ98607.1"
                     /translation="MLEESASNLGRVRVEEASRKQALGEMFVRPKTSPARIERMRGRR
                     EISKNTARHVVLVWGLIATLCVPSVLFASHAADHRFTVEGFVCGKDGRPAVNVEVLVK
                     DTRITVGQTVTTDGDGYYKVTLHLHNDNVGDPLLVEAAGEQKNSKIQFDPNDLETERK
                     LRIDFGSGCERDLGPPQWLLYGLGIAAVAIVGWIGLKISRKRMREEQRRKKGQGKRQK
                     "
     gene            6698..7204
                     /locus_tag="PK063_16020"
     CDS             6698..7204
                     /locus_tag="PK063_16020"
                     /inference="COORDINATES: protein motif:HMM:NF012264.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="c-type cytochrome"
                     /protein_id="HMZ98608.1"
                     /translation="MKHAGMTRLALMVGILGFGFGVVGCGGGGEGGGEGPVVPPPPAP
                     AEYADKHMPAGWWTDPKILEEGKELYIGGKNPDVNCASCHGKDGKPVKAGARDFRNGD
                     RMKMYSDSVWFWRISEGVPNTKMKPWKSKLSEEDRWKILAFERSFGLSGKGWDANKKD
                     WVPADQVK"
     gene            7270..8973
                     /locus_tag="PK063_16025"
     CDS             7270..8973
                     /locus_tag="PK063_16025"
                     /EC_number="1.10.3.-"
                     /inference="COORDINATES: protein motif:HMM:NF013791.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0070069 - cytochrome complex [Evidence
                     IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_process: GO:0019646 - aerobic electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="HMZ98609.1"
                     /translation="MKIWQRCLLVMFALVAVLGGVAYAQAPSAPPVEFPYTGNRTAVW
                     IVAQLHILFAGFILGAPIFVVISEWLGYRKQDPRYDRLAKEVTKVTVILYSMTALTGG
                     LFIFVLLATYPQFTTWLINHFFLIFAVVYPLLFIGETIVLYMYFYTWDAWKGEKKGRH
                     IALGVLLNLIGSITLFVIDAPTSFMNTPVRAEGISPAEFLATASLWDKVFNYSWMPLN
                     LHRLVGNVTFGGFVAGLIAAYMFMGSKKEEDRAYYDWMGFVGNMIGVGALLFLPFMGY
                     LLAYELCDYDASICPYMMADQLSMFFEMQGAMIGLIFLASNYYIWLSMKRIEGVERVR
                     MTVVAPIVMVLLPIVMTKVLTDYPVPDATSLAFLLPLLLAPVVLGRFIPLTVSSSTVI
                     KIGFLMVVVGNAIWMTPHGFVPTGAKLVAELELPSDWNFLALMPAKNSAAFTLVFVTV
                     VNYVIYNRAVSQGTIVWGKIDFASQFVLVFLAFSAIWTMGLMGAVRSLLRKYFHTYNL
                     LPDFTAESFTPTLSYSAWWITGITIVFYAVVSFAIIVTLRPSDSKGHAHEGSPVPAGA
                     K"
     gene            9015..9821
                     /locus_tag="PK063_16030"
     CDS             9015..9821
                     /locus_tag="PK063_16030"
                     /inference="COORDINATES: protein motif:HMM:NF012264.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HMZ98610.1"
                     /translation="MGNIIKKLVVGVVVGGILFGATNALGFPFVFQALFFGYAMLGAI
                     VFMILDFPTLKPFGGVKAVGALLVFYAILSVVYIAGASMWPQYDPEDEKGKIEKILKP
                     KREHYEAGKVEVLMQRAKALDEKAKELTARLQALGAAQAPADQKAGGESAPTATTAAA
                     SGDIAKLGEEQWQLQECYNCHKLNGEGGKKRGPELDNIGNLLPAAEIARKILDPKSYK
                     AEGFEQEYEKGKMPDKYKDLMEPKDVDALATWLAGYKNASVNTPKPIKMK"
     gene            9827..10765
                     /locus_tag="PK063_16035"
     CDS             9827..10765
                     /locus_tag="PK063_16035"
                     /inference="COORDINATES: protein motif:HMM:NF012575.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinol-cytochrome c reductase iron-sulfur
                     subunit"
                     /protein_id="HMZ98611.1"
                     /translation="MQPKLKSKVRCTDGEVGEVRRVIMDPLSHEISHIVVGGGTAGVI
                     ERQVPMGQVLAVSDEAVTLRGSSAEFAALPAFKRDEYVTTHEVEIAHLEDRIHVTPGE
                     VLVPFPELERSVKRRTFFANFTHAIGFLIGFPLAFPVLRYLMKPMYSPFDNEWLKIGN
                     SGKIKQDDVGVQFKYKRKIKEAYMPEQEIDKNVWVLKATPKVLETIYQGKDMEFRDSA
                     GKHIWTNKKDVPFVAYSGKCPHLGCGFKWRTHKTLGQVFLCPCHLSIYDAAGKVLDGP
                     APRPLDPLPIKVTATGEITIIDMEFKAGTKAQVRIV"
     gene            10765..11880
                     /locus_tag="PK063_16040"
     CDS             10765..11880
                     /locus_tag="PK063_16040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bc complex cytochrome b subunit"
                     /protein_id="HMZ98612.1"
                     /translation="MDTTTQPTTTQPSAIEKVFAFVDERVGLKTLQAKMLNEPVPGGS
                     RWAYVFGSVLLFIFIMQAVTGILLMFYYVPTADHAYASTQYIIHTVDYGWFLLSYHFW
                     GSTAMVVCVFAHMSQVFLWGAYKKPRELIWLVGLALFGIVMGFGFTGYLLPWDQRAYW
                     ATTVGVEIMDKTPLLGDFMARFLKGGATPGQMTLSRFFVIHVMVLPAALMGLAGLHLF
                     LFRKAGPAGPFRGSVEEIKAKTDYFFPRQIWKDIVGMVAVFLCICSLAFWEPIVLLEE
                     ATPDPGDYHPEPEWYFLFLFQLLRLKVFAGEFGQFLGAIALPGVFMALLAALPFIDRD
                     PERNIFKRPIALISWIVVMASILIFTVAAIINREFLE"
     gene            11917..12918
                     /locus_tag="PK063_16045"
     CDS             11917..12918
                     /locus_tag="PK063_16045"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98613.1"
                     /translation="MSSFKLGLSILWPACWTALPLKMAFAMLFMAMGTIHLETKLGIT
                     FLMLLMSPVSVFAFFVISLGVGFHFGEGTGLPLLFLVSIPIDIWALGLVARTVFLERL
                     RLEPPDSLGLGLWVRFAIAGAVYLPLLWVVEGGATDLARSIVKAILDMDMLKGLPVAE
                     RIGLEFTAWGSASLVVLIALTFIGLTILGKLVEGKTAGAQPSGDSYQGLISRWDMIRV
                     PADQSLMLTAFTAAGAVLSVLFWMVLPVSTPHPHECCKPASVAPVAPFDPQKSLSKGE
                     KVLKDAEVKIAALEQKTAEDEKDKQKGGKEKAGVKDSSAKSDGKASQVTAGKPAGSK"
     gene            12968..14827
                     /locus_tag="PK063_16050"
     CDS             12968..14827
                     /locus_tag="PK063_16050"
                     /EC_number="1.10.3.-"
                     /inference="COORDINATES: protein motif:HMM:NF013791.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0070069 - cytochrome complex [Evidence
                     IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_process: GO:0019646 - aerobic electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="HMZ98614.1"
                     /translation="MDNQVRHMAGRIALLAGCAAMLGWIGLPDTAMAQDAAAQAPTAY
                     RDIPYVGSRNLVWIIAQLHLLLAGFVLGVPIFAWLCEVVGWKSGDKRYDKLAKEFTKL
                     LTSSYATTALFGGILLFLLIGFYPKLMAYLTDIFFPSFLVYCGLFLVETATLYLYWYG
                     WDAMSEGNGKKFHIFLGFLLNVFAFFIMIVPNSWATFQASPVVIAEGTDFERAWAATW
                     NPTWWPVNIHRIIANVVLGGYICGAYAGIRYLSAKSTEERYHYDWMGYVGNFIGVFGL
                     LPLPFAGYWLMREIYQYNQQMGITLMGGFLSWLFILQAMLIGVLFLGSNYYFWMGITH
                     RIPGSEGQYRKPIMAMLIILLMCLAVWMTPHSLVASLEEAQKMGGTHHPLLGVFGVMS
                     AKMTVSNLMVLVTFMSFIMYWRAGKEDTAGWAKVAKSVMGAVLVLAGLAVIVLGVWGY
                     FVPAIIRINYFSTSQVAIVIFVMLTITPLTALLLKSAKTTTEMVWGRMPPRAGYSLVL
                     NAVMVILLMTLMGYARSSSRVHWHVYGVMRDSSQYAFSPALGYAAALMALCTFLFCML
                     VAFIFWVATMGDKAKAAASAKGAPEPGHIPAMAGGSPALDGPASDASEGNRPV"
     gene            14894..15514
                     /locus_tag="PK063_16055"
     CDS             14894..15514
                     /locus_tag="PK063_16055"
                     /inference="COORDINATES: protein motif:HMM:NF012264.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HMZ98615.1"
                     /translation="MSEVVKLQLIGLCVVGLGTVILLFIKGQFLRVIGFVAIVLGLFA
                     LVALAVPQMASLPPAEESINIADIKTATDMATIGQKIFFSKGQCALCHSIGPSESARC
                     PDLKGIGAKLSREFIFESLTEPQAYLYLDYRHEGVPKEYPARMPYINRNPIGLSKNEI
                     LSVIAFLQQMSGEPISVSPSELDIPRATPAPVKAADAGTVAVAQAR"
     gene            15545..16270
                     /locus_tag="PK063_16060"
     CDS             15545..16270
                     /locus_tag="PK063_16060"
                     /inference="COORDINATES: protein motif:HMM:NF024834.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HMZ98616.1"
                     /translation="MGGVLIRPIILTVCIYLFLKFIVPVLPHSAPLPSSLIFLYLMLV
                     MSGSVLFATLSGESKDAFFQPILRFLTGESGGALSSARYLVLALFPLLVGWQAYGSTA
                     SSDAPPGENRTIHPAPPGEYTGLSNPVPKTPENIMYGKGLYASRCAPCHGNFDGKGFA
                     AAGFTPPPANFKDPTTIAMLQESYLFWRIKKGGVGLPVEGMPWKTAMPRWELEMSDED
                     IWKVIMGEYDGAGQKPRTWDESE"
BASE COUNT         3365 a         4295 c         4901 g         3781 t
ORIGIN      
        1 atccgggaca ggtgtcggcc attacgccgt ttgctgaaac cttcgccgcc ggcgtcacag
       61 cgaaaaatca tctcctatgg accgctgtgg ccgtgcaatt ctagctgcgc tggttccggc
      121 ctcgattgac tgagccggtg actttggatt agaacctaca gtcgttatcc acaggcgaga
      181 tcgttaggac agtatgccta ttgtaatgcc atggcgtgtg ccccttgttc gtagtgggca
      241 aatcacaggc cggtggatga gggcggtgat ctggttcttg gtaggaggta tggtcctgcc
      301 accgtccttg ctcgcgcaga cgctcacgaa tccggcgatt ccctcttccc cctccggtgc
      361 atccgccagt ccttcaatcg gcagccaaat ctcccccttc cttccatttg gaacttacgg
      421 gttgccgacc gcaccggggc aagccattgt cacgaatccg acggcgaccc agcccattgt
      481 tcctcaacat gccccatgcc cgattccgac ggctcccgat ttgtcgcccg aaaacacggt
      541 gccaaacctg aacgattact ggcccatgac ggcgaatagt ttgcttccta cttctgttga
      601 acagcgcatg cgccaagaag aggaagagcg cgatcggcaa ttagagcgtg tgcaggccga
      661 aaaagaaaaa cgtggtttgg agttacagag ccaggtagag cgggaaaaaa aaggcgtctc
      721 tcaacttcag ggactgcaat cggccatgca gggagcggtg gggggcatgc aggggcaggt
      781 ccaaaatcag ctcaatcaac cgaaacaacc gctggagcaa aaacagttta ctgctgagtt
      841 gctacggcat caggactttt ccgtggaaga ggcctttgcg caattttcag tcctgcaggg
      901 agtcaagagc cgtctaaagc agtttggtta tgattttttt gacgcgcatg ccggcggttt
      961 tgccgcgttg caagatgtcc ccgttgggcc ggattatgtg attggcccgc aggattcgct
     1021 ggccgtgcac atttggaatg tgccggatca aagtttcaat cgcagctaca tcgcccctgt
     1081 ggagcgagac gggatggtga tcatccctca agttggggct attccggtcg gcggccaaac
     1141 attttcacag gccgagcgta cgattcatgc tcggctgagc atgctgctga agcgttttga
     1201 attacacgtg tcgatggccc gcatccggac catgaaggtg tatgtagttg gagaggtggc
     1261 gcggccggga gcctatgagc tcagtgcatt agccacggca tcgaatgcca tttatgcagc
     1321 ctgcggaccg tcccgatctg gttctctgcg acaggtccga attatgcggg acgggaaaac
     1381 catcgggcag ttggacttgt atgaattttt gctccaagga gaccggcgac aagaccatcg
     1441 acttcaggcc ggcgacgtcg tgctcgttcc gccactcgga tcggtagtcg ccatcagcgg
     1501 atcagttaaa cgaccggcga tttatgaact caagccgggt acgcgtctga ccgaattgct
     1561 gacactagcg ggcgggctga cccctttgtc tgaccgccag cgctgccatc ttttccggca
     1621 agatccggct ttgcaggaac gaaatatgat cgatgtggat ctggtgcgcg cctttgcgtc
     1681 gcaaggggcg gagaaaagcc gtcccggcgt tgagggcgga gatccgttgc tcatggacgg
     1741 agattatatt cgaatcgcga cgttgcctac tcaggtggtc aacgtggtga gtctcgtcgg
     1801 ggcggtgaaa agtcctggcc cttatgaatt tcgggccggg atgcgcgtaa aagatatcct
     1861 gacgcccgag caactcacgg tggatgcgta tgccgatcgt gctgaaatcg ttcgtaccga
     1921 tccggccaca tatctgacga aggtgattcc cttcagtcct aaagcggtct ttgaaggtcg
     1981 ggaatctgac aatgttgcgt tgagccggct ggaccaggtg gtcatatcaa gccagatgcg
     2041 cgccccggcg ctggtgttgg tggagggaga ggttcggcga gcgggatact tcaccattga
     2101 gatcggcgag cggttgagct cggtgctgaa acgctccggc ggctttacgc ccaatgcgtt
     2161 tccgaacggc attgtcctgg tgcgggagtc ggtcaaggtg aagcagcagg ctgagctgga
     2221 tcggtttatc gcggcagaac ggcagcgatt aacggctcaa tcggccggaa tagctgccgg
     2281 caccgccggg ttgaacgtca tggcaggcgc cagtggagcc atggcggagc agcaggtgct
     2341 ggccttgcgg cttcagcaac tggaggcgac cgcatcacgg atcgagttgg gtcgtgtcat
     2401 cgtaagtttg gattcgatcg aacgtctgga agggacggag gacgatatca ttttggagtc
     2461 ccgggaccga attaccattc cgacaccgcc ccaaacggtt gggattattg gttccgtcaa
     2521 gagtcccact tcggtggtct atcgaccagg cttggatctg aatgactatt tgcgccaagc
     2581 tggtggggtg accgaagatg cgaacaagcg tgagatgtat gtgatgcggg ccaatgggac
     2641 gacggattcc tcctatctct cggcaaagga aatgcgcccc ggagatacca tcgtggtgcc
     2701 acaaaaaatc gaggcgcgtc cccctcagct cgcgttgtgg cagaccgtag ccagtatcat
     2761 tgggagtctt gctctgaccg ccgccggcat tgccgtggtt ggccgatagt cgatcggatc
     2821 cgtctatgga ttggccttcg gatagccccc acgccctttt ggatccgccg cgctccacgg
     2881 ttgaaaccct tcctgccgat cagcccgtaa cattgtttga ttattgggat gtcctggtgg
     2941 cgcgacgtaa gatgattgcc gcgttctttt tattcgggac gtgcctcacg ttagcgatta
     3001 gccttcttct cccgaaaatc tacgaatcaa cgtcatcggt cttgccacaa ttggaatcca
     3061 aagagggtgg ggccttggca gccctcttga ccgcaccggg tgccgccggt atggcacaga
     3121 atctcggtat tggcctgccc gggcttccga ccacaccgac cgatgtgttc gtttcgattt
     3181 tgaaatcccg tttaatggcc gacgaggtta tcaagaaatt cgatctcatg aatcgatatc
     3241 acgagtcgac gatggtcgat acgagaaagg aattggagga ccatctgcgg attactgtga
     3301 cgaaggagaa agtgatcaag gtgtcggttg aggatgaaga tcctcaagtg gctgcggata
     3361 tagccaattt ttatgtggcg aaccttgatc ggctgaaccg cacggtcacg gtcagcaagg
     3421 ccgggcaaaa ccgtgcgttc cttgaacggc gattggctga aaccatggaa agtatggcga
     3481 aggcggaaga ggcgctacgg gactttcagg ccaaaaacaa gacggtcgcc gtcgaggcgc
     3541 aagcgaaggt gatgatcgaa gctgccgcga tgattcaagg acagatcacg gcacaggaag
     3601 tccaattgca agtcatgggg gggtatctct cgcccgataa tcccgattta gccagaatcc
     3661 ggtctaatgt ggaagagctc aagaagcaac tggccatcat gggttcgggg aaagatgcaa
     3721 ggggtctctt gtccagtgat cggcttcatc cagccatggt tgcggtaccc gacctggctt
     3781 tgcagttcgg gagattgttc cgacaagtga aagtgcagga aacgctcttt acgctactca
     3841 cttcgcagca tgaacaggcc aagattgcgg aagctcgtga tacccctaca gtgcaagtgt
     3901 tggatccggc tgtcccggca gataaacgaa gtcgtccacg tgtcttgctc aacatagccg
     3961 tcgccggggt gctcgcactg atcatgggga cgttcaccgc gtatttcctc gactatcgtg
     4021 ctcgggttcg ccggatttca acacctgcgt gaaattgacg atttttcagt cgcaatggta
     4081 gaatccgcgc gatttctctg ctagaaggcc ggaagtctca gtcgttactc acattcacat
     4141 ttaccagaat aggagaacgg gatggctgtt ccagtctccc agatgtatac agtgaccaag
     4201 tacgtgttga cccagaaact ccggggggtc aaacggtatc cgctcgtgct catgctcgag
     4261 cccctgtttc gctgtaatct cgcctgtgcg gggtgcggga agattcaata tccggatcat
     4321 gtgctggata agcggttaac cccggcccaa tgctgggcgg ctgcagacga gtgcgaagcc
     4381 ccgatcatca gtatccccgg cggtgaacca ctgatccatc ctgaaatgcc ggagatcgtg
     4441 cgcggtctcg tcgaacggaa aaagtacgtg tatctctgca ccaatgccat tttgatggag
     4501 cggaagctcg atgagtatcc ggcctcaaaa ttcttgacgt tcagcgtcca catggatggt
     4561 ctgcgggatg agcacgatct ggcggtttgc cgcgacgggg tctacgacgt agcggtgaag
     4621 gccatcaaag cggcgctgaa gcgaggccat cgcgtgacga ccaacaccac gttgttcgac
     4681 gatgccaacc cggagcgcgt acggaagttt ttcgatgaga tgatggggct gggcgtcgaa
     4741 ggcatgatga tctcgccggg ctacagctat caaaaagccc cggatcaaca gcattttctg
     4801 aagcggagcc ggaccaccga gctcttctcc aagattctca gcaatcgaaa gcgtggatgg
     4861 cagttcaacc agtcgccctt gtttctcgag tttctcatgg gcaagcgcca gtatcagtgc
     4921 accccttggg gaaaccccac gtataacgtg tttggatggc agcgcccctg ctatttgctg
     4981 caagaaggct atgcttcaag tttccgtgag ctcatggaga agaccgattg ggactcctac
     5041 ggcaccgggc gcaatgaaaa gtgcgcggat tgcatggtgc attgcgggta tgaggcgtcg
     5101 gccgtggagg acaccttcgg gtcgctgtcc gggtttacga agaccgttaa gattaccctc
     5161 atgccgaacg ctcgatagcc ggtcgcaatc ggtatgagag tcgctatggt gaggtgttcg
     5221 gtcgcgagcc ggccgaatgc ttcaccgtca ccctgtgtaa gacgagaaga ttatgactga
     5281 cgcgaagtac cacgcgccgg agcccggcag ccttgaaggc cgggtctttc ggccgacatc
     5341 tctcactgat ctgagcgagg cgatcgaact ggcgtttgat taccgcggag atatcacggt
     5401 cgacctgaaa tccggcgggc aggtcaccgg ctacctcttt aatcgaaccg cgacgggaga
     5461 tcagccgacg atcgaagtat tcccttctac cagcagtggg accatgacca ttccctattc
     5521 agaggtgatg gctattgcct tcacagggga agacacggcc acaggaaaat cctgggaagc
     5581 ttggattgcc aagaaggagt cggagcgaca gaaggatatc gatcgggctg ccgcggaagc
     5641 caaatcgcgc ggtcatctct gagcgcttgt cttcttgatc cgctacgcat ttctcgtggt
     5701 gtgccgtccc cgttctcctc tgcgtcagtc gcgcgacttt tcttcacgcg cagccgcaat
     5761 ttccggtgcg tatttcctcg ttgatccctc cgtttgactc catccatttg ttgacaaaga
     5821 gggggggcta tgctagaaga gtcggcctca aatttggggc gagtccgtgt cgaggaagcc
     5881 tctcgtaaac aggctctggg cgagatgttt gtgaggccga aaaccagtcc ggcacggatc
     5941 gaacgtatgc gggggcggag agagattagt aagaataccg cccggcatgt cgtgcttgtt
     6001 tggggattga tcgcgacgct ctgcgtgccg tcggtcctgt ttgcgagtca cgccgccgac
     6061 catcgattca ccgtcgaagg gtttgtgtgc ggcaaagacg gccggcccgc tgtcaatgtc
     6121 gaggtgctgg tcaaggatac gcggatcacc gtcggccaga ccgtgacgac tgatggcgac
     6181 gggtactata aagtcactct gcatctgcat aatgataatg tcggcgaccc gctgttagtc
     6241 gaagcggccg gggagcagaa gaattcgaaa atccagttcg acccgaacga tctggagact
     6301 gaacgtaagc ttcgaatcga tttcggtagt gggtgcgagc gcgatcttgg tcctccgcag
     6361 tggttgttgt acgggctggg gatcgcggct gttgctattg tgggatggat tgggctaaag
     6421 atctcccgca agcggatgcg agaagagcag cggcgaaaga agggacaggg caagcggcag
     6481 aaatagggca cggtccgtgg ggcattgttc ctcgccggat cgaatagcaa gaagtaggcg
     6541 gggaagtcca aacgtgacct cgttgtattg tgagtcttga cgcttttgct gtggctgctc
     6601 gtggcaccgc agggaagcgt cttttttttc tgtcgatggc aataggtgtc tgcgcgtgaa
     6661 gcggcgcaga catgaagaaa ggagcgggaa cttttttatg aaacacgcag gcatgacgag
     6721 attggctctg atggtcggca ttcttgggtt tggttttggc gttgtcgggt gcggtggcgg
     6781 cggtgaaggc ggcggcgagg gtccggttgt tccgccaccc cctgctcctg ccgagtatgc
     6841 cgacaagcac atgcctgccg gctggtggac ggatccgaag atccttgaag agggcaagga
     6901 gttgtacatt ggcggaaaga atcctgacgt caattgcgcg agctgccatg gtaaggatgg
     6961 gaagccggtc aaggccggtg cccgcgactt ccgtaacggc gatcgtatga agatgtattc
     7021 ggattccgtc tggttctggc gcatctccga gggcgtgccg aatacgaaga tgaagccgtg
     7081 gaagagcaag ttgtccgaag aggatcgttg gaagattttg gcgtttgagc gctcgttcgg
     7141 cttgtccggc aagggttggg atgccaataa gaaggattgg gtgcctgctg accaggtgaa
     7201 gtaattcgcc tctgggttag ttcgagtcat gggtcaatcg gtaggaatga ggaggagcgg
     7261 cgagacatca tgaaaatctg gcagcgctgt ttgttggtta tgttcgcgct agtggcggta
     7321 ttgggaggag tggcctatgc ccaggctccc agtgcgcccc ccgtggagtt cccttacacc
     7381 gggaatcgca cggcggtatg gatcgtcgct caactccaca ttctttttgc cgggtttatt
     7441 ttgggcgctc cgattttcgt cgtaatttcg gagtggctgg gatatcgcaa gcaggatcca
     7501 cgctacgacc ggttggcgaa agaggtcacg aaggtcacgg tcatcctgta cagcatgacg
     7561 gccttgaccg gcggactctt tatcttcgtg ctgcttgcga cctatccgca gttcacgacc
     7621 tggctcatca atcacttctt cctgattttc gccgtcgtct atccgctctt gttcatcggt
     7681 gaaacgatcg ttctctacat gtacttctac acatgggatg cctggaaggg tgaaaagaag
     7741 ggccgccata ttgcattggg cgtgctgctc aatctcatcg gctcgatcac cctgtttgtg
     7801 atcgatgcgc cgacctcgtt catgaacact ccggtccggg ctgaaggtat ttcgccagcc
     7861 gagtttttgg cgactgcctc tctctgggac aaggtgttca actacagctg gatgccgctc
     7921 aatttgcacc gcctcgtcgg aaacgtcacc ttcggtggat tcgtggctgg tctcattgcc
     7981 gcctacatgt tcatggggtc caagaaggaa gaggatcgtg cctattacga ctggatgggc
     8041 tttgtcggca acatgatcgg tgtgggtgcg ttgttgttct tgccgttcat ggggtacttg
     8101 ctggcctatg agctctgcga ctacgacgcg tccatctgtc cgtacatgat ggctgatcag
     8161 ctgtcgatgt tcttcgagat gcaaggggcc atgatcggtc tcatcttcct cgccagtaat
     8221 tactacatct ggttgagtat gaagcggatc gagggtgtgg agcgggttcg tatgactgtg
     8281 gtggcgccga ttgttatggt gttactgccc attgtcatga cgaaggtcct gactgactat
     8341 cccgtgccgg atgccacctc gctggccttc ctgctgccgc ttctgctggc gccggttgtt
     8401 ctggggcgat ttatcccgct cacagtttcg tcgagcactg tcattaagat cggtttcttg
     8461 atggtcgttg tcggtaacgc tatctggatg acgccccacg gattcgtacc caccggcgcc
     8521 aagctggtgg cggaattgga gctgccgtct gactggaact tcctggcgct catgccggcg
     8581 aaaaattccg cggcgttcac gttggtcttc gtcaccgttg tgaactatgt catttataac
     8641 cgggcggttt ctcagggaac catcgtgtgg ggcaagatcg acttcgcttc gcaattcgtc
     8701 ctggtcttcc tcgcattcag cgcgatttgg accatgggcc tgatgggcgc cgtgcgctcc
     8761 ctgttgcgga agtacttcca tacgtacaac ctgttgccgg atttcacggc ggaatccttt
     8821 acgccaacgc tgtcttattc cgcgtggtgg atcaccggta ttacgatcgt cttttatgca
     8881 gtggtcagct tcgcgattat cgtgaccttg cgcccgtcag attcaaaggg tcacgcgcac
     8941 gaggggagcc cggttccggc aggggccaag tagggcggtc accatactgg gaagggcggt
     9001 aaacgagggc attcatggga aacattatta aaaagttggt cgtaggagtc gttgtcggcg
     9061 gaattctgtt cggcgccacc aacgcgctgg gctttccgtt cgtctttcag gcgctgtttt
     9121 tcggctacgc catgcttggc gccattgtct ttatgatcct cgattttccg acgctcaagc
     9181 cattcggcgg agtcaaggca gtcggggcat tgctcgtgtt ttatgccatt ctctccgtgg
     9241 tctacattgc gggcgcctcc atgtggccgc aatatgaccc ggaagatgaa aagggcaaaa
     9301 ttgaaaaaat tctcaagccg aagcgcgagc actacgaggc cggtaaggtc gaagtgttga
     9361 tgcagcgggc caaggctctg gatgaaaagg ccaaggagct gaccgctcgt ctgcaggcat
     9421 taggggcagc tcaagcgcct gccgaccaaa aggccggcgg cgaaagcgcg ccgaccgcca
     9481 ccacggcagc cgccagtggt gatatcgcca agttgggtga agagcaatgg cagctgcagg
     9541 aatgttacaa ctgccacaag ttgaatggcg aaggtggaaa gaaacgcggt ccggagctgg
     9601 acaacatcgg caaccttctg ccggcggcag aaatcgccag aaagattctc gatccgaaga
     9661 gctataaggc ggaagggttc gagcaggaat acgagaaggg caagatgccc gacaagtata
     9721 aggacctgat ggaaccgaag gacgtggatg cattggcgac ctggttggcc ggatacaaga
     9781 acgcttcggt gaataccccg aagccgatca agatgaagtg agcatcatgc agccgaaact
     9841 caaatcaaaa gttcgatgta cggacggtga agtcggagag gtgcgcaggg tcatcatgga
     9901 cccgctctcc cacgaaatca gtcatatcgt cgtgggcggg gggacggcag gcgtcatcga
     9961 gcgccaggtt ccgatgggtc aggtgctggc agtcagtgat gaggccgtca cgctccgcgg
    10021 cagctcggcc gagtttgccg cattgccggc cttcaagcgc gatgagtacg tgacgacgca
    10081 cgaggtggaa attgcccacc ttgaagaccg gatccatgtc acgccgggcg aagtcttggt
    10141 gccgtttcct gaactcgaac gcagtgtcaa gcggcggaca ttttttgcca atttcaccca
    10201 tgccatcggt tttctgattg gattcccgct cgctttcccg gtcctgcggt acctgatgaa
    10261 gccgatgtac tcgccgttcg acaacgaatg gttgaagatc ggcaactccg gaaagatcaa
    10321 gcaggacgat gtcggtgtcc aattcaagta caagcgcaag atcaaagaag cgtacatgcc
    10381 ggaacaggaa atcgataaga acgtctgggt cctgaaggcg acgccaaaag tgctcgagac
    10441 gatttatcag ggcaaggaca tggaattccg tgattcggcc ggaaaacata tctggacgaa
    10501 taagaaggat gttccgtttg tcgcctattc aggcaagtgt ccgcatctgg gttgtggatt
    10561 caagtggcgg acgcacaaaa ccctcggtca ggtctttctc tgtccgtgtc acttgagcat
    10621 ttacgacgcc gcggggaagg tcctggatgg cccggctcca cgaccgttgg accccctgcc
    10681 catcaaagtt accgcaacgg gtgagatcac cattattgat atggaattca aggcgggcac
    10741 taaggcccag gttcggattg tctaatggat acgactacgc agccgacgac cacgcagccc
    10801 tcagccattg aaaaagtctt cgcctttgtc gacgaacgcg tcgggttgaa gacgttgcaa
    10861 gccaaaatgc tcaacgagcc tgtccccggc ggctcacggt gggcctatgt ttttggctcg
    10921 gtgctgctct tcatcttcat catgcaggcg gtaaccggca ttctgttgat gttctattac
    10981 gtgccgaccg cggaccacgc gtacgccagc acacagtaca tcatccacac cgtggattat
    11041 ggatggttcc tcctgagtta ccacttctgg ggctccacgg cgatggttgt ctgcgtgttt
    11101 gcgcacatgt cccaggtctt tctttggggc gcatacaaaa agcctcgcga actcatctgg
    11161 ttggtcggtc tcgccctgtt cggcatcgtg atgggattcg gcttcaccgg atatctgctt
    11221 ccctgggacc agcgggccta ttgggccacg accgtcggcg tcgaaatcat ggacaagacg
    11281 ccgttgctgg gcgacttcat ggcccggttc ctgaagggtg gggcgacgcc gggacagatg
    11341 acgctgagcc gcttcttcgt catccatgtc atggtcttgc cggctgcgct catgggtctg
    11401 gccggtttgc acctcttcct gttccggaaa gccggccccg ccggtccgtt ccgtggcagc
    11461 gtcgaggaga tcaaagccaa gaccgactat ttcttcccgc gacaaatctg gaaagacatt
    11521 gtcggaatgg tggccgtgtt cctctgcatt tgcagcttgg ccttctggga accgatcgtg
    11581 ctgctcgagg aggcaacccc ggatcccggt gattaccatc cggaacctga gtggtacttc
    11641 ctgtttctgt tccagctgtt acgtctgaaa gtcttcgcgg gagaattcgg acagttcctg
    11701 ggcgcgattg cgttgcccgg ggtcttcatg gccttgctgg cggccttgcc ctttattgat
    11761 cgcgacccag aacgaaatat tttcaaacgg ccgattgcct tgatcagctg gattgtagtc
    11821 atggcgagta tcctcatttt caccgtggcg gcgatcatca atcgcgaatt tttggaatag
    11881 ccggagggtc ttcgtcacat gactggtcga gagacgatgt cgtcatttaa attggggctg
    11941 agcattctct ggcctgcctg ttggaccgcc ctgccgctca agatggcatt cgccatgttg
    12001 tttatggcta tgggcaccat ccatctggag accaagctcg ggattacttt cctgatgctg
    12061 ctcatgagcc cggtgagtgt gtttgcattt ttcgtcattt ccttgggcgt cggatttcac
    12121 tttggtgaag gcaccgggct tcccttactc ttcctggtat ccatccccat tgatatctgg
    12181 gcgctgggcc tcgtggcgcg taccgtattt ctggagcgcc tcaggcttga accaccggat
    12241 tcactcgggt tggggttatg ggttcgtttc gctattgccg gggccgtata tctgcccctg
    12301 ctctgggtgg tggagggagg agccacggat ctcgcccgtt cgatcgtgaa ggccattctc
    12361 gacatggaca tgctgaaggg acttccagtg gctgaacgca tcggcctgga gtttaccgcg
    12421 tggggcagtg cctctctggt cgtgttgatt gccctgacct ttatcggact gaccattctc
    12481 ggcaagttgg tcgaaggaaa gacagccgga gcccagccgt caggggacag ttatcagggg
    12541 ctgatctctc ggtgggatat gattcgcgtg ccggcggatc agagtctgat gctcaccgcc
    12601 tttacggcag ctggggcggt cctgagcgtg ttgttctgga tggtgcttcc agtctccact
    12661 ccacatcctc acgaatgctg taagccagcc agcgttgctc ctgttgcacc attcgacccc
    12721 caaaaatctc tctccaaggg ggaaaaggtg ttgaaggacg cggaggtgaa gatcgccgcg
    12781 ttagaacaga agacggctga agacgagaaa gataagcaaa agggcggcaa ggaaaaagcc
    12841 ggtgtcaagg acagctccgc caagagcgac ggcaaggctt cacaggtaac agccgggaaa
    12901 ccggcgggaa gcaaatgaca tcatggcgaa cgacgaggtg agaacaatga ggaaccaagg
    12961 gcggactatg gataatcagg tgcgccacat ggcaggccgt atcgcgttgc tggccggatg
    13021 cgcggcgatg ctcggctgga tcggcttgcc ggacacggct atggctcagg acgcggctgc
    13081 tcaagcgccc accgcctatc gtgacatccc ctatgtcgga agccgcaatc tggtctggat
    13141 catcgcccag ttgcacctcc ttctcgccgg attcgtgctt ggcgtaccca tttttgcctg
    13201 gttgtgcgaa gtggtcggtt ggaagtccgg cgacaagcgc tacgataagc tcgccaagga
    13261 gttcaccaag ctcctgacgt catcctacgc cactaccgcg ttgttcggtg gcatcctgct
    13321 gttcctgttg atcggcttct acccgaagct catggcctat ttgaccgaca ttttcttccc
    13381 atccttcctc gtctactgcg gcctcttcct cgtggaaacc gcgaccctct acctctattg
    13441 gtacggctgg gatgcgatgt ccgagggaaa tgggaagaag ttccatatct ttttgggctt
    13501 cctgctcaat gtgttcgcct ttttcatcat gatcgttccg aactcctggg cgaccttcca
    13561 ggcaagcccg gtcgtcattg ccgaaggcac cgacttcgag cgggcctggg cggcgacctg
    13621 gaatccaacc tggtggccgg tgaatattca ccggatcatc gccaacgtgg tgctgggagg
    13681 ctacatttgc ggagcctacg caggtattcg gtacctgtcg gccaagagca cggaagaacg
    13741 gtaccactac gattggatgg gctacgtcgg caacttcatc ggcgtcttcg gcttgttgcc
    13801 cctgcccttc gccggctatt ggttgatgcg tgaaatctac cagtacaatc aacagatggg
    13861 catcacgctc atgggcggat tcctctcctg gttgttcatc ctgcaagcca tgttgatcgg
    13921 tgttctcttc ctcggctcca actactattt ctggatgggt attacgcatc gaataccagg
    13981 ctcggagggc caatatcgca aaccgattat ggcgatgctg atcatcctcc tgatgtgtct
    14041 tgcggtgtgg atgacacccc actccctcgt cgcaagtttg gaagaagcgc aaaagatggg
    14101 cggcacacac cacccgctcc tcggcgtgtt cggcgtcatg tcggccaaaa tgacggtatc
    14161 gaacctgatg gtgctcgtga cgtttatgag cttcatcatg tactggcgcg caggcaaaga
    14221 agacactgcg ggatgggcca aagtggctaa gtctgtgatg ggcgctgtgc tggtccttgc
    14281 cggactcgcg gttatcgtgc tcggtgtgtg gggctacttc gtaccggcca ttattcgtat
    14341 caattacttc tcgacgtccc aggtcgcgat cgtcatcttc gtcatgttga ccatcactcc
    14401 gttgacggcg ttattgctca agagcgctaa gaccaccact gagatggtgt ggggccgtat
    14461 gccgcctcgc gccggctact cactcgtctt gaatgccgtc atggtcatcc tcctgatgac
    14521 cttgatgggt tatgcccgct cctcgtcgcg tgtccattgg catgtgtacg gtgtgatgcg
    14581 tgactcttct caatatgcct tctcgcccgc gctcgggtac gcggccgccc tgatggccct
    14641 ctgtaccttc ctgttctgca tgctggtcgc cttcattttc tgggtcgcca cgatgggtga
    14701 caaggcgaaa gctgcggcga gcgcgaaggg tgctccggaa ccaggtcaca ttcctgccat
    14761 ggcaggcgga tcgcccgcac tggatggtcc ggcgagcgat gcaagtgagg gaaaccgtcc
    14821 ggtctgatcg ggaagatgat cttcttctgg taaccagggg cgggtcgtga tcattatcct
    14881 tagttgagga cttatgagcg aagtagtcaa actgcagcta atcggtctgt gcgttgtcgg
    14941 acttggaacg gtcatccttt tgttcatcaa ggggcaattt ctccgagtca tcggatttgt
    15001 cgcgatcgtg ttgggcttat ttgccctggt ggcgttggcg gtgccgcaga tggcgtcgtt
    15061 acccccggcg gaggagagca tcaatatcgc cgacattaaa acggcaacgg acatggcgac
    15121 gatcggtcaa aaaatatttt tcagcaaagg tcagtgcgcc ctctgtcatt cgatcgggcc
    15181 gagcgagtca gcccgctgcc cggacctaaa aggcattggc gccaaattgt cgcgggaatt
    15241 catctttgaa agtctgacgg aaccgcaggc gtatctgtac ctggactacc gacatgaagg
    15301 tgtcccgaag gaatatccgg cgcgtatgcc gtacatcaat agaaatccca tcggtctctc
    15361 gaagaacgag atcctgtcgg tcattgcgtt cctgcagcaa atgagtggcg agccgatcag
    15421 cgtgagtcct tcggaacttg acatcccacg tgccaccccc gcaccggtga aggccgcaga
    15481 tgccggcacc gtggcagtgg cccaagcacg ataagttatt ggcggtgaag tagaggagga
    15541 aggtatggga ggcgtactca tcagaccaat catactgacg gtctgtatct atttgttctt
    15601 gaaattcatt gtcccggtgt tgccgcacag cgcgccgctg ccttcgagct tgatttttct
    15661 gtacctgatg ctggtgatgt caggctccgt gttatttgcc accctgagcg gtgaatcgaa
    15721 agatgccttc tttcaaccca tcctccgctt cctgactggg gaaagtggcg gagcgctcag
    15781 tagcgcccga tatctcgtgt tggcattgtt cccgttgctc gtcggatggc aggcctacgg
    15841 gagcacggcg tcgagtgacg cgcccccggg tgaaaatcgt acgattcacc ccgctcctcc
    15901 cggcgaatat accggactgt ctaatccggt acccaagacg ccggagaata tcatgtatgg
    15961 caagggtctc tacgcctcac gctgtgcgcc ctgccatggc aactttgatg gtaagggttt
    16021 cgcggcagcg ggatttacgc ccccaccggc gaactttaag gatccgacga cgatcgccat
    16081 gctacaggaa agctatctgt tctggcggat caagaaggga ggcgtcggcc ttcctgtcga
    16141 agggatgcca tggaaaacgg ccatgccgcg atgggaattg gaaatgtccg acgaggatat
    16201 ctggaaagtt attatgggcg aatatgacgg agccggacag aagccaagaa cctgggatga
    16261 gtccgagtaa tttctccgat cagagactgc tgagcaatta aggggaacgt atggcacgag
    16321 tgaggagagt aggaaagaga tg
//
LOCUS       DAOQPD010000090        16259 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1799_length_16259_cov_22.549864, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000090 DAOQPD010000000
VERSION     DAOQPD010000090.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 16259)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 16259)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16259
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1799_length_16259_cov_22.549864"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..289)
                     /locus_tag="PK063_16065"
     CDS             complement(<1..289)
                     /locus_tag="PK063_16065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98617.1"
                     /translation="MIFLRRQLPLLITMITGLVMAAQYYVPHPASEQLLTTVTKWLQI
                     IGGFALVLGITSLFHVHAAKIRRKEAGWAYSLVLYVGMLGTIIVGLWNNGKE"
     gene            complement(286..1524)
                     /locus_tag="PK063_16070"
     CDS             complement(286..1524)
                     /locus_tag="PK063_16070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98618.1"
                     /translation="MLRRILILVFVISLPAIMPTLAPAQAMPQQLRVIDTPSDGGGSL
                     TVLWAPSATDSATTKYQILVHEGGLPQDPTAWKVVAEFPANTRYVREGKSAWWTRSGD
                     PNDHLFLIKNGKGLEVKSGQPYAVTVASVNGKERLIAPPVIASAEPNWMNWNQVNNLV
                     LALMFGAIVFYAINLAKRKDIFLRRIPGLDAVDEAIGRATELGKPVLYMTGAHDMNDP
                     STIAAAVILGRVAKKAASYETELLVPHREPITMAVCQEITKQAYMEAGKPDLFKDDAN
                     FFITSDQFSYTAAVDGIMLRRKPAANFFMGSYFAESLLLTETGASTGAIQIAGTDSDH
                     QLPFFVTTCDYTLIGEELYAASAYLSKEPIQIGTLRGQDLGKAFILSVIGIGTLLATV
                     AVLTGNGWAQPLLDLFKDLK"
     gene            complement(1530..2657)
                     /locus_tag="PK063_16075"
     CDS             complement(1530..2657)
                     /locus_tag="PK063_16075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98619.1"
                     /translation="MAHSYTPGLTVTERTTVRRRRILPLPGAVLVQVGDAVRADTAVA
                     RAELPGKVVPLNLANQLGIAPDEINDYLVKKEKDSVQKDDVLAENKPFIKWFKTEIRS
                     PITGKVESVSTITGQILLREPPRVLELRGYIDGVVAEVHPEQGVTVESTCSLVQGIFG
                     IGGETSGELVMGVKAPDQPLLPEQLNPSMKGKVVVGGAFLSAATMTRAKELGIVGLVV
                     GGIHDKDLRALLGYDLGVAITGTEQVGFTLILTEGFGTIPMAPKTFALLSAHAGQKAS
                     ISGATQIRAGVIRPEIIIPHSGPAAVTKLPKAEREGIQLGDPVRIIRDPLFGKIGAVS
                     GLPSELRAIPTESEVRVLEVRFPDGTTTVVPRANIEVIEGA"
     gene            complement(2853..4706)
                     /locus_tag="PK063_16080"
     CDS             complement(2853..4706)
                     /locus_tag="PK063_16080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate mutase L"
                     /protein_id="HMZ98620.1"
                     /translation="MTAAHQSPATSNPAQPLNVIVATDCGSTTTKAILIEKVGNEYRQ
                     TYRGEAPTTVEAPFEDVTRGVLNAIAEIEELSGRTILDGDRIITPNQAAQGDPQRGVD
                     IYVSTSSAGGGLQMMVTGVVQNMTGESAQRAALGAGAIVIDVLASNDGRLPYEKIERI
                     RTMRPDMILMSGGTDGGAVTHVVEMAEYIAAAEPRPRFGSTYRLPLVYAGNKDAQPQV
                     KTILGEKTALEFADNIRPVLERENLAPARNKIHDLFLEHVMQQAPGYKKLIEMAGAPI
                     MPTPAAVGVIMETIAKREGINLIGVDIGGATTDVFSVFGGLFNRTVSANLGMSYSISN
                     VLAEAGLENIMRWVPFTIDEQTLRNRIKNKMVRPTTIPQSLDELQIEHAIAREALRLA
                     LIHHKSLATGLKGVQQERTISDVFEQRTSGKTLIDLLKLDLIVGSGGILSHAPRRIQS
                     MLMMVDAYEPLGVTTLSVDSIFMMPHLGVLSTVNEQAATDVFVRDCMVYLGTCIAPIG
                     QGKDGERCADYEVALPDGRIEKGTLTFGDLKLFSLTRDQQATVTLQPSKQVDLGEGPG
                     QSFTRTVKGGVVGLMLDGRGRPLQLPTEQAARVALLTRWYQAVGLYPTGSS"
     gene            complement(4703..5077)
                     /locus_tag="PK063_16085"
     CDS             complement(4703..5077)
                     /locus_tag="PK063_16085"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98621.1"
                     /translation="MAVFSSGLFSRRTHDLRAGLRHAFALRSDQPAFTTEDLALLERI
                     ADAIVTRRMAVPATLFLESMGPMNFLGSQALHFLAPLVECVFSSSELAQIARLLERRD
                     SLQRLTALIEAKAAASKGAPAR"
     gene            complement(5214..5852)
                     /locus_tag="PK063_16090"
     CDS             complement(5214..5852)
                     /locus_tag="PK063_16090"
                     /inference="COORDINATES: protein motif:HMM:TIGR00758.1"
                     /note="This protein belongs to the uracil DNA glycosylase
                     superfamily, members of which act in excision repair of
                     DNA. However, it belongs more specifically to UdgX branch,
                     whose founding member was found to bind uracil in DNA
                     (where it does not belong), without cleaving it, appears
                     to promote DNA repair by a pathway involving RecA, rather
                     than base excision; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UdgX family uracil-DNA binding protein"
                     /protein_id="HMZ98622.1"
                     /translation="MRRSLRSAASFLPSKLTLPTLRNAAASCTGCDLYKTATQTVFGE
                     GPARATLLLIGEQPGDQEDVAGHPFVGPAGRVLDKALEEAGIARSDVYVTNAVKHFKW
                     EPQGTRRKHKKPSAAEVAACRPWLEAEIQVLEPRAILCLGVTAAQSVFGKSVRVNELR
                     GRPLTAPLGKTVFVTTHPSAILRGPDPAQREEDYRHFVGDLRLIAEYLQQRR"
     gene            complement(5804..8899)
                     /locus_tag="PK063_16095"
     CDS             complement(5804..8899)
                     /locus_tag="PK063_16095"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HMZ98623.1"
                     /translation="MTTTPFVHLHVHSDYSPMRGVSSLETLCRSAKRQGLGALAVTDT
                     NGLYGAIRFIEEARHEGLRPILGAELTTDTHRALLWAKTPGGYANLCRLLSARHCEPS
                     FAFIEAVARYRDGLIIATDDQAALEAWLADDSQDLYVELTPGPAMQKTLEMSRRIGVP
                     SVATNRVYFARADDFATHRLLRAIALNQTFSRLPQAACCNPEQWLVPPERMAAAFPHV
                     PEALANSVRIAEACYSDWHFGDTIFPAFRELTDNAAFLTLKDDTYAGAQERYGLLSEE
                     VRARIEKELAVIRAKRFAHYFLIVKEILTQEPLTCGRGSVAASIVSYCLKITHVDPLK
                     HHLFFERFLNPGRKDPPDIDIDFPWDKRDGVLNWVFRQYGERQAAMVANQNSLGFRAA
                     IRETAKVYGMPADEIGTMSARVSRQQAILDFSTPPTPEQWLNRLSRTLRLKAPWPEIL
                     EQALRAQNHFRHLSMHCGGVVIVPDEIRRYVPVEFTAKGLPVIQWEKDQAEESGLVKI
                     DLLGNRSLAVIRDALDAIARHTGRTIEYASWDPLHDHATQDLIRRGDTIGCFYIESPA
                     TRLLLRKLWSGMPPDRLAVADVFEYLVMVSSLVRPAAITFVHDFVRRAHGHPYEPLHP
                     LMDNMLQETHGIMVYQEDVTKVAMALADFPLEDADQLRKVISKKHKSRQLRDYYQQFC
                     RGAAKNGAAPDTIDKIWTMIMSFAGYSFCKPHSASYAQVSFKSAYLRAHYPAEFIASV
                     ISNQGGFYSAFAYVSEARRMGLAILPPDVNASDWAYRGEGDRLRIGLMQVKTLQKELG
                     ERIVENRTEAGPYRSFEDFRRRVNLPPTQARALIRAGCCDSLAGELTRPALLWRLYAE
                     EQRHAGPLPIPEDYTDTHKLTHEIESLGFLTNRHPLTLYRHSIERLRPVPAAHMHRHV
                     GQRITMVGWLVTEKSVETRRGQAMEFVTLEDTTALYDATLFPNVYRRCHQFLAPNRAY
                     LVRGLVEAVFGVVTLTVTELQPLDAEPVREPAWNGARDAWYGESCDDRSDQPPPFSLP
                     N"
     gene            complement(8896..10077)
                     /locus_tag="PK063_16100"
     CDS             complement(8896..10077)
                     /locus_tag="PK063_16100"
                     /inference="COORDINATES: protein motif:HMM:NF013015.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98624.1"
                     /translation="MHRDIVCLQIPSFEIVLARTHEASLRHRPVALAPVHTPRGLVRE
                     VSQEALDDGVLPGMSVELARQLCPGLRVIPPDSSRTQAAHRELQQAIMPFAPVWESIQ
                     PGSLFLDLTGTQRLFGRPIDTAARLERELTVKWGWHSQIGVAMNKLVSHLAATTLEKP
                     PQMRSIYSGSEQAFLAPLPATLLPGLNRLQASHILRRLDDLNLRTLGSIADVSLVQLE
                     AVLGTAAVVLHDWAMGIDHSPVRPSVEQPQIEQSLTLNPDEIDDHLILGRLSHLLERI
                     CARLRQQRRMCRRLSLALRHSDHAERMAQHILPYGTYWEADLQPVLAQLFARCFRRRV
                     RIQRIIVRADCLEPLAEQLRLFDESTIAVQPASHRISLVLDAIRAKFGERAIAWGKTL
                     P"
     gene            complement(10263..10706)
                     /locus_tag="PK063_16105"
     CDS             complement(10263..10706)
                     /locus_tag="PK063_16105"
                     /inference="COORDINATES: protein motif:HMM:NF024901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4124 domain-containing protein"
                     /protein_id="HMZ98625.1"
                     /translation="MIWLYLLPFTFLVLLHSNPVEAKIYSCEGPNGGTMLTDQPKGKR
                     GCTVVKTPSPSPPGGFTPPVEEAPAAPPDLQPNTFLPSQPVSPIHQPNPRPLDPIDKL
                     QPPTGSQAGGEKAAPEAQRCSPRVNPLNPFAGMNCSPTADETKKP"
     gene            complement(10834..11187)
                     /locus_tag="PK063_16110"
     CDS             complement(10834..11187)
                     /locus_tag="PK063_16110"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98626.1"
                     /translation="MPESAGEKHQLAGFDARERGFNRPVELVRTASGYQATLRYESTQ
                     VVTPDAPTTADALQHMIRILQEQGYTQLRSQQSYRDGVYLGSQELWIEYPDRQPEPEV
                     GLLGLMKKWLGRSPG"
     gene            complement(11193..11561)
                     /locus_tag="PK063_16115"
     CDS             complement(11193..11561)
                     /locus_tag="PK063_16115"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98627.1"
                     /translation="MADNQLTPKHIEIAETFVRLYVFLTQYIDRCEDEAARKEYPEAE
                     LQKHLGETRAKMVDILKVNPVVKGKVEKECERVLALGSKCLMGGTEKVAALDVLGAER
                     VILKNKTIALSDLLAVYRAL"
     gene            complement(11635..11940)
                     /locus_tag="PK063_16120"
     CDS             complement(11635..11940)
                     /locus_tag="PK063_16120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rieske (2Fe-2S) protein"
                     /protein_id="HMZ98628.1"
                     /translation="MGELIRIAGTADVKPGAGMVAEVNGKAIAVFNVDGTFYAIDNTC
                     VHRGGPLGEGDVVGDVVACPWHNWEFNVKTGACINNPSAKVTAYEVTVEGTDIKVRL"
     gene            complement(11968..12864)
                     /locus_tag="PK063_16125"
     CDS             complement(11968..12864)
                     /locus_tag="PK063_16125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HMZ98629.1"
                     /translation="MAEEPGGAPHQDEAAARPNIIPGVKHVVAVSSGKGGVGKSTVSV
                     NLAVALALTGAKVGLLDADIYGPNIPMMMGVEKTPEQKDGKIAPAESHGVKLISMGFF
                     VPEDTAVVWRGPMVHTAIQQLFRDVLWGELDYLLIDLPPGTGDAQLTLTQLVPLSGAV
                     TVTTPQEVALHDVRKGMMMFQKVNVPLLGIVENMSFFVCGHCGERTEIFSHGGGERAA
                     EKLGIPFLGRVPIDPVIRAGGDTGNPIVVAKPDSPQAQAFRDIAAKLAAALQTGGVSA
                     TKSRIESLLDKIKRPAADRKPD"
     gene            complement(13137..13970)
                     /locus_tag="PK063_16130"
     CDS             complement(13137..13970)
                     /locus_tag="PK063_16130"
                     /EC_number="1.14.19.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016717 - oxidoreductase activity, acting
                     on paired donors, with oxidation of a pair of donors
                     resulting in the reduction of molecular oxygen to two
                     molecules of water [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA desaturase"
                     /protein_id="HMZ98630.1"
                     /translation="MADSSTQSVCWGTVALFTALTILTFVGVPLFAYYYDYTVLDWTL
                     LAILYVVTGMGITVGYHRMITHRSFESHLWVKICLLIMGGWAVQNSALLWCADHIRHH
                     AHTDEEADPYNASKGFWHSHVGWLFINTPYREDRFAAKLRTDPMILWQHRYYWVIVAS
                     GLLLPFAAGYLNGGLMSGLGCFLLAGVLRTVLVLNSTFTINSLCHMVGTQPHGTQDSS
                     RDSWLISFISFGEGYHNYHHTYSHDYRNGSKWYNFDPSKWLIYTLSLVGLTYNLHRER
                     T"
     gene            complement(14149..14727)
                     /locus_tag="PK063_16135"
     CDS             complement(14149..14727)
                     /locus_tag="PK063_16135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98631.1"
                     /translation="MHSTSKVICQMPPMPIETTHELIEIILAKWEGAIGEDYLGYKGH
                     VYRMFNFCLALHPCTEEENTKLAIAACFHDMGLWPDRTLDYLPASISHAAQYLSDSGR
                     EEWSEEMALMIGMHHKVRAYPDRRYPLVEVFRKGDLVDVSLGLLSCGIPRSYITDVKN
                     HFPNHGFHTFLLKTGRAWVSRHPFNPAPFMRW"
     gene            15135..15962
                     /locus_tag="PK063_16140"
     CDS             15135..15962
                     /locus_tag="PK063_16140"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98632.1"
                     /translation="MLGTVTRKVLKTILSDTARQRILTVERVHREGGLFDADSIFYRC
                     VGTVVTWGTGSRVHSGPFAGMRYIQHALGVHSSAYCPKLLGTYEQELHPLVEALRTGH
                     PYAHVINIGAGEGYYAIGFARCLPQSRVTAYEADAESRVILGRMAEINGVAPRLTIRE
                     SCTPSGLQAAMAQPGKTLIVCDVEGAEQELLDPVAIPALTRADILVELHDFLIPGISG
                     VIRKRFENTHQITEIPALPRQLADWPLSLSLPKVYRRTALSEYRPGGMCWFWMKARG"
BASE COUNT         3077 a         4750 c         5104 g         3328 t
ORIGIN      
        1 tttccttgcc gttattccag agtcccacga tgatcgtgcc gagcatgccg acataaagca
       61 ccaggctata ggcccacccg gcttccttcc gccggatctt ggccgcatga acatgaaaca
      121 ggctggtgat gccgaggacg agcgcgaagc cgccgatgat ctggagccac ttcgtcacgg
      181 tggtaagcag ttgttcggag gccggatgtg gcacgtagta ttgggccgcc atgaccagtc
      241 ccgtgatcat ggtgataagc agcggcagtt gtcggcgaag gaaaatcatt tgagatcctt
      301 aaacaggtcc agcagcggct gcgcccaccc gttcccggtg agtacggcga cggtggccag
      361 cagcgttccg atcccgatga cgctcagaat gaaggccttg ccgagatcct gtccgcgcag
      421 cgtgccgatc tggatcggct ccttcgagag gtacgcgctg gcggcgtaga gttcttcgcc
      481 gatcagggtg tagtcgcagg tcgtcacgaa gaacggcaac tggtggtccg aatcggtgcc
      541 ggcgatttga atggctcctg tgctggcgcc ggtttccgtc agcagcagcg attcggcaaa
      601 gtacgagccc atgaaaaagt ttgccgccgg tttccgccgg agcatgatgc cgtcgaccgc
      661 cgcggtgtag ctgaactggt cgctggtgat gaaaaagttc gcgtcgtcct tgaacagatc
      721 cggtttcccc gcttccatgt atgcctgctt ggtaatttcc tggcagaccg ccatcgtgat
      781 cggctctcga tgcggcacca ataattccgt ttcgtaggag gcggctttct tggcgacacg
      841 tcccaggatc acggcggcgg caatcgtgga gggatcgttc atgtcatgcg cgccggtcat
      901 gtacagcacc ggcttgccca attccgtggc ccgcccgatc gcttcatcga cggcatccag
      961 accgggaatg cggcggagaa agatgtcctt ccgcttggcc agattgatgg cgtaaaacac
     1021 gatcgcgccg aacatcaacg ccaacacaag attgttgacc tggttccagt tcatccagtt
     1081 gggttctgca gaggcgatta cgggcggcgc aatcaatcgt tccttcccgt tgaccgacgc
     1141 gacggtgacg gcatagggct ggccggattt cacctcgaga cccttgccat tcttgattag
     1201 aaagaggtga tcgttcggat cacctgatct cgtccaccag gccgacttgc cctcgcggac
     1261 gtagcgcgta ttggcgggaa attctgccac gaccttccac gccgttgggt cctggggaag
     1321 gccgccctca tggacgagga tttgatattt cgtggtggca ctgtcggttg ccgagggagc
     1381 ccagagcacc gtgaggcttc cgcctccgtc gctgggggta tcgatcacgc gaagttgctg
     1441 cggcatggcc tgcgccgggg cgagcgtcgg catgattgcc ggcaagctga taacaaagac
     1501 caggatgagg atgcggcgca gcaagagggt caggctcctt caatcacttc gatgttggcg
     1561 cgcgggacca cggttgtcgt gccgtccgga aatcggactt cgagcacgcg gacttcgctt
     1621 tcggtcggaa tggcgcgcaa ttcagacggc agcccggaga ccgcgccgat cttgccgaac
     1681 agcggatcgc ggataatccg gaccggatcg ccgagttgaa tgccttcccg ttcggccttg
     1741 ggcagcttcg tgaccgcagc cgggccgctg tgtggaatga tgatttccgg gcggatcacg
     1801 ccggcgcgga tctgcgtagc tcccgagatc gacgcctttt gtcccgcatg ggcggagagc
     1861 agcgcaaacg tcttcggtgc catgggaatc gtgccgaacc cttccgtcag gatcagcgtg
     1921 aagccgacct gctccgtgcc ggtgatcgcg acgcccagat catatccgag caacgcgcgt
     1981 aaatccttgt catggatgcc gccgacgacc aggccgacga tcccgagttc tttcgcgcgc
     2041 gtcatcgtgg ccgccgagag aaacgcgcct ccgacgacga ccttgccctt catggatggg
     2101 ttgagctgtt ccggcaggag cggctgatcc ggcgccttca cacccatgac gagttcgcca
     2161 ctggtttctc ccccgatgcc gaagatgcct tgcacgaggc tgcaggtgct ttccaccgtc
     2221 acaccctgtt cgggatgaac ctcagccacg accccgtcga tgtacccgcg caactcgagc
     2281 actcgcggcg gttcgcgtaa caggatttgt cccgtgatcg tggacacgga ttccaccttg
     2341 cccgtgatgg gggatcgaat ttccgtctta aaccatttga tgaagggttt gttctcggcg
     2401 aggacgtcgt ctttctggac ggagtccttt tcctttttga ccagatagtc gttgatctca
     2461 tccggtgcga tgccgagctg attcgcaagg ttgagcggca ccacctttcc cggtaactca
     2521 gcgcgggcca ccgcggtgtc ggctcgcaca gcatcgccga cttggaccaa gacggcaccc
     2581 ggcaaaggga gaatacgccg gcggcggacg gtcgtccgtt cagtgacggt caggcctggt
     2641 gtgtaactat gtgccatatg gtcggttgct gaacacgcct tgcagtgtcg ttctcagttg
     2701 ctcattcccc tcgccgtaca tcaagagtac gactcggggc tctggcgcct tgcggccttg
     2761 ctgcaagacg tgttgagcaa cctcttaaag ccaatgatgt ccattgcggg cttggccgca
     2821 tgttgtctct cgtcatgagc catacgcgct cactatgagc tccccgtcgg gtacaacccg
     2881 acggcctgat accagcgtgt cagcagggcg actcgcgcgg cctgctccgt gggcaactgc
     2941 aagggacggc cacgcccgtc cagcatgaga ccgacgaccc cgcccttcac cgttcgcgtg
     3001 aacgattgtc ccggcccttc gccgagatcc acttgtttcg acggctgcag cgtgacggtt
     3061 gcctgctgat cgcgggtcag actgaataac ttgagatcgc cgaacgtcag cgtgcccttt
     3121 tcgatgcgtc catccggcag cgcgacctcg tagtcggcgc atcgctcgcc gtccttgccc
     3181 tgcccgatcg gcgcgatgca ggttcccagg tacaccatgc agtcgcggac gaagacatcg
     3241 gtggccgcct gttcgttgac cgtggagagg acgccgagat gcggcatcat gaaaatgctg
     3301 tccaccgaga gcgtcgtgac gccgagcggt tcgtaggcat cgaccatcat caacatggac
     3361 tggatgcggc gcggcgcgtg tgacaggatg ccgccgctgc cgacgatcaa atccaacttc
     3421 aacaaatcga tgagcgtctt gccggaggtg cgttgctcga agacatcgga gatggtgcgt
     3481 tcctgttgga cacccttcaa cccggtcgcc agcgacttat ggtggatcaa tgccagccgt
     3541 agggcctccc gcgcgatggc atgttcgatc tgtagctcat cgagcgattg cggaatggtc
     3601 gtaggccgca ccattttatt cttaatgcga ttcctgaggg tctgttcgtc gatggtgaac
     3661 ggcacccagc gcatgatgtt ttcgaggccc gcttccgcca gcacgttcga gatgctgtag
     3721 gacatgccga ggttggcact gactgtgcga ttgaagaggc cgccgaagac cgagaacacg
     3781 tcggtagtcg cgccgccgat gtctacgccg atcaggttga tgccctcgcg cttggcgatg
     3841 gtctccatga tgacgccgac cgcggctggc gtcggcatga tgggcgcgcc ggccatctcg
     3901 atgagtttct tgtagcccgg cgcctgctgc atgacgtgtt cgagaaacag gtcatggatc
     3961 ttattgcgcg ccggcgcgag attttcccgc tccaggacgg gccggatgtt gtcggcaaat
     4021 tccagggccg tcttctcgcc gagaatcgtt ttgacctgcg gctgcgcatc cttgttgcct
     4081 gcgtagacaa gcggcagccg ataggtgctc ccgaagcgcg gccggggttc ggctgcggcg
     4141 atgtattcgg ccatttccac gacgtgggtc acggcgccgc cgtccgtgcc gccggacatg
     4201 agaatcatgt ccggccgcat ggtgcgaatc cgttcgatct tttcgtaggg caaccgcccg
     4261 tcgttggacg cgagcacgtc gatgacgatg gcaccggcgc cgagcgcggc gcgttgggcg
     4321 ctttcccccg tcatgttctg caccacgccc gtgaccatca tctgcaagcc gccgccggcg
     4381 ctgctggtgg acacataaat atccacgcct cgctgcgggt cgccttgggc cgcctggttg
     4441 ggcgtgatga tgcggtcgcc gtccaggatc gtgcggccgg aaagttcttc gatttctgca
     4501 atggcgttga gcacgccgcg tgtcacgtcc tcgaagggcg cttccacggt cgtgggagct
     4561 tcaccacggt aggtctgacg atattcgttg ccgaccttct cgatcaggat ggctttggtg
     4621 gtggtgcttc cgcagtcggt cgccacgatg acgttcagcg gctgcgcggg attcgatgtc
     4681 gcgggagact gatgcgctgc cgtcatcgag ccggcgctcc tttggacgct gcggccttgg
     4741 cttcgatgag cgcggtgagg cgttgtagag aatcccgtcg ctccaggagg cgggcgatct
     4801 gcgcgagttc gctgctgctg aagacacatt cgacgagagg cgccaggaag tgcagcgcct
     4861 ggctgccgag aaaattcatg gggcccatcg attcgagaaa gagcgtggcc ggtaccgcca
     4921 tgcggcgcgt cacgatcgcg tcggcaatcc gttcgagcag cgcgagatcc tcggtggtga
     4981 aggccggttg gtctgaacgc agggcaaagg cgtgccggag accggctcga agatcgtggg
     5041 tgcgacggga gaacaacccg gatgagaaga cagccataag tgcttgtcag atcagcttaa
     5101 acgattggtt cggcattata tgaaggggca gaaggagagt caatcgagcg atgcatgcgc
     5161 gtcaggttgc tcagcggtgg cgagcgggat acgtaggctc gtgcaacctg tcgtcagcgc
     5221 cgttgctgga ggtattccgc gatgagccgt aagtctccaa cgaaatggcg gtagtcctcc
     5281 tctcgctgcg ctggatccgg accgcggaga atggcggatg gatgggttgt gacgaacacg
     5341 gtctttccca acggcgcggt cagggggcgt ccgcggagtt cattcacgcg cacgcttttg
     5401 ccgaagaccg actgggcggc tgtgacgccc aggcagagga tggcgcgtgg ctccagcacc
     5461 tggatttctg cttccagcca gggccggcag gccgcgactt cggcggcgga gggtttcttg
     5521 tgcttgcggc gtgtgccttg cggctcccat ttgaaatgtt tgacggcgtt ggtgacatag
     5581 acgtcgctgc gggcgatgcc ggcttcctcc agcgccttgt ccagcactct cccggcaggt
     5641 ccgacaaagg ggtggccggc cacatcttcc tgatcgcccg gctgttcacc gatgagcagc
     5701 agtgtcgcgc gagcaggccc ttccccgaag accgtctgcg tggcggtttt atagaggtcg
     5761 cagcccgtgc aggaggcggc ggcgttccgc agcgtcggga gggtcagttt ggaagggaga
     5821 aaggaggcgg ctgatcggag cgatcgtcgc atgattcacc ataccatgcg tcccgagcgc
     5881 cgttccatgc aggctcgcgt accggttcgg cgtcgagcgg ctgcaactcg gtgacggtca
     5941 atgtcaccac gccgaagacg gcttccacca gccctcgcac gagataggcc cgattgggtg
     6001 ccaggaattg atggcagcgg cgatagacgt tcgggaacag cgtggcgtca tagagggcgg
     6061 tggtatcttc gagcgtcaca aattccatcg cctgtccacg gcgcgtctcc accgattttt
     6121 ccgtgaccag ccagcccacc atcgtaatcc gctgcccgac atggcgatgc atgtgcgccg
     6181 ccggcacggg ccgcagccgc tcgattgaat ggcgatagag ggtcaacgga tggcggttcg
     6241 tcaaaaagcc gagcgactcg atctcatggg tcagcttatg ggtgtccgta tagtcctccg
     6301 ggatcgggag cggcccggcg tggcgttgct cctccgcata cagccgccag agcaaggcgg
     6361 gtctcgtcaa ttcgccggcg agggagtcgc agcagccggc tcggatcagc gcgcgcgcct
     6421 gcgtcggggg aaggttgacg cgccgacgga aatcttcgaa cgagcgatag ggcccggctt
     6481 ctgtccggtt ctccacgata cgttcgccga gctctttctg aagcgtcttg acctgcatca
     6541 agccgatccg caaacgatcg ccttcgccgc gataggccca gtcactggcg ttgacgtcgg
     6601 gcggcaggat ggcgagtccc atgcggcgcg cttcggagac gtacgcgaag gccgaataaa
     6661 atccgccctg gttgctgatg acggaggcaa tgaattccgc cggatagtgg gcgcgcagat
     6721 aggcggattt gaacgagacc tgggcatagc tggccgaatg gggtttgcag aaactgtagc
     6781 ctgcgaagct catgatcatc gtccagattt tatcgatggt gtcaggcgcc gctccgttct
     6841 tggcggcgcc gcggcagaac tgctgatagt aatcccgcaa ctgccgcgac ttgtgtttct
     6901 tgctgatgac cttgcgcagc tgatccgcat cttccagggg aaaatcggcg agcgccatgg
     6961 ccaccttcgt gacgtcttcc tgatagacca tgatgccgtg ggtttcttgc agcatgttgt
     7021 ccatcagcgg atgcagcggt tcatacggat ggccatgggc acgccggacg aagtcgtgca
     7081 cgaaagtgat ggccgccggc cgcacgagcg acgacaccat gacgagatat tcaaatacgt
     7141 ccgccacggc gagccggtcc ggcggcatgc cgctccataa ttttctgagc agaaggcggg
     7201 tcgcgggcga ttcgatataa aagcagccga tcgtatcacc gcgccggatc aagtcctgcg
     7261 tcgcatgatc gtgaagcgga tcccagctcg catactcgat cgtgcgaccg gtatggcggg
     7321 caatggcgtc gagcgcatca cgaatgactg cgagcgaccg gttgcccaag aggtcgatct
     7381 tgacgaggcc cgactcctct gcttggtcct tctcccattg aatgaccggc agccccttgg
     7441 cggtgaattc gaccggcacg tagcggcgga tttcatccgg cacgatcacc acccctccgc
     7501 aatgcatgga gaggtgacga aaatggttct gcgcgcgaag cgcctgttcg agaatctcag
     7561 gccacggggc cttcagccgc aaggtccggg agagccggtt gagccattgc tccggggtcg
     7621 gcggagtgga aaagtccagt atcgcttgct ggcgagagac ccgcgcggac atggtgccga
     7681 tttcgtccgc cggcatgcca tagacctttg ccgtttcgcg tatggctgcg cgaaacccca
     7741 gactgttctg attcgccacc atcgccgcct ggcgctcgcc atattgccgg aagacccagt
     7801 tcaggacgcc atcgcgtttg tcccacggaa aatcgatgtc gatgtcgggc ggatccttcc
     7861 gtccgggatt caaaaaccgt tcgaagaaca agtggtgttt gagcggatcc acgtgggtga
     7921 tcttgaggca ataggagacg atcgaggcgg ccaccgagcc gcggccgcag gtcaatggct
     7981 cctgcgtcag aatttctttg acgatcagaa agtaatgcgc gaagcgtttt gcgcggatga
     8041 cggcaagttc cttctcgatg cgcgcgcgga cttcttccga gagcagacca tagcgttcct
     8101 gcgcgccggc ataggtgtcg tctttgagtg tcaggaacgc ggcattgtcg gtgagctcgc
     8161 gaaacgcggg aaagatcgtg tcgccgaaat gccaatcgct gtaacacgcc tcggcgatgc
     8221 gcacgctatt ggccagcgcc tccgggacat ggggaaacgc cgccgccatc cgctccggcg
     8281 gcacaagcca ttgctcagga ttgcagcagg ctgcttgcgg caaccgggag aacgtctgat
     8341 tgagcgcaat tgcgcgcaac aggcggtgag tcgcgaagtc gtcggctcga gcaaaataca
     8401 cgcggttggt cgcgacggac gggacgccga tccggcggct catctcgagg gttttctgca
     8461 tggcgggtcc cggtgtcaat tcgacgtaca ggtcctgtga gtcatccgcc aaccacgctt
     8521 cgagagcggc ctggtcgtcg gtcgcaatga tcaagccgtc gcgatagcgc gccacggctt
     8581 cgatgaaggc gaacgagggc tcgcaatggc gtgcggagag caggcggcac aggttggcat
     8641 agccgccggg agtttttgcc catagcaggg cgcggtgggt gtcggtggtc aattcggcgc
     8701 ccaggatcgg ccgtaggcct tcgtgcctcg cttcttcgat aaatcgaatg gctccataga
     8761 ggccattcgt gtcggtcacg gccagtgcgc cgagtccttg ccgcttcgcc gatcggcaca
     8821 atgtttccag cgacgacacg ccgcgcatgg gtgaataatc cgaatggacg tgcaggtgca
     8881 cgaagggcgt ggtggtcatg gcaacgtctt tccccacgcg atcgcccgtt cgccgaattt
     8941 cgctcgaatg gcatcaagga caagggagat tcgatgggac gccggctgga ccgctatggt
     9001 cgactcgtcg aacagccgca gttgctcggc aagcggttcg agacaatcgg cccgcacgat
     9061 gattcgctgg atcctgaccc gacgccggaa acatcgggcg aagagctgcg cgagcacggg
     9121 ctgaagatcc gcctcccaat aggtgccgta cggcaagatg tgttgagcca tgcgttcggc
     9181 atggtcgctg tggcggagcg ccagcgacag gcgcctgcac atacgccgtt gttgccggag
     9241 cctggcgcag atccgttcga gcagatggga cagtcgtccc agaatgaggt gatcgtcgat
     9301 ttcgtccgga ttgagggtga gagattgttc gatctgcggt tgttcgaccg atggccggac
     9361 gggcgagtgg tcaataccca tggcccagtc atgcagcacg acggccgcgg ttccgagcac
     9421 cgcttccaac tggaccaatg acacgtcggc aatggatccc aaggttctca gattcagatc
     9481 gtccaagcgg cgaaggatgt gcgacgcctg cagtctgttg agtcccggca gcagcgtggc
     9541 aggcaacggc gcgagaaagg cttgctcgga gccggaatag atcgaacgca tctgcggcgg
     9601 cttctccagc gtcgtggccg ccaggtgcga caccagctta ttcatggcca ccccgatttg
     9661 gctgtgccat ccccatttga ccgtcagttc ccgttccagg cgggcggccg tatcgatggg
     9721 acgtccgaag agccgttgtg tgccggtgag gtccagaaat agcgaaccgg gttggattga
     9781 ttcccacaca ggcgcaaagg gcatgatcgc ttgttgcaat tcgcgatgcg ccgcctgcgt
     9841 tctcgacgag tccggcggga tcacacgaag gcccggacat aattgccggg cgagttcgac
     9901 cgacatgccc ggcaggaccc catcgtcaag ggcttcctgt gagacttcac ggaccaggcc
     9961 gcgtggcgta tggaccggcg ccagggcgac cggccggtga cgcaacgacg cctcgtgagt
    10021 ccgcgcgagc acgatctcga acgacggaat ctggagacag acgatgtcgc gatgcatgat
    10081 ggtatctttg tgagtgtaac caatggttac atcgggaagg gggcggtgtc aatggtgcgg
    10141 acgacccatc agcgtctcga acgcagaagc gcgacgaacg tgaacgtggt gtggggaagc
    10201 ttctgagagg ggacgtgaaa gagaatcgtt ctggcggagg ttattctgcc aattgaaggg
    10261 gcctacggtt ttttcgtttc gtcggccgtg ggtgaacaat tcatgccggc gaagggattc
    10321 agcgggttca cgcgcggcga gcagcgttgc gcttccggtg cggccttctc ccctcccgcc
    10381 tgtgagccgg ttggcggttg gagcttatcg atcggatcga gcgggcgcgg attgggttga
    10441 tgaatcggcg agaccggctg agaagggaga aacgtgttgg gctgcaggtc cggcggagct
    10501 gccggcgctt cttcaaccgg tggcgtgaac ccgcctggcg gggacggtga tggcgtcttg
    10561 acgaccgtac agccgcgttt gcctttcggc tggtccgtca gcatggtgcc gccgttcggg
    10621 ccctcgcagc tgtaaatctt tgcttcaacc gggttcgagt gaaggagaac gaggaaggtg
    10681 aagggcagga ggtacagcca gatcatcgtc gatttccccg aatgggatca gaggcggatg
    10741 agggatggcg ttcccgcgga gcgccatgat cccgcacgac tataggcgcg aggccggaac
    10801 ctgtcaatct gcgggagcgg gcttaggggg acatcagccg ggtgaacgtc ccagccattt
    10861 cttcatcagg cccagcaagc cgacctccgg ctccggttgc cgatcgggat attcgatcca
    10921 gagttcctgc gagccgagat aaacgccatc gcgatagctc tgctggctgc gcaattgcgt
    10981 gtaaccctgc tcctgcaata tccggatcat gtgctggagc gcgtcagccg tggtcggcgc
    11041 gtcgggcgtg accacctgcg tggattcgta ccgcaacgtc gcctgatagc cggaggccgt
    11101 ccgcaccaac tccacggggc gattgaaccc tcgctccctg gcgtcgaacc cggcgagttg
    11161 gtgtttctct ccagccgatt ccggcattgg tcttacaagg cgcgatagac ggccagcaga
    11221 tcgctgagtg caatggtctt attcttgagg atcacgcgtt ccgcacccaa cacatccaat
    11281 gcggcgacct tttccgttcc ccccatcaga catttgctcc ctaacgcaag gacgcgttca
    11341 cattcctttt caaccttgcc cttcacgacg ggattcacct tcaggatgtc caccatcttg
    11401 gcgcgagtct cccccaggtg tttttggagt tccgcttcag ggtattcctt ccgcgcggct
    11461 tcatcttcac agcggtcgat gtactgggtc agaaagacat agagccgcac gaaggtttcg
    11521 gcgatctcga tgtgtttcgg ggtcagctga ttgtccgcca ttggatcctc cattcactaa
    11581 ggtgtcgaca tgatcattat gctgtggcga cgtcgcgcgc ggcgcgtccc tgcatcacag
    11641 ccggactttg atatcggtgc cttcgaccgt gacttcatag gccgtcacct tggccgacgg
    11701 gttattgatg caggcacccg tcttcacgtt gaactcccag ttatgccatg ggcaggcgac
    11761 gacatcccct accacatcgc cttcgcccag cgggccgccg cgatgcacgc aggtgttatc
    11821 gatggcataa aaggttccat ccacattgaa gaccgcaatg gcttttccgt tcacctccgc
    11881 gaccatgccg gctcccggct tcacgtcggc ggttcctgcg attctgatca actcgcccat
    11941 acatcctccc tgagtacgtc actcgtccta gtccggcttt cgatccgcag ccggccgttt
    12001 gattttatcc aataaacttt cgatgcgact cttggtcgcc gacacgcccc ctgtttgcaa
    12061 ggctgcggcc agtttggctg cgatgtcgcg aaacgcctgc gcttgcgggg aatcgggctt
    12121 ggcgaccacg atcgggttgc cggtatcgcc tccggcgcga atgacgggat cgatgggaac
    12181 ccgcccaaga aagggaattc ccagcttctc cgccgcccgc tctccgccgc catgggagaa
    12241 aatctccgtc cgctctccgc aatggccgca gacgaaaaag ctcatgttct ccacgatgcc
    12301 gaggagcggc acgttcacct tctgaaacat catcatgcct ttgcgcacgt cgtgcaacgc
    12361 cacttcctgc ggcgtggtca ccgtgacggc gcccgacagc ggcacgagct gcgtcagggt
    12421 gagttgcgcg tctccggttc ccgggggcag gtcgatcaac aaataatcca actcgcccca
    12481 taacacatcg cggaagagtt gctgaatggc cgtgtgcacc atcgggcctc gccacacgac
    12541 ggccgtgtct tccggcacga aaaatcccat cgagatcagc ttgacgccgt ggctttccgc
    12601 cggcgcaatc ttgccgtctt tctgctcagg agtcttctcg acccccatca tcatcgggat
    12661 gttgggcccg tagatatcgg catccagcaa tccgaccttg gcgccggtga gcgcaagagc
    12721 gaccgcgaga ttgacggaga ccgtggattt accgacgccg cccttgccgc tgctgacggc
    12781 gacgacatgt ttgactccgg gaataatatt gggtcgggcg gccgcttcgt cttgatgcgg
    12841 tgcgccgcct ggttcttctg ccatagtgat gcctcctcca ccccgttggt ccgatcggat
    12901 tacgtgggtt tctcgcatat taagctatcg ccgcggcgaa aagaaatggg tcagtcggcg
    12961 cagcaggcgg ttgggtcgaa gagatcagcg atgtaagagg aataagttga gaggatggtc
    13021 aaaaaactct acccggtgcg gtcgcagcga gcgaagagcc gcggggtatt cgcagaaata
    13081 cgtcgagggg cggagcgatg cgagaacaac agcggcgggc gttgttcacc agccgtttac
    13141 gtgcgttccc gatggaggtt atacgtcagc cctaccagcg agagcgtata gatcaaccat
    13201 ttggacggat cgaaattgta ccatttcgat ccgttccgat agtcgtgcga ataggtatgg
    13261 tgataattgt ggtagccctc gccgaagctg atgaacgaaa tcagccagct gtcccggctg
    13321 ctgtcctgcg tgccgtgcgg ttgagtgccg accatgtggc acagggagtt gatggtgaag
    13381 gtggaattca acaccaagac ggtgcgcaac acgccggcga gtaagaaaca gccgagcccg
    13441 ctcatcagtc cgccgttcag atacccggcc gcgaagggca gcaacagtcc tgaggcgacg
    13501 atcacccagt agtaccggtg ttgccagaga atcatcgggt cggtacgtaa tttcgcggca
    13561 aaccggtctt cacgatatgg tgtattgatg aacagccagc ccacgtggct gtgccagaat
    13621 cctttgctcg cattgtacgg atcggcttct tcatccgtat gggcatggtg acggatatgg
    13681 tcagcgcacc agagaagagc ggaattctgt acggcccatc cccccatgat caacaggcag
    13741 atcttgaccc agagatggct ctcaaagctg cgatgagtga tcatccgatg gtagcccacc
    13801 gtgatcccca tgccggtgac gacatagagt atggcgagca acgtccaatc caggacggtg
    13861 tagtcatagt aataagcgaa gaggggaacc ccgacgaagg tcaggatcgt gagcgcagtg
    13921 aagagggcga cggtgcccca gcagacggat tgtgtggatg agtcggccat cgtactcctt
    13981 cggaacctgt gcgcaactca tcgccacagt gcaccgccat acttagagaa tgggtgaagg
    14041 caaacggcgc actgtaacgg agccgccgtc agattttcaa ggggagaaac gcggttggct
    14101 gccgcacgcc aggtgggcgt gaaggtcacc tgacctactc agtctgtgct accagcgcat
    14161 aaagggcgcg ggattgaaag gatgcctcga cacccaggct ctgcctgtct tgaggaggaa
    14221 tgtgtgaaag ccgtgattgg gaaagtggtt cttcacgtct gtgatgtacg atcgcggaat
    14281 cccgcaactc aataggccca acgaaacatc aaccaggtcg ccttttcgaa acacttcgac
    14341 aagagggtaa cggcgatctg gataggcgcg taccttgtga tgcatgccga tcatcagggc
    14401 catttcttca gaccactctt cccgccctga atcggacagg tattgggcgg cgtgggaaat
    14461 tgaggccggg aggtaatcga gcgtgcgatc aggccaaaga cccatatcgt gaaagcaggc
    14521 ggcgatggct aactttgtgt tctcctcctc ggtgcatgga tgtaacgcca ggcagaagtt
    14581 gaacatgcgg tacacatgtc ccttgtatcc caggtagtcc tccccgatcg ccccttccca
    14641 tttcgcaaga attatttcga tcagctcgtg cgtggtctcg atcggcatag gaggcatctg
    14701 gcaaatcacc ttggatgtgg agtgcatggc acgtggtcct ttctgttcga ctggaggatg
    14761 gcaggtgagc gaggatctat cacgcaggag tcggcggccc tggcacaagc cgcgtgccga
    14821 cctgtggcga tgggcaggcg gtcgtgcggt cggagccgga ttctaacaag acacggagaa
    14881 tttgcaagac tcctcgcgcc gatccagcct ggctcgcgct cttgttcgac agcacccctc
    14941 ccagtgctgc acgttcggag gcggctgtac aatcacttat aatcctgcgc acggagcggc
    15001 tgtcagctgt tcacgtacag gcgcatgaac agaaatgacg acgcgaggcg gcctccggcc
    15061 gattgacccg tgcccgcaat gcgcctagag tggcgtgtac gtgtcaccct ctatgtccgc
    15121 tggagaccct tccgatgctt ggaacagtca cccgtaaagt cctcaagaca atcctgtcgg
    15181 atactgcgcg gcagcgcatc ttgacggtgg agcgtgtcca ccgggagggc ggtctttttg
    15241 acgccgattc gatcttttac cgctgcgtcg gaaccgtggt gacctgggga accggttccc
    15301 gcgtacactc ggggccgttt gcaggcatgc gatacatcca acatgcactc ggagttcaca
    15361 gcagcgccta ctgtcccaaa ctgctcggga cctatgaaca ggaactccat ccgctcgtcg
    15421 aggctctgcg aaccggacac ccctacgctc acgtgatcaa catcggtgcc ggtgaagggt
    15481 actatgcgat cggtttcgct cgttgcctgc ctcagagccg ggtgacggcc tatgaagctg
    15541 atgctgagag tcgggtcatc ttggggcgaa tggcggagat caacggggtg gctccgcgtc
    15601 tgacgatccg ggagtcttgc accccgtctg ggttgcaggc ggcaatggcg cagccgggaa
    15661 aaaccttgat cgtctgtgat gtcgaaggcg ccgaacaaga gctccttgat ccggtcgcca
    15721 ttcctgccct cactcgtgcg gatatcctgg tcgaactcca cgactttctc attcccggca
    15781 tttcaggcgt aatccgaaag cggtttgaaa atacgcacca gattacggag attccagccc
    15841 ttcctcgaca gctggccgat tggccactct cattaagcct cccgaaggtc tatcggcgaa
    15901 ccgccctctc ggaatatcga ccgggaggga tgtgttggtt ctggatgaag gcccgcgggt
    15961 aacgcagttc tcgccgtcgc gcatgcagat tgagccaggg gttgcccggc attctccatg
    16021 gcgttcctct ttgtggtctt gtccgcctcg gggatgattc tcgctcgaac gcgcagccaa
    16081 attctcaagt gcagaggcgc ggtgtatact gcaggaaaga gctcttcacg tcgtcctgga
    16141 ggaccacatg actctggacc ctgccctgct tgaaccccgt attcgtacca tcggtgaaga
    16201 tctcgcccgc cgttccagcg gattgtcgcc cggcctgttt gattcccgtt ggtggtcgc
//
LOCUS       DAOQPD010000091        15879 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1863_length_15879_cov_14.185857, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000091 DAOQPD010000000
VERSION     DAOQPD010000091.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 15879)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 15879)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15879
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1863_length_15879_cov_14.185857"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..686
                     /locus_tag="PK063_16145"
     CDS             <1..686
                     /locus_tag="PK063_16145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HMZ98633.1"
                     /translation="FNLAMREWEWCRENPMHRVSMEQVRNEVDRWLTPEEEDRLMAAS
                     SPWLREIMVFALNTGMRQGEILNLQWQDVDFSRGTLIVMQSKNGTRRTIPLNTKVYEL
                     LAAKQAATGLSRGPVFKTPLGNLLQVRFLVREFCEARNRAGIPDFRFHDMRHTFATRL
                     VQRGVDLYKVQRLLGHKTNLMTQRYAHHSPESLREGVKVLDECQPERFSTNLAHGPVF
                     EDFRGSTAS"
     gene            2307..8012
                     /locus_tag="PK063_16150"
     CDS             2307..8012
                     /locus_tag="PK063_16150"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98634.1"
                     /translation="MTFHGRIESADGGVPKNGWDAYRLVFTSSAAVDGVPRSLDRSIT
                     IRGDGSYSADPGDPIPADASLSVVSPEGQILARRQFSSLVEDGTPYLKPFPVRPRDLD
                     LVIDPVDEPVDQRTRVSGRVFVAAGASSDHSAAAELAVRIFGASGDGARFAPIFTGVT
                     DRSGYFAGFVQRQRLTAAFGETGGGAALVRHTIHITPGNWLPEPVLLFIDAPGKTSDE
                     ENCGCTAPPPPTPGSAELAVHGEAFSTDLGAGCQDFTVPNRTLEEFDFFKIVRTTDPA
                     IRGLTLPDTVRNEIDLPQIASLAFDRGTLAQAVGASAIAVQTAPKPPTPELPVSSDLR
                     RNATPSVEGARTMARLATVVANTEAAAAATMADTGIADYVDVSPLQSSGVRRAAEWGN
                     SVDERAMQAALREAVAKIPPAAIKAALEDPDGFTPEGLMTLQRSVSAKALRDYLNWRI
                     KPVANRGELNEINLVDWDFTPEFYQATSIAHGHILHFKQEWRADGYSLGELVRSIPLA
                     PGQKKQIAVLEWDRADTAARTEATDVSEAVSATLSRDRDIDEIANVAFSESLRGGSRA
                     TTSAGGGGFGLAIGPLVIGGGGGAAKASSNAWSDNSRSLSGQTLNQLRDRVSQGASAV
                     RNQRSTVVETVGQSERVTATTEVIANYNRCHALTIQYFEVLRHFAVHETLASVQECLF
                     VPLEMTTFDDAKVLRWHDMLLNACRDRRLTPGFEAIRRLNSTEPLPPNRRYADDPIEE
                     MTGNLRVRISIARPKDPKDATVAVQDTEWRFFGFVLRVNPEVLYEVYRRDQVKRDKIF
                     RTEIAPQIAQAFLESLRVMLVDRDGREHDAGFDITVASRYAENGVMEVELNNTGRGPR
                     LTRAQIAGVSIQTDFELPEFSKVIVESASASYATERFSGSLFTGSVNDDVVKGDPAFL
                     SASQLSRAEERNQLAEMRRLRRRLLRHLNDNIEYYHRAIWLGMDANRRYMLLDGFEAP
                     RSDGRSVASVVENRLVGIVGNCLVMPVAPGFQLDPVLAEALAEEEDPQKALERLYKVE
                     AAPPRRLSVPTKGVFAEAMPGKCNSCEIIEEDRFWRWKDFPLPDSPSAISALSTASRF
                     AAPGSLRPTALPDAIVKFQALPSLPDPTGMAAALSLLGQDVFKDLTGLTNNQKNAMAA
                     LTTAMGTSEAFAGEAFKLAMAKDAARNLDRTLEQIKAAKKADLLTAEEASKATRDAIL
                     RSIAETPASSKDVVTTPEVEEAIKKAAETPGGSAKITREKGEKTEEVSFAVDESGLQI
                     GSATGHVREYPVEIWVEVPLVHDVVDDTTLDYSDSDRVDTLEPARQKEAVPAKLAGTD
                     ILVDRIGSAIDSDLMREGPSGRLQIRVNAMIGYPADPADNKKILQPQGKTKYGFVAMI
                     HGNSTAWKLEDGPVTDAPPITGSSLDVKTVPVTERGDYRGYTYLQKHLAELPRPIVSI
                     SFSHGLPNMLDHFVETRSRMLLAAIGQVVADAAQPGSLLGDTVDFDATGLMGHSRGGE
                     AVVRAFEQSKGMAGFTVTAICSLAPTDFLGASNNFKLSLPPREGVNYLVFYGGLDGDV
                     VGWRETTTADRGGNGFRLYDRTECDKAMVFIPRATHDRFNTVWAANEEVEWPTSKHGV
                     TLPGVPDRTLSKSTHEALAKEFIGGFFDLILNGNSGEQARFRNEVKSPTGAAISHQWQ
                     FATASQPLDTFTGTAPDFGTRTLPAGATIERFAPLTPVASRDEKIPHDDNACILATSS
                     AGTPAIVHEFTGGPPSSFDTIRFRLGRLYPSLQKSDVDTAVTLSPASVDVAKLRALLK
                     TKQEDEINLVKPPEFDVILEDTDNKTARIAHASLLLGQQNGWARPEAKVPVEVVKLPS
                     GDIFAVAKDCTLMSLQTLQIKTVQLVGIDPSKLRKISFEFKTPATAQEVWLDSIDFVL
                     T"
     gene            8022..8312
                     /locus_tag="PK063_16155"
     CDS             8022..8312
                     /locus_tag="PK063_16155"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98635.1"
                     /translation="MNFKSLTVLAVPEEVQTTTGFVARVFAEIESVPATGLPLTAEIG
                     GQRMEALGVVQGLEPLLSGFVRVVPQPGDELVIKIGEVTIPTGLTVSDPAIA"
     gene            8327..12574
                     /locus_tag="PK063_16160"
     CDS             8327..12574
                     /locus_tag="PK063_16160"
                     /inference="COORDINATES: protein motif:HMM:NF023802.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="papain-like cysteine protease family protein"
                     /protein_id="HMZ98636.1"
                     /translation="MKLNGQLTGARSGYAGHQVEIFIPALISAETGARILAPTFVRVP
                     VSDDGKFSFDVKSGLTLSSPMEVAVRAPSGERLAFLPQPTLSDFTIKVLPHTAVPVAP
                     ETSPTDPALGPLKTRINLHDKAEQDRAANQLVSVWGIHPVAGGTEPVQNVLGASYADP
                     RGVAVVEIPRAAWRSLEIEVPGHRGPNKRFALKQTPDGLPVESTDILVDLTPLPSSTE
                     EAQCDCKESTLPRTPGHEELVGSGVFAADPVAGGCVNLAVPNRTIEEYNFQSLVRTTD
                     PFLFTSKPPRPRPLPPLSPTALTLAAELAYGVNALDTQLGQAAAGVTGTQPSTRGTAV
                     LRNGEAALDALRLESHTYRSTGLAAVRAWRETAAKDRVVNAIMERASSLSEDTLRHAL
                     ADPDGFTPVALMTAERHRAFEQLGQASETTPASGRTPIAAGNMPQWDAQPKTYQAATI
                     AHGHLLEWRQVWRADGYSLGDLLYSLPLAPGQKRQIVVVDWDRRETGMRTESRTVAES
                     FSADLSRDRDVAEIVNSTITESIRAGSSTRTWGGGGGLGLGIPFSGGFFGLGVAGGGG
                     GSDSQAWQNSARSLSASAGQDISDRTQQAATAVRSQRATVVTGRQQHESVSVTAEVVA
                     NYNHCHSMTVEYFEVLKHYRVDLELASAQQCLFIPLQMTRFDEMKSLRWRDVLSQHLR
                     DRTLAGGFDAIERILTGYVDSDFPPARYADEAMTELWGELRVELDIRRPREPRENEDI
                     NDYLNNNWNTWNILFGPGAAARAYDQSVRERALADKIFADELAPRIARAFADTLQFEL
                     CVDVNGTPVYVPVTADFTMVSDYRAGREHLIAFRCVLPSNQQVARARIKAVRFSTTLG
                     EITPGSRSILRYVHVSYRNRYRSFALLSPRRVRDEIKAGDAVFLATYALAKWEELNPR
                     LEDLRLRDRLLKHLNEHVEHYHHVIWWLMDPGRRFMLLDGFIAPDSEGRSVASVTENR
                     LISIIGNSLVLPVAPGYVLDPVVKNAEDPDRPIDLLEAYRPAIPFAPKRISVPTRGVH
                     AEAILGECNSCAILDNKRFWDWASEPIEEEPTPIQETSTETRRQTPPDTEPTPFTAPI
                     VGIQNVPEAPAPTALTDFTKLLGQKDLFKDVTGLELNQANALGAFQRAMQTANFFGKM
                     AAAGAKASFANRQSENVMKKVTEAVKNGDMSKEDAKTVIDKLIGSMNGTGGESDKPLT
                     GEKAVKDALNKVVSGSGKVNVSSESGDGKQTVEAKFADKNGSAQSTDVQIDGVPAVDQ
                     VKSQGCWAAALTMLISFQRKATMPIETVLAEGGPEYVEKYQSNGGIKPSEIAALKDTF
                     KLRDASSGAITLASLSSRLSERGPLWIAVDDDPSQQFSAHARVITGLKGNMVRFIDPD
                     GGVEGEEEFVVLVRQLNELSKGVRSAFGGYAPLILSL"
     gene            complement(12587..13009)
                     /locus_tag="PK063_16165"
                     /pseudo
     CDS             complement(12587..13009)
                     /locus_tag="PK063_16165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611376.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            13181..13636
                     /locus_tag="PK063_16170"
     CDS             13181..13636
                     /locus_tag="PK063_16170"
                     /inference="COORDINATES: protein motif:HMM:NF039390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98637.1"
                     /translation="MIIEHLTYNPLEETHTIDIFAQQKKEDLSKGFKANRHIYDYVLT
                     DSSNERTFVGELDASSEVVVYAKLPKAFHIPTPVGNYNPDWAIAFEAGQVKHVYFVAE
                     TKGSMSSMDLRKIEETKIECARKFFAKITSDQAKYDVVNSYGKLMELVK"
     gene            13792..14187
                     /locus_tag="PK063_16175"
     CDS             13792..14187
                     /locus_tag="PK063_16175"
                     /inference="COORDINATES: protein motif:HMM:NF025713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HMZ98638.1"
                     /translation="MEQCVQSDPAHAIGTAKELIETCCKTILAQRGKSLPGKPDIPEL
                     TKATLKELKLVPDDVEDSARGSDIIKRLLQNLGTIGNNLAELRGLYGTGHGKHAHTGT
                     LTPRHARLAVGAASTLATFLFDTHRERAS"
     gene            complement(14361..15101)
                     /locus_tag="PK063_16180"
     CDS             complement(14361..15101)
                     /locus_tag="PK063_16180"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98639.1"
                     /translation="MEQSAARRGPIFAEGASGRSRPRSLIAAISEIQELAVVEKLGTP
                     LPEHLILLDRSFAYTEVGVHSVVVDGLINMLGVPMGLGVLGSLMPIFGDPDPSLFDQV
                     FAQLIGVTYGVGYAVMIGHNLGSCYIGKVCKRAIQDIYQSMIVANIIKVILLSVFFNF
                     MYQLLTPEHVQEGVKLLWPILRGVMSDQMVVGVQDWVISMREVMIPSATMVILVTIAT
                     LCVPYVYFVIGGREAAEEKRRNRLYDVC"
     gene            complement(15104..15322)
                     /locus_tag="PK063_16185"
     CDS             complement(15104..15322)
                     /locus_tag="PK063_16185"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98640.1"
                     /translation="MDPETFIAVSSWVNTTLLAGVPLRILASATLAATFWFGAYKQRI
                     ALGFLFFMLTILLAYFRPLINLIGSGSM"
     gene            complement(15335..>15879)
                     /locus_tag="PK063_16190"
     CDS             complement(15335..>15879)
                     /locus_tag="PK063_16190"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98641.1"
                     /translation="RIGKDRLGVILRQADGQARVKEMILSTQEMQEKPLDSWCAGSEV
                     LAIVAPRINRPLKGNKWAAFSLKGVVYVTPDALLEAAKELARQKKIVEMGLIRSTDRE
                     DTLRRLVKILGAADLLAMEIGEHFYGRPFDIFTKKAGIKQRGYFVPVKLEAFRIAESE
                     LESRKVAFMQLVTEFQLGRG"
BASE COUNT         3452 a         4860 c         4481 g         3086 t
ORIGIN      
        1 ccttcaacct ggccatgcgg gaatgggaat ggtgccggga aaacccgatg caccgagtct
       61 ccatggaaca ggtgaggaac gaagtggacc gttggctgac gccggaggaa gaagaccggc
      121 tgatggccgc gtcgtcaccg tggctgcgag agattatggt ctttgccctg aataccggca
      181 tgcgccaagg agagatcctg aacctgcaat ggcaggacgt ggatttctca cggggaacct
      241 tgatcgtgat gcaaagcaag aacggcacac gacgaaccat tcctctcaat accaaggtct
      301 atgaactcct ggctgcgaaa caggctgcaa ccggcctgtc acgtgggcca gtcttcaaga
      361 ctccgctcgg caatctcctg caagtacgtt ttctcgtgcg ggagttttgt gaggcgcgta
      421 atcgggccgg aattccagac ttccggtttc acgacatgcg acacaccttc gccacgcggt
      481 tggttcagcg cggggtagat ctctacaagg ttcaacggct gctcgggcat aagacgaatt
      541 tgatgacgca acgctatgcg catcattcgc cggaaagcct gagagagggt gtgaaggtgc
      601 tggatgagtg ccaaccggag cggtttagca caaatttagc acacgggccg gtttttgagg
      661 attttcgagg ctcgacagcc tcgtaagtgc ttgatttatt gtggtgagtc ggctgggatt
      721 cgaacccagg accctcgcct taaaagatcg aaagaacggt ttttgacaag tgctcgctat
      781 tgcaacggtt tccccaattt actcagtata tcgatcactt aggagcttct attgattcta
      841 tgcgttccgc tccttatcca tcaattctgc attgttttgt cacaaatttg tcacagcaag
      901 tccgtacact acccggatca gacagtcatg tctacgatgc aataggcagc ctctatccaa
      961 ccactattga tgacccatat gcattccgat gcggggatac gtcgaggcct gctgacaacc
     1021 gacctgcggt tttcgaattg aaccggactc atcgccacat caacaatttc aacaagatag
     1081 ctcggcaaat cacggcaaaa ccgggcaaac aatccgcaaa tctgcaaccg gttgcaacca
     1141 ggaatcgggc cctcaagact cgtctccaga taagggagat gagtcttgag cattcgtctt
     1201 acccttccgt gtcgtcgtcg cttgttcgct ggtctgatag cctcgtttgg cgcctgggcc
     1261 ggtcactgct cattagggtc atagtcctct ttcggatata gtcacgaagg tgggcttgtg
     1321 ccttcccatc ccatgaccag cgtttcaatc ccgaactcat cgcctctcac ccatcacaca
     1381 atccccgctg ccaccgagat ctgtttgcgc gtcggcagtc tcactctgag cgagcacaca
     1441 ccgccgagct ggagcggcaa ggtgccggaa agtcgccaac cggcaagtgg ctttcgacac
     1501 gtgcgattca tcggatcatc acggaaggcc tgttgttagc tggagtgaaa aagccgggca
     1561 tcgtggtcca tagtctgcgt cctcgtccca accgttgcac ttggaacttg aaaccgccat
     1621 gctaatctaa tgcaggtcca gaagatgatg cgccatcagc actatgcgac caccgagatc
     1681 catgtcgagg acgtgcagaa gctactggag ggggcagaag aggcggccac gcagatctaa
     1741 ctccgcaaga ttttgaatcg gctgcgagag atatgagaga acaaggcagc aggactcaga
     1801 catacacaag ccgcaactat ttctcttcgt gagtgctcat cccagtcttc cctctgagcc
     1861 gcatcggaca gagaagactg tttcacattg cgacatattc tcttcctacc caacgtatct
     1921 ttttcgattc agtgtgaatc aaattggata cggttggaac ctctgctggg tcagtgcacc
     1981 agacatcacg ctgaaattat tccgaatggt tcatgaatgc tgcagaaaaa tactgtgcat
     2041 caaacttgct ttccgatctg gtaggcctga cggcaaatta ttatgcttga ctgaatcacg
     2101 gatacccata agcataagcc tcatgatcat ccgggacttg acaactatat cgagatattt
     2161 tgtcgatttc gactacatca gccccaatga cttcgaacga ttggcgaaag tggcataact
     2221 gagtggctgt ttctatttga ccacaacacg attttcagcg tacgcaagtc gacttagctg
     2281 cagtaagaga atttgaggga tgcaacatga ctttccacgg cagaattgag tcggccgatg
     2341 gaggtgtccc caagaacggc tgggatgcgt atcggctcgt tttcacgtct tccgcggcag
     2401 tcgacggtgt accgaggtct ctcgatcgct cgatcacaat tcgcggtgac ggcagttatt
     2461 ctgccgatcc tggtgacccc atccccgcgg atgcatccct ctccgtcgta tctcccgagg
     2521 ggcaaatact ggcgcgccga caattctcat cgctggttga agatggcacc ccttatctca
     2581 aacccttccc ggtacgtccc cgcgacctgg acctcgtcat cgatcccgtt gacgagccgg
     2641 tggatcagcg gacccgtgtc tccggccggg tctttgttgc cgcaggcgca tccagcgatc
     2701 actccgccgc ggcggaactc gcggtcagga ttttcggtgc ctcgggcgac ggcgcccgct
     2761 tcgcccccat ttttacaggc gtcactgatc ggagcggata cttcgccggt ttcgtgcaac
     2821 ggcagcgcct cacggccgca ttcggcgaaa ccggaggggg cgccgctctt gtccgccaca
     2881 cgatccacat cacgcctggg aactggctcc cggagcccgt gctcttgttt atcgatgcgc
     2941 ctgggaagac cagcgatgaa gagaactgcg gatgcacggc gcctccgcct ccaactccgg
     3001 gttctgcgga gctcgcggtg cacggtgaag cattctcgac cgatctcggc gcgggctgtc
     3061 aggattttac ggttcctaac cgcacgctgg aagagttcga cttctttaag atcgttcgca
     3121 cgacggatcc ggctatcagg ggcctcaccc ttcccgatac cgtgcgcaat gagatcgatc
     3181 ttccgcagat agcctcgctg gcattcgatc gcggtacact ggcgcaggca gtcggagcgt
     3241 cggccatcgc ggtgcagacc gccccaaagc cgcccacccc ggagctaccg gtatcatctg
     3301 acctccgtcg aaacgcgact ccatccgtcg agggagcccg cacgatggct cgccttgcaa
     3361 cagtcgtcgc gaacaccgaa gcggcggcag ctgcgacgat ggccgacacc ggtatcgccg
     3421 attacgtcga cgtcagcccg cttcagtcgt caggcgtgcg ccgagccgcc gagtggggca
     3481 attccgtcga cgaaagggcg atgcaggccg ccttacgtga agcggtggca aagatcccgc
     3541 cggcggcaat aaaggctgca ctcgaggacc ctgatggctt caccccagaa gggttgatga
     3601 cgctgcagcg cagtgtctcc gccaaagctc tgagagatta cctgaactgg cgcatcaagc
     3661 cggtggcaaa ccgaggcgag ctgaacgaga tcaatctcgt cgactgggac ttcacgcccg
     3721 agttctatca ggcaacttcc atcgcccatg gacacattct ccatttcaaa caagaatggc
     3781 gcgccgacgg ctactcactc ggcgagttag tgcgtagcat tccgctcgct ccaggtcaga
     3841 agaaacagat cgcggtgctc gagtgggatc gcgcggatac cgcggcgcgc accgaagcca
     3901 ctgacgtctc cgaagccgtc agtgcaactc ttagccgcga ccgcgacatc gacgagatcg
     3961 ccaacgttgc cttcagcgaa tcgctacgcg gcggctcccg cgcgaccacg tctgccggcg
     4021 gtggcggatt cggcctggcg attggacctc tcgtgatcgg cggaggagga ggggccgcca
     4081 aagccagttc caatgcctgg agcgacaact cgcggagcct ttccggccag acgctgaacc
     4141 agcttcggga tcgcgtttca cagggcgcct ctgcggttcg caatcagcgt tctaccgtgg
     4201 ttgaaaccgt cggccaaagc gagcgtgtga ccgccacgac ggaagtgatt gcaaactaca
     4261 atcgctgcca cgctctgacc atccagtact ttgaggtgct tcgtcatttc gcggtgcacg
     4321 aaacactggc cagcgtccag gaatgcctgt tcgtaccgct ggaaatgacc accttcgatg
     4381 acgccaaagt gcttcgctgg catgacatgc tcttgaatgc ctgccgtgat cgtcgtctga
     4441 ccccgggctt cgaagccatt cgccgcttga attccaccga gccgctgccg cccaatcgcc
     4501 gttacgccga cgacccgatc gaagagatga ccggcaacct gcgagtgcgc atctcgatcg
     4561 cgcgtcccaa ggatccgaag gacgcgaccg ttgccgtgca ggatacggag tggcgcttct
     4621 tcggtttcgt gctccgtgtc aaccctgagg ttctgtacga agtctaccgg cgcgatcagg
     4681 tcaaacgcga caagatcttc cgcaccgaga tcgctccgca gatcgcccag gcatttctgg
     4741 agagcctgcg cgtcatgctt gtcgaccgtg atggccgcga gcacgacgcc ggtttcgaca
     4801 tcacggtcgc atcccgctac gccgagaacg gtgtgatgga ggtcgagctc aacaacaccg
     4861 gccgcggacc acggctgacg cgcgcgcaga ttgcgggtgt ctccatccag accgacttcg
     4921 aactgccgga gttttcgaag gtcatcgtcg aatcggcttc agcctcttat gccacggagc
     4981 gcttcagtgg ctctctgttt accggatccg tcaacgacga tgtcgtgaag ggcgatccgg
     5041 cattcctctc tgcgagccag ctaagccgcg ccgaagaaag aaatcagctc gcagagatgc
     5101 gccgcctgcg ccgccgtctc ctgcgccacc tcaatgacaa catcgagtac taccatcgcg
     5161 cgatctggtt gggcatggat gcgaatcgcc gctacatgct gctcgacggc tttgaagcac
     5221 cccgatcgga cggtcgctcc gtcgcctcgg tcgtcgagaa tcgtctggta gggatcgtag
     5281 gcaactgcct cgtcatgccg gtggctcccg gattccagct cgatcccgta ctggccgaag
     5341 cgctcgccga agaagaggat ccgcaaaagg ccctcgagcg tctctacaag gtcgaggcgg
     5401 cgccgccgcg ccgcctcagc gtcccgacga aaggagtatt cgctgaggct atgcccggca
     5461 agtgcaacag ctgcgagatc atcgaagagg atcgcttctg gcgctggaag gattttccgc
     5521 tgccggattc gccctccgcg atcagcgctc tgtccacggc cagccgcttt gctgcgccgg
     5581 gaagcctccg tcccaccgct cttccggacg ccatcgtcaa gttccaggct ctgccctcct
     5641 tgcccgaccc caccggcatg gcggccgcac tcagcctgct gggtcaggac gtgttcaaag
     5701 acctcaccgg cttgacgaac aaccagaaga acgccatggc agcgctgacc accgcgatgg
     5761 gaaccagcga ggcgttcgcg ggcgaagcgt tcaaactcgc catggccaaa gatgccgcgc
     5821 gcaatctcga tcgcacgctg gagcagatca aggccgccaa gaaggcagac ttgctgaccg
     5881 cggaggaagc gagcaaggcc acgcgcgacg ccatcttgcg gtcgattgcg gagacaccgg
     5941 catcatccaa agacgttgtg accactccgg aagtggaaga ggctatcaaa aaggccgcgg
     6001 agacgccagg cggctcggcg aagatcacac gcgaaaaagg agaaaagacc gaagaggttt
     6061 cattcgccgt cgatgaatcg gggctgcaga tcggcagcgc caccggtcac gtgcgggaat
     6121 acccggtgga aatctgggtc gaagtgccgc tggtccacga tgtcgtagat gacaccactt
     6181 tggactattc cgattccgac cgagtggaca cccttgagcc ggcgcgacag aaagaagccg
     6241 ttcccgctaa actcgccgga accgacattc tcgtcgaccg gatcggcagc gccatcgata
     6301 gcgacttgat gcgagaaggt ccgagcggca ggctgcagat ccgggtcaac gccatgatcg
     6361 gatatccggc cgacccggcg gacaacaaga agatccttca gccgcaaggc aaaacgaagt
     6421 atggtttcgt cgcaatgatc cacggcaact ccaccgcgtg gaagctcgaa gatggcccgg
     6481 tgaccgatgc gccgccgatc accggcagct cgctggacgt gaaaaccgtc cccgtcacag
     6541 agaggggaga ttaccgggga tacacgtatc ttcagaagca cctcgccgag ctgccgcgtc
     6601 cgatcgtttc gatcagcttc tcccatggat taccgaacat gctcgaccac ttcgtggaga
     6661 cgcgatcccg aatgctgtta gccgccatcg gtcaggtcgt cgcggacgcc gcacagccgg
     6721 ggtcgcttct tggcgacacc gtggatttcg atgccaccgg gctgatgggg cattcccgcg
     6781 gcggcgaggc tgtcgtgcga gcgttcgagc agtcaaaggg catggcaggt ttcacggtca
     6841 ccgcgatctg ctcgcttgcc cccacggatt tcctcggtgc cagcaacaac ttcaagcttt
     6901 cgctgccgcc ccgggaaggc gtcaattacc tcgtcttcta tggcggattg gacggcgacg
     6961 tcgtggggtg gcgggaaacg acgaccgcgg atcgtggcgg aaatggcttc cgtctctacg
     7021 accgcaccga gtgcgataaa gcgatggtct tcatcccacg cgccacacac gaccgtttca
     7081 acacagtgtg ggccgccaac gaagaggtag agtggccgac ctcgaaacac ggcgtcactc
     7141 tgccgggcgt gcctgatcgg actttgagca aatccaccca tgaggcactc gctaaagaat
     7201 tcattggcgg cttcttcgac ttgatcttga atggcaattc aggcgagcag gcgcgcttcc
     7261 ggaacgaagt gaagagtccc accggcgccg ctatttccca tcaatggcag tttgctacgg
     7321 caagccagcc actcgacacc ttcactggga cggcgcctga tttcggcacc cgaacgcttc
     7381 cagccggcgc caccattgag cgcttcgctc cactgacgcc agttgccagc cgcgatgaga
     7441 agatcccgca cgacgacaac gcctgcattc tggccacttc ttcagcgggc acgccggcga
     7501 ttgtgcacga gttcacaggg ggtccaccaa gcagcttcga taccatacgc ttccgcctcg
     7561 ggcgtctcta tccatcattg cagaaaagcg acgtcgacac cgcagttaca ctcagcccgg
     7621 caagcgtcga tgttgcgaag ttacgagcgc tcctgaaaac aaaacaggag gatgagatca
     7681 acctggtgaa gccgcctgag ttcgacgtca ttctcgaaga caccgataat aagacggctc
     7741 gcattgcgca tgcctccctc ctgttgggtc aacagaacgg ctgggcacgg ccggaagcca
     7801 aagttccggt cgaggtcgta aagttgccaa gcggtgacat cttcgctgtc gccaaggatt
     7861 gcacgctgat gtcgctgcag actctgcaaa tcaaaaccgt gcagctggtc ggtatcgatc
     7921 cctcgaagct tcgaaagatc agctttgagt ttaaaacgcc ggctacggcc caggaagtct
     7981 ggctggacag tatcgacttc gtccttacgt aggagcaagc catgaacttc aagagtctca
     8041 cggtgcttgc agtccctgag gaagtacaga cgaccaccgg ctttgtggcg cgcgtcttcg
     8101 ccgaaataga gagtgtcccc gcgaccgggc ttcccttgac cgcggaaatt ggcggtcaaa
     8161 ggatggaagc gctcggggtc gtgcagggac tcgaacctct gctcagcggc tttgtcagag
     8221 tcgtgccgca gcccggtgac gagctggtca tcaaaatcgg ggaggtcacc atccccaccg
     8281 gcctgacagt cagcgatccg gcaatcgcgt gaggagaaag aaggcaatga agctcaatgg
     8341 acagctcacc ggcgcacgtt cgggctatgc gggacatcag gtcgaaatct ttatccccgc
     8401 ccttatctct gccgagaccg gagctcgcat cctggcacca acgttcgtgc gcgtgccggt
     8461 atcggatgat ggcaagttca gcttcgatgt caaatccggc ctcacgctca gcagcccgat
     8521 ggaggtcgcg gttcgcgctc cctccggcga gcgcctcgcc ttcctgccgc agccaacgct
     8581 ttccgacttc accatcaagg tacttccgca taccgcagtg ccggtggcac cggaaacgtc
     8641 ccccaccgat cctgcgcttg gacctctcaa gacgcgcatc aacctccatg acaaggcgga
     8701 acaggatcgc gccgcaaacc agttggtgtc ggtctggggc attcaccccg tcgccggagg
     8761 aaccgagccc gttcagaatg tgctgggcgc ctcgtatgcc gacccccgag gggttgcagt
     8821 tgtcgagatc ccgcgcgcgg cgtggcggtc cctggaaatc gaggtgccgg gacatcgcgg
     8881 gccgaacaag cgattcgcgc tgaagcagac ccccgatgga ctgcccgtcg aatccaccga
     8941 tatcctggtt gaccttacgc cacttccgtc gtcgactgaa gaagcccagt gcgactgcaa
     9001 agaatcaacg ctgccgagaa cgcctggtca tgaagaactt gtcggctccg gggtgttcgc
     9061 ggccgatccg gttgcgggcg gttgtgtcaa ccttgccgtt ccgaatcgca cgatcgagga
     9121 gtacaacttc cagtccctcg ttcgcacgac cgatccattc ctgttcacgt cgaagccccc
     9181 acgcccgcgt ccgctgcctc cgttatcgcc gacagcgttg accttggcgg cggaactcgc
     9241 ctatggcgtg aacgcactgg acacgcagtt agggcaggct gcggccggcg tcacagggac
     9301 gcagccgagc acgcgcggca cagccgttct acgcaatggc gaggcggcgc tcgatgcatt
     9361 acggctggaa agtcacacct atcgctcaac cggtctcgcc gccgttcgcg cgtggcgtga
     9421 aaccgccgcg aaggacagag tcgtgaacgc catcatggag cgggcttcgt cgctgtcgga
     9481 ggatacgctc cgccatgccc tggccgaccc ggacggcttt acgcccgtcg ccctcatgac
     9541 cgccgaacgg catcgcgcgt tcgagcaact cggacaagcg tcggagacga ctcccgcaag
     9601 cggcagaacc ccgatcgccg ccggcaacat gccgcagtgg gatgctcagc cgaagacgta
     9661 ccaggctgcc accatcgcgc acggacacct gcttgagtgg cggcaggtgt ggcgcgccga
     9721 cggctactcg ctcggcgatc tgctctactc gctgccgctt gcaccggggc aaaagcgcca
     9781 gatcgtggtc gtcgactggg atcgccggga gaccggcatg cgaacggaat cgcgcaccgt
     9841 agccgaatct ttcagcgcgg acctgagccg ggatcgagac gttgccgaga tcgtgaactc
     9901 caccatcacc gaaagcattc gcgccggttc cagtacgcgc acctggggcg gcggaggcgg
     9961 tctggggctg ggcattccgt tttcgggagg tttctttggg ctcggagtgg ccggcggggg
    10021 cggcgggtcc gactctcaag cctggcagaa ttccgcccgc tcgttaagcg catcggcggg
    10081 acaagacatc tccgaccgca cgcagcaggc agccacagcc gtgcgtagcc agcgcgcgac
    10141 cgtcgtcacc ggccgccagc agcacgaatc tgtatcggtc accgcggagg tggtcgccaa
    10201 ctacaatcac tgccattcca tgaccgtcga gtacttcgaa gtcctgaagc attaccgcgt
    10261 ggatctcgag cttgcgtccg ctcagcagtg cctgttcatc ccgctccaga tgacgcgctt
    10321 tgacgagatg aagtcgctac gctggcgcga tgttctctcg caacacctcc gcgaccgcac
    10381 gctggcaggc gggttcgatg ccatcgagcg cattcttacc ggatatgtag acagcgattt
    10441 tccgcccgcc cggtacgccg acgaagcgat gaccgagctg tggggcgaac tccgcgtcga
    10501 actcgatatc cgccggccgc gggagccgcg cgagaacgaa gacatcaacg actacctgaa
    10561 taacaactgg aatacatgga atatcctgtt cggccccggc gccgccgcgc gagcctatga
    10621 ccagagcgtc cgagagcgcg ctttggccga caagatcttc gccgatgaac tggcgcctcg
    10681 cattgccagg gcgttcgcgg acacgctgca gttcgagctg tgcgtcgatg tcaacggaac
    10741 cccggtgtac gttccggtca ctgccgactt caccatggtc tcggactatc gtgcgggccg
    10801 cgagcatctc attgccttcc gctgcgtcct cccatcaaat cagcaggtcg cgcgcgctcg
    10861 catcaaggcc gttcgatttt ctacgacact cggcgagatc actccgggct cccgcagcat
    10921 cctccgctac gtgcatgtca gttatcgcaa ccgctaccgc agctttgcgt tgctgtctcc
    10981 ccggagagta cgtgacgaga tcaaagccgg agacgcggta ttcctcgcca cgtacgcttt
    11041 ggcgaaatgg gaggagctga acccgcggtt ggaagacttg cgcctgcgcg atcgtcttct
    11101 caagcatctc aacgagcatg ttgagcacta tcatcatgtg atctggtggc tcatggatcc
    11161 aggcagacgt ttcatgttgc tcgacgggtt catcgccccc gattccgaag gccgttcagt
    11221 cgcctccgtg accgaaaacc ggctcatcag catcataggc aactcgcttg tgctgcccgt
    11281 tgcacctggt tatgtactgg atcccgtcgt aaagaatgcg gaggatccgg acaggcccat
    11341 cgacctactg gaggcctacc gtccggcgat tccctttgcg ccaaagcgaa tcagcgtgcc
    11401 gacacgcggt gtccacgccg aagccattct gggcgagtgc aacagttgtg cgatcctcga
    11461 caacaagcgt ttctgggact gggcgtccga gccgattgaa gaggagccga cgccgattca
    11521 ggaaacctcc acggagacgc gccgccagac tccgcccgac acggaaccga cgcccttcac
    11581 ggcgccgatc gtcggaatcc agaacgtgcc cgaagcgccg gcgcccactg cgctcaccga
    11641 tttcaccaag ctactcgggc agaaggatct gttcaaggac gtcaccggcc ttgagttgaa
    11701 ccaggccaat gctctggggg cgttccagcg agctatgcaa acggcgaact tcttcggcaa
    11761 gatggcggcg gctggagcga aagcctcatt cgcgaatcgc caaagcgaaa acgtcatgaa
    11821 gaaggtcacc gaagcggtga agaacggcga catgagcaag gaagacgcca aaacggtcat
    11881 cgataagctg atcggttcga tgaacggaac gggtggcgaa agcgacaagc cgctcaccgg
    11941 cgaaaaggcc gtcaaggatg cgttgaacaa ggtcgtcagc ggttccggaa aagtgaatgt
    12001 ctccagcgaa agcggcgacg gcaaacaaac agtcgaggcg aagttcgcag acaaaaacgg
    12061 aagcgcacaa tccaccgatg tgcagattga cggcgtgccc gctgtcgacc aggtcaagtc
    12121 gcagggttgc tgggcggcag ccctcacgat gctgatctcg tttcagcgga aggcaaccat
    12181 gccgattgag acggtcctcg ccgaaggcgg accggagtat gtcgagaagt atcaaagcaa
    12241 cggagggatc aaaccttcgg aaatcgcagc gctcaaggac acgttcaagc tgcgcgatgc
    12301 cagcagcgga gccatcacgc tggcgtcgct ttcgagccgc ctctccgagc gaggaccgtt
    12361 atggatcgcc gtcgatgacg atccctcgca acagttctcc gcacatgcgc gggtgatcac
    12421 cggactcaag ggaaacatgg tccggtttat cgatccggat ggtggagtgg aaggggaaga
    12481 ggaattcgtg gtgctcgttc gacaactgaa cgaattgagc aaaggcgtaa ggagtgcgtt
    12541 tggcggatac gccccgctga ttctctctct ctagagcagt ttgcatttaa acagacacat
    12601 accctgccga tttgaagtag ttggcgcatt cctgcggaga gaaggcgtcg aggagtgttc
    12661 cgatttcgtt ccaaagcgcc tcgacggtgc ggtgagcggc ttttttgagc aaggctttga
    12721 gcttggagaa gaccatttcg atggggttga agtccgggga gtacggcggc agatagcgga
    12781 tggtggcgcc gaccccttcg atggcttcgc gcacgtcgtc gttcttatgg ctgccgagat
    12841 tgtcggcaat gacgatatct cctacgtgca gtgccggaca gaggaactcg cgcacgtaga
    12901 cgaggaacgc ttctttgtcc atggggccgt cgagcaccat cggcgcgatc acggccccca
    12961 cgcgtagccc ggcgatgaag gtggtggtgt tccagtgtcc gcccggtacg ctgtgaaata
    13021 tgatcttctt ggcaagctgg cggaagcgac ccagctcact cggcggacca ttgccaccat
    13081 cctgcgcggt atcaacctcg ccgtactggg tcaatacaaa accaaccctg aagatttcat
    13141 tttgaaggca ggcacactca ttaatgaaca aaaagccacg gtgatcatcg agcatctgac
    13201 gtacaatcca ctggaagaga cccacaccat cgacatcttc gcacagcaaa agaaggaaga
    13261 tctgagcaag gggttcaagg ccaaccgcca catttacgat tacgttctta ccgattccag
    13321 caatgagcgc acgtttgtcg gcgaactcga tgccagttct gaagtcgtgg tgtatgccaa
    13381 gttgcccaaa gccttccaca ttccaacccc agtcgggaac tataatccag actgggctat
    13441 tgcctttgag gccggacaag tgaagcacgt ctacttcgtg gcggagacca aaggctcgat
    13501 gtcgtcaatg gacctgcgga agatcgagga aactaaaatc gaatgcgccc gcaaattctt
    13561 tgccaaaatc acgtcagacc aggcgaagta tgacgtcgtg aacagctacg gaaagctgat
    13621 ggaactggtg aagtaggcga ggacctctgt tcgctctaat cggcctgctg ccggtttagt
    13681 tgacaccatc ctacgctcat ttagcctgcc gttcgaactc catcggactg agatacccca
    13741 acgtggagtg ccgccttcga cgcccgccac ctcacgaaac aaatcaggcg catggaacaa
    13801 tgcgttcaat ccgatccggc tcacgccatc ggaacggcca aagagctgat cgaaacctgt
    13861 tgcaagacca tccttgcaca gcgcgggaaa tcgcttcctg ggaaacctga tatcccggaa
    13921 cttaccaaag ccaccctcaa ggaactgaag ctcgttcccg acgatgtaga agattcagcg
    13981 cgcggcagcg acattattaa acgcctcctt caaaatctcg gaaccatcgg aaacaacctc
    14041 gctgagctac gcggccttta cggcaccggg catggcaagc atgcccatac gggaacactg
    14101 acaccacgcc atgccagact tgccgtcggc gcagcatcca ctctcgctac attcctcttc
    14161 gatactcaca gagagagagc aagttgactg tcgctaagaa catgcagcat acgaatcagt
    14221 atctgtacgg acgtacagag agcctcagct ccccgcgctt cacccaaggc cggtaccgct
    14281 gatgtcctgg agccgcactt tcacgttaat catgccgatt gacattgtag gctcttccgt
    14341 cttcctgggc atgaccgttc ttagcagacg tcatacaagc gattgcgtcg tttttcttcc
    14401 gccgcctcgc gaccgccaat cacaaaatag acataaggaa cacagagagt ggcaatagtg
    14461 accagaataa ccattgtcgc cgacggaatc atgacttcac gcatactgat cacccagtcc
    14521 tgcaccccga ctaccatctg atcggacatc actccccgga gtatcggcca gagcagcttg
    14581 accccctcct gtacatgttc cggcgtcaag agctgataca taaaattaaa aaagaccgac
    14641 aggagaatga ccttgatgat gttggccacg atcatcgact gatatatgtc ctgaatggcc
    14701 cgtttgcaga cctttccgat gtaacaggag ccgaggttat gtccaatcat gaccgcatac
    14761 cccacgccgt aggtgacccc aatgagctgc gcgaatacct gatcgaagag gctcggatct
    14821 ggatctccga agatcggcat caagctccct aagacgccca gtcccatcgg tacccctagc
    14881 atgttgatca gcccatcgac cacgacgcta tgcacgccca cctcggtata ggcaaagctg
    14941 cgatcgagca gaatgagatg ttccggaagc ggcgtaccga gcttctcgac caccgccaac
    15001 tcctgaattt cgctgatcgc cgcaatcaga cttcgcggac ggcttcggcc tgaagccccc
    15061 tccgcaaaga tcggtcctcg ccgcgccgct gattgctcca ttgttacatg ctccccgagc
    15121 cgatcaggtt gatcagtggt cgaaaatatg ccagcagaat cgtcagcatg aaaaataaga
    15181 accccagcgc aatgcgctgt ttgtaggccc caaaccagaa cgtcgctgcc agagtggcgg
    15241 aggccaggat ccggagcggg acaccggcca gcagcgtcgt attcacccac gatgacacgg
    15301 caataaatgt ttccgggtcc atatacctgc actcctatcc tcgaccgagt tggaattcgg
    15361 tcactaactg cataaaggcc accttgcgag actcgagttc cgattcggcg atccgaaatg
    15421 cctccaattt gaccggcacg aaatagcccc gctgtttgat ccccgctttc ttcgtgaaaa
    15481 tgtcgaacgg ccggccgtag aaatgctccc caatctccat ggccaagaga tctgcagcac
    15541 ccaggatttt caccagtctc cggagcgtat cctctcgatc ggtcgatcga atgagtccca
    15601 tttcgacgat cttcttctgc cgtgccagct ctttggccgc ctccagaagg gcgtcgggcg
    15661 tcacatagac gacccctttg agggaaaacg ccgcccactt atttcctttg agtggacgat
    15721 tgatccgagg cgccacaatc gccaagacct ctgatcccgc gcaccagctg tctaacggct
    15781 tctcctgcat ctcctgcgta ctgaggatca tctccttcac gcgagcctgc ccatcggctt
    15841 gccgaagaat cacgcccagc cgatccttcc cgatccgat
//
LOCUS       DAOQPD010000092        15493 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1923_length_15493_cov_19.436002, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000092 DAOQPD010000000
VERSION     DAOQPD010000092.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 15493)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 15493)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15493
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1923_length_15493_cov_19.436002"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(195..566)
                     /locus_tag="PK063_16195"
     CDS             complement(195..566)
                     /locus_tag="PK063_16195"
                     /inference="COORDINATES: protein motif:HMM:NF025629.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4359 domain-containing protein"
                     /protein_id="HMZ98642.1"
                     /translation="MRTGTLVGLVGSLMLAVWLAATNPTMDTYLQFVEARLSAEIDKM
                     DQSGPRRDRDLIRSIFRAQGPKLVEGVVRPNTRRNNWGLLSLFETNVLDQPVLVLGIG
                     GQFVPLRGVEEATVKVGRLAF"
     gene            723..1013
                     /locus_tag="PK063_16200"
     CDS             723..1013
                     /locus_tag="PK063_16200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98643.1"
                     /translation="MFVWSKRLVTGLLAGFVLLIGIFLLQGEPETISGLKIHTTRWMA
                     VNYIGLLVWLFVWMFDQARVRGKNVFFWLVPFALAPLPTLMLFILFLQRKMK"
     gene            complement(1054..2319)
                     /locus_tag="PK063_16205"
     CDS             complement(1054..2319)
                     /locus_tag="PK063_16205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HMZ98644.1"
                     /translation="MSHSSIRSYLTPRLGIMLPLGFASGLPLALTGGTLQAWLTEAGL
                     DLTTIGLFAYVGLPYTLKFLWAPVMDRIVPPWLGRRRGWMLVTQSGLALALTVMALIG
                     PAEGAQVFAALALAVAFLSASQDIVFDAYRTDLLKPEERGLGAATWVMGYRIAMIASG
                     SLALILAARLNWSAAYLCMSALMALGIVTILLSPEPEDAQVAPKSMAEAVWGPLSEFL
                     SRPMALALLGLIVLYKLGDAFAGALTTSFLLRGMQFSSEDIGVVRAFGMGATILGAFI
                     GGGLMPRLGLFRSLFVFGVLQALSNLSFMWLAWAGKSYAVMAFAVGAENLTGGMGTAA
                     FVALVMSLCNHRYTATQFALLSSVEALGRVFLGWPAAKLVGLAGWGPFFFVTFLAALP
                     GLWLLWVLRKPVAQHAELNAGRSAAGAPC"
     gene            2545..2949
                     /locus_tag="PK063_16210"
     CDS             2545..2949
                     /locus_tag="PK063_16210"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98645.1"
                     /translation="MNVTNLGFTWNSRYLELSPTEMAIALVAALLVGGAALYFLLKVL
                     RSKPVKVLGMALLVAGIALVGWLALDQHQQDERARVSEIWSRTFENSAIKDFESCVAN
                     RTPRSPGPQYRVEVVTECGDVAKAIKEGLEAR"
     gene            complement(3014..3859)
                     /locus_tag="PK063_16215"
     CDS             complement(3014..3859)
                     /locus_tag="PK063_16215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HMZ98646.1"
                     /translation="MTAEPVPSATGSVADAYPPPEIAARVCKLGLAKVNTAVPTMVAL
                     AVLAGAFISLGALFYTVTITAGQDGSPLPFGLLRLTGGVTFSLGLILVVVGGAELFTG
                     NNLIAMAWAAGCVQTRQVVRNWIWVYLGNLLGACGTAGLVLLAGIQLLGDGAVGEAMV
                     RIARSKIALDPLSAFARGILCNVLVCLAVWLCMGARSVADKILAIVFPISAFVACGFE
                     HSVANMFFLPLGIALAAGSAAPLSLIDALSNLALVTLGNIIGGTVLVALVYWFIYLRT
                     GSQPR"
     gene            complement(3856..6579)
                     /gene="fdhF"
                     /locus_tag="PK063_16220"
     CDS             complement(3856..6579)
                     /gene="fdhF"
                     /locus_tag="PK063_16220"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: protein motif:HMM:TIGR01591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009326 - formate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0008863 - formate dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_process: GO:0015942 - formate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HMZ98647.1"
                     /translation="MKLSINGRVIVASPGDSIYRAAKQAGIGIPGLCTSDHLNPFGSC
                     RLCLCEVEGQSGTPASCTTPVREGMVVHTESERLTRLRKHLLELYLSEQPAGDRVPEP
                     LQALARSLGLTHVRYLQPAGRVPVVDRSNPFFVFDNAVCISCARCVRACDEIQGTHAL
                     TMLYRGFSSRPAAGAAALSGEAAGFASSNCVSCGSCVKECPTGALIEKTVLEEGEPVQ
                     AVRTTCAYCGVGCTFDAGVREGRVVRMGPADDGPSNHGHACMKGRFGWTYNYAPDRLR
                     TPLLRQGDKWVELSWPAALDRIAEEWSRIKEAHGPDALATISSSRGTNEENYLFGKFM
                     RCVIGSNHIDNCARVCHSATVTGMMETLGASAATNSIHDLDLAKLILVVGANPTESHP
                     VLGARIKQAARRGVPLIVIDPRRTELARLADLHLQLHPGTNVALLNGMGHVIAKEHLT
                     DAAFVRDRTEGFEEWLNVVEGCTPELTSRLTGVPAHLITEAARRYATSGGSMAVHGLG
                     MTEHRWGSHGVMALVNLALATGNIGKPGTGINPLRGQNNVQGASDVGCLPTFFAGYQP
                     LTDPALAAAHLAVTGRPLPTARGMKTPDMWDAALAGTLKSLWIIGYDVAQTDPNLKKV
                     HAALKQLDFLIVQDLFFSETAKLAHLVIPGASFLEKDGTFTNLERRIQRIRKAVEPPD
                     GVLPDWQVVCEVSARMGYPMQYSHPSAIMDEIAQLAPLFAGVSFDRLDAPEGLQWPVP
                     SKDHPGTSLMHEQSFPKGKAKFVAVDYLPPGETPSEAYPLVLITGRILQHYNCGAQTR
                     RTEIMQVVDTDVLEMHALDATRLDVRDGDPVRLISARGEARLPVMISDRVQPGELFTS
                     FHFPDSDLNVLLSSSADESSKCPEYKVSTVRVEKVLSTGTPTPSMHVMLIT"
     gene            complement(6609..8120)
                     /locus_tag="PK063_16225"
     CDS             complement(6609..8120)
                     /locus_tag="PK063_16225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-ubiquinone oxidoreductase-F iron-sulfur
                     binding region domain-containing protein"
                     /protein_id="HMZ98648.1"
                     /translation="MTSATRLYLSNDTSARAAGAGVLADAWAERPEVQLIRISSRGAF
                     FLEPMVERDSPEGRIAWFNVQPDDLASILSCNGGTPVRAIPFLANQTRFTFANFGETE
                     PLALDEYQARGGLKGLEESFRLTPDAIIEELRQSQLRGRGGAAFPVWNKWKVAQQTRA
                     SEKYVVANADEGDAGTYCDRMILEGDPFRLLEGMLICARAIGASRGYVYCRQEYPAAA
                     ATLRAAIHKADEAELLELRGEPFPIEVVEGAGSYVCGEETALLESLEGRRGVVRARPP
                     YPAQAGLYGHPTIVSNVLTFATIPQILSRGGAWHASLGTEQSRGTIALQLGGRVKHPG
                     LVEVPFGLSLRQVLDQFGGGMAPGSRFKAAQVGGPLGSLFPAAGLDLPICYDAFAKAG
                     AVLGHGGIVIYDHETDMVDLARHFMAFTAQESCGKCTPCRIGSVRGREILERIQAGGG
                     TVEDLALLDDLGETMKLTSLCALGGRAPYPVLTAIEHFPVEFRNKLSAVRRQS"
     gene            complement(8122..8613)
                     /locus_tag="PK063_16230"
     CDS             complement(8122..8613)
                     /locus_tag="PK063_16230"
                     /inference="COORDINATES: protein motif:HMM:NF013426.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HMZ98649.1"
                     /translation="MAQDRRTMMDGGEGMQEQVERIVLQARAEPPNVLKTLLAIEEHL
                     GHVPAEAIPVIARRLGATTAQIAGVLSYYPDLRVTAPGRHVIRVCMGESCYANGCGRV
                     LRELQDRLRTDVGETTSGGKFTLDTMSCAGNCAVSPTVVIDRDLYGRVLPSQVETMLE
                     RYR"
     gene            complement(8632..9987)
                     /locus_tag="PK063_16235"
     CDS             complement(8632..9987)
                     /locus_tag="PK063_16235"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98650.1"
                     /translation="MNLANERVVGRSAPVNKDLGRLISRLDQLSLSPGFAQQRRIAFE
                     RALQVYVELGSQSPLTPLREEVELADLLLYADFYPEDGQLTLIEQLRDVITEHIPEEE
                     RVWLDPLKHSYLDLVEILPSQAGAARRSLKSLGDGRLYDIPAESVPRDAALGSVLFTR
                     LVREPGDPESRLAVLAGPMLVLSIQDARALYETTGEERREMEVVGGSFELGDWPEFAK
                     RFGHLLLKNFARMRLAALLEAVSDIRYRTETDAPYFYVMALYEHHEFTFISGGMTELE
                     GWAEDAPPEQAVTGSRRKLRRFVRRGQKELVARITVTATELFLECDSRGSLDEIKHTL
                     AATFGYSLHFRGEIAQPPVRQVTQEELSGNEPLTVVVTGEEDRSLVKGFLETVYLEWA
                     DRESPALGGDTPRHTAKTPEGRDRVAALIDDMERCDFGLVRSGIAAFDYNVLRAHVGL
                     C"
     gene            complement(9971..10195)
                     /locus_tag="PK063_16240"
     CDS             complement(9971..10195)
                     /locus_tag="PK063_16240"
                     /inference="COORDINATES: protein motif:HMM:NF022603.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2934 domain-containing protein"
                     /protein_id="HMZ98651.1"
                     /translation="MKRKEQSRAAAPPSPRAKEQTAVNPSALPDGMWERISQKAYDLW
                     RERGSREGFALEDWLDAEAIVMEEMHESRE"
     gene            complement(10226..11164)
                     /locus_tag="PK063_16245"
     CDS             complement(10226..11164)
                     /locus_tag="PK063_16245"
                     /inference="COORDINATES: protein motif:HMM:NF012791.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016208 - AMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HMZ98652.1"
                     /translation="MVPLIKHMLFATDFSACADRAMGYALSLAGAWKANLCVVTVLEL
                     YPGMDPDYTVNKMYLDHLREEANRQLGAVQARAKAASQSVTTRIEVGIPSQALQTVAE
                     STGADLLVVGTHGRTGLDHVLVGSTAERVVRVSPCPVLAVKADKGVADSSAAAPIKRI
                     VVPVDLSTCSLDALEYAVQFAKPLGAAITILHAMEPVAYGLDFSLSHAKEWKEQRDYL
                     EKRLSVLSACVTAHGIQADHVLKPGLPADSIVSHVTQQGFDLMIMGTHGRRGISHVLL
                     GSIAGAMLRHAPCPVLTVLQVNFGADYERVVPLGNS"
     gene            complement(11168..11596)
                     /locus_tag="PK063_16250"
     CDS             complement(11168..11596)
                     /locus_tag="PK063_16250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HMZ98653.1"
                     /translation="MGLKQRSAVLSGGRVWLAICFVLALCSQGGAQAEQRIDVAIKDF
                     AFVTKQVPLRLGVATVITITNEDQERHDFGSTMFDGLPTRVESGGIVSYGRGISGVFL
                     DGKKSAVIRFVMERPGRHEFRCSIHQNMKGELLLLNVEAA"
     gene            complement(11609..12112)
                     /locus_tag="PK063_16255"
     CDS             complement(11609..12112)
                     /locus_tag="PK063_16255"
                     /inference="COORDINATES: protein motif:HMM:NF012791.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HMZ98654.1"
                     /translation="MVERLFTKILVPVDFSPCSEEAYRIALSFARSYQAEVLLLHVVD
                     TKSLDALNRLGLAPASEAAKQKKQLHHHARLNARQLLAWDEAKGLSIKRVLADGCPFE
                     EIARTARVEGVDLVVMGSYGGAVGGVEKIFFGTTAEKVVRTAGCPVLTVPLPVKRAKA
                     RSGKSSS"
     gene            12588..13262
                     /locus_tag="PK063_16260"
     CDS             12588..13262
                     /locus_tag="PK063_16260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HMZ98655.1"
                     /translation="MRMESISQITITGDGIALDGILGLPGQPKGVIAFAHGSGSGRFS
                     PRNQFVARVLETGGFATLLLDLLSPDEADDRRKIFDIDLLADRLLLAQHWLQTHASTR
                     TLRTGYFGASTGAGAALQAAAREPDAVGAVVSRGGRPDLAGPYLSRVIAPTLLLVGGE
                     DGPVIGMNEEALGQLTCQKRLIIIPGATHLFEEPGTLEQVAQEALNWFRRYLHPAPYQ
                     PKELLP"
     gene            13259..14122
                     /locus_tag="PK063_16265"
     CDS             13259..14122
                     /locus_tag="PK063_16265"
                     /inference="COORDINATES: protein motif:HMM:NF012791.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016208 - AMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HMZ98656.1"
                     /translation="MNTLLAVDGSDHAYEAVRALKYLRRADQLTLLHVVDAPRPAYPM
                     MVPEVAQELYAQLERSMKEDGEELLTRIQSLLPLHSGPVTKLLQVGSPAEHIVAAAQS
                     CQADLIVMGARGLGPVKERLLGSVSHRVLSMAPCAKFVLHGSLRQLKHILLPLQGPSD
                     AEAALRFLAKQPFQEPVNVSVLTVLPPTRPPWPIDDTAAEKLEAHALRHARDFVEDVA
                     ATLRTQGYTTRSASVLGSPLTMILHEAEKLGADLIMVGSRARQGITRFVLGSVSHAVL
                     HRAPCQVLVFE"
     gene            complement(14589..15110)
                     /locus_tag="PK063_16270"
     CDS             complement(14589..15110)
                     /locus_tag="PK063_16270"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98657.1"
                     /translation="MTIKLPAIIPAIVLMSVVLSGCPLPRSEMYKGFSEAEKSYFATA
                     DLGVFPNDARKDVERYQASLVAWPGFITELNSIQKDSAYFTRIVVEHHYYDWILDHSI
                     QKEKYFLSPRGEGVFTTLCPSKLKDENVTKDLNNMLIVYGKPEKVEDGMLHVTCDYAA
                     FIKREWVRTDIFD"
     gene            complement(15138..15299)
                     /locus_tag="PK063_16275"
     CDS             complement(15138..15299)
                     /locus_tag="PK063_16275"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98658.1"
                     /translation="MSVAYRQYGYRLDEIAMHRGVHYATISRCMKQAEQETNDSNDPA
                     PPGMCDCKT"
BASE COUNT         3254 a         4931 c         4317 g         2991 t
ORIGIN      
        1 actagatata gtgatcccat ttttttgtca aacaaaatgt tgtggcacac ctgtgggtaa
       61 tggggataag ctggtgatag cgtctccgct aggtttcatg cagcttttct ccattttttg
      121 ctgagttatc cacaggcgtt cagagactgt ggaggaagtt tttcacaggg gagcgagaaa
      181 aatgctggca caaatcaaaa tgcgagccga ccgaccttca ccgtcgcctc ctcgacccct
      241 cgtaacggga caaattggcc tccgatgccc agcaccagca ccggttggtc cagcacattc
      301 gtttcaaaca gactgagcag gccccagttg ttccgtctcg tattgggccg gacgactcct
      361 tcgacgagct tcggcccttg tgcgcggaaa atcgaacgaa tcagatcgcg gtcgcggcgc
      421 gggccggatt gatccatctt atcgatctca gcggacaagc gcgcttcgac gaactgcaga
      481 taggtgtcca tcgtcggatt ggtcgccgcc agccacaccg ccagcatcaa acttcccacc
      541 aatccaacca gggtcccagt acgcatcaca caccttcacc ttgccgccgc acgatcgttg
      601 cgcgccggga gcaaccacgg tttgacaaat gcacctcgtc tgtttagctt acgcccgatt
      661 tccaaggaat ggaatacgaa ggcgcgtgat cgcgccggtt cgacagtcac ggaggatgca
      721 ctatgttcgt ttggagtaaa cgcctcgtaa ccggtctgct ggcaggtttc gtcctgctga
      781 tcggaatctt cctgcttcag ggagagccgg aaacaatcag cggcttgaag atccacacca
      841 cccgctggat ggcggtgaac tatatcggcc tgctggtgtg gctgtttgta tggatgttcg
      901 accaagcccg ggtgcgcggg aaaaacgtgt tcttctggct ggtgccgttc gcattggcac
      961 cgctgccgac cctgatgctg tttattttgt ttctgcagag gaagatgaaa taggaacaga
     1021 cggcacacct gcgggaagag ttttgctcag gaactaacag ggcgctccgg ccgcggacct
     1081 ccccgcattc agttccgcat gttgggcaac cggcttacga agcacccaca gcagccacag
     1141 acccggcagc gcggcgagga aggtcacaaa gaaaaacgga ccccacccgg ccagccccac
     1201 cagtttcgcc gcaggccaac cgaggaacac gcgaccgagc gcttcaacgg atgacagcag
     1261 cgcgaactgg gtggcggtat accgatgatt gcagagcgac atgaccagcg ccacgaaggc
     1321 ggcagtgccc atgcctccag tcagattttc ggctcccacc gcaaacgcca tcacggcata
     1381 gcttttcccc gcccaagcca accacataaa tgacaggttc gagagggcct gcaggacacc
     1441 gaacacaaac agcgaacgga acagccctaa acgcggcatc aacccgccgc cgataaacgc
     1501 gcctagaatc gtggctccca tcccgaatgc gcggaccacc ccgatatcct cggaagaaaa
     1561 ctgcatcccg cgcagcaaaa acgacgtcgt cagcgcgccg gcgaacgcat cgccaagttt
     1621 atagagcacg atcaaaccga gcagcgctaa cgccatagga cgggaaagga actcgctcag
     1681 cggcccccag accgcttccg ccatcgattt gggcgccacc tgcgcatcct ctggttccgg
     1741 actcaggagg atcgtcacga tacccaatgc catcaaggcg gacatacaga gatacgccgc
     1801 cgaccagttc aagcgggcag ccaggatcag ggccaacgaa ccggatgcaa tcatggcaat
     1861 ccggtagccc atcacccagg tcgccgcgcc caatccccgt tcctcgggtt tcagcaggtc
     1921 ggtccggtac gcatcgaaca cgatatcctg cgaggcggaa agaaacgcca cggcaagagc
     1981 caaggccgca aacacctgcg cgccctcagc cgggccgatc aaggccatca cagtcagggc
     2041 aagcgcgaga ccgctttggg tgacgagcat ccacccgcga cggcggccga gccagggcgg
     2101 cacgatccgg tccatcaccg gcgcccagag aaatttcaag gtatagggaa ggccaacata
     2161 ggcgaacagg ccgatcgtcg tgagatccag cccggcctcc gtcagccatg cctgcaacgt
     2221 tccgcccgtg agggccaggg gcagacccga agcaaacccc agcggcagca tgatgccgag
     2281 gcgtggggtc agatagctgc gaatggatga atggctcata ggatcaagag aacagcaggc
     2341 tcacgaggtg cagcatacca ttgcccgaga cgctgacggc atcagaatcg tgattctttc
     2401 tgtaaggatc cggaacgata ctgtttacag gccgccggaa actcgagcgc tgtacgatct
     2461 cttcccgcca aacttctccg gtatgaatca gaggaggctt ttgtatagct gaactggtat
     2521 aagtagcaaa acgagaggga tgagatgaac gtgacaaact taggcttcac gtggaattcc
     2581 cgatacctcg aactgtcgcc gacggagatg gcgatcgccc ttgtggcggc ccttctggtc
     2641 ggcggagcgg ccctgtattt tctcctcaaa gtcctgcgca gcaagccggt caaggtgctc
     2701 ggcatggcat tgttggtggc cggaatcgca ctggtcggct ggctggctct cgatcagcat
     2761 caacaggatg agcgcgcgcg cgtctccgaa atctggagtc gcaccttcga aaacagcgcg
     2821 atcaaagact tcgaatcctg cgtcgccaac cggacacctc gcagcccagg gccgcaatac
     2881 cgcgtggagg tcgtgaccga atgcggtgac gtggcgaaag ccattaaaga agggttggag
     2941 gcccgctgac cggtatccta gccgcccgaa ctctacctgc cgtcccctgc caacataaac
     3001 cacaggatgc tcttcatcgt ggctgggaac cggtcctgag gtagatgaac caatagacta
     3061 gcgcgactaa cactgttccg ccgatgatgt tcccgagggt gaccagcgcc aggttgctca
     3121 gggcgtctat gagcgacagg ggcgccgcac tgcccgccgc cagcgctatc cccagcggca
     3181 aaaagaacat gttcgccacg gaatgttcga agccgcaagc gacgaaggcg ctgatgggaa
     3241 acacaatcgc gagaatctta tccgccacgc tccgcgcacc catacacaac cagaccgcga
     3301 gacacaccag tacattgcac aaaatgccac gcgcaaaggc agacagcgga tcgagggcga
     3361 ttttactgcg cgcgatacgc accatcgcct cgccgacagc cccgtcccct agcaactgaa
     3421 tccccgcaag caacaccagt cccgccgttc cgcaggctcc cagcaagttt ccgagataga
     3481 cccagatcca attcctcacg acctgacgcg tctgcacaca accggcagcc caggccatcg
     3541 caatcagatt gtttccggta aacagttccg ccccgccaac cacgaccaaa atcaggccca
     3601 ggctgaacgt gacgcccccg gtcagccgca agagtccgaa tggcaacggc gaaccgtctt
     3661 gtcccgccgt gatcgtgacg gtgtaaaaca aggcgcccaa cgaaatgaac gcgccggcca
     3721 gcacggccag ggctaccatc gtcggcaccg ccgtgttcac cttggccagc ccgagcttgc
     3781 acacacgcgc ggcgatttca gggggcggat aggcgtcggc gaccgagccg gtggcggaag
     3841 gaactggctc ggcagtcatg taatcaacat cacatgcatg gagggagtgg gcgtcccggt
     3901 cgacagcact ttttcaaccc gcaccgtcga gactttgtac tcaggacatt tcgaactttc
     3961 gtcggcgctg gatgacagga gcacgttcag gtccgaatcg gggaaatgga aactcgtgaa
     4021 caactctccc ggctgcacgc ggtcactgat catcacaggc agcctggcct ccccgcgcgc
     4081 gctgatcagc ctgaccggat cgccgtcacg gacgtccaac ctggtcgcat cgagcgcatg
     4141 catctccagc acatcggtat cgaccacctg catgatctcc gttcgcctcg tctgcgcccc
     4201 gcaattgtaa tgctgcagaa tcctcccggt gatcaatacc agcggatagg cttcgctcgg
     4261 tgtctccccc ggcggcaggt aatccactgc cacaaacttc gccttgcctt tgggaaacga
     4321 ctgttcatgc atcaatgatg tgccgggatg gtccttcgag ggcacgggcc actgtaatcc
     4381 ctccggcgca tccagtcgat cgaacgacac cccggcaaac agcggcgcga gttgcgctat
     4441 ctcatccatg atggccgagg gatgggaata ctgcatcgga taccccatcc gcgcggagac
     4501 ttcgcagacg acctgccagt ccggcaacac gccgtctggc ggctccacag cttttctgat
     4561 gcgttggatg cggcgctcga gattcgtgaa ggttccatcc ttttccagaa atgaggcccc
     4621 cggaatcacg agatgcgcca gcttggccgt ttcgctgaaa aacaaatcct ggacgatgag
     4681 aaaatcgagt tgcttgagcg ccgcatgaac ttttttcaga ttcgggtcgg tctgagccac
     4741 gtcatatccg ataatccaga gactcttgag cgttcccgcc agcgcggcat cccacatgtc
     4801 cggcgtcttc atgccgcggg ccgttggcaa gggccgtcct gtgactgcga gatgcgccgc
     4861 cgccagcgct ggatccgtaa gcggctgata cccggcaaag aatgtgggca ggcagccgac
     4921 atccgatgcc ccctgcacat tgttctgccc gcgcaagggg ttgatcccgg taccgggctt
     4981 cccgatgttg ccggtcgcca gcgcgagatt caccagcgcc atcaccccat ggcttcccca
     5041 gcgatgttcg gtcatgccca ggccatgcac cgccatggag ccgccgcttg tggcatatcg
     5101 tctcgcggct tcggtgatga gatgagcggg cacgccggtc agcctcgacg tcagttcagg
     5161 agtacaaccc tccaccacat tcagccattc ctcgaacccc tcggtccggt cacgcacgaa
     5221 tgccgcatcg gtcaaatgtt ccttcgcgat gacatggccc atgccattca gcagcgccac
     5281 gttggtacca ggatgcagtt gaagatgaag atcggccagc cgggctaatt ccgtgcgtcg
     5341 cggatcaatc acgatcaacg gcaccccgcg ccgggctgct tgtttgatgc gcgcgccgag
     5401 taccggatgg gattcggtgg gattggctcc gacgacgagg atcagcttgg ccagatcaag
     5461 atcgtgaatg gaattggttg ccgccgacgc gcccagagtt tccatcatgc cggtcacggt
     5521 cgcgctgtgg cacacccgtg cgcagttgtc gatatgattg ctgccgatca cgcagcgcat
     5581 gaatttgccg aagagataat tctcttcgtt cgtgccgcgg ctggaggaga tcgtcgccag
     5641 tgcatcaggc ccgtgggctt ccttgatgcg actccactcc tcagcaattc gatcgagggc
     5701 cgcaggccag gagagttcaa cccacttgtc gccctgccgc agaagcggcg tgcgcagccg
     5761 gtccggcgca taattgtagg tccacccgaa tcgtcccttc atgcatgcat ggccgtgatt
     5821 ggaaggcccg tcatcggccg gtcccatccg gacgacccgc ccctcccgca caccagcatc
     5881 gaatgtgcaa ccgacaccgc aataggcaca ggtggtgcga acggcttgca ccggctcgcc
     5941 ctcttcaagc acggtcttct cgatcaaggc ccccgtcgga cattccttca cgcaagaccc
     6001 gcaggagacg caattcgatg aggcaaaccc tgccgcctct ccgctcaacg ccgcagcccc
     6061 tgccgccggc cggctggaga atccccgata caacatcgtc agggcatgcg tgccttggat
     6121 ctcatcgcag gctcgcacac agcgggcgca tgaaatacac accgcattgt cgaagacaaa
     6181 aaagggattg gatcgatcga cgacaggcac tctgccggca ggctgaagat aacgaacatg
     6241 cgtcaacccc aacgatctgg ccaacgcctg caagggttcc ggcacgcgat ctcctgccgg
     6301 ttgctcggag agatagagct cgaggagatg ttttctcaga cgagtgagcc gttcgctctc
     6361 cgtgtgcacg accatgcctt cgcgcaccgg cgtggtgcag gaagccggcg tcccgctctg
     6421 gccctcgact tcacacagac agaggcgaca ggagccgaac ggattcaaat ggtctgaggt
     6481 acagagcccg gggatgccga ttcccgcctg tttcgccgct cgataaatgg aatcacccgg
     6541 cgacgccacg atcactcgtc cgttgatgga aagtttcata atgatgcgcg ctcagcctca
     6601 gctttcagtc acgactgacg tctgaccgct gacagcttat ttctaaattc cacgggaaaa
     6661 tgttcaatgg ccgtcagcac cggataggga gcccggccgc cgagggcgca gagactggtc
     6721 agcttcatcg tttcgccgag atcgtccagg agggcaaggt cctcgacggt gccgccgccg
     6781 gcttgaatcc gttcgaggat ttcgcgcccg cgcacggaac cgatccgaca gggcgtgcac
     6841 ttgccgcagg actcttgggc ggtaaacgcc atgaagtggc gcgccaaatc aaccatgtca
     6901 gtttcatggt cgtagatgac gatcccgcca tgaccgagca ccgcgcctgc cttggcaaag
     6961 gcgtcataac aaatcgggag atccaatccg gcagcgggaa acagactgcc cagcggcccg
     7021 ccgacctgcg ccgctttgaa ccgtgagccg ggggccatcc cgccgccgaa ctggtccaac
     7081 acctgacgca ggcttagccc gaacggcacc tccaccagtc ccggatgttt cacccgcccg
     7141 cccaactgca aggcgatagt gccgcgcgac tgttcggtgc cgagagacgc atgccaagcg
     7201 ccgccacgcg acagaatctg tgggatggtg gcaaaggtga ggacattact cacaatggtc
     7261 ggatggccat acaaccccgc ctgtgccgga tagggaggcc tggcccgcac gacaccccgc
     7321 ctgccctcca gcgattccag caacgccgtc tcctctccgc agacatagga ccccgctccc
     7381 tccaccacct caatgggaaa cggttcgcct cgtagttcca gcagctcggc ttcatcggct
     7441 ttgtgaatcg ctgcgcgcaa ggtggcggcg gctgcgggat attcctgccg gcaatagaca
     7501 tagccgcggg aggcgccgat cgcccgggca cagatcaaca tgccttccaa caatcgaaac
     7561 ggatcccctt ccaagatcat gcgatcgcag tacgttccgg catccccttc atcggcgttg
     7621 gcgaccacat atttttctga cgctctcgtc tgttgcgcca ccttccattt attccagacg
     7681 ggaaaggccg ctcccccacg tcctcgtaac tgcgactggc ggagttcctc gatgatcgca
     7741 tccggcgtaa gacggaagga ctcctccagt cccttcaggc cgccgcgcgc ctggtattca
     7801 tccagagcca agggttctgt ctcgccgaag ttggcaaaag tgaagcgggt ttgattggcg
     7861 agaaagggaa tggcccggac cggtgtcccg ccgttgcatg acagtatgga tgccagatcg
     7921 tccggttgaa cattgaacca ggcgatccga ccctccggac tgtcgcgctc gaccatcggc
     7981 tcgagaaaaa atgctccccg tgaagagatg cggatgagct gcacctcggg gcgttcagcc
     8041 caggcgtcgg ccaacacacc agcccccgca gctctggccg acgtgtcatt ggaaaggtag
     8101 agtcgcgttg cgctggtcat gttaccgata gcgttccagc atcgtctcga cttgcgatgg
     8161 caacacccga ccgtacaggt ctcgatcgat cacgaccgtc ggagagacgg cacagttgcc
     8221 ggcgcatgac atggtgtcga gggtaaactt tcctcctgag gtcgtttcgc ctacgtcggt
     8281 gcgaagacga tcctgcagct cccgcaagac ccggccacaa ccgtttgcat agcacgattc
     8341 tcccatacag acgcgaatga catggcggcc cggggccgtc acccgcaaat cgggatagta
     8401 ggacagcacc ccggcgattt gcgcggtcgt ggcgccaagt cgccgcgcga tgaccggaat
     8461 cgcttcggcc ggcacatgcc ccaggtgctc ttcaatggcc agaagcgtct tcagcacgtt
     8521 gggcggctcg gcgcgagcct gcagcacaat cctttcgacc tgctcctgca tgccctcccc
     8581 tccgtccatc atcgtccgtc tgtcttgcgc cacaggaact ccgtgctcac atcagcacaa
     8641 gccgacatgc gctcgtaaga cgttgtagtc gaacgctgcg ataccgctgc ggacgagacc
     8701 gaaatcacag cgttccatgt cgtcgatgag cgcggccacc cggtcgcgcc cctccggcgt
     8761 tttggccgta tgccgcggag tatcgccgcc caacgcagga gattcccggt ccgcccattc
     8821 cagatacacc gtctcaagga aacccttcac cagcgatcga tcttcttcgc cggtcaccac
     8881 cacggtcagc ggttcgttac cggacagctc ttcctgggtg acctgccgta caggcggttg
     8941 ggcaatttcg cctcgaaaat gcagcgaata cccgaaggtg gccgctaacg tatgcttgat
     9001 ctcgtccaag gatccccgtg agtcacattc caggaacagc tccgtcgccg tcaccgtgat
     9061 gcgcgccacg agttccttct gccctcgccg gacgaaacgg cgaagtttcc ggcggctacc
     9121 ggtcacggcc tgctcgggcg gtgcgtcttc cgcccagccc tccagctcgg tcatgccccc
     9181 ggaaatgaat gtgaattcat gatgctcgta caaggccatg acataaaaat acggtgcgtc
     9241 agtttccgtc cgataccgaa tgtcgctcac ggcttccaat aacgcggcca accgcatgcg
     9301 cgcaaaattc ttcagcagga gatggccgaa ccgcttggca aactccggcc agtctccgag
     9361 ttcgaatgag cctccaacca cttccatctc gcgccgttct tcaccggtcg tttcgtacag
     9421 cgcccgcgcg tcctgaatgg ataggaccag catcgggccg gccagcaccg ccaaccggct
     9481 ttccggatcg cccggttcgc gcaccagacg tgtgaacaac accgatccca gtgcggcatc
     9541 ccggggcaca ctctccgccg gtatgtcata cagccgaccg tctcccagag atttcagact
     9601 tctgcgcgcc gctcccgcct gtgacgggag gatttccaca agatccaggt acgaatgttt
     9661 cagcggatcc agccagaccc gctcttcttc ggggatgtgt tccgtgatga cgtcgcgcag
     9721 ttgttcgatg agagtgagct gtccgtcttc cggataaaag tcggcataga gcaggagatc
     9781 cgccagctcg acctcctccc gcaacggcgt caagggcgac tggctcccca gttcgacata
     9841 gacctgcaac gcccgttcaa aagcgatacg gcgttgctgc gcgaatcccg gggacaggga
     9901 gagctgatcg agcctcgaaa tcagccgccc caggtcttta ttgacaggcg ccgaccgccc
     9961 gacgacccgt tcattcgcga gattcatgca tctcctccat gacgatggcc tcggcatcca
    10021 gccaatcctc caacgcaaac ccttcacggg atcctcgctc ccgccacaag tcatacgcct
    10081 tctgggaaat gcgctcccac atgccgtcgg gtaacgcact gggattgacg gcggtttgtt
    10141 ccttggctcg gggagaggga ggagcagctg cacgagattg ttccttacgc ttcatggagg
    10201 cctccttccg gtgaacctgt tcgattcatg aatttcccag ggggacgacc cgctcgtagt
    10261 ccgcgccaaa gttgacctgg agcacggtca ggactgggca aggtgcatga cgcaacatcg
    10321 cgccggcaat actgccgagc aggacatggg aaatgccccg acgcccatgc gtccccatga
    10381 tcatcaaatc gaatccctgc tgggtgacat gcgacacaat cgaatcggcc ggcagccccg
    10441 gcttcagcac atgatcggcc tggattccgt gggccgtcac gcaggcagat aacacgctca
    10501 accgcttctc taaataatcc cgttgctcct tccactcctt ggcgtggctc aaactgaaat
    10561 ccaggccgta ggcaaccggt tccatcgcat ggaggatggt gattgcggcc ccaagcggtt
    10621 tggcaaactg cacggcatac tccaaggcat ccagcgaaca ggtggagaga tccaccggca
    10681 ccacgatccg cttgattggc gccgccgcag acgaatcggc aacacccttg tctgccttga
    10741 ccgccaggac aggacaagga gagacccgca cgacgcgctc cgccgtgctg cccaccaaga
    10801 catgatccag ccccgtccgg ccatgcgtgc cgacgaccag gagatccgcg ccggtcgact
    10861 cggcgacggt ttgaagcgct tgactgggga ttcccacttc gatgcgcgtc gtgactgact
    10921 gactggccgc cttcgcgcgg gcctgaaccg cgcccaattg gcggttcgcc tcttcgcgca
    10981 agtggtccag gtacatcttg ttgaccgtat agtccggatc catccccgga tagagctcca
    11041 gcacggtcac gacgcagaga ttagccttcc aggctccggc caggctcaga gcatacccca
    11101 tggcccgatc ggcgcaggcc gagaagtcgg tggcgaacag catgtgcttg atcagtggga
    11161 ccatggctta tgccgcctcc acattcagga ggagcaattc ccctttcatg ttctgatgaa
    11221 tcgaacaacg aaattcgtgc cgtcccggcc gctccatcac gaaccggatg acggccgatt
    11281 ttttgccatc caggaacact ccgctgatcc cccggccata agagacaatg ccgccggatt
    11341 cgacccgtgt cggaaggcca tcgaacatcg tcgatccgaa atcgtggcgt tcctggtcct
    11401 cattcgtgat ggtgatcacc gtcgccaccc ccagccgcag cggcacctgc ttggtgacga
    11461 acgcaaagtc cttgatcgcc acatcgatcc gctgttccgc ctgagcgcca ccctgggaac
    11521 agagcgccag cacgaaacag attgccaacc agacccgccc tccgctgaga accgctgacc
    11581 tctgcttcag ccccatgacc atgcctcctt atgatgaact cttcccgctt cgcgctttcg
    11641 cccgcttcac cggcaagggt accgtcaaga caggacagcc ggcggtccgc accacttttt
    11701 ccgccgttgt gccgaagaaa atcttttcga ccccgcccac tgctcctcca taactgccca
    11761 tcacgactaa atcaacccct tccaccctcg cggtccttgc aatctcctcg aacgggcagc
    11821 cgtccgcgag cacccgcttg atcgatagcc ccttcgcctc atcccaggcc agtaactggc
    11881 gggcgttcaa ccgagcatga tgatgcagtt gctttttttg cttcgcggct tccgacgcgg
    11941 gggccaatcc cagccggttg agggcgtcca aactttttgt gtcgacgacg tggagcagga
    12001 ggacctccgc ctgataggaa cgcgcaaagg aaagcgcgat ccgataggcc tcctcagagc
    12061 atggcgagaa atcgaccgga acgagaattt tcgtgaacag acgttcgacc atccgacctc
    12121 tccacccttt ctgctgtatt acacatcagc aagcccaatg ccatcagctt ggctccgata
    12181 ccagcacaga atcatcagga ttcccctgca atcacggtat gccatgggcc gccccccgac
    12241 acagagacct gtgaggtggt gtcttgctac aggctccatc caccatctgt agcggaacgc
    12301 cacagattgc cgaacccgtc gcatttacga agaataaccg atctcatgcg tcgccgcttc
    12361 aggcggggat ctaagacgcc gccatactca ctgtacgaag cagtctgcga aaccgtgatg
    12421 gcattgctct tgctcgctcc agtcttggaa aggaatgcac catgtcgcgc acatcctggt
    12481 ggttgatcgg ggccttgctg ctggggacgg gcatcgcagt gtacctgatt ttcttctgtc
    12541 cggtggaatg ccattgaacc tcgcctgaag gacgtcgttc ggcacgtatg aggatggaga
    12601 gcatttctca gatcacgatc accggggatg gaatcgccct cgacggaatc ctcggacttc
    12661 cggggcagcc gaagggggtc attgcgtttg cccatggcag cggcagcggt cgcttcagcc
    12721 cccgcaatca gttcgtcgcc cgcgtcctgg agacaggcgg attcgccacc ctgctcctgg
    12781 atctgctgtc gcccgatgag gccgacgatc ggcggaagat tttcgacatc gacctcctgg
    12841 ctgaccgctt gctcctagca cagcactggc tgcagaccca tgcctcgacg cgaactcttc
    12901 gcacgggata tttcggggcc agcacaggag ccggagctgc cctccaagcg gccgcgcgcg
    12961 agcccgatgc ggtgggtgcc gtcgtctcgc gcggcgggcg ccccgatctc gccggtccgt
    13021 acctgagccg cgtcatcgcg ccgaccttgt tgctcgtggg tggcgaggat ggtccggtga
    13081 tcggcatgaa tgaggaggca ctcgggcagc tgacttgtca gaaacgattg atcattatcc
    13141 cgggggccac gcatctcttc gaagaaccgg gcacacttga gcaggtcgcc caagaggccc
    13201 tcaactggtt tcgtcggtat ctccatccgg caccgtacca accaaaggag ctcctgccat
    13261 gaacacgttg ctcgcagtcg atggatccga ccatgcgtat gaagccgtga gggcgctgaa
    13321 gtatctgcgc cgcgcggatc agctcacact tctgcacgtg gttgatgccc cgcgtccggc
    13381 ttaccctatg atggtgccgg aagtggcgca ggaactgtat gctcagttgg aacgcagcat
    13441 gaaagaggac ggcgaggaat tgttgacgcg gattcagtcg ctccttcccc ttcacagcgg
    13501 gccggtcacc aaactgctgc aggtgggatc accggcggag catatcgtgg ctgcggctca
    13561 atcctgccag gcggatctca tcgtcatggg ggcgagaggc ctgggcccgg tgaaggaacg
    13621 gctgctcggc agcgtctctc atcgcgtatt gagtatggct ccgtgcgcca aattcgttct
    13681 tcacggatca ttgcgccagt tgaagcacat cctcctcccg ttgcagggac cgtccgacgc
    13741 cgaggcggca ctccggtttc tcgccaaaca gccctttcag gaaccggtga atgtgagcgt
    13801 cctgaccgtc cttccgccca cacgtccccc atggccaata gacgataccg cggctgaaaa
    13861 attagaggcg cacgcgctgc gtcacgcccg cgacttcgtg gaggatgtgg cggcgaccct
    13921 tcgcacacag ggctatacaa cccgcagtgc gagtgtgctg ggttccccgc tcaccatgat
    13981 tctgcacgag gcggaaaaat tgggggcaga tctgattatg gtcggctcac gcgccagaca
    14041 gggcatcacc cgcttcgtcc tggggagcgt ctctcacgcc gtactccacc gggccccatg
    14101 ccaagtgctg gtgttcgagt gatagagtcg ccgccctcga tcgcgcggcg tttggtgaga
    14161 tcgtcgttgc cgtcgtatcg gtgtactgtg cgacttaatt ctagggtctc tccgacgact
    14221 tagggagtcc ggagttggag ggttaggtct tgcaatggtg aatcatgtgt gcgagcagct
    14281 caggatgctc gtgcgatcct gatggtcaac tacaatatcc tgcgtggcat tgccacgact
    14341 ggtcacatga tagacggcag cgggaaactc tatgcgcaac gaacgggcca tgggcgagac
    14401 gtgagcaact cacatgtatg agtgcaaaac cccttctggg gctggcatat gctctcctgg
    14461 tcatcattgg gagaccaagt ccttccatat cctttcgaat gctcccacac ttacttagat
    14521 ttcctcagga cggttccggc tccaggccct ggtgtattga gccactttac agactcaccg
    14581 ggacgaccct agtcgaaaat atctgttctc acccattccc tctttatgaa tgccgcgtaa
    14641 tcacaagtca cgtgtagcat cccatcttcc actttttccg gttttccata aacgatgagc
    14701 atattgttta aatccttagt gacattctcg tctttcaact tggacggaca aagtgttgtg
    14761 aacaccccct cccctcgcgg agaaaggaaa tatttttctt tttgaatgct atggtccagt
    14821 atccaatcgt aatagtgatg ctccacgaca attctcgtga agtatgcgct gtctttctgt
    14881 atcgaattca gctctgttat gaagcccggc catgccacca ggctagcctg atatcgttcg
    14941 acatcttttc tcgcatcatt cggaaagaca ccgaggtcgg ctgttgcaaa atatgacttt
    15001 tccgcctcgg agaaaccctt atacatttct gatctgggta atgggcagcc ggatagaacc
    15061 acggacatga gtacgatggc cggaataatg gcgggcagct ttatcgtcat tggtatctca
    15121 aactaatcca aaaggggtca ggtcttgcaa tcacacatgc ccggaggagc cgggtcgttg
    15181 ctatcgtttg tttcctgctc ggcttgcttc atgcagcgac tgatcgtcgc atagtgcacg
    15241 ccgcgatgca tggcaatttc gtctaaccga taaccatact ggcggtacgc caccgacacg
    15301 agccctgtcc cctcgcccgg tcggagttta gagaaagcct tgaccgaagt atggcttacc
    15361 actcctcgtc gctaagaacc ctcattcagc gttgatgcag gacattggtc gcctgacggg
    15421 ccggatcgtc actgtaggtc gtctgcgccc agttcgacag cgtgaggctc gtgacgaggc
    15481 ggttcgccag atc
//
LOCUS       DAOQPD010000093        15101 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_1998_length_15101_cov_23.637578, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000093 DAOQPD010000000
VERSION     DAOQPD010000093.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 15101)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 15101)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15101
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1998_length_15101_cov_23.637578"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            132..1814
                     /gene="ettA"
                     /locus_tag="PK063_16280"
     CDS             132..1814
                     /gene="ettA"
                     /locus_tag="PK063_16280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0045900 - negative regulation of
                     translational elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-dependent translational throttle protein
                     EttA"
                     /protein_id="HMZ98659.1"
                     /translation="MATNDKQVIFSLVGVGKVYPPKKQVLRDIYLGFYYGAKIGVLGL
                     NGSGKSSLLKIIAGVDPNYVGEITRSKGYSVGLLEQEPQLDPNKTVKEVVEEGKKELV
                     ALLHEYEAVSNSMGDASPDEMEKLIDKQAQLQEKIEAANGWELESELEIAMDALRCPP
                     ADQKVSVLSGGEKRRVALCRLMIQEPDILLLDEPTNHLDAESVQWLEQHLQQYKGTVI
                     AVTHDRYFLDNVAGWILELDRGHGIPFQGNYTSWLEQKQERLEKEEKAESKRKKTLEH
                     ELEWIRMSPKARQSKGKARLNRYEELVNQKQDQLAAELEIYIPPGPRLGDVVVEAKGI
                     SKAFGDNVLYENVEFSLPKGGIVGVIGPNGAGKTTMFRMIIGKEKPDSGTIRIGETVK
                     LGYVDQDRSLDPNKTVYEIISDGQDTVMLGKAEVNARGYCARFNFAGTDQQKKVKDLS
                     GGERNRVHLARMLKEGANLIILDEPTNDLDVNTLRALEEGLEGFAGCAVISSHDRWFL
                     DRIATHIMAFEGDSKVVWYEGNYSEYEADRKRRLGKEADQPHRIRYRKLTRN"
     gene            2283..3539
                     /locus_tag="PK063_16285"
     CDS             2283..3539
                     /locus_tag="PK063_16285"
                     /inference="COORDINATES: protein motif:HMM:NF013862.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HMZ98660.1"
                     /translation="MSMIWGRTLSRWLAVLALASASCTTIDAPRALPPDHRPAPTRAT
                     LQLGQKELADGRFVGLAFSGGGSRAAVFGAAVMKELERAGLLSQVDVLSAVSGGALPA
                     ASYALEGFGDFRFQDGFVEQIGRDIQGAVAGPWYAAPHNLVRYAFKDTIPAEPVIRAL
                     DDQLFRGATFADLNPSRPLLLLNSTDALTGDPLVIAEERFAPLGIPLAPFSIARAVYM
                     SAAYPGVLEPLKLTHGSTATNGASADPIIAYDGGAADNLGIRTLMQVVERALVNRPMT
                     DLFPQGCLVISIDATGRQRNETHTPLSAAAALLRGHRRNVLELAGIPASRQDVAQFGT
                     FRVGENGGGGSCRFWHVALRQLPDTDPLGDHVTHIKTNLGLSTEDQAALITAAARLVA
                     KGREELNGMAGWAGFLETKPALFSHP"
     gene            3536..4210
                     /locus_tag="PK063_16290"
     CDS             3536..4210
                     /locus_tag="PK063_16290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HMZ98661.1"
                     /translation="MTRPTDKHRIFITGATGYVGARLIPLLLERGHDVTALVRESSAG
                     KPVVGCRVVVGNPLDAESFAESVRGHDTLVQLVGVPKPSPWKGPQFRAIDGPSAMAAI
                     HAAASTGVQHYVYVSVAHPAPIMRDYIAVRRDCEEALRRAGLVATILRPWYILGPGHW
                     WPLALLPVYRMLERVPATREAAMRLGLVTIREMVAALLWSVEQPPVKTRVIDVPEIRR
                     LGRSEP"
     gene            4207..5085
                     /locus_tag="PK063_16295"
     CDS             4207..5085
                     /locus_tag="PK063_16295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HMZ98662.1"
                     /translation="MKRIALITGAAGLIGGYLVRSASRWVPDWEVVGVTRAEADFTDR
                     AQVEQLWNRHRPALVVHCAALSRIGLCEQDPVRARLTNVEATRLLADLARDVPFIFLS
                     TDQVFDGAKGQYVETDAVHPLNVYAQTKAEAEQVVLANPAHTVVRIALTAGMSPTRDR
                     SFVEDMVRTASKGVTLTLFTDEFRCPIPAGALVRALWELGMQRRPGLYHLGGHERLSR
                     WEIGELVAMRFPELRSSIQPGSVADYQGPPRPPDLSMCSEKIQALLSFPLPGFRQWLT
                     EHPSESGDPWDYPAAR"
     gene            complement(5098..5451)
                     /locus_tag="PK063_16300"
     CDS             complement(5098..5451)
                     /locus_tag="PK063_16300"
                     /inference="COORDINATES: protein motif:HMM:NF012264.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="c-type cytochrome"
                     /protein_id="HMZ98663.1"
                     /translation="MKGEHPVTMAIVMAVGTVLMQADVHGEAAGKADALAKGKQVFTR
                     HCAGCHGAEGKGDGYKLLGPDPANLTAPATRKQSDKALLTTIHEGKPNMPSWKGLLSE
                     RDITSVLAYIRSLPH"
     gene            5629..6429
                     /locus_tag="PK063_16305"
     CDS             5629..6429
                     /locus_tag="PK063_16305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1295 domain-containing protein"
                     /protein_id="HMZ98664.1"
                     /translation="MTATDPLSLLMTAWAASALLMVALWLLERRLHNLALADVGWCYG
                     LALVVLWYTTAVPGEPARRLLVCGMIVLYAARLGTHVLIDRLWDKSEDGRYRALRVQW
                     GEQGPLRRFWYFQLQAAAIVWFSLPPLIVMQNPHPPFHLMELLGVLLWMAAVTGEAMA
                     DWQLASFRRQPWNRDRVCREGLWYYSRHPNYFFEWLHWWSYVVMGLASPLGNWALTLI
                     GPLTMGWALLKVTGIPWTEAQTMTSRGEEYATYRRTTNAFFPWFPRRL"
     gene            complement(6670..6891)
                     /locus_tag="PK063_16310"
     CDS             complement(6670..6891)
                     /locus_tag="PK063_16310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98665.1"
                     /translation="MNTFLTWVILILLVSTSACGPDQASHMLETAQFEERQTNKAHAK
                     ELYEDIIRHYPDSPAAKTARTRLTELAKP"
     gene            complement(6989..7300)
                     /locus_tag="PK063_16315"
     CDS             complement(6989..7300)
                     /locus_tag="PK063_16315"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98666.1"
                     /translation="MITPPQTPRQRIMTLLTGTLLSSHQLAQLVGMPERQVEDHLTHI
                     VKTLARDTSRTFLLEPSHCQDCTYTFRDRTRLTRPSRCPRCRSEAITSPRYGIREEAG
                     S"
     gene            7415..8878
                     /locus_tag="PK063_16320"
     CDS             7415..8878
                     /locus_tag="PK063_16320"
                     /inference="COORDINATES: protein motif:HMM:NF039907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HMZ98667.1"
                     /translation="MSGSQWDELAELALSRVSSAGVEYADIRLLDTTTRTISGEDRRI
                     AHIRESTDRGFGIRVLHRGAWGFAASSIISLEEIPRVADLAVEIAKGSASLAITKVHL
                     APEPVHRDRIVTPSRLDPFAVPLEEQTALLLSTMDIIQRHPGVVRSHASLWAQRDRKL
                     FVSTEGSHLEFDLLAMQGDCTATAVHNGRFASRSFNTPHLRTGYELVRDADWVREGAR
                     IAEQAVEKVRAPAIDAGRYDLVLDPEHLSLTMHESCGHPSELDRALGYEANYAGTSFL
                     TPDKRGTYRYGSADVNLVADNTEPGTLAATGYDDDGVSCQKWDIVREGIFVGYCTNRE
                     VAPRIKEERSRGSNRADSWGSVPMVRIANIGLEAGTSTLDDLLADVKRGIYIEGHGSY
                     SIDQRRYNFQFGGDAFWLIENGRRTHMVRDVIYHGITPEFWGRCDGVADATHRRRYGF
                     ITCGKGQPGQSGWMTHAASHARFRRVDVISGHTKADA"
     gene            8875..10221
                     /locus_tag="PK063_16325"
     CDS             8875..10221
                     /locus_tag="PK063_16325"
                     /inference="COORDINATES: protein motif:HMM:NF039907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallopeptidase TldD-related protein"
                     /protein_id="HMZ98668.1"
                     /translation="MTSSITSSWSKLTSRQEFEFLADLVMSHSTGDHTFFSLRDSHGG
                     TTRFANNQIIQNVNLRRGHLSVTVAFGRQHGTASTTDFTAGAVREALKQAESLARLSP
                     DDPEYLPPVGAQSYLSLPTSRPETTAAGPARRLDYAREAIGQCKMENLNAAGTVSSST
                     TTVGLAAETGLRAYEERTEGRFSLTVQAGDATGWSAAAHRSIDRLHVQERTLAAIIKA
                     KRGADEPQELPPGRYTVILEPAAVAGLLSWMIWMLDAKSFYKGTSPFSGKLGSRIIDR
                     RLSLVNQPAHADLLGNSFTHEGLPVIESGWIESGVLTQLLHDRYTAREHQIEPLTTLE
                     SPHLSGERPIGTRVDDLIRTTQRGILVTNFWYIRPVNPSDLTLTGMTRDGTFLIENGE
                     ITSAVRNFRFHESPLRAFNQVETYTAPAEAVTSETGKALVPAMRIHDFHFSSVTKF"
     gene            10374..11081
                     /locus_tag="PK063_16330"
     CDS             10374..11081
                     /locus_tag="PK063_16330"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98669.1"
                     /translation="MTRKQQRLAEKPIHLLTLAPDKGEKGAVNPFAPSPLRAAIGKVF
                     VKLEDMTERFEDWCQYGNSEERTEQPLGQRVSNWLGAPVARHIEHQVQAEHGLVPARR
                     WDGAVGDLIFRLRDRAGFVQRALTAQARELKDWVIQHTQSTQAELHDLREQVATQQVQ
                     MEDLSAQLHDLRALVKSQQQVLMYMGKDMEMAPPAELELSLVSPRSIPYRERDKKSSR
                     DRRDTSNEASQIPYLNA"
     gene            11506..13140
                     /locus_tag="PK063_16335"
     CDS             11506..13140
                     /locus_tag="PK063_16335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98670.1"
                     /translation="MKNARYVRGVVYGLVIAGLALPVSDGIARSEVPLFENLGVLQHK
                     ITTHSDLAQKYFDQGLRLVYAFNHEEALAAFTEASRLDPDAPMPYWGVALSLGPNINA
                     GMDSKAESRAVEAVQKATARLAHATPTERAYVEALAARYSVKKAATRKGKDEAYAKAM
                     RRLAHEYPEDADAATIFAEALMVLRPWDYWRADGRPQPGTEEIVTTLEAVLQHQPDHP
                     GACHYYIHAVEASPDPQRGLPCAMRLPSLMPGAGHLVHMPAHIYMRVGRYRDASERNA
                     KAATVDHEYLLQHPLEGNYASGYYAHNLHFLNASLVMEGRSAEALQAARDLLSKISVN
                     EIVKEPSLEWYAPTVLLTMARFGQWGELIRQPPPPKELRYTTGLWHYVRGLAFAATTR
                     FGSAEGELSNLRKSLKGLARAKTAEGKISRTLLKIAERVLAGEIAARKGDFDAGIQAL
                     REALQLEATVPYSEPPFWFQPVRHNLGAVLLLAGRPGDAESVYREDLRLNPENGWALH
                     GLVHSLQAQRKETAQESARLHTAWAQADVPLTGSRF"
     assembly_gap    13238..13337
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            13352..14173
                     /locus_tag="PK063_16340"
     CDS             13352..14173
                     /locus_tag="PK063_16340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HMZ98671.1"
                     /translation="MLKTDYVFQATEEARELQRLQMLERIFDAGTQRRMLATGLTTGW
                     HCLEVGAGAGSIVRWLEQRVGPSGKVVALDTNPRFLRGSSTSTIDILQGDICDTDLPL
                     AMFDLVHARYVMIHIADYQKAFERMLRCVKPGGWVVIEEPDFEAARAVTASDDARTSF
                     TRVTAAIERMFTSLGMDYALGAKLPALFQRQDLSHLTVEHEGHLSAGGGATAQLMKLS
                     AEQLREKYVATGLVTESDIEQYCRLADDPDSWAIYYATVAVTGWWQPQCGGRTQG"
     gene            14176..14706
                     /locus_tag="PK063_16345"
     CDS             14176..14706
                     /locus_tag="PK063_16345"
                     /inference="COORDINATES: protein motif:HMM:NF037785.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98672.1"
                     /translation="MRYIVGVMGPAKARKKDVDNARVLGELIARREWVVLTGGRDVGV
                     MDAACQGAKKVPGSLTIGVLPSARERVSKYVDLAIITEMGNARNNVNVMSSNVVVVCG
                     LLGAGTVSEVALALKAGKPVILVGATPTEEKFFKKLGGRLIASVDSPEEAITLMMKQF
                     EQQQPDLVQGARSWGV"
BASE COUNT         2892 a         4333 c         4741 g         3035 t
ORIGIN      
        1 gatcttcgct gaatccgtgc gtctggaatc atgcccggag ctccctcgcg cggttgtgaa
       61 tactgccgcg ctttgttatg gtcatcgatt gcacgatcga acagacggtt cacactctac
      121 tgaggatggc tatggcgacg aacgataagc aagttatttt ttcactggtc ggagtgggca
      181 aggtctatcc gccaaagaaa caagtcctgc gcgatatcta cctgggtttc tattacggcg
      241 ccaagatcgg cgtcctcgga ttgaacggtt ccggcaaaag ctcgctgttg aaaatcatcg
      301 ccggggtgga tccgaattat gtgggcgaga tcacacgctc gaagggctat agcgtcggtt
      361 tgctcgaaca ggagccgcag ctcgacccga acaaaaccgt caaggaagtc gtggaggaag
      421 gcaagaaaga actcgtcgcc ttgttgcacg aatatgaagc ggtcagcaac agcatggggg
      481 acgcgagccc ggatgagatg gaaaagctca tcgacaagca ggcgcaactg caagagaaga
      541 tcgaggcggc gaatggatgg gaactcgaaa gcgagctgga aatcgccatg gacgccctgc
      601 gttgtccgcc tgccgatcaa aaagtgagcg tcctctccgg aggcgaaaag cggcgggtgg
      661 ccctgtgccg cctcatgatc caggagccgg atattctgtt actcgatgag ccgaccaacc
      721 atctcgatgc cgaatcggtg caatggttgg agcagcatct gcagcaatac aaaggcaccg
      781 tcatcgcagt gacgcacgat cggtactttc tcgacaacgt ggcgggctgg attctggaat
      841 tggaccgcgg gcacggcatt ccgtttcagg gcaactacac gtcttggctg gagcagaaac
      901 aggagcggct ggagaaggaa gagaaggctg aatcgaaacg caagaagacg ctggagcacg
      961 agttggaatg gatccggatg tcaccgaaag cccgtcaatc aaagggtaag gcgcgcctca
     1021 atcgttatga agaactggtc aatcaaaagc aggatcagct ggcggccgaa ctggagattt
     1081 atattccgcc gggaccgcgc ctgggcgacg tcgtggtgga ggccaagggg atcagcaagg
     1141 cgttcggcga caatgtgttg tatgagaacg tggaattcag cctgccgaaa ggtggcattg
     1201 tcggcgtgat cggcccgaac ggcgccggca agacgaccat gttccgcatg atcatcggca
     1261 aggaaaaacc ggacagcggc accattcgca tcggcgagac ggtgaagctg ggttacgtgg
     1321 accaggaccg atcgctggat cccaacaaaa ccgtctacga aattatttcg gacgggcagg
     1381 acacggtgat gctagggaag gccgaggtca atgcccgcgg ctactgcgcc cgcttcaact
     1441 tcgccgggac cgaccagcag aaaaaagtga aggacctctc gggtggagag cgcaatcgtg
     1501 tgcacctggc tcgcatgctg aaagagggcg cgaacctgat catcctcgac gagccgacca
     1561 acgacctcga cgtgaacacg cttcgcgctc tggaagaggg attggaaggg tttgccggtt
     1621 gcgccgtcat cagcagccac gaccgctggt tcctggaccg catcgccacg catatcatgg
     1681 ccttcgaagg cgacagcaaa gtggtctggt acgagggcaa ctatagcgag tacgaagccg
     1741 atcggaagcg ccggctcggc aaagaagccg accagccgca tcggattcgg taccgcaagc
     1801 tgaccaggaa ctagcccgca tgattcatga gcacttctgc tgcaatcgcc aactcactgc
     1861 tacgacgagc cttcggccag cgggctcgcc cctcggaccc tcaacgtact gcacgagtac
     1921 gcttcgggtc ctcccgggct ccgcgcgccg gtctcgccac gtgactcggc gatttcgcga
     1981 cgaaccgtca tgaatcatgc gggctagccg gctgttgaaa aagggctgcc ggcggcgttc
     2041 tcgcggcgcg aagaggctcc acgtaccgca aagggtacgc atcgcctcta cgctggctgc
     2101 ggccttgccg gacagccttt ttgaacaacc tgccacggcc actgcgcacg tctctgagtc
     2161 tttgagagtc acatagttgc tgtaggcctg tatggtgtca gcatcctgtt agcgtccgcc
     2221 tcaacgccag gactccttac tagaagcaca tccattttcc gcattcggcc gtagattcat
     2281 ccatgagcat gatatgggga cgtactctaa gccgttggtt ggcggtgctt gccctggctt
     2341 ccgcctcctg cacgaccatt gatgctcccc gggccctccc gcctgaccat cgtcctgcac
     2401 ccacaagggc cacgctgcaa ttggggcaga aggaattggc ggatggacgg tttgtcggac
     2461 tggcgttctc cggcggaggc agtcgcgcgg ccgtcttcgg ggcggccgtc atgaaggagc
     2521 tggagcgggc cggcctgtta tcgcaggtcg atgtgctttc ggcggtctcc ggcggcgcgc
     2581 tgcccgctgc atcctatgca ttggaagggt tcggagactt tcggttccaa gacgggtttg
     2641 tggagcagat cgggcgcgat attcaaggcg cagtggcggg gccctggtat gcggctcccc
     2701 acaatctggt ccggtacgcc ttcaaggaca cgatccccgc cgaaccggtg atccgtgctc
     2761 tggacgacca actgtttcgc ggtgccacgt tcgcggacct caatccctcc cgacccctct
     2821 tgctcttgaa ctccacggat gccctgaccg gcgatcccct ggtgattgcg gaggaacgat
     2881 ttgcaccgtt gggcatcccc ttggcgccgt tcagcattgc ccgggccgtg tatatgtctg
     2941 cggcctaccc tggcgtgctg gagcccctga agcttaccca tggaagtacc gcaacgaacg
     3001 gcgcgtccgc cgatcccatc atcgcctatg atgggggcgc ggctgacaat ttggggattc
     3061 ggactctcat gcaggtcgtc gagcgagcgt tagtcaaccg tcccatgacg gatctctttc
     3121 cgcaaggttg tctcgtcatc tccatcgatg cgacgggccg ccagaggaat gagacgcaca
     3181 cgccgctctc cgccgccgcg gccctcttgc gagggcatcg tcgcaatgtg ttggagctgg
     3241 ccggcattcc tgcatcccgg caggatgtgg cccagttcgg cacctttcga gtgggcgaga
     3301 acggtggcgg aggatcctgc cgcttctggc atgtcgcact gcgccagttg ccggacaccg
     3361 atccattggg agaccacgtt acgcatatca aaacgaacct cgggttatcg actgaggatc
     3421 aggctgcgtt gattaccgcg gcagctcgcc tcgtcgcgaa gggccgcgag gagctgaatg
     3481 gaatggccgg gtgggccggt ttcctggaaa ccaagccggc gctgttctcg catccatgac
     3541 taggccgacg gacaagcatc gcattttcat cacgggcgcc accggatacg tcggggcgcg
     3601 gctcattccg ttgctgctcg agcgagggca tgacgtgacg gcgttggttc gcgagtcctc
     3661 tgcaggaaag cctgtcgtcg ggtgccgggt tgtggtcggc aatccactgg atgcggagtc
     3721 cttcgcggaa tctgtgcggg gacacgatac actcgtgcag ctggtgggcg tacccaaacc
     3781 atcaccctgg aaggggccgc agtttcgcgc gattgatggg ccctcggcca tggccgcaat
     3841 tcacgccgcc gcttcgacgg gcgtgcagca ctatgtctac gtcagcgtgg cccatccggc
     3901 gcccatcatg cgtgactaca tcgccgtacg tcgtgactgt gaagaggctc tcaggcgagc
     3961 cggattggtc gccacgattc tgaggccctg gtacattctc ggtcccggac attggtggcc
     4021 attggcgctg ttgccggtct atcgtatgct ggaacgagtg cccgcgacga gggaggccgc
     4081 catgcggttg ggtttggtga cgattcgaga gatggtcgcg gccctgctgt ggtctgtcga
     4141 gcagcctccg gtgaagacca gggtcatcga cgtgccggag atccggcgcc tggggcggag
     4201 cgaaccatga aacggatcgc actcatcacc ggtgcagcgg gtttgattgg tggctacctc
     4261 gtcaggagtg cctcgcgctg ggtgcctgat tgggaggtgg taggcgtgac gagggccgag
     4321 gccgatttca cggatcgagc ccaggtggaa cagctttgga atcgccaccg cccggctctc
     4381 gtcgtccatt gcgcggcctt gagccgcatc ggtctctgcg aacaggatcc cgtacgggcc
     4441 aggttgacca atgtcgaggc cacgcggctc ctggccgacc tcgcgcgaga cgtgcccttc
     4501 atctttcttt ccaccgacca agtgtttgat ggcgcgaagg ggcagtatgt cgaaaccgat
     4561 gcggtccatc cgttaaacgt ctacgcacag acgaaggccg aggcggagca ggtcgtcctc
     4621 gccaatccgg cccatacagt cgtgcgtatt gcgctgaccg cgggaatgtc accgacgcgc
     4681 gaccggagtt tcgtcgagga catggtgcgc acggcatcga agggggtgac actcacactg
     4741 tttacagacg agtttcgctg tccgatcccg gcgggtgccc tggtgcgggc gctctgggag
     4801 ctcggcatgc agcgccggcc gggtctgtat catctgggtg gccatgagcg gctctctagg
     4861 tgggagatcg gagagctggt ggcgatgcga ttcccggaat tgcggtcttc gatccagccc
     4921 ggttcggtgg cagattatca ggggccgccg cgtccgccgg atctctcgat gtgcagtgag
     4981 aagatccagg cactgctatc gttccctctg ccgggatttc gccagtggct gacggagcat
     5041 ccgtcggaga gtggcgatcc gtgggattat cccgctgccc gctagattga ggcgaaatca
     5101 gtgcggcagc gaacggatgt aggccagcac gctcgtgatg tcgcgctcgg agagaagccc
     5161 tttccacgaa ggcatgttcg gtttgccttc gtgaatggtg gtgagcaacg ccttgtctga
     5221 ttgcttcctg gtcgcgggag cggtcagatt ggccggatcc gggccgagta gtttgtaccc
     5281 gtcgcctttc ccctctgcac catgacaccc ggcgcaatgc ctcgtgaaca cctgtttccc
     5341 ctttgccagg gcatcggcct ttcctgccgc ttcaccgtgc acgtccgcct gcatcaagac
     5401 tgtcccgacg gccatgacga tggccatcgt aacgggatgt tcgcccttca tctctgttcc
     5461 tcctgtgtat caagcaccct tgctctgata tgagcaatca tacgcccgct gcggtggcaa
     5521 tgccatgcga tctcctcctc cgtgtgtcgc gatgtccgtc gtagtacaat catctgaaca
     5581 cgaaccacac gtgatgtatc tttgcatttc acgtcgatca ctgatcgcat gacggcgaca
     5641 gaccccctct cccttctcat gaccgcttgg gccgcttcag cgctcttgat ggttgcgctc
     5701 tggttgctcg agcgccgcct gcacaatctt gctctcgccg atgtgggctg gtgttacggg
     5761 ttggccttgg tcgtgctgtg gtacaccact gctgttcctg gcgaaccggc gaggcgtctg
     5821 ttggtgtgcg ggatgatcgt gctctacgcc gcacgcctcg gcacgcatgt cctcatcgat
     5881 cgactgtggg acaaatcaga agacggccgc taccgcgccc tgcgtgtgca atggggcgag
     5941 cagggtccgc tacgccggtt ctggtatttt cagttgcagg ccgcggccat cgtctggttc
     6001 tcgcttccgc cgctgatcgt catgcagaat cctcatccgc cgtttcatct catggagcta
     6061 ctcggggtcc ttctctggat ggctgccgtg acaggggagg ccatggccga ttggcagttg
     6121 gcatcctttc ggcgtcagcc atggaaccgg gaccgtgtgt gccgggaagg gctgtggtac
     6181 tactcgcgac acccaaatta cttttttgaa tggctgcatt ggtggagcta cgtggtgatg
     6241 ggactggcga gtccgctggg caactgggcg ttgacgctga ttggcccgct gacgatgggc
     6301 tgggcactcc tgaaagtcac cggcattccc tggactgaag cacagaccat gacgagccgg
     6361 ggtgaggagt atgccaccta tcgccgcacc acgaatgcgt tctttccctg gttcccccgc
     6421 cggctgtaac ccggactatt catgaatgcc tgctccggcg tccgatcctg tcgcccggcg
     6481 aggctgttct cgctcggcct cctcgacgga ctgccagtac gcctgcgtcg gcctcacgtg
     6541 cgagcagcct cggcgggttt cggtctcgaa cacctcgcga cggcattcat gaataatccg
     6601 ggttaacaag aagccaaaaa cgtccgccag cggcgttcgc gaccatcact gcagcgcagc
     6661 tggctgttgt tatggtttgg cgagttccgt cagccgtgtc cgtgcggtct tggcggcggg
     6721 actgtccgga tagtgacgga tgatgtcttc gtacagttcc ttcgcgtggg ccttgttggt
     6781 ttgtcgctct tcaaactggg cggtctcgag catgtgcgac gcctgatccg gcccgcaggc
     6841 cgatgtgctc acgagcagga tgagaatgac ccacgtcagg aatgtattca tgcgacggtc
     6901 ctttcatgta tcggtcgcgt ggcgtgctca ttgccggtct gccacgctcg cagggtttcc
     6961 agtggtctgg aggagacagg ccgcatcatc atgaaccggc ctcttcccgg atgccatatc
     7021 gtggagaggt aatggcttcg ctgcggcagc ggggacaccg gcttggtcgc gtgagcctgg
     7081 ttcgatcgcg gaaggtgtac gtacaatcct gacagtgcga cggttccaac agaaatgttc
     7141 gtgaagtgtc gcgtgcgagc gtcttgacga tgtgggtcag gtgatcttcc acctggcgct
     7201 ccggcatgcc gacaagttgc gccaactgat gagaagataa caacgtaccg gtcaacagcg
     7261 tcatgattcg ctgccggggt gtctgcggtg gagtgatcat gccatcttga ttgtaggtga
     7321 accgcctgtc gatgaaaagg caggcacgag cgaccgcgat cttgttatac tacgcgaaac
     7381 tgcctgtgca ttcggcgcag agaaagacgc cgctatgagt ggatcgcagt gggacgagct
     7441 ggccgaattg gccttgtctc gtgtgtcttc ggccggagtc gagtatgcgg atatccgcct
     7501 gcttgatacg acgacgcgga ccatcagcgg cgaagaccgc cgcatcgccc atatccgcga
     7561 gtccaccgat cgagggttcg gtatccgcgt gctgcaccgc ggcgcctggg gttttgccgc
     7621 cagctccatc atttcactcg aagaaattcc tcgtgtcgcc gatctggccg tcgaaattgc
     7681 caaaggttcg gcctctctcg cgatcactaa agtccacctg gcccccgagc cggtgcatcg
     7741 agaccgcatt gttactccct cccgccttga tcccttcgcg gttccattgg aagaacaaac
     7801 cgcactgctt ctgagtacga tggacatcat ccagcggcat cccggtgtgg tgaggagtca
     7861 cgccagccta tgggctcaac gcgatcgcaa actgttcgtc tccactgaag gttcgcatct
     7921 cgagtttgac ctgctggcga tgcagggcga ttgtacggca acggccgtcc ataacggacg
     7981 gtttgcgagc cggtcgttca acactcccca tctgcgtacg ggctatgagc ttgtgcgcga
     8041 cgccgactgg gtgcgtgaag gggcgcgcat cgcggaacag gccgtggaga aagtgcgggc
     8101 tccggcaatc gatgcgggac ggtacgacct ggtgctggat cccgagcacc tgtccttgac
     8161 gatgcatgag tcctgcggac atccgagcga attggatcgc gccctcgggt atgaagccaa
     8221 ttatgccgga accagttttc tgacacccga caaacgcggc acgtaccggt atggctcagc
     8281 ggacgtgaac ctcgtggcgg acaacaccga accggggacg ctggcggcga ccgggtatga
     8341 cgatgacggc gtcagctgcc agaagtggga cattgtccga gagggcattt tcgtcgggta
     8401 ctgcacaaat cgagaggtgg caccacgaat caaggaagag cggtcacgcg gatcgaaccg
     8461 cgccgatagc tggggatcgg ttcccatggt ccggattgcg aacatcggtc ttgaagcggg
     8521 aacctccacg ttggatgacc tgctggccga cgtgaagcgg ggcatttata tcgaaggcca
     8581 tgggtcctat agtatcgacc agcggcggta taattttcag ttcggtggcg acgcgttctg
     8641 gctgatcgag aatggccggc ggacgcacat ggtgcgggat gtcatctatc acggcatcac
     8701 cccggaattc tggggccgct gcgacggcgt cgccgatgcc actcatcgtc gccggtatgg
     8761 cttcatcacg tgcggtaaag ggcagcccgg ccaatcgggc tggatgactc acgctgcatc
     8821 ccacgcccgc ttccggcgcg tggatgtgat cagcggacac acgaaggcgg acgcatgacg
     8881 tcatcgatca cgtcctcatg gtcgaaactg acgagtcgcc aggagtttga gtttctggcg
     8941 gacctcgtga tgagtcactc tacgggcgat cacaccttct tctcattgcg cgatagccac
     9001 ggcggtacca cgcggttcgc caacaaccag atcattcaga acgtcaatct tcggcggggc
     9061 cacctctccg tcaccgtggc cttcgggcgc cagcatggca ccgccagcac cacggatttt
     9121 accgccgggg cagttcgcga agccctgaag caggccgaat cgctcgcgcg gctctccccc
     9181 gacgatccgg aataccttcc gccggtcggc gcgcaaagct atttgtccct gcccacgtcc
     9241 cgtccggaaa cgactgccgc cggcccggcc cgacggctcg actatgcgcg cgaagcgatc
     9301 gggcaatgca aaatggaaaa tctcaacgcc gccggcaccg tgtcgtccag cacgacgact
     9361 gtgggattgg ctgctgagac gggattgcgc gcctatgaag aacgcaccga agggcggttc
     9421 agcctgaccg tgcaggccgg cgatgccacc ggatggtcgg ctgcggccca tcgttccatc
     9481 gaccgcctgc acgtgcagga gcgcaccctg gcagccatta tcaaggccaa gcgcggggcg
     9541 gacgagccac aggagctgcc gccgggccgg tacacggtca tcctggaacc ggctgccgtg
     9601 gccggactcc tcagctggat gatctggatg ttggatgcca agtcttttta taaggggacc
     9661 agcccattca gcggaaagtt gggctcacga atcatcgatc gccggctctc gctggtgaat
     9721 caaccggccc atgcggacct cctgggaaac agctttacgc acgaagggtt gccggtgatc
     9781 gagtccggct ggatcgagtc gggtgtcctg acccaacttc tgcatgatcg gtatacggct
     9841 cgcgagcatc agatcgaacc cctcacgaca ttggagtcgc cccacttatc aggcgaacgt
     9901 cctatcggca ccagggtgga cgacctcatt cgcacgacgc aacgaggcat cctcgtgacg
     9961 aacttctggt acatccgtcc cgtcaatccg tccgacctga cgctgaccgg catgaccagg
    10021 gatggcacat tcctgataga aaacggggag atcacgtctg ccgtccgaaa ctttcgcttt
    10081 cacgaaagcc cgctgcgcgc ctttaatcaa gtagagacct ataccgcgcc ggctgaggcc
    10141 gtgacgtccg aaacaggaaa agcgctggtg cctgccatgc gcatccacga ttttcacttc
    10201 tcgagcgtga ccaagtttta ggctggcctg tcgcccagac cctgtctcgg tccgggcgcg
    10261 tcagtcggac cgggggagaa aaaaacaccc actcgccatt gactcggact atcggaaaga
    10321 gtaatgaatt gggaaaagtt tgccgataag gctcggaagg cttcgatcgt cctatgacgc
    10381 ggaaacagca gcgtttggcg gaaaaaccca ttcatcttct cacgctcgcc ccggataagg
    10441 gtgagaaggg ggcggtgaat ccgtttgcgc cttccccatt gcgtgcggca atcggcaagg
    10501 tgttcgtcaa gctggaagat atgacggagc ggttcgaaga ctggtgccag tacggcaact
    10561 ccgaagagcg gacggaacag ccgttggggc agcgggtgtc gaactggctg ggcgctcctg
    10621 tcgcgcggca catcgagcat caggttcaag cggaacatgg gctggtgccg gcgcgccggt
    10681 gggatggtgc cgttggtgac ctcattttcc ggttgcgtga tcgtgcgggg tttgtccagc
    10741 gtgccttaac cgcccaagcc cgtgagctca aggactgggt catccagcat actcaatcca
    10801 ctcaggcgga actccatgat ttacgcgagc aggtcgccac gcaacaggtg cagatggaag
    10861 atctgtcggc gcagcttcat gacttgcgtg ccctggtgaa gtcccagcag caggtcttga
    10921 tgtacatggg caaggacatg gagatggccc cgcccgcaga gctggagctg tccctggtgt
    10981 ctccccgatc gattccctat cgcgaacggg acaagaaatc atcgcgtgat cgacgggaca
    11041 cgtccaacga agcttcccag attccctacc tcaacgccta gcaggatgcg gaaaaagtcc
    11101 gccagcggcg ttctcgcgtc actccgagac tcaccgtacc gcgggagtac gattcgcctc
    11161 ttcgctcgct gcggccttgc tggacgatcc ttttgcgcat cctgctagat ttctggggtc
    11221 gagcaggacg ctgaaaacaa ccgtcagctt tgttctcaca tcgttcggac cctgaacgtc
    11281 ctccagacgg tacgcctccg cgccttcact cgctgcggcc tcgctggtcc atgattttga
    11341 tcgtcccgca tcaatacgta ttcagccctt ctttcttctc agcctgctcc gactagcaac
    11401 ttctcgtcgg gactgctaat ttgtgccctt ctgtgcgcgg cggagtcgtc gcagtgtgac
    11461 ggcattgccc gtctcgcata cgaaaaacga gcaggagcgg ggaacatgaa aaacgcgcgg
    11521 tatgtgagag gggtggtcta cggcttggtg atcgcaggtc tggcgctgcc tgtgtccgat
    11581 ggaattgccc ggtcagaggt gccgctgttc gagaatctcg gtgtgctgca gcataagatc
    11641 actacccact cggaccttgc ccagaagtat ttcgaccagg gattgaggct ggtctatgcc
    11701 ttcaaccatg aggaggctct agcggccttc accgaggcgt cccgtctcga tcctgatgcg
    11761 cccatgccct attggggcgt ggcgctgagc ctggggccga atatcaatgc ggggatggat
    11821 tccaaggcag aatcgcgagc cgtagaggcc gtacagaaag ccacggcacg gctggcgcat
    11881 gcgactccca cagagcgggc gtatgtggag gcccttgccg cgcggtattc ggtcaagaaa
    11941 gctgcgactc gcaagggcaa ggacgaagcc tatgccaagg cgatgcgacg cctggcccat
    12001 gagtatccgg aggacgcgga tgcagcgacc atatttgctg aggccttgat ggtgctccgc
    12061 ccctgggact attggcgagc cgatggccgc ccgcagcccg ggaccgagga aattgtgacg
    12121 accttggagg ccgtgctgca gcatcagccg gatcaccccg gtgcttgtca ctattacatt
    12181 catgcggtgg aagcgtctcc cgaccctcaa cgcgggctgc cttgcgccat gcgtctgccg
    12241 tcgctcatgc cgggcgccgg gcatctggtg cacatgccgg cgcacattta catgcgggtg
    12301 gggcgctatc gggacgcctc agaacggaat gccaaggctg cgaccgtgga tcatgagtat
    12361 ttgcttcagc acccccttga gggcaactac gcatcgggat actatgcgca caaccttcac
    12421 ttcttgaatg cgtcattagt gatggaaggg cgaagcgcgg aagctctgca ggcggcacgg
    12481 gatctcctga gcaagatttc ggtcaacgaa atcgtgaaag agccttcgct ggaatggtat
    12541 gcgcccacgg tcctgcttac gatggcccgg tttggtcagt ggggtgagtt gatcaggcaa
    12601 ccgccgcccc caaaagaact gcggtatacg accggtctct ggcattacgt gcgcggtctg
    12661 gcctttgcgg cgacgacgcg gttcggcagc gcggagggtg agctctcgaa tcttcgaaag
    12721 tcattgaagg gattggccag ggcgaagacg gctgaaggca agatcagccg cacgctgcta
    12781 aagattgccg agcgggtgct ggcgggagaa atcgcggcac ggaaggggga tttcgacgcc
    12841 gggatccagg ccttgcgcga ggccctccag ttggaagcca cggtgccgta tagcgaacca
    12901 ccattctggt ttcagccggt tcgtcacaac ctgggggcgg tactgctctt ggcgggacgt
    12961 cctggcgatg cggaatctgt gtatcgcgag gatttgcgcc tcaatcccga gaacggctgg
    13021 gctttgcatg gattagtgca tagtctgcag gctcagcgga aagagactgc gcaggagagt
    13081 gcgcggttgc atacggcctg ggcccaggcc gacgtcccac tgaccgggtc tcgcttctag
    13141 gatcagctga cgcgcggcca cgagctggcg tcatggtgcc gaataaagga taagacatgt
    13201 tgaagacgga ttatgtgttt caggccaccg aggaagcnnn nnnnnnnnnn nnnnnnnnnn
    13261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13321 nnnnnnnnnn nnnnnnnata aaggataaga catgttgaag acggattatg tgtttcaggc
    13381 caccgaggaa gctcgtgaat tgcagcgtct gcagatgttg gagcgtatct tcgatgccgg
    13441 gacgcaacgc cgtatgttgg cgaccggcct gacgaccggc tggcactgtc tggaagttgg
    13501 tgcgggtgcc ggttccattg tgcgttggtt ggaacaacgt gtcgggcctt cgggcaaagt
    13561 ggtcgcgctc gataccaatc cgcgcttttt gcgtggcagc agcacctcga ccatcgacat
    13621 cctccaagga gatatctgcg acacggatct cccgctcgcc atgtttgatc tggtgcatgc
    13681 gcggtacgtc atgattcata tcgccgacta tcagaaggcg tttgagcgga tgttgcgctg
    13741 tgtcaaaccg ggcgggtggg tcgtcatcga agagccagat tttgaggcgg ctcgcgccgt
    13801 caccgcgtcg gatgacgcca gaacctcttt cacgcgcgtc accgctgcaa tcgagcgtat
    13861 gttcacgtcg ctcgggatgg actatgcgct gggggcgaag ttgccggcct tgtttcaacg
    13921 acaggatctg agtcacctaa cggtggagca tgaaggacat ctgtcagcgg gcggtggagc
    13981 gaccgcgcag ctgatgaaac tctccgccga acaattgcgg gagaaatatg tggccaccgg
    14041 cctggtaacg gagtcggaca tcgagcagta ttgccggctc gccgacgatc cggattcctg
    14101 ggccatttat tatgcgacag tggccgtgac tggctggtgg cagccgcaat gcggcgggag
    14161 aacgcaggga taggcatgcg atacattgtc ggagtaatgg ggccggccaa ggccaggaaa
    14221 aaggatgttg ataatgcccg ggtcctgggt gaactgatcg cgcgccggga atgggtcgtg
    14281 ttgacgggtg gccgcgatgt cggtgtcatg gacgcggcct gtcagggcgc caagaaagtc
    14341 cccggtagtt tgacgatcgg tgtgttgccg tcagcgcgcg agcgtgtgtc gaagtatgtc
    14401 gatctggcga ttattacgga gatgggcaat gcgcgcaata acgtcaacgt catgtccagc
    14461 aacgtggtcg tcgtgtgcgg gctgctgggc gcagggacgg tgtcggaagt tgccttggcg
    14521 ttaaaggcgg ggaagccggt cattctggtc ggggccacgc cgaccgaaga gaaattcttc
    14581 aaaaagctgg gcggacgcct gatcgcctcg gtggatagtc cggaagaagc gatcaccctg
    14641 atgatgaaac agtttgagca gcagcagccg gatctggtcc agggcgcacg ctcctggggt
    14701 gtttagcagg tggctgaaac agcttcccag cggcgttctc gcgggacact gccgcctcac
    14761 tacctcggcg gcgttcacaa acgtgccgcg ctttattcag cgcgtcgtga acctctcaga
    14821 ctcaacgtac cgcaagggta cgcctcgcct tgctgcggct tttctcgacg aactgtttga
    14881 acagcttgag agcggggaac gaacgtcact tcacgaatga cgtgtgaaag gctcgtctca
    14941 ctgggcagcg ggagagctgg acacggctcc tgtgtccagg agcacgccgg agttatcgaa
    15001 aggcaagcgg cctgccttgg tgtggaccac gcctgtcagg tgataagtca gcggctgatt
    15061 gccggagaac gacaacagct gcctgacgac ctggagggtg g
//
LOCUS       DAOQPD010000094        14751 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_2074_length_14751_cov_16.158615, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000094 DAOQPD010000000
VERSION     DAOQPD010000094.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 14751)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 14751)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14751
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2074_length_14751_cov_16.158615"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(8..667)
                     /locus_tag="PK063_16350"
     CDS             complement(8..667)
                     /locus_tag="PK063_16350"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98673.1"
                     /translation="MGLETANYIHELNSANPTTLDQKSQGDDHLRLIKAVLKATFPNL
                     TGAMTADQAELNQLDGTTISAFAKTILDDADASAMLTTLGFSAFIKTLLDDADAAAVR
                     TTIGAGVGNALLSAVQTWTAAQRGTITTDNDLSFDLSVTNYFVCTPTAGGTLTFTNIP
                     SGQPVAIKLVNGSNYAIAAHANTKISFADLTRISVTGTYLLTGLADGTNVLLTASANL
                     A"
     gene            complement(669..1298)
                     /locus_tag="PK063_16355"
     CDS             complement(669..1298)
                     /locus_tag="PK063_16355"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98674.1"
                     /translation="MTRDEIVTLLQYRCGDRNDLGPKILAEMKMVQTQILEEHPWLPW
                     FCETSLTIPTALVSGTETLVLPTDFLREIEDERIWLVNSLGSKRELDKYASGQIRTRF
                     ALNGSPAAYALLASDILFRPIPEENYTIEWRYYGAQADMSATAGTTPWTQYASAVVIA
                     EVGAVIAGRHILNPTLEAQFRNDATVAWDNLYKKHEARQDVNREPVLGG"
     gene            complement(1352..2011)
                     /locus_tag="PK063_16360"
     CDS             complement(1352..2011)
                     /locus_tag="PK063_16360"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98675.1"
                     /translation="MSDIFRCVVGVPSGQSWNAQFGVDLVNLLIGVGQKPIPGYRGMD
                     VRLVNVRSSILSKNRMDLVKAARQLKATHLLFIDSDQTFPSYLLHKLASWGKLVVAAN
                     CVTKQIPANPTARAKSANPKGEIVYTDPHSTGLEQVWRVGTGVMLINMKVFDKIGMGV
                     WDMKYLPEEETYQGEDWTFCEACENAGIPLYIDHDVSKMVGHVGNYEFTHDVVGTVAT
                     S"
     gene            complement(2018..2569)
                     /locus_tag="PK063_16365"
     CDS             complement(2018..2569)
                     /locus_tag="PK063_16365"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98676.1"
                     /translation="MAIVGIFDSVAAPQGWFQHDAPPPGWFDESLLAVGAAGGAYTLT
                     AQGGSYALTGQSATLLRSKRIVASGGAYAVAGASAALLRSKRLIASGGAYAWTGASAG
                     LSRNRRLTAQGGSYTYTGANAVITRVGIVWPDPSQVLSGVSYGPTGVEYTGTFQGLSM
                     SLKLDLTTGMLVKPLNDKTVLSL"
     gene            complement(2573..2746)
                     /locus_tag="PK063_16370"
     CDS             complement(2573..2746)
                     /locus_tag="PK063_16370"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98677.1"
                     /translation="MILIGIDQGTVVLCVSIDPEQLPHCQEMYPDWILQEQIGEETIG
                     WTFDGSSFAPPSE"
     gene            complement(2743..3930)
                     /locus_tag="PK063_16375"
     CDS             complement(2743..3930)
                     /locus_tag="PK063_16375"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98678.1"
                     /translation="MILLTSTSDIIRVVTSAAANSIDVHASYVDLSGTTVTPGRTNTK
                     ITTATTTTIVPSPGGSTQRNLKGLYVTNNSVGTNCTIAVQHYDGTNSVELIEVVLLPG
                     ENLGYREDGSWVHRDQNGAEYPPSGLGAYTGYAIPFMKAGTAADTTGYWYCSSKDSGF
                     PGAWAPGTPGLNGRATDGTNSADYGCIPLINASSGNNFLTEIQMAGSTNHSHLFFDCL
                     WVNSGIVVTTTTAQALASVALPARDINGTTNGEGCQIAMLTTTANTNAAAIANATVSY
                     TNSKGVSGRTATLTAIAGSQITITPVIGTITWFNLQAGDTGVMSIESITLGTSLGAGA
                     VSFMITRDIATIGTTVANVTAQKVIGAPGIKLYNGTCLLHCYLASATTATFMSGELTV
                     MQK"
     gene            complement(3933..4352)
                     /locus_tag="PK063_16380"
     CDS             complement(3933..4352)
                     /locus_tag="PK063_16380"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98679.1"
                     /translation="MPTASYVKVAAANEDLVEGINAGTDQWAVALTNTVPGGKTFVAG
                     TTDLATGGGYTQGGANVSTNSSGMNGSDFVLVLADPAVWTGSGGGFTFRYALLVNKTN
                     NIVVGYWDYGSSQAVAAGETVTVDLDQTATVGVFKVT"
     gene            complement(4362..4676)
                     /locus_tag="PK063_16385"
     CDS             complement(4362..4676)
                     /locus_tag="PK063_16385"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98680.1"
                     /translation="MSNDFVRRSAADIGKMLDAEKLQVENLDVHRLRVMIAPVTLKYE
                     DAGGGVAYVGEAVPGTALSAAGWRIKKILTTVAGVDILWADGDSNFDNVWDDRASLTY
                     TP"
     gene            complement(4669..4947)
                     /locus_tag="PK063_16390"
     CDS             complement(4669..4947)
                     /locus_tag="PK063_16390"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98681.1"
                     /translation="MATIDGIASGLDQREPRVHFDLDREEAKEVKAFRPGQVVKITLV
                     GTVESMNFRKPDDPDLSGYEGSLTVKMRDMDIGLSSKNAIAELLDDDE"
     gene            complement(5024..6226)
                     /locus_tag="PK063_16395"
     CDS             complement(5024..6226)
                     /locus_tag="PK063_16395"
                     /inference="COORDINATES: protein motif:HMM:NF036552.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 family protein"
                     /protein_id="HMZ98682.1"
                     /translation="MAVAGLRGTGDWATDERPKNFREMILWRNPNGMAPLTALLSKMK
                     TESTSDPEFAWYEEELNALRLTVNYTTGYATTDTAIAVTSNVTDATDVVAGDVFLVEK
                     ALTTAYNHEIIIASANGAAGSVTFTRAQCGTAAAPLANGTFLTKIGNAFAEGTGAPSA
                     STRNPTKMYNLCQIFKTTYDITNTAKGTKTRTGDPVKNDKKRKMFDHSTAMEMAFLFG
                     KRHETTGSNGKPLRFTGGLLWFLSQYASSMITAFTTTPTETTFTDAVYKVFDYDSGAG
                     DERIVFAGNGFLNSLNKLAASQSRTRVHFDGIIDVYGMKLQHWVLPQGTIYVKSHPLF
                     NVHSRFTNDAAIIDPSALKYRTFRDTTFKDNIQSNDADETKGQWLSEVGLELEHAKTM
                     GWISNFVV"
     gene            complement(6238..7134)
                     /locus_tag="PK063_16400"
     CDS             complement(6238..7134)
                     /locus_tag="PK063_16400"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98683.1"
                     /translation="MLIHKLLRRFMDEAGGAEDGGAGGGVPAPAAEPAEASTEADVNW
                     ADMADALEADDAGEDQGQVEGDAEIVGETPAVATPAVETPPVTPPVAETPPVTPPTET
                     PPTAPVTPPTPETPAPDYTAWRTERLGQLEQQYALNEADAAALLTEPETVLPKLAAAV
                     HMEVLESAMRGMQAMMPVLMQQVNQHTELNTRAKNLFTSINPDLADPQFEPAIMQLGQ
                     VYRNVNAKASPEEAARAIGNLVRSALGIAAPAVAAPSAPAAAPVAPVPFTPARGGGSG
                     NAPLPASNAFTQLANEFLQDDY"
     gene            complement(7121..7429)
                     /locus_tag="PK063_16405"
     CDS             complement(7121..7429)
                     /locus_tag="PK063_16405"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98684.1"
                     /translation="MDIDKMEEVGNLAQAKRDWEELISNPAWAQLVKAVQEQVDGLQQ
                     QVLFAPITDENNLYMVERQKGMLEGRLSLQTTAQALMESVALDFNMAVAKKGTENADS
                     "
     gene            complement(7429..9354)
                     /locus_tag="PK063_16410"
     CDS             complement(7429..9354)
                     /locus_tag="PK063_16410"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98685.1"
                     /translation="MKTAEKLAPGIKHIPFGSKLHNLIITNFKSRLDLSRDEQRKKRE
                     ESWKTSEDTFTAYMPADEVDSLRKSGRKSGDTEYTTIAIPYSYAMLLTSHTYYTSVFL
                     ARDPIFQFKGRHGESQDAETALESLIDYQLNAGNNLVPLFIWLMDIGKYSHGVVGHYW
                     DKEEFTFTQLREVPRTFMGLPIPGTSEKKLISETKVGYEGNRLYNVRPQDFMTDPRVP
                     LVRFQDGEFCIVFDKVGWVQVASRAASGKYFNVNMLKKEGSYSSEDRLATGNDTNLPG
                     EDLPTYFGTEGSEYPATVDLHEFHWTIIPSELGVGTSSRPEKWVFTIANKRIVISAQP
                     LGLIHNRYPFDVIPFEVEGYNVFNRSMLEVLDPLNKTMEWLFNSHFFNVRAALNNMFL
                     VDPSRVNTRDLEDPGPGKMIRLKPAAYGQDVRTLMSQFPVADVTRSNLADSDYVAQLS
                     QRITGVSDNVMGQVNTGGRKTATEVRSSTTFGINRLKTNCEWFSACGFAPLGQKLVMS
                     TQQLYAAERKYRIVGDQAQWGAAYLNVNPDMIAGFYDFVPVDGTMPVDRFAQVNLWQQ
                     MLGSLSKVPGMLQQYDLGKLFAFVAQLGGLKNVNRFRIQVVPDGAMINGVQAGNVVPM
                     RGNMNEPGQIPGMGSTG"
     gene            complement(9351..10808)
                     /locus_tag="PK063_16415"
     CDS             complement(9351..10808)
                     /locus_tag="PK063_16415"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98686.1"
                     /translation="MQDGKLAITPQDAVRLGATSLTRYGRLFFPKTFRQSSPGFHDEI
                     GGALLNRDYRNVAIEVFRDGAKTTLLRVFTSQRIAYGISRTILIVSASQGHSILSLRW
                     IKRQVEHNRLWAQTFHLKKGTKWTDDHVEIIHGAFDTPITLLALGITGQLRGFNIDDH
                     RPDLIICDDTSTDETSSSPEQRRKETNLVFGALLNSLAPSSEAPDAKAVILDTPKSKF
                     DLIESCEKNPDWKFFRFGIFDAEGESRWPERYPTAELKLRKENAIKVGQLPIWMKEKE
                     CRIIAEELASFKASNLIYWDTLPPNATYVITIDPASSDSKDADDNVVAVVAFYKDEVY
                     VVDYKAATGQNPEMVKATVFEFARRWRPLGVVVESIAYQRVLAWYLEKEMRENRVYLP
                     VWQVQDRRRKSDRIIQALGETSGYHRLKCLPSHTKFIEQFTEYSPTADMHDDVLDAIA
                     MAVTWGERQGVDDWIEGEYSELEDDMPLLSFRNAP"
     gene            complement(10808..>11334)
                     /locus_tag="PK063_16420"
     CDS             complement(10808..>11334)
                     /locus_tag="PK063_16420"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98687.1"
                     /translation="PLLSKGKFLKSSPPPAPSSFRPAGRVLSAAFCLPPAIRKKRYTG
                     RRLAGIRYERKVHEYLELLYGDKYVASPWLRFYTEAGWRWCQPDGLLVDLQRGRITII
                     EVKYQHTSDAWWQVRHLYQPVLEKMFPSELWELDACEVVKWYDPATVFPEKVVLAQEV
                     AMHHPSFKVHIWRP"
     assembly_gap    11335..11434
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<11435..11899)
                     /locus_tag="PK063_16425"
     CDS             complement(<11435..11899)
                     /locus_tag="PK063_16425"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98688.1"
                     /translation="MAESKQLVNLSHTHEMLMNWLVLNPEKSLRECADHFGYTQSWLS
                     SIIHSDIFQAALKEKQLAIQARVAGSIPEKLRRSADIALDKLATKLEETEDPEFILDA
                     TDKILHRMGYAPASSRNPAGPPSGHVHQQNNFFVTGADISAARELMQASSGLA"
     gene            12292..>12797
                     /locus_tag="PK063_16430"
     CDS             12292..>12797
                     /locus_tag="PK063_16430"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98689.1"
                     /translation="MATNANVKFLSKVLPTDINGKAGTVSCVLGNGLRVEVEVAGLSD
                     EIRERLMYHGLSQKLGDSAAGFSKDRDFSGAFAAIQSTADNLIAGVWASRASSGISDL
                     VAAIADIRGVSVEIAQAAVDKMTEDQVSAVRKHPAVKKAIADMQAARLAAAAENSASS
                     LDDLMEDLG"
     assembly_gap    12798..12897
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            13407..13877
                     /locus_tag="PK063_16435"
     CDS             13407..13877
                     /locus_tag="PK063_16435"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98690.1"
                     /translation="MESSNAAGKPVRNIRKDTVTWRLFEHYFLMQEASAYPLRIPCET
                     WGQALNLSVGLNRCHVQHQRETGMPDEAMLYSAKPVRNPENTEFWIEVSTNYRRQGLA
                     SPSKLARQAGGNWMENLLVQAESTLLPAPTPESTQPVPDKMESLLDTFMKGEVK"
     gene            14082..14585
                     /locus_tag="PK063_16440"
     CDS             14082..14585
                     /locus_tag="PK063_16440"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98691.1"
                     /translation="MDLTNQQVTLRQARIEELEAELAKEREKGKLKEKQISDLLAEVV
                     FEVSTPRIRELEDKISAMALEALSAEGQWIEHTAAQQATIAEMKKAIAAWERAEAGQE
                     LQEAEAKLIVIMNIESNLDALHEARALECERLADVAGDEPEHVKAMFSEWLREEAAAH
                     RARKEEK"
BASE COUNT         3088 a         4241 c         4047 g         3175 t
ORIGIN      
        1 aggatcgtca tgccagattc gccgatgcgg tcaggaggac gttggtacca tccgctagac
       61 cagtgagtag gtaggttccc gtgacgctga ttcgcgtcaa atctgcaaag ctgatcttcg
      121 tgttcgcgtg cgcagcgatc gcgtagttgc tgccattcac cagcttgatc gctaccggct
      181 gtccgctcgg aatgttcgtg aatgtgagcg tgcctccggc agtcggggta cagacaaagt
      241 agttcgttac cgacagatcg aacgagaggt cattgtcggt agtgatcgta ccacgctgcg
      301 cggctgtcca ggtttgcaca gcactcagta aagcattacc tacacctgcc ccaatcgtgg
      361 tgcgcacagc cgccgcatct gcgtcatcca ataacgtctt tataaaggcc gaaaatccca
      421 acgtagtcag cattgccgag gcatctgcat catcgaggat agtcttggca aaggccgaga
      481 ttgtcgtacc atcaagttga ttcaactccg cctgatccgc cgtcatcgct ccggtaagat
      541 tcggaaacgt ggccttgagt accgccttga tcaagcgtag atggtcatcc ccctgactct
      601 tttgatccag ggttgtcggg tttgccgagt tcagctcatg aatatagttt gcggtttcaa
      661 gtcccatctc agcctccgag caccggctcg cggtttacat cctgtcgagc ttcgtgtttc
      721 ttgtacaggt tatcccaagc cacagttgcg tcattccgaa actgagcttc caaagtcggg
      781 ttgaggatat ggcgtcctgc aatgaccgca ccaacctctg caatcaccac cgcactggca
      841 tactgtgtcc acggagtcgt tccagcagtt gccgacatat ccgcctgtgc tccgtaatac
      901 cgccattcga tagtgtaatt ctcttctggg atcggacgga aaaggatatc agaagccaat
      961 agcgcatagg ctgcagggga tccattcaag gcgaatcgag tgcgtatttg ccccgaagcg
     1021 tatttatcca gctccctctt acttcccagg ctgttcacca accaaatgcg ttcatcctcg
     1081 atttccctta gaaaatccgt aggtaatacc aacgtttccg tccccgagac tagagccgtg
     1141 ggaattgtca atgaagtttc gcagaaccag ggaagccaag gatgctcttc cagaatctgg
     1201 gtctgcacca tcttcatctc agccagaatc tttgggccaa gatcattacg atcaccgcag
     1261 cgatactgta acagcgtgac gatttcgtct ctagtcatga taactccttt ttcttaccgt
     1321 aacagtacca ctttggccct gtcaaggaaa attaacttgt agcaacagtc cccacaacgt
     1381 catgggtgaa ctcgtagttc ccgacatgac ccaccatctt ggagacgtcg tgatcaatat
     1441 ataagggtat accggcgttt tcgcaagctt cgcagaaagt ccaatcctcc ccctgatacg
     1501 tttcttcctc aggaagatac ttcatatccc agacgcccat gccgatctta tcaaagacct
     1561 tcatgttgat cagcatcaca cctgtgccca cgcgccagac ctgctcgagg ccagtcgaat
     1621 gcggatcggt gtagacgatt tcccccttcg ggtttgcgct tttcgcccga gcggtgggat
     1681 tcgccggaat ctgcttcgtg acgcagtttg ccgccacgac cagcttaccc caagaggcaa
     1741 gcttatgcag aaggtaactc gggaaggtct ggtcggagtc gatgaaaagc aaatgcgtcg
     1801 ccttaagctg gcgagctgct ttcaccaagt ccattcggtt cttggagagg atactcgacc
     1861 gcacattaac cagtcgaacg tccattcccc tgtaacccgg aatcggcttt tgtcctaccc
     1921 cgatcagcag attcaccagg tcgaccccga actgcgcatt ccagctttgc ccactcggca
     1981 cccccaccac acaacgaaag atatcagaca taaatcctca caaggagaga acagttttgt
     2041 cgttcaacgg cttgaccagc atacccgtcg tcagatcaag tttaagggac atggacagtc
     2101 cctggaaagt accagtatat tccacgcccg ttgggccgta ggacacaccg gaaagaacct
     2161 gcgaagggtc aggccacact atgcccacgc gggtaattac tgcattcgcc ccggtatagg
     2221 tgtaactacc cccctgggcc gtcaaccgtc ggtttcgact gagtcctgca gatgctcccg
     2281 tccaggcgta tgccccaccc gaggcgatca gcctcttact ccgcaggaga gcggccgagg
     2341 caccagccac ggcataggcg cctccactgg ctacgatccg tttcgagcgc agcagcgtgg
     2401 ccgattggcc tgttaacgca tagctaccac cttgagccgt gagtgtgtaa gcaccgccgg
     2461 ctgccccaac tgcaagcaga ctttcatcga accagccggg tggcggagcg tcgtgttgga
     2521 accacccctg gggcgctgcc accgagtcga aaattccaac tatcgccatg gcttactccg
     2581 aaggaggcgc gaagctacta ccatcaaatg tccagccgat ggtttcctcc ccgatctgct
     2641 cctgcaaaat ccagtcagga tacatctcct ggcaatgcgg cagttgctcc ggatcgatgc
     2701 tcacgcacag gacgactgtg ccttggtcaa ttccgatcag aatcatttct gcatcaccgt
     2761 aagttcgccc gacatgaatg tcgccgtcgt agcactggca aggtagcagt gcagcagaca
     2821 ggtgccgttg tagagcttga tgcccggagc gccgataacc ttctgcgccg ttacgttggc
     2881 gacagttgtg ccgatggtgg cgatgtcgcg ggtaatcatg aaactgactg cgccggcccc
     2941 aagcgacgtg ccgagagtga tcgactcgat agacatcaca ccagtgtcgc cggcctgcag
     3001 attgaaccaa gtgatcgttc cgatgaccgg ggtgatcgtg atctgcgagc ctgcgatagc
     3061 cgtaagggtt gcggtgcggc ctgatacgcc cttgctgttc gtgtagctga cggtcgcgtt
     3121 cgcaatcgct gcggcgttgg tgttcgccgt ggtcgtcagc atggcgatct ggcagccttc
     3181 gccgttggtc gttccgttga tgtcgcgagc cgggagtgcg accgaggcca gggcctgcgc
     3241 cgtcgtggtc gtgacgacga tgccgctgtt cacccacagg cagtcgaaaa acaagtgcga
     3301 gtgattggtg ctaccggcca tctggatttc ggtcaggaag ttgttaccac tcgatgcgtt
     3361 gatgagcggg atacagccgt agtccgcgct gttcgtgccg tcggttgcgc gaccgttaag
     3421 accaggagta ccgggtgccc atgcgccggg gaagccggag tccttcgacg aacagtacca
     3481 gtagccagtc gtgtccgctg ctgtacctgc cttcatgaac ggtattgcgt agccggtgta
     3541 ggcgccgagg cccgacgggg gatattcggc cccgttctga tcgcgatgca cccacgaccc
     3601 atcctcacga tagccgaggt tttcaccggg cagcagcacg acttcgatca gctcaacaga
     3661 gttcgtacca tcgtagtgct gtaccgcgat ggtgcagttc gtaccgaccg agttgttcgt
     3721 gacgtacaac cctttcaggt tgcgctgcgt tgacccaccc ggcgagggga caatggtcgt
     3781 ggttgtcgca gtcgtgatct tcgtgttagt gcgccccggc gtgaccgtgg tgccactcag
     3841 gtcaacatat gaggcatgca cgtcgatgct gttcgccgca gcggacgtga cgacacggat
     3901 gatgtcagag gtactggtca ggaggatcat gatcaggtca ccttgaacac gccgacggtg
     3961 gcggtctggt cgaggtcaac agtgacggtc tcacctgcgg ccactgcctg ggagctgcca
     4021 taatcccagt acccgacgac gatgttgttc gtcttgttga ccagcagggc atagcggaag
     4081 gtaaagcctc caccactccc tgtccacacc gccgggtcgg ccagcaccag cacgaaatcc
     4141 gagccgttca taccgctcga gttcgtactg acgttcgcgc cgccctgcgt gtatccgcca
     4201 cccgtcgcca ggtcggtcgt gcctgcaacg aaggtcttgc ccccaggcac ggtattcgtc
     4261 agggcaacag cccactggtc agttcctgcg ttgatgccct ccaccagatc ctcgttggca
     4321 gcggcaacct ttacatatga tgcagtaggc atatgccctc cttacggcgt gtaggtcagg
     4381 ctggccctgt cgtcccacac attgtcgaaa ttactatccc catcagccca cagaatatcg
     4441 actccggcca ccgttgtcaa tatcttctta atccgccaac ccgccgcgga gagggcagtc
     4501 cccggaaccg cttcaccgac gtaagcaacg ccgcccccgg catcttcata cttcaaagta
     4561 accggggcga tcattacccg caagcgatgg acgtcgagat tctccacctg gagtttctcc
     4621 gcgtccagca tcttgcctat atcggcagcg cttcgccgaa cgaagtcatt actcatcgtc
     4681 gtcgagcaac tcagcgattg cgttcttcga ggagaggccg atatccatat cccgcatctt
     4741 cacggtcagg ctaccttcat accccgacag atccgggtcg tccggcttgc ggaagttcat
     4801 gctctccacc gtgccgacca gggtaatctt caccacttgc ccaggacgaa aggccttaac
     4861 ctctttcgcc tcttcccgat ccaggtcgaa atgaacccgc ggctcgcgtt gatccagccc
     4921 gcttgcgatt ccatcaattg ttgccactgt attctcctcg aaaaaatggg gacattaatt
     4981 attagttaat gtccccatct attaccagct tacgccggcc cgcttagacc acgaagttgg
     5041 agatccaacc catcgtcttg gcgtgttcca gttccaggcc gacttccgac agccactgac
     5101 ccttggtctc gtccgcgtcg ttcgactgga tgttgtcctt gaaggtcgtg tcgcggaagg
     5161 tacggtactt cagggccgac gggtcgatga tcgctgcgtc gttcgtgaag cgggagtgga
     5221 cgttgaagag ggggtggctc ttcacataga tggtgccttg cggcagcacc cagtgctgga
     5281 gcttcatccc gtagacgtcg atgatgccat cgaagtgcac gcgggtgcga ctctgactcg
     5341 cggccagctt gttcagcgag ttcaggaagc cgttaccggc gaacacgata cgctcgtcac
     5401 cggcaccgct gtcgtagtcg aacaccttgt acaccgcatc ggtgaaggtg gtctcggtcg
     5461 gcgtggtggt gaaggcggtg atcatcgagc tcgcgtactg cgacaggaac cacagcagac
     5521 cgccggtgaa gcggaggggc ttgccgttcg agccggtcgt ctcgtgacgc ttgccgaaca
     5581 ggaaagccat ttccatggcc gtcgagtggt cgaacatctt gcgcttcttg tcgttcttga
     5641 ccggatcgcc agtacgggtc ttggtgccct tcgccgtatt ggtgatgtcg taggtggtct
     5701 tgaagatctg gcacaagttg tacatcttcg tcgggttacg ggtgctggcc gacggggcgc
     5761 cagtaccttc cgcgaaggcg ttgccgatct tggtcaggaa cgtaccattc gccagcgggg
     5821 ccgcggccgt accgcactgc gcacgcgtga acgtcaccga gccggctgcg ccgttggccg
     5881 aggcaatgat gatttcgtgg ttgtaggccg tggtcagcgc cttttccacg aggaacacgt
     5941 cgcctgcaac cacgtcggta gcgtccgtca cgttcgaggt caccgcgatc gcggtatcgg
     6001 tcgtggcgta gccggtcgtg tagttgacgg tgaggcgcag cgcgttcagc tcttcttcgt
     6061 accaggcgaa ttccgggtca ctcgtcgact cggtcttcat cttggagagg agagcggtca
     6121 gcggtgccat accgttcggg ttccgccaga ggatcatctc gcggaaattc ttcgggcgct
     6181 cgtcggtggc ccaatcacca gtaccgcgca aacctgcaac agccatgatg cttctcctta
     6241 gtaatcatcc tgaaggaact cattggccag ctgggtaaac gcattcgacg ccgggagagg
     6301 cgcattcccc gatccgccac ctcgggcggg agtaaagggg acaggcgcca ccggggccgc
     6361 tgcgggggca ctcggcgctg caactgccgg ggccgcgata cccaaagctg accgtaccag
     6421 attgccaata gcgcgagcgg cttcctcggg gctggctttc gcattcacat tgcgatagac
     6481 ctgcccaagc tgcatgatcg ccggctcaaa ctgcgggtcg gccagatccg gattgatcga
     6541 ggtgaaaaga ttcttcgccc tcgtgttcag ctccgtatgc tggttcacct gctgcatgag
     6601 tacgggcatc atcgcttgca tgccgcgcat cgcgctctcc agaacctcca tgtgcaccgc
     6661 agccgcaagc ttcggcagta cggtttccgg ctcagtcagc agggcagcag catcggcctc
     6721 attcagggca tactgttgct ccaactggcc aaggcgttcc gtgcgccaag cagtgtagtc
     6781 gggtgccggg gtctccggag tgggcggagt aaccggagca gtcgggggag tttccgtcgg
     6841 cggagtaacc gggggagtct cagcaaccgg cggagtgacc ggaggggttt ccactgccgg
     6901 tgtcgccacc gcaggagtct cccccacaat ttccgcatcg ccttcaactt gaccctgatc
     6961 ctcgccggcg tcgtcagcct ccaacgcgtc agccatatca gcccaattaa catcagcttc
     7021 cgtcgaagcc tcagcaggtt cagcggcggg agccgggaca ccgccccctg caccaccgtc
     7081 ttcggcccca ccagcttcgt ccatgaagcg gcggaggagt ttatgaatca gcattttcgg
     7141 ttcccttctt ggccacggcc atgttaaaat ccagtgctac actttccatc agagcctggg
     7201 cggtcgtctg caagctcagc cggccctcca acatcccctt ctgccgctcg accatgtaca
     7261 gattattctc atccgtgatc ggagcgaaca gaacttgttg ttgaagcccg tccacttgct
     7321 cctgcaccgc cttcaccaat tgtgcccacg cgggattaga aatcaactcc tcccaatccc
     7381 ttttcgcttg agccaggttg cccacctctt ccatcttgtc gatatccatc agccggtact
     7441 ccccatgcca ggaatctgcc caggttcatt catattccct ctcatgggaa ccacattccc
     7501 ggcctgtacg ccgttaatca tagccccatc aggcacgact tgaatccgga acctgttgac
     7561 gttcttcaag ccgccgagtt gcgccacgaa ggcgaagagc ttgcccaggt cgtactgctg
     7621 cagcataccg ggaaccttgg acagactccc cagcatctgt tgccacaggt tgacctgagc
     7681 aaaacggtca accggcatcg tgccgtcgac tggcacgaaa tcgtaaaagc ccgcgatcat
     7741 gtcaggattc acattcaggt aggccgctcc ccactgagcc tgatccccca caatccgata
     7801 cttgcgctca gccgcgtaca gctgctgcgt ggacatgacc agcttctggc ccagcggggc
     7861 aaacccacag gccgagaacc attcgcagtt cgtcttcagc cggttaatgc cgaaggtggt
     7921 tgacgagcgc acttccgtcg cagtcttgcg cccgcccgtg ttcacctggc ccatcacatt
     7981 gtcgctgacc ccggtgatgc gctgggaaag ctgcgccaca taatcgctat ccgccaagtt
     8041 cgagcgggta acatccgcga ccgggaactg ggacatgagc gtccgcacgt cctggccata
     8101 ggcggcgggc ttcagcctga tcatcttgcc cgggcctgga tcttccaggt cgcgcgtatt
     8161 cactcgcgag ggatcgacga ggaacatatt gttcagcgcg gcccgcacgt taaagaagtg
     8221 ggaattgaac agccactcca tcgtcttgtt caggggatcg agcacttcca gcatcgaacg
     8281 gttgaagacg ttgtagcctt ccacctcgaa cgggatcacg tcgaaggggt agcggttgtg
     8341 gatcaggcca agcggctggg cactgatcac gattctctta ttcgcgatag tgaacaccca
     8401 cttttccggt cgggaggagg tgcccacccc cagctccgac gggataatcg tccagtggaa
     8461 ttcgtgcaaa tccaccgtag cgggatactc ggacccttcc gttccgaagt acgttgggag
     8521 atcctcgccc ggcaggttgg tgtcgttgcc cgtggccagt cgatcttccg agctatagct
     8581 cccctctttt ttcagcatgt tgacgttgaa gtacttgccc gaggcggccc ggctcgcgac
     8641 ttgtacccag ccgaccttgt caaacacgat gcagaattca ccgtcctgga atctgaccag
     8701 cggaacgcgg ggatcggtca tgaagtcttg cggccgcaca ttatacagcc ggttcccctc
     8761 atacccgacc ttggtttcgg agatcagttt cttctccgag gtgccgggaa tcggtaggcc
     8821 catgaacgtg cgcggcactt cccgcagctg ggtaaaggta aactcttcct tatcccagta
     8881 atgcccgacc accccatgcg aatacttgcc gatatccatc agccagatga acagcggaac
     8941 caggttattc ccggcattca gctggtaatc aatcagactt tccagtgctg tctccgcgtc
     9001 ctggctctcg ccgtgccggc ccttgaactg gaagatcgga tccctggcga ggaagaccga
     9061 ggtgtagtac gtatgactgg tgagcagcat cgcatacgag tacggaatcg cgatagtcgt
     9121 gtactccgta tccccgctct tccgtccgga cttgcgcaga ctgtccacct cgtccgccgg
     9181 catataggcc gtgaaggtgt cctcgctcgt cttccaggat tcttcccgtt tcttccgctg
     9241 ctcgtcccgg gacagatcca gccgggattt gaagttcgtg atgatcaggt tatgaagctt
     9301 actcccaaag ggaatatgct tgattccggg ggccagcttt tcagcagtct tcatggtgca
     9361 ttcctaaaag aaagaagggg catgtcgtct tccagttcac tatactcgcc ctcgatccag
     9421 tcatcgacgc cctgccgttc gccccaggtc acagccatgg caatcgcgtc cagcacgtca
     9481 tcgtgcatat cagccgtagg tgagtattcc gtaaactgct caatgaattt cgtgtgcgac
     9541 gggagacact tcaaccgatg gtagcccgag gtctcgccaa gcgcctggat aatacgatcc
     9601 gacttacgtc ggcgatcctg cacttgccag acgggaaggt agacgcggtt ttccctcatc
     9661 tccttctcca gataccacgc cagcacgcgc tggtacgcga tactctcaac taccacgccg
     9721 aggggtctcc acctccgcgc gaattcaaag acggttgcct tcaccatctc agggttttgg
     9781 ccagtcgcgg ccttgtaatc tacaacatac acctcgtctt tgtagaaagc aactactgcc
     9841 accacattat catccgcgtc cttgctgtcg ctcgaggccg ggtcaatcgt gatcacataa
     9901 gtggcattcg gcgggagcgt atcccagtag atcaggttac tcgccttgaa gctcgccagc
     9961 tcctccgcga taatccgaca ctccttctcc ttcatccaga tcggcagctg cccaaccttg
    10021 atcgcgttct ccttgcgcag cttaagttcc gccgtcgggt accgctcagg ccaacgcgac
    10081 tcgccttctg cgtcaaaaat gccaaaccgg aagaatttcc agtccggatt cttttcgcag
    10141 ctttcgatca ggtcgaactt gctcttgggg gtgtcgagga taacagcctt agcgtcgggt
    10201 gcctcggagg agggtgccag cgagttgagc agtgcaccaa agacaaggtt ggtttccttc
    10261 cgccgctgtt cgggagaaga actcgtctcg tcagtagagg tgtcatcgca gatgataagg
    10321 tcaggacgat gatcgtcgat gttaaagccg cgaagctggc ctgtaatgcc aagtgcgagg
    10381 agagtaatcg gagtgtcgaa ggccccatgt atgatctcca catgatcgtc agtccacttc
    10441 gtacctttct tcaggtggaa ggtctgcgcc cagagccggt tatgctccac ctgccgtttg
    10501 atccacctca gggatagaat cgaatgacct tgactcgccg aaacaataag aatcgtccgc
    10561 gagataccat atgcgatccg ctggcttgtg aacactcgca gtagcgtggt tttcgctccg
    10621 tcccggaaaa cctcaattgc cacattacga tagtctcgat tgagcagagc cccgccgatc
    10681 tcatcgtgaa agccaggaga agactgtcgg aaagtctttg gaaagaacag acgaccgtac
    10741 cgggtaaggc tcgtagcgcc gagccgaacc gcgtcctgcg gggtgattgc gagtttgcca
    10801 tcttgcatca aggcctccag atatgcactt tgaaagaggg atggtgcatg gctacttcct
    10861 gcgcaagcac caccttctca gggaaaacgg tagccgggtc gtaccactta acaacttcgc
    10921 acgcatccag ctcccacaac tcggagggga acatcttttc cagcacgggc tggtacaaat
    10981 gccgaacctg ccaccacgcg tccgaggtgt gctgatactt cacctcgatg atggtgatcc
    11041 ggccgcgctg gaggtccacc agcaacccgt ccggctggca ccagcgccaa cccgcctcgg
    11101 tgtagaaccg aagccagggg ctcgccacat acttgtcccc gtagaggagt tccaggtact
    11161 catgcacctt ccgttcataa cggataccag ccagacggcg gccggtatag cgcttcttac
    11221 ggatggcggg gggtaggcag aaggcagcgc tcagcaccct tccggcgggc cgaaaactac
    11281 tcggcgcggg gggcgggctg gacttcaaga acttcccctt cgataacagt ggcgnnnnnn
    11341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnncgcgag accggaactc gcttgcatca
    11461 gctcccgcgc ggccgagata tcagctcccg tcacgaagaa gttgttttgc tgatgtacgt
    11521 gcccactcgg gggcccggcg gggttacggc tggacgccgg cgcgtagccc atccggtgga
    11581 ggatcttgtc cgtggcgtcg agaatgaact cgggatcctc ggtctcttcc agcttggtcg
    11641 cgagcttgtc cagggcgata tccgcgctcc ggcgaagctt ctccgggatg ctccccgcca
    11701 cgcgggcctg gatcgcgagc tgcttctcct tcagcgcggc ctggaagata tccgagtgga
    11761 tgatggagga cagccaactc tgcgtatagc cgaaatggtc ggcgcactcc cgaagggact
    11821 tctccgggtt cagcacgagc cagttcatca gcatctcgtg cgtgtggctg aggttcacca
    11881 gctgcttact ttcggccatt cccggctcct gtatatgtgt tgccaagact ctacttcgac
    11941 cgcacgggtt tgtcaagagg gggcacctcc ggggcgggct cagggggctg gccgggctgg
    12001 cgcgtgggat tgatggggag agtaatttag aattaatgtc cctattaatt cccaaaatct
    12061 ctcagtaacc tgagtggaca atcccccagg catagggcca tgcgaagggg ggtggccggc
    12121 cccctctgta agtcgttgat tagacggcac ttttttccga gcttgcaatc cccagccagt
    12181 ggtatatact acagacatgg gtaggtgatg acgaccgacc cagccggtag gcagccaggt
    12241 gtgcagcctg tccgggggcg atttgcccga ttctttaaca aggagagtat tatggctacc
    12301 aatgccaacg tcaaattttt gagtaaggtt cttccgactg atatcaatgg caaggccggg
    12361 acggtttcct gcgtgttggg gaatggcttg cgcgtggaag tggaagtcgc cgggctgtcg
    12421 gatgagatcc gggagcggct gatgtatcac gggctgagcc agaagttggg cgatagcgcg
    12481 gcgggcttca gcaaagaccg ggatttttcc ggcgcatttg cggcgattca gagcacggcg
    12541 gataacctta tcgccggggt ctgggcgagc cgtgcaagca gcgggattag cgatctggtc
    12601 gcggccatcg cggatattcg cggggtgtct gtggaaatcg cacaggcggc tgtggataag
    12661 atgacggagg atcaggtcag cgccgtcagg aagcatccgg cggtgaagaa ggcgatcgcg
    12721 gatatgcagg cagcacggct tgccgcggcc gccgagaact ccgccagcag cctcgacgac
    12781 ctgatggaag atctcggnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnccc
    12901 ttgcaaacag gtgcaaagcg atgcaaagcg atgcaaacaa ctgcaaaggg tgcaaagggc
    12961 caaagaaact cgcctacccc catatccggc ctgttcttgt ccccattaat tattctccgg
    13021 cccattaatt actaagcttt ttatctctcg ggctagtatt aaggaaattt tttttttttt
    13081 ttttttttac taactgagga gggacatact aattaaaggg gacttctggg aaagggtgga
    13141 aaactgggga ggaatagatg gggatgataa ttaataatta atgtccccaa aaagggaggg
    13201 gaaatggggg tatccccgtt tctttaaccc tttgcactgt ttgcatctgt ttgcagtcct
    13261 ttgcattcgt ttgggtttgt ttgggaggtc tggaagtttc tcgaaacacc attacccatc
    13321 attacccagc ctcccccttt ccttgacaaa cttaaaaaac ccatatacat tagtgaatct
    13381 acaaagcaca gaaaggaaga gactctatgg aaagctccaa cgcggccggt aagccagtcc
    13441 ggaacatacg caaagatacc gttacctggc gtctgttcga gcattacttc ctcatgcagg
    13501 aggcgagtgc ctaccccctc cgtatcccgt gcgagacctg ggggcaggcc ctcaatctca
    13561 gcgtagggtt gaatcgctgt catgtgcagc atcagcgaga aaccgggatg ccggacgagg
    13621 cgatgctgta ctcggccaag ccagtccgta atccagagaa tacggagttc tggatcgagg
    13681 tctcgaccaa ctaccgtagg caagggctgg caagtccgag caagctcgcg cggcaggcgg
    13741 gcgggaactg gatggagaat ctactcgtgc aggcggagag caccctcctt cccgctccaa
    13801 ccccggagag cactcagccg gttccggaca agatggagag tctgctggat accttcatga
    13861 aaggggaggt gaaatgacaa agagtttcgt aatcccgata tgtgtcattc ccgaacatac
    13921 cgtgtatcgc tgtgaagact gcccagattt tgaaaataga ggtggcagct acggtgaata
    13981 tcacgcttgc cttaatatag atcgcgctga tacagacatt caccgccgtg gtggagaagg
    14041 attccccgac aactgccctc gaatcaagaa agaggtgtga aatggactta acaaaccagc
    14101 aagtaacgct gcgtcaggca agaatcgaag aactcgaagc cgaactcgct aaagagcggg
    14161 agaaggggaa gctaaaagaa aaacaaatct ccgatcttct tgcggaggtt gtgttcgagg
    14221 tatcaactcc gcgcattcgc gaactggaag ataaaatcag cgcaatggct ctggaagcac
    14281 tatccgccga agggcaatgg atagaacata ctgctgcaca acaagccacg atagcggaga
    14341 tgaaaaaagc tattgcggca tgggaacgcg ctgaggcggg gcaagagctt caagaagcag
    14401 aagcaaaact gatcgtaata atgaacatcg aaagcaacct cgacgcgctg catgaagcga
    14461 gagcgttgga gtgtgagcgg ttggcggatg ttgcaggcga cgagcccgaa cacgtcaaag
    14521 ccatgttttc agaatggctc cgcgaagaag cagccgccca ccgtgcgcga aaggaagaga
    14581 aatgagcgac tatccaacca gtattaattt gtgtgatggt aagtacacca tcatttatga
    14641 cttcgccacc ggtcagtcag aatgtctgcg ctatgggcaa ccgtggcggc agcttgtggg
    14701 cgacaagatg gtactcgctt gctttgatga aatcgttcga ctccgcgccg a
//
LOCUS       DAOQPD010000095        14360 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_2160_length_14360_cov_23.445369, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000095 DAOQPD010000000
VERSION     DAOQPD010000095.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 14360)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 14360)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14360
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2160_length_14360_cov_23.445369"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..341
                     /locus_tag="PK063_16445"
     CDS             <1..341
                     /locus_tag="PK063_16445"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98692.1"
                     /translation="KQKKDVRMPDEFIQKVVDMPNMEVEVQLCGDDEYFAEKADIVFQ
                     QKGKNIRPVDLSPADRGRKNDGTGPAYRSRFTARFGYESFDPHAKTTIIVTLQDGQTM
                     QFDADFSQVK"
     gene            491..1459
                     /gene="pdhA"
                     /locus_tag="PK063_16450"
     CDS             491..1459
                     /gene="pdhA"
                     /locus_tag="PK063_16450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045250 - cytosolic pyruvate
                     dehydrogenase complex [Evidence IEA];
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HMZ98693.1"
                     /translation="MDRADLFSLYRQMLLIRRFEEKSAEMYALAKIAGFLHLYIGEEA
                     IAVGAIAALRPDDYVISAYRDHGHCLARGSDPGKVMAELFGKATGLCQGKGGSMHLVD
                     LPKRFMGGYAIVGGHIPLAAGLAFASKYQKQDLVTVCFFGEGAVPSGQAHEAFNLAAL
                     WKLPVIFICENNRYGMGTPVQRAVALYENVAEAARSYGITAERVDGMDVLAVRGLMCK
                     VVDQVRAGQGPYFIEAMTYRFMGHSMADPSHGHYRSKEEVEKYRKRDPLVVLKETMVS
                     QAQCSEADFKQLERDIADVVAAAVKFADDSPFPDPASLHADILVED"
     gene            1463..2440
                     /locus_tag="PK063_16455"
     CDS             1463..2440
                     /locus_tag="PK063_16455"
                     /EC_number="1.2.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex E1 component
                     subunit beta"
                     /protein_id="HMZ98694.1"
                     /translation="MLLSYREALNQAMREEMRRDSRIFLIGEEVGYYQGAFKVTKGFV
                     EEFGPQRVVDTPITEAGFTGLAIGAAMAGLHPIVELMTMNFGIVALDQIVNNAAKIRY
                     MSGGQLSVPLVIRGPGSAAHQLGAQHSQSLEAWFCHVPGLKVVAPATPHDAKGLLKSA
                     IRDHNPVIFIEAQLLYGTKGEVGDGEYTIPLGQAEVKREGTDVTIVAYSKMLLVALDA
                     ADQLRREGLDVEVIDPRTLKPLDLETIVTSVTKTGRLVIVEEGWRFCGLGAQIAESIY
                     SAAFDYLDAPIVRVTGEDVPIPYSRPLEDAAIPDVARVIAAVKSLCGAA"
     gene            2504..3703
                     /locus_tag="PK063_16460"
     CDS             2504..3703
                     /locus_tag="PK063_16460"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF012424.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase family
                     protein"
                     /protein_id="HMZ98695.1"
                     /translation="MASRVVMPKLTDTMEEGVLLAWKKHEGDPVHAGEVIAEIETDKA
                     VMDLEAFAPGVLRKVLVHDGETVQSGKLIAVIAEADEDIASALSDGVTAAASTGTGPK
                     SAPSTDAAASVSSGRPRGERVLASPRAKALAAERGVELSTLTGTGPGGRIVEDDVTAA
                     SASVAHALPAGTDQPLSQMRKAIARSTVQSKAPVPHFYLTVDIDMEQAERVRDEFKQS
                     RQPHPSITDVLIKAAALALKRHPEINVSFTGEAIRRYTQIDIGVAVGMDDGLITPVVR
                     NCGGKTLAEISVETKQLIERARHKRLSPQEYTGATFAISNLGMFDVDQFIALLMPPQA
                     ASIAVGAIRDVPVVSRGAVVAGRRMKVTLSCDHRALDGLMGAQFLKEFKRVLEHPEEL
                     LTPVVTP"
     gene            3700..4608
                     /gene="lipA"
                     /locus_tag="PK063_16465"
     CDS             3700..4608
                     /gene="lipA"
                     /locus_tag="PK063_16465"
                     /EC_number="2.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016992 - lipoate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009107 - lipoate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl synthase"
                     /protein_id="HMZ98696.1"
                     /translation="MSFIQIDSRHTAEPQEPSRSQSRRLPPWFKVRLQTGPDYHDIRN
                     TMDRLKLHTICEEARCPNVWECWNARTATFLILGDICTRRCHYCSVATGRPHAVDHEE
                     PLRVAEAIHALNLRHAVITSVNRDELEDGGASVFAETIRHIRRLIPSCTIEVLIPDFE
                     GNEAALAAVAAERPDILNHNIETVRRLFPSIRPQGKYQRSIELLGRAKQMGMTTKSGL
                     IVGMGESTDEAREVMRDLRSVECDIMTIGQYLQPTKEHLAVARFYHPDEFAALKEEGL
                     ALGFRHVESGPLVRSSYHAEQQVSGR"
     gene            complement(4691..5923)
                     /locus_tag="PK063_16470"
     CDS             complement(4691..5923)
                     /locus_tag="PK063_16470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HMZ98697.1"
                     /translation="MSFLWLTIQSALRVLRRNPLRAGLTMLGIIIGVGAVVGMVSLGQ
                     GATASVQREIASLGTNVLIIIPGATTTGGVRGGLGSVSTLTVDDARDIEKRVGDIGLV
                     TYASRSVLQAIHEHKNWNTIAIGTTTAFTDLRNWPVANGSFFTQADEDAAAKVVVLGK
                     TVADNLFERGEEIIGAQIRIKNVPLRVIGVLSSKGQSLSGQDQDDIVILPFTTAERKV
                     LGTKFLGTVGIIMVATQHRYSVPTAVEEITELLRVRHRIHPAEENDFTIRTMEDVAKT
                     VAGASRTMMMMLLSIASISLVVGGIGIMNILLVSVTERTKEIGIRMAVGAKRAHILLQ
                     FLVEAIILTAIGGVAGVVFGILGARLLTHLIGWPTIISSQSIAVAFLFSLAVGIFFGL
                     YPANKASRMNPIEALHYE"
     gene            complement(5934..7253)
                     /locus_tag="PK063_16475"
     CDS             complement(5934..7253)
                     /locus_tag="PK063_16475"
                     /inference="COORDINATES: protein motif:HMM:TIGR01730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HMZ98698.1"
                     /translation="MTSDHSDIDPPRAAHPTPVIVNAVPVVQGQGHGRAPASISQQTL
                     PRHRRRAPIVIGMVGVLTLLAAALWHWWSNDPVNGHYKTVTIDRGPITALVTATGAVN
                     PVISVQVGSQVSGKIAKLYADFNSVVREGQILASIDQKPYQAKVSQAKAALKSAQAGL
                     AKARNMLVQKTLELNRMAALRKEQFVAQADLDLARTNARDAEAQVDVSDAQVDQAKAT
                     LASAELDLGYTTIFSPVNGTVVSRNVEEGQTVVASFQTPTLFVLAQDLTHMQVIANVS
                     ESDIGGVTEGKSADFRVDAYPRESFHGIVTQVRNAPVSIQNVVTYDVIISVDNPDLKL
                     KPGMTANITIVTARNEDALRAPNAALRFRMPGVAVDRKTPQLWVLDASGHVRSVPVSL
                     GIADSLYTDITSSDVHEGESAIVGLATAEDTAQEKLPPGFEFGPKMR"
     gene            7508..8887
                     /locus_tag="PK063_16480"
     CDS             7508..8887
                     /locus_tag="PK063_16480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ98699.1"
                     /translation="MTEEWGAVLVVDDDADMRSLLCDVLQGRGHQCTGVGGGDEALKE
                     LSEEDYAVVLTDLRMKGMQGTELLAEIKQRYPDIGVILMTAFGTVETAVDAMRHGASD
                     YLTKPVKTEELVRVVERAVREASLRREVSRLRKEVHKEYSFHQILGKSKPMQAVFDLI
                     RRVADSPTNVLITGESGTGKELVAKAIHYNSDRRDAPFVPVNCAAIPEQLLESELFGH
                     MRGSFTDAKMDKRGLFEEAQKGTLFLDEISELPLMLQAKLLRAIQEREIRRVGATKSI
                     PVDVRIIAATNLNLVDEVKNKRFREDFYYRLNVIELRLPPLRERREDIPILVDAFLKK
                     CAAARGRQVKGLSEPALAMLADYAWPGNVRELENVIERAVTLSHGDMIGAEDLPIQVQ
                     GARGDRRILDEAAERTLPLHEVEKEYIVKILEKTGGNKYQAAHVLGIDRKTLYRKLAE
                     IEGKPHSDA"
     gene            8924..11605
                     /locus_tag="PK063_16485"
     CDS             8924..11605
                     /locus_tag="PK063_16485"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ98700.1"
                     /translation="MYPLSQKSLLLEYVGPALLTLGIFLLDLSVSAEYTVWLLYAIPL
                     ALTAANSRPGASLYGAGLVSLLVVIGGVASPTGVLPVSFWVNRFLGIGFMAAISFLFA
                     NRRNHSVPTVPPTMPEPAHKESTPTETVGAIAHAEAAVEGAVAGQRRAEAELHRDKLR
                     FEGIVQSAMDAIITVDESQKIVLFNQAAENMFQWSAEDMLGRPLDRLMPERFRSAHAE
                     HIREFGRSGITTRQMGALGVIMGIRSTGEEFPIEAAISQIGVAGTRYYTVILRDITVR
                     KRLEQELAEREALLRAIIETEPECVKVLALDGTVRTMNAAGLAMIEAASNAEIVGKDI
                     CHLVAVESRSVFRDIVRKAGEGEAGRLEFRIVGLQGTPRWLDTHVVPLRAPDGSITAV
                     LGVTRDVTEWKKAEQLLRQSEERYRRLLGVLPDAVLVVRDNRVFFANEQGLRLFGATR
                     AEDLQGKWIYDLIHRDYHEAVAERFRHLLAGGGAVPEAEERILRLDGAMVDVAVRAAQ
                     FRDEDGAGILVVLRDTTMRNVGQQRLKESEERLQSLLESMEDVIWSSSLDLTTLHYVS
                     PSVGQIYGRAAEEFVARPSLWMEVVHAEDRALAEQALRDLQAIGEYDVEYRILRRDGE
                     VRWVHDRGRIIKDETGHPVRIDGIASDITERKRLQAQLRRTERVAELGTVASGMAHEI
                     GTPMNVILGRAEYLMERSKEESVKKGLQTIISQVERITRVMNQLLAFARRRPVEHRAL
                     DLRQTIEDNLEIFQERLSHSHITVETSFADDCPCVHADADQMSQVLINLVMNAIHAMP
                     EGGTLRVMLAPMPDRGMVTLTVADTGHGMPQEVIAKIFDPFFTTKEFGKGTGLGLTVV
                     RGIIEEHSGTIQVESQPGAGTQFTIRLPIHVEPSRKS"
     gene            11863..12267
                     /locus_tag="PK063_16490"
     CDS             11863..12267
                     /locus_tag="PK063_16490"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ98701.1"
                     /translation="MNETTPAVLLVVEDDKDMRSLLCDELWGEGYQLREASNGVEGLE
                     AVMRAAPDLIVTDLKMPSGGFDYVHRLRDCVPACPIIVMTAFGDARTKEEAMKSGATA
                     YFDKPVRLSELKATVKRLLHRSDSLPEEPSFH"
     gene            12410..13813
                     /locus_tag="PK063_16495"
     CDS             12410..13813
                     /locus_tag="PK063_16495"
                     /inference="COORDINATES: protein motif:HMM:NF025885.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ98702.1"
                     /translation="MAGSHAPATPLSPFADPILAARLEALRQLADGLTDRVAVMDRDL
                     NVVYANDAAWGKSGKPPAGVKPAKCYESFVQKQDPCGTCPAESVFVTGEVLTVSCNTS
                     GDGTACGMHQAFPLISSAGEVGSILVLFHKRSDPPAIPAALPQGKLGASRPERTDSRL
                     GDLVGASPAMNQLFEMIRLVADSSATVLIQGESGTGKELVARTIHQTSYRRDKPFVVV
                     DCGALPETLLESELFGHVKGAFTGAAGAKPGLFEEADGGTIFLDEIADTSPTFQAKLL
                     RVLQEGEIKRVGGTQPIKIDVRVISATNKDLTDLVKAKAFRQDLYYRLAVLPVHLPPL
                     RERRADIPLLVTKFIADSCHRHRQELRQVSEEAMRALTAAPWPGNVRELQHYIERAVV
                     TTTHSELTCTDLVSLKFHLEPADLRTVGREAAKQAERARILQALQQTAGNRMKAARVL
                     KISRASLYNKLHDFGIQ"
BASE COUNT         2943 a         3891 c         4537 g         2989 t
ORIGIN      
        1 aaaaacagaa aaaagatgtg cgcatgcccg acgagtttat ccagaaagtc gtggacatgc
       61 cgaacatgga agtggaagtg cagttgtgcg gcgatgatga atactttgcc gagaaggctg
      121 acatcgtctt tcagcaaaag ggtaaaaata ttcgcccggt ggatctcagc ccagctgatc
      181 gaggcagaaa aaacgatggc acgggcccgg cctaccggtc gcgtttcacc gcccggttcg
      241 ggtacgagtc gtttgaccct catgctaaaa ccaccatcat tgtgaccttg caggatggtc
      301 agaccatgca gttcgatgcc gacttttcgc aggtgaaata atcctcagct tccggtgcgg
      361 gtctgcagac ccgtaccggt cacttgcgcg ccccctccct tctcagtgtt gttctttcat
      421 tcgtgcgatg gtgctgacaa ccgaacatca cggttgagtc gtcttgtcgc cggcatgcat
      481 aatgacggac atggacaggg ccgatctgtt ttccctctat cgccagatgt tgctcatccg
      541 tcggtttgaa gaaaagtcgg cggagatgta tgcactcgcc aagattgccg gatttctgca
      601 tctctacatc ggagaagagg cgattgctgt cggtgccatc gctgcgctca gaccggacga
      661 ttatgtcatc agtgcctatc gcgaccacgg acactgtctg gcgcgtgggt ctgatccggg
      721 caaggtgatg gccgaactgt tcggcaaggc aaccggattg tgtcagggca agggggggtc
      781 gatgcatttg gtggatctcc cgaagcgttt tatgggcggt tacgccatcg tgggcggcca
      841 tattccgctg gcggcggggt tggcctttgc ctcgaagtac cagaagcagg acctggtgac
      901 agtctgtttc ttcggggaag gtgcggtgcc gagcggccag gcgcatgaag cgtttaatct
      961 cgcggcccta tggaaactgc cagtgatttt catttgtgag aacaatcgat atggcatggg
     1021 cacgccggtg caacgggccg tggccttgta tgagaatgtg gcggaagccg cgcgttccta
     1081 tgggattacg gctgagcgcg tcgatggcat ggatgtgttg gccgtgcgtg gtttgatgtg
     1141 caaggtggtg gatcaggttc gagcagggca gggaccgtat ttcattgaag ccatgacgta
     1201 tcggttcatg gggcactcga tggccgatcc gtcccatggc cactaccgga gcaaagagga
     1261 agtggaaaaa tatcgcaagc gcgatccgct ggtcgtcttg aaagagacca tggtgagtca
     1321 ggcgcaatgt agcgaggccg acttcaagca actcgagcgg gatatcgctg acgtggtggc
     1381 ggctgcggtg aaatttgcgg acgacagccc gttcccggat cctgcgagcc tgcatgccga
     1441 tatattggtg gaagactaat ccatgctgct gtcttaccgg gaagccctca atcaggccat
     1501 gcgggaagag atgcggcggg actcgcgtat ctttttgatc ggcgaagaag tcgggtatta
     1561 ccaaggcgcc ttcaaggtca ccaagggatt cgtggaggaa ttcgggccgc agcgggtggt
     1621 ggatacaccc attaccgagg ccgggtttac cgggctggca atcggcgcgg ccatggcggg
     1681 tctccatccg atcgtcgagc tgatgacgat gaatttcggc attgtcgcgc tagatcagat
     1741 cgtgaataac gcggccaaga ttcggtatat gtccggcggt cagctctcgg tgccgctggt
     1801 gattcgcggg ccgggcagcg cggcgcatca gttgggagcg cagcactcac agagtttaga
     1861 ggcgtggttc tgtcacgtgc cgggcttgaa ggtggtcgct ccggccacgc cgcacgatgc
     1921 gaagggtttg ctgaagagcg cgattcgcga tcacaacccg gtgatcttca ttgaggctca
     1981 actgctctat ggcacaaagg gtgaggtcgg cgatggtgag tacaccatcc ccctcggcca
     2041 ggctgaggtg aagcgagaag gcaccgatgt gaccatcgtg gcctattcaa aaatgttgct
     2101 ggtggcgttg gacgcagccg accagttacg ccgtgaaggt ctcgatgtgg aggtcatcga
     2161 tccccgtacg ctcaagcccc tcgaccttga gaccatcgtc acctcggtca ccaagacagg
     2221 gcggctggtg atcgtggagg aagggtggcg gttctgtggg ctcggggcgc aaattgctga
     2281 gagcatctac agcgcggcgt tcgattattt ggatgcgccg attgttcggg tcaccggaga
     2341 ggacgtgccg atcccttaca gccggccgtt ggaggatgcc gccattccgg acgtggcgcg
     2401 agtcatcgca gccgtcaaat cactatgtgg tgccgcatga ggcatggttg ccgaaggaga
     2461 caggccggtc gtccaagacc gtccgcttcg tggaggagaa tacatggcta gccgcgtcgt
     2521 catgccgaag ctgaccgaca ccatggagga aggcgttctg ctcgcctgga aaaaacatga
     2581 gggtgatccg gtgcacgcgg gcgaagtgat cgccgagatt gaaaccgaca aggccgtcat
     2641 ggatctggaa gccttcgctc ccggcgtctt gcggaaagtc ctggtgcatg atggcgaaac
     2701 cgtgcaatcg ggcaagctga tcgccgtcat cgcggaagct gatgaagaca ttgcttcggc
     2761 cttgtcggat ggcgtgacgg ctgcagcatc gaccggtact ggaccaaagt ccgcaccctc
     2821 cacagacgcc gccgcatctg tgtcgtcagg tcgccctcga ggagaacggg tgctggcctc
     2881 tccgcgtgcg aaagctctgg cggctgaacg gggtgttgag ctctcgaccc tcaccggcac
     2941 cggtccgggt ggccgcattg tcgaagacga tgtgaccgcc gcatccgcct cggtcgccca
     3001 tgccttgccc gccgggacag atcagccgct gagtcagatg cgcaaggcca ttgccagatc
     3061 gacggtgcaa agcaaggctc cggttccgca tttttatctc acggtcgaca tcgatatgga
     3121 acaggccgaa cgggtgcgcg acgagtttaa gcagagccgt cagccccatc cgtcgatcac
     3181 cgacgtgctc atcaaggctg cggcattggc gctcaagcgg catccggaga tcaacgtctc
     3241 gtttacgggt gaggccatcc ggcggtatac ccagatcgat atcggcgtgg cggtcggtat
     3301 ggacgatggc ttgatcacgc cggtcgtgag aaattgcggg gggaagacgt tggccgaaat
     3361 ttctgtagag acgaagcagt tgatcgagcg agccaggcac aagcgattgt cgccgcagga
     3421 atacacgggg gcgacctttg ccatctccaa tctgggcatg ttcgacgtgg atcagtttat
     3481 cgcgctgctc atgccgccgc aggcggcttc catcgcggtg ggcgcgatcc gcgatgtgcc
     3541 ggtcgtgtcc aggggagctg tggtcgccgg acggcggatg aaggtcacgc tctcgtgtga
     3601 tcaccgtgcg ttggacggac tgatgggcgc gcagttcctc aaagagttta agcgagtgct
     3661 ggagcatccg gaggaattgc tcacgccggt ggtgacgcca tgagcttcat tcaaatcgat
     3721 tcacgccaca ccgctgagcc gcaggagccg tcacggtcgc aatcccgccg cctgccccct
     3781 tggttcaaag tccggctgca aaccggtccg gactatcatg atattcgcaa caccatggat
     3841 cggctcaagc tgcacaccat ctgcgaagag gcgcgctgcc cgaatgtgtg ggaatgttgg
     3901 aacgcgcgga ccgcgacatt tctcattctc ggcgacatct gcacgcgacg ctgccactac
     3961 tgctctgtgg ccaccgggcg gccgcatgcc gtcgatcacg aggaaccgct gcgcgtggca
     4021 gaagcgattc acgcgctcaa tttgcgccat gccgtcatca cctcggtcaa tcgcgacgaa
     4081 cttgaggatg gcggggcatc ggtctttgcg gagacgatcc gccatatccg gcggttgata
     4141 cccagttgca cgattgaggt cctcattccc gacttcgaag gcaatgaggc ggcgttggcg
     4201 gcggtggcgg ctgaacggcc ggatatcctg aaccacaata ttgaaacggt gagacggctg
     4261 ttcccatcga ttcggcccca aggcaaatat cagcggtcaa tcgagttgct gggacgagcc
     4321 aaacagatgg ggatgacgac caagtcggga ttgatcgtcg gcatgggcga atcgacggac
     4381 gaagcccgcg aggtcatgcg tgacctccgt tcagtggagt gcgacatcat gaccattggc
     4441 caatatctcc aaccgaccaa agagcatctc gccgtcgcgc gcttttacca tcccgacgaa
     4501 ttcgctgcgt tgaaggaaga aggccttgcc ctcggcttcc gccacgttga atctggcccg
     4561 ctggttcgta gttcctacca cgccgaacaa caagtgtcag gacgttaaaa aatctccggc
     4621 tcttcctttg tcccagacgg cccagcctac aaccgtgtcg aacagtctgc catctcgttg
     4681 tgagctgccc ctattcatag tgcagcgctt cgatcggatt catcctcgag gccttgttgg
     4741 ccggatagag gccgaaaaag atgccgacgg ccagtgagaa caggaatgcg accgctatgg
     4801 attgggaaga aatgatggtg ggccagccga tcaggtgtgt caggagacgc gctccgagga
     4861 tgccgaagac aacaccggct acaccaccga tcgcagtgag gatgatcgct tcgaccagaa
     4921 attgcagcag aatgtgcgcg cgtttggctc cgaccgccat gcgaatgccg atctccttcg
     4981 tgcgctccgt caccgatacg agcaggatat tcatgatccc gatgccgccg accaccagcg
     5041 agatggaggc gatgctcagg agcatcatca tcatggtgcg gctcgctccg gccaccgttt
     5101 tagccacgtc ttccatcgtg cggatggtga agtcgttttc ctccgcggga tgaatccgat
     5161 gtctcacgcg cagtagttcg gtaatttcct ccaccgctgt cggaacgctg tagcgatgtt
     5221 gggtggcgac catgatgatg ccgaccgttc ccaggaactt ggtgcccaga acctttcgtt
     5281 ccgcggtggt gaacgggagg atgacgatgt cgtcctggtc ctgccctgag agggattgcc
     5341 cctttgacga gaggacgcca atcacgcgca acgggacgtt cttgatccgg atctgcgcgc
     5401 cgatgatctc ttcaccacgc tcgaacaagt tatccgcgac tgttttcccc aagaccacca
     5461 ccttggcggc ggcgtcttca tcggcctgcg tgaaaaaact gccattggcc accggccaat
     5521 tgcgaaggtc ggtaaaggcg gtcgtcgtgc cgatggcaat cgtgttccag ttcttgtgct
     5581 cgtgaatggc ctgcaacacc gaacgtgagg cataggtgac gaggccgatg tcgccgacgc
     5641 gtttttcaat gtcccgggcg tcgtcgactg tcagtgtcga gacgctgccg agtccgccgc
     5701 gcactccgcc tgtcgtggta gcgccgggga tgatgatcag cacgttcgtg ccgaggctgg
     5761 cgatttcgcg ttgcaccgag gcggtggcgc cctggccgag actcaccatg ccgacgacgg
     5821 cgccgactcc gatgatgatg ccgagcatgg tcaggcctgc gcggagggga ttgcgccgga
     5881 gcacgcggag ggcggactga atcgtcaacc aaagaaaact catgaggaat gtgtcaccgc
     5941 atcttcggcc cgaactcaaa tcccggcggc aatttctcct gagcggtatc ttcggcggtt
     6001 gcgaggccca ctatggcgct ctccccttcg tggacatcgc tcgacgtgat gtctgtatac
     6061 aatgaatccg caatgccgag gctgaccggg accgatcgca cgtgccccga cgcgtccagt
     6121 acccagagct gaggagtttt acgatccacg gctacaccgg gcatgcggaa tcgcagtgcc
     6181 gcgttcggtg cgcggagcgc atcttcattg cgtgcggtca caatggtgat gttggcggtc
     6241 atgcctggtt taagtttgag gtcagggttg tcgacagaaa tgatcacatc gtaggtcacg
     6301 acattctgaa tgctgacggg cgcgtttcgg acctgtgtga cgatgccgtg gaatgattct
     6361 ctgggatagg catcgacccg gaagtccgcg gatttgcctt cagtgacgcc gccgatatcc
     6421 gattcgctga cgttggcaat aacctgcatg tgagtgaggt cctgcgccag gacgaagagc
     6481 gtgggtgttt gaaaactcgc cacaacggtc tgcccttctt cgacattgcg cgagacgacc
     6541 gtgccgttca ccggagaaaa aatagtggtg tacccgaggt ccaattcggc ggacgccagt
     6601 gtggccttgg cctggtcgac ctgcgcatca gacacatcca cctgggcctc ggcgtcgcgc
     6661 gcattggtac gtgccagatc caggtccgct tgggcgacga actgctcctt cctcagcgcg
     6721 gccatgcgat tcagttccaa cgttttttgc acgagcatgt tccgtgcttt ggcgagaccg
     6781 gcctgcgcgc ttttgagcgc ggccttagcc tggctcacct tggcttgata aggtttttga
     6841 tcaatggacg cgaggatctg gccctcgcgc acgaccgagt taaagtcggc atagagtttg
     6901 gcgatctttc ctgagacctg gctgccgacc tgcacggaga taaccggatt gacggctccc
     6961 gttgcggtga cgagtgcggt gatcggcccg cgatcgatcg tcacggtttt gtagtgacca
     7021 ttaaccggat cattggacca ccagtgccag agcgcagcag ccagaagggt gaggacgcct
     7081 accatcccaa tgacaatcgg cgcccgacgg cggtggcgag gaagcgtctg ttggctgatg
     7141 ctcgccgggg cacgaccatg gccttgacct tgcactacgg gaaccgcgtt cacgatgacg
     7201 ggcgtgggat gggcggctcg tggaggatcg atgtccgaat gatctgaggt catgtgttcc
     7261 cttccgtttc tctcggggaa gacgcaagag aagtgccgtt tcgtttccgg ctgaaaaatg
     7321 tgatgagtcg gaactggcgc tgctgagggc cgccggctcg tcatcgatgg tggggcattt
     7381 tgcaacaggt tgctggagga gcctgcggca ggacgcccct tgaccgcata ggattgtggc
     7441 tattagtctg tgcccgcaga tatccgggag gctggtgttg cgagcacatg cgagtgaggg
     7501 acgaggtatg accgaggaat ggggcgcggt attggtggta gatgacgacg ccgacatgcg
     7561 gagtctcctc tgcgatgtgc tgcaggggcg cgggcatcaa tgcacgggcg tcggcggcgg
     7621 cgacgaggcg ctcaaggaat tgagcgagga agattatgcc gtcgtgctca ccgatctgcg
     7681 catgaaaggc atgcaaggca cggaactgct cgcggaaatc aaacagcggt atcctgatat
     7741 cggagtgatc ttgatgacgg ccttcggaac ggtggagacc gcggtggacg cgatgcgcca
     7801 tggggcgagc gactatctca ccaagccggt gaagaccgaa gagttggttc gtgtggtaga
     7861 gcgcgcggtt cgtgaagcat cgcttcggcg cgaggtgagt cgtctgcgga aggaagtgca
     7921 caaggagtac agcttccatc agatcctcgg caagagcaaa ccgatgcagg ccgtcttcga
     7981 tttgattcga cgggtggccg acagtcccac gaacgtgctg atcaccggag agagcggcac
     8041 cgggaaggag ttggtggcca aggcgattca ctacaacagc gaccggcggg atgcgccgtt
     8101 tgtgccggtc aattgcgcgg cgattccgga acagctcctg gaaagcgaat tgttcggcca
     8161 tatgcgaggc tcgttcaccg atgccaagat ggataagcgc ggattattcg aggaagcgca
     8221 gaagggcacg ctgttcctcg atgaaatcag cgagttgccg ctcatgttgc aggcgaagtt
     8281 actgcgggcc attcaagagc gggaaatccg gcgtgtcggc gcgaccaagt ccattcctgt
     8341 cgatgtccgg attattgcgg cgaccaactt gaacctcgtc gatgaagtga agaacaagcg
     8401 attccgtgaa gatttttatt accgactgaa tgtcatcgag ttgcgactgc cgccgttgcg
     8461 ggaacggcgg gaagatattc cgatcctggt cgatgcgttt ttgaagaagt gcgccgccgc
     8521 tcgcggcaga caggtcaagg ggctcagcga gccggccctt gccatgctgg ccgactacgc
     8581 ctggccgggc aatgtccggg aactggagaa tgtcatcgag cgcgcggtga cattgagcca
     8641 tggggacatg atcggcgcgg aagacttgcc cattcaggtt cagggggcgc gaggagatcg
     8701 gcggattctc gacgaagcgg ctgagcgaac cttgccgctc catgaagtgg agaaagaata
     8761 tatcgtgaaa atcctggaga agacgggcgg caataaatat caagccgcgc atgtgctggg
     8821 tatcgatcgc aagaccctct accgcaagct cgccgagatc gagggcaaac cacactcaga
     8881 cgcgtagatt tcacgtctca ccgtcgtgcg gggagccatc gtcgtgtacc ctttgtcgca
     8941 aaaatccctg cttcttgaat atgtcggtcc tgcgctcttg accctcggaa tatttctcct
     9001 ggatctatct gtgtcggccg aatatacggt ctggttgctg tatgcgattc ccctggcgct
     9061 gacggcggca aactcccgac caggcgcgtc cctctatggc gcgggattgg tctcgttgtt
     9121 agtggtgatt ggcggggtcg cgtcacccac gggcgttctg ccggtttcct tttgggtaaa
     9181 tcggttcttg ggcatcgggt tcatggcagc catcagcttc ctgttcgcga accgtcggaa
     9241 tcattccgtg ccgacggttc cgccaactat gcctgagccg gcgcacaagg agtcgacacc
     9301 aaccgagact gtgggggcga tcgcccatgc agaagcggcc gtggagggag cagtggccgg
     9361 acagcgtcgg gccgaagcgg aactgcatcg cgacaaactt cgcttcgaag gaattgtgca
     9421 atcggccatg gatgccatca tcacggtcga tgaaagccag aagatcgtcc tgttcaacca
     9481 ggcggcggag aacatgttcc agtggagcgc ggaagacatg ctggggcggc cgttggaccg
     9541 cctgatgcct gagcggtttc gtagcgcgca tgcggaacat atccgggagt tcggccggtc
     9601 gggcatcacc acgcgccaaa tgggagcatt gggggtgatc atggggattc gctccaccgg
     9661 cgaagagttt cccatcgagg cggccatttc tcaaatcggc gtggcgggga cgcggtacta
     9721 cacggtcatt cttcgcgaca ttacggtacg gaaacggctg gagcaggaat tggcggaacg
     9781 cgaagccctc ctgcgagcca tcatcgaaac ggagccggag tgcgtgaagg tgctagccct
     9841 tgatggcacg gtgcgaacca tgaatgctgc gggactggcc atgattgagg cagccagcaa
     9901 tgcggagatc gtcggcaaag acatctgtca tctggtcgcc gttgaatcgc gaagcgtctt
     9961 tcgggacatt gtccgtaaag ccggggaggg agaggcggga cgtttggaat tccggatcgt
    10021 cggcctccag ggcacgccgc gctggttgga cacccatgtg gtgccccttc gagcacctga
    10081 cggaagcatc acggcggtgt taggggtgac gcgcgatgtc accgaatgga aaaaggccga
    10141 gcaactgctg cgccaaagcg aggaacggta tcggcggctt ctcggggtct tgcctgacgc
    10201 agtcctcgtc gtccgtgata atcgggtgtt cttcgccaac gagcaggggc tacgcttgtt
    10261 cggcgccacc cgggcggagg accttcaggg gaaatggatc tatgacttga ttcaccgcga
    10321 ttatcacgag gcggtcgcgg agcgtttccg gcatctgctc gcagggggtg gcgcagtacc
    10381 ggaggcggag gaacggatcc tgcgcctgga cggagcgatg gtggatgtgg ccgtccgagc
    10441 ggcgcagttt agggatgagg acggagcggg catcctggtg gtgttgcggg acacgacaat
    10501 gcgcaacgtg gggcagcaac gactgaagga aagcgaggaa cggcttcaaa gtttactgga
    10561 atccatggag gatgtgattt ggtcatcttc gttggatttg acgacgttgc actatgtgag
    10621 tccctccgtg gggcagatct atggaagggc ggcggaagaa tttgtcgcca ggccgtcctt
    10681 atggatggag gtcgtgcatg ccgaggaccg tgcattggct gaacaagcct tgcgggacct
    10741 tcaggctatc ggcgagtacg atgtcgagta ccggatcctg aggcgggacg gtgaggtgcg
    10801 gtgggtgcat gatcgcggtc gcatcatcaa ggatgaaacc ggtcatcccg tgcggatcga
    10861 tggcatcgcc agcgacatta ctgaacgaaa acggctgcaa gcgcagcttc ggcggaccga
    10921 gcgtgtggcc gaactcggga ccgtcgcatc cggcatggcg cacgagatcg gaaccccgat
    10981 gaacgtcatt ctcggtcggg ccgaatatct catggagcgg agcaaggagg agtcggtcaa
    11041 aaagggacta caaacgatca tcagccaagt cgaacggatc acccgcgtga tgaaccagct
    11101 tctcgctttt gcgcggcggc ggccggtcga acatcgtgcg ctcgacctcc gtcagaccat
    11161 cgaagataat ctggaaattt tccaggaacg cttgtctcac agtcacatta cggtggaaac
    11221 ctcatttgcc gacgattgtc cgtgcgtcca tgcggacgcc gatcagatga gccaggtgct
    11281 gatcaatctg gtcatgaatg ccatccacgc catgccggag gggggaacgt tgcgcgtcat
    11341 gttggcgcct atgccggatc gcggtatggt cacactcacg gttgccgata ccggacacgg
    11401 aatgccgcag gaggtgatcg caaaaatctt cgatcccttc ttcacgacca aggagtttgg
    11461 aaaggggacc ggcttgggtt tgacggtggt cagaggcatt atcgaagagc atagcggaac
    11521 catacaggtg gaaagccagc caggagcagg cacgcagttc accatccgct tgccgattca
    11581 tgtcgagccg agccgcaaat cgtagcccct ctcgttttca actcgattcc cagagcggaa
    11641 ccgcaagcat aacggtcgtc gctgtagcgc ttcggggcaa cctatcggag aatgtggggt
    11701 ctttctcacc aacgctacgg aagcttccct cctgtttgga aatgcctgca ctgcagaagc
    11761 tccaatgaat acaggatctt agcccgtgtc aggtcgacat gcgcatggca tacactttgc
    11821 gatggctgct ttgtcatgag tgtcgcgtac tggagcctca acgtgaacga gacaacccca
    11881 gccgtgctac tggtggtgga agacgataag gacatgcgga gcctgctgtg cgatgagtta
    11941 tggggggaag ggtatcaatt gcgggaagcc agcaacgggg ttgaggggtt ggaggctgtg
    12001 atgcgggccg cgccggatct gatcgtcacg gatctgaaaa tgccctctgg gggcttcgat
    12061 tatgtgcatc gactgagaga ctgcgtccct gcctgtccca tcattgtgat gacggcgttc
    12121 ggggatgcgc ggaccaaaga agaagcgatg aaaagcggcg ccacggccta tttcgacaag
    12181 ccggtgaggc tgtcggaatt aaaggctacg gtgaagcggc ttttgcaccg ttccgactcc
    12241 cttccggagg agccgtcgtt tcactgaata cccgcgccgg acgggcgctt tcggctggtc
    12301 gcccccaacc ggggagggtt gtcttcgacc cataagccgt agtacatata gggccttctc
    12361 tgtgaagaaa ggcccctgct tgattccctc tgatagaagg agtgatgaga tggccggatc
    12421 tcatgcacca gcaacacctc tttctccttt cgccgatccc atccttgccg ctcgtttgga
    12481 agcgttgaga cagttagctg acggcctgac cgaccgcgtt gccgtcatgg accgggatct
    12541 taatgtggtc tatgccaatg atgcggcctg gggaaagtcc gggaagccgc cagcgggagt
    12601 caagccggcc aaatgctatg aatcattcgt tcaaaagcaa gatccttgcg ggacatgccc
    12661 cgctgagtct gtttttgtga cgggtgaagt gctgaccgta tcctgcaata catcaggtga
    12721 tgggactgcc tgtggtatgc accaggcttt tccgcttatt tcctcggcgg gagaggtggg
    12781 ttctattctt gtcttgtttc acaagcggtc tgatccgccg gctattccag cagcgctccc
    12841 ccagggcaag ctgggcgcat cacgcccgga acggacagat tcgagattgg gcgatttagt
    12901 cggtgcgagt ccggcgatga atcagctttt tgagatgatt cggttggtgg ccgacagttc
    12961 ggcgacggtg ttaatccaag gcgaaagcgg cacgggaaaa gagctcgttg ccaggaccat
    13021 ccaccaaacc agctatcgtc gtgacaaacc ctttgtggtg gtggattgcg gtgcactgcc
    13081 ggagaccttg ctggagagtg aactcttcgg ccacgtcaaa ggtgcgttca ccggtgccgc
    13141 cggcgccaag cccggcttgt ttgaagaagc cgacggtgga accattttcc tggatgagat
    13201 tgcggacacg tccccgacat ttcaggcgaa gttgctacgg gttctgcagg aaggcgaaat
    13261 taaacgagtc ggcggtaccc aacccatcaa gatcgacgtc cgtgtcattt cggccaccaa
    13321 taaggatttg accgacctgg tcaaggccaa ggcgttccgc caagatctct actatcgttt
    13381 ggcggtgttg ccggtgcact tgcctccgct acgggaacga cgagcggata ttcccctgct
    13441 ggtgaccaag ttcatcgcgg attcctgcca ccgacatcgc caggagcttc gtcaggtgag
    13501 cgaagaggcc atgcgtgcct tgacggctgc gccctggccg ggaaacgtgc gtgagttaca
    13561 gcactatatc gaacgtgcgg tcgtcaccac gacccattca gagttgacct gtacggacct
    13621 ggtgtcatta aaattccacc tagaacctgc cgatctgcgt acggtcgggc gggaggcggc
    13681 caagcaggcc gaacgcgcca gaattcttca ggcgttgcag cagaccgccg ggaatcgaat
    13741 gaaggccgcc cgtgtcctaa agatcagccg agccagcctc tataacaaac tccacgattt
    13801 cggtatccaa tagagtcagg caactgagtt agctgcccct tctcttcttg gtcacatttc
    13861 ggccattcca acctttcaaa ttcccaacag aatcagcccc atgctcttcg tctacgtgtc
    13921 tcttgatgca tccattgccc cgtatcgcca cagaatcgag cgatctgtcg tctagcgaat
    13981 tggacagtct aagtagttgt aatttcattg ttcatcatcc tgtggcgctc acctgtctaa
    14041 acgtctagaa aaactgtagc gtttcacgcc gcttccgatt gtctgacgag agttcataac
    14101 ctattaataa aactcggtat ttatcgcgtt ccaggggtat ccctagggag ggcacatcaa
    14161 ttgcgatgtt gggcagtgct ggtgaaggtg cgggtgatta ggaccggcct ccgaatgacc
    14221 tgctccctcg aactttgagg acatccttca ccagcccttt ttccctttgg agcgtttcgt
    14281 ggagggagaa aggcgaggcc ggaagagccg gggtcctgcc tgacggaggc cggtcacacg
    14341 accacgtttt ttaaccactc
//
LOCUS       DAOQPD010000096        14352 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_2162_length_14352_cov_20.720781, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000096 DAOQPD010000000
VERSION     DAOQPD010000096.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 14352)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 14352)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14352
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2162_length_14352_cov_20.720781"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..3470
                     /locus_tag="PK063_16500"
     CDS             <1..3470
                     /locus_tag="PK063_16500"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="vitamin B12-dependent ribonucleotide reductase"
                     /protein_id="HMZ98703.1"
                     /translation="EIRNPDGSTVFKLEHIDIPEHWTQLAIDILAQKYFRKAGVPQVH
                     EDGTPVVDAAGKPVLGGERDSRQVFNRLAGCWTFWGKNHGYFKTPEDATAFHDEMCYM
                     LAYQMAAPNSPQWFNTGLHYAYGLSGPAQGHFYVDPKLGEVVRATNAFEHPQPHACFI
                     QSIEDDLVNENGIMDLWVREARLFKYGSGTGTNFSRLRGDGESLSGGGRSSGLMSFLK
                     IGDRAAGAIKSGGTTRRAAKMVCLDLDHPDIEEFIDWKVVEEQKVAAMVTGSKICAQR
                     LNAVLKACQSVDAQGQAHLELDMKQNQALREAVTAARRDMVPEAYIHRMFDYAKQGYT
                     HFVFHEYDTNWDGKAYQTVSGQNSNNSVRIPNGFFDALEHDGDWELRRRIDGKISKTI
                     KARDLWDKIAWAAWICADPGTQYDTTINEWHTCPEDGRINASNPCSEYMFLDDTACNL
                     ASLNLAKFFNAEGEFDLDSFRHAVRLWTVALEISVLMASFPSRAIAQKSYDYRTLGLG
                     YANLGTILMKQSIPYDSQKATAICGAITAIMTGESYATSAEMAAEIGPFPGYNRNRES
                     MLRVIRNHRRAAYSAPHEEYEGLTILPASIQPEHCPPAMLLAARRAWDRALELGTAYG
                     FRNAQVTVIAPTGTIGLVMDCDTTGIEPDFALVKFKKLAGGGYFKIINQSLPPALQAL
                     GYTEAQIRDIVAYCAGHQTLKGAPFINHEVLRQKGFDEAALERLEGSLAQAFEIQFVF
                     NKYTLGEEFCRQKLGISEAQLADPAFNMLKTLGFTQEDVAAANDYCCGTMTVEGAPHL
                     KLEHLPIFDCANRCGRIGQRYIAVDAHIRMMAAAQPFISGAISKTINMPADATLEDVK
                     AAYLFAWKSMVKAVALYRDGSKLSQPLNASSDSGKSAEAAPSVATVAEKVAERVLVRY
                     LHKRRSLPARRGGYTQKAIIGGHKLYLRTGEYEDGTLGEIFLDMHKEGAAFRSLMNNF
                     AIAISLGLQHGVPLEEFVEAFVFTRFEPNGPVKLNDRIKMATSIIDYIFRELAITYLE
                     RKDLSQVQEDDLRMDSMKKDEQDPECVEEEVDMTALKKASILTEHLPVRRNGMNGGNG
                     HTQRAGNGSVAHKLELKRETLTVTSVRQEAKEKGYEGDPCQNCKQFTLVRNGTCLKCM
                     SCGETSGCS"
     gene            3725..4090
                     /locus_tag="PK063_16505"
     CDS             3725..4090
                     /locus_tag="PK063_16505"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ98704.1"
                     /translation="MKKRYSSRASVQSTCVLSCNGLVGQAEMVNLSVPGCLLTTRMKL
                     KVGQYVDLRLTFHTSPAPMQIKLAAVRWVSDGQVGLEFIRMSEADQTRLRWLAGHVEQ
                     RKPQANWSEPVVCLSAAYT"
     gene            4470..4700
                     /locus_tag="PK063_16510"
     CDS             4470..4700
                     /locus_tag="PK063_16510"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98705.1"
                     /translation="MMLRSIRKEVLEFAKVTERLLGAASLTHELTEEECTLIALYAKD
                     LSADQQPWSKFIPGTQHQDPAYPSKGMWESSA"
     assembly_gap    5500..5599
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <5600..6826
                     /locus_tag="PK063_16515"
     CDS             <5600..6826
                     /locus_tag="PK063_16515"
                     /inference="COORDINATES: protein motif:HMM:NF017197.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF748 domain-containing protein"
                     /protein_id="HMZ98706.1"
                     /translation="VTRPQAKTELKETRPSGWQDIVRNLLPLRVSDVKIKQAQVTYYD
                     HPKAQPVKLTDLQFEAREISNRGGEGQEYPSTIKMEARLPQGGRITAEGHANALAKPL
                     PAFNVDFSLDDIALRDFVGLAGGYNVQLDRGKITANGHAEYAPWKQVADVREIRLEGV
                     KADYVYRRHPRDEARREEAVAVAKKAKDNPLLVINVKQGKILDSEFGFVNQSVTPHYR
                     VFVGEVNADLDNFTTRLRELQGGDAVIKVTGRFMGTGRSVIVGTFRPEKPSPDFDVGV
                     QIVKTELKSFNDVLRAYGDFDVHRGNLSVFSELSIRHNQVSGYLKPIFKDVEAYDPNQ
                     DADKAWTKKVFESVIDGIVKLLNNTSEDQVAADAGISGPVKNPSADTWQVMGTLIQNA
                     FFKAILPGLEKEHGKA"
     assembly_gap    6890..6989
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <6990..7747
                     /locus_tag="PK063_16520"
     CDS             <6990..7747
                     /locus_tag="PK063_16520"
                     /inference="COORDINATES: protein motif:HMM:NF013215.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98707.1"
                     /translation="LLPRIRQRIERDLALPGLPREKILATVVRLLETTLIRVGNEEYA
                     KTNNSFGLTTMRDRHARVEGARVRFEFRGKSGVQHLVDLTDRRLARIVRQSQDLPGYE
                     LFQYVDAEGARHGIDAGDVNDYLRHIAGEECTAKDFRTWAGTVLAAKALQECRAIGSA
                     AQAKRNIVAAIEVVAKRLGNTKTICRKCYVHPEIVQAYLEGSLARSLTTRIRRPFARM
                     AGCLTPDEAAVLACLERRLGRKASRGIGLRSSA"
     gene            complement(8095..8595)
                     /locus_tag="PK063_16525"
     CDS             complement(8095..8595)
                     /locus_tag="PK063_16525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014961780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HMZ98708.1"
                     /translation="MLWLFPTHGSVGMFIVRVTLAIVIFAHGAQKLLGWFGGQGFTGT
                     IGFFTTSMGLPWLIAFLVIIGESIGSLSLLAGFLTRFVAASYLLIMLGAVAMVHWPNG
                     FFMNWFGQQQGEGFEYHLLIIGMSVALLLEGGGAWSVDHLIARWMAQHGWAGTQPLHA
                     FAQSKQ"
     gene            complement(8832..9146)
                     /locus_tag="PK063_16530"
     CDS             complement(8832..9146)
                     /locus_tag="PK063_16530"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98709.1"
                     /translation="MMDTVHTISNEQPTYEESVRLGWALLWRGVGSFVLLMFAGNIGL
                     LFLIPELTRTVPTLWIALLPLAFATLISAFLIMPFVVRRLVKAPFKGFHLSFVRDRLL
                     GQ"
     assembly_gap    9434..9533
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <9534..9975
                     /locus_tag="PK063_16535"
     CDS             <9534..9975
                     /locus_tag="PK063_16535"
                     /inference="COORDINATES: protein motif:HMM:NF012422.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ98710.1"
                     /translation="DLLEHIRSLHPSTPVLVYSMHSEESYAVRMIRSGASGYLNKSTG
                     LDELVAAMRSILAGQEFINPAVARCLIERMRTKDSGQLHDALSNREFQILRMVAQGES
                     LKQIALTLCVSANTVSTYRTRILQKLRLKTNAELTRYALEHALI"
     gene            complement(10210..10512)
                     /locus_tag="PK063_16540"
     CDS             complement(10210..10512)
                     /locus_tag="PK063_16540"
                     /inference="COORDINATES: protein motif:HMM:NF012305.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HMZ98711.1"
                     /translation="MHTPCDLSLLIDGLSSTVTRADIVALFSSCGTVTAAEIVIDADG
                     MPLGVARVTMSTKEEARFAIRTFHRCQFRGHTLLVFEDVTKNQREDLWNSRMFKRP"
     gene            complement(10896..12161)
                     /locus_tag="PK063_16545"
     CDS             complement(10896..12161)
                     /locus_tag="PK063_16545"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ98712.1"
                     /translation="MPTSGAQIERLRRKAEAYLRESAHTPPIDQSATETAQLVHELRV
                     HHVALRLQCEELRQTHLELEESRNRYVELYESIPVGYFSLNPRGAICDVNPAGAAMLH
                     QPMNRLIGRRFHLFMPVAQRRRFIEFCKQVCFERKRLSCEVDLGDASDDQPRALMNVL
                     LEGSPAQGQKDIMRLAVIDITRRKEAEQQLKVQEDELRTSRQKLQDLNAQLLNIQDEE
                     RRAIARELHDNCCQQLAMMMFSVNSIERCCDEPLTHKVRMLNEQIKRTLESVRHIAYG
                     LHPAMWDTMGVEEAMRSYLKDFIEVTELPVDFHAIDVPRRVPEVISTCLFRTLQEMLH
                     NVVKYAQASRVEVRLIKNENTLSLYVTDHGRGFHVKTMKQSPRGLGLVSLKERAQLLN
                     GTLNVTSQIGVGTMVHVILPLTSGNDHPM"
     gene            12523..13527
                     /locus_tag="PK063_16550"
     CDS             12523..13527
                     /locus_tag="PK063_16550"
                     /inference="COORDINATES: protein motif:HMM:NF024583.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HMZ98713.1"
                     /translation="MPATLVLERWAANWKMGSDVVPGAARLLWNATKQHAILGQILIM
                     TCGLAAHMEEALITPNVEHEPCWQPWLWLAREYGYRACWSFPVRTFGGPILGTLAWYF
                     KDPREPSLRMMELAATLTHAAAIIISRHREAEERTRVEAALRESDARYRAFVAVTSDI
                     VYKMSADWSEMQSLVGKEFIASTERPRRDWMDAYIPDADRTVVWEAIGAAIHSKQAFE
                     LEHQVIRLDGTIGWTYSRAVPLFDQKGEIVEWFGTASDITERKQAEAQLKTRNIELER
                     FNKVMVGRELRMMELNHKSPGRQGLQSESPLDQFTIEAQRPAAEPGQGDPGGESPRRA
                     "
     gene            13622..13915
                     /locus_tag="PK063_16555"
     CDS             13622..13915
                     /locus_tag="PK063_16555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HMZ98714.1"
                     /translation="MRMTVDQHVVAAEWQARGFSCDLWVDPPGQVWEDYRHATDEVIM
                     LVAGRLELEFGGRCLTPVPGEEILIPAGVSHTVRNIGGTTVQWLYGYKRVHTG"
     gene            13946..>14352
                     /locus_tag="PK063_16560"
     CDS             13946..>14352
                     /locus_tag="PK063_16560"
                     /inference="COORDINATES: protein motif:HMM:NF040320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98715.1"
                     /translation="MPTTTQFVVSGQSKPGVLASVAAVLGAAGVNIKAFSAPEVTGPG
                     KLRLIVADVDAARIALRKAKVKFREETALILSLENKPGALKQVADSLTRARINVKCGY
                     CTPSREGKRAIVVLTVSNTTKALGVLRTHSLDE"
BASE COUNT         3082 a         3926 c         4175 g         2869 t
ORIGIN      
        1 cggagatccg gaatccagac ggatcgaccg tgttcaagtt ggagcatatc gatatcccgg
       61 aacattggac gcaattggcg atcgatattc tggcgcaaaa atatttccgg aaggccggag
      121 tgccgcaagt gcacgaggac ggcacgccgg tggtggacgc cgcaggcaaa ccggtcttgg
      181 gaggggagcg tgattcccgt caggtgttca accggttggc gggatgctgg accttctggg
      241 gcaagaatca cggctatttc aaaacgccgg aagatgcgac cgccttccac gatgaaatgt
      301 gctacatgct ggcctatcag atggctgccc ccaacagccc gcagtggttc aacacggggt
      361 tgcactatgc ctacgggctt tcagggccgg cgcaaggaca cttctacgtc gatcccaagc
      421 tcggcgaggt cgtgcgggcg accaatgcct tcgagcatcc gcagccgcat gcctgcttca
      481 ttcagtcgat tgaagacgac ctggtcaacg agaacggcat catggacctg tgggttcgtg
      541 aagcacggct cttcaagtac gggtcgggca ccggcacgaa cttttcgcgg ttgcgtggcg
      601 atggtgaatc cctgtcgggc ggcggacgtt cctccggtct gatgtcgttc ctgaaaatcg
      661 gcgaccgcgc tgcgggagcg atcaagtcgg gcggcaccac gaggcgcgcg gccaagatgg
      721 tctgcctgga tctcgatcac cccgatatcg aagaattcat cgactggaaa gtggtcgaag
      781 agcagaaggt ggccgcgatg gtcaccggtt caaagatttg cgcgcagcgg ctcaatgccg
      841 tgctcaaggc ctgtcaatcg gtcgatgcgc agggacaggc tcatctcgaa ttggatatga
      901 agcagaatca ggcgctgcgc gaggccgtga cggcagctcg ccgcgatatg gtgccggagg
      961 cgtatatcca tcgcatgttc gactatgcga agcagggcta tacccacttc gtgtttcacg
     1021 aatatgacac caactgggac ggcaaggcct accagaccgt gtctgggcag aactccaaca
     1081 acagcgtgcg tatcccgaac ggcttcttcg atgcgttgga gcacgacggc gattgggaat
     1141 tgcgccgccg gattgacggc aagatcagca agacgatcaa ggcccgggac ctctgggata
     1201 agatcgcctg ggcggcctgg atttgcgccg atcccggtac gcagtacgat acgacgatca
     1261 acgaatggca tacctgtccg gaagacgggc ggatcaacgc gtcgaatccc tgttccgaat
     1321 acatgtttct cgacgacacg gcctgcaacc tggcctcgtt gaacctcgcc aagtttttta
     1381 acgccgaagg ggagttcgac ctggattctt tccgccatgc cgtccggttg tggaccgtgg
     1441 cgttggagat cagcgtgctg atggcttctt tcccgagccg cgcgatcgcg cagaagagtt
     1501 acgactaccg gacattggga ttggggtatg ccaacctcgg caccattctc atgaaacaaa
     1561 gcattccgta tgactcccag aaggcgacgg caatttgcgg cgcgatcacg gcgatcatga
     1621 ccggcgaatc ctatgcgacg tcggccgaaa tggctgcgga gatcggcccg tttcccggct
     1681 acaaccggaa tcgggagtcg atgctgcgcg tcatccgcaa tcatcggcgg gcggcctaca
     1741 gtgcgccgca tgaggagtat gagggcctga cgattctgcc ggcctcgatt caaccggaac
     1801 attgtccgcc ggccatgctc ctggcggcgc ggcgcgcctg ggatcgggcg ttggagttgg
     1861 gcacggccta cggcttccgc aacgcgcagg tcacggtcat tgcccccacc ggcacgatcg
     1921 ggctggtcat ggattgcgac acgaccggca tcgagccgga cttcgccctg gtcaagttca
     1981 agaaactggc cggcggcggt tacttcaaga ttatcaacca gagtctgccg ccggcgctgc
     2041 aggcgctcgg gtatacggag gcccagatcc gggacatcgt ggcctattgc gcgggccatc
     2101 aaaccttgaa gggcgcgccg ttcatcaacc atgaggtgct gcgtcaaaaa ggtttcgacg
     2161 aggcggcgct ggaacggctg gaaggatcgc tggcgcaggc gtttgagatc cagttcgtct
     2221 tcaacaaata cacgttaggc gaagagttct gccggcagaa actgggcatc agcgaagcgc
     2281 agttggcaga tccggcattc aacatgctca agaccctggg tttcacccag gaagatgtgg
     2341 cggcggcgaa cgactattgc tgcggcacga tgaccgtgga aggcgcgccg catctcaagc
     2401 tggaacattt acccatcttc gattgcgcca accgttgcgg ccggatcggt cagcgctaca
     2461 tcgccgtcga cgcgcatatc cgcatgatgg cggcagccca gcctttcatc agcggcgcga
     2521 tcagcaagac catcaatatg ccggcggacg ccaccttgga agacgtgaag gcagcctacc
     2581 tcttcgcctg gaagagcatg gtcaaggccg tagcgctgta tcgtgacggg tcgaagttga
     2641 gtcagccgtt gaatgcctct tccgacagcg ggaagagcgc ggaggcggcc cccagcgtgg
     2701 ctaccgtcgc ggaaaaggtc gccgaacggg tcttggtgcg gtatctccac aaacgccgtt
     2761 cgctgccggc ccgacgcggc gggtatacgc agaaggccat catcggaggc cacaagttgt
     2821 atctgcgtac cggtgagtat gaagacggca cgctgggcga aatcttcctc gacatgcaca
     2881 aggaaggcgc ggctttccgc agcttgatga ataacttcgc catcgcgatt tccctcggtc
     2941 tgcagcacgg cgtgccgctg gaggagttcg tcgaagcctt cgtcttcacc cggttcgagc
     3001 cgaacgggcc ggtgaaattg aacgatcgca tcaagatggc cacgtcgatc atcgattaca
     3061 ttttccggga actggccatc acctatctcg agcggaaaga tctctcccag gtgcaggaag
     3121 atgatcttcg catggactcc atgaagaagg atgagcagga tcccgaatgc gtggaagaag
     3181 aggtcgacat gacggcgctc aagaaggcgt cgatcctgac tgagcatctg cccgtgcgac
     3241 ggaacggcat gaacggcggc aatggtcata cccagagagc ggggaatggc agcgttgccc
     3301 acaaattgga attaaagcgt gaaaccctga ccgtgacctc ggtgcggcag gaagccaaag
     3361 aaaagggata cgaaggcgac ccctgccaga attgcaaaca gttcacgctg gtgcgcaacg
     3421 gcacctgcct caagtgcatg agctgcggcg aaacgagcgg gtgctcatag cgtagatcga
     3481 ccacgggtta gcagaacagc aaggccgcga ttaccgttga aaaacgaggt agtcgcggcc
     3541 ttttcttgca gccggttcat ttttgtcctt tccgccgact cgctgccgga gctagtcaaa
     3601 cagcattcag tacctggcat tccccccctt tcgagttacc aacaccaggt aatgtgcccg
     3661 ggactttcct cggctaactt taagtcatca acgacgtcgg cggcccacac ccagaggagg
     3721 acggatgaaa aagcgataca gttcacgagc gtcagtgcag agcacctgcg tgttgtcctg
     3781 taacggctta gtcggccagg cggaaatggt caacctctcc gtgccgggct gcctgctcac
     3841 cacgcgtatg aaactcaagg tcggtcagta cgtggacctg cggctcacgt tccataccag
     3901 ccccgcacct atgcagatca agttggctgc tgtgcgttgg gtcagtgacg ggcaggtggg
     3961 gctggagttc atccggatgt cggaggcgga tcagacgcga ttgcgctggc tggcaggcca
     4021 tgtcgagcag cgaaaacccc aagccaactg gagtgagcct gtggtctgtc tgagtgccgc
     4081 ctatacctaa acctcatcga agggacggga gcgacgcaag aacgggcagc agaacattgt
     4141 tgcccgttca cctcctcatt ccgtcgatga ggtccaagtt gtgcgaatca ccgcacgagg
     4201 cgcatgtctt ccggcacatc attcatcgcg aaatgaacct gcataagtat ctgcgtcacg
     4261 cgtgcttaaa ccaattccat cgttgtttcc atatggctct tcgatgatgg gatgctcgtt
     4321 tttcactcgc cctagtcgaa attgaatgcg cggtcttggt cgcggtaagc ggtcttctac
     4381 gtaataggtt tgtgcaattg tcaacagggg gcgcttgccg tatcgtggct cctacgtcgt
     4441 tggacaaaag gcttcaaccg ggggacgcga tgatgcttcg ttctatccgc aaagaagtcc
     4501 tcgaattcgc gaaagtgact gaacgtctcc tgggcgccgc atccctcact catgaattaa
     4561 ccgaggagga atgcacactg atcgcgcttt acgccaaaga cttgagtgca gatcagcaac
     4621 cctggagcaa attcattcct ggcactcagc atcaagatcc agcctatcca tccaagggta
     4681 tgtgggagag cagcgcatag cggtcaatgg caatgtgagt gagatccatg tccggagaat
     4741 tcattctgca gaaaggagag cgtatgcaac ccctaccgcc acagcctccc gtcggatcac
     4801 ccataacgcc tcctccctct cccgctcatc tccaatgctc ctactgtgca accgcaatgc
     4861 tgtttctcgg ctacacgcca agcgagcaat gtgcggaatg gatttgtccc aagtgtagga
     4921 tgatgaagat tcgcccgctg gcgatgctgg cgacgatctt ggacagttcc acaaccgcga
     4981 gatctgtctt gcctgatccg acgcgagtcg gtccaaacgc ccagtgactg aattgcggtt
     5041 gccgactcac tctacggtga ggggcaaccg ctttctcgtt gcctgggcct atgatcaaaa
     5101 agatcccacc gtttcattgc ggcgatgacg ggaacttcac tctaatcttt ccccaaatca
     5161 tcttctcagg tcgcgccaac tccaggtagg tcatgtgagg cgcgagtaca caccaccgta
     5221 cccggctgtt caggcgaaga ttcgctgtcg atcgcgtcac cctgtaccgt tgggcacaat
     5281 agcttccgac tgcatagtac tagggttcat ccgagttgga cgattgtgcc ggtctgctac
     5341 cgtgtgtgtg gtccgcacgt taaacatgag agaggtaagg ttgtgtttac tccccctcac
     5401 atctcccgct ggatgaagtg ggtcggcggt attgttgttg tcctggtgac ggcgatgctc
     5461 ctcgtcgcag ttatcgcgga tgagccggcg cggaagtatn nnnnnnnnnn nnnnnnnnnn
     5521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5581 nnnnnnnnnn nnnnnnnnng tgacgcgccc ccaagccaag acagaactca aggaaacccg
     5641 tccgagcggc tggcaggaca tcgttcgcaa ccttcttccc cttcgagtca gtgatgtgaa
     5701 gatcaagcag gcccaggtca catactacga tcatcccaaa gctcagccgg tgaaactcac
     5761 cgacctgcag tttgaagcaa gggagatcag caaccgcggc ggcgaaggtc aggaatatcc
     5821 ttccaccatc aaaatggagg cacggctgcc acaggggggc cgcattaccg ctgagggcca
     5881 tgccaatgct cttgccaaac cgctaccggc tttcaatgtg gacttcagtc ttgacgatat
     5941 cgcgctgcgg gatttcgtcg ggctcgcggg tggctacaac gtgcaactcg accgaggcaa
     6001 gatcaccgcg aacggccatg ccgaatatgc gccctggaag caagtggcgg atgtgcggga
     6061 gatccgtctg gaaggggtga aggccgacta tgtctaccgg cgacatccaa gagatgaggc
     6121 gcgccgggag gaagccgtgg cggtcgccaa gaaagcgaaa gacaatcctc ttctcgtcat
     6181 caatgtgaag cagggcaaga tcttggatag cgagttcggc ttcgtgaatc agtccgtgac
     6241 ccctcattac cgggtgtttg tcggcgaggt caatgcagac ctggacaatt tcacgaccag
     6301 gctgcgggag ttgcaagggg gcgatgcggt catcaaagtg acgggacggt ttatggggac
     6361 ggggcggagc gtcattgtgg gcaccttccg gcctgaaaaa ccctcccctg atttcgatgt
     6421 cggagtccaa atcgtgaaaa ccgaattgaa atcgttcaac gatgtgctcc gagcctacgg
     6481 cgacttcgat gtccatcgag gcaacctttc cgtcttcagt gaactgtcca tccgccacaa
     6541 ccaggtctcc gggtacctca aaccgatctt taaagatgtc gaagcctatg accccaacca
     6601 ggatgccgat aaagcgtgga caaaaaaagt gttcgaatcc gtcatcgacg gcatcgtgaa
     6661 actgctgaat aacacaagcg aggatcaggt tgcggccgac gccggtatat cgggccccgt
     6721 gaaaaatcct tctgccgaca cgtggcaggt gatggggact ttgatccaaa acgccttctt
     6781 caaagccatt ctccctggct tggaaaaaga acacggcaaa gcttgacccg catgcaatcc
     6841 atggcgcctc cacagtcacc gttatgatga gaatgatcgc tgccaaggan nnnnnnnnnn
     6901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnng gctgttgccg cgcatccggc aacgcatcga
     7021 gcgggacctt gccttgccgg gtttgccacg agaaaagatt ttagccacag tcgtacgcct
     7081 gctcgaaacc acgctgatca gagtcggcaa tgaggaatat gccaaaacca ataattcgtt
     7141 cggactgacc acgatgcgtg atcgccacgc ccgcgtcgaa ggggcaagag tccgattcga
     7201 gtttcgaggc aagagcggtg tgcaacatct ggtggatctg acggaccgcc ggttggcccg
     7261 catcgtgcga caaagccagg atctgccggg atacgaactc tttcaatacg tcgatgcgga
     7321 gggcgcccga catggcatag atgcgggaga cgtcaatgat tatctccggc acatagccgg
     7381 ggaggagtgt acggcgaagg actttcgcac ctgggccggg accgtgctgg ccgcgaaggc
     7441 gttgcaagaa tgccgcgcca tcggatcggc agcgcaggcg aaacgcaata tcgtggctgc
     7501 catcgaggtg gttgcgaagc ggctgggcaa taccaagacc atctgccgga aatgttatgt
     7561 gcatccggaa atcgtgcagg cctacttgga aggatcgttg gctcgatcct tgacgacgag
     7621 aatccggcga cctttcgcac gcatggcggg atgtctcacg ccagatgagg cggcggtact
     7681 agcgtgtctt gagcgccgcc tcgggcgcaa ggccagtcgg ggcataggat tgcgctcatc
     7741 ggcataaggg agaggaggat gcgtgtcccg gccgtgcatc cggccccatt gatgtgtacc
     7801 aagatctttg caacggagcc gcattcgtca gagaaggcgt aggcgcattg gataaatcaa
     7861 atgtcagggt atatggcggt gacttgtata cgatgtggga gattccagat ctgccacagt
     7921 gctcatgcgc gcatgggctc gtcattagcc tggtcctgcg aggggctccg ctgtcttacc
     7981 tgcggatcgc tcgcagacat tccagggtgg ggcgagcagg acgtctctga tcggggcggc
     8041 atacctccga cacctgctca cgggtctctt tcgcctgttc agccgtgggg ctggttattg
     8101 tttgctctgg gcaaaggcat gtaatggctg agtcccggcc catccatgtt gggccatcca
     8161 cctggcgatc aggtggtcga cagaccaggc cccgccacct tccagaagaa gtgccacact
     8221 catcccgatg atcaacaggt gatattcaaa tccctcgccc tgctgttgcc caaaccaatt
     8281 catgaagaag ccgtttggcc agtgcaccat ggcaacagct cccagcatga tgagcaggta
     8341 gctggcagcc acaaagcgag tgaggaaccc ggccagcaga ctgaggctgc cgatcgactc
     8401 gccgatgatg acgagaaagg ctatgagcca gggaaggccc atggaagtgg taaaaaatcc
     8461 aatcgtgccc gtaaagccct gtcccccaaa ccagcccagg agtttctgtg ccccatgggc
     8521 aaagatcaca atcgccaggg tcacacgcac gatgaacatt cccacagagc cgtgagtggg
     8581 gaagagccag agcatgggtg acctccacat tggggattgc atgtcgccgg tgtcgggcca
     8641 ttttcatcta tggcgttgaa atcactctgg gttgccggtt caagcccgtc gcgctgctgg
     8701 aagtagatcg acgtctggct gtatcgacgc actgccagcc gctggactcc ttcctagatg
     8761 ttaagcggcc ttgagttcgt tgtgccgccg cttgttggga acagcgagga agaccaatcc
     8821 atcctctcga gttactgacc gagaagtcga tctcgtacga agctcaggtg gaaccccttg
     8881 aatggcgcct tcaccaatcg ccggacaaca aacggcatga tgagaaaggc actgatcaaa
     8941 gtggcaaagg ccaggggcaa cagggcaatc catagtgtcg gaactgtccg cgtcaattca
     9001 ggaatgagaa agagcaagcc gatgtttccg gcgaacatga ggagaacgaa gctacccact
     9061 ccgcgccaca gcagggccca gccgagccgc accgattcct cgtacgtcgg ctgttcgttc
     9121 gatatggtgt ggacggtatc catcatttcg gatcacgcaa acgcaacaac gtgggaagaa
     9181 aaatagatcg ccgttggggc cgttgttatc tatgcattga cgtgctcgag aagccactag
     9241 gcgtatccct cgtacgtcag cccaattagt acgctggtat ctgttgtgct atcccggcgt
     9301 gagcccttat gcaacatttc tacacgcctt tcgcgcccgt cagcggatcg cgcgtccagg
     9361 cgtcagcatt ggcctacgag tacgcccgtt cggctcatcc tacggtcttc acgccgatgt
     9421 ttttctagct ggannnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnncgatctg
     9541 ttggagcaca tccgcagctt gcatccctcg acgcctgttc ttgtgtacag catgcactct
     9601 gaagaaagtt atgccgtgcg gatgatccga agcggggcca gcgggtacct gaacaaatcg
     9661 acgggactcg atgaactcgt ggcggctatg cggtcaatcc tcgcagggca ggaattcatc
     9721 aatccggcgg tggcgcgctg tttgatcgag cgcatgcgca ccaaggattc cggtcaactt
     9781 cacgatgccc tgtccaatcg ggaatttcaa attctcagga tggtcgcgca gggtgaatcg
     9841 ctcaagcaga ttgcactcac actctgtgtc agcgccaata ccgtcagtac ctaccggacc
     9901 cgtattctcc agaagctccg gctgaagacc aacgccgagc tgacgcgtta tgcgctggaa
     9961 catgcgctta tttgacaaga ccgcagagat cccccacagt cacgcaccta gagctcattc
    10021 gtcaaacgag tactcatcgc gccttcgcgt gagaaatttc ccggttcgat acgggtaacg
    10081 ggcgcgtctt gacggcccgg cattcagggc agaaccaggt gaccgtgtgc cctttgggat
    10141 tggtccacca gaacaacacc cgtgacgcac agcgcggaca ttgcgtcgca ggggcagtct
    10201 ccttctcggt cagggccgtt tgaacatgcg actgttccat agatcctccc gctggttctt
    10261 cgtgacatct tcgaacacca ggagcgtgtg acctctgaat tggcaacggt gaaacgtgcg
    10321 gattgcgaac cgtgcttctt ctttcgtcga catggtcacg cgcgcaactc ccagaggcat
    10381 gccgtccgca tcaatgacga tctccgctgc cgtgaccgtg ccacaagacg aaaacaacgc
    10441 gacgatgtcg gcccgcgtga ccgtcgacga caggccgtcg atcaagagac tcaggtcaca
    10501 tggagtatgc aagggacggc tccacccagg tgcattgctg gaactcgctg tggggcgagc
    10561 gtacgcggtc ctggtacaaa tcaccgccag caaactagga atattcctgt aaaggtttcg
    10621 tgacggccag ccgcttacat tttcactagt agcctagtaa ctctcccaga gtattgagga
    10681 tgacgccttc actggggcgt cgttcgaatt caaagagtta gctgtcgaga gctggcagga
    10741 cccgtgtggc ggtattactg gtattcacca gggaattggt gcgagcttgc cgtgatcgga
    10801 aggacgcggc cgtctaagag tagccacgcc catgtcgtac aggaaggaat aacacatgaa
    10861 ctcttgcgaa ggtggagcag gtaaggtgat cgtccttaca taggatgatc gttgccgctg
    10921 gtcagcggca ggatcacatg taccatagtg ccgactccga tttgactggt gacgttcaac
    10981 gtcccattca gcaattgcgc acgctccttg aggctgacga gccccaaccc tcgaggggac
    11041 tgtttcatcg ttttgacgtg gaagccgcgc ccatggtccg tgacgtagag ggacaaggtg
    11101 ttctcgttct tgatgagccg cacctcgacg cgtgatgcct gggcatattt cacgacgttg
    11161 tgcagcattt cttgtaaggt cctgaagagg cacgtcgaaa tgacttcggg cacccgtctc
    11221 gggacatcga tcgcgtgaaa gtctaccggt agctcggtca cttcaatgaa gtccttcagg
    11281 taactgcgca tcgcctcttc aacacccatc gtgtcccaca tggctggatg caagccatag
    11341 gcgatgtgcc gcacggattc cagcgttcgc ttgatctgtt cattcagcat ccgcaccttg
    11401 tgcgtgagcg gctcgtcgca acagcgttca atggaattga cggagaacat catcatggcc
    11461 aactgctgac aacagttgtc gtggagctcc cttgcgatgg cgcgtcgctc ctcgtcctga
    11521 atgttgagca actgcgcatt caggtcttga agtttttgcc ggctggtccg caattcgtct
    11581 tcctgcacct tcagttgctg ctcagcctcc ttgcggcggg tgatgtcgat caccgccagt
    11641 cgcatgatat ctttttgccc ctgcgccggg ctgccttcca acaacacatt catcagggct
    11701 cgtggttggt catcggaggc atcgccgaga tccacttcgc agctcagacg ttttcgttcg
    11761 aaacagactt gtttgcaaaa ttcgatgaac cgccggcgtt gcgcgaccgg catgaacaga
    11821 tggaaccgcc ggccgatcaa gcggttcatc ggctggtgca gcatggctgc tccggcagga
    11881 ttcacgtcgc agatggctcc gcgcggattg agcgaaaaat atccgacagg aatggactca
    11941 tagagctcca catagcggtt gcggctttcc tccaattcta gatgagtttg ccgaagctct
    12001 tcgcattgaa ggcgaagtgc cacatggtgc actcgaagtt catgtaccaa ctgcgcagtc
    12061 tcggttgcgg actgatcaat gggcggtgta tgcgcacttt cgcgcaaata ggcttctgct
    12121 tttctgcgta ggcgttcgat ttgggcccct gatgtcggca tagtgtcctc tttacctgcg
    12181 gaggatgaag tggtcagaat gctggggccg gtcgaaaaaa ttaaacggga ccagcccttt
    12241 gatcgcaaga ggtgacaatg gccgctgcga taccgggaaa gagatccgga taatgaactg
    12301 tgaggtaaaa caccagctgt attctacggg gttcgttcgg gacgtacaat cggagagtca
    12361 ccctcagcat tcaacgggct atacgttggc cactttaatc acgtcgaagc gatcgatcat
    12421 tggattttgc tcttcactgg atcatgcgtc agtgcaatac cgccatgata gtcgatcgga
    12481 atcagtccgt tcaccgcgtc atctccaaca cggcgcaata cgatgccggc aacccttgtt
    12541 ctcgagcgat gggccgcgaa ctggaagatg ggatcagatg tcgtgcctgg tgctgctagg
    12601 ctcctttgga atgcgacgaa acagcatgcg atcctgggac agatcctgat catgacctgt
    12661 ggactcgctg cgcacatgga ggaggccctt atcacgccca acgtcgaaca tgaaccctgt
    12721 tggcagccct ggctctggtt ggcccgcgaa tacggctacc gcgcctgttg gtcatttccg
    12781 gtgcgaacct tcggagggcc gattctgggc acgcttgcgt ggtatttcaa agatcctcgt
    12841 gaaccctcct tgcgtatgat ggagttggca gccacgttga cccatgcggc cgccatcatt
    12901 atttcccgcc accgggaagc ggaggaacga acccgggtgg aggcggccct cagggaatcg
    12961 gatgcgcggt atcgcgcttt cgtcgccgtc acatcggaca tcgtgtacaa gatgagtgcc
    13021 gattggagtg agatgcagag cttggtcggg aaagagttca tcgccagcac cgaacggccg
    13081 cgccgagact ggatggacgc ctatatcccc gatgccgacc gcacggtcgt ctgggaggcc
    13141 atcggcgcgg ccattcactc caaacaggcc tttgaactgg agcaccaggt cattagactc
    13201 gacggcacga tcggctggac ctactcacgg gccgtgcccc tcttcgatca gaagggcgag
    13261 atcgtggagt ggttcggcac agccagcgat attacggagc gcaagcaggc cgaggcccag
    13321 ctcaagaccc gcaatatcga actggagcgg ttcaacaagg tcatggtggg acgggaactc
    13381 cggatgatgg agttgaacca caagagccct gggcggcagg ggttgcagag tgaatcccca
    13441 ctggaccagt tcaccatcga agcgcagagg ccggcggctg aaccagggca gggtgatcca
    13501 ggcggcgaat ctccccgtcg agcgtgaccg gcattctggc agcaaaccta cgtgatctct
    13561 ctgacatgtg gttttccctg aacagccagt cctgattgac caggggcggg ggtgagagac
    13621 catgagaatg acggtcgacc agcatgtggt ggcggcggaa tggcaggcac gcggcttcag
    13681 ttgtgatctt tgggttgatc cgccagggca agtatgggag gattaccgcc acgcgaccga
    13741 tgaggtgatc atgctggtcg cgggccggtt ggaactggag ttcgggggac gctgtctcac
    13801 gcctgttccc ggggaagaaa ttcttattcc tgccggggtg tcccacacgg tgagaaatat
    13861 cggtgggacg actgttcaat ggctctacgg gtacaagcgg gttcatacag gctgatgaac
    13921 tgactcagca gagggagagg agccgatgcc gacaacgacg caatttgtgg tgagtggaca
    13981 gagcaagccc ggtgtgctgg cctcagtggc ggcggtgctg ggagctgccg gggtcaacat
    14041 caaggccttt tccgcgccgg aagtgaccgg gccgggaaag ctgcggttga tcgtggccga
    14101 tgtcgatgcc gcgcgaatcg cgctgagaaa agccaaggtc aaattccgcg aagagacagc
    14161 cctgattttg agcctggaga ataagccggg cgcgttgaaa caagtggccg attcgctcac
    14221 cagagcccgc atcaatgtga agtgcggcta ttgcacgccg tcgcgggaag gcaaacgcgc
    14281 catcgtggtg ctgaccgtgt cgaacaccac caaagccctc ggggtgctgc gcacccattc
    14341 actcgacgaa tt
//
LOCUS       DAOQPD010000097        14336 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_2166_length_14336_cov_22.133254, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000097 DAOQPD010000000
VERSION     DAOQPD010000097.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 14336)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 14336)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14336
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2166_length_14336_cov_22.133254"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1861)
                     /locus_tag="PK063_16565"
     CDS             complement(<1..1861)
                     /locus_tag="PK063_16565"
                     /inference="COORDINATES: protein motif:HMM:NF014763.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cache domain-containing protein"
                     /protein_id="HMZ98716.1"
                     /translation="MRAARRTGGLQRKFFVALLIVGIVPGMAALWATYRSSTASLKEA
                     IGEGFQEIARSTSIRLAGAVDDEIDRAGRLAISVANQHAQAQSKADSNKTEAARVHST
                     HRPVNSPVTAAYLEDWAREARHYLRVTVADHRGLVIASTDRALPPQQADQSWWREAMQ
                     APAGTAYVSNVTIDPAINDATFHVAVPIVEKAGGAVTGAVDLVIRHTLLTQLILPIHI
                     GNTGHAMLLDTQGTPLICPVLPPTAHLIPANLMNRLALDHPLWLVAEDDAHGGRDAIV
                     GASPVRFSHPLTRSSLEGNRWYAFVRQAPEETYAPIYSLLLSVGVIGFGLVIALSMFG
                     FVVGYRIVRPLTALQREAEGLRLTLATTQTDHALPLAATPLPREYRTGDEIEDLATTF
                     SAMRAVLEENLRTIRAQQHELIRQEKLASVGQLLAALAHDLRNPLGVIRSSAQVVLEG
                     PQEEGIRHEMARYIIDEVDKLSQRLNDFLRYARQKPPDLADCAAEGIIGAALKQWEAQ
                     GGHEHIRVEQRFSHDLPMIRIDPEQIKDALVNVLINAREAMTEGGGTLTLTTRSAEGG
                     TVEINVTDTGSGIAPDHLGRIFEPFFTTKTYGTGLGLTNVKRLVEDNGGTLIVT"
     gene            complement(1861..3246)
                     /locus_tag="PK063_16570"
     CDS             complement(1861..3246)
                     /locus_tag="PK063_16570"
                     /inference="COORDINATES: protein motif:HMM:NF012385.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ98717.1"
                     /translation="MHAPTLLIVDDEERMRRLFELVLKAAGYQLLLARSGDEALHMLQ
                     EHDSIDMIITDLQLGTVSGMDVLEAAHKQAPDVPVLIVTGYGTVKSAVEAMQKGAYDY
                     ISKPVDNEELKIVIARALQVRQLARDNRTLRAGLQEQFGFDRIVSVSKEMELVKRLAK
                     EVAQTDATVLITGESGTGKDLLARAIHLASPRAQGPMVALNCAGIPEHLLESELFGYE
                     KGAFTDAKKSKPGRFQMADRGTLFLDEIGELSLTAQAKLLRVLEQHVVEPLGGVRSIP
                     VDLRVIAATNQELPDLIKAGRFRLDLYYRLNVYQLRMPPLRERPGDIEPILTQFLDRA
                     RRERGSRIKGIAQNALALLTQYPWPGNVRELHNVVEWLTITCKQDMIQPEHLPASLTA
                     AAPQSSASPAGAPSLLSLGLSVEEVEKAMLQEALAKSGGNVSEASRLLKITRNTLRYR
                     MAKHNLSQPQG"
     gene            complement(3336..4376)
                     /gene="queG"
                     /locus_tag="PK063_16575"
     CDS             complement(3336..4376)
                     /gene="queG"
                     /locus_tag="PK063_16575"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR00276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HMZ98718.1"
                     /translation="MRETVMPEPLTALITQAARELGFDVVGISRLPPQPAPNHNPSVS
                     PHRLLDRLHEWLQRGFHASMNWMTRDPERRADPALVLPGCRSIISVGMNYYTDHRADE
                     RPGNGRIARYAWGLDYHNIMGDRLTQLSERLATLAPEDRHRAYVDTGPVMEKAWAQQA
                     GLGWIGKHSNLVSPEFGSWLLLGEILTTLELDADEAGTDLCGSCTLCIQACPTGAITE
                     PYVVDAGRCISYLTIELRGSEPTLSEELRRGIGNRIFGCDDCLDICPYNHQAEPTSEP
                     GFQPTPLTTSPSLRSLMDMNEATFAATFKQSPVRRAKHAGLQRNVSWALANEAAPAGN
                     GTPASSSSRDSR"
     gene            complement(4361..4735)
                     /locus_tag="PK063_16580"
     CDS             complement(4361..4735)
                     /locus_tag="PK063_16580"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98719.1"
                     /translation="MSWLVRLISPVLLSVQIALHVMPFDAQAQAPADSAATTEHSCSF
                     GMAKGDPAHQCQVPIPAGCVIATFPGTDKPWTTVSKAGRTFCAFDKKGTDWKNKITGQ
                     CTRCDSSHCTGQFMVRFECAKP"
     gene            5005..5811
                     /locus_tag="PK063_16585"
     CDS             5005..5811
                     /locus_tag="PK063_16585"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ98720.1"
                     /translation="MTGNNPVFKPFSDCTMAQEKILIVDDEVVVAEDIRRQLRSLGYV
                     VVGVVASGSEAVDMAGEHRPDLILMDIKLKGPLDGIDAARMIQARYGTPVIYLTAFSD
                     EDTLKRARYTLPLAYLIKPFVSSDLRAAIELALFRHRVLRIAEQRGRWLDSVLQSMSE
                     AVVTIDAQGKVTLLNQAAEGLTGWSQPDALGKPIQDVMVVVDAERRTPLVNPALSVLQ
                     QIKAGDRGTRPFLLLSRQGVEHVIHESATVIHDEQGGLTGAVLVFRLAIE"
     gene            6087..6680
                     /locus_tag="PK063_16590"
     CDS             6087..6680
                     /locus_tag="PK063_16590"
                     /inference="COORDINATES: protein motif:HMM:NF015331.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SRPBCC family protein"
                     /protein_id="HMZ98721.1"
                     /translation="MVQLMSFLGTLLGCLMAFVLATTPQSWAGEVGSIHLLRPLLVQS
                     EPGGGVKATATLLFPGSPSVLHSILTEYRKWPELFETRMRMAQVEEREGHVLTDVYIS
                     HALLPGEQRLLCESQVLPGGGLVTDLKGGDFKQYHREWRLQAAGEGTQTRAEFELLVE
                     PKTMIPDWLIAVAMERELTVHFRLLRQRALDLVTKGR"
     gene            complement(6664..7842)
                     /gene="thiI"
                     /locus_tag="PK063_16595"
     CDS             complement(6664..7842)
                     /gene="thiI"
                     /locus_tag="PK063_16595"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: protein motif:HMM:TIGR00342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA U4 sulfurtransferase
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HMZ98722.1"
                     /translation="MHCAIIHYHELALKGRNRDFFEQRLVRNIRLALKDLKIRRIESL
                     QGRIRVTIPEDVTPDLVTERLRRICGVSNFLLSESVPLDIREPDLSSIKQVAQRQLGT
                     QTFTSFRVTAKRADKRLPLTSMDVEREVGAYLHEAMGKAVKLKQPDVTLYIELLTKEA
                     HVAARKIEGPGGMPVGTSGKVACLISGGIDSPVAAYRMIKRGCKAVFVHFSGRPLVSR
                     ASEEKVQELVQLLTTYQYHSKLYIVPFGEIQQEIVANAPAAFRVVLYRRIMVQIAQEL
                     ARREGCWALVTGDSLGQVASQTAENLVVVENAAEIPLLRPLIGMDKIEITEQAQQIGS
                     FTTSIEPDQDCCKLFVPLHPSTRTKLEDIVRIERGLEISAFVKRGVEKAELTTFTFPS
                     "
     gene            complement(8146..9072)
                     /gene="trxB"
                     /locus_tag="PK063_16600"
     CDS             complement(8146..9072)
                     /gene="trxB"
                     /locus_tag="PK063_16600"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014450348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HMZ98723.1"
                     /translation="MHHLVIIGSGPAGLTAAIYAARANLSPLLIEGWQSGGQLTTTTE
                     VENYPGFSKGIMGPELMKEMRGQAERFGTEFLTGDVSAIDLSTRPFRLTIDGEQTIGA
                     SALILATGASPIRLGLPNEHRLTGYGVSTCATCDGYFFRGQDLVVVGGGDSAVEEATF
                     LTKFARTVTLVHRRDKLRASKIMQDRAMNNEKISFAWNSIVEDILGKDLVTGVRLKNL
                     VTGHSTDLPCAGVFVAIGHRPNTDLVKGQLEMDEQGYILTSRGTNTSVPGVFAAGDVQ
                     DAKYRQAITAAGSGCMAAIDAERFLESALHSL"
     gene            complement(9182..9802)
                     /gene="coaE"
                     /locus_tag="PK063_16605"
     CDS             complement(9182..9802)
                     /gene="coaE"
                     /locus_tag="PK063_16605"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247713.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HMZ98724.1"
                     /translation="MVSSRPMIFVGLTGGVATGKSTVAKMLERCGALVIDADALAHQV
                     MEPGKPAWRAIVKTFGPAVINPDRTINRPALGTMVFRNRARLRRLEQIIHPRVAREQA
                     RLTRLAVRKDPNAVVIYDVPLLYEAGIDARVDKVIVVTADRETQIARLKKRNGLTRSE
                     ALRRIRNQWPLRKKVAAADFVLDGTTARPRLFTLVKSLYRELARLA"
     gene            9868..10899
                     /locus_tag="PK063_16610"
     CDS             9868..10899
                     /locus_tag="PK063_16610"
                     /inference="COORDINATES: protein motif:HMM:NF019236.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030599 - pectinesterase activity
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pectinesterase family protein"
                     /protein_id="HMZ98725.1"
                     /translation="MKIMNYWILQIAFLCVSVGTVSMVSVKAEEPPAERQPLVVALDG
                     SGQYRSIQEAVDAAKKGDTILIRPGAYPEDVTIHSKENVRLIGAGMDQVTILGRERVG
                     VFHIGKWPYGATNIEISGITVNEHGGHAMGMFNGRGIHFHHARVKGMLFTQQVEDVRI
                     ENCDIGGSETTGVQFANSQAVMRGNFIHDNDHGVSVAGKSTVRLEHNVITRSLFEAVI
                     VNDQAQAVLVGNTFVKNGGGAAFLGTSQNEASGNIVSLNTYGFVVAASSRVLFSYNAM
                     QNSGSNYLRSGTPNQPAPELKPDSDLTVDPRFVDTAQDDFRLRADTSLVKIGTFPYLG
                     ALPPLSASR"
     gene            11056..11241
                     /locus_tag="PK063_16615"
     CDS             11056..11241
                     /locus_tag="PK063_16615"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98726.1"
                     /translation="MASFRFDLEKRSTDGIPNLAEVESGKLLGAILPMSEQAQLQLRD
                     SIEVIDYLMNQETVVWS"
     assembly_gap    11259..11358
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            11423..>12945
                     /locus_tag="PK063_16620"
     CDS             11423..>12945
                     /locus_tag="PK063_16620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosidase"
                     /protein_id="HMZ98727.1"
                     /translation="MSTSTGKKSVPVPPSAEQQRLDDDDLRRKHWKRWGPYLSERAWG
                     TVREDYSPYGTAWEFLPHDHARSKAYRWNEEGLAGISDRHQFICLALALWNGRDPILK
                     ERLFGLTGNEGNHGEDCKEYYFYLDSTPTHSYMKFLYKYPQAAFPYTRLIEENRRRSR
                     TDPEFELLDTGLFDDDRYFDIVVEYAKASPEDLLLRITAINRGPEPSELTVLPTIWFR
                     NTWSWGIDVRRPRMRQGESSPGVSAVEFDHEYYGRRRFLCDGAPDLLFTENETNTRRL
                     YGDSDGARYVKDGINDYIVQGDKNAINPDRIGSKAAAHYVRSAMPGQPVTIRLRFTNG
                     SAEGALDPEAFDAVFAARLKEADEFYAHLAPPDLSADARLVQRQAFAGLLWSKQFYHY
                     EVDRWLKGDPAGPEPPPERLRGRNADWTHLYNADVISMPDKWEYPWYAAWDLAFHCLP
                     IALVDSRFAKDQLVLMLREWYMHPNGQIPAYEWALGDVNPPVHAWAAWRVYKIEKKR"
     assembly_gap    12946..13045
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <13046..13924
                     /locus_tag="PK063_16625"
     CDS             <13046..13924
                     /locus_tag="PK063_16625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosidase"
                     /protein_id="HMZ98728.1"
                     /translation="ASKFFEHFVYICRAMNNIGNAKIELWDREDGFFYDVLHLPDGKT
                     FPMKVRSMVGLIPLFAVETLDSELIDQLPRFKHRMQWFIENRPDFGLHIETQSQDGEV
                     RRFLSLVNRRRLAKVLRYLLDEQEFLSPHGVRALSRYHKDHPYVFSMMGTSHCVEYQP
                     AESSNGLFGGNSNWRGPVWFPVNYLLIESLQKFHYYLGESFRVEYPTGSGQRRNLAEV
                     AAELSRRLTHTFLRGPDGRRPVYGGTAKFQQDPHWRDLLLFYEYFHGDNGAGLGASHQ
                     TGWTGLVAKLIQQSGE"
     gene            13939..>14336
                     /locus_tag="PK063_16630"
     CDS             13939..>14336
                     /locus_tag="PK063_16630"
                     /inference="COORDINATES: protein motif:HMM:NF023855.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen debranching enzyme N-terminal
                     domain-containing protein"
                     /protein_id="HMZ98729.1"
                     /translation="MTIDSRHCQDLDGALNLEWLETNGRGGYASGTVAGANTRRYHAL
                     LLIARHPPVDRVVLVNHVEEFVESGGRTFPLSTNLYHDAVHPEGFQYCEEFSADPWPT
                     WRYAGHGIRLVRELLCPQGRDLVILRWRLL"
BASE COUNT         2743 a         4043 c         4348 g         3002 t
ORIGIN      
        1 tggtcacgat caaggtcccg ccgttgtctt ccacgagccg tttgacgttg gtgaggccga
       61 gtccggtgcc gtaggtcttg gtcgtgaaaa atggttcgaa gattctccca agatgatcgg
      121 gagcgatgcc cgatcctgta tcggtcacgt tgatttccac cgtgcctcct tccgcgctgc
      181 gagtcgtcag ggtcagagtc cctcctccct ccgtcatcgc ttcccgggca ttaatcagca
      241 cattcaccaa cgcatctttg atctgttcag gatcgatgcg aatcatgggc agatcgtgtg
      301 agaaccgctg ttcgacccgg atatgctcat ggccaccttg cgcctcccat tgcttcagcg
      361 cagcgccaat gatcccttcc gcagcacagt cggccaggtc cggcggtttc tgtctggcat
      421 aacgcaaaaa gtcgttcagt cgctgagaca gcttgtcgac ctcgtcgatg atatagcggg
      481 ccatttcatg ccggattcct tcttcctggg gaccctccag cacgacttgc gcggaacttc
      541 gaatcacacc gagaggattg cgtaggtcgt gagccagagc ggcaaggagt tgtccgacgg
      601 aggcgagctt ttcctgccgg atcaattcat gttgttgcgc cctgatagtg cgcagatttt
      661 cttccagcac ggctcgcatc gcgctgaacg tggtggcaag atcttcgatc tcatcgccgg
      721 tgcggtattc tcggggcaag ggcgtagcag cgagggggag agcgtgatca gtctgagtcg
      781 tcgccagcgt gaggcgcagc ccttcggcct cccgctgaag cgccgtgagt ggtcgcacaa
      841 tacggtagcc aaccacaaat ccaaacatgg acaacgcgat caccagcccg aagccgatca
      901 cgcctaccga caggaggagc gaatagatcg gcgcataggt ttcttcggga gcctgccgga
      961 caaaggcata ccatcgattg ccttccaagc tggaccgggt caacggatgg ctgaagcgga
     1021 ccggcgaggc tcccacgatt gcgtcacggc cgccgtgagc atcgtcctcg gccaccaacc
     1081 ataagggatg atccagagcc agccggttca tcaggttcgc gggaatcagg tgggcagtcg
     1141 gcggcagcac cggacagatg agcggtgtcc cttgcgtatc gaggagcatc gcatggcctg
     1201 tattgccgat atggatggga agaatcagct gggtgaggag cgtgtgccga atcacgaggt
     1261 ctacggcacc ggtcaccgcg cctcctgcct tctcgacaat gggaaccgcg acgtggaagg
     1321 tcgcgtcatt gatggcagga tcgatcgtga cgttgctgac ataggccgtc ccggccgggg
     1381 cctgcatggc ctcgcgccac cacgattgat cggcctgctg cggtggcaag gcccgatcgg
     1441 tggaggcgat gacgaggcct cggtgatcgg ccacggtcac gcgcagataa tgccgcgctt
     1501 cgcgtgccca atcttcgagg taggcggcgg tgacggggct gttgacaggc cgatgcgtgg
     1561 aatgaacgcg ggcggcttct gtcttgttgc tgtcggcctt ggattgagcc tgtgcgtgct
     1621 gattcgccac gctgatggcg aggcggccgg cgcgatcgat ttcatcgtcg acggcgccgg
     1681 ccaatcgaat cgaggtcgag cgagcaattt cctggaaccc ttcgccgatc gcctctttga
     1741 ggctggccgt gctggagcgg tacgtggccc acagtgccgc catgccgggc acgatgccga
     1801 cgatcaataa cgcgacaaaa aatttcctct ggagtccgcc ggtccgtcgt gcagcgcgca
     1861 tcacccttga ggctgcgaca ggttatgttt cgccatgcga taccggagcg tgttgcgcgt
     1921 gattttgagc agccggctgg cttcggacac attcccgccg ctcttggcca gcgcctcttg
     1981 cagcatcgcc ttttccacct cttcgactga caaccctaac gacaggagcg aaggagcgcc
     2041 ggccggcgac gcagacgatt ggggtgcggc ggcggtcaag gaggcaggga gatgttcggg
     2101 ctgaatcatg tcctgcttgc aggtgatggt gagccattcc acgacgttgt gcagttcccg
     2161 cacgttgccg ggccaagggt actgggtcag aagcgcgagc gcattctgag caatgccttt
     2221 gatccggctg ccacgctctc gccgggctcg gtcgagaaac tgagtcagga tcggttcaat
     2281 gtcacccggg cgctcgcgca agggcggcat gcgaagttga tagacgttga ggcgataata
     2341 caagtccagg cggaagcggc cggccttgat gagatcgggc aactcctgat tggttgcggc
     2401 aatgactcgc agatcgaccg gaatactccg caccccgccg agcggctcga ctacatgctg
     2461 ctccagcacc cgcagcagtt tggcctgcgc ggtcagactg agttcgccga tttcatccag
     2521 gaacaaggtg ccccggtctg ccatttgaaa gcggcccggt ttggattttt tggcatccgt
     2581 gaaggcgcct ttttcataac cgaataattc ggattcaagc agatgctcgg gaatcccggc
     2641 gcaattcagt gccaccatcg ggccttgggc acgcggactg gccaaatgaa tcgctcgcgc
     2701 gagaagatct ttgcccgtgc cgctctcgcc ggtgatcaac accgtggcat cggtctgggc
     2761 cacctccttg gccagccgtt tcacgagctc catttctttg gagacgctga cgatccggtc
     2821 gaatccgaac tgctcctgca gccctgcgcg taaggtgcga ttgtcccggg caagttgacg
     2881 gacttgcagt gcccgggcga tgacgatttt cagctcctcg ttgtccaccg gcttggagat
     2941 gtaatcgtag gcgccctttt gcatcgcttc gacggccgac ttcaccgtac cgtatccggt
     3001 cacaatcagg accggcacat cgggcgcctg tttatgcgcg gcttccagga cgtccatgcc
     3061 cgagacggtt cccagctgta gatccgtgat gatcatgtcg atcgaatcat gctcctggag
     3121 catgtgaagg gcttcgtcgc cggaacgcgc cagcaggagt tgatagccgg ctgctttgag
     3181 caccagctca aagagccgcc gcatgcgttc ttcatcgtcg acgatcagga gggtgggggc
     3241 gtgcatggtg tcgcaaccgc tgaggtgggt ccccgactcg gcgaggacgt gagtcgtagc
     3301 ctaccactat cggcgaaaga gaaacagagg ggagcttacc gggaatcacg gctcgatgat
     3361 gaggcgggcg tgccatttcc ggctggcgcg gcttcattgg ccagtgccca ggagacgttg
     3421 cgttggagtc cggcatgttt ggcgcgtcga accggactct gtttgaacgt cgccgcgaag
     3481 gttgcctcgt tcatgtccat caagctgcgc aacgacggtg aggtggtgag cggtgtgggc
     3541 tggaagcccg gctcgctggt cggttcggcc tgatgattat acggacagat atcgagacaa
     3601 tcgtcgcagc cgaaaatccg attgccgata ccccgtcgca gctcctcaga aagcgtgggc
     3661 tcgctgcctc gaagttcaat cgtgaggtac gaaatgcatc gcccggcatc cacgacatag
     3721 ggctcggtga tcgcacctgt cggacaggct tggatgcaaa gcgtgcaact gccgcacaaa
     3781 tcggttccgg cctcgtccgc atcgagctcc agggtcgtca gaatttctcc caacaggagc
     3841 catgaaccaa actcagggga gaccaggttg gagtgcttgc cgatccatcc caggccggcc
     3901 tgctgagccc aggctttttc catgaccggc cccgtatcga cgtaggcgcg atggcgatcc
     3961 tcaggtgcca gagtggcgag ccgttcagac agctgcgtta accggtcacc catgatgttg
     4021 tgatagtcca gtccccaggc ataccgggca atccgcccgt tgcccggtcg ttcatcggcc
     4081 cgatgatccg tgtagtaatt cattccgacg gaaataatgg accggcatcc gggcaggacc
     4141 agtgccggat cggcccgtcg ttccgggtcg cgcgtcatcc agttcatgga ggcatggaag
     4201 cctcgctgca gccattcatg taaccggtcg aggaggcggt ggggagaaac gctgggattg
     4261 tggttcggtg ccggctgtgg tggcaaccgg ctgatgccga cgacatcgaa tcccagctcg
     4321 cgcgcggctt gtgtaatcag cgctgtgagt ggctcgggca ttacggtttc gcgcactcga
     4381 aacgcaccat gaattggccg gtgcaatggc tcgaatcgca gcgggtgcat tgaccggtaa
     4441 tcttgttttt ccagtccgtc ccttttttgt cgaaggcgca gaaggtgcga ccggcttttg
     4501 agacggtcgt ccagggtttg tctgtcccgg gaaatgttgc gatgacacag ccggctggaa
     4561 ttggtacttg gcactgatgg gccggatcac ccttggccat gccgaaactg caggagtgtt
     4621 cggtggtggc cgcagagtca gcaggtgctt gtgcctgcgc gtcgaacggc atgacatgaa
     4681 gcgcaatctg cacactgagt aggacagggg aaatcaggcg gacgagccag gacatcgtag
     4741 agcgctccag tgaaaagggc atggtaccac agccttgttt ctgcggcgaa ccctcatctc
     4801 cggcatgccc cgctatttcc ggccctgatc ttccgattct gtccggacat tgttcaaaaa
     4861 ccaccgtcgg tgtagggaga agcaggaacg cgagggcgta acttggtgca agaacaggat
     4921 cgggcaagtg gcatgttagt tgcgagaacc ggtagaccac tagtgcgtgt gcataggtgt
     4981 gcgacgggac cacgagatcc cggcatgacg ggcaacaatc ctgtgttcaa gccgttttct
     5041 gattgcacca tggctcagga aaaaattttg attgtcgatg atgaagtggt ggtggctgag
     5101 gacattcgtc gccagctgcg gtcgctgggg tatgttgtcg tcggggtggt ggcctcagga
     5161 agcgaggccg tggatatggc tggagagcat cggccggacc tgatcctcat ggatatcaag
     5221 ctcaaagggc cgctcgacgg gatcgatgcc gctcgcatga ttcaagcgcg ctacggcacg
     5281 ccggtcatct atctgacggc cttctccgat gaggacacgc tgaagcgtgc acggtataca
     5341 ttgccattgg cgtatctgat caagcctttt gtgagcagtg atctgcgcgc tgcgatcgaa
     5401 ctggcgctct ttcgtcatcg tgtgctgcgt attgccgagc agcgcggccg ctggcttgat
     5461 tcggtgctgc agtcgatgag cgaggcggtc gtgacaatcg atgctcaggg aaaggtgacg
     5521 ttgctcaacc aggcggcgga ggggctgacc ggctggtccc aaccggacgc gctcggaaag
     5581 ccgattcaag atgtcatggt cgtggtggat gcggagcggc gcacaccgct cgtgaatccc
     5641 gccctgtcag tgctgcagca gatcaaggct ggggatcggg gcacgcgccc gttcctgctc
     5701 ctgagtcgtc aaggcgtcga gcacgtgatc cacgagagcg cgaccgtgat ccacgatgaa
     5761 caaggcggcc tgaccggagc tgtgctggta ttccgcctcg ccatcgagta gctattgggg
     5821 accgcggctc gctgccgtca gtcacggatt taccgatcgc agaaatcggt atcggcggtc
     5881 attccgtcat gctctgcact cgcactccag gcagtcaatc agtatactta tcctatgacc
     5941 tcttccacgg tgattggttc atcggcccgt ccgtttcctg gagtacccat gattcctcgt
     6001 gccaccgtcg aacgcgcctc gatccccttc gtaacaccca gcgttctgcg actcgccagg
     6061 cccttcggta gagactgatg cgtgccatgg tacagctcat gtcttttctg ggaacgctgc
     6121 tgggctgctt gatggcattc gtgttggcga ccacccctca atcctgggca ggagaggtcg
     6181 ggtcgatcca tttgcttcgg ccccttctgg tgcagtctga accgggtggc ggggtcaaag
     6241 ccaccgccac gctgctcttc ccgggcagtc cctccgtcct gcattccatt ctcaccgaat
     6301 atcgcaagtg gcccgagcta tttgaaaccc gtatgcgcat ggcacaggtg gaggagcgcg
     6361 aaggccatgt cctgacggac gtctatattt cccatgcgct gctgccaggc gagcagcgat
     6421 tgctctgtga gtcgcaggtg ttacccggcg gcgggttggt gaccgatctc aaaggcggag
     6481 atttcaagca gtaccatcgc gagtggaggc tgcaggcggc aggtgaaggc actcaaacga
     6541 gagcggagtt tgaattgctc gtcgagccca agaccatgat tcccgattgg ttgatcgccg
     6601 ttgccatgga gcgggagctc acggtgcact ttcgtctcct gcggcaacgg gcgctggatc
     6661 tggttacgaa gggaaggtaa aggtcgtcag ttcggccttc tcgacgcctc gcttgacgaa
     6721 cgcgctgatc tccagccctc gttcgatgcg gacgatatcc tccaatttgg ttctggtgct
     6781 tggatggagg gggacgaaca gtttgcagca atcctgatcg ggttcaatgg atgtggtgaa
     6841 gctgccgatc tgttgggcct gttccgtgat ctcgatttta tccatgccga tgagcgggcg
     6901 gagcaaagga atctccgccg cgttttcgac gaccaccaga ttctccgctg tctgcgaagc
     6961 cacctgaccg agactgtctc cggtgaccaa tgcccagcag ccttcccgcc gcgccagctc
     7021 ctgtgcaatc tgcaccatga tccgccggta taacaccaca cgaaacgccg ccggcgcatt
     7081 ggcgacgatc tcctgttgaa tttcgccgaa cgggacgatg tagagcttgg agtgatattg
     7141 gtacgtcgtt aaaagttgga ccagctcctg gactttttcc tccgatgcgc ggctgaccag
     7201 cggccggccg gaaaaatgga cgaagaccgc cttgcacccg cgcttgatca tgcggtaagc
     7261 cgcgaccggg gaatcgatac ctcccgagat caaacaggcg actttgccgc tggtgcctac
     7321 cggcatgccc ccgggacctt cgattttcct cgctgcaaca tgggcttcct tggtgaggag
     7381 ctcgatgtag agggtcacgt ccggctgttt cagcttgacg gctttcccca tggcttcatg
     7441 gagataggcg ccgacttcgc gctccacatc catcgacgtc aacggcaggc gtttatccgc
     7501 gcgtttggcc gttactcgaa acgaggtaaa cgtctgtgtc ccaagttgac gctgcgcaac
     7561 ctgcttgatg ctcgacaggt ccggctccct gatgtctaac ggcacggatt cgctcagcag
     7621 gaagtttgag acgccgcaaa tgcgacggag ccgctccgtc accaggtccg gagtgacgtc
     7681 ctcgggaatc gtcacccgga tgcgtccctg cagcgattcg atccgccgga tcttcaggtc
     7741 tttgagggcc aggcggatgt tgcggacgag ccgctgctcg aagaaatcgc ggttacggcc
     7801 tttgagggcg agttcgtggt agtgaatgat cgcgcaatgc atagtcccgg tcgctgaaaa
     7861 cttcctccgg ccgcgttctc agtcgcttgt ccttcctcac gtacccactc gtacgctcgg
     7921 tcggccaagc tccctgcggc cttgccggag aaatttttga gcgacctcct tttaattaag
     7981 ttcggtattg gtttgtgaag aattgccgat cgtcgactgc tggcaacttc gttctcggct
     8041 cgacgatatc ctcaacgtac cactgcgggt acgcctccgg tatctgtctc gcctgcggcc
     8101 tcgttggaca accattttga gcatcctgcg ggaggtttag agaggttaga gagaatgaag
     8161 cgctgattct agaaaccgtt cggcgtcgat ggcggccatg cagccggagc cggctgccgt
     8221 aatggcctgc cggtatttcg catcctggac atcgcctgcg gcaaacacgc cgggcacact
     8281 ggtgttcgtc ccgcgcgagg tgaggatgta gccctgctcg tccatctcca attgaccctt
     8341 gacgagatca gtgttgggac ggtggccgat ggcaacgaag acgccggcgc aggggaggtc
     8401 tgtggaatgg cccgtcacga ggttcttgag ccggacaccg gtgaccagat ctttcccgag
     8461 aatgtcttcc acgatggagt tccaggcaaa ggagatcttt tcattgttca tggcccggtc
     8521 ttgcatgatc ttggaggcac gcagcttatc gcggcggtgc acaagggtga cggtgcgcgc
     8581 aaacttcgtc aggaaggtcg cttcttccac cgcgctgtcg ccgccgccga ccacgaccaa
     8641 atcctggccg cgaaaaaaat atccgtcgca ggtggcgcag gtcgagacac catacccggt
     8701 cagacggtgt tcgttcggca agccgagtcg aatgggggag gcgccggtcg ccaagatgag
     8761 agcgctcgcc ccgatcgttt gttctccgtc gatggtcagg cgaaacggtc tggtcgacag
     8821 atcgatcgcg gagacgtcgc cggtcaggaa ctctgtcccg aatcgttcgg cctgaccacg
     8881 catctccttc atcaactccg gccccataat ccctttcgaa aacccgggat agttttcgac
     8941 ttccgtcgtg gttgtaagtt gtccgccgga ttgccagcct tcgatgagaa gaggcgacag
     9001 gttggcccgc gcggcgtaga tggccgcggt cagacctgca ggtccggagc cgatgatcac
     9061 gagatgatgc atacgcggat gctaacacac cgatgctgcg agggaaaagc cagaggcacg
     9121 gcatttgggt aacgattcgc acggatcacg gatgaccgaa ggctgctggg tcgcagatcc
     9181 gctaggcgag cctggccaat tcgcgataga gcgatttgac cagcgtaaac aggcgcgggc
     9241 gggcggtggt tccgtcgagg acaaagtcgg cggccgccac ttttttcctc aggggccatt
     9301 gattacggat gcgtcggagg gcttcgctgc gggtcaatcc attgcgtttc ttcaatcggg
     9361 cgatctgggt ttcccgatcg gcggtgacca cgatgacctt gtccacgcgc gcatcaatgc
     9421 cggcttcgta gagaagagga acgtcgtaga tgacgacggc gtttggatcc ttgcggacgg
     9481 ccagcctggt aagtctcgcc tgttctcgcg cgacgcgggg gtggatgatc tgttccaaac
     9541 ggcgcagcct cgcgcggttt cgaaacacca tggttcccag agccgggcga ttgatcgtcc
     9601 gatcgggatt gatgacggcg ggtccgaacg tcttcacgat cgcgcgccag gccggcttac
     9661 ccggctccat cacctgatgt gccagtgcat ccgcgtcgat gacgagagcc ccacatcgtt
     9721 ccaacatctt ggcgaccgtg cttttcccgg tggcgacgcc gcccgtgagg cccacaaaaa
     9781 tcatagggcg cgaagatacc atgggggtcc gatccccgca acgaggctcg gttgacttct
     9841 cgctatggcc agcggtatga ccatcctatg aaaataatga actattggat attgcagatc
     9901 gcatttctct gtgtctcggt cggcacggtg agcatggtct ccgtgaaagc ggaagaacct
     9961 ccagcagaac ggcagccgct agtcgtggcc ttggacggct cgggccagta tcgctccatt
    10021 caggaagccg tggatgccgc gaaaaaaggt gacaccatcc tgattcgccc cggcgcctac
    10081 cccgaagatg tgaccattca cagcaaagaa aatgttcgct tgatcggggc cggcatggat
    10141 caggtgacga tccttggccg tgaacgggtg ggcgtgtttc acatcggcaa atggccctat
    10201 ggcgcgacga atatcgagat ctccggcatc accgtcaatg aacatggcgg gcatgcgatg
    10261 ggcatgttta atggccgtgg catccacttt catcatgcgc gggtgaaagg catgctgttt
    10321 acccagcaag tggaggatgt gcggatcgag aattgcgata tcggcggcag cgaaaccacc
    10381 ggtgttcaat ttgccaactc ccaggccgtc atgcggggga atttcatcca cgacaacgac
    10441 cacggcgtca gtgtcgcggg aaaatccacc gtgcggctgg aacacaacgt cattacacga
    10501 agcctgttcg aggccgtgat cgtcaatgat caggcgcagg ccgtcttggt tgggaacacg
    10561 ttcgtgaaaa acggcggtgg tgcggcattt ttaggcacgt cgcaaaacga agcgtcgggg
    10621 aacatcgtga gcctcaatac ctacggcttc gtcgtcgcgg cctcaagccg tgtcctcttc
    10681 tcctacaatg cgatgcagaa ttcaggttcc aactatctcc ggtccggtac tccgaaccag
    10741 ccggcgcctg aactgaaacc tgattctgat ttgacggtgg acccccgttt cgttgacact
    10801 gcgcaagatg atttcaggct tcgagcggat acgtcgctcg ttaaaatcgg cacctttccc
    10861 tatctcggcg cgctcccgcc cttgagcgca tcgcgctgaa cttcagtcgg aacgcgcaac
    10921 aaattaagag gttacctggc tcgtcttagc gacggaggtc ctgtgctatg cttcatggtg
    10981 agccatggac gtatagggcg cctgtctggc tcaagaattg ctgcactacg accgacaaag
    11041 gattggaggt aagacgtggc cagctttcgc ttcgatctcg aaaaacgcag tacggacggg
    11101 attcccaacc tggcggaggt ggagtccggt aagctcctgg gggccatttt gccgatgtcg
    11161 gagcaggcgc aactccagtt acgggatagc atcgaggtca tcgactatct catgaaccag
    11221 gaaaccgtcg tctggagcta gtgtccctgc ctcctcgcnn nnnnnnnnnn nnnnnnnnnn
    11281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11341 nnnnnnnnnn nnnnnnnnga tgcccggtgc atgctggcgc cgttttgggt caaggacggc
    11401 cagcaagagg agtctgtgtc atatgtcgac atcgaccggg aagaagtctg ttcctgtccc
    11461 gccatcagct gaacagcagc gcctcgatga cgatgacctc cgccggaaac attggaagcg
    11521 gtggggccct tacctcagcg aacgggcctg gggaacggtc cgcgaagact atagtcccta
    11581 tggaacggcc tgggagttcc tgccccatga ccatgcccgc tcgaaggcct atcgatggaa
    11641 cgaagaagga ttggccggca tttctgatcg ccaccaattt atctgtctcg cgctggccct
    11701 ctggaacggg cgcgacccga tcctgaaaga acgcctgttc ggactgacgg ggaatgaagg
    11761 caaccacgga gaagattgca aggagtacta cttctatctc gattccacgc ccacgcattc
    11821 ctacatgaag tttctctaca agtacccgca ggctgccttc ccgtacacgc gactcatcga
    11881 agaaaatcgc cgccgcagcc ggacagaccc ggaattcgag ctgctcgaca ccggtctgtt
    11941 tgatgacgac cggtacttcg atatcgttgt ggagtatgcc aaggcgtcgc cggaggatct
    12001 gttactgcgc atcaccgcca tcaatcgcgg cccggagccc tcggagctga cggtgttacc
    12061 gacgatctgg ttccggaata cctggtcctg gggcattgat gtgcgccgcc cgcgaatgcg
    12121 ccagggcgaa tcgagccccg gggtgagtgc cgtcgaattt gatcacgagt attacgggcg
    12181 gcgtcgattc ctgtgcgacg gagccccgga tttgctgttc acggaaaatg agaccaatac
    12241 acgccgtttg tatggcgatt ccgacggggc gcggtatgtg aaagacggga tcaatgacta
    12301 catcgttcaa ggagacaaga acgccattaa tccggaccgg atcggatcca aggccgccgc
    12361 gcattatgtg cgttcggcaa tgccgggaca gccagtcacg attcgcctgc gctttaccaa
    12421 cgggtctgcg gagggagcgc tcgatcctga ggcattcgac gccgtctttg cagcgcggtt
    12481 gaaagaagcc gacgagtttt acgcacatct ggcgcctccc gatctgtccg ccgatgcgcg
    12541 cctggtgcag cgccaggcct ttgccgggct gctctggagt aaacagtttt atcattatga
    12601 agtcgatcga tggctcaagg gggatccggc cggtccggag cctccgccgg agcggttgcg
    12661 cggccgaaac gccgactgga cccatctcta caacgccgac gtcatctcca tgccggataa
    12721 atgggaatat ccctggtatg ccgcctggga tcttgccttt cactgcctgc cgattgcgtt
    12781 ggtcgattcg cgatttgcca aagaccagct cgtgctgatg cttcgtgaat ggtacatgca
    12841 tccgaacggg cagattcccg cctacgaatg ggccttgggc gatgtgaatc cgcctgtgca
    12901 tgcctgggcg gcctggcgcg tgtacaaaat cgagaaaaaa cgtaannnnn nnnnnnnnnn
    12961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13021 nnnnnnnnnn nnnnnnnnnn nnnnngcgag taagttcttc gagcatttcg tctacatctg
    13081 ccgggcgatg aacaacatcg gcaacgccaa gatcgagctc tgggacaggg aagacgggtt
    13141 tttttacgac gtgctgcatc tcccggacgg caagaccttc cccatgaagg tccggtccat
    13201 ggtgggactc atccctctat ttgccgtgga gacattggat tccgaactca tcgaccagtt
    13261 gccgcgcttc aagcatcgca tgcaatggtt catcgagaac cggcctgatt tcggcttgca
    13321 cattgaaacc caatcgcaag acggcgaagt gcgccgcttt ctctcgctcg tgaatcggcg
    13381 acggttggcc aaggtgctcc ggtatttgct cgacgaacag gaatttttgt cgcctcatgg
    13441 cgtgcgtgcc ctatcccgtt atcacaaaga ccatccgtac gtgttttcga tgatgggcac
    13501 cagccactgc gtcgaatatc aaccggcgga atcctccaac ggcctgttcg gcgggaactc
    13561 gaactggcgc ggtccggtct ggtttcccgt gaattatctg ctgatcgaat cgctgcagaa
    13621 gtttcattat tatctgggcg aatcatttcg cgttgagtac ccgactgggt cggggcagag
    13681 gcgcaatctg gcggaggtgg ctgccgagtt gtcccgccgc ctcacgcata catttttacg
    13741 gggaccggat ggtcggcggc cggtgtatgg cgggacggcg aagtttcagc aggatccgca
    13801 ctggcgggat ctcctgttgt tctatgaata cttccatggc gacaacggcg ccggcctcgg
    13861 cgcgagtcac cagacaggtt ggaccggtct ggtggccaaa ttgattcaac agtcaggcga
    13921 gtaggccgga gatccgtcat gacgatcgat tcgagacatt gccaggacct ggacggggcg
    13981 ttgaatctgg agtggctgga gacgaatggc cgcggaggat atgcgtccgg cacggtcgct
    14041 ggtgccaata cgcggcgcta ccatgccttg ctcttgatcg ccagacatcc gccggtcgat
    14101 cgcgtcgtgc tggtcaatca cgttgaggaa ttcgtcgaaa gcggcgggcg gacattcccg
    14161 ttgtcgacca atctctatca cgacgccgtg catccggagg gcttccagta ttgcgaagag
    14221 ttttccgccg atccctggcc gacgtggcgt tatgccgggc acggtattcg tctggtacgg
    14281 gaactgttgt gtccgcaggg gcgcgatctc gtgatcctgc ggtggcggct gctgga
//
LOCUS       DAOQPD010000098        12872 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_2501_length_12872_cov_25.482874, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000098 DAOQPD010000000
VERSION     DAOQPD010000098.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 12872)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 12872)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12872
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2501_length_12872_cov_25.482874"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..433)
                     /locus_tag="PK063_16635"
     CDS             complement(<1..433)
                     /locus_tag="PK063_16635"
                     /inference="COORDINATES: protein motif:HMM:NF036995.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1016 N-terminal domain-containing protein"
                     /protein_id="HMZ98730.1"
                     /translation="MTTLIPPDYAAWLAELKTTIRTARLKAGLAVNRELVLLYWRIGK
                     EILERQSAQGWGAKVIDQLARDLRAEFSDMRGFSRTNLLYMRAFASAWPEEAIVHQFG
                     GQIPWRHNCVIIDQVKDRPTREGYIRKTIENGWSRSVLELQI"
     gene            1359..1616
                     /locus_tag="PK063_16640"
     CDS             1359..1616
                     /locus_tag="PK063_16640"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98731.1"
                     /translation="MIYACTNDTDLDELIGTQCWEGQRLSFHYGPLVQAMKAGEELVL
                     ENSAALSAFMLAKVRLMLGAMTIEDTSEEIYPHDGFRLTLG"
     gene            complement(2415..3944)
                     /locus_tag="PK063_16645"
     CDS             complement(2415..3944)
                     /locus_tag="PK063_16645"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98732.1"
                     /translation="MNLEQVLEVAAYARPGYSLVSFKESAIPNYLLTTRLLTLEKKSL
                     GPIEEACLGAVSAGLGDPDDLSSFLGLPRVVLNGILAGLNTTECINYSRPTENSDAIV
                     SLTEKGRLTLTTLKEVVPQETVVKFVFDPYLRRIRFVSTASLFKPREVKEQGWYEVPL
                     CGAKRPEVDDVPLADFDKVLQKLPRRDDNTRELLAARRIERREMHFVPCVLLFYRAQS
                     GQEVQVAFYLDDGFSLEHENAFRELGGPELAGANHALTAPEMPVLEDLIEGLNEAQKV
                     SELLSLEQEVSNTMQSEASLDASRIEQIATEGDSERTPSSGVPNAVVARLRAMTQRCI
                     RTHEHPGLLRKALTGSQNRLLIVSPWITHWVIDNMFVMSLEALLRNGVAVTIGYGLAD
                     DEGARGTDKAKQKPAITLQAEKELASIKKRFDNFKLVFLGNTHRKLLVSDDKFAVVTS
                     FNWLSFRGDPGRKARDEFGFLVTEPDDVESIFHDAIELLEKGYDGLAAGRTAEAGKGK
                     R"
     gene            complement(3941..7429)
                     /locus_tag="PK063_16650"
     CDS             complement(3941..7429)
                     /locus_tag="PK063_16650"
                     /inference="COORDINATES: protein motif:HMM:NF024486.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HMZ98733.1"
                     /translation="MNPINGTLTLHGVKKKSDIKKRFLADGRYLISGEGRSGGIASVF
                     RVFDTQEEKHVALKVFRPVNGADPVVEESFRRETLALSDLKHPNIVQILDSGFDEDTN
                     EHFIAMEWIEDVLESFLGRTRLSDWGVFFAKIGRPILEALAFAHSHRTVHRDIKPSNI
                     LLTSEGVPKVCDFGISKIRNFLEPGVTLAHFASFPFAPPEMDDGSYSYSRDVFGFVAL
                     SVAAITNERIVNHNALIAGLEKLKIDEPLKRLLRRSLSLDNPAERQVNAAVLLAEIDR
                     LVPPPPTQKVGRILIGLTNKVKQIIDYDLALKGDPEIQNFVEADLQSAFCIHDPAEPR
                     PGPDGSAPLGRLIRLLGGRYGYVALMAPPAGEKLLLISALEQSASESERNREAASPSR
                     YEFSFGGVLPITSAGNIVKLQDELLQFGADQKADRFQQRQKAIYKTWLDLLSAKTELE
                     RQRKRRCPYRDIEISGSVIRFLVANGADTRTLDGQDIQADSESGETFTGTVISVSDVS
                     VVVQPGERNRVEPSSLHKQGAIVVDTVKADVALDRQKTAVEAVRFGRSINPLLGNYIV
                     DPSSVPVPVTREVSFIQQAMDDDKREAVRTALSEPALMLVKGPPGAGKTTFITEVVLQ
                     TLRSNPNARILLTSQTHVALDNSLERILKESNEEVRAIRIGNESDERITEKAKTLLID
                     RKLPIMRKAALAKGREFVESWAQKSGVDLTSTRMAMALDRHAGLRERLERIQSQIAEF
                     DKTLSRDKNSLEGEVRADMEELQAELVKEQDALTRDLKESLAELRKHETDKETLEHLA
                     DCSAEELRSWADSYVKRSTQVIQLRKMLAVHSEWEVRFGRSPQFKAALVTQAQVVAGT
                     CLGVMGIPGRNEITYDLCIIDEASIATPTEVLVPMARARRTILVGDDRQLSPFQDPEL
                     QTSGILQRFSLTAANQKETLFNHLRDGLPEGLRKVLATQHRMIPAIGNLISACFYGSE
                     LKSADKLPCGLLPRTLQKPVTWFSTSRIDERASKQVGTSQWNGLEVKYISDLIGRIDF
                     ELRHGKAKGTKVSIAVLTGYGEQRARLHQAIQNRRHDWQSFSDIYVNVVDAFQGREAD
                     ILIFSVTRSDVRGLGFLREMERINVALSRGKEYLVIVGDHQFCQEAEGRSNPLKGVID
                     YIRGNPQDCILEEIKP"
     gene            complement(7742..8404)
                     /locus_tag="PK063_16655"
     CDS             complement(7742..8404)
                     /locus_tag="PK063_16655"
                     /inference="COORDINATES: protein motif:HMM:NF024950.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HMZ98734.1"
                     /translation="MGVSVVTGANRGIGLEFAQQLKARGASVVAVCRKGSPELDALGV
                     RVESQINLTERLAWSKIAERLAHDEIDLLIHNAGVLMADSLEEVDPDEVRAQFEVNAV
                     APLFLTRALASRLHPGSKVALITSRMGSMGDNTSGGYYGYRMSKAALNAAGVSLAHDL
                     KPRGVAVVILHPGFVRTAMTRGHGQIDPDESVRGLLQRIDELKIETTGRFLHQNGDIL
                     PW"
     gene            complement(8462..8983)
                     /locus_tag="PK063_16660"
     CDS             complement(8462..8983)
                     /locus_tag="PK063_16660"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF012792.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HMZ98735.1"
                     /translation="MSAPATPHRIEPLGKGHDRDSFSCGSAPLDRYLRQQARQDADKR
                     VAAPFVLIEPPAAQVLGYYTLSASTVDASELPDALTKKLPRYPQLPVTLLGRLAVDQS
                     MKGMGMGEFLLMDALRRSVEAAANIAAMAVLVDAKDEAAEAFYRHFSFLPLQQRPARL
                     YLSMKTIIALFGD"
     gene            complement(8984..9283)
                     /locus_tag="PK063_16665"
     CDS             complement(8984..9283)
                     /locus_tag="PK063_16665"
                     /inference="COORDINATES: protein motif:HMM:NF020265.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HMZ98736.1"
                     /translation="MQTSDPVTDDKTRAARLEARLSVEQKAVLQQAATLSGRTLSEFV
                     VASAQEAAARILREHETIRLSRAEQIAFVTALLDPPAPNERLRQAAAAYRQQMGR"
     gene            complement(9695..10057)
                     /locus_tag="PK063_16670"
     CDS             complement(9695..10057)
                     /locus_tag="PK063_16670"
                     /inference="COORDINATES: protein motif:HMM:NF036995.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1016 N-terminal domain-containing protein"
                     /protein_id="HMZ98737.1"
                     /translation="MTTLIPPDYAAWLAELKTTIRTARLKVGLAVNRELVLLYWRIGK
                     EILERQSAQGWGAKVIDQLARDLRAEFPDMRGLSPRNMKYMRAFAEAWPEEGFVQQAA
                     AQITWFHNCILLDQVKDG"
     gene            complement(10290..10571)
                     /locus_tag="PK063_16675"
     CDS             complement(10290..10571)
                     /locus_tag="PK063_16675"
                     /inference="COORDINATES: protein motif:HMM:NF025120.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HMZ98738.1"
                     /translation="MSNQRFASVWDAIEDTPEEAENMKLRSVLMTALKNHLTRTEMSQ
                     AQAAKLLGVTQPRVSGLMRGKINLFGLDALVNMATAAGLHIEMRVLEAA"
     gene            complement(10571..10912)
                     /locus_tag="PK063_16680"
     CDS             complement(10571..10912)
                     /locus_tag="PK063_16680"
                     /inference="COORDINATES: protein motif:HMM:NF017757.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HMZ98739.1"
                     /translation="MSTTDPRPVEFRGSSLDELRAFPLPARREAGHQLDQVQNGQEPD
                     DWKPMNTVGQGAKEIRIRDAAGTFRVIYVAKFADAVYVLHCFQKKTEKTSKADLDLAS
                     KRYRDLLKELG"
     gene            complement(11236..11661)
                     /locus_tag="PK063_16685"
     CDS             complement(11236..11661)
                     /locus_tag="PK063_16685"
                     /inference="COORDINATES: protein motif:HMM:NF018009.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDDEXK nuclease domain-containing protein"
                     /protein_id="HMZ98740.1"
                     /translation="MGAAQTNFDRALPSPQSDLARDILKDPYTFDFLGITDASNERTI
                     EKALVLRLRDFLIELGVGSAFVGSQNRLEVDGRNGCARLVVLPYSISHGSPISILGSS
                     LCAMYGEAVLRASCHAGWPTLGGVPGRFLGYGKFPRALP"
     gene            12165..12431
                     /locus_tag="PK063_16690"
     CDS             12165..12431
                     /locus_tag="PK063_16690"
                     /inference="COORDINATES: protein motif:HMM:NF013561.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="HMZ98741.1"
                     /translation="MRTTKTLSITLPPEMLARAAEIARREHRTMSELVREALRDYERK
                     NWWSEMNAFGQAKAAELGLTEADVEQAVHDVRRERAGRGPETKA"
     gene            12428..12856
                     /locus_tag="PK063_16695"
     CDS             12428..12856
                     /locus_tag="PK063_16695"
                     /inference="COORDINATES: protein motif:HMM:TIGR00305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004521 - endoribonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative toxin-antitoxin system toxin component,
                     PIN family"
                     /protein_id="HMZ98742.1"
                     /translation="MTVVVADTSVYVSALVFGGVPQAALIKALTVPFRVAVSHALRAE
                     LVETLERKFGWPSSRVAHACAHLWGGAIWCEPVAVQASRDPDDDHVLGCAIAALANVL
                     VTGDKDLLSLHPFKGITIVTPATFLAMPWTVHGDDRAPFV"
BASE COUNT         2570 a         3824 c         3700 g         2778 t
ORIGIN      
        1 cgatctggag ttcgagaacc gaccggctcc agccgttttc gatggtcttg cggatatacc
       61 cctcgcgggt cggccggtcc ttgacctggt cgatgatgac gcagttgtgc cgccatggga
      121 tttgtccacc aaactggtgg acaattgctt cctccggcca cgctgaggca aatgcccgca
      181 tgtagagcag attggtgcgg gaaaaacctc tcatgtcgga gaactcggca cggaggtcgc
      241 gggccagttg gtcgatgacc ttcgcccccc agccctgggc ggattgccgt tcgagaatct
      301 ccttgccgat gcgccaatag agcaggacca gttcccggtt aacggcgagg ccggccttga
      361 gtctcgccgt gcggatggtg gtcttcaact ccgcaagcca tgcggcgtag tcgggaggga
      421 taagggttgt cacgcttggg gtgtcatggt ttgcggcgag tcacttgatc tggaattgtc
      481 caccaggctg ctgcactgtt gcgcgacggt agctcgttgg gcggtacgct cagcctttcg
      541 gtgactcatg cggaaatccc tacaccccca aaagtctgat gctgacgacg atcggatatg
      601 tattcggaat tgtacagcgg gaagattctc tgcagacgat ttgtggctcg ccagatcaag
      661 cgcgtttgcg gagtcaagcg tcaatcgacc cggcacgcct cccagggtcg gcccgccggc
      721 atggaacgaa gcgcgaagaa cggcttcgcc atacatcgcg ccgaacccac cgctagggaa
      781 tagatgggcc atcctggcca gatcggaggc cgtgtctacc agaccagaga ggattcggca
      841 ccggcaacgc cagtgctgcg cactcttgtc caacctgcgc aaatctgcaa tcgaccatgg
      901 agcaagaaag ggcagtaacg tgagcaggtt tcacgcgatc atcctcaggt cagcgatggc
      961 acgttgcagg cctcgaacca cgtcaaccca cgccttgtcg tggctactcc aagtgtttca
     1021 agaaaatgta tctgatgaca ttcccacctg acgggttcgc ccaaaccacc aaagactccc
     1081 tcaactcgca cgatgcgcaa tcgcttcaag aattcttaaa gcagtctgac gccagcccgg
     1141 tgtcgcgggt accaccgtct ccgccagcct gatcgcttcc agatcgtcag gcacgttcca
     1201 ttctcggttg tccattcgca gaaggatgct ccgggcgagg cagtccacca gagagtcttg
     1261 attcggtcaa ttggacctca atttcagatt ccgactcaat ttcttcctgc gatcgtccgt
     1321 taatcaatgc aagaccttct gctctctgga ggaataacgt gatctacgcg tgcaccaacg
     1381 atactgatct cgatgaactc atcgggactc aatgctggga aggccagcgg ctgtcgttcc
     1441 attacggccc gctcgttcag gccatgaaag cgggcgaaga gttggtcctg gagaacagtg
     1501 ccgcgttgtc ggctttcatg ctcgcgaagg ttcgcctgat gctcggcgcc atgactattg
     1561 aggacacctc agaagagatc tacccgcacg atggttttcg gctgacgctc gggtaaggtc
     1621 ggctggatct gctgttcgag caagccaccg gtctcgagaa gcgctacttg caggcgctgg
     1681 atgcccgcga ggatccagac gccgaaagaa gccgggagcc tgctctccgg ttacgggttt
     1741 gccggtgcgg cgatgcaatt gtccgcgatt ggtatggtat cgacggcacc ggcaacgggt
     1801 taaacagcga ggagtcgccc ccacggcaag gatccagcgg tcgtgccgac gccgacgagc
     1861 ttgaattgtc atgctccgtg gaagacttgc tccaacacgc atcgggacgg gacgacgcac
     1921 tggcaaccga ggttgagagc gagatcaacc agtatcgtca ccaggcgcac tgcatcgcgg
     1981 agatgctggc gacgctgggg cgtctgcaac gccttgtaca ctccccgcgc cggacaagcg
     2041 gtggagagca gcgtgcttcc cgtctcaccg cttgcgaggc catcggcgtc gcacccgctg
     2101 ccgcgatcgc ttcactggaa gcagcaggag caaggtcttg acgtttaggt ccgcttccga
     2161 ccctcagcgg tcctacgcgg tatcccgact tctacggctg gtgacagagc agaccggccg
     2221 ttcatggcga ctgctcaccg ggaattcgtc ggccaaagcc gacgtacagc acacgccaga
     2281 tgagaggctg gtcttccgag gtcaacgggc cttcagatca acgagatcgc gaacgtctgc
     2341 tcttctgacg gccgaacgcg aagtctcgac cccttgccac tggtactcct aattcttaat
     2401 cacagtgcca aacgtcaccg tttgcccttt cctgcttctg ctgttcttcc tgcagccaag
     2461 ccgtcgtagc ctttttccag cagttctatc gcgtcatgga aaatgctttc cacgtcatcc
     2521 ggctctgtca ccagaaatcc gaactcgtcc cgcgcctttc tccctgggtc gccacgaaac
     2581 gacagccagt tgaagctggt cacgaccgca aacttatcat ctgaaaccag aagttttcgg
     2641 tgcgtattcc caagaaacac cagtttgaaa ttgtcgaatc gctttttaat gctcgcaagt
     2701 tccttttctg cctgtaaggt gattgcgggc ttctgcttgg ctttgtccgt gccccgcgca
     2761 ccttcgtcgt cggccagacc ataccctata gttaccgcca cgccattcct taacagggct
     2821 tcaagtgaca tcacaaacat gttgtcgatg acccagtgag ttatccatgg agaaacgata
     2881 agaaggcggt tctgcgaacc cgtcagggcc tttcgcaaca gccccggatg ctcgtgcgta
     2941 cgaatgcatc gctgagtcat cgctctcagg cgggcgacaa ctgcgttggg cacgccactg
     3001 gaaggcgtcc tctcactgtc gccctcggtt gcaatctgtt ctatacgcga ggcgtcaagt
     3061 gaagcctcag actgcatcgt gttcgatacc tcttgctcaa gcgagagcag ttcgctgacc
     3121 ttctgtgcct cattcaatcc ttcaatcaaa tcctccagta ctggcatttc cggcgccgtc
     3181 agcgcatgat ttgcgcccgc cagttcggga ccaccaagtt cccggaacgc gttctcatgc
     3241 tccagggaga acccgtcgtc caaatagaag gctacctgaa cctcctgacc cgactgagcc
     3301 cggtagaaca gcagaacgca tggaacgaag tgcatctccc tgcgctcgat cctcctcgcg
     3361 gccagcagct ccctcgtgtt gtcgtctcgg cgcggcagct tctgcaagac cttgtcaaaa
     3421 tcggcaagtg gcacgtcatc aacttcaggg cgcttcgcac cacacagagg cacctcgtac
     3481 catccctgct ccttgacctc tctcggcttg aacagggacg ccgtcgaaac aaaacggatt
     3541 cttcgaagat agggatcgaa tacaaacttg acgacggttt cctgcgggac aacctccttc
     3601 agggtcgtca gcgtaagccg tcccttttcg gtcagcgaga caattgcatc cgagttttcc
     3661 gtcggacgcg aatagttgat gcactccgtg gtgttgagcc cagcgagtat cccgttcagt
     3721 accacccgag gaaggccaag gaacgacgaa aggtcgtccg ggtcgccaag gccggcgctt
     3781 actgccccca gacaggcttc ttcaattgga ccgaggcttt tcttttcaag cgtaagtagc
     3841 cgcgtggtca gcaggtagtt cggaatcgcg gattccttga acgacaccag cgagtagccg
     3901 gggcgggcgt acgcggcaac ctcaaggacc tgttcgagat tcatggcttg atctcctcaa
     3961 gaatgcaatc ctgagggttg ccccggatgt agtcgattac ccccttcagc ggattggacc
     4021 ggccctccgc ttcctgacag aactgatggt caccgacgat gaccaggtat tccttgccac
     4081 gcgataacgc aacgttgatt cgctccatct cgcgcaagaa tccaaggccg cgaacgtcag
     4141 atcgggtgac ggaaaagatc aggatatcgg cttcccttcc ctgaaatgca tcgaccacat
     4201 tcacgtagat gtcagaaaag gactgccagt catgccttct gttttgtatc gcctggtgca
     4261 atcgggcgcg ttgctcaccg tagcctgtca atacggcaat cgataccttt gtacctttgg
     4321 cttttccatg gcgaagctca aagtcgatcc tgccgataag gtcggaaatg tatttgactt
     4381 ccaacccgtt ccattgcgac gtaccgacct gtttcgatgc cctttcgtca attctgctcg
     4441 ttgaaaacca ggtcaccggt ttctgcaagg ttctcggcaa aagcccgcaa ggaagcttgt
     4501 ctgcgctttt cagctccgaa ccatagaaac aggctgatat caggtttcct atcgcaggaa
     4561 tcattcgatg ctgggtggcg agtaccttac ggagcccttc cggaagtcca tctcgaagat
     4621 ggttgaacag cgtttccttc tgattagctg cggtcaggga aaaacgctgc aatattcctg
     4681 aggtctgaag ttccggatcc tgaaatggcg acagctgcct gtcgtcgccg accaatatcg
     4741 ttcgccttgc cctcgccatc gggacaagaa cctcagtggg ggtagcaata gaggcttcgt
     4801 cgatgataca aaggtcatag gtgatctcgt ttcttcccgg tatccccatg actccaaggc
     4861 atgtcccagc caccacctgc gcctgggtca cgagcgctgc cttgaactgg gggctgcgac
     4921 caaaccttac ttcccactcc gagtgaaccg ccaacatctt gcgtagctgg attacttgtg
     4981 tggatctctt tacgtagctg tccgcccaag acctcaattc ttcagcactg cagtcggcaa
     5041 gatgttccag tgtctccttg tcagtctcat gcttcctcag ttctgccagc gattccttga
     5101 gatctcttgt cagggcatcc tgttccttga ccagttccgc ctgcaattct tccatgtcgg
     5161 cgcgaacttc accttcgagg gaatttttgt cgcgggaaag tgtcttgtca aattcggcga
     5221 tctgcgattg gatccgttcc aggcgctcgc gaaggccggc atgtcgatcc agtgccatgg
     5281 ccattcgagt gctcgtgaga tcaacaccac tcttctgagc ccaggactcg acgaattcgc
     5341 ggcccttcgc aagagccgct tttcgcatga tcggaagctt ccgatcgatc aacagagtct
     5401 ttgccttttc agtgatgcgc tcgtcactct cattgccaat ccgaatcgcc cggacctcct
     5461 cattgctctc cttgagtatc cgctccagag aattatccaa tgccacatgc gtctgagagg
     5521 tcagcaagat ccgggcgttc gggttgcttc gcaatgtttg gagcacaacc tcggtaatga
     5581 aggtggtttt gccggcaccg ggagggcctt tgactagcat cagggctggc tccgacagcg
     5641 ctgttcgaac cgcctctcgc ttgtcgtcat ccatcgcctg ctgtatgaaa ctgacctccc
     5701 gggttaccgg taccgggacc gaggatggat cgacgatgta gttccccagt agcggattga
     5761 tcgaacgacc aaatctgacg gcttcgacag ccgtcttctg gcggtcaagg gctacgtcgg
     5821 ctttcacggt atcgactacg atggcccctt gcttatgcaa actcgatggc tccacacggt
     5881 tacgttcacc cggctgcact acgaccgaca cgtcgctcac ggaaataacc gtaccggtaa
     5941 aggtttcgcc cgattcgctg tcggcctgta tgtcctgccc atcaagcgtt cgcgtgtctg
     6001 caccgttcgc caccaggaag cgaatcacgc ttccggaaat ctcaatatcc cgataagggc
     6061 aacggcgttt ccgctgccgc tcaagttccg tctttgcact caacaagtcg agccaggtct
     6121 tgtagatcgc cttttgccgc tgctgaaacc tgtcagcctt ctgatcggca ccgaactgaa
     6181 gtaactcatc ttggagcttg acgatgtttc ctgccgacgt aatgggaaga acaccgccaa
     6241 aactgaattc atacctggac ggcgaggcag cctcgcgatt ccgctccgat tccgaggccg
     6301 actgctcaag tgccgagatg agcagcagct tctcacctgc cggaggtgcc ataagcgcaa
     6361 catagccata gcgaccgcca agcaagcgaa tcaaccgtcc cagaggagcg ctgccgtcgg
     6421 gccctggccg gggttcagcc ggatcatgaa tacagaaagc tgactggagg tcggcctcga
     6481 cgaaattctg aatttcggga tcgcccttca aggcaaggtc atagtcaatg atctgcttaa
     6541 ccttgttggt caggccgatc agaattctcc caaccttctg cgtgggtgga ggaggtacca
     6601 atctgtcgat ttcagccaac aggaccgctg cattgacttg gcgttccgca ggattgtcga
     6661 gcgacagcga tcgacgcaga agacgcttca ggggttcgtc gatcttgagc ttttcaaggc
     6721 ccgcgatcag ggcattgtga ttgacgattc tttcgttggt tatcgcagca acggacagtg
     6781 caacaaagcc aaaaacatcg cggctatagc tatagcttcc gtcgtccatt tccggtgggg
     6841 caaacggaaa tgacgcgaaa tgggccaacg ttacgccggg ctccaggaag ttgcggattt
     6901 ttgaaatccc gaaatcgcat accttcggaa caccttccga ggtaaggaga atgttggatg
     6961 gcttgatgtc ccgatgcacc gttctgtgcg agtgggcgaa agcgagcgct tcaagtatcg
     7021 ggcgtccgat tttggcaaag aacacccccc aatcactcag acgagtgcga cctaggaaac
     7081 tttccagaac atcttcgatc cactccatcg cgatgaagtg ctcgttcgta tcttcatcga
     7141 aacctgaatc gaggatctgg acgatgttcg gatgtttcaa gtccgatagc gccagcgttt
     7201 cgcgacgaaa cgattcctca accacggggt cggcgccatt tacagggcgg aacaccttga
     7261 gggcaacgtg cttctcctcc tgggtatcga aaaccctgaa gactgaagct atgccaccgg
     7321 aacgcccttc gcccgaaatt aaatagcgcc catcggcaag aaatctcttc ttgatgtcgg
     7381 atttcttttt gacgccgtgc aatgtcaaag ttccgttgat tgggttcaat caggatctcc
     7441 ctagatttgc tatttgaatg ttctctgcat gccaaagata ttctcacagg tttcatcttg
     7501 gtcggaaagc gccttgaagg ccgactgtat gtcaactttc cggtgcattg cagcctacaa
     7561 cgcttgcgaa actggggtca gcactggccg aagtgccgaa gtagttcgtc cggcaggttt
     7621 cggagtggaa ctgacgcccg aatgaccaag gttgctagcg actgaccggc cgcttctggc
     7681 cgtgagcgga ccagagattt ccacttggca tccaataccg ccgcggggct ggggcacggt
     7741 cttaccacgg caggatgtcg ccattctggt ggaggaatcg tccggtggtc tcgatcttga
     7801 gttcgtcgat gcgctgcaag agcccgcgaa cagactcgtc cggatcgatc tggccgtggc
     7861 cgcgggtcat cgcggtgcgc acaaaccctg gatgcaagat gaccacagcg acccctcgcg
     7921 gcttgaggtc gtgggcgagg gagacaccgg ccgcattgag cgcggccttg ctcattcggt
     7981 agccgtagta gcccccggag gtattgtcgc ccatggagcc catgcgactg gtgatgagcg
     8041 cgaccttcga gcccggatgc aggcgcgagg cgagggccct cgtgagaaaa agtggcgcta
     8101 cggcgttcac ttcgaactgc gcgcgcacct cgtcaggatc gacctcttcg agagagtcgg
     8161 ccatgagcac gccggcgttg tggatcagga ggtcaatctc gtcgtgcgcg agccgttcgg
     8221 cgatcttgga ccatgccaga cgctctgtca ggttgatctg gctttcgaca cgcaccccga
     8281 gcgcgtcaag ctccggcgaa cccttgcgac ataccgcaac cacgctcgct ccacgtgcct
     8341 tgagctgttg cgcgaactca aggccgattc cacgattggc acctgtgacg actgaaacac
     8401 ccataccgtc cctcctcttc gatccggctt ggataggcgt aaggattcct tcgtaagcct
     8461 gtcagtcgcc gaacagcgcg atgatggttt tcatcgacag gtacaggcgc gcgggccgct
     8521 gttgcagcgg caggaagctg aaatggcggt agaaggcttc ggctgcttcg tccttggcat
     8581 ccaccaggac agccatggcc gcgatgttcg cggcggcttc cacgctgcgg cgcaaggcgt
     8641 ccatgagcag gaattccccc atgcccatgc ccttcatgct ttgatcgacg gccagccgac
     8701 caagcagcgt caccgggagt tgcgggtaac gcggcagctt tttggtcaag gcatcgggca
     8761 attcgctggc gtccaccgtc gaggcggaca gcgtgtaata cccgagcacc tgcgcggcgg
     8821 gcggctcaat cagaacgaag ggcgcggcga cgcgcttgtc ggcgtcctgg cgggcttgct
     8881 ggcgcaggta gcgatccagc ggcgcactgc cgcaggaaaa gctgtcgcgg tcatggccct
     8941 taccgagggg ctcgatgcga tgcggggtcg ccggggccga caatcaccgc cccatttgct
     9001 ggcggtaggc cgctgcggcc tggcgcagac gctcattcgg cgcgggcggg tcgagcaaag
     9061 cggtcacgaa cgcgatctgc tcggcccggc tcagacggat cgtttcgtgt tcccgaagga
     9121 tgcgcgcggc agcctcctgg gcgctggcga cgacgaattc gctcagggtg cgcccggata
     9181 gcgtggcagc ctgttgtagc accgcttttt gttcgaccga caggcgggct tccaggcgcg
     9241 ccgcgcgcgt cttgtcgtcg gtgactggat cgctggtctg catggccttt ctcccgtgtt
     9301 tttgcttgcc gtcgcccgtg caagcgaaag ctctcctaat gtacggcaaa cgtacggaac
     9361 aaacaaggcc tttcttgggc gttcccgctc gcgctacgcg ccagcgggcc gggcctgaag
     9421 tcccggccat ccggtaacga tccctgacgc aaaagccagt gagcggcgtc agcttcgctc
     9481 acgccgggtg acggggcacg gctgcgccct gccccgcatc gacgaccgcc cagcttaatg
     9541 gctgcgccat caagcgtggc ccttcttttg gacgctgctc caggcgcggc gcaagagtaa
     9601 agctccgccg gccggcgagg tatccccgag cttccgcccc ccgcgggggt tgtgcaggcc
     9661 ggttgattcc cctccccacc ggtcgccctt acgcctaccc gtccttgacc tggtcgagaa
     9721 gaatgcagtt gtggaaccaa gttatttgtg cagcagcttg ctgcacaaat ccttcttcag
     9781 gccaggcctc ggcgaacgcc cgcatgtact tcatgttgcg aggggaaagc ccgcgcatgt
     9841 cggggaactc ggcacggagg tcacgggcca gttggtcgat gaccttcgcc ccccagccct
     9901 gggcggattg ccgttcgaga atctccttgc cgatgcgcca atagagcagg accagttccc
     9961 ggttaacggc gagcccgacc ttcagcctcg ccgtgcggat ggtggtcttc aactccgcca
    10021 gccatgcggc gtagtcggga gggatgaggg ttgtcatgct tcggcggtta cggttttcgg
    10081 cgagtcactt gatctggaat tgtccaccgg gctgctgcac tgttgggcgg cggtagcgcc
    10141 gtcgggcggc gtattcctgg tttccggcag agccatggaa aattcacacg ccccaaaaag
    10201 tctggcggtg aagccggttg agtgtggtgg gggagttctc gaaaaccgtt ctccctcgag
    10261 gcggtgcaga acggcgagtt tcgagaaggt caggcggctt cgagtacccg catctcgatg
    10321 tgaagtccgg cagccgtcgc catattcacc agtgcatcaa ggccgaacag gttgatcttg
    10381 ccgcgcatca ggccagaaac acgcggttga gtcacgccca agagcttggc ggcttgcgcc
    10441 tggctcattt cggtgcgggt aaggtggttc ttcagcgccg tcatcagaac ggaacgtagc
    10501 ttcatgtttt ccgcttcttc cggggtgtcc tcgatggcat cccagacgct agcaaatcgt
    10561 tggttgctca ttagcctagc tccttcaaca agtcgcggta acgtttcgag gccaaatcca
    10621 aatcggcttt gctggtcttc tctgtcttct tctggaagca gtgaagcaca tagacggcat
    10681 cagcgaactt ggcaacgtag atgacccgga acgtcccggc tgcgtcacga atccgaattt
    10741 ccttcgcacc ttggccgacg gtgttcatgg gcttccagtc gtcaggctcc tggccgttct
    10801 gaacctgatc gagctgatga ccagcctcgc gcctggccgg aagcggaaaa gcgcgaagct
    10861 catcaaggga actgccccgg aactcgacag gtctgggatc ggtcgtgctc atactataca
    10921 aagttttgta taccgcggca agcgggtatc aggtccaatg gagcaggcaa ccggcttatc
    10981 gtgctttact ttccgttttc tgaagcgacc cccaataggg caggaccagt tccaggttaa
    11041 cggcgagacc ggccttgagc ctctccgtgc ggatggtggc cttcaactcc gcaaaccatg
    11101 cgacgtagtc ggtagggatg aggtttgtct tgctttgggg gtcatggttt gcggcgagtc
    11161 acttgatctg gaattgtcca ccaggcggcc gctcggttga gcgacggtag cgccgtcggg
    11221 ctgcgcattc cgggtttacg gcagcgcccg ggggaatttt ccatacccca aaaatcgacc
    11281 cggcacgcct cccaaggtcg gccagccggc atggcacgaa gcgcgaagaa cggcttcgcc
    11341 atacatcgcg cagaggctgc tgccgaggat ggagatcggc gatccgtgcg aaatagagta
    11401 aggcagaaca acaaggcgcg cgcatccgtt acgaccgtcc acctcaagac ggttctgact
    11461 tcccacaaac gcagaaccga cgccgagctc gatcaggaag tctcgcaggc gcagcacgag
    11521 tgccttttcg atggtgcgct cgtttgacgc gtccgtgatc ccgaggaagt cgaaggtgta
    11581 ggggtccttg aggatgtcgc gtgccaagtc ggactgtggc gacggcagcg cacgatcgaa
    11641 gttggtttgc gcggcaccca cgcgccggtg cgctgcagtc tcgatctgga gttcgagaac
    11701 cgaccggctc tgtcaccgtt ttcgatggtc ttgcggatgt accactcgcg ggtcggccgg
    11761 tctttgactt ggtcgagacg gatgcagttg tgaaaccaca gcatttgtgc agcagcttgc
    11821 tgcacaaatc cttcttcagg ccaggcctcg gcgaacgccg gcatgtactt catgttgcga
    11881 ggggaaagcc cgcgcatatc gagatcgacc cggcacgcct cctcaaggtc ggccagccgg
    11941 catgatacga cgcgcgaaga acgactgcgc cgtacatcgc gccagtctgc cgatggagac
    12001 ggagatcggc tgtccgggcg aactatagat gcttggcccc tggcatcagc gacccgccac
    12061 accgatcacc gggctttcgc gtgcggctcg ctcccaacca caggaacctt ggatattgtc
    12121 caatcgtgct tgacacgact aagcaagatc gatagtttag ggccatgcga acgaccaaaa
    12181 ctctctcgat cactctgccg ccggaaatgc tcgcccgagc cgcggagatc gctcggcgcg
    12241 aacaccgcac gatgagcgag ctggtgcgcg aagccctgcg tgactatgag cgcaagaatt
    12301 ggtggtctga aatgaatgcc ttcggccaag cgaaagctgc cgaacttggt ctgaccgagg
    12361 ccgatgttga acaggctgtg cacgatgtgc gtcgcgagcg cgctggccgc ggtcccgaga
    12421 ccaaggcgtg acggtcgtcg ttgccgatac gagcgtctat gtttcggcgc tcgtgttcgg
    12481 tggtgtgccg caggccgccc tcattaaggc gcttacggtt cccttccgcg ttgcggtctc
    12541 ccacgcgctg agggcagaac ttgtcgaaac gcttgagcgc aaatttggct ggccttcttc
    12601 tcgggtggca catgcctgcg cacacttgtg gggaggggct atctggtgcg agccggttgc
    12661 cgttcaagcc tcgcgcgacc ccgatgacga tcacgtgctt ggctgtgcaa tcgctgcatt
    12721 agccaacgtg ctggttacgg gcgacaaaga cttgttgtcg ttgcatccgt tcaaaggcat
    12781 taccatcgtg acgccggcga catttctggc gatgccgtgg acggtccacg gtgacgaccg
    12841 agcaccattc gtttgagctt ggccaaggcg gc
//
LOCUS       DAOQPD010000099        12230 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_2654_length_12230_cov_21.112279, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000099 DAOQPD010000000
VERSION     DAOQPD010000099.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 12230)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 12230)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12230
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2654_length_12230_cov_21.112279"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(1..950)
                     /gene="prfB"
                     /locus_tag="PK063_16700"
                     /pseudo
     CDS             complement(1..950)
                     /gene="prfB"
                     /locus_tag="PK063_16700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_155970262.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
     gene            complement(969..2603)
                     /gene="lnt"
                     /locus_tag="PK063_16705"
     CDS             complement(969..2603)
                     /gene="lnt"
                     /locus_tag="PK063_16705"
                     /inference="COORDINATES: protein motif:HMM:TIGR00546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016410 - N-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006497 - protein lipidation [Evidence
                     IEA];
                     GO_process: GO:0042158 - lipoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="apolipoprotein N-acyltransferase"
                     /protein_id="HMZ98743.1"
                     /translation="MTISRARLILLACASGFLYPLSFPAFDLGIVAWFALVPLHIAVE
                     YASPRRAFRVGWLAGTLAFTGAMFWVITAMNVYGKVPLPIAVLVMLLLTVYLGLYLAV
                     YAGALSWIRIAFPTLGFLPAPFLWVTLELIRTYFLSGLPWALFGYSQYQWLAIIQFAD
                     HFGVYGVSFLLVLVNAALAETLIWSFKAYRGFQIRSVPWPSLVAAASGFGVALFYGTS
                     VLSAAQHATPRMLSVGLVQPNVEQAQKWDVAFRQETMSRYDRLTTGLGENLDLIIWPE
                     AATPFVFEMEPQYRAIVNDMARRADAPLLFGSPALRRYPDGKPFLLNSAYLLATDGQI
                     LGRYDKQHLVPFGEYIPFHNSLLFFLDKLVEGIGDFEAGPGSTLLMFKPHEKTPPMTA
                     AASNADFHLKFGVVICYEVIFPNLVREFAANGADFMVTVTNDAWFGPSSAPYQHFGMV
                     VFRAVENHVAFARAANTGISGFIDPYGRVLQQSPIFTQEALRGTIPVSHQQTFYSQYG
                     DLFAYACAILIALLCLTGYFSPNAEPAGGEPAGRPA"
     gene            complement(2700..3098)
                     /locus_tag="PK063_16710"
     CDS             complement(2700..3098)
                     /locus_tag="PK063_16710"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98744.1"
                     /translation="MAIITTILLFVMWALISPRCDADAQSLPFRESHGTTGTLSPLGD
                     GSAIYSDPHGNTNPTQLGSGVPSHSFSGPHGATPGTLTPFGTPTPPNLLTPAPLLPLQ
                     PKGMAIPQPQSPASPSPPGRFAPPGGRPGR"
     gene            3596..4543
                     /locus_tag="PK063_16715"
     CDS             3596..4543
                     /locus_tag="PK063_16715"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98745.1"
                     /translation="MGRKYDLVDLMAAIGLVATLFGGYLLVTAADGFWQAPITPTMSS
                     VIASNEPSTGMQYLQPVLGQAIVQDLLLERDAGAALSTSAMELNRAVSESERISTTLL
                     SPLVLAELRAFGQDTDHRARMQYVMGKSVVNQTRRGISSGMLSADQYGGEFNTNLIRT
                     AELTGQRMHDQFEATRQPALGQSIIEAIQEEDRMTATAQERVGRAVVQVTQAQEHYAE
                     AKADRQIQLASATVAAVRTDALMDRLAILENMSADRTMIAHHRAASADVSRGSLILAC
                     VGLIALFVGGLAFSTRKGEVDSIPLWKLETLLQLHRSGR"
     gene            4598..4720
                     /locus_tag="PK063_16720"
     CDS             4598..4720
                     /locus_tag="PK063_16720"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98746.1"
                     /translation="MSWENWAVAIGLGALLMMFFGLMEMFFAGPRHPLDPSHRK"
     gene            complement(4724..5065)
                     /locus_tag="PK063_16725"
     CDS             complement(4724..5065)
                     /locus_tag="PK063_16725"
                     /inference="COORDINATES: protein motif:HMM:NF018894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HMZ98747.1"
                     /translation="MNASYRQRGTRRIPVQYPIYYSNGAFQTIGVTEDFNIEGGRVRG
                     REAVTVGMELVVIVIQAIPETPMLIRRATVRWSKGHDFGIALSGVPPQSEAELKAMAK
                     VMLPGLWSCLN"
     gene            complement(5062..5502)
                     /locus_tag="PK063_16730"
     CDS             complement(5062..5502)
                     /locus_tag="PK063_16730"
                     /inference="COORDINATES: protein motif:HMM:NF037970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HMZ98748.1"
                     /translation="MVFAAPIILSYMLLLVGLAVAAPGVGWGGSLIEFVPEAWRDGAH
                     VPAYGVFAWLVMWGLLRRGWPVTHATSIGILATGVFGLWTEVAQGTAPGREVSLHDVW
                     SDLLGSTIAAAFMLWREKAIRMSKGFMVGHKRSHHHLMKGTRSR"
     gene            complement(5678..6190)
                     /locus_tag="PK063_16735"
     CDS             complement(5678..6190)
                     /locus_tag="PK063_16735"
                     /inference="COORDINATES: protein motif:HMM:NF013412.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HMZ98749.1"
                     /translation="MPMPDAMRTEEVQAACDALVARVRTAVLLTLKQGHPFGSHVPYL
                     MGDDWSRVYLHLSGLASHTQHMLKDPRISLFIAEPDGAGKNPSALQRLNLQGSGAILS
                     PSHQSYDKVKERYLGQFPQSRMLFGFGDFAMWELHMSDAHLVLGFGHAYQAHSDNPRE
                     WQHQKPETKP"
     gene            6378..6779
                     /gene="bamE"
                     /locus_tag="PK063_16740"
     CDS             6378..6779
                     /gene="bamE"
                     /locus_tag="PK063_16740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamE"
                     /protein_id="HMZ98750.1"
                     /translation="MRHMQWGLALAGICVVIGLTGCGGKQAEIKEDRLTVGRVQGEVK
                     VGMSAAQVAELLGSPNIVTTDDKRREVWIYDKVSTDRVDTSSSSYAGLIILGANSSDH
                     SSSQRQRTLTIIIKYDEEKKVRDFAYNSTQF"
     gene            6817..7371
                     /locus_tag="PK063_16745"
     CDS             6817..7371
                     /locus_tag="PK063_16745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98751.1"
                     /translation="MILVLACGLFLGGCAEQTQPAQFFELSPESSANRAMQTRLFETG
                     ADNELLSASAASLQDLGFQIEESVREVGLLRAAKERSAREYGQYRNRFLIWLVSLGHL
                     VIPVDLHQKIAATIVIRPANHSDARQEVRIIFYRVIWKGDGQADRNYIPPGEQKMEMI
                     RDPEIYQQFFAKLSKAVFLEPHSI"
     gene            7384..7821
                     /locus_tag="PK063_16750"
     CDS             7384..7821
                     /locus_tag="PK063_16750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98752.1"
                     /translation="MNRTQFIGAVGIVAAALALHGCVAPEPRQELFAPTDAQMKIRSA
                     QSRTFEVTDSAVAMRGVIAALQDLGFIIERANAPLGLVTAARFAEPNYYDVLGVTVTV
                     RPQEAGKTMIRANAIYNSKPIEDPKVYQNFFAAVERSLFLVKD"
     gene            7825..8427
                     /locus_tag="PK063_16755"
     CDS             7825..8427
                     /locus_tag="PK063_16755"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98753.1"
                     /translation="MTGPRRSTLFSFRRSGGRPIVGSLALLAVLAGGCSPYEWRHENQ
                     WESRDQIWLSEASQVKVRAAQSRVFDGADRVKTIQAVVSTCQDLGFAVEVLDEALGIV
                     SAKKFDDYEPTRLRDPSYHLYRDDGLLILTPHFRSWGPFYHRSNLVRLTVTVRPRGEG
                     QLVVRASAQYYLKAIESPEPYQQFFRTLEQALFIQASTLP"
     gene            complement(8452..9162)
                     /locus_tag="PK063_16760"
     CDS             complement(8452..9162)
                     /locus_tag="PK063_16760"
                     /inference="COORDINATES: protein motif:HMM:TIGR02466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02466 family protein"
                     /protein_id="HMZ98754.1"
                     /translation="MPTEIEIQITPLFSTPLLVFTPADHTRINARLSTMILEREASVP
                     AHRDNEVVGWSSPHDLSMLEWAGEPLRDLFAPVLEVAKQVTTLSQRCGQGTGRPEWDV
                     VEVWANVQRNGGTNAAHSHPGSFWAGVYYVDVGEVSSNKDMGGELQIYDPRGCLPRML
                     APYLQYSMTELHDAGTSISYAPTSGQCVLFPGWLFHAVNTYHGKAPRISVAFNLDPVL
                     APGMMNGTQKRPITESRR"
     gene            9410..9613
                     /locus_tag="PK063_16765"
     CDS             9410..9613
                     /locus_tag="PK063_16765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dodecin family protein"
                     /protein_id="HMZ98755.1"
                     /translation="MSVARVTEIIAASPKSFDDAIHQGIARANKTLQHVKSAWIEDQK
                     VDIEDGKITQYRVALKVTFVLNE"
     gene            9623..9799
                     /locus_tag="PK063_16770"
     CDS             9623..9799
                     /locus_tag="PK063_16770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98756.1"
                     /translation="MKNVEMSVEGTWLTIKVDLSKEFGPSASGKTTIIASTEGNVTIT
                     GREEKIGLNVYRKK"
     gene            9988..11550
                     /locus_tag="PK063_16775"
     CDS             9988..11550
                     /locus_tag="PK063_16775"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ98757.1"
                     /translation="MLRTQPSALKVPTPAILIVDDDPDIALVLKDLLEHSGYQVQVAV
                     TGAEALTRAKTDSFSAVLLDLMLPDMDGLSVLTLLKGIDPALPVIMLTAFVEVAKKHA
                     SLTEGAFGYLTKPYDGEELKALIKRAVGVKHLSLEAASAKQALTASEDRFREVVQTAP
                     DAIVLADGEGRILSWNSAAERLFGYRAEEVLDRSLTMIMPERYRDNHERALERVRTTG
                     DVRLKGTVVTMHGLHKDGREFPIEMSLSSWISSGTRVHCGIVRDITARKEAEARLLQQ
                     QIEQQALLDLIPAMVWYKDSHNRILRANRRAAESIGKTVADIEGRSTDEFYPEDAERY
                     HQDDLEVIVSGRPKLGIIEPHRAGGKKHWVQTDKVPYLDPAGKVIGVLVFAQDITDQK
                     RHEAALRENQDLVRIVMEATGDGIVIVDGDGNILAVNTRVAELFGYASGDLTGQSLQR
                     LIPSLFNFGTFELASDRGASTKGESLPLNPTCVGLHKDGAEIAVSISSTMLMTANGAH
                     GVVAVHPLGGPG"
     gene            11547..12020
                     /locus_tag="PK063_16780"
     CDS             11547..12020
                     /locus_tag="PK063_16780"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98758.1"
                     /translation="MNLRFAFIILVLAFIALLLAIGVLTAIRWLRIHYPERANAILAA
                     SAVIVAGAVIMTIIEMNDRPMFRPHDLITLQEPVVARTIPGDRGAGSATCVIDLHEHL
                     GVLEIEIERGALKARVESNNTSAPVFCPIGTEVRIDLNWLHRLTITRRQTQVSGP"
BASE COUNT         2614 a         3375 c         3787 g         2454 t
ORIGIN      
        1 aggcgatatc ttttttctcg ccgacaatcg cgttgaactc ggcttccttc ttgcgctgtt
       61 ccacttcaaa gagacgggcc ctcaatattt tcatggctcc attacggttt tggagctgag
      121 accgctcgtt ttgacattgc accacgatgc cggtcggaat gtgtgtgatg cgaatggccg
      181 tctcaacttt gttcacattc tggccgccgg cgccgccggc ccggaacgtg tcgactcgca
      241 ggtccttatc ctcaatgacc acctctacgt catcgtcgag ctccggatag acgaacaccg
      301 aggcgaaaga ggtgtggcgg cgtttgttcg cgtcgaacgg cgaaattctc accaggcggt
      361 gaacgccggc ctcagccttc agatagccat aggcataggg gccgttgacc gacaaggtcg
      421 cgctcttgat gccggcctct tcccccgcct gtaagtccaa tgtctcgatc ttgaatccct
      481 tctgctcggc ccaccgcacg tacatccgca ggagcatttg cgcccagtct tgcgactcgg
      541 tgcctccggc cccgggatgg atggcgaaga tcgcgttgtt ggcatccaac tcgccggaga
      601 gcagcaactc gatgcggaac tgggcgacgg ctttttcgaa gggctcgagt tcggccgtca
      661 gttcctgctc caatgcggcg tcgccagact ccaaggccaa ctcgaggagc gcctcgatat
      721 cgctctgacg gcgttcggtg tcgcgccagc gtgaaagttc ccgatccagg gcggccttgc
      781 gacgattcac cttggcggca gcctgcgtat ctttccagaa atccggctgg gaggttttga
      841 cgtcgatgtc gttgagttca gcggtcatcc gagccaggtc aaagatgccc ccgtagctgc
      901 gctaactgtt caccaagggt tcgcacgcgg gtccggacat catccaacat ggcacggtcc
      961 tttctctctc aggctggtcg cccggcaggt tcgccgccgg ctggttcggc attaggcgag
     1021 aagtagccgg tcaggcacaa aagcgcgatg agtatagcac aggcataggc aaagagatca
     1081 ccgtattggg agtaaaaggt ctgttggtga ctcacgggaa tggttccacg caacgcttct
     1141 tgcgtgaaga tgggagattg ttgcagcacc cggccatacg ggtcgatgaa gccggaaatg
     1201 ccggtattgg cggcccgcgc gaaggccaca tgattctcca cggcgcgaaa gaccaccatg
     1261 ccgaaatgtt gatagggagc tgacgagggg ccgaaccagg cgtcattcgt gacggtcacc
     1321 atgaagtctg ccccgttggc ggcaaactcc cgcacgagat tggggaagat cacctcataa
     1381 caaatgacca cgccgaattt tagatggaaa tccgcgttgc tggccgcagc ggtcatgggt
     1441 ggagtttttt catgcggctt gaacatcaac agcgtcgagc ccggaccggc ttcaaaatcg
     1501 ccgatgcctt ccaccagctt gtcgagaaag aacagcagag agttgtgaaa cggaatgtat
     1561 tccccgaagg gcacgagatg ttgtttatcg tatcgcccga ggatttggcc atcggtcgcc
     1621 agcaggtacg cgctattcag caaaaacggc ttgccatccg gataacgccg tagtgccgga
     1681 ctgccgaata acagcggggc gtcagcgcgc cgtgccatat cgttgacgat ggcccggtat
     1741 tgcggctcca tctcgaagac aaagggcgtg gcggcttccg gccaaatgat gagatccaga
     1801 ttctcaccca acccggtggt caaccgatca tagcgggaca tggtttcctg gcggaacgcc
     1861 acatcccact tctgtgcctg ttcgacgttc ggctgaacca gaccgacgga cagcatgcgg
     1921 ggtgtggcat gttgcgcggc ggacaggacg ctcgtgccgt aaaagagtgc cacgccgaat
     1981 cctgaggcgg ctgcaaccag tgagggccag ggaacggaac ggatttgaaa tccccgatag
     2041 gctttgaaac tccaaatgag tgtttccgcc agcgcggcat tgaccagcac gagcaggaac
     2101 gacaccccat acactccaaa atggtcggcg aattgaatga tggcgagcca ttggtactgg
     2161 gaataaccga acagtgccca gggtaacccg gagagaaaat aggtccggat caattcgagc
     2221 gtcacccaca ggaagggcgc cggcaggaat ccgagcgtag ggaaggctat tctgatccag
     2281 gacagcgcac cggcatagac agccagatag aggccgagat acaccgtgag caataacatc
     2341 accaggacgg caatcggcag cggcaccttg ccatacacat tcatggcggt gatcacccaa
     2401 aacatggcgc cggtaaaggc cagggtaccg gcgagccatc ccacccggaa ggctcgccgt
     2461 ggcgaggcat actccacggc gatgtgcaga gggacgaggg caaaccaggc cacgatgccg
     2521 aggtcgaatg ccggaaatga cagggggtag agaaaaccgc tcgcgcaagc aagcagaatg
     2581 aggcgtgcgc gggagatggt cattagccgt aacttaacga aagccttgag tagattcaac
     2641 agtcctgttt gggcgaatgc gtttgtatcg ccttgatctg cagttcacca ctccgtggat
     2701 taccgcccgg ggcgtccgcc tggtggagcg aagcgaccag gaggagaagg ggaggcaggc
     2761 gattgcggct gcgggatagc catgcctttg ggctgtagcg ggagcagagg ggccggtgtg
     2821 agcagattcg gcggggtggg cgtaccgaaa ggcgtcagcg tccccggcgt ggctccatgc
     2881 ggtccgctaa aactgtgaga gggcacgccg gatccgagct gcgtcggatt cgtattgccg
     2941 tgtggatcag agtagatggc gctgccgtcg cccaagggag agagcgtgcc ggtggtgcca
     3001 tgtgattctc gaaacggaag ggactgcgca tcggcgtcgc agcgtggcga gatcaatgcc
     3061 cacatgacga acaacagtat tgtcgtgatg atcgccatgc aacgcctctc acaaggagac
     3121 caggcacata taccgtagac atcctaccag acggcgaagg tccgatggga acgacacgta
     3181 agaagagcgc aggcattcct cgatggctgg caggccgcgc cggtgctcgc tttttcccgt
     3241 cttgaccgat gttttcttgg agcgtagact gattgcatct taggcagtac caccctttcg
     3301 gcaggtggtc acatggtctc ccgtggcata catgaccgcg gcaatgacca agccagtctt
     3361 gtccctttcc tccctcaggt tcccccgcgc gttaatatct cctggcaggt acgtacgagc
     3421 gtcttcgtct gtgccatgcc gaaggcatac atgcagggag cgcaggtatc acctttttca
     3481 aaggaggcct ctttatgcac agacgacagg gatcccgtgc cgttctaccc acggcgtgcc
     3541 ggcatcctgc ctgtttgccc cgcgccggat tacctgaggc aggaaggagg gtgtcatggg
     3601 acgcaaatat gacctcgtgg atctaatggc agcgatcggg ttggtggcca cactattcgg
     3661 agggtatctg ctcgtgacgg ctgccgatgg attttggcag gctccgatca ctcccaccat
     3721 gagcagtgtc atcgccagca atgaaccatc caccggtatg cagtatcttc aaccggtgtt
     3781 agggcaagcg atcgtgcaag atctgttgct ggagcgtgat gccggcgcag ccttgtcgac
     3841 ctctgcgatg gaattgaacc gcgctgtcag cgaatctgag cgaatctcca ccacgttgtt
     3901 aagtccgctc gtgctggcgg aattgcgcgc cttcggacag gacactgatc accgcgcgcg
     3961 catgcaatat gtcatgggca agtcggtcgt caaccagacg cgacgtggca tctcgagtgg
     4021 gatgctttcc gctgaccagt atggcggcga attcaatacc aatctgatca ggacggcgga
     4081 attgaccggg cagcggatgc acgaccaatt cgaggccacg aggcagccgg cgctggggca
     4141 gtcaatcatc gaggccattc aagaggaaga ccggatgacc gccacggctc aggaacgagt
     4201 cggacgggcc gttgttcagg tcactcaggc tcaggaacac tatgcggaag cgaaggccga
     4261 ccggcagatc cagttggcga gcgcgacggt tgcggcggtg cggaccgatg cgttgatgga
     4321 ccgattggcg atcctggaaa acatgtcggc tgaccggacg atgatcgctc atcatcgggc
     4381 tgcgagcgcg gacgtttctc gcggctccct gattctggct tgtgtcgggc tgatcgccct
     4441 gttcgtgggt ggattggcgt tcagcacccg aaagggcgag gtggacagca tcccgctctg
     4501 gaagctcgag acattactgc agttgcatcg atcgggaagg taggctgatc accctgggaa
     4561 tcgatgggcg attcccaggg tgtgagagga gaccattatg tcgtgggaga actgggctgt
     4621 ggcgatcgga cttggcgcgc tcctcatgat gttcttcggc ttgatggaga tgttttttgc
     4681 cggtccgcgg catcctttgg atccgtcgca ccggaaatag cgttcagttc aggcaggacc
     4741 agaggcccgg caacatcact ttggccatgg ctttaagttc ggcttccgat tgaggcggga
     4801 cgccggacag ggcgatgccg aagtcatggc ctttcgacca acgcacagtt gcgcgacgga
     4861 tcagcatcgg ggtttcaggg atcgcctgaa tcacaatgac caccagctcc attccgaccg
     4921 tcacggcttc tctcccgcga acacgccccc cttcgatgtt gaagtcttcg gtcacgccga
     4981 tggtttgaaa cgcgccattc gaataataga tcgggtattg cacgggtatg cgtctggtgc
     5041 cacgttggcg atacgaagcg ttcatctcga ccttgttcct ttcatcaggt ggtgatggct
     5101 cctcttgtgc cccaccatga aacctttcga catcctgatc gccttttcac gccacagcat
     5161 gaacgcggcg gcgatcgtgc ttcccagcag gtcactccac acatcatgga gggacacttc
     5221 tcgtccagga gctgtgccct gcgccacttc cgtccagagg ccgaatacgc ccgttgccag
     5281 gattccgatg gaagtcgcat gagtgacggg ccacccgcgg cgaagcagtc cccacatgac
     5341 taaccaggca aataccccgt aggccggcac gtgtgctcca tcacgccagg cttcgggtac
     5401 aaattcgatg agagaaccgc cccaaccgac gcccggggcg gccacggcaa gcccgaccag
     5461 caacagcatg taactcagga tgatgggagc ggcaaatacc atgtagggga caactccggt
     5521 gagctcacgt gactctgcgc agagtactgt gcaggacgcg gagcgcacca tcggtccttc
     5581 ggccaagtgg gtagtgcttt ggaggggaga gcgcccgctg gagtgtcagc ctcgaggtag
     5641 ggctagatca gagaaaaaac ggccgggatg cgatggctca gggtttcgtt tcaggcttct
     5701 ggtgctgcca ctcccgcgga ttgtcagagt gggcctggta ggcatggccg aatccgagca
     5761 ccaggtgggc gtcactcatg tgcagttccc acatagcaaa atcgccgaag ccaaacagca
     5821 ttcgggattg tggaaattgt cccaggtacc gctccttcac cttgtcatac gactggtggg
     5881 acggcgagag aatggcgccg ctaccttgga gattgaggcg ttgcaacgct gacgggtttt
     5941 tcccggctcc gtccggctcg gcaataaaga gactaatgcg tgggtctttc agcatatgtt
     6001 gggtgtgcga ggcgagaccg ctcagatgaa gataaacccg ggaccaatcg tctcccatca
     6061 gataggggac atgagagccg aaggggtggc cctgtttgag ggtcaacagc acggcggttc
     6121 gtacccgcgc gacaagtgca tcgcacgcgg cctggacctc ttccgtccgc atggcatctg
     6181 gcatcggcat aggcattgac cgccctccct acgaccattg tagctgctgc tgatcaattg
     6241 tccagccatc tgacaatgga ggcagtcgtc ggccggacgc tcctggcgaa tcacgctttg
     6301 cgtccgggat ggacgcgagc taagatgtgc ccctggcgat aacgtagagg atgatgtgaa
     6361 aaatggagac gcagaccatg agacacatgc aatggggatt ggccttggca ggtatctgtg
     6421 ttgtgatcgg tttgactggt tgcggcggga agcaggccga aatcaaggaa gaccggttga
     6481 ccgtggggcg tgtgcagggg gaagtgaaag tcggcatgtc cgcggcgcag gtggcggaac
     6541 tcctgggctc gccgaacatc gtgaccaccg atgataagcg gcgcgaggtg tggatctatg
     6601 acaaggtgtc gacggatcgt gtcgatactt cgagctcctc ctatgccgga ttgatcattc
     6661 tgggcgccaa ctccagcgac cactccagct cccagcgcca gcgcacgctg accatcatca
     6721 tcaagtatga cgaagagaaa aaggtcagag actttgccta taactcgact caattctaag
     6781 cggtctgacg ctggcagcgg acgcgggtgg gctgccatga tcctggtgct tgcctgcggg
     6841 ctgttccttg gcggctgcgc ggagcagacc cagccggcgc agttttttga actctcgccg
     6901 gagagcagcg ccaatcgggc gatgcagacg cggctattcg agaccggggc ggataatgaa
     6961 ttgttatcgg cctcggccgc ctcgctgcaa gatctcggct ttcagataga agagagcgtg
     7021 cgagaggttg ggcttctgcg cgcggcgaaa gagcgaagcg cccgggagta cggtcagtat
     7081 cgcaaccgct tcctcatctg gctggtgtcg ctggggcacc tggtgatccc cgtcgattta
     7141 catcaaaaaa ttgcggcgac gattgtcatc cgtccggcaa accacagtga tgcgaggcag
     7201 gaagtccgga tcatcttcta tcgggtgatc tggaaggggg atggccaagc ggaccgcaac
     7261 tatattccac ccggggagca gaagatggaa atgatccgcg atccggaaat ttatcagcaa
     7321 ttctttgcga agctttccaa ggccgtcttc ttggaacccc attcgattta acggcgaggg
     7381 tacatgaatc ggacacaatt catcggagcg gtgggaatcg tggcagctgc cctggcgctg
     7441 cacggctgtg tggctccgga gccgaggcaa gaattattcg cgccgaccga tgcgcagatg
     7501 aaaatccgga gtgcgcagag ccgcacgttc gaggtgactg attctgccgt ggccatgcgc
     7561 ggggtcatcg cggctttgca agatttggga tttattatcg aacgtgccaa cgcaccgctc
     7621 ggtctggtaa ccgcggcgcg ttttgccgaa cccaattatt atgatgtcct gggagtgacg
     7681 gtgacggtga ggccccaaga agccggcaag accatgatcc gggccaatgc gatctataac
     7741 agtaagccga tcgaggaccc gaaagtttat cagaactttt ttgccgcggt ggagcggtca
     7801 ttgtttctgg tgaaggacta gcgcgtgacc ggtcctcgtc gctcaacgct gttctcattt
     7861 cgccggtctg gcggtcggcc gatcgtgggg agcctcgcgc tcctagcggt gctcgcgggg
     7921 ggctgttcgc cctatgagtg gcgacatgaa aatcaatggg aatcgcgtga ccagatctgg
     7981 ctctccgagg cgagccaggt caaggtacgg gcggcgcaaa gccgggtatt cgacggggcg
     8041 gaccgggtca agacgattca ggccgtggtc tctacctgtc aggatctggg gtttgccgtc
     8101 gaagtgctgg atgaggctct gggcatcgtt tcggcaaaga agttcgatga ttacgaaccg
     8161 acccgattaa gggacccttc ctaccatctc tatcgagacg acgggctgct gattctcact
     8221 ccacacttcc gtagttgggg accgttttac caccggagca atctggttcg tctcaccgtc
     8281 accgtgcgac cacgtggaga gggccagttg gtcgtgcggg ccagtgccca gtattatctg
     8341 aaggcgattg aatcgcccga accctaccag caattcttcc ggacattgga acaggcgctg
     8401 ttcattcagg cgagcacatt gccgtagccg gaacgatcat caacgggtgc attatcggcg
     8461 ggattcggtg ataggacgtt tctgtgtgcc gttcatcatg ccgggcgcga gaaccggatc
     8521 gaggttgaat gccacactga tgcggggggc ttttccatgg taggtgttca cggcatgaaa
     8581 gagccagccg ggaaacagta cacactgtcc cgacgtggga gcataagaga tgctggtccc
     8641 tgcatcgtgc aattcagtca tgctgtactg aagatacggc gctagcatac gcggcagaca
     8701 cccgcgtggg tcgtagattt gtaactctcc tcccatgtct ttgttggaag aaacctcccc
     8761 gacatccaca tagtacaccc cggcccaaaa actaccgggg tgggaatggg ccgcattggt
     8821 gccgccgttc cgctgcacat tggcccagac ttctacgaca tcccactccg gtcgaccagt
     8881 accctgtccg cagcgctggg ataaggtggt gacctgtttc gccacttcca acaccggagc
     8941 aaacagatcg cgtagcggtt cgccggccca ttcgagcatg gacagatcgt gaggcgatga
     9001 ccagccgacc acttcgttat ctcgatgggc cgggacggac gcctcccgtt caagaatcat
     9061 ggtcgagagc cgggcgttga tgcgtgtatg gtcagcggga gtgaatacca gcagaggcgt
     9121 ggaaaataga ggggtgattt gtatctcgat ctcggtcggc atggatggtg tcccatactg
     9181 atctacgacc gcggatgggt gcacggtata tccccgttac aacgcaagtc aacctagagg
     9241 tttacccagg gagagcgggg aaggctttcc cggcaaaatt ggaggcagct gtggcagaaa
     9301 tccagatgct gcctggttca agacgggggt ggctccttga cagggctttg ccgtcggcct
     9361 agcctgaggt gaccaggatc catcgaactc tataaccagg gaggctatca tgtctgttgc
     9421 ccgagtgacg gaaatcatcg ccgcatcccc gaagagtttt gacgatgcca ttcatcaagg
     9481 tattgcccgc gccaataaga cgttgcagca tgtcaagagc gcgtggatcg aggatcaaaa
     9541 agtggatatc gaggatggaa agatcacgca gtatcgggtg gcgttaaaag tgacgttcgt
     9601 gcttaacgaa taaggacgca ttatgaaaaa tgtcgagatg tccgtcgagg gaacctggtt
     9661 gaccatcaag gtggatctat caaaggagtt cggcccgtcc gcgtcgggga agaccaccat
     9721 catcgcgtcc acagaaggga atgtcaccat cacggggcgg gaggaaaaaa tcggcctcaa
     9781 tgtctatcgg aaaaaataga ggcgcgggtg cctgaccacg actgttccgt ccatgagggg
     9841 gagagacgaa gaacctgcgt gtgacaacaa cgcacctgag aggggcaatt ccggctaacg
     9901 gtctggattc ctgtcgtcaa aaagaggaca ataccgttca gtgcgggaac cggatcgtac
     9961 cagaaccctt gggcttcgtt gaccgccatg ctgagaaccc agcccagtgc cctcaaggtg
    10021 cccactcccg cgattctcat cgtggacgat gatcccgaca ttgcgcttgt cttgaaagac
    10081 ctcctcgagc attccggata tcaggttcag gtcgccgtca ctggtgcgga agcgctgacc
    10141 agggcgaaga cggactcgtt ctcggcagtg ctcctcgatc tcatgttgcc cgatatggac
    10201 ggcctttcag tgctgaccct gttaaagggc atcgacccgg cactgccggt gatcatgctg
    10261 acggcgttcg tggaggtagc caagaaacac gcgtcgctca ccgagggggc cttcggctat
    10321 ctcaccaaac cgtatgacgg cgaggaattg aaggccctga tcaagcgggc cgtcggggtc
    10381 aagcacctgt cgctcgaagc cgcttcggcg aaacaggcgc tcactgccag cgaggaccgg
    10441 tttcgcgaag tcgtgcaaac cgcgccggac gccattgtgc ttgcagatgg ggaagggcgt
    10501 attttgtcat ggaacagtgc ggcggagcgg ctattcgggt atcgtgcgga ggaagtcctg
    10561 gaccggtccc tgaccatgat catgcccgaa cgatatcgcg acaatcacga gcgggctctc
    10621 gaacgggtgc gcaccaccgg cgatgtgcgc ttgaagggga ccgtcgtcac catgcatggc
    10681 ctgcataagg atggacggga atttcccatt gaaatgtcgc tgagtagttg gatttcaagc
    10741 ggtacccgag tgcactgcgg tattgtccgg gacatcaccg cacggaaaga agcggaagca
    10801 cgcctgctcc agcagcagat cgagcaacag gcgctgttgg atctgatacc agccatggtg
    10861 tggtacaagg attcccacaa tcgcattctg cgggccaacc ggcgagcggc cgagtctatc
    10921 gggaaaaccg tggcggacat cgaagggcga tcgaccgatg agttttatcc ggaggacgcc
    10981 gaacggtatc atcaggacga tttggaagtc atcgtgtcag gtcgaccgaa actcggcatc
    11041 atcgagccgc atcgagcggg agggaagaag cactgggtgc aaacagacaa agtaccctac
    11101 ctcgacccgg cgggaaaggt catcggtgtg ctggtcttcg cgcaggacat cacggaccaa
    11161 aagcgtcatg aagccgcgct tcgcgagaat caggatctcg tgcggatcgt gatggaagcc
    11221 accggcgacg gcatcgtgat tgtggatggc gacgggaata ttctggccgt gaatacacgg
    11281 gtggcggagt tattcggtta tgcctcaggc gatctgacgg ggcaatcact ccagcggctc
    11341 attccttcac tcttcaattt tgggacattc gagttggcgt ctgaccgcgg cgcttcgacg
    11401 aagggagagt cgttaccgct caacccgaca tgcgtcggcc tgcataagga cggcgcagag
    11461 attgccgtct ccatcagctc gacgatgctg atgacggcaa atggagcgca tggcgtcgtt
    11521 gccgttcacc ccctgggcgg ccccggatga acctgcgctt tgcgttcatc atcctggtgc
    11581 tggcgttcat tgcactgctg cttgccatcg gcgtcctgac ggctattcga tggctcagga
    11641 tccactatcc cgagcgtgcc aacgccatcc tcgcggcaag cgcggtgatt gtcgccgggg
    11701 ccgtcatcat gaccataatc gaaatgaacg atcggccgat gttccggccg catgatctca
    11761 tcaccttgca agagccggtc gtggcacgaa cgattcctgg cgatcgcggg gcgggcagcg
    11821 ccacctgcgt catcgacctg catgaacatc tgggcgtgtt ggagattgaa atcgagcggg
    11881 gcgcgctgaa ggcacgggtc gaaagtaaca atacctccgc gcctgtgttt tgcccgatcg
    11941 gcacagaagt gcgtatcgac ctgaactggc tgcatcgtct gaccatcact cgccggcaaa
    12001 cgcaggtgag cgggccgtag ctaccccctg cgcgctcttg actgatcgag gtggagaggc
    12061 ctatcgtacc cgagtggggg gagttaacgc cccgggggaa tatgtacaaa aaggggattg
    12121 agtgttgagg atggtgtgca tgcccggctt gtaccgggaa gcctgaagtc ctcccgagat
    12181 ctccgccgta tctacctctc ctcggtaggt gcgtcctcct cccacccaaa
//
LOCUS       DAOQPD010000100        12052 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_2703_length_12052_cov_23.767108, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000100 DAOQPD010000000
VERSION     DAOQPD010000100.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 12052)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 12052)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12052
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2703_length_12052_cov_23.767108"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            43..441
                     /gene="rplL"
                     /locus_tag="PK063_16785"
     CDS             43..441
                     /gene="rplL"
                     /locus_tag="PK063_16785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014961308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HMZ98759.1"
                     /translation="MSAAGTKLSQDELIKAIEGMSVLELAELVKGLESRFGVTAAAPV
                     AVATVGGGGAAAAPAEEKTSFDVILASAPADKKIQVIKVVRELTSLGLKEAKDLVEGA
                     PKPIKAGATKEEADTMKKKLEESGAKVEIK"
     gene            523..4482
                     /gene="rpoB"
                     /locus_tag="PK063_16790"
     CDS             523..4482
                     /gene="rpoB"
                     /locus_tag="PK063_16790"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000345 - cytosolic DNA-directed RNA
                     polymerase complex [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HMZ98760.1"
                     /translation="MSESTLSEFVERKDFSRIRTSIDIPDLIEIQKRSYEEFLQMEVE
                     PDRRKDQGLQAALASVFPITDYNNTAALEFSNYSLGTPKYDERECLEQGMTFAVPLKL
                     RVRLIVFDKEDKGPKKKVLDVREQEVYVGELPLMTERGTFLINGTERVVVSQLHRSPG
                     ASFTHDKGRTHASGKVLYSARIIPYRGSWLDFEFDARDILYVRIDRRRKMPATILLKA
                     FGYSTDDLLRMYYPVEEIRVSKGKLFRKLDPEIHHGLKCSTEVMEKGGKDPIVREGAK
                     LTKVLIAKLKAAGIKEIPVTPAELVGRAVLTDLVDGGKKQALAEKNQRLTEEILEKIL
                     DSDIEEFKVIYLDTTNATLVILDTLDMERTGSKEEAMVEIYRRLRPGETPSVETARAL
                     FDNLFLSPKRYDLSPVGRLKLNKKLGLDFALEQRTLTAQDIVEVVRYLVNLKIGRGEI
                     DDIDHLGNRRVRSVGELLENQFRLGLVRMERSIKERMNLLDMETVLPHDLINAKPVVA
                     AVKEFFSSSQLSQFMDQTNPLAEITHKRRLSALGPGGLTRERAGFEVRDVHPSHYSRI
                     CPIETPEGPNIGLITSLATYARINEFGFIEAPYRKVVKGRVSDELEYLSAIEGDKYII
                     AQANSKVDGSNRLVSETVSARSAGDFITATPDKIEYMDVSPKQVVSVATALVPFLEHD
                     DANRALMGSNMQRQAVPLLKAESPLVGTGMEAVVARDSGYVVQAKREGVVESVDATRI
                     VVRADAKEGRKRNDSGLDVYEMIKFQRSNQNTCITQTPVVRIGEPVKRGQVLADGPAI
                     DHGELALGKNVLVAFMPWGGYNFEDAILLSEKLVREDAFTSIHIEEFEVEARDTKLGK
                     EDITRDIPNVGEEALRDLDESGIIRIGAEVKPGDILVGKVTPKGETQLTPEEKLLRAI
                     FGEKAGDVKDTSLTVPPGVEGIVVDVKIFSRKGLDKDERSKSIESEDHMKLQRDHQEE
                     LRIIEDEKTKKVRKLLLGKVVGRDLMDPETGDVILKKKGKLTAEILKRLPDDMVRHII
                     LSDPDEQKELEDVERRAKEQIEILQTLYDEKVGRLRRGDELPPGVIKLVKVYIAMKRK
                     IQVGDKMAGRHGNKGVVSRVLPEEDMPYLPDGTPVEIVLNPLGVPSRMNVGQILETHL
                     GWAARALGIKVASPVFDGASEKEIKELLKKAKLSPSGQTVLMDGRTGESFSSPVTVGY
                     MYVLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRLGEMEVWALQAYGAASIL
                     QEFLTVKSDDVPGRSRMYEAIVKGEPFLEPGLPESFNVLVKELQSLGLDVELVKSKD"
     gene            4624..8754
                     /gene="rpoC"
                     /locus_tag="PK063_16795"
     CDS             4624..8754
                     /gene="rpoC"
                     /locus_tag="PK063_16795"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000345 - cytosolic DNA-directed RNA
                     polymerase complex [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HMZ98761.1"
                     /translation="MRIRIASPEKIRSWSYGEVKKPETINYRSFKPEKDGLFCAKIFG
                     PIKDWECNCGKYKRMKHRGIVCDKCGVEVIQSKVRRERMGHIELAAPVAHIWFLKGVP
                     SRIGTLLDMSLKQLEKILYFESYVMVDPGSTSMSEQELVSEEQLRSLQSEYGSGAFKV
                     GIGAEAIRELLRKVDINTQWDELHVKAKASASAALKKKYAKRLKVLEAFRRSGNKPEW
                     MIMDVIPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELKAPGVIIRN
                     EMRMLQEAVDALFDNGRRGRAIRGPNKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGR
                     TVIVVGPELRLHQCGLPKKMALELFKPFIFHKLEERGAATTIKSAKRLVEKERPEVWD
                     VLDEVIREHPVLLNRAPTLHRLGIQAFDPVLVEGKAIRLHPLVCAAFNADFDGDQMAV
                     HVPLSVEAQVEARVLMMSINNILSPANGKPIAVPSQDMVLGCYWLTKERVGAKGEGKL
                     FGSPEEARIAYDAGALDEHARIKVRCNGTLVQTTAGRVILSEILPPMMPFADANKLMT
                     KKEMSKLIDAVYRQAGHRETVTFLDKIKDLGFHYATRAGMSICIDNMHIPSRKEDLIG
                     KAQHEVNEIEKQYSEGLITNGERYNKVIDIWAHVTEQVANEMMKELGAGGDPAKAESF
                     NPIFMMADSGARGSSQQIRQLGGMRGLMAKPSGEIIETPITANFREGLTVLQYFISTH
                     GARKGLADTALKTANSGYLTRRLVDIAQDVIVTEEDCGTTDGILVSALLEGGEIIQPL
                     EERLLGRLAGEDIRDPVTGEIIVSFNEEIDEEQAKAVVEAGVDRVKIRSVLTCQSARG
                     VCRLCYGRDLSRGRLVEKGEPVGVIAAQSIGEPGTQLTMRTFHIGGTASKVVEQTVLE
                     AKHAGHLKYMSLDAKKNADVHNAGIAVRNKEGEWVVMNRNAKIAIVDDSGREREKYPV
                     VYGAKIKLKDGDRIEVGQKLVEWDPYSLTILTETGGKVAYGDILEGVTMKEEFDEVTG
                     LSRKVIIEQSGATLRPRVSIKDDSGKTAKVSGAGAPVARYLLPVGAHIFVEKGAMVHP
                     GDVLAKIPRETTKTKDITGGLPRVAELFEARKPKEQAVISEIDGEVSYGGFVKGMRKV
                     LVDNKMGDVKEYFIPKGKHVNVHEGDWVRAGEPLMDGSANPHDILDVLGPKELQKYLV
                     DEVQDVYRLQGVSINDKHIEIIVRQMLRKVRIEDPGDTSFLPGSQVSKGMFDVENQRV
                     LEKDGKPALGKPVLLGITKAALTTDSFISAASFQETTRVLTEAAINGREDNLLGLKEN
                     VIVGRLIPAGSGFEEYRETFVASAKAPGELSGDQSQPVAVGQAPITSVGSASENNA"
     gene            8862..9233
                     /gene="rpsL"
                     /locus_tag="PK063_16800"
     CDS             8862..9233
                     /gene="rpsL"
                     /locus_tag="PK063_16800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018003268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HMZ98762.1"
                     /translation="MPTINQLVRKGRTLVKSKTKSPALKRCPQKRGVCLRVYTTTPKK
                     PNSALRKVARVRLTNGMEVTTYIPGVGHNLQEHSIVLVRGGRVKDLPGVRYHIVRGSL
                     DAVGVADRKQARSKYGAKRPK"
     gene            9296..9769
                     /gene="rpsG"
                     /locus_tag="PK063_16805"
     CDS             9296..9769
                     /gene="rpsG"
                     /locus_tag="PK063_16805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002006497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HMZ98763.1"
                     /translation="MPRGQFFGHREAQPDSKYRDKLVGKFLNVLMGGGKKSTAERICY
                     GAFDLIQEKTNGGDPMKIFKSAIDNVKPVVEVKSRRVGGASYQVPVEIRPSRRVSLAL
                     RWITEYSRSRGGKSMQDRLAAELLDASNNTGASVKKREDVHRMAEANKAFAHYRW"
     gene            9883..11964
                     /gene="fusA"
                     /locus_tag="PK063_16810"
     CDS             9883..11964
                     /gene="fusA"
                     /locus_tag="PK063_16810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HMZ98764.1"
                     /translation="MARQTPLERTRNIGIMAHIDAGKTTTTERILFYTGMTHKMGEVH
                     EGAATMDWMEQERERGITITAAATTCFWRDHRINIIDTPGHVDFTIEVERSLRVLDGA
                     VAAFDSVQGVEPQSETVWRQADKYEVPRIAFMNKMDRIGADFYASVQSIIDRLGANPV
                     PIQIPIGREAEFRGSVDLISMKGYFYDDETLGAKYKIGEIPADMVDQANDYRQKMLDA
                     VVEFDDQVMEKYLNGQSLAEDEVRRVVRAGTIAMKIVPVICGSAFKNKGVQQLLDAVV
                     DFLPSPVDIPPVIGVDPATGKDVERSPSDTEPFSALAFKIMTDPFAGQLTFFRVYSGT
                     LKTGTPVLNVTKGTKDRVGRLLKMHANKREEIEIVYAGDIAAAVGLKSATTGDTLADE
                     KQPVLLEIMKFPEPVIAMAIEPKTKPDQEKMGFALQKLAQEDPSFRVRTDEETAQTII
                     AGMGELHLEIIVDRLMREFKVEANVGKPEVAFRETIRRKAEAESKYIKQTGGRGQYGH
                     VVMTVEPSEPGKGLEFVNKTVGGSIPKEYIPAIEKGVKERMETGVVAGFPLRDVKVTV
                     IDGSYHDVDSNEMAFKIAASMGFADACKKADPVLLEPIMKVEVLVPQDFMGDVIGNLN
                     GRRGKVQGMKVRAGAQAIEATVPLMEMFGYATDLRSRTQGRATYSMEFDRYDQVPRQI
                     AEAITAKHRGE"
BASE COUNT         2804 a         2829 c         3761 g         2658 t
ORIGIN      
        1 gtcattgcag ccattcagga taaaaagaaa ggggagggcg acatgtcagc agcaggaacg
       61 aaattgtcac aggatgaatt gatcaaggca atcgagggca tgagcgtgtt ggagttggcg
      121 gagttggtga aggggctgga gtcccgcttc ggcgtgacgg cggccgcacc tgtggctgtt
      181 gcgaccgtgg gcggtggtgg tgcggcggca gctccggctg aagagaagac gtctttcgac
      241 gtgattttgg cgagcgcccc tgcggacaag aagattcagg tcatcaaggt ggtgcgtgaa
      301 ctcaccagcc tcggtctgaa ggaagcgaag gatctggtcg aaggtgcgcc aaagcccatc
      361 aaggcgggtg cgaccaagga agaggccgac accatgaaga agaagctcga agagagcgga
      421 gccaaagtcg aaatcaagta gtcgtgtgtg tgtctgcggt gtgagttgtc cgtcgggatg
      481 gcgcggggcg ttcatctcct tatgagcttg gagggctaac gaatgtcgga atcgactctt
      541 tcggagtttg tcgaacgtaa ggatttttct cggattcgca cgagtatcga tattcccgat
      601 ctcatcgaaa tccagaagcg atcctacgaa gagttcctcc agatggaagt cgagcccgac
      661 cgtcgcaagg atcaagggtt gcaggcggcg ttagccagcg tctttcccat caccgactac
      721 aacaacactg cggcgttgga gttttcaaac tactcgttgg gaactcccaa gtacgatgag
      781 cgggaatgtc ttgagcaggg aatgaccttt gccgttccct tgaaactgcg tgtgcgactg
      841 attgtttttg ataaagaaga caagggtccc aagaaaaagg tgttggacgt tcgagagcaa
      901 gaggtttatg tcggcgaatt gcccctgatg actgaacgcg gaacgtttct cattaacggg
      961 accgagcgag tggtggtcag tcagttgcac cgctcgcccg gtgcgtcctt tactcatgac
     1021 aaggggcgca cgcacgccag cggcaaagtg ttgtactctg ccagaattat tccgtatcgc
     1081 ggatcgtggc tcgattttga gttcgacgcg cgcgatatct tgtacgtccg catcgatcgc
     1141 cgacggaaaa tgccggcgac catcctcctg aaggcctttg ggtatagcac cgacgacttg
     1201 ctccggatgt actatccggt cgaagaaatc cgcgtttcca agggcaaatt gtttcgaaag
     1261 ctcgatcctg aaatccatca cgggctgaag tgctcgacag aggtgatgga gaagggcggc
     1321 aaggatccga ttgtccgcga aggagcgaag ctgacgaagg ttctgattgc caaattaaag
     1381 gcagcgggga tcaaggaaat tcccgtgact cctgccgagt tggtggggcg ggcggtcctg
     1441 acggatttgg tcgacggcgg gaaaaagcag gccctggcgg agaagaatca gcggctgacc
     1501 gaagagattt tggagaaaat tctggatagc gacatcgagg aattcaaggt catctatctg
     1561 gatacaacca atgcgaccct ggtcattttg gataccctcg atatggagcg aaccggctcg
     1621 aaggaggagg cgatggtcga gatctatcgc cgtctcaggc cgggagaaac tccgtcagtc
     1681 gaaacggcgc gcgcgctgtt cgataattta tttttgagtc ccaagcgtta cgatttgtct
     1741 cccgtaggcc gcctcaagct gaataaaaaa ctgggactcg atttcgctct ggagcaacgc
     1801 acgctgactg cgcaggatat cgtcgaagtc gtccgatacc tggtgaacct taagatcggc
     1861 cgaggggaaa tcgatgacat cgaccacttg gggaatcgtc gtgtgcgatc ggtcggcgag
     1921 ttgttggaga atcaattccg tctcggcctt gtgcgcatgg agcgcagcat taaagagcgc
     1981 atgaacctgt tggacatgga gaccgtgttg ccccatgacc tcatcaacgc aaagcccgtg
     2041 gtggcggcgg tgaaagagtt cttcagcagc agtcagctct ctcaattcat ggaccagacc
     2101 aatccgctgg ctgaaattac acacaagcgc cgcttgtcgg cgctggggcc tggcggattg
     2161 acccgcgagc gtgccggctt cgaagtgcgt gacgtccatc cgtcccacta cagtcgtatt
     2221 tgcccgattg aaacgccgga aggtccgaac atcggattga tcacttcttt ggcgacctat
     2281 gcgcgcatca acgagttcgg cttcatcgaa gcgccttacc gaaaggtcgt gaaggggcgt
     2341 gtcagcgacg agttggagta cctctcggcc atcgagggtg acaagtacat catcgcccag
     2401 gccaactcga aagtggatgg ctccaatcgg ctcgtgtctg aaaccgtttc ggcgcgctct
     2461 gccggtgatt ttattaccgc tactcccgac aagattgaat acatggacgt gtccccgaag
     2521 caggtcgtca gcgtcgcgac ggcattggtg ccgttccttg agcacgacga cgcgaaccgc
     2581 gcattgatgg gatcgaacat gcagcgccag gccgtgccgc tgctcaaggc tgagtctccg
     2641 ttagttggaa ccggcatgga agctgtggtc gcgcgcgatt ccggatacgt cgtgcaggct
     2701 aagcgtgaag gtgtcgtgga aagtgttgat gcgacgcgca ttgtggtgcg tgccgatgcc
     2761 aaggaaggtc gcaagcggaa cgattcagga cttgatgtgt atgaaatgat caagttccag
     2821 cggtcgaatc aaaatacgtg catcacccag acgcctgtgg tccgcatcgg tgagccggtc
     2881 aagcgagggc aagtactggc cgacggtccg gcgatcgatc acggtgaatt ggcgctgggt
     2941 aagaatgtcc tcgtcgcgtt catgccgtgg ggcggctata acttcgaaga cgcgattcta
     3001 ctcagtgaaa aactcgtgcg ggaagatgcg ttcacctcca tccatatcga agagttcgag
     3061 gtagaggcgc gcgacaccaa gctgggtaag gaagatatca cgcgcgacat tccaaatgtc
     3121 ggagaggaag cgcttcgcga tttggatgag agcggcatta tccgcatcgg cgccgaagta
     3181 aagcctggcg acattttggt cggcaaggtc acgccgaagg gcgaaaccca gttaacgccg
     3241 gaagagaaat tgctgcgggc gatcttcggc gaaaaggccg gcgacgtcaa ggatacctct
     3301 ctcacggttc ctcccggtgt ggagggaatc gtcgtcgatg tgaagatttt ctcccgcaag
     3361 ggcctggata aggacgagcg ctcgaagagc atcgagagcg aagatcacat gaagctgcag
     3421 cgcgaccatc aggaagagct gcgcatcatt gaggatgaaa agacgaagaa ggttcgcaag
     3481 ctcctgctcg gaaaagtggt cggtcgagat ctgatggacc ccgagacggg cgatgtcatc
     3541 ctgaagaaaa aagggaagct cactgcggag atcctgaagc gtttgccgga tgatatggtg
     3601 cgccacatca tcctcagcga tccggatgag cagaaggaat tggaagacgt cgagcgacgt
     3661 gccaaggagc agatcgagat tttgcagacc ttgtacgatg aaaaagtcgg tcggctgaga
     3721 cggggagacg agcttccgcc tggtgtgatc aagttggtga aggtctacat cgcgatgaag
     3781 cggaagatcc aagtcggcga caaaatggcg ggtcgccacg gcaacaaagg cgtcgtgtca
     3841 cgcgtattgc ctgaagagga tatgccctat ctgccggatg gtacgccggt agaaatcgtg
     3901 ttgaatccgc tgggcgtgcc gtctcgtatg aacgtgggtc aaatcctgga gacccatctt
     3961 ggttgggcgg ctcgggcatt gggaattaaa gtagccagcc cagtgttcga cggcgcgtca
     4021 gagaaggaga ttaaggagct tctcaagaaa gcgaagctgt cgccaagcgg tcaaaccgtg
     4081 ttgatggacg gccgaaccgg cgaatcgttc agcagtccgg tcacggtggg atatatgtat
     4141 gtgttgaagc ttcaccactt ggtggatgac aagatccacg cacgctccat cggtccctat
     4201 tcgttggtga ctcaacaacc gttgggtggt aaggcccaat tcggtggtca acgattggga
     4261 gagatggaag tgtgggcctt gcaggcctat ggggccgcct ccattctcca ggaattcctg
     4321 acggtgaaat cagacgatgt ccccggccgg tcgcgcatgt atgaggcgat tgtgaaggga
     4381 gagccgttcc tggaacctgg attgccggag tcgttcaacg tgctggtcaa agagctgcaa
     4441 agtcttgggc tcgacgtaga gctagttaaa tcaaaggact gattctagtg ctgagtcttg
     4501 agagcaacga tcggatagct caccactcag aactgcgctc aggcgaccgt taaggaggga
     4561 tcaaccttgg aaggtgtata cacattattc gagaagccgc gggattcggt gtcgttcgac
     4621 tcgatgcgca ttcgcattgc gtcgcccgaa aaaatccgct cgtggtcata tggcgaagtc
     4681 aagaagccgg aaacgatcaa ctatcggtcg ttcaagcctg aaaaggacgg cttgttctgc
     4741 gccaagattt tcggcccgat caaagattgg gaatgcaact gcggtaaata caaacgcatg
     4801 aagcatcgcg gcatcgtctg cgataaatgc ggtgtcgaag tcattcagtc aaaggtgcgc
     4861 cgcgaacgga tgggccacat tgagttggct gcgccggtcg cacatatctg gtttttgaaa
     4921 ggtgtgccga gccgcatcgg gacgctcctt gatatgagcc tcaagcagct cgaaaagatc
     4981 ctctacttcg agagctacgt gatggtcgat cctggatcga caagcatgag tgagcaagag
     5041 ctggtctcag aagagcagtt gcgttcattg cagtccgaat atggcagcgg tgcgttcaag
     5101 gttgggattg gcgccgaagc cattcgggaa ttgcttcgca aggtggacat caatacccag
     5161 tgggacgaat tgcatgtgaa ggcgaaggcc tccgcatccg ctgcgctcaa aaagaaatac
     5221 gccaagcgct tgaaggtctt ggaggcattt cgccgttccg gcaacaagcc tgaatggatg
     5281 atcatggatg tcatcccggt attgccgccg gaattacgcc cgctggttcc gttggatggt
     5341 ggccggtttg cgacgtcaga cctcaatgac ctgtaccggc gcgtcatcaa tcggaacaac
     5401 cgcttgaagc gcttgatcga actcaaggct cccggcgtaa ttattcgcaa tgaaatgcgc
     5461 atgctacagg aggcggtgga cgctctgttc gataacggcc gtcgcggccg tgccatccgt
     5521 gggccaaaca agcgcccatt gaagtcattg agtgacatgc tgaagggcaa gcagggacgt
     5581 ttccggcaga atttgctcgg aaagcgcgtc gactattccg gccgaacggt tattgtcgtc
     5641 ggtccggagc tgcggttgca tcaatgcggt ctgcccaaaa agatggcatt ggagctgttc
     5701 aagccgttta ttttccacaa gctggaagag cgtggcgcag ctacgaccat taagagtgca
     5761 aagcgtctgg tagagaaaga gcgtcctgaa gtgtgggatg tgctggatga agtcatccgt
     5821 gagcatccgg tgttgctcaa ccgcgctccg acgttgcaca gactcggaat tcaggccttt
     5881 gatccggtct tggtggaagg taaggccatc cggctgcatc cactcgtctg cgcggcgttt
     5941 aacgccgact tcgacggaga ccagatggcg gtccacgtgc cgttgtcggt tgaagcgcag
     6001 gttgaggccc gcgtgctcat gatgtcgatc aataatattc tgtcgccagc gaacgggaaa
     6061 ccgatcgcgg ttccgtcaca ggacatggtg cttggttgtt actggttgac caaggagcgt
     6121 gtgggtgcaa agggcgaagg caagttgttc ggatctcccg aagaagcgcg cattgcgtac
     6181 gatgcggggg cgttggatga gcatgctagg atcaaggtgc gatgcaacgg tacgctcgtg
     6241 cagactacag ccgggcgcgt cattctgtcg gaaattctcc ctccaatgat gccgtttgcc
     6301 gatgcgaata aattgatgac aaagaaggaa atgtcaaagc tgatcgacgc ggtctatcgg
     6361 caggctggcc accgcgaaac ggtcaccttc ttggataaga tcaaggacct gggtttccat
     6421 tatgcaacca gggccggcat gtcgatctgt atcgacaaca tgcacattcc ttcccggaag
     6481 gaagatctta ttggcaaggc tcagcatgaa gtcaatgaaa tcgaaaagca gtactccgaa
     6541 gggttgatta ccaacggcga acgctacaac aaagtcatcg acatttgggc gcatgtgacc
     6601 gagcaggtgg ccaatgagat gatgaaggag ttgggcgctg gcggtgatcc cgccaaggct
     6661 gaatccttca acccgatctt catgatggcg gattccggtg ctcgaggcag ctcgcagcaa
     6721 attcgtcagc ttggcggtat gcgcggactg atggcgaagc cgtccggtga aatcattgaa
     6781 actccgatca cggcgaactt ccgtgaaggg ttgacggtat tgcagtactt catttcgacg
     6841 cacggtgcgc gaaaaggttt ggctgacacg gcgttgaaaa ccgcgaactc cggttatctg
     6901 acccgtcgat tggtcgacat cgcgcaagat gtcatcgtga ccgaagaaga ctgcggcacg
     6961 accgacggaa ttctcgtaag cgcgctgctt gaaggtggcg agattattca gccgctcgaa
     7021 gagcgtctgt tgggtcgtct ggccggcgaa gacattcgag atccggtgac gggcgagatc
     7081 attgtctcgt tcaatgagga aatcgacgaa gagcaagcca aggcggtggt ggaagccggt
     7141 gtggatcgcg taaagatccg atcggtcttg acatgccagt cggcccgtgg cgtgtgccgt
     7201 ctctgttacg gccgtgactt gtcgcgagga cggctggtgg aaaagggcga gccggtcggc
     7261 gttattgctg cccaatccat cggcgagcct ggcactcagt tgacgatgcg tacgttccac
     7321 atcggtggta cggctagtaa ggttgttgag cagacagtct tggaagccaa gcatgccggt
     7381 cacctgaagt atatgagctt ggatgccaag aaaaatgccg atgtgcacaa cgccggcatt
     7441 gccgttcgga ataaagaggg tgaatgggtc gtcatgaatc gcaatgcgaa aatcgcgatt
     7501 gtcgacgaca gtggccgtga gcgtgaaaag tatccggtcg tgtatggcgc caagatcaag
     7561 ttgaaggacg gtgatcggat cgaagtcggc cagaagttgg tcgaatggga tccgtactca
     7621 ctgaccatcc tcacggagac cggcggaaag gtcgcgtatg gcgacattct cgaaggcgtc
     7681 accatgaagg aagagtttga cgaggtgact ggtttgtctc gaaaggtcat cattgagcaa
     7741 agcggggcca cgcttcggcc gcgcgtttcc atcaaagatg acagcggtaa gaccgccaaa
     7801 gtctccggag ctggagcacc ggtggctcga tatctgttgc cggtcggcgc gcacattttc
     7861 gttgaaaagg gcgccatggt gcatcccggc gatgtgttgg cgaagattcc gcgggaaacc
     7921 acaaagacca aggacatcac tggaggtctt ccgcgagtcg ccgaattgtt cgaggcgcgc
     7981 aagcccaaag agcaggccgt cattagtgaa atcgacggcg aagtttccta tggcgggttt
     8041 gtgaagggta tgcggaaggt gctggtcgat aacaaaatgg gggatgtgaa ggagtacttc
     8101 attcccaaag gtaagcacgt caacgtgcat gagggcgact gggtgcgagc tggtgagcct
     8161 ctcatggacg gatccgccaa tccgcacgat attttggatg tgttggggcc gaaggagctc
     8221 cagaaatatc ttgttgatga agtgcaggac gtgtatcggc ttcagggcgt gtccatcaat
     8281 gacaagcaca ttgaaatcat tgtgcgtcag atgttgcgaa aggttcgcat tgaggatcca
     8341 ggagacacgt ccttcttgcc tggtagtcag gtaagtaagg gcatgttcga cgtggaaaat
     8401 cagcgtgtct tggaaaaaga cggcaagcca gccctcggaa agccggtcct gctgggtatt
     8461 accaaggccg cgttgactac cgacagcttc atctcggcgg catctttcca ggaaacgacc
     8521 cgggtgttga cggaggcggc cataaacggc agggaggata atctccttgg cctgaaggaa
     8581 aacgtcatcg ttggacgatt gattccggcg ggcagcggtt tcgaggaata ccgagagacc
     8641 ttcgttgcga gcgctaaggc tccaggagag ttgtccggtg accagtctca accggtggcg
     8701 gttggacagg ctccgatcac ttctgtaggc agtgcgtcag aaaataatgc gtgaagaaca
     8761 agaaggttct tgacataagt agtacacatc tctataatcc gacggcttcg ctcaggagca
     8821 tttttgagca aatgcctgat tttcaagaaa gagtatagtg catgcctacg attaatcagt
     8881 tggtgcgaaa aggccggacg ctcgttaagt cgaagacgaa aagtcccgcg ttgaagcgtt
     8941 gcccgcagaa gcgtggcgtc tgtctccgtg tctacaccac aactccgaag aagcctaact
     9001 ccgcgcttcg taaggttgcg cgtgtgcgtt tgaccaatgg gatggaagtg acaacctaca
     9061 tccctggtgt gggtcataat cttcaggagc actcgatcgt cctggttcgt ggtggtcgtg
     9121 tgaaggactt gccgggcgtt cgttatcaca ttgtgcgtgg ttctttggat gcggtgggag
     9181 ttgctgatag aaagcaggcc cggtccaagt acggggcgaa gcggcccaag tagatagttc
     9241 atcctctcat tgcgcgtacg tgcaatgaat actgacttta ttttatagga caacgatgcc
     9301 acgcggacaa tttttcggtc atcgagaagc gcagcctgat tcgaagtatc gagacaagct
     9361 tgtcgggaag ttcttgaacg tcctgatggg tggtgggaag aagagcacgg cagagcggat
     9421 ctgttatgga gccttcgatc tgatccagga gaagacgaac ggcggcgatc cgatgaagat
     9481 cttcaaatcg gcgatcgata acgtgaagcc ggttgtggag gtgaagtctc gtcgggttgg
     9541 tggtgcctcc tatcaggttc cggttgagat tcggccgtct cgccgtgtct cgttggcttt
     9601 gcgatggatc accgaatatt cccgctcccg tggcggaaag agtatgcagg ataggcttgc
     9661 ggctgaattg ttggatgcat ccaataatac gggtgcatca gtgaagaagc gtgaggatgt
     9721 ccaccgtatg gcagaggcca ataaggcctt tgctcattat cgttggtagt gttgagttgt
     9781 gctgctgttg agccgggctg cgatatttgc tcgtaagtgt gagtgtcgca gtgaatggtc
     9841 tccggctctg atggcggcac gttcgttttt tctgggggag ttgtggctag gcagacaccg
     9901 ttagagcgta caaggaatat cggcatcatg gcccacattg atgccggaaa gacgacgacc
     9961 actgagcgca tcctctttta tacgggcatg acccataaga tgggtgaagt gcatgagggt
    10021 gctgcgacca tggactggat ggagcaggag cgcgagcgtg gtattacgat caccgcggcg
    10081 gctacaacct gtttttggcg tgatcatcgc atcaatatta ttgatacgcc gggccacgtc
    10141 gatttcacga ttgaggtgga gcggtctctg cgcgtgctcg atggtgcggt tgcggcgttc
    10201 gattctgttc agggtgtcga gccgcagtct gaaactgtct ggcgtcaggc tgataagtat
    10261 gaggtccccc gtatcgcctt catgaataag atggatcgga ttggtgcgga tttttatgcg
    10321 agtgtccagt ccatcatcga tcggctgggg gcgaatcccg ttcctattca gattccgatc
    10381 ggacgtgaag ccgagtttcg cggttcggtg gatctgattt cgatgaaggg ctatttttac
    10441 gacgacgaga cgcttggtgc gaaatataag atcggtgaaa ttcctgctga tatggtcgat
    10501 caggccaatg actatcggca gaaaatgctc gatgccgttg tcgaattcga cgatcaggtg
    10561 atggagaagt atcttaacgg ccagtccttg gctgaggatg aggttcgccg cgttgttcgt
    10621 gccggcacca ttgcgatgaa gattgttcct gttatttgtg gttcggcttt caagaataag
    10681 ggtgtgcagc aattattgga tgcagttgtg gatttccttc cgtccccggt tgatattcct
    10741 ccagttattg gtgtggatcc tgccaccggg aaagatgtgg agcgtagccc ttccgatacc
    10801 gagccatttt ccgctctcgc attcaaaatt atgacggacc cttttgctgg acagctgacc
    10861 ttcttccggg tctattccgg aacgttaaag accgggactc ctgttctcaa tgtcacgaag
    10921 gggacgaaag atcgggttgg tcgtctcttg aagatgcacg caaataagcg tgaagagatc
    10981 gagattgtgt atgccggcga tatcgctgct gcggttggtc tcaagagcgc gacgaccggt
    11041 gacacgctgg cggacgagaa gcaaccggtt ttgttggaaa tcatgaagtt tcctgagccg
    11101 gttattgcga tggctatcga gcctaagact aagcctgatc aggaaaaaat gggctttgca
    11161 ctgcaaaagt tagcccagga agatccatcc ttccgcgttc gcacggacga agagaccgcc
    11221 cagaccatta ttgctggaat gggtgagctg catctcgaaa ttattgtcga ccgtttgatg
    11281 cgcgaattta aggttgaggc gaatgtcgga aagcctgagg tggcattccg agaaacgatt
    11341 cgccggaagg ctgaggctga atcgaagtac atcaagcaga ccggtggtcg agggcagtat
    11401 ggccacgtgg tgatgactgt tgagccatcc gagcctggga agggattgga gttcgtcaat
    11461 aagacagttg gtggctctat cccgaaagaa tatattccgg cgatcgaaaa gggtgtgaag
    11521 gagcgaatgg aaaccggtgt tgttgccgga tttccgctgc gagatgtgaa ggtcaccgtg
    11581 attgatggtt cgtatcacga tgttgactcg aacgaaatgg catttaagat tgccgcctcg
    11641 atgggctttg ccgatgcttg caagaaggcg gatcctgtcc ttcttgagcc aatcatgaag
    11701 gtggaggtgt tggtgcctca ggactttatg ggcgatgtca tcggaaacct gaatggccgc
    11761 cgcggaaaag ttcagggcat gaaggttcgg gccggggctc aagcgatcga agcgaccgtg
    11821 cctcttatgg aaatgttcgg atatgcgacg gatttgcgtt cccgtacgca gggccgtgca
    11881 acatacagta tggagtttga ccgctacgat caggtgcctc ggcagatcgc ggaagcgatt
    11941 actgctaagc atcgtggaga gtagggtctg ggttgtgtga actagggagg atcggggatg
    12001 gcgaaggcga aatttgagcg acgaaagccc cacgtgaaca tcgggacgat cg
//
LOCUS       DAOQPD010000101        11860 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_2768_length_11860_cov_21.804320, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000101 DAOQPD010000000
VERSION     DAOQPD010000101.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 11860)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 11860)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11860
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2768_length_11860_cov_21.804320"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1784)
                     /locus_tag="PK063_16815"
     CDS             complement(<1..1784)
                     /locus_tag="PK063_16815"
                     /inference="COORDINATES: protein motif:HMM:NF015655.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98765.1"
                     /translation="MARRSSQNDSLADPAGTGASPVFPDPTPLLVASGLDADEVVRIL
                     GPYGLRNPTEADTNIQSMAGEPHTRRLLAGILSRLLAEVARTADPDQALNHWERLFAG
                     SANRSSLLQYLQASPRMLGLLCTIFGNSDSLAFALIRDPMLVYWLAEEDVLTTAPTRE
                     GMVAALRQSLGSLKATELKLDVLRRVRRREMLRIGVRDLLRLATVEETVGSLSDLASV
                     LIHAAYEIVDKDLKTQHGTPMHQRPDGTWIETEFVVIGMGKLGAHELNYSSDVDLIYV
                     YASADGETRKAKGNRQASIKPLSNEEYFEMLARSLTKALAEQTREGAVFRVDLRLRAE
                     GTVGQLARSVDAYAKYYAQRGQVWERLALLKAWPVAGSPAVGQAFVQMAEGFVFQSDL
                     QPLTRERALAVIRDVRSVKEMIDEKIAVRGHQHRNVKLGTGGIREIEFLVQTIQVLIG
                     GAVPDILDRKTVGALHRFCRHRFVNEDDQQQLTEAYWFLRDVEHKLQMMHDLQTHALP
                     DSHEELQRCAIRMGYYGESRKRAMEQFLADRQRHTAVVHQTFRSLFYHPETSDLLSAV
                     VAAAEGHSRRNPSRLEKETGPAGPPPDRS"
     gene            1855..4131
                     /locus_tag="PK063_16820"
     CDS             1855..4131
                     /locus_tag="PK063_16820"
                     /inference="COORDINATES: protein motif:HMM:NF015655.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98766.1"
                     /translation="MLHANTDRDQILATLAPLCPGIETDILQDFTSRMDADYFAAFSP
                     KLLAEHLSLAALLTPDHPCEVRFAKLDRKRLTITIVAYDYFSEFATICGLLSAFGLNI
                     EEGRIFTSAESEPARGGRQNSPYGTRPRPQGRPGLTRKKIVDVFTVTPTEGEPFTADD
                     QKRLAEQLSRMIILLDTNEFDEARQQVNRQLIEYLGTRRSSFSGLLHTVHITFDNSQS
                     ATDTIMDIRSDDTPAFLYAFANALAMRNVYISKAQFAIEEGKLHDRFYVRNRFGQKLL
                     DPGDQEQLRLTAVLIKQFTHALTWAPDPAKALESFDQFLDLVLEGSRQAGKKQAWDFI
                     NDKKTFPLLARLLGASDFLWEDFLRRQHVNLLPLLKDYRDAPLIKPQATLRKELNRLI
                     AKAKTDEARKEALNRFKDQELFRIDMKHIVEPGTNLPDFSLAISELAEVIVERSLLDC
                     QAKLTKRYGSPRLANKKPCPFAILGAGKFGGRELGYASDIEVLFVYGGPGHTTGKDGI
                     ENSEYFERLAQELLQWIEAKQEGIFHIDVRLRPHGGKGSLSNAFDEVCKYYSADGLAA
                     PFERQALIKLRHIAGDAALGRKVEAHRDSFVYSGAPWDLTTAIDLRRQQVKQLVEPGQ
                     VNLKHSHGGIVTLEYAIQYLQVMHGHRHASLRTPNTLRALAALIDADLIPRTTGENLR
                     KSYLFIRMLIDGLRMVRGNTKDLVLPPPDSDEFIFLARRVGYQTEDWQAGAKHLLSDI
                     EQHMKQNREFFEKMFGKV"
     gene            4333..4761
                     /locus_tag="PK063_16825"
     CDS             4333..4761
                     /locus_tag="PK063_16825"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98767.1"
                     /translation="MLTRVLAGLLLSVVLASCGQGDGGAGSGIKPVGEWAKIGETDTY
                     IYYADYASIKKADETVVMLDLFDYKSAQSEGGGAPALSKATEREYDCQNKKSQPLKSS
                     WYSEGMGAGTVVRSTGTSNQWSSAAQGTATGGLLKAACGN"
     gene            complement(4834..6003)
                     /locus_tag="PK063_16830"
     CDS             complement(4834..6003)
                     /locus_tag="PK063_16830"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009341 - beta-galactosidase complex
                     [Evidence IEA];
                     GO_function: GO:0004565 - beta-galactosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HMZ98768.1"
                     /translation="MHELANGRSVRKWPLSIPAGKTSLPLMFILSFLVLAGLPWAWGA
                     VDAAEVPTTPGIVKWHPGHYYAPMTFMRANANVMTQIYAELKATPALRGLQVRFAWPE
                     LEPEEGRYDFKGIEKVLAELAPLNKQLVILLELKSFNPQILPMPTYMRTEAYEGGAFP
                     FSSYGQSIPRGYNLKLWNSGVHDRLVALLTELGKRFNGHANFEGIGLPETALGQPIEL
                     LSSHDTEKFYDNLLDVQRQMRAAFPNTVTYQFVNYPREILPGFIEHMRTIGTGLGGPD
                     SFLDDPGLNFDHPNKPKGIYSYYPQMSGLIPLTPSVMQANYDNTRHDGKGRVPTVAEL
                     LAFGRDRLRANYLFWTRAPGHFQQVLEQMQRIPLQGNPSGGLDAVCPKAYVSCVE"
     gene            complement(6321..7097)
                     /locus_tag="PK063_16835"
     CDS             complement(6321..7097)
                     /locus_tag="PK063_16835"
                     /inference="COORDINATES: protein motif:HMM:NF012780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HMZ98769.1"
                     /translation="MAKRTKSSQEPADLLSRHIEEIRETLAAFQPFLSRRKATASLEG
                     FDEQAEEVLSETFGGASDELEAYYYAKLGEAAILPEEAQEAGTHNLERESLHQRKQVL
                     ESCLAQLELKKSTRVGRDWRRTLGERIDGRTVAEFMSSEVRSVHKGASIKEAGRLLQK
                     WRIGSLLVDDGSRYLGIITDTDLSRKAVAKGLDPNSTTVMSCMSKAVVTIEDSEPIKE
                     ALRLMKKEGIRHLPVTEDGTIIGVLSVGDLLRAYQKMLEL"
     gene            complement(7160..8764)
                     /locus_tag="PK063_16840"
     CDS             complement(7160..8764)
                     /locus_tag="PK063_16840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin--nitrite reductase"
                     /protein_id="HMZ98770.1"
                     /translation="MNKIEAIKTERDGLAVRDMLEHYAHAGWESIPEDDIQRLKWYGL
                     FLRNPTPGFFMLRVRMPGGQTTSVQLQALADIALAYGNGVIDVTTRQQVQLRHLTIAH
                     VPAVFAKLDEVGLTSMQTGMDSVRNVMTCPVAGLNPNELLDGTEIVRAINHEVLGNPA
                     YTNLPRKCNIAVTGCTDNCLHTETQDIALVPAYHDLGHDKCFGYNVLVGGKLGSGGYR
                     IASSLDMFVNPAEAFDVCRTLLHIYRDHGPRENRTQARLAFLVEAWGESRLRHEVEVR
                     MGRALPSAGVDARAAGERDHIGIFRQKQRGMNYIGLKILVGRIKAGDLRNIAALAERY
                     GTGEVRLSPAQAIVIPHISDRVVGELAEEPLVKQFAYNPSPLYKGLVSCVGSDYCNMA
                     VIETKRRAVETAHILERKLEGLKPITLHWSGCPAGCGNHLVADIGLLGKKARVGGKVV
                     DAVDIFVGGRSGPDPKLATKIMEDVPCDKLPAVLENLMPYHTRDKMHRVRGKAVAKST
                     ASAKSASSANAADGAISGLRPQPFPA"
     gene            complement(8761..8958)
                     /locus_tag="PK063_16845"
     CDS             complement(8761..8958)
                     /locus_tag="PK063_16845"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98771.1"
                     /translation="MKTNEETVVLTLLRRQAPQSFEQLMALSGLSASQVLLVVDRLSR
                     EGTVVLRKSGLDYSVALGSTI"
     gene            complement(9008..9448)
                     /gene="cynS"
                     /locus_tag="PK063_16850"
     CDS             complement(9008..9448)
                     /gene="cynS"
                     /locus_tag="PK063_16850"
                     /EC_number="4.2.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008824 - cyanate hydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009636 - response to toxic substance
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyanase"
                     /protein_id="HMZ98772.1"
                     /translation="MEKEAMRKAIKAQRLKKKVTIAQVAKKVGKNPTFVAAALNGNHR
                     LVPADAAKVGALLGLNQEQVAALSAFPIRADFPNLTDPFKYRLMEVIGVYGDSLREMA
                     NEMFGDGIMSAIDFTLDMEKVTGSQGEARCKITLNGKWLEYKTF"
     gene            complement(9502..10332)
                     /locus_tag="PK063_16855"
     CDS             complement(9502..10332)
                     /locus_tag="PK063_16855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HMZ98773.1"
                     /translation="MHTADHERIAGVAAKKWMFLEQAPGGYFILSSLAGIYLGFGIAL
                     IFSLGGPLAAAGSPVVKLVMGVSFGIALTLVIFAGSELFTGNNLIGAIGGLSRSLSWT
                     QVIQLNAWSWFGNLAGSMGLAWLIVESGVFAKGPSADLIEKVAAVKMSLPAWELFVRG
                     ILCNWLICLAVWMTGRTTNDTAKILLIFWCLFAFIGTGFEHSIANQSLLGMALFLPHD
                     VTVTWAAFWYNQLFVVLGNLVGGGLFVGGLYWMVSPYRVAEVPVTPVSSPATSAVVGS
                     "
     gene            complement(10650..>11860)
                     /gene="glnA"
                     /locus_tag="PK063_16860"
     CDS             complement(10650..>11860)
                     /gene="glnA"
                     /locus_tag="PK063_16860"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HMZ98774.1"
                     /translation="LVPDPATACMDPFCSVPTLSLIGNVVDPITREMYDRDPRFIAQK
                     AEKYLQSTKIGDTSYWGPEAEFFIFDHARYDQTNHSAYYHIDSDEGVWNMGQDGVNLG
                     GKIRHKEGYFPVPPTDTQQDIRTEMILEMEKAGIATEKHHHEVATAGQAEIDIRFDSL
                     LRTADKMMMFKYIVKNVARRHGKTVTFMPKPIFGDNGSGMHTHQSIWKDGKPLFAGKE
                     YAGVSQMCLNYIGGILKHAPALAAFTNPSTNSYKRLTPGFEAPVLLAYSSRNRSAGIR
                     IPMYSPSPKAKRIEVRFPDPAANPYLAFAAMLMAGLDGIENKINPGEPAEKDLYDLEA
                     KEAAKIRTMPGSLDEALNHLEKDHQFLLKGGVFSEDLIEAWIGYKRTKEVDTMRLRPH
                     PYEFFLYYDV"
BASE COUNT         2527 a         3698 c         3178 g         2457 t
ORIGIN      
        1 gaccggtccg gcggtggccc cgccgggccg gtctcttttt cgagccgaga cgggttgcgg
       61 cgggagtggc cttccgccgc agccaccacc gcggacaaga gatcagacgt ttccgggtgg
      121 tagaagagcg atctgaacgt ctgatgcacc accgccgtat gccgctgccg atccgcgagg
      181 aactgttcca tcgccctctt gcgcgactcc ccgtagtagc ccattcgaat cgcacaacgc
      241 tgcagctctt catggctgtc aggcaacgca tgcgtctgca gatcgtgcat catctgcaac
      301 ttgtgttcga catcccgtaa aaaccaatag gcctcagtca gctgctgctg atcgtcttcg
      361 ttcacgaagc gatgccggca gaaacgatgc agagctccca cggtcttacg atccaggata
      421 tcgggcactg ctccaccaat cagcacctga atcgtctgta ccaggaattc gatctcccga
      481 atgcctccgg tccccagctt cacattgcga tgctgatgcc cgcgcaccgc gatcttctcg
      541 tcaatcattt ccttcactga acggacgtcg cgaatcaccg ccaaggcccg ttctcgcgta
      601 aggggctgga gatcagattg aaacacgaac ccttccgcca tctgcacaaa cgcctgcccg
      661 accgcaggcg aaccggcgac aggccaagcc tttagcagtg ccagtctttc ccagacctgg
      721 ccgcgctgcg catagtactt cgcataggcg tccaccgacc gcgccagttg ccccacggtt
      781 ccttcggcgc gaagccggag atccacgcga aacactgccc cttcacgagt ctgttccgcc
      841 agggctttcg tcagcgaccg cgccagcatt tcaaaatact cttcattgga cagaggtttg
      901 atgctcgcct ggcgattgcc ttttgccttg cgcgtttcac cgtctgcgga tgcatagaca
      961 taaatcaagt cgacatccga gctgtaattc aactcatgcg cgccaagctt acccatcccg
     1021 atcacgacaa attcggtttc tatccaggtg ccgtctggcc gttgatgcat cggggttccg
     1081 tgctgggttt tgagatcctt gtcgacgatc tcgtaggccg catggatcaa tactgacgcc
     1141 agatcagaca gcgatccgac cgtctcctcc acagtggcca ggcgcagaag atcgcgtacg
     1201 ccgatccgta gcatttcccg tcgccgcacg cgacgcagca cgtcgagctt caattcggtg
     1261 gccttgagag agccgagact ctggcgcaac gcggccacca tcccctcccg ggtcggagcc
     1321 gtcgtcaata catcttcttc cgccagccaa tagaccagca tcggatcgcg gatgagtgca
     1381 aacgccagag aatcactgtt tccgaagatg gtacacagca gccccaacat tctgggcgag
     1441 gcttgcagat attgcaggag agaagaacgg tttgcgcttc cagcaaaaag acgttcccaa
     1501 tgattcagcg cttggtcggg atcggcagta cgagccacct cagccagaag acgggagaga
     1561 atcccagcca acaggcggcg ggtatgcggc tcgcccgcca tgctttgaat attcgtatcc
     1621 gcctcggtgg gattccgtag tccatacggc cccaggatcc gcaccacctc gtccgcgtca
     1681 agaccggatg cgaccagcaa gggggtcgga tcggggaaca ccggcgaggc gcccgttcct
     1741 gcagggtcag cgagcgaatc attctgggag gaacgtcgtg ccatggcgcc gcattatact
     1801 ggcgcaattc ttccggtaca acgacagcac cttcgggtat actccacgga caccatgctg
     1861 cacgcgaaca ccgatcgcga ccagatcctc gccaccctgg cgccgctctg cccgggcatc
     1921 gagaccgaca tcctgcaaga ctttaccagc aggatggacg cggattactt cgcagcattc
     1981 tctcccaaac tgctcgccga gcatctctcg ttggccgcat tgctgacgcc ggaccatccc
     2041 tgcgaagtgc gattcgcaaa actcgatcgc aaacggttga ccatcaccat cgttgcgtac
     2101 gactactttt cggagttcgc caccatctgc ggcctcctct cggccttcgg tttgaatatc
     2161 gaggaaggcc gcatctttac ttctgccgaa agcgaaccgg cgcgaggcgg ccgccagaac
     2221 agtccctacg gcacacgtcc cagaccgcaa ggcaggccgg gactgacgag aaaaaagatt
     2281 gtggacgtct tcacggtcac gcctacggag ggagagccct ttactgctga cgatcaaaag
     2341 cgcttggccg aacaattgtc ccgcatgatc attctgctgg acaccaacga attcgatgaa
     2401 gcacgccagc aggtcaacag gcagctgatc gaatacttgg gcacacggcg tagttcattc
     2461 agcggcctgc tccataccgt tcacattacc ttcgacaaca gccagtcggc caccgacacg
     2521 atcatggaca tccggtccga cgacacgccg gcgtttctct atgccttcgc caatgcgctg
     2581 gctatgcgta acgtctacat cagcaaggcc cagttcgcga tcgaagaggg aaagttgcac
     2641 gaccgctttt atgttcgaaa tcgcttcggg caaaagttgc ttgatccggg tgatcaagag
     2701 caactccggc tcactgcggt gctcatcaaa caattcacac acgcgctcac gtgggcaccc
     2761 gatcccgcta aagcgctgga atcgtttgat cagttcctcg accttgtgct tgaggggtcc
     2821 cgccaagccg gaaaaaaaca ggcgtgggac tttatcaatg ataaaaagac gtttccactg
     2881 ctcgcgcggc ttctcggcgc cagtgacttt ttatgggaag actttcttcg gcggcaacat
     2941 gtcaacctgc tgccgctgct caaggactat cgcgacgcgc cgctcatcaa gcctcaagcc
     3001 acgctgcgga aagagctgaa ccgcctcatt gccaaagcca agaccgacga agcacgcaaa
     3061 gaagcgctca accgcttcaa ggatcaggaa ttgttccgta tcgacatgaa acacatcgtc
     3121 gagccgggaa ccaaccttcc tgacttctct ttggccattt ccgaactcgc cgaagtcatc
     3181 gtcgagcgca gcttgctcga ctgccaagca aagctcacta aacgctatgg atcgcctcga
     3241 ctcgccaata agaaaccctg cccgtttgcc atcctgggtg caggaaaatt cggcggccgc
     3301 gaactcggat atgcctccga catcgaggtg ttgttcgtct atggcgggcc tggtcacacg
     3361 accgggaaag acggcatcga aaacagcgag tatttcgagc ggctggcaca ggaactgttg
     3421 caatggatag aagccaagca agaaggcatc ttccatatcg atgtccgcct ccgaccacac
     3481 ggaggcaagg ggtctctctc caatgcgttt gatgaggtct gtaaatacta tagcgccgac
     3541 ggcttagcgg cgccgttcga gcggcaggcg ctcatcaagc tgcgtcatat cgcaggagac
     3601 gccgcgctcg gcaggaaggt ggaagcccat cgcgacagtt ttgtgtatag cggcgctccc
     3661 tgggatctga cgactgcgat cgatctgcgt cgccaacaag tcaaacaact cgtcgagccg
     3721 ggccaggtca atctcaaaca cagccacgga ggcattgtca cgctggaata tgcgatccaa
     3781 tacctccagg tcatgcatgg tcatcgccat gcgagccttc gtacgcctaa cacgctgcga
     3841 gcgttggccg ccttgatcga cgcggacctg attccacgta caaccggtga gaatttgcgt
     3901 aaatcctacc tcttcatccg catgctgatc gacggcctgc gcatggtgcg cggcaacacc
     3961 aaggatctcg ttctgccgcc tccggactcc gacgaattca tcttcctcgc ccgccgcgtc
     4021 ggatatcaga cagaagactg gcaagccggg gcgaaacacc tgctgtcgga catcgaacag
     4081 cacatgaaac agaatcgaga gttcttcgag aagatgttcg gaaaggtgtg aggccacgca
     4141 ggccactgaa gtcattgccg gctccatcgt cttcgtaaca ttgagccccg ccctatctgc
     4201 tggaagggcc gttccacaag cacctctcgt cctctgcttc tcgttaccta cgtagcgcat
     4261 gacccccgcg tcgagttttg gccaaaccat ggtacagtgg aacggcggag tcacttcggg
     4321 aggaggatta ccatgttgac gcgagtattg gcagggctgt tattgagcgt ggtgctggct
     4381 tcatgcgggc aaggcgacgg cggagccggc tccggcatca agccggttgg agaatgggcc
     4441 aagatcggcg agacggatac ctacatctat tacgccgatt acgccagcat caaaaaagca
     4501 gatgaaacag tcgtcatgct ggacctgttc gactacaaaa gcgcacagag cgaaggggga
     4561 ggagccccag ccctgtcaaa ggccaccgag cgcgaatacg actgtcaaaa taagaagagc
     4621 cagccgctca agtccagctg gtattccgaa gggatgggag ccggaaccgt cgtgcgctcc
     4681 accggcacct cgaatcaatg gtcctctgct gctcaaggga ctgcaaccgg agggctgttg
     4741 aaggccgcct gcggaaatta gccgacggcc gaaacacgcc gcctcgcgct acgttactcg
     4801 agccggcagg caatacctgc catccggctg ccgctattct acgcaggaga cgtacgcctt
     4861 gggacagacc gcatcaagcc ccccggacgg attcccctgc aagggaatac gctgcatctg
     4921 ttccagcacc tgctggaaat gccccggtgc gcgcgtccag aacaggtagt tggcccgcaa
     4981 tcgatcccgg ccgaacgcca gcagttcggc aacggttggt actcgcccct ttccgtcatg
     5041 cctggtgtta tcgtagttcg cctgcatgac cgagggcgtc aggggaatca ggccagacat
     5101 ctgcgggtaa taggaataga tccccttggg cttgttcgga tgatcgaagt tcaatcccgg
     5161 atcatctaga aaactatccg ggccgcccaa cccggtaccg atcgtgcgca tgtgctcgat
     5221 gaagccgggc aatatctcac gcggatagtt cacaaactgg taggtcacgg tattgggaaa
     5281 agcggcacgc atctgccgct gcacatccag caggttgtcg taaaactttt cggtgtcgtg
     5341 gctggacaga agctcgatcg gctgccccaa ggcagtctcc gggagaccga tgccttcgaa
     5401 gttcgcatgg ccgttgaaac gcttgcccag ttcggtcagc agcgccacca gtcgatcgtg
     5461 cacacccgag ttccagagtt tgaggttgta cccgcgagga atgctctgcc catagctgct
     5521 gaagggaaag gcgccccctt cgtaggcttc cgttcgcata taggtcggca tcggcaggat
     5581 ttgcggattg aaagacttca gttcgagaag aatgaccaac tgtttgttca agggcgccaa
     5641 ttcggccagg accttttcga tccctttgaa gtcgtagcgg ccttcttccg gttctagttc
     5701 cggccaggca aaccgcactt ggagaccgcg tagcgcaggc gtcgccttca gctcggcgta
     5761 gatctgcgtc atgacattcg cattcgcccg cataaaggtc atcggcgcat aataatgccc
     5821 cggatgccac ttcacgatgc cgggggtggt tggcacctcg gcggcatcca ctgcgcccca
     5881 cgcccatggc aggcccgcga gaacgaggaa gctcaggata aacatcagag ggagagatgt
     5941 ttttccggca gggatagaga ggggccattt acgtactgac cgtccattcg ctagctcgtg
     6001 catacgtctc ctttccgata ggtctactgc cagtgaaaga ccgccgcgcc tctcactgca
     6061 ggcgcatgat agcacgagag gctcccaccg tactgtcctg tggggttcag tacttatgta
     6121 gtggaggcaa tgaggaaaat cggccccctc tcctccattg tcgagcgagc cggcactcga
     6181 catgaattag gtggttcgtg agtcagagaa aggtgacatc tcaggaaggg cgccaaacgg
     6241 cggtcatggc gaaactgttc gagcacggcg caaaccggca gcgctcgtgc gccgccggtt
     6301 tggcatagaa aaccttctcc ttacaactcc agcatttttt gataggcccg aagaaggtcg
     6361 ccaacagaca acaccccgat gatggtgccg tcttctgtca ccggcagatg ccggatgcct
     6421 tcttttttca tcagtcgcaa cgcttctttg atcggttcac tatcttcaat ggtcaccaca
     6481 gccttgctca tgcatgacat gacggtggtg ctgttcggat ccaacccctt ggcgacggcc
     6541 ttccggctca gatccgtgtc cgtgatgatg ccgagatagc gtgatccgtc atcaacgagc
     6601 agtgacccga tacgccactt ctgcagcaac cggcctgcct ccttgatcga agcgcctttg
     6661 tgcacgctcc tgacctcaga cgacatgaac tcggccacgg tgcggccatc gatccgctca
     6721 ccgagcgtcc gtctccaatc tcggccgacc ctggtgcttt ttttgagctc aagctgcgcg
     6781 aggcagctct cgaggacctg cttacgttga tgcaggctct cacgctcgag attatgcgtc
     6841 ccggcctctt gcgcttcctc cggaagaatt gccgcttcac cgagcttggc atagtaatac
     6901 gcttcgagct catcggacgc gccgccgaag gtttcactga gcacctcttc ggcctgctcg
     6961 tcaaaacctt ctagtgatgc cgtggccttc cgtcgcgata aaaatggctg gaacgcggcc
     7021 aacgtctcac gtatttcttc tatatgccgg ctgagcagat cagccggttc ctgcgatgat
     7081 ttcgttctct tggccatgct acctccttcg tgaaggcaag agaataaccc aactcccata
     7141 tcggctcaag tctcacgggc taggccggaa acggttgcgg cctcaggccg gagatcgccc
     7201 catccgcagc attggccgaa gaggctgact tcgccgaggc agtcgatttt gccacggcct
     7261 tgccccgcac acggtgcatc ttatcgcgtg tatgatatgg catcaggttt tcgaggaccg
     7321 ccgggagttt gtcgcacggc acatcttcca tgatcttcgt cgccagcttc gggtccggac
     7381 ctgaacgccc gccgacaaag atatcgacgg cgtccaccac cttgccgccc actcgggctt
     7441 ttttgccaag cagtccgata tccgcgacca ggtgattgcc acacccggca gggcagccgg
     7501 accaatgcag cgtgatcggc ttcagccctt ccagcttgcg ctccaggatg tgcgcggttt
     7561 ccacggcccg ccgcttggtt tcgatgacgg ccatattgca gtagtcgctc cccacacagc
     7621 tgaccagccc cttgtacagg ggagacgggt tataggcgaa ttgctttacc agcggctcct
     7681 ccgccaattc acccaccaca cggtcgctga tgtgcgggat cacgatagct tgcgcaggcg
     7741 acagccgcac ctcacccgtt ccataccgct ctgccagcgc tgcgatgttg cgcaaatcac
     7801 ccgctttgat ccggcccacc aatatcttga gaccgatata gttcatgccg cgttgttttt
     7861 gacggaaaat gccgatgtgg tcgcgctcac ccgccgccct ggcatcgacc cctgcagacg
     7921 gcaacgcgcg ccccatgcgc acttccacct cgtgccgaag ccgggactcg ccccaggctt
     7981 cgaccagaaa cgcgaggcgc gcttgggtgc gattttcacg cgggccatga tcacggtaga
     8041 tgtgcagcaa cgtccggcag acatcgaatg cttcggccgg attcacgaac atatccaacg
     8101 aactcgcgat gcgatatccg ccggatccca atttgccccc gaccaacacg ttgtagccga
     8161 aacatttgtc gtgccctaaa tcatgatacg caggcaccag cgcaatatct tgcgtctccg
     8221 tatgcagaca attgtccgtg cagccggtga cggcgatgtt gcacttgcgc ggcaaattcg
     8281 tataggccgg attgcccaac acttcgtggt tgatagcgcg gacgatctcc gtcccatcca
     8341 gtaattcatt cggattcaat cccgccaccg gacaggtcat cacgttgcgc acactgtcca
     8401 tgccggtttg catcgacgta agcccgacct catccagctt cgcgaacacc gccggcacat
     8461 gcgcgatcgt caggtgacgg agttgcactt gttgccgcgt ggtcacatcg atcacgccat
     8521 tgccatacgc caacgcgatg tcggccagcg cttgaagttg aaccgatgtg gtttgccctc
     8581 ccggcatccg tactcgcaac atgaagaagc ccggcgtggg attccgcaga aacagcccgt
     8641 accatttcag ccgttgaata tcgtcttcgg gaatggactc ccaccccgcg tgcgcatagt
     8701 gctcaagcat gtcgcgtacc gctaatccgt cacgctcggt tttgatggct tctatcttgt
     8761 tcatatcgtg ctccccagtg cgacggaata gtccaatccc gattttctca acacgacagt
     8821 accctctcga ctcaatcgat ccacgacgag caagacctgc gaggcactca gaccggagag
     8881 ggccatcaat tgctcgaatg attggggagc ctgccgccgg agaagcgtca gcactacggt
     8941 ttcttcattc gtcttcatga tgtcctcctt cgtctgagtg ccgcgtcacg gcatgttggt
     9001 cactgactta gaacgtctta tactcgagcc acttgccgtt cagcgtaatc ttgcaccggg
     9061 cttctccctg gctgccggtg actttttcca tatccagcgt aaaatcgatc gcactcatga
     9121 tgccgtcgcc gaacatttca ttggccatct cacgcagcga atcgccgtag acaccgatga
     9181 cctccatcag gcgatatttg aacggatccg tcaggttcgg gaaatccgcg cgtatcggaa
     9241 aggcgctcaa ggccgcgacc tgttcctgat tcagacccaa cagcgccccg accttcgcgg
     9301 cgtcggccgg aaccaggcga tgattgccgt tcagggctgc cgccacaaag gtcggatttt
     9361 tgccgacctt tttcgccact tgggcaatgg tcactttctt ttttaatcgt tgcgccttga
     9421 tcgccttccg cattgcttcc ttctccatca tctcctcctg tgattgatcc gcctgcaatg
     9481 atgcatactc gccgctctaa cttacgaccc gaccaccgcc gatgtggcgg gactcgatac
     9541 cggagtcacc gggacttcgg ccacccggta gggactcacc atccagtaca acccgccgac
     9601 aaacaatcca ccacccacga ggttccccag cacgacaaag agttggttgt accaaaaggc
     9661 cgcccacgtc acggtgacgt catgcggtag gaacagcgcc atacccaaca aggattgatt
     9721 cgcgatgcta tgctcgaacc ccgtgccgat aaaggcaaac aggcaccaga agatgagcag
     9781 gatcttggcg gtgtcattcg tcgtccgccc ggtcatccat acggccaggc agatcagcca
     9841 attgcaaaga atcccccgca cgaacaactc ccacgcggga agagacattt tcaccgccgc
     9901 cactttttca atcaggtccg ccgacggccc cttcgcgaac acgccggatt cgacaatcaa
     9961 ccaggccaac cccatcgatc cggccaaatt tccgaaccag gaccaggcat tgagctgaat
    10021 gacttgcgtc caggataggc tgcgtgacag accgccgatg gccccgatca agttgttgcc
    10081 ggtaaacagc tcggatcccg caaaaatcac aagcgtcaat gcgataccga atgacacacc
    10141 catgactagt ttcaccaccg gtgatccggc ggccgccaac ggccctccga gactgaaaat
    10201 caacgcaatg ccgaacccga gataaatccc ggccaaggac gacaggatga aatacccgcc
    10261 cggcgcttgt tccaaaaaca tccacttctt tgccgccacc cccgcgatcc gctcatgatc
    10321 cgctgtgtgc atgaggctct cccttcgatg gtccatcagt ctgaacagct caaaaaaaaa
    10381 gacgccctca tcccctgtgg gggagaagga cgtctttgtc ctgttcaacg agggtgcgat
    10441 tccctcgtca gttatgctgc gccgacttca acgtcggcag aaacgaaaaa ggcgtccgcc
    10501 actcttgaaa gaatgacgga cgccattgtc cgtgtaccgt atgtggtgca ggttcgaaat
    10561 caggcgtcgt tgcctgctct cacccacgca ctgcatgtat accatcgcct cccggtttcg
    10621 tcaagtgctc tcgacgagga ggccgccggc tacacgtcgt aatacagaaa gaactcgtac
    10681 ggatgcggcc gtaaccgcat ggtatcgact tccttggtcc gcttgtaccc gatccaggcc
    10741 tcgatgaggt cctcgctgaa cacgcccccc ttgaggagga attgatggtc cttctcgagg
    10801 tggttcagcg cctcgtccag gctgcccggc atggtgcgaa ttttcgccgc ttccttggcc
    10861 tcgagatcgt acagatcctt ttccgccggc tctcccggat tgatcttgtt ctcgatacca
    10921 tccagaccgg ccatcagcat ggccgcaaag gccagatagg ggttggccgc ggggtccgga
    10981 aagcgcactt caatccgctt cgccttgggg ctcggggaat acatcggaat acgaataccg
    11041 gccgaacgat tgcggctcga atacgccaac aagaccggcg cttcaaagcc cggggtcaac
    11101 cgcttgtacg agttggtcga cgggttggtg aaggccgcca gtgccggcgc atgcttcaga
    11161 ataccgccga tgtagttcag acacatctgc gacacgccgg catattcctt cccggcaaag
    11221 agaggcttgc cgtccttcca gatgctctgg tgcgtatgca tgcccgaccc gttgtcgccg
    11281 aaaatcggct tgggcatgaa ggtcaccgtc ttcccatggc gacgcgcgac gttcttgacg
    11341 atgtacttga acatcatcat tttgtctgcc gtccgcaaca ggctatcgaa gcgaatatcg
    11401 atttccgcct ggcccgccgt cgccacttcg tggtgatgct tctccgtcgc gataccggcc
    11461 ttctccatct ccaaaatcat ttccgtgcgg atgtcctgct gggtatccgt cggcggaaca
    11521 gggaaatacc cttccttgtg acggatctta ccgcccaggt tgaccccgtc ctggcccatg
    11581 ttccatacgc cttcatcgga atcgatgtgg tagtaggcgc tgtggttcgt ctggtcgtag
    11641 cgggcatggt cgaaaataaa gaactcggct tccggccccc agtaggaggt gtcgccgatc
    11701 ttggtgctct ggagatattt ttccgccttc tgggcgatga accgaggatc gcggtcatac
    11761 atttcgcgcg tgatcggatc gaccacattc ccgatgaggc tcagtgtggg cacggagcaa
    11821 aagggatcca tgcaggcggt tgccgggtcc ggcacgagca
//
LOCUS       DAOQPD010000102        11556 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_2885_length_11556_cov_21.854708, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000102 DAOQPD010000000
VERSION     DAOQPD010000102.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 11556)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 11556)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11556
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2885_length_11556_cov_21.854708"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..341)
                     /locus_tag="PK063_16865"
     CDS             complement(<1..341)
                     /locus_tag="PK063_16865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BCAM0308 family protein"
                     /protein_id="HMZ98775.1"
                     /translation="MMTNQPEGGHSARRDRFVEEYKHDSYKMPGKLKEPAVCKTCGAL
                     YHKGRWTWEIKPADAEQITCPACLRIQDKNPKGFVTLKGPYKAQHRDQVMGLIRNTEA
                     QEKKAYPLARI"
     gene            complement(392..1045)
                     /locus_tag="PK063_16870"
     CDS             complement(392..1045)
                     /locus_tag="PK063_16870"
                     /inference="COORDINATES: protein motif:HMM:NF012383.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase"
                     /protein_id="HMZ98776.1"
                     /translation="MFKNREEAGELLAQELVAFRNAPDGILLALPRGGVTVAYQLSLA
                     LHLPLDVLITRKIGAPGNPEYALGAVSETGAVYWNQEALSGLSLSERDLAVAVHAQQI
                     EVSRRVALYRQGRPFPNLKDRTAIIVDDGLATGATFFASVATVRQARPRRIIGAIPVG
                     PRSTIQEARSLVDQLVVLRVPEPFYAVGNFYRDFEQVEDREVLQYLNLAEEAFLSKS"
     gene            complement(1100..1246)
                     /locus_tag="PK063_16875"
     CDS             complement(1100..1246)
                     /locus_tag="PK063_16875"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98777.1"
                     /translation="MFKHPRYLDIPWEMHWHPEETSHHWWLILLVIIAALFLIGVGVT
                     SGLW"
     gene            complement(1262..1735)
                     /locus_tag="PK063_16880"
     CDS             complement(1262..1735)
                     /locus_tag="PK063_16880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HMZ98778.1"
                     /translation="MSGLTRWEPFRTQMNPWRELEEVQKRLSSMWGGAPQKEGSQKES
                     ISVAEWSPLVDITEDEKEYLIKAELPEMKKEHVKLTVHDNVLAISGERKYEKEEKDTK
                     YHRIERAYGSFMRSFTLPEDADGSKVSAEYKDGILNVHLPKSAQVKPKSIEVKVS"
     gene            complement(2321..3001)
                     /locus_tag="PK063_16885"
     CDS             complement(2321..3001)
                     /locus_tag="PK063_16885"
                     /inference="COORDINATES: protein motif:HMM:NF021631.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HMZ98779.1"
                     /translation="MTHPPSPPTDTCILKVVVGSHAHGLARPDSDKDFRSVFVLPTAE
                     LLRIGFKYQGTRMMKEEDDETAWEIGHFLQLALQGHPLVLETLVAPVVAMDDWGAELR
                     QLFPRLWSAQTAYDAFLNYCDNQRKKMLEKKDSRPEKYAAAYVRVLFNLCELLERGTF
                     SIRISETPVGEAVVKIKAGQFRPGEVIDMGEHWRAEATRRLHTCSQKAHPEIADAFLL
                     RVRKAFLT"
     gene            3173..3391
                     /locus_tag="PK063_16890"
     CDS             3173..3391
                     /locus_tag="PK063_16890"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98780.1"
                     /translation="MTTHETDIVRDGCLRCGGFMVPEEIREVNQMGWRCVMCGEHIDS
                     LILEHRRKMATPEGARQLLEKRDKARLN"
     gene            4123..4464
                     /locus_tag="PK063_16895"
     CDS             4123..4464
                     /locus_tag="PK063_16895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98781.1"
                     /translation="MATVLLSGVAPVMAEGDQDWLDTMVQAVLAEQVKDGSAEEFLSP
                     YVAQLAAVRSHLLNGESEAVYRTMNRFMEMLQAREAGISAEAADRLFDYCYLVTPPRY
                     HDVSRHLHRLS"
     gene            complement(4574..5011)
                     /locus_tag="PK063_16900"
     CDS             complement(4574..5011)
                     /locus_tag="PK063_16900"
                     /inference="COORDINATES: protein motif:HMM:NF012264.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HMZ98782.1"
                     /translation="MLTRLCCAGLVLALCLSTTPSRTLAESGGTGAPLKGDAARGQVL
                     FNGKGICHYCHGVDGVIDKKPSLKPETVAAIAKHAASAPDLRNRAVHTLKDNKARFRA
                     IREGHPGSGMFPDSTLSDQEITDLLAYLAALRQSASAPAKSPY"
     gene            5235..5624
                     /locus_tag="PK063_16905"
     CDS             5235..5624
                     /locus_tag="PK063_16905"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98783.1"
                     /translation="MTTPKGPSKTGKIKKSTTSSSPLARKALAAKWRQKKDDVSAAME
                     GSQRQGAMETSPKISAALVRTVEAAKLRRKKEMITGAMEKSQRGTDNHGKSQSEALAR
                     TVAANERLRTKTVITAALKESQRRSGS"
     gene            5763..6431
                     /locus_tag="PK063_16910"
     CDS             5763..6431
                     /locus_tag="PK063_16910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ98784.1"
                     /translation="MFEGDFQQRRTRVLIADEMALIAAGTRALLEPDCDVVGTVADGR
                     ALLSEAETLRPDIIVMEILLPLLNGLDALRPLVRKVPESKIVLLTAQESSWHVAEAFK
                     AGASGYVLKRSQPSELTQAIHAVLMGQWYLTPLIAKNVVKQDVGGEQPKRKVPTVSTL
                     TPRQREVLQLIAEGRGTKEVATLLNIAVKTVEFHKFRIMDQLNLHSTVALAKHAIIEG
                     LVRL"
     gene            6588..8573
                     /locus_tag="PK063_16915"
     CDS             6588..8573
                     /locus_tag="PK063_16915"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98785.1"
                     /translation="MIPPSAAIRVCIDCLLMMALLMIAPGELHAIQIEPNPNPDANTI
                     TITPSTPRENLVPFTNVGTINIEPLASFHNANQFNNSGVINNRGTITNSGTFTEVVRP
                     FPNPGGGFLGLGEGSQFINLASGVYNGGDRTTGIGGTFVNEGAVTHGLGFIRVGETGQ
                     YIQRQAVGSFVTPTTITPDAPFTNAGRIHIAAGDFNIDPISIRAAVSRYEQASTGTTQ
                     IDARFQNIGGEVHNAGTITVGSTGEYRQEGFPGPILAGSTTNTGTFTNAGTTNIGTGV
                     FTNQGSVANSGMFTVEAGGTYSQSRGDGTGAPVASTSNSGTFANAGQVRIGEGTSFGN
                     FSNRTPPVGQYIQQASGTTQIYGTFQVGGARVENAGLMTVGTTGTYLQAFNKFVPVVS
                     TTVNSGIFTNAGSTRVDAGTFTNHGSVVNSGTFQIAVNGVATLINHGTVVNSGTFEVG
                     AGVGAVGGVSGTGSYSQTTSVAHTIVNGTFGNTISLQAGSLSGTGTITGAVVNTGGVV
                     QPGTSLVPGTLTLANYTQGIYGRLDLKIGGLLAGSQYDVLKVTGSGTFGGSLSVRLIN
                     GFTPGLGNTFSLLTCSLGCTGLNSGTLFGGGVSLPSLASGLAWLSGLTNGGNSFSLTV
                     VASAASAPEPSTLLLIASGFVYLVIWQWRQLRSVHRS"
     gene            8836..9636
                     /locus_tag="PK063_16920"
     CDS             8836..9636
                     /locus_tag="PK063_16920"
                     /inference="COORDINATES: protein motif:HMM:NF019225.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-CTERM sorting domain-containing protein"
                     /protein_id="HMZ98786.1"
                     /translation="MNRCNWKKLSLSLMCVAILGLTAPLAQTTAHAVPLYGFTGHDVP
                     FSASPVISATVNYAVLPPFDPFGSMLSQLYVPAAGNPGFDSSKYTYLYQIANPASSHA
                     IWGSFQPQMSVVTPVSATSTGSFASGDLRLDFLNGGSLVNASGNNLQSTHSFGIGART
                     VSGAERIEILSNPLGGRSHPYSTFLNQGLTPGFTSQLFGFQSSNGPTFTTGLLQGDIF
                     APGSSFAAPVSLFATVPTAGAPEPGTMLLIGTGALSLLAWRWKKPSEP"
     gene            9639..10061
                     /locus_tag="PK063_16925"
     CDS             9639..10061
                     /locus_tag="PK063_16925"
                     /inference="COORDINATES: protein motif:HMM:NF024824.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ98787.1"
                     /translation="MFAKPTWVRVLPALYLVALVTSCSEPLSEQAAKHEMRGDGYVQQ
                     EQFREAVIEFKNVVRAAPDNPSLQWKLAKAALKGGDPSTAYQALGRVVQLDPSHFEAK
                     WSLGDLYLAGGKMDEVGKIAEELVSAQRPIALVTPPTT"
     gene            10388..11323
                     /locus_tag="PK063_16930"
     CDS             10388..11323
                     /locus_tag="PK063_16930"
                     /inference="COORDINATES: protein motif:HMM:NF019225.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-CTERM sorting domain-containing protein"
                     /protein_id="HMZ98788.1"
                     /translation="MKRSQVFLVIAVTFCVVICTWQSSYAAGFSLDQLRDNFIANIND
                     GNFILPKTSTGGLVTADFTSELAAGSRVGLAGAKAGFIAITGVNGGILGGIAGSFVPG
                     LGTAVGAGIGATIGLAAADRFVTTLNSGRVGDPFVADALLVKSISVGDKNVTQEVMAL
                     GQANVQRTIGLAGPSPGSFSFIAPSIFSPKLLDASGAVVSKVLGVDTFILNSPLGRSV
                     GVVAYNDPQITGRTVQRTDLFALNLLQITDQPVGTRFALTATPFVVAATVKEQLIDAA
                     PEPGTLLLVASGMVGFGGWRRRVAGRFTLSASDQV"
BASE COUNT         2422 a         3079 c         3385 g         2670 t
ORIGIN      
        1 ataatacgag ccaggggata ggccttcttt tcctgggcct cggtattgcg gataagtccc
       61 atcacctgat cacgatgctg agccttgtag gggcctttca acgtcacgaa gcccttgggg
      121 ttcttatcct ggatacggag gcacgccggg caggtgatct gttcggcgtc ggccggcttg
      181 atctcccagg tccatcgacc cttgtgatac aaggcaccgc aagtcttgca gacggcaggc
      241 tctttcagct tgcccggcat cttgtatgaa tcgtgtttat attcttcgac gaaacgatcg
      301 cggcgcgcgc tgtgaccgcc ttctggttgg ttggtcatca tgtccagtcc ctttcttggc
      361 tcgtctgcca accgttacgg caactccaga cttacgattt cgagagaaat gcttcctccg
      421 ccaggttgag gtactgcaac acctccctgt cttcgacctg ctcaaaatcc cggtagaaat
      481 tcccgacggc gtaaaatggc tcgggaaccc ggagcaccac taattgatcg acgagactgc
      541 gggcttcctg gatcgtgcta cgcgggccga ccgggattgc accgatgatg cgccgcgggc
      601 gggcctggcg cacggttgcg acggaggcaa aaaaggtcgc gccggtggcg aggccgtcgt
      661 ccacaataat ggcggtccgg tctttcagat tggggaaggg ccgcccttgc cggtatagcg
      721 ccacccgccg ggacacttct atttgctgcg cgtggacggc taccgcgagg tcgcgctctg
      781 aaagggaaag gcctgagagg gcctcctgat tccagtagac cgcgcctgtt tcactgaccg
      841 cgccaagcgc atattccgga ttcccgggcg cgccgatctt ccgggtgatg agcacatcaa
      901 gcggaagatg cagggccaga ctcagttgat aggccaccgt gacgcccccg cgcggaagcg
      961 cgagcaggat gccgtcgggg gcgtttcgaa acgcgacaag ctcctgtgcc agcagttcac
     1021 cggcctcttc acggttttta aacatgaccg tccgttcctc tatgcgctgg ccgatcaact
     1081 ggccacaccg tgagtcgagt caccacaatc cgctcgtcac cccgacgccg atcaaaaaca
     1141 gggccgcgat gatcacgagc agtatcaacc accagtggtg actggtttcc tccgggtgcc
     1201 aatgcatttc ccacggaata tccagatagc gaggatgctt aaacatgagc gctcctttcg
     1261 ttcaggagac cttcacctcg atggatttcg gtttgacctg cgccgatttc gggagatgca
     1321 cattgaggat cccgtctttg tattctgcgg agaccttgct gccgtcggca tcttccggga
     1381 gggtgaaact ccgcatgaaa ctcccgtacg cgcgttcaat acgatgatat tttgtgtcct
     1441 tttcttcctt ctcgtacttg cgttcgccgg agatggccag cacattgtcg tgcaccgtca
     1501 gcttgacgtg ttctttcttc atctccggca gttccgcctt aatcagatac tctttctcgt
     1561 cttcggtgat gtccaccaga ggtgaccatt ccgcgacgga gatggactcc ttctggcttc
     1621 cttccttctg cggcgctccg ccccacatgg atgagaggcg tttctggact tcttccaatt
     1681 ctctccaggg attcatctgt gtgcgaaatg gttcccagcg agtcagtccg ctcatggccg
     1741 tactccttta tctattctgg tgatttcttg gtttcgatga gtcccacagg tctccatgcc
     1801 tcggagtatt gcaggcacga tgccagaatg ccgggtgaac gtatggcctt cctggagccg
     1861 cgaagtccat tcgcctggca gaaaaatgcc tgcgacatgg tcctgccagt ggggcgatac
     1921 gggacagcgg caggcaccgg caatggtgcc aattacctca ttgatttcga ggcgaccatg
     1981 cttagctaga tccttgaagg gaggtggagc caggataagg tcgacatccc cgcttccgtg
     2041 cagcgaagag ttggttcggg gattgcgcct gtgccggttt cgggatcagt tctgaaggga
     2101 cgcgcttcca tctcggtgcc agtatgaggc acggctccca tggagcccga tgaacgggag
     2161 gcgcggaaca tccggtatga gagttgtgcc gggatgttca gatggatctc gctcggtcgg
     2221 caggcctgat ctctacacgg aagcgggttc ttttttggcg gggcaggggt acgtcccgat
     2281 tgcccggatg tctaggatct gagggggaga ggttgtggat ttatgtgagg aacgctttgc
     2341 gaaccctgag gaggaaggca tcggctattt cagggtgggc cttttgagag caggtgtgta
     2401 gccggcgggt ggcttctgct ctccaatgtt ctcccatgtc gatcacttct ccggggcgaa
     2461 attgcccggc cttgattttg accacggctt caccgaccgg agtttcggag atcctgatgc
     2521 tgaaggttcc tcgttccaac aactcacaca gattgaagag cacccgcacg taggctgcgg
     2581 cgtatttttc gggacggctg tcttttttct ccagcatctt ttttcgttga ttgtcgcagt
     2641 aattcagaaa ggcatcatag gctgtctgcg ccgaccagag acgcggaaat aattggcgca
     2701 gctccgctcc ccaatcatcc atggcgacga ccggggcgac cagcgtttcc agcaccaacg
     2761 gatggccttg cagcgcaagt tggagaaagt ggccgatctc ccaggccgtt tcatcatctt
     2821 cctccttcat catcctcgtg ccttgatatt tgaagccgat acgaagcaat tcggcggtgg
     2881 gcaatacgaa gacgctgcga aaatccttgt cgctatccgg tctggccagg ccgtgggcat
     2941 gtgagccgac gacgactttc aggatacagg tgtcggttgg gggcgaagga ggatgtgtca
     3001 tggttgcgat gtgccaactt gaacgaggcc gccgtccacg tcaagtgggt ttgagtgtgg
     3061 ttcagcattg tgggggcagg gctcgacccg tgtctgctga atccttttca tcagttcgtc
     3121 ctcccatgtg cagggcgacc atatcacgct caacagaaag gtgagagcat atatgacgac
     3181 tcatgagacc gatattgtcc gggacggatg tctacgttgc gggggattca tggtgccgga
     3241 ggagattcga gaggtcaacc agatgggatg gcggtgcgtg atgtgcggcg agcacatcga
     3301 ctcgctgatt ctcgaacatc ggcgaaagat ggcgacgccc gaaggcgcga ggcagctgtt
     3361 ggagaaacgg gacaaggcca gattgaacta gaacatccgg agggcaacgt cgtggccgac
     3421 attaaccggc aagattgatc cgtgcggccc aacggatcgc gagaggggag atgcgacacc
     3481 gattgcgccg cgaagccggg tgcaacaatt cgccttggag atgggctggg tccgatcctc
     3541 agcagaagtg gacaagccgt tgaggcaagg agaccttgtg aacgatgcgc cagctgtcgc
     3601 ggtgaggttt tgaaaagaag gccaagaaaa gaaataaacc ggcggaggtt ggtccagaga
     3661 gggtctttca actcttgaga tcttggaggg gtttcaggct tcccgcttcg cacctgcggg
     3721 cctgctcacc acccctgcac tcgatcccga taccgtttcc gttcctctca ccccaaccct
     3781 ccgctcactt ataaggtaag gctggtacgg cagcggtcaa gccgtggccc tcgatgaagg
     3841 gcccttccac agagcacatc cttcgctgtc gcgtaatagg gcagccccat gaagaccaga
     3901 gcgccacccc ttcctattcc catccggtcg atggccaact ccttgtgtgt gcgtctgttc
     3961 tcggtgtccg aagggctgtg cgtgtactgg tggctgtact cggccttggc ataacctatg
     4021 ctgcgttcag tattcgtagt gctactggag ccctcgtcaa agcgggaggt gactatgcga
     4081 atcagccgag acataacgcg gatggcgtcg ttatgcatct tgatggcgac cgttctcctc
     4141 tccggtgttg cccctgtgat ggctgagggg gaccaggatt ggctcgatac gatggtgcag
     4201 gcggtgctcg ccgagcaggt gaaagatggg agtgcggaag aatttctttc gccgtatgtc
     4261 gcacagctgg cggccgtgcg ttcacatctg ctcaacggcg aaagcgaagc tgtgtaccgg
     4321 acgatgaatc ggtttatgga gatgcttcaa gcacgggagg caggaatttc agcggaggcg
     4381 gcggatcggc tcttcgatta ttgttatctc gtcacgccgc cgcgctatca cgatgtctcc
     4441 cggcatctcc accggttaag ttgaagcccg ttggattgcg agagcggtct gaggttggca
     4501 caggcgaaaa cgtttccgca cagagtggtc atgtgcgatg tgcacggtgt tccggtaagg
     4561 ctaccaacga cgattagtat ggacttttgg cgggagcaga ggcgctttgc ctgagtgccg
     4621 caagataagc caagaggtcc gtgatctctt gatcgcttag cgtggagtcg ggaaacatgc
     4681 cgcttcccgg atgcccttca cggatcgccc gaaagcgggc tttgttgtct tttagcgtgt
     4741 ggaccgcacg attgcgcaga tccggtgccg aagcagcgtg cttcgcaatt gcggccacgg
     4801 tctctggttt gagtgaaggt tttttgtcga tcactccatc gacgccgtgg cagtaatggc
     4861 aaatgccctt gccgttaaag aggacctggc ctcgcgcggc gtcacccttc aggggagcgc
     4921 ccgtacctcc cgactcagcg agagtccggc tgggtgtggt ggacaaacaa agggccaaga
     4981 ccaatccagc acaacagagt cgtgtcagca tcacgtggtg tccttaggca gagagtaaag
     5041 gcaggctcag tatgccgcgt cgataggtgg aacacaatgc cgtcgaccca cagactgtca
     5101 tgcgtcttga tcgatgaggt atgaggtgtc agcgtgcccc ctccacggaa tggcttggta
     5161 tactgtggga tatttgtggc gcggctgtga ggctgcatga cacccaccca gtcctgacga
     5221 ggagggaaaa caccatgacg acaccaaaag gtccctcgaa gaccggcaag ataaaaaaga
     5281 gcaccacgtc atccagtccg ttggctcgca aagctctggc ggccaaatgg cgacagaaga
     5341 aagacgacgt gagcgcagca atggagggct cacaacggca aggggcgatg gaaacctcgc
     5401 cgaaaatttc agccgcgttg gtgcggaccg tggaagcggc gaaactcaga cggaagaaag
     5461 agatgattac aggtgcgatg gagaagtcgc agcgagggac cgataatcat ggcaaatcgc
     5521 agtcggaggc cttggcgcga acggtggcgg cgaacgagcg tctgcgcacg aaaaccgtca
     5581 tcacggcggc gttgaaggag tcacaacgtc ggtcgggttc ctgaagattg tcaggtgggt
     5641 tttctcatcc cgtggatagc agtacgtaag aggagaggcg acatctgtga agtcctatct
     5701 gcgctatagt tgcgtctgcg tccgaaacgc ttcaggatcg aatcagctaa acgagaagac
     5761 ccatgttcga aggtgatttt cagcaacgca ggactcgagt acttattgca gatgagatgg
     5821 cgctcattgc agccggcact cgcgccttgc ttgagccgga ttgcgatgtt gtgggcactg
     5881 ttgccgatgg acgcgcgctc ctcagcgagg ctgaaaccct gcgccctgac atcatcgtca
     5941 tggagattct ccttcccttg ctcaacggat tggacgcgct tcgtcccctg gtcagaaagg
     6001 tgcctgaaag taaaatcgtc ttgctgaccg cccaggaaag ctcctggcac gtggctgagg
     6061 cattcaaagc cggtgcctcg ggctatgttc tgaaacgttc gcaaccatcc gaattgactc
     6121 aagctattca tgccgtattg atggggcagt ggtatctcac tccactcatt gccaaaaatg
     6181 tggtgaagca ggatgtaggg ggtgagcaac caaagaggaa ggttccaaca gtgtctacgc
     6241 tgactcctcg ccagcgtgaa gtgttgcagt tgatcgcgga gggacgggga acgaaggagg
     6301 tcgccacgtt gctcaatatc gcggtcaaga ccgtcgagtt ccacaagttc cgcatcatgg
     6361 accagttgaa tctccactcc accgtcgcgt tggcaaaaca tgccattatt gaaggacttg
     6421 ttcgcctgta ggtggtgtta ctcctcacct ttctgtttgt gcggcctcaa gtaaacttcc
     6481 cagttcccac ctgtccacat tcggcgtagg gtactgaccg gattctgaga gtgcccgctc
     6541 gtgcgttcag cgctgagccc gacagccggt ccggaaggag gtcgaacatg attcctccct
     6601 ctgctgctat tcgtgtttgt atcgactgtt tgctgatgat ggcgttgctc atgatagctc
     6661 cgggcgagct tcatgccatt cagatcgaac ccaatccgaa tccagacgca aacaccatta
     6721 cgatcactcc ttccacgccg cgcgaaaatc ttgtcccgtt caccaacgtt ggcacgatca
     6781 atatcgagcc gcttgcctcg tttcacaatg cgaatcagtt caacaattcc ggcgtcatta
     6841 acaatagggg caccatcact aattcgggta cgtttaccga agttgttcgt cccttcccca
     6901 accctggtgg tggtttctta ggtcttggtg aaggatcgca attcattaac ctggcgagtg
     6961 gcgtgtataa cggcggcgat aggaccaccg ggattggagg cacctttgtc aacgaaggcg
     7021 ccgtcactca cggccttggc ttcattagag tgggcgaaac aggccaatat attcagcggc
     7081 aggctgtggg ttcgttcgta acgccaacga cgattacccc cgacgcgcca tttacgaacg
     7141 cggggcgcat ccacatcgcc gccggtgatt tcaacattga tccgattagt attcgtgcgg
     7201 ctgtctcgcg gtatgagcaa gcttcaaccg gcacgactca aatcgatgcg aggtttcaga
     7261 acataggcgg tgaggtgcac aacgcgggga cgatcacggt cgggtcaact ggtgagtatc
     7321 gtcaggaagg ctttcctggt ccgatcctgg ccggaagcac tactaacact ggcaccttta
     7381 ccaatgcggg caccacaaac attggtacag gtgtcttcac caatcaaggc agcgtggcaa
     7441 actccggcat gttcactgtt gaagcgggag ggacatatag ccagtcgcgg ggagatggta
     7501 ccggggcccc agtcgcatcg acctccaata gcggcacttt tgccaacgcg ggccaggtgc
     7561 gtatcggtga ggggacgtcg ttcggcaact tctccaatcg gacaccacca gttggtcagt
     7621 atatccagca agccagcggc accacacaaa tctacggtac gtttcaggtc ggtggtgctc
     7681 gtgtggaaaa cgccgggctc atgaccgtgg ggacgacggg aacctacctt caggcattca
     7741 acaagttcgt tccggtcgta tccacgaccg tcaacagcgg catcttcacg aatgcgggca
     7801 gcacgcgcgt cgatgcgggg acttttacca accatggcag cgtggtgaat tccggaacgt
     7861 ttcagatagc ggtcaatgga gtggcgacgc tgatcaatca tggcacagtg gtaaattctg
     7921 gaacatttga ggtcggggct ggtgtcgggg ctgttggagg agtttctgga accgggagtt
     7981 attcgcaaac tacttcggtg gctcacacga tcgtcaatgg aacatttggc aatacgatca
     8041 gccttcaagc gggtagcctc agtggaacgg gcaccattac cggtgcagtg gtgaacactg
     8101 gaggggtagt tcaaccgggg accagtcttg tgccggggac gctgacgctg gcgaactaca
     8161 cccaaggcat ttatggaaga ttggacttga agatcggtgg cttgctggcc ggatctcaat
     8221 acgatgtgct gaaagtcaca ggttcaggga cgttcggcgg cagtctttcc gtgcgattga
     8281 tcaatggatt tacaccggga ttggggaaca cctttagtct gctcacctgc tccctcggct
     8341 gcacgggatt gaatagcggc acgttatttg gaggcggcgt ttcgctgccc tccctggcat
     8401 cggggcttgc ttggctcagc ggactcacga acggaggcaa cagtttttcg ttgacggttg
     8461 tcgcctcggc ggcatcagca cccgagcctt cgacgctgtt gctcatcgca tccggatttg
     8521 tttatctggt catctggcag tggaggcagt tacggtccgt gcataggagt taggagagct
     8581 caatcgagtc gtggacggga gatacagcct gaaccactcc tttccttcta tgcctccttg
     8641 ctagcatgct atggcgagga acctccctag ttcccaaact tgcgcactcc ccttagagtg
     8701 cacacagtac aaggggcgcc cacagcgaaa ggacgcgttc ggaagcatgg tcgatgctgc
     8761 acggggtgca ttggctgcac tacgcgctgc tcatgtaagg ctgaaatgga tttgtgtggg
     8821 aagggaatga gattcatgaa tcgatgtaat tggaagaaat taagcctgtc cctcatgtgt
     8881 gtggctatct tgggtttgac tgcgccactt gctcaaacaa ctgcccatgc tgttccgctg
     8941 tacggattta caggccatga tgtgccgttt tccgcatctc ctgtgatatc ggcgacggtg
     9001 aattatgctg tcctgccgcc gttcgacccg ttcggcagta tgttatctca actttatgtc
     9061 ccggccgcgg gtaatccagg gtttgattcc agcaagtaca cctatcttta tcaaattgcc
     9121 aatcccgctt cttcccatgc gatatggggt agctttcagc cgcaaatgtc cgttgtgaca
     9181 cctgtgtctg caacctcgac aggatcgttc gcgtcaggag acctgcgcct tgattttctc
     9241 aacggcggct ccctcgtgaa tgcgagcggc aataatcttc agagcactca tagctttgga
     9301 attggagcgc gaacagtctc aggcgctgag cggatagaaa ttttgtccaa tcccttaggt
     9361 ggccgctccc atccctattc aacattcctc aatcagggcc tgacccctgg tttcacaagc
     9421 cagttattcg gctttcaatc tagcaacggt cccacattta cgaccggact attgcaggga
     9481 gacatcttcg caccgggaag tagcttcgcg gctcctgtaa gtctattcgc caccgttccc
     9541 acggcgggtg ctcccgaacc gggtacgatg ttgctgatcg gcaccggcgc cctcagcctt
     9601 cttgcttggc ggtggaaaaa accaagcgag ccctaaaagt gttcgccaaa ccaacatggg
     9661 tcagggtttt acccgctctc tacctggtag cgctcgtgac ctcctgctct gagccactgt
     9721 cggagcaggc cgcgaagcat gagatgcgcg gtgacgggta tgtgcagcag gaacagttcc
     9781 gcgaagcggt gatcgagttt aagaatgtcg tgcgggctgc tccggataat ccttctctcc
     9841 agtggaaact cgcgaaggcg gcgttaaagg gcggagaccc atccacagcg taccaggcgc
     9901 tcggtcgggt ggtgcaactc gatccgtcgc atttcgaggc gaaatggtcc ctcggcgatc
     9961 tgtatctggc cggagggaaa atggacgagg taggcaagat tgccgaagag ctggtgtcgg
    10021 cccaaaggcc gatcgcattg gtaacacctc caactacgta agcaagctgg cgacatacgc
    10081 catctgcgct tcgcgctatg tttgccccag gatccataac gcatcattga tccacagaat
    10141 gaacccatgt tggagtgtga tcaccaacgg cgtagaccgc gtctcctcat cacggatgat
    10201 ttaccggttt gtccagttgg tcgagcctga ttattgtgtc gtcggggctg ttgaggaggg
    10261 ccgggtgttg ctcgtggagg tcaagacgtt gaggcctgac attattgtga cggaaggtca
    10321 tctgccattg ctaaatgaca gatgacatga attccaaagc ttggattttg attcacaagg
    10381 aggagttatg aaaaggtctc aggtcttcct agtgatagca gtgacattct gtgtagtaat
    10441 ttgcacgtgg cagtcttctt atgctgcagg gttctcgcta gaccaacttc gtgacaactt
    10501 catcgcaaat attaacgatg gcaacttcat ccttccgaaa actagcactg ggggactcgt
    10561 gaccgcagat tttacgtcgg aactcgctgc cggctctcgg gttggtctag caggagccaa
    10621 ggcggggttt attgcgataa ctggtgtgaa tggtgggatt ttaggaggta tcgccggctc
    10681 ctttgttccc ggcttgggaa ccgctgtggg ggcgggaatt ggcgctacaa taggcctcgc
    10741 cgccgccgac cgtttcgtaa ccacactcaa ttctggccga gtaggtgatc cattcgttgc
    10801 cgatgctctc ttggtcaagt caatatccgt tggagataaa aatgttaccc aagaagttat
    10861 ggctctaggc caagctaatg tccaacgtac cattgggctt gctggaccat ctccgggctc
    10921 attctccttt atagccccaa gcattttttc gcccaaattg ctggatgcat caggtgctgt
    10981 tgtttctaaa gttcttgggg tcgatacatt tattcttaac agcccacttg gaaggtcagt
    11041 tggtgtagtc gcctacaatg atccccagat tacgggaaga acagtacaaa gaacggatct
    11101 cttcgcgctc aacctgttac aaataacgga tcagcctgtt ggaactaggt tcgcactaac
    11161 tgcgacgcct tttgtggttg cagcaacagt caaggaacaa cttattgatg ccgcccctga
    11221 gccaggtacg ctgttgttag tcgcctctgg aatggtcggc tttggcgggt ggcggcggag
    11281 ggtggcaggg aggtttacac tatcggcaag cgatcaggtc tgaggtcgtt cggcaggagg
    11341 gaggctctcc tggcatatcg cctgactgat gcctcggcga agctgaagta ccttctcgcc
    11401 tggaggtttc cgatgacaag atgggtcgtt cactgctgcg ctctgattct tttggtcttt
    11461 accttatcct gcgccaagac tccatccgag caggctgcga agcatgaggt gcgcggtgac
    11521 gggtatgtgc agcaggaaca gttccgcgaa gcaatg
//
LOCUS       DAOQPD010000103        10976 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_3093_length_10976_cov_23.029301, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000103 DAOQPD010000000
VERSION     DAOQPD010000103.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 10976)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 10976)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10976
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3093_length_10976_cov_23.029301"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            76..231
                     /locus_tag="PK063_16935"
     CDS             76..231
                     /locus_tag="PK063_16935"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98789.1"
                     /translation="MGVMPRGMTERKGDAMKQVISLAPVMLLMVLVMGAMGIMVFWGL
                     SLLDLSE"
     gene            251..1270
                     /locus_tag="PK063_16940"
     CDS             251..1270
                     /locus_tag="PK063_16940"
                     /inference="COORDINATES: protein motif:HMM:NF012695.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HMZ98790.1"
                     /translation="MREEGDHPGRRWAIILAGGDGVRMQPVVKRWLGRTMPNHYCRYV
                     GTRSLFQHTLDRMRYVTSPARTLVVVGRGHQEAWAQIGQRHPGMVLVQPRNAGTAAGL
                     FLPLTYIRARDPAGMVVVTPANQFICPDERLPAEILYAVRAAEKLPANLVGLAARPDG
                     PDSEYAWIKSGHELVRLGLRSIRAVNTFLHRPEPDLARLAYASGALWHTGIMAASVET
                     WWNLGRRVLPEMMRLFERLGEVINTPREPQALRDIYARMPVRSFSRDLLAAVPGVAAV
                     MEMQGVWWSDWNHPERIMKTLTRLGRDTASVMPHLRAAVAERQSAQTLDIAMAHRTDG
                     WSAEG"
     gene            1607..2587
                     /locus_tag="PK063_16945"
     CDS             1607..2587
                     /locus_tag="PK063_16945"
                     /inference="COORDINATES: protein motif:HMM:NF012791.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HMZ98791.1"
                     /translation="MTTPPFVKHILFATDFSDDASRAQEYAVHLAGACDAKLDVLHVI
                     EAPHEMQADAESLGIVGRSRDAAARQLEEVRDELARRGTPARVRLLLGNPSEHIHQAA
                     REQNIDLMVLGAQGRTNVLYGLIGKTAERLIHEGPCPVLAVPGSRQDAVEMPPTDRPA
                     LIRHILAPLDFSTPSLDAVEYAVHLAKGVGATVTLMHVLEPASYDLDCGLGVIEEESS
                     KRDYWNRQLMDLRDVVTAFDLQADVALCGGVPSDAILASALRQHADLIVMGTHGRRGI
                     SPDRCGSVAEAVLRRATCPVLTVKTGKFDPGHRRVVPNALERHVTRGENA"
     gene            2584..2997
                     /gene="rnk"
                     /locus_tag="PK063_16950"
     CDS             2584..2997
                     /gene="rnk"
                     /locus_tag="PK063_16950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0070063 - RNA polymerase binding [Evidence
                     IEA];
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside diphosphate kinase regulator"
                     /protein_id="HMZ98792.1"
                     /translation="MNPRNICMTAVDLSRLRDVLRARTSVGRDRDHLDSLEEELDRAD
                     VVDPSAIPPNVVTMNSRVRIEDVDTGMENVYTLVFPSDASIAERKISILAPIGTALLG
                     SRVGSTVDWPVPAGRRTMRIKDVLYQPEAAGDYHL"
     gene            3135..3569
                     /locus_tag="PK063_16955"
     CDS             3135..3569
                     /locus_tag="PK063_16955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HMZ98793.1"
                     /translation="MDVRSKVYTYRTAVQWTEQKKGTISSEGKPDIQVATPPEFKGHA
                     GIWSPEDLYVAAANICLMTTFLAVAERGGLAFTAYHCEAEGRLELVEGKFQVTVITLR
                     PHITLSPGGDASKAKELIEKAEANCLISNSMKTRIALEPTIV"
     gene            3783..4148
                     /locus_tag="PK063_16960"
     CDS             3783..4148
                     /locus_tag="PK063_16960"
                     /inference="COORDINATES: protein motif:HMM:NF024834.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HMZ98794.1"
                     /translation="MHLRIGVIAVSQLILLSAIVVAVYAGPGNVGKGKTLYANLCIRC
                     HGVDGKGKGEMTFTPPVADLTAPAAQTKLDATLLKTIHDGRRDTAMGAWKFVLSEEEM
                     RDVTAYLRQLGSEAGRGRP"
     gene            4168..4635
                     /locus_tag="PK063_16965"
     CDS             4168..4635
                     /locus_tag="PK063_16965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98795.1"
                     /translation="MNWRIFGWGIAALWMITIGIMSTFLVQGHTRPGDDGRTEIILAP
                     SERDLVLAEMRGLLKAIHGVVTVLGAGDQPLKAAESSARAAGMAMAADVNPAIMLKLP
                     LAFKQMGMSIHKDMDHLADAIAQGESQVHILNRLSSITARCTTCHDMYRFGTP"
     gene            4734..4952
                     /locus_tag="PK063_16970"
     CDS             4734..4952
                     /locus_tag="PK063_16970"
                     /inference="COORDINATES: protein motif:HMM:NF022577.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2892 domain-containing protein"
                     /protein_id="HMZ98796.1"
                     /translation="MACNVGGVERPVRIVLGILLIGIGVFGALPPVGMGIALAAGTIA
                     LVTGALGFCPLWSLFGINTCSVGAGKKA"
     gene            4987..5541
                     /locus_tag="PK063_16975"
     CDS             4987..5541
                     /locus_tag="PK063_16975"
                     /inference="COORDINATES: protein motif:HMM:NF012575.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinol-cytochrome c reductase iron-sulfur
                     subunit"
                     /protein_id="HMZ98797.1"
                     /translation="MVSHAEQPDQQPEGGFSTPVGSRRTFFQWVTLAAAGLVGVGLSI
                     PLLSTLISPAFHRRRRDWVDVGAVDDLSSGHPKQLDHVTTIRDGWLETTSHKAVWAVK
                     QAQGDIKVFSPICTHLGCGYRWDETDKKFLCPCHGSSYDVNGQVLGGPAPRPLDTLPS
                     KVEGGRLLVMYKDFKSGLPTSVEI"
     gene            5600..6925
                     /locus_tag="PK063_16980"
     CDS             5600..6925
                     /locus_tag="PK063_16980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b N-terminal domain-containing
                     protein"
                     /protein_id="HMZ98798.1"
                     /translation="MPSRLYDWLDARLNLKPVQRTLLDEPIPGGASWIYVFGSVTLFL
                     FVLQAATGMFLALYYAPTPDHAYDSVRFIETDVTLGWLVRGLHHWGASSMVVAIGLHM
                     LQTFLYGAYKAPREVMWMVGVVLFLIVMTFAFTGYLLPWDQTAYWATQIGINMVGTVP
                     LIGDVASRILRGGEILGALTLSRFFAIHVLFLPAMLVTGIAVHLFVLRRVGPAGPWTD
                     DRASLGAETFAPRQVYMDAVVIAGVFLVVAALAFSIPLPLTDKANPSDTSFVPVPEWY
                     FLFYYELLKYVHGPLEPLATWILPLCVILVMLFWPFIDRNPVRNPIRRPVALGSGLLF
                     LLVVFGLLGISIRNLYAVPRVDPAVARGRAVYAQLGCVGCHRIHGEGGAVAPDLSTVG
                     DTRPDREWHLKHFRDPQSVSPGSFMPKFPLTDQQLNDLTTYMLSLKRAT"
     gene            6964..7314
                     /locus_tag="PK063_16985"
     CDS             6964..7314
                     /locus_tag="PK063_16985"
                     /inference="COORDINATES: protein motif:HMM:NF012264.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HMZ98799.1"
                     /translation="MRIWGTLLCTVGVLLGSMPISLAASGKGNPATGKKLYHESCQNC
                     HGPAGKGDSEMAAYLTPAPADLTSKTTQEKTDAQLRKVIQEGRPGTAMTGYAAAFDEE
                     KLNDVMAYIRSLKP"
     gene            7556..8401
                     /locus_tag="PK063_16990"
     CDS             7556..8401
                     /locus_tag="PK063_16990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="c-type cytochrome"
                     /protein_id="HMZ98800.1"
                     /translation="MRHVLFSVIVIVGLTAGCVESKDTRGAAPSAVSQSDSARLDALF
                     SHPSPDSIPGGQRGEQIRLGYELVVHTQQFAAPYVGNRLTCANCHLDAGLDPNSASFV
                     GLSRAYPEYRARAGKVLTLADRINDCFERNLNGKAIPQDSHKLQAIVAYIEWLSKDVP
                     AGSRMAWRGVPTLSSTKPPDPANGAKVFTARCAFCHGADGQGTMAAPPVWGAQSYTIG
                     SDMARVSVAASFIKQNMPRTRGWALSDQEAYDVAAYINSQPRPDVAGRGRDWPKGEKP
                     ADAPN"
     gene            8485..8883
                     /locus_tag="PK063_16995"
     CDS             8485..8883
                     /locus_tag="PK063_16995"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF014608.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HMZ98801.1"
                     /translation="MKLSVAYQGGTRYDILSDRHRVVTDQPTEDGGTDAGMSPVELFV
                     GSVASCVGYFVGQFCARHDISREGLKVDAEWAVAEGPHRVGQIQLAIRLPHRVTPEQK
                     ERLLRVAHACTVHQSIMVPVQVAIELNPHT"
     gene            8915..10096
                     /locus_tag="PK063_17000"
     CDS             8915..10096
                     /locus_tag="PK063_17000"
                     /inference="COORDINATES: protein motif:HMM:NF012401.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite oxidase"
                     /protein_id="HMZ98802.1"
                     /translation="MAVTRRALFERVLQGLGAAVVAGGVDRAFADSQSDVIGQVSGPL
                     TVRVSRPFDAETPVREFGSWLTPNERFFVRSHFGPPGAETIQPEAWRLTVKGLVQNEL
                     TLTLSELRKFEQVTITAVLQCSGNGRAHHRPKVPGVQWERGAAGNAQWTGMRLRDLLQ
                     RAGVKPQGLHVQMQGADRPALPTVPLFTRSIPIAKAFHPDTLLAYEMNGRPLPLLHGA
                     PLRVITPGWMAESCMKWLTELTLRADETPGYYMQQAYRIPETSIQPGSGLPGSVMVPV
                     EQMPVKSLIAAPGEGDTLKAGPVTIQGVAWAGESPITKVEVSCDDGKTWEPARLLGEA
                     QPYAWRQWQYLWNARQVGPTTILCRATDAQGAQQPEKSPWNPGGFLWNGWDRLAVTVA
                     A"
     gene            10105..10740
                     /locus_tag="PK063_17005"
     CDS             10105..10740
                     /locus_tag="PK063_17005"
                     /inference="COORDINATES: protein motif:HMM:NF024834.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="c-type cytochrome"
                     /protein_id="HMZ98803.1"
                     /translation="MEGAQRERGRWSLLAAGLVLLLGIAAGTAAQEDDKHTIEPAQAR
                     RAVTLIHARCAVCHTTDLIVQQRLPPDRWQITVEKMMHWGADLSKDEAAALLQFVTAR
                     YHPGAPDHLPSIEEELALTAPAGGPSTASDGPLVGVPARGAEIFARNCQACHGEGAMG
                     GAGPKLARNKILKNEGVFWETVLHGRGPMPAWGSVLSHQEVADIHAWLASR"
     gene            10777..>10976
                     /locus_tag="PK063_17010"
     CDS             10777..>10976
                     /locus_tag="PK063_17010"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98804.1"
                     /translation="MGGRRTAMIGCALVILVGLFSFPRLLLGSDQTRVKEMIQNNCAG
                     CHRLEGKAESRFNLKAPDLIWAG"
BASE COUNT         2145 a         2980 c         3597 g         2254 t
ORIGIN      
        1 tcagcatgaa gaattcttca tgccctactc atcggcactt catctcgcgc cggtagagtg
       61 tggtgacgga atggcatggg tgtcatgccg cgcggcatga cagaacgaaa gggcgatgcg
      121 atgaagcagg tcatttcctt ggcgccggtg atgttgctca tggtcttggt gatgggcgca
      181 atgggaatca tggtcttctg gggcctgtcc ctgctcgact tatccgagta agacaccggg
      241 aggaggcgtc gtgagagaag aaggagatca tcccggacgg cggtgggcga tcatcctcgc
      301 ggggggagac ggagtccgca tgcagccggt cgtgaagcgc tggttgggtc ggacgatgcc
      361 gaatcactac tgtcgatatg tcggaaccag gtctctgttt caacatacgc tcgaccgcat
      421 gcgctacgtc acgagtcctg cgcgcacgct cgtggtggtc ggacgaggtc accaagaagc
      481 ctgggcgcag atcggtcagc gacatcctgg catggtcctg gtgcaacccc gcaacgccgg
      541 cacggcagcc ggattgtttc tgcccctgac ctatattcgt gcgcgggatc cggcggggat
      601 ggtggtggtt acgccggcca atcaattcat ctgcccggac gagcggttgc ccgcggagat
      661 tttgtacgcc gtccgggcgg cggaaaagtt gccggcgaac ctggtcgggc ttgccgcgcg
      721 accggatgga ccggacagcg agtatgcctg gatcaaatcc ggtcatgaac tggtcaggct
      781 gggccttcgc tcgatccgcg cggtcaacac cttcttgcac aggccggagc ccgacctggc
      841 gcggttggcc tatgcttcgg gagcgctgtg gcatacaggg atcatggcag cgagtgttga
      901 gacgtggtgg aatctcggcc ggagagtcct gccggagatg atgagattgt tcgagcgact
      961 gggcgaggtg atcaatactc cgagggaacc acaagccctt cgcgacattt acgcgcgcat
     1021 gccggtccga agtttctcac gggatctcct ggctgctgta ccaggcgtag ccgcagtgat
     1081 ggagatgcag ggagtatggt ggagcgattg gaatcatccg gagcgcatca tgaagacact
     1141 cacgcgtctg ggacgggaca cagcctcggt catgccgcac ctcagagctg cagtggcgga
     1201 gcggcaatcc gcgcagacgc tggatatcgc tatggcgcac cgtactgatg gatggtcagc
     1261 agagggatga cagatggcgg ccatgtgaac gtatggccga tcgattggcg ctgctccggg
     1321 cacagcgggg tgtatcgccc caccggtggg tagcggctgc cgcaaatgtc aacaatgcgt
     1381 gtggatcgcg gcaggggcac tagccggaaa tggaggctcg accgcggact tccgggcgga
     1441 ggtgaatgaa caagacgtgg cacttgtctt gcgtcaacga cacctgggtt cctcacgttc
     1501 atctctccat ggcatgagtc ccgcgctccg gttcagttct cggccggcgc tctccgatgg
     1561 acctccggcc gcccggaaca atcgtccaac ttgtgaagga gaagccatga cgacaccacc
     1621 attcgtgaag cacatcttat tcgccacgga tttttcagac gatgccagcc gtgcacaaga
     1681 gtatgcggtt catctcgccg gcgcctgcga tgcgaagctg gatgtcttgc atgtcatcga
     1741 ggcgccccat gagatgcagg cggatgcgga atctctaggc atagtgggtc gctcgcggga
     1801 cgcggctgcg cgacaattgg aagaggtgcg ggacgagtta gcgcgccgag gcactccagc
     1861 cagagtcagg ctgctactgg gaaatcccag cgagcatatt catcaggccg ccagagaaca
     1921 gaatatcgat ctgatggtgt tgggcgcgca gggacgcacc aatgtgctct atgggctgat
     1981 cgggaagacg gcggaacgat tgattcatga ggggccctgt ccggtgctgg ccgtgcctgg
     2041 atcgaggcag gatgccgtgg aaatgccgcc gaccgatcgg cctgcgctga ttcggcatat
     2101 tctggcgccg ttggattttt cgacgccatc gctggatgcg gtggaatatg ctgttcacct
     2161 ggccaagggg gtcggcgcta ccgtgacgct gatgcacgtg ctggagccgg cctcgtatga
     2221 tctggactgt ggtctcggtg tgattgaaga ggaatcgtcg aagcgagact attggaatcg
     2281 gcagttgatg gacctgcgag acgtggtgac ggctttcgac cttcaagctg acgtggccct
     2341 ctgcggcggc gtgccttccg atgccatcct ggcctccgcc ttgcggcaac atgccgacct
     2401 cattgtgatg gggacgcatg ggcggagagg gatttctccg gaccgatgtg gaagcgtcgc
     2461 agaggcagtg ttgcgccggg cgacctgccc ggtgttgacc gtaaaaacgg gaaaattcga
     2521 tccaggccat cgccgggtgg tgccgaatgc gctggagcga catgtcacca gaggagagaa
     2581 cgcatgaatc cccgtaatat ctgcatgact gccgtggacc tgtctcgcct cagagacgtg
     2641 ctgagggccc gcacgagcgt cggccgtgat cgggaccatc tggatagttt ggaagaggag
     2701 ctcgatcgcg ctgatgtcgt ggacccctcc gccattccgc ctaatgtggt cacgatgaat
     2761 tcacgagtcc ggatcgaaga tgtggatacc ggcatggaaa acgtctatac gctggtgttt
     2821 ccttcggacg ccagcatcgc tgaaaggaaa atatcgatcc tcgcgccgat cggtacggcg
     2881 ttgttgggtt cccgggtggg ctcgacggtc gattggcccg tcccggcggg aagacgaacc
     2941 atgcgcatca aggacgttct gtaccaacct gaggccgcag gcgattacca cctgtaggta
     3001 tgtggtggtg aaggcatcag agttgctcat cccatagagt gtcactgaag aagagcggat
     3061 gttcgtcgtg cacgagacga ggcatgtcgc cgtacccttt tcaatcatgc gcccagcaca
     3121 gttcggaggt atcaatggac gtacgcagca aggtgtatac gtatcgaacc gcggttcagt
     3181 ggacggaaca aaagaaaggg acgatttcaa gtgaaggtaa gccggacatt caggtggcaa
     3241 caccgcctga attcaagggg catgcaggaa tctggtcacc ggaggatttg tatgtggcgg
     3301 cggcgaacat ctgcctcatg accacatttc tggctgttgc ggaacggggc ggcctggcgt
     3361 tcaccgcgta ccactgtgaa gcggaaggtc gtctggaact cgtggaggga aagtttcagg
     3421 tcacggtgat caccctgcgc ccacacatca cgctttcgcc aggaggggat gcttcgaaag
     3481 cgaaggaact gattgaaaag gcggaagcca attgcctgat ctccaactcg atgaagaccc
     3541 gtatcgcgtt ggagcccacg atcgtctgac gtgccggctg tggcatcttg cgccaggatc
     3601 aggtgtgggc tggggtgatt ctctccagtc caccgtgctg cgttcttccc cgcctctata
     3661 aacggtctct atccagagca ttgaccgaga tcctcgtgcc ggttcgattg gcacggggat
     3721 cgcatctact cctgtgtggc gcttgggtcc ttccgatggg gccgctcaaa aaggggcaca
     3781 ctatgcacct acgaatcgga gtgattgctg tctcgcagct gatcctcttg tcggcgattg
     3841 tggttgccgt gtatgcgggc cccgggaacg tcggcaaggg aaagacgctt tacgccaatc
     3901 tgtgcatccg ttgccatggt gtggacggaa aaggaaaggg cgagatgacc ttcacgccgc
     3961 cggtcgccga cctcaccgct cctgccgcgc aaaccaagtt ggatgccacg ctactaaaaa
     4021 cgattcatga tgggcgaagg gacacggcga tgggggcctg gaagtttgtc ctatcggaag
     4081 aagaaatgcg tgatgtgacg gcctatctgc ggcaattggg cagtgaggct ggccggggac
     4141 gtccctagaa atggaacctc tcatctgatg aattggcgca tctttggctg gggaattgcg
     4201 gcactgtgga tgatcacgat cggcatcatg tcgacgtttc tcgtgcaagg tcatacgaga
     4261 ccgggggatg acggccgcac agaaatcatc ctggcgccat ccgagcgaga tctggtgctg
     4321 gcggagatgc gtggcttgct caaggcgatc catggggtgg tcaccgtgct gggagcaggg
     4381 gatcaaccgt tgaaggcggc tgaaagctcc gcccgtgcgg ccggcatggc gatggcagcg
     4441 gacgtcaatc cggccatcat gttgaaactg cccctagcct ttaaacagat gggtatgtcg
     4501 attcacaaag atatggacca ccttgccgac gccattgcac aaggtgaatc tcaggtccac
     4561 attctcaatc gcctctcgag catcacagct cgctgcacca cctgccacga catgtatcgc
     4621 tttgggacac cataagccgc gacgaatcct ttttgcgcgg cgatactcta cttgaataga
     4681 agcgggtgaa cggttttgat acgcagtcga tgcttcaaac aagggaggcc atcatggcat
     4741 gcaatgtggg tggagttgag cgaccggtcc gaattgtgct gggcattctg ttgatcggca
     4801 tcggggtatt tggggcgctt ccgccggtgg gaatggggat cgccttggcg gcgggaacga
     4861 ttgcgctggt gacgggagcc ttagggttct gtccgctctg gagcctgttt ggcatcaaca
     4921 cctgttcggt cggagctggc aagaaagcct gatcggtgcc gaagatgggg cgggcgaggg
     4981 caagcgatgg tgagccatgc agaacagcct gatcagcagc cagaaggcgg attctccacg
     5041 ccggtcggtt cgcgacggac gttttttcag tgggttacgc tagccgcggc cgggctggtt
     5101 ggtgtcgggc tgtccattcc gttgctcagc acgctgatct cgccggcctt tcatcggcgc
     5161 cgtcgcgact gggttgatgt cggcgctgtg gatgacttgt cttccggtca ccccaagcaa
     5221 ttggaccatg tgaccacgat tcgggacggc tggttggaga cgacctcaca caaggcggtg
     5281 tgggcggtca agcaggcgca gggcgacatc aaagtgttct cgccgatctg cacgcatttg
     5341 gggtgcggct accgctggga cgaaacggac aaaaaatttc tctgtccctg tcatgggagt
     5401 tcgtatgacg tgaacggcca ggtattggga gggccagctc cgcggccact cgatacgctt
     5461 ccttcgaaag tcgaaggagg gcggcttctc gtcatgtaca aggacttcaa gtcgggtctg
     5521 ccgaccagtg tcgagatatg aacaactggt aagtggcgcc atcgacaggt ttacctcgcg
     5581 cctcacaact gggagttgaa tgccttctcg tttgtacgat tggctcgatg ctcgcctgaa
     5641 tctgaaaccg gttcagcgga cgttgctcga tgagccgata ccgggcggag cgagttggat
     5701 ttatgtcttc ggttcggtga cgctgttcct gttcgttctc caggccgcca cgggcatgtt
     5761 cctcgcgttg tattacgcgc ccaccccaga ccatgcctac gacagtgtcc gcttcatcga
     5821 aaccgacgtg actctcggct ggttggtgcg aggccttcac cattggggcg catcgtcgat
     5881 ggtcgtggcc atcgggcttc acatgctcca gacgtttctg tatggcgcgt ataaagcacc
     5941 gcgtgaagtg atgtggatgg taggggtggt cctgtttctc atcgtgatga ccttcgcctt
     6001 caccggttat cttctcccgt gggatcaaac ggcttactgg gcgacccaga tcgggatcaa
     6061 tatggtgggc accgttccgc tgatcggcga tgtagcctct cgcatcctgc gcggcgggga
     6121 gattctgggg gcgctgacgc tctcacgatt cttcgccatt catgtgctgt ttctgcccgc
     6181 gatgctcgtc acgggaattg cggtgcatct gttcgtcctg cggcgagtcg gacccgccgg
     6241 accctggacc gatgatcgag cctcactagg tgctgaaacc tttgctccgc ggcaggtgta
     6301 catggacgcc gtcgtcatcg ccggcgtgtt cctggttgtc gcggcattgg cattcagtat
     6361 tccgctgccc ctgaccgaca aggcgaaccc gtcggatacg agttttgtgc cggtgcctga
     6421 atggtacttt ctcttttatt atgaattgct caagtatgtg cacgggccgc tggaaccgtt
     6481 ggcgacctgg attctgccgc tctgtgtgat cctggtcatg ctgttctggc cgtttatcga
     6541 ccgcaatccg gtacgaaatc ctatccgtcg tccggtggcg ctcgggagcg gcctgctgtt
     6601 ccttctcgtc gtgttcggcc tgctaggcat ttcgatcagg aatctctatg cggtaccaag
     6661 ggtagatccg gctgtggcgc gggggcgtgc cgtctatgcg cagctcggtt gtgtcgggtg
     6721 ccatcggatt cacggcgaag gaggggcggt ggcgccggac ctgtcgacgg ttggagacac
     6781 gcggcctgat cgggagtggc acttgaagca tttccgggac cctcaatccg tatcgccggg
     6841 ctcgtttatg ccgaaattcc cgctcaccga tcagcagttg aatgacttga ccacgtatat
     6901 gctgagttta aaacgggcca cctgatgagg aaattcctca caaccagaag ggagagaatg
     6961 ggtatgcgaa tctggggcac gttgctgtgc actgtggggg tgctgctggg atcgatgccg
     7021 ataagtttgg ctgcgtccgg taaaggaaat ccggccacgg ggaaaaagct ctatcacgag
     7081 agttgccaga actgccatgg gcctgccgga aaaggcgata gcgagatggc agcctacctc
     7141 acgccggcac cggccgacct cacctccaaa accactcaag agaaaacgga tgcgcaattg
     7201 cgcaaggtga ttcaggaagg gcgtcccggc accgccatga ccgggtatgc cgcagccttc
     7261 gatgaagaaa aattgaatga cgtgatggcg tacattcgtt cgctcaagcc gtgagggaac
     7321 caggatgacg ccgatgcatg ctttcccgaa tccttttcct cacatctgtc cctaacctgc
     7381 atcttgaatg tgcgggctcc agagtgctgt agcacgatgc cgcaggcagc agaggaggac
     7441 tgtggctttt atcgccaagg ttatcaggga gcatcccgac gcatgcccgt caaaagccaa
     7501 ttctttttga cggcctcctg tcgacgtggt atgtagtttg cgagactctc tacgcatgcg
     7561 acatgttttg ttcagcgtca tcgtgatcgt cgggttgacg gcaggctgtg tcgagtcgaa
     7621 ggacacacgc ggagccgcac catcggccgt gagtcaatct gactctgcca ggctcgacgc
     7681 gctcttcagc catccctcgc ccgattccat tcccggtggg cagcgcgggg aacagattcg
     7741 cctcggatat gaactcgtcg tccatacgca acaattcgct gctccctacg tcggcaaccg
     7801 gctgacctgc gccaattgtc acttggatgc gggactcgat cccaattcgg cctccttcgt
     7861 ggggctgtcg cgggcctatc cggaataccg ggcccgggcg gggaaagttc tgacgctggc
     7921 cgaccgtatc aacgactgtt tcgagcgtaa tttgaacggg aaggcgattc cgcaagacag
     7981 tcacaagctt caagcgatcg tcgcgtacat cgaatggctg tcgaaggatg tgccggctgg
     8041 tagccgcatg gcctggcgcg gagttccgac tttgtcatcg accaagcctc ccgaccctgc
     8101 gaacggcgcg aaagtgttca ccgcgcgttg cgcattctgt cacggcgcgg atggacaagg
     8161 caccatggca gcccctccgg tctggggcgc gcagtcctac actatcggct cggatatggc
     8221 tcgtgtgtcg gtagccgcct cgttcatcaa acagaatatg ccacgtactc gagggtgggc
     8281 gctgtcggat caggaagcct acgacgtcgc agcttacatc aattcgcaac cgcgaccgga
     8341 tgtggcaggg aggggccgtg attggccgaa gggagagaag ccggcggatg cgcccaactg
     8401 aacgcgtacc atgccactgg tgataacggc cggtgaggaa cgcacgacca tgcggactgc
     8461 gggatgcgga cggaggagaa cagaatgaag ctcagcgtgg cgtaccaggg aggaacccgc
     8521 tacgacattc tcagcgaccg ccatcgcgtc gtaacggatc agcccaccga agacggcggt
     8581 accgatgcgg gcatgagccc ggtggagctg tttgtcggct ccgtcgcgag ctgcgtgggg
     8641 tattttgtcg gccaattctg cgcacggcac gacatctctc gtgaaggtct gaaggtggat
     8701 gccgaatggg ccgtggcgga agggccgcat cgtgtcggac agattcagtt ggcgattcgt
     8761 ctcccccacc gagtgacccc tgaacagaaa gagcggctgt tgagggtggc ccatgcgtgc
     8821 acggtacatc aatcgatcat ggtcccggtt caggtagcga ttgagttgaa tcctcatacg
     8881 tagaaggtga ggtgggcatg aggaaagggc gaatatggca gtgacgaggc gggcgttgtt
     8941 cgaacgggtg ctgcagggcc tcggcgcggc tgtggtcgcg ggcggcgtcg atagagcgtt
     9001 cgccgacagt cagagcgacg tcatcgggca ggtgagcggc ccgctcacgg ttcgggtctc
     9061 ccggccgttc gatgcggaaa cacccgtgcg ggaatttggg tcctggctca caccgaacga
     9121 acgatttttt gtgcgcagtc acttcgggcc acccggtgcg gagacaattc aaccggaggc
     9181 atggcggctg acggtaaaag gactcgtaca gaatgagttg accctgaccc tgtccgaact
     9241 cagaaagttc gagcaagtta ccattaccgc cgtgctgcaa tgcagtggca acggtcgtgc
     9301 gcaccatcgc cccaaggttc ccggcgtgca atgggaacgg ggcgcagcgg gaaacgcgca
     9361 atggaccggt atgcggctgc gcgacctctt acagcgtgcc ggggtaaagc cgcagggcct
     9421 ccatgtgcaa atgcaaggag ccgatcgtcc ggctctgcct accgtgcctc tcttcacgcg
     9481 aagcattccc atcgccaaag cgtttcatcc ggacacgctc ctcgcctatg agatgaatgg
     9541 tcggccgtta ccgcttctgc atggcgcacc gctgcgggtg attacgccgg gctggatggc
     9601 cgagtcctgc atgaaatggt taacggagct caccctgcgt gcggacgaaa cacccggata
     9661 ttacatgcag caggcctatc gtattccgga gacgtcgatc cagccggggt ccggtttgcc
     9721 gggaagcgtg atggtgccgg tcgagcagat gcccgtgaag tcgctcattg ccgcgcccgg
     9781 cgaaggggac acgctgaaag ccggtccggt gaccattcaa ggggtggcct gggcgggtga
     9841 atcgccgatc accaaggtgg aagtatcttg cgacgacgga aagacctggg aaccggctcg
     9901 tttgctgggt gaagcacaac cctatgcctg gcggcaatgg caatacttgt ggaatgcgcg
     9961 tcaggtgggg ccaaccacga tcctctgccg ggcgacggat gcgcaggggg ctcagcaacc
    10021 agagaagagc ccctggaatc caggggggtt tttgtggaat gggtgggatc gcctggctgt
    10081 gacggtggcg gcatgagggg cgtgatggag ggggcgcaaa gggagcgagg gcgatggtct
    10141 ttgttggctg cgggactggt actgctcctc ggcattgctg ccgggacggc ggcgcaagag
    10201 gatgacaagc atacgattga accggcgcag gctcgccggg cggtgacgtt aattcatgcc
    10261 cgttgcgccg tgtgccacac gaccgatctg atcgtgcaac agaggctacc gccggatcga
    10321 tggcagatca cggtggagaa gatgatgcat tggggcgcgg acttgtctaa ggacgaagcc
    10381 gcggcccttc ttcagtttgt gacggcccgc taccaccccg gtgcgccgga ccacttgccg
    10441 tcgatcgaag aagaattggc gctgaccgct ccggctggag ggcccagcac cgcgagtgac
    10501 ggcccgcttg tcggggtgcc ggcccgaggc gcggaaatct ttgcgcggaa ctgccaggcg
    10561 tgccatggcg agggggcgat gggaggcgcg ggacccaaac tggcccgcaa taaaatcttg
    10621 aaaaatgagg gagtcttctg ggagacggtg ctccatggcc ggggcccgat gccggcctgg
    10681 ggctcggtct tgagtcatca ggaggtcgca gatatccatg cctggttggc atcacgctga
    10741 ccgggtgcgc agtgaggtga acgaaagggg tgtttcatgg gtggaagacg gacggcgatg
    10801 atcgggtgcg cgttggtcat attggtggga ctgttttcat tcccccgcct gctcttgggc
    10861 agtgatcaga ctcgcgtcaa ggagatgatc cagaataact gtgccggatg tcaccgcctg
    10921 gaagggaaag cggagtcgcg gttcaacttg aaggcacccg atctgatttg ggccgg
//
LOCUS       DAOQPD010000104         9752 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_3706_length_9752_cov_25.860266, whole genome shotgun sequence.
ACCESSION   DAOQPD010000104 DAOQPD010000000
VERSION     DAOQPD010000104.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 9752)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 9752)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9752
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3706_length_9752_cov_25.860266"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(2..1024)
                     /locus_tag="PK063_17015"
     CDS             complement(2..1024)
                     /locus_tag="PK063_17015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase"
                     /protein_id="HMZ98805.1"
                     /translation="MGSVKGLVLVTGAAGFIGSHVAKRLLDRGDSVLGLDNLNDYYDV
                     RLKEARLARLQTHPQFQFVKLDVSDRPGMAALFQQHSIRRVVHLAAQAGVRYSLVNPH
                     AYTAANIEGFLNILEGCRHHKVEHLVYASTSSVYGGHTKMPFSVHDNVDHPVSLYAAT
                     KKANELMAHCYAHLYRFPITGLRFFTVYGPWGRPDMALFLFTKAILEGKPIDVFNYGK
                     MQRDFTYVDDIAEGVLRTLDRPAQVDPQWSSDQPDPGSSSAPYRLYNIGNNQPVDLLH
                     FIEVLEQTLGKKAEKNLLPLQAGDVPATYADVADLMRDTGFKPATSIETGIARFVEWY
                     REYYKV"
     gene            complement(1048..2667)
                     /locus_tag="PK063_17020"
     CDS             complement(1048..2667)
                     /locus_tag="PK063_17020"
                     /inference="COORDINATES: protein motif:HMM:NF024874.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HMZ98806.1"
                     /translation="MGIWDTLPRDQYVGLAPWVWVQLESNQPPGPFPFIGGVAPEVVA
                     SLHEAHSLFLACVETAISDVFSRRATLGDPQTRVRLEDAYAELVNSRQQLSQHITARR
                     QADGQFHWSHPFDATKSATVVNTGLRIFNAVKRQAIPVPFERPMGPIVGRLLGMLDGT
                     QQAGAIQTIVATAGREGERLLTKVMELLVQYECLTPAKNTSIRSQWLSQTKDRDTIHL
                     GHAALMYRRRDQFLLFDPWLLPWFAESNVPSLWVSLLPKPAAIFLTHDHDDHVDPRTL
                     LHVPKDVPIVIPSRRNRKKYFYDYLPLLRELGFSHIIELAHGETWNFEGGAVVSVPFY
                     GEDPCDLEMPRNCYLVTDRGQNVLVHADSGPTNSGRSAIKEGVIQQLVQKYGPISLVL
                     ASQQQLQEIRSYAAHAPLSHPGLWLEVGENGYLTNSYLNELCATAQARLFVSYATGGA
                     DWYPDHLSFMFSERNPARTALLTANWEQPEKLKDLLSSHDCRYHRARALDLFRTGDDG
                     MVQVSSGVEALSPMPLYRLDHGEPAFMRRGR"
     gene            complement(2673..3104)
                     /locus_tag="PK063_17025"
     CDS             complement(2673..3104)
                     /locus_tag="PK063_17025"
                     /inference="COORDINATES: protein motif:HMM:NF013098.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HMZ98807.1"
                     /translation="MPTHRGLRHLALRVTDLARSRAFYERFLAMKVVWEPDPDNVYFS
                     SGSDNLALHQIAPAELAQYQPLRGQLLDHVGVIMENPAQVDDLFRDVQQDGARYGATI
                     AKPPKQHRDGSYSFYFADPDGNVIQALYEPTISRMEFRPPA"
     gene            3276..4115
                     /locus_tag="PK063_17030"
     CDS             3276..4115
                     /locus_tag="PK063_17030"
                     /inference="COORDINATES: protein motif:HMM:NF015722.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
                     /protein_id="HMZ98808.1"
                     /translation="MLARSVLALVVALIGLNGTGANAFAAEHTSPPKEITGKDGAPMV
                     LIPAGSYPMGVPTGDRDGGRDEYPRHVIEIDPFYIDKYEVTNARYLEFVKATNHRVPQ
                     NPKNPTRNLWEGIGIPASLADRPVINVDWSDADAYCTWAGRRLPREAEWEKAAKGNND
                     WRFPWGNVEPTDGHLNFNQKWVGEKTLMPVGSYEKGKSPYGVYDMAGNVWEWVNDWYD
                     PKYYEKSPGKNPPGPESGTKKVIRGAGWQNETPTVRIFTRVDSDPTIRNESTGFRCAA
                     DAK"
     gene            4145..4987
                     /locus_tag="PK063_17035"
     CDS             4145..4987
                     /locus_tag="PK063_17035"
                     /EC_number="4.2.1.75"
                     /inference="COORDINATES: protein motif:HMM:NF014641.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004852 - uroporphyrinogen-III synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006780 - uroporphyrinogen III biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006782 - protoporphyrinogen IX
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="HMZ98809.1"
                     /translation="MATAGFNGLKVVSFESRMATEMTRLIERHGGKPLVAPALREIPL
                     ADNSAALQFGEKLLREGLDVLVLMTGAGTTALFEVLETRHTKSELAAALKHTVLIARG
                     PKPVAALKSLGFQPTLTVPEPNTWMDVVSTLDAHRPVNGLRVAVQEYGVSNRDLLEAL
                     KQRGAQITPVPIYRWALPEDTAPMKEALRQILAGQVQVVLITNAAQFDHLIQLAEQEG
                     ETAMFKQACGRLVLASIGPTASERIRSHGLTVDFEPSHGKMGILVKETSEQALRLLAT
                     KRAS"
     gene            complement(5046..5966)
                     /locus_tag="PK063_17040"
     CDS             complement(5046..5966)
                     /locus_tag="PK063_17040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
                     /protein_id="HMZ98810.1"
                     /translation="MRGIAMWAASAAVLAMSGTLYALDVADVVREWTPEGKKLAAERV
                     KLPAHDEMIRIPAGGFLMGSDRKVDKNSYLAEFPQRKVYLDAYDIDKYEVTTVQFLKY
                     VLAHNLDPLIDWQYDGGNFQDTMVSHPVMHVSWFDAEAYCKWVGKRLPTEAEWEKAAR
                     GEDGRIYPWGNQMAGLSRANFGRTGLSGPVRDRPERLLLYPPIISVDKYDNAISPYGV
                     FQMAGNVAEWVNDWYDPKYYASAPDKNPKGPETGSQRSFRGGGWIDSTPSVRVAQRNG
                     TDPNTKMNWMGFRCARDAKEGVAGSTTEAK"
     gene            complement(6001..6684)
                     /locus_tag="PK063_17045"
     CDS             complement(6001..6684)
                     /locus_tag="PK063_17045"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98811.1"
                     /translation="MREGDAEGMTMCIKQTGKFDRVIGKIRRMCLWKLAGSALALTAT
                     IGIMDAAALEFTADQITKINGRTQKSNIFYRDNMWRIEHHTMGPVNISIVRKDKQVVW
                     LLLSRMKHFKTVPYKAEQDLKVSEHLEGEISREEIGTETREGHPTTLYEVTVKEGERT
                     EVYYQWLATDIHFPMKLAKKDGSWIVEYQHVKFRPLIDYLFQLPLNFEPLEEFDHQPA
                     AAEPNHQPM"
     gene            complement(6942..7553)
                     /locus_tag="PK063_17050"
     CDS             complement(6942..7553)
                     /locus_tag="PK063_17050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YceI family protein"
                     /protein_id="HMZ98812.1"
                     /translation="MTKRTGRALAMWCLGTGMLLSATFAQAEMARYDVDLDHSIVEFK
                     VAHMVVSKTTGHFKDYTGFIEMDPDAGTVKALEATIKTASVTTNHEKRDAHLRNPDFF
                     DAEKYPTITYTMKSYKKAGDGYVAVGDITLHGVTKEITLTGNFNGVAKDPWGNTRAGF
                     TAEGKLNRKDFGMVWNKALDSGGLVVGDDVFIRLDIECIKAKS"
     gene            complement(7556..8581)
                     /locus_tag="PK063_17055"
     CDS             complement(7556..8581)
                     /locus_tag="PK063_17055"
                     /inference="COORDINATES: protein motif:HMM:NF024503.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015291 - secondary active transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB family protein"
                     /protein_id="HMZ98813.1"
                     /translation="MQHQLHSTCAGLILGLGVMFCVSVPLSATAGPSANQAPAAPKRW
                     AQFDLVSTEPDGSVQAGKDVVLSITLGGVPAGTESVMAMIESNGFQSQTVSLSEEPTA
                     SVYQGTVILEPNSTLKSRTTVHPKAVRVRVSFARAKVTGLEEFLKRDVYVTIGEPPAN
                     ETETEVQPGPVAESPEADAAAVQKATEQAMAVNATIAEEDLLPLPPPGESKAYWKQVS
                     DLISRNWSRQIRSIRRAPSSETVRVQFKMYASGIAQVIQLEKSSGARDVNDAGLQTII
                     HAQPFPPIPPDLGSDVVDVHVRMRTGAKVATRDVEMTVDKKPSKTAPPSAPTPKEGAA
                     ASGSTKE"
     gene            8734..>9752
                     /gene="tdh"
                     /locus_tag="PK063_17060"
     CDS             8734..>9752
                     /gene="tdh"
                     /locus_tag="PK063_17060"
                     /EC_number="1.1.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008743 - L-threonine 3-dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006567 - threonine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HMZ98814.1"
                     /translation="MRALVKTAAQPGLTYTERPDPSPGPNDAVIRVKATSLCGTDAHI
                     YNWDAWAHSRIHPPRIIGHEMCGEVVAVGSDVSLVTVGDYVAAESHLTCGACFQCRTG
                     QAHVCKNYRILGVDLDGSFADYIVLPETVLWKTSPDIPPELASLQEPLGNAVDAALVE
                     DLTGHTVLITGCGPTGLFAAAVARTAGAATIIATDVSDYRLGLAKQVGVDHVLNAKTD
                     GPEAIAAAILDITKGEGVDASLEMSGHPTALHHAFRSVKNGGRVTLFGIPTGPVTCDL
                     ANEVIFKGIRVHGITGRRLFSTWYRLAGLFKAGLNIRPVLTHTFPLKDFAQGFELIKS
                     GQCGKV"
BASE COUNT         2036 a         2928 c         2730 g         2058 t
ORIGIN      
        1 ctcagacctt gtagtactcg cggtaccact ccacgaatcg agcgatgccg gtttcaatcg
       61 aggtggccgg cttgaagcct gtgtcccgca tgagatctgc cacatcggca taggtcgccg
      121 gcacatcgcc ggcctggagc ggcaggagat ttttttcagc cttcttgccg agcgtctgct
      181 cgagcacctc gataaaatgc agaaggtcga ccggctgatt attgccgata ttgtagagtc
      241 gatagggtgc agaactgcta ccgggatcag gctgatcgct cgaccactgt ggatcaacct
      301 gcgcgggccg gtcgagcgtg cgcaacacgc cttcggcgat atcgtcgaca taggtgaaat
      361 cgcgctgcat ctttccgtaa ttgaagacgt cgatcggttt gccttcgaga atcgccttgg
      421 tgaacaaaaa cagcgccata tcgggacggc cccaaggccc gtagactgtg aagaaccgca
      481 atccggtgat gggaaatcga tacagatgcg cataacaatg cgccatcaac tcgttggctt
      541 ttttggtggc ggcatacagc gacacaggat gatcgacatt gtcatgcacc gaaaacggca
      601 tcttggtatg gccaccgtag actgaactcg tggaggcata gaccagatgc tcgaccttgt
      661 gatgccggca gccttccaga atgttcagaa atccctcgat attcgcggcc gtataggcat
      721 ggggattcac gagcgagtag cggacgccgg cctgcgccgc cagatgcacc acgcgacgaa
      781 tcgagtgctg ttggaagagg gccgccatgc cgggacggtc tgacacatcc agctttacga
      841 attgaaactg aggatgcgtc tgcagccgag ccaggcgggc ttctttcaaa cgaacgtcgt
      901 aataatcgtt caggttgtcc aaccccagaa cggaatcccc gcgatccagc aatcgcttgg
      961 ccacatgcga cccgatgaat cccgcagcgc cggtgacgag caccaatccc tttacagacc
     1021 ccataacgac gcgtcccttc tgatcaatta tcttccccgc ctcatgaatg ccggttcgcc
     1081 atgatcgagg cgatagagcg gcatcggcga caaggcctcc actccggacg agacctggac
     1141 catgccatca tcacccgtgc ggaacagatc caacgcccga gcgcgatgat accggcaatc
     1201 atgtgacgac agaagatctt ttagtttttc cggctgctcc caattggccg tgagcaatgc
     1261 ggtgcgcgcg ggattgcgct cactgaacat gaaggacaga tggtccggat accaatcggc
     1321 cccgccggtg gcataggaca caaacagccg tgcctgcgca gtggcgcata actcattcag
     1381 gtaactattt gtaagatagc cgttctcacc cacctcgagc cagagtccgg gatgagacaa
     1441 tggcgcatgg gcggcataac tgcggatctc ctgcaattgt tgttgggaag ccagcacaag
     1501 ggagatcgga ccatatttct gaacgagctg ctgaatcacg ccttctttaa tggccgaccg
     1561 cccgctgttt gtcggaccgc tgtcggcatg caccagcacg ttctgcccgc gatcggtcac
     1621 gagataacag tttcgaggca tctccaaatc gcacggatct tcgccgtaaa agggaaccga
     1681 gacgacggca ccgccttcaa agttccaggt ctcgccgtga gccagttcga tgatatggct
     1741 gaaccccagt tcccgaagca atggcaggta gtcgtaaaaa tacttcttgc gattccgccg
     1801 gctgggaatg acgatcggga catccttcgg cacatgcagc agcgtcctgg gatcgacgtg
     1861 gtcatcgtgg tcatgtgtca aaaaaattgc cgccggcttc gggagcaaag atacccacaa
     1921 actcggcaca ttggattccg caaaccaggg gagcagccag ggatcgaaca gcagaaactg
     1981 gtcgcgccgc cgatacatga gcgcggcatg cccgagatga attgtgtccc ggtccttggt
     2041 ttgggagagc cactgggatc ggattgaggt gttcttggca ggcgtgaggc attcgtattg
     2101 gacgagcaac tccatcacct tggtcaacag ccgctcgccc tcccgtcccg ccgtcgcgac
     2161 gatcgtctga atggcgccgg cctgctgtgt gccatccaac attcccagca gtcttccgac
     2221 gatcggtccc atgggacgct cgaacggcac gggaatcgcc tggcgcttca cggcattgaa
     2281 gatacgcagg ccggtattga cgacggtggc ggatttcgtc gcatcgaacg gatgcgacca
     2341 atgaaactgc ccatcggcct ggcgacgcgc cgtgatgtgc tggctcagtt gttggcggga
     2401 attgacgagc tccgcataag cgtcttccaa ccgcactctg gtctgtggat caccgagcgt
     2461 cgcgcggcgg gagaacacat cgctgatggc ggtttccacg caggccagga agaggctgtg
     2521 ggcttcgtgc aaactcgcca cgacctccgg agcgaccccg ccgataaagg gaaacggtcc
     2581 cggcggctgg ttactctcaa gctgcaccca cacccaggga gccagcccga catactgatc
     2641 acgcggcaat gtatcccaaa tacccatact cgtcaggcgg gaggccggaa ctccatgcgg
     2701 ctgatagtcg gttcatataa ggcctggatg acattgccat ccggatcggc aaaatagaag
     2761 gagtagctgc catcgcgatg ttgcttcggc ggcttcgcga tggtggcccc atagcgtgcc
     2821 ccgtcctgtt gcacgtcccg gaacagatca tccacctgcg ccggattctc catgatcaca
     2881 ccgacatggt cgagcagttg tccacgcaat ggctggtatt gcgccaactc agcaggggcg
     2941 atttgatgca gggccaggtt gtcggatccc gagctgaaat acacattgtc gggatctggt
     3001 tcccatacga ccttcatggc cagaaaccgc tcatagaacg cacgggaccg agccaggtcg
     3061 gtgacacgca gggccagatg tcgtaagcct cgatgggttg gcacgccggg atctcctcgg
     3121 gcgtatagta ggtggggggc tgtcaccccg tcaatcctca ttcttttgcc acgaacgtca
     3181 ttcaccccat ctttcctcca ccagtcatgt ttgaaaaatc cggagctgtg gtacgatcgg
     3241 tcatcgattc tctcgaacca aaggagcttg cagctatgtt ggcacgatcc gtcctggcat
     3301 tagtggtagc gcttatcgga ttgaatggca cgggggctaa tgcattcgcc gcggaacaca
     3361 cctccccgcc caaagaaatc acgggaaaag acggagcgcc gatggtcttg atcccggcag
     3421 ggtcctatcc catgggggtg ccgaccggcg accgtgacgg cggacgcgat gaatatccgc
     3481 gccatgtcat cgagatcgat ccgttttaca tcgataagta tgaggtcacg aacgcgcggt
     3541 atctggaatt cgtcaaggcc acgaatcatc gcgttcccca aaaccccaag aatcccacac
     3601 ggaatctctg ggaagggatc ggcattcctg catcgctggc tgaccgtccc gtgatcaatg
     3661 ttgattggtc cgatgccgac gcctactgca catgggccgg ccgacggctg ccgcgcgaag
     3721 cggagtggga aaaagccgcc aaggggaaca acgattggcg ctttccatgg ggtaacgtgg
     3781 agccgactga cggacatttg aatttcaacc agaagtgggt cggcgaaaag accttgatgc
     3841 ccgtgggtag ttacgagaag ggcaaaagtc cttacggcgt ctatgacatg gcaggcaacg
     3901 tctgggaatg ggtcaatgac tggtacgatc cgaagtacta tgagaagagt cccggcaaga
     3961 atcctcccgg gccggaaagt ggcacgaaaa aagtcattcg cggtgccggc tggcagaacg
     4021 agacgccaac cgtccggatc ttcacccggg tggatagcga cccgacgatt cgcaacgaat
     4081 caacagggtt tcgctgcgcg gcagacgcca agtagcagag tcggcgggca aggcagggag
     4141 ggcgatggcc acggctggat ttaacgggtt aaaggtcgtc tcatttgagt cgcgtatggc
     4201 gacggaaatg acgcgcctca tcgagcgcca tggcggcaag ccgctcgtgg cgccggcgtt
     4261 gcgggaaatt ccgctggcgg acaattcggc ggcactacaa ttcggcgaga agctactgcg
     4321 tgaagggctg gacgtgctgg tgctgatgac cggcgccggc acgacggctc tctttgaggt
     4381 tctcgagact cgccacacca aaagcgaact cgccgcagca ttgaagcaca ccgtgctgat
     4441 cgcccgtggg cccaaaccgg tggccgcgct gaagtcgctg gggttccaac ccaccttaac
     4501 cgtcccggag cctaatacct ggatggatgt cgtctcgacg ctggacgcgc atcgaccggt
     4561 gaacggattg cgcgtggcgg tacaggaata tggcgtatcg aaccgtgact tattagaggc
     4621 cctgaagcaa cggggagcac aaatcactcc ggtgcccatc tatcggtggg cactgccgga
     4681 agacaccgcg ccgatgaagg aagccttacg tcagattctg gcgggacaag tccaggtggt
     4741 gttgatcacc aatgccgcgc agtttgatca cctgatacag ctggcagaac aggagggtga
     4801 aaccgcaatg ttcaagcaag cctgcggaag attggtgctc gcctccatcg gccctactgc
     4861 cagcgagcgc atccgcagcc atgggctcac agtcgatttc gaaccctcgc acgggaaaat
     4921 gggtattctc gtgaaagaaa ccagcgagca ggctctgcgt cttttggcta cgaagcgagc
     4981 ctcctgaaca cgcccgcctg ccaatcaggc atcattccga cacctgctgg acatcccatc
     5041 ggcaattatt tggcctcggt cgtcgatcct gctacccctt ccttggcatc tcgcgcacaa
     5101 cggaatccca tccagttcat cttggtattc ggatccgtcc cattacgctg ggcgacgcgc
     5161 acgctaggtg tgctatcgat ccagcctccg ccgcgaaagc ttcgctggct gccggtttca
     5221 gggcccttgg gatttttgtc cggggcactg gcatagtatt tcgggtcgta ccaatcattg
     5281 acccattccg ccacgttacc cgccatctga aacacgccat aggggctgat cgcattgtca
     5341 tacttatcaa ccgagatgat cggtggatag agcaacagcc gttccggacg atcccgcacc
     5401 ggcccggaca acccggtccg gccgaagttc gcccgcgaga gtcccgccat ttgattgccc
     5461 cagggataaa tgcgcccgtc ctcaccgcgg gcggcctttt cccactcggc ttcggtcggc
     5521 aatcgtttgc ctacccattt gcaataggcc tcggcatcga accaggagac atgcatcacc
     5581 ggatggctga ccatggtgtc ttgaaaattc ccgccgtcgt actgccaatc gatcagcggg
     5641 tcgagattgt gggccagcac atatttgaga aactgcacgg tcgtcacttc gtatttgtcg
     5701 atatcgtagg catccaaata gactttccgt tgcggaaatt cggccaggta ggaattcttg
     5761 tcgaccttgc ggtcgcttcc cataagaaac ccgccggctg gaatacgaat catctcatcg
     5821 tgtgccggca acttcacgcg ttccgctgcc agctttttcc cttccggcgt ccattccctg
     5881 acgacatcgg cgacatcgag cgcataaaga gtcccgctca ttgccaacac ggccgcgctc
     5941 gcggcccaca tggctattcc tcgcatacgc acgattttgc tcctttatcc gttgatcatc
     6001 ctacatcggc tggtgattcg gctccgcagc agccggctgg tgatcaaatt cttccaatgg
     6061 ttcgaagttg agcggtaact gaaacagata atcgattaat ggccggaatt tgacgtgctg
     6121 atactcgacg atccagctcc cgtctttttt ggccagcttc atggggaagt ggatatcggt
     6181 ggcaagccac tggtaataca cttctgtccg ttcgccttcc ttgaccgtca cttcatacag
     6241 cgtcgtcgga tgcccttcgc gcgtttccgt tccaatttct tcacgcgaga tttcaccttc
     6301 cagatgctcg gacaccttga gatcctgctc cgccttatag ggcacggttt tgaaatgctt
     6361 catacgcgac agcagcagcc agacgacctg cttgtcttta cgcacgatgc tgatgttgac
     6421 cggccccatc gtgtgatgct cgatccgcca catgttgtcg cgatagaaga tattggattt
     6481 ctgggtccgg ccattgatct tggtgatctg atcggccgta aactctaacg ccgcggcatc
     6541 catgatgccg atcgttgctg tcagcgccag cgctgaccct gccagtttcc acaagcacat
     6601 gcggcgaatc ttaccgatga cgcgatcgaa ttttccagtc tgcttgatac acatcgtcat
     6661 accctctgcg tccccttcac gcactccgtc ctcctccgtc ctcccccgtc cgtccaagcc
     6721 ctgcgcgttg aaaccggcac accaagaatc gacagcgaac aagatgtcca ggacatcctc
     6781 gctccactat gaccagctgc tgtgtctgct gaaaccggcg tcacgagatg ggaacgggtt
     6841 gcatccccag aagggatact ccgccagatg cgcggttgct ggctcagcct gcccggcaca
     6901 gaaccgggca ggcgcgtggc ccctgagaga ggccgtgtgg cttacgattt cgccttaata
     6961 cattcgatgt ccaatctgat aaaaacgtcg tctccgacga ccaggccgcc gctatcgagc
     7021 gccttgttcc acaccatccc gaaatccttc cgattcagtt tgccttcggc cgtaaacccg
     7081 gcgcgcgtgt tcccccacgg atccttcgcg acaccattga aattccccgt cagtgtgatc
     7141 tccttggtca caccgtgcag ggtgatatcg ccgaccgcca catatccgtc gccggccttt
     7201 ttataacttt tcatggtgta ggtgatagtc gggtactttt cagcatcaaa gaagtcgggg
     7261 ttgcgtaaat gcgcgtcgcg tttttcgtga ttggtcgtca ccgacgcggt cttgatcgtg
     7321 gcttcaagcg ccttgaccgt tccggcatcg ggatccattt cgatgaagcc ggtgtagtcc
     7381 ttgaaatgcc cggtcgtctt cgacaccacc atgtgggcaa ccttgaactc cacgattgag
     7441 tggtcgagat ccacgtcata ccgtgccatt tctgcttgcg cgaaggttgc actcagcagc
     7501 attcccgttc ccagacacca catggctagc gcacgaccgg tccgtttcgt catagttact
     7561 cctttgtaga accgcttgcc gcggctcctt ctttgggtgt tggggcggag ggtggagcag
     7621 ttttggacgg ctttttatca accgtcattt ccacatcgcg cgtggcgact ttcgcccccg
     7681 ttcgcatacg cacatgcaca tcgacgacat cgctgccgag atcgggggga atcggtggaa
     7741 acggctgggc atggatgatg gtctgaagcc cggcatcgtt cacgtcacga gccccggaac
     7801 ttttctccaa ttgaatcact tgggcaatcc cgctcgcata cattttgaac tgcacacgaa
     7861 cggtttcact gctgggcgcg cgacgaatag aacggatttg ccggctccaa ttccggctga
     7921 tcagatcact cacctgcttc caataggctt tcgattcgcc gggaggagga agcggcagca
     7981 gatcttcttc ggcgatcgtc gcgttaacgg ccatcgcctg ctccgtcgcc ttttgcacgg
     8041 ccgccgcatc ggcttccgga ctttcggcca ccggtccagg ttggacctca gtctcggttt
     8101 cgttggcggg cggctctccg atcgtcacat agacgtctcg tttcagaaac tcttccagcc
     8161 cggtgacctt cgcgcgggcg aacgacaccc ggactcgcac ggctttcgga tgcaccgtgg
     8221 tgcgactctt caacgtggaa ttgggttcca gaatcaccgt gccttgatac accgaagccg
     8281 tcggctcctc actcaaggac accgtctggc tttgaaatcc gttggactcg atcatggcca
     8341 tgacggattc cgttccggcc ggtacgccac ccaacgtgat gctcaacacc acatctttgc
     8401 cggcctgcac cgacccatcc ggttcggtac tgaccagatc aaattgggcc cagcgtttcg
     8461 gggcggccgg agcctgatta gcggacggac cggccgtggc tgaaagtggc acacttacgc
     8521 agaacatcac tcccagtcca aggatgagac ccgcgcaggt ggaatgtagc tggtgctgca
     8581 tgctcgcatc ctacccaggc gccctaccca gttcaacccg ttttttgggc gccctcggct
     8641 acgagctgat ccggggcatg atccgccgac gggagatccc gacgggtttc tgcttcggct
     8701 aggcatttct tatggtcttg ctataatgag cccatgcgtg cgcttgtgaa aactgccgcc
     8761 cagccgggcc tgacctacac cgaacgtccc gatcccagcc cagggcctaa cgacgcggtg
     8821 atccgggtca aagcaacatc gctctgcgga accgatgccc acatctacaa ctgggatgcc
     8881 tgggcccaca gtcggatcca tcctccacga atcatcggcc acgaaatgtg cggcgaggtc
     8941 gtcgcagtcg ggtcggatgt gagcctggtg acggtgggtg actatgtcgc ggccgaatca
     9001 cacttgacct gtggcgcctg ctttcaatgc cgtaccggac aagcgcatgt ctgcaagaat
     9061 taccgcatcc tcggcgtcga tctggatgga tcgtttgccg actacatcgt cttgccggag
     9121 actgtcctct ggaaaacatc gccggacatt cccccggaac tggcctcttt acaggaaccc
     9181 ttgggcaatg cggtcgatgc ggcgctggtc gaagacctca ccggacacac cgtcttaatt
     9241 accggttgcg ggccgaccgg cctctttgcc gccgccgtcg cccgcacagc aggcgccgcc
     9301 accattatcg ccaccgatgt cagtgactac cgtcttggat tagcaaaaca ggtaggggtc
     9361 gaccacgtgc tgaacgcgaa aaccgacgga ccggaggcca ttgccgcggc tattctcgac
     9421 atcaccaagg gagaaggcgt cgatgcctcg ctggagatgt cggggcaccc caccgcgttg
     9481 caccatgcct ttcgttccgt aaaaaacggc ggccgcgtca cgctgttcgg cattcccacc
     9541 ggtcccgtga cctgcgatct cgccaatgaa gtgatattca aaggcattcg tgtccacggc
     9601 atcaccggcc ggcggctgtt cagcacctgg tatcggctgg cgggactgtt caaggccggg
     9661 ctcaacatcc ggccggtttt gacccatacc tttccgctga aagactttgc ccaaggattt
     9721 gaattgatca agtccggcca atgcggcaaa gt
//
LOCUS       DAOQPD010000105         9346 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_3952_length_9346_cov_23.449575, whole genome shotgun sequence.
ACCESSION   DAOQPD010000105 DAOQPD010000000
VERSION     DAOQPD010000105.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 9346)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 9346)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9346
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3952_length_9346_cov_23.449575"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..599)
                     /locus_tag="PK063_17065"
     CDS             complement(<1..599)
                     /locus_tag="PK063_17065"
                     /inference="COORDINATES: protein motif:HMM:NF026042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HMZ98815.1"
                     /translation="MGDPKGFLKYAREGPKRKPIELRVLDWKEMYEPIPEEKLKVQGA
                     RCMDCGVPFCQGNTGCPVVNLIPEWNDLVYRGRWKDALKALHTTNNFPEFTGRLCPAP
                     CEGACVLGINSDPVSIRVLEWNIIDRGFNEGLVEPALPVRKTGKTVAIIGSGPAGLAA
                     AQQLARAGHSVTVFEKADRIGGLLRYGIPDFKMEKWVIDR"
     gene            complement(679..5199)
                     /gene="gltB"
                     /locus_tag="PK063_17070"
     CDS             complement(679..5199)
                     /gene="gltB"
                     /locus_tag="PK063_17070"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0015930 - glutamate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006807 - nitrogen compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase large subunit"
                     /protein_id="HMZ98816.1"
                     /translation="MNVPGLPPKQGLYDPQHEKDSCGVGFVVDIKGQRSHQIVQQGLQ
                     VLESLTHRGAQGCDPCTGDGAGILLQVPHEFFKRAAKDSGIKLPGAGEYGVGMVFLPP
                     DADARAQCETVFTRVIKDAGAKLLGWRDVPVKSDAIGPVARSTEPFMRQVFIARGIFT
                     DEEFERRLYVIRKCAERAVRESAIEGRDYFYIPSLSSSTIVFKGLLLPHQIPQYYQDL
                     TDSSLTSAMALVHSRFSTNTFPTWPLAHPYRYICHNGEINTLKGNVNWMRARQGRLNS
                     ELFGEDMKKLFPIVYENQSDSASLDNALEFLVLGGRSLPHAMMMLIPEPWVANPQMDL
                     DRRGFYEYHAAMQEPWDGPAAVCFTDGKLIGATLDRNGLRPCRYQVTTDGLVVLASEA
                     GVLPMDPQRIRQKGRLMPGRMFLVDTEQGRIIDDEEVKADIVRRKPYRSWVTEHRISL
                     DELPDPINVPQPDHPTIRQRQQAFGYTIEELKMVITPMVVEGQEAISSMGTDTPLAVL
                     SERPQLLFKYFKQLFAQVTNPPIDPIREELVMSLTTSIGPKPNLMDEHPESARRIRVK
                     QPILTNADLHKIREIADPHFKSKTLKMLFRVAEGPEGLGAAVDDLCRQASQAIREGYK
                     FLILSDRGVNAEWAPIPSLLGVAAVHHHLVRECTRTEVGLTVETGEPRDVHHFACLIG
                     FGAGTVNPYLVFESLVDLERDGYFPEGLDAATAEGKFIKAINKGLLKIFSKMGISTVQ
                     SYCGAQIFEAIGLNHELIDRYFTGTPSRIEGIGIREIGEETLRRHRVAYEPVPIRQLD
                     FGGEIHYRIQGEHHNWNPDTIYKLQHATRNNDPKTFAEFSQLVNDESKRRSNLRGLLE
                     FKFLPEPIALNEVEPAKDIVKRFTTGAMSFGSISKEAHETLAIAMNRLGAKSNTGEGG
                     EDPERFEPLPNGDSRNSYIKQVASARFGVTSHYLVNAKELQIKMAQGAKPGEGGQLPG
                     HKVDENIARLRYSTPGVQLISPPPHHDIYSIEDLAQLIFDLKNANADAAVSVKLVSEV
                     GVGTVAAGVAKAHADKVLISGDSGGTGASPLSSIKYAGVPWELGLAETHQTLVLNDLR
                     GRIRVETDGQMKTGRDVAIAALLGAEEYGFATAPLIIEGCIMMRKCHLNTCPVGIATQ
                     DPVLRKKFTGQPEHVVNFFFFIAEELRQIMAKLGFRTINEMVGRVDKLKIHKAVEHWK
                     AKGLDLAPLLKMPEVGPEVPRYCVQKQDHGIAEILDRALIEQCAPAIDRGQKVTLELP
                     IRNLNRTVGTMLSSQVSKKYGQDGLPVDTITIKFNGSAGQSFGAFLSRGITLILEGES
                     NDYIGKGLSGGKIIVFPPKNAIYTPEETILVGNTSLYGGTQGEAYFYGMAGERFAVRN
                     SGVRAVVEGTGDHGCEYMTGGVVAVLGRTGRNFAAGMSGGVAFVLNELDKFQSRCNLG
                     MVELEPVVSDEDKRLLHDMITSHFLYTGSRNAKRILDGWEAILPKFVKVMPIDYKRVL
                     AERKAAAAKVQK"
     gene            5435..6439
                     /locus_tag="PK063_17075"
     CDS             5435..6439
                     /locus_tag="PK063_17075"
                     /inference="COORDINATES: protein motif:HMM:NF012568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HMZ98817.1"
                     /translation="MSNGPTTLTLHSMADVWDVYREELEGVEEQIRKNLDSSVDLVNT
                     VAAHILNSGGKRVRPLFVLLSAHLCGYAGQDHQALGSLVEFIHTATLLHDDVVDDADL
                     RRGRRTASKVWGNQISILVGDYLYSRAICQIVDFRNQGINEALSEACRKMAEGEVLQL
                     YYNGNPLMPEPEYLRIIEHKTAGLIAASCKIGAIVGGATEELQEALFRFGQRLGIAFQ
                     LADDTLDYTANGEHLGKTLGQDLRQGKATLPLLHLLQHCPEPDRQLIKDRMETRTLTD
                     EELRRIVALMQEYGSIAYAMERAHAFVAAAKRDLDLFHDNTAKRALSIAADYMVTRDR
                     "
     gene            6710..8032
                     /locus_tag="PK063_17080"
     CDS             6710..8032
                     /locus_tag="PK063_17080"
                     /inference="COORDINATES: protein motif:HMM:NF018004.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HMZ98818.1"
                     /translation="MAHIIPFHGTLYNPTTVGDVRKVVAPPYDIIDSTLQKTLHDRHP
                     NNVIRLELGYEQAGDAPANNKYTRAAAALTDWLKSGALRKDSQPAVYYHTIEYRPPYS
                     APGTPTKVFKGFLSTVELEEFGSGKIYPHENTRAAAKTDRLNLLEACRANFSAIISLY
                     SDPQNEVLNLLEQSIASEKPRIDFQDDEGFRQQLWSVTDAKVLAKVVQIMNTKQLFIA
                     DGHHRYETALNYRKSRRQQAGAATSPQPYDNVLMLFASLEDKGLTVLPTHRVLTTPVP
                     ATKDLLGKFEPVFEVAALPLQAGNESQVRAQFIERLRSQGQSVPMFGLALKNDSNYYL
                     LTLRESHRPTASASPRDRLDVSLLQQHVIATLCPSQQEQEAMLYSKDDHEALNWVRQG
                     KGTAALLLNPTKVAEVKAVASAGERMPHKSTYFFPKPLTGLVMNVMEG"
     gene            8052..>9346
                     /locus_tag="PK063_17085"
     CDS             8052..>9346
                     /locus_tag="PK063_17085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ98819.1"
                     /translation="MKAKVLIVDDDQDIVTMLQDRLDAGGYKTLTAGDGQRGLELIEQ
                     ESPNLVLLDLYLPRLKGMDVLKRMAQNKQCEEIPVIVMTAAGTIPDAVEAMRHGAYDF
                     LTKPLEKDHLLIVIQKALERDSLKRQVAALKSDVQNRYATIVGESQKIRGIIESAQRA
                     AKSDASILLLGESGTGKELFARSIHQWSPRQSMPMVVINCVALTETLLENELFGHERG
                     AFTGADRLQKGKLEMAEGGTVFLDEIGDMPLPLQAKLLRVLQDKEFQRVGGTRSVSVN
                     IRFIAATNKDLRQSVKAGQFREDLFFRLNVVSFTLPPLRERSEDIVQLAEFFLKRHAY
                     EAKRPGVTLSPAARAALTHYSWPGNIRELDNVLSRAVVLSPSDVIEPEFLALTPEDAA
                     GKSGADHALPYLNLTYHESMEAHSAYIIDRALEKAAGNQT"
BASE COUNT         1963 a         2930 c         2612 g         1841 t
ORIGIN      
        1 cggtcgatga cccacttctc catcttgaaa tcagggatgc cgtaccgcag caagccgccg
       61 atacgatcgg ccttctcaaa tacggtgacg ctatgaccgg cgcgcgcgag ttgttgcgcg
      121 gcagccagac cggcagggcc tgatccgatg atggcgaccg tcttcccggt ctttctcacc
      181 ggcaaggccg gctcgaccag gccttcgttg aagccacgat cgataatgtt ccattcgagc
      241 acgcggatcg acaccgggtc gctattgatg cccagcacgc aggcgccttc gcagggcgcg
      301 ggacagagac ggccggtgaa ttccgggaaa ttgttcgtgg tgtgcaacgc cttcagcgca
      361 tctttccagc gtccgcgata gacgagatcg ttccactcgg gaatcaaatt cacgacggga
      421 caaccggtat tgccctggca aaaaggcaca ccacaatcca tgcagcgggc accttgaacc
      481 ttgagcttct cctccgggat gggctcgtac atttctttcc aatcgagcac gcgcaactcg
      541 atcggtttcc gcttcggccc ctcacgcgcg tatttcagaa agccctttgg atcacccatc
      601 gctaattcgt ctctcgtcct tcgtcactcg tctatcgact ggattgctca cacgtgcgcg
      661 tcaccagacg cgcgctatct atttttgcac tttggccgca gcggccttcc gctcagcgag
      721 cacacgcttg taatcgatcg gcatgacctt cacgaacttg ggcaggatcg cctcccagcc
      781 atccagaatc cgcttggcat tccggctgcc ggtatagagg aagtgcgacg tgatcatatc
      841 gtgcaacagc cgcttgtcct catcgctgac aaccggctcc aactccacca tgcctaagtt
      901 gcaacgagac tggaacttat ccagctcgtt caacacaaac gccaccccgc ctgacatacc
      961 cgccgcgaag tttctaccgg tcctgcccag gaccgccacg actccgccgg tcatatattc
     1021 acagccgtga tcgccggttc cctcgacgac ggcgcgcacg ccgctgttgc gcacggcaaa
     1081 ccgttcaccg gccatgccgt aaaaataggc ttcgccctgc gtgccaccat acaacgacgt
     1141 gttgccgacg agaatggttt cttccggtgt gtaaatcgcg ttcttcggcg ggaagacgat
     1201 gatcttgccg cccgacaggc ccttgccgat atagtcgttg gactcccctt cgaggatgag
     1261 cgtgatgcca cgcgagagaa acgcgccgaa cgactggccg gccgatccgt tgaacttgat
     1321 cgtgatcgtg tcgacaggca atccatcctg accatacttc ttcgacacct ggctcgacaa
     1381 catcgtgccg accgtccggt tcaagttccg gatcggcagt tcgagcgtga ccttttggcc
     1441 acgatcaatt gcgggggcac attgttcgat gagcgcgcgg tccaaaatct cggcgatgcc
     1501 gtgatcctgc ttctgcacgc aataccgtgg gacttcaggg ccgacctcgg gcatcttgag
     1561 cagcggcgcc agatccagcc ccttggcctt ccaatgttcg acggccttgt gaatcttgag
     1621 cttgtcgacg cgcccgacca tttcattgat ggtgcggaat cccagcttcg ccatgatctg
     1681 ccgcaattct tcggcgatga agaagaagaa attcacgaca tgctccggct gcccggtaaa
     1741 cttcttgcgg agaaccggat cctgagtcgc aatgccgacg ggacaggtat tgaggtggca
     1801 cttccgcatc atgatgcagc cttcgatgat gagcggcgcc gtggcaaacc cgtactcttc
     1861 cgcccccaac aaggccgcaa tggccacatc gcgcccggtc ttcatctggc cgtctgtctc
     1921 cacacgaatc cggccgcgca aatcgttgag caccagcgtt tgatgcgttt ccgccaaccc
     1981 caactcccac ggcacaccgg cgtacttaat cgatgacagt ggagaggctc ccgtcccacc
     2041 tgagtcgccg ctgatgagca ccttgtcggc atgggccttg gccactccgg cggctaccgt
     2101 gccgacgccg acttcggaga ccagtttcac cgagacggcc gcatcggcat tggcattctt
     2161 caagtcgaag atgagctgtg ctaagtcttc gatggaatag atgtcgtggt gcggtggtgg
     2221 tgaaatgagc tgcacgcccg gcgtggagta gcgcaaccgc gcgatgttct cgtccacctt
     2281 atgtccggga agctgaccac cttcgcccgg tttcgcgccc tgcgccatct tgatctggag
     2341 ttcttttgca ttcaccagat aatggctcgt gaccccgaac cgcgcggatg ccacctgctt
     2401 gatatagctg ttgcgggagt cgccgttcgg gagcggctcg aatcgctctg gatcctcgcc
     2461 tccttcaccc gtattgctct tggcgcccag ccggttcatg gcgatggcca gcgtctcgtg
     2521 cgcttccttg ctgatggagc cgaacgacat ggcgccggtg gtgaagcgtt tgacgatgtc
     2581 tttggccggc tctacttcgt tcagcgcaat cggttccggc aggaacttga actccagcag
     2641 gccgcgcagg ttcgagcggc gtttgctctc gtcattgacc agctgcgaaa actcggcgaa
     2701 cgtcttggga tcgttgtttc tcgtcgcgtg ctgtaacttg tagatggtat ccggattcca
     2761 gttgtggtgt tcgccctgga tccgatagtg aatctcgcca ccgaaatcta actgtcggat
     2821 cggcaccggt tcgtaggcca cgcgatggcg gcgtaacgtt tcttccccga tctcccgaat
     2881 gccgataccc tcgatccgcg acggcgtgcc ggtgaagtag cggtcgatca gttcatgatt
     2941 gaggccgatc gcctcgaaga tctgcgcgcc gcagtaggac tgcaccgtgg agatgcccat
     3001 cttcgagaaa atcttgagca agcctttgtt aatggctttg atgaacttgc cttcggcggt
     3061 cgccgcgtcc agcccttccg gaaagtatcc gtcgcgttcc agatccacca gcgattcgaa
     3121 gaccagatag ggattcacgg ttccggctcc gaagccgatc aagcaggcga aatgatgcac
     3181 gtcgcgcggc tctccggttt ccaccgtcag gcccacttcc gttctcgtgc attcccgcac
     3241 cagatggtga tggaccgccg caacaccgag aagactcggg atcggcgccc attcggcatt
     3301 cacgccgcgg tcgctgagga tcaggaactt gtacccctca cgaatcgcct gcgacgcctg
     3361 ccgacagaga tcgtccaccg ccgcgcccaa tccttccgga ccttcggcga cgcggaacaa
     3421 catcttcaac gtcttgctct tgaagtgcgg atcggcgatc tcccggatct tgtgcagatc
     3481 ggcattggtc aaaatcggct gcttcacccg gatgcggcgg gccgattccg gatgctcatc
     3541 catcagattc ggcttggggc cgatgctggt ggtgagggac atcacgagtt cttcgcggat
     3601 cggatcgatc ggcggattcg tgacctgcgc aaagagttgc ttgaagtatt taaagagcag
     3661 ctgcggccgt tcagacaaca ccgcaagcgg cgtatcggtg cccatcgagg agatggcttc
     3721 ctgcccttcc accaccatgg gggtgatgac catcttcagt tcttcgatgg tatagccgaa
     3781 cgcctgctga cgctgccgga tcgtgggatg atcgggctgc gggacgttga tcggatcggg
     3841 caactcatcc agggaaatgc gatgctcggt gacccaggac cggtacggct tacgacgaac
     3901 gatatcggct ttgacttcct cgtcgtcgat gatacggccc tgttcggtat cgaccaggaa
     3961 catacggccc ggcatcaacc ggcctttttg acgaatgcgc tgcggatcca tcggcaggac
     4021 accggcttcg gaagccagga caaccaatcc atcggtcgtc acctgatacc ggcaggggcg
     4081 aagcccgttc cggtccagcg tggccccgat caacttcccg tcggtgaaac acacggcggc
     4141 gggaccatcc cagggttcct gcatagcagc gtggtactca tagaatccac ggcgatccaa
     4201 atccatctgc ggattggcca cccagggctc ggggatcagc atcatcatgg cgtgcggcaa
     4261 tgaccgcccg cccaagacca ggaattccag cgcattgtcc aagctggccg agtcgctctg
     4321 attctcatag acgatcggga agagcttctt catgtcttcg ccgaacaact cggagttcag
     4381 ccgcccctgc cgcgcgcgca tccaattcac attgcccttc aacgtattga tctcaccgtt
     4441 gtggcagatg tagcgataag gatgggccag cggccaggtg ggaaacgtat tcgtgctgaa
     4501 gcgagaatgc accagcgcca tggcgctcgt caggctgctg tcggtcagat cctggtaata
     4561 ctgcgggatc tgatgcggga gcaggagccc cttgaacacg atggtgctgc tggagagact
     4621 cgggatgtag aaatagtccc ggccttcaat ggcggattcg cgcacggccc gttccgcgca
     4681 cttgcggatg acatacaggc gccgttcgaa ttcctcatcc gtgaagatgc cacgggcaat
     4741 gaagacctgt cgcatgaacg gctcagtgct gcgcgccacc ggtccaatgg cgtcgctctt
     4801 gaccggcaca tcacgccagc cgaggagctt cgcaccggca tctttaatga cccgggtaaa
     4861 caccgtctcg cactgcgcgc gggcatcggc atcgggcggt aagaacacca ttccgacgcc
     4921 atactctccc gctccgggca gcttgatgcc gctgtctttg gcggcacgct tgaagaactc
     4981 atgcgggact tgaagcagga tgcctgcgcc gtctccggta cagggatcac acccctgcgc
     5041 accgcgatgg gtcaggcttt ctaaaacctg aagcccctgc tgcacgatct ggtgcgagcg
     5101 ctggcccttg atatcgacga caaacccgac tccgcacgag tctttctcgt gctgcggatc
     5161 atatagccct tgtttgggag gaagccctgg tacattcatg gcacgtattc tcgtctagag
     5221 gcaggcaata aaccggggaa cagacgcccc tctcggggac gttgaagctg tcgcacgacc
     5281 acggtgactg ctaccattca gttggggaaa tcagcgagag gtcaccttac tggatgggcc
     5341 gtgaaactgt caagagaacg gcgacgcaaa ctgaagtaca aaccctccga ccagtgcttg
     5401 acttagtgga gtttcctgcc ctactatccg ccccatgtcg aatggaccga ccaccctcac
     5461 gctccacagc atggccgatg tctgggacgt gtaccgtgaa gagctcgagg gggtcgagga
     5521 acagatccgg aaaaatctcg actccagcgt cgatctcgtc aatacagtcg ccgcccacat
     5581 cttgaacagc ggcggcaagc gcgtccgacc gctgttcgtg ctcctcagcg cccatctctg
     5641 cggatacgcc ggccaggacc atcaggccct gggaagcctt gtcgaattca ttcataccgc
     5701 caccctgctg cacgacgacg tcgtggacga cgccgacctg cgccggggcc gccgtaccgc
     5761 gagcaaggtc tggggcaacc agatcagtat tctggtgggg gattacctct attcacgggc
     5821 catctgccag atcgtcgact tccgtaacca aggcatcaac gaagcactct cggaagcctg
     5881 ccggaagatg gccgaaggcg aagtgctcca actgtattac aacggcaatc cgctgatgcc
     5941 ggaaccggaa tacctccgca tcattgagca taagaccgcc ggattgattg ctgcctcgtg
     6001 caagatcggc gcgattgtcg gcggggccac ggaagaatta caggaggcgc tgttccgctt
     6061 cggacagcgg ctgggcattg cattccaact ggcggatgac acgctggact acactgccaa
     6121 cggcgaacat ctgggcaaaa cattggggca ggaccttcgg caaggcaaag cgacgctgcc
     6181 gctgttgcat ctgttgcaac actgcccgga accagaccgg cagttgatca aagatcgcat
     6241 ggaaacccgg actttgaccg atgaggaact gcgccgcatc gtcgccttga tgcaggagta
     6301 tgggtccatc gcctacgcca tggaacgggc gcacgcgttt gtcgccgccg cgaaacgcga
     6361 tctcgatctg ttccacgaca acaccgccaa gcgcgccctg tccatcgccg ccgattatat
     6421 ggtgactcgc gaccgctgag ttgccgccgt ccggcttcta caacgcccac gctctgctga
     6481 ccgcacgtac tcgttcagcg acgggtctct ttcgccacgg gatgaaccga taaccatgtt
     6541 aagcccctac cactaccacc gcggtcataa gacgcttcac gttgcattca gtgacagagc
     6601 gaccgccgca ggttattcgg aaaggccgtc aatgagtccg gcaatcggca gcctttccca
     6661 acaacccgta tgccaccctg catccatcga gcaaaaagga tagaatcgca tggcacatat
     6721 cattcccttt cacggcaccc tgtataatcc cacgacggtc ggcgacgtcc gaaaagtggt
     6781 cgcaccgccc tacgacatca tcgacagcac gctgcaaaaa acgttgcacg atcgccaccc
     6841 gaacaacgtc atccggctgg aactcggcta cgaacaagca ggggacgcac ctgccaataa
     6901 taagtacacc cgcgccgcgg ctgccctgac cgactggctg aagagcggag ccctccgcaa
     6961 agattcccag ccggcggttt actaccacac catcgaatac cggccgccct actcggcacc
     7021 tggcacaccg accaaggtct tcaaagggtt cctgtctaca gtggagctcg aagaattcgg
     7081 ttcgggcaag atctatccgc acgaaaacac ccgcgcagca gcgaaaaccg accggctcaa
     7141 tctcctggaa gcctgccggg ccaacttcag cgcgatcatt tcgctgtatt cggatcccca
     7201 gaatgaagtg ctcaatttgc tcgaacagtc gattgcgtcg gagaaaccgc gcatcgattt
     7261 ccaggacgac gagggcttcc ggcagcagtt gtggagcgtc accgatgcga aggtcctcgc
     7321 aaaggtcgtc cagatcatga acacgaaaca actgttcatc gccgacggcc atcatcggta
     7381 cgaaacggct ctcaactacc ggaaatccag acggcaacag gctggagccg ccacctcacc
     7441 gcaaccgtac gacaatgtgc tgatgctgtt cgccagcttg gaggacaagg gcctgaccgt
     7501 gctgccgacc catcgggtcc tgacgacacc ggttccggcg acgaaggatc tgctggggaa
     7561 attcgagccg gtgtttgagg tcgctgcgct cccccttcaa gcaggcaatg aatcgcaggt
     7621 gcgcgcgcag ttcatcgaac ggctacgcag ccagggacag tccgtgccga tgttcggttt
     7681 ggctctgaag aacgattcga attattacct gctgaccctg cgggaatccc atcgccctac
     7741 ggcctccgcg tcaccgcgcg atcggctgga cgtgtcgctg ctacagcagc atgtgattgc
     7801 cacgctctgc ccgagccagc aggagcagga agccatgttg tattccaaag atgatcacga
     7861 agcgctgaac tgggtgcgcc agggaaaagg cacggccgcc ctcctgctca acccgacgaa
     7921 agtggccgaa gtcaaagcgg tcgcctcagc gggcgaacgg atgccccaca agtcgaccta
     7981 cttctttccc aagccgctca ccggcttggt catgaatgtg atggaaggct aggcgccgga
     8041 cacagggttc gatgaaggcc aaagtcctca tagtcgatga cgatcaagac atcgtgacga
     8101 tgttacagga tcgccttgat gcgggcggat acaaaacgct caccgcgggc gacggccagc
     8161 gtgggcttga actcatcgag caggaatcgc ccaacctggt cctgctggat ctgtacctgc
     8221 ctcgcctcaa aggcatggac gtcctgaaac gcatggccca gaacaagcaa tgcgaagaaa
     8281 tcccggtcat cgtcatgacg gccgccggca ccattccgga tgccgtggaa gccatgcgcc
     8341 atggcgcgta tgacttcctg accaagccgt tggaaaaaga tcacctgctg atcgtgattc
     8401 aaaaagcgct ggaacgggac tcgttaaagc gacaggtcgc cgccctcaag tccgacgtcc
     8461 aaaaccgcta tgccaccatc gtcggggaaa gccaaaaaat caggggcatc atcgagtcgg
     8521 cccagcgtgc ggccaagtct gacgccagca ttctcctgct gggcgaaagc gggaccggca
     8581 aggaactgtt cgcgcgctcc attcatcaat ggagcccccg tcagagcatg ccgatggtcg
     8641 tcatcaactg cgtggccctc accgaaacgc tgctcgagaa cgaactcttc ggccacgaac
     8701 gcggcgcctt caccggcgcg gaccggcttc agaagggcaa actcgaaatg gcagagggcg
     8761 gaacggtttt tctcgacgag atcggagata tgcccctgcc gttgcaggcc aagctactgc
     8821 gcgtcctgca agacaaagag tttcaacgcg tcggcggtac ccgctcggtg tccgtcaaca
     8881 ttcgtttcat cgcggccacc aataaggatc tccgacaatc ggtgaaggcg ggccagttcc
     8941 gcgaggattt gttcttccgg ctcaatgtcg tcagctttac actccctccc ttgcgggaac
     9001 gaagcgaaga catcgtccaa ctggcggaat ttttcctgaa gcggcatgcc tatgaagcga
     9061 agcgcccggg cgtcaccctc agccccgcgg caagggctgc gctgactcac tactcctggc
     9121 ccggcaacat ccgcgaactc gacaacgtcc tttcacgcgc agtcgtgctc agccccagtg
     9181 acgtgatcga accggaattt ctggccctga cccccgaaga cgccgcaggc aaaagcggcg
     9241 cagaccacgc gcttccctat ctcaatctca cctaccatga gtccatggaa gcgcacagtg
     9301 cctatatcat cgatcgggca ttggaaaaag cggcggggaa tcagac
//
LOCUS       DAOQPD010000106         8806 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_4320_length_8806_cov_23.444863, whole genome shotgun sequence.
ACCESSION   DAOQPD010000106 DAOQPD010000000
VERSION     DAOQPD010000106.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 8806)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8806)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8806
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4320_length_8806_cov_23.444863"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..914)
                     /locus_tag="PK063_17090"
     CDS             complement(<1..914)
                     /locus_tag="PK063_17090"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98820.1"
                     /translation="MRPSPEAGMGQAGRCVGSMVALCGLLLAVACGDASVDAYCEANG
                     RGNQDTLDLLTHVLEQKRNQTGIYLARARCYYFLGSYAQALQDASEVIRRLPNKADAY
                     LIRAKAGKMLGQIPQALDDYSTSIRLRPSAEAHYGRGLTYVREYQGKDREALDDFTAA
                     IRFDPKHVGAYKARAEIYSRHEQFQNALQDSEIVLKLDPATPNAYCNVGFAHYAVGHD
                     AEGRKLLNICYQKDPDPQTRGYYETEVRKVLAARQPRRNSDGGYQSDVRERTPYDREM
                     ERQQNVYESLRNSGFNDRAEACRTDGSK"
     gene            complement(1039..1824)
                     /locus_tag="PK063_17095"
     CDS             complement(1039..1824)
                     /locus_tag="PK063_17095"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HMZ98821.1"
                     /translation="MRSAGTRIVRWLLCACLAGVAQPALALDHDNLDPNRPIGMEDAY
                     AIPKGEIGLEGGVRFNDRREGRTQVTFQPQIIYGAFANTQIEIQGDLFTDPHSIVGAN
                     KSGDLHLGLLYNFNTETLILPAMAVRVEADLPTGVNSKGVDTQVTGILTRSFGRLRVH
                     LNGGYTVLGSPQGQERPGTYRAVAAVSYPLGYPGSFRDTLIASLYTRQSDLHGERNHT
                     GVEIGLRHQLTSRVVLDGGLGTEFLGPANRAALLGTVGVSLGF"
     gene            complement(1821..2735)
                     /locus_tag="PK063_17100"
     CDS             complement(1821..2735)
                     /locus_tag="PK063_17100"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98822.1"
                     /translation="MAIATVAFALAGCNQFEPRDKRFYYRALWNFSLREDLAELDSEF
                     NGVDFGHSNLYENLLLTGGQDVAAIEDRARKETLAFIATRPRLNPNEEAIAPTYMKLA
                     WRAQNTFDEAHALHRATYDIAVSDEPDKDRAIRNVLAYYKESAYAITSKQLDHRRLDS
                     FPYSKAFRQRFPLFNATIWSYHYLQVAVYDPLLAARDLTAKTQAVRPILTTYRRYLEQ
                     PPVEWTFMPLTAELSPEFAARYPDVAHIFDNLHMLHDNISDILTSERLPTWEAKRAEI
                     YRIVNTYYLATADATNPMIVQTAGEHHH"
     gene            complement(2800..3381)
                     /locus_tag="PK063_17105"
     CDS             complement(2800..3381)
                     /locus_tag="PK063_17105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4396 domain-containing protein"
                     /protein_id="HMZ98823.1"
                     /translation="MRHHHSAAAAVPRQAESDSQVHHHDHERPQPHGHAPHQAHSAER
                     HPTPSLDRTALMATLHCLSGCTIGELLGMAIGTALGWGNWSTIALAIALAFFFGYAMT
                     VYPLRRAGMAWGTALGLALASDTLSMTTMELADNAIMMVIPGAMDAGIFDLLFWGSLG
                     FSLIVAGIAAFPVNRWLIARGKGHALVHGHHCH"
     gene            3666..4172
                     /locus_tag="PK063_17110"
     CDS             3666..4172
                     /locus_tag="PK063_17110"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98824.1"
                     /translation="MPSGIHRTLYTLFFLLLAPLTTQAADLPNTSLTPLRFLVGEWKG
                     TDADGKAHKSAFTLSSGGTTLTEVLTPPDSPPMTTMYYSDGDQLMLTHYCSLDNQPRM
                     RAAAVKDGDKTITFSFVDATNLKNPTDVHMHQLAIDVKDHDHFTQTWTLSKAGKDVPK
                     VFTFERVK"
     gene            4206..5063
                     /locus_tag="PK063_17115"
     CDS             4206..5063
                     /locus_tag="PK063_17115"
                     /inference="COORDINATES: protein motif:HMM:NF024880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HMZ98825.1"
                     /translation="MPSQTPAAVIEAQREDWNRVAAGWDKWDQFFNRTMAFINHRLVA
                     DARIRPGLRVLDLGSGTGYPAILAGEVVGADGTVVGMDLAESMLAVATRKAKTLGLHQ
                     VSFRTGDVTSLPFDSGSIDSIISRFCLMFLPEIPKATAEIARVLKPGGYVAAAVWSSP
                     DNNPFIRIPMDVIKTILPLPPPDPEAPGIFRLARPGDLAGMFERAGLTVLDDEEFTAE
                     VTYTTAEEFFRGLMDIAAPIQNLFAKLTPAQQTEAERGIIKTVNEYKRAEGVSLPIAV
                     RIVSARKPK"
     gene            complement(5131..5409)
                     /locus_tag="PK063_17120"
     CDS             complement(5131..5409)
                     /locus_tag="PK063_17120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98826.1"
                     /translation="MRTFMTVAAVVVCFSTALVFSADASETKAKMEKAKGDMKGNVEE
                     MKGETKAMNEELKGNDTKAEVERAKGKMKGAKERAKGKMKQLKEKATD"
     gene            5609..6043
                     /locus_tag="PK063_17125"
     CDS             5609..6043
                     /locus_tag="PK063_17125"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98827.1"
                     /translation="MRHLILSGLLGFVILTTSGCSYLFYPHAKEFTEKAKGGNTVETL
                     INLTNMMEASAKAGQQGKGKDQALDDLHNQLHAFNNTICCVDKNKQETPAYALAVTHN
                     KELWAIFKRVWKFKDDQPQRSQHLELFVTEVRELRESLQALK"
     gene            6209..6580
                     /locus_tag="PK063_17130"
     CDS             6209..6580
                     /locus_tag="PK063_17130"
                     /inference="COORDINATES: protein motif:HMM:NF016854.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
                     /protein_id="HMZ98828.1"
                     /translation="MRPDSFKDFVVDQLGEVPQLMCKAMFGGHGLYQRETFFGIIHKG
                     RLYMKTNGMTQSAYTARGMQPFRPNGKQLLRHYYEVPVDILEDAEQLTDWALRAITPP
                     TAQLILPFHDNPSIKDVLTHM"
     gene            6580..7152
                     /locus_tag="PK063_17135"
     CDS             6580..7152
                     /locus_tag="PK063_17135"
                     /inference="COORDINATES: protein motif:HMM:NF016246.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HMZ98829.1"
                     /translation="MNQELTTPSRRLWTIGHSTRSSDEFLALLHVHDIQRLIDVRRHA
                     GSRRYPHFHSDALAKSLPMAGLSYEELPALGGRRTARADSPNSGWKNASFRGYADYMQ
                     TEEFDRALEELMAQGENDRTAIMCAEAVPWRCHRSLVADALVARGWDVTHILGGGQGK
                     PHQLTTFAMIQAGRVIYPAPSDQCSTLRMF"
     gene            7204..7575
                     /locus_tag="PK063_17140"
     CDS             7204..7575
                     /locus_tag="PK063_17140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2784 domain-containing protein"
                     /protein_id="HMZ98830.1"
                     /translation="MWYRTGADFVLLLHVSFVLFVIAGGLLLLKWRGLAWIHLPAVAW
                     GVLVELTGWICPLTPLENHLRSLAGESSAEGDFVGRYLPSLLYPAALTREIQLLLGIL
                     VLLVNLALYWQVFFRTKGEQT"
     gene            complement(7587..8171)
                     /locus_tag="PK063_17145"
     CDS             complement(7587..8171)
                     /locus_tag="PK063_17145"
                     /inference="COORDINATES: protein motif:HMM:NF024375.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HMZ98831.1"
                     /translation="MTDPRREEDVTELAALYALEALGDDAQRQFARSLETASASTKDE
                     VASFQDVVQELAFSGPAIAPPASLKARLMARIAQEPQEQAEGTGFSFVRSRDVSWQEL
                     APGLSMKVLFHDAAGARTTMLLRLAPGGTLIGHRHPQVEEFYVLEGSCLCAGELLQVG
                     DYHRAEAGTVHSVTSSEQGCLALVMTSSKNEPIR"
     gene            complement(8168..>8806)
                     /locus_tag="PK063_17150"
     CDS             complement(8168..>8806)
                     /locus_tag="PK063_17150"
                     /inference="COORDINATES: protein motif:HMM:NF019265.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HMZ98832.1"
                     /translation="GCARRTSRGHPMCDTQTVANAPSIHEQEWAGLLARIAVGDQSAL
                     AELYDASSAKVFGLAMKILGDHAAAEETTLDVYTQVWRRISTYDAERGTPGSWLMTLA
                     KHRAIDRFRSSYLERGRQVPLEQAAELPGCGDTPEQYSAGLERQRLVQDALATLSAEQ
                     RQAIALAYYWGMSQSEIAEQLKLPLGTVKTRIRLGMIKLREVLAPHGEGLLS"
BASE COUNT         1780 a         2696 c         2480 g         1850 t
ORIGIN      
        1 cacttcgatc catccgtccg gcatgcctcc gcacgatcgt tgaaccctga attgcgcagg
       61 ctttcgtaca cattctgctg ccgttccatt tcccgatcgt agggagtcct ttcccgcaca
      121 tccgactgat acccgccgtc ggaatttcgc cttggctgcc gcgccgccag taccttgcgc
      181 acctcggttt cataatagcc gcgcgtttgg gggtcgggat ctttctggta gcagatgttc
      241 aagagcttgc ggccttcggc gtcatgtccc acggcgtaat gggcgaatcc gacattgcag
      301 taggcgttcg gcgtcgccgg gtcgagcttc aggacaattt cagaatcctg cagggcgttc
      361 tgaaactgtt cgtggcggct gtagatttcg gcgcgggctt tgtaggcgcc gacatgtttg
      421 gggtcgaaac ggatggcggc cgtgaaatcg tcgagggctt cgcggtcctt cccttgatac
      481 tcccggacgt aggtcaatcc gcggccatag tgagcttcgg cactgggacg aagccggatc
      541 gatgtcgaat agtcgtccaa ggcttgcgga atctgaccaa gcatcttgcc ggccttggcg
      601 cggatgagat aggcgtcggc cttgttcggc agacggcgaa tgacttccga ggcatcctgc
      661 agtgcctgcg cgtacgaccc gagaaaataa taacagcggg cccgagcgag ataaataccg
      721 gtttgattac gtttttgttc gagtacgtgg gtgagaaggt cgagggtgtc ttggttgccc
      781 ctgccgttgg cttcgcagta ggcatccacc gaggcatcgc cacaggccac cgccaggaga
      841 aggccgcaca gcgcgaccat actgcctaca caacgaccgg cttgtcccat gcccgcctcc
      901 ggagacgggc gcattatctg ctcgtagaac aaacaacgtc aagactgtca tcacaactac
      961 tacccaagag attatacgag gcaacgtgcg gtggatggcc acccctgatt cgcgtcccag
     1021 ctcaactgac gaatcggcct aaaatcccaa ggagacacca accgttccaa gcaaggccgc
     1081 ccgattggca ggaccgagaa attccgtccc gagcccgcca tccagcacaa cccgcgaggt
     1141 gagctgatgg cgcaagccga tttccacacc ggtgtggttt cgctctccat gaagatcgga
     1201 ctgtctggtg tagaggctgg caatcaacgt gtcgcgaaaa ctccccggat atcccagcgg
     1261 ataactgacc gccgcgacgg cacggtaggt gccgggccgc tcctgtcctt gcggagagcc
     1321 gagcacagta tacccgccat tgaggtgcac ccgcagccgc ccgaacgacc gggtcagaat
     1381 cccggtcact tgcgtatcga cgcccttcga attcacaccg gtcggcagat cagcttccac
     1441 gcgtaccgcc atggccggca gaatcagcgt ttccgtgttg aagttgtaga gcaggcccag
     1501 atggagatcc ccggatttgt tggctcccac aattgaatga gggtcagtga acaggtcgcc
     1561 ctgaatttcg atctgcgtgt tggcgaacgc gccatagatg atttgcggct gaaaggtgac
     1621 ctgcgtgcgg ccttctcgac gatcgttgaa tcgcacgccg ccttccaggc cgatttcccc
     1681 tttgggaatg gcataggcat cctccatccc gatggggcga ttcgggtcga ggttatcatg
     1741 gtccaacgct agagcgggct gggccacacc tgccaggcat gcgcagagca gccaccgcac
     1801 gattcgtgtg cccgcactcc tcaatggtga tgctccccgg ccgtctggac gatcatggga
     1861 ttcgtcgcat ccgccgtcgc caggtaatag gtattcacga tgcgatagat ttccgcccgc
     1921 ttcgcctccc acgtcggtaa ccgttcgctt gtaaggatat cgctgatatt gtcatgcagc
     1981 atgtgcagat tgtcgaagat atgcgcgaca tccggatacc gtgcggcgaa ctcggggctc
     2041 agttccgcgg tcaacggcat gaacgtccac tccacaggcg gctgctcgag ataccggcga
     2101 taggtcgtga gaatggggcg caccgcttgg gtttttgccg tcaggtcgcg agccgccagc
     2161 aacggatcgt ataccgcgac ctgcagatag tggtacgacc agatggtcgc gttgaagaga
     2221 gggaaccgct gccggaacgc tttggaatag ggaaacgaat ccaggcggcg gtggtccaat
     2281 tgcttggacg tgatggcgta cgcgctctct ttataatagg ccaatacatt ccggatcgca
     2341 cgatccttgt ccggctcatc cgacaccgca atgtcatagg tggcgcggtg aagggcatgc
     2401 gcttcgtcga acgtgttctg cgcgcgccag gccagcttca tataggtggg ggcgatggct
     2461 tcttcgttgg gattcaaccg cggtctggtc gcgataaacg caagggtttc cttgcgcgcc
     2521 cgatcctcga tagccgcgac atcctgaccg ccggtcagca gcaggttttc atacaaattg
     2581 gaatggccga agtcgacccc attaaactcg ctgtccagtt cggccagatc ttcccggagc
     2641 gaaaaattcc agagggcacg gtaatagaac cgcttgtcgc gcggctcaaa ctgattgcac
     2701 ccggccagcg cgaaggcgac cgtggctatc gccacgatcg ccatcctccc aaggatagta
     2761 ccgccagatt tcatgtcggt cgttccaact ccatacgtct tagtggcagt ggtgcccatg
     2821 caccagcgca tggcctttgc cccgcgcgat caaccatcga ttgacgggaa aggccgcgat
     2881 tccagccacg atcagcgaga agcccagact gccccagaac agcaggtcaa atatcccggc
     2941 gtccatcgcg ccgggaatga ccatcatgat ggcattgtcg gcaagttcca tggtcgtcat
     3001 cgacaacgta tctgatgcca gggccaaccc cagcgccgtt ccccatgcca taccagcccg
     3061 ccgcaaggga tagacggtca tggcatagcc gaagaagaac gccaacgcaa tagcgagggc
     3121 gatcgtagac caattgcccc agcccagcgc cgtgccgatt gccattccga gcagttcgcc
     3181 gatcgtgcac ccgctcaagc agtgcaaggt cgccatgagc gccgtgcggt cgagcgaggg
     3241 tgtcggatgc ctctctgcac tgtgcgcctg atgcggtgca tggccatgag gctgtgggcg
     3301 ttcatggtca tgatgatgaa cctgactgtc tgactctgcc tgccgtggta cggctgccgc
     3361 tgcggaatga tgatgcctca tgcgcatcct ccctgtaagt ggtgactgat accgtgcacc
     3421 actacagacg gaaaaaggcg gaaatcatta cagggacgaa aggacaccag ttcgcagggg
     3481 gtgcggactg aatcacccat ctcgtcgctc tcactgattg ttcgaatacg tgtatttctg
     3541 actcattgaa tcccctcctg ctgtttgctt ttgcgacaac gcgggaaaaa gtcttgatct
     3601 caaccttgga gacatgcttg actgaacgct gttccgcatt cttctcagtt tactggaggg
     3661 tttgcatgcc gagtggaatc catcgcactc tctatacgct cttctttctt ctcctcgctc
     3721 ccctcaccac tcaagccgcc gacctaccta ataccagcct cacgcctctc agatttctgg
     3781 tcggagaatg gaaagggacg gatgcggacg ggaaagctca caagagcgcc ttcaccctga
     3841 gctccggcgg cacgaccctc accgaagtcc tcacgcctcc tgatagcccc ccgatgacga
     3901 ccatgtacta cagcgacggc gaccaactga tgctgacgca ttattgctcg ctcgataacc
     3961 aaccgcgcat gcgcgccgcc gcggtcaaag acggagataa gaccatcacg ttttctttcg
     4021 tggatgcgac gaatctcaag aatccgaccg atgtgcacat gcatcagctg gccatcgacg
     4081 tcaaagacca cgaccatttc acccaaacct ggaccttgag caaggctgga aaggacgtgc
     4141 cgaaggtgtt tacctttgag cgcgtcaaat agcttccacg tcgtggatca acaaggagcc
     4201 tcccgatgcc atcacaaacg ccagcagccg tgatcgaagc ccagcgtgag gattggaacc
     4261 gcgtcgccgc cggctgggat aaatgggatc agttcttcaa tcgcacgatg gccttcatca
     4321 atcaccggct ggtggcggat gcgcgtattc gtccggggct tcgggtgttg gacttggggt
     4381 ccgggaccgg gtatccggcg atcttggccg gtgaagtggt gggagctgac ggaacggtgg
     4441 ttggaatgga tctcgccgaa tcgatgctgg ccgtggcgac acgcaaggca aagacgctcg
     4501 gcctgcacca ggtcagcttc cgaaccggag acgtgacgtc attgccgttc gactccggct
     4561 cgatcgattc gatcatcagt cgattctgtt tgatgttcct cccggaaatt cccaaagcca
     4621 cagcggaaat cgcccgcgtg ctgaaaccgg gaggatatgt cgcggccgcc gtctggtcga
     4681 gccccgacaa caatccgttc attcgtattc caatggacgt gatcaaaacc atcctgccgc
     4741 tgccgccgcc ggaccctgag gcgccgggga tattccgcct tgcgcgtccg ggcgacctgg
     4801 ccggcatgtt cgagcgcgcc ggtctcacgg tgctggacga cgaggagttt acggccgaag
     4861 tgacctatac gactgcagaa gaattttttc gcgggctgat ggatattgcc gcaccgatcc
     4921 aaaacctctt tgccaaactg accccggccc aacaaaccga ggcggagcgc gggatcatca
     4981 aaacggtaaa cgagtataaa cgagcagaag gcgtgtcgtt gccgattgcc gtgcggattg
     5041 tgagtgcgcg caagccgaag tagaacgata agtgagggcg cctgcccgcg acttgtgtgt
     5101 gtcacgggcg ggcgccgcac tcttctaaat ctagtccgtg gctttttctt ttaattgctt
     5161 catctttccc ttcgcccgct ccttggcccc cttcatcttg cccttggccc gctccacttc
     5221 ggccttcgta tcattccctt tcagttcttc attcatggcc ttggtttcgc ccttcatctc
     5281 ttccacatta cccttcatgt cacctttggc cttctccatc ttggctttgg tctcactcgc
     5341 atccgccgag aaaaccagtg ccgtcgagaa acacactact accgccgcga ctgtcatgaa
     5401 tgtacgcata tccgtcctcc gagtataggt gaaccgctgt cactaatctg cgggatccgt
     5461 ctgcatcccc ccactagaga atcccctagt atcgagatga atccgtcccc cctactgccc
     5521 agggttcccc ccagttgaac cactgcgcag gccgcgacac actcgtctcg acagcctgtg
     5581 tcttaatgtc tcagaaagga gccagctcat gcgacacctc attctttccg gcctcctggg
     5641 cttcgtgatc ctcacgacca gcggatgcag ttatctgttc tatcctcacg ccaaggagtt
     5701 tacggagaag gcgaagggtg gaaacacggt tgagacgctg atcaacctga cgaatatgat
     5761 ggaggcatct gcgaaggccg gacagcaagg caaaggcaaa gaccaggcgc ttgatgatct
     5821 gcacaatcag ctgcacgcgt ttaacaacac gatttgctgt gtcgacaaga ataagcagga
     5881 gacgccggcc tatgccctgg cggtcacgca caataaggaa ctctgggcga ttttcaaacg
     5941 ggtctggaag ttcaaggatg atcaacccca acgcagccag catttggagc tgtttgtcac
     6001 agaagtgcgg gaactccggg agtcactcca agcattgaaa tgaaggccgg aatgttgcac
     6061 agtgcgccac ggcggggagc cagccttcct gactctccgc cggtgcaacg ttcacgatgc
     6121 tcgcgcggtt cgtgagactg cccctgtcga atcgactggt gaaggcagtc catgtccacg
     6181 cggcgagcgt cgaaagggtc tctggcgcat gcgtcccgac agtttcaaag acttcgtggt
     6241 ggaccaactc ggtgaggtcc cgcaattgat gtgcaaagcc atgttcggcg ggcacggtct
     6301 ctatcagcgc gagacgttct ttggcatcat tcacaaaggc cggctctaca tgaagacaaa
     6361 cgggatgaca caatcggcct ataccgcgcg aggcatgcag ccgtttcgcc cgaacggcaa
     6421 gcaactcctc agacattatt acgaagtacc ggtggatatt ctggaagatg ccgagcagtt
     6481 gacggattgg gcgcttcggg ccattacccc accgacggcg caattgattc ttccctttca
     6541 cgacaatccc tcgatcaagg acgttctcac gcacatgtga tgaaccagga actcaccacg
     6601 ccttcccgac gcctctggac tatcgggcac tcgacccggt caagcgacga gtttctcgcc
     6661 ctccttcacg tccacgacat ccaacgactc attgatgtcc gtcgtcatgc cggctctcgg
     6721 cgatatccgc actttcattc agatgcgttg gccaagagtc tccccatggc gggactatcg
     6781 tacgaagaac tgccggccct cggcggccgt cgaacggccc gagccgactc gcctaacagc
     6841 gggtggaaga atgccagttt ccgaggatat gccgattaca tgcagacgga agagttcgac
     6901 agggcactcg aggagctgat ggcccaaggc gagaatgacc ggacagccat catgtgcgca
     6961 gaagccgtgc cctggcgttg ccatcgttca ttggtggccg atgcccttgt cgcacgtggt
     7021 tgggacgtca cccatattct gggcggaggc caggggaagc cgcaccagct cacaaccttc
     7081 gcaatgatcc aggccggccg tgtcatctat cccgccccct ctgatcagtg ctccactctc
     7141 cggatgtttt agacatttcg ctgctcattg tgttcattcc gacgttactg cacactctac
     7201 gcgatgtggt atcgaaccgg cgccgacttc gtcctgctcc tgcatgtaag ctttgtctta
     7261 ttcgtgattg ctggcgggct cctgttgttg aaatggcgag gactggcctg gatccacctg
     7321 ccggcggtgg cctggggcgt cctggtggaa ctgaccggtt ggatctgtcc tttgacgccg
     7381 cttgagaatc acttgcgaag tctggcggga gaatcgtcgg cggagggtga cttcgtcggc
     7441 cgctatcttc catccctgtt gtacccggcg gcactgacgc gcgagattca gcttctgctg
     7501 ggcatcctcg tgctgctggt gaacctggcc ctgtattggc aggtgttctt ccgaactaag
     7561 ggagagcaga catagcgatc gcttcgctat cggatcggtt cgttctttga ggaggtcatc
     7621 accagtgcca agcaaccctg ctcactggac gtgacggaat ggacggtgcc cgcctccgcc
     7681 cgatggtaat ccccgacttg caggagctcc ccggcgcaga gacagctccc ctccagcaca
     7741 tagaactctt cgacttgcgg gtggcggtgg ccgatcagcg tgccaccggg cgccagcctg
     7801 agtaacatgg tcgtgcgtgc accggcggca tcgtgaaaca acaccttcat cgagagaccc
     7861 ggtgccaatt cctgccacga cacgtcccgg cttctgacga aactgaaccc ggtgccttca
     7921 gcctgctcct gcggttcctg tgcaattcgc gccatgagcc gcgccttgag ggaagccggc
     7981 ggcgcaatgg caggaccgct gaacgccagc tcctgcacca cgtcttgaaa tgacgcaacc
     8041 tcgtccttcg tggacgccga ggctgtctcc agcgaacgtg cgaactgccg ctgtgcgtcg
     8101 tcgccaagcg cctccaaggc atagagcgcc gcgagttccg tcacgtcttc ttcgcgtcga
     8161 ggatcggtca tgacaacaac ccttccccgt ggggcgcgag cacttcgcgc aacttgatca
     8221 tgcccagcct tatccgcgtc ttcaccgtcc ccagcgggag cttcaactgc tcggcaattt
     8281 cactctgact catgccccag taataggcca gggcaatcgc ctgacgctgc tccgcggaga
     8341 gcgtcgcgag cgcgtcctgc accaatcgtt gccgttccag ccccgcgctg tattgctccg
     8401 gcgtgtcgcc gcatcccggt aattcggcgg cttgctcgag cggcacctgc cggccccgct
     8461 ctaaataact gctgcgaaac cggtcgatgg cgcgatgctt ggccagcgtc atcaaccaac
     8521 tacccggcgt gccccgctcc gcgtcatacg tcgaaatgcg tcgccagacc tgcgtgtaga
     8581 catccagggt cgtctcttcg gctgccgcat gatcgccgag aatcttcatc gccaggccga
     8641 agaccttcgc actactggca tcatacagct cggccagtgc ggattgatct cccacggcaa
     8701 tacgagcgag gagtcccgcc cactcctgtt cgtgaatcga tggtgcgttg gccacggtct
     8761 gggtgtcaca catggggtgt cctcgtgacg ttctacgagc gcaccc
//
LOCUS       DAOQPD010000107         8777 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_4340_length_8777_cov_21.441871, whole genome shotgun sequence.
ACCESSION   DAOQPD010000107 DAOQPD010000000
VERSION     DAOQPD010000107.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 8777)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8777)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8777
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4340_length_8777_cov_21.441871"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(211..1611)
                     /locus_tag="PK063_17155"
     CDS             complement(211..1611)
                     /locus_tag="PK063_17155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ98833.1"
                     /translation="MSASILIVDDEVSILNSLSSILEDEGYDVSVAKSGMEALKHCAI
                     SPPELMMLDIWMPEMDGLETLKRLRELVPSTQVMMMSGHGSIETAVKAIKLGAYDYIE
                     KPLSLENVTLRVKHALDQHRLEQENRNLRTKVERKFELIGQAPVMQQLKQLIETAGPT
                     NSRVLIGGENGTGKELVARAIHQHSHRATRPFVAVNCAAIPETLIESELFGHERGAFS
                     GATTMKRGQFEQADGGTLFLDEIADMSLSTQAKVLRALQEQQFTRVGGTKLIKVDVRV
                     LAASNKDLLQEIEKGTFREDLFYRLNVVPIVVPTLRDRREDIPLLVKHFLRVHAEEQG
                     LKIKQVSPEAMDVFMQYEWPGNIRELRNLIERLMIMVPGPVIEAAHASVALQVRPQMS
                     AAQSAAGAQPANTLLTRPYDSLRDARNAFEKEFIARKLREHHWNISRTAEDLKIERSH
                     LHRKIKLLDVEMRPEM"
     gene            complement(1660..3957)
                     /locus_tag="PK063_17160"
     CDS             complement(1660..3957)
                     /locus_tag="PK063_17160"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ98834.1"
                     /translation="MPESTDMSKLIPPGVLREKEPSSPASIESERRKRHVRPVWIVLI
                     LLLPCLALTFYYAQMAVPVGEESDSFLPSTGYAFVLLLVNLDLIGFVVLTLLLSRNLI
                     KAYFERRHRLVGSGFRAKLVAAFIGFSLIPTVLLALVASGLVNKAVDVWFNDQIEHVM
                     KDSYEVARMHHAGHVSLAINSARAISHEIFREELLLPEQRDLLVAAIARKRDEYATAG
                     IEVFSAKMETLTKALDPEVPVTVLDLPIGQLVLQVINGKQELTSVQEAQTGRLVRAGV
                     PIASSVRRGEIDGVVVVDAYVPESLLGKMESIGRQYAEYKQMKAMKNPIKAGAYLLVA
                     VITVMILFSATWFGFYVARGITVPIQRLAEATEAIAQGDLSVRIEAKATDEIGTLVES
                     FNRMTADLQGSKSKVEEANVSLRQSNLELDRRRAYIETVVDTIAAGVLSIDRQGIVTT
                     FNPSAERMLGLWADRFRGRSANEVFKEYQLDLFQSVYDRMLADQRDNIALEGQLDLQG
                     RFLTIGVHCSRMKDESNKDLGFVLIFEDLSELIKAQKAAAWREVAQRIAHEIKNPLTP
                     IQLSAQRLRKKFQDKAPDFDRICDESTQVIVNEVGSLKQMLDEFSKFARMPAPHMTMN
                     SLDDVVKEVVALYESAHREIICVVSLDADLPPFNFDREQIKRVLVNLCDNGIHAMNHK
                     GRLWITTRYDTKQRRAVVTVADEGTGIAPEDQDKLFVPYFSRKKTGTGLGLAIVRRIV
                     TDHDGQIHAGNHQPKGALFTFELPV"
     gene            complement(4161..4580)
                     /locus_tag="PK063_17165"
     CDS             complement(4161..4580)
                     /locus_tag="PK063_17165"
                     /inference="COORDINATES: protein motif:HMM:NF020473.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1844 domain-containing protein"
                     /protein_id="HMZ98835.1"
                     /translation="MGDEKDQGFVIRDRRGRGEEAPAAASAPTPPAPEPAAAESHHAD
                     AHGHAGHLPVNFSSFVISMGSSALMLMGEQLDPQQPAMPLNLPQAKEIIDLLSMLEEK
                     TRGNLTPDEQVVMKDMLYALRMKFVSLTSGKSSIHTP"
     gene            4716..5612
                     /gene="mazG"
                     /locus_tag="PK063_17170"
     CDS             4716..5612
                     /gene="mazG"
                     /locus_tag="PK063_17170"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: protein motif:HMM:NF007113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HMZ98836.1"
                     /translation="MSERFDKVVAIMARLRAPGGCPWDRKQTHESLKPYLIEETYEAL
                     DTIDRRDFPKLKEELGDVLLQVLFHSQIGTEAGTFTMDDVLQELGDKLVRRHPHVFGE
                     NASGTPGLNSDQVVHRWEDIKRAERKNAGKPDSVLQDIPQALPALLRAYQTQVRAARV
                     GFDWPDSPQGLADVLGKVEEEIGELRKAVSDAGAMSQPPSEPTADMAAELGDLLFSLV
                     NLARHIKVNPEESLRQATNRFTARFQHIEHEAARSGRSVHDLTLAEMDHYWNAAKQLE
                     SADRPAAASPLASKGEASQTSL"
     gene            5609..6223
                     /locus_tag="PK063_17175"
     CDS             5609..6223
                     /locus_tag="PK063_17175"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98837.1"
                     /translation="MSSEQDPYEEGKRAGLHPLLVLFGAILVMWLLINLAVPSGKQKQ
                     AAGPEISQVGTEDPDAAPVMYKVQTTLTEFNAISILVPPQSTMSQVVGLLKQFKQARL
                     NQTLAGMLPATSPGHKLGDQAVADLYIFSDPKYASPEVVGTLARGAHAPGNLYPQAIP
                     FEEAMEQVRGHYRIDLNDTSNPDTGSIGFADDSGVHSKQYRRIF"
     gene            6524..7408
                     /locus_tag="PK063_17180"
     CDS             6524..7408
                     /locus_tag="PK063_17180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007414190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
                     /protein_id="HMZ98838.1"
                     /translation="MAKNLLTQPYLTDELKAQDFLIKMRWPEGITCVHCQGEKVYTLN
                     VRGSKRRVLKCGKCRKQFSPTVGTIFEDSHIPLTKWFMTIHLMCSSKKGISAHQLHRM
                     LGVTYKTAWFMAHRIRHAMTQLMGATPLSGIVEADETYVGGKRIGAGMGYRDHKVPVF
                     ALVQRGGEVRSMVMPRVTANTLRAAIRTNVKPTTHVMTDGATVYTNVSNDVASHETVN
                     HYEKEYVRGNVHTNTIEGYFSLLKRGITGTYHHVAEKHLHRYLAEFDFRYNARKVEDS
                     VRTFSAIQGIEGKRLQYR"
     gene            complement(7867..8244)
                     /locus_tag="PK063_17185"
     CDS             complement(7867..8244)
                     /locus_tag="PK063_17185"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98839.1"
                     /translation="MEQTQSIEELSATVKALQERVTALDYDLRSWQMKAHKYCPRCGG
                     PSVPSKPMNLPFSSLPLTDAVMMVVSEKDAPIGIRKLRAILEEKGMKEKMGRYGNNMR
                     TAITRLVKAGRLSREGDTVEMLK"
BASE COUNT         1960 a         2593 c         2373 g         1851 t
ORIGIN      
        1 atcttaacga gccaactgat agcgggtcaa caatagtctc acacactggg gcgctacgtg
       61 agtccgtcag acatcaacac gagaagggct gctcaaacag ttcatccaac gaggccgcag
      121 gggagaaaga accggaggcg taccctcggg gtacgtcgca gcgagcgtcg cgactgagaa
      181 cgcagctggc ggtcgttttc agcaacttgc ctacatctca gggcgcatct cgacatcaag
      241 taacttaatc ttccgatgta aatggctgcg ttcgatcttg aggtcttccg ccgtgcggga
      301 aatattccaa tgatgctcgc gcagtttgcg ggcaatgaat tccttttcaa aggcattccg
      361 cgcatcgcga agcgaatcgt acggcctggt cagcaaggta ttggccggtt gagcgccggc
      421 ggccgattgg gcggctgaca tttgagggcg tacttgaagt gcgacggaag catgcgccgc
      481 ctcgatgacc ggcccgggca ccatgatcat cagccgctcg atcagattcc gcaattcacg
      541 gatattcccc ggccattcat actgcatgaa cacgtccatg gcctccggtg acacctgctt
      601 gatcttcaac ccctgctctt ccgcatgcac gcgcagaaaa tgtttcacca gcaagggaat
      661 gtcctcgcga cgatcacgca aagtgggcac tacgatcggc accacgttca ggcggtagaa
      721 caagtcttca cggaacgttc ccttctcgat ttcctgcagc aaatccttat tcgatgcagc
      781 cagcacccgc acgtcgacct tgatcagctt ggtcccgcca acccgcgtaa actgttgctc
      841 ctggagagcc cgcagtactt tggcttgcgt gctcaagctc atgtctgcga tttcatccaa
      901 aaataacgtc ccgccgtcgg cctgttcgaa ctggccgcgc ttcatggtgg tggctccgct
      961 gaaggcgcct cgctcgtggc cgaacaactc gctttcaatc agggtctcgg gaatggctgc
     1021 acagttgacc gccacaaacg ggcgagtcgc cctgtggctg tgttgatgga tggctctcgc
     1081 caccaattcc ttaccggtgc cgttttcgcc gccgatcagc actcgactat tggtcgggcc
     1141 ggccgtttcg atcagttgct tcagttgctg catgaccggc gcctggccga tgagctcgaa
     1201 cttccgctcg actttggtgc ggaggttgcg attctcctgc tcgagccggt gttgatccaa
     1261 ggcatgtttc accctgaggg tcacattttc gagggacagc ggcttttcga tatagtcgta
     1321 cgcacccagt ttgatcgcct tgaccgccgt ctcgatcgaa ccgtgcccgg acatcatcat
     1381 gacttgagtg ctgggcacca gttcgcgcag tcgcttgagg gtctccagcc cgtccatctc
     1441 gggcatccag atatccagca tcatcagttc aggcggactg atcgcgcaat gtttcagggc
     1501 ctccatcccg cttttggcca cactcacgtc atatccttcg tcctcgagaa tactgctcaa
     1561 ggaattcagg atggagactt cgtcatcaac aatgagaatc gaagcagaca tgcatccccc
     1621 acatacgatc cgccaacacc cactcgaccg tccgttccct tacaccggca attcgaaggt
     1681 aaataaggcc cccttcggct gatgattccc cgcatgaatc tgaccatcgt ggtcggtcac
     1741 gatccgcctg acgatggcca accccaagcc cgtcccggtc ttctttctgg aaaaatacgg
     1801 cacaaagagt ttgtcctgat cctccggcgc gataccggtg ccttcatccg ccaccgtgac
     1861 caccgcgcgg cgttgcttcg tatcgtaccg ggtcgtgatc cacaagcggc ccttgtggtt
     1921 catggcatgg atgccgttat cgcacagatt caccaggaca cgcttgatct gttcgcgatc
     1981 gaaattgaaa ggcggcagat cggcatcgag cgacaccaca cagatgattt ctcgatgcgc
     2041 actttcgtag agcgcgacga cttccttcac gacatcgtcg agcgaattca tcgtcatatg
     2101 cggcgccggc atgcgcgcga atttcgaaaa ctcatccagc atctgcttga ggctaccgac
     2161 ctcgttgacg atcacctgcg tggattcgtc gcagatacgg tcgaaatccg gtgccttgtc
     2221 ctgaaatttc ttccgcaacc gctgggccga gagttgaatc ggcgtgaggg gattcttgat
     2281 ctcgtgcgcg atccgttgcg ccacttcccg ccaggccgcc gccttctgcg ccttgatcaa
     2341 ttccgacagg tcttcaaaaa tcagcacgaa gccgagatct ttattcgact cgtccttcat
     2401 gcgtgagcaa tgcacaccga tggtgagaaa gcgcccctgc aaatccagct gcccttccag
     2461 cgcgatgtta tcccgctggt cggccagcat gcgatcgtag acggattgaa acaggtcgag
     2521 ttgatactct ttgaacacct cgttggcgga gcggccgcga aaccggtcgg cccataaccc
     2581 cagcatgcgt tcggccgatg gattaaaggt cgtgacaatc ccctgccgat cgatcgacaa
     2641 cacccccgcg gcaatcgtat cgaccaccgt ttcgatatag gcgcgccgcc ggtccagttc
     2701 gaggttggat tggcgcaagg agacgttcgc ctcttcaacc ttgcttttgc tgccctgcag
     2761 atcggcggtc atccggttga aggattccac caacgtcccg atttcatccg tcgccttcgc
     2821 ttcgatccgg accgataaat ccccttgggc aatggcctcg gtcgcctcgg ccaaccgctg
     2881 aatcggcacg gtgataccgc gcgcgacata aaacccgaac caggtggcgc tgaacaaaat
     2941 catcaccgtg atcaccgcca ctaacagata ggcgcccgcc ttgataggat tcttcatcgc
     3001 cttcatctgt ttgtactcgg catattgccg gccgatgctc tccatcttgc cgagcaacga
     3061 ttccggcaca taggcgtcca cgacgaccac cccgtcgatt tccccgcgcc gcacgctgga
     3121 agcgatcggc acgccggcac gcacgagccg gccggtctgc gcttcctgca cagaggtcaa
     3181 ctcctgtttg ccattgatca cctgcaacac cagctggccg atcggcagat cgagtacggt
     3241 caccggcacc tcaggatcca gggccttcgt gagcgtttcc attttcgcgg aaaacacctc
     3301 aatgccggcc gtggcgtatt catcgcgttt ccgggctatc gctgcgacta acagatcccg
     3361 ctgctccggc aacagcaatt cctcgcgaaa gatctcatgg ctgatggcgc gagcgctgtt
     3421 gatcgccaac gacacatgtc cggcatggtg catgcgcgcc acctcgtagg agtctttcat
     3481 cacatgctcg atctgatcgt taaaccagac atcgacggct ttgttgacca acccgctggc
     3541 gaccaaggcc aacaacacgg tcggaatgag ggagaatccg atgaaggccg caaccaactt
     3601 cgcccgaaac ccggagccca ccagacgatg ccggcgttca aaataggctt tgatgaggtt
     3661 gcgcgacaga agcaacgtga ggacgacgaa cccgatcagg tcgagattga ccagcagcag
     3721 gacaaaggca tagccggtgc tgggaagaaa ggaatcggat tcctctccaa ccggaacggc
     3781 catttgtgca tagtagaagg tcagcgccag gcagggcagc agcaggatca ggacgatcca
     3841 gacgggccgg acatggcgct tgcgccgctc gctctcgatc gaggcgggcg acgacggctc
     3901 tttttcacgc agcacacccg gggggatgag cttgctcatg tccgtcgatt caggcatcgg
     3961 catgactccg aatccatctc ggaccctttg ggttctgcca cactataacg aattcctgag
     4021 gaaagactca aaagctgtgc cgaagccatc gcgctggtcg gaaacatgaa caagacactg
     4081 agagaggttg agaagccggt cgcaaccagg aggaagtcaa acccggtgga atagcggaac
     4141 gcgaagaggg cgatcacagg ttacggggta tgaatcgatg atttcccgga agtcaggctg
     4201 acgaacttca tcctcaaggc atacagcatg tccttcatca cgacctgctc gtccggcgtg
     4261 agattgcccc gtgttttctc ttccagcatg gagaggagat cgatgatttc cttcgcttgc
     4321 ggaagattca gcggcatagc cggttgctga ggatccaatt gctcccccat gagcatcaaa
     4381 gccgagctgc ccatggaaat cacgaaggag gagaaattga ccggcagatg cccggcatgg
     4441 ccatgcgcgt cagcatgatg ggactcggct gctgccggtt cgggagcagg aggcgtggga
     4501 gccgaggctg cagcaggcgc ctcttcaccg cggcctcgac gatcgcggat gacgaatccc
     4561 tgatccttct catcacccat gtgcgcaacc tcccgtcagt ccatcataaa atgcaggacg
     4621 gtaccctacc ataggccttg agggtgcgca aggcggcggg ccccgttgaa ggtgaagata
     4681 aactcagtta gagtggcgcc acgaggggaa accgcatgtc cgaacgtttc gataaagtgg
     4741 tggcgatcat ggcccggctc cgggcacccg gcggctgccc atgggatcgc aagcaaacgc
     4801 atgaatccct caagccctac ctgattgaag aaacgtacga agcgcttgat accatcgacc
     4861 ggcgggattt ccctaaactc aaggaagaac tcggcgatgt gttgctccag gtgctcttcc
     4921 acagccaaat cggaacggaa gccggcacgt tcaccatgga tgacgtgctc caggagttgg
     4981 gcgacaaact cgtgcgccgc catccgcatg tcttcgggga gaacgcgtcc ggcacgccgg
     5041 gtctgaattc cgaccaggtc gtgcatcgat gggaagacat caagcgagcc gagcgtaaga
     5101 atgccggaaa acccgattcg gtcttgcaag atatccctca agccctcccg gcgttacttc
     5161 gcgcctatca aacccaggtt cgcgccgcac gggtcggttt cgactggccg gacagcccgc
     5221 aagggctcgc tgatgtcctc ggcaaggtcg aggaggaaat aggggaactt cgcaaagccg
     5281 tgagtgacgc gggggctatg tcccagcctc catcggaacc taccgcggac atggcggcgg
     5341 aattgggcga cctgctcttc tccttggtca acctggcgcg tcacatcaag gtgaatccgg
     5401 aagaatcgct gcgtcaggcc accaaccggt tcacagctcg cttccagcac atcgaacatg
     5461 aagcggcgcg cagcgggcgc agcgtgcacg atctcacgct ggctgaaatg gatcactact
     5521 ggaacgccgc aaaacaattg gaatcggccg atcgtcctgc ggcagcctcc ccgctcgctt
     5581 ctaaaggaga ggcgtcgcag acttccttat gagcagtgaa caggatccat acgaagaggg
     5641 caagcgagcg ggactgcatc cgctgctcgt gctcttcgga gccattctgg tcatgtggct
     5701 gctgatcaat cttgccgttc ccagcggaaa acaaaagcag gcggccggac cggaaatctc
     5761 tcaagtcggc acggaagatc cggatgccgc gccggtcatg tacaaagtgc agacaacgct
     5821 gacggaattt aatgccatta gcatcctcgt cccaccccag tcgaccatga gccaggtcgt
     5881 cggtctgttg aaacaattca aacaggccag actcaatcag acactggccg gtatgctccc
     5941 ggcaacaagc cccggtcaca aactgggtga tcaggcagtc gccgacctgt acatcttttc
     6001 ggaccctaaa tatgcctcgc cggaagtcgt cggcacgctg gcgcgcgggg cccatgctcc
     6061 gggcaacctc tatccgcagg ctatcccgtt tgaagaagcc atggaacagg tacgggggca
     6121 ttaccgcatc gacctgaacg acacgagtaa tccagacacc gggtccatcg gatttgccga
     6181 tgattccggg gtgcacagca agcaatatcg ccggattttt tgagcagatc tctcgaaatc
     6241 ccacgcctga cgcgccttcg ctatccccaa gctaaaatcg gtcagcaaat atccccctag
     6301 gggttttcct cttctacagc atctagtggc ctgcgccagg acgaccccca atgcctaaaa
     6361 cttgtgcagg ccgctgaagg accagtctac gaagggcctc gagccgccat aggcccccta
     6421 tacacatcct tatccacaga ttctgtgtgt gagataaccg tgattatata cttgacacac
     6481 ccacgagtca aggcgtacac ttcgaccata acgaggtgat gccatggcga agaatcttct
     6541 cactcagccc tacttaaccg atgaactgaa ggcccaggac ttcttaatta agatgcgctg
     6601 gcctgaaggc atcacctgcg ttcattgcca aggcgagaag gtctatacgc tgaacgtgcg
     6661 cggctcaaag cgcagagtgt tgaagtgtgg caagtgccgc aagcagttct ctccgaccgt
     6721 tggaacgatc tttgaggatt cgcatattcc cctcaccaaa tggtttatga ccattcacct
     6781 gatgtgctca tcaaagaagg gcatcagcgc ccatcaattg catcgcatgc ttggcgtcac
     6841 ctacaaaacg gcatggttca tggcgcatcg catccgacat gcgatgacgc aattgatggg
     6901 cgcaactccc ctctcaggga ttgttgaagc ggatgagacg tatgtgggcg ggaagcgcat
     6961 cggtgcgggt atgggctatc gggatcataa agtacctgta ttcgctctcg tgcaacgtgg
     7021 gggcgaagtc cgatctatgg tgatgcctcg cgtcacggcg aacacgctca gggctgcgat
     7081 tagaaccaat gtgaagccca ctacgcatgt catgaccgat ggggccaccg tctataccaa
     7141 cgtgtctaac gatgtcgcct cgcatgagac ggtcaatcat tacgagaaag aatatgtgcg
     7201 cggcaacgtc cacacgaaca cgattgaagg ctatttcagc ctgctcaagc gtgggatcac
     7261 cggcacgtat caccacgttg cggagaaaca cttgcaccgt tatctggcgg aatttgattt
     7321 ccgttacaac gcacgcaagg ttgaagattc ggtgcgcacg ttctcggcga tccagggcat
     7381 tgaagggaag cggttgcagt accgatgact taccgagaag agggcttctt tgaagccttt
     7441 ccttttacgg tggaggcctt tttcgaggaa ggcttggcgg taagtagcag cttgagagct
     7501 tcctcaaatt ggaggggact cagagaaacg gggttttcct tcggcattcc acgattgtac
     7561 atggatcact ccagcgcttg caaaagagta ttagagcgtt atagtatttg tgggaagtga
     7621 ctagccggta cttcgcgcca tcacactagc aactaccgcc gcaacgcgta atacttgcta
     7681 gggatgggtc gtagagagcc cttgagcagc cattgcactg gccgtttggg ggcttttctt
     7741 ttagccatac gccttcctcc tttctccaac cagcggggga ttccgctgtg ccaggcagta
     7801 atccccgtca ctgccttgga gtcattcaga aggcttacgc gaagcccgta ctagtcactc
     7861 cccggtttat ttgagcatct ctactgtatc gccctccctt gaaagcctac cggccttcac
     7921 tagccgagta attgcagtcc tcatattgtt cccgtaacgg cccatctttt ctttcatgcc
     7981 cttctcttct agaatggctc gcagcttgcg aatacctatt ggtgcatcct tttcgctcac
     8041 caccatcatc accgcatcag taagcggcaa cgatgaaaac ggaagattca tcggcttcga
     8101 tggaacgcta ggccccccac atcgcggaca gtatttatgc gccttcatct gccaggaccg
     8161 cagatcgtag tccagggcgg taacgcgctc ttgaagggcc ttgacggttg cgcttaattc
     8221 ctcaatgctc tgcgtctgct ccatgttcat tccttctcgc ccgaaggcga cggttcggac
     8281 tataccatga gccgatagac ccatgcaact cagtctgttg gacaaattca atgtccgaca
     8341 ggctaaagtt atctgtggat aacgttcatt gacagaatgt aacctgcgcg gcctacagga
     8401 gaaatcctat cccgaatcat ttgggtgcgt gaagtatata atcacggaga taacgagaga
     8461 ccgccccctc cgaacgacta tggcgaatag atcttggaat ggccgtcagg gagagtggac
     8521 agagcactga ttgatgcggg atgcgtggaa ggaaaacgca gggatggttc aaaaacaggt
     8581 acgactgagg cgccttgcct cccctcacgc gtcgatgaat cagaccgcca aaccgatcgt
     8641 ctgtttgatt tcgcttcgca aggtctcctg ctgattctgg acccaagaat cgagctgcgc
     8701 aaaatgatgc gccagcggtc cggtgaaggg aggcaccagg acatcggcgc gctccttcaa
     8761 ccacccttcc tcctcgg
//
LOCUS       DAOQPD010000108         8577 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_4493_length_8577_cov_22.269772, whole genome shotgun sequence.
ACCESSION   DAOQPD010000108 DAOQPD010000000
VERSION     DAOQPD010000108.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 8577)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8577)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8577
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4493_length_8577_cov_22.269772"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..257
                     /locus_tag="PK063_17190"
     CDS             <1..257
                     /locus_tag="PK063_17190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HMZ98840.1"
                     /translation="IKGFCLTKYSVGFPLFSKISVKGDDKHPLYRYLTEQSPFPGEVE
                     WNFQKYLIDRSGNVVARYKHGTKPLAQEIVKDVERFLAKG"
     gene            complement(264..539)
                     /locus_tag="PK063_17195"
     CDS             complement(264..539)
                     /locus_tag="PK063_17195"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98841.1"
                     /translation="MKETDLEKLTLLYERFCDVCLVEKEVWTEIYMPRTFKDGTAVRT
                     NIQDRYQVMIDDQGVEDALEANIPLGKAALAAAIQEYREHISFEKQS"
     gene            complement(626..1285)
                     /locus_tag="PK063_17200"
     CDS             complement(626..1285)
                     /locus_tag="PK063_17200"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98842.1"
                     /translation="MVAREGTRFSFPLALALCVTSILGWWQTGAEGRDLMVPKEQATT
                     EFEPTEMPSLDVQQKGVPQSLFTWIKMARGYEVEWDTFGRKGWFTQDPRLKPIAPGTT
                     VFTPDTPAVYIVFEVAPLEDPAQFAAQVFAIGADGKTGDAVIVQDSLEVPGHERYGFL
                     ELKKPSSQWPQGKYVVKIYITSLGQQPFHAVNQVGTMRFAVTDQPSADVPPVVPGSPA
                     R"
     gene            1468..2892
                     /locus_tag="PK063_17205"
     CDS             1468..2892
                     /locus_tag="PK063_17205"
                     /inference="COORDINATES: protein motif:HMM:NF019310.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HMZ98843.1"
                     /translation="MNHPTTAAPPSLSQPVLLPNETETAEHEAKASSRQYGIRDAACQ
                     AAAQGGGENYFSAFALLLHASPFHIAILSALPQLVGVVAQLASVKVLRYLRLPRRLLI
                     AGGRAQAFCWLPILSLPLIDPQHGPWLLIGCAMLYFGFGHVTAPVWNSLLVDVAEADS
                     RGAYFAQRARTTALTSFLALGLAGAILTLGQRWDMSWIGFLVIFLGAAAARMGATRCQ
                     THVSRLMPVHQLDAPHGFRHFLANTASRDFRRFLLFSGLMHFAVLLSGPFFVIYLLRD
                     LHWSYLEYAGWMASSISAQFLTLGPWGRIGDRYGNKALLALTASAVPFLPMGYLLSEH
                     YLFLLTVNFFGGVIWAGLSLGLQNYVFDSLQPEERTRGVALANAMNAVGWGLGALTGS
                     WLATQMPTELSIGFWHLTPASNLPFLFCLSGVLRLAIAMSLLRTFAEPRRIASPPQGH
                     LVWELPVLKSLMTLMPWRNPRVAP"
     gene            complement(2917..3123)
                     /locus_tag="PK063_17210"
     CDS             complement(2917..3123)
                     /locus_tag="PK063_17210"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98844.1"
                     /translation="MGQTNSSAAARVSGLVGIIVAAMVLVVGCASDKPKPMAQPSPEQ
                     VKGNADRAFDRLKQEEGERRPSGM"
     gene            3285..3734
                     /locus_tag="PK063_17215"
     CDS             3285..3734
                     /locus_tag="PK063_17215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HMZ98845.1"
                     /translation="MSLHDRLSEDLKSAMKSRDQLRMDVIRMIKAAVQYKEVELKQDL
                     DDAGMSRIMTTLIKQRREAAEQFEKGNRQDLAAKERQEISIIEGYLPAAVSSDELANI
                     VAQVIKESGASSLKDMGQVMKAVMARLAGQSVDGKVVSDLVKTALQR"
     gene            3892..4539
                     /locus_tag="PK063_17220"
     CDS             3892..4539
                     /locus_tag="PK063_17220"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ98846.1"
                     /translation="MSILIVDDSPDQQLLLKTILNKAGQHDLLIADSATSAYDQLGIQ
                     QAPSQEGPHAVDLILMDFLMPGIDGVAATRHIKSLDTLRDIPVIVVTAKTALGDLQAA
                     FAAGAMDYITKPVNSVELLARVNSALMLKKEMDCRKNRELELRRSNEDLQRALREVKV
                     LKGLVPICASCKKIRNDQGFWQQLEEYIQQHSEAEFSHGLCTPCIKKHYPGVYPD"
     gene            4584..5588
                     /locus_tag="PK063_17225"
     CDS             4584..5588
                     /locus_tag="PK063_17225"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009975 - cyclase activity [Evidence IEA];
                     GO_process: GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HMZ98847.1"
                     /translation="MGILIVDDSTDDRLLIQSILANAGYEETFVAESAAAAFRLLGLD
                     GMRQMAGRVDLILMDIVMPSTNGIEACRQIKAVERYRDIPIIMVTVKTDPVDLQLAFA
                     AGAIDYVAKPISKIELLTRVRCVLRLVHEIERRRAREQELLEVMRQLQEANQMLLRLS
                     CLDGLTGITNRRQFDDFLDQEWRRAARESTPLSLIMLDIDFFKTYNDSHGHQAGDECL
                     RQVAQLISSHVNRPGDLVARYGGDEFVIVLPGTTVDGAAQVADTLRRKVCEAEMKHPN
                     GDPVTISLGFASTVPSRVAAPTDLIRAADQALYQAKQEGRNRAKQAGVLSLVHHTHKD
                     "
     gene            5678..>6940
                     /locus_tag="PK063_17230"
     CDS             5678..>6940
                     /locus_tag="PK063_17230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ98848.1"
                     /translation="MAKRISQTRRTTGTTPKRTLRTSSRPQTALQREQAARRRAERAL
                     DRASKELQRRVEELQRAKDAADVANRAKSDFLASMSHEIRTPMNAIIGMADLLWDTTL
                     TPEQRKYLRIFRRAGASLLSLINDILDLSKVESGRLDLDSIDFDLSELIDKASEMLAL
                     RANEKGLELVCHLSNDVPCHLIGDPNRLYQILLNLLGNAIKFTEKGSVVMTITNDPDC
                     QTPGAIRFSVTDTGIGVPHDKMTAIFDTFTQAHSTIARRYGGTGLGLSISQQLAALMG
                     GKIWVESTLGKGSTFHCLVRLGVQAAPAPSKGAGALNLSGVRCLVVDDYPTNRLILRE
                     TLFAWGATVVEAESGEQAMEVLESALTSQTSFDLLLLDCRMPGMDGFEVIERIHADPR
                     LRNLTIIMLASDRWADDIAKTYDLGLGGY"
     assembly_gap    6941..7040
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <7041..7310
                     /locus_tag="PK063_17235"
     CDS             <7041..7310
                     /locus_tag="PK063_17235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HMZ98849.1"
                     /translation="AKFQNGHYDLILMDMQMPVMDGLTATRTIRRWEQEQGLPAVQIV
                     ALTALALKEESARIFEAGCNAHMTKPLKRTTLLELLSAYEKTHAQ"
     gene            7307..7636
                     /locus_tag="PK063_17240"
     CDS             7307..7636
                     /locus_tag="PK063_17240"
                     /inference="COORDINATES: protein motif:HMM:NF013767.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009927 - histidine phosphotransfer kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hpt domain-containing protein"
                     /protein_id="HMZ98850.1"
                     /translation="MMPPQPEAGQPKIIVHIDPDLEAIVPGFLANRRRDLVTIEACLK
                     QSDLNTIRILGHRMKGDGGGYGFDQISSIGDDLEQAVMVQNGPLIEKQVALLKDFLSR
                     VEVVYTR"
     gene            complement(7780..>8577)
                     /locus_tag="PK063_17245"
     CDS             complement(7780..>8577)
                     /locus_tag="PK063_17245"
                     /inference="COORDINATES: protein motif:HMM:NF024895.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HMZ98851.1"
                     /translation="QPPDVGPRTRDQASQERVVTRDRAGDRVVVDERVVERRREGEVY
                     VAGYGGFTWGHSFSDLEGRGTIAGQNFGGRDLANSGVYGAKIGYFHPGRLNWLGIEVE
                     GFNSTPHIEQGGGLPGSHLRVTTLAFNVIARTKVGCRNRDDVRHRDEVRHRDDGTVVE
                     SDYDRRQWSPLDENLRCPLQLYAGAGPGIFFAETSNQFGRSTDNGRIGLNALAGAKYF
                     MTRNLAVFAEYKFNYAQFDFSQMQGTGAGFNGEYKASHVVGGLALHF"
BASE COUNT         1795 a         2672 c         2302 g         1708 t
ORIGIN      
        1 agatcaaggg gttctgcctc accaaatata gtgtcggctt tcccctcttc agcaagatca
       61 gcgtgaaggg tgacgacaaa catccgctct accgctacct cacggagcag agcccgttcc
      121 ccggcgaagt ggaatggaac tttcagaagt acctgattga tcgttcaggc aacgtcgttg
      181 cccgctacaa gcacggcacg aaaccgctgg cacaggaaat cgtcaaggac gtcgaacggt
      241 ttctcgcgaa aggctaagcg ccgtcaggac tgtttctcga aactgatgtg ctcgcgatac
      301 tcttggatgg ccgcagccaa tgcggccttc ccaagaggaa tgttggcctc cagcgcatcc
      361 tccacgccct gatcgtcgat catcacctga taacgatcct gaatattggt ccgcaccgcc
      421 gtgccgtcct tgaacgtgcg cggcatgtat atttccgtcc acacttcctt ctcgactaaa
      481 cagacatcgc aaaaccgttc atacaacagc gtcaatttct ccagatcggt ttccttcatc
      541 ccctgctcct cgcgataaac aatacattca aagaccgcac gagcccacgc ggcagacgaa
      601 cgttagacta agcaggggaa gatattcaac gggcgggaga acccggcacg acggggggca
      661 catctgcgga aggctggtcg gtcacggcaa atcgcatcgt tcccacttga ttcacggcat
      721 ggaacggttg ctgcccgagc gacgtgatgt agatcttgac cacatacttg ccctgtggcc
      781 actgcgacga aggcttcttc aactccaaaa aaccgtatcg ttcgtggccc ggtacctcga
      841 gactatcctg cacgatcacc gcatcgccgg ttttcccgtc agccccgatg gcaaacacct
      901 gggcggcgaa ctgggccgga tcttcgagcg gggcgacttc gaacacgatg tacacagccg
      961 gcgtatccgg cgtgaagacc gtcgtacccg gcgcgatggg tttcagccgt ggatcctgcg
     1021 tgaaccaccc tttgcggcca aacgtatccc actcgacttc ataaccgcgc gccatcttga
     1081 tccaggtgaa gagtgactgc gggacgcctt tctgctgcac atccagtgac ggcatttcgg
     1141 tgggttcgaa ctccgtggtg gcctgctctt tgggaaccat cagatcgcga ccttcggcgc
     1201 ccgtctgcca ccatcccagg atcgaggtga cacagagagc gagcgccaat gggaaggaga
     1261 accgcgtccc ctcacgggca accaagtctg ctgctccttg tgaaacccgg gcatccatac
     1321 agttatggta cccactgtga gaacaggggg tcaaccggcc tgcgcgattt gatcaaaaca
     1381 gaaggcaacg cggttcgctc tgatataatg cctttcattc aacgcaaaat tcgtaggcat
     1441 cgcgcacttg ttcccgcgca aagtcccatg aatcacccaa cgaccgccgc cccgccctca
     1501 ctttctcagc cagtcctatt gccgaacgag acggaaaccg cggagcacga ggccaaggcg
     1561 agcagccggc aatacggcat ccgggatgcg gcctgccaag ccgcggccca aggcggcggg
     1621 gaaaactatt tctcggcgtt cgccctgttg ttgcacgctt ctccgtttca tatcgccatt
     1681 ctgtccgcgc ttccgcaatt ggtcggagta gtggcacaac tcgcctccgt gaaggtgctt
     1741 cgctatcttc gtctgccacg acgcctgctc atcgccggag gccgggccca ggccttctgc
     1801 tggcttccga tcctgtcgct gccgctgatt gacccgcaac atggcccctg gctgttgatc
     1861 ggctgcgcca tgctctattt cggctttggc catgtcaccg ccccggtctg gaatagtctt
     1921 ttggtcgacg tcgcggaagc cgacagtcgc ggcgcctatt tcgcccagcg tgctcgcaca
     1981 accgcgctca cgagttttct ggcattagga ctggccgggg ccatcctgac gctggggcaa
     2041 cgatgggaca tgagctggat cggcttcctt gtcattttcc tcggcgccgc tgccgcgcgt
     2101 atgggagcca cacgttgcca gactcacgtg tcacggctga tgccggtcca ccagctcgat
     2161 gcgccgcacg gcttccgaca ttttcttgcc aacaccgcca gccgggattt tcgtcgcttc
     2221 ctcttgttct ccgggttgat gcatttcgcg gtgttgctgt cgggaccgtt ttttgtgatc
     2281 tatctcctgc gagaccttca ttggtcctat ctcgaatatg ccggctggat ggcgagcagt
     2341 atctcagctc aatttctcac gctgggcccc tggggtcgaa tcggtgaccg atacggcaac
     2401 aaagccttac tggcgctgac ggcctcggca gtgccgttcc tgccgatggg ctacctgttg
     2461 agcgagcact acctgtttct gttgaccgtc aactttttcg gtggcgtgat ctgggcggga
     2521 ctgtcgctcg gcctgcagaa ttatgtcttc gattcattac aaccggaaga gcgcaccaga
     2581 ggggtcgcgc tggccaatgc catgaatgcg gtgggatggg gactcggcgc actgaccggc
     2641 agttggctgg cgactcagat gcccactgaa ctctcgatcg gcttctggca tctgacgccg
     2701 gcgtcgaacc tgccgttttt gttttgcctc tcgggagtct tgcgacttgc tattgccatg
     2761 agtctgctgc gcacgtttgc tgagccccgg cgcattgcct ctccgccaca aggacatctg
     2821 gtctgggaac tgcccgtcct gaaatccctc atgacgctca tgccctggag aaacccacgc
     2881 gtggcaccct agagggcgca cagcccgaag ccaggcttac atccccgatg gccggcgctc
     2941 tccctcttcc tgtttcaacc ggtcaaacgc acgatccgca ttccctttga cctgctcagg
     3001 tgacggctga gccatcggtt tcggtttgtc gctggcacag cccaccacga gcaccatcgc
     3061 cgcaacaatg ataccgacga gcccgcttac ccgcgccgct gcactgctgt ttgtctgccc
     3121 cattctgagc ctccgtggtt aagtgccaac gctaccgccg attgcattat gggacaggac
     3181 ctcccggcgc tcaatacaaa acgtgcgcgc ctcagccacg ttgactggct ccggtaaagg
     3241 cgttattctc cgcgacgacg catttccctg ctgaaaggaa cccgatgtcg ctgcatgatc
     3301 gcttatccga agacctgaaa tcggccatga agtccagaga ccagctgcgt atggacgtca
     3361 ttcgcatgat caaagccgcc gtgcaatata aggaagtcga actcaaacag gatctcgacg
     3421 atgccggcat gagccggatc atgaccactc tcatcaaaca gcgcagggaa gcggccgagc
     3481 aattcgagaa gggcaatcga caggacttgg ccgcgaaaga acggcaagag atcagcatca
     3541 tcgagggcta ccttcctgcc gcagtctctt ccgacgagct ggcgaatatt gtcgcacagg
     3601 tcatcaaaga atccggtgca tcgtcgctga aggacatggg gcaggtcatg aaagccgtca
     3661 tggctcgtct ggccgggcaa tccgtagacg gcaaagtcgt cagtgacctg gtcaaaaccg
     3721 cccttcaacg ctgatccgcc tcgctgccgg acttaacctc ctcggtcttt tcgccgatac
     3781 tgaatccgac gtacggcggc gaaggggtat gccctcacgc ctctcctcca ttcgtgatgc
     3841 tcccgggaac caggagccgg ctccgccacc tctgcccgac gaggcgatga catgagcatt
     3901 ttgattgtcg atgactcccc tgaccagcaa ctgctgctca agaccattct caataaagca
     3961 ggccagcacg acctgctcat cgcggactct gcgacctcag cctacgacca gctcggcatt
     4021 cagcaggctc cgtcgcagga agggccccat gccgtcgatt tgatcctcat ggattttctc
     4081 atgcccggca tcgacggcgt cgcggcgacg cggcacatca agagcttgga cacattgcgg
     4141 gatattccgg tgatcgtcgt cacagccaag accgccctgg gcgacttgca ggccgccttt
     4201 gccgccgggg cgatggatta cattacgaaa ccggtgaaca gcgtggaatt gcttgcccgg
     4261 gtcaattccg cactcatgct caaaaaggaa atggattgcc gcaaaaatcg cgagctggaa
     4321 cttcgccgga gcaacgaaga cctgcaacgg gcgttgcgcg aagtgaaggt actgaagggc
     4381 ctcgtgccga tctgcgcctc ctgcaagaaa atccgcaatg accaaggctt ctggcaacaa
     4441 ttggaagaat atatccaaca gcattcagag gcggaattca gccacggcct ctgcaccccc
     4501 tgcatcaaaa agcattaccc tggtgtttac ccagactagc tgctagcatc gacctacgac
     4561 atattttcag ggagacactg atcatgggta tcctgatcgt cgatgattcg acagacgatc
     4621 gtctgttgat ccaatccatc ctcgccaatg ccggatacga agagacgttt gtggcagagt
     4681 ccgccgccgc cgcgtttcgt ttgctgggcc tcgacgggat gcgccagatg gccggccgtg
     4741 tggatttgat cctgatggat atcgtcatgc cgtccaccaa tggcatcgaa gcctgccgcc
     4801 agatcaaggc cgtcgagcga taccgggaca tcccgatcat catggtcacc gtcaagaccg
     4861 accccgtcga tctgcaactc gcctttgctg caggcgccat tgattatgtg gcgaagccga
     4921 tcagcaagat tgaactcttg acccgcgtcc gttgcgtgct ccgcctcgtc catgaaatcg
     4981 aacggcgccg ggcacgcgag caggaattgc tcgaggtcat gcgccagttg caggaagcca
     5041 accagatgct gctgcgcctc tcctgccttg acgggcttac cggcatcacc aatcgccggc
     5101 agttcgatga cttcctcgac caggaatggc ggcgcgccgc gcgcgaatcc accccgctgt
     5161 cactcatcat gctggatatc gattttttca aaacctacaa cgacagccat ggccatcagg
     5221 ccggagacga atgcctccgt caggtcgccc agttgatctc cagccacgtc aatcgtcccg
     5281 gcgacttggt cgcacggtac ggcggcgacg aattcgtcat cgtgctgccc ggcacaactg
     5341 tcgacggagc cgcacaagtc gccgataccc tcagacggaa agtctgcgaa gcagagatga
     5401 aacatccgaa cggcgatccg gtcacgatca gcctgggctt cgccagcacc gtgcccagcc
     5461 gcgtcgccgc cccgaccgat ctgatccgcg cggccgacca ggcgctctat caagccaagc
     5521 aggaagggcg caaccgcgcg aaacaagcgg gtgtgctgtc cctcgtccac catacgcata
     5581 aggactgaca gttactcgcc gtcgcgacga tcgtgccggc ttcctctact cgcgatacga
     5641 tatggttatg accatctgaa ggcgaccgga cgacgacatg gcgaaacgca tctcgcaaac
     5701 cagacgcacc acaggcacca ctcctaaacg cacccttcgc accagttccc gtccacagac
     5761 agcactccaa cgtgaacaag ccgcgcgccg gcgtgccgaa cgcgcgcttg atcgcgcctc
     5821 taaggaattg caacgccgcg ttgaggagct gcaacgcgcc aaagatgcgg ccgacgtggc
     5881 caaccgcgca aagagtgatt tcctggccag catgagtcat gaaatcagga cgccgatgaa
     5941 cgccatcatc ggcatggctg atctgttatg ggatacgact ttgaccccgg agcaacggaa
     6001 gtatctccgg atctttcgac gcgcgggcgc aagcctgctg agtctgatca acgacattct
     6061 cgatttgtca aaagttgaat ccggccggct cgatctcgat agcatagact tcgacctctc
     6121 ggaactcatc gacaaagcga gcgagatgct ggcgctccgc gccaacgaaa aaggcctcga
     6181 actggtctgt cacctgtcga acgatgtgcc gtgccacctc atcggtgatc ccaaccgcct
     6241 ctaccagatt ctgctcaacc tgctgggaaa cgcgatcaag ttcacggaga agggatcggt
     6301 ggtcatgacc atcaccaacg atccggactg ccagacaccc ggcgccatcc gattctcggt
     6361 gactgatacg ggcatcgggg ttccccacga caaaatgaca gccatcttcg acacctttac
     6421 gcaggcgcac agcacgatcg cccgccgcta tgggggcacc gggctgggat tatccatttc
     6481 acagcaactg gccgcactca tgggcggaaa gatttgggtc gagagcaccc tcggcaaggg
     6541 cagcacgttc cattgcctcg ttcggttggg cgtacaagct gcgccggcac cttcgaaagg
     6601 cgcgggggcc ctgaacctga gcggtgtgcg ctgtctcgtc gtggatgatt acccgacaaa
     6661 ccgtttgatt ctgcgggaaa cgctctttgc ctggggcgcc accgtggtgg aagccgagag
     6721 cggagagcag gccatggagg tgcttgaaag cgcgctcacc tcgcagacgt ccttcgatct
     6781 ccttttgttg gactgccgca tgccgggaat ggatggattc gaggtcatcg aacgtatcca
     6841 tgccgatccc cgccttcgca acttgacgat catcatgctg gcctccgacc gatgggccga
     6901 tgacatcgcg aagacctacg acttgggact gggcggatac nnnnnnnnnn nnnnnnnnnn
     6961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7021 nnnnnnnnnn nnnnnnnnnn gccaaatttc aaaacggtca ctatgacctg attttgatgg
     7081 atatgcagat gccggtgatg gacggactga ctgccacacg cacgatccgt cgctgggaac
     7141 aggaacaggg gcttccggcc gtccaaatcg tcgccctgac cgccctggcg ctgaaggaag
     7201 aatcggcgag aatttttgaa gccggatgta acgcccacat gaccaagccg ctcaaacgaa
     7261 cgacgctgct ggaactccta tccgcctacg agaagaccca cgcgcaatga tgccaccgca
     7321 acctgaggca ggacagccta agatcatcgt ccatatcgat ccggatctcg aagccatcgt
     7381 cccaggcttc ctcgccaacc gccggcgtga tctcgtgacg atcgaggcct gcctgaagca
     7441 gagcgatttg aatacgattc gcatattggg ccatcggatg aaaggcgacg gcggcgggta
     7501 cgggttcgat cagatcagca gcatcgggga cgatctggag caagccgtga tggtacaaaa
     7561 cggaccgttg atcgaaaaac aagtcgcgtt actgaaagat ttcttgagtc gcgtggaagt
     7621 cgtctataca cgctagatcc tcgcacctgg cacctccttc ccctctacac gaagccccgt
     7681 ccctgacgac cgtgagaagt tacgcgcaga gccaggcggc gcgggctcaa cggtcatgtc
     7741 ggtgaccgct gaaccctgga gcgtcacgcg gcaatcatgt cagaagtgaa gtgccaatcc
     7801 tccaaccaca tggctcgctt tgtattcgcc gttgaacccc gctcccgtgc cctgcatctg
     7861 cgagaagtcg aactgcgcat agttgaattt gtactctgca aagaccgcaa gatttcgagt
     7921 catgaaatac ttcgctcctg ccagcgcatt caagccgatc cgcccgttgt cagtactgcg
     7981 gccgaattga ttcgacgttt cggcaaagaa aattccggga ccagcaccgg catacagttg
     8041 caaggggcag cggagatttt cgtccaatgg cgaccactgt ctccgatcgt agtcggattc
     8101 caccaccgtg ccgtcatcgc gatgcctgac ttcatcccga tggcgcacgt catcgcgatt
     8161 tctgcaaccg accttcgttc gggcaatcac attaaacgcc agcgttgtca cccgaaggtg
     8221 tgatcccggc aaccctccgc cctgctcgat gtgaggcgtc gaattgaacc cttccacctc
     8281 gatgccgagc cagttcaacc gacctggatg aaaatagccg atcttcgcgc catacactcc
     8341 ggaattcgcc agatcacggc ctccgaagtt ctgacccgcg atagtgcccc ggccttcgag
     8401 atccgagaag ctatgtcccc acgtgaaacc tccataccct gccacataaa cttcgccttc
     8461 cctgcggcgc tccaccaccc gctcatcgac gaccacccgg tcacccgcgc gatcccttgt
     8521 gacgactcgt tcttgagatg cctgatcgcg cgtccgtgga ccgacgtccg gtggttg
//
LOCUS       DAOQPD010000109         8366 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_4670_length_8366_cov_16.739622, whole genome shotgun sequence.
ACCESSION   DAOQPD010000109 DAOQPD010000000
VERSION     DAOQPD010000109.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 8366)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8366)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8366
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4670_length_8366_cov_16.739622"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..679)
                     /locus_tag="PK063_17250"
     CDS             complement(<1..679)
                     /locus_tag="PK063_17250"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98852.1"
                     /translation="MWQRMAALSLALLSGCVSTGEYQDLETKYQHQLAVKEVMETEHD
                     ELSQRVDNVSQVYRHVAQEQMGLKAQAEKLQGDILTVKGVVKDTQNQYESQRAQFAQQ
                     AQQLSGVDARLQNIAGKIETLTETTVALANRFERVELSIGKLGKSLQARGGAPDVQKT
                     RVQLGEGKSGSAPKTEPVAKAGSPNMEGSVGAGGSGVEPSGTSLAVAPSPVATTTVPA
                     KLDVPMPV"
     gene            complement(724..1368)
                     /locus_tag="PK063_17255"
     CDS             complement(724..1368)
                     /locus_tag="PK063_17255"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98853.1"
                     /translation="MAHGVDAERQLGMVRREGQSLRSASPTNGRRPDRAEENKRRLED
                     PNSVLLLPQTKAGMACVSMLYMFDKVIHRLRRAAGSQLSIEQVRNELARVEQWVARAK
                     VILRELGVGEFELLPQDPYPDLKERSVKAAWRNARVITPRVGDTVRLVPVIRALDNAL
                     NSIRLRAEDLTPYVKHFQAVDELVVALHDVIGHVARVTVTEYEPRGAVKAFLNQ"
     gene            complement(1384..2013)
                     /locus_tag="PK063_17260"
     CDS             complement(1384..2013)
                     /locus_tag="PK063_17260"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98854.1"
                     /translation="MARVIRMDPGHSAYLLWADSIGRYAILPHQYADRQYKVRDSLMG
                     AVYKVGDEFPMLSQRSMHYFRRIAELVLAPVLADDHVHIKRVATAQAASFVKIAVETY
                     RTGEDVIATCKPLLYEFRTYTSRTIALVKYHMEVEAYIREALAPAPSRSVRRVDVYRE
                     EHQARVIVERGTIAQFLGRKGMNAAVASKLTGYGLVLVDEADLGKTARA"
     gene            2231..3418
                     /locus_tag="PK063_17265"
     CDS             2231..3418
                     /locus_tag="PK063_17265"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98855.1"
                     /translation="MVLLVLVTLVSCAPVFTPTTLQNFKESRETSSTTAVERPRLALS
                     PHSDGLGWTVRVTQTVEEKNRIRREEVWGGYTYERRLNLVTMVGGGLLCAPNLLLNTL
                     FSMGTPNQPGWSSPWQYCLAAAGYDVPGRADTRTRIADDLDPQVQTVTRIIVDGDLRL
                     TFAADGRDRIGIAVPVSKDSQGTHIRLRWLAMALREQGVNPADVPDGTVEISYSPTVG
                     NPGPTTQLPIDGHVLTAMLQHDLAVLPQDRWPKQPRLRLAVNNDWGHEQSQLIVDRLI
                     GRMKERGLPLVVRNERYRKLVPVQVRQLAPFFNDERQPSAGMGTGANLLVSIDIASAS
                     DQGLLLTTTLVSVETAQVLAQFVLECPINAVAPTAETLAAVVTDLVLPHGPTLTRGWF
                     VTP"
     gene            3415..4539
                     /locus_tag="PK063_17270"
     CDS             3415..4539
                     /locus_tag="PK063_17270"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98856.1"
                     /translation="MTRYGTFLICFLATSAVGCSSLILSNTPVQGENTSTREIARTPI
                     DVPEVTLTPHHDQQRLTIRVTQRSQITLETDTPMQAEARRYVFSPTAPLAGAVHCPVL
                     TVAYVISAGHLGSQSLAPACRRLLMQEPLAGSPRVAAEIEHRYETRTTTEPVRYATLR
                     VAWDDAIHPPLVYDVNPDGEVSIPQHALRSGTERDPSTLPTLSILVDNRVLWTHRLTP
                     SEMTPSGPLPDEPHTAGTSWPPIVALVLEPLDGAAPPALRAWGRLVTQALLERHICVV
                     APITFAKDLQDELLLHQSGRISDQTAVHFGKWIPATVALTIRNGAANQGIAILEFVDI
                     QRAERIRYDVLRYSSDWKEDAQMLKAYMQTVFPKGYQSCS"
     assembly_gap    4592..4691
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<4692..>8366)
                     /locus_tag="PK063_17275"
     CDS             complement(<4692..>8366)
                     /locus_tag="PK063_17275"
                     /inference="COORDINATES: protein motif:HMM:NF019530.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraG N-terminal
                     domain-containing protein"
                     /protein_id="HMZ98857.1"
                     /translation="DPATGDEEGLTEDIRANLLLSVGQSARDMINNVLLIHAWKNAES
                     ADAKRRAATADTVLLQQQAIQKDLKFQSYSKSYVAQKVVPLLRTIVEGVVYIMTPFLL
                     VLAISPGMSRLMGTYWRLFMWLQTWSPLYAVLNFVMFWEARSRLGAILSSNGVGQSVN
                     YATLDRINEHVAMLNSTAADYVWLVPAIGFGLMWGGSQVLGSILAGSRTAETVAGQVG
                     GQFSRGLGANLEEGPSYRHEQRGAQFGEMIGHDVEPQMTVPTGQGGFRVDSQSGTSEI
                     HDSQGGITSIGANGIQNYKGPEGQYSMDSKGHLLSGVFRHKMFDPQSGKQVDAQTSVF
                     GSMVEHRFDTMGEDGSRKSVLVQENQDTGELVARTEQSVRKGLSETRTIAEDGSQSFA
                     RSGNVPLFLEVAGETRPDAGFVQMMGERGPGERVDTLTQSTFQSTMGAKQSYTGRLVE
                     RDGQFHFLATEGGAVRGFDNKDTEAGVHRESFVSPDGSNYFVETGQAEQMVLGKDGVT
                     RPMEGYVRAFGSVDRSDPVHPRDIYSSYSLTSDEGGHTHTVTGTLGTDASGRQFLVEA
                     TEHFESGTSGVAHDTHTVGSYTLSGTFTALSHGEANQPGVPTAFFGSAIDNSKPGSPA
                     FQANALLYDGQVSFFDGREGGTKSISGERNLVDGTHLSGQFTQLNVMGQDGHQVEMFH
                     GYAQQPGAPARDVTGLIDNGSLVSFKGASGNEFRDVIERTDSGDLQSIGAQETYSAPG
                     GTHSLSNFQGVTVNPQGDAFKRSSTNLDGVSVYSDQMRGSRQMTVEFEQSLRGYNNEV
                     QSIDKESGWRRINDGHRDMDVYANLYYGPTSSETGERKLLGGTITNVTDNTYSTFMKD
                     GEGNEVWGIARSLEDPNSGAMSGSIDQTVKVVAAKNGAIDTQVLGPMKDDGGQREVLY
                     HSVLGGLDSQYYNNERKSGIFTVPDPMHPGQTKELQGTFYYSPQSGQLIASEVTDLQT
                     GKIGQYRTDAQGQEHFQVVEYSQSPDGASVIANTKELSKNEYAAHGFAVNDVLDGSGN
                     VLSSSGHKGSDFHDFNRVQFHHDSGANLTITQMAFAAKGTDITNPTQTDEAIAYGLEF
                     GRIGMDGASRYLILKGRMGKFGGGGVGGTPVQPGGGPVPNGPGGGGGPSGLLDSHQNM
                     GAWWKEYSGVMDNAISFARSSVEHLEKTGRAQSMSPEELQNFAANAAYNAVRTSALGM
                     MGEEASNAFGTMPKWQEGQES"
BASE COUNT         1745 a         2646 c         2011 g         1864 t
ORIGIN      
        1 gaacgggcat cggcacatcc agtttggcag ggacagtggt cgtcgccact ggacttggag
       61 cgaccgctag gctcgtcccg ctcggttcaa cacccgagcc cccagcgcct acgctcccct
      121 ccatattcgg actgccagcc ttggcgacag gttccgtttt gggagcactt cctgacttac
      181 cctcacccaa ctggacacgc gttttctgga cgtcgggagc accacctcta gcctgcaagg
      241 acttcccaag tttcccaatc gacagttcaa cacgttcgaa gcgattggct aaggcgaccg
      301 tcgtttcggt gagggtttcg atcttccccg caatattttg caggcgcgca tcgaccccgg
      361 acagttgttg cgcctgctgc gcaaactgcg cccgctggga ctcgtactga ttctgggtgt
      421 ctttcaccac ccccttcacg gtcaggatgt ccccctgcag tttttccgct tgggccttta
      481 gtcccatctg ctcttgcgca acatgccgat acacctggga tacgttgtcg actcgctggg
      541 acagctcgtc gtgctcggtc tccatgactt ccttcaccgc gagttgatgc tggtacttgg
      601 tttccaaatc ctgatattcc ccggtgctga cgcaaccgga caacagtgcg agactaaggg
      661 ctgccatgcg ttgccacata ccgtgctcct ttcatacgag aggggtgact acctcccttt
      721 tccctattgg ttcagaaatg ctttcaccgc gccccgcggc tcatactctg tcaccgtcac
      781 gcgagcgaca tgcccgatga catcgtgcaa ggccactaca agctcatcga cggcctgaaa
      841 atgtttcaca tacggagtga gatcttccgc tcggagacga atgctattga gcgcgttatc
      901 tagggcgcga atcaccggca ccagtctcac cgtgtctccg acgcggggcg taatgacacg
      961 cgcattgcgc cacgccgcct tcacgctccg ttcttttagg tcgggatatg ggtcttgagg
     1021 gagcaactcg aactccccca ctccaagctc tcgcaagatc acctttgccc gcgccaccca
     1081 ttgctccaca cgagccaact cgttgcgcac ttgctcaatg gagagctgag atcctgctgc
     1141 ccgccgaaga cgatgaatta ccttgtcgaa catgtacagc atggagacac aggccatccc
     1201 cgcctttgtt tgtggtaaaa ggagcaccga attcggatct tccagccgcc gcttgttctc
     1261 ctccgcccga tcgggccttc gtccattcgt cggagacgcg ctccgaagag actggccctc
     1321 gcgccgtacc atccccagtt gtcgctctgc gtccacccca tgagccatgc ctcacctcct
     1381 cgattacgcc cgagctgtct tccccagatc cgcttcgtcc acgagcacca gtccataccc
     1441 ggtcaatttg ctggccaccg cagcattcat ccccttgcga ccaagaaact gtgcgatcgt
     1501 gccccgttca acaatgactc gcgcctgatg ttcttcccga tacacgtcca ctcgtcgcac
     1561 tgaccgactc ggggccggcg ctaatgcctc gcgaatgtag gcttccacct ccatgtgata
     1621 cttcacgagt gcgatcgtgc gggatgtgta ggtccggaac tcgtacaaca gaggcttgca
     1681 ggtcgcgatg acatcttccc ccgtgcgata ggtctcgacc gcaatcttca caaacgacgc
     1741 ggcttgagcc gtcgccacac gcttgatgtg cacatggtcg tccgccaaca ccggagccag
     1801 cactaactcc gcaatacgcc ggaagtagtg catcgatcgc tgcgacagca tcggaaactc
     1861 gtcaccgacc ttgtacacag ctcccatcaa tgagtcgcgt accttgtact gacggtcggc
     1921 atactgatgc ggcaagatgg catacctccc gatggaatcc gcccacagca gatatgcgct
     1981 gtgccccgga tccatccgaa tgacccgagc catcactaag tctcccacct gcaccattcg
     2041 tcactcgcct gtgctatagt ttttcgaccc gtatacgcac ctgccacatg cgtgtagttc
     2101 gagactcggt ctcacaacta tgcccaacag gtattaccgg atcactccca ctccgcttct
     2161 atcctcatct agagagaaga tccgctctct tgcgtacctt gcttggcagt ggtctagtcg
     2221 gacgatcagc gtggtcctcc tcgtgctcgt caccttggta tcttgtgccc ccgtcttcac
     2281 gccgaccact ttgcagaact tcaaagaatc gcgtgaaacc agctcaacga cggctgtaga
     2341 acgtcctcga ttggcactat caccccacag tgatggcctg ggatggacgg tgagagtcac
     2401 ccaaaccgtt gaggagaaga atcggatcag gcgagaagaa gtctggggag gatataccta
     2461 tgaacgtcgg ctcaatcttg tcacgatggt gggaggggga ctactctgtg ctccaaatct
     2521 cctgttgaat accctctttt ccatgggaac accaaaccag cccggatgga gttcaccatg
     2581 gcaatactgc ctggccgccg ccggatatga cgtgcctggc cgcgccgata cccgaactcg
     2641 gatcgctgat gacctcgatc cccaggttca gactgttacg cggataattg tggacggtga
     2701 ccttcggctc acttttgccg ccgatggacg ggaccgcatt gggattgccg tccctgtaag
     2761 taaagattct caagggacgc acatccgcct tcgatggctt gcaatggctt tacgggaaca
     2821 gggcgtgaat cctgccgacg tccctgacgg gaccgtcgag atttcctaca gtccaactgt
     2881 cggcaacccc ggcccgacca cacagttgcc gatcgacggg cacgtactca ccgccatgct
     2941 gcagcacgat ctcgcggtgc tcccccaaga tcgctggccg aagcagcctc gcctcaggct
     3001 ggcggtcaac aatgactggg gacacgaaca gtcccagttg atagtagaca ggcttattgg
     3061 ccgtatgaag gagcgcggcc ttccgctggt cgtccgaaac gaacggtatc ggaaactagt
     3121 tcctgtccag gtccggcaac tcgctccgtt ctttaatgat gagcgacaac cgtcagccgg
     3181 catgggcacc ggagcaaatc tgctcgtatc catcgacatc gcctctgctt cagatcaggg
     3241 gctgctgctc accacgactc ttgtctctgt tgagaccgca caagtgctgg ctcagtttgt
     3301 cctcgaatgt ccgatcaacg ccgtcgcgcc aacggccgaa actctggcgg cagttgtcac
     3361 cgatctcgtc ctgccccatg gtcccactct cacacgggga tggttcgtca caccatgaca
     3421 cgatatggca cattcctcat ctgcttcctc gccaccagtg cggtcggctg ttcgtctctc
     3481 atactctcca acaccccggt gcagggagaa aatacctcga ctcgagaaat cgcgcgcact
     3541 ccgatcgatg taccagaggt tacccttaca ccccatcacg atcagcaacg cctcaccatt
     3601 cgcgtgacac aacgctccca aatcaccctc gagacggaca cgccgatgca ggccgaggca
     3661 cgacgctatg tgttttcgcc taccgctccc cttgccggcg ctgttcattg tccggtactg
     3721 actgttgcct acgtgatttc agccggacac ctaggctcac aatctcttgc tcccgcctgc
     3781 cgacggctcc tgatgcagga gcctcttgcc ggatcaccgc gggttgccgc cgagatcgaa
     3841 caccgctacg agacacgcac cacaacagag cccgtgcgct acgccacact gagagtggca
     3901 tgggacgatg cgatacatcc gccactggtc tatgacgtga atcccgatgg agaggtgtcc
     3961 attcctcaac acgcactccg ttcggggacg gagcgcgacc cgtcgacgct tcccacactg
     4021 tctatcctcg tcgacaatcg cgtcctctgg actcatcgcc ttacccctag cgagatgaca
     4081 ccaagtggcc cattgcccga cgaaccgcac acggcaggta cgagctggcc accgatcgtc
     4141 gcactcgtcc tcgaaccgct cgatggcgct gcaccacctg cgttgagagc atggggacgt
     4201 ttggtgacac aggctttatt ggaacgccac atctgtgtgg tcgcaccaat aaccttcgcg
     4261 aaagacttac aggatgagct gctactccac caatccgggc ggatcagtga ccagacggct
     4321 gttcactttg gcaaatggat acccgccact gtggcgctca ccatcagaaa cggggccgcc
     4381 aatcagggga tagctattct agaatttgtg gatattcaga gggcggaacg aatcagatac
     4441 gacgtcctac ggtatagtag cgactggaaa gaggatgcgc agatgctgaa ggcctatatg
     4501 caaacggtct tccccaaagg atatcaatcc tgctcatagc aatctcactt cgcatcctgt
     4561 acctcaagca cgcaatcacc atacacagtg annnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4681 nnnnnnnnnn ncgactcttg gccttcctgc catttaggca tagtcccaaa cgcattcgac
     4741 gcctcttcac ccatcatgcc gagggccgat gtacgcaccg cattataagc ggcattggca
     4801 gcaaagttct gtaattcttc gggagacatg ctttgtgcac gcccggtctt ttctaaatgt
     4861 tcgacagaac tgcgcgcaaa cgagatagca ttatccatca ctccggaata ttctttccac
     4921 caggcgccca tattttgatg cgagtccaaa agaccgctcg gtcccccacc tccaccaggg
     4981 ccattcggca cgggtccacc acctggctga accggtgttc ctccaacccc tcccccacca
     5041 aatttcccca ttcgtccttt gaggatcaaa tatcgcgaag ccccatccat tccgatccga
     5101 ccaaattcaa gcccataagc aatcgcctcg tccgtctgcg tagggtttgt aatatcggtg
     5161 cctttggccg caaacgccat ttgtgtaatc gtcagattcg ccccactgtc atgatgaaat
     5221 tgcacacgat tgaagtcatg aaaatcggag cctttgtgac cggacgaact cagcacattc
     5281 ccgctaccat caagtacatc gttaaccgca aatccatgtg ccgcatactc attcttcgat
     5341 agctccttcg tatttgcaat cacgctcgcc ccatcgggcg actgtgaata ctccactacc
     5401 tggaagtgtt cttgcccttg tgcatcagta cggtactggc cgattttccc tgtttgcaag
     5461 tccgttactt ctgacgcaat taactggcca gactgaggac tatagtagaa cgtcccctgc
     5521 agctccttgg tctgcccggg atgcatagga tcaggcacgg tgaaaatgcc ggatttacgc
     5581 tcattgttat agtactgtga gtccaatccg cccaacaccg aatgatacaa gacttcgcgc
     5641 tggccgccat catccttcat aggaccaagg acttgtgtgt ctatcgctcc gtttttcgcc
     5701 gccacgacct tcacggtctg atcgatagag ccgctcatag ccccgctgtt tggatcctcc
     5761 agtgacctgg cgattcccca cacctcgttg ccttccccat ctttcataaa ggtggaatag
     5821 gtgttatcgg tcacgttggt aatcgtcccg cccagtagct tgcgctcgcc agtctcacta
     5881 ctggtcgggc cgtagtagag attggcgtat acatccatat cgcgatgccc gtcattgatc
     5941 cgacgccagc ctgactcttt atcgatcgac tgtacctcgt tgttgtaccc acgcagggac
     6001 tgctcgaact cgacggtcat ttggcgcgat cctctcatct gatcgctata cacactcacc
     6061 ccgtccaggt ttgtggatga tcttttgaag gcgtccccct gaggattaac ggttactccc
     6121 tgaaaatttg atagcgagtg agttcctcca ggagcactat atgtctcctg agcgccgata
     6181 gattgaagat ctccagaatc agttcgttca ataacatctc ggaactcgtt tcctgaggct
     6241 cctttaaacg agacgagact accgttatca atcagccctg tgacatcgcg ggccggagcc
     6301 cccggttgct gcgcataccc atgaaacatc tcaacttgat gtccatcttg tcccatcaca
     6361 tttaactgcg tgaactgccc agacaaatga gtgccatcca ccagattacg ttccccggaa
     6421 atactcttgg tacctccctc ccgcccgtca aaaaagctca cctggccgtc gtataacagc
     6481 gcattggctt gaaacgccgg agaacctggc ttgctattgt cgatggcaga gccgaagaag
     6541 gctgtcggca ctcctggttg attggcttcc ccatgactca gagccgtgaa cgtgccgctc
     6601 agggtgtagg aaccgaccgt gtgggtgtcg tgggcaacac cgctcgtgcc tgactcaaaa
     6661 tgttccgtgg cttccaccaa gaactgtcgt cctgatgcat cggtgcccaa tgttcctgtc
     6721 actgtgtgcg tgtgaccacc ctcatcacta gtcagactgt aactggaata gatgtctcgc
     6781 ggatgcaccg ggtccgagcg atcgactgac ccaaacgccc tgacatatcc ctccatcggc
     6841 cgagtcaccc catctttccc taagaccatc tgttccgctt gcccagtctc cacaaaataa
     6901 ttggaaccgt caggggaaac gaacgattcc ctgtggacgc cggcctccgt atccttgttg
     6961 tcaaatcctc ggacggcccc gccctcggtc gccagaaaat gaaactgtcc atcgcgttct
     7021 accagtcgcc cggtatacga ttgtttggca cccatcgtgc tctgaaatgt cgactgtgtg
     7081 agggtgtcta cccgctcgcc tggcccacgc tcacccatca tctggacaaa tccggcatcg
     7141 ggacgtgtct cgcccgcgac ttccaaaaac aacggcacat tccccgatcg tgcaaaactt
     7201 tgactaccgt cttcagcaat cgtacgcgtc tcggacaggc ctttccgaac ggattgttcc
     7261 gtgcgcgcca ctaattctcc ggtatcctga ttttcctgca caagcacgct cttcctggag
     7321 ccatcctccc ccatcgtatc gaagcgatgc tccaccatcg aaccaaacac cgaggtttgt
     7381 gcatcgacct gcttcccgga ctgtggatca aacatcttgt gacggaacac cccactcagc
     7441 agatgcccct ttgaatccat tgaatactgt ccttctggcc ccttgtagtt ctgaatgccg
     7501 ttcgcgccaa tactggtgat gccgccctgg gagtcgtgga tctcactcgt gccggattga
     7561 ctatccacac gaaacccacc ctgaccagtc ggcacagtca tctgtggttc gacgtcatgg
     7621 ccgatcatct cgccgaactg ggccccacgc tgttcgtgtc gataggacgg gccttcctcc
     7681 aaattggcac caagcccacg tgagaactgt cctcccactt gccccgcgac ggtttccgca
     7741 gtccgcgatc ctgccaggat cgatcccaac acctggcttc cgccccacat cagaccgaaa
     7801 ccgatcgctg gcacgagcca cacataatct gcggctgtgg aattcagcat ggcgacatgt
     7861 tcattgattc tgtctaacgt tgcatagttg acggattggc caaccccgtt tgagctcagg
     7921 atcgcgccga gccggcttcg cgcttcccaa aacatgacaa aattcagcac ggcatacaga
     7981 ggcgaccagg tctggagcca catgaacaag cgccaatagg tgcccatcaa ccgtgacatc
     8041 ccaggcgaaa tggcaagcac taggaggaac ggggtcatga tgtacaccac cccttccaca
     8101 atggtccgta atagcggtac gaccttttga gcgacatagg acttcgagta gctttggaac
     8161 tttaagtcct tttggatcgc ctgctgctgc agaagcacag tgtccgcagt cgccgcgcgc
     8221 cgtttggcat cggcggattc ggcgtttttc cacgcatgga tgagcagcac attattaatc
     8281 atgtctcggg ccgattgccc gacggataac aagagattcg cccggatgtc ctcagtgagc
     8341 ccttcctcat cgccggtggc cggatc
//
LOCUS       DAOQPD010000110         8227 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_4804_length_8227_cov_21.072442, whole genome shotgun sequence.
ACCESSION   DAOQPD010000110 DAOQPD010000000
VERSION     DAOQPD010000110.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 8227)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8227)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8227
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4804_length_8227_cov_21.072442"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            146..565
                     /locus_tag="PK063_17280"
     CDS             146..565
                     /locus_tag="PK063_17280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98858.1"
                     /translation="MIRPVVQEERTGCGIAAAAALAGVSYARAKAVAKSLGIVASDRK
                     LWSETEYVRDLVAQFGLRAARTRQPFHSWASLPDYALLAIKWHLEQGRPFWHWVVFVR
                     ENDRSYVVDSSPTLKAPLRTDFGRMRPVWFLTVTMKR"
     gene            569..1807
                     /locus_tag="PK063_17285"
     CDS             569..1807
                     /locus_tag="PK063_17285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03862 family flavoprotein"
                     /protein_id="HMZ98859.1"
                     /translation="MNIAIIGGGPAGLMAAEVALAGGAQVALYDSMPSVGRKFLLAGK
                     GGLNLTHSDPSDLFLSRYGERRAQVAPWLAEFGPDALRTWARGLGIETYVGSSGRVFP
                     TDMKAAPLLRAWLRRLRQDGLTIHVRHRWCGWDEKKALRFETPHGATAVRADAVILAL
                     GGGSWPQLGSDGAWVPVLAGRSIAIAPLRPANCGFDVGWTEHFRTKFAGHPVKTVGVV
                     AKSPTGAVMRRMGEFVITDTGVEGGVIYAVAPFLRDEIEANGRGTLRLDLAPDRELPR
                     LIKDLSQPRGKKTMATHLQRRAHIDGVKAGLLREIVSKEDFADPTRLAAAIKALPLTL
                     TAPRPLHEAISTAGGVTCEALDKRLMLKALPGVFCAGEMVDWEAPTGGYLLTACFAGG
                     RTAGAGALAWLAERAERAKA"
     gene            1794..2351
                     /locus_tag="PK063_17290"
     CDS             1794..2351
                     /locus_tag="PK063_17290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HMZ98860.1"
                     /translation="MPRHNVTIDGMALVVPGIGNSGPRHWQTLWEQQHPRWQRVQQRD
                     WDRPVLTEWLPALESALAGISAPAVLIAHSMGCLLVAHWAQQASVPVRAALLVAPPDP
                     RSPAFPASARGFETVPSGRLPFPTLLVASSNDPFGSVAYAKQCATVWGSAFAEAGAIG
                     HINAESEIGAWPAGLVLLERLLASS"
     gene            complement(2415..>3110)
                     /locus_tag="PK063_17295"
     CDS             complement(2415..>3110)
                     /locus_tag="PK063_17295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HMZ98861.1"
                     /translation="AITKAACSGASWIITPELAVSGYTFADTLGTEWIEPQPDHWMSR
                     ICRLAARLGVTLFLSHPEKEPRSGQLYNTVFAIGPDGRIAGSHRKINALRVGSEAWST
                     PGTDATAFRLAPFGRVGLLICADAYTPGIAKSLKAQGATVLVSSAAWAPGLHGPNDEW
                     ERCTKDTGLPLFVCNRTGHDRTLDFRKAESVVAHNGKRLLSLSCEQSAIFLFDWNLTT
                     GTLADRGHQRILI"
     assembly_gap    3111..3210
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <3211..6478
                     /locus_tag="PK063_17300"
     CDS             <3211..6478
                     /locus_tag="PK063_17300"
                     /inference="COORDINATES: protein motif:HMM:NF024893.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="AsmA-like C-terminal domain-containing protein"
                     /protein_id="HMZ98862.1"
                     /translation="LLCVATILALPWLLNRPASMAALLQQVEARTGHRISFEQSHVEI
                     FPSPRVTLMQPRLYAATSPDPLLFAERVEVALQWLPLLEGSLVVKDLVIDRPRVTLRR
                     SPNGNWALGNEHSPGPDSEPTPPFALLQVVRNLLVVQGMVTLVDESASPSTSLNIIVT
                     QAALSSEMLGRRAKLHLSGELPQAGGRAAFLWEGSITQQGDEDGIQAEGDLRLHQLNV
                     RQVLSAWMGDGRITDGFSQPAQLTAHVRWKPGAAGYDLLADDVRAELADVSLQGSGAM
                     LGIGTAQARFSSSLSASPVTAARLLNEVPSAWMSSALRAQFVDHAVEGLITLQSLSIA
                     GDIAPGARPHINGLLAIRNGRFTLSSPYPPVEALTVSMVFDADQLRMTEVRAQCGPLR
                     LAGRDLLITQWATDPHIDVKITGTAPVSGLVETVRRLDEFPLLRDQVTDVEQPTGDVE
                     MIAHVMGRPLSGQPLTLVDADLRLQRGGGRSALLPMPVRQVDAHVTVTPTMVAIEHLN
                     GWFGPAAFQTHGSVTMADGKAYSNVTLAMSLEASELQSWWAEQAAEHFVPELDGSIRL
                     RAAVTGALGHPRVKGRIDLAEAGVRWQNWLTKPLQAPAAIDFEGQVSRDSHLLIRHVG
                     ITFPPVTVTASGTVDLDGEREFSAHVSSGRIAVARLPKGVVLGPVLAGTLEATLDMEG
                     RMTDRASWRTSGQIRFDEGTIKVENLDEPIRDAFVTLRFDRDRIHIPRMAFHVGASDL
                     RISGSIAQWADQPKARLVVESSQIDLAAFEMSRRRPSASARQRSSDHLWTDTTLHAFL
                     FADHVYYKKFLLTDLSTKITWDHGLLTVERISGDTNEGQLAGQVKIRTKNGQMEQARS
                     TFRASGIPVERVLSPFQERPALSGWLTTSGKVQAEFERGVLLPAALTSRQPIQILVEE
                     GRMHHIPVLSTLLSVLNLPAVLQGQVNLEKEGMPFDRLKLAGFINNGVVHTKEFLLDS
                     PVLKISGTGRYDLLADEFDMVLATSPLGSYSAILKRIPLFGHLLSGDRQGFDTAVFEL
                     KGSANKPQLRYLPAESLMTGVKGTAQLAFDILVNAITLPQKAFSMVEEGVTGGEEEDF
                     "
     gene            complement(6502..6873)
                     /locus_tag="PK063_17305"
     CDS             complement(6502..6873)
                     /locus_tag="PK063_17305"
                     /inference="COORDINATES: protein motif:HMM:NF016836.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BON domain-containing protein"
                     /protein_id="HMZ98863.1"
                     /translation="MPRSGTIFMETRYLRQPMRLVHRSFLFLPLLLCLSAGCLWTGTS
                     PLPDGPKDAVISTNVEAKFAEDQQGGLSGIIVTTEEGIVTLTGTVHKAERKARAAELA
                     RQVKGVRRVKNDLDIRADFAP"
     gene            6975..>8227
                     /locus_tag="PK063_17310"
     CDS             6975..>8227
                     /locus_tag="PK063_17310"
                     /inference="COORDINATES: protein motif:HMM:NF015451.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HMZ98864.1"
                     /translation="MAEPVADICVIGAGAAGLAAGIFAAERQPALRVEVLDGAASVGA
                     KILVSGGGRCNVTHDVVTPEDFFGTRHLVRNVLAAFPVKDTVAWFASLGVELKREETG
                     KLFPVTDKARTVLDALLRRSRELGVVLRPGHRVVNIERRTESEEGGTEARPGFVIRHQ
                     HGETPARRIILATGGRSLPRTGSDGGGYELVRHLGHHVTPTVPALVALMLDEDCFHAE
                     LSGLSQEVEIQTLVEGRSVDRRRGSLLWTHFGISGPVVMDASRFWCLARSRGEAAEVM
                     GNFLPGRNAEQAREWFLAQAAQNPRRSLLKVLAESLPERYAEVLCRHAGSDPQQACAQ
                     VPRAIRDRLLEALTRFRFPVVRDRGWNFAEVTAGGIPLEEVNFRTMESKLVPGLYLVG
                     EVLDCDGRIGGFNFQWAWATGRVAGR"
BASE COUNT         1461 a         2303 c         2699 g         1664 t
ORIGIN      
        1 acgaggccaa gcgtgtggcc cgctcgaacg gttgggccag gcttgaggtc accacgcctc
       61 cgttgccgca gttcgaccgg acgctggcgt tttatgagcg gcaggggttc agcgtgtccg
      121 gcggacggaa aatgaaagtg tcggtgtgat ccggccagtg gttcaggaag aacgaaccgg
      181 ttgtggcatc gcggcagcgg ccgcgctggc aggggtgtcc tatgcgcgtg cgaaggccgt
      241 ggcgaaatct ttaggcattg tcgcttcgga ccgaaaactg tggtcagaga cagaatatgt
      301 gcgagacctg gtggcgcagt tcggcctgcg agccgcacga acacggcagc cgtttcactc
      361 atgggcgagt ttgccggatt acgcgttgtt ggccatcaag tggcacctgg agcaagggcg
      421 accattctgg cattgggtcg tattcgtgcg agagaacgac cggtcgtacg tggtagattc
      481 cagcccgaca ttgaaggctc cccttcggac cgacttcgga cgtatgaggc cggtgtggtt
      541 tttgactgtg acgatgaaga ggtagcgagt gaatattgcc attattggag gcggaccggc
      601 cgggctgatg gccgcagaag tggcgctggc cggaggcgcg caggtcgcac tgtacgactc
      661 catgccttct gtgggccgaa aatttttact cgcggggaag ggcgggttga atctgacgca
      721 ttccgatcca tccgatcttt ttctcagcag atacggcgag cgccgggcac aggtcgctcc
      781 ctggttggcc gagtttggtc ctgatgcgct ccggacctgg gcacgggggc tcgggatcga
      841 gacctacgtc ggctcatccg gccgcgtctt ccccacggat atgaaggccg ccccgctgct
      901 gcgcgcctgg ttgcggcgct tgcgtcagga tggcctgacc atccacgtac ggcaccgctg
      961 gtgcgggtgg gatgaaaaga aagcccttcg attcgagacg ccccatggtg cgacggccgt
     1021 acgggcggat gccgtgatcc tggcgctagg tggaggcagt tggccgcaac tcgggtcgga
     1081 tggtgcctgg gtcccggtgc tcgccgggcg ctcgatcgcg attgctccct tgcggcctgc
     1141 gaactgcggg tttgatgtcg gctggacgga gcactttcga acgaagttcg cggggcatcc
     1201 ggtgaaaacg gtcggcgtgg tggcaaaatc tccaacgggc gcggtgatgc gtcgcatggg
     1261 agaattcgtg atcactgaca ccggtgtgga agggggcgtc atttatgccg tggccccgtt
     1321 tctccgggat gagatcgagg ccaatggacg aggcacgctg cggttggatc ttgcgccgga
     1381 ccgtgaactg ccacgcctca tcaaagatct gtcgcagcct cgtggaaaaa agacgatggc
     1441 gacgcacctg cagcgccgcg cgcatatcga tggagtgaag gccggattgc tgcgtgaaat
     1501 cgtttccaaa gaggattttg ccgacccgac ccgcctggcc gctgccatca aagccttgcc
     1561 gctcacgtta acggcgccgc gcccgttgca cgaagcgatc agtacggccg ggggagtgac
     1621 ctgtgaggcg ctggacaagc gattgatgct caaagcgctt ccgggcgtat tctgcgcggg
     1681 agaaatggtg gattgggaag cgccgacggg cggctatctg ctcacggctt gttttgccgg
     1741 tggacggacc gccggtgcgg gggccctggc ctggctcgcg gagcgcgcag agcgtgccaa
     1801 ggcataacgt gacgatcgac gggatggcct tggtcgtgcc gggtattggc aactcgggac
     1861 cgcgccattg gcagacgctg tgggaacagc aacatccacg ttggcaacga gtgcagcaac
     1921 gcgattggga tcgtcctgtg ctgacggaat ggctgccggc gctggagtcg gcgcttgccg
     1981 ggatatccgc cccggctgtg ctgatcgctc atagtatggg ctgcttgctg gtcgcgcact
     2041 gggcgcaaca ggcttcagtt ccagtgcgtg cggcactgtt ggtggcgccg cctgatccga
     2101 ggtctcccgc gttccctgcg tcagcgcgag gttttgagac agttccatct ggcaggctgc
     2161 cttttcccac tctcttggtt gccagcagta atgacccttt cggctctgtg gcctacgcca
     2221 agcaatgcgc gaccgtttgg gggagtgctt tcgccgaagc cggcgcaatc ggtcatatca
     2281 atgccgagag cgaaattggc gcatggcctg ccggtctcgt cttgctcgaa cggttgctcg
     2341 cgtcctcgtg atgtgccata cctgccacag gtctaaggct gcaacttcct aacaagtctt
     2401 cccgatccat ccatctagat cagtatgcgc tggtggcccc ggtcggccag cgtcccggtg
     2461 gtgagattcc agtcgaagag gaagatggcg gattgttcgc acgagagcga caggagccgt
     2521 ttcccattgt gagcgaccac actttccgct tttctaaaat cgagagtgcg gtcatgccct
     2581 gtgcgattgc agacgaacaa cggtagtccc gtgtctttcg tgcagcgctc ccactcgtcg
     2641 ttcggaccgt ggagtcccgg cgcccaggca gccgaagaca cgaggacagt ggccccctgc
     2701 gctttcaagc tcttggcaat gcccggggta taggcatcgg cgcagatgag gaggcccacg
     2761 cggccgaatg gcgccagacg aaatgcagtc gcgtctgtgc cgggggtgga ccaggcctcg
     2821 gacccgacgc gcaatgcgtt gatctttctg tggctgcccg caatgcgacc atcggggccg
     2881 atcgcaaata ccgtattgta gagctgcccg gatcgtggct ctttctccgg gtgcgacagg
     2941 aatagcgtga ctccgagccg tgcggcgagg cggcagattc tgctcatcca atggtcgggc
     3001 tgaggctcga tccactccgt cccgagcgta tcggcgaagg tgtacccgct gactgccagt
     3061 tccggggtga tgatccaact cgctcctgaa caggccgcct tggtgatggc nnnnnnnnnn
     3121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn gctcctctgt gtggcgacga tcctggcgtt
     3241 gccatggctg ctgaatcgtc cggcgagcat ggcggccttg cttcagcagg tcgaagcgcg
     3301 gacagggcat cggatttcct tcgagcaatc gcatgtcgag atctttccct cgccccgtgt
     3361 gacactgatg cagccccggc tctacgccgc cacctctccc gatccactgc tgttcgcgga
     3421 gcgggtggag gtcgcgctgc agtggctgcc gcttctggag ggatcccttg tcgtcaaaga
     3481 tctggtcatc gaccggcctc gtgtgaccct ccgccggtcg ccaaatggga attgggcgct
     3541 gggcaacgag cattcccccg gccctgattc agagcccacc ccgccgtttg cgttgttgca
     3601 ggtcgtgagg aatctgcttg tggttcaagg gatggtgacg ctcgtcgatg aatcggcttc
     3661 cccgtccact tctctcaaca tcatcgtgac gcaggctgcg ttatcgagtg aaatgttggg
     3721 ccgccgtgcg aagctgcatc tttcaggaga gctcccgcag gcaggcgggc gcgcggcgtt
     3781 cctctgggaa gggtccatca cgcaacaggg cgacgaagat ggaatacagg cagaagggga
     3841 tctgcgactc catcagttga atgtgcgtca agtgttgtct gcctggatgg gcgacggccg
     3901 aatcaccgat ggtttctcgc agcccgcaca attgacagcg cacgtgcggt ggaagccggg
     3961 cgcggcggga tatgatctgc ttgccgacga tgtgagagcc gagttggcgg atgtgtctct
     4021 gcagggaagc ggggcgatgc tcggaatcgg gacggcacaa gcacgatttt catccagcct
     4081 gtctgcatct ccggtaacgg ccgcccggct cttgaatgaa gtgccttccg cctggatgtc
     4141 ttctgcctta cgggcacagt ttgtcgacca tgccgtggaa ggattgatca ccctacaatc
     4201 tctgtcgatc gccggagaca tcgctcctgg agcacggcca cacatcaacg gcctgctggc
     4261 tattcgaaat ggtcgattca cgctcagttc accctaccct cccgtcgagg cgctgacggt
     4321 cagtatggtg ttcgatgccg atcaactgcg tatgacggag gtgcgcgccc agtgcggacc
     4381 ccttcgcctg gcaggccggg atttgctgat cacgcagtgg gcgaccgatc cgcatatcga
     4441 tgtgaagata acaggcacgg caccggtctc gggcctggtg gagacggtcc gccgtctgga
     4501 tgaatttccc ttgttgcgag atcaggtgac cgacgtggag caaccgaccg gggatgtcga
     4561 aatgattgcc catgtgatgg gacgaccgct cagcgggcag ccactcacgc tggtggatgc
     4621 cgatctccga ctgcagcggg gcggggggcg cagtgctctt ttgccgatgc cggtgcggca
     4681 ggtggacgcg cacgtcactg tcacgccgac catggtggcg atcgagcatc ttaacgggtg
     4741 gttcgggccg gcagcattcc agactcatgg ttccgtcacg atggctgacg ggaaagccta
     4801 ttccaatgtg acgctggcga tgagcctgga ggcgtcggag ctgcaatcct ggtgggcgga
     4861 acaggcagcg gaacacttcg tccccgagct ggacggcagc attcgcctgc gagcggccgt
     4921 gacgggtgca cttggacacc cgcgagtcaa aggccgcatt gatctcgcag aggccggggt
     4981 ccgttggcag aactggttga ccaagccgct gcaggcaccc gccgccattg atttcgaagg
     5041 gcaggtctct cgggacagtc atctgctgat ccggcatgtc ggtatcacgt ttccaccggt
     5101 caccgtgacg gcatcgggga cggttgactt ggacggggaa cgggagtttt cggcgcatgt
     5161 ctcgtcgggc cggatcgccg tcgcgagact tccgaaaggc gttgttctgg ggcccgttct
     5221 agccggcaca ttggaggcca ccctcgatat ggaaggccgg atgacagacc gtgcgtcctg
     5281 gcgcacctca ggccagatca gattcgatga aggcacgatc aaggtggaaa acctcgatga
     5341 accgattcgc gatgcgttcg tgacgctgcg cttcgatcga gaccggattc atattccccg
     5401 catggcgttt catgtcggcg cgagtgatct ccggatatcc ggctcgatcg cgcaatgggc
     5461 cgaccagccg aaggcccgcc tcgtggtgga gtcgtctcaa attgatctcg ctgcttttga
     5521 aatgtctcgg cgccgcccat cggcgtcggc gcgccagcga tcgtcagacc atctctggac
     5581 ggatacaacc ctccacgcgt ttctatttgc agaccatgtc tattacaaga agttcctgct
     5641 caccgacctc tcgacgaaaa ttacgtggga tcacggactg ctgacggtcg aacggatcag
     5701 cggggatacg aacgagggcc agctcgctgg gcaggtcaag atccgcacga agaacgggca
     5761 gatggaacag gctcgcagca ccttccgcgc cagcggcatt ccggttgagc gagtcctgtc
     5821 gccgttccaa gagaggcccg cgctctcagg atggctgacg acgtcgggaa aagttcaagc
     5881 ggaatttgag cggggagtgc ttctgcctgc cgcgttgacc agtcgtcagc cgatccaaat
     5941 cctcgttgag gaagggcgca tgcatcacat cccggtgctg tctactctgc tgtctgtgtt
     6001 aaacctcccg gctgtactgc aggggcaggt caacctcgag aaagagggca tgccgttcga
     6061 tcggctcaag ctggcagggt tcatcaacaa cggcgtggtc cacacgaagg aatttctact
     6121 cgacagtccc gtgctcaaga ttagtggaac cggtcgctat gacctcctgg cggatgaatt
     6181 cgacatggtg ctggcgacga gtccgctcgg atcctactcg gcgatcttga agcgcattcc
     6241 tctgttcgga cacctcctgt caggggatcg ccaggggttt gatactgctg tgttcgagtt
     6301 gaagggatcg gcaaacaagc cgcagttgcg gtatcttccc gctgaatcgc tgatgacggg
     6361 tgtgaaggga acggctcagt tggccttcga tattttggtg aatgcgatta ccttgccgca
     6421 aaaagccttc tcgatggtgg aagaaggggt gaccggaggg gaggaggagg atttctgacg
     6481 cccggctcag gcaacgatgt gttacggtgc aaagtcggcc cgaatgtcca gatcgttctt
     6541 gacgcgccgg acccctttca cctgccgcgc cagttcagcc gctctcgcct tccgttctgc
     6601 cttgtgcacc gtaccggtca gggtcacgat gccctcctcg gtcgtcacga tgatcccgga
     6661 gagtcccccc tgctgatcct cggcaaactt cgcttcgaca ttcgtggaaa tgaccgcatc
     6721 tttgggacca tccggcagcg gcgaggtgcc ggtccacagg catcctgccg aaaggcacag
     6781 cagcagcggg agaaacagga acgaccggtg gactaggcgc atgggctgtc gcaggtatcg
     6841 cgtctccata aaaatcgtcc cggatcttgg catagtgcgg ctccggtttc catgccgagt
     6901 tttgggattg cgcgtcctgt tcgcaacggg catcatgcgg cgccaggaat cagtatgttg
     6961 gagcacgagg gcagatggca gagccggtgg cggatatttg tgtaatcggg gcgggcgcgg
     7021 ctggattggc ggccgggatt tttgcggctg aacgtcaacc ggctctcaga gtggaagtgt
     7081 tggatggggc cgcgagcgtc ggcgcaaaaa ttcttgtttc aggcgggggg cgctgcaacg
     7141 tcacgcatga tgtcgtcaca ccggaagatt ttttcggtac ccggcacctc gtccggaatg
     7201 tgcttgcggc atttccagtg aaagataccg tcgcgtggtt tgcctcgctg ggtgtcgaac
     7261 tcaagcgtga agagaccggg aagttgtttc cggtgaccga taaggccaga acggtcctcg
     7321 acgcgctcct gcggcgaagt cgcgaactcg gtgtggtcct tcggccgggg catcgcgtcg
     7381 tcaacattga gcgcaggacc gaatcggaag agggcggcac agaagcgcgg cccgggtttg
     7441 tgatccgcca tcagcatgga gagacacctg cacgtcgcat catcctggcc accggcggtc
     7501 ggtcgttgcc gcgcactgga agcgacggag ggggatacga actggtacgg catctgggac
     7561 atcacgtcac accgaccgta ccggcattgg tggcgttgat gctggatgag gactgttttc
     7621 atgcggagct ttcaggcttg tcacaggagg tggagattca gacgctggtg gaagggcgat
     7681 cggtcgaccg gcgtagaggc agtctactct ggacgcattt cggcatcagc gggccagtcg
     7741 tgatggacgc cagtcgtttc tggtgtctgg cccgctcgcg aggtgaagcg gccgaggtca
     7801 tgggtaactt cctgccaggc cggaatgcgg agcaggcgag agaatggttc ctcgcgcagg
     7861 cggcccagaa tcctcgccgg tcattgctga aagtgcttgc ggagtcattg ccggagcgat
     7921 atgccgaggt gctttgccgt cacgccggga gcgatccgca acaggcctgc gctcaggtgc
     7981 cacgggctat tcgggaccgg ctgctggagg ccctcacccg ctttcgtttt cctgtcgtgc
     8041 gtgatcgcgg ctggaacttc gctgaagtga cagccggcgg gatccccttg gaagaggtca
     8101 atttccgcac catggaatcg aagctcgtgc ccgggttgta tctggtggga gaagtgctcg
     8161 actgtgatgg acggatcggc ggatttaatt ttcaatgggc ctgggcgacc ggccgggtgg
     8221 cgggccg
//
LOCUS       DAOQPD010000111         8120 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_4901_length_8120_cov_20.917421, whole genome shotgun sequence.
ACCESSION   DAOQPD010000111 DAOQPD010000000
VERSION     DAOQPD010000111.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 8120)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8120)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8120
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4901_length_8120_cov_20.917421"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(175..1644)
                     /locus_tag="PK063_17315"
     CDS             complement(175..1644)
                     /locus_tag="PK063_17315"
                     /inference="COORDINATES: protein motif:HMM:NF017809.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlkA N-terminal domain-containing protein"
                     /protein_id="HMZ98865.1"
                     /translation="MELLDPDISYRALQTRDARFDGRLFVGVISTGIYCRPICPARTP
                     KREHCRFFSGSAAAQAAGFRACLRCRPEIVPELPGWRGTSNTVSRALALIAEGFLDHE
                     DGTVEALAMRVGMGARQLRRLFDQHLGVAPVAVAQSRRLLFAKQLIHETKLSMSDVAL
                     AGGFGSVRRFNHAFRSLYHRAPGELRRDTTAASVTLAATAPVMLQIPYRPPYDWDSML
                     AYLRARAIEGLEVVEENAYRRSVLHEGLTGTITIEHRPDKHSLMATIDFPSVRALQAM
                     VARIRHQFDVAADIEAIAAHLSKDVTLAPLIAARPGLRAPGCWDGFELAVRAVLGQQV
                     TVAAARRLGGTLVGLWGEPLPHAVDRRLMRTFPTARCLATADLSRLGMPAARRATISA
                     LARTAISYPQLFMPGGSVEERLAQLRAIPGIGTWTAHYIALRAFREPDTFPATDLGLI
                     RSARRLIGEQTSASHLLERTEAWRPWRAYAAQYLWTADQ"
     gene            complement(1755..2705)
                     /locus_tag="PK063_17320"
     CDS             complement(1755..2705)
                     /locus_tag="PK063_17320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ98866.1"
                     /translation="MNCTKCPTSTRAVIGLPRHNAAFCKACFTTFVHEQVARAIKAFK
                     MFTPEDRILVAVSGGKDSLALWHILLALGYQADALYVNLGIGAYSEESHRKVRHYADT
                     VAASHGAKLLVHVVEQEAGAGIRELATILHRPTCSTCGTIKRYQFNRAAVEQEYDVMA
                     TGHNLDDEAARLLGNVLHWQNDYLDKQSPTLPASVEGFAKKVKPLCRLSEREIAAYAV
                     VNRIDYIVEECPMAKGSKMILYKEVLNRLETESPGTKQRFYWGFLDKQTAPAPATESM
                     AEKDQRTLAPCDTCGQPTTAGTCSYCKMMAKAKTAAQPRA"
     gene            complement(2805..3002)
                     /locus_tag="PK063_17325"
     CDS             complement(2805..3002)
                     /locus_tag="PK063_17325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoaD/ThiS family protein"
                     /protein_id="HMZ98867.1"
                     /translation="MLVQLSHPHRQVEIKGPKRTKELLRELNLVMEAHLVIRGDELVT
                     EDEMLADADQIEIRPVISGGT"
     gene            complement(3136..3291)
                     /locus_tag="PK063_17330"
     CDS             complement(3136..3291)
                     /locus_tag="PK063_17330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98868.1"
                     /translation="MVNEQNLDWKNSSFSAVDVNNQKYKRLALASAMLFLGVVALLIY
                     QIIQNIK"
     gene            complement(3558..4673)
                     /locus_tag="PK063_17335"
     CDS             complement(3558..4673)
                     /locus_tag="PK063_17335"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98869.1"
                     /translation="MRRASFPLISIGLGILLALLTMELVLRFLPVNEGARPQVVDHEH
                     PVRSLEPNRTFVWSADWNFAIVNVARTNNLGFVNDQDYLLDQPSPLLALIGDSYVEAL
                     MVPFRESVAGRLMTRSPSTERVYSFGTSSSALSNYLAYADYAAKQFHPQAMVFVIIGN
                     DFDESLLKYKNEPGHSYFVEDAHGTLALQRIDYHPSLWRRIIRASALVRYVTLNTDLL
                     NFVLKWQHLPFGRPSNHLAFVGNTGSKADPVRIADAQRAIDTFLTRVAEASGLPPHRI
                     LFAVDGMRPHIYNATTWQLTTGSYFDIMRQYFMEHARQQGFEVLDLQPRFAEHFAQHR
                     RPLEFATDNHWNSLGHEIVEEAIAHSDLYHWFRELAP"
     gene            complement(4769..5770)
                     /gene="galT"
                     /locus_tag="PK063_17340"
     CDS             complement(4769..5770)
                     /gene="galT"
                     /locus_tag="PK063_17340"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008108 - UDP-glucose:hexose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HMZ98870.1"
                     /translation="MPELRRDPIVGRWVIISTERSGRPQDVHMPSAPLPSAALCPFCP
                     GQERLTPREILAYRPHASEPDGPNWTVRVIPNKFPALQVEGDMGREGLGLYDRMNGIG
                     AHEVIIETPAHKESLGDLPAKRVEDVLWAYRDRILDLKKDLRLRYILIFKNHGAAAGA
                     TLEHSHSQLIALPVVPTSVLEEIDGCKQHFQQKERCIYCDIMRQESSEGTRVVLENPE
                     FLCLTPYAPRFPFEMWILPKRHAGYFEECQRTQFEFLAPMLGEALRRMDAVLARPAYN
                     FILHSSPLHEKTGDFYHWHIEIIPKLTQVAGFEWGTGFYINPVAPEEAAKCLRDAVL"
     gene            complement(5872..8076)
                     /locus_tag="PK063_17345"
     CDS             complement(5872..8076)
                     /locus_tag="PK063_17345"
                     /inference="COORDINATES: protein motif:HMM:NF015052.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 57 protein"
                     /protein_id="HMZ98871.1"
                     /translation="MKTIQLCFLWHMHQPYYTDPLTGSASMPWVRLHATKAYYDMAFL
                     LEHFPEARSTFNFTPSLLLQLEEFSAGRVRDLFLEHAQRPAADLTPTEKAFLIRHFFS
                     ANWATMVRPFPRYQELLVKRGIDVHGQDLERLARQFSTQELLDLQVWHNLAWFGYGSL
                     QRFPRLAELRAKNRAFTEEDKQEVLALQQTAIRQIVPMYKALQDRAQIELTTTPFFHP
                     ILPLVIDSEFTRRARPDLPLPARFHAPADAEAQVRRAVEYHTRTFGRAPAGLWPSEGS
                     VCPEVLPIVAQAGIRWLATDEGILYRSLQMAGQGWNRHYHLYQPYAVGTETHPLAMVF
                     RDRDISDAFGFVYHKTTPEAAADDVLRRIRSLAYDIRLDNGTIAVILDGENPWEHYHD
                     GGERFLSLLFRAFESDGLQLGNGIRVTLNTMSDAMKAAPPTQRLEQLHSGSWINQDFK
                     IWIGHQEDNRGWDLLQHTRARLVELTPSLEPDKARAAWDELYAAEGSDWFWWYGDDFD
                     TDYKQEFDRLFRTHLRNVWTYAGMTPPEILNQPLVEARTPQGLDLVQLPLALISPTLD
                     GLASNFFEWRGAGTINPTPPLGAMWKSEGLFTAIFFGFDREQLYLRLDFDERSDTRQE
                     QCSADLYIGSGIQQHRLSFALKAGAADHFQLARADESGTYRDRGSYSTICRQKILELG
                     IPFKDLDIEVGAELRLTLTVSEHGMEIARYPHHSPATFTRPDDDFEATMWRV"
BASE COUNT         1606 a         2250 c         2574 g         1690 t
ORIGIN      
        1 agtggcgcgt caacagtttc cgcatgcgat cctcgaaatc aacccaatcg accgcccgca
       61 actgcccctg ttcgtctgtc attatcacta aggttccaat cggcgtgatc aaggtttctg
      121 tcaaaaggtg tagttgttga gacatgatac atctccgtgc aggtggtgac agggctattg
      181 atcggcggtc cagaggtatt gtgcggcgta ggcgcgccat ggtcgccagg cctccgtgcg
      241 ctccaacaga tgagaggcac tggtctgttc tcctatcagg cgcctggcgc tccgtatcag
      301 accgaggtcg gtggccggga aggtgtccgg ttcacggaag gcacgcaggg cgatatagtg
      361 tgccgtccac gttccgattc cgggaatcgc ccggagttgc gcgagacgct cttcgactga
      421 tccaccaggc atgaatagtt gtggataaga gattgccgtt cgtgcaagag cgctgatcgt
      481 tgctcgccgc gcggcaggca tgccgagccg gctcaagtcg gcggtcgcga gacagcgggc
      541 cgtcggaaac gtgcgcataa ggcgcctgtc cactgcgtgt ggtaagggtt ctccccacag
      601 cccgaccaat gttccgccca gccgccgtgc ggccgcgacc gtaacctgtt gtcccagcac
      661 cgcgcggaca gccagttcaa aaccgtccca acagccaggg gcgcgcagtc ccggtcgcgc
      721 ggcgatgagg ggcgccaggg tcacatcctt tgagagatgg gctgcgatcg cctcgatgtc
      781 ggctgccacg tcgaattgat gccggatgcg cgcgaccatg gcctggaggg cgcggaccga
      841 tggaaaatct atcgtggcca tcaggctgtg cttgtccggt ctgtgctcga tggtgatagt
      901 gcccgtcagc ccttcatgga gcacgctacg gcggtaggca ttctcttcga caacctccag
      961 gccttcgatg gcgcgcgccc gtaagtatgc caacatgctg tcccagtcgt acggtggccg
     1021 ataaggaatc tgcagcatga caggtgcagt ggcggcgagg gttacgctcg ccgccgtggt
     1081 gtcacggcgc aattcgcccg gtgctcgatg atagagggag cggaacgcat gattgaaccg
     1141 gcggacactg ccgaatcctc ccgcaagggc cacatccgac atcgagagtt tcgtctcgtg
     1201 gatcaactgc ttcgcaaaca gcaggcgtct ggactgggcc acggctaccg gcgcgacgcc
     1261 caggtgttga tcgaagagcc ggcgtagctg ccgtgctccc ataccgacgc gcatcgcgag
     1321 cgcctcgacc gtgccgtcct catgatcgag aaatccctcg gcaatcagcg ccagcgctcg
     1381 ggagacggtg tttgacgtgc cgcgccaccc gggcagttcg ggaacaattt ccgggcgaca
     1441 acgcaggcag gcgcggaagc cggctgcttg tgccgccgca ctgccggaaa aaaaccgaca
     1501 gtgttcccgt tttggcgtgc gagccggaca gatcggccgg caatagatcc cggtcgagat
     1561 gacgccgacg aagaggcggc cgtcaaatcg ggcatcacgg gtctgcagcg cgcggtagct
     1621 gatatcggga tcgagcagtt ccatgcccac actctgccat attcaacgga gaaattccgg
     1681 ccgttttcgg acgtgaccat tcgattgcgg aggtcacaac aaaaatcgtg ggaggcgcgt
     1741 cgtcggttgg atggtcaggc gcgaggttgt gcggcggttt tggcctttgc catcatcttg
     1801 cagtaggagc aggtgccggc ggtagtgggc tggccgcagg tgtcgcaggg cgcgagcgtg
     1861 cgttgatctt tctcggccat ggattcggtc gcgggggctg gtgcggtttg tttgtccaga
     1921 aacccccagt agaaacgctg cttcgtaccg ggggattctg tttccagccg gttgagcact
     1981 tccttgtaga gaatcatttt cgagcccttg gccatggggc attcttcgac aatgtagtcg
     2041 atccggttga ccacggcata ggcggcgatt tcccgttcgg acaaccggca gaggggcttg
     2101 acctttttcg caaatccttc caccgatgcc ggtagggtgg ggctttgctt atcgagatag
     2161 tcgttctgcc agtgcaggac attccccagc agccgtgctg cttcgtcgtc gaggttatgg
     2221 ccggtggcca tcacgtcata ctcctgctcc actgccgcgc gattgaattg atagcgcttg
     2281 atcgttccgc aggttgagca ggtcggacgg tgaaggatgg tcgcgagttc acgaatgccg
     2341 gcccccgctt cctgctcgac gacatgcacc agcagttttg cgccatggga ggcggccacc
     2401 gtgtcggcat agtgccgcac tttccggtga gattcttccg aataggcccc gatgccgaga
     2461 ttcacgtaga gcgcgtcagc ctggtatccg agtgcgagga gaatatgcca gagggcgaga
     2521 ctgtccttgc cgccggaaac cgccacgaga atccggtctt caggtgtaaa cattttgaag
     2581 gccttaatgg cacgcgccac ctgttcgtgg acaaaggtcg taaagcaggc cttgcagaag
     2641 gcggcattgt gccgcggcaa tccgattacc gcgcgtgtac tggtcgggca cttcgtgcaa
     2701 ttcatggtgt tccaggtgtt ggcagtcagt cgtcaggttt cagcaagcgg gcgaagccgg
     2761 tcgacgatgg ctcgagaaat gccggtcgat cacggatcgt tgagctatgt cccgccggag
     2821 atcaccggcc ggatttcaat ctggtcggcg tcggcaagca tttcatcttc cgtcacgagt
     2881 tcatcgcccc ggatgaccaa atgcgcttcc atgaccagat tgagttcgcg cagcagttcc
     2941 ttggtgcgct tgggcccctt aatttcaact tgtctgtgag ggtgactcaa ctgaacgagc
     3001 atgcgcgatg atacggctga tacgcgcggg attgcaatcg gatcatgatc cgtcggagtc
     3061 aggcggagaa gtgtggtcgc gcgaggccgc cagaagcccg cttgcggctc attcctgacg
     3121 cgctagagga gagcattact taatgttctg aatgatctgg tagatcagca atgcgaccac
     3181 gccaaggaac aacatcgcgg aggccaaggc cagacgttta tatttctggt tgttgacgtc
     3241 cactgcactg aatgaggaat ttttccaatc aagattttgt tcgttcacca tgtcctccta
     3301 cctctaccgt cccggtattc tttgcctccc catcccgatc ctcgggatgc atatatgcat
     3361 tcactgagta ctgaagccga aggccgtccc gttccacccg aggccctagg gatagcacca
     3421 ggtttgtata cgctcgcatg cctgggaatt gcaaggaaag ctactagaca aaattctggt
     3481 aacgaccgag ttttatctaa tcgcccgagc gagcgtgctg gagacatcac tgactgtgcc
     3541 gtacaagaaa tcgtccgcta gggggcgagt tcccgaaacc agtgatacag atcggaatgc
     3601 gcgatggcct cttcgacgat ctcatgcccc agcgagttcc agtggttgtc ggttgcgaat
     3661 tcgagtggac ggcggtgttg ggcaaaatgc tcggcgaatc ggggttgcag gtcgaggact
     3721 tcaaacccct gttggcgggc gtgctccata aaatactgtc gcatgatatc gaaataggac
     3781 ccggtggtga gctgccacgt ggtggcgttg tagatatgcg ggcgcatacc gtcgacggcg
     3841 aagaggatcc ggtgtggcgg cagaccggat gcttcggcca cccgcgtcaa gaacgtgtcg
     3901 atcgctcgtt gggcatcggc aattcgcacg gggtcggctt tggacccggt gtttccgaca
     3961 aatgcgaggt ggttcgatgg gcggccaaat gggaggtgtt gccacttcag cacgaagttg
     4021 aggaggtccg tgttcagcgt gacatagcgc accagggcgg acgcgcgaat gatgcggcgc
     4081 cacagggagg ggtgatagtc gattcgttgc agcgccaggg ttccatgcgc atcttccaca
     4141 aaatacgagt gccccggttc attcttgtat ttcaacagac tctcatcgaa atcattgccg
     4201 atgatgacga agaccattgc ctggggatga aactgcttcg ccgcataatc cgcataggcc
     4261 aggtagttgc tcagagctga gctggatgtg ccgaaggaat agacgcgttc agttgagggg
     4321 gagcgggtca tcagtcgtcc ggcgacgctc tcccgaaacg gcaccatcaa cgcttcgaca
     4381 taactgtcgc cgatcagggc caggagcggc gacggctggt cgagtagata atcctggtcg
     4441 ttgacgaagc cgaggttgtt ggtgcgggcg acattgacga tggcgaaatt ccagtcggca
     4501 gaccagacaa acgtccggtt cggctccaga gaacggacgg gatgctcgtg atcgacgacc
     4561 tgggggcgcg ctccctcgtt gaccggcagg aaccgcagca ccagttccat ggtgagtagt
     4621 gccagcagaa tccccaagcc gatactgatg agcgggaaac tggcccgtct cataccggac
     4681 gggcaccaag ctggagagga agagatgaaa actcttcagc gggccctgcg gaacgggggg
     4741 ctagcggtat gcctgcgatg aagcccaatt atagaacggc atccctgagg catttcgccg
     4801 cctcttccgg tgccaccgga ttaatgtaga aaccggtgcc ccactcgaat cccgccacct
     4861 gcgtaagttt tgggatgatc tcgatgtgcc agtgatagaa atctcccgtc ttttcatgga
     4921 gtggcgagct gtgcaggatg aagttatacg ccggcctggc caggacggcg tccatgcgcc
     4981 ggagggcttc cccgagcata ggggccagaa attcgaattg ggtccgttgg cactcctcga
     5041 agtagccggc gtggcgcttc ggaagaatcc acatttcaaa gggaaatctc ggggcatagg
     5101 gcgtgaggca caggaattcc ggattctcca ggaccacgcg tgtgccttcc gaggattcct
     5161 gccgcatgat atcgcagtag atgcagcgtt ctttttgctg gaagtgctgt ttgcagccat
     5221 cgatctcttc gaggacgctg gtcggcacga ccggcaaggc gatcagttga gaatggctgt
     5281 gttccagcgt ggcaccggcg gcggccccat ggttcttgaa gatcaggatg tatcggagcc
     5341 ggagatcctt cttcaggtca agaatccggt cgcgataggc ccagagcaca tcctccaccc
     5401 gtttcgcggg gaggtcgccc aggctttctt tatgagcggg ggtttcgatg atgacttcgt
     5461 gggcgccgat tccgttcatg cggtcataca agccgaggcc ttcccggccc atgtctcctt
     5521 cgacctgcag tgccgggaat ttattgggta tgactcgcac ggtccagttc gggccgtccg
     5581 gttcagaggc atggggccgg tacgccagga tctctctggg cgtcagccgt tcctgtcccg
     5641 ggcaaaacgg acagagggcg gctgagggaa gcggcgccga cggcatatgg acatcctgag
     5701 ggcgtccgct ccgttcagtc gaaataatca cccagcggcc gacgatcggg tctcttctca
     5761 attcgggcat ctcaactcct gtggttcaaa tcaattgggc gtgatgctca ttgcgtaaaa
     5821 cgggcatcga tccgagtggt agcgtgatcc gcgagccgcg caccgttccg ttcagactcg
     5881 ccacatcgtg gcttcaaagt cgtcgtccgg ccgagtaaag gtggccgggc tgtgatgagg
     5941 ataccgcgcg atttccatgc cgtgttccga cacggtcagc gtcagccgca attctgcgcc
     6001 gacctcgatg tccaggtctt tgaacggaat gcctaattcg agaatctttt gccggcagat
     6061 tgtgctgtac gaacctctgt cgcgataggt gccggattcg tccgcccgtg cgagttgaaa
     6121 atgatccgcc gcgccggcct tcaaggcgaa ggacagtctg tgttgttgga tgcccgaacc
     6181 gatgtacaga tctgccgagc attgctcctg gcgggtgtct gatcgctcat cgaaatcgag
     6241 gcggaggtac agctgctcgc gatcgaatcc gaagaaaatg gcggtgaaca gcccctcgga
     6301 tttccacatc gctcccagcg gcggtgtggg attgatggtg cccgcgccgc gccattcgaa
     6361 aaagttcgat gccaagccgt ccagagtcgg gctgataagg gccagtggca attgcacgag
     6421 gtcgaggccc tgcggtgtgc gcgcttcgac caaaggctga ttcaagatct cgggcggcgt
     6481 catcccggcg taggtccaga cgttgcgcag gtgcgtgcga aacaggcggt cgaactcctg
     6541 tttgtagtcg gtatcgaaat catcgccata ccaccagaac caatcgctgc cctcggcggc
     6601 atacaattcg tcccaggcgg cgcgggcctt atcgggctcc agtgatggcg tcagttcgac
     6661 gaggcgtgcc cgtgtgtgct gcaggagatc ccaaccgcga ttgtcttcct ggtggccgat
     6721 ccagattttg aagtcctgat tgatccagga tccggagtgc agctgctcga gtcgctgggt
     6781 cggcggcgcg gccttcatgg cgtcactcat ggtgttcaag gtcacacgaa tgccattgcc
     6841 caattggagc ccatccgatt cgaaggcgcg aaagagcagg gagagaaacc gttcgccgcc
     6901 gtcgtggtaa tgctcccagg gattttcgcc gtcgaggatc accgcgatgg ttccgttgtc
     6961 cagccggata tcataggcca ggctgcggat ccgccggagc acgtcgtccg cggcggcctc
     7021 cggagtcgtt ttgtggtaga cgaacccgaa tgcgtcggag atgtcccgat cacggaacac
     7081 catggcgagg gggtgtgtct cggtcccgac cgcatagggt tggtagagat gatagtggcg
     7141 gttccaccct tggccagcca tctgcagcga gcgatagagg atgccctcat ccgtggccag
     7201 ccagcggatg ccggcttgtg ccacgatcgg taacacctcc gggcaaaccg atccttcgga
     7261 cggccagagc ccagccggag cgcggccgaa cgtgcgtgta tggtactcca cggcgcgcct
     7321 gacttgggcc tcagcatcgg ccggtgcatg aaaccgggct ggaagcggca ggtcgggtct
     7381 ggcgcgacgc gtgaactccg agtcgatgac cagtggaagg atcgggtgaa aaaacggggt
     7441 agtggtcagt tcgatctgtg cgcgatcctg aagcgcctta tacatgggca caatctgacg
     7501 gatggccgtt tgctgtaagg ccaacacttc ctgtttgtcc tcttcggtaa acgcacgatt
     7561 cttcgcgcgc aattctgcca ggcgggggaa tcgttgcaga ctgccgtatc cgaaccaggc
     7621 gaggttgtgc cagacctgaa gatcgaggag ctcctgagtg gaaaactggc gggccagccg
     7681 ttccaggtcc tgtccgtgga catcgatgcc ccgtttgacc agcagctcct ggtagcgagg
     7741 aaacggtcgg accatcgtgg cccagttcgc tgaaaaaaaa tggcggatga ggaaggcttt
     7801 ttccgtcggc gtgaggtccg ccgccggacg ttgtgcatgt tccaggaaca ggtcacggac
     7861 gcgtcccgca gaaaattctt cgagttgcaa cagcaaggac ggcgtgaagt tgaaggtcga
     7921 acgggcttct ggaaagtgtt cgagcaggaa ggccatgtcg taataggcct tcgtggcatg
     7981 caagcggacc cagggcatac tggcggaccc cgtgagcggg tccgtgtaat acggctggtg
     8041 catatgccag aggaaacaga gttgtatggt tttcatcggg aagtttcttg cagactcacg
     8101 ggcagtatgt cataggggta
//
LOCUS       DAOQPD010000112         7861 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_5122_length_7861_cov_24.524725, whole genome shotgun sequence.
ACCESSION   DAOQPD010000112 DAOQPD010000000
VERSION     DAOQPD010000112.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 7861)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7861)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7861
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5122_length_7861_cov_24.524725"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1908
                     /gene="dnaK"
                     /locus_tag="PK063_17350"
     CDS             <1..1908
                     /gene="dnaK"
                     /locus_tag="PK063_17350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HMZ98872.1"
                     /translation="GIDLGTTNSCVAIMSGGDPVVIANAEGSRTTPSVVGITDKNERL
                     VGQIAKRQAITNPENTIFSVKRLMGRKFKSKEVQEAMKRLPYKVVEADNGDAHVELRG
                     KRYSPPEVSAMILQKMRQTAEDYLGEKVTEAVVTVPAYFDDSQRQATKDAGQIAGLNV
                     LRIINEPTAASLAYGLDKKKDERIAVYDLGGGTFDVSVLEIGDGVFEVKSTNGDTYLG
                     GDDFDERVMDWLVEEFKKDQGIDLRKDRMALQRLKEAAERAKIELSSSQESEINLPFI
                     TADASGPKHMVTKLTRAKLEQLVDDLIQKTIEPCRKALADAGVSAKDIQEVVLVGGMT
                     RMPKVIQVVKDFFGKEPHRGVNPDEVVAIGAGVQGGVLKGEVKDVLLLDVTPLSLGIE
                     TLGGVFTKLIERNTTIPTKKSQVFSTAADNQTAVTIRVFQGEREMANDNKLLGQFDLV
                     GIPPAPRGMPQVEVSFDIDANGIVHVAAKDLATQKEQSIKITASSGLSKEEVDKLVKD
                     AQSHTEEDKKRRRVAEARNQADSLLYSTEKNLTEHGDKIGEDDKTKITEAIAGLRKAM
                     EGDDPAAIESATQALTTASHKLAEEMYKKASASAGPTDAGASAGDGGAQAKTDEKVVD
                     AEFEEVDKDKK"
     gene            1989..3101
                     /gene="dnaJ"
                     /locus_tag="PK063_17355"
     CDS             1989..3101
                     /gene="dnaJ"
                     /locus_tag="PK063_17355"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HMZ98873.1"
                     /translation="MAKRDYYETLGIERNATDDEVKKAFRKLARQHHPDLHTSPEQKK
                     SAEEKFKELNEAYEVISDPDKRRRYDTFGHAGGPQGAEGFDFGGQGGFGDIFNDIFED
                     FFGQPRGRARAERGNDLQYNLEITFEESVFGKEAKLKIPRWETCADCKGTGAKSATAI
                     KMCPACKGQGQLRFQQGFFSVSRPCGQCEGVGQIITEPCQVCGGRQRIRKERMLSVNI
                     PGGIETGMRLRLANEGEHGVQGGPQGDLYVAVTVKPHPHFRREGQDIACDLPINLVTA
                     ILGGRVEVPTLKGNTFMKIPAGTQPDKILRLKGLGFPNLKGGHTGDQLFNVKVEIPTK
                     LTSRQKELLEEFAKESGYTKDSEGEGFLDKMKTFFE"
     gene            3138..3875
                     /locus_tag="PK063_17360"
     CDS             3138..3875
                     /locus_tag="PK063_17360"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:TIGR00046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RsmE family RNA methyltransferase"
                     /protein_id="HMZ98874.1"
                     /translation="MPAFFISSAEIHGTALTLTGELCHHLRASLRVKPGEVLRLTDEH
                     RQRYEVRVSAVAPQALTAEILESRPGPIDTSPRVILAQVILKGDHMDWVVQKASELGV
                     KAVLPLISRHGVVRPQPERVAAQVARWQRIATEAAQQSEQWQPPQVLEPLEVRRFFSG
                     HQATTALLLAERQNAVGLANVPLPALPTDTITVIVGPEGGWAEEELSQAMDGQCLAVS
                     LGEHILRADTAAVTALSIVQSRLGRLG"
     gene            complement(3898..4869)
                     /locus_tag="PK063_17365"
     CDS             complement(3898..4869)
                     /locus_tag="PK063_17365"
                     /inference="COORDINATES: protein motif:HMM:NF026220.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YCF48-related protein"
                     /protein_id="HMZ98875.1"
                     /translation="MRTLAAVVCSLLVVFCVGTVEAGSPTVPVTVAMQKSGSEATLLG
                     MFFHDHQLGWAVGSGGTILKTTDGGHKWKKVSSGTSSLLTAVYFRDAKRGWVVGANGT
                     VRTSKDGGETWSVVVVSTQAPLYGIAFASPTKGWMVGGNGTILQTTDGGENWIDQASG
                     TSAALYAIALTNELQGTAVGALGTILTTADGGKNWTTQVSQSSATFFDVAFADDTNGW
                     AVGNAGALFQTIDGGTHWVDRTLPCGRTCNKLTDLIRVRFTDPQQGWIVGERGQILRT
                     SDAGFNWVEETSPVKRSLMALSFPRATAGWAAGEGGTIISISAAGNK"
     gene            complement(4881..6554)
                     /locus_tag="PK063_17370"
     CDS             complement(4881..6554)
                     /locus_tag="PK063_17370"
                     /inference="COORDINATES: protein motif:HMM:NF013955.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IPT/TIG domain-containing protein"
                     /protein_id="HMZ98876.1"
                     /translation="MKYITCAILGVALVANSVDSKAAPAEPPALHPNAAVPGATLSIT
                     GKGFGPFKSTRFNQVTFQGVPALIQRWDSDLIEVRVPSQAANGPVDIIIGKKHVKAGS
                     FTRLQPVIHSVSPAEAEPGSMLEIAGEHFGNTAGPRDPNTIFGVNSVAVGDVSVRVRK
                     WRDDKIEVELPGNVQSGDVVIRMSSSDPLPDGSCCAPVKQVVSNAMPMKVLASVRVDP
                     SSGPVGTKVVLFGKGFGTTRNPEDGVLFGGHLATVSQWTDTTVVVHVPLDAQTGPVVM
                     KRNGQERAIGTYTVQTPKATALTPTEAPIGTLLKITGENFGFYSEAGSTPFNYIDFSL
                     SENTVEIGGVQAIVYRWGHDRIDVWVPFSAKSGPVVVKRAANTPKPDGTCCADKQVLE
                     TQVGNFTLVTPKIDSYSPNTGGLDEVVTIKGSGFGKFLKTAEPSKVITDSVYARVAPE
                     LGENVSRTEVLFNGVGAIVQSWTDTEIKVKIPHRHSYGVGKLGEFNPDLTSGPLVVRR
                     GSWDLLPDGSCCTPKKWVTLEAGTFTIQPSGLPDASYWRNPNPENSHFH"
     gene            complement(6797..7258)
                     /locus_tag="PK063_17375"
     CDS             complement(6797..7258)
                     /locus_tag="PK063_17375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HMZ98877.1"
                     /translation="MSIDEKLSSLGLTLPVAPKPVASYVPAVLAGDLLYLSGILPFRD
                     GQVAITGKLGQDVTVERGAEAARLALLNALAVVKQELGSLDRVQRIVRVVGHVASATG
                     FVQQPAVINGASDLLVQIFGEAGRHARVALGAAELPLHAAIELELLVQVKA"
     gene            7483..7764
                     /locus_tag="PK063_17380"
     CDS             7483..7764
                     /locus_tag="PK063_17380"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98878.1"
                     /translation="MPSTMVQVPILMSPGQKRRLAQKAKAANLTMAELLREGGERYVP
                     ADNPTLLDHMAKQVIRETKKTIRAIDKTLALVAESEARMLALSKTRKKG"
BASE COUNT         1840 a         2379 c         2203 g         1439 t
ORIGIN      
        1 ggaatcgacc tcggcacgac gaactcctgc gtcgccatca tgagcggtgg agacccggtt
       61 gtcatcgcga atgcggaagg aagtcggacc actccgtcag tggtgggcat cacggataag
      121 aatgagcgct tggtgggaca aatcgccaaa cggcaagcca ttacgaatcc tgagaacacc
      181 atcttctccg tgaagcgcct gatgggacgc aaattcaaga gcaaggaagt ccaggaagcc
      241 atgaagcgcc tgccctacaa ggtcgtggag gcagacaatg gcgacgccca cgtcgagttg
      301 cggggcaaac ggtacagccc gccggaagtc tcggccatga tcctgcagaa gatgcggcag
      361 acggctgaag actatctggg cgaaaaggtc acggaagccg tggtgacggt tcccgcctat
      421 tttgatgaca gccaacgcca ggcgaccaag gacgccgggc aaatcgccgg attgaacgtc
      481 ctccgcatca tcaacgaacc gacggcggcc tcgctcgcct acggtctcga taagaaaaaa
      541 gatgaacgca tcgccgtgta cgacttgggt ggcggcacct tcgacgtgtc cgtgctcgag
      601 atcggcgatg gcgtgtttga agtgaagtcc acgaacggcg acacctacct cggtggcgac
      661 gatttcgatg aacgcgtgat ggactggctc gtcgaagaat ttaagaagga tcagggcatc
      721 gacctccgca aggaccgcat ggcgctccaa cgcttgaagg aagcggccga gcgggcgaag
      781 atcgaactgt cctcctctca ggaaagcgaa atcaatctgc cgttcatcac ggcagacgcc
      841 agcggcccga agcacatggt gaccaagctg acccgcgcga aattggagca gctggttgac
      901 gatctcattc agaagaccat cgaaccctgc cgcaaggcgt tggctgatgc gggagtgagc
      961 gcgaaggata tccaggaagt cgtcctggtc ggcggcatga cccgtatgcc gaaagtcatt
     1021 caggtcgtga aggacttttt cgggaaagaa ccccaccgcg gtgtgaaccc ggatgaagtc
     1081 gtggccatcg gcgccggtgt tcaaggcggc gtactgaagg gcgaagtcaa ggatgtgctg
     1141 ctgctcgacg tgactccgtt gtcccttggc atcgaaaccc tcggcggcgt ctttaccaaa
     1201 ctgatcgagc ggaatacgac gattccgaca aagaagagcc aggtgttctc aacggcggcc
     1261 gacaatcaaa ccgccgtaac gatccgggtc ttccagggcg aacgtgagat ggccaatgac
     1321 aacaagctgc tggggcagtt tgacctcgtc ggcattcccc cggccccacg cggcatgccg
     1381 caggtggaag tctccttcga tatcgatgcc aatggcatcg tccacgtcgc cgccaaagat
     1441 ctggcgacgc agaaagagca gtccatcaag atcacggcgt ccagcggact cagcaaagag
     1501 gaagtggaca agctggtcaa ggacgcgcag tcccatactg aagaagacaa gaaacgccgt
     1561 cgggtcgctg aagcccgcaa tcaggcagat tctctgctct acagcaccga gaagaacctg
     1621 accgaacatg gcgataagat tggcgaagac gacaagacca agatcaccga agccattgcc
     1681 ggcctccgta aggcgatgga aggagatgat cccgccgcca tcgaatcggc cacgcaagca
     1741 ttgaccacgg cctcccataa actggccgaa gaaatgtaca aaaaggcttc agcttccgct
     1801 ggtcctaccg atgccggcgc ttcagccgga gatggtgggg cgcaggccaa gaccgacgaa
     1861 aaggtcgtgg acgcggaatt cgaagaagtc gataaggata agaagtaagc tcctcactgc
     1921 aggcaggacc aggcttcacg gacggtgagg cttggtcctg ttgcacttag aacgggtaac
     1981 cctcttccgt ggcaaaacgc gattattacg aaaccctcgg tatcgaacgg aacgcgaccg
     2041 acgacgaagt caaaaaggcc ttcagaaaac tcgctcgcca acatcacccg gacctgcata
     2101 cctcgcccga gcagaagaaa tcggccgaag agaaattcaa agagctgaac gaagcctacg
     2161 aggtcatcag cgatccggac aaacgtcgcc ggtacgatac attcggccac gccggcggac
     2221 cgcagggcgc cgagggattc gatttcggcg gccagggtgg attcggcgat atcttcaacg
     2281 acattttcga agacttcttt ggtcagcctc gtggccgtgc ccgggccgag cgcgggaatg
     2341 accttcaata caatctcgag atcaccttcg aagagtcggt cttcggcaag gaagccaagc
     2401 tcaaaattcc tcgctgggaa acctgtgcgg actgtaaagg caccggcgca aaatccgcga
     2461 ccgccatcaa gatgtgtcct gcctgtaaag gacagggaca gttgcgtttc caacaaggat
     2521 tcttcagcgt cagccgcccg tgcggtcagt gcgaaggcgt cggacaaatc atcaccgaac
     2581 cgtgccaggt ctgcggtgga cgtcagcgca tccgcaagga acgcatgctg tcggtcaata
     2641 ttccaggcgg tatcgaaacc ggcatgcgcc tgcggctcgc caatgaaggg gagcatggtg
     2701 tgcaaggcgg cccgcagggc gacctctatg tcgccgtgac ggtcaaaccc catccccact
     2761 tccgccgaga agggcaggat attgcctgtg accttcccat caatctcgtg acggccatcc
     2821 tcggcggccg tgttgaagtg cccacgctca agggcaacac gttcatgaag attcctgcag
     2881 gcacgcagcc tgataaaata ctgcgactca aggggctcgg attcccgaac ctcaagggtg
     2941 gccataccgg ggatcaactg ttcaatgtga aagtggagat tcccacaaag ctcacctcgc
     3001 ggcagaagga actgctggaa gaattcgcca aggaaagcgg ctacacgaag gatagcgagg
     3061 gcgaaggctt tttagacaaa atgaagacgt ttttcgaata gaccgggctt ctgcaccttc
     3121 cagatccgcc gaccgtcatg ccggcatttt ttatctcctc agccgagatc cacggaaccg
     3181 cactcaccct taccggcgaa ctctgccacc atctgcgtgc cagcttgcgc gttaagcctg
     3241 gcgaggtcct gcgactcacc gatgaacacc gtcagcgata tgaggtgcgc gtgagcgcgg
     3301 tggctccgca ggcgttgacc gccgagattc tcgaatctcg tcccgggccg atcgatacgt
     3361 cgccacgagt catcctcgcg caagtcatac tcaagggcga tcatatggat tgggtcgtgc
     3421 agaaggcgag cgagttgggc gtgaaggctg ttctcccgct gatctcacgg catggcgtcg
     3481 tacgaccgca accagagaga gtggcggccc aggtggctcg ctggcagcgg attgccaccg
     3541 aagccgcaca gcagtcggaa caatggcagc cgccacaagt attggaaccg ttagaagttc
     3601 gccgcttttt ctccggccat caagccacca cagcacttct gttagcggag cggcagaacg
     3661 ccgtggggtt ggccaacgtt cccctaccgg ctcttccaac cgataccatc actgtgattg
     3721 ttggccctga aggcggatgg gcggaggagg aactgtctca ggctatggac ggacagtgcc
     3781 tggccgtaag tctgggggag cacatccttc gagcggatac ggcggcggtc acagccttaa
     3841 gtatcgtgca gagtcgattg ggacgattag gttagacggt agacaggcgg cgagtggtta
     3901 cttattgcct gctgcgctga tggaaatgat ggtccctccc tcgccggcgg cccagccggc
     3961 cgtggcacga ggaaaactga gcgccatcag agaacgtttc accggactgg tctcttccac
     4021 ccagttgaac ccggcatcgc tggttcgcag gatctggccg cgttccccaa cgatccaccc
     4081 ctgctgcgga tccgtgaacc gtacacgaat gagatccgtg agtttgttgc aggtccggcc
     4141 acagggcaag gtgcgatcga cccaatgggt tcccccatcg atcgtctgga ataacgcccc
     4201 ggcattgccg accgcccatc cgttggtatc atccgcaaag gcgacatcaa aaaaggtcgc
     4261 cgagctttgg ctgacctgtg tggtccagtt ctttccgcca tccgccgttg tgagaatcgt
     4321 gcccaacgcg ccgacggctg tgccttgcaa ttcgttggtc agcgcaatgg catacaacgc
     4381 cgcgctcgtg ccgctggcct ggtcgatcca gttctctccg ccgtccgtgg tctgcaaaat
     4441 agtgccgttc ccacccacca tccagccctt cgtcggagat gcaaaggcaa tcccgtacaa
     4501 aggcgcctga gtggacacaa cgacgacact ccacgtctcg ccaccatcct tgctggttct
     4561 gaccgtgcca ttcgccccca cgacccatcc gcgcttcgca tctcgaaagt aaacggcggt
     4621 caggagtgac gacgtgccgc tggagacctt cttccacttg tggccaccgt cggtagtctt
     4681 gagaatcgtc ccacctgatc caacggccca cccgagctgg tggtcgtgaa aaaacatgcc
     4741 taatagcgtc gcttcggagc cgcttttctg catcgcgacg gtcaccggaa cggtaggaga
     4801 accagcctcg accgtgccga cgcagaacac gaccaagagc gaacacacca ctgcagccaa
     4861 agtacgcaac gtaaagtgcc tcaatgaaag tgactgtttt caggattcgg atttcgccaa
     4921 taactggcat ccggcagacc ggacggttgg atcgtaaagg tgccggcttc caacgtgacc
     4981 cattttttgg gcgtacagca ggacccatcc ggcagcaaat cccacgaccc tctccgcacg
     5041 accagcggac cggacgtcag gtcaggattg aattccccaa gtttccctac tccgtaggag
     5101 tgacgatgag ggattttgac cttgatctcc gtatccgtcc aggactggac aatcgctccg
     5161 accccattga acaagacctc ggtacgcgag acattttcac ccaactccgg ggccacgcgg
     5221 gcatacacac tgtccgtgat gaccttgctc ggctcggctg tcttcaaaaa cttaccgaac
     5281 ccgctcccct tgatggtcac gacttcatcg agtcccccgg tgttcggact gtacgaatcg
     5341 attttcggcg tcacaagggt aaagttaccg acctgcgtct ccagcacctg tttatcagca
     5401 cagcaggtgc catccggctt cggcgtgttg gcggcgcgct tcaccaccac cggcccgctc
     5461 ttcgcgctga agggcaccca gacatcgatg cggtcatgtc cccatcgata cacaatcgcc
     5521 tgcacaccgc cgatctcgac ggtgttttcg ctcaatgaaa aatcgatata gttaaacggt
     5581 gtcgacccgg cctccgaata aaatccgaaa ttctctcctg taattttcaa caacgtaccg
     5641 ataggcgcct ccgtcggcgt cagcgccgtc gctttgggtg tctgcacggt atatgttccg
     5701 atggcgcgct cctgcccgtt acgcttcatc acaacaggac cggtttgagc gtcgagcggc
     5761 acatggacca cgacggtcgt atccgtccac tgcgacaccg tggccaaatg cccgccaaag
     5821 agtacgccat cctcaggatt tctggtggtt ccgaagccct tgccaaacag caccactttg
     5881 gtgccgaccg ggccgctcga aggatcgacc cgcacagacg ccaggacctt catcggcatc
     5941 gcattgctca ccacttgctt gaccggagca caacacgatc cgtccggcaa gggatcggat
     6001 gaggacatgc gaatcaccac atcgcccgac tgcacattcc ccggcaactc gacttcaatt
     6061 ttgtcgtcac gccacttgcg cacgcggacg ctcacatcgc cgacggccac gctattgacg
     6121 ccgaagatcg tattcggatc gcgcgggccc gcagtgttgc cgaaatgctc tccggcaatt
     6181 tctaacatcg agcccggttc tgcttcagcc ggtgatacgg agtgaatcac aggctgcaac
     6241 ctggtgaacg aaccggcttt cacatgcttc ttaccgatga tgatatcgac cgggccattg
     6301 gcggcctgcg acggcacccg cacctcgatg agatccgaat cccaccgctg aatcagcgca
     6361 ggcacgcctt gaaacgtcac ctgattgaac cgggtcgatt tgaagggccc gaaccctttg
     6421 cccgtgatcg acagtgtggc acccggcacg gccgcattgg gatgcagagc cggaggttca
     6481 gccggggctg ccttggagtc aacggaattc gccactaagg ctacgccgag gatggcacaa
     6541 gttatatatt tcatgggatc cactccctac cgataccctt tgaatgagcc tgacgagcag
     6601 gccgggtgag gatgaaatga atgatggtac gccagatgaa cgccccgcac gtggcacaaa
     6661 accccacgcc actgaggcaa cgaagccgga tggggggtgt ggtatcaaac cagaagactt
     6721 ccggactata acaagcggtt ttttttgatg tcaaggcaag caacgacgag ggaaaggaca
     6781 gcgcagaacg ggtacgtcag gcttttactt gaaccagtag ttcgagttcg atggcggcat
     6841 gcaatggcaa ctccgccgcg ccaagcgcca cacgtgcatg gcgtcccgcc tcaccgaaaa
     6901 tctgcaccaa taaatccgat gccccattga tcacggcagg ctgttgcaca aagccggtgg
     6961 ccgaggcgac atggcccacg actcgcacga tacgctgcac tcggtccaac gaccccagtt
     7021 cctgtttcac gaccgccaag gcgttcagga gcgccaatcg agccgcctcg gctccccgct
     7081 caaccgttac gtcctgtccc agcttgcctg taatggctac ctgcccgtcc cgaaacggca
     7141 agataccgct cagatacagc aaatcaccgg caagcaccgc cggcacataa ctggcaaccg
     7201 gcttcggcgc aaccggaagt gtgaggccaa ggctgctgag tttctcgtca atcgacacgg
     7261 tatgatcctt tcctgttcag caccccaccg aaggtcaggt atgcaagagc ccacgtagtg
     7321 caactcgaac attgagccct acgtatacgt catccgaggg cgattgagca agatgacccc
     7381 ctccagcatg catcataaac cgctgaggac atggggcgca tcgacagcat atccgatcct
     7441 atgatatata tgggctatat atccacgccg agggaggcct ccatgccatc cacgatggtc
     7501 caagttccta tcctcatgag ccccggccaa aaacgccggc tggcacaaaa ggcgaaagcc
     7561 gccaacctca ccatggcaga gctacttcga gaagggggcg agcggtacgt tccagccgac
     7621 aatccgacac tcttggatca catggccaag caagtcatcc gggagacaaa gaaaaccatt
     7681 cgcgccatcg acaaaactct cgccctcgtg gcagagtccg aagcgcgcat gctggctctc
     7741 tccaagaccc gtaagaaagg gtgacgatgg gactcaccga acgcgtgtgg gatgccttcg
     7801 ccaacaccat caagctgaac gataaagtgg agcaactcaa caccaccgtc gccaagcagc
     7861 a
//
LOCUS       DAOQPD010000113         7841 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_5134_length_7841_cov_21.699075, whole genome shotgun sequence.
ACCESSION   DAOQPD010000113 DAOQPD010000000
VERSION     DAOQPD010000113.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 7841)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7841)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7841
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5134_length_7841_cov_21.699075"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1309)
                     /gene="pheT"
                     /locus_tag="PK063_17385"
     CDS             complement(<1..1309)
                     /gene="pheT"
                     /locus_tag="PK063_17385"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: protein motif:HMM:TIGR00471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009328 - phenylalanine-tRNA ligase
                     complex [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HMZ98879.1"
                     /translation="MPTISLQRDDLEALIAGHGETASRISIDQLEQWLMLVKGELKGH
                     NIETGELRIELQDSNRPDLWCCEGIARQIRTKQQGTASSYPFFKKQKRAAGKLVVAPG
                     LEQVRPYVAACTAIGYRVTASGLAQLIQTQEKLADIFGRKRRTVSIGLYRLAPIVFPV
                     SYDLVKPDEVRFTPLGMETVMTLREILMVHPKGVEYGGIVSGHDRLPILRDAKGQVLS
                     FPPIINSREIGEVQVGDDHLFLEVTGTDLHMVALTLNIFAANLADRGAVIAPVEIQSP
                     VKTAFGKRWHTPIDFGAPRTIPLKAIETALGEALGSKEVTTALKSYGYTVKSGGPKVA
                     VQLPPYRNDLLHTVDVVEDVAISQGYARFAPVMPSQFTVGGLSRLEQMADRVRHLMVG
                     MEFQEIISNIMGSHQDFCSRMRLDGTEWANVVEVDNVMSLSYSC"
     assembly_gap    1318..1417
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(1477..3021)
                     /locus_tag="PK063_17390"
     CDS             complement(1477..3021)
                     /locus_tag="PK063_17390"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: protein motif:HMM:NF003210.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HMZ98880.1"
                     /translation="MDNLHPLESKVLLALAPQPGSPSTLDQLADSTGLEPSQLSMAVE
                     WLLAKSLIAVHAETVAYIASLTPIGEVFFEKYAPIERVLSAAREAGQTGKRLTIQDIQ
                     AKEALEPSDVSKAVGTLKKEGAILIVQGGCIESTGRNSSTAEAMRALLQELRSGQREL
                     QTFAEPLRAVLQQHAVKRGNAREPFRVDERVTRSFLLTPSGQEVADQLSRDGVAEEVS
                     QLTPELLKEGAWRTKQFRKYTISLRAPRIAAGKRHPYREFLDLVKLKLVSMGFQEMRG
                     TLVETEFWNMDALFMPQFHPARDIHDVYFVKNPTHARNIDEPYLTNVTQVHENGAGAG
                     STGWGYQFDAERAKRLVLRSQGTAVSARRLAANPSVPGKYFSIARCFRYDQVDATHAT
                     DFFQVEGIVLGTDINFRTLLGLLNLFAREVAQAKEVKFLPAYFPFTEPSVEMHVRHPK
                     LGWMELGGAGLFRPEVTTPLGVSVPVIAWGLGLDRMAMVALGIHDIRDLFSADLEFIR
                     TMRGSF"
     gene            complement(3049..3753)
                     /gene="rpe"
                     /locus_tag="PK063_17395"
     CDS             complement(3049..3753)
                     /gene="rpe"
                     /locus_tag="PK063_17395"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HMZ98881.1"
                     /translation="MAGRTVCIAPSILSADFARLAEEVAKVEEAGADWLHVDVMDGHF
                     VPNLTIGPPVVEALRKVTSLPLDVHLMMTNPDAFIGEFAEAGADYLTVHVETCPHLHR
                     TVQLIKERGVKAGVTLNPATPAITLSEIVGDADLILIMSVNPGFGGQKFIPSSLQKVA
                     AVRAMIDRTHSHALLEVDGGVKPDNADSILAAGADVLVAGSAVFSDHDYAAAITALRA
                     GRVSPPRSSRTMAGQR"
     gene            complement(3753..5192)
                     /gene="rsmB"
                     /locus_tag="PK063_17400"
     CDS             complement(3753..5192)
                     /gene="rsmB"
                     /locus_tag="PK063_17400"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: protein motif:HMM:NF011494.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HMZ98882.1"
                     /translation="MGTDPQPASPGHAVSPGRHAAVKALLAIEEAGTLSDDLFDQISA
                     KAGLDLRDRAFMVELVRGVLRYRATLDWRLGLLSDRRIAKLPTLVQIMLRLGAYQVLY
                     LDRVPASAAVNESVQMMKQLRRRLGRDWSGFVNAVLRAMLRASPPDWPDLARNPVEAL
                     AVQYSCPTWLVERWCRQWGAERAATLCRASVEVPPLTLRVNRLRTTRAALLADLGAAH
                     VEAEPTSISEVGIQLGRTSLVADLPGYPAGHFYVEDEAGQLVPLLLDVQPEHRVLDAC
                     AAPGGKATHIAALMANRGEIIAVDRVASRLDRVMDNCRRLGVTIVTPVVADMRELKAE
                     EAGAREPAISPALPEVQSRPFDRILLDAPCSGLGVLRRHPEAKWYKTPDSIAQHRQVQ
                     LDLLATTTRLLRPGGVLVYSTCSIEPEETESVIDEFCQSHREFQRDSIAPWLPPAGLP
                     FLTPRGDLSTMANRNNMDAFFAARLRRVG"
     gene            complement(5251..6201)
                     /gene="fmt"
                     /locus_tag="PK063_17405"
     CDS             complement(5251..6201)
                     /gene="fmt"
                     /locus_tag="PK063_17405"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HMZ98883.1"
                     /translation="MRIVFMGTPDFAVPSLEALLKSDDQVVGVVTQPDRPKGRGQEVI
                     PSPVKVVCQREGIPVLQPLKMKDPAFLDALREWQPDVIAVTAFGRILPPVILTLPPRG
                     CINVHGSLLPKYRGAGPLQWAIIRGERETGITTMFMAEGMDTGDMLLREAVEIRPDDT
                     AGTLAPRLADVGGRLLVETLRRLKAGTLTPERQDDSQATMAPLLKKEDGLIDWTLSAQ
                     EIANRVRGLSPWPGAYSYVNGERWTLCRVAVGDASQQAAPGTVTKVTKDRIDVATGAG
                     AIQILDIQPSNSRRMTVAQYLAGHRVAEGISLHAVPPPQA"
     gene            6289..6365
                     /locus_tag="PK063_17410"
     tRNA            6289..6365
                     /locus_tag="PK063_17410"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6323..6325,aa:Met,seq:cat)
     gene            complement(6384..7484)
                     /locus_tag="PK063_17415"
     CDS             complement(6384..7484)
                     /locus_tag="PK063_17415"
                     /inference="COORDINATES: protein motif:HMM:NF012798.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HMZ98884.1"
                     /translation="MMALFRRNRVWWMGFSYCGKQVRRSTEVTDKKVAEKIYHKVRTQ
                     IAEGKWYEPARGDDKTVKELLERYLRDHSAVNKSSSSQRSDRSVSVHLIRAFGDLTLK
                     ELRPSLIAAHKAKRRAEGAAAKTINIELGILSHAFQLAVKEWEWVTENPVIRVSREKV
                     RNVIERWLTAEEEQRLLAASPQWLQEIIVFAANTGLRQGEILDLQWSRVDLFRRTITL
                     LEQKNGAKDTLPVNAKTFEVLKARARVRSLKSDYVFFNGAGNRMDARDLLRVFYPVMR
                     KADVKNFRFHDLRHTFATRLVQAGVDIYTVQKLGRWKTISMVMRYAHHHPESLRAGVE
                     ILDRVPAGVSTNLAQSASQTGADRGVETAVSG"
     gene            complement(7481..7777)
                     /locus_tag="PK063_17420"
     CDS             complement(7481..7777)
                     /locus_tag="PK063_17420"
                     /inference="COORDINATES: protein motif:HMM:NF024139.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HMZ98885.1"
                     /translation="MLTVKELSAWLNIKPSTLYLWVSQNKIPCRRIHGLVRFEPEAIQ
                     AWLNGFSSTPSNQPLRVPRQRAEDVDHLIAVAKAVHYTSRREKPDKDRATQGGQ"
BASE COUNT         1659 a         2396 c         2095 g         1591 t
ORIGIN      
        1 ggcacgaata gctaagcgac atcacattat ccacttccac gacgttcgcc cactcggtgc
       61 catccaagcg catgcgcgag caaaaatcct gatgagaccc catgatgttg gaaatgattt
      121 cctgaaattc catccccacc atgagatgac gaacccggtc ggccatttgc tccaaccgtg
      181 acagccctcc caccgtaaac tgcgagggca tgaccggagc aaaccgtgca tatccctggc
      241 tgatcgccac atcctctacc acatcgacag tatgcagcag gtcgttgcga tagggcggca
      301 attgcacggc gactttaggc ccgcctgatt tcaccgtgta gccgtaggac ttgagcgccg
      361 tggtgacttc tttgctaccc aacgcttctc ccagcgcggt ttcgatagcc ttgagcggaa
      421 tcgtccgcgg cgcgccgaaa tcgatcggtg tgtgccagcg cttaccgaag gcggttttca
      481 ccggcgactg aatttcaacc ggcgcaatga cggctccacg gtcggccagg ttcgcggcaa
      541 aaatgttcaa tgtcagcgcg accatgtgaa gatcagtccc ggtcacctct aggaacagat
      601 gatcgtctcc gacctgcacc tcgccgattt cacggctatt gatgatcggc gggaacgaca
      661 ggacttgccc tttggcatca cgcaatatcg ggagtcgatc gtgaccgctg acgatgccgc
      721 catactccac acctttcgga tggaccatca ggatctcgcg cagagtcatc accgtttcca
      781 tgcccaacgg ggtgaaccgc acttcatccg gcttcaccag atcgtacgat acgggaaaga
      841 caatcggcgc gaggcgatag aggccgatgg acaccgtgcg gcgcttgcgc ccgaaaatat
      901 ccgccagctt ttcctgcgtc tggatcagtt gcgccagacc ggaggccgtc acacgatagc
      961 cgatcgccgt acaggccgcc acatacggcc gcacctgctc cagcccgggt gccacgacga
     1021 gttttccagc ggcacgtttt tgcttcttga aaaaggggta ggaactggcc gtgccctgct
     1081 gcttggttct gatctgccgg gcaatccctt cgcaacacca caaatccggc cggttgctgt
     1141 cctgcagctc gattcgtaat tcaccggttt cgatattgtg ccccttcaac tcgcctttca
     1201 ccaacatcag ccattgctca agctggtcga tcgaaatacg ggacgccgtt tcgccatgac
     1261 cggcgatcaa cgcctcaaga tcgtctcgtt gtagagaaat ggtgggcatg atgtgatnnn
     1321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnngcg atcaacgcct caagatcgtc
     1441 tcgttgtaga gaaatggtgg gcatgatgtg atcgtcctaa aaacttccgc gcatggtccg
     1501 aatgaattcc aaatccgccg aaaagaggtc gcgaatatcg tgaataccca acgccaccat
     1561 cgccatacga tccagcccga gtccccaggc aatgaccggc acagagactc cgagcggcgt
     1621 cgtgacttca ggccggaaca atcccgcgcc tcccagctcc atccagccca acttcggatg
     1681 gcgcacatgc atttcaaccg acggttcggt gaacgggaaa taggcgggaa gaaacttcac
     1741 ttccttggcc tgcgccactt cacgggcgaa caggtttaac aatcccaaca acgttcgaaa
     1801 gttgatatcc gttcccaaca caatcccttc tacctggaaa aaatcagtag catgggtggc
     1861 gtccacctgg tcgtaacgaa aacagcgggc gatcgaaaag tactttccgg ggacggatgg
     1921 gttggcagcg agcctgcgcg cagaaaccgc cgtcccttgg cttcgcaaca ccaaccgctt
     1981 cgctcgctcc gcatcgaact gatagcccca accggtcgat ccggcccctg cgccattctc
     2041 atggacctgt gtcacattcg tcagatacgg ttcatcgatg ttgcgggcat gggtcgggtt
     2101 tttcacaaag tacacgtcgt ggatatcgcg cgcgggatga aactgcggca tgaacagagc
     2161 gtccatattc caaaactccg tctccacgag cgttccacgc atctcctgga agcccatgct
     2221 gaccagcttg agtttcacga gatccaggaa ttcccgatac gggtgccgtt tcccggccgc
     2281 gatcctcgga gcccgcaagc tgatcgtata cttccggaac tgcttcgtcc gccaggcacc
     2341 ttccttgaga agctcgggcg tcaattggga aacttcttct gcgacgccgt cacgcgacaa
     2401 ctggtcagcc acttcctgac cggaaggcgt cagcagaaac gatcgcgtca cccgttcgtc
     2461 gacccggaag ggctctcgcg cgttcccgcg tttgaccgca tgctgctgaa gcacagcccg
     2521 gagcggttcc gcaaaggtct gcaactcacg ttgtccgctt cgcaattcct gcaagagggc
     2581 acgcatggcc tctgccgtgg aactattccg gccggtgctt tcgatgcagc caccctgtac
     2641 gatgagaatg gcgccttctt ttttgagggt gccgaccgct ttactgacat ccgacggttc
     2701 aagcgcttcc ttggcctgaa tgtcctggat ggtcagacgt ttgccggtct gcccggcttc
     2761 ccgtgccgcc gacagcacgc gttcaatcgg cgcgtatttc tcgaaaaaca cctcaccgat
     2821 cggcgtcaac gacgcaatat acgcaaccgt ttcggcgtga acggcaatga gggatttggc
     2881 caagagccat tcgacggcca tacttaactg cgaaggttcc agcccggtgg agtccgcgag
     2941 ttgatcgagc gtggagggcg agccaggctg cggagccaat gccagcagca ctttgctttc
     3001 gaggggatga agattatcca tgaatgacgg tgcggtccga tgcctctgct atcgctggcc
     3061 ggccatagtt ctgctgctgc gtggcggtga tacccgaccg gccctgaggg ctgtaatcgc
     3121 ggcggcataa tcgtgatcgg aaaatacggc ggatcctgct accaacacat cggcccccgc
     3181 cgcaagaatg gaatccgcgt tatccggttt caccccaccg tccacctcaa gaagcgcatg
     3241 gctgtgggtc cggtcgatca tggcccggac tgcggcgacc ttttgcaagg acgagggaat
     3301 aaatttttgc ccgccgaatc cgggattcac ggacataatg agaatgagat cggcgtcgcc
     3361 cacaatttcg gaaagggtga tcgccggtgt ggcgggattc aacgtgaccc cggcctttac
     3421 gcctcgttct ttgatcaatt gcacagtccg atgcaggtga ggacaggttt ccacgtgcac
     3481 ggtcagatag tccgcgccgg cttcggcaaa ctccccgatg aacgcatccg gattggtcat
     3541 catcagatgc acgtccagcg gcaggctggt cacttttctc aacgcttcaa cgaccggggg
     3601 gccgatcgtc aggttcggca cgaagtgacc atccatcaca tccacatgca accaatcggc
     3661 gcccgcttct tcgactttgg cgacctcttc cgccagacgt gcgaaatctg ccgatagaat
     3721 agatggcgca atacagacgg tcctgccagc cattacccaa ccctccgcag acgggcggca
     3781 aaaaacgcat ccatgttatt tctattggcc atcgtagaca gatcccctcg aggggtcaga
     3841 aacggcagac cggctggggg caaccagggc gcgatcgaat cgcgctgaaa ttcacgatga
     3901 gactgacaaa actcgtcgat gaccgactcg gtttcttccg gctcaatcga gcacgtacta
     3961 tagaccaaca ctccaccagg ccgcaagaga cgagtcgtcg tggcgagcag gtccagctgc
     4021 acctgtcgat gttgcgcgat ggaatccggc gtcttgtacc atttggcttc tgggtgacgc
     4081 cgcagcacgc cgaggccgct gcacggggca tcgagtaaaa tccgatcgaa cgggcgcgat
     4141 tgcacctccg gcagcgcggg agagatcgct ggctctctcg cccccgcctc ttcggctttc
     4201 agctctcgca tgtcagctac gactggcgtg acgatcgtca cacccaggcg ccgacaattg
     4261 tccatcaccc ggtccagacg tgatgcgact ctatcaaccg cgatgatttc acctcgattg
     4321 gccatgagcg cggcgatatg cgtcgctttg ccgccaggtg cggcgcaggc atccaacaca
     4381 cggtgctccg gctggacgtc caagagcaga ggcaccagtt gcccggcttc atcttcgaca
     4441 taaaaatgtc ccgccgggta tccagggaga tcggcgacga gactggtgcg gcctagttga
     4501 atgccgactt cgctgatcga cgtgggctcc gcttcgacgt gcgccgcgcc caagtcagcc
     4561 agtagcgccg ctcgcgtggt tcgaagccgg ttcacacgaa gtgtgagcgg aggcacttca
     4621 accgaggccc ggcataaggt tgcggctcgt tcagcccccc actgtcgaca ccagcgttcc
     4681 acgagccatg tgggacatga gtactgaacg gccagtgcct cgacaggatt cctcgcgaga
     4741 tccggccaat ccggaggcga cgcccgcagc atggcccgca gtacggcatt gacgaatcca
     4801 ctccaatcgc gccccaagcg ccgtcgcagc tgcttcatca tctgcacgga ttcgttcact
     4861 gctgctgagg ccggcacccg atccaggtac agcacttgat acgcgcccaa gcgcaacatg
     4921 atttgcacga gagtgggaag tttggcgata cgccgatcgg acaagaggcc tagacgccaa
     4981 tccagcgtcg cgcgataccg caacacaccg cgcacgagtt ccaccatgaa ggctcgatcg
     5041 cggagatcga gcccggcctt cgcagaaatc tgatcgaaca agtcatcgga caacgtgccg
     5101 gcttcctcga tggccaataa cgccttgacg gcggcatgcc gcccgggaga aacggcgtga
     5161 ccgggtgacg ctggttgcgg atcagttccc atgggcacta gacatgaaca tcgccggaaa
     5221 tggtgaatgg aatgcgcgtg ccgcgctggg tcaggcctgt ggaggcggaa cagcgtgcag
     5281 actgatacct tcagccacac gatggcctgc cagatattgc gccaccgtca tacggcggct
     5341 attggatggt tggatgtcga gaatctgaat ggctcccgca ccggtcgcga catcgatgcg
     5401 gtctttcgtc accttcgtga cagtgcccgg agccgcttgc tgagatgcat cgccgaccgc
     5461 aacgcggcag agagtccacc gttcaccgtt cacatagcta tatgcgccgg gccagggaga
     5521 aagtccccgc acgcggttgg cgatctcctg ggccgatagc gtccaatcga tgaggccgtc
     5581 ctccttcttg agcaacggcg ccatagtcgc ctgagaatca tcctgacgtt ccggcgtcaa
     5641 cgtccccgcc ttcaggcgac gcagggtctc gaccagcaac cgtccgccca catccgcaag
     5701 ccgaggggcg agtgtgccgg ctgtatcgtc tggacggatt tctacagcct cacgcagcag
     5761 catatcgccg gtgtccatcc cttcagccat gaacatagtc gtaatgccgg tttcccgctc
     5821 accgcggata atggcccatt gcagaggacc agccccgcga tacttcggca aaagcgaccc
     5881 atggacgttg atgcagcctc gaggcggcag cgtcagaatg accgggggga ggatacggcc
     5941 gaaggcagtc accgcaatga catccggctg ccactcgcgt aatgcgtcca gaaaagccgg
     6001 atccttcatc ttcagtggtt ggagcacggg aatgccttcg cgctggcaga cgactttcac
     6061 cggggaagga atgacctcct gcccgcggcc tttcgggcga tccggctgtg tcaccacgcc
     6121 gacgacctga tcatcggact tcagtaacgc ctccaatgag ggcacggcga agtcgggtgt
     6181 tcccatgaat acgatacgca tgctctggct ttatcattct cccttcgcga atgcaattct
     6241 cgtcgcggct tccttgactc tcgtttcaca cgcctgttag tatccggtcg cggggtggag
     6301 cagcctggta gctcgttggg ctcataaccc aaaggtcgtc ggttcaaatc cggcccccgc
     6361 aaccaacctt tcccacactt ctttcaacca cttacagcag tttcaacacc gcgatccgca
     6421 cccgtctgag aagccgattg tgctaaattt gtgctaactc ctgccggaac gcgatccaag
     6481 atctctacac cagcacgcaa actctcagga tgatgatggg cataccgcat caccatggaa
     6541 atggttttcc atcgtccgag tttctgcacg gtgtaaatat cgactccggc ctgcacaaga
     6601 cgggtggcaa aggtatggcg cagatcgtgg aaacgaaagt ttttcacgtc tgccttgcgc
     6661 atgacaggat agaacacgcg aagcagatct cgcgcatcca tccgattgcc cgcaccgttg
     6721 aagaacacgt aatcgctttt gagcgaacga accctggctc tagctttcag tacctcaaac
     6781 gtctttgcat taacaggaag ggtatccttc gctccgttct tctgctccag caaagtaatg
     6841 gtccgccgga agagatcaac cctggaccat tgcaggtcga ggatttcccc ctgccgaagc
     6901 cccgtatttg cggcaaagac aatgatctcc tgaagccatt gcggtgaggc cgccaacaat
     6961 cgctgctcct cctccgctgt aagccaccgc tcaatcacgt tacgcacttt ctccctcgat
     7021 acgcggatca ccggattttc cgtcacccac tcccattctt tgacggcaag ctgaaaggcg
     7081 tggctcaaga tccctaactc gatattaatg gtcttggccg ccgctccttc tgctcgccgc
     7141 ttcgccttat gtgctgcaat aagagaaggg cgcagttcct tgagggtcag atccccgaat
     7201 gctcgaatga gatgcaccga cacagaccta tcacttcgct gagaggaaga agacttattg
     7261 accgctgaat gatctcggag atagcgctcc aacaattcct tcaccgtctt atcatctccc
     7321 cttgctggct cgtaccactt cccttcagcg atctgagtcc tcaccttgtg ataaatcttt
     7381 tcagccactt tcttatccgt cacttcagtg gatcttcgga cctgtttgcc acagtaagaa
     7441 aaccccatcc accagactcg gtttctccga aacagtgcca tcattgccct ccttgtgtgg
     7501 ccctgtcttt gtctggtttc tcgcgcctgg aagtatagtg aacggccttc gcgacagcaa
     7561 tcaggtggtc tacgtcctca gctctctgcc gaggcacacg aagtggctgg ttcgaaggcg
     7621 tggaagaaaa gccgttcagc caggcctgaa tcgcctcagg ttcaaagcgg acgaggccat
     7681 gaatgcgacg gcacggaatc ttattctgtg aaacccagag gtagagtgtg gacggcttga
     7741 tattgagcca agccgagagc tctttgacgg taagcatggt acagatcacc gggggagtct
     7801 cccgacaccc ccagtccccc taacatgggc tgcccgcgtg a
//
LOCUS       DAOQPD010000114         7820 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_5153_length_7820_cov_19.352093, whole genome shotgun sequence.
ACCESSION   DAOQPD010000114 DAOQPD010000000
VERSION     DAOQPD010000114.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 7820)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7820)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7820
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5153_length_7820_cov_19.352093"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            923..2098
                     /locus_tag="PK063_17425"
     CDS             923..2098
                     /locus_tag="PK063_17425"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013884.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HMZ98886.1"
                     /translation="MTRSATPVMSLSPNLDFLRAIAVLLVYFFHLFITTGPRLPDFLA
                     QFGVILFFVHTSLVLMFSLQRIDLKGQRLFATFYLRRLFRIYPLSIVCVSVIILLQLP
                     RAPWWPWTQPDTSTILANLLLYTEFTYKPVVTSVLWSLPYEVAMYAVLPFCYLAGKAY
                     GIRGILALWGLAVVGGFVQPYISWRLGLAQFAPCFIAGVACYFMGYGARRRPLPFWGW
                     PLILLAAAGIQGFGSYYEYEQVSRWVLCLMIGLTAPFFAELNRPMLNKATELIARYSY
                     GIYLTHLHAQWAALVLLKDQPAAVRYSVLVVLSVGLPVALYHMVEAPMIRLGARLAAN
                     LPTKSVPVVRPASPQRALPAPAEAAPYGRPSQPVRPRPGQAPAVRTGKSAPAPASAR"
     gene            2306..2932
                     /locus_tag="PK063_17430"
     CDS             2306..2932
                     /locus_tag="PK063_17430"
                     /inference="COORDINATES: protein motif:HMM:NF025729.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4412 domain-containing protein"
                     /protein_id="HMZ98887.1"
                     /translation="MLTRFLLCLVLAAATLPTAGLALAAERTNVEYSADQIIESEDGA
                     TKSRIYSTPTKERRDMSQGGAAMTMITRHDKHVSWTVMPEEKMYMEAPATKQGQDKSD
                     LSGYQIEQTALGEETVNGVVMNKSKIIMTGNDGTKMGGFMWTTKEGILAKIDALAVEK
                     GQKARFKMEQTNIQIGKQPAELFEIPKGFEKLDMGGMGMDMLKGMMGR"
     gene            3063..3851
                     /locus_tag="PK063_17435"
     CDS             3063..3851
                     /locus_tag="PK063_17435"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98888.1"
                     /translation="MKKAEELERAGQPREAFSAATKANGDCVSDTQRHEGVQQRTAKA
                     IGAEEEKKARLEDAFTWYVRAKAPADAGRMQRRLVEAKPDDINTLSHAIDYFSQQNDK
                     AQEEAMRTRARKNVEQALAEEEKRFASFSRDSLHELGRARDWAYYAKTGEDRIRARAA
                     QRGDTLAAEDGRKFLRLAMSYYEQADRPDGVKKIREKARMLAKRHEAKGEGEIAAEFY
                     AMAGDDKQADTVQKHTEQRQTQAEEGRKKTFKKEQADLEKALGF"
     gene            4128..7586
                     /locus_tag="PK063_17440"
     CDS             4128..7586
                     /locus_tag="PK063_17440"
                     /inference="COORDINATES: protein motif:HMM:NF024180.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAT domain-containing protein"
                     /protein_id="HMZ98889.1"
                     /translation="MAKKQSGTVSWATSAEWDVRTLEPARGGRRGATEPPDPFLVNLT
                     ATKRWEVEQTLTATPKARRGETAPAPPLTLDVEADPDDVYIVMTRYASGAIRFHMPNE
                     PARRGRRRSARTLYRFSIPVPAAPLAEPGGRRGFISAAIKAVVLKVAGKLADYALAKL
                     ALLWETATWKYKGRREGWLSVTGEALGGQQMLPAADLSSLSTTGRNLLFLHGTFSSTT
                     AAFNGLATTRGSRGKTFFDELQDLYGNRIYGFDHFTLSRTPEENVRMLLEALPDRTTT
                     FDVITHSRGGLVLRHLVERRDRFGALADRFAVGRAVLVASPNGGTPLASPDHVTQYTN
                     WLSNVLELFPDNPFTTGVEFVSEALSWIARRLVGSLPGLASMDNNGEIIQALQAAPNP
                     PGQAYSALVANFEPDAGLLQRIIDAGADLFFPTANDLVVPTEGGWRVDPGSGSVPAIP
                     GDRIGCFGVGGNLSQQQPVNHVNFFQDPGTVDFLVRALRGESQLLTPIDCNGDLPTGR
                     RRGAALQKTPPAAVPTVRREEQPTTRPTLPAVQVNPPVVAVEPYPEPDDVFHIALIAP
                     KAGADEAQLIATFRNARVMEHLHTGGSGKTTATCRRGTSDHAPTQWDRIKAGQAHIHG
                     YINGDPAYPQLPDETALQQMGSALFMALFPGQVRRLYDAARSEQVSQRLNLIFTSDIG
                     WIADQSWEFIYDPDRRTFLALEEVNFTRNVLTAIPAERIPARPTMRILVVVAQPLGLG
                     ALSVEEEADVIRSGFRRLLDAGLAEVELLLDATPELLHRALESAAAPIDVLHFIGHGE
                     YNEQTDCGYLIFENQDGGEQRLDSSTLRQIVCRRGIRLVCLNACETGRGGRQDFSRGV
                     AQALIAGGVPAVVANQYPVLDVSATAFSRHFYWALAMGHPIGDAAREARVSVNYAISG
                     EAIDWAVPVVFARNPAQRLCVPRTAAGYERSRRAVVRQRRRAVEDRIKIGIWNAHRMI
                     PHLPDICERLTKAQDRYAFETVSFPAPIGIWRREQEKDQAFVVAETLYDRLKGKPKEL
                     GVETLICMINFPMKDARTRYLYYWRRDPLIVTSTFGLLEQLNEREFTVERMMAHLAAA
                     VVAGIPPHPRRVGPADCPLFYNEQRDIRLIAGRLTFCANCRKQFKDKPAQERLRAAER
                     LLAAYP"
BASE COUNT         1595 a         2467 c         2265 g         1493 t
ORIGIN      
        1 gaccgtcgaa ctggtgagca cgaatgtcga acggggtttc atcgacttct cgcgagtcgc
       61 ctcctgagcg gaaggcatca cagaagcagc actccgaagc ctcacgttca cgatctgatt
      121 caagggcccc agaccacctc tggcacattg gtgcctgcga tcaccgaaaa ggattccgca
      181 ccgagcgtgt aggctcccgc cgggagcagg ccggagaaga actgctctcc aggatctgtg
      241 tccgcgcccg ttcaatgctt gggtcggcgt tttttgaacg ccgcttccag caacgctctg
      301 gcatgaccga tcatcttcgt ctgttctgcc accatctgat tcaaggtcgc catctcggtt
      361 ctctcttaat cgcgcatacc catgaccagc tggtgaacgc tcggccgcaa ctgtcatcct
      421 ctcgaaccaa atgttcactc cgcgtctaat gccgcttata gcacagtgcg tcacactcga
      481 ccatgctcac aggacgtgag gtacgacgta ccgtgatagg agcgcctacg caacttcacg
      541 tggcccgcac ttcgtctacg cttctcttcg tcgccggagt gactcagcat gatacaacct
      601 gcctttcttc cgcaaaaaaa tgtccggaag ggttgacagc gcaacgtagg ataaggtgta
      661 ctcagatgcg gtcacgacgt tccacctcat tggggcccat gtgatcggca acaccagggc
      721 tctcagcgtg gcccaattcc cgaaactcct cgccgggaca ttggcgacct gacagtcact
      781 tcaacgcatc gcaggcctcc cggctcccac gcatctcgac agatgcgcgc ggctcggctt
      841 cgtccgtgac gtgcgggacc acctggccgg tcagagcaca gggcatattc accattcatt
      901 cagcgagaag gaccctcgcg agatgacccg cagtgccact ccggtaatgt cgctctcccc
      961 gaatctggac tttctgcgcg cgatcgcagt tctcctcgtg tacttcttcc acttgttcat
     1021 cacgactggt ccgcgcttgc cggacttcct cgcgcaattc ggcgtcattc tcttttttgt
     1081 tcataccagc ctggtgttga tgttctccct gcagcggatc gacctcaagg ggcagagact
     1141 gtttgcgacg ttctatctac gccgcctgtt tcggatctat ccgctcagca tcgtgtgcgt
     1201 cagtgtcatc atcttgcttc agcttccccg ggctccctgg tggccatgga cacaaccgga
     1261 cacctcgacc attctggcga atcttctgct gtataccgag ttcacctata aacctgtcgt
     1321 gacctcggtg ctctggagtc ttccttatga agtcgccatg tacgccgttc tcccattctg
     1381 ttacctggcc gggaaggcct atgggatcag aggaattctt gctctttggg gtctcgccgt
     1441 ggtgggcggc ttcgtccagc catacatctc ctggcgtctc ggcctggcgc aatttgcccc
     1501 ctgcttcatt gccggagtgg cttgctactt tatggggtat ggagctcgcc ggcgcccgct
     1561 gccattttgg ggctggccac tgatccttct tgccgccgcc ggcattcaag gatttgggag
     1621 ctactacgaa tatgagcagg tctcgcgatg ggtcctgtgc ctcatgatcg gtctcaccgc
     1681 gccgttcttt gccgaattga accggccgat gttgaacaaa gccacggaat tgatcgctcg
     1741 ctattcatat ggaatctatc tgacccatct ccatgcgcaa tgggcggcac tggtcctcct
     1801 caaagatcaa ccggccgccg ttcgatatag cgtcctggtc gtgctcagcg tcggcctgcc
     1861 cgtagcgctc tatcatatgg tggaagcacc aatgatccgg ctgggcgctc gcctggcagc
     1921 gaatttgcca acgaaatccg ttcccgtcgt cagaccggct tcgccgcaac gggcgctccc
     1981 tgcaccggca gaagctgcac cgtacggcag gccctcccag cccgtacggc ccaggccagg
     2041 gcaagcgccg gctgtccgca cgggtaaaag tgctccggct ccggcctccg cgaggtaata
     2101 ccctccgcgt cccttcgtct tcagttcctc cgtgatagaa ccacacccct gtgcctccct
     2161 tcaccttcgg ggtgcacgcg gcatcaattg acaggctcgc gcaccaggcg tacccttcgc
     2221 gcccatggcc cgcacgggtc cagacgttcc ccgatgcggc atgcgacaca ttcgccatcc
     2281 attcaccatc caacgagagg ttttcatgtt gaccagattc ctgttgtgtc ttgtcctggc
     2341 tgcagccacg ctacccaccg cgggacttgc actcgccgcc gaacgcacga acgttgaata
     2401 ctcggccgat caaatcatcg agtctgaaga tggagccacc aaaagccgta tctattcgac
     2461 accgaccaaa gaacgccgcg acatgtctca aggcggcgcc gcgatgacga tgatcacccg
     2521 ccatgacaaa catgtcagct ggacggtcat gccggaagaa aaaatgtaca tggaagcgcc
     2581 ggccactaag caggggcagg ataaatccga tctttccggc taccagattg agcagacggc
     2641 attgggagag gagaccgtca acggtgtcgt catgaataaa agcaagatca tcatgaccgg
     2701 caacgacggg acgaagatgg gcggtttcat gtggaccacg aaagaaggca ttctggccaa
     2761 gattgacgcc ctggccgtcg agaagggaca gaaagcgcgc ttcaagatgg agcagaccaa
     2821 tattcagatc ggcaaacaac cggccgagct ctttgaaatt cccaaggggt tcgaaaagct
     2881 ggatatgggc ggcatgggca tggatatgct gaaagggatg atgggacgct aaggaggcag
     2941 tcgtgacacg aatcacatct tggcatctcg tgtgtgccgt cgcgcttggc ttgtcgggca
     3001 ctcccgtctg ggcagactcc ctgtgtgcgg agaaggcgct acaggcagcg gcagatgcgc
     3061 agttgaagaa ggccgaagag cttgaacggg ccggccaacc acgcgaggcc ttttccgccg
     3121 cgaccaaagc gaacggcgac tgtgtcagcg atactcaacg ccacgaaggg gtacagcaac
     3181 gcactgccaa ggccattggc gcagaagagg aaaagaaggc acgcctggag gacgcgttta
     3241 catggtacgt gcgcgcgaag gcacccgccg atgcgggccg catgcaacgc aggctcgtcg
     3301 aggccaaacc ggacgacatc aacacgctga gccacgccat cgactacttc tcccagcaga
     3361 acgacaaggc gcaggaagaa gcgatgcgca cccgggctcg caaaaacgtc gagcaggccc
     3421 tcgccgagga agaaaagcga tttgcctcat tcagcaggga ttcattgcat gaacttgggc
     3481 gggcgcgcga ttgggcctat tacgccaaaa ccggagagga ccgcattcgc gcgcgggcgg
     3541 cacaacgcgg cgataccctc gcggccgagg acggtcgaaa gttcctccgt ctcgccatgt
     3601 cctattacga gcaggccgac cgtccggacg gcgtcaaaaa aatacgcgag aaggcgcgaa
     3661 tgctggcgaa gcggcatgaa gccaaaggtg aaggcgagat cgcggcggag ttttacgcga
     3721 tggccggcga cgacaagcag gccgacaccg tccagaagca cactgagcag cgccagacgc
     3781 aggccgaaga agggcgcaag aagaccttca aaaaagagca ggcggatctg gagaaggccc
     3841 tcggcttctg agcagcccct cctcgcgaga aactcatgct cgcgttcttc gcgtgcaggc
     3901 caccgatggc ctgcgtgtgt gcttgctgcc tcaacgcccc ccttgcctga tcgtcccggt
     3961 tatgggataa gcgcggcgaa caatcctcgt catgcagaga ttgtaacgga tccttcgtcg
     4021 gcacatccgg atgaccggcg ctccacggga gacgaccgac gaggcaaccc ttcgtcaaca
     4081 ctacgatcag acgtcatcag gcggcacgag accagcagga gcacattatg gcgaaaaaac
     4141 aatcgggcac ggtgagctgg gcgacatcgg cagagtggga cgttcgcaca ctggagcccg
     4201 ctcgtggcgg acggcggggc gcgaccgaac ccccggaccc ctttctggtg aatctcacgg
     4261 caaccaaacg ctgggaagtc gagcagactc tcacagcgac gcccaaagcc agacgcggcg
     4321 agaccgcccc tgcgccgccc ctcaccctgg atgtcgaagc cgacccggac gacgtctata
     4381 tcgtcatgac gcgttatgcg tcaggagcca tccgcttcca catgccgaac gaaccggccc
     4441 ggcgcggacg acggaggagc gcacgaaccc tctaccgatt ttcgattccc gttcctgccg
     4501 cacctctcgc cgagccaggc ggccgccggg gattcatcag tgccgccatc aaggccgtgg
     4561 tcttgaaggt cgccggcaaa ctcgccgatt atgcgctcgc caaactcgcc ttgttgtggg
     4621 aaaccgccac ctggaaatat aaaggacgcc gggaaggatg gctgtccgtc acgggcgaag
     4681 cgcttggtgg ccaacaaatg ctcccggccg ctgatttgtc atcgctcagc accactggcc
     4741 gcaatctgct cttcctgcac ggcacctttt ccagcacgac ggccgccttc aatggattgg
     4801 ccacaacccg gggcagccgc ggcaaaacat tcttcgacga gctgcaggat ctctacggca
     4861 accgcatcta tggattcgac cacttcaccc tcagccgcac accggaagaa aacgtgcgca
     4921 tgttgctgga agccctgccc gatcgcacca ccaccttcga tgtgatcacc cattcgcgcg
     4981 gcggattggt cctgcgccac ctcgtggaac gtcgtgaccg gttcggggcg ctggcggacc
     5041 gcttcgccgt cggccgggcc gtgctggtcg caagcccgaa tggcggcact ccactcgcat
     5101 caccggacca tgtgacgcaa tacaccaact ggctgtccaa cgtgctcgag ctgtttcctg
     5161 acaatccctt cacgaccggt gtggaattcg tgagcgaggc gctgtcgtgg atcgcccggc
     5221 gactggtcgg tagtttgcct ggtctggcct ctatggataa caacggcgag atcatccagg
     5281 cattacaggc ggcaccgaac ccgccaggtc aagcctattc cgccctcgtc gccaatttcg
     5341 aaccggatgc gggcttactt caacggatca tcgatgcggg cgcggatctg tttttcccca
     5401 ccgccaacga tctcgtcgtc ccgactgaag gcggatggcg agtggatcca ggcagcggct
     5461 ccgtccctgc cattcccggg gaccgcatcg gttgtttcgg agtcggaggg aatttgtctc
     5521 agcagcagcc ggtgaaccat gtgaactttt tccaggatcc cggcacggtg gattttctgg
     5581 tccgcgcgtt gcgtggtgaa tcacaattgc ttacgccgat tgactgcaat ggcgacctgc
     5641 cgaccggacg acggcgaggt gcagcccttc agaaaacacc gcccgccgct gtaccgacag
     5701 tccgccgcga agaacagcca acaacgaggc cgacgcttcc cgcagtgcag gtgaatccgc
     5761 cagtcgtcgc ggtcgagcca taccccgaac cagacgacgt gtttcatatc gccctgatcg
     5821 ctcccaaagc aggcgcggat gaggcgcagc tcatcgccac cttccggaat gcccgcgtca
     5881 tggaacacct gcacaccggc gggtccggca agacaaccgc cacatgccgc cggggaacca
     5941 gcgatcatgc gccgacgcag tgggatcgta tcaaggccgg acaggcgcac attcacggct
     6001 atatcaatgg tgatcccgct tacccgcaac tcccggatga gaccgcgctc cagcaaatgg
     6061 gtagcgccct cttcatggcc ctctttcccg gacaggttcg ccggttgtat gacgcagcgc
     6121 gatccgaaca ggtcagccag cggctcaatc tgattttcac ctccgacatc ggctggattg
     6181 ccgatcagtc gtgggaattc atttatgacc cagaccggcg cacgttcctc gcattggaag
     6241 aagtcaattt cacgcgcaat gtgctgacgg ccattcccgc cgaacgtatt ccggccagac
     6301 ccacgatgcg gatcctcgtc gtggtcgcgc agcctttggg actcggcgcc ctgtcggtgg
     6361 aagaagaggc cgatgtgatc cgcagcggat tccgccgcct gctcgatgcg ggactggccg
     6421 aggttgaact cctgctcgac gccacgccgg aattgttgca ccgggcgctg gagtctgcgg
     6481 ccgccccgat cgacgtgctg cacttcatcg gacacgggga atacaacgag cagaccgact
     6541 gcggatactt gatcttcgag aatcaagacg gcggcgaaca gcgattggac tcctccacgc
     6601 tccgtcagat cgtctgccgg cgcgggatac gtctggtctg cctgaacgcc tgcgaaaccg
     6661 gccgcggcgg gcgacaggat ttcagccgcg gtgtggcgca ggcgctgatc gccggcggcg
     6721 tccctgccgt ggtcgccaat caatatccgg tgttggatgt gtcggccact gccttctccc
     6781 gccacttcta ctgggccctg gccatgggac atcccatcgg cgatgcggcc cgcgaggcgc
     6841 gcgtgtcggt caactatgcg atctccggag aagccatcga ctgggcagtg ccggtcgtct
     6901 ttgcgcgtaa tcccgcacaa cggctctgcg tgccgcgcac cgctgccggg tatgagcgga
     6961 gccgcagggc ggtggtacgc cagcggcggc gcgcggtaga agaccgcatc aagatcggca
     7021 tctggaacgc gcatcgcatg atcccgcacc tgcccgacat ctgcgagcgt ctcaccaaag
     7081 cccaggatcg gtacgccttc gagaccgtat ccttccctgc tcccatcggc atctggcgcc
     7141 gggagcagga gaaggatcag gcatttgtgg tcgccgaaac gttgtacgac cggttgaagg
     7201 gcaaaccgaa agagttgggc gtggagacgc tcatctgcat gatcaacttt ccgatgaagg
     7261 acgcgcgaac gagatacctg tattactgga ggcgagaccc gctgatcgtc acgtcgacct
     7321 ttggattact ggaacaattg aacgagcggg agttcaccgt tgagcgcatg atggctcatc
     7381 tggcggcggc ggtcgtcgca ggaatcccgc cgcatccccg gcgggtggga cctgctgact
     7441 gtcccctctt ctacaatgaa cagcgggaca ttcgtttgat cgcgggccgg ctcacgttct
     7501 gtgccaactg tcgaaaacaa ttcaaagaca aaccggcgca ggaacgcctg cgggctgccg
     7561 agcgacttct tgccgcctat ccgtagacgg cacattggtc attcggactt gtgacactcc
     7621 cgcacggcct tgagcaaatt ctccggcgtg ccgatgtcaa ggtagcgcgc gccggggact
     7681 ttcacgctct atgtataagc ctgcatcgtt ggcaaatgag cccctgagca gcgcgatttt
     7741 gagtgggaaa tgaaaactcc gggagtctga atttccgcga cgggagggac cattagcggt
     7801 agattattgc tgtgtctacc
//
LOCUS       DAOQPD010000115         7686 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_5285_length_7686_cov_20.412004, whole genome shotgun sequence.
ACCESSION   DAOQPD010000115 DAOQPD010000000
VERSION     DAOQPD010000115.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 7686)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7686)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7686
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5285_length_7686_cov_20.412004"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(355..555)
                     /locus_tag="PK063_17445"
     CDS             complement(355..555)
                     /locus_tag="PK063_17445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98890.1"
                     /translation="MSKVEAIEQQIEKLSSDELAAFRRWYVAFDAETWDRQFENDVKA
                     GRLDALAEKALRAHTSGQSRPL"
     gene            complement(847..1392)
                     /locus_tag="PK063_17450"
     CDS             complement(847..1392)
                     /locus_tag="PK063_17450"
                     /inference="COORDINATES: protein motif:HMM:NF015438.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HMZ98891.1"
                     /translation="MKLLSVQVGRPRTVRWHGKVVSTGIYKEPVEGRLPLQLFNLKGD
                     EQADLTVHGGREKAVYVYPSEHYPFWRKEYPDLPFHPGWFGENFTVEGMDERTVCIGD
                     QFRIGGALVVVTQPRMPCFKLGIRLGKPDAVKRFHASGRCGFYLGVLQEGEVGPGDLW
                     EQVARGDEQMTVIESYRLMTQ"
     gene            1578..1904
                     /locus_tag="PK063_17455"
     CDS             1578..1904
                     /locus_tag="PK063_17455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YnfA family protein"
                     /protein_id="HMZ98892.1"
                     /translation="MLITQSIALFVLAGLFEIGGGYLVWQWWRNGSHWSVGLLGAVIL
                     ILYGIVPTYQPSHFGRVYAAYGGWFIILSILWGWLVDHVEPDRFDIIGAMVCLVGVTV
                     IMYWPR"
     gene            2272..3168
                     /locus_tag="PK063_17460"
     CDS             2272..3168
                     /locus_tag="PK063_17460"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98893.1"
                     /translation="MANQDETLKHIWKSGFPFQLKIEDEVRRTHSTHNWLIATREHPW
                     TNKETESSGFIDLVLMHDHFVTYRMVIECKRVKADDRRQLHWLFLIPEGEKQETPLAS
                     CLQIGGTSPMNARIGEANVSQQEWDHVRIWENVNIFPKSFESSICVLPSDDSKSQPIL
                     ERLAAGVIDSVEGLGDEEILVHQSQFQVDRLIAFLYPVIVTNAEIAICSFDPSKVSIL
                     DGTLDASAATITTVPFIRFRKSIATTFPEGTFSNLKEANEARELTVFVVNAGALPSLL
                     TNWRMASRDLSGRYAIQNHLQR"
     gene            3214..3936
                     /locus_tag="PK063_17465"
     CDS             3214..3936
                     /locus_tag="PK063_17465"
                     /inference="COORDINATES: protein motif:HMM:NF025056.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003953 - NAD+ nucleosidase activity
                     [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HMZ98894.1"
                     /translation="MPTHDTFLSYASEDNDFAFQIAYGLRANGISVWFAPLMLKVGDR
                     LLDSVELGMAESRTGTLLLSPTYLHKGWTSYEMDILIRQHIEGTKPLLPIWHNASKKQ
                     VDAKHSGLGGIVAITDTSSATEVVFKLIEGLSSGAPSRAVVPIWEDPTYRFLEGLAEV
                     NLQSGEGAATTIFEFLLHAKESQYPLWIGGRVFTKNQLLLHVAQLLGPVPDRVKSWVH
                     EDGYRKLWEMCVENDLNPHNFY"
     gene            complement(4259..4750)
                     /locus_tag="PK063_17470"
     CDS             complement(4259..4750)
                     /locus_tag="PK063_17470"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98895.1"
                     /translation="MPDRFHPDEALKNEAISQAMEGDFIGARQTGAKIAARQDFLEAW
                     MYILHLQRDRGDVIGIKETILSCPNPSWLQGHSYAELARHFAKIGNKTAAIEIAKLLG
                     RSGEMMVVYLSAPVDLILKGDFAGAREAVAKVEDEQLRNQLNALVDREEQIRSGPTQQ
                     SVL"
     gene            5121..5717
                     /locus_tag="PK063_17475"
     CDS             5121..5717
                     /locus_tag="PK063_17475"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="VPLPA-CTERM sorting domain-containing protein"
                     /protein_id="HMZ98896.1"
                     /translation="MKTAWMALLALCAVAQTGEAALIGTDVMFQSVFQATSTSPEFKL
                     TSLNTVTVKEPGVEFPSLKALQVSNPSGLRLVDIAINIGDTFIDMNFTNSAPDFRFAS
                     GFRNGYKLTFDNAAMPSIRQALIDRTVTTLGLSDSDVTFSGNTLQVNVESLPFNTSTF
                     ARINLTVEGGPSPVPVPAAAWLFGSGLAALVALKRSGA"
     gene            complement(6119..7003)
                     /locus_tag="PK063_17480"
     CDS             complement(6119..7003)
                     /locus_tag="PK063_17480"
                     /inference="COORDINATES: protein motif:HMM:NF020252.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDOD domain-containing protein"
                     /protein_id="HMZ98897.1"
                     /translation="MKDNKTAVLRKLTEDSAMQLLEGVTLPPQPGTLLDINRERAKAE
                     PDVAAVAGIIERDLSVAAAVLKTINAPWFELPKKVESVRQAVVLLGMPNVVNVVIALA
                     MKSELQGNNQAGIDRFFDEANDTAMVLSSVMREVPVMSTDKAYLLGLFRDCGMPILLQ
                     RLPQYAEVLQEAAKRPEQSLPDIEDARLKTDHAVVGALMSRHWHLPEEIGTIILNHHR
                     TRELFGGKAQKLASSEESIRTVIAVLAMVDCICHRLRTRNDSPEWAAIGEKVLAHLKL
                     DQAEFEHLAWDQQDRFAA"
     gene            7397..>7686
                     /locus_tag="PK063_17485"
     CDS             7397..>7686
                     /locus_tag="PK063_17485"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98898.1"
                     /translation="MRTTVLSSELAHSTSRIGFMRSVFELLGIVLVRFRPVQRMWGAW
                     LIAVNAACLLFITHIEAQVALAAVGLALLAQALIYQRTRFIRLLGVTHLIWVP"
BASE COUNT         1757 a         2193 c         2022 g         1714 t
ORIGIN      
        1 cgcagtttgg ggcaaaccga gcccctcttg gtgtggggag gtaggaagga aaacctgaaa
       61 agaaccttgc ggcgggataa agaccggttg gctgcctgcc ttacttctgg ataagtttgt
      121 cgtactccgc gtgtgtgccg atccagaacc agacgatgcc gtcaggcgct tccactccaa
      181 ccgctcgata ctgaagacct gcacgtgcag accaaaaccg gcctacttgc ttgaaatgca
      241 gcgacggatg tcgagggttg gcctttaata attcaaacgc gcggtcagct tgctcacgga
      301 ttgtagcagg aagggcatta taacaggccc aaaattccgg tgaggtatga tgaatcaaag
      361 cggcctagac tgtcctgagg tatgggcacg aagagctttt tcagcgaggg catcaagcct
      421 tccggccttc acatcatttt cgaactggcg atcccatgtc tctgcatcaa atgccacata
      481 ccatcggcga aacgcggcaa gttcatcgga ggaaagtttt tcaatctgct gctcaatcgc
      541 ttctactttg ctcatacatc acctacattt tccaggatca gagacaacct ctgtctctct
      601 gctgtccatc agcaatcaga atgttcgtat cctagcatta gaaaaggatg ccgtccaact
      661 tccaatacga tcacccagcc ccggtttagg ccgatggggc aagagaaatg gcggcctgat
      721 gatctcccca ctgctcgcac aacgcgcggt cgcagactct ccctcgttgg acgcgcgcag
      781 tttggggcaa actaagccct gcttgttgtg ggaagttgag agatgaaaag tgaactgggc
      841 ttgccgctat tgggtcatca gccggtagct ttcgatgacg gtcatctgtt catcaccccg
      901 ggcgacctgt tcccagagat cgcctggacc aacctcccct tcctggagca cgccgagata
      961 gaagccgcag cgaccgctcg catggaaccg cttcaccgca tcgggcttgc cgagtcggat
     1021 gccgagtttg aaacaaggca tgcgcggctg ggtcaccacg accagggcgc cgccgatccg
     1081 gaattgatcg ccgatgcaca ccgtccgttc gtccatcccc tcgacggtga agttctcgcc
     1141 gaaccatccc gggtgaaacg gcaggtcggg atattctttc cgccagaacg ggtaatgctc
     1201 cgacggatag acgtacaccg ctttttctcg cccgccgtgt accgtcaggt ccgcctgttc
     1261 gtcgcctttg agattgaaga gctgcagcgg gagacggccc tcaaccggct ctttgtagat
     1321 cccggtcgag acaactttgc catgccatct gacagtgcgg ggacgtccga cttgcacgga
     1381 gagaagtttc atggaagcct cctctgaacg taaggcgctg cccccttgga cttgcacgtc
     1441 cgttgtcgtc atgatctcat accgccccct cgcctcgcca tcgaaccggc cgggctcggg
     1501 tacgtcacct ggagcgcgtg tcgtcaattc gaacgaaacg tcgatttctt accagaagaa
     1561 aaacaatgag agaacccatg ctcatcacac aatcgatcgc cttgttcgtg ctggcgggtc
     1621 tgttcgaaat cggcggcgga tacttggtct ggcaatggtg gcggaacggg agtcactgga
     1681 gcgtcggcct cctgggcgct gtcatcttga ttctctacgg catcgtgccg acctatcagc
     1741 cgtcgcactt cggccgggtc tatgccgcct acggcggctg gttcatcatc ctctcgattc
     1801 tgtgggggtg gctggtcgat cacgtggagc cggatcgatt cgatatcatc ggggcgatgg
     1861 tgtgtctggt tggcgtgacg gtgatcatgt attggccgag gtgagagggg gaaagaggct
     1921 ggcctggccg tcctccatgc tcgcgcaacg cgcggtcgaa gactcccctc gttggacgcg
     1981 cgcacgcagg gaaccggcca ggccgcctca gagggcgaat gtaatccaat caataaacaa
     2041 acaatagacc cagctagaac gaaaaagtag aatcctcagt tgattatttg ggagaactgt
     2101 atgaaaggcg agtttaagga aatcggccac tcaggaaata agatcacctt tgagatattg
     2161 accaatgctg agggccaccg cggctatcag acaagaatta ccgacagctc ccaggcgcct
     2221 atagtcatga ccgaggcata cgcttttcca ggcgggagaa ggcaaagcta aatggccaat
     2281 caggacgaga cattaaagca catctggaag tctggctttc catttcagtt aaaaatcgag
     2341 gatgaggttc gaaggactca ttcaactcac aattggttaa tcgcaacgcg cgaacatccc
     2401 tggacaaata aagagactga atcctccggc ttcattgacc ttgtcctgat gcacgatcac
     2461 ttcgtgacgt acaggatggt cattgagtgc aaaagagtaa aggctgacga tcgaagacag
     2521 ctccactggt tgttcttgat tcccgagggc gaaaagcaag aaacaccgtt ggcttcatgc
     2581 ttacagattg ggggaacctc accaatgaac gcgagaatag gtgaggcaaa cgtaagccaa
     2641 caagaatggg atcatgtgcg aatatgggaa aacgttaaca tctttccaaa atctttcgag
     2701 tcctcaatct gcgttcttcc tagtgacgac tcaaagagcc agcccatctt ggaacggcta
     2761 gctgctgggg tcattgactc tgtcgaggga ttaggggacg aagagatttt ggtccaccaa
     2821 tcacaatttc aggtcgaccg cttaatcgcc ttcctctacc ctgtaatcgt caccaatgca
     2881 gagatcgcca tttgcagttt tgatccaagc aaagtcagca tcctagatgg aactcttgat
     2941 gcgtcggcag ctaccattac gacagtcccc ttcattcgat ttcggaagag tattgcaaca
     3001 acattcccag aaggcacctt ctccaattta aaagaagcaa atgaggccag agaactaacc
     3061 gtatttgtcg taaatgctgg cgctctacca tcgctattga cgaactggag gatggcatcg
     3121 cgcgacctaa gcggacgata tgccatacag aaccacctac aacgataacc atggccaagc
     3181 ctaccctcat tgtttgacct agaacacaat cctatgccta cgcacgatac ctttctttcc
     3241 tatgcgtccg aggacaacga ttttgccttt cagatcgcat acggacttcg tgcgaacggt
     3301 atctcggtct ggtttgctcc gctcatgctc aaagttggtg atagattact tgactctgtc
     3361 gaactaggca tggctgagtc tcgcacagga acgctcctgc taagtccaac ttacctccac
     3421 aaagggtgga cctcctacga aatggacatc ctcattcgcc agcacatcga aggaaccaaa
     3481 ccgctcttgc ccatctggca caacgcctcc aagaaacaag tagatgcaaa gcacagcggg
     3541 ctaggcggga tcgtcgctat cacagacacc tcgtctgcga ctgaggtcgt tttcaagctt
     3601 atagaaggac tgtcgagcgg tgcgcccagt agagccgtcg taccaatctg ggaagatccc
     3661 acctataggt tcttagaagg tctcgccgag gtgaaccttc aatccgggga gggggccgca
     3721 acaaccatct tcgagtttct gctgcacgcc aaggagtcgc agtacccact atggatcggg
     3781 ggacgtgtct tcacgaagaa ccagctgtta ttgcacgtgg cccagttgct cggcccggtg
     3841 cctgatcggg tcaagagttg ggttcatgaa gacggatacc gtaagttgtg ggagatgtgc
     3901 gttgagaacg atctgaaccc gcacaacttc tactgagact agttgatact gcggggctaa
     3961 cggacccctt cgattgaata aaccgccacc aatgaagcaa tgggtcatcc tgagatggct
     4021 ccggtataac agataggaca aggcctgtga tcacacattt tcctacccgg cacagagact
     4081 cgcatacggc accttgccca tttcttgccc cgctttttcc agagcagagg gacagcgaga
     4141 atcgtgagcg gcaccagtag caagcgtccg gttgactggc tgcaagggat gcgccgaggg
     4201 ggttaggctt tcgagtagtc gcgtatcgac tctgggtcga ttgcgccgtg gtcttcagtt
     4261 acaaaacaga ttgctgagtg ggcccactgc ggatttgctc ctctctgtcc accagggcat
     4321 tcagttggtt tctcaattgt tcatcttcaa ccttggcgac ggcttctctg gcaccggcga
     4381 aatcaccttt gaggatcaga tccacgggcg ccgatagata caccaccatc atctctccgg
     4441 atcgcccgag gagcttcgcg atctcgatcg ccgcagtctt gtttcctatt tttgcaaaat
     4501 gtcgggccaa ttcggcatag ctgtgacctt gcaaccagga tggattaggg cacgagagga
     4561 tagtctcctt aattcctatg acgtccccgc gatcccgctg caggtggagg atatacatcc
     4621 acgcttccaa aaagtcttgc cgcgccgcaa tcttggctcc ggtctgccgc gcgccaataa
     4681 aatcaccttc catcgcttga gagatcgctt cgtttttgag cgcttcatcc ggatggaaac
     4741 gatcaggcat gggcttcctc acttgcgtca ccttgctgaa tgacaccatt caagcctagc
     4801 accctacgct gaaaagtata gtagtactct ccctgttctg ccgtcggtct catgtcctca
     4861 aaactgacca gaaatggtgc cgggaatcat gtatcggcag ctggaacgga acacggctta
     4921 tgcaccatgc tatgtgcggc ccaatatcaa tgattcctga ctggcctgcc atggaggaac
     4981 tgcaacgatc aacagtgcct gagaccactt tactcacttg acagagccct cgaaccacta
     5041 tagattccat ttcggttact acttagtcga gatcaaacca ctcaggttgg acaatcggca
     5101 cgctaagaga aaggtcttct atgaaaactg catggatggc tctgttggca ttatgcgcgg
     5161 tcgctcagac cggcgaggcg gcgttgatcg gaacagatgt aatgttccaa tcagtctttc
     5221 aggccacctc cactagtcca gaatttaagc taacgagcct caacaccgtg acggtcaagg
     5281 agccaggcgt cgaattcccc agcctcaaag ccttgcaggt cagtaatccg agtgggctcc
     5341 gcttagttga tattgcgatc aatataggag acacgttcat cgatatgaac tttactaatt
     5401 ccgcccctga cttccgattc gcatcaggct tccgcaatgg atataagctc actttcgaca
     5461 atgctgcaat gcccagtatc aggcaggcac tgatcgatcg taccgtgacc acgcttggct
     5521 tatccgacag tgacgtcaca ttctccggca atacgcttca agtcaacgtc gagagccttc
     5581 cgtttaacac ctccacgttc gcgcgaatca atttgacggt ggaaggcggc ccgagccccg
     5641 tccccgttcc ggctgcggcc tggctttttg gatctggcct tgctgccttg gttgcgctga
     5701 aaaggagtgg tgcttgatag atggtcgagc ccgtggcggc gggatcaagg cgacgccaag
     5761 cagacagcgt ggcttagtga ccggcccagg atgcggccac gcgattgagt ggctcgtgtg
     5821 aatcgctcac agaccgcata ggagctggaa tcactccaaa cgcgtgcgca acggggctcc
     5881 cgagcggtga agatgcctgg gtgcggaggt tggcgaagca gtctggaatg gaatcgaccc
     5941 tccggccacg ggacgaccga atgggttctg gaagagctca ggaagagaaa acggggacct
     6001 tctgaatttc ttctgagttc cggaatggtg ctcggtgacg ctcccccgca cgcagcgcgt
     6061 attgcccgcg cctcgacagg aacctcgccg atcttcagag aaaggcagta cccccgggct
     6121 aggccgcgaa ccgatcctgc tgatcccaag cgagatgctc gaattcggct tgatccagtt
     6181 tgagatgcgc caggaccttt tcgccgatgg cagcccactc cggtgaatcg ttgcgtgtcc
     6241 ggagtcgatg gcaaatacag tccaccatcg ccagaaccgc gatcacggtc cggatacttt
     6301 cttcggacga ggcaagcttc tgcgcctttc cgccgaacag ctcgcgagtc cggtgatgat
     6361 tgagaatgat tgtgccgatt tcttccggga gatgccaatg ccggctcatg agcgccccca
     6421 cgaccgcatg atcggttttt aagcgcgcat cttcgatgtc cggcagcgac tgctccggcc
     6481 ttttcgccgc ctcctgcagc acctccgcat actgcggaag gcgttgcagc agaatcggca
     6541 tgccgcaatc ccgaaagagc ccgagcagat aggctttgtc cgtcgacatg acgggcacct
     6601 cacgcatcac gctcgacaga accatcgccg tgtcgttcgc ttcgtcgaag aagcggtcta
     6661 tccccgcttg attgttcccc tgtagttcac tcttcatggc cagggcgatt acgacgttga
     6721 cgacattggg catccccagc aacaccaccg cctggcgcac cgactcgacc tttttcggca
     6781 actcgaacca cggagcgttg atggttttca acaccgccgc cgccacactc agatcccgct
     6841 cgatgatgcc cgccacggcc gccacatcag gctctgcctt ggcccgctcg cgattaatat
     6901 caagcaacgt ccccggctga ggcggcagcg tcaccccctc caggagctgc atggcagaat
     6961 cttccgtcag tttccgcaac accgccgtct tgttgtcttt catcgcgtat ccttgccgac
     7021 atagaataat gttctttatc ggctcaaaaa tggatctctg tagcccaatt cctcgccccg
     7081 catgaaaaga taaccaggga ccccctcaat gacttcagag ctttagctcg gtgtttggtt
     7141 atcctccccc acgcacatcg agtatttctc gtgacctacc gtaagacgtt tcactccact
     7201 agtggattca ctcttacatc acggcgcttc ggcacgcgaa tccggacgcc tggataagcc
     7261 aacgtaccct cgccgacccc tgctaagaga atcagactcc cggataagac accaagagaa
     7321 atgtcccgta gagtgggaac cgttgttgag cagaacaccg ggtgcggtca cgcgcacctg
     7381 caccaaggag gacgatatga ggaccactgt actatcatcc gagctggccc actcaacgag
     7441 tcgaatcggc tttatgcgtt ctgtctttga actgctcgga atcgttctgg ttcggttccg
     7501 gcccgttcaa agaatgtggg gcgcgtggct cattgccgtc aacgcggcct gtctgctgtt
     7561 catcacgcac attgaagctc aggtcgccct cgcagccgta ggcctggcgc tactcgccca
     7621 ggcgctgatc tatcagcgca cgcgcttcat tcggctgctc ggggtgacac atctgatctg
     7681 ggtacc
//
LOCUS       DAOQPD010000116         7452 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_5545_length_7452_cov_20.768690, whole genome shotgun sequence.
ACCESSION   DAOQPD010000116 DAOQPD010000000
VERSION     DAOQPD010000116.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 7452)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7452)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7452
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5545_length_7452_cov_20.768690"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..699)
                     /locus_tag="PK063_17490"
     CDS             complement(<1..699)
                     /locus_tag="PK063_17490"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98899.1"
                     /translation="MSSHQSSDRPEPRKSGIHDADLDGLAISRPAPGGIPSSGGRRWR
                     WLTLAVLLAVAGLAWSTAWLRPDQRVEVVPVVRMPSGSGAGLAATGYVVAQRQASIAS
                     KGTGRLIYFGVNVGDRVKEGQLIARIEHDDMDALYRQALARLGVARAQLGAAKPELEE
                     ATLSFERVKTLLEKSFVTKSEFDMASARLRRAAAAVKSAEAAVTAAEAERQNATVQLE
                     NTSIRAPFDGVIVKK"
     gene            complement(780..2000)
                     /locus_tag="PK063_17495"
     CDS             complement(780..2000)
                     /locus_tag="PK063_17495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY-associated TM helix domain-containing
                     protein"
                     /protein_id="HMZ98900.1"
                     /translation="MPSESIPVAARQAAQAGVRDRRARVWRTWWVQAHLYLGLTTGAL
                     LVVFGLTGSILVFFQEIDEWLNPALLTVDATADGQNSYRPIGEILAAAEQAAAPGSRI
                     TQVYGATKPERVMAVYMEEPSKAWQRIFVDPYRARVTGVRSYGPDEWVPKYLMDAIFA
                     LHYQLFVGMTGVTLAAIAAWLLILSLVTGVIVWWPVNGQWRHAFVIRRPFALFRLLFD
                     LHKTVSLYLCLAIGAVLLSGAYMNWAEPIIWITQVLSPATRGPAQSAPSAVEDGAHPI
                     SPQRAVELAAAIYPEGRLTSIAMPEDATGVYQVGRQGVPGLSAFWSERIVSVDQYSGS
                     ILDVRAPDTRRSAGETFLDWQWPLHSGQAFGIPGRLLVCASGLACPVIYATGFLMWWR
                     KRRGRARRSLVPAS"
     gene            complement(2210..2644)
                     /locus_tag="PK063_17500"
     CDS             complement(2210..2644)
                     /locus_tag="PK063_17500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98901.1"
                     /translation="MVVRLKLYRVFVVNELLHIMSLRGRTGRAPSLLFFVACLLVAIR
                     VAAGFVCHTCFIDFEKPTSRSFHLHAGGDRDPCHHGQAEASPLTTWACTVTQDETAFI
                     LPEIPRLPLVVSEFVPLVLLLLSYRTLFQIAAHGRGPPVPLS"
     gene            complement(2802..5150)
                     /locus_tag="PK063_17505"
     CDS             complement(2802..5150)
                     /locus_tag="PK063_17505"
                     /inference="COORDINATES: protein motif:HMM:TIGR01783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_function: GO:0015343 - siderophore-iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent siderophore receptor"
                     /protein_id="HMZ98902.1"
                     /translation="MKSTDSCQNASRSFIPLRRGSAGIGRIVAVAGLTLLTACIGPHK
                     PVATDKTSATPVAAPAQGESTGESGGDKAAQARQSPPALPVPLPVPVPAEDLAGTGAS
                     TRDDAPVVDVKPVHIVAQAESYHVTNTVTATKTDTPIMDTPVSVKVVPQQVMRDQQVV
                     RVDQALKNISGVISGAEGDMQFNMRGFDQFNFYRDGYPFQSQWFHGEDLTNIERVEVL
                     KGPGSILYGRAEPGGIINFVTKQPLDQPYYSLQQQVGSYGWYRTNADLTGPLTANNSV
                     SYRLNIGYQTNQTFQQFGGNERLIVSPQVRWRITDHTTSTLKYEYSDISLTGKGNIPL
                     LGNRPAPIARELNLGERWNLQNDKYHLVSLITEHAFNDAWSIRHRFNFSNHQLTLTGQ
                     NVGNAAANGDVSRFFFAQNTDGRDYTRNVFNALELTGHVTTGRIKHTLLFGGDYLHND
                     IRATMAGFTPATDDVINIFNPVHTAGPPVIAPGDVTKYTWSLPWFGLYAQDQIELPYH
                     IHILAGFRYDNAKTSTSNENLGVRTPTIKDTNERISPRAGVVWRPVPEFSLYGSYKEN
                     FGASNTFTAGSVVPLPPQTAQQWEVGAKTELFGGRFIGSLAYFDLTKQNLPVFFPGET
                     RAVGEGESRGVEFDVSGEILPGWSVIGAYAYTPFAKTTKDDPALGTMGKRLNNAPVNS
                     GSLWTVYQFQEETLQGLRVGVGVQGVGERQIGFGETAQAPGYVITNLMASYHWRVGTA
                     RYTAQLNVDNLLDKSYIGQVFSYGPTYYGMPRFFMGSIRMEF"
     gene            complement(5377..5781)
                     /locus_tag="PK063_17510"
     CDS             complement(5377..5781)
                     /locus_tag="PK063_17510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98903.1"
                     /translation="MKPARPFMPLSGSRGRGQRHAVLLALFLIGIRLVAGFLHVSCFN
                     EMERPSARSFHLHAGGDRVPCHHGKAPTSPLSDWACSVNQDESAYILPEVPLLPLVAA
                     LFLLFLLFRVSFGSRSAIVPHGRGPPRHLLVS"
     gene            complement(5944..>7452)
                     /locus_tag="PK063_17515"
     CDS             complement(5944..>7452)
                     /locus_tag="PK063_17515"
                     /inference="COORDINATES: protein motif:HMM:NF012801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HMZ98904.1"
                     /translation="TMPGTNTVGGFADTKNYNIMSKFGATFGDHRFQLTFNRKQSWQD
                     TNYLVDPNVDALPRTFARYVPGLSLADQPKLTNTQVSADYTHPHLFLDSRVHLQGYYR
                     TQQTRFPTLDSRLFGGTDVLQGYNQSDVLGTRLDITTPIPIYGKPEIVWGMDFSSQHG
                     AQSSTLYDQSVFDGSGGRVFSKSGEVASSPSRVFNSTAVFAQGEWTPLAALVLRGGVR
                     YERVKVTSSDFTGNGSFLAASAIEFDTTVFNAGFVYHLLDPLDLFFNFSQGFNVPVGS
                     IDNALGNVPPGTAISLQRLQPQRVNNYELGLRGKWSKVQASVSGYISKSSLGLNFDQF
                     TNSLRRAPQTIYGVEATLDLQPIERVRLGGTYTFVEGDQKVGFNPDVRVPLNGFSIAP
                     QKITAYLEHLTVPEWDWRNRVQVLYSGSRSRSLTAFNSGIDPTADPFGQTEYFLVDLI
                     STVKAGPGTLRFGVENLLNKQYATPFNQISFTNSFYFAGRGTTASIGYSIYY"
BASE COUNT         1563 a         2353 c         2143 g         1393 t
ORIGIN      
        1 tttcttcacg atgactccgt cgaacggcgc gcgaatgctc gtattctcca gctgcaccgt
       61 ggcgttttgc cgttcggctt ctgccgcagt caccgccgcc tcggccgact tgaccgccgc
      121 agccgcgcgg cgaagtctcg ctgacgccat gtcgaattcc gacttcgtga cgaaggactt
      181 ctccaggagg gtcttcaccc gctcgaaact cagcgtcgcc tcttcgagct ccggtttggc
      241 ggcgcccaat tgtgcccgcg ccacgcccaa ccgggccaag gcctgccggt acagcgcatc
      301 catatcatca tgctcgatgc gcgcgatcag ttgcccttct ttcacccgat cccccacgtt
      361 gacgccgaag tagatcagcc gccccgtgcc cttggaggca atcgacgcct gccgctgcgc
      421 gaccacatac ccggtcgccg ccaggcctgc cccgctcccg gatggcatgc gcaccaccgg
      481 aaccacttca actcgttggt ccggtcgaag ccaggccgta ctccaggcca agcccgccac
      541 agccagcagg accgccagcg tcagccaccg ccaccggcga ccaccggaag acggaatccc
      601 accaggcgcg ggacgagaaa tcgccaaccc gtctaaatcg gcatcatgaa tgccggattt
      661 gcgaggctca ggacgatcag atgattgatg actggacacg ggaacctcct ccatggaacg
      721 gcagtgagtc gtgccgctcc ttctcgtttc cttcgcactc taatctgcca caccgcgggc
      781 tacgaggccg gtacgagcga ccgacgcgct cgcccccgtc gcttgcgcca ccacatgaga
      841 aacccggtgg cgtagatgac cgggcaggcc aggccgctcg cacagaccag caagcggccg
      901 ggtatcccga acgcttgccc cgaatgcagg ggccattgcc aatcaagaaa ggtttccccg
      961 gcgctccgcc tcgtatcggg ggcccgcacg tcgagaattg agccactgta ttgatcgacg
     1021 ctcacgatcc gttccgacca aaacgcactg agccccggca ccccctgcct gccgacttga
     1081 tacactcccg tcgcatcctc cggcatggcg atggaggtca accggccctc gggatagatg
     1141 gcggccgcca actccaccgc ccgctgcgga ctgatcggat gcgctccatc ctcaacagcc
     1201 gacggagcag attgcgcagg gccgcgggtg gccggcgaca gaacctgcgt gatccagatg
     1261 atcggctcgg cccagttcat ataggctccc gacaggagca cggcgccgat cgccagacag
     1321 agatacagcg acaccgtttt gtgcagatcg aacagcaacc ggaacagggc gaacggccgt
     1381 cggatgacaa acgcgtgtcg ccattggccg ttcaccggcc accagacgat cacacctgtg
     1441 accaaggaca ggatcagcaa ccaggccgcg attgccgcca gggtcacgcc cgtcataccc
     1501 acgaacagtt ggtaatgcag tgcgaagatc gcatccatca aatacttggg cacccactcg
     1561 tcaggcccat aactgcgtac ccccgtcacc cgggcccggt agggatcgac aaaaatccgt
     1621 tgccaggctt tcgacggctc ctccatatag acagccatga cccgctcggg tttcgtcgcc
     1681 ccatagacct gcgtgatacg gctccccggc gccgccgcct gctccgccgc cgctagaatc
     1741 tcacctatcg gccggtagct attctgcccg tctgcagtcg cgtccaccgt cagcaacgca
     1801 ggattcagcc actcgtcgat ttcctggaag aacaccagga tactgcccgt caatccgaag
     1861 accaccagca gcgcccctgt ggtcagtccc aaatagagat gcgcctgcac ccaccacgtt
     1921 cgccacactc gcgcgcgacg gtcccgtact ccggcttggg cggcttgacg agcggcaact
     1981 ggaatcgact cagacggcat ggctctccca gacatgcgat tcacattcct ccgccgacgg
     2041 tctatcgagg cagcgtggcg gtagtggcga cacctccggc atgggtgccc ttgtttcacc
     2101 gacgaggcga cgacgcgcag gacggacgaa cactcattca tgacgcgggt gacgatcagc
     2161 tcgtcaccac gcgggaattg tccttattca gtgcggataa aaccgatgat caggaaagag
     2221 gaaccggagg accacggcca tgggccgcga tttgaaacag ggtgcgatac gacagcagca
     2281 acagaacgag tggaacaaat tcagaaacca cgagcgggag tcgtggaatc tcggggagga
     2341 tgaacgccgt ttcgtcctgg gtcaccgtgc aggcccaggt cgtcagcgga ctggcttccg
     2401 cctggccgtg gtggcaggga tcacgatccc ccccggcatg gagatgaaaa ctccgggagg
     2461 tcggcttttc gaaatcgatg aagcaggtat ggcagacaaa cccggccgcc acacgaatgg
     2521 ccaccagcag acaggcgacg aaaaagagca gcgacggggc ccgccccgtt cgcccacgga
     2581 gagacatgat gtggaggagc tcgttcacca caaacactct atacagtttc agacgcacta
     2641 ccatacgaaa ctgccaccct catgtccact acctgttgct cacaggtgct acagtccaca
     2701 ccggggtttc gtggtgcaga ccgcatcccc ccggcggctc gcgacatgtc gtcgtgaacc
     2761 actcttgttt ccgctcccgt caaacttcac gtttcacgcc cctagaactc catgcggatc
     2821 gaccccatga agaaacgcgg cataccgtag taggtcggac catacgagaa gacctgaccg
     2881 atatagcttt tgtcgagcag gttatcgacg ttcagctgtg ccgtgtaccg ggccgtgccg
     2941 acacgccagt gataactcgc catcaggttg gtgatcacat atcccggcgc ctgggccgtt
     3001 tcgccgaacc caatctggcg ctcacccacc ccctgtacgc cgactcccac tcgcaatcct
     3061 tggagcgttt cctcctggaa ctgatagacg gtccatagac tgccgctatt gacgggcgcg
     3121 ttgttgaggc gcttgcccat cgtcccaagc gcgggatcat cctttgtggt tttggcaaag
     3181 ggcgtgtagg cataggcccc gatgacgctc cagcccggca gaatttcccc gctgacgtca
     3241 aactctacac cacggctctc tccctcgccg accgccctgg tttccccggg aaaaaagacc
     3301 ggcaaattct gcttggtcag gtcgaagtag gccaatgagc cgataaatcg accgccgaac
     3361 agttccgtct tggcccccac ctcccattgt tgagccgttt gcggcggcag cggcacaacc
     3421 gaaccggcgg taaacgtatt cgaagcccca aagttttcct tataactgcc gtagagcgag
     3481 aactccggta ccggacgcca tacgacgccg gctcgtggcg aaatccgctc attcgtatcc
     3541 ttgatggtcg gcgtgcgaac gcccagattc tcgttggagg tggacgtctt cgcgttgtcg
     3601 taccggaatc ccgcgagaat atggatatgg tagggcagct cgatttgatc ctgcgcgtag
     3661 agaccgaacc agggcagcga ccacgtgtat ttcgtcacgt caccaggcgc gatgaccggc
     3721 ggtcccgccg tgtgaaccgg gttgaagata ttgatcacgt cgtcggtagc cggcgtaaac
     3781 cctgccatcg tcgcgcgaat gtcgttgtgg agatagtctc ccccgaacag aagcgtgtgc
     3841 ttgatccggc cggtggtgac gtggccggtg agctcgaggg cattgaacac attgcgcgtg
     3901 tagtcccgac cgtctgtatt ctgcgcaaag aagaatcgac tcacatcccc gttcgccgcg
     3961 gcattcccca cattctgtcc ggttaacgtc aattgatggt tgctgaaatt gaaccgatgc
     4021 ctgatcgacc aggcgtcgtt gaaggcatgc tccgtgatca atgagaccag atgatattta
     4081 tcgttctgca ggttccagcg ttcgccgaga ttcaactccc gcgcaatggg ggccggacgg
     4141 ttgcccagca gaggaatatt acctttgccc gtgagcgaga tatcgctgta ctcatacttc
     4201 agagtagagg tggtgtgatc cgtgattcgc catcgcacct gcggggacac aatcagccgt
     4261 tcattgcccc cgaactgctg aaacgtctgg ttcgtttgat agccgatatt caatcggtag
     4321 gatacggagt tgtttgcggt caacggaccg gtcagatcgg cgttggtccg gtaccagcca
     4381 tacgagccga cctgctgctg cagcgaataa tagggctgat ccagcggttg cttggtgacg
     4441 aaattaatga tcccgcccgg ctcagcccgc ccgtagagaa tggagcccgg gcctttcaag
     4501 acctccaccc gctcgatatt cgtcagatct tccccgtgaa accactgact ttggaaggga
     4561 tacccgtcac ggtagaagtt aaactggtcg aagccgcgca tattgaactg catgtcgccc
     4621 tcagcgccgc tgatgacacc gctgatgttc ttcaaggctt gatcgacccg caccacctgc
     4681 tgatctcgca tcacctgctg aggcacaacc ttcaccgaca ccggtgtatc catgatcggg
     4741 gtgtcggtct tggtcgccgt cacggtgttc gtcacgtgat aggactcggc ttgagccaca
     4801 atatgcaccg gcttgacatc aacaacggga gcatcgtccc ttgtggatgc gcctgttccg
     4861 gccaagtctt cagccggaac cgggacggga agcggcacgg gcagagccgg cggagactgc
     4921 cttgcctgcg ccgccttgtc tcctccggat tccccggtcg attctccctg agccggtgcg
     4981 gcaactggcg tggcagaagt cttgtccgtc gccaccggtt tgtgcggacc gatacaggcc
     5041 gtcagcaacg taaggccggc taccgcgacg attctgccga tgcccgcgga accgcggcga
     5101 agaggtatga aagatcgaga tgcgttctga cacgagtccg ttgacttcat cgacaacact
     5161 cctccttcgg ttcccgctct acacgcacgg aaccggaact cgccgggggc agaccggtga
     5221 cgaaggctga gcggctgcac gcagggtgta cggggctggt ccatcaaaga cctgcccctt
     5281 ccggcatcgg atgatgccgg ttccctggcg tgcggcccgc cttcggtgca gcggccgtgc
     5341 gactcccaac taggtgatat ggatgagaac cctgcgttag gagacgagga ggtgacgggg
     5401 tggcccgcgg ccgtgaggaa caatcgcaga acgactcccg aacgagactc tgaaaagcag
     5461 gaacagaaga aacagcgccg ccaccagtgg cagaagcggc acctccggca ggatataggc
     5521 cgactcgtcc tgattgacgg aacaggccca gtcactcagc ggactggtcg gcgccttgcc
     5581 gtgatggcag ggcaccctgt ctcctccggc atgaaggtga aacgaccgcg ctgacggccg
     5641 ttccatctcg ttgaagcaac tgacgtgaag aaatccggcg acgagacgaa tgccgatcag
     5701 gaacaaggcc aacagcaccg catggcgctg gccgcggcct cgagatcccg acagaggcat
     5761 gaatggacgg gcaggtttca cagaacattc cggtagaacg taaggggcct caccctacgg
     5821 aaccgcacgc agaattgtct accgatgcct gctcacgctt gctacacagc tctctgaaac
     5881 actcggacag gcccggcatt gtgaccaagg ccgggcctat atcaagaacg attcggaact
     5941 ggatcagtaa taaatcgaat acccaatcga ggccgtcgtt ccacgtcccg caaaatagaa
     6001 gctgttggtg aaggaaatct ggttgaacgg cgttgcgtac tgtttgttca gcagattctc
     6061 taccccgaac cggagcgtgc ccggccctgc tttgacggtg ctgatcagat cgaccaggaa
     6121 gtattccgtc tgaccgaagg gatccgcggt gggatcgatg ccggaattga acgccgtcag
     6181 cgagcgcgag cggctgccgg aatacagcac ttgaacccgg ttgcgccagt cccactccgg
     6241 caccgtcagg tgttcgaggt aggcggtgat cttctgcggg gcaatggaga agccgttcaa
     6301 cggcacgcgc acatcaggat tgaacccgac tttctgatcg ccttccacaa aggtgtaggt
     6361 gccgcccagg cgcacccgtt cgatcggctg aagatcaagt gtggcttcca caccgtagat
     6421 ggtttgcggc gcacgccgga gtgaattcgt aaactggtca aaattcagac ccagcgaaga
     6481 cttggaaatg tatccggaca ccgaagcctg aactttgctc catttgccac gcaacccgag
     6541 ttcataatta ttcacgcgct gcggctgcaa ccgctggagc gaaatggcgg tccccggcgg
     6601 cacattgccc aacgcattgt cgatcgatcc gaccggcacg ttgaacccct ggctgaaatt
     6661 gaagaacagg tccaacgggt ccagcaggtg gtagacaaat ccggcattga agaccgtcgt
     6721 atcaaactcg atcgcactcg ccgcgaggaa ggacccgttg ccggtaaagt cgctgctcgt
     6781 cactttgaca cgctcatacc gaaccccgcc gcgcaagacc aacgcggcca gcggagtcca
     6841 ctcgccctgc gcgaacaccg cggtgctgtt gaagacccgc gagggcgacg aggccacctc
     6901 gccggacttg ctgaacacgc gtccgccgga tccatcgaag accgactgat cgtagagcgt
     6961 cgacgactgg gcgccatgtt ggctggagaa gtccatgccc cacacaattt ccggcttccc
     7021 atagatcggg atgggcgtag tgatgtcgag cctggttccc aacacgtcgc tttggttata
     7081 gccttgcagc acatccgtgc ccccgaacag ccggctgtcc aaagttggaa accgcgtctg
     7141 ctgtgtgcgg tagtagccct gcaaatgcac ccggctgtcg agaaacagat gaggatgggt
     7201 gtagtcggcg ctgacctgcg tgttcgttag cttgggttgg tcggccaacg acaagcctgg
     7261 gacgtaccgc gcaaacgtcc gtggcaaggc gtccacattg ggatccacca ggtagttcgt
     7321 atcctgccag gactgcttgc ggttgaaggt cagttggaac cggtggtcgc cgaaggtcgc
     7381 cccgaacttg ctcatgatgt tgtagttctt ggtgtcggca aatccaccga ccgtattggt
     7441 gccgggcatg gt
//
LOCUS       DAOQPD010000117         7322 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_5699_length_7322_cov_24.473923, whole genome shotgun sequence.
ACCESSION   DAOQPD010000117 DAOQPD010000000
VERSION     DAOQPD010000117.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 7322)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7322)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7322
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5699_length_7322_cov_24.473923"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..353)
                     /locus_tag="PK063_17520"
     CDS             complement(<1..353)
                     /locus_tag="PK063_17520"
                     /inference="COORDINATES: protein motif:HMM:NF012655.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HMZ98905.1"
                     /translation="MKATNASSRNASHDRQASLISSAANLFAAKGFKGTTTKEIAKAA
                     GVSEALVFKYFPTKRALYTAILAEKAPLSELLSAVEEFARKRDDHRVFTLIASYRIRP
                     GADPTMLRLLLFSAL"
     gene            complement(491..1033)
                     /locus_tag="PK063_17525"
     CDS             complement(491..1033)
                     /locus_tag="PK063_17525"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98906.1"
                     /translation="MMLRGQTVLHSRRCLLVFTLGAVLLFPITPALAVPMENDPNGFE
                     GIPWGAAFTESDQFVKVEEAGRIQTYELTSTPRKLGPATVESMKFSTVEGKFARVMVR
                     YTGKDTHDRLLTFLQQQFGPIDHTPGQMAGGAVKFFNWQGPDSAIILRYDLRTSQGVI
                     FFESEAFRVKLNEGNLPPVP"
     gene            complement(1033..1584)
                     /locus_tag="PK063_17530"
     CDS             complement(1033..1584)
                     /locus_tag="PK063_17530"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98907.1"
                     /translation="MKAMHDAFSRWSPLRLLQRIGCVSALLLLTAGPVLAITMANDPH
                     GYHDLSWGIPLTDVPDLMVTRENTHTIDYEFRDRQPVYADIPVESVHLSTVDAQFARV
                     TIRYRGAQAHKQVLQYLERTYGVIERLPGQMMRGLNQQYTWRGTETEITLTYEANRDR
                     GFVFIESRNLAPRFQDLMSDTAE"
     gene            1720..2217
                     /locus_tag="PK063_17535"
     CDS             1720..2217
                     /locus_tag="PK063_17535"
                     /inference="COORDINATES: protein motif:HMM:NF014795.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-binding protein"
                     /protein_id="HMZ98908.1"
                     /translation="MVDSDVFVQALENLGVNFFTGVPDSLLGGIIEELLTRKLYTSAV
                     REDEAVAMAAGAFMAGKIPAVLMQNSGLGTSLNTLLSLNMIYRQPCILLVSWRGFEGK
                     DAPEHLVMGETMPQLLDTMKIPHRTLSEPTMAEDLRWVAQTFMKQRIPVALLIKKGII
                     KGLHP"
     gene            2214..2792
                     /locus_tag="PK063_17540"
     CDS             2214..2792
                     /locus_tag="PK063_17540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HMZ98909.1"
                     /translation="MRPEQGTMQSRAQAMAALLELLTDQPVIICNGFPSREAQKLADR
                     PTHFYMIGSMGNAAAIGVGVALSKPSKKVIVFDGDGNVLMGMGTLATVGALRPKNFIH
                     VVFDNEVYGSTGNQPTISNVVQLEKVAKAAGYVAVERVLDREDLVYEFKDMLKNDGPS
                     MLLVKVNEFVEDAGRIALEPPAITARFMKAIE"
     gene            2862..3956
                     /locus_tag="PK063_17545"
     CDS             2862..3956
                     /locus_tag="PK063_17545"
                     /inference="COORDINATES: protein motif:HMM:NF012488.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HMZ98910.1"
                     /translation="MILLNPGPVNVSERVRQALLRPDICHRESEFSDMLQRIQQKLLT
                     AFVPGAESEYVAVILTGSGTAAVESAVMSCLPLGKRMLVLNNGVYGERLSNMIGLQRL
                     GVSELKSEWHVRPDPERLRLALRQHPEVHAVSMVHHETTTGLINPVKEIAEVVDSLNR
                     VFVLDSVSGLAGEPIDIAGSHIYMVAGTAGKCIQGFPGVSFVLLRKGFLDQMRKYPKR
                     SWYLTLTHYVDEQGRGIVPFTPAVQVYYAFEEALDELLEEGVTSRFHRYRRMATRIRE
                     RMAGMGVQPFLPADVQSNTITAFHLPAGLSYTTLHDQLKARGYVIYAGQGQLESKVFR
                     VANMGALTESQINGFLGAFEEVLAGAAARA"
     gene            3953..4672
                     /locus_tag="PK063_17550"
     CDS             3953..4672
                     /locus_tag="PK063_17550"
                     /inference="COORDINATES: protein motif:HMM:NF024214.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="HMZ98911.1"
                     /translation="MKAIILAAGVGKRLWPVTQHKPKCLIEIGGQTLLSRYLESLASV
                     KIRQATIVVGYKQEMIRAAVGSQCHGVDISYLVNEEFHRGSISSLWIARQALTDDVVI
                     MDADVLFHREILRRLVASPYENCLLMDDTVKQTGEECMVVVQGDRVIALSKKVPDRYD
                     LAGEGVGFLRVRRADTAHVIASLKGYIDQDRWDMEYEDGLLQYFRDVKVGHEKIGGLP
                     WTEIDFPEDVTKAEREILPRL"
     gene            4725..6179
                     /locus_tag="PK063_17555"
     CDS             4725..6179
                     /locus_tag="PK063_17555"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: protein motif:HMM:NF013250.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HMZ98912.1"
                     /translation="MSESTLQRGAELQGLSTAILLPGAGLFGDRPGRGLADVGPLTHI
                     GGLSLFQRTVLTLQRGGIRQLIVLAGPDEELLKQALARGARVTIPVRWMPVREFPLDD
                     PRTWESLAAEVRGFCLVAGVQAVFSKGLIEHLRQTVRDGEALVVTREAGSIEPAAGRR
                     NPVVAFQEGRLVSFHNQPVQQGHQVAADLVVLPASILNPPSGAAAPLTSGLAEAPGMT
                     PMRRWLERAAIEGRVRVVAAASHAGLWYREVWDQASAGHAERTLFRSLKGEAEGFVDR
                     YFNRTFSRLLTRLFLQLKCSPNTITMVATAVGLLSAVGFGLGTYTAGIVAALLFQLAA
                     IIDCCDGEVARLTFTESPFGAWLDIAMDNVVHIAIFAGIACGAYLRHADAPEAWVSLA
                     LGSAAVFGNAMAFWLVTKAQKIGATRGWNTPKQAAWSDFILKNVASRDFSVVVFLFAV
                     ADKLDWFLWMAALGSTVFWLMMVWVIRPSARARA"
     gene            6172..7167
                     /locus_tag="PK063_17560"
     CDS             6172..7167
                     /locus_tag="PK063_17560"
                     /inference="COORDINATES: protein motif:HMM:TIGR00374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysylphosphatidylglycerol synthase transmembrane
                     domain-containing protein"
                     /protein_id="HMZ98913.1"
                     /translation="MLKAALLLLGALTLSALVWHIGIGRIYDAVTQLGPAAMVLVLLP
                     SLLMYVLEAYGWRVTLGAWAKGVPFWRILAIRTAGEVVNMTTPTAYVGGEPLKAYLLN
                     RHGVPLVEGLASVVTAKTTMTIAQILFILAGIGLGFWLLGSGGSAGQTITAGLVSVGL
                     LLFGVGAFVIVQRQGMFGWILALLRRIGLRIQFLEAREQQLLELDRTIAGFYSHQRQA
                     FLLSTGLFLLGWLAEALEVYVMVLCMGQSINVLPAVAIGALSVFIKGGTFFIPGSLGA
                     QDAGNLFLLSAFGYGEVTGITFALLRRFREFVWIALGLGCLAMMTKGADPSPSQK"
BASE COUNT         1376 a         2014 c         2333 g         1599 t
ORIGIN      
        1 tccagcgcac tgaagagcaa caggcgcaac atcgtgggat cggctcccgg gcggatgcga
       61 tagctggcga tcaacgtaaa gacccgatgg tcgtcacgtt tgcgcgcaaa ttcctccacg
      121 gcgctcagca gttcgcttaa gggagccttt tcggccagga tggcggtgta gagggctcgt
      181 ttggtcggaa agtacttaaa gaccagggct tcgctcacgc cggcggcctt ggcgatttcc
      241 ttggtggtgg tgcctttaaa ccctttggcg gcaaacaggt tcgcggcgga ggaaatcagg
      301 ctggcctggc gatcgtggct ggcattgcgg gagctggcgt tcgtcgcttt cacgtcgtcg
      361 ttcgtccggt gagtgagtgg ttactcaccc ctcaaggtat catgcaagaa cgaagtgtga
      421 caaggatcga gaatattccg tccaccgcgc ggagagcccc gatggaggag aggaatgggt
      481 agaggatcga ttagggaacg ggaggcaaat tcccttcgtt cagcttcacg cggaacgctt
      541 cgctctcgaa aaaaatcact ccctggctcg tgcgaaggtc gtagcgaagg atgatcgcgc
      601 tgtcggggcc ctgccagttg aaaaacttca ctgcgccgcc ggccatctgg ccgggagtgt
      661 gatcgatcgg gccgaattgt tgctgcagga acgtcagcag ccggtcgtgg gtgtccttgc
      721 cggtataccg gaccatgacg cgggcgaact tgccttcgac cgtgctgaac ttcatcgact
      781 cgactgtcgc cgggcctagc ttcctcggcg tggaggtcag ttcatacgtc tggatgcggc
      841 cggcctcctc caccttcacg aactggtccg attcggtaaa ggcggctccc cagggaatgc
      901 cttcgaaacc gttcggatcg ttctccatgg gaacagccag cgccggggtg atggggaaca
      961 gcagcaccgc gccaagcgtg aaaaccaaca ggcagcggcg tgagtgaagg acggtctgtc
     1021 cgcgcagcat cattattccg ccgtatccga catgagatct tgaaagcgtg gcgccagatt
     1081 gcggctttcg ataaagacaa acccgcgatc ccggttggcc tcataggtca gggtgatctc
     1141 tgtttccgtt cctcgccagg tatattgctg gttgagtcct cgcatcatct gtccgggaag
     1201 ccgctctatc actccatagg tccgttcgag atattgcagc acctgtttgt gcgcctgcgc
     1261 gccgcgatac cggatggtga cgcgcgcaaa ctgcgcatcg accgtcgaga ggtgcacgct
     1321 ttcgaccggg atgtcggcat agaccggctg gcggtcgcga aattcatagt cgatggtatg
     1381 ggtgttctcg cgggtcacca tgaggtcagg cacgtcagtg agaggaatgc cccacgacag
     1441 atcgtggtag ccgtgtggat cgttggccat cgtgatggcc aacaccggcc ccgccgtgag
     1501 gagtagcagg gcgctgacgc acccgatgcg ctgcaggagg cgaagaggcg accatcttga
     1561 aaacgcgtcg tgcatggctt tcacaaggtc ccacctggca cgctaccatg gccgttcaca
     1621 tggcggcaac tctcggtgcg gcgttcttgt gaatgaggga ccccttggat ataatgcgcc
     1681 tcttgtgccg gggccaatcg ggcgacagga gcatggttca tggtcgacag tgacgtattt
     1741 gtgcaggccc tcgaaaatct gggcgtcaat ttcttcaccg gagtgccgga ttccctgctg
     1801 ggcggcatca tcgaggaatt gctcacgcgc aagctctata cgtctgctgt gcgtgaggac
     1861 gaagcagtcg ccatggcggc cggcgccttc atggccggga aaatccctgc cgtcctcatg
     1921 cagaactccg gactgggcac ctcgctgaac accctgctct cgctcaatat gatctatcgg
     1981 cagccgtgca tcctgttggt atcctggcgc ggctttgaag ggaaagacgc gccggaacat
     2041 ctggtgatgg gcgagacgat gccgcagttg ctcgacacga tgaaaattcc tcatcggacc
     2101 ctatcggaac cgaccatggc ggaggatctt cgctgggtgg ctcagacctt tatgaagcag
     2161 cggattccag tggccctcct gatcaagaag ggcatcatca aggggttgca cccatgaggc
     2221 cggaacaggg aacgatgcag agccgggcgc aggcgatggc cgcgctgctg gaactgctga
     2281 cggatcagcc cgtcatcatc tgcaacggat ttccttcgag ggaagcccag aagcttgccg
     2341 atcggccgac gcatttctat atgatcggct cgatgggcaa tgccgccgcc atcggcgtgg
     2401 gcgtggcgct ctccaaaccg tccaagaaag tgatcgtgtt cgatggagat ggcaacgtat
     2461 tgatggggat gggtaccctt gccaccgtgg gcgcattgcg gccgaagaat tttatccatg
     2521 tcgtcttcga caatgaagtg tatggctcga caggaaatca gccgaccatc tccaatgtgg
     2581 tccaattgga aaaagtggcg aaggcggccg ggtatgtggc ggttgaacgg gtcttggacc
     2641 gtgaagatct cgtgtacgaa ttcaaagata tgttgaagaa cgacgggccc agcatgttgc
     2701 tcgtcaaggt gaacgagttt gtcgaagatg ccggacggat tgcattggag ccgccggcca
     2761 tcaccgcgcg tttcatgaaa gccattgagt aattgcggcg cactgaacgt gctgagtgag
     2821 cccgtcctgc tccgttccga tcaacagcct gaggcacaac catgatactt ctcaatccag
     2881 gtccggtaaa tgtgagcgaa cgggtgcggc aggcgctgct gcgtccggac atctgccatc
     2941 gggagtccga attttccgac atgctgcagc gcattcagca gaagctgctc accgccttcg
     3001 tgcccggtgc ggagtccgag tacgtggctg tcattttaac ggggtccggc acggcggccg
     3061 tcgagtcagc agtgatgtcc tgccttccgt tgggcaagcg catgttggtg ctcaacaatg
     3121 gggtctatgg cgaacgactg tccaatatga tcgggttgca gcgactcgga gtgtccgaac
     3181 tcaaatcgga atggcacgtc aggcctgatc cggaacgact ccggttggcc cttcgccagc
     3241 atcccgaagt gcatgcggta tcgatggtcc atcatgagac gacgaccggt ttgatcaacc
     3301 cggtgaaaga aattgcggag gtcgtcgaca gtctcaaccg ggtgttcgtc ctcgattccg
     3361 tcagtggcct cgcgggcgaa ccgatcgata tcgccgggtc gcacatctat atggtggcgg
     3421 gaacggcggg caagtgcatt cagggattcc ccggcgtgtc gtttgtcttg ctgcgcaagg
     3481 ggttcctgga tcagatgcgg aaatatccga agcggtcctg gtatctgacg ctgacccatt
     3541 atgttgatga acagggccga gggattgtgc cgttcacgcc ggcggtgcag gtgtactacg
     3601 cgttcgagga ggcgttggac gaattgctgg aggagggggt gaccagccgc ttccatcgat
     3661 atcgtcgcat ggcgacgagg attcgcgagc ggatggcggg catgggggtt cagccgttcc
     3721 tgccggccga cgtgcagtcg aatacgatta cggccttcca tcttcctgcg ggtctgagct
     3781 acacgaccct gcatgatcag ctcaaggccc gcggctatgt gatctacgcc ggtcaagggc
     3841 aactcgagtc gaaggtgttc cgtgtcgcta atatgggcgc tctgaccgaa tctcagatca
     3901 atggattcct gggtgcgttc gaggaagttc tcgcaggagc ggcggcgcgc gcatgaaggc
     3961 catcatcctc gcggcaggag tcgggaaacg cctctggccg gtgacccagc ataagccgaa
     4021 atgcctgatc gagatcggcg ggcaaaccct gttgtcccgc tatctggaat ccctggcgtc
     4081 ggtgaagatc aggcaggcca ccattgtcgt cggctacaaa caggagatga tcagggcggc
     4141 ggtaggttca cagtgccatg gcgtcgatat ctcctacctc gtcaacgagg agttccatcg
     4201 cggcagcatt tcctcgttat ggattgccag gcaggcgctg accgatgatg tggtcatcat
     4261 ggacgcggat gtgttgtttc atcgggagat ccttcggcgt cttgtggcgt ccccctatga
     4321 aaactgttta ctcatggacg atacggtgaa gcaaacgggc gaggaatgta tggtggtggt
     4381 gcagggtgac cgcgtcatcg ccttgagcaa gaaggtgcct gatcggtatg atctcgccgg
     4441 cgaaggtgtc gggttcctcc gggtgcgccg ggcggataca gcgcatgtga tcgcttccct
     4501 caaggggtac atcgatcaag accggtggga catggaatac gaggacggat tgttgcagta
     4561 ttttcgtgac gtgaaggtcg ggcatgaaaa aatcggggga ctgccctgga ccgagatcga
     4621 ttttcctgaa gatgtgacga aggcggagcg ggaaattctc ccgagactgt agcgcacagg
     4681 cacccgccag cggccatcca ccaataggaa ccccattcgg aatcatgagt gaaagtacct
     4741 tacaacgagg cgcggagctg cagggattga gcacggccat tttactgcct ggtgccggtc
     4801 tcttcggtga tcgtccgggg cgaggtcttg ccgacgtggg gcccttgact cacatcggag
     4861 ggttgagcct ctttcagcgg acggttctca ccttgcaacg gggcggcatc cgccaattga
     4921 tcgtgttggc cggtcccgat gaagagctgc tcaagcaagc gctggcacga ggcgcgcgcg
     4981 tgacgattcc ggtccggtgg atgccggtgc gtgaatttcc gctcgacgac ccgcgtacct
     5041 gggaatccct cgccgctgaa gtccgggggt tctgtctcgt ggccggagtt caggccgtgt
     5101 tttccaaggg cctcattgaa catttacggc agaccgtgcg cgacggcgag gcactggtgg
     5161 tcacgcgtga agcgggatcg atcgaacctg cggccggtcg caggaatccg gtcgtcgcat
     5221 ttcaggaagg gcggctggtt tcatttcaca atcagcccgt gcaacagggg catcaggtcg
     5281 cggccgacct ggtcgtgttg cccgccagca ttttgaaccc gcccagcggg gcggctgccc
     5341 cgttgacgag cggcctcgcg gaagcgcccg gcatgacccc catgcgtcgc tggctggaac
     5401 gggccgccat cgaaggacgg gtgcgggttg tggctgccgc gtcccacgcc ggactctggt
     5461 atcgcgaagt gtgggatcag gccagtgccg gacacgctga gcgcacactg ttccgttcgc
     5521 tgaaaggcga agccgagggt tttgtcgatc ggtatttcaa ccggacattt tcgcggctct
     5581 taacgcgact ctttctccaa ttaaaatgct ccccgaacac catcacaatg gtggcgaccg
     5641 ctgtcgggct cctctccgct gtcggattcg ggttggggac ctatacggca gggatcgttg
     5701 cagcgctgtt gtttcagctg gctgcgatca tcgactgttg cgacggtgaa gtggcgcgcc
     5761 tcacttttac ggaatccccg ttcggtgcct ggctggatat cgccatggac aatgtggtgc
     5821 atatcgccat ctttgcaggg attgcctgcg gggcctacct tcggcacgcc gatgcgccgg
     5881 aggcgtgggt gtcattggcg ctcggaagtg cggccgtgtt cggtaatgcc atggcgttct
     5941 ggctggtcac gaaggcccaa aagatcggtg ctacgcgagg ctggaatacc ccgaagcagg
     6001 ctgcctggtc ggacttcatt ctcaaaaatg tggcgagccg cgacttctct gtggtcgtct
     6061 tcctgtttgc cgtcgcggat aaactggact ggtttctctg gatggctgca ctcgggtcga
     6121 ccgttttctg gttgatgatg gtgtgggtga tccgaccctc ggcacgggcc cgtgcttaaa
     6181 gcggccctcc ttctcctcgg ggcgctgaca ctctcggcac tggtttggca tatcggcatc
     6241 gggcgtattt acgatgcggt gacgcaactc ggtcccgccg ccatggtgct ggtccttctt
     6301 ccctctctcc tcatgtatgt gctcgaagcc tatggttggc gcgtgacgct cggcgcctgg
     6361 gcgaagggtg tgccgttttg gcgcatctta gcgattcgta ccgccggcga agtcgtgaac
     6421 atgaccacgc ctacggccta tgtggggggc gaaccgctga aggcctatct tctgaatcgc
     6481 cacggcgtgc cactcgtaga gggcctcgcg tcggtcgtga cggcaaaaac gaccatgacc
     6541 atcgcccaga ttctgttcat tcttgcgggc atcggcctgg gattctggct attgggttcc
     6601 ggcggatcgg ccggacagac gatcaccgcg ggattggtca gcgtgggcct gctgctcttc
     6661 ggtgttggcg cctttgtcat cgtgcagcgt cagggtatgt tcgggtggat cctggcgctg
     6721 ttgcgacgca tcggtctgcg catccagttt ttagaggcgc gtgagcagca attgctcgaa
     6781 ctggatcgca ccatcgccgg cttttattcc caccaacgac aggcctttct cctttcgacc
     6841 ggactgtttc tgctcggttg gctcgcggag gcgctggaag tctacgtcat ggtgctgtgc
     6901 atggggcaat cgattaacgt gttgccggct gtcgccattg gtgccttatc cgtcttcatt
     6961 aaaggaggga cgttttttat tccaggcagt ttgggggcac aggatgcggg caatctgttc
     7021 ctcctctccg cgttcgggta cggcgaagtc acaggtatta cgtttgcgct tctgcggcgc
     7081 tttcgggaat tcgtgtggat tgccttaggg ctgggctgcc tggcgatgat gacgaaaggt
     7141 gccgatcctt ccccttcaca aaaataatcc tccgttccac accgggactt gtgccaggct
     7201 gagacagacc agccatgccg aatttcctac agcgcaattt cagtggaaga tgtggccgaa
     7261 ttggacctcc tcggctacac tagggagcaa ccctgagata tccaatccca ggtaacggtt
     7321 tt
//
LOCUS       DAOQPD010000118         7307 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_5719_length_7307_cov_25.357970, whole genome shotgun sequence.
ACCESSION   DAOQPD010000118 DAOQPD010000000
VERSION     DAOQPD010000118.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 7307)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7307)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7307
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5719_length_7307_cov_25.357970"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1753
                     /locus_tag="PK063_17565"
     CDS             <1..1753
                     /locus_tag="PK063_17565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="RiPP maturation radical SAM C-methyltransferase"
                     /protein_id="HMZ98914.1"
                     /translation="VDCHHLNVRFAHKIGVPLYESICEKRALFGEWLFSYLLFRDNPK
                     RAAYPRVFKPVFEQIARESGQPVSFFEDMGSRTAPQFLTAAMAGIYWGQYKLVGFTST
                     FDQNVASLTMAKLIKDLYPDVKIVFGGANFDGEMGLEYFRAFPFIDYVVVGEGEVTFP
                     ALVDYVLRGSTGPCPKGVIYREDGEVKLEPNTALFTEFAQTGPPDYDDYYHLLAELGT
                     EASRGLDRILLYEGSRGCWWGEKHHCTFCGLNAQSMKFRAKSAEQVAQEMAYLSSRYD
                     TTRFRLVDNIIDMKYVDNLFGRFAAAHCDLDVFIETKSNLQKSQIRTLAVGGVKCMQP
                     GLESLSLSQLKAMDKGVTPMQNIICLKWSCYYRVAVSWNILLGFPGETNEDYRRQIDL
                     LPSLFHLQAPEATGKFWLQRFSPYFTRPHEYGVRITGPGTAYEYVYDAARVDLRKIAY
                     DFEYELDDWPVDPQVYQELTGLIEEWQRRARSNDRPFLYYSKAMEYVTIYDGRDPDMP
                     TRQRYDWPAAGIIEACNEAAKSRDQIRAALGEAKRDSIYSEDDLTEALSLLTSRRILY
                     EEREKYFTLAIPEHPYY"
     gene            complement(1930..2262)
                     /locus_tag="PK063_17570"
     CDS             complement(1930..2262)
                     /locus_tag="PK063_17570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenosugar biosynthesis-associated
                     peroxidase-like protein"
                     /protein_id="HMZ98915.1"
                     /translation="MDCYYHSKDLGKFGDMGKGNPVLWEKFMSYYSAVFAEGALTERE
                     KALIALGVAQAVQCPYCIDAYTQACLEKGSNIEEMTEAVHVACAIRGGASLVHGVQMR
                     NVAEKLSM"
     gene            complement(2349..2618)
                     /locus_tag="PK063_17575"
     CDS             complement(2349..2618)
                     /locus_tag="PK063_17575"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98916.1"
                     /translation="MASQVPPQKPAAPSANAQDVWDVELLHVHVSRKGQLVNAEWALH
                     PQIKADLSAEEWRELGELMNKVTTIVGHRFSQALNEAEPTPPGNA"
     gene            complement(2746..3567)
                     /locus_tag="PK063_17580"
     CDS             complement(2746..3567)
                     /locus_tag="PK063_17580"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008934 - inositol monophosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006020 - inositol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046855 - inositol phosphate
                     dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HMZ98917.1"
                     /translation="MHTSHALPSEELDRYLATAVQAAEAAGHVLLEHAKTGFRIDHKA
                     AINLVTDADRQAEECIVRSILSSHPTHRILAEERGRDGATESPYQWIIDPLDGTTNFA
                     HGFPFYSVSIGLEYHGDCIVGVVLDPTRQELFTGVAGKGAYLNGERLRVSNNETLGRS
                     LLVTGFAYDIRETTNNNLDHFSRISLRAQGVRRTGSAALDLSYVASGRFDGYWEVKLS
                     PWDMAAGIVIVREAGGLVSGFQKDTFSLYGQELVATNGLIHQQLLDVIHQRPATS"
     gene            3816..4328
                     /locus_tag="PK063_17585"
     CDS             3816..4328
                     /locus_tag="PK063_17585"
                     /inference="COORDINATES: protein motif:HMM:NF016924.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HMZ98918.1"
                     /translation="MEELTDILVGLEQRISAYRNRYQELEKKRRRLDDEIAMIKKYLE
                     LAETLYRVEADKAKLASLSSQIITDEKGIRPLPVTDVTDQSREILLGKSKYVGKSVPE
                     AAYQILREASRPMHAKELLQRLLEGGLQIKGKTPLTSVATSLKRDKRFQKVGPNTFAV
                     TTQQELTAVV"
     gene            complement(4576..>5530)
                     /gene="lpxC"
                     /locus_tag="PK063_17590"
     CDS             complement(4576..>5530)
                     /gene="lpxC"
                     /locus_tag="PK063_17590"
                     /EC_number="3.5.1.108"
                     /inference="COORDINATES: protein motif:HMM:TIGR00325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008759 - UDP-3-O-[3-hydroxymyristoyl]
                     N-acetylglucosamine deacetylase activity [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="UDP-3-O-acyl-N-acetylglucosamine deacetylase"
                     /protein_id="HMZ98919.1"
                     /translation="SAGFYEGGTVRFQQTIGSPVSCSGVGLHSGQPVTLTLRPAPPNT
                     GIVFIYRHDPEETLIPASISNKVPTELCTAISVNGHQVKTIEHLLAALVGMEVDNVYA
                     EVNAGEVPVLDGSSSPFVRLIRAAGVIPQTRRQSYVKIMQPIEVVDGSKRVRIEPSST
                     PKITYSIHYDHPLIQTQTYTYTCSAQAFEQDIAQARTFGFLHEVEALWSRGLGKGGTL
                     DNTIVLSKEGVVNESGLRFSNEFVRHKVLDLIGDIALLGFPFIGHVVAERSGHAMHTK
                     LVEQILLQRDKWALITGEHAVAASESRPSLGLLRPAPSLAI"
     assembly_gap    5531..5630
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<5631..6298)
                     /locus_tag="PK063_17595"
     CDS             complement(<5631..6298)
                     /locus_tag="PK063_17595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HMZ98920.1"
                     /translation="MEKIKVLIADDHRVVREGLAAILKTKEDINVVGEAQDGVEAVEK
                     TKTLMPDVILMDVSMPRMGGIEATRQIKREFPHMGIVALTMYEEQQYIFDLVRAGATG
                     YLLKDSESSQIVAAIRAIYRGESLIHPSVASKILAEFSLMSQKKGKKPAWVEHDLTER
                     EITVLRLVADGKTNKEIANSLDLSEKTVKNHVRNIFHKLQVYDRTQAAILAIRKGLIE
                     LEPRP"
     gene            complement(6285..>7307)
                     /locus_tag="PK063_17600"
     CDS             complement(6285..>7307)
                     /locus_tag="PK063_17600"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HMZ98921.1"
                     /translation="RGGTALMEIFANDPLVRIVGVADISPEAPGLGLAKRLHIRVTRN
                     YRQLLKMGPVDLVIDVSGNPEVGEYLQDIRRMGVSVIGGASAKFMWQLIEARIRATAD
                     IEKALNKYQSLYRLYVKETGAAVTEERTRIACEIHDGLVQSLAGVNFKLELSQELLRK
                     NPQASLATIRESKAQLKLAIQEARQVIFNLRPLHYDKMELIPALTNYLKSYETQYHIK
                     TAFSVTGDETILFPRTKIFLFRIVQEALSNVQKHAKAGRVSVQLDIRLDLLQVTISDN
                     GIGFDMDAVLRDPEKWDHFGIRGILERARLVGGEATIDSKKGRGTRIVLRIPLADKET
                     IRHGKN"
BASE COUNT         1558 a         1919 c         2085 g         1645 t
ORIGIN      
        1 ggtcgattgt catcatctca atgtgcggtt tgcccacaag atcggtgttc ctctctacga
       61 atcaatttgt gaaaagcggg ccttgttcgg cgaatggctg ttctcctacc tgctctttcg
      121 tgacaatccc aagcgggccg cgtatccgcg cgtgttcaag ccggtgttcg agcagattgc
      181 gcgagagagc ggtcagccgg tgtcgttctt tgaagacatg ggttctcgta cggccccgca
      241 gttcctcacc gctgcgatgg cggggattta ttggggtcag tacaagctcg tcggattcac
      301 gtccaccttt gatcaaaatg tcgccagcct cacgatggcc aagctcatca aggacttgta
      361 tcccgacgtg aaaatcgtgt tcggtggcgc gaatttcgat ggcgagatgg ggctggaata
      421 ttttcgagca tttccgttca tcgattatgt ggtggtcggc gaaggagagg tcacgttccc
      481 tgcattagtc gactatgtct tgcgtgggtc gaccggcccc tgcccgaaag gcgtcatcta
      541 ccgggaagac ggtgaggtga aacttgagcc gaatacggcc ctgttcacgg agtttgccca
      601 gaccggaccg ccggactatg acgactacta ccacctgctg gcggaactcg gcactgaagc
      661 ctcgcgcggc ctggatcgta ttcttctata tgaaggttcc cgaggctgct ggtggggcga
      721 gaaacaccat tgcacctttt gcgggctgaa tgcgcagagc atgaaattcc gggcgaaatc
      781 cgccgaacag gtcgcgcaag agatggcgta cctctcgagc cgctacgaca cgacccgctt
      841 ccggctggtg gataacatca tcgacatgaa atatgtcgac aacctgtttg gacgatttgc
      901 tgccgcgcat tgcgatctgg acgtgtttat cgagaccaag agcaatctgc agaagagcca
      961 gatccgcacc ctggccgtgg gtggcgtgaa gtgcatgcag cccggcctgg aaagcctgag
     1021 tctttcgcag ctgaaagcga tggacaaggg cgtcacgccc atgcagaaca tcatctgcct
     1081 caagtggagt tgttattatc gggtcgcggt gtcctggaat attctgctcg ggtttcccgg
     1141 cgaaacgaat gaggattatc gccggcagat tgatctcctg ccctccctat tccatttgca
     1201 agcgccggag gccaccggga aattctggct gcagcgcttc agcccctact ttacgcgacc
     1261 gcatgagtac ggagtgcgca tcacgggtcc ggggacggcc tatgaatatg tgtatgatgc
     1321 ggcgcgcgtc gatttgcgga agatcgccta cgattttgaa tatgaactcg acgactggcc
     1381 ggtggatccg caggtctatc aggaattgac cggactgata gaagaatggc agcgccgggc
     1441 tcgcagcaac gaccggccgt tcttgtatta ttcgaaggcc atggagtatg tgaccatcta
     1501 cgacgggcgt gatccggaca tgccgacgag acaacgatac gactggccag cggcggggat
     1561 tattgaggca tgtaatgaag ccgcgaagag tcgcgatcag attcgcgccg cattgggcga
     1621 ggcgaagcgg gacagcatct actcggaaga cgatctgact gaagcgctga gcctcttaac
     1681 cagccgtcgc atcctttacg aagagcgcga gaaatatttc acgctggcta tccccgagca
     1741 tccctattac tgatgggctg gtgaggcaga aagccggcgt tgtttcttgc ctaagctcag
     1801 tacctcaagg tacaggtctc cttcgtctcg gtcctgcacg tgctgcggcc ttgctaggcc
     1861 tcctctttga ccatccactc gtcccattgg ctggcacgtt tctgctgcaa acgcgtcgcc
     1921 gctgaaacat cacatcgaca gcttctccgc cacattgcgc atttggacgc catgcacgag
     1981 tgacgcaccg ccgcggatcg cgcaggcaac gtggacggct tccgtcatct cttcgatgtt
     2041 cgatcctttt tccaggcagg cttgagtata ggcatcgatg cagtacggac actgcacggc
     2101 ttgcgccaca ccaagtgcaa tcagtgcctt ctcccgttcc gtgagggcgc cttcggcaaa
     2161 cacggcgctg taatagctca tgaacttttc ccacaggacg ggattgccct tacccatatc
     2221 tccgaatttc ccaagatcct tcgagtggta gtagcagtcc acggatcacc tcgctggtta
     2281 gtggtctgat catgctcgcg cgtcagccga tgagcatgcg tagtagcggt ctgtgatggc
     2341 gagaagcgtt acgcgtttcc tggaggtgtc ggttcggcct cattgagggc ctgggagaaa
     2401 cggtgtccca cgatggtcgt gaccttgttc atcaattcgc cgagttctct ccactcctcc
     2461 gcactcaaat cggctttgat ctggggatga agggcccatt cggcattcac gagttgcccc
     2521 ttacgcgaga catgcacatg caagagctca acatcccaca catcctgggc gttggcggac
     2581 ggggcggctg gtttctgcgg aggaacttgg cttgccatgc tgcgtgcact cctttgacca
     2641 tacagatgag agggcatgat accgcatcaa atatcgcact gtacatggga cgagcgacgt
     2701 gaatgccaat cgcatcggcc gggtcggata tcaccgctca ggaggttagg acgtggcggg
     2761 tcgttgatgg atgacgtcga gcagttgttg atgaatgagg ccgttggtgg ccacgagctc
     2821 ctgcccatag agagaaaatg tatctttctg aaagccggat accagtccgc ccgcttcacg
     2881 cacgatgacg atcccggcgg ccatatccca agggctgagt ttcacttccc aatatccgtc
     2941 aaaccgccca gaggccacat aactgagatc cagggccgct gagccggtgc gtcgcacgcc
     3001 ttgagcgcgc agcgagatgc gggagaaatg gtccagattg ttattcgtcg tctcgcgaat
     3061 atcgtacgca aatccagtca cgagaagaga acgaccgagg gtctcattgt tcgacacgcg
     3121 gaggcgttcg ccattgaggt aggccccttt gccggcgaca cccgtgaaca gttcctgacg
     3181 agtcgggtcc aggacgacgc ctacgataca gtcgccatga tattccagcc cgatcgagac
     3241 cgaataaaac gggaacccgt gcgcgaagtt ggtcgtgccg tcgagcggat cgatgatcca
     3301 ttgatatggc gactcggtgg ccccgtcccg gccgcgttcc tcggctaaga tccggtgggt
     3361 gggatgagac gaaagaattg aacggacaat acattcctca gcctgccggt cggcatcggt
     3421 cacgaggttg atggcggctt tgtggtcaat tctgaaccct gttttggcat gctcaaggag
     3481 cacgtggccg gctgcttctg ccgcctgaac agccgtggcc agatagcggt ccaattcttc
     3541 agatgggagt gcatgcgacg tatgcataga cgccgtatcc tagcatgagt ggtgtaaagc
     3601 ggggtaaaaa gccttggtca ttttgagaga gcaaattaac atattgaaaa taaatgattt
     3661 aataaaagct tgttcttgca gaacaaggct tggctaggca ctgagtgcat tctgcttgca
     3721 taggcgataa gcgcgaacaa atagttatga tcagttactt gacagatttt gaatcacttg
     3781 ctataaagca agtatgcttt attgaggact tgcttgtgga agaattgacc gacatcctgg
     3841 tgggtctgga gcaacggatc agcgcctacc ggaatcgcta ccaggaactt gagaaaaagc
     3901 gacgtcggct cgacgatgaa atcgcgatga tcaagaagta tctggaactc gccgaaacgc
     3961 tctaccgtgt ggaagcagat aaggccaagt tggccagcct ctcgagtcag attatcaccg
     4021 acgaaaaagg gattcgcccg cttcctgtta cggatgtcac ggaccagtcg cgcgagatct
     4081 tgcttggaaa aagcaagtat gtcgggaaga gtgtgccgga ggctgcgtat caaatacttc
     4141 gagaggcgag ccggccgatg catgcgaagg agctgttgca acggcttttg gagggtggat
     4201 tgcagatcaa gggcaagacg ccattaacct ccgtcgccac ctcgttgaaa cgggataagc
     4261 gtttccagaa agtcggaccc aatacgtttg cggtcacgac gcagcaggaa ttgacagcgg
     4321 tagtgtaagt gggccgagga agttcatatc aactttaatg tgtgaaggga ggtgagagtc
     4381 ttggcaacga agaaggcagc gaagaaacca gcgaagaagg cagcgaagaa gaagtaagtc
     4441 ctgccaggat ttacacgccg ggggtaaggc cacttgcccc cggcgttttt ttatgcccca
     4501 aaaatgaaag atgcttcgat caccgcctgg agccggcgga tcgcacgcgt ggtgaagcca
     4561 tgctgagaga agcagttaga ttgcgaggga cggcgcgggg cgaagcagcc cgagggaagg
     4621 gcgcgattct gatgcagcaa ccgcatgttc cccggtgatc agcgcccatt tgtcgcgctg
     4681 gaggagaatc tgttcgacga gtttcgtatg catggcatgg cctgatcgtt cggccacaac
     4741 gtggccgatg aacgggaagc cgagcagcgc aatgtcacca atgaggtcca gcaccttatg
     4801 ccggacaaat tcattcgaga aacgcaggcc tgattcgttc accacgcctt ctttggacag
     4861 cacgatggtg ttgtccaagg tcccgccctt tccaagtcct ctggaccaga gagcttcgac
     4921 ttcgtgcagg aagccgaacg tgcgtgcctg cgcgatatct tgctcaaacg cctgagcgga
     4981 gcaggtgtag gtgtaggttt gcgtttggat caaggggtga tcgtaatgga tggaatacgt
     5041 aattttcggc gttgacgacg gttcaatcct cacccgtttc gatccgtcca ccacttcgat
     5101 gggttgcata atcttgacat acgattgccg ccgagtctgt gggatgacgc cagccgcgcg
     5161 aatcaaccga acaaacggac ttgagctccc atcgaggacg gggacttccc ctgcattcac
     5221 ctcggcgtag acgttgtcga cttccattcc caccagggcg gcgaggaggt gttcgatcgt
     5281 tttgacctgg tgtccattga cgctgatggc ggtgcagagt tccgtcggga ccttattcga
     5341 gatcgatgca gggatgagtg tttcttctgg gtcatgccga tagatgaaga cgatgccggt
     5401 atttggaggg gccgggcgaa gtgtcagtgt gaccggctgg ccggaatgaa gaccaacgcc
     5461 tgaacatgaa accggtgagc cgatcgtttg ctgaaaccgc acggtgcctc cttcgtaaaa
     5521 tccagcacta nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ggtcttggct
     5641 ccaactcaat gagtcccttt cgaatcgcca aaatcgcggc ttgcgtgcgg tcatacacct
     5701 gaagtttgtg aaaaatgttg cggacgtggt tcttgaccgt cttttcactg aggtccaggc
     5761 tgttggcaat ttccttattc gtttttccgt ctgcgaccaa gcggaggacg gtgatttccc
     5821 gttcggtcag gtcatgttca acccaggccg gcttcttgcc ctttttctga gacatgagtg
     5881 aaaactccgc caggatcttg ctggcgaccg aaggatggat gagcgattcc ccgcgataaa
     5941 tggctcggat tgctgccaca atttgagacg attcggaatc tttcagcaga tatcccgttg
     6001 cccccgcccg tacgagatcg aaaatatatt gctgctcttc atacatggtc agtgcaacga
     6061 ttcccatgtg cgggaattca cgtttgatct gccgcgtggc ttcgatgcct cccatacgcg
     6121 gcatgctgac atccatgagg atgacatccg gcatgagggt cttggttttt tctacggctt
     6181 cgacaccgtc ttgggcttcg ccgacgacgt tgatgtcttc cttcgtcttc agaatagccg
     6241 ccagcccttc acgaactacg cggtgatcat cggcgatcag gaccttaatt ttttccatga
     6301 cgaatcgtct ccttgtcggc tagcgggatg cgcaacacaa tccgcgtgcc gcgtcccttt
     6361 ttcgaatcga tcgtggcttc accgcccacc agtcgcgctc gttccaagat gccacgaatg
     6421 ccgaagtggt cccatttttc aggatcgcgc agcacggcgt ccatgtcgaa cccgatcccg
     6481 ttatcggaaa tggtcacttg taacaggtcg aggcgaatgt cgagttgaac cgacacccgg
     6541 cccgccttgg cgtgcttctg cacgttgctc aacgcttctt ggacgatccg gaataagaaa
     6601 atcttcgtgc gcgggaacag gatcgtctcg tctccggtca cagaaaaggc tgtcttgata
     6661 tggtactgcg tttcgtagga cttcaaatag ttcgtgaggg ccgggatgag ctccatttta
     6721 tcgtagtgga gcggccgtag attgaagatg acctgccgcg cttcttgaat cgctagcttc
     6781 agctgagctt tggattcacg gatcgtcgcc aaactggctt gcgggttttt gcgaagcagt
     6841 tcctgcgaga gctccaactt gaaattgacg ccggcgaggc tttgcaccag gccatcgtga
     6901 atctcgcacg cgatgcgtgt tcgttcttct gtcaccgccg cgccggtctc tttcacgtaa
     6961 agccggtaca acgattggta tttgttcaag gctttctcaa tatcggccgt ggcgcggatg
     7021 cgggcttcga tcagttgcca catgaatttg gcgctggctc cgccgatgac tgaaacgccc
     7081 atgcgacgga tgtcctggag atattcgcca acctcggggt tgcccgacac atcgatcacc
     7141 agatccacgg ggcccatttt gagcaattgc cgataattgc gggtgacgcg aatatgaagg
     7201 cgtttggcga gccccagccc cggcgcttcc ggactgatat cagcgacgcc gacgatgcgt
     7261 accagcgggt cgttggcgaa aatttccatc aaggccgtgc ccccgcg
//
LOCUS       DAOQPD010000119         7170 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_5873_length_7170_cov_22.649754, whole genome shotgun sequence.
ACCESSION   DAOQPD010000119 DAOQPD010000000
VERSION     DAOQPD010000119.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 7170)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7170)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7170
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5873_length_7170_cov_22.649754"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1455
                     /locus_tag="PK063_17605"
     CDS             <1..1455
                     /locus_tag="PK063_17605"
                     /inference="COORDINATES: protein motif:HMM:NF012801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HMZ98922.1"
                     /translation="RRQSDGFRDRSKSQLDDFTMRFEANPDDRTRITTNISWYDETTQ
                     TPGSITPTQYRNDRTLAGKPNDEFKGQRGAIDVTASREIDAHNTAKVIVYGNVFERNW
                     YIQDQAANGTLLSTSTNFLRKFNVFGVMPQHQFKFSLFGLDQQITSGVRYHAERLTDI
                     TGIGTAGSKISRTTNNADLESVAYAAYTETAIRLTEALTISPGIRWEQVNQSRETMNA
                     VPPAGGNFKGYKTTQGLIYGTGVKYQLTPDSMLFGHVHTTFRPPTFANAVDPTSGTTQ
                     DLSAERALSSDVGIRSILVPGVSAEVALFRTEFSNQIVQQGSQFVNAGKTLMEGIEST
                     VSLDWGEIVRPLQGFVTRGSITLLRPKSLFGATDGKDLPYAPRMTFYGLVGYYHPTGA
                     SIEADAMYVAQQFTDGANTQAENALGSNGAIPSYTIWNLRLNYAPPKAKWAIFAGVRN
                     LTDESFIAQRTTGSFIGIQPGEIRNFYGGVSWRF"
     gene            1502..2311
                     /locus_tag="PK063_17610"
     CDS             1502..2311
                     /locus_tag="PK063_17610"
                     /inference="COORDINATES: protein motif:HMM:NF022135.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4198 domain-containing protein"
                     /protein_id="HMZ98923.1"
                     /translation="MNRNLFNSGLWGIVLVAGLWGAVPAQAHFVWVETEATAPADQGQ
                     PVKVYFGEYAEFLREERGGRLDSIDGVTVRVQDPKRGKIDVPLTKQVNHFAGALSSCV
                     PGRNAVVAEQAKAPVQDLRKHDLGIVKPMFYARTYFVCLEESRVNEHERDHSAPLALD
                     LIPLTTGLNLAAGRVTPGPGGEIVVKAIFNGQRLPGTQVLVHAPNGWDKELKTDADGI
                     VSFTPLWPGRYVLEMIHVEKTPGEFEGTAYEALRHRSTLALQVRAERPAEQ"
     gene            2313..3119
                     /locus_tag="PK063_17615"
     CDS             2313..3119
                     /locus_tag="PK063_17615"
                     /inference="COORDINATES: protein motif:HMM:NF015863.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HMZ98924.1"
                     /translation="MSRGGSERIVRLAHRWLGMGSLGFLLLSVVTGLLWADAKFLYWD
                     DHYKEKVRPAANPGIEAARLSVDRAILAAKEAVGGRALVEHVLLRSDFGRVMYELKLR
                     VEGVPTTLLLDAINGERLSPISPDLAPVIAQQYVRTPAAVTGVELERYTPRKKKRAQD
                     AVRVRFDNADATEIVLDRQTGEILEDEGRWRRVHFAVMQLHQLNFFGFEKTLLNIPGV
                     PILLMSLSGCLLWIFHRARMRRAQLAPVSRETGLFPARSTGEPKEVPPLG"
     gene            3193..5226
                     /locus_tag="PK063_17620"
     CDS             3193..5226
                     /locus_tag="PK063_17620"
                     /inference="COORDINATES: protein motif:HMM:NF014763.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ98925.1"
                     /translation="MTIRTIKGRIVLAIVMVGCIPLLISLVLAYMSGMRSLRDVIGGN
                     FQAIAEQAADRLTMLVQSEVQGVRLLASAPLRVRQPVEAANLSYKGEWADTQRLIQER
                     AKEWEKGHDNAAGLLNLELSRFLLETKVRNGDKMVGLLITDRYGALVAASSEPDHYFL
                     SQEPWWEALQAGGLDRVYVSGLIPGQEGSFRSPEETIDIAVPILDDHQHAVIGAIKAS
                     YRFDSLFAMIKEIRIGQTGHAMLFDAAGQPLVCPILPRRAHRIPGQLMAMIVSSNPGW
                     GIAEDDGHGATDTVVGYAPVTGLSLPDNSWHVFVRQQPEETYAPIRDQLRNLALIGVV
                     MSGLLWAMGRYVATRIARPIQVLKTGVEAISRGTYDGPLDVKTGDEFEDLAVAVHRMA
                     DRLQASRIELESLNAELTHRVEEKTAEITRQMRKLELSERLATLGKVASGIAHEINNP
                     LGIILNRIECMEADAAQSNVPDEVGRDLVTIRTQAERISRVTRSILTFSRGTVSMLKP
                     LDLNCVARTCVAMAGERMTGLAVRMDLETAAALSPVMGDRDRLETVLLNVINNAIDAV
                     TASGEQGVVTIRTARVQINGDEWVQISISDTGPGVPSAIADRIFDPFFTTKPAGQGTG
                     LGLFLSYGIVSDHRGRIEVRNDSVGAVFDIYLPAVGLGESVHEGAPWGLQEKF"
     gene            5202..6620
                     /locus_tag="PK063_17625"
     CDS             5202..6620
                     /locus_tag="PK063_17625"
                     /inference="COORDINATES: protein motif:HMM:NF025885.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ98926.1"
                     /translation="MGIAGKILIVDDEQDALDNCRRILSRVPYDCLTECDPSRALEII
                     QRERPGLILTDLRMPQLDGIEVLAAAKRMDPSVQVVLLTAHATVQTAVTSMRYGAFDY
                     ITKPFTSRDLVQVARRAFGEDESTGAKQVGATEVRPPVDHGRQGTRATCARVIGESPA
                     MESVFSLIDKVAPTHSNVLVYGESGTGKELVARAIHDASLRADRPFIPVDCVSLPDTL
                     LESELFGHEKGAFTGAHVSKPGLFEVAAGGTVFLDEVSGMSQTLQSRLLRVLQERQMR
                     RVGGIRFLDVDVRVIAASNQDLEAACRRGEFREDLYYRLNVIPIVLPPLRSREGDIPI
                     LAQEFLRRFVKQQGAALGFVPNLDSTATELLCGYAWPGNVRELQNVIERAAVLADGPL
                     ITAAHLPERLRQVVVDEAGPGEAGSFKHAKQAAVTTFERSFLMELLKRNDGHMGRAAR
                     EAGVDRKTVERMVKKHGLRERS"
BASE COUNT         1442 a         1926 c         2288 g         1514 t
ORIGIN      
        1 cggcgccagt cagacggatt tcgagatcga agcaaatcgc agttagatga tttcacgatg
       61 cgattcgaag ccaatcctga cgatcggacg cggattacga cgaatatttc atggtacgac
      121 gaaacgacgc agacccctgg aagcatcacg cccacgcaat accgaaacga tcgtacgctg
      181 gcaggcaaac cgaacgatga attcaaaggg cagcggggag cgatcgacgt gacggccagc
      241 cgggaaatcg acgctcacaa caccgccaag gtcatcgtgt acggcaatgt cttcgagcgg
      301 aactggtata tccaggacca ggctgccaac ggcacgctgc tctccaccag cacgaacttt
      361 ttgcgcaagt tcaatgtctt cggcgtcatg ccgcaacatc agttcaaatt ttcgctcttt
      421 ggattggatc agcagatcac gtccggtgtt cggtatcacg ccgaacgact gaccgacatc
      481 accggtatcg ggacagccgg ctcaaagatc agtcgcacga cgaacaatgc cgatctggaa
      541 tcggtggcct atgccgccta tacggaaacg gcgattcgtc tgaccgaggc cctcaccatt
      601 tcgccgggca tacgctggga gcaggtcaat caaagtcgtg agacgatgaa cgccgttccg
      661 ccggcgggag ggaatttcaa gggttacaag acgacgcaag gactgattta cgggaccggc
      721 gtcaagtatc aactcacccc ggacagcatg ctgtttggcc atgttcatac gaccttccgc
      781 ccgccgacct tcgccaatgc ggtcgatccg acgagcggca ccacccaaga tctctccgca
      841 gaacgcgcgt tgagttccga tgtcggaatc cggtccatcc tggtgcccgg ggtgagtgcg
      901 gaagtcgcgt tgtttcgcac cgaattcagt aatcagattg ttcagcaggg cagccagttc
      961 gtgaatgccg gaaaaacgct gatggaggga atcgagagca ctgtcagtct cgattggggt
     1021 gaaatcgtcc gcccgctcca aggcttcgtc accagaggca gcattaccct cttacggccg
     1081 aaatccctct tcggagcgac ggacgggaaa gaccttccgt acgccccccg catgacgttc
     1141 tacggcttgg tgggatatta ccacccgacc ggtgcatcga ttgaagccga tgccatgtat
     1201 gtcgcacagc aatttaccga tggcgcgaat acccaagcgg aaaatgcctt gggttcgaac
     1261 ggtgccatcc cttcctatac gatttggaat ctccggctca attatgctcc gccgaaggcg
     1321 aagtgggcca ttttcgccgg tgtgcgcaac ctgacggatg aatcattcat cgcccaacgt
     1381 accaccggca gttttatcgg catccagccc ggtgaaatcc ggaacttcta tggcggggtc
     1441 tcctggagat tttgatggga agtcgcaacc tttgagcgaa cttcagaaag gaatgacgct
     1501 gatgaatcgg aacctattca atagtggatt gtggggaatc gtattggtgg ccgggctgtg
     1561 gggcgctgtt ccggctcagg ctcatttcgt ctgggtggaa accgaagcga cggctcccgc
     1621 ggaccagggg caaccggtga aagtgtattt cggcgagtat gcagaatttc tccgggaaga
     1681 acgtggggga cggctcgatt ccattgatgg cgtcactgtg cgtgtgcagg atccgaagcg
     1741 agggaagatc gatgtcccgt tgacgaagca ggtgaaccac tttgctggag ccctgtcatc
     1801 ctgtgtaccg gggcggaacg cggtggtcgc ggagcaggcg aaagcgccgg tgcaggatct
     1861 gcgcaagcat gacctgggca tcgtcaagcc gatgttctat gcgcggacct atttcgtctg
     1921 cctggaagaa agccgggtca acgagcatga acgtgaccac tcggcgccgt tggccttgga
     1981 tctgatcccg ctcacgacgg ggctgaattt ggcggcgggc cgcgtcactc ccggtcccgg
     2041 gggcgagatc gtggtgaaag cgatcttcaa cgggcaacgc ctgccgggga cgcaggtgct
     2101 ggtgcatgcg cccaatggct gggacaagga gctcaaaacg gatgctgacg ggattgtgtc
     2161 cttcaccccg ctgtggccgg gccggtacgt gttggagatg attcatgtcg aaaaaactcc
     2221 gggcgagttc gagggaacgg cgtatgaggc cttgcgccat cgcagcacgc tggcgcttca
     2281 ggtgagggcc gagcgcccgg cggagcaata acatgagtcg cggcgggtct gaacggattg
     2341 tgaggctggc tcatcgctgg cttggcatgg gctccctggg ctttctgttg ctctcggtcg
     2401 ttaccggcct gttgtgggcg gacgcgaagt ttctctattg ggatgaccat tataaggaga
     2461 aggtccggcc agcggcgaac cctggcatag aagcggcgag gctatccgtg gatcgtgcga
     2521 ttctcgccgc caaggaggct gtgggaggac gggcattagt cgagcacgtg ttgctgcgat
     2581 cggattttgg ccgcgtgatg tatgaactca aattgcgggt cgagggggtg ccgaccacgc
     2641 tcttgctcga tgccatcaac ggtgagcgcc tgtctcccat ttcaccggat ctggcaccgg
     2701 tgattgcaca gcagtatgta cggaccccgg cagccgtgac gggcgtggaa ctcgaacggt
     2761 ataccccgcg caagaaaaag cgggcacagg atgcggtgcg ggtgcgattc gataatgccg
     2821 atgccactga gattgtgctg gatcggcaga caggcgagat cctggaagac gaaggacgct
     2881 ggcggcgcgt gcattttgcc gtgatgcaat tgcatcagct gaatttcttt ggctttgaaa
     2941 agactctctt gaacattccc ggcgtgccga ttctcttgat gagtctctcg ggatgcctgt
     3001 tatggatctt tcatcgtgcc aggatgcggc gagcgcaatt ggcccccgtc agcagggaga
     3061 cggggttgtt tcctgcccgt tcgacgggcg aaccaaagga ggtgccaccc ctgggttgat
     3121 catcggccgg gttgaccctg cggtggcgtt ttcttccgcc ggttgtttag aatgtcctca
     3181 ctgaggtggg gaatgacgat tcgtaccatc aagggtcgca tagtgctcgc catcgtgatg
     3241 gtgggctgca ttccgctcct gatcagcctc gttctggcct acatgtccgg catgcgctcc
     3301 cttcgcgacg tcatcggcgg gaattttcaa gcgatcgccg agcaggctgc cgatcgtctg
     3361 acgatgctcg tgcagagcga agtgcaggga gtgcggttgc ttgcgtccgc gccgttacgt
     3421 gtccgtcagc cggtcgaagc cgccaatctg tcctacaaag gggagtgggc cgatacgcag
     3481 cggctgattc aggaacgcgc gaaggagtgg gagaaaggac acgacaacgc tgcgggccta
     3541 ttaaatttgg aactgtctcg atttcttctc gagacgaaag tccgtaacgg cgacaagatg
     3601 gtggggttgc tgatcaccga ccgttatggg gcattggtcg cagccagttc cgaaccggat
     3661 cattacttcc tcagccagga accgtggtgg gaggccttac aagccggagg cctcgaccgt
     3721 gtgtatgtca gcgggctaat tcccggccag gaaggatcgt ttcgctcgcc tgaagagacc
     3781 atcgacatcg cggttcccat tcttgacgac catcagcacg cggtcatcgg tgcgattaag
     3841 gcctcttatc ggttcgactc tctgtttgca atgatcaaag agatccgcat cgggcagacg
     3901 gggcatgcca tgttgttcga tgccgccggc cagccgttag tgtgccctat cttgcctcgt
     3961 cgcgcacatc ggattccggg ccagttgatg gcgatgatcg tctcgtcgaa cccaggctgg
     4021 ggcatcgccg aggacgacgg ccatggcgcg accgacacgg tcgtggggta tgcgcctgtc
     4081 acgggtttga gtctgccgga caactcctgg cacgtcttcg tgcggcaaca gccggaggaa
     4141 acctacgcgc ccattcgcga ccagttacga aatctcgccc tgatcggtgt cgtgatgtcg
     4201 ggcttgctct gggcgatggg gcggtacgtc gccaccagga ttgcccggcc gattcaagtg
     4261 ctcaagacgg gcgtggaggc gatcagtcgt ggcacctacg atgggccact cgacgtcaaa
     4321 accggtgatg aattcgagga cctggccgtc gcggtgcatc gcatggcgga tcgattgcag
     4381 gcgtcgcgta tcgaactgga gtcgctgaat gccgaactca cacatcgggt ggaagagaag
     4441 acggcggaga ttacacggca gatgcgaaaa ttggaactgt cggaacggtt ggcgacgtta
     4501 ggcaaagtgg ccagcggaat cgcgcatgag atcaacaatc cactcggcat cattctcaat
     4561 cgcatcgaat gtatggaagc tgatgccgcc cagtcgaacg tcccggatga ggtcggtcgc
     4621 gatctcgtca cgatccggac ccaggcagaa cgaatttccc gcgtcacgcg aagcattctg
     4681 acgttttccc gaggtacggt gtccatgctg aaaccgctcg acttgaattg cgtggcacga
     4741 acgtgcgtgg ccatggcagg cgaacgaatg acgggtcttg ctgtgcggat ggacttggaa
     4801 acggccgcgg cgttgtcgcc ggtgatgggt gatcgtgatc gattggaaac cgtgttgctg
     4861 aacgtgatca ataatgcgat tgacgcagtg acagcatctg gcgagcaggg agtggtcacg
     4921 atccgtaccg ctcgcgtgca gatcaatgga gatgagtggg tgcagatcag catatcggac
     4981 actggacctg gggtgccctc ggcgattgct gatcggattt ttgatccgtt ttttacgacc
     5041 aagccggccg gccagggaac cggcttgggg ctatttttga gttatggcat cgtctcggat
     5101 catcgcgggc gcatcgaggt gcggaacgat agcgtgggcg ccgtctttga catctatctg
     5161 cctgcggtgg gactgggcga gagcgtgcac gaaggagcac catggggatt gcaggaaaaa
     5221 ttctgatcgt cgatgacgag caggatgcgt tggacaattg caggcggatt ctcagccgtg
     5281 tgccgtatga ctgcctgact gagtgtgatc cgtcgcgggc gctggaaatc attcagcgcg
     5341 agcggcccgg gttgatcctg acggatttgc gaatgccaca actggacggc atcgaagtgc
     5401 tggctgcagc taagcgaatg gatccctctg tccaagtggt attgttgacg gcgcatgcga
     5461 ccgtgcagac cgcggtgacg tcaatgcgct atggcgcctt cgactacata accaagccat
     5521 ttaccagtcg cgaccttgtc caagtggctc gccgcgcatt cggtgaggat gagtcgactg
     5581 gtgcgaagca agtcggggca accgaggttc gacctcccgt cgatcacggg cgtcagggaa
     5641 cgcgggccac ttgtgcacgg gtcattggtg agagtccagc catggaatcg gtcttcagcc
     5701 tgattgacaa agtggcgccg acgcattcca acgtgctggt ctacggggaa agcgggacgg
     5761 gaaaagaact tgtcgcgcgc gcgattcacg acgccagttt gcgggccgat cgccccttca
     5821 ttccggtgga ctgcgtctcg ttgcctgata cgctccttga atcggaactg ttcggccacg
     5881 agaagggcgc cttcaccggc gcacacgtct cgaagcccgg gctgttcgaa gtggcggcgg
     5941 gcgggaccgt ctttctggac gaggtcagcg ggatgagcca gaccctccag tcgcgattgc
     6001 tgcgggttct tcaggagcgc cagatgcggc gggtcggggg catccggttc ctggatgtcg
     6061 acgtgcgggt gattgccgca tcaaaccagg atctcgaggc cgcctgccgg cgcggagagt
     6121 ttcgcgagga cctctactat cgcctgaatg tcattcccat cgtgttgccg ccgttgcgga
     6181 gccgggaggg tgatattccg attctggccc aggaattttt gcggagattc gtgaagcagc
     6241 agggggccgc cctcgggttc gtccccaacc tggactccac ggcgacggag ttgctgtgcg
     6301 ggtatgcctg gccggggaat gtgcgcgaat tgcaaaacgt cattgaacga gctgccgtgc
     6361 tggccgatgg tccgctgatt accgccgcgc atttgcccga gcggttgcgc caggtggtgg
     6421 tggacgaggc aggaccggga gaggctggct ccttcaagca tgcgaagcaa gcggcggtca
     6481 cgaccttcga gcggagtttt ctgatggaac tgctcaagcg aaacgatggc catatggggc
     6541 gagccgctcg ggaagccggg gtggatcgaa aaacggtcga gcgcatggtc aagaagcatg
     6601 ggctccgcga gcgctcctga tccgttttct gtcacggcgt accgtggtta ttcacgatgc
     6661 ctgattcggg gtttccccct cagttttcaa ttggggcatc aatgtcccat tgggacaaat
     6721 gttccggaca ctcaccgttc gcctttcagt tcgcagcatt cctgagaatt gtggtttttt
     6781 gatggggcga cgtcgcccca tttttattct ctccttcatc ttcactgtct gaaattccca
     6841 acaaagtctg cgtttcctgg acccaatgaa tctggaacgg gagttgctct gtaactcgcc
     6901 gtcttttcat gcgcattgct tttcatgcgc gttgtgaagt gcgccatcgt cttgttatcg
     6961 cggatcaaag gtgtggaaac cgaaggaccg gcctcctggt gtttccactc catgaggtgc
     7021 aggtcttcac gggcctgcac cgtgcgcgac cggagtgcga tggcaagaga gtggggatgc
     7081 ggaggttgta tggtttcaag aggaggtagg tctaatgaga tcggtacgta gcgggcctaa
     7141 gaaactcagt cagcgcaggt cccaagcggc
//
LOCUS       DAOQPD010000120         7163 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_5888_length_7163_cov_21.456246, whole genome shotgun sequence.
ACCESSION   DAOQPD010000120 DAOQPD010000000
VERSION     DAOQPD010000120.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 7163)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7163)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7163
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5888_length_7163_cov_21.456246"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            101..1312
                     /locus_tag="PK063_17630"
     CDS             101..1312
                     /locus_tag="PK063_17630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HMZ98927.1"
                     /translation="MSTFTYVGRNRQGAVKKGELTAKTRDEAVDQLRKQQVVVTSLEE
                     KSGGKLKLNLGGGLTDKDLVVFTRQFGTMINAGLPLIQCLDILSTQSENKVLRETVGD
                     VKNSVEAGSTFSDALKRHPKVFDDLYVNMIHAGEVGGLLDTILTRLAKHIEKAMKLKG
                     QIKSAMVYPTAIVGVAVVIISVLMVWVIPVFAQMFTEMSGGKVGLPGPTQIVINVSNF
                     FQSYWYAMFGAVAGTIFAIKRYYATVNGRVVIDKLLLKMPIVGDLIRKASVAKFTRTL
                     GTLITSGVPLLEGLSICAKTSGNKVIEEALMNARVSISGGKTISEPLAKCNVFPKMVT
                     HMIAVGESTGALDAMLGKIADFYEDEVDQAVETLTSLLEPIMMVVLGTIIGFIVVAMY
                     LPIFTMAQAIQ"
     gene            1483..3213
                     /locus_tag="PK063_17635"
     CDS             1483..3213
                     /locus_tag="PK063_17635"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ98928.1"
                     /translation="MLDERPLPSGERSMPELKTRLHWLMGLRVAIVTVMLGLSLAFQS
                     TRGESAPTFTALIVFTYTITIVYALVLRRLTTAVAYTAFIWVQVGVDVILETVLIART
                     GGVESPFAVLYVITVTVASLVPHRRVGIVTGAGCTLLFGSITAVQYFGLLNASGWLPP
                     SKLEGPEALQTFEVYGLAFLVVGYLSGVLADELRHADQSLREKEQGLSRLQVFHESIV
                     RSISSGVFTTDQEGRITSFNPAAHEVTGYAFSDVQGRLWQEVFNWHPDGRSQDTDVAS
                     PPLRFEVDCFHANGSCLVLGMTVSPLQEQGTQRGLVGVFKDLTQIRYLEEEMRRREWL
                     ANLGEMSAGMAHEIRNPLGALAGAMQMLRQDVGSDETSQKLMDIAIREARRLDNIITE
                     FLQYARPPALNLAEQDLNKVLADTLDLIQHEARSRTGITIVSRPTPIALRAKVDQDQL
                     KQVFWNLSVNAFDAMPGGGTLTITTGLRRVEVGGRREDVIEISVHDSGEGIPKQNFDK
                     IFLPFFTTKKEGSGLGLAQVHRIVELHDGWIKVESEVGTGARFVVCLPQSPEVGVRLR
                     HEGREPWKRF"
     gene            3198..4577
                     /locus_tag="PK063_17640"
     CDS             3198..4577
                     /locus_tag="PK063_17640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="HMZ98929.1"
                     /translation="MEKILVVDDEQGLRDVLSIMLKRAGYAVTVASDGEEAIAQIHKE
                     IFDLVITDLKMPKMGGLDVLKAVKASSPDTVVLMITAFASADSAVEAMKHGAYDYLTK
                     PFQVDEVQLIIRNAIERRRLSTENMLLKRELASQSSFSQIVGQSEAMQKVYDVIKKVA
                     DSRSNVLIGGESGTGKELVARAIHFNSARASMPFVTVNCSAVPETLLESELFGHMKGS
                     FTGAVSNKAGLFEVANGGTIFLDEIGDTTPAIQVKLLRVIQEREFRRVGGTQDVKVDV
                     RIVAATNRDLEKAVAEGAFREDLYYRLDVIPIRLPPLRMRTGDIPLLSQHFLEKFAKE
                     SGKPVPTMSQEAMRVLLAHEWRGNVRELENVVERVVAFTTGSSVTDADIRGWLHKPVS
                     TQQAVPSELPEDGLDLEGLINTIEKDLLLKALERSQWVKKRAARLLRLNTRSFRYRLE
                     KYEIKGGRD"
     gene            4598..5497
                     /gene="ispE"
                     /locus_tag="PK063_17645"
     CDS             4598..5497
                     /gene="ispE"
                     /locus_tag="PK063_17645"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: protein motif:HMM:TIGR00154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HMZ98930.1"
                     /translation="MNSTSLLVLTPAKVNLILRVLERRPDGFHAIWSLMHTVGLNDEL
                     MLTMQPAAASRITLRCNQADLAVDQTNLVYRAAELVLARANRTMDLSISLTKRIPMGA
                     GLGGGSSDAAATILGLTRLLELNWSVEQMAEVGQQLGSDVPFFFVAPAACVTGRGEHV
                     RPVRVTGNRWIVLVSPGFPVPTKWAYQQLAATRAGVRPLSVAVQSLDQRSELDWSEIV
                     PLVENDFEEPVFAHHPVLAQIKSQLLSLGAEVALLSGSGATMFGLFREQSAAQQAADV
                     FGRNPGMTAYAVPAAGAPTTTVV"
     gene            5796..6737
                     /locus_tag="PK063_17650"
     CDS             5796..6737
                     /locus_tag="PK063_17650"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0006015 - 5-phosphoribose 1-diphosphate
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009165 - nucleotide biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HMZ98931.1"
                     /translation="MNRELKLFSGNANPALARAIGTYLDLPIGAATVSSFSDGEIRVR
                     IEENVRGADVFLIQSCCAPVNDSIMEMLIMIDALKRSSANRITAVIPYFGYARQDRKD
                     QPRVPISAKLVADLVTTAGADRVLTMDLHASQIQGFFNIPVDNLYALPVLLDYITKRR
                     IEDLVVVSPDAGGVERARAFAKRLQANLAIIDKRREGPNQAQVMNIIGDVQGKSALLL
                     DDMIDTAGTIVQGAQACLDKGAREVWAGCSHGVLSGPALERLQQSGLTDVLVTDSIPL
                     RGKEQKCPKLKVLSVAPLFGEAIRRIHEDESVSSLFV"
     gene            6775..>7163
                     /locus_tag="PK063_17655"
     CDS             6775..>7163
                     /locus_tag="PK063_17655"
                     /inference="COORDINATES: protein motif:HMM:TIGR00731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25"
                     /protein_id="HMZ98932.1"
                     /translation="MKFELTVESREGGGKGPARQLRRAGRVPAVLYGQGECLLLSVKP
                     DELVKVLRSQAGSTALISLTINGAKSKPNRTALLREFQVDPITSSVLHADFFEVAMDK
                     PIRVKVPIHLTGGQPIGLKEGGVLHQA"
BASE COUNT         1459 a         1930 c         2233 g         1541 t
ORIGIN      
        1 ttgtttgaca gtttttaggt cgtcttatag acttcgatca tagttttccg ctgcacacct
       61 acgtgttctg cctggcgttc aaaggagtga aaaccgcgtt atgagcacat tcacctacgt
      121 cggacggaac cgccagggtg ctgtaaagaa gggggaactc accgccaaaa ccagagatga
      181 ggcggtggac cagcttcgca agcagcaggt cgtggtcacc agcctggaag agaagtcagg
      241 cgggaaactc aagctgaacc tcggcggagg cctcaccgac aaggatctcg tggtgttcac
      301 tcgccagttc ggcacgatga tcaatgccgg actgccgctc attcaatgtc tcgatattct
      361 atccacccaa tcagaaaata aagtgttacg cgaaacggtc ggcgacgtga agaacagcgt
      421 cgaggccggc tccacattct ccgacgcctt gaagcgccat cccaaggtgt tcgacgatct
      481 ctacgtcaac atgatccatg ccggtgaggt gggcggtctg ctcgatacca ttctgacccg
      541 attggccaag cacatcgaaa aggccatgaa actgaagggc cagatcaagt cggcgatggt
      601 ctatcccacg gcaatcgtcg gtgtagcggt cgtcatcatc agcgtgttga tggtctgggt
      661 cattccggtg ttcgcgcaga tgttcacgga aatgtccggc ggtaaggttg ggcttcccgg
      721 cccgacgcag attgtcatca atgtcagcaa tttcttccag agctattggt acgccatgtt
      781 cggcgccgtc gcaggcacca tcttcgcgat caaacgctac tacgccacgg tcaatggacg
      841 cgtggtgatc gacaagttgc tgctgaagat gccgatcgtc ggagatttga tcagaaaagc
      901 ctccgtggcg aaatttaccc ggaccctcgg caccttgatc accagcggtg tgccgctatt
      961 ggagggactg agtatctgcg ccaagacttc gggcaacaaa gtgatcgaag aagcgctcat
     1021 gaacgcgcgg gtgagtatca gcggcggaaa aacgatctcc gagccgctgg ccaaatgtaa
     1081 cgtgttcccg aaaatggtga cgcacatgat cgccgtcggc gaatccaccg gtgcgcttga
     1141 tgccatgctc ggtaagatcg ccgatttcta tgaagatgaa gtggaccagg ccgtcgagac
     1201 cctgacctcg ctcctggaac cgatcatgat ggtggtcttg ggtaccatca tcggctttat
     1261 cgtcgtcgct atgtacctgc cgatcttcac gatggcgcag gccatccaat aacgacgcga
     1321 cccgatcgcg tctcgtatct ggcgcacgac cctgaccatc cgaagggccg tgcgccgcac
     1381 atccatcatc agggcaacgc gcccggcatg ctgtcctcaa cgcttccagc cgcaactgac
     1441 gcttccgagc aatcccgcag cccgcaggac tcgatgtctc ccatgctgga tgaacgtcct
     1501 ctgccctcgg gcgaacggtc gatgccggag ttaaagacac gactccactg gctcatgggg
     1561 cttcgcgtcg ctatcgtgac ggtgatgctc ggcctctccc tggcctttca gtcaacgcgt
     1621 ggcgaatcgg caccgacttt caccgcgctc atcgtcttca cctacaccat taccatcgtg
     1681 tatgcgctgg tgctgaggcg gctgacgacg gcggtggcct atacggcgtt tatctgggtg
     1741 caagtcggag tggatgtgat cctcgaaacc gtcctgatcg cgagaaccgg cggcgtcgag
     1801 agtccttttg ccgtgttgta cgtcatcacg gtcacggtgg ccagtctcgt gccgcaccgg
     1861 cgtgtcggca ttgtcacggg tgccgggtgc accttgttgt tcgggtctat cacggctgtt
     1921 caatatttcg ggcttctgaa cgcctccggc tggctgcctc ccagtaaact cgaaggacca
     1981 gaagcgttgc agaccttcga agtgtacggg ctcgcatttc tggtcgtcgg atacttgagc
     2041 ggagtcctgg ccgacgagct tcgtcacgcc gatcagtcgt tgcgagagaa ggagcagggt
     2101 ctcagccggc ttcaggtgtt ccatgagagc atcgtgcgca gcatcagcag cggagtgttt
     2161 acgaccgatc aggaagggcg gatcacctcg ttcaatcctg ccgctcatga agtgaccggc
     2221 tatgcgtttt cggacgtgca gggtcgcttg tggcaggaag tgttcaattg gcatccggat
     2281 gggcgatcgc aggataccga cgtggcttcg ccgccgttgc gctttgaagt ggactgcttt
     2341 cacgccaacg gtagctgtct ggtgttgggg atgaccgtct cgccgcttca agagcagggt
     2401 acgcagcggg gtctggtcgg ggtgttcaag gatctcacgc aaattcgtta tctggaagag
     2461 gaaatgcgcc ggcgggaatg gctggccaat ctgggtgaga tgtcggccgg tatggcccat
     2521 gaaatacgta atcctttggg tgcgctggcc ggcgcgatgc agatgttgcg gcaggatgtc
     2581 ggctccgacg agaccagcca gaaattgatg gacatcgcca tccgggaagc caggcggctc
     2641 gacaatatca tcacggagtt tctacagtat gcgcgcccgc cggccttgaa tctggctgag
     2701 caggatttga ataaagtcct tgccgatacg ttggatctga tccaacatga agcgcgatca
     2761 cgaaccggca tcacgatcgt gtctcgtccg accccgattg ctctccgggc aaaggttgac
     2821 caggatcagt tgaagcaggt gttctggaat ttgtccgtca atgcgtttga cgccatgccc
     2881 ggaggaggaa ccctcacgat tactaccgga ctgcgccgcg tggaagtcgg aggacgccgc
     2941 gaggatgtga ttgagatcag cgttcacgat agcggcgaag gcattccaaa gcagaacttc
     3001 gacaagattt ttcttccatt tttcacgacg aagaaagagg ggtccgggtt gggtctggcc
     3061 caggtccatc gcatcgtgga gttgcacgac ggatggatca aagttgagag cgaagtgggc
     3121 accggggcgc gttttgtcgt ctgcctcccg cagtccccgg aggtcggcgt gcgtttgcgg
     3181 catgagggaa gggaaccgtg gaaaagattc tagttgtcga cgatgagcag ggtctgcgcg
     3241 atgtgttgag catcatgctc aagcgggcgg ggtacgccgt aaccgtggcg tcggacgggg
     3301 aagaggcgat cgcgcagatt cataaagaaa tttttgatct cgtcatcacc gacctcaaga
     3361 tgccgaaaat gggtggcctg gacgtgctca aggccgtcaa ggcctcatcg cctgacaccg
     3421 ttgtgttgat gatcacggcc tttgcctccg ccgattccgc agtcgaagcc atgaagcacg
     3481 gcgcgtatga ctatctcacc aagcctttcc aggtcgatga agtgcagttg atcattcgca
     3541 acgcgatcga gcggcgccgg ctgtcgacgg agaacatgct cctgaagcgg gaattggcca
     3601 gccagtcgtc gttctcccag atcgtgggcc agagcgaggc catgcagaag gtctacgatg
     3661 tcatcaagaa agtggcggat tccaggagca acgtcctgat cggcggggaa agcggcaccg
     3721 gcaaggagtt ggtggcgcga gccatccatt tcaacagtgc gcgagcctcc atgccgttcg
     3781 tgacggtcaa ttgcagcgcg gtgccagaaa cgctgctcga aagtgaactg ttcggccaca
     3841 tgaagggctc cttcaccggc gcggtttcca acaaggccgg tctgtttgag gtggcgaacg
     3901 gcggcacgat tttcctcgac gagatcggcg ataccacgcc tgcgattcag gtcaagctct
     3961 tgcgcgtcat tcaggagcgg gagttccggc gggtcggcgg cacgcaggat gtgaaagtgg
     4021 atgtgcgtat cgtggcggcc acgaatcgtg acttggaaaa ggcggttgcc gaaggcgcat
     4081 ttcgtgagga tctctactat cggctcgatg tgattccgat caggctcccg ccattgcgca
     4141 tgcgaaccgg cgacattccg ctactgagcc aacattttct cgagaaattt gccaaggaaa
     4201 gtggtaaacc agtgccgacg atgagccagg aggccatgcg cgtgctgttg gcgcatgagt
     4261 ggcggggcaa cgttcgtgaa ttggagaacg tcgtcgaacg cgttgtggcc ttcaccacgg
     4321 gatcgtcggt gacggatgcg gatattcgcg gatggctcca taagccagtg agcacccagc
     4381 aggctgtgcc ctcggaattg ccggaagatg gcctggatct ggaggggttg atcaacacga
     4441 tcgagaagga tctgctgttg aaagcgctgg agcggagtca gtgggtcaaa aagcgagccg
     4501 cgcgactgct gcggttgaat acccggtcgt tccggtaccg tctcgaaaag tatgaaatca
     4561 aaggaggccg ggattagcgc cgccctgtta gctgcgagtg aactctacta gtctgctggt
     4621 tctgactcct gccaaggtca atctcattct ccgggtgctc gaacgacggc ctgacggttt
     4681 ccatgccatc tggtcattga tgcatacggt ggggctcaac gatgagttga tgctcaccat
     4741 gcagcccgct gccgcctccc gcatcacctt gcgctgtaac caggccgacc tggcggtgga
     4801 tcagaccaat ctggtctatc gtgccgcgga gctggtgttg gcgcgagcca accggacgat
     4861 ggatctctcc atcagcctga caaagcgcat tcccatgggg gccggacttg gtggaggaag
     4921 cagtgatgcc gccgcaacca ttctcgggtt gacccggttg ttggaattga actggtcggt
     4981 cgagcagatg gcggaggtgg ggcagcagtt aggaagtgat gtgccgttct tttttgtggc
     5041 gcctgccgcc tgtgtgacgg gacggggaga gcatgtccgt ccggtccgag tcacgggaaa
     5101 cagatggatc gtgctggtca gtccgggatt tcctgtgccg accaaatggg cgtatcagca
     5161 gttggctgcc acccgcgccg gtgtgcgtcc gctctcggtg gcggtgcagt ccttggatca
     5221 acgctccgag ctggattggt cggagattgt tccgttggta gaaaacgatt tcgaggagcc
     5281 cgtgttcgct caccatccgg tgctggcgca gattaagagc caattgctga gcttgggcgc
     5341 cgaggtggcc ctgttatccg ggagcggagc gaccatgttc ggcctgttcc gagagcagtc
     5401 tgccgcacag caggcggcgg atgtgttcgg gcgcaatccc ggaatgacgg cctatgcggt
     5461 gccggcagcc ggcgctccga cgacgacggt ggtgtgaaga gagacgctga tagaggttga
     5521 atcggggtct cccgtgtgta ggaaacgacc ctatctggag caccacggtc acgacagacc
     5581 ggcactcact ttcctcggcc cccagcccgt cgcagattat tgacaacttc ccagggtttt
     5641 cgttaatgtg ctgtgcttcg gtaggcgtcc tcttgtcctg acagtgccag gtcggcagga
     5701 ttaatagcgg tccgttccgt gcccaccgtt tttgaacgac tcgatacgca ccgttacagc
     5761 atcggcatcg ccacgtaccg catcgaaggg gtggaatgaa cagggaactg aagctctttt
     5821 cgggcaacgc caatcctgcg cttgcgcgcg cgatcggcac gtatctcgat ctgcccatcg
     5881 gcgcggccac ggtctcctcg tttagtgacg gggaaatccg cgttcgcatc gaagagaatg
     5941 tgcgcggggc agacgtgttt ctcattcagt cgtgctgcgc gccggtcaat gattcgatca
     6001 tggaaatgct catcatgatc gatgccctca agcgttcgtc ggccaatcgc atcaccgcgg
     6061 tcatcccgta tttcgggtat gccaggcagg atcgtaagga tcagccgcgc gtgccgattt
     6121 ccgccaaact ggtggcagac cttgttacca ccgccggcgc ggaccgggtg ctgacgatgg
     6181 atctccatgc cagccaaatt cagggttttt tcaatatacc cgtggataat ctctacgcct
     6241 tgccggtgct attggattac atcaccaaac gaagaatcga ggatctggtc gtggtgtcgc
     6301 ctgatgctgg cggcgtggaa cgtgccagag cctttgcgaa acgtctgcag gccaatctcg
     6361 ccatcatcga taaacggcgg gagggaccga atcaggctca ggtgatgaat attatcggtg
     6421 atgtgcaggg gaagagcgcc ttgcttcttg acgatatgat cgataccgcc ggcaccattg
     6481 tgcagggtgc tcaggcttgt ttggataaag gcgcgcgaga ggtgtgggcc ggttgttcgc
     6541 acggcgtatt gtctgggccg gcgttggagc gtctccaaca atcgggattg actgacgtgc
     6601 tggtgaccga ttcgattccc ttgcgtggca aggagcagaa gtgtccgaag ttgaaagtgt
     6661 tgtctgtggc gccgctgttt ggcgaagcca tcaggcgtat ccatgaggat gaatcagtga
     6721 gttcgttatt cgtgtaggcc gtccgcgtgg agcgacaggt cgaggaggag catcatgaaa
     6781 ttcgaattaa ccgttgagag tagagaaggt ggaggcaaag gcccagcgcg tcaacttcgt
     6841 cgggccggcc gcgtaccggc ggttctgtat gggcagggag aatgtctcct gctgtccgtc
     6901 aagccggatg aactggtcaa agttttgcgg tcacaagccg gatccacggc actcatttcc
     6961 ctcacgatca acggggcgaa aagtaaaccc aaccgtacgg cgctgttgcg cgagtttcaa
     7021 gtcgatccga tcacgagcag cgtgttgcat gcggatttct tcgaagtcgc catggataag
     7081 ccgatccgcg tgaaggtgcc tatccatttg accggcggtc agccgatcgg cctgaaagaa
     7141 ggcggcgtgc tgcatcaggc ctt
//
LOCUS       DAOQPD010000121         7009 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_6086_length_7009_cov_23.006471, whole genome shotgun sequence.
ACCESSION   DAOQPD010000121 DAOQPD010000000
VERSION     DAOQPD010000121.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 7009)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7009)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7009
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6086_length_7009_cov_23.006471"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..966
                     /locus_tag="PK063_17660"
     CDS             <1..966
                     /locus_tag="PK063_17660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HMZ98933.1"
                     /translation="IDTPSTLLLLSAGSHPFIVQASYLPMNIKDYLEQKRLAVDRFLD
                     EVSPPAATPPTTLHESMRYSLMAGGKRVRPILTIAAAEAVGTTPPGLMAVACSLEFIH
                     TYSLIHDDLPSMDNDDFRRGKPTNHKVYGEAMAILAGDALLTMAFDLISRPELMKGCE
                     PIRQVRILQELAYGSGNMGMVGGQVFDIQAENQDIDLPTLQNIHKHKTGMLIRAAVRM
                     GAIAAGATDRQLDDMTGYAEDIGLAFQIADDVLNVTGTREELGKNPNTDAERGKKTYP
                     TFYGVEGARKLADDCVTRAIGRLNTFGSSADPLREIARYITSRKN"
     gene            1075..2058
                     /locus_tag="PK063_17665"
     CDS             1075..2058
                     /locus_tag="PK063_17665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HMZ98934.1"
                     /translation="MKALVTGATGFVGGAVARALVKAGVEVRVISRTGADLQNLAGLP
                     VEQVQGDLRDRDSLREALRGCRQLYHVAAHYALWAKDPSIFYDINVTGTRTLLETARE
                     VGIERTVYCSTIGAIGLPPGGGLGTEETPVSLEQMAGHYKRSKYLAEQEVLKLAREGL
                     PVVIVNPSAPVGEADVKPTPTGQIIVDFMKDRMPAYIETGMNLVDVDDVAQGHLLAMQ
                     KGRQGERYILGNKNLLLNEVFQILSRITGVKAPSVKLPRLAILPLAYANQWIANLTGV
                     PPRIPLEGVKMAKYKMHYDCSKAIRELGLPQTPVEVALEKAVRWFREHGYA"
     gene            2194..3003
                     /locus_tag="PK063_17670"
     CDS             2194..3003
                     /locus_tag="PK063_17670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carotenoid biosynthesis protein"
                     /protein_id="HMZ98935.1"
                     /translation="MEFFFLFLKTIWFRPYVFAFLAAFLFSAIMLIGWSRTWRFWLIS
                     WITAFVCEYSSTRNGIPFGWYHYNGSTIGQELYISNIPFMDSISFSFLLFASYCLALL
                     LLLPMAPGQRNPGFQLPRLTFALGDRTSWQVFALTVLFFAFIDMVIDPVALRGDRWFL
                     GKIYYYPNPGVHYGVPMANYAGWAVVGAISLFIYFPLDRRLATTLPAQTPSTTHRLLL
                     GAGLYYGVLIFNLAVTFWIGESLQGTTGVLMYVPVTAILLLRLLPPAPAAA"
     gene            3110..3727
                     /locus_tag="PK063_17675"
     CDS             3110..3727
                     /locus_tag="PK063_17675"
                     /inference="COORDINATES: protein motif:HMM:NF024834.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="c-type cytochrome"
                     /protein_id="HMZ98936.1"
                     /translation="MKKLCGLLLLGCLATLGILGWFGYQSYSTGFSAKAEPNELEVLL
                     ARQLRHLAIPYENRRLRNPLPVTQELMKEARAHFADHCASCHANNGSGDTVIGRNVYP
                     KSPDLRLPDTQTMSDGELFFIIQNGIRFTAMPGWGTGDPAKDSGSWQLVHFIRHLPSI
                     TEEELREMAALNPKTKQELQDEALIDQFLGGDDAAASSATGAHRH"
     gene            3751..4071
                     /locus_tag="PK063_17680"
     CDS             3751..4071
                     /locus_tag="PK063_17680"
                     /inference="COORDINATES: protein motif:HMM:NF039822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5666 domain-containing protein"
                     /protein_id="HMZ98937.1"
                     /translation="MTFLRLFIVALLLICAPAVVSAHGSGQHVLGVVSAIDATHIEIK
                     TPKGQIVSVRLTDKTQYKVRNLRRPKSPPQVGDRVVVEAEKGTDGLTATEVHYSDSQP
                     KAAQ"
     gene            4078..4551
                     /locus_tag="PK063_17685"
     CDS             4078..4551
                     /locus_tag="PK063_17685"
                     /inference="COORDINATES: protein motif:HMM:NF015953.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HMZ98938.1"
                     /translation="MRVFQLSHNQQTGPGGDGLRPLVIRALIMGLAVFLAVTIVPGIE
                     SDSLGAGVAAVLVLTLLNSLIRPLLYLLALPLIVVSLGLFMVVINALLLQLTAALVKG
                     FTVAGFGASFWGALVISLVSSILNMLLVVEQSRVEPSHRPQRPPTIINPDGSEHS"
     gene            4751..6580
                     /locus_tag="PK063_17690"
     CDS             4751..6580
                     /locus_tag="PK063_17690"
                     /inference="COORDINATES: protein motif:HMM:NF013736.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ98939.1"
                     /translation="MSPPVEPAKATAETHLQRTLTSVLNGLPADAALVAIFHQEQGPL
                     TTQVHRGFTPRDVQSIGRTLSSQKVLTAVPVGTDPEASRTMRLRLITPGAKSLLGVPL
                     RHRNRTYGFLVIGRKDNAVYAKKDKTMLEQAGDDITKALERDNLFDLNVLLSRPLVVQ
                     EPQPVIAAPDVYTPPTSHATPEIQGKIVTLLNELSQTLPFDRAWIGSYDPLAGNVEVL
                     GIAGEQKTDPKDQKKDLKAGQRLTLDASAAGWVVRHRKPRVDHDLASTQGRFLDHKHL
                     YKDRFQSSLVLPFFLRGQVGGTITLASKEADRYAVTDARLLEPINLKLVDLLQAAPPA
                     ATGAVKAEGAPDSEAGTTALTSAEPVIRKQERQAAIGEFSAFLATEIREPLGSIRAQL
                     EEVTAEGILDFDPQTRVENAMRDLIRIEAILNEILDFAKPLDLTRRLCRVPEMVENAL
                     TVVATELEATRIQVVKEYPQLLAPVRADEAKMQQVFLSIFKNAIEAMTPGGILTITMS
                     NQRAGKHLEVQILIKNNGAPIPPEHIDKVFEPFFTTKRSGTGLGLATVKKIVEEHQGS
                     IGISGAPGEGTTVTIRLPGVSRGPAHRYRGRGRRPPRRPTAAS"
BASE COUNT         1421 a         2257 c         1922 g         1409 t
ORIGIN      
        1 attgacaccc cttcaaccct tttgctactc tccgccggtt cccatccatt catcgtccag
       61 gcttcgtatc tacccatgaa cattaaagac tatctcgaac agaagcggct cgcagtggac
      121 cgttttctcg atgaggtcag tcctcccgct gccacaccgc ccacgacgct ccatgagagc
      181 atgcggtaca gcttgatggc cggcggcaag cgcgttcgac cgatcctcac catcgccgcc
      241 gccgaggcgg tcggaaccac accgccgggg ctgatggccg tggcctgttc gctggaattc
      301 atccatacct attccctgat tcacgacgat ttaccctcga tggacaacga cgactttcgc
      361 cggggcaagc cgaccaatca caaggtctac ggcgaagcga tggcgattct ggccggcgac
      421 gcactgctga ccatggcctt cgatctcatc agccggcccg aactcatgaa aggctgtgag
      481 cccatccgtc aggtgcgcat ccttcaggag ctggcttacg gatccggcaa catgggcatg
      541 gtgggcggcc aggtgttcga catccaggcc gagaatcagg acatcgatct ccccacgcta
      601 cagaatatcc ataaacataa aaccggcatg ttgatccggg ccgccgtgcg catgggcgcg
      661 attgcggccg gcgcgacgga tcggcagctc gatgacatga ccggctatgc cgaagacatc
      721 ggcttggcct ttcagatcgc cgacgatgtg ctgaatgtca ccggtacccg cgaggaactc
      781 ggcaagaatc ccaatactga tgccgagcgc gggaagaaga cctatccgac gttttatggc
      841 gtcgaaggcg cgcgcaagct ggcggacgat tgtgtgaccc gcgcaatcgg ccggctcaac
      901 acattcggct cctcagccga tccgctccgc gagatcgcgc gctatatcac ctcgcgaaag
      961 aactgacctg aggcgtgaaa cgtaagacgt gagacgcaat cccttcgatc gcgcgcccct
     1021 ctcacgtcac ccacggttca ccgttcacgc tgtccgcttc acggaaattc aggcatgaaa
     1081 gctctcgtaa ccggagcgac cgggtttgtc ggcggggccg tcgcacgcgc gctggtgaaa
     1141 gccggggtag aagtccgggt catctcccga accggtgctg atctgcagaa cctggccggg
     1201 ctcccggtcg aacaggtgca gggcgacctc cgcgatcgtg actcacttcg tgaggcgtta
     1261 cgcggctgcc ggcagctcta tcacgtggcg gcgcattacg cgctatgggc caaagatccc
     1321 tccatcttct acgatatcaa tgtcaccggc accaggacgc tgcttgagac ggcccgtgag
     1381 gtcggcatcg aacgtaccgt ctattgcagc accatcggtg cgatcggctt gccgccgggc
     1441 ggcggcttag gcactgagga gacgccggtg tccctcgaac agatggcggg gcattacaaa
     1501 cgatccaaat atctcgccga acaggaagtc ctgaaactgg cacgcgaagg cttgccggtc
     1561 gtcatcgtga accccagcgc gccggtcggg gaagcagatg taaaaccgac acccaccggc
     1621 cagatcatcg tagacttcat gaaggaccgg atgcctgcct atatcgaaac gggcatgaac
     1681 ctggtcgatg tggatgacgt ggcgcagggc catctgctcg ccatgcagaa aggccggcag
     1741 ggcgaacgct acattctcgg caataagaat ttgttactca atgaagtatt tcagattctc
     1801 agccggatta cgggcgtcaa ggcgccctca gtgaaactcc ctcgcctggc cattctgccg
     1861 ttggcctatg cgaatcaatg gatcgcgaac ctgacgggcg tgccaccccg catcccgctc
     1921 gaaggcgtga agatggccaa atacaaaatg cattacgatt gttcgaaggc cattcgcgaa
     1981 ctgggtctgc ctcaaacacc ggtcgaggtc gcgctcgaga aagcggtgcg gtggtttcgc
     2041 gagcatggct atgcttaacg gatgctgaaa aaggctttga gctgcgttct cggctcgaca
     2101 agatcctcaa cgtaccctca agggtacgcc tccggtcttg ccagcgcctg cggccttgct
     2161 aaaagacctt tttgagcatc ctccacttgc ccgatggaat tcttctttct gtttctcaaa
     2221 acgatctggt ttcgccccta cgtctttgcc tttctggcgg cgtttttgtt ttcagcgatc
     2281 atgctgatcg gctggtcgcg gacctggcga ttctggctca tcagctggat caccgcattc
     2341 gtgtgcgagt attcctcaac gcgtaacggc attcccttcg gctggtatca ctacaacggc
     2401 tcgacgatcg gacaagagct gtacatttcc aacattccat tcatggattc gatctcgttc
     2461 tcgttcctcc tgttcgccag ctactgcctc gctcttctct tgcttctgcc tatggcaccg
     2521 ggccagcgca accccggttt ccagctcccc cggttgacgt ttgcgctcgg cgaccgaacg
     2581 tcatggcaag tctttgccct gaccgtcctg ttctttgcct ttattgatat ggtgatcgat
     2641 ccggtggcgc ttcgcggcga ccgctggttt ctgggcaaga tctattatta cccgaacccc
     2701 ggcgtccatt acggcgtccc catggctaac tacgccggat gggccgttgt cggcgccatc
     2761 tccctcttca tctactttcc gctcgaccgc cgcctcgcca ccacacttcc ggcccagacg
     2821 ccttccacca cacatcgcct cttgctgggc gcaggcctct actacggcgt gttgatcttc
     2881 aacctggccg tcaccttctg gatcggcgag tcactgcagg gcacgaccgg cgtcttgatg
     2941 tatgtgccgg tgaccgccat ccttttgctc cgattactcc cccctgcacc tgcggccgca
     3001 taaatcacgc gctcctgcct gtggcaaaag gggcgcaatt ggcattcatt ggaatgagac
     3061 tgtatagtgg taaacaggcg cgatgcctgc gcgggaaggc ttgtctctga tgaaaaaact
     3121 ctgcggactg ttgttgctcg gctgcctcgc gaccctcggc attctcgggt ggttcggcta
     3181 ccaatcctac tcgaccggat ttagcgccaa ggccgaaccg aacgaattgg aagtcctgct
     3241 tgccagacaa ctgcgacacc tggccattcc ctatgagaat cgacgactcc gcaaccccct
     3301 gcccgtcacg caagagttga tgaaggaagc tcgcgcccat ttcgccgacc attgcgcttc
     3361 ctgccatgcc aacaacggca gcggggacac ggtgatcggc aggaatgtct accccaagtc
     3421 tccggatctc cgcctgccgg atacgcagac gatgtcggac ggtgagctgt tctttatcat
     3481 tcagaacggc atccggttca ccgccatgcc gggctggggc accggcgatc cggcgaagga
     3541 cagcggaagc tggcaactgg tgcatttcat ccgccacctg cccagcatca cggaggaaga
     3601 gctgcgggaa atggccgcgt tgaaccctaa aacgaagcaa gaattgcaag acgaagccct
     3661 gatcgatcag tttctgggcg gagacgatgc cgcggcatcc agtgccaccg gcgcacaccg
     3721 ccattaacgc ctcaacgaaa ggattttccc gtgacattcc ttcgcctctt cattgttgca
     3781 ctcctcctca tctgcgcccc ggctgtcgta tccgcccatg gcagtggcca gcatgtgctc
     3841 ggggtcgtct cagccatcga tgccacccat atcgaaatca agactcccaa aggccagatc
     3901 gtctcggttc gtctgacgga caagactcaa tacaaagtgc gaaatctgcg ccgcccgaaa
     3961 agtccgcctc aagtgggaga ccgggtcgtc gtcgaagcgg agaaagggac tgacggtctg
     4021 acggcgacgg aagtccatta ttccgattcc caaccgaagg cggcccaata actcaccatg
     4081 cgcgtgtttc aactctcgca caaccagcag accggacccg gcggcgacgg tcttcggccc
     4141 ttggtgatca gagctttgat catgggcctc gccgtcttcc tggccgtgac cattgtgcct
     4201 ggcatcgagt ccgacagtct cggtgccggc gtcgccgccg tgctggtact gacgctgctg
     4261 aacagcctga ttcgcccgct cctgtatctg ctggcgcttc cgctcatcgt cgtgtcgctc
     4321 gggctgttca tggttgtcat caacgccttg ttactgcaat tgacggcggc gttggtcaaa
     4381 gggttcaccg tcgccgggtt cggcgcatcg ttctggggcg ccctcgtcat cagtctggtc
     4441 agcagtattc tcaacatgct gctggtggtg gaacagagcc gggtcgagcc gagccatcgc
     4501 cctcaacgcc cgccgaccat catcaatccc gacgggtcag agcactcgtg aacgctgcga
     4561 ctttccttga gttactctga tatgactgtt acaatgcgcc ccgacgctcg atcttcaccg
     4621 cagagagcgc acaacctata acgagcatcg tgtttcgatc gtgtagcggg tctgattcac
     4681 ggtcagcgca aagacgccga tcgacaatcc ccgccccctg catcatcgga aacatcctgc
     4741 acagaggtcg atgagtcccc cagtcgaacc agcgaaagcc acagccgaaa cccatcttca
     4801 gcgcaccctg acctccgtcc tcaacggatt gccggccgat gccgcgctgg tcgcgatttt
     4861 ccaccaggaa cagggcccac tcacgacgca ggtgcaccgg ggctttacgc cgcgggacgt
     4921 tcaatcgatc ggccgcacgt tgtcgtccca gaaggtgttg acggccgtgc cggtcgggac
     4981 tgaccccgaa gcgtcgcgca ccatgcgcct tcggctgatt actcctggag ccaagtcgct
     5041 gctgggcgtg ccgctccgcc accgcaaccg cacctatggg tttctggtga tcggacgcaa
     5101 agacaatgcg gtctatgcaa aaaaagacaa gaccatgctc gagcaagccg gggacgacat
     5161 tacgaaggcc ctcgagcgcg acaacctttt cgatctgaat gtgctcctca gccgaccact
     5221 ggtggtgcag gaaccgcaac cggtcattgc cgcaccggat gtctacactc cgccgacttc
     5281 ccacgcgacg ccggagatcc agggcaagat cgtcaccctg ctcaatgagt tgagccagac
     5341 cctgccgttc gatcgcgcct ggatcggttc ctatgatccg ctcgccggca acgtcgaagt
     5401 actgggcatc gccggggaac aaaagaccga tcccaaagac cagaaaaagg atctcaaagc
     5461 tggccagcga ctgacgctcg atgcctccgc tgccggctgg gtggtgcgtc accggaagcc
     5521 ccgggtcgac catgacctcg cttccacgca aggccgcttt ctcgatcaca agcatttgta
     5581 taaagaccgc ttccaatctt cattggtatt gcccttcttc ttgcgcggcc aagtcggtgg
     5641 aaccatcacg ctggcctcga aggaagcaga ccgctatgcg gtgaccgatg ctcgcttgct
     5701 cgagccgatc aacctcaaat tggtggattt gctccaggct gcgcccccgg cggcaaccgg
     5761 cgccgtcaaa gccgaaggcg cgccggattc cgaggccggg accacagcat tgacctccgc
     5821 cgagccggtc atcagaaagc aggagcggca ggctgctatc ggggaattca gcgcgtttct
     5881 ggccactgaa atccgtgagc cattgggctc gatccgcgcg cagttggaag aagtcacggc
     5941 ggaaggcatt ctcgatttcg acccgcagac ccgtgtcgag aacgcgatgc gcgacctgat
     6001 ccgcatcgaa gcgatcttga atgaaatcct cgatttcgcc aaaccgctgg acctcacgcg
     6061 ccgcctctgt cgcgtccccg aaatggtgga aaacgcgtta accgtggtgg ccaccgaact
     6121 ggaagccacc cgcattcaag tcgtcaaaga atatccccag ctcctcgcgc cggtgcgcgc
     6181 cgatgaagcg aagatgcagc aggtcttcct cagcattttc aaaaatgcga tcgaggccat
     6241 gaccccgggc ggcatcctga cgatcaccat gagtaaccag cgggccggca aacatctgga
     6301 agtccagatc ctgatcaaga ataacggggc accgatcccg cccgaacata tcgacaaggt
     6361 tttcgagccg ttctttacga cgaagcgttc cggcaccggc ctcggtctcg ccacggtcaa
     6421 gaagatcgtc gaggagcatc agggcagcat cggcatttcc ggcgcaccag gcgaaggcac
     6481 aaccgtgacg attcgcctgc ccggcgtcag ccgtgggcct gcgcaccgct atcgtggccg
     6541 cggacgacgc ccgccgcgtc gccccaccgc cgcatcgtag ctgctgacct ccaaggattc
     6601 gatccgaagg ttagacctga agcgaatctt ttcagtgcgc ctacgcctga catcaaacaa
     6661 cacaatattc tcgttccaga cgcgtgcacg ccggcctggc atgccatcac cccagccgcc
     6721 tatggacagg cggggtgagc ctcctcctgc gcacgtccaa cgagggcctt ctgaggccgc
     6781 gctcatcttc aacaatcacc gcacacacct gcgggtggtc atggaggccg tccaactgcg
     6841 cgcatgggcc gagcacattc cgattgtgcg cggtctgcga gcaactggat ggcctcagaa
     6901 ccacccgttc ccctcccccc tttattcttg acacggcttc ttcaggaagc taagattccg
     6961 gcactcttaa ggcttttaac gtctatatac tcgaccacca tactttcac
//
LOCUS       DAOQPD010000122         6628 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_6633_length_6628_cov_24.736346, whole genome shotgun sequence.
ACCESSION   DAOQPD010000122 DAOQPD010000000
VERSION     DAOQPD010000122.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 6628)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 6628)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6628
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6633_length_6628_cov_24.736346"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            50..2281
                     /locus_tag="PK063_17695"
     CDS             50..2281
                     /locus_tag="PK063_17695"
                     /EC_number="2.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003825 - alpha,alpha-trehalose-phosphate
                     synthase (UDP-forming) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose-6-phosphate synthase"
                     /protein_id="HMZ98940.1"
                     /translation="MRLSLRFILPLLLVLGVVAYSVVPLVDSLTLKWFTRDLESRSKL
                     LASTMEVPLADLVVSRSRTKIFAYFHKVIQDERLYALGFCDTQQRLLYQTLTYPDQLS
                     CESLAHLAPGSSEVVDFAQGPLHVVVATIQSGGKVQGRLMLVHDMSFVHQRSTDTKWY
                     IFYLFVGLAGVISAVTVLVAQLSWRGWVAGVRAMLTSKGLPAESSQAHSAELHPVAQD
                     LHALVRELEADRRMRDESQITWSPASLKTILHEHLSGDEILIVSNRQPYIHNRRGQKV
                     EVQVPASGLVSALEPVMRACSGVWIAHGNGSADKEVVDNRDHVRVPPDHPSYDIRRIW
                     LSPDEESGFYYGFSNEGLWPLCHNAHVRPTFRTSDWEQYVAVNERFAKAVVEEAKTDD
                     PVILVQDYHFALLPKMVREKLPNATIIMFWHIPWPNSESYGICPWRQEILEGLLGSSI
                     VGFHTREHGNHFLSCIDRILEARIDRDSSTVSYGGRLTAVNPYPISIEWPSRWLENQR
                     PVPDCRVHIRERHAMGPDRLVGIGVDRLDYTKGIIERFLAVERLFELQPEWVGKFSFI
                     QIAAPSRTIIDQYQHFHDQVYALAERINKRFGREGYEPIVLKVKHHEPPDVYEYYRAS
                     DLCFVTSLHDGMNLVAKEFIAARDDEQGVLILSQFTGAAQELPEALVVNPYDIDQCAA
                     ALHMALSMTPKEQRARMRSMRGLIQEFNVYRWAGRMLMDAARMRRRIRVMKQVGQASG
                     RGR"
     gene            2299..>2987
                     /gene="otsB"
                     /locus_tag="PK063_17700"
     CDS             2299..>2987
                     /gene="otsB"
                     /locus_tag="PK063_17700"
                     /EC_number="3.1.3.12"
                     /inference="COORDINATES: protein motif:HMM:TIGR00685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004805 - trehalose-phosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose-phosphatase"
                     /protein_id="HMZ98941.1"
                     /translation="MFSAQGKRVLDRLASQGGSLFAFDFDGTLARIVQDRHAAGLTES
                     TREALQGLAEVAPTAIISGRSLADLAPRVKGIAAHLIGNHGLEGLHASERVMQQAQDC
                     CSAWLKAVTKDALDLTRAGVVVEDKMYSLTFHYRQAWSPAAARETIFHVVSTLLPAPR
                     LVLGKAVVNAIPSGNLHKGTAMLELMHQLQISAALYVGDDDTDEDVFSLPDERIVSVR
                     VGKKAATAAQW"
     assembly_gap    2988..3087
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(3245..3730)
                     /locus_tag="PK063_17705"
     CDS             complement(3245..3730)
                     /locus_tag="PK063_17705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macro domain-containing protein"
                     /protein_id="HMZ98942.1"
                     /translation="MLKEVSGDILLSTAGAIAHGIAPHDNFKQGLALALREQWPGMYK
                     DFRHYCQTYNPKPGGAWSWKGPNSPVIINLFTQEPPATEQDHPGKATLPNVNHALQAL
                     KKELQEHQVKSLALPRLATGVGGLEWEKVYPLLQQALKELHIPVYVYGLYKKGVAAQE
                     A"
     gene            3885..>4693
                     /locus_tag="PK063_17710"
     CDS             3885..>4693
                     /locus_tag="PK063_17710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate kinase 2 family protein"
                     /protein_id="HMZ98943.1"
                     /translation="MERYRIKPGCRPSLKRFDPDDTGSYKKNAAGKAKAKTAAAKHIA
                     TLDQLQERLYANRTRALLIILQGMDTSGKDGTIKHVMSGVNPQGCHVASFKAPSEKEL
                     EQDFLWRIHQEVPAKGYIGIFNRSQYEDVLITRVHGLVSKKIVTQRFNQINEFEELLV
                     ENGTVIIKLFLHISKEEQKARLTERICDPEKRWKFSEGDLEERKLWDDYMTAFEDLMA
                     ATSTERAPWYIVPANRKWYRNLVVAELVMQALAAMKLSTPPAPKGVNFDGLT"
     assembly_gap    4694..4793
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <4794..5525
                     /locus_tag="PK063_17715"
     CDS             <4794..5525
                     /locus_tag="PK063_17715"
                     /inference="COORDINATES: protein motif:HMM:NF025729.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4412 domain-containing protein"
                     /protein_id="HMZ98944.1"
                     /translation="GDRGRVETIREDGQAHVMLFNGKTRTMQMGMPGQKSYMEISLEG
                     DRGEHLNELLEAQHVERTGKTEKIAGYTCEVWRITDKEQHRPKSELCVAKGFGKAATF
                     WIDPKEARRSSQPGWVKQLAEEGGFGLRSIQYDEAGKESGRMEVVSIEKKTLDASLFA
                     FPADWAKHDLSGFQERMKAMREQKREGGADVSKMVEEMKKRKAARGKPGEAPGGEEQP
                     PDMKELMKQFGEAMKKQQSQPQGGQ"
BASE COUNT         1372 a         1740 c         1970 g         1346 t
ORIGIN      
        1 ccccagacca taagagattt tgctctcaaa gtaaactgcg ggagaaaaaa tgcgattgtc
       61 cctccggttt atccttcccc ttttgctggt gcttggtgtc gtcgcgtaca gcgtggtgcc
      121 cttagttgat tcccttacat tgaagtggtt cacgcgtgac ctggaaagcc ggtcgaagtt
      181 gttggccagc accatggaag tgccactggc ggacctcgtc gtctcccgct cccggacgaa
      241 gattttcgcc tacttccata aggtgattca ggatgaacgg ttgtatgcgc tgggcttctg
      301 cgatacccag cagcgtctgc tctaccagac cctgacctac ccggatcaat tgtcctgcga
      361 aagcttagcg cacctggcgc ccggttcttc tgaagtcgtg gactttgccc aagggccgct
      421 gcacgtggtc gtcgcgacga ttcaatcggg cggcaaggtg cagggccggt tgatgctggt
      481 ccatgacatg agttttgtgc accagcgcag caccgacacc aagtggtaca tcttttattt
      541 gttcgtcggc ctcgcggggg tgatttcggc cgtcaccgtg ctggtggcgc aactgagttg
      601 gcgcggatgg gtggccgggg tgcgggcgat gttgaccagc aaagggctgc cggcggaatc
      661 cagccaggcc cattccgcgg agttgcaccc ggttgcgcag gatctccatg cgttggtgag
      721 ggaactggaa gccgatcgcc gtatgcggga tgaaagtcag attacctgga gcccggccag
      781 cctcaagacg attctccatg agcatctgtc gggtgatgaa attctcatcg tgtcgaatcg
      841 acagccgtac atccataacc ggcgcggaca gaaagtcgaa gtccaggtgc cggccagtgg
      901 actggtctca gccctcgagc cggtgatgcg agcctgctcg ggcgtgtgga ttgctcacgg
      961 caatggatcg gccgacaaag aagtggtgga taatcgggat catgttcgcg tgccgccgga
     1021 tcatccctcg tacgatattc gtcggatttg gctgtcgccg gatgaagagt ccggctttta
     1081 ctatggtttc tccaacgagg ggctttggcc gctgtgccat aatgcgcatg tgcggcctac
     1141 gttcaggact tctgactggg agcaatatgt cgcggtcaac gaacggttcg caaaggccgt
     1201 ggtcgaagag gccaagaccg atgatcccgt catcctggtg caggactatc actttgcgtt
     1261 attgcccaag atggtacggg agaagttgcc gaacgccacg atcatcatgt tctggcatat
     1321 tccctggccc aactccgaga gttacggcat ttgcccctgg cgacaggaaa ttttggaggg
     1381 attactgggc agcagcatcg tcgggtttca tacccgcgag cacgggaacc atttcctgtc
     1441 ctgtatcgat cgcattttag aggcacgcat cgatcgcgac tcgtccaccg tgtcgtatgg
     1501 tgggcggctg acagcggtga acccctaccc catttccatt gagtggccgt cgcgctggct
     1561 ggaaaaccaa cgccccgttc ccgactgtcg ggtgcacatt cgtgagcgac atgccatggg
     1621 gcctgatcgg ctggtcggca tcggtgtcga ccgcttggat tacacgaagg gcatcatcga
     1681 acgatttctc gcggtcgaac ggttgtttga actgcagccg gaatgggtcg gcaagttttc
     1741 gttcattcag attgcggcgc cgagccggac gatcatcgat cagtatcaac attttcacga
     1801 tcaggtctat gccctcgcgg aacgcatcaa caaacggttt ggccgtgaag ggtatgagcc
     1861 gatcgtgctg aaggtgaagc atcacgagcc gccggatgtg tatgagtact atcgcgcgtc
     1921 cgacctgtgc ttcgtgacca gtttgcatga cggcatgaac ctggtggcca aagaattcat
     1981 cgccgctcgt gacgacgaac agggcgtcct catcctcagc cagtttaccg gcgccgccca
     2041 ggagttgccc gaagcgctgg tggtcaatcc ctacgacatc gaccaatgcg ctgcggcctt
     2101 gcacatggca ctgtcgatga cgccgaaaga acagcgtgca cgtatgcgga gcatgcgcgg
     2161 gttgattcag gaatttaatg tctatcgatg ggcgggccgc atgctcatgg atgcggccag
     2221 aatgcgccgt cgcattcgcg tcatgaagca ggtggggcag gcctcggggc gggggcgata
     2281 gtcacgccga tgcaggacgt gttcagtgct caaggcaaac gtgtgctcga ccggctggcc
     2341 agccagggcg gctcgctttt tgcctttgat ttcgacggca cgctggcgcg catcgttcag
     2401 gatcggcatg ccgcaggtct gaccgaatcg acgcgtgaag ccttgcaagg tctggccgag
     2461 gtcgcgccga ccgcgatcat ttccggacgt tccctggcgg acctcgctcc ccgtgtgaag
     2521 ggcattgctg cccatctcat cggcaatcat ggactggagg ggttgcacgc gtcggagcgt
     2581 gtcatgcagc aggcgcagga ctgttgcagc gcatggttga aggccgtgac caaggatgcc
     2641 cttgacctga cgcgagccgg cgtcgtggtg gaagataaga tgtactccct gacctttcac
     2701 tatcgtcagg catggtcgcc agccgccgcc cgtgaaacca tttttcatgt cgtgtccacg
     2761 cttcttcctg cgccccgact ggtcttggga aaagcggtgg tcaacgctat tccctcgggc
     2821 aatctgcaca aggggacagc catgctggag ttgatgcatc agctccagat atccgccgcg
     2881 ctttatgtcg gagacgacga tacggatgag gatgtgtttt cgctgccgga cgagcgcatt
     2941 gtctcggtgc gtgtggggaa gaaggcggcg accgccgcgc aatggtannn nnnnnnnnnn
     3001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3061 nnnnnnnnnn nnnnnnnnnn nnnnnnnctc cgagactcac cgtacggcag gagtacgatt
     3121 cgcctctttg ttcgcgacgg ccttgctgga cgatcttttg cgcatcctgc gggaggtgcc
     3181 gacgccagca aggcacttgg gttgctcatg tgctctcatg caaaaacggt tgtgccgtag
     3241 gccgctaggc ttcttgcgcg gcgacccctt tcttgtacag tccatacacg tagacgggaa
     3301 tgtggagctc tttcagggcc tgctggagca agggatacac cttttcccat tccaaccccc
     3361 ccactcccgt ggccagacga gggagcgcca ggctcttcac ctgatgctcc tgcagttcct
     3421 ttttcagcgc ctgcagcgca tgattgacgt tggggagtgt cgccttgcca ggatgatcct
     3481 gttcggtggc cggcggctcc tgcgtaaata aattgatgat gacgggagag ttcgggcctt
     3541 tccacgacca ggcgccgccc ggtttgggat tgtaggtctg gcagtaatgg cgaaaatctt
     3601 tgtacatgcc cggccactgc tcgcgaagtg ccaacgccaa accctgcttg aaattgtcgt
     3661 ggggagcgat accatgcgcg atcgcgccgg cggtggataa cagaatgtct ccgcttactt
     3721 ccttgagcat gaccgatgcc tccttgattg agtaaaagat ctgtttatca cataagactg
     3781 tgccctcttc aatcaatgga ttcatagaaa taaatttttc cacgctataa gggcgactac
     3841 tttgatcgcc gaccacagga cgctgccata gcaggaggaa cgacatggag aggtatcgaa
     3901 tcaagcccgg ttgccgtcca tcactcaaac ggtttgatcc tgacgatacc gggtcgtaca
     3961 aaaagaacgc ggctgggaag gccaaggcca aaaccgccgc ggccaaacac attgccacgc
     4021 tcgatcaact gcaggaacgg ctgtacgcca accgcacacg ggcgttgctg atcattctgc
     4081 aaggcatgga tacgagcgga aaggacggca cgatcaagca tgtcatgtcc ggtgtgaacc
     4141 cgcagggctg tcacgtggct tcctttaaag cgccgagcga gaaagagctc gagcaggatt
     4201 ttttgtggcg gattcatcaa gaagtgccag ccaagggcta cattggcatt tttaaccggt
     4261 cgcagtatga agacgtgttg atcacgcgtg tgcatggtct ggtgtcgaag aagatcgtca
     4321 cgcagcgatt taatcagatc aatgagttcg aagagctact ggtcgagaac ggcacggtga
     4381 tcatcaagct gttcctgcac atttccaaag aggagcagaa agcgcgtctc accgaacgca
     4441 tctgtgatcc cgagaagcgc tggaaattca gcgagggaga tttggaagag cggaagctgt
     4501 gggacgacta catgacagca tttgaagacc tcatggcggc gaccagcacc gagcgggctc
     4561 cctggtacat cgtgcctgca aatcggaaat ggtatcggaa tctggtcgtc gccgagctcg
     4621 tgatgcaggc gcttgccgcg atgaaacttt ccacgcctcc ggcccccaaa ggcgtgaact
     4681 tcgatgggct cacnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnggcgata
     4801 gggggcgtgt ggaaacgatc agggaggatg gccaggccca tgtcatgctg tttaatggca
     4861 agaccaggac gatgcagatg ggcatgccgg ggcagaagtc ttatatggag atcagcctgg
     4921 agggagatcg gggtgaacat ctgaacgaat tgctcgaagc gcaacatgtc gagcgcaccg
     4981 gcaagaccga gaagatcgcc ggatatacct gcgaggtgtg gcgcattacc gacaaggaac
     5041 aacatcgccc gaagagtgag ctctgtgtgg caaaaggttt cggaaaggcc gcgacgtttt
     5101 ggatcgaccc caaggaggcc cggcggtcct ctcagcctgg ctgggtgaag cagttggctg
     5161 aagaaggagg gttcgggctt cggagtatcc agtacgatga agcgggcaag gaatccggcc
     5221 gcatggaagt ggtcagtatt gagaagaaaa ccttggacgc gagcttattt gcgtttcccg
     5281 ccgactgggc caagcacgac ctctccggct ttcaagaacg gatgaaggcc atgcgggagc
     5341 agaaaagaga aggcggggca gacgtctcga agatggtcga ggagatgaag aagcgaaagg
     5401 ctgcacgtgg gaaacccggc gaagctcctg gcggcgagga gcagcctccg gatatgaaag
     5461 agctgatgaa gcaattcggc gaagcgatga agaaacagca gtcgcaaccg cagggcgggc
     5521 aataagcggc atgcctgggt cgaaaagagt ggcacatcaa atcgcacagc gaggtgaatc
     5581 cgatccgtct atggccggct caggaattcg gcgtgagctc cgatggcggt ggacctggga
     5641 attccccttg ttgacaagtt tttttgaggg gcgtagatag gggctgcggc ccatttcgct
     5701 tgtcgcaagt ggaagaccgg acagaccgcg cggctgccat ctagatcttc cacacattcc
     5761 cgcaacagaa gggagggtag acgatgaccg atacctctcc acctggcctg tacggcctgc
     5821 cgaactgaag gcaggtttct cgtcggtttt ttttgccaac cggttctcat cgcaaatgcc
     5881 acaaggcatt ccacgacgcg ctcatgcgcg tcccggcgtc atgccaccga atggagggcg
     5941 aggttgacga tctttgacgc ggtcatcagg ccggccgtga tcgcgagctc atcggcgaga
     6001 tggcttctgc tattgatcaa ctcggcgggt cttctacggg ccgctacata gacagagcga
     6061 tcggcgtcct aagcgccaca cacgggctcc cgtcacacac gggagcccgt gttgtatcgg
     6121 gactctcccg gccaccggga acatgaggaa aaatgactag ggccgatttt cctgttgaca
     6181 gagttttcta acgagcgtaa gagggaaatt gtaagcttca agggccgtgt taaccgtgac
     6241 gaggcgatgg acagtgcgcg cctgttcggg agacctcgcc actcctcaac cggggaggtc
     6301 cacgcatgga agaacttacg ccgccggact aaaacggccc gccgagttga gggcgggctg
     6361 atcgtcggtc gtgcagaccg atccttccct ggcttgtgtc tgatggcact atccgtttaa
     6421 ggataacagc cagcgcaaag atgaaggatt gaagccaagc acgaggcaca ccagaatcct
     6481 gggaacatgc ttcccccgac gaacatcctg atcatccatc ttctcgaacg ggtctggtct
     6541 gtcggacaac ctatttgact gtaggcgtcc caagcgccaa ccacgggcga cctcccaccg
     6601 cagtgtaggg tcgcccgtgg cattttaa
//
LOCUS       DAOQPD010000123         6620 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_6641_length_6620_cov_20.239147, whole genome shotgun sequence.
ACCESSION   DAOQPD010000123 DAOQPD010000000
VERSION     DAOQPD010000123.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 6620)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 6620)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6620
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6641_length_6620_cov_20.239147"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1452)
                     /locus_tag="PK063_17720"
     CDS             complement(<1..1452)
                     /locus_tag="PK063_17720"
                     /inference="COORDINATES: protein motif:HMM:NF012975.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - ribonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNB domain-containing ribonuclease"
                     /protein_id="HMZ98945.1"
                     /translation="MPNHRIDLKRLARHAMIDRGLWPDFSAKAMAELAQIRAAAVDHG
                     ADAQDLRDLLWVSIDNDDSLDLDQITVATEHPDHSVTLLVAIADVDALVPKDSAIDTH
                     ARHNTTSVYTSGDIFPMLPEPLSHDLTSLREHQDRLAVVVDLAIAANGKVSGASHYRA
                     LVRNHAKLAYNSVAAWLTGTGPAPDSISDVPGLDAQLRLQDRVAQQLKARRHQQGALS
                     LETIEPRAVFDGDTLTGITVEQKNRAKELIEDCMIAANQATASYLKRKGIPSFRRILR
                     SPERWQRIVDVAASCGESLPPQPDAQALDAFLVKRRAADPIRFPDLSLAIVKLIGRGE
                     YVLDEGTGGAPEHFGLAVKGYTHSTAPNRRYPDLVTQRLLKAALAGAPLPYRTDELKY
                     LADYCTEKEDDAERVERQMRKSAAALLLQPRIGERFEAIVTGLSEKGTWVRLLEPPVE
                     GKLSGGVMGLDVGDRLTVELVSTNVERGFIDFSR"
     gene            complement(1621..1806)
                     /locus_tag="PK063_17725"
     CDS             complement(1621..1806)
                     /locus_tag="PK063_17725"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98946.1"
                     /translation="MRFVKVKDEERPGEVAINLDLVREAHFGGGLLHLYFERSSSAQD
                     DMTFTGENAQKIWAAMG"
     gene            complement(1951..2232)
                     /locus_tag="PK063_17730"
     CDS             complement(1951..2232)
                     /locus_tag="PK063_17730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HMZ98947.1"
                     /translation="MPYVLIIHEVDAYPAWKSIFDQAAQIRKQAGEIRYQLLQHDTNP
                     NRLVHFSEWTSLDKARSFFESPELVEIRRKAGVKAPAFHYLNEVEQGRL"
     gene            2427..2705
                     /locus_tag="PK063_17735"
     CDS             2427..2705
                     /locus_tag="PK063_17735"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98948.1"
                     /translation="MANLFARHPHTVKDMIVAETLCPLHQEPVKVGFEMNGVQGKLTV
                     REHCSILQMGEKCSEACRSNPEILEAVHKKMAEFKEESAREIPIISTP"
     assembly_gap    2859..2958
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            3201..3962
                     /locus_tag="PK063_17740"
     CDS             3201..3962
                     /locus_tag="PK063_17740"
                     /inference="COORDINATES: protein motif:HMM:NF018755.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1353 domain-containing protein"
                     /protein_id="HMZ98949.1"
                     /translation="MPDPVQMQFSQANAYLTELISQFAGIEKRIEGGETVTLNLSDQG
                     RTLSLVVSREHVTESAPPAKSPTGGVSSMLADNHSLVAALTKTFVFDLGQANRNISAA
                     DVQRHFTHATRQTRRDEADLIPNVPDPVVKHDGHLWVVAEDCRYVALDGCIITAKRGF
                     KSDLASIPRLFWAVIASFELSLVAPIMHDLIYRCGGQVILPDGEVIPAGKLFSRKDAD
                     DVFLELMTRSKVAYWKRNVAYLAVRAFGQSSWQGR"
     gene            complement(4035..5234)
                     /locus_tag="PK063_17745"
     CDS             complement(4035..5234)
                     /locus_tag="PK063_17745"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF025025.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HMZ98950.1"
                     /translation="MSVIIPTYNRAPLLKTAITSALHQERAGDLFDVEVIVVDDCSPE
                     DMSPIVSEFPGVRYIRLPENRGASGARNAGIKEASGKYVALLDDDDEFLTHKLMIQVP
                     VLEADPDVGVVYGQSVVTGSDTPLLLWPEWGPSGRVFEEFLTRTEDFLHPPTWLVRRE
                     LFEAAGWFNEQHRTMEHYDMALRLSMLTSWTFLSGGPVARGRFSKKGKWYSNIVNGTN
                     EERLPRIVESALARLPATPEAERTRRKARAAVCATIAGQRWWTGGGLEPTKQHLLASL
                     RTSAWLLHEAPVMEWIQRIAGTVAGGSHQPVQAVRAFWEEIKQATSAAPDAHTIPMRG
                     VLGDMLSSAAITMKQGSPRRAWMVGLGSIVHNPKSLKQPARLLHLYRALATTPATSGT
                     RLPISPS"
     gene            5685..6155
                     /locus_tag="PK063_17750"
     CDS             5685..6155
                     /locus_tag="PK063_17750"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98951.1"
                     /translation="MPGFLPLLKAHDDSRCLAESQFREGLRRERRTISTLTLKVQGLC
                     HLGRARGSDMFPNLKFKNATGNINGTRHMTRGIFLWFAYINDESVARIISHFPISFHS
                     NRVDVLLRGLNLLHEGGGKGLRKSRSWNRQQATGESDECQNDQWVHDMLLFIVN"
BASE COUNT         1331 a         1792 c         1972 g         1425 t
ORIGIN      
        1 tcgcgagaag tcgatgaaac cccgttcgac attcgtgctc accagttcga cggtcagacg
       61 atcgccgaca tccaacccca tcacgcctcc ggacagcttt ccttcgaccg ggggctcaag
      121 cagccgcacc catgttccct tctcggacag gccggtgaca atggcctcga atcgttcgcc
      181 gatacgaggc tgcaagagca gggcggccgc ggattttctc atttgccgtt ccacccgttc
      241 cgcatcatct tccttctcgg tgcaatagtc ggccaaatat ttcagttcat ccgtccggta
      301 gggcaggggc gcgcccgcca gggctgcttt gagcaatcgt tgggtcacga gatcgggata
      361 ccgccggttc ggcgccgtgg aatgcgtata ccctttcacg gctagtccga aatgttccgg
      421 cgcgccgccc gttccctcat cgagcacata ttcgcctcga ccgatcagtt tcacgatggc
      481 cagtgagagg tcgggaaacc ggatcgggtc ggccgctcgc cgtttgacga ggaaggcatc
      541 caatgcctgc gcatcaggct gcggaggcaa ggactcgcca caacttgcgg ccacgtcgac
      601 gatccgctgc cagcgttccg gggagcgaag gatgcgccgg aaggagggga tgcctttgcg
      661 tttgagatag gaagcggtcg cctggttggc ggcgatcata caatcttcga tcagctcctt
      721 cgcacgattt ttctgttcga ccgtgatgcc ggtcagagta tcgccgtcaa agacggcgcg
      781 tggctcgatg gtttcgagac tcagcgcacc ctgctggtgt cgtcgtgctt tgagctgttg
      841 cgccacgcga tcctgaaggc gcagttgcgc gtcgaggccc ggcacgtcgc tgatgctatc
      901 gggtgccggt cctgttcccg tcagccaggc ggcgacactg ttgtaggcaa gtttggcgtg
      961 attgcgaacc aacgcccgat aatgagacgc cccgctcact tttccattcg cggcgatggc
     1021 gaggtctacc acaacagcca gccggtcctg atgttcgcgg agcgaggtca gatcgtgaga
     1081 aagcggctca ggcagcatgg ggaaaatatc gcccgacgtg tagaccgagg tggtgttgtg
     1141 gcgcgcgtgg gtatcgatag cggaatcttt gggtacgagc gcatcgacgt cggcaatcgc
     1201 caccagcagg gtgactgagt gatctggatg ttcggtggcc accgtaattt gatccaggtc
     1261 gagcgagtca tcgttgtcga tggagaccca cagcaggtcc cggaggtctt gcgcgtccgc
     1321 tccatggtcg accgctgccg cgcggatctg ggccagctca gccatggctt tggcggagaa
     1381 gtctggccac aagccgcgat caatcatcgc gtgtcgggca agacgtttga ggtcgatacg
     1441 atgattcggc atgaggtcct cgagttgatg tgccaacagc aagccgtcga ggcgaatggc
     1501 ctccgtatga ctagctataa cacgaatcga gcagagcgtg ggcgtgagtc acagcctgcg
     1561 acagagggag gatgcaagga aaagggaatg ctggagaggt cgaggaatag ggccgtctcg
     1621 tcaccccatc gcggcccaga ttttttgggc gttctcgccg gtaaaggtca tgtcatcctg
     1681 cgccgaggaa ctgcgctcga agtacaggtg cagcaagccg cctccgaaat gcgcttctcg
     1741 caccaggtca agattgatgg caacttcacc gggccgttcc tcgtctttta cttttacgaa
     1801 tcgcatgatg acctcgttgt tggttgatgg cgctatcggt attcgcacag cgtgtgaagg
     1861 gtcagcatat cccagactga tgaaaagcgt gagcaaaggt cggaaatgtg tgtgaatacc
     1921 aggccgtcga ggcgactcag gtcgcggcat tcacaaccgg ccctgctcga cctcattcaa
     1981 atagtggaat gccggcgcct tgactcccgc tttgcgccga atctcgacca gctccggaga
     2041 ctcaaaaaag ctgcgggcct tgtcgagcga cgtccattct gagaaatgca cgagccggtt
     2101 gggattggtg tcatgttgca ggagctggta tctgatctca ccggcttgtt ttctgatctg
     2161 tgccgcctga tcgaaaatcg acttccacgc cggataggcg tccacttcat gaatgatcaa
     2221 cacgtaaggc atgagtctcc tcggttgtga cagccactga aggaaagtgt gattgcgtcc
     2281 agtctaatac agtgggggtc ggggatgcag ccgtggcgtg ggtacgctgc aaatgcgata
     2341 caagtttgtg ccggaggggt ctcttgatac agtgatgtgg gaggccactg taccactatt
     2401 cacccgtcac acagtaagga gtccatatgg cgaacctatt tgcaaggcat ccacatacag
     2461 tcaaggacat gattgtggcc gagaccctct gtccgctgca tcaggagccg gtgaaggtcg
     2521 gcttcgagat gaatggcgtg caggggaagt taacggtccg ggagcattgt tcgattctgc
     2581 agatgggcga aaagtgcagt gaagcctgcc gcagcaatcc tgaaatcctt gaggccgttc
     2641 acaagaagat ggcagagttt aaggaagaat ccgcgcgaga aattccgatt atttccactc
     2701 cctagtcccc tgtcggagtg acctgttctg gtggccctcg cgaactgtgg ccccagagag
     2761 ctttcagccg ccttcgcctg tgatgcgggg gcggcggttt ctccacctac cgccgcagtg
     2821 acgctcctct aggattcatt tcctgacatc tcatttcann nnnnnnnnnn nnnnnnnnnn
     2881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2941 nnnnnnnnnn nnnnnnnnca cctaccgccg cagtgacgct cctctaggat tcatttcctg
     3001 acatctcatt tcacgccttt cgcgtgtttc gtggcgcgcg atatctgttc gcttgcagat
     3061 gcctttcgat gtgtcagctg gatacccttt cctcacagaa attggccact tcgtgtgagg
     3121 ggaaggcttg aggaaggtct atcggtttag gcatgatgcc gcagtcgatg tgacggatgc
     3181 accaaaccga ggagacaggt atgcccgatc cggtacagat gcagttctcg caagcgaatg
     3241 cctatctcac tgagcttata agtcagtttg cgggtatcga gaagcgaatc gaaggaggcg
     3301 agaccgtgac cttgaacttg agtgaccagg gacgcaccct gtcgcttgta gtcagccgtg
     3361 agcatgtcac cgagagcgcc ccgccagcca agtctccaac gggaggtgtc tcctccatgc
     3421 ttgccgacaa ccatagcctt gttgccgcgc tgaccaaaac gtttgtcttt gatctcgggc
     3481 aggccaatag gaatatttct gctgccgatg tgcagcgtca ctttacacat gccacgcgac
     3541 aaaccaggag ggatgaagct gatctgatac ccaacgttcc tgatccggtt gtgaaacatg
     3601 atgggcacct gtgggtcgtg gcggaagatt gccggtatgt tgcgctcgat gggtgtatca
     3661 ttacggccaa gcgcggcttt aagagcgact tagccagtat cccgcgtctt ttttgggcgg
     3721 tcattgcgtc atttgagctc tcgctggtcg ctccgatcat gcatgatttg atctatcgct
     3781 gcggaggaca ggtgattctt ccggacggcg aggtgatccc tgccggcaag ctgttcagtc
     3841 ggaaagatgc cgatgacgtg ttcctggaat tgatgaccag atccaaggtc gcctattgga
     3901 aacgtaatgt ggcgtatctt gcggtgcgag catttggcca gtcatcctgg caagggagat
     3961 gaggtgaggc gggttttggt agggtctgca gtcggctctc ccgacggagg ccggcgaaac
     4021 aacgacctct caccttacga gggagaaatc ggaagtcgag tccccgatgt cgcgggagtc
     4081 gtggccagtg cgcgatacaa gtggagcagc cgtgccggtt gtttcagcga cttgggatta
     4141 tggacgatgg agccgagtcc caccatccat gctcgccgtg gtgacccttg tttcatggtg
     4201 atggccgcgc tcgagagcat gtctcccaac actccccgca tgggaatggt gtgagcgtcc
     4261 ggggcggcgg aggtggcttg tttgatttct tcccagaagg ctcgcaccgc ctgcaccggc
     4321 tgatgcgacc ctccggccac tgtgcccgcg atccgttgaa tccactccat caccggtgct
     4381 tcatgcagca gccacgctga ggtgcggagc gacgccagca gatgctgctt ggtcggttca
     4441 agcccgccgc ccgtccacca tcgttggccg gcaatcgtgg cacagaccgc ggcgcgagct
     4501 ttgcggcgag tgcgttcggc ttcaggagtc gcgggtaatc gagccagggc gctctccaca
     4561 attcgcggga gccgttcctc gttggtgccg ttgacgatat tgctgtacca ctttcccttc
     4621 ttggaaaagc gaccacgcgc gaccggcccg ccgctgagaa atgtccagga ggtcagcatc
     4681 gacaggcgga gcgccatgtc gtaatgttcc atggttcgat gttgttcatt gaaccatcct
     4741 gccgcttcga atagctcccg tcgcacgagc caggtgggag ggtgaagaaa gtcttccgtc
     4801 cgcgtcagaa actcttcgaa cacccggcct gacggtcccc attccggcca caggagcagg
     4861 ggcgtatcgc tgcccgtgac gacactttga ccatagacga cgcccacgtc cggatcggcc
     4921 tccaggaccg gcacctggat catgagttta tgggtgagga attcgtcgtc atcatccaag
     4981 agggcgacat acttgccact ggcctctttg atgccggcat ttctggcacc cgatgccccg
     5041 cgattttcag gcaagcggat ataccgcacg cctggaaact cgctcacgat cgggctcatg
     5101 tcttccggtg agcagtcatc gaccacgatg acttccacat caaacagatc gccggctcgc
     5161 tcctggtgta atgcggaggt gatcgctgtc ttgagtagcg gtgcccgatt gtacgttgga
     5221 atgatgacac tcacgagcgg gcgtccggat gatcgcgtgg ccgccagtcg agacgctgtg
     5281 gggggctgag gtatcggcat gaattttgtc aaacaatcac tacagcggaa tgagaagaaa
     5341 cggctatggc ctgctgccta cccggcttgg atcggctcag catgaaaaca gcccgggtgt
     5401 ttgctcataa ttgataagca agcccggtgc cttattgaag ggttggctat cacggtgatt
     5461 cacccgatgg gcgggaagaa gatgtagacg cagggctgga cccttaggtc ctgaagctgg
     5521 aatgttcaac ctgataggtg cgcggcaaat ttttgaggga aagtcggcag actatcgatt
     5581 ccgcacagag cggagtgagc gaaaacgctc gagtccggag gttgctcagc gcggcagatg
     5641 cggtccgtgt cttctcgaca gggtatggat tacttcacga atggatgccc ggctttttgc
     5701 cactcctcaa ggctcatgac gacagccgtt gtctggctga atcccaattc cgcgagggat
     5761 tgcgccgcga gagacgcacg atttccactc tgacactgaa ggtacagggg ctttgccatt
     5821 tggggcgcgc caggggatcc gacatgtttc caaatctgaa attcaagaac gccacgggga
     5881 atattaacgg caccaggcac atgacccgcg gcatattcct gtggttcgcg tacatcaatg
     5941 atgagagcgt cgccaggatt atcagtcact ttccgataag cttccattcc aatcgtgttg
     6001 acgtgctgct gcgcggcctg aatcttctgc atgagggcgg ggggaagggc ttgcgcaaaa
     6061 gtcgcagctg gaataggcaa caggccaccg gcgagagcga tgaatgccag aacgatcagt
     6121 gggtgcatga catgctcctt tttatcgtga actagcgggg agcggacttt ccttggaact
     6181 ctggcacgag acgctactct acgcctctcg agggaaagcc tcaaattctg tgcatcgagg
     6241 agcccggtgt gttggaagga acttgagggg gagaaggggg ggtgatggca gtaccatcac
     6301 cccgggagac aacaggcatt catcggttga tatcagaatg gaggacacct tcgcacacga
     6361 acgatgcgct ctttcatcga agcacgcatg ctcggtagca gatgtccgtt ttcgctagat
     6421 gggctatccc tgtctgcaca aggactagcc gatgatcaca tggtctccat gatcatcgcc
     6481 gggaggatcg tcatgtccgc cccggccctg cttggccaac acgacgccat cgtgatcatc
     6541 cccgggagga tcatcatgtc cgccgcggcc ctgcttggcg agaatcagtt gcgcggaagg
     6601 agatgcctcc ttcacgctgt
//
LOCUS       DAOQPD010000124         6380 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_7023_length_6380_cov_18.995573, whole genome shotgun sequence.
ACCESSION   DAOQPD010000124 DAOQPD010000000
VERSION     DAOQPD010000124.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 6380)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 6380)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6380
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7023_length_6380_cov_18.995573"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..202
                     /locus_tag="PK063_17755"
     CDS             <1..202
                     /locus_tag="PK063_17755"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98952.1"
                     /translation="DMGDDREISDETLQILAHIPQNRFIIVTASNVVKEIARRYNPRS
                     ARRFMHGRIYDRALATSHRSTR"
     gene            199..1581
                     /gene="bioA"
                     /locus_tag="PK063_17760"
     CDS             199..1581
                     /gene="bioA"
                     /locus_tag="PK063_17760"
                     /EC_number="2.6.1.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004015 -
                     adenosylmethionine-8-amino-7-oxononanoate transaminase
                     activity [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase"
                     /protein_id="HMZ98953.1"
                     /translation="MTPPSTRQPLAAWDHAYVWHPFTQMQEWEQESPLIIEKGKGSYL
                     IDTEGRKYLDGTASIWVNLHGHRHPRLDRALTAQLRQIAHSTFLGLTNPPAIRLAREL
                     IRLAPKGLRRVFYSDNGSTAVEVALKMAVQYWQQARPSNGSKQSFAHLKMAYHGDTIG
                     AVSVGNIELFHGRFKPLLFPTHQVEPPYCYRCPLGRAYPSCDMACIDPLERLLKTRHR
                     ELAGVIVEPLVQAAAGMMVAPPGYLARVRELCTKYNVLLIVDEVATGFGRTGKMFACQ
                     HEGVTPDLMAISKGLTGGYMPLAATLTTDAIYRAFLGRYDEWKTFFHGHSYTGNPLGC
                     ALALANLEIFRRERTLAQVRKKSRLLARLLQPLAELPHVGDIRQCGFMVGIELVQDRQ
                     TKTPYPLEWRIGHRVAQACRLRGLLLRPLGNVMALVPPLSISPRELTTMIAILHSAIR
                     EITEELATSR"
     gene            1756..2982
                     /locus_tag="PK063_17765"
     CDS             1756..2982
                     /locus_tag="PK063_17765"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98954.1"
                     /translation="MTTGLIIRVLCLLLFLPFSLWAEDQQPSELLLQRIQFSDTARES
                     GTAAIPFSIASPVMHTSFQATSFAPPTTSTRLKDLVPDSERPQTKGLGANSTWLKGQL
                     TAEGEVANNATNDAGLTSRIDQRDDGAKRMVRMALTGTNGPVRYGINYRSAGKAFFNS
                     PDQTVREMWAEWGLGIAKLRSSSGQTWNNVDLEPNRPRIQQDVSRIGIALVKPAWPEL
                     SLTYARSALASSYIPAGMTAQRSQSNSMEAALAYTGLSWNARLSSSYILTNDEMRGGA
                     QSTTFAQTLVASYRPLNTLTFAPTFSYRTETQSWSGAKIQTPMASVSLLYKQSQRLLV
                     SAMGGYTSTKSSDGLIETESIVGRGMFAFHLNPIYGHPTTLSLEASYTNTTNRTVAGV
                     DTEDLSGLVRILVAAL"
     gene            complement(3011..4159)
                     /locus_tag="PK063_17770"
     CDS             complement(3011..4159)
                     /locus_tag="PK063_17770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HMZ98955.1"
                     /translation="MKPLLQHLSVVLLCLTVMGCTRPDPPAPSAKPVQPSVVANGQPD
                     IQTMRIDASPSLPALTLSARVTYAEDGYSKISSPLPGPVLDVRVKLGQAVKAGDILMV
                     IDAADIARAYAAYVEEISELGLAERNYELTKDLYDAQAMSLKDLEHAENDLNRERAEF
                     KQAKELLLSLRVPAAELSKPLAQQQITSRFELRSPLTGTVVERNVTPGQIVGTASDQP
                     LFTVANLDRLQVVADVYEHDLSGIRVGALAAMTVEAYPAIEFPAKIAVIGDVVDPATR
                     TIKIRATVSNQDRRLKPEMFARLTIAGHTMRPKIVIPKQAVMERSGRQWIVVELAPGR
                     FEERPVTIDSVTDNQVTIREGLVTGERIVLSPSSINHLAASDTSAGGA"
     gene            complement(4501..5301)
                     /locus_tag="PK063_17775"
     CDS             complement(4501..5301)
                     /locus_tag="PK063_17775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent chlorinase/fluorinase"
                     /protein_id="HMZ98956.1"
                     /translation="MPVTIPLITLLTDFGDRDYFVASVKGVILNINPQAHIVDLSHHV
                     TPHDVADAAYLLKSCYRYFPDGTIHVAVVDPGVGTTRRPLLVSSSRYFFIGPDNGLFT
                     HIYQEETGVEVRHLENRQYRLDSEGATFDGRDLFAPAAAWLTKGQPIGSFGRLVPNYE
                     RLPISEPSWDKHVMAGEIAYIDRFGNLISNLTAYHIREVRGITKRADPYIRIGGVTID
                     CLVHSYGEGSADAPQALINSNGYVEVFLKEGRAADRLNVARGARIELS"
     gene            complement(5381..5950)
                     /gene="greA"
                     /locus_tag="PK063_17780"
     CDS             complement(5381..5950)
                     /gene="greA"
                     /locus_tag="PK063_17780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0070063 - RNA polymerase binding [Evidence
                     IEA];
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HMZ98957.1"
                     /translation="MSPPHGSWMRATGRYRKVQPEAGFNGHRGEDMPTPITRKGYEAL
                     KAELDRLHKVERPRVIEAIAEARAHGDLSENAEYDAAKERQGFIEARLAELKGKLADC
                     RIIDIAGRTSDTVVFGATVVLIEQEAQAKKQYTLVGQDEADLKFSRISVQSPVGRALI
                     GKRVGDLVEVTTPAKVVEYEVMEIRFEEL"
     gene            complement(6000..>6380)
                     /gene="carB"
                     /locus_tag="PK063_17785"
     CDS             complement(6000..>6380)
                     /gene="carB"
                     /locus_tag="PK063_17785"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249075.1"
                     /note="four CarB-CarA dimers form the carbamoyl phosphate
                     synthetase holoenzyme that catalyzes the production of
                     carbamoyl phosphate; CarB is responsible for the
                     amidotransferase activity; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase large subunit"
                     /protein_id="HMZ98958.1"
                     /translation="VKSEDRAVACDVAQRLVALGFRITATSGTAAYLTEQGMQVDVVN
                     KVQEGRPHIVDHIKNGDVALVVNTVRTASGHSDSLSIRREALHKGVPYYTTMRGALAA
                     VMGIEALLKKGLAIRALQEYHRVN"
BASE COUNT         1241 a         1905 c         1888 g         1346 t
ORIGIN      
        1 cgatatgggc gatgatcgag aaatttcgga tgagactttg caaatcctgg ctcatattcc
       61 ccaaaatcgg ttcattatag tgaccgcctc caacgttgtc aaagaaatcg cccgccgtta
      121 taatccgcga tcggcgcggc gtttcatgca tgggcgcatc tacgatcgcg cactcgcaac
      181 atcacaccgc agtaccagat gacacctcca tccacacgcc aaccgcttgc cgcctgggat
      241 catgcgtatg tgtggcatcc gttcacgcag atgcaggaat gggaacagga gagccccctc
      301 atcatcgaaa agggcaaagg gtcctatctc atcgatacgg aaggacggaa gtatctcgat
      361 gggaccgctt ccatttgggt gaatcttcac gggcatcggc atccccggct ggatcgtgcc
      421 ctcaccgcgc agctcaggca gatcgcgcat tcgacctttc tcgggctcac gaatccgccg
      481 gcgattcgtc tggctcgcga actcattcgc cttgccccga aggggttgcg gcgggtgttc
      541 tattccgaca acggctcgac ggcggtcgag gtggcgctca agatggcagt gcaatactgg
      601 cagcaagccc ggccgtccaa cggatcaaaa cagtcctttg cgcatttgaa aatggcctac
      661 cacggcgaca cgatcggcgc ggtcagtgtg ggcaacattg agctgttcca tgggcgtttc
      721 aagccgcttc tttttcccac gcatcaggtc gaaccgccct actgttatcg ttgtccgctg
      781 ggtcgggcgt atccatcgtg cgacatggcg tgcatcgatc cgctcgaacg cctactcaag
      841 acgcggcatc gcgagctggc tggtgtcatt gttgagccgc tggtgcaggc cgcagccgga
      901 atgatggtgg cccccccggg atatcttgcc cgcgtacgcg agctctgcac gaaatacaat
      961 gtcctgctga tcgtcgacga agtggcaacc ggtttcggac ggaccggcaa gatgttcgcc
     1021 tgccagcatg agggggtcac gccggatctg atggcaatca gcaaggggtt gaccggcgga
     1081 tatatgccgt tggctgcgac gctgacaacg gacgccatct atcgggcctt cctgggacgg
     1141 tatgacgagt ggaagacgtt cttccacggg cacagctata cgggaaatcc tctgggctgc
     1201 gctctggccc tcgccaatct ggagatcttc cgccgcgaac gcacgctcgc ccaggtgcgg
     1261 aagaaatcgc gcctgttggc ccgtctctta caacccctgg ctgagttgcc gcatgtgggt
     1321 gatattcgtc agtgcggttt catggtcggc atcgagttag tgcaggatcg tcaaacgaag
     1381 accccgtatc cgctcgaatg gcgcatcggc catcgagtgg cgcaggcctg ccggctccgt
     1441 ggactgcttc tgcggccgct cggcaatgtc atggcgctcg tccctcccct ctccatctcg
     1501 cctcgtgagc tcactaccat gatcgcaatt ttgcacagtg cgattcgtga gatcacagag
     1561 gaactcgcta cctcgcgctg aaaccgcgcg tccttcctgc tgattggtgc tctcctgcag
     1621 tcaccgttcg gtgttcacgc cggtacagtc tctcgacagg ttttgtgcac tgccagggcg
     1681 gccggaagcg tgaaagtcga gtgctacact tgatttcatg ctgttctacg cagtcacctc
     1741 ggcgagcacg gtttcatgac gacgggcctg atcatccggg tcctgtgcct gctccttttc
     1801 ctgcccttct cactctgggc cgaagaccag caaccgtcgg aactcctcct tcagcgcatt
     1861 cagttcagcg acacggctcg cgagtccggg actgccgcga ttcccttttc cattgcctca
     1921 ccggtcatgc atacgtcgtt tcaagcaacg tcctttgcgc cgccgacgac ctccaccaga
     1981 ctgaaagacc tggtgcctga ttccgaacgg cctcaaacca aaggactcgg cgccaattcc
     2041 acctggctca aggggcagct cacggcagaa ggcgaagtgg ccaacaatgc gaccaacgat
     2101 gcaggcctca cctcccgcat cgatcaacgt gatgacggcg ccaaacgcat ggtgcgcatg
     2161 gcgctgaccg gcaccaacgg gccggtccga tacggcatca actatcgatc ggccgggaaa
     2221 gcctttttca actcgccgga tcagacggtg cgggaaatgt gggcagaatg ggggctgggc
     2281 attgcgaagc tgcgcagttc ctccgggcag acctggaaca atgtggatct ggagccgaac
     2341 cggccgcgca ttcaacagga cgtgagccgt atcggcatcg cgcttgtgaa accggcgtgg
     2401 cctgagctga gcctgaccta tgcgcgaagc gccctggcga gcagctatat tcctgcaggc
     2461 atgaccgctc agcgcagcca gagtaacagc atggaagcgg ccctcgccta taccggcctt
     2521 tcctggaatg ccagactctc gtcgagttac atcctgacga acgatgagat gcggggggga
     2581 gcccagtcca cgacctttgc ccagaccctg gttgcgtcct atcgtcccct caataccctg
     2641 acgttcgcgc cgacattcag ttaccgcacg gaaacgcaga gctggtcggg cgccaagatc
     2701 cagacgccga tggcgtccgt gtctctgctg tacaaacaaa gccagcgatt actggtgagc
     2761 gcgatgggcg gctacaccag tacaaagtcg agcgacggat tgatcgaaac ggagagtatc
     2821 gtgggccggg ggatgtttgc gttccatctc aacccgattt acgggcatcc caccaccctg
     2881 tcactggaag cctcgtatac caatacgacg aatcggacgg tggcaggagt cgataccgag
     2941 gatttgtccg ggttggtacg gattcttgtc gcggcgttat agccgctgcc gatcttcgcc
     3001 gtgagccggt ctaggccccg ccagcagaag tatcgctcgc agccaggtgg ttgatggacg
     3061 aggggctgag aacaatgcgt tctccggtca cgagtccttc tcgaatcgtc acctgattgt
     3121 ctgtcacgct atcgatggtc acgggacgtt cctcaaaccg gcctggtgcg agctccacta
     3181 cgatccattg cctgccggat cgttccatca ctgcctgctt aggaatcaca atcttcgggc
     3241 gcatggtgtg gccggcaatc gtcagcctgg cgaacatttc cggtttcaat cggcgatcct
     3301 gattggaaac cgtggcgcgg attttgatcg ttctggtcgc cggatcgacg acatcgccga
     3361 tgacggcaat cttcgcggga aattcgatgg ctggataggc ttctaccgtc atggccgcga
     3421 gggcgccgac tctgatgccg gagaggtcgt gttcatacac atccgcgacc acctgcagtc
     3481 gatccagatt ggccacggtg aacagcggct ggtccgaagc tgttcccacg atttgccccg
     3541 gcgtcacatt gcgttcaacg acggtgcctg tcaacggact gcggagctcg aagcgcgacg
     3601 tgatttgctg ttgtgcgagg ggtttgctga gttccgcggc cggaacgcgc agggaaagga
     3661 gcagctcctt cgcctgcttg aattcggccc gctcgcgatt cagatcgttt tccgcatgct
     3721 ccagatcctt caaggacatg gcctgggcgt cgtagagatc cttcgtcagt tcatagttcc
     3781 gttcggccag gcccaattcc gaaatttcct ccacataggc cgcgtaggcg cgagcgatat
     3841 ccgccgcgtc gatcaccatc aggatgtcgc cggccttgac cgcctggccg agcttcaccc
     3901 gtacgtcgag caccggacct ggaagtgggg aggaaatttt tgagtatccg tcttctgcgt
     3961 acgtcactct ggccgagagg gtcagcgctg gcagagatgg cgaggcatca atgcgcattg
     4021 tctggatgtc tggttgaccg ttggcgacga ctgatggctg tacaggtttg gcggatggcg
     4081 cgggaggatc agggcgtgtg cagcccatga cggtgagaca gagcagcacg accgaaagat
     4141 gttgcagcaa tggtttcatg gaaccggtgt cctcttatct catatcggtc gatgtgtcat
     4201 tcggccatag tcctgcccct gagccggctc gaaacggtcg cccccggcag ggactcgtct
     4261 ggagggatca catcagtgta caggagcagc gaaggcggga cgcaggacca acccggaatg
     4321 gtgagctccc ccggctggat gaaatatgca gaaagatcag cctattccgt gatggccacg
     4381 tcatgcatcc cggcccgcaa gctcaccatc tcattaaaac accggcaact ttcgcctgtc
     4441 aattacggga gattgcatga ggcacggaag cagtctggcc gggatcgcgc acggcattgt
     4501 ttaactgagc tcaatgcgcg cgcctctggc cacattcaac cggtcggccg cgcgaccttc
     4561 cttgaggaac acctcgacgt acccgttgct gttgatcaga gcctggggag catcggctga
     4621 cccctctccg taactatgaa ccaggcagtc gatcgtgacc ccgccgatgc ggatgtacgg
     4681 atcggcgcgt ttggtgatcc cacggacttc ccggatatgg tacgcggtga ggtttgaaat
     4741 cagattgccg aaacgatcga tataggcgat ctccccggcc attacatgtt tgtcccagga
     4801 cggttcggaa atcggcagac gttcgtaatt ggggacgagc cggccgaacg acccgatcgg
     4861 ttgtcctttg gtcaaccagg ctgccgccgg ggcgaagaga tcacgcccgt cgaaggtggc
     4921 gccttcggaa tcgagccggt attgccggtt ttcgaggtgc cggacttcaa cgcccgtttc
     4981 ttcctgatag atgtgggtga acaggccgtt gtccgggccg ataaaaaagt agcgagagga
     5041 cgagaccagc agggggcgcc tggttgtgcc gacgcccgga tcgacgacgg cgacgtggat
     5101 ggttccgtcg gggaaataac gatagcagga tttgagcaga taggcggcat cggctacatc
     5161 gtgcggtgtg acatgatgcg aaagatccac gatgtgcgct tggggattga tgttgaggat
     5221 gacgcctttc acgctcgcca cgaaataatc gcggtcgccg aaatccgtca gcagcgtgat
     5281 gaggggaatg gttaccggca tgagacccac cgggcctgcg acggtgaacg gaacggcgcg
     5341 agggaggaac gcgtgaatga cgtgaggggc gacatcacgg ctataattcc tcgaagcgga
     5401 tttccatcac ttcgtattcc accactttgg caggagtcgt cacctcgacc aaatccccga
     5461 cccgcttgcc gatgagggcg cggccgaccg gcgattgcac tgaaatgcgg gaaaatttga
     5521 gatccgcttc atcctgtccg acgagggtat actgtttctt ggcctgcgct tcctgctcga
     5581 tcaacacgac ggtggcgccg aagacgacgg tgtcgctggt gcggccggca atgtcgatga
     5641 tccggcagtc cgccagcttg cccttcaact ctgccaggcg tgcttcgatg aagccctgtc
     5701 gttccttcgc ggcatcgtat tcggcattct cgctcagatc gccatgcgcg cgcgcttcgg
     5761 cgatagcctc gatgacgcgc ggccgttcca ctttatgcag ccggtccaat tcggctttca
     5821 gcgcttcgta tccttttctc gtgatcggtg tcggcatatc ttccccccga tgaccattga
     5881 aaccggcttc cggttggacc tttcggtatc gtccggttgc ccgcatccag gaaccgtgcg
     5941 gcggactcat gtccgttcct ggaacctgtt gtcaattgtc cctctgtcag gaccttcgct
     6001 caattcaccc ggtgatactc ctgcaatgct cgaatggcaa gccccttttt cagcaacgct
     6061 tcgatcccca tcaccgctgc cagggctccg cgcatcgtgg tgtagtacgg cacgcctttg
     6121 tgtagcgcct cacgacgaat agacagcgag tcggaatgtc cggacgcggt gcgtacggtg
     6181 ttgacgacca aggccacgtc tccgttcttg atatggtcga cgatgtgcgg ccgcccttcc
     6241 tgcaccttgt tgacgacgtc gacctgcatc ccctgctcgg tcagatatgc cgcggtgccg
     6301 gaggtcgccg tgatacggaa acccagcgcg accagccgtt gggcgacatc gcaggccaca
     6361 gcgcggtctt cacttttgac
//
LOCUS       DAOQPD010000125         5975 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_7845_length_5975_cov_25.130405, whole genome shotgun sequence.
ACCESSION   DAOQPD010000125 DAOQPD010000000
VERSION     DAOQPD010000125.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 5975)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5975)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5975
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7845_length_5975_cov_25.130405"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            132..593
                     /locus_tag="PK063_17790"
     CDS             132..593
                     /locus_tag="PK063_17790"
                     /inference="COORDINATES: protein motif:HMM:NF015693.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HMZ98959.1"
                     /translation="MSLRVGIALFFIITSILILVGYLGGISYSDLMPRTFSIRDAPVE
                     PQQKSAGLVINLPPIIAPVDDGQRFYYVQANLAVEIDRPATSTVIRDRHDTIDRYIME
                     MLHNYPIQDLRTPGRSVTLRDDLKQTVNKVLPKGHVRNVYITSWLITPIGY"
     gene            781..1071
                     /locus_tag="PK063_17795"
     CDS             781..1071
                     /locus_tag="PK063_17795"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98960.1"
                     /translation="MSIEEDKIEAIRDYLLDALPGYDVRDGSRTHVDRTLTVFHDMEI
                     VCTIQIPTVLLDEDHPSVLELERALQRNNVAAWVLSAPVVYLHHNTLGLPTQ"
     gene            complement(1479..1565)
                     /locus_tag="PK063_17800"
     tRNA            complement(1479..1565)
                     /locus_tag="PK063_17800"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1529..1531),aa:Leu,seq:cag)
     gene            complement(1654..3129)
                     /locus_tag="PK063_17805"
     CDS             complement(1654..3129)
                     /locus_tag="PK063_17805"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98961.1"
                     /translation="MTAMPGTLPDLLDQLAAALERDAAQCVDQGRDQAVALVRGRLLQ
                     TIGTLHLYEFFLPPEVRISADLAASLLLGEETEPTEGLVLFQEGERLVLQVFDAIGEV
                     VPHATLVPDSSGLALTISRRLAEMSKAGTSYTLGPAERLLPIIEAGQSGDRATLAAVT
                     PTSVLTPLWQEDEAARRQKVATLVVELIRANKRILLVTPDHQSADLITLVVARVMKAA
                     GLTFKSWLSRYEVATSKETGGIPLPDLGFEAQMHQFYAKSRSDKAALRKKYDRFRELT
                     PILAYKAQKQKDLDEVRLLEWRLVTQLSDYQAKIKDIDATLAQYEQLPIWKRLSMQAM
                     GKNVESLREYKVIYERYSAGLRKEVDIAKQRIEELIPEATVPKELKPEFAELKEDVIH
                     LGGTKKIRELLAAEENTNRQAFVQNRRVIITTAARVAADPLFQKVRFDVLIAEEAPRI
                     PSPFLLAAAGLVRERIVLSGDLREVVPHGAWSLEDGFSRIV"
     gene            3417..3902
                     /gene="rplI"
                     /locus_tag="PK063_17810"
     CDS             3417..3902
                     /gene="rplI"
                     /locus_tag="PK063_17810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HMZ98962.1"
                     /translation="MKVILQETLEGVGDLGDLLDVSNGFARNYLLPRKKAVEANSRNI
                     KEFEHAKRAAAEKAKKEKQEIEAHGKKISTVSLTIAAQVGKDDKMFGSVTAKDIAEGL
                     AEQGFTVDRRKIQLAQPIKELGTFAIAIKLPREVTATIAVHVVKKQEETEAAEEAAPT
                     A"
     gene            3957..5234
                     /gene="glyA"
                     /locus_tag="PK063_17815"
     CDS             3957..5234
                     /gene="glyA"
                     /locus_tag="PK063_17815"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013246779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HMZ98963.1"
                     /translation="MQDLIGSLDALKSTDPETYEAIVAEEQRQRDKLLLIASENFASP
                     AVLSAQGSVMTNKYAEGYPGKRYYGGCQHVDTVESLAIDRAKQIFGAEHVNVQPHSGS
                     QANMAAYLAVLKPGDTILGLDLAQGGHLTHGSKVNFSGIIFRAFSYGVDRQTETIDYA
                     AVRKIAEECRPRMLVVGASAYARTLDFAKFQDIAKSVGAYLLVDIAHIAGLIAAGLHP
                     NPVPYADFVTTTTHKTLRGPRGGVTMCKAEHAKAVDKIIFPGLQGGPLMHVIAAKAVA
                     FKEAMSPAFKRYQQQVLANARTLAQGLVDRGYKIVSGGTDTHLMLVNLTNKGITGKEA
                     DAALDAAGIIVNKNAIPYDEKPPAVASGIRIGSPIVSTRGMREAEMREIVALIDRVLQ
                     HPQDQQVQAEVRAQAKTLCNRFPIFHAYDSSPA"
     gene            5250..5714
                     /gene="nrdR"
                     /locus_tag="PK063_17820"
     CDS             5250..5714
                     /gene="nrdR"
                     /locus_tag="PK063_17820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014962030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HMZ98964.1"
                     /translation="MKCPFCDDVEDKVVDSRMAKEGEVIRRRRECLSCKRRYTTYERV
                     EETMPAVVKKDGRREPFDRSKIVSGLKKACEKRPISTATIETVTDRIEKRIQDMGETE
                     IVSTAVGEEVMKELSQLDQVAYVRFASVYREFKDIDQFMDEIKSLAQQRRER"
BASE COUNT         1394 a         1752 c         1674 g         1155 t
ORIGIN      
        1 cacgctcgac tacgtacaga catataggaa ataggtggta ccattgtcca gaacgtcggc
       61 aggggtgaaa gacgatttca gatcgtaccc cttcgtcaca tccggtcgct ccaacgttca
      121 ttcagaggat catgtcatta cgcgtcggca tcgcgctctt tttcatcatc accagcattc
      181 tgatcttggt gggctatctt ggaggcatct cttattcgga cctcatgccg cgcacatttt
      241 ccatcagaga cgcgccggtc gagccacagc aaaagtcggc aggtcttgtg atcaatctgc
      301 cgcccatcat cgcgcctgtc gatgacggac agcggttcta ctatgttcag gcaaacctgg
      361 ccgtggagat cgaccgaccg gcaaccagca ccgtcatcag agaccgccac gacacgatcg
      421 atcgatacat catggagatg ctgcacaatt atccgattca agatttgcga acgcccggcc
      481 gctcagtgac attacgagac gatctcaagc agacggtcaa taaagtcctg cctaaaggac
      541 atgtccgcaa cgtgtatatc accagctggt tgattacacc gattgggtac tagcccttcc
      601 ttctccgctc cccttttcca gcactgatgc cagggctctc cctagcttaa caatgtcccg
      661 cagttccggt acgtggtgtg taggcacagg cgccatgaca tggcttgatg tgcccgcgta
      721 cactgttgac cgattcgcag gatgcggcgt catgttcgca agaccgagag ggactgaatc
      781 atgagtattg aggaagataa gattgaagcg atccgagact acttgctgga cgcgctgccc
      841 ggctacgatg tgcgagacgg ctcccgcaca catgtcgatc gcacgttaac ggtgtttcac
      901 gacatggaaa ttgtctgcac cattcagatt cctacggtct tactggatga agatcaccct
      961 tctgtcctcg agttagaacg ggcgctacag cggaacaatg ttgccgcctg ggtcttgtcg
     1021 gctcccgtgg tctaccttca tcacaatacc ttaggtctcc caacccagta agacaggagc
     1081 gttcaagctg atgggcgtaa agactggacg ggctgtaggc tacacgcctc taaacgagct
     1141 gactatagat cggaaaccgg gcagaaggat aaacgacagt acgctgccga ctgtgagaac
     1201 gagcaggaga agagcaaacg agaggctgag ctttatcaga aagcgtacgc aataaaacag
     1261 cagaaccacg ccaaccacta gaacgatgag agatgaaatg tccatgtgat gtaacaacac
     1321 atctacgcgc ttgaggagtt cagttcaaga gggacgactt aagaaaacct cagcctatgg
     1381 cgaggcacat tagaggcact gagacaggat aacaaagccc gcgcggcgtg aagtagcgcg
     1441 gaggagtttg gctaatgaat cggtgagaga aggaaaggtg gtgccgaagc cgggagttga
     1501 acccggatac ccttacgggc gctggtacct gaaaccagtg cgtctgccag ttccgccact
     1561 tcggcatgaa gaataggaga gggattatcg ctgatcgatc ccaacccgtc aaggtgagtg
     1621 aggggaaaat ctgcaccgcc gggccgggta tgatcacacg atgcgagaga agccgtcctc
     1681 aagactccag gccccatgcg ggaccacttc ccgcagatcg ccgctgagca caatgcgttc
     1741 gcgcaccagt cccgccgcgg ccaacagaaa ggggctcggg atacgaggag cttcctcggc
     1801 aatcaatacg tcgaaccgta ccttttgaaa taaggggtcc gccgccactc gcgccgccgt
     1861 cgtaatgatc acccgccggt tctgcacgaa cgcctgccgg ttcgtgtttt cttcggctgc
     1921 caggagctcg cggatctttt tcgtgccccc taaatgaatg acgtcttctt tgagttcggc
     1981 aaattccggc ttgagctcct tgggaaccgt cgcctcggga atcaactcct cgatccgctg
     2041 cttggcgata tcgacttctt tgcgaaggcc ggcactgtac cgctcataga tgactttgta
     2101 ttcgcgcaac gattcgacat tttttcccat cgcctgcatg gacagacgtt tccaaatcgg
     2161 cagctgttca tattgcgcca gcgtggcgtc gatgtctttg atcttcgcct ggtagtcgct
     2221 caactgcgtg accaggcgcc attccaggag gcgcacttca tccaagtctt tttgcttttg
     2281 ggccttatag gcgaggatcg gggtgagttc gcgaaatcga tcgtacttct tacggagcgc
     2341 cgccttgtcc gaccgggatt tggcatagaa ctgatgcatt tgcgcctcaa atcccagatc
     2401 cggcaggggg ataccgccgg tctccttact ggtcgccact tcgtatcggc tcaaccagct
     2461 cttgaaggtc agtccggcgg ccttcatgac ccgcgcgacc acaagggtga tcaaatcggc
     2521 gctctggtga tccggggtga cgagcaggat gcgcttgttg gcacggatca actccacgac
     2581 cagcgtcgcc accttttgtc ggcgcgcggc ctcatcttcc tgccaaaggg gtgtcaagac
     2641 cgaggtcggg gtcacagctg ccaatgtggc ccggtccccg gattggcccg cctcgataat
     2701 gggaaggaga cgttctgctg gacccaacgt atacgaagtg cccgccttac tcatttcagc
     2761 caatcgacga ctgatcgtga gagccaaccc gctggagtcc ggcaccagcg tggcatgcgg
     2821 gaccacttcg ccgattgcat caaagacctg aagcaccaga cgctcgcctt cctggaacaa
     2881 gacgagacct tccgtcggtt ccgtctcctc acccagcaac agactggccg cgagatcggc
     2941 actgatccgc acctcaggcg gaaggaaaaa ttcgtacaga tgcagggtcc cgatcgtctg
     3001 aagcaaccgt ccgcgtacga gcgccacggc ttgatcgcgc ccctgatcca cacactgtgc
     3061 ggcgtcacgt tcgagcgcgg cagccaactg atcaagaaga tccggcaacg tgccgggcat
     3121 ggcggtcatg atgggtcgtg ctcctgcatt tcgttggggc gcatccgtga caggctgggc
     3181 catgaaacag ggaccgtatc ttaaagactc gggaaagacc ctgtccagca gcgatcagac
     3241 gttcccctgt tcgaaatctt caaaacccgc ataactagcg gtactccatg gcgagcaggc
     3301 acaggccttc ccattcccag accacgaaga aaacccctct cggccgctcc ggatcaattg
     3361 acttttgcac agcccgccag tatgcttttt ccctttccaa cagaaggagt tgcagtatga
     3421 aggtgattct ccaggaaaca ctcgagggcg tgggcgacct cggcgatctg ttagacgtct
     3481 cgaatgggtt tgctcggaac tatctgttgc cgcgcaagaa ggccgttgag gcgaacagcc
     3541 ggaatatcaa agaattcgaa catgccaagc gcgcggccgc tgaaaaagcc aagaaagaaa
     3601 agcaagagat cgaagcccat ggcaagaaga tctcaaccgt gtcgctgacc attgccgcac
     3661 aggttggcaa ggatgacaaa atgttcgggt ccgtgacggc caaggatatc gcggaaggtc
     3721 tggccgaaca gggatttacc gtcgaccgtc gcaagatcca attggcccag ccgatcaagg
     3781 aactgggaac gttcgccatt gcgatcaagt tgccgcgcga agtgaccgcc acgattgcgg
     3841 tccatgtggt caagaaacag gaagagacgg aagctgccga agaagccgcg cccacggcct
     3901 agttcgcgcg atcatgcgtg gccaccgctg aatcagaggc cgcgcccgga ggaagcatgc
     3961 aggatttgat cggttcgttg gatgcgttga aatcgaccga cccggaaacg tacgaggcca
     4021 tcgtcgccga agagcagcgg cagcgcgata agttgctgct gatcgcatcg gagaactttg
     4081 ccagccccgc cgtcctgtcc gcccagggca gcgtgatgac gaataagtac gccgaagggt
     4141 accccggcaa acgctattat ggcggatgcc agcatgtcga taccgtcgaa agcctcgcca
     4201 tcgaccgcgc caaacaaatc ttcggagccg aacacgtcaa cgtgcaaccg cactcgggat
     4261 cgcaggccaa catggcagcc tatctcgcgg tgctcaaacc cggcgacaca atcctcggac
     4321 tggatctggc ccagggtgga cacctcacac acggcagcaa ggtcaacttc tccggaatca
     4381 ttttccgcgc cttttcctat ggcgtcgatc gccagacaga aaccattgac tacgcagcag
     4441 tccgcaagat cgccgaagag tgccgcccgc gcatgttggt cgtcggtgcc agcgcctacg
     4501 cccgcacgct cgactttgcg aagttccagg acatcgctaa atcggtcggc gcctatctgc
     4561 tggtggatat cgcccacatc gccgggttga tcgcggccgg gttgcatccc aaccccgtcc
     4621 cctatgccga cttcgtcacc acgacgaccc ataagacgtt acgtggccct cgaggcggcg
     4681 tgacgatgtg caaagccgag catgcgaagg ccgtcgataa gatcattttc cccggcctgc
     4741 aagggggtcc gctcatgcat gtgattgccg cgaaagccgt cgccttcaag gaggcgatgt
     4801 ctccggcctt caagcggtat caacagcaag tgctggccaa tgcccgcacc ctggcgcaag
     4861 ggctggtcga tcgtggctac aagattgtgt ccggaggaac cgatacgcat ttgatgttgg
     4921 tgaacctgac caacaagggc atcacgggaa aagaagccga cgctgccctg gacgcagcag
     4981 gcatcatcgt caacaaaaac gccatcccgt atgatgaaaa gccgccggcc gtggcgagcg
     5041 gcattcgcat cggcagcccg attgtgtcga cacgcggcat gcgcgaagcg gagatgcgcg
     5101 aaatcgtggc gttgatcgat cgtgtgttgc agcatcccca agaccagcag gtgcaggccg
     5161 aggtacgggc gcaggccaaa acattgtgca accgtttccc catctttcat gcctacgatt
     5221 cgtctcccgc ttaggcagga cggccgcccg tgaaatgtcc tttctgcgac gatgtcgaag
     5281 acaaagtcgt cgattcgcgg atggccaaag aaggcgaggt catccgccgg cggcgtgaat
     5341 gcctctcgtg caaacgccgt tacactacct acgaacgtgt cgaagagacc atgcccgccg
     5401 tcgtgaaaaa ggacggccgc cgggaaccat tcgatcgaag caagatcgtg tccggactca
     5461 aaaaggcctg tgaaaagcga ccgatcagca ccgcgaccat cgaaaccgtc accgaccgca
     5521 tcgaaaaacg catccaggat atgggcgaaa ccgagatcgt cagcaccgcc gtcggcgaag
     5581 aagtgatgaa agagctgtct caactcgatc aggtggccta cgttcgattc gcgtcggtgt
     5641 atcgagagtt taaagacatc gatcagttca tggatgaaat caaatccctg gcccagcagc
     5701 gccgggagcg ttaggccctc ccctccttcc cgctgttccg gatcagagtc cgtgtgaaga
     5761 gacccaggca ggataggtgc caacagagga gaaccgccgt ccatcggatt gtctgactga
     5821 tatggccaca accaaaacat cacaagaacg acgaacgacc cgccgcccga ccaaacggcg
     5881 atcaccgggc gctacgcacg tcgtcatcat cggcgcgggg cgcgggggca cggccttgat
     5941 ggaaattttc gccaacgacc cgctggtacg catcg
//
LOCUS       DAOQPD010000126         5966 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_7861_length_5966_cov_12.558958, whole genome shotgun sequence.
ACCESSION   DAOQPD010000126 DAOQPD010000000
VERSION     DAOQPD010000126.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 5966)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5966)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5966
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7861_length_5966_cov_12.558958"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..808
                     /locus_tag="PK063_17825"
     CDS             <1..808
                     /locus_tag="PK063_17825"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HMZ98965.1"
                     /translation="DVTTLGRGGSDLTAVALAAALKADRCIIYTDVDGVYTADPNIVP
                     AARRLEKISYEEMLEMASLGAKVLQSRSVEFAAKYSVPVEVNSSFKEGKGTLVTREDA
                     DMEGVMVSGVTGDRNQAKITIIGVPDRPGIAARVFGAVANANIVVDMIIQNVSQASMT
                     DISFTVPKPDLRKAVDLVQRLSEEIGARSVAVTESIAKVSLIGVGMRSHSGVAAKMFE
                     VLSREGVNIMMISTSEIKISCVIEEKYLELAMRTLHTAFGLDRVSAPALG"
     gene            929..2518
                     /gene="cimA"
                     /locus_tag="PK063_17830"
     CDS             929..2518
                     /gene="cimA"
                     /locus_tag="PK063_17830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043714 - (R)-citramalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citramalate synthase"
                     /protein_id="HMZ98966.1"
                     /translation="MPSLTAVQASALEIYDTTLRDGAQAEDVSFSVEDKLRVAQQLDA
                     LGVHFIEGGWPGANPKDIEFFRQIKTIPFRNATVVAFGSTRKASNPVRKDKNLQALLD
                     SGTPTITLFGKSWSFQVTDALGIALAKNLELIEDSIHYLRSKNRRVFYDAEHFFDGYK
                     ANPDYALQTIRRAIAGGAERVILCDTNGGTMPWEIREICRVVKQECPVPLGIHAHNDS
                     EMAVANSLVAVESGILQVQGTINGIGERCGNANLCSIIPNLQLKMQRPALGDNLAHLK
                     DVSGFVTEIANLMPNKRQPYVGDAAFAHKGGVHIHAVLKNAATYEHIDPAVVGNRRRI
                     LVSDYAGRSGLLEKVEAYGISLTKNHAKLQELVETLKERESQGYQFEGAEGSFELLMR
                     NAMGSHRPSFKLLGFRVIVEKKQEHGLLLSEATVMVQVGDVVEHTAAVGAGPVNALDH
                     ALRKALEKFYPQLREVKLLDYKVRVLSAEKGTESKVRVLIESGDHKDKWGTVGVSENI
                     MEASWQALADSIEYKLLLADR"
     gene            2664..2939
                     /locus_tag="PK063_17835"
     CDS             2664..2939
                     /locus_tag="PK063_17835"
                     /inference="COORDINATES: protein motif:HMM:NF001401.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit alpha"
                     /protein_id="HMZ98967.1"
                     /translation="MRKADIANEIFKQVGVSKNDAADIVELVLNLLKGVLQKGDAVKI
                     AGFGNFVVRSKGARKGRNPRTGEEIGITPRRVVTFRPSQVFKKYVNS"
     gene            2981..3334
                     /locus_tag="PK063_17840"
     CDS             2981..3334
                     /locus_tag="PK063_17840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HMZ98968.1"
                     /translation="MGNDPRLGSKVFYKIGEVSKISKLPAYVLRFWESEFTFLKPKKS
                     RGNQRLYVQRDVDTVLEIKRMLYDEGHTLAGVKRYWARRGRATVKKSGSRKELAQRVR
                     GDLQAIIRMIDSHSA"
     gene            3397..3473
                     /locus_tag="PK063_17845"
     tRNA            3397..3473
                     /locus_tag="PK063_17845"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3431..3433,aa:Pro,seq:ggg)
     gene            3637..4452
                     /gene="surE"
                     /locus_tag="PK063_17850"
     CDS             3637..4452
                     /gene="surE"
                     /locus_tag="PK063_17850"
                     /EC_number="3.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008252 - nucleotidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'/3'-nucleotidase SurE"
                     /protein_id="HMZ98969.1"
                     /translation="MARVRILVTNDDGIASPGIHAVATALGALGEVWIVAPDRERTAV
                     GHAVTLHKPLRITKMAPRVFMVNGTPVDCVNLALLKIMPHQPALIVSGINRGVNLGDD
                     VMYSGTVSGALEGTMFGIPSVAVSQEGEDTFRFEVGARYATRVASEVLVHGLPPETIL
                     NVNIPDVPLRGIKGVKVTCLSRRRFNNPIVEKVDPRGRKYYWIAGTRQSWSRQQDADH
                     EALARHMVSVTPIRLDTTHHTMLAHFKTWEGTLSRPLVARTQVRRRSSRRPQS"
     gene            4449..5084
                     /locus_tag="PK063_17855"
     CDS             4449..5084
                     /locus_tag="PK063_17855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HMZ98970.1"
                     /translation="MSGLIEWLIEVLGRFVIATISTFGYTGIVITMAIESACIPLPSE
                     IIMPFSGYLVSTGQFSLVGVTLAGAIGNVLGSLVAYYVGVWGGRPFVERYGRYVLISQ
                     HDVDLADRWFAKHGEAAVLIGRLLPVVRTFISLPAGIARMDIKKFVLYSFVGAVPFCY
                     ALAYVGLKMGEHWNELHQYFHHADLVIGLFLAIGLGYFLWSHWPKRRASVG"
     gene            5094..>5966
                     /gene="cysS"
                     /locus_tag="PK063_17860"
     CDS             5094..>5966
                     /gene="cysS"
                     /locus_tag="PK063_17860"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HMZ98971.1"
                     /translation="MLRVYNTLTGHKDLFEPMVPGMVRMYVCGVTVYDYCHIGHARSA
                     LVFDVLRRHLEYSGLIVEFAKNFTDVDDKIIKRANEQGVSCEHITTTFIKAYYDDMDK
                     LGVRRATLEPRATEHIADIVALVDTLMAKGMAYRVERDVYFQVDRYPVYGRLSKRKMD
                     DLQAGARVDVDERKRHPMDFALWKGSKPGEPSWDSPWGLGRPGWHIECSAMAMRHLGE
                     TFDIHGGGMDLIFPHHENEIAQSCGATGKEFARYWVHNGFVQINHEKMSKSLGNFFTI
                     REIFEKSEWPDAVTG"
BASE COUNT         1261 a         1489 c         1867 g         1349 t
ORIGIN      
        1 ggacgtcacg acgttgggac gcggtgggtc tgacctgacg gctgtggctc tggctgctgc
       61 gctcaaggcc gaccgctgca tcatttatac ggatgtcgat ggcgtatata ctgctgatcc
      121 caatatcgtg cccgccgcgc gtcgtctcga gaagatttcg tacgaggaaa tgttggaaat
      181 ggccagcctc ggagcaaaag tgctccagag tcgttcggtc gaatttgcgg ccaaatattc
      241 cgttccggtg gaagtcaatt caagcttcaa ggaaggaaag ggaacgctcg tgacacgtga
      301 agatgccgat atggaagggg tgatggtgtc gggtgtgacg ggagaccgca atcaggccaa
      361 aattacgatc attggggtgc cggaccgccc gggaattgcc gcgcgtgtct tcggggccgt
      421 ggcgaacgcc aatatcgtcg tcgacatgat cattcaaaac gtcagtcagg cctctatgac
      481 cgacatctcg tttacggttc ccaagccgga tttgcgcaag gccgtggatc tcgttcagcg
      541 gttatcggaa gagatcggcg ctcggtcggt tgcggtgacc gaatcgatcg ccaaggtgtc
      601 cctcattggt gtgggaatgc gctcgcattc aggcgtggcg gcaaagatgt tcgaggtgtt
      661 gtcgcgtgaa ggcgtcaaca tcatgatgat cagcacctcc gaaatcaaaa tctcctgcgt
      721 cattgaggag aaatatctgg aattggcgat gcgcacgctc catacggcgt tcggtctgga
      781 ccgtgtgtcg gcgcccgcgt tgggctgatc gtctcgaaat ggcgatcgcg tgagccctcg
      841 acagatcctg tccggccttg ttacccttta attcatgaca cgtcgaacca caccctctcg
      901 tcgcgctcgc gtcccggaat cgatctcgat gccgagcctc accgctgtgc aggcatcggc
      961 gttggaaatt tacgacacga cgttacgaga cggcgcccag gccgaagacg tgagtttttc
     1021 cgtggaggat aagcttcggg tggcacagca gctcgacgcg ctcggggtgc acttcatcga
     1081 gggtgggtgg ccaggggcga atcctaagga cattgagttt ttccggcaga tcaaaaccat
     1141 tccgtttcgg aatgcgaccg tcgtcgcgtt cggctcgacg aggaaagcca gcaacccggt
     1201 tcgtaaagac aaaaatcttc aggcgctgct ggattcgggc acgccgacca tcaccctgtt
     1261 cggcaagagt tggtcgtttc aggtgacgga tgcgttggga atcgcccttg ccaagaatct
     1321 agaactcatc gaagactcta ttcattattt gcgatccaag aatcggcggg tgttttatga
     1381 cgccgaacat tttttcgacg gctataaggc gaatcctgat tatgcactgc aaaccatccg
     1441 tcgagcgatt gccggcggag ccgagcgtgt gatcttgtgc gatacgaacg gcgggaccat
     1501 gccgtgggag attcgcgaga tttgccgggt ggtcaagcag gaatgtcccg tgccgttagg
     1561 catccacgcg cacaatgaca gtgaaatggc cgttgccaac tcgctggtag ctgtggagtc
     1621 gggtattttg caggtgcagg gcacgatcaa tggcattggt gaacggtgtg ggaatgcgaa
     1681 tttgtgctcg atcattccga acctgcaatt aaaaatgcaa cggccggcgc ttggagacaa
     1741 cctggcccac ttgaaggacg tgtcaggttt cgtcacggag atcgccaacc tcatgccgaa
     1801 caaacggcag ccctatgttg gggatgcggc gtttgcgcac aaggggggcg tgcatattca
     1861 tgcggtcctc aagaacgcgg cgacgtacga acatattgat ccagccgtcg tcggcaaccg
     1921 tcggcggatt ctcgtctcag actatgcagg ccggagcggg ctcttggaaa aagtcgaggc
     1981 ctatggcatt tcgttgacca agaaccatgc gaagttacaa gagttggtgg agacgctcaa
     2041 agagcgggaa agccagggct atcaattcga aggtgccgag gggtctttcg aattgttgat
     2101 gcgcaacgcg atgggcagtc atcgtccgtc gttcaaatta ctgggttttc gtgtgattgt
     2161 tgaaaagaag caagagcacg ggctcctgtt gtcggaagcg acggtcatgg tgcaggtcgg
     2221 cgatgtggtc gagcatacgg cggctgtagg cgctggcccg gtgaatgcgc tcgaccatgc
     2281 gctccgcaaa gccttggaaa agttctatcc gcagctccgc gaagtgaaat tgctcgacta
     2341 taaagtgcgg gtgttgtcgg ctgagaaggg cacggaatcg aaggtgcgcg tgttgatcga
     2401 gtctggagat cacaaggata aatggggcac agtcggggtg tcggaaaaca tcatggaagc
     2461 gagctggcag gcgctggcag acagcatcga gtataaattg ttgctcgccg accggtagtg
     2521 ctattttccc tccagtgggc acacataatc cttgacaggc cagataacct cacgtaactt
     2581 atggggaaat tctttgtctt ggacgctcga caccaagaag cacttcctaa ggaacgactc
     2641 tagtggatgg cggggggaaa ggcatgagaa aggcggatat cgcgaacgaa atcttcaagc
     2701 aggttggagt gtctaaaaac gatgcagcgg atatcgtcga actcgtgctc aatctgctga
     2761 agggagtgct gcagaagggt gatgcagtga agattgcagg atttgggaat tttgtcgttc
     2821 gaagtaaagg ggcccgtaaa ggacgtaatc cgcgaaccgg tgaagaaatc ggcattaccc
     2881 cccgtcgcgt ggtgacgttt cgacccagtc aggtctttaa aaagtacgtg aattcctagt
     2941 cgctaccttg ccacgagcac acgcagcatg aggaccggtc atggggaatg atcccagact
     3001 gggaagtaag gttttttata aaatcggcga agtcagcaag atttctaaat tgccggctta
     3061 tgtcttgcgg ttttgggagt cggagttcac cttcctgaag cccaagaaaa gccgcggcaa
     3121 tcagcgattg tatgtgcagc gtgatgtgga tacggtgctg gagatcaagc gcatgctcta
     3181 tgatgaaggg catacgctag ccggtgtgaa gcggtactgg gcccgccgag gacgcgcaac
     3241 cgtcaaaaag agcgggtcga gaaaagaact ggcacaacgc gtgaggggcg atctccaggc
     3301 gatcatccga atgatcgatt cacattcagc atgaactgtt ccggtgatgc gggcggctgc
     3361 gtccaaccgt gtgggtaaca tcgatgtcgg ccgtgtcggg gcgtagcgca gcccggtagc
     3421 gcactcgctt ggggtgcgag gggtcgtggg ttcaaatccc gccgccccga ccatcggcat
     3481 gatgttctcc atcacgcagt gttctgagga acgttgagta ttgccactga ccatgtgcgt
     3541 gcacgcgtga gtgttctccc ctttcctgtg gctcccctca atctgatcgt tttgactctc
     3601 ccctttcatc acgggttcga cacataagga gcaggcgtgg cgcgtgtacg gatccttgta
     3661 accaacgacg atggaattgc gtctcctggg attcatgcgg tggcgaccgc actcggtgcg
     3721 ttgggggagg tgtggatcgt cgcaccggat cgagagcgga ctgctgtcgg gcatgcagtg
     3781 acgttgcaca aaccgcttcg catcaccaaa atggctcccc gggtcttcat ggtcaatggg
     3841 accccggtag attgtgtcaa tcttgccctg ctcaagatca tgccccatca gcctgcgctc
     3901 atcgtgtcgg gtatcaatcg cggcgtgaat ctcggcgatg atgtgatgta ttccggcacg
     3961 gtgtcgggtg ccttggaagg gacgatgttc ggcatcccgt cggtggccgt ctcacaggag
     4021 ggcgaggaca cgtttcgttt cgaggtcggg gcccggtatg cgactcgggt ggcgtcggaa
     4081 gtgctggtcc acggactacc gccggaaacg atcttgaatg tgaatatccc ggacgtcccc
     4141 ttgcggggga tcaagggcgt gaaggtgacc tgtctcagtc ggcgccgctt caataatccc
     4201 atcgtggaga aggtcgatcc gagagggcgg aagtattatt ggatcgccgg gacacggcaa
     4261 tcgtggagtc ggcaacagga tgccgatcac gaagccttgg cgcgccatat ggtttcggtc
     4321 acgccgatcc gcctcgatac gacccatcac accatgctgg cgcacttcaa aacctgggaa
     4381 gggacgctct cgcgcccgtt ggtggcacgg acgcaggtgc gccggcgttc gtcaaggagg
     4441 cctcagtcat gagcggcctg atcgaatggt tgatcgaagt gctgggtcga ttcgtcattg
     4501 cgacgatttc gacgtttggg tacaccggca tcgtgattac gatggccatc gaaagtgcct
     4561 gcatcccctt gccgagtgaa atcattatgc ccttctccgg ctatctggtc tccaccgggc
     4621 aattttcgtt ggtgggagtg acgttagccg gcgcgattgg gaatgtcctg gggtcgttgg
     4681 tcgcctatta tgtgggagtc tggggtggcc gtccgtttgt cgagcggtat ggccggtatg
     4741 tgctcatctc ccagcatgat gtggatctgg ccgatcgctg gtttgccaag catggcgaag
     4801 cggcggtctt gatcggccgc ctcttgcctg tcgtgcgaac gttcatttct ctgcccgcgg
     4861 gaattgcgcg gatggacatc aagaagttcg tgctctattc atttgtcgga gccgttccgt
     4921 tctgctacgc gctcgcctat gtggggttga agatggggga gcactggaat gagttgcacc
     4981 agtatttcca tcacgcggat ctggtcatcg gattgtttct cgccatcggc ctcggctatt
     5041 ttctctggtc acactggccg aagcgtcgcg cgtctgtggg gtaatgaccg attatgctgc
     5101 gtgtctacaa tacgctgact ggtcacaaag acctgtttga accgatggtg cccggcatgg
     5161 tccgcatgta tgtgtgcgga gtcaccgtgt atgactattg tcacatcggc catgctcgca
     5221 gtgccttggt gtttgatgtg ttgcggcggc acctggaata ctccggcttg atcgtagagt
     5281 ttgcgaagaa ctttacggat gtcgatgaca aaatcatcaa acgcgccaac gagcaagggg
     5341 tgagttgcga gcacatcact acgacattca tcaaggcgta ttacgacgac atggacaagc
     5401 tcggggttcg acgggctacg cttgagccga gggcaacgga gcacatcgcc gatattgtcg
     5461 ccctggtcga taccttgatg gccaagggga tggcctatcg cgtcgaaagg gatgtctatt
     5521 ttcaagtgga tcggtatccg gtgtatggtc gcctctccaa gcgaaagatg gatgatttgc
     5581 aggcgggcgc acgcgtggat gtggatgagc gcaaacgtca ccccatggat tttgcgctgt
     5641 ggaaaggcag taagcctggt gagccgtcat gggacagtcc atgggggctc ggtcgtcctg
     5701 gttggcatat cgaatgctcg gcgatggcga tgcggcatct tggagaaacc ttcgatattc
     5761 acggcggcgg gatggatctg atcttcccgc atcacgagaa cgagattgca cagtcgtgcg
     5821 gcgcgaccgg caaagaattc gcgcggtatt gggtgcacaa cggttttgtc cagatcaacc
     5881 acgagaagat gtccaagtcc ctgggcaatt tctttaccat ccgcgaaatt tttgaaaagt
     5941 ctgaatggcc tgatgcggtg acgggc
//
LOCUS       DAOQPD010000127         5705 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_8484_length_5705_cov_23.193274, whole genome shotgun sequence.
ACCESSION   DAOQPD010000127 DAOQPD010000000
VERSION     DAOQPD010000127.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 5705)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5705)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5705
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_8484_length_5705_cov_23.193274"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(266..601)
                     /locus_tag="PK063_17865"
     CDS             complement(266..601)
                     /locus_tag="PK063_17865"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98972.1"
                     /translation="MVTGSGSDDQQEERGSFREQLRRLETAIPGAASSVQPLLMNIHR
                     SVRRVHDQLQHIDVTPLLPRTLVSHVRCFDCGTAKMESFHTSTQGGYHLCPACFQHRL
                     RTGRAKTAH"
     gene            complement(749..2452)
                     /locus_tag="PK063_17870"
     CDS             complement(749..2452)
                     /locus_tag="PK063_17870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004819 - glutamine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006425 - glutaminyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HMZ98973.1"
                     /translation="MSTTPEPPTRSDFIREIVAADRAAGKHDGRVVTRFPPEPNGYLH
                     IGHAKSICLNFGIANEQPGGICHLRMDDTNPTTEDPEYVQAIQEDVRWLGFDWRDKMF
                     FASDYFERLYGFAVVLIKKGLAYVDSLTADEMRRYRGTLTEPGQSSPHRTRSIEENLD
                     LFSRMRAGEFPDGAHVLRAKIDMASPNINLRDPVLYRIRHVAHYRTGTQWCIYPAYDF
                     AHPLSDAIEGITHSICTLEFEDHRPLYDWVVAQCETPQRPQQIEFARLNVTFTVMSKR
                     KLLDLVERKLVNGWDDPRLPTLKGLRRRGFTPEALRAFCEAIGVAKRDAIVEMQLLEH
                     FVREDLNKRAPRVMAVLRPLRLVIENYPEGHVEQLDAINNPEDASAGTRQLPFSRVLY
                     IDQEDFKEDPPKQFFRLAPGREVRLRYAYIITCVGVVKDPTTGDITELRCTYDPETKS
                     GGAQAQRKVKATIHWVSAGHAVDAEIRLYESLMLTDPAKIPADQDWTQHLNPRSLERL
                     PSCKVEPSLASIAPGTSVQFERVGYFCADPDSAPDKLVFNRTVTLKDAWAKIEKSHTG
                     R"
     gene            2664..3794
                     /locus_tag="PK063_17875"
     CDS             2664..3794
                     /locus_tag="PK063_17875"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98974.1"
                     /translation="MLLVLLALCGLGGMDWAHAEQPASPELCRAQPYEAKMECYQQHL
                     EKVLLAEGTEGALTALEQITTQDPEALREAHPLVHHIGQQSFTRYGTAPLAMSHCRDV
                     FWSGCYHGVLQAFLSSLPAVEPEHILPLCPISETVSAYSFQRYNCLHGLGHGLTIQFR
                     YDVLKSLAFCDALPGSWDRESCYGGVFMENIVTFQQARRAQTASQHHHHEATSFLNPQ
                     DLLYPCSVLTEKYLRACYLMQTSAVLTFLNYDFAQAFTQCARVEGEHQTTCYRSLGRD
                     ISGYTLRDAQQVNALCRLGQGDQVKQCFIGAVKDFILTDANPEPGLALCRSLDGQFKR
                     DCYATVGEMVVPLFDDKNKRVQACHRGENEYVDACLATATAF"
     gene            complement(3937..4350)
                     /locus_tag="PK063_17880"
     CDS             complement(3937..4350)
                     /locus_tag="PK063_17880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98975.1"
                     /translation="MTDSPNPSIQAFLVCDSVIEDSLTKKKSLIGIFTHLQAATFPFQ
                     HHQLGLYFCLTDAEGTYHLEIDLVYVNTDQLVCRASLPDIAIHDRLQIADFGINIPAL
                     LFPAPGRYEFRLRMNSRVIAQKDFHVIQLPAPPAA"
     gene            complement(4366..4890)
                     /locus_tag="PK063_17885"
     CDS             complement(4366..4890)
                     /locus_tag="PK063_17885"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98976.1"
                     /translation="MELRKPDASHPSHEAESERHKHSLEIRLGSNIFRNTNGVIRVQG
                     KEQLVLELAPEQDRILLTIDLYDGSGNHVAHLRRNRWAFNDGNRFSLSTSDSPPTLFP
                     NLPWLKLTDQETGETVLEAAVAPGEKIHVATGKFYSHRGQLIEITSHFCRVGSTHTLF
                     GDVFEARGGTAVLG"
     gene            complement(5016..5450)
                     /locus_tag="PK063_17890"
     CDS             complement(5016..5450)
                     /locus_tag="PK063_17890"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98977.1"
                     /translation="MHGRYFGSRGCLVAGLLPALLTLAGCGASFLEGTIAPPNSSAWT
                     KCGSTTKVRVKPPKSTITVAYTEPTTGTDGKPLTNLAYTTIYYNAGDGPVIAKVVPAS
                     QKTGGAAVSQVILIPTPSQAEQEVTVCVTATDSDDREGPATP"
     gene            5619..5696
                     /locus_tag="PK063_17895"
     tRNA            5619..5696
                     /locus_tag="PK063_17895"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5655..5657,aa:Glu,seq:ctc)
BASE COUNT         1114 a         1550 c         1792 g         1249 t
ORIGIN      
        1 tggatttgcc ggacccgttc gggccgatca ggccgacatg gtcaccttcg cacaaggcca
       61 gcgtgagatt gctaaacagg gctcgtaccc cataactttt actgatcgat tcgcagctca
      121 atagaatgtt gggggccata ccctgattac ctctctcgca acagtgaaag cgtgcagtat
      181 acggtggggg aagggctcag ggctagcggc aggagggccg cttcccgggt taacgcgacg
      241 tcgagatcaa cggcgagtgg aatggttaat gagcggtctt ggcgcgtccc gtgcggagcc
      301 gatgctgaaa gcaggcgggg caaagatgat agccgccctg cgtggaggta tgaaacgatt
      361 ccatcttggc ggtgccgcaa tcaaagcagc gcacgtggct gacgagcgtc cgaggcagga
      421 gaggcgtcac atcgatgtgc tgaagttggt cgtggacccg gcggacggag cgatgaatgt
      481 tcataaggag tggttgcacg ctactcgcgg cgcccggtat cgcagtttcc aatcgtcgaa
      541 gctgctcccg gaatgaaccg cgttcttctt gctgatcgtc gctgccggat cctgtcacca
      601 tcgtaaccac cccgttgcta ggtatgaatt caccgtctgc gtgaggcgtg attctcgttc
      661 atcgacaggt gagggttcaa ggaggcagaa ggttggcgcg ccagtacttt gcgggggaat
      721 gacgctgact gaaggaggaa ggaactggtc aacggccggt gtgggatttc tcgattttgg
      781 cccaggcgtc cttgagcgtg acagttcggt tgaacaccag tttgtccggc gcagaatcgg
      841 ggtcggcaca aaagtagccg acgcgttcaa actggacgct ggtgccggga gcgattgagg
      901 ccagactggg ttccactttg cacgatggca gccgttccag cgaacgggga ttcagatgct
      961 gcgtccaatc ctgatcggca ggaattttgg ccggatccgt cagcatgaga ctttcataga
     1021 gccgtatttc cgcgtcgacg gcatggccgg ccgacaccca gtggatcgtc gccttcacct
     1081 ttcgttgtgc ctgcgctccg ccgctcttgg tttcgggatc gtaggtgcat cgaagttccg
     1141 tgatgtcgcc ggtggtcgga tccttcacga cgccgacgca ggtgatgatg taggcatacc
     1201 gcaatcggac ttcgcgccca ggtgcgaggc ggaagaattg cttgggtgga tcctctttga
     1261 aatcttcctg gtcgatgtag agcacgcggg aaaagggcaa ctgccgggtt ccagccgacg
     1321 catcttccgg attgttgatg gcatcgagct gctcaacgtg tccctcggga tagttttcga
     1381 tcacgaggcg caagggacgg agcacggcca tgacccgggg ggcgcgcttg ttcaagtctt
     1441 cgcggacaaa gtgttcgagc agctgcattt cgacgatggc atcccgcttc gccacgccaa
     1501 tggcttcgca aaacgcacgg agcgcttcag gggtaaaccc gcgtcggcgg agtcctttga
     1561 gtgtcggcag gcgcgggtca tcccagccgt tgaccagttt gcgttcgacg agatcgagga
     1621 gtttgcgctt gctcatgacc gtgaaggtca cattcagccg cgcaaattca atttgctgcg
     1681 gccgctgagg tgtttcgcat tgcgccacca cccagtcgta caggggacga tgatcttcga
     1741 attccaacgt gcagatcgaa tgggtaatgc cttcgatcgc atcggacagc ggatgggcga
     1801 aatcatacgc tgggtaaatg caccactgtg tgccggtgcg gtagtgcgcc acatggcgga
     1861 tgcggtagag caccggatcg cggagattga tgttcggcga ggccatgtcg atcttggcac
     1921 gaagcacatg ggcgccgtcg ggaaattccc ctgcgcgcat gcggctgaac aggtccaggt
     1981 tttcctcgat gctgcgggta cgatgcgggc tggactgtcc cggttccgtc agcgttccgc
     2041 gataacggcg catctcgtcc gccgtcaggc tatcgacgta ggcgaggcct ttcttgatga
     2101 gcacgacggc aaagccatag agccgctcga aatagtcgga ggcgaaaaac atcttgtcgc
     2161 gccagtcgaa ccccagccag cggacatctt cttgaatcgc ctggacgtat tccgggtctt
     2221 ctgtcgtggg gttcgtatca tccatgcgga gatggcagat cccacccggt tgctcgttgg
     2281 caatgccgaa gttgaggcaa atcgacttgg catggccgat atggagatag ccgttcggtt
     2341 ccggcggaaa gcgggtcacc actcggccgt catgtttccc ggcagcacga tcggctgcca
     2401 caatctcgcg aatgaagtct gagcgtgtcg gaggttctgg cgtggtggac atactgggcg
     2461 cgattccgtc gagttgccgg tgatgaacgc gaatggttct atcatagaac tggaggcggg
     2521 agaaggggga ttgatgaacg gcctgtgccg tgttgatttt ctctggatcg atggggagga
     2581 gtattttaga atcacttttt tatggcagat gtcccgacgt gtagtgattc agtaaggggg
     2641 attggatgat gcgtggtcaa cgaatgcttc tggtacttct ggcgctgtgt ggcctgggcg
     2701 ggatggattg ggcccacgcg gaacagccgg catcccccga gctctgccgt gcgcagccgt
     2761 acgaggcgaa gatggaatgc taccagcagc acttggaaaa ggtgttactg gccgagggga
     2821 ccgaaggagc actgacggct ctcgagcaga ttacgacaca ggatccggaa gcgctgcgcg
     2881 aggcccatcc actcgtccac cacatcggcc agcagtcatt cacgcgctat ggaacggccc
     2941 cgctcgccat gtcgcactgc cgggatgtct tctggtctgg ttgctatcac ggcgtcctgc
     3001 aggccttcct gagcagtctg cccgccgtgg aaccggagca tatccttccg ctctgcccca
     3061 tcagcgaaac ggtttcggcc tattcgtttc agcggtacaa ctgccttcat ggcttgggcc
     3121 acggcctgac cattcaattt cgctacgatg tgctgaagag cctcgcgttt tgtgatgcct
     3181 tgccgggcag ctgggaccgc gaatcctgtt atggcggcgt gttcatggag aacatcgtca
     3241 cgtttcagca ggcccgtcgc gcgcaaacgg ccagccagca tcatcaccat gaagcgacca
     3301 gttttttgaa tccgcaggat ttgttgtatc cctgctccgt cctgacggaa aaatatctgc
     3361 gcgcctgtta cctgatgcag acctctgccg tgctgacctt cctgaattac gacttcgccc
     3421 aggcgttcac gcaatgcgct cgagtggagg gggagcatca gacgacctgt tatcgaagtc
     3481 tggggcggga tatcagtggc tacacgttgc gtgatgccca gcaggtcaat gctctgtgcc
     3541 ggcttggcca gggcgatcag gtgaagcaat gtttcatcgg tgcggtgaag gacttcattc
     3601 tgaccgatgc caatcccgag cccggcctcg cgctgtgccg cagcctggat ggacagttca
     3661 aacgggactg ttatgccacc gtgggagaaa tggtcgtgcc cctgtttgac gacaaaaata
     3721 agcgcgtaca ggcctgccat cgcggcgaaa acgaatatgt cgacgcctgc cttgccactg
     3781 ccacggcctt ctagctacta gccgatcgcc tgtcctttgc ggctggccct cctcaacacc
     3841 ccgtccaggt gagcgcgagc tgcctctagc ggattcgggt tcggatgcct gacatcctga
     3901 tcgcgtatgc cttcgtgcgc tagtgagccg gccagattag gcagccggtg gcgccggcaa
     3961 ttggatgacg tggaagtctt tttgcgcaat gacacgactg ttcatgcgca ggcgaaactc
     4021 ataacggccc ggagcgggaa acagcagagc gggaatgttg atgccgaaat ccgcaatctg
     4081 caggcgatcg tgaatggcga tgtcgggaag tgaggcgcgg cagaccaact gatcggtgtt
     4141 cacatacacc agatcgatct ccaggtggta cgttccttcc gcatcagtca ggcagaagta
     4201 caggcccaat tgatggtgct gaaatggaaa agtcgcggcc tgcagatgcg tgaagatgcc
     4261 gatgagagat tttttcttgg tgaggctgtc ttcgatgaca ctgtcacaga ccaggaaggc
     4321 ctggatgctg gggttcggac tgtcagtcat acgattcggc cggcgtcagc cgagcaccgc
     4381 tgtcccgccg cgggcttcga acacatctcc gaacagggta tgcgtggagc cgacgcggca
     4441 gaagtgcgaa gtgatttcga tgagttgacc gcggtgagaa taaaatttgc ccgtcgccac
     4501 gtggatcttt tcgccgggcg ccaccgctgc ctccagaacc gtttcgccgg tttcctgatc
     4561 cgtcagcttg agccagggaa gattgggaaa cagggtcggc ggggaatcgc ttgtgctgag
     4621 cgaaaagcga ttgccgtcgt tgaacgccca ccgattgcgg cggagatgcg ccacatgatt
     4681 gccgctcccg tcatacagat cgatcgtcag caggatgcga tcttgttccg gtgccagttc
     4741 caagacgagt tgttccttgc cctgaacccg gatcacgccg ttggtattgc ggaagatatt
     4801 ggagccgagc cgaatctcca agctgtgttt gtgccgttct gattcggcct cgtgggaagg
     4861 atgtgacgcg tcaggtttgc gtagttccat gcgtagaaat ctagtgcgac ctgaggaccc
     4921 ggttggcgac gcattcggcc ctgtgtggcg gcctgagcaa gtcggatgca aggtaggccc
     4981 ttaacggggc gctgtcaagt ctgttctagc ggtgcttaag gggttgcggg gccttcacgg
     5041 tcgtcggaat cggtggccgt cacacagacg gtcacttcct gttccgcctg gctcggcgtg
     5101 ggtatcagga tcacttgaga aacggctgcc ccgccggtct tttgtgatgc cggcacaacc
     5161 ttggcgatca cggggccatc cccggcgtta tagtaaatgg tggtataagc cagattggtc
     5221 agaggtttgc cgtccgtgcc ggtggtgggc tcggtgtagg cgacggtaat agtggattta
     5281 ggtggcttca cgcgcacttt ggtcgtgctg ccgcacttcg tccaggcgct ggagttgggc
     5341 ggcgcgatcg tgccttccag gaaactggca ccgcagccag ccagcgtcag cagggctgga
     5401 agcaggcctg cgacaagaca acctcgagat ccgaagtaac gaccatgcat actcgtactc
     5461 taggctaatt caaaagcctc tgcaagcagg tctggttcat gccatggata cttgcctcgt
     5521 gtggccccgg tgtccgctcc ttctgacttg ccgtttgaaa agccaaaact cgctatggta
     5581 cagtccggtt ctttccgctg cagttggact acctctccgg tcccatcgtc tagcttggcc
     5641 taggacggag ccctctcaag gctcagacac gggttcaaat cccgttggga ccaccaacct
     5701 tttca
//
LOCUS       DAOQPD010000128         5645 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_8635_length_5645_cov_22.313059, whole genome shotgun sequence.
ACCESSION   DAOQPD010000128 DAOQPD010000000
VERSION     DAOQPD010000128.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 5645)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5645)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5645
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_8635_length_5645_cov_22.313059"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..699
                     /locus_tag="PK063_17900"
     CDS             <1..699
                     /locus_tag="PK063_17900"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HMZ98978.1"
                     /translation="AISAGLEHCRGRVVSIMDADLQDPPEVLHTFLAKWQEGWEVVYA
                     VRTERKEWWGKRLAYAGFYRLLQRVANIEIPLDAGDFCVMDRKVVDLLVRMPERNRFV
                     RGIRSWVGFKQVGVPYERQARHAGTPKYTLRKLIYLALDGLVSFSHMPLRIITLLGFT
                     VSLLSFLVALFYLIKKFTIGVGVAGFTTLVVSIFFLAGIQLMTIGVIGEYIGRISDEV
                     KHRPLYVARRVTRR"
     gene            717..1928
                     /locus_tag="PK063_17905"
     CDS             717..1928
                     /locus_tag="PK063_17905"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024831.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HMZ98979.1"
                     /translation="MFDNEFPPLGGGTGVVNLHLLEEMALRPDVTVDLVTSSRTKARY
                     ETEAFADRITIYKVPVDNRNIHHATNRELLRYSWRGLRLARQLASEHQYDVSFAFAGV
                     PAGAISYLLRLTHGLPYVLSLQGPDVPGFEARYNYLYPVLTPFITQIWRRAGVVTAIS
                     AEQVALAHRTIPDLPLITIPNGVDTNAFVPATRNSRRPFTMICVARLIERKGQHHLLQ
                     AFANLRAANHEPMALIFVGTGDAEPQLRELAAKLQVAEAVTFKGFVPRENMPPVYHDA
                     DVFVLPSQHEGMSIALLEAMASGLPVIVTDTGGTAELVTQGANGEIVPWDDVEALTTA
                     LQRLLNAAEQRRRMGDESRRRALAFGWPTLAARYLELCARVMVPSAESRAKDARSAKN
                     VARDWTRELRG"
     gene            1934..3034
                     /locus_tag="PK063_17910"
     CDS             1934..3034
                     /locus_tag="PK063_17910"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024831.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HMZ98980.1"
                     /translation="MPHVCILTSQYFDWGIYGGFGSMSRKLAESLVRAGHRVSVIVPG
                     RQGQQPTETIGGVEIRSFSPRNVMDACRLIRESRADIFHSQDPTVLTYLAQRIHPRRA
                     HLVTSRDPRELSDWWVEFLYATPMRRLLTPLNYFTESGFLVRQAVRRADAVYCPAHFL
                     KEKVKRLYGLKQLPTLLPNLIDVPSALPRKSERPTITFIARWDKRKRPWLFLELAAQF
                     PDYRFVAVGKGSASAETGFDAELRQRFRNVPNLEMPGLINRFHEPERMHQILSDTWVF
                     VSTAVREGLPLTFLEAAAYGCPIISRVDPDQFATRFGKQVHDDDYAAALQSLLAEAPL
                     EKGRAAYHYVRDTYETSRALIAHQEQYARFAA"
     gene            3096..4640
                     /locus_tag="PK063_17915"
     CDS             3096..4640
                     /locus_tag="PK063_17915"
                     /inference="COORDINATES: protein motif:HMM:NF024832.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HMZ98981.1"
                     /translation="MSAKAVSKGILSVGGWSMAKLATSAVVLPILARFLGIEGYGQYA
                     YYLAVLLLASQFANVGMMQTMTRRIAERPDDAAWCRGVARSGALINGTGVVFVGLAAG
                     VLIWGTASHETARVPIALAVVGVLVFDQVWFYARGVLHGLRHEERAAVPGIMGVLMAG
                     SFGIIAAVTGMGVVGVLVGLLVADIFVAGACLRAVMVALNGLGLPASQGPPALPTGAV
                     LRFGLSAMIFSVLNMALCSLDIILVRHLAGEAQAGLYAAAVQWSQFVWFIPIAVEGVM
                     LQATARLWAEQRVEAVTSLVSRLVRYVMLGTVFLLIVVFVLGDRIITVYFGSQFSEAA
                     LGLRLLVPGALCYALARVLWPVIQAGGEAMSLIRVMLLTVMVDAGLCAILIPAGGAAG
                     AACATSLSFALVAGGYLWILRRRNVSVFEGLALSRLVGLVVMTGIAMAGLSALVATPM
                     LSLLVGIAVGVFLYWGGVFSLGIVQVDELESLVQSLPGTFRKAGESVLRMVAPLLLRL
                     KAAASN"
     gene            4688..5572
                     /locus_tag="PK063_17920"
     CDS             4688..5572
                     /locus_tag="PK063_17920"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF025025.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HMZ98982.1"
                     /translation="MIPTLGRETLALCQEGLSKQTRLPDEVIVVLDRDRRGVAWGRNE
                     GIARSTGDLIAFVDDDAVPPQDWLERLVTAIDHYDAAVAGGTFKETDPLLDAIRRLNS
                     LPTVEQLDPGGLVGNAGNILFRRDCLLKCEREDGYVFNPLFTGAGEDWELIWRLRKRG
                     AKMVFVPNPVTHLRRATGLQHLRHSFHRGAGIAILFRVMRRDSSGVVPQDSLLWGEGG
                     KKTKPRWLKAIWVKMLGPFEWQKFQRKRHFCLFWLGEKCQAAGFFWEMCRKRSMTHID
                     RKTKPMVQAVSSRVESKS"
BASE COUNT         1015 a         1549 c         1817 g         1264 t
ORIGIN      
        1 gcaatcagcg ccggactgga gcattgccgc ggacgtgtcg tcagtattat ggatgccgat
       61 ctccaggatc ctcccgaagt ccttcacacc tttttggcca agtggcagga agggtgggaa
      121 gtcgtctatg cggtgcgaac cgagcggaag gaatggtggg gaaaacgctt agcctacgcg
      181 ggattctacc gcttgctgca acgggtcgcc aacatcgaga ttccgttgga tgccggagat
      241 ttttgcgtca tggaccgcaa agtcgtcgac ctgctcgtgc gcatgcctga acggaatcga
      301 tttgtcaggg gcatccgcag ctgggtcgga ttcaaacagg tcggcgtgcc gtatgagcgc
      361 caggcgcgcc atgccgggac gcccaagtac acgcttcgga agctgatcta tctggcgctc
      421 gacgggttgg tctcattcag ccacatgccg ttgcgcatca tcacgttgct gggctttacc
      481 gtttcgctgc tgtccttcct cgtggcgctg ttttatctca tcaagaaatt caccatcggg
      541 gtcggggtgg ccgggttcac cacgctggtc gtctcaattt tcttcctcgc ggggatacag
      601 ctcatgacga tcggcgtcat cggggaatac atcggacgca tatccgatga agtgaaacac
      661 cggccgctgt acgtcgcccg ccgtgtgacc aggagataat caccattcgc attctcatgt
      721 tcgataacga gttccctccc ctcgggggcg gcaccggcgt cgtcaatctc catttgctgg
      781 aggagatggc cttgcggccc gatgtcacgg tggacctcgt gacgtcctcg cgaaccaagg
      841 cgcgatacga aaccgaagcc tttgccgatc gcattacgat ctacaaggtg ccggtcgata
      901 atcgcaacat ccaccacgcc accaatcgtg aattgctgcg gtacagttgg cggggattgc
      961 gtctcgcacg gcaactagcg tccgaacatc agtatgatgt gagcttcgcc tttgcaggtg
     1021 tgccggccgg tgccatcagt tacctcttgc gtctcacgca tggactgccc tacgtcttgt
     1081 cgttacaggg gcccgatgtg ccggggttcg aggcgcgata caactacctc tacccggtgt
     1141 tgacgccgtt catcacacag atctggcgtc gagcgggtgt ggtgacagcc atcagcgcgg
     1201 aacaggtggc gttggcgcac cgcacgatac cggatctgcc ccttatcacg attcccaacg
     1261 gggtcgatac gaacgcgttt gtcccggcca cgagaaattc gagacggccg ttcaccatga
     1321 tttgtgtcgc tcgattgatt gagcgcaaag ggcaacatca tctgctacag gccttcgcca
     1381 acttgcgagc agcaaaccat gaaccgatgg cactgatctt cgtcgggacc ggggatgccg
     1441 agccgcagtt gcgagaattg gcggcgaagt tacaagtggc ggaggcggtg acgttcaagg
     1501 gctttgtgcc gcgcgagaac atgcctcctg tctatcacga cgccgatgtg ttcgtgttgc
     1561 cgtctcagca tgaaggcatg tcgatcgccc tcttggaagc gatggcctcc gggctcccgg
     1621 tgatcgtgac cgatacggga ggcactgcgg aattggtgac gcagggagcc aacggtgaga
     1681 tcgtgccatg ggatgatgtt gaggcactca cgaccgcgtt gcagcggctg ctgaacgctg
     1741 ctgagcagcg ccggcgcatg ggcgacgaaa gtcgtcgtcg tgcgctcgca ttcggatggc
     1801 ccacgctcgc cgcccgctac cttgagttgt gcgcgagggt tatggttccg tccgccgaaa
     1861 gccgagccaa ggatgcccga agtgcgaaaa acgtggctcg cgattggacc agggagctcc
     1921 ggggatgagg aaaatgcctc atgtgtgcat tctgaccagt cagtattttg attggggaat
     1981 ttatggaggc ttcggcagca tgtcgcggaa gctggccgaa agcctggtgc gtgccggcca
     2041 tcgggtcagc gtgatcgtgc ccggtcgtca gggccaacag cccacagaaa ccatcggcgg
     2101 ggtggagatt cgcagcttct cgccgcgcaa tgtcatggat gcctgtcgcc tcattcgcga
     2161 atcccgcgcg gacatttttc attcccagga tcctacggtc ctgacctacc tggcgcaacg
     2221 cattcacccg cgccgcgcgc atctggtgac gagccgggat ccgcgggaac tgagcgactg
     2281 gtgggtggag tttctgtatg ccactccgat gcgccgtctg ctgacgcccc tgaactattt
     2341 cacagaatca gggtttctcg tcaggcaagc ggtgcggcgg gccgatgcgg tgtattgtcc
     2401 ggcccatttt ctcaaggaga aggtcaagcg tctgtatggg ctcaagcagt tgccgacgct
     2461 gctccccaat ctcattgacg tgccctcggc gctccctcga aaaagcgagc ggccgacgat
     2521 cacctttatt gcccgttggg acaaacgcaa gcgcccctgg ctgtttttgg aactggctgc
     2581 gcagttccca gactatcggt tcgtggccgt gggcaaaggg agcgcttccg ccgaaaccgg
     2641 atttgacgcc gagttgcgac agcgattccg caacgtgccc aaccttgaaa tgccgggcct
     2701 gatcaatcga tttcatgagc cggagcgaat gcaccaaatt ttgtcggaca cctgggtctt
     2761 cgtcagcacg gcggtgcgcg aaggccttcc attaacgttc ctggaagcgg cggcctatgg
     2821 gtgtcccatc atcagccgcg tggatcccga ccagttcgcg acccggtttg gaaagcaggt
     2881 gcacgatgac gactatgccg ccgcgctgca gagcctgctc gccgaggcgc cgctggagaa
     2941 gggccgggcg gcctatcact atgtgcggga cacctacgaa acctccagag cgttgattgc
     3001 ccatcaagag caatatgcgc gttttgcggc ataagcgtct gtgaagggcg tgtatacgga
     3061 cttcggaaca gcggagtgtt cgatgttgaa gagccatgtc ggcgaaagcg gtttctaaag
     3121 gaattctctc cgtcggcggg tggtcgatgg ccaagctggc cacgtcagcc gtcgtcctgc
     3181 ctattctcgc gcgatttctc ggcatcgaag gatatggtca gtacgcttat tacctggcgg
     3241 tgctcttgct cgcctcgcaa tttgccaatg tgggcatgat gcaaacgatg accaggcgca
     3301 tcgccgagcg gcctgacgat gcagcatggt gccggggggt cgcgcgctcc ggcgcgctca
     3361 tcaatggcac gggagtcgta tttgtcgggc ttgcggccgg agtgttgatc tggggcacgg
     3421 cgtcgcacga gacagcgcgc gtgccgattg cgttggccgt ggtgggcgtc ctcgtatttg
     3481 accaggtctg gttttatgcg cgcggcgtgt tgcacggttt acgacatgaa gaacgcgcgg
     3541 cggtgcccgg catcatgggc gtcctgatgg caggaagttt cggcattatc gcggcggtca
     3601 ccgggatggg cgtggttggc gtcttggtcg gtctgctggt ggcggatatc tttgtggcag
     3661 gcgcctgtct gagagcggtg atggtggcat tgaacggcct cgggcttccg gcgtctcagg
     3721 gacctcccgc tttgccgacg ggagccgtgc ttcgattcgg attgtcggcc atgatttttt
     3781 ccgtgctcaa catggcgctc tgctcactgg acatcattct cgtccgacat ttggctgggg
     3841 aagctcaggc gggcctctac gcggcggcgg tgcagtggtc ccaattcgtc tggttcattc
     3901 ccattgcggt cgaaggagtg atgctgcaag cgaccgctcg gctgtgggct gaacagcggg
     3961 tagaggctgt gaccagcctg gtgagtcgtc tcgtacgcta cgtcatgctg ggcacggtct
     4021 ttctgctgat cgtggtgttt gtgttgggcg accggattat cacggtgtac tttggctccc
     4081 aattttcaga ggctgccctg gggttgcgtc tgctggtgcc cggcgcgttg tgttatgcct
     4141 tggcccgagt gctgtggccg gtcattcaag ccggcggtga ggcaatgtcc ctgatccggg
     4201 tcatgctcct gacggtcatg gtggatgccg gactctgcgc gatcctgatt cccgccggtg
     4261 gtgcagccgg cgcagcttgt gcgacgtccc tctcctttgc gctggtggcg ggcggctatc
     4321 tctggatatt acggcggcgg aacgtcagcg tcttcgaggg gctagcgctg tcgcgattag
     4381 tggggcttgt cgtcatgacc ggtatcgcaa tggccgggct ctccgcactc gtcgctacgc
     4441 cgatgctgtc tcttctggtg ggcattgccg ttggagtctt tctgtattgg gggggcgtct
     4501 tcagccttgg catcgtgcag gtggacgaac tggaatcgct cgtgcagagt ctgccgggca
     4561 cgtttcggaa ggcaggagag tctgtgcttc gaatggtggc tccgttgtta ttgcggttga
     4621 aagctgcggc atccaactag gagggggaac gctgaaactc catactgatc agcacaagat
     4681 ctctgtcgtg attcctactc tcgggcggga gacgctcgcg ttgtgccagg aggggctttc
     4741 gaaacagact cggttgccgg atgaagtcat cgttgttctc gaccgcgatc gccgcggggt
     4801 cgcgtgggga cgaaacgagg gcattgcccg gtctacgggc gacctgatcg cgttcgtcga
     4861 cgacgacgcc gttccgccac aagactggct ggaacggttg gtaaccgcca tcgatcacta
     4921 cgatgctgcc gtcgccggtg gcacgttcaa agaaaccgat ccgctcctgg atgccattcg
     4981 tcgtctcaat tcgcttccga cggttgaaca gctcgatccg ggaggattgg taggtaacgc
     5041 gggaaacatt ctcttccggc gtgattgcct cctgaaatgc gagcgagaag atgggtatgt
     5101 cttcaatccg ctcttcaccg gcgcaggcga ggattgggaa ttgatttggc ggctgcgcaa
     5161 gcggggcgcc aagatggtgt ttgttcccaa tcccgtgacc catctgcggc gggcgacagg
     5221 actgcaacat ctgcgacatt cctttcatcg aggcgcggga attgcgattt tattccgggt
     5281 catgcgtagg gattccagcg gagtggtgcc gcaggacagt ctgttgtggg gcgagggtgg
     5341 aaagaaaacc aagccgcgtt ggctgaaggc catctgggta aaaatgttgg ggccgttcga
     5401 atggcagaag tttcagcgta aacgacattt ttgtctcttt tggctgggag aaaaatgtca
     5461 ggccgccggg tttttctggg agatgtgccg gaaaaggtcc atgactcaca ttgaccgtaa
     5521 gacgaaacct atggtgcaag cggtttcttc cagggtggag agcaaatcat gagcgacgtg
     5581 cagttacgca cgaaggcgtg gttcggtgat gagccgctat cgatcaattt tccgcctgcg
     5641 tggaa
//
LOCUS       DAOQPD010000129         5359 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_9311_length_5359_cov_23.598228, whole genome shotgun sequence.
ACCESSION   DAOQPD010000129 DAOQPD010000000
VERSION     DAOQPD010000129.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 5359)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5359)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5359
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_9311_length_5359_cov_23.598228"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..3474)
                     /locus_tag="PK063_17925"
     CDS             complement(<1..3474)
                     /locus_tag="PK063_17925"
                     /inference="COORDINATES: protein motif:HMM:NF038336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STY4851/ECs_5259 family protein"
                     /protein_id="HMZ98983.1"
                     /translation="MTNVRFGVRGVHPIQQWKSSFLKQRGFDESTGRPLYTYRVTSEE
                     FSDLETTMRESLRLWLTVGTLGNIVRRFACFPPLFVLYAAEWWRRNYDGTGFAWEPIV
                     RALGASAETWSQAERSECVEKGLQGWRLRLSNSHGLRYLGSIAFQGGLPMRLLGSAQG
                     SIGGILKRALKLAGGGRTDAAEILEWIKSLAHFLPNSYRQNEVFVLLTEVVLTVLRLK
                     QQANLTGGADVLARLDQAVKGWRDEFPLPIDDHQAIELFKLAIGVPPGQQLHRSQAIL
                     VERWLDISDQGSFQLRSEIVLPEFLDSAPLARLFGIEPEKLSRALTLRFPRGEQAVDV
                     SLRRLAGQDRYRVERRTLDRRGDLAIAEHTMLLLIATGEARHTEIARGEALDPELPWI
                     FEQGDDSANPCRLIRQGSGAIAGFEGILCIPQDWEPRPDDGASVDCKGQLSGGTRRVW
                     TIRGGIRIDACDGLHYRVRCGQAAATEDRFELRGQRYWDLFDHPAVAFRGVPRLYQVS
                     ENGLERLAQGTLAWRVPGGQFTQRPEEISGPVSAIWPAQGETRWRTRVVLLPAQASMS
                     VEPGADPSSGALRFANWALLTVDCDTPGVSSQTRINGASVVLDLKFQGEGYPPEWCSV
                     NVVWRGNPNIVRLRVPFPAKGVRTIAANGTQLEDGALLAVGRVCGTRMVGFLGSGAHQ
                     ATLTLGLHRGNHAHPVSKVEHTIKAAVGGSRVEIRLVDYVNDVQRMLADADTLDAYVS
                     VRLRLYGGESSTLRVARYEFELKRLAMMSQLGLAQEQLRSFSVEDIARLPVVALRLDA
                     PGEEPIRLAPVCSEGVPTGNWLFPSVDLSPGAWLIHAGAGSQAAFRPMLWPVLPPVDV
                     PRETQDVEKVVEVEVSLTIALVIPTERQRLDALDAVIAALAQDFTSDGWRLVEQLAVQ
                     LGHLPLSTLDLWRCFAQSVTGLAALAVRMGGLPAGFAERFPIELPAAWEMIPLTAWVQ
                     AMRALMAQGTSWYGPEAGSIVVSEYLDRRVQALASACPSLRVLLEVARGTATAKINQD
                     LRAAQNPGMDGFFAGQLFNGENSRVQHLLRNNADRQWPGGFAAEVTDGRQHGARPYFC
                     PINHGFHDSVINLPILLALTRNTTMDLHVDLSQHPNLIRKVREVQSFDPEWFAEAFDL
                     TVARCLATGRID"
     gene            complement(4194..5186)
                     /locus_tag="PK063_17930"
     CDS             complement(4194..5186)
                     /locus_tag="PK063_17930"
                     /inference="COORDINATES: protein motif:HMM:NF023168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HMZ98984.1"
                     /translation="MARTSAVEYERVAEACSSLFLEGKSPSFESVYELIGRKGGAKVV
                     QGMIADWRKEMANRFMAGRTNPDLPEALITEADKVLTVVWRLALEKSDAAYADERSRL
                     DQARIDMAAAVTQAQERAAEFEREALSLQGERQALQARLQGSQAEIEDLRQRLADTTT
                     LLRARDEQIGQMREDGARLASTIESERRNHEAELLAERDRHEQAVNAERQRAHESVER
                     EREIAAGERQYLMRQTDEIRQAAKANEAVLKEQLQEARVFAESFQARAGRAESEAAFW
                     RGKAEAAAEESGRWQRSAEEAVGKIEGFQIRIRTLERERATLAAKHTPQKNDGY"
     gene            complement(5173..>5359)
                     /locus_tag="PK063_17935"
     CDS             complement(5173..>5359)
                     /locus_tag="PK063_17935"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98985.1"
                     /translation="RRRDMDTPQAQIIEQEIHDLSGLLCDLYRRVAENAPERAGEIAG
                     ALQANARQFAEIPSGTH"
BASE COUNT         1044 a         1700 c         1535 g         1080 t
ORIGIN      
        1 gtcaattcgt cctgtggcga gacagcgagc tacggtcaag tcaaaagcct cggcgaacca
       61 ttccggatcg aatgactgaa cttctcgtac cttcctgatg aggtttgggt gttggctcaa
      121 atcaacatgc aggtccatcg tcgtattgcg tgtgagtgcc aacagaatgg gcaggttgat
      181 taccgagtca tgaaacccgt ggttgatcgg acagaaatac ggcctagcgc cgtgctgcct
      241 gccgtcggta acttccgccg cgaatccacc gggccactgc cggtcagcgt tgttacgcag
      301 caggtgctga acccttgagt tttcgccgtt gaatagctgc ccggcaaaga agccgtccat
      361 tcctgggttt tgggcggccc tcaggtcctg gttgattttc gcggtcgccg tcccgcgcgc
      421 cacttccagc aacacgcgaa gtgatgggca ggcggatgcc aaggcctgca ctcgccgatc
      481 aagatattcc gagacaacga tggagccagc ctcaggtccg taccaggacg tgccctgcgc
      541 catgagtgcg cgcattgcct gaacccatgc ggtcaaggga atcatttccc aggcagcagg
      601 cagctcgatg ggaaatcgtt cggcgaatcc agcgggcaag ccacccatgc gcactgcaag
      661 tgctgccagg cccgtcacgg actgggcgaa gcaacgccaa aggtcgagag tagacaaagg
      721 caggtggccc agttgcaccg caagctgctc aaccaggcgc caaccgtcgc tggtgaagtc
      781 ctgcgccaac gcggcaatca ccgcatccag ggcgtccaga cgctgtcgtt ctgtcggaat
      841 gacaagcgct atggtcaggc tgacttcaac ctcaacgact ttctccacgt cttgcgtctc
      901 tcgcggcaca tcaaccggcg gcagaacggg ccataacatc gggcggaaag ccgcttgaga
      961 cccggcaccc gcatggatca gccaggctcc gggcgagaga tcgacagatg ggaatagcca
     1021 gttgccggta gggacgccct cggaacaaac aggagccaaa cgaatgggct cttccccggg
     1081 ggcgtcgagc cgaagtgcga ctaccggcaa tcgcgcgata tcctccaccg agaaactgcg
     1141 gagctgttcc tgggccaagc caagctgcga catcattgcc agccgtttga gttcgaactc
     1201 gtaacgggcc actcgcagcg tcgacgattc cccaccgtac aagcgtagtc ggacgcttac
     1261 ataggcatcg agggtgtcgg cgtcggcgag cattctctga acgtcgttca cgtagtcgac
     1321 caggcgaatc tcgacgcgac tcccaccgac agcagccttg atcgtgtgct ccactttgct
     1381 gaccggatga gcgtgatttc cgcgatgaag cccaagcgtc agcgtcgcct ggtgggctcc
     1441 agacccgaga aaacccacca ttcgggtgcc gcatacccgg ccgacggcga gcaaggcgcc
     1501 atcttcgagc tgcgtgccat tggcggcgat ggtacgtacc cccttggccg ggaacggaac
     1561 cctcagtcgg acgatattgg ggttgccacg ccacaccacg ttgaccgagc accactcggg
     1621 tggatagcct tcgccctgga acttcagatc aagcacgacg ctcgcgccgt tgatgcgcgt
     1681 ctgcgacgag acgcccggcg tgtcgcaatc caccgtcaac agagcccagt tggcgaagcg
     1741 tagtgcgccg ctcgacggat cagcaccggg ctcgaccgac atgctcgctt gcgcaggcag
     1801 gaggacgacg cgcgtacgcc atctggtttc cccttgcgct ggccagatcg cgctcaccgg
     1861 accggagatt tcctcggggc gctgcgtaaa ctgtcccccc ggcactcgcc aggcgagcgt
     1921 gccttgagcc aatctttcca gcccgttttc ggacacctgg tacagccttg gcacgccacg
     1981 aaacgcaact gcggggtgat caaacagatc ccagtaccgc tgcccgcgaa gttcaaaccg
     2041 atcctcggtc gccgcagcct gcccgcacct cacccggtag tgcagtccgt cgcaagcatc
     2101 gatccgaatg ccaccgcgga tcgtccatac ccttcgagtg cctcccgata gctggccctt
     2161 gcaatccacg gatgcgccgt cgtcgggccg cggctcccaa tcctgcggaa tgcacaggat
     2221 tccctcaaac ccggcgatgg ccccggaacc ttggcgaatc agtcgacaag ggttcgccga
     2281 atcatcgccc tgctcgaata tccagggcaa ctcgggatca agcgcttcgc cgcgggcaat
     2341 ttccgtgtgg cgcgcctccc cggttgcgat caggagcaac atcgtatgtt cggcaattgc
     2401 gagatctccg cgcctgtcca gagtgcgccg ttcgacacgg tagcgatcct ggccggccag
     2461 cctgcgcagg gagacatcca ccgcttgttc gccacgcgga aatcgcaagg tcagggcgcg
     2521 gctcagcttc tcaggctcga ttccaaaaag ccgcgccagt ggtgccgagt ccaggaactc
     2581 tggcagcacg atttccgatc ggagctgaaa agagccttga tccgagatgt ccagccatcg
     2641 ctcaacaagg atcgcctgac ttctgtgcaa ttgctggcct ggagggacac cgatagccag
     2701 cttgaacaac tcgatcgcct gatgatcatc aatcggcaac gggaactcgt ctctccatcc
     2761 cttgacggct tggtcaagtc gggcaagtac atccgcgcca ccggtcagat ttgcctgttg
     2821 tttcaggcgc aggacggtaa ggacaacctc ggtgagcagc acgaagacct cgttctgccg
     2881 ataggaattg ggcaagaaat gggcaaggct cttgatccat tcaaggatct ccgctgcgtc
     2941 cgttctgcca cctcccgcaa gcttgagcgc ccgcttcagt atcccgccga tggagccctg
     3001 tgcgcttccc agaagccgca tcgggaggcc gccctggaag gcgatacttc ccaggtagcg
     3061 cagtccgtgc gagttcgaca agcgcagccg ccagccttgc agaccctttt cgacacattc
     3121 actgcgctca gcctgactcc acgtttcagc ggaagcgccg agcgcacgga caattggttc
     3181 ccatgcgaat ccagttccat catagttgcg gcgccaccat tccgccgcat acagcacgaa
     3241 caagggtgga aagcaggcaa acctgcgaac gatgttaccg agcgtaccga ccgtaagcca
     3301 caagcggagg ctctcccgca ttgtggtttc gagatccgaa aattcctcgc ttgttacccg
     3361 gtaggtatac agcggtcgac cggtcgactc gtcgaatcct cgctgtttca agaagctgct
     3421 cttccactgc tgaattggat gcactccacg cactccaaaa cggacattcg tcattcgtca
     3481 agacaacttc tcttgcaggc tctccgtgct tgatgcctcg gcgatcgttt ttccggaaac
     3541 ctagcggtcg cccttcagga tttgtgtatt ccccatccat ccgcatgggg atccaagggg
     3601 caacgctcgt caattaacaa cgtagggcga cagcatacgc gcagtatcaa gccgcgcgag
     3661 caataggcct acccctcttc gtcggcattg cagtaagcgg agaatccggc acgacagcat
     3721 ggatccggcc catctagcga ggtcttgccg ccaagggcag tgcagtggcc ttcgccgatt
     3781 ccgtgcgcat tcgtgtattc ccgtagccag aatggacatc gatcagcgcg aggtggaatc
     3841 gtagattgtt cgccgttgtc gacgtttgtc ataatgacct ccctaaaatc aacaagtgga
     3901 atgctaagca gtcatcaaaa tgtctttcgt gattccatgc acggttcccg aggctaggag
     3961 cgtctgacga tccgaagact taagcgctgc tgaaaaagtc ttccgacatt ccagtagcga
     4021 cactacgagg gattccgtcg tgtgaatgtc ggagaactta tctgagaccg cttatctgcg
     4081 agcgcttaac ggtaatgact tagaccttgt tgctggtaaa cgcggccttc gtcatagaca
     4141 tagtttgcct ttgtcgtcga aacacgttac tcgccatcgc ccatgaacag cgctcaataa
     4201 ccatcatttt tctgaggagt atgcttcgct gccagtgtgg cacgctcgcg ttctaatgtc
     4261 cgtatgcgaa tctgaaatcc ttcgatcttg ccgaccgctt cttctgcaga ccgctgccag
     4321 cggccggact cttccgccgc cgcttcggcc ttgccgcgcc agaacgccgc ttcgctttcc
     4381 gcccgaccgg ctcgagcctg gaaactctcg gcgaagactc tggcctcctg gagttgttcc
     4441 ttgaggacgg cttcgttcgc ctttgcggct tgccggatct catcggtctg gcgcatcaag
     4501 tactggcgtt cgccggcggc aatctcccgc tcgcgctcga ccgattcgtg cgcccgctgc
     4561 cgttcggcgt tcactgcttg ttcgtgtcgg tcacgctcgg cgaggagttc ggcttcgtga
     4621 ttgcggcgct cactctcgat ggtgctggca agccgggcgc catcttcgcg catctggccg
     4681 atctgctcgt cacgggcgcg gaggagggta gtggtgtcgg ccaggcgttg ccgcaagtct
     4741 tcgatctcgg cctggcttcc ctggagtctc gcctgaaggg cttgccgctc tccctgcaag
     4801 gaaagggctt cgcgctcgaa ctcggcagcg cgttcctggg cttgcgtcac cgctgcagcc
     4861 atgtcgatgc gagcctggtc gagtctgctt cgttcatcgg cgtacgcggc atcggacttt
     4921 tccagcgcca ggcgccagac gacggtgagc accttgtcgg cctcggtgat caacgcttcc
     4981 gggagatcgg ggttggtacg gccagccatg aatcggttgg ccatctcttt acgccagtcg
     5041 gcaatcatcc cctggacgac cttggcgccg cccttgcggc caatcagctc gtagaccgat
     5101 tcgaacgacg gactcttgcc ttcgagaaag agactggagc aggcctcggc gacccgctcg
     5161 tactcgactg cgctagtgcg tgccactggg gatctcggca aactgccggg cgttggcctg
     5221 cagcgccccg gcgatctcgc cagcacgctc cggtgcattc tcggccacgc gccggtacag
     5281 atcgcacagc aagccgctga ggtcgtggat ttcctgctcg atgatctgtg cctgcggcgt
     5341 atccatatcc cgtctcctt
//
LOCUS       DAOQPD010000130         5199 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_9784_length_5199_cov_22.502722, whole genome shotgun sequence.
ACCESSION   DAOQPD010000130 DAOQPD010000000
VERSION     DAOQPD010000130.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 5199)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5199)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5199
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_9784_length_5199_cov_22.502722"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1025
                     /locus_tag="PK063_17940"
     CDS             <1..1025
                     /locus_tag="PK063_17940"
                     /inference="COORDINATES: protein motif:HMM:NF012264.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="c-type cytochrome"
                     /protein_id="HMZ98986.1"
                     /translation="VVSMRAWRRIRVFGAVVGVVGLSGLIGAGCSMMQSEQAAKGKKL
                     YAHYCMHCHGETGKQNEGFNWSSMSDPKPKDLSNKSEMGTFKDEDIFATISRDMKDTS
                     PNGDKIGDDEFAVPTMPTFKYTLSEEEIWGIVGYVRSLHGKKLEFNVEGRKKELQEAK
                     QSAEQKYKEAERVEQEAEKKASDEADKKGVEVDDNAYAKEMQAMGQAKKELDQATAAL
                     ANFTTRPGKGVNIARPDLNMKPDAAAKLVEVGKQIYVTKYGCNGCHKIGEDGGKVGPA
                     LDRAGYRLNPTWVYRWLRNPQAMKPDTRMPSLGLNDADAKAVALYLKTLRAPKPDKPL
                     GKVGEE"
     gene            complement(1027..>1593)
                     /locus_tag="PK063_17945"
     CDS             complement(1027..>1593)
                     /locus_tag="PK063_17945"
                     /inference="COORDINATES: protein motif:HMM:NF013226.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybenzoate octaprenyltransferase"
                     /protein_id="HMZ98987.1"
                     /translation="VAAGLVATLNWLTILLSPIALFLAAIYPFCKRWIQIPQAVLGIA
                     FGWGTIMAWAASCDSLAPAAWWLFAATTCWAVAYDTIYALQDREDDRRIGVKSSALLF
                     GTAVPTAVGLFLLGMIVCLIIAGQLAGLGMGYYVALTLLTGVFLWQARRLRFPVTPLQ
                     AFSMFQQHVVAGLVILIALWISASHDLP"
     assembly_gap    1594..1693
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            1949..3847
                     /locus_tag="PK063_17950"
     CDS             1949..3847
                     /locus_tag="PK063_17950"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98988.1"
                     /translation="MAAVLVSSGCQYFSPRHVSTNYNLPLSVLLRLDPSIGAATLDYR
                     DACGQSVTLPIHEPLAAELKKRMEQVFERVVIQPGPPNEAIDGVVDVAIGLRQVDLFV
                     ARKANKSYPATVTLGLDVAYTEAQGTLLHSKKLQSVTTGEVDARAETCDISGVDKVAK
                     DVISTVVEGVAQQLGTSTKIRELAQSRKAQRGTTGKAASAGQAAPPSPPAPPLSNVPA
                     VPAPVAAATEGTSAPPVSSTGTTHLSFRTILRDQNQNHVLEQNERFSVEFEVRNDGPT
                     PADAVAVDLSGHPAIIASVKTPVSVGLLQPGEIRRVTVEGTVGKVAEAEQAELICTLQ
                     AAANVALPSAKKFFVAIRPDATDATEVVSVDVDQLPSKKGKPVQTHAVAIAIGVGAFR
                     DPAMPTMKLATHDAEIMSGYFTSVMGISPQKVKVVLDAKGLKDDWIEVFEQWLPKQVD
                     PQTTAYVYVAGRAMVDHETGAVSLLPYDATLSGSSRAFSLARLQRALTNAPVKQAVVM
                     LDLSLEPSSGSDPARVAQPRWISPEANGEQERVMLMVGNATVQEAQAYQPGQHGLFTY
                     FLLKGLRGAADLDKNGSVLTGELCAYVQRQVTAVGRSTSGDTQQPLCLPDANGASPLR
                     QLRLSKLP"
     gene            3948..5108
                     /locus_tag="PK063_17955"
     CDS             3948..5108
                     /locus_tag="PK063_17955"
                     /inference="COORDINATES: protein motif:HMM:NF024863.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDSL-type esterase/lipase family protein"
                     /protein_id="HMZ98989.1"
                     /translation="MRIRSLANLLVITVLLLISVGLSVALLEFAAGYLYDRAGLANGK
                     RMVDLYLGRTPEMRVGAKEAEKASITPHPYLLFVHTPNMTVDGYQQTNSLGYRNKEFT
                     VEKPADTIRILVVGGSTTFMWPYIKNPADTWVARLEAKLQAISSKQVQVINAGVNYGT
                     SAEALAGYVFRHRFLQPDIVIYHGGGNDVLPLFFDHYNPEYTHFRSAGGSKPRPGEKR
                     LLEHSHTARYLYARWLEPVGSVVVTQPFWEVDPLVALERVRQQAPIGFERNVDSLITL
                     SKSSGADVVLFGFLQAKKQYLSKNAPAFKGYEDALVLGLEKNYEVLARAGSRHHVPFV
                     IPAQDRFQDEWFQDNCHLTPEGEEVKAQIMFEELKTHPQFFSARNPTPPVTH"
BASE COUNT         1179 a         1395 c         1532 g          993 t
ORIGIN      
        1 gggtcgtgag catgagggcg tggcgaagaa tacgcgtctt tggagcagtc gtcggagtcg
       61 tgggcctctc gggcctcatc ggtgccggtt gttcgatgat gcagagtgaa caggccgcca
      121 agggcaagaa gctctacgcg cactattgca tgcactgcca cggtgaaacc ggaaagcaga
      181 atgaagggtt taactggtcc tctatgagtg acccgaaacc aaaggatctg tccaataagt
      241 ccgaaatggg cacattcaag gacgaagata ttttcgccac gatctcccgg gacatgaagg
      301 atacgagccc gaacggcgac aagatcggcg acgacgagtt tgcggtgccg accatgccga
      361 ccttcaaata cacgctgtcg gaagaagaga tttggggcat cgtcggctac gtgcggtcat
      421 tgcacggcaa aaaattggaa tttaacgtcg agggtcgtaa gaaagagctt caagaggcca
      481 agcaatctgc cgagcaaaag tataaagagg cggaacgtgt agagcaggag gccgagaaga
      541 aggccagcga cgaagccgac aagaagggcg tggaagtcga cgataatgcc tatgccaaag
      601 aaatgcaggc gatggggcag gccaaaaagg agctggatca agccacagcc gcactggcca
      661 atttcacaac ccgcccaggc aaaggcgtga acattgcgcg gccagacttg aacatgaagc
      721 cggacgccgc cgcgaaactc gtcgaagtcg gcaagcaaat ctatgtcacc aagtatggct
      781 gcaacggatg ccataagatc ggagaagacg gtggaaaggt cggtcctgct ctggatcggg
      841 caggctatcg attgaatccg acctgggtgt accggtggct gcgtaacccg caagccatga
      901 agccggatac gcgcatgccc agcttgggtc tgaacgacgc cgacgccaaa gcggtggcgc
      961 tctatctgaa aacactccgt gctccgaaac ccgacaagcc gctcggtaag gtcggagagg
     1021 aatagcttag ggcaagtcgt gtgacgcgct aatccacaac gcgatcagaa tcacgagacc
     1081 agccacgaca tgctgctgaa acatgctgaa ggcttgaagc ggcgtcacgg gaaaccgtag
     1141 gcgccgcgct tgccagagaa agactcccgt cagcagcgtt aaggccacat agtatcccat
     1201 ccctagacca gccagctgtc ccgcgattat caggcagact atcattccca gcaaaaacag
     1261 gccgacggcg gtaggcacgg ctgttccaaa aagcagcgcc gaagacttta ctccgatgcg
     1321 gcgatcatct tcccggtcct gcagcgcata aatcgtatcg taggccactg cccagcaagt
     1381 cgtggcggca aacagccacc aggcagccgg cgcgagactg tcgcacgatg cggcccaggc
     1441 catgattgtt ccccatccga aggcgattcc caatacggcc tgcggaatct gaatccatcg
     1501 tttgcaaaat ggatagatcg cggccaggaa caaggcgata gggctgagta gtatcgtcaa
     1561 ccagttgagt gtggccacga ggcctgccgc tacnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1681 nnnnnnnnnn nnncccgact gattatccag gcggataaga tcggcgacgg cactccacgt
     1741 ccagggcggt gaggggcgtt gcattgaatc gttggaagag ctcacgcgtt ggaccataac
     1801 gaagcacaca gagcctgtca acgcgagtga ccggcggttg tcatgtcttc gccagattgg
     1861 gtataacaca agtattgtgc agcgattgat cggcggttgg atcaggtgtc gcattcggca
     1921 gtcctcccag tgtgctcttg cggcgctcat ggcggcagtg cttgtgtcat ccggctgcca
     1981 gtacttcagc ccgcgtcacg tgtccacgaa ttacaacctt cccttgagtg tgttgctgcg
     2041 tttggatccg agcatcggtg ccgcaacctt ggactatcgc gatgcttgcg gtcagtcggt
     2101 taccctgccg attcatgaac cattggcggc cgaactcaaa aaacggatgg agcaggtgtt
     2161 cgagcgggtg gtgatacaac cagggccgcc gaacgaggcg atcgatggtg tggtggatgt
     2221 cgcgatagga cttcggcagg tcgacttgtt cgtcgcccgc aaagccaata aatcctaccc
     2281 tgccacggtg acgctgggac tcgatgtggc gtacaccgag gcgcaaggca ctctgctgca
     2341 tagtaagaag ttacaaagcg tgaccacggg ggaagtcgat gcgcgggcgg agacctgtga
     2401 catcagtggc gtcgataagg tggccaagga tgtcatctcc acggttgtgg aaggtgtggc
     2461 ccaacagctc ggcacctcca caaaaatccg ggagctcgcc cagtcgagaa aagctcaacg
     2521 aggaacgacg ggcaaggccg cctcggcagg gcaggctgcc cctccctctc cgcctgctcc
     2581 gcctttgtcc aatgtgccgg ccgttccagc gccggtggca gctgcgactg aagggacctc
     2641 tgcaccgcca gtctcctcga ccggcacaac gcacctgtca ttccgcacca ttttgcgaga
     2701 ccagaaccaa aaccacgtcc tggagcagaa tgaacgcttc agcgtggaat tcgaagtcag
     2761 aaacgacggg ccaacgccgg ccgacgccgt tgcggtggat ctcagcgggc atcctgccat
     2821 tatcgcctca gtgaagacgc ctgtctccgt ggggctgttg cagccaggag aaattcggcg
     2881 cgtcacggta gagggcactg tcggtaaggt agcagaggcg gaacaggcag aattgatctg
     2941 caccctgcag gctgccgcga acgttgcgct tccgtcggca aaaaagtttt ttgtggccat
     3001 cagaccggat gcgaccgatg cgaccgaagt cgtctccgtg gatgtcgatc aactccccag
     3061 caaaaagggg aaaccggttc agacgcatgc cgtcgcgatt gcgatcggag tcggtgcgtt
     3121 tcgcgatccg gccatgccta cgatgaaact ggccacgcac gatgccgaaa tcatgagcgg
     3181 gtacttcacg tccgtgatgg gaatttcgcc gcagaaggtc aaagttgtgc tggatgccaa
     3241 gggactaaaa gacgattgga ttgaggtatt cgaacagtgg ttacccaagc aggtggaccc
     3301 gcagaccacg gcctacgtgt atgttgctgg acgagcaatg gtggatcatg agactggtgc
     3361 cgtatcgctg ctaccgtatg atgccacgct atccggctct tcccgcgcgt tctctctggc
     3421 ccggttgcag cgcgcactga cgaacgcgcc tgtcaaacaa gccgtcgtga tgttggatct
     3481 ctcactggag ccctcgtccg gttcggaccc tgcgcgcgtg gcccagccgc ggtggatttc
     3541 gccggaggcc aacggggagc aggagcgtgt gatgctgatg gtgggcaatg ccaccgtgca
     3601 ggaagctcag gcgtatcaac caggccaaca tggcctcttc acatattttc tcctcaaggg
     3661 acttcgcggc gcagctgatc tcgataaaaa cggatcagtg ctcaccggag aattgtgcgc
     3721 ctacgtgcag cgacaggtta cggccgttgg gcggtcgaca tcgggggata cccaacagcc
     3781 gctctgcctt ccggacgcca acggcgcgtc tccccttaga cagctccgtc ttagtaagct
     3841 gccctgacgg cgcgtcaccg gttccaatag tggtctagcg tactgaacga ttcattcgtg
     3901 gttcgtccgg tccttcgctc tctggttgct tgtgctcgcg gcacaccatg cgaatacgaa
     3961 gcctcgccaa tcttcttgtc atcacggtgc tgctgctcat cagcgttggc ctatccgttg
     4021 cgctgttgga atttgccgcg ggctatctct acgaccgcgc gggactggcg aatggaaagc
     4081 ggatggtgga tctctatcta ggccggacgc cagagatgcg tgtgggtgca aaagaagcgg
     4141 agaaggcctc gatcacgccg catccgtatc tgctgtttgt gcataccccc aacatgaccg
     4201 tagacgggta ccaacaaacg aattcactcg ggtatcgcaa taaagaattt acggtggaga
     4261 aaccggccga caccattcgg attctggttg tgggcgggtc caccacgttc atgtggccgt
     4321 acatcaaaaa tcctgccgac acatgggtgg cgcgcctgga agcgaagctc caagcgatat
     4381 caagcaaaca agtccaggtc atcaatgccg gagtcaacta tggcacgagt gcggaagcct
     4441 tagccgggta cgtgttccgg catcggtttc ttcagccgga catcgtgatt taccatggcg
     4501 gaggaaacga tgtgctgccg ttattttttg accattacaa ccctgagtat acgcatttca
     4561 gaagcgccgg tgggagtaag ccgagaccgg gagaaaagcg gctccttgag cacagccata
     4621 ccgccagata tctttatgcc aggtggcttg aaccggtcgg gtcggtggtg gtgacgcaac
     4681 cattttggga agtggacccg ctcgtcgcat tagaacgggt tcggcagcaa gccccgatcg
     4741 ggtttgagcg aaacgtggat tctctgatca ctctgagcaa gagttcaggg gcggatgtgg
     4801 tgctctttgg gtttttgcag gcgaagaaac aatatctgag taagaatgcc ccggcattta
     4861 aaggttatga agatgcgctc gtacttgggc tggagaaaaa ttatgaggtt ctagcacggg
     4921 ccgggagtcg gcatcacgtg ccctttgtca ttcctgctca ggatcgattc caggatgagt
     4981 ggtttcagga caattgccac ctgacaccgg aaggagaaga ggtcaaagcg cagatcatgt
     5041 tcgaggagct gaagacccat cctcaatttt tcagcgcaag gaacccaaca ccccccgtca
     5101 cacattgaca ggtgtttcac cgtctgagta atattgcgcc tcaccccgcc tggccggcgt
     5161 agctcagttg gcagagcagc ggtttcgtaa accgcaggt
//
LOCUS       DAOQPD010000131         5176 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_9846_length_5176_cov_17.256981, whole genome shotgun sequence.
ACCESSION   DAOQPD010000131 DAOQPD010000000
VERSION     DAOQPD010000131.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 5176)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5176)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5176
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_9846_length_5176_cov_17.256981"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..212
                     /locus_tag="PK063_17960"
     CDS             <1..212
                     /locus_tag="PK063_17960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98990.1"
                     /translation="IRNTEAQEKKAYPLARIMTIEDREEGLVILTTDAHLPRRIGEAL
                     KHSHHGHLDIQYDQDEDFIRITWTG"
     gene            278..829
                     /locus_tag="PK063_17965"
     CDS             278..829
                     /locus_tag="PK063_17965"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HMZ98991.1"
                     /translation="MGEQRRGWSLASGLLTGGILVLVAMLPIAKAEVQLLPGAAAELD
                     QATANAVLKTFQQAEEALRGRHVDGVMALYSEQYDYHGLHKKDMRKVWVDLLDEFQDL
                     ADVHHFSRMSKIGSGSKTIIEVTCTGSLTGLSKTGGLRVPIDSWYEEVHYMTWEDGQW
                     RIRGNVGDSPRFMPFGTSPHPLF"
     gene            1032..1889
                     /locus_tag="PK063_17970"
     CDS             1032..1889
                     /locus_tag="PK063_17970"
                     /inference="COORDINATES: protein motif:HMM:NF012791.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HMZ98992.1"
                     /translation="MRVLIALDWSEQAFAAVREVSYLYDLQEVVLVHGIDLGMFQYPI
                     VAEVSNMQGYDEFRKAMEAAGQQLLDHTSTLLPSQGVSTTRVCEFAKPASLILDKARD
                     MRAELIVIGGRGRSRVGEFVLGSVSHRVALHADCTTLIVKEREGPVKRVTVAIEGHED
                     AERIKAWLLAHPFKNPVDLTIVSVVRPIPATDPFNLFPLQDWTGIAVRSAEDLVKNLA
                     AAVMNHRYSVGTQVAVGDPTDILTERARSSDLLIIGSHGRKRLERFLLGSISHALLHQ
                     VPCPVLLVR"
     gene            1939..2301
                     /locus_tag="PK063_17975"
     CDS             1939..2301
                     /locus_tag="PK063_17975"
                     /inference="COORDINATES: protein motif:HMM:NF024834.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HMZ98993.1"
                     /translation="MKTFSILCALSLVILGSSWAAGQTNRGNPRDGQAIYEKNCLRCH
                     GEKLDGNGPEGQYLIVRPANFQSVNSRAKTDWELLITIANGALFSPMHGYRGKLTDQQ
                     MLDVLSYIRSVATPDFVS"
     gene            2458..>5176
                     /locus_tag="PK063_17980"
     CDS             2458..>5176
                     /locus_tag="PK063_17980"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HMZ98994.1"
                     /translation="MQRIRPRQMSPLRDEGPGSAHTILSDGTTALLRLAQPVDAEELQ
                     RFFSHLTPAATRHRFFSESAPPAEVIRALCDPSHPERSLTVIVLRRHDDTLRIIASGS
                     YHARGPHEAEVAMAVDDALHGHGLGTILLERLALLAIRQGFTKLWAITHADNLAMREV
                     FATSGFTMEEHLEGGDMEVELSLTPTDQSVRQSEWRERVATIASLHPLFHPRAVAVIG
                     ASRAPRSIGYRLLDALHHNRFEGRCYAINPHASTIAGVEAFPSVRHLPTPVDLAVIAV
                     PKEAVLSVVDECAAIGVRALVVITAGFAEVGAEGRRLQDQLLEKVRLHGMRMVGPNCF
                     GILNTDPAVRLNATFTSTFPCAGSIAMSSQSGALGLALVAASERLHLGLSTFVSVGNK
                     ADVSVNDLLQYWEQDTATNVILLYVESFGNPRRFAQIARRVSRNKPIVVLKAGRTSSG
                     KRAAGSHTAALAANDVAVEALFQQTGILRADTLEEMFALATGLSEQPLPKGRRIGILT
                     NAGGPAILCADACEAAGLEVPELSQATISRLSPFLPASASLRNPVDLIASATPEQYEQ
                     AIVALLTSEDIDALIILYIAVTATDVDPIAQGIARGIEAARAQQLVKKPVSIGWMVET
                     DRDRRFSLPHETIPTYSLPELPARVLGKVAGYVQWRDRPLGMVPDFDDLDISSIKTVC
                     RSVLATRGNGWLTVTETRAVLSSMGISLPPGGLATTAEEAATIAAQIGFPVAVKLASH
                     TLVHKTEVGGVHLNLSSKAEVRRAYDEIAARLAQDHTLDAMEGVLVQSMVTNGVEVMA
                     GMVQDPSFGPLIGFGLGGIHVEILGDVRFRITPLTELDAADLIRSIKGYRLLQGYRGH
                     APGDVDAIQELLLRLSRLVEEVPDIVELDLNPIFALPPGQGYRIVDARIR"
BASE COUNT         1043 a         1558 c         1558 g         1017 t
ORIGIN      
        1 ttatccgcaa taccgaggcc caggaaaaga aggcctatcc cctggctcgt attatgacga
       61 tcgaggatcg ggaggaaggt ctcgtcatcc tcaccaccga cgcccacctg ccccggcgca
      121 tcggtgaagc cttaaaacat tcgcaccatg gtcacttgga cattcagtat gaccaggatg
      181 aagactttat ccggatcacg tggaccggat agatgccttg aatgaacgga ttatgcaccg
      241 tgccagaagt gggcagatga atcacaacga gggaaccatg ggcgaacagc gtcgaggatg
      301 gagtctagct agcgggttgc tgaccggtgg aatcctggtt ctggtcgcta tgctgccgat
      361 cgccaaggca gaagtccaac tgctgcccgg cgcagccgct gagctcgatc aggcgacggc
      421 caacgcggtg ctgaaaacgt ttcagcaggc ggaagaggcg cttcgggggc gccatgtcga
      481 tggcgtgatg gcgttgtatt cggagcagta cgactatcac ggattgcaca agaaagacat
      541 gcgcaaagtc tgggtggatt tgctggatga atttcaggat ctcgccgatg tccatcactt
      601 ctcccgcatg agcaagatcg gctctggatc aaaaaccatc attgaggtca cctgcacggg
      661 cagcctgaca ggcctctcca aaaccggagg gctgcgcgtg ccgatcgaca gctggtatga
      721 ggaagtgcac tacatgactt gggaagacgg acagtggcgc atccggggca atgtcggcga
      781 ttcaccgcga ttcatgccct tcggcacgtc accgcatccg ttgttttagc ccgcatggtc
      841 atgacgatgc atcgagacat cgccgagtca cgttgcgagg aggggcgcgg aaacggaaga
      901 ggctgggggt acgcttggag tacgctgaga accagagggg cgagccaagc agccaaaggc
      961 ccgtcgcagc agtgactcgg cgagtgcagc agcagtgctc atgaaccatg cgggctagtg
     1021 aaaggagtcc tatgcgcgtc ctgatcgcac tcgattggtc ggaacaggcg ttcgcagccg
     1081 ttcgagaagt ctcgtacctg tacgatctgc aggaggtcgt cctcgtacat ggcatcgatc
     1141 tgggcatgtt tcaatatccg atcgtcgcgg aagtgagcaa catgcaaggc tacgacgagt
     1201 tccgcaaggc catggaagcg gctggtcaac aattgttgga tcatacctcc acgctcctgc
     1261 cctcccaagg cgtgtcaacc acgcgcgtct gcgaattcgc caaaccggcg tcgctgattc
     1321 tcgacaaggc gcgagacatg cgggcggagc tgatcgtgat cggagggcgt ggcagaagcc
     1381 gcgtcgggga attcgtcctg gggagcgtat cgcaccgtgt cgcgctgcac gcggattgta
     1441 cgaccttgat cgtgaaggaa cgcgagggcc cggtcaagcg agtgacggtg gcgatcgaag
     1501 gccatgagga cgccgagcgc atcaaagcct ggctgctcgc gcatcccttc aaaaatcctg
     1561 tcgatcttac gatcgtgagc gtcgtgcggc caatcccggc cacggatccg ttcaacctgt
     1621 ttcctctcca ggactggacc ggtatcgccg tacgatcggc tgaggacttg gtgaagaatc
     1681 tcgcagccgc tgtcatgaat catcggtact cggtcggcac acaagtggcc gtgggcgacc
     1741 cgactgatat tttgacagag cgcgcccggt cgtccgacct gttgatcatc gggtctcacg
     1801 ggaggaagcg actggaacgt ttcctcctgg ggagcatttc ccatgcgctc ttgcaccaag
     1861 ttccttgtcc cgtgttactg gtacgataag gtgatggccg tccggtggcg aaacgttgaa
     1921 ccataaagga gccagcgcat gaaaacgttc agcattctct gtgccctcag ccttgtgatt
     1981 ctcggaagtt cctgggccgc cggacagacc aaccggggca atccgcgcga cggacaggcc
     2041 atctacgaaa aaaattgcct gcgatgccat ggcgaaaagt tggacggcaa tgggccggag
     2101 ggtcagtatc tcatcgtccg cccggccaat tttcaatcgg tgaactcgcg cgccaagacc
     2161 gattgggaat tgttgatcac catcgcaaac ggcgcgttat tcagccccat gcacggctac
     2221 cgcgggaaac tgacggatca gcaaatgctg gacgtcttgt cctatatccg ctccgtcgcc
     2281 acgccggatt tcgtcagcta gccgggcagc cttctcggtg ggcgatgctc gactgacatt
     2341 ccccttgggc ggggcagcgg aattctggaa cggcgacttg caactgtgag gtcgcacggt
     2401 catgatcgga tccggcgtct tcatgcttct gaccgtggct cgacgcgctg gtagcccatg
     2461 caacgtattc gcccccgcca aatgtccccg ctgcgggacg aaggtcccgg ttcggcccac
     2521 accatcctca gcgatggtac gacggccctc ctccgcctgg ctcaaccggt cgatgcggag
     2581 gaactgcaac gtttcttctc ccacctaacc ccggccgcga cacggcatcg cttcttctcg
     2641 gaatccgctc cgcctgccga ggtcattcgc gcgctctgcg atccttcgca cccggaacgc
     2701 agcctgaccg tgatcgtcct gcgccggcac gacgatacgc tacgtatcat cgcatcaggc
     2761 tcttaccacg cgcgaggtcc gcatgaagcg gaagtggcaa tggccgtgga cgacgcgctc
     2821 catggacatg gtctcggcac cattcttctc gaacgcctgg cgctgttggc gatccggcaa
     2881 gggttcacca aactctgggc tatcacccat gccgacaatc tggcgatgcg cgaagtgttc
     2941 gcgacgtccg gcttcaccat ggaagaacat ctcgaaggcg gtgacatgga ggtcgagttg
     3001 tcactgaccc cgaccgacca gagcgtgcgg caatccgaat ggcgtgagcg cgtcgcgacc
     3061 atcgcttctc tccatcctct gtttcatccg cgcgccgtcg cggtcatcgg cgcctcacgc
     3121 gcgccgagga gtatcggata ccggttactc gacgccctcc atcacaatcg gtttgaaggc
     3181 cgctgttatg cgatcaatcc ccatgcgtcc accattgccg gggtcgaggc gtttcccagc
     3241 gtgcgccacc ttccaacacc ggtcgatctc gccgtgatcg ccgttcccaa agaagccgtg
     3301 ctatcggtgg tcgacgaatg cgctgccatc ggggtccgtg cgctggtcgt tatcacggcc
     3361 ggattcgccg aagtcggagc agaaggacgg cggttgcagg accagttgct ggagaaagtc
     3421 cggctacacg ggatgcgtat ggtgggaccc aactgtttcg gcattctgaa cacggatccc
     3481 gccgtgcgat tgaatgccac gttcacgtct acctttccgt gcgcgggctc gatcgccatg
     3541 tcgtcgcaaa gcggcgccct ggggctcgcg ctcgtcgccg cctccgaacg attacacctg
     3601 gggctttcta ccttcgtcag cgtcggcaat aaagctgatg tgtccgtcaa tgatctgctg
     3661 cagtactggg aacaggacac cgcgaccaac gtcatcctgt tgtatgtcga atcgttcggc
     3721 aatcccagac gatttgcaca gatcgcccgg cgagtgagcc gcaacaagcc gatcgtcgtg
     3781 ctcaaagcgg ggcggacctc atcaggaaaa cgagccgcag ggtcccacac tgccgcactg
     3841 gccgccaatg atgtcgcggt ggaagccctc tttcaacaga ccggtatcct gcgcgccgac
     3901 acgttggagg aaatgtttgc cctggcgacc gggctttccg aacaaccgct gccgaaggga
     3961 cggcgtatcg ggatcctgac gaatgccgga ggaccggcca ttctctgcgc ggatgcctgc
     4021 gaggcggccg gcctcgaggt gcctgaattg tcacaagcca ctatttcccg gctgtcgccg
     4081 tttctccccg cctctgcctc actgcgcaat ccggtggact tgatcgcctc cgctaccccc
     4141 gagcaatacg aacaagcgat cgtcgcgcta ttgacctccg aggatatcga tgccctcatc
     4201 attttataca tcgcggtcac ggcgaccgac gtggacccca tcgctcaagg aattgcgcga
     4261 ggaattgaag ccgcacgggc acagcagctg gtcaagaaac cggtctcgat tggatggatg
     4321 gtggaaacgg atcgcgaccg cagattttcg ctcccgcacg aaaccattcc tacgtacagc
     4381 ctgcccgaac tccctgcgcg cgtcctggga aaagttgccg gctacgtcca gtggcgcgat
     4441 cgtcctctcg gcatggtgcc ggacttcgat gatcttgaca tctcgtccat caaaaccgtt
     4501 tgtcgcagcg tgctcgccac gcggggaaac ggctggttaa cggtcacgga aacacgtgcg
     4561 gtcctcagca gcatggggat ttctctgccg ccaggaggcc tggccaccac agctgaagaa
     4621 gcggccacga tcgccgcgca gatcggattt cccgtcgccg tcaaactggc gtcgcatacg
     4681 ttagtccaca agaccgaggt cggcggcgta catctcaatc tttccagcaa ggctgaggtc
     4741 cgccgggcgt acgacgaaat cgccgcacgg ctcgcgcagg accacacgct cgacgccatg
     4801 gaaggggtgt tggttcagtc gatggtcaca aatggcgtcg aggtgatggc ggggatggtg
     4861 caggatcctt cgttcggccc cttgatcggc ttcgggctcg gcgggattca cgtcgaaatt
     4921 ctcggggacg tacgattccg gatcacgccg ttaacagaac tggacgccgc cgacctgata
     4981 cgcagtatca agggctatcg tttgctccag gggtatcggg gccatgcacc gggcgacgtc
     5041 gatgccatcc aggagctcct actgaggctc tcacggttgg ttgaagaggt gccggatatc
     5101 gtggagctcg atctgaaccc gattttcgcc ttgccgccag gccagggcta tcgaatcgtg
     5161 gatgcacgga tcagag
//
LOCUS       DAOQPD010000132         5063 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_10207_length_5063_cov_19.234824, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000132 DAOQPD010000000
VERSION     DAOQPD010000132.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 5063)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5063)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5063
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10207_length_5063_cov_19.234824"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            332..754
                     /locus_tag="PK063_17985"
     CDS             332..754
                     /locus_tag="PK063_17985"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98995.1"
                     /translation="MQFDAALAAQETLQEAQTELGVDWDQATELEETFSSNAGSTARD
                     AYEQLLALAARHPKAHRFQAFCIYITWQQVTEETIARHFQTGMTLAESYLASPDGKDP
                     RHLAHVAELLDSFRAGLGLDEEDDIVVEFRKDTPKGGD"
     gene            840..1607
                     /locus_tag="PK063_17990"
     CDS             840..1607
                     /locus_tag="PK063_17990"
                     /inference="COORDINATES: protein motif:HMM:NF037660.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ98996.1"
                     /translation="MAENDKHRARIFLHRGDLVQARAAWEAAVKDDRLTGTPRELSNS
                     LGNLGNTLALAGAFEEADACYKEVLAIQRNERDPHAIAHTLVNLGNLHIGADKPEKAR
                     PYYLEALDLLKPLNDHRALGILYHNLALEEARQQQWDESVRLFTQALDSHRVVGNEEG
                     LAGTYSQMGKMFLDSGRSVEAERCFNNATEHFIKLGNPSGEAAVLRELADLYEQRQDT
                     IAAIRCVERLHHLALGTGRTPSTADRDRLTRLRAAHS"
     gene            1673..1990
                     /locus_tag="PK063_17995"
     CDS             1673..1990
                     /locus_tag="PK063_17995"
                     /inference="COORDINATES: protein motif:HMM:NF025910.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HMZ98997.1"
                     /translation="MDISAFRQMVEKNPKGFLGRYGLGNKILQEGGSLEEAAEHLTVA
                     TQLDPTHVASHLALGRALVKLGKKEDAKPVLKAGIDAAVSGRSNGGVDLVPELQQLLR
                     TLG"
     gene            2008..2208
                     /locus_tag="PK063_18000"
     CDS             2008..2208
                     /locus_tag="PK063_18000"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98998.1"
                     /translation="MTLDAARQRIESAITQYGQHAAMAIELVINEVRSDMGRDAVNEL
                     IDEFDLELMYNIAPMESDYSNS"
     assembly_gap    2472..2571
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <2572..2951
                     /locus_tag="PK063_18005"
     CDS             <2572..2951
                     /locus_tag="PK063_18005"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ98999.1"
                     /translation="FRFLFDGPVPAGLSRVSSLSAVGLPFKHILASVDLVLTKPGYGT
                     TVESVALGIPVVYVRRYNFADEQSLVDYLQRHGRSAELSLDAFYQGHWEPAIREALAQ
                     SPASPPPPLSGAHDAANILHTYF"
     gene            3075..3680
                     /locus_tag="PK063_18010"
     CDS             3075..3680
                     /locus_tag="PK063_18010"
                     /inference="COORDINATES: protein motif:HMM:NF019265.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HMZ99000.1"
                     /translation="MESAPRQAASTIEPKLLARVAKGDQAAFGQLYDQSSTLLFTLAY
                     RILNDRDEAAELLQDVYLEVWRKIAKYDVGRGSPIAWLVTLTRSRAIDRLRSRASRGQ
                     HVVADSFEHPLVSVTPDVSPNPYEAREDTEMRQMMAKAILDLPLPQQQAIEMAFYQGL
                     THTEIAAKLNQPLGTVKTRIKLAMSKLRASLQETLPQGHQL"
     gene            3677..4693
                     /locus_tag="PK063_18015"
     CDS             3677..4693
                     /locus_tag="PK063_18015"
                     /inference="COORDINATES: protein motif:HMM:NF021604.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma factor"
                     /protein_id="HMZ99001.1"
                     /translation="MTHEELEEAVPLYAIGALERSERQAIEAHLLSGCAACHAALKDY
                     QTVASLLPFGLTPATPPNTLKAKILMAPASTTSQPETEQPGPRSSLEPGEWMNHLFPP
                     ITPARSLPFRIAMGFAALVVVVGGGYLAWMNYTQTAQRSGEIQQLQAAVQRETSRASS
                     LQSELRQREQTLDSLKTDLDQRTTEVAELRDQLLQREAELDDAHQQLTQHDSSLQRLA
                     QQSETFVGLFKNPTSKVVLLSGSDMAKSAGAFLLIDPASKKAWLYAFNLPALPNGKVY
                     QLWAIDDKPVSAGVFGLDAGQKARMLIKNMGEFPRMKKFAVTVEPDGGRPEPSGAIYL
                     IGQI"
     gene            4747..>5063
                     /locus_tag="PK063_18020"
     CDS             4747..>5063
                     /locus_tag="PK063_18020"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0052717 - tRNA-specific adenosine-34
                     deaminase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HMZ99002.1"
                     /translation="MPIVRTRCVLSLTGITHDTMSLPDDLDRQFMQEALSLAREAPLI
                     GEVPIAALLVRDGVVIARAHNLRETVQDPTAHAELLVIREAAKQMNSWRLTESTLYVT
                     LEP"
BASE COUNT         1091 a         1542 c         1375 g          955 t
ORIGIN      
        1 tcgcggacac ggaaatatat ctccggcagg gtaaagacat ttgagcagga ctgaacaagt
       61 tcttgcgccg atgccatgat agacgatcct ccttggtgcg cgttgcgtgc gccctgcaca
      121 ggggcccccg gctatcttta tcggtcgcgg cccgtctttt ctgaagcgcg agggctattc
      181 ggcctataca tgaggcctgt ttccctcccg atcgacctga tgaacccgtt ccaccgggcc
      241 acttctggat cagcaacatt gacctccctt ccgcgcaccc agtattctgc aatcaatccg
      301 gaagccccac atcaatcccg ttgaggactg catgcaattc gacgccgcgt tggccgcaca
      361 agaaacgtta caggaagcgc aaaccgagct tggtgtcgac tgggaccagg ccactgaatt
      421 ggaggagacg ttttcctcca atgccggctc gaccgccaga gacgcctacg aacagcttct
      481 cgcgctggcc gcccgacatc ccaaggccca tcggtttcag gccttctgca tttacatcac
      541 ctggcagcag gtcaccgaag agacgatcgc ccgtcacttt cagaccggca tgactctggc
      601 cgaatcctac ctggcctcgc ctgatgggaa ggatccacgg cacctcgcgc atgtcgccga
      661 attgctcgac tcgtttcgcg caggcttggg actggatgag gaagacgaca tcgtagtgga
      721 gtttcgaaaa gacacaccca aaggcggaga ctaacgtggg ccgcgagacg tcacccgtga
      781 acgggaaacc gttccggacg cgagagacga gcaacgagag gcaacatcgg ttctgacgta
      841 tggctgaaaa cgataaacat cgcgcgcgca tttttcttca tcgaggggat ctcgtccaag
      901 cccgggccgc ctgggaggcc gcggtgaagg atgatcgcct tacgggaacg ccacgggaac
      961 tctccaatag tctcggcaat ctaggcaaca ccctggcact cgccggcgcc ttcgaggaag
     1021 ctgatgcctg ttacaaagaa gtgctcgcca tccaacgcaa cgagcgcgac ccgcatgcca
     1081 ttgcccacac tctcgtaaat ctgggcaatc tccacatcgg cgcggataaa ccggagaaag
     1141 cccgtcccta ctatctcgaa gcgctggacc tgttgaaacc actcaatgac catcgagcgc
     1201 tgggcattct ctaccacaat ctcgcgctgg aagaagcccg gcaacagcag tgggatgaat
     1261 ccgtgcggct gttcacccag gccctggatt cccatcgcgt ggtgggcaat gaagaaggcc
     1321 tggcgggaac ctacagtcag atgggaaaaa tgtttctgga cagtggacgc tctgtggagg
     1381 cggaacgctg tttcaacaat gccaccgaac atttcatcaa gctcggcaac ccgtccggcg
     1441 aggccgcggt gttgcgggaa ctcgccgacc tctatgagca acggcaggac accattgctg
     1501 ctatccgttg cgtggagcgg ctccatcacc tggccttggg caccgggcgt accccttcga
     1561 cggcagaccg ggatcgcctc acacggcttc gcgccgccca tagctgaacg gatgggggtg
     1621 atgctaaaat tcgcccgtct cgattgaaca acgatgcttc acaaggagtg ccatggatat
     1681 cagcgcgttt cgtcaaatgg tggagaaaaa tcccaaagga tttctgggcc ggtacggtct
     1741 gggcaataaa attttgcagg aaggcggcag ccttgaggaa gcggcagagc acctgacggt
     1801 ggcgacgcaa ttggatccga cgcacgtcgc ttcacacctt gccctcggac gcgcgctcgt
     1861 gaaactgggg aagaaagagg atgccaagcc cgtcttgaaa gccggtattg acgcggccgt
     1921 gtccggccga tccaacgggg gcgtggactt ggtgccggaa ctgcaacagt tgttacgaac
     1981 actcggctaa ggccggctgg aggacttatg actctcgacg cagccagaca gcggattgaa
     2041 tccgcgatca ctcaatatgg gcagcatgca gccatggcca ttgaactggt catcaacgag
     2101 gtccgctctg acatgggccg tgacgccgtg aacgaactga tcgatgagtt cgatttggaa
     2161 ctcatgtaca acatcgctcc gatggaatcc gattactcga acagctaaag caagatggag
     2221 ctgaactgca cagcccttct agggtgctca aaaaggccat ccaacgaggc cgcagacgag
     2281 gaagacccgg agacgtacgt tcagaggtac gttgaggagg attccgagtc gagaacgacg
     2341 ttgggggcct ttttcagcag cctgcgatgc cgttgatctg gtgctccatt tccggccacg
     2401 gctacggcca cgccgcgcaa gtcgtaccgg tgctcaacgc gctcgctcgt ctcgtacccg
     2461 atctcaaggc gnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ngctttcggt
     2581 ttctctttga tggtcctgtg ccggcgggac tttcccgggt ctcgtcgctc tctgctgtcg
     2641 gactgccgtt caagcacatc ctggcatctg tcgatctggt gctgaccaag cccgggtatg
     2701 ggaccaccgt tgaatcggtc gcgctcggga ttcccgtggt ctacgtacgt cgctacaatt
     2761 tcgcagacga acaatctctc gtggattacc tgcagcgaca cggccgatcc gcggaactct
     2821 ctctcgatgc tttttatcag ggacattggg agccggccat ccgggaggcc ctggcccaat
     2881 cacctgcatc gccgcctccc cccttgtcag gggctcacga tgccgccaac atcctgcata
     2941 cgtatttcta aacagacgcc ccattccagc cgcgcacgac gcacaaactt acatctgatt
     3001 agtcgttttt ctcagacagt gttatagtgg gcccaattct gatcccgagg actgtgcgcg
     3061 cctaggccga ctgcatggaa tccgctcccc gacaagccgc atccacaatt gaacccaaac
     3121 tcctggcccg cgtggcgaag ggggatcaag cggcattcgg ccagctttac gatcaatcct
     3181 ccaccctgct ctttaccctg gcgtaccgga tcctcaacga tcgcgatgaa gcggcggaac
     3241 tcctccagga tgtgtacctg gaagtctggc gaaaaatcgc caaatacgat gtcggtcgag
     3301 gaagccccat cgcctggctg gtgaccctga cccgtagccg tgccatcgat cggctgcgct
     3361 cgcgtgcctc gcgcgggcag cacgtcgtcg ccgattcgtt cgagcacccg ctggtctccg
     3421 tcacgcccga cgtgagcccc aatccatatg aagccaggga agacactgag atgcgccaaa
     3481 tgatggcgaa ggctattctc gatctgccgc ttcctcagca acaagcgatc gaaatggctt
     3541 tttatcaggg actgacgcat acggagatcg cggcgaaatt gaatcagccg ttgggcaccg
     3601 tcaagacgag aatcaaactg gccatgtcga aacttcgcgc ctccttgcag gagacgctgc
     3661 cgcaagggca ccaattatga cccacgagga actggaagaa gcggttcccc tctatgcgat
     3721 cggcgccctc gaacgctctg agcggcaggc catcgaggca catctactct ccggctgcgc
     3781 cgcctgtcat gccgccttga aggattatca aaccgtcgct tcgctgctgc cgttcggact
     3841 gacgcccgca acgcccccga acacgctcaa agccaagatc ctgatggccc cggcatcgac
     3901 cacaagccag cctgaaacgg agcagccggg acctcgatcc agcctcgaac cgggcgaatg
     3961 gatgaatcat ctgtttcctc ccatcacgcc tgcccgttcc ctgccgttcc gcatcgccat
     4021 gggatttgca gccctcgtgg tggttgttgg aggcggatat ctcgcctgga tgaactacac
     4081 gcagacagcc cagcgctcag gcgaaatcca gcagttgcaa gccgcggtgc agcgcgaaac
     4141 ctcccgcgcg tccagtctgc agtcggaatt gcgccagcgc gaacagacct tggattcgct
     4201 gaagactgat ttggatcaac gcacgactga agtggccgag ttgcgggatc aattacttca
     4261 acgggaggcc gagctggatg atgcgcatca acaactcact cagcatgaca gttcattaca
     4321 gcggcttgcc cagcaaagcg aaacatttgt cgggctgttt aaaaatccaa catcgaaagt
     4381 cgtcttacta tccggctccg acatggcgaa atcagccggc gcatttctcc tgatcgatcc
     4441 cgcgagcaag aaggcatggc tctacgcctt caacttacca gcgctcccga acggcaaggt
     4501 gtatcaactc tgggccatcg atgacaaacc ggtcagtgcc ggggtgtttg gcctggatgc
     4561 aggccagaaa gcccgcatgc tgattaagaa tatgggtgag tttccccgga tgaagaaatt
     4621 cgccgtgacc gtggaaccgg acggcggacg ccccgaaccg tcgggggcca tctacctgat
     4681 cggtcaaatc tagcctcagt ccctccaacg aacgtcgcct gcgattcccg gcccaaacat
     4741 gctagcatgc ccatcgtcag aacccgatgc gtgctctcgt tgacgggaat cactcacgac
     4801 accatgtccc tgcccgacga cctcgataga caattcatgc aagaggccct cagccttgcg
     4861 cgggaagccc cgctgatcgg cgaagtcccc atcgccgccc tcctcgtccg cgatggcgtc
     4921 gtcatcgccc gggcgcacaa tctgcgggaa accgttcagg accccacagc acatgcagag
     4981 ctgcttgtca tccgtgaagc agccaaacag atgaacagct ggcgcctcac cgagagcacc
     5041 ctctatgtca ccctggaacc ctg
//
LOCUS       DAOQPD010000133         4971 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_10504_length_4971_cov_15.105574, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000133 DAOQPD010000000
VERSION     DAOQPD010000133.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 4971)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4971)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4971
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10504_length_4971_cov_15.105574"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(90..791)
                     /locus_tag="PK063_18025"
     CDS             complement(90..791)
                     /locus_tag="PK063_18025"
                     /inference="COORDINATES: protein motif:HMM:NF012257.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HMZ99003.1"
                     /translation="MRDCEPVRVQCHLARMPLFAGLSVDLIERIAHKIVPITVLKGHA
                     LFHAGDNCKGMYLVVFGQFKLVFTSFVGAEKVVEIIQQGESFGEAIMLAEKNHLTSAY
                     ALQDSLVLHVPTAAILAELNNDPKLTARMIILLAKQNVRFMNDIESYALQSATQRIIG
                     YFTNEIPDEAIKADELELELHVHKGVIASMLNITQEHFSRILSDLSARGLILISGRSI
                     RIPKISNLIAFQRSP"
     gene            1280..1885
                     /locus_tag="PK063_18030"
     CDS             1280..1885
                     /locus_tag="PK063_18030"
                     /inference="COORDINATES: protein motif:HMM:NF019958.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HMZ99004.1"
                     /translation="MSLNARQSTESRQSEIIATVVALAAERNPAEVTTTDIAKAMSVT
                     QGALFRHFPTKEAIRLAVIEWVETQLMANLADAQASAPDVLSGLEAMFLAHVKFIRQF
                     PGVPRLVFAELQQPDSSPLRQRVQQIMQRYRQMLAEALGKAKAAHLIRDDVDVQAAAV
                     LFLGAIQGLVMQSMLGGVSPDAEEPVLGVLRLYLASLGGKS"
     gene            1882..3072
                     /locus_tag="PK063_18035"
     CDS             1882..3072
                     /locus_tag="PK063_18035"
                     /inference="COORDINATES: protein motif:HMM:TIGR01730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HMZ99005.1"
                     /translation="MKPSQFISRKFGLWLFAVVLLLGFGVVVARSGPLSPIQVTTLRV
                     EAGSLSPAIFGIGTVEARRSYLIGPTAAGRVKAVHVDVGETVKAGQLLAEIDPVDLDE
                     RLRSTEAAYARAASAVTAAEAQRKDALARRQLAELNAKRYRDLGGKNFVSTSAVEGKQ
                     QELDSAQAAVEASEANLQGARQDQLRLKADQEGIRQQRGNLRLLAPRDGLVTSRDAEP
                     GSTVIAGQAALRLVEPDSLWVKARLDQGRSRGLAVGQMADIVLRSNASTHYPGKVARI
                     EPVSDSVTEERIAQIAFERIPEGLSVGEMTEVTVKTGATQSGLLLPNAAIKQMPQGRG
                     VWKLKDGKPRLILVKLGDTGLDGTVQILEGLAAGDEVVIHSERELNEGTRIKVVSQIV
                     GKPK"
     gene            3069..4262
                     /locus_tag="PK063_18040"
     CDS             3069..4262
                     /locus_tag="PK063_18040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011734096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HMZ99006.1"
                     /translation="MISLAGRDILHSWSKFVLTGIGLGLLIGVTLSMAGIYRGMVDDA
                     KALLNNSGADIWVVQQETQGPYAESSSLRDDVYRALLALPGVSRAANVTYLTMQVRLD
                     NTDVRAMVVGFEPGQPGEPSYLIAGRHITRSHYEAVADVKTGFQLGDTIRIRRHDYRV
                     VGLTRRMVSSGGDPMVFIPLKDAQEAQFLKDNDAILNERARTTANPSLNRPGVPGLLD
                     AILAAQNANHNVNAVLVQIAPGIESEQVASEIRRWKHLQAFTRAQMEEILVSKLIATS
                     AKQIGMFLVILAIVSAAIVAFIIYTMTLGKIREIAVLKLIGTRNRTIAGMILQQAMGL
                     GLIGFMVGKTAATLWAPFFPKFVLLEPGDAVRGFIVVMLICALASTLAIRVALRVDPA
                     TAIGG"
     gene            4264..4968
                     /locus_tag="PK063_18045"
     CDS             4264..4968
                     /locus_tag="PK063_18045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005997848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HMZ99007.1"
                     /translation="MKGFGIHIEGLRKRYGEGDTAVDALKNVNMTVAPGEVVGLIGPS
                     GSGKSTLLKCLGAVIEPTAGRMTLGDEVIFEDGWKIPDLRALRRDRIGFVFQAPYLIP
                     FLDVTDNVALLPMLAGKPNGEARKRANELLDALDVGHRAKANPSQLSGGEQQRVAIAR
                     ALANQPPVILADEPTAPLDSERALSVVRILNDMAQQFRTAIIVVTHDEKIIPTFKRIY
                     HIRDGKTFEEQGLGAA"
BASE COUNT         1113 a         1368 c         1388 g         1102 t
ORIGIN      
        1 ggccccgact ctctgcaaac gttggtctag tagccgtccc ggcaataact gcctcatact
       61 ggaaggcata tttgagagcc gtgtcgggcc tagggtgatc gttgaaacgc tataagattt
      121 gagatctttg ggatgcggat agatctacca ctaatcagga ttaagccgcg cgcggaaagg
      181 tcactcagaa tcctggagaa atgctcttgg gtgatgttca gcattgaggc gatgacacct
      241 ttatgtacgt gcaattccaa ctctagctcg tctgccttaa tcgcctcatc aggtatctcg
      301 ttcgtaaaat acccgatgat ccgctgggtg gcggattgca acgcgtagga ctcaatgtca
      361 ttcatgaacc ggacattttg cttcgcaaga agaataatca tccttgccgt tagtttcgga
      421 tcgttgttca gttccgccaa aatcgccgcc gtcggtacat gtagcacaag tgaatcctga
      481 agtgcatagg cagaagtaag gtgatttttc tctgcaagca tgattgcctc accgaagctc
      541 tcaccttgtt gaataatttc aacgactttc tcagcgccta cgaaggaagt aaaaacgagt
      601 ttaaattgcc cgaacacaac gagatacatg cccttgcaat tgtctccagc atgaaaaagt
      661 gcatgaccct tcaatacggt gatcggcacg atcttgtgtg caattcgctc aatgaggtca
      721 acgcttaagc ctgcaaataa tggcattcga gcaagatgac attgaaccct tacaggctcg
      781 caatcacgca tcactttccc ctttaagtat ggctatgtat ttatcttaaa ttgattcaac
      841 tcaaattacc gaggaatatc tctacccatg tctcgacacg ccaatatgcg cggatagtcc
      901 atcactgggc cgaggctgcc ggtcttgatt catctgccta cgggaccgca ttccatgctg
      961 aggacgaagg caggtacctg cctaagccga cgttgattaa ctcaccgaag cgctcgattt
     1021 aatcaagcag atttgatagg tgtagggcgc ttaaacttaa acgaatgacc ctacatgtcg
     1081 ctctctcgct cttccgaaag gagaacgaac tttccaaggt tgatctccct cggtcctctc
     1141 aacggctcac ttcggctata gctgctatga cggagaaagc agcttccgta acaaacagtt
     1201 tcaattggcg gatggaatat tagacaagtc taaaatttat tggctatact tgtaagtaac
     1261 ttattacata caagtagcta tgtctcttaa tgctcgccag tcaactgagt cccgacagtc
     1321 agaaatcatc gccaccgtgg tggccttggc tgccgagcga aatcctgccg aggtcacgac
     1381 gaccgacatt gccaaggcga tgagtgtgac gcagggggca ctgttccgtc actttccgac
     1441 caaagaggca attcgcctgg ctgtcatcga atgggttgaa acgcaactga tggccaacct
     1501 cgcggatgca caagcatctg cccctgatgt cctgagcggc ctggaagcga tgttcctggc
     1561 tcatgtgaaa ttcattcgcc aatttccagg tgttccgcgc ctggtctttg ccgaactcca
     1621 gcagccggat agctcgcccc tacggcagcg cgtgcaacaa atcatgcagc gctatcggca
     1681 gatgttggct gaagccttgg gcaaagcaaa agcggcccat ttgataagag acgatgtgga
     1741 tgtccaggct gccgctgtgc tatttctcgg tgccatccag gggctggtga tgcagtccat
     1801 gcttggtggc gtctcaccag atgccgaaga gccggtactg ggcgtcttac gcctctacct
     1861 tgccagcctg ggaggcaaat catgaaaccc agccaattca ttagccgtaa gtttggactt
     1921 tggctgtttg cagtcgtgct cctcttagga tttggtgtgg ttgtcgctcg ttcagggccg
     1981 ctatctccta tccaggtcac aacactccga gtagaagctg gttcgctgtc ccctgcgata
     2041 tttggtatcg gcacggtcga agctcgccgt agctatctca tcggcccaac ggctgcggga
     2101 cgcgttaaag ccgtgcatgt ggatgtgggc gagacggtca aggctggaca attacttgcg
     2161 gaaattgacc ccgttgacct ggatgagcgc cttcgttcga cggaagccgc ttatgcccgg
     2221 gcggccagtg cagtcaccgc tgccgaagcg caacgcaagg atgccttggc cagacgccaa
     2281 ctcgcggaac tcaatgccaa acgctaccgt gatttgggcg gaaagaattt cgtcagcacc
     2341 agcgcggtgg aaggcaagca acaggaactg gattcggctc aggccgcagt tgaggccagc
     2401 gaggctaacc tgcaaggcgc ccgccaggac caacttcgcc tgaaggctga ccaggaaggc
     2461 atccgccaac aacgcggcaa cctgcgtctg ctggccccgc gggatggctt ggtgacgagc
     2521 cgcgatgcgg aaccgggctc gacggtgatt gccggccagg cggcgctccg tttggttgag
     2581 cctgacagtc tctgggtcaa ggcacgcttg gaccagggcc gctcgcgtgg cctggccgta
     2641 ggccaaatgg cggatattgt gttgcgcagc aatgcctcga cccactatcc cggcaaggtg
     2701 gcacgtatag agccggtgag tgacagcgtc acggaggagc gcatcgctca aatcgcgttc
     2761 gaacgcatcc ccgagggact gagcgttggc gagatgaccg aagttaccgt gaagactggg
     2821 gcaactcaat ccggactgct gctccctaac gccgccatca aacagatgcc ccaaggccgc
     2881 ggcgtctgga agctgaagga tggcaagccc agactgattc tggtgaagct gggggacaca
     2941 ggtcttgatg gaaccgtgca gattctcgaa ggtctggctg cgggtgacga ggtggtcatc
     3001 cacagcgagc gcgaactcaa cgaaggcacc cgcattaagg tcgtcagcca aatcgtgggg
     3061 aaacccaagt gattagcctg gccgggcggg atatcctgca ttcatggtca aagttcgtcc
     3121 tgaccggtat cggcctgggt ttgttgattg gcgtgacatt gagcatggcc ggtatttatc
     3181 gtggcatggt cgacgacgcc aaggcgctgc tcaacaacag tggggccgac atatgggtag
     3241 tgcaacaaga gacccaaggc ccttacgccg aatcatcgag cctgcgtgat gatgtctatc
     3301 gggccttact cgctctgccg ggggtttccc gcgcggccaa tgtcacctat ttgacgatgc
     3361 aggttcgcct cgacaatacg gatgttcggg ccatggtggt tggcttcgaa cctgggcaac
     3421 ccggcgagcc cagctacctg attgccggcc ggcacatcac ccgcagccat tacgaggcag
     3481 tcgccgatgt gaagaccggt tttcaattgg gcgacacaat acgtattcgc cgccacgact
     3541 atcgcgtggt tggccttaca cggcgcatgg tctcgtcggg cggcgacccg atggttttca
     3601 tcccgctcaa ggatgcgcag gaagcacagt ttctcaagga caacgacgcc attctcaatg
     3661 aacgcgcccg cacaactgcc aatccaagcc tgaaccgacc cggcgtacca ggcctgctcg
     3721 acgccatcct ggctgcgcag aacgccaatc acaacgtcaa tgcggtactg gttcagattg
     3781 ccccaggcat cgagtctgaa caggtggcaa gtgaaattcg ccgctggaag catctgcaag
     3841 cttttacccg tgcccagatg gaggagattc tggtctccaa gctgattgcc acctccgcca
     3901 aacaaatcgg catgttcctg gtcattctgg ccatcgtcag cgccgccatc gtcgctttca
     3961 tcatctacac catgacgctg ggcaaaataa gggagatagc tgttctgaag ctcatcggca
     4021 cccgcaatcg gacaattgca gggatgattc ttcaacaggc catgggactt ggcctcattg
     4081 gtttcatggt cggcaagact gccgcgaccc tatgggcgcc attcttcccg aaatttgtcc
     4141 tcctcgaacc gggcgatgcg gtacggggat tcatcgtagt gatgctcatc tgcgctctgg
     4201 ccagcacgct cgccattcgt gttgccttgc gtgtcgaccc ggctacggct atcggaggtt
     4261 aaggtgaaag gttttgggat tcacatcgag ggtctgcgca aacgctatgg cgaaggcgat
     4321 acggcggtcg acgcccttaa aaatgtcaat atgaccgtgg cgcccggtga ggtggtcggt
     4381 ctgataggtc cctctggctc gggaaaaagc accttgctga aatgcctggg cgctgtcatc
     4441 gagcctacgg ctggccggat gactctgggt gatgaggtga ttttcgagga tggctggaag
     4501 attccggacc tcagagccct gcgtcgcgac cggattggct ttgtatttca ggcgccttac
     4561 ctgattcctt ttctggacgt caccgataac gtggccttgt tgccgatgct ggccggcaag
     4621 ccaaatggcg aagcgcgaaa gcgggctaat gaattactgg atgcgctcga tgtcggtcac
     4681 cgcgccaagg cgaatccctc acagctctcc ggtggcgagc agcaacgcgt ggcaattgcg
     4741 cgcgctttgg cgaatcaacc gccggtgatt ctggcagacg aaccgacggc cccgctggat
     4801 agcgaacggg cgctcagcgt cgtacgtatt ctcaacgata tggcccagca gtttcgaacc
     4861 gccattattg tggttaccca cgacgagaaa atcattccca ccttcaagcg catctatcac
     4921 attcgggacg gcaaaacctt tgaagagcaa ggactcgggg cagcctagtt t
//
LOCUS       DAOQPD010000134         4878 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_10802_length_4878_cov_21.207962, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000134 DAOQPD010000000
VERSION     DAOQPD010000134.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 4878)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4878)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4878
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10802_length_4878_cov_21.207962"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1063)
                     /locus_tag="PK063_18050"
     CDS             complement(<1..1063)
                     /locus_tag="PK063_18050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HMZ99008.1"
                     /translation="MPDTAVLNVDLADVWKERGRKNCIRTIAWGDEITVVQQTATYLE
                     VTITFFREKPDGSILPESITGYIEPTKSSGIKVSDVVRPVADNKVLKVNFVDVQQGDG
                     MVIESPDGKVLLIDGGDNQMFARYLAGRFRNTSLQQPKAIDCIIVTHGDADHFAGLSE
                     ILKSETNKVKRKQLFIQPQRIYHNGLVKRPTRMNNKAVPDTKLLGPTKTVGGTLYLTG
                     LEENLLDVDDKDMNEPFREWKQTLAAYNSRSPVSFRRLQLGDTQAFEFFNRNDLRIDV
                     LGPITTDVAGQPALRFLGEPPTGPRIGHDSLNDSDEGFTGHSASHTINGHSIVLRLSY
                     GGFSFLFSGDLNDEASRFLA"
     gene            1231..1872
                     /locus_tag="PK063_18055"
     CDS             1231..1872
                     /locus_tag="PK063_18055"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0016018 - cyclosporin A binding [Evidence
                     IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HMZ99009.1"
                     /translation="MPSTREWRPDDCGDRIRRSSREITQSALLPMESPACYICPMTMQ
                     FQKKDPRATIITPFGEIRIRFYPDDAPRHVENFINLAKMGFYDDTTFHRVVPGFIIQG
                     GDPLSKTPDRLLHGTGGPGYFLNPETNDRPHKRGAISMAKMPRDGNSTRDFNDNGSQF
                     FISLQDNGGLDRRYSIFGEIIRGIEVIDMIAKMPCDERDNPLEPIRMKVTVKE"
     gene            1934..2344
                     /locus_tag="PK063_18060"
     CDS             1934..2344
                     /locus_tag="PK063_18060"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99010.1"
                     /translation="MTTLLPLPGRSLLQNLGPCLLLLPILLTACDGHRQRLMTEHYPS
                     YPDSVRWAIDKGNILRGMTEDQVYLALGSPVCKKDVVDEGRTVTVWLYPPIGRNACVT
                     SAFRVYFEQGAVTTWDRYSTPTRYTDPVGGVPLY"
     gene            complement(2885..4117)
                     /gene="amrB"
                     /locus_tag="PK063_18065"
     CDS             complement(2885..4117)
                     /gene="amrB"
                     /locus_tag="PK063_18065"
                     /inference="COORDINATES: protein motif:HMM:TIGR04336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AmmeMemoRadiSam system protein B"
                     /protein_id="HMZ99011.1"
                     /translation="MTAKDPKQYPLLRNLQFSPIKEGEEQFIVLWDPTGLSKERLVLP
                     LNYFFIVQHLDGEHSVQDIGAIYLKRFGEFLMPNKVEQLLADLDTKLFLEGERTEQAK
                     QQALAAYRVAPSRSAQFAGRSYEADPAKLRAQINNFFVSKEGPEVKASEHKGKLIKAL
                     VAPTYEMKQAGPIYAWAYKELQDAQKPDFYVLIGTAHSGLEHPVAVTDKDFQTPLGLV
                     KVERAVTDRLREQIPAAFTDELAHHNEHALEFQLPFLQETLGQDQAFTIVPILTAFSA
                     DSLRDPQIREQVETFLQTLKDALAATGKSYCVVVGAELAHIGMRYGDSAPPTDFSFHR
                     CMQTDLEMLKHVENRDPEEFAKFIQKENDQRRISGFSPIYSMLRLIQAETGQVLRYDR
                     GITDQYNSTVTYASMAFF"
     gene            complement(4337..>4878)
                     /locus_tag="PK063_18070"
     CDS             complement(4337..>4878)
                     /locus_tag="PK063_18070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99012.1"
                     /translation="LIPVGIGMLMLTRYVPKAAWLSRYAFAFIVGVGAGLAIPRTISS
                     FILKQIEDTVRPLLGIAPGGGVTFDYSLLNPASHLNGIIILIGVVSVLFYFFFSVEHS
                     GPGKAVARAGILFLMISFGAAFGYTVMARMSLLIGRLTDLIEFSDASYGRPTLWLVLL
                     TVATLIVLSRRGSTHPPNQ"
BASE COUNT          982 a         1359 c         1495 g         1042 t
ORIGIN      
        1 gggcgaggaa gcgactggcc tcgtcgttca ggtcccccga aaacagaaag ctgaatccgc
       61 cgtagctgag gcgcagcacg atcgaatggc cgttgatggt gtgggaggcg gaatggccgg
      121 tgaacccttc atcgctgtca ttgagcgagt catgcccgat gcgtggccct gtgggcggtt
      181 caccgagaaa acgcagcgcc ggctgccctg ccacatccgt cgtgatggga cccaacacgt
      241 cgatgcgcag gtcgttgcgg ttgaaaaatt cgaaggcctg ggtatctcca agttgcaagc
      301 ggcggaagct gaccgggctg cggctgttgt aggcggccag agtctgtttc cattctctga
      361 acggctcatt catgtccttg tcgtcgacgt ccagcagatt ctcttccagc ccggtgaggt
      421 agagcgtccc cccgaccgtc ttggtcggtc caaggagctt ggtgtcgggc accgctttgt
      481 tgttcatcct ggtcggacgt ttgacgaggc cgttgtggta gatgcgctgt ggctggatga
      541 agagttgttt gcgtttgacc ttgttggttt cggatttgag gatctcactg agtccggcga
      601 agtggtccgc gtcgccatgg gtgacgatga tgcagtcgat ggccttcggc tgctggagac
      661 tggtgttgcg gaaacggccg gcgaggtagc gggcgaacat ctgattgtct cctccgtcga
      721 tgaggaggac cttgccgtcc ggcgattcga tgaccatacc gtcgccctgt tgcacatcga
      781 cgaagttgac cttcaagact ttgttgtccg ccacgggtcg gaccacatcg gacaccttga
      841 tgccggaaga tttggtcggt tcgatgtaac cggtgatgga ttcgggaaga atgctgccgt
      901 cgggtttttc gcgaaagaag gtgatcgtga cttcgaggta ggtggcggtc tgctggacca
      961 cggtgatttc atcgccccag gcgatcgtgc gaatgcaatt tttgcggccc cgctccttcc
     1021 acacgtcagc cagatcgaca ttgagcacgg ctgtgtcagg catctgctct ctccccctgc
     1081 aggctggtca gaatgacgcc cggcggtgtt ctcggtcgtt cgtctccctg cgacgtaccg
     1141 caagggtacg cctcagtcgc cgaccttcct gcggccttgc cggaacgcca ttctgatcag
     1201 tctgcacata gttgtggccg cctcggtctc atgccatcga ctcgtgaatg gcggccggat
     1261 gattgcggcg acagaatacg ccgttcatcg agagaaatca cgcaatccgc cctcttgccg
     1321 atggaatcgc cggcctgtta catttgcccc atgaccatgc aatttcagaa aaaagatcca
     1381 cgtgccacga tcatcacgcc cttcggtgaa atccggatcc gtttttaccc ggacgatgcc
     1441 ccgcgtcatg tcgaaaactt catcaacctg gcgaagatgg gcttttatga cgacaccacg
     1501 ttccatcgtg tggtgccggg cttcatcatt caaggcggtg atccgttgag caagacgccg
     1561 gaccgcctgc tgcacggcac cggaggtccc ggatactttc tcaatcctga aaccaacgac
     1621 cggcctcata aacgcggtgc gatttcgatg gcgaagatgc ctcgcgacgg caacagcacg
     1681 cgcgacttca acgacaacgg ctctcagttt ttcatttcgc tgcaggacaa tggcggtctc
     1741 gatcgtcgct actcgatttt cggcgaaatc atccggggca tcgaggtcat cgatatgatc
     1801 gcgaaaatgc cctgtgacga acgcgacaac ccgctggaac cgatccgcat gaaggtgacg
     1861 gtgaaagaat aacctcgctg tgctatgagg cctggccgtt tcccgacgac tctgtcagct
     1921 ctgttgattt attgtgacaa cactcctccc cttgccaggt cggtcgcttc tacagaacct
     1981 ggggccttgc ctgctgctcc ttcccatctt gctgacggcc tgcgatggcc atcgacagcg
     2041 cttgatgacg gagcactatc cttcgtatcc ggacagcgtg cgctgggcga ttgataaggg
     2101 caacattctt cgcggcatga cggaagatca ggtgtacctg gcgcttggct cgccggtgtg
     2161 caagaaggac gtggtggatg aggggcgcac agtcacggtc tggctctatc cgccgatcgg
     2221 acgcaacgcc tgcgtcacca gtgcctttcg tgtctacttc gaacagggcg ccgtcaccac
     2281 ctgggaccgc tatagcacgc cgaccaggta tactgatcct gtcggcggcg tccctctcta
     2341 ctagcaggag ggtgaaaaag cccctcagct ttgttctggc atcgcttcga tcctcaacgt
     2401 accgcaaggg tacgcctcgt cccttcgctc gctgcggccg cgctgggcgg actttttccc
     2461 ctcctgtgcc ataccctgcg gagcatgaac gcacacacgt gtactgagag tcgcacgata
     2521 attctgaatt gtgctgaggt gttgaaattg ggtgctggtt gctcaatcgg ttatccggcg
     2581 aagccgcagg cgtagtgtga ggccgagaag gaaggacagc agtttatttc gcaggtttcc
     2641 cgaggaacgg tcaaaacgac tgtccatcga ggccgcagct agcgaaggag tgagttacgt
     2701 agccttgcgc tacgttgagc gagctgagcg acgcgagaac gatggggcgc ttcacatgca
     2761 ggctgctcaa aaagcccgtc cagcaaggcc gcaggcgaga gaaaaccgga ggcgtagcct
     2821 ctggctacgt tgaggatttt gtcgagctga gaacgcaggt ggcggggttt ttcagcagcc
     2881 tgccctagaa gaaggccatg ctggcatacg tcacggtcga attatactga tccgtgatcc
     2941 cgcgatcgta ccgcagcacc tgccctgttt ccgcctgaat cagacgcagc atcgagtaga
     3001 tcggcgagaa gccggagatg cggcgctggt cgttttcttt ctgaatgaac ttggcgaatt
     3061 cttccgggtc gcgattctcg acatgcttga gcatctcgag gtcggtctgc atgcagcgat
     3121 ggaaggagaa gtcggtcggc ggggccgagt cgccgtagcg catgccgata tgggcgagtt
     3181 ccgccccgac cacgacgcaa taagatttgc cggtggcggc gagcgcgtct tttaaggtct
     3241 gaagaaacgt ctcgacctgc tcccggatct gcggatcgcg cagactgtcc gccgaaaacg
     3301 ccgtgaggat cggaacaatc gtaaaggcct ggtcttggcc gagagtctct tgcaggaacg
     3361 gcaactgaaa ttccaatgca tgttcattat gatgtgccaa ttcgtcggtg aaagcggcgg
     3421 ggatctgttc gcgcaggcgg tcggtgaccg cgcgttcgac cttcacgagc cccaatggtg
     3481 tctggaaatc cttgtcggtg acggctactg gatgctcgag cccggagtga gcggtgccga
     3541 tcagcacata gaaatcaggc ttctgggcgt cctgcaattc cttatacgcc caggcataga
     3601 tcggtccggc ttgtttcatc tcgtaggtgg gcgcgacgag agccttgatg agtttgccct
     3661 tgtgttcgga ggccttcacc tccggtccct ctttcgatac gaaaaaattg ttgatctggg
     3721 cgcgcaactt cgcgggatcg gcttcatagc tgcggccggc gaactgcgct gagcgggaag
     3781 gggccacgcg ataggcagcc agcgcctgct gcttggcttg ctcggtgcgc tccccttcga
     3841 gaaagagttt ggtgtccaga tcggccaata actgctcgac cttattcggc atcaggaatt
     3901 cgccgaagcg cttcagataa atggccccga tgtcctgcac gctgtgctct ccgtcgaggt
     3961 gctgtacgat gaagaaataa ttcaacggca ggacgaggcg ttccttgctc aatccggtgg
     4021 ggtcccagag cacgatgaac tgctcctccc cttccttgat cggcgaaaat tgcagattgc
     4081 gcagcagcgg atactgcttg ggatctttgg cagtcatggt cggtgtggat tccatagtgg
     4141 cggcattgta acggagcaaa cttctcaggc gcaacagcct tgaggaacgt cgttcgtgaa
     4201 gcgtgaagcc aatctccagg agaccgtatt tcgtatctcg tgaagcgtct cgtggggacg
     4261 aaatgacgcg cagggtcgtc gccgagctgc tcttgcgaac gacgagagac gagggacgaa
     4321 caacggcacc gggcgcctac tgattcggcg gatgggtgct gccgcggcgg ctgaggacaa
     4381 tcagagtggc gacggtcagg agcaccagcc agagcgtggg gcgtccgtag gaggcgtctg
     4441 agaattcaat cagatcggtc aggcgaccaa tcaacagcga catgcgggcc atcacggtgt
     4501 agccgaaggc ggcgccgaag gaaatcatca gaaagagaat ccctgcgcgt gcgacggcct
     4561 tgcctggacc ggaatgttcc accgagaaga agaagtaaaa cagcacggac acgacgccga
     4621 tcaggatgat gatgccgttc agatggctcg ccggattgag cagcgaatag tcgaaggtca
     4681 cgcctccgcc gggggcgatg cccaggagcg gccgtacggt atcctcgatc tgtttcaaaa
     4741 tgaacgacga gatcgttcgc ggaatcgcca atcccgcccc gacgccgacg atgaacgcga
     4801 aggcatagcg cgacagccag gctgccttcg ggacataacg cgtgagcatg agcattccga
     4861 tgccgaccgg aatcagca
//
LOCUS       DAOQPD010000135         4851 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_10887_length_4851_cov_21.160133, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000135 DAOQPD010000000
VERSION     DAOQPD010000135.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 4851)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4851)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4851
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10887_length_4851_cov_21.160133"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..461
                     /locus_tag="PK063_18075"
     CDS             <1..461
                     /locus_tag="PK063_18075"
                     /inference="COORDINATES: protein motif:HMM:NF017868.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="gamma-glutamylcyclotransferase"
                     /protein_id="HMZ99013.1"
                     /translation="EPHRSMKFFFYADNLNPSQLKRRAPEHKFLFTAYLPDHSVQFCR
                     WSTQWRCGLASVVPSPGEKVWGAVFEITDEDLKILDEFEDDVPQGAYRHLPVTVITED
                     GEKLLVTTHAANPIGKFKPKEHYIDWVLKGIKQWKLPEECSEQWKAYKPA"
     gene            505..831
                     /locus_tag="PK063_18080"
     CDS             505..831
                     /locus_tag="PK063_18080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S) ferredoxin domain-containing protein"
                     /protein_id="HMZ99014.1"
                     /translation="MPKPKHHILVCTNARPPGHPKPSCGGQGSAQLLMNFNMGLMQRG
                     IMPGEVLVTGSSCLGPCEQGPTVVVYPEGTWYSKVTEADVATILDEHIKGGKPAEKLN
                     PDSIWK"
     gene            1038..1493
                     /locus_tag="PK063_18085"
     CDS             1038..1493
                     /locus_tag="PK063_18085"
                     /inference="COORDINATES: protein motif:HMM:NF013183.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HMZ99015.1"
                     /translation="MIITCSDTRTPDTDTSGQLIQKLLKENGHTIAAYYLVKDEPAQI
                     KARITEGVANDSVQAIIINGGTGISRRDSTFEAVDAMLEKRLDGFGEVFRFLTYQDIG
                     SPAIMSRATAGIINGRVLFSTPGSENAVRLAMEKLILPELGHLVKELTK"
     gene            1714..1887
                     /locus_tag="PK063_18090"
     CDS             1714..1887
                     /locus_tag="PK063_18090"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99016.1"
                     /translation="MKREGSRKPLAPSARPRILKTVIQRGRRRSKTGGLPVSYVKDFD
                     ETRTLLEAMSNEG"
     gene            complement(2141..2575)
                     /locus_tag="PK063_18095"
     CDS             complement(2141..2575)
                     /locus_tag="PK063_18095"
                     /inference="COORDINATES: protein motif:HMM:NF012780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HMZ99017.1"
                     /translation="MATVAQIMNKKPQSVGPTMSLRGAAKKMRTLRVSSLLIKKGKNH
                     VGIVTDTDLVRKGLATNQDVGKLTVEQVMTSPLCTIESNQAVDDAQDMMGDLGVRHLA
                     VTKGGSIVGVVSVRDLLMHYKRYAQSRLADKQVYSEPKIGQD"
     gene            complement(2626..3657)
                     /locus_tag="PK063_18100"
     CDS             complement(2626..3657)
                     /locus_tag="PK063_18100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HMZ99018.1"
                     /translation="MNAVVFHEHGGPGKLQYQEMPMPTIGVDEVLVQVKACALNHLDI
                     WIRQGSPAYPMPLPHILGSDIAGVVHQIGSHVEGVAVGERIYVSPGVGCGKCEQCLAG
                     RDNMCRSYGLIGAMCHGGYADYVKVPARNVRPIPGALSFEQAAAFPLVSVTAWHMLFG
                     LAEVQPGEEVLIMGAGSGVGHMAIQMAKLAGARVLTTVGSEEKVAKAKDLGADEVIIH
                     SREQVNQRVRELTERRGVDVVIEHIGPEVWTQCIDSLAKGGRLVTCGATTGAEVKLDL
                     RYVYSRQLTIKGSYMGSQSELLKAAHLVGEGKLRPVIDRTFPLSEAKGAQEYLLNRKF
                     FGKIVLTVS"
     gene            complement(3866..4795)
                     /locus_tag="PK063_18105"
     CDS             complement(3866..4795)
                     /locus_tag="PK063_18105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HMZ99019.1"
                     /translation="MPGQRRLQFYQADVFTDEPFGGNPVAVFPDADGLTDVELQQIAR
                     EMNLSETVFVFPPTDQAAVVKMRIFTPTQEIPFAGHPVIGTFFVLGTLDRLALREPVT
                     RVLQECNLGLFPVDIHSHDGVIERVVMAQPSPEFLDVIEEPEALFAIARALGITKAAI
                     TESRFPVQVVSTGLPVIIVPVRTLTAVRSIVPDVAAIAELSQQYGANGMMVFSTMTVE
                     QSSTVHTRMFAPLIGIVEDPATGSASGALGAYLVQHGVVDIRPETEITAEQGYEIDRP
                     SRILIQVNSDDDAIQGVMVGGEAVMVVEGVLTF"
BASE COUNT         1108 a         1499 c         1313 g          931 t
ORIGIN      
        1 gggagcctca ccgttcaatg aagttcttct tttacgcgga caatttgaac ccgtcccaac
       61 tcaagcgtcg tgccccggaa cataagtttc tcttcacggc ctatctgcct gaccatagcg
      121 tgcaattctg ccgctggtcg acgcagtggc gctgcggcct ggccagcgtc gtcccgtcgc
      181 cgggagagaa agtctgggga gccgtctttg aaatcaccga tgaagatctc aagatcctcg
      241 acgagttcga ggacgatgtc ccgcagggcg cgtaccggca cctgccggtc acggtgatca
      301 cggaagacgg ggaaaagctc ctggtcacga cccatgcggc caatcccatc ggcaagttca
      361 aaccgaagga acattatatc gactgggtgc tcaagggcat caaacaatgg aagttgcccg
      421 aagaatgcag cgagcagtgg aaagcgtata agccagcctg atagatcgcc acagatcgtc
      481 acttacccat atattgaggt cacgatgcca aagccaaaac atcatatcct tgtctgcacc
      541 aatgcccgac cgccgggcca ccccaaaccg tcctgcggcg gccagggttc cgcgcaactg
      601 ctcatgaact tcaacatggg cctgatgcaa cgcggcatca tgccgggcga agtgctggtc
      661 accgggtctt cctgcctggg cccttgcgag cagggaccga ccgtagtcgt ctatcccgaa
      721 ggcacctggt attccaaagt cacggaagcc gatgtcgcga ccatccttga cgaacacatc
      781 aagggcggga agccggcaga aaaattgaat cccgatagca tctggaagta gctcggatca
      841 tcctcctcgt tgaggatgat caacatgcct ttccagcaag gccgcaggcg actcacacct
      901 ggagggtatc ctcaggggta cgttgaggag cgtgaagagc tgagaacgac gctggaaggc
      961 atgttcgtca ttcaattgct atgagcaccc ctagccacaa agaacacaaa caccacgcgc
     1021 cccgctctgt cggttgcatg attatcacct gcagcgatac ccgcacaccc gacaccgaca
     1081 cgagtggcca gttgatccag aagcttctga aggagaacgg gcacacgatc gccgcctatt
     1141 atctcgtgaa ggatgagccg gcgcagatca aggcgcggat caccgaaggg gtagcaaacg
     1201 actcggtcca agccatcatc attaatggcg gaaccggaat ctcccggcga gattcgacgt
     1261 ttgaagccgt ggatgcgatg ctggaaaaac gtctggatgg attcggtgaa gtctttcggt
     1321 ttttgaccta tcaggacatc ggctcaccgg ccatcatgag ccgggccacc gccggcatca
     1381 tcaacggccg cgtgctcttc tccactcccg gctcggaaaa cgctgtgcgc ctggcgatgg
     1441 aaaaactcat cctccccgaa ctcggtcacc tggtcaaaga actcacgaaa tagcacgtcg
     1501 tcagcgatca gctctcagca atcactcttc agctttgagg tttgctcaga actgactgct
     1561 gtgacctgat gtcactcagt gtgatgaacc cagaagtaag taggaagccg gttttcccgc
     1621 ggcctcatgc aggatgctca aaacggtcat ccggcgaggc cacaaggagt gcggcgactg
     1681 aggcgtaccc gcaggagtgc ttgcaggaat ttcatgaaac gagaaggaag ccggaagccg
     1741 cttgctccct ctgcccgacc caggatactc aaaacggtca ttcagcgagg ccgcaggcga
     1801 agcaaaaccg gaggcctacc cgtaagttac gtcaaggatt ttgatgagac gagaacgctg
     1861 ctggaagcca tgtcgaacga gggctgagga cgttcaaaat ggccgtccag caaggccgca
     1921 ggaagcgcgg cgactgaggc gtaccctggc ggtacgtcgc agggagccgt gcgaccgaga
     1981 acgaagttgg agccagcctt cagcatccca ttgcagaagg atgttcaaaa cggctgtcca
     2041 gcaaggccgc aggcgaagca aaaccggagg cgtaccctca ggggtacgtt gaggattttg
     2101 atgagccgag aacgctgctg gaagccgttt tcaacatcct ctagtcttgg ccgatcttgg
     2161 gttcagaata cacctgctta tccgccagcc tcgattgcgc gtaccgcttg tagtgcatca
     2221 acagatcgcg gaccgacacg acgccgacga ttgacccgcc cttggtcacg gccaggtggc
     2281 gcacgccgag atctcccatc atatcctggg catcatcgac ggcctgattg ctctcgatgg
     2341 tgcacagcgg ggaggtcatc acctgttcga cggtcaactt gcccacatcc tgattggtgg
     2401 ccaaaccttt ccgaaccaga tccgtgtcgg tcacgatccc gacatgattc ttccccttct
     2461 tgatcaagag ggagctgacc cgcagggtgc gcatcttctt cgccgcacca cgaagggaca
     2521 tcgtcggccc gacgctttga ggtttcttgt tcataatttg cgcaacagtc gccatgtcac
     2581 atacctttct gcccgttggg acaagagagc cgataatgaa gccgattacg aaacagtcag
     2641 cacgatttta ccaaaaaact tccgattcaa aagatattct tgcgcacctt tggcctcgga
     2701 gagcggaaag gttcgatcaa tcaccggccg caacttgcct tcgccaacga gatgagcggc
     2761 tttcaacaac tcactctgcg accccatgta cgagcccttg atcgtgagct ggcgcgaata
     2821 cacgtagcgt aagtcgagct tgacctccgc gcccgtcgtc gcaccgcagg tgacgagccg
     2881 tccacctttc gccaatgaat cgatgcactg cgtccacact tccggaccaa tgtgctcaat
     2941 caccacatcc acaccacggc gctccgtcag ttcccgcacc cgctgattga cctgctcacg
     3001 gctgtggatg atgacttcgt ccgcccccag atccttcgcc ttcgcgacct tctcctcgct
     3061 tccgacggtg gtcaagacac gagcgccggc gagcttggcc atttgaatcg ccatgtgccc
     3121 caccccgctg cccgcgccca taatcaacac ctcctcgccg ggctgcacct ccgccaatcc
     3181 gaacaacata tgccaggcgg tgacggagac cagaggaaag gccgcagcct gctcgaaaga
     3241 cagcgcgccg ggaatcggtc gcacattccg ggccggcacc tttacatagt ctgcgtagcc
     3301 gccatggcac atcgccccga tcaaaccata agagcggcac atattgtcac gaccggccag
     3361 acattgttcg cacttcccgc atccgacacc gggagacaca tagatgcgct cgccaaccgc
     3421 aaccccctcc acatgtgagc cgatctggtg caccacgccg gcgatgtccg acccgaggat
     3481 atgcggaagc ggcatcggat aggccgggct cccctgcctg atccagatat ccagatggtt
     3541 caacgcgcaa gccttcacct gcaccaggac ttcgtcgacg ccgatggtcg gcatcggcat
     3601 ctcctgatac tggagctttc ccggcccgcc atgttcgtga aacaccaccg cgttcatatc
     3661 atcctcacct gtcattcatg actacatgac gtttcatgcc gcactgtgat tccgagagta
     3721 caggtcctta accatctccc gcaggacgat caaaacgccc tgtcacaagg ccgcagggag
     3781 cgcggcgact gagtcgtacc cttgtggtac gtcgcaagga gacgtacgac cgggaacgca
     3841 gtgagatggc gttttcatca tcctgctaga aagtgagcac gccctccacg accattaccg
     3901 cttctcctcc aaccatcaca ccctgaatcg cgtcgtcgtc ggagttcacc tggatcaaaa
     3961 tgcgtgacgg gcggtcgatc tcgtacccct gttcggcggt gatctcggtt tccggcctga
     4021 tatccacgac tccgtgctgc acgagatagg cacccagtgc gccactggcg ctgccggtcg
     4081 ccggatcttc cacaatgccg atcaacggcg caaacatgcg agtgtgcacg gtggaggatt
     4141 gctcgacagt catcgtgctg aagaccatca tgccgttggc gccatactgt tgagacaatt
     4201 cggcgatggc cgcaacatct ggcacgatcg aacgcaccgc cgtgagcgtg cgtaccggga
     4261 cgatgatgac cggcaaccct gtcgacacta cctgcactgg aaagcggctt tcggtaatgg
     4321 ccgccttggt gatgcccaga gcgcgggcga tggcgaacaa cgcctccggt tcctcaatta
     4381 catccaaaaa ctccggactc ggttgcgcca tgaccacccg ttcgatcacg ccgtcatgcg
     4441 agtggatatc gacggggaac agccccagat tacattcctg gagcacccgt gtgaccggct
     4501 cccgaagcgc gaggcgatcc aatgtgccca acacgaaaaa agtcccgatg acggggtggc
     4561 cggcgaaggg aatttcctgc gtcggcgtga aaatgcgcat cttgacgact gccgcctgat
     4621 cggtgggagg aaacacaaac accgtttcgg agagattcat ctcgcgggcg atctgctgca
     4681 attcgacgtc ggtcaagcca tcggcatccg gaaacaccgc caccggattc ccgccgaagg
     4741 gttcatcggt aaacacgtcg gcttgataaa actgcaatcg ccgttgcccg ggcatacact
     4801 cctcaaaaag atgctggcgg catgttgccc cgagtcagta ttttttgcaa g
//
LOCUS       DAOQPD010000136         4730 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_11343_length_4730_cov_21.756791, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000136 DAOQPD010000000
VERSION     DAOQPD010000136.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 4730)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4730)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4730
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_11343_length_4730_cov_21.756791"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..610)
                     /locus_tag="PK063_18110"
     CDS             complement(<1..610)
                     /locus_tag="PK063_18110"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HMZ99020.1"
                     /translation="MELGFVGLGKMGMNMVTRLQQGRHRVVAYDRAPDIVKQAEGKGC
                     IGAASLSDLVSKLTAPRAVWVMVPSGAPTEDTIQAISALLQPGDTIIDGGNTRFHDDT
                     RRAAELQKKGIHYVDVGTSGGIWGLQVGYCLMIGGETEPVQRLTPIFTTLAPEQGWAH
                     MGGHGAGHYVKMVHNGIEYSMMQGYAEGFELMAKSDYRLDLGK"
     gene            complement(766..1572)
                     /locus_tag="PK063_18115"
     CDS             complement(766..1572)
                     /locus_tag="PK063_18115"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: protein motif:HMM:NF014021.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HMZ99021.1"
                     /translation="MESHLATSSPQSSPALPSSEELKAELLDIPEPPEMPPAVTPPGY
                     DDALAGAVKYVRAKRGGDLVGIVLVGSGARRAVTAHSDIDLIVLVKGPADGQEMIRVG
                     DRLVDIRYGEHTTVAEDLTYSPRLAPLLRKGRVLYDHEDIAAQLIAKAAQRFRQGPPP
                     ATIHERIRLKAECLHWLGKVEDLRDKPNTAQYLLQLFFEECLSAFFRTRGLWFTAPVD
                     TLRFLASREPALGEVAAQFLSAATLHDRLMAGRRFAETLFRDIPLPPRVD"
     gene            complement(1591..1818)
                     /locus_tag="PK063_18120"
     CDS             complement(1591..1818)
                     /locus_tag="PK063_18120"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99022.1"
                     /translation="MSLHAVSFQQISRILDVTDALGLNREWVEIPLSPETPGIVRKLP
                     NGKLEIVVDADQPFDAWLGTLEQQIRRVQAA"
     gene            complement(1896..2927)
                     /locus_tag="PK063_18125"
     CDS             complement(1896..2927)
                     /locus_tag="PK063_18125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntG family PLP-dependent aldolase"
                     /protein_id="HMZ99023.1"
                     /translation="MIDLRSDTVTKPSPAMREAMARAEVGDDIYGEDPTVNRLQEVGA
                     ALVGKRAALFVPSGTMGNQLSIRAQAEPGREVIVEAQSHVIRYEQGAAAALAGVQLHW
                     VTGTHGLMTAEQVQRAIRPKDPSSIQSALICLENTHNAGGGRVYPLTTIQAIRAVATA
                     HGIPMHLDGARLFNAVVASGVPAAEFAKHFETVTFCLSKGLGAPAGSLIATDDLSMME
                     RLRRFRRMYGGAMRQSGILAAAGLYALDHHIARLSHDHANAKRLAARLQQIPAVTIDP
                     SLVETNILFFEVHSTKFSIPAFVAALKHEGVLINAVGGATCRAVTHLDVSAEAIEEAA
                     DQIAHLLNK"
     gene            3048..4319
                     /locus_tag="PK063_18130"
     CDS             3048..4319
                     /locus_tag="PK063_18130"
                     /inference="COORDINATES: protein motif:HMM:NF019310.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99024.1"
                     /translation="MERWYRSVIRFVQAEPQELRPLAWSFGYFFCLLCGYYILRPVRD
                     EMAIQGGVHNLPWMMTGTFLTLLAVTPLFGWLSARYSRYRLLLAVYLFFIANLIGLYF
                     LMTSGLYIEWVARGFFVWLSVFNLFVVSVFWSFMADLFTPAQGARLFGMIAAGGSTGA
                     LFGPLITTGLTYLFPVPVLMLASAAFLAACIGCIYRLEMWSRSRSLFHRENSGAPLGG
                     GFLAGVRLVWSSPYLLGICGYLTFLTMTATFLYFEQVRLVAQQFDTPEARTRLFSMLD
                     FATNILTWLTQLLLTNHVVARFGLAAALLFLPAVSLLGFLGIALWPGLVVYVSFSVLR
                     RVGEYALSKPAREVLFTVVSREEKYKAKNFIDTAISRAGDASTGWLVSGLKALSVTTA
                     QIAWVLVPLMVLWGWLGRWLAAQQRKQIGPG"
     gene            4501..>4730
                     /locus_tag="PK063_18135"
     CDS             4501..>4730
                     /locus_tag="PK063_18135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HMZ99025.1"
                     /translation="MMVEVPVKLYLDKVLKTAREAVRPTSLLSGPIRDKALRGMATAL
                     AEAEEPILAANETDVDAVGKSMTGYENRERVR"
BASE COUNT          845 a         1373 c         1472 g         1040 t
ORIGIN      
        1 tttttcccag gtcgaggcga tagtcacttt tcgccatgag ttcgaatccc tcggcgtacc
       61 cttgcatcat gctgtattcg atgccgttgt gcaccatctt gacgtagtga cctgcaccgt
      121 gcccgcccat gtgggcccag ccctgttccg gcgccagcgt agtgaagatg ggcgtcagcc
      181 gctgaaccgg ttcggtttcc ccgccgatca tgaggcaata gccgacttgc aatccccaga
      241 tcccgccgct ggtacccaca tcgacataat gaatgccctt tttctgtagt tcggcggcgc
      301 ggcgcgtatc gtcatggaag cgggtgttgc cgccgtcgat aatcgtatcg cccggctgca
      361 gcagcgcgct gatggcctga atggtgtctt ccgtcggggc tcccgacgga accatgaccc
      421 ataccgcgcg gggagcggtg agtttggaaa caaggtcgct cagggaggcc gcgccgatgc
      481 agcccttgcc ttctgcctgc ttcacgatat cgggtgcacg atcgtatgcc acgacgcggt
      541 gacggccctg ctgcaggcgc gtcaccatgt tcatgcccat tttgccgagt ccgacgaatc
      601 caagttccat aggtcaccct ctctggtgaa gaccgatatg tgatgactag tgcggagccg
      661 gccaagaacg gagtggcgct ccagtggttc ggtgcaggtc tgatgctatc acggtcggac
      721 acccacgcaa gcgctgtcgc cttggcacgg ggtgatggag ccctgttagt ccacgcgggg
      781 tggaagggga atatcgcgaa acagggtctc ggcaaatcgt cggccggcca tcaatcgatc
      841 gtgaagggtt gccgcgctga gaaattgggc agccacctcg ccgagtgccg gctcgcggga
      901 cgccaggaac cggagggtgt ctaccggtgc cgtgaaccag agccctcgag ttcgaaaaaa
      961 tgcagagagg cactcctcga aaaagagctg cagcagatat tgcgcggtgt tgggtttgtc
     1021 gcgcaggtct tcgacctttc cgagccagtg caggcattcg gctttgaggc gaatgcgttc
     1081 gtgtattgtc gctggcggcg ggccctggcg aaatcgttgc gccgccttgg cgatcaactg
     1141 cgccgcaatg tcctcatggt cgtagagcac gcgtcctttg cgaagcaggg gtgcgagacg
     1201 aggagagtag gtgagatctt cggcgacggt ggtatgttca ccatagcgga tatcgaccag
     1261 ccggtctccc acccggatca tttcctgccc gtcggccgga cccttcacca ggacgatgag
     1321 atcgatatcg ctgtgcgccg tcaccgcgcg tcgggcgccg gatccgacga gaacaatacc
     1381 caccaggtcg ccgccgcgtt tcgcgcggac gtatttcacc gcgccggcga gggcatcgtc
     1441 gtagccgggc ggcgtcaccg cgggaggcat ctccggtggt tcgggaatat ccagtaactc
     1501 agccttcagc tcctccgagg acgggagcgc gggggaagac tgcggggaag aggttgccag
     1561 gtgtgattcc atgtctatcc ttcaacgcgg tcaggcggcc tgtacacgcc gtatctgttg
     1621 ctcgagggtg ccgagccacg cgtcgaacgg ctggtcggca tcgacaacaa tctcaagctt
     1681 tccattagga agtttgcgaa cgatgccggg agtttccggc gagagaggaa tttccaccca
     1741 ctcgcgattc agccctagcg catccgtcac gtcgaggatg cgactgatct gttgaaacga
     1801 cacggcgtga agcgacactc aatcctctct actcttgttg gcattgtagg tggggggaca
     1861 gagactgtca acgtgaggcg caaggcctgc tcggtctact tgttgagcag atgcgcgatc
     1921 tgatcggcgg cttcctcaat cgcctccgcc gacacgtcga gatgggtcac cgcgcgacaa
     1981 gttgcgccgc cgacggcatt gatcagcacg ccctcatgct tgagggccgc cacaaacgcc
     2041 gggatggaaa atttcgtgct atgcacctcg aagaacagaa tgttcgtttc gacgagggat
     2101 ggatcgatgg ttacggctgg aatctgttgc agccgggccg caagccgttt ggcgttggcg
     2161 tgatcgtgac tgagtcgcgc gatgtgatgg tctaaggcgt agagacccgc cgcggcgaga
     2221 attccagact ggcgcatggc gcctccatac atgcgacgaa atcgccgaag gcgctccatc
     2281 atgctgagat cgtccgtcgc aatcagcgac ccggccggtg ccccgagtcc tttggagagg
     2341 cagaaggtca ccgtttcgaa gtgcttcgcg aattccgcgg ccggcacgcc cgaagccacg
     2401 accgcattga acaggcgggc cccgtcgaga tgcattggta tcccatgggc agtggcgaca
     2461 gcgcgaatgg cctgaatggt tgtcagcggg tagacccggc cgcctccggc gttgtgcgta
     2521 ttctcaagac aaatgagtgc gctctggatg ctagagggat ctttcggtcg gatggcgcgc
     2581 tgcacctgct cggccgtcat gagcccgtgc gtgccggtca cccaatgaag ttgtacgccg
     2641 gccaacgccg ccgccgcgcc ctgctcataa cgaatgacat gtgactgagc ttcaacaatc
     2701 acttcacgtc ctggttcagc ctgcgctcga atggacagtt ggttgcccat cgtgcccgag
     2761 ggcacgaaga gtgcggcccg tttgccgacg agtgcggcac ccacttcctg gagacgattg
     2821 acggtggggt cttcgccata aatgtcatca cccacctcgg cgcgggccat ggcttcacgc
     2881 atagcggggc tgggtttggt gaccgtatcg ctccgaagat cgatcatgga tgggcctcaa
     2941 tcaggagtgg agtgtggttc ttcaggacga accgcgggtg cattctagca aaaattcttc
     3001 ttgccggtgt gccggggcct gctacactgg ccccaattcg gagccccatg gagcgatggt
     3061 atcggtcagt catccggttt gtgcaggctg agccgcagga actgcggccg ttggcctggt
     3121 cgttcggata ttttttctgt ctcctctgcg gctactacat tcttcgcccc gtgcgcgatg
     3181 aaatggcgat ccagggcggg gtgcacaatc ttccctggat gatgacgggc acgtttctca
     3241 ccttgctcgc tgtcacgccg ctgttcggtt ggttgtctgc gcggtattcc cgctatcgat
     3301 tgctcctcgc cgtctatctc ttctttattg ccaatctcat cggcctgtat tttttgatga
     3361 cgagcggtct gtacatcgaa tgggtggcgc gcgggttttt tgtctggctc tcggtattca
     3421 acctgttcgt cgtgtcggtg ttctggagtt tcatggccga cctgtttacg ccggcgcaag
     3481 gcgcgcgcct cttcggaatg attgcggcag gcggcagcac cggcgcattg ttcggtcccc
     3541 tcatcacgac cggcctcacg tatctcttcc cggtgccggt gttgatgctg gcctcggctg
     3601 cgtttctcgc ggcctgcatc ggatgcatct acagattgga aatgtggagc cgcagccggt
     3661 ctctgtttca ccgggagaac agcggagccc cattgggcgg aggctttctg gctggtgttc
     3721 gcctcgtgtg gtcgtcgccg tatctgctcg gtatctgcgg ttacctgacc tttttgacga
     3781 tgacggctac cttcttatat ttcgaacagg tgcgtctggt ggcgcaacag ttcgatactc
     3841 cggaagcccg cacgcgcctg ttctccatgc tcgacttcgc caccaacatc ctcacctggc
     3901 tgacgcagct cttgctcacc aaccatgtgg tggcccggtt cggcctggct gcagccttac
     3961 tgtttctgcc ggcggtgagc ctcctcgggt ttttaggcat cgccctctgg ccgggcttag
     4021 tcgtgtacgt cagcttttcc gtactgcgtc gagtagggga atatgcgctt tcgaaaccgg
     4081 cgcgcgaggt gctgttcaca gtggtcagtc gcgaggaaaa gtataaggcg aagaacttta
     4141 tcgatacggc gatctcgcgc gcgggggatg cctcgaccgg ctggctggtc tccggcctta
     4201 aagcgttgag cgttaccacg gcacagatcg cctgggtcct ggtcccgctc atggtcctct
     4261 ggggttggct aggccgatgg cttgcggcgc aacaacgcaa acagattggg ccgggttagg
     4321 cctcccttcc tggcctctgt cgcctccaga gatgggacca cgctgctttg actcacaaaa
     4381 aaatcgcatg gtatagtccg gcgcggatcg ttgaaggcct gtaatgatgc tgtcctgacg
     4441 attcccggca ccctgtgacg attcaccgga cgcccactca ccagctcacc aattggggac
     4501 atgatggttg aagttccagt taagctctac ctcgataaag tattgaagac ggcgcgtgaa
     4561 gcggtacgtc ccacgtcgct tctttccggt cccatacgag ataaggcgtt gcgcggtatg
     4621 gcgacggctc tggcagaagc ggaagagccc atcctggcgg cgaacgaaac ggatgtggac
     4681 gcggttggaa agtcgatgac gggatatgaa aaccgtgaac gtgtgcggga
//
LOCUS       DAOQPD010000137         4601 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_11908_length_4601_cov_21.873515, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000137 DAOQPD010000000
VERSION     DAOQPD010000137.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 4601)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4601)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4601
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_11908_length_4601_cov_21.873515"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..2458)
                     /locus_tag="PK063_18140"
     CDS             complement(<1..2458)
                     /locus_tag="PK063_18140"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: protein motif:HMM:TIGR02093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HMZ99026.1"
                     /translation="MSDGLNELRQQYGCGPVQFYGTDDALYERHLVFDNVIVPEKASP
                     REQFEAVARTLRDVISQRWLLTEETYLEKNPKRVYYLSMEFLLGRSLLNNAVNSRLAA
                     LMLEAMKKKSHVDPALIEMEPDSGLGNGGLGRLAACFLDSMATLEMPGMGYGLRYEYG
                     IFKQTIKDGWQIEQADNWLRRPDPWEVARLDEAVEVKLNCSFEFRAGVLQPVIGRPSI
                     LLGIPFDRPIIGYGGKTINTLRLWAAATPDYFNFQQFSRGDFVGALAETLTAETLTRV
                     LYPDDSTYKGQGLRFLQEYFLVACSLADLVRRCRHANNDWSALPEKVAIQLNDTHPAM
                     AVPELMRILLDEAHLGWEQAWDLTQRTLAYTNHTLLPEALEKWPLRWFEVLLPRVAEI
                     ICEINRRFLDSLGTQFPNDRSRFDRVSLIEDGTDRKVRMANLAIVGSHSTNGVSAIHS
                     KLLRTRVVPDLAEIFPTRFNNKTNGVTPRRWLLLCNPGLTQLITDAIGDGWITDLSQL
                     SRLKPLAEDKGFQEGFRKAKREAKMRFADWVKATTGEVVDPDTIFDSQIKRIHEYKRQ
                     LLNALHIVVLYNRLRENPHLEFAPRTFFFAGKAAPAYALAKLIIKFINNLAGTIKGEP
                     AVGRYLRVVFVPDYCVSVAERLIPASDVSEQISTAGYEASGTSNMKFMMNGALTIGTR
                     DGATIEMAEEAGEENLFLFGLSAEEVANSRGWYNPQWHYENEPETRRALDLIFSDHFS
                     RHEPGVFNPIREALVTHGDYYMHLADLKSYSETQERLVRLYADSQGWANKAILNVASS
                     GKFSSDRTIAEYARDIWRVTP"
     gene            complement(2455..>4601)
                     /gene="glgX"
                     /locus_tag="PK063_18145"
     CDS             complement(2455..>4601)
                     /gene="glgX"
                     /locus_tag="PK063_18145"
                     /inference="COORDINATES: protein motif:HMM:TIGR02100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004133 - glycogen debranching enzyme
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="glycogen debranching protein GlgX"
                     /protein_id="HMZ99027.1"
                     /translation="EMEQKRVIQQGESFPLGSTVYPAGVNFSLFSKNSTLVELLLFDH
                     VGDAKPAAVIALDLRWNRTYHYWHVFVPGIQDGQIYGYRVFGPFEPHRGLRFDSSKLL
                     LDPYGKAMAMPDGYSRVNASVPGDNCATAMKSIVADPSKYDWEGDIPLKRPFAKTVIY
                     ELHVRGFTRHPSSGLSHETRGTYRGLIDKIPYLQDLGVTAVELLPVFQFDEQDAPWGL
                     VNYWGYSPISFFVPHHGYSSRKDHLGPMDEFRDMVKALHRAGIEIILDVVFNHTAEGD
                     RAGPTLCYRGLENAAYYMLEEDRSRYADYTGTGNTLNANQPIVRRLILDSLRYWVESM
                     HVDGFRFDLASILSRDEDGRPLKNPPILWDIESDPCLAGTKLIAEAWDAAGLYQVGSF
                     IGDSWKEWNGQFRDDVRSFMKGDNGTVRRVARRLLGSPDLYGHEEREPEQSLNFVTCH
                     DGFTLNDLVSYNHKHNEANGEDNRDGTDFNLSWNCGVEGPTDDPSIEHLRNRQVKNFL
                     ALTLLSIGTPMVLMGDEVRRTQRGNNNTYCQDNDISWFDWTRLRKHADIHRFVKFLLL
                     LRLRSPLARGESSLTLNEILCRARIDWHGILLNRPDWNDESHSLALTAGTLDGRFLVH
                     VIVNAYWEPLAFELPGAAKSEQGWRRLIDTGLDSPDDICDGSDAPLVPGDSYLTQPRS
                     VVVLFAFKTGSVGQDISSPGNRNVWSTSAEAV"
BASE COUNT          920 a         1368 c         1324 g          989 t
ORIGIN      
        1 atggtgtaac tctccaaatg tcccgagcat attccgcaat cgtgcggtcg ctggaaaact
       61 tgccggagct ggcgacattc aaaatggctt tgttcgccca gccctgcgag tcagcgtaga
      121 ggcgcaccag tctctcctgc gtctcgctgt acgacttgag gtccgccagg tgcatgtaat
      181 agtcgccgtg cgttaccagc gcctcgcgaa tcggattgaa gacccccggc tcatgacggc
      241 tgaagtggtc agaaaagatc aggtccagcg cccgacgcgt ttccggttcg ttctcatagt
      301 gccactgcgg attgtaccag ccgcggctat tggcgacctc ttcggcgctg agaccaaaga
      361 gaaagagatt ctcctctccg gcctcctcag ccatttcgat cgtcgcgccg tcgcgtgtgc
      421 cgatcgtcag cgcaccgttc atcatgaact tcatgttgct cgtcccgctg gcttcatagc
      481 cggctgtcga gatctgttcg gacacatcgc tggcgggaat caggcgctcg gccactgaga
      541 cacaataatc cggcacaaac acgactctca gatacctgcc cacggcgggc tctcccttga
      601 tggtgccggc cagattgttg atgaacttga tgatgagctt ggcgagcgcg taggccggcg
      661 ccgccttgcc ggcgaagaag aacgtgcgcg gcgcgaactc gaggtgtgga ttctcgcgca
      721 gacgattgta gagcaccacg atatgcaagg cattgaggag ttgtcgctta tattcgtgaa
      781 tgcgtttgat ctggctatca aagattgtgt cggggtctac cacctcaccg gttgtcgcct
      841 tgacccaatc cgcgaaccgc attttggctt cgcgtttggc cttgcgaaag ccttcctgaa
      901 accccttgtc ctcggcgagc ggcttcaatc tggacaattg gctgaggtcg gtaatccagc
      961 catcgccgat cgcatcagta ataagctgtg tcaatccggg attgcagagc agcaaccacc
     1021 ggcggggcgt gacgccgttg gttttgttgt tgaaacgtgt cggaaatatc tcggcaagat
     1081 ccggcacaac ccgcgtccgc aacagtttgg agtgaatggc gctgacaccg ttcgtgctgt
     1141 gtgagccgac gatggcgaga ttggccatgc gaaccttccg gtctgtgccg tcctcgatga
     1201 gactgacacg gtcgaagcgt gaacggtcgt tggggaactg tgtccctagc gagtcgagaa
     1261 aacgccggtt gatctcgcaa atgatctccg cgacccgcgg gagcaagact tcaaaccatc
     1321 tgagcggcca tttctccaat gcttcgggca agagggtatg gttcgtatac gcgagcgtgc
     1381 gctgcgtcag gtcccaggct tgctcccagc caagatgcgc ctcatcgagc aggatccgca
     1441 tgagttctgg cacggccatc gccggatgtg tgtcgttcag ttggatcgcc accttttccg
     1501 gcaaggcgct ccagtcgttg tttgcatgcc ggcagcggcg gacaagatcg gcaagcgagc
     1561 aggcgacgag gaaatactcc tgcaggaagc gtagtccctg tcccttatac gtcgaatcat
     1621 cgggatacag cacgcgtgtg agcgtttcgg cagtgagcgt ttccgccaac gctccaacaa
     1681 aatcaccgcg gctgaactgc tgaaagttaa agtagtccgg cgtggcggcg gcccagagtc
     1741 gaagcgtatt gatggtcttc cctccgtagc cgatgatggg ccggtcgaac gggatgccga
     1801 gcagaatcga cggtcggccg atgacgggtt gcagtacgcc cgcgcggaat tcaaatgaac
     1861 agttcagttt gacttccacc gcttcgtcta gccgtgctac ctcccaaggg tcaggacgcc
     1921 gcaaccagtt gtcggcctgc tcgatttgcc agccgtcttt gatcgtttgc ttgaagatgc
     1981 cgtattcata acgcagaccg taccccatgc ccggcatctc cagcgtcgcc atcgagtcca
     2041 ggaagcaggc cgccaggcgg ccaagaccgc cattgccgag ccccgagtcg ggctccatct
     2101 cgatgagggc cggatcgaca tggctcttct tcttcatggc ttcaagcatg agcgccgcga
     2161 gtcgagaatt gacggcattg ttcaggagcg atctccccag gagaaattcc atggagaggt
     2221 agtacacccg cttcgggttc ttctccaggt acgtctcttc ggtcagcagc cagcgttgcg
     2281 aaatgacgtc tcggagggtc cgtgccactg cctcaaactg ctcgcgcggg ctggccttct
     2341 cgggaacaat gacattgtcg aacacaagat gccgttcgta gagtgcgtca tccgttccgt
     2401 agaactggac cggcccgcat ccatattgtt ggcgaagctc gttcagacca tcactcatac
     2461 cgcctccgcc gaagtactcc agacgtttcg gttgcctggg gaagatatgt cttgcccgac
     2521 actgcccgtt ttgaacgcga ataagaccac caccgaccgg ggttgtgtca gatagctgtc
     2581 acccggaacg agcggcgcat cggacccgtc acagatgtca tccggcgagt ccagaccggt
     2641 gtcgatcaga cgacgccagc cctgctctga cttcgccgcg cccggcagtt cgaatgccag
     2701 gggctcccag taggcattca cgatgacatg gacgaggaac cgcccgtcaa gagtgccggc
     2761 cgtcaaggcc aggctgtggg attcgtcgtt ccagtccggc cgattgagca ggattccatg
     2821 ccagtcgatc cttgcccggc aaaggatctc attcagagtc agactgctct cccctcgcgc
     2881 tagtggactc ctcaagcgca acaagaggag gaacttcacg aagcggtgga tgtcggcatg
     2941 cttcctgagt ctcgtccagt cgaaccaact gatgtcattg tcttggcaat aggtgttgtt
     3001 gttcccgcgc tgtgtgcgcc gaacttcgtc gcccatgagt accatcggcg tgccgatgga
     3061 cagaagcgtc agcgccagga agtttttcac ctgccggttg cgcaaatgct cgatggacgg
     3121 gtcgtcggtc ggaccttcca ctccgcaatt ccagctcagg ttgaagtcgg tcccgtcccg
     3181 gttgtcctcc ccgttcgctt cattgtgttt gtggttgtag gacaccaggt cgttcagcgt
     3241 gaatccgtcg tgacaggtca cgaaattgag gctctgctcg ggttctcgct cctcgtgccc
     3301 atagagatca ggactgccta acaatcgtcg ggccacccgc ctcaccgtgc cgttgtctcc
     3361 cttcatgaag ctgcggacgt catccctgaa ttggccgttc cactctttcc aactgtctcc
     3421 aataaacgag ccaacctggt acaggcccgc cgcgtcccag gcctccgcga tcagcttcgt
     3481 tccggctagg cacggatccg attcgatgtc ccacaggatg gggggattct tcaacggccg
     3541 gccatcctcg tcgcgggaga ggatcgaggc cagatcgaag cgaaagccgt ctacgtgcat
     3601 cgactccacc cagtagcgca ggctgtcgag gatcaaccgg cggacaatcg gttgattcgc
     3661 gttcaaggtg ttcccggtgc cggtatagtc ggcatagcgt gaccggtcct cctccagcat
     3721 gtaatacgct gcgttctcca ggccgcgata gcagagcgtc gggccggcgc ggtctccttc
     3781 cgccgtatgg ttgaacacga catcgagaat gatctcgatg ccggcccgat gaagcgcctt
     3841 gaccatgtcg cgaaactcgt ccatcgggcc caagtgatct ttgcgggaac tatacccgtg
     3901 gtgcggcaca aagaatgaaa tggggctgta gccccagtag ttgacgaggc cccacggagc
     3961 gtcctgttcg tcgaactgga atacgggcag caactccacg gcggtcacac cgagatcctg
     4021 caggtacgga atcttgtcga tcaatcctcg atacgtgccg cgcgtttcgt gagagagacc
     4081 ggaactggga tggcgggtaa acccgcgcac gtgcaactca tagatcacag tcttggcaaa
     4141 cggccgtttc agcgggatat ctccctccca gtcgtatttg ctaggatcgg cgacgatgct
     4201 cttcatcgcc gttgcgcaat tgtcacccgg tacggacgcg ttgacgcggc tgtagccgtc
     4261 cggcatggcc atcgcctttc cgtatgggtc aagcaacagt ttacttgagt caaaccgcaa
     4321 tccacggtgc ggttcgaacg gtccgaatac ccgatagccg taaatctgac cgtcctgaat
     4381 accgggcacg aagacatgcc aatagtggta tgtccggttc caccgcagat cgagggcaat
     4441 caccgccgcc ggttttgcat cgcccacgtg atcgaacagc agcaattcca caagggtact
     4501 gttcttggag aacaggctga agttgacccc cgcgggatag accgtggagc cgagaggaaa
     4561 actttcaccc tgttggatca cccgtttctg ctccatttcc a
//
LOCUS       DAOQPD010000138         4534 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_12210_length_4534_cov_24.386470, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000138 DAOQPD010000000
VERSION     DAOQPD010000138.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 4534)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4534)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4534
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_12210_length_4534_cov_24.386470"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..696
                     /locus_tag="PK063_18150"
     CDS             <1..696
                     /locus_tag="PK063_18150"
                     /inference="COORDINATES: protein motif:HMM:NF021207.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02710 family CRISPR-associated CARF protein"
                     /protein_id="HMZ99028.1"
                     /translation="GGQKPLYRALAELALGYGLWEQFQYRQAWEKLKTSLKALDMASI
                     WGGPPGLKALLPLIKANSGFLEKMVLDPAEVKEGVVLDLLAHAHRRAHGDHDPERAMV
                     ALVRALEACAQRQLFKQYKIKTWDVQPDQLPEALRDTCRTSYLDDVDGKYKLPLQSQW
                     RTLAGLGDQMGQAFLRDWPKMKPLLDAANHAVLGHGFEAVKGERVQQLSDMVMKLTGV
                     SESSLPKFPVLSL"
     gene            1137..1538
                     /locus_tag="PK063_18155"
     CDS             1137..1538
                     /locus_tag="PK063_18155"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: protein motif:HMM:NF013782.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047617 - acyl-CoA hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbgC/FadM family acyl-CoA thioesterase"
                     /protein_id="HMZ99029.1"
                     /translation="MDIRIYYEDTDCGGVVYYANYLKYFERARTHYLEERGLSVAGLR
                     DQGTQFVVVHAELDYRSPGRYGDTLVIDTTLTDASQASFTFAHVLRERTSGRIVVEGS
                     AKLVTVDEQLKPKRLDKLTLAALQGPPHTRH"
     assembly_gap    1793..1892
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(2113..3423)
                     /locus_tag="PK063_18160"
     CDS             complement(2113..3423)
                     /locus_tag="PK063_18160"
                     /inference="COORDINATES: protein motif:HMM:NF013862.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HMZ99030.1"
                     /translation="MTSLEAFTSHPTVEAAVRDAQTATEGKHLSDIVDDHGFQYVDFV
                     MEGGGVLGIALTGYTYVLEQAGIRFLGIGGTSAGSINALMIAALGPPEEAKSERLLHI
                     LAGMPMASFIDGDQDARDFSQSALGKVGMMKLLLKAMQVVDNLSDDLGLNPGTAFYDW
                     LTAELLKVGVRTNADLAKRLQTVPAGLHLRPDRTDRQLTEADTIGRLIMVAADITTET
                     KVEFPRMAELYWAKPDEVNPAYFARASMSIPLFFHPFRVNNCSQDRAKWKDVASYDGV
                     PPDTVMFMDGGIMSNFPINLFHQPYHVPASPTFGAKIGTDRAQPAVIDKPSQLLGAVF
                     DAARHTLDFDFISRNPDYKHLVAMIDTGDHNWLNFSMEDTDKIDLFARGAAAAAEFLQ
                     TFNWTKYKSIRKGIADAFLASNTNNGGSLKLAGNSQRLVALSSH"
     gene            complement(3463..3972)
                     /locus_tag="PK063_18165"
     CDS             complement(3463..3972)
                     /locus_tag="PK063_18165"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99031.1"
                     /translation="MAGKIFSALLASGFPNSIRLCGKVMVSEENADARSMSQPPEGRA
                     SGRPAKGNVVALDLLFPFVYGGVLAASLWWIWMTLGRPFHPGWIAAPLLVTTIADWLE
                     GLMLLAQLRHYMSPNQQYAESLLIRLSGCATIIKLWLTSGLYVTLAGLVLNLLFTFPG
                     RRLASDAAE"
     gene            complement(4190..>4534)
                     /locus_tag="PK063_18170"
     CDS             complement(4190..>4534)
                     /locus_tag="PK063_18170"
                     /inference="COORDINATES: protein motif:HMM:NF015669.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="META domain-containing protein"
                     /protein_id="HMZ99032.1"
                     /translation="AERNRWELAHWGNQAIPYEDDGEAVILAFKDGKVSGQAGCNRYA
                     AAITFGPKTGEVSVSHGITTRMACQPKRMEFEAAFIRAFEASTRYRLDGESLLFESAI
                     AQPLEFYRRPPE"
BASE COUNT          991 a         1192 c         1313 g          938 t
ORIGIN      
        1 ggcggacaga aaccgttgta tcgcgccctg gctgaacttg cactgggata tggactctgg
       61 gagcagttcc agtatcgtca ggcctgggaa aagctgaaga cgtcattgaa agccctcgac
      121 atggcgtcga tctggggtgg gccgccgggt ctgaaagcat tgctgccgtt gatcaaggcc
      181 aatagcggct ttttggaaaa gatggtgctc gaccccgccg aggtcaaaga aggtgtcgtg
      241 ctcgatctgc tggcgcacgc gcatcgccgc gcgcatgggg accatgatcc tgagcgggcc
      301 atggtggcgc tcgtccgcgc gttggaggcc tgcgcgcagc ggcagttgtt caaacagtac
      361 aagatcaaaa cgtgggatgt gcagcctgat caattgcctg aggccttacg ggacacctgc
      421 cgcacctctt atctcgacga tgtcgacggc aagtataagc tgcctttgca aagccagtgg
      481 cggacgttgg ccggcctcgg cgatcagatg gggcaggcgt ttctccgcga ctggccgaag
      541 atgaaaccac tgctagatgc cgccaatcat gcggtgttgg gccatgggtt cgaggcggtc
      601 aaaggggagc gggtgcagca gctctccgat atggtcatga agcttaccgg cgtgagtgaa
      661 tcctcgttgc ccaagttccc cgtcctcagt ctctagttaa ccgtcgttcg tgaagcgtga
      721 agcgtatctc gttggaccag acagccggat ggaaaagata cgaaattttc gcgatcttga
      781 aatatggaag ctgggcaaga atatcgtgct cgatgtctat cgagtgacca aggcgttccc
      841 caaggaagag atctacggat tagtgtcgca aatgcgtcgc gcagcgatat cgattccctc
      901 gaataatagc agagggattc aatcggaaac acaatgcgga ataccgacag tttctctatg
      961 tcgcgcttgg gtcttgcgct gaattggaaa cccacgtgga aatcgctcag gacctcacat
     1021 tcatcacggt tgttcagcga gacgagctgt tggagcaact tgaccacgag tcgaagatgg
     1081 tcagaagtct tatcaaacgg ctttgacgag atacgcttca cgagatacgg aagacgatgg
     1141 acatccgcat ttactacgaa gacaccgact gcggcggggt ggtgtactac gcgaattatc
     1201 tcaagtactt tgaacgggcg agaacgcact atctcgaaga gcgaggattg tcagtcgcag
     1261 ggctgcgtga tcagggcaca cagttcgttg tggtgcatgc cgaactggat tatcggtcac
     1321 ctggacggta cggcgacacc ttagtgatcg acaccacgtt gacggatgcg agtcaggcgt
     1381 cgttcacctt tgcgcatgtg ttgcgggagc ggacgagcgg gcgtattgtg gtggaaggat
     1441 cggccaagct ggtgacggta gacgagcagt tgaaaccgaa gcggctcgac aaactcaccc
     1501 ttgctgcgtt acaaggacct ccacacacga ggcactaatg gataaactcg gcacatggct
     1561 ggcggtgacg ggcgtggcga tcggtttcgt cgtcctcgca tggctgctct tctctgataa
     1621 tccttccgac aagaaaaaga aaaaacctta gttcggatcc tgcgacggcg cgggtccggc
     1681 ttcgcattcg tcactcgccc atcaatttct taatcgtgtc ttccattccc tccgcccata
     1741 cgcgatagcc gcgttcacca gggtgcagcg cgtcgggcat catctcttca ggnnnnnnnn
     1801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnaataattg cagagctcca aacagcaggg
     1921 cgggcaggaa agagacggat agtgtattgc ggtgcataga ggtccccaca agatcctgcc
     1981 ccatgtgtat cgcaggatca cgaggagatc aactgtgcct agtcgcgcat tgcggtacag
     2041 ggatggcgtg aaggaggcga tgttgactcc gcctcctcca gactgccggt attgtccctg
     2101 gctcagcacg acctagtgag agctgagtgc gacgagcctc tggctattgc cagcaagttt
     2161 cagagatcct ccattgttcg tattgctcgc aagaaaggcg tcggcaatac ctttgcgaat
     2221 ggatttatat ttcgtccaat tgaatgtctg caaaaattcg gcggcggctg ccgcgccgcg
     2281 agcgaagagg tcgatcttgt ctgtgtcctc catgctgaag tttaaccagt tgtgatcgcc
     2341 ggtatcgatc atggccacca ggtgcttgta gtccgggttt cgcgagatga aatcaaaatc
     2401 cagggtgtga cgagcggcat cgaacacggc gccaagtagt tgtgagggtt tgtcgatgac
     2461 ggccggctgc gcgcggtcgg tgccgatttt cgcgccgaat gtgggagaag ccggcacatg
     2521 atagggctga tgaaacagat tgatgggaaa gttggacatg atgccgccgt ccataaacat
     2581 gaccgtgtca ggagggacgc catcatatga cgccacgtct ttccacttcg ccctgtcctg
     2641 ggagcagttg ttgacgcgga atgggtgaaa gaagagcgga atcgacatgg aggcgcgcgc
     2701 gaaataggcg ggattgacct cgtcaggttt ggcccaatac agttccgcca tcctgggaaa
     2761 ctcgaccttt gtctcggtcg taatatcggc ggccaccatg atgagtcggc caatcgtgtc
     2821 tgcttcggtc agctgcctgt ctgtccggtc tggacgaaga tgcagccctg ccggcaccgt
     2881 ttgtagccgc ttggccaaat ccgcattggt tctcactccg actttcagga gttcggcggt
     2941 cagccagtca tagaaggccg tgccaggatt cagtcccaag tcatcagaaa ggttgtcgac
     3001 gacctgcatg gccttcaaaa gcagtttcat catcccgacc tttcccaaag cggactgaga
     3061 aaagtctcgc gcatcctgat cgccgtcgat gaagctcgcc atcggcatcc cggccagaat
     3121 gtgtaacagc cgttcactct tggcttcctc cggcgggcct aaggccgcaa tcatcagcgc
     3181 attaatcgat cccgctgagg ttccaccgat gccgagaaag cgaatgccgg cttgctccaa
     3241 cacataggtg tatccggtca gcgcaatgcc gagtacccct ccgccttcca tgacgaagtc
     3301 cacatattgg aacccgtgat catcgacaat atcggacagg tgctttcctt cagtggccgt
     3361 ctgagcgtcc cggacggccg cttctacggt gggatggctg gtaaacgctt caaggctggt
     3421 catagaagcc tccatagaca ggtcccgggc gggaacgccg gattattcag cggcatcact
     3481 cgccaggcgc cggcccggga atgtgaatag caagttcaga acaagtccgg ccagggttac
     3541 gtagaggccg ctggtgagcc atagcttgat gatcgtggcg caaccggaaa gccggatcaa
     3601 caggctctcg gcatattgct gattcggcga catgtagtgg cgaagttgcg ccaggagcat
     3661 gaggccctcc aaccaatccg ctatcgtggt caccaggagc ggtgcggcaa tccagcccgg
     3721 atggaacggt cgccccagcg tcatccagat ccaccacagg ctcgccgcaa ggacccctcc
     3781 atatacaaat ggaaagagga ggtccagagc aaccacattt cctttggccg gtctccccga
     3841 ggctctccct tccggtggct gagacatgga acgggcatct gcattctcct cagaaaccat
     3901 gaccttgccg cacagccgta tggaattcgg gaatccggaa gcgaggagcg cgctgaagat
     3961 cttgccagcc atgataggga ttccaagttc acccatgtat cgagcaagag cggtgcccgg
     4021 tgggtttatg gaatggatgt aaacgcagcg gcctattttg agagcaggga ccaatgccag
     4081 cggtcagaat cgatgtgctt ctcctgagtg tcgtatcaca agcgatacga tgtcgtatcg
     4141 gaagggatac gcgaaggaca gactcgatgt gaaatcagag agagatgggt tattccgggg
     4201 ggcgtcgata gaactccagc ggctgagcaa tggcgctctc aaacaacagg ctttccccat
     4261 cgagtcgata ccgggtggag gcttcaaagg cacggatgaa cgccgcctca aattccatgc
     4321 gcttgggttg gcaggccatg cgcgtggtga tgccgtgcga taccgagacc tcgccggtct
     4381 tgggtccgaa cgtgattgcc gccgcatacc gattacatcc agcctgaccc gacactttcc
     4441 catccttgaa ggcgaggatc accgcctctc catcgtcttc atacggaatg gcctggttgc
     4501 cccagtgggc aagttcccaa cgattgcgtt cagc
//
LOCUS       DAOQPD010000139         4390 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_12888_length_4390_cov_15.338870, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000139 DAOQPD010000000
VERSION     DAOQPD010000139.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 4390)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4390)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4390
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_12888_length_4390_cov_15.338870"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..406)
                     /locus_tag="PK063_18175"
     CDS             complement(<1..406)
                     /locus_tag="PK063_18175"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99033.1"
                     /translation="MVPSLIEITLEDLAKDVWLPLNLDFIQQTGELIEEAEPEGSPAE
                     YAPPDPEVAVAPAALTYPSASTSVEGPSSAQPVPPPQGGAQAATLDPATSTRPVSSGR
                     SSALIRDFIMPYQPVIESQRALEPLLTVVKILE"
     gene            complement(480..932)
                     /locus_tag="PK063_18180"
     CDS             complement(480..932)
                     /locus_tag="PK063_18180"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99034.1"
                     /translation="MSDRQTEACSTENALHARWAFDVTPGRERHVALQLQELGCTDVE
                     RPTKGYVIAHCDPTAVPVIKRLSGVVRALPLLDTDLFEDRSNVEPLLAKVADVVQVSS
                     GPYAQMTGIVRALEGEDVLVDVSLMGRVVRVRAKSRHVSVMPLPEPWR"
     gene            complement(974..1432)
                     /locus_tag="PK063_18185"
     CDS             complement(974..1432)
                     /locus_tag="PK063_18185"
                     /inference="COORDINATES: protein motif:HMM:NF013618.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HMZ99035.1"
                     /translation="MNHSCVVAAANRYAVTVQILEAIILVESEGDPHAVNVNRDGKGD
                     RRGPLSFKQATDLVAELWKAGANFDVGIAQINSVHMRQYKIDPVHFLDPCINIQWAAF
                     VLRQKINEYQETWTAVGRYNGSRNIAGYSWKVYRALERLAGIRRARGLLR"
     gene            complement(1573..3528)
                     /gene="traN"
                     /locus_tag="PK063_18190"
     CDS             complement(1573..3528)
                     /gene="traN"
                     /locus_tag="PK063_18190"
                     /inference="COORDINATES: protein motif:HMM:NF018666.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraN"
                     /protein_id="HMZ99036.1"
                     /translation="MKRMLIGICLAICLVCGVVEVRADCSGIDDPYLKAKCEVEGQKA
                     SGLVGAGILAPNMTKVPQYSGSPGCVTAGCSGAAEEKYYDDPGSLSAAGGAAASSDER
                     YSKIQQSRIDRDGWDLRTSSPVTTAQSTAATLPTDSIMTESCSVVNMCTSYTEGAGVT
                     GTCQVPGGSRQTCLKIRNPTLLPNACTVPGIPSPPYTSETEVNGCKDLEAAGASGLAA
                     LVTTTCLDGAARDLKCSQPYATVLTGGTSGFNAHDHAPGMAMGNFTIESAFPIWDGTR
                     WVVGLNVTGNSAGEDKYGCTNVGSVKTGPYVLTPANPTASGNGSPAYCNSKCSCFGYP
                     MTFTMGAFSPTGPLSWQVPFTFTYESHSIAVMVTGTFLDTYSVAPLTGCFQEEQTWDV
                     TSTAGDTCGEYRDKGCNQVSSRCASVQPGTGYCLMYENTYKCPGPSECSTTQPITQCT
                     KCGKPDSPVPFCVDTSTPPNENLALAATWLAMTKNVEEDWDPDRLRIFTGKRSTCDFS
                     TIGRSLINCCDSDPDKLIGKCSEEEIALARDKHDRKAHLIGTHCVDKGSFLVGSVCLR
                     KEEVYCTMKSELGRMVQEQGRVQLGMTWGSADAPQCDGFTVDQFSALNFQAIDFTEWY
                     KNVSANIDPAVITKEMATKICTYTGTC"
     gene            complement(3545..4036)
                     /locus_tag="PK063_18195"
     CDS             complement(3545..4036)
                     /locus_tag="PK063_18195"
                     /inference="COORDINATES: protein motif:HMM:NF014019.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HMZ99037.1"
                     /translation="MKILTVDVIPGHTYRYFQALIQIETVGIASWRDAVVRFTDFWGG
                     RAKTYDSPIVHATQSMVNRLAQSAAALGADLIIGFDIQIHQVTARYWGWGMAQIIMRG
                     TPIQFMDRDALGTILAGELSPFVARDQSARHPPDGNSLGEAVGMDEMTVPSLDTARLG
                     TRR"
     gene            complement(4043..>4390)
                     /locus_tag="PK063_18200"
     CDS             complement(4043..>4390)
                     /locus_tag="PK063_18200"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99038.1"
                     /translation="SPVATTTVPAKLDVPMPVPQRVIEAKVESPRTKPDADKGWLRRF
                     LDGFRGGNGQNAELVSPPLASGMSGKASTGRPLLPAVDGEVMAAPMNTLTISIDADAP
                     KKAEVSPSDTEKR"
BASE COUNT          937 a         1411 c         1097 g          945 t
ORIGIN      
        1 cctcgagaat tttcaccacc gtgagcagcg gctccagtgc gcgctggctc tcaattaccg
       61 gttgataggg catgatgaaa tcccgaataa gtgcggacga ccggccagac gacaccgggc
      121 gtgtcgaggt ggcgggatcg agtgtggcgg cctgtgcgcc tccctgagga ggcggcaccg
      181 gctgggcaga ggacgggccc tccacagaag ttgatgcact gggatatgtc agggccgcag
      241 gagcgacggc cacctcagga tcaggcggtg catactctgc tggactaccc tcgggctcag
      301 cttcctcgat cagctcccca gtttgttgaa tgaagtccaa attgagcgga agccacacgt
      361 ctttagccag atcctctagg gtgatttcga tcaggctcgg caccacaagg ggagttgctt
      421 ctccggtatg aactcttgca gactcgcccc gccaagctcc ccacaatctc ccgagcatgt
      481 cacctccacg gttccggtaa cggcatcacg ctcacatgcc tcgatttagc cctgactcgt
      541 accacccgcc ccatcaaact cacatccacc agcacatcct cgccttccag ggctcggacg
      601 atgcccgtca tctgcgcata tgggcccgaa ctcacctgca ccacgtcggc caccttggcc
      661 aggagtggtt caacattgct acggtcctcg aagaggtcgg tatccagcaa gggaagcgct
      721 cgcaccactc cagacagccg cttgatcacg ggaacggccg ttggatcaca gtgagcgatc
      781 acatagccct ttgtcggacg ttccacgtcc gtgcacccca actcctggag ctgcaaggcc
      841 acgtgtcgtt cacggcctgg cgtgacatca aacgcccacc gtgcatgtaa cgcattctca
      901 gtggagcacg cctctgtttg tctgtcgctc acagttcctc cttttgaaaa ccgctccacc
      961 tcaccccgcg gactcatcgc agcaagccac gggctcgtct gatgcctgcg aggcgctcca
     1021 atgcccgata caccttccag ctgtagcccg cgatgttgcg actgccgttg taacggccta
     1081 cggctgtcca cgtttcttgg tactcgttga tcttctgccg caagacaaac gccgcccatt
     1141 ggatattgat acaaggatcg agaaaatgga ctggatcaat tttgtactgc cgcatgtgca
     1201 cgctattgat ctgtgcaatc cccacatcaa aattcgcccc cgccttccac agttcagcaa
     1261 ccagatccgt cgcttgcttg aaagaaagtg gtcctcgccg atcccccttc ccgtcccgat
     1321 tcacattcac cgcatgcgga tccccttcac tctccactag aataatggct tccaatattt
     1381 gcacggtcac cgcgtagcga ttcgccgccg ccacaacaca actgtggttc acataccaaa
     1441 accggtccgg aggcatctcc gccgcaacac tgtccggcaa gacaccgaga cataccaccg
     1501 caagacagaa ccacgtcgaa cggcgacttg tcggcctgga gaatgcaccc agaggcccac
     1561 catacccccg tcttaacagg tgcctgtgta ggtgcatatc ttcgtcgcca tttccttcgt
     1621 gatcacagcc gggtcaatat tcgctgaaac atttttgtac cattcagtga aatctatcgc
     1681 ctggaagttc aaagcgctga actgatcgac cgtaaatccg tcacactggg gcgcatccgc
     1741 tgatccccag gtcatgccca actgcacacg gccttgttcc tgcaccatcc gaccgagctc
     1801 ggatttcata gtgcagtaga cctcttcctt tcggaggcac acactgccga ccagaaagga
     1861 gcctttatcc acacaatgtg tcccaattag atgagccttt cgatcgtgtt tatccctcgc
     1921 tagcgcgatc tcctcctcag agcatttccc aatcaattta tcggggtccg aatcgcagca
     1981 attgattagt gatcgcccga ttgtgctgaa atcacaggtg ctccttttgc ccgtgaagat
     2041 acgcagacgg tccggatccc aatcttcttc gacattcttg gtcatcgcca gccaggtggc
     2101 cgctaacgcc agattctcat tgggtggcgt actggtatcc acgcaaaacg gcacaggact
     2161 gtctggtttc ccacacttcg tgcattgagt aatcggttgc gtcgtcgaac attccgacgg
     2221 tcccggacac ttgtaggtgt tctcgtacat caagcaatat cccgtccccg gctgcaccga
     2281 tgcgcagcga gagctgactt gattgcagcc cttgtctcga tactcgccac aggtgtcccc
     2341 ggccgtggac gtgacatccc aggtttgctc ctcttgaaag catcccgtta agggcgccac
     2401 gctgtacgta tcgagaaagg ttcccgttac catgaccgca atcgaatgcg actcgtaagt
     2461 aaatgtaaac ggaacttgcc agctgagcgg gccggtggga ctgaaggcgc ccatcgtaaa
     2521 cgtcatggga tacccaaagc atgagcactt gctattgcag taggccggcg agccatttcc
     2581 agaggccgtc gggttcgccg gagtcaacac gtaaggcccg gtcttcaccg agccaacatt
     2641 tgtgcagccg tatttgtctt ctccggcgga attgccagtg acgttcaagc cgaccaccca
     2701 tcgagttcca tcccagatag gaaacgccga ttcgatcgta aaattgccca tggccattcc
     2761 cggcgcatgg tcgtgcgcat tgaatccaga agtccccccg gtcagcacgg tggcatacgg
     2821 ttgagaacac ttgagatctc gcgcagctcc atcgagacag gtcgtagtca ccagtgcggc
     2881 gaggccactg gcgccagccg cttctagatc cttgcaccca ttgacctccg tctcagaggt
     2941 atagggaggg ctgggaattc caggaaccgt acacgcgttc ggtagcaggg tggggttgcg
     3001 aatcttgagg caggtctgcc gtgagccccc aggcacttgg caggtccccg tgacgccagc
     3061 cccttcggtg taactcgtgc acatattcac cacggaacag ctctccgtca tgatggaatc
     3121 ggtcggcagc gtcgctgccg tcgattgcgc cgtcgtcacc gggctactag tccgtagatc
     3181 ccacccatct cggtcaatcc tgctctgttg gattttcgag taacgctcat cggagctcgc
     3241 cgccgcaccg ccggccgcgc tcaaactgcc gggatcatcg taatacttct cttcagcagc
     3301 cccagagcac cctgccgtga cacaacccgg cgatcctgag tactgcggca ctttggtcat
     3361 gttcggcgcc agaatacctg caccgactaa tcctgaggcc ttctgcccct ctacctcaca
     3421 cttcgctttg aggtacggat cgtcaatccc actgcaatct gcgcgtacct ccacaacacc
     3481 acacaccaaa cagatcgcga ggcaaatccc tatgagcatg cgcttcatca cagacagcct
     3541 ccccctatcg acgcgtgcct aaccgagccg tatccaatga gggcaccgtc atctcgtcca
     3601 tccctaccgc ttctcccagt gaatttccgt ccggcggatg tcgagcggac tggtcccttg
     3661 caacgaaggg ggacagttca ccggccaaaa tcgtcccaag cgcgtcacga tccataaact
     3721 gaatcggcgt tccccgcatg atgatttgtg ccatacccca cccccagtat cgtgccgtca
     3781 cctgatgaat ctgaatgtcg aagccaatga tcaggtcagc tcccaatgcc gcagcgcttt
     3841 gcgcaagcct attcaccatg ctctgagtcg catggacgat cggactgtca tacgtcttcg
     3901 cgcgccctcc ccagaaatcc gtgaatcgga caacggcatc ccgccaggaa gcgatcccga
     3961 cggtctcgat ctgaatcaat gcctgaaaat accgataggt atgtccggga atgacatcca
     4021 ccgtaagaat tttcattcgg acctatcgct tttcggtatc agatggtgac acctcagcct
     4081 tcttcggagc atctgcgtcg atactgatcg tcaatgtgtt catcggcgcg gccatcactt
     4141 ccccatcgac agccggaaga aggggacgtc cagttgaagc ttttccggac atcccagaag
     4201 ctagaggagg agacaccagt tccgcgtttt gcccattccc cccacggaag ccatccagaa
     4261 aacgtcgtaa ccatcctttg tccgcgtcgg gcttggttcg aggcgattcg accttagcct
     4321 ctatcaccct ctgaggaacg ggcatcggca catccagttt ggcagggaca gtggtcgtcg
     4381 ccactggact
//
LOCUS       DAOQPD010000140         4339 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_13149_length_4339_cov_24.030112, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000140 DAOQPD010000000
VERSION     DAOQPD010000140.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 4339)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4339)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4339
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_13149_length_4339_cov_24.030112"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(243..1304)
                     /locus_tag="PK063_18205"
     CDS             complement(243..1304)
                     /locus_tag="PK063_18205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99039.1"
                     /translation="MRERRWETAGRLTFQEILAVGERLGALGLKPAHPAKDVICYVED
                     WAVDSPEAFDQLDHWATEDVTLLHIREAWQGDFFLLAGGYHTVYQRFQDVGTYCSISH
                     PWRTKPGLRFHHPTSMFWLGFRHNHAFIRVRLHTQEVVTPGETREDARRAEWVDERRA
                     IFLDAIAMLDLPVETSVDKGSLVLTPADPATPFFCSWPDAFGPCQFEYNSLDAYEFLV
                     PASRLAATMASQPAGVRAYLTGFSDQALDAFAAVQPGAKTVYRCSVHCALGELPEVLE
                     TIAPQGRLYSTLCEFQTQELMPEGEDASAIIGIVGTAGGFQLEARLNRAPLPEEHMAG
                     WLERLLGMTVVYAPLPPFM"
     gene            complement(1350..2000)
                     /locus_tag="PK063_18210"
     CDS             complement(1350..2000)
                     /locus_tag="PK063_18210"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99040.1"
                     /translation="MIAQGCRIAGQVCIAVGLALLWGCAGTGEMVSLNVQPQQPFVQS
                     GQPEPLKIVIEPFEDRRADKTKIGQRTHLGGGVTNFNVSGGSPGVTIAEALAEALRWR
                     GWNRRGWDARVVQSGVGVSGADIVIGGEIVDFSANAKSRVFNTKLTGESRLVIRAKNM
                     SDESSTQRNLQGEQSKLVFWFTSEDVENLMSGLLQDGIERFIADTKIEGRALKSAK"
     gene            complement(2134..2763)
                     /locus_tag="PK063_18215"
     CDS             complement(2134..2763)
                     /locus_tag="PK063_18215"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99041.1"
                     /translation="MASPGADSLLTSDELRLVGDRDLFRSKERTILKVQALLTTLQAG
                     LQADLAHMTLLFPPEFDPAKAQSVKGERLEQCPYQYLDYPKHFHGDDKFTFRSLCWWG
                     HHLVFAMIVEGGQAKQCKKNFFDRFHQLAGQGLELSLAPTLWEWKRGEGYTLPITHDR
                     KAQLAAVLSGRAWFKIARFVPLDSPALREGRLPEIGRETFRSLFPLLSP"
     gene            complement(2843..3223)
                     /locus_tag="PK063_18220"
     CDS             complement(2843..3223)
                     /locus_tag="PK063_18220"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99042.1"
                     /translation="MAQRFQSGAFVQQCFAVHPLCLSLKRIDDDGRLVIACTSCRMMH
                     LMTPDQVVGRVAAVPLGGEVESPKAVPTARESLEDCLRAHPVSVTIRELDVIRDQVGL
                     RCGECRRIFDMQVSAFESLQKSQS"
     gene            complement(3347..3682)
                     /locus_tag="PK063_18225"
     CDS             complement(3347..3682)
                     /locus_tag="PK063_18225"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99043.1"
                     /translation="MTLLLDPQQRSTRPAWHVFFSHTLRYVLAPLLFISSGFFTANFI
                     VSAHYTWPRTSRVFVLTLTLLILAYEFIYKDRTIQSNAPDRAFNAVLYSCMIPYALGV
                     LMMLALAKL"
BASE COUNT          981 a         1305 c         1245 g          808 t
ORIGIN      
        1 aggcgattgt caaacgaaga gaggaatcag gcgatgaaat tggaaggcac gatcgagtca
       61 caataggcat gtcgcgggtc acgctacagc aaaaggatct agcattcacg gtttagccgg
      121 ccgctcaaca cgggcatcca gcaaggccgc aggggagaaa gaaccggagg cgtacccgct
      181 gcggtacgtc gaggattctt tcgacctgag aacgcagctg gggtccgtgt tcagcggccg
      241 gactacatga agggagggag gggcgcatag actaccgtca tgcccaatag tcgctccagc
      301 caaccggcca tatgctcctc gggtagtgga gcgcgattga gccgggcctc cagttgaaac
      361 cctccggctg tgccgactat cccgatgatg gccgacgcat cttctccctc gggcatcaat
      421 tcctgcgttt ggaactcaca gagggtactg tagagacggc cctgtggcgc gatggtctcc
      481 aacacttcgg gcaattcacc caacgcgcaa tgtaccgaac agcggtaaac cgtcttcgcg
      541 cccggttgca ccgcggcaaa ggcatccaat gcctggtcgg aaaatcctgt gagataggct
      601 cgcacaccgg ccggctgcga cgccatggtc gcagccaatc gactcgccgg cacaagaaat
      661 tcataggcgt cgagtgagtt gtattcgaac tgacaggggc cgaaggcatc cggccaggaa
      721 caaaaaaacg gcgtcgccgg gtctgcgggc gtcagcacca ggctgccctt gtcgacggat
      781 gtctccaccg gcagatccag catggcgatg gcatcaagaa agatggcccg ccgctcatcc
      841 acccattcgg cccgccgtgc atcctcccgg gtttctcccg gcgtcaccac ttcctgcgta
      901 tgcagacgca cccggataaa ggcatggttg tgacgaaacc ccagccagaa catggaggtg
      961 ggatgatgaa accgcaaccc gggtttcgtg cgccagggat gactgatgga gcagtaggtg
     1021 ccgacatcct gaaagcgctg atagacggtg tggtaaccgc ccgccagcag aaaaaaatca
     1081 ccctgccagg cttcgcggat gtggaggagg gtgacatctt ccgtggccca atgatcgagc
     1141 tgatcgaagg cctcgggaga gtcgacggcc cagtcctcca cgtagcagat cacgtctttg
     1201 gcgggatgag ccggcttgag gcccaaagcc cctagacgct cgccgaccgc caggatctcc
     1261 tgaaaggtca gccggccggc ggtctcccag cggcgttcac gcacaacgct cctccgcggt
     1321 ccgcgcgccg ctgtcgaatc tggcgggcct cacttggccg acttcagcgc gcggccctca
     1381 atcttcgtat cggcgataaa ccgctcaatg ccgtcctgca aaagaccaga catgaggttc
     1441 tcgacatctt cgctggtaaa ccagaacacc agcttgcttt gttcaccctg gagattgcgc
     1501 tgcgtgctgc tctcatcgga catattcttg gctcgaatca ccaggcgact ctcgcccgtc
     1561 aatttcgtat tgaacacgcg gctcttggca ttggccgaaa aatcgacaat ttctccacca
     1621 atgacgatat ctgcgccgga gacgcccacg cccgactgca ccacgcgcgc atcccatcca
     1681 cgacggttcc agccccgcca ccgcaaggcc tcggccaagg cttcggcgat cgtcacccct
     1741 ggcgagcctc cgctgacatt gaaattcgtc accccgccac ccaaatgggt gcgctggccg
     1801 atcttcgtct tgtccgcgcg acgatcctca aacggttcga tgacgatttt cagcggctcc
     1861 ggctggccgc tctgcacaaa cggttgctgc ggttgcacat taagcgacac catttctccg
     1921 gttccggcac agccccagag cagcgccaac cccaccgcaa tacagacctg acccgcgatt
     1981 cgacatccct gtgcaatcac acatgcctcc tgtcagtatg tggccttact aaaacgcgcc
     2041 cagtctaccc aactcgcagc cggatgacaa acgggaaagg gctggtttca gcaggaaaat
     2101 tcgccggtgg tccacgtcaa aacatgaagc tggttagggg ctgaggagag ggaagaggct
     2161 tcgaaaggtc tcccgcccga tctccgggag gcgtccttcg cgtaaggccg gcgaatccaa
     2221 cggcacaaac cgggcgatct tgaaccaggc ccgcccggac aatacggcgg ccaattgagc
     2281 cttccggtcg tgggtgatcg gcaacgtgta gccctcgccc cgcttccatt cccataacgt
     2341 gggcgccagc gaaagctcca agccctggcc cgccaactgg tgaaaccggt caaagaagtt
     2401 ctttttgcac tgcttcgcct gaccaccctc gacgatcatc gcaaacacca gatggtgccc
     2461 ccaccagcat aacgagcgga aggtaaactt gtcatcgccg tgaaaatgtt tcggatagtc
     2521 cagatattga taggggcact gttcgagacg ttcccctttc acggattgcg ccttggctgg
     2581 gtcaaactcg ggaggaaaca acaatgtcat gtgagccagg tccgcctgta accccgcctg
     2641 aagcgttgtc agaagtgctt gtaccttcag gatcgtccgc tctttggaac ggaacaggtc
     2701 gcgatcgccg accagtctga gctcatccga cgtcaacaac gaatcagcgc cggggctagc
     2761 catgggatcc ctctctgtca ttgtttactg agatcagtgg ccggagtgag acaggtgtgt
     2821 ggtcacgggt gatgcgtgac ggtcacgatt gggatttctg aagagattca aacgctgaga
     2881 cctgcatgtc aaatatgcgc cggcattcac cacagcgcaa tcccacctgg tcgcgaatca
     2941 catccaattc cctaatggtg acggagacgg gatgggcacg cagacagtct tccagtgatt
     3001 ccctcgccgt cggtacggct ttgggactct ccacttcgcc gccaagtggc acagccgcaa
     3061 ctcgccccac gacctgatca ggcgtcataa gatgcatcat gcgacaggac gtgcaggcga
     3121 tcaccaggcg tccgtcgtcg tcaatccgct tgagcgacaa acataaggga tggacggcga
     3181 agcattgttg gacaaaggcg ccgctttgaa accgctgtgc catagccacc tattgaagga
     3241 tgagggacgc cggtgcctgc tggctcttca gaacgtgatc gataggatgt tcacgacacg
     3301 gttcagcgaa gcgagacaac cgccgtgggt ggttttcaac atcctttcac agcttggcca
     3361 acgccagcat catcaacaca ccgagagcat acggaatcat acaggaatac agcaccgcat
     3421 tgaatgcccg atccggggca ttcgactgaa tggtgcgatc tttgtaaatg aactcgtagg
     3481 caagaatcag cagggtgagg gtcaggacga agacccggct cgtgcgaggc caggtgtaat
     3541 gagcgctcac gatgaaattt gccgtaaaga atccgctgga aatgaagagc agtggcgcga
     3601 gcacataccg cagcgtgtgc gaaaagaaca cgtgccaggc cggcctggtc gaacgctgct
     3661 gcggatctaa tagcagggtc atgacccgac aggcgcgggt tggctggacg gagacgaagg
     3721 ggcttgtttg gcttgctctg cagcagtttt gcaggttttg caaatacgcg ggcgctgttt
     3781 gaggaaactg atttttccgc tcgcgaggca gctatagtgg acgaattcgt cgcagaccgc
     3841 gcaccgtgac catcccccgc gaagcatcgt cttgtcgcgg tacaggccct ggttacacac
     3901 cttgcagttg cggggttcaa tccccaacag catcggctcc cagtcaccac cgccattgcg
     3961 aagaatattc atggggcgga agtataacga aggggtcgaa gaaaaaacaa ggagggaggg
     4021 gtaggagggc ggccctagtg gtccccccat gatcgcgcaa cgcgcggcct gggaaggccc
     4081 tcgttggacg cgctcactct gggaggacca ccagaccgcc ctcctaacaa gatagacgta
     4141 agaagaaggc gcacgatcgg aatgtgcccg tcccatgcgc agtgaagcgc caccaggcga
     4201 gtccctcggt aagagacgta ggcatgatcg tatgcgcaag ccacgcgttc cacgagcagg
     4261 aggatgctgg cagaagtcag cttcattgac accccttcaa cccttttgct actctccgcc
     4321 ggttcccatc cattcatcg
//
LOCUS       DAOQPD010000141         4235 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_13645_length_4235_cov_30.153828, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000141 DAOQPD010000000
VERSION     DAOQPD010000141.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 4235)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4235)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4235
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_13645_length_4235_cov_30.153828"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..>4235)
                     /locus_tag="PK063_18230"
     CDS             complement(<1..>4235)
                     /locus_tag="PK063_18230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="multicopper oxidase domain-containing protein"
                     /protein_id="HMZ99044.1"
                     /translation="RSVRSGPKKLSQRRSQAAWKLLLGVMLPSVCVGAFQVASAAAPE
                     LHAAAHNQPAWAEQLKGQTIVEDAQEGHVERTAMMERQHQRIMDKINEQLVHDAEVQR
                     TGGQYNNVNMLHQYGAGNQDLLLMSNSGAEPVSSMGGKCPASAPVRSYDVSAINVEIT
                     LNMWLDFYPGYMYTLTENIDKVRAEETKNKEARDKEGYDPGGVMNGLQNQFIQPLVLR
                     GNQGDCVKLTLRNQLEGDEEVSLNIHGSSMVMSATGQPATTTNPDSIAGKGKAVEMEW
                     YIPPTQQEGSRQFHSYSNDRELTVMGLFGSFVIEPKGSEYLEPLGTGDPKPTKSGWQA
                     IIKNGSGPDFREFVLFYHEVGDEAFRPLNKKGDFIPQRDPLTDVYRPVARALNYRSEP
                     FGVDNMQTQHEYFGFEDESMAYSAYTFGDPATTIPRSYLGDPAKFRLVHGGSEVFHSH
                     HPHGGSIRWPRSPRAIDEMPLWHAAKNGPVKYPVIRTKSDRVDVEVIGPSETMDLETE
                     CGSGLCQQLAGDFLFHCHVAHHYIAGMWGYWRVYNTIQQGANHNDVMPDLLELPDRKG
                     RIKVGVTSDELIGKTVDWFGKQFKIIEKGKTDWKADPAIVTIKDWVDMQFPPQGLPGH
                     KKDERDQTRSYDASVLNWGWQGTRAVTEPENTVPNPRYQSAHPGERLPIVFEPLTGKV
                     SWPHLKPHFGRRVPFSKSHNPSPWLEMIHLDEDGQPSSYPAKPGENGRWSLCPENAGS
                     KKYNVHFIHTPMMLADKQGDTAAIMDEGGLIYVLHEEEAAIRKNNDLKFPLVVRSNIY
                     DCVDWMLTSEWDDDDFGNFHASKVNTHWHFLQFDNQSSDGVITGFSNEQSVRPFTMLE
                     KKTDKGLPLPLNTTFTKAGKKGDRVITLKNAAQYHPGIEILIGADNVGGNEVGRIQSI
                     KGNEITLVRPLKNDHPVKDIVTVEFVRQRFWVDSDVGTVFWHDHALGRITWGHGGFGT
                     MLVEPVGSTYHNPKTGAPIRSGPLADIRTAEPVGYGVNGSFRELLVQLNDSVPHTINI
                     VTAGNPPGQPVEVALEAGKTISFPIPDHIKMTPMPFLNGGTHTTGGGLNFRAEPISGR
                     LKANPDTSKLFSSAVHGDPYTPMVRAYLGDTVVFRLLQTMTNESMVWTLSGHTYLTER
                     YAGDANRKNSIHVGIAERYDLVVPQAGGPRLQAGDYIHFNGRSSKFSEGAWGILRVLD
                     KDVTDLQKLPAGYSGRNEIPKAPAVCPADAPVKSFNVSAIDFPSMKLNPKAPDAIEVD
                     FERTIQMVNPDAKIYVLDEDVATVASGLQPMPLTLRANVGDCLKVKLSNKMKQGRASF
                     SALGLAFDPKDSLGANVGNNPGEQTVAPGESRVYTFYADPFIGETASLVWDWGNVMTN
                     PRNGLYGGIVIGPKGATYRDPKTGADISTKNSW"
BASE COUNT          796 a         1345 c         1180 g          914 t
ORIGIN      
        1 ccagctgttc ttggtggaga tatccgcacc ggtcttcgga tcgcgatagg tcgccccctt
       61 gggcccgatc acgataccgc catacaaccc gttgcgcgga ttggtcatga catttcccca
      121 atcccacacc agagacgcag tctctccgat gaacggatcg gcatagaacg tgtacacgcg
      181 gctctcaccc ggagcgaccg tttgctcgcc cggattgttg cccacgttgg cacccaggga
      241 atccttcgga tcaaaagcca gacccagcgc cgagaacgac gcacggccct gcttcatctt
      301 gttgctcaac ttcaccttga gacagtcccc gacgttcgcg cgcaacgtca gcggcatcgg
      361 ctggaggccg gacgccaccg tcgcaacatc ctcgtccaag acgtaaatct tggcatcagg
      421 attgaccatc tggatggtcc gctcgaagtc gacctcgatg gcatccggag ccttcgggtt
      481 caacttcatc gacgggaaat cgatcgccga cacattgaaa ctcttcaccg gcgcatcggc
      541 aggacatacc gccggggcct tcggaatttc gttccggcca ctgtatccgg caggcaactt
      601 ttggagatcc gtgacgtcct tatcgaggac gcgcaagata ccccaagcgc cttccgagaa
      661 cttggaggaa cggccgttga agtggatgta gtcacccgcc tgcaagcgtg gtccgcctgc
      721 ttgcggcacc accaggtcgt atcgttcagc gataccgaca tggatcgagt tcttccggtt
      781 ggcatcgccg gcataccgct cggtcagata ggtatgaccg gacaacgtcc agaccatgct
      841 ttcattggtc atcgtctgca acaaccggaa cacgaccgta tcccccaggt aggctcgcac
      901 catcggggtg tacggatcac cgtgtacggc gctgctgaag agcttcgacg tatccggatt
      961 cgccttcagg cgtccgctga tcggttccgc tctgaagttg agaccgccgc ccgtcgtgtg
     1021 ggtaccgccg ttcaggaacg gcatcggcgt catcttgata tggtctggaa tcgggaacga
     1081 aatcgtcttc cccgcttcca gggccacttc caccggctgc cccggaggat tacccgccgt
     1141 cacgatgttg atcgtgtgcg gcacgctatc gttcaactgc accaacaact cacggaagct
     1201 gccgttcacc ccgtagccca caggctccgc ggtgcggatg tccgccaacg gaccgctccg
     1261 gatcggcgca ccggtcttcg gattgtgata ggtcgatccg accggctcaa ccagcatcgt
     1321 accgaatccg ccgtggcccc aggtgatccg gcccaacgca tggtcgtgcc agaacacggt
     1381 gcccacatcg gaatctaccc agaaccgctg ccggacaaat tccaccgtca cgatatcctt
     1441 cacaggatga tcgttcttca acggccggac gagcgtgatc tcgttgccct tgatcgactg
     1501 gatccgtccg acttcattcc caccgacgtt atccgcgccg atgagaattt cgatgcccgg
     1561 atgatactgc gcggcgttct tcagggtgat cacgcgatcg cccttcttcc ccgccttcgt
     1621 aaacgtggtg ttcaagggca agggcaagcc cttgtccgtc tttttttcca gcatggtgaa
     1681 cgggcgcacc gactgttcgt tcgagaagcc ggtgatcacg ccgtccgacg actggttgtc
     1741 gaactgcagg aagtgccaat gggtgttgac cttcgacgcg tggaaattgc cgaagtcgtc
     1801 gtcatcccat tcgctggtca acatccaatc gacgcaatca tagatgttgg agcgcacgac
     1861 caatgggaac ttcaggtcgt tgttcttccg aatggccgct tcctcttcat gcaacacata
     1921 gatcaacccg ccttcatcca tgatggccgc ggtgtcgcct tgcttgtcgg cgagcatcat
     1981 cggcgtatgg atgaagtgca cgttgtattt cttcgagccg gcattctccg ggcacaggct
     2041 ccagcgtccg ttctcacccg gcttggcggg ataggaactc ggctggccgt cctcgtcgag
     2101 atggatcatc tcaagccagg gcgagggatt gtggctcttc gagaacggca cgcggcgacc
     2161 gaaatgcggc ttcaagtgcg gccaggagac cttaccggtc aacggctcga acacaatcgg
     2221 caaccgttcg ccgggatggg ccgattgata ccgcggattc ggcaccgtat tctcaggctc
     2281 cgtcaccgca cgagtaccct gccaccccca attcagcacg ctggcgtcat aggagcgtgt
     2341 ctgatcgcgc tcgtcctttt tgtggccagg cagaccctgc ggcgggaatt gcatatcgac
     2401 ccagtccttg atcgtcacga tggccgggtc ggccttccag tcggtcttgc ccttctcgat
     2461 gatcttgaac tgcttaccga accaatcgac agtcttgccg atcagctcgt ctgacgtcac
     2521 acccaccttg atgcggccct tgcggtccgg caactccagc aggtccggca tcacgtcatt
     2581 gtgattcgcg ccctgctgaa tggtgttgta gacacgccag tagccccaca tgcccgcgat
     2641 gtagtgatgc gccacgtggc agtggaacag gaagtctccc gccaactgct ggcagagacc
     2701 ggatccacac tcggtttcca ggtccatggt ctcggacgga ccaatgactt ccacgtcgac
     2761 ccggtcggac ttcgtccgga tcacaggata tttcacgggc ccgttcttcg ccgcatgcca
     2821 caggggcatt tcgtcgatgg ctcgcgggct ccgcggccaa cgaatcgatc caccgtgcgg
     2881 atggtgcgag tggaacactt cggaaccacc gtgcaccaac cggaatttgg ccgggtcacc
     2941 gaggtagctg cgcggaatgg tcgtggccgg atcgccgaac gtataggcgc tgtaggccat
     3001 cgactcatct tcgaagccga agtattcgtg ctgcgtctgc atgttgtcga cgccgaacgg
     3061 ctcgctccga tagttcaagg cacgggccac cggacgatag acgtcggtga gcggatcgcg
     3121 ctgcgggatg aagtcgccct tcttgttcaa tgggcggaac gcttcgtcgc cgacttcatg
     3181 atagaacagc acgaactccc ggaagtccgg gccgctgccg ttcttgatga tcgcctgcca
     3241 gccgctcttg gtcggcttgg gatcgccggt tcccagcggc tcgaggtatt cagatccctt
     3301 cggctcgatc acgaaggaac cgaagaggcc catgacggtc aactcacgat cgttgctata
     3361 cgaatggaac tggcggctgc cctcctgctg cgtcgggggg atataccatt ccatctccac
     3421 cgctttgccc ttgcccgcaa tgctgtcggg gttggtggtc gtggccggct gtcccgtcgc
     3481 cgacatgacc atgctggaac catggatgtt caagctgact tcttcgtcac cttccagctg
     3541 attgcggagc gtcagcttca cgcaatcgcc ttgattgccg cgaaggacca atggctgaat
     3601 gaactggttc tgcaatccgt tcatgacgcc gcccggatcg tacccttcct tgtcacgcgc
     3661 ttctttgttc ttggtctctt cggcacgaac cttgtcgatg ttctcggtca gcgtgtacat
     3721 gtagcccgga tagaaatcga gccacatgtt caaggtgatt tccacattga tcgccgacac
     3781 gtcgtagctg cgaaccggcg cgctggctgg gcacttcccg cccatcgagg agacgggctc
     3841 ggcgccgctg ttcgacatca ataacaaatc ctggttaccg gcgccgtact ggtgcaacat
     3901 gttgacgttg ttgtattggc cgcccgtccg ctgcacttca gcatcatgga ccaactgctc
     3961 gttgatctta tccatgatcc gctggtgctg gcgctccatc attgcggtgc gctcgacatg
     4021 gccttcctgc gcatcctcga caatggtctg ccccttcaat tgctcagccc atgcaggctg
     4081 attatgcgcg gccgcatgca gctccggcgc cgccgccgag gccacctgga acgccccgac
     4141 acagaccgat ggaagcatca cccctaagag aagcttccac gccgcttggg acctgcgctg
     4201 actgagtttc ttaggcccgc tacgtaccga tctca
//
LOCUS       DAOQPD010000142         4162 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_14048_length_4162_cov_18.959825, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000142 DAOQPD010000000
VERSION     DAOQPD010000142.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 4162)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4162)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4162
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_14048_length_4162_cov_18.959825"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..757)
                     /locus_tag="PK063_18235"
     CDS             complement(<1..757)
                     /locus_tag="PK063_18235"
                     /inference="COORDINATES: protein motif:HMM:NF019335.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor plug domain-containing
                     protein"
                     /protein_id="HMZ99045.1"
                     /translation="MNMCLFDPSKRVLVTVSLLMLCSGGPLWAAEPEVVESAEEIPVV
                     NASDVLISATRTPTSMGSVNQAVTIVSEEQLRQQLAASPSRSITQILTKLVPGMSQND
                     QSMDSGTSLKIRGRSIAILIDGVPQQSSPTTELDLAHIDPSAIERIEIIRGSTAIYGN
                     GAMGGLINIITKQPGEGKPSYYTDVQGSGSLTRVLRGLSGTVVQGFQGKKDWFDYNIV
                     GSFNHQGGMFDAEGSRTMPGTNTVGGFADTKNYN"
     gene            complement(973..1371)
                     /locus_tag="PK063_18240"
     CDS             complement(973..1371)
                     /locus_tag="PK063_18240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99046.1"
                     /translation="MIDLLRIMHSSRRSDWISRLLAVMACLLIGVRLVGGFVCNTCYL
                     DFEKPASRSFHLHGGGDREPCHHGQPEASPLIQWACTVMQDESAFVLPDIPRLPVVIS
                     LFVPLVLLLVSYRTLFPIAAHGRGPPAGRF"
     gene            complement(1480..1854)
                     /locus_tag="PK063_18245"
     CDS             complement(1480..1854)
                     /locus_tag="PK063_18245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biopolymer transporter ExbD"
                     /protein_id="HMZ99047.1"
                     /translation="MEREVDQINVIPLVDIMLVLLVIVLTTATFITTGQIPVNLAKAS
                     ASSDRQDRPIVVTVTAEGTVFVEDHAVTEEQLDTALAPHPRQSSVLVRADKVTRLERF
                     VAVVDRIRGLGFQQVSLEVFRA"
     gene            complement(1844..2269)
                     /gene="exbB"
                     /locus_tag="PK063_18250"
     CDS             complement(1844..2269)
                     /gene="exbB"
                     /locus_tag="PK063_18250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0015291 - secondary active transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-system energizer ExbB"
                     /protein_id="HMZ99048.1"
                     /translation="MESLKFGVEYGVIGLLGLLGVWALIIAIERWHFYRRVDPSAFVT
                     LDTFEMALTKRLVVIGTIAANAPYIGLLGTVLGIMLTFHTMGTSGAMAVSSIMVGLSL
                     ALKATAVGLLVAIPCVVMNNVLRRRVTELMTRYEARHGA"
     gene            complement(2495..>4162)
                     /locus_tag="PK063_18255"
     CDS             complement(2495..>4162)
                     /locus_tag="PK063_18255"
                     /inference="COORDINATES: protein motif:HMM:NF012546.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HMZ99049.1"
                     /translation="RFAATPEATDTVETRLMAVNRDGTEQTANLLKQGGFSSLFGQKH
                     VPQFEYQLVGMIPGDPRHVLLALDLEHPNAPDVYKVDVYSGERQLVQANPSSKPDRNA
                     ISHWIADRTGAVRSGVGQFQTAVHAIVRQPESTLWRELADYDLAKETGLVPLAFDADP
                     AWLYVRDQHRGKTAIFKLNVMDRAADRVLVVADPKFDLNGELVYAPGRKKVVGVRYSA
                     ADERVLFWDFDAQRLQARIDRAIPGTVNVIHSSSDDGRLHVVKSSGAAQPPRWSIFDE
                     QDGRMVLLGRSYPDLETAALAAPTTTYVTARDGKELQVFLTVPKDRDPRHLPMIVFPH
                     GGPAARMPGAFNYWTQWFVSRGWAVLEPRFRGTEGYGDDVLRAGFQRWGLEMQNDLTD
                     VVQYAVRAGIANAGRICIVGSGYGGYAALMGVVKTPDLYRCAVSLGGVTDLPQLVSDG
                     RGYLNQKPMVEARIGSWWNDRDRLRETSPVAHAQGMRTPLLLMHGSMDRSVPVSQSRN
                     LADALKAANATNARYVELPLADEALRREEDRLHVFSEMERFLTQHLD"
BASE COUNT          902 a         1308 c         1180 g          772 t
ORIGIN      
        1 tgttgtagtt cttggtgtcg gcaaatccac cgaccgtatt ggtgccgggc atggtacggg
       61 agccctctgc atcgaacatt ccgccctggt ggttgaagct gccgacgatg ttgtagtcga
      121 accagtcttt tttgccctga aagccctgca ccacggtccc actgagccct cgtaacacgc
      181 gggtaagcga tccactgccc tgcacatccg tgtagtagct tggtttaccc tcgcccggct
      241 gcttcgtaat gatattgatg agaccaccca tcgcgccgtt gccatagatc gcggtggagc
      301 cgcgaatgat ttcgatgcgt tcgatggcgc tgggatcgat atgagccagg tccaattccg
      361 tggtcgggct gctctgttgc gggacaccgt cgatcaaaat cgcaatcgac cggcctctga
      421 tcttcagcga cgtgccggaa tccatcgact ggtcgttctg cgacatgccc ggcaccagct
      481 tcgtcaaaat ctgcgtgata ctccggcttg gcgaggcggc cagctgctgc cgcaattgtt
      541 cttccgacac aatggttacg gcctgattca cgctacccat cgaggtcggc gtgcgagtgg
      601 ccgagatcag tacgtccgag gcattcacta ccggaatctc ttctgccgat tctacgactt
      661 ccggttcggc cgcccacaga ggccccccag agcacagcat caacaggctg actgtaacaa
      721 ggactcgttt tgagggatca aacaaacaca tgttcatggt gcacgacttc ctttccttca
      781 ccgacgcatc ggcctctacc caaggccgac gcagcacgga cgacaccgac gagccctgca
      841 gcgatagcga ccgtcggatc tgcttgagaa cgagaaccca ctcattcacg acagagccag
      901 ggcaccactg ggccacatcg gacaacacag gcgtccgact tgcggttgtt cattgatgtt
      961 gaagcgaaat gatcagaacc gaccggcagg agggccgcgt ccatgggccg cgatcggaaa
     1021 cagcgtacga taggacacga gcagcaggac tagcggcacg aacagcgaga tcacaaccgg
     1081 caggcgagga atgtcgggca agacaaaggc agactcatcc tgcatcacgg tgcaagccca
     1141 ctgaatcagt ggactggctt ccggctgccc gtgatgacag ggttcccggt cgccaccgcc
     1201 atgaaggtga aagctgcggc tcgcaggttt ctcgaagtcc agatagcagg tattgcagac
     1261 gaagccgccc acgagacgaa caccgatcaa caggcaggcc atcacggcga gcagacgtga
     1321 aatccagtcc gagcgtcgag aggaatgcat gatgcggagc aaatcgatca tgaaccaacc
     1381 ttcacacagg aaggcggcca ctctacgaaa gggcaggaaa aactgtctac agacgggtgc
     1441 tcacgggtgc tacagcgtgc cacacaatcg gtgtcgccct catgcccgga acacttccaa
     1501 acttacctgt tggaatccga gcccacggat ccggtcgacg acggcgacaa accgttctag
     1561 tcgcgtcacc ttgtcggctc ggaccagcac tgacgattga cgaggatgcg gcgccaaggc
     1621 ggtgtccagt tgttcctctg tgacggcgtg atcttccacg aagaccgttc cctccgccgt
     1681 aaccgtcacg acgatcggcc ggtcctgcct gtcgctcgac gccgaggctt tggcaagatt
     1741 gaccgggatc tgccccgtcg tgatgaaggt ggccgtggtt agcacgatca cgagcaggac
     1801 gagcatgata tcgaccagcg gaatgacatt gatctgatcg acctcacgct ccatgccgcg
     1861 cctcatagcg ggtcatgagt tcggtcaccc ggcggcgtaa cacgttgttc atcaccacgc
     1921 agggaatggc cacgagcaat cccaccgccg tggctttcag cgccagactg aggccgacca
     1981 tgatgctgct caccgccatg gcgccggagg tccccatcgt gtgaaacgtc agcatgatgc
     2041 ccagcaccgt ccccagcaaa ccgatatagg gtgcattcgc cgcaatggtg ccgatgacca
     2101 ccaatcgctt cgtcaacgcc atctcaaacg tgtccagcgt gacaaatgcc gacggatcga
     2161 cccgtctgta gaagtgccat cgctcgatcg cgatgattag cgcccacacg ccgagcagac
     2221 ccaagagacc gatcactcca tactccactc caaatttcag agactccatg gctttccgtc
     2281 ctcactgttc cttatcgatg acgtccatca cgcgcggccg ggaaaaggcc tgcgggcctc
     2341 acattggcgg cgctacgtta cgatggcctg cgcagaccgt ctactgacgc gtgctcatgg
     2401 ctgctacagt tcggagagac ccacggagag ggaaagttgg gataaagcta cgatgactag
     2461 acaggggaca atgtgtgcag gacagcagcc gggctcagtc gaggtgttgg gtaaggaacc
     2521 gttccatctc agagaatacg tggaggcggt cctcctcccg gcgcagggct tcatcagcga
     2581 gaggcaattc cacgtatcga gcgttcgtgg cattcgccgc tttgagcgca tcggccagat
     2641 tgcggctctg tgaaaccggc acggaacgat ccatggaccc gtgcatcaag agcagaggag
     2701 tgcgcatccc ttgcgcatga gccacgggcg atgtctcacg aagccggtca cggtcgttcc
     2761 accaggaacc gatccgtgcc tcgaccatcg gtttctgatt caggtacccc cggccatctg
     2821 acaccagttg cggcaaatcc gtcaccccgc ccagactgac cgcacaacga tagagatccg
     2881 gcgtcttcac gacgcccatc aacgcggcgt aacccccata gcccgaccca acgatgcaga
     2941 tgcgaccggc attggcgatg ccggcacgaa cagcatattg caccacatcg gtcaggtcgt
     3001 tctgcatctc cagaccccag cgttgaaatc cggcgcggag cacgtcatcc ccatagccct
     3061 cagtgccccg gaagcgcggc tccaacactg cccagccgcg gctgacgaac cactgtgtcc
     3121 aataattaaa cgcgcctggc atgcgtgcag caggtcctcc gtgaggaaac acgatcatcg
     3181 gaaggtggcg cgggtcccga tccttgggaa cggtcagaaa gacttgcagc tccttgccgt
     3241 cccgcgccgt cacataggtc gtggtgggag cagccagcgc ggccgtctcg agatcgggat
     3301 acgacctgcc gagcagcacc atccgtccgt cctgctcgtc gaagatcgac cagcgcggag
     3361 gctgcgctgc accgctcgac ttgacgacat ggagccgccc gtcgtcgctg ctgctgtgga
     3421 tgacattgac ggttccggga atcgcccggt cgatacgcgc ctgcaggcgt tgcgcgtcga
     3481 agtcccagaa gagcacccgt tcatccgccg cgctgtaccg cacgccgacg accttcttgc
     3541 gtccaggcgc atagaccagt tcgccattga gatcaaactt cggatcggcg accacgagca
     3601 cacgatctgc cgcacggtcc atcacgttga gcttaaaaat cgccgtcttg ccccgatgtt
     3661 gatccctcac atacaaccag gcgggatcgg catcgaaggc caggggaaca agtccggttt
     3721 ccttggccag gtcatagtca gccagttcgc gccagagtgt ggactccggt tgcctaacga
     3781 tggcatgcac cgcggtctgg aattggccca cccccgaccg cacggctcct gtgcggtcgg
     3841 caatccaatg ggaaatggcg ttgcggtccg gtttcgaact gggattcgcc tgaaccaact
     3901 gccgctcacc ggaatagaca tccaccttgt agacatccgg agcattggga tgttccagat
     3961 ccagcgcaag cagcacgtgc cgcggatcgc cgggaatcat cccgaccagc tgatattcga
     4021 actgaggaac atgtttctgt ccaaacaagg aggagaagcc accctgcttg agtaaattgg
     4081 cggtctgctc cgtgccatca cggttcaccg ccatcaatcg agtctcaacc gtgtctgtcg
     4141 cctccggggt agcggcgaac cg
//
LOCUS       DAOQPD010000143         4134 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_14175_length_4134_cov_21.840892, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000143 DAOQPD010000000
VERSION     DAOQPD010000143.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 4134)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4134)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4134
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_14175_length_4134_cov_21.840892"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(369..2228)
                     /gene="treZ"
                     /locus_tag="PK063_18260"
     CDS             complement(369..2228)
                     /gene="treZ"
                     /locus_tag="PK063_18260"
                     /inference="COORDINATES: protein motif:HMM:TIGR02402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malto-oligosyltrehalose trehalohydrolase"
                     /protein_id="HMZ99050.1"
                     /translation="MSSVRQRCGAHLSADGRMEWRVWAPYAKTVDLIVIDGAARRVEA
                     MTAEPHGYFFIRGGSASHGQQYAYSLDKGPDRADPASRWQPDGVTQPSAIVLPSRFQW
                     TDDRWEGVARDQLVFYEVHVGTFTAEGTFDAIIARLPSLRQLGVTALELMPVGEFPGT
                     RNWGYDGVYPFAPHHSYGGPEGLQRLVNACHEQGLACVLDVVYNHFGPEGSVQYEFGP
                     YFTDHYKTPWGRAVNFDGPGSEGVRAYVIENVRMWISDYHIDGLRLDAVHAIYDFGAT
                     HLLKEIKQAATEAAGDRKFPAYVVAESDLNDVRILLREDQGGYELDAQWSDDFHHTVH
                     ALLTGERQGYYSDYGTAEQLSAVLEKTFAIDGGFSRHRNRCHGAPAAGLPGDRFIGSI
                     QNHDQVGNRAGGERLSHLLPPPLQRLAAAFLLLAPHLPLLFMGEEYGEARPFQFFCSF
                     DGEELIESVRKGRRQEFEAFHTSDAQVTDPQDPSTFDQSRLTWRWDEVPHQAGLRRLY
                     TDLLEARRVWPAMRNYAERMSRLHRGADGAVVLELVRGGTKAAQAHTIQAFFNPTESV
                     QNLPARALPTLLFSSEWERYDGVRASSSESGQLLPFECAIFGPSDWKRYAGLE"
     assembly_gap    2641..2740
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <2741..3952
                     /gene="malQ"
                     /locus_tag="PK063_18265"
     CDS             <2741..3952
                     /gene="malQ"
                     /locus_tag="PK063_18265"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: protein motif:HMM:TIGR00217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HMZ99051.1"
                     /translation="RDRVYHLKQEALQLLWNSFEGDEDFDRFQSAGGRSLRQYALHCC
                     LVERYGSDWRRWPAVYRHPDSAEAEPALPAEVDRITFHMWQQWLLGRQLTDAGQIIPL
                     MQDLPIGFSPDGADAWTWQDVLAAEMTVGAPPDLFNATGQDWGLPPFIPHKLRATGYQ
                     PFIETIRSIICRAGGLRIDHVMGLFRLWWVPRGSPPKDGAFVRYAAEELLAILAVEST
                     RAQAIVVGEDLGTVEEGVRETLAEQNVLSYRLLWFEDQPPSQYPWKALASVTTHDLPT
                     LAGVWTGADLESQRKSGASPDEKAQEQFRTKLVEVSQVEDQTNLEEVITKTFSKLAES
                     PCAVVMADLEAACAVTERPNMPTSGGNYPNWSLALPCSLEELTAAERPAKLAHILNRR
                     VGDTIGTSSRP"
BASE COUNT          860 a         1241 c         1122 g          811 t
ORIGIN      
        1 gccacatgag ttgaaatagc cctgccacga gcgactggcg aggacatgaa cgtatccggc
       61 ctgagcgcta cgtacaagga gtgtcacgtg ggcctatcct aggagaagga cgcttcgttg
      121 ataactgggg cgaaccctgt agcactgtca gcaatgattg acagcctaaa ttttatgaaa
      181 gaacaggata tgggccgcct gcgcagggtg cgcgggactg ttctgcggct cagagacgct
      241 cgcattgagc aacgtcgagt ggtgtgcgaa tgcggcgaga tatacgtagg actgcctcga
      301 gctctgaatg actctcggca gggattcgta gatgtttagc tacctagtta gctgtcgccg
      361 cccagtcctc actcaagccc tgcgtaccgt ttccaatcag agggaccgaa gatggcacat
      421 tcgaacggga gcagctgacc gctctcagaa gatgacgctc gaacgccatc gtagcgttcc
      481 cattccgaac taaacaacaa ggttggtaat gcccgggccg gcagattctg aacgctctca
      541 gtaggattaa agaacgcttg gatggtgtgt gcttgcgctg ctttggtccc tccccgcacc
      601 aactccaaca ccactgcccc gtcagctcca cgatggagcc tgctcatgcg ctccgcgtaa
      661 tttcgcatgg ccggccagac tcggcgggct tccagtagat ccgtatagag ccgtctcaat
      721 cccgcttgat gggggacctc atcccaccgc cacgtaagac gggactggtc aaacgtagat
      781 gggtcctggg gatccgtcac ctgggcgtca ctcgtatgga aggcttcaaa ttcctggcgt
      841 cgccccttgc gcacagactc gatcagctcc tccccgtcga aggagcaaaa aaactgaaag
      901 ggtcgtgctt cgccgtactc ttcccccatg aacagcaacg ggaggtgtgg ggcgagtagc
      961 aagaacgctg cggcaagccg ctggagaggc ggtgggagca gatgactcag ccgctcgcca
     1021 cctgctcgat tacctacctg atcatggttt tgtatggacc cgatgaatcg atctccggga
     1081 aggcccgccg cgggcgcgcc gtgacatcgg tttcgatgac ggctaaaacc tccatcgatg
     1141 gcgaacgttt tctctagcac cgcactcaac tgttcggctg tgccatagtc cgagtaatag
     1201 ccctgccgct ctcccgtcaa cagcgcatgg accgtgtgat gaaagtcatc gctccattgc
     1261 gcatccagct cgtagccgcc ttgatcctcc cgtaaaagga tacgcacatc gttcagatca
     1321 ctttccgcga caacgtacgc cgggaatttt ctgtccccgg cagcctcggt agcggcttgt
     1381 ttgatttctt tgagaaggtg cgtcgcgccg aaatcgtaga tcgcgtgcac ggcatccagc
     1441 cttaatccat caatatggta atcgctgatc cacatgcgaa cattctcgat gacataggca
     1501 cgcaccccct cgcttccagg cccgtcaaaa ttcaccgcgc gtccccatgg cgtcttgtag
     1561 tgatcagtga aataggggcc gaactcatat tgaacgctgc cctcggggcc aaaatggtta
     1621 tagaccacgt ccagcacgca agccaggccc tgttcgtggc aggcgttgac gagccgttgg
     1681 aggccttcag gcccgccgta actgtggtga ggcgcgaacg gatagacccc gtcgtatccc
     1741 cagtttctgg tgcccgggaa ttcccccaca ggcatcagct ccagagcagt gacaccgagt
     1801 tgccgcaatg agggaaggcg ggcaatgatg gcatcaaacg ttccttcagc cgtgaaggtt
     1861 ccgacatgca cttcatagaa gacgagctgg tcccgcgcaa ctccttccca ccggtcatct
     1921 gtccactgaa agcgcgaagg caaaacgata gccgacggct gcgttacccc atccggttgc
     1981 cagcgtgatg cagggtccgc acggtcgggc cccttatcga gggaatacgc atattgctgc
     2041 ccgtgggacg cactgcctcc acggatgaaa aagtatccat gcggttcggc ggtcatcgct
     2101 tctacacgcc gagccgcgcc gtcaatcacg atgagatcga ccgtctttgc gtaaggagcc
     2161 cagacacgcc attccattct cccatcggcc gacagatgcg cgccgcatct ctgccttaca
     2221 ctgctcatcc catctcctcc acatcctatg ttcggaaact acctacatga atgaagaacg
     2281 ctacaggttg ggtagccctg tgcaaggcat gcgccacaca cggcgtctct ctcctccgct
     2341 gacggctctt gcctggtctc acatttagga gaatgagtgt ccgaacaacg gggacaagtt
     2401 gtctgtctag ggacaaaagg ccaccgcgat acgtcgcgat ctgatctttt ctctcataaa
     2461 atcccgtgga atcactcgcc cacaagccga gcctggacat tgcataacgc agcgccgtcc
     2521 tacaatcaac gacatcattg tccgcagacg tggcgttgca cctttacctc acggaggctt
     2581 taggccatgg cccaaggcct ggcaggaaga cagcgcaagg agaccgtgat tgagtgacgg
     2641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn cgcgatcgcg tctatcatct
     2761 caagcaagag gccttacaac tgttgtggaa tagctttgaa ggggacgaag atttcgaccg
     2821 ctttcagtcc gcaggggggc gctcgctgcg ccagtatgca cttcactgtt gtctggttga
     2881 acgttacggc tccgactggc gtcgctggcc tgccgtctat cgtcacccgg actcagccga
     2941 ggccgaaccg gccctgcccg cagaagtcga ccgcatcaca tttcatatgt ggcaacagtg
     3001 gctgctcggc cgacaactca ccgacgcggg gcagatcatc cccttgatgc aggatctacc
     3061 catcggattt tcaccggacg gcgccgacgc ctggacatgg caagacgtgc ttgcagccga
     3121 gatgacggtc ggagcgccgc ctgatctctt caatgcgacg ggccaggatt ggggacttcc
     3181 cccattcatt ccgcataaac tccgggcgac tggctaccaa ccgttcatcg agacgatccg
     3241 ctccatcatc tgccgtgccg gcggcttacg catcgatcac gtgatggggc tctttcgcct
     3301 gtggtgggtc cctcgaggca gtccgcccaa ggacggtgcc ttcgtgcggt atgcggcaga
     3361 ggagctgttg gcgatcctcg ccgtggaaag cactcgcgcg caggccatcg tcgtcggaga
     3421 agacctcggg acggtggagg aaggtgtgcg agagacactc gccgaacaga atgtcttgtc
     3481 ctatcgcctg ctttggttcg aagatcagcc cccgtcgcaa tacccctgga aagcgttggc
     3541 ctccgtcacc acccatgacc ttcccacctt agcaggcgtc tggacagggg cggacctcga
     3601 gtcacagcgc aaatccggcg cctcaccgga cgaaaaggcc caagagcagt tccggacaaa
     3661 gcttgtggag gtgagccagg tagaggatca gacgaatctc gaggaggtga tcaccaagac
     3721 gttctcgaaa cttgcggagt caccctgcgc ggtggtgatg gcggatcttg aagccgcctg
     3781 cgcagtgacc gaacgcccaa acatgcccac ttcgggcggc aactatccga actggtcgct
     3841 tgccctgccc tgttccctgg aggaactcac agcggctgaa cggcccgcga agctagcaca
     3901 catactgaac cggcgtgtcg gtgacacaat cggcacttct tctcgcccct aacctcttca
     3961 cgccatcgcg accacgatcc cacgccgcct gcgagacatc gttgcgtgta tggcctccat
     4021 caatagagca atcacccttc ctagctgaga gcggcgaccc gctctcagct aggcagaatt
     4081 tacagccagt tcacgcgctc ggccggccga atgtagatcg gctcttcgac ctga
//
LOCUS       DAOQPD010000144         4127 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_14215_length_4127_cov_18.782662, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000144 DAOQPD010000000
VERSION     DAOQPD010000144.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 4127)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4127)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4127
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_14215_length_4127_cov_18.782662"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(225..3656)
                     /locus_tag="PK063_18270"
     CDS             complement(225..3656)
                     /locus_tag="PK063_18270"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99052.1"
                     /translation="MAELYETAVTLLEEQPLPGRSRIIAHCVREIANALPALLAGVER
                     TRLEYDKRLDKIALARHRLTRLPIQAPRSMGGTSISDPQDALTQEFFNQIEELIKEHK
                     ATRLKRDTIAERLFQANRPENRHLGDALRPVLRRWTDLKDWFVGHAHDNGKTDAQCDW
                     SDIKRRFVLFERTVLTLGQGFFATIADLDELIRTSTPADVHLVVTQLGHIEHYKYFFE
                     HLDDPAWIPALRAEGIFNAPPSVEPNAIPRWAASEFLVRVIDRGDPTEGMKALSQIAD
                     ALTQQSLVNPLVIRDVVDVLRKVPAEHSVSFMPRLKQWAHHDRGFLFWRQLGKLVTHL
                     AEGGKPHEALTLLTPLLAIEGVRADDDFEYSYKPVKPRISMYEYIQIVDEHLRPVLER
                     RGEELFDVLCNILQKAAKLSRRSHSSEEWDDNSRVWQPDLSIQDEDDRDDVRSVLVVR
                     IRDAAETLLNDGRVDLGPLVEDLEARRWLIFRRLALYCLVTTASAPRDLIAPRLTHEA
                     SFRDRNLGKEYDSLLHIGFTRLTPDEQQTILSWVEAGPENIEQLIRNYETSTGRRATQ
                     EDIEKHHRSWQWKRLWPCHTALPATWRERYATLVEEFGEIEAPLPTTREARDVLEGER
                     APRPEQDLRTLTPAALREYLLAWTPERTTFPYPTRSGLAEVLTSLVTADPVAYANATE
                     EWLHLDPTFLHGIIRGFTKALQVDHPFSWAPVLSLCRWILAEPRTIPGRSVDRWEADL
                     DWGGTRWWIVELLRVGFQDETHGIPIDLRDVAWQLLETLTMDPDPEADEDEEDFGRPS
                     QSMNRAISSVRGRAIEALMFYPGWIKRQTGDAGPPRLPAEARAVLDRHLDLTEDPSLA
                     IRSLYGRWLPWILVFARDWGTASIPRIFPEYSQRYWLAAWEGFISFNNPYPEIFEPLQ
                     PVYAQAIAQLGSPSAEADDTRDQRDERLAGHLMTYYWRGHYPIEDETGLPYQFFARAS
                     DQVRAEAIEFIGRSLDRTDDPVESVVLDRLQRLWAQRFDGARQDPATHQAELRAFGWC
                     FGSGKFEPRWAVQNLLDVLRLTQSIDPDFQVLERLPDHAGAFPLEVLECAKRLIEGQT
                     SHVELSSWGEDLRRIFSQTRNHPAPEVRQASDDVIEVLGRFGHLGYADLLSRESG"
     gene            complement(3935..>4127)
                     /locus_tag="PK063_18275"
     CDS             complement(3935..>4127)
                     /locus_tag="PK063_18275"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99053.1"
                     /translation="QFRVQRSCGGMPDGWIEVLREGAAAPSFLLADRARSECARPMRA
                     VKADAATPKGNAGGKWREH"
BASE COUNT          951 a         1152 c         1050 g          974 t
ORIGIN      
        1 gcggcagtgg cctgggcccc ctctaacgct gatgcaggaa tgactgcgga aaagatgagg
       61 tagaacgcga gaagaagtgc catcacaaac cctcccacta tatttaattt atgggctaca
      121 gaggatgcct gtcaattaga gttcattgtt accgcagctt gatctcatta gaatattgcg
      181 aaattgatag gtcaccaagg acgattgcaa gggtccctct tcgtttagcc tgactcccga
      241 gaaaggagat ctgcatagcc gaggtgacca aatcttccaa gaacttcgat gacatcatcg
      301 gaggcctgcc ttacctcggg tgccgggtga ttcctggtct gggagaagat ccttcgaagg
      361 tcctcacccc aactggaaag ctcgacatga gacgtttgcc cttcaatcaa acgcttcgca
      421 cattcgagaa cctcgagtgg aaaagcaccg gcatggtcag gcaggcgctc cagaacctgg
      481 aaatctggat cgatactctg tgtcaaccgc aggacgtcca gaaggttttg gactgcccac
      541 cgtggctcaa attttcccga tccaaaacac cacccaaacg cacggagttc tgcctgatgc
      601 gttgctgggt cttgccttgc tccatcgaac ctctgagccc atagccgttg aaggcggtct
      661 aaaactaccg actccactgg atcatccgta cggtccaaac tcctacctat aaactcaatc
      721 gcctcggcgc gaacctgatc agacgcccga gcgaaaaatt ggtaaggaag gccggtctcg
      781 tcttcgatcg ggtagtgtcc acgccaatag tatgtcatga ggtgaccggc tagtctttca
      841 tctcgttggt cccgagtgtc atctgcctcg gccgatggac ttccaagctg cgcgatggcc
      901 tgcgcatata ccggctgaag cggttcaaat atttccgggt atggattatt aaaagatatg
      961 aagccctccc atgcggctag ccagtacctt tggctgtact cggggaatat ccgaggtatg
     1021 ctggcagttc cccaatcccg ggcgaacacc agaatccacg gaagccagcg gccatatagc
     1081 gagcgaatag ccagtgatgg atcttctgtc agatccaaat gcctatccaa cacagctcgc
     1141 gcttctgctg gaagtcttgg aggtccagcg tctcctgtct gccgttttat ccaccccgga
     1201 tagaacatga gggcttcgat agctcgaccg cgcaccgaac tgattgcgcg attcattgac
     1261 tggcttggcc ttccaaaatc ctcttcatcc tcgtccgctt ctggatctgg atccattgtt
     1321 aatgtctcca acagttgcca agccacatca cgaaggtcga tgggaatgcc atgcgtctca
     1381 tcctgaaaac cgacacgaag gagttcaaca atccaccaac gggttccccc ccaatccaaa
     1441 tcggcttccc agcgatcaac actccttcca ggaattgtgc gcggttcagc aaggatccac
     1501 cgacacagag ataagacagg cgcccaggaa aagggatgat ctacctgcag tgctttcgtg
     1561 aagccacgaa taatgccgtg aaggaacgtc gggtctagat gcagccattc ttccgttgca
     1621 ttggcatacg caacagggtc agctgtaacg agagaagtta aaacctccgc caatcctgag
     1681 cgcgtaggat aagggaaggt ggtccgctcc ggggtccaag cgagcaaata ctcccgtaac
     1741 gcggctggtg tgagtgttcg caagtcctgt tcgggtctgg gagcacgctc accttcaaga
     1801 acatctcttg cctctctcgt cgtcggtagc ggggcttcaa tttcaccgaa ttcctccaca
     1861 agagtggcat accgctcccg ccatgtcgcc gggagtgccg tgtggcacgg ccacagtcgc
     1921 ttccattgcc agctccggtg atgcttctcg atatcttcct gggtagcgcg ccggccggtg
     1981 ctcgtttcat agttcctgat cagttgctca atattctcag gtccagcttc aacccaactg
     2041 agaattgtct gttgttcatc aggagtcagg cgtgtgaaac cgatatgaag gagggagtca
     2101 tactcctttc caagatttct atctcggaac gaagcttcat gtgttagcct cggggcgatc
     2161 aagtctcttg gtgctgaagc tgtggtgaca agacagtata aggccaatcg tcggaagatc
     2221 agccaacgac gagcctcaag atcttcgacc aaaggaccga gatctacgcg tccatcattg
     2281 agtagcgttt cggccgcgtc tctaattctg actaccaaca cgcttctgac atcatcgcga
     2341 tcgtcttcat cctgaatact tagatctggc tgccagacac gggagttatc gtcccattct
     2401 tccgacgaat gtgaacggcg agacagtttc gctgctttct gcaggatatt gcataaaacg
     2461 tcaaacagct cctcccccct cctttctaat actgggcgaa gatgctcatc cacgatctga
     2521 atatattcat acatgctgat cctcggcttg accggcttgt atgaatattc aaaatcatca
     2581 tctgcccgca ccccttcgat agcgagcagc ggtgtcagaa gcgtcagtgc ttcgtgcggc
     2641 tttcctcctt ctgcaaggtg agttacgagt ttgcctagct gtcgccagaa caaaaagcct
     2701 ctgtcgtggt gagcccattg tttcagtctt ggcatgaaac ttaccgaatg ttccgcggga
     2761 accttccgca gtacatccac tacatcccga atcaccagcg gattcaccaa agactgttga
     2821 gtaagcgcat ccgcaatttg gctcaaagcc ttcatcccct cggtaggatc ccctctgtct
     2881 ataacacgca ctaggaactc tgaagccgcc caacgaggta tcgcattggg ctccacagac
     2941 ggaggtgcgt taaagatgcc ctcggctcgt agtgcgggaa tccatgccgg atcatccaag
     3001 tgctcaaaga agtatttgta atgctcaata tgtccgagtt gagttactac aagatggacg
     3061 tcagcagggg tcgacgtccg gatcagctca tccaggtcag cgatcgttgc gaagaacccc
     3121 tgaccaagtg tcagtactgt tctctcaaaa agaacaaatc ttcgcttgat atcactccaa
     3181 tcacattgag cgtctgtctt gccattatcg tgcgcgtgac cgacaaacca atccttaagg
     3241 tcggtccacc gcctcaaaac tggacgtagc gcatctccga gatgacgatt ctctgggcga
     3301 tttgcttgga aaagcctctc tgctatcgta tcgcgcttca gccttgttgc cttatgctcc
     3361 ttgatgagtt cttcaatttg attgaagaac tcttgagtca gagcgtcctg gggatcagaa
     3421 atcgatgtgc cccccatact cctcggagcc tgaatcggaa gcctggtcaa tctgtgccgt
     3481 gctagagcaa tcttgtccag gcgtttgtca tactcgagac gggtgcgctc taccccggcg
     3541 agaagagcgg gtaaggcatt ggcgatctct cggacgcaat gcgcgatgat acggcttcgt
     3601 cctggaaggg gttgctcctc gagaagagta acagcggttt catagagttc ggccaaagat
     3661 ggtgcttttt ccctcagcca atgacggagt cttcgtcgct gtgtagtcca tgtaggggtt
     3721 gatggcaaaa gcgggtgtgt ttcatctggc ggaggctggg ggacagcggc aggtccatta
     3781 ggcatagaca gggatgatta tatatatgcg acgaaatgat ttctcaagaa atcgtagcgc
     3841 cggaacggcc cccattaggc gcttggcggt cggctgaggt ggccctcaac tccgcgtcgt
     3901 ccaacgaggg ctttctgaag ccgcgcgtca agatctaatg ctccctccac ttaccccctg
     3961 cattcccctt gggagtagcc gcatcggcct tcactgcgcg catgggccga gcacattctg
     4021 atcgtgcgcg gtctgcgagc aagaaggacg gggcggctgc tccctctctc aacacttcga
     4081 tccatccgtc cggcatgcct ccgcacgatc gttgaaccct gaattgc
//
LOCUS       DAOQPD010000145         4050 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_14681_length_4050_cov_24.241552, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000145 DAOQPD010000000
VERSION     DAOQPD010000145.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 4050)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4050)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4050
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_14681_length_4050_cov_24.241552"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..626)
                     /locus_tag="PK063_18280"
     CDS             complement(<1..626)
                     /locus_tag="PK063_18280"
                     /inference="COORDINATES: protein motif:HMM:NF013161.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HMZ99054.1"
                     /translation="MNTFTAEVSRIQDLTHDVRAIELRLLEPASITFKAGQFVSFEVP
                     KEGHPRPVTRPYSIASPPEQRERILLVLNLVQGGPGSNYLFSLREGNRTSFKGPAGAF
                     YLRDDGTKDLCFVATGTGIAPVRSMILTQLQRQPDRPVTLFWGLRSQRDLYWQDEWAA
                     LAAIHPHLTVVTTLSRPEPGWQGASGRVTALVEERITSVRNLAVYLCGG"
     gene            complement(666..1379)
                     /locus_tag="PK063_18285"
     CDS             complement(666..1379)
                     /locus_tag="PK063_18285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HMZ99055.1"
                     /translation="MKILLLLLGGLKFGKIALTGGTMLLSMVAYSFFFGWWYAVGFVL
                     LILFHELGHYAAAKQRNLNVGAPTFIPFVGAWIQLKEQPMDVETEAYVGIAGPVAGTV
                     AAIACYYAAEYTQSQLLLALAYAGFMINLFNLIPLSPLDGGRITAIISPKVWWVGVPI
                     LIGLFIMNHSPMLLLIAIMAIPHVMSTFRGGPHGLPERYYDVPLSTRVNYGLYYLGLA
                     AFLGIMTYETHLLLPSGRG"
     gene            complement(1376..2275)
                     /locus_tag="PK063_18290"
     CDS             complement(1376..2275)
                     /locus_tag="PK063_18290"
                     /inference="COORDINATES: protein motif:HMM:NF021454.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2167 domain-containing protein"
                     /protein_id="HMZ99056.1"
                     /translation="MTWCHWRLMTAFLCWMVAGVALPALAEEPKPSGLHWLEGPTEAK
                     LGDQALLKLPKGYQFLGAQETQALLKRMGNFPSGSELGLITATGEGEQWFMVVRYIDA
                     GYVKDDDAANWDADALMTSIKEGTEEDNKNRQAQGFPPLIIRGWEEKPHYDKAANKVV
                     WAISAQEPESPVGVNYNTLALGRQGYLSMNMVGSLEQLPVLKPHVSQLLANVEFVEGK
                     RYTDFNSTTDKVAAVGLTALIAGAAVKSGLLAKLWAFIIPLLVAGKKLFMLLVIALGG
                     LAAKYLKKKPQAEQPGGGGGVSS"
     gene            complement(2455..2856)
                     /locus_tag="PK063_18295"
     CDS             complement(2455..2856)
                     /locus_tag="PK063_18295"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: protein motif:HMM:NF012478.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HMZ99057.1"
                     /translation="MKRSKALVLLDQREGEGPEAQRGDRVLYNCRLFLHCGDEVPLNE
                     RQAATLPGHMLRVDGGVTLVDHQVELGRRQVIPGIEQALLGMRAGGYRKVRISPHLAY
                     RDKGLPSLIPANALLVAEVWVRKIVKPEARE"
     gene            complement(2862..3974)
                     /locus_tag="PK063_18300"
     CDS             complement(2862..3974)
                     /locus_tag="PK063_18300"
                     /inference="COORDINATES: protein motif:HMM:NF022591.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2914 domain-containing protein"
                     /protein_id="HMZ99058.1"
                     /translation="MVSLQRFQSVLGKPYLPPLFFFSGVTYDTLVLTRIDRLRDNLLL
                     LAYLTLLGFLIVLTGRLGTQEATVDDLPPDAPFFMKWIVQAKPYAPMAIQFLLGGLFS
                     AYAIFYSKSATFAGTAVFFCVLVAFLVANEFLRSRLSNIQLLVSLYALVCFAFFTFFL
                     PVMTGWMNAVIFLAGAMVTVLIVLRVVQLIYWKNADRTTREAMWAGAPAVGLIALLVG
                     FYFMNWIPPVPLSLKFGGMYHEVKRSSDRYELSFEKSWYEVWKTSDNVIPADDPVYCF
                     TAVFAPVALKTTIYHHWYYRPDAGQPFADADRIPLKISGGREGGYRAYTFKEGLDPGD
                     WRVDVEAEDGRVIGRVAVKVLNKTTVGPLSLTTVVY"
BASE COUNT          903 a         1265 c         1115 g          767 t
ORIGIN      
        1 ccgccgcaaa ggtagaccgc gagattcctg accgaggtga tccgttcctc caccaacgcc
       61 gtgacgcgcc cactcgcccc ctgccacccc ggctccggtc tggacagtgt ggtaacgacg
      121 gtcaagtggg gatggatcgc ggccagcgca gcccattcat cctgccaata cagatcccgc
      181 tggcttcgaa gcccccagaa tagggtgacc ggccgatccg gctgccgctg caactgcgtc
      241 aggatcatgc ttcgcacggg cgcgatgccc gttcccgttg caacgaaaca caaatccttc
      301 gtcccgtcgt cccggaggta aaacgcgcca gccgggccct tgaatgacgt ccggttccct
      361 tcacgcaggc taaacaggta attcgaaccg ggcccgccct gaacgagatt caggacgagg
      421 aggattcgct ctcgctgttc cggcggtgac gcaatggaat agggcctggt caccgggcgg
      481 ggatgccctt ccttcggcac ctcgaacgag acgaattgcc cggctttaaa cgtgatactc
      541 gccggctcca gcaggcgcag ctcaatggcc cgcacgtcat gcgtcagatc ctgaatgcgg
      601 ctcacttcag ccgtgaaggt attcacagca gccagcctct gtacagatga tgccgaaaga
      661 tccggtcagc cacgcccgga gggaagcaag agatgcgtct catacgtcat gataccaaga
      721 aatgcggcga ggccgaggta gtacagacca tagttcaccc tggtcgagag cggcacgtcg
      781 tagtaacgct cgggcaagcc atggggaccg ccacggaacg tggacatcac atgcgggatc
      841 gccatgatcg cgatcaagag cagcatgggg ctatggttca tgatgaacag accgatcagg
      901 atcggcacac ccacccacca gactttgggt gagataatcg ccgtgatacg tccgccgtcc
      961 aagggggaca aggggatgag gttgaacaga ttgatcatga acccagcgta tgccagcgcc
     1021 agcagcaatt ggctttgggt atattcggct gcgtaatagc aggcaatcgc cgccacggta
     1081 ccggcaaccg gcccggcaat tcccacatag gcctcggttt ccacatccat cggctgctct
     1141 ttgagttgaa tccaggcacc gacgaaggga atgaaggtcg gggctcccac attcaggttg
     1201 cgctgtttgg cggccgcgta atgtcccaac tcgtgaaaca gaatcagcag cacgaatcca
     1261 accgcgtacc accagccgaa gaaaaaacta tacgccacca tcgacagcag catggttccg
     1321 ccggtcaggg cgatcttgcc aaatttgagg ccgccgagca gcagcaggag aatcttcacg
     1381 atgacacacc tccgcctccg cctggctgct ccgcctgcgg tttcttcttc aagtatttgg
     1441 cggccaaccc gccgagcgcg atgaccaaca gcatgaataa cttctttccc gccaccaaca
     1501 agggaatgat gaacgcccac agcttcgcca acaggccgga cttgacggct gcgcccgcga
     1561 tcagcgccgt caggccgacc gccgccacct tgtccgtcgt gctgttgaag tcggtatatc
     1621 gtttcccttc cacgaactcc acgttggcca gcagttggct gacatgcggt ttcagcaccg
     1681 ggagctgctc cagcgacccg accatgttca tgctgagata cccctgtcgt cccaacgcca
     1741 gcgtgttgta attgacccct accggcgatt ccggctcctg cgccgagatc gcccacacca
     1801 ccttgttcgc cgccttgtcg taatgcggct tctcttccca gccgcgaatg attaacggcg
     1861 gaaacccttg cgcctggcgg tttttgttgt cttcctccgt gccttctttg atggacgtca
     1921 tcagcgcgtc ggcatcccaa ttggccgcgt cgtcgtcttt gacgtagccc gcgtcgatat
     1981 atcgcacgac catgaaccac tgctcccctt caccggtcgc cgtgatcaac cccagttcgg
     2041 agccggaagg gaagtttccc attctcttca acaacgcttg ggtctcttgc gcaccaagga
     2101 attggtagcc tttgggaagc ttcagcaacg cctgatcgcc caacttcgct tcggtgggcc
     2161 cctcaagcca atgaaggcca gacggtttcg gctcctcggc taacgccgga agcgccacgc
     2221 cggcgaccat ccaacacaga aaggccgtca tcagacgcca atggcaccat gtcatggctt
     2281 cgtctccttc gaggatggag caacggaacg tgcttcaggc tgtaccatcg cttagatggc
     2341 gtcctgcttt cctgggactg cgattcatac aaacattcat catcctacct gaatacaccg
     2401 tagaagtggc tcccctttgg tcttaggatg gcattgcgaa tgatcttgcc tacgctattc
     2461 tctcgcttcg ggcttcacaa tcttccgtac ccacacctcc gcgaccagca aggcgttagc
     2521 gggaatgaga cttggcagcc ccttgtcccg ataagccagg tgcggactga tgcgaacttt
     2581 gcggtagccg cctgctctca ttccaagcaa cgcctgctcg attccaggaa tgacctgccg
     2641 ccgtcccagt tcgacctggt gatcgacgag cgttacgccg ccatcgactc tcagcatgtg
     2701 gcccggcaga gtcgccgcct gccgttcatt gagcggcacc tcatcgccgc aatgcaggaa
     2761 cagacgacag ttgtacagaa cacgatcccc ccgttgcgcc tccggacctt caccttcacg
     2821 ctggtcaagg agtacgaggg ccttcgaacg tttcatcgag actagtacac aaccgtcgtc
     2881 agagacagcg gcccgacggt cgtcttgttc agcaccttga ccgcgacccg gccgatgacg
     2941 cggccgtctt ccgcttccac atcgacccgc caatcccccg gatcgagtcc ctccttgaag
     3001 gtgtaggcgc gataccctcc ctcgcgcccc ccggaaatct tgagcggaat gcggtcggcg
     3061 tcggcgaagg gctgaccggc atcaggccgg taataccaat gatgataaat cgtcgtttta
     3121 agggcgaccg gggcaaacac cgccgtgaaa caatagaccg ggtcgtccgc cgggatgacg
     3181 ttgtccgagg ttttccacac ctcgtaccag gatttctcaa aactcagctc ataccggtcg
     3241 ctcgagcgct tcacttcgtg atacatgccg ccgaacttca gcgagagggg cacgggcgga
     3301 atccagttca taaaatagaa gccgaccagc agtgcaatca agccaacggc cggcgcaccg
     3361 gcccacatcg cttcccgcgt cgtacgatca gcgttcttcc aatagatcaa ctgcacaacg
     3421 cgcaacacga tcaggactgt caccatggct ccggcgagaa agatcaccgc attcatccag
     3481 ccggtcatga cgggcaggaa aaacgtgaag aaggcaaaac agacgagagc gtagagactg
     3541 accagcaact gtatgttcga tagtcggctc cgtaggaatt cgttcgccac gagaaacgcc
     3601 accaggacgc agaaaaagac ggccgtcccg gcgaaggtcg cgctcttgga ataaaagatg
     3661 gcgtaggcgc tgaagaggcc gcccagcagg aactggatgg ccatcggtgc atagggcttg
     3721 gcctgcacga tccatttcat gaagaagggc gcgtcgggtg gaagatcgtc caccgtggct
     3781 tcctgggttc ccaaacgccc ggtcagtacg atcagaaagc ctaacagcgt caggtaggcc
     3841 agcaagagca agttgtcgcg aagacggtca atcctggtga gcaccagggt gtcgtaagtt
     3901 acgccgctaa agaaaaacag cggcggcagg tacggcttac ccagaaccga ttggaaccgt
     3961 tgtaatgaga ccatgcgcta gatttcagga gacagaggcg attgtcaaac gaagagagga
     4021 atcaggcgat gaaattggaa ggcacgatcg
//
LOCUS       DAOQPD010000146         3990 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_15084_length_3990_cov_21.656163, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000146 DAOQPD010000000
VERSION     DAOQPD010000146.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 3990)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3990)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3990
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_15084_length_3990_cov_21.656163"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..435
                     /locus_tag="PK063_18305"
     CDS             <1..435
                     /locus_tag="PK063_18305"
                     /inference="COORDINATES: protein motif:HMM:NF014062.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HMZ99059.1"
                     /translation="MSWWLWAFLGILLLAGEMITPGGFYMLFFGIGALLVGALVGLDV
                     IQSAWMSWLLFSGLSVGSLLLLRPPLRRLMATDRGGISPVDTMAGETAIVLEDIPPDG
                     RGKAECRGSTWNAHNLGHKPLTKGQRSLVHHVDGITLWIKPE"
     gene            463..1401
                     /locus_tag="PK063_18310"
     CDS             463..1401
                     /locus_tag="PK063_18310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HMZ99060.1"
                     /translation="MPGGLWVVIFLAGLVLLVISKTARVVPQQSAYVVERLGRYSRTL
                     GAGFHILWPFLDSVQYKHSLKETAIDIPEQICITRDNVQVGVDGILYSKVLDPQRASY
                     GISDYRFAITQLAQTALRSEIGKIELDRTFEERTNINSQVVNELDKATEPWGVKVLRY
                     EIKNITPPKDVLAAMEKQMRAEREKRAVILTSEGERDAAINQAEGEKQQVIKASEAKK
                     QQQINEAEGAAAAIMAIAGATAEGLRKVAESTQVPGGYEAVQLRVAEQYITKFGELAK
                     TSNTLVLPANVSDVGSMLTLAMNMITKRSSPTPPGK"
     gene            1457..2035
                     /locus_tag="PK063_18315"
     CDS             1457..2035
                     /locus_tag="PK063_18315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-sedoheptulose 7-phosphate isomerase"
                     /protein_id="HMZ99061.1"
                     /translation="MKDFAIKAFDDSAEVKRRFARDHADKIVQVAQLIGRAFQTGHKV
                     LLFGNGGSATDAAHIAAEFVGRYKRERAPFPAIALATDIAAITCIANDYGFEELFARQ
                     VRAHGQAGDVAIAISTSGNSPNVLKGVEAAKAIGLTTVAWTGGSGGKLAGMVDYGFVV
                     PSTLTARIQESHITLGHVLCELIEDHVLANPA"
     gene            2019..3017
                     /locus_tag="PK063_18320"
     CDS             2019..3017
                     /locus_tag="PK063_18320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99062.1"
                     /translation="MPTRPKRTARSSTPPAIIKPIDASHLKTYPLQRRHSKVQVSNFA
                     KVWTGGRSFKRFLDSLPDILAVKTLREVAQAIAKAHRRGRPVIVGMGAHVVKVGLGPL
                     LVDLMERGIVTALAMNGAVIIHDFELAFMGHTSEEVDAEIDSGRFGMAEETGRMLNEA
                     ITLGMKDGLGLGESLGLYINRHKQQFPNRATSLLATGARLGLPVTVHVAVGTDIIHMH
                     PSADGAAIGAGSLLDFRRLAAVVSGMEGGVYLNLGSAVILPEVFLKAVSLGRNLGHSL
                     TNITTVNMDFLTHYRPMTNVVRRPTQKGGKGYALTGHHEIMVPLLAAAVIEELSGR"
     gene            3074..3685
                     /locus_tag="PK063_18325"
     CDS             3074..3685
                     /locus_tag="PK063_18325"
                     /inference="COORDINATES: protein motif:HMM:NF021759.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT-like domain-containing protein"
                     /protein_id="HMZ99063.1"
                     /translation="MAPSVEPLLTLWTNLNRRYFQGALPQIPIEWSRRLTSSAGMFVC
                     RVGPRHTHMQSTIDQTRRRCIKLSSVLLPAHNLDLDRETMTTLAHEMIHQWQYDVLKR
                     RPNHGQDFRRMMARMNQDGLGITIYHSLGKAVTALAKYAWRCQQCGSMYRRQRRTIQP
                     RRHLCGACRGPLRECAVVPDEPLAEPIPVGPVGRQFSLPFQSS"
     gene            3692..>3990
                     /locus_tag="PK063_18330"
     CDS             3692..>3990
                     /locus_tag="PK063_18330"
                     /inference="COORDINATES: protein motif:HMM:NF013015.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99064.1"
                     /translation="MSARWPRQILFGDIDAMFASAAVLADPSLAGKPVAVGGPPPRGI
                     IAAASYAVRRFGVRSAMPTIQALRLCPQLVLVPPDRPLYTRLHRQLQEVTDRFFP"
BASE COUNT          800 a         1268 c         1167 g          755 t
ORIGIN      
        1 atgagctggt ggctctgggc ctttctaggg atactgctgc tcgctggcga aatgatcacg
       61 cccggcgggt tttatatgtt gttcttcggc atcggggcgc tgttggtcgg cgcactggtc
      121 ggcttggacg tcatccaaag cgcatggatg tcctggcttc tgttctcagg cctttcagtc
      181 ggctccctgc tgctactacg cccgccactc cgccggctca tggcgaccga ccgaggcggg
      241 atctcgccgg tcgatacgat ggccggagaa acggccatcg tactggaaga tatccctccc
      301 gacggccgag gcaaagcgga atgccgcggc agcacatgga atgcgcataa cctcggccac
      361 aagccactca ccaaaggaca gcgcagcctc gtccatcacg tcgacggcat cactctgtgg
      421 atcaaacccg aatgaggtca tcccattatg gaggatagcg gcatgccagg cggactctgg
      481 gtcgtcatat tccttgcggg cctcgtgctc ctggtgattt ccaaaacggc gcgggtagtc
      541 ccgcaacaga gtgcctacgt ggttgaacgg ctcggccggt attcgcgcac gctcggggcg
      601 gggtttcaca tactgtggcc gtttctcgac agtgtgcaat acaaacactc gctgaaagaa
      661 accgccatcg atattcccga acagatctgt atcacccgcg acaacgtgca ggtcggcgtc
      721 gatggcattc tctattcgaa agtgctcgac ccgcaacgcg cttcttacgg tatcagcgac
      781 tatcgctttg ccatcactca gctcgcccag accgcgctcc gcagcgagat cgggaaaatc
      841 gaactcgacc ggacgtttga agaacgcacc aacatcaaca gtcaggtcgt caatgaactc
      901 gacaaggcca cggagccctg gggcgtgaag gtgttgcgct acgagatcaa gaatatcacc
      961 ccgccgaaag atgtcctggc tgccatggaa aagcagatgc gcgccgagcg ggagaaacgc
     1021 gcggtgattc tgacctccga aggcgaacgc gatgccgcca tcaatcaggc ggaaggcgag
     1081 aagcaacagg tcatcaaagc gtctgaagcc aagaagcagc agcagatcaa cgaggccgaa
     1141 ggtgcggccg ctgccattat ggccatcgcc ggcgccacgg ctgaggggct gcgcaaagtc
     1201 gccgagtcca cgcaagtccc cggaggctac gaagccgtgc aattgcgtgt cgctgaacag
     1261 tacatcacca agttcgggga actggccaaa accagcaaca cgctcgtact gccggccaat
     1321 gtctcggatg tcggctccat gctgacactg gccatgaaca tgatcaccaa acgatcgtcc
     1381 cccacgccgc ccggaaaata aacgccgtct cgtggtcgtt tgacagtggc ctggggcttc
     1441 cctacaattc cgcacgatga aagacttcgc cattaaggcg ttcgacgaca gcgcagaggt
     1501 caagcgacgc tttgcgcgag accatgccga caaaatcgtg caggtcgcgc aactcatcgg
     1561 ccgcgccttt caaaccggtc acaaagtgtt gctgttcggc aatgggggga gcgcgacgga
     1621 tgccgcgcac atcgccgcgg aattcgtcgg tcgttataaa cgggaacgcg ccccgttccc
     1681 ggccatcgcc ctcgccacgg acatcgcggc gattacctgc atcgccaacg actacggctt
     1741 cgaagaactc ttcgcccgtc aggtgcgcgc gcacgggcag gcgggcgatg tggctattgc
     1801 catcagcacc agcggcaact cccctaatgt gctgaaaggt gtcgaagcgg ctaaggccat
     1861 cggcctcacg accgtggcct ggaccggcgg ctcaggcggc aagttggccg ggatggtcga
     1921 ctacggcttt gtcgtccctt cgacgttgac agcccgcatt caggaaagtc acatcacgct
     1981 gggccatgtg ctctgcgaac tcattgagga tcacgttctt gccaacccgg cctaagcgca
     2041 ccgcgcgatc atcgacgccc cctgcgatca tcaagccgat tgatgcgtct cacttgaaga
     2101 cgtatccgct ccagcggcgg catagcaagg tgcaggtctc gaacttcgcc aaggtctgga
     2161 ccggcggccg ctcgttcaaa cgctttctcg attcgctgcc cgatatcctg gcggtcaaga
     2221 cgctgcggga ggtggcgcag gccatcgcga aggcacatcg tcgaggccgg ccggtgattg
     2281 tcggcatggg cgcgcacgtg gtgaaggtcg gactgggccc gctgctcgtg gatctgatgg
     2341 agcgcggcat agtgactgcg ctggcgatga acggcgccgt catcatccac gacttcgagc
     2401 tggccttcat ggggcacact tctgaggaag tcgacgcgga gatcgattcc ggtcgattcg
     2461 gcatggcgga agaaaccggc cgcatgctca acgaagccat cacgctaggc atgaaagatg
     2521 gcctgggcct cggggaatca ctgggcctct atatcaatcg tcacaagcaa cagttcccga
     2581 accgggccac cagcctcttg gcgaccggag ccagactggg cctccccgtc acggtgcacg
     2641 tggccgtcgg caccgacatc atccatatgc atccgtccgc cgacggcgcg gcgatcggcg
     2701 ccgggtcact gctcgacttc cgccgcttgg ccgccgtggt ctccgggatg gaaggcgggg
     2761 tctacttgaa cctgggatct gccgtcatcc tgccggaagt gtttctgaaa gccgtgtcgc
     2821 tcggacggaa tctcggccac tcgctgacaa acatcacgac cgtcaacatg gatttcctca
     2881 cccattatcg tcccatgacg aacgtcgtgc gccgcccgac tcagaaaggc gggaaaggct
     2941 acgccctcac cggtcatcac gaaatcatgg tgccgctgtt ggccgccgcc gtcatcgaag
     3001 aattgtccgg ccggtaaaat ccggaactcg tacgcgttca cctcgcacgg cctcgtatcg
     3061 ttctgtgatc aacatggcac cctctgtcga accgctcctc accctgtgga ccaacctcaa
     3121 ccgtcgatat tttcagggcg ccttaccgca gattcccatc gaatggagcc ggcggctgac
     3181 ttcctctgcg ggcatgttcg tgtgccgggt cggcccgaga catacgcaca tgcagagcac
     3241 catcgatcag acgcgacgcc gctgcatcaa gctgtcgtcg gtcctcctgc cagctcacaa
     3301 ccttgacctg gatcgcgaaa cgatgacgac gctggcgcat gaaatgatcc atcagtggca
     3361 atacgatgtg ctcaagcgtc gtccgaatca tggtcaggac tttcgccgca tgatggcgcg
     3421 catgaaccag gatggactcg gcatcacgat ctaccattcc ctgggcaaag cggtcacggc
     3481 actggccaaa tatgcctggc gctgccaaca atgcggctcg atgtaccggc gccagcgccg
     3541 gaccatccaa ccgcgacggc acctctgcgg cgcctgtcgg ggaccactcc gcgagtgtgc
     3601 ggttgtgcct gatgagccgc tggcagaacc aatccctgtg ggtcccgtcg gccggcaatt
     3661 cagtcttcca ttccaatcga gctagggttt catgtccgct cgttggcctc gacaaattct
     3721 attcggcgat atcgacgcca tgttcgcgtc agccgcggtg ctggccgatc catcattggc
     3781 gggcaaaccg gtcgccgtgg gaggtccgcc tccgcgcggt attattgcgg ccgccagtta
     3841 tgcggtccgt cgattcggtg tgcgatcggc catgcccacg atccaggccc tgcgcctctg
     3901 ccctcaactg gtcctggtcc cgcctgatcg tccgctctac acacgcctcc atcggcaact
     3961 ccaagaggtg acggaccggt tctttcctga
//
LOCUS       DAOQPD010000147         3963 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_15270_length_3963_cov_21.555015, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000147 DAOQPD010000000
VERSION     DAOQPD010000147.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 3963)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3963)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3963
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_15270_length_3963_cov_21.555015"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..329)
                     /locus_tag="PK063_18335"
     CDS             complement(<1..329)
                     /locus_tag="PK063_18335"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99065.1"
                     /translation="MAFCAVILMSACAQSVHQTQRLAQQDFMLDPGYAGAQNYSYWPG
                     PGYGYGIGYGAGYWGGPLGYYGGPYGPLGFGWYGGYGGFGAARPPSSMQGPRPSPPPH
                     APPQFRK"
     gene            complement(411..683)
                     /locus_tag="PK063_18340"
     CDS             complement(411..683)
                     /locus_tag="PK063_18340"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99066.1"
                     /translation="MIGSLLLTAGCAESWHQGQRHTVWSHQYNAGYGSAPVYGGAGYW
                     WNPFGYYGPGYGWYGGGSGGSHHSSSAPAPRPTPPDNAPPQFQKKY"
     gene            complement(722..1360)
                     /locus_tag="PK063_18345"
     CDS             complement(722..1360)
                     /locus_tag="PK063_18345"
                     /inference="COORDINATES: protein motif:HMM:NF024895.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein"
                     /protein_id="HMZ99067.1"
                     /translation="MAWIRYVRSRLSVVSLLAVLLLAPVASEAEWYAAAQLGVNFADP
                     IRNVRGSGSLAGLEAPNFNLKTSPAFGGKLGVFPNHGILGIELDVSHSTPHIKNLDDV
                     PGIHLSVTNIGPSVILRYPGMTWQPYIGVGPALLVAHLGRSTTTESDTQVSLGANVLA
                     GIRAFVTPKVAVFTEYKYTDSTFRFGGAFGPVGGFDGTYRAHQLFMGLSYHF"
     assembly_gap    1688..1787
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(2022..3227)
                     /locus_tag="PK063_18350"
     CDS             complement(2022..3227)
                     /locus_tag="PK063_18350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99068.1"
                     /translation="MTMPVQSPLSLAAFDLSPERGFLPATDPLDQLPEEPIINQIGTE
                     LPKFLTARQFRQFIQDRSDIMGPVADDWGLDVFRSAMRTLSFAGHAYVWEDPDHPAPS
                     LPASIAVPWYRIAQQLGRPPVLSYASYALHNWRRINPHQPIELGNIVLLQNFLGGLDE
                     EWFVLIHIDIEAKAGPGLQGLIDAQNAAQADDAESVLAGLRALAVAQEAMRETLLRMP
                     ERCDPYIYYSRVRPYIHGWKNSQALPQGLMYEGVTDYDERPQQFRGETGSQSSIVPAL
                     DAGLGVLHADDPLTQYLVEMRDYMPPRHRAFVAALEARTDGQQRPLLYGYARDRKMTH
                     PQLWKAFCTCVDLLAQFRDIHVGYAERYIFRQHQSHASNPTSVGTGGTPFMPYLNKHL
                     EETKQLIQD"
     gene            complement(3421..>3963)
                     /gene="pth"
                     /locus_tag="PK063_18355"
     CDS             complement(3421..>3963)
                     /gene="pth"
                     /locus_tag="PK063_18355"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: protein motif:HMM:NF013368.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HMZ99069.1"
                     /translation="EYAETRHNIGCWVIERAAARWSIRLTRKGAAQRGSGRAGSKLVE
                     LAQTLDWMNLSGPPLKGLLRELGLTPESLVVVHDDLDLDPGRLRIRQDGGSGGHNGLK
                     SIIEALGTSKFVRLKVGVGRPAPRQDSADYVLEPVSSEERALYAPCLDRAVDALELLL
                     NRDVATAMNQFNVREKLDDK"
BASE COUNT          856 a         1141 c         1114 g          752 t
ORIGIN      
        1 ttctttctga actgcggagg cgcgtgtggc ggtggcgaag gacgcggtcc ctgcatactc
       61 gatggcggac gcgccgcacc gaatcctcca tatccaccgt accagccaaa gcctaatgga
      121 ccgtacggtc caccatagta tcccagcggc ccgccccaat accccgcccc atatccgatg
      181 ccgtacccgt atccgggtcc aggccaatag gaataatttt gggcgcccgc atagccgggg
      241 tcgagcatga agtcttgctg ggccagtcgt tgcgtctggt gcactgactg ggcacaggcc
      301 gacatcaaga tcacggcaca gaatgccacg gcgcatgcgc ggaggcgtgt acgtactgct
      361 tcatgtgcaa ttaccattcg tctgtgcatg gcgacgatga tctctccgaa tcaatacttt
      421 ttctggaact ggggcggcgc gttatccggc ggagtcggcc gaggtgccgg cgcactcgat
      481 gagtgatggc tgccgccaga gccgccgcca taccatccat agccggggcc ataatatccg
      541 aatggattcc accagtatcc tgctccccca tagaccggtg cgctcccata cccggcattg
      601 tactggtggc tccatactgt gtgccgctgc ccctgatgcc aggactccgc gcagcccgcc
      661 gtcagcagga ggctaccaat catgcagctc cagataattg ctcgtatcat gccgcacctc
      721 gctagaagtg gtaagacagc cccatgaaca gttgatgggc gcgataggtc ccgtcgaatc
      781 cgcctaccgg cccgaacgct ccgccgaagc gaaacgtcga atcggtgtac ttatattcgg
      841 tgaacactgc gaccttcggt gtgacgaagg cacgaatacc ggccagcaca tttgcgccga
      901 gcgacacttg cgtgtcgctt tccgtcgttg tagatcggcc aagatgcgcc accaacaggg
      961 ctgggccaac gccaatatac ggctgccacg tcatgccggg ataccgcaga atgacgctcg
     1021 gtccgatatt ggtcacagag aggtgaatgc ccggcacatc gtcgagattc ttgatatgcg
     1081 gagtgctatg ggagacatct aactcaattc ccaggatccc atgattggga aacacgccca
     1141 gctttccgcc gaaggcggga ctggtcttca gattgaaatt aggcgcctcc aacccggcga
     1201 gagatccact tcctcgcacg ttccggatag gatcggcgaa attcaccccc agctgagcgg
     1261 ccgcatacca ttctgcctcg gatgcgacgg gagcaaggag gagtactgcc aacaacgata
     1321 cgactgaaag cctgctgcgc acataacgaa tccatgccat ggtgaagtgc tccatgggcg
     1381 aggcttacta acatcataac aggcgtccgg cgtagaagac tggacaactt tgctgttctg
     1441 acttccgcga tgtcgaatta cacgtgccct caatgggtcg ctgcgcgaga cggatcaatg
     1501 caggatagtt cgtggtcgat tcggtgacac tgcagtgcaa tcgaagaaga gcctcttaac
     1561 tgttacggct cattcctggc agaagaatta taaaggacgt acagcgcaat gccacccgcg
     1621 acagcaattg caatccccgc caacgcgcgg gtgccaaagc tcagcgggcc aagaaaaaat
     1681 tccgctgnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnatc cccgccaacg
     1801 cgcgggtgcc aaagctcagc gggccaagaa aaaattccgc tgcgcgaggc aatgccaccg
     1861 tggccagcag caccaaggcc agagcgatca ggtgtatccg aaggtaaatg ggttcgccgg
     1921 gtttacgcat agatcaacaa gtatcaacag ggcgcagtgt acgaactcca gccgcagtat
     1981 tccagtccga aacgaggcgc ggcgccatcg tccctgcgcg gttagtcctg gatgagttgc
     2041 ttggtctcct caagatgctt gttcagatag ggcataaatg gcgtcccacc tgtgcccacg
     2101 gaggtcggat tactcgcatg cgactggtgt tgacgaaaga tgtagcgctc ggcatacccg
     2161 acatgaatgt cacgaaactg ggccagcaag tccacgcagg tgcagaatgc cttccataat
     2221 tgcggatgcg tcatcttacg gtcgcgagca tacccgtaaa gcagtggccg ctgctgcccg
     2281 tctgtacgcg cctccagtgc agccacaaat gcgcggtggc gtggcggcat atagtcccgc
     2341 atctcgacca gatattgtgt caggggatca tcggcatgga gcacaccaag cccggcatcc
     2401 aacgctggca caatggaact ttgcgagccg gtttctccgc ggaattgctg cgggcgttca
     2461 tcatagtccg tgaccccttc gtacatcagc ccctgtggca gtgcctgact atttttccat
     2521 ccatggatat agggtcgtac gcggctgtaa taaatgtagg gatcgcaccg ttccggcata
     2581 cgaaggagtg tctcccgcat cgcctcctgc gcaacggcga gcgcacgtaa cccggccagc
     2641 accgattccg cgtcatccgc ctgcgcggca ttctgcgcat caatcagccc ctgcaatcca
     2701 ggtccggcct tcgcttcgat atcgatgtgg atcaagacaa accattcctc atcaagcccg
     2761 ccgaggaaat tctgaaggag cacaatgttt ccgagctcaa tcggttggtg tggattgatc
     2821 cggcgccagt tgtgcaacgc ataggaggcg tacgacagga ccggcggacg gcctaattgc
     2881 tgagcgatgc gataccacgg cacagcgatg ctggccggca aactgggagc tggatggtcc
     2941 gggtcctccc acacgtaggc atggccggca aacgacaggg ttcgcatggc cgaacggaag
     3001 acatcaagcc cccaatcgtc cgccacaggg cccatgatat ctgaccgatc ctgaataaac
     3061 tgacggaact gccgggcggt gaggaacttc ggtaactccg tcccgatctg gttgatgatt
     3121 ggctcttcag gaagctggtc caaggggtct gtggcaggaa gaaagccgcg ctcaggggag
     3181 aggtcgaacg cggcgagtga gagaggcgat tgaactggca tcgtcatgat tctcccaagg
     3241 taacgcgaat agttcactct accacaggga gagagatggc tgctgccgac ttgagaagcc
     3301 ctgccatgaa tgcgtcatcg taggaccacg ttcttcgaat gaacacgcca ccgaataaaa
     3361 gcgttggttt ttggggggga tgacgaacgg tccggacagg tgagagggat tgaacaatac
     3421 ttatttgtcg tccagctttt cccgcacgtt gaattgattc atcgccgtgg cgacatcgcg
     3481 attcaagagc aactccagcg catcgacggc gcggtcaaga cagggggcgt acagggctcg
     3541 ttcctcagat gagactggct ccagtacata gtctgcggag tcttgccgcg gagccgggcg
     3601 ccccactccg accttcaagc ggacgaactt agatgtgccc agagcttcga tgatcgactt
     3661 gagaccattg tggccaccgc tgccgccgtc ttgcctgatg cgcaatcgac ccgggtccag
     3721 atccaggtcg tcatgcacga cgaccaagga ctcgggcgtc agacccagtt cacgaaggag
     3781 acctttgagg gggggaccgc taagattcat ccagtcgagc gtttgggcca gctcgacgag
     3841 tttggaaccg gcgcgacccg agcctcgctg ggccgcgcct ttcctggtga gacgtatcga
     3901 ccatcgcgcc gccgcccgtt cgatcaccca gcagccgatg ttgtgccggg tctcggcata
     3961 ctc
//
LOCUS       DAOQPD010000148         3888 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_15809_length_3888_cov_19.288547, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000148 DAOQPD010000000
VERSION     DAOQPD010000148.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 3888)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3888)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3888
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_15809_length_3888_cov_19.288547"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..652)
                     /locus_tag="PK063_18360"
     CDS             complement(<1..652)
                     /locus_tag="PK063_18360"
                     /inference="COORDINATES: protein motif:HMM:NF012798.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HMZ99070.1"
                     /translation="MNTAVFRLLAQSEDYIRRCLEYAKIYLAIRRDQVAWIAPHLMVD
                     RNPMSGVKFFPEAIKTRFLTDDEIARLRHLMEPRVWEMVAFAIETGLRRSEQFNLRWS
                     QIDMENRVLSLPMPKGSKSRYVPLTDGVCGLLSRWDSFTKSPFVFPGKDPLKPLDARS
                     FVRWYFDPALRRAGIVGASWHSLRHTAATRRVLSGASLYGVQQLLGHRDIKTTARYS"
     gene            1204..>3888
                     /locus_tag="PK063_18365"
     CDS             1204..>3888
                     /locus_tag="PK063_18365"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ99071.1"
                     /translation="MHLPWGSLRLRAAKDYGLAVVITLSALLARFLLEPFIGDQLPYV
                     TFFAGVALSTFCTDLGPSLAAVILGGLAADYFFLEPRYSFVLVGQANYVGLTMYLLTT
                     LAIVGFGQTLRAFRRHAERITSGLQQEIVVRERVELALRESETRFRSVANTAPVMIWM
                     SDMTKRCIWFNKAWLEFTGRTMDDELGEGWMELVHAEDLAQCLQVYESAFDARETFTM
                     EYRLRRRDQEYRWLLDQGCPRLDPDGTFLGYIGSCVDITERRRAEAQLVESEERFRTL
                     ADNMSQFAWMADASGWLFWYNRRWYEYTGTTYEEMKGWGWQKVHHPDYLDHVMETWRK
                     AHATGEPWEDTFPLRGKDGMYRWFLSRAVPIRDNSGSITRWFGTNTDITELRNAHAAL
                     KQSEARYRALYDSIDEGFCIIEVMFDEHMGAVDFRFLETNPAFERQTGIQNARGQRMR
                     EIAPQHEMHWFDLFGTIALSGEPKRFEYPAVELHRWYEGYAYRVGEEYERKVGIIFND
                     ITVRKQAEEKLRQSEQRLRLALSAGQMGAWDIDLLTGSVTWDARQCDLFGMSKTDEPV
                     DMNKWYELVHPDDVGPLRAATARAETTGSFACEFRIVQPHSAERWIAGVGATLKNETG
                     QAVRMVGLNYDITERRKTEADLRTSAEELEHVVQARTQELVLSQERLRSLAAQLNLAE
                     QRERKRLAGELHDSLAQWLVLCQLYLGQVSRGSLTSDVGEKIRQTEDLLNQALNYSRT
                     LIAELSPRVLQDHGLVAGLTWLGEEMQRHGLAVRVVATKGVETTLSEDSSVLLFQSVR
                     ELLMNALKHARCNEVVVRLHRDEGNLCIEVQDDGVGFIATSNADETLSSKFGLFSIQE
                     RMTALGGMLNVQSRPGYGTIARLLLPLTSSATGLQPVKG"
BASE COUNT          893 a          977 c         1104 g          914 t
ORIGIN      
        1 ggctgtacct cgccgtcgtt ttgatatcgc ggtgtcctaa aagctgctgc acgccataga
       61 gactcgcacc cgataatacc cgccgggtgg cggccgtatg cctcagggaa tgccagcttg
      121 cgccaacgat tccggctcgc cgtagcgctg ggtcaaagta ccatctgaca aatgagcgcg
      181 cgtccagagg tttgagaggg tctttcccgg gaaatacgaa aggggacttc gtgaatgaat
      241 cccacctgga gagtagccca cataccccgt cggtcaatgg cacataacgg cttttcgaac
      301 ctttgggcat cggtaagctg aggactcgat tctccatgtc gatctgcgac catcggagat
      361 taaactgttc cgatcgccgc aaccctgttt caatcgcgaa tgcgaccatt tcccacactc
      421 gcggctccat caagtggcgg aggcgagcaa tttcgtcgtc tgtgagaaac cgggtcttga
      481 tggcctctgg aaagaatttc acgccgctca tcgggttgcg gtcaaccatc agatggggag
      541 caatccacgc tacctggtcc cgcctgatcg ctaaatagat cttggcatat tccagacaac
      601 ggcgaatgta gtcctcggac tgggctaaga ggcggaacac agcggtattc aaactcctac
      661 tctatcctga acatacgaag gaacggcttg tgtgagttct gccaattcga acgagcgtgg
      721 gtacggatct gttttcgaga caacaacgtg acgtgggaga tctggttcag ataccaggcc
      781 aatcgcccga catcagagag gtcctcaagc cctgctacga atcgagcatg ctctgaccga
      841 ctttagcctt ccggttcgcg cgataggtaa gtcgaagggc ttcgttctta acagtactct
      901 tcaacaaagc acaatgagac ttttttattg ctatagtttg gttttgagtt ggacctaaca
      961 atgtgttcca gtattactcc tctcggattc cttgccccca ttaactagga cctctgacag
     1021 ccaagctagg atcgccctgg cagggacgcc caataggctt ctatagcaac acgaacatcc
     1081 agtttcgcat ttcgatgctt gcacaagtga agactaggga ttaacctagg gtgatccctc
     1141 gttgttcacc gtacgaacgc caacctatcc gcgtgtacgt tcccttcaga agaggagagt
     1201 aggatgcatc tcccgtgggg ctcccttcga cttcgcgccg ccaaggacta cggcctggcg
     1261 gttgtcatta cccttagtgc tctgctggcc cgctttcttc tcgagccgtt cattggcgac
     1321 cagcttcctt atgtcacgtt tttcgctggt gtggctctgt ccacattttg caccgatcta
     1381 gggccgtcgt tggcggctgt cattctcggt ggattagcgg cggattattt ttttctggag
     1441 cctcgctact cattcgtatt ggtcgggcaa gccaattacg tcggattgac aatgtacctt
     1501 ctaaccacgc tcgccattgt cggttttggg caaaccctgc gcgcattcag gcggcatgcg
     1561 gaacgcatca ccagtggatt gcagcaagaa atcgttgtgc gagaacgggt ggaactagcc
     1621 ttgcgcgaaa gcgaaacacg ttttcgatca gtcgctaata ctgccccagt catgatctgg
     1681 atgtccgaca tgaccaaacg ctgtatttgg ttcaataaag cgtggctcga gttcaccggt
     1741 cgtacgatgg acgatgagct tggcgaggga tggatggagc tcgtccatgc tgaggatctc
     1801 gcccaatgtc tccaggtgta tgaaagcgca ttcgatgctc gcgagacgtt cactatggaa
     1861 tatcgcctcc gtcgccgtga ccaagaatac cgatggctgt tggaccaagg atgtccacgc
     1921 ctggatccag acggtacgtt tcttggttat atcggatcgt gtgtcgatat taccgagcgc
     1981 aggcgtgccg aagcgcagct ggtcgagagt gaggaacggt ttcgtacatt ggccgacaat
     2041 atgtcgcaat tcgcctggat ggctgatgcc agcggttggc tcttttggta caaccgccgc
     2101 tggtacgagt atacgggcac gacttacgag gagatgaagg gctggggttg gcagaaggtg
     2161 catcatccag actatctcga ccacgtgatg gagacatggc gaaaggctca tgccacaggc
     2221 gagccgtggg aagatacgtt tccattgcgc ggtaaagatg gcatgtatcg atggtttctc
     2281 tctcgagcag tacccattcg tgacaatagt ggctctatca ctcgttggtt tggaacaaac
     2341 acagatatta ctgagctgcg gaatgcccat gctgcgttga agcaatccga agcacgatat
     2401 cgcgctttgt atgactcgat tgatgaggga ttctgtatca ttgaggtgat gtttgatgaa
     2461 catatggggg cggtggattt tcgcttcttg gagacgaatc cggcgtttga acgacagacc
     2521 gggattcaga atgcacgggg tcaacgcatg cgggagattg ccccgcagca tgagatgcat
     2581 tggttcgact tgttcggcac cattgcgttg agcggagaac cgaagcggtt tgaatatcca
     2641 gctgtcgaat tacaccggtg gtatgaaggg tatgcctatc gggtgggcga agaatatgaa
     2701 cgaaaagtcg gcatcatctt caatgacata actgtacgga aacaggccga agaaaaactg
     2761 cgtcagagtg aacaacggct acgtctagcc ttatcggcag gccagatggg cgcctgggac
     2821 atcgaccttt tgacaggaag tgtcacctgg gacgcaagac agtgtgattt gttcggtatg
     2881 tccaaaaccg acgaaccggt ggatatgaac aagtggtacg agctcgtgca tccagacgac
     2941 gtaggaccgc ttagggccgc gactgcacgc gccgaaacca ctggttcgtt tgcatgcgaa
     3001 ttcaggatcg tgcagccaca tagcgcggag cgttggattg ccggcgtcgg tgcgacactc
     3061 aagaacgaga caggacaggc agtgcgtatg gtgggcttaa attacgatat cactgagcgt
     3121 cggaagaccg aagctgactt gcggacgtct gcggaagaat tggagcatgt agtccaggcg
     3181 cgcacgcagg aactcgtgct gtcacaagaa cgactacggt cactggcggc tcagctcaat
     3241 ttggccgagc aacgagaacg gaagcgtctc gccggcgagc tgcatgattc tctggcgcaa
     3301 tggctcgtgc tctgtcaact ctacctcggg caagtgagtc gtggatcttt gacgtctgat
     3361 gttggcgaaa aaatccggca gactgaggat ttgctgaacc aagcgctaaa ttacagccgg
     3421 acgttgatcg ctgaattgag tccacgagtt ttacaggatc atggcctcgt tgctggcctg
     3481 acctggctcg gcgaggaaat gcaacggcat ggtctagcgg tccgagtagt tgcgaccaaa
     3541 ggcgttgaga cgacactatc agaagattca agcgtgctac ttttccaatc tgtccgagag
     3601 ctactcatga atgcgctgaa gcatgcgagg tgcaatgaag tggtggttcg tctccatcga
     3661 gatgagggca atttatgcat cgaggtgcag gatgatggtg tcgggttcat cgccacttct
     3721 aatgcggacg aaactctttc gtcaaaattc ggacttttta gtatccaaga acgcatgacg
     3781 gcgcttggtg gaatgctcaa tgtccaatcc cggcctggtt acggtaccat agccaggctg
     3841 ttgctgccat tgaccagcag tgcgaccggc ctacagcccg tgaaggga
//
LOCUS       DAOQPD010000149         3885 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_15823_length_3885_cov_20.098695, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000149 DAOQPD010000000
VERSION     DAOQPD010000149.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 3885)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3885)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3885
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_15823_length_3885_cov_20.098695"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..905)
                     /locus_tag="PK063_18370"
     CDS             complement(<1..905)
                     /locus_tag="PK063_18370"
                     /inference="COORDINATES: protein motif:HMM:NF014542.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HMZ99072.1"
                     /translation="MTQTLPIPFYMLCGSLGAGKTTLLMRLLEYWNSQGHKVGVLMNE
                     AGEVSIDGPRAGTIADQVLNLAGGCICCDTKDDLAWSIAQLVQDYESTIIVLECSGMA
                     DPAEVVDAVTDAYVSRMVKLERIFAMLHPVPLPDTGMAELVTRNAIRYADDLILNKHD
                     LYIPGHWEQFRETVTRYNPYGRLWETNHARLDVAALLAAPQTRTTPTNVSFGKLPSAE
                     SRRDARSSHHPMVTTVRLPKPLNRTQFMEWTKSIPEGMERAKGFFRFEGEPELQEFQF
                     FPPRTSTIAPVMLLDEPDHVLVLIGR"
     gene            complement(1139..2080)
                     /locus_tag="PK063_18375"
     CDS             complement(1139..2080)
                     /locus_tag="PK063_18375"
                     /inference="COORDINATES: protein motif:HMM:TIGR01297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HMZ99073.1"
                     /translation="MLPHTYHELRSQLRIALAVNAVIVVAEFAGGFLTNSIGLIGDAG
                     HNLVDQGSLFLALYAHVLTARPATDSRTFGYHRAGIVAAFLNSFILLLTAGGITLVSI
                     ERLMAPVPVPGGWVMLIALISFAANLSIALLLQHGAKDDLNIRSAFWHMLSDAWVSLG
                     VVVSGGIIMVTGWSVLDPLVSLFVVLAIVRGAWPLFKESLEVLLESTPPGVSPALVAA
                     TIESIPGVKNVHDLHIWAVEPRLIMMTTHVQVDGGDQALTTDLLQTIRNRVTSEFKIK
                     HLTIQLETECCHPEAVHCDLSKLHDQHSHAEFLHTHH"
     gene            complement(2204..>3885)
                     /gene="ftsH"
                     /locus_tag="PK063_18380"
     CDS             complement(2204..>3885)
                     /gene="ftsH"
                     /locus_tag="PK063_18380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HMZ99074.1"
                     /translation="PYSEFKSAVDANKVTEVTVSPQIIHGKMKEDKVFHTIRIEDPDL
                     LRNLAQHQVKVTGMIESTLFRDLLSWILPIVLFFGVWWFLLRRMGQSQGFMTVGQSKA
                     KIYVENEVKVTFADVAGVDEAKQELEEIIEFLKTPEKFRRLGGKIPKGILLVGPPGTG
                     KTLLAKAVAGEAGVPFFSISGSEFVEMFVGVGAARVRDLFEQAKGKAPCIIFLDELDA
                     LGKARGVGPMAHEEREQTLNQLLVEMDGFDSRVGVILVAATNRPEILDPALLRAGRFD
                     RQVLVDRPDKIGRLAILKVHARSITLANQADLETIAAMTPGFVGADLANLLNEAALLA
                     VRRGKDTVSLSELQEAVERVIGGLEKKNRVLNKMERARVAHHEVGHALMALSIPGGDA
                     VHKISIIPRGIAALGYTMQLPTEDRFLMTVSELKNRIAILLGGRAAEEVIYGEVSTGA
                     QDDLRKATDIAKSMIKSYGMSEKLGQVSLERDRQSVFLQTGPSQTPGDYSEHTSREID
                     CEVRLLIDEQYERARDLIKAQEATLRHAAHVLLEKETITGEELKALAAPPQ"
BASE COUNT          740 a         1072 c         1254 g          819 t
ORIGIN      
        1 cgtccgatca acaccaggac atggtccggt tcatcgagca gcatgaccgg agcaatggtg
       61 ctggtgcgag ggggaaagaa ctgaaactcc tgtagctccg gttctccttc aaaccgaaaa
      121 aatcccttcg cgcgttccat tccctccggt atcgacttcg tccattccat gaactgtgtc
      181 cggttcagcg gtttcggtaa ccgtacggtg gtcaccatcg ggtgatgtga tgatcgggcg
      241 tcgcgcctgc tctctgccga gggcaatttc ccaaacgata cgttcgttgg agtggtccgt
      301 gtctggggcg cggcgaggag ggcggctacg tcgagcctgg cgtgattggt ttcccacagg
      361 cgaccgtagg gattgtagcg ggtgacggtc tcgcgaaact gttcccaatg gccggggatg
      421 tagaggtcgt gtttgttcag gatcaaatca tctgcatacc ggatggcatt ccgcgtgacg
      481 agctcggcca tgccggtatc gggcagggga acggggtgca gcatggcaaa aatccgttcg
      541 agtttcacca tacgggagac ataggcgtcc gtcaccgcat ctaccacttc tgccggatcg
      601 gccatgccgg aacattccag aacaatgatg gtggactcat agtcctgcac cagctgagcg
      661 atgctccagg cgagatcgtc tttcgtatcg caacagatgc agccgccggc caggttcagg
      721 acctggtctg cgatggtgcc cgctcgtggg ccgtcgatgc tgacctctcc tgcctcgttc
      781 atgagcacgc cgactttgtg cccctggctg ttccaatatt cgagcagtcg catgagcagg
      841 gtggtcttgc cggcgccgag tgagccgcac agcatataga aggggatggg cagtgtctgt
      901 gtcatgcggc ccattgtagc cgctgaggtc ctgtggcggc taggtggcgc tttcatgcgc
      961 agctttggca caaagatatc tcgcgatcac aggcagatgg ttgggcaggt ttcccggcgg
     1021 atggtcaaaa agtccgccag cgcggccgca gcgagcgagg aggcgaggcg tacccttgcg
     1081 gtacgttgag cttttgagcg atgcgagaac aatgctggcg gattttttca ccatccgcct
     1141 agtgatgcgt gtgcagaaat tccgcgtgcg aatgctggtc gtggagtttg gagaggtcgc
     1201 aatggacggc ttcggggtgg cagcattcgg tttcgagttg aatggtcaga tgtttgattt
     1261 tgaattcact ggtgacccgg ttgcggattg tttggaggag gtcggtcgtt aaggcctgat
     1321 cgccgccgtc gacctgtaca tgggtggtca tcatgatgag gcgtggctcg accgcccaga
     1381 tatgcaggtc gtggacgttc tttaccccgg ggatggattc aatggttgct gcgaccagcg
     1441 ccgggcttac gccgggcggg gtggactcca gtaagacctc aagcgattct ttaaagagcg
     1501 gccaggctcc cctgactatg gccagcacca cgaacagact caccaggggg tcgagcacgg
     1561 accagccggt gaccatgata atgccgccgc tcacgacgac gccgagcgac acccaggcat
     1621 cgctcagcat gtgccagaag gcgctgcgga tattgaggtc atctttcgcg ccgtgttgga
     1681 gcaagagcgc gatggaaagg ttcgcggcaa agctgatcaa ggcgatcagc atgacccatc
     1741 ctcccggaac ggggacggga gccatgaggc gttcgatact gacaagggtg atgccgccgg
     1801 cggtgaggag caggatgaag gaattgagga acgccgcgac gattcctgcc cggtgatagc
     1861 cgaaggtgcg gctgtcggtg gcgggacggg ccgtcagcac atgggcatag agcgcgagga
     1921 agagagagcc ttgatcgacg aggttatgcc ccgcgtctcc gatcaggccg atgctgttcg
     1981 tgagaaagcc gccggcaaac tccgcgacga cgatgacagc attgacggcc agggcgatgc
     2041 ggagttgcga gcggagttca tggtaggtgt ggggaagcat cgacttcagt gtctcacgag
     2101 aggcggagga gggcaagccg ttgtgtggtc ttcaagtgac tgcggaccag tgcgcgagat
     2161 ctcttggatt ctcaagggag agaggcgagg caaggaggcg gcgttactgg gggggtgccg
     2221 cgagggcttt gagttcctcg ccggtaattg tttctttctc aagcaagacg tgagcagcat
     2281 gccgcagcgt ggcttcctgg gctttgatga gatcgcgtgc ccgttcgtat tgctcgtcga
     2341 tcaagagtcg aacttcgcaa tcgatttctc tcgacgtgtg ctcactgtaa tcgccgggcg
     2401 tttgagacgg accggtttgc aaaaagacgg attgccggtc ccgctccagg ctgacctgcc
     2461 caagtttttc gctcatgccg tatgacttga tcatgctctt ggcgatatcg gtggccttgc
     2521 gcagatcgtc ctgagcgccg gtggagacct cgccgtagat gacttcctcc gcggcgcgtc
     2581 cgcccagcag aatggcaatg cggttcttga gctcggacac cgtcatgaga aagcggtctt
     2641 cggtcgggag ctgcatggtg tagccgagcg cggcaatacc tcgagggata atggagattt
     2701 tgtggaccgc atcgccgccc gggatagaca gggccatcag cgcatggccg acctcatgat
     2761 gcgccacgcg ggcgcgctcc attttgttca gcacccgatt cttcttttcc agcccgccga
     2821 tgacgcgctc gaccgcttcc tgtaattcgg acagactcac cgtgtccttg ccgcgccgta
     2881 cggccagcaa ggctgcttcg ttcaggagat tggccaggtc ggcgccgacg aagccgggcg
     2941 tcatagcggc gatagtttcg aggtcggcct gattggcgag ggtaatgctg cgcgcgtgga
     3001 ctttcagaat cgcgaggcgg ccgatcttgt cgggccggtc caccagcacc tggcgatcga
     3061 agcggcctgc gcgaagcagt gcggggtcca aaatctcagg acggttggta gcggccacga
     3121 ggatgacgcc gacgcgggag tcgaagccat ccatttcgac cagcagctgg ttgagcgtct
     3181 gttcccgttc ctcatgggcc atcggtccga ccccgcgcgc tttccccagc gcgtcgagct
     3241 catcgaggaa gatgatgcag ggcgctttgc ccttggcctg ttcgaacagg tcgcggacac
     3301 gagcggcgcc gaccccgacg aacatctcca cgaattcaga cccgctgatc gaaaaaaacg
     3361 gcacaccggc ttctccggcc acggccttcg cgagtagcgt cttgcctgtg cccggggggc
     3421 cgacgagcag aatgcccttg ggaattttcc cgccgaggcg ccggaatttt tccggcgtct
     3481 tgagaaattc gatgatctct tcgagttcct gctttgcctc atcgacgccc gccacatcgg
     3541 cgaaggtgac cttcacttcg ttctcgacat aaattttggc tttgctttgc ccgaccgtca
     3601 tgaagccctg gctctgaccc atgcggcgga gcagaaacca ccagaccccg aagaacagca
     3661 cgatcggaag aatccacgac aagagatccc ggaacagagt gctctcgatc atgcccgtga
     3721 ccttgacctg gtgttgggcc aggtttcgca gcaggtccgg gtcttcgatg cgaatggtat
     3781 ggaagacttt gtcttccttc atcttgccgt gaatgatttg cggcgagacg gtcacctcgg
     3841 tgaccttgtt cgcgtccacg gcggatttga attcgctgta cggga
//
LOCUS       DAOQPD010000150         3859 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_15980_length_3859_cov_19.097529, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000150 DAOQPD010000000
VERSION     DAOQPD010000150.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 3859)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3859)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3859
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_15980_length_3859_cov_19.097529"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..634)
                     /locus_tag="PK063_18385"
     CDS             complement(<1..634)
                     /locus_tag="PK063_18385"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99075.1"
                     /translation="MNTLVSSVLGRTDSDVLAWDTYVLNSPITSGYHLAGWRRVIEEA
                     FGHRTYYLIARDEHGAVQGIVPLVLLASRVFGRFLVSLPFVNYGGLVATSPDAYRVLE
                     GGAIEQANALDAAHIELRHERPIETGWVSTERKVSMRLSLPGSYESLVKAFPSKLRSQ
                     VRRAQKEGMTARIGGNECLDEFYAVFSRCMRDLGTPVYAKGFFAKILEVFP"
     gene            complement(642..2015)
                     /locus_tag="PK063_18390"
     CDS             complement(642..2015)
                     /locus_tag="PK063_18390"
                     /inference="COORDINATES: protein motif:HMM:NF024968.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HMZ99076.1"
                     /translation="MKRVLMVAYYFPPVAASGAMRPLGFCRNLAAYGWQPQVLTTTPE
                     CVYPSHQVDLKLGERVPADVEVIRVPYIDRLQRVLQYREMLKGMVRRGPAHKSASNPG
                     AAVRPPDSSPGRSTLKDFILDWAFAFPDRQCGWLSRAVRKLQTLHEKDVPHVIFATGG
                     PWTNFLIGDTLAKHFHCPLVLDYRDPWNCNPYYSFNSDALTRKSRATEAQVCQGASHV
                     IANTDELRERLIEEYEFLRDRCTWIPNGFDRETLSPPHVPQERSGLGLTSSGYELCHF
                     GTVYGKRTPRILLQAVWELFQENQLKPEAIRLRFVGGWDTTDQECEYYAANLEKYGFL
                     RREPPVSHSVCLREMQRSSVLLVLQPDSPLQVPAKIYEYVATGRPLLLIGGEGATANL
                     VARHGLGVSSPNHIARIKALLKDLTTGTQRLVPPDAARVNRFEYRSLTGELAAILDAA
                     VRPRPVG"
     gene            complement(2151..>3859)
                     /gene="asnB"
                     /locus_tag="PK063_18395"
     CDS             complement(2151..>3859)
                     /gene="asnB"
                     /locus_tag="PK063_18395"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: protein motif:HMM:TIGR01536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HMZ99077.1"
                     /translation="QPMVSQDGQYVLVFNGEIFNYVELRDELRKLGHQFRSSGDSEVL
                     LAAYREWGRECLPKLNGMWAFVIYDRRHRRLFGSRDRFGVKPLYYSRDHTVIQFASEI
                     KALRASGYQRVGINWRIASRFLLEGRLDSHNETFYDGIEQIPPGSGFEVGLDGAWHQW
                     TFWTLDALPKTIAPDPAATFGDLFEDSVRIRMRSDVPVGVCLSGGLDSTAIICAAARH
                     RDESAGTQPESLQAFCYMAKEFDESKYIADTLLQTHAQLRQLETSPAELWNDVRKVLW
                     FQDEPVHTMTAVVGYQLMRLAASQGIRVVLNGQGADETIGGYSSYFQDYWVSLLQQGR
                     VGAAWQAVKAYTEAHGGNSRARMTAAASRCISWEMYKIGSYRTWAQARRQARIRQNPW
                     FSGDLTKHFISEDTPPSSAALSTALKQSVISAPLPLYLRIEDRNSMAHSVEARLPFLD
                     YRLVSFVCGLSDEWKVRGPWNKYVLREGMKGRIPESVRSRVDKMGFPTASKKWFAHDL
                     YEPLREILASRTLRERGIYNTGALIADLDRHRRGEADFSNRLFHVAEFEILSDLAGQS
                     PA"
BASE COUNT          933 a         1115 c          954 g          857 t
ORIGIN      
        1 tcgggaacac ctcaagaatc tttgcaaaaa accctttggc atagacggga gttcccaaat
       61 cgcgcataca tcgggagaac acggcataaa attcatccag gcactcgttc ccgcctatgc
      121 gtgctgtcat cccttctttc tgagctcggc gaacctgact gcgtaacttt gaagggaacg
      181 cttttaccag cgactcgtat gacccaggca atgacagcct catcgaaact tttcgttcgg
      241 tggaaaccca gccagtctct atcggccgtt catgtcgaag ttcgatatgc gctgcatcca
      301 gcgcgttcgc ctgttcaatg gcaccgcctt ccagcactcg atacgcatcg ggagaggtag
      361 cgacaaggcc tccgtagttt acgaacggca gagaaaccag aaaccgacca aatacccggc
      421 tggccaacag caccaacggc acgatgccct gcacagctcc gtgttcgtcc cgagcgatca
      481 gataataggt acggtggcca aaggcctcct ctatgacacg gcgccagcct gccagatggt
      541 atccggatgt aatgggagag ttcagaacgt acgtatccca tgccagaaca tccgagtcgg
      601 ttcgcccgag aactgatgag accaacgtat tcatacagcg attaccctac cggtctggga
      661 cgaacggcgg catcgagaat agccgctaat tctccggtca gcgatcgata ttcaaaccga
      721 tttacccgag cggcatcggg cggaacgagt ctttgcgttc ccgttgtgag gtctttcaat
      781 aacgccttga tgcgtgcaat gtgattcggg ctgcttacgc ctaatccatg ccgagccacc
      841 aaattggcag ttgcgccttc cccgccaata agcaacagcg gccgaccggt cgcaacatat
      901 tcgtatatct ttgcgggcac ctgcaaagga gagtctggct gcaggacaag taagacgctt
      961 gatcgttgca tttctctgag gcacacgcta tgcgaaaccg gaggttcgcg ccggagaaat
     1021 ccatatttct ctagattggc ggcataatac tcacactctt ggtctgttgt gtcccagccc
     1081 ccgacgaaac gcaatcgaat ggcttccggc tttaactggt tctcctgaaa caactcccac
     1141 acggcctgca acaaaatccg cggggttctt tttccataca cggttccgaa atggcacaac
     1201 tcatatcctg aagacgtgag ccccaggccc gatcgctcct gaggcacgtg tgggggtgac
     1261 agcgtctctc gatcgaatcc attggggatc cacgtgcagc ggtctcggag aaattcgtat
     1321 tcttcaataa gtcgttcgcg aagctcgtcc gtattggcga tcacatgact tgcaccctga
     1381 cagacttggg cttcagttgc tcgtgatttc ctggtcaacg catccgagtt gaaggagtaa
     1441 taaggattac aattccaggg gtcccgataa tccaacacca gcggacaatg aaagtgcttg
     1501 gcgagcgtgt cgccgatcaa aaaatttgtc catggcccgc cggtcgcaaa aatcacatgc
     1561 ggaacatcct tctcgtgaag agtctgtagt ttccgcacag ctcggctcag ccacccgcat
     1621 tgacgatctg gaaatgcgaa cgcccaatcc agaataaagt ctttcagcgt cgaccggcct
     1681 ggactcgaat caggtggtct caccgcagca ccggggttgc tcgcggattt gtgagcaggc
     1741 cctcttcgta ccatcccctt cagcatctca cggtactgca agacccgctg aaggcgatct
     1801 atatacggca ctcgaatgac ctcaacatca gcaggaactc gctcgcctag cttaagatca
     1861 acctgatgcg acggatatac acactccgga gtggtcgtga gcacctgagg ttgccagcca
     1921 taggccgcca ggtttcgaca aaatccaagc ggtcgcatgg ccccactcgc cgcaacgggg
     1981 ggaaagtaat aggccaccat gagtactcgt ttcaccgtct caccgccagc tttatgcaaa
     2041 atcatgattg tcggagatta gtccggtaat ctgatgaaat gaatgtcgtc acagaacaac
     2101 tgaccgggaa tacgccctca ggtgctgcgc acttcaaacc gttctagaat ctaggctggc
     2161 gactgccctg caagatctga caatatttca aattcggcga catggaagag tctattcgaa
     2221 aaatctgctt ctcctcggcg atgccgatcc aagtcagcta tgagagcacc cgtgttatag
     2281 attcctcgct ctcgcaaggt gcgactcgcc aggatttctc gaagcggctc atacaagtca
     2341 tgcgcgaacc actttttact cgcggtagga aatcccatct tgtccactct gctccgcaca
     2401 gactcaggga ttctgccctt catcccctct cgcagcacat atttgttcca cggacctcgt
     2461 accttccatt cgtcagatag accgcacaca aacgacacga ggcgatagtc caagaacggg
     2521 agtcgcgcct ccacagaatg agccatggag tttcgatctt cgatccgaag atataagggt
     2581 aacggagccg atatcaccga ctgttttaat gctgtggaca aagcggcgga actgggcggg
     2641 gtatcttcgc tgataaaatg tttcgttaaa tcaccagaga accatggatt ttgacgaata
     2701 cgggcttgcc ttctggcctg agcccatgtg cggtagctgc caatcttgta catctcccag
     2761 gaaatgcagc gacttgccgc cgctgtcata cgcgcacgcg aatttcctcc atgtgcctcg
     2821 gtataggctt tcaccgcctg ccaggcagca ccgacacgcc cttgttgcag gagagacacc
     2881 caatagtctt ggaaatagct tgaatacccc ccaatcgttt catcggcgcc ctgtccattc
     2941 aggacaacgc gaatgccttg ggaggcggcc agacgcatga gttgatagcc gaccacggcc
     3001 gtcatggtat gcacaggctc gtcctgaaac cagaggactt tgcgcacatc attccagagt
     3061 tcggcggggc ttgtttccag ctgtctgagt tgagcgtgag tttgaagcaa cgtatctgca
     3121 atatactttg attcatcaaa ctctttggcc atatagcaga acgcctggag agactccggc
     3181 tgcgtccccg cactttcgtc acggtgacgt gcagcagcac aaatgatcgc ggttgaatcg
     3241 agcccaccgg aaagacacac gcccactggc acatcacttc gcatacggat acggactgag
     3301 tcttcaaaaa ggtcaccgaa agtcgccgcg ggatcaggag cgatggtttt cggcaaggca
     3361 tcaagtgtcc aaaacgtcca ttgatgccac gcaccatcta atccgacttc aaacccgcta
     3421 cctggaggaa tctgctcaat cccgtcgtag aatgtctcgt tatgactgtc cagacggcct
     3481 tccaatagaa atctggacgc aattcgccaa ttgatcccta cccgttgata gcccgatgca
     3541 cgcagtgcct taatctctga ggcgaattgt atcaccgtgt gatcacggct gtagtacaac
     3601 ggtttgacac caaatcgatc acgtgacccg aaaagccgtc gatgtcggcg atcataaatg
     3661 acgaacgccc acatgccgtt tagcttcggg aggcactctc gcccccactc ccggtatgcg
     3721 gcgagcagta cttcgctatc tccgctcgat cgaaactgat gccccagctt gcggagttca
     3781 tcccggagtt cgacatagtt gaagatttcg ccattgaaca ccaggacata ctgcccatcc
     3841 tggctgacca ttggctgat
//
LOCUS       DAOQPD010000151         3791 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_16481_length_3791_cov_18.887045, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000151 DAOQPD010000000
VERSION     DAOQPD010000151.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 3791)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3791)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3791
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_16481_length_3791_cov_18.887045"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..479)
                     /locus_tag="PK063_18400"
     CDS             complement(<1..479)
                     /locus_tag="PK063_18400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HMZ99078.1"
                     /translation="MMRAHAVLRRREGLAAWLMVAPALLVTVVFALYPVADSLWLSLH
                     HIFVGIPQLGSPFVGLENYQALLHDPVAHQAFVVTLGFVVLSTLLELACGLIIALVIH
                     ERFRGRGLVRGAILIPWAIPTVVASQLWRYIFNDQYGFANLLLFGDRVTDYIPWLAYP
                     "
     gene            complement(476..1852)
                     /locus_tag="PK063_18405"
     CDS             complement(476..1852)
                     /locus_tag="PK063_18405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HMZ99079.1"
                     /translation="MRWISSRQRIQRPSQSCAVTVSRWIVLLTLIVLTGSTSLGSAES
                     LPGTTATTPKPRVTLRFVSWKPDHARVWDEVLGDFTRAHPQISVVRELAPHSSTAYHD
                     LLTQKLKNRDATVDVFFIDVIWVPEFAEAGWARPLDDKFSPSMRQDFLPAAVEVGRYD
                     THYYGVPSRIDAGLLYYRQDLLEKYGFAAPTTWPELIQQAETILAGERASNPLLQSYS
                     AQFKQYEGLVCNMLEFVEGHGGSLLRPDGTGSTLSSPRALAAVQFVRDRVIGRLTSRA
                     ALTYQEPEALSLFLQGHAIFHRNWPYAWELANNRTRSTIAGQVGVAPLPGFSPGRTAA
                     ALGGWLYGISAYSPHPDEAWALIEFLSSQAVQKKFSREAGIAPSREVLFSDPEVLAHS
                     PQLRNQRSVLHAATPRPRSPVYPAISHLLQRYFSRALALEDIDLAQEAAVTDAHIDRL
                     LALTKAAP"
     gene            2172..2846
                     /locus_tag="PK063_18410"
     CDS             2172..2846
                     /locus_tag="PK063_18410"
                     /inference="COORDINATES: protein motif:HMM:NF040218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin type III domain-containing protein"
                     /protein_id="HMZ99080.1"
                     /translation="MNGLQVSAVSPRRGRLLRMTLGGLLGWALILIAITDAWAVQASP
                     VSLSFSAVQGGPNPASQVVTISKSTSRQVGWKAVDDAAWLSTAPSSGSLTSSAQVVVA
                     VNVSGLAAGTYSGSMKVTLSKGGSLSIPVTLTVASATSTKSTTTVTTATLSWAPNTDS
                     DLAGYKVYMGTTSGLYGTPVDVGNVTTYTAGNLTTGTTYYFSVTAYDQSRNESLHSGE
                     VSKSIY"
     gene            complement(2892..3278)
                     /locus_tag="PK063_18415"
     CDS             complement(2892..3278)
                     /locus_tag="PK063_18415"
                     /inference="COORDINATES: protein motif:HMM:NF013098.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HMZ99081.1"
                     /translation="MKVPFTLGAVWHFGLAVRDPRASAKWFMRVAGLSKQFEYEGGVG
                     IGNANVLIVFSKGKPSPKTVGHVAFHLPTMAALKKALAHLKKLKVQVEDPGDEIGPVA
                     PGSKSMGIWFSDPDGYRWELAVQSKK"
     gene            complement(3291..>3791)
                     /locus_tag="PK063_18420"
     CDS             complement(3291..>3791)
                     /locus_tag="PK063_18420"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012320489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HMZ99082.1"
                     /translation="AVDWVDFEDRMRKLLTRHYGLQGVLLTPAVNSTCHAAALSAYFE
                     GNLHAIDALFTATAGTPFQKRVWNALREIPAGETVSYGDLARRIGQPTAVRAVGLANG
                     ANPVSIVVPCHRVIGADGSLTGYGGGLNRKRWLLNHEKEAMAGSARFAAPSPTAAMVG
                     CASFHR"
BASE COUNT          783 a         1075 c         1199 g          734 t
ORIGIN      
        1 ggataggcca gccaggggat atagtcggtg acgcggtcgc cgaacaggag cagattggcg
       61 aatccgtact ggtcgttgaa gatgtagcgc cagagttgcg aggcaacgac tgttggaatc
      121 gcccagggaa tcaggatcgc gccgcgtacc aggcctcgtc cacgaaatcg ttcatgaatg
      181 acgagggcaa tgatcaggcc gcaggctaac tcgagcaggg tagaaaggac tacaaacccg
      241 agagtcacga cgaacgcttg atgcgcgacc gggtcatgga gcagcgcctg gtaattctcc
      301 aagcccacga atggactgcc aagttgggga atgccgacga agatgtgatg caggctgagc
      361 cagagcgaat ccgcgacggg atataacgca aagaccactg tgaccaggag tgccggtgcc
      421 accatcaacc aggcggccag gccctctcgg cgtcgaagta cggcatgcgc acgcatcatg
      481 gcgccgcttt cgtcaatgcc agaagtcgat cgatgtgcgc atcggtgacg gcagcttctt
      541 gcgcgaggtc gatgtcctcc agcgccaggg cacggctgaa gtagcgctgc aagagatgtg
      601 agatggcggg atacaccggc gaacgcggac gaggcgtggc cgcgtggagg acgctacgct
      661 gatttctgag ctgcggcgaa tgggccagga cctcagggtc ggagaagagc acttcccggg
      721 acggcgcgat gccggcttca cgcgagaatt tcttttggac agcctggctg gagagaaatt
      781 caatgagagc ccaggcttcg tccggatgtg gcgaataggc gctgatgccg tacagccagc
      841 caccgagtgc ggccgccgtc cgtcctggcg agaatcccgg tagaggcgcc acgcctacct
      901 gtccggcaat ggtcgaccgc gtccggttat tcgcgagttc ccaggcatag ggccaattcc
      961 gatgaaagat cgcgtgtcct tgcagaaata gggacagcgc ttccggttcc tgataggtca
     1021 gggcggcacg ggacgtgagc cggccgatga ctcgatcacg gacgaattgc acggcggcca
     1081 gtgcgcgagg cgacgagagg gtggacccgg ttccatccgg tcgcaacaga cttccgccat
     1141 gcccctcgac aaattccagc atgttacaga ccaagccttc gtactgcttg aattgcgccg
     1201 agtagctttg aagcagcggg ttgctcgctc gttcgcccgc caggatggtt tctgcctgct
     1261 ggatgagttc cggccaggtc gtcggcgcgg caaatccgta tttttcgaga aggtcctggc
     1321 gatagtagag cagcccggca tcgatgcggc tcgggacacc gtagtaatgg gtgtcatacc
     1381 ggccgacctc gacggcggca ggcagaaagt cttgtcgcat ggagggggaa aatttatcgt
     1441 cgagcgggcg ggcccacccg gcctctgcaa actccgggac ccagatcacg tcgataaaaa
     1501 agacatcgac agtggcatcg cggttcttca acttctgcgt caggagatcg tgatacgccg
     1561 tcgagctgtg cggggccagt tcgcgcacca ccgagatctg gggatgtgca cgggtgaagt
     1621 ctccgagcac ctcatcccac acgcgtgcat gatcgggttt ccaggagacg aagcgaagcg
     1681 tgacgcgggg cttgggagtg gtggcggtag tcccgggcag tgattccgcg ctcccgaggc
     1741 ttgtactgcc ggtgagtaca atgagtgtga gcaggacgat ccagcgggat accgtgacgg
     1801 cacacgactg tgaaggacgc tggatgcgct gacgtgaaga tatccatcgc atcactctgt
     1861 caggttatac acagtccggt ggggtgatgc aaaaccacca ggccgcagaa gggtgcctgt
     1921 gccaactgcg gcagactgca caatttgggg ctctcaagaa gtgtcacgcc tacaccggca
     1981 tggggcgtca ctgagatggt cgagaaaaac cgttgtgaag acggaggctt gcgaaggtgc
     2041 tccttctggc atgaccactg ctattgtttg tagaggggaa gtggccttgc cgacgtttcg
     2101 acagatcgca gagagagcag ttcaatcaga ggcccgccga ttctcgcggg cgctggtgtg
     2161 aaggaggcaa tatgaatggc ctgcaagtat cagcggtttc gcccaggcgg ggtcgcctgc
     2221 tgcggatgac tcttggtggg ttactgggat gggctctcat cctgattgcc atcacagatg
     2281 cctgggctgt tcaagcgagt ccggtcagcc tcagctttag tgccgtgcag ggcgggccga
     2341 atccggcgag ccaggtcgtg accatctcca agagcacatc gcgtcaggtc ggatggaagg
     2401 ccgttgacga tgctgcgtgg ttgagtacgg ctccttcctc aggaagccta accagttcag
     2461 cgcaggtcgt ggtggcggtc aatgtaagtg gattggctgc cggtacctat agcggctcga
     2521 tgaaggtgac attgagtaaa gggggaagtt tgtccatccc cgtcaccctg acggtcgcgt
     2581 cggcaacgtc cacaaaatcg acgacgaccg tcacgacggc aaccctttcc tgggcgccca
     2641 atacggatag tgacctcgcc gggtacaagg tgtatatggg cacgacctcc ggtctgtacg
     2701 gtacgccggt agacgtcggg aatgtgacca cctataccgc cggcaactta acaactggaa
     2761 ccacgtatta cttttccgtg actgcgtatg accaaagccg gaatgaaagc ctccactcag
     2821 gcgaagtgag caagagcatc tattgatctc gtgctccttc ccgagttgcc attaccggct
     2881 aagtacacgt cttatttctt gctctgcacg gccaattccc accggtatcc gtcggggtcc
     2941 gagaaccaga tccccatgct cttggatccc ggcgccacgg gcccgatttc atctcccgga
     3001 tcctcgacct gaaccttcag ctttttcaga tgggccaggg cttttttgag tgcggccatc
     3061 gtgggtagat ggaatgccac atggccgacg gttttcggcg atggttttcc tttggagaag
     3121 acgatcagca cattggcgtt tccaattccc acgccgcctt catattcaaa ctgtttgctg
     3181 agccccgcta cccgcatgaa ccacttggcg cttgcgcgcg ggtcacgaac cgccagcccg
     3241 aaatgccata ctgcgccgag cgtaaatgga accttcatat ccgtttcctc ctaacggtga
     3301 aatgaggcac atcctaccat ggcggcggtg gggcttggcg ctgcaaaacg cgcggagccc
     3361 gccatcgcct ccttctcatg gttgagcagc caccgtttgc ggttgagtcc accgccgtag
     3421 ccagtgaggg agccgtcggc gccgattacc cggtggcagg gaacgacgat gctgacgggg
     3481 ttcgcgccat tggcgagccc gactgcgcgc accgccgtcg gttgcccgat gcgtctcgcc
     3541 aggtcaccgt aactcaccgt ttctcctgcg ggaatttcgc gcagcgcgtt ccagacgcgt
     3601 ttctgaaacg gggtgcctgc cgtcgcggtg aagagcgcgt cgatggcgtg gagattgccc
     3661 tcgaagtacg ccgacagggc cgccgcatgg cacgtggaat tgacggccgg cgtcaggagc
     3721 acgccctgta aaccatagtg gcgcgtcaac agtttccgca tgcgatcctc gaaatcaacc
     3781 caatcgaccg c
//
LOCUS       DAOQPD010000152         3712 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_17098_length_3712_cov_32.889527, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000152 DAOQPD010000000
VERSION     DAOQPD010000152.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 3712)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3712)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3712
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_17098_length_3712_cov_32.889527"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(8..487)
                     /locus_tag="PK063_18425"
     CDS             complement(8..487)
                     /locus_tag="PK063_18425"
                     /inference="COORDINATES: protein motif:HMM:TIGR00738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HMZ99083.1"
                     /translation="MLKLSKKADYGLMALQHIASNQYGDVAHARVVNTKEIAEEYHIP
                     VELLAKVLQTLSKSGIIESHNGPKGGYLLGKNPREITIAHVLESLEGPLGIMDCSHEK
                     DGDACMQREHCNIRTPLLKIQNSIYQLLNNMTLQDMLGGTPLITIQSVATEQQGVER"
     gene            701..1117
                     /locus_tag="PK063_18430"
     CDS             701..1117
                     /locus_tag="PK063_18430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="HMZ99084.1"
                     /translation="MGGTNPYIEKADVELPSKAYTVTFVFPDKTEKKVEVQPDKIPYG
                     PTGLPGSILDIAMGNDIDLEHVCGGVCACSTCHVMVKKGLETCNEGTDDEFDQLDEAP
                     ATTLQSRLGCQCVPNGTTDVTVEIPAINKNLAKEGH"
     gene            complement(1145..1843)
                     /locus_tag="PK063_18435"
     CDS             complement(1145..1843)
                     /locus_tag="PK063_18435"
                     /inference="COORDINATES: protein motif:HMM:NF013161.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HMZ99085.1"
                     /translation="MAEPTQLAEVVSLTALTPHTTELVLRPIESPLPFKPGQWISLQL
                     PIGDHPPLNRAYSLAEPPTSKGHLTLVFDHVPGGQGSGYLSSLKPGDRLPLSGPYGHF
                     VLPEPEMQHLLLIGRYSGLVPLRCMIRALAEQKTLPATTLIAHAPTASEQLYHDEFTA
                     LAARHSHFQYLPFVSETPDGHVGTLEVIKQLAGNGRRVTPMIAGIKAFARPLRSLFMD
                     LGFDRREVKLETYD"
     gene            1961..3376
                     /gene="gltX"
                     /locus_tag="PK063_18440"
     CDS             1961..3376
                     /gene="gltX"
                     /locus_tag="PK063_18440"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009332 - glutamate-tRNA ligase complex
                     [Evidence IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HMZ99086.1"
                     /translation="MSQVRVRFAPSPTGFLHIGGVRTALFNWLFARQQNGVFILRIED
                     TDQDRSTDASIQAILDGMRWVKLDWDEGPFRQTERMDLYRSHALRLFEQGHAYWCVCT
                     PEELEARRKEAEAKGGSPRYDGRCRNLGLAKPTSDAALRFKAPQDGQTVVDDLIKGRV
                     VFDNQILDDVIILRSNGFPTYNFSVVVDDALMGITHVVRGDDHLTNTPRQIPIFQALG
                     FPLPRFGHLPMILGSDKTRLSKRHGATSIMAYKEMGYLPEAMVNYLVRLGWSHGDQEL
                     FSRDELIEKFSWKNVQTSPAVFNPDKLLWLNAEYLKTNPPQQVAEALVPLLEQTDLKD
                     EVRAVSTEWLAQLVVLVKERTKTLVEMVHWVRPYFGEAVSFDEEAAKKFLTPAQAPIL
                     TKLVERFEALPVFSKHEWEEAFKKLVEEAGIKMGQLAQPVRVALTGRTASPGLFEVME
                     VLGRERTLIRLRKGIEQAARS"
     gene            3444..3517
                     /locus_tag="PK063_18445"
     tRNA            3444..3517
                     /locus_tag="PK063_18445"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3476..3478,aa:Gln,seq:ctg)
     gene            3571..3644
                     /locus_tag="PK063_18450"
     tRNA            3571..3644
                     /locus_tag="PK063_18450"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3603..3605,aa:Gln,seq:ttg)
BASE COUNT          807 a          963 c         1111 g          831 t
ORIGIN      
        1 gggaacttca tcgctcgact ccttgttgtt ccgtcgcgac ggattgaatg gtgatgagag
       61 gggtgcctcc caacatatct tgcaaggtca tgttgttcaa aagctgatag atgctgttct
      121 ggattttcag gagcggggtc cggatgttac agtgttcacg ttgcatgcag gcatcaccgt
      181 ctttctcatg cgagcaatcc atgatgccga gtggcccctc cagactttcg aggacgtgag
      241 cgatggtgat ctcccgagga tttttcccga gtagataccc acccttgggg ccgttgtggc
      301 tttcaataat cccgctcttc gaaagcgtct gaaggacttt tgcgagcagt tcgaccggaa
      361 tatgatattc ctcggcgatt tccttggtgt tcaccactcg ggcatgagcg acatcgccgt
      421 actggttgga ggcgatgtgc tgcagtgcca ttaatccgta gtctgctttt ttagataatt
      481 tcagcatggc ctattgccga tctttaaagt cggagactat aatgatctcc gatcaaatga
      541 gtcgtacaaa agctatcatg tgatctttta tactgtcaag ggcgccggtg agccaaagtg
      601 tagaaagagg tggcttcccg agggcgcggc ccgatggtcg gctgatcgtc cattgcactt
      661 gtcattgaaa ataaactgaa aagaaaagag gctgcgcacc atgggtggaa cgaatcccta
      721 tattgaaaaa gcagacgtcg aattgccgtc gaaggcgtat accgtcacgt tcgtattccc
      781 ggacaagacc gaaaagaagg tggaagtgca gccggacaag attccctacg gtccgacggg
      841 cctaccgggc agcattctgg atatcgccat ggggaacgac atcgacctgg agcatgtgtg
      901 cggaggggtc tgtgcctgct ccacgtgtca tgtcatggtg aaaaagggtc tggagacgtg
      961 caatgagggg acggatgatg agttcgatca gttagacgag gctcccgcca cgacgctgca
     1021 atcccggctt gggtgccagt gcgtgccgaa tgggacgaca gacgtcaccg tggagattcc
     1081 cgcgatcaat aagaatctgg cgaaggaagg tcattgattc agcaagacac agcctgatga
     1141 ggcttcaatc gtacgtttcg agtttcactt cccgtcgatc aaaccccagg tccataaaca
     1201 ggctgcgcaa cgggcgggca aaggccttaa tccccgcgat catgggcgtg acgcggcggc
     1261 cgtttccagc cagttgtttg atcacctcca gagtccccac atgcccgtcc ggggtctcgc
     1321 tcacaaacgg caggtactga aaatgggagt gcctcgctgc cagcgctgtg aattcatcat
     1381 gatagagttg ctcgctggcg gtgggggcgt gcgcaatcag ggtggtcgcg ggcaacgtct
     1441 tctgctctgc cagtgcgcgg atcatacagc gcagtggaac aaggcctgaa taacgaccga
     1501 tcaacagcaa atgttgcatt tccggctctg gcaacacgaa atgaccatag ggccccgaga
     1561 gggggaggcg atccccgggc ttgagtgacg aaagatagcc cgacccttga cctcccggaa
     1621 catgatcgaa caccagtgtg agatgtcctt tggaggtcgg gggctctgcc aaagaatagg
     1681 cccgattcaa tggggggtgg tctccgatcg gcaattggag cgagatccac tggccgggtt
     1741 tgaagggcag gggagactcg atcggacgga gcacgagttc ggtggtatgg ggagtcaacg
     1801 ccgttagcga gacgacttca gcaagttgtg ttggttcagc catggactgt tcttagcaaa
     1861 aacagattca gaatggaaca gccccgttct gtacatcgtt ccggtgccat gatatagata
     1921 cccccccgtt aatttctccc acacacacta cggtgacgcg atgagtcagg tcagggttcg
     1981 atttgcgccc agtccgaccg gcttcctcca tatcggcggg gtgcggacgg ccttgttcaa
     2041 ctggctgttt gcgcggcagc agaacggcgt gttcattctc cgcatcgaag ataccgacca
     2101 ggatcggtcg accgatgcat cgatccaagc tattctcgat ggcatgcgct gggtcaaact
     2161 ggattgggat gaaggtccct ttcggcagac cgaacgcatg gatctctatc gtagccatgc
     2221 tctgcggctg tttgagcagg gccatgccta ctggtgcgtg tgcacaccgg aggaactgga
     2281 ggctcgccgg aaagaagcgg aggccaaggg aggatcaccc agatatgacg gtcggtgccg
     2341 aaacctgggt ctcgccaagc caaccagtga cgcggcgctc cggttcaaag cgccgcagga
     2401 cggtcagacg gttgttgatg acctgatcaa gggccgggtg gtgttcgaca atcagatcct
     2461 ggatgacgtc atcattctca ggtcgaacgg ctttcccacc tataacttct cagtagtggt
     2521 ggacgacgcg ttgatgggca tcacacacgt ggtgcggggg gacgaccatc tcacaaacac
     2581 cccgcgccaa atccccattt ttcaggccct cggattcccg ctgccacgct tcggccactt
     2641 accgatgatc ctgggttcgg acaaaacgcg gctgtcgaag cgtcacggcg cgacgtcgat
     2701 catggcttac aaggaaatgg gctatctgcc ggaggccatg gtcaactatc tcgtccggct
     2761 tgggtggtcg catggggatc aagagctctt ttcgcgagac gaactgatcg agaagttctc
     2821 ctggaagaac gtccagacct ctccggctgt cttcaaccct gacaagttgc tgtggctcaa
     2881 tgccgaatat cttaagacca atccgcctca gcaggtggcg gaagcgctgg tgccgttgct
     2941 cgaacagacc gacctcaaag acgaggtccg cgcggtctcg acggagtggc tcgcgcagct
     3001 cgtggtcttg gtgaaagagc ggactaagac attggttgaa atggttcatt gggtgaggcc
     3061 ttactttggc gaggcggtgt cgtttgatga ggaggccgcg aaaaaattcc tgactccggc
     3121 tcaggcccct atattgacta agctggtgga acgctttgag gcgcttccag tcttttccaa
     3181 gcacgagtgg gaagaggcgt tcaagaagtt ggtcgaggaa gcgggaatca aaatggggca
     3241 gttggcccaa ccggtgcggg ttgccttgac tggccggacg gcgagtcccg gcttgttcga
     3301 agtgatggaa gtgctcggcc gggaacgtac gttgattcga ttgcgcaagg ggatcgagca
     3361 ggccgccaga tcctgattgg ctgttcaaga atcacgctcg atcttgacgc aatggagagg
     3421 cttatattac tgtgtggacc ggttggggga tcgtctagcg gtaggacgtc agtctctgga
     3481 tctgactacc taggttcgat tcctagtccc ccagccaaaa tcttttccac gccttgctct
     3541 tcagctcgat gtctcggttc cgtaccgcgc tgggggatcg tctagcggta ggacgccagc
     3601 ctttggagct ggctacctag gttcgattcc tagtccccca gccaaactta tctctccaca
     3661 atttcagtaa cttgcgagcc ttccagatcc cggttcgatt tatgagccgg gg
//
LOCUS       DAOQPD010000153         3687 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_17302_length_3687_cov_18.762665, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000153 DAOQPD010000000
VERSION     DAOQPD010000153.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 3687)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3687)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3687
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_17302_length_3687_cov_18.762665"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            212..1333
                     /gene="wecB"
                     /locus_tag="PK063_18455"
     CDS             212..1333
                     /gene="wecB"
                     /locus_tag="PK063_18455"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HMZ99087.1"
                     /translation="MSRSLIYLVAGARPNFMKIAPIVRALEARSDRFEYKIIHTGQHY
                     DREMSDVFFDELGIPKPDYHLEAGGGSHATQTAKIVVAFEEICRQVRPDCVLVVGDVN
                     STLACSIVAKKQVIPVAHVEAGLRSGDMRMPEEINRLVTDSISDWFFCTEPSGVENLL
                     REGKVKDVVFHVGHVMVDNLLYQRDKLDASDKSGLTTEAIKAKQPKYGVVTLHRPSNV
                     DDEPTLRGIVGALRQIAEQLPLIFPVHPRTRGNLERFGLDLGPNVLLTKPQSYMEFLN
                     LWKDAALILTDSGGLQEETTALGIPCLTLRENTERPVTADEGSNVLVGPNPQRILEEA
                     AKVLSGAGKQGRRPALWDGKAAERIVAELDRLLEWSTSV"
     gene            1450..2553
                     /locus_tag="PK063_18460"
     CDS             1450..2553
                     /locus_tag="PK063_18460"
                     /inference="COORDINATES: protein motif:HMM:NF012695.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NDP-sugar synthase"
                     /protein_id="HMZ99088.1"
                     /translation="MAKGMILAAGQGTRVRPLTKNIPKPMVPILGKPLMEYLIEHLAR
                     HDIRQIMVNVAFNHYKIENFFGDGHRWGVEMGYSYEGKRDHGDIVPKPLGSAGGMRRI
                     QDFGGFFDETTLVLCGDAIVDLDITAAIAEHKAKGAIATVVTVEVPLEQVKNYGVVVA
                     DEQGRVMSFQEKPKPEEAKSRLASTGIYIFEPAVLDYIPPGVEFDIGSQLFPKLVELG
                     VPFYAQRHAFKWIDIGRLTDYWDVLQRVLRGEVAQMHMPGQEVAPGVWVGLNTSIAWE
                     SVQLVGPVYIGSNVRIEPGVSVIGPAWIGHGSHLRSGSRVVRSILFEYTRVAEGMVFT
                     EKILSPQYCVDRSGEAVYVGDDTCPLRWGDARA"
     gene            complement(2830..3513)
                     /locus_tag="PK063_18465"
     CDS             complement(2830..3513)
                     /locus_tag="PK063_18465"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99089.1"
                     /translation="MPKSYYLPTDDSGKIEVLEMLAAKLPAYKDVLYISTEEIEAVQA
                     DAIAMRYILSVFNQMQNNAKQWTAYKNLIRDGGASKAALPVFPSLPDPVPPTVPPGII
                     PRLTSLVTRIKAARNYTDVIGQDLGIVGTVKVVDPATWKPTLDTRIEAGRPYILWSKG
                     KADSLEIWVDRGNDKGFVFLDISTDYRFADNAPMPNTVALWKYKAIYRLRDQQVGQWS
                     NVHAVPVGG"
BASE COUNT          678 a          933 c         1254 g          822 t
ORIGIN      
        1 agaaaatcgt gtccggcggc gtgttcaccg acgtgaagag cttctacgat ccggctgcca
       61 tcgaggcggc gggggccaag gtgtggcggc tgtaagcgcg aggggccttg cggctgtgta
      121 acgtcgcaag gcgacaatta tttctttgtg ctgcctcagg cgggcgcgcg ataatgcgcg
      181 cccgcactgt ttgtactcgc cggagctttc catgtctcgc tcacttattt accttgttgc
      241 cggagcccgg ccgaacttca tgaagattgc accgatcgtt cgcgcgctgg aggcgaggtc
      301 ggatcggttt gagtacaaga tcatccacac cggccagcac tatgaccggg agatgagcga
      361 tgtcttcttc gacgagttgg gcattcccaa gcctgactac caccttgaag ccgggggggg
      421 cagccacgcg acccagacgg ccaagatcgt ggtggccttc gaggaaatct gcaggcaagt
      481 ccggccggat tgcgtgctgg ttgttggcga cgtcaattcc acgctggcgt gctcgattgt
      541 cgcaaagaag caggtgatcc ccgtggctca cgtggaggcg ggcctgcgta gcggggacat
      601 gcggatgccc gaggaaatca accgtctcgt caccgacagc atctcggact ggttcttctg
      661 caccgagccc tcgggtgtcg aaaacctgct gcgtgagggt aaggtcaagg acgttgtttt
      721 ccatgttggt cacgtgatgg tcgataatct cttgtaccag cgggacaagc tcgatgcgtc
      781 ggataaatct ggcttgacga ccgaagccat caaggcgaaa caacccaagt acggtgttgt
      841 aacccttcac cggccatcca atgtggatga cgagccgacg ctgcgaggca tcgtcggcgc
      901 gctccgtcag attgccgaac agctgcccct gatctttccg gtgcatcctc gcacccgtgg
      961 caacctggag cgcttcggcc tggatcttgg cccgaatgtg ctgctgacca agcctcagtc
     1021 gtatatggag ttcctgaatc tgtggaagga cgcggcgctg atcctcactg atagtggcgg
     1081 ccttcaggag gaaaccactg ccttgggcat tccctgcctg acgctacgcg agaacactga
     1141 gcgcccggtg acggcggacg agggtagcaa cgtgcttgtc ggacccaacc cccagcgcat
     1201 tctcgaagaa gctgccaagg tgctctctgg cgcgggcaaa caggggcgcc gtcccgcctt
     1261 gtgggacggc aaggccgccg agcgcatcgt tgccgaactg gatcggttgc tggaatggag
     1321 tacgtcagtt tagtttattg cagatattgg gaatttagat tataggaatt cagaaactcc
     1381 tatctttcgt aaatgttgtt tggaaatagt taggctgata tttatggcgc ttatatagcg
     1441 gagagtgtat tggcaaaagg catgatcctg gccgcaggcc agggcacgcg ggtccgcccg
     1501 ctcacaaaga acatccccaa acccatggtg cccatcctcg gtaagccgct gatggaatac
     1561 ctgatcgaac atctggccag gcacgatatt cgccagatca tggtgaacgt ggcgttcaac
     1621 cattacaaga tcgagaattt tttcggcgac gggcatcgct ggggtgtgga gatggggtat
     1681 tcctacgagg gcaagcggga tcatggcgat attgtgccaa agcccctcgg ctcggccggc
     1741 ggcatgcggc gaattcagga cttcggtggt ttcttcgatg agaccacact ggtgttatgt
     1801 ggtgacgcga ttgtcgatct ggacattact gctgcgattg cagagcacaa ggccaaaggg
     1861 gcgattgcca cggtggtgac agtcgaggtg ccgcttgagc aggtgaaaaa ttacggtgtg
     1921 gtagtggcgg acgagcaggg acgagtgatg tcctttcagg agaagcccaa gccggaagag
     1981 gccaaatcgc gtttggcgag taccggtatc tacatctttg agcctgcggt gcttgactat
     2041 attccccccg gcgtggagtt cgatattggc agccagttgt tcccgaaact ggtggagttg
     2101 ggggtgccgt tctatgctca gcggcatgcg ttcaaatgga tcgatatcgg caggctgacg
     2161 gattattggg atgtgttgca acgggtgctg cgtggtgaag tggctcagat gcacatgccg
     2221 ggccaggagg tggcgccagg ggtgtgggtt gggttgaata cgtcgattgc gtgggaaagc
     2281 gtgcagctcg ttgggccggt ttacatcggg tccaatgtgc gtatcgagcc cggcgtgtcc
     2341 gtcatcgggc cagcgtggat cgggcacggt agccatctcc gctcgggttc gcgcgtcgtg
     2401 cggagcattc tttttgagta cacccgcgtg gcggagggca tggtcttcac ggagaagatc
     2461 ctgtcacccc agtattgtgt cgaccgcagt ggtgaagcgg tatatgtcgg tgacgatacc
     2521 tgcccgttgc gttgggggga tgcccgtgcg tgagcgtgat gcagtgctgc atgcttcaga
     2581 gccttgcagg cggcacaggc ttgttgcgag gcgttgaagg gttcatctat gggatctgtt
     2641 ttttggggat tccggaacgc tttaggcggt ttgcgttgcg gctcggtgat ctattccaag
     2701 tggcggatcg acaatgcgcc gctgcgctgt tttttgcgca caggcggaga aagccgctca
     2761 gttaggggag agcgagccgg gcatgtgtgc cgcggctcgc ggcgtgttgc ctgagatgat
     2821 tcgccggatt tatccgccga cgggcaccgc gtggacgttg ctccactggc cgacctgttg
     2881 atccctgagc cggtagatgg ccttgtattt ccagagggcg acggtgttgg gcatgggggc
     2941 gttgtcggca aagcggtagt cggtgctgat gtcgaggaac acgaagccct tgtcgttgcc
     3001 ccggtccacc cagatttcga gggagtcggc cttgcccttg gaccacagga tgtagggccg
     3061 gccggcttcg atgcgggtgt cgagggtggg tttccaggtg gcgggatcga cgaccttgac
     3121 ggtgccgacg atgccgagat cctggccgat cacgtcggtg tagttgcggg cggccttgat
     3181 gcgagtaacc agggaggtga ggcggggaat gatgcccggc ggaacggtgg gcggcaccgg
     3241 gtctggcagg ctggggaaga cggggagcgc cgccttgctg gcgccgccgt cccggatgag
     3301 gttcttgtag gccgtccatt gcttggcgtt gttctgcatc tggttgaaga cgctgaggat
     3361 gtagcgcatg gcgatggcgt cggcctggac ggcttcgatt tcttcggtgc tgatgtagag
     3421 cacgtctttg taggccggta gtttggcggc aagcatctcc agcacttcga tcttgccgct
     3481 gtcgtcggtc gggaggtagt agctcttggg catgatgtct ctccagtctc aataggggta
     3541 gatcaggtca tcgggcaggt ctggcacggt gtgccgcacg cccggaaacg tgtgatgaag
     3601 cgtggggatg tgttgtgtca ggtcgggcac ctccggaatg tgttgaaaag atggttgcgg
     3661 aaccccacgg acacgatgtg ggagcgt
//
LOCUS       DAOQPD010000154         3636 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_17751_length_3636_cov_25.451829, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000154 DAOQPD010000000
VERSION     DAOQPD010000154.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 3636)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3636)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3636
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_17751_length_3636_cov_25.451829"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(112..513)
                     /gene="rplL"
                     /locus_tag="PK063_18470"
     CDS             complement(112..513)
                     /gene="rplL"
                     /locus_tag="PK063_18470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014449069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HMZ99090.1"
                     /translation="MSAAAGTKLSQEELIKAIEGMSVLELADLVKGLETRFGVTAAAP
                     VAVAAAGGGGAAAAPAEEKTSFDVILASAPADKKIQVIKVVRELTSLGLKEAKDLVEG
                     APKPIKSGATKEEADTMKKKLEESGAKVEIK"
     gene            complement(541..1047)
                     /gene="rplJ"
                     /locus_tag="PK063_18475"
                     /pseudo
     CDS             complement(541..1047)
                     /gene="rplJ"
                     /locus_tag="PK063_18475"
                     /inference="COORDINATES: protein motif:HMM:NF000955.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
     gene            complement(1079..1771)
                     /gene="rplA"
                     /locus_tag="PK063_18480"
     CDS             complement(1079..1771)
                     /gene="rplA"
                     /locus_tag="PK063_18480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HMZ99091.1"
                     /translation="MGKKMTAAQEKIEPRFYELKEAVEAVKQAAFAKYDESVDLAIRL
                     GVDPKRSDQMVRGTTALPHGTGKKLRVLVFAKGEKEQEARQAGADYVGSDDLMEKIKG
                     GWMDFDCAISTPDLMASVGKLGKVLGPRGLMPNPKTGTVTFEVGKAVSEIRKGRVEFK
                     VEKAGIVQVPVGKVSFDVQKLYDNAQAVLESVVKAKPSSCKGRYIKSVTMSSTMGPGV
                     KLDPVALSKLWS"
     gene            complement(1816..2238)
                     /gene="rplK"
                     /locus_tag="PK063_18485"
     CDS             complement(1816..2238)
                     /gene="rplK"
                     /locus_tag="PK063_18485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HMZ99092.1"
                     /translation="MAKEVSAQIKLQIPAGKANPAPPVGPSLGQHGVNIMEFCKQFNA
                     KTQKDGDSIIPVIITVYKDRSFTFIMKTPPASDLLKKAAGIIKGSGVPHKDKVGKVSQ
                     AQVREIAQKKLSDLNAADLEGAIKIIQGTARSMGITVQ"
     gene            complement(2314..2856)
                     /gene="nusG"
                     /locus_tag="PK063_18490"
     CDS             complement(2314..2856)
                     /gene="nusG"
                     /locus_tag="PK063_18490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HMZ99093.1"
                     /translation="MMSNKNWYVIHTYAGFEGRVKTSLLERANQMGLTERLGQVLVPT
                     EDVIEIKDGKRRTSRRKFFPGYVLVELEAPLADETLQMIKETPKVTGFVGGGAQPTPL
                     SSEEVDSLLKQVDAGAAGPREQVRFIKGDNVRIVDGPFLGFNGAVDDVDADHSRVKVF
                     VSIFGRSTPVELGFLQVERI"
     gene            complement(2926..3120)
                     /gene="secE"
                     /locus_tag="PK063_18495"
     CDS             complement(2926..3120)
                     /gene="secE"
                     /locus_tag="PK063_18495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HMZ99094.1"
                     /translation="MFQRLIASVREFIDGVRGELRKVSFPTKTETIGATTVVIVFCIL
                     MSLYLSMMDSVLGWLMRKVI"
     gene            complement(3213..3287)
                     /locus_tag="PK063_18500"
     tRNA            complement(3213..3287)
                     /locus_tag="PK063_18500"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3252..3254),aa:Trp,seq:cca)
     gene            complement(3344..3493)
                     /gene="rpmG"
                     /locus_tag="PK063_18505"
     CDS             complement(3344..3493)
                     /gene="rpmG"
                     /locus_tag="PK063_18505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013271142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HMZ99095.1"
                     /translation="MREIIDLACTVCKQRNYTTRKNKKNDPDRLERNKFCKFCRKHIA
                     HKEVK"
BASE COUNT          766 a         1189 c          841 g          840 t
ORIGIN      
        1 cgacaaactc cgaaagagtc gattccgaca ttcgttagcc ctccaagctc ataagcagat
       61 gaacgcctcg cgccatctca acggacaatc acactgcagc gcccgaaaca attacttgat
      121 ttcgacttta gctccgctct cttcgagctt cttcttcatc gtgtcggctt cttccttggt
      181 ggcgccggac ttgatgggct tcggtgcgcc ttcgaccagg tccttggctt ccttgagtcc
      241 gaggctggtg agctcgcgca ccaccttgat gacctggatc ttcttgtcgg ccggagcgct
      301 cgccaaaatc acgtcgaatg acgtcttttc ttcggccgga gccgctgccg caccgccgcc
      361 acccgctgcc gccacggcca ccggggccgc cgctgtcacg ccgaaacgag tctcgagacc
      421 cttcaccagg tcggccaatt ccaacacgct catgccttcg attgccttga tcaattcttc
      481 ctgtgacaac ttggttcctg ctgctgctga catgtcgccc tcccctttct ttttatcctg
      541 aatggctgca atgactcgca caaacttgct caatactcca cttaacgcat agaccacgcc
      601 gcgtatcgga ccctgcatgg ccgatagcaa cattgcaatc aacacttcct tcttcggcaa
      661 ttgcgcaatg gctgcaaggt ctgcagcctg caccaacttg ccctctaaca cgccgacggt
      721 caccttgatc ttctcagatc gcttttcggc ctgaataaaa tcgcgcaaga ttttcgccgg
      781 caaaaccgga tcgtcgtatc cgatcaccag cccggtcggg cccttgaagt gatcttttgc
      841 atcggcgagg atcgtaccgg tcgaggcgcg gacggccagg gtattcttga tgacacagta
      901 ctcggcttta gccccgcgca actgccttcg cagctcggtc atttgattga cgggcatccc
      961 ggcgcattcc gtcaaaatgg ccaagcgggc gcggccaaac ttctctgtca actccgcgat
     1021 cgctgttgcc ttctcttctt tcttcatacc tctcccctta ctgagaacct gtccgttctc
     1081 aactccacaa cttcgacaac gccacaggat ccagcttcac gccaggcccc atcgtgctcg
     1141 acatcgtcac actcttgatg taccggccct tgcaggatga cggcttcgcc ttgaccaccg
     1201 actccagcac tgcctgcgca ttgtcgtaca gcttctgaac atcgaacgac accttgccaa
     1261 ccggcacctg gacgatgccg gctttttcca ccttaaactc gacacggcct ttgcgaatct
     1321 cgctcacggc cttccccacc tcaaacgtca cagtgccggt cttcggattg ggcatgaggc
     1381 cacggggacc aagcacctta ccaagcttac cgacagaggc catgagatca ggggtggaaa
     1441 tcgcacaatc gaaatccatc catccgccct taattttttc catcagatca tcagagccta
     1501 cgtaatcagc cccggcctgc cgcgcttcct gctccttttc acccttggcg aatacgagca
     1561 cccggagctt tttgccggtg ccatgcggga gcgccgtggt tccacgtacc atttgatccg
     1621 atcgcttggg atccacaccc agccggatcg ccaggtcgac ggattcatca tacttggcaa
     1681 aggctgcttg cttgacggcc tcaaccgcct ccttcaactc ataaaacctg ggctcaattt
     1741 tctcctgagc cgcggtcatc ttctttccca tactgctgct ccttcacatc cgccggaggt
     1801 tcactctgca cgaatttact ggacggtgat gcccatgctg cgcgctgtgc cctgaataat
     1861 cttgatggcg ccttcaagat cagccgcgtt caagtccgac aacttctttt gcgcgatttc
     1921 ccgaacctga gcctgactga ccttgcccac cttatccttg tgcgggacgc ccgatccctt
     1981 gatgataccc gcggccttct tgagcaagtc cgacgccgga ggcgtcttca tgatgaaggt
     2041 aaagctccgg tccttgtaga ccgtaatgat caccgggatg atgctatccc catctttttg
     2101 ggtcttcgca ttgaattgct tgcagaactc catgatgttc acaccgtgtt ggcccaacga
     2161 aggaccgacc ggcggagcag gattggcctt accggccggg atctgcaatt taatttgagc
     2221 tgatacttcc ttggccatga gttactccct gagaactgcg gactgcgcga ggaccggaaa
     2281 tagctcccag cccactccca ccaatccagt gactcaaata cgttcgacct gcaagaatcc
     2341 aagctcgacc ggagtagacc ggccgaaaat actgacaaac accttcacgc gactgtgatc
     2401 ggcatccaca tcatcgacgg cgccattgaa gcccaggaac ggaccatcca cgatacgaac
     2461 gttgtcccct ttaatgaacc ggacttgctc tcgaggtccg gccgctccgg catcaacttg
     2521 cttcaacaaa gaatcaactt cttccgagga gagcggcgtt ggctgtgccc ctccaccaac
     2581 aaaccccgtg actttcgggg tctccttgat catctgcaag gtttcgtcag ccaacggcgc
     2641 ttccagctcg acgaggacat agcccggaaa aaattttcgc cgggaggtcc gtcgcttgcc
     2701 atccttgatt tcgatgacat cttccgtagg aaccaggacc tgcccaagtc gctcggtgag
     2761 ccccatttga tttgcgcgct cgaggagact ggtcttcacg cgaccctcaa accccgcata
     2821 ggtatggatg acgtaccagt tcttattgct catcatctcc tctcagctga acatcagcat
     2881 cgtatcgtcc gggcaatgcc ggacctgtcc agccgcacca cgcaactaaa taaccttgcg
     2941 catcagccag cccagcacgg aatccatcat cgacagatac aaggacatga gaatgcagaa
     3001 cacaatcacg accgtggtag caccgatcgt ttccgttttc gtcggaaaag aaaccttccg
     3061 cagttctccg cgcacaccat cgataaattc tcgaacagag gcaatcaatc gctgaaacac
     3121 ggttcaaatc ctctcgtaga acttttcgac tgccagactc ccccagacgg accaaccacc
     3181 ctacacatca ccccactaag aagcatccgc tttggcaggg gcactaggat ttgaacctag
     3241 actctcggtt ttggagaccg atgtgctgcc gttgacacca tgcccctccg ctcggaacat
     3301 gagcgccgcg gggcccgcaa cgaggccccg cgccccacac cccttacttc acttccttat
     3361 gggcaatgtg tttgcggcaa aacttgcaga acttgtttcg ctccagccgg tccggatcgt
     3421 ttttcttgtt cttgcgggtc gtataattcc gctgcttaca gaccgtacag gccaagtcaa
     3481 tgatttctcg catgtcgtat acccgtgaag cgtgtaacgt gaagccggag agtgggattg
     3541 tctccgcgct cgaaacgcct gacgcttaac gcctccctct actaagctag aatttccgta
     3601 acgacgcccg agccgacagt cttgccgcct tcgcgg
//
LOCUS       DAOQPD010000155         3547 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_18528_length_3547_cov_21.637743, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000155 DAOQPD010000000
VERSION     DAOQPD010000155.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 3547)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3547)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3547
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_18528_length_3547_cov_21.637743"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..578)
                     /locus_tag="PK063_18510"
     CDS             complement(<1..578)
                     /locus_tag="PK063_18510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HMZ99096.1"
                     /translation="MRTIRYTSWLLAVLLTAAGCNNEQASSGGQAPPPPEVGVAQVIS
                     KPVQQWDEYTGRISAIDTVELRPRASGYVQRVAYKEGQDVKQGDLMFLIDPRPYRAAL
                     ENAQAQLARARVAQQLETIRNKRAQALIDDNAISHEELDLRRAAQAQSAADVHAAEAA
                     VATAKLNLSFTEVRAPVSGRASRALVTVGNLAT"
     gene            759..1250
                     /locus_tag="PK063_18515"
     CDS             759..1250
                     /locus_tag="PK063_18515"
                     /inference="COORDINATES: protein motif:HMM:NF024854.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HMZ99097.1"
                     /translation="MKRVNVARRMKPKETTCVSPCISTLPRHRLVELLWSFAPAYQRW
                     SESLLVEKGLSPQRLRILGSIHERGPRIMSELKKELGVTATNVTALVDSLENDGLVVR
                     RRHPTDRRATVIELSDKVMRELSPRCTEYKEQVAELFSDLSDQECKAFVKTLEKLWSR
                     LQG"
     gene            complement(1527..1697)
                     /locus_tag="PK063_18520"
     CDS             complement(1527..1697)
                     /locus_tag="PK063_18520"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99098.1"
                     /translation="MDEVRGLQFTARRLATQLDLLIQALEDAKPSQEIQELCREGRVV
                     LDYATTVLGGDE"
     gene            complement(1741..2178)
                     /locus_tag="PK063_18525"
     CDS             complement(1741..2178)
                     /locus_tag="PK063_18525"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99099.1"
                     /translation="MLPEMLLFATIHGTQALPVSDKVPYESAEASAKLFSEDEIRVVK
                     GIILDTTAVRLKDGVEFMQMEVETERGPVRVHLGPTWYMNEYHERFDVNKGRLVTAVC
                     SPALVDGRHVLVAAELANADGQQRMRLRHPDGTPAWVGGEHVK"
     gene            complement(2375..2668)
                     /locus_tag="PK063_18530"
     CDS             complement(2375..2668)
                     /locus_tag="PK063_18530"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99100.1"
                     /translation="MPDLTKNEAIIAALESAGYQEIRLTVVPKRFLFSDGRCHTELEF
                     SRNYFDDTTLIALQGQMGEHILPAIKQQPGKKVYVDARGISIIPFTPGRKDKH"
     gene            complement(2779..3261)
                     /locus_tag="PK063_18535"
     CDS             complement(2779..3261)
                     /locus_tag="PK063_18535"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99101.1"
                     /translation="MTNLTSTLRLQHLFISNLLEAAQWIGVEKVEAQRKLRAAKIHLL
                     AHFKLEDTLLYPVLFEAAEKNTELKYTLQFLEKDMAGVSKEVIGFFDQFHISGTHHHT
                     TQDIGNILFLLQTRIRREEDTLFAEFDKLKAAARTIVAVQIPDSRSSILASSHSIHPM
                     "
     gene            complement(3361..>3547)
                     /locus_tag="PK063_18540"
     CDS             complement(3361..>3547)
                     /locus_tag="PK063_18540"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99102.1"
                     /translation="TLTAETLHSYGFPQAPYPSPTYRHFKNHCYFYKMMTFDRRLVAP
                     VSSGIIVNQRASHDVCG"
BASE COUNT          721 a          955 c         1052 g          819 t
ORIGIN      
        1 gtcgccaggt tgccgacggt caccaacgcc cggctcgccc gcccggagac cggggcgcgg
       61 acctccgtga acgacaagtt gagcttggcg gtcgccaccg cagcttcggc ggcatggaca
      121 tccgccgcgc tttgcgcctg cgccgcgcgc cgcaagtcga gttcttcgtg cgagatcgcg
      181 ttatcgtcga tcaaagcctg ggcgcgcttg ttgcggatgg tttccaactg ctgcgctaca
      241 cgcgcgcgtg ccagctgcgc ctgggcgttt tccagtgcgg cgcggtaggg acggggatcg
      301 atcaggaaca tcaagtcgcc ctgtttgaca tcctggcctt ccttgtacgc cactcgctgc
      361 acgtagccgc tggcgcgggg gcgtaattcc accgtgtcga tcgcgctgat gcggcccgtg
      421 tattcgtccc attgttggac cggtttcgaa atcacttgcg cgaccccgac ctcaggcgga
      481 ggtggcgcct ggccgccgct gctggcctgt tcgttgttgc agccggctgc ggtcagaagc
      541 actgccagca gccaggatgt atatcggata gtgcgcatgg tgtacctgtt ggatgatcga
      601 tggtgaacga tgacgtcagt gcaagagtcc ggggttcttc ctcacccctg tcgtgcagta
      661 tccggcacgg tgtgaaacat agtcaatata tgaatgatgc agctatgaat aatttatgat
      721 tgaaaggtgt cgcgttcttg aagtaccgta tctgtacgat gaaacgtgtc aacgttgcca
      781 ggcgaatgaa gcccaaggag acgacatgcg tctctccctg tatctcgacg ttgccccggc
      841 accggttggt tgagcttttg tggagctttg ctcctgccta tcagcggtgg tcggagtcgt
      901 tgctggtgga gaaggggtta tcgcctcagc ggttgcgcat cctcggctcc attcatgagc
      961 gcggccccag gatcatgagc gagctgaaaa aggagctcgg cgtgacggcg acgaacgtca
     1021 cggcgctcgt cgattcgctg gaaaacgatg gattggtggt gcggagacga catcccacgg
     1081 atcgccgggc cacggtgatc gagctctcgg acaaagttat gagagagctc tcgccccgct
     1141 gtacggaata taaagagcaa gtcgccgaac tgttttcaga cctgagcgac caggagtgta
     1201 aagcattcgt gaaaacgctc gagaagctgt ggagtcgatt gcaggggtaa agcacagtcg
     1261 taagaaagag tctttgcagg taccgcagca gaattcagga aggttcgcgg tagcttcgac
     1321 taggccactt ggattcagcc ttgcggtacg ggcgagaggg cggtcgacgc gtcacaagtc
     1381 gcttgaacag gagtaccagg gtggcgagcg acagtattga gaagagacga gcgaacatac
     1441 gatcacgata tccctccacg acgagagtgt caaacacgta cgatccagac gtcatgcttc
     1501 caagccgtgg aatgtccctc tgagtctcat tcatctcctc ccagaacggt agtggcataa
     1561 tccagtacca cccgaccctc tcggcacaac tcctgaatct cctgggaagg cttcgcgtct
     1621 tcgagggcct gaatcagcag gtccaactgt gtggcaagac gacgcgcagt gaattggagt
     1681 ccacgtactt catccatggg gctccttgag gcgagactgc tgactgcgac cgatcatccg
     1741 tcacttgacg tgttcgccgc cgacccaagc cggcgtgccg tctgggtgcc gaagacgcat
     1801 gcgttgctga ccgtctgcat tcgccagctc ggcggccact aatacgtgtc tgccgtctac
     1861 cagagccgga ctacagacgg ccgtcacgag tcgaccttta ttcacgtcaa aacgttcgtg
     1921 atattcattc atgtaccaag tcggtcccag atgcacccgg actggaccac gttcggtttc
     1981 tacttccatc tgcataaact ccaccccatc tttcaatctg acagcggtgg tatccagtat
     2041 gatgcctttg acgactcgaa tctcatcctc tgagaagagt tttgccgagg cttctgctga
     2101 ttcgtagggt accttgtcgg atacgggcag agcctgtgtc ccatgaatcg tggcgaagag
     2161 gagcatttct ggcagcatgc cgagtctcct ttgtgaatgt atgagttgac cgtagcaccc
     2221 agtcggcctg cagcaaacta ggagtgtccc gcgcatgctg ccctgcacca tcgaaatagg
     2281 aaaaggggag agaggctcgg ctggatcctg ccggcatcac aggttagctg gagtgggggg
     2341 atccgccgcg gagcggaaag gatgggagga gctactagtg tttgtccttc cggccgggtg
     2401 tgaaaggaat aatgctaatt ccgcgggcgt ccacatacac cttcttcccc ggctgctgct
     2461 tgatggccgg gaggatgtgc tctcccatct ggccttgcag cgcgatgagc gtggtatcgt
     2521 caaaatagtt cctggagaat tccagctctg tgtgacagcg cccatcgcta aacagaaagc
     2581 gtttggggac gactgtcagc ctgatctcct gatagccggc tgattccagt gccgcaatga
     2641 tggcctcgtt cttcgtcagg tctggcatcg tgcctccctc tctccgtcta tctctgattc
     2701 cggcacgcgt tgatctgctg atgcgtcggt cgtcgagcat gtgagcgcgg gcttggactg
     2761 catcgtggag gccgtcgttc acatgggatg gattgagtga gaggaagcca aaatggaaga
     2821 tcgggaatca gggatctgca cagcaacgat agtgcgggcc gccgccttca gtttgtcgaa
     2881 ttccgcgaac agcgtgtctt cctctcggcg tatgcgtgtt tgcaacagaa agaggatgtt
     2941 gccaatgtcc tgtgtcgtgt gatggtgtgt gccactgatg tggaactggt caaaaaagcc
     3001 aatcacttcc tttgagacgc ctgccatgtc tttctcaagg aattgcaacg tatacttcaa
     3061 ttccgtattc ttttcggcgg cttcgaataa gacgggatac aggagcgtgt cttctaattt
     3121 gaagtgcgcc aaaaggtgta ttttcgccgc tctcagtttc cgttgcgctt cgactttttc
     3181 cacgccgatc cactgcgcgg cttccaataa gttcgagatg aacaaatgtt gcagtctcag
     3241 tgtcgaggtt aagtttgtca tgagacttct tgctccttca ttcggtctac ggctcagctg
     3301 acacaggacc cagtcggaag tcgtcaccaa tcggtgatgc agacgtcgcg gtcctgacca
     3361 tcatccacag acgtcatggc tcgcccgctg gttcacgatg atgccggagg ataccggcgc
     3421 gacgagcctg cggtcgaacg tcatcatctt gtaaaagtag cagtgatttt tgaaatgtct
     3481 gtaggttgga ctcgggtagg gagcctgggg aaatccatag gagtgtaggg tttcagctgt
     3541 cagcgtt
//
LOCUS       DAOQPD010000156         3535 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_18632_length_3535_cov_18.511207, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000156 DAOQPD010000000
VERSION     DAOQPD010000156.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 3535)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3535)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3535
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_18632_length_3535_cov_18.511207"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..>3535)
                     /locus_tag="PK063_18545"
     CDS             complement(<1..>3535)
                     /locus_tag="PK063_18545"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HMZ99103.1"
                     /translation="VTFNERWATMLGYQLHELEPNVGTWEQLVHPDDLPAVKERVSAH
                     LRGETPLYSTEHRLKTKSGTWCWVFDSGRVVERDASGNPVRAAGIHLDISARKELEAA
                     QALAQRDLQVKQQALDEAQTLAHLGFWEWDIVTGDEQWSNEQCRIFGFEPGTVKPTYA
                     TFLSALHQDDKSRVQQAIDAAITYDFPYNIDCRIHRPSGEVRHINCRGTVRRKPDGSP
                     LAMTGTVQDITAHKHAELAWRESEARMRSIFESAIEGIVVIDEKGRIESVNAALLQLL
                     GYEAHELIGQNISLIMPEPYRANHSHYLANYLVTGKRVIIGSGREVTAVRKDGTLIDI
                     HVSVSEMQIGPSKKYTGMIRDISERKRMEETIRESEARFRQLAESIDAVFWLTTPDKS
                     EVLYVSPAFETIWECPRDILRTNPLFWLEHIHPEDQKRVSVAAACQAHLPYDEEYRII
                     TATGRERWIRDRSFVIKNEAGQTYRIAGIAQDITESKQLEAQLRASELRHRSLVELSP
                     HAIFVNCDDKIVFANQACVKLFGAFASSQIVGKRVIEFIHPDSQTIAQERIARLRSAN
                     GSVPPIEERFVALDGSILDVEVAAATIRFEEKPAIQVILTDIRARKELERALVATNLQ
                     LEAILASATKVSIIAINTAGIITTFNAGAEEMLGYSAEEMIGQPMLTALHLPEEIDKH
                     TRDMSELYGASFQRLEALTQQARLGGFDEQEWTYRRKDAQRLTVLVTITALKNTDGVV
                     TGFLAIGKDITQRKEAEAALTEAARELARNNVELAQARDEALQAAQAKADFLATMSHE
                     IRTPMNAIIGMTGLLLDTALTEEQHDFAETVRRSSDALLTIVNDILDFSKIEAGKLNF
                     EEIAFDLRLAVEDTIELMAEQAQSKGLELISLVDAAVPTGVLGDPGRLRQILVNLVSN
                     AVKFTTTGEVFVHVTRETGESPNHLRFAITDTGIGISDEAQKKLFHAFVQADSSTTRR
                     FGGTGLGLAICQRLVQQMHGRIGIDSRPGEGSTFWFTVALPEAALSPTSFALSWDRLS
                     GRRILVVDPNNRMRKVLQEDLAAKGLQCSSASNAGEALDLAQAAAAMQKPFDLALIEL
                     HLPDKDGFETAALLKQNSTTSGMRLVILTTVGRRGDGTIARQLGIDAYLTKPLRQTQL
                     LECFCQLLDVAPPGVASDTASTGTPPLITRHT"
BASE COUNT          655 a          994 c         1069 g          817 t
ORIGIN      
        1 ggtatgccgg gtaatcagcg gcggtgtgcc ggtggaagcc gtgtctgacg cgacgcccgg
       61 cggagcgaca tccagcagct gacaaaagca ttcgagcaac tgtgtttgcc gcagcggttt
      121 ggtgagatag gcatcgatgc cgagctgccg cgcgatagtt ccatctcccc gccggccgac
      181 ggtggtcaaa atcaccaggc gcatgccgct ggttgtggaa ttctgcttca gtaacgcggc
      241 cgtctcaaaa ccgtctttgt cgggcaggtg caactcgatc aaggccagat cgaagggctt
      301 ctgcatggct gcagccgcct gcgccaggtc caaggcctct cccgcattgc tggcactact
      361 gcactgcaga cctttggccg ccaggtcctc ttgcagcacc ttcctcatcc tgttgttcgg
      421 atccacgacg agaatgcgcc gcccgctgag ccgatcccat gaaagagcga aagacgtagg
      481 gctaagagct gcttcgggta gtgcgacggt gaaccagaag gtgctccctt cgccgggccg
      541 gctgtcgatg ccgatgcgtc catgcatttg ctggacgagg cgttggcaaa tggcgagtcc
      601 gagaccggtt cctccgaatc ggcgggtcgt cgaactgtcg gcctggacga aagcgtggaa
      661 cagttttttc tgcgcctcat ccgagatgcc gatgcctgta tccgtaatag cgaaacgcag
      721 gtggttcggg ctttctcccg tctctcgagt gacgtggaca aacacctcgc ccgtcgtggt
      781 gaacttcacg gcattgctga cgaggttgac gagaatttgt cggagccggc cgggatcgcc
      841 caggacgccg gtggggacgg cggcatcaac caggctgatc aactcgaggc ccttgctctg
      901 cgcttgttcg gccatcaact caattgtgtc ttcgacggcc aatcgaagat caaaggcgat
      961 ttcttcaaaa ttgagtttcc cggcctcgat tttcgagaag tcgagaatat cgttgacgat
     1021 ggtcagcagc gcatcactcg agcggcggac ggtctcggcg aagtcgtgtt gttcttcggt
     1081 gagggcagta tccagcagaa gtcctgtcat cccgatgatc gcattcatcg gggttctgat
     1141 ttcatggctc atggtggcga ggaagtcggc tttcgcctgg gccgcttgca gagcctcatc
     1201 tctcgcctgg gcgagttcca cgttattccg tgccagctcg cgggcggcct cagtcagggc
     1261 ggcctccgct tccttccgtt gggtgatgtc ttttccgatg gccaggaatc cggtcacgac
     1321 accgtcagtg tttttaaggg ccgtgatggt gaccagtacc gtgaggcgtt gcgcatcttt
     1381 tcgccgatag gtccattcct gctcgtcgaa cccgcccagt cgagcctgct gggtcaacgc
     1441 ttccaatctc tggaaggaag cgccgtatag ctcgctcatg tcgcgggtat gcttgtcgat
     1501 ttcttccggt agatgcaggg ccgtgagcat gggctgcccg atcatctcct cagcggaata
     1561 tccgagcatc tcttccgcgc ccgcattgaa ggttgtgatg atgccagcag tgttgatcgc
     1621 gatgatggac actttggtgg cgctggcaag aatcgcttcc agttggagat tggtggcaac
     1681 caaggcccgc tcgagctctt tacgggcacg aatatcggtc aaaatgacct ggatggccgg
     1741 cttttcttca aaccggatgg tggcggcagc cacttccaca tcgaggatgg aaccatcaag
     1801 cgccacgaag cgttcctcta tcgggggtac gctgccgttc gccgaccgga gacgagcgat
     1861 tcgttcttgg gcaatcgtct gtgagtccgg atggatgaat tcgattacgc gcttccccac
     1921 gatctgcgaa gaagcaaatg ccccgaagag tttcacgcag gcctggttgg caaacacgat
     1981 cttatcgtca cagttgacga aaatggcatg gggcgacagt tccaccagag atctgtgccg
     2041 tagttcactg gcgcgcagtt gtgcctccag ctgtttggat tcggtgatgt cctgcgcgat
     2101 gcccgcgatg cgataggtct gtcctgcttc gtttttaatg acgaagctgc ggtccctgat
     2161 ccagcgttca cgtcccgtag ccgtgatgat ccgatattcc tcgtcatagg gcagatgcgc
     2221 ctgacaggct gccgcgaccg atacacgttt ttggtcttcc gggtggatgt gctcgagcca
     2281 gaagagggga ttggtacgga gaatgtcgcg cggacattcc cagatggttt cgaacgcagg
     2341 gctgacgtac agcacctcgc tcttgtccgg cgtggtgagc cagaagaccg catcgatcga
     2401 ttccgccaat tgccggaagc gcgcttcgct ctcacggatg gtttcttcca tccgcttgcg
     2461 ctcggagata tcccgaatca ttcccgtata ttttttcgag gggccgatct gcatttcact
     2521 gacggacaca tgaatgtcga tgagagtgcc gtcttttcga accgcggtca cctcgcggcc
     2581 gctgccgatg atcacccgtt tccccgtgac caggtaattg gcaagatagt gcgagtggtt
     2641 ggcgcgatag ggctcaggca tgatcagcga aatgttctgg ccgatcaatt catgcgcctc
     2701 atatcccaac agctgtagca gggccgcatt gacgctttcg atgcggccct tttcatcgat
     2761 gacgacgata ccctctatcg cgctttcgaa gattgagcgc atgcgggctt cgctctcacg
     2821 ccatgctaat tcggcgtgtt tgtgggcagt aatgtcttgc accgttccgg tcatggcgag
     2881 gggagaaccg tcgggttttc ggcggacggt tccacgacag ttgatgtggc gcacttcgcc
     2941 gctcggccgg tgaatccgac agtcgatgtt ataggggaag tcgtaggtga tcgccgcatc
     3001 aattgcctgt tggacgcggc tcttgtcgtc ctggtgcagg gcggagagaa acgtggcata
     3061 ggtcggcttg acggtccctg gctcaaagcc gaatatgcgg cattgctcgt tcgaccattg
     3121 ttcgtccccc gtgacaatgt cccactccca gaagccgaga tgagccaatg tttgcgcctc
     3181 atccagcgcc tgttgtttga cttggagatc tcgctgggcg agagcctggg ctgcttccaa
     3241 ttccttgcgc gcggaaatat cgagatggat gcccgcggct cggacgggat tgcctgaggc
     3301 atcgcgctca accacacggc cgctatcaaa gacccaacac caggttccgg acttggtctt
     3361 caggcgatgt tcagtggaat agaggggcgt ttcgccgcga agatgcgccg agaccctctc
     3421 cttcacagcg ggtaggtcgt ccggatggac gagctgctcc caggtgccaa cgtttggttc
     3481 gagttcatgc agttggtagc cgagcatggt tgcccagcgt tcgttgaacg tgacc
//
LOCUS       DAOQPD010000157         3293 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_21122_length_3293_cov_22.204138, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000157 DAOQPD010000000
VERSION     DAOQPD010000157.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 3293)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3293)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3293
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_21122_length_3293_cov_22.204138"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..957
                     /locus_tag="PK063_18550"
     CDS             <1..957
                     /locus_tag="PK063_18550"
                     /inference="COORDINATES: protein motif:HMM:NF015948.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HMZ99104.1"
                     /translation="GPLVLPKPIPVNPFMRGGRALVCIVYGTDPARMLGRALELLGGI
                     DRMGVRGTRVLLKPNVLNDQPPPSTTNPLVVKAMANIVRANGAAEVVVADGSGIIRLP
                     TSANLTSTGMRTAAESAGARVLALEDEPWVRLEPPNAKAIGHFYFSKPVYDADVVINM
                     PVIKTHRFAEFSCSLKNFVGAVHPRYRPSVTFWSGDWHERIAEINLAVHPVLTVADGT
                     TTMIDGGPTSGTPSRTDLLICSGDRVAVDLTALALLRSFGKSSKLQGRRIVDQRQIRR
                     AADLGLGVGSGRGIELVTEAVDPAPPAFLRLVEHIRQELLES"
     gene            complement(961..1518)
                     /locus_tag="PK063_18555"
     CDS             complement(961..1518)
                     /locus_tag="PK063_18555"
                     /inference="COORDINATES: protein motif:HMM:NF015871.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpH family outer membrane protein"
                     /protein_id="HMZ99105.1"
                     /translation="MGVKWHGAGRRAVVVGALVAATLGLFSTSPAAEFKMGVVDPQVI
                     LEKSKAGKRALDGLREYVATRQKLLSRDEEELRNTEKQLKEQASKLTDAEKKDKETSF
                     RSKIQDYQKRAQEFNQELQGKQKELVDEYMKKIAVATQAVADKGGYQLVLDKGSEQTV
                     KIVIFNKDTIDLTEQVIKEFDRTNK"
     gene            1719..2120
                     /locus_tag="PK063_18560"
     CDS             1719..2120
                     /locus_tag="PK063_18560"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99106.1"
                     /translation="MSSEQEQAHRLFIRALQHEAISCERAGCPGPVETLDQSQTRDRV
                     KTFDMTCERCGWHTSVTGREQLTPLWDNASLELMADEHLLHQQPVCPYDDTPVVFISM
                     PNPRRKAKYRVACFYCGRQIEMDWPPPESKR"
     gene            complement(2151..>3293)
                     /locus_tag="PK063_18565"
     CDS             complement(2151..>3293)
                     /locus_tag="PK063_18565"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: protein motif:HMM:NF014069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD-GYP domain-containing protein"
                     /protein_id="HMZ99107.1"
                     /translation="VSLDPEKHTLADLQEALQTAGVNGIELEEPRALQLQQSNDADAM
                     AGEGGTRVGSSAGGQENSKEKRKAIAKGRYAKAASALGDLTKSTRAGGTVSFKQAKRA
                     IQNIVELMMQDESTLLGLTNLRCHDQYTHNHSVNVSLLAMALGNRAGYPKVDLADLGL
                     SALFHDVGKCAISLDVLNKPGEFTQDEWAIMRSHPIEGVFTLVKARGINNVPARMASA
                     SFEHHMNYDFSGYPKLKVPWSQTVASRIITIADCYDAMTSSRVYRREPMSPANVLKFM
                     FGKSGQSFDPVLLKLFVNCVGIIPIGSLVRLDSGPLAVVIKPAQDKANAERPMVRVIT
                     DTEGTPIEDGPELDLAAQDDTGTYTHNILQLVDNAEYHFDTGRYFV"
BASE COUNT          619 a          942 c          983 g          749 t
ORIGIN      
        1 gggccgttgg tgttgccgaa gcccattcct gtcaatccat tcatgcgggg agggcgcgcc
       61 ctcgtctgca ttgtgtacgg cacagatccg gcgcgaatgc ttgggcgtgc gcttgaactt
      121 cttggtggaa tcgatcggat gggggttcgc ggcacccgtg tcctgctcaa acctaatgtg
      181 ctgaacgatc agccgccgcc ctcgacgacc aatccgctgg tggtgaaggc tatggctaat
      241 atagtcagag cgaatggagc ggcagaagtg gtggtggccg acgggtccgg aatcatccgc
      301 ctgcccacct ctgccaattt aaccagcacc ggtatgcgga cggcagcgga atcagccggc
      361 gcgagggtgc tggcgcttga agatgagcct tgggtgcggc tcgaaccgcc caatgccaag
      421 gccattggcc atttctattt ctcgaaaccg gtgtatgacg ctgatgtcgt gattaatatg
      481 ccggtcatca agacgcatcg ctttgccgag ttctcctgta gtctcaaaaa tttcgtgggc
      541 gcggtccatc cacggtaccg tccctcggtc acattctgga gcggggattg gcatgaacgc
      601 attgctgaga tcaatctcgc ggtacatccc gtactgaccg tggccgatgg gaccacgacc
      661 atgatcgatg gcggtccgac atcaggtacc ccgtccagga cggatcttct gatctgcagt
      721 ggagaccgag ttgcggtgga tctgacggcg cttgcgctgc tacggtcgtt cggcaagtcg
      781 tcgaaactgc agggcaggcg gatcgttgat caacggcaga tccgacgcgc ggcggatttg
      841 ggcttaggag tcggatcagg acgcgggatc gaacttgtta cggaggcggt ggacccggct
      901 ccaccagcgt ttcttcggct ggtggagcac attcggcagg aattactgga gtcctgaccg
      961 ttacttgttg gtgcggtcga attccttgat gacttgttcg gttaaatcga tcgtgtcctt
     1021 attgaagatc acgattttca ccgtttgctc gctaccctta tccaacacca attgatagcc
     1081 gcccttgtcg gcaacggcct gggtggctac ggcgattttt ttcatgtact cgtcgacgag
     1141 ttccttctgc ttgccctgca gttcctggtt aaactcctgc gcgcgctttt gataatcctg
     1201 gatcttgctc cggaacgacg tttctttgtc cttcttttcg gcgtcggtca gcttggaggc
     1261 ctgctctttg agctgctttt ccgtattgcg caactcttcc tcatcccggg acaacagttt
     1321 ctgacgtgtt gccacatact cccgcagtcc gtccagcgct cgcttgccgg ccttgctctt
     1381 ctcgagaatc acctgaggat cgacgacccc catcttgaac tctgccgccg gactcgttga
     1441 aaacaagccg agggtcgctg cgacaagcgc cccgaccacg accgcgcgcc ggcctgctcc
     1501 gtgccacttc acacccatct cgggactcct ttcgcgggaa taatgtcgtg ctacaaacct
     1561 cgggaggata gctgcctgcc cgtatcgtgt caaggaggga gcggcggggt gagtggggga
     1621 tttgacaggc ctgggaccgg tggctataag ccaacgcagg cactcatcgt ctgcacatcc
     1681 ggccgggtcc cagggccgga tgggaaagga aatctatcat gtcttccgag caagagcagg
     1741 cccatcgctt atttatccgg gcgctacaac atgaggcgat tagctgcgag cgcgccggat
     1801 gtccggggcc ggtagagacc ctcgaccagt cgcaaacacg cgatcgggtc aagacgtttg
     1861 atatgacctg cgaacgatgc gggtggcaca ccagcgtgac cgggcgcgaa cagctcacgc
     1921 cgctctggga caatgcctca ttggaactga tggcagatga acatctgctg catcaacagc
     1981 ccgtatgtcc atatgacgac acgccggtcg tgtttatctc catgccgaat ccgcgccgga
     2041 aggcgaagta ccgggtggcg tgtttttatt gtggccgaca aattgaaatg gattggccac
     2101 cgcctgaaag caaacggtag caacgcggcc tgaccggagg tgccggcggg ttagacgaag
     2161 tagcgaccgg tgtcgaagtg gtactcggcg ttgtcgacga gctggagaat gttgtgcgtg
     2221 taggttccgg tgtcatcctg cgcggccagg tcaagctcgg gaccatcctc gatcggcgtt
     2281 ccctctgtgt ccgtaatcac tcgcaccatc ggacgttccg cgttggcttt gtcctgagcg
     2341 ggcttgatca caaccgccag gggaccggag tcgaggcgca cgaggctccc gatgggaatg
     2401 atgcccacgc agttcacgaa cagtttgagc agcacggggt cgaacgattg cccgcttttc
     2461 ccgaacatga atttgagcac gtttgctggg gacatcggct cccggcggta tacgcgcgat
     2521 gacgtcatcg catcgtagca gtcggcgatc gtaatgatgc gactggcgac ggtttgactc
     2581 cagggcacct tgagtttggg gtagcccgaa aaatcatagt tcatatgatg ttcgaaggag
     2641 gccgaggcca tgcgcgcggg cacgttgttg atgccccgag ccttcacgag ggtaaacacg
     2701 ccttcaatcg ggtgcgagcg catgatggcc cattcgtcct gcgtgaactc gccgggtttg
     2761 ttcaagacat ccagagaaat ggcacatttc cctacgtcgt gaaacaacgc cgacaaaccg
     2821 agatcggcca ggtctacctt cgggtacccg gctcgattgc ccagggccat cgccaggagt
     2881 gacacgttca cggaatggtt atgggtatac tgatcgtggc agcgaagatt ggtcagtccc
     2941 aggagtgtgg attcatcctg catcatcagt tcgacgatgt tctgaatcgc gcgtttcgcc
     3001 tgtttgaagc taaccgtccc tccagcgcgc gtactcttcg tcaggtcgcc gagcgccgag
     3061 gccgccttcg cataacgacc tttggcgatg gccttcctct tctccttcga attttcctgg
     3121 ccgccggctg aggatcctac ccgcgtccct ccttcaccgg ccattgcgtc ggcgtcgttc
     3181 gattgctgga gttgaagtgc tcgtggttct tccagttcga taccgttgac gcccgccgtc
     3241 tgcagggctt cctgcaaatc ggccagcgta tgtttctccg gatcgagact gac
//
LOCUS       DAOQPD010000158         3286 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_21201_length_3286_cov_26.980192, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000158 DAOQPD010000000
VERSION     DAOQPD010000158.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 3286)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3286)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3286
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_21201_length_3286_cov_26.980192"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            441..578
                     /locus_tag="PK063_18570"
     CDS             441..578
                     /locus_tag="PK063_18570"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99108.1"
                     /translation="MNKFTMVLFIGLLLAGVLALSLWFGTPHQDPAWLAATDRELAQV
                     D"
     gene            complement(1260..1934)
                     /locus_tag="PK063_18575"
     CDS             complement(1260..1934)
                     /locus_tag="PK063_18575"
                     /inference="COORDINATES: protein motif:HMM:NF017319.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HMZ99109.1"
                     /translation="MTLIDRTMREGALTSRFARLLVVVLLAALTSLIFLVPAKAAESE
                     LTPTETVSDMINELFSILKEHQGPELFHERRREIERVIRRDVHYEEMAKRSMGPSWVR
                     MDDQARTDYVDLFVHLLRDALTNRMVQSQDEQIIYLSERRESTCAEVRTRLVGSKLDT
                     TLDFRLIHDDGHWLVYDAIMDGTGLVGTYRVQFASIIRDESLAELLNKLKANTLLVKL
                     FDAHGS"
     gene            2848..>3286
                     /locus_tag="PK063_18580"
     CDS             2848..>3286
                     /locus_tag="PK063_18580"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99110.1"
                     /translation="MRHLARVLSLSTILVTLCVGMTSCRAHSDGYWTKPERSQALTNE
                     VYSADSAECQMMVESNSLEETPTYKAKLFAHCMQAKGYTWIVETQKSYPVKEAAIQPA
                     LHCSNGRRIVDAFGFQKCVPDGTKDGGMLQEARRAIPAPVLSHD"
BASE COUNT          773 a          857 c          888 g          768 t
ORIGIN      
        1 ccagaacgtc tcttgatccg gccagacttt cctacgcgac acgacaggcc caagcggccg
       61 gaatggcact gtaatcaatg tgggcggacc tttgcaccgg attacttcga cgaactgggg
      121 tagcgcgatg ttctagtcat cccatagttg ggcggtactt gaaaaaacct ttggctgaag
      181 tgatgcaccg tctcgcacgg aagacggata aacaagacgt tcaacggcaa tggcagcgag
      241 ctaggagtag aacaatcacg aactcaaaga gctggtaacc agcgcccaca cccttttgga
      301 tgccggggaa ctcctcgcgt cccgtacgac acacacagtg ccctcccact gtaggtcttc
      361 gaccacccct ctatagaata tgcctgcgtt ggtcagccac cctaaagtgg cggcatgcat
      421 gcacttaaac ggaggggcgg atgaacaaat tcacgatggt gttgttcata gggttactgc
      481 tggccggtgt tctggcattg tcgctgtggt ttggtacgcc gcatcaagat ccagcgtggc
      541 tagccgccac agaccgggag ttggctcaag tcgattgatg ggcttgggat gtgaggaggg
      601 cctgcaatca ctcaggccct tgtacagcta gattcatgcc tggtgggatt gggctcggat
      661 ccccagtctt ttcagttgct tggtaatgtc tgggatagtg cgcgtgtcga tgcaattggg
      721 cctcggacat tgcgattctg tgactgcaaa ggcggcatac ataagcccct gtcagataca
      781 caccgcctac actctccaat tgataatcgt gctcgcattg tgagtcgatc aatcccatgg
      841 caaggagttc tgccacctca tccgcggcct ctttggtagg taacggatag tcccattcac
      901 ctgtcacagg gtggcctttc tcttccgtct cggcggagcg tatgaccaag gcgtgtggga
      961 cccattggcc cccgctccgg taagacatca agcgtatggt gcaatccttg tacacaacat
     1021 tggattcgtt gctggatgcg tgattcattg ttccaacctt caatccatcg tcaatagtga
     1081 aaatccaagc ggctcaggag tgctgtcaca ctgttcgcct tcagaggaaa ctgggagggc
     1141 cctagctgac tatacgaact tcagggcggc ggacctgctg tcgggatagc tcaactgtaa
     1201 cggttgcacc agatctcatg cccggttttg gtgcaggggg cgacaaatgc atggttcagt
     1261 catgatccgt gtgcatcaaa cagttttacc agcagtgtgt ttgccttgag tttattcagc
     1321 aattctgcca atgactcgtc gcgaatgatg ctcgcaaact gtacacgata ggttccgaca
     1381 agaccggtcc cgtccatgat ggcgtcgtac accagccagt gtccgtcgtc atgtataagt
     1441 cgaaagtcga gagtcgtgtc cagcttgctg ccaacaagtc gtgtcctaac ctcggcacat
     1501 gtcgactcac gtctctcgga gaggtagatg atttgttcgt cttgagactg aaccatccta
     1561 tttgtcagcg catcccggag tagatggaca aagaggtcca catagtctgt gcgggcttga
     1621 tcgtccatcc gcacccatga aggtcccatc gaacgcttgg ccatctcctc gtaatggacg
     1681 tcgcgtcgaa tcactcgttc aatttcacgc cggcgttcgt ggaaaagctc agggccttga
     1741 tgctctttca atatggaaaa cagttcattg atcatatcgg agacagtttc agtcggcgtc
     1801 agctccgact ccgctgcctt agcaggtaca aggaagatta ggctggtcag tgctgcgagt
     1861 agcaccacta ccaggagacg ggcaaagcgg gaggtaagcg ctccttccct cattgttcga
     1921 tcgatgagcg tcatcccacg gttcatttca actcaccagc aacgatccgg tcctacgcta
     1981 tttgcagatc agacttcttt ttgagggaag agaagcagta gcacgcgtaa cacatacatg
     2041 atgctgagga cggaaaagcc gccatatgca aggtagatca acaagctcat ccattcgtcc
     2101 atgaagcccc cgaatgcccg tccttgtcat ttctattaga tcgggtgaaa agatacagga
     2161 attttcgccc cggtactgct aggaagaccc cttgcggagg atatcgctat cgggtgacgc
     2221 gtcgaacgct acaggagatg caggagatga atgataatcg aaggggctga agggaagatt
     2281 attgctatgc cgcgcgacga aagtcagcgg tttcagcatt ttttctgttc tccgtatcgt
     2341 catcgagtgt agccgccgca ttaggtttcg tgcagcggcg tatcatctgg gtgatgacga
     2401 ttgccaggag aatgtaattc aggatgccca ggaccagact tatacagatg acctcttcag
     2461 aaatcaccga agaagtgtag cgcaaggaga gcgatccgca agtcgccagg cagagagccg
     2521 caataggaaa agactatgcc acttgcgctg gcgcagtttg tgtccgttca gtgcgagtgc
     2581 gatttattct ttgtcaatga tagcccgccg ctccaatcct accgcctcga gtatgcgact
     2641 cgagcgaagt gtaggagaag gtgaagatgt agggaggtca gcaagaacca gcgcagcagt
     2701 ccactggcgc gggcagttca tctcccgtgg gacttaattc tcgtcacgtg aagtctatct
     2761 cagcgtttat ctcagcgggt ttccagccag ggccttacct agcgtgcgat cggctctatg
     2821 aactctatag tgaagggtgg aggtcgcatg cgccatttag cacgggttct ctcactcagt
     2881 acgatccttg ttaccctgtg tgtgggtatg acctcttgcc gagcccactc agacggttac
     2941 tggaccaaac ctgaacggtc gcaggctttg accaacgagg tctattcagc agattcagca
     3001 gaatgccaga tgatggttga aagcaacagc ctcgaagaga caccaacgta taaagcaaag
     3061 ctcttcgccc actgcatgca ggccaaaggg tatacgtgga tcgtagagac acagaagtcg
     3121 tatcccgtaa aagaagccgc catacaaccc gctcttcact gctctaacgg gcgacgtatc
     3181 gtcgatgcat ttggtttcca gaaatgcgta cctgacggga ccaaagacgg aggcatgttg
     3241 caagaggcga gacgtgcgat tcctgctcct gtgctttctc acgatc
//
LOCUS       DAOQPD010000159         3283 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_21237_length_3283_cov_20.779740, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000159 DAOQPD010000000
VERSION     DAOQPD010000159.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 3283)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3283)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3283
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_21237_length_3283_cov_20.779740"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            24..455
                     /gene="rplM"
                     /locus_tag="PK063_18585"
     CDS             24..455
                     /gene="rplM"
                     /locus_tag="PK063_18585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HMZ99111.1"
                     /translation="MTKTYLEKPANVQRKWYLVDAEGKTLGRLAAKVATLLRGKHKPT
                     FTPHVDTGDHVVIVNAEKVVLTGNKMENKTYSTHSGFPGGLKTLTAEHVHRKDPTKLL
                     TKAIEGMLPKNPLGNHMAKKLRVYAGATHPHQAQKLESLSL"
     gene            498..890
                     /gene="rpsI"
                     /locus_tag="PK063_18590"
     CDS             498..890
                     /gene="rpsI"
                     /locus_tag="PK063_18590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HMZ99112.1"
                     /translation="MAAMTQYATGKRKSAIARAWVTAAAGDIVINEKPLEKAFPRPTL
                     RNVIQFPFELAGVAGKYSVRATVYGGGPAGQAGALRHAISKALVIMSAAFRGPIKKEG
                     LLTRDSRVKERKKYGQKGARKRFQYSKR"
     gene            997..2070
                     /gene="argC"
                     /locus_tag="PK063_18595"
     CDS             997..2070
                     /gene="argC"
                     /locus_tag="PK063_18595"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003942 -
                     N-acetyl-gamma-glutamyl-phosphate reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HMZ99113.1"
                     /translation="MTSVRVAVAGASGYTGAELVRLLSQHPHVQLTAVTSEKSAGMAI
                     SAVYPHLQGIVQLPFEALAPEALAERADVLFLALPHTKSMGPVASCMKAGKRVIDLSA
                     DFRLKNPATYETWYQTAHAQPQLIKDAVYGLPELHRAAIAQARLVASPGCYPTAAILQ
                     LAPLIAHGLVSPDSIVIDAKSGISGAGRSPALPYHFPEAHESLEPYKIGQHRHIPEIE
                     QELTGLAGSKGRAAEAGQGPVTVAFTPHLVPMNRGILSTAYARMTNQPDVAELRNLYR
                     EFYKGERFVRLLEGAMPNPRHVRGANYCDIAVQTDRRAGWVVTVSAIDNLIKGAAGQA
                     IQAMNLMLGYPEETGLIAPGVYP"
     gene            2128..>3283
                     /gene="argJ"
                     /locus_tag="PK063_18600"
     CDS             2128..>3283
                     /gene="argJ"
                     /locus_tag="PK063_18600"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: protein motif:HMM:TIGR00120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004358 - glutamate N-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HMZ99114.1"
                     /translation="MKTISGGVTAPIGFRAAGVYSGIKKKKKKQLDLALLVSDREGPV
                     AGVFTKNQVVAAPVILDRLHLKQGVGRAFLVNSGNANACTGPEGMQAAKEMAKLAATA
                     LNCAPQTIFVGSTGVIGQPLPIDCIRKALPALSARITRRGGAEAAAAIMTTDLKPKHV
                     AVRALLGGKMVTVGGMAKGSGMIHPNMATMLGYLTTDAAIGQRALQAALRQAVDQSFN
                     CITVDGDTSTNDTVLCLANGMADNRPITPGSADFTRFCAMLETVCRTLALKICWDGEG
                     VTKVVRVEVKGAQSTKAAKQVAQTVATSNLVKTALFGGDANWGRVMAALGRAGVPIDP
                     SRISLQFGGVPMVRKGQGLGRAAERQLTKVFKAKEFTILIDLAQGKAGAHM"
BASE COUNT          770 a         1002 c          930 g          581 t
ORIGIN      
        1 tcgtgcagga gtagatggag accatgacaa aaacgtatct cgagaaaccc gctaacgtgc
       61 aacgaaaatg gtacctcgtg gacgccgagg gcaagaccct tggccgcctt gcggcgaaag
      121 tcgccacctt gctgcgaggg aaacataagc cgacgtttac cccccatgtc gataccggag
      181 accatgtcgt cattgtgaat gcggagaagg tcgtactcac cggcaacaaa atggagaata
      241 agacctattc gactcacagc gggtttcctg gcggcttgaa gaccctcact gccgagcatg
      301 tccacagaaa agaccctacc aagctgttga cgaaagccat cgagggcatg ttgccgaaaa
      361 atccacttgg taaccacatg gcgaaaaagt tgcgcgtgta tgccggcgcg acccatccgc
      421 accaagcaca aaaactggaa tcactctcgt tgtgattttt attctttgta ttcgatcagt
      481 gaaggagacc gcctgatatg gccgcaatga cgcagtacgc aaccggaaaa agaaaaagcg
      541 cgatcgcgcg cgcatgggtc accgcagccg ctggtgacat tgtcatcaac gagaagccgc
      601 tcgaaaaagc gtttcctcgc cccacgctgc ggaatgtgat tcaatttccg ttcgagttag
      661 ccggagtggc aggtaaatat tccgtccgcg ccaccgtcta cggtggtggc cccgcaggcc
      721 aggccggagc tctccgccac gccatctcga aagcgctggt catcatgagc gcggcgttcc
      781 gtggtcccat caagaaggaa ggccttctga ctcgcgattc tcgcgtgaaa gaacgtaaga
      841 agtacggcca gaagggcgcc agaaagcgct tccaatactc gaagcggtaa cgaacgactg
      901 gagcgacagg gttcaaaagg gaaggctccg cagccttccc ttttttattg gctcgctgca
      961 ggtgggccac aatttgtcac gggccgggag gcgaagatga cgtcggtacg agtagcggta
     1021 gcaggggcca gcggatatac cggagcagaa ctagtgcggc tcctctctca acatccccac
     1081 gtacaactca cagcggtcac ctcggaaaag tcagcaggca tggccatctc tgccgtgtat
     1141 cctcacctgc agggaatcgt gcaactccca ttcgaagcgt tggcaccgga agcgttggcg
     1201 gagcgggccg atgtcctgtt tctggcactc ccccacacca aatcgatggg tcccgtggca
     1261 agctgcatga aggccggcaa gcgtgtcatc gatttgagcg ccgacttccg gctgaaaaat
     1321 cccgctacgt atgaaacctg gtaccaaacc gcacatgcac aaccccagtt aatcaaggat
     1381 gccgtgtacg ggctgccgga acttcaccgc gctgccattg cacaggcccg actcgtagcc
     1441 tcacctggct gttaccccac ggctgcgatt ctccaactcg cacccttgat cgcccatgga
     1501 ttggtctcgc ctgacagcat tgtgattgac gcaaaatccg gcatctcggg cgcaggaaga
     1561 agtcccgccc tcccctacca ctttcccgaa gcccacgagt cgctggagcc ctacaagatc
     1621 gggcagcatc gacacatccc tgaaatcgag caggaactca ccggattagc cggcagcaag
     1681 ggacgtgcgg ctgaggctgg acagggccct gtgactgtgg ccttcactcc acacctcgtc
     1741 cccatgaatc gaggcatcct cagcaccgcc tatgcacgaa tgacgaacca gcccgatgtt
     1801 gccgagttac ggaatctcta tcgggagttt tacaagggcg aacgatttgt gcgcctgctc
     1861 gaaggcgcca tgccgaatcc tcgccacgtg cgaggagcca actattgcga catcgccgta
     1921 caaaccgatc gacgcgccgg ttgggtcgtg accgtgtcgg ccattgataa cctgatcaaa
     1981 ggggcagccg gccaggccat tcaggccatg aatctgatgc tgggttaccc ggaagaaacc
     2041 ggcctcatag ctccgggcgt ctacccctag cgtgcacttg catgggcccg tcatagcgag
     2101 tcaccttcac atcacatagg aagagcgatg aagacaattt caggaggcgt caccgcgccc
     2161 atcggttttc gagccgccgg agtctacagc ggcatcaaaa agaaaaagaa gaaacaactc
     2221 gacctggcac tgctcgtgtc ggaccgggag ggtccggtag ccggagtctt cacgaagaat
     2281 caagtcgtag cagcgccggt cattctcgat cgtctgcacc tcaagcaggg cgtcggccgc
     2341 gccttcctcg tcaatagcgg aaacgccaac gcctgtaccg gcccggaagg catgcaggca
     2401 gccaaggaga tggcgaagct ggcggcaacg gccctcaatt gcgcaccaca gaccattttc
     2461 gtcggatcca ccggggtcat cggtcaaccg ctcccgattg actgcatccg aaaagcgctt
     2521 cccgccctgt ctgcacgcat aacacgtagg ggcggagccg aagcggccgc ggcgatcatg
     2581 accaccgacc tcaaaccgaa acacgttgcc gtccgggctc tactcggcgg aaaaatggtg
     2641 actgtcggcg gcatggccaa gggatcgggc atgattcatc ccaacatggc cacgatgctg
     2701 ggctacctca ccaccgacgc ggccatcggg caacgggccc ttcaagcggc gctccgacag
     2761 gcggtcgatc aatcattcaa ttgcatcacg gtcgacggag ataccagcac gaacgacacg
     2821 gtgctctgcc tggccaacgg catggccgac aaccgcccta tcacacccgg ctcagccgat
     2881 ttcacacgct tctgcgcgat gcttgaaacg gtatgtcgca cactcgcgct gaaaatctgc
     2941 tgggatggcg aaggtgtgac gaaggtcgta cgggtggaag tgaagggagc acagtccacg
     3001 aaagcggcca aacaggtcgc ccaaacggtc gcaacttcca atctggtcaa aaccgcgctc
     3061 ttcggcggcg acgccaattg gggccgcgtc atggcggcgc tcggacgtgc aggcgtgccc
     3121 atcgaccctt cccgcatcag cctgcaattc gggggggtcc cgatggtgcg caagggacaa
     3181 ggactcggcc gcgcagccga acggcagttg accaaagtct tcaaagcgaa agagttcacg
     3241 attctcatcg atctggctca aggcaaggcc ggggcccaca tgt
//
LOCUS       DAOQPD010000160         3268 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_21405_length_3268_cov_21.469966, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000160 DAOQPD010000000
VERSION     DAOQPD010000160.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 3268)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3268)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3268
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_21405_length_3268_cov_21.469966"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(120..440)
                     /locus_tag="PK063_18605"
     CDS             complement(120..440)
                     /locus_tag="PK063_18605"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99115.1"
                     /translation="MSGRTITLRRVIWSLLAIWLFFGGVSFTEQVNSLLDTSDQDEQA
                     LSQLSLTLKPEIPPLPKQVTSSVVPIVLIPSVIHLADSSPSLSIPSQLLTLRPHQRVS
                     VYRI"
     gene            complement(566..1012)
                     /locus_tag="PK063_18610"
     CDS             complement(566..1012)
                     /locus_tag="PK063_18610"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99116.1"
                     /translation="MSRAVSLGDPSAVRRPEKQELEVITMAWYHERIAEEKLTVLIRY
                     LVHSFPLASILSRQVGDRYHVFIIVPFDGSPEKTLQVETTVFRNRSLRVEGFTALLST
                     LNLRRLFDQNDRYDLNWFGRQPKARHAATFYGASLPQASQISAALA"
     gene            complement(1368..1443)
                     /locus_tag="PK063_18615"
     tRNA            complement(1368..1443)
                     /locus_tag="PK063_18615"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1408..1410),aa:Ala,seq:cgc)
     gene            complement(1521..2192)
                     /gene="purN"
                     /locus_tag="PK063_18620"
     CDS             complement(1521..2192)
                     /gene="purN"
                     /locus_tag="PK063_18620"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HMZ99117.1"
                     /translation="MSAKAPRLVRLGVLASGRGSNLQAIIDAIEQHALSAEIAVVLSN
                     KQEAVALERARKHGAPAVWLDPKPFAGRPDSREAYDRAVQEVLQKHEVDLVLLAGYMK
                     IVTAVLVTAYQNRMMNIHPSLLPSFPGLDVQKKAIEHGCKIAGCTVHFVTEGVDEGPI
                     IIQAAVPIAEGDTPETLAARILEHEHRIYPRAIQLYAEGRLRVEGRRVFVAEPESPVT
                     GFHYP"
     gene            complement(2182..3219)
                     /gene="purM"
                     /locus_tag="PK063_18625"
     CDS             complement(2182..3219)
                     /gene="purM"
                     /locus_tag="PK063_18625"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HMZ99118.1"
                     /translation="MTTYRDAGVDIDAGDEFVERIKPHVRATFRPEVMTDLGGFGGLF
                     RFQANRYQDPVLVSGTDGVGTKLKIAFLMDKHDTVGIDLVAMCVNDIAVSGAEPLFFL
                     DYFATGKLSIATAAAVVKGISDGCRQAGCALIGGETAEMPSFYGEGEYDLAGFAVGVV
                     DRPKIIDGKQIVPGDVVIGLASSGVHSNGFSLVRKVLLERSGLTVTTAMPELGGTLGE
                     TLLTPTRIYAKQVLSLMESCPIKGIAHITGGGITDNLPRVFPARCGARIRRGSWPVLP
                     IFEAIRERGSVAVDEMYRVFNMGIGLILVVAPDHADRVMAKARELGEQAYHIGEMVAQ
                     QTEDGVVEYVG"
BASE COUNT          726 a          994 c          909 g          639 t
ORIGIN      
        1 cgtatcgatc gccgacgcaa ttccgaatca cctggccaat caccatgcgc acctatccac
       61 gcaagtcagc ggcacaaagc cgctacgcgc gggatcacga gactaggatg gcaaggagat
      121 caaatgcggt agacggagac acgttggtga ggacgaagcg tcagaagctg cgatggaatc
      181 gagagggacg gtgaactatc ggcgagatgg atgactgagg ggatcagcac gatggggacc
      241 acggaactcg tcacctgctt tggcagcgga ggaatttccg gcttgagggt caggctcagc
      301 tgggaaagcg cctgctcatc ctgatcgctc gtatccaaca ggctgttcac ttgttcagtg
      361 aatgagaccc caccgaaaaa cagccatatt gcgagcaggc tccagatgac gcgccggagg
      421 gtgatggttc gaccactcat cgttgaacag taatacgaac cacacaagga gtcaatgatg
      481 ccactgtcgc gacaccttgc tcccttctca tggattcatc gggctctggg gaaaaaccaa
      541 cggcttcggt gccccgcctg ctgtctcacg cgagcgctgc cgaaatctga gaagcttgcg
      601 gtagggatgc cccgtagaat gtggccgcat gcctcgcctt tggctggcga ccgaaccaat
      661 tgagatcgta gcgatcattc tgatcgaaca ggcgacgaag attcagtgtt gacagaagag
      721 cggtaaatcc ttcgacccga agacttctgt tgcgaaagac tgtcgtctcg acctgcaatg
      781 ttttttctgg tgacccatcg aatggcacga taataaacac gtgataccgg tctccgactt
      841 gccgagacaa aatactggcc agggggaaac tgtgaaccag ataccggatc aacaccgtga
      901 gtttctcttc ggcgattcgt tcgtggtacc aagccatggt gatcacctcc agttcctgct
      961 tctcggggcg ccgcactgcc gatggatcgc caagcgaaac tgccctgctc atcgttcaga
     1021 ccaacgggct ggcctggtca gcaacccaag cgtggcgaga ccacagatca atgctaagag
     1081 cagtagactc gccaccagaa acagccatgc ttttatctct tgcgtcatgc ccgtatccta
     1141 cggcttcccg gttcggccat ggacctaggg aaaccgctgg aatgtgatta ggagtactct
     1201 cgtttacagg ctctcgtaga gctgccgatg cgccttacga cgtgaagttg ccgaggaatg
     1261 tgcgcccaga tagcgagctt atgcagaagt gtagaaagag aggcggttaa cagattattg
     1321 gggatggacg aaccggacgg aatggcttgc gtggatgaga aggaaagtgg tggagggcag
     1381 gggagttgaa cccccgaccc ctacgttgcg aacgtagtgc tctcccaact gagctagccc
     1441 cccacaacca ggccgcatta tacacaaccg gcgccgcagt ctctagcggg ctacggaaaa
     1501 agtctcgacg aggtcttcta tcagggatag tggaaaccgg tcaccggaga ttcgggctcc
     1561 gccacaaaga cccgccgtcc ctccactcgc aaccgccctt cggcatagag ctggatggct
     1621 cgcggataaa tgcggtgttc atgctcgaga atgcgagccg ctaacgtctc gggcgtgtct
     1681 ccctctgcga tcggtactgc cgcttgaatg atgatcggtc cttcgtccac cccttcggtg
     1741 acgaagtgca ccgtacagcc ggcaattttg cagccgtgtt caatggcttt tttctgcaca
     1801 tctagccctg gaaacgacgg gaggagtgac ggatggatat tcatcatgcg attttgatat
     1861 gccgtgacca gcaccgctgt gacaatcttc atgtatcccg ccagcagcac cagatccact
     1921 tcatgcttct gcaagacctc ttggacagcc cgatcatagg cctcacgact atccggtctg
     1981 ccggcgaagg gtttgggatc gagccagacc gccggcgcgc catgcttgcg cgctctttcc
     2041 agagcgacgg cctcctgctt gttgctcagc accaccgcaa tctcggccga cagcgcatgc
     2101 tgttcgatgg cgtcgataat cgcctgcagg ttcgacccgc gtcccgaggc caatacaccg
     2161 agccgcacca gccgaggggc tttagccgac atactcgacc accccgtctt cggtctgctg
     2221 cgcgaccatc tcgccgatgt gataggcctg ctcccctaac tcgcgagcct tcgccatgac
     2281 ccggtcggca tggtcgggag cgacaaccag gatcaagccg atccccatat tgaagacgcg
     2341 atacatttcg tctacggcca ctgatccgcg ttcccggatc gcctcgaaaa tcggcagcac
     2401 cggccaggag ccacggcgaa tccgtgcgcc gcaacgcgcc ggaaaaaccc gtggcaggtt
     2461 gtcggtgatg cccccgccgg tgatatgggc aatccctttg atcggacaag attccatcag
     2521 cgacagcacc tgcttggcgt agatgcgcgt gggcgtcagc aaggtttccc caagtgtccc
     2581 gcccaattcc ggcatggccg tggtgacggt cagcccgctc cgctcgagca acaccttcct
     2641 gacgagggaa aagccgttgc tgtgcacacc gctcgaggcc aacccgatga ccacatcacc
     2701 cggaacgatc tgctttccat cgatgatctt cggccgatcc accacaccca cggcaaaccc
     2761 ggccaggtcg tactcacctt cgccgtaaaa cgagggcatc tcggccgttt ctcccccgat
     2821 caaggcacat ccggcctgtc ggcagccgtc ggaaatgcct ttcaccaccg ccgccgccgt
     2881 cgcgatcgac agtttaccgg tggcaaaata gtcgaggaag aacaggggct ccgcgccact
     2941 cacggcaata tcgttcacac acatggccac caggtcgatg ccgaccgtgt catgtttatc
     3001 catcagaaag gcgatcttga gtttcgtccc gacgccgtcg gtccccgaca cgagcaccgg
     3061 gtcctggtac cgattggcct ggaaccggaa gaggccgccg aagccgccca gatccgtcat
     3121 cacttcaggg cgaaacgtgg cccgcacatg cggcttgatc cgctcgacga attcatcgcc
     3181 ggcatcgata tcgactccgg catcacgata agtagtcatt ggggtcgcat cttaacgagc
     3241 caactgatag cgggtcaaca atagtctc
//
LOCUS       DAOQPD010000161         3257 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_21528_length_3257_cov_24.148032, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000161 DAOQPD010000000
VERSION     DAOQPD010000161.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 3257)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3257)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3257
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_21528_length_3257_cov_24.148032"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..299)
                     /locus_tag="PK063_18630"
     CDS             complement(<1..299)
                     /locus_tag="PK063_18630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HMZ99119.1"
                     /translation="MLIGVPKEVKDFEYRVSVTPDGVRLLRQHGHQVLVEPSAGQGSG
                     FSDEAYRQAGADVVGSKEEVFKRAELIVKVKEPQLAECALFRPGQVLFTYLHLAS"
     gene            467..835
                     /locus_tag="PK063_18635"
     CDS             467..835
                     /locus_tag="PK063_18635"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99120.1"
                     /translation="MDAGSCNACNTAGTPLMKLSLGKDFFGRTYDRLSPSSDQSPKWY
                     CEPCSMMKNLQRDFRDIRTEFDKLATGQASALSEPEAKQRAQLRLREISAIAGSQTAG
                     SSLLNPADVKQLIDQFHARA"
     gene            883..1233
                     /locus_tag="PK063_18640"
     CDS             883..1233
                     /locus_tag="PK063_18640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S) ferredoxin domain-containing protein"
                     /protein_id="HMZ99121.1"
                     /translation="MTGYQRHIFVCTNKREPDDPRGSCSKLGSESLHACFKQEAKRLN
                     LKGIVRANKAGCLDYCAQGPSVVVYPEGIWYRVRTEADVKEIMERHIVNGEPVERLLM
                     PDQARPSLLSPLKP"
     gene            1297..1680
                     /locus_tag="PK063_18645"
     CDS             1297..1680
                     /locus_tag="PK063_18645"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99122.1"
                     /translation="MEKVAFMKAFPGLLSTWDQLKGKTVEAVLPLKSKTGSSAIICTD
                     GSFVVVPLLSPEPYELGEALQAGREYLEPKHPEAYVGYDRLRKKDQDAQRTARLENIL
                     GAIQNNVEQIPELKDRLAQLVKEWK"
     gene            1677..1973
                     /locus_tag="PK063_18650"
     CDS             1677..1973
                     /locus_tag="PK063_18650"
                     /inference="COORDINATES: protein motif:HMM:NF024246.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99123.1"
                     /translation="MSSLPQKNMFEIFSQGLFEGVKPMLVIRDHLVRHPDRCTHQAIC
                     VPICPTSAWLSTPPYKFDPSRCLESCRLCLDACPSQAIYAVFRKGEKLLEPQKK"
     gene            complement(1998..2999)
                     /locus_tag="PK063_18655"
     CDS             complement(1998..2999)
                     /locus_tag="PK063_18655"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF012705.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="HMZ99124.1"
                     /translation="MLKQVSRSFYLTLNVLPSDVRDEMGLAYLLARAADTIADTELIG
                     RAERLRYLTMFRAQFAGDEVQPQAVQAIQTGLLPHQTDSAERVLLERLPECLALYRQF
                     EQGDRDRIRWLMEVLPNGMEMDLTRFPGSSAQDLTALERPEELDRYTYFVAGCVGEFW
                     TRMVCAHRPAMRRWDVDRMSAVGVRFGKGLQLTNIVKDVARDLHNGRCYVPTQWLDEV
                     GLKPTDLLKPESLPTFRPILLRMIRQAVEHLDQGWLYTMALPRLEIRQRLACMWPILL
                     AGETLKRVATATDLLDPRVNVKAPRSVVYRVMALTTVTGGCGYVGTAYWGRLRKQIM"
     gene            complement(3051..>3257)
                     /locus_tag="PK063_18660"
     CDS             complement(3051..>3257)
                     /locus_tag="PK063_18660"
                     /inference="COORDINATES: protein motif:HMM:NF012355.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HMZ99125.1"
                     /translation="ITTITPHNFVLRDEAAGLSIERDVSAGKTVTVQFTPTKPGTYAF
                     YCDKKLLFLPSHREKGMEGTLEVR"
BASE COUNT          713 a         1001 c          895 g          648 t
ORIGIN      
        1 aaggaagcga ggtgcaaata agtaaacagg acctgaccgg gccggaacaa cgcacattcg
       61 gctagctgcg gctccttcac tttcacgatg agttcggccc gtttgaacac ctcttccttg
      121 gagcccacga cgtccgcgcc ggcttgacga tacgcctcat ccgaaaaccc gctcccttgt
      181 ccggccgatg gctcgaccaa cacctgatgg ccatgctgtc gcaacagacg cacgccgtca
      241 ggcgtcacac tcacgcggta ttcgaaatct ttaacttctt taggaacgcc aatcagcatg
      301 cgcgcctcct cgccccagtc accagtgctc ctgttgttgt ctacattata ccccgaaccg
      361 cactctgtat atgcgtgcct cgctccacca ccttgcgagg ggaaagagca gtgcggtaag
      421 attcgatctc tttggttctt tccccttgaa gaggagcact tcgcgcatgg atgccggatc
      481 ctgtaatgcc tgcaacaccg caggtacacc gttgatgaaa ttgtcgttgg ggaaagattt
      541 tttcggtcgc acctatgacc gattgtcgcc ctcctctgac cagagcccga aatggtattg
      601 tgaaccctgc tccatgatga aaaatctgca gcgcgacttt cgtgatatcc ggacggaatt
      661 cgacaaactc gccacgggac aggcctctgc cctgtctgag ccagaggcga aacagcgcgc
      721 gcaattgcgt cttcgagaaa tttccgccat tgccggcagt caaactgccg gctcgtcact
      781 cctgaaccca gcggacgtga agcaactgat cgaccagttc cacgcgcgtg cctgagctcg
      841 caattaccag cttgaaccac ataacacact gacatcctga cgatgaccgg ctatcaacga
      901 catatatttg tatgcaccaa caagcgcgag cctgatgatc cccgcggcag ctgttccaag
      961 cttggatcag agtcgcttca tgcctgtttc aaacaagagg ccaagcgact caatttgaag
     1021 ggcatcgtgc gtgcgaataa ggccggctgc cttgactatt gcgcccaagg acccagcgtg
     1081 gtggtctatc ccgaaggcat ctggtaccgc gtgcggactg aagccgacgt gaaggaaatc
     1141 atggagcgcc atatcgtgaa cggagaaccg gtcgaacgac tcctgatgcc tgatcaggcc
     1201 cggccttccc tcctctctcc gctgaaacct tgagccgggt cgtccaccat agctcgcgag
     1261 atctgtatgc cagccgatga aaaatggaag gccaacatgg aaaaggtggc cttcatgaaa
     1321 gcgtttcccg gtttgctcag cacctgggat cagctgaagg gcaaaaccgt ggaggccgtg
     1381 ttaccgctca agagcaagac cggatcctcc gcgatcatct gcaccgatgg atcgtttgtg
     1441 gtggtcccgc tgctcagtcc ggaaccatac gagctgggcg aagcgcttca ggcaggccgg
     1501 gagtacctcg agccgaagca ccctgaggcc tacgttggat atgaccggtt gcgcaagaag
     1561 gaccaagatg cgcaacgcac cgcgcgcctc gaaaatattc tcggcgccat tcaaaataat
     1621 gtggagcaga ttccggaatt gaaggaccgg ctggcacagc tggtcaagga gtggaagtga
     1681 gcagtctccc gcaaaaaaac atgttcgaga tcttttcgca gggtctcttc gaaggagtga
     1741 aaccgatgct ggttatccgc gatcatcttg tccgccatcc tgaccgctgc acccaccaag
     1801 ccatttgcgt gcccatttgc ccgaccagcg cctggctttc gacccctccc tacaaattcg
     1861 acccgtcccg ctgcctggaa agctgccggc tctgcctgga tgcctgcccc tcccaagcga
     1921 tctatgccgt gttcagaaaa ggtgagaaac tgttagagcc gcagaagaag taacgggtcg
     1981 atcgacgccc tacgcgtcta catgatctgc tttcgtaaac gcccccagta ggccgtcccc
     2041 acatagccgc aaccgccggt cacggtcgtg agcgccatca ctcggtagac caccgagcgc
     2101 ggggctttaa cattcacgcg ggggtcgagc agatcggtcg ccgtggccac acgtttcagc
     2161 gtttcaccgg ccaacagaat cggccacatg caggcgaggc gttgccggat ttccaaccgc
     2221 ggcagcgcca tggtgtagag ccaaccctgg tccaaatgtt ccaccgcctg acggatcatc
     2281 cgcaggagga tggggcgaaa ggtcggaagg ctttcgggtt tgagcagatc cgtcggtttg
     2341 agccccactt catccagcca ctgcgtcggc acgtaacacc gaccgttgtg aaggtcgcgg
     2401 gcgacatcct tcacaatgtt cgtaagctgt aaccccttgc cgaagcggac gccgaccgcg
     2461 gacatccggt cgacatccca gcgcctcatc gccggccgat gtgcgcagac catgcgggtc
     2521 caaaactctc ccacgcagcc ggcgacgaaa tacgtatacc gatccaactc ttcgggacgc
     2581 tccagcgcgg tgaggtcctg ggctgatgac ccgggaaacc tggtcaggtc catttccatg
     2641 ccgttcggca gcacctccat gagccagcga atgcgatcgc gatccccctg ctcaaactgc
     2701 ctgtagagag ccaggcactc cggcagccgc tccagaagca cgcgctcagc cgagtcggtc
     2761 tggtgcggca gcagtccggt ctgaatggcc tgcacggcct gcggctgaac ctcgtcgcct
     2821 gcgaactgcg cgcgaaacat ggtgagatat cgaaggcgct ccgcccgccc gatcagctcg
     2881 gtgtcggcga tggtgtcggc cgctcgcgcg agcagatagg ccaggcccat ctcgtcgcgc
     2941 acatccgacg ggaggacatt caacgtcagg taaaatgaac gggatacctg cttgagaatg
     3001 acgtggagga gttcgtgctt ggaaggctga atactcgtgg cgcaccctgc ttatctgact
     3061 tcgagtgtcc cttccatacc tttctcccga tgacttggaa gaaataggag cttcttatcg
     3121 caatagaaag catacgtgcc tggcttcgtc ggggtaaatt gcaccgtgac cgttttaccg
     3181 gcgctgacat cccgttcgat cgagagcccg gcggcctcat cccgcaagac aaaattgtgc
     3241 ggagtgatcg tggtgat
//
LOCUS       DAOQPD010000162         3229 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_21850_length_3229_cov_24.101449, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000162 DAOQPD010000000
VERSION     DAOQPD010000162.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 3229)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3229)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3229
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_21850_length_3229_cov_24.101449"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..196)
                     /locus_tag="PK063_18665"
     CDS             complement(<1..196)
                     /locus_tag="PK063_18665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99126.1"
                     /translation="MPHAASDRCLGMVNQMNDLAVRVEHLHKRYRLGSTHEHDGSLAG
                     ALSRGMRQLVGRRSAPPPTDD"
     gene            complement(213..479)
                     /locus_tag="PK063_18670"
     CDS             complement(213..479)
                     /locus_tag="PK063_18670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HMZ99127.1"
                     /translation="MELHDRLEEVFRQVFDNEALELRDQMKAADIEGWDSVAHINLMF
                     GIEQAFGIRFKGNELADMKNIGELKDFLAGKLNGEASPMRKVLP"
     gene            complement(565..2112)
                     /locus_tag="PK063_18675"
     CDS             complement(565..2112)
                     /locus_tag="PK063_18675"
                     /inference="COORDINATES: protein motif:HMM:NF024950.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HMZ99128.1"
                     /translation="MARPDLSSSTQCFLPHMITVRFTKQDLARFSAASRDRNPLHISE
                     DYARTTPYAEPVVFGVLSLLAGLGHLSTRHGKQLQHLSVEFRNPLSLDVPYCLDIIES
                     STDNARVKLYDTTRLMMTATFAFMPGQGNPESRRFSETSCATEPEDRKKDSLLPGTRV
                     TGTYAPHTEAFAQVVDRWELEGKGATPYQLAAMMWASYVVGMHLPGKRAVLWRLTLDF
                     HDVEPPGQEPFSYEATVEDLDERYDLLRCRGTLSAGSLPYATAHMSAFVRQDSPRSSL
                     RRISDLLPESEQLKGKRALIIGGSRGLGAAIAQALISQGCSVLLSYQQSTAEAEQLRA
                     SVGDRSTQLELVQGDAADIEWCLSLRDMILSRYGGLDLLVCNASPPIRPLAFEPEKFT
                     QFQDFLTKSLALVSAPMSTFLGLLAHQAGWNIILSSSYVKELPAAFAHYVTAKCALEG
                     LVNWAAVQYPTVRHRIVRPPKLLTDQTNTTIGRQGAMDVEQVAVSIVRQICQPHQPAA
                     VQIMETF"
     gene            complement(2099..>3229)
                     /locus_tag="PK063_18680"
     CDS             complement(2099..>3229)
                     /locus_tag="PK063_18680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIIC family phosphatase"
                     /protein_id="HMZ99129.1"
                     /translation="AAVIAADLGLSRKCLVLDLDNTLWGGVIAEEGLAGIKLGQGPEG
                     EAFVAFQEYLLKLKRKGVILTVCSKNNYADAIHPFEKHPEMRLRLQDIALFIANWESK
                     PDNIRRIADTLQIGLDSLVFVDDNPVERDIVRKFLPEVDVLPLPDDPAYYTRALSQYL
                     SLETASLTAEDSERADQYRARAQIKELEAAAGSIEDFYLSLRMQAIVTPFEESQLPRI
                     AQLIGKTNQFNLTTRRHGMPQLTAFIQSTDYVHLALRLRDRYTDHGLVSVMIAQCRGE
                     VLDIDTWLMSCRVIGRTVEATMLELLCRHAAQLGCTILQGTYIPTQKNAMAADVYAKH
                     GFEPFNQTNGHHVWRYDLTANGPIANPFVKRVDAWESVDGTP"
BASE COUNT          664 a          899 c          961 g          705 t
ORIGIN      
        1 tgtcgtcggt gggcggcggg gcagagcggc ggccgactaa ctggcgcatg ccccgcgata
       61 aagccccggc gagagatccg tcatgctcat gggtagagcc caatcgatac cgcttgtgca
      121 aatgttcgac gcgaaccgcc aggtcattca tctgattcac cattccgagg cagcgatcgc
      181 tagctgcatg tggcatgctc cgcagatgcg ccttagggga gaacctttcg catgggggac
      241 gcttcgccgt tcaacttgcc ggccaaaaaa tccttcagct cgccgatatt cttcatgtcg
      301 gccaactcat tgcctttaaa tcggattccg aacgcctgct cgatgccgaa catcagattg
      361 atatgcgcca cggaatccca gccttcgata tcggcggctt tcatctgatc gcgcagctca
      421 agcgcctcat tgtcgaatac ttggcgaaag acttcttcca atcgatcgtg cagctccatg
      481 aactcctcac atcatgcggt taggtgtcgt atggtcattg gtcgggtaaa agacttgtgc
      541 ctgttaggtc gttgtcatgg cccgtcaaaa tgtctccatg atctgcacgg ccgctggttg
      601 gtggggctga cagatctgtc gcacaatgga gaccgcgacc tgttcgacgt ccatggctcc
      661 ctgccgtcca atggttgtgt tggtctgatc ggtcaaaagt ttgggcggcc tgacaatacg
      721 atgccgaacg gtcgggtatt ggacggcagc ccagttcacc aagccttcca gcgcgcattt
      781 tgccgtcacg taatgcgcga aggctgccgg aagctctttc acataggatg acgacaggat
      841 gatgttccat cctgcctgat gagccagcaa gccgagaaac gtggacatcg gcgcggagac
      901 cagtgccaga cttttcgtga ggaagtcctg gaactgcgtg aatttttccg gttcgaatgc
      961 aagcggacga atcgggggcg aggcattgca gacgagaagg tcgaggcctc cgtaccgtga
     1021 gagaatcatg tcccgtaaag acaggcacca ttcaatatct gcggcgtcgc cctgcaccag
     1081 ttcaagctga gtcgaccggt cacccacact ggcgcgaagt tgctccgctt ccgccgtact
     1141 ctgctggtag ctcagcaaca cggagcagcc ctgtgaaatg agcgcttgcg cgatggcggc
     1201 gccaagaccc cggcttcccc cgatgatcag cgcgcgcttt cccttcaatt gttcggattc
     1261 cggtagcagg tcgctgatgc gtcgaagcga agatcgagga gaatcctgtc gcacgaatgc
     1321 cgacatgtga gccgtcgcat aggggagcga gccggcagaa agggtgcccc gacatcgcaa
     1381 gagatcatat cgctcatcga ggtcttcaac ggttgcctcg taggagaacg gttcttggcc
     1441 tggtggttct acatcgtgaa aatcaagcgt cagccgccag agcaccgcgc gtttgccggg
     1501 aaggtgcatg cctacgacat aactcgccca catcatggcc gcgagctggt atggggtcgc
     1561 gccttttccc tcgagctccc agcggtcgac cacctgcgcg aacgcttcgg tgtgtggcgc
     1621 ataggtgccg gtcacgcgag tgcccggaag gagggagtct ttttttcgat cttccggctc
     1681 cgtagcgcaa gatgtctccg agaagcgccg tgattcagga ttgccctgtc ctggcatgaa
     1741 ggcgaatgtc gccgtcatca tcagacgagt cgtatcatag agtttgacgc gtgcgttgtc
     1801 tgtcgacgat tcgatgatgt cgagacaata gggcacgtcg aggctgagag gattacgaaa
     1861 ttcgaccgag agatgctgca gctgcttgcc atggcgtgtc gaaagatggc ccaatcccgc
     1921 caggagactc aacacgccga acaccactgg ttcggcataa ggcgtcgtgc gggcatagtc
     1981 ctcggagatg tgcaggggat ttcggtcgcg gcttgccgcg ctgaagcgtg caagatcctg
     2041 tttcgtaaag cggacggtta tcatatgagg caggaagcat tgagtcgaac tcgacaagtc
     2101 agggcgtgcc atcaacggat tcccatgcat cgacgcgttt cacaaacgga ttggcaatcg
     2161 ggccgttcgc tgtcaggtca taccgccaca cgtgatgccc attggtctgg ttgaagggct
     2221 cgaaaccgtg tttcgcatag acatctgctg ccatcgcgtt cttctgggtc gggatatacg
     2281 ttccttggag gatagtgcag ccgagctggg cggcatgccg gcagaggagt tccagcatgg
     2341 tcgcttccac ggtgcggccg atgacccggc aactcatgag ccaggtgtcg atatccagaa
     2401 cctcgccccg gcattgcgca atcatgacac tgaccaggcc atgatcggtg tagcgatccc
     2461 gcagccgcaa ggcgaggtgc acgtagtcgg tgctctgaat gaaggcggtc aactgcggca
     2521 tgccgtgtcg tctggtggtc agattgaatt ggttggtctt gccgatcagt tgcgcgattc
     2581 tcggcagctg tgattcttcg aagggcgtca cgatcgcctg catgcggagg ctgagataga
     2641 aatcctcgat cgacccggcc gcagcctcca actctttgat ctgcgccctg gctcgatact
     2701 ggtcggctcg ctcactatcc tcggccgtca aagaggcggt ttcgagcgac aggtactgcg
     2761 acagggccct ggtgtaatag gccggatcgt caggcaacgg aaggacatcg acctcgggaa
     2821 gaaatttgcg gacaatgtca cgttcgaccg ggttatcgtc gacaaacacg agactatcca
     2881 gcccgatctg tagggtgtcg gcgatccggc ggatgttgtc cggcttggat tcccaattcg
     2941 cgatgaaaag ggcgatgtcc tgcagcctga gccgcatctc aggatgtttt tcgaacggat
     3001 gaatggcatc ggcatagtta ttctttgagc agacggtcag gatgacgcct ttccgtttca
     3061 gcttgaggag atattcctga aatgccacga atgcctcgcc ttccggtccc tgtcctaatt
     3121 tgattccggc gagaccttct tccgcgatca ctccgcccca taaggtgttg tcgagatcga
     3181 gtacgaggca cttacggctc aagccaaggt ccgcggcgat cacagccgc
//
LOCUS       DAOQPD010000163         3221 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_21960_length_3221_cov_21.195515, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000163 DAOQPD010000000
VERSION     DAOQPD010000163.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 3221)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3221)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3221
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_21960_length_3221_cov_21.195515"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(152..850)
                     /gene="cmk"
                     /locus_tag="PK063_18685"
     CDS             complement(152..850)
                     /gene="cmk"
                     /locus_tag="PK063_18685"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: protein motif:HMM:NF014300.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - cytidylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HMZ99130.1"
                     /translation="MGEIGVASRGKRGLIIAIDGPAGVGKSTVARLLALRLGYLYLDT
                     GALYRAIAWKVHNAGLSPDDHLAIAALLPKTTLQMACGPEQSHVLLNGRDITGELRTP
                     AVSALASMVSAIPAVREWLLPVQRQIGAEGCVVAEGRDIGTRVFPEADVKFFLEADAE
                     VRATRRHRELVAAGHSVQFDQTKRDLTGRDDRDRTRAVAPLIPASDAERLDTSSLPVE
                     EVVSHMMAVVAARL"
     gene            complement(863..2191)
                     /gene="aroA"
                     /locus_tag="PK063_18690"
     CDS             complement(863..2191)
                     /gene="aroA"
                     /locus_tag="PK063_18690"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HMZ99131.1"
                     /translation="MASLTITPGRPLKGTITVPGDKSVTHRAIILTALAEGSSTVKEY
                     CRGEDCLNTMRAFQSLGVRIEETPESLTVYGKGMWGLTEPFGPIDCGNSGTGIRLMAG
                     LLAGQDFFTVLTGDESIRRRPMGRVVKPLRAMGATIAGRKGGELAPLAITGTRLKGLS
                     YVSPVASAQIKSSLLFAALYADGLTTISEPRLSRDHTERMFAYFGIPFERDGCTVRIE
                     GRPSVRWSGKPVLVPGDLSAAAFFLVGASIVPGSDVTVRNVGMNPTRTGLIDILREMG
                     AHIEVLNPREEAGEPVADLRVLSRPLHGVRIGPDQIPQTIDEFPILCVAAAVAEGETV
                     VTGAEELRVKESDRIATMAKELRAMGARIEERPDGMVIQGLGHNGANGALAGAICESH
                     GDHRVAMSVAIGGLTAAQATQIQNTACIETSFPNFDRKLLELLTDSGKRL"
     gene            complement(2198..3094)
                     /locus_tag="PK063_18695"
     CDS             complement(2198..3094)
                     /locus_tag="PK063_18695"
                     /inference="COORDINATES: protein motif:HMM:NF014234.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004665 - prephenate dehydrogenase (NADP+)
                     activity [Evidence IEA];
                     GO_function: GO:0008977 - prephenate dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_process: GO:0006571 - tyrosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase/arogenate dehydrogenase
                     family protein"
                     /protein_id="HMZ99132.1"
                     /translation="MTTPHFKQAAIIGVGLIGGSLGMILRRQKLADSVVGIGRRVENL
                     KTAVEVGAIDRYVSDPREGVEQADFVLLATPVDTYERHLQEWAGCLKPDTIVSDVGSV
                     KGELVTRAEALMPSGVKFVGAHPIAGKEKTGVAAGSETLFSGARCILTPTTHTDPEAL
                     KVVRKIWELAGSIVLEMDPFLHDKILGAVSHLPHVAAFALMTALADVRDHGVPELDLA
                     GHSGGGLRDTTRIAASSPEMWRDIFLWNRDNVVSLIETYERHLGELKRLIAAGDAAGI
                     EKQLDKAKYEREQLIPRTPGKA"
BASE COUNT          682 a         1044 c          878 g          617 t
ORIGIN      
        1 cagcccagca aaggaatatc caagtaactg gcgtggttcg aggcgatcaa caccccgccc
       61 ttccgcggca cctgaccgat ggtgcgatac cggaaacaga gccagccgat gatgcgagag
      121 aggacccaca agaggccata cagggcggag ctcacaatcg cgccgcaact acagccatca
      181 tgtgcgagac gacctcctcc accggcaggc tcgacgtatc gagccgctcc gcatcggatg
      241 cgggaatcaa gggcgccacc gcgcgggtac ggtcacgatc gtcgcgcccg gtcaggtcgc
      301 gcttggtctg atcaaattgc actgagtgcc ccgccgccac cagttcgcga tgccgccgcg
      361 tagctcgaac ttctgcatcg gcttcgagga aaaattttac gtcggcttcc ggaaataccc
      421 tggttccgat gtcacgccct tccgccacca cacacccttc agcgccgatc tgccgttgca
      481 cgggcaacag ccattcgcga acggcgggaa tggctgagac cattgacgcg agcgcgctca
      541 ctgccggagt tcgcaactca cctgtaatat cgcgcccgtt caggagcaca tgggattgtt
      601 cagggccaca ggccatctgc agggttgtct tgggaagcaa cgcagcaatg gcaaggtgat
      661 cgtcaggact gagtcccgca ttgtggactt tccacgcaat ggcccgatac aaggcaccgg
      721 tatccagata gagatatccg agccgcaagg ccaacagtcg cgcaaccgtg ctcttcccca
      781 cgccggccgg gccatcgatg gcgatgatca agccacgctt gccgcggctg gcaaccccaa
      841 tttcacccac gcgatcctcg cactatagac gtttcccaga atcagtcaac agttccaaga
      901 gcttacgatc aaaattcgga aaggatgttt cgatacaggc cgtattctga atctgcgttg
      961 cctgggccgc agtcaacccg ccgatcgcta cagacatcgc cacacgatga tcgccatgac
     1021 tttcacagat ggcgccggcc agcgcaccat tggcgccgtt gtgtccgagc ccctgaatga
     1081 ccataccgtc tggccgctct tcgatacggg ctcccatggc ccgcaactct ttcgccatgg
     1141 tcgcaatccg gtcgctttcc ttcacgcgca gctcttcagc gccggtgacc acggtttcac
     1201 cttccgccac ggctgccgcc acacagagga tgggaaattc atcaatggtc tgaggaatct
     1261 gatcgggtcc gatgcgtacg ccgtgaagcg gtctggagag cacccgcaaa tccgctaccg
     1321 gctcccctgc ctcctctcgc ggattcagca cctcgatatg cgcgcccatc tcacgcagga
     1381 tatcgatcag tccggttcgc gtcggattca tgcccacgtt gcgaaccgtg acatcggaac
     1441 ctggaacaat ggaggcaccg accagaaaaa atgccgcggc cgacaggtcg ccagggacca
     1501 gcaccggctt accgctccaa cggaccgaag gacgcccttc gatccggacc gtgcatccgt
     1561 cccgctcgaa cggaatgccg aaatacgcga acatacgttc ggtgtgatct cgcgagagcc
     1621 ggggctcgga aatggttgtg aggccgtccg catagagggc cgcgaaaagc agtgacgatt
     1681 tgatctgagc gctcgcaacc ggcgaaacat aggacagacc cttgagcctg gtccccgtga
     1741 tcgccaaggg cgcaagctcc ccgcccttcc gcccggcaat agtcgcaccc atcgcccgca
     1801 acggcttgac cacccgcccc atgggacggc gcctgattga ttcatctccc gtgaggaccg
     1861 taaaaaaatc ctgccccgcc agcaatccgg ccatcagccg aataccggtt ccggaattcc
     1921 cgcaatcgat gggaccgaat ggttccgtca gtccccacat gccttttccg tagaccgtca
     1981 gcgattccgg cgtctcctcg atccgtaccc ccagcgactg gaaggcacgc atagtgttca
     2041 gacagtcttc accacgacag tactccttca cggtgctcga tccttcggcc aaggccgtga
     2101 ggatgatggc ccgatgcgtg acggacttat cgcccggcac cgtgatggtg cccttcaacg
     2161 gacgacctgg agtaatcgtt aacgaagcca tcgcagctta ggccttcccc ggtgtccggg
     2221 ggatgagttg ttcacgttcg tacttggcct tgtccaattg cttttcaatt ccagcggcat
     2281 cgccggcggc aatcagccgt ttgagctcac cgagatggcg ttcataggtc tcgatcaacg
     2341 acacgacgtt gtcccgattc cagaggaaaa tatctctcca catttccggc gaactggcgg
     2401 cgatccgggt ggtgtcacgc aagccgccac cggaatgacc agccaggtcc agttccggca
     2461 cgccatggtc gcggacatcg gctaaggccg tcatcaatgc aaaggccgct acatgcggaa
     2521 ggtggctgac agcaccgaga attttatcgt ggagaaaggg atccatctcc agcacaatcg
     2581 aacccgcgag ttcccagatt ttacgaacaa ccttcagggc ctcgggatct gtgtgggtgg
     2641 ttggcgtcag aatgcagcgt gcaccggaaa agagcgtctc ggagccggct gccaccccgg
     2701 tcttttcttt gccggcaata ggatgtgcgc cgacaaattt aacccctgac ggcatcaggg
     2761 cctcggccct cgtgaccaat tcccccttca cactgccgac atcgctcacg atggtatcgg
     2821 gcttgagaca gccggcccat tcctgcaagt gccgctcata agtatccacc ggtgtggcca
     2881 gcaggacaaa atctgcctgt tcaacgcctt cgcgcggatc agacacgtat cgatcgatgg
     2941 cgccgacctc aaccgccgtt ttcagattct ccacgcggcg accgatgccg acaactgaat
     3001 cggccagctt ctgacggcgc aggatcatcc ccagggagcc gccgatgagt ccgactccga
     3061 taatggccgc ttgtttgaaa tgtggtgtcg tcatgaggta attggctgat ccttgggaca
     3121 ttccctggtc aacgtcgctc cgcgatccct tacaatgtgc gatcgacggc agcagcgatc
     3181 ttgcgcaagt ctcccatcag ttctttaaat ttcgacggcc g
//
LOCUS       DAOQPD010000164         3219 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_21981_length_3219_cov_20.885904, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000164 DAOQPD010000000
VERSION     DAOQPD010000164.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 3219)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3219)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3219
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_21981_length_3219_cov_20.885904"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..464)
                     /locus_tag="PK063_18700"
     CDS             complement(<1..464)
                     /locus_tag="PK063_18700"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99133.1"
                     /translation="MTVIYHSGTDQTHVIKDFMNIRPEGVRAPICHPTTRIRTCLLVM
                     LCAGLGACALVPGDKAYGLRDHQSAVKLPVRQEPAAEPVPDNVTIKPITAELIIEQMK
                     QAAAERPAANASQMNGRSGVGPMPASPDYKVGPGDVLTVVVWDHPELTTPAG"
     gene            complement(519..956)
                     /locus_tag="PK063_18705"
     CDS             complement(519..956)
                     /locus_tag="PK063_18705"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: protein motif:HMM:NF013607.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HMZ99134.1"
                     /translation="MYQRILVVCTGNICRSPMGEYLLRSRLAEAGKAGEIRSAGVGAL
                     VGEPAEPEAIERMQALGIDLSPHRAQQASVALCRWAELVLVMEPHHREALGDIDPTVR
                     GKTFLLGYWGKFEIPDPYRRSAAAWDEAAALIDTGIGQWVARL"
     gene            complement(972..2486)
                     /locus_tag="PK063_18710"
     CDS             complement(972..2486)
                     /locus_tag="PK063_18710"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: protein motif:HMM:NF013146.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HMZ99135.1"
                     /translation="MFSLALFLLGTVVSAVAIRYGIVAAHHFGVVDKPGGHKAHDTVT
                     PFVGGIGVVCAFMCAVGVVASGSNGFPFRLDAMAAGVLIMFITGFADDLLNLHYRIRL
                     CIQAMVGVIMIFGGGVVLRDFGHLGSASVVSLGYVGIPLTLIATIGAINALNMIDGID
                     GLSGSISLVSLVLIALALHHSGNVAYFSLVMIIAGGVAGFLIYNLRYPGHRRARCFLG
                     DNGSMVLGYAFAWLLSDLCQETKGVRVITPVTTLWLFAVPLIDTLCVMMRRVWMGGSP
                     FRADRYHLHHLFQRAGFRVQDTVFILASVQLFFGAVGLAGMYAGISEIVMLAAFGVLF
                     GLCFLVILRPWRFVPALRRVHRLLGLTSVQAVGVYVGGLTETGLMTFSKALKRDFANL
                     YDFQFSVYRQLDDITEEERSFGVVELLTEDKALIPLQIGHIKGTLKREFQGSEGLVVR
                     EFVARNAGNDRRSAEKGRPAERRSRDRRSQRKPQALLRTVCEAGDVNLLSISKG"
     gene            complement(3077..3152)
                     /locus_tag="PK063_18715"
     tRNA            complement(3077..3152)
                     /locus_tag="PK063_18715"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3116..3118),aa:Glu,seq:ttc)
BASE COUNT          751 a         1012 c          917 g          539 t
ORIGIN      
        1 tggccggccg gggtggtgag ttcggggtga tcccacacga caacggtcag cacgtcgccc
       61 ggacccactt tatagtcggg cgaggcgggc atggggccaa caccggaacg tccgttcatc
      121 tgggaggcgt tggccgcggg ccgctcggcg gcagcctgct tcatctgctc gatgatcagc
      181 tcggcagtga tcggcttgat ggtgacgttg tcgggcaccg gctcggcggc gggctcctgg
      241 cgcaccggca atttgacggc cgactggtga tcgcgcaggc cgtaggcttt gtcaccgggg
      301 acaagcgcgc aagcccccaa tccagcgcac agcatcacca gcagacatgt tctgatacgc
      361 gtcgttgggt gacaaatagg tgctctcacc ccttcaggtc tgatgttcat gaagtccttg
      421 ataacgtgtg tttgatccgt gcctgaatga tatatgacag tcatgaagct cctaggacac
      481 acgacacact cgggacacaa ttatccgagg gcgggggcct agagccgggc aacccactga
      541 ccgatccctg tgtcgatcag cgcggcggct tcgtcccacg cagcagcgga acggcgatag
      601 ggatcgggga tctcgaactt gccccagtag cccagcagaa aggtcttgcc ccgcacggtc
      661 ggatcgatgt cgccgagggc ctcccggtgg tgcggctcca tcaccagcac cagttcagcc
      721 caccgacaca gggccacgct ggcctgttgc gcacgatggg gtgaaagatc gatgccgagc
      781 gcctgcatgc gctcaatggc ctcgggttcg gcgggctcgc cgacgagggc gcccactccc
      841 gcggaacgga tctcgcccgc cttgcccgct tcagcaagcc ggctgcgcag caggtactcc
      901 cccatggggc tgcgacagat attgcccgtg cacaccacga gtatgcgttg atacaaaacg
      961 gagtcctccc ttcaaccctt gctgatggac agcaggttga cgtctcccgc ttcacagaca
     1021 gtccgaagga gcgcctgagg cttgcgctga gagcgccgat cacggctgcg ccgctcggcg
     1081 ggacggcctt tttcagcgga acggcggtcg ttcccggcgt tccgcgcaac gaattcccgc
     1141 acgaccaagc cttccgagcc ctggaattcg cgcttgaggg tgcccttgat gtggccaatc
     1201 tgcagcggaa tcagtgcctt gtcctcggtg agcagctcca cgacgccaaa actgcgctct
     1261 tcttcggtga tgtcgtccag ctggcgataa accgaaaact ggaaatcata caggttggcg
     1321 aagtctcgct tgagtgcttt ggagaaggtc atcagccccg tttcggtgag cccccccaca
     1381 tagacgccca ccgcctgcac cgaggtgagg cccaacagcc ggtgcacacg gcgcagcgcc
     1441 ggcacaaacc gccaggggcg caggatcacc aggaagcaca gcccgaacaa cacgccaaac
     1501 gcggcgagca tcacgatctc ggagattccg gcatacatgc cggcaagccc gaccgcaccg
     1561 aagaagagct gcaccgacgc caggatgaat accgtgtcct gcacccggaa gccggcgcgc
     1621 tgaaacaggt gatgaagatg gtagcgatcc gcgcggaagg gagagccgcc catccacacc
     1681 cggcgcatca tgacgcataa agtatcaatg aggggtactg caaacaacca cagagtggtc
     1741 acgggggtga tgaccctcac gccctttgtt tcctggcaca ggtcagagag cagccaagca
     1801 aaagcatagc ccagcaccat gctgccgttg tcaccaagga agcagcgtgc ccgacgatgc
     1861 ccaggatagc gcaggttgta gatgagaaaa ccagccacgc caccggcaat gatcatcacc
     1921 agtgagaagt acgcgacatt gcccgaatgg tgaagcgcca gcgcgatgag caccagactg
     1981 accagcgaga tggaaccgga caacccgtcg atgccatcaa tcatgttgag ggcgttgatg
     2041 gcgccgatgg tggcgatcaa cgtcaaggga atccccacat accccagaga caccacgctt
     2101 gcggagccga ggtgcccgaa gtcgcggagc accacacctc ccccgaaaat catgatcacg
     2161 ccgaccatgg cctggatgca caagcggatg cggtagtgca ggttcagcaa atcgtcggca
     2221 aagccggtga tgaacatgat cagcacacca gccgccatag catccaaacg aaagggaaat
     2281 ccgttgctgc ctgaggccac caccccgacg gcacacatga acgcacacac gacaccgatg
     2341 ccacccacga agggcgtcac cgtgtcatgg gccttatgcc cccctggctt atcgacgacc
     2401 ccaaaatggt gtgccgcaac aataccgtag cgtatcgcaa cggccgacac cacggtaccc
     2461 agcaggaaaa gcgccagcga aaacattccc cttcaccccc gcccgttccg gctgtcgccg
     2521 tgcccaggct gcattgattt ccacgccgac acttccggca tccgctccga cgtatcgctg
     2581 tcggcgaccg catcgaattc ggtgcggacg aatcgattaa cattacttca caggaaacat
     2641 tgcttgcaat acatcgcacc gtcccctgct tgccctacta aacagcactg ccctgcccga
     2701 aaaatgcttg aacggctcaa aatgaccgtt caaatggctc atttttgcca aaatcaggct
     2761 ttgaatcaca aaaaccgcca aacatcggac atccggaacg ccactctcga gccgccccaa
     2821 accggcaata agtcacgaag ccgtgcaagt cgctcgaagc cccggatgcc aagacttcct
     2881 cggcgagatc tagcaaattt caggccaaat gaataaaaca aagtttttca aggcgttaaa
     2941 ttttcgcgca agactgccga caggaaagtg taaaatttac cgacagtcga gcgacgtggc
     3001 gcggcaaaat gccacgcaca ggatccgtgc attgcactgc aaaacaggaa aatgagatga
     3061 attcagccgg atcggctggc gtccccacgg ggattcgaac cccggttatc gccgtgaaag
     3121 ggcggtgtcc taggcctcta gacgatgggg accggacgag gattcgcgtc gcgaatcctg
     3181 aaagaaaaag ggagcgaacg ctcccttttt tacagctat
//
LOCUS       DAOQPD010000165         3079 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_23768_length_3079_cov_24.725198, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000165 DAOQPD010000000
VERSION     DAOQPD010000165.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 3079)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3079)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3079
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_23768_length_3079_cov_24.725198"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..763
                     /locus_tag="PK063_18720"
     CDS             <1..763
                     /locus_tag="PK063_18720"
                     /inference="COORDINATES: protein motif:HMM:NF012546.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HMZ99136.1"
                     /translation="MSLLDQFFVYHPHPWEERDWSAVGGVPLEDIWFQAIDGTKLFGW
                     YAENPATSAVLLWCHGNAGNMTHRLENLAALYRLGLSVFLFDYRGYGKSHGRPSEDGL
                     YRDALGAYDYLTKVRRVRPERVVIFGRSLGGAVAGELATQRAAMGLLLESCFPSIEAV
                     ARHHYMGLPMHWLLGAAFRLDNHLPHLSLPKLFVHGDRDDIIPVELGQQAFAAAKAPK
                     EWYVVRGADHNDVPSVGGRAYFAKLFAFIHAAIGR"
     gene            1022..1972
                     /locus_tag="PK063_18725"
     CDS             1022..1972
                     /locus_tag="PK063_18725"
                     /inference="COORDINATES: protein motif:HMM:NF016236.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VacJ family lipoprotein"
                     /protein_id="HMZ99137.1"
                     /translation="MEVVSAVLVLFVVGCAGGPAQTTRQAGSGMESVAQGELRTEGTK
                     PVQVAASPAVSSNMVVLVANKAASPAAEKEPADQPEEDPFFDPFAKSDEPAGGEEYDP
                     WEPVNTKIFEFNRQVDRWVLKPAARGYNAVVPNPVQIGISNLFYNMRFPSRLINNLAQ
                     GKFSGAGTEVGRFLLNSSFGLGGLVDVAKYMDITTPEEDTGQTLGYYGVKPGPYVVLP
                     FLPPFTLRDLVGYVGDIALNPINWLVFPIIEINGVPSLVAHHNRTTSSIAQISGRVEE
                     ILNDRSLNLEKFQGVEEATLDLYTAVKNAYIQKRRNAIRE"
     gene            complement(1976..>3079)
                     /locus_tag="PK063_18730"
     CDS             complement(1976..>3079)
                     /locus_tag="PK063_18730"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HMZ99138.1"
                     /translation="LGPQSSEIRVAQGEVVNLCANNYLGLANHPDVRRAAADGLKDYG
                     YGMASVRFICGTQDLHKRLEQSISTFFGTADTILYSSCFDANGGLFETLLDERDTIIS
                     DALNHASLIDGIRLCKASRLRYAHADMEDLEARLAESSASRVRMIVTDGVFSMDGDLA
                     KLDRIADLADRYDAAVVVDDSHATGVLGKGGRGTPDHFGVAERIDLVTSTLGKALGGA
                     TGGFTTGRKELIELLRQRSRPYLFSNSLPPVIAAAALKAIALVEQGDHLRMNLMEQAG
                     WLRSQLAALGFTLVPGHHPIIPVMLGDASIATKMADRLLQEGIYVVGFSYPVVPKGQA
                     RIRLQLSAAHTRAQLERAVAAFATVGRELHVIN"
BASE COUNT          625 a          858 c          942 g          654 t
ORIGIN      
        1 catgagcctg ctggaccaat tttttgtcta tcacccgcat ccgtgggaag aacgcgactg
       61 gtctgccgtc ggcggggtgc cgttggagga catttggttt caggccatcg atggcacgaa
      121 actcttcggc tggtatgccg agaatcccgc cacctctgcc gtgttgctgt ggtgtcatgg
      181 taatgccggc aatatgaccc atcgattgga gaatcttgcc gcgctctatc gcctgggatt
      241 gtcggtgttt ctattcgact atcgaggtta tggaaaaagc cacgggcgcc cgtcggaaga
      301 cggtctctat cgggatgcac tgggcgccta cgactacctg acgaaagtgc gtcgagtcag
      361 gccggaacgg gtggtcatct tcggacgctc attggggggc gcggtagccg gagagctggc
      421 gacgcaacgc gcggctatgg ggctcttgct ggaatcctgc tttccttcaa tcgaagcggt
      481 tgcgcgtcac cattatatgg ggttgcccat gcattggttg ctgggcgccg ccttccgatt
      541 ggacaaccat ctgccgcatc tttcgttgcc gaagttattt gtgcatggcg accgcgacga
      601 catcattccg gtggaactcg gccaacaggc gttcgccgct gccaaagctc ccaaagagtg
      661 gtatgtggtg cgcggagccg atcacaacga tgtgccgtcg gtcggagggc gagcctattt
      721 tgccaagctg ttcgccttca ttcacgctgc cattggtcgt tgacctggta aaaaatctcc
      781 gcatcttctg tattttttct aggcagattc agctcgcttg gtaagatgcg atggagcggt
      841 caggcataag gccaggagat cggcatcaga gggcgtcctc atctggcagc tgtccgtata
      901 ttctgctaga gtgcgtccgc ctgcgcgccc tgaagacgcg cggtggcaac gttcaatcag
      961 cgtgaaaagc cctcggcgag gaggcaaggt gcatcggaca ggagtgcatg caagaaggtt
     1021 cgtggaggtg gtgtctgcag tgttggtcct cttcgtagtg ggatgtgccg gcggccctgc
     1081 tcaaactacg cgacaggccg gtagtggaat ggaatcggtc gcccaaggag agttacgaac
     1141 cgaagggacg aagccggttc aggtcgccgc gtctccagcg gtctcgtcca acatggttgt
     1201 gttggtggcc aataaggccg cttcgcctgc agccgagaag gaaccggcag accaacctga
     1261 agaggatccg tttttcgacc cctttgccaa gagcgacgag cctgcagggg gtgaagagta
     1321 tgatccttgg gaaccggtga ataccaaaat cttcgagttc aatcggcagg ttgaccggtg
     1381 ggtgctcaag ccggctgcgc gaggatacaa tgcggtggta ccgaacccgg tgcagatcgg
     1441 gatcagcaac ctcttttaca acatgcggtt tccttcccgc ctgatcaaca accttgcgca
     1501 ggggaaattc tccggtgcag gcaccgaggt cggccggttt ctcctgaata gcagcttcgg
     1561 attgggcggg ctggtggatg tggcgaagta tatggatatc accacgccgg aagaagatac
     1621 cggtcagacg ctgggctatt acggggtgaa gccggggccg tacgtcgtat tgccatttct
     1681 gccgccattc acgttgcgcg atctcgttgg ctatgtcgga gacattgcgc tcaatccgat
     1741 caattggctg gtctttccca tcattgaaat aaacggcgtt ccttcgctgg tggcccatca
     1801 caatcggacc acgtcgtcga tcgctcaaat cagcggccgc gtggaagaaa ttctgaatga
     1861 ccgctcgttg aacctggaga agtttcaagg cgtggaggaa gcgactctgg atttgtacac
     1921 agcggtgaaa aacgcctaca tccagaagcg gcgcaacgcc atcagggaat agcgactagt
     1981 tgatgacgtg gagctcgcgc cccacggtgg cgaaggcggc gacggcccgt tcgagttggg
     2041 cgcgggtgtg ggccgcggag agttgcaggc gaatacgcgc ctgtcctttt ggtacgaccg
     2101 gatagctgaa tcccaccaca tagattcctt cctgcagcag gcggtcggcc atttttgtgg
     2161 cgatcgaggc gtctcccagc atgaccggaa tgatgggatg atggcccggt acgagggtga
     2221 agccaagcgc agccagctgg ctccgcagcc agccggcctg ctccatcaag ttcatgcgta
     2281 aatggtcgcc ttgctcgacc aaggcaatag ctttcaacgc ggcggccgcg atgaccggcg
     2341 gcagactgtt cgaaaacaag tagggacgcg accgttgccg taacagctca atcaattcct
     2401 tcctgccggt ggtaaacccg cccgttgcgc caccgagcgc cttgcctagg gtgctggtga
     2461 caaggtcgat ccgctcagca acaccaaaat gatcaggggt gccgcgaccg cctttcccca
     2521 agaccccggt cgcatggctg tcgtccacaa ccacggctgc gtcatagcgg tcggccagat
     2581 cggcaatgcg atccagtttc gccaggtcgc cgtccattga aaataccccg tccgtgacaa
     2641 tcattcgcac ccggctcgca gaggattccg ctagtcgcgc ttccaggtcc tccatgtcgg
     2701 catgggcata gcgcaggcgt gaagccttgc agagacgaat gccgtcgatc aggctggcat
     2761 ggttcagggc atcgctaatg atggtgtccc gctcatcgag caatgtctcg aacaatccgc
     2821 cgttggcgtc gaagcaggag ctgtagagaa tggtgtccgc agtgccgaaa aaggtgctaa
     2881 tgctctgctc gagtcgcttg tgcaagtcct gcgtcccgca aataaaacgc accgaggcca
     2941 taccgtatcc gtagtccttc agcccatccg ccgccgctcg ccgaacatca ggatggttgg
     3001 ccagcccaag atagttattc gcacagaggt tgacgacctc accctgggca acgcggatct
     3061 cgctgctttg cggacctaa
//
LOCUS       DAOQPD010000166         3064 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_23942_length_3064_cov_20.454304, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000166 DAOQPD010000000
VERSION     DAOQPD010000166.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 3064)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3064)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3064
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_23942_length_3064_cov_20.454304"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..419)
                     /locus_tag="PK063_18735"
     CDS             complement(<1..419)
                     /locus_tag="PK063_18735"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99139.1"
                     /translation="MKVPGKNVMLGGLMGLWATVAAVQVSSLPELREVPLTYTTGQRV
                     AKGATPTITVDALELRPMRMVAAHLPSTPTRNIFEAAETPTSEKRLVRAAVNKKEVPL
                     PIPVPVVAMPLVPPAPPMPSPEEVAEQAARLARERAR"
     gene            complement(416..1024)
                     /gene="pilO"
                     /locus_tag="PK063_18740"
     CDS             complement(416..1024)
                     /gene="pilO"
                     /locus_tag="PK063_18740"
                     /inference="COORDINATES: protein motif:HMM:NF016253.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0043107 - type IV pilus-dependent motility
                     [Evidence IEA];
                     GO_process: GO:0043683 - type IV pilus assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HMZ99140.1"
                     /translation="MANLFKHVQWSGMSRSLLLSCVPLMSITVLACVLAATNYFYRLS
                     PAQEHLAQAEAAYQTTLRAQAALQATRKTQEEILAIKLKLDEVWRGLPTETEFASLAL
                     AISELGRSERVTIPGMQYAVERSPADGLPVKASISFSVTGEYAAVYRFIHRLESADSY
                     VVIESLNASRTAKSDKGAASAVVFHVTIATFLRPNPPTGSLS"
     gene            complement(1034..1693)
                     /locus_tag="PK063_18745"
     CDS             complement(1034..1693)
                     /locus_tag="PK063_18745"
                     /inference="COORDINATES: protein motif:HMM:NF016992.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HMZ99141.1"
                     /translation="MGLAWIPFLRSPRAVSPVPHIAFSVTPTAITILRVMQWMAVVLC
                     CVSLAVALTWWNDSVVMEETATHLDGVVRRLNQANTNRAERMTRERLTLSADQIAAIT
                     RDVRFVNQLAEKRAFSWSRLLADLESTLPPHMALRTVQLNFQDSTVALHGSAASLQDI
                     RTFMTNLEHHTAFRHAALASHRLEHQERQPSQASMAVPDTMQSARGVDFQLTVGYRPS
                     W"
     gene            complement(1705..2655)
                     /locus_tag="PK063_18750"
     CDS             complement(1705..2655)
                     /locus_tag="PK063_18750"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99142.1"
                     /translation="MRPTLVPIHRPRVGISVSASALSLVALRRPWFRRPIVKQVVERP
                     LPSGLLKVSATEPHITDLDAFAQELRALTEGLSERTVALSVPNRAMHMGVFAFNRFPD
                     DPEERAGLIKWRFREDLNLAIGDARVMMQVFAAGTRTQVLAVAVRQTILDQYEDVCGR
                     AGLIPVSMGFSHLQLIGLYRRLMKGTRRLCVMHWAGDEFMLLLFDQGQPVFLRTRSMT
                     SGTQDLRRELVGTLQYMADQATTVHETGESSFPLYLIGGQSNASITQLLGGEATVTVP
                     GYRGGWQLEVVPLGWDSLPAHLNNQTGSLNGLSAMATVVG"
     gene            complement(2660..>3064)
                     /locus_tag="PK063_18755"
     CDS             complement(2660..>3064)
                     /locus_tag="PK063_18755"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilB"
                     /protein_id="HMZ99143.1"
                     /translation="MGIEPYNFVSSLNCIMAQRLVRTICESCKAPHTVSQAQCEQLGF
                     DYELFKDRPVYEGKGCLDCHGLGYRGRHAITEFLPLTDRIRELMLDRRPPSEIRRAAV
                     EQGMTDLRQAGVEKVRRGETTMREVNRMTFLG"
BASE COUNT          634 a          988 c          854 g          588 t
ORIGIN      
        1 tgccgggcgc gctcccgcgc cagtcgcgcg gcctgttcgg ccacttcttc cggagagggc
       61 atcggtggcg cgggcggaac cagcggcatc gcgaccaccg gcaccgggat cggaagtggc
      121 acctctttct tgttcaccgc tgccctgacg aggcgctttt cggatgtcgg tgtctcggct
      181 gcttcgaaaa tgttgcgtgt cggcgtcgac ggcaagtgcg ccgccaccat ccgcatcgga
      241 cgtaactcca gggcatcaac cgtgatcgtc ggtgttgccc ccttcgccac acgctgacca
      301 gtcgtatagg tcagtggcac ctccctcaac tccggcagac tgctgacctg caccgcggcc
      361 accgtcgccc acagtcccat cagtccaccc agcatcacgt tcttgcccgg aactttcatg
      421 acagactccc cgtcggtgga ttcggtcgca aaaacgtcgc gatcgtgaca tgaaacacca
      481 cggccgatgc cgcccccttg tcactcttcg ccgttcggct cgcgttgaga ctctcgatga
      541 ccacataaga atcagccgat tccaatcggt gaatgaagcg atagaccgcc gcatactcgc
      601 cggtcacgga aaacgagatc gacgccttca ccggaaggcc atcggcgggc gatcgctcga
      661 ccgcatattg cattccggga atggtcactc gctcgctgcg tcccagttca gaaatggcga
      721 gcgccagtga ggcaaactcc gtctcggtcg gaaggccccg ccagacctcg tcgagtttca
      781 gcttgatcgc taggatctcc tcctgtgtct tgcgtgtggc ctgcagtgcg gcctgcgccc
      841 gcaaggtggt ctgataggcc gcttcggcct gagcaagatg ctcctgcgca gggctcaatc
      901 tgtaaaaata gtttgtcgcg gcaagcacac aagccaatac cgtgatactc atgagtggta
      961 cgcaggatag gagaagcgat cggctcatcc ccgaccactg cacgtgtttg aacaagttcg
     1021 ccataccttc ctcttaccac gacggtcggt agccgacggt caactgaaag tctacgcctc
     1081 gtgcagattg catagtatct ggcacagcca tgctcgcctg cgacggctgc cgctcctgat
     1141 gctcaagacg atgactggct aacgccgcat gccggaacgc cgtatggtgt tccaaattcg
     1201 tcatgaacgt acggatgtct tgcagcgacg ccgccgatcc gtgaagcgcc acggtcgagt
     1261 cctgaaagtt caattgaacg gtacgaaggg ccatatgtgg aggaagagtg ctctccaagt
     1321 ctgccaacaa acgggaccag gagaacgccc gcttctcggc gagctgattg acgaagcgca
     1381 catcgcgcgt gatggccgcg atctgatccg cggacaacgt cagtcgctca cgggtcatgc
     1441 gctctgcacg gttggtattg gcctgattca accgccgcac caccccatcg aggtgcgtgg
     1501 cggtttcctc catcaccaca ctgtcattcc accacgtcaa cgccactgcc aatgagacac
     1561 aacacagaac gaccgccatc cactgcatga cacgcaggat ggtaatggca gtcggcgtga
     1621 ccgagaatgc gatgtgaggc acggggctga ccgcacgcgg cgagcgcagg aatggaatcc
     1681 acgctaggcc catcggattt ctcatcatcc gaccaccgtc gccatcgctg agagcccgtt
     1741 taacgatccc gtctggttgt tgagatgggc cggaagactg tcccatccca atggcacgac
     1801 ctcgagctgc catccacctc gatagccagg caccgtcacc gtcgcctccc ctccgagcag
     1861 ctgcgtgatc gatgcgttcg actgaccacc gatcaggtac aagggaaacg aggactcacc
     1921 cgtttcatgc acagtcgtcg cctggtcggc catatattgt agggttccga ccagttcgcg
     1981 tcgaagatcc tgcgtcccgc tggtcatgga tctggtgcga agaaacactg gttgcccctg
     2041 atcgaacagc agcagcatga actcatcccc tgcccagtgc atcacgcaca gccgtcgagt
     2101 gcccttcatc agacgacgat agaggccgat gagttggagg tgcgagaatc ccattgagac
     2161 agggatgagc ccagcccgtc cgcagacgtc ctcatattgg tccagaattg tctgacgcac
     2221 cgccacagcc agcacctggg tgcgtgtccc ggcggcgaag acctgcatca tcacccgagc
     2281 gtcgccaatc gccaggttga ggtcctcacg gaaccgccac ttgatcagac ctgctcgttc
     2341 ttcgggatca tcagggaatc gattgaatgc aaacaccccc atgtgcatcg cgcgattggg
     2401 cacactcagc gcgaccgttc gctcgctgag cccttcggtc aacgcccgca gctcctgcgc
     2461 gaaggcatcc agatcggtga tgtgcggctc cgttgcggag accttcagca agccactggg
     2521 caacggacgc tccactacct gtttcacgat tggcctgcgg aaccacggcc ggcgcagagc
     2581 caccagactc agtgcggaag ccgacacgct gatgccgaca cggggacgat ggatgggaac
     2641 gagtgtgggc ctcatacggc tatcccaaaa atgtcatccg attgacttcg cgcatcgtgg
     2701 tctcccctcg tcgtaccttc tccacgccgg cttgacgcaa atcggtcatc ccctgttcga
     2761 ccgccgcgcg cctgatctca gacggcggcc gccgatctaa catcaactcc cgaatccgat
     2821 cggtgagcgg cagaaactct gtaatggcat ggcgcccgcg ataccccaat ccatgacagt
     2881 ccaggcaccc tttgccttca tacacgggac ggtccttgaa gagctcgtaa tcaaacccca
     2941 gttgttcaca ctgagcttga gacacggtgt gcggggcctt acaggattca cagatggtgc
     3001 ggaccagacg ttgggccatg atgcagttca gagacgagac gaagttatag ggctcgatcc
     3061 ccat
//
LOCUS       DAOQPD010000167         2999 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_24881_length_2999_cov_21.989810, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000167 DAOQPD010000000
VERSION     DAOQPD010000167.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 2999)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2999)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2999
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_24881_length_2999_cov_21.989810"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..581)
                     /locus_tag="PK063_18760"
     CDS             complement(<1..581)
                     /locus_tag="PK063_18760"
                     /inference="COORDINATES: protein motif:HMM:NF012515.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="HMZ99144.1"
                     /translation="MDHAGLGAYIQRFSRASVLVIGDLILDHYVWGRVSRISPEAPVP
                     VVHVESESLKLGGAANVFNNILALGGQADICGVIGADESGRLLLKELGGRRQGRGGVV
                     IDQSRPTTRKSRVVAHNQQIVRYDVERRNELSSLLQRRILRYVESRLKELSCLVVSDY
                     AKGVVTASLMTELTRLAGQRKIPIVVDPKVEHF"
     gene            complement(635..1414)
                     /gene="lepB"
                     /locus_tag="PK063_18765"
     CDS             complement(635..1414)
                     /gene="lepB"
                     /locus_tag="PK063_18765"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HMZ99145.1"
                     /translation="MSVDPNARPEEIPATNAPAPPPTPPEPATTEPRLVVANQPAHKS
                     ILREYAEAIIIAMLLAFAIRVFVVQAFKIPSGSMIPTLLVGDHILVSKLSYGLQWPTD
                     CKFQPGFPPVTCYSSHTVIPFGSIQRGDIIVFRFPEDEDKDFIKRVIGLPGDTIHVRN
                     KVVHINGTPFDDHAFTQHTDPPIHDGHISPRDNFGPVTVPEDAYFVMGDNRDHSLDSR
                     FWGYVRTEKVRGKAFRIYWSWSGQGSWTEWVRWERLGKAIQ"
     gene            complement(1411..>2999)
                     /gene="lepA"
                     /locus_tag="PK063_18770"
     CDS             complement(1411..>2999)
                     /gene="lepA"
                     /locus_tag="PK063_18770"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HMZ99146.1"
                     /translation="YLLHLIDTPGHVDFTYEVSRSLAACEGSLLLVDATQGVQAQTIA
                     NVNLAMGNHHTIIPVINKIDLASADVEGTKQQISDVLTLDATDSMLVSAKEGLGVPEV
                     LEAIVKRIPPPSGDPTRPLKALIFDSWFDNYQGVIVLTRIIDGSVRPGMKIKVMSNDR
                     LFEVTEVGQFTPKRTKGTQLLTGEVGYLCANMKEVADVKIGDTLTDAARPTDQPFPGY
                     KEVKPLVFCGLYSTDTARYEDLRDALLKLRLNDSSFIYEPETSLALGFGFRCGFLGLL
                     HMEIIQERLEREYGLTLITTAPTVIYRILTTKGDVLELNNPAELPEPSSIASFEEPFI
                     LATLIAPERYLGTLLQLCQERRGIQRSIHYLDPTRVVIAYELPLNEVILDFYDKLKSK
                     TQGYASLDYELLGYRESELVRLDILLNGEPVDALSFITHKERAYQRGRQVAEKMKELI
                     PKQMFEIAIQAAIGNKIIARETIGAIKKNVTAKCYGGDISRKRKLWDKQKEGKKRMKA
                     VGRVEVPQEAFLAILKVGEE"
BASE COUNT          577 a          866 c          893 g          663 t
ORIGIN      
        1 ctgaaatgct ccaccttggg atcgacgaca atggggatct tgcgctgtcc cgccaaacga
       61 gtcaactctg tcatcagcga ggccgtgacg acgcccttgg catagtcgga gaccaccaga
      121 caggagagtt ccttcaggcg tgattccacg taccggagaa tacgccgctg caggaggctg
      181 gagagttcgt tgcggcgttc gacgtcatag cgaacgattt gctgattgtg ggcgacgacg
      241 cgtgattttc tggtcgtcgg ccggctttga tcgatgacga ctccgccccg tccctgcctg
      301 cgcccgccca attctttcag gaggagccgt ccgctttcgt ccgccccgat gactccgcag
      361 atatccgcct ggccaccgag tgccagaatg ttgttgaaga cgttcgccgc gccgccgagc
      421 ttcagtgatt ccgattcgac atgcaccacc ggcaccggag cttccggaga gatccggctg
      481 acccggcccc agacgtagtg atccaggatc aaatccccga tgaccagcac actggcccgg
      541 gaaaatcgct ggatgtacgc gccgagtcca gcgtgatcca tcgccgcctc ttctgccgcg
      601 tgcccgttcg acggtccggc atggccggat cgccctactg gatggctttt cctaaccttt
      661 cccatcgtac ccattccgtc cacgatcctt ggccgctcca cgaccagtaa atgcgaaatg
      721 ctttgccgcg cactttctcc gtgcgcacgt atccccagaa ccgactgtcg agactgtgat
      781 cccggttgtc ccccatcacg aagtaggcat cctccggcac cgtcaccggg ccgaaattgt
      841 ctcgcggact gatgtgcccg tcgtgaatgg gcggatcggt gtgctgcgtg aaggcatggt
      901 catcgaacgg ggttccgttg atgtgcacca ccttgttgcg tacgtggatg gtgtcacccg
      961 gcagcccgat cacacgcttg atgaagtcct tgtcttcgtc ctcggggaac cgaaacacga
     1021 tgatgtcgcc gcgttgaatc gatccgaacg gaatgaccgt gtgcgaggaa tagcaggtga
     1081 ctggtggaaa gcccggttga aacttgcagt ccgtcggcca ctggagaccg taggataatt
     1141 tgctgacgag gatatggtct cccaccagaa gcgtgggaat catcgagccg gatggaattt
     1201 tgaaggcctg caccacgaag acacggatgg cgaacgcgag caacatggca atgatgatgg
     1261 cttccgcata ttcgcgcagg atcgacttgt gggccggctg gttggccacg accaggcgtg
     1321 gttcggtggt cgccggttcg ggaggcgtgg gtgggggcgc cggtgcattc gtcgcaggga
     1381 tttcctccgg acgggcattg gggtccacgc tcattcctcg cccaccttga gaatggccag
     1441 gaacgcttcc tgcggcactt ccacgcgtcc caccgctttc atgcgcttct tgccttcctt
     1501 ctgcttgtcc cacagcttgc gcttgcggga aatgtcaccg ccgtagcatt tggccgtgac
     1561 atttttcttg atggcgccga tggtttcacg cgcaatgatc ttgttgccga tggccgcttg
     1621 aatggcaatt tcaaacatct gtttgggaat gagctctttc attttttcgg cgacctggcg
     1681 accgcgctga taggcccgtt ccttatgggt aatgaacgag agcgcgtcga ccggctcgcc
     1741 gttgagcaga atgtccaagc gcaccagttc cgactcgcgg tagccgagca gctcataatc
     1801 gagcgacgca taaccctggg ttttcgactt gagcttgtcg taaaaatcga gaatgacttc
     1861 gttgagcggc aattcatagg cgatgaccac gcgggtcgga tccagatagt gaatgctccg
     1921 ttgaatgccg cggcgttcct ggcacaattg cagcaacgtg ccgaggtacc gttccggcgc
     1981 gatcagcgtg gccagaataa acggttcttc gaaggaggcg atcgaactcg gttcaggcaa
     2041 ttccgcaggg ttgttcagtt cgaggacatc ccctttggtg gtgaggatcc gatagatgac
     2101 ggtcggtgcg gtggtgatca gggtcagccc gtattcccgc tccagtcgct cctgaatgat
     2161 ttccatatgg agcaggccca ggaatccgca gcggaatccg aatcccagcg ccagcgaggt
     2221 ttccggctcg taaatgaagg acgagtcgtt caggcgcaac tttaaaagcg catcacgcaa
     2281 atcttcgtag cgcgcggtgt ccgtcgaata gaggccgcaa aaaaccagcg gtttgacttc
     2341 cttgtacccg gggaacggct gatcggtcgg ccgtgccgca tcggttaagg tgtccccgat
     2401 cttcacgtcg gctacttcct tcatgttggc gcagagatat ccgacctctc ccgtcaggag
     2461 ttgcgtgccc ttcgttcgct tgggggtgaa ctgcccgact tccgtcactt cgaacaaccg
     2521 gtcgttcgac atgaccttga tcttcatgcc cgggcgaacg gacccgtcga tgatgcgggt
     2581 caggacgatc acgccttggt aattgtcgaa ccaggaatcg aaaatcagcg ccttgagcgg
     2641 acgagtcgga tcaccggacg ggggtggaat gcgtttgacg atcgcctcga ggacctccgg
     2701 aacgccgagc ccttcctttg cgctcacgag catggagtcc gtggcatcca atgtcagcac
     2761 gtcggagatc tgttgtttgg taccttcgac gtcggcgctg gcaagatcga tcttgttgat
     2821 gaccggaatg atggtgtgat ggttgcccat cgccaggttc acgttggcaa tggtctgggc
     2881 ctggacgcct tgtgtcgcat cgacgagcag cagcgatccc tcgcaggccg caagactgcg
     2941 tgatacttcg tacgtgaagt cgacgtgccc cggcgtatcg atcaaatgca gtaaatagg
//
LOCUS       DAOQPD010000168         2955 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_25551_length_2955_cov_24.677586, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000168 DAOQPD010000000
VERSION     DAOQPD010000168.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 2955)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2955)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2955
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_25551_length_2955_cov_24.677586"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..787)
                     /locus_tag="PK063_18775"
     CDS             complement(<1..787)
                     /locus_tag="PK063_18775"
                     /inference="COORDINATES: protein motif:HMM:NF019335.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor plug domain-containing
                     protein"
                     /protein_id="HMZ99147.1"
                     /translation="MARRIGVMGGGAVCVLVMGLVCGVSVHARAEGTEAAVPGQDASA
                     AKSNEEASGVVAESGETPKPKPVKIPEVMVRDVHERNEPDQESVKDIAGSVNVVTREE
                     IQRARPKNADEMLRRVPGVNVLDEYGQGLRPNIGIRGMDPRRSKNILLMMDDIPIQPA
                     LFGDASTYYMVPIERIDHIEVIKGGASVLYSPNTQGGLINFIQKRIPMTPTFSTTNTY
                     GSFNLFQSDTQYGGYWGNFGAQLGYLRRQSDGFRDRSKSQLDDF"
     gene            complement(929..1117)
                     /locus_tag="PK063_18780"
     CDS             complement(929..1117)
                     /locus_tag="PK063_18780"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99148.1"
                     /translation="MTNSTKREPARMLTCDDVRCRCGQLVARWAEEGIEIKCKRCRRL
                     VTIAFGSIAGRPPAMLEN"
     gene            complement(1174..1632)
                     /locus_tag="PK063_18785"
     CDS             complement(1174..1632)
                     /locus_tag="PK063_18785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013247225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99149.1"
                     /translation="MKDVMQRVRRGLSSAVLCSVCLLWLGTGTALAESKGEKAFQAVA
                     TDAKGVETDVHGIIFYWEEKISETSFVPHELKEVPVKRGTATVKIKFDVIKAIDVKPS
                     GNGAPPAVSITLNDGKTGEFTLAIAGSFKGQSDFGEVELPAVELKRIAFK"
     gene            complement(1672..2715)
                     /locus_tag="PK063_18790"
     CDS             complement(1672..2715)
                     /locus_tag="PK063_18790"
                     /inference="COORDINATES: protein motif:HMM:TIGR01352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015291 - secondary active transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB family protein"
                     /protein_id="HMZ99150.1"
                     /translation="MSDIALRAHIVYERGSRSGGWLISLLLHGGLVALAMQAVMEVTP
                     HRQTETFRWDVALQSAPAPSPLAAEPLPPQQSVPQPPQPQKPVSRPVSQPSPEPVSQV
                     VERTAVVQTVQATQVTPRVVERSAPQERQAVATEVQPVTSQPVHETMVAHAQEILPQE
                     RQETVHTVEAQAVVTQVSEAMIQESAVPVATQSTAVEQPPIVEPAVVATEAPVETSAA
                     PVIEPQEAIVSEPVVVRQSAVVHREVREQAPAQADLGWLAESLWSRIEELKRYPRQAR
                     ARRWEGKVVLEAVIRHDGTILECLIAESSGHGLLDQDAISVLRKASPLTLKHPLGKEQ
                     ITILVPIAYRLES"
BASE COUNT          602 a          945 c          746 g          662 t
ORIGIN      
        1 tgaaatcatc taactgcgat ttgcttcgat ctcgaaatcc gtctgactgg cgccggagat
       61 acccgagctg cgcgccaaaa ttcccccaat agcccccgta ctgagtgtcc gattgaaata
      121 ggttgaaact gccgtacgta ttggtggtag aaaacgtcgg tgtcatggga atccgcttct
      181 ggatgaaatt aatcaggcct ccctgcgtgt tcggtgaata gagcacggac gcgccgcctt
      241 tgatcacctc gatatggtcg atacgttcga tcggcaccat gtaatacgtc gaggcatcac
      301 caaagagagc cggctggatg ggaatatcgt ccatcatcag cagaatattt ttgctgcgcc
      361 gaggatccat cccccggata ccgatgttcg gccgcaaccc ctggccatat tcgtccaaca
      421 cgttcacacc gggcacgcgt cgcaacatct cgtctgcgtt tttcggccgg gcccgctgaa
      481 tttcctcgcg cgtgacgaca ttgaccgacc ccgcgatgtc cttcaccgac tcttgatccg
      541 gctcgtttcg ttcatggaca tctctcacca tcacttcggg aatcttcacc ggcttaggtt
      601 tcggcgtttc ccccgattca gccacaacgc ctgaggcctc ttcattggac ttggcagcag
      661 aggcatcctg accaggcaca gccgcctctg ttccttcggc ccgcgcatgg acactcacgc
      721 cgcagacaag tcccataacc aacacacata ccgcccctcc gcccatgacc ccgatacgtc
      781 tcgccatgat tacttgttct ccttgttcat tcaccgacac gtagaaagac atcagcacac
      841 ataaaaaagc ccaagaccct gttgatggtc ttgggctctg gacacacacg gtcctttggc
      901 ctctatggca tgatcggctg aggatggatt aattctcgag catcgccggc ggcctccccg
      961 cgatcgaccc aaaagcaatg gtgaccagac gccggcaccg cttgcatttg atttcaatgc
     1021 cctcttccgc ccaacgagcc accagctgtc cgcaccggca ccgcacatcg tcgcacgtca
     1081 acatccgggc aggttcacgc ttcgtgctgt tcgtcatgcc aattcctcca ctcgacggcc
     1141 ttctgttccg tcacgctcaa ttcgccgccg catttattta aaggcgattc gtttgagttc
     1201 gaccgccggc aattcgactt cgccaaaatc cgattgcccc ttaaagctgc cggcgatcgc
     1261 cagggtgaac tcgccggtct tgccgtcgtt caacgtaatc gagacagccg gcggcgcccc
     1321 gtttccggac ggtttcacat cgatggcctt gatcacatcg aacttgattt tgactgtggc
     1381 cgttccgcgc ttcaccggca cttccttcag ttcgtgcggc acaaacgagg tttcgctgat
     1441 cttctcttcc caataaaaaa taatgccgtg cacatcggtc tccacccctt tggcatcagt
     1501 cgccaccgcc tgaaacgctt tctcgccttt cgactcagca agagctgtcc cagtccccag
     1561 ccataacagg catacgctgc acaggacagc gctcgacaac cccctccgca ctctctgcat
     1621 gacatccttc atggtgaaac tcctttgccc cttgtgatga tgttgctgtt actaactttc
     1681 aagccgatag gcaatcggca cgagaatggt gatttgctct ttccccagcg gatgtttcaa
     1741 ggtgagggga gacgccttcc gcaacaccga gatggcatcc tgatccagca acccgtgacc
     1801 ggaactttcg gcaatcaaac attccagaat tgttccgtca tggcggatca ccgcctccag
     1861 cacgaccttg ccctcccacc ggcgtgcccg cgcctgccgg ggatatcgct ttaattcttc
     1921 aatcctggac cacagcgact ccgctaacca gccaaggtct gcctgcgccg gagcctgttc
     1981 acgcacttcg cgatgcacga ctgcgctttg acgcacgacg accggctccg atacgatcgc
     2041 ctcctgcggc tcgataacgg gagccgctga ggtctccaca ggtgcttcag tcgcaacgac
     2101 cgctggctcg acgataggcg gctgttccac tgcagtcgac tgcgttgcga caggaaccgc
     2161 cgactcttga atcatcgcct cggatacctg cgtcaccacg gcctgtgctt cgacggtatg
     2221 aacagtctcc tgacgttctt ggggaaggat ttcttgcgca tgcgccacca tggtttcatg
     2281 taccggttgc gaggtgacag gctgtacctc tgtcgcgacc gcctgacgtt cctgaggagc
     2341 ggagcgttcg actactcgcg gggtgacttg cgtagcctga accgtttgaa cgactgccgt
     2401 ccgctccacg acctgagata ctggctccgg tgaaggctgc gacaccggcc gagacacggg
     2461 cttttggggc tgtggcggtt gcggaacgga ctgttgcgga gggaggggct cagctgctaa
     2521 aggactcggc gctggggccg actgcaaggc gacatcccat cgaaaggtct cggtttgccg
     2581 atggggtgtg acctccatca ccgcctgcat cgcgagggcg acaagtccgc catgcaacag
     2641 caatgagatc agccatccac cgctacgaga tccccgctcg tatacgatat gggctctgag
     2701 tgcgatgtct gacatgctcc gacctcctcc ccgaccagac aatccggtcc gcgggacagt
     2761 aaataaaaaa agcccaaagc tgtcgtgata cagctttggg ctctgaccgc aggggtcgct
     2821 ggccttattc gagtgttgcg cgaacgtgac gcactacccg cgtccttgac caagatttag
     2881 tcggcttttc tcccgacaag tcttgatagc aattctcaat atcatgaccg cgaaacagtt
     2941 gtcaatgcgc atatc
//
LOCUS       DAOQPD010000169         2869 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_26964_length_2869_cov_18.503909, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000169 DAOQPD010000000
VERSION     DAOQPD010000169.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 2869)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2869)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2869
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_26964_length_2869_cov_18.503909"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(139..642)
                     /locus_tag="PK063_18795"
     CDS             complement(139..642)
                     /locus_tag="PK063_18795"
                     /inference="COORDINATES: protein motif:HMM:NF015935.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HMZ99151.1"
                     /translation="MSVDSSLGSSNGGRPLSPVRKYAVPRYRVTLVREGRALPAAESV
                     HTSDGAVAILRPLFAGLDREQFLICGLDAKHKLIGINVVSTGSLNLTIVHPREVFKPL
                     ILMNAGAWICAHNHPSSDITPSPEDRALTKRLREAADLFGIPLLDHLILAEERYYSFA
                     DQGWPGA"
     gene            1061..1198
                     /locus_tag="PK063_18800"
     CDS             1061..1198
                     /locus_tag="PK063_18800"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99152.1"
                     /translation="MAKTHAKYGQKWPLTDNHQSAMTLAGLELQSLEFEKNEDVSEPK
                     E"
     gene            1203..2837
                     /locus_tag="PK063_18805"
     CDS             1203..2837
                     /locus_tag="PK063_18805"
                     /inference="COORDINATES: protein motif:HMM:NF012464.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HMZ99153.1"
                     /translation="MIAAIYARKSTEQSGVIEEEKSVTRQIEHAKAYAASKGWNVSEE
                     HIFVDDGVSGAEFVKRPGFIRLMNALKPRPTFHLLIMSEESRLGRESIETSYALKQIM
                     DAGIRVFFYLEDRERTLDNALDKVLLSLTNFASEMERERAKQRTYDAMLRKAKAGHVT
                     GGKVFGYDNREILSAEGRRLHVLRVINAAEAAVVRQIFEMFAGGVGIGRITKRLNEEC
                     TPAPRQSPRGWAPTAVREIIRRPLYKGEIVWNQHEKIVRGGTKKRRERNEKDWIRLDA
                     PDLRIISPELWDSVAKRLEKRKGQRRSAFRDVESKYLLTGMARCAHCGGPMTIVGQDY
                     HREKGRFYGCSYYKSRGSSICKNSLLVEQELLDQTVLKAIEEALTEEMLKVAIEKALT
                     KHRAGASVQLDHRSRIERELSLIEAQLKNLVDAVANGRKESALFERLANEEERKRSLI
                     ADLERLTRPEHVPHLDEARLKRELKARFADTRALLGRHITSARRLLRVLMERPLRLET
                     MQDGDRKGYRVTGTGSYLPLLSETRHSVESGVPNGI"
BASE COUNT          675 a          750 c          885 g          559 t
ORIGIN      
        1 aaggagttcc aacatgacgg cgcaacagat tcaaaccatt ggcaatgcgc tggctatcga
       61 tctggtcgcc tgggggacgg cggcgatcgg gctggcgttg gtggctgccg gggccgcttg
      121 ggtgttgcgg ctgctccgct aagcgccggg ccagccttgg tcggcgaagc tgtagtagcg
      181 ttcttcggcg aggatgagat gatccaacag cggaattccg aagagatcag ctgcctcgcg
      241 cagccgcttg gtcagggcgc ggtcttcggg gctcggcgtg atgtcactgg aggggtgatt
      301 gtgggcgcag atccaggcac cggcattcat caggattagc ggcttgaaga cctcgcgagg
      361 atgaacaatg gtcagattga gggagcctgt ggagacgaca ttgatcccga tgagcttgtg
      421 cttggcgtcc aggccgcaga ttaagaattg ctcccggtcc agaccggcaa acaacggccg
      481 gaggatggcg accgcaccat ccgacgtatg gaccgattcc gccgccggaa gggcacggcc
      541 ctcacgcacg agcgtgacac ggtaccgagg gaccgcgtat ttccgaaccg ggctcagtgg
      601 ccgtccaccg ttcgaggaac cgagagaact gtcaacggac atgtccgcct ccttctgaaa
      661 ttatgttcta gccccaccct tcaccaacca agggtggggc gtaacgaagg aggcggcacg
      721 gggctctcgc agcgggcagg cctggagggg cggagaccgg cacggagggg accgggaagg
      781 cctgctccgc tgctccccgg ccccgggccg tatccactgg gggctcactc ttcgacccaa
      841 cctgcggaag acggggcgct tccgcgtagt gagagagggg ctttggatca cttgaggaga
      901 agctattcag atggaacggg caaaacctaa gctactcaac agagtgagta attctcggcc
      961 caaaaggacc acctctcccc tcccgagtca catccgagat gaaatttcat caattcttgc
     1021 cgatgcgctg cttgcggatc ttcaagcaga tagcagacct atggccaaaa cccatgcgaa
     1081 gtacggacaa aaatggccat tgactgataa tcaccagagc gctatgacgc ttgcaggatt
     1141 ggagttacag tccctggaat tcgaaaagaa cgaagacgtg tcggaaccga aggagtagcc
     1201 cagtgattgc agccatatac gcacggaagt ccactgaaca atctggagtg attgaggagg
     1261 agaaatccgt cacccggcag attgaacacg caaaggcgta cgctgcgagc aaggggtgga
     1321 atgtctctga ggagcatatc ttcgtggatg acggtgtttc cggggcggag tttgtgaagc
     1381 gaccggggtt cattcggctc atgaatgctc tcaaacctcg tcccaccttc catctgctga
     1441 tcatgtccga ggagtctcgg ctggggcggg aatccattga aacatcttat gccctgaagc
     1501 aaattatgga cgcaggaata cgagtcttct tctatctgga agatcgtgag cgtaccctcg
     1561 acaacgccct cgacaaggtg ctgctctcac ttactaattt cgcgtctgaa atggagcgtg
     1621 agcgcgctaa acagaggacc tatgacgcga tgctccggaa agcaaaggcc ggacatgtca
     1681 ctggcgggaa ggtctttgga tacgataatc gggagattct ttctgccgag gggcgaagac
     1741 ttcatgtgct tcgcgtgatc aatgcggctg aggccgccgt tgtccgccag atcttcgaga
     1801 tgtttgcagg cggcgtcggg atcggccgta tcaccaaacg actcaatgag gaatgtactc
     1861 ccgcgccacg ccagagtccg cggggctggg cgcccactgc cgtgagagaa attatacgcc
     1921 gaccactgta caagggagaa attgtctgga accaacacga aaaaatcgtg cgaggaggta
     1981 ccaagaagcg gcgggaacgc aatgaaaaag attggattcg cttagatgct cccgatttga
     2041 ggatcatttc tcccgaactg tgggactccg tggcaaaacg gctggagaaa aggaaagggc
     2101 aacgacgctc ggccttccgt gatgtcgagt cgaagtatct tctcacggga atggcacgct
     2161 gcgcccattg tgggggaccc atgacgatcg tagggcagga ttatcaccgg gaaaagggac
     2221 gcttctatgg gtgcagctat tacaagtctc gcggctcgtc gatttgtaag aattccttgc
     2281 tcgtggaaca agaactactt gaccaaacag tcctaaaggc tatcgaggag gcgctgaccg
     2341 aggaaatgct aaaagtcgcc atcgaaaagg cattgactaa acacagagcc ggggcgagcg
     2401 tgcagcttga tcatcgctct aggattgagc gcgaattgtc cctaattgag gctcagttga
     2461 agaatttggt cgacgccgtc gctaacggtc gaaaggagag tgcgctgttt gagcggctcg
     2521 ccaacgagga agagcgaaaa cgctccctga tcgcggacct ggaacgactc acgcggcctg
     2581 aacatgtccc ccatctcgat gaggctcgcc tcaaacgtga actgaaagcg cggttcgcag
     2641 atacgcgagc gctcctaggg cgccacatta cttctgccag acgactgctt cgggtcttga
     2701 tggaacgccc attacgcttg gagaccatgc aggatgggga tcgaaagggg tatcgcgtga
     2761 ctgggactgg cagctatttg ccactgctgt ctgaaacgag gcactccgtg gaaagtggtg
     2821 tccccaacgg gatttgaacc cgtgttactg ccttgaaagg gcaatgtcc
//
LOCUS       DAOQPD010000170         2826 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_27712_length_2826_cov_26.783472, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000170 DAOQPD010000000
VERSION     DAOQPD010000170.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 2826)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2826)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2826
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_27712_length_2826_cov_26.783472"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..455
                     /locus_tag="PK063_18810"
     CDS             <1..455
                     /locus_tag="PK063_18810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional repressor KorB C-terminal
                     beta-barrel domain-containing protein"
                     /protein_id="HMZ99154.1"
                     /translation="FNSGRCRDVTVINELVTAHKKARNEVGLWLADDTQEITRGSVKL
                     LREYLDDKRQHEHDEGNSDTVESTASARTVAGEGEEATHSRRESKAVDPDRLRRAIVH
                     VQHDGRPARLILNRRPPLEGHAWLKYDDDGHELAADLAQVQLVALLEG"
     gene            608..1450
                     /locus_tag="PK063_18815"
     CDS             608..1450
                     /locus_tag="PK063_18815"
                     /inference="COORDINATES: protein motif:HMM:NF023168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HMZ99155.1"
                     /translation="MELNKDIRDRILAAADALYDQAGRASFPTVDSVRKVAKVNMNDA
                     ATTMKEWRRAQTAQAAPVAITVPEAVHQLHSQALAALWQSAQNTANESLRAAQAGWEA
                     ERAEAETINKQLGDAYDAQAVELDAANRQIDELAAKYQAEQQRTTELTQKIEETRKAT
                     LVAENRAAIAEQRALEIERRATDLRAELDRAHQDAVATRTELVDVRQAQQDQRKTAAQ
                     EALRAAERLTATQAERDEARKETAKAREETAHWRGQVEALKEQQRGLLAAIKTGKKPA
                     GAGE"
     gene            1595..1939
                     /locus_tag="PK063_18820"
     CDS             1595..1939
                     /locus_tag="PK063_18820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraO"
                     /protein_id="HMZ99156.1"
                     /translation="MKQRLLVMNGQKIVQHEQEGRWLNDKVEKAGLVKPGIYNLYLAS
                     QADKTNTHDGVILHVDIDNVFQQVGKNVVKHDRVDFVKAPVIGGQSSITYDQGKAIGS
                     VLSHALSRGVSR"
BASE COUNT          646 a          894 c          826 g          460 t
ORIGIN      
        1 ccttcaactc cggccgctgc cgtgacgtga cggtgatcaa cgagctcgtc accgctcaca
       61 agaaagcgcg caacgaggtc ggcctctggt tggccgacga tacccaggaa atcacgcgcg
      121 gatcggtcaa gctgctgcgc gagtacctcg acgacaagcg ccaacacgag cacgacgaag
      181 gcaattccga cacggtcgaa agtaccgcaa gcgcgcgcac agtggcaggg gagggcgagg
      241 aagccaccca ctccaggaga gaatcaaagg cagtcgaccc ggacaggctg agaagggcga
      301 tcgttcacgt gcagcatgac ggccgtcctg cccgcctgat cctcaatcgc cgcccaccgc
      361 tcgaaggcca tgcctggttg aagtacgacg atgacggcca cgagctcgct gccgacctcg
      421 ctcaggtcca gctcgtagcc cttctggaag gctgaccggc cagtctcgcg agcgtcaccc
      481 caggaacccg ccttgtgcgg gtgttcttct tggcgccggc aggtagcggt cacgccgaga
      541 taacgattga tgcatgttaa cgttattatt cttcttcttt ccattatttg acgtgggagc
      601 cgcgaacatg gaactcaaca aggatattcg cgaccgcatt ctcgccgcag ccgatgcgct
      661 ctatgatcag gccggccggg cctcgtttcc gacggtagac tctgttcgca aggtcgccaa
      721 agtcaacatg aacgacgccg ccaccaccat gaaggaatgg cgacgtgcgc agaccgccca
      781 ggcggcgccg gtagccatca ccgtcccgga agctgtccat caactgcata gccaggcctt
      841 ggccgccttg tggcagtccg cccagaacac cgccaatgag tcactgcggg ccgcacaagc
      901 gggctgggaa gccgaacgtg ccgaagccga aaccatcaac aagcaactgg gcgacgccta
      961 cgacgctcag gcggtcgaac tggatgccgc caatcgccaa atcgatgagc tggccgcgaa
     1021 gtatcaggcc gagcagcagc gaaccactga actcacgcaa aagatcgagg aaacgcggaa
     1081 agccacgctg gtcgccgaga accgggccgc tattgccgag cagcgtgccc tggagatcga
     1141 acgtcgcgca accgacttgc gggccgaact tgatcgagcc caccaggatg ccgtcgcgac
     1201 ccgcacggaa ctggttgacg tccgtcaggc tcagcaggac caacgcaaga ccgccgccca
     1261 ggaggctctc cgcgccgccg aacgcctcac cgccacccag gccgagcgcg acgaggctcg
     1321 caaggaaact gccaaagccc gcgaggaaac cgcccactgg cgtggtcaag tcgaggcgtt
     1381 gaaggagcaa cagcgcggct tgctggctgc gatcaaaacc ggcaagaagc cggccggggc
     1441 aggggagtga cgtccgaaaa gactgatcaa acaaaaagcc ttgcgataaa cttcgctgcc
     1501 tttctactcc atgcgacaag gcaatggaca tcactgaata cgctgctgtg atattggaac
     1561 cggatatgac cgtgcgctcg gacaggagca aggcatgaaa caacgcctcc ttgtgatgaa
     1621 cggccagaag atcgttcaac acgagcagga aggccgctgg ctgaacgaca aggtggagaa
     1681 agccggactc gtgaagcccg gcatctacaa cctctatcta gccagtcagg ccgacaagac
     1741 caacacccat gatggcgtga tcctccacgt tgacatagac aacgtttttc agcaggtcgg
     1801 caagaacgtc gtcaagcacg accgggtgga tttcgttaaa gctccagtaa tcggaggcca
     1861 gtccagcatc acttatgacc agggaaaagc cataggttcg gttctctcgc acgcgttgag
     1921 ccgtggcgtg tcgcggtgat ccgactttag ccgctaaacg ccggacgcca cgctctgagc
     1981 catcctctat gtccgttttt gccactcagg cccgcgcgtg gcctggagag accaaccgga
     2041 cgaacagctg ttcgagccga gcgcgaacgg gccagatcag attgacagca gtcgttcagg
     2101 ttcctcgggc tactggcggc cagcgaccca tacctgcctg atgacaaaca agagtcctct
     2161 ggaagcccac caagcagaaa gatgccggtt aggagctgca actgggtgcc tccgggtcgc
     2221 gaactacggt cgctggccgc ggctgctcaa gcagcgccag atgattaaca acagccggcc
     2281 gtgattacat caacccctat tgagacccat cgactcgtgc ggtccgtttt ttggcgaatg
     2341 cctatcaatt acgattccct cctgtatgct caatctctac ggaggccatg gaggtctcgc
     2401 gcccgcgacc gcatgaaggg cacacaaagc ccattgtgtc atcttccagc ttgtagggca
     2461 cggcgaggac atccgctcca aggaagcgat ccagccagcc cactgccgag tcgttcgccg
     2521 cccaagagct cattgcaggc atcaaggtgg gaatccactt cttgcagctc gggcacgcct
     2581 cggtccccca cctggtggag caatcggggc acacacagga aaaccgatgc ccccggccgc
     2641 ccgtgaagtc ccgcctcggg tcggcgatgg ttccgcaagt tgggcaagag agcagcgatt
     2701 tcacgagtcc gatggcgccg tccaacgctt tcgagaattc ggccagggaa tcgatctgcg
     2761 atcgaaggcc agtgatcgag gcgttcaacg ccttcttgcg agcgttcagc ggcccgctcg
     2821 caccgc
//
LOCUS       DAOQPD010000171         2606 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_31990_length_2606_cov_25.524108, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000171 DAOQPD010000000
VERSION     DAOQPD010000171.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 2606)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2606)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2606
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_31990_length_2606_cov_25.524108"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..815)
                     /gene="kdsA"
                     /locus_tag="PK063_18825"
     CDS             complement(<1..815)
                     /gene="kdsA"
                     /locus_tag="PK063_18825"
                     /EC_number="2.5.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008676 - 3-deoxy-8-phosphooctulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-8-phosphooctulonate synthase"
                     /protein_id="HMZ99157.1"
                     /translation="MAYEVDLGQFKIGVGSRPFLIAGPCVIESEQLVMDTAGRIAEIT
                     KSLGMPYVFKSSFDKANRTSISSFRGPGLEKGLAVLAKVKQQIGVPILTDVHSEEQAT
                     EAGHVVDMLQIPAFLCRQTDLLIAAAKTGKVVNIKKGQFLSPPEMGNAVKKVEDAGNR
                     RIVLTERGSSFGYNNLVVDMRSFPIMRRFGYPVVFDATHSVQLPGGGGTKSSGQREFV
                     EPLACAAAGAGCDGFFMEVHPDPDSALSDGPNMVPLHALHSLLERVLRICDAAA"
     gene            complement(959..2560)
                     /locus_tag="PK063_18830"
     CDS             complement(959..2560)
                     /locus_tag="PK063_18830"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HMZ99158.1"
                     /translation="MSKLIFVTGGVVSSLGKGLASASIGNLLESRGLKITFLKLDPYI
                     NVDPGTMNPYQHGEVYVTEDGAETDLDLGHYERYTSLTLTRENNYTTGRIYHSVITKE
                     RRGDYLGGTVQVVPHVTDEIKQCIMRTSQGMDVTIVEIGGTVGDIESLPFLEAIRQLP
                     YDVGRDNVLYVHLTLVPYIGAAGELKTKPTQHSVNKLREIGIQPNILLCRTDRYLPPE
                     LKAKIAMFCNVEKDAVITAKDVETIYEVPIVFRKEGLDELIVRQLKLETGPPNLREWD
                     AMVQKIKHPKHEVSIALVGKYAGLKECYKSLAEALVHGGIDHETRVNVTWIESEDVER
                     QGTERILREADGILIPGGFGSRGIEGKIVTIQYAREHQIPFLGLCLGMQCATIEFARN
                     VAGLTGANSAEFDAQSPHPVIHLMSDQQSVNDKGGTMRLGAYACTLGEGTLAQKMYGV
                     SEVRERHRHRYEFNNAYREQLTAKGLILSGLSPDGRLVEIVELQNHPWFLATQFHPEY
                     KSRPHHPHPLFSGFVGAALRRKCGH"
BASE COUNT          518 a          744 c          760 g          584 t
ORIGIN      
        1 gcggctgcgt cgcatatacg taatacccgt tcaaggagtg aatgaagcgc atgaagcgga
       61 accatgttcg gtccatcgga tagagcggaa tcgggatccg ggtgcacctc catgaagaac
      121 ccgtcgcagc cggctcctgc cgcggcgcag gccaagggtt caacgaattc acgctggccg
      181 ctggatttgg tgccgccccc gccaggcagc tgtacactat gagtggcatc aaagaccacc
      241 ggatagccaa agcggcgcat gatgggaaat gagcgcatgt cgacgaccag attgttgtac
      301 ccgaacgagg agccccgctc cgtcaggacg atacggcggt tgccggcgtc ttcgaccttc
      361 ttgacggcgt tgcccatttc cggcggcgac aggaactgcc ccttcttgat gttcacgacc
      421 ttgccggtct tcgcggcggc aatcaacagg tcggtctggc ggcagagaaa agcgggaatc
      481 tgcagcatgt ctacgacatg gccggcctct gtcgcctgct cttccgaatg gacgtcggta
      541 agaatcggca cgccgatctg ctgcttgacc ttggccagaa cggcaagacc cttttctaag
      601 ccgggtcccc gaaaggagga gatggaggtg cgattcgcct tatcaaagga ggatttgaac
      661 acgtagggca tgccgagtga tttggtgatt tcggcgatac gtcccgccgt atccatgacg
      721 agttgctcgc tttcaatcac gcaaggcccc gcgatcaaaa acggccgact ccccactccg
      781 atcttaaatt gtccgagatc aacttcgtac gccatagtct tctcttctga attcgcggga
      841 tgctcaaact gatctttcag caaggccgca gacgaggcag agccggaggc gtagcggagc
      901 tacgtcgagg actgtgccga gtcgagaacg ccgcagaaag gcagtttcag catcccattt
      961 agtggccgca tttgcggcgt agtgccgccc ccacaaatcc gctaaacaaa ggatgcggat
     1021 gatgcggccg tgacttgtat tccggatgga actgcgtggc caggaaccag ggatgatttt
     1081 gcagttcgac aatttcgacc aggcggccat ccggtgacag gccgctgaga atcagtccct
     1141 tcgccgtcaa ttgttcgcga taggcattgt tgaattcata ccggtggcga tgccgttcgc
     1201 gcacttcgct gacgccgtac attttttgcg ccagggtgcc ttctcccaat gtgcaggcgt
     1261 aggcgccgag gcgcatcgtg ccacccttgt cattgacgga ttgctggtca gacatgagat
     1321 ggatgaccgg atgcggcgac tgcgcatcaa actccgcgct gttcgcgccg gtcaatccag
     1381 cgacgttgcg cgcaaactcg atcgtggcgc attgcatccc cagacagagg ccgaggaagg
     1441 gaatctggtg ttcccgcgca tactgaatgg tgacaatctt gccttcgatt ccccgtgagc
     1501 cgaaaccgcc gggaatgaga atgccatcgg cctcgcgcaa gattcgttct gtcccctggc
     1561 gttccacgtc ttcggattcg atccacgtga cgttcacgcg ggtttcgtgg tcgatcccgc
     1621 cgtgcaccag ggcctcagcc aggctcttgt aacattcctt cagtccggca tattttccga
     1681 cgagcgcgat cgacacttcg tgtttgggat gcttgatctt ctgcaccatc gcgtcccatt
     1741 cgcgcagatt gggcgggccg gtttcgagct tcagctgccg gacgatcagc tcatccagcc
     1801 cttccttgcg gaacacgatc ggcacttcgt agatggtttc cacatccttg gccgtaatga
     1861 ccgcgtcctt ttccacgttg cagaacatgg cgatcttggc tttgagctcg ggtggaaggt
     1921 agcgatccgt gcggcataac aggatgttcg gttgaatacc gatttcgcgc agcttgttga
     1981 cggaatgctg ggtcggtttg gttttcaact cacctgcggc gccgatgtac ggaaccaggg
     2041 tcaggtgcac atagagcacg ttgtcgcgtc ccacgtcata gggaagttgc cgaatggctt
     2101 ccagaaacgg caggctttcg atatcgccga ccgtgccgcc gatttccacg atcgtgacgt
     2161 ccataccttg cgacgtccgc atgatgcatt gcttgatctc atcggtcaca tggggaacca
     2221 cctggaccgt tccgcccaaa tagtcaccgc gccgctcttt tgtgatgact gagtgataaa
     2281 tacggccggt ggtgtagttg ttttcgcgcg tcagcgtgag cgaggtgtat cgttcgtaat
     2341 gccccaggtc gagatcggtc tcggccccgt cttccgtcac gtaaacctcg ccgtgctggt
     2401 agggattcat ggtgcccggg tcgacgttga tgtaggggtc gagtttcaaa aaggtgattt
     2461 tcaacccgcg gctttccagg agattgccga tggacgcgga agccagtccc tttccgagcg
     2521 acgatacgac acccccggtc acaaagatca gcttgctcat cgtggcacct tcttgtgaat
     2581 gcggccaata gtcatggttg agtgct
//
LOCUS       DAOQPD010000172         2524 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_33905_length_2524_cov_18.302552, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000172 DAOQPD010000000
VERSION     DAOQPD010000172.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 2524)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2524)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2524
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_33905_length_2524_cov_18.302552"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..511
                     /locus_tag="PK063_18835"
     CDS             <1..511
                     /locus_tag="PK063_18835"
                     /inference="COORDINATES: protein motif:HMM:NF021021.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="M64 family metallopeptidase"
                     /protein_id="HMZ99159.1"
                     /translation="DNPLGAAIMVSPKSGHSFTAADAARFGAGCVLYLPVEASESARS
                     EDYPFAELIALNVKDHITDRGCALNQDPDSDEICVPDKNDIQKPKKLDIDFPRCFKHK
                     NRIVGLFTGGKTFHCGIYHPTGNCIMRNSDSDGKEFCPVCRYLLVDIIDPHQHFSIDL
                     DYGEIYPQK"
     gene            508..>2524
                     /locus_tag="PK063_18840"
     CDS             508..>2524
                     /locus_tag="PK063_18840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99160.1"
                     /translation="MSGTAGTFEQIARGMIDAMAPLRHALSSPDAFRSFMLRLGWETI
                     SVPPAYTALSTTIADAMQAVESLKDDPTAEEVLALLRKAQATYVAIQGIDQAPAGVDA
                     STFLSEMGERLFELLLTDYLAAHQPALFNLLSILNVIETEQIAATANQRAHVRTHFHW
                     ANIPEIIRDPASLPQRVYGWGTQELKFQLILQHFSELLFAFGFPVFIGKAEELLANGY
                     AGEDIDLDEETRWLKVPFYYITIADRDLEAAISVVELKGNGTTLPGLAIQPHIPSEFP
                     LTLHLAPTIDFRLRAGTNAATQVGIVLRPGDASIKYPFEPGTTPPSAGIGLGFDFKPS
                     SPTLLFGSPNATRLELQGASVDLGASFVQNELDVQVAAQLKGLTLVLQPGEADSFLRN
                     LFGDSERRLTIPLGFEWSRRNGVHFAGSDAFETSLPANLSLGPVTVQGLTVQLFAPTD
                     HSADLTLGVGAQISGTLGPVSFAVEGMGFRLQTTFAPGNAGPFDLSLGFKPPTGLGLA
                     ISTPGVTGGGFLGFDPQRAEYSGMLQLELAETLALKALGLLTTRLPDGSRGYSLIVIL
                     TAEGFAPIPVGLGFTLTGIGGLVALHRTVRTDVLREGLKTGTLNAILFPRDPLRNAPQ
                     IFSDLRRVFPPTAGRHVVGPMVQLRWGTPTLLTLDLALLVELPAPIRV"
BASE COUNT          470 a          857 c          705 g          492 t
ORIGIN      
        1 ggacaatccc ttgggcgcgg ccatcatggt ctctcccaaa tccggccact catttaccgc
       61 cgccgatgcg gcccggttcg gggccggttg cgtcctctac ctgccggtgg aggccagtga
      121 atcggcccga tcggaagact acccttttgc cgagttgatc gccctgaacg tcaaggatca
      181 catcacggac cgcggctgcg cgctcaacca ggatcctgac agtgatgaga tctgcgtgcc
      241 ggacaagaac gacattcaga agccgaaaaa gctcgatatc gattttcccc gctgcttcaa
      301 acacaaaaac cggatcgtcg gcttgttcac gggaggaaag acgttccatt gcgggattta
      361 tcatcccact ggcaactgca tcatgcgtaa ctcggacagc gacggaaaag agttctgccc
      421 cgtgtgccgt tacctgctgg tggatatcat cgatccccac cagcattttt ccatcgacct
      481 ggactacgga gagatttacc cgcagaaatg agcggcacgg ccggcacatt cgaacagatt
      541 gcacgcggca tgatcgacgc gatggcgccg ttgcggcatg ccctgagcag tcccgatgcc
      601 ttccggtcct tcatgctccg cctcggctgg gaaaccatct ccgttccccc ggcctatacc
      661 gcgctcagta cgacgatcgc cgacgccatg caggcagtgg aatccctcaa agatgatccg
      721 acagcggagg aggtgctggc cctgctcaga aaagcccaag cgacctacgt cgccatccag
      781 ggtatcgatc aggctccggc cggcgtggac gcgagcacct ttctgagcga gatgggcgaa
      841 cgactgttcg aactcctcct gacggactat ctcgccgcgc atcaaccggc gctgttcaat
      901 ctgctctcta tcctcaatgt gatcgagacg gagcagatcg cggccacggc caatcagcgc
      961 gcgcacgtgc gcacacactt ccattgggcc aatatcccgg agatcattcg cgatcccgca
     1021 tcccttccgc aacgggtgta cggatggggc acgcaggagc tcaagttcca gctcattctc
     1081 cagcacttca gcgaactgtt gttcgcattc ggtttccccg tcttcatcgg caaggcggag
     1141 gagttgctgg ccaacggata tgcaggtgag gacatcgacc tggatgaaga gacgcgatgg
     1201 ctcaaggttc ccttctatta cattacgatc gccgaccggg acctcgaagc tgccatcagt
     1261 gtggtagaac tgaaaggcaa cggcaccacc ctgcccggcc tggccatcca accccacatt
     1321 ccgagcgaat tcccgctgac cttgcacctg gcgccgacca tcgatttccg cctgcgtgcc
     1381 ggcaccaacg ccgcaactca agttggcatc gtgctccgcc ccggcgacgc gtcaatcaag
     1441 tatccatttg aaccgggtac cacaccgcct tcggccggca tcgggctcgg gttcgatttc
     1501 aaaccatcgt ccccgaccct gctgttcggt tcaccgaacg ccacccgtct tgaactccaa
     1561 ggagcatcgg tcgatctggg agcctccttc gtccagaatg aattggacgt ccaggtagcc
     1621 gcgcaactca aaggcctgac gcttgtcttg caaccgggtg aggccgattc cttcctgcgc
     1681 aacctgttcg gcgatagcga acgccggctc acgattccgc tcggtttcga atggtctcga
     1741 cgcaacggcg tgcacttcgc aggaagcgac gccttcgaga catccttgcc cgcgaatctt
     1801 tcgcttggac ccgtcacggt ccaagggctg acggtccaac tctttgcgcc gaccgaccat
     1861 tccgcggacc tgacccttgg agtgggggcg cagatctcgg gcacactcgg ccccgtctcg
     1921 tttgcggtag aaggcatggg gttccgtctt caaacgacct ttgctccggg caacgctggt
     1981 ccgttcgacc tctccctcgg cttcaaaccg ccgacgggcc tcggcctggc gatcagtacg
     2041 ccgggggtaa ccggcggcgg gttcctgggc ttcgatcccc agcgggccga atacagcggc
     2101 atgctgcagc tggagctggc cgagaccctc gcgctcaaag ccctgggcct gctcaccacc
     2161 agactgcccg atggcagtcg cggctactca ctcatcgtga tcctgacggc cgaaggcttc
     2221 gcgcccattc ctgtcggctt gggcttcacc ctcaccggca tcggcggctt ggtcgcgctg
     2281 caccgcaccg ttcgcaccga cgtgctgcgc gagggcctca agaccgggac gttgaatgcc
     2341 atcctgttcc cccgcgatcc cctgcggaat gcgccccaga tcttcagtga cctgcgccgc
     2401 gtgtttcccc ccaccgccgg ccgccatgtg gtcggcccga tggtgcaatt acgctggggc
     2461 accccgacgt tgctcacgct cgacctggcc ctgctcgtcg aactgcccgc gccgattcgc
     2521 gtgg
//
LOCUS       DAOQPD010000173         2508 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_34315_length_2508_cov_27.869547, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000173 DAOQPD010000000
VERSION     DAOQPD010000173.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 2508)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2508)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2508
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_34315_length_2508_cov_27.869547"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..857
                     /locus_tag="PK063_18845"
     CDS             <1..857
                     /locus_tag="PK063_18845"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99161.1"
                     /translation="WEDMAELDYTVPAPRGTRAAQATDATVDTPLCPDCGSSSVVVSM
                     MTVGVHQLDLKEAHCLICAWRVELGRKPSATVDVESDLELEDHGDGTLVGPIDESEES
                     ADDGEQDIVPSSMTGEEETQRSVVEDFETQDMESAEDPVDQLMTLQNRFWQDWTVKPL
                     RCALLEGTMRERLSGERLDMIWAVASTLMESCRGLGRAEQQEIARWLMRTSTEELRAF
                     LPESELPAELAQPERMLVVPSVSTKIQKWQLACRLALRRFRVASAGVRILAPSFGVSP
                     DVFRAASA"
     gene            953..1207
                     /locus_tag="PK063_18850"
     CDS             953..1207
                     /locus_tag="PK063_18850"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99162.1"
                     /translation="MNAIDTIINEIVQHIHGSSCIPETYEAAFVTAVWERAQALEAPL
                     RDELLCRTGVTQDSLKQVREEAADALYEAHRALYGTAWEW"
     gene            complement(1362..1694)
                     /locus_tag="PK063_18855"
     CDS             complement(1362..1694)
                     /locus_tag="PK063_18855"
                     /inference="COORDINATES: protein motif:HMM:NF012651.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HMZ99163.1"
                     /translation="MTYAHVELVGRVATTPVRATVGARRVTNLRVAIDRPIQTTRPGH
                     TPPLFLSVCIWDHTLDHQLPSLTKGQTVKVTGRLDTRTSSHTGLTYTHVVTDHIELMP
                     PEIHRQAA"
     gene            complement(1757..>2508)
                     /locus_tag="PK063_18860"
     CDS             complement(1757..>2508)
                     /locus_tag="PK063_18860"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99164.1"
                     /translation="APELPGLDAEDIAQNEERVARAWYVDHGQQAEAGDDDALDLDSG
                     QDSEDLFDDTTQIDTFEYLDYESSHEIAQDDIPNDESDVDLPDLQDKLHAPAYALFCQ
                     GRHPLRQALLNQAILELDAHDNRMPVWVAAGRILTSTPHHLSPTDAQAITSWLHGLPQ
                     EDLAILAGDPNASNERLAHPEPGLFFPTDQLLLPLIRFFGHSLKRFRNKEAGCRILAA
                     DYGLTESALKHIAMAYGQLPANREASHMPAA"
BASE COUNT          492 a          617 c          857 g          542 t
ORIGIN      
        1 cgtgggaaga catggccgaa ctggattaca cggtgcctgc tcctcgtggg acacgtgctg
       61 ctcaagcgac cgatgcgaca gtcgatacac cgctgtgtcc cgactgtggc tcgtcgtctg
      121 tggtggtgtc catgatgacg gtcggtgtcc atcagttaga tctgaaagag gcgcattgtc
      181 tgatttgcgc gtggcgtgtc gaactcggac gcaaaccgag tgcgacggtc gatgtggaat
      241 cggatcttga gctggaggat cacggagacg gaacgcttgt ggggccgata gacgaatctg
      301 aagaatcagc agacgatggc gaacaggaca tagtgccgag cagcatgacc ggcgaggagg
      361 agactcaacg cagtgtggtt gaggactttg agacgcagga tatggagagc gcggaagatc
      421 ctgtagatca gctgatgacc ttgcagaatc gcttttggca agactggacg gtcaagcccc
      481 ttcgttgcgc actattagag ggcacgatgc gggaacgact gagtggggag cggcttgata
      541 tgatttgggc cgtagcgtcc acactcatgg aatcgtgccg tgggctgggt cgcgcggagc
      601 aacaggaaat cgcacgttgg ctgatgcgaa cgtcgaccga ggagttgcgc gcgtttctcc
      661 cagagtcgga attgccggca gaattggctc agccggaacg tatgttggtc gtgccgtccg
      721 tatcgacgaa gatacagaag tggcagctag catgtcggct ggcattgaga cgattccgag
      781 ttgccagcgc gggtgtcaga attttggccc cgtcgtttgg tgtctcaccg gacgtatttc
      841 gagccgcgag tgcctagtgc ccgtgtcgat aggggagcag cagagggagc gcgtggtttc
      901 ttggagagca cgcctctctc tgtgcccttg tcaactatgc ctggaggctt tcatgaatgc
      961 gatcgacacc atcatcaacg agattgtcca acacatacac ggatcgagct gcatccctga
     1021 gacgtatgaa gccgccttcg tgacagccgt ctgggagaga gcgcaagccc ttgaagcccc
     1081 gcttcgagat gagctgcttt gtcggacggg cgtcactcag gactcgctga agcaggttcg
     1141 tgaagaagct gccgatgcgc tctatgaggc tcatcgcgca ttgtatggga cagcgtggga
     1201 atggtagttt tggactagaa ctccttacgc atggccccat gtaaggaccg acaccagtac
     1261 atgaggggag acacttcgtt gtggaagacg cgagttcctt ggaactcagt gcgtcttccc
     1321 ggaagtgctc cccttttttt tgccttgccg ccggccgggg cttaggcagc ctgtcggtgt
     1381 atctccggtg gcatcagttc gatgtggtcg gtgacaacat gagtatacgt cagtccggtg
     1441 tgcgaggagg tgcgggtatc caagcgccct gtaaccttga ctgtttggcc cttcgtcagg
     1501 gaggggagct ggtggtcgag ggtgtggtcc cagatgcaaa cggagagaaa cagtggtgga
     1561 gtgtgtccag gacgagtggt ctgaataggc cggtcgatcg cgacgcggag attggttacc
     1621 ctgcgtgcgc cgactgtggc gcgcacggga gtggtcgcga cacggccaac gagttcgacg
     1681 tgagcatagg tcatgaaaag actccttcac atggttgagc ggagggatgt gcactgccgt
     1741 atcactaagg gcgagactag gctgcaggca tgtgggaggc ctcgcggttg gctgggagtt
     1801 gcccgtaggc catggcgatg tgtttgagcg cggattctgt cagcccatag tccgcggcga
     1861 ggatgcgaca gccagcctcc ttgttgcgaa agcgtttcag actgtgtccg aagaagcgaa
     1921 tcaatggtag caggagttga tcggttggga agaacaaccc gggttccgga tgcgctaagc
     1981 gttcgttgct ggcgttggga tcgccagcca ggatggcgag gtcctcttgt ggaagcccat
     2041 ggagccagct tgtgatggcc tgcgcgtcgg tcggagagag gtggtgtggg gtggacgtga
     2101 ggatacgccc ggccgcaacc cagaccggca tgcgattgtc gtgggcgtcg agctcgagga
     2161 tggcttggtt gaggagggcc tgtcgaagtg ggtgacggcc ctgacagaac agggcataag
     2221 ccggtgcgtg gagcttgtct tgcagatcag gcaagtccac gtcgctctcg tcgttcggga
     2281 tgtcgtcttg ggcaatttca tgggaagact cataatctag atactcaaac gtgtcgatct
     2341 gcgtggtgtc gtcgaacaga tcctcgctgt cctggccgct gtcgagatcg agggcgtcgt
     2401 cgtcgccagc ttcggcctgc tggccgtggt ctacatacca ggctcgcgca actcgttctt
     2461 cgttctgcgc gatatcctcg gcatcgagac cgggcagctc gggggcat
//
LOCUS       DAOQPD010000174         2438 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_36119_length_2438_cov_19.206462, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000174 DAOQPD010000000
VERSION     DAOQPD010000174.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 2438)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2438)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2438
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_36119_length_2438_cov_19.206462"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..2118)
                     /locus_tag="PK063_18865"
     CDS             complement(<1..2118)
                     /locus_tag="PK063_18865"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99165.1"
                     /translation="MPITGIQWKSNREYDIHLLRGRTLSPLLAQVNVELPDGNTQDAA
                     TYLAANADVTIDFQPSFRNVLDVTATPPTCTGFGITINNTNGEVRVPSPPTPAPVIHN
                     FLLHATAQDSSDGKEYRISVRIHLHNRVTSAWLTPPILTLRPDGPTLPQTTFRRFTVR
                     AQFDDNTVGDLTNQQGLTWGPLGNVEPSGRLVISVGNSPSDPAVEITATLPADLRDPG
                     NPTPPDIVARGHIRFAADWASESTIKTETVQVQDTWPGTINPELVPNFLFLSDGYLAE
                     DKPQFESQIRSLLGLMKKSRLTRPFDLLSTSMNYFQAFVPSSHHGISVLCEVYPAQKK
                     SGEVQTNSDDTVNLYCIPDPSDPAAGARWDLSNLLFRLGLPVPGQGLDRPVKEIRDYW
                     DSILDAVPHDRISNETVRRWQKLARRTFLEETDSTFGLAYGDYPNVTNESDSREVGFH
                     PRRMSRERLDTILNRLHDSHGNPMGQLWAARADGTRPNSYPLIFLFSSLKWDRGVNYG
                     RSYIAMNVEERYEIPARPVSGKPTYGIDLTGRITKNISHGRLIRGCHEVAHSFGLGDE
                     YSEKGTLPQSREIDRFYGNLQKHNDLLDSFKDIDGDLIKWRWHRIRKATVLMGAISEG
                     PSGVFRIPIPLGQSRQFKQGNTVLLRARRYPIPLPRNPDTSEHLQIVGLADPGGVADL
                     SKPEGPDNPLGAAIMVSPKSGHSF"
BASE COUNT          458 a          650 c          796 g          534 t
ORIGIN      
        1 aaatgagtgg ccggatttgg gagagaccat gatggccgcg cccaagggat tgtccggacc
       61 ttccggtttt gagagatcag ccactccgcc cgggtccgct agtccgacga tctgcaggtg
      121 ttcgctggtg tccggattgc gcgggagggg aatgggatat cgtcgagcac gcaggagtac
      181 tgtgttgccc tgtttgaact ggcggctttg gcctaatggg atcggaatac ggaagacgcc
      241 ggagggtcct tcgctgatgg cccccatgag cacggtggct ttgcggatgc gatgccagcg
      301 ccatttgatg agatcgccgt cgatgtcttt gaaagaatcg agcaggtcgt tgtgtttctg
      361 gaggttgccg tagaaccggt cgatttcacg gctttggggc aacgtgccct tttcgctgta
      421 ttcgtcgccc aggccgaagg aatgcgccac ctcgtggcaa ccgcggatga ggcggccatg
      481 cgagatgttc ttggtgatgc ggcccgtgag atcgatgcca tacgtcggtt tcccggagac
      541 gggcctcgca gggatttcgt agcgctcttc gacattcatg gcgatatagg agcgcccgta
      601 atttacgccg cgatcccatt tgagagagga gaagaggaag atcagcgggt agctgttggg
      661 acgcgtgcca tccgctcgtg cggcccagag ttggcccatg ggattgccat ggctgtcgtg
      721 caggcggttc aagatcgtat ccagccgctc ccgagacatt cgtcgcggat gaaagccgac
      781 ttcgcgactg tcgctttcat tggtgacgtt ggggtaatcg ccgtaggcca atccgaacgt
      841 tgaatcagtc tcttcgagga acgtccgtcg tgccaatttt tgccagcgtc ggacggtctc
      901 attggaaatc ctgtcatggg gcacagcgtc gaggatgcta tcccagtagt cgcggatctc
      961 tttcacgggg cgatcgagcc cctgcccggg aacggggagg ccgagcctga acagcaggtt
     1021 gctgagatcc cagcgtgccc ctgcggcggg gtctgaggga tcagggatgc aatagagatt
     1081 cacggtgtcg tcgctattgg tttgcacctc cccgcttttc ttctgcgccg ggtacacctc
     1141 acaaagcacc gaaatcccat ggtggctgga cggcacgaag gcctgaaaat aattcatcga
     1201 cgtggagagc aagtcgaacg ggcgcgtcag cctgctcttt ttcatcaacc cgagcaggct
     1261 acggatttgg gattcgaact gtggtttgtc ctcggcgaga tagccatcgg acaagaacag
     1321 aaagttcggg acgagttcgg ggttgatcgt gccaggccag gtgtcctgca cctggacggt
     1381 ctccgttttg attgtgcttt ccgacgccca atcggctgcg aaccggatat ggccgcgcgc
     1441 tacgatgtcc ggtggtgtgg gattgccggg atcccgtaga tcggctggaa gcgtggcggt
     1501 gatttcgacg gcggggtcgc tggggctgtt tccgaccgaa atgaccaatc ggccggatgg
     1561 ctccacgttg cccaatgggc cccatgtcag tccctgctga ttggtcaggt cgccgacggt
     1621 gttgtcatcg aactgtgcgc gcaccgtgaa tcgtctgaac gtggtttgcg gcaaggtcgg
     1681 accgtccggc cgcaacgtca ggatcggcgg cgtcagccag gcggaagtca cacggttatg
     1741 aaggtgaatc cggacgctga tgcggtattc cttcccgtcg ctcgaatcct gcgccgtggc
     1801 gtgcagcaga aaattatgaa tgaccggcgc tggagtagga ggcgacggga cacggacttc
     1861 accgttggta ttgttgatgg tgatgccgaa gccggtgcag gtcggcggtg tggcggtcac
     1921 atcgaggacg ttgcgaaacg aaggctggaa atcgatggtg acatcggcat tggccgctaa
     1981 ataggttgct gcatcttgcg tgtttccatc cgggagttcg acattcactt gagccagaag
     2041 gggagagagg gtcctgccgc gcagcaggtg gatgtcgtac tctcgattgc ttttccattg
     2101 gattccggta atcggcatgg tgactagtgc tgtctggtga tctctgaacg gtgacggaat
     2161 aagaaaatac gttgcctcgc acgacgtcgt cgaacaggat cagacacgat catgaaggga
     2221 tgagccgaaa ggtactccgc tcgtgatggc ctgtcaaact cgtctctgcg caaatacctg
     2281 cattgtgatg acgcagtctg cgacacacca tgtctatgcg actaccgctg tcgtccctcg
     2341 ccgtttgcgc gccggggcct gccctgcggc gccgaagcgg gccacccgct ccaacaccgc
     2401 cgccgagagc acatagcccg gtttcggccg ctccggcg
//
LOCUS       DAOQPD010000175         2404 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_37070_length_2404_cov_29.238825, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000175 DAOQPD010000000
VERSION     DAOQPD010000175.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 2404)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2404)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2404
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_37070_length_2404_cov_29.238825"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..789
                     /locus_tag="PK063_18870"
     CDS             <1..789
                     /locus_tag="PK063_18870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012607313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - transposition, DNA-mediated
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HMZ99166.1"
                     /translation="QPYLFKLKLSKNVKRHISHLCDGTDWTDAGQGWEGKDGQLALQG
                     WDHKRRVVVLRRPLTREKVAQEENGQLMLSFIEANRKRGKEITGYEYAVLVTNTSYEI
                     LSLGQLYRDRADAENAFDELKNQWGWGGYTTHDLHRCQLAARAVALIYNWWSLFVRLA
                     NPESRREAITSRPWLMTSVGRKTEHAGQTTVTLTGLHAHFAQARAALTRVSALLQGWV
                     AETAEQLAHPSVWHRVCDHLKQILAGIEGPPRHQLLGNYAKGVS"
     gene            834..1160
                     /gene="kleE"
                     /locus_tag="PK063_18875"
     CDS             834..1160
                     /gene="kleE"
                     /locus_tag="PK063_18875"
                     /inference="COORDINATES: protein motif:HMM:NF036636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KleE stable inheritance protein"
                     /protein_id="HMZ99167.1"
                     /translation="MTNIIQFPKRDSPAPTRDLAPPVVQPKPLDGAAGGRVLSNLIKV
                     VWVVTVLLWPLMKWILSLDVLFQAARMIYHWNTPDVYATWTFLLHVAVLVVPTYFVSL
                     YKPKGI"
     gene            1374..1679
                     /locus_tag="PK063_18880"
     CDS             1374..1679
                     /locus_tag="PK063_18880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator KorA"
                     /protein_id="HMZ99168.1"
                     /translation="MKKRLTEPEFQKAINGLDVGSQTLEIARGVLIDGKPQKEFAAAL
                     GLSRGAISQAVNRVWAAHGDSNLPEGYVRVSAILPEHRAFIVKKWVEDARKKRQHKK"
     gene            1684..>2404
                     /locus_tag="PK063_18885"
     CDS             1684..>2404
                     /locus_tag="PK063_18885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011114061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HMZ99169.1"
                     /translation="MKTLVVANQKGGVGKTSTLVHLAFDFLEQGLKVVVIDLDTQGNA
                     SYTLQSFRSGLVASELFTDVPTGSWPQTGIDVTAPNSPRMTLIASDVGLANLEKISLA
                     EAGAKFRDAIKALGAQGFDACLIDTAPSLGVGMAAALLAADYVLSPIELEAYSIQGIK
                     QMVTTIAHLRKANPKLKFLGMVPSKVDARNPRHARHLEELERAYPQLMIPTGVGLRSS
                     IADALASRVPVWKIKKTAARKA"
BASE COUNT          498 a          723 c          714 g          469 t
ORIGIN      
        1 cagccctatc tgttcaagct caagctgtcc aagaacgtca agcggcatat cagccacctc
       61 tgtgacggaa ccgactggac ggatgcgggc caaggctggg aggggaagga tggtcaattg
      121 gcgctccagg gctgggacca caagcggcgg gttgtcgtcc ttcgtcgtcc gctcacccgc
      181 gagaaggtgg cacaggaaga gaacggccag ttgatgctgt cgttcatcga ggccaaccga
      241 aaaaggggga aggagatcac cggttacgag tacgccgttc tcgtgaccaa caccagctac
      301 gagattctca gcctcggtca gctctaccgg gatcgggcgg atgccgagaa cgctttcgat
      361 gaactcaaga accagtgggg ttggggcggc tatacgacgc acgacctgca tcgttgtcag
      421 ttggcggctc gtgccgtggc actgatctac aactggtgga gtttgttcgt tcgactggcg
      481 aacccggagt ctcggcgaga ggccatcacc agccgcccct ggctcatgac atccgtcggg
      541 cgaaagaccg agcatgccgg gcagaccacc gtgaccctaa ccggattgca tgctcacttc
      601 gcgcaagcgc gggcggcgct gacgcgagtc tctgccttgc ttcaaggctg ggtggccgaa
      661 actgcggagc agttggccca tccatctgtt tggcatcgtg tctgtgatca cctcaagcaa
      721 attctcgccg gcatcgaggg cccaccaagg catcagttgc tggggaatta tgcgaaggga
      781 gtcagctaac tgcggtttct aggttgaaca tgcttcagcg tggagggcaa gtaatgacga
      841 acatcatcca gtttcccaag cgcgattctc cggctcccac tcgggatcta gctccgccgg
      901 ttgtccaacc caagcccctt gatggcgccg caggagggcg cgttctctcc aacctcatca
      961 aagtcgtctg ggttgttacc gtcctgctgt ggccactgat gaagtggatt ctctctctcg
     1021 acgtgttgtt ccaggctgct cgcatgattt accactggaa cacgccagac gtctacgcca
     1081 cctggacgtt cctccttcac gttgccgtgt tggtcgtacc tacctatttc gtgtcgctat
     1141 acaagcccaa agggatttag ccacgtagtc gtctcgcgtg ccagttagcc cacgactacg
     1201 ctctctcaat cgtccccaac gactgtgctt tgcacaacgc gaccggcaga gagctttagc
     1261 cgctaaagca cttgcttgct catgacgttt agctgaacta ctattgatag gtggcggctg
     1321 tcggcacctc tttgcaacgt gggtgcggac cacgaacagg gtggacacat tccatgaaga
     1381 agcgcctcac cgaacccgaa ttccagaagg ccatcaacgg gctggacgtg ggatcgcaga
     1441 ccttggagat cgcgcgcggc gtgctgatcg atgggaagcc gcaaaaggag tttgccgcgg
     1501 cgctgggctt gtcgaggggt gcgatttcgc aggcagtcaa tcgcgtatgg gcggcgcacg
     1561 gagacagcaa tctaccagag gggtacgtgc gggtctcggc aatcctgccc gaacaccgag
     1621 cattcattgt caagaagtgg gttgaggacg ccaggaagaa gcggcaacac aagaaatgaa
     1681 aaaatgaaga cactggttgt cgcaaaccag aagggcgggg ttggcaagac ttcgactctc
     1741 gttcacctcg cgtttgactt cctggagcaa ggtctaaagg tggtcgtcat cgacctggac
     1801 acccagggca atgcctccta cacgctgcag tccttccgat ccggccttgt cgcaagcgaa
     1861 ctctttaccg acgtaccgac gggctcgtgg ccgcagaccg gaatcgacgt caccgctccc
     1921 aattcgccgc gcatgacgct gatcgcctcc gatgtcggac tggcgaacct ggagaagatc
     1981 tctttggccg aggctggcgc caaattccgg gacgccatca aggctctagg cgcgcagggc
     2041 ttcgacgcct gcctgatcga caccgctccc tcccttggcg ttggtatggc cgccgctctg
     2101 ctggcggccg actacgttct ctcgccgatc gagctagagg cgtacagcat ccagggcatc
     2161 aagcagatgg tcacgaccat tgcccacctt cgcaaggcca accccaagct caaattcctc
     2221 ggcatggtgc ccagcaaggt cgatgctcgc aacccgcggc acgcgcgcca cttggaagag
     2281 ctggaacgtg cctacccaca actgatgatc ccgaccgggg tgggcctgcg cagcagcatt
     2341 gccgacgcgc tggcgtcccg cgtgccggtg tggaagatca agaagaccgc cgcccgcaag
     2401 gcca
//
LOCUS       DAOQPD010000176         2349 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_38699_length_2349_cov_19.343941, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000176 DAOQPD010000000
VERSION     DAOQPD010000176.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 2349)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2349)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2349
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_38699_length_2349_cov_19.343941"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..237)
                     /locus_tag="PK063_18890"
     CDS             complement(<1..237)
                     /locus_tag="PK063_18890"
                     /inference="COORDINATES: protein motif:HMM:NF012314.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HMZ99170.1"
                     /translation="MISEVTDHNFARTVEQAPMPVLVEFWQPGCGHCLALLSQLQLLQ
                     DEVGAAVKIVKMNVQENFQIPAELEISSLPALALF"
     gene            complement(234..905)
                     /locus_tag="PK063_18895"
     CDS             complement(234..905)
                     /locus_tag="PK063_18895"
                     /inference="COORDINATES: protein motif:HMM:NF012863.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDSL-type esterase/lipase family protein"
                     /protein_id="HMZ99171.1"
                     /translation="MTTDNPAPLILCFGDSLTAGYQTPSPAHPSGQDSPYGYVLQEYL
                     GVRGRVEVSGICGETTGEMVLRFRRAVLERHPQMVIILGGTNDLGWNADPAEIMRNLI
                     KMYELARASSIVPVPVTVPSIRVDLGGENPDAAAWLAEHIQRRQRLNALIADYAQRKN
                     LRHVDLFTATAEPESLMLAEPYSNDGLHLTSSGYRVFGRLVYEELFAADPAVSGDASS
                     NLSQP"
     gene            1013..>2349
                     /locus_tag="PK063_18900"
     CDS             1013..>2349
                     /locus_tag="PK063_18900"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99172.1"
                     /translation="MEPTAPVGEGLPLAPFVKPGTDPQVTAIKQLLKLLDKAAKSART
                     YGTKNPVAQRFFQQFYDELTNHLTQHTRLTLLVQRNQLLFQNEVVYEPERDATGDSFA
                     FKMYSDGIRELSFHQGLTHEDLAFFLEALWGMPADEASPADAAADQEEDDDIVTRLWA
                     KNLETITLVTAEELVRASGFGLDELELQTQGYMSLPVGSLRELLDRERAAKASDKEGT
                     GGSAEAAGGNTTGGIANRNRRFQANVVGYDVSDEEHEALTQEIQRETARDATTYILDI
                     LSAVLASEPSPALLTKLFDVWDHVLEALIRAGQWTLLETVLTMLQEAETVRPDLSDGH
                     KQQVAELFGGLGRPERLKAIGVHLNRNPQAKTEGLTTLLLMMKPDAIPGLCSVLATLE
                     TPAHQALVMEALQTLARDHAEPIIRGLTDKRPTFVRNLLTLIYRWNDARFADSV"
BASE COUNT          529 a          714 c          661 g          445 t
ORIGIN      
        1 gaatagggcc agcgcaggca acgaactgat ctcgagttca gcaggaatct gaaagttctc
       61 ctgtacgttc atcttcacga tcttcaccgc ggcaccgact tcatcctgca acagttgtag
      121 ctgcgagagc agtgcgagac agtgcccgca gcccggctgc cagaactcca cgagcaccgg
      181 cataggggcc tgctccaccg tacgcgcgaa gttgtgatcc gtgacctcgg agatcatggt
      241 tgagacaggt tggaagaggc gtcgccggaa acggcaggat cggcggcaaa gagctcctca
      301 tacaccagcc ggccgaacac gcgatagccg ctactcgtca gatgcagccc atcattcgaa
      361 tacggctccg ccagcatcag ggactccggt tcggctgtcg ccgtgaacaa atcaacatgc
      421 cgcagatttt ttctctgcgc atagtccgcg atcagggcat tcaaacgctg acgccgctga
      481 atatgctcag ccagccacgc cgccgcatcg ggattttccc cgcccaggtc gactcgaata
      541 gatgggacgg tgacaggcac gggcacgatc gacgaggccc ttgccaattc atacatcttg
      601 atcagattcc gcatgatctc cgcaggatcg gcattccatc cgagatcatt cgtgcccccc
      661 agaataatca ccatctgcgg gtggcgttcg agcacggccc ggcggaaacg cagcaccatt
      721 tcaccggttg tttcaccgca gattccgctc acctcgacgc ggcctcgcac accgagatat
      781 tcctgtaaga cgtaaccata gggcgagtcc tgtccggacg gatgtgccgg actgggcgtt
      841 tgatatccgg ccgtgaggct atcaccgaag cagagaatga gcggagctgg attatcggta
      901 gtcacggaag aattgtactg gcacgaacag gcgggcgcaa tggcgaacgg agccctgcgc
      961 agaccggcta ttttcttgac gaatcatgca cctcacggta cgactgacac atatggaacc
     1021 tacagcccca gttggagagg gccttcctct tgcgcccttc gtgaaacccg gcaccgatcc
     1081 gcaagtcact gccatcaagc agttgttgaa gctgctcgac aaggcggcca aatcggcgcg
     1141 tacgtatggc acgaagaacc cggtcgccca gcgattcttt caacaatttt atgatgagct
     1201 gaccaatcat ctgacgcagc acactcgcct caccctgctg gtccaacgca atcaactctt
     1261 gtttcaaaac gaagtggtct acgaaccgga gcgggacgcc accggagata gctttgcgtt
     1321 caaaatgtac tcggacggga tccgtgagct gagcttccat caagggctca cgcacgaaga
     1381 cctcgccttt tttctggagg cgctctgggg catgcccgcg gacgaggcca gtccggccga
     1441 cgctgccgcc gaccaggaag aagacgacga cattgtcacg cgtttgtggg ccaagaatct
     1501 cgaaacgatt actctggtga ccgccgaaga gcttgtccgc gcctccggct tcggactcga
     1561 cgagctcgaa ctgcagacgc agggatacat gagtctgcct gtcggctcct tgcgggaact
     1621 ccttgatcgc gagcgcgcgg caaaggcctc tgacaaagag ggcacgggcg gctccgcgga
     1681 ggcggcgggc ggaaatacca ccggcggcat cgcaaaccgc aaccgtcgtt tccaggccaa
     1741 tgtcgtcggg tatgacgtct ccgacgaaga gcacgaggca ttgacccaag aaatccaacg
     1801 ggaaaccgct cgagatgcca cgacgtacat cctcgacatc ctttccgctg tcctggcctc
     1861 tgaaccatcc cctgctctgt taaccaaact attcgacgtc tgggatcacg tattggaagc
     1921 gctgattcgg gcaggacaat ggacgttgct cgaaaccgtg ctgacgatgt tgcaggaagc
     1981 agagacggtt cggcccgatc tttcggacgg ccataaacag caggtcgcgg aattattcgg
     2041 cggactgggc cgccccgagc gattgaaagc cattggcgtc catttgaatc ggaatccgca
     2101 agccaagaca gaaggcctga cgacactcct gctcatgatg aaacccgatg cgattccggg
     2161 actctgctcg gtactggcga ctctggagac gccggcccat caggcgttgg tgatggaagc
     2221 cctgcagacc ttggcgcggg accatgccga acccatcatt cgcggcctga ccgataaacg
     2281 accgactttc gtgcgcaacc tgcttaccct tatctaccga tggaatgatg cccgttttgc
     2341 cgacagcgt
//
LOCUS       DAOQPD010000177         2189 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_43967_length_2189_cov_30.339738, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000177 DAOQPD010000000
VERSION     DAOQPD010000177.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 2189)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2189)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2189
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_43967_length_2189_cov_30.339738"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..967
                     /locus_tag="PK063_18905"
     CDS             <1..967
                     /locus_tag="PK063_18905"
                     /inference="COORDINATES: protein motif:HMM:NF015588.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyl hydrolase family 65 protein"
                     /protein_id="HMZ99173.1"
                     /translation="RGRYEIHGVMGPDEFHEGYPDSPAPGLKNNAYTNIMAVWVLWRA
                     LEVLGLLPDIRREALMTRLGLSEEETARWDEISRRMYVPFHDDGIISQFEGYEKLAEL
                     DWENYRIRYGNIGRLELILEAESDSANRYKASKQADVLMLFYLFSSEELCELFERLSY
                     PFDPATIPRHVDYYDSRSSHGSTLSRVVHAWVLARSDRPRATRYFAEALQSDVNDIQQ
                     GTTAEGVHLGAMAGTVDLVQRGTMGIEVTGDVLRLNPKLPLEVKRFDMHLRYRGHSLD
                     LRLTRDALTVRGRNGGAAPIKLGIKNEVYEFAGNSTRVFKLDSPT"
     gene            1041..2186
                     /locus_tag="PK063_18910"
     CDS             1041..2186
                     /locus_tag="PK063_18910"
                     /inference="COORDINATES: protein motif:HMM:TIGR00056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MlaE family lipid ABC transporter permease
                     subunit"
                     /protein_id="HMZ99174.1"
                     /translation="MTQAAEASLNSLDARRSSDGGTLTLIMTGRWDSDTTGKWWQRGQ
                     QILEQGKPSRLVIDASGVSYCDGAGVAFLIDLQQLQIRIGGDAAIQGLPEEVRRLLDI
                     YGHISIERSPGRRREPLSIIEQVGKAAVELWRDLQALLTFIGELALTLLRAARHPRLV
                     RWHDALLVAEQSGVDALPIIALIGVLLGLILAFQSAIPMRRFGADIFVADLLGIAMLR
                     EMGPLITAIILAGRSGSAFAAELGTMKVREEIDALRTMGLEPVRFLVLPRVIAAVAMI
                     PVLTVFANLFGLMGGAIVMRSLGYPLVTYVNQVLSAVTVGDLMGGLLKSFVYGIVVAA
                     VGCLRGLETKTGASAVGQSTTSAVVSGIVLIAIVDGLFAVVFYALGL"
BASE COUNT          413 a          599 c          718 g          459 t
ORIGIN      
        1 gcgcggacgc tacgagatcc acggcgtcat gggacccgac gagtttcacg agggataccc
       61 cgactcaccg gcgcccggcc tgaagaacaa cgcctatacc aacatcatgg ccgtctgggt
      121 gctgtggcgg gcgctggagg tgctcggctt gctcccggac atacgtcgag aggcgcttat
      181 gacgcggctg ggattgtcgg aggaagagac cgcccgctgg gacgagatca gccgcaggat
      241 gtatgtgccg tttcatgacg acggaatcat cagccagttc gaaggctacg aaaagctcgc
      301 cgagttggat tgggagaact atcgcatacg gtacggcaac atcggccgcc tcgaactgat
      361 tctcgaagcg gagagcgaca gcgccaaccg ctacaaggca tcgaaacagg cggatgtcct
      421 gatgttgttt tatctgtttt cctccgaaga gctctgcgaa ctgtttgagc gtctgagcta
      481 tccgttcgac ccggcaacga ttccgagaca cgtcgactac tacgactccc gctcgtccca
      541 cggctcgacg ctgtcccgcg tggtccatgc ctgggtgctg gcgcgttccg accggccgcg
      601 ggcgacgcgc tacttcgcgg aagcgctcca gagcgatgtg aacgatattc agcagggcac
      661 caccgcggag ggcgtccatc tcggcgccat ggcgggaacg gtcgatctcg tgcagcgcgg
      721 gacgatgggg atcgaagtca cgggagacgt tctccgtctc aacccgaaat tgcctctgga
      781 agtgaaacgc ttcgacatgc accttcgcta tcgcggacat tcgctcgatt tacgactcac
      841 gcgcgatgcg ctcaccgtgc gcggacgcaa tggcggcgcg gcgccgatca aactgggaat
      901 caagaacgag gtgtacgagt tcgcgggcaa tagtacgcgc gtgttcaagc tcgactcacc
      961 gacgtgagtt gtaaggggaa cggaagacga aggagatggt gaagggagat gaggagtctc
     1021 cataacacgg ttatcgaatc atgactcaag cagcagaggc gtctctcaat tcgctggatg
     1081 cgcgccgctc gagcgatggc ggcacgctca cgctcatcat gacgggacgg tgggattcgg
     1141 acacgaccgg gaagtggtgg cagcgaggcc aacagatact ggaacaaggg aaaccaagcc
     1201 ggctcgtgat cgatgcgtca ggggtgagct attgtgacgg cgctggggtt gcgtttctga
     1261 tcgaccttca gcagttgcag atccgcatcg gcggtgatgc cgccattcaa gggttgccgg
     1321 aggaagtccg gcgccttctg gacatctatg ggcatatctc aatagagcgt tcaccgggac
     1381 gccgccgtga gccgttgtcg atcattgagc aggttggaaa agcggcggtc gaactgtggc
     1441 gggaccttca ggctcttctg actttcatcg gggagctggc gctgacattg ctccgtgctg
     1501 ctcgccatcc ccgtcttgtg cgatggcatg atgccttgct tgtggcggag cagtccggag
     1561 ttgatgcgct ccccatcatt gcgctgatcg gcgtgctgct cggactcatc ttggcgtttc
     1621 agtctgccat tccgatgcgc cggtttgggg cggacatttt cgtcgccgat ctcctgggaa
     1681 tagcgatgct tcgcgagatg gggcctttga tcactgccat tatcctggcc ggccggtccg
     1741 gttcggcgtt tgccgcagaa ctgggaacca tgaaagtcag ggaggaaatt gacgcgctgc
     1801 gtacgatggg gcttgaaccg gtccgatttc tcgttttgcc acgtgtcatc gcggcggtgg
     1861 cgatgatccc ggtcttgacg gtgttcgcca acctgttcgg tttgatggga ggagcgatcg
     1921 tgatgcggtc gctggggtat ccgctcgtca cgtatgtgaa ccaagtcctg tcggccgtga
     1981 cagtggggga cctcatgggt ggactgctga aatcattcgt ctacggtatt gtggtagccg
     2041 cggtcggctg cctgcggggt ttggagacga agacaggcgc cagtgcggtc ggccaatcga
     2101 ccaccagcgc ggtcgtcagc ggcatcgtgc tcattgcgat tgtggatggc ctctttgcag
     2161 tggtgttcta tgccttaggc ttgtaaccg
//
LOCUS       DAOQPD010000178         2164 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_44929_length_2164_cov_18.053580, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000178 DAOQPD010000000
VERSION     DAOQPD010000178.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 2164)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2164)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2164
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_44929_length_2164_cov_18.053580"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(201..1745)
                     /gene="zwf"
                     /locus_tag="PK063_18915"
     CDS             complement(201..1745)
                     /gene="zwf"
                     /locus_tag="PK063_18915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HMZ99175.1"
                     /translation="MSSPTTPLACKPVPEAVPPVEPCTLVIFGGSGDLARRRLIPAVY
                     NLLLDGLLPAKYAVIGLGRKPMTDDEFRNLVKEGIVKHSRQALAEDTWDTFKTHLFYI
                     QGENEDAQTYATLRTKAEEVEQAMQLPGNRIFYLSIPPSSFASVCEGLAQAGLATSAS
                     AASPYSRIIVEKPVGRDLASAQQINEVTGKVFDESQIFRIDHYLGKETVQNLMVVRFA
                     NSIFEPIWNHKYIDHVQITVSESEGVGTRASYYEEAGALRDMIQNHLLQLLCLVAMEP
                     PYSLDPNVVRNAKMEVLRCLRPIVGKDVEQYTVRAQYAEGVAHGQPIPGYRREKGVNS
                     NSTTETFVAVKAFVENWRWAGVPFYLRTGKALPKRASEVAVQFKDIPQILFNANPAAP
                     QPANVLTLRIQPDEGLSLRIISRVPGTRAQTHPVEMDFQYSDVFGCPSPEAYERLLLD
                     VMAGDASRFMRRDAVEASWDWVTKILDGWAQQKLRWLPEYQAGTWGPVEAERMIEHDG
                     RSWRIL"
     gene            complement(1771..>2164)
                     /locus_tag="PK063_18920"
     CDS             complement(1771..>2164)
                     /locus_tag="PK063_18920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013248741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="HMZ99176.1"
                     /translation="HYVKMVHNGIEYSMMQGYAEGFELMAKSDYRLDLGKIADVWMHG
                     SVVRSWLLELAVGALKQDPKLEQLKGYVQDSGEGRWMIQDAIDKDVPVPTLTAALFTR
                     FRSRQDESFAEKMLAALRNAFGGHSVRR"
BASE COUNT          425 a          633 c          634 g          472 t
ORIGIN      
        1 ctttcagatt cctgctgaac tcgagatcag ttcgttgcct gcgctggccc tattcgaccg
       61 gggagccttc gtgcggttta tcggggggat cgggaagaag gaagagattc gaaaacagct
      121 cctcacgtcc gtcaacattc agcatccgac gtgaagcttg tggccacggc ataggtcgac
      181 aggcatggtg cggagtccgg ctacaggatc ctccagctcc gcccgtcgtg ttcgatcatc
      241 cgttcggctt ccaccggtcc ccaggtccca gcctgatact cgggcaacca gcgcagtttc
      301 tgttgcgccc acccgtcgag aatttttgtc acccagtccc aagacgcttc taccgcgtcg
      361 cgtcgcatga agcgggaggc gtctcctgcc atcacgtcca gcaacaggcg ttcatacgct
      421 tccggcgacg ggcagccgaa cacgtcgcta tattgaaagt ccatctccac ggggtgcgtc
      481 tgcgcccgcg tgccgggaac acgcgagata atacgcagcg agagaccttc atccggttga
      541 atgcgcaacg tcaagacgtt cgccggttga ggcgccgcgg gattggcgtt gaagagaatc
      601 tgaggaatgt ctttgaattg cacggcgact tcgctggccc gcttcgggag cgctttgccg
      661 gtacgaaggt aaaagggcac gcccgcccag cgccagtttt ccacgaaggc tttcaccgca
      721 acgaaggttt ccgtcgtgga gttcgagttg actccttttt cccgccgata ccccgggatc
      781 ggctggccat gtgcgacacc ttcggcatac tgcgcccgca cggtgtattg ctcgacatct
      841 ttgccgacga taggccgaag gcaacgcagc acttccattt tggcgttgcg caccacgttg
      901 gggtcgagtg agtagggcgg ctccatggca accagacaga gcaactgcag caagtggttc
      961 tgaatcatgt cgcgcagcgc gcccgcttcc tcatagtagc tggctctcgt tcccacgcct
     1021 tccgactcac tgacggtaat ttggacgtga tcgatatact tatggttcca gatcggttcg
     1081 aaaatactgt tggcaaaccg gaccaccata agattctgaa ccgtctcttt cccgagatag
     1141 tgatcgatcc ggaaaatctg cgattcatcg aacaccttgc cggtcacttc attgatctgt
     1201 tgggcagagg ccaggtcgcg ccccaccggt ttttcgacga tgattcgcga gtagggcgag
     1261 gcggcggacg cggaggtcgc cagacctgcc tgggccaatc cctcgcagac cgacgcgaag
     1321 gagctggggg gaatgctcag ataaaagatg cgattgccgg gcaactgcat cgcctgctcc
     1381 acttcctccg ccttggtgcg gagggtggca taggtttgcg catcctcgtt ctctccctga
     1441 atgtaaaaga gatgcgtttt aaacgtatcc cacgtgtctt ccgccagagc ctgtcgcgaa
     1501 tgtttgacga ttccttcctt caccagattg cggaactcat catcggtcat gggtttgcgg
     1561 cccagcccga tcaccgcata cttggccggt aacagcccgt cgagtaatag gttgtagacg
     1621 gccgggataa ggcggcggcg ggcgaggtca ccggacccgc cgaaaatgac gagcgtgcag
     1681 ggttcgacgg gagggacggc ttccggaacg ggcttgcacg caaggggagt tgtaggggag
     1741 gacatagtct cgatagtcct ttggtgaagg tcagcgccgg acgctgtgtc cgccgaaggc
     1801 attgcgcaac gcggccagca ttttttcggc aaacgattcg tcctgccgcg accggaagcg
     1861 ggtgaacagc gcggccgtta gggtcgggac gggcacatcc ttgtcgatgg cgtcttgtat
     1921 catccaccgg ccttcgccgg aatcctgcac atagcctttc aactgttcca gcttggggtc
     1981 ctgtttcagt gcgccaacgg ctaattccag gagccaggag cgaaccacgc tgccatgcat
     2041 ccagacatcg gcaatttttc ccaggtcgag gcgatagtca cttttcgcca tgagttcgaa
     2101 tccctcggca tacccttgca tcatgctgta ttcgatgccg ttgtgcacca tcttgacgta
     2161 gtga
//
LOCUS       DAOQPD010000179         2125 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_46480_length_2125_cov_15.982126, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000179 DAOQPD010000000
VERSION     DAOQPD010000179.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 2125)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2125)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2125
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_46480_length_2125_cov_15.982126"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1243
                     /locus_tag="PK063_18925"
     CDS             <1..1243
                     /locus_tag="PK063_18925"
                     /inference="COORDINATES: protein motif:HMM:NF013044.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="aromatic ring-hydroxylating dioxygenase subunit
                     alpha"
                     /protein_id="HMZ99177.1"
                     /translation="ENAMDHVSPWATAPKLPSTHYVDNRIYTDPVIFEEEREKILAAT
                     WRLVCHESELPEPGDYRAKEIAGVPVVILRSEDRSIMAFFNVCPHRGARLVRDERGNA
                     KKGLQCLYHLWTFALDGKCTSITRSKGYDGCSLKKDDVGLRSVRTEIFCGMVFVCLKD
                     DVPPLEQFLGGMADHMKTHLGQEELEVFHYHRAIINTNWKLFVDNNSELYHEFLHVLN
                     RRTAVAHKSYHERNWLLYQNSHNIIQQGVIHYDSYGLGERSEGALPGMQPNGMVVMLL
                     FPDVMLNIRATVMRIDTMTPLAPGKTLVEWRGVGLKSDTPDVRAMRIQHHNEVWGPAG
                     RNLPEDIAAVETQWETMVQGGSRYSLFAREEGLKPQDDANLRAFYQEWGRCLGRAPND
                     PFRHGNVDTDVSHSIKEITNV"
     gene            1236..1709
                     /locus_tag="PK063_18930"
     CDS             1236..1709
                     /locus_tag="PK063_18930"
                     /inference="COORDINATES: protein motif:HMM:NF024966.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HMZ99178.1"
                     /translation="MSDVASQLFEREAIRELIARVGRLLDTKDFAAVIASFAEPGSYV
                     LRAYSPEIGKEMIWMSVKRAELLRLLKESAEHVHDLADRTHQITVDQISLEKGEALAR
                     STFSVFRTDMKGQSDLFAVGHYEDRLVKNGDTWLIDSRTVRLHTRMFTVPTPLPL"
     gene            1721..2050
                     /locus_tag="PK063_18935"
     CDS             1721..2050
                     /locus_tag="PK063_18935"
                     /inference="COORDINATES: protein motif:HMM:NF025178.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rieske 2Fe-2S domain-containing protein"
                     /protein_id="HMZ99179.1"
                     /translation="MNTQPIKLCARTDIPEGEMIEMSVPGTDNSLLLVSTKGAIRAFQ
                     NKCPHMDIPLCQGAFDGEVITCTEHLWQFDAQTGAGIEPEDAKLQQYPVSVIGDEVFV
                     ELPEAAE"
BASE COUNT          506 a          577 c          612 g          430 t
ORIGIN      
        1 ggagaacgca atggatcatg tcagtccctg ggctactgcc cctaagcttc cgtctacgca
       61 ctatgtagac aaccgaatct atacggatcc ggtgattttc gaggaagagc gagagaaaat
      121 cctggctgca acgtggcggc ttgtctgtca cgaatcggaa ctgccagaac ccggcgacta
      181 ccgggcgaag gaaatcgccg gggtaccggt tgtcatcctg cgcagcgagg accggtcgat
      241 tatggcgttc tttaacgttt gcccacaccg gggcgcgcgc ctagtgcgcg acgagcgtgg
      301 aaatgcgaag aagggcctgc agtgccttta tcatctatgg acgtttgcgc tcgacggtaa
      361 gtgcacaagc atcacccgaa gcaagggata tgacggctgc agtctgaaaa aagacgacgt
      421 tggactgcgc tctgtccgaa cggaaatctt ctgcggcatg gtgttcgttt gcctgaagga
      481 cgacgtgcca ccactcgagc aattcttggg tggtatggcg gaccatatga agacccacct
      541 tggccaggaa gagcttgagg tattccatta ccatcgcgcg atcatcaata cgaactggaa
      601 gctcttcgta gacaacaact ccgagctcta tcatgaattc ctgcatgtgc tgaaccggcg
      661 caccgccgtc gcacacaaga gctatcacga acgcaattgg ttgctttacc agaattccca
      721 caacatcatt cagcagggtg taattcacta cgacagttac gggctggggg agcggagcga
      781 gggcgcattg ccgggaatgc agccgaacgg catggtcgtc atgctgctgt ttcctgacgt
      841 gatgctcaat attcgcgcga ccgtgatgcg tatagacaca atgacgccac tcgcacccgg
      901 caagaccctc gtcgaatggc gcggcgtagg gctcaagtcc gatacaccgg acgtccgcgc
      961 aatgcggatc cagcaccaca atgaggtatg gggaccggcc ggtcgcaatc tcccagagga
     1021 tatcgccgcc gtcgaaacgc agtgggagac catggtccag ggtggatcgc gatacagcct
     1081 ctttgccagg gaagaagggc tgaaaccgca ggacgatgcc aacctccgcg ccttctatca
     1141 ggaatggggt cggtgccttg gacgcgcgcc gaatgatccg ttcaggcacg gtaatgtgga
     1201 taccgatgtt tctcattcaa taaaggagat caccaatgtc tgacgtcgca agccaactct
     1261 tcgagcgtga agcgatacgc gagctgattg cgcgcgtggg gcggctgctt gacactaagg
     1321 attttgctgc cgtcatcgct tcctttgcag aaccggggag ctatgtgttg cgcgcataca
     1381 gtcccgagat tggcaaggaa atgatttgga tgtcggttaa acgcgccgag cttctacgcc
     1441 tgttgaagga gtcggcggaa catgtgcatg acctggccga ccggacgcat cagatcactg
     1501 tggatcaaat cagcctcgaa aaaggcgagg cattggcgcg gtcgaccttt tcagtgttcc
     1561 gtactgacat gaagggacag agcgacctgt tcgccgtggg ccactatgag gatcggctcg
     1621 tgaaaaacgg agacacctgg ctcatcgaca gccggacagt acggctccat acgcgcatgt
     1681 tcacagtgcc aacccccttg ccgctttaac gagataactg atgaatacgc aaccgatcaa
     1741 gctatgtgcc aggaccgaca ttccggaggg tgagatgatc gaaatgtccg tcccgggcac
     1801 tgacaacagc ctgctcttgg tctctaccaa aggagcaatc cgtgccttcc agaacaagtg
     1861 tccacatatg gacatcccgc tttgccaagg cgcctttgat ggtgaagtaa tcacttgtac
     1921 agaacatctt tggcagttcg acgcacagac gggcgccggg attgaacccg aggacgcaaa
     1981 actgcaacag tatcctgtga gcgtcatcgg cgacgaggtg ttcgtcgaac tcccggaagc
     2041 ggccgagtaa ttgcctggtc ttgccggata gaaccagcaa gaccaggcaa taaaggcgga
     2101 tatcgcccat ttctttccgc actag
//
LOCUS       DAOQPD010000180         2106 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_47305_length_2106_cov_32.188688, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000180 DAOQPD010000000
VERSION     DAOQPD010000180.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 2106)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2106)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2106
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_47305_length_2106_cov_32.188688"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(83..574)
                     /locus_tag="PK063_18940"
     CDS             complement(83..574)
                     /locus_tag="PK063_18940"
                     /inference="COORDINATES: protein motif:HMM:NF014618.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional nuclease family protein"
                     /protein_id="HMZ99180.1"
                     /translation="MMDAAAPQHDASELVALSVKQVLDDGNTDTRIVVLKSEDASVTL
                     PIWVGSAEGNAIRLAMEHVVTPRPMSHDLIRSFADHLGVRIERIVITDVKSSTYYASI
                     AFASKGLHRTLDARPSDAIALALRAGCPIYATQDVLNRRTAVHLDAWINKLDANNTET
                     QQA"
     gene            complement(574..1029)
                     /locus_tag="PK063_18945"
     CDS             complement(574..1029)
                     /locus_tag="PK063_18945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional nuclease family protein"
                     /protein_id="HMZ99181.1"
                     /translation="MITQMRVKGLIFDPYNNAYIVVLRDEENSDMLPIWVGKSEASAI
                     GLALESVTAPRPMTHDLMKAFLETFDAKIISVVITDLNDNTYFATIHLMYEDSEYTVD
                     SRPSDAIALALRTSAPIFASEKVIKKQSSEELEQWLENLKPEDFGKLDS"
     gene            complement(1248..1529)
                     /locus_tag="PK063_18950"
     CDS             complement(1248..1529)
                     /locus_tag="PK063_18950"
                     /inference="COORDINATES: protein motif:HMM:NF016265.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(2+)-trafficking protein"
                     /protein_id="HMZ99182.1"
                     /translation="MADVQCVTCGQAGEAITDMLFLGKLEAEIKAKVCKPCWKKWEGM
                     RVMVINEYQVNLGDESGRELVKKQMKAFLKLGEQTDTSKLDQNYRPAGT"
     gene            1706..1792
                     /locus_tag="PK063_18955"
     tRNA            1706..1792
                     /locus_tag="PK063_18955"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1740..1742,aa:Leu,seq:caa)
BASE COUNT          449 a          553 c          569 g          535 t
ORIGIN      
        1 ttagcgggtt tctcgagata cgtttttgtc atggtctcca tctactcctg cacgaaagga
       61 ttctaatgtg agggatcagg cctcacgcct gttgagtctc agtattgttg gcatccagtt
      121 tattgatcca tgcgtccaaa tgcacggccg tccgccggtt caggacatcc tgtgtcgcat
      181 aaatcgggca cccggcgcga agcgcgaggg cgatggcatc gctcggtctg gcatccaatg
      241 ttcgatgaag ccccttggac gcaaacgcga tgctcgcgta gtacgtactg cttttgacat
      301 cggtaatgac gatccgctcg attcgaacgc cgaggtgatc cgcaaaactc cggatgaggt
      361 cgtggctcat cggtctgggc gtcaccacat gctccatggc gaggcgaatg gcattgcctt
      421 ctgcagagcc cacccagatc gggagggtca cactcgcatc ctcgctttta aggacgacga
      481 tgcgggtatc ggtgttccca tcgtccaaca cttgtttgac ggacagtgcg accaactccg
      541 acgcatcgtg ctgtggtgct gcggcatcca tcattagcta tccagtttgc cgaagtcttc
      601 gggcttcagg ttttcaagcc actgttcaag ctcttcagac gactgttttt taattacctt
      661 ctcgctcgca aagatcggtg cgctggttct cagggcgagg gcgatcgcat cgctggggcg
      721 agagtcgaca gtgtattcag aatcttcgta catcaaatga atggtggcga aataggtgtt
      781 gtcgttcaga tctgtaatca ccacgctgat gattttggca tcaaacgttt ctaagaatgc
      841 tttcatcaaa tcgtgggtca tgggacgcgg cgcagtcacg ctttccagcg cgaggccgat
      901 ggcgctcgct tccgattttc ccacccagat cggcagcatg tctgaattct cttcgtctcg
      961 cagcaccact atataggcgt tgttataggg gtcgaaaatc agccccttga cccgcatttg
     1021 tgtaatcacg gcgggagtat ccttcccgat gtcagccaaa aaccttaaga agtagggcac
     1081 tctatcactt ctgaaaacag agtgtcaatg aattcggtgt cgtgacgggg tggcgagggg
     1141 aggtgtaggc gacgtagaca tccctattag ttgaagcagc gatgcgggca acggatggcc
     1201 cgaacacctg cttgatcagg caggtgacgg gcggtctccg ctgaggtcta ggtgccggcg
     1261 ggccgataat tctgatccag tttggaggtg tcggtttgtt cgcccagctt caggaacgcc
     1321 ttcatctgtt ttttgaccag ttcgcggccg ctttcatcgc cgagattgac ttgatactcg
     1381 ttgatgacca tcacgcgcat gccttcccac ttcttccagc agggtttgca gaccttcgcc
     1441 ttgatttccg cttcaagttt gcccaggaac agcatatccg taattgcttc gcctgcctgg
     1501 ccgcaggtga cacactgcac atctgccatg gttgcctcca tacaattcgc gaattctgat
     1561 tggatgctaa acgcggtatt ctagcatccg gctcgttgag aaaaaagagt gcgccgcggc
     1621 gattgacgag cctgtgggtt cgtgttaaaa atgcgtcccc tcaaatctga ggatcatgag
     1681 ctgaatgtcg caggacgaga cagatgcccg gatggcggaa ctggcagacg cgccggactc
     1741 aaaatccggt tctcgcaaga gagtgggagt tcgaccctcc ctctgggcac cattcgtatc
     1801 gcggccacca gtcagctcga gactccttcc gacattttca gtcatgccac cattgttaga
     1861 actgaatcgc agtgaaacgg gaatgaattg ggctgtgtca ctgacgacaa caccatatag
     1921 tggatgtcac ggccgaaaac ctcttgacat gatgtggggg ttagcctata gttcgcccga
     1981 atttgctgtg gaatacttat gactcagtta gtttattgtc gtccatcatc aatctcttat
     2041 caattccaac tcactaagga ggcagcacat gcgtaacgtg ttggcacttg gagctgcggt
     2101 gctttt
//
LOCUS       DAOQPD010000181         2003 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_51936_length_2003_cov_22.986653, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000181 DAOQPD010000000
VERSION     DAOQPD010000181.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 2003)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2003)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2003
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_51936_length_2003_cov_22.986653"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            3..533
                     /locus_tag="PK063_18960"
     CDS             3..533
                     /locus_tag="PK063_18960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HMZ99183.1"
                     /translation="MLNSTYEPLRVLHWQKAITLLWQGKVEVLEVYDRQIHGISISIK
                     LPSVMRLLKLVKLKDSHRAVKFSRINIFTRDGYCCQYCKHKFRTEELTFDHVVPIAKG
                     GRKTWENIVTACWRCNNRKSGRTPEEANMRLIKKPVKPRWSPTVTITIGIRNTPESWR
                     DYLYWNLELDADSPDT"
     gene            complement(546..998)
                     /locus_tag="PK063_18965"
     CDS             complement(546..998)
                     /locus_tag="PK063_18965"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99184.1"
                     /translation="MAGYTGRSLAMAGGIIGLAAVAAYFGVAHIGEPDQGGGSIAGQV
                     QIAPNLADQVKPTDVLFVIVRRPTGPPRPIAAKRFDGPKFPVQFEITNDDVMVKGNEL
                     KGMVDVIARLDRDGQAGQPQPGDMEGRYPKNPTLPGGRDLMITIDKVY"
     gene            1171..1830
                     /locus_tag="PK063_18970"
     CDS             1171..1830
                     /locus_tag="PK063_18970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HMZ99185.1"
                     /translation="MAANSGFQISLDVRGWPVLVIGGNEEAAEKVQRLLDAGAKVTVV
                     SPTLHEMLRKLAASAKIIHRGRHFRANDLESVILVLNTLRDDRELAHSLIRLAREQKF
                     LLWSVDQPDVSNVVMPAVVSSGHVRVAISSSGQAPALSGFMKEDLERILDSEFAAFVD
                     WLAQLREQAKANEPDAEKRRALLREALDGFRLLGKVQYPKVWQEQRASQQAPAAPAST
                     T"
     gene            1868..>2003
                     /locus_tag="PK063_18975"
     CDS             1868..>2003
                     /locus_tag="PK063_18975"
                     /inference="COORDINATES: protein motif:HMM:NF014022.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HMZ99186.1"
                     /translation="MSPLGKGESVSKYVARSLDIIDKSGVDYRLNPMGTVLEGEWDEV
                     M"
BASE COUNT          424 a          581 c          581 g          417 t
ORIGIN      
        1 tgttgctcaa ctccacctat gaaccgctgc gtgtcctgca ttggcaaaag gccatcacct
       61 tgctctggca ggggaaggtc gaagtcctcg aagtctacga ccgtcaaatc cacggcatct
      121 cgatctcgat caaactcccc tcggtcatgc ggctcctgaa gctggtcaag ctcaaggaca
      181 gtcatcgcgc cgtgaagttt tcccgtatca acattttcac ccgcgacggc tactgctgcc
      241 aatactgcaa acacaagttc cgcacggaag aactcacgtt cgatcacgtc gtgcccattg
      301 cgaaaggcgg ccggaagacc tgggaaaaca tcgtgacggc ctgttggcga tgcaacaacc
      361 ggaagagcgg gaggacgccg gaagaagcca acatgcgtct gatcaagaaa cccgtcaagc
      421 ctcgctggag ccccacggtc accatcacca tcgggattcg caacaccccg gaaagctggc
      481 gtgattatct ctattggaat ctcgagctgg acgccgattc tccggacacc tagcgtcctt
      541 agccgttaat agaccttatc gatcgtaatc atgagatcgc ggcccccggg cagggtcgga
      601 ttcttcgggt accgtccttc catatcgccc ggttgcggtt ggccggcttg gccatcgcga
      661 tccaggcggg cgatcacatc gaccatccct ttcagctcat ttccctttac catcacatcg
      721 tcgttggtaa tttcgaactg gacgggaaac ttcggtccgt cgaatcgttt ggccgcgata
      781 ggtcgcggag gaccggttgg tcggcgcacg atgacaaaca gcacgtccgt cggtttgacc
      841 tgatcggcca gattgggagc aatttgtacc tgtcctgcga tcgatcctcc gccttgatcc
      901 ggctccccga tgtgggccac accgaaatag gctgccacgg ccgccaggcc gatgattccg
      961 ccggccatcg ctagggaccg tcctgtatat ccagccacaa tacactcctt tgttggcgca
     1021 agagctctga aagcgaccgt cttgaactgc gggcgcatta tacccagctc atagcgtaaa
     1081 ggggaatggc gcggacggtt taccctgcga aatgccctgt tgtatgatac gcgttcacgt
     1141 tattctcggc ttgttggagg aacatcaatc atggctgcaa attccgggtt tcaaatttcc
     1201 ctcgatgtgc gcgggtggcc ggtcctcgtc attggcggca atgaggaagc ggctgagaag
     1261 gtgcagcggc tgttggatgc cggcgccaag gtgacggtcg tcagccccac gctccacgaa
     1321 atgcttcgca agctcgcggc ctctgcgaaa atcattcatc gcggacgaca ctttcgcgcc
     1381 aacgatctgg agagcgtcat tctggtcttg aacaccttac gcgatgatcg cgaactcgcg
     1441 cattcgttga tcaggctggc tcgcgaacag aaattcctgc tatggtccgt cgaccagccc
     1501 gatgtttcga acgtcgtcat gcctgctgtc gtcagctccg gccacgtgcg tgtggcgatc
     1561 agctccagcg gccaggcgcc ggccttatcg ggattcatga aagaagatct ggaacggata
     1621 ctggatagcg aatttgccgc ttttgtcgat tggctcgccc agctacgcga gcaggcaaag
     1681 gccaacgagc cggatgccga gaagcgccgc gcactcctgc gtgaagcgct ggatggattc
     1741 cgtctcctgg gcaaggtgca atacccgaag gtctggcagg agcagcgcgc cagtcagcag
     1801 gcgcccgcgg ccccggcatc gacgacatag gaaggacaac tggaccatgg tgttattgga
     1861 attcagcatg tcgccgctgg gcaagggcga aagtgtcagt aagtatgtcg cgcgctcgct
     1921 ggacattatc gacaagagcg gagtggacta tcgattgaat ccgatgggca cggtgctgga
     1981 aggggagtgg gacgaggtga tgg
//
LOCUS       DAOQPD010000182         2001 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_52025_length_2001_cov_23.967112, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000182 DAOQPD010000000
VERSION     DAOQPD010000182.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 2001)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2001)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2001
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_52025_length_2001_cov_23.967112"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            713..>2001
                     /locus_tag="PK063_18980"
     CDS             713..>2001
                     /locus_tag="PK063_18980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003979 - UDP-glucose 6-dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HMZ99187.1"
                     /translation="MAKKMQRQIAVVGLGYVGLPIAVAFGKSAPVIGFDINKTKIDEL
                     RKGVDRTGEVSPQDLKSSRVRYTCEPSDLKTADFIIVAVPTPINDALQPDLTALKKAS
                     ELIGANLSPGAIVVYESTVYPGATEEDCLPILEKASGMKSGIDFKIGYSPERINPGDK
                     EHTLERIIKVVSAQDEESLEIVAQTYGLVVKAGIHRASSIKVAEAAKVIENTQRDLNI
                     ALMNELALIFHRLGIDTRSVLEAAGTKWNFLKFNPGLVGGHCIGVDPYYLTAKAESVG
                     YHPEVILAGRRINNSMGKYVAEQTMKLLSQVERPVSDLRVGVLGLTFKENVPDLRNSK
                     VPDIINELKEYGIQVVVHDPLAEHEEAVGEYGLRLSSWDQLKQLDCIILAVAHREYLN
                     MSVPELLKPLRKQRNNVVVDVKSVLSPETLPGSVKYWR"
BASE COUNT          487 a          463 c          595 g          456 t
ORIGIN      
        1 acgccggcag cctgggtctg tggggcggtg aacccgaaag ttagggttaa cacggccaca
       61 atagtagcca acctcttgga ggcgtgaagt gttgcgttgc cgtccatgat tgtcctcttg
      121 ttcgtagtga gaatgtgggt ggttgctaat ctggccatgc gaccggtcta tcgatactag
      181 agcggaacca gcagggtaac tgagactacg gagctaattc ccgtcctgaa gaattgcccg
      241 cccttcgtga gtatgagcaa gatcaatgcc tgcagcgtcc aaaacggtct taccatacaa
      301 tagcctccct aagcttgcaa atggtttcat gattctttgg gggcgcgagt gagtcatctc
      361 aatgaagaaa gcaattcacc cacaaccctt agtgtgtgta tgtgaggaca gcctcggcca
      421 aaatcgttcc tttcgggaac acgtggcgtc tggcaatcag aagcagccga tgtggcagga
      481 tgcaactcca gtgaactgga atgcctcacc tgagtacagg tgaggatgat tccgtgatgt
      541 gagcggttcc tcttcttcga gtcgagaatg tagcgccacg catagtgttt gggaaaccga
      601 aagaaatctg gatatgatag tcctgggaaa tcgttgacgg attggcgata ttctgccatt
      661 cttttttcaa cattgaccgg gtggtgcggg tgtgactgac aaggggagtg acatggccaa
      721 gaagatgcag cggcagattg cggtagtggg attgggatac gtcggactgc cgatagcggt
      781 ggcgtttggt aaatctgcgc cggtaatcgg gttcgatatc aataagacca agatcgatga
      841 gttacgcaaa ggtgtcgatc ggacaggaga ggtctcgcca caggacttga agtccagtcg
      901 agttcggtac acgtgtgagc cgagcgatct gaagacggcc gattttatta tcgtcgcggt
      961 gccgactcca atcaatgatg cgcttcagcc ggatctcacc gccttaaaga aagcttctga
     1021 actcattggt gcgaatctat cccccggcgc catcgtcgtc tatgagtcca cggtgtatcc
     1081 cggcgccacc gaagaagact gtctgccgat tctcgaaaaa gcctccggga tgaaaagcgg
     1141 catcgacttc aagatcgggt attcgccgga gcgcatcaat ccaggcgata aagaacatac
     1201 gctggagcgc atcatcaagg ttgtttcggc gcaggatgag gagtcactgg aaattgtcgc
     1261 acagacgtat ggtctggtgg tcaaggccgg aattcatcga gcgtccagta tcaaggtggc
     1321 ggaagcggcg aaggtgatcg aaaatacgca gcgagacttg aatatcgccc tcatgaacga
     1381 actggctttg atttttcatc gcttaggaat cgatacgaga tcagttctgg aagcggccgg
     1441 aacaaagtgg aactttttga aattcaatcc gggcctggtc gggggacatt gtataggcgt
     1501 agacccttat tatctgaccg caaaagcaga atcagtaggg tatcaccccg aagtcatcct
     1561 ggccggtcgg cgcatcaaca acagcatggg gaaatatgtg gctgaacaga ccatgaagct
     1621 gttgagccag gtcgaacgcc ccgtcagcga tttacgtgtc ggcgtgctgg ggttgacctt
     1681 caaggaaaat gttccggatc tgcggaatag caaggtgcct gatatcatca atgaattgaa
     1741 ggagtatggg attcaggtcg tcgtgcacga tccgctcgct gagcatgagg aggcggtggg
     1801 tgagtatgga ctgcgcctgt cgtcctggga ccagctcaaa cagcttgatt gcattatcct
     1861 ggcggtggcg caccgtgaat atttgaacat gagcgtgccg gagctgctga aacccttgcg
     1921 gaagcaacgc aacaatgtcg tggttgacgt caagagcgtc ttgagtccgg agaccctgcc
     1981 gggctctgtg aaatattggc g
//
LOCUS       DAOQPD010000183         1933 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_55671_length_1933_cov_21.009052, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000183 DAOQPD010000000
VERSION     DAOQPD010000183.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 1933)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1933)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1933
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_55671_length_1933_cov_21.009052"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..961)
                     /locus_tag="PK063_18985"
     CDS             complement(<1..961)
                     /locus_tag="PK063_18985"
                     /inference="COORDINATES: protein motif:HMM:NF014336.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1/P1 nuclease"
                     /protein_id="HMZ99188.1"
                     /translation="MSALLILLLTIAGWSFTAQAWAFGDLGHRTVGAIADAQLTPETR
                     AAVWTLLRSGETLATVATWPDEVKRAKKNLGPLAHDAEAQRFNEDFPDNREWHYVDLP
                     LDTAVYTEGAVGSRLNDIVQTIQRCIRVIESQTVSDHEMTRAQALRWLVHLLGDLHQP
                     LHLGSGYYQFDAQRQAHLITDPHEAAGKDEDRGGTLLLTAAEEQLHAFWDDRLVNEVA
                     KGRSYLELAQDLLAQGHQGAWDGDGSYHHWVDQWAVEGIRLGKSAYERLVFGTAQFDG
                     DHTGLRKITITLPRGYEQDEAKIVEQQLAKAGYRLAAILNALRF"
     gene            complement(1231..>1933)
                     /locus_tag="PK063_18990"
     CDS             complement(1231..>1933)
                     /locus_tag="PK063_18990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013250024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99189.1"
                     /translation="ATYRDPKTGADISTKNSWIADVIVDRTIQGYETRQNYRDVALFF
                     QDEDNIIGTSFMPYVQNTAGLTAVNYRAEPYKFREASGCSLGKVFQPCSVDKPESIAT
                     PIIEAHAGDPVRIHVFGASNEQNGMFSVEKHEWPIEPFMRGADQISVVEFSASESLDA
                     FIQAAGGSFRQPGDYVWSNQRLPYAQSGQWGLLKVLPTDDQRILPLSQQAPSVKRAGS
                     ESGEAHASKTSHLIQ"
BASE COUNT          406 a          569 c          549 g          409 t
ORIGIN      
        1 ggaaccgcag ggcattcaag atcgcggcaa gacgatagcc agccttggct aactgctgct
       61 ccacaatttt cgcctcatct tgttcgtagc cccggggcag ggtgatcgta atcttccgca
      121 gaccagtatg gtctccgtcg aattgcgccg tgccgaacac gaggcgctca taagccgact
      181 ttcctagcct gatgccctca accgcccact gatcaaccca gtgatgatac gagccgtcgc
      241 cgtcccaggc tccttgatgg ccttgtgcca gaagatcctg agcgagttcc agatacgacc
      301 ggcctttggc tacctcgttc accagacggt catcccagaa ggcgtgtagc tgctcttcgg
      361 ctgcagttaa taacagggtg ccgccacggt cttcgtcctt ccccgccgct tcatggggat
      421 cggtgatgag gtgggcctga cgttgagcat cgaactgata ataaccactg ccgaggtgga
      481 gcggctggtg aaggtcgccg agtaaatgaa ccagccagcg caaggcctgc gccctggtca
      541 tctcgtgatc agaaaccgtc tgtgattcaa tgacacggat gcagcgctga atcgtctgca
      601 caatgtcgtt gaggcggctt ccgaccgctc cttccgtata gacggcggta tccagcggaa
      661 gatcgacata atgccattcc cgattgtcgg ggaagtcttc gttgaaacgc tgagcctcgg
      721 cgtcatgggc caatggcccg agatttttct tggcgcgttt cacctcgtcc ggccaggttg
      781 cgaccgtcgc caaggtttcg cccgaacgaa ggagggtcca aactgccgcc ctcgtttcag
      841 gtgtgagctg ggcatcggca atggctccga ccgttcgatg gcccagatct ccaaaggccc
      901 aggcctgagc ggtaaaggac cagcccgcga tcgtcaaaag aaggatgaga agtgctgaca
      961 taccaagccc tcgcttcgag ccgggatgaa agccgtgaca ggaacgatct gttgtgcgac
     1021 agggaggatt gtagaagtta ccgagtacaa gcgcaaacat cagcccgccc caactgtcgt
     1081 tttgagctga atgctgacgc aacacagatc ggacaccaat ttatgacaaa taaaaagggg
     1141 gaagcctttc ggcttccccc ttggtgatta ggaccggcac tgcatcctta cggcggcccc
     1201 ttcgatagaa gaggccgccg ccccctcacc ttattggatg agatgtgaag tcttcgaggc
     1261 gtgcgcctcg ccggactcag atcccgcccg cttgacagaa ggtgcctgct gactcaacgg
     1321 gaggattcgt tggtcatcgg tgggcaacac cttcaagaga ccccattgac ccgattgggc
     1381 atagggcaag cgctgattgc tccacacata atcgcccggc tgacggaagc ttccgcctgc
     1441 cgcttggatg aaggcatcca gcgattctga cgccgagaac tccacgacgc tgatctggtc
     1501 ggcgccgcgc atgaacggct cgatcggcca ttcatgtttt tccacactga acatgccgtt
     1561 ctgttcattg ctggcaccga agacatggat gcgcacggga tcgcccgcat gcgcttcgat
     1621 gatcggagtg gcaatgcttt ccggtttgtc caccgagcag ggctggaaca ccttgccgag
     1681 cgagcagccg ctggcttcac ggaacttata cggttccgca cggtagttca cggccgtcaa
     1741 acccgccgtg ttttgcacgt agggcatgaa gctcgttcca atgatgttgt cctcatcctg
     1801 gaagaacagg gccacatcgc gatagttctg gcgagtttcg tagccctgga tcgtccgatc
     1861 cacaatgaca tcggcaatcc agctgttctt ggtggagata tccgcaccgg tcttcggatc
     1921 gcgataggtc gcc
//
LOCUS       DAOQPD010000184         1910 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_56968_length_1910_cov_19.443127, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000184 DAOQPD010000000
VERSION     DAOQPD010000184.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 1910)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1910)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1910
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_56968_length_1910_cov_19.443127"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..597
                     /locus_tag="PK063_18995"
     CDS             <1..597
                     /locus_tag="PK063_18995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HMZ99190.1"
                     /translation="QQLDGTFSVGLGPHKRYRQHRETIDRLSRAIANATTVQIRYDSA
                     SRGRTTRREVDPYRLWYATGGLYLIAFCHLRREPRMFAVERIKSVTPTDHPYQMPLHF
                     DLDAFVQDALTVMRGPRIEVELEFNKATAAWVKDRVWHATQATKRAKGGGLRMTLAVA
                     DTRELVGWILSFGSGVKVLKPESLHQAVVDEALRISKT"
     gene            709..>1910
                     /locus_tag="PK063_19000"
     CDS             709..>1910
                     /locus_tag="PK063_19000"
                     /inference="COORDINATES: protein motif:HMM:NF012593.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HMZ99191.1"
                     /translation="MTKTNPTSNCLPMPLYTQVLIAVIFGGLLGVIFGQEPYLGGITN
                     AQLGKLGMVVVQLLKTLAIPLIFFAILDALIRTSLPLSQGTRLLVICLVNVTVAMTIG
                     LVIMNTWQPGLSWQGHVDQLLQLVPGSKGPAKVATSQTPIEDLAAYIPRTILSPFSTN
                     NIIGVVLLALVLGTGLRRMHIKAARTGADDHAVVRGVEWVYEWLVRILGWIIHLVPLA
                     VFGVVAQVVGKSGVGVFSVLWIFLVAMLAGLTIHSFIYYPLVAWFVGKKSPKVYVGEG
                     ADAIMTAMSCNSSLATVPVTLQCLHRMNVSAQSARLAACVGTNLNNDGITLYEAMAAL
                     FLAQALGYDLSLTSQFLIVAASIIAGAGVAGIPEAGLIVLPLVLSAAGLPDTVIAAAI
                     PLIMTVDW"
BASE COUNT          326 a          599 c          583 g          402 t
ORIGIN      
        1 caacagctcg acggcacgtt cagtgtcggg ctcgggccgc acaagcggta ccggcagcat
       61 cgtgaaacca tcgaccggct cagccgcgcc atcgccaatg ccacgaccgt gcagatccgg
      121 tacgactccg cctcacgggg ccgcacgacc aggcgcgagg tcgatcccta tcggctctgg
      181 tatgccacgg gcggcctcta tctcattgcc ttctgccatc tgcggcgcga gccgcgcatg
      241 ttcgccgtgg agcggatcaa gtccgtcacg ccgaccgacc atccctatca gatgccgcta
      301 catttcgatc tcgatgcctt cgtgcaggac gcgctcacgg tgatgcgcgg cccgcgcatc
      361 gaagtggaat tggaattcaa caaggccact gcggcctggg tcaaggatcg cgtctggcac
      421 gccacccagg cgacgaagcg cgcgaaaggc ggcggcctgc gtatgaccct tgccgtcgcg
      481 gacacgagag aattggtcgg ctggatactc agtttcggca gcggcgtgaa agtcctcaag
      541 ccggagagtc tgcatcaggc ggtggtcgat gaagccctcc gcatcagcaa gacctagtct
      601 ctttcctcat ttcactccaa acgtctgcct cgtcacgttg caccattcac gctcctccga
      661 tggtgctttc tgcgcaggaa acgggtattc tcggcaattc ggtcatttat gacgaagacc
      721 aaccccacat ccaactgcct cccgatgccc ctctatacgc aggtgctcat cgccgtgata
      781 ttcggcggtc tgctcggggt gatcttcggc caggagccgt acctgggcgg catcacgaac
      841 gcgcagttgg gcaaactcgg catggtcgtc gtgcagttac tcaagacgct ggccattccg
      901 ctgatcttct tcgccattct cgatgcgctc atccgcacca gtctgccgct cagccagggg
      961 accaggttgc tggtcatctg tctggtcaac gtgaccgtgg cgatgacgat cggcctggtg
     1021 atcatgaata cctggcagcc gggcctgtcc tggcagggcc atgtcgatca attgctgcaa
     1081 ctcgtgcctg gctcaaaagg cccggccaag gtggcgacct cacaaacgcc gattgaagat
     1141 ctcgcggcct acatcccgcg cacgatcctt tcgccctttt ccaccaacaa catcatcggg
     1201 gttgtgttac tggccctggt gctcggcacg ggattgcggc gcatgcacat caaggcggcc
     1261 agaaccggag cggacgatca tgcggtcgtg cgcggggtgg agtgggtgta cgaatggctg
     1321 gtgcgcattc tcggctggat cattcacctg gtgccgctgg cggtgtttgg cgtcgtggca
     1381 caggtggtcg gcaaatcggg cgtgggcgtg ttctcggtgc tctggatctt tctcgtcgcc
     1441 atgctcgcag gcctgacgat tcattccttc atttactacc cgctggtcgc ctggttcgtg
     1501 ggcaagaaat cgcctaaggt ctatgtgggg gagggggccg atgcgatcat gacggccatg
     1561 tcctgcaaca gcagtctggc tacggtgccg gtcacgctcc agtgcctgca tcggatgaac
     1621 gtgtctgcgc agtcggcgcg cctcgcagcc tgtgtcggca cgaacctcaa taacgacggc
     1681 atcacgctct acgaagcgat ggccgcgctc tttcttgccc aggccctggg gtacgacctg
     1741 tcgctgacga gccagttcct gatcgtggcg gcttccatca ttgccggggc cggcgtggcg
     1801 ggtattcccg aggctggatt gatcgtgttg cccctcgtgc tgtcggcggc cggtttaccg
     1861 gatacggtga tcgccgccgc cattccgctg atcatgacgg tggattggat
//
LOCUS       DAOQPD010000185         1874 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_59060_length_1874_cov_25.240792, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000185 DAOQPD010000000
VERSION     DAOQPD010000185.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 1874)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1874)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1874
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_59060_length_1874_cov_25.240792"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1834)
                     /locus_tag="PK063_19005"
     CDS             complement(<1..1834)
                     /locus_tag="PK063_19005"
                     /inference="COORDINATES: protein motif:HMM:NF014900.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase family protein"
                     /protein_id="HMZ99192.1"
                     /translation="MNAIVDPQKSTTKAVTRVLNLKKAVQAEEYAVCIERAMLWTQFS
                     KNKNNKAKSRPVFIAEATRHVLRNKTVEIYPEELVVGNFTAHRVGGIIYPEMTGIAPM
                     MEIFKIPTRRVNPLNIKFLDRIKLALTIPYWLTRNTAVLAFDNNEDRARFAKEQGEAL
                     QYQLYEAGGIAHLAPGYEKIIRLGAEGIIAEVEAFEAQTTDPEKLEFYRGVKISMEAL
                     GEFGDRYAAEATRVASDERDPVRRQELEKIAEVCTRVPRHGASSFYEAVQCMTLVHIA
                     IFQETLGETTCPGRIDQFLNPYYEQDLADGVITREEAKELLGAFCVKICETIPVWSET
                     TGAMLGGMTSWEVVTIGGQDSEGNDATNELSFILLELADELRMRQPNFHVRLHENTPK
                     AFYDEVIRVNFGPGSAPAMYNDETIIESMMNVGYSLEDARDYVAIGCVEPTAPGKTLG
                     STDAGMYNMALALEMALNEGKQFHSSKQIGAKTPPVSSMTCMQDVLDAYDVQTKHQLA
                     KLHRDLQAVERFHAKHHPTPLTSATLEGCLEQGVCSTQGGAKYNFSGIQGTGMAVVAD
                     SLGAIESAVFEDKWLTLEELVAHLKDNLSDEVVRTRLKGIDKFGN"
BASE COUNT          390 a          535 c          484 g          465 t
ORIGIN      
        1 cgttgccaaa tttatcgatg cctttcagcc tggtccgcac aacctcatcc gagaggttgt
       61 ctttcaggtg cgcaaccaac tcctcaaggg tgagccactt gtcctcgaac acagcactct
      121 caatagcccc cagggagtcg gccacgaccg ccataccggt gccctggatg ccggagaaat
      181 tgtacttcgc gccaccctgc gtagagcaaa cgccctgctc caggcagcct tcgagtgtag
      241 cgctggtaag aggggtgggg tggtgcttgg cgtgaaaacg ctctaccgcc tgcagatccc
      301 gatggagttt ggctagctga tgttttgtct gcacatcgta ggcgtccagt acatcctgca
      361 tacatgtcat tgaagatact ggcggagtct tcgctcctat ttgcttcgag ctgtggaact
      421 gtttgccttc attgagtgcc atttccaggg ccagggccat gttgtacatc ccggcgtcgg
      481 tggaacccag ggtcttgccc ggcgccgtgg gctcaacaca gccgatggcg acatagtccc
      541 tggcatcctc cagggaataa ccgacattca tcatggactc gatgatggtc tcgtcgttat
      601 acatggcggg cgccgaaccc gggccgaagt tcacccggat gacctcatcg tagaatgcct
      661 tgggtgtgtt ctcgtggaga cggacgtgga agttgggctg gcgcatgcgc aactcatcgg
      721 cgagctccaa caaaatgaaa ctcagttcat tggtcgcatc gttgccctcg gagtcctgac
      781 caccgatggt cactacctcc cagctggtca taccgcccag cattgcgccg gtagtttcag
      841 accatacggg aatcgtttca caaattttca cacagaaagc gccaaggagt tccttggcct
      901 cctcccgggt gatgacgcca tctgccaggt cctgctcata gtacggatta aggaactgat
      961 ctatacgacc cgggcaggtc gtctccccaa gagtttcctg gaatatcgcg atatgtacta
     1021 aggtcataca ttggaccgct tcgtaaaagc tggaggctcc gtgacgaggc acgcgggtac
     1081 aaacttccgc aattttttcc aactcctgac gacgcacagg atccctttca tcgctagcaa
     1141 ctcgcgtggc ctccgccgca taacggtcac caaattcacc tagtgcctcc atggagatct
     1201 tcacgccacg gtagaattcg agtttttccg gatcagtggt ttgtgcctcg aaggcctcca
     1261 cctcggcgat gatgccctca gcacccaatc gaataatctt ctcgtagcca ggtgccaggt
     1321 gcgcgattcc tccagcctca tacaattggt actgcagtgc ctcgccctgc tctttcgcaa
     1381 aacgcgcacg atcttcgttg ttatcgaatg caagaactgc tgtgtttctt gtgagccaat
     1441 aagggatagt taatgccagt ttaatccgat caagaaattt gatattgaga gggttaactc
     1501 tgcgggtggg gatcttgaag atttccatca tcggcgcaat gccggtcatc tcgggataaa
     1561 tgatgccgcc gacgcgatgg gcagtgaagt tgccgacgac aagctcctcc gggtagattt
     1621 ccactgtctt gtttctcaaa acatggcggg tagcctcggc gataaacacg gggcgggact
     1681 tcgccttatt gtttttgttc ttgctgaact gtgtccagag catcgcgcgt tcaatacaga
     1741 ctgcgtactc ctctgcttgc actgccttct tcaggttcag cacccttgta acggccttgg
     1801 tagtcgattt ctggggatcc actatcgcat tcatctcgct ctcctcacat ctatgtcggt
     1861 tatccagcct tagc
//
LOCUS       DAOQPD010000186         1856 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_60114_length_1856_cov_17.149917, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000186 DAOQPD010000000
VERSION     DAOQPD010000186.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 1856)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1856)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1856
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_60114_length_1856_cov_17.149917"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..720)
                     /locus_tag="PK063_19010"
     CDS             complement(<1..720)
                     /locus_tag="PK063_19010"
                     /inference="COORDINATES: protein motif:HMM:NF024880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HMZ99193.1"
                     /translation="MILSDYTPVTEKAGDWVTPEALSMVYTRYRFARDFCRGRRVLEV
                     ACGPGVGLGYFGRYADQIIGGDLTSRLLRQARGRLPGTTPLVQLQAEALPLRSASRDL
                     IVCYEALYFFQDAGKFLAECRRVLAPQGQLLLCSVNPEWPEFNPNAQGRRYYCARELS
                     ALLREAGFQPDLFGAFPVGSTSISARCLSWIKRAAVQLRLIPSSMAGKRILKRLFLGE
                     LVPFPAEVDDEMAGYVPPVSVS"
     gene            complement(717..>1856)
                     /locus_tag="PK063_19015"
     CDS             complement(717..>1856)
                     /locus_tag="PK063_19015"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF013227.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HMZ99194.1"
                     /translation="ACVEYQIVVMAYHVPFIDPRSHYAKLKPEIDRAIIDCLANGDLV
                     NRHQLKDFEQHLAQFVGVKYAVGVNSGYHALLFALLGAGVGAGHEVITVAHTFVATVS
                     AIVHCGAQPVLIDVGPDFNMDVDLIERAITPKTKALLPVHLNGRVCDMERILALADKH
                     GLAVIEDAAQALGATFDGKCAGSQGRAGCFSFYPFKVLGGFGDGGAITTNDASLARMA
                     TLLRYNGEDRATGEYHYHGQTALLDNVQAAVLDVKLRHLPEWIAHRRQIAAAYHRGLA
                     GISQLRIPQFDESRRQDIFQNYVIRTTVREPLRAYLKEQGVETLVHWQKPMWEHKGLG
                     LLVPDVPETLAICREVVSLPMSAETTEAQVEQIVAALRAFFSTQP"
BASE COUNT          435 a          581 c          495 g          345 t
ORIGIN      
        1 agaaacggaa acgggaggaa cgtatccggc catctcatca tccacctcag caggaaaggg
       61 aacaagttct cccagaaaca gccgtttcaa aatacgcttc cccgccatac tcgatggaat
      121 cagacgtaat tgaacagcgg cacgcttgat ccacgacaga cagcgcgcag aaatcgacgt
      181 cgacccaaca gggaaggcgc caaagaggtc cggctggaac ccggcctctc gtagcaacgc
      241 cgaaagttcc cgggcgcaat agtatcggcg accctgagcg ttcggattaa attctggcca
      301 ttccggattg accgaacaga gcagcaactg cccctgagga gcaagcaccc gccggcactc
      361 cgccaaaaat tttccggcgt cttgaaaaaa atagagcgcc tcataacaaa cgatgaggtc
      421 gcgggatgcc gatcgcagcg gcaatgcttc cgcctggagc tgcaccaacg gcgtagtgcc
      481 aggcaggcgc cctcgagcct gccgaagcaa ccggctcgtc aggtctccgc ctataatctg
      541 atccgcatac cgcccgaaat aaccaagccc cactccgggg ccgcaggcga cttccagcac
      601 ccgtcggcct cgacagaagt cccttgcgaa gcgatagcgc gtatagacca tcgacaacgc
      661 ttcgggggtt acccaatcgc cggctttttc tgtcacgggg gtgtaatcgg agaggatcac
      721 ggctgcgtgg agaaaaacgc ccggagtgca gcgacaatct gttcgacttg cgcctctgtg
      781 gtttcagcac tcatcggcaa cgacacaact tcccggcaga tcgcaagcgt ttcgggaaca
      841 tccggaacca gcagtcccaa tcctttgtgt tcccacatgg gtttctgcca atggaccaat
      901 gtctcgaccc cttgttcctt cagataggcg cgcaatggct cgcgaacggt cgtgcggatc
      961 acatagttct ggaagatgtc ctggcgccgc gactcgtcga attgaggaat gcgcagttgg
     1021 ctaattcccg ccagcccgcg atgataggca gcggcaattt gccgccgatg tgcgatccac
     1081 tcgggcagat gacgcaactt cacatccagc acggcagcct gaacgttatc caacaaggcc
     1141 gtctgcccat gatagtgata ttcaccggtc gcgcggtcct ccccgttata acgaaggagt
     1201 gtcgccatgc gggcgagtga cgcatcgttc gtggtaatgg cccccccgtc tccgaatcca
     1261 ccgaggacct tgaagggata aaaactaaaa cagcccgcgc gcccctggct tccggcacac
     1321 ttgccgtcga acgtcgcccc gagcgcctgt gccgcatcct cgatcacggc caatccatgt
     1381 ttgtcggcca gcgctaagat acgctccatg tcacagaccc gtccgttcag atgcacagga
     1441 agcagcgctt ttgtctttgg cgtgatggcc cgctcaatca aatcaacgtc catattaaag
     1501 tcaggaccga catcgatcaa caccggctgc gccccgcaat gcacgatcgc cgacaccgtt
     1561 gcgacgaatg tatgcgctac cgtaatgact tcatgacccg ccccgactcc ggcgccaagc
     1621 aatgcaaaca ggagcgcatg gtacccgctg ttcaccccga cggcgtactt caccccgaca
     1681 aactgagcga ggtgctgctc gaaatctttc agttgatgcc ggttgacgag atcgccgttt
     1741 gccaggcaat cgatgatcgc ccgatcgatc tcgggcttga gtttcgcgta gtgactgcgc
     1801 gggtcgataa agggaacgtg ataggccata actacgatct ggtactcgac acaagc
//
LOCUS       DAOQPD010000187         1829 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_61757_length_1829_cov_16.780722, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000187 DAOQPD010000000
VERSION     DAOQPD010000187.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 1829)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1829)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1829
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_61757_length_1829_cov_16.780722"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            923..>1829
                     /locus_tag="PK063_19020"
     CDS             923..>1829
                     /locus_tag="PK063_19020"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012745.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HMZ99195.1"
                     /translation="MPCPSPERPLVSVVIPTYKRAHLLRKAIISALAQEQAGELFEME
                     IIVVDDCSPDETAKVVAEFPRVQYLRLDQNRGASGARNAGIKRAKGKYIALLDDDDEF
                     LTHKLMVQVPILEAHPEIGVLYGQSVVTGGETPLLLWPQWGPSGNVFEEFVTTTDDFL
                     HPPTWLVRRELFEQAGFFDESKAGMEHYDMALRIAALTPWMFLSGGPVARGRYSQQGL
                     WYSTIVNGTNEQQLPKIIEAALLRLPATADADRVRRKARAAVCASIAHQRWWAGGGLE
                     PTKAHLLKAVREAPWLLQEAAVVEWL"
BASE COUNT          408 a          439 c          549 g          433 t
ORIGIN      
        1 tgaaatgtcg gctgcttaaa ggcgacatag gcgaaccgta tcatgtgcgt gtgcaatatg
       61 cgtcctggga aggtgtgaag ccggattcca aaatcggttt tcgagagaaa cgcgactgcg
      121 cgggtgccgg aattttgtac gatgtcggat ctcatctttt cgatctagta gggtttatcc
      181 ttggcccgat cgaggcggtg gcgggtagta ccttattgat cccccgcgaa cgcattgatc
      241 acaggaccgg agtgctgggt caggtagaga ccgatgatat tgcttcggca tggtttgtat
      301 gccgggatgg gattcaaggt catctcttcg ccagtcgtgc caccccaaat tctggagata
      361 aagcgtatat cgaggtggtg ggacgagaag gcgcgctccg ggcctctctg agccgtggtt
      421 ccgtagatag gttgagggtg tcacgctcta cacatccagg gtgggaacag gtgccgctac
      481 cggcggcggc ctccgacggc aagccccatt gtctcggagc gatgatgcga agttttgtgg
      541 atgcctgttt acgaaaaaga ttgaatcatg acgtcgatgc gtccttttac gacggcctcg
      601 ctgtacagcg gacaatagaa gcagtgcaag aatctgcttg ccgaccgcaa tggattcctc
      661 tggaatccgg cgttcggtgc aatgtgcctg gcgagtgaac gcagatcggt tgagaactct
      721 gtctactgcc tgtctcttga cgactgacgc acgcattacc ctcaatcaag cacgaatatt
      781 tactataaat gttcgtgcct cccgcttact agtataatgg ctagacaggc aatgtcgcat
      841 cagggtggtg ccgagactca gagaggtgag cgtctctatg aataacgagt cactttcacg
      901 ccaagaagga ggcgtgaatg caatgccctg tccttctccg gaacgtccgc tcgtcagtgt
      961 ggtaatcccg acctacaaac gcgcgcatct tctcagaaaa gctattatat ccgccttggc
     1021 acaagagcaa gccggggagc tttttgagat ggagattatc gtagttgacg attgttcgcc
     1081 cgatgagacg gcaaaggttg tcgcagaatt ccctcgagtg caatatctca gactggatca
     1141 gaatcgcggt gcgtccggcg ctcgaaatgc agggattaag cgtgcaaaag ggaaatacat
     1201 cgctcttttg gacgatgatg acgaattcct cacccataaa ttgatggtgc aggttccgat
     1261 tttggaggcg catccggaaa tcggcgtgct gtatgggcaa agcgtggtga cagggggaga
     1321 aacgccgctg ttgctgtggc ctcaatgggg gccgtcaggc aacgtgtttg aggagtttgt
     1381 cacgacaacc gacgattttc tccatccacc gacctggttg gtgcgacgcg agttatttga
     1441 acaggcgggg ttcttcgatg agagcaaggc cggaatggaa cattatgata tggcgcttcg
     1501 tattgccgcg ctgactccat ggatgtttct ctccggcgga cccgtcgcgc gcggacgtta
     1561 ttctcagcaa gggctgtggt acagcaccat cgtgaatgga acaaatgagc agcaattgcc
     1621 taagattata gaagctgccc tattgcgcct gcctgccaca gcggatgctg atcgtgtccg
     1681 ccggaaagcg agagcggccg tttgtgccag tattgcccat cagcgctggt gggctggtgg
     1741 cggtctggag ccgaccaaag ctcatttgtt aaaggccgtg cgcgaagctc cttggttact
     1801 acaagaagca gcggtggttg aatggttga
//
LOCUS       DAOQPD010000188         1824 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_62085_length_1824_cov_12.561899, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000188 DAOQPD010000000
VERSION     DAOQPD010000188.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 1824)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1824)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1824
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_62085_length_1824_cov_12.561899"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..317)
                     /locus_tag="PK063_19025"
     CDS             complement(<1..317)
                     /locus_tag="PK063_19025"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99196.1"
                     /translation="MNSIPAYKPCRSDIIGLYLSQHTGPVINAFAGDQQGTTRHRLDR
                     ANDKPYKIEKMRSDIVQNSGARAVALLSKTDLGIRLHTFPGRILHTHMIRFAYVAFKQ
                     PTF"
     gene            843..>1824
                     /locus_tag="PK063_19030"
     CDS             843..>1824
                     /locus_tag="PK063_19030"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF025025.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HMZ99197.1"
                     /translation="MVPRFREVSVSMNNESLSRQGSMNVMPCPSPERPLVSVVIPTYK
                     RAHLLRKAIISALAQEQAGELFEMEIIVVDDCSPDETAKVVAEFPRVQYLRLDQNRGA
                     SGARNAGIKRAKGKYIALLDDDDEFLTHKLMVQVPILETHPEIGVLYGQSVVTGGETP
                     LLLWPEWGPSGNVFEEFVTTTDDFLHPPTWLVRRELFEQAGFFDESKAGMEHYDMALR
                     IAALTPWMFLSGGPVARGRYSQQGLWYSTIVNGTNEQQLPKIIEAALLRLPATADADR
                     VRRKARAAVCASIAHQRWWAGGGLEPTKAHLLKAVREAPWLLQEAAVVEWL"
BASE COUNT          408 a          437 c          542 g          437 t
ORIGIN      
        1 tgaaatgtcg gctgcttaaa ggcgacatag gcgaaccgta tcatgtgcgt gtgcagtatg
       61 cgtcctggga aggtgtgaag ccggatgcca agatcggttt tcgagagaag cgcgactgcg
      121 cgggcgccgg aattctgtac gatgtcggat ctcatctttt cgatcttgta gggtttatca
      181 ttggcccgat cgaggcggtg gcgggtagta ccttgttgat cccccgcgaa cgcattgatc
      241 acaggaccgg tgtgctggct caggtagaga ccgatgatat cgcttcggca tggtttgtat
      301 gccgggatgg aattcaaggc catctcttcg ccagtcgtgc taccccaaac tcgggagata
      361 aagcgtatat cgaagtggtg ggacgggaag gcgcactccg ggcctctctg agccgtggct
      421 ccgtagatat gctgcgggtg tcacgctcta cacatccagg gtgggagcag gtaccgctac
      481 cggcaacggc ctccgatggc aagccccact gtcttggagc gatgatgcga agttttgtgg
      541 atgcctgtct gagaaatagg ttgaaccatg acgtcgatgc gtccttttac gacggcctcg
      601 ctgtacagcg gacaatggaa gcagtgcaag aatctgcttg ccgaccgcaa tggattcctc
      661 tggaatccgg cgttcggtgc aatgtgcctg gcgagtgagc gcagatcggt tgagaactct
      721 gtctactgac tatcccttga cgagtgacgc acacattatc ctcatcaacc agaatattta
      781 ctataaatgt tcgactttcc cgcttaccag tatgatgact agacaagcaa tgtttcatca
      841 gggtggtgcc gagattcaga gaggtgagtg tctctatgaa taacgagtca ctttcacgcc
      901 aaggaagcat gaatgtaatg ccctgtcctt ctccagagcg gccgctcgtc agtgtggtaa
      961 tcccgaccta caaacgcgcg catcttctca gaaaggctat tatttccgcc ttggcacaag
     1021 aacaagccgg agaacttttt gagatggaga tcatcgtagt tgacgattgt tcccctgacg
     1081 agacggcaaa ggttgtcgca gaattccctc gagtgcaata cctcaggctg gatcagaatc
     1141 gcggtgcgtc cggcgctcgc aatgcaggga ttaagcgtgc aaaagggaag tacattgctc
     1201 ttttggacga tgatgacgaa ttcctcaccc ataaattgat ggtgcaggtt ccgattttgg
     1261 agacgcatcc tgaaatcggt gtgctgtatg ggcagagcgt ggtgacaggg ggagaaacgc
     1321 cgcttttgct gtggcctgaa tgggggccgt caggcaatgt atttgaggag tttgtcacga
     1381 caaccgacga ttttctccat ccaccgactt ggttggtgcg acgcgagtta tttgaacagg
     1441 cagggttctt cgatgagagt aaggccggaa tggaacatta cgatatggcg cttcgtatag
     1501 ccgcgctgac tccatggatg tttctctccg gcggacccgt tgcgcgggga cgctattctc
     1561 agcaagggct gtggtacagc accattgtga atggaacaaa tgaacagcaa ttgccgaaga
     1621 ttatagaagc cgccctattg cgtctgcctg ccactgcgga tgctgatcgt gtccgccgga
     1681 aagcgagagc ggctgtttgt gccagtattg cccatcagcg ctggtgggcc ggtggcggtc
     1741 tggagccgac caaagctcat ttgttaaaag ccgtgcgcga agctccttgg ttactacaag
     1801 aagcagcggt ggttgaatgg ttga
//
LOCUS       DAOQPD010000189         1776 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_65380_length_1776_cov_27.081929, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000189 DAOQPD010000000
VERSION     DAOQPD010000189.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 1776)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1776)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1776
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_65380_length_1776_cov_27.081929"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1756)
                     /gene="glgX"
                     /locus_tag="PK063_19035"
     CDS             complement(<1..1756)
                     /gene="glgX"
                     /locus_tag="PK063_19035"
                     /inference="COORDINATES: protein motif:HMM:TIGR02100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004133 - glycogen debranching enzyme
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen debranching protein GlgX"
                     /protein_id="HMZ99198.1"
                     /translation="MIQQGESFPLGSTVCPDGVNFSLFSKNSTLVELLLFDHTDDAKP
                     ATVMALNPRWNRTYHYWHIFVPGIQAGQIYGYRAFGPSEPQHGLRFDSSKLLLDPYGK
                     ALAMPDCYSRVNASVPGDNCATAMKSIVADPSKYDWEGDIPLKRPFAKTVIYELHVRG
                     FTRHPSSGLSHETRGTYRGLIDKIPYLQDLGVTAVELLPVFQFDEQDAPWGLVNYWGY
                     SPISFFVPHHGYSSRKDHLGPMDEFRDMVKALHRAGIEIILDVVFNHTAEGDRAGPTL
                     CYRGLENAAYYMLEEDRSRYADYTGTGNTLNANQPIVRRLILDSLRYWVESMHVDGFR
                     FDLASILSRDEDGRPLKNPPILWDIESDPCLAGTKLIAEAWDAAGLYQVGSFIGDSWK
                     EWNGQFRDDVRSFMKGDNGTVRRVARRLLGSPDLYGHEEREPEQSLNFVTCHDGFTLN
                     DLVSYNHKHNEANGEDNRDGTDFNLSWNCGVEGPTDDPSIERLRNRQVKNFLALTLLS
                     VGAPILLMGDEVRHTQRGNNNAYCQDNDISWFDWTRLGKHADIHRFVRFLLLLRLRSP
                     LARGESSLTLNEILCRARI"
BASE COUNT          355 a          536 c          504 g          381 t
ORIGIN      
        1 cgatccttgc ccggcaaagg atctcattca gagtcagact gctctcccct cgcgccagtg
       61 gactcctcaa gcgcaacaag aggaggaacc tcacgaagcg atgaatgtcg gcatgctttc
      121 cgagtctcgt ccagtcgaac caactgatgt cattgtcctg gcaataggcg ttgttgttcc
      181 cgcgctgtgt atgccggact tcgtcgccca taagcaagat cggcgcgccg acggacagaa
      241 gcgtcaacgc caggaagttt ttcacctgcc ggttgcgcaa gcgctcgatg gacgggtcgt
      301 cggtcggacc ttccactccg caattccagc tcaggttgaa gtcggtcccg tcccggttgt
      361 cctccccgtt cgcttcattg tgtttgtggt tgtaggacac caggtcgttc agcgtgaatc
      421 cgtcgtgaca ggtcacgaaa ttgaggctct gctcgggttc tcgctcctcg tgcccataga
      481 gatcaggact gcctaacaat cgtcgggcca cccgcctcac cgtgccgttg tctcccttca
      541 tgaagctgcg gacgtcatcc ctgaattggc cgttccactc tttccaactg tctccaataa
      601 acgagccaac ctggtacagg cccgccgcgt cccaggcctc cgcgatcagc ttcgttccgg
      661 ctaggcacgg atccgattcg atgtcccaca ggatgggggg attcttcaac ggccggccat
      721 cctcgtcgcg ggagaggatc gaggccagat cgaagcgaaa gccgtctacg tgcatcgact
      781 ccacccagta gcgcaggctg tcgaggatca accggcggac aatcggttga ttcgcgttca
      841 aggtgttccc ggtgccggta tagtcggcat agcgtgaccg gtcctcctcc agcatgtaat
      901 acgctgcgtt ctccaggccg cgatagcaga gcgtcgggcc ggcgcggtct ccttccgccg
      961 tatggttgaa cacgacatcg agaatgatct cgatgccggc ccgatgaagc gccttgacca
     1021 tgtcgcgaaa ctcgtccatc gggcccaagt gatctttgcg ggaactatac ccgtggtgcg
     1081 gcacaaagaa tgaaatgggg ctgtagcccc agtagttgac gaggccccac ggagcgtcct
     1141 gttcgtcgaa ctggaatacg ggcagcaact ccacggcggt cacaccgaga tcctgcaggt
     1201 acggaatctt gtcgatcaat cctcgatacg tgccgcgcgt ttcgtgagag agaccggaac
     1261 tgggatggcg ggtaaacccg cgcacgtgca actcatagat cacagtcttg gcaaacggcc
     1321 gtttcagcgg gatatctccc tcccagtcgt atttgctagg atcggcgacg atgctcttca
     1381 tcgcagttgc gcaattgtca cccggtacgg acgcgttgac gcggctgtag cagtccggca
     1441 tagccagcgc cttcccgtat gggtcaagca acagcttgct tgagtcaaac cgcaatccat
     1501 gttgcggctc ggaaggtccg aacgcccgat agccatagat ctggccggcc tgaataccgg
     1561 gcacgaagat atgccaatag tggtatgtcc ggttccaccg gggattgagg gccatcactg
     1621 tcgctggctt cgcatcgtcc gtgtgatcga acagcagcag ttccacaagg gtgctgttct
     1681 ttgagaacag gctgaaattg accccgtcgg ggcagaccgt cgagccgaga ggaaaacttt
     1741 caccctgttg gatcacccgt ttctgctcca tttcca
//
LOCUS       DAOQPD010000190         1728 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_68850_length_1728_cov_15.390915, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000190 DAOQPD010000000
VERSION     DAOQPD010000190.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 1728)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1728)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1728
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_68850_length_1728_cov_15.390915"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            234..758
                     /locus_tag="PK063_19040"
     CDS             234..758
                     /locus_tag="PK063_19040"
                     /inference="COORDINATES: protein motif:HMM:NF013618.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HMZ99199.1"
                     /translation="MVSLVVLPDSVGAEMPPDRFWYVNHSCVVAAANRYAVTVQILEA
                     IILVESEGDPHAVNVNRDGKGDRRGPLSLKQAKALVAELWKTGANFDVGIAQINSVHM
                     RHYKIDPVHFLDPCINIQWAAFVLRQKINEYQETWTAVGRYNGSRNIAGYSWKVYRAL
                     ERLAGIRRARGLLR"
     gene            800..1249
                     /locus_tag="PK063_19045"
     CDS             800..1249
                     /locus_tag="PK063_19045"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99200.1"
                     /translation="MSNREAEQCATGNVSRARWAFDVTPGREKHVVLQLRELGCTSVE
                     RPTKGYVIAQCDPTAVPVIKGLPGVVRALPLVDTDVFEDLSNEPLPAKVSDLVQVSSG
                     PYAQMTGIVRALEGEDVLIDVSLMGRVVRVRAKAAHVSVMPLPEPWR"
     gene            1251..>1728
                     /locus_tag="PK063_19050"
     CDS             1251..>1728
                     /locus_tag="PK063_19050"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99201.1"
                     /translation="MLGRLWGAWRGGSARIDAGETTQRVVPSQIEITLEDLAKDVWLP
                     LNLDFIQQTGELVEEAEPTVSPVEHAAAELEETIAPASLASPSAPALVVGPSSAQLTT
                     PPEEVPQAATPDPATSPRPVSSGRSSALIRDFIMPYQPVIESQRALEPLLTVVKILE"
BASE COUNT          370 a          443 c          570 g          345 t
ORIGIN      
        1 cccagtgtga cggatttacg gtcgatcagt tcagcgcttt gaacttccag gcgatggatt
       61 tcaccgaatg gtacaaaaat gtgtcagcga atattgaccc ggccgtgatc acgaaggaaa
      121 tggcgacgaa aatatgtacc tacacgggca cttgttaggg cgggagtatc gtgggcgtca
      181 gggtgacatc ctccagacca caaagtctcc gttcaacgtg gctgtgtctt gcggtggtga
      241 gtctcgttgt cttgccggac agtgtcgggg cggagatgcc cccggaccgg ttttggtatg
      301 tgaaccacag ttgcgtcgtg gcggcggcga accgctacgc ggtgaccgta caaatattgg
      361 aagcgatcat tctggtggag agcgaagggg atccgcatgc agtgaatgtg aaccgggatg
      421 ggaaggggga tcgacgagga ccactatcct taaagcaagc caaggcattg gtggcggaac
      481 tgtggaagac gggggcgaat tttgatgtcg gaatcgcgca gatcaacagc gtgcatatgc
      541 ggcactacaa aatcgatccg gtccattttc tcgatccctg catcaatatc caatgggcgg
      601 cgtttgtctt gcggcagaag atcaacgagt accaagaaac gtggacagcc gtaggccgat
      661 acaacgggag tcgcaacatc gcgggctaca gctggaaggt gtaccgggca cttgagcggc
      721 tcgcaggcat cagacgagcc cgcgggttgc tgcgatgagt acgctggctg ggccggtacg
      781 gctttcgaaa ggagagtctg tgagcaaccg agaagcagag cagtgtgcca ctgggaatgt
      841 gtcgcgcgca cggtgggcgt ttgatgtgac gccaggccgt gaaaaacacg tggtcttgca
      901 gctccgggag ctggggtgca cgagcgtgga acgtccaacg aaaggctacg tgatcgctca
      961 gtgtgatccg acggccgttc ccgtgatcaa ggggctgcct ggagtggtga gagcgctgcc
     1021 tctagtagat accgacgtct tcgaggacct cagcaatgag ccacttccgg ctaaggtttc
     1081 cgatctggtg caggtcagtt ctgggcccta tgcgcagatg acggggatcg tgcgagcctt
     1141 ggaaggcgag gatgtattga tagatgtgag cttgatgggg cgggttgtgc gtgtcagggc
     1201 taaagcggcg catgtgagcg tgatgccgtt accggaaccc tggaggtgac atgctcggga
     1261 gattgtgggg agcgtggcgc ggcggctctg caagaatcga cgctggagaa acaactcagc
     1321 gggtggtacc gagccagatt gagatcaccc tggaagacct ggccaaagac gtatggctgc
     1381 cgctgaattt ggacttcatt cagcaaacag gggagttggt cgaggaagct gagccgacgg
     1441 tcagtccagt ggagcatgcc gcggctgagc ttgaggagac catcgctcct gcatccctgg
     1501 catctcccag tgcacccgct ctcgtggttg gcccatcctc cgcccagctg acgactcctc
     1561 ctgaggaagt cccacaggca gccacacccg atcccgccac ctcaccacgc ccggtgtcct
     1621 ctggccggtc gtccgcactc attcgggatt tcatcatgcc ctatcaaccg gtgattgaga
     1681 gccagcgcgc actggagccg ctgctcacgg tggtgaaaat tctcgagg
//
LOCUS       DAOQPD010000191         1679 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_72738_length_1679_cov_20.187808, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000191 DAOQPD010000000
VERSION     DAOQPD010000191.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 1679)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1679)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1679
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_72738_length_1679_cov_20.187808"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(58..>1679)
                     /locus_tag="PK063_19055"
     CDS             complement(58..>1679)
                     /locus_tag="PK063_19055"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HMZ99202.1"
                     /translation="LWYRRRSHEACMRWLHDRSIGQKFFLSFGVILSLLALSLTALLV
                     YLSRINSYVDRHKRITVPAIVTAATMQRSAYDMNLTLHLFLEQMTKTGADEALARLAS
                     HADAIRHSLQLYRSTHAARTHPILLGMLNQHQRLDLADQEDQAIAEIDQALQELNGLW
                     SAALTQAQAPGATQSATTKADALIARLTYHLDQLVAAHRDIDVEMKIEGDLLLQQARM
                     IALGLVAVLGLVIGVIYVSVNRRIAKPLQRLSITADRVAHHDLTAQFEAWPASDEVGT
                     LAASLSSMVTSLREQTAATARKTKELEAFTYSVAHDLKGPLREIEGFSSLLEKRFLEG
                     GDAETRHHIDVIRRSSLRLTHMIDALLKYSRLEQQDLPRQRFNVLEMITTLITDRFNG
                     LQGPKPKIHVALPFADLYGEPVSIRQAIANLLDNAAKFSRRTAAPTITIGGTRTDHER
                     ILWIQDNGIGFDPAQTDKIFGLFERLHNPQDYEGTGVGLAIVKLVMDKHDGRVWAEST
                     PGAGSKFSLAFPERAEIVVERASTTAPLPPA"
BASE COUNT          313 a          464 c          556 g          346 t
ORIGIN      
        1 cggacaaatt cttcgtcatc gataatcagg gtgcggatgc gttcgctgct catgatgtca
       61 ggccggcgga aggggggcgg tggttgaggc acgttccacg acgatctcgg cccgttccgg
      121 aaatgccagc gagaacttgc tgccggcacc cggtgtggac tcggcccaga ctcgcccgtc
      181 atgtttatcc atcacgagct tgacgatcgc caggcccact cccgtgcctt catagtcttg
      241 cggattgtgc agccgttcaa agaggccgaa aattttgtcg gtctgtgcag gatcaaagcc
      301 gatcccgttg tcctgaatcc acagaatccg ctcgtggtca gtcctggtgc cgccgatggt
      361 gatggtcggc gcagcggtgc ggcgtgaaaa ctttgccgcg ttgtcgagca ggttggcgat
      421 cgcctgacga atgctcaccg gctcgccata caggtcggcg aacggcaggg cgacgtggat
      481 cttcggcttc ggcccttgca gtccattgaa ccggtcggtg atcaaggttg tgatcatttc
      541 cagcacattg aagcgttgcc gaggcaggtc ctgctgttcc aagcgcgaat acttgagcag
      601 cgcgtcgatc atatgggtca ggcgcagcga agaccggcgg atgacatcga tgtggtggcg
      661 ggtttcggca tcgccgcctt caaggaatcg tttctcgagt aaagaggaga atccttcgat
      721 ctcccgcagc ggacctttga gatcgtgcgc gacggaatag gtgaacgcct ccagctcctt
      781 ggtttttctg gcggtggcgg cggtttgttc gcgcaggctc gtgaccatcg aagacagcga
      841 ggctgccaag gtcccgactt catcactggc cggccaggct tcgaactgcg ctgtcaggtc
      901 gtgatgggcg acacggtccg cggtgatcga aaggcgttgg agcggtttcg cgatccggcg
      961 gttgaccgaa acatagatca cgccgatgac gagcccaagg accgcgacca gccccaacgc
     1021 gatcatgcgg gcctgttgca gcagaaggtc cccctcgatc ttcatctcga cgtcgatgtc
     1081 acggtgggcg gcgaccagct gatccaggtg gtacgtgagt ctcgcaatga gggcatcggc
     1141 tttggtggtc gccgactggg tagcacccgg ggcctgcgcc tgcgtgagcg ccgcgctcca
     1201 taagccgttc aactcctgca gggcctgatc gatttcggcg atggcctggt cttcctgatc
     1261 ggccaggtcc agacgctggt gttgattcag cattccgaga agaatcgggt gggtgcgtgc
     1321 cgcatgcgtg gagcgataga gctgcagaga gtgacggatc gcatcggcat gcgacgccag
     1381 gcgggcgagg gcctcatccg cgccggtctt cgtcatctgt tcgaggaaaa ggtgcagggt
     1441 gagattcatg tcgtaggcgg agcgttgcat cgtcgctgct gtcacgatgg ccggcacggt
     1501 gatccgctta tggcgatcga cgtaactgtt gatgcggctg agatagacca ggagcgccgt
     1561 gaggctcaac gccaggaggc tgaggatgac tccgaaagag aggaaaaatt tctgtccgat
     1621 cgaacggtca tggagccagc gcatgcaggc ctcgtgtgag cgcctacggt accacagtg
//
LOCUS       DAOQPD010000192         1659 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_74412_length_1659_cov_24.958229, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000192 DAOQPD010000000
VERSION     DAOQPD010000192.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 1659)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1659)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1659
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_74412_length_1659_cov_24.958229"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            579..905
                     /locus_tag="PK063_19060"
     CDS             579..905
                     /locus_tag="PK063_19060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HMZ99203.1"
                     /translation="MGSKIYVGGLPYSATEQQLSDLFAVHGAVESARIITDKFTGQSR
                     GFGFVEMASSDEAQKAISALNGTDMGGRTLTVNEARPQEPRSGGPGRSGGGGGFNDRG
                     GKRDRW"
     gene            complement(1123..>1659)
                     /locus_tag="PK063_19065"
     CDS             complement(1123..>1659)
                     /locus_tag="PK063_19065"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HMZ99204.1"
                     /translation="GSYVIGTLFDGRPAGEWKILITDRAKSASQVLAQLQAKGTDQTH
                     KLLLFEGTESANLDVEVSYLAVAGKADFGGGLLWRAKDDRNYYLLRASLVEQKIRVYR
                     VVNGVQQIVKQVDRPLPATGWHKLRIVQRGCEMKALFDDAVLFRVCDTTYTSGRIGLW
                     TKADAVTYFDDLTLKVLD"
BASE COUNT          342 a          431 c          509 g          377 t
ORIGIN      
        1 ttccggcggc tggtgaatgt agccaatctt atcatatgtc cagcagtact ggacaagccc
       61 aaaacgccgt cgatcaacaa attcgtgatg atgaaaggat gtttgtgtag atctcgcgac
      121 gacaatgaac cacgcgagga ggtgagagac ggagtcggtt gcggatcatg ccagggtggt
      181 ggaccgctgt gtatcagcat tcgacaaaca gaagcggaaa tcgactaggt atatccctag
      241 tgccggcaaa ctgcggcgtg tcagctgccg atgaacggcg caaacggagg gcaagcgata
      301 gcgggtcatc atattggaca gtcgtccgtc aactctgggc cgaaatgcct atttcatggc
      361 ttgtatggca atggggcccg tggtactatt cgcggtctcc cgctggggcc tggtgaggga
      421 tgcgttgaaa tagttcaggc ctgactcgat gttgctcttg cccgggaatc taatcgaaag
      481 ccagacccaa gtcgccccgt tacgtcgcgt cttcggcccg tcctttccct ttctttcctt
      541 cgttcaagac aatgtcacta cccaagagga ggacccacat gggttctaaa atttatgttg
      601 gcgggttgcc gtattcggca accgaacagc agttgagcga tttgttcgca gtgcacgggg
      661 cggttgaatc ggcccgtatc attacggaca aatttaccgg ccaatcgaga ggtttcggat
      721 tcgtcgaaat ggcctcttca gacgaggcgc agaaggcgat ttccgctctc aatgggacgg
      781 acatgggtgg ccggacattg acggtcaatg aagcgcgtcc gcaggagcct cgttcaggcg
      841 ggcctggccg gagcggtgga ggcgggggat tcaacgatcg tggtggcaag cgcgatcgct
      901 ggtaacgcct gactttgtaa cagctcgtgg ggcagtcatc cttgtggtgg ctgccccatt
      961 tttttgtccg gatgagccgt gagggatttc tcgtacgcgc caattgggga tggtggtttt
     1021 ctgtacgccg tgaaacgcgg aagatgacaa ggcgcgattc gcgacggaaa cgctacgcga
     1081 ctcctgctat gtatgcgggg agggtgcggg gaaggttata cgttagtcga gcaccttgag
     1141 cgtgagatcg tcaaaatagg tgaccgcgtc ggctttggtc cacagtccga tccgtccgct
     1201 ggtgtacgtc gtgtcgcaga cacgaaacag aacggcgtca tcgaagagcg ctttcatttc
     1261 gcagccgcgt tgcacgatac gaagtttgtg ccatccggta gcggggaggg ggcgatcgac
     1321 ctgcttcaca atctgctgca ccccattcac gacgcgatag acacggattt tttgctccac
     1381 cagactcgct ctcaacagat agtaatttct gtcgtccttc gcccgccaca agagcccgcc
     1441 gccgaagtcg gcttttccgg ccacggcgag ataggacacc tcgacatcga ggttggcact
     1501 ctcggtgccc tcgaacagga ggagtttgtg cgtctggtcc gtccccttgg cctgtagttg
     1561 ggcgagcact tgcgaggcgc tctttgcgcg gtcggtgatg aggattttcc attctcctgc
     1621 cggtcggcca tcgaacagag ttccgatgac gtatgaacc
//
LOCUS       DAOQPD010000193         1517 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Nitrospira sp. isolate AMR_MDS_0453
            NODE_88370_length_1517_cov_26.745554, whole genome shotgun
            sequence.
ACCESSION   DAOQPD010000193 DAOQPD010000000
VERSION     DAOQPD010000193.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32810085
            Sequence Read Archive: SRR3501853
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Nitrospira sp. (wastewater metagenome)
  ORGANISM  Nitrospira sp.
            Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
            Nitrospira.
REFERENCE   1  (bases 1 to 1517)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1517)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/03/2023 07:12:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,814
            CDSs (total)                      :: 3,776
            Genes (coding)                    :: 3,765
            CDSs (with protein)               :: 3,765
            Genes (RNA)                       :: 38
            rRNAs                             :: 1 (16S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 35
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 11
            CDSs (without protein)            :: 11
            Pseudo Genes (ambiguous residues) :: 0 of 11
            Pseudo Genes (frameshifted)       :: 1 of 11
            Pseudo Genes (incomplete)         :: 9 of 11
            Pseudo Genes (internal stop)      :: 1 of 11
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1517
                     /organism="Nitrospira sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_88370_length_1517_cov_26.745554"
                     /isolate="AMR_MDS_0453"
                     /isolation_source="Domestic waste water"
                     /db_xref="taxon:70125"
                     /environmental_sample
                     /geo_loc_name="Singapore"
                     /lat_lon="1.33 N 103.75 E"
                     /collection_date="2015-06-12"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(102..>1517)
                     /locus_tag="PK063_19070"
     CDS             complement(102..>1517)
                     /locus_tag="PK063_19070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013249110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OB-fold nucleic acid binding domain-containing
                     protein"
                     /protein_id="HMZ99205.1"
                     /translation="QEQVMAIANKVAGFSLGQADILRRAMGKKKPEEMEKLRVQFLEG
                     AKQKKIAEKKADKLYELIQKFAGYGFNKSHAAAYAVVCYHTAYLKAHYPTEFMASLMT
                     TDMGNADKIVGYFTECRGLGIPVLPPDVNQSQKDFAVVDKSIRFGLAAIKNVGEGAVE
                     AVIESRQEDGPFRSFFDLFRRVDLRKLNKRMMEGLIKAGAFDSMGGRRSQYLAVLDQA
                     MDEGVSIQKERAVGQTSIFGDDVAGLPQNLADPALPDVPEWSQGELLKHERELTGFYI
                     SAHPLARYEAAIQLFANTTSMQVADVPDGREVKLCGIITAVKSMLTKKGDRMAYITLE
                     DLHGVIEVIAFPDLYRDHADMIVPEQVVRLTGTVDRGDKGTKLRGTKIEPLAELQNKG
                     ISRVMIRLHDGPTASTRLPMLRQVFQKYPGSSTVALIMALGGTIEARTSPLPNVKITP
                     SEHFVADIEEVLGKGAITLVT"
BASE COUNT          269 a          445 c          442 g          361 t
ORIGIN      
        1 ccagcttctc gattttttct tcgagttcgc ggatcggttt ttcaaagtcg aggtagtctc
       61 tcatactgct gaaccccctt aagggtgttg cctaggtttg cctaggttac caaagtgatg
      121 gcgcctttgc ccagcacttc ctcaatatcg gcgacgaaat gctcgctggg cgtgatcttc
      181 acgttgggca ggggagacgt ccgggcttcg atggtgccgc caagcgccat gatgagcgcc
      241 acggtggacg aaccggggta tttctgaaac acctgccgca gcatgggaag cctggtggag
      301 gccgtcgggc catcatgcag gcgaatcatc acccgcgaga ttcccttgtt ctgtaattcg
      361 gccagcggtt cgatcttggt cccgcgcaac ttggtgccct tgtctccgcg atcgacggtg
      421 cctgtcaatc gcacgacctg ttccggcacg atcatgtcgg catggtctcg gtacaagtcg
      481 ggaaaggcta tcacttctat cacgccatgt aaatcctcca gcgtgatgta cgccatgcga
      541 tcgccctttt tggtcagcat ggatttcacg gcggtgatga tgccgcagag tttcacttcg
      601 cggccgtccg gcacatcggc gacctgcatg ctcgtcgtgt tggcgaagag ttgaatggcg
      661 gcttcatacc gcgccagcgg gtgggcgctg atgtagaagc ccgtcaactc acgttcatgc
      721 ttcaacagtt ccccttggct ccactcgggg acatcgggca aggccggatc ggcaagattc
      781 tggggaagac cggcgacgtc atcaccgaag atgctggtct ggccgacagc gcgttccttt
      841 tgaatactga cgccttcatc catcgcttga tcgagcacgg ccagatattg tgaacgccgt
      901 ccgcccatgg aatcgaaggc ccccgccttg atgagtcctt ccatcatgcg cttgttcagc
      961 ttgcggagat ccacgcggcg gaacagatca aagaacgatc ggaacgggcc gtcctcttgg
     1021 cgcgattcga tgaccgcttc gacggcgcct tcgccgacat tcttgatggc cgcaaggccg
     1081 aaccggatgc tcttgtcgac gacggcaaag tccttctggc tctggttcac atccggcggc
     1141 agcaccggga tcccgaggcc gcggcattcg gtgaagtagc cgacgatctt gtcggcgttc
     1201 cccatgtcgg tcgtcatcag ggaggccatg aattccgtcg ggtagtgcgc cttcagatag
     1261 gcggtgtgat agcagaccac ggcatacgcg gcagcgtgcg acttgttgaa gccgtagccg
     1321 gcgaacttct ggatcagctc gtacagtttg tcggcttttt tctccgcgat ttttttctgt
     1381 ttggcgcctt ccaggaattg aacccggagc ttttccattt cctccggctt cttcttgccc
     1441 atggcgcggc ggagaatgtc cgcttgtccc agcgagaatc cggccacctt gttggcgatg
     1501 gccatgacct gctcctg
//
